PharMolix/UniProtQA huggingface dataset:
Protein: HYD2A_PYRFU
Sequence: MIIELDEFTRVEGNGKAEIVIENGEVKDARVKIVEGPRFFEILTLGRDYWDVPDLEARICAICYIAHSVASVRAIEKALGIDVPESVEKLRELALWGEIIESHALHLYLLALPDVFGYPDAISMIPRHGELVKEGLTIKAFGNAIRELIGGREIHGINIKPGGFGRYPSEEELEKIAEHSKSLIKFARRIVGIFASQEAGGAVGEVLMATSDYLWGDELIINGERVQYYEVDEVPVGYSFAKHSYYKGNPVFVGALPRLLLKGESIEGEAARMLEEYRDKLESKYVIYNNLAQAIELLYALERVPQLVEEILSEGIERGNGEISQESGEGVGYVEAPRGVLVHHYRIENGKVVWSNTITPTAFNQRLMELSLLEEAKRLYGSESEENMKKRLEVIVRAFDPCISCSVHFVKL
What is the function of this protein?
Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity.  May play a role in hydrogen cycling during fermentative growth.  Activity exhibited with NAD in addition to NADPH.  The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen.
What are the official names of this protein?
Sulfhydrogenase 2 subunit alpha, Hydrogen dehydrogenase (NAD(P)(+)), Hydrogenase-II subunit alpha, H-II alpha, NADP-reducing hydrogenase subunit ShyA, Sulfhydrogenase II subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALS1_CANAX
Sequence: MLQQFTLLFLYLSIASAKTITGVFDSFNSLTWSNAANYAFKGPGYPTWNAVLGWSLDGTSANPGDTFTLNMPCVFKYTTSQTSVDLTADGVKYATCQFYSGEEFTTFSTLTCTVNDALKSSIKAFGTVTLPIAFNVGGTGSSTDLEDSKCFTAGTNTVTFNDGDKDISIDVEFEKSTVDPSAYLYASRVMPSLNKVTTLFVAPQCENGYTSGTMGFSSSNGDVAIDCSNIHIGITKGLNDWNYPVSSESFSYTKTCTSNGIQIKYQNVPAGYRPFIDAYISATDVNQYTLAYTNDYTCAGSRSQSKPFTLRWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPSPNPTVSTTEYWSQSFATTTTVTAPPGGTDTVIIREPPNHTVTTTEYWSQSFATTTTVTAPPGGTDSVIIREPPNPTVTTTEYWSQSFATTTTVTAPPGGTDSVIIREPPNPTVTTTEYWSQSYATTTTVTAPPGGTDSVIIREPPNHTVTTTEYWSQSYATTTTVTAPPGGTDTVIIREPPNHTVTTTEYWSQSFATTTTVTGPPSGTDTVIIREPPNPTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSYATTTTVTAPPGETDTVLIREPPNHTVTTTEYWSQSYATTTTVTAPPGGTDTVIIREPPNPTVTTTEYWSQSFATTTTVTAPPGGTDTVIIYESMSSSKISTSSNDITSIIPSFSRPHYVNSTTSDLSTFESSSMNTPTSISSDGMLLSSTTLVTESETTTESICSDGKECSRLSSSSGIVTNPDSNESSIVTSTVPTASTMSDSLSSTDGISATSSDNVSKSGVSVTTETSVTTIQTTPNPLSSSVTSLTQLSSIPSVSESESKVTFTSNGDNQSGTHDSQSTSTEIEIVTTSSTKVLPPVVSSNTDLTSEPTNTREQPTTLSTTSNSITEDITTSQPTGDNGDNTSSTNPVPTVATSTLASASEEDNKSGSHESASTSLKPSMGENSGLTTSTEIEATTTSPTEAPSPAVSSGTDVTTEPTDTREQPTTLSTTSKTNSESVATTQATNENGGKSPSTDLTSSLTTGTSASTSANSELVTSGSVTGGAVASASNDQSHSTSVTNSNSIVSNTPQTTLSQQVTSSSPSTNTFIASTYDGSGSIIQHSTWLYGLITLLSLFI
What is the function of this protein?
Major cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation.  Acts as a downstream effector of the EFG1 regulatory pathway.  Required for rapamycin-induced aggregation of C. albicans.  Binds glycans and mediates adherence to endothelial and epithelial cells, thereby playing an important role in the pathogenesis of C. albicans infections.
What are the official names of this protein?
Agglutinin-like protein 1, Adhesin 1.
What is the protein family that this protein belongs to?
Belongs to the ALS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently- linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer. Covers the germ tube as well as the cell surface with the exception of bud scars.
Protein: MRAZ_MYCA1
Sequence: MFLGTYTPKLDDKGRLTLPAKFRDALAGGLMVTKSQDHSLAVYPRAEFEQLARRASKASKSNPDARAFLRNLAAGTDEQHPDAQGRITLSADHRRYASLSKDCVVIGAVDYLEIWDAQAWQDYQQTHEENFSAASDEALGDII
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NLTP_RAPSA
Sequence: ALSCGTVNSNLAACIGYLTQNAPLARGCCTGVTNLNNMAXTTP
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.  This isoform inhibits the hyphal growth of several fungi in vitro.
What are the official names of this protein?
Seed non-specific lipid transfer protein-like, LTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: PEPA3_HUMAN
Sequence: MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA
What is the function of this protein?
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
What are the official names of this protein?
Pepsin A-3, Pepsinogen-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PETN_PARMW
Sequence: MLFTVAWASLAAMFSFSIAMVVWGRNGDGTLNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: KDSA_AGRFC
Sequence: MMSVTNNLKVTAGDGASKVSFCNTERFSLIAGPCQMESRDHAFMIAGVLKELCDSLGIGLVYKSSFDKANRTSLSGKRGIGLDSAMEIFADLKKEFGFPVLSDIHTEEQCAIVSEVVDVLQIPAFLSRQTDLLVAAAKTGRVINVKKGQFLAPWDMKNVLAKLNESGNPNVLLCERGASFGYNTLVSDMRSLPIMASLGAPVIFDATHSVQQPGGQGGSTGGQREFVETLARAAVAVGVAGLFIETHEDPDNAPSDGPNMVHLKDMPKLLEKLLAFDAITKA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUND2_BOVIN
Sequence: METSTQRTGSHLAQTAAARHSASSRGEAARVSSRDELAEMAAASQGNFEGKFESLDLAELAKKQPWWRTLFGQESGPSAEKYSVATQLLIGGVTGWCTGFIFQKVGKLAATAVGGGFFLLQLANHTGYIKVDWQRVEKDMKKAKEQLKIRKSNQIPTEVKSKAEEVVSFVKKNVLVTGGFFGGFLLGMAS
What is the function of this protein?
Binds directly and specifically 1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate) (PIP3) leading to the recruitment of PIP3 to mitochondria and may play a role in the regulation of the platelet activation via AKT/GSK3B/cGMP signaling pathways (By similarity).  May act as transcription factor that regulates SREBP1 (isoform SREBP-1C) expression in order to modulate triglyceride (TG) homeostasis in hepatocytes (By similarity).
What are the official names of this protein?
FUN14 domain-containing protein 2, Hepatitis C virus core-binding protein 6.
What is the protein family that this protein belongs to?
Belongs to the FUN14 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Nucleus.
Protein: SYH_SYNR3
Sequence: MEQLQSLRGMVDLLPAATSRWQWLEQTAREHFRRSCIREIRTPLLEATELFARGIGEATDVVGKEMYSFNDRGDRSCTLRPEGTASVVRAAIQHGLLSQGAQRLWYGGPMFRYERPQGGRQRQFHQIGIEFLGFADPRSDVEAIAIAWDLLEALGITGLQLELNSLGSRVDRQTYRDALVGWLSERQNQLDADSQQRLATNPLRILDSKNPQTQQLLQDAPNLEQSLSDPSRERYEQVKAGLSALKIPYLCNPRLVRGLDYYGHTAFEITSDALGAQATVCGGGRYDGLVEQLGGPAAACVGWAMGLERLMLLLGDESQQSQPPDVVVISQGNAAEALAVPVARQLRQIGQAVDVDLSGAGFGKQLKRAGKSGARWAVLIGDEEASSGQLQRKDLHSGDSSTIALQSLAENWIS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPA7_SHIFL
Sequence: MFSVNNTHSSVSCSPSINSNSTSNEHYLRILTEWEKNSSPGEERGIAFNRLSQCFQNQEAVLNLSDLNLTSLPELPKHISALIVENNKLTSLPKLPAFLKELNADNNRLSVIPELPESLTTLSVRSNQLENLPVLPNHLTSLFVENNRLYNLPALPEKLKFLHVYYNRLTTLPDLPDKLEILCAQRNNLVTFPQFSDRNNIRQKEYYFHFNQITTLPESFSQLDSSYRINISGNPLSTRVLQSLQRLTSSPDYHGPQIYFSMSDGQQNTLHRPLADAVTAWFPENKQSDVSQIWHAFEHEEHANTFSAFLDRLSDTVSARNTSGFREQVAAWLEKLSASAELRQQSFAVAADATESCEDRVALTWNNLRKTLLVHQASEGLFDNDTGALLSLGREMFRLEILEDIARDKVRTLHFVDEIEVYLAFQTMLAEKLQLSTAVKEMRFYGVSGVTANDLRTAEAMVRSREENEFTDWFSLWGPWHAVLKRTEADRWAQAEEQKYEMLENEYSQRVADRLKASGLSGDADAEREAGAQVMRETEQQIYRQLTDEVLALRLSENGSRLHHS
What is the function of this protein?
E3 ubiquitin ligase effector protein that interferes with host's innate immunity (PubMed:30872533, PubMed:34022140, PubMed:34492225).  Functions to alter host cell physiology and promote bacterial survival in host tissues (PubMed:30872533, PubMed:34022140, PubMed:34492225).  Catalyzes ubiquitination of host gasdermins GSDMB and GSDMD, promoting their degradation by the proteasome, thereby preventing cell death (PubMed:34022140, PubMed:34492225).  In contrast, activates host cell pyroptosis in mouse cells: catalyzes ubiquitination of mouse Nlrp1b allele 1 protein, releasing the cleaved C-terminal part of Nlrp1b, which polymerizes and forms the Nlrp1b inflammasome followed by host cell pyroptosis (PubMed:30872533).
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase ipaH7.8, Probable RING-type E3 ubiquitin transferase ipaH7.8.
What is the protein family that this protein belongs to?
Belongs to the LRR-containing bacterial E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cytoplasm.
Protein: CDK16_MOUSE
Sequence: MDRMKKIKRQLSMTLRGGRGIDKTNGVPEQIGLDESGGGGGSDLGEAPTRIAPGELRSVRGPLSSAPEIVHEDMKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFRTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDARKHPFFLSLGERIHKLPDTTSIFALKEVQLQKEANIRSTSMPDSGRPAFRVVDTEF
What is the function of this protein?
Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis.  Can phosphorylate CCNY at 'Ser-336' (in vitro) (By similarity).  Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels.  Regulates GH1 release by brain neurons.  Phosphorylates NSF, and thereby regulates NSF oligomerization.  Required for normal spermatogenesis.  Regulates neuron differentiation and dendrite development.
What are the official names of this protein?
Cyclin-dependent kinase 16, CRK5, Cell division protein kinase 16, PCTAIRE-motif protein kinase 1, Serine/threonine-protein kinase PCTAIRE-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Synapse, synaptosome. Note=Colocalizes with insulin in pancreas islets.
Protein: FOLD_SHEPC
Sequence: MTAQIIDGKAIAQSIRTKLSEKVTARKEAGQRVPGLAVILVGADPASQVYVGSKRKACEEVGFISRSYDLETNCTEDELLNLIDSLNDDPTIDGILVQLPLPAHIEDSKVIERIRPDKDVDGFHPYNVGRLAQRIPVLRSCTPMGIMTLIKSTGVDTYGLDAVVVGASNIVGRPMTLELLLAGCTTTTCHRFTKNLEQKIRQADLVVVAVGKPGFIPGEWIKPGAIVIDVGINRLDNGTLVGDVQYEAAAQNASFITPVPGGVGPMTIASLLENTLYAAEQYHD
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y320_SHEB2
Sequence: MTKKIELAQIRVLFLGIWHFLLHLRRRLVEDQINIRAGHLAYVTLLSLVPMVAVTMSMLSAFPVFKGIRGQIEGFVYENFLPAAGDTVQVYINEFVGNASKGTAVGISALVVVAIMLISAIDKSLNNIWRTKEKRSVVVAFSMYWMVLTLGPVLVGASLVASSYVISLKVFEAEALSGMLPIFIARLPMLFSVAAFLLLYMVVPNQKVKFLHALLGAIVAALLFELGKKGFALYVTQFPSYEAIYGALATIPIVFVWVYLSWMIVLLGAEITAAMPEYLDYESSSDDETALNAKPLADASQGDSSSVLTSAEVTALKAVAKSE
What are the official names of this protein?
UPF0761 membrane protein Sbal223_0320.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLD1_RHOBA
Sequence: MLVVSELSKSYPTAGEPLSVLRGVNLELSPGQSAAIVGPSGSGKTTLLQILGTLDEPDSGSVQINGQDPFALDARERAAYRNQTIGFIFQDHHLLPQLSVTENVLIPALANGKPTSDDVSRAAELIDAVGLSHRATHLPRELSGGERERVAIARALLMQPSVVLADEPTGNLDSKTAKTITELLLRLQAEQNTVLVTVTHSLSLADEMNERFELVDGALVRRGRFGITA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PPOA_EMEND
Sequence: MGEDKETNILAGLGNTISQVENVVAASLRPLPTATGDGTYVAESTQTGLAKDLSHVDLKDVRTLAEVVKSAATGEPVDDKQYIMERVIQLAAGLPSTSRNAAELTKSFLNMLWNDLEHPPVSYLGADSMHRKADGSGNNRFWPQLGAAGSAYARSVRPKTMQSPSLPDPETIFDCLLRRKEYREHPNKISSVLFYLASIIIHDLFQTDPKDNSVSKTSSYLDLSPLYGNNQDEQNLVRTFKDGKLKPDCFATKRVLGFPPGVGVLLIMFNRFHNYVVDQLAAINECGRFTKPDESNVDEYAKYDNNLFQTGRLVTCGLYANIILKDYVRTILNINRTDSTWSLDPRMEMKDGLLGEAAAMATGNQVSAEFNVVYRWHACISKRDEKWTEDFHREIMPGVDPSTLSMQDFVAGLGRWQAGLPQEPLERPFSGLQRKPDGAFNDDDLVNLFEKSVEDCAGAFGASHVPAIFKSVEALGIMQARRWNLGTLNEFRQYFNLAPHKTFEDINSDPYIADQLKRLYDHPDLVEIYPGVVVEEAKDSMVPGSGLCTNFTISRAILSDAVALVRGDRFYTVDYTPKHLTNWAYNEIQPNNAVDQGQVFYKLVLRAFPNHFDGNSIYAHFPLVVPSENEKILKSLGVAEKYSWEKPSRISHPIFISSHAACMSILENQETFKVTWGRKIEFLMQRDKHQYGKDFMLSGDRPPNAASRKMMGSALYRDEWEAEVKNFYEQTTLKLLHKNSYKLAGVNQVDIVRDVANLAQVHFCSSVFSLPLKTDSNPRGIFAESELYKIMAAVFTAIFYDADIGKSFELNQAARTVTQQLGQLTMANVEIIAKTGLIANLVNRLHRRDVLSEYGIHMIQRLLDSGLPATEIVWTHILPTAGGMVANQAQLFSQCLDYYLSEEGSGHLPEINRLAKENTPEADELLTRYFMEGARLRSSVALPRVAAQPTVVEDNGEKLTIKAGQVVMCNLVSACMDPTAFPDPEKVKLDRDMNLYAHFGFGPHKCLGLDLCKTGLSTMLKVLGRLDNLRRAPGAQGQLKKLSGPGGIAKYMNEDQSGFTPFPSTMKIQWDGELPQLKEDF
What is the function of this protein?
Bifunctional heme-containing enzyme that oxidizes linoleic acid to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate (within the N-terminal heme peroxidase domain), which is subsequently isomerized to (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate (within the C-terminal P450 heme thiolate domain).  Oxidized unsaturated fatty acids, so-called oxylipins, derived from endogenous fatty acids, influence the development of the asexual conidiophores and sexual cleistothecia and regulate the secondary metabolism.  These substances were collectively named psi factors and are primarily a mixture of hydroxylated oleic, linoleic and alpha-linolenic acids.  They are termed psi-beta, psi-alpha, and psi-gamma, respectively.
What are the official names of this protein?
Psi-producing oxygenase A, Fatty acid oxygenase ppoA.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family.
Protein: CMOM_ECOLI
Sequence: MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV
What is the function of this protein?
Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.  Four tRNAs (tRNA(Ala1), tRNA(Ser1), tRNA(Pro3) and tRNA(Thr4)) are fully modified with mcmo5U in stationary-phase E. coli.  Also present at low frequency in tRNA(Leu3) and tRNA(Val1).
What are the official names of this protein?
tRNA 5-carboxymethoxyuridine methyltransferase, cmo5U methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
Protein: YH070_YEAST
Sequence: MTHRAVPCQPRAFSKIKVLVISFLFLMVAFLPFSSHGKLQEQIASYVSWKLETRAIHRFGGCNFAHQMQRNGIQRKIVCSDLERGNNTGMNACMQLVLSDLVARRVLLKTVHVHPWHLDGISGAFSVCCKDATEVS
What are the official names of this protein?
Putative uncharacterized protein YHR070C-A.
Protein: QUEC_MAGMM
Sequence: MPTIMSAVVLLSGGLDSATVLRMAHATGQRIHALSFRYGQRHTMELEMARKQALSLPGVAHRIMDLQLSLFGGSALTADIPVPKGGVDENTIPVTYVPARNMVFLSLALAWAESLGAQHLYIGVNAVDYSGYPDCRPEFIQSFQQTANLATKAGVEGHPFTVHTPLINLTKAQIIQQGLALGVDYGLTRSCYDPDAQGAGCGLCDACRLRLQGFAEAGVPDPAPYQGP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PSTB2_STRA3
Sequence: MAEYNWDERHIITFPEENSALTTKDLHVYYGEKEAIKGIDMQFEKNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGQIMYEGIDVNAQDINVYEMRKHIGMVFQRPNPFAKSIYKNITFAYERAGVKDKKFLDEVVETSLKQAALWDQVKDDLHKSAFTLSGGQQQRLCIARAIAVKPEILLMDEPASALDPIATMQLEETMFELKKNYTIIIVTHNMQQAARASDYTAFFYLGDLIEYDKTNNIFQNAKCQSTSDYVSGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: WHIA_CLAMS
Sequence: MPLTSDVKEELSRVEVSKTTVRAAELATILRFSGGLHLISNRIAVESELDTPLLARRVRKDLAELYGVRSDISVIPASGMRRATHYLVRVMEGGETLARQTGLLDARRRPIRGLPNRLTTGSREEIAAVWRGAFLAAGTLTDPGRSAALEVTCPGNEAAMALVGAAGRLDVSAKAREVRGVHRVVIRDGDAIGQMLRAMGAQGTVVNWEEMRQRREVRATANRLVNFDDANLRRSAQAAVAACARVERAMEILGPDIPEHLKYAGDLRLRFRDSSLDELGHHADPPMTKDAVAGRIRRLLAMADKKAVDEGLPGTDANLPADLDDV
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: FTSH_STRPN
Sequence: MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYTELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTILPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGGGNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGRVAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKSISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYETGKMPEAVEEESHALSYDEVKSKMNDEK
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: Y811_STAES
Sequence: MSNQSKLNSAAYDQLNKDADRILHLIKVQMDNLTLPSCPLYEEVLDTQMFGLQKEVDFAVQLGLVDKEDGKQLMLRLEKELSKLHEAFTNV
What are the official names of this protein?
UPF0358 protein SE_0811.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: LARP7_RAT
Sequence: METENQKTMEESTEKRKEEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLIARALKSSSVVELDLEGTRIRRKKPLGERPKDEEERTVYVELLPKNVTHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPSLRVAEEKKKKKKKKGRIKKEESVQAKELVVDSSSSGVSKATKRPRTASEGSEAETPEAPKQPAKKKKKRDKVETGGLPESKAGKRERSSAEDEDCLPPRPKLKKRAQKDGGGPAASEVSKEHRDLEFCSTEEEKEPGDRKGDSLSKGKRKHKKKHKERHKMGEEVIPLRVLSKTEWMDLKKEYLALQKASMASLKKTISQIKLESEMETESKAPPGSGQQCSTQEKVSAQGPQFVTGVIVKILSEDPLPGRKQVKDILATISEVVYIDLLEGDTECHARFKTPEDAQAVMNAQTEIKKKHSWNLEILSGDHEQRYWQKILVDRQAKLNQPREKKRGTEKLITKAEKIRLAKTQQASQHIRFSEYD
What is the function of this protein?
RNA-binding protein that specifically binds distinct small nuclear RNA (snRNAs) and regulates their processing and function.  Specifically binds the 7SK snRNA (7SK RNA) and acts as a core component of the 7SK ribonucleoprotein (RNP) complex, thereby acting as a negative regulator of transcription elongation by RNA polymerase II.  The 7SK RNP complex sequesters the positive transcription elongation factor b (P-TEFb) in a large inactive 7SK RNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.  The 7SK RNP complex also promotes snRNA gene transcription by RNA polymerase II via interaction with the little elongation complex (LEC).  LARP7 specifically binds to the highly conserved 3'-terminal U-rich stretch of 7SK RNA; on stimulation, remains associated with 7SK RNA, whereas P-TEFb is released from the complex.  LARP7 also acts as a regulator of mRNA splicing fidelity by promoting U6 snRNA processing.  Specifically binds U6 snRNAs and associates with a subset of box C/D RNP complexes: promotes U6 snRNA 2'-O-methylation by facilitating U6 snRNA loading into box C/D RNP complexes.  U6 snRNA 2'-O-methylation is required for mRNA splicing fidelity.  Binds U6 snRNAs with a 5'-CAGGG-3' sequence motif (By similarity).  U6 snRNA processing is required for spermatogenesis (By similarity).
What are the official names of this protein?
La-related protein 7, La ribonucleoprotein domain family member 7.
What is the protein family that this protein belongs to?
Belongs to the LARP7 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: RS10_NEIG1
Sequence: MANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPTKIERFNILRSPHVNKTSREQLEIRTHLRLMDIVDWTDKTTDALMKLDLPAGVDVEIKVQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RPP1_YEAST
Sequence: MLVDLNVPWPQNSYADKVTSQAVNNLIKTLSTLHMLGYTHIAINFTVNHSEKFPNDVKLLNPIDIKRRFGELMDRTGLKLYSRITLIIDDPSKGQSLSKISQAFDIVAALPISEKGLTLSTTNLDIDLLTFQYGSRLPTFLKHKSICSCVNRGVKLEIVYGYALRDVQARRQFVSNVRSVIRSSRSRGIVIGSGAMSPLECRNILGVTSLIKNLGLPSDRCSKAMGDLASLVLLNGRLRNKSHKQTIVTGGGSGNGDDVVNDVQGIDDVQTIKVVKRSMDAEQLGHASKRHKP
What is the function of this protein?
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.  Also a component of RNase MRP, which cleaves pre-rRNA sequences.
What are the official names of this protein?
Ribonuclease P/MRP protein subunit RPP1, RNA-processing protein RPP1, RNaseP/MRP 32.2 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Nucleus.