PharMolix/UniProtQA huggingface dataset:
Protein: RS8_ROSS1
Sequence: MHDPIADMLTRIRNACMARHATVSIPSSKMKLAIAQILKREGFIQDFTVQEGKPRNTIVITLKYTPDRRPVITGLKRVSKPGLRIYTKRADIPRVRGGLGLSILSTPRGVMAGHEAWQQRVGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MAGE1_MOUSE
Sequence: MSLVSQNSRRRRGGRANARRNNGKGHPAAVPGPDVPRDRNDPKILQGLRASEGPGTSMLPTPREGPSASVPPTASEGSSAPRQFIISQGPNTSEMPTSRKGRGASRPPAVSAGLNTAMSITASEGPNSPVPPTAPKGSKAYEHLPVSEGLAISEQRHSDGGPNMEPTLGEGPGISVPPTFSEESGISDEGLSIFMSPNISEGPGINEPYSVSEDPSTSVPPTDSNGLGINLPPTFGEGLSISMLFSALEEPDIFAPPPSAEGLFASMSPPSGEIQSSWVSPIIMEGCNVNVPPTSKKGLRTSVPSAACESPSTSAEGLSSSLSSISAEGFCSSLAPCAAEGSCELLPCGEGRSTSELHCLGEGSSTSQMSLAAEGPSASGMPTEANNPEEALSCCASERRNKSTSRALQKAKDPSVRPKREDRFLDFQVLRDSKNSNSITIMGLGTSRVALTLKPQDPMEQNVAELLQFLLLKDQTKYPIKESDMREFIDKDYRHQFPEILRRAAVHLECIFRFELKELDTEEHIYILLNKLGPVPFEGLEDVPNGPKMGLLMMILGHILLNGNQAREADIWEMLWRFGVQRERRLSVFGNVKRLLSVEFVWQRYLDYRPLTDCVPVEYEFYWGPRSRAETTKMKILKFMAKIYNKDPMDWPALYNEALEEDADRVVVNNFRVARPFRRPLFAEVAPELDASGSKYSPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECTKVFPDLLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEDTEEIMDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGLGVQNGRKHVITCRYLSQRYLDSLRVPDSDPVQYDFVWGPRARLETSKMKALRYVARIHRKEPEDWPEQYREAMEDEANRAEAGRRPLIVRNLR
What is the function of this protein?
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.  Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex (By similarity).
What are the official names of this protein?
Melanoma-associated antigen E1, Alpha-dystrobrevin-associated MAGE Protein, DAMAGE, MAGE-E1 antigen.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Cell membrane. Note=In the skeletal muscle, found at the postsynaptic membrane and is associated with a subset of myonuclei. May reside within nuclei and/or in perinuclear compartments. In peripheral nerves, colocalizes with DTNA in the Schwann cell membrane.
Protein: CYSI_STAES
Sequence: MVNTNNHISEELDKNLDEMEFLKANSDFLRGTIEQSLANPITGSITQDDAKLLKFHGSYMQDDRDLRDERRKQKLEPAYSFMIRVRVPGGKATPEQWIAMDDISNQYANHTIKLTTRQAFQFHGILKRNLKQSMKNINHAVLDSIAACGDVNRNTMCNPNPYQSQVHKEINDYATRISNHLLPRTNAYHEIWLDGEKVLDSSEEKEPIYGNTYLPRKFKIGIAVPPSNDIDVYSQDIGLIAIVEQDELIGFNVTIGGGMGMTHGITETYPQLGRLIGFIPKEKVVDVCEKILTIQRDYGNRENRKNARFKYTVDRLGETWVTEELNRRLGWEIKAPRDFEFEHNGDRLGWIEGINNWNFTLFIQNGRVKDTEDYLLKTALREIAEIHTGDFRLSPNQNLVIANVSPEKKEEIQAIIDKYKLTDGKNYTGLRRNSMACVAFPTCGLAMAESERYLPSLITKIEDLLDESGLKEEEITIRMTGCPNGCARPALAEIAFIGKAPGKYNMYLGGSFKGERLNKIYKENIDENEILESLRPLLLRYSKERLDGEHFGDFVIRDGVIAKVHDGRDFHS
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: PO5F3_CHICK
Sequence: MFSPDGGLPAAPFGLLPDGGPPFPRGGYDGAAAQQLFFPFASEPDGARDAATARAWLPPPAGPPAKAEARPARPCRQGSPEPRAAPPATPCCGPAWAAPPWPGPAPPAATAVPGPPFPGPAAAAFPAAPGHALCPAALQPSSGGLANLGSSGSSSGAASEGGHSSDSGDEDAPTSEELEQFAKDLKHKRIMLGFTQADVGLALGTLYGKMFSQTTICRFEALQLSFKNMCKLKPLLQRWLNEAENTDNMQEMCNAEQVLAQARKRKRRTSIETNVKGTLESFFRKCVKPSPQEISQIAEDLNLDKDVVRVWFCNRRQKGKRLLLPFGNESEGVMYDMNQSLVPPGLPIPVTSQGYSLAPSPPVYMPPFHKAEMFPPPLQPGISMNNSSH
What is the function of this protein?
Required for the maintenance of pluripotency and self-renewal of embryonic stem cells.  Transcriptional activator that binds the DNA consensus sequence 5'-ATGCAAAT-3'.
What are the official names of this protein?
POU domain, class 5, transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPD2A_HUMAN
Sequence: MLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLAQGSPAVARIAPQRAQISSPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVPPPAPPSKPKEAEEGPTGASESQDSPRKLKYEEPEYDIPAFGFDSEPELSEEPVEDRASGERRPAQPHRPSPASSLQRARFKVGESSEDVALEEETIYENEGFRPYAEDTLSARGSSGDSDSPGSSSLSLTRKNSPKSGSPKSSSLLKLKAEKNAQAEMGKNHSSASFSSSITINTTCCSSSSSSSSSLSKTSGDLKPRSASDAGIRGTPKVRAKKDADANAGLTSCPRAKPSVRPKPFLNRAESQSQEKMDISTLRRQLRPTGQLRGGLKGSKSEDSELPPQTASEAPSEGSRRSSSDLITLPATTPPCPTKKEWEGPATSYMTCSAYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYLVLDENEQPDPSGKELDTVPAKGRQNEGKSDSLEKIERRVQALNTVNQSKKATPPIPSKPPGGFGKTSGTPAVKMRNGVRQVAVRPQSVFVSPPPKDNNLSCALRRNESLTATDGLRGVRRNSSFSTARSAAAEAKGRLAERAASQGSDSPLLPAQRNSIPVSPVRPKPIEKSQFIHNNLKDVYVSIADYEGDEETAGFQEGVSMEVLERNPNGWWYCQILDGVKPFKGWVPSNYLEKKN
What is the function of this protein?
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells.  Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides.  Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization.  In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
What are the official names of this protein?
SH3 and PX domain-containing protein 2A, Adapter protein TKS5, Five SH3 domain-containing protein, SH3 multiple domains protein 1, Tyrosine kinase substrate with five SH3 domains.
What is the protein family that this protein belongs to?
Belongs to the SH3PXD2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, podosome. Note=Cytoplasmic in normal cells and localizes to podosomes in SRC- transformed cells.
Protein: Y5274_BACC4
Sequence: MTENNDIKMVIITGMSGAGKTVALQSFEDLGYFCVDNLPPMLLPKFIELMADSKGKMNKVALGIDLRGREFFEHLWGALDDLSERTWIIPHILFLDAKDSTLVTRYKETRRSHPLAPTGLPLKGIEAERNLLTDMKARANIVLDTSDLKPKELREKIVHLFSTETEQAFRVNVMSFGFKYGIPIDADLVFDVRFLPNPYYIPHMKPLTGLDEEVSSYVLKFNETHKFLEKLTDLITFMLPHYKREGKSQLVIAIGCTGGQHRSVTLTEYLGKHLKPEYSVHVSHRDVEKRKGH
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BCB4264_A5274.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RIHB_ECO55
Sequence: MEKRKIILDCDPGHDDAIAMMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.  Has a clear preference for cytidine over uridine.  Strictly specific for ribonucleosides.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihB, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihB subfamily.
Protein: TXF3A_SCOAL
Sequence: MKMVYLGLFLIITSCVISSGNLIYECRWVDTIRVKDPTNELCQKKCEETFTGRITVKHGYASSERRCACYGEKVLETPYPSDGVKDCNRI
What are the official names of this protein?
U-scoloptoxin(15)-Sa3a, U-SLPTX(15)-Sa3a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-15 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4200_BURP1
Sequence: MMLHIPGVLTKEQVAQCRDILDAADWTDGNATSGAQSALAKRNRQLPEGSPAARAAGDAIQDALACNALFFSAALPLKVFPPLFNRYAGGDAFGTHVDNAIRLLRGTDFRVRSDLSATLFLEEPEHYDGGELCVEDTYGVHRAKLPAGDMVLYPASSLHHVTPVTRGARVASFFWIQSMVRDDADRTLLYQLDTQIQRLTAEKGGRDASVIALTGIYHNLLRRWADA
What are the official names of this protein?
PKHD-type hydroxylase BURPS1710b_A0200.
Protein: IORF_CVMS
Sequence: MESSRRPLGLTKPSALEIMEIEAEGISQSRLQLLNPIPGVWFPITLGFRALPNSRREKSFSLYKDRECLLPMESQLQSKRDIGIDTTDVLLKHLMASRSSYCPDGIFTISEQGPMLAQSMATISKELSGSQANRPTLRPLPILLKGTQVAMRLFLLGLRPVRFCLRVFMLKAQEGLHLLADLVRGHNPVGQIIALEAAPTSASLPLL
What is the function of this protein?
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host.
What are the official names of this protein?
Protein I, Accessory protein N2, N internal ORF protein, IORF, Protein in nucleocapsid ORF.
What is the protein family that this protein belongs to?
Belongs to the coronavirus I protein family.
What are the subcellular locations of this protein?
Virion.
Protein: YHI4_SCHPO
Sequence: MSMLIFNIRVARHKALLSRIVSTNMFNPMFRSLRPIQKSFSEISILRVFNKPPIKKFHNSNILKDITSKRNATPAKIAWQAMTTREPFLVYQAKADKKISLIYLLTVGMLINVCVITSFASVDIYRAKDEIFANWVDMDYYEKLSYIGSAFITPALYFTLTLILFLPRRNIYSISTLPSQRFEIVTGFLSPFNKLYFSKSLIVPRKDVSIVTYSLQKNPITLKIRDRPFYYLLNANGKYAGNSKDVLFCVIGNRY
What are the official names of this protein?
Uncharacterized membrane protein P22H7.04.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RLME_BARBK
Sequence: MKKTTRRTAGGRGGAGSHELYQRVKKKAGTIKASSRRWLERHLNDPYVHQSKADGYRSRAAYKLIEINERYKILKKGQKIIDLGAAPGGWCQVAARLVESKDYNPSVVGIDYLHMEPLPGVAILEMDFFHEDAPQELISTLGSKPDVVLSDMAAPTTGHRQTDHLRTIALCEAAVHFSISVLKPGGHFLTKTFQGGAEGNLLATLKQNFKKVHHVKPPASRAESVELYLLALQFKGKTD
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_HAEI8
Sequence: MATKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGNNVGMGRDHTLFATADGKVKFEVKGEKSRKYVSIVTE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PTH_BUCA5
Sequence: MIVGLSNPKKEYHSTRHNVGSWYLYSLAESYLRNFKNEKKFFGFTTSLNIESNYIRLLIPNIFMNINGQSVFKMASFYNINLSEILIVHDDLELQPGISKLKYSYGHNGHNGLRDIVNTFNKNINFYRFRIGIGRPINRDQIASFVLSNPTKKEKILIQKSILHAIEKNVLSNILKF
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_CAUVC
Sequence: MNLILFGPPAAGKGTQAKRLVTERGMVQLSTGDMLRAAIASGSELGQRVKGVLDRGELVTDEIVIALIEDRLPEAEAAGGAIFDGFPRTVAQAEALDKMLAARGQKIDVVLRLKVDEPALIERIKKRFEEQGRPDDNPEVFVTRLAAYNAQTAPLLPYYEGQGKLTELDGMGTVEAVAASIDSALEPVAAG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_PSEF5
Sequence: MEALHKKIREEGIVLSDQVLKVDAFLNHQIDPQLMKLIGDEFATLFKDSGITKIVTIEASGIAPAIMTGLNLGVPVIFARKHQSLTLTENLLSATVYSFTKQVESTVAISPRHLTSSDRVLIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQGGRAELDSQGYRVESLARVKSLAGGVVTFIE
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDS1_YEAST
Sequence: MSHHVPNLYGTPIRDPHERKRNSASMGEVNQSVSSRNCERGSEKGTKQRKKASHACDQCRRKRIKCRFDKHTGVCQGCLEVGEKCQFIRVPLKRGPAKKRGSVVSIEKFSSDNDPLQYRPRTHSYPMNSGNNYLPSLARNSSFPSISSLFVPSITAQSQQFVKVPYDDIKRRSSLAILGSDSSISTEFGGNYRLDENLNVRQEGKDIVAKGMITPVEEMGACSSNVRRQGSQSLPIQEQRASPYINPFISGRSRLSSLSYTSEATTSEGNTQGKNQCMLTPNSVRSIEKERLNSLTAGFPNKKLGTDGRSDKWDKNSTWKPVYRSSNPSHPSTEKNVSLNQEASAKPLMLGTYRQFDATSFYKVLGIYYNFFHINFPVIPINKSKFTDMLDPEKPNVIDEIRQINNEIIQCFKTALEVLVFCKIKQRRSSKSTKSWSRDSLCDFQKGLYYIQNFNKCIADCFQSLITIKPVLKQNSSVIPSRIKFIYFSTIIVLNFILILAGEESSLLLGPSVGVFNEFQAHKLFLPFQNTSPMLLLNSNEESGDEILDYAVLFKRLYILLNILDTLQSFRLGQPKLINLNFGSAIETYFSDKTGHNQVVEKAPVALDNILRNLKLGEFITYFVLNRKSLQVNVPHHLLFTNQTDYGEFAVEKGEHDNIAGKFETLLKKKEILIRKLLNIEQKNDHILENCCNSDAEMKNIGELVCSMITLVSGILDSITNMNAENSVDLDSKPLPNAYFAQDSEEELMSPTQSITSNLASEENTRCTTKDLMGTVSIFMLPMVEECYNIISLIGPIPTTLISLYIRNGNMAKGINDRIMTLSTALNELVQITALFNTLEPFRKNAHDRAKRYYVSATSSTGCYESVMKSMYSGKCAASNASNVAPSEEENKKILKKFADIGWKLMDDSELGCCCCFFN
What are the official names of this protein?
Transcriptional regulatory protein EDS1, Expression dependent on SLT2 protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDS1/RGT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BRE1A_ORYSI
Sequence: MGSTGEPDRKRRLSSSVAPGGGAPVSPAKRLAVAPTSEDKKLDFTVLKYKNQKLSEQLEAHKFEYRALENKFAGLKEKQRTHNETLSLVNSSWEQLVADLKSRSFCKSGSPNSSPGSGHNNVQKDGTCAPIERDTLRSLVESGATESSGCLPGCHLGSDAPPLHLSTANALGDIFFPSSDLLQANEECALAALTKLPENDRSKQLQSTSSNLLSSLNNVVQALSNLQLKHKQLAEDYQNQRDSSARKRAEHRRLKEELASAASELEETNYKLAALKAQRDNTQGARIPYPTLGNKSMPEDKVRDKQREMQDLEATHKELSELISKRLVEIKRLHEERIEILNKIATFQNILMDFKSIRSSKAFQLVNDRLQKSQAELDHYQTLLEKLQVDKDKFVWQERQFNLKVDLAEIPERVSTYCESSIADLKKDIQKLRDEKNMLILKLEEASREPGRNQVITKFKALVSSIPREMGAMQSEMTKHKEASLELNSLRAEVHSLSRILSRKERDNEEASCRSARAGSDITQLQSVISDLKQTNKELKLFADMYKRESTDSREIMESRDREFLEWAHVHALKSSLDESKLEQRVKAANEAEAITQQRLATAEAEIAESGQKLGTSRKDLVSLSHMLKSKQEECEAYRVEVECIGQAYEDIQAQNQQLLQQIIERDDDNTKIFMEGVKAKQTQDALHLETYSLRRNLQQESSLMDLYNQKIVSLEDQLKMWSDRVGKLQEDGWQQSVSLSNYQRKLVDVHRDAQKLMQSLDGIQANVGSSRLEVADLLIELEKERFSKKRIEDDLEVMSRKASSLRAKARESAVLEKLRHEVKEYRGILKCGICHDRQKEVVITKCYHLFCNQCIQKSLGNRQRRCPSCSLSFGANDVKPIYI
What is the function of this protein?
E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1.  H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me.  It thereby plays a central role in histone code and gene regulation.  Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6.
What are the official names of this protein?
E3 ubiquitin-protein ligase BRE1-like 1, RING-type E3 ubiquitin transferase BRE1-like 1.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASNA_DROSI
Sequence: MADNLEPLEPSLQNLVEQDSLKWIFVGGKGGVGKTTCSSSLAVQLSKVRESVLIISTDPAHNISDAFDQKFTKVPTKVNGFDNLFAMEIDPNAGLNELPEEYFDGENEALRVSKGVMQEMINALPGIDEAMSYAEVMKLVKGMNFSVVVFDTAPTGHTLRLIAFPQVVEKGLGKLLRLKMKVAPLLSQFVSMLGMADVNADTLSQKLDDMLRVITQVNEQFKNPDQTTFVCVCIAEFFSLYETERLVQELTKCGIDVHNIIVNQLLFLQKSHDSCSMCASRFKIQEKYLDQIADLYEDFHVTKLPLLEKEVRGPESIRSFSENLMKPYDPKAEPKE
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: GATB_LEPIN
Sequence: MAEFETIIGLEVHAQLNTESKIFSTSATKFGSPPNSQTNPVCLGLPGALPVLNEFALEKAIMAGLAFGCDITLFTKFDRKNYFYPDLPKGYQISQFDKPICTGGGVTFTIKGEDSARYVRLTRIHLEEDAGKLIHSADPNIPQSYVDLNRAGTPLIEIVSEPDMRSSDEAYYYLNSLKSVLKYIRVSDCNMEEGSLRCDANVSIRPKGSDKFGTRVEIKNLNSFKAVKAAIDYEVEWQKEMALEGKTFQQQTKLWDSVANKTVTMRTKEMSHDYRYFPDPDLPVIVLQKETVESVRSKLPELPNERKNRFVEKLGLPKYDAEVLTAEREVADYFEDALKVSGDAKKTSNWVKDEILGIVNKENITISEFSVSARRIGELVKLIADGKISGKIAKTVFEELLTSDKDAETIVTEKNLIVVRDDKEIERIVDEAIANNQDAVTKYKSGKDRALGAIVGYVMKVSKGKADPELVNQMLLEKLGPLPPKS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: TRMB_BURCH
Sequence: MMHDDPNEAGLPPHNDAIPDETAEGADEVNPLHHRRIRSFVTRAGRVSTGQRRALDEFGPRFVVPYAPEMPDWDAIFGRSAPRILEIGFGMGASTAEIAAHRPSDDFLGVEVHEPGVGALLKLIGEQGLSNIRIIQHDAVEVLEHMIAPASLDGVHIFFPDPWHKARHHKRRLIQPPLVAHLASRLKPGAYLHCATDWQNYAEQMLEVLGAEPTLENTAADYAPRPDYRPVTKFERRGLRLGHGVWDLVFRKRAD
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: HIS3_GEOSM
Sequence: MIKIDFEKMGGLIPAVIQDNESGEVLMVAFMDEKTLNLTLESGKTWFFSRTRNKYWMKGEESGNTQDVVEVLTDCDADTVVIKVKQNGPAACHTGNRSCFYVKYENGSWVEHSNPLFDPNTVYKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BACC4
Sequence: MRKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQIPPHKQGRNITSVESRLHMLELATEAEEHFSICLEELSRKGPSYTYDTMLQLTKKYPDVQFHFIIGGDMVEYLPKWYNIEALLNLVTFVGVARPGYTLHTPYKITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: GATC_METSB
Sequence: MSVDQATVRRIAHLARIKVSDEDVPHLQDELNAILRFVEELAAVDVEGVEAMTSVMPMPMKKRQDIVTEGEIPDVILANAPEREDHFFKVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: HYFLB_HYBFL
Sequence: GSPIQCAETCFIGKCYTEELGCTCTAFLCMKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide Hyfl-B.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: BPHC_SPHPI
Sequence: MVAVTELGYLGLTVTNLDAWRSYAAEVAGMEIVDEGEGDRLYLRMDQWHHRIVLHASDSDDLAYLGWRVADPVEFDAMVAKLTAAGISLTVASEAEARERRVLGLAKLADPGGNPTEIFYGPQVDTHKPFHPGRPMYGKFVTGSEGIGHCILRQDDVPAAAAFYGLLGLRGSVEYHLQLPNGMVAQPYFMHCNERQHSVAFGLGPMEKRINHLMFEYTDLDDLGLAHDIVRARKIDVALQLGKHANDQALTFYCANPSGWLWEFGWGARKAPSQQEYYTRDIFGHGNEAAGYGMDIPLG
What are the official names of this protein?
Biphenyl-2,3-diol 1,2-dioxygenase, 2,3-dihydroxybiphenyl dioxygenase, DHBD, 23OHBP oxygenase.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: YBX5_SCHPO
Sequence: MSFVDGVNSWFSAASYWDGLGPTNVVQPEDDLAFVSQFEEVESAYDNLVKNGMIAPRRKNSFASSVNNPFSTSALSEALNGSVSMSHVPSSGLLKSTLSSTPTAGSNLLGTSPAEPASGLVGSSGFGSSMLGSSLPGNATSNFGSQASTSLLHPRRSTTSLLSSSAHHSRSSYYDLATPTRSSFSYNTVGAASLPSGGLSNLSSSLRSSSKSAGFSLFESASNSFTPSSFIESANMESLSIPSRRRPSSIAPIGTRPSRKEIAFSNSSTPTDQTLRPPNPPAANGNATPVTAVNNVSAVADSPQSTGSSVSSSLPTLSLDFKQEYSGNNHDMSGLSSSLSKSHNSTSALSSQIWSSPCASTLGGVNVW
What are the official names of this protein?
Uncharacterized protein C17D1.05.
Protein: ARLY_ECO8A
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLDELQKFSPVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1GLT_MOUSE
Sequence: MASKSWLNFLVFLCGSAIGFFLCSQLLSILLREEAAIQPNMLHNDPHARHSDDNGHSHLKGQMNFNADSSQHKDENIDVAENLYQKVKILCWVMTSPQNLEKKAKHVKATWAQRCNKVLFMSSEENQDFPTVGLKTKEGREQLYWKTIKAFQYVHDHYLEDADWFMKADDDTYVIVDNLRWLLSKYNPEQPIYFGRRFKPYVKQGYMSGGAGYVLSKEALRRFVNAFKTEKCTHSSSIEDLALGRCMEIINVEAGDSRDTIGKETFHPFVPEHHLIKGYLPKTFWYWNYNYYPPIEGPGCCSDIAVSFHYVDGTTMYELEYLVYHLRPYGYLYRYQPALPENILKEINQVNRKEDTKIKLGNP
What is the function of this protein?
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.  Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
What are the official names of this protein?
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, Core 1 O-glycan T-synthase, T-syn, Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1, Core 1 beta1,3-galactosyltransferase 1, C1GalT1, Core 1 beta3-Gal-T1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.