PharMolix/UniProtQA huggingface dataset:
Protein: ENO_EDWI9
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVSAVNGPIAEVIIGKDAKDQANIDQIMIELDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYAHIAELNGTPGKYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRIGSEVFHNLAKVLKSKGMNTAVGDEGGYAPNLESNAAALAAIKEAVEKAGYVLGKDVTLAMDCAASEFYNKETGMYELKGEGKSFTSNEFTHYLEGLTKEYPIVSIEDGLDESDWDGFAYQTKVMGGKLQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGAAAPFNGLKEVKGQH
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ERO12_SCHPO
Sequence: MKIAKGLVGLLILYKNVCQVLCKSGSSVKSGSPWSIKNDGKSIIHDTLNSSYSDIENLNSRVSPLLFDLTEKSDYMRFYRLNLFNKECRYNLDDNVACGSSACNVLVTDEQDVPEVWSSKSLGKLEGFMPELSRQIVETDRSVMEHVDKISQSCLLERLDDEAHQYCYVDNELDSGCVYVSLLENPERFTGYSGPHSTRIWEMIYNQCLPDSSAPTIDFPALFMQGPLAPPPKPQEQLLKERMDAWTLEQRVFYRVLSGMHSSISTHLCHGYLNQRNGVWGPNLQCFQEKVLNYPERLENLYFAYALMQRAIDKLYGHLDSLTFCHDSVLQDSEVRQKIAGLVSLIHNSPKMFDETMLFAGDPSISTALKEDFREHFKTVSALMDCVGCERCRLWGKIQTNGFGTALKILFEVSNIEDEVTNFDSRSFSLRLRRSEIVALINTFDRLSRSINFVDDFKQIYSEQHKPASFKRRVLRRIKQLLFSVTPVALHPFLQKTSSILVDLYFDFKAEWDNVMLGFRYVFASYLRFPRLFKFVLFSQESPFLNWTSHHLQRYIPKNWFPEVASV
What is the function of this protein?
Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds.  Acts by oxidizing directly pdi1 isomerase through a direct disulfide exchange.  Does not act as a direct oxidant of folding substrate, but relies on pdi1 to transfer oxidizing equivalent.  Does not oxidize all pdi related proteins, suggesting that it can discriminate between pdi1 and related proteins.  Its reoxidation probably involves electron transfer to molecular oxygen via FAD.  Acts independently of glutathione.  May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress.
What are the official names of this protein?
ERO1-like protein 2, Endoplasmic reticulum oxidoreductin-1-like protein B.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: BTUCA_HALSA
Sequence: MREASARAVAWSAAAGVLLVAVLLVSATIGPEPITLRTVAMAALTELAVPVGASVTMHTHAVPVVSGGLPWPALTIAYAAPLQFGVPETAQVIVGTIRLPRIVLGATVGASLAISGAVLQGFFRNPMADPSIVGVSSGAAVGAVAAITLPSVVVIGVQPAAFAGALIAAFTVYAIATKNGHTPTATLLLSGVAVQTLLGAVTSFLVVNSGREIRPAMYWLMGTLHGSRWHDVEAALPVVVVGSAVLLAYAREMNVLLAGEEDAHTLGVDVDRTKRLLLAVASVVTAAAVSFAGAIGFVGLIVPHAVRLVVGPDHRVLLPVSALTGGAFLVAADTVARATATEPPVGIITALIGAPFFLYLLRDREVRAL
What is the function of this protein?
Required for corrinoid utilization.  Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import.  Probably involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Cobalamin import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATL_THET8
Sequence: MWLPTPLGPLWLEVSPLGVRRLEPALYPRGPEAEGALALRVREAVQAYFAGERPDFLDLPLDYTGLSPARLRLYERVRLVPYGRTVSYGALGRELGLSPRAVGAALRACPFFLLVPAHRVIHADGRLGGFQGQEGLKLWLLRFEGAL
What is the function of this protein?
Involved in DNA damage recognition.  Binds DNA containing O(6)-methylguanine and larger O(6)-alkylguanine adducts (PubMed:18483064, PubMed:23112169).  Binds to the damaged base and flips the base out of the DNA duplex into an extrahelical conformation, which allows processing by repair proteins (PubMed:18483064).  Also affects the regulation of gene expression in response to alkylation (PubMed:21531768).
What are the official names of this protein?
DNA base-flipping protein, Alkyltransferase-like protein ATL.
What is the protein family that this protein belongs to?
Belongs to the MGMT family. ATL subfamily.
Protein: GCH4_PSEPF
Sequence: MNALTLPDVAAQAARQALPLEWVGMCGIALPVFIEGQRLAAKADAGVSLDDGDARGIHMSRLYLGLEAMEQQNLSPALLRQVLQRFLDSHEDLSEAAYLNIHIDLLLRRPALVSPLAGWKNYPVTVSAQLKNKVFHVELKIDVAYSSTCPCSAALARQLIQQQFVDDFANKPLQHADVLAWLGSTQGIVATPHSQRSTAQLHLHLDEFVDELPLTSIINDAEAALGTAVQTAVKRADEQAFALANGQNLMFCEDAARRLNLALRGSPGISQFHVRVIHAESLHAHDAVAESHWRREQP
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RHB1_SCHPO
Sequence: MAPIKSRRIAVLGSRSVGKSSLTVQYVENHFVESYYPTIENTFSKNIKYKGQEFATEIIDTAGQDEYSILNSKHSIGIHGYVLVYSITSKSSFEMVKIVRDKILNHTGTEWVPIVVVGNKSDLHMQRAVTAEEGKALANEWKCAWTEASARHNENVARAFELIISEIEKQANPSPPGDGKGCVIA
What is the function of this protein?
Regulates entry into stationary phase when extracellular nitrogen levels are adequate for growth.
What are the official names of this protein?
GTP-binding protein rhb1, GTP-binding protein Rheb homolog.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rheb family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: PEBB_SYNS9
Sequence: MTTTRHSSTDSVNIPGWGWQPFLEDAVQALQPLNLEPYPVANDFLYKQDQTGSKAKPITVTTATWACKTDKFRQVRAACVYGGTAASVLNFVINPSARFDLPFFGGDLVTLPSGHLLALDLQPADKSDEAHTQQVWEKLIPIFERWRSKLPDGGPIPEEAQPFFSPGFLWTRLPLGDEGDQLINSVVRPAFNDYLSLYLELAEAAKPVGDDRRDHLLKGQRRYTDYRAEKDPARGMLTRFHGSDWTEKYIHTVLFDL
What is the function of this protein?
Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin.
What are the official names of this protein?
Phycoerythrobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: ATP6_BALMU
Sequence: MNENLFAPFMIPVMLGIPITTLIIILPSILFPAPNRLINNRTISIQQWLTKLTSKQLMSVHSPKGQTWSLMLISLFLFIASTNLLGMLPHSFTPTTQLSMNVGMAIPLWAGTVATGFRNKTKMSLAHLLPQGTPTFLIPMLVIIETISLFIQPVALAVRLTANITAGHLLMHLIGETTLVLMSTSLFTAIITFTILALLTILEFRVALIQAYVFTLLVSLYLHDNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VSSGP_EBORR
Sequence: MGSGYQLLQLPRERFRKTSFLVWVIILFQRAISMPLGIVTNSTLKATEIDQLVCRDKLSSTSQLKSVGLNLEGNGIATDVPSATKRWGFRSGVPPKVVSYEAGEWAENCYNLEIKKSDGSECLPLPPDGVRGFPRCRYVHKVQGTGPCPGDLAFHKNGAFFLYDRLASTVIYRGTTFAEGVVAFLILSEPKKHFWKATPAHEPVNTTDDSTSYYMTLTLSYEMSNFGGNESNTLFKVDNHTYVQLDRPHTPQFLVQLNETLRRNNRLSNSTGRLTWTLDPKIEPDVGEWAFWETKKKLFPTTSWRKLAFPNSINPHQQLLRSEPGGNCPRKN
What are the official names of this protein?
Super small secreted glycoprotein, SsGP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCPB_ACET2
Sequence: MDLKKLEGIFEGMLFASGDKVSIEKLSSITGIDKKTVKLVINNMIVKYNNDPSRGITIREINNGYQLCSKPEYYDYIKQLFEPKQRSGLSQAALETLAIIAYNRPITKAKIEQIRGVNSDSAITKLLEKNLIREAGRLDAPGKPVLYETTDEFFRSFGFKSDADLPIFELNDIHETVEINQNSEQEKADTELEKQEKA
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: IAP_ASFM1
Sequence: MFPKINTIDPYISLRLFEVKPKYVGYSSVDARNQSFAIHDIKNYEKFSNAGLFYTSPTEITCYCCGMKFCNWLYEKHPLQVHAFWSRNCGFMRATLGIIGLKKMIDSYNDYYNNEVFVKHKNRVYTHKRLEDMGFSKPFMQFILANAFIPPYRKYIHKIILNDRYFTFKFAAHLLSFHKVNLDNQTTYCMTCGIEPIKKDENFCNACKTLNYKHYKTLNFSVKL
What is the function of this protein?
Prevents apoptosis of host cell by inhibiting caspase-3/CASP3 activation to promote the viral replication.  Induces also the activation of host NF-kappaB.
What are the official names of this protein?
Inhibitor of apoptosis protein, IAP.
What is the protein family that this protein belongs to?
Belongs to the asfivirus IAP family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Probably accumulates in the perinuclear cytoplasmic viral factories. Found in association with viral nucleoid.
Protein: PSBJ_SACOF
Sequence: MADTTGRIPLWLIGTVTGILVIGLIGVFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUSB_ACIBS
Sequence: MYQTLQAAYAAKRKARRFAVQGIYEWQMSHNPVHEIEARTRAENAMHKVDLNYYHELLTQVIAQHEDLDALLIPVLDREIDALDGVELATLRLGAYELRDHLEIPYRVVLDEAIELAKHFGGADSHKYINGVLDRLSSTLRSAEKQQAK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SYP_CERS5
Sequence: MRLSRYFLPVLKENPSEAQIVSHRFMLRAGMIKQQAAGIYSWLPLGFKALKRVEQIVHEEQIRAGHIPLLMPTLQPADLWRESGRYDDYGEEMLRITDRHKRDMLYGPTNEEMITDIFRSHVNSYKDLPLTLYHVQWKFRDEIRPRFGVMRGREFLMKDGYNFDLDFDSAIHAYNRHMVSYLRTYERMGLQAIPMRAASGPIGGDNTHEFLVLASTGESEVFYDAAITDLKFGDRVVDYDSREECEAIVKEWTTPYARTDETHDEAIFNAIPEERRRTSRGIEVGQIFYFGTKYSEPMGATVVTADGARVPVHMGSHGIGVSRLLGAIIEASHDDKGIIWPEGVTPFHVGIVNLKQGDSSTDLACEALYRDLSAKGLEPLYDDRDERAGAKFATMDLIGLPWRITVGPRGIAAGKVELTNRRTGESEEMSSGAAVDRLAQIYAGI
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAHO_RAT
Sequence: MAVAYYCLSLFLLSTWVALLLQPLQGAWGAPLEPMYPGDYATHEQRAQYETQLRRYINTLTRPRYGKRDEDTAGLPGRQLPPCTSLLVGLMPCAAARS
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide prohormone.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANC_THEAB
Sequence: MKVIEKIEEMKKISREILESKKAIGFVPTMGFLHEGHLSLVKAAKSENDITVVSIFVNPTQFGPNEDYNNYPRDLERDLSMLKDMEVDYVFVPSVEEMYPDSFSTYVEEIKLSRFLCGASRPGHFRGVCTVVTKLFNIVKPTRAYFGQKDAQQFRVLRRMVRDLNMDVELVEMPIVREPDGLALSSRNTYLNDEERKEAVRLYKSLLKAKELIESGEKDVEIIKNEMKKILTHPLLRIDYIEIVDEENLEPVEKIDRRVIIAIAVFVGRARLIDNMII
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_EHRCR
Sequence: MEHKDNSTMYGTTILCIRRGNKVIIAGDGQVSLGHTVIKNSAKKIKRLANDTVITGFAGATADAFTLFERLESKLEKHPGQLLRACVELAKDWRMDRYLRRLEAMMIVADKSVSLIISGNGDVLEPENGIAAIGSGGNYALAAAKALCESNDQFSQNMTLEYIITTAMKIASEICIYTNNNIIMEKIED
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTC6_CANDC
Sequence: MIGLLFVFSVLLSFSVGYIFPFSTSNGPTVNDTLQHAIRSQRDVSKPIPIDRVEFSGVSLSSFFESEGYSSDSLSNLYGLLKENIAGVMIDLYWNEFTSKWQLCPAPFPNNITYTSSNRVVDVSWNNRTYKCDPNLSTDDIMSILNNFIRDTNTDVEANFMHVMYNLKSIHYKKSNQTINLENAYKEKNSNFNVGMDTLNDTVSLLSSYIFTPLLLEQYQSSSSKNANSSSSIRYIDSLNETQAIQKFYNQSTILMPSLQTTLLTQYKRLMVHVISNDMAESSRSYQISFSDKETIFFNNVFPAMIGHTNNASADDFCYELTHAYNGTDVNIMEFNRVSLNSTLRLIIDNDKTPFTTDSLSKYVRCGYCPVFNSTQYSSQKVTEGNSSIISQEFTSNLFWSWAPGQPSGPDNCTNCTRPVTNYTSKYSEASNGGSDEEEHSNNIAYKCVALTENGWEVSNCYEKYLFACQNKLSRNEWKLDNYTKRNYFDLDDDDCPEGYFFSLPRSNIEMLSLMTTVKQENVSYPIWIDLNDITVENCFVSGGPYAQCPYQETVTTDKFVRMIAPSFVVAMVVLVLIFLEKVFRKTPIQTNRKRYWKKAIQEYYAKNDYEGVPS
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 6.
What is the protein family that this protein belongs to?
Belongs to the MTC6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TIM22_CANGA
Sequence: MVYRGFGLEYLSPPEKKAFGELSPDEQGERGAEMVVGFMSSCPGKSVISGATGFALGGVLGLFMASMAYDTPLHTPVPGGMSGAVQQMADLPLRQQVKLQFADMGKRAYSSAKNFGYIGMIYAGVECAVESLRAKNDIYNGITAGCITGGGLAYKSGPQAALVGCAGFAAFSAAIDMYMKSEDGRPPENDFKQ
What is the function of this protein?
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel.  Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM22.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PUX1_ARATH
Sequence: MFVDDPSLHTLKRRRLEITDSMEASSSAQAKIADMREKLGREVRVFETSSISQRPSQVSSADDESDDFYEFTPADFYRLLATKKEDKSLKTRKIREAEEAARRSKLTKAVIRVRFPDNHTLEATFHPSEKIQGLIDLVKRVVAHPDVPFYLYTTPPKKQIKDFSQDFYSAGFVPGAIVYFSNDQPKDDGGSSTPYLNEEILSLKDLEAMTKAVEPVESSSEPATVDSSAVPVEHERKSTEKKTTKPKWFKM
What is the function of this protein?
Regulates CDC48A by inhibiting its ATPase activity and by promoting the disassembly of the active hexamer.
What are the official names of this protein?
Plant UBX domain-containing protein 1, PUX1, CDC48-interacting UBX-domain protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U16_HHV6G
Sequence: MADERTGDSVKTRYDIALMNLNDIKIAVFRDSLSTYVEQKTGLTIQFNWPKSRCLVISTLCKIPFPTKSAAELQEMCSLLLCCPERLQLLGYVSVWGEETRDVCLTKTLVFAGEDEKFYGLDFVNETLYLLAETTERFAVLGLRRYDPVYREKDIRFLTKIDDVLQSLIDAQDNLWKFATIVYKNSGRHYIMKSCLENNDGVFVLFLTRKEDFPSRMEWNFFSDVYESMPYHGQVIGSIGKTLLYPKTMFVMMDLSGAIYGIDTIGTGIGSCVKIADDFESFLRQGIVRGYRRYKFFHRNISTVQEILPLCPHTSLGPTFSNNYNYDLSSEDDE
What is the function of this protein?
Isoform 3 can transactivate the human immunodeficiency virus type 1 promoter.
What are the official names of this protein?
Protein U17/U16.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: LEUD_PYRAE
Sequence: MKIRGRALVYGDKIDTDVIIPAKYLVYTDPALLGQHAMEPLDPEFPKKAKGAVLVAGRAFGMGSSREQAALALKGAGVLAVVAESFARIFFRNAINVGLPVLQAPGIREKVKDGDEVELDVEGGIVRNITTGEVIVGKPLRGLPLEILKAGGLLNYLKNSR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: IDI_SALTY
Sequence: MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDGQLLVTRRSLSKKAWPGVWTNSVCGHPQQGETTEEAIIRRCRFELGVEITDLTPVYPHFSYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWKSLLATPWAFSPWMVMQASDEQARERLLNYCQR
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_BORA1
Sequence: MNTLRFPAGLYGVTPEWDDTSRLLAAVRDAAAGGMRALQLRRKHLSREQRLLQARALAPLCRELGVTFIVNDDWRTALEAGADGAHIGRDDATLAEVRAAAPGLLLGVSCYADLNRARELLAQGADYIAFGAVFPSPTKPQAAHAPLALLGEAAAQVRACGEPRPAVVAIGGITPANAGLVAAAGADSIAVITGLFEAPDIRAAAQACAAPFPLTD
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: TSAC_SHEHH
Sequence: MLEVLPADVAELVEQGGVIAYPTEAVYGLGCDPDNDDAIERLLEIKLRPWQKGLILVAGDYQQLLPYIDESQLSAEQLAFVHSKWPGPFTFIMPVKPGLSNLLSGSFDSIAVRVTAHEGVKALCAAINKPIVSTSANLTGQDPALSGAAVKQQFEGIIAGLVIGDLGIQASPSTIIDAKSGQVIRKG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RASE_MOUSE
Sequence: MALPTKSSILDLSSGTPCTRSPEESHEAWAQCKDAGRQLPEYKAVVVGASGVGKSALTIQMTHQCFVKDHDPTIQDSYWKEVARDNGGYILNVLDTSGQDIHRALRDQCLASGDGVLGVFALDDPSSLDQLQQIWSTWTPHHKQPLVLVGNKCDLVTTAGDAHAAAALLAHKLGAPLVKTSAKTRQGVEEAFALLVHEIQRAQEAVAESSKKTRHQKAVCSCGCSVA
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.  Plays an important role in the tumor-like growth properties of embryonic stem cells.
What are the official names of this protein?
GTPase ERas, E-Ras, Embryonic stem cell-expressed Ras.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: QUEC_AZOC5
Sequence: MSADAGPGSGALVLFSGGQDSTTTLAWALDRFERVETLGFDYGQRHRIELDCRVKVRAAMAALNPAWAAKLGEDHTLALDALGAVSDTALTRDVAIEMTEGGLPNTFVPGRNIVFLTFAAALAYRRGLKHIVGGMCETDFSGYPDCRDDTIKALQVALNLGMDRRFVLETPLMWIDKAETWRLAERLGGRALVDLIVEDTHTCYLGERGPRHPWGHGCGTCPACQLRAEGFARYEAARVSE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MYMT_MYCTU
Sequence: MRVIRMTNYEAGTLLTCSHEGCGCRVRIEVPCHCAGAGDAYRCTCGDELAPVK
What is the function of this protein?
Metallothioneins are small proteins that have a high content of cysteine residues wich allow them to bind heavy metal ions through clusters of thiolate bonds.  MymT binds up to seven ions of Cu(+), with a preference for four to six Cu(+) ions, in a solvent-shielded core.  MymT protects M. tuberculosis from copper toxicity.
What are the official names of this protein?
Metallothionein, MT, Copper-binding metallothionein, Cu(I)-binding metallothionein, Mycobacterial metallothionein.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily.
Protein: ENT1_ARATH
Sequence: MTPISQRISQKSPKLRETKQIQMTTTDKSAGIVTDSEAGPETSLLLNPHEGSTKKAPSDSYHFAYIIYFTLGVGFLLPWNAFITAVDYFSYLYPSTAVDRIFAVIYMLVALVCLFVIVVFYAHKSLASFRINLGLLLFVIALLVVPVLDLVYVKGQVGLYAGFDVTSAAVALSGLGDALMQGGLIGVAGEMPERYMQAVVAGTAGSGVLVSLLRILTKAVYPQDPDGLRKSANLYFAVGIVVMVICAVFYNVAHKLPVIKFHEERKNEELIREKSEEKGSLTGLAWRTTLWDIVTKVKSHGFGIVLLYMVTLSIFPGYITEDVHSELLTDWYPILLIAAYNVFDLVGKCLTAVFMLEDEKIAVGGSIARLLFYPLFWGCLHGPMFLRTEIPVTILTCLLGLTNGYLTSVLMILAPKSVPLRHSETAGIVTVMFLVVGLASGSVIAWFWVI
What is the function of this protein?
Nucleoside transporter involved in adenosine transport and required for nucleotide metabolism which influences growth and pollen germination.  Has high affinity for adenosine when expressed in a heterologous system (yeast).
What are the official names of this protein?
Equilibrative nucleotide transporter 1, AtENT1, Nucleoside transporter ENT1.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.