PharMolix/UniProtQA huggingface dataset:
Protein: CI072_HUMAN
Sequence: MSTLCPPPSPAVAKTEIALSGKSPLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEITFLANHTLNGEILRNAESGAIDVKFFVLSEKGVIIVSLIFDGNWNGDRSTYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKIILEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERKCSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSELTAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFQLKPGLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQKGKKPFKSLRNLKIDLDLTAEGDLNIIMALAEKIKPGLHSFIFGRPFYTSVQERDVLMTF
What is the function of this protein?
Does not play a role in regulation of stress granule assembly in response to cellular stress.
What are the official names of this protein?
Guanine nucleotide exchange factor C9orf72.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, P-body. Cytoplasm, Stress granule. Endosome. Lysosome. Cytoplasmic vesicle, autophagosome. Secreted. Cell projection, axon. Cell projection, growth cone. Perikaryon. Note=Detected in the cytoplasm of neurons from brain tissue (PubMed:21944778). Detected in the nucleus in fibroblasts (PubMed:21944779). During corticogenesis, transitions from being predominantly cytoplasmic to a more even nucleocytoplasmic distribution (By similarity). SUBCELLULAR LOCATION: [Isoform 1]: Perikaryon. Cell projection, dendrite. Presynapse. Postsynapse. Note=Expressed diffusely throughout the cytoplasm and dendritic processes of cerebellar Purkinje cells. Also expressed diffusely throughout the cytoplasm of spinal motor neurons. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus membrane; Peripheral membrane protein. Nucleus. Note=Detected at the nuclear membrane of cerebellar Purkinje cells and spinal motor neurons. Also shows diffuse nuclear expression in spinal motor neurons.
Protein: RL10_CARHZ
Sequence: MKPIIEQKAKVVAEIEEMIKSSQAAILVDYRGLTVAEMTELRRKLKEKGAEIKVVKNTLAKRAAHNLGITGLDPYLEGPTALAVAKEDPASAAKVLFDFAKDHPNLEIKVGILENIVLEKDQVKAIADLPPRNVLLAKLLGGMQAPLYGFAGALAGMLRKFVYALEAIRKQKAGEE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SUCC_PSEMY
Sequence: MNLHEYQGKQLFAEYGLPVSKGFAVDTPEEAAEACEKIGGSEWVVKAQVHAGGRGKAGGVKLVKSKEDAKAFAANWLGKRLVTYQTDANGQPVSKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKVAHETPEKILKATIDPLVGAQPYQGRELAFQLGLEGDQVKQFTHIFVGLAKLFQDYDLALLEVNPLVIKADGNLHCLDAKINIDSNAMYRQPKLRAMHDPSQDDPREAHAQKWELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKVLADSGLNIIAATSLTDAAQQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: TRUB_PARDP
Sequence: MARKKGREIHGWLIVDKPAGIGSTDVVGKVRWALDAKKAGHAGTLDPDATGVLAVALGEATKTVPILTDALKAYDFTVSWGAETSTDDASGGVVKTSDARPDEAAIRAALPEFTGEIMQVPPAVSAVRVDGARAYDLAREGEVVELAARPLWVESLELLGAARDSAELRMVCGKGGYVRSIARDLGRKLGCLGHVAQLRRIWSGPFEAGDGFAFDRIDRANQAEIEAALLPLQAALADLPEMQATEIGATRILNGNPGQVLGHAEFGEEVWVSRNGRALCIGRYMGGEVQPSRVFNLG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: BI2L2_DANRE
Sequence: MSGVNSDLLHRSTLSVYNNLMDQFNPGLQKLVTLGNSYIKAFQALALTSEAYFSALAKMGEQALSTLSSRSLGDVLIQISETQRKLTAEAEGVFRWFHVEVLQAMDKNVKLDEEYIEGSRRVYELEVRNQAASLERQLRRGAFRDSLESSEYMQYLRQSQHEILKEEERRYRFLAEKHCGLTQSLLYLINKTGVSLQQRADGWKEKVSESRSSRPRTPTPLDQEAQLKSSVGSLLQTGDREMDREPLGRVPSRAPSPLPSRSRSSSVGESLGLGGGRSMRAIVSHPASSNPVLLPFARGDLLTVLIPEPRNGWLYGRHDPSLRQGWFPAAYVASTEDFLPVGLSISHRSHSMNNLLEPTSQSESDTQTYSEVSSPVVSMRRASADVRSVSPLPEKKTESNNELKSGQKVFHEIPAPATQLRRGSADVRSISPLPDRRAESHFESKVELKNYNELPPPAPPLPNSPLPERKTDLTSERPSTQGQPPEHPLFPRGSNPFATVKLRPTVTNDRSAPRIQ
What is the function of this protein?
Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures.
What are the official names of this protein?
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2, BAI1-associated protein 2-like protein 2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YAJD_ECOL6
Sequence: MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTVHHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYNPFADLKAMMNKKK
What are the official names of this protein?
Putative HNH nuclease YajD.
What is the protein family that this protein belongs to?
Belongs to the HNH nuclease family.
Protein: Y3737_CAUVN
Sequence: MADGVAVTLVVRLTPRGGRDAAEGWALDADGRLYLKVRVASPPVEGAANAALIAFLAKTLKIPRSAVRLAAGETARLKRLELEGVDPADVARAFGPPN
What are the official names of this protein?
UPF0235 protein CCNA_03737.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RECR_BIFAA
Sequence: MALAYDGAIQRLIDAFANLPGIGPKGAQRIAFYLLNAPDEESQALIDAITEVKEKVRFCDICGNVCETSPCPVCADPRRDHSVICVVEEPKDVMSIERTREYRGMYHVLGGVINPMANVQPSDLNIAKLIERLKDSEVKEVILALNPNVEGEATTSFLSQLLSQTDIKVTRLASGLPVGGDLEYADEITLGRALAGRRAV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PYRF_STRPF
Sequence: MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQAIKAEWAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SYGA_SALHS
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRE1B_ARATH
Sequence: MENQESDEPMQKKPHLLDSVSPNSMARNSSPSHPIAKSVSFFDCDFSLLCLRLVDYEIDVDATVLQLQNQKLVQQLDLQKKQLYDVESKIQELQLNQTSYDDELISVNQLWNQLVDDLILLGVRAGANQEALNYLDIVDKKRVPPCAADETFLCRLLQVDSLDTSKSDEVVRKVEEALALRHSSTMELMGLFENTIDTQKTKAESISQSLHAVKSTEDATIQLSSINDLMKEESKNLREMIDALHVRHKEHSEQIQAYISSHSTDQSELKHLKGQLEEIKAELEENRRKLITLKMQKDAACEGHVTSPAIANGSLSPEKPVDKTKLRELKDSIDEIKIMAEGRLSELQASQEYNLSLSRQCQDIENELKDDQYIYSSRLYSLINDRIHHWNAELDRYKILTEAIQAERSFVMRRDKELNLRAESLEAANHKTTTVGSRIEVLEKKLQSCIIEKNGLELETEEAIQDSERQDIKSEFIAMASTLSKEMEMMEAQLKRWKDTAQDALYLREQAQSLRVSLSNKADEQKGLEDKCAKQMAEIKSLKALIEKLLKEKLQLQNLASICTRECNDDRGLAEIKDSQRKAQAQAEELKNVLDEHFLELRVKAAHETESACQERLATAKAEIAELRTQLDLSEREVLELKEGIKVKEQEAEASIAEMETIGQAYEDMQTQNQHLLQQVAERDDYNIKLVSESVKTKHAYNTHLSEKQVMEKQLHQVNASVENFKARIAHNEEQMKGCFSEAYKLIQEDRHLVISLETTKWEVADADKEFRWLKSAVSSSEKEYEQISRRTDDIKLELDDERREKKKLEEELMELNKELEELGSESVEAAIVRLQEEVKNCKNILKCGVCFDRPKEVVIVKCYHLFCQQCIQRSLEIRHRKCPGCGTAFGQNDVRLVKM
What is the function of this protein?
E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1.  H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me.  It thereby plays a central role in histone code and gene regulation.  Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6.
What are the official names of this protein?
E3 ubiquitin-protein ligase BRE1-like 2, Protein HISTONE MONOUBIQUITINATION 2, AtHUB2, RING-type E3 ubiquitin transferase BRE1-like 2.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: INVO_OTOCR
Sequence: MSQQHTLPVTLPPALRQELLGTLSPPAAAQQEQRKQPTPLPTACQKVGSELPGEVPSKHEEKGTDPVKGVLEQECGQQEPELHLGKQQDVHLMKRQDPQEPELHLGKQPEPEGPEPHLGKEQQHQESQDPELHLGKQQQQESQEQELYPGKQQEPQDPELHLGKQQQQESQEQGLCLIKQREPQESQEQRLHLGKEQESQEQRLHLGEEQASQEQRLHLGEEQASQEQRLHLGEEQASPEQRLQLLPQGPQEQELHLGKQQQQQESQQHQEQHEEHQKAEDLGQQHRQEKAQREQQLEEQLDEGKKLLDQQLDQEAVKRHEQLQRDEQFGMKKEQLLEPPGQQKGQLEKPVFVPVPGQVQDIQPAQTAKGEALLLPEQPQEPEV
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Involucrin.
What is the protein family that this protein belongs to?
Belongs to the involucrin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: IF2B_METAC
Sequence: MYDYEELLNRAMAKMPDTETTDARFVIPEPKLFSEGKTTILDNFGNIADTLNRDPDHLMKYLTRELGTAGKIEGTRAVFQGRFTRAQISDNIQAYVDEYVMCSECGRPDTQLVRVDRVLVLKCSACGAHRPVKKRKVSNVVVRDAIEEGGTYELRIDAVGSKGDGIAKIDKYTVFVPGAAKGDVVKVKIKKISGNLAFSEKV
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: BTUD_YERPE
Sequence: MMLLQLNNVSVGTRLASFSSQVTTGLQIHLIGPNGAGKSTLLASLAGLLPASGEIVLAGKSLQHYEGHELARQRAYLSQQQSALSLMPVFQYLSLYQPAGANSQAVATAISYICNKLRLTDKLPRMLSHLSGGEWQRVRLAAVFLQVWPDINPDSKLLLLDEPYSGLDVAQKVALDALLVEFCRSGRSVIISGHDLNHTLQQADEVWLLAQGQVLVQGETQQVMRADVLSQVFEVDFQIHNFNKQQWITTRSV
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DGOD_XANC5
Sequence: MKITRLTTYHAAPRWLFLKVETDEGITGWGEPVIEGRARSVEAAVHELAGYVVGKDPARINDLWQTLYRAGFYRGGAILMSAIAGIDQALWDIKGKTLGVPVYELLGGLVRDRMKTYRWVGGDRPGAIIQQITDYRALGFDTFKFNGTEEMKLIDSARAVDAAVVKVAEIREAFGNSIDFGIDFHGRVGAPMAKALLRELEPFKPLFVEEPVLAEQAEYYPRLAASTSIPLAAGERMFSRFEFKNVLCAGGIGMVQPDLSHAGGITECVKIAAMAEAYDVGFAPHCPLGPIALAACLHVDFVSHNAVLQEQSIGIHYNEGADLLDYVINKDDFHCVDGSIAALPKPGLGVEIDEEMLKRTNENPPDWRNPVWRHSDGSIAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: RS5_HAEDU
Sequence: MSNIEKQAGELQEKLIAVNRVSKTVKGGRIMSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNEGTLQHPVKGSHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINVVRATIDALANMKSPEMVAAKRGKTVEEIWG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RS18_NEIG2
Sequence: MARQSFKRRKFCRFTAEKIQEVDYKQVDLLKDFISENGKIIPARITGTKAFYQRQLAVAVKRARFLALLPYTDQHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ILVD1_STAS1
Sequence: MRSDMIKKGDQQAPARSLLHATGALDKPTDMNKPFVAICNSYIDIVPGHVHLRELADIAKEAIREAGAIPFEFDTIGVDDGIAMGHIGMRYSLPSREIIADAAETVINAHWFDGVFYIPNCDKITPGMLLASVRTNVPAIFCSGGPMKAGLSSEGKALTLSSMFEAVGAFKDGSISKDEFLDMEQNACPTCGSCSGMFTANSMNCLMEVLGLALPYNGTALAVSDQRREMIREAAFKLVDNIKNDLKPKDIVTREAIDDAFALDMAMGGSTNTVLHTLAIANEAGIDYDLTRINEIAKKTPYLSKIAPSSSYSMHDVHEAGGVPAIINELFKKEGTLHPDRITATGKTLRENNEDKEILNSDVIRHLDNPYDKQGGLSILYGNIAPKGAVIKVGGVDPSIKVFKGKAICFDSHDEAVEAIDNHDVREGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAAAGGPIGLINDGDEITIDLTNRTLDVNVSTEELDARKQNVKPFKAKVKTGYLARYTALVTSANTGGIMQVPENLI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 1, DAD 1.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RBFA_BRUME
Sequence: MARSHDTKGSGGLSQRQLRVGEQVRHALAQVLQRGEIRDDLIERTVISVSEVRMSPDLKIATCFITPLGSADPQAVIKALASHAKFIRGRVAPSLAQMKYMPEFRFRPDTSFDNFSKIDALLRFPEVARDLSHDDDEDGGADEAPRNGDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNPC_PSEAU
Sequence: SGSKTAEIGDGCFGVPIDHIGSTSGMGCGRPRPKPTPGGS
What is the function of this protein?
Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity (By similarity).  Recombinant PaNP-c inhibits the angiotensin converting enzyme (ACE).
What are the official names of this protein?
Natriuretic peptide PaNP-c.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_LEUMM
Sequence: MKRTYQPKKRHRERVHGFRKRMSTSNGRKVLARRRAKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LEPA_ACIBC
Sequence: MAQAKKSVDIKNIRNFSIIAHIDHGKSTLADRFIQMCGGLQDREMQAQVLDSMELERERGITIKAASVTLYYTHPNGQEYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQSVANCYTAIEQGLEVLPILNKIDLPQAEPERVIHEIEEIIGIEATNAPTCSAKTGLGVEGVLETLVDVIPAPTGDREAPLQALIIDSWFDNYLGVVSLVRIKDGRIRKGDKMLVKSTGQTHIVTSVGVFNPKHTETGVLEAGEVGFVIAGIKDIFGAPVGDTITLSTTPEVASLPGFKKVKPQVYAGLFPIDASDFEPFREALQKLQINDSALFFEPESSDALGFGFRCGFLGMLHMEIVQERLEREYDLDLISSAPTVVYEAVTKKGDTIYIDSPSKMPDGSVVEDLREPIAECHILVPQEYLGNVMTLCIERRGVQKDMKFLGNQVSITFEIPMAEVVMDFFDKLKSCSRGFASLDYNFIRFESSSLVKVDVLINGEKVDALAMICHRNDARHRGIALVEKMKDLIPRQMFDVAIQAAIGAQIIARSTVKAMRKNVLAKCYGGDVSRKKKLLAKQKEGKKRMKQVGSVEIPQEAFLAVLKVER
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SELU_ECOL6
Sequence: MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENMLAAEMLKTDAHQDLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAGSGGMG
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: CNIH1_MOUSE
Sequence: MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS
What is the function of this protein?
Involved in the selective transport and maturation of TGF-alpha family proteins.
What are the official names of this protein?
Protein cornichon homolog 1, CNIH-1, Cornichon family AMPA receptor auxiliary protein 1, Protein cornichon homolog.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane. Note=Located primarily in the ER; may cycle between the ER and the Golgi apparatus.
Protein: HIS8_YEAST
Sequence: MVFDLKRIVRPKIYNLEPYRCARDDFTEGILLDANENAHGPTPVELSKTNLHRYPDPHQLEFKTAMTKYRNKTSSYANDPEVKPLTADNLCLGVGSDESIDAIIRACCVPGKEKILVLPPTYSMYSVCANINDIEVVQCPLTVSDGSFQMDTEAVLTILKNDSLIKLMFVTSPGNPTGAKIKTSLIEKVLQNWDNGLVVVDEAYVDFCGGSTAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKAPYNISSLASEYALKAVQDSNLKKMEATSKIINEEKMRLLKELTALDYVDDQYVGGLDANFLLIRINGGDNVLAKKLYYQLATQSGVVVRFRGNELGCSGCLRITVGTHEENTHLIKYFKETLYKLANE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: HEMH_ACIB3
Sequence: MSFEQKPKVTVILANLGTPDEATVPAVRRFLKQFLSDPRVIEIPKFIWWIILNLFVLPFRPKRVAHAYASVWSTDSPMREIVFEQTQRVQAYLERENKQFDLTVLPAMTYGNPGIDAVLEKLATNPQEHVILLPLFPQYSATSTAPLYDAFAKWIPTQRNLPGLTIIKDYYQHPMFIQALAESVLAYQEQHGKPEKLLMSFHGIPQPYADKGDPYADRCRITAKLVAEALHLKDDEWAISFQSRFGKQEWVKPYTDQLLQDWAKQGVKSVQVLSPAFSADCLETLEELAIQNAELFQQAGGGSYAYIPALNSDQAHIDLLAGLVQANLDALTHTLAHR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF2_HUMAN
Sequence: MWRSCLRLRDGGRRLLNRPAGGPSASMSPGPTIPSPARAYAPPTERKRFYQNVSITQGEGGFEINLDHRKLKTPQAKLFTVPSEALAIAVATEWDSQQDTIKYYTMHLTTLCNTSLDNPTQRNKDQLIRAAVKFLDTDTICYRVEEPETLVELQRNEWDPIIEWAEKRYGVEISSSTSIMGPSIPAKTREVLVSHLASYNTWALQGIEFVAAQLKSMVLTLGLIDLRLTVEQAVLLSRLEEEYQIQKWGNIEWAHDYELQELRARTAAGTLFIHLCSESTTVKHKLLKE
What is the function of this protein?
May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase).
What are the official names of this protein?
ATP synthase mitochondrial F1 complex assembly factor 2, ATP12 homolog.
What is the protein family that this protein belongs to?
Belongs to the ATP12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PG050_MONPV
Sequence: MSKILTFVKNKIIDLINNDHQIKYSRVMMIEESDSLLPVDEVHVNHGFDCVEMIDENISNENIEQYKTESFFTIN
What are the official names of this protein?
Protein OPG050, Protein F6.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG050 family.
Protein: RL29_PROMT
Sequence: MSKTTTKDLRNLSDSEMSDKIQNLRKELFDLRFKQATRQLAKTHRFKEARTELAQLLTVSNERSRSNTSS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: YCIB_BURCH
Sequence: MKFLFDLFPIILFFVAFKVWGIFTATAVAIVATLAQVAWVAFRHRKVDTMLWVSLGVIVVFGGATLVLHDEKFIQWKPTVLYWLFAIGLLAARYAFGKNLIEKMMGKQLTLPVPVWDKLNVAWALFFAVLGVANLYVVHNFTESQWVNFKLFGTTGAMVVFIILQSLWLTKYLKDE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YB085_YEAST
Sequence: MSSALYKQSTNFTHSTGSFLQSAPVELTTVSGYQEFLKKQEKKNYEIQTVLSEDKSHGYVLKDGEVIANIIGEAKDYLLDLAGQA
What are the official names of this protein?
Uncharacterized protein YBR085C-A.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.