PharMolix/UniProtQA huggingface dataset:
Protein: RL5_CALS4
Sequence: MSRLREKYEKEVVPALMERFGYKNIMQVPKLEKVVINIGVGEAKENPKALEAAMNDLMMISGQKPVITRAKKSISNFKIRKGMPIGVKVTLRRERMYEFLDKLFNIALPRVRDFKGVSPNSFDGRGNYALGVREQLIFPEIDYDKIDKVRGMDIIIVTTAKTDEEAKALLELLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PGSA_PSEFL
Sequence: MNIPNLITVLRVLLIPIFILLFYLPYNWSYMAASSVFAFAAATDWLDGYLARRLEQSTPFGAFLDPVADKLMVAVALVLLVQEHGNLWLTLPAAVIIGREIVVSALREWMAELGRTRPGGRCPTWANRKTAAQMLALVILLANPPAFTFWVLLGYAFLLIAGGLTLWSMLQYLRAAWPHLKTDGRKEIKLFESRG
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIB_SHEB2
Sequence: MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLAMQELGPVYIKLGQMLSTRRDLLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESLFDDFNEIPLASASISQVHTATLKSNGKDVVLKVLRPNVETKIQADLQLMSQTAKLIEYLLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLMVMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQLVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSSQQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGWRSRPKNRKF
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DDT4L_MOUSE
Sequence: MVATGSLSSKNPASISELLDGGYHPGSLLSDFDYWDYVVPEPNLNEVVFEETTCQNLVKMLENCLSRSKQTKLGCSKVLVPEKLTQRIAQDVLRLSSTEPCGLRGCVMHVNLEIENVCKKLDRIVCDASVVPTFELTLVFKQESCPWTSLKDFFFSRGRFSSGLKRTLILSSGFRLVKKKLYSLIGTTVIEEC
What is the function of this protein?
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
What are the official names of this protein?
DNA damage-inducible transcript 4-like protein, HIF-1 responsive protein RTP801-like, Soleus muscle atrophied after hindlimb suspension protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDIT4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLE_STAAC
Sequence: MNKNIIIKSIAALTILTSVTGVGTTVVEGIQQTAKAEHNVKLIKNTNVAPYNGVVSIGSGTGFIVGKNTIVTNKHVVAGMEIGAHIIAHPNGEYNNGGFYKVKKIVRYSGQEDIAILHVEDKAVHPKNRNFKDYTGILKIASEAKENERISIVGYPEPYINKFQMYESTGKVLSVKGNMIITDAFVEPGNSGSAVFNSKYEVVGVHFGGNGPGNKSTKGYGVYFSPEIKKFIADNTDK
What are the official names of this protein?
Serine protease SplE.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: YF015_YEAST
Sequence: MIKKSRTYYPSFGAYFHLLPAHPNAHSVTLLFGIFRSSPFLLLFLLIHRKVGEGRGSQRMKKKRGRANPSENLRERADPTNGPAENGKKGSVMCGCQLAVAMTTC
What are the official names of this protein?
Putative uncharacterized membrane protein YFL015W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RSGA_ECOHS
Sequence: MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIVISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHERTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLNKIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILESMAQVKTRKNFSDTDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFGM_COCIM
Sequence: MSVHTVMRTQVRSLAGMPKAAMRPLGNSFCARRYLSAAPLRSIPAAPTRLPLNRRWEPKRHSSSATAAAVLEQAAAQPETLSQDAIIESMDPAEAARISKVRNIGIAAHIDSGKTTSTERVLFYTGRIQAIHEVRGRDSVGAKMDSMDLEREKGITIQSAATFCDWVKKENGKDEKYHINLIDTPGHIDFTIEVERALRVLDGAVLILCAVSGVQSQTITVDRQMRRYNVPRISFINKMDRMGSNPFRAIEQINQKLKMHAAAVQVPIGLEDEFKGVVDIIRMKAIYNEGPRGEMVVEKDEIPADVRPVAEERRRMLIETLADVDDDIAELFLEEKEPTVEQLKAAIRRATIARTFTPVFMGSALADKAVQPMLDGICDYLPNPAEIENLALDQKRNEASVKLVPYNSLPFVGLAFKLEESNFGQLTYIRVYQGTLRKGTNVFNARNNKRIKVPRIVRMHSNEMEEVSEIGAGEICAVFGVDCASGDTFTDGQLNYSMSSMFVPEPVISLSIKPKNSKDLANFSKAINRFQREDPTFRVHFDTESEETIISGMGELHLDIYVERMRREYRVDCETGKPQVAYRETIGKRVEFDHLLKKQTGGPGEYARVAGWMEPTGNLDGNNFEEQITGGSISEKFLFACEKGFGLACDKGPLIGHKVLGTRMVINDGATHMTDSSEMSFKNATQQAFRKAFMDSQPHILEPLMKTVITAPSEFQGDVIALLNKRNAIINDTETGVDEFTVYADCSLNGMFGFSTHLRAATQGKGEYTMEFSHYEKAPGHLQKELIAEYEKAQAARHKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS14_STAAC
Sequence: MAKKSKIAKERKREELVNKYYELRKELKAKGDYEALRKLPRDSSPTRLTRRCKVTGRPRGVLRKFEMSRIAFREHAHKGQIPGVKKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RL2_XYLFA
Sequence: MPLIKFKPTSPGRRSAARVVTPNIHKGSPHAALLEPQSKTGGRNHHGRITVRHIGGGCKQRYRVIDFKRDKEAIPARVERIEYDPNRTAHIALLCYVDGERCYIIAPKGLKEGDKIISGPNVPIKLGNSLPLRNIPVGTTVHAVELKPSKGAQMARSAGSSVQLVAREGVYATLRLRSGEMRRVLAECRATIGEVGNEEHNLRKLGKAGAKRWLGVRPTVRGAAMNPVDHPHGGGEAKSGQGNPHPVTPWGVPTKGYKTRKNKRTQQFIIRGRRG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MEL_APIFL
Sequence: GIGAILKVLATGLPTLISWIKNKRKQ
What is the function of this protein?
Main toxin of bee venom with strong hemolytic activity and antimicrobial activity.  It has enhancing effects on bee venom phospholipase A2 activity.  This amphipathic toxin binds to negatively charged membrane surface and forms pore by inserting into lipid bilayers inducing the leakage of ions and molecules and the enhancement of permeability that ultimately leads to cell lysis.  It acts as a voltage-gated pore with higher selectivity for anions over cations.  The ion conductance has been shown to be voltage-dependent.  Self-association of melittin in membranes is promoted by high ionic strength, but not by the presence of negatively charged lipids.  In vivo, intradermal injection into healthy human volunteers produce sharp pain sensation and an inflammatory response.  It produces pain by activating primary nociceptor cells directly and indirectly due to its ability to activate plasma membrane phospholipase A2 and its pore-forming activity.
What are the official names of this protein?
Melittin, MEL, MLT.
What is the protein family that this protein belongs to?
Belongs to the melittin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Alpha-helical peptides form toroidal pores in the prey.
Protein: OPP27_HAEIF
Sequence: MKKTLAALIVGAFAASAANAAVVYNNEGTNVELGGRLSIIAEQSNSTIKDQKQQHGALRNQSSRFHIKATHNFGDGFYAQGYLETRLVSAQSGTESDNFGHIITKYAYVTLGNKALGEVKLGRAKTIADGITSAEDKEYGVLNNSKYIPIDGNTVGYTFKGIDGLVLGANYLLAQERYKYTTAAAAGAAGAAGAVAGEVYPQKISNGVQVGAKYDANNIIAGIAYGRTNYREDIASPDLGKKQQVNGALSTLGYRFSDLGLLVSLDSGYAKTKNYKDKHEKSYFVSPGFQYELMEDTNVYGNFKYERDSVDQGKKTREQAVLFGVDHKLHKQVLTYIEGAYARTRTTESKKGVKTEKEKSVGVGLRVYF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane protein P2, OMP P2.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: NHAA2_VIBVU
Sequence: MTKRKKRAAINLTRLPIEYIDWLSRPIYRFIHIESAAGIVLFISTLLAVLLANSHLSEEFARFWQISLGMTVGDLVFERSLHKWVNDAGMTLFFFLIALELKRELVLGELRNPQLALLSIAAALGGMSTPPLFYLLLQYGESGQHGWGTVMATDTAFVIGCLALLGRSIPSSLRIFMLSMAVVDDIGAIFVVAIGYGEAVDWLVLSYALLGFMLVRAMAFLGVRSLVLFSIVGGAIWLVIDMSGVHPTITGVILGLLTPTNKWMSRQHLFIIMEALVPSSPSQQWSGDKREGEILKTAAAAARETLSPVERLEMLLHPWVGFVVLPLFALANAGVSLTSVNLTSPITLAVFVGFVFGKPIGIVLFSWIAVWLGIAKLPENLNWGMVFGGGMLAGIGFTMALFISELAYNPDQINAAKLGIFIASITSALIGFLCLRYFAAREKQKRT
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KEFB_SALNS
Sequence: MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARVYGIRSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEKPWVEDDKPQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELIPEHSDMVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRF_DEHM1
Sequence: MINEILQKSEKKMAASLDVLSQELSGIRTGRSSPALVEHIKVEYAGVPTPINHLASIAAPDPRYITIQPWDRSCLSAIEKAIMKSDLGLMPNNDGNIIRLNIPPLSEERRQEMIKMVSKRLEEDKIAMRNVRRDAMDEMKKLEKSKEISQDDLKRGSDQLQKITDSFIAKADKLGADKETELKQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP1_ROTHI
Sequence: MATFKDACYHYKRINKLNHTVLKLGVNDTWRPSPPTKYKGWCLDCCQHTDLTYCRGCTMYHVCQWCSQYGRCFLDNEPHLLRMRTFKNEVTKDDLKNLIDMYETLFPMNQRIVCRFINNTRQHKCRNECMTQWYNHLLLPITLQSMSIELDGDVYYVFGYYDNMNSINQTPFSFTNLVDIYDKLLLDDVNFTRMSFLPASLQQEYALRYFSKSRFISEQRKCVNDSHFSINVIENLHNPSFKVQITRNCSELSFDWNKACKLVKKISAYFDILKTSHIEFYSVSTRCRIFTQCKLKMASKLIKPNYITSNHKTLATEVHNCKWCSVNNSYTVWNDFRIKNIYDNIFNFLRALVKSNVNIGHCSSQEKIYEYVEDVLNVCDDERWKTSIMEIFNCLEPVELDDVKYVLLNHEINWDVINVLVHSIGKVPQILTLENVIAIMQSIIYEWFDIRYMRNTPMVTFTIDKLRRLHTGLKTVDYDSGISDIE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.  Recognizes the host NF-kappa-B regulator BTRC through the presence of a DSGXS motif in the C-terminal substrate recognition domain.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: CTAA_CHESB
Sequence: MVAATEFPVSPMLTDAARRNRLWVRIWLYCVIVTLFAIVLVGGATRLTDSGLSITEWKPIHGVIPPLGEAEWAEEFARYQQIPEYEQINKGMSLEEFKGIFWWEWAHRLLARGVGFVFALPLLFFWVTGRLERHLKPKLLGILALGGLQGAVGWWMVASGLSERVDVSQYRLATHLTIACLIFNATMAVARGLAPHSGKPALDSTRRFAFWLVVAVLVQIYLGGLVAGLDAGMAYNTWPLMDGALVPQGLFEHRPAWVNLFENPKTVQFVHRLGAYVVLLLALWHAIATLRAEPDSTHARRAVLLFLLVCVQAAIGIATLLMVVPMDVALAHQAMALIVLGFATAHWRATRGAYPFMQAAA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEP3_ARATH
Sequence: MENLRNGEDNGSLIPFTFFDQSSVTIPLLKCSGLESSSSSSSSCDLSSSHSEEDESIDIKEEEEEEEEDGMTIEIKARGKNKTKPTPSSGKGGKHN
What is the function of this protein?
Elicitor of plant defense.
What are the official names of this protein?
Elicitor peptide 3.
What is the protein family that this protein belongs to?
Belongs to the brassicaceae elicitor peptide family.
Protein: RK9_ARATH
Sequence: MASSTALSLSWSSSPCWSHSFNGGANETLKVSERRFNFEVVSQKKAKKLRKVILKEDVTDLGKQGQLLDVKAGFFRNFLLPTGKAQLMTPLLLKELKMEDERIEAEKQRVKEEAQQLAMVFQTVGAFKVKRKGGKGKLIFGSVTAQDLVDIIKSQLQKDIDKRLVSLPEIRETGEYIAELKLHPDVTARVKINVFAN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9, chloroplastic, CL9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FLIP_ECOLI
Sequence: MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSFYS
What is the function of this protein?
Plays a role in the flagellum-specific transport system.
What are the official names of this protein?
Flagellar biosynthetic protein FliP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: CCA_SHESR
Sequence: MKIYLVGGAVRDSLLNLPIKDKDFMVVGATPEQMQQLGYRQVGKDFPVFLHPKTQQEYALARTERKVGLGYGGFSCYASPDVTLEQDLLRRDLTINAIAQDEAGNLHDPFHGIADIEARQLRHVSAAFSEDPLRVLRVARFAARFHGLGFEIAPETMALMQHMSQTEELTALTPERVWQEVDKSLGGPHPEVFFEVLRQCGALKVLFPEIDALFGVPQPEKWHPEIDTGLHTMMVLAQSSSMTEEKAVRFAALVHDLGKALSPKEHWPKHHGHGQKGLPVIKSLCERLRVPNEYRDLALLVSDQHQNVHQAFELRSETIIKLFDKADFWRKPERLKQLLLACIADMRGRTGFEHQPYPQSDYLNACFLAANNVDVKAIIAAGFQGAQIKQALNSKRIEVVEQVKLNWQQSQAKQTP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PDXH_VIBCH
Sequence: MDLSDIRREYIHGGLRRKDLQANPIDQFNLWLQQAIDANLSDPTAMTVATVDEHGQPFQRIVLLKNVDDAGFVFYTNLGSRKAQHIAHNNKISLHFPWHPLERQVHITGVAEKLTAMENMKYFMSRPKESQIAAIASHQSSRISARGVLEGKYLELKQKFANGEIPVPSFWGGYRIRPESLEFWQGGEHRLHDRFLYSRQDDNWTVDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: HIP44_ARATH
Sequence: MSSLIVKSLGSIVSIIARIFFFRRSRPVSNPRTTAHISYFRMSRKRPLSLQTVELKVRMCCTGCVRIVRNAISKLRGVDSVEVDKELGRVRVVGYVDRNKVLKAVRRAGKRAEFSPYPEPPLYFTSTQNYFVDPSKEFKESYNYYRHGYNGTEQHGNIPVGSRGDDRVSNMFNDDNVNACRLM
What is the function of this protein?
Heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 44, AtHIP44.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: CRI4_MAIZE
Sequence: MDHVPALVLAGCCFLALLPGWACGLGSMSSIAVSYGEDGPVFCGLNSDGSHLVACFGADASVLYGAPPNIPFLGLTAGDGFVCGLLLDTRQPYCWGSNSYVKSGVPQPMVEGARYSELSAGDNHLCALRAAQDGGRGSSAATSLIDCWGYNMTATHAVDEAVSTVSAGSVFNCGLFARNRTVFCWGDETVSGVVGLAPRDLHFQSIGAGGYHVCGVLENAQVFCWGRSLEMQQVVPSSAIGDGDVNIVPMDAMSTVVGGRFHACGIRSLDHQVACWGFTLHNSTSPPKGLKMYALVAGDYFTCGVPAETSLMPRCWGNSGPLALPMAVPPGICVPTACSHGYYEYVNHGEVGSIKVCKPANSRLCLPCSTGCPEGLYESSPCNATADRVCQFDCLKCVTDECLSFCLSQKRTKSRKLMAFQMRIFVAEIVFAVVLVLSVSVTTCLYVRHKLRHCQCSNRELRLAKSTAYSFRKDNMKIQPDMEDLKIRRAQEFSYEELEQATGGFSEDSQVGKGSFSCVFKGILRDGTVVAVKRAIKASDVKKSSKEFHNELDLLSRLNHAHLLNLLGYCEDGSERLLVYEFMAHGSLYQHLHGKDPNLKKRLNWARRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFEEGNIVEWAVPLIKAGDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDRPSMDKVTTALEHALALLMGSPCIEQPILPTEVVLGSSRMHKVSQMSSNHSCSENELADGEDQGIGYRAPSWITFPSVTSSQRRKSSASEADIVGRRATDGRNVGSSIGDGLRSLEEEIAPASPQENLYLQHNF
What is the function of this protein?
Putative receptor protein kinase.  Could play a role in a differentiation signal.  The CRINKLY4 (CR4) mutation affects leaf epidermis differentiation such that cell size and morphology are altered, and surface functions are compromised, allowing graft-like fusions between organs.
What are the official names of this protein?
Putative receptor protein kinase CRINKLY4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome, multivesicular body membrane; Single-pass type I membrane protein. Note=Also localized into protein export bodies.
Protein: EFG_MYCSK
Sequence: MAQKDVLTDLNKVRNIGIMAHIDAGKTTTTERILYYTGVNYKIGETHDGASTTDWMEQEQERGITITSAAVTCFWNDNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKMDKLGADFYFTVRTIEERLGATPLVIQLPIGAENDFIGIIDLVEMKAKVWRGETALGEKYEVEDIPAELADKADEYRTKLLEAVAETDEALLEKYFGGEELTVEEIKGAIRKLTVNSELYPVLCGSAFKNKGVQPMLDAVVDYLPSPLDVESVQGHVPNKEDELITRKPSVDEPFSALAFKIAVHPFFGKLTYVRVYSGTVESGSQVINSTKGKKERLGKLFQMHANKENPVERASAGHIYAVIGLKDTTTGDTLSDANQQIVLESMTFPDPVIEVAIEPKTKSDQEKLGTAIQKLAEEDPTFKVHLDQETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAYRETIKRKVEKVEFTHKKQTGGSGQFAKVLIDLEPFSGEDGATYEFENKVTGGRIPREYIPSVDAGAQDAMQYGVLAGYPLVNVKVTLLDGAYHEVDSSEMAFKVAGSQVLKKAAQAAQPVILEPIMAVEVTTPEDYMGEVIGDLNSRRGQIQAMEERAGARVVKAQVPLSEMFGYVGDLRSKTQGRANYSMVFDSYAEVPANVSKEIIAKATGQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APLP1_HUMAN
Sequence: MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
What is the function of this protein?
The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.
What are the official names of this protein?
Amyloid beta precursor like protein 1, Amyloid beta (A4) precursor-like protein 1, Amyloid-like protein 1, APLP, APLP-1.
What is the protein family that this protein belongs to?
Belongs to the APP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [C30]: Cytoplasm. Note=C-terminally processed in the Golgi complex.