PharMolix/UniProtQA huggingface dataset:
Protein: SYI_LACAC
Sequence: MRIKDTLNLGKTKFKMRGNLPVREAEWEKEWEDNHLYEQRLKLNEGHPRFDLHDGPPFANGNIHMGHALNKISKDIIVRYKNMNGYYAPYVPGWDTHGLPVEQQLAKKGIDRKTMDRAKYRELCRQYAEEQVQKQMTDFKRLGVMADWDNPYITLQHEFEGQEIRVFGEMYKKGYIYKGKKPVYWSWSSESTLAEAEVEYKDVEANSIFVAFPVVDSKGIIDPKDTYFVIWTTTPWTIPANEAICVNPKFDYSVVQVGDKKYVVATGLLDKVAEEIGWDDYKVVQTVKGADMEYMKAKHPLYDKESLVTEGFHVTLDDGTGLVHTAPGFGADDFNVGQKYDLPVFSPVDAHGRYTDEVPELEGMFYQDVDKLMVEKLKDAGALLKLKVFTHSYPHDWRTKKPVIFRATTQWFASIAPFRDQILEQIDNAKFIPSWGKTRLYNMIKDRGDWVISRQRAWGVPLPIFYAEDGTPIVTPETIEHIAEIFDKEGSNAWYTHTAKELLPEGFTSEHSPNGEFTKEKDILDVWFDSGSSWSGVMEKRDGLHYPADLYLEGSDQYRGWFNSSLITSVAVTGKAPYKEVLSQGFVLDDKGHKMSKSLGNVISPNDVIKRMGAEIIRLWVAQADTTSDVAVSMGILQQSAESYRKIRNTFRYMLANTSDFDPKENGVAYDDLRSVDQYMEIKLNDLVAECLAAYDKFDFTTVFKKIFNFISNDLSAFYLDFAKDVLYIEGKNSLERRSMQTVIYDAAVKLTKILTPILPHTMEEIWGFLKEPEDYVQLANMPKVENYTNHDELLENWGKFMNLRDDVLKALEDARNKKLIGKSFEAAVTIYPDKETKAMLDDLDADFRQILIVSKLTIVDGEAPENAEKLNNASIVVEHAEGEVCPRCRMIRTDIGEDPKLPELCERCAKIVEEDFPEAAQEGLEE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_CLOBB
Sequence: MRKTALLNSDLSSVISKMGHTDMIAIGDCGLPIPAESERIDLALIKGIPTFMQTLKTTLLELQIEEVILAKETEAVSPDLYEEIKEVIGDVKITFITHEELKTTLKSCKAVVRTGEQTPYANIILKSGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_STAAC
Sequence: MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: ADDB_CLOBA
Sequence: MSIRFIYGRAGSGKSLFCINQIKKLIDSDKEKKIILLVPEQYTFTTENKVLNYIGERAFLNTHVLSFRTMCQKVFEECGGRVKQIIKDTGKHMLINKVLNEKIDDLSYFKKMSREQGFNNIISELITEFKKYNINIDALRDLTDKIDDNELVEKIRELSLIYEEFNVKMHSSYIDTDDELTLLAKKLLANNIYANSEIWIDEFTTFTPQQLEIIRILSKASVVNITLCMDKIENSDVEDITNVFSSIENTENRLLKLMEENNIGYLNPINLNSKLPYRFKNSEELSHIEKYCITYPFKSYKGKNKDVRLYKANNTYDEIEKVAKDIIRLVRDRNYRFRDISVVCRNIENYNKIISVIFNDYEIPFFMDQKIKLLNNPLIVLITSAFEVVLKNWSYESVFKYLKSGLTGFNIYDIDRLENFVLEHGIKSYKWNEEEIEKLKNIKIENGATEDELTIFNLMEEVRNSLISFHKLIEGKHYVRDICKALYEFLLSIKAFERIDEWIIKFEELKLEDKVKEYKQVESIVIDMLDQAVEVMGSDVVDTFEFFKILNSGFENEEIGVIPVALDQVNVGDIARIKGREVKALYIVGINDGILPAAHKDEGILSDRDRIELKEFGIVLAADGRSKAFEEQFVVYTALTIASEYLMLSYPMADFEGKSLRPSIIISRIKKILPNLVEESSLYDLSKRSDHFNKVISPIPTFNELIFALRRELEDEDIDEEYWGEVYNWFKENEDFKWKIENTFKGLRYSNTGEKVSRNKLLSLYKNDLGKLSFSVSRLEKYAECPFSYFIQYGLKAKNRKVYEFTPPDLGSFVHDILDSFTNKVKKEKIAWSDLDMIKCKNIVSELIDTKLKEDSGSILNSTNKYKYFSKRFKRVISKSVSVISEQMRRGEFEVFNNEFSFGSYNDGEAIVLELPSNEKVYLNGRIDRIDTLDLEGSTYLRIVDYKTGNKHFDLNQFYYGLQMQLLVYLDALIKNSEYILKKQALPGAVLYFKVDDPIIKTKGDITTEELEKEVLSNLKMNGLILKDAKVVKAMDRGIETDGYSLVIPAALKKDGDFKAGSEVVTEEQFTLLREYVNKKMIDLCEDMLCGDIKIQPTKDSDGSHCEFCDFSSICQFDSSIEDNKYKIIMKKSKDEIWNNIRDELNDDKKEN
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: RL18_STRPZ
Sequence: MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ENO_LACLM
Sequence: MSIITDIYAREVLDSRGNPTLEVEVYTEDGAFGRGMVPSGASTGEHEAVELRDGDKSRYNGLGTQKAVDNVNNIIAEAIIGYEVTDQQAIDRAMIALDGTENKGKLGANAILGVSIAAARAAADELGVPLYNYLGGFNAKVLPTPMMNIINGGSHSDAPIAFQEFMIVPVGAPTFKEALRWGAEIFHALKKILKARGLETAVGDEGGFAPKFDGTEDGVETILKAIEAAGYKAGEDGVMIGFDCASSEFYENGVYDYTKFEGEGGKKLSASEQVDYLEELVSKYPIITIEDGMDENDWDGWKILTERLGKKVQLVGDDFFVTNTKYLERGIRENASNAILIKVNQIGTLTETFEAIEMAKEAGFTAIVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRMAKYNQLLRIEDQLAEVAQYKGLKAFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y1121_CITRI
Sequence: MNKVYNTVWNESTGMWVVTSELTRKGGRRPRQIRRTALAGLIAGLLLPSAPALAVDYNNETLGSGATSSSMSLNAGDTATDTTINSGGSQRVSSGGSATSTTINSGGFQYVSSGGSATDTTINSGGYQHVSSGGSATDTTINSGGYLSVSGGGTAVDITQNSGGVIDTNTYATLSGTNINGSFSIVNGSASNMLLENGGFLSVLNGHQATNTTINSGGYLSVYGDGSAVDITQNSGGAISTDTSATLSGTNINGSFSIAGGSASNMLLENRGQLNVNSGHQATNTIINSGGNQHISGGGSATDTTINSAGFQYVYSGGSATSTTINRGGNQYVSGGSATNTTINSGGYLSVYGGGTAVDITQNSGGAIDTNTYATLSGTNINGSFSIAGGSASNMLLENGGYLNVNSGHQATNTTINSGGGLRVSGGGTAVDITQNSGGAISADTSATLSGTNINGSFSIANGSASNMLLENGGSLYVNSGHQATNTTINSGGGLRVSGGGTAVDITQNSGGAIDTNTYATLSGTNINGSFSIANGSASNMLLENGGYLYVDGGHQATNTTINSGGILSVSGGGTAVDITQNSGGVIDTNTYATLSGTNINGSFSIANGSASNMLLENGGFLYVNSGHQAMNTTINNSRSTMNVLGGGSATSTTINSGGYQYVSSGGSATSTTINSGGNQYVSSGGSATDTTINSGGSLVVFDGTAVDITQNSGGAITADTSATLSGTNINGSFSIANGSASNMLLERGSLYVEGGHQATNTTINGGGSMDVSTDGSATNTTINDGGQMYVSTDGSVTSTIVNIGGFVNLLGGSATDTTLNEGGRMLVNPQGSATGTIINRGGYQEILRSAGAANTIINGGQQSVLSGGSATDTTLNSGGAQYINNGGSATDTTLNSGGAQYINNGGSVTNTTINSGGGQYVYINGNVTKTTITDGGILQVDAGGSASQVTQNSGGAIVTNTSAVLSGTNDKGTFSIAGGSASNMSLENGGLLTVLVGHDASDTTVGSDGTLSVQSGGVLRGTTTLTDNGTLVGNMVTNEGNLYFLNNSAATFAGTLTGTGTLTQEGGNTRFSGLLSQDGGITLHSGAAMTMVTLQANANVTTQSGTSLTLDNGSILTGNVTGDNTGAGDMTVKGASVWHLDGDATVGALTLDNGTVDFRPSATTRLTQAFRPVSLVSESLSGNGTFRMNTDIASHTGDMLNVTGNANGNFVLDIRNTGLEPVSAGTPLQVVHTGSGDAAFSLNGGKVDAGTWEYYLNKENTDWYLKADSSQPGTDNPGTDNPVPPVRHTTKSADAVLDMATAPVYVFNSELQSLRFRHGDVMQNTRSPGGVWGRYTGSDTRISGGAGSGYSLTQSGMETGGDTVFDLNESRLAVGAFVSYSDNSISHNRGGSSTVGSTGGGLYATWFNNDGYYVDGVIKVNRFRNELRTWMSDGTAVKGDYHQNGFGGSLEAGRTFSLNENTWIQPYLRSTAFRAESKDISLDNGMKAKAGTTKSLQGEVGVNLGMNLDVAGTVVRPYLTTAVSHEFSDNNRVRINDSYNFTNDISGTTGKYGAGVSAQLTANAGVWAEASYQNGENTESPVTGSVGFRINF
What is the function of this protein?
A putative autotransporter.
What are the official names of this protein?
Probable autotransporter ROD_p1121, P1121.
What are the subcellular locations of this protein?
Cell outer membrane. Note=The N-terminus is on the cell surface as it is accessible to trypsin.
Protein: FER_TRICV
Sequence: MATYKVTLLSEEHDIDATIDCNDDVFLLDAAEEQGIELPYSCRAGACSTCAGKVTEGDIDQSEQTFLDDDQVGAGFVLTCIAYPKSDCTVLVHQEDELY
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y914_THEMA
Sequence: MWFSGKKEQTIISLFFKHIDKVEETLKCVFDLIKKYLEDTDDIESLYLRTQRLESEADRLRRKTEMEMYSGAFLPNFRGDLLGLIESVDKVANKAEYVADLIVLQKPEVPHELKDLILSQMEYSLKAYESLKSALKFLFEDLERVEEFVLAVEKYEHDEDAVERTALRKLFEMDIERSVKLEVKELIRSIGDIADRTEDVSDRAEIILLKRRF
What are the official names of this protein?
UPF0111 protein TM_0914.
What is the protein family that this protein belongs to?
Belongs to the UPF0111 family.
Protein: ENDA_METBU
Sequence: MRAEIVKDRVLVEKKAINEFYNNGYYGRPKSSGLELTLIEAVYLAFRGKIEVEHEGKVLEFSDLFKEASILQPSFELKYIVYKDLRERGFYVQPGVTDFRVYPRGSHPGKGAAKQFIYVRSERAPMPLRDLLRSLAAAENVRKQMVLAIVDEESDITFYDVKRPRLKGEMKEPLYPDINADATFLEDRVVVWDEEASKTLFENGFYGKPLDSQRLQLSLVESRYLLEKGVLNINNRQDESMDVDAFSKMASEIEPEFNLKSSVYTDLRDKGVVPKTGFKFGSHFRVYSQVESPTKIPHSEYLIHSIPMDHEFTLPVMSRAIRLANSVRKRMLYAILTDDGVDYIDIGRLKM
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
Protein: M2K6_ARATH
Sequence: MVKIKSNLKQLKLSVPAQESPISSFLTASGTFHDGDFLLNQKGLRLTSDEKQSRQSDSKELDFEITAEDLETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQELKINQASSQCPHVVVCYHSFYHNGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVSASLASSMGQRDTFVGTYNYMSPERISGSTYDYSSDIWSLGMSVLECAIGRFPYLESEDQQNPPSFYELLAAIVENPPPTAPSDQFSPEFCSFVSACIQKDPPARASSLDLLSHPFIKKFEDKDIDLGILVGTLEPPVNYLR
What is the function of this protein?
The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis.  MKK6-MPK13 module positively regulates lateral root formation.  Phosphorylates and activates MPK4.  Activates MPK5 and MPK13 in vitro.
What are the official names of this protein?
Mitogen-activated protein kinase kinase 6, AtMKK6, MAP kinase kinase 6, Protein Arabidopsis NQK1 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: VE1_HPV25
Sequence: MADPKGSTSKEGFNDWCILEAECSDIDNDLEQLFDQDTDSDISDLLDENDVEQGNSRELFHLQECQESEEQLQKLKRKYLSPKAVAQLSPRFESISLSPQQKSKRRLFAEQDSGLELTLTNEAEDVSPEVEVPALNSQPVAEGQSGDIDISYTALLRASNNKAILMAKFKEAFGVGFNDLTRQFKSYKTCCNAWVISVYAVHDDLIESSKQLLQQHCDYVWIRGIGAMSLFLVCFKAGKNRGTVHKLMTTMLNVHEKQILSEPPKLRNVAAALFWYKGSMGSGVFTYGSYPDWIAHQTILGHQSAEASTFDLSDMVQWAFDNNYLDEADIAYQYAKLAPDNSNAVAWLAHNNQAKFVRECASMVRFYKKGQMKEMSMSEWIYTKIHEVEGEGQWSTIVQFLRYQQVNFIMFLAALKDLLHSVPKRNCILFYGPPNTGKSAFTMSLIKVLKGRVLSFCNSKSQFWLQPLSECKIALLDDVTDPCWVYMDTYLRNGLDGHYVSLDCKHKAPMQTKFPALLLTSNINVHNEVNYRYLHSRIKGFEFPNPFPMKADNTPQFDLTDQSWKSFFTRLWHQLDLSDQEDEGENGESQRAFQCSTRSANEHL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: YWNH_BACSU
Sequence: MTLRLAEHRDLEAVVAIYNSTIASRMVTADTEPVTPEDRMEWFSGHTESRPLYVAEDENGNVAAWISFETFYGRPAYNKTAEVSIYIDEACRGKGVGSYLLQEALRIAPNLGIRSLMAFIFGHNKPSLKLFEKHGFAEWGLFPGIAEMDGKRYDLKILGRELS
What is the function of this protein?
This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance.  Inactivates PTT by transfer of an acetyl group (By similarity).
What are the official names of this protein?
Putative phosphinothricin acetyltransferase YwnH, PPT N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. PAT/BAR subfamily.
Protein: TIR_ECO5E
Sequence: MPIGNLGHNPNVNNSIPPAPPLPSQTDGAGGRGQLINSTGPLGSRALFTPVRNSMADSGDNRASDVPGLPVNPMRLAASEITLNDGFEVLHDHGPLDTLNRQIGSSVFRVETQEDGKHIAVGQRNGVETSVVLSDQEYARLQSIDPEGKDKFVFTGGRGGAGHAMVTVASDITEARQRILELLEPKGTGESKGAGESKGVGELRESNSGAENTTETQTSTSTSSLRSDPKLWLALGTVATGLIGLAATGIVQALALTPEPDSPTTTDPDAAASATETATRDQLTKEAFQNPDNQKVNIDELGNAIPSGVLKDDVVANIEEQAKAAGEEAKQQAIENNAQAQKKYDEQQAKRQEELKVSSGAGYGLSGALILGGGIGVAVTAALHRKNQPVEQTTTTTTTTTTTSARTVENKPANNTPAQGNVDTPGSEDTMESRRSSMASTSSTFFDTSSIGTVQNPYADVKTSLHDSQVPTSNSNTSVQNMGNTDSVVYSTIQHPPRDTTDNGARLLGNPSAGIQSTYARLALSGGLRHDMGGLTGGSNSAVNTSNNPPAPGSHRFV
What is the function of this protein?
Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection.  The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface.  Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion (By similarity).
What are the official names of this protein?
Translocated intimin receptor Tir, Secreted effector protein Tir.
What is the protein family that this protein belongs to?
Belongs to the Tir receptor family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Secreted via the type III secretion system (TTSS). Released into the host cytoplasm via TTSS and then independently inserts into the plasma membrane from a cytoplasmic location. In host cells, localizes to the tip of the actin pedestal (By similarity).
Protein: CCNA1_CARAU
Sequence: MASRGFAPLSGRQENIMVLGRADGLHALKPGQRVVLGVLTENDQHNRVFGQVSSKYVPALRDASTLDVSTSSATLGVHVVEPVIAQATKPTSFLLPSELLLVDDVVQDLGSGSCMDSSMQSLPEEAAYEDILCVPEYAEDIHRYLRECEVKYRPKPGYMRKQPDITNCMRVILVDWLVEVGEEYKLCSETLFLAVNYLDRFLSCMSVLRGKLQLVGTAAVLLAAKYEEVYPPEVDEFVYITDDTYTKKQLLRMEQHLLRVLAFDMTAPTVHQFLMQYTLEGHICARTVNLALYLSELSLLEVDPFVQYLPSKTAAAAYCLANYTLNGVLWPENLYAFTGYSLAVIIPCLMELHKLHLGAAGRPQQAIQEKYKGSKYCGVSLLEPVESLPLP
What is the function of this protein?
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions.
What are the official names of this protein?
Cyclin-A1, Cyclin-A.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMG_CAMJD
Sequence: MFDVIVIGGGHAGVEASAAAARMGKKTLLLTTLIEQIGAASCNPAIGGLAKGHLVKELDAMGGFMGEITDEAGIQFRILNESKGVAVQGSRVQIDMDKYRIIARNKLLKLPNLEISQEQVSALIVENDKVKGVKTNLENIYFAKKVILTTGTFLNGLIHVGENKLQAGRVGELASVNLGNYLQTLGLKMGRLKTGTCPRVDATSIDFSVLEIQDGDVNPKAFSFRSRNFNPTQLPCYIARTNTTTHEIIKNNFYRAPLFTGQIEGVGPRYCPSIEDKINRFSDKESHHLFIEPQTIDATEYYINGFSTSLPYEVQTQMLHSVKGFENAKITRFGYAIEYDYIEPTELKHTLELKKIKNLYCAGQINGTTGYEEAAVQGFMAGINASLSIDMKEPLILRRDEAYIGVLIDDLVVKGTKEPYRMFTSRAEFRLLLREENAILRLGKYGYVLGLLSEQDFAYIQNIANNLQKGLEFLLSKEFTPNNQNNAFLESLGEDKISSIVNFQKIVARASFDIEKLKKLDPMFETMDNYSLREILNEAKYCHYISMQKAQVEKMKNLSELKIPENFDFKSVSGLSNEVVEKLNHHKPPTIFAASQISGITPAALDILQIYIKMQKKKA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX4_HUMAN
Sequence: MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFASGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDDESWD
What is the function of this protein?
ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202, PubMed:21034600).  Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity).  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity).  Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity).  Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX4, DEAD box protein 4, Vasa homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: P5CR_STAAC
Sequence: MKLVFYGAGNMAQAIFTGIINSSNLDANDIYLTNKSNEQALKAFAEKLGVNYSYDDATLLKDADYVFLGTKPHDFDALATRIKPHITKDNCFISIMAGIPIDYIKQQLECQNPVARIMPNTNAQVGHSVTGISFSNNFDPKSKDEINDLVKAFGSVIEVSEDHLHQVTAITGSGPAFLYHVFEQYVKAGTKLGLEKEQVEESIRNLIIGTSKMIERSDLSMAQLRKNITSKGGTTQAGLDTLSQYDLVSIFEDCLNAAVDRSIELSNIEDQ
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_SALEP
Sequence: MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSTDTQRIIALLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLAIGKSEVRGGVSHEVVLSAIADCQQA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDH23_RAT
Sequence: MKPVKKKKTEEPELEPLCCCEYIDRNGEKNHVAACLCDCQDLDEGCDRWLTCKSLRPETCERITDTISDRLRIPWLRGAKKVNISILPPLVLLPVLLRVASWHFLLGVVVLTSLPMLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLQEVVPQGHVGPAQLALLTCGLFLILVALYRAKKNPGYLSNPACNDKSPSNSQIECPIKKGQEKTKGFPGTDTSGSLNNRTLKDDAKGSSRVGLDSPAKSKEDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILALSIFLLTSVYGISLTLNTICRDRSLFTALFYCPGVYANYSSALSFTCVWYSVIITAGMAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGQYNRGFLRNWLQFSTLGTRTVHTPAEDIV
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes (Probable).  Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane (By similarity).  May be involved in NOS1 regulation and targeting to the synaptic membrane (PubMed:15105416).
What are the official names of this protein?
Palmitoyltransferase ZDHHC23, NNOS-interacting DHHC domain-containing protein with dendritic mRNA, Zinc finger DHHC domain-containing protein 23, DHHC-23, zDHHC23.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Neuronal soma and dendrites.