PharMolix/UniProtQA huggingface dataset:
Protein: TRYT_DROER
Sequence: MHGLVVLLVCLAVGSAFAGTIGVSNADPFEREGRIVGGEDTTIRAHPYQVSLQNKKGSHFCGGSLINEDTVVTAAHCLVGKKIAKVFVRLGSTLYNEGGIVVAVRALTYNADYSSKTMENDVGILKLAEKVKETDDIRYIELATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQAVYVNIVDWKTCASDEYKYGEVIYDTMVCAYEKKKDACQGDSGGPLAIGNTLVGIVSWGYACASNLLPGVYSDVPALRKWILNASQTL
What are the official names of this protein?
Trypsin theta.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RS10_PASMU
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: F120B_MOUSE
Sequence: MGVRGLQGFVGSTCPHICTIVNIHELAERHRNKYPGCTPTIVVDAMCCLRYWYTAESWVCGGQWREYYCALRNFVAAFTSAGIKLIFFFDGMVEPGKRDEWVKRRLKNNREISKIFHYIKSKRDQPGRNMFFIPSGLAIFTRFALKTLGQETFCSLQEADYEVASYGLQHNCLGILGEDTDYLIYDTCPYFSIGDLCLESLQTIMLCREKLCESLGLRVADLPLLACLLGNDITPESMFESFRYKCLSSYASVKENAGKKGNIILAVSDYISKVLHLYQGEKKIEEMLPLGPNKALFYKGVTSYLLPGQKSPWLVQKPKGMITDKQQMVSLNPESKQEVPMCIDPEFKQEVPVCTNPESMQEVPMCMDPEPNQEASMCTDPESKQEVPMCTDSESKPEVSQYTNPESKQKLPSGIDTEFNLEALMCTHPEFKQEDVMDMEPEIKQVTMVSESEILKVARMHHVHSESYLVYNILSSGEIECSNTLEDELDQALPSQAFIYRPVRQRVYALLLGDWKDGASTGPVVKEWFVYPGNSLKHPDLVRPLQMTVQGGTPSLEVLWLSQEPAVQAQRLDTLLACFNLSSSREELQAVESPLRALCCLLIYLFVQVDTLSLEDLHAFIAQALCLQGKSTSQLMHLQLDYINSRAVQLGSLLVRGLTTLVLVNSACGFPWTTSEFMPWNVFDGKLFHQKYLQSEKGYAVEVLLEQNRSWLTKFHNLKAVVCKACSKENRRIVGRTHWDSPYTGRQGRQGYSSYRTDSTHGHSGQSWRNQGSGGRQHERNHWRRY
What is the function of this protein?
Functions as a transactivator of PPARG and ESR1.  Functions in adipogenesis through PPARG activation.
What are the official names of this protein?
Constitutive coactivator of peroxisome proliferator-activated receptor gamma, Constitutive coactivator of PPAR-gamma, Constitutive coactivator of PPARG, Protein FAM120B.
What is the protein family that this protein belongs to?
Belongs to the constitutive coactivator of PPAR-gamma family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL1_BORPD
Sequence: MAKLSKRAAAIAKKIDRTKLYPVSEALTLVKETATAKFDESIDVAVQLGIDPKKSDQLVRGSVVLPAGTGKSVRVAVFAQGDKAEAARAAGADIVGLDDLAERIKGGQIDFDVVIASPDTMRVVGALGQVLGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQYRTDKAGIIHATIGRASFGVEQLQTNLAALVDALQKARPAAAKGIYLRKLAVSSTMGGGARIEVASLSAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CH60_PETMO
Sequence: MAKMLKFNEDARRALERGVNTVADAVKITLGPKGRNVVLEKSWGSPTITNDGVSIAKEIELKDKFEALGAELVKEVASKTNDVAGDGTTTATVLAQAMIQEGLKNVAAGANPILMRNGIAKATDKAVEQIRNASRKLSSKEDIAHVASISANNEEIGNIIAEAMDKVGEDGVITVEDSKTLETYVEFTEGMQFDRGYISPYFVTNTEKMEAEMKEPYILITDRKISAVKSIVPILEKVAQAGKPLVIIAEDVEGEALSTLVLNKLRGTLESVAVKAPGFGDRRKEMLRDIAILTGGTVISEEIGLTLEDISINDLGQADLVRVAKEDTIIVGGKGEPTAIKERIAQIKAQIENTSSDYEKETLQERLAKLSGGVAVIKAGAATETELKEKKHRIEDALSATRAAVEEGIVAGGGVTLLRAKKAVEEFANTLSGDEKIGAQLVAKSLDAPVKQIIRNAGLEPAIIIEKIIEKDDSKYGYDVLKERYVNMFESGIIDPTKVTRSALQNAASIASMLLTTEVLVAEEPKEEKGPEMPATPDMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_ACIBY
Sequence: MSLSPKQEQLFKQASKHIPGGVNSPVRAFNGVGGTPVFIEKAKGAYLWDVDGKRYVDYVGSWGPMILGHAHPDIIKAVQTAAEDGLSFGAPTVHETTLADIICEIMPSIELVRMTNSGTEATMTAIRLARGYTGRDKIVKFEGCYHGHSDSLLVKAGSGLLTKGEGEPTSKGVPADFAKHTLTLPYNDIAALKECFAKFGHEIAGVIIEPVAGNMNMVKPIDGFLQAIRDVCDEYKSVFIIDEVMTGFRVALGGAQSVYNVKPDLTTLGKIIGAGLPVGAFGGKREIMECIAPLGGVYQAGTLSGNPLAMRAGIEMFKHLRQPDFYSKLSAQLEKLLAGLQAAADEAGIPFKTQQAGAMFGLYFTDQEDITSFDSMLACDIEAFKKFFHGMLKRGVNLAPSAFEAGFISSAHSDEDIEFTIQAAKETFAEMK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_CLOPS
Sequence: MSRELIRTVDAWNKVKIARDPNRPNTKFYINEIFDEFIELHGDRNFGDDKAIIGGIALLNNLSFTVVGICKGENTKENIKRNFGMPHPEGYRKALRLMKQAEKFKRPVICFVDTPGAFCGIGAEERGQGQAIAQNLVELIGLKVPLISIVIGEGGSGGALALAVADKVFMLEHSIYSVLSPEGFASILWKDSSRAEEAASVMKITAQDLKRFNIIDKIIKEPRGGAHKNPIKMAQNIKKTILEALGEMKGTDLDTLLNERYNKYRNIENNL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWNB_BACSU
Sequence: MKIGIIGASGKAGNEILKEAKKRGHEVTAIVRNASKVQEQDVAILEKDVFELTAEDIKPFDAVVNAFGAAPGQEHLHVEAGRALISILKDAKHTRLLVVGGAGSLFVDEAKTTRLMDTPEFPKEYLPTASNQGENLKDLQQTDSISWTFLSPAAFFDPAGKRTGSYQKGKDNVIVNAKGDSYISYADYAIAVLDELEHPEHKNERFTVVSEAE
What are the official names of this protein?
Uncharacterized protein YwnB.
Protein: MMS19_MOUSE
Sequence: MAAATGLEEAVAPMGALCGLVQDFVMGQQEGPADQVAADVKSGGYTVLQVVEALGSSLENAEPRTRARGAQLLSQVLLQCHSLLSEKEVVHLILFYENRLKDHHLVVPSVLQGLRALSMSVALPPGLAVSVLKAIFQEVHVQSLLQVDRHTVFSIITNFMRSREEELKGLGADFTFGFIQVMDGEKDPRNLLLAFRIVHDLISKDYSLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSCSVLRADAEDLLGSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACEHLTSNVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYEDRDERPLSSFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGAQPGLLSAEDLELAVGHLYRLTFLEEDSQSCRVAALEASGTLATLYPGAFSRHLLPKLAEELHKGESDVARADGPTKCSRHFRCLQALSAVSTHPSIVKETLPLLLQHLCQANKGNMVTESSEVVAVCQSLQQVAEKCQQDPESYWYFHKTAVPCLFALAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPDQFQPFQDGSSGQRRLVALLTAFVCSLPRNVEIPQLNRLMRELLKQSCGHSCPFSSTAATKCFAGLLNKQPPGQQLEEFLQLAVGTVEAGLASESSRDQAFTLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGCAAADGFSLLMSDCTDVLTRAGHADVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDSVVQLSTLSCLQPLLLEAPQIMSLHVDTLVTKFLNLSSSYSMAVRIAALQCMHALTRLPTSVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS
What is the function of this protein?
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity.  In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target Fe/S proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER), homologous recombination-mediated double-strand break DNA repair, DNA replication and RNA polymerase II (POL II) transcription.  As a CIA complex component and in collaboration with CIAO1 and CIAO2, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins.  As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD.  Together with CIAO2, facilitates the transfer of Fe-S clusters to the motor protein KIF4A, which ensures proper localization of KIF4A to mitotic machinery components to promote the progression of mitosis.  Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
What are the official names of this protein?
MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein.
What is the protein family that this protein belongs to?
Belongs to the MET18/MMS19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: ATPA_BRASO
Sequence: MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLETDNVGVVIFGADREIKEGQTVKRTRAIVDAPVGKGLLGRVVDALGNPIDGKGPIQFTERKRVDVKAPGIIPRKSVNEPMATGLKAIDALIPIGRGQRELIIGDRQTGKTAIALDTILNQKPLNAQPDEKIKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDPAPMQYLAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNETQGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKMEEQVCVIWAGTNGFLDGLPLNKVRAFEDGLLSLLRGKHADLLNTIRDTRDLSDDSAAKLKAAVEGFAKTFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ZN287_MOUSE
Sequence: MANSSLSQVLLMWKPGKIQKGPCSAEQQTLTSRLLRDTETCRRNFRNFPYPDVAGPRKALCQLRELCLKWLRPEVHSKEQILELLVLEQFLSILPGEVRTWVNSQYPESSEEVVALVEDLTQILEEEEAPQSSALPQDTPEDDPNHDPNPASQAGWLSDVVTKDLVTFNDVAVDITQEDWELMPPVQKELYKTVTLQNYWNMVSLGLTVYRPTVIPVLEEPWMVIKEIVEGPNPEWEPKAQAQCPAKHLPELKQDGTQTVKLEDSYDDDNDDSVESPPVCAFGMIHIDEEGFSVKSELSQEDPTEEYLSKCDIYRVTFEKHTNLGVQFDTQSDDKTALYNESKPPFSNASSGGAVRGKILPGDKPYSCNVCGKQFRKYPSLLAHRENHAKEKAYECEECGKEFKHLSSLIAHQRMHTGEKPYECHQCGKAFSQRAHLTIHQRIHTGEKPYKCEDCGKDFSQRAHLTIHQRTHTGEKPYKCLECSKTFSHSSSLINHQRVHTGEKPYICNECGKTFSQSTHLLQHQKIHTGKKPYKCNECWKVFSQSTYLIRHQRIHSGEKCYKCTACGKAFAHSSTLIQHQTTHTGEKSYICNVCGKAFSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEKPFKCNTCGKAYRQGANLTQHQRVHTGEKPYKCHHCGKAFIYSSSLNQHRRTHTGERPYKCSHCNKDFSQRTCLIQHQRIHTGEKPYGCRICGKAFTQSTNLIQHQRVHTGARHRN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 287, Zfp-287, Zinc finger protein SKAT-2.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URE3_LYSSC
Sequence: MKLSPVEQEKLLLHVAGELALKRKARGLKLNYPEAVALISSFIMEGARDGKTVAQLMSEAKHVLTAEDVMEGVGDMISDVQVECTFPDGTKLVTVHRPIQ
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_GRAFK
Sequence: MTSQELTEQILKKQSFLCVGLDTDLDKIPTYLLSEKDPVFSFNKAIIDATHQYCVAYKPNIAFYEAIGVDGWKALKKTIEYLHAEYPDLYTIADAKRGDIGNTSRMYAKAFFEDLGFDSITVAPYMGKDSVEPFLEFTNKHTILLALTSNEGAFDFQTLKTGDKELYKKVIETSKNWQNSENLMYVVGATKAEYLAEIRKIIPENFLLVPGVGAQGGSLEEVCKYGMTKNVGLLINSSRKIIYASDSSNFAEIAGAKAEAMQNQMASELEKL
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: GSA_ALCBS
Sequence: MPRKHSEQLFRQAQKHIPGGVNSPVRAFKSVGGTPVFFHSARGAHLFDEDDNKYIDYVGSWGPMILGHNHPHVVAAVQAAVEQGLSFGAPTATEVAMADKVCELVPSMDMVRMVNSGTEATMSAIRLARGYTGRNKIIKFEGCYHGHVDSLLVKAGSGAIAIPGSPGVPEAVTADTLVLDYNDAASVTQAFKEHGDDIAAVIVEPVAGNMNCVPATENFLQTLRQQCDDNGAVLIFDEVMSGFRVALGGAQGHYGITPDMTTLGKIVGGGMPVGAFGGKQAIMEHLAPLGPVYQAGTLSGNPVAMAAGLATLNLISEPGFHQALAEKTTRLLEGLTAAAHAEGVAFTTAQAGAMFGLFFTDQNRISSFTEVMACDSERFNRFFHAMLDQGIYLAPSAFEAGFVSAAHSNDDIDATITAARKAFGKI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OST5_YEAST
Sequence: MTYEQLYKEFHSSKSFQPFIHLDTQPKFAICGLIVTLAVLSSALFAVGSKSSYIKKLFFYTILSVIGSLFAGLTTVFASNSFGVYV
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5, Oligosaccharyl transferase subunit OST5, Oligosaccharyl transferase 9.5 kDa subunit, Oligosaccharyl transferase subunit zeta.
What is the protein family that this protein belongs to?
Belongs to the OST5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NSP3_ROTP5
Sequence: MLKMESTQQMVSSIINTSFEAAVVAATSTLELMGIQYDYNEIFTRVKSKFDYVMDDSGVKNNLLGKAATIDQALNGKFGSTIRNRNWMTDSKTVAKLDEDVNKLRMILSSKGIDQKMRVLNACFSVKRIPGKSSSVIKCTRLMKDKIERGEVEVDDSFVDEKMEIDTIDWKARYDQLEKRFESLKQRVNEKYNSWVQKSKERNENMYSLQNVISQQQNQIADLQQYCNKLEADLQSKISSLVSSVEWYLRSMELSDDVKTDIEQQLNSIDAINPINAIDDLESLIRNLIQDYDRTFLMLKGLVRQCNYECTYE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RSMB_PSEAE
Sequence: MNPRLAACQALAAVLAGRASLSGALPPQLDKVAPRDRGLTQELAFGAARWQPRLQALAARLLQKPFKAADTDIHALLLIGLYQLLYTRIPPHAAIGETVGCADKLKKGWAKGVLNAVLRRAQREGETLLAEVDRDPSARLGHPRWLLKALKQAWPEQLDALCAANNAHPPMTLRVNRRHGERDAYLAELAEAGIKARACDYSRDGIQLAAPRDVRELPGFAEGRVSVQDEAAQLAAEQLESAPGQRVLDACCAPGGKTCHLLETQPELAEVVAVDLEESRLVRVRENLQRLGLQASLVAADARATGEWWDGKPFQRILLDAPCSATGVIRRHPDIKLARKPEDIAALAHLQGELLDALWPTLEVGGVLLYATCSVMPAENSDSIAAFLARTPGARELDLPGPWGMKQPHGRQLLPQVEGHDGFYYAKLIKISAR
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHBP_SALDC
Sequence: MDTLTAIGRWLAKQHVVTWCVHHEGELWCANAFYLFDAQNVALYLLTDDKTRHAQMSGACAPVAGTVNGQPKTVARIRGVQFKGEIRRLEGQESDAARKAYLRRFPVARVLPAPVWEIRLDEIKFTDNTLGFGKKLHWLRDSRAQQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: MSRB_LEIXX
Sequence: MDAGKGEYQIAKSDEEWRRELTPEQYGVLRQAGTEQPWTGELLDESRAGVYACAACGAELFRSGTKFDSGCGWPSFYESVRPEAVELLEDTRLGITRTEVRCANCGSHLGHVFPDGFRTPTGDRYCMNSISLDFQPEDE
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RUVB_HERAR
Sequence: MSIQTDDFSEQRVIAATPASANEEAIERALRPKQLDEYVGQEKIRGQLEIFITAARQRREALDHTLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPLELTRIVTRSSSLLNAPIDEDGAFEIAKRSRGTPRIANRLLRRVRDYAEVKGNGDITKAMADAALVMLDVDPVGFDVMDRKLLEAVLFKFNGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRIATPVAYAHFGVTAPQTGPNGELWGGQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GATE_METKA
Sequence: MREEDLDWEEIGLRVGLEIHRQLDTSRKLFCRCTPELVEEVPKEPKVRRKLRPVQSEMGEFDPAALEEFKRDRTFYYLADGSFSCLVELDEEPPHEPCSEALDVAIKVTLLLGGSVVDEVHVMRKMVIDGSNTTGFQRTMLVGFGGEVPTSEGPVRISTVCLEEDAARKVKGRDQDLEVDYCLDRLGIPLIEVSTEPDIRTPEQAREAAERIGEAIKAVGGVKSGIGTVRQDVNVSIEGGAVQEIKGVQDLNLIPKVVKYEALRQANLLRIRDELRERGVSETDLIDCEPMDVTDVFEDTDSEVIRRELERGGVVYALLLPGFEGILGWELCPGRRFGTELADYARRRGVSGLFHSDELPKYGISEEEVEAVRQRLGAEDGDGFVLIAGPEDRVKSAMEAVKDRAIMALKGVPAETRRARKDGTTEYMRPRPGAARMYPETDIPPVVIDEDRVKELAEELPEKPWERKERLAEEYGLGEELVEQMFEHGVVDEFEEIVEETGVEPKVAAATLVNTIPRLEKDGYPVDNLTIDHVKEVLRLYAEGAIAKSGIEELLGALAADPDSDPEELAEELGIVMASEEEIEEVVEEAIRRYEDKIRERGMAVMGKIMGEVMEVLRGRADGKRVSELVRERIREISGE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: NADE_MYCBO
Sequence: MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEICEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGFATGEHTKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHPYSVGEKVYDVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEITPELIPTGEEELQSSEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses L-glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine-dependent NAD(+) synthetase, NAD(+) synthase [glutamine-hydrolyzing].
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD synthetase family.
Protein: MURE_CYTH3
Sequence: MQIKDLIYKVSLISVSGRTDVDVTAICFDSRKVEKGSMFIAVRGVSSDGHSFIADVIQKGATAVVCEELPEIESTADCTIIQVKDSAEALGMIASNFYDSPSSKLKLVGVTGTNGKTTTVTLLYRLFRKLGYKTGLLSTVENIIEDKVVQATHTTPDAISLNKLLADMVKAGCTHCFMEVSSHAAVQRRIAGLQFAGGLFSNITHDHLDYHKTFDEYIKAKKLFFDGLPNDSFALINSDDKRGRVMIQNTRAKTYTYSLLALADFKGKLISTTMQGLEMDVDGIQAWFRLIGNFNAYNLLAVYATAVLLGEDKEEVLMQLSTIEAANGRFEQQISATRITVIVDYAHTPDALKNVLETITELKGANKIITVVGCGGNRDAAKRPVMADIACQFSDHVVLTSDNPRNEEPQAILTEMEKGVRIVDKKKVLSVLDRKEAIKVACTLASTGDIILVAGKGHETYQEIKGVKYPFDDRLIIKELLDTLGK
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE6D_DROVI
Sequence: MGSDDLSAGDKIQKGFQINYMILRDADTGKVIWQENKDFSAPDVEHEARVPVKILDMRAVSREINFSTIEAMENFRLDQKVLFKGRIMEEWFFEMGFVGANTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNETLITKSVVRLYYI
What are the official names of this protein?
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y2196_RIPO1
Sequence: MILTINEVLTSSELNKLLDGLSRAPFVDGKTTAGWHAKLVKNTVQLDKNSQEWKKAENIVKTALDRNMLLKMAVLPKRIHSLLFSRYETGMSYGSHVDNGFMGGQEFWRSDVSFTLFLTSPDSYKGGELVIEMTEGERIYKLEAGSMIVYPSSFLHRVETVTDGVRLVVVGWIESLVRDPSEREFLFDLDTVRRSIFTKEGKSLEFDILSKTYANLLRKWGK
What are the official names of this protein?
PKHD-type hydroxylase PCC8801_2196.
Protein: Y0740_MYCTU
Sequence: MTGPPRSYTGRRDLIAEKLEPYFQISAMLPKNTRPTSETAEEFWDNSLWCSWGDRETGYTRTVTVSICQVADGEREAEGVRDMMRLECPAGLDLRTPNPEAYEITGQRPGEFVFVLGYLGHVRAIVGNCYIEIMPMGTRVELSKLADVALDIGRSVGCSAYENDFTLPDIPTQWRNQPLGWYTQGLAPYLPGLSDPKDAAEG
What are the official names of this protein?
Protein Rv0740.