PharMolix/UniProtQA huggingface dataset:
Protein: RNH2A_DROME
Sequence: MSDQEDVVVKKEKKCIENIDENDEEPDDVDFKDSGKISSLKALGPFIAGKENSRNTVYLSDVPDICKDKPCMLGVDEAGRGPVLGPMVYGISYCPLESNKALEDLGCADSKQLTEGKRDIIFNDINTKEYATSCVGWAVEIISPNTISTSMYRRSKCSLNEVSMDSAMGLIQQAIDAGVNIAEVYVDTVGPPEKYQEKLLKRFPSFKITVAKKADSTYPIVSAASICAKVTRDHALKVWSFPEGLVIKDNEFGSGYPGDPVTRRFLTEYIDLVFGFPRLVRFSWSTAENALADKAYDMEFDEPDSEKPKYAGTKLTKFFKGTTKSGEIIREECRFFKQRHLESVMEF
What is the function of this protein?
Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids.  Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication.  Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).
What are the official names of this protein?
Ribonuclease H2 subunit A, RNase H2 subunit A, Ribonuclease HI large subunit, RNase HI large subunit, Ribonuclease HI subunit A.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. Eukaryotic subfamily.
Protein: SERA_SHIFL
Sequence: MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY
What is the function of this protein?
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway.  Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
What are the official names of this protein?
D-3-phosphoglycerate dehydrogenase, PGDH, 2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: TP4AP_MOUSE
Sequence: MAAAPAAAGAGASRGRRLAATAAAWGGWGGRPRPGNILLQLRQGQLTGRGLVRAVQFTETFLTERDKLSKWSGIPQLLLKLYATSHLHSDFVECQSILKEISPLLSMEAMAFVTEDRKFTQEATYPNTYIFDLFGGVDLLVEILMRPTISIRGQKLKISDEMSKDCLSILYNTCVCTEGVTKRLAEKNDFVIFLFTLMTSKKTFLQTATLIEDILGVKKEMIRLDEVPNLSSLVSNFDQQQLANFCRILAVTISEMDTGNDDKHTLLAKNAQQKKSLSLGPSAAEINQAALLSIPGFVERLCKLATRKVSESTGTASFLQELEEWYTWLDNALVLDALMRVANEESEHNQAPTVFPSLGTSEEGGLPHTSARAQLPQSMKIMHEIMYKLEVLYVLCVLLMGRQRNQVHRMIAEFKLIPGLNNLFDKLIWRKHSASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNELSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEHILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQVDMKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQRMEHSKKYPGFLLNNFHNLLRFWQQHYLHKDKDSTCLENSSCISFSYWKETVSILLNPDRQSPSALVSYIEEPYMDIDRDFTEE
What is the function of this protein?
Substrate-recognition component of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control.  The DCX(TRPC4AP) complex specifically mediates the polyubiquitination and subsequent degradation of MYC as part of the DesCEND (destruction via C-end degrons) pathway.  The DesCEND (destruction via C-end degrons) pathway recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  The DCX(TRPC4AP) complex specifically recognizes proteins with an arginine at the minus 3 position (R-3 motif) at the C-terminus, such as MYC, leading to their ubiquitination and degradation (By similarity).  Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome (PubMed:14585990).  Involved in JNK activation via its interaction with TRAF2 (PubMed:16876162).  Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1 (PubMed:20458742).
What are the official names of this protein?
Short transient receptor potential channel 4-associated protein, Trp4-associated protein, Trpc4-associated protein, Protein TAP1, Rabex-5/Rin2-interacting protein, TNF-receptor ubiquitous scaffolding/signaling protein, Protein TRUSS.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: CWC26_YARLI
Sequence: MDEYLAKKYGSKPKKTKKRKLVEGLDVDTAPITQRQTQQAPPPPRAKGGWKTLSGKAIDPVEETVYRDASGNIISVDDQISVLQQRQQEKEAAERRKKENLLGAVQVEEARKRQAKEEAMKHTKVTVHADDKEYNEERQNRAIYADPAAKFGKATPKASTTSSGGALPSYTGSFPSNRFNIKPGCLWDGNDRSNGFEAKWLSRQEEMKRQADVDYQNEMDF
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC26.
What is the protein family that this protein belongs to?
Belongs to the CWC26 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CH10_STAAS
Sequence: MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_BRUAB
Sequence: MSFFDSYRKKMQMPSKEEVLPGRVQPIPTAAAHFVSGHPLKGPWPDGMKQVLFGMGCFWGAERLFWQVPGVYVTAVGYAGGITPNPTYEETCTGLTGHAEVVLVVYDPKVVTLNELLALFWEEHDPTQGMRQGNDIGTTYRSVIYTFNAVDRAVAEKSRDAYSQALASRGLGPVTTQIADAPDFYYAEDYHQQYLAKNPDGYCGLRGTGVSCPIPLAH
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TUP1_CANAW
Sequence: MYPQRTQHQQRLTELLDAIKTEFDYASNEASSFKKVQEDYDSKYQQQAAEMQQIRQTVYDLELAHRKIKEAYEEEILRLKNELDTRDRQMKNGFQQQQQQQQQQQQQQQQQQQIVAPPAVPPAPPTPVTSLSVIDKSQYIVNPTQRANHVKEIPPFLQDLDIAKANPEFKKQHLEYYVLYNPAFSKDLDIDMVHSLDHSSVVCCVRFSRDGKFIATGCNKTTQVFNVTTGELVAKLIDESSNENKDDNTTASGDLYIRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLRTSQCSLTLSIEDGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQIASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVIFWDQASGNPLLMLQGHRNSVISVAVSLNSKGTEGIFATGSGDCKARIWKWTKK
What is the function of this protein?
Represses transcription by RNA polymerase II.  Represses genes responsible for initiating filamentous growth and this repression is lifted under inducing environmental conditions.
What are the official names of this protein?
Transcriptional repressor TUP1.
Protein: LGI3_PANTR
Sequence: MAGLRARGGPGPGLLALSALGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGVSACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTRLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA
What is the function of this protein?
May participate in the regulation of neuronal exocytosis.
What are the official names of this protein?
Leucine-rich repeat LGI family member 3, Leucine-rich glioma-inactivated protein 3.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Synapse, synaptosome. Note=Found in the synaptosomal membrane fraction.
Protein: CNBP_BOVIN
Sequence: MSSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA
What is the function of this protein?
Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (By similarity).  Has a role as transactivator of the Myc promoter (By similarity).  Binds single-stranded RNA in a sequence-specific manner (By similarity).  Binds G-rich elements in target mRNA coding sequences (By similarity).  Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (By similarity).
What are the official names of this protein?
CCHC-type zinc finger nucleic acid binding protein, Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum.
Protein: NAGB_VIBCM
Sequence: MRLIPLKAAAQVGKWAAAHIVKRINEFQPTAERPFVLGLPTGGTPLATYKALIEMHKAGEVSFKHVVTFNMDEYVGLAADHPESYRSFMYNNFFNHIDIQEENINLLNGNTDDHEAECKRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTEDTRIANSRFFDGDINQVPKYALTIGVGTLLDAQEIMILVTGHNKALALQAAVEGSVNHLWTVSALQLHPKAVIVCDEPSTQELKVKTVKYFTELEAKNIVGF
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RPO11_NANEQ
Sequence: MITIPTEVKILEETDNLIKVQFKGETHTLFNALKEIAYTINGVKKAAYFIEHPLKDNNYFIIETDGSIKARDALIQALKKLKEELLNFKDWYYSNL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTPB1_RAT
Sequence: MAAERSRSPVDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELDLTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADVILLRERQESGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSSKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLSKREEGGPSGVPAAGPPSTGDEASSLGTTQAATSSGLQPQPKPSSGGRRRGGQRHKVKSQGACVTPASGC
What is the function of this protein?
Promotes degradation of target mRNA species.  Plays a role in the regulation of circadian mRNA stability.  Binds GTP and has GTPase activity.
What are the official names of this protein?
GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. GTPBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2292_LISMC
Sequence: MWGYIHLISWVAIVVLTVTALLIYSKSTKSFTMLQMINRVFYILVILSGIMMVKYSIEQSWILAIFKILMGIIVIGVVEMLLSYRKQQKPTGMFLMIFVIVVVITISLGFYLSGGYPLFN
What are the official names of this protein?
UPF0344 protein Lm4b_02292.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABG6_BRANA
Sequence: ATAQEQPEGEAPDKVESPVVXXXEAXIVLVNYAREADVDAMMKDAVDYWGQIDVIANNAGITVIALNLTGVFLCSQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGFIASEMTAKLGEDMEKKILGTIPLGRYGQPEDVAGLVEFLALSPAASYITGQTFTIDGGIAI
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase, 3-ketoacyl-acyl carrier protein reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Note=And non-photosynthetic plastids.
Protein: CY550_PORPU
Sequence: MLKRSSWLATLLGLLTVASVSTIVYAIELDEATRTVPLESSGRTVVLTPEQVKRGKRLFNNSCAICHNGGITKTNPNVGLDPESLGLATPQRDNIEALVDYMKDPTSYDGAESIAELHPSIKSAEIFPKMRNLTDEDLFTIAGHILLQPKIVSEKWGGGKIYY
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: RHBL3_HUMAN
Sequence: MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAYTLLDLKLPPPP
What is the function of this protein?
May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
What are the official names of this protein?
Rhomboid-related protein 3, Ventrhoid transmembrane protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: STP_BPLZ5
Sequence: MSNFHNEHVMQFYRNNLKTKGVFGRQ
What is the function of this protein?
Anticodon nuclease cleaves the tRNA(Lys).  It cleaves near a pyrimidine base to generate 2':3'-P> and 5'-OH termini.  Stp activates the host prrC protein probably by counteracting prr masking.  Stp also inhibits EcoprrI restriction.  Stp probably alters the conformation of EcoprrI and, consequently, of prrC, allowing activation of the latent anticodon nuclease.  Presumably, stp evolved to offset a DNA restriction system of the host cell but was turned, eventually, against the phage as an activator of the appended tRNA restriction enzyme.
What are the official names of this protein?
Anticodon nuclease activator.
Protein: PSBI_OSTTA
Sequence: MLTLKILVYTVVSFFVSLFIFGFLSNDPGRNPNSKDFE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NFUA_SHEB2
Sequence: MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTSQAECGVSYCPPDAVESDDIEIEFTGFNAMVDEKSAPFLEDATIDFVTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEINPQLAGHGGNIMLVEITKEGVAVLQFGGGCNGCSQVDITLKDGIEKQLLDMFPGELTGVRDVTDHQHGEHSYA
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: TBCC_BOVIN
Sequence: METGGLSAAALANGDLGSQRERTLVPERLQKREHERQLEVERRKQKRQDQEVEEEKSDFFAAAFARERSAVEELLESGESVERLEEAAARLQGLQKLINDSVLFLAAYDLRQAQEVLARLQAALAKRRQELQPKKRFAFKTRKKDAASATQVASAPDAPAAEGSLTSPPPLKEEGDFDSSWICGFSNLQSQVLEKRAEELHQQDVLLTQLRNCTIKLYGNPNTLRLTKAQGCTLLCGPVSTSVFLEDCSDCVLAVACQQLRVHTTKDTRIFLQVTSRAIMEDCTGIQFAPYTWSYPGIDKDFEGSGLDKNKNNWNDVDDFNWLARDVASPNWNVLPEEERRIQWD
What is the function of this protein?
Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
What are the official names of this protein?
Tubulin-specific chaperone C, Tubulin-folding cofactor C, CFC.
What is the protein family that this protein belongs to?
Belongs to the TBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Detected predominantly in the photoreceptor connecting cilium.
Protein: PDXJ_EHRCR
Sequence: MSDVALGVNIDHVATLRNARNVDYPDIVEVANIAVSNGADFITVHLREDRRHIKDDDVFRLKNSLKVPLNLEIAPTDEMLSIAIKVRPKCVCLVPEKRQELTTEGGLDVKRAFSYLISFIEKLHTYNIDVTLFIEPDVDQIDQAKKLSADNVELHTGKYCNNTTQSELSQVIKAAEYCYQRNIGCHAGHGLNYQSAAIIAKVPYISALNIGHFLICESVLHGIGTSVHKMKKAIASAPN
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCC2_MOUSE
Sequence: MSSTSSNPDDGDTTEQSQLGLDTVIKKLEDTILSPMARREDRALTVRGEGQRASPTPVPARIREIVSSSLGEEPLSGLREPPATTSHAREESELLQEELTRLEDLLAQADAEREELASRCHMVSQRLQARLDTTEARLRKSELEHSMDLEEALSRLEASQQRSMGLSQVNTLLRQQLEHMQKANDTLARELTRATHSLVHLQRKLELQESQRLSLRQPRDILPLWRQAKALQTHLAELRASTERGLTDVQADMTRTAQRLHMACLNLDSHLRLTASSMTSDLEQRLREQAREMLQLQGQWAAEKVALQARLSEQTLLVEKLSVQKEQGERAILTLKSDIQRLKSRRSGGQLAVDELRDEVESLHHVLASIKEVAQSDAMCPELAWSSSIEVREAQARLRSPPRSVSPHQRMSPARTSSPTSLHPALQAVQAAIERRQQREQELRLRLESSQEEAAGLREQLSGYRQELRTSQRLLQDRAQEHEDLLGQLEAQRQEAQLSQASVHLLEREKEALETTMEELRAKADIREAETQKLEVTNAELRRSLLLRAEQKAELAQQSERSLRELEASQGRVEQLEEKVSGLRKELATSREALSSMQLQRDILETEKESLHGALAQAESGNADLELLVTRLKAEGMEQQDSLAKMAALLEGLSQDKGTLNHLALQLEQERDQLREQQKMLQQEQAGMREQLTQTGQQLGLIRAERRSLKETCGHLEQKQDHLEKQVVLLGQENAQLREQVGQVTNKKQALEKQLAQSLQDQEAQMDILQEALHEKNTLSEERAQLLAKQEALERHSELVTKEAADLRAERNSLENSLFEAQRLTTQLQTQQEQLEGKAEAAQLARRALQVEIERLKSDWEVRETKLQLHLGQLQQQAAQQEQEAQLALERQELAHTEDLARLHREKDTLSLSLAEEKEAAARWMEQQKELLTRSAADREALQGEIQNLKQERDESLLQLEHEMQQALSLKDAEKSLLSKELSGAHRELERARQEAQNQQVQAEATVTTMTKELRTLQVQFEEAISTHQREADTLREKLREIAAERSSVRREAEELQAQLNVAHERLAELRQELQASEESREGLQREALGARRALEDEVQEKDVLQHSNTELRASIHRAEQEKASLKRSKEEQEQKLLLLQEAQVAAQKEAYELRTRLQELERAQRDTRRKLQERHRQVRTLEAENQRKRQEVSDLQAQVSRDAQHRQKNLQESLELQRQVAEAQAAHDGVQKEVLGLRQKLAEVEASGETRAKQLEGHLCESQRAEQTLQAELCRITRKLQEASNQADSLQRSLDNACSRVHVLEQELAKAEGARCNAEAQLGRLWSTLCSGLGQSRNLLASPKRPHSPTTGSSQTRPGRQRTSPPTRSYSPARWPSPVPVDPKSEVIDVAFVRDALRDLVQGLLEAQQERDNSGIQVANLSSQLSEAERERLRLQSRVEQLQRDLADAEEGQRRAESALQSAQAARALQKEALQRLETEHLASARAAGQERRRLQEQVDTLRQALEESSRPSQSLADKGRLLEQPLQQVLPHSRRDRAERRALREQTTSLRTERARLQGELAALRTRLIQTEQETLKKEEDRAMLGAKKELLLQSLSHLHQEVDGALRQSQQLQVASLKKRLDKEVWQRQQQAHSD
What are the official names of this protein?
Ciliary rootlet coiled-coil protein 2.
What is the protein family that this protein belongs to?
Belongs to the rootletin family.
Protein: GP38_BPSP1
Sequence: MSVQIKHGNKTFVVDPSGDVKEGSYVLYLYEYRLGEVDVGRVSEVANDGRLYLDGPGVIVTLDQPFILLKEVVEEEEDEDDRIDAEFHNDPLLRKLENTTEKLTPEETQLAQWTTMTRVFSHDLKKGIPYAIKHKNSGNILYGLYSGLLNPVTALFRHLNEESKISIEQLKSGLIEIYEVVEDEEESIWN
What are the official names of this protein?
Putative gene 38 protein.
Protein: VM1A_AGKCL
Sequence: MIQVLLVTLCLAAFPYQGSSIILESGNVNDYEVVYPRKVTPVPRGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLELSDSEAHAVYKYENVEKEDEAPKMCGVTQNWESYEPIKKAFQLNLTPEQQGFPQRYVELVIVADHRMNTKYNGDSDKIRQWVHQIVNTINEIYRPLNIRFALVGLEIWSNQDLITVTSVSHDTLASFGNWRETDLLRRQRHDNAQLLTAIDFDGDTVGLAYVGGMCQLKHSTGVIQDHSAINLLVALTMAHELGHNLGMNHDGNQCHCGANSCVMPSVLSDQPSKLFSDCSKKDYQTFLPVNNPQCILNKPLRTDTASTPVSGNELLEA
What is the function of this protein?
Snake venom zinc metalloprotease that has fibrinolytic activity.  The recombinant enzyme cleaves both alpha- and beta-chains of fibrinogen, but not the gamma-chain.  The recombinant protein does not produce hemorrhage in mice.  Cleaves the peptide substrate Abz-LVEALYQ-EDDnp at the Ala-Leu bond in vitro (PubMed:12651104).
What are the official names of this protein?
Snake venom metalloproteinase ACLF, SVMP, ACLF-I, Metalloproteinase VMP-I, AclVMP-I.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DEOC_YERPB
Sequence: MTTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQQLAGSSVKVCSVIGFPLGAGLTAAKAFEAQAAINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAATPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFSTGGAKEEHVKLMRATVGPVMGVKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_VIBC3
Sequence: MNPRRKKRLGVVLAILFGLSATIGLIIYALNQNMDLFYTPTELVYGKEGKKPEIGQRLRIGGMVVEGSVKRDPNSLKVSFDLHDVGPSITVTYDGILPDLFREGQGIVAQGVLVEPTKIEAFEVLAKHDENYMPPEIAEAMKKTHAPLQYSQEQKQGSDQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: GATA_MORCA
Sequence: MTDLHHLSVHELADGLKNKQFSSHELVEHFANRINRLDGQINSFITKDFDNALAQAKLADKLRAKGDNRPLLGVPMAHKDNLCTKGVLTTAGSKMLYNFVSPYDATVVDSIANSGFVSLGKLNMDEFAMGSDNESSYFGAVHNPWDVQRVPGGSSGGSAAAVAAGFVPVATGSDTGGSIRQPASFCGITGIKPTYGRVSRYGMIAYASSLDQAGTFGKSALDCAYLLAPMAGYDPKDATSINRPSEDYVADILATKTDGKPLAGKKIGVAKAYFGAGLDSEVEKSIRTALAKYEELGAKIVEVDITDPAITLATYYLLAPAEASSNLSRYDGVRFGYRCENPKDLHDLYTRSRSEGFGAEVQRRIIMGTYALSAGYFDAYYTKAQKVRRLIVDDFKKAFEKCDIIASPTAPTPAYKLGESLDPASIYLLDVYTIGVNLAGLPALSHPVGQANGLPVGLQLISKHWAESELLKTAHIYQSHTDFHQAKADLVK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.