PharMolix/UniProtQA huggingface dataset:
Protein: MUCAP_PIG
Sequence: ETARPSVAGSGTTGTVSGASGSTGSSSGSTGATGASIGQPETSRISVAGSSGAPAVSSGASQAAGTSGAGPGTTASSVGVTETARPSVAGSGTTGTVSGASGSTGSSSGSPGATGASIGQPETSRISVAGSSGAPAVSSGASQAAGTSGAGPGTTASSVGVTETARPSVAGSGTTGTVSGASGSTGSSSGSPGATGASIGQPETSRISVAGSSGAPAVSSGASQAAGTSGAGPGTTASSVGVTETARPSVAGSGTTGTVSGASGSTGSSSGSPGATGASIGQPETSRISVAGSSGAPAVSSGASQAAGTSGAGPGTTASSVGVTETARPSVAGSGTTGTVSGASGSTGSSSGSPGATGASIGQPETSRISVAGSSGAPAVSSGASQAAGTSEATTSIEGAGTSGVGFKTEATTFPGENETTRVGIATGTTGIVSRKTLEPGSYNTEATTSIGRSGTTHTDLPGGTTIVLPGFSHSSQSSKPGSSVTTPGSPESGSETGTSGEFSTTVISGSSHTEATTFIGGSGSPGTGSRPGTTGELSGTTIASGNATTEATTSTETRIGPQTGAQTTVPGSQVSGSETGTSEAVSNPAIASGSSSTGTTSGASDSQVTGSRTGTTGVVLGTTVAPGSSSTGATTGVLINEGTRSTSLGTTRVASGTTYESGTSNSVPSGGSGTPGSGINTGGSSTQVTGIQTGTTAVGFGSTLLPGSSNTGATTSPSERTSPGSKTGITRVVSGTTVASGSSNTGATTSLGRGETTQGGIKIVITGVTVGTTVAPGSFNTKATTPTEVRAATGAGTAVGATSRSTGISTGPENSTPGTTETGSGTTSSPGGVKTEATTFKGVGTTEAGISSGNSPGSGGVTSSQEGTSREASETTTAPRISATGSTSVSKEITASPKVSSPETTAGATEDQENENKTGCPAPLPPPPVCHGPLGEEKSPGDVWTANCHKCTCTEAKTVDCKPKECPSPPTCKTGERLIKFKANDTCCEIGHCEKRTCLFNNTDYEVGSSFDDPNNPCVTYSCQNTGFTAVVQNCPKQTWCAEEDRVYDSKQCCYTCKSSCKPSPVNVTVRYNGCTIKVEMARCVGECKKTVTYDYDIFQLKNSCLCCQEEDYEFRDIVLDCPDGSTLPYRYRHITACSCLDPCQQSMT
What is the function of this protein?
Apomucin is part of mucin, the major glycoprotein synthesized and secreted by mucous cells of the submaxillary gland.  Its highly viscous aqueous solutions serve to lubricate the oral cavity and to protect it from the external environment.
What are the official names of this protein?
Apomucin, Mucin core protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_CAMJE
Sequence: MANHKSAEKRARQTIKKTERNRFYRTRLKNITKAVREAAANGNKNAANEALKVANKSIHAMVSRGFIKKQTASRRVSRLALLVNKIA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: FLPA_THEKO
Sequence: MKVKKHRFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVVKFEGEEYRIWNPTRSKLGAAILNGLKNFPIKPGSTVLYLGVASGTTASHVSDIVGWEGKVFGVEFSPRVLRELVPLVEERRNIVPILGDATKPEGYRALVPKVDVIFEDVAQPTQAKILIDNAKVYLKSGGYGMISVKSRSIDVTKEPEQVFKEVEKELSTYFEVVERLSLEPYEKDHALFVVRKP
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: HLDD_DESVV
Sequence: MYIVTGGAGFIGSAMVWKLNEMGIEDIVVVDNLSTSEKWKNLVNRRYVDYVHRDTFMDMVLHGDLPWDVDAVVHMGACSATTERDADFLMENNLRYSRMLCELCMETGARFINASSAATYGDGSLGFSDDDATMLRLKPLNMYGYSKQLFDLWAYREGRLDGIASLKFFNVYGPNEYHKGDMRSVICKAYAQIGQEGVMRLFRSCHPDYADGGQMRDFIYVKDCVEVMWWLLQNPGVNGVFNVGTGKARTWNDLVTAVFRAMDREPVIEYIDMPEQLRGKYQSFTEATMDKLRDAGCPVRFTELEDGVTEYVRQYLAAADPFL
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: BAMC_VIBA3
Sequence: MKYSHQLVIGSLAVFVLTACSGSPTQRRQAKDDFEYLETPEFSQWQLPEDAQPQFYPNFDIPSGEFSGGTGRQVDIRPPQQVLELIPGARTERQNGEVTLWLLRAEEADRVWQTAVDMLTQRNIGIREQSENDIETDWVTWVSEDEEVEIGSRYSISRFQANNRHGFKINLIDWREGSEEKPVSATNKERYNAFLTNLVMARYDADLRAEAALKAQELVKRIPISMGSDRSGFPVIIARTPYNVLWQRLPTLLPTMGFELEERNQSQGTVKAKYAAPDDEFWEEIGLQPIDLAPGTYTFLFGDLGNRTSINVTDASGKPVEEELLKSMVPVLAHVADQTKDKKEAKSE
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamC.
What is the protein family that this protein belongs to?
Belongs to the BamC family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: TGT_BACLD
Sequence: MSQQPIRYEFIKACKQTGARLGRVHTPHGSFETPVFMPVGTLATVKTMSPEELKEMGADIILSNTYHLWLRPGHDIVKEAGGLHQFMNWNRAILTDSGGFQVFSLSEFRKIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPYPAEYDYMKKSVERTSRWAERCLKAHNRPDEQGLFGIVQGGEYENLRKQSAKDLISLDFPGYAIGGLSVGEPKDVMNRVLEFTTPLLPADKPRYLMGVGSPDSLIDGAIRGVDMFDCVLPTRIARNGTLMTSEGRLVVKNAKYERDFRPIDEQCDCYTCRNYSRAYIRHLIRCNETFGIRLTSYHNLYFLLKLMGQVRDAIREDRLGDFREEFFERYGFNKPNAKSF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: GATC_STRZP
Sequence: MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEVDTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: FIXU_RHILT
Sequence: MKAMIRRSGVGLSIYMSKKDVEEPVVAVENEDLWGGFILVRNGWLLGLPDLPQGTRLPITVEAMKQPDQD
What are the official names of this protein?
Protein FixU.
What is the protein family that this protein belongs to?
To K.pneumoniae and A.vinelandii NifT proteins and to the N-terminal of R.meliloti MosB protein.
Protein: GLYA_BACAN
Sequence: MDHLKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEHVNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDAESHCINYDDVLAKAKEHKPKLIVAGASAYPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGGMILCEEQFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIASLIAYTLKNHENEAALEEARKRVEALTSKFPMYTDL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_STAAW
Sequence: MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_BURL3
Sequence: MGNELQHRTVLLDEAVESLVTRPDGIYVDGTFGRGGHSRAVLARLAPGGRLIAFDKDPRAIETAQGIEDARFSIVHDSFASMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKALVARRAESDRLGPLDTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLVVISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRARSAVMRIAERVTP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1001R_ASFK5
Sequence: MVRLFYNPIKYLFYRRSCKKRLRKALKKLNFYHPPKECCQIYRLLENAPGGTYFITENMTNELIMIAKDPVDKKIKSVKLYLTGNYIKINQHYYINIYMYLMRYNQIYKYPLICFSKYSKIL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 100-1R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 100 family.
Protein: ILVC_HAEI8
Sequence: MANYFNTLNLRQKLDQLGRCRFMDREEFADEANFLKGKKIVIVGCGAQGLNQGLNMRDSGLDISYALRPEAIAEKRASFQRATENGFKVGTYEELIPTADLVVNLTPDKQHSKVVADVMPLMKKDSAFGYSHGFNIVEVGEEIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGLAIAKAWAAATGGHKAGVLESSFVAEVKSDLMGEQTILCGMLQAGSIVCYDKLVADGKDPAYAGKLIQYGWETITEALKQGGITLMMDRLSNSAKLRAFELAEQIKESLGFLYYKHMDDIISGHFSATMMADWANGDKDLFAWREATGKTAFENAPKYDGKISEQEYFDNGVLMIAMVKAGVELAFDAMVASGIYEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSNVATPILAKEIIPNLQKGDLGEPTPAVEIDNITLRDVNDAIRNHPVELIGQELRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: FHIT_DICDI
Sequence: MTTTYFGPWLIRQSEIFFTTELSFALVNLKPVLPGHVLVCPKRIVPRVKDLTKEEFTDLWLSAQRISSVVEEHFNGDGITFAIQDGKNAGQTVEHVHIHIIPRKKFDFENNDQIYNEIEKEREPRSYEEMEKESSELRPLFEENKNKTF
What is the function of this protein?
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP.  Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP.  Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival.  Plays a role in the induction of apoptosis via p53/TP53, SRC and AKT1 signaling pathways.  Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity (By similarity).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSD_HALSA
Sequence: MEATEQGPIDVEAVRADFPILEREVAGGEDLVYLDNAATSHTPEPVVDAIADYYRRYNSNVHRGLHELSQEASVAYEDAHDKLAAFVGGEDREEMVFTKNTTEAENLVAFAWGLNELGPGDEVVLTQMEHHASLVTWQQVADETGAEVKYIPITDDGHLDMDAAADMITDDTALVNAVHISNTLGTVNPVGELADIAHDHGAYIFVDGAQAAPTRAVDVQEIDADFYAFSGHKMLGPTGIGCLYGKRHLLAEMEPFLYGGDMIERVSYEDATWNDPPWKFEAGTPVIAQGIALAEAVDYLQDIGMDAIRAHEEALTEYAYDQLTMTDDVDVYGPPGDDRGAVVSFNVDGIHAHDLSSILNDYGVAIRAGDHCTQPLHDTLGVPASARASFYLYNTRDEVDALVAAVDEARQIFAP
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: A6334_ARTBC
Sequence: MLFTSTAVAALSGALLIQPALAAPNGLPSHGGSHHGPKDPFEVLDPQNWVNPDNMTWADFKSPPGTKWNDPSRKGSIRNFNIALVNVDYPDKPFTITMAPGSDVFKNPQPGSPNVTRSQVPAFYRDFLNKPGKLNRGHTLHEYWMEDSNGRFGVDLTTFGVYKMPLKSYQYGIGESMNAGACPIGETCYYEIRDDALGAWRKDIGEEKAKSFELVFILSAGQDESSTWQEFGEIMFQNKEDVTSAFGPPPGNGTGNMTLPNYAKTRYVEWTSWASASAIWPNAGDGSSTQAESSGMGTFAHELSHLLNVGDNYNNPYGKPLRRSYTGPWSMMSRGSFNGPGGPHTRWQVPPLQGGSMGSQHTFHDKIRLGLTTKDSALNISREALANSGLIVARVTARVIAPKPGDLIGIHVAMDKDKSPKCDVNTDPYCDGNGYQNYNVEVIDRMGADSFCPDSGVMLSKTRDKAFSNYQWTIDANPQDIKQVDFHRPDGTPAMISLGDYRQLADALFHAGTRSGSQYEYTDKANNLQFYIIEPHRDEAGVLSYTTAVRYVGGKDPHKRGVKLDKNAKITSSNTKPTDKGVTCSFTLHNTGTYNPAAGKAKHPQDVTAYLKSDVYRLKATVEGRGWRVEVPNALATAEFGKTVTVSVAVGAENSAQDKAKVTLTATSEADPSKFATAECKVNKFRN
What are the official names of this protein?
Putative secreted metallopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10B family.
What are the subcellular locations of this protein?
Secreted.
Protein: NOG2_SCHPO
Sequence: MGTYKKEKSRIGREGANEKKPGNLRVKGENFYRNAKDVARVNMYRGGKAKYNAAGELVRAAEFQSSEVPKARIQPDRRWFNNTRVIAQPTLTQFREAMGQKLNDPYQVLLRRNKLPMSLLQENTEIPKVRVLESEPFENTFGPKSQRKRPKISFDSVAELAKESDEKQNAYEEKIEERILANPDESDDVMLAARDAIFSKGQSKRIWNELYKVIDSSDVLIQVLDARDPVGTRCGTVERYLRNEASHKHMILVLNKVDLVPTSVAAAWVKILAKEYPTIAFHASINNSFGKGSLIQILRQFASLHSDKKQISVGLIGFPNAGKSSIINTLRKKKVCNVAPIPGETKVWQYVALMKRIFLIDCPGIVPPSSNDSDAELLLKGVVRVENVSNPEAYIPTVLSRCKVKHLERTYEISGWNDSTEFLAKLAKKGGRLLKGGEPDEASVAKMVLNDFMRGKIPWFIGPKGLSSSNDEINSSQKVATQQTEGSDQDGEEAEEEWHGISDDGKADESESTKPVAEGSASESTDESAVDDNKNRS
What is the function of this protein?
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
What are the official names of this protein?
Nucleolar GTP-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PLSY_HAES1
Sequence: MSLFAIIYMLFTYLLGSISSDVVICRFTERNDARVTNSNVLQKGEYRLVLVVFLCDVLKGMLPVWVGYYLGLTYFELGMVALAACLGHIFPIFFKFSGGKGVATAFGAIAPIAWGVAGSMLGTWLLIFLFSGYVALSTVVTALILPFYVWWFKPEFTFPVALVCCLLVYRHHENIQRLWRGQEDKIWSKFKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 1A1D_PARXL
Sequence: MNLQRFPRYPLTFGPTPIQPLARLSKHLGGKVHLYAKREDCNSGLAFGGNKTRKLEYLIPEVLAQGCDTLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIQMSRILGADVRLVPDGFDIGFRKSWEEALESVRAAGGKPYAIPAGCSDHPLGGLGFVGFAEEVRQQEAELGFKFDYVVVCSVTGSTQAGMVVGFAADGRADRVIGIDASAKPAQTREQITRIARQTAEKVGLGRDITSEDVVLDERFAGPEYGLPNDGTLEAIRLCARMEGVLTDPVYEGKSMHGMIEMVRNGEFPEGSRVLYAHLGGVPALNGYSFIFRNG
What is the function of this protein?
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.  Allows growth on ACC as a nitrogen source.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate deaminase, ACC deaminase, ACCD.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: CUTC_SHIBS
Sequence: MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLKSVRQWVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVDMPRMEKIMAAAGPLAVTFHRAFDMCANPLNTLSNLAELGIARVLTSGQKSDALQGLSKIMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSSDAHADEYSRYVVDGAAVAEMKGIIERHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRK_BACAH
Sequence: MMQKQNMIVVNQKEIAKNIYELVLQGTLVQQMNEPGQFVHIKVAEGIAPLLRRPISICNVDQEKNEFTMLYRAEGQGTKTLATRKQGEMVDVLGPLGHGFPVEEAEAGQTALLVGGGIGVPPLYELSQRLVAKGVRVIHILGFQTKDVVFYEEKFAELGDAYVATVDGTHGTKGFVTDVIDHYGIDFDILYSCGPLAMLRALEGRYKEKKAYISLEERMGCGIGACFACVCHLQEDPSGHSYKKVCSDGPVFPIGEVVL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: U17L6_HUMAN
Sequence: MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGSED
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, cell migration, and the cellular response to viral infection.  Seems to be non-functional in the regulation of apoptosis.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein 6, Deubiquitinating enzyme 17-like protein 6, Ubiquitin thioesterase 17-like protein 6, Ubiquitin-specific-processing protease 17-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GRPE_METSS
Sequence: MQEENQHPEQDDISEAQDAGAAGSLDARIAELEAQLAEQQANVLYVKAEGENIRRRAAEDIDKARKFALEKFSSELLAVKDSLDAALVVENATVESYKSGVELTAKQLLSVFEKFHITEINPLGEKFDPNKHQAISMLESDQEPNSVISVLQNVRPE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_PSETO
Sequence: MTVVLDTLVAVRRTAMDLLARREHGRVELTRKLRQRGAEPEMIETALDRLTEEGLLSEARYLESFVSYRPRSGYGPARIREELSQRGLQRADIDLALRECGISWQSQLEDTWRRKFSGHLPIDAKERAKQGRFLSYRGFSMDMISRLLSGRDLDD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFIP3_HUMAN
Sequence: MASAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYGAEQVKDLTKYLDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEEPDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLTPSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK
What is the function of this protein?
Acts as a regulator of endocytic traffic by participating in membrane delivery.  Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis.  Also required for the structural integrity of the endosomal recycling compartment during interphase.  May play a role in breast cancer cell motility by regulating actin cytoskeleton.  Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin.  Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
What are the official names of this protein?
Rab11 family-interacting protein 3, FIP3-Rab11, Rab11-FIP3, Arfophilin-1, EF hands-containing Rab-interacting protein, Eferin, MU-MB-17.148.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody. Note=In early mitosis remains diffuse and distributed through the cell. The onset of anaphase sequesters these vesicles to the centrosomes at the opposite poles of the cell. During telophase these vesicles move from the centrosomes, to the furrow, and then to the midbody to aid in abscission (PubMed:15158446, PubMed:15601896, PubMed:18511905). Interaction with Rab11 mediates localization to endosomes (PubMed:11495908). Interaction with ARF6 mediates localization to the midbody (PubMed:16148947).