PharMolix/UniProtQA huggingface dataset:
Protein: CD47_BOVIN
Sequence: MWPLVVVLLLGSVRCGSAQLIFNAIKSVEYTLCNQTVVIPCFVNNVETKNITELYVRWKFKGENIFIFDGSQRMSKPSSNFSSAEIAPSELLRGIASLKMAKSDAVLGNYTCEVTELSREGETIIELKYRVVSWFSPNENILIVIFPVLAILLFWGQFGIVTLKYKSNYTKEKAIFLLVAGLLLTVLVIVGAFLFIPGGYSTKNASGLGLIVLPTIILILLHYCVFMIAMGMSSFTISILILQLLGYVLSVVGFSLCVSECIPVHGPLLISGLGIIALAELLGLVYMKCVASNHRTIQPPRNN
What is the function of this protein?
Adhesive protein that mediates cell-to-cell interactions.  Acts as receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins.  Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation.  Plays a role in modulating pulmonary endothelin EDN1 signaling (By similarity).  Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure (By similarity).  Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity).  Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.  Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation (By similarity).  Positively modulates FAS-dependent apoptosis in T-cells, perhaps by enhancing FAS clustering (By similarity).  Plays a role in suppressing angiogenesis and may be involved in metabolic dysregulation during normal aging (By similarity).  In response to THBS1, negatively modulates wound healing.  Inhibits stem cell self-renewal, in response to THBS1, probably by regulation of the stem cell transcription factors POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 (By similarity).  May play a role in membrane transport and/or integrin dependent signal transduction (By similarity).  May prevent premature elimination of red blood cells (By similarity).
What are the official names of this protein?
Leukocyte surface antigen CD47, Integrin-associated protein, IAP.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLH26_FORAG
Sequence: MFCYSSLHAQIISGTVSAEGQVLPGAAVIIKGSTKGTSTDFDGYYTIEAQASDVLVFSYVGYANKEVTVGTNTQIDVALEADNTLDEVVVIGYGTQRKSDLTGSVSSVSAEDVNVNPVSRVDQALQGRAAGVQVTQTSGAPGAASVIRVRGGNSITGSNEPLWVIDGIVVGTNFNLNNINSNDIKSIEILKDASSIAIYGSRGANGVVLVTTKTGTGAGSSKPEVSANIYTSMQMVPELPKMLSQAEQIAYTNESAAFRGAAIPFPNDPSTYPNNDWFDLLLGPAPIYNADVSITGASENVSYYTSLNYFNQEGIVKTSGIEKYIFRSNLDIRLSDKLKTGFRVNYSYIDQQNGLVGYGNAIATLPTQPIYNEDGSYNGFDEVVGSPWSNPIANMALNTNETFRNNFLGSFYIDYSPSEKWIIRSTFSPDFDNSKQNRFTSSQSPNLLYLGEGGNASVRTVNTKGWNNENTIQYQSEIGENHRITALGGASFQKVSTEIVESEAFGITNDATGFNNLSNSDPTRNILTSDYSGFQIASFFGRLNYAYKDKYLLTLVGRTDGSSVFSDDNKYEFYPSIAAAWKISEEGFMQNQETFGELKLRASYGKSGNQAIDPYRTKGLLVEANTTLNGIQQTGLTLGRPSNPNLTWETTNSLDIALEASMFNGRVFAELNYYYKKTNDLLLDVTIPKQTGFNSQLQNVGSLENKGWEFSLNTTNVRTDNFNWKSTLMLSSNKNKILDLGGVDFIDLVVDELLGSGNTRLIVGESVPVFTGVKFLGTWKSQEEIDASGLRDPQVVGGAKYHDENGDGIISTDDAVVLGSPLPDLIFGFENTLSYKNLDFSFYFQGTQGNEVYNLRMRNHYFNRGEFTKFAEVADRWTPENPTSDIPRAGGDSVTGTPPNSAYVEDGSHIRLKTVRLAYNMPVDKMGMDGVKNATVYLTGTNLLLWSDFRLIDPEGSNFGRNGIGNIAQGYNDGSYPNPRTITLGLNVTF
What is the function of this protein?
TonB-dependent receptor probably involved in ulvan degradation (Probable).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).  The TonB-dependent receptor may mediate transport of ulvan oligosaccharides from the surface of the outer membrane to the periplasm for subsequent degradation (By similarity).
What are the official names of this protein?
TonB-dependent receptor P26, P26_TBDR, Polysaccharide utilization locus H protein P26, PUL H protein P26.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: Y1405_YERPS
Sequence: MSAYSRPVLLLLCGLLLFTISIAVLNTLVPLWLSHQQLPTWQVGMVSSSYFTGNLVGTLIAGRFIQQLGFNRSYHCSCILFALATCGLMLTVDFWSWLGWRFLAGIACALIWVIVESALLRSGTLTNRGQLLAAYMMVYYLGTVIGQLLLGIVSTQLLSVIPWVGALVITAMLPLLFAQFSHQSRHESPPIAVWPMLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGWMALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVVILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKASADELVAMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFIMIAGVAFVYLMMLLRKPDHQQTPYAAV
What are the official names of this protein?
Uncharacterized MFS-type transporter YPTB1405.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRG_ACIC5
Sequence: MSAKYIFVTGGVVSSLGKGLAAASIGCLLEARGLRVNLMKFDPYLNVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFTHARLTRDNNLTTGRIYEQIITKERRGDYLGKTVQVIPHVTNEIKNAMRKVAADGDVTIVEIGGTVGDIESLPFLEAIRQMRQELGRENTVFVHVTLVPWISAAQELKTKPTQHSVKEMLSIGIQPDILLCRTDRYLPHDIKSKIALFCNLEEKAVITAKDVDSIYEVPLVFAQEGVDKLALRYLHLDTREPDLSRWSALVERCYHPTGEVSIGIVGKYVEYEDSYKSLKEALVHGALAEGLKLRVTWIEAEGLEAPNYEQQLSGFDGILVPGGFGKRGVEGMLNAIRYARENKVPYFGICLGMQTACIEFARNVCGLQGANSSEFDPATPHRIIYKLRELTGVEEMGGTMRLGAWACVLQNGSLAADAYGKTEISERHRHRYEFNREYEAVLTGAGLRISGTTPDSTYVEIVEIPDHPYFLGCQFHPEFKSKPLEPHPLFHAFVKAAYQNHKPHTEATQPAAESAPIGK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PURL_STAAN
Sequence: MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMB5_MAIZE
Sequence: MASGQESRKELDRKAREGETVVPGGTGGKSVEAQEHLAEGRSRGGQTRREQLGQQGYSEMGKKGGLSTTDESGGERAAREGVTIDESKFTK
What is the function of this protein?
LEA proteins are late embryonic proteins abundant in higher plant seed embryos.  They may play an essential role in seed survival and in controlling water exchanges during seed desiccation and imbibition.
What are the official names of this protein?
Late embryogenesis abundant protein EMB564.
What is the protein family that this protein belongs to?
Belongs to the small hydrophilic plant seed protein family.
Protein: TYSY_GLAP5
Sequence: MKQYLDLCQRIVEQGKWVENERTGKRCLTVINADLTYDVAKGEFPLVTTRKSFWKAAIAELLGYIRGYDNAADFRQLGTKSWDANANENAAWLTNPHRKGEDDMGLVYGAVGRNFPKVGGGSVDLLRQIVDDLKRGVDNRGEIYTFYHPGAFHMGCLRPCLHSHHFSLLDGTLYLNSTQRSADVPLGLNWNMIQCYTFLALMAQITGHQAGQAFHKIVNAHIYEDQLELMRDVQLKRTPFKAPTLKINPDIKSLEDLETWVTLADFEVEGYEYHPSIQYPFSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPCS1_BOVIN
Sequence: MLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYLAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQDSSTEDKKPGERKVKRHAKNN
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Dispensable for SPC enzymatic activity (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 1, Microsomal signal peptidase 12 kDa subunit, SPase 12 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NINB_BPP22
Sequence: MKKLTFEIRSPAHQQNAIHAVQQILPDPTKPIVVTIQERNRSLDQNRKLWACLGDVSRQVNWHGRWLDAESWKCVFTAALKQQDVVPNLAGHGFVVIGQSTSRMRVSEFAELLELIQAFGTERGVKWSDEARLALECKARFGDAA
What are the official names of this protein?
Protein ninB.
What is the protein family that this protein belongs to?
Belongs to the ninB family.
Protein: AAEA_YERPG
Sequence: MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQPRYQQALAEAEADVAYYQTLAAEKQRESSRRHRLGIQALSQEEIDQASNVLQTVQHQLAKAIAVRDLARLDLERTTVRAPAEGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSADSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQASPMTKLMHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NIKR_METJA
Sequence: MTEMDRISISLPSKLLREFDEIIAERGYASRSEAIRDAIRDYIIKHKWIHSLEGERAGSISVIYNHHASDVMEKITEIQHNYTDIIVATLHLHLDHDHCLETILVRGDAKRIRELTDRLTALKGVKQVKLSVMVPGGQIPE
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RL31B_BURCH
Sequence: MKPGIHPDYREVVFQDMSNGFKFITRSTIQTRETIEHEGKTYPLAKIEVSSESHSFYTGQQKIMDTAGRVEKFKNKFGARANGKAAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: TPIS_AERPE
Sequence: MKPVLAVNMKTYSSAFGEGARRLARDAARVAREVDVRVILVAPLINASSLAGVYGDVYIQHADPVDLGAHTGYTPVEAAAAEGLRGVMVNHSEHKVTYRHLQAVVSKARSLGLEVLACADTPEEAAAAALLRPSMVALEPPELIGTGIPVSQAKPEVITRGVEAVARVAPGVAVLAGAGITAGEDARRAVELGAQGVLVASAVMKAKDPHGKMLELAEAMAKP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCK1_DELRA
Sequence: NSVVLGKKQRFHSWG
What is the function of this protein?
Acts through intracellular calcium in Malpighian tubule stellate cells to raise chloride conductance.
What are the official names of this protein?
Leucokinin-like peptide.
What are the subcellular locations of this protein?
Secreted.
Protein: FABZ_BACAA
Sequence: MLDIQQIKEIIPHRYPFLLVDKVLEVEEGKRAIGIKNVTANEEFFNGHFPDYPVMPGVLIVEALAQVGAVAMLKKEENRGRLAFFAGIDNCRFKRQVRPGDQLRLEVEMTRVRGAIGKGKAIATVDGEIACETEITFALGDKKE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V211_FOWPN
Sequence: MKEPLIEVKREYNLIKTLTGKKFVVSTSIVVVLLIINMIFYGIRIHELAVIRRNSETHISSFNYKGQAQAQNKRVKNTRLFEKCKSKFNNFCIYGECMNIINLDKKFCICNKGYTGNRCDIVSIR
What are the official names of this protein?
Probable growth factor FPV211.
What are the subcellular locations of this protein?
Secreted.
Protein: RL16_VIBVY
Sequence: MLQPKRTKFRKVHTGRNRGLAKGTEVSFGSFGLKAVGRGRLTARQIEAARRAMTRHIKRQGKIWIRVFPDKPITEKPLEVRQGKGKGNVEYWVAQIQPGKVMYEVDGVPEELAREAFRLAARKLPFKTTFVTKQVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DDL_POLSJ
Sequence: MSSNADTSQAVSAGTSVGATFGKVAVLMGGMSAEREISLMSGRGVLQALRSRGVDAHAFDPAERDISELKKDEFARCFIALHGRFGEDGTVQGALELLGIPYTGSGVMASSMAIDKVMTKRVMLAEGLPTPTYVLLRRGSYGSADVSAVPDKLGLPLIVKPAREGSSIGLTKVTERAGMADAVAQAEKLDADILCEQFISGDEVTCPVLGTGSEARALPVIRIVAPDGNYDYQNKYFTDTTQYLVPCGLPEGEEAVIQQLVLQAYRTLNCRGWARADVMIDKVTRKPYLLEINTSPGMTGHSLVPMSARAAGISYEDLCIEVLKTTALDHQSQGGGAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRL_PAROL
Sequence: MTHRRTKLFMMAAVVSYVMTSCGAVPINDLLDRASQRSDQLHSLSTTLSQELDSHFPPIGRVIMPRPSMCHTSALQTPNDKTQALQVSESELLSLARSLLQAWADPLSALSSSAFSLPHPAQSSIFNKVREMQEHSKNLGDGLDILSGKMGEAAQALSSLPFRGNDVGQDRISKLINFHFLLSCFRRDSHKIDSFLKVLRCRAANTQPEMC
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2158_LISMO
Sequence: MSEDKGMKDKAKGLKDKVVGDAKDKFGKATDDKGKQVEGKAQKAKGEVEDKTGDAKKKLSE
What are the official names of this protein?
UPF0337 protein lmo2158.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: ATPG_MAIZE
Sequence: MSCSHLSTAWSSSALASSASTTRRRSPPRSGLLVRCSLRELRTRIDSVRNTQKITEAMKLVAAAKVRRAQEAVVSSRPFSEALVEVLYNMNQEIQTEDIDLPLTRTRPVKKVALVVLTGERGLCGSFNNNVLKKAETRIDELKQLGLQYTVVSVGKKGNAYFQRRPYIPLERDLEVSSVPTVKDSQAICDLVYSLFVSEEVDKVELLYSKFVSLVRSDPIIQTLLPMSPKGEICDVNGVCVDATEDELFRLTTKEGKLTVEREKVKIETQPFSPVVQFEQDPVQILDALLPLYLNSQILRALQESLASELAARMSAMSSATDNAIELRKNLSIAYNRQRQAKITGEILEIVAGADALAG
What is the function of this protein?
Inceptin is a proteolytic fragment produced by insect larvae that previously ingested the protein.  This peptide mediate plant perception of herbivory through the induction of volatile, phenylpropanoid and protease inhibitor defenses such as ethylene, jasmonic acid and salicylic acid for example.
What are the official names of this protein?
ATP synthase subunit gamma, chloroplastic, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RPOA_MARMM
Sequence: MIEKNWQELIRPMKPEIEPGHDPARQAKIVAEPLERGFGMTLGNALRRVLLSSLQGAAVTNVHIDGVVHEFSSIDGVREDVTDIVLNIKQIALRMHGEGPKRVVLKKSGPGIVTAGDIEETADVEIVNKDLALCTLDEGAEIRMEFTINTGKGYVPSERNRPEDAPIGLIGVDALYSPVKRVSYKVENTREGQVLDYDKLTLEVETDGTVTPEDSVAFAARILQDQFQIFINFEEAVEARPAEDDKPELDFNPALLRKVDELELSVRSANCLKNDNIVYIGDLIQKSEAEMLRTPNFGRKSLNEIKEVLAQMGLHLGMEAPNWPPENIEDLAKRFEDHV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: EFP_PROMP
Sequence: MISSNDFRTGTTIEIDGQVWRVVEFLHVKPGKGSAFVRTKLKSVRNGNVVEKTFRAGESVQQAVLEKSNLQHTYVESGDYVFMDMISFEETRLSSDQIGRGSKYLKEGMEVNVIFYKDKVLEVELPISITLKVTETDPGVKGDTASGGTKPAILETGAQVMVPLFISVGEMIKVDTRNDSYLGRDN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHCAF_PONAB
Sequence: MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRIKSNQISKLQKEFRRHNSDAHSTTSSASPAQSPCYSNQSDDGSDTEMASGSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLFKPCCSNKKAAAEKPEEQGPEPLPISTQEW
What is the function of this protein?
Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway.  Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells.  Promotes the stability of SIN3A and its presence on chromatin and is crucial for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming.
What are the official names of this protein?
SIN3-HDAC complex-associated factor, Protein FAM60A, Tera protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SINHCAF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROB_SALTY
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQMLLTRADMEDRERFLNARDTLRALLDNHIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQQGLFTADPRSNPQAELIKDVYGVDDALRSIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIASGSKPGVIGDVMEGISVGTRFHAQASPLENRKRWIFGAPPAGEITVDEGATAAMLERGSSLLPKGIKSVTGNFSRGEVIRICNLQGRDIAHGVSRYNSDALRRIAGHHSQQIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_BACCQ
Sequence: MMTYEYILVRYGEMTTKGKNRSKFVSTLKDNVKFKLKKFPNIKIDATHDRMYIQLNGEDHEAVSERLKDVFGIHKFNLAMKVPSELEDIKKGALAAFLQVKGDVKTFKITVHRSYKHFPMRTMELLPEIGGHILENTEDITVDVHNPDVNVRVEIRSGYSYIMCDERMGAGGLPVGVGGKVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPPFTSERAKQKVIDLAQELTKYCKRVTLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMRITERIAEERNALAITTGESLGQVASQTLDSMHTINEVTNYPIIRPLITMDKLEIIKIAEEIGTYDISIRPYEDCCTVFTPASPATKPKREKANRFEAKYDFTPLIDEAVANKETMVLQTVEVVAEEEKFEELF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COL11_DANRE
Sequence: MVGEKLVAYMLVSVLGLALLRSVFGQHMPEEPCSVQILVPGLKGEAGEKGEKGAPGRPGRVGPTGEQGPPGDKGQKGSPGRYGKMGPTGPKGLKGDMGDPGPKGPNGEPGVPCECAPLRKMIGEMDIQVVQLTNELKFIKNAVAGIKETDSKVYLLVKEEKRYREAEVFCQGRGGHLAMPKDAAANRAIAGYVTDAGLSRVYIGINDLEREGHFVYVERSPMTTFSRWREGEPNNAYDDEDCVEMVSSGEWIDVACQLTMYFVCEFDKDTV
What is the function of this protein?
Lectin that plays a role in innate immunity, apoptosis and embryogenesis.  Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope.  Primarily recognizes the terminal disaccharide of the glycan.  Also recognizes a subset of fucosylated glycans and lipopolysaccharides.  Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1.  Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (By similarity).  Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis (PubMed:21258343).
What are the official names of this protein?
Collectin-11.
What is the protein family that this protein belongs to?
Belongs to the COLEC10/COLEC11 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DIRC1_HUMAN
Sequence: MPEAHMQPAKLQTSLPTTDHGSKKPVSCYLPPLSNAHPMCIEVQNAQNCSSAAATLEPSIISDTCFYKPITKDQLSSRSELNTVRLKCLNSLRGWKILNQLSLT
What are the official names of this protein?
Disrupted in renal carcinoma protein 1, Disrupted in renal cancer protein.
Protein: ACPS_YERE8
Sequence: MAIIGLGTDIVEISRIEAVVERSGEKLARRILSPAEWQHYQQHQQPIRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVVNDALGKPTLRLHQRAAELAAELGVKSLHVTLADERRYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.