PharMolix/UniProtQA huggingface dataset:
Protein: NHAB_YERPS
Sequence: MDITNRQAVLKNFLGNSPDWYKLAIMGFLIINPLVFFFVSPFVAGWMLVIEFIFTLAMALKCYPLQPGGLLAIQAVAIGMTSPHQVAEEIANNLEVLLLLVFMVAGIYFMKQLLLFVFTKLLLNIRSKTILSLAFCLASAFLSAFLDALTVIAVVISVSVGFYTIYHNVTSNHSDKDITDDSGIDNQDSHETLEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKSAGWNFADFFIRMLPVTLPVFIFGLLVCLLVEKFKLFGYGAQLPERVRQVLTEYDQQASAKRTKQEKMKLIVQAIIGVWLVLALALHLAEVGLVGLSVIILATSFCGITNEHSLGKAFQEALPFTALLTVFFAVVAVIIEQSLFTPIIQFVLQASPSAQLSLFYLFNGLLSSVSDNVFVGTVYINEARSAFEHGIVSLQQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVYMALPYTLVMTIVGLLGVEFLLVPMTEWLTQAGWISLPHITNGVAIPH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPD_SYNJB
Sequence: MISSTMAEKVVDPYAEALIALGSGQGLLDTFAADMRFIAEVLRATPELGQFLANPVIKAEAKKNLLQQVFADQIHPLLLNALKLLTDRRRIMFLGTVCRRFLDLQRKLQNIVLAEVTTAIPLTEAQQQSIRERVMDFTQASGVELQATQDPELLGGVVIKIGSQVIDLSLRGQLRRLALQLA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: USPA_HAEDU
Sequence: MYKHILVAVDLSEESLILLRKGAGLAEKCGAKLSLIHVDVNFSDLYTGLIDINMSSVQDGVIEETTKALDELALKIDYPVSQRLNGTGDFSQVLEEAVAKYQIDLLITGHHQDFWSKFMSSTRQVMNNVTVDMLVVPLIDE
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein A homolog.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_PSELT
Sequence: MKEKIHPEMKLVTVKCACGAEHKFYTTLENVRIDVCSNCHPLYKGMSGASLVIDSEGRIEKFRRKYKDQQY
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: TRPB_ACIAD
Sequence: MIDYTQYPDARGHFGIHGGRFVSETLMAALEDLENLYNRMKNDEQFLAEFDRDLAYYVGRPSPLYYAERWSKKLGGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQHGVATATIAARLGLECVVFMGAEDVKRQAMNVYRMRLLGATVIPVQSGSKTLKDAMNEAMRDWVTNVDSTYYVIGTVAGPHPYPQLVRDFQSIIGREARRQIQEQAGRLPDALVACVGGGSNAIGLFYPFLNDQDVKMYGVEAAGHGIETGKHSAPLNAGHVGVLHGNRTYLMSDPQGQIIETHSISAGLDYPGVGPEHSFLKDMHRVEYVPIDDNEALQGFRDLTRIEGIIPAIESAHAMAYVTKLAPTMDKDQIIIANVSGRGDKDLMTVARIDGIEMVEM
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: QUEA_ECOSE
Sequence: MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCPA_MACPY
Sequence: MKSAVMAVACAAAPGLRRPSAFNGAALTTSAKSSSAMKMSFESEIGAQAPLGFWDPLGLLADADQDGFERLRYVEVKHGRIAMLAIAGHLTQQNARLPGMLSNSANLSFADMPNGVAALSKIPPAGLAQIFAFIGFLELAVMKNVEGSFPGDFTLGGNPFGASWDAMSEETQASKRAIELNNGRAAQMGILALMVHEELNNKPYVINDLVGASYTFN
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.  Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
What are the official names of this protein?
Fucoxanthin-chlorophyll a-c binding protein A, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fucoxanthin chlorophyll protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein. Note=FCPs are probably transported across the endoplasmic reticulum membranes that surround the plastid via a signal peptide, followed by translocation across the thylakoid membrane via a transit peptide.
Protein: RS16_BRADU
Sequence: MSVVIRLARAGTKKRPVYHVVVADSRFPRDGRFIERLGYFNPLLPKDNEARLKLDMEKVKAWVAKGAQPSDRVSRFLDAAGVKKREARNNPQKAVPRKERKAQAEAAAKG
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SYE2_CERS4
Sequence: MTTVTRFAPSPTGYIHVGNLRTALMNWAIARKSGGTFILRLDDTDRERSKQEYSDGIMEDLEWLGLTWDRLERQSDRLDRYAEAADELRRAGRFYECFESPTELDLKRKKLLNMGKPPVYDRAALKLSDEERARLREERGGYWRFLLDQERIEWTDGILGPISIDAASVSDPVLIRADGQVLYTFASSVDDIDMGVTFIVRGGDHVTNTATQIQIMQALGGTPPSFAHHSLLTGAQGEALSKRLGTLSLRDLRARGVEPMALLSLMARLGSSQPVELFRTHEELLAGFDVGTFGAAPTKFDAEDLFPLTRHYVQGLPFEAVRGRIAALGVPDDLAEPFWRVAKDNIGVLEDLGGWWTLFSEGAEPQIDPEDEDFIRQAMTLLPPPPYGPESWAQFTAAVKEATGRKGKGLFMPLRKALTGQAHGPDMSEVMPLLQKVRAKG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_BEII9
Sequence: MAKKIAGYVKLQVPAGDAKPAPPIGPALGQRGLNIMEFCKAFNAKTAQMEKGTPIPVVITAYADRSFTFEMKLPPVSYFLKKASGIQSGAKTTGRGFIGKVTKAQVREIAEKKLPDLNCQSVDAAATMIEGSARSMGLQVVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: TDA1_YEAST
Sequence: MTTASSSASQLQQRLPEEKPWPQLSGSNADAQTFKCKYVTNHNSLGDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDMEKKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSYCACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFGLAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAFGYTPFDCTTDDETLECISKCDYYVDEQMMHDPKYEQFWNFVQCCFTIDPAVRRSAKNLKQHPFIKDYFATSNSLNTKDTPNFSFHPTIRRVSSTASMHTLRSPSKSRKTTTLAYLNMDGGSSETSTAFSSKMDLPDLYVDRTINSRERSLNRIRDTLKKTLSMTSLKPAGTFDYLHANKNGTSLSSSKSGLVKKNSTFVLDPKPPKNSLMNGCFSTTPESRSNFNTPKTLSRQGSSTSVKKYVNEVDLLLTPRTASMSSNDTTAINDYDTTNDKNPARKHAASFQVNVDDSDGDETMQI
What is the function of this protein?
Serine/threonine protein kinase shown to have protein phosphorylation activity in vitro.
What are the official names of this protein?
Serine/threonine-protein kinase TDA1, Topoisomerase I damage affected protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNTR_ALKCK
Sequence: MPTPSMEDYLERIYMLIEEKGYARVSDIAEALEVHPSSVTKMVQKLDKSDYLVYERYRGLVLTAKGNKIGKRLVYRHELLEDFMKIIGVDDTHIYKDVEGIEHHISWDAIDRIGDLVQYFQENQTRIDDLREIQKRNDFPEDE
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_GLAP5
Sequence: MAWVQIRLNSTDREAEKISDFLEDIGAVSVTFMNSQDTPIFEPLPGETRLWGNTDVVALFDAETDMKEIVSTLVKSKLVATDFPYKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWREIPDPNAVNVMLDPGLAFGTGTHPTTALCLTWLDSLDLTDKTVIDFGCGSGILAIAALKLGAKKAIGIDIDPQAILASQNNAEVNGVADRLQLFLTKDQPQNLIADVVIANILAGPLKELAPQIITLVKPQGNLGLSGILATQAESVCKAYQNSFKLDSIIEKEEWCRITGIKKH
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VILI3_ARATH
Sequence: MSGSTKVLDPAFQGVGQKPGTEIWRIENFEPVPVPKSEHGKFYMGDTYIVLQTTQNKGGAYLFDIHFWIGKDTSQDEAGTAAVKTVELDAALGGRAVQYREIQGHESDKFLSYFKPCIIPLEGGVASGFKKPEEEEFETRLYTCKGKRAVHLKQVPFARSSLNHDDVFILDTKEKIYQFNGANSNIQERAKALVVIQYLKDKFHEGTSDVAIVDDGKLDTESDSGEFWVLFGGFAPIARKVASEDEIIPETTPPKLYSIADGQVESIDGDLSKSMLENNKCYLLDCGSEIFIWVGRVTQVEERKTAIQAAEDFVASENRPKATRITRVIQGYEPHSFKSNFDSWPSGSATPANEEGRGKVAALLKQQGVGLKGLSKSTPVNEDIPPLLEGGGKLEVWYIDANSKTVLSKDHVGKLYSGDCYLVLYTYHSGERKEDYFLCCWFGKNSNQEDQETAVRLASTMTNSLKGRPVQARIFEGKEPPQFVALFQHMVVLKGGLSSGYKNSMTEKGSSGETYTPESIALIQVSGTGVHNNKALQVEAVATSLNSYDCFLLQSGTSMFLWVGNHSTHEQQELAAKVAEFLKPGTTIKHAKEGTESSSFWFALGGKQNFTSKKVSSETVRDPHLFSFSFNRGKFQVEEIHNFDQDDLLTEEMHLLDTHAEVFVWVGQCVDPKEKQTAFEIGQRYINLAGSLEGLSPKVPLYKITEGNEPCFFTTYFSWDSTKATVQGNSYQKKAALLLGTHHVVEDQSSSGNQGPRQRAAALAALTSAFNSSSGRTSSPSRDRSNGSQGGPRQRAEALAALTSAFNSSPSSKSPPRRSGLTSQASQRAAAVAALSQVLTAEKKKSPDTSPSAEAKDEKAFSEVEATEEATEAKEEEEVSPAAEASAEEAKPKQDDSEVETTGVTFTYERLQAKSEKPVTGIDFKRREAYLSEVEFKTVFGMEKESFYKLPGWKQDLLKKKFNLF
What is the function of this protein?
Binds actin and actin filament bundles in a Ca(2+)-insensitive manner, but severs actin filaments in a calcium-dependent manner, regardless of the presence or not of VLN1 (AC O81643).  Acts redundantly with VLN2 (AC O81644) to generate thick actin filament bundles, to regulate directional organ growth (PubMed:22209875) and in sclerenchyma development (PubMed:22563899).
What are the official names of this protein?
Villin-3.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
Protein: RS9_STRMK
Sequence: MAITQNYGTGRRKSSTARVFLRKGSGNITVNGRPLDEFFGRETARMIVRQPLELTKNTESFDILVTAAGGGTTGQAGAIRLGIARALVEYDETLKSELRKAGFMTRDAREVERKKVGLHKARRATQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CYB_PROCR
Sequence: MTNIRKSHPLIKIVNKSFIDLPTPPNISAWWNFGSLLGICLILQVLTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWVIRYMHANGASMFFICLFMHIGRGMYYGSYAFPETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVNKATLTRFFAFHFILPFIILALATIHLLFLHETGSNNPSGMTSDADKVPFHPYYTIKDILGLLLLVLALSTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIMSILILAIVPLLHTSKQRGMAFRPISQCLFWLLVADLLTLTWIGGQPVEYPFITIGQLASIAYFSIILILMPVSGIIENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SPH1_YEAST
Sequence: MISSELTNDQIIDLISDYKNFKRIIEASVPEDDRRRNQNRQNRNKDLTKLSNVQFWQLTTDVNDELMKRLTDSGADASLNDLDLKRGKAQSKLSRLKDAKFHKLILDIFTEIERRNLHHLDMGTHNNGLDEGDLNFYLNDTLFESFKINDDFMSVNGIISIEVFRELKTQFTLYFQNTLHRIDPVDTTTTRLPILLETIIKIAKLIGDLLPVLSSVSLQSSLENEIVYLKSALSHAITSTRYFLTYGDLIPRIVAQSSISEVIFAFCNIAQIVKIKSTSRDDISRNEGELSDIEAGMKPLKIIEKVKNEKNGKDISSLGDSGSTAVSFPSSGKPITKKSDMPVVVASPSISIIEKSESSIRESGKVRNNTSGETNLASVSPLKNTKNSSRITSEPSPREGLPLKVVSNSRSPSPQGNTLPLIGKFRQDYQASPPKKVITKPVAETAKPYANIPPAADVLYSPTVTKMRKFREKVQKFAPNSGLGLRISTSEENLNNSDVNSTTHNANINNLVEFVESKSMVVLPMAQGILNDVQASKSKLFKSARSVSRLCQNSIEIIPILESVIDMTTKAMVQKSFKLDLGEHCKEIIERLTDCSQKLSELCTYGCDSTKLGKKRFYQKLADILMEVTKRTRELVECVKMANRQTLSQDLSSFFNYRSVQ
What is the function of this protein?
Polarity-determining protein which forms a conjugate with the ubiquitin-like modifier HUB1.  Involved in bud site selection and cellular morphogenesis during conjugation.  Required for pseudohyphal growth.
What are the official names of this protein?
Protein SPH1, SPA2 homolog 1.
What are the subcellular locations of this protein?
Bud tip. Bud neck. Cytoplasm, cytoskeleton. Note=Sites of polarized growth as bud tip, bud neck and mating projection. Hub1 is necessary for the proper location to mating projections after pheromone alpha treatment.
Protein: RSMA_GEOSL
Sequence: MRGDGIRARKALGQNFLTDRSVLSRIAALVSAGAGERILEIGPGKGALTSYLAEQAGQLVAVELDDRLVPLLRGSFAGNPSVTIIEGDILDLDLRETLGRYGTPPWKVAANLPYNISTPVLFRLLDARDLFSRLVLMLQKEVGNRLAAGPGSKEYGVLSVLFQLHFDVTREILVRPGSFHPVPKVDSVVLLFVPLAQPRVDVGDEDYFRRVVKASFAMRRKTLWNCLKGGALGVPTDGIRDVLARCGIDEGRRGETLSLQEFASLTKGLLAAGGSL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PABB_STRLI
Sequence: MASCRMGARSALEPCQVDCLDEAADERCAETPRCHAELLESVTGASRMSRYSIIVLDPIGTIRAAEALTALVDADDVIFKDEDPLKGIRSVFELGDLDPTNHEEIEFQGGALGRFAYDIARRLEAIRDLGDRELAGPDAGTALYDLILYDHQDDVIWILVPNEAGEQDPSEDFRDLVNAWSYDDEFDIGAEFGANYTDDAYADGVDRLKDYLGSGDMYQVNLAQRRVGMISAEDYQLYIRLRDANPAPYMAYLDIDEGLLVASPERIILDEASDLDTRPIAGTLRGRPRAGGDDEDDGRAIDLLRVDKDRAERIMIVDLDRNDIARVGVGGSVKVREIMGLERYSGVMHLVSQVTGDLQEAIEAVDLIRAGFPGGTLTGAPKVRTMEIIDELEPQRRAAYCGSIGYIAYKGNIDFKIAIPTLYALAGQLFCQAGGGVVGDSVPDGEYRESFEKGNALIRGLEIRHGAVVAQSEDK
What is the function of this protein?
Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p-aminobenzoate (PABA) and tetrahydrofolate.  In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC (By similarity).
What are the official names of this protein?
Aminodeoxychorismate synthase component 1, ADC synthase, ADCS, 4-amino-4-deoxychorismate synthase component 1.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: RL2_PSE14
Sequence: MAIVKCKPTSPGRRFVVKVVNQELHKGAPHAPLLEKKSKSGGRNNNGRITTRHIGGGHKQHYRLVDFRRNDKDGIAATVERIEYDPNRTAHIALLLYADGERRYIIAPKGVSAGDQLIAGALAPIKPGNALQLRNIPVGSTVHGIELKPGKGAQIARSAGASAQLIAREGVYVTLRLRSGEMRKVLSECRATLGEVSNSEHSLRSLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGFPTKGAKTRGNKRTDKMIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PQBP1_PONPY
Sequence: MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSHEKPDRGHDKSDRGHDKSDRDRERGYDKVDRERERDRERDRDRGYDKADREEGKERRHHRREELAPYPKSKKAVSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASRTKQQD
What is the function of this protein?
Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development.  Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species.  May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner.  Can activate transcription directly or via association with the transcription machinery.  May be involved in ATXN1 mutant-induced cell death.  The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.  Involved in the assembly of cytoplasmic stress granule, possibly by participating in the transport of neuronal RNA granules.  Also acts as an innate immune sensor of infection by retroviruses, by detecting the presence of reverse-transcribed DNA in the cytosol.  Directly binds retroviral reverse-transcribed DNA in the cytosol and interacts with CGAS, leading to activate the cGAS-STING signaling pathway, triggering type-I interferon production.
What are the official names of this protein?
Polyglutamine-binding protein 1, PQBP-1, Polyglutamine tract-binding protein 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasmic granule. Note=Colocalizes with SRSF2 in nuclear speckles (By similarity). Colocalized with POU3F2. Colocalized with ATXN1 in nuclear inclusion bodies. Localizes to cytoplasmic stress granules (By similarity).
Protein: NUON_FRASN
Sequence: MSAATTVLAQGAAQKITPPSIEYSSLSPMLILFGVALAGVLVDAFAPPKARRVLQPLLAGAGFIGAFVAVVLLHAHRQVLAAGAVAIDGPTLFLQGTILVFALLSVLLVAERRLDSSGGALVASAAVVPGSRGSTAQRTSPDVQTEAYPLMVFSVSGMLLFVASNNLLVMFVALEILSLPLYLLCGLARRRRLLSQEAAMKYFLLGAFSSAFFLYGVAFAYGYAGSVELGRVADAVGTVGQNDTYLYLSLALLGVGLFFKIGAAPFHSWTPDVYQGAPTPITAFMAAGTKVAAFGALLRVFYVAFGGMRWDWRPVIWAVAILTMVVGAVLALTQRDIKRMLAYSAVAHAGFLLVGMAGSNIDGLRGAMFYLVTYGFTTIAAFAVVSLVRTGDGEASDLSQWQGLGRTSPLLAGTFAFLLLALAGIPLTSGFTGKFAVFQAAIAGDATPLVVVALVCSAIAAFFYVRVIVLMFFSEPLADGPVVVTRPTLTFATVGIGALMTLLLGVAPQPLLDLATTAATSGFVR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SDHF2_DICDI
Sequence: MFKSIKQIKSSIGFITTNTTRRNFCSNKIGGFTIKNVEDESKIKINNEISEIEKLRKKLLYQSKERGMLENDLLLGSFATLNIHKLTESQLRDYNLLLQQPDPDIFNWILKKAEVPEEFETEVLKLVQHHCKNDPLGYTRK
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LNRN_BACSU
Sequence: MKKILAICGIELSLIFKKPQNYLIMFAAPLLLTFVFGSMLSGNDDKVRLAIVDQDDTILSQHYIRQLKAHDDMYVFENMSESKASEKLKQKKIAGIIVISRSFQTQLEKGKHPELIFRHGPELSEAPMVKQYAESALATLNIQVTAAKTASQTAGENWKAAYKTVFAKKHEDIVPAVTRQTLSDKKEGAEASDTASRAAGFSILFVMLTMMGAAGTILEARKNGVWSRLLTASVSRAEIGAGYVLSFFVIGWIQFGILLLSTHWLFGINWGNPAAVIVLVSLFLLTVVGIGLMIAANVRTPEQQLAFGNLFVIATCMVSGMYWPIDIEPKFMQSIAEFLPQKWAMSGLTEIIANGARVTDILGICGILLAFAAITFAAGLKALRA
What is the function of this protein?
Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes (PubMed:26647299, PubMed:28461449).  Part of the ABC transporter complex LnrLMN that probably facilitates linearmycin removal from the membrane.  Responsible for the translocation of the substrate across the membrane (PubMed:28461449).  Also mediates KinC-dependent biofilm morphology (PubMed:28461449).
What are the official names of this protein?
Linearmycin resistance permease protein LnrN.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYGB_PARDP
Sequence: MPDLLIELFSEEIPARMQARARGDLKKLVTDGLVEAGLTYKSAGAFSTPRRLALAIEGLTAQSPTTREERKGPRTDAPEAALEGFLRSTGLTREQLEARDDKKGQVWFAVVTKPGRPAAEIVAEVLERAIRDFPWPKSMRWGSGSLRWVRPLHSIICLLSDESGASVVPLEIEGIGAGNTTRGHRFMAPDEIAVSGFEDYAAKLRRARVMLDAAEREAAIRQEAANLAFARGWEIVPDEGLLSEVAGLVEWPVPLMGAIEDRFLALPPEVLQTSMKEHQKFFSARNPKTGRIEGFVTVANIETPDHGETILKGNQRVLAARLSDAAFFWENDLREAKAGMADWAEGLRSVTFQSKLGSQADRIARIAALALEIAPLVGADADQAEQAARIAKLDLRSAMVGEFPELQGIMGRYYALEAGLPEPVADAARDHYSPLGPSDAVPSAPVSVAVALADKLDTLTGFWAIDEKPTGSKDPFALRRAALGVIRLLLVNGVRANLGQTFAKARPDADAADLLAFFHDRLKVHLRDQGVRHDIIDAVLSMPGNDDLVLLVNRATALSDVLKTEDGTNLLQGLKRAGNILAQAEEMDGVEYSFGADPKFAETDEERTLFAALDKAEPAIREAVRLEDFQAATQGIASLRAPIDAFFEAVQINSDNQILRRNRLNLLSRIRDAGRLIADFGRIEG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.