PharMolix/UniProtQA huggingface dataset:
Protein: LIP2_STAA8
Sequence: MLRGQEERKYSIRKYSIGVVSVLAATMFVVSSHEAQASEKTSTNAAAQKETLNQPGEQGNAITSHQMQSGKQLDDMHKENGKSGTVTEGKDTLQSSKHQSTQNSKTIRTQNDNQVKQDSERQGSKQSHQNNATNNTERQNDQVQNTHHAERNGSQSTTSQSNDVDKSQPSIPAQKVIPNHDKAAPTSTTPPSNDKTAPKSTKAQDATTDKHPNQQDTHQPAHQIIDAKQDDTVRQSEQKPQVGDLSKHIDGQNSPEKPTDKNTDNKQLIKDALQAPKTRSTTNAAADAKKVRPLKANQVQPLNKYPVVFVHGFLGLVGDNAPALYPNYWGGNKFKVIEELRKQGYNVHQASVSAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYKGIMPNWEPGKKVHLVGHSMGGQTIRLMEEFLRNGNKEEIAYHKAHGGEISPLFTGGHNNMVASITTLATPHNGSQAADKFGNTEAVRKIMFALNRFMGNKYSNIDLGLTQWGFKQLPNESYIDYIKRVSKSKIWTSDDNAAYDLTLDGSAKLNNMTSMNPNITYTTYTGVSSHTGPLGYENPDLGTFFLMATTSRIIGHDAREEWRKNDGVVPVISSLHPSNQPFVNVTNDEPATRRGIWQVKPIIQGWDHVDFIGVDFLDFKRKGAELANFYTGIINDLLRVEATESKGTQLKAS
What are the official names of this protein?
Lipase 2, Glycerol ester hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1610_BACAA
Sequence: MNTPVSVNEKKDFVKWFLNNYQLKQRECVWILNYLMSHDQLMHKVHFVEHAKYCPRGLVMSANCVKDTPFHFFKQNVMTTDAEKSFHDIRLNRDEDIYIQLNFKSSFQNANYVAVLEENPYLPKHIEVNEKDRLLAERFLEESVFSFRRERLLKQIDEALDKQDKEAFHRLTAELKML
What are the official names of this protein?
UPF0302 protein BAA_1610.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: SEQA_SHEFN
Sequence: MKYIEIDEELYRFIASKTERIGESASDILRRLLNLSVENVDVSLPTDISHPSLESQSPVNRHPVFDQAKAAVEKVIADQNSANEHYPVDEDIASSTSIDFDAMVSQHLLSQQKGAVGRFMYLLSSLESTAGSDFDKVLNVQGKGRLYFARSKQALLNSSKSSNPKEIASSGFWVTTNNNTAKKQTILTEVLEHLGCDSERAKSIAEHI
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAT1_SCHPO
Sequence: MSAVDEWVHNANECIEIVQVNEKHEKDCQYHPSNTYAIFGDAEVIYGYKDLNVTITYECPLMVPKLEISYSERLAPDSGVEPTDIEGTLNTYLKDRSIKVEGNSFDVHSANSIHNYSFNGKTFKILQATVLEASEIMQHLQIFSLFFIEGGSFIDLNDPRWMVYLLYETTEDDYCLRGYCTVYKYYKWDKLIHDGIRARISQFVILPPFQHQGHGSQLYNAIVSTFLKNPKILDFTVEDASEAFDSLRDHCDYKRLLSMGIFSEPDFHPSLSRQWINSKIAETKLTQRQFSRCCELAFTTKLKKLSLLERKSVRLGIKERIFRQNLDVLLQLDKSERIEKIHNAYENQFDEYKQIVKKLPKLKEDSPRKRQKLAQSSS
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.  Involved in DNA double-strand break repair.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CO4A2_BOVIN
Sequence: ISIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIPEQSFQGTPSADTLKAGLIRTHISRCQVCMKNL
What is the function of this protein?
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.  Potently inhibits angiogenesis and tumor growth (By similarity).
What are the official names of this protein?
Collagen alpha-2(IV) chain.
What is the protein family that this protein belongs to?
Belongs to the type IV collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: QUEF_CAMJR
Sequence: MRYGEKEIKEFDVENMEIWPNDAKNDYIIKITLPEFMCCCPRSGYPDFATIYLEYMPNKFVVELKAIKLYINTFMYRNVSHEASINEIYNTLKDKLKPKWIKVVGDFNPRGNVHTVIECRSDMVVPK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_ECOL5
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_ERYLH
Sequence: MARIAGVNIPTNKRVIIALTYIHGIGRTTAVKIADKLGIDHARRVQDLTDEEVLRLRETIDEDLMVEGDLRRETAMNIKRLMDLKSYRGLRHRNGLPVRGQRTHTNARTRKGKAKPIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RS10_STAS1
Sequence: MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTERSVYTVIRAVHKYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: VWKA_DICDI
Sequence: MESKYVLSTEKESKTKPSGRVNVSDMDSISNSLSKTSLGTRKVPTSLKTDASRSGLSSGGSKTHISDESALRMVYGSTPRDEKTTTTKDSITLAKEKEKKIEKRNEEIKLTFKAIRASECVDLLFIVDCTGSMDPYIEQIKSDIVKLQEALKLKHSFLDIEFGFIRYTDFDVASNRCSTFQFSRSTVEFVRFVSEIRAGGGADGPEDVFGGMDLIKSMKWRPNSTRVVIHIADAPCHGTEYHSMADSYPGGDPNGIKLDDLLTDIISLNINYYFGHINLKETGQMIDFFDKKTKEISRNKKSINSFDSKETSKMNERIFISIEESISVSRSVLTEQYLGHNIDGSTGKQRSEREFEINTNMDIDFGELPYIQMLQTKFKMPSDIVTCLSSSYEMKLNEITISIKIAPNPFSHGACRLAYLGIDEHGKKVVLKQSKYIGGRENSKKRYFESMECQTVAAKFALEFNKQLSLTSSEHQITFTVAKVLQMKHSEKPMYFGIETFINGEYQKYNSNCGWLKDDAMSEILQTFSHWTYQESKNKAIVVDIQGVKTSKGYLLTDPAIHSTDTLRFGSCNLGKPGIIKFFQSHKCNQHCKKLGLTIPSFTSSSSTSSSSRSTSSSSSISYSY
What is the function of this protein?
Displays a modest preference for threonine over serine residues.  Does not phosphorylate myosin II, however can phosphorylate MBP, in vitro.  May be involved in the regulation of myosin II function during cytokinesis.  Overexpression leads to impaired cell proliferation in suspension culture and fails to develop beyond the mound stage.  Both overexpression and absence of the gene can result in defects in cytokinesis and alterations in myosin II abundance and assembly.
What are the official names of this protein?
Alpha-protein kinase vwkA, von Willebrand factor A alpha-kinase, vWF kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, perinuclear region. Contractile vacuole membrane. Note=Enriched adjacent to large spherical structures such as contractile vacuoles and Golgi-like structures (perinuclear).
Protein: PNP_METFK
Sequence: MTAIKKTITYGQHELTLETGEIARQADGAVMVSYGDTVVLVSVVGKREVKEGQDFFPLTVDYQEKTYAAGKIPGGFFKREGRPSEKETLTSRLIDRPLRPLFPEAFYNEVQVVATVMSSDPEIDADIPAIIGASAALAISGIPFYGPIGAARVGYINGEYVLNPTASQLKETALDLVVAATESAVLMVESEAKELPEDVMLGSVVYGHEQMQIVISAINELAAEVGKEPWDWAPPEPNTELIAKVEALAGADINEAYKIKSKSARSSKLDEIRSRVLGELITETTSTSEANEIKSIFHNLEAKVVRSQILNGEPRIDGRDTRTVRPISIRTGVLPRTHGSALFTRGETQALVVATLGTGRDEQIIDALQGEYADRFMLHYNMPPYATGETGRVGTPKRREIGHGRLAKRALLAVLPSQEEFGYTIRVVSEITESNGSSSMASVCGGCLSLLDAGVPLKAHVAGIAMGLIKEGNRVAVLTDILGDEDHLGDMDFKVAGTESGITALQMDIKITGITAEIMRVALSQAKEGRLHILGLMKEAVGEQPQELSEFAPRIITMKINPEKIRDVIGKGGAVIRALTEETGTTIDIEEDGTIKIGCTSAEAGEEAKKRIEAITAEVEVGQVYDGTVLKLLDFGAIVSLLPGKDGLLHISQIAHQRVNAVADFLKEGQVVKVKVLEVDDKGRVRLSAKALIEAPSAEAPEEPAVAATGADQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP11_MEDSA
Sequence: DPFSLDVWDPFKDFPFTNSALSASSFPQENSAFVSTRIDWKETPEAHVFKADLPGLKKEEVKVEIEDDRVLQISGERNVEKEDKNDQWHRVERSSGKFMRRFRLPENAKMDQVKAAMENGVLTVTVPKEEIKKPEVKSIEISS
What are the official names of this protein?
18.1 kDa class I heat shock protein.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_BACAC
Sequence: MDHLKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEHVNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDAESHCINYDDVLAKAKEHKPKLIVAGASAYPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGGMILCEEQFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIASLIAYTLKNHENEAALEEARKRVEALTSKFPMYTDL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMPA3_DROME
Sequence: MSEDKMNGRSIRINRLPATIVAILLTFVLVYFLNFHQEERPAIYGMLRSENPSRVNLRKMLIAAIQAAQRGGLEVLDVARSRQLKERSKGKTDEGVNDPFTDADGRSHCVMKQGLQRIFPRVQIFSEEDKEHCKQAHGYDLDPTVLHETAQIPDVTVNAQDVTVWVDPLDATKEFTEELYEYVTTMVCVAVAGRPIIGVIHSPFNGQTAWAWVGNSMSEYLSNLHPQHSPNNQAPIITVSRSHTAGAKDLARGIFGENVSLLTAAGAGYKVLQVVANNATAYLHTSKIKKWDICAGDAILHALGGTMTTLNDQLINYGPEESPVNTEGLLATLEQHDEYMDKLSKYREAHNGKLA
What are the official names of this protein?
Putative inositol monophosphatase 3, IMP 3, IMPase 3, Inositol-1(or 4)-monophosphatase 3, Myo-inositol monophosphatase A3.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DUT_CHLPD
Sequence: MLKVKIVRLNEKALLPVYATTHAAGMDVAACLEENVVVLPFETALIPSGFAIELPEGYEAQLRPRSGLALRHLISLPNTPATIDADYRGEVKIILINYGQEPFVVHHGDRVAQMVVAKVERVFFDEVLTLASSSRADGGFGHTGIAGNPESKA
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: P69_MYCPN
Sequence: MTSLFFYQISDKQKRWNWYWKLALAIIVLVVIIYSFIDNFSGFNVSGFRNFSRNFIRLFTPDTARDYFLGSYLLQTIFYVVSGSILGFVIALWFSYLTAFKIQPLYIALPTRLFTIFLRSFPVLVFAFLFNNLFNKQLTATLTITWFSWLWSTKYITAFFENSALKQFFNQSSRYIHKFKAFWNTVVISQAERLWLFLLYSLEANFRWTTVLSIAGITGIGELIATPLGGTVQLNLVLIPMLTLIGFLLFLEASVFLLTKFVLQKQSQAGDYFLQAKTLQKRKWKKVMIYILALVLAAFTLANLVQLDYTVKAPGFVADFFKQFFQTKTAFLISEDANINPLLMLLKLTTQAISLITLVFVLALLFGFLASKLFSTITSISLKLLLLVIRVIPSVLLFRLFDPIIFRPETTIIFVLAIHSAASYGQLITINFDNANEGVINNMQNHGFSRFYILWNYLIPTTKPQLLNTLSDSFDNAIRDLVVFGIFGGSIIGGRINNFFERAQYSELGTITLPLMVYLMVFEVILMAVRLNKLKVWQRHLW
What is the function of this protein?
Probably part of a high-affinity transport system.
What are the official names of this protein?
ABC transport system permease protein p69.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MILL1_RAT
Sequence: MMLSRDLRAEAAVRLWIMFLLLEDLLGACAVGDYQRRVPSAPNTDIRNTLEKPRVTTQEVAGPHTLRYDLMALSLKLPELPQVLIWRYFDDEPFLHYNESSNRTDSWEPRIKRHWRAMTWARETEDLQEMVEQLKRMLAEVTGQKGQDKGLHILQATLGCELQRNGSTRGFWHLGYDGRNLLTFDQKTLTWTMDMPFTQQKKTFWEPRAPRADLVKTFLDDTCPAQLQRHLASLRSEPLDTGSPMVIVTFRNYPLGRVTLTCRAFNLYPHMATRGTLAWLQDRKLVKQKAFEPGTILPSGDRTYQIWVSIWVLPGQEPQFTCNLSYHGGNIEKRAVIVNTVSGEKTRQPSTSGVGGRVKKSLWTTMTTAFMVTSWTRKTGGDSTLLLLWWLLFFSTVLAVLTLV
What are the official names of this protein?
MHC class I-like protein MILL1, MHC class I-like located near the leukocyte receptor complex 1.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: INT3_DROGR
Sequence: MEQQQQQQQQQKSVAHISKLFVCTAVDCKDEIEEKFERSYVSLQQQIAGLSDKEMHDILTQFVCKEKQHEEISIGFLYIILTDPAMAPKTYRDITLVSRDGMNVIVANLTLLVAEKYAKLTETARRQLIWVLREFVKHQVLSVENVIWNCLRQAGGGDVSHKNLYLVESLLDIFIEYRAWLETNPFLVQSSVYSFVRLIEDHANPALISLRQKEVKFTISLIRDRFHDIIPLGRDFVRLLQNVARIPEFELLWRDILYNPKSLHPTFNGIWHLLQIRTSRRFLQCRLLPEMERKLHFLASSVKFGNQKRYQDWFQDKYFATPESHSLRSDLIRFIINVIHPTNDMLCSDIIPRWAIIGWLISSCTNPIASANAKLSLFYDWLFFDPAKDNIMNIEPGILVMYHSIRNHPFVSSTLLDFLCRITKNFYVKNEDRIRLGVYNSLKLILDKQVIPNLHPLFESPKLDRELRNLIRENFREFVTPVANMPQSMYPATHTIQAPIFKKEADQRLMQGEIMDAGGGGAFVASSGTNMLVDDDNKIAIAPLESMERENEAVFSDDENLPSTSKNEENTDDDDDLPLSKVRLKEKPVPEKVELPDAIAESFEIFVTKRNSFTWEAFLKDFRTLPASALDETQLNYVISNTVLILRETLPQQNVFSESKTEEKYLAKSISYPLYGLFRFLYENEDKSKKPFQTLLSEICGRLTETGYLLLYFMKIHCKLQTRKNAQQSYQFKTTVYRQICEATDEKIGVCLVRDLDLLEKENTTIYLWLLPDIYREFKTIAINNTELLRITLRCIDAKNVRDIMYSIAQGKLTIFKQDGLLDCIRDSLEYETYEQFCLWQLIQAHDVPLKCIQDLLPELEAANHPEALSHLLLLLKNEEPTNEIIRLLLSREAKSRGDPFVTSALRFWCQRCEEKLSEIIASLLTSKYPSSSPNKRKRPSKGSSAASSTPSADHVLNHLEHYRRSCRHGTGTGLYVHDMMQRALQSAYSHSNESTKKQFSDLFALAAEDETTAVGRRGGSGRGRKQPVGKKDSSNHSASSKKNSDVVKTIYSSDENSSEEDWSKHKVTQPAKKRKKAINDSD
What are the official names of this protein?
Integrator complex subunit 3 homolog, SOSS complex subunit A homolog.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 3 family.
Protein: CP6A9_DROME
Sequence: MGVYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKVERV
What is the function of this protein?
Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Cytochrome P450 6a9, CYPVIA9.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: NU5C_ANTAG
Sequence: MQLIYQCAWIVPLCPLISSILIGLGLLFFEKSTKSIRRICAISCILSLSVATVICYNLSYEQIIDNSIYQYSWSWISNGDIVLEFGYLIDPLTCIMLVLVTSVAIIVMIYSDGYMSHDEGYVRFFVYLSLFTASMLGLVLSPNLIQIYIFWELVGMCSYLLIGFWFTRPSAANACQKAFITNRIGDFGLLLGILGFYWITGSFEFENLFKGFKDLLINNEVSPFFAILCASFLFLGPVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIYLVARMFPLFETLPFVMSVISWTGAVTALLGATLAFFQKDLKRGLAYSTMSQLGYMMLALGIGSYRAGLFHLITHAYSKALLFLGSGSVIHSMEPIVGYRPDESQNMIFMGGLRKHMPITGTTFLLGTLSLCGIPPFACFWSKDEIIADSWLYSPFIGWIALLTAGLTSFYMFRIYFLTFEGEFRANSFKENTPVSSVSLWGEFRFEEFGEKKADSVLQIVEKSSPKEFFRFVQSNRESSETQIGNYLSAYPSKEPIHFLYPKESDYTMLIPLLILSIPTLLIGFIGAPLPNGQLGSDLLSHWLNSFGNLSPERLSENWLEFIEDAITSISIASFGIFSAFILYGPASIFPRDLEKKIEPQLKGVWGFFINYMYNWSQYRGYIDQYYNKIFVEGTRILAYASSFFDRWIIDGIVNGTGISSFSGGEGMRYGEGGRVSSYLFGLVFGMTILLAVILLII
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: THIE_BACSU
Sequence: MTRISREMMKELLSVYFIMGSNNTKADPVTVVQKALKGGATLYQFREKGGDALTGEARIKFAEKAQAACREAGVPFIVNDDVELALNLKADGIHIGQEDANAKEVRAAIGDMILGVSAHTMSEVKQAEEDGADYVGLGPIYPTETKKDTRAVQGVSLIEAVRRQGISIPIVGIGGITIDNAAPVIQAGADGVSMISAISQAEDPESAARKFREEIQTYKTGR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).  Is also able to use the 2-methoxy analog MeO-HMP-PP, as substrate in vitro, but not the 2-trifluoromethyl analog CF(3)-HMP-PP.
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RS6_POLAQ
Sequence: MRHYEIVFIVHPDQSEQVPAMIDRYKATLAAAGGKIHRIEDWGRRQMAYMIDKLAKAHYVCMNIECDQKTLEELEHAFKFNDAVLRHLIIKTKKAETEPSIMMKEVQREEARKSAQSDAPAVAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TRAP1_RAT
Sequence: MARELRALLLWGRGLQSALRAPALAGVRRGKPVLHLQKTTVHFRDPTQSLASGISAGQLYSTQAAEDKKEEALHSIISNTEAVQGSVSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKRVCEGQVLPEMEIHLQTDAEKGTITIQDTGIGMTKEELVSNLGTIARSGSKAFLEALQHQAETSSRIIGQFGVGFYSAFMVADKVEVYSRPAAPESPGYQWLSDGSGVFEIAEASGVRPGTKIIIHLKSDCKDFANESRVQDVVTKYSNFVSFPLYLNGRRINTLQAIWMMDPKDISEFQHEEFYRYIAQAYDKPRFILHYKTDAPLNIRSIFYVPEMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFVRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTTAEQDIKEDIAKLLRYESSALPAGQLTSLSDYASRMQAGTRNIYYLCAPNRHLAEHSPYYEAMKQKQTEVLFCYEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDTSPAGERLSEKETEELMAWMRNALGSRVTNVKVTFRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHTLIKKLNQLREREPELAQLLVDQIYENAMIAAGLVDDPRAMVGRLNDLLVKALERH
What is the function of this protein?
Chaperone that expresses an ATPase activity.  Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I.  Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis.  The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
What are the official names of this protein?
Heat shock protein 75 kDa, mitochondrial, HSP 75, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Mitochondrion matrix.
Protein: RS19_RENSM
Sequence: MPRSLKKGPFVDQHLFVKVANENEKGTKNVIKTWSRRSMIIPDMLGHTIAVHDGRKHIPVFVTESMVGHKLGEFALTRTFRGHVKDDRKGKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YBJQ_SALG2
Sequence: MQFSTTPTLEGQSIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFQELGEQAKALGADAVVGIDIDYETVGKDGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RL18_COXBR
Sequence: MDKQEKRIRRARRTRAKIKELGAVRLCVHRSLNHIYAQLISPRDSKVLVCASTLEKEVRSQIKHGGNIQAATAIGKLIAQRAKKAGVTKVAFDRSGYKYHGRVRALAEAVREGGIEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: VAPA_HUMAN
Sequence: MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL
What is the function of this protein?
Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (PubMed:25447204).  The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204).  With OSBPL3, may regulate ER morphology (PubMed:16143324).  May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470).
What are the official names of this protein?
Vesicle-associated membrane protein-associated protein A, VAMP-A, VAMP-associated protein A, VAP-A, 33 kDa VAMP-associated protein, VAP-33.
What is the protein family that this protein belongs to?
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cell membrane; Single-pass type IV membrane protein. Cell junction, tight junction. Nucleus membrane. Note=Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells.