PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_PECAS
Sequence: MSEIFIYPQATCIAGVDEVGRGPLVGAVVTAAVILDPTRPIVGLADSKQLSEKRRLSLYDEIKEKALAWSLGRAEPEEIDQLNILHATMLAMQRAVAALAIVPDFVLIDGNRCPALPMPAQAVVKGDSRVAEISAASIMAKVTRDREMVELDQRFPDYGFAQHKGYPTAFHLEKLAALGATEFHRRSFAPVKRVLGLA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_SHEHH
Sequence: MLDPKFLRNELEVTAERLATRGFILDVERLGKLEDKRKSLQVATEELQASRNAISKSIGQAKAKGEDVAPIMAQVGSLGEELDAKKAELASLLDELNSIAMSVPNLPDESAPIGADESENVEVRRWGTPKEYDFEVKDHVELGENIGGLDFKNAVKITGSRFIVMKGQIARMHRALAQFMLDLHTTEHGYTEAYVPLLVNEDSLMGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNLVRDTIVDEEELPIKLTAHTPCFRSEAGSYGRDTRGLIRQHQFDKVELVQLVKPENSMQALEELTAHAETVLQKLGLPYRTVVLCTGDMGFGSSKTYDIEVWLPAQNTFREISSCSNMQDFQARRMQARYKAKTDKKPSLLHTLNGSGLAVGRTLVAVIENYQNADGSITVPEALRGYMGGLEKIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPT35_CANGA
Sequence: MADKVAVLDPEPITLLDTEDEPGISQSRRSSIANSNFYIERAFVTNCTIISGERSTPKFAVWKVTAVLHPLNPNSSGSYRIHTYKRYSDFVEFRNALLDRVRTKRPASVSEIPELPPPVKWYYSWKYNEINLNKEWLANRRKGLELFINQVLLNGNIVDIAKDLVIQFLRPRK
What is the function of this protein?
Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
What are the official names of this protein?
Endosomal/vacuolar adapter protein YPT35, PX domain-containing protein YPT35.
What is the protein family that this protein belongs to?
Belongs to the YPT35 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: DER_PARDP
Sequence: MSFTLAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDLREGAGRLGDLRFIVVDSAGLEIAEDDSLQGRMRRLTERAVDEADVCLFVIDARVGVTAADEYFADILRRRARHVILAANKAEGRAGEAGAMEAYALGLGEPLRISAEHGEGMDDLYRALVPLAEAFEAQNVQQAPETDVAVEDGDDETEDWRPSESKPLQIAVIGRPNAGKSTLINKILGEDRLLTGPEAGITRDSISVSTNFMGTPVRIFDTAGMRKKARVTDKVEKLSVADGLRAVRFAEVVVVLLDVGIPFEQQDLRIADFAETEGRAVVVAANKWDLEEDKPEKLKELREAFERLLPQLKGAPLVTVSARTGKGLDRLHNAILKAHEVWNRRIPTARLNQWLSTMTEAHPPPAPGGRRIRLRYITQVKTRPPAFVVMATHTDKLPDSYQRYLVNGLRQDFDMPGTPIRLTFRDQGTKNPYKDKASKINQSGALSKHKHRQKPKGS
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: NUOB_BRUA2
Sequence: MGLTGTNTTLVAPQPKGILDPRTGKTVGSDDAFFNDLNGELSDKGFIVTSADALITWARTGSLMWMTFGLACCAVEMMHISMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRVVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ANP8_ELEGR
Sequence: AATAATPATAATPARA
What is the function of this protein?
Antifreeze proteins lower the blood freezing point.
What are the official names of this protein?
Ice-structuring glycoprotein 8R, ISGP 8R, Antifreeze glycoprotein 8R.
What are the subcellular locations of this protein?
Secreted.
Protein: RHN1_NICPL
Sequence: MASSSHNNLNAKLVLLGDMGAGKSSLVIRFVKGQFLEFQESTIGAAFFSSTLAVNNATVKFEIWDTAGQERYHSLAPMYYRGAAAAIIVYDITSSDSFARAKKWVQELQKQGNPNMVMALAGNKADLEDRRKVTAEEARLYAEENGLFFMETSAKTAVNVNAIFYEIAKRLPRAQPAQNPAGMVLVDRAAEGTRATSCCT
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein RHN1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MSCL_PHEZH
Sequence: MSIISEFREFIARGNVIDLAVGVIIGAAFNDIVKALVDNIVMPPIGLVLSGIDFSDLAWVLKPDDPATPALDAVAIQYGAFINTCIRFLIVAWAVFMLVKLVNVIRRREAEKPPEEKPAPTPQETLLMEIRDLLKRRAD
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPB_PROMM
Sequence: MPIDIGKLGTTSTSAQSQSTFLFECSEPVPFEMAWLWQQQWQQQLFANPLAPQAVWLLQHQACYTLGRGASEANLLFDVNNPPAALHRIDRGGEVTHHLPGQLVVYPVLDLRRYQTDLHWYLRQLEQVLIDVLAVLGLAGERLQGLTGLWLEGRKVAAIGVGCRRWITQHGLALNVDCDLESFSAVVPCGLVGHPVGRLNQWIPGLTMAEVQPLMRQSLSDRFGLVWQIPEPLAKPGAFASDA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UGPB_SHIF8
Sequence: MKPLHYTASALALGLALMGNAQAVTTIPFWHSMEGELGKEVDSLAQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIKPVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYSAKLKASGIKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDGTDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKPENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGNMPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Binds G3P.
What are the official names of this protein?
sn-glycerol-3-phosphate-binding periplasmic protein UgpB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: IDI_ECOLI
Sequence: MQTEHVILLNAQGVPTGTLEKYAAHTADTRLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDFRYRATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSPWMVMQATNREARKRLSAFTQLK
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEA_SHEB2
Sequence: MNDWSIDDARAGYNVTHWSQGFYGISDHGEVTVSPDPKNPDYKIGLNELAKDMVKAGVALPVLVRFPQILHHRVNSLCQAFDQAIQKYEYQADYLLVYPIKVNQQQTVVEEILASQASKEVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIRLALIGEKLGHKVYIVLEKLSELKMVLAESKRLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILLVVEQLKQNDMLDSLQLLHFHLGSQIANIRDIRQGVSEAGRFYCELRALGASVNCFDVGGGLAVDYDGTRSQSNNSMNYGLTEYANNIVNVLTDICNEYEQPMPRIISESGRYLTAHHAVLITDVIGTEAYQPEDIQPPAEESPQLLHNMWHSWSELSGRADQRALIEIYHDSQSDLQEAHSLFALGQLSLAERAWAEQANLRVCHEVQGLLSAKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGIDQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSADSPYLIGFFLVGAYQEILGDMHNLFGDTNSAVVRIEDNGVTNIESVLAGDTVADVLRYVNLDAVAFMRTYEELVNLHIAEDERAQILEELQVGLKGYTYLEDFS
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: RS18_BURL3
Sequence: MPRPTGKKFDKRRQQQNPLFKRKKFCRFTAAGVEQIDYKDTETLKDFIGENGKITPARLTGTKAHYQRQLDTAIKRARFLALLPYTDQHKA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RS19_SHEFN
Sequence: MPRSLKKGPFIDLHLLKKVEKAMEAGDKKPIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTDEMIGHKLGEFSPTRTYRGHAADKKAKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MCC25_ARATH
Sequence: MGKQLAKKITWAIENFSSLHSKKIYSDPFIVGGCKWRFLVYPKGNNVDYLFLYLEVADYESLSPEWRRHARYLLNVVNQNSVKRSKQNEEQKWFDVQSPRWGRLSMFPLNEINAKDSGFLVNGELKIVAEIEVLEVIGKLDVSEETSTIMESMDFNGFQLLPSQVDFVRHMFEKHPEIASEFRLKNPNLRAGYMSLLLSLIETLRQSPQELNKVDLAEGYVALRSITDAGFKVDWLEKKLVEISEKKNKEEAGETRMQEINEELESLKQKCLDLEAQLEKEKAEVFAAKSPLSFNDVF
What are the official names of this protein?
MATH domain and coiled-coil domain-containing protein At3g58360, RTM3-like protein At3g58360.
Protein: SLMA_ECO45
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYATDETLLASQILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HSLU_BACAN
Sequence: MHLHFTPRQIVEKLDQYIIGQKDAKKAVAVALRNRYRRSKLAENLRDEIAPKNILMIGPTGVGKTEVARRMAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSVRIVKEEMVVKVQDKAEEQANQRLVEILVPSPEKQSGFKNPLEMLFGGTQNSNQTTDSQEDVEIEKKRQDVERKLAAGLLEDEIVSIEVTEQQSSMFDMLQGTGMEQMGMNFQDALGSFMPKKTKKRKLSVKEARKVLTNEEAQRLIDMDEVTQEAVYRAEQLGIIFIDEIDKIAGKQSNSVDVSREGVQRDILPIVEGSNVATKYGSVKTDYILFVAAGAFHMSKPSDLIPELQGRFPIRVELTKLSTDDFVKILIEPDNALIKQYMALLATEGIEIEFSDEAIRKIAEIAYQVNQDTDNIGARRLHTIMEKLLEDLSFEASEITLEKITITPQYVEEKLATIAKNKDVSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_EHRCJ
Sequence: MSASPLDQFKILTIFKLPNIAGYNIDFTNASLFMVLSTISVALFCYIGLKKESIIPNGIQSIVEFIYEFIVSTIESNVGKEGLQYIPLVFTIFMFIATCNLLGILPLGFTATSHIAVTFAISMVVFVSVTIIGFKHQGIHFLRILLPQGTPGWLAPMMVFIELFAYCARPVSLSIRLAANMIAGHTIIKVIAGFVVKMNIFLTPLPMIFIIILIGFEIFVAILQAYIFTVLTCVYLSDAVKEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LGT_LIMRJ
Sequence: MINQGIKAALNPIAFQGGPFTIHWYGVIIASGVVLALLLAVREGKREGIPEDDFYDYLLWALPIAIICARIYYVVFQWSYYSQHPSEIIAIWDGGIAIYGAILGGFIVLLVFCHYRHLSSWLMMDIIAPTLIMAQGIGRWGNFMNQEAFGDITTRAHLMAQHIPNWIINQMYIGGHYRIPTFLYESLWDLTGFALLMLLRHRKHLFRRGEIFLTYVMWYAFGRFFIEGMRTDSLMLGSIRISQLLSIVFFVSALIILIIRRHKNIPWYYNGINKN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS6_SALAR
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYSAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMIMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: DBND1_RAT
Sequence: MESPEGAGPGEITKEVKVPQAAPSVPAHETGDTCHTPVAAVEEEVGIPIPAPGFLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLATESPAGLHPLSRASCLRSPSWTKTRAEQNREKQTPSDPERQGTIVDTFLTVEEPKED
What are the official names of this protein?
Dysbindin domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the dysbindin family.
Protein: DGCR8_HUMAN
Sequence: METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSELPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESADKKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYEDDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKDNEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNHISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKHTVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQYAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV
What is the function of this protein?
Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis.  Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus.  Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs (PubMed:26027739, PubMed:26748718).  The heme-bound DGCR8 dimer binds pri-miRNAs as a cooperative trimer (of dimers) and is active in triggering pri-miRNA cleavage, whereas the heme-free DGCR8 monomer binds pri-miRNAs as a dimer and is much less active.  Both double-stranded and single-stranded regions of a pri-miRNA are required for its binding (PubMed:15531877, PubMed:15574589, PubMed:15589161, PubMed:16751099, PubMed:16906129, PubMed:16963499, PubMed:17159994).  Specifically recognizes and binds N6-methyladenosine (m6A)-containing pri-miRNAs, a modification required for pri-miRNAs processing (PubMed:25799998).  Involved in the silencing of embryonic stem cell self-renewal (By similarity).
What are the official names of this protein?
Microprocessor complex subunit DGCR8, DiGeorge syndrome critical region 8.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Colocalizes with nucleolin and DROSHA in the nucleolus. Mostly detected in the nucleolus as electron- dense granular patches around the fibrillar center (FC) and granular component (GC). Also detected in the nucleoplasm as small foci adjacent to splicing speckles near the chromatin structure. Localized with DROSHA in GW bodies (GWBs), also known as P-bodies (PubMed:17159994).
Protein: SWP12_ENTBH
Sequence: MYQETKRYIERKLKKIEYIYTKLPDGYEDIEIRYRKVRDEIGILQNVVNGLTYYEYGGTVMKNVAHWANIVGESTNINAIKREDIYTNTSTVGMQLAHTVSDKSLKEVCTEFSTAYENIAIEKRKMNEKMEDVTDELNNLKKKCKQIDHQRHIVKNIRYDLEELLQSNVYKEDIKNRLEKKLESNGKEIQEQMTDFVHLSMINGIIVKIAKIHKEFCEAAGNHLEKFN
What are the official names of this protein?
Spore wall protein 12.
What is the protein family that this protein belongs to?
Belongs to the SWP12 family.
What are the subcellular locations of this protein?
Spore wall.
Protein: GATC_LACPL
Sequence: MAEERINAEQVQHVASLAKLEFTPDQLAMFTPQLEKIIGMFEELSTVDTTGVPVTSRMSDHTNTLREDVAVKSDEALREALLKNAPETANGLIKVPAIIDESGDGE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: ISPH_MYCLE
Sequence: MPPTVNMGIPGASRSIVENLKRKRVLLAEPRGYCAGVDRAVETVERSLRKYGPPVYVRHEIVHNRHVVETLERAGAVFVEETDYVPEGAIVIFSAHGVAPTVYAAAAERNLRTIDATCPLVTKVHNEVKRFARNDYDILLIGHEGHEEVIATAGEAPTHVQLVDGLAAVQQVVVRDENKVVWLSQTTLSVDETMRIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVAMGSGAGAAYLVDWAKDIDPAWLAGVTTVGVTSGASVPDILVQGVLKWLAERGYDVVQSVTTANEALVFALPREIRSAH
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MURB_SOLUE
Sequence: MRLAGIPNLAVSASTPLSLYTRFGIGGPADLFAETRDEGAFMAAIAAARESGTAVMVTGGGTNLIVSDAGFRGLVVRFADDTLSAEAERVTAGAGAVLQDLIDFANHRGLKGLETLAGIPGWVGAAVYGNAGAYGHSISERVRAVRFFDGSAVRIFDHAQCEFAYRESIFKRHKDWIIFSAELVMDAGEAGELERTSADILKVRNEKFPPTMKCAGSIFKNFLITELPPPVAGLVPANVVREGKVPAAWFLEQVGAKGMRFGGIRVADYHANLIYNAGEGTARELCAVIAELKGRVRERFGIEVEEEVQYVG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_CAMC1
Sequence: MKNLLDLSIEELKELVSPSFRATQIYEWVYKKNATEFSQMLNLPKDMRQDLAEKFYLDPLKCVKFEQSSDGSIKYLFELKDGLKIESVLLPMKEEISDEDGKISRHARYTICVSSQVGCKMGCAFCLTAKGGLVRNLTAGEIVGQILWIKRENKIPYERRINVVYMGMGEPLDNLTNVSKAIKILALNEGLAISPRRQTVSTSGLGSQIKKLGEMDLGVLLAISLHAVTNELRSRLMPINKAYNIEAVMDAVRGFPIDMRKRVMFEYLVIKDLNDSVSDAKKLVKLLHGIKAKVNLIYFNPHEGSEFGRPELASMLKFQEYLRDHGVTCTIRQSKGLDISAACGQLKQRNENPKFRANVSGNSAAKTEEKPTNDKTNVSKK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGD13_ARATH
Sequence: MSNYAAGLGKPGSGKRRIRDLLNQPDNRVCADCGASDPKWASANIGVFICLKCCGVHRSLGTHISKVLSVTLDEWSDEEVDSMIEIGGNASANSIYEAFLPDTCSKPGPDVNHDQRMRFIRAKYELQEFLKPSLRITSGKGSTKSSAFLTSSLSRKIMDSFRTNSSSQTMFQEGMVEFIGLLKVTIKKGTNLAIRDMMSSDPYVVLNLGKQKLQTTVMNSNLNPVWNQELMLSVPESYGPVKLQVYDYDTFSADDIMGEADIDIQPLITSAMAFGDPEMFGDMQIGKWLKSHDNPLIDDSIINIVDGKVKQEVQIKLQNVESGELELEMEWLPLDQ
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor (ARF).
What are the official names of this protein?
Probable ADP-ribosylation factor GTPase-activating protein AGD13, ARF GAP AGD13, Protein ARF-GAP DOMAIN 13, AtAGD13.
Protein: MURQ_BRUA4
Sequence: MTEQALLSELDRLVSEERNPRTMDIDLLSSLAIVRRINDEDHLVPAAVEQVLPQVAQAVDKVVDAFRVGGRLIYLGAGTSGRLGVLDASECPPTFSVPEGMVIGLIAGGVDALQHAIEGAEDDPSLGESDLRNIGLTSHDVVVGIAVSGRTPYVIGGLAYAESIGATTVALSCNPDSTIATMAEIAISPVVGPEILTGSTRLKSGTAQKLVLNMLTTASMIRIGKTYENLMVDVSATNNKLVARASRIVMQATGCGAGEAKRVLALTDNEVKLAILITITGMPVDEARKALKNAGGFLRQAINANKA
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.