PharMolix/UniProtQA huggingface dataset:
Protein: RL36_DEIGD
Sequence: MKVRSSVKRMCDNCKVIRRHGRVLVICTNVKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RS12_ERWAM
Sequence: MATVNQLVRKPRVRKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKNAKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NUOI_HELP2
Sequence: MAKQEYKQLPKRSEVHSTTEQFKDTVKTSLGLDLFKGLGLTIKEFFSPSVTIHYPMEQLPLSPRYRAVHHLQRLLDSGSERCIGCGLCEKICTSNCIRIITHKGEDNRKKIDSYTINLGRCIYCGLCAEVCPELAIVMGNRFENASTQRSQYGSKSEFLTSEQDAKNCSHAEFLGFGAVSPNYNERMQATPLDYVQELSKEESKEETPTSPESHKGDENV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GBGT1_CANLF
Sequence: MRCRRLALGLGFSLLSGIALWSLWIYMETWLPFSYVPYYLPCPEIFNMKLQYKGEKPFQPVTRSPHPQPKLLEQRPTELLTLTPWLAPIVSEGTFNPELLQHIYQPLNLTIGLTVFAVGKYTRFVQHFLESAEQFFMQGYQVYYYIFTNDPAGIPRVPLGPGRLLSIIPIQRHSRWEEISTRRMETISRHIAQRAHREVDYLFCVDVDMVFRNPWGPETLGDLVAAIHPGYYAVPRQQFPYERRHISTAFVAENEGDFYYGGAVFGGRVAKVYEFTTGCHMAILADKANGIMAAWQEESHLNRRFISHKPSKVLSPEYLWDDRKPQPPSLKLIRFSTLDKATSWLRS
What is the function of this protein?
Catalyzes the formation of Forssman glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to GalNAcb-1,3Gala-1,4Galb-1,4GlcCer (Gb4Cer) (PubMed:8855242, PubMed:10506200).  Forssman glycolipid (also called Forssman antigen; FG) probably serves for adherence of some pathogens such as E. coli uropathogenic strains (PubMed:10506200).
What are the official names of this protein?
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, Forssman glycolipid synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: YP7_AGRT4
Sequence: MNFADTPLASLDLDWACEEFIKTYGASPQLETGEVIQTNNGLLYLYGKGSLSQRIHDTHLKFKEKEELSFTTIKPAEMKAQQSDLTYYVAIFQSNYFLCVSNPEKGFLRCHNRPFLYPIVAHGSMS
What are the official names of this protein?
Uncharacterized protein 7, Open reading frame 3.
Protein: ABAH3_ORYSI
Sequence: MAASFVIVIVISFFISLAFMCYVHYTSRQRRKLHGYGHEKAVRLPPGSMGWPYIGETLQLYSQDPNVFFASKQKRYGEIFKTHILGCPCVMLASPEAARFVLVTQAHLFKPTYPRSKERMIGPSALFFNQGDYHLRLRKLVQGPLGPDALRALVPDVEAAVRSTLASWDGNVSSTFHAMKRLSFDVGIVTIFGGRLDERRKAELRQNYAIVEKGYNSFPNSFPGTLYYKAIQARRRLHGVLSDIMRERRARGEPGSDLLGCLMQSRAGDDGALLTDEQVADNIIGVLFAAQDTTASVLTWIVKYLHDHPKLLEAVRAEQAAIRAANDGGRLPLTWAQTRSMALTHKVILESLRMASIISFTFREAVADVEYKGFLIPKGWKVMPLFRNIHHNPDYFQDPQKFDPSRFKVSPRPNTFMPFGNGVHACPGNELAKLEMLVLIHHLVTGYRWEIVGSSDEVEYSPFPVPKHGLLAKLWRDDTVSVETDGCQNGDNDDNGVAMV
What is the function of this protein?
Involved in the oxidative degradation of abscisic acid.
What are the official names of this protein?
Abscisic acid 8'-hydroxylase 3, ABA 8'-hydroxylase 3, Cytochrome P450 707A7, OsABA8ox3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HIKES_MOUSE
Sequence: MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYENINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGVPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNIVRTPSVAQIGISVELLDSLAQQTPVGSAAVSSVDSFTQFTQKMLDNFYNFASSFALSQAQMTPNPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
What is the function of this protein?
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus.  HSP70 proteins import is required to protect cells from heat shock damages.  Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity).  May also be indirectly required for organization and/or function of the secretory apparatus in Club cells in lung.
What are the official names of this protein?
Protein Hikeshi, Lethal gene on chromosome 7 Rinchik 6 protein.
What is the protein family that this protein belongs to?
Belongs to the OPI10 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Nucleus.
Protein: ACKA_DESVV
Sequence: MNVLVINSGSSSIKYQLIDMEREVPLCSGLVERIGEPMGKLTHKIRPDAEGEEKLTFEQPFTNHVEGMKRVVELITDADKGVIKDKSEIGAIGHRVLLGGEEIKQSVRIDDWAKGVIRDYIPLGPLHNPANLAGIEVAEELFPGLPNVGVFDTEFHQSMPAKAYLYPLPIELYEELKIRRYGFHGTSHRYITKRTAQYLGKPLDELNIITCHLGNGCSMAAVKNGKCVDTTMGITPLEGLMMGTRCGDIDPAIVPFLMEKKNLSPAEADTLMNKQSGLKGVCGMNDMRDLHAARENGNERAQLAFEMFTYRIKKYIGAYYAVLGRVDAVVFTAGIGENDDFVRAEVCAGLDSLGIAVDPARNAVRNGQPRHISPDGSRVAVLVVPTNEELEIAQATLDVLKG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_STRZT
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDRVKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVAAERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y713_CHLMU
Sequence: MTTYPVPQNPLLLRVLRLMDAFSKSDDERDFYVDRVEGFILYIDLDKDQEDLDKVYQELEENADRYCLIPKLTFYEIKKIMETFVNEKIYDIDTKEKFLEIVQSKNAREQFLEFLYDHETEQEKWQQFYVERSRIRIIEWLRNNKFQFVFEEDLDFSKHVLEQLKVHLFDAKVSKELTQARQLLVNKSKVYYSNEALNPRPKRGRPPKQSAKVEAETTVSSDIYTKVPSAARRFLFLPEITSASSLTFSEKFDTEEEFLAHLRGGGRLEDQLNLAKFSERFDSLRELSAKLGYDGDGDASDFFGEEYDDDDDDDDDVKPKKAAKRGRKKARS
What are the official names of this protein?
UPF0158 protein TC_0713.
What is the protein family that this protein belongs to?
Belongs to the UPF0158 family.
Protein: DTD_SYNWW
Sequence: MRAVVQRVSFSEVRVEGKLRGRIKQGLMVLLGIKKGDSKAEGDYLLEKIVNLRIFPDEEGKMNRSLLDIEGEILLVSQFTLYGDARKGRRPSFSAAELPELAEALFDYCVDGLRQRGVQVETGTFGAEMLLSIENDGPCTILLDSEKLF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_SPOFR
Sequence: MVAAKKQKKTIESINSRLALVMKSGKYCLGYKQTLKTLRQGKAKLVIIAKNAPPLRKSEIEYYALLAKTGVHHYSGNNIELGTACGKYYRVCTLAITDPGDSDIITTLPESQV
What are the official names of this protein?
60S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: GUAA_NEIG2
Sequence: MTQDKILILDFGSQVTRLIARRVREAHVYCELHSFDMPLDEIKAFNPKGIILSGGPNSVYESDYQADTGIFDLGIPVLGICYGMQFMAHHLGGEVQPGNQREFGYAQVKTIDSGLTRGIQDDAPNTLDVWMSHGDKVSKLPDGFAVIGDTPSCPIAMMENTEKQFYGIQFHPEVTHTKQGRALLNRFVLDICGAQPGWTMPNYIEEAVAKIREQVGSDEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGKMVMDMFARNLGVKVIHVDAEGQFMAKLAGVTDPEKKRKIIGAEFIEVFDAEEKKLTNAKWLAQGTIYPDVIESAGAKTKKAHAIKSHHNVGGLPENMKLKLLEPLRDLFKDEVRELGVALGLPREMVYRHPFPGPGLGVRILGEVKKEYADLLRQADDIFIQELRNTTDENGTSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVITSDFMTAHWAELPYSLLGRVSNRIINEVKGINRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GSA_PERMH
Sequence: MKMERSLNLFEEAQRYLVGGVNSPVRAFKSVGMEPLFIQKGKGSRVWDVDGNEYIDYVLSWGPLILGHANDQIVNAIKQVANYGTSFGAPTELEIEMAKAVVDAVPSIEMVRFVNSGTEATMSAIRLARGYTGKKKIVKFEGCYHGHVDSLLVSAGSGVATLSIPGTPGIPEEFANLTIVLPYNNIDAVEETFKKHGDDIACVIIEPVAGNMGVVAPSKEYHQRLREITKEYGALLIWDEVMTGFRLAYGGAQELYGIEPDLTTLGKVIGGGLPVGAYGGKREIMEYVAPVGPVYQAGTLSGNPLAMAGGLRQLQILKEKNPYPDLDRKGKKLEEGLRYLSEKYGIPATVNRVGSMITAFFTDKEVVDFETAKSSDLDRFAKFFRLMLEKGVYLAPSQFEAAFLSTAHSDEDIDETLNKAEDCFKQLL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAHO_BOVIN
Sequence: MAAAHRCLFLLLLSTCVALLLQPPLGALGAPLEPEYPGDNATPEQMAQYAAELRRYINMLTRPRYGKRDKEGTLDFLECGSPHSAVPRYGKRDKEGTLDFLECGSPHSAVPRWVFSLSCVPRCLGQENGGV
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide prohormone.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: TIPRL_MOUSE
Sequence: MMIHGFQSSHQDFSFGPWKLTASKTHIMKSADVEKLADELHMPSLPEMMFGDNVLRIQHGSGFGIEFNATDALRCVNNYQGMLKVACAEEWQESRTEGEHSKEVIKPYDWTYTTDYKGTLLGESLKLKVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADKTYMLREYTSRESKIANLMHVPPSLFTEPNEISQYLPIKEAVCEKLVFPERIDPNPVDSQSTPSE
What is the function of this protein?
May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A).  Inhibits catalytic activity of the PP2A(D) core complex in vitro.  The PP2A(C):TIPRL complex does not show phosphatase activity.  Acts as negative regulator of serine/threonine-protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex; the function is proposed to implicate it in DNA damage response by promoting H2AX phosphorylated on Ser-140 (gamma-H2AX).  May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair (By similarity).
What are the official names of this protein?
TIP41-like protein.
What is the protein family that this protein belongs to?
Belongs to the TIP41 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHA2_MOUSE
Sequence: MAPSHPAFQFWIHLYLWCLLLMPAVLAQQGSHTHAEDRLFKHLFGGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAEFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERTVDLKDYWESGEWAIINATGTYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHNMPNWVRVALLGRVPRWLMMNRPLPPMELHGSPGLKLSPTYHWLETNMDAEEREETEEEEEEEEDENICMCAGLPDSSMGVLYGHGSLHLRAMGPEAKTPSQASEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFLPPFLAGMI
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-2/CHRNA2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: YABA_STAS1
Sequence: MNRSDIFEKLANLEANINQINSDMGNLKKLTVEVIEENVALQIENENLKTLIDKEEKSKAVENGKKLPKKQPLRSKDNLAMLYKEGFHICNGELFGKHRKGDDCLFCLEVLSE
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: NANO1_DANRE
Sequence: MDFLNHNYLSARASYDYTFNFWNDYLGLSTLVTKNSKHSVPQNPNSITESLKATLGLDDSPPCPCVMGEGDSGGHLDSCCCPPPASISILDLKERFSILSPFQNQNQGSLLSSSQEREIGIGGGFAGFDLFGVERKMRKPAARNKQEPKICVFCRNNGAPEEVYGSHVLKTPDGRVVCPILRAYTCPLCSANGDNAHTIKYCPLSKDQPAQRVLKGGRAVGGKRVKIF
What is the function of this protein?
May act as a translational repressor which regulates translation of specific mRNAs.
What are the official names of this protein?
Nanos homolog 1.
What is the protein family that this protein belongs to?
Belongs to the nanos family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region.
Protein: DSG4_HUMAN
Sequence: MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.  Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity).
What are the official names of this protein?
Desmoglein-4, Cadherin family member 13.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: ENO_CLOTE
Sequence: MKNYIEIIDVSARQVLDSRSNPTVEVDVILEDGTTGRAAVPSGASTGIFEAVELRDGDKSVYNGKGVLKAIENVNTIIAEELVGMNVLDQIAIDKTMIELDGTDNKGKLGANAMLGVSLACAKAAAEYLGLSLYQYIGGVNAKVLPVPMMNIINGGEHADNNVDLQEFMIMPAGASSFSEALRMCSEVYHSLKSLLKAKGYDTGVGDEGGFAPNLNSNEEAIQVIVEAIEKAGYKPGVEIFIALDPASSEIFEDGKYNLKGEGKVLTPQEMVDYYANLVAKYPIISIEDGMAEEDWEGWRLITERLGTKIQLVGDDLFVTNTDRLTMGIERGVANSILIKLNQIGTLTETLNAIEMAERAGYTAVVSHRSGETEDTTIADLVVAVNAGQIKTGAPARSERVAKYNQLLRIEDELGEMGEYRGLKAFYNIKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MMRN2_MOUSE
Sequence: MIPTLLLGFGVYLSWGLLGSWAQDPGTKFSHLNRPGMPEGWRLGAEDTSRDPIRRNWCPYQKSRLVTFVAACKTEKFLVHSQQPCPQGAPDCQGVRVMYRVAQKPVYQVQQKVLISVDWRCCPGFQGPDCQDHNPTANPEPTEPSGKLQETWDSMDGFELGHPVPEFNEIKVPQEQQENLLQNLQNDAQSVEDGFPGSWEAPPSNLTDEMTEANLTEFEFPGRTSEHLLQPHIDAFLKAHFSPIWKNFNDSLHSLSQAIRNLSLDVEANHQAIKMIQEGTVARADFQELGAKFEAKVQQNSQRLGQLWQDVEDQLHAQRRSVHHALSDVQAEVSTKLKQLVKAQELPGANGSLVMASAAAAARPEPESLQARLGQLQRNLSALHMVTSQREEELQSTLKNMDSVLKQHAEEIKELYSESDETFDQISKVERQVEELLVNHTGLRELRVILMEKSLIMEENKEEIERQLLELNLTLQHLHAGHADLIKYVKDCNCQRVNSDVDVAPEGHRDVMHTLEETQVSLDEQHQLDGSSLQALQSTVDAMSSAMDAYRGEGERARAERARIRSQLRALDHAVEALKTAANGTRKEIRLLHGSFTALLEDALRHQAVLAALFGEEMIDEMSEEAPRPLPLDYEQIRLALQDAASGLQEQAIGWEDLATRVEALEKAAGGFVEQHPQLAEGLEPSHDSGREEEAMTLAELEQEIRRLSSDVKQIGQCCEASWAASLNSSLEDLHSMLLDTQHGLRQHRQLFHNLFQNFQGLVASNISLDLGKLQAMLSKKDKKQPRGPGESRKRDKKQVVMSTDAHAKGLELWETGSPVAFYAGSSEGATALQMVKFNTTSINVGSSYFPEHGYFRAPKRGVYLFAVSITFGPGPGMGQLVFEGHHRVPVYSTEQRGGSTATTFAMVELQKGERAWFELIQGSATKGSQPGTAFGGFLMFKT
What is the function of this protein?
Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it down-regulates KDR activation by binding VEGFA.
What are the official names of this protein?
Multimerin-2.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: TILS_SCHPO
Sequence: MDTIKLKEFYNSLVSIRRRVGHRRLGIAVSGGVDSMLLSWFMKESQIMFGWPNQFIAFVVDHRIRKNSTEEALQTIWNLNRMLIPNVYLNINWGNDDVHSLTNLETIAREHRYQVLTRACITHNIRHICTAHHANDQAETIFMRLLRRKPGTWGGLCAMKPVSQIPESDSICGASNIELLRPLLPYYKNQILNTAKQHGIAWEEDPTNADINLTPRNAIRRFLNQHAALTVEATKLATAFQSLQVNIDNKVDEILKDNIVSYHQPSGTLSLCFSKNELKKHSNLTKEELLLRCLTLTTSCRQIKRSSVVSLCNSVFDGKKLTIAKCLLTSSSIKDDTKLQLQISRQPFSKAELKKKTITINPDRYVLWDHRFWIKYSCKNTQTTLILRPLLSKDLNSLKGFLSKEEFLKFCIQVPGHIRFTIPVLSEENDKLVGIPTFGFNFRSDIISNCLHKFKL
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity).
What are the official names of this protein?
Probable tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDA_PSEFL
Sequence: MDAFNYRGGELFAEGVALSAIAERFGTPTYVYSRAHIEAQYRTFADALEGMPHLVCFAVKANSNLGVLNVLARLGAGFDIVSGGELERVLAAGGSADKIVFSGVGKTREDMRRALEVGVHCFNIESTDELGSRLQIVAAELGVRAPISLRVNPDVDAGTHPYISTGLKENKFGIAIADAEDVYVRAAQLPNLEVLGVDCHIGSQLTTLEPFIDALDRLLALVDRLGDCGIYLRHIDLGGGVGVRYRDEEPPLVADYIKAVRERLDGRDLALMFEPGRYIVANAGVLLTQVEYLKHTEHKDFAIVDAAMNDLIRPALYQAWMDVTAVRPRDTAARSYDIVGPICETGDFLAKGRELALEEGDLLAVHSAGAYGFVMSSNYNTRGRCAEVLVDGDQAFEVRRRETVAELFAGESLLPE
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: ETT1_KLULA
Sequence: MAKRALGLGKSKKQKKQKVAVPEEQSSEGTVPAPSAANQIEIALDENEDADDELVQLKGLWETFLKDKDNQLLLNGVVHECDRLLRLQDNDSTIKLSDLFHSIYAQALAELTVFLPEETDDEEKKYERMNEFFDAALERYRLGAEKYPETPLLSLTQTKIILQRIPLQYISQLSPLDQNDEKYKLYDLLESAKSSYTLSSNQHQLAYDVLLSFYDLLDIIETFEDKEELEDGLDSDDEGEELVEVVLHENHPLTKIKKNMNQNYEWLKENLLNLFNDISSSFCNKVGPDIDKDHPTVVLFKSIARTLGQLYLKLAEEPSKTFAELMYDSDDEEQTDKEALEKAKNAQSKAIPLVEYAIRYLQEAKVEDEPQTWVDVAEAIIDLGNLYDYESKEQEDSYKRAEEILLKANKATHGKYQVILDNLLNKD
What is the function of this protein?
Required for correct translation termination and probably involved in regulation of hypoxic gene expression.
What are the official names of this protein?
Enhancer of translation termination 1.
What is the protein family that this protein belongs to?
Belongs to the ETT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBFL_PROM9
Sequence: MDFRVLLVISPIIFAWIFTVFWLGKWDVFRLTPFGLPKRGVAPFENYQVWGDSAVVPNTGRPSEGYPVFTVRTAAVNALGIPTVFFLGAILAMQFKSY
What is the function of this protein?
Unknown.  Resembles PsbF, one of the subunits of the photosystem II reaction center.  However, it encodes asparagine rather than histidine at the site PsbF uses to bind heme.
What are the official names of this protein?
PsbF-like protein.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYD_MANSM
Sequence: MMRSHYCGGLNRENIGQEVTLSGWVHRRRDLGGLIFIDMRDREGIVQVCFDPKYQQALTRAASLRNEFCIQIKGEVIARPDNQINKNMATGEVEVLAKELSVYNAADVLPLDFNQNNTEEQRLKYRYLDLRRPEMAQRLKTRAKITSFVRRFMDDNGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFLTAPEVREIMEKMIHGLWLNTINVDLGKFPVMTWTEAMQRFGSDKPDLRNPLEITDVADIVKDVDFKVFSGPANDPNGRVAVIRVPNGASVTRKQIDEYTQFVGIYGAKGLAWLKVNDVNAGLEGVQSPIAKFLTEEKIKAIFDRTSAQTGDILFFGADKWQTATDALGALRLKLGRDLALTQLDQWAPLWVIDFPMFERDEEGNLAAMHHPFTSPKDFSPEQLEADPTGAVANAYDMVINGYEVGGGSVRIFDPKMQQTVFRILGIDEQQQREKFGFLLDALKFGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPQALEELSISVVKTDKE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.