PharMolix/UniProtQA huggingface dataset:
Protein: COQ4_XENTR
Sequence: MSGLLRYLHCSPAWRVLRPAAPGMQGGRFRSNYAAEEGIEEEIQFAAARQEDPSSLYSDHIPTNAVQKLLLSAGSAVMALYDPYRHDMVAVLGETTGAVALRKLRDQMRRDPEGLQILQERPRIRMSTLDFQTLREMPDGTFGREYARFLDVNHVTPDTRMPVKFVDDEELAYVAQRYREVHDLMHTLLGMPTNMLGEVVVKWFEAVQTGLPMCILGAAFGPLRLNNKRMKKLGVLVPWAVQSGRNARCVLNFYYEKRWGQSVASLREEIGILPPPEIKA
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: YGFZ_ECO57
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYLQGQVTADVSQMTDDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLAELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANIFSELPSKEKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLTGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLCIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_BROIN
Sequence: MEKFEGYSEKHKSRQQYFVYPLLFQEYIYAFAHDYGLNGSEPVEIVSCNNKKFSSLLVKRLIIRIYQQNFWDNSVNHPNQDRLLYYKNYFYSEFYSQILSEGFAILVEIPFSLRELSCPKEKEIPKFQNLRSIHSIFPFLEDKFLHLDYLSHIEIPYPIHLEILVQLLQYRIQDVPSLHLLRFFLNYYSNSNSFITSMKSIFIFKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLPLASSGTFLERIHFSRKMEHFWIMYPGFSRKNLWFFMDPLIHYVRYQGKAILASKGTFFLKKKWKCYHINLWQYYFRFWTQPRRIHINQLANSCFDFMGYLSSVPKSPLLVRNKMLENSFLIDTRMKKFDTIVPATLLIGYLSKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYHSGSSKKQTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSVFLEEFFTEEEQIFCLMFTKTTLFSFSGSHTERIWYLDIIRINDLVNPLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CLAJ_PENCR
Sequence: MKGPIVRITPNELHIKDASFYDEIYAGSGRIRNKDERFVKTFSAPHAMVSITDHAYHRVRRGLLGEFFSQRSVIKMEPIINGAIEKLSQRLHEACQTGAVINMDAAFAAMTADVITRHAWGQSGNYLDHGNFNKQWKDAVAGTMASRVLFRHFPYMLHILMAVPLPILLKLDPGVADILKIEGLVRRLSVENVNRGIVEKQEGKTIFDALNNVSVPPEQRTAKHLIDEGHILLLAGTETTAKALSTCLCYLLLAENKNVLLALQSELRQAFPNVSTWPKWTEAQKLPYLTAVINECLRLSHGLSTRLPRTAPKESLQYKQWHIPAATPVSQTAYFVHMDPSIFPDPERFEPERWIRASKEGLHLERYIVSFSKGSRQCLGINMAYAEIFLALTHIMRNFEFQLHDTSVDDVRLFRDRFFGAAQDGSVGVRVLVNEVKY
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the cla gene cluster that produces clavatol and ortho-quinone methide (PubMed:30811183).  The clavatol biosynthesis cluster cla and the terrestric acid cluster tra are both involved in the production of peniphenones and penilactones (PubMed:30811183).  The non-reducing PKS claF is responsible for the formation of clavatol from successive condensations of 3 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit, and 2 methylation steps (PubMed:30811183).  The esterase claE probably collaborates with claF by catalyzing the hydrolysis of ACP-bound acyl intermediates to free the ACP from stalled intermediates (By similarity).  The clavatol oxidase claD then converts clavatol to hydroxyclavatol (PubMed:30811183).  Spontaneous dehydration of hydroxyclavatol leads to the accumulation of the highly active ortho-quinone methide (PubMed:30811183, PubMed:31860310).  On the other hand, the PKS-NRPS hybrid traA is involved in the formation of crustosic acid, with the help of traB and traD (PubMed:30811183).  The polyketide synthase module (PKS) of traA is responsible for the synthesis of the polyketide backbone via the condensation of an acetyl-CoA starter unit with 3 malonyl-CoA units (PubMed:30811183).  The downstream nonribosomal peptide synthetase (NRPS) module then amidates the carboxyl end of the polyketide with L-malic acid (PubMed:30811183).  Because traA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase traG (By similarity).  Crustosic acid undergoes decarboxylation and isomerization to the terrestric acid, catalyzed by the 2-oxoglutarate-dependent dioxygenase traH (PubMed:30811183).  Both acids are further converted to the 2 gamma-butyrolactones (R)-5-methyltetronic acid and (S)-5-carboxylmethyltetronic acid, with involvement of the cytochrome P450 monooxygenase claJ (PubMed:30811183).  Spontaneous addition of the methide to these gamma-butyrolactones leads to peniphenone D and penilactone D, which undergo again stereospecific attacking by methide to give penilactones A and B (PubMed:30811183, PubMed:31860310).
What are the official names of this protein?
Cytochrome P450 monooxygenase claJ, Clavatol biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: V2R_BOVIN
Sequence: MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQRDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPVPRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATASSFLAKDTPS
What is the function of this protein?
Receptor for arginine vasopressin (PubMed:7698346, PubMed:8257689).  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Involved in renal water reabsorption (By similarity).
What are the official names of this protein?
Vasopressin V2 receptor, V2R, AVPR V2, Antidiuretic hormone receptor, Renal-type arginine vasopressin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein: ADDA_STRGC
Sequence: MRKKSFLSPEEISQLQHFEATSSKEQKRTAEQIEAIYSSGQNILVSASAGSGKTFVMVQRIIDQILRGVSIQELFISTFTVKAAGELKERLEKELSKVLKESQDEELKQHLAKQLAAIATADIGTMDSFTQKLLNKYGYLLGLAPNFRILQSASEQTMLQNEVFQQLFEQYYTGEQKEIFEKLVKNFTGKKKNISGFRQQVYAIYQFLQSTSNPQRWLQDFFLKGYEETDFSRERDKILQQVKGALFDLEDYFRFHLDNEGREFAGAKYQENVLLALDKLGSLQELSSEQDYFRVLKDVVLLSRASGGRALTITTRKEELKELADTFNQGRKERIEHLRGLESSIYQFEFLEKYQDDSLPLLDLLRDFMSDFTQTYLERKKTENAFEFGDISHFAIQILEDFPQVRSFYQERYHEVMVDEYQDTNHTQERMLELLSNGYNRFMVGDIKQSIYRFRQADPQIFNDKFRLYQADPSQGKLIVLKENFRSHVEVLEATNDVFKRLMDEQVGEINYDETHYLVAGNPTKASPDPKNRAEFLLYDSTVASEELSEESISAGEVSLVIKEIIRLHEEEAVAFKDITLLTASRTRNDIILAEFAKHNIPLVPDGGEDNYLQSVEVMVMLDTLRTINNPLNDYALTALLKSAMFDFGEDELARIALQKSQEKSQENLYEKLENALTNQGLHPDLILPDHKKKLELFQKTLLSWRTFAKTHSLYDLIWKIYQDRFYYEYVGALPNGAQRQANLYALSLRANDYEKSSFKGLSRFISMIDKILENQHDLASVPYAAPQDAVHLMTVHKSKGLEFKYVFLLNMDKAFNRQDTSSSIILSRKNGIGIKYIADVEVEYPEKVKPRSIRLSMDTLPYQQNLEEIKLASLSEQMRLLYVAMTRAETKLYLVGKGSQEKLEKRSWGQAEQGLLSASIRSQTTSFQDWLYAIQTVFSEDQLAFDLRFVRDEDLTADKIGQIHHSNPFDADDLTDNRQSEDIGRALDILESVDRLNSQYRSAIELPSVRTPSQIKKFYEPIMDTEGMDIIDERVAFRPQPNFDLPDFSRKAKVTGAQVGSAVHELMQRIPIDQKPDMAVLKLSLKQVQAEESVKKQIDLNKIASFFETRLGEILLANSDKLHREAPFAMFKRDEISGQDFVLRGILDGYLLFEDRIILFDYKTDKYKEASELIARYHSQLDLYAQALSRSYGISQIEKYLILLGGEQLQVVQVD
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: THIC_ALIFM
Sequence: MSSSRKQARLDAKTNIESLSVQPYPNSNKVYIEGSRPDIRVPMREISLADSLVGGTKESPIFEPNEPIQVYDTSGVYTDPSYDIDVYRGLPKLRQEWIEERNDTELLDGVSSVYSQERLADETLDELRYGNLPTIRRAKQGQCVTQLHYARQGIITPEMEYIAIRENMGRQKFADEQLNHQHPGHSFGANLPKEITPEFVRKEVAEGRAIIPSNINHPEAEPMIIGRNFLIKVNANIGNSSVSSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLNWEVMRDTLIEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSVADANDEAQFAELRTLGELTKVAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKTGLITYKLAAHAGDLAKGHPGAQIRDNALSKARFEFRWEDQFNLSLDPITAREYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDSEQVALDQAIEIKMIDDPLEGMRQKSEEFKASGSELYHPAVEAE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y365_METJA
Sequence: MAKAIIDIETTGLNPMEHRIVAIGVKLGDRDIILMDESEYYLLVNFWDTVEKEGIEKIIGFNIDFDWQFLKLRSLYHRLKIKHFRKYQGRVDLRQILNGSGGQYRKGTKLVDYCRFLGIDVPEDDANGSEIPELWEKFEEEGDEEAKRKICEHLKRDLERTWELYKILVDCGLIEE
What are the official names of this protein?
Uncharacterized protein MJ0365.
Protein: SYS_CHLT3
Sequence: MLDIKYVRENPDAVKKMLEMRLLASESKKIDELIRYDSERKAKVTESDTLKAMRNSVTQEIAKIKREKTGSADELIAEMKIVSDRISEIDAELREIETKQEELLLAVPNILHESVPEGKSAADNVVYKEVMDCKREFDFKPKDHIELGKSLGMLDFERGAKIAGAGFPLYIGKGASLERALINFMLDLHLEKHGYKEVFPPFFVNRDSLRGTGQWPKFADQVYYMNDDDIYAIPTAEVPVTNMHRDEMLQSKELPIKYAAYSACFRREAGSYGKDTKGFLRVHQFNKVEMVKFVLPETSYDELEALLGDAEDVLKALEIPYRVLLLCSGDISANAAKCYDIEVWSPAEEKFLEASSCSNFEDYQARRAQIRFRRQPKAKPEFVHTLNGSGLATSRLMVSLMENYQTPDGKIQVPKVLQKYMGCEVIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TREA_XANCP
Sequence: MPHAPARSGDAMSAAAPPCCTSLLGLSLSMFVAPCALAATPLEGAVVSAPAPTPPTPDLAYPELFQAVQRGELFDDQKHFVDFLPLRDPALINADYLAQHEHAGFDLRKFVDANFEESPPVQTDAIRQDTALREHIDALWPKLVRSQTNVPAHSSLLALPHPYVVPGGRFREVYYWDSYFTMLGLVKSGETTLSRQMLDNFAYLIDTYGHIPNGNRTYYLSRSQPPLFSYMVELQAGVEGEAVYQRYLPQLQKEYAYWMQGGDDLQPGQAARHVVRLADGSVLNRYWDERDTPRPEAWLHDTRTAAEAHDRPAADVYRDLRAGAESGWDYTSRWLADGKTLSTIRTTAIVPIDLNSLLYHLERTLAQACAHTGTACSQDYAALAQQRKQAIDAHLWNAAGYYADYDWQTRTLSNQVTAAALYPLFAGLASDDHAKRTATSVRARLLRPGGLATTALKTGQQWDEPNGWAPLQWVAVDGLRRYGEDGLARTIGERFLTQVQALFAREHKLVEKYGLDADAAGGGGGEYALQDGFGWTNGVTLMLLNLYPSQGATQAPAKTKRKPEPAAP
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TH12_TRYBB
Sequence: MTERRDNVSHAPDAIEGPNDGAHAEETSPGFFSFENLGVAQVQVVGGTLNGYVIGYVAVYLLLYLTATECKFTTEGACGGRKIYGCKWSGTTCKFENPKCSEGSDPSDSCKNEVAYTSVYSGIFACAMIVGSMVGSIIAGKCITTFGLKKSFIIVSITCTIACVVVQVAIEYNNYYALCTGRVLIGLGVGILCSVFPMYVNENAHPKLCKMDGVLFQVFTTLGIMLAAMLGLILDKTGASKEEANMAGRLHVFSAVPLGLSVAMFLVGMFLRESTATFAQDDDGKADGGMDPNEYGWGQMLWPLFMGAVTAGTLQLTGINAVMNYAPKITENLGMDPSLGNFLVMAWNFVTSLVAIPLASRFTMRQMFITCSFVASCMCLFLCGIPVFPGVAEEKVKNGVATTGIALFIAAFEFGVGSCFFVLAQDLFPPSFRPKGSSFVVMMQFIFNILINLLYPITTEAISGGATGDQDKGQAVVFILFGLIGLICFVLQFFYLYPYDANQDHENDHGTEPVERILSPVDVPTPRN
What is the function of this protein?
Facilitative glucose transporter.
What are the official names of this protein?
Glucose transporter 1E.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TXJ05_LYCSI
Sequence: MSPKVQALIFIVGLITLLAAHAQEELSDNIESERGCSGAYKRCSSSQRCCEGRPCVCSAINSNCKCRKTYTELFKEYFEK
What are the official names of this protein?
U19-lycotoxin-Ls1a, U19-LCTX-Ls1a, Toxin-like structure LSTX-P5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family. 05 (U19-lycotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FAF2_ASCSU
Sequence: KHEYLRF
What is the function of this protein?
Has effects on muscle tension.
What are the official names of this protein?
FMRFamide-like neuropeptide AF2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIG_CLOB8
Sequence: MKKDVLTLGGHEFSSRFILGSGKYNLNLIKAAVENAGAQMITLALRRANTSGGENILDFIPEGVTLLPNTSGARNAEEAVRIARLARAMNCGDFVKVEIIHDSKYLLPDNYETIKATEILAKEGFIVMPYMHADLNVARDLVNAGAACIMPLASPIGSNKGLATKEFIKILVDEIDLPIIVDAGIGRPSQACEAMEMGVAAVMANTAIATAGDIPAMAGAFKQAIEAGRAAYLSGLGRVLDKGASASSPLTGFLED
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C516A_DICDI
Sequence: MIILLLSIIIFILYIVKIFKNKSCCGNEIILPPGPISLPFIGNLHQLAIDPHLAIQKLMFKYGNVMTVYFANIKTVVISDPNYLKEVFVNQSHKTSDRYLMGTSRIIGNEKDILFSNGQYWKNYRQILAQSFLKLRDHKGITEKISLESVKLSQAFEWYATSGQVVNPCSLFKMYTLNVIMQLLYSHRSSYDLKGQHPIIDALKMVEESLAVGNVLDLFPILNIFLKKNKLKLVNNLQQVWSYSQDSIKEHREKLLINPEKIDDLLDLFINEIKLSKNSEFFDDEGLYRVCSDLLLSGTETSSSTMSWLLLFLINNPNFQDKVRTELLEATGGKKTIGLTEKSKTPFFNACIKEALRIRPVGALSLPRIASEDVTCGPYTIEKGSQIIMNVYGLAMDPTVWEDPETFNPYRWLSSDISQSTYSFIPFGCGSRVCVGSSLARDEIFLGIGNILLNYIFESQNGKPINEKGHFGIALQTVDYNVKLTKI
What are the official names of this protein?
Probable cytochrome P450 516A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VGE6_EHV2
Sequence: MEEMRHAGQISRKLLFYFGSDNYNLSINDSMFRNCTLRADRAAALFGTMLEGVFLGIVLTMMGFFSVKTRFTPSSNIWLFAGCVAIALWLMTKMAQDYAPGPLKCIVTENLALFCSLLGGALNVGMCVDRCRAVYSRMARGSMTPAAICTYIFWAVVGSLLVIAVNALEMSRNGLHMSEGLEGGCFQAASPLAHRAKLVAKFLMYLVFVCIVSVGTALTLVKILNTNLNRKRAICVNVVLVTLPNTFIWLTAMTSAWREFSSYKMCPKIVTGNVFIYLSSVPMLVILFVYMFTGKNLKHTLRPQTRSYSSSTGSASCFAHLAGKP
What are the official names of this protein?
G-protein coupled receptor E6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: 50510_ASFWA
Sequence: MFSLQELCRKNIYILPYPLGKHVLQQLGLYWKGHGSLQRIGDDHVLLQQDLIFSINEALRMAGEEGNNEVVKLLLLWEGNLHYAIIGALEGDRYDLIHKYYDQIGDCHKILPLIQDPQIFEKCHELSNSCNIRCLLEHAVKHDMLSILQKHREQIRLHLALTQILFELACHERKNDIIRWIGYSLHIHHLETIFDVAFAHKNLSLYVLGYELLMHKVNTEAAYIELPNLLSYHLRTAAAGGLLNFMLETIKHGGYVDKTVLSAAIRYKHRKIVAHFIHQVPRKTVKKLLLYAVQARAPKKTLNLLLSSLNYSVHTITKQLVHNVVIYSSTLVVKLLLMRRKNKLNLVDAVLARLVKYSTYTDIVQFMSEFSVSPERVIKMAARESRTFLIEMISKAAWGNHPQTLIHHLKQLAHTMKSQSGKDLIIYTIHYIYLNSNMLVAEEEKNIFKLAKFYANHNAVNRFKQVCEDYYALDVDARFKTLILECFEIAVQKNYPRIANIVDDYVRFLFYRGDITEEEIHEAYSLKDAEFYVDLKWLQHDLF
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-10R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: DCUP_CORGL
Sequence: MSALTIPAARRTLNNAPIIDAANGKTPTRTPVWFMRQAGRSLPEYKKVREGISMLDSCFMPELLAEITLQPVRRHDVDAAILFSDIVVPLRAAGVGVEIVAGRGPVLDAPVRSRGDVLNLPILEGNVPEVEQGIGIILDELSDSQALIGFAGAPFTLASYLVEGGPSKNHEKTKAMMHGDPETWHALMARLVPTIVNSLKSQIDAGIDAVQLFDSWAGFLTERDYTEFVLPYSTEILEEVGKYQLPRIHFGVGTGELLGAMSKAGSEVMGVDWRVPLDKAAERIAAVSGPKVLQGNLDPALLFAGRAPLTKEIERIKAEAQTAVDAGHATGHIFNLGHGVLPNTVAEDITEAVSIIHS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK12_NEOYE
Sequence: MSTKVENILEELKSLNLLEAAELVNTIEETFDVDASAASGGMMMATPTSAPASAEVEEKTEFDVVLEEVPAPKKISVLKVVRPLTGLGLKEAKDLVESTPKVLKEGASKDDAETMKKQLEDAGATVIVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PHOSP_RABVI
Sequence: MSKIFVNPSAIRAGLADLEMAEETVDLINKNIEDNQAHLQGEPIEVDNLPEDMRRLHLDDEKPSGLGGMAKAGEVKYREDFQMDEGEDPNLLFQSYLDNVGVQIVRQMRSGERFLKIWSQTVEEIISYVTVNFPNPPGRSSEDKSTQTTGRELKKETTSASYQRDSQSSKARMAAQTASGPPALEWSATNEEDDLSVEAEIAHQIAESFSKKHKFPSRSSGIFLYNFEQLKMNLDDIVKEAKNVPGVTRLAHDGSKLPLRCVLGWVGLANSKKFQLLVEPDKLNKIMQDDLNRYTSS
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA.  Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus.  Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body (By similarity).  Inhibits interferon induction pathways by interacting with host TBK1 and preventing the formation of dynamic cytoplasmic condensates that have liquid properties and that are essential for interferon production (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus protein P family.
What are the subcellular locations of this protein?
[Phosphoprotein]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Isoform P2]: Host cytoplasm. SUBCELLULAR LOCATION: [Isoform P3]: Host nucleus. SUBCELLULAR LOCATION: [Isoform P4]: Host nucleus. SUBCELLULAR LOCATION: [Isoform P5]: Host nucleus.
Protein: TPIS_STRT2
Sequence: MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSADLVEAGIAVPAVDLTTVIAAAKGSNLKVAAQNTYFENSGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFANGMIPIICCGESLETYEAGKAAEFVGAQVSAALAGLTPEQVASSVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVLYGGSVKPENVAEYMACPDVDGALVGGASLEPESFLALLDFVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_VIBC3
Sequence: MLLNTLSPAAGSKHAPKRLGRGVGSGLGKTGGRGHKGQKSRSGGKVRPGFEGGQMPLKQRLPKFGFTSRKSFVSAEVRLSELAKVTGDVVDLNALKAANLVTKNIEFAKIVLSGEISKAVTVKGLRVTKGAKAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TRMD_GEODF
Sequence: MKFDVLTLFPGMFEGPLTESILKRAREKGLIDVALHNIRDFAFDRHSVTDDYPYGGGAGMVMKVEPLAACVEHAQAGSPEARVILTTPHGRPFSHAVAAELAREEALIIICGRYEGVDERVRELFVDDEISLGDFVLTGGEMAAMVIIDAVSRLVPGVLGSEESAINDSFADGLLEYPQYTRPSEFRGLEVPKVLLSGNHQEIEMWRRHKSLEATALLRPDLLQSAKLTNGDRKYLEKSSKDAR
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAL1_ATEGE
Sequence: MDKPRKENEEEPQSAPKTDEERPPVEHSPEKQSLEEQSSEEQSSEEEFFPEELLPELLPEMLLSEERPPQEGLSRKDLFEGRPPMEQPPCGVGKHKLEEGSFKERLARSRPQFRGDIHGRNLSNEEMIQAADELEEMKRVRNKLMIMHWKAKRSRPYPI
What is the function of this protein?
May be involved in transcriptional regulation.  Modulates various viral and cellular promoters in a promoter context-dependent manner.  Does not bind DNA directly (By similarity).
What are the official names of this protein?
Transcription elongation factor A protein-like 1, TCEA-like protein 1, Transcription elongation factor S-II protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family. TFA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HAPP_PHYPO
Sequence: MMKYVFVALCLFAVVALATEVEQKESNTRVARLNVGGLVGCVVALVANIVGGLLRVIIGLVVTLSGVLQIVVGTVLGLVATVASLALDVVGSTVGGILNSLLGLGAILSLVEEVLHVLLSQALLTGLVNAIFALPLSLLVALSTLTDALASAACDCGASATGAGSSLAGCIAGPNGLLFTVGAGASV
What are the official names of this protein?
Plasmodium-specific hydrophobic abundant protein, HAP-P.
What is the protein family that this protein belongs to?
To HAP-S protein.
What are the subcellular locations of this protein?
Membrane.
Protein: APC13_BOVIN
Sequence: MDSEVQRDGRILDLIDDAWREDKLPYEDVAIPLNELPEPEQDNGGTTESVKEQEMKWTDLALQYLHENVPPIGN
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 13, APC13, Cyclosome subunit 13.
What is the protein family that this protein belongs to?
Belongs to the APC13 family.
What are the subcellular locations of this protein?
Nucleus.