PharMolix/UniProtQA huggingface dataset:
Protein: SMG1_CAEBR
Sequence: MLTSKNNDIGNLIEIFRQRDITYKERKATLQKIEELIPKVPDLEALNTKWIYLLDNAVWPLIVKSDRMDLKSLAGKVTRHVGALLFDSPFYPEFLLWLGTLLQNTPKKNDDARADIVFSVYYIVGAISQKSENRLGKNDEEYVRKSLEWLIRVIPNSSSAVYNNCLKGIILISNTFRKVTDDLYESCLRAIVSNFPDFNSHEKNFERLLDTVNLFSDHFSKDPVLAEEMVRIIRPDIKKNGLRNTRELKKRLKLTMAIVKMAKSQQILVETNEMMCELQAELEGNGGKWSSAALITIICDLLNELLILGKNDAEMRQSVEESLGNLLKDLNLSKQNTKEKQAFFNSLAKIVKQLPAESDVKTRIHHIVFNSDTGLFNIQNDDNRIFGHNTIYRDLVNLISVLLTPTSLSHLQATYTDLRKIMMESMSKLKQSERWHESILLLFFSALQGISCAKSSLIVMIGIRPSIFELFCDELPLTEYWLASNHPEVYHIFITILVGHLKAHDFYVSQSDYLVHGETPTGHAYGQTKREYVRKQVIALHKIIGGFGNRLWKKTRFLISTWLHSLVVIARDQKISAESFRLKEWVRLRNTVIQHSVLDWNNESINQALTVLSTVTNWSALPLELNKDITDKTKKATWKEATTIWESGDFKTYIRQSLSTTYQMSQERQQKQIGSTSFGAEEFNLVTNFLLKQIVPTTFKKGPYVWMDEVLETAIQGCKNISQEKSDVPETFMEKWDWIINQTANFCIVNKMKTPLGKPMQTFAAFENEIKRLAKEVINRKSSDKKPKSTTEDVPPPATPPLKFSIQWLRVHLLLKLIEVLEKIMISSIRGGSSIFNLTEIPVTARQFFIMNSSSCEVWLNRVYYPALIVAYFNGYYGLVIRFGSNALNHYARQKGSDEKMITNGVCTACLMSLSMAVLGEPMEIVGLRRRVREEFGTEMGQKLMEALGEMASARYEIALVQLEAILVVDSSINETLRIIIQIAITDMLNRIRLPDAVRYYKKTLFGEDEEAQVAEDFRSIEMLTKFEKLNYGVAEKRQVVDWSARERLQLVESAYSQTMKRNELLELQKEMSAMGALALSADSSCKLYSDISSTSLVIANLVDRMTGTSHWKNQLTDVEMFDRAEEGNEGDKLTICRKLMHWGRHMKHHRGQSFAAHGEIIRFSRKTSNCELAFFHINSAIRGEKLEAWQRLEVERQRLKLVKSQHFDVRVREMNEVFGSLADVFSTSIEMKQKFQNLDDQTKDLMVANGYLSDIAKREEHMSRASIQLADFFDTLPTIDTVLTPNLYNTIIWSEIQSRSNSLSCGYAGLVGALYNLSADLCPSLAKAHLKMAKWTYEMAKIENFPNISPFALYQFGQTAQENEELWRSLDATSLVNLEKQVRKIVPDAMRASVLLSPNNPYLLLWEAASAHRRKFLCITVSSYFQFIHNMSGDFECLPYSKREETTLATLRILEMLVKHGEVLVDVINDGLSRTNVHVWKEILPQLFARLSHPSDHIRKTLVDLISRVCTAAPHAVVFQVVSGAASSTEVSDLEEQQNDDRNRVRACCEQLETKMAQSYPNLVRDVRQFVAELERINLLNEEKWSVVLGTMEHEMEKRLALIKAENAKTDFSMHLMPKQKDEIISKKTKLLTRQIFDVLDELYEKTIVAQPETENEKEFFNTFSEMLTKAHTESKNNRYNSPEASWAPFKNLVSNFAHRTNKKGMQTFQTADISQYLATLGKSCVPMPGQESVEFDRVVSIARVADNVTILPTKTRPKKLGFIGSDGKQLAFLFKGREDLHLDERVMQFLRLCNVMLQSEKGKSRQIAEYQAHHYAVIPLGPRSGLIKWVEGATPIFHIYRKWQMKEKALKQATKKNGETVPEIEKPTNMYHNMIRQAFTAHNIDAIIASDRSKWPAQILEEVFDGLCSKTPTDLISREIWMRANDSTAWWAVTKRYARSLAVMSMVGSVLGLGDRHLDNLLVDLKYGHVVHIDYNICFDKGKILRIPETVPFRLSRNMRHALGPSDMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDPLVDWTSHDNISTSGGVSLALQLAVYGSSWKAKARERLTDTIELFQLRVTELQALWMSNREDLYHWMKQVTDCLLAEQSIMGMNGAYAQQRVKAGTELREAVARHQALAKEFRPLIRVIGKEKEEFADYLKFYKQAFIDPLLKGHSALRHELDIDTCVQNFNIVMQNIDVVFMSLISLSTMPIDSVSSRASQKQFNAPPGLENVWVLQQEQQENSQAREVVRRVERRLNGWLDGSAPDRKLSPREEADVLIAEATSSANLAQMYEGWTAWV
What is the function of this protein?
Serine/threonine protein kinase involved in mRNA surveillance.  Recognizes the substrate consensus sequence [ST]-Q.  Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2 (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase smg-1, Suppressor with morphogenetic effect on genitalia protein 1.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCL11_MOUSE
Sequence: MQSSTALLFLLLTVTSFTSQVLAHPGSIPTSCCFIMTSKKIPNTLLKSYKRITNNRCTLKAIVFKTRLGKEICADPKKKWVQDATKHLDQKLQTPKP
What is the function of this protein?
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils (PubMed:7568052, PubMed:8574847).  Binds to CCR3 (By similarity).
What are the official names of this protein?
Eotaxin, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GAR5A_BOVIN
Sequence: MKRGHEPKPAFGGAGEAGPGVMAERPLVPACPTGRPGRLQRHLLSGEFDQLRDFRIFESNFVQVTRLGEVANKVTMGVAASSPALELPDLLLLAGPAKENGHLQLFGLFPLQFVQLFVHDESRWQLKVKFRTGRAFYLQLRAPPESRDREFGQWVRLLYRLRFHSAQGAVPFTQDYSALEDDEDDDEDEDRDLPAGELQAMEARLDPQMSELWGL
What is the function of this protein?
RAB2B effector protein which promotes cytosolic DNA-induced innate immune responses.  Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis.
What are the official names of this protein?
Golgi-associated RAB2 interactor protein 5A.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: HUTH_VIBVY
Sequence: MDMLNLTLKPGCLSLNQLRQVSRSPINLSLDASAIPAIEDSTQVVERVIAEDRTVYGINTGFGLLANTRIAPEDLETLQRSIVLSHAAGIGEFMADETVRLMMVLKINSLSRGYSGIRLNVIQMLIDLVNAQVYPCVPQKGSVGASGDLAPLAHMSTVLLGEGQARHNGKIISGLEALKIAGLEPITLAPKEGLALLNGTQASTAFALEGLFIAEDLFASATVCGAMSVEAALGSRRPFDPRIHRVRGHRSQMDSAMAYRHLLDTSSEIGQSHSNCEKVQDPYSLRCQPQVMGACLQQIRNSAEILLVESNSVSDNPLVFAEDDDIISGGNFHAEPVAMAADNLALAIAEIGSLSERRMALLIDSALSKLPPFLVDNGGVNSGFMIAQVTSAALASENKTLAHPASVDSLPTSANQEDHVSMATFAARRLREMGENTRGILAVEYLSAAQGLDFRAPHKSSPRIEQAKQMLREKVSFYDKDRYFAPDIEKANSLLKLAVHNVLMPEALLPSVL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_FRATT
Sequence: MYAIIKNGGKQYKVKEDEVVKLEKFDLGIGEKVEFDTVLMGQTAAGEVKIGAPTVAGAKVVGEVVEQGRHKKVKIMKFRRRKHSMKQQGHRQYFTAVKVSSISL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ABCC9_RAT
Sequence: MSLSFCGNNISSYNIYHGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSQRASRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQLGWGMSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKAIGKLPIAMRAVTNYVCLKEAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNEPKNNTTRFSETLSSKEFLENAHVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDNYEQARRLRPAETEDVAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSSFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINDPGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLIALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK
What is the function of this protein?
Subunit of ATP-sensitive potassium channels (KATP).  Can form cardiac and smooth muscle-type KATP channels with KCNJ11.  KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
What are the official names of this protein?
ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LDH_PEDPA
Sequence: MSKIQNHQKVVLVGDGAVGSSYAFAMAQQGIAEEFVIVDVVKDRTVGDALDLEDATPFTAPKNIYSGEYSDCKDADLVVITAGAPQKPGETRLDLVNKNLNILSTIVKPVVDSGFDGIFLVAANPVDILTYATWKFSGFPKEKVIGSGISLDSARLRVALGKKFNVSPDSVDAYIMGEHGDSEFAAYSTASIGTKPLLDIAKEEGVSTDELAEIEDSVRNKAYEIINKKGATFYGVGTALMRISKAILRDENAVLPVGAYMDGEYGLNDIYIGTPAVINGQGLNRVIESPLSDDEMKKMTDSATTLKKVLTDGLKALEEK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_ECOL5
Sequence: MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMAIAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTERVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFANIEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTERNFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKATAAEFGIELTAIGELVPARGGRAMVEIR
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: PURL_METMA
Sequence: MLPEEDLKIIKKELGREPTLVEQGCFLNLWSEHCSYRSSAPLLKTFTTTGENVIIGPGDDAAIIKFEDGYVLAIGMESHNHPSYVDPYNGAATGVGGIVRDIISMGARPIALMDPLYFGPLDTPKNLFLFEQIIKGIAGYGNCIGVPVVNGETFFDRRYSGNPLVNVVAVGLCKEEKVMTSRSQKAGNKLILAGSSTGKDGLGGASFASRDLSESAEAEDRPSVQVGDPYTEKLVMEMTLEAIDKGYIKSCKDLGAAGLGGASSELAAKGGLGAYIIADAVPQREPEMNAYEILLAESQERMVFEVAPEDVDAVLALVQKYDLNGAVIGHLTEKPNYTVEFRGEIVADIPIGFLTGGAPTCEKPSEAPIHREEGKKPETPEDLKAAFMKVLSSHNIASKEWIYRQYDHEVQLRTVVKPGEDSGVLRITDKKGIALSCGCQPRATLLDPYTGGRTAIIENAMNLAVKGAEGLAIVNCLNFGNPENPETYWQFKNAVLGLGDAARELSIPVVGGNVSLYNESDEFRTAIPPTPSIGMIGKVDLETPLPSGFFAKTGDSIILVGETVPEMGGSEYYSCMGAGNAGKVPEVPKNAPEIIKAVIEAVKSGKLNSAHDISLGGIGAGLARMCKNMGGKVDVSEIAGGMKEDEFLFSEAPARALLATAEPEAVQELLKGVPHAVIGTVGGDALEIKGKDFELFISLEEIKNAHESLTKFMMMG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGAL_VIBVY
Sequence: MTAFSEILQRRDWENPQSVNIHCLKAHSPLASFRDMAHARDGIHAQRQSLNGQWKFKLFDAPEQVDGQFTQADFNDAEWDEIPVPSNWQLHGYDKPIYANIKYPFDVNPPFVPRENPTGCYRTRVSLSPEDLLNTQRIIFDGVNSAFHLWCNGTWVGYSQDSRLPAEFDLTSHLVAGENTLAVMVMRWCDGSYLEDQDMWWLSGIFRDVTLLSKPQHCIEDVFITPDLDACYRDGSLSIVTTIAAPETYQVQVQLFEGTQAVTEPNIDRPHNRRIDERGTWNDVVFQTLHLREPKKWTAETPNLYRLVVSLLDENGTHLESEAYPVGFRKVEISEGQLKLNGKPLLIRGVNRHEHHPELGHVMTEEDMIRDICLMKQYNFNAVRTAHYPNHPRWYELCDQYGLYVCDEANIETHGMQPMSRLSSDPQWAHAYMSRYTQMVLRDKNHPSIIIWSLGNESGHGSNHNAMYAWSKNFDPSRPVQYEGGGSNTTATDIIAPMYARVNTLIADEAVPKWPIKKWISLPNETRPLILCEYAHAMGNSLGSFDEYWAAFREFPRLQGGFIWDWVDQGLSQWDENGQHFWAYGGDFGDEINDRQFCINGLIFPDRTVHPTLQEAKYCQRMITVSLQEQTQKACTLLVTNENLFRATDNEQLNWSLLENGQVIQTGSLALSVEADSQTRLEIALNFTPKAQAQYHLNTDICLIEATSWAPAGHVVATEQMALRNHAGLAIPTLRTQPAPKLTQDGHAIVVSSLDEKHQWRWDSQSGLLMEWNVDGKAQMLAAPQDNFFRAPLDNDIGISEVDNVDPNAWVCRWEMAGIGQWERHCVHCDSETLAHTVVVTTTFAYHFGGDVQAITQWTHTLSNDGEMLLDVDVTLADTLPPMPRIGLELQLPLYQADTPITWQGLGPFENYPDRLAAARFGLHTQTLAQMHTPYIFPTDSGLRCGTQWLQVNELAISGDFQFSVSQYAQQQLAEAKHTHDLLAQERIYLRLDHQHMGVGGDDSWSPSVHKEFQLTEKHYRYQLRFKPASR
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: RDGC_XANOM
Sequence: MFFRNLTLFRFPTTLDFSQIDTLLPPVQLKPVGPLEMSSRGFISPFGRDEQGVLSHRLEDFLWLTVGGEDKILPGAVVNDLLERKVAEIEEKEGRRPGGKARKRLKDDLIHELLPRAFVKSSRTDAILDLQHGYIAVNSSSRKSGENVMSEIRGALGSFPALPLNAEVAPRAILTGWIAGEPLPEGLSLGEECEMKDPIEGGAVVKCQHQELRGDEIDKHLEAGKQVTKLALVLDDNLSFVLGDDLVIRKLKFLDGALDQLEHSEDDGARAELDARFTLMSAEIRRLFLLLETALKLSKAE
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DXR_CLOB8
Sequence: MKNISILGATGSIGSQTLDVIRKSNGELKLIGVTANTSVKKVIEIIEEFKPSYVGMMDAVSTHEIKKYCEEHNKKIKVLEGIEGLDKIASLDEIDMVVTSVVGMIGLEPTMKAIEAKKDIALANKETLVVAGEIVMKAAKENNVKIFPVDSEHSAIFQCLRGNDINTLRKIILTASGGPFRGRTLESLEDIKVEDALKHPKWNMGRKISIDSATLMNKGLEVIEAHWLFNCDYDNIQVVVHPQSIVHSMVEYNDGSIVAQLGAQDMRLPIQYALLYENREKRIADTIDFYEISQLTFEKPDIDTFKALNLAFKAGKAGRLMPTILNGANEAAVELFLDRKIKFLQIADIIERCMEVFKTQANKELTLENIIELDKEVKEYVIKNAVL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GSA_RUBXD
Sequence: MSGLQEARLRLARDRSARLMERAVRRMPGGVNSPVRAFRSVGGDPLFMERGEGPRIFDADGNAYIDYVMSYGPLLLGHAPPEVVGAVERAARRGTTFGAPTRLEVELAELVCEAVPSVEVVRMVNSGTEATMSAVRLARGYTGREKILKFDGNYHGHGDALLVSAGSGVATLGLPDSPGVTPGAARDTAVLPYNDLEAVRELFEERGEEFAAVILEPVAGNMGCIPPEEGFLEGLREITAACGALLIFDEVMTGFRVSRGGAQERYGVVPDLTCLGKVIGGGLPVGAYGGRREIMERVAPAGPVYQAGTLSGNPLAMSAGLATLRRTGEPGFYERLEELGARWERGMREAASGSAVPVTVNRVGSMVSLFFASGPVRDFASAAASDAELFKDFFWHMLSRGVYLAPSQYEAGFISLAHSEEEIDRTVEAAAEWFAGRRA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2204_ARCFU
Sequence: MLKELEVNGKRFFLAPESNFWAIGEREEVERFYRERKDALLEEMQRYRFEVDIRTAYINPTESCNRNCPYCYIPAEIRERGTKMSYEKLEEILTVLAENGVERVIFHGAEPLMVKDEIFRAMEDFDFKYGIQTNATLLEEEDAELLMKKGASVGISLDSPYKETNDYLRGKGHYDAVMRALDFFDGYRSLNIIMTVNKHNFQHLPAMVDFLAGKVSVMLANPVRGTSPGGRELRPPEGFEDYYIKAIDRAIENTKSGRRIVIGDFANILLGLVAPTSRVLQCDISPCGGGRRFFAVSADGIYPCGEFIGMEEFRANLSALSDWSSLIEKFEVVRKRTVEQIEECRNCEFRNLCGAPCPAEIYAESGTMLRKSPYCEFYKKLALKAMDVIARGDVRNVLKLERMKAIYRVEDF
What are the official names of this protein?
Uncharacterized protein AF_2204.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
Protein: RS5_AGRFC
Sequence: MAQEKRGSRDDRQNREERDSEFVDKLVAINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATESAKRDLIFVPLRDGRTLHHDVNGRHGAGKVLLRSAKAGTGIIAGGPMRAVFETLGVHDVVAKSTGSSNPYNMVRATFDALKHQVHPKDIAAQRGLKYATLQARRAASGNASEE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: GYRB_MYCSM
Sequence: MAAQKNNAPKEYGADSITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGFATRVDVKIHADGSVEVRDDGRGIPVEMHATGMPTIDVVMTQLHAGGKFDGETYAVSGGLHGVGVSVVNALSTRLEATVLRDGYEWFQYYDRSVPGKLKQGGETKETGTTIRFWADPEIFETTDYNFETVARRLQEMAFLNKGLTIELTDERVTAEEVVDDVVKDTAEAPKTADEKAAEATGPSKVKHRVFHYPGGLVDYVKHINRTKTPIQQSIIDFDGKGPGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRAALTSVVNRYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVAEPQFEGQTKTKLGNTEVKSFVQKICNEQLQHWFEANPAEAKTVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPSKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQSIITALGTGIHDEFDISKLRYHKIVLMADADVDGQHISTLLLTLLFRFMKPLVENGHIFLAQPPLYKLKWQRSEPEFAYSDRERDGLLEAGRAAGKKINVDDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVEARRSFITRNAKDVRFLDV
What is the function of this protein?
Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_CHLPD
Sequence: MLAKDFLFMKNIRITIEYDGTGYAGWQRQAGSFCTVQGEIERILSQILQEDIRLAGAGRTDKGVHARAQIATFKSRSSLGPDRMVHSMNALLPNTIRISDPLVVPEGFHARHSAKEREYRYFVREEPSAVLGRFSGCSYGSLDLMSMNRVASYVLGEHDFSVFSKETRDRTGCLCRVISCKWFRQREFFVLRISANRFLRSMVRYLAALMIDSGKGLLSPEEAREMIESGILTRQLVPAAPNGLFLWKITYGSDSHSF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MTNA_GEOSL
Sequence: MSFRTIEWRDDKVVMIDQTRLPGEEVYCEYADYKSVAEAIRGMVIRGAPAIGVAAAMGVALGAREIIADTYESFFRQMENVCDVMARTRPTAVNLFWAIERMKRVADENRDKPLDQLREILKTEAIRIEQEDLELCKAIGRHGAALIPEGATVLTHCNAGGLATAGYGTALGVIRAAHDAGKKIQVFADETRPWLQGARLTAWELMKDGIPVTLISDNMAGFFMKRGEIACCVVGADRIAANGDTANKIGTYSVAVLAKENNIPFYVAAPTTTLDLSLENGDQIPIEERHSREVTHLHGFPVAPEGIRVRNPAFDVTPARYISAIITEQGVVSGDYVTGLRGLVAP
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: DPO4_ECOHS
Sequence: MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFSELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVILLKRFGKFGRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_BUCAP
Sequence: MSQGILFIISAPSGTGKSSLIEGLLKTKFLYNIQVSISHTTRVMRPGESHGKHYYFISKKEFRIMIKQESFLEYAKVFNNYYGTSRQSIEKMLLSGIDVFLDIDWQGANQIRYKMPNSKSIFLLPPSKDELYKRLRERGQDSDTVISKRMEKAVDEMNHYSEYDYLIINDDFQKAINDLRTIIIAEHLCLFHQKNKHNVLISQLLKS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_ECOLU
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_STRZJ
Sequence: MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVGGENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: K1C27_RAT
Sequence: MSVRFSSASRRLGSVRLSSPGAALGAGNTCGVPGIGSGFSCAFGGSSLAGGLGMGGASCGAFTVNEHGLLSGNEKVTMQNLNDRLASYLENVQALEEANADLEQKIKDWYEKFGPGSCRGLDHDYSRYFPIIDDLRTQIISATAQNANIVLQNDNARLTADDFRMKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLSEELAYLKKNHEEEMQALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFQEKSASLQQQISDDAGATTSARNELTEMKRTLQTLEIELQSLLAMKHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQKLEYEQLLNVKAHLEKEIETYCLLIGGDEGSCVKSKGQGGPGNQTKDSPKTAIVKTVVEELDPRGKVLSSRVHTLEEKSTKVNNKNEQRIPS
What is the function of this protein?
Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs).
What are the official names of this protein?
Keratin, type I cytoskeletal 27, Cytokeratin-27, CK-27, Keratin-27, K27, Type I inner root sheath-specific keratin-K25irs3, Type I keratin KA40.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_ACIBC
Sequence: MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMSKWMAKKTTGTELIDPNAPRNQAESWLLQTVAELSQRAGINMPEVGIFPSYQSNAFATGWNKNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTLALIQGVVNAFVMFFARVVGDFIDRNVFGRQDNEAPGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQAMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDCP
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLPE_HAEDU
Sequence: MAAIFTEISPTTAWQLVKHENAFLADIRALAHYLDDHPSGAFHLTNDSYAEFLDLVSDEQAVIVVCYHGISSRSVAQFLVEQGFETVYSVTGGFEAWQKLALPVTKGCDQ
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL3_CYBJA
Sequence: YGIHCNTLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase-3, Transaldolase III.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.