PharMolix/UniProtQA huggingface dataset:
Protein: MTNN_EXIS2
Sequence: MPIAIIGAMEEEVNLLRNELSERKDTVIANYHFYEGLLNSVPVVILKSGIGKVNAAIGTTLLLDHFKPSSVINTGSAGGFRAGLKVGDVVVSTEVRHHDVDVTAFGYEYGQVPGMPAAYTADPKLIATAEAVIERMDAIRVVHGLIVTGDSFIHDTERSNLIKTNFPDVAAVEMEAAPIAQVCHQFDVPFVVTRSISDSADEEASLSFDEFLEIASINSAKMVMEVVRTLADSE
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: Y1307_HAEIN
Sequence: MMLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLFVTIPALHGVIMLLGGSYLAYLGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNLSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFCYFYVISLIFSRNIAKRLYSQYSRYIDNMAGIVFLFFGCVLVYNGINEIIH
What are the official names of this protein?
Uncharacterized membrane protein HI_1307.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRT21_ARATH
Sequence: MGDSTGEPGSSMHGVTGREQSFAFSVQSPIVHTDKTAKFDLPVDTEHKATVFKLFSFAKPHMRTFHLSWISFSTCFVSTFAAAPLVPIIRENLNLTKQDIGNAGVASVSGSIFSRLVMGAVCDLLGPRYGCAFLVMLSAPTVFSMSFVSDAAGFITVRFMIGFCLATFVSCQYWMSTMFNSQIIGLVNGTAAGWGNMGGGITQLLMPIVYEIIRRCGSTAFTAWRIAFFVPGWLHIIMGILVLNLGQDLPDGNRATLEKAGEVAKDKFGKILWYAVTNYRTWIFVLLYGYSMGVELSTDNVIAEYFFDRFHLKLHTAGLIAACFGMANFFARPAGGYASDFAAKYFGMRGRLWTLWIIQTAGGLFCVWLGRANTLVTAVVAMVLFSMGAQAACGATFAIVPFVSRRALGIISGLTGAGGNFGSGLTQLLFFSTSHFTTEQGLTWMGVMIVACTLPVTLVHFPQWGSMFLPPSTDPVKGTEAHYYGSEWNEQEKQKNMHQGSLRFAENAKSEGGRRVRSAATPPENTPNNV
What is the function of this protein?
Involved in nitrate transport, but does not seem to be able to mediate transport by its own.  Acts as a dual component transporter with NTR3. 1.  Acts as a repressor of lateral root initiation under high sucrose/low nitrate conditions.
What are the official names of this protein?
High-affinity nitrate transporter 2.1, AtNRT2:1, Protein ACH1, Protein LATERAL ROOT INITIATION 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RDH10_MOUSE
Sequence: MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGKGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMRAILTDQPMVCTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI
What is the function of this protein?
Retinol dehydrogenase with a clear preference for NADP.  Converts all-trans-retinol to all-trans-retinal.  Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol (By similarity).  Required for normal embryonic development.
What are the official names of this protein?
Retinol dehydrogenase 10.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: BAUC_PSEAE
Sequence: MGTLHHLINGEMVADNGRSADVFNPSTGEAIHKVPLADGKTLQKAIDAARAAFPAWRNTPPAKRAQVLYRFKQLLEQNEARISKLISEEHGKTLEDAAGELKRGIENVEYACAAPEILKGEYSRNVGPNIDAWSDFQPIGVVAGITPFNFPAMVPLWMYPLAIACGNTFILKPSERDPSSTLLIAELFHEAGLPKGVLNVVHGDKEAVDGLLQAPEVKAISFVGSTPIAEYIYAEGTKRGKRVQALGGAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMAISVAVCVGDQVADALIAKLVPQIKALKIGAGTSCGLDMGPLVTAAAQAKVTGYIDSGVAQGAELVVDGRGYQVAGHENGFFLGGSLFDRVTPEMTIYKEEIFGPVLCVVRVNSLEEAMQLINDHEYGNGTCIFTRDGEAARLFCDEIEVGMVGVNVPLPVPVAYHSFGGWKRSLFGDLHAYGPDGVRFYTRRKAITQRWPQRASHEASQFAFPSL
What is the function of this protein?
Involved in the degradation of beta-alanine.
What are the official names of this protein?
Putative 3-oxopropanoate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: KDPA_ECO24
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANB_CLOBK
Sequence: MRNTVSTFQELKNKGEKITMLTAYDYSMAKLIDSSGINGILVGDSLGMVCLGYENTLSVTMEDMLHHTKAVVRGTSNALVVGDMPFMSYQTSIYDAVYNAGRFIKEAGAHAVKLEGGATVAEEIKAIVKAQIPVMGHIGLTPQSVNMFGGFKVQGKNEKVAKKLIEDAKILEEAGAFSIVLECIPEKLSKIISESISIPTIGIGAGKYCDGQILVYQDMLSMFSDFKPKFVKSFGNIGESIKDGVSQYIKEVKEAKFPEEKHAFKIDDDVINKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_PYRAB
Sequence: MKEELVKLIIDSGCIKFGHFILTSGKESNYYIDIKSLITNPKALKLIAKMIKEESRKLGIEYDKVAGPELGAVPIATALSLETDKPLLIIRKKKKEHGTGKLIEGEISPGDRVLLVEDVTTTGGSVIRAAKILKEHGAEVVGIFVVVDREEGARENIEKEGFKLYPLVLVSDLFEAAGVSKD
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: FEN_SULAC
Sequence: MDLGEIVEDVKREINLNEMKGKKISIDAYNTIYQFLAAIRQPDGTPLIDSKGRITSHLNGLFYRTISIIESGIIPIFVFDGKPPEKKSEEIERRKRAKEEAEKKLEKAKLEGEYREIRKYAQAAVRLSNEMVEESKKLLDAMGIPVVQAPGEGEAEAAYINSIDLSWAAASQDYDSLLFGAKRLVRNITISGKRKLPNKDVYVEIKPELIELESLLKKLGINREQLIDIAILIGTDYNPDGVKGIGVKTALRIIKKYNNIENAIEKGEIQLSKINFDIREIRKLFITPEVKKPTERLELAECNEREIIELLVKNHDFNEDRVNNGIERLKKAIKEAKSVEKQTGLDQWF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: LFTR_SULDN
Sequence: MIPKLLKHELTFPHPNDATEDGIVAWGGDLNPSRLIRAYQNGIFPWYGKNDPIIWWSPNPRLIMELDDFKLSRSLRKSMKKFEYRFDTNFINVMKNCQNIKRVKQDGTWIQDEIIEAYSVLHDMGIAHSVESYLDGELVGGLYGVAVGGLFCGESMFTLVNDASKSAYAVLINHLKIWGYDFIDAQVPTEHLKNLGAKEVSRDYFLDRLHKVNMNIINHKWELLHVNT
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDN2A_HUMAN
Sequence: MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD
What is the function of this protein?
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6.  This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A, CDK4I, Multiple tumor suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A.
What is the protein family that this protein belongs to?
Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Protein: SYI_CHLMU
Sequence: MDNEDKVSFPAKEEKVLTFWKEQNIFQKTLENRDGSPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYATMDGHYVPRRFGWDCHGVPVEYEVEKSLGLTEPGAIDRFGIANFNEECRKIVFRYVDEWKYFVDRIGRWVDFSATWKTMDLSFMESVWWVFHSLYKQGLVYEGTKVVPFSTKLGTPLSNFEAGQNYKEVDDPSVVAKFALQDDQGILLAWTTTPWTLVSNMALAVHPGLTYVRIQDKESGEEYILGQESLARWFPDRESYKWIGQLSGESLVGRRYCPLFPYFQDQQDRGAFRVIPADFIEESEGTGVVHMAPAFGEADFFACQEHNVPLVCPVDNQGCFTSEVTDFVGEYIKFADKGIARRLKNENKLFYQGTIRHRYPFCWRTDSPLIYKAVNSWFVSVEKVKHKMLKANESIHWTPGHIKHGRFGKWLEGARDWAISRNRYWGTPIPIWRSEDGELLVIRSIQELEELSGQKIVDLHRHFIDEIVIHKNGKSFHRIPYVFDCWFDSGAMPYAQNHYPFERAEETEARFPADFIAEGLDQTRGWFYTLTVIAAALFDQPAFKNVIVNGIVLAEDGNKMSKRLNNYPSPKKIMDTYGADALRLYLLNSVVVKAEDLRFSDKGVEAVLKQVLLPLSNALAFYKTYAELYGFSPNETTDLELAEIDRWILSSLYSLVGKTRENMAQYDLHAAVSPFIDFIEDLTNWYIRRSRRRFWESEDSPDRRAAFATLYEVLMVFSKIIAPFIPFTAEDMYQQLRVETDPESVHLCDFPHVVLEKILPDLEKKMQDIREIVALGHSLRKEHKLKVRQPLQHMYIVGAKERMAALAQVDSLIGEELNVKEVHFCSETPEYVTTLVKPNFRSLGKRVGNRLPEIQKALAGLSQEQIQAFMHNGFMVLSLGEETISLNEEDITVSWEAAPGFVARSSASFVAILDCQLTSPLIMEGIAREIVNKINTMRRNGKLHVSDRIAIRLHAPKIVQEAFSQYEEYICEETLTTSVSFIDDKEGEEWDVNGHAVSLSLEVIGH
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_MARMM
Sequence: MGQKVNPIGLRLGVNRTWESRWYAGAGEYAKLLHEDIKIRKMLKERLKNASVSKIVIERPHKKCRVTVHTARPGVVIGKKGSDIETLRKELSKMIDGEVHLNLVEVRKPEIDAALVAESIAQQLERRVAFRRAMKRSMQSAMRMGAKGCKIVCGGRLGGAEIARTEQYNEGSVPLHTLRADIDYGTCEAKTAMGIIGIKVWIYKGEIMEHDPNAQERRLQESGEQRARSGRQAA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: YIDC_PSESM
Sequence: MDIKRTILIVALAIVTYVGVLKWNQDYGQAAMPTQNVAASNTAPGIPDTAAGNNGSASADVPSATGNTTSAAPLETPAVASKDLIHVKTDVLDLAIDPVGGDVVQLRLPLYPRRQDRPDVPFQLFDNGGERTFLAQSGLTGTNGPDARASGRPVYSSAQKSYQLADGQDSMVVELKFSENGVNYIKRFTFKRGLYDLVMTYVVDNQSAQPWAGNLFAQLKRDASSDPSSTTATGTATYLGAALWTAAEPYKKVSMKDIDKGQIKENVQGGWVAWLQHYFVTAWIPDHNVTNAVQTRKDSQGNYIIGFTSPTLSVAPGAQGETTATLYAGPKSQAVLKELSPGLELTVDYGFLWFIAQPIFWLLQHIHAILGNWGWSIIVLTMLIKGLFFPLSAASYKSMARMRAVAPKLAVLKEQHGDDRQKMSQAMMELYKKEKINPLGGCLPILVQMPVFLSLYWVLLESVEMRQAPWILWITDLSIKDPFFILPIIMGATMFIQQRLNPTPPDPMQAKVMKMMPIIFTFFFLWFPAGLVLYWVVNNTLSIAQQAYITRKIGAATKKAAA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECG_RICPR
Sequence: MIDIFLFVHITISILLIIVILMQRSGSGGISGISGDNNMGVVSAKTVGNFLSKSTIILTTLFLINAIVLANLSAKKQSDLVSKINEIEENQADNSLPIAK
What is the function of this protein?
Involved in protein export.  Participates in an early event of protein translocation (By similarity).
What are the official names of this protein?
Protein-export membrane protein SecG.
What is the protein family that this protein belongs to?
Belongs to the SecG family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAJ_SACD2
Sequence: MSKRDYYEVLGVSKDVSPQELKKAYRKVAMKYHPDRNSDDPNSEDKFKEASEAYEVLSDAQKRAAYDQYGHAGVDGNAGMGGGAGAGNFSDIFGDVFGDIFGGGGGRRRGGPSRGSDLRYTLDLSLEDAVKGTTVKIRVPTLVSCKPCGGSGAKPGTSPQTCTTCGGHGQVRMQQGFFSVQQTCPNCRGQGKMITDPCKECHGHGRVEETKTLSVKVPPGVDTGDRIRLAGEGEAGADGGPAGDLYVQVDVQDHAFFQREGRNLYCEVPISLFDACLGGELEVPTLDGRVKLKIPAETQTGKLFRLRGKGVTPVRGGAAGDLMCRVIIETPVNLTKKQKELLEELKASMKGEKNSPKQESWFEGMKNFFGDLKM
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP18_SCHPO
Sequence: MSFFGLKRYSTPILKPMLPFFLGGAIVFYGTVKLRDAMMDSAEYRNDPRNPKAGKYGSDH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane.
What are the official names of this protein?
ATP synthase subunit J, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase j subunit family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: COBT_MYCLB
Sequence: MEFAPVSPPDGHAAAAARARQDTLTKPRGALGRLEDLSIWVASCQGQCPPRQFQRARIVVFAGDHGVARSGVSAYPPQLTAQMVANIDRGGAAINALASIADATIRIADLAVDADPLSQQIGIHKVRRGSGDIAIQDALTEDETARAIIAGQRIADEEVDRGADLLIAGDIGIGNTTAAAVLVAALTNAEPVAVVGFGTGIDDASWARKTAAVRDALCRIRLVLPDPVGLLRCCGGADLAAMAGFCAQAAVRRTPLLLDGMVVTAAALVAERLAPGSWQWWQAGHQSTEPGHALALAALDLDPILDLRMRLGEGTGATAALLVLRAAVAALTSMTTFAEAGVAGTSTSPPS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: SOSSC_DROSE
Sequence: MAFPTTSAQQAETNRKILEEIQTKKQLLAGGIINLGLSPPNQMPAPQLLGQPTTVNPDFQAGVGIATNATSTTRSAFNPTSSTTLGFFIPQDSYFGNSFIPVLPRLEPLPSPATTPTAPPSHSISK
What are the official names of this protein?
SOSS complex subunit C homolog.
What is the protein family that this protein belongs to?
Belongs to the SOSS-C family.
Protein: ENCC_ASPFU
Sequence: MASVQGLIKIVAITGGVWLSGKITAHSLVSVPALLQTRSADGLSPCTILRVWRRIYEQGHRHSPQIAACTSTAFAYLAWCASDRTPRLLYGTAACSVMGIVPYTLLFMGPTNSRLLERSAAEEEKVPGATRGEDMVNVPSEMTTEELLSHWRFLAGIRGLLPLAGGILGLFAALYSNEGAR
What is the function of this protein?
Anthrone oxygenase; part of the gene cluster that mediates the biosynthesis of endocrocin, a simple anthraquinone interesting for many biotechnological applications (PubMed:22492455, PubMed:23592999).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) encA (PubMed:22492455).  The atrochrysone carboxyl ACP thioesterase encB then breaks the thioester bond and releases the atrochrysone carboxylic acid from encA (PubMed:22492455).  The atrochrysone carboxylic acid is then converted to endocrocin anthrone which is further oxidized into endocrocin by the anthrone oxygenase encC (PubMed:22492455).  The exact function of encD has not been identified yet, but it negatively regulates endocrocin production, likely through the modification of endocrocin itself (PubMed:22492455).
What are the official names of this protein?
Anthrone oxygenase encC, Endocrocin synthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the anthrone oxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPAN_SHISO
Sequence: MALDNINLNFSSDKQIEKCEKLSSIDNIDSLVLKKKRKVEIPEYSLIASNYFTIDKHFEHKHDKGEIYSGIKNAFELRNERATYSDIPESMAIKENILIPDQDIKAREKINIGDMRGIFSYNKSGNADKNFERSHTSSVNPDNLLESDNRNGQIGLKNHSLSIDKNIADIISLLNGSVAKSFELPVMNKNTADITPSMSLQEKSIVENDKNVFQKNSEMTYHFKQWGAGHSVSISVESGSFVLKPSDQFVGNKLDLILKQDAEGNYRFDSSQHNKGNKNNSTGYNEQSEEEC
What is the function of this protein?
Required for surface presentation of invasion plasmid antigens.  Could play a role in preserving the translocation competence of the ipa antigens.  Required for invasion and for secretion of IpaB and IpaD proteins (By similarity).
What are the official names of this protein?
Surface presentation of antigens protein SpaN, Spa32 protein.
What is the protein family that this protein belongs to?
Belongs to the SpaN family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: PURA_BORPD
Sequence: MSKNVVVIGTQWGDEGKGKIVDWLAESVQGVVRFQGGHNAGHTLWINGKKTILRLIPSGIMHPGVTCFIGNGVVLSPEALLKEIEELEAAGLDVRSRLQISEICPLILPYHIAVDQAREARKGEGKIGTTGRGIGPAYEDKIARRALRVQDLFNPALFDEKLAELLDYHNFVLTQYLGAPAVSAAQVRDQAMALAPAIAPMVKDVSSNLYAMQQAGQRLLFEGAQGALLDVDHGTYPFVTSSNCLAGAASAGAGVGPQSLDYVLGITKAYTTRVGSGPFPTELVDEIGTRLATIGKEFGSVTGRPRRCGWFDGAALKRSVRLNGITGLCITKLDVLDGLESIQLGVGYRVNGEFRDVLPYGAHAVAQAEAVLEELPGWSESTVGITEYAKLPAAARRYLERVAEVCGVPIDLVSTGPDRNETIVLRHPLKG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_CUPPJ
Sequence: MASKGGRDKIKLESTAGTGHFYTTTKNKRTMPEKMEIMKFDPVARKHVAYKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.