PharMolix/UniProtQA huggingface dataset:
Protein: CATK_RABIT
Sequence: MWGLKVLLLPVVSFALHPEEILDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSRSHSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENYGCGGGYMTNAFQYVQRNRGIDSEDAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDENCSSDNVNHAVLAVGYGIQKGNKHWIIKNSWGESWGNKGYILMARNKNNACGIANLASFPKM
What is the function of this protein?
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling.  Displays potent endoprotease activity against fibrinogen at acid pH.  May play an important role in extracellular matrix degradation.  Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
What are the official names of this protein?
Cathepsin K, Protein OC-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Secreted. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells.
Protein: BLMH_MOUSE
Sequence: MNNAGLNSEKVSALIQKLNSDPQFVLAQNVGTTHDLLDICLRRATVQGAQHVFQHVVPQEGKPVTNQKSSGRCWIFSCLNVMRLPFMKKFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPESHTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISSTQDAMMEEIFRVVCICLGNPPETFTWEYRDKDKNYHKIGPITPLQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSLKNMNKAERLAFGESLMTHAMTFTAVSEKDNQEGTFVKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVLPAWDPMGALAE
What is the function of this protein?
The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
What are the official names of this protein?
Bleomycin hydrolase, BH, BLM hydrolase, BMH.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule. Note=Co-localizes with NUDT12 in the cytoplasmic granules.
Protein: VF475_ASFK5
Sequence: MDQEESHVISIFETFGAYFINIFYNFLYKNALYKKHSIVMEYQYQVKGYILGVKQNKKLYEKMLDSFYKYFCNITQINSKTLSFSNFVSTIVDSFLPKEYSQSISLEKKDSILELLLCDYISNLGTFITTEKMLPFIVKNRKENYHRITKEMQDYSLTFLLKKRMELYNKFLRKQAYVEPKTELEETYTRLSSYNRSLLYQIEELTSEKKSLLAELSTLRKKYEKRQSEYRRLVQLLYQQIQRSSSSKNSYPLTKFIETLPSEHFSNEDYQKEAPRDQKQVETELLKQQEELLASQELTSKSPSNYPVPQSRTIVSKPSDNYPVPQSRSSKIDFDNSLQNQELNVKNGFSGKTILELNQDNPEIEEDILEFNQDNPEIEEDILEFNQDNPEIEEDILKFNQDNPEIEEDILKLNQDNPEIEEEVILEKENHKEDEPIVQNPFLENFWKPEQKTFNQSGLFEESSDFSNDWSGGDVTLNFS
What are the official names of this protein?
Uncharacterized protein B475L, pB475L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B475L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: NUDK_ECOLC
Sequence: MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDRGNGATILLYNTKKKTVVLIRQFRVATWVNGNESGQLIESCAGLLDNDEPEVCIRKEAIEETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDNQRANAGGGVEDEDIEVLELPFSQALEMIKTGEIRDGKTVLLLNYLQTSHLMD
What is the function of this protein?
Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.
What are the official names of this protein?
GDP-mannose pyrophosphatase, GDP-mannose hydrolase, GDPMK.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudK subfamily.
Protein: ESRP1_XENLA
Sequence: MTAVSPDYLVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKVGELHEVTVRPDHLELTEECKEITQIETDDLYVAPQLEQALQQFNQSVGNELNIGVGTSFCICTDGQLHVRQVLHPEASKKNILLPECFYSFFDLRKEFMKCCPGSSDINELDVHAMASFLGFEKKNTHYRYGASEVDDMGDIIVTLISEPYNYKFSDPERVNYKFESGTCSKLEMIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVLAFFGQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPVLPQPFIPPVNVRDCIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFPAQAAVIPTEAAALYQPSLLLNPRSLQPSAAAYYPAGAQLFMNYTAYYPSPPGSPSSLGFFPASAGVSTMPPHNTGAMVRMQGLAYNSGVKDILNFFQGYQYSPEDGLLPVNDQARALLTHPKEWVCI
What is the function of this protein?
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms.  Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of fgfr2.  Acts by directly binding specific sequences in mRNAs.  Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of fgfr2 (By similarity).
What are the official names of this protein?
Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A.
What is the protein family that this protein belongs to?
Belongs to the ESRP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOB_PSEP1
Sequence: MQYNLTRIDPDAPNEQYPVGERETVTDQLLEDQVHKNIFMGKLEDVLRGAVNWGRKNSLWPYNFGLSCCYVEMTTAFTAPHDIARFGAEVIRASPRQADFMVIAGTCFVKMAPIIQRLYEQMLEPKWVISMGSCANSGGMYDIYSVVQGVDKFLPVDVYVPGCPPRPEAFLQGLMLLQESIGQERRPLSWVVGDQGIYRAEMPAQKDLRREQRIAVTNLRSPDEV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL6_BRUA4
Sequence: MSRIGKKPVPVPAGVTASVDGQIVKAKGAKGELSFVVHDEVLVKMEDGAVSVDPRDQSKEARSKWGMSRTMISNIFVGVKDGFEKKLEISGVGYRAAMQGKNLQLSLGFSHEVVYDVPAGITVAVPKPTEIVVTGIDKQQVGQVAAEIREYRGPEPYKGKGVKYAGEKIVRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SYR_BURCM
Sequence: MLPAHKQTLEALLADSVTQVAHALKGADAAFVAPAITLERPKVAAHGDVACNVAMQLAKPLGTNPRQLAEKIVAALTAQPAAQGLVDAADIAGPGFINLRLTAAAKQAVIAAVFEQGRAFGTSDREKGKQVLLEFVSANPTGPLHVGHGRQAALGDVLANVIASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNRETVAAKDGEPVTGAGDIDDLDAIRKFAVAYLRHEQDMDLQAFGVKFDQYYLESSLYSEGRVEKTVDALVKAGMTYEQDGALWLRTTDEGDDKDRVMRKSDGTYTYFVPDVAYHVTKWERGFTQVINIQGSDHHGTIARVRAGLQGLHVGIPKGYPDYVLHKMVTVMRDGQEVKLSKRAGSYVTVRDLIEWSGGAAPGQEAAPDLIDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARICSVLNELKSRYNVDVAQLPGADLSQLTSAQAVSLMQKLAEYPDMLTHAAKELAPHAVAFYLRDLAGEFHSFYNAERVLVDDEAPRNARAALLAATRQVLENGLAVLGVSAPAKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMS4_PHYTS
Sequence: ALWKDILKNAGKAALNEINQIVQ
What is the function of this protein?
Antimicrobial peptide, active against the Gram-positive bacterium S. aureus, and the Gram-negative bacteria E. coli and P. aeruginosa.  Has hemolytic activity (5% hemolysis at 128 ug/ml).
What are the official names of this protein?
Dermaseptin-4, DStar 04.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_MAIZE
Sequence: MSLSTLSHPAAAAAGSGKSLFPAGPAAQSVHFPKARLPVPAAVSAATAAVHAEDRVSSLTQVSGVLGSQWGDEGKGKLVDVLAPRFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILHEGTLCVVGNGAVIHVPGFFGEIDGLESNGVRCGGRILVSDRAHLLFDLHQAVDGLREAELENSFIGTTKRGIGPCYSSKVTRNGLRVCDLRHMDTFGDKLDILFKDAASRFQGFQYSKSLLKEEVERYKKFADRLEPFIADTVHVLNESIKQKKKILVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRAIGDLIGVVKAYTSRVGSGPFPTELFGEEGDRLRKAGMEFGTTTGRPRRCGWLDIVALKHSCQINGFSSLNLTKLDVLSGLSEIKVGVSYTQTDGQKLQSFPGDLDTLEQVQVNYEVLPGWQSDISSVRRYDELPQAARLYVERIEELVGVPVHYIGVGPGRDALIYK
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, chloroplastic, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECR_PSEA8
Sequence: MSFSPLIRQLIESLRILPGVGQKSAQRMALMLLERDRSGGLKLAQALTAAMEGVGHCRQCRTLSEEELCPQCADPRRDDSLLCVVEGPLDVFAVEQTGYRGRYFVLKGHLSPLDGLGPEAIGIPELEARIRDGAFSEVILATNPTVEGEATAHYIAQLLAGRGLTLSRIAHGVPLGGELELVDGGTLAHALAGRRPIS
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HUB1_YEAST
Sequence: MIEVVVNDRLGKKVRVKCLAEDSVGDFKKVLSLQIGTQPNKIVLQKGGSVLKDHISLEDYEVHDQTNLELYYL
What is the function of this protein?
Forms conjugate with SPH1 and HBT1.  Involved in morphogenesis.
What are the official names of this protein?
Ubiquitin-like modifier HUB1.
Protein: NUOI2_MYCPA
Sequence: MAKFLDAVAGFGVTFASMFKKHVTEEYPEKPGPVAPRYHGRHQLNRYPDGLEKCIGCELCAWACPADAIYVEGADNTEELRYSPGERYGRVYQINYLRCIGCGLCVEACPTRALTMTNDYEMADDNRADLIYEKDRLLAPLLPEMTAPPHPRAPGATDKDYYLGNVTAHGLREAQRAGEPR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 2, NADH dehydrogenase I subunit I 2, NDH-1 subunit I 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KAD_LEPBA
Sequence: MKRLIFMGPPGAGKGTQADIIKEKYNIPQISTGDILRAAVKNGTAMGIEAKKYMDAGDLVPDAVVIGIIRDRLVEADCANGFILDGFPRTVEQAKALSEILKELHMELDSVVNLDVPDEELVKRLLGRAIKEGRSDDNEETIKNRLHTYNTKTLPLIDFYKATGILRQINGLGSMEEITNTILKSI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_METNO
Sequence: MARKPDPGRRIVADNRKARFNYEITDTVEAGIALTGTEVKSLRGGKATIGEAYAGPSGDEFFLFNAYIPEYLEANRFNHETKRPRRLLLHRRQINKFLGATQREGYTVIPLKIYFNERGRAKVELGLGRGKKLHDKRETAKERDWQRDRARLLRDKG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RS14_CLAMS
Sequence: MAKKSKIARNEQRKVIVERYAAKRLELKKALVDPNGTDESREAARAGIQRLPRDASPIRVRNRDGIDGRPRGNLSKFGISRVRFRDMAHRGELPGITKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: JZ35B_CHIGU
Sequence: MQVSVLITLAVLGVMFVWTSAAELEERGSDQPAWLKSLERIFQSEERDCRALYGGCTKDEDCCKHLACRRTLPTYCAWDLTFP
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U20-theraphotoxin-Cg1a 2, U20-TRTX-Cg1a, Jingzhaotoxin-35.2, JZTX-35.2, Peptide F3-18.97.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 40 (Jztx-35) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YDEM_BACSU
Sequence: MKLDEFTIGQVFKTKSLKVSKDDIMRFAGEFDPQYMHVDEEKASKGRFNGIIASGIQTLAISFKLWIEEGFYGDDIIAGTEMNHMTFIKPVYPDDELFTIVEVLDKQPKRNELGILTVLLSTYNQKEVKVFEGELSVLIKR
What are the official names of this protein?
Uncharacterized protein YdeM.
Protein: HYPA_GEODF
Sequence: MHELSIARSVVDICTENAGGRRVCSVTIEIGALSGVATESIRFCFDACTRGTLLENALLLIEHVPASGRCRQCNSEFPVKACYDPCPACGGVGMDLITGEELRVKGLTVV
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: PA2A_AIPLA
Sequence: MYPAHLLVLLAVCVSLLGASDIPPLPLNLYQFDNMIQCANKGKRATWHYMDYGCYCGSGGSGTPVDALDRCCKAHDDCYGVAEDNGCYPKWTLYSWQCTENVPTCNSESGCQKSVCACDATAAKCFAEAPYNNKNYNINTSNCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXC_LEGPH
Sequence: MIKQRTPKKVIQATGVGLHSGEKVLLTLRPAPVNTGIVFRRVDLSPVVEIPASYEYVGDTMLCTTLHHGKVKIATVEHLLSALAGLGIDNAYIDVNAPEIPIMDGSAAPFVFLIQSAGIREQNAAKRYIRILKPIRVEENGKYVQFLPHKGYKITFTIGFEHPVFNDRPQTVSFDFSGTSYVKEVCRARTFGFLSDYEKLRECDLAKGGSLDNAIVVDDYRVLNEDGLRFESEFVTHKVLDAIGDLYLLGSSLIGAFEGYKSGHELNNRLLRELMVRQDAWEYTYFDTENYLPAVHPEYYPVEA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: Y2372_ARATH
Sequence: MKMPPPFSASKTQYLFHDESSENSKKSLVSTTLSLSSCENPNKRKMNSDEVLNISCIPRDYKLTQVERKIARMRNLSYQEKAEDEWYGVSTELTLFKDPWIIKKVFHFASVLDMAPNSVSNTHCLLDTESPENAEESLVSLDLCFYDKTWPHDPNVAYNKPTSEEAINLAWMRTMSKRARKEEEKYYVSTELTLLTVADPWTLKMAMTKSSIGNLYRLVLKASFVDIHILRYLPLDDQMMVKEDSGLAVEVYDHDTDSVHNLALKKWAKSSSFVLVSGWRKCFVDRRGLQVGDVIGMYWDRSESKLHFCVLSRSETMDSAPLPPSP
What are the official names of this protein?
B3 domain-containing protein At2g33720.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1148_MYCTU
Sequence: MRSDTREEISAALDAYHASLSRVLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACEEELGGTLRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTATAAAQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRPDHLHGLATQLMDWLHPDGNFSDQERARKRGITMGKQEFDGMSRISGLLTPELRATIEAVLAKLAAPGACNPDDQTPLVDDTPDADAVRRDTRSQAQRNHDAFLAALRGLLASGELGQHKGLPVTIVVSTTLKELEAATGKGVTGGGSRVPMSDLIRMASHANHYLALFDGAKPLALYHTKRLASPAQRIMLYAKDRGCSRPGCDAPAYHSEVHHVTPWTTTHRTDINDLTLACGPDNRLVEKGWKTRKNAHGDTEWLPPPHLDHGQPRINRYHHPAKILCEQDDDEPH
What are the official names of this protein?
Uncharacterized protein Rv1148c.
What is the protein family that this protein belongs to?
Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
Protein: RL14_HAHCH
Sequence: MIQTQTVLDVADNSGARRVMCIKVLGGSHRRYASIGDVIKVSVKEAIPRGKVKKGQVLKAVVVRTRKGVRRQDGSLIRFDGNAAVLLNNQEQPIGTRIFGPVTRELRGEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CYSG_CHRVO
Sequence: MEFFPIFLKLRHQRCLLVGGGEVALRKARLLLAAGASLQVVAPELAPELADLAERGELEHLPGRYAPALLDGMRLAVAATDDAEVNRAVAADAEARGILVNVVDDAEASRYISPAIIDRSPLMVAVASGGSVPVLARSIRARLESLIPAGYGRLARFGSSFRDAVKARFPDVDARRRFWETVLEGPLADAVMNGDEAAARAEMEKRIAAGGADRAGAVYLVGAGPGNPDLLTFRALRLMQQADVVLYDKLVAPELLELVRRDAERVYVGKARANHALPQDDINQLLVDLARQGKRVLRLKGGDPFTFGRGGEEIATLAEHGIAFEVVPGITSASGAAAYAGIPLTHRDYAQSVTFVTGHKQDGSIDLDWQALTRPQQTVVVYMGVSTAAELCQAFVDNGRAASTPAAAVEWATTERQRTVCGTLAALPGLMASHGIASPALIIVGEVVELADKLSWYRRSENSAVTIQED
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: MET3_ASHGO
Sequence: MLSPHGGILQDLVARDAEKKDRLLHEAQGLPQWNLTARQLCDIELILNGGFSPLTGFLGKEDYESVVQNSRLTSGLLWTIPITLDVDEEFAKSVNLGERIALLQDDDIFVAIITVSDIYTPDKKVEADKVFRGDEEHPAIQYLNETAGDIYLGGELEAIQLPAHYDYLNLRKSPAALRADFATQQWDRVVAFQTRNPMHRAHRELTIRAAKEHNAKVLLHPVVGLTKPGDIDYHTRIKVYKEIVKRYPEGIAQLALLPLAMRMAGDREAVWHAIIRKNYGATHFIVGRDHAGPGTNSKGDDFYGPYDAQVLVESYKNELGIEVVPFKLITYLPDKDIYLPVDEIDGSVKTLTISGTELRKRLREGTDIPDWFTYPEIVEILRQYNPPRYRQGFVIVVNHENPKRIANALLSTFLQVGGGRQYKIFDHQGQPQLLELIPDFVKSGTGLIVTSPLPSSVDAHNIYELNTYPSAHIKVSATEPVTEIVQKTVFFLEDNKFFQF
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VLF1_NPVHZ
Sequence: MNNHPATLRNESSFNYWKSRIQNHDKFDEIFELTTDRQRCTPDEVKNNSLWSQYMFCKPFAPTTLKSYKSRFIKLIYCLIDDEYLNNYYDTHTLNKEFNSIVQQQPLIKPEELCRRMLELRSVTKETLQLTINFYTNTMNLPEYKIPKQVMLPRDKEIKNIKNNEKNIVLREIINTILDCIEKKIKHLSSEFVHDRGLIRGAIVFCIMLGTGMRINRSRHLSVDDLNTLIKRGKLRQAIGLKRKKHRTSNSLNSIKQKPLELAREIYIKNPNILNISKNTSTPFKDFKRLLKEANVEMDRPRSNMIRHYLSSNLYNNGMPLQKVARLMNHESSASTRHYLNKYDVGVDESDDNDEDDDDDENDDRIIDENPSGANISNYDINNSSSGNSSSNNTSGNDFNNNISSGDDADLLSFN
What is the function of this protein?
Involved in very late gene activation.
What are the official names of this protein?
Very late expression factor 1.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: TLC3A_MOUSE
Sequence: MLLTLASGALFFPGLFALSIWALHRLRPGWTEDDCLTVGTRLVSSVQAVLATWAGLTVIISCKNVVSDRHWLATEYVWFLIPYMIYDFYAMYCCERCRTKSQKLTRTTIIRNFLIENRLMVTHHTVILLFLVPISQKLRGDLGDFFVGCIFTAELSTPFVSLARIMIQLKQQHTLLYKVNGILTVTTFLFCRILLFPFMYWSYGQQKGLSLLQVPFNIPLHCNMANAVLISPQLYWFSLLCKKAARLFDTAKAKKDG
What are the official names of this protein?
TLC domain-containing protein 3A, Protein FAM57A.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL31_HAHCH
Sequence: MKQGIHPEYKEITATCSCGNIIKTKSTLCENIHIDVCSSCHPFYTGKQKVLDTGGRIDRFKKRFGGRMGRSS
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: IPO5_MOUSE
Sequence: MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGRSKITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNMGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTNLNNMQRQLALEVIVTLSETAAAMLRKHTSLIAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPQRPWPDRQWGLCIFDDIVEHCSPASFKYAEYFISPMLQYVCDNSPEVRQAAAYGLGVMAQFGGDNYRPFCTDALPLLVRVIQAPEAKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA
What is the function of this protein?
Functions in nuclear protein import as nuclear transport receptor.  Serves as receptor for nuclear localization signals (NLS) in cargo substrates.  Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.  Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5.  In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones.  Binds to CPEB3 and mediates its nuclear import following neuronal stimulation (PubMed:22730302).
What are the official names of this protein?
Importin-5, Imp5, Importin subunit beta-3, Karyopherin beta-3, Ran-binding protein 5, RanBP5.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.