PharMolix/UniProtQA huggingface dataset:
Protein: HIS6_THEFY
Sequence: MSLAVRVIPCLDVDGGRVVKGVNFQNLRDAGDPVELARRYDAEGADELTFLDVTASSSNRETTYDVVRRTAEQVFIPLTVGGGVRSTEDVDRLLRAGADKVSINTAAVRRPELIREIAQEFGSQVLVLSADVRRTVNGTATPSGFEITTHGGRQGTGIDAVEWVQQAEELGAGEILLNSMDADGTKSGFDLELIRAVRKAVNVPLIASGGAGAVEHFAPAVDAGANAVLAASVFHFGEITISDVKAELRAKGYPVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF141_ARATH
Sequence: MTKSIISAFFIILILGMMVNEIEGQQQQQRCEEALTEIDCGAGNCNALCLQKRKGLGRCVQRTPCDKLKCMCYYPCSS
What are the official names of this protein?
Defensin-like protein 141, Low-molecular-weight cysteine-rich protein 3, Protein LCR3.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_PSEF5
Sequence: MAVQRTFSIIKPDAVAKNVIGKIVSRFEEAGLRVVASKMKQLSKAEAEGFYAEHSERGFFGELVAFMTSGPVVVQVLEGENAIVRNRELMGATNPKEAAAGTIRADFAESIDANAVHGSDSEAAAAREIAYFFAATEVTAR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y323_METJA
Sequence: MFLALTSIAIPAAIVIPISLIANLPNCGISLTFSMTIGFVGLILTIAASPVFKNCGFSSMTCPVLGSNFFNNSMNVHATCAVCAWKTGV
What are the official names of this protein?
Uncharacterized protein MJ0323.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MYB27_ARATH
Sequence: MDFKKEETLRRGPWLEEEDERLVKVISLLGERRWDSLAIVSGLKRSGKSCRLRWMNYLNPTLKRGPMSQEEERIIFQLHALWGNKWSKIARRLPGRTDNEIKNYWRTHYRKKQEAQNYGKLFEWRGNTGEELLHKYKETEITRTKTTSQEHGFVEVVSMESGKEANGGVGGRESFGVMKSPYENRISDWISEISTDQSEANLSEDHSSNSCSENNINIGTWWFQETRDFEEFSCSLWS
What are the official names of this protein?
Transcription factor MYB27, Myb-related protein 27, AtMYB27.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRP19_BOVIN
Sequence: MACAAARSPADQDRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCAAVGLNVFLEKNKMYSREWNRDLQYRGRVRVQLKQEDGSLCLVQFPSRKSVMLYAAEMIPKLKTRTQKTGGGDQSLQQGEGSKKGKGKKKK
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  Binds directly to 7SL RNA (By similarity).  Mediates binding of SRP54 to the SRP complex (By similarity).
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Although the signal recognition particle complex acts in the cytoplasm, it assembles at least in part in the nucleus and/or the nucleolus. SRP19 nuclear import may be mediated by IPO8/Imp8 and TPNO1/Trn.
Protein: RNZ_STAAW
Sequence: MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGVPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKV
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: BUK_BACC1
Sequence: MSLNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPVARISGIAGMERKSIFHALNQKAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMVKKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_FLAPJ
Sequence: MGVRKRETADARKEANKSIAFAKLNNCPTSPRKMRLVADLVRGQKVDRALNILRFSSKEASRKLEKLVLSVIANWQAKNPEANMEEAGLFIKTITVDGGMMLKRLRPAPQGRAHRIRKRSNHVTIVLGSINNTQAIN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ORCKB_PROCL
Sequence: MTAQMFTIALLLSLSAIAAAGTIKTAPARTPSTQDDASFPPDGAPVKRFDAFTTGFGHSKRNFDEIDRSGFGFAKKNFDEIDRSGFGFNKRNFDEIDRSGFGFNKRNFDEIDRSGFGFNKRNFDEIDRSGFGFNKRNFDEIDRSGFGFNKRNFDEIDRSGFGFNKRNFDEIDRSGFGFNKRNFDEIDRSGFGFVKRVYVPRYIANLYKRNFDEIDRSGFGFNKRNFDEIDRTGFGFHKRDYDVFPDKRNFDEIDRSGFGFVRRNVE
What is the function of this protein?
Myotropic peptides that enhance both the frequency and amplitude of spontaneous hindgut contractions.
What are the official names of this protein?
Orcokinin peptides type B.
What is the protein family that this protein belongs to?
Belongs to the orcokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAA_SACHY
Sequence: MIIRPSEPEVKIAVDRDPVKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTGDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALIFASLMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQIHVSLPINQFLDAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYAEFLSFRGGLDPITGGLWLSDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSTTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWIQNIHAGAPGVTAPGATTSTSLTWGGGELVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGTISDQGIVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MURQ_SHIB3
Sequence: MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNINLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGISCNPGSAVSTTAEFAITPIVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: HIS5_BACC0
Sequence: MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGVSDYGVEVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TR109_MOUSE
Sequence: MEHLLKRTFDITENILLIILFIELIIGLIGNGFTALVHCMDWVKRKKMSLVNKILTALATSRIFLLWFMLVGFPISSLYPYLVTTRLMIQFTSTLWTIANHISVWFATCLSVFYFLKIANFSNSPFLYLKRRVEKVVSVTLLVSLVLLFLNILLLNLEINMCINEYHQINISYIFISYYHLSCQIQVLGSHIIFLSVPVVLSLSTFLLLIFSLWTLHKRMQQHVQGGRDARTTAHFKALQAVIAFLLLYSIFILSLLLQFWIHGLRKKPPFIAFCQVVDTAFPSFHSYVLILRDRKLRHASLSVLSWLKCRPNYVK
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 109, T2R109, mT2R62.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACOHC_CUCMA
Sequence: MAAENPFKENLTSLPKPGGGEFGKYYSLPSLNDPRIDRLPYSIRILLESAIRNCDNFQVKKEDVEKIIDWENSSPKQVEIPFKPARVLLQDFTGVPAVVDLACMRDAMNKLGSDSNKINPLVPVDLVIDHSVQVDVARSENAVQANMELEFQRNKERFAFLKWGSNAFQNMLVVPPGSGIVHQVNLEYLGRVVFNTSGLLYPDSVVGTDSHTTMIDGLGVAGWGVGGIEAEAAMLGQPMSMVLPGVVGFKLSGKLRNGVTATDLVLTVTQMLRKHGVVGKFVEFYGDGMEELSLADRATIANMSPEYGATMGFFPVDHVTLQYLKLTGRSDETVSMIEAYLRANKMFVDYKEPQQEKVYSSYLQLDLTDVEPCISGPKRPHDRVPLKEMKSDWHACLDNKVGFKGFAIPKEAQENVAKFSFHGQPAELKHGSVVIAAITSCTNTSNPSVMLGAALVAKKACELGLQVKPWVKTSLAPGSGVVTKYLLKSGLQPYLNQQGFHIVGYGCTTCIGNSGDLDESVSAAISDNDIVAAAVLSGNRNFEGRVHPLTRANYLASPPLVVAYALAGTVDIDFEKEPIGKGKDGKDVYFRDIWPSTEEIAEVVQSSVLPDMFKSTYESITKGNPMWNQLSVPSGTLYSWDPNSTYIHEPPYFKNMTMDPPGAHGVKDAYCLLNFGDSITTDHISPAGSIHKDSPAAKYLLERGVDRKDFNSYGSRRGNDEVMARGTFANIRLVNKLLDGEVGPKTVHVPTGEKLSVFEAAEKYKSAGQDTIVLAGAEYGSGSSRDWAAKGPMLLGVKAVIAKSFERIHRSNLVGMGIIPLCFKSGEDADSLGLTGHERYTIDLPDDISKIRPGQDVTVTTDSGKSFTCTVRFDTEVELAYFNNGGILPYVIRNLIKQ
What is the function of this protein?
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
What are the official names of this protein?
Aconitate hydratase, cytoplasmic, Aconitase, Citrate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGB1_CAEEL
Sequence: MEVDLPVHNEYDASRFHQVTIRDPIAGADSTFTIPTRYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLRLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILGLPYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSAAMYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVEDALNHPYVKLWFKDDEVNAPASENRYDQEIDFADKTLIEWKELIFNEVQRYQADHDIFTG
What is the function of this protein?
Mitogen-activated protein kinase which is an essential component of the JNK pathway composed of mlk-1, mek-1 and kgb-1 (PubMed:15116070, PubMed:22554143, PubMed:23352664).  Phosphorylates the transcription factor fos-1 which prevents fos-1 dimerization and promoter binding and results in activation of target genes including F53A9. 2/kreg-1 and lys-3/kreg-2 (PubMed:23437011).  Phosphorylates jun-1 and activates the AP-1 transcription factor which is a heterodimer of jun-1 and fos-1 (PubMed:23352664).  Phosphorylates glh-1 in vitro which may play a role in controlling glh-1 protein levels in the germline by targeting it for degradation by the proteasome (PubMed:17699606).  Required for oogenesis and probably also for spermatogenesis (PubMed:12435362).  Involved in the response to environmental stress such as heavy metals, infection and protein folding stress in an age-dependent manner (PubMed:15116070, PubMed:22554143).  In larvae, has a protective role which becomes detrimental in adults (PubMed:22554143).  May control susceptibility to infection, heavy metal stress and premature lethality by regulating daf-16 cellular localization (PubMed:22554143).  Involved in the transcriptional response to bacterial pore-forming toxins and to fasting (PubMed:15256590, PubMed:21408619, PubMed:23352664).  Required for fasting-induced longevity (PubMed:23352664).  Involved in axon regeneration after injury downstream of tyrosine receptor svh-2 (PubMed:21670305, PubMed:22388962).
What are the official names of this protein?
GLH-binding kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Uniformly cytoplasmic in distal germline but resolves into discrete particles in developing oocytes.
Protein: SYP_CORDI
Sequence: MITRLSTLFLRTLREDPADAEVPSHKLLVRAGYIRRTAPGVYTWLPLGLRTLRKVETVVREEMDAIGAQELLFPALLPREPYEQTHRWTEYGDSLFRLKDRKGGDYLLGPTHEEMFASAVKDMYSSYKDFPVTLYQIQTKYRDEERPRAGILRGREFVMKDSYSFDMSDAGLEDSYQRHREAYQRILDRLGVEYVICAATSGAMGGSASEEFLAVSDNGEDTFVRATEGPYAANVEAVVTQPGVERPLEQAPEAVEYETPNAETIEALVQWAQSAGVTVEDRSVAAADTLKCLLVKITQPGAEEAELAGILLPGDREVDMKRLEASVEPAEVELASEEDFKNNPFLVKGYVGPRALNAHGVKVLADPRVVSGTSWIAGADAVEHHVVGLTMGRDFTVDGYIEAAEIREGDPAPEGQGTLTLARGIEVGHIFQLGRKYTEAFDVQILDESGKRAIPTMGSYGIGVSRLMAVLAEQRHDETGLNWPLEVAPYQVHVVVANKDKEAIEAGDALVAALDSHGIEVLFDDRPKVSPGVKFKDAELLGMPFVVVLGRAFKDGNIELRERGQETVLVSADEIVDTVVAKLNR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRK22_ARATH
Sequence: MKQRSFLSILCFILLAFGVASVSAQTCIENRKYFTPNGTYDSNRRLILSSLPNNTASQDGFYYGSIGEEQDRVYALGMCIPRSTPSDCFNCIKGAAGWLIQDCVNQTDAYYWALDPTLCLVRYSNISFSGSAAFWEIEPQYLVLNTATIASDLTDFKNIWEDLTSRTITAASAARSTPSSSDNHYRVDFANLTKFQNIYALMQCTPDISSDECNNCLQRGVLEYQSCCGNNTGGYVMRPICFFRWQLFTFSKAFHNITLATPPKPPMNVPRPPSVGHGANTTDNDSRGVSAGIVVVITVPAVVIVLILVVLGFFICWRRKSLQRTEFESDSDVSTTNSLQYEFKTIEAATNKFSKSNKLGEGRFGEVYKGKFSNGTEVAVKRLSKVSGQDTKKFRNEAVLVSKIQHRNLARLLGFCLQGDGKFLIYEFVLNKSLDYFLFDPEKQGELDWTRRYKIIGGIAQGILHLHQDPQLTIIYRDFKASNILLDADMNPKISDFGMATVFGMEESRGNTNWIAETFVYMSPEYAVHGKFSMKSDVYSFGILILEIISGKKNSSLYQNDETTTAGNLVTYAWRLWRNGSQLKLLDSSIGRNYQSNEVTRCIHIALLCVQENPEDRPKLSTIVSMLTSNTISVPAPGIPGFFPQSRRELDPLSEGLESG
What are the official names of this protein?
Cysteine-rich receptor-like protein kinase 22, Cysteine-rich RLK22.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SMALL_TMEVD
Sequence: MDTQMCALFAQPLTLLPDLNICSWQTVNGSQRTFFVWTWTMTSSGLRTRAINLKQWNGLTYRSYAILSWNPRETPLHLTRVTPSPQVTKGSLSTTSIPINTKIQLICLPAVAMLATPPKTTDNCRTSWAALQMLLLLWHLSSWIKTQRRWRISLTE
What is the function of this protein?
May be required for viral persistance in the host.
What are the official names of this protein?
Protein L*.
Protein: CPFC_CORDI
Sequence: MLPLPTWTLSDVDAILVLSFGGPEGQQDVIPFLENVTRGRGIPRERLEEVAVHYRHFGGISPLNALNREIIGNIIEVLSSRGLEIPVYFGNRNWHPFVNDTAEKMVRDGVRNVAVFATSAWGGYSGCRQYDEDIVRMNHHLEEKELPTLNCLKLRQFFDHPLFIEEMSSVVFQAARELGISALDELQLHQKVVFTAHSIPEVANENSGRKEDGPLYSRQVYEAASLVAKHLGISQERYDVVWQSASGNGQIPWLEPDILDYAKCQHDEGVSELVVAPIGFISDHMEVVWDLDHELQDLASDLGMSISRAATVGHTDSFATMIVELVEESLGVKPHQNLGTVPSKGCSFNGEPCEVNCCKPVQRPHSAKA
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_PSEP1
Sequence: MRERLLAAEKVTAIRWQGGALHLLDQRLLPSEERWLACDNVAQVAAAIRDMAVRGASAIGIAAAYGLVLALEERLAEGGDWEMDLEDDFLTLAEARPTAANLFWALNRMRERLLRLRPEEDVLAALEAEAVAIHESDREANLTMAQQGIELIRRHQGNAQALLTFGNAGALASGGFGTALGVIRAGYLEGMVERVYAGETRPWLQGSRLTAWELANEGIPVTLCADSALAHLMKTKGITWVVVGADCIAANGDVASKIGTYQLAVSAMHHGVRFMVVAPSTSIDLNLATGEDIPLEERDADEWLDFGGAPAVRDVQVFNPVFDVTPADLIDVIVTERGVVERPDTAKLAQLICRKRLH
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: LCAT_MICMN
Sequence: FFTIWLDINMFLPLGVDCWIDNTRVVYNRSSGRMSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYLHTLVQNLVNNAYVRDETVRAAPYDWRLAPSQQDEYYQKLAELVEEMYDAYGKPVFLIGHRLGCLHVLHFLLHQSWKGIPIMSNIKLKEEQRITTTSPWMFPAHHVWPEDHVFISTPNFNYTGQDFKRFFADLHFEEGWYMFLQSRDLLEGLPAPGVEVYCLYGVGRPTRYTYIYDHNFPYKDPVAILYEDGDETVATRSTELCGQWQGRQSQPVYLLPMNGTDHLNMVFSNKTL
What is the function of this protein?
Central enzyme in the extracellular metabolism of plasma lipoproteins.  Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs).  The cholesterol ester is then transported back to the liver.  Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines.  Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels.  Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins.  Required for remodeling high-density lipoprotein particles into their spherical forms (By similarity).
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma. Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (By similarity).
Protein: LAP4A_CHICK
Sequence: MTFKRSRDRFYSTRCCGCCHVRTGTIILGTWYMVVNLLMGILLTVEVTHPNVVPTVNIQYEVIGNYYASERMAENACVLFAISLLMFTISAMMVYGAIAHRVGWLIPFFCYQLFDFVVSCLVAISSLTYLPRIKDYLDQLPDFPYKDDLLSLDSSCLLFIVLVFFALFIILKAYLINCVWNCYKYISNRNLPEIAVYPAFEAPPQYVLPTYEMAVKMPEKEPSPSYIPA
What is the function of this protein?
May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.
What are the official names of this protein?
Lysosomal-associated transmembrane protein 4A.
What is the protein family that this protein belongs to?
Belongs to the LAPTM4/LAPTM5 transporter family.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Note=May reside in an intracellular membrane-bound compartment.
Protein: RF1_LEGPL
Sequence: MKKSLELKLQQMLERYEEVGRLLSEASIIADQNQFKSLSKEYAQLEPVSQCYESYLEAKNNLDSLNELLESDDKDLATMAEEEIDTVKKQIEELDEQLQWHLIPKDPDDERNIYLEVRAGTGGDEAAIFAGDLFRMYSRYAESQGWQIELISASHGEHGGYKEIIAKISGQAVYSQLKFESGAHRVQRVPETESQGRVHTSACTVAIMPEVDEINDIQINPDDLRIDTYRSSGAGGQHVNKTDSAIRITHIPTGVVVECQDERSQHKNRAKAMSLLKTRLLDAEVSKQKQEQAQTRKSLVGTGDRSERIRTYNFPQGRLTDHRINLTIYQLSDIMEGNLSLVIDPLKREYHAELLADLGRHD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCB_PSEPF
Sequence: MGIPCHFALFELQPGFRLDLEQLATRYRELARGVHPDRFADASEREQRSALEQSARLNDAYQTLKSPAQRARYLLTISGHEVPMEVTVHDPEFLLQQMQWREELEDLQDSADLAGVAAFKRRLKTAQEELNESFAACWDDAAQREQAERLMRRMQFLDKLTYEVRQLEERLDD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: GST29_FASHE
Sequence: MPAKLGYWKIRGLQQPVRLLLEYGEKYEEQIYERDDGEKWFSKKFELGLDLPNLPYYIDDKCKLTQSLAILRYIADKHGMIGSTPEERARVSMIEGAAVDLRQGLSRISYDPKFEQLKEGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPNLQQFMSRIEALPSIKAYMESNRFIKWPLNGWHAQFGGGDAPPSHEKK
What is the function of this protein?
GST isoenzymes appear to play a central role in the parasite detoxification system.  Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
What are the official names of this protein?
Glutathione S-transferase class-mu 26 kDa isozyme 1, GST1, Fh1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
Protein: LBHD1_HUMAN
Sequence: MALVPGRSKEDGLWTRNSPGSSQHPESPRLPNPLWDRGKIGKVEGHQHIQVSTSSACVWQLAYPPVWPNLPAVPIQDFSQKSHLPSIVVESSEVNEESGDLHLPHEELLLLTDGEEEDAEAFFQDQSEEPGWAWSPQDPRSPLRTFNAGLSWGQDQDEEDACWILEDTACLEATNHCPFWDSTGSRVCRSGFVEYSHLLPPNSFEGAEEEAVQTPAGVESGAASEAPGGRGCDRPRADHAAPPQEAGVQCTCQHYTVREEAQKTPPADPACPEREDSHGSGSPFKASQD
What are the official names of this protein?
LBH domain-containing protein 1.