PharMolix/UniProtQA huggingface dataset:
Protein: CCD61_HUMAN
Sequence: MDQPAGLQVDYVFRGVEHAVRVMVSGQVLELEVEDRMTADQWRGEFDAGFIEDLTHKTGNFKQFNIFCHMLESALTQSSESVTLDLLTYTDLESLRNRKMGGRPGSLAPRSAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLQGLDGQNTRDTRENEIWHLREQVSRLASEKRELEAQLGRSREEALAGRAARQEAEALRGLVRGLELELRQERGLGHRVAGRRGQDCRRLAKELEEAKASERSLRARLKTLTSELALYKRGRRTPPVQPPPTREDRASSSRERSASRGRGAARSSSRESGRGSRGRGRPARPSPSPTGGRALRFDPTAFVKAKERKQREIQMKQQQRNRLGSGGSGDGPSVSWSRQTQPPAALTGRGDAPNRSRNRSSSVDSFRSRCSSASSCSDLEDFSESLSRGGHRRRGKPPSPTPWSGSNMKSPPVERSHHQKSLANSGGWVPIKEYSSEHQAADMAEIDARLKALQEYMNRLDMRS
What is the function of this protein?
Microtubule-binding centrosomal protein required for centriole cohesion, independently of the centrosome-associated protein/CEP250 and rootletin/CROCC linker (PubMed:31789463).  In interphase, required for anchoring microtubule at the mother centriole subdistal appendages and for centrosome positioning (PubMed:31789463).  During mitosis, may be involved in spindle assembly and chromatin alignment by regulating the organization of spindle microtubules into a symmetrical structure (PubMed:30354798).  Has been proposed to play a role in CEP170 recruitment to centrosomes (PubMed:30354798).  However, this function could not be confirmed (PubMed:31789463).  Plays a non-essential role in ciliogenesis (PubMed:31789463, PubMed:32375023).
What are the official names of this protein?
Centrosomal protein CCDC61, Coiled-coil domain-containing protein 61, VFL3 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC61 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Localization at the centriolar satellite is dependent on intact microtubule network (PubMed:30354798). Localizes at the centriole subdistal appendages and proximal ends (PubMed:31789463). Localized to centrosomal/satellite-like structures with the onset of centrosome separation in early G2 (PubMed:30354798).
Protein: Y5169_ARATH
Sequence: MEDRHRYLFFIFAIIHYVQAQQGFISLDCGLPSNEPPYIEPVTGLVFSSDADHIPSGISGRIQKNLEAVHIKPYLFLRYFPDGLRNCYTLDVLQNRRYMIKAVFVYGNYDGYNDYPSFDLYLGPNKWVRVDLEGKVNGSVEEIIHIPSSNSLQICLVKTGNSLPFISALELRLLRNDTYVVQDVSLKHLFRRYYRQSDRLIRYPDDVYDRVWSPFFLPEWTQITTSLDVNNSNNYEPPKAALTSAATPGDNGTRLTIIWTLDNPDEQIHLYVHFAELEPVGENTDEALRTLFTRTFYFVVNGKISYDESITPLDLAVSTVETVVNKCDGGNCSLQLVRSEASPGVRVPLVNAMEAFTAIKFPHSETNPDDVISIKVIQATYELSRVDWQGDPCLPQQFLWTGLNCSYMNMSTSPRIISLDLSSHKLTGKIVPDIQNLTQLQKLDLSNNKLTGGVPEFLANMKSLLFINLSNNNLVGSIPQALLDRKNLKLEFEGNPKLCATGPCNSSSGNKETTVIAPVAAAIAIFIAVLVLIIVFIKKRPSSIRALHPSRANLSLENKKRRITYSEILLMTNNFERVIGEGGFGVVYHGYLNDSEQVAVKVLSPSSSQGYKEFKAEVELLLRVHHINLVSLVGYCDEQAHLALIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVETALGLEYLHSGCKPLMVHRDVKSMNILLDEHFQAKLADFGLSRSFSVGEESHVSTGVVGTPGYLDPEYYRTYRLTEKSDVYSFGIVLLEIITNQPVLEQANENRHIAERVRTMLTRSDISTIVDPNLIGEYDSGSVRKALKLAMSCVDPSPVARPDMSHVVQELKQCIKSENLRLRTGLNQVIDSKSS
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At5g16900.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TRPE_RHIME
Sequence: MAAVILEDGAESYTTKGGIVVTRRRREASYSDAIAGYVDRLDERRGAVFSSNYEYPGRYTRWDTAVVDPPLAISSFGRSLWIEAYNERGEVLLALIAEDLKSVADITLGSLAARRLDLTINEPDRVFTEEERSKMPTVFTVLRAVTNLFHSEEDSNLGLYGAFGYDLAFQFDAIELKLSRPDDQRDMVLFLPDEILVVDHYAAKAWIDRYDFARENLSTEGKAADIAPEPFRSVDSIPPHGDHRPGEYAELVVKAKESFRRGDLFEVVPGQKFYERCESRPSEISNRLKAINPSPYSFFINLGNQEYLVGASPEMFVRVSGRRIETCPISGTIKRGDDPIADSEQILKLLNSKKDESELTMCSDVDRNDKSRVCVPGSVKVIGRRQIEMYSRLIHTVDHIEGRLRDDMDAFDGFLSHAWAVTVTGAPKLWAMRFIESHEKSPRAWYGGAIGMVGFNGDMNTGLTLRTIRIKDGIAEVRAGATLLYDSNPEEEEAETELKASAMIAAIRDAKSANSAKSARDVAAVGAGVSILLVDHEDSFVHTLANYFRQTGASVTTVRTPVAEEIFDRVKPDLVVLSPGPGTPKDFDCKATIKKARARDLPIFGVCLGLQALAEAYGGDLRQLAIPMHGKPSRIRVLEPGIVFSGLGKEVTVGRYHSIFADPSNLPREFVITAESEDGTIMGIEHSKEPVAAVQFHPESIMTLGGDAGMRMIENVVAHLAKRAKTKAA
What are the official names of this protein?
Anthranilate synthase.
Protein: Y4FA_SINFN
Sequence: MGWVDRLLSRFKIRTKVMLLVLPFILSISAVGVTGMLASGLLQSRMAISNDVAASLRGFKDVYAAMIGFLDQTTEENRALVFSKLDEQRAALDAAGARLTPKAEGWAELESASAALSAINGRMDDLWALHADEARLEAGIKEALGVISTSQADLLTAATAFDKSISTQEDDAKEKLRDAQRILSATSFVVALRDAFAARKDDGEGYRAIAAAMGDLKIHQKLLPIALPKKSKPLGKAFSANVRALSALVDDKARPPENIEKILDVFAELKALKEPLEAAATAKMQHVSTTFEELDASVAKAGLVMQDTRHLTDAIYLTRIALAEFMLDRSAEKQSTLAMHLAQCRNALFALSSTAGDLGFAGEQSTKLATSFDRIEQSAVELVGATGKRTQQFQAAADEIDHIGEQISLFADLQRSAAGRQSQDANRLSIGAMVLGVIIALVSGAALVLTLKGPIGEITQTMRNLAGGLLDTAVANRNRADEIGEMARALDVFKTNAKARIALEQRSEQERVAAHAERERNEAEKLRRDQEIAFAVDALADGLDAMAKGRLTSTIETPFAPALDKLRTDFNAAVAGLRQTLLDIRTTSSVIQGSGRQMAEGAKALSGRTEQQAASLEETAASVDEIVATIRRAGDQAANADNTVSKAKQDADRSTVVVGNATAAMGRIEAASSHIGHIIEVIDDIAFQINLLALNAGIEAARAGEAGKGFAVVAQEVRELAQRSAGAAREIAALIGNSTAEVAKGAGLVSETGAALLDISKHILEISTQIEAIALSSREQASSIAEVNVAITRLDQLTQSNAAMAEETQAASWTLSGEADYLMQLVDRFDLGENSGSASETMKAA
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.  Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity).
What are the official names of this protein?
Probable chemoreceptor y4fA, Methyl-accepting chemotaxis protein.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PA2BW_PROFL
Sequence: MRTLWIMAVLLVGVEGHLLQFRKMIKKMTGKEPIVSYAFYGCYCGKGGRGKPKDATDRCCFVHDCCYEKVTGCDPKWDYYTYSSENGDIVCGGDNPCTKEVCECDKAAAICFRDNLKTYKKRYMTFPDIFCTDPTEKC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 PL-X', svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CARB_MYCLE
Sequence: MPRRTDLNHVLVIGSGPIVIGQACEFDYAGTQACRVLRAEGLQVSLVNSNPATIMTDPEFADHTYVEPITPAFVERVIVQQAERGNRIDALLATLGGQTALNTAVALYENGVLERYGVELIGADFEAIQRGEDRQRFKDLVAKVGGESARSKVCFTMDEVRETVEDLGLPVVVRPSFTMGGLGSGMAHSDEEVGRMAGAGLVASPSANVLIEESVYGWKEFELELMRDGHDSVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDWEYQRMRDLGIAILREVGVDTGGCNIQFAINPHDGRLIVIEMNPRVSRSSALASKATGFPIAKIAVKLAVGYTLDEILNDITKETPACFEPALDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFVEALGKVMRSLETGRFGFWTAPDPQGDVDQVLLRLKTPTEGRLYDVELALRLGASTEKVAQVSGIDPWFVAQIGELVKLRDELVAAPVLDAELLRRAKHNGLSDRQITALRPELLGEDGVRSLRKRLGIHPVYKTVDTCAAEFEAKTPYHYSSYELDPAAETEVVPQTEKPKVLILGSGPNRIGQGIEFDYSCVHAAITLSHNGFETVMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVFYAEEQSAAGGAGVAGVIVQLGGQTPLGLAQRLADAGVPIVGTSPEAIDLAEDRGAFGDVLTAAGLPAPKYGTATTFAQARRIAAEIGYPVLVRPSYVLGGRGMEIVYDEETLKDYITRATALSHEHPVLVDRFLEDAVEIDVDALCDGTEVYIGGVMEHIEEAGIHSGDSACALPPVTLGRSDLEKVRQATEAIARGIGVVGLLNVQYALKEDVLYVLEANPRASRTVPFVSKATAIPLAKACARIMLGSSISQLRFEGMLAASGDGGNVASHAPIAVKEAVLPFNRLRRADGAAIDSLLGPEMKSTGEVMGIDHDFGRAFAKSQTAAYGSLPTQGTVFVSVANRDKRLLVFPVKRLADLGFHVIATEGTAEMLRRKGIPCDEVRKHFEPPKAGRPALSAVDAIRAGDVDMVINTPYGNSGPRIDGYEIRSAAVSVNIPCVTTVQGASAAVQGIEAGIRGDIGVRSLQELHSAIGAGIAADNEVQ
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RL15_MYCTO
Sequence: MTLKLHDLRPARGSKIARTRVGRGDGSKGKTAGRGTKGTRARKQVPVTFEGGQMPIHMRLPKLKGFRNRFRTEYEIVNVGDINRLFPQGGAVGVDDLVAKGAVRKNALVKVLGDGKLTAKVDVSAHKFSGSARAKITAAGGSATEL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SYE_PSEPF
Sequence: MTTVRTRIAPSPTGDPHVGTAYIALFNYCFAKQHGGEFILRIEDTDQLRSTRESEQQIFDALRWLGIDWSEGPDVGGPHGPYRQSERGDIYQKYCQQLVDMGHAFPCFCTAEELDQMRAEQMARGETPRYDGRALLLSKEEVARRLAAGEPHVIRMKVPSEGVCVVPDMLRGDVEIPWDRMDMQVLMKTDGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLILLYEYFGWEQPELCYMPLLRNPDKSKLSKRKNPTSVTFYERMGFMPEAMLNYLGRMGWSMPDEREKFSLQEMVDNFDLKRVSLGGPIFDIEKLSWLNGQWLRDLPVEEFAARVQKWAFNSEYMMKIAPHVQGRVETFSQVAPLAGFFFAGGVNPDAKLFESKKLSGDQVRQLMQLILWKLESLRQWEKDSITATIQAVVESLELKLRDAMPLMFAAITGQASSVSVLDAMEILGPDLTRFRLRQAIDLLGGVSKKENKEWEKLLGAIA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPD_METMA
Sequence: MLKIGIIGCGFIGGQICRAIDSGEIDAELYALCDSSESKAFGLAKSLNTCKPAYMKIEELISSVDLVVESASQNAVRFIVPQALKAGCSVMVLSVGALADKELRETLFGLAKKHNCKLYFPSGAVVGIDGINSAHAAGISSVTLTTRKPPSGLMGAPYVVEHGIELEKLEKETILFEGTASEAVKAFPANVNVAATISLAGIGFERTMVRVIADPSLSRNIHEINVEGEFGKFCTKVENLPSPENPKTSYLAALSAISTLKKILNPVQIGT
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: APOE_LIPVE
Sequence: MKVLWVALVITLLAGCQAEVEPEPEPEVQLGQEWPGWQDSQPWEQALGRFWDYLRWVQTLSDQVQEELLSTQVIQELTVLMDETMKEVKAYREELEGQLAPIAQETQARVSKELQAAQARLASDMEDVRSRLAQYRSEVQAMMGQTTDELRGRLASHLRKLRKRLLRDAEDLQKRLAVYRAGALEGSERSVSAIRERLGPLVEQGRARAATVGTLASQTLRERAEAWHQKLRGRVEEMGTQARDHLEEMREQLEEVRAKVEEQGSQMRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQLAMATSSTSAPSENH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: LGT_STRS2
Sequence: MNTIEKRLNMDPIAIKLGPLEIRWYAICILLGLILGVYLATKEGPRKKIRQDDILDFILIAFPLSILGARIYYVAFSWSEYKDNILSIFAIWNGGIAIYGGLITGAIVLYFFTQYRFINTLDFLDIVAPSVMIAQAIGRWGNFFNQEAYGKAVESLNYLPAFIRDQMYIDGAYRQPTFLFESLWNLLGFGLVCVLRRRPKFLKQGEITAFYLVWYGCGRLLIEGLRTDSLMFLGIRVSQWLSGVLILVGIIMVVLRRRKSSIPFYQP
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1400_ARATH
Sequence: MTLKGALSVKFDVKCPADKFFSAFVEDTNRPFEKNGKTEIEAVDLVKKTMTIQMSGSEIQKYFKTLKGSIAVTPIGVGDGSHVVWTFHFEKVHKDIDDPHSIIDESVKYFKKLDEAILNFKE
What are the official names of this protein?
Uncharacterized protein At1g24000.
Protein: DENR_ASPFU
Sequence: MSEVAQNSPAEVQAKKVVYCGVCTLPPEYCEFGGTAKKCEEWLKDNHAELYQRLYSEEALSSNLSELSVSVRERAAKDAAKKEAKAAAAEARDAERKAAAKVQIKRVERNKRKHVTVITGLEVHGLENKKVAKELGKKFATGSSVTKSPAGVEEITVQGDVSEDVKEWLLELYGKEIPESNIELVEDKKKKTSG
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGP_NITMS
Sequence: MKKRTFAVDIDGTITENGGGRIHLDALESLRRLVNMGHDVIFVTGRSSVEGFLLSVFGGTTKVSVGENGGCITLDSNDHILLGNLEECKNALNILKNNMENVEEKYVFPRMTEVVLQRTFDLDQARKILSENNIDVVLSDSQYAYHINSPGIDKGTGFTEIMKKFSISRDDVIAIGDSATDVPLFKVAKTSVALGNASDDVKSEATMTVSAHAGDGVLEALDKLAPILSEI
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: RS19_STAHJ
Sequence: MARSIKKGPFVDDHLMKKVEAQDGSEKKQVIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHAADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PLSX_NITSB
Sequence: MVRIAVDAMGGDFGPYPIIEGTILALKENPNFKAILVGHKEKIQTLIPHKYNNRIEIVHAEDVIRMDEAATEALKRKESSIYKAVELVRTGEAEGVVSAGHSGATMSLATLRIGRLKNVSRPAIATLMPTYKNKKSLVLDVGANVDCKPEHLFEFGVMGEAYATAIMNVDKPKVGLLSNGEEETKGNELTKNAFTMLKSLPTFIGNVEGNNIFDGSVDVIVCDGFTGNIVLKTSEGVADAISKLMKANIKKTPIRMAGALMMKKVFRSLKKEIDYSEYGGAPLIGVKGCTIISHGKSTPKAIKNAIYQAITYIKSDINTKIEKRLEEVTPKG
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: 3608L_ASFP4
Sequence: MLSLQTLAKKVVACNYLSSDYDYTLQRFGLWWDLGPIHLCNNCKQIFSYKHLQCFSEDDLCLEAALVKAVKSDNLELIRLFVDWGANPEYGLIRVPAVHLKRLCTELGGLTPVTEPRLLEILKEVAKLKSCAGVLLGYDMFCHNPLLETVTRTTLDTVTYTCSNIPLTGDTAHLLLTKFWFALALRHNFTKAIHYFYKRHKNHLYWRVACSLYFNNIFDIHELCREKEICISPNLMMKFACLQKKNYAAIYYCYRLGASLDYGMNLSIYNNNTLNMFFCIDLGATDFDRAQHIAHKAYMYNLSNIFLVKQLFSRDVTLALDVTEPQEIYDRLKSYTSKNLKRAEEYLTAHPEIIVID
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-8L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: RL6_KLEP3
Sequence: MSRVAKAPVVVPAGVDVKVNGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYVDGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGDVVNLALGFSHPVEHKLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TYSY_STAA8
Sequence: MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLSKGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYKGPDMTDFGHRALSDPEFNEQYKEQMKQFKQRILEDDTFAKQFGDLGNVYGKQWRDWVDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINSDKSIFDINYEDLEIVDYESHPAIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_PECCP
Sequence: MAADAFLLIFGLLLTVLIVAQPLGSGLARLIEGETGTLLQKFEAGTARLFALDTTEMRWQQYAAAILTLNLIGIVVLFVLLMAQGVLPLNPENMPGLSWHLALNTAISFVTNTNWQAYSGENTLSYLSQMVGLTVQNFLAAASGIAVAFALIRAFSRRCVDTLGNAWLDLFRITLYVLLPLSLLLALFFVSQGVLQNLLPYQHLTTLDGAAQTLPMGPVASQEAIKLLGTNGGGFFGANSAHPFENPTALSNIVQMLAILLIPTALCFAFGKAVSDNRQGHALLWAMGLIFIVAAAVVMKMEVIGNPHLLALGADSAANLEGKETRFGVLTSSLYAVVTTATSTGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGRSPEYLGKKIEVYEMKMTALAILIPPALVLLGTALALSTEAGRSGILNPGAHGFSEVLYAVSSAANNNGSAFAGLSVNTPFYNVLLAVAMLLGRFAVMVPVLAIAGSLVVKKRQPESKGSLSTRSPLFIGMLIAIVLLIGALTFIPALALGPVAEHLQFGLTH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCAL1_ARATH
Sequence: MATSIARLSRRGVTSNLIRRCFAAEAALARKTELPKPQFTVSPSTDRVKWDYRGQRQIIPLGQWLPKVAVDAYVAPNVVLAGQVTVWDGSSVWNGAVLRGDLNKITVGFCSNVQERCVVHAAWSSPTGLPAATIIDRYVTVGAYSLLRSCTIEPECIIGQHSILMEGSLVETRSILEAGSVVPPGRRIPSGELWGGNPARFIRTLTNEETLEIPKLAVAINHLSGDYFSEFLPYSTVYLEVEKFKKSLGIAV
What is the function of this protein?
Involved in complex I assembly in mitochondria and respiration.
What are the official names of this protein?
Gamma carbonic anhydrase-like 1, mitochondrial, AtCAL1, GAMMA CAL1.
What is the protein family that this protein belongs to?
Belongs to the gamma-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein; Matrix side. Note=Probably integral to the membrane.
Protein: RL16_PROMA
Sequence: MLSPKRTKFRKQQRGRMRGVATRGNKIAFGQFALQAQECGWITSRQIEASRRAMTRYVKRGGQIWIRIFPDKPVTMRPAETRMGSGKGNPEFWVAVVKPGRILFEMGGEEITEEIAKEAMRLAQYKLPIKTKFLALAEGEKPTQVGKAPPKSSFLPSDETETAAAQAGTEASSASSVTPLES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TUSC_YERPP
Sequence: MARKRIAFIFTQGPHGSSAGREGLDALLATSALSEDIGVFFISDGVLQLLPQQQPEKILARNYIATFGVLPLYDVENCYLCERSLQQRGLSKMADWILDVTVLSPADLRRELGTYDVVLTF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFW_KLEPN
Sequence: MMEWFYQIPGVDELRSAESFFQFFAVPYQPELLGRCSLPVLATFHRKLRAEVPLQNRLEDNDRAPWLLARRLLAESYQQQFQESGT
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: SWC5_ASHGO
Sequence: MIAPTEPTEGNSRASVLEFDEEGYVESEDEDFDPSKPADDDKEEELSDKSDGDYQEADEEAEKYDYSHIESSEGGLVSTRNARRLQHEREQREKYEHFEMQGVSSRAGELWAQLQEESQARLHDTSSVMHAGGEAGKDRMQEEQIMIERAYWFAGEMVREKKMVLKSSAEAQEYLNSLKFKPKELVPSTMQEMDGGSKLRRPLKRPPILEQIIAGALKPKLTTLEKSKLDWATYVDKEGINEELQLFNKDGYLAKQDFLRKVDGIQNEQYKELRRQELQKNGAQGM
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
SWR1-complex protein 5.
What is the protein family that this protein belongs to?
Belongs to the SWC5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPF_BACC3
Sequence: MSQFSFTKMHGLGNSYIYVNMFEEQIPEEDLALVAEKVSNINTGIGADGMILICPSDVAPVKMRMFNNDGSEGKSCGNGLRCVAKYAYEHKLVEDTVFTIETLAGIVTAEVTVEEGKVTLAKIDMGAPRLTRAEIPMLGEGETPFIRENFLYNNHRYAFTAVSMGNPHAVIFVDDVEQAPLTTLGPVLETHEMFPERVNVEFIEILNEEEMNFRVWERGSGVTQACGTGACAAVVASILNGKMERGKEITVHLAGGDLMIAWTEEGNVLMKGPAEVICHGVYEYKIEA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_SOLM1
Sequence: MLEKLGFIALAGAAGTLARYWLSGLVYDVLGRDFPWGTAVVNILGCFLFGLVWEAGAERMLLRTEARAVLLTGFMGAFTTFSTFIFESGGLLEDHRYLALLANLGFQTILGFAALFAGLALGRLI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.