PharMolix/UniProtQA huggingface dataset:
Protein: M1_I56A1
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVTSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQIVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAERMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQIQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: RIMO_XANAC
Sequence: MSQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGCLGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGDLVSRPVDEVLREAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRLYQTRMKALCEGLSELGVWTRLHYVYPYPHVDDVIGLMAEGKLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRSTFIVGFPGETDAEFESLLDFLDQAQLDRVGAFAYSPVDGASANALPDQVPEEVKQERLARFMAKQAQISALRLESKIGSVQQCLVDVIEDDIAVARSRADAPEIDGLVHIQNGGELGLKVGDLVDVEITDSDEHDLFGDALPSGHAVQPGRTLNLQIV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y0574_MYCTO
Sequence: MAGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPVDWRWPWGEALAVLENTATDVCLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHVCALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAARRSALVTVGHERRVIVGSVAAESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGYATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESFRSELRLLYLTVTDPASGNLISLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRVVTRPDNLLEVVPAANLTSKE
What is the function of this protein?
Could be involved in the biosynthesis, transport or localization of poly-alpha-L-glutamine (PLG), a cell wall component.  Contributes to stress tolerance and virulence.
What are the official names of this protein?
Probable polyglutamine synthesis accessory protein MT0602.
What is the protein family that this protein belongs to?
Belongs to the CapA family.
Protein: PSMA3_STAA9
Sequence: MEFVAKLFKFFKDLLGKFLGNN
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 3 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: DXR_PROM9
Sequence: MKYITVLGSTGSIGTQTLEIASEQPDKFKAVALSAGRNITLLTEQVKTHKPEVVAIEDENLIEDLKDNINNLDLDSAPLVLGGKEGINAVAAWDKADTVITGIVGCAGLIPTMSAINAGKNIALANKETLIAAGPIVIPALKKNNSRLLPADSEHSAIFQCLQGLPNYENADFSTGVMPKGLKAIHLTASGGAFRDWPVENLKHVTVEDATSHPNWDMGKKITVDSATLMNKGLEVIEAHYLFGTSYENIEIVIHPQSIIHSMIEMEDSSVLAQLGWPDMKLPILYAMSWPERFKTNWKRLNLSEIGKLTFKEPDEFKYPCMGLAYAAGKSSGTMPAVLNAANEMAVEQFLKEKISFQEIPTFISKACESHMENLNLSPELEDILEVDNWARIFVKQEIKKGKKYVSI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RECR_NEIG2
Sequence: MMNSKKQDAFQRLIGALKVLPNVGPKSAQRMAYHLLQQKRKEAEELVDALQTALRQVRHCARCNTFCEGGLCDICADETRDGRRLMVVHMPADVSNIEAANCHDGLYFVLMGQINTALGMDVSAIALDRLAQRLDGGEIEEIIIATAFTAEGNATAYVLSEFFKNLPYKVSRLSQGIPLGGELEYVDAGTLAQAVYERRLIKEGGA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ILVC1_STRCO
Sequence: MAELFYDADADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLHEGSKSKAKAEEQGLRVVPVAEAAAEADVIMILVPDPIQAEVYEKDIKDNLKDGDALFFGHGLNIRYGFIKPPAGVDVCMVAPKGPGHLVRRQYEEGRGVPCIAAVEQDATGNAFALALSYAKGIGGTRAGVIKTTFTEETETDLFGEQAVLCGGTAALVKAGFETLTEAGYQPEIAYFECLHELKLIVDLMYEGGLEKMRWSISETAEWGDYVTGPRIITDATKAEMKKVLAEIQDGTFAKNWMDEYHGGLKKYNEYKKQDSEHLLETTGKELRKLMSWVDEEA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)) 1, KARI 1, Acetohydroxy-acid isomeroreductase 1, AHIR 1, Alpha-keto-beta-hydroxylacyl reductoisomerase 1, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: US03_HHV2H
Sequence: MACRKFCGVYRRPDKRQEASVPPETNTAPAFPASTFYTPAEDAYLAPGPPETIHPSRPPSPGEAARLCQLQEILAQMHSDEDYPIVDAAGAEEEDEADDDAPDDVAYPEDYAEGRFLSMVSAAPLPGASGHPPVPGRAAPPDVRTCDTGKVGATGFTPEELDTMDREALRAISRGCKPPSTLAKLVTGLGFAIHGALIPGSEGCVFDSSHPNYPHRVIVKAGWYASTSHEARLLRRLNHPAILPLLDLHVVSGVTCLVLPKYHCDLYTYLSKRPSPLGHLQITAVSRQLLSAIDYVHCKGIIHRDIKTENIFINTPENICLGDFGAACFVRGCRSSPFHYGIAGTIDTNAPEVLAGDPYTQVIDIWSAGLVIFETAVHTASLFSAPRDPERRPCDNQIARIIRQAQVHVDEFPTHAESRLTAHYRSRAAGNNRPAWTRPAWTRYYKIHTDVEYLICKALTFDAALRPSAAELLRLPLFHPK
What is the function of this protein?
Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and inhibition of host immune response.  Phosphorylates UL31 and UL34, two critical regulators of capsid budding from nucleus to endoplasmic reticulum, thereby facilitating virion egress.  Modulates and redistributes host components of the nuclear envelope, including LMNA, emerin/EMD and the nuclear matrix protein MATR3.  In turn, facilitates nuclear pore impairment and capsid release through impaired nuclear envelope.  Phosphorylates envelope glycoprotein B (gB), probably to direct it to the cell surface.  Promotes virus intracellular spread by restructuring host cell cytoskeleton.  Blocks host apoptosis to extend cell survival and allow efficient viral replication.  Promotes viral gene expression by phosphorylating host HDAC2 to reduce viral genome silencing.  Strongly inhibits TCR-activated signal transduction in T-cells by reducing the ubiquitination of LAT and TRAF6, leading to a suboptimal activation of LAT.  Subverts host antiviral innate immunity by inhibiting type I interferon production through hyperphosphorylation of beta-catenin/CTNNB1.  In addition, phosphorylates the RNA sensor RIGI and the transcription factor IRF3 to prevent the RLR-mediated antiviral signaling pathway.  Hyperphosphorylates host RELA and thereby dampens NF-kappa-B signaling.
What are the official names of this protein?
Serine/threonine-protein kinase US3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: NCAP_RINDL
Sequence: MASLLKSLALFKKNKDKPPLAAGSGGAIRGIKHVIIVPIPGDSSITTRSRLLDCLVKMVGDPDISGPKLTGALISILSLFVESPGQLIQRITDDPDISIKLVEVIQSDKTQSGLTFASRGASMDDEADRYFTYDEPNGGEERQSYWFENREIQDIEVQDPEGFNMILATILAQIWILLAKAVTTPDTAADSELRRWVKYTQQRRVIGEFRLDKGWLDTVRNRIAEDLSLRRFMVALILDIKRTPGNKPRIAEMICDIDTYIVEAGLASFILTIKFGIETMYPALGLHEFAGELSTIESLMNLYQQMGELAPYMVILENSIQNKFSAGAYPLLWSYAMGVGVELESSMGGLNFGRSYFDPAYFRLGQEMVRRSAGKVSSNLASELGITEEEAKLVSEIAAYTGDDRNSRTSGPKQTQVSFLRTDQGGEIQHNASKKDEARVLQVRKETWASSRSDRYKEDTDNEAVSPSVKTLIDVDTTPEADTDPLGNKKSAEALLKLQAMASILEDPTLGNDSPRTYNDKDLLS
What is the function of this protein?
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: YUSW_BACSU
Sequence: MHLIRAAGAVCLAVVLIAGCRFNEDQHQAEGENTAVTQLKSVPYSNFSLRVSYGDGEHNRYEGIYTKNGTQEKAEIQDKLSGVNQEGEEALDEMKMILSELSVTDQMAETEVIHSVLAAFNLDSHYDHIDLKLKLKDGSIREIKK
What are the official names of this protein?
Uncharacterized protein YusW.
Protein: NUOI_CHRVO
Sequence: MNSIRNFFKTFLLVELVKGLMVTGRYFFARKITVQFPEEKTPISPRFRGLHAQRRYANGEERCIACKLCEAVCPAMAISIESEQREDGTRRTSRYDIDLTKCIFCGFCEEACPVDAIVETHIFEYHGEKRGDLYYTKPMLLAIGDKYEAEIAANKAADAKYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYC_HALSA
Sequence: MTQYVSNTRSGEQEAFEPDDPENVLVYTCGLTVSDDAHLGHARLWVQSDVMTRWLSHAGYGVRHVQNVTDVNEKIVARVGADGLGDTEAAVAAHYTQSVIDDMRALNLARADVYPRVSEHVPEIIDLIGDLVDAGYAYEAGGSVYFDVRRFEEYGALSGQQVDELDPQGPDAEQAEKRHPADFALWKAGGVSPDDANTHRDDELPPLDGERGQTWASPWGEGRPGWHIECSAMAMTHLDDHIDIHVGGQDLVFPHHENEIAQSEAASGERFADHWLHVRLLETDGEKMSSSLGNFFTVSNAVAERGPNVVRMLLVSTSYTQRQTYSEATVSEATQRWERLQRAHERAADAIDSVAAHAKPADDALRTAVADARGEFAAAMRADFNTRAAVSALLELASAVNRHVDGTDTYDYQGLHDAVDAFETLGGDVLGLQFDDGAGEDAVSLADDVIDLVLDVREQERTAGNYERADDLRDRLEALGVSVEDTDDGATVRR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSR3_VULDI
Sequence: MIPRVFIYRLPQDDPRKNTAIKLVRFGFAQLVDSIKALPSGSIILDPTVKTPLTPSDRVIAESRGLSLIDCSWKRAVDVHTKFIRGKFIRRRLPLLIAANPTHYGKPYILSTIEAVAAALYIMGFKDEAMEVLRLYKWGPNFIIINQKYLERYAAGDLSPERELLGVDDVDNGLEQLMRVLTNGD
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
What are the official names of this protein?
16S rRNA aminocarboxypropyltransferase, 20S S rRNA accumulation protein 3 homolog, VdTsr3.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STUA_PHANO
Sequence: MNQMQSYADVHPPHMSAATAHAPASAAPSGISHYAYPPQSSMMQPGQHQYGPTPPGYPSYGYSNGVPSGLPASSSMNNAMVPSTLQLPAMSSSGPSPSLSGAQSYAPHSFDHTGQVAPPGMKPRVTATLWEDEGSLCFQVEAKGVCVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKTRHVVKIGPMHLKGVWIPFERALEFANKEKITEQLYPLFVHDIGALLYHPSNQTRASVGSAAMAAVDRRRPDSMQTQRYISGPTTSQPPSLHHHHSMSNPIGAPMSQAPHALQPHPSAGRPGLDRAHTFPTPPTSASSIMGMSNSGSSYEWSGANVQTPQGSQPLSIDTGLSNTRSVPTTPATTPPGAVQQAISYGSNQSYDNSRPMYSGPPSQPGQYNTQGQSMMGYRPDSGYTKTEMAPPSRLADVSEEGDVKHSEGMMPQGNSQVVAPAPGPEGDHEHDNEYTHSTASYNGSRGPYGYASNGNAGGLHPEHPHMSPEMNGSPHQNGSGRATPRTTTTSQTQWNSGYPTPQRQGPPSSNLYNVMSDPRGAPNGNAPHDAYPGPGAVPQYASQGYPPANGNAKRGRDDDDEDPYRPDSVQSDDMGGLKRRKTMEGGAVGGAYAQDPTPGLQRAHTMTAQRARR
What is the function of this protein?
Transcription factor that regulates asexual reproduction (PubMed:20495056).  Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).  Required for pathogenicity and positively regulates the synthesis of the mycotoxin alternariol (PubMed:20495056).  Acts as a positive regulator of Tox3 but is not required for the expression of ToxA (PubMed:20495056).  Acts also as a central regulator of carbon metabolism including glycolysis, the TCA cycle, and amino acid synthesis (PubMed:20495056).
What are the official names of this protein?
Cell pattern formation-associated protein StuA, Stunted protein A.
What is the protein family that this protein belongs to?
Belongs to the EFG1/PHD1/stuA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRO_ADEB3
Sequence: MGSREEELRFILHDLGVGPYFLGTFDKHFPGFISKDRMSCAIVNTAGRETGGVHWLAMAWHPASQTFYMFDPFGFSDQKLKQIYNFEYQGLLKRSALTSTADRCLTLIQSTQSVQGPNSAACGLFCCMFLHAFVRWPLRAMDNNPTMNLIHGVPNNMLESPSSQNVFLRNQQNLYRFLRRHSPHFVKHAAQIEADTAFDKMLTN
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: DNLJ_PROM4
Sequence: MEQNSSNLSKRSFELRKLLNRANHAYYVLDTPLMEDTVYDRLYRELLNIEKNHPSLITADSPSQRLGSTPAKEFVKVEHKIPLMSLDNAFNFEELQDWDLRIRKLLNQKNNFGILKTSIDFACELKIDGSALALSYANGVLVQAATRGDGVAGEEITANVKTITSIPLSLDIENPPSWLEVRGEAFLPKQTFDGINLLRKQQREALFANPRNACAGTLRQLDPQIVASRQLDFFAYKMYLPKDWDPQGENIHQPEAQDAALKWLKKAGFKVNPNTKIFKSLHEVQSFFDIWEKKRHKLPYTTDGVVVKVNNFKLQEMLGVTQKSPRWAIALKYPAEEAPTKLINLSYQVGRTGTVTPVAEFEPIPLAGTIVRKATLHNADRLQSLDLHNEDTIVVRKAGEIIPEVVCVLKELRPQNSTRLYLPSNCPECDEKLVRGTDQAATKCVNNLCPAIIQGALRHWVSKKAMNIDGVGSKVIEQLVNKGIVKSIPDLYELNYQMLFGLERMGEKSAHKVIESIEKSKTQPWNKQLYGLGILHIGEGNAKLLANAFASEDELSHAAINSPERIAKIHGIGNEMVESLQEWFEDESNQRIISRLKELGVQLKSTANDSGAIKSVINSSNKEVLGKRFVLTGTMESINRDVAQEMIEKAGGKVNSSISSKTTYLITGSNPGSKLSKAKELGIKIINEEDFFNLLSK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL27_CAMHC
Sequence: MAHKKGQGSTQNNRDSIGRRLGVKKFGGEFVRAGNIIIRQRGTATHAGNNVGIGTDHTIFALIDGVVKFERFDKTRKQVSVYPLS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ERD2A_ARATH
Sequence: MNIFRFAGDMSHLISVLILLLKIYATKSCAGISLKTQELYALVFLTRYLDLFTDYVSLYNSIMKIVFIASSLAIVWCMRRHPLVRRSYDKDLDTFRHQYVVLACFVLGLILNEKFTVQEVFWAFSIYLEAVAILPQLVLLQRSGNVDNLTGQYVVFLGAYRGLYIINWIYRYFTEDHFTRWIACVSGLVQTALYADFFYYYYISWKTNTKLKLPA
What is the function of this protein?
Required for the retention of luminal endoplasmic reticulum proteins.  Determines the specificity of the luminal ER protein retention system.  Also required for normal vesicular traffic through the Golgi.  This receptor recognizes H-D-E-L.
What are the official names of this protein?
ER lumen protein-retaining receptor A, HDEL receptor.
What is the protein family that this protein belongs to?
Belongs to the ERD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RAPA_SHEWM
Sequence: MPFSLGQRWISDTESELGLGTVVAVEGRMVTVMFPATDENRMFSRADAPLTRVIFNPGDKAESHEGWSLTVSEVEEKDNLIIYHGIHDETGEQVSLRETLLNHNIRFNKPQDRLFAGQIDRLERFGIRYQCQQLRHKLATSDMLGLQGPRVGLIPHQQWIAHEVGRRFAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERILVIVPDTLRHQWLVEMLRRFNLKFSVFDEDRCVEAYADSDNPFYTEQLVICSLELLRKKRRLDQALAADWDLMVVDEAHHLEWTEDAPSRAYRIVEALSEEIPGVLLLTATPDQLGHQSHFARLRLLDPDRFYDYEAFLKEETNYADIASTADALAGNEPLSQEIIDNLKTQLAEKDITAATDIIQATDADVDQQQAARDALLQDLLDRHGTGRVLYRNSRASVKGFPTRIFNQYPQKMPAQYVTAARVGAMMNGHLDTAGKVKQALSPEKIYQEFESSSASWWKFDPRVDWLIDFLKENRREKVLIIASQAETALSLEEALRTREGIQATVFHEGMSIIERDKAGAYFAQETGGAQALICSEIGSEGRNFQFASQLILFDLPLNPDLLEQRIGRLDRIGQNNDVSIHVPYLEDTAQESLMQWYHKGLNAFEQTCPSGHILFNEFSESLLNVLISQDKEVLEQVLSDTQTRYAELKSVMEQGRDKLLEINSHGGERANKLVNALAERDEDTNLIGSVIRLWDIIGVEQEDSGENAIVLRPSEHMMFPTYPGLPEDGITVTFDREMALSRDDIALITQEHPLVQTGLDLITSSETGTTSVAVLKNKSLPAGTIFLELIYMADASAPKSSQLYRYLPPTPVRVLLDKNGNNLADNVNYESFNKQLSAVNRHIASKLVNASQAVLHPLFAKGEEFASSELTLLTESSRAKMTTQLNGELERLEALKAVNPNIRDEELAHLREQMVELNGYLDGAVLQLDAIRLVLVSHA
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: MSD5_DROME
Sequence: METNVDFSSISSKLYRKYAQHVRNLKDVCVSKTVMKPGAFFDSLQQMMEEEAAATTPPRDLSSVADYAELFKTLEEYPANLQKMPKKRELQRTNSTLLRGADESVAMGINTSNVSLSLTRLEEQRSAVDVYNDFKGFQRKLAKIYDEAAALDTTESIYKQKLTQLHGFAQQLEKLMPTGGESPPDAFTSEQQEKLLTIAANMEQLNYLRSNSLQLPNPNEILATGSLAARLEMFVEVLTYTLLQVSSYNMAMI
What is the function of this protein?
As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules.  The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules.
What are the official names of this protein?
Augmin complex subunit msd5, Mitotic spindle density protein 5.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle.
Protein: PETN_CYAP4
Sequence: MDILTLGWVGLLGLFTYSIAMVVWGRHGM
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: UBIA_XYLFA
Sequence: MAYERFTSAITLLMHWRNRLDPYWKLARGDRPVGFLLLLWPTWWALWLAAGGVPPWWTLCVFTTGIWLTRSAGCVINDYTDRWLDPHVERTRIRPLVTGAVSPRNALLMFATLMLIAFGLVLTMNQLTVLLSVVGLFLAMTYPYLKRYTYLPQVYLGLAFGWGIPMAFAAIQGKVPTQAWLLYVANILWTTAYDTWCAMVDRDDDIKMGAKSTAILFADLDLTVQGVLYTLMLFTLCLVGLRATLSHTYWISLIAAVALIGYQFIIARRREPTACFRAFMHNNWVGMTIFAGIALATTH
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NLPA_ECOLI
Sequence: MKLTTHHLRTGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQDVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGYKLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKEGKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVHDSVFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW
What are the official names of this protein?
Lipoprotein 28.
What is the protein family that this protein belongs to?
Belongs to the NlpA lipoprotein family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: RL4_BACC0
Sequence: MPKVTVYNQTGSQVGEIELAEAIFGIEPNEAVLFEAVMMQRASLRQGTHKVKTRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGTVFGPTPRSYAYKLPKKVRRLAIKSALATKVVENNIVVLEDLVLNAPKTKDMLAVLKGLTVEKKALIVTADANESVELSARNIPGVTVITADGVNVLDVLHHDKLIMTKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RL15_METVA
Sequence: MIRKSKKITKQRGSRTCGYGEAKKHRGAGHRGGRGNAGHQKHKWLSVCKFNPEYFGKYGFNRNPCLIKKLETINVGELEEYVLKYKDAFKLKDGKVVVNATEIGFEKILGKGRISTAMVVKAVEFSEGAKEKIEAAGGEFVEL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.