PharMolix/UniProtQA huggingface dataset:
Protein: UGPE_ECOK1
Sequence: MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQEVYAAPMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWPLLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGLVDSEK
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpE.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS14Z_CLOPE
Sequence: MARKAMIEKWKKEPKYKTRAYTRCRLCGRPHSVLKKFGICRICFRELAYKGEIPGCRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: MB43_EHV4
Sequence: IHATAHAVCVVLAAFGYWVAAPISLAFTTSGGVLGALYLRKRATGASRLAATHISRWLIVSVYVAAGLCYATIITH
What are the official names of this protein?
Membrane protein UL43 homolog, Membrane protein ORF1.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL43 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MURQ_CLOBH
Sequence: MTNISLDKLVTESRNENTKNIDRVETLEMLKMINNEDKKVAEAVEKELIHIAKAVDKIGEAFLNGGRLIYVGAGTSGRLGVLDASECPPTYGVSYDLVRGIIAGGESAMFKAREGAEDSKKLCIKDLKNINFGKNDILAGIAASGRTPYVIGGLEYANGIGATTISVTCNPESEMSKIANISIAPVVGPEAITGSTRMKAGTAQKMVLNMLSTGAMVKTGKVYGNLMVDLKATNEKLVERAKRIVMQATGSKREQVEKILKETNFDVKLSIFMIESSLDKIKAKEILDKNKGYIVEAIKEIS
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: SUFS_BACSU
Sequence: MNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLDAEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTKEYFTNVF
What is the function of this protein?
Type II cysteine desulfurase that acts as the initial step in the SUF-like Fe-S cluster assembly pathway.  Catalyzes the removal of elemental sulfur atoms from L-cysteine by using the cofactor pyridoxal 5'-phosphate (PLP), resulting in the production of L-alanine and persulfide (PubMed:31587510).  Activity is stimulated by SufU, which acts as a sulfurtransferase that receives sulfur from SufS via a zinc-ligand swapping mechanism and transfers it to SufB (PubMed:29235855, PubMed:27382962).
What are the official names of this protein?
Cysteine desulfurase SufS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: CIN_BPP7
Sequence: MLIGYVRVSTNEQNTALQRNALESAGCELIFEDKASGKQTERPGLKKVLRMLSRGDTLVVWKLDRLGRSMRHLVVLVEELRDRGINFRSLTDSIDTSTPMGRFFFHVMGALAEMERELIVERTRAGLDAARAEGRIGGRRPKYQEETWQQMRRLLENGIPRKQVAIIYDVAVSTLYKKFPASSFQS
What is the function of this protein?
Performs inversion of a viral 3 kp segment (C-segment) that encodes two alternate pairs of tail fiber proteins thereby modifying the host specificity of the virus.
What are the official names of this protein?
DNA-invertase, Site-specific recombinase.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: CAPSB_BPT3
Sequence: MANIQGGQQIGTNQGKGQSAADKLALFLKVFGGEVLTAFARTSVTMPRHMLRSIASGKSAQFPVIGRTKAAYLKPGENLDDKRKDIKHTEKVIHIDGLLTADVLIYDIEDAMNHYDVRAEYTAQLGESLAMAADGAVLAELAGLVNLPDGSNENIEGLGKPTVLTLVKPTTGSLTDPVELGKAIIAQLTIARASLTKNYVPAADRTFYTTPDNYSAILAALMPNAANYQALLDPERGTIRNVMGFEVVEVPHLTAGGAGDTREDAPADQKHAFPATSSTTVKVALDNVVGLFQHRSAVGTVKLKDLALERARRANYQADQIIAKYAMGHGGLRPEAAGAIVLPKGVGVIPDPTGVTLSQKTMTLVEGASRALTGTVQPSDANQSLSWSSSAEDVAVWEAGKVVAKGVGTADITATTSNGLIASCKVIVNAATS
What is the function of this protein?
Assembles with the major capsid protein to form an icosahedral capsid with a T=7 symmetry, about 60 nm in diameter, and consisting of 415 capsid proteins.  The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively.  Once the capsid is formed, encapsidates one single copy of the viral genome.
What are the official names of this protein?
Minor capsid protein, Gene product 10B, Gp10B, Minor head protein.
What is the protein family that this protein belongs to?
Belongs to the T7virus minor capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ARX1_SCHPO
Sequence: MELDPSDSNSRVVDASQFSKYRDAGALVSKAFHQVASRCVPGASTREISSYGDNLLHEYKSSIYKSQRFEKGIAEPTSICVNNCAYNYAPGPESVIAGNDNSYHLQVGDVTKISMGLHFDGYTALISHTIVVTPPPQPGMGPYIGPGADAICAAHYASKAVANLLATNNSDDPITGSRLRKIVDDIASQFRVSVCPGSRIRRISRFLVGQPTIDRLEEDQNTKHAVEWPAPEEETRKADVTNSLDPANVLSTELNTWHVMPKEAWLIDISMSSQPISSLKEHPDLKPTLYIHDVNVSYMLKLKASRSLLSEIKKEKSVFPFHFGSLSSERNLLGLRELTDRHILVPMPVLISSPSNVIAREELTVITQPNPSSDLLCLTVPTPPSYVKSDFSLEDGTDAALICEGINVNIKSININV
What is the function of this protein?
Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.  Accompanies the pre-60S particles to the cytoplasm (By similarity).
What are the official names of this protein?
Probable metalloprotease arx1, Associated with ribosomal export complex protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL16_HAEIE
Sequence: MLQPKRTKFRKVHKGRNRGIASGTEVSFGTYGLKAVGRCRLTARQIEAARRAMSRAVKRQGKIWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLYEMDGVSEEVARNAFALAAAKLPVKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL24_CHLMU
Sequence: MKRRSVCVGDTVYVLAGNDKGKQGKVLRCLKDKVVVEGINVRVKNIKRSQENPKGKRINIEAPLHISNVRLSIDNQPARLFVKVTEKGRELWNKHSDGSSSLYRLVRERKG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ARAG_ECOL6
Sequence: MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGAGKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAENIYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALARNAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKDGRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPISLAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMMLCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPGAEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGVAVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LSM8_HUMAN
Sequence: MTSALENYINRTVAVITSDGRMIVGTLKGFDQTINLILDESHERVFSSSQGVEQVVLGLYIVRGDNVAVIGEIDEETDSALDLGNIRAEPLNSVAH
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166).  The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm8.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHRYS_TANCI
Sequence: MACSSSLSSKWASWGASSRPHPSVQPFVTRKNVVRYHKPTSELSYSPLTTTLSSNLDSQFMQVYETLKSELIHDPSFEFDDDSRQWVERMIDYNVPGGKMVRGYSVVDSYQLLKGEELTEDEAFLACALGWCTEWLQAFILVLDDIMDGSHTRRGQPCWFRLPEVGVVAINDGVLLRNHVHRILKKYFQGKPYYVHLLDLFNETEFQTISGQMIDTICRLAGQKDLSKYTMTLNRRIVQYKGSYYSCYLPIACALLMFGENLEDHVQVKDILVELGMYYQIQNDYLDTFGDPDVFGKTGTDIEECKCSWLIAKALELANEEQKKILSENYGINDPSKVAKVKELYHALDLKGAYEDYETNLYETSMTSIKAHPNIAVQAVLKSCLEKMYKGHK
What is the function of this protein?
Component of the monoterpenoid pyrethrins biosynthesis; pyrethrins are widely used plant-derived pesticide (PubMed:30468448).  Catalyzes the condensation of two molecules of dimethylallyl diphosphate to produce chrysanthemyl diphosphate (CPP), a monoterpene with a non-head-to-tail or irregular c1'-2-3 linkage between isoprenoid units (PubMed:11287653, PubMed:25378387).  In a second step, hydrolyzes the diphosphate moiety of CPP to form chrysanthemol (PubMed:25378387).  With a lower efficiency, can also converts dimethylallyl diphosphate into lavandulyl diphosphate (LPP), and subsequently LPP into lavandulol (PubMed:25378387).
What are the official names of this protein?
Bifunctional chrysanthemol synthase, chloroplastic, Chrysanthemol synthase, chloroplastic, Chrysanthemyl diphosphate synthase, chloroplastic, CPPase, TcCDS.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACCD_FUSNN
Sequence: MSILKNLAKNLGLTNITQPKKKYATVGEKKSDEEKERAKYKVKNIDNLKEDEVTKCPSCGVLSHKSEIRANMKMCSNCNHYFNMSARERIELLIDEGTFKEEDVTLTSANPINFPEYVEKIEKAQHDSGMNEGVISGLGEINGLKVSIACMDFNFMGGSMGSVVGEKITAALERAIEHKIPAVVVAISGGARMQEGLTSLMQMAKTSAAVKKMRLAGLPFISVPVNPTTGGVTASFAMLGDIIISEPKARIGFAGPRVIEQTIRQKLPENFQKSEFLQECGMVDVIAKREDLKATIFKVLNDII
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBXN1_XENTR
Sequence: MAECSTLESLIEMGFSPSRAEKALAATGNQGIEPAMDWLVEHEDDPDIDEPSVVVPEDSDSGTTDTQGMDTCEERLPLTEEEKEKQTKRMMELIAQKQKEREEREKRERIEQEKQRRKQGQELSAVKQKIQEQEMQKAVEDRRREKQEEKLARDRVREKIARDKAERARRFGGAGSEPISPPAEASIPATTPSPSSPVQEPPTKKEYDQCRIQVRLLDGSALSQTFRAREQLAAVRLYVELNWPGGAPGPFNLLTSFPRRVFTEEDMEKPLQELGLVPSAVLIVARK
What is the function of this protein?
Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.  Involved in ubiquitin-proteasome systems (By similarity).
What are the official names of this protein?
UBX domain-containing protein 1, SAPK substrate protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_STRZJ
Sequence: MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGERAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAVVEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFDEIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMA_SHIFL
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLASQILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL6_SYNPW
Sequence: MSRIGKSPIPIPDKVSVSLDGLAVTVKGPKGELKRTLPDGVTVNQVDNTIVVAPTSEKRQSRERHGLCRTLVANMIEGVSKGYSKKLEIVGVGSRAQVKGKTLVVSAGYSHPVEMLAPEGITFAVENNTNVTVSGTDKELVGNEAAKIRAIRPPEPYKGKGIKYAGERILRKAGKSGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CTSR_BACSU
Sequence: MGHNISDIIEQYLKRVLDQNGKEILEIKRSEIADKFQCVPSQINYVINTRFTSERGYIVESKRGGGGYIRIIKIKMNNEVVLINNIISQINTHLSQAASDDIILRLLEDKVISEREAKMMVSVMDRSVLHIDLPERDELRARMMKAMLTSLKLK
What is the function of this protein?
Controls the expression of the cellular protein quality control genes clpC, clpE and clpP, as well as mcsA and mcsB.  Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA).  After heat shock, CtsR is degraded by the ClpCP and ClpEP proteolytic systems, ensuring the derepression of clpE, clpP and the clpC operon.  CtsR negatively autoregulates its own synthesis.
What are the official names of this protein?
Transcriptional regulator CtsR, Class three stress gene repressor.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: RL23_SYNFM
Sequence: MNEKSYRILKRPLVTEKSTTEKDEHNKLFFEVDRRANKIEIKEAVEQIFKVDVLDVATMNVRGKKKRVGRYFTKRADRKKAMVTIKPGQRVEFFEGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CAN5_RAT
Sequence: MFSCTKAYEYQNYSALKRACLRRKVLFEDPHFPASDDSLYYKGTPGPTVRWKRPFDICDDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWNPEKPDSYAGIFHFNFWRFGEWVDVVVDDRLPTVNNQLIYCHSNSKNEFWCAPVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDLATDEAKRSQLFERVLKVHSRGGLISASIKAMTAADMETRLACGLVKGHAYAVTDVRKVRLGHGLLAFFKSEKLDMIRLRNPWGERVWTGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTYEDMCRYFTDIIKCRLINTSYLSIHKTWEEARLRGAWTRHEDPQQNRSGGCINHKDTFFQNPQYIFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSIYINSRSVFLRTELPEGRYVIIPTTFEPGHTGELLLRVFTDVPSNCRELRLDEPPRTCWSSLCGYPQQVTQVHVLGAAGLKDSSTGANSYVIIKCEGEKVRSAVQRGTSTPEYNVKGIFYRKKLSQPITVQVWNNRVLKDEFLGQVHLKTAPDDLQDLHSLHLQDRSGRQPSDLPGIVAVRVLCSASLTAV
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease.
What are the official names of this protein?
Calpain-5.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
Protein: MURG_BORT9
Sequence: MKAKKRIFFTGGGTGGHVFPGIAIISKLRELDTNIEFFWLGQKDSMEDKIIKEHAYIKFIAIPSGKLRRYFSLQNFTDFFKVIFGIIKSFFIIKKYKPQIIYATGGFVSSPPIIAASLLKVKSITHEMDLDPGLATKINSKFANKIHISFKESTKYFKNKNVLYTGSPIRKEFSNPNPNIIKNLTQDTKKPIISILGGSLGAEILNKLTLNIKNKIDAYFIHQCGRNLDATRENNYLRSQFFNAEEMASIIKFSNIIISRAGSGAIKEFANAGACVIFIPFVKGSRGDQIRNAKLLEEQNACFKIDEENLSESKIINIIKEILENKEKSNILRNNIKEFHNQDSSNLIANLLLKEFGKINAG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MT2_PIG
Sequence: MDPNCSCAAGGSCTCAGSCKCKDCKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-2A, MT-2A, Metallothionein-IIA, MT-IIA.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: IF2A_THEGJ
Sequence: MPRKAREYPEEGEFVVATVKNIHPYGAFLILDEYPGKEGFMHISEVAPTWVKNIRDYVKEGQKVVVKVIRVDPEKGHIDLSLKRVNQQQRKAKLQEYKRAQKAENLLKMAAEKIGKDFETAWREVWVPLEEEYGEVYAAFEDAAQNGIEVLKGLIPDEWLDALKPIIEAYVEIPTVTIDAEFEITVPKPNGIEIIKEALIRARDRANEEKDIDVKFTYQGAPRYRIDITAPDYYKAEEVLESIAEEILRVIKEAGGEATLIRKEKRIRKIKRR
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit alpha, aIF2-alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: SYT_CORJK
Sequence: MSTPEITPAAVTFRVPAGTPAGAAMRELGLPNKGPEAIVCVKETEGESAGQLRDLSWVPQQDVEVAAVPANTDEGRGVIRHSCAHVLAQAVQKEFPGTKLGIGPAIDNGFYYDFQVAEPFTPEDLNKLEKTMKKIIKSGQKFERKAYDDVEQARAEYADEPFKTELIADKGNVDPDSDEATEVGAGELTAYSNVNPRTGEVEWYDLCRGPHVPTTRYIPAFALTRSSAAYWRGDQSKAGLQRIYGTAWESKEALAEYQTMMAEAEKRDHRRLGQELDLFSFPDEIGSGFPVFHPDGGIVRLEMEEHSRKRHIASGYSFVNTPHVTKGDLFQKSGHLDFYADGMFPPMQLDGETDDEGNVTKPAQDYYAKPMNCPMHNLIFASRGRSYRELPLRLFEFGTVYRYEKSGVIHGLTRARGFTQDDAHIYCTEDQLEQELTTVLEFIISLLRDYGLDDFYLELSTKDPNKFVGSDEIWERSTEILERVATKSGLELVPDPAGAAFYGPKISVQARDAIGRTWQMSTVQLDFNLPERFNLEYTAPDGSKQRPIMIHRALFGSIERFFGVLLEHYAGAFPAWLAPHQVVGIPVADEFNEYLENFAADLRAQGIRAEVDTSDDRMQKKIRNHTTGKVPFMLLVGGRDVEANAVSFRFLDGTQVNGVPREDALRIISNWIAERRNDQPSSELIQPLVEV
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD2_DROVI
Sequence: MAPNVSIPVERYEPSNLGVNAILLGPPGSGKGTQAPLLQKKFCVCHLSTGDMLRAEISSGSKLGAELKKVMDEGKLVSDDLVVDMIDSNLDKPECKNGFLLDGFPRTVVQAQKLDTLLDKRRTSLDAVIEFAIDDNLLVRRITGRLIHQASGRSYHEEFAPPKVQMKDDITGEPLIKRSDDNVDALKKRLEAYHKQTKPLVDYYGLRGLHFKVDAAKKASDVFSSIDSIFQRKCYSKIQH
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: GLMU_SHEAM
Sequence: MSLNVVILAAGKGTRMRSDLPKVLHSVAHKPMVQHVIDTARELNADNINLVYGYGGELLKAKLGEQPLNFVLQAEQLGTGHAVAQAIDHINDEDTVLVLYGDVPLTRKETLEALLAARQPDGVAVLTVHLDNPTGYGRMVREGGKVVGIVEQKDASPEQLKINEINSGIMALPGKRLKAWLGRLENNNAQGEFYLTDVIAMAHADGVAIDTAHPANPIETEGANNRVQLAALERAYQARRAEELMLAGANLRDPARIDIRGDVTVGMDVMIDVNVIFEGTVKLGNNVTIGAGAILIDCDIADNADIKPYSIIEGAKLGDSASAGPFARLRPGAELHKDAHIGNFVEMKKAVLGEGSKAGHLAYLGDAEIGKGVNIGAGTITCNYDGANKHLTVIEDNVFVGSDTQLVAPVVIRKGATLGAGSTVTHEVGENELVITRVKQRHIQGWQRPVKKPK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_ZYMMT
Sequence: MSVRTKICGISTPETLLAAVKNGASHIGFVFFEKSPRAVQPEMASMLINRIPDHIDKIGVLVDPDDNLLERVVHAGLTGFQLHGHETPERVAFIRRTFPKVKIWKALPITRSQDLDQTLHYRGLVDRVLYDARTDGALPGGMGKRFDWRLLKDYNHPMAWALSGGLDADNIAQAVAITGAELVDVSSGVETAPGIKDMDKIAQFLQAVRLL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RL13_NATTJ
Sequence: MRTTYMAKPHEVERKWYTIDATNKPLGRLASEIAEILRGKHKPTFTPHVDTGDYVIVLNAEKVLLTGKKRTQKHHYRHSGYPGGLKAINYETLLNTKPEKAIELAVKGMLPKNRLGRKMIKKLKVYAGDEHPHQAQQPEPWEG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.