PharMolix/UniProtQA huggingface dataset:
Protein: QUEC_CHRSD
Sequence: MSDLPRHSPRRQHAGESAVTAITSPEDTTKAVVIYSGGMDSYTVLHRALRAGFEVHALSFHYGQRHSRELETAHDVCQRLGIAHQVVDIRAIHGLIGNSALTDATQTMPDGDYDADNMAATVVPNRNMILLSLAIGHAVNIGANVCFYGAHGGDHVLYPDCRPEFVERMNDVAAIADFTPVRIAAPYLHASKEEILADGLAMGLDYAQTWTCYLGAERSCGHCGSCRERLAAFAAQGVTDPLVYAGAGASD
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: Y4217_MYCMM
Sequence: MHGTDSSSDTPGQPAPSRAELLSAHAEGSISEDTILKTARDRAVDIGVGAVTPAVGALLSMLAKLSGGKAVAEVGTGAGVSGLWLLSGMSDDGVLTTIDIEPEHLRVAKQAFTEAGIGPSRTRLISGRAQEVLTRLADDSYDLVFVDADPIDQPDYVVEGVRLLRSGGVIVVHRAALGGRAGDPAARDAEVTAVREAARLIAEDERLTPALVPLGDGVLAAVRD
What are the official names of this protein?
Putative O-methyltransferase MMAR_4217.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: Y962_TOLAT
Sequence: MAGFRKENDEVWLDVYIQPKASRDQIQGWHGEELKIAITAPPVDGQANAHLIKFLAKQFKVAKSQIVIHKGELGRHKTVRITSPQQLPAILDQSAD
What are the official names of this protein?
UPF0235 protein Tola_0962.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: R15A1_ARATH
Sequence: MVRISVLNDALKSMYNAEKRGKRQVMIRPSSKVIIKFLIVMQKHGYIGEFEYVDDHRSGKIVVELNGRLNKCGVISPRFDVGVKEIEGWTARLLPSRQFGYIVLTTSAGIMDHEEARRKNVGGKVLGFFY
What are the official names of this protein?
40S ribosomal protein S15a-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_MESCR
Sequence: MALRMWASSAANALGVSCAPKSHLLPALSLSRCFSTVLDGLKYASSHEWVKHGGSVATIGITDHAQGHLGDVVFAELPEGGAVSAGKPFASVESVKATSDVNSPISGEIVEVNTKLSDSPGLLNSSPYEEGWMVKVKPSNPAELESLMGSKEYTKFCEEEDAH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPO5_SULIM
Sequence: MRGSSNRKIDPRIHYLVPKHEVLSIDEAYKILKELGIRPEQLPWIRASDPVARSINAKPGDIIRIIRKSQLYGEVVSYRYVISG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y939_STRZT
Sequence: MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEEFGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEILTSIDNRE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein SPT_0939.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: H2B1K_MOUSE
Sequence: MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 1-K.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MURG_DESVV
Sequence: MRRVILTTGGTGGHIFPALAVAEEIRARYPECSVLFMGGLYGPEADLAARAGLDFVGLPVRGVLGRGVRAIGAAFGMAAGIARAYAVMGRFDPDIVLGFGGYAAFAGVLAARLRGRPAAIHEQNSVPGVTNRVLSRVVPRVFLSLPDTLGAFPPQKTCLAGNPVRASIVACGAERSDPRPDHVRRLLVMGGSLGARAINDAVVSSLPALAEAGVEVWHQTGAADWERIRKAYAETGHGEGRVEAFIDDVASAYAWADLVLCRAGATSVAELAVAGKPAVLVPYPFATHDHQTHNARWLVSRGAAVLLEQKDISMTDVPALLVGLLSDRARLNRMAVSARAQGRPDAAAAVVDGLVELLKTTPRAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCL2_COCIM
Sequence: MSAHTTAEQSPKRRRIHLDNDSKMHFSSILEDGTSKSQEALLPPRRARGYQLEMLSESLRQNIIVAMDTGSGKTEIAILRIQRELERCPAHKFVWFMAPTVALVEQQHSAISKQLPAFQTRLLTGAANVSHWSTKKIWDDILLNIRIVISTPQVLLDALSNGFVDLHTISLLVFDEAHHCVRDAPANRIMRDFYHYHRQEEGTDGLPHILGLTASPTTRARQTDLEVLEINLNAVCVTPKMHREEMMQFVHMPEYRSIEYQPDVQNFSSIVEKLSVIINELDIENDPFVKFMRRRNDLKSRQRLLDALENKKTPCLDQLKRCLRRSRVIHRELGPWASERFLTRCIMGLKSKQTNASGPQWADWDREDNSYMLNVLSQVVSSTEMGVQNPPDELSRKVHKLIDFLVLEHVNGSIGIVFAEERTIVIMLAQLLSLHPRTKHIKTTAFLGSSASVSRKSDITELHNPIDQSTAIDDLRTGKKDLIIATAVLEEGIDVPICDLVICFDLPKDLRSFIQRRGRARKKGSKFALFLHSEDRATSSELHLMEKTMKQLYLENKRALEHIQYLENVEEEGYDGFRVASTGALLTLSNARNHLSHFCGTLSAEFIATDPEFVLEGDDTTGFSAKVILPSFLDPKLREFRGILLWKTEKMAKRDASFQAYVALYEAGLVNDYLMPAHHHIDDEDGLEQVEKRPSFAKALGSLNPWAAIAKKWREAKHFYQNLIEISAGAQAFPPMVMVLPVELPCDISFRLFWNEHSTLLVSVKRGGQDFAADLIRLAADTTSILLSSLFSQKMVPGSLDFSWLFLPQMESIPSAIREWCDSVTGTISLHDIRDCDMAGFENPGLVRPMDNTARPCTFEKLVWRKYVPAETSDGASLSEQVTYDREVPHIEGRVWPKRTDFLHRLEPSNTSKAHHTAKCFYPANNCSVDRLPVEYSQFALFIPCLIHSIENYFIANELAQTILHPVGFSNLSLVLTAISSSAAREASNYQRLEFLGDSLLKLHTSIQLAADHPLWPEGRLTMRKGNIVSNGYLANAALQTGLDKFILTKPFTGAKWRPSYNTDHINTGDMTEPTREMSTKVLADVVEALIGAANIDGGENKILNCLKIFIPDIKWSPLNECVNILHHQEDSFSDENNNMLSEIEGLVGYTFKKKPLLLAAVTHPSSKGSGHSYQRLEFVGDSILDIIVVQELFESPRCFHHFDMHLMRTALVNADFLAFLCMNAYREEDRGEAVENSKRRVTVAMTKRRAYLWGFMKHSASWDIVNAQQRAAKQYEKLHEEIDEKLRSSKTYPWTLLCRLDAAKFFSDIVESILGAIFIDSQGSMPACRIFLERIGLIPYLKRVLSEDLDLMHPKERLGLLAGTLSVKYETKRTQGVEPQRWECAARVGDEEVVRVDCRVSRVDAETTAAEAAVAILKTRKLQSEASNKVAECD
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: RIMP_YERPN
Sequence: MSTLEQKLTEIISAPVEALGYELVGIEFIRGRQSTLRIYIDSDDGITVDACADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPMFTAEHYTRYLGEEVTLVLRMAMQNRRKWQGIIKAVDGEMITVTVDGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT2_MONDO
Sequence: MNSSSLFGIWLSVPLILSWVTPQVSSSWWYMRAVGSSRVMCDNVPGLVSRQRQLCHRHPEVMRSIGLGVAEWTAECQHQFRQHRWNCHTLDRDHNLFGKVLLRSSREAAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTSKDSKGTFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWKKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSRVTRMTKCECKFHWCCAVRCQDCLEVVDVHTCKAPKSPDWVAPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity).  Functions as upstream regulator of FGF10 expression.  Plays an important role in embryonic lung development.  May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: WIS4_SCHPO
Sequence: MGLEHTFYPAEDRFEPLLEHSEPVNFVPKENAKSYVRQGFASPHQSLMDNLVDSTESTKRSENFVSHIPLTPSHSGQSEKLMSTRTSHSPYISPTMSYTNHSPANLTRNSSFNHQHYSTTLRSPPSMRGRGIDVNSSHYPHISRPRTSSDSQKMYTRAPVDYYYIQENPYFNNIDQDSISDKSLPSTNQSLHHSEEDTESDNDFSESIHPEFDIDVFYKVSNILYDESDLQDPEKRERLEWHSMLSSVLKGDVMQTEKRRLRLTEPDGHSGTYISEVWLGLQAWLHGRLNADQAEVIRKSREGVEPVLREVIDFQIQDEETTKPPLEQVTEILEKVEQCKQFYISSREMEENVPLSASKEFNYKLNALISWSNVMESIQVETLVLQKWVGNDEFDLTMRTPQFNYDGVENTSSFVERIFRQSGLQRTFEQRTLTTLNRIIHQAKQTISENAQAFEEMKLPTYEDKLLPLVRFPIKLLEEALRLRLAYAKKIKGPNFLIVDSMLDDFKIALSVAVRIKREYIKIASPSPGWSLPTNVDEDYDNVLLDSLKFYFKLLTLKLSSGNKNLYFKEIDFLENEWAFLNEHIYWINGGDIHMAGQFSYLSNSLLLNVHRYVESHLNGPTERTAASLTNWYSTLLKNTQIRFRKILRFSETLNSRFENASDFVISEGHLPDLVNRLSTTGHFLAYTANLERDGVFVIADHTLSENPEALKALLFSKDISNLETIQQNCSYVLILCPVHPIVWKGRIEKVDVPDFSVDLKTNRVRIIASNKREHLQAAKSVFQSISGDLVTLAVECRSSITRVYKEFIRLSKLCMRISSTVVDCVSAVREACSGVNCHDLIYHVFSFAAEFGQRILRFLSFDSYWQTKLKRKITSLAVEWISFICDECDLMDRKTFRWGVGALEFLMLMIRGNNILLIDDAMFLKIREKVGKSMAFLLTHFDVLGAKSKVAAKLQRESTEVSSSPRLTSFGDVEEEALSIQLLQKETMLRIDELEIERNNTLLERLAIGHVLDDSVFRNRDFIKLASSFSNITIRWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSIPQNEKISSLARDFIEQCFERDPEQRPRAVDLLTHPWITDFRKKTIITMPPATITKKTSLSHTITEEKTAQLLAGRHDDSKAETDSLAASYKEESALPVASNVGLRQPNELRIDSINLPPAIVTPDTINYSVD
What is the function of this protein?
Involved in a signal transduction pathway that is activated in under conditions of heat shock, oxidative stress or limited nutrition.  Unlike win1, it is not activated by changes in the osmolarity of the extracellular environment.  Activates the wis1 MAP kinase kinase by phosphorylation.
What are the official names of this protein?
MAP kinase kinase kinase wis4, MAP kinase kinase kinase wak1, MAP kinase kinase kinase wik1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: RL27_GEOUR
Sequence: MAHKKGVGSTRNGRDSDGQRLGCKKFGGEHVKAGNIIYRQHGTKIHPGNNVGLGRDYTLFALIEGVVKFERMGRDRKKVSVYPAN
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PYRG_PORGI
Sequence: MADTKYIFVTGGVVSSLGKGIVAASLGKLLQARGFNVALQKFDPYINIDPGTLNPYEHGECYVTEDGHEADLDLGHYERFLNTPTTRANNITTGRIYQNVIRKERKGEYLGKTVQVVPHITDEIKRNVKLLGQKSQYDFVITEIGGTVGDIESLPFLESVRQLKWELGQNCLCVHLTYVPYIAAAGEVKTKPTQHSVKQLQEVGIQPDILVLRTEHELQPDILKKVALFCNVAPDSVVQSVDVPTIYEVPLVLQQQHMDETVLRKVGLQVGPVPEMRQWHEFLEMKHTARETVTIALVGKYVELQDAYKSIDESLMQAAIYNRKKLNLISVHSEKVTEANVAETLKDMDGIVIAPGFGSRGVEGKLIALKYARENDLPTLGICLGMQCMVIEYARNVLGFKDANTTEIESNIEHKVIDLMDEQKTVTDMGGSMRLGAYDCALRKGSKLAAAYGKEFVRERHRHRFEFNSQYREAFEKAGMQCVGENPETGLVEAVEVPACRWFVGVQFHPEYNSTVVNPNPLFMAFIREAIKTRKKDKE
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: F16PC_LACLM
Sequence: MDKKYYQLLKKQFSSKEAVLTEIINLSAICELPKATEHFMSDVHGEYDAFNHVLRNGSGSIKEKLRDCFPQFSSAEISSVATLIYYPQEKLDSECQLQDKKLFEHYCRLNLVYLLKTVKFVGQKYTRSKVRKAFPEKFRYILEELINEVDSTTDKQDYFDSILSQLQNLGELTRLIVALADTIRRLTVDHLHVVGDIYDRGPYPDKIIDRLINMPSVDVQWGNHDIVWMAAFSGSPLAMMNVIRICARYGNLDILEESYGINLRAILEYAERYYEPSEAFRPRLVDGVRLSADEKALLNKLQQTTAILQFKLESQLIERRPDFQLEHRDLLHFIDFSQNKIELAGETYDLIDFQAPTINPEQPASLTEEEEKIIAHLLNNFKTSDKLKRHVGFLQEKGAMYLSYNGNLLIHGCLPLHENGDFKSFTIDKKAYAGRDLLDFFDSEVRKCLAHPEESEDLATDLMWYLWVGECSSLFGKTAMTTFERYYIKDKSTHVEKKNPYYQLREQPKIITKILENFGLDENGHLVNGHTPIKEKNGENPIKADGKLIVIDGGFAKAYQKETGIAGYTLLYNSFGIQLVAHQPFSTVKAAVEKGTDIISLKRLVAEVDERKRVKDTNVGQTLLSEIADLEVLFEHYEDY
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: 2SS4_ARATH
Sequence: MANKLFLVCAALALCFILTNASVYRTVVEFDEDDASNPIGPIQKCQKEFQQDQHLRACQRWMRKQMWQGRGGGPSLDDEFDMEDDIENPQRRQLLQKCCSELRQEEPVCVCPTLRQAAKAVRFQGQQHQPEQVRKIYQAAKYLPNICKIQQVGVCPFQIPSIPSYY
What is the function of this protein?
This is a 2S seed storage protein.
What are the official names of this protein?
2S seed storage protein 4, 2S albumin storage protein, NWMU2-2S albumin 4.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: TMEDA_TAKRU
Sequence: MARLTALLFLPVLIESAFSISFFLPVNTRKCLREEIHKDVLVTGEYEISEQVVTVHTSSTVVGDGSIFKITDSSSHTLYSKEDATKGKFAFTTEDYDMFEVCFESKCTGRVPDQLVNLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE
What is the function of this protein?
Involved in vesicular protein trafficking.  Mainly functions in the early secretory pathway.  Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side (By similarity).
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 10, S31III125, Transmembrane protein Tmp21, p24 family protein delta-1, p24delta1.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type I membrane protein.
Protein: UBA5_XENTR
Sequence: MEKLIEELRSRVSELEEELHRVRNGEQVHEGHRAKINTMSAEVVDSNPYSRLMALKRMGIVEDYEKIRTFTVAVVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVEMANMNRLFFQPHQAGLSKVEAAEHTLRNINPDVQFEVHNYNITTLDNFQHFMDRISKGGLKEGTPVDLVLSCVDNFEARMAINTACNELVQIWMESGVSENAVSGHIQLIKPGETACFACAPPLVVAANIDEKTLKREGVCAASLPTTMGVVAGMLVQNVLKYLLNFGTVSFYLGYNAMQDFFPTMAMKPNPQCGDKYCRKQQEEFKLKEAARPKQEPIVVKEEEIVHEDNDWGIELVSEVSEEELKAASGPVPELPEGIKVAYTVPITEPTSGFIVEDSEQSLDELMAQMKNL
What is the function of this protein?
E1-like enzyme which specifically catalyzes the first step in ufmylation.  Activates ufm1 by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ufm1-E1 thioester and free AMP.  Activates ufm1 via a trans-binding mechanism, in which ufm1 interacts with distinct sites in both subunits of the uba5 homodimer.  Trans-binding also promotes stabilization of the uba5 homodimer, and enhances ATP-binding.  Transfer of ufm1 from uba5 to the E2-like enzyme UFC1 also takes place using a trans mechanism.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5, UFM1-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Golgi apparatus.
Protein: ZN687_MOUSE
Sequence: MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGQGKPEPSVGGDSKDREEAAAAENDPESPAEASDHGLPQPPDTSTVSVIVKNTVCPEQSESLTGDSGEEETKAGGITKEGPVGSCLMQNGFGGPEPSLSENPHSSAHASGNAWKDKAVEGKTCLDLFAHFGSEPGDHPDPLPPEPSQPRGGDMAPPPFSTPFELAPENGSTLLPPASLLPQGALKQESCSPHHSQGLTQRGPGSSPETAGIPASVSPPQVAGVSFKQSPGHQSPPASPVKAPSCKPLKEEDEGTVDKSPPRSPQSPSSGAEAADEDSNDSPTSSSSSRPLKVRIKTIKTSCGNITRTVTRVPSEPDPPAPLAEGAFLAETSFLKLSPVTPTPEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGNATSPKTMTKSVLGLVPQTLPKAEVRTGFSLGGQKVNGASVVMVQPSKSATGPGTAGGSVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVPGPLALPVLGKGEGAVTSSTITTVATEAPVLPLPTEPPAPPTASVYTCFRCLECKEQCRDKAGMAAHFQQLGPPALGSTSNVCPSCPMMLPNRCSFSAHQRTHKNRAPHVCPECGGNFLQANFQTHLREACLHFSRRVGYRCPSCAVVFGGVNSIKSHIQASHCEVFHKCPICPMAFKSAPSAHAHLYSQHPSFLTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRVGEEAVGKGAGGALLTPKTEPEELAVSQAEAAPATEESSSSSEEELPSSPEPPRPTKRARRGELGNKGIKGGGGGPGGWTCGLCHSWCPERDEYVTHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLPLGTQSSGRGGSLARGSGGRAQGPGRKRRQSSDSCSEEPDSTTPPAKSLRGGPGSGGHGPLRYRSSGSAEQSLVGLRVDGGTQQCLDCGLCFASPGSLSRHRFISHKKRRAGGKASVLGLGDGEEAAPPLRSDPEGGDSPLPAPGDPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGGSGDN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 687.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly nuclear.
Protein: RS14_CERS5
Sequence: MAKKSMIEREIKRAKMVQQYAAKRASLKEITTNADLPMEQRFKAQLKLAELPRNSSATRIHNRCQLTGRPHAYYRKLKLSRIMLRELASFGQIPGMVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TRXB_YARLI
Sequence: MTHSPVVIIGSGPAAHTAAIYLSRAEIKPTLYEGMMANGIAAGGQLTTTTEIENFPGFPDGIMGSQLMEDMRKQSIRFGTEIITETVSKVDLSQRPFKYWTEFNEDEEPHTADAIILATGASAKRLSLPGEDQYWQQGISACAVCDGAVPIFRNKPLAVVGGGDSAAEEALFLTKYGSKVYVIVRKDKLRASAVMAKRLASHPKVEILFNHVSIEAKGDGKLLNALEIENTLTGEKRDLEVNGLFYAIGHIPATSIVKGQVETDEEGYVVTVPGTANTSVKGVFAAGDVQDKRYRQAITSAGTGCMAALDCEKLLAEEE
What are the official names of this protein?
Thioredoxin reductase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_ACIBT
Sequence: MSHISVLLFETVESLLADRTTGVYIDATFGRGGHTRLLLSKLDENARVYAFDKDPQALEVAAALAQEDPRFTIIHASFADIKEKMQEIGVQSVDGIMADLGVSSPQLDQAERGFSFMQDGPLDMRMDNSKGLTAAEWLLEVEEEDLANIIYQYGEERYSRRIARAIKQAGKLDTTAQLAEIVKTAHPKWEKHKHPATRTFQAIRIAINKELDDIEVFLPQAVDLLKPKGRLSVISFHSLEDRLIKQFIQKESTLAEDSGWGMPQQQVDTRRLKKISRVRASEEEVKANPRSRSAWLRVAERLEQKGA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_PARP8
Sequence: MSRTLSKPAGGSLAPWLGVAVIVILFDQLTKIAVAKVFAYGSSHAIAPFFNLVLVYNRGAAFSFLAMAGGWQRWAFTALGVAAAVLICYLLKRHGTQKMFCTALALIMGGAIGNVIDRLLYGHVIDFLDFHVGAWHWPAFNLADSAITIGAALLVFDELRRVRGAR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEP3_ARTBC
Sequence: MHGLLLAGLLALPMNVLAHPAEQHASNVLSRRGVDIESFRLPLKAKYMDSDATAQKIQAMSFSKDDDYVSTATKLVKSTFPKSTFRVVDDHYIGTNGIGHVHFKQTAHGLDIDNSDFNVNIGRDGKVFSFGNSFFTGEIPKENPMVKRAFSDPVKALKGAVKALNLPVKSDNAKAKTAAGKESFEFMGTTGALSAPKANLVYLQKEDGSLALTWKVETDVGDNWLLTYVDAHNSETVHNVVDYVASAEYKVFAWGLNDPTEGNPTSIRDPWTDASPYTWNSDGMTKYPTTRGNNAIAQDNPTGGSTYINNYRPQSPNLIFSYPWSPTATPPSSYKDFSITQLFYTTNRYHDLLYSFGFNEAAGNFQVNNGNKGGKGNDFAIVNAQDGSGTNNANFATPPDGSPGRMRMYNWTTARPNRDGCLEAGIVIHEYTHGLSNRLCGGPANSACLNALESGGMGEGWGDFYATAIRLKPRDTKDTNYSMGAWAANNPKGIRAYLYSTNLQTNPYMYTSVNSLREVHQIGTVWASMLYDLMWALIEAHGGTYSADPVFRNGVPQDGRHLTMKLVMDGMALQPCNPNFVQARDAILDADRALTNSANKCTIWKAFAKRGLGYGAKYDARNRTGSNKLPPGC
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Probable extracellular metalloproteinase 3, Fungalysin MEP3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_ECOLC
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSYGSPSLESAVDELLAEHVDHIVVLPLYPQYSCSTVGAVWDELARILARKRSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_MARSD
Sequence: MDFNIEEVSAVEREIKVSVPAEEVGAALDATVALYKVQTPVKGFRKGKVPASVIQSKYKKQIINEATTDLINYQINDILNGQSLVPVSKIDVDAKELVRGEDFSYVIKFEIVPEFDTPGYLGLPVEEERAEVTEDELKEVENRLLQSMAKIAPIEDDRPAKDGELASVTFSAEMDGEPIPGVQADNFDLPIGEGHSLEEFEEFVKTLKAGESGETDITFPEDFINSDLAGKTATMKVTVHAVKERKMPELTDDVVKQAGGFESVEKMREIVKQSYTANRKQLNKSAAQTKLISGIVKELDFPLPPSLMEDRLQRMVADVIGRAERSGKSFESLGKSMEELREEQRPVAEESVRTEIFLLNVAKREELSVEPQEVEGALYQIAQQTQQDLSSVKSYYEENNLIVPLKDRLLADKAAEFIYENADVTEIDPVKKDDK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.