PharMolix/UniProtQA huggingface dataset:
Protein: BOLA4_ARATH
Sequence: MAQTLMATTRPYVLLSSTRASLYRLFQSSKRPFASFSAPLVRFTNSRCVSAVLSRKETAPSSIYGNRVSRVSGFGALDIRSLNFSTKSSQINDAGSIDQTLMQSMELKIKEQLNAESVTVTDMSGDGRHVCINVVSSAFEGQSAVNRQRMVYKAIWEELQNVVHAVDQMTTKTPSEV
What is the function of this protein?
May act either alone or in interaction with glutaredoxin as a redox-regulated transcriptional regulator, or as a factor regulating Fe-S cluster biogenesis.
What are the official names of this protein?
Protein BOLA4, chloroplastic/mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bolA/yrbA family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: TC108_PHYPA
Sequence: MAELEKLAAARLEKEASNNTVNPVREVSEDDVKDVSGETTVVTTSISEGANESLSKKEDEPALIGSNVPEELEGNSLEVQSAITTDLEKVSSTPTPSNAEKESPEATEVRIVEEGKLEKADPSVVNEELSKEILEDPEVVPSPAKMYTALKAVDGDMPVLKSENGNDGDTDANTADEDNENDEDDVDEDEDEDDADMDTAKALAELAMTAGKSGNPAFSGTKPSMGAAGPSLPSLPQRPAVRKPIAATASDSPGRNTQRPNGALSTQITSTTDESASSDAAEGDETREKLQNIRVKFLRLAHRLGQSPQNVVVAQVLYRLGLAESLRGGSAPNRSGAFSFDRANALAEEQEAANQEEELDFACTILVLGKTGVGKSSTINSIFDERKSVTSAFKPSTNKVQEVIGTVHGIKVRVIDTPGLLPSVADQQHNERIMGQVKKYIKKASPDIVLYFDRLDMQSRDFGDLPLLRTITDLFGAAVWFNAIVVLTHASSAPPDGPNGVPLSYEMFVAQRSHVVQQTIRQAAGDMRLMNPVSLVENHPACRTNRTGQRVLPNGQIWKPQLLLLCFASKILAEANSLLKLQETTAPGRPFGQRSRVPPLPFLLSSLLQSRAQLKLPDEQAGESDESDDDEEEEDSDADDYDELPPFRPLSKEELEDLTKEQREDYMEELADRERMFQKKQYREEIRRRKEAKKRQAQMSKEELAEAEEAEDEAGNAAAVPVPMPDMALPPSFDSDNPTHRYRYLETANQWLVRPVLETHGWDHDAGYDGFNVEKMFVVKEKIPASVSGQVTKDKKEAQVNFEAAASLRHGEGKVTLTGFDVQTIGKDLAYTVRAETRFNNFKRNKTTAGVTATYLNDTIAAGVKLEDRVLIGKRVKLVVNGGVLTGKGDKAYGGSLEATLRGKEYPLSRTLSTLGLSVMDWHGDLAIGGNLQSQFMVGKTMMVGRANLNNRGSGQVSIRASSSEQLQMVLIGIVPILRSLINCRFGFGGQSQQ
What is the function of this protein?
GTPase involved in protein precursor import into chloroplasts.  Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis.  Probably specialized in the import of nuclear encoded non-photosynthetic preproteins from the cytoplasm to the chloroplast.
What are the official names of this protein?
Translocase of chloroplast 108, chloroplastic, 108 kDa chloroplast outer envelope protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC159 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Single-pass membrane protein.
Protein: MINC_SHIBS
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLKHAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGKEKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARLQLVENALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: XYLA_YERPS
Sequence: MQSYFNELEQVRYEGSQSTNPLAFHHYNPDEMILGKRMADHLRFAACYWHTFCWGGADMFGANAFDRPWQQPGDALALAKRKAEVAFEFFHKLNVPYYCFHDVDVSPEGASLQEYLNNFAVMTDVLAEKQAASGVKLLWGTANCFTHPRYGAGAATNPDPEVFSWAATQVFTAMNATRQLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDPQLGWDTDQFPNSVEENTLVMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKFAAKMIEDGQLDQIVAKRYAGWNSELGQQILQGKMSLEELSRYASQHNLNPQHQSGHQELLENKVNRYLFG
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_METM7
Sequence: MSFQEVWEKEPMKKPRIQKVTVNFGVGEAGDRLTIGAKVIEELTGQSPVRTLAKQTNPAFGIRKKLPIGLKVTLRGKNAEEFLGNAFSAFKTCGKVLYASSFDQVGNFSFGVPEHIDFPGQKYDPSIGIYGMDICVTFEKSGYRVKSRKVKRSHIPKKHLVTKDEAIEYIQAKFDTEVVRE
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ENGB_METJA
Sequence: MCETMDFFERYKNLKEKYEEKKTKPKVIVVGRSNVGKSTFVRLMTGRKDIRVGKKPGVTLKINEYDMGEYILVDMPGFGYMAGLPKKVQEKIKDEIVHYIEEHADEIAAAVQIIDTKSFFEIVERWKGRGEIPIDLEMFDFITDLKISPILVANKMDKIKKEEWDAVLDGICEYLKCQPPWHQWKFIVPAILKEGKGIEEIKKKILERVRLFKKLRGIE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: Y2996_MYCBO
Sequence: MTGESGAAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRAIAASGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPAPPVGKYVDAWGGMIQSRGEGHARSIGVSNFTAEHIENLIDLTFVTPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLALGRLLDNPTVTSIASEYVKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRVREDPLTYAGT
What are the official names of this protein?
Uncharacterized oxidoreductase Mb2996.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: ARGD2_BORPE
Sequence: MEFSQFKVNALMEITARPDLVFVRGQGSWLEDHAGKRYLDFVQGWAVNTLGHCAPEMKRAMAEQADKLMNPSPAFYNLPSIELAQRLTSASCFDRVFFANSGAEANEGAIKLARKWGRVNRNGAYKIITMNHGFHGRTLATMSASGKPGWDTMFAPQVEGFPKAEINDLDSVRALIDAQTVAVMLEPVQGEAGVIPATREFMQGLRKLADEHGILFIVDEVQTGMGRTGSLFAYQQFDVIPDIMTLAKGIGGGIPLAALLAREEVCVFAHGDQGGTYNGNPLCAAVGVAVFDTITAPGFMEAAQARTRQLSEGLLALSAKWSLRGERGMGLLRALVLDRDDAPAIVEAARMLAPEGLLLNAPRGNLLRFMPALNVTEADMARMLEQLDGVIAAVRK
What are the official names of this protein?
Acetylornithine aminotransferase 2, ACOAT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_YERPS
Sequence: MNVIEGVVATPNARVAIAIARFNNFINDSLLDGAIDALKRIGQVSDDNITVVWVPGAYELPLVANVLAKTNRYDAVIALGTVIRGGTAHFEYVAGEASSGLSSVAMNSDIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVIKAIKG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: GLNA_LUPLU
Sequence: MSVLSDLINLNLSDTTEKIIAEYIWVGGSGVDLRSKARTLSGPVNDPSKLPKWNYDGSSTGQAPGKDSEVILWPQAIFKDPFRRGNNILVMCDTYTPAGEPIPTNKRHAAAKIFSHPDVVAEEPWFGIEQEYTLLQKDIHWPIGWPLGGFPGPQGPYYCGTGAEKAFGRDIVDSHYKACLYAGINISGINAEVMPGQWEFQVGPSVGISAGDELWVARYILERITEIAGVVLSLDPKPIPGDWNGAGAHTNYSTKSMRNDGGYEVIKKAIEKLGKRHNEHIAAYGEGNERRLTGRHETADISTFFWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYVVTSMIAETTLL
What are the official names of this protein?
Glutamine synthetase nodule isozyme, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC184_BOVIN
Sequence: MEEGLLEIMTKDGGDMPAPLEVSTVPAVGDVISGEYNGGMKELMEHLKAQLQALFEDVRAMRGALDEQASHIQVLSDDVCANQRAIVSMCQIMTTAPRQGGLGVVGNKGNFPGARRDPETPSPGIGDSGLLGRDPEDEEDDDEEEKEMPSSATPTSHCELPESPCAGLLGGDGPLVEPLDLPDITLLQLEGEASL
What are the official names of this protein?
Coiled-coil domain-containing protein 184.
Protein: WLS_DROME
Sequence: MSGTILENLSGRKLSILVATLLLCQVLCFLLGGLYAPLPAGHVTVLGSLCREDHARQNDTSFLLYSRGAGACIPVTREEVEQDSTKMANELVHVFQMPLPRDLRDLDYSRWQQNLIGVLQVEFGYDSSSELREPPRELQLTIDMRLAYRNKGDPDNGWKLYAHGVEHRYLDCVTSHVGPTETLYSCDMIPLFELGALHHSFYLLNLRFPLDTPSQMNLQFGHMHDLTLTAIHQNGGFTQIWLLLKTMLFPFVVGIMIWFWRRVHLLQRSPALLEYMLIYLGAALTFLNLPLEYLSLVYEMPYMLLLSDIRQGIFYAMLLTFWLVFAGEHMLIQDAPNKSTIRSRYWKHLSAVVVGCISLFVFDICERGVQLRNPFYSIWTTPLGAKVAMTFIVLAGVSAAIYFLFLCYMIWKVFRNIGDKRTSLPSMSQARRLHYEVPLDQKVEDWAGIVYFYTKAFFFQLHKANESKGLIYRFKFLMLATLVCAALTVAGFIMGQMAEGQWDWNDNVAIQPTSAFLTGVYGMWNIYIFALLILYAPSHKQWPTMHHSDETTQSNENIVASAASEEIEFSHLPSDSNPSEISSLTSFTRKVAFD
What is the function of this protein?
A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells.  In non-neuronal cells wls directs wg secretion.  The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26).  In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles.  Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip.
What are the official names of this protein?
Protein wntless, Evenness interrupted, Sprinter.
What is the protein family that this protein belongs to?
Belongs to the wntless family.
What are the subcellular locations of this protein?
Presynaptic cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=In non-neuronal cells, wls binds to wg in the Golgi and accompanies it to the plasma membrane where the two proteins dissociate. Wg is secreted and wls is then internalized and returns to the Golgi apparatus in a retromer-dependent manner. Wls and wg colocalize in the Golgi apparatus in wg-producing cells, and reduced expression is seen in non-producing cells. Endoplasmic reticulum expression is unchanged in wg-producing versus non-producing cells. In neuronal cells, wls is localized both pre- and postsynaptically and is transferred trans-synaptically from the pre- to the postsynaptic compartment.
Protein: MURB_ALKMQ
Sequence: MDKENLYQEFVALMGEEHVFLEEPMKKHTSFKIGGPADLLVMPRTVEEIRQSVEICKKSKTPYFVMGNGSNLLVRDKGMRCVVIKIAENFNEVRFEGNHVIVQTGILLSTLSNQIARACLKGFEFANGIPGTVGGAITMNAGAYGGEMKDVVKSCKVLNHQGEIIDLSLEELELDYRTSIIQEKGYIALEVVLALQEGKYEEIRSIIDDLTVKRTTKQPLHLPCAGSVFKRPPGYFAGKLIQDCNLKGFKIGGAQVSELHSGFIVNIDNASAADVLNLIAHIQKQVKEKFDVGLHNEVRVVGEV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_RHILW
Sequence: MPESRTSADGGMETSYGFREVPGGEKQDLVNQVFHKVAKRYDIMNDVMSMGMHRAWKDAMISALNPRKEPGYRVLDVAGGTGDIAFRIVEASGRQAHATVLDINGSMLGVGAERAEKKKLSGNLTFVEANAEELPFEPASFDAYTIAFGIRNVPRIDAALSEAYRVLKRGGRLLVLEFSEVDMPLLDRIYDAWSFNAIPQFGKAITGDAEPYQYLVESIRKFPNQENFAAMIRQAGFSRVTYTNYTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: FUS_NPVAC
Sequence: MVSAIVLYVLLAAAAHSAFAAEHCNAQMKTGPYKIKNLDITPPKETLQKDVEITIVETDYNENVIIGYKGYYQAYAYNGGSLDPNTRVEETMKTLNVGKEDLLMWSIRQQCEVGEELIDRWGSDSDDCFRDNEGRGQWVKGKELVKRQNNNHFAHHTCNKSWRCGISTSKMYSRLECQDDTDECQVYILDAEGNPINVTVDTVLHRDGVSMILKQKSTFTTRQIKAACLLIKDDKNNPESVTREHCLIDNDIYDLSKNTWNCKFNRCIKRKVEHRVKKRPPTWRHNVRAKYTEGDTATKGDLMHIQEELMYENDLLKMNIELMHAHINKLNNMLHDLIVSVAKVDERLIGNLMNNSVSSTFLSDDTFLLMPCTNPPAHTSNCYNNSIYKEGRWVANTDSSQCIDFSNYKELAIDDDVEFWIPTIGNTTYHDSWKDASGWSFIAQQKSNLITTMENTKFGGVGTSLSDITSMAEGELAAKLTSFMFGHVVNFVIILIVILFLYCMIRNRNRQY
What is the function of this protein?
Class III viral fusion protein.  Envelope phosphoglycoprotein which mediates the fusion of viral and host endosomal membranes leading to virus entry into the host cell.  After receptor-mediated internalization of the virus, gp64 undergoes conformational change into a fusion-competent state at low pH, and the nucleocapsid is released into the cytoplasm after cell fusion.  May also play role in budding.
What are the official names of this protein?
Major envelope glycoprotein, gp64.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae gp64 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: PHE2_ARATH
Sequence: MKRKMKLSLIENSVSRKTTFTKRKKGMTKKLTELVTLCGVEACAVVYSPFNSIPEAWPSREGVEDVVSKFMELSVLDRTKKMVDQETFISQRIAKEKEQLQKLRDENHNSQIRELMFGCLKGETNVYNLDGRDLQDLSLYIDKYLNGLTRRIEILIENGESSSSLPLPIVANAAAPVGFDGPMFQYHNQNQQKPVQFQYQALYDFYDQIPKKIHGFNMNMNKDSNQSMVLDLNQNLNDGEDEGIPCMDNNNYHPEIDCLATVTTAPTDVCAPNITNDL
What is the function of this protein?
Probable transcription factor involved in the development of gametophytes and seeds.
What are the official names of this protein?
MADS-box transcription factor PHERES 2, Agamous-like MADS-box protein AGL38.
What are the subcellular locations of this protein?
Nucleus.
Protein: NEMP1_PONAB
Sequence: MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAEIDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVNSSKLVRVTQVENEQKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMSVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYILTVGFMSFAVCYKYGPLENERSIDLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEYPIQWLYITYRKVCKAAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT
What is the function of this protein?
Together with EMD, contributes to nuclear envelope stiffness in germ cells (By similarity).  Required for female fertility (By similarity).
What are the official names of this protein?
Nuclear envelope integral membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the NEMP family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein; Nucleoplasmic side. Nucleus envelope. Note=Colocalizes with lamins and RAN-GTP at the nuclear envelope.
Protein: RHOV_BOVIN
Sequence: MPPRELSEAESSPLRSPTPPPGRGSASPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDLDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
What is the function of this protein?
Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway.
What are the official names of this protein?
Rho-related GTP-binding protein RhoV.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endosome membrane; Lipid- anchor; Cytoplasmic side. Note=Treatment with TNF activates endosomal but not plasma membrane RHOV.
Protein: ISPG_TREPA
Sequence: MDSSAGVSPCNSPYGSGLLDVPLKLRPRASHYRARSLVIGGKEHVRALPLGGDAPIPIQTMWKEPLIGADLQSIVDRLLELEQLGCDVVRFAVPDRESAELFVALCARTRMPLVADIHFDYRLALRCMDGPVAKVRINPGNIGVRERVRAVVEKARATGTALRIGVNTGSLPGVVKRAVAARYADGMQSVNARAEALVQTAFAEAAYLDQLHFDRVVLSLKASTVAETVRANELFAQQSDIPLHLGVTEAGPLVSGIVKSTLAFSQLLSRNIGATVRVSLSDSMEHEVLAAREILAECGKRAGGVRLVSCPRCGRIGFDVHAFVRRWQKELFSLKKDITVAVMGCVVNGPGEGKHADLGISGAEDSVIFFKRGKIVRRIQVRDLCADERTRIIDAAFKEELSSL
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: MCM3_BOVIN
Sequence: MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLSNAFEELVAFQRALKDFVASIDATYAKQYEEFYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTSLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQIITIQEMPEKAPAGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDVQPSFSAEDIAKIKKFSKTRSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSPDDQQDTQIYEKHDNLLHGIKKKKEKMVSAAFMRKYIHVAKIIKPVLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESDAEDEVEKSQEDQEQKTKRRRICPSDAKEGDSYDPYDFTNTEEEMPQVHTPKATDSQETKESQKVELSESRLKAFKAALLEVFREAHAQSVGMNRLTESVNRDNEEPFSSAEIQAALSRMQDDNQVMVSEGIVFLI
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.  Required for the entry in S phase and for cell division.
What are the official names of this protein?
DNA replication licensing factor MCM3.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses.
Protein: VATE_THEAC
Sequence: MSLEEVLKDIERDKEEKKKEIADAASRETAKIEKEREEKIQILQREYENRMREEGSRLYNSIIDKANVEARNIVRMRVQEILDQYGAKADELIKNLAKTKEYDDVLKKMIEVSRKALGPDCIVKVNTADKGRISDGNIKFEDIDPYGGVLATSRDGKIELDLRISSIRRDILERFKVRLYSMIED
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: LVHK2_ERYLH
Sequence: MAVGLAEHDKEAWGRLPFSLTIADISQDDEPLIYVNRAFEQMTGYSRSSVVGRNCRFLQGEKTDPGAVERLAKAIRNCEEVEETIYNYRADGEGFWNHLLMGPLEDQDEKCRYFVGIQVDMGQSESPDRATELDRQLAEVQHRVKNHLAMIVSMIRIQSSQAGGVGSQFDSLSRRVEALQLLYQEMDIAGAAKATDKIIPLGAYLGRIASAINHIDGRGAIKVNVQADTVDVPVETAGRIGLLVSEVLTNALQHAFSDRASGVVQLRSSVMSGEQLRVTVEDDGRGIPEDCDWPNEGNLGSRIVRQLVQGLGAELNVTRGGTGTIVNIDIPLSQQKTLIADERTKD
What is the function of this protein?
Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light.
What are the official names of this protein?
Blue-light-activated histidine kinase 2, EL346-LOV-histidine kinase, EL346-LOV-HK.
Protein: LKHA4_RAT
Sequence: MPEVADTCSLASPASVCRTQHLHLRCSVDFARRALTGTAALTVQSQEDNLRSLTLDTKDLTIEKVVINGQEVKYTLGESQGYKGSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRKIYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFHALGGWGELQNTIKTFGESHPFTKLVVDLKDVDPDVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVEKFSYQSVTTDDWKSFLYAHFKDKVDLLNQVDWNAWLYAPGLPPVKPNYDVTLTNACIALSQRWVTAKEEDLNSFSIEDLKDLSSHQLNEFLAQVLQKAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKACMHPVTAMLVGKDLKVD
What is the function of this protein?
Bifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities (By similarity).  Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the pro-inflammatory mediator leukotriene B4 (LTB4) (PubMed:1544505).  Has also aminopeptidase activity, with high affinity for N-terminal arginines of various synthetic tripeptides.  In addition to its pro-inflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL).  Involved also in the biosynthesis of resolvin E1 and 18S-resolvin E1 from eicosapentaenoic acid, two lipid mediators that show potent anti-inflammatory and pro-resolving actions (By similarity).
What are the official names of this protein?
Leukotriene A-4 hydrolase, LTA-4 hydrolase, Leukotriene A(4) hydrolase, Tripeptide aminopeptidase LTA4H.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHL1_LOTJA
Sequence: MNNHHQQLNPQFDPTSHDDFLEQMLSTLPSFWDPNSDLSAETTPDNVAAFPFDEHSTLNSKFRNHQITSPTTKAAAALMLQQHLLQMPANDVVDPTNFFKSPNPGGEASASVQALYNGFTGSLNGTQPQQHFQHPPQGNSNQIQGQNFGATNQAPPASGSAGGGGNQGQAKPRVRARRGQATDPHSIAERLRRERIAERMKALQELVPNANKTDKASMLDEIIDYVKFLQLQVKVLSMSRLGGAAAVAPLVADISSEGGGGGGGGDCVTNGAGGVLPRSTTTAASTTNDSLTMTEHQVAKLMEEDMGSAMQYLQGKGLCLMPISLATAISTATCHTRSPLIPNNLANLAAAAASNGEGPSSPNMSVLTVQSAVAGNDSTVKDVSKP
What is the function of this protein?
Transcription factor that regulates the development of root hairs.
What are the official names of this protein?
bHLH transcription factor RHL1, Basic helix-loop-helix protein RHL1, Protein ROOT HAIRLESS 1, LjRHL1.
What are the subcellular locations of this protein?
Nucleus.
Protein: EMAL2_HUMAN
Sequence: MSSFGAGKTKEVIFSVEDGSVKMFLRGRPVPMMIPDELAPTYSLDTRSELPSCRLKLEWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAIHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHMLSVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHIYFWTLEGGSLSKRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQAVLGAHDGGVFGLCALRDGTLVSGGGRDRRVVLWGSDYSKLQEVEVPEDFGPVRTVAEGHGDTLYVGTTRNSILQGSVHTGFSLLVQGHVEELWGLATHPSRAQFVTCGQDKLVHLWSSDSHQPLWSRIIEDPARSAGFHPSGSVLAVGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDPATCKQITSADAVRNMEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV
What is the function of this protein?
Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules.
What are the official names of this protein?
Echinoderm microtubule-associated protein-like 2, EMAP-2, HuEMAP-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EMAP family.