PharMolix/UniProtQA huggingface dataset:
Protein: THIC_BACMK
Sequence: MKQSVSAEQIELKSSLPGSKKVYVDGTREGMKVPMREIEQSDTNGVQNPPIRVYDTSGPYTDPEYKVELEKGLQAPRHSWTLGRGDVEAYEGREIKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVSQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRMTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAVEFKETGSHLYQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: GCSH_RHOBA
Sequence: MARDPSTLRYAETHEWVDVQEEGGDKFATIGISAFAVEQLNDLVYMDLPEVGRTLEVGEEFGEVESVKAVSPLYSPVAGEVVAVHTDLPDNLDNLNDDAFDFGWILKVKLSADLPETLMDFAAYQKQCSEAG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RIMP_SALNS
Sequence: MGVGLSTLEQKLTEMITAPVEALGYELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPISVAYNLEVSSPGLDRPMFTADHYARFQGEEVALVLRMAVQNRRKWQGIIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKIPA_ORYSJ
Sequence: MASLKELLPTPKAAASTFYDHSSDPWFKERYGGESAQSDAAAAAAKPSGPAKPVPPYGKRGGFVPRRPEDFGDGGAFPEIHVAQYPLGMGRRDEKGGSKILALTVDAKGSVAFDAVVKQGENASKIVYSKHSDLVPKIATADSEATADDEEYQKQIEETTERTKAALEKVVNVRLSAAQPKNVPTHDSESKFIKYKPSQQSAAFNSGAKERIIRMSEMAQDPLEPPKFKHKRVPRASGSPPVPVMHSPPRPVTVKDQQDWKIPPCISNWKNPKGYTIPLDKRLAADGRGLQEVQINDNFAKLSEALYVAEQKAREAVQMRSKVQRELQLKEKERKEQELRALAQKARMERTGAPPAPTGVPAGGGRGAVDDREEDMDLEQPREQRRESREEREARIERDRIREERRRERERERRLEARDAAMGKKSKLTRDRDRDVSEKIALGMASTGGAKGGEVMYDQRLFNQDKGMDSGFATDDQYNIYSKGLFTAQPTLSTLYRPKKDGDSDVYGDADEQLEKVMKTDRFKPDKGFSGASERSGKRDRPVEFDKQEENDPFGLDQFLTEVKKGKKAVEKIGSGGAMRASGGSSMRDDYEGGGSGRSRINFERGR
What is the function of this protein?
Acts as positive regulator of drought and salt tolerance.  Acts as positive regulator of cell viability.
What are the official names of this protein?
SNW/SKI-interacting protein A, OsSKIPa.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COMB_SYNPW
Sequence: MQVSYFHVAADVPDAIGSVEGPDAAVVIDVLRATTTIAWALHNGAEAVQAFADLDELRLQSRNWPEQTRLLLGERGGRMLEGFDLGNSPVAVIPEVVQGKRLFMSTTNGTRALQRVRDVSVVMTVALPNRQAVAQRLLRDQPERVWMVGSGWEGTYSLEDSLAAGALADALVAAGAQVANDELQAALALWAQWKHDPEACLRVASHGQRLTRLGNHDADFSCCAGLDQLSVVPTQTEPGVLRAIRV
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: PROB2_PSET1
Sequence: MQRDQVIVVKLGTSVLTGGTDKLDKAHMVELVRQCCELKKQGHHVILVSSGAVAAGREQLLKPCGRSVIDKQMLAAVGQGQLIHIWQSLFALYGVNVGQMLLTRADVNDRERYLNARDTLNALLNYDVVPIINENDAVATSEIKVGDNDNLSALVAILANANKLLLLTDQEGLFTSDPRTNADATLIGEVSDINDELRQLAGGSGTNLGTGGMATKLQAADIARRAGVEVIIAKGAGKNVILKCMSEQLPGTRFLKLTAPKEGRKKWLLAGPKSSGQIVIDAGAITALQTKGASLLAKGVTNALGAFERGDLISVINSDKQLIARGLTRFSSSEVNKIKGAHSKQIGELLDYDGGAEVLHRDDLILL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase 2, Gamma-glutamyl kinase 2, GK 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C81F3_ARATH
Sequence: MFYYVIVLPLALFLLAYKLFFTSKTKRFNLPPSPPYSLPILGHHNLLKPPVHRLFHRLSKTHGPIFSLQFGSRRAVVISSSSLATQCFTGQNDIILSNRPCFLTAKYVAYNYTTVGTAPYGDHWRNLRRICSLEILSSNRLTNFLHIRKDEIHRMLTRLSRDVNKEIELEPLLSDLTFNNIVRMVTGKRYYGDEVHNEEEANVFKKLVADINDCSGARHPGDYLPFMKMFGGSFEKKVKALAEAMDEILQRLLEECKRDKDGNTMVNHLLSLQQNEPEYYTDVTIKGLMLGMMIAGTDTSAVTLEWAMSSLLNHPEALEKAKLEIDEKIGQERLIDEPDIANLPYLQNIVSETFRLYPAAPLLVPRSPTEDIKVGGYDVPRGTMVMVNAWAIHRDPELWNEPEKFKPERFNGGEGGGRGEDVHKLMPFGNGRRSCPGAGLGQKIVTLALGSLIQCFDWQKVNGEAIDMTETPGMAMRKKIPLSALCQSRPIMSKLQAHLKG
What is the function of this protein?
Involved in indole glucosinolate biosynthesis.  Catalyzes hydroxylation reactions of the glucosinolate indole ring.  Converts indol-3-yl-methylglucosinolate (I3M) to 4-hydroxy-indol-3-yl-methylglucosinolate (4OH-I3M) and/or 1-hydroxy-indol-3-yl-methylglucosinolate (1OH-I3M) intermediates.  These hydroxy intermediates are converted to 4-methoxy-indol-3-yl-methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl-methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2).
What are the official names of this protein?
Cytochrome P450 81F3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYR_PARD8
Sequence: MVIEQQITGAIIAGIKELYGADVTASQVQLQKTKKEFKGHLTLVVFPFLRMSKKSPEQTAQEIGEYLLRNEPAVAEFNVIKGFLNLTVACSCWIDLLNSINEQPAYGIIPVTEQSPLVMIEYSSPNTNKPLHLGHVRNNLLGYSLSKIIKANGNQIVKTNIVNDRGIHICKSMLAWQKWGNGATPESTGKKGDHLIGDFYVLFSNKLKEETHALEAKGLTKEEAEAQSTLMAEAREMLRKWEAGDKEVRALWEMMNNWVYAGFNETYKMMGVDFDKIYYESQTYLEGKGKVMEGLEKGIFYRREDGSVWADLTKDGLDEKLLLRADGTSVYMTQDIGTAKLRFDDYPINKMIYVVGNEQNYHFQVLSILLDKLGFEFGKGLVHFSYGMVELPEGKMKSREGTVVDADDLMAEMISTAREISQELGKLDEMTPEEAENIARIVGLGSLKYFILKVDPRKNMTFNPKESIDFNGNTGPFIQYTYARIRSVLRKAAEQGIVLPEQLPLTFAISEKEENLIQMIADYAEIVKEAGKLYSPACVANYIYDLVKEYNQFYHDFSILREENPELKNFRLVLSANVAKIVKSGMDLLGIEVPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_VIBA3
Sequence: MRIAILSRNENLYSTSRLKAAGEARGHQVDVIDTLHCDIDIASNNPKIRYMGEELPQYDAVIPRIGASITFYGTAVVRQFEMMGTFCINESVAISRSRDKLRSLQLLSRKGIGLPKTGFASRPDKIQDLIKNVGGAPLVIKLLEGTQGIGVVLAETNKAAESVIEAFMGLKANILVQEFIEEANGADIRCFVVGNKVIAAMKRQAGEGEFRSNLHRGGTAQLVKLTKEERATAINAAKIMGLNLCGVDILQSKNGPVVMEVNSSPGLEGIEKSTGKDVADMIFEFIEKNAKPNANRTRGKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: GPTC4_MOUSE
Sequence: MSVTPEVKSRGMKFAEEQLLKHGWTQGKGLGRRENGITQALKVTLKQDNHGVGHDPAKEFTDHWWSDLFNKTAASLVVDSGKDGVQIRRLSKETTQRSHPKPSLLYQKFVKTATLTSGEEKPDRDLGNCSDVDNHEPTPPKILTDEMLLKACEGRTAHKAARIGITMKAKLARLEAQEQAFLAQLKGSKALGTSQPLTDSEPSQKKKKKRKQKEGEEAATTEKSLGDELLGHTDRSFRDSRKKKKRQKAERQGTAIGSEEEEAAGESGPRELSTEQSDQPSRKKKKRRKQRHEEDGEMGVCDEGGRDVTSRPKAVNSGGDKDPRRSSKKRGTCGEDLDTQEEEGKDDLTKGERKVRRKDKRKRQQCCEEDLDVSSKDDGGTWVAEDAGERSRQYPKERAKKKKRKRDRGSEVDLS
What are the official names of this protein?
G patch domain-containing protein 4.
Protein: LEXA_PECCC
Sequence: MKVLTARQQQVYDLIRDHIAQTGMPPTRAEIAQQLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLMEEETGIPLVGRVAAGEPLLAQEHIECRYQVDPAMFKPSADFLLRVSGMSMKNIGIMDGDLLAVHKTEDVRNGQIVVARIDDEVTVKRLKKQGNTVHLLAENEEFAPIVVDLRQQSFSIEGLAVGVIRNSDWS
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: NOC2L_DROME
Sequence: MKLATKKIKTLGKSKPDLSKKKPAKDAIRKTKPQTTSETKVTPRNPKQKVAEPVKNGKTTKKGFKKSHKEELEGLKDIDPEFYDFLKNNDKKLLDFNLLDTDDDDDEEGDEEDKEDTVTKESKDDEDDEEKYHKPSKDLEVASDESDFEVDEEDDAAAGGIQKITLNLLHQWEQQLGQANISIDIVRKVIQAFNSALASISADGADGGENKHNAAAFKVVGAAAFNGVIQLCVIHLQPAIIRLLGVRPNSSLPLHKHKKWVKVRGCLRYYLTDLIRLVEQVSSPNILGVLLKHLHQMAGMVVPFSALGKTILKRLVVLWSTGDETVRVLAFLCILKITRKQQATMLNHVLKAMYLAYVRNSKFVSPNTLPGINFMRRSLVEMFALDLNVSYQHVFLYIRQLAIHLRNAVILKKKDSFQAVYNWQFINSLRLWADLLGASANKPQLQPLIYPLVTIATGVIRLIPTAQYFPLRFHCLQTLISLAKETNTYVPVLPLIVEVLKSNTFNRKHSAVSMKPVQFTCVLRLNKGQLAENGFRDEVIEQVCGLLLEYLAHESTSLAFSDLVVPTVMAIKTYLKECRNANYARKLKQLLEKIQESARFIEQQRGKSSVTFDIKDAQAVAAWEQQLRLKRTPLDVYYASWLKTHETKKRRQAAHTDEINADYDVPKLKKLPVKTGVPVRNENGEVELFPSDSEDEGDDGLHLGSDDDDDEDVQEEEEVEVEHPKAKKAKKEKPEKQKPRPATVEDDYDEAGGAVDIVKDLDLNEW
What are the official names of this protein?
Nucleolar complex protein 2 homolog, Protein NOC2 homolog.
What is the protein family that this protein belongs to?
Belongs to the NOC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_STRA1
Sequence: MAGHEVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDAGLKEVFEDVLPISNFTDTMDLEFVGYELKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDAKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGDSELVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLVARFFDPRRYDLAAVGRYKINKKLNLKTRLLNQTIAENLVDGETGEILVEAGTVMTRDVIDSIAEHIDGDLNKFVYTPNDYAVVTEPVILQKFKVVAPTDPDRVVTIVGNSNPEDKVRALTPADILAEMSYFLNLAEGIGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRSTGAVTNEIVWLTADEEDEFTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFPSSIVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAKHDGRVIFSDAEKVEVRREDGSLDVYHVQKFRRSNSGTAYNQRTLVKVGDLVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEDSLRDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGVVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWETVQEAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDVMHVDDLEKARVKQEAEEKQAEQVSEVVQED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SAC1_HUMAN
Sequence: MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID
What is the function of this protein?
Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 4-phosphate (PtdIns(4)P) (PubMed:24209621, PubMed:27044890, PubMed:29461204, PubMed:30659099).  Can also catalyze the hydrolysis of phosphatidylinositol 3-phosphate (PtdIns(3)P) and has low activity towards phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).  Shows a very robust PtdIns(4)P phosphatase activity when it binds PtdIns(4)P in a 'cis' configuration in the cellular environment, with much less activity seen when it binds PtdIns(4)P in 'trans' configuration (PubMed:29461204, PubMed:24209621, PubMed:30659099).  PtdIns(4)P phosphatase activity (when it binds PtdIns(4)P in 'trans' configuration) is enhanced in the presence of PLEKHA3 (PubMed:30659099).
What are the official names of this protein?
Phosphatidylinositol-3-phosphatase SAC1, Phosphatidylinositol-4-phosphate phosphatase, Suppressor of actin mutations 1-like protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane. Note=Trafficking between the ER and Golgi is regulated by nutrient status and by TMEM39A (PubMed:31806350). Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS) in the presence of phosphatidylinositol-4,5-bisphosphate (PubMed:27044890).
Protein: PDXH_BURM9
Sequence: MTTLADLRTNYSRASLDAADVNPNPFVQFDVWFKEALDAQLPEPNTMTLATVDESGRPSARIVLIKGADERGFVFFTNYESRKGRELAHNPNAALLFYWIELERQVRVEGRIEKTSEEESDRYFASRPLGSRIGAWASEQSAVIESRALLEAREKEIGARFGENPPRPPHWGGYRLVPSSIEFWQGRPSRLHDRLLYTRDAASASGWKITRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: ISPD_BOVIN
Sequence: MELGPPGGSGPAEPGPRLRGLRGADAAASASSLSRFGAEAGCRASAVAAVLPAGGSGERMGVPTPKQFCPILERPLISYTLQALERVSWIKDIIVAVTRENMETMKGIIQRYQHKRISLVEAGVTRHRSIFNGLKALAEDQPNCRLSKPEVVIIHDAVRPFVEEDVLLKVVTAAQEHGASGAIRPLVSTVISPSADSCLDHSLERARYRASEMPQAFLFDVIYDAYQQCSDYDLEFGTECLHLALKYSHIKAKLVEGSPDLWKVTYKRDLYAAESIIKERISQKVCVVMDTKEDEEHVGHCLEEMLKTELNHVKVTSGQDLQQIILEQCYNFVCVNVMTSDFEETQRLLNMVEESNLSILYPVVVISVHFLDYESVPLGQKMEKVMQIREFAKEAKKRNILLSGLLIYFPQEEQKLRESLRQGTTIISALIKERNSGLIGQLLVA
What is the function of this protein?
Cytidylyltransferase required for protein O-linked mannosylation (By similarity).  Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate (By similarity).  CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).  Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively.  Not involved in dolichol production (By similarity).
What are the official names of this protein?
D-ribitol-5-phosphate cytidylyltransferase, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein, Isoprenoid synthase domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: AMD_RAT
Sequence: MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFSNECLGTIGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGEKVVNADISCQYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTCTKNVAPDMFRTIPAEANIPIPVKPDMVMMHGHHKEAENKEKSALMQQPKQGEEEVLEQGDFYSLLSKLLGEREDVHVHKYNPTEKTESGSDLVAEIANVVQKKDLGRSDAREGAEHEEWGNAILVRDRIHRFHQLESTLRPAESRAFSFQQPGEGPWEPEPSGDFHVEEELDWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLDPHSKEGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFVTQWGEESSGSSPRPGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKEAEAVVEPKVENKPTSSELQKMQEKQKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRWKKSRAFGDHDRKLESSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGTESEEEYSAPLPKPAPSS
What is the function of this protein?
Bifunctional enzyme that catalyzes the post-translational modification of inactive peptidylglycine precursors to the corresponding bioactive alpha-amidated peptides, a terminal modification in biosynthesis of many neural and endocrine peptides (By similarity).  Alpha-amidation involves two sequential reactions, both of which are catalyzed by separate catalytic domains of the enzyme.  The first step, catalyzed by peptidyl alpha-hydroxylating monooxygenase (PHM) domain, is the copper-, ascorbate-, and O2- dependent stereospecific hydroxylation (with S stereochemistry) at the alpha-carbon (C-alpha) of the C-terminal glycine of the peptidylglycine substrate (PubMed:10079066).  The second step, catalyzed by the peptidylglycine amidoglycolate lyase (PAL) domain, is the zinc-dependent cleavage of the N-C-alpha bond, producing the alpha-amidated peptide and glyoxylate (PubMed:10079066).  Similarly, catalyzes the two-step conversion of an N-fatty acylglycine to a primary fatty acid amide and glyoxylate (PubMed:10079066).
What are the official names of this protein?
Peptidylglycine alpha-amidating monooxygenase, PAM.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein. Note=Secretory granules.
Protein: RL10_AGRRK
Sequence: MERAEKREFVTELNEVFKASGSVVVAHYAGATVAQMNDFRSKMRAAGGTVKVAKNRLAKIALQGTDAEGISNLFTGQTLIAYSTDPITAPKVVVDFAKGNDKIVVLGGAMGTTTLNADGVKSLATLPSLDELRAKLLGMIQTPATRIAGVVAAPASQLARVFSAYAKKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: YPVA_BACSU
Sequence: MTTSRLPFSLTKTKNFYEELNNWIGDVFYDILPEKGFDLRDEQVFMAFQLERAFKEKKVMFAEAGVGTGKTLVYLLFAISYARYVGKPAIIACADETLIEQLVKKEGDISKLAEHLDLKIDTRLSKSHEQYLCLKKLEKTMQRSDDDKWLDLYESLPSFVHESQAMQRFYPYGDRKQYANLSNEEWSDVSYDSFQDCLTCDMRHRCGLTLSRDYYRKSTDLIICSHDFYMEHVWTEESRKREGQLPLLPDHSAVVFDEGHLLEFAAQKALTYRVKQSTLELFLERLLQNDIREEFAELIEDALLANDEFFYVLSEESKEVAGSHRLEIKNDHRVKKAADELCRLLDKIGEALVFESEMYTIDQYELSVVEEYVEQMAYSLSLYQKDAISWLEKKEAESTFVVMPRTVAEVLGEKVFSKKIPYIFSSATLSEGGSFDYIADSLGIHDYLSLTVDSPYDYDEQMSINLYAKTDMDAEQKTAETIETIKRYKGRTLVLFPSFEELNEFKELSAAWELPYPIFFEGDEEISSLVEKFQEEEETVLCSVHLWEGLDIPGDALKNVTIWSLPFPPHDPVFTAKRNGAKKDPFEEVDLPYMLLRVRQGIGRLIRSNQDSGSIHIYAGGENERIIDEVKKVLPVEPHMM
What are the official names of this protein?
Probable ATP-dependent helicase YpvA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily.
Protein: RS4_SYNY3
Sequence: MSRYRGPRLRIVRRLGELPGLSRKSPRRAYPPGQHGQARRKRSEYAIRLEEKQKLRLNYGITEKQLVRYVKKARRATGSTGQALLELLEMRLDNTVFRLGMAGTIPGARQLVCHGHITVNGQVVDIPSYQCRPGDIVSVRDRDRSRKLVETNMEFPGLANVPSHLEFDKNTFTGKVNSVIDREWVALQINELLVIEYYSRKA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: BDP1_MOUSE
Sequence: MFRRARLSVKPNVRPGVGTRGSAAPNPQRGPEAPRPPEPATESAPKPAEPTDVPAVDSGGAEPQEQAPGSSDEKTGDKNNAAESSTLSSASSQRRKRVSSTSSLVQPSGSAPSQSRPLSTVDHDAPQPNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEKKQWKNKFSTNESQRPPDRSKMTMRDFIYYLPDNNPMTSSVEQEKKPEKSLAPTPTRDRQENQSTQDANDNEDVEEEVDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQSLKEKASKPRKNLKAKTVTSEEVNDDPDESVNSNISDPERSQNDAETVNEEESPSSSGQHLEQAMLEQDQNQEKKRRRNQGEANKQEATNLLERVLVHSSPPAAEIHKNTCPSEENESECNKEQIPSLTQNIDDIAGLAPSEETEMRMDPIPSTCNQQDIMPLARESSESCAVALPVWEPGNTASADMAHAESSCSEGRGADLKTAAPETEQTENVKPKSRSRLQRPKPNLARAVGKKSAVSQDRQDERNKNSPSETAAEKNHMEKETMNESETSVAKNTDGESPGAKTVSDLSEKSCVQQDSQAKVLRPTRLMRSRMQRPKPNVVKAAERKEILTSQEKFGAHVEKSEDESCVVIPPQTENESHKNLQCEDTVSEPGRKDPFENIQPDQPQVLSDCPSIHEGNKENKRKQVPVLRTRFQKPKPNTGRRRRRISSKEGIPEETPISGEIPATWEEIPSLDTSLREEVLSVPLAPLTATASTKDSESDVKDSGRNDTASNAEMSEMTDVTMEMETGLETIGRDTCPGEMGAEMIDIPMETEAGLKASLNETSCMEKVPELIDTTGEICTNLGETGRKEVFLQENGPKEVGPVSEPETGLQETGKDLAMKESTPDTTDSTEEREAYSEETERQEKISALIKDAEEAKARGEMETPLEEIGGGTSQRGKAAGAPVEQSASEEEPQGSACREEVAVESSTAEGKELNLRETGEDDVSSMVVVLGEKTDIEETNGDPKETERESSVSWERGSGEIQVGEEMVEDLGKPEKIDVAPREREPEEHSSGQPEADVILSSSDGSTGSPQDKVNISSKISVMPTLVEEKETTDKDISSHLGHVESCSQNLGRHETDQGMPLPDALERFSDTNLSKPLPQEQQPLQVKPAPFLRSRFKKPKPNLSRAALKRATIEAEHCVPGKKSEACKVEAAMLQQDSDQAALSPQHNVPSLMASRENDKSGHEEEEEAAILPCTQTEKDASPPNSSEPKEGSQLTPNQENGLLVPIGTPMMNTVTQETRQNVVQTTLPVRGRLQRPRPNVQKARQRQIVEKGEARDIAKNEGPELQKDETRTCLTVANSSHIESGVAVDMSSRVSECQVSESQGHADPVENLSVNKASVVHEQMRHENKPYVPSPALLIRRRFQKAKPNLGGARRKDEQPGVEKGRTDESTALTAEDHLLQKEDCDTQLSLQAREKADMPLEVSVRKECIHSEESGSDRNDAQPNAGPSEGSRDETAKEQPTSLGLEEQSLSKQIRSSCPQLWKESSYPKTVSSRRTPLSSASECEIEHSWKRTQRKTKPNLTKGRGSKRIRGKTAKKEPRASKSVLVTLRASQKEDEDDAEDFDSDYEEETYHLAPEELSKAPVFVPVGLRSPEPVSAQIEETMEELEITMDVADMTVVEHQLSHMDTTAQAVQAEKAVYPPSFEMDVGEQTQEEPGPSDGSTEAAITLLTMGDIVLQSEIIPGQGDVGVCVFPDVHSEDKSHAPFSPDNVNQKVVHDYPEVCSPVISTSHASFEENRIVSKEQSNRDAAVEEEAVEETLPTRNTTSTMSTHLRMESMVVTPELNSEKTLEISESHGHQEVASFCITKETEVEIQRETEGDDSKAVELEDKSHAPVTAAETKEEEQSQCVGDVEGASVSQEAILPARIEDHEETLQEVQESGTAVASSEIGQQTLDSGQSFGESAAKEALKETPKGSDVPVLHGPESVPSHIPEAQQENTGPQAVTVNPFADGQQDGEDEQAFILTLVEIPTHATEGFTDAAMQLMPSSLLPAPILVRSGNAAERGDLSGSLQTSLVVQDAPSLSPSRSGSSEKPPANLDLTSRKRFCCSPDESIHVPPAKKSSLVPGIDYQECTSEVCSEELNVFEKTAESCMGQGIFPTSESTHATSKPQKEHSEPTDTGSSGSLDEIKDACVENMAQLPQSEIVSDKEEKTEPASNSEQRDIVTSSSKPPLTRPGRRPLGFLSLLCPKNSLESDEVTQTHSKKRLKPQIPVSRRNLRKPNLHNTSQKKNQDSSAPPPSPSVTAPLSGTAGSPESSAAQVSSDQPLLKEECKNGPKGAPEEEVTPVSEFVFSDIFIEVDETL
What is the function of this protein?
General activator of RNA polymerase III transcription.  Requires for transcription from all three types of polymerase III promoters.  Requires for transcription of genes with internal promoter elements and with promoter elements upstream of the initiation site (By similarity).
What are the official names of this protein?
Transcription factor TFIIIB component B'' homolog, Transcription factor IIIB 150, TFIIIB150, Transcription factor-like nuclear regulator.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_DEHM1
Sequence: MAKRVYAIAMRYAQALYELAKEQKSLDKWQEDLQDLSSLTEDASVAEFLSNPKIASARKHKVLAKLSNIDPLMLNLVDMLVATRRLGIMRAVSGEYNRLLNEARGVEDAIVTTAKPSSEADIEIIRQQLSKITGKKINVVTATDPGLIAGLKARIGDKLIDGSVSRRLVLLQNEISQGRI
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: 3MGH_STRGG
Sequence: MTKSLDRTPLTRDFFDRDVLEVAPDLLGRTLVRREPAGTIELRLTEVEAYAGEVDPGSHAFRGRTARNSTMFGPPGHTYVYFTYGMWHCLNLVCGPDGHASGVLLRAGEIAVGAHLARDRRVSARNDKELAKGPARLATALDVDRALNGSDLFGGPAPALSVLHGTPPPRDLVRSGPRTGVGGDGAHQPWRFWIDGDPTVSPYRAHAPRRRPSRKAT
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.