PharMolix/UniProtQA huggingface dataset:
Protein: RS19_KOCRD
Sequence: MPRSLKKGPFVDQHLFVKVAKENEKGTKNVIKTWSRRSMIIPDMLGHTIAVHDGRKHVPVFITESMVGHKLGEFAPTRTFRGHVKDDKKGKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ATP6_HORSE
Sequence: MNENLFASFATPTMVGLPIVILIIMFPSILFPSPNRLINNRLISIQQWLVQLTSKQMMAIHNSKGQTWTLMLMSLILFIGSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVFMGFRHKTKAALAHFLPQGTPIFLIPMLVIIETISLFIQPVALAVRLTANITAGHLLMHLIGGATLALMSISPSTALITFIILILLTILEFAVAMIQAYVFTLLVSLYLHDNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RUVA_BORBR
Sequence: MIGRITGTLIEKSPPVVCVDVNGVGYEIDVPMSTLYALPETGARVTLFTHLVVREDAQLLYGFGSSAERSTFRELIKVTGIGARTALAVLSGLSVAELSQAITLQETGRLTRVPGIGKKTAERLLLEMRGKLGADIGATPHAASGHQSDILNALLALGYSDKESQAALKKLPDGVDVSEGIRLALKALVR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: YFCN_ECOLC
Sequence: MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPVKRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWLPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: ZIC5_XENLA
Sequence: MFGKDGRGGKIRTVSVDGLDCALMEPPLSKRSQTLRLADLAATQAHPHHNMTGFPGLGSHQSHSLPAHMHPGELGSDPGVALTPFGPEHMAQATALKLSPSAHPEAQTAAAFASPATVSYPVAHPHSGYSTSRDFILRRELSTSAMLGEQHPAAGSPHHHHHHHPHSMFISSTGSYAHPEGVGHPLFPAIHEQAAAGVHHPLNGQMRLGLAGELYGRPEAFRAEHYAASSLHHSYNSMNLNVNIAAAHPATAGAFLRYMRQPIKQELICKWIDQDQSSKKPCSKTFSTMHELVNHVAVEHVGGPEQSNHICFWEECAREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKVRGCDKSYTHPSSLRKHMKIHCKSPPGSPTNGSMGYPAVGTPLDDPLSPAQEQVRGRSSNLSPQVTNLNEWYVCQATGATVNMHTASSNADSSESEDDEETYRHSERTIR
What is the function of this protein?
May bind to DNA (By similarity).  Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate.  Does not induce anterior neural tissue.
What are the official names of this protein?
Zinc finger protein ZIC 5, XZic5, XlZic5, Zinc finger protein of the cerebellum 5.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS6_DICTD
Sequence: MRKYEIMCLISPELSEEDFKTLYEGIQQDIQNLGGEVQNVDVWGKRTLAYPVKKFTEGYYVVMNFLFPQTQLPEFERRLKLREKLLRYMITLLEKEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ACT_CRAVI
Sequence: KIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEAMFQPSFLGMESAGIHETSYQSIMKCDVDIRKDLYANIVLSGGTTMFPGIADRMQKEVTTLAPPTMKIKVIAPPERKYSVWIGGSILASL
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AMT15_ALTAL
Sequence: MATLLCDLQERSAKVERARHWDSKQGSSNSDVASGGSEVAGNSGNNSYLGDDVGWKIYPYRFLQLLQHLEQLQFTIQAPRHARLGISTVRMWSLRPYYNYDSYLEKDLIQPDVPHDSLIWALLRYVGRAVDRWVSRTFQPPRIRPLHANDPPAEASL
What is the function of this protein?
Part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (Probable).  AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), dehydroalanine, L-alanine which are common for all 3 AM-toxins I to III.  The fourth precursor is L-alpha-amino-methoxyphenyl-valeric acid (L-Amv) for AM-toxin I, L-alpha-amino-phenyl-valeric acid (L-Apv) for AM-toxin II, and L-alpha-amino-hydroxyphenyl-valeric acid (L-Ahv) for AM-toxin III (Probable).  AM-toxins have two target sites for affecting susceptible apple cells; they cause invagination of the plasma membrane and electrolyte loss and chloroplast disorganization (PubMed:22846083).  The non-ribosomal peptide synthetase AMT1 contains 4 catalytic modules and is responsible for activation of each residue in AM-toxin (PubMed:10875335).  The aldo-keto reductase AMT2 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV), one of the precursor residues incorporated by AMT1 during AM-toxin biosynthesis, by reduction of its ketone to an alcohol (PubMed:15066029).  The cytochrome P450 monooxygenase AMT3 and the thioesterase AMT4 are also important for AM-toxin production, but their exact function within the AM-toxin biosynthesis are not known yet (PubMed:17990954).  Up to 21 proteins (including AMT1 to AMT4) are predicted to be involved in AM-toxin biosynthesis since their expression ishighly up-regulated in AM-toxin-producing cultures (PubMed:17990954).
What are the official names of this protein?
AM-toxin biosynthesis protein 15.
Protein: FIXC_BRADU
Sequence: MIEERFDAIVVGAGMAGNAAALTMAKQGMKVLQLERGEYPGSKNVQGAILYADMMEKLIPEFREEAPLERHLIEQRFWMMDDRSHVGMHYRSEDFNEQRPNRYTIIRAQFDKWFSSKVREAGAIVLCETTVTELAQDDRNRVVGVRTDRRDGEIHADVVVLAEGVNGLLGTRAGLRARPAPDNVALAVKEMHFLPRETIEARFNLKGDEGVVIEAAGTISRGMTGMGFIYANKECISLGIGCLVADFQRTGQTPYGLLDEFKRHPSVAPLIAGSEVKEYSAHLIPEGGYKSIPQLYGEGWVVVGDAAQLNNAVHREGSNLAMTSGRIAAEAIGLVKSRGEPMSATNLSIYKKMLDDSFVIKDLKKYKDLPPLMHTHSENFFLTYPQLISKAMQNFVRVDGTPKVEKEKASLKSFVKTRSWSGLVGDAYRFARAWR
What is the function of this protein?
Could be required for the formation of a functional nitrogenase Fe protein.  Probably accepts electrons from FixA/FixB and reduces a quinone.
What are the official names of this protein?
Protein FixC.
What is the protein family that this protein belongs to?
Belongs to the ETF-QO/FixC family.
Protein: RP07_YLDV
Sequence: MVFQLICSTCGRDISEERYYLLIKELSLKKVLEGVKNNCCRLKLSTQIEPQRNLTVQPLIDIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: SSRP_STRPJ
Sequence: MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARINLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTGMTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL37A_MYXGL
Sequence: VGIVGKYGTRYGASLRKMVKKIEITQHSKYTCTFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTSSAVTVKSAIRRLREMKDQ
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L37a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYX_SALCH
Sequence: MQDITMEARLAELESRLAFQEITIEELNLTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: CITD1_SALPA
Sequence: MKINQLAVASTLESGDVMIRIAPLDTQDIDLQINSSIEKQFGEAIRATILEVLSRYDVRGVQLNVDDKGALDCILRARLETLLARASGIAALPWEDRQ
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein 1, Citrate lyase gamma chain 1.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETL_CITSI
Sequence: MPTITSYFGFLLAALTITSALFIGLSKIGLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FMT_CHRVO
Sequence: MKLIFAGTPEFAAAALRELIAAGHEIALVLTQPDRPAGRGMKLKPSPVKEVALAHGLRVEQPEKLRGNQEAQQMLRDIQADVMVVAAYGLILPQDVLDIPARGCLNIHASLLPRWRGAAPIQRAILAGDDETGITIMQMDVGLDTGDMLSIHPVAIAADETAATLHDKLAACGAQAIVETLGRLDRIVPRKQPEDGVTYAQKLSKAEAEVDWALPAEQVARAIRAYNPAPGAFTQLGGEPLKLWMASAEPGSAEPGAVVSADADGVLVGAGQGLVRVSVLQAAGGKRLAARDFVAGKSLPAGTRLGV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: AROC_LEPCP
Sequence: MSGSTFGLLFCVTNFGESHGPAIGCVIDGCPPGMALGEADIQPDLDRRRPGTSRHVTQRNEPDQVEILSGVYEGRTTGTPICLLIRNTDQRSKDYGNILDTFRPGHADYTYWRKYGLRDPRGGGRSSARMTAPMVAAGAVAKKWLREQHGITFTGWMSALGELPIPFEDESQIPLNPFYAPNAAVVPQLEAYMDALRKSGDSVGARIEVRARGVPAGLGEPLYDKLDADIAYAMMGINAVKGVEIGAGFASVAQRGTQHGDELTPAGFASNNAGGVLGGISTGQDLVVSIAIKPTSSIRSPKASIDRAGAPTVVETLGRHDPCVGIRATPIAEAMLALVVMDHALRQRAQCGDVQLPIPPLAAQAPRTETAPATPPLDAGDDIEA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: NAC54_ARATH
Sequence: MDVDVFNGWGRPRFEDESLMPPGFRFHPTDEELITYYLLKKVLDSNFSCAAISQVDLNKSEPWELPEKAKMGEKEWYFFTLRDRKYPTGLRTNRATEAGYWKATGKDREIKSSKTKSLLGMKKTLVFYKGRAPKGEKSCWVMHEYRLDGKFSYHYISSSAKDEWVLCKVCLKSGVVSRETNLISSSSSSAVTGEFSSAGSAIAPIINTFATEHVSCFSNNSAAHTDASFHTFLPAPPPSLPPRQPRHVGDGVAFGQFLDLGSSGQIDFDAAAAAFFPNLPSLPPTVLPPPPSFAMYGGGSPAVSVWPFTL
What is the function of this protein?
Transcription activator of STM and KNAT6.  Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation.  Required for the fusion of septa of gynoecia along the length of the ovaries.  Activates the shoot formation in callus in a STM-dependent manner.  Seems to act as an inhibitor of cell division.
What are the official names of this protein?
Protein CUP-SHAPED COTYLEDON 1, NAC domain-containing protein 1, NAC domain-containing protein 54, ANAC054, NAC domain-containing protein CUC1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HRPA_DICCH
Sequence: MGLSNAASLASMQTLDKAMASATAMTTAAQAQKVQTDAISSITDGQMDSASKAMNSGQKAAKAIQF
What is the function of this protein?
Major structure protein of the hrp pilus, which is a component of the type III secretion system (TTSS, Hrp secretion system) required for effector protein delivery, parasitism, and pathogenicity.  The hrp pilus functions as a conduit for protein delivery into the host cell (By similarity).
What are the official names of this protein?
Hrp pili protein HrpA, TTSS pilin HrpA.
What is the protein family that this protein belongs to?
Belongs to the HrpA type 2 family.
What are the subcellular locations of this protein?
Secreted. Fimbrium. Note=Extracellular and secreted via type III secretion system.
Protein: 28KD_MYCLE
Sequence: MPNRRRCKLSTAISTVATLAIASPCAYFLVYEPTASAKPAAKHYEFKQAASIADLPGEVLDAISQGLSQFGINLPPVPSLTGTDDPGNGLRTPGLTSPDLTNQELGTPVLTAPGTGLTPPVTGSPICTAPDLNLGGTCPSEVPITTPISLDPGTDGTYPILGDPSTLGGTSPISTSSGELVNDLLKVANQLGASQVMDLIKGVVMPAVMQGVQNGNVAGDLSGSVTPAAISLIPVT
What are the official names of this protein?
28 kDa antigen.
What is the protein family that this protein belongs to?
To M.tuberculosis ERP.
Protein: PMEA_ASPOR
Sequence: MHGSLLKLALLSFSLGSSAAVLPRDTGRTSAPSGCSTVGTSGDYSTIGDALTALGSSTADACIYIAAGTYEEQLVINYAGHLTLYGETTDTQTYKQNTVTITHTISSPEAGSLDNSATVNIKSDLVSVYNINIANGYGSGAQAVALVANADQLGFYACQFTGYQDTLYAKAGHQYYINSRIEGAVDYIFGDASAWFENCDIVSNGAGYITAMSRETTSDTAWYAIDHCNIKAASGVDLTGDVYLGRPWRVLARVIYQYSVLPDIINAKGWHSMADGATPLYYEFNNTGAGSDTSDREYLSTIDAPVTKETVLGDDYKNWVDLSY
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.
What are the official names of this protein?
Probable pectinesterase A, Pectin methylesterase A.
What is the protein family that this protein belongs to?
Belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_MSVK
Sequence: MSTSKRKRGDDANWSKRVTKKKPSSAGLKRAGSKADRPSLQIQTLQHAGTTMITVPSGGVCDLINTYARGSDEGNRHTSETLTYKIAVDYHFVADAAACPYSNTGTGVMWLVYDTTPGGQAPTPQTIFAYPDTLKAWPATWKVSRELCHRFVVKRRWLFNMETDGRIGSDIPPSNASWKPCKRNIYFHKFTSGLGVRTQWKNVTDGGVGAIQRGALYMVIAPGNGLTFTAHGQTRLYFKSVGNQ
What is the function of this protein?
Encapsidates the viral genome into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement.  The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).
Protein: Y143_CORK4
Sequence: MAEPDFNEIMAQAQQMQEELQRVQGEIAQSEISGSAGNGLVKVTMKGTGEVTNVTIDKSVVDPDDVDTLQDLVLGALQDANTALQSYAQEKMGPFSQALG
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein ckrop_0143.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: THI4_PYRNV
Sequence: MELKIARAIIKHGLEDLYEYSEVDVAVVGAGPAGLTAARYLAERGHRVVVYERRFSFGGGIGPGGNMIPKIVVQEEAVPVLKDFRVRYRPVGDGLYTVDPAELIAKLAAGAIDAGAKIILGVHVDDVIFRGDPPRVAGLLWVWTPIQMSGSHVDPLYTQARAVLDATGHDAEVISIASRKVPELGVEVRGEKSAWAEVSEKLVVEHTGRVAPGLYAAGMAVCAVHGLPRMGPIFGGMLLSGRRAAEIIHKDLVEYAVRA
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: RL5_KINRD
Sequence: MTTTTEARALPRLKQRYRDEIKGQLHEQFSYGNVMQIPGLTKVVVNMGVGEAARDSKLIDGAVRDLTAITGQKPQITKARKSIAQFKLREGMPIGCHTTLRGDRMWEFLDRLLSLALPRIRDFRGLSPKQFDGNGNYTFGLNEQSMFHEIDQDKIDRVRGMDITVVTTATTDDEGRALLRALGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SUMO1_PONAB
Sequence: MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV
What is the function of this protein?
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer.  Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4.  This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.  Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2.  Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1.  Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.  May also regulate a network of genes involved in palate development.  Covalently attached to ZFHX3.
What are the official names of this protein?
Small ubiquitin-related modifier 1, SUMO-1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Nucleus membrane. Nucleus speckle. Cytoplasm. Nucleus, PML body. Cell membrane. Nucleus. Note=Recruited by BCL11A into the nuclear body (By similarity). In the presence of ZFHX3, sequesterd to nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body (By similarity).
Protein: VIRBA_BARQU
Sequence: MKDEIDENNINDRSTIKDGQGKKLHSNTSKAVALLVLLGVCGYLAYSTLITNKKQPVELPKEAIIKQTERFRPAQPKPVLLEPTEKNNLLLPKVELPTPKRNQTNADDSLLEAAQRAPVLAYASPQKSQANAEKNNDTSPNQLERKPDETAQRFNHLLKPTNLEGIHASTLTNRNYIIAMGASIPCILETAISSDQQGFTSCIVSRDILSDNGRVVLLDKGTQIVGEYRSGLKKGQNRLFVLWNRAKTPSGVIITLASPATDALGRSGVDGDVDNHWFERIGSALLVSIVRDATNYARNRLPKDQDKNSSDTISSGPNIANIVVENYANIPPTLTKNQGEMVNVFVARDLDFSSVYKLKVIEDKKQIVNRSISRNFYKNSAVILK
What is the function of this protein?
Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function.
What are the official names of this protein?
Type IV secretion system protein virB10.
What is the protein family that this protein belongs to?
Belongs to the TrbI/VirB10 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DBP8_ASPCL
Sequence: MAPPRPEETISEDLDESSGSSETEQPDIQTRAPKRRRLSASSDDSYVAPAPLPTLSRIKKKGAEDAKPVASAGQENPVLIRDALEIGLREEASSFSALNVAPWLVGSLTTLAVRKPTAIQKACIPEILNGKDCIGGSRTGSGKTIAFSVPMLQKWAEDPLGIFGLILTPTRELALQIFEQIKAISAPQSMKPVLITGGTDMRSQALALAGRPHVVVATPGRLADHIKSSGEDTVCGLKRVRMVVLDEADRLLSSGPGSMLPDVETCLSALPPSSERQTLLFTATVTPEVRALKNMPRAANKPPVFVTEISSESQGTVPPTLKQTYLKVPLTHREAFLHVLLSTEGNSTKPAIIFCNHTKTADLLERMLRRLSHRVTSLHSLLPQSERNANLARFRASAARILVATDVASRGLDIPSVSLVVNYDVPRNPDDYVHRVGRTARAGRSGESVTLVGQRDVQLVLAIEARVGRQMEEWSEEGVSIEGRVVRTGVLKEVGEAKREASGEIDEGRDVLGRKRNKLKKVR
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.