PharMolix/UniProtQA huggingface dataset:
Protein: SCN9A_RAT
Sequence: MAMLPPPGPQSFVHFTKQSLALIEQRISEEKAKEHKDEKKDDEEEGPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKAIFRFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTLSNPPEWTKNVEYTFTGIYTFESLIKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRKELEENETLESIMNTAESEEELKKYFYYLEGSKDALLCGFSTDSGQCPEGYICVKAGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEFTSIGRSRIMGLSESSSETSRLSSKSAKERRNRRKKKKQKMSSGEEKGDDEKLSKSGSEESIRKKSFHLGVEGHHRTREKRLSTPNQSPLSIRGSLFSARRSSRTSLFSFKGRGRDLGSETEFADDEHSIFGDNESRRGSLFVPHRPRERRSSNISQASRSPPVLPVNGKMHSAVDCNGVVSLVDGPSALMLPNGQLLPEVIIDKATSDDSGTTNQMRKKRLSSSYFLSEDMLNDPHLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHTFLIWNCSPYWIKFKKLIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNVLAVGNLIFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLIELFLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINVDCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSDNLTAIEEDTDANNLQIAVARIKRGINYVKQTLREFILKSFSKKPKGSKDTKRTADPNNKKENYISNRTLAEMSKDHNFLKEKDRISGYGSSLDKSFMDENDYQSFIHNPSLTVTVPIAPGESDLEIMNTEELSSDSDSDYSKEKRNRSSSSECSTVDNPLPGEEEAEAEPVNADEPEACFTDGCVRRFPCCQVNVDSGKGKVWWTIRKTCYRIVEHSWFESFIVLMILLSSGALAFEDIYIEKKKTIKIILEYADKIFTYIFILEMLLKWVAYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECVNTTDGSRFPTSQVANRSECFALMNVSGNVRWKNLKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSVNVNEQPKYEYSLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGCIFDLVTNQAFDITIMVLICLNMVTMMVEKEGQTEYMDYVLHWINMVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEAGINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSAPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGEGGEMDSLRSQMEERFMSANPSKVSYEPITTTLKRKQEEVSATIIQRAYRRYRLRQHVKNISSIYIKDGDRDDDLPNKEDTVFDNVNENSSPEKTDVTASTISPPSYDSVTKPDQEKYETDKTEKEDKEKDESRK
What is the function of this protein?
Mediates the voltage-dependent sodium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.  It is a tetrodotoxin-sensitive Na(+) channel isoform.  Plays a role in pain mechanisms, especially in the development of inflammatory pain.
What are the official names of this protein?
Sodium channel protein type 9 subunit alpha, Peripheral sodium channel 1, PN1, Sodium channel protein type IX subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.7.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.7/SCN9A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, neuron projection. Note=In neurite terminals.
Protein: LIPB_PSEPW
Sequence: MSLCLGFRELGLQPYEPVLEAMRRFTEQRSPDSQDEIWLVEHPAVFTQGQAGKAEHLLVPGDIPVVQTDRGGQVTYHGPGQLVAYLLLDVRRLGFGVRELVSRIEQTLIELLASYGVSAAAKPDAPGVYVDGAKIASLGLRIRNGRSFHGLALNVDMDLAPFRRINPCGYAGLAMTQLRDLAGPIELDEVRTRLRGQLVKHLDYAEQTTLTGGID
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAKLP_ARATH
Sequence: MELPWLSLTTFTLSLLIYFSSTTQAFKRCPNCGSTRVPYPLSTGLDCGDPGYRIRCDNYGSLWFDTLNGSTNPIKTIDPSGQRFVLRPPGFEQNKCVSVDIKYHGIQLDLNLPFNVSCSNTVIIMNCTKDGLDAYSSQGFNCSDNSLCHKFLNANLEARGNCRGVTSCCWYKTGASVNTYKVYRARPDMCSAYQSFMNLDLTIPVSKWGEPAVEILWEAPREPVCKSQGDCRDLLNSVCSNDSTNLGQKRCFCKKGFQWDSVNAVCEVNRCSKRKSCKRWSNLPLLGGLAGGVGAILIAGFITKTIVSKQNRRIAGNQSWASVRKLHRNLLSINSTGLDRIFTGKEIVKATDNFAKSNLLGFGGFGEVFKGNLDDGTTVAVKRAKLGNEKSIYQIVNEVQILCQVSHKNLVKLLGCCIELEMPVLVYEFVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLFELLTCKKAIDFNREEEDVNLVVFVRKALKEGRLMDVIDPVIGIGATEKEIESMKALGVLAELCVKETRQCRPTMQVAAKEIENILHGI
What is the function of this protein?
Putative serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
What are the official names of this protein?
Wall-associated receptor kinase-like 15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SYY_ECOK1
Sequence: MEILMASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEDGLQAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQSDPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM1A_CAEEL
Sequence: MRRILTLLLLFNVVRSSEAITGGVVNLRPKQIINSVGIGDRFGGIGTSSDESDHFKLLAADGDSLLVGARNAVYNLSLSTLSVNHKIDWKPPAEHIEECIMKGKSKTDCQNYIRVLARKSAGVSLVCGTHAFSPKCREYTVTEFGIRNTRQFDGQGISPYDPKHNSSALYVPGTNQLFVATVTDFVGNDALIYRKTIDETPSSKSAANIRTQSYDARVLNAPNFVATFAYKEHVYFWFREIASEAIDNNEEPQIYARVARVCKNDKGGARPANERWTSYLKARLNCSLPSGSSPFYFNELKAVSDPIDAGNNNHVVYTVFSTPDSDVRMSAVCKFSMKKIREEFDNGTFKHQNNAQSMWMAFNRNEVPKPRPGSCSPDSTKLPENTVSFILHHPLLHRPIPSVAAPLLVEGADRADLTQITVLPRVRAVGGHNYDILFIGTSDGKVLKVVEVDGNATVIQSATVFQRGVPIVNLLTTKESVVIVSADEIASLPVHNCAQQTSCSKCVQLQDPHCAWDSSIARCVHGGSWTGDQFIQNMVFGQSEQCPEGIIVREVFDDNESEAQPEAVSRSGYPKEHSTITVVLVAAVASLISLIIGAFIGIRVNRWAATSEPHRSASSTSGSDYDSFGRARLTRHDSLTTATKVDHGFVPQSKQSVDATSLVMSINATHHPMSMSQHGSGINTPSRDKNAIVTSINQNTLPRDYKVKKVYL
What is the function of this protein?
May function in growth cone guidance.
What are the official names of this protein?
Semaphorin-1A, CeSema.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PRC2A_MACMU
Sequence: MSDRSGPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGALQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHKDSQSASGEERPTEADGKKGNSPNSELPPPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPLAPSPASAPTPEKEPEESAQAPPAQCTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPAPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQQQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPTDPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPVSRFPLEEPAPPGPRPLPWPPGSDEGAKIQTQPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKAPKPDPLKIAKGKLAGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPPPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSSGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASTPGPEEALTTVTVAPPPRRAAAKSPDLSNQNSDQANEEWETASESSDFASERRGDKEAPPPALLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGAGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGPPQTPQGPSPRPPTRYEPQRVNNGLSSDPHFEEPGPMVRGVGGTPRDSARVSPFPAKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGPSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHLPGPPVQFDTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLGSGHCGPEPPSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGVALKGQFLDFSTLQAAELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKAPPSTYSGVFRTQRIDLYQQASPPDALRWIPKPWERTGPPSREGPSRRAEEPGSRGDKEPGLPPPR
What is the function of this protein?
May play a role in the regulation of pre-mRNA splicing.
What are the official names of this protein?
Protein PRRC2A, HLA-B-associated transcript 2, Proline-rich and coiled-coil-containing protein 2A.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RBS1_ACEAT
Sequence: MASIMMNKSVVLSKECAKPLATPKVTLNKRGFATTIATKNREMMVWQPFNNKMFETFSFLPPLTDEQISKQVDYILTNSWTPCLEFAASDQAYAGNENCIRMGPVASTYQDNRYWTMWKLPMFGCTDGSQVLSEIQACTKAFPDAYIRLVCFDANRQVQISGFLVHRPPSATDYRLPADRQV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 1, RuBisCO small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS17_NEIG2
Sequence: MSETKNVRTLQGKVVSDKMDKTVTVLVERKVKHSLYGKIIRLSTKIHAHDENNQYGIGDVVVISESRPLSKTKSWVVSELVEKARSI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SKA3_DANRE
Sequence: MNPSERFFSKLRKLTVYLETESSSLLHTSQNLKEDEEDEETGAQALYQLHSEVRALKRQVRDQVATHDTSSADLRSFIRRCLVLKQRTTEDIDSLKKHYEKYGYRPRISRLGSTEVNCTKEAEERAERDAEKLDAAEEDEETERGDCDKVDQSVTPEKMPPPVDQLQTPKLSDFGLSALQFQRVLGEAEVPLSAAPESAIALSSPPILMNLQPPQPKTPKCSLSMEEDALTPRLEDFGISEYTMCWNNDFTMDLFNKKPPKNRSERNENVLKPHNVFSNTSSVLNKDVANKSLESPEPPEFCTPGFKIAKNHVPSTPLFNGKNDLNSPPRLNNNCPSTPELPAFETPFVSKLIKKEDREEESKIHSESQENSLRLPDLSTTNGTSWNDAPEMPKMLRYEEEALPEMPILQSNFGSSLAFKNTSGESLSRMKTGAGHMLEMKQTSVPVPEDGFNQDWCLSTPKVRVKFPAEPCTPEMPDMSSVTQDILKLVAQCKY
What is the function of this protein?
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies.  The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner.  In the complex, it mediates the microtubule-stimulated oligomerization.  Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Spindle and kinetochore-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the SKA3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner.
Protein: WDR44_MOUSE
Sequence: MASESDTEEFYDAPEDVHLGTGYPVGSPGKVGLLSFKEAENTANQAGNESPVQELRQDVSKKIIESIIEESQKVLQLEDDSLDSKGKGLSDEATAGPSVAGTEFSNIPGLLAIEHELQQDSEKAESQNVAEESELETQKCFPSDETCEKSEKTVDETDNLTEVSSGEQLDASGLEAETLNKEALEVKEGDVLDPASLDTLSTTDFAAVEEVAPAKPPRHLTPEPDIVASTKKPVPARPPPPTNFPPPRPPPPSRPAPPPRKKKSELEFEALKTPDLDVPKENITSDSLLTTNMASENTVRDSLPSLDLASATSGDKIVTAQENGKAPDVQTVAGEVMGPQRPRSNSGRELTDEEILASVMIKNLDTGEEIPLSLAEEKLPTGINPLTLHIMRRTKEYVSNDATQSDDEEKLQSQQTDTDGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNIVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDMGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKLEGIDKYEDAEVLDSTSTGIVKTDNTEVLLSADFTGAIKVFINKRKTVS
What is the function of this protein?
Downstream effector for RAB11.  May be involved in vesicle recycling (By similarity).
What are the official names of this protein?
WD repeat-containing protein 44, Rabphilin-11.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, perinuclear region. Endosome membrane. Golgi apparatus, trans-Golgi network. Note=Colocalized with RAB11 along microtubules oriented toward lamellipodia.
Protein: KITH_JANSC
Sequence: MAKLYFNYSTMNAGKSTLLLQASYNYIERGMQTYLLTANFDDRAGMGRIGSRIGIEAEADTYTQSDDLFAKIDARLKAGPCACVLVDEAQWMTRDQVWQLARAVDDLGVPVMCYGLRVDFRGELFPGSAALLALADEMREVRTICHCGRKATMVIRVGEDGNALAEGAQIEVGGNDRYISLCRKHFREAVGDVPV
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_BLOFL
Sequence: MLLGIITLFPDMFNAITRYGVVGRSVRKGGLVIKIWNPRDFTYDQYHKVDDRPYGGGVGMIMMIQPLKRAINQAKNDLGCDAKVIYLSPQGKRLCQKYVYDLAYNNQALILVCGRYQGIDERLIKMEIDEEWSIGDYVLSGGELASMVLIDAMARVLPGTLKNRNSQKSDSFFENKLDCPYYTRPKIYEGMQVPSVLLSGNHRDINKWRLKYALGNTWIKRPDLLKKIQLTQEEQLLLTEFKNEYLSG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_CHLPD
Sequence: MSDPVIKRALVSVSDKTGIVDFCRELSLLGVEVFSTGGTLKTLQDAGIAAASISTITGFPEIMDGRVKTLHPKIHGGLLAVRENPDHVNQANENGISFIDLVVVNLYPFEATVAKPDVTFEDAIENIDIGGPSMLRSAAKNNESVTVVTDSADYALVLQEMRNNNGATKRETRLALALKVFELTSRYDRAIASYLAGAQHEADSSMTVKLERELDMRYGENPHQSAGLYRLTDENGTRSFSDYFEKLHGKELSYNNMLDIAAAVSLIEEFRGEEPTVVIIKHTNPCGVAQAPTLAEAYRRAFSTDTQAPFGGIIAFNHPLDMEAATAVNEIFTEILIAPAFEDGVLEMLMKKKDRRLVRQTSALPKGGWEFKSTPFGMLVQERDSKIVTKEDLTVVTKRQPTEEEVADMMFAWKICKHIKSNTILYVKNRQTFGVGAGQMSRVDSSKIARWKASEVNLDLHGSVVASDAFFPFADGLLAAAEAGVTAVIQPGGSIRDNEVIEAADANNLAMVFTGMRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: S35G5_PANPA
Sequence: MAGSHPYFNLPDSTHPSPPSAPPSLRWCQRCQPSDATNGLLVALLGGGLPAGFVGPLSRMAYQASNLPSLELLICRCLFHLPIALPLKLRGDPLLGPPDIRGRACFCALLNVLSIGCAYSAVQVVPAGNAATVRKGSSTVCSAILTLCLESQGLSGYDWCGLLGSILGLIIIVGPGLWTLQEGTMGVYTALGYVQAFLGGLALSLGLLVYRSLHFPSCLPTVAFLFGLVGLLGFVPGLFVLQTPVLPSDLLSWSCVGAVGILALVSFTCVGYAVTKAHPALVCAVLHSEVVVALILQYYVLHETVAPFDITGAGIVLGSIAIITARNLSCERTGKVEE
What are the official names of this protein?
Solute carrier family 35 member G5, Acyl-malonyl-condensing enzyme 1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the SLC35G solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SECY_PYRFU
Sequence: MGARDIIYALERWFPEVERPKRRVPLRERFMWTGVALILYYVLAEIPVYGIPERIQDYFQFLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFFEAAVWILGGAFGRVGVDVTYAIAVLMILQLAMGGIVLIILDELVSKWGIGSGISLFIAAGVSQTILTRSLNPLTDPNIIDPLTGQPAIVGAIPYFIQHILKGDLWGAIYRGGSAPDMLSVVATIVVFFIVVYFESMRVEIPLGYRGVTVRGSYPIRFLYVSNIPIILTFALYANIQLWARVLDRLGHPWLGRFDPTTGSPISGFVLYVIPPRNIFSVIDNPVRAIVYLILTVIFSLLFGYLWVELTGLDARSIARQLQRAGLQIPGFRRDPRTLEKVLQRYIPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQITEMFPALRKLFGA
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.  Complements an E. coli temperature-sensitive secY mutation; deletion of the last 15 residues prevents complementation, which may indicate a role of this region in translocation.
What are the official names of this protein?
Protein translocase subunit SecY, Protein transport protein SEC61 subunit alpha homolog.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLME_PSYIN
Sequence: MAQKDHPNGPKKSASASSKRWMYEHVNDFYVKEATKKGLRSRAVFKLEEINKKDKLIRSGMTVVDLGAAPGSWSQWAVDTVGLKGKVIACDILPMDSIAGVDFLQGDFREDAVVNALLARIAGHKVDVVLSDMSPNMTGTVGIDQPKSMYLVELALEMCKEVLVKEGSFVVKVFMGSEFDLFMSEARKCFKSVKTRKPDSSRSRSREVYVVATGYKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPXH_STAS1
Sequence: MTEELRLIQPNSREDANLSPVSKIEIYSFFDPFSKECFKLSAILSKLRIEYKQYISIRHILNPSLRVLTKCQAQSTSDLDNIALAYKAAELQGRIRAERFIHLVQNEIIPKRDIITESMVNSCISNAGLDYEVFKEDLNSSCLKESLQVDLHIAREMEIEEAPSLVFFNEDVHEEGLKVEGLYPYHIYTYIINELIGSTIEKELPPSLEDYIQQQQLVTKEELLTIYEWPEKLMNKELKKLALQQKIEKLKSPDGKFWKAKN
What is the function of this protein?
Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions.  Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
What are the official names of this protein?
ClpXP adapter protein SpxH.
What is the protein family that this protein belongs to?
Belongs to the SpxH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UQCC5_HUMAN
Sequence: MFTRAQVRRILQRVPGKQRFGIYRFLPFFFVLGGTMEWIMIKVRVGQETFYDVYRRKASERQYQRRLEDE
What is the function of this protein?
Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation (By similarity).  Mediates early complex III biogenesis (By similarity).  Participates in regulating the levels of electron transport chain proteins, and therefore energy supply, in response to changes in energy demand (By similarity).  Also involved in the first steps of cytochrome c oxidase complex (complex IV) assembly (PubMed:34969438).
What are the official names of this protein?
Ubiquinol-cytochrome-c reductase complex assembly factor 5, Small integral membrane protein 4.
What is the protein family that this protein belongs to?
Belongs to the UQCC5 family.
Protein: Y2594_XANP2
Sequence: MIASHKPNVPSGGSSFLDGQLLIAMPTMRDEQFARTLVYLCAHSAEGAMGIVVNQPASHIDFTDLLVQLDVIPSSERILLPKSAGAVKVLRGGPVETGRGFVLHSADYFVENSTLPIDDGICLTATLDILKAIAGGRGPRSAVLALGYAGWAPGQLETEIQANGWLNCPADSDLIFGEGVDTKYNHALRKLGVDPGMLSSEAGHA
What are the official names of this protein?
UPF0301 protein Xaut_2594.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RSMJ_SALHS
Sequence: MQICLMDETGATDGALSVLAARWGLEHDEDNPMALVLTPQHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLTRGYADADIGGWLQERLQLIHVSSLTALTDITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVKRPDYAPPLADVATPNAIVTKGHRFDIYAGTPLTE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_RHILO
Sequence: MSKNPIHIIGGGLAGSEAAWQAAQAGVPVVLHEMRPVRGTDAHKTDGLAELVCSNSFRSDDAENNAVGLLHAEMRLAGSLIMSAGDANQVPAGGALAVDRDGFSDAVTKKLEAHPLISIQREEVSGLPPADWDQAIIATGPLTAPSLARSIAEATGADALAFFDAIAPIIHFDTIDMDTCWFQSRYDKVGPGGTGKDYINCPMDKDQYLAFVQALIDGQKTEFKQWEGTPYFDGCLPIEIMAERGVETLRYGPMKPMGLTNAHNPMVKAYAVVQLRQDNALGTLYNMVGFQTKLKHAEQVRVFRTIPGLENADFARLGGLHRNTYINSPTLLDQSLQLKSRPGLRFAGQITGCEGYVESAAIGLLAGRFAAAERLGQAPSLPPLTTAFGALLNHITGGHIVSDDEPGKRSFQPMNVNFGLFPPVEAVKIEGKRLRGKDKTVAKRHAITSRALGDCRQWLGLPAPTETAEAAE
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRVP_BUNCA
Sequence: ESSNKRENQKQIVDKHNALRRSVRPTARNMLQMEWNSNAAQNAKRFADRCTFAHSPPHLRTVGIFSC
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein bucarin.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK_GEOUR
Sequence: MSIRYIDEISDLREKKIFMRVDFNVPLDEHQNITEDTRIRAVLPTINYALDYNAKVVLASHLGRPKGERNAKYSMAPAAKRLSRLLGKEVKLAPDCIGDGVSKIIDSMQPGDVVMLENLRFYPGEEKNDDDFAKALADHCDIYVNDAFAVSHRAHASVEAITKFFPIVAAGFLMKNEMSYFEKSMKNPIRPLVAILGGAKVSGKLEVLENLCNKVDKVIIGGGMAFTFLKALGYNVGKSLVEENLLETALNTYNKAREKGIKFYLPVDCVVADQFNPAAETKVTTIQEIPEGWMALDIGPATVTLFSTALQNAKTIVWNGPMGVFEMDAFSRGTFAMVSAVANSYALTIVGGGDTDVAVHRAGEYAKISYISTGGGAFLELLEGKKLPGIKVLEDNGHK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.