PharMolix/UniProtQA huggingface dataset:
Protein: LEUC_MYCA9
Sequence: MTSVQQPRTLAEKVWDSHVVVRGTGEGEAREPDLIYIDLHLVHEVTSPQAFDGLRLAGRQVRRPDLTIATEDHNVPTIDIDKPIADPVSRTQVETLRKNCEEFGIRLHPMGDAEQGIVHVVGPQLGLTQPGTTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFRTMAINIDGSLPTGVTSKDVILAVIAKIGTGGGQGYVLEYRGQAVEEMSMEARMTMCNMSIEAGARAGMVAPDETTYAYLKDRPHAPKGQLWDAAVAEWDSLRTDEGAQFDAEVHIDASTLTPFVTWGTNPGQGVPLGADVPDPELMADEEERLAAEKALTYMDLTPGTPMREIPVDTVFVGSCTNGRIEDLRAVADVLRDRKVAAGVTMLIVPGSMRVRAQAESEGLGEIFAAAGAQWRQAGCSMCLGMNPDQLSPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGKLSSPADLAKSVK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: ARGB_LEUCK
Sequence: MTKKIIIKIGGSAAEQLTPAFFDTIKYWQTQDTQIAIVHGGGDRISQLMSQLHEPIEKINGIRLTTQTGINITKMALLGQVQPALIEACRQQGIATIGLNAGSNQLLTGHLLDSDTYGYVGAIHQVNTQLIHQLWQQKLIPIIAPLAITNDGQWLNVNADHAATAIAKYLKADELYLLTDVSGVAVSGNILQELTPGKAKQLQDDHIITGGMIPKINSALHAVKRGVHNVHITDTVTHPGTIVTL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPB_YERPN
Sequence: MRNYDLSPLLRQWIGFDKLASTMQGGQEPQGFPPYNIEKTDDNHYRISLALAGFKQSELDIEVEGPRLTVRGKPTPVEKQVEYLHQGLVRKEFSLTFTLAEHLNVDNAQFENGLLHIDLLRQVPEALQPQRIAIGSATPQERQVLESPEAPDQQ
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SL_DEIAC
Sequence: MGRFIFVSFGLLVVFLSLSGTAADCPSGWSSYDGHCYQVFSDLKNWDDAESFCSGQHEGSRLASIHSREEEAFVGKMASRTLKYTSMWLGLNNPWKECKWEWSDDTRLDYKVWTRRPYCTVMVVKTDRIFWFNRGCEKSVSFVCKFKAYSEDAAE
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec clone 2100755, C-type lectin clone 2100755.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXA_ERYLH
Sequence: MGEPQRPLAVSLGDPAGIGPEIIVHAWRMRDSANLAPFAVAGGANVLRSATEALGVPCPIQEIDDIAEANSAFLEALPVIKGLDGAYLPGAPDPIGAKLALKSLEMATRLATAGHASGVVTAPIAKGLLEQVGFTHPGQTEFLAAACGLPEDASVMMLAGPSLRAVPLTVHCPLAEVPGLLSIGLIVERGRIVASALQRDFGIERPRLAVTGLNPHAGEDGKFGNEEQDVIAPAIAELLADGITATGPHPADALFSPHSRAGFDAALCMYHDQALIPVKALDFDQGVNVTLGLPIVRTSPDHGTAFDIAGRGTAHPGAMVFALLMAGECAARRADA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLDH_CHLTR
Sequence: MNEAFDCVVIGAGPGGYVAAITAAQAGLKTALIEKREAGGTCLNRGCIPSKALLAGAEVVTQIRHADQFGIHVEGFSINYPAMVQRKDSVVRSIRDGLNGLIRSNKITVFSGRGSLISSTEVKILGENPSVIKAHSIILATGSEPRAFPGIPFSAESPRILCSTGVLNLKEIPQKMAIIGGGVIGCEFASLFHTLGSEVSVIEASSQILALNNPDISKTMFDKFTRQGLRFVLEASVSNIEDIGDRVRLTINGNVEEYDYVLVSIGRRLNTENIGLDKAGVICDERGVIPTDATMRTNVPNIYAIGDITGKWQLAHVASHQGIIAARNIAGHKEEIDYSAVPSVIFTFPEVASVGLSPTAAQQQKIPVKVTKFPFRAIGKAVAMGEADGFAAIISHETTQQILGAYVIGPHASSLISEITLAVRNELTLPCIYETIHAHPTLAEVWAESALLAVDTPLHMPPAKK
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of 2-oxoglutarate dehydrogenase complex.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_DESHY
Sequence: MGVAQHRQSKSRVRKRRAMWKLTAPNHIECPQCHKPKMPHHVCPSCGYYKAKEVISMGE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CHED1_ALBFT
Sequence: MNMFASGTAALPLRASGVVVAPTVLAGGALSRVDQLKAQIRNPGEASFFYRDHHFQYDAVKVLPGEYFVSAEDLVIMTVLGSCISACIWDGRVRAGGMNHFMLPDGDSVDGFGRYGSYAMELLINELLKKGARRESMQAKVFGGAAVMAGFTTMNVGERNTKFVLDYLATERIPVVSQDVLDIHPRKVCFFPVTGKVLVKRLAHSHPETLAVEERKGNAATVAKATSGGSVDLF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD 1.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: DEOD2_VIBCH
Sequence: MATPHINAQPGDFAETVLMPGDPLRAKYIAETFLEDVKQVCDVRSMFGFTGTYKGKKVSVMGHGMGIPSCSIYVHELIAEYGVKNIIRIGSCGAVRDDVKLMDVVIGMGASTDSKVNRIRFSGHDFAAIADYDLLETAVNQARAQQVPVKVGNVFSADLFYTPEPEIFEKMKKLGILGVDMEAAGIYGVAADLGARALTILTVSDHILRGEKLSSEDRQKSFNDMMKVALETAINI
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type 2, PNP 2.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: FOLD_ACIF5
Sequence: MTARRIDGKAIAQKIHADISLRSHAFLRQWGRSPGLAVVLVGADPASRIYVQKKRETCASVGIASFSANLPADTNPQQLLAHIGELNVNDAVDGILVQLPLPPHFDPEEIIEAIAVEKDVDGFHPYNIGRLALRAPLLRSCTPAGIMTLLQESGIDIKGKEAVIVGASNIVGRPMALELLLAGATVTVCHRFTRDLAAHVGRAELLVAAAGKPGLISGAWIREGAVVIDVGINRLPDGRVTGDVDFAGAEQRAAWITPVPGGVGPMTVATLLQNTLIAAEHRMGAPHV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HUTG_PARPJ
Sequence: MRVPFDDKMWAGRSDDGEPGDTRRVFNQIVPFDGSLRAHGDTTVVVGFGSDEGVRRNQGRTGAAHAPKELRRALAGLPAKNSMAMLADAGDVACDDGDLEGAQAELANVISEVLASGGRPLVFGGGHEVAWATYCGLVLHQHRREADESATPRKLLIINFDAHFDLRQKRPANSGTPFDQIANDCAERRVPFNYVCFGISDLGNTASLFVHAQRLGVRYALDVDMQETQLPLRLQELDLMLDEADDVYLTIDLDVLPAATAPGVSAPAALGVPLFVVEEMVRRVRGSGKLRAADIAEYNPSLDQDRRTARAAARLAYRLL
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: DSBB2_PSEU2
Sequence: MYLARTRFLFFLASLACASIIGVAFYLQQAVGLDPCTLCMVQRAAFIACGVLALCAACHAPGPTGTRRYSLGLLLVALAGLAGAGTQVWLQTASADQLIPFITRLEQILSLLSLDMCIDRLRSDALFCAEITWTLFGISLPEWSLLAFTGLALLPLYPLFSELSHWLATRDRGGY
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B 2, Disulfide oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRM1_ENCCU
Sequence: MESKDGARETISEESTVITKNEWTFFNPAQKFNRDISIEVVKECFKDRASIRVLDAMSATGLRGIRYLKEIGNSIVYLNDISQSSVDTIRSNVLLNGIEDAEYFGSDLQGIKESGNARANVVKSDCNVLMTSLPCFFDVIDIDPFGSCSEYIDSALRAIRHKGILCLTATDKGVLCSNERKCLIKYSTSIMKGMGMNEVPLRTIVSLVSRQASKFDCSVEPVMSLSIDFYVRIFLRIVRRNPRSVVERNSHVLMCVCHNLAEIRSGQREIDSRCSNCSRRMRLCGPFWNGPLHDVKVIQGVLGGMNGGNKRLLGILRYLEQEIPTMFYYEIPRLCSLLGISTIKQSRLMHALANMGYQVSYTHSELNAIKTNAPIASINKVLILSGAGDQERMEELGVEFNGNEGVKALESIEFFKGLLKSGMGPLPLPRKH
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: RUVB1_USTMA
Sequence: MATANTSSGSMNGVGPVTMDSSTSGASREARIATHSHIKGLGLSDDGTALPSAQGFVGQKAAREACGLVLDLIRMKKFAGKALLLAGGPGTGKTALALAVSQELGHKVPFCPMVGSEVYSSEVKKTEVLMENFRRAIGLRVRETKEVYEGEITELTPTEAENPLSGYGKTIAHVVIALKTVKGTKQLRLDPSIYESIMKERISVGDVIYIEANTGAVKRVGRSDAYATEFDLEAEEYVPLPKGEVHKRKEVVQDVTLHDLDMANAKPQGGQDIMSVVGQLVKGRRTEVTDKLRGEINRVVDKYIEQGIAELVPGVLFIDEVHMLDMECFTYLNRALESTISPHVILATNRGQCMVRGTEYEGPASGTGIVAPHGIPLDLLDRCMIVRTMPYEKDEIREVLRLRAKVEGHLIAEDALEKLTEEGVSSSLRFALQLLSPSSILAKTAGRSEITIKDIVEANELFIDARRSAKVLMSIGEATTEAVPMETS
What is the function of this protein?
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.  The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair.  Also involved in pre-rRNA processing (By similarity).
What are the official names of this protein?
RuvB-like helicase 1.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTS_THEVB
Sequence: MAEISAKLVKELRDKTGAGMMDCKKALQESNGDMEAAITWLRQKGLASAGKKAGRVTSEGLVDSYIHTGGRIGVLVEVNCETDFVARNEKFKTLVQDIAKQIAACPNVEFVSLDDIPAEYKEKERQIALGSDALKGKPPEVQEKIVAGKLEKTLKELCLLYQPFIRDQSKTVEELVKEHIAELGENIRIRRFQRFVLGEGIEKQETNLAEEVAAQTQAMRAAAQTAAAAETAPPEVSEPEPAAAVTAEEPTPEPVAAAEQPAEPVSELVEQPGAESKGFGAATKKSGGKSRSNKKKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_STAAW
Sequence: MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDAADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNSMLHGGYSNEQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P_PIG
Sequence: MRLENREGRPTSGVLEMELPQASAPSRAGLGSLGLVGLDSSNHRPQQGGSKAGSRGPYLSGAAGQSCWVPMDQDFGPFLTERRSHCPFPKHFSSRSKDPCFTENTPLLGSFSQEEGSRCIPVYRPEFITADEPWENSSAEWEGGALLSTELAVSSGSASTEKGELLDSAHIRCHLSKLRCCVQWLKVSGLFVFVVLCSILFSLYPDQGKFWQLLAVSPLESYSVNLSSHADSMLLQVDLAGALVASGPSHLGKEEHVAVEVTQANAPGSRRRRPQQVTHNWTIFLNPSGGEHTVMSRTFEVLSREPVSINIRASLQQTQIVPLLMAHQYLRASIEAQVTIAAVILAGVYVLIIFEIVHRTLAAMLGSLAALAALAVIGDRPTLTQVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYQLSRGRVWAMIIMLCLIAAVLSAFLDNVTTALLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFAGICFVLLFSFPLLRLLYWNRKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLSLERLLARRLHSFHRQISQEDKNWETNIQELQKKHRISDRTLLTKCVTVLGLVIFMFFLNSFVPGVHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFILMEALAHLHLIEYVGEQTALLIKMVPEDQRLAAAIIVVVWVSAIASSLIDNIPFTATMIPVLLNLSRDPEISLPAPPLMYALALGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMVVSCMVGMCYLLVAHVVMGWN
What is the function of this protein?
Contributes to a melanosome-specific anion (chloride) current that modulates melanosomal pH for optimal tyrosinase activity required for melanogenesis and the melanosome maturation.  One of the components of the mammalian pigmentary system.  May serve as a key control point at which ethnic skin color variation is determined.  Major determinant of brown and/or blue eye color (By similarity).  Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis (By similarity).
What are the official names of this protein?
P protein, Melanocyte-specific transporter protein, Pink-eyed dilution protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Melanosome membrane; Multi-pass membrane protein.
Protein: RL19_SORC5
Sequence: MQTSNILAKIEAPLFREGIPDFRVGDTVRVHYRIVEGEKERIQVFQGVVLKRHRAGVRSTFTVRKVSFTVGVERMFLLHSPRIDKVEIVSRGVVRRSRLFYLRNLAGKAARVRDAKD
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: NGFV_DABRR
Sequence: HPVHNQGEFSVCDSVSVWVANKTTATDMRGNVVTVMVDVNLNNNVYKQYFFETKCKNPNPVPSGCRGIDAKHWNSYCTTTDTFVRALTMERNQASWRFIRINTACVCVISRKNDNFG
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor, v-NGF, vNGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: NCSB_STRCZ
Sequence: MSCRYAPDLDSPDKFWDFLVNGRSTVGDMPDKRWEPYASGSPQATAAMRDTVRRGAFLDDIEGFDAEFFGISPREADFLDPQQRFMLELAWEALADAGVPPLTLRNTDTGVYAAANSNDYGRRLLEDIPRTGAYAVNGTTLYGIANRVSYFLDLHGPSMAVDTACAGALTALHLARQSLLTGETPLAIVGGLNIMSTPSLNVALNDAGAMSPDGRSKAFDEDADGYGRGEGAGVLVLKRLSDARRDNDPVHAVIRGSGVFQDGRSDGMMAPDGDAQEHMLRQAYHRAGVDPATVDYVEAHGTGTPTGDREEITALAKVFGAGRSPHAPCLIGSVKPNVGHVEGGSGITGVIKTVLALRNELIPPTLHDRPRTDVDWDAWGVRLVGQVQEWPSCGRPRRAGVSSYGVGGTISHVILEESPVPAATSSADASTGVRTPALFPLSAASEAGLRALAGEAAGWVASRPDTPLPSVGHTLTQRRSHLAQRAAVVADSAEQLVDRLREVAEGRNGPGIVSARTSAGRADDAVWVFSGHGAQWSGMGRRLLASEPVFAATLDALDEVFREELGWTPREAVTEGGPWTAAHVQALTFAVQIGLADVWRSKGLRPGAVIGHSVGEIAAAVVAGSLDRDEAARFACRRAAALQRLDGRGAMVMVGLPFEEAALRLGDRRDVEAAISAGPHSTVLSGDRSAVLRVAEEWQASEVWTRTVDSDIAFHSVHVDEVTGDIESAARLLTPRPPTVPLYTTALSDPRSRAPRDSGYWAANLRKPVRFTEAVRAAAEDGHRLFLEVSSHPVVAHSVSETLLDLGIEDAAVAGTLRRDTDEVESLLENLAELHCHGVAVDWARHHTDGELVGLPAAVWQHRPYWIFPETTADAGLGRGHDPASHSLLGGRMTVSGSPTRQVWQTRLDMDSRPYPQSHGLVGVEVTPAASIINTFAAAVEEDGPSALTDIVLRTPLAVEPPRVVQVVREGRSLSLATRVAEDADADGSEWITHTTAAVTPGVRPAGGRLDTEAIRSRLPEGSLTRADEMFERMGVEGYAFPWDLEELRHDDHEQLAVLQIEPSPAQRATSWAHVIDGALTISAMVVSPGDATVLWMSRSIDQVTWSGEPPARLTVHSTRSLRSPHDTVDVRVADERGDVVCEVVGLRFAAVEHIGAAVLPSELVHEIVWRPWDPEDHEGAEDAPVEQVILVGDPEATVPLAEQLESAGMTCVQVGDSPETGLRPDLFARPGAVVVAPALAGSDTAPEEEAERVSWLLVRTVQRVAEIRADVTGDAPAQRVWCVTSDVRRARDERSVAHGPLWGLARIVAGDHPELWGGAVDIGPSADGIGARLVALLDGAAGTEDVISLTGEGAEVARLSRIDRSADGTPLQCSPSGTVLITGGLGALGLEVARWLVDRGARRLVLVSRRALPNRTEWPAVTDAETRRRIDGVLALEALGVTVRVLALDITDVDQVSAALAPEALGLPPVRGVVHAAGVVNNALVDKVDLEGLREVLAPKVRGAMVLHRLFPPGDLDFFVLFSSCGQFARLSGQASYAAANSFLDTLASHRNAGEHTETVSLGWTAWRGLGMSSNIDTTMFEANSRGLEAVSATEAFGAWSFGDRFQSDYQAILRVVPTPVHTPRLPVFRDLPVSGETDGPTGDQLFTTTLEGLPEQEARERITADVREQVAGVLNFDPSEVEVKRPLVELGVDSVMTVALRVRLQRRYGLELPPTILWAKPTVAALSEHVCDSLRWDGEEHGDLAAPTAAA
What is the function of this protein?
Iterative type I polyketide synthase that catalyzes the synthesis of the naphthoic acid moiety during the biosynthesis of the neocarzinostatin (NCS) chromophore.
What are the official names of this protein?
Neocarzinostatin naphthoate synthase, NNS, Naphthoic acid synthase.
Protein: QUED_PYRHO
Sequence: MTMRYIIKRKIYWTKEFDSSHFLELEYESKCKRIHGHTYKVEVEIEGELNEEGMIFDFTHLSEIVKELDHRLIVSKEWVKEVGDLVIIEKNRKILKVPRDEVVIIDKPNVTAEYLAEWFGERIAENAGSNIKKIKVRIWEDPRSYAEVTFTLEPQGS
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
What are the official names of this protein?
Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase, CPH4 synthase, Archaeosine biosynthesis protein QueD.
What is the protein family that this protein belongs to?
Belongs to the PTPS family. QueD subfamily.
Protein: VIRB9_RHIRD
Sequence: MTRKALFILACLFAAATGAEAEDTPMAGKLDPRMRYLAYNPDQVVRLSTAVGATLVVTFATNETVTSVAVSNSKDLAALPRGNYLFFKASQVLTPQPVIVLTASDSGMRRYVFSISSKTLSHLDKEQPDLYYSVQFAYPADDAAARRREAQQRAVVDRLHAEAQYQRKAEDLLDQPVTALGATDSNWHYVAQGDRSLLPLEVFDNGFTTVFHFPGNVRIPSIYTINPDGKEAVANYSVKGSDVEISSVSRGWRLRDGHTVLCIWNAAYDPVGQRPQTGTVRPDVKRVLKGAKG
What is the function of this protein?
Is essential for the biogenesis of the T-pilus, which is required for virulence and T-DNA transfer to plant cells.  When is associated with virB7, might function as a nucleation center for recruitment of VirB proteins during assembly of the T-DNA transfer machine.
What are the official names of this protein?
Protein virB9.
What is the protein family that this protein belongs to?
Belongs to the TrbG/VirB9 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FEN1_YARLI
Sequence: MGIKGLNKLLMEHCPAALRSSEIKNFGGRKVAIDASMSLYQFVIAVRQADGQQLTNENGETTSHLMGMFYRTLRMVDNGIKPVYVFDGKPPVLKSGELAKRKERREEALKKIEELKQQVEDGEEGEETKEAQEDVTRFEKRTVRVTPEQNDEAKKLLTLMGIPIVEAPCEAEAQCAKLAEAGKVYAAASEDMDTLCFGSPVLLRHLTFSEAKKMPISEINFAKILEGLEMTHAQFIDLCILLGCDYADTIRGVGPQTALKLMKEHGSLEKIVEHIEKNPSGKLKVPENWPYQEVRALLQAPDVLDSSSCDIKWNNPDVEGLVDFLVRDKGFSEDRVRAGAARLMKQVKVKPQARLDGFFKVMPKEGGEKRKADDKKTKGKKPATKKAKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: Y1688_HALSA
Sequence: MTRSVLVPSSLVREAEDKREATRKLGYVARAAAVFRIDRVVVFPDEDGERQWGGGFVETVLRYAATPPYLRKEAFDTRDELAYAGVLPPLRLSSWTGSDSSGSGSLRQGIVTQVGSEGRVRVNCGMQHPISLHEPPGMAVSEGERVTIRVSSRRPVRAKLVDDPLPGFSVERTGLGDALDRSDAGVRIATSRHGEPLSVASLGGYRERIARDGVTVAFGAPERGLPPMLGVSADAVNESVTDSSADAPARFDAWLNTIPDQGSEVVRTEEAVLATLGSLTLTE
What are the official names of this protein?
Uncharacterized protein VNG_1688C.
Protein: RL14_DESHD
Sequence: MIQVQTRLRVGDNSGAKELMCIKVLGGSMRRYASIGDIIVASVKEATPGGVVKKGDVVKAVVVRTKKEIKRKDGTYIRFSENAAVVIKDDRSPRGTRIFGPVARELRDRDFMKIISLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: KITH_HALWD
Sequence: MRAITNSGWIEVVTGSMFSGKTEELLRRLRRAEIAGQSIAVFKPAVDDRYGETTVGSHVGRQWEAAVVPNEGEDIWNIKHELSKKKQNHRTTTQCRSGDGTNNPGGVIPSNDDSVDVVAIDEANFFSTELVSVCESLANDGYRVVVSGTDQTYRGEPFEPLPQLMAVAEYVDKLQAICTQCGEPATRNQRLVDDSPAHIDDPTIVVGADETYEARCRNCHILRHE
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.