PharMolix/UniProtQA huggingface dataset:
Protein: SEPF_STRP8
Sequence: MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRASSHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMSTSGIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQARRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: O162_CONCL
Sequence: MKLTCVLIVAVLVLTACQFTAAIDSRGGQENPAPRSTGLMRRKSQTERNCIPKNHFCGLLHHSRNCCTPTCLIVCF
What are the official names of this protein?
Conotoxin Cl6.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDD_STAA8
Sequence: MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ITR2_BRYDI
Sequence: RGCPRILMRCKRDSDCLAGCVCQKNGYCG
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Trypsin inhibitor 2, BDTI-II, Trypsin inhibitor II.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRTW_PARS1
Sequence: MSGRKPGTTGDTIVNLGLTAAILLCWLVLHAFTLWLLDAAAHPLLAVLCLAGLTWLSVGLFIIAHDAMHGSVVPGRPRANAAIGQLALWLYAGFSWPKLIAKHMTHHRHAGTDNDPDFGHGGPVRWYGSFVSTYFGWREGLLLPVIVTTYALILGDRWMYVIFWPVPAVLASIQIFVFGTWLPHRPGHDDFPDRHNARSTGIGDPLSLLTCFHFGGYHHEHHLHPHVPWWRLPRTRKTGGRA
What is the function of this protein?
Converts beta-carotene to canthaxanthin via echinenone.
What are the official names of this protein?
Beta-carotene ketolase, Beta-carotene oxygenase.
Protein: RS9_SHIFL
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPMELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: P2C59_ARATH
Sequence: MGYLNSVLSSSSQVHSDDGPVSGGGLSQNGKFSYGYASSPGKRSSMEDFYETRIDGVEGEIVGLFGVFDGHGGARAAEYVKQNLFSNLIRHPKFISDTTAAIADAYNQTDSEFLKSENSQNRDAGSTASTAILVGDRLLVANVGDSRAVICRGGNAIAVSRDHKPDQSDERQRIEDAGGFVMWAGTWRVGGVLAVSRAFGDRLLKQYVVADPEIQEEKVDSSLEFLILASDGLWDVVSNEEAVGMIKAIEDPEEGAKRLMMEAYQRGSADNITCVVVRFFSDQAGGIGSSSTNIPIDHGIVPDRISGDSST
What is the function of this protein?
Protein phosphatase that modulates defense response to pathogenic bacteria, conferring resistance and promoting salicylic acid (SA) accumulation.
What are the official names of this protein?
Probable protein phosphatase 2C 59, AtPP2C59, HopW1-1-interacting protein 2, Protein phosphatase 2C WIN2, PP2C WIN2.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: BUD32_CRYNJ
Sequence: MAASTPLLSRGTLIKQGAEAKVYALPSLFPEPTTYHPGSSSSFSAASPTPVILKHRFTKTYRHPTLDASLTSQRLTFEARALARAAKAGVTVPKVVWVDEKAGVIGMERIEGWSVREILGGGAEGEVEVIEEQEIEEDVENKAEDSAVREEPEGPESEGLKALKNLGVTQEHLMRSIGAALARLHKTMIIHGDLTTSNMMVRLTPGGSGPYEIVLIDFGLSSQAQFPENYAVDLYVLERAFASTHPRSEKLYAGVLETYAEGLGEKKWKPIQIKLKDVRRRGRKRDMTG
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
EKC/KEOPS complex subunit BUD32, Atypical serine/threonine protein kinase BUD32.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. BUD32 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere.
Protein: RL15_METFK
Sequence: MKLNTIKPAEGAKHARRRVGRGIGSGLGKTGGRGHKGQKSRAGGFHKVGFEGGQMPLQRRLPKRGFNSLTKADTANVRTADLVRVEADVIDILALKQANVIPSGARAVKVYLSGDVTRAVTVQGLALSKGARAAVEAAGGKIVE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ILVD_STAAS
Sequence: MRSDMIKKGDHQAPARSLLHATGALKSPTDMNKPFVAICNSYIDIVPGHVHLRELADIAKEAIREAGAIPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADAAETVINAHWFDGVFYIPNCDKITPGMILAAMRTNVPAIFCSGGPMKAGLSAHGKALTLSSMFEAVGAFKEGSISKEEFLDMEQNACPTCGSCAGMFTANSMNCLMEVLGLALPYNGTALAVSDQRREMIRQAAFKLVENIKNDLKPRDIVTREAIDDAFALDMAMGGSTNTVLHTLAIANEAGIDYDLERINAIAKRTPYLSKIAPSSSYSMHDVHEAGGVPAIINELMKKDGTLHPDRITVTGKTLRENNEGKEIKNFDVIHPLDAPYDAQGGLSILFGNIAPKGAVIKVGGVDPSIKTFTGKAICFNSHDEAVEAIDNRTVRAGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAASGGPIALIEDGDEITIDLTNRTLNVNQPEDVLARRRESLTPFKAKVKTGYLARYTALVTSANTGGVMQVPENLI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: BM03_DROME
Sequence: MKFLSLAFVLGLLALANATPLNPGNVIINGDCRVCNVRA
What is the function of this protein?
Secreted immune-induced peptide induced by Toll signaling (PubMed:29920489).  Has a role in resistance bacterial and fungal infections (PubMed:25915418, PubMed:29920489).  The strength of antimicrobial activity appears to correlate with the overall level of expression (PubMed:29920489).  Has no activity against the fungus C. glabrata in vitro (PubMed:29920489).
What are the official names of this protein?
Bomanin Short 3, Bomanin-3, Immune-induced peptide 3, DIM-3, DIM3.
What is the protein family that this protein belongs to?
Belongs to the bomanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TM168_BOVIN
Sequence: MCKSLRYCFSHCLYLAMTRLEEVNREVNMHSSVRYLGYLARINLLVAICLGLYVRWEKTANSLILVIFILGLFVLGIASILYYYFSMETASLSLSNLWFGFLLGFLCFLDNSSFKNDVKEESTKYLLLTSIVLRILCSLVERMSGYVRHRPTLLTTVEFLELVGFAIASTTMLVEKSLSVILLVVALAMLIIDLRMKSFLALPNLVIFAVLLFFSSLETPKNPVAFACFFICLITDPFLDIYFSGLSVTERWKPFLYRGRICRRLSVVFTGMIELTFFILSAFKLRDTHLWYFVIPGFSIFGIFWMICHIIFLLTLWGFHTKLNDCHKVCFTHRVDNNSLDRIMASKGMRHFCLISEQLVFFSLLATAILGAVSWQPTNGIFLSMFLIVLPLESMAHGLFHELGSCLGGTSVGYAIVIPTNFCSPDGQPTLLPPEHVQELNLRSTGMLNAIQRFFAYHMIETYGCDYSTSGLSFDTLHSKLKAFLELRTVDGPRHDTYVLYYSGHTHGTGEWALAGGDILRLDTLLEWWREKNGSFCSRLIIILDSENSTPWVKEVRKINDQYIAVQGAEMTKTIDIEEADPPQLGDFTKDWVEYNCNTTNNICWTEKGRTVKAIYGVSKRWSDYTLHLPTGSDVAKHWMLYFPRITYPLVHLANWLCGLNLFWICKTCFRCLKRLKMSWFLPAVLDTGQGFKLVKS
What is the function of this protein?
Plays a key role in maintaining the cardiac electrical stability by modulating cell surface expression of SCN5A.  May play a role i the modulation of anxiety behavior.
What are the official names of this protein?
Transmembrane protein 168.
What is the protein family that this protein belongs to?
Belongs to the TMEM168 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOY_STAA3
Sequence: MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFNIEFITKLEGAHLDYEKENSEHFNVEIAK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: RLMD_SHEB9
Sequence: MAQFFKAKPNSSKQLSAKLSLSVNQLDHLGAGIAQHQGKVVFIPGALPDETVTVQLTEQKKNYARAKLIKVDTPSSERVEPECPHYHTCGGCDLQHMSLSGQREHKEAALLDIMAKFAGAEGGALSPALTGEGWHYRRRARLATLFDKNTKHLSLGFRAASSSNVVPISQCQVLAKPLSDLIVPFAKLLNQLSAKASLGHLELIAADNGHFAVLRITKALNDKDLAKLSAFAEQHQIHICLQDNEGQFQGVGAELVLPVYQLLDDKAESDAVSLSFTPGNFVQVNGQINKAMVAQAMDWLAPAPDERILDLFCGMGNFSLPLAKMGADVIGVEGVAEMVTQARVNAKANNLDKLTFYHGDLSADLSLEPWMGKIDKLLLDPARAGAFESLQWLKKMKPRKVVYVSCNPASLARDSAVLLERGYRLQQLGLIDMFPQTHHIEAMALFELTK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: RUVB1_CANAL
Sequence: MVQITEVKENQSSRESRTAAHTHIKGLGLNEQGIAKPIEGGFVGQNEAREACGIIVDLIKSKKMSGKAVLIAGPPATGKTALALAISQELGPKVPFCPIVGSELYSAEVKKTSALMENFRRAIGLRIKETKEVYEGEVIELTPEEAENPLGGYGKTISHVIVGLKSAKGTKTLRLDPVIYESIQKERVTIGDVIYIEANTGAVKRVGRSDAYATEFDLEAEEYVPLPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDVLSMMGQLLKPKKTEITDKLRTEVNKVVSKYIEQGVAELVPGVLFIDEVNMLDMEIFTYLNRALESSIAPIVVLASNRGLTTVRGSDDGVKAPHGCPPDLIDRLLIVRTLPYNQEEIKTIIGKRASLEGLTLTDDALEKLSKQGLTTSLRYAVQLLTPAGVLSTTAGRSEITVQDIEECEFLFLDSRRSTKVLQETKTFL
What is the function of this protein?
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.  The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair.  Also involved in pre-rRNA processing (By similarity).
What are the official names of this protein?
RuvB-like helicase 1.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_PSYIN
Sequence: MSDYKSTLNLPKTGFPMRANLANREPNMLKNWYSNDLYGKIRAAKKGKKTFILHDGPPYANGDIHIGHSVNKILKDIIIKSKTLSDFDAPYIPGWDCHGLPIELKVEQKVGKPGKKISAAEFRKKCREYAARQVDGQRKDFKRLGVLGEWDKPYLTMDFGTEANIVRALAQVIKNDHLHKGSKPVHWCTECGSALAEAEVEYEDKLSPAIDVAFSAVDNEQVLNCFSAVTDNLGEGNVSAVIWTTTPWTLPANRAIALAQKVEYSLVQAGERRLIIATDLVADCLKRYGNEDFSTLAICKGIDLEKQLFNHPFLDLQVPAILADYVTVDAGTGCVHTAPGHGQDDYAVGLRYDLEVANYVADNGVFRDDTEFFAGLHVFKANDRVLEVLAERNALLCSIKLNHSYPHCWRHKTPIIFRATPQWFIAMDQKSLRADALAEIQAVKWIPSWGQQRIEKMVENRPDWCISRQRTWGVPITLFVHKETDELHPNSVEMMELIARKIEIDGIQAWWDLEPETLLGFEAEEYRKVTDTLDVWFDSGTTHASVVAKREEYTLESGEQAAADMYLEGSDQHRGWFQSSLMTSMAINNKAPYKEVLTHGFVVDGNGKKMSKSLGNVMSPQTVMNNLGADILRLWVASTDYTGEMTVSDEILNRSADSYRRIRNTSRFLLANLNGFDPTTDLVPNEEMVALDRWIVAQTLILQNDVIEAYESYSLHAVYQKLTHFCSIELGSFYLDIIKDRQYTAKADSNAHRSCQTALFHIAEALVRLMAPILSFTADEIWARLPGARDEFVFTTVWYDGLFSLSDNEALSSAAWSKLTLVRAEVNKALEIARKENAIGGGLEAEVILYASDEIATLLTTLEDELRFVLITSQAQVKPLADAPQLALKTEVTGLLVSVVKSAAPKCERCWHHREEVGQNKQHPELCGRCVTNIEGQGEIRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_DICNV
Sequence: MNTKISEHTPAMQQYLTIKEDFPDLLLFYRMGDFYELFFDDAKKAGALLNITVTARGKIRGKPIPMAGVPAHALENYLAKLVKQGMSAVICEQVGEVGKGLVERAVTRIITPGTLTDENLLDEARDSILLSLFCFQNNYFFAYADITRGDFQLTMGLNEQELQSEIERLRPAEILMPETANVPAFITALKPHRQPDWYFDSDSSYRLICEYYQTTTIDGFGIAPDDPALSAAGCLLQYLHDTHKYHLPPLKPLQKQHDHQYLLLDATTRRNLELEYTLNGESKHSLIATINRCSTAAGVRTLKRWINQPLIQHEYILERQEAVTALLTHADLDEIAKTLRATADIERITTRIALQTAKPRELAQLRDTLMQLPAINALLQTSAAHSPLLAAATQALMHCPQLGDLLMKALVEAPPLTLKEGGIFAAGYLPELDALHELTDHSAQLLEKMEQEEKAQTGLNTLKIGFNRVHGYYIDIPRSQAANAPAHWIRRQTLKNSERYVTESLKTLEERLLNAQDEALALEKQAYTELLITLDKQRDDLYRLATALAESDVLTCFARLAKEHHYCRPQFSNQIEIQITAGRHPVVEQLSAQPFIANDLVLHQKRQLLILTGPNMGGKSTYMRQTALIVILALAGSYVPAKEARIGRINRIFTRIGASDDLAGGRSTFMVEMTETANILNNADEHSLVIMDEIGRGTSTFDGLSLAWAVADHLLQKNRALTLFATHYFELTALVERHQHGANIHLSAAEDQEHIVFLYHIEEGATSKSYGLHVAKLAGVPQAVIHNANAKLRQLEEKRVPQRAHQALLPIESQKPSLSPQIKNILQQIQEINPDELSPKAAHEWLYQLKTLVRDLDKNEL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FKBP6_DROME
Sequence: MEENFEPYTPQLLKNPLSYSDLVKKGVEFEVDNSQQNHARDLGLDSDSDSDYEDALDVDGEELRSPWTYSFDELRALMSEIDENIYKRITRTGHVDREAVPNKARVSVRYSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFGELGCPPRIKPKADALFKVEVIDYSLIGDAKGIDAIPQEDRDKFCVVYPKAVDLHLHGKDSVKLGRYQSAATAFERAVSSLNYCRMANDEEERKQTELLTTLNQNLMIVYNKMNKPKRACIMMKALRHLTMGNPSCKALFQEGRALAALGEYNLARNAYLQAQAKQPANKEISDEIISMNKRISKYEEASRDIWARAFSLKNSKSDVRKTPAQLEKEAKEQDFNDKMEDLIRRFKNTSDQQVSFSRKSYSNAQFDATCKLAKEHNLKLTLSPIQEDVLTLSKPDVKFA
What is the function of this protein?
Co-chaperone required during oogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Acts as a co-chaperone via its interaction with Hsp83/HSP90 and is required for the biogenesis of all three piRNA major populations.
What are the official names of this protein?
Inactive peptidyl-prolyl cis-trans isomerase shutdown.
What is the protein family that this protein belongs to?
Belongs to the FKBP6 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Present in the cytoplasm of germ cells. Component of the meiotic nuage, also named P granule, a germ- cell-specific organelle required to repress transposon activity during meiosis. Also present in Yb bodies.
Protein: TDXH2_SULTO
Sequence: MSEEKIPLIGEKFPEMEVITTHGKIKLPDYYQGKWFVLFSHPGDFTPVCTTEFYSFAKKYEEFKKLNTELIGLSVDSNISHIEWVMWIEKNLKVEIPFPIIADPMGNVAKRLGMIHAESSTSTVRAVFIVDDKGIVRLIMYYPMEIGRNIDEILRSIRALQLVDKSGVVIPANWPNNELIGNKVINPPPRTVKDAKLRINQPFDWWFTYKEI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin 2, Thioredoxin-dependent peroxiredoxin 2.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_DICNV
Sequence: MTDSAFTRAARVIPGGVNSPVRAFKSVGGEPIFIARAEGAYLYDVNGRRYIDYVGSYGPMINGHAHPEIVAAVCRASRNGMSYGAPNELETELAEKIVARVPSVEMVRMCNSGTEATMSAIRLARAATNRTQILKFAGCYHGHSDALLVSAGSGALTFGSPNSPGVPEDFVRHTLTAPYNDIAALERIFVQHGKNLAAVIVEPIAGNMNCVPPLPEFLPTLRALTKKYGVILIIDEVMTGFRVAYAGAQGLYDIAADLTTFGKVIGGGMPVGAFAGSADLMSMLSPVGSVYQAGTLSGNPVAMIAGITNLRLTEAEGFYDTLAAKTQKLAEGLRQAAKKNGIHVVVNDVCGMLGLFFTDLPQVCNFADVQTADTARFAKFFHAMLAEGVNLAPSAYETIFVSMAHDDAVLDETIAIAEYVFAHLEE
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG40_ALHV1
Sequence: MGQPGQQSSHEQSNMLAAVCSISFVNLWHSKAKTYAVWCVRVVKQEEPVENTGDSQLGSPRNSNLYLVSYELLLSEKNMLPDEQLNFTSTGGDILNFMRWEMALRAKHPVISLLSRHCGNMEAVFSLQLNGIMIKGATLQTVARPPLRQACFAYMWCHAKASADEGGQHLVLDSLEATIKTKLGTYTYSNNTGEADPPSTKVARRQDQVKILDIFEPCDYVLNLGGSDVTVKLIDVPFDCLVVNDECRWNLGLNVFFSALYKKIYGGIYGFKPLFFIAEPSDLTFPTSPFFSSFPNISIEYSPNFKDFSKTMSQSSLAAILTTGDCYKVNNFLLECITGISVPPIPEALRHGTGISWPLGATELNNKLIMGDLPYVHIKHPHVLYIINFKFNTRFCCGSLSGDEIPKLLARYSTGHLKQNLNSWYSYLVFSVMNFCNLHNLQWIAFNHSMFYLASHAQDQVSTPPVAAVPFKTTNTCI
What are the official names of this protein?
Uncharacterized gene 40 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BBLF2 family.
Protein: SPLF_STAAW
Sequence: MNKNIIIKSIAALTILTSITGVGTTVVDGIQQTAKAENTVKQITNTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVSSDAIIQPGSSGSPILNSKHEAIGVIYAGNKPSGESTRGFAVYFSPEIKKFIADNLDK
What are the official names of this protein?
Serine protease SplF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: IDNT_ECOLI
Sequence: MPLIIIAAGVALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH
What is the function of this protein?
Transports L-idonate, D-gluconate and 5-keto-D-gluconate, from the periplasm across the inner membrane.
What are the official names of this protein?
Gnt-II system L-idonate transporter, L-Ido transporter, 5-keto-D-gluconate transporter.
What is the protein family that this protein belongs to?
Belongs to the GntP permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAA_ALKOO
Sequence: MQDNLPQIWEKTLNLIKPELTEVSFTTWIKSIEVISLEGNTMILGVPNVFTKDILTARYATLISNALKQTTSKNFEIRFIVPSEEKISKTEESQKKLEGSVNISVASDQFVSNNLNPKYTFDTFVIGNSNRFAHAASLAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHFILQNNPKAKVVYVSSETFTNELINSIRHDRNVEFRNRFRTIDVLLVDDIQFIAGKESTQEEFFHTFNALHESNKQIIISSDRPPKEIPTLEDRLRSRFEWGLITDIQPPDLETRIAILYKKAQMENIDVPNEVLTHIAKKIQSNIRELEGALIRIVAYSSLTNSEITVELASEALKELFSSKARQLNIDLIKEVVANKYNMKIEDFNSKKRTRSISYPRQIAMYLSRELTDLSLPKIGEEFGGRDHTTVMHAHEKISKDILADDNIKEKIERIAKEIKGD
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_BRUMB
Sequence: MIGKLKGVIDEIAEDHAVIDVHGVGYVAFCSARTLGNLGGAGEAAILFIETYVREDMIRLYGFATQLEREWFRLLQNVQGVGAKVALAVLGTLSPSELANAIALRDIAMVSRAPGVGKKVAERIVTELKNKAPAFAGEASGTIGLKQELGAGAAPAPVADAVSALSNLGYSRDQAANAVAAALKETGEGADSAKLIRLGLKELSQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SSRP_ENT38
Sequence: MTKKKVHKPGSATIALNKRARHEYFIEEEFEAGLSLQGWEVKSLRAGKANISDSYVILIDGEAFLFGANFTPLAVASSHYVCDPIRTRKLLLNQRELESLFGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKDREWQVDKARIMKHAGR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HIS7_COREF
Sequence: MTTAPRIGRATRTTSESDITVEINLDGTGTVDIDTGLPFFDHMLTAFGVHGSFDLTVHAKGDIEIDAHHTVEDTAIVLGQALLDAIGDKKGIRRFASCQLPMDEALVEAVVDISGRPYFVINGEPDHMISAVIGGHYATVINEHFFETLALNSRITLHVICHYGRDPHHITEAEYKAVARALRAAVEMDPRQTGIPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_ECOL5
Sequence: MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWRKICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.