PharMolix/UniProtQA huggingface dataset:
Protein: ST_POVJC
Sequence: MDKVLNREESMELMDLLGLDRSAWGNIPVMRKAYLKKCKELHPDKGGDEDKMKRMNFLYKKMEQGVKVAHQPDFGTWNSSEVGCDFPPNSDTLYCKEWPNCATNPSVHCPCLMCMLKLRHRNRKFLRSSPLVWIDCYCFDCFRQWFGCDLTQEALHCWEKVLGDTPYRDLKL
What is the function of this protein?
Promotes efficient viral genome replication by modulating several host signaling pathways including transport network, interferon production or cell cycle progression (PubMed:20485545, PubMed:33092197, PubMed:33849980).  Inhibits host PP2A phosphatase activity and thereby prevents agnoprotein dephosphorylation (PubMed:20485545, PubMed:18353419).  Inactivation of PP2A also results in the transactivation of cyclin A and cyclin D1 promoters (By similarity).  In addition, antagonizes the RIGI-mediated IFN response through interaction with E3 ligase TRIM25 leading to the inhibition of 'Lys-63'-linked ubiquitination of RIGI.  Inhibits nucleotide excision repair (NER) pathway which leads to DNA strand breaks during DNA replication and micronuclei formation (PubMed:25744060).
What are the official names of this protein?
Small t antigen, ST, ST-AG.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MRAZ_ACET2
Sequence: MFYGEYQHSVDAKGRVIIPSKFREGLGEKFILTKGLDNCLFAYSLEEWSNLEAKLRSLPFTDKDVRAFVRFFFAGAAEVEVDKQGRILIPQNLREYAGLEKDVYIIGVSTRVEVWDKSKWESYSGDENMSAESIAEKMAMLGI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS17_CAMJE
Sequence: MAFKREIQGVVVKIAGEKTASVLVERKVVHPRYRKIVKRFKKYLIHDERNEVKVGDTVVAVECRPLSKRKSFRLKSVLATGVE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NUOCD_SULSY
Sequence: MAWISLEKAKKLEERFGYPKVSEGKGVLSVEVPKDKFIEFLTFLKEDPEYQFKMFIDLTIIDHGEKENPRFQGVVILFSPKNQERIIVKTWAENETLPTLTNLWKGAKWAEREAWDMFGIKFEGHENLVRMLLWETYPYHPLRKDFPLEGIKDTELPSLNETLRGENLEGLFNYDRMHTALPTMEDLEITQKKRMPVKTSQIVLNWGPLHPGTHGTIWFLFDLDGEYVKQCDIIIGQLHRGVEKLGENVNWQQFIPYTDRMDYIAAINENHAYVLAAEKMLGIEVPEKAKWIRTMMAELSRINSHLLWLGTYALDLGALTMFLYTFREREKIMDIIEGITGARFTINYFRIGGVFADLPYGALDAIEHLIKDLPQRINDYETLLTRNRVWLSRNKDVCVITEEDVYQYGLTGAVARGSGVPYDVRKIDKYDAYGEVEFDIPVGEKGDSYDRYLVRMEEMRQSIRIIEQCIAKLRKMSKDDPYFFQTPDEKKLKVTIDGRGMKLPAGETYASSDNPRGELGFYIYNKKDGLKAHRMRIRSGAFYNLQVFTKAIIGRPIADAITLLSTIDPVVGETDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL22_PYRFU
Sequence: MAKRFGYSFQNFDPKRMARASARDLRISPKLAVEVCRELRGMMLNDALRYLDDVIALKRPVPLKRYNDSQGHKPGKGFGPGRYPVKVAKAIKKVLLNVKNNAVQKGLDPDKLKIIHIAAHKGPVLRGWYPRAFGRATPFNEQTTHIEVVVEEIRR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, Large ribosomal subunit protein uL22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GLYA_PSET1
Sequence: MLERSMNISDFDPELFDAIAKETARQEDHIELIASENYCSPRVLEAQGSQLTNKYAEGYPGKRYYGGCEHVDVVEQLAIDRANELFGSDYANVQPHAGSQANAAVFLALLNAGDTVLGMSLAHGGHLTHGSHVNFSGKLYNAIQYGLDETTGEIDYAQVEALALEHKPKMIIGGFSAYSGIVDWAKLREIADKIGAYFFVDMAHVAGLIAAGIYPSPVPHAHVVTTTTHKTLAGPRGGLIISACGDEAIYKKLNSAVFPGGQGGPLCHVIAAKAVAFKEALQPEFKVYQTQVVKNAQAMVAVMQERGYKIVSDKTENHLFLLDLINKDITGKDADAALGNAHITVNKNSVPNDPRSPFVTSGLRIGSPAITRRGFKEAESKELAGWICDVLDNINDESVQAQVREKVKAICAKLPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_BORBZ
Sequence: MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLKAKALFEILNNNQNVFGEDSGLCIEALNLEPGIYSKRYDTYKLCKKLSTNEKNQLILDLMKNEKNRKAYFICNISYISKNGQILNFEGIIKGKIALSLNDKKNYGFGYDSIFLTKNNKKLSDLTLEEKNKISHRGIAFLKFKKFLLKSLFNS
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: PF08_PLAF7
Sequence: MEELNKSGIYSKQFSLSQNKHNSERLQRLEKRLSGLHFSIELQKNEKIDKLNEKINSLEEKLIEMHENSNKTFEKLNEKLNDIRNDVTNYKNELEEFKNDHKKKLQLLEEKAEDFINKEKEDWSRLKIKLVKDFQHKAALLKEEMVEEYGLIEEKEDSLRKYYDCEINNIKSIIQNEISERIKTEKIILSDVDDKINEIMKIIRNEKTTRETYSENLVSLIEQYFSRIKKEIDMERLEREDTEETLVHLMEEALDKIGIPLA
What are the official names of this protein?
Uncharacterized protein.
Protein: YCH5_YEAST
Sequence: MYIIYGADHRISNCSLLKRRIPEARIFKLYPNDKTSRSSSASVAIPDYETQGQTAGQITPKSWLCMLSSTVPATKSSEWIFDTGCTSHMCHDRSIFSSFTRSSRKDFVRGVGGSIPIMGSGTVNIGTVQLHDVSYVPDLPVNLISV
What are the official names of this protein?
Putative transposon Ty5-1 protein YCL075W.
Protein: SYP_CHRVO
Sequence: MRASQFFISTLKEAPADADITSQKLMIRAGFIRKQAAGIYSWMPMGLRVVRKVETIIREEMNRAGGIEVSLPVVQPAELWQETGRWDAMGAELLRFKDRHERDFALQPTAEEVITDIARRELRSYRALPKNFYQIQTKFRDERRPRFGVMRGREFTMKDAYSFDRSAEDAGKSYDNMYAAYRRIFDRLGLTYRAVAADTGAIGGDRSHEFQVIADTGEDAIVYCPTSEYAANIELAEAVAPAGERPAASAALAKVHTPKVKTIAELVDFLKIDIKQTVKAVVVEGEQDEAVLMLVRGDHELNEVKAQKVAGIKNPLAFASPAAIRDAFGANPGSLGPVGFKGRVIADRTVAKMADFVIGANEDDQHYTGANFGRDCAEPEVFDIRNVVEGDPSPDGQGALAIQRGIEVGHVFYLGTKYSAAMNATFLDEDGKPKPFEMGCYGIGVTRILGAAIEQNYDDKGMIWPDSIAPFAVVVCPVGYDRSEAVKEAADKLYADLQARGVDVMLDDRGERPGAMFADWELIGAPHRVTIGDRGLKEGKVEYQHRRDSEATAVAADAILEHVLSKLA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPAL_ECO57
Sequence: MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRPTPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSFEHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMREMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIVNVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRIISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEGKHAVAP
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of both L- and D-alpha,beta-diaminopropionate (DAP) to form pyruvate and ammonia.  The D-isomer of serine is degraded to pyruvate, though very poorly; other amino acids (L-serine, D- and L-threonine, D- and L-beta-Cl-alanine) are not substrates.
What are the official names of this protein?
Diaminopropionate ammonia-lyase, DAPAL, 2,3-diaminopropionate ammonia-lyase, Alpha,beta-diaminopropionate ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the diaminopropionate ammonia-lyase family.
Protein: PSAB_PELHO
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSAISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLDVLPHPRGLGPLFTGQWNLYAQNPDSNSHFFGTSQGSGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFLFLVAGHMYRTNFGIGHSIKDLLEAHIPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWVSLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTNSPAFIAGRSIWLPGWLNAINENSNSLFLKIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: CK087_XENTR
Sequence: MSARISKQLRLSVPPCLANRTTASNSSSCVTEVEPLLQSFSSTLVLIVLATVIFCLVVLSLSTFHMHKSKMKKRKIEKAQEEYERDHCSPKAERGHLHGMGRGGTHGSPTSPTIQRKEHIRLDLGASVNEEPQLEASGLDRATEHLQQSVVLS
What are the official names of this protein?
Uncharacterized protein C11orf87 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SODC_NEUCR
Sequence: MVKAVAVVRGDSNVKGTVIFEQESESAPTTITYDISGNDPNAKRGFHIHTFGDNTNGCTSAGPHFNPHGTTHGDRTAEVRHVGDLGNIETDAQGNAKGTVTDNLVKLIGPESVIGRTVVVHAGTDDLGKGGNEESLKTGNAGPRPACGVIGISQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_ECOLI
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.  May also be involved in the metabolism of glycated proteins, but does not show sialoglycoprotease activity against glycophorin A.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC1_KLULA
Sequence: MNTGIRKDHLRKGETVSWYNSVIAGSVSGVFARMATAPMDTVKIRYQLQPVQEDKYKGIASTVRTIMKEEGLRALWKGNIPATAMYVVYGAVQFGSYSWFNNVWSAKFPRFSQQGQTLTVGALAGMTSSVVSYPLDLLRTRLIANRTSHRTSVAEECRQMWLNEGVRGFFTGISTAMTTVTLSTAIMFLTYETVNIVCENHEKEFWSRPVSASSGIIAGFVSKTMVFPIDTLRRRMQVMNSKRTVHFTKFPAVYHEYRYKSSTAIIYKILRQEGVSALYRGLTMGLCKSVPTTAISLFVYERTMDLFDHGQRWGRSP
What is the function of this protein?
Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
What are the official names of this protein?
Mitochondrial thiamine pyrophosphate carrier 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LIS1_DEBHA
Sequence: MLQPQILTARQQQELNKAIIQYIKPIAEEANDGDLIQKLSESLDVPLGSIDDSVIPNYLEKKWSTVLRLQHKIIDLEGEVSNLRTVIDSQQIVPSASASVIGKDKINWLPSSSIKAFKTQSHQLVQSVSIHPALPIILGGCSDGSLIIWNLVNDESLIPEKIIKAHIRGVNTIAWSKKPVDLSGKGSEAKGIAHVMATCSSDLSIKIWDGATFKHIRTLTGHEHTISSIVFSASKPNILYSVSRDKSVKVWDLVNGYCIKTFIGHSDWVRDIDVISVNSNLLQEQSDINPELGDFLVTCSNDQSIRLSHAESGTGLSLSIGHTHVIECVKFLPFHSNYIIDKYIKENESLFPNISPEVLDDPNYTNLLGYKYCISGGRDNSVKLWLLPPPVFRPHRHPLPSQLNNSQGWLIADLVGHQSWVKSLHIHPNGRFVFSGSDDKTIKIWDLSSLNVNGRVKCVKNLIGHEGFVNDIEFASFEITNNIHASKTADDGKTKTEEDRRNELMKSIESKIRCLFISGGVDNCIRLWS
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: IHFB_CAUVC
Sequence: MIKSELIARLANENPHLTQKDVERVVGVILERMIGALEDGGRVELRGFGALSVRSRPARTGRNPRTGEAVDVRAKHVPFFKSGKELRARLNADGDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: NORW_SALSV
Sequence: MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTWVADIDADAHVVKSQDKQWQYDKLVLATGATAFVPPITGRELMLTLNSQQEYRACETQLRDAQRVMIVGGGLIGSELAMDFCRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQRNIEVDAVIAATGLRPETALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPELPLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_WOLPP
Sequence: MTLKKLNLHLVSDSSGETVISVAKSALKHFRSVETIEYVWSFVKGEEQIDKILEEIERKSDEHNFVICTITDDGLRKYLKDNCIKLKIPYRAILSHIIREISSYLEIEKDEKLDLYTEINNEYFQRIEAINYTINHDDGQNIQDIDKADIILVGVSRTSKSPTSMYLAYRGYKVANVPFVSEIPFYVDLAKLRNKLTIGVTIDVRRLIEIRKNRLTSINNEGNNIYADPRKVEEEIKEAEEFFKQNNWPIIDVTQRSIEEVSATIIQYFNKI
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RS20_SALRD
Sequence: MPRHESAKKRMRQNEKRQKRNKSQKSRVRTKIKTLRSLDDKEEAEELLNDVKGDLDRLAAKGIIHENKAANRKSKLEKHVDALE
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ACPS_ECOL5
Sequence: MAILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWEIWKTHHQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVVNMHVTLADERHYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMN6_ECO24
Sequence: MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVIIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_PYRFU
Sequence: MLGEVSKILAKSSMAIAFTGAGISAESGIPTFRGKDGLWRKYRAEELATPEAFKRDPKLVWEFYKWRIKKILEAKPNPAHIALAELEKMGIIKAVITQNVDDLHREAGSKNVIELHGNIFRVKCTSCSYREYLKESDRIGWLLSQELPRCPKCGSLLRPDVVWFGEALPEKELTTAFSLAKKADVVLVVGTSGVVYPAAYIPYIVKESGGIVVEINIEPSAITPIADFFLRGKAGEVLPKLVEEIRRISK
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.  Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBHA_SERMA
Sequence: MNKTQLIDVIADKADLSKAQAKLALESTLAAITESLKEGDAVQLVGFGTFKVNHRSERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-alpha, HU-2, NS2.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PAND_SALRD
Sequence: MDLSMLRAKLHRLRVTEADLYYEGSITIDEELLDAAGLLPYEKVQVVNVNNGSRLETYTIPGEAGERTVCLNGPAARLAAPGDEVIVIAYAELTPSEAREHHPRVVHVDENNDVTKTRTLDVAKETDENLAPDGMEDVLIAEGPQS
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_BART1
Sequence: MAETIRIIGIDPGLRYTGWGVIDLAGNRLQFVAAGTVSSDVQCDLASRLCQIHKGLSEVVHQFMPHEAAVEHVFVNKDATATLKLGQARAIALLVPAQANCPVFEYAPNKVKKSVIGVGHGAKEQIHMMVKVLLPRAEFDSNDAADALALALCHSMHRKRIDQSYQARMAI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NOP10_KLULA
Sequence: MHLMYTLDAQGKRIYTLKKMTEDNEITKSAHPARFSPDDKYSRQRVTLKKRYNLLPN
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit NOP10, Nucleolar protein 10, Nucleolar protein family A member 3, snoRNP protein NOP10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ITR2_ASCSU
Sequence: EAEKCBZZPGWTKGGCETCGCAQKIVPCTRETKPNPQCPRKQCCIASAGFVRDAQGNCIKFEDCPK
What are the official names of this protein?
Trypsin inhibitor.
What are the subcellular locations of this protein?
Secreted.