PharMolix/UniProtQA huggingface dataset:
Protein: IDTB_CLAPA
Sequence: MDGFSILHEPPAAYKEVKWMADTFVAGMGLGWIVNYALMIRFSWKGRPHCMALLPLCNNIAWELTYTIVYPSANRVELLVFAIGLTLNFFIMVGARRSARVEWRHSPLLSEHAGFILLVGTLLCFTGHVALAMEIGPGLAYSWGAVVCQLALSIGGLFQLLQRNSTAGTSWTLWSSRFLGSCCTVAFAGLRCKYWPEVFGWLASPLVLWSLVTFLLADSAYGFCLYRVSHAETKARKKH
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of paspalitrems, indole-diterpene (IDT) mycotoxins that are potent tremorgens in mammals (PubMed:23468653, PubMed:29457197, PubMed:32077051).  The geranylgeranyl diphosphate (GGPP) synthase idtG is proposed to catalyze the first step in IDT biosynthesis via catalysis of a series of iterative condensations of isopentenyl diphosphate (IPP) with dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and farnesyl diphosphate (FPP), to form GGPP (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyltransferase idtC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation of the two terminal alkenes of the geranylgeranyl moiety by the FAD-dependent monooxygenase idtM, and cyclization by the terpene cyclase idtB then leads to the production of paspaline (Probable).  The cytochrome P450 monooxygenase idtP then catalyzes oxidative elimination of the pendant methyl group at C-12 of paspaline and generates the C-10 ketone to yield 13-desoxypaxilline (PubMed:32077051).  The cytochrome P450 monooxygenase idtQ may catalyze the C-13 oxidation of 13-desoxypaxilline to afford paxilline (Probable).  Considering that both paspalicine and paxilline were detected in C. paspali, idtQ also catalyzes the formation of paspalinine from 13-desoxypaxilline via paspalicine as an intermediate (Probable).  Finally, the alpha-prenyltransferase idtF prenylates paspalinine at the C-20 or the C-21 positions to yield paspalitrems A and C, respectively (PubMed:32077051).  The hydroxylation of paspalitrem A at C-32 by a still unknown oxidase affords paspalitrem B (Probable).
What are the official names of this protein?
Terpene cyclase idtB, Indole-diterpene biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVA_ACIC1
Sequence: MISFVSGRVAAVTPDSVIVEVGGFGVQLLATPATIARARVGERARFATSLVVREDSLTLYGFADDDERTVFELLQTASGVGPRLALAMLGVHSPTALRAAVATEDVKALALVPGIGRKTAQRIILELKDRLGTPSTAAAESTSGWRDAVHAGLLNLGYTARQADEAIAAIAGELDDSAAVDTATALRLALATLKRP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: DRC7_HUMAN
Sequence: MEVLREKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSEIQITVSAELPAFTKDTIDISKLPISYKTNTPKEEHLLQVADNFSRQYSHLCPDRVPLFLHPLNECEVPKFVSTTLRPTLMPYPELYNWDSCAQFVSDFLTMVPLPDPLKPPSHLYSSTTVLKYQKGNCFDFSTLLCSMLIGSGYDAYCVNGYGSLDLCHMDLTREVCPLTVKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEKAKPDALHGLRVHSWVLVLSGKREVPENFFIDPFTGHSYSTQDEHFLGIESLWNHKNYWINMQDCWNCCKDLIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDDVENLGKEDEDKSFDMPHSWVEQIEISPEAFETRCPNGKKVIQYKRAKLEKWAPYLNSNGLVSRLTTYEDLQCTNILEIKEWYQNREDMLELKHINKTTDLKTDYFKPGHPQALRVHSYKSMQPEMDRVIEFYETARVDGLMKREETPRTMTEYYQGRPDFLSYRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPAKPAEEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQRLNRHKELAPLKYLALEEKLYKDPRLGELQKIFA
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity).  Involved in the regulation of flagellar motility (By similarity).  Essential for male fertility, sperm head morphogenesis and sperm flagellum formation (By similarity).
What are the official names of this protein?
Dynein regulatory complex subunit 7, Coiled-coil domain-containing protein 135, Coiled-coil domain-containing protein lobo homolog.
What is the protein family that this protein belongs to?
Belongs to the DRC7 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Associated with the outer doublet microtubules (OD).
Protein: DCUP_EDWI9
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYNATRAQAGNFIALCKNAELACEVTLQPLRRFPLDAAILFSDILTVPDAMGLGLYFETGEGPRFTHSVTCHADIQRLPIPDPEQELGYVMDAVRTIRRSLRGDVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKVMFSDPAALHLLLDKLAQSVILYLNAQIRAGAQAVMIFDTWGGVLTGRDYREFSLRYMHQIVDGLQRESEGRRVPVTLFTKGGGQWLEAMADTGCDALGLDWTCDIADARRRVGGRVALQGNMDPSLLYAPPARIEQEVETILAGFGQGEGHICNLGHGIHPDVPPKHAGVFVDAVHRLSVPYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_AGRFC
Sequence: MTVIASELSAAIRSIPDYPKPGIIFRDITTLLGNPRAFRRAVDELVQPYAGTKIDKIAGMEARGFILGGAVAHQLSAGFVPIRKKGKLPHTTVRVAYSLEYGVDEMEMHVDAVQPGEKVILVDDLIATGGTAEGAVKLLRQMGAEIVSACFVIDLPDLGGRKKLEDLGVDVRTLVEFSGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_RHOPA
Sequence: MAEPIYRRVLVKLSGEYFAGPQDYGIDQATIDRVAGELIAARSLGIEIAVVIGGGNIFRGVEVSARGVSRTTGDTMGMLATVMNCLALAEALQRHGQKARTLAALMMPEVCELYTRAAAEQTLREGGIALLAAGTGNPYFTTDTAAVLRAAEIGAGAVLKATNVDGVYSADPKLDPNAKRFEKLTHSEALAGGYKVMDATAFALARETSLPIIVFSIAEPGSIGAVLSGAGRATVVAG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2_PHAAO
Sequence: MAIHLYKTSTSSTRNGAVDSQVKSNPRNNLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNEKEISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPISMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLISKNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGRRSRKRNKYSDSLILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRPD_GLOVI
Sequence: MMNEKHLQSLLICRLGGAALSEEAARELMEAWLAGEVPAALSGALLVAIAPLAITAGELAAMAKTLQEAAGAAPTGLPVLLDTCGTGGDGLGTFNISTAVAFVAAACGVPVAKHGARSASSRVGSADVLEHLGVHLSQERARVRAALDAVGITFLFAPGWHPALKAVAPVRRELGIRTVFNLLGPLVNPLVPTAQVLGVYHPSLVAPMAEALERLGRERFLVVHGGGGLDECSLTGPTALAGNLSGPICGSRLHPEELGLAAAPLEALAGGDVAENADILRRVLQGKGSRAQSEVVILNTAAALVAAGAAAGWMAGVTLARDCLADGAPWAKCEALIRFGNT
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL23_THEVB
Sequence: MTKVQPRALADLIKRPIITEKATVLLENNQYTFDVDRRATKPQIKAAIEELFNVKVTAVNTYHLPPKERRVGRFVGRRPRYKRAIVTLAPDSKIVLFPEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: COAA_LATSS
Sequence: MKNEMNYYEISREEWRYFHGRGEKYTAITDDELQQVSGLNDRISLTDVSDIYVPLRHLLQMKYEQFRENQIKQSEFLEIKPHKTPFIIGIAGSVAVGKSTTARLLQLLLSRVYPDKTVQMITTDGFLYSTSELKQKGILDKKGFPESYDMPQLISFLNAVKNNVAPVKAPKYSHQIYDIIPDEFDIIDDPDILIVEGINVLQLPTTEQIYVSDFFDFSVYVDANPSLIEKWFLERFDLLLDLAKDDPTNYYYPYAISDRASAFKMARRVWRDIDLRNLNDYILPTRNRADLILHKTKHHLIDKVFLRKY
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAG7_HUMAN
Sequence: MADLLGSILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQANKTYGCVPVANKRDTRSIEEAMNEIRAKKRLRQSGEELPPTS
What are the official names of this protein?
Sperm-associated antigen 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECB_PSEFS
Sequence: MTDQQNTEAAEAQGPQFSLQRIYVRDLSFEAPKSPAIFRQEWTPSVALDLNTRQKALEGDFHEVVLTLSVTVKNGEEVAFIAEVQQAGIFLIQGLDEASMSHTLGAFCPNILFPYARETLDSLVTRGSFPALMLAPVNFDALYAQELQRMQQEGSSTVQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALT_SALTY
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALVTSPAGYGKTTLVSQWAAGKNELGWYSLDEGDNQQERFASYLIAAIQQATGGHCSTSEAMAQKRQYASLTSLFAQLFIELAQWHRPLYLVIDDYHLITNPVIHDAMRFFLRHQPENFTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFNHQEAKQFFDRRLSSPIEAAESSRMCDDVAGWATALQLIALSARQNHTSAHHSARRLAGINASHLSDYLVDEVLDNVDVSTRHFLLKSAILRSMNDALIVRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFSYHPLFGSFLRQRCQWELAAELPEIHRAAAESWMEQGFPSEAIHHALAAGDAQMLRDILLNHAWGLFNHSELALLEESLKALPWESLLENPRLVLLQAWLMQSQHRYSEVNTLLARAEQEIKGVMDGTLHAEFNALRAQVAINDGNPEEAERLAKLALDELPLAWFYSRIVATSVHGEVLHCKGDLSQSLSLMQQTEQMARHHDVWHYALWSLIQQSEIQFAQGFLQAAWETQERAFQLIKEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIAVLSTFQPQQQLQCLTLLVQCSLARGDLDNARSQLNRLENLLGNGRYHCDWISNADKVRVIYWQLTGDKKSAANWLRHTPKPAFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNCNLLLLNQLYWQSGRKNDAQRVLLDALQLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPEMEQHRAQRILREINQHHRHKFAHFDEGFVERLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELAVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: KGUA_BAUCH
Sequence: MLYIISAPSGTGKSSLLQALLRTKRLPLHEIRISISHTTRAMRPGEINGQHYYFISVEEFEKLIDQDAFLEYARVFNHYYGTLRQEVDSILINSVDILLDIDWQGAKQIYAIRKDVRSIFIIPPSKDELHRRLHKRGQDQEEVINQRISQAVAEMIHYTEYDYLIINDDFHTALSDLNTIICAEQLHMNNQKIRYKTLISRLLQ
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_META3
Sequence: MGIVMVKLKVMPVSPEVNKDELSAKIKETVESMDIICRNIEVEPLAFGLYAVFPLIEMEEKEGGTEPVEEALANLDDVESVESVEVSLV
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: IF1_PARL1
Sequence: MSKEELLEFPGVVTELLPNATFRVKLENEHEIIAHTAGKMRKNRIRVLAGDKVLVEMTPYDLTKGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_SHEB5
Sequence: MKTFTATPETVTRDWFVVDADGKTLGRIATEIATRLRGKHKPEYTPHVDTGDYIIVVNAEKVTVTGNKAKGKTYYSHSGFPGGIKQISFEKLQAQKPEMIIEKAVKGMLPKGPLGRAMFRKLKVYAGAEHNHTAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: EZY2_CHLRE
Sequence: MQLSSSLRSARSAAASSGCALASRPVVACRRVTPSVTRPGPFTIATGPLLPASRSKAGGGIRVFSSALYEFGQQLKEDLEHDLSRARVDAITNKTRIAELEQQRRILMAVGGMADDEPELKAALMQLEEILGVSFNELQLMLAETLADHPAKMDNLAAMAAVVGTGSDGGGDESGDRRTADAADADGDGDGGERAWLRFKADVRACLADLRNRKGGITLHRAIVKDMVSASSNPGARRSSSSVDKMAREELDRLMPFLLDDFLDNMPGLKAAFTGKAEPGAEGDDGEDEEEGEAQGVGEDAVDSSSGGSGGGGVLSCTAWQQVLGRTVPASSPTLALVLARGYLAMAPRQYRALALVRMILPGKTGGGVDGALTRKEGLSLLKKLRPGISGLADKDKQWLEWVIARLAAEFAVQPAGDGHEPEPKRPELPPTAVQREPPAEEQHKPTAGARDSPNM
What are the official names of this protein?
Ezy-1 protein.
Protein: XYL1_ASPTN
Sequence: MATPTIKLNSGFDMPLVGFGLWKVNNDTCADQVYEAIKAGYRLFDGACDYGNEVEAGQGVARAIKEGIVKREELFIVSKLWNSFHDGDKVEPICRKQLADWGVDYFDLYIVHFPVALKYVDPAVRYPPGWSAKGDGSIEFSNASIQETWTAMETLVDKKLARSIGVSNFSAQLLMDLLRYARVRPATLQIEHHPYLTQPRLVEYAQKEGIAVTAYSSFGPLSFLELQVPNATNISPLFEHDVVKSVADKHGKTPAQVLLRWSTQRGIAVIPKSNNPTRLSQNLEVTGWDLEQSEIDAISALDIGLRFNDPIGYGMYVPIF
What is the function of this protein?
Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable NAD(P)H-dependent D-xylose reductase xyl1, XR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: HBB_MARFO
Sequence: VHLTGEEKAAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSPDAVMGNPKVKAHGKKVLNSFSEGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RECO_BRASO
Sequence: MEWTDDGIVLGLRRHGESSAVVELLTREHGRHLGLVRGAAGKRMRPVLQPGNTVRAIWRARLDEHLGMYAVDGLTLRAAELMSASHGAYGVTHLASLARLLPERDPHEDMYFRLEHALDDFADAGAAAAHIVRFELAILTELGFGLDLESCAATGETSDLIYVSPKSGGAVSRTAGAPWADRLLPLPPFLRESDEDHGWSDQDLLDGFRLTGLFLLRHVLEPRGQGHSDAREGFINAVTRARTRLTRA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: IF2_STRT1
Sequence: MSKKRLYEIAKEVGVESKVIVAKAQELGLSVKSHSSSVEEADANRITSSLKAGTAKDESKPAPKATPTPKEEKVEPKVDKASVAKSAPAKETSKAEVKEASVALKKPKSRNFKAEREARAKAEAERRKNGGGRDNRNRNQQGNDQGKRHNNDRRNQKGNGQGDHNKGNRDNSTNHDRNFQGKLRNDQNQNNRRDNARNNQAGPRIDLKARAAALKAEQNAEYSRQSETRFREEKAAEQRRAKEQEKARKEKQQAEVAVQKAAAETKPAPKPAPVAPQSAPTAQVQDTRRKKVRPNKSRDNRRVNEDGPKQTRNNKWNNQNQVRNQRNSNWNKNKNKKGKNNRGNSAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEATKKEEVDNADIERFFVDEDYLNKDAMVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEGGKKITFLDTPGHAAFTSMRARGASVTDITVLIVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPDANPERVIGELAEHGVISTAWGGDSEFVEISAKFGQNIEELLETILLVAEVEELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRIKTAGPSAPVSITGLNEAPMAGDHFAVYEDEKAARAAGEERAKRALMKQRQQTHRVSLDNLFDTLKAGEMKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINESDITLAEASDAVVIGFNVRPTPQARQQAETDEVEIRLHSIIYKVIEEIEDAMKGMLDPEFEEKIIGEAVIRETFKVSKVGTIGGFMVTNGKITRDSSARVIRDGVVIFDGKLASLKHYKDDVKEVGNAQEGGLTIENYNDIKVDDVIEAYIMEEIKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAA3_BOVIN
Sequence: MGKPARKGCDWKRFLRNNWLLLSTVVAVVLGIVIGVLVREYSKLSNLEKFYFSFPGEILMRMLKLVILPLIVSSMITGVATLDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVNEIDRTGNTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTTREEVELSEEPGTNSTEATVTAIMTTAISKNKTKEYKVVGMYSDGINVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMKIVQIIMCYMPIGILFLIAGKIIEVEDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFAMGMAQALLTALMISSSSATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQPGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFTLESTALDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
What is the function of this protein?
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate.  Can also transport L-cysteine (By similarity).  Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion.  Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (By similarity).  Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli.  Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).  Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport.  Negatively regulated by ARL6IP5 (By similarity).
What are the official names of this protein?
Excitatory amino acid transporter 3, Excitatory amino-acid carrier 1, Renal high affinity glutamate transporter EAAC1, Sodium-dependent glutamate/aspartate transporter 3, Solute carrier family 1 member 1.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Synapse, synaptosome. Early endosome membrane. Late endosome membrane. Recycling endosome membrane.
Protein: DTX21_ARATH
Sequence: MAGGGGELTAALLKKTAENGGEEKDELGLKQKVWIESKKLWIVAAPAIFTRFSTFGVSIISQSFIGHLGPIELAAYSITFTVLLRFSNGILLGMASALETLCGQAYGAKQNHMLGIYLQRSWIVLTGCTICLTPVYIFSGPILLALGQEERIVRVARIIALWVIGINFSFVPSFTCQMFLQAQSKNKIIAYVAAVSLGVHVFLSWLLMVHFNFGITGAMTSTLVAFWLPNIAQLLFVTCGGCKDTWRGFSMMAFKDLWPVFKLSMSSGGMLCLELWYNSILVLLTGNLKNAEVALDALAICLNINGLEMMIALGFLAAASVRVSNELGSGNPKGAKFATLTAVFTSLSLGIVLFFVFLFLRGRVSYIFTTSEAVAAEVADLSPLLAFSILMNSVQPVLSGVAVGAGWQGYVTYVNLACYYLVGIPIGIILGYVVGLQVKGVWIGMLFGIFVQTCVLTVMTLRTDWDQQVSTSLRRLNRWVVPESRDVNQVSSEE
What are the official names of this protein?
Protein DETOXIFICATION 21, AtDTX21, Multidrug and toxic compound extrusion protein 21, MATE protein 21.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CU125_LOCMI
Sequence: GYLGGYAAPAYAGYAAPAYAGYAAPAYAAPVAAVAHAAPAVAVAHAPVPSSAANTYRISQTARLAYAAPAVAHAPLAYAAPAVAHAPLGYAAPAYGVARYAAAAPALGYGYGAYGYAAPALGYGHALVH
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 12.5, LM-ACP 12.5, LM-12.5.
Protein: RS15_PIG
Sequence: MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S15, RIG protein.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PSD_ANASK
Sequence: MNDRLFISALRLLPKNALSRAVGALTRWRAPVPVRLAAMRAFARRYGIDLSECPDLDVYRTFGEFFARPLRPGLRPIAPGERVVASPVDGAVSETGRVEAGRLVQAKGIDYPAAALLGDEALAARFAGGAYATLYLAPKDYHRIHFPLGGKVTGWRYVPGKLWPVNPASVRTVRGLFALNERLVTVLETPLGACAVVAVGATVVGRVCAYYDPSIPFTNLPGAAPRRHDYETPIPVEKGQELGAFEMGSTVILLFEPGKARLDPRLAPGVRVRVGEPLGGAA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.