PharMolix/UniProtQA huggingface dataset:
Protein: TARI_LACP3
Sequence: MITAIVLAGGVGKRMGMEIPKQFVMVNEKPIIIYTLESFDRHPKIDQVVVVCKQGWADTMWGYIREFGIKKVKWVISGGSIVQKSINNAVQFLSDKCVEDDIVVIHDGIRPLVDEHVLSDVIVKCQEYGNAVTSLPYNEQIFIKETEKTTNKYIDRNTLRRVSTPQAYKYEVLHDAYDEAISQNIGMVDSAYTNTMMVDLGHTLYFAAGSDKNIKLTTTDDLALFKAYLREKEL
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: HIS9_DEIRA
Sequence: MTGLCDSHLHTPLCGHATGTPREYAQAALDAGLSGLCFTDHMPMPRWYDAPWRMKLEQLPEYIAEIQAVQQEFAGRLDVRLGLEADFHPGTEKFVEKVLGMFDWDYVIGSVHYLGAWGFDNPEFVAEYEERDLGGLYRDYYALVEGAARSGLFDAIGHLDLPKKFGHLDPDPVYALHALDVVAGQGLALDFNTAGWRKPVAEAYPAPDLVRAAAERGIPFVLGSDAHQPGEVGFRFADAVKEIRDVGGRTVTFRHRKMQP
What are the official names of this protein?
Probable histidinol-phosphatase, HolPase.
What is the protein family that this protein belongs to?
Belongs to the PHP hydrolase family. HisK subfamily.
Protein: RL19_THEAB
Sequence: MSMDNLVRIIEKDQIKDVPEFRPGDTVKVYVRFKEGNKERTQAFEGIVISMRGSGISKTFTVRRIGANGIGVERIFPLYAPIIEKIEVVRRGKVRRAKLYYLREVRGKVKIKERR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SC5A6_DROME
Sequence: MATLGAWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSVIICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLMAVKSLSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCFWIGFGQPKPPLVSLDMSTAGCPVDRSFARDIFLKTVIAVAEEEHYFYLYRISYMWYAALGFLITFFGGWLLSWLFALLKWDNNRRIYQDADCTLIKHDLFVPPIAKRLQRRQMPLLVVTGTSSEIGGITTESATAPPRLDEIEWEKHKAVA
What are the official names of this protein?
Putative sodium-dependent multivitamin transporter, Na(+)-dependent multivitamin transporter.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPD_ECOSE
Sequence: MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: FABH_RHOCS
Sequence: MPLRSVILGCGAYLPARVLTNEDLTRIVETSDEWIVERTGIKSRHIAADGENTSDLAEAAARAALAHAGVAAEEVDLIVLATATPDQTFPATATKVQARLGITRGAAFDVQAVCSGFVYALAIADNFIKAGQARTALVIGAETFSRILDWTDRTTCVLFGDGAGAVVLRAEEGEGTADRGILSTHLHSDGRHHDLLYVDGGPSTTQTVGHLRMKGQEVFKHAVVNLAHVVEEALAANGLSPADISWLVPHQANRRIIESTARKLKLDGSRVVLTVDHHGNTSAASIPLALCEAVHDGRVQRGDIVLLEAMGGGFTWGAALVRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOB_SHIDS
Sequence: MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSNAVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLADFLDSHDPGKTVEGYPAPKRAVLITRKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: M1_I78AF
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQVAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: CHI1_STROI
Sequence: XTSATATYAKTQDWGSCFEGKWTIKNTAACSSYPSWVAGRSYAAGDIVYYTDXGYTDLPVSRQKMCQNGMVTNC
What is the function of this protein?
Able to cleave chitin oligomers from N=3 to 6.
What are the official names of this protein?
Chitinases 70, 30, and 20.5 kDa.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
Protein: ICK3_TRILK
Sequence: MKTLVLVAVLGVASLYLLSSASEVQQLSPAEEEFRAFVSTFGGLFETEERGVDSEDCRAMFGGCGEDNDCCLHLGCKTTKLPPFANPYCAWDGTTGRK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U10-barytoxin-Tl1a, U10-BATX-Tl1a, Toxin ICK-3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 27 (ICK-3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PROP_STAA1
Sequence: MDFNKENINMVDAKKAKKTVVATGIGNAMEWFDFGVYAYTTAYIGANFFSPVENADIRQMLTFAALAIAFLLRPIGGVVFGIIGDKYGRKVVLTSTIILMAFSTLTIGLLPSYDQIGLWAPILLLLARVLQGFSTGGEYAGAMTYVAESSPDKRRNSLGSGLEIGTLSGYIAASIMIAVLTFFLTDEQMASFGWRIPFLLGLFLGLFGLYLRRKLEESPVFENDVATQPERDNINFLQIIRFYYKDIFVCFVAVVFFNVTNYMVTAYLPTYLEQVIKLDATTTSVLITCVMAIMIPLALMFGKLADKIGEKKVFLIGTGGLTLFSIIAFMLLHSQSFVVIVIGIFILGFFLSTYEATMPGSLPTMFYSHIRYRTLSVTFNISVSIFGGTTPLVATWLVTKTGDPLAPAYYLTAISVIGFLVITFLHLSTAGKSLKGSYPNVDNEQDRAYYAEHPKEALWWVKERKN
What is the function of this protein?
May be a proton symporter involved in the uptake of osmolytes such as proline and glycine betaine.
What are the official names of this protein?
Putative proline/betaine transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZWINT_BOVIN
Sequence: MGAAESEVETAAREVLAKVADIQEPVGFQEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLVQEGTAQDQNPLASEDTSRQKALEAKEQWKELKATYQEHVEVITNSLTEALPKVEEAQIKQAQLQEALKQLQAKKQMAMEKLRIAQKQWQLEQEKHLQNLAEASSEVRERQTGAQQELQRLYQELGTLKQQAGQEKDKLQRHQTFLQLLYTLQGKQLFNEAEAEIPQELDLPKDKLQQVTQPQEQNTQDTMGREADNPQPVGDAGLPWLPGRQQHKEES
What is the function of this protein?
Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity.  Required to target ZW10 to the kinetochore at prometaphase (By similarity).
What are the official names of this protein?
ZW10 interactor, ZW10-interacting protein 1, Zwint-1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase.
Protein: Y157_METAC
Sequence: MRPRKRRIVDFEHSARQFRPFGPESEIPEEVLLTIDELEVMRLSFLENLSQGEAALRMEIHQSTFQRALKKALEKVTDALVHGKAIRIEGGDYRMPRGDGTGPAGQGPVGGGRSRGQGKGRGGRFGGPDGNCVCPACGYETPHTPGVSCSQVKCEKCGSSMVRK
What are the official names of this protein?
UPF0251 protein MA_0157.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: PYRF_CAUVN
Sequence: MTADPRLIVPLDLPTVDDARAMVERLGDAVSFYKIGLELLASDGMGLAHDLKASGKSIFLDWKLHDIGATVERSARVLATSGCDLLTVHAEPQVMQAAVKARGDSSLKILAVTVLTSLTDADLVEMGYAFTARDLVERRVRQALACGVDGIVSSPHEAALAREIANDAGQPEFLIVTPGVRPEWSAKNDQARAATPADALRAGATHLVCGRPITAANDPREAALKVVTEMAGI
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: LSHB_PHOSU
Sequence: MERLQGLLLWLLLSPSVVWASRGPLRPLCRPVNATLAAENEACPVCITFSTSICAGYCPSMVRVLPAALPPVPQPVCTYHELHFASVRLPGCPPGVDPMVSFPVALSCRCGPCRLSTSDCGGPRTQPM
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAIB_SYNP6
Sequence: MSPRKTYILKLYVAGNTPNSVRALKTLKNILEVEFQGVYALKVIDVLKNPQLAEEDKILATPTLAKVLPLPVRRIIGDLSDREKVLIGLDLLYGELQDSDDF
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: UVRC_STRP6
Sequence: MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGTSPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVSLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN367_RAT
Sequence: MIRGAPAPMAEPPPVIFCHDSPKRVLVSVIRTTPATPPCSSVGEPEPPPPLVPTSPGFSDFMVYPWRWGENAHNVTLSPGAAGGVVSAGLPAATELPTLRGAPPSSASVAAVSGGEDEEEASSPDSGHLKDGIRRGRPRADTVRDLINEGEHSSSRIRCNICNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPFVCSENGCLSRFTHANRHCPKHPYARLKREEPTDTLSKHQSTDNKAAAEWLAKYWEMREQRTPTLKGKLVQKADQEQQDPLEYLQSDEEDDEKSGAQRRLQEQRERLHGALALIELANLTGAPLRQ
What is the function of this protein?
Transcriptional activator.  May be involved in transcriptional activation of erythroid genes (By similarity).
What are the official names of this protein?
Zinc finger protein 367.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBL_PINCA
Sequence: VGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYNIEPVPGETDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEEDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAAEGNAIIREASKWSPELAAACEVWKEIKFEFKAVDTLD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEUC_BACLD
Sequence: MMPRTIIEKIWDQHVIKKGEGKPDLLYIDLHLIHEVTSPQAFEGLRQKNRKVRRPQNTFATMDHNIPTVNRFEIKDDVAKRQVSALERNCEEFGIRLADLSSVDQGIVHVIGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQKPKTLEIRVDGKLQKGVTAKDVILAIIGKYGVKFGAGYVIEYTGEVFRNMSMDERMTVCNMSIEAGARAGLIAPDETTFEYVKTKKYAPKGEDFEKAVEEWKNLKTDPGAVYDRTIVMDGSAISPMVTWGINPGMVLPVDETIPGPEAFLQEDDKKEAQRAYEYMGLEPYKKIEDITIEHVFIGSCTNSRMTDLRQAAEMIKGQKVADGVRAIVVPGSQSVKIQAEKEGLHKIFIEAGFEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGRFVDVRKYYQETTAV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CAPP_BRADU
Sequence: MSLQTLPSDAADSRPNRPEDVQALEADARLRDDIRLLGRILGDTVRDQEGADLFDLVERIRQTSIRFHRDEDRLARRELEQILDSMSTSETVRIVRAFSYFSHLANIAEDQNNIRQMRARTAAKIGGSGVLADTLAHAKAAGIGPDALRNFFKTALVSPVLTAHPTEVRRKSTMDREMEVASLLDRRERVALTEDEAAASDEQLRREVLTLWQTNLLRRTKLTVLDEVANGLSFYDYTFLREVPRLVNVLEDRLEEDGDQAASELASFLRMGSWIGGDRDGNPFVTADVMRGTLRLQSSRVMQFYLNELHVLGSELSIAAHLADVSEELRTLAERSPDTSPHRSGEPYRLAVSGIYARLTATAEALEVEITRRPVGKGRPYESVKELQADLDVLHRSLISNNARVIARGRLRLLRRAVDCFGFHLARLDIRQNSAVHERTIAELMDAANPGMSYLALGEDARISLLTNELRSTRALVSPFVKYSDETMGELNVFHAAAEAHAKFGSDAIPQCIISMCKGMSDMLEVAVLLKEVGLVHPSGRSAINIVPLFETIEDLQASSAIMDRMLSLHDYRRLVDSRGSVQEVMLGYSDSNKDGGFVTSGWELYKAEINLVDVFERHHVRLRLFHGRGGSVGRGGGPSYDAIIAQPGGAVNGQIRITEQGEIISSKYSNAEVGRNNLEILAAATLEASLLHPRQSAPRREYLTAMDELSSLAFRAYRGLVYETDGFVDYFWASTVINEIATLNIGSRPASRKKTRAIEDLRAIPWVFSWAQCRLMLPGWYGFGTAVEQWIAEHPDKGMPFLKELYKEWPFFRMLLSNMDMVLAKSSIAIASRYAELVPDEALREKIFGRIRREWHSCIETLLDIMGQDRLLQGNPLLERSVRHRFPYLDPLNHVQVELLREHRAQNPDEQVLRGIQLTINGISAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: PHZA2_PSEAE
Sequence: MREYQRLKGFTDNLELRRRNRATVEHYMRMKGAERLQRHSLFVEDGCAGNWTTESGEPLVFRGHESLRRLAEWLERCFPDWEWHNVRIFETEDPNHFWVECDGRGKALVPGYPQGYCENHYIHSFELENGRIKRNREFMNPMQKLRALGIAVPQIKRDGIPT
What is the function of this protein?
Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control.  PhzA2 (operon phzA2B2C2E2F2G2) has a role in the biosynthesis of the phenazine during both planktonic growth and biofilm development, and in host infection during biofilm development.
What are the official names of this protein?
Phenazine biosynthesis protein PhzA2.
What is the protein family that this protein belongs to?
Belongs to the PhzA/PhzB family.
Protein: IML1_CRYNJ
Sequence: MEGGVLDLSLLNKDRDNVALLLYTYKPLLNNTGASANPAHPSLLPSAAASPNAPSSQVIINYAALPWNVQPGDYLEIRQINRTQPKVPTASTRIQGMEGEKPQKIKRPPALEDVKTGKGREGYVFRLGEDSPTANIHQIQVPDSVATAFGFQNRLEVEVRRIHDKESSHADYIEFYFSQYLGRADMWRLGMSLEGTTLHVGEKVSLAGGAVRAEVNFIIRDEKSKDGIAKPKRYSSGIVTAKTKTIFRSKSAQVYLFIQLCEETWQFDEDGERYVEKVVHGYLPELFARWADKGTSHVVTIIFFARIFYRDDEVDYLRKHDMVDMLSQDYSGQWYKDFFKVAVDLERRNDWMSSLPEIKRQLERSEREILLDYHLRLLKAKGAAEEEIKIVGKWCFAYQGNVLEAINLALNPFDEHYVDRDLSRTGLSITVVTPGTGHFAVDKNLLRLTTERMVDHGMSVDFVCLTKMPLHSVPLFSYVSHRPKGPVQHEDGIGAKAKPVVPDLLYFDANLSQVKDIELADCYSLPSWVSTSFYAVTHDKPFREDRFVARCKMYDIQMLGILDHNLTTVTVPLLNVDDTPMPRRPLTVDDRKAIRDSFDQSIFSGISDLVKTGSSPLDSAPASVTASYQSARLLAEKAKERTSSMSLSKPRGSDIANSSRLSPIKATSESDNIDLGKKTTPRSPSPEPSSLSLRRGSRRSLSPTKMTQLAHTSAVTNELNKDSPSLLKNSRPGSPITMARSISPVPPLPPTREQGDSPLSPVDSLPLSASVERSPSPSRRSVRSNMTDREHLGSGASTPKGTPAKSLRSQPSKGFIPSWVLNSFKPLLSTSKPSFAVPAMENVARTDVATGDDNRPSSPSPSVGSLRGRPSKGGPNPKPIITPSTPSPSRSQKPPFKPAKIIQTQPHTQAQGTQPLPIAAPPASRLPSQSEEDAISRSFRNKGHGLSRSHEDSSLRAQSNALVQSSRHFTINPCKPSAETIDRVRDAGGRRWRFVLPKLTQQHIVQWPSLIAPACLPLTTDFLPDQKQSDELYTTGTYTVQCYLEDDQFLIRSDAAETNLALAMMREMVSQRLSQNFQVIVQPHELTEPEKPRPMPIHLEKDADIGVELVSGGASEVLKKGQGAIWLSWANHIHRLLFHPTKPEIVVHWMTRKITHQTESVQWKGLVWPSGMKGYQKASATFAYPDVSMKINYNHLDHLINGERIDFAPLRYWRTRFILIPSGREPVTFPGLMPKNENLGSNDLLWLGAQKVMETLNRYLLKRPEGTPQQRSLKIVATTFDPSTCVLDEELMMDLARQIHGDSSGDKKKKLEGMTLANVAELMCQPDNGLVIRTRWWESRQHVSSFNGFELREWLQNTFEDVTGREKAQEWAAELTNKGLIEHVTKSHGFLDYWHLYYRLREPYNHMYSHLAKKEGKNKSWFSTSSKGSRAAPPSLTSSQASSSTVIAAAVADPSQATADLNTSQSGKDPSAGEQDQSSLAKIYLKVHKGEPKQGGKKRKIMMTQKRVLDLDPSRKSDRAEVAILHADVVHNARNAFHFELNWLGVTAALLEELRQKLSAQSERYGLRFVETPVEQIADIPKKCAYRTPIPIRLALAPPVIPDLHTRLVAVAHGTGQAENYFEYSILTKKFGFVLDVEATDRYPDNVEVVYSYRKAGVKYTYSQFCHKTGLALVQCVGGEAGFLWSDNRLVVSAPTRKGVGNRVDEARALRKELEDFCSDAEQLSKFYEEVLPPPPTTGESTPEEGQEEFEAKDDEEEQPAPQEKTEL
What are the official names of this protein?
Vacuolar membrane-associated protein IML1.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: U1SBP_DANRE
Sequence: MEWSPVAKVYDPLKAGSIDGTDVEPHDAGVWRAMLARYKPNRGVCGDPDLTLFVARLNPQTTEEKLRDVFSKFGDIRRLRLVRDVVTGFSKRYAFIEYKEERSLKRAWRDANKLILDQYELLVDVEQERTLPGWRPRRLGGGQGGQKESGQLRFGGRDRPFRKPINLSTRRPAEPRGRETERERDRRDYRDRRHERTHTEDRTHRHTY
What are the official names of this protein?
U11/U12 small nuclear ribonucleoprotein 35 kDa protein, U11/U12 snRNP 35 kDa protein, U1 snRNP-binding protein homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: SICA_SALTY
Sequence: MDYQNNVSEERVAEMIWDAVSEGATLKDVHGIPQDMMDGLYAHAYEFYNQGRLDEAETFFRFLCIYDFYNPDYTMGLAAVCQLKKQFQKACDLYAVAFTLLKNDYRPVFFTGQCQLLMRKAAKARQCFELVNERTEDESLRAKALVYLEALKTAETEQHSEQEKE
What is the function of this protein?
Type III secretion-associated chaperone required for SipB and SipC stabilization.  Prevents premature association of SipB with SipC, which may lead to their targeting for degradation.  Along with InvF, required for transcription activation of sigDE (sopB pipC), sicAsipBCDA, and sopE.
What are the official names of this protein?
Chaperone protein SicA, Salmonella invasin chaperone.
What is the protein family that this protein belongs to?
Belongs to the LcrH/SycD chaperone family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_SALAR
Sequence: MIIPALDLIDGVVVRLHQGDYARQRDYGNDPLPRLQDYVAQGAEVLHLVDLTGAKDPANRQISLIKTLVAGVNVPVQIGGGVRTEEDVAALLEAGVARVVVGSTAVKSPEVVKGWFERFGAQALVLALDVRIDEHGNKQVAVSGWQENSGISLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYQEVCARYPQIAFQSSGGIGDIDDIAALRGTGVHGVIVGRALLEGKFTVKEAIQCWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_THISH
Sequence: MTRIGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVIAVDRYENAPGHQVAHRAHVIPMTDASALRELVLREKPDLIVPEIEAIATDELARIEAEGIARVIPTARATQLTMNREGIRRLAAEELGLQTSRYAFADSLESLTAAIDGGIGYPCIIKPVMSSSGKGQSLVADASELTRAWDYARSAGRVDQGRVIVEAVVEFDFEITLLTVRSRGGDGNIRTDFCAPVGHRQVKGDYVESWQPQPMSETALDTAREMAAAVTGALGGQGLFGVEFFVRGDEVWFSEVSPRPHDTGLVTLATQWQSEFELHARAILGLPVDTRLRNPGASAVIYGGVEAQGVAFENVDQALAVPGTDIRLFGKPEAFERRRMGVAVAHGDDIEDCRARAREAAGRVRVVV
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: ECM_METEA
Sequence: MSAQASVAEVKRDKPWIIRTYAGHSTAAESNKLYRGNLAKGQTGLSVAFDLPTQTGYDPDHELARGEVGKVGVSIAHLGDMRALFDQIPLAQMNTSMTINATAPWLLSLYLAVAEEQGAPLAALQGTTQNDIIKEYLSRGTYVFPPAPSLRLTKDVILFTTKNVPKWNPMNVCSYHLQEAGATPVQELSYALAIAIAVLDTVRDDPDFDEASFSDVFSRISFFVNAGMRFVTEICKMRAFAELWDEIAQERYGITDAKKRIFRYGVQVNSLGLTEQQPENNVHRILIEMLAVTLSKRARARAVQLPAWNEALGLPRPWDQQWSMRMQQILAFETDLLEYDDIFDGSTVIEARVEALKEQTRAELTRIAEIGGAVTAVEAGELKRALVESNARRISAIEKGEQIVVGVNKWQQGEPSPLTAGDGAIFTVSETVEMEAETRIREWRSKRDERAVGQALADLEQAARSGANIMPPSIAAAKAGVTTGEWGQRLREVFGEYRAPTGVTLQTVTSGAAEDARLLIADLGERLGETPRLVVGKPGLDGHSNGAEQIALRARDVGFDVTYDGIRQTPTEIVAKAKERGAHVIGLSVLSGSHVPLVREVKAKLREAGLDHVPVVVGGIISTEDELVLKNMGVTAVYTPKDYELDKIMVGLAKVVERALDKRAADRADTEAGVPGAPKRNESGAQVF
What is the function of this protein?
Radical enzyme that catalyzes the transformation of (2R)-ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA (PubMed:25448820).  Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M. extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source (PubMed:8868443, PubMed:8704985, PubMed:25448820).  This enzyme acts as a regulatory metabolic control point in this pathway, that allows M. extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate (PubMed:25448820).
What are the official names of this protein?
Ethylmalonyl-CoA mutase.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA mutase family.