PharMolix/UniProtQA huggingface dataset:
Protein: ADT1_HUMAN
Sequence: MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (PubMed:21586654, PubMed:27693233).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).  In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (PubMed:31883789).  Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis (By similarity).  Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A4/ANT1 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity) (By similarity).  Proton transporter activity requires free fatty acids as cofactor, but does not transport it (By similarity).  Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1. 5 kDa, and which contributes to cell death (PubMed:31883789).  It is however unclear if SLC25A4/ANT1 constitutes a pore-forming component of mPTP or regulates it (By similarity).  Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 (By similarity).
What are the official names of this protein?
ADP/ATP translocase 1, ADP,ATP carrier protein 1, ADP,ATP carrier protein, heart/skeletal muscle isoform T1, Adenine nucleotide translocator 1, ANT 1, Solute carrier family 25 member 4.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: PSBA_SACOF
Sequence: MTAILERRESTSLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAALEVPSLNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CENPO_CHICK
Sequence: MEEERNSDEKENALCGRSLTAASRDGGGRMPAAPLAQGKVERGKVYSGDGVLGYLEMLEAQAHELGLKQEEKEQQEKKLDRLKARVQELRARRDELRAKVELQEKRLLDKEGVMTDPAQPSAQTVLEWKVKSLKAMLQVFYLTGISGKLTKQGVCFCISTAYEGTYLDSYYVDLLIKPLVKIQRHSVPVFIPLEQIAKKYLQTDIRRFLSVLSDHLNAYVGRRRQADQLEEHFSDHIDGTLQRNSLCNLLVFNYTVSSNSKTFPFNVRLLYGDLCCSLPTEAIISCTPGTLPLLAEMAAAHSNAFRHMALHKAFDSLINAKESQN
What is the function of this protein?
Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity).  Involved in kinetochore assembly and required for recovery from spindle damage.
What are the official names of this protein?
Centromere protein O, CENP-O.
What is the protein family that this protein belongs to?
Belongs to the CENP-O/MCM21 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres.
Protein: PRMA_CALS8
Sequence: MKWFEVAIKTVEEAEDAISNILYDLGANGVVIEDDEILKYPNSWDYIDENQFPKRNFAVVRAYFPESVNISELIFNIEERLKDASQYLNIGEGKIDISEVDEKDWANEWKKYYKPVEIGNIVIVPSWESYPNTKDKTVIKLDPGMAFGTGTHESTMLCLEAVQKYIKPGFDVIDIGTGSGILAIAAKKLGANRVLAVDIDDVAVKVARENAALNNVEIEIKQNDLVFGIEEKFDIAIANIIADIIIKLAKDIKNVLKEYGLFISSGIIEDRLDDVIKSFKENLLEVVEVKKLNNWCLVVARK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_SYNP6
Sequence: MRHRCNVPQLGRPADQRKALLRSLTTEIIRNGTVTTTKARAKAVRSEVERMVTLAKDGSLAARRQALGYIYDKQLVHLLFEQAPERYAKRQGGYTRILRTVRRRGDNAEMAIIELT
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL21_ALIF1
Sequence: MYAVFQSGGKQHRVSEGQTLRLEKLDVETGATVEFDNVLMIANGEEITVGAPLVAGGKVTAEVVQHGRGDKVKIVKFRRRKHSRKQQGHRQWFTEVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PRL_ONCMY
Sequence: MARRSQGTKLHLAVLCLVVSCHAIGLSDLMERASQRSDKLHSLSTSLTKDLDSHFPPMGRVMMPRPSMCHTSSLQTPKDKEQALKVSENELISLARSLLLAWNDPLLLLSSEAPTLPHPSNGDISSKIRELQDYSKSLGDGLDIMVNKMGPSSQYISSIPFKGGDLGNDKTSRLINFHFLMSCFRRDSHKIDSFLKVLRCRATKMRPEAC
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GRA1_CLAGR
Sequence: MTLPNNVVLFGDQTVDPCPIIKQLYRQSRDSLTLQTLFRQSYDAVRREIATSEASDRALFPSFDSFQDLAEKQNERHNEAVSTVLLCIAQLGLLMIHVDQDDSTFDARPSRTYLVGLCTGMLPAAALAASSSTSQLLRLAPEIVLVALRLGLEANRRSAQIEASTESWASVVPGMAPQEQQEALAQFNDEFMIPTSKQAYISAESDSSATLSGPPSTLLSLFSSSDIFKKARRIKLPITAAFHAPHLRVPDVEKILGSLSHSDEYPLRNDVVIVSTRSGKPITAQSLGDALQHIIMDILREPMRWSRVVEEMINGLKDQGAILTSAGPVRAADSLRQRMASAGIEVSRSTEMQPRQEQRTKPRSSDIAIIGYAARLPESETLEEVWKILEDGRDVHKKIPSDRFDVDTHCDPSGKIKNTSYTPYGCFLDRPGFFDARLFNMSPREASQTDPAQRLLLLTTYEALEMAGYTPDGTPSTAGDRIGTFFGQTLDDYREANASQNIEMYYVSGGIRAFGPGRLNYHFKWEGPSYCVDAACSSSTLSIQMAMSSLRAHECDTAVAGGTNVLTGVDMFSGLSRGSFLSPTGSCKTFDNDADGYCRGDGVGSVILKRLDDAIADGDNIQAVIKSAATNHSAHAVSITHPHAGAQQNLMRQVLREGDVEPADIDYVEMHGTGTQAGDATEFASVTNVITGRTRDNPLHVGAVKANFGHAEAAAGTNSLVKVLMMMRKNAIPPHIGIKGRINEKFPPLDKINVRINRTMTPFVARAGGDGKRRVLLNNFNATGGNTSLLIEDAPKTDIQGHDLRSAHVVAISAKTPYSFRQNTQRLLEYLQLNPETQLQDLSYTTTARRMHHVIRKAYAVQSIEQLVQSLKKDISSSSEPGATTEHSSAVFLFTGQGSQYLGMGRQLYQTNKAFRKSISESDSICIRQGLPSFEWIVSAEPSEERITSPSESQLALVAIALALASLWQSWGITPKAVMGHSLGEYAALCVAGVLSISDTLYLVGKRAQMMEKKCIANTHSMLAIQSDSESIQQIISGGQMPSCEIACLNGPSNTVVSGSLTDIHSLEEKLNAMGTKTTLLKLPFAFHSVQMDPILEDIRALAQNVQFRKPIVPIASTLLGTLVKDHGIITADYLTRQARQAVRFQEALQACRAENIATDDTLWVEVGAHPLCHGMVRSTLGLSPTKALPSLKRDEDCWSTISRSIANAYNSGVKVSWIDYHRDFQGALRLLELPSYAFDLKNYWIQHEGDWSLRKGETTRTTAPPPQASFSTTCLQVIENETFTQDSASVTFSSQLSEPKLNTAVRGHLVSGTGLCPSSVYADVAFTAAWYIASRMTPSDPVPAMDLSSMEVFRPLIVDSNETSQLLRVSATRNPNEQIVNIKISSQDDKGRQEHAHCTVMYGDGHQWMEEWQRNAYLIQSRIDKLTQPSSPGIHRMLKEMIYKQFQTVVTYSPEYHNIDEIFMDCDLNETAANIKLQSTAGHGEFIYSPYWIDTVAHLAGFILNANVKTPADTVFISHGWQSFQIAAPLSAEKTYRGYVRMQPSSGRGVMAGDVYIFDGDEIVVVCKGIKFQQMKRTTLQSLLGVSPAATPTSKSIAAKSTRPQLVTVRKAAVTQSPVAGFSKVLDTIASEVGVDVSELSDDVKISDVGVDSLLTISILGRLRPETGLDLSSSLFIEHPTIAELRAFFLDKMDMPQATANDDDSDDSSDDEGPGFSRSQSNSTISTPEEPDVVNVLMSIIAREVGIQESEIQLSTPFAEIGVDSLLTISILDALKTEIGMNLSANFFHDHPTFADVQKALGAAPTPQKPLDLPLARLEQSPRPSSQALRAKSVLLQGRPEKGKPALFLLPDGAGSLFSYISLPSLPSGLPIYGLDSPFHNNPSEFTISFSDVATIYIAAIRAIQPKGPYMLGGWSLGGIHAYETARQLIEQGETISNLIMIDSPCPGTLPPLPAPTLSLLEKAGIFDGLSTSGAPITERTRLHFLGCVRALENYTVTPLPPGKSPGKVTVIWAQDGVLEGREEQGKEYMAATSSGDLNKDMDKAKEWLTGKRTSFGPSGWDKLTGTEVHCHVVGGNHFSIMFPPKVC
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of orcinol depsidone grayanic acid (GRA), the only major secondary metabolite known in C. grayi (PubMed:21289108).  The first step consists in the ring and depside synthesis by PKS16 leading to 4-O-demethylsphaerophorin, involving different orcinol-like rings, one with acetyl CoA and the other with octanoyl CoA as the starter (Probable).  Further depsidone formation by the GRA cluster-specific cytochrome P450 leads to 4-O-demethylgrayanic acid (Probable).  Finally, the cluster specific O-methyltransferase probably converts the 4-O-demethylgrayanic acid into grayanic acid (Probable).
What are the official names of this protein?
Non-reducing polyketide synthase PKS16, NR-PKS PKS16, Grayanic acid biosynthesis cluster PKS.
Protein: PSBF_YUCGL
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ZAPD_ENT38
Sequence: MSSHILFEHPLNEKMRTWLRIEFLIQQMSFHLPIAEHATALHFFRNVGDLLDVIERGDVRTELLKELERQQRKLQGWAEVPGVDQNRIDSIRLQLKQSSTILMAAPRVGQFLREDRLIGLVRQRLSIPGGCCSFDLPTLHIWLHMSQEQRDAQVKNWMGSLEPMNQALTLILDLVRNSAPFRKQTSLNGFYHDNGDDADLLRLQLSLGDQLYPQISGHKSRFAIRFMPLDSENGSVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: ATPA_RUEPO
Sequence: MGIQAAEISAILKDQIKNFGQEAEVAEIGRVLSVGDGIARVYGLDNVQAGEMVEFPGGIMGMALNLENDNVGVVIFGSDRDIKEGDTVKRTNSIVDVPQGDELLGRVVDGLGNPIDGKGPINAKLRGVADVKAPGIIPRKSVHEPMATGLKAVDSMIPIGRGQRELIIGDRQTGKTAIALDTILNQKSYNDAAGDDESKKLYCVYVAIGQKRSTVAQLVKKLEENGAMEYSIVVAATASDPAPMQFLAPYAATAMAEYFRDNGRHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLNEDFGAGSLTALPVIETQGGDVSAFIPTNVISITDGQIFLETELFYQGIRPAVNTGLSVSRVGSSAQTKAMSSVAGPVKLSLAQYREMAAFAQFGSDLDAATQQLLNRGARLTELMKQPQYSPLTNAEIVCVIFAGTNGYLDKVALADVGRWEAGLLQHLRGKHAELLAWITNEDPKIKDDAAGRVKAALDEYAATFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEPA_CAMLR
Sequence: MKNIRNFSIIAHIDHGKSTLADRIISECGAISDRLMSNQVMDTMDIEKERGITIKAQSVRLNYKFNNEEYVLNLIDTPGHVDFSYEVSRSLASCEGALLVVDASQGVEAQTIANVYIALENNLEIIPVINKIDLPSADIEKVKHEIEHIIGIDCSSAICVSAKTGVGIKELIETIITKIPAPKTNDEAPTKALIYDSWFDNYLGALALVRVYEGNIAKNEEVLIMSTDKRHIVQDLFYPHPLSPIKTKKLESGEVGVIVLGLKNVADVQVGDTITLTKNKAKEAIGGFEKAKAFVFAGLYPIETDKFEDLRDALDKLKLNDSSITYEPETSLALGFGFRVGFLGLLHMEVIKERLEREFNLDLIATAPTVTYEIYQTDGEILKIQNPSELPPVNKIDHIKEPYVKATIITPSEYLGNLITLLNRKRGMQVKMDYITPERVLLEYDIPLNEIVMDFYDKLKSLTKGYASFDYEPIEFRVGDLVKLDIKVAGENVDALSIIVPNEKALSKGRELVKAMKEIVPRQLFEVAIQASIGNKIIARENVKSMGKNVTAKCYGGDITRKRKLLEKQKEGKKRMKAIGKVHLPQEAFLSVLKID
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MNMG_RHIEC
Sequence: MTNSGYNVIVIGGGHAGTEAASAAARLGAKTALVTHRRDTIGVMSCNPAIGGLGKGHLVREIDAMDGLMGRVADVAGIQFRMLNRKKGAAVRGPRTQADRKLYRLAMLAAIEATPGLDIIEGDAFDLDVLDGRVAGVIMKDGRRLQAPAVVLTTGTFLRGLIHIGSEKTPAGRVGEAPSIGLSATLARLGLRLGRLKTGTPARLDGKTIDWQSVGRQGADEELVPFSFMTDSITTRQVECGVTRTTEATHRIIVDNIKHSAMYSGQIEGVGPRYCPSIEDKLVKFGERDGHQVFLEPEGLDDDTVYPNGISTSLPAEIQAAFIKTIPGLESARILQPGYAIEYDHVDPRELTPSLEVKRLRGLFLAGQINGTTGYEEAAAQGLAAGLNAALLSSDSEPFHFSRTSSYIGVMIDDLTSRGVTEPYRMFTSRAEYRLTLRADNADMRLTPLAMALGCVGAERAERFTAYQAEIDAGRAQLMALTVTPNEARRAGLNINLDGQRRSAYDFLSYPTYDFAALRKVWPEELGRLRPKVAEALEIEAGYSVYLDRQAAAIADQQRDEERRIPADFNYDALSGLSNELKAKLSAARPFNVAQAAIVEGMTPAAVALLLVHLRRQQGFERQSADTRSESL
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_GEOSM
Sequence: MTTPVLNTDFPGLKLAARGKVRDIYDLGETLLIVTTDRISAFDVIMNEGIPHKGYVLTQISAYWFRQMEGIIKNHIISTDVADFPKECQPYADVLAGRSMWVKKAQPLAAECIVRGYISGSGWKDYQSTGAICGIKLPEGLKESDRLPQPIFTPSTKAELGTHDENISFEEMCRICGTEISTKVRDVTLAIYEKARDIADQKGIIIADTKFEYGIYEGELIIIDECMTPDSSRFWPKDSYKPGGPQPSFDKQFLRDYLETLDWGKTAPAPPLPEEIVRKTGEKYMEALVKLTGKGI
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RS3A_PLAF7
Sequence: MAVGKNKRTSKGKKGGKKKVTDVFTKKEWYDLKAPKMFLVRNFGKTLVTKTIGKKLATDSLKGRIYEVNLADLNNDEDQAHKKIKLSCDHIINRDCYTDFCGLSITRDKLCSLIRKGYTLIEGHTDVKTLDNYHLRMFCIAFTKKRQNQTKSTCYAQTSQIKKIRKKMVDIMTAEASKVLLKDLVKKFIPESIGKEIEKQCKKIYPLQNVLIRKVKILKRPKLDISKLMELHTDPKEESGKNVNALPESKEATNILTAELKH
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (Probable).  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable).  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable).  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable).
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_SALTY
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_THEP1
Sequence: MPKREDIKRILVIGSGPITIGQAAEFDYSGTQALKALKSAGYEVIIVNSNSATIMTDPEFSDAVYIEPLTVEFLEKIIEKERPDALLPTLGGQTALNLAVELAERGILDKYGVQLIGAKLESIKKAEDRELFKETMEKAGLEVLRSRLVNNLADALETAREFGYPVIIRPSFTLGGTGGGIAFNEEELRDIVTKGLIESPVHTVLIEESVLGWKEYELEVVRDGAGNFIVVCSIENLDPMGIHTGDSITVAPAQTLTDVEYQRMRDAAYKVIDAIGIETGGSNIQFALDPETGRMVVIEMNPRVSRSSALASKATGYPIAKVAALLAVGFTLDEIPNYITGKTMAAFEPSIDYVVVKIPRFQLEKFPGADPRLNTQMKSVGEVMAIGRTFKEALGKALRSLELDAAPKLDLEHIREHLANPTPERISYVFAAFRNGMDVEEVHELTKIDRWFLREMKACIELEEELKLKKFDVEILKKAKQWGYSDREIAEIWGVSEKEIRKMREDNRIFPVYKMVDTCAAEFEAQTPYYYSTYNGVENEAVPSDREKIMILGSGPNRIGQGIEFDYTNVHGVWSFQEEGYETIMVNSNPETVSTDYDTSDRLYFEPLTVEDVLEIVRNEKPKGVVVAFGGQTPLKIAKYLVEEKVNIIGTSFESIEIAEDREKFAKLLKQIGLKCPPFGTASSVEEALRVAENLGYPVLVRPSYVLGGRAMAIVDTPQELEMYVKEAAVVSPGYPVLIDKFLEDAIELDVDVVSDGKYVWIAGLMEQIEEAGVHSGDSACVLPPVSLSEKLVEEIEETVYKLVKALKIVGVANIQLAVKDEEIYIIEANPRASRTVPFVSKAIGIPVARIAAKIMVGRNLPELLSEYFPYPTRPGVKVDKLDESEILPTPWPKMFSVKEVVIPFHKFPGTDVLLGPEMRSTGEVMGIGEDFAEAFAKAQIAAGNPLPTTGAILATVADKDKREAVPLLAHLADMGFEIYATRGTAKALQSHGVEVKVVPKVGEGRPDVIDLLEQGKISLVVITQSSDEPALVAVSHGKEPFKVEGRRTVGYMIRTTALKRKIPYLTTVESLRAAVAAIRKMKKGSIVKVRRLTDTWKM
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: AMPS4_LITPI
Sequence: KPKEDKEWVKFKAKHITSQSVADFNCNKTMNDPDFTPDGQCKPVNTFIHSNTGPVKDICRRASGRVNKSSTQQFPLTTCNKPIRCKYSQSNTTNFICITCRDNYPVHFVKIGKC
What is the function of this protein?
Endonuclease, hydrolyzes highly polymerized RNA, poly(U) and poly(C), and the dinucleotides CpA and UpA.  Hydrolyzes rCA, rUA and rUG.  Has cytotoxic activity against cultured human submaxillary gland carcinoma cells.
What are the official names of this protein?
Amphinase-4.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL18_PROM4
Sequence: MATLSKKQQTQKRHKRLRRHLNGTNHRPRLAVFRSNNHIYAQVIDDEAQSTICSASTLDKDLREKLKASGGSCDASMAVGALLAQRALAKGIEQVVFDRGGNLYHGRVKALAKSAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HSD_MYCTO
Sequence: MSGRLIGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAVAAELADAARYVHLDVTQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPGGIRVNSIHPGLVKTPMTDWVPEDIFQTALGRAAEPVEVSNLVVYLASDESSYSTGAEFVVDGGTVAGLAHNDFGAVEVSSQPEWVT
What is the function of this protein?
Probably involved in steroid metabolism.
What are the official names of this protein?
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ISPT1_TROW8
Sequence: MGGKMLRSVSELIYKVYARYLLGQINLNNLPGHVALIVDGNRRWARKEKRDRISDGHRAGAGKAVDFLHWCDELDINIVTLYLLSNDNLKNRNRQELNDLVQVICNLIAQVSKRWKVNHVGSCENLPELLGNSLEGVKSSTKTNRYSERSMTVNLAIGYSGRAEITEAVRKIVNTYPIGDLPEKITEEVISANLYTGGLSDPDLIIRTSGEQRLSDFMPWQSTHSEFYFLEALGPDLRKVDFLRAIRDFSIRRRSFGA
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: Y565_METJA
Sequence: MDIKNMRNVIVSLSLVFGLLFTVSGIIEIIIGLYSILGFKIELPLFVGDVFGGLALLAVGIAYFLGVKKAVDRDIKAVSYLFTASIIGLGIGVIAFLILISDAIGFLLGFEDWADWGFFNDLTVYLVLGMLAIIPYRIAKIISSSTT
What are the official names of this protein?
Uncharacterized protein MJ0565.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1846_THIDA
Sequence: MPSFDIVSEVDKQEVRNAIDQVNKEVSTRFDFKGSDARVEQSDYALTVYADTDFQLDQVQDILSQKLSKRGVDVKCLDTGNVEKVSGNKVKRSVTVKTGVGTELAKKIVKCIKDSKLKVQASIQGETVRVSGAKRDVLQETIALVKKSVSDFPLQYQNFRD
What are the official names of this protein?
UPF0234 protein Tbd_1846.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: HSLV_STACT
Sequence: MNNSIHATTIFAIRQNGHAAMAGDGQVTLGEQVIMKQTARKVRRLYDGKVLAGFAGSVADAFTLFEKFETKLQEFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKNSILVVSGTGEVISPDDDLIAIGSGGNYALSAGRALKRHTEMSAKDIAYASLKVASEICVFTNDNIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_AGRRK
Sequence: MRCPYCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTFERVQLRELMVIKKTGRKVLFDRDKLVRSFEIALRKRPVDRDRIERAVSGIVRRLESSGETEISSEQIGLQVLEALKSLDDVAFVRYASVYRDFSHAEDFENVITEINAKIARDPLDP
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL19_CAMLR
Sequence: MKNKYIEQFEQKQIEGKNVPEFRAGDTLRLAIRIKEGDKTRIQNFEGICIARRGNGVDETFIVRKIGANNVGVERIFPIYSESLESITVLRRGRVRRARLFYLRDRRGKAARIKELKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL13_ECOLC
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.