PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_STRP7
Sequence: MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEDQIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIETKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAMLALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: KBX1_MESGB
Sequence: MQRNLVVLLFLGMVALSSCGLREKHFQKLVKYAVPEGTLRTIIQTAVHKLGKTQFGCPAYQGYCDDHCQDIKKQEGFCHGFKCKCGIPMGF
What is the function of this protein?
Blocks voltage-gated potassium channels.
What are the official names of this protein?
Potassium channel toxin Meg-beta-KTx1, MegbetaKTx1, Beta potassium channel toxin 1.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIO2_SYNY3
Sequence: MSLLEITDAEFEQETQGQTKPVLVYFWASWCGPCRLMAPAIQAIAKDYGDKLKVLKLEVDPNPAAVAQCKVEGVPALRLFKNNELVMTHEGAIAKPKLLELLKEELDFI
What are the official names of this protein?
Thioredoxin-like protein slr1139.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: KATL1_SORAR
Sequence: MNLAEICDNAKKGREYALLGNYDSSMVYYQGVIQQIHRHCQSVRDPAVKGKWQQVRQELLEEYEQVKSIVSTLESFKIDKPPDFPVSYQDEPFRDPAVWPPPVPAEHRAPPQIRRPNREVRPLRKDVAGVGARGPVGRAHPISKSEKPSTNKDKDYRARGRDDKGRKNMQDGASDGDILKFDGAGYDKDLVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRTDLLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFDLALKKIAKSVSDADLEKYEKWMTEFGSA
What is the function of this protein?
Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility.  Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity).  Has microtubule-severing activity in vitro (By similarity).
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A-like 1, Katanin p60 subunit A-like 1, p60 katanin-like 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (By similarity).
Protein: LIMS4_HUMAN
Sequence: MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEERT
What are the official names of this protein?
LIM and senescent cell antigen-like-containing domain protein 4, LIM and senescent cell antigen-like-containing domain protein 3-like.
Protein: VPB46_MYCTU
Sequence: MTPTACATVSTMTSVGVRALRQRASELLRRVEAGETIEITDRGRPVALLSPLPQGGPYEQLLASGEIERATLDVVDLPEPLDLDAGVELPSVTLARLREHER
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in M. smegmatis neutralizes the effect of cognate toxin VapC46.
What are the official names of this protein?
Antitoxin VapB46.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: PPDA_CLOPE
Sequence: MLLLKASAICGKGNEGKRNKKGGFTLIELTVVLAIMAIILMVIAPNFSYVKDSAKAKVDKQNCAAIERSVEMLLAEDAISSSVTNIKITSSNGNVQISGISDDTGKSKLQDLLEDLDKPQSGDSYNVDIENGRKVTVSIV
What is the function of this protein?
Not yet known.
What are the official names of this protein?
Prepilin peptidase-dependent protein A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MP44_YLDV
Sequence: MIVLSNGVRIFINSNMNKDIYLGIASFGFENDIGEILGIAHLLEHILISFDSSKFVANASTARKYMSFWCCSIKGKSNYIDSINTLISWFFNNNKLRDNFCLNDIKNHIKELENEYYFRNEVFHCMDVLTFLENGDLYNGGRIDMLNNLESVNNMLYNRMHKIIGPNIVIFVKELNKNCLMLIQNSFGTLPSCPMSFSFPNFSNIDGKIIMMPSPFYTVMIKVSLSISNVISIMCLFETYHLIDYETVGNDLYVTLSFVKESDYENFINGVSTLKFNNVPNYTVLSLCDDFLMNAYLCFPWLSNDINNYLSTVRYSQNMFKNLEEDIQNSILLKKYIVVYPHFSKTVFNKNDSQMHKIVILDCLNEIKEDQLPKLNVNLMKKQTKNEIFIKYNDSSLIKYIIFAIGYKNNILRGNEGVSIHHQFSSEDIKSILESDTFLKYSKSKPAAMYQYLLLSFFVSGYSIEDILLNRESTIKLLKQYNNKILFGKKSRYDITTKSNFVCGIIKNKNINNNVITNTMWELKKKGLIYSMEHTKIDKRIFYIFMFTIYPDEVFLYLSKKFLSHCLIVSKTGNIEDFSSMKKDVIIKLC
What is the function of this protein?
Seems to be involved in viral proteins maturation by cleavage at Ala-Gly-|-Xaa motifs.
What are the official names of this protein?
Probable metalloendopeptidase G1-type.
What is the protein family that this protein belongs to?
Belongs to the peptidase M44 family.
Protein: FABZ_THIDA
Sequence: MDIEQVMQYLPHRYPFLLVDKVTELELGKRITAVKNVTINEPFFNGHFPGAPVMPGVLILEAMAQAAGILSFKTKNYSPEQIGIIYFAGIDGARFKKPVKPGDQLVLKAEIVREVRGIWKYTGRAEVDGALVAEAELMATLRDKP
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_SULSY
Sequence: MKKIVFLTNDDGYQSKGLQAIRNRLIEENFRVITVAPDRNMSGTSHSLTFTRPLKIEKIEEDFYYIVDGTPADCVHLGLNVILQNQKPDLLISGINTGPNIGNDVFYSGTVGAAREGTLFCIPSVAFSVGSSKNPNFEDVSKVAVKIVKALLIKNLPKGTFLNVNIPTIPAEKIKGFLLTKQGRGAYKEEIVKYLSPSKEEYYWIGGEEALLEECSPGTDYTAVKDGYVSITPIRLDLTDHKAIDILDKENFISEIVRL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_SALEP
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSNIQTVEQLILNWYKTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYAL_CROAD
Sequence: MYHLWIKCLAAWIFLKRFNGVHVMQAKAPMYPNEPFLVFWNAPTTQCRLRYKVDLDLNTFHIVTNANDSLSGSAVTIFYPTHLGFYPHIDGRGHFFNGIIPQNESLAKHLNKSKSDINRMIPLRTFHGLGVIDWENWRPQWDRNWGSKNVYRNRSIQFARDLHPELSEDEIKRLAKQEYEKAAKSFMRDTLLLAEEMRPYGYWGYYLYPDCQNYNYKTKPDQYTGECPDIEITRNNQLLWLWRDSTALFPNIYLETVLRSSDNALKFVHHRLKESMRIASMARKDYALPVFPYARPFYAYTFEPLTEEDLVNTVGETAAMGAAGIVFWGSMQYASTVDSCRKVKDYIDGPLGRYIVNVTTAAKICSHFLCKKHGRCVRKHSDSNAFLHLFPDSFRILVHGNATEKKVIVKGKLELENLIFLINNFMCQCYQGWKGLYCEKHSIKDIRKI
What is the function of this protein?
Snake venom endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments.  In venom, it is not toxic by itself, but increases the diffusion of other venom proteins by degrading the extracellular matrix.  In addition, it displays antiedematogenic activity (By similarity).
What are the official names of this protein?
Hyaluronidase, Hyaluronoglucosaminidase, Venom spreading factor.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AK1A1_BOVIN
Sequence: MAASCILLHTGQKMPLIGLGTWKSDPGQVKAAIKYALSVGYRHIDCAAIYGNETEIGEALKENVGPGKLVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDSPFPKNADGTIRYDSTHYKETWRALEALVAKGLVRALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARNLEVTAYSPLGSSDRAWRDPEEPVLLKEPVVLALAEKHGRSPAQILLRWQVQRKVSCIPKSVTPSRILENIQVFDFTFSPEEMKQLDALNKNLRFIVPMLTVDGKRVPRDAGHPLYPFNDPY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols.  Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids, with a preference for negatively charged substrates, such as glucuronate and succinic semialdehyde (By similarity).  Plays an important role in ascorbic acid biosynthesis by catalyzing the reduction of D-glucuronic acid and D-glucurono-gamma-lactone (By similarity).  Functions as a detoxifiying enzyme by reducing a range of toxic aldehydes.  Reduces methylglyoxal and 3-deoxyglucosone, which are present at elevated levels under hyperglycemic conditions and are cytotoxic.  Involved also in the detoxification of lipid-derived aldehydes like acrolein (By similarity).  Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs (By similarity).  Displays no reductase activity towards retinoids (By similarity).
What are the official names of this protein?
Aldo-keto reductase family 1 member A1, Alcohol dehydrogenase [NADP(+)], Aldehyde reductase, Glucuronate reductase, Glucuronolactone reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Apical cell membrane.
Protein: REX_STRPN
Sequence: MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLST_BOVIN
Sequence: MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVSWVNRTLNEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGTLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV
What is the function of this protein?
Actin-bundling protein.
What are the official names of this protein?
Plastin-3, T-plastin.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA1_VESCR
Sequence: FNPCPYSDDTVKMIVLTRENKKYDFYTLDTIKNHNEFKDTITLKPHVFITHGFTSSATAENFVVMAKALLDKGNYLVILTDWRMAACTNEIAGLKLAYYPYAASNTRLVGNYIATVTKMLVQKYNVPMANIRLIGHSLGAHISGFAGKKVQELGLGKYPEIIGLDPAGPSFKSNDCSQRICETDANYVQIIHTSNRLGTERTLGTVDFYMNNGYNQPGCGLPIIGETCSHTRAVKYFTECIKHECCLIGVPKSKNPQPVSKCTRNECVCVGLNAKTYPKTGSFYVPVESKAPYCNNKGKII
What is the function of this protein?
Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity).  May act as an allergen and induce hemolytic activity (By similarity).
What are the official names of this protein?
Phospholipase A1, PLA1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PFDB_METKA
Sequence: MAQNVEQQVAQLQQLQQQLSSIVAQKQQLELQLREIERALKELDEIEEDTKVYKTVGGLLIEADRDEVKEELEDRKETLELRVKTLEKQEKRLQQQIENLQKRLQKALQQAEGGGGAGAA
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYAA_PIG
Sequence: MDIAIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGVSEVRSDRDKFVIFLDVKHFSPEDLTVKVQEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVPSGVDAGHSERAIPVSREEKPSSAPTS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: TRUB_RHIME
Sequence: MSRPRKPKGRPISGWLILDKPLDFGSTEAVSKIKWLFKAQKAGHAGTLDPLASGMLPIALGDATKTVPYVMDGRKIYEFTVAWGEERSTDDLEGEAVRSSAARPEEEAIRALLPKYTGVIAQVPPQFSAIKIGGERAYDLARDGETVEIPAREVEVFRLSLIGSAPNLAHFEIECGKGTYVRSLARDMGRDLGCFGHIASLRRTFVAPFGEEDMVPLADLVALEAIEDDAERLAALDAYLIDTGEALSDLPHIAVNDDQAHRLRMGNPIILRGRDAPLPTPEAYATAQGKLVAIGEIAEGEFRPKRVFATQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: PDE1B_RAT
Sequence: MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLEYTASLLEAVYIDETRQILDTEDELRELRSDAVPSEVRDWLASTFTQQTRAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTAVGPTYSTAVHNCLKNLDVWCFDVFSLNRAADDHALRTIVFELLTRHSLISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFRMMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKSKALSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLTDDDSKSKSQPSFQWRQPSLDVDVGDPNPDVVSFRSTWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPSSPAEDEHNQNGNLD
What is the function of this protein?
Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.  Has a preference for cGMP as a substrate.
What are the official names of this protein?
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GCST_SHEFN
Sequence: MASKTVLFNKHLESKAKMVDFHGWEMPINYGSQIEEHHAVRQDAGMFDVSHMTVVDVTGSDACAFLRKLLANDVAKLTVPGKALYGGMLDENAGIIDDLITYYLTDTHYRVVVNSATRDKDLAWINKQAAAFDVVVTERPELAMIAVQGPNAKAKAATVFSAEQNAAVEGMKPFFGVQSASLFIATTGYTGEAGYEIIVPETEAEALWQALLDAGVKPCGLGARDTLRLEAGMNLYGQDMDESINPLAANMGWTVAWEPSERDFIGRDALTAIKAAGTDKLVGLVMEEKGVLRHDMAVFFTDADGVEHQGVITSGSFSPTLGYSIAMARVPSGIGAIAEVEMRKKRVNVKVIAPSFVRNGKQAF
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: UPP1_MOUSE
Sequence: MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA
What is the function of this protein?
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:7744869).  The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Uridine phosphorylase 1, UPase 1, UrdPase 1.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: ANGI_MIOTA
Sequence: MVMGLGLFLLVFMLGLGLTSPTLAQDNSRYRDFLSKHYDARPQGRNDRYCDSMMRRQGMTSPCKDINTFIHGNRRSIRAICGDENGNPYGENLRISRTPFQVTTCNLRGGSPRPPCRYRATAGFRNIVVACENGLPVHLDQSIFRP
What is the function of this protein?
Ribonuclease that cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs).  Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus.  Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA.  Angiogenin induces vascularization of normal and malignant tissues.  Angiogenic activity is regulated by interaction with RNH1 in vivo.
What are the official names of this protein?
Angiogenin, Ribonuclease 5, RNase 5.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).
Protein: SYGB_SULSY
Sequence: MKSYLLEIGCEELPPKAILTYKEFLKEYAHQTFKDFFIYNSPENIKIYATPRRLAVLIKNLKKKQDNQKITLIGPPYKVAVDSEGKFTKAALSFAEKNNIPLEKLEKITTEKGEYLGATIEKEGESLELFIKHKIPQLFNQFPQLKSMKWNNSDYRFPRPIRWIVSLLDDKVIEFEVASVKTDRFTHLHRFMTKPIGRGERKDINHANDYEEITKLGYIIANFEDRKHSIKTQYEGFARQLNASIIEDDELIDEITCLTEFPVGIVGDFSPEYLTLPKEVIITVCKHHQRYLNFEKDGKLIPKFLAFSNNAVKDRDIVKNGYEKVLRARLEDALFFYKEDLKKKLDDNIEKLKGIQFHEKLGSMYDKVLRNLELALKLADLTGYKDAEKIKRAVMLSKADLLTEMVKEFDELQGIMGMYYSQKQGEEEEISKSIYEHYLPKTAEDNIPETNLGTLLALADKLDTVISFIKIGELPKPSADPFGIRRNAIGIVRLLVEKEIDLDLRKVIDDESILDFILSRLESYLQSKGYKTDIINAVLSLKDGNIYRNYLKVKALSQLRNLPDYENVIMVFKRVGNIIPEDFKFSNVDVNLLVSQPEKELYKKFIEIKDKFKRFIENKDYDKALGLLLELKPYIDRFFDNVMIMVEDEKLKNNRLSLLKEINDLFRNIADFTKLIGG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_STAAM
Sequence: MKQGIHPEYHQVIFLDTTTNFKFLSGSTKTSSEMMEWEDGKEYPVIRLDISSDSHPFYTGRQKFAAADGRVERFNKKFGLKSNN
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: IF3_XANP2
Sequence: MRPVAPEKDGPRVNEEIRIREVQLIDQDGQNRGVVAIRDALTLAQEAGLDLVEISPNSAPPVCKILDYGRFKYQNQKKASEARKKQKVVEVKEIKLRPGIDTHDYEVKMRSMERFFEEGDKVKVTLRFRGREMAHQDIGFKLLQKLKEDVAAIAKVEAEPMLEGRQMIMILSPR
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_YERPA
Sequence: MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHLSCVSNDFGYDYVFSRYVEAVGREGDVLLGISTSGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.