PharMolix/UniProtQA huggingface dataset:
Protein: GLPB_YERPS
Sequence: MKFDVIIIGGGLAGLACGIRLAEQGKYCAIVSAGQNALHFSSGSLDLLAKLPDGRAVSQPLSALSALAELAPEHPYSKMRNITQLDELVQEAEALLRRCGLDIVGSSAENHLRLTPLGSCRPTWLSLADIPVAPLNGPLPWQRVAVIGIEGFLDFQPQMVASALQDQGIDATADYLHLPALDRLRDNPSEFRAVNIARILDLPENRQPLADELSRLSSTAEMILLPACIGLDKSAPLDALRAVVGKPIQLLPTLPPSLLGMRLHQALRHRFQQLGGLVMPGDAVLRAELVDNRITGLYSRNHGDIPLRAAQMVLASGSFFSNGLVATFDKVYEPILDLDILSLPHRADWSHSNLFAPQPYLQFGVNTDNHLRPLRGGVALENLHAIGAVLGGYDPLQQGCGAGVSLTSAVFVAEQIISEMAVTL
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: DF303_ARATH
Sequence: MKSNKATFFLGLLLVYAFCIMLIESRCYTNDDCKDGQPCPVPLACLFGSCICPWKSQSKLPICQIICANLD
What are the official names of this protein?
Putative defensin-like protein 303.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSPB_HALH5
Sequence: MMNKDQALIFELSKPGRVGHSLPELDVLEQPVETLIPAEFLREEAPELPEVSELQLMRHYTALSKRNHGVDSGFYPLGSCTMKYNPKINEDVARYPGFANIHPYQPEAQVQGALRLMYELQTALAEITGMDEVTLQPAAGAQGEWTGLMLIRAYHEANGDTNRTKVIVPDSAHGTNPASATVAGFESVTVRTDEDGLVDLDHLREVVGEDTAALMLTNPNTLGLFEAHIVEMAAIIHEAGGKLYYDGANSNAILGIARPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPVGVKKELIPYLPKPVVVKDGDSYRLDYDRPHSIGRVKPYYGNFGINVRAYTYIRTMGPEGLRTVSEYAVLNANYMMRRLAPYFDLPYDQHCKHEFVLSGRQQKKLGVRTLDIAKRLLDFGYHPPTIYFPLNVEECLMIEPTETESKETLDEFIEAMIQIAKEAEETPEVVQEAPHHTVIGRLDETTAARKPILRYEKITQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: RS17_NOVAD
Sequence: MPKRILVGTVVSDKTDKTVVVKVERKVKHPLYGKIIRRSKKYHAHDEANAFKTGETVRIEETAPISKLKTWKVIDRVQAGKGTAIEADV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: AAS_PECAS
Sequence: MIHTLLRWVFQRLYRIRIEGDSSQFQQSKLLITPNHVSFLDGVLLALFLPIKPVFAVYSSISDRWFMRWLKPYIDFVPLDPTKPLAIKGLIKVIERGQPVVVFPEGRISVTGSLMKVYSGAAFVAAKSGATIIPVRIDGIELSPFGRLAGVFKRRCLPQVTITYLPPTTLPMPEASSARARRALAGERLHQIMMKARMETRPQHTLYQAFLAARSRYGRHSASIADISFNEDSYQGLLKKSLGVSRILQRFTRADEHVGMLLPNATITAASILGASLRNRIPAMLNYTAGAKGLQSAMKAAGIKTIVTSRQFLEKGKLTDLPKQVSEANWVYLEDLKDTVTLKDKLWILFHLLFPARAMLPQKPDDAAIVLFTSGSEGNPKGVVHSHDSLLANVEQIRTVADFTPGDRFMSALPLFHAFGLTVGLLTPLITGARVFLYPSPLHYRIVPELVYDQNCTVLFGTSTFLGNYARFAHPYDFARLRYVVAGAEKLSETTRQVWQDKFGIRILEGYGVTECAPVVAINVPMATKIHSVGLLLPEMESRLITVPGITRGGRLQLRGPNIMKGYLRVENPGVLETPAAENAEGELQQGWYDTGDIVELDERGFCTIIGRVKRFAKLAGEMVSLESVEQLAVKVSPEAQHAASAKSDSSKGEALVLFTTDSQITRDVLLAQARSSGVPELAVPRDIRYVKALPLLGSGKPDFVTLRQMAEEPNSEQSVIEPSIVKQPITNASEPSA
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YHBQ_SALCH
Sequence: MTPWYLYLIRTADNALYTGITTDVARRYRQHQTGKGAKALRGKGELTLAFAAQVGDRSLALRIEYRIKQLTKRQKERLVTEREAFEALLSSLQTPVLKND
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: ATPUN_HUMAN
Sequence: MNSPEARLCVAQCRDSYPGCQPLKDTRAWASSLKMDPAGLEGGPRDESRDEPPIRAQAASWDQPQGCLTYKGRRSASGTQKQLQLPDTLSSLLCWRGAIMVYIKVTVQTDDSNKLLSLLYR
What are the official names of this protein?
Putative protein ATP11AUN, Putative ATP11A upstream neighbor protein.
Protein: DNLJ_DESAP
Sequence: MKPEEARARAEELRREIEYHDHRYYVLDDPVIEDAEYDRLVRELVALETAYPELVTPDSPTQRVGGRPREGFVTVQHRAPMLSLANAFNAADLADFDRRVRTGLADEDVDYVVELKFDGVAVSLTYEHGRLVRGATRGDGVTGEEITPNLRTIRSIPLRLRQPGAPNVIEVRGEVYMPKEAFARLNERREDAGLPLFANPRNAAAGSLRQLDPGITAERKLDIWLYGIGYTDGIVFGRHSEALAWLGEQGFRVNPHTRIFSTLEEVERHLEHWREARFELPYVIDGLVLKVDRLDQQERLGTTLKSPRWAVAYKYPPEQAETTVEDIIIRVGRTGVLTPTAVLSPVRLAGTTVSRASLHNEDLIREKDIRIGDVVLIHKAGDIIPEILGSRPEKRTGRETPFAMPVQCPECASLLVRPEGEVGVYCSNVACPARLERSLLHFVSRNAFAINGLGPAVIQQLLERRLVADPADLFTLTREELVGLERIGPKSADNLLKAIQNSKRNSLARLIFSLGIRHVGERAARLLAERFGSLAGLMAAGREELEAVPEIGPKIADSVLNFFAREQNRRVVAKLVRAGVNTVADRPAAAGTGPLAGKTFVLTGTLEEFSRAEAAARIEELGGRVVSNVSRRTDYVVLGKNPGGKYDKAVKLGVNIIEEPEFKRLLSGIQSY
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LEU1_BUCDN
Sequence: MSSKVIIFDTTLRDGEQALQASLSVKEKLQIALSLEKCGIDIIEVGFPISSPGDFKSVQTISKKIKNSRICSLARCVEKDIEVAGDAMSSSDFFRIHIFLATSTLHMESKLRKNFDEIIDMAVSSVKKALRYTDDVEFSCEDASRTTMDNLCRIVEKLIKAGVKTINIPDTVGYTIPNELSNIIKNLFERVPNIHKSIISVHCHNDLGMAVGNSISAIQAGARQIEGTINGIGERAGNTALEEIIMAIKVREDILGVSTNIVHKEIYRTSQIISQICNMPIPANKAIVGSNAFAHSSGIHQDGVLKNRKNYEIMEPNTIGVKEVKLNLTSRSGRAAVKYYMDKMGYKDDDYDIDELYSAFLKLADKKGQVFDYDLEALAIFSKKQENAEYFYLKFFSVQSISNGLSTASVKLKCGKKVYTESSTTSNGPVDATYQALNKIINFPITLQKFQLVAKGKGKDALGQVDILVKYENRQFHGIGLATDIIESSAQAMINVLNNIWKSQQVNKKLKNLKKY
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: PEPB_HAEI8
Sequence: MQITLSNNLANDAWGKNAILSFDSNKATIHLKNNEKTDRTLVQQAARKLRGQGIKNVELLGEEWDLEFCWAFYQGFYTAKQDYGIEFPHLDHDLQDELLARIECGDFVRGIINEPAQSLTPVKLAERAAEFILNQADIYNEKSAVSFKIISGEELEQQGYHGIWTVGKGSANLPAMLQLDFNPTQDPNAPVLACLVGKGITFDSGGYSIKPSDGMSTMRTDMGGAALLTGALGFAIARGLNQRVKLYLCCAENLISNNAFKLGDIITYKNGVTAEVLNTDAEGRLVLADGLIEADSQNPDFIIDCATLTGAAKMAVGNDYHSVLSMDDDLVKNLFQSAQEENEPFWRLPFEDFHRSQINSSFADIANIGSVPVGAGASTATAFLSYFIKNYQQNWLHIDCSATYRKSSSDLWAVGATGIGVQTLANLMLSKSLK
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMDB_ECOLI
Sequence: MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQQGDE
What is the function of this protein?
Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate (PubMed:21257746, PubMed:26481419).  Down-regulates ribonuclease 3 (RNase III) activity.  Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation (PubMed:19141481).  Overexpression inhibits biofilm formation via an RNase III-independent pathway.  This inhibition is RpoS-dependent (PubMed:24267348, PubMed:28582517).  Overexpression also results in increased susceptibility to apramycin (PubMed:28034758, PubMed:28582517).
What are the official names of this protein?
O-acetyl-ADP-ribose deacetylase, Regulator of RNase III activity.
What is the protein family that this protein belongs to?
Belongs to the YmdB family.
Protein: PTH1R_RAT
Sequence: MGAARIAPSLALLLCCPVLSSAYALVDADDVFTKEEQIFLLHRAQAQCDKLLKEVLHTAANIMESDKGWTPASTSGKPRKEKASGKFYPESKENKDVPTGSRRRGRPCLPEWDNIVCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTIFGWGLPAVFVAVWVGVRATLANTGCWDLSSGHKKWIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVFMALPYTEVSGTLWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRAGLSLPLSPRLPPATTNGHSQLPGHAKPGAPATETETLPVTMAVPKDDGFLNGSCSGLDEEASGSARPPPLLQEEWETVM
What is the function of this protein?
Receptor for parathyroid hormone and for parathyroid hormone-related peptide.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
Protein: ILVC_RHOP2
Sequence: MRVYYDRDADLNLIKGKKVVIVGYGSQGHAHALNLKDSGVKDVAIALRKGSATAKKAEAAGFKVMEVAEAAKWADVMMMLTPDELQGEIYRDHLHDNMKQGAALLFAHGLNVHFNLIEPRADLDVLMVAPKGPGHTVRSEYQRGGGVPSLIAIHQDPSGNAHDLGLSYASAIGGGRAGIIETSFKEECETDLFGEQVVLCGGLVELIKAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIVTAETKAEMKRVLADIQNGIFTRNWMLENKVNQTSFKATRAKLAAHPIEEVGAKLRDMMPWIKKGALVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ILVC_RHOOB
Sequence: MAVEMFYDDDADLSIIQGRKVAVIGYGSQGHAHSLSLRDSGVDVRIGLKEGSKSRAKAEEQGLTVGTPAEVSEWADVIMVLAPDTAQASIFTNDIEPNLKDGDALFFGHGLNIHFELIKAPEFVTVGMVAPKGPGHLVRRQFVDGKGVPALIAIDQDPKGEGQALALSYAKAIGGARAGVIKTTFKEETETDLFGEQAVLCGGTEELVKTGFEVMVEAGYAPEMAYFEVLHELKLIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDAGTKERMKAILADIQSGEFTRRLVANVENGNTELEGLRKANAEHPIEVTGKKLRDLMSWVDRPITETA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: BIOB_THIDA
Sequence: MNDMTPPVPRRSVSEIEALFALPFADLMYQAQGVHRAHFDPNRIQLSTLLSIKTGGCSEDCGYCPQSVHYDAGVESQGLLDLGDVLKAARAAKDAGASRFCMGAAWRGPKQRELEPVLAMVREVKALGLETCATLGMLKDGQAEQLKEAGLDYYNHNLDTAPEFYGEIITTRDYQDRLDTLERVRRADLHVCCGGIVGMGESRTQRAGLIAQLAALDPQPESVPINLLVRVEGTPLAETEALEPLEFVRTIAVTRLCMPKSFVRLSAGRQQMSDAVQALCFLAGANSIFYGEKLLTTGNPEWERDQRLFDSLGVTAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NUOK_RHILS
Sequence: MVIGLSHYLTVSAILFTLGVFGIFLNRKNVIVILMSIELILLAVNINMVAFSSFLNDIVGQVFALFILTVAAAEAAIGLAILVVFYRNRGSIAVEDVNMMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2548_STAAW
Sequence: MKKLAVILTLVGGLYFAFKKYQERVNQAPNIEY
What are the official names of this protein?
Uncharacterized protein MW2548.
Protein: ADD_CLOBL
Sequence: MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIGKGVVAIDLCAGEEPHFPGKYIEVLKLAKECGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKDCAEAYKLVKEKNIPLEVCPTSNLHTKAFESYETHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIGDYKILYLNAVEASFASSETKKMLKSYVKEITG
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: MODB_MYCBO
Sequence: MHPPTDLPRWVYLPAIAGIVFVAMPLVAIAIRVDWPRFWALITTPSSQTALLLSVKTAAASTVLCVLLGVPMALVLARSRGRLVRSLRPLILLPLVLPPVVGGIALLYAFGRLGLIGRYLEAAGISIAFSTAAVVLAQTFVSLPYLVISLEGAARTAGADYEVVAATLGARPGTVWWRVTLPLLLPGVVSGSVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDPDAAVALSLLLVVVAALVVLGVGARTPIGTDTR
What is the function of this protein?
Part of the binding-protein-dependent transport system ModABCD for molybdenum; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Molybdenum transport system permease protein ModB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CKB11_ORYSJ
Sequence: MEKYEKLEKVGEGTYGKVYKAQDRATGQLVALKKTRLEMDEEGIPPTALREISILRLLSQSLYVVRLLSVEQATKNGKPVLYLVFEFLDTDLKKFVDAYRKGPNPRPLPTNVIKSFLYQLCKGVAHCHGHGVLHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPMKSYTHEIVTLWYRAPEVLLGSTHYSTGVDIWSVGCIFAEMVRRQALFPGDSELQQLLHIFRLLGTPTEEQWPGVTDLRDWHEFPQWKPQILERQVPSLEPEGVDLLSKMLQYNPANRISAKAAMEHPYFDSLDKSQF
What are the official names of this protein?
Cyclin-dependent kinase B1-1, CDKB1;1, CDKB;1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: DEF_RHOOB
Sequence: MAILPIRIVGDPVLHEPTETVSESPAELSELIADMYDTMDAANGVGLAANQVGIPLRLFVYDCPDVDETGKPFRRRGCVVNPVLETSERPETMPDPDDDVEGCLSVPGEQFPTGRAEWAKVTGTDADGNAVEIEGRDFFARMLQHEVGHLDGFLYVDMLVGRNARAAKKTIKRAGWGVPGLSWVPGTVEDPFGHDD
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RAPA_SHEHH
Sequence: MPFSLGQRWISDTESELGLGTVVGVEGRMVTVLFPATGENRLFSRTEAPLTRVIYNPGDTIESHEEWSLVVTEVEEKDSLIIYHGTHSETGEQVSLRETLLNHNIRFNKPQDRLFAGQIDRLDRFNVRYQCQLLRNKLATSDLLGLQGPRVGLIPHQQWIAHEVGQRFAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERILVIVPDTLRHQWLVEMLRRFNLRFSVFDEDRCVEAYADNDNPFYTEQLVICSLDLLRKKRRLDQALDADWDLMVVDEAHHLEWSEEAPSRAYQIVEALSEEIPGVLLLTATPDQLGHQSHFARLRLLDPDRFYDYQAFLKEEDSYKDVATAADALASGESLSDESIAGLTQLLSEKDISASIALIQDDSADTDTRLQARDELLQDLLDRHGTGRVLYRNSRASVKGFPQRNLHVHPQKMPEQYVTAYRVSAMMNKHLDTNAKVRQVLSPEKIYQDFDSGSASWWKFDPRVDWLIDFLKTNRSKKVLIIASQAETALSLEEALRTREGIQATVFHEGMSIIERDKAGAYFAQETGGAQALICSEIGSEGRNFQFASNLVLFDLPLNPDLLEQRIGRLDRIGQKNDVEIHLPYLANTAQERLTEWYHQGLNAFECTCPSGHILFNEFSGELLETLLNNDETSLETLLDNTKARYQELKLAMEQGRDKLLEINSHGGERANKLVQSLADKDGDTQLIGSVIRLWDIIGVEQEDSGENAIVLHPSEHMMFPTYPGLPEDGITVTFDREMALSRDDIALITQEHPLVQTGLDLITSSETGTTSVAVLKNKALPAGTIFLELIYLADASAPKSSQLYRYLPPTPVRVLLDKNGNNLSDNVTYESFNKQLSAVNRHIASKLVNASQAILHPLFAKAETFANAELQTLTACAREKMTSQLSGELERLKALKAVNPNIRDEELSHLSEQMSELNRYLDSSKLQLDAVRLVLVSHA
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: DLGD_ECOL5
Sequence: MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSLVLDMIATLLSDGASVAEVTEDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABPA_ECOLI
Sequence: MESNDSGGVAAKHGFLFQDCVAAYHVTRMLRDKTIRSVRCEVTDDIDIVSDGYIDFVQVKSTGKTRWNISDIVQNSKGADKKTIPCSSILHKSMQCESDLSLGRRYSIVTEEKVNKTLEYLTISPNARLDKPGRQELIDDLNKRTDNFLTDSGISVSDWIDAATWEVFSSLRELELLGIKNIRLASQDLHGVILSSETVAEDIWCRILDTVTRKGEHSRRIHSADDKSYLRPDLLEWFKQRVEDDQSRSGRKIYVKRDLPHILTPFRAPMASVCAKRKGQVLHQQYSLKKYRYKHIADNVCQWLDEVFLRPKEMSDIHKLTFIEKRERLKNSVFKSLHDVSEFLGRVLLHATIRQHHESQPIPCMLYVEKAGAEKILENVHIVRRDPEGDQLWIGFSELVTDINIAVRLPEIRDQLYEDISDCIDTARKKILDIKDDNYLLRHDIDEILDGSQPFDAHLDRFTFVLFVGYDSNLLTEPETPGFEDDLEKETAVLFEKFAADLIEDSPFANLCIHVFIYPAPSLERLTQLVDEKVREVV
What is the function of this protein?
Part of an antiviral system composed of AbpA and AbpB; when both are expressed from a plasmid they confer resistance to phages T2, T4, T7 and lambda but not RB32 or RB69.  Resistance is temperature dependent, it can be seen at 30 degrees Celsius but not at 37 or 42 degrees Celsius.  The system impairs phage but not bacterial DNA synthesis (shown for T4, T7 and lambda).  Partially suppressed by mutations in T4 gene 41, a replicative helicase.
What are the official names of this protein?
Anti-bacteriophage protein A.
Protein: PYRF_CLOK5
Sequence: MIIDELYETVNKKGNVCVGLDTALSYIPESMRESHENVEDCIFEFNRTIIDSTLDAAACYKVQIAYYEALGIEGLRAYSKTLKYIKDKKALSIADIKRGDIAKTAEMYAKAHFEGEFESDFVTLNPYMGFDTIEPYLPYVKNNNKGLFILIRTSNKGAKDLQYISTRKNTKLYNIVGKKVSSLGEKYMGNCGYSSLGGVMGCTHQEEGIKLRKKLKNIFFLIPGYGAQGGTAEDISAYLKRGNGGVVNSSRGILLAYKKEEDGFKKYGECARQECVKIRDDILKISQNKNS
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: NAGG_RALSP
Sequence: MSEPQRLKPVFPQDPKWPGEGSSRVPFWAYTREDLYKRELERLFYANHWCYVGLEAEIPNPGDFKRTVIGERSVIMVRDPDGGINVVENVCAHRGMRFCRERHGNAKDFFCPYHQWNYSLKGDLQGVPFRRGVKQDGKVNGGMPKDFKLEEHGLTKLKVAARGGAVFASFDHDVEPFEEFLGPTILHYFDRVFNGRKLKILGYRRQRIPGNWKLMQENIKDPYHPGLLHTWFSTFGLWRADNKSELKMDAKFRHAAMISTRGQGGKNEEVVSGVDSFKEQMKVNDPRLLDIVPEPWWGGPTAVMTTIFPSVIIQQQVNSVSTRHIQPNGHGSFDFVWTHFGFEDDNEEWTQRRLIQANLFGPAGFVSADDGEVIEWSQEGFEQKPTHRTVIEMGGHEIGDTDHMVTETLIRGMYDYWRKVMGE
What is the function of this protein?
Oxygenase component of the salicylate 5-hydroxylase (S5H) multicomponent enzyme system which catalyzes the 5-hydroxylation of salicylate to gentisate.  Active only on substrates with a ring-substituted carboxylate group with an adjacent hydroxyl group.  Primarily active against salicylate and substituted salicylates, but not against 2-hydroxycinnamate, 3-hydroxycinnamate, 2-hydroxyphenylacetate, 3-hydroxyphenylacetate, 2-hydroxybenzophenone, 1-hydroxy-2-naphthoate, 4-methoxysalicylate or 2-hydroxyacetophenone.
What are the official names of this protein?
Salicylate 5-hydroxylase, large oxygenase component, S5H large oxygenase component, Salicylate 5-hydroxylase, oxygenase component NagG, Salicylate 5-monooxygenase, hydroxylase large subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: SPB4_BOTFB
Sequence: MAIEGEKKKDPRAWDALTPSLAEWVLDAISSMGFEKMTPVQASTIPLFMGNKDVVVEAVTGSGKTLSFLIPVVEKLLRLEEPLKKHHVGAIIVSPTRELATQIHSVLTSLLKFHEPSAEALQPLEEGEKRKPSSTLRVIPQLLLGGTTTPAQDLSRFLKNSPNLLISTPGRLLELLSSPHVHCPQSSFEVLVLDEADRLLDLGFKDDLQKILGRLPKQRRTGLFSASVSEAVGEIVRVGLRNPVKIAVKVKGAGGGDKMTPASLQMSYLLTPPTHKFPALLSLLSQLEPTPQKSIIYLSTCAAVDYFQPLLEAVLPKQFGLVSLHGKHPPNVRQRNFSKYVAAVSPTILLTTDVAARGLDIPQVDLVVQIDPPSDPKVFLHRCGRAGRAGRKGLSVIFLQPGREEDYIPFLEIRKTPITPLKRPEISTTGEAAKILISKMRKEVLSDRALYDKGQRAFVSWVQAYSKHQASSIFRVADLDWTDLGNAWALVRLPKMPELKKWEGDKTLGIKLDMSEYAYKDKIREKARRVAMEEAKNAGPYVPTEEQIAKKKQREAWSQKHEKQDLKELKREKKKRKREIERLEKMTDEEKKEEQAKEKELQDLIEQVKKRKIEDDADVEFEGFAD
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase spb4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.