PharMolix/UniProtQA huggingface dataset:
Protein: SYH_MICLC
Sequence: MSRKASLSGFHEWLPAERLVEQHVLDTLRRTFELHGFAGIETRAVETLGQLLRKGEVDKEVYAVSRLAEDEEVAAGRREPKDPADPKRLALHFDLTVPFARYVVENAGHLAFPFRRYQMQKVWRGERPQEGRAREFTQADIDVVGDGALSPRYDADVALVMAEALGALPIGDFLIRVNNRKLAEGFYRGIGLEDTAGVLRSIDKLEKVGPEEVARLLQEEVGASPEQAAQALALADIRTSDTSFVERVRALGVTHELLEEGLTELADVVATLHRRAPGRAVADLSIARGLDYYTGTVYETVLVGHEQLGSICSGGRYDALASKGNRVFPGVGLSIGVTRLVMRMLSQQMAVASRSVPTAVYVALTADEDWSEAQDVAALLRERGIPAEVAVSAEKFGRQIKYADRRGIPFVWFMGRDDAGARVHEVKDIRSGEQHAADPADWTPPAEDLLPQVARAQD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNB_PYRTR
Sequence: MASNDIDAEALVHSDDPSHPANHICTLCAKFYNLGWVTGTGGGTSIRHEDKIYIAPSGVQKELMKPTDMFVMDFNSKEYLRKPQVLKPSACTPLFLAAFERGAGCCIHTHSQWAVLVTLIVERDFGKDACFEIEEIEQIKGIPKGRGKQGNLGYYDRLRIPIIENTAHEEDLRESLEEAMEKYPDSYAILVKRHGIYVWGDNVHKAKTQCESIDYILQLAVEMKKLGLPWTK
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALT1_BOVIN
Sequence: MRKFAYCKVVLATSLIWVLLDMFLLLYFSECNKCDEKKERGLPAGDVLEPVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMLEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRHKLQCRPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATDEDSQVPSIRDCSGSRSQQWLLRNVTLPEIF
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:3082881, PubMed:7685345).  Has a broad spectrum of substrates such as apomucin-, MUC5AC-, MUC1- and MUC2-derived peptides (By similarity).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 1, Polypeptide GalNAc transferase 1, GalNAc-T1, pp-GaNTase 1, Protein-UDP acetylgalactosaminyltransferase 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
[Polypeptide N-acetylgalactosaminyltransferase 1]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Polypeptide N-acetylgalactosaminyltransferase 1 soluble form]: Secreted.
Protein: CY1_DICDI
Sequence: MFSQKLLANGKLLSKLAIVSGVVGTATAITTSTTLLSDDFVQPTSYPWEHRFPWQSYDHAAIRRGHQVYTQVCSTCHSLNLISYRHLANVAYTPEELKAMAADTTVMDGPDSEGDMFERKGQVTDFHPKPYPNSNAARFANNGALPPDLSLVIKARGAHEDYVFSLLTGYCEPPAGVRVVGGQYFNPYFPGTKIAMAPPLADGMVEYDDGTDNSMSQMAKDVSTFLCWASEPEHDDRKKLGMKVLLGVSIIALPLFYWKRLKWSVIKTRKISFKD
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.  Cytochrome c1 is a catalytic core subunit containing a c-type heme.  It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c.
What are the official names of this protein?
Cytochrome c1, heme protein, mitochondrial, Cytochrome c-1, Complex III subunit 4, Complex III subunit IV, Cytochrome b-c1 complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YRAN_ECOSM
Sequence: MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVNERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RCANL_CAEEL
Sequence: MVADNSEKSTKSVANGSLISTVSSKDDLPNAIIVTQVPEDVFDNKQDKANFSSLFTQIEKDIHFDFLRSFRRVRVIFSSPENATAAKLIVQGFSFKGHELKAFFAQRIYMSANSQMLSPPPLEKQFLISPPCSPPVGWEQTKDMPPVVCNFDLMARLASFAIDEKYEVHNGDELTPAIIVHPCETPIDVPSAIEMPRTPRPSSPCEQ
What is the function of this protein?
Inhibits tax-6/calcineurin A phosphatase activity and thereby negatively regulates calcineurin-mediated functions (PubMed:12684004, PubMed:26232604, PubMed:27871170).  Plays a role in modulating temperature-dependent calcium responses in AFD neurons and in addition, also negatively regulates thermotaxis in a tax-6-dependent manner in AFD neurons (PubMed:26232604).  In response to changes in intracellular calcium levels may also regulate nuclear translocation of transcriptional regulators such as crtc-1 (PubMed:26232604).  May play a role in regulating body size (PubMed:27871170).  Plays a role in male tail tip morphogenesis (PubMed:21408209).
What are the official names of this protein?
Calcipressin-like protein, Down syndrome candidate region 1-like protein, Regulator of calcineurin.
What is the protein family that this protein belongs to?
Belongs to the RCAN family.
Protein: EPMA_YERPS
Sequence: MSDTASWQPSAPIANLLKRAAIMAEIRRFFADRGVLEVETPTMSQATVTDIHLVPFETRFVGPGAADGLTLYMMTSPEYHMKRLLAAGSGPIYQLGRSFRNEEAGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQILDCNSAETLSYQQAFLRHLNIDPLSAEKAQLREVAAKLDLSNIADTEEDRDTLLQLLFTVGVEPYIGRDKPAFIYHFPASQASLAEISTEDHRVAERFEVYFKGIELANGFRELTDGDEQLQRFEQDNRNRAKRGLPQNPIDMNLIAALKQGLPDCSGVALGVDRLVMLALNAERLSDVIAFPVNIA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: RUVA_BACLD
Sequence: MIEFVKGTIDYVSPQYIVIENGGIGYQIFTPNPFIYKKNSKETIYTYHYVREDTNALYGFSTREEKMLFTKMLNVTGIGPKGALAILASGDPGAVIEAIENEDEAFLVKFPGVGKKTARQIILDLKGKLADAVPEIAADLFNHEEREQIHEAATALEEALEALRALGYSDREIKKVQPHLKKEEALSTDQYVKKALQKLLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RPOB_LIBAF
Sequence: MRRNDGERHCVQWSRGARKFFGKNPEIIDIPDLIEVQKASYDQFLMMNTAPEDRPNEGLQAAFKSVFPIKAFSGAAMLEFVSYEFDPPKFDVDDCLRRDLTYAVPLKIILRLIVFDVDEFTGAKSIKDIKEQSIYMGDVPLMTKDG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: UVSSA_HUMAN
Sequence: MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQEMSGEIESCLTEVESCFRLLVPFDFDPNPETESLGMASGMSDALRSSCAGQVGPCRSGTPDPRDGEQPCCSRDLPASAGHPRAGGGAQPSQTATGDPSDEDEDSDLEEFVRSHGLGSHKYTLDVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQRFTRVGTHGGCLKRAIDLKAELELVLRKYKELDIEPEGGERRRTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAREQRRQLQKQERPEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN
What is the function of this protein?
Factor involved in transcription-coupled nucleotide excision repair (TC-NER), a mechanism that rapidly removes RNA polymerase II-blocking lesions from the transcribed strand of active genes (PubMed:22466610, PubMed:22466611, PubMed:22466612).  Facilitates the ubiquitination of the elongating form of RNA polymerase II (RNA pol IIo) at DNA damage sites, thereby promoting RNA pol IIo backtracking and access by the TC-NER machinery to lesion sites (PubMed:22466611, PubMed:32142649).  Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome (PubMed:22466611, PubMed:22466612).  Also facilitates transfer of TFIIH to RNA polymerase II (PubMed:32142649).  Not involved in processing oxidative damage (PubMed:22466612).
What are the official names of this protein?
UV-stimulated scaffold protein A.
What is the protein family that this protein belongs to?
Belongs to the UVSSA family.
Protein: ETF2_MCV1
Sequence: MYTVNPQLVVLVDRQQQLREVRYLSLYGTLDEASPLYYFAKQHLRAETLAVERRHILLTLKISQLKGYLCHLLGLREDIIIYSHKNNLEYSYVDNTIFNPFTMTQKKTLIKADSFLYNVYVDACDFLVVWVARAQDTPVPEFGSFEEVDANILKFEARLVEMFPELDLEFSIQSKFNNVFRTNLRSTGLRNIVKRNQDNRILFIKTDEFFITMSGNHFVLNNEALNLSIWDAQGRLAISSDGDTITVNDVRLFTELVTDSNLQMERIKGDITYRIFLLSPITSKIKLDIETSFIFVETATNNILLSADKKISIILAKNHISIKVKNHIPNIEKYFTFLVIFINRMFNAVQQAVDFTKIETIYWSRICQNTRDKNRKPVIVSSLDANMERVSDNFFRSPTREVFVNSNNIMFSCVDPLGKYNSVGFLAIFYKLQKMCIPCCFLRSQAHTDTFISCVHHRELDRQLVSPYVLNFGKIVTEAKISFLPILFDQFFNEGLRIEFEADHKRLKATDGYHVVKCCTRSEITRLRTQRDIIQFVNAEQNTLIAGDMVYFPMHGARSAGAEHQRVYILIQEIVHEVVMVQKAHDSDRIRFRELERNRLWEFFPYRVPSARIKEEHGLVLTTDGFYVDGKLFSEPLSTRYVAFTENVGTAGVAAKYFAPVFKYVVTEARELFIKTWLLNVMMQLGLTGESSAAQTREALERYYRLS
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa (RAP94) to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters (By similarity).
What are the official names of this protein?
Early transcription factor 82 kDa subunit, ETF large subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae VETF large subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: NADA_BACLD
Sequence: MSILKVIHDRNAGMMPEVYKELTEEEMAGRILKIKKKFGARLFIPGHHYQKDEVIQFADATGDSLQLAQVAQKNKKAEYIVFCGVHFMAETADMLTSDEQIVVLPDMRAGCSMADMANMRQTNRAWEELTKLFGDTVIPLTYVNSTAEIKAFVGRNGGASVTSSNAARMLTWALSQKERILFLPDQHLGRNTAFDLGIPLSRMAVWDPIAEKLEYNGDMKDIIIILWKGHCSVHEKFTVANIKSVKERDPDINVIVHPECTHEVVALSDFSGSTKKIIDSINEAKPGSKWAIGTEMNLVSRIIQEHPDKQIESLNPDMCPCLTMNRIDMPHLLWSLEQIDKGEPTGVIKVDQDIAKDAILALNRMLTIR
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG7_CANGA
Sequence: MTQKLLYVSPVESFVDTSFFQELSRLKLDIHGLSTSQITIHSYLDLKNIPSVSSACHLFLDQQSFNSEDICASSERVRLEGKLYNCNSLEEFKSLDKQQYLAEQGQKIYTKALEDINSAIGFSIISFADLKKYVFYYWVCTPLFQHENQQISILDGPEDIDASFNDKAKVWFTNHYSNWVAIVLENGDINEYTKGLNTSSIRGLLIRDTSNKQDMPSAFLRNFITIFSLDYPEAKELDVFLMRSSTIKSIKLRIRLSETEHTKLKFSGWERNSLSKLMPRAVDLSALIDPLKVAEQSVDLNLKLMKWRIAPELDLDCIRNNKVLILGSGTLGCYTARSLMAWGCRNITLVDNGRVSYSNPVRQPLFEFSDVGKEKAVAAAASLKRVFPLINAKGVQLDIPMIGHPVKDENNERKHFDALVDLIKSHDTMFLLLDSRETRWLPTLLGKFYDKIVMNAALGFDSYLIMKHGNIDDNFGCYFCNDVVVPTDSLTGRTLDQMCTVTRPGVAMLAASQAVELFVSNLQSRGQENVLGECPHQIRGFVNNFTTLKLQSPAYDNCSACSRHILNEYNKRGWDFVKQALNDNNYIEELSGLRRIKEEVENMELEGGEIKIIDSEDDGFEII
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.  Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine.  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: NU4C_PROM3
Sequence: MLEFAISAPLDTGAELLSDQVSANFPWLSLSILFPIVGAFLVPFIPDEGEGKQVRWFALGIALVTFVITVAAYLYGYDPSLSGLQLSERVSWLPDLGLTWAVGADGISMPLILLTSFITALAVLAAWPVTFKPKLFFFLILAMDGGQIAVFAVQDMLLFFLAWELELLPVYLLLAIWGGKKRQYAATKFIIYTAGSSLFILLVALAMGFFGGGTPNFEYTNLAQQSFGTGFQLLCYAGLLIAFGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALMRFNAQLLPEAHAQFAPLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFSALGTSGAMLQMISHGLIGASLFFLVGATYDRTHTLQLDEMGGVGQKMRIMFALWTVCALASLALPGMSGFVSELMVFVGFATDEAYTLTFRIVIAGLAAIGVILTPIYLLSMLREIFFGKENDQLVSHTNLVDAEPREVYIISCLLVPIIGIGLYPRLMTDSYTASIQELVKRDELALQRIKKPSALMIRNTTMTPAVVSSPRLPISQTRSEQLTRK
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, NAD(P)H dehydrogenase I, chain 4, NDH-1, chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: EFP_MICAN
Sequence: MISSNDFRSGTTIEIDGSVWRVVEFLHVKPGKGSAFVRTKLKNVQTGNVVERTFRAGETLPSATIEKRTMQHTYKEGDQFVFMDMETFEEATLTPVQMGDRAKYLKEGMEVNILFWNDQVLDIELPTSVILEITDTDPGVKGDTATGGTKPAIVETGAQVMVPLFISIGERIKVDTRDGSYLGRE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT102_YEAST
Sequence: MDPQTLITKANKVSYYGNPTSKESWRYDWYQPSKVSSNVQQPQQQLGDMENNLEKYPFRYKTWLRNQEDEKNLQRESCEDILDLKEFDRRILKKSLMTSHTKGDTSKATGAPSANQGDEALSVDDIRGAVGNSEAIPGLSAGVNNDNTKESKDVKMN
What is the function of this protein?
Probable component of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning.  RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA.  The reaction requires ATP and involves an activated RSC-nucleosome intermediate.  Remodeling reaction also involves DNA translocation, DNA twist and conformational change.  As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.  Probable component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
Regulator of Ty1 transposition protein 102.
Protein: BH056_ARATH
Sequence: MQFDESDARVWIWFEIRREDDIVELLWQSGQVVGTNQTHRQSYDPPPILRGSGSGRGEENAPLSQPPPHLHQQNLFIQEGEMYSWLHHSYRQNYFCSELLNSTPATHPQSSISLAPRQTIATRRAENFMNFSWLRGNIFTGGRVDEAGPSFSVVRESMQVGSNTTPPSSSATESCVIPATEGTASRVSGTLAAHDLGRKGKAVAVEAAGTPSSGVCKAETEPVQIQPATESKLKAREETHGTEEARGSTSRKRSRTAEMHNLAERRRREKINEKMKTLQQLIPRCNKSTKVSTLDDAIEYVKSLQSQIQGMMSPMMNAGNTQQFMPHMAMDMNRPPPFIPFPGTSFPMPAQMAGVGPSYPAPRYPFPNIQTFDPSRVRLPSPQPNPVSNQPQFPAYMNPYSQFAGPHQLQQPPPPPFQGQTTSQLSSGQASSSKEPEDQENQPTA
What are the official names of this protein?
Putative transcription factor bHLH056, Basic helix-loop-helix protein 56, AtbHLH56, bHLH 56, Transcription factor EN 106, bHLH transcription factor bHLH056.
What are the subcellular locations of this protein?
Nucleus.
Protein: COPD_HUMAN
Sequence: MVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTGKQHTFVETESVRYVYQPMEKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRENVNLAQIRTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQGKKAPGFGGFGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIMSSSMGKRTSEATKMHAPPINMESVHMKIEEKITLTCGRDGGLQNMELHGMIMLRISDDKYGRIRLHVENEDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVNSDVGVLKWRLQTTEESFIPLTINCWPSESGNGCDVNIEYELQEDNLELNDVVITIPLPSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVIDAKNKSGSLEFSIAGQPNDFFPVQVSFVSKKNYCNIQVTKVTQVDGNSPVRFSTETTFLVDKYEIL
What is the function of this protein?
Component of the coatomer, a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
What are the official names of this protein?
Coatomer subunit delta, Archain, Delta-coat protein, Delta-COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: GP59_BPT7
Sequence: MSRDLVTIPRDVWNDIQGYIDSLERENDSLKNQLMEADEYVAELEEKLNGTS
What is the function of this protein?
Plays a role in the inhibition of the host RecBCD complex (also called exonuclease V) (Probable).  A double mutation in this protein and the nucleotide kinase gp1. 7 protein allows phage to overcome the retron Ec48 bacteriophage defense system.  Overexpression of the wild-type gp5. 9 protein in E. coli with an intact Ec48 retron leads to a dramatic decrease in cell counts consistent with cell death, the L23P mutant does not have this effect (PubMed:33157039).
What are the official names of this protein?
Probable RecBCD inhibitor gp5.9, Gene product 5.9, Gp5.9.
Protein: ANOP_ANOSM
Sequence: GLLKRIKTLL
What is the function of this protein?
Antimicrobial peptide that exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria (PubMed:11738089, PubMed:15635634, PubMed:25530580).  Also shows antifungal activities (PubMed:24472551).  Exhibits potent activity in stimulating degranulation from rat peritoneal mast cells but not from RBL-2H3 cells (PubMed:11738089).  Has little or no hemolytic activity towards human erythrocytes (PubMed:15635634, PubMed:25530580).
What are the official names of this protein?
Anoplin, ANP, As-183.
What are the subcellular locations of this protein?
Secreted.
Protein: NUDK_YERPS
Sequence: MSVKIENIQCELLSKNWFKLHKYTFDLKTDEGTSVQQIREVYDRGNGATILLYNRQQGTVVLIEQFRMPTYVNGNASGMLLEACAGLLDNDSPEACIRREAMEETGYQVDKVQKLFEAYMSPGGVTELVYFFAAEYHPDQKITDEVGVEDEVIEVVELPFHDALAMVADGRIKDGKTIMLLQYAQIHFFPSSLTPQRC
What is the function of this protein?
Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.
What are the official names of this protein?
GDP-mannose pyrophosphatase, GDP-mannose hydrolase, GDPMK.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudK subfamily.