PharMolix/UniProtQA huggingface dataset:
Protein: IF3_NEIMB
Sequence: MIAQEREARINGEITAKEVRLISESGEQLGVVSVREALAMAEGQDVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGTDEGDYQIKMRNINRFLADGDKVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFPKMEGRQMVMMIAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOKE_BACSU
Sequence: MGQKFHKLNSKYGIIDYPILLKDLESIIQEFPKSERKFYEYAIKALKKEVGKKEKILHMTSADPKLTKFGFMVITEKKLLFVTMKGGFFGGADTEVVEFKSIKEVDFDIAPNPLGMATMQLGILHLKIKGKLGMSSKRTIRNIDEHSLDKIVAILREQTK
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YokE.
Protein: AMYG_SCHOC
Sequence: MIFLKLIKSIVIGLGLVSAIQAAPASSIGSSASASSSSESSQATIPNDVTLGVKQIPNIFNDSAVDANAAAKGYDLVNVTNTPRGLTGILKLKEATNIYGYDFDYLNLTVEYQADTRLNVHIEPTDLSDVFVLPEHLVVKPLVEGDAQSYNFDNSDLVFEYSNTDFSFEVIRSSTKEVLFSTKGNPLVFSNQFIQFNSSLPKNHVITGLGESIHGLVNEPGSVKTLFANDVGDPIDGNIYGVHPVYLDQRYDTETTHAVYWRTSAIQEVLIGEESITWRALSGVIDLYFFSGPTPKDAIQQYVKEIGLPAFQPYWSLGYHQCRWGYDTIEKLSEVVENFKKFNIPLETIWSDIDYMDSYKDFTYDPHRFPLDEYRKFLDELHKNNQHYVPILDAAIYVPNPNNATDNEYQPFHYGNETDVFLKNPDGSLYIGAVWQVTLFSRFLSRKHSDMDKVIKDWYELTPFDGIWADMNEVSSFCVGSCGTGKYFENPAYPPFTVGSKATSYPVGFDVSNASEWKSIQSSISATAKTSSTSSVSSSSSTIDYMNTLAPGKGNINYPPYAIYNMQGDSDLATHAVSPNATHADGTVEYDIHNLYGYLQENATYHALLEVFPNKRPFMISRSTFPRAGKWTGHWGGDNTADWAYAYFSIPQAFSMGIAGLPFFGADVCGFNGNSDSELCSRWMQLGSFFPFYRNHNYLGAIDQEPYVWESVAEATRTSMAIRYLLLPYYYTLLHESHTTGLPILRAFSWQFPNDRSLSGVDNQFFVGDGLVVTPVLEPGVDKVKGVFPGAGKEEVYYDWYTQREVHFKDGKNETLDAPLGHIPLHIRGGNVLPTQEPGYTVAESRQNPFGLIVALDNDGKAQGSLYLDDGESLVVDSSLLVSFSVSDNTLSASPSGDYKADQPLANVTILGVGHKPKSVKFENANVDFTYKKSTVFVTGLDKYTKDGAFSKDFTITW
What is the function of this protein?
This glucoamylase has a specificity toward both alpha-1,4 and alpha-1,6 linkages.
What are the official names of this protein?
Glucoamylase 1, 1,4-alpha-D-glucan glucohydrolase, Glucan 1,4-alpha-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
Protein: ODO1_RICPR
Sequence: MEEYFNKTGYLFSGNAVFVEELYRQYLANPNSVDQTWQEFFADIKDNNVVLNKSTAKVISTNVTNKELLNNNLSSETLNNLKAKEMISAYRRNAHYLANLDPLGLEIRKTKNDLKLNIEAFGLDSSQLGENINIMDEFIGTWNCKLSELVTKLDKVYTSSIGVEFDQIENVEEKNWLYTKLETDITFTSEEKKSILNDLVEVECFEQFLHIKFPGAKRFSIEGGDASIVAMNKAIDLSMHQGVEEIVIGMAHRGRLNTLTKVVGKPYKEVIASFINGNIFPDGLNVSGDVKYHLGYSADRVRANQKIHLSLADNPSHLEAINSIVAGKVRAKQDIFVDTKRSKIKAILVHGDAAFCGQGVVAESLSMSPLTAYNVGGILHFVINNQLGFTANAADTRASRYSTEFAKIISAPILHVNGDDIEAVLKATDIAVEYRQKFSKDVVVEIICYRKYGHNEGDEPMYTQSKMYNIIKSKPTPGSIYANELVKNGIIDNNYYAKLKEKFKIRLDQEYEQAKSYKQETHFFEGYWKGISRIRGKDAITGVNKKILQDLGTKLCEIPKDFAINPKLIRLFEVRKTTLTTDQPIDWATAEQLAFAHLLCSGINIRLTGQDSARGTFSHRHSILHNQIDDTTYIPLNNLSKTQAKYEVANSNLSEYAALGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSATKWLRMSGLVVLLPHAFEGQGPEHSSARLERFLQLAAEENMYITYPTTPASIFHLLRRQILESTRKPLIVMSPKSLLRHKYAVSKLDELGENTTFIPILDEVTKIDTNNVTKVILCSGKVYYDLFAMRTNNSNIVIIRLEQLYPFEKKLVASLLKKYNKAQAFIWCQEEPKNMGAWHYIATHLNDALKEAEINNEFKYVGREESASPAVGSLQVHNKQQEKLLMEALGDDIIKEKLY
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: SPRE2_RAT
Sequence: MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREPNTRTISSPTSCEHRRIYTLDPYPMDLYHPDQRLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDSTEDADSYVRFAKGEVPKHEYTYPYVDSSDFGFGEDPKGNVIKTQPPRAKSRRRKENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHHCGVMCRCCGGKHKAAA
What is the function of this protein?
Negatively regulates Ras signaling pathways and downstream activation of MAP kinases.  Recruits and translocates NF1 to the cell membrane, thereby enabling NF1-dependent hydrolysis of active GTP-bound Ras to inactive GDP-bound Ras (By similarity).  Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity).
What are the official names of this protein?
Sprouty-related, EVH1 domain-containing protein 2, Spred-2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Detected in the cytoplasm of the stratum spinosum cells, where it is associated with cytoplasmic vesicles that are supposed to be secretory granules.
Protein: 3SBA_HEMHA
Sequence: LKCKNKLVPFLSKTCPEGKNLCYKMTLKKVTPKIKRG
What is the function of this protein?
Hemextin AB complex: specifically inhibits the activation of FX (F10) by the TF-FVIIa complex (extrinsic tenase complex (ETC)) (IC(50)= 100 nM, Ki=25 nM) by non-competitively inhibiting the enzymatic activity of FVIIa.
What are the official names of this protein?
Hemextin A, Hemachatus extrinsic tenase inhibitor A.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IB cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEA_PHEZH
Sequence: MKLADFDFDLPEEAIALRPANPRDAARLLLVEPGQDFRDLAVRDLPGLLRAGDVLVLNDTRVIPARLKGVRTREGSRVAVEATLHQRKAGHVWTAFMRPGKRLAPGDRVSFGETDDRACFLGALDATVKEKGEGGEVTLAFDLSGPDLDAAIAERGAMPLPPYIAAKRAEDEQDRADYQTVYAEEDGSVAAPTAGLHFTPELLARLAQAGVTTERVTLHVGAGTFLPVKTEDISEHRMHAEWGEVDAATADRLNAARAAGGRIVCVGTTSLRLLESAAGEDGVVRPFRDETAIFITPGYRFRAADGLMTNFHLPKSTLFMLVCAFAGTDTMRAAYRHAIETGYRFYSYGDSSLLWRA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM41_MOUSE
Sequence: MALQALHSSGVGLRRILAHFPEDLSLAFAYGSAVYRQAGPSAHQENPMLDLVFTVDDPVAWHAMNLKKNWSHYSFLKLLGPRIISSIQNNYGAGVYFNPLIRCDGKLIKYGVISTGTLIEDLLNWNNLYIAGRLQKPVKIVSMNENMALRAALDKNLRSAVTTACLMLPESFSEEDLFIEIAGLSYSGDFRMVIGEEKSKVLNIVKPNVGHFRELYESILQKDPQVVYKMHQGQLEIDKSPEGQFTQLMTLPRTLQQQINHIMDPPGRNRDVEETLLQVAQDPDCGDVVRLAISSIVRPSSIRQSTKGLFTAGMKKSVIYSSRKLNKMWKGWMSKAS
What is the function of this protein?
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
What are the official names of this protein?
Phosphatidate cytidylyltransferase, mitochondrial, CDP-diacylglycerol synthase, CDP-DAG synthase, Mitochondrial translocator assembly and maintenance protein 41 homolog, TAM41.
What is the protein family that this protein belongs to?
Belongs to the TAM41 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: FTSH_BARBK
Sequence: MNSNFRSLMIWGLIALFLIVLFSFFNGNRQRASNGEVSYSEFLQKIDNNELKTVTIQGQKLTGQTADRRMISTYAPRDPGLVQRLNTNKVNIRAVPESSGNSIFLNLLFSLLPVLIIVGAWIFFMRQMQGGSRGALGFGKSKAKLLTEAQGRVTFKDVAGVEEAKQDLQEIVDFLREPQKFQRLGGRIPRGVLLVGPPGTGKTLLARSIAGEANVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRHRGAGLGGGNDEREQTLNQLLVEMDGFEPNESIILIAATNRPDVLDPALLRPGRFDRQVVVPNPDVAGREKILEVHVRNVPLAPNVNLRVLARGTPGFSGADLMNLVNEAALMAASRNKKVVTMQEFEDAKDKVMMGAERRSTAMTQEEKELTAYHEAGHAIVALNVPVSDPVHKATIVPRGRALGMVMQLPEGDRYSMSYLWMVSRLAIMMGGRVAEELKFGKENITSGAASDIEQATKLARAMITRWGFSDMLGHVAYGDNQDEIFLGHSVARTQNISEETARMIDAEVRRLIDDAYKTATKILKTQNKQWLALAQGLLEYETLTGTEINEVIAGKPPSRTQGSDTAPLRTSSVPKIGAKNSKGASKSGDAEETEPSVGTKATAASSAKKVVKNASAKSAEKKASGTQVKAATPAATSIKATSAKVASAKAETENVASAQAATENVAMVKAATANVAKKSVESAQADDAEKKRLEEHNKSAHNKKGNLTAGAASNTEDEK
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: RISB_ALIB4
Sequence: MKVIEGVLRLKGNEKIAVINGRFNHIITDRLVEGARDAFKRHGGNEDNLDLILVPGAFEIPFALEKALSSGKYDAVCCVGAVIRGATPHFDYISAEATKGIATVGLKYGKPVSNGVLTTDTIEQAIERAGSKVGNKGAEAMVTIIEMLDLYNEMGK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SYE_SYNE7
Sequence: MSVRVRIAPSPTGNLHIGTARTAVFNWLFARRHQGQFILRIEDTDLERSRSEYTDNILTGLQWLGLNWDEGPFYQTQRLDLYKAAVQQLLDSGKAYRCYCTEAELEALRESQRARNEAPRYDNRHRDLTPEQEAAFQAEGREAVIRFRIDDDREIAWTDLVRDRVVWKGSDLGGDMVIARRSPAGTIGQPLYNLAVVVDDIDMTISHVIRGEDHIANTAKQILLYEALGAAVPEFAHTPLILNKEGRKLSKRDGVTSISDFQNLGYLPEAIANYMTLLGWSPVEGMDERFSLAEAATVFDFDRVNKAGAKFDWDKLNWLNSQVIKEKSASELVALLQPFWSKAGVDTAAYPAAWLEELATLLGPSLVTLTDIVGQSQLFFSQGIELQEDAIAQLGQAGSKAVLQQILEALPSEALTLEVAKGLIDQAVKAAGVKKGIGMRSLRAALMGSMQGPDLLTSWVLLHQAGQAQPRLQAAIAAAQG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_ACIAD
Sequence: MSQTLQAAYAAKRKARRFAVQGIYEWQMSRNPVHEIEARTRVENAMHKVDLGYYHELLTQVVAQHETLDTLLVPVLDRELNALDGVELATLRLGAYELRDHLEIPYRVVLDEAIELAKHFGGADSHKYINGVLDRLASRLREAEKQQAN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MGR2_YEAST
Sequence: MPPLPQNYAQQQPSNWDKFKMGLMMGTTVGVCTGILFGGFAIATQGPGPDGVVRTLGKYIAGSAGTFGLFMSIGSIIRSDSESSPMSHPNLNLQQQARLEMWKLRAKYGIRKD
What is the function of this protein?
Required for cell viability in cells lacking mitochondrial DNA.
What are the official names of this protein?
Protein MGR2, Mitochondrial genome-required protein 2.
What is the protein family that this protein belongs to?
Belongs to the MGR2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MNTP_BACCZ
Sequence: MTFEQLIPLIIMAFALGMDAFSVSLGMGMMALKIRQILYIGVTIGIFHIIMPFIGMVLGRFLSEQYGDIAHFAGAILLIGLGFYIVYSSILENEETRTAPIGISLFVFAFGVSIDSFSVGLSLGIYGAQTVITILLFGFISMLLAWTGLFIGRHAKGMLGTYGEIVGGIILVGFGLYLLFPI
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS12_LEVBA
Sequence: MPTINQLVRKGRKSKSSKSDAPALNYGYNSFKKAQVKNPAPQKRGVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGALDTAGVTDRRQGRSKYGTKKPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RER1_CHICK
Sequence: MSEGDSIGESVHGKPSVVYRFFTRLGQIYQSWLDKSTPYTAVRWIVTLGLSFIYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTRQNEEFRPFIRRLPEFKFWHSATKGILVAMACTFFEAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRKYKGKEDVGKTFAS
What is the function of this protein?
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
What are the official names of this protein?
Protein RER1.
What is the protein family that this protein belongs to?
Belongs to the RER1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RS3_RAT
Sequence: MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPSGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA
What is the function of this protein?
Component of the small ribosomal subunit (By similarity).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity).  Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413).  Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity).  Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity).  Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity).  Stimulates the N-glycosylase activity of the base excision protein OGG1 (By similarity).  Enhances the uracil excision activity of UNG1 (By similarity).  Also stimulates the cleavage of the phosphodiester backbone by APEX1 (By similarity).  When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage.  Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (By similarity).  Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (By similarity).  Represses its own translation by binding to its cognate mRNA (By similarity).  Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (By similarity).  Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization (By similarity).  Involved in induction of apoptosis through its role in activation of CASP8 (By similarity).  Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (By similarity).  Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (By similarity).
What are the official names of this protein?
40S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleolus. Mitochondrion inner membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, spindle. Note=In normal cells, located mainly in the cytoplasm with small amounts in the nucleus but translocates to the nucleus in cells undergoing apoptosis. Nuclear translocation is induced by DNA damaging agents such as hydrogen peroxide. Accumulates in the mitochondrion in response to increased ROS levels. Localizes to the spindle during mitosis. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: 6PGL_NEIMA
Sequence: MFVWHEYENAAEAAQSLADAVADALQGALDEKGGAVLAVSGGRSPIAFFNALSQKDLDWKNVGITLADERIVPTVHADSNTGLVREYLLKNKAEAAMWIPMVEDGKTETELHPDAVVDYALKHYKQPDVLVLGMGNDGHTASIFPKAPQFQTAIDGSAGVALVHTTPVTAPHERVSMTLDAIAHTGHVFLAIRGEEKKAVFDQAAQGENREYPINLVLNHQGVNCHVFYAE
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: AML5_ARATH
Sequence: MDIPHEAEAGAWGILPGFGRHHHPSSDATLFSSSLPVFPRGKLQLSDNRDGFSLIDDTAVSRTNKFNESADDFESHSIGNLLPDEEDLLTGMMDDLDLGELPDADDYDLFGSGGGMELDADFRDNLSMSGPPRLSLSSLGGNAIPQFNIPNGAGTVAGEHPYGEHPSRTLFVRNINSNVEDSELTALFEQYGDIRTLYTTCKHRGFVMISYYDIRSARMAMRSLQNKPLRRRKLDIHFSIPKDNPSEKDMNQGTLVVFNLDPSISNDDLHGIFGAHGEIKEIRETPHKRHHKFVEFYDVRGAEAALKALNRCEIAGKRIKVEPSRPGGARRSLMLQLNQDLENDDLHYLPMIGSPMANSPPMQGNWPLNSPVEGSPLQSVLSRSPVFGLSPTRNGHLSGLASALNSQGPSSKLAPIGRGQIGSNGFQQSSHLFQEPKMDNKYTGNLSPSGPLISNGGGIETLSGSEFLWGSPNARSEPSSSSVWSTSSTGNPLFSTRVDRSVPFPHQHQNQSRSHHHFHVGSAPSGVPLEKHFGFVPESSKDALFMNTVGLQGMSGMGLNGGSFSSKMANNGIINSGSMAENGFSSYRMMSSPRFSPMFLSSGLNPGRFASGFDSLYENGRPRRVENNSNQVESRKQFQLDLEKILNGEDSRTTLMIKNIPNKYTSKMLLAAIDEKNQGTYNFLYLPIDFKNKCNVGYAFINMLNPELIIPFYEAFNGKKWEKFNSEKVASLAYARIQGKSALIAHFQNSSLMNEDMRCRPIIFDTPNNPESVEQVVDEESKNMDLLDSQLSDDDGRERS
What is the function of this protein?
Probable RNA-binding protein that plays a role in meiosis and vegetative growth.
What are the official names of this protein?
Protein MEI2-like 5, AML5, MEI2-like protein 5.
Protein: PGK_ANASK
Sequence: MALRTIDALDLAGKRVFIRVDFNVPLDPQGRVTDDARIRAALPTIRHAIQAKAKVILASHLGRPKGKPDDRQKLTLEPAAVRLSELLSQDVILADDCVGDGVKKLVRDLKDGHVLLLENLRFHPEEEKNDEAFARELASLADVWVNDAFGTAHRAHASTAGMARFVKEKAAGFLVQKEVEYLGKALGSPARPFVAIVGGAKVSDKIKVLENLIAKADAICVGGAMAYTFLKAQGVPVGKSLVEEDKLELARQILERAEARKVDLLLPVDHVCGAEPKETAERVVVNDRAIPDGLMGLDIGPKTLDRYRQRIAAAKTVFWNGPMGLFEQKPWSEGTFGVAKAMAASPAVTVVGGGDSAAAVEQAGIVDAMKHVSTGGGASLEFIEGRELPGVKACEE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C_CHLAT
Sequence: MEFIYRYAWLIPILPFLGSMIIGLGLISLRRATQTLRWRFAFFNIVLLGIALIFSISILISQLNGHPPYKWLIEWIVTNQFSLEIGYSIDPLTSVMLVLVTSVAILVMIYSDSYMSYDQGYVRFFAYLSLFTASMLGLVLSPNLVQIYVFWELVGMCSYLLIGFWFTRPAAADACQKAFVTNRVGDFGLFLGILGLYWVTGSFEFQTISNRLSNVLLGDFVLPGSHPVQVELLVLFNLLVFLGPMAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMFPIFNQFPIVMGFIAWIGAITAIIAAIIAVTQNDLKKGLAYSTISQLGYMIMAMGVGSYTAGLFHLITHAYSKALLFLGSGSVIHGMEPVVGFNPSKNQNMLFMGKMREFMPVTAITFLLGTLSLCGIPPMACFWSKDEILSQTFQAQPILWIIAWVTAGLTSFYMFRMYFLVFEGKQFRGGEFIYDVRAKSLPKESNKKILIPLIILALVTTLVGFVGTPFNNMFAKFINLTRLEEHPFEWNEFLSMSGSSVGIALIGLTLASLIYKESKIDANQIANTLTPLYKLSFNKFYIDHIYQIGFIKVNRSLAQKALELDQQIIDGFINFTGFFTIMTGEILKYVENGRVQSYVFVIIFATLIFVLASQGF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CNOT4_MOUSE
Sequence: MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPYPEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTPSPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQTPSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIEKELSVQDQPSLSPTSLQNASSHTTTAKGPGSGFLHSAAPTNANSLNSTFSVLPQRFPQFQQHRAVYNSFGFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIPIAGEEEVKVSTMPLSASSHSLQQGQQPTSLHTTVA
What is the function of this protein?
Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins.  Involved in activation of the JAK/STAT pathway.  Catalyzes ubiquitination of methylated RBM15.  Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA.  As part of the PINK1-regulated signaling, upon mitochondria damage, ubiquitinates ABCE1 and thereby recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy.
What are the official names of this protein?
CCR4-NOT transcription complex subunit 4, CCR4-associated factor 4, E3 ubiquitin-protein ligase CNOT4, Potential transcriptional repressor NOT4Hp, RING-type E3 ubiquitin transferase CNOT4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IF2A_SULIK
Sequence: MIYSRSRLPSEGEILIATVKQVFDYGSYVTLDEYGGLQAFLPWSEVSSKWVKNIRDVLKENRKVVVKVIRVDRRKGTVDVSLKKVTDDERRKKNLQWKKIQRLDKILELVSQQLKLSEKDAWEQVAWKLEAKYGDPISAIERAVKEGEKILIDAGVPEIWIKPLLEEAAKHTEEKKVKMSGLITVKTSEPLGVQKIKEVISKALENIEQDYESILNVKIYTIGAPRYRVDVVGTNPKDASEALNQIISNLIKIGKEENVDISVVKK
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit alpha, aIF2-alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: PROB_PELUB
Sequence: MYLKDSKIIVIKIGSSLLIDDKKKVRRKWLTEFAKDIQELIKQNKKVIIVSSGAIAMGCKKLNISKKNLKIDKSQAVASIGQIELMNLFSETFVKLKINISQILLTLEDTEQRRRALNAKRTFDNLFKLGFVPIVNENDTIATSEIKYGDNDRLASRVAQISGADSLILLSDVDGLYTHNPKIYKNAKLIKEIRNIDKDIEKIATKSISEHGTGGMKTKIDAAKICQLSGCQMVIANGLVNRPIKKITEENKCTWFLPKVSKLDARKKWIISSVSPKGALIIDDGAKQALSNGKSLLAAGIKKVSGRFSKGDHIKVLDKNNYECARGLSSFSSNEIEKIMGHHSKEIEKLLGYISKSEVIHKDDIVEV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.