PharMolix/UniProtQA huggingface dataset:
Protein: PAI2_MOUSE
Sequence: MEELSMANTMFALNLLKQIEKSNSTQNIFISPWSISSTLAIVLLGAGGNTEQQMAKVLQFNEIGSYGITTRNPENFSGCDFAQQIQKENYPSAILQAQAGDKIHSAFSSLSSTINTPQGDYLLESANKLFGEKSARFKEEYIQLSKKYYSTEPEAVDFLECAEEAREKINSWVKTQTKGEIPNLLPEGSVDEDTKMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSHESIPVQMMFLHAKLNIGYIKDLKTQILELPHTGNISMLLLLPDEIEDASTGLELLESEINFANFNKWISKDTLDEDDVVVYIPKFKLAQSYELKSILQSMGMEDAFNKGKANFSGMSERNDLFLSEVFHQASVDVTEEGTVAAGGTGAVMTGRTGHGGPQFVADHPFLFFIMDKITHTILFVGRFSSP
What is the function of this protein?
Inhibits urokinase-type plasminogen activator.  The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.  Not required for normal murine development or survival.
What are the official names of this protein?
Plasminogen activator inhibitor 2, macrophage, PAI-2, Serpin B2.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted, extracellular space.
Protein: RL13_MOUSE
Sequence: MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRNVYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAEQDVEKKK
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L13, A52.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
Protein: RUVA_BRADU
Sequence: MIGKLKGLIDSYGEDFVILDVGGVGYQVHCSTRTLQHLPSPGEAAVLSIETYVREDQIKLFGFRTDQEREWFRLLQTVQGVGAKVALAVLGTLAPSDLANAIALRDKAAVARTPGVGPKVAERIVTELKDKAPAFANVDPAVVHLAGAVDDQRAPRPVADAISALVNLGYGQPQAAAAIASASRSAGEGAETAQLIRLGLKELAK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RLMH_BEII9
Sequence: MRLQLIGIGRTKAGAERELTARYLERAGQAGRAIGFPSVELREIEESRARRGDERKAQEGKAIRALLQPASLIVAFDEHGRSIDSEGFADCLGQARDSGKAMMHFLIGGADGLEPALTESAAFVFAFGKMTWPHQLVRIMAAEQIYRAMTILGHHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_BURPS
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARPVNFHPDAEAAS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: TYSY_XENNA
Sequence: MKQYLDLMKKVLEEGTAKDDRTGTGTRSIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLNGDTNIKYLHDNGVSIWDEWADENGDLGPVYGKQWRAWGSADGRHIDQLTQVLEQLKGDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCNLDVGDFVWTGGDTHLYNNHLEQTHLQLSREPRALPKLVIKRKPDSLFDYRFEDFEIVDYDPYPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_PSESM
Sequence: MTQRKIIHIDCDCFYAAIEMRDEPELAGKPLAVGGSAERRGVIATCNYEARAYGVRSAMSSRHALKLCPDLTIVKPRMEAYKEASREIHSIFRDYTDLIEPLSLDEAFLDVSDTHHFSGSATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWKKPNGLFVITPDQVEDFVASLPVTKLHGVGKVTADKLGRLGIVDCADLRSRSKLALVREFGSFGERLWSLAHGIDDRPVQNDSRRQSVSVENTYDTDLPDLAACLEKLPALLETLGTRMERMEGQYRPGKPFVKVKFHDFTQTTLEQSGAGRDLGSYEQLLTQAFARGGKPVRLLGIGVRLHDLRDAHEQLELFST
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF13_ACISJ
Sequence: MAKEELIEMQGKVDEVLPDARYRVTLDNGHQLIAYTGGKMRKFRIRILAGDLVTLEMSPYDLNKGRVTFRHIENRTRTTPPARRRH
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 3.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVG3_SCHPO
Sequence: MFSNSKKKIFLYVLIAGVATFSFAFLVLNRLQAEEHSLAYVENLFLDPFIKQNESLAHANDRPFKLYLGIFSQAKNVDRRNFLRTDYNEYIKEFAVNDTVDVRFILGLPENEQELATIREEQRTYGDLAVLPIPENVDAGKSIVYFQTFLEGYQPFPLFSELADNLIMPSTQFHGSFIYNQSIKTYELPGMKEFQDLGEPKHDYDFIVKADDDSFLNLPRLFEMLKEHVGKSRFYFGRDCTRRELPTAVRDFPYMCGFFYIVSPDMAYEVAKRRNIIIPFEDAQTGYSIYLSGNVKNAEFSKCTLYDLILPNEGFNYRQSYLRIDAIAVHKLKSIPLLSTVSNWFKKMYEHRANCSALIETERLSCLQATIPLPSLDV
What is the function of this protein?
Involved in cell wall biogenesis.  Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation.  Has a role in meiosis.
What are the official names of this protein?
Beta-1,3-galactosyltransferase pvg3, Meiotically up-regulated gene 49 protein, Pyruvylated Gal-beta-1,3-epitope synthesis protein 3, PvGal synthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: SYH_ANAMM
Sequence: MNVGKLQPVRGTRDLLPEECYKFWHIRDVAHDIGERYGFVPVETPIFEFQDVFLKTLGDSSDIIGKEMYSFPDRGGDVLVLRPELTAAVARMLICERLTLPARLFTFGPVFRYERPQKCRQRQFHQINYEHFGAGCTADAELMALAYDILGALNLRSEVQLEINSLGNQDSILGYRNSLLKYFEKHEHALSEDSRRRLQTNPLRILDSKDRGDIAILCGAPVIADFYDDESNMTFNGVMQQLDNLGIPYTVNPRLVRGLDYYCGTVFEFKTTSLGSQDAVIAGGRYDKLVASMGGGDVPAVGFAGGVERLASLAAYSHSTRFSVAFLPLGEEAARCAMRSAYELRGRGIRVLCDGVVEKLKIGLKHADRSGVDLALILGDEEIAKGEVLCRHMDTGLQQTVSISNLGDYVSGMESNAQGNNRAALSSAGE
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTI11_ARATH
Sequence: MRKWICCTCQIEDSNEEQQLKSSQQQSDANHKNSKPAPVAKHEVKKEALPIEVPPLSLDEVKEKTENFGSKALIGEGSYGRVYYATLNDGVAVALKKLDVAPEAETDTEFLSQVSMVSRLKHENLIQLLGFCVDGNLRVLAYEFATMGSLHDILHGRKGVQGAQPGPTLDWITRVKIAVEAARGLEYLHEKSQPPVIHRDIRSSNVLLFEDYKAKIADFNLSNQAPDNAARLHSTRVLGTFGYHAPEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCIDPKLKADYPPKAVAKLAAVAALCVQYEAEFRPNMSIVVKALQPLLKPPAAAPAPES
What are the official names of this protein?
PTI1-like tyrosine-protein kinase 1, PTI1-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GCST_STACT
Sequence: MSNDLKKTPLYDRFVESNAKIVEFGGWAMPVQFSSIKEEHNAVREVMGIFDVSHMGEVLIEGKDASDFIQYILSNDTDQLTDNKAQYTALCNDKGGIIDDLITYKLDNQKYLLVVNAANTEKDYNWINSHSENFDVKVENVSDQYGQLAVQGPEARDYVGSLVDVDVSEMKPFDFKKDVTIFGKNIILSQSGYTGEDGFEIYCNSDDVVDIWDGLLENENLVPAGLGARDTLRLEAGLPLHGQDLSEDITPYEGGIAFAAKPLIEADFIGKEVLKEQKENGSAERTIGLEMLDKGIPRTGYDVLDLDGNKIGVVTSGTQSPATGKGIALAIINRDEFEMGREVLVQIRKRQVKAKIVKKNQISK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: SYY_BORHD
Sequence: MNLALGILEKRGFLKQCTNLEALSVLMDREKMVFYVGVDATSTSLHIGHLIPFMAMAHLQRQGHIPIALVGGGTTKIGDPSGKDVMRKILPKEDIEANVKAIKEQLLRIIDFSHGYIIDNSEWLDNINYIEFLRDIGVYFSVNRMLGFETYKRRLKDGLSFIEFNYQLLQSYDFYMLNKLKNCKLQIGGDDQWGNIVSGVDLVKRKLGTEVFGLTLPLITRSDGKKMGKSEKGAVYLDSKLYSVYDFYQYFRNVPDLDVKKFLYLFTFLEDDEIEHISSFQGYLLNKAKETLAFEITKIVHGESAALKASSAASAAFKGGEGDKSDIPFFKLALTSLEGTILLVDLMVSSKIVSSKSEARRLISSGGVYVDKVRIGDQNYCLNKDSFANGAIELRIGKKKILRIIL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMP17_NAUMA
Sequence: LSLQEFLGLWR
What are the official names of this protein?
Uncharacterized protein SMPP17.
Protein: SYH_COLP3
Sequence: MAKQKALQAIRGMNDCLPSETNIWQMVETVLRRVASNYGFAEIRMPIVESTALFKRGIGEVTDIVEKEMYTFDDLNGDSLTLRPEGTASCVRAGNQHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQFGLEAFGIATPDIDAEIILLTSRLWRELGINEFVTLELNSLGSNEERANYREALIAYLLEHEELLDEDSKRRMHTNPLRVLDSKNPQVQEALTNAPKLSDHFGEETQTHFDTLCARLDAAGINYVLNERLVRGLDYYNRTVFEWVTTTLGAQGTICAGGRYDGLVEQLGGKATPAFGFALGIERLVLMLTELEKVTNIRPQVDAYVVILGDDAQVAANKLAEQWRDQVPEIRLQCHCGGGNMKKQLKRADKSGAQIALILGDDEITQEKVMVKYLRGQKEQESIEFTQVSSLLSELI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_NEUCR
Sequence: MAPANTLSAWSDLQSHHSKVGKTFVLKDAFKSDPERFSKFARTFTLPADISSDSPNATDILFDFSKNLVTEETLDKLVRLAEEAGVEKKRDAMFAGEKINFTEDRAVYHVALRNVSNQEMKVDGVDVMNTKGGVNEVLQHMKEFSEQVRSGEWKGYTGKKLTNIINIGIGGSDLGPVMVTEALKHYGAKDMTLRFVSNVDGTHIAEALAASDPETTLFLIASKTFTTAETITNANTAKSWFLEKTGGQGDITKHFVALSTNEAEVTKFGIDAKNMFGFESWVGGRYSVWSAIGLSVALYVGYENFHKFLAGAHAMDNHFRTAPLKENIPVLGGILSVWYSNFYNAQTHLIAPFDQYLHRFPAYLQQLSMESNGKSITSDGSAAKYTTGPIVFGEPCTNAQHSFFQLVHQGTKLIPADFILAAKSHNPISNNLHQKMLASNYLAQAEALMVGKTAEEVRAEGNVPEHLVPHKVFLGNRPTTSILVGGHIGPAELGALIVYYEHLTFTEGAIWDINSFDQWGVELGKVLAKKILKEIDEPGAGSGHDASTGGLLGAFKKYADF
What is the function of this protein?
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: EXOSX_MOUSE
Sequence: MAPPSPREHQSAPATSATKPDAEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEYDFYRSFPAFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDTNDVILERVGMLLDEASGVNKHQQPVLPAGLQVPKTIVSSWNRKAGEYGKKAKSETFRLLHAKNIVRPQLRFREKIDNSNTPFLPKIFVKPNARKPLPLALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELDHFTPPQSVLQRPKPQLYRAVGETPCHLVSSLDELVELNEKLLGCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIVDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLARHSLDHLLRLYCGVESNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDRMRLELWERGNHQPVQLQVVWQRSRDICLKKFVKPIFTDESYLELYRKQKKHLNSQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSENAAGVRKSGPLPSAERLENDLFGPHDCSHAPPDNYQNTSTDGTLPLQKQPSLFTEGKEETSVDAGCLLATAVITLFSEPNTEEGGKTPLTVAQKKAQNIMQSFENPFRMFLPSLEHKAHISQAAKFDPSSKIYEISNRWKLASQVQVQKEPKEATKKKVAEQTAAREEAKEEAAAGVLEQAIPVRQQAALENATKKRERATSDLRTIEQKQEKKRLKSSKKAKDPDPPGKDFSPYDYSQSDFRAFAGDSKSKPSSQFDPNKLAPSGKKGVGAKKCKQSVGNKSMSFAVGKSDRGFRHNWPKR
What is the function of this protein?
Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of MTREX, C1D and MPHOSPH6 with the RNA exosome involved in the maturation of 5. 8S rRNA.
What are the official names of this protein?
Exosome component 10, Autoantigen PM/Scl 2 homolog, Polymyositis/scleroderma autoantigen 2 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: GATB2_SYNAS
Sequence: MEYEPVIGLEVHAQLLTESKIFCGCSTKFGAAPNSHTCPVCLGMPGVLPVLNKKVVEFGMKMALATHCRINEECSFARKNYFYPDLPKGYQISQYAYPLAEFGYVDIEVEDGKKRIGLTRIHMEEDAGKLIHDPHNPSSYVDLNRTGVPLIEIVSEPDMRSAEEAAAYLRRLHEILVYLEICDGNMEEGSFRCDANVSLRPRGESEFGTRTELKNMNSFRNVQRALEYEIKRQQYILEGGGSVVQETRLWDDSQGVTHPMRSKEEAHDYRYFPDPDLVAVKISADWVEAVLREQPELPLEKRERFVRDYGIPPYDAGVLSSSRPLADYYEEVARQSGNPKAASNWVMGDLLRFLNEEKREIRDCPISAASLGELIRLIDQGTISGKMAKEIIEEMYRTGKTAPAVVEEKGMVQITDEAALSGVITGILEANPNQLAQYRSGRDKLFGYFVGQVMKATRGKANPQVINDLLKKMLAG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 2, Asp/Glu-ADT subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RL5_BURCH
Sequence: MARFQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAIADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGQAMYEFLDRFVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: COG6_NEOFI
Sequence: MESYFPPGATANHSSIRTSSPASTPLSPPTQRSNALSNRLTSVLSASYADSDIRDALETLSLRGVHNTAETRRQLRLDVQKEVVECNAEIVRDFGKVAEHIVRAKQDTAPVIEEASALMNQKKESETKQQLLDAFVKHFVVSDDDLLVLTSAEEPIDDRFFDVLDRVKQVHHDCEVLLGGENQRLGLELMEKSSRNLNSAYQKLFRWIQKEFKSLNLEDPRISSSIRRALRVLAERPSLFHSCLDFFADARDYALSDAFHYALTDAVSGSGGDRNVKPIEFSAHDPLRYVGDMLAWVHSTTVSEREALEALFVADGEEIAKGIQAGLSSEPWSRIDEGEEVSFDGQKALSDLVNRDLVGVSRALRQRVELVIQGHDEPVTCYKVVHLLSFYRATFSRLLGTKSNLADMMQTLENFTFARFESIMREQVNVLSNDHAALTPPDDLSAPEFFLDALEELTSLMKTHDASLGAEDAESESTADNKFTPVLRVAFDPFLQLAKSSAAELPDATARAIYTTNVLLTARSTISAFPFASATHLNPISTALSSLRMELLEIQHRYLLDASGLGVLLAALESFSPSPTTSKPESEGKDGHAPPQADRQPTDIAEIADLPAFQQEALIAVSQQLDDFLPSALMDATDNLKHLQSASFVQSVTEEAVEAFCRDFEFVEGMIIGADEARGRVHIKRTEDGSDAGVEDDVVTESGKVPDGDEQESGLRRLFPRTTGEIRVLLS
What is the function of this protein?
Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking.  COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 6, COG complex subunit 6, Component of oligomeric Golgi complex 6.
What is the protein family that this protein belongs to?
Belongs to the COG6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: WOX9_ARATH
Sequence: MASSNRHWPSMFKSKPHPHQWQHDINSPLLPSASHRSSPFSSGCEVERSPEPKPRWNPKPEQIRILEAIFNSGMVNPPREEIRRIRAQLQEYGQVGDANVFYWFQNRKSRSKHKLRLLHNHSKHSLPQTQPQPQPQPSASSSSSSSSSSSKSTKPRKSKNKNNTNLSLGGSQMMGMFPPEPAFLFPVSTVGGFEGITVSSQLGFLSGDMIEQQKPAPTCTGLLLSEIMNGSVSYGTHHQQHLSEKEVEEMRMKMLQQPQTQICYATTNHQIASYNNNNNNNNIMLHIPPTTSTATTITTSHSLATVPSTSDQLQVQADARIRVFINEMELEVSSGPFNVRDAFGEEVVLINSAGQPIVTDEYGVALHPLQHGASYYLI
What is the function of this protein?
Homeodomain transcription factor required for meristem growth and early development (PubMed:15753038).  Promotes cell proliferation and prevents premature differentiation in meristematic tissues during postembryonic development (PubMed:15753038).  Essential for maintaining tissue growth during embryogenesis (PubMed:17706632).  May act by repressing TSS to promote meristematic proliferation (PubMed:21185286).  Involved in the transcriptional activation of a subset of cytokinin response factors (PubMed:20110319).  May act as a negative regulator of cytokinin signaling in the dark (PubMed:21057190).
What are the official names of this protein?
WUSCHEL-related homeobox 9, Protein STIMPY.
What is the protein family that this protein belongs to?
Belongs to the WUS homeobox family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RAGE_MOUSE
Sequence: MPAGTAARAWVLVLALWGAVAGGQNITARIGEPLVLSCKGAPKKPPQQLEWKLNTGRTEAWKVLSPQGGPWDSVARILPNGSLLLPATGIVDEGTFRCRATNRRGKEVKSNYRVRVYQIPGKPEIVDPASELTASVPNKVGTCVSEGSYPAGTLSWHLDGKLLIPDGKETLVKEETRRHPETGLFTLRSELTVIPTQGGTHPTFSCSFSLGLPRRRPLNTAPIQLRVREPGPPEGIQLLVEPEGGIVAPGGTVTLTCAISAQPPPQVHWIKDGAPLPLAPSPVLLLPEVGHEDEGTYSCVATHPSHGPQESPPVSIRVTETGDEGPAEGSVGESGLGTLALALGILGGLGVVALLVGAILWRKRQPRREERKAPESQEDEEERAELNQSEEAEMPENGAGGP
What is the function of this protein?
Down-regulates receptor for advanced glycosylation end products (RAGE)-ligand induced signaling through various MAPK pathways including ERK1/2, p38 and SAPK/JNK.  Significantly affects tumor cell properties through decreasing cell migration, invasion, adhesion and proliferation, and increasing cellular apoptosis.  Exhibits drastic inhibition on tumorigenesis in vitro.
What are the official names of this protein?
Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted. SUBCELLULAR LOCATION: [Isoform 10]: Cell membrane; Single-pass membrane protein.
Protein: MSRA_LEIXX
Sequence: MTERAILAGGCFWGMQDLIRKRPGVLRTRVGYTGGDVPNATYRNHGSHAEAIEIEFDPSRIGYRDLLEFFFQIHDPSTANRQGNDVGASYRSAIFYEDEEQRRVAEETIAEVDASGLWSGKVVTEVSPAGPFWEAGPEHQDYLERIPWGYTCHFPRPGWTLPKREAAGD
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: MYX3_CRODU
Sequence: MKILYLLFAFLFLAFLSEPGNAYKRCHIKGGHCFPKGKICIPPSSDFGKMDCPWRRKCCKKGSGK
What is the function of this protein?
Cationic peptide that possesses multiple functions.  It acts as a cell-penetrating peptide (CPP), and as a potent voltage-gated potassium channel (Kv) inhibitor.  It exhibits antimicrobial activities, hind limb paralysis, and severe muscle necrosis by a non-enzymatic mechanism.
What are the official names of this protein?
Myotoxin-3, Crotamine-3.
What is the protein family that this protein belongs to?
Belongs to the crotamine-myotoxin family.
What are the subcellular locations of this protein?
Secreted.