PharMolix/UniProtQA huggingface dataset:
Protein: ICI_EISHO
Sequence: SPAVQEKAAWPELVGKTPEEARAQILLDKPNANVVVLEHHD
What is the function of this protein?
Inhibits chymotrypsin.
What are the official names of this protein?
Chymotrypsin inhibitor, EHCI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.
Protein: SYGA_BRUA4
Sequence: MHPTRSFQGLILTLHNYWAEHGCAILQPYDMEVGAGTFHPATTLRSLGPKPWKAAYVQPSRRPKDGRYGENPNRLQHYYQYQVIIKPSPPNLQDLYLGSLRAIGLDPTLHDVRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGIECSPVSGELTYGLERLAMYVQGVDNVYDLNFNGLEGDEKVTYGEVFLQAEQEYSRYNFEMANTEALRQHFIDAERECEAILKAGAPGPNANHQMHKSVFPAYDQCIKASHVFNLMDARGVISVTERQSYILRVRNLARQCGEAFLLTDAGGFNFKREGE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P55_GLRV3
Sequence: MDKYIYVTGILNPNEARDEVFSVVNKGYIGPGGRSFSNRGSKYTVVWENSAARISGFTSTSQSTIDAFAYFLLKGGLTTTLSNPINCENWVRSSKDLSAFFRTLIKGKIYASRSVDSNLPKKDRDDIMEASRRLSPSDAAFCRAVSVQVGKYVDVTQNLESTIVPLRVMEIKKRRGSAHVSLPKVVSAYVDFYTNLQELLSDEVTRARTDTVSAYATDSMAFLVKMLPLTAREQWLKDVLGYLLVRRRPANFSYDVRVAWVYDVIATLKLVIRLFFNKDTPGGIKDLKPCVPIESFDPFHELSSYFSRLSYEMTTGKGGKICPEIAEKLVRRLMEENYKLRLTPVMALIIILVYYSIYGTNATRIKRRPDFLNVRIKGRVEKVSLRGVEDRAFRISEKRGINAQRVLCRYYSDLTCLARRHYGIRRNNWKTLSYVDGTLAYDTADCITSKVRNTINTADHASIIHYIKTNENQVTGTTLPHQL
What are the official names of this protein?
Protein P55.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RS18_GLUDA
Sequence: MSETTEINPAARRTAVGARRPFYRRRKSCPFSGPNAPKIDYKDVRLLSRFLSERGKIVPSRITAVSAKKQRELAQAIKRARFMALLPYIVG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: P20D1_NEOFI
Sequence: MKPLSSLLLSAALSAAAPPHPASPQAPLADIPRIGVETRTEFSQNSLDDVVNASPLLSFHRDLVSIESISGNEGAAGAFVADFLESHNFTVIKQPVTTESDARFNIFAFPKSQSHSLDESHPSHGPQILLTSHIDTVPPFIPYSLHRDANDTDDRNILIAGRGTVDAKGSVAAQIFAALDTLAVQPPAPLGLLFVVGEETGGDGMKAFSQSTHLNPSPSRFHTVIFGEPTELALVAGHKGMLGFEVAAHGHAAHSGYPWLGESAISAILPALARVDHLGNIPVEEGGLPASDKYGRTTVNIGQMEGGVAANVVPSEARAGVAVRLAAGTHDEAREIVLKAVRDATGGDDRVVVNFSLEGYGPQDLDTDVAGFNVTTVNYGTDVPNLQLHPRPDGKVKRYLYGPGTIHVAHGDNEALTVAQLEEAVRGYKKLIQAALDRSTS
What are the official names of this protein?
Probable carboxypeptidase NFIA_052450, Peptidase M20 domain-containing protein NFIA_052450.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Secreted.
Protein: RTCA_PYRAB
Sequence: MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGTDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVATKYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWAETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGEIWVSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKVKVVRRVE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_TRIEI
Sequence: MTSQTCQLICPGLTKYSVAWEWQRSLVQQRHNCPELADVLILLEHPQVYTLGQGAKLDFLKFDPTQNKYELHRVERGGEVTYHCPGQLVGYPILNLKHYQQDLHWYLRQLEEVLIKVLDIFGLKGERYPGLTGVWLEGRKVGAIGIKVSRWITMHGFALNVSPNLEGFQRIVPCGISDKSVGSLAQFIPSITTDEVLPLVANAFAKVFGVKLVKSTNAILF
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_ECOLC
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQEIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP31_HUMAN
Sequence: MSKVTAPGSGPPAAASGKEKRSFSKRLFRSGRAGGGGAGGPGASGPAAPSSPSSPSSARSVGSFMSRVLKTLSTLSHLSSEGAAPDRGGLRSCFPPGPAAAPTPPPCPPPPASPAPPACAAEPVPGVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPSPDPEQPAGRGAQGQGEVTEQLAHLVRALWTLEYTPQHSRDFKTIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLNHSVKQSGQPPLKPPSETDMMPEGPSFPVCSTFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIPLPHTRPLYVTVVYQGKCSHCMRIGVAVPLSGTVARLREAVSMETKIPTDQIVLTEMYYDGFHRSFCDTDDLETVHESDCIFAFETPEIFRPEGILSQRGIHLNNNLNHLKFGLDYHRLSSPTQTAAKQGKMDSPTSRAGSDKIVLLVCNRACTGQQGKRFGLPFVLHLEKTIAWDLLQKEILEKMKYFLRPTVCIQVCPFSLRVVSVVGITYLLPQEEQPLCHPIVERALKSCGPGGTAHVKLVVEWDKETRDFLFVNTEDEYIPDAESVRLQRERHHQPQTCTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRRMKLQNMVKFPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNHHGTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFYQRRTAIPSWSANSSVAGSTSSSLCEHWVSRLPGSKPASVTSAASSRRTSLASLSESVEMTGERSEDDGGFSTRPFVRSVQRQSLSSRSSVTSPLAVNENCMRPSWSLSAKLQMRSNSPSRFSGDSPIHSSASTLEKIGEAADDKVSISCFGSLRNLSSSYQEPSDSHSRREHKAVGRAPLAVMEGVFKDESDTRRLNSSVVDTQSKHSAQGDRLPPLSGPFDNNNQIAYVDQSDSVDSSPVKEVKAPSHPGSLAKKPESTTKRSPSSKGTSEPEKSLRKGRPALASQESSLSSTSPSSPLPVKVSLKPSRSRSKADSSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPSPQKQKSASALTYTASSTSAKKASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRASATSTSKPNSPRVSQARAGEGRGAGKHVRSSSMASLRSPSTSIKSGLKRDSKSEDKGLSFFKSALRQKETRRSTDLGKTALLSKKAGGSSVKSVCKNTGDDEAERGHQPPASQQPNANTTGKEQLVTKDPASAKHSLLSARKSKSSQLDSGVPSSPGGRQSAEKSSKKLSSSMQTSARPSQKPQ
What is the function of this protein?
May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 31, Deubiquitinating enzyme 31, Ubiquitin thioesterase 31, Ubiquitin-specific-processing protease 31.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: SYL_CALS8
Sequence: MEYNFREIEKKWQQKWFSQNKYKVTEDSPKPKYYVLEMFPYPSGKLHMGHVRNYSIGDVFARFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIENMKRQLKELGISYDWDREVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVVNGRCERCKSLVGKKDLEQWFFRITKYAERLLRDIDKLDGWPEKVKIMQKNWIGRSEGAEIEFEIDGLGKRIKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQEKECLEFIEKMQYLNEIERTSTETEKEGRFTGGYAIHPLTGKKVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLPIKVVIKGDGVDIQNLQSAYEGEGVLINSGEFNGLKNTEAMKKITEYLEKNGYGKACVTYKLRDWLISRQRYWGAPIPIVYCDDCGIVPVPEEELPVLLPYNVEFKPTGQSPLAYCEEFVNTTCPKCGKPARRETDTMDTFICSSWYYFRYTDPKNSEKPFEKSLVDYWLPVDQYIGGVEHAILHLLYSRFFTKVLYDLGYISFEEPFKNLLTQGMVLKDGAKMSKSLGNIVSPEEIVEKYGADTARLFILFAAPPERDLEWSDQGVEGCFRFLNRLWRLYIELKDKLSDSSLPGQSELDDELNYRLNYTIKKVTEDIGERFNFNTAISSIMELLNFLYDYKEKGSLNRELILKTLKNFLILIYPFTPHIACELWEIMGFEGDIEDVSWPEYDESALVRKNVEIAVQINGKVRARFDVPVDISEEELKQKIMNNEKIKTLLEGKEIVKFIYVKNRLVNIVIK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_FRAT1
Sequence: MTWSDILAEEKQKPYFKQILDFLACESAKGKVIFPTKENIFNAFKYTELDNLKVVILGQDPYHNYNQAHGLAFSVQKGVDIPPSLQNIYKELARSIPEFKTPNHGYLVDWAKQGVFLLNTTLTVEAHKANSHKDIGWETFTDTVINKISENKHNVVFMLWGSHARKKKVLIDSSRHLILESTHPSPLSAHRGFLGCNHFVDCNKYLIEKKDQKIDWNLLC
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_SALHS
Sequence: MNIDLNADLGEGCASDSELLTLVSSANIACGFHAGDAQTMLTCVREALKNGVAIGAHPSFPDRDNLGRTAMVLPPETVYAQTLYQIGALGAIVQAQGGVMRHVKPHGMLYNQAAKDPRLAQAIAKAVHDYDPSLILVGLAGSELIRAGERHRLVTRQEVFADRGYQADGSLVPRTQPGALIHDEEQALAQTLDMVQAGRVKSVTGVWTTVTAQTVCIHGDGEYALAFARRLRAAFNARNIHVIA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: ISPD_PETMO
Sequence: MVYAIIVAAGEGKRAGFEIPKQFVKLNNKTILRMSAEKFQNSASIDKFLVVSHRNYVDLTEKEVKIFSKFENVVIGGSNRQESVYNALMYLGKKENKPDFVCIHDAVRPFVDTNKIDESIYKAKEIGGAVLAEMAENTISQVNNGRIVKTLERSQIYLHHTPQTFDFNKLLKAYQKAEKILSSFTDDASIFIHAGYETAIVEDYKNNIKLTKKEDFELAKCIFELNS
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: MSD3_XENTR
Sequence: MQNNEILKPAKYFSELEKSVLLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKGKLFGPESNSHQALKEKVASMIPEQLYFVQNQPDDERGYNHDTSNQEMDCKRVSLLDLEVLIDEQGKIQTKPFRKVPETNSLCDDGSPPQSIDKAFPNGDLELLIDEQGKIQAEPIRKVPVTDSQCAQGSPSSSIKTESFVVPERDVYEDQNSIVNMHSSESSLHSTPLFPSSKISANRTYGRKPSQNGIFTKMHEEQHHQQMSILQLQLIQMNEVHVAKVQQIERECEMAEEEHRIKMEILNKKKMYWERKLQTITKEWPVASFNRPFPNSP
What are the official names of this protein?
Myb/SANT-like DNA-binding domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the MSANTD3 family.
Protein: HFE_RHIUN
Sequence: MGPRARPALFFLILLRTVAAQGRPPRSHSLRYLFMGASERDHGLPLFEALGYVDDELFVAYNHESRRAESRAQWVLGEAHSQLWLQLSQSLKGWDHMFIVDFWTIMDNHNHSKESHTLQVILGCEVQEDNSTRGFWMYGYDGQDHLEFCPETLDWRAAESRALTTKLEWEVNKIRAKQNRAYLERDCPEQLQWLLELGRGVLDQQVPPLVKVTHHVASAVTTLRCQALNFYPQNITMRWLKDRKPVDVKDAESKDVLPSGDGTYQSWVALAVPPGEEQRYTCQVEHPGLDQPLTATWEPSLSNTLVTGVISGIAVCVIIFLIGILFRILRKRQASRGAMGDYVLAECE
What is the function of this protein?
Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
What are the official names of this protein?
Hereditary hemochromatosis protein homolog.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RSMH_ACAM1
Sequence: MTPDPGAFNHISVLSHELMAGLMLQEQGLYLDATVGGGGHSALILSQYPQTQVIALDQDIQALEAARAKLHDACDRIQFWQGNFSTYHPGELRFDGIIADLGVSSAQLDRPERGFSFRYDADLDMRMDQSQGLTAADVINTYSERDLADIFYHYGEERFSRRIARKIVSKRPLRTTSDLARVVASSLPAAKGRRRRIHPATRVFQALRIAVNQELQVLEKFIEIAPTWLKPGGRIGIISFHSLEDRIVKIHFRQNSLLQVVTKKPIVASEQEKRENSRSRSAKLRFAERVPLADEAES
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_STAAM
Sequence: MKCPKCNSTQSKVVDSRHADELNAIRRRRECENCGTRFTTFEHIEVSQLIVVKKDGTREQFSREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTEVSSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILSENKRSDA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: Y3985_DICDI
Sequence: MEITYILSKYFGSSRSNIYQSNSQQSLTIQNSNVASKKLNVYEFIPYY
What are the official names of this protein?
Putative uncharacterized protein DDB_G0291564.
Protein: IMDH_MYCTO
Sequence: MSRGMSGLEDSSDLVVSPYVRMGGLTTDPVPTGGDDPHKVAMLGLTFDDVLLLPAASDVVPATADTSSQLTKKIRLKVPLVSSAMDTVTESRMAIAMARAGGMGVLHRNLPVAEQAGQVEMVKRSEAGMVTDPVTCRPDNTLAQVDALCARFRISGLPVVDDDGALVGIITNRDMRFEVDQSKQVAEVMTKAPLITAQEGVSASAALGLLRRNKIEKLPVVDGRGRLTGLITVKDFVKTEQHPLATKDSDGRLLVGAAVGVGGDAWVRAMMLVDAGVDVLVVDTAHAHNRLVLDMVGKLKSEVGDRVEVVGGNVATRSAAAALVDAGADAVKVGVGPGSICTTRVVAGVGAPQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAEAPGELIFVNGKQYKSYRGMGSLGAMRGRGGATSYSKDRYFADDALSEDKLVPEGIEGRVPFRGPLSSVIHQLTGGLRAAMGYTGSPTIEVLQQAQFVRITPAGLKESHPHDVAMTVEAPNYYAR
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: TGT_LEPBJ
Sequence: MIFQTTSEDLRTRARTGILNLNGVKLETPVFMPVGTRGVVKTISADDLEELEYSLILGNTYHLYLRPGTAVLERFGGLKKFSTWKRALLTDSGGYQVFSLNSLFKYEQDGVRFQSHIDGSRHYFTPNSVIDIQRTIGSDIMMVLDDCAPFDSSQERLRQSLDRTHRWAEMSVEYWEKNKNSSHLFGIFQGGIDLGLRLESLQKIVSLPFDGIAIGGLSVGEPRKDFIRILEGVSAYTDRSRPLYLMGVGTVPDILDGVKNGVDMFDCVLPTRNARNGQVFTSLGKINLRNEKWKSSDVPIDPHCGCKVCKRYSIGYIRHLHHVGELTAFSLSTYHNLYFMKNFLSEIRKSIQAGEFLKIYAKWKNLYEKPEFSG
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DYN3_CANGA
Sequence: MLRRALEEKYALKIGEIRTTTAVICSISTDTILDFEKQCLKPHCTFSKPIINLGYTYYDIPSEYKEELNESIAVNHRIDAYALITTFDETPIESIEPLISNDKSEIKWTFLLDWTELHQGTWLRFLSKQFESLESKGYDLKNENISVWCMNSDYMFELQKNDILWESFHFEYLQQSLRSVLFYRNGSLIYVDKKRNQLPLFEIFVKLCLHNRNDKYKSLNQFTEMSETSQVFIPFNSDSEDLIKTIDEEFQPEEVLKPDFMPTFEKVIPYSKPKDEPHLPPIGELPHFDMNKELEEAAIILKQASKKEAYAKQNI
What is the function of this protein?
Component of the cytoplasmic dynein which acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast.  Probably required for normal progression of the cell cycle (By similarity).
What are the official names of this protein?
Cytoplasmic dynein intermediate light chain DYN3, Dynein protein 3.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain DYN3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ISPF_CHLCV
Sequence: MDAENDSPLPKPQWIYRVGIGQDSHRFLSESSAKPCILAGVIFENSPGFQANSDGDIVFHAICNAISSVTHRIILGEVADELFHTRGITDSSVYLSEAIKSLKSNQMISHVAITIEGNRPKFLPKLSAMRQSIASALNIPLGSVGITATSGEGLSDFGCGDGVQCFCVLTVAEYCN
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SYM_SHIFL
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPELYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKATTAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP3_EUGST
Sequence: MSSFILKFLWLEKSVAVGLDQKIGDRTTPVTEFFFWPQHDAWEEMKNFLEDKSWIDQSEVVILLNQITEVINYWQEKTELQKRDISHLTEKFPNVVFVGFD
What is the function of this protein?
Probably a ribosomal protein or a ribosome-associated protein.
What are the official names of this protein?
Probable 30S ribosomal protein 3, chloroplastic, PSRP-3.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cS23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNTH_MYCTU
Sequence: MAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAIAYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLVTGRSLPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNLPLPIGGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFFVVTPPPNAVLGGLAPRFQGTESVLLAAAIMGATVMPHAVYLHSGLARDRHGHPDPGPQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGRGDTASIEGAYHAVHDTLGATIAVLFAVGLLASGLASSSVGAYAGAMIMQGLLHWSVPMLVRRLITLGPALAILTLGFDPTRTLVLSQVVLSFGIPFAVLPLVKLTGSPAVMGGDTNHRATTWVGWVVAVMVSLLNVMLIYLTVTG
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.  Transports zinc and iron.  Can also interact with manganese and copper.
What are the official names of this protein?
Divalent metal cation transporter MntH, Mramp.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL6_SINMW
Sequence: MSRIGKKPVQVPAGVTANVDGQKVTAKGPKGELFFVANDEVSVKLENNTVVVQPVNESKDARAKWGMSRTMIENILKGVKDGYERKLEINGVGYRASMQGKNLQLALGFSHDVVYQTPEGITIAVPKPTEIVVSGINKQQVGQVAAEIREYRGPEPYKGKGVKYAEERIVRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ETF1_MONPV
Sequence: MNTGIIDLFDNHVDSIPTILPHQLATLDYLVRTIIDENRSVLLFHIMGSGKTIIALLFALVASRFKKVYILVPNINILKIFNYNMGVAMNLFNDEFIAENIFIHSTTSFYSLNYNDNVINYNGLSRYNNSIFIVDEAHNIFGNNTGELMTVIKNKNKIPFLLLSGSPITNTPNTLGHIIDLMSEETIDFGEIISRGKKVIQTLLNERGVNVLKDLLKGRISYYEMPDKDLPTIRYHGRKFLDTRVVYCHMSKLQEKDYMITRRQLCYHEMFDKNMYNVSMAVLGQLNLMNNLDTLFQEQDKELYPNLKINNGVLYGEELVTLNISSKFKYFINRIQTLKGKHFIYFSNSTYGGLVIKYIMLSNGYSEYNGSQGTNPHMINGKPKTFAIVTSKMKSSLEDLLDVYNSPENDDGNQLMFLFSSNIMSESYTLKEVRHIWFMTIPDTFSQYNQILGRSIRKFSYVDISEPVNVYLLAAVYSDFNDEVTSLNDYTQDELINVLPFDIKKLLYLKFKTKETNRIYSILQEMSETYSLPPHPSIVKVLLGELVRQFFYNNSRIKYNDSKLLKMVTSVIKNKEDARNYIDDIVNGHFFVSNKVFDKSLLYKYKNDIITVPFRLSYEPFVWGVNFRKEYNVVSSP
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa RAP94/OPG109 to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters.
What are the official names of this protein?
Early transcription factor 70 kDa subunit, ATP-dependent helicase VETFS, ETF small subunit, VETF D6 subunit, Vaccinia virus early transcription factor small subunit, VETF small subunit.
What is the protein family that this protein belongs to?
Belongs to the helicase family. VETF subfamily.
Protein: CYB_DOLPA
Sequence: MTHMRKSHPLIKIINHSFIDLPTPSNISAWWNFGSLLGICLGLQIITGLFLAMHYTADTITAFSSVTHICRDVNYGWLIRYLHANGASMFFILLYLHIGRGIYYGSYTFMETWNIGILLLFAVMATAFMGYVLPWGQMSSWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIPALVMIHFFFLHETGSNNPSGLNSDSDKIPFHPYYTIKDIMGLLIMMLALMSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLALFPMLHLSKQRSMTFRPFSQCLLWMLTANLFILTWIGGQPVEYPYITIGQLASINYFFTILIVSRLVSLMENKVLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RBFA_ECOK1
Sequence: MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.