PharMolix/UniProtQA huggingface dataset:
Protein: PXR1_NEUCR
Sequence: MGLAAAKNKRKLGTDPNNTKWSRNETTFGQKILRAQGWQPGEFLGAKDAAHAVHHTEASSSHIKVTLKDDNLGLGAKRNNGDECTGLFDFQHLLGRLNGKSEDVLEAEKQKRENHIRNHYLEQKIGTIRFVRGGWLVGDVVKEKVTEEDGVPQSDTVDQQVETVPSQDTKDAEPTKRKSKKRKADSDEEDEKEEKKDKKVKKRKTDTEAETDSESSRSKKKEKKDKKEKKDQKEKKDKKDKRKLKDAKQSEESSSDDLESSATETKKSKKDKKKEKKEKKDKKKDKKEKKRKEKELSDSATESEDSKSKAQKRTKDGAEIETSTPGGSGTSTPTVTSSTRFLARQRFIAQKKMAFTDSAALNQIFMIKS
What is the function of this protein?
Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.
What are the official names of this protein?
Protein pxr-1, PinX1-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the PINX1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: EX7L_STRA5
Sequence: MSDYLSVSTLTKYLKLKFDKDPYLERVYLTGQVSNFRRRPNHQYFSLKDDKSVIQATMWSGHFKKLGFELEEGMKVNVVGRVQLYEPSGSYSIIVEKAEPDGIGALAIQFEQLKKKLSQAGYFDDRHKQLIPQFVRKIGVVTSPSGAVIRDIITTVSRRFPGVEILLFPTKVQGEGAAQEIAQTIALANEKKDLDLLIVGRGGGSIEDLWAFNEECVVEAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPVTKIDILSWITERENRMYQSSLRLIRTKEERLQKSKQSVIFRQPERLYDGFLQKLDNLNQQLTYSMRDKLQTVRQKQGLLHQKLQGIDLKQRIHIYQERVVQSRRLLSSTMTSQYDSKLARFEKAQDALISLDSSRIVARGYAIIEKNHTLVSTTNGINEGDHLQVKMQDGLLEVEVKDVRQENI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDH11_ARATH
Sequence: MGVCCPFLQPWDRARDQCLLNLPCLSDPVRRSSLLLKLALVALHLVFIGFLFLFDAEFIEKTKRDPWYMGCYILLFSATLLQYFVTSGSSPGYVVDAMRDVCEASAMYRNPSTTSIQHASRKSESVVVNVEGGSASCPRRPPTPWGKLVLDLYPPGTSIRNLTCGYCHVEQPPRTKHCHDCDRCVLQFDHHCVWLGTCIGQKNHSKFWWYICEETTLCIWTLIMYVDYLSNVAKPWWKNAIIILLLVILAISLIFVLLLLIFHSYLILTNQSTYELVRRRRIPYMRNIPGRVHPFSRGIRRNLYNVCCGNYNLDSLPTAFELEDRSRPYTCIDMLKCRCC
What is the function of this protein?
S-acyltransferase involved in protein lipid modification.  Catalyzes the palmitoylation of proteins peripheral or integral to the tonoplast.  Required for the tonoplast localization of CBL2, CBL3 and CBL6, but not for the plasma membrane localization of CBL9, for the endosome localization of RABF1 or for the endomembrane localization of RABF2B.
What are the official names of this protein?
Protein S-acyltransferase 10, Probable palmitoyltransferase At3g51390, Zinc finger DHHC domain-containing protein At3g51390.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Transient expression results in mistargeting of PAT10 to the Golgi apparatus, while the non-functional mutant is also localized in Golgi apparatus membranes.
Protein: ARGB_SINMW
Sequence: MSASESEIQARLLAQALPYMQRYENKTIVVKYGGHAMGNAELGRAFASDVALLKQSGVNPIVVHGGGPQIGAMLNKMGIESKFEGGLRVTDEKTVEIVEMVLAGSINKEIVALINQTGEWAIGLCGKDGNMVFAEKAKKTIRDPDSNIERVLDLGFVGDVVEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALNATRLLFLTDVPGVLNKKGELIKQLSVAEARALIADGTISGGMIPKVETCIEAIGAGVQGVVILNGKTAHAVLLEIFTEHGAGTLIVP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASZ_BORBR
Sequence: MTERIPHHGLQVAASLHRFIEDEALSGSGLAPDEFWAGFAALVRDLAPRNRELLAERDRLQGEIDAWHRAHPGPVRDSAGYQALLERIGYLQPQPAQVTASTRDVDSEIASQAGPQLVVPVSNARYALNAANARWGSLYDALYGTDAIPPVAGDDGKGYNPARGEAVIARARAFLDEAAPLAQGSHADATAYAIEGGKLAVTLGAGQRTGLRNPAQLAGYQGDASQPAAVLLANNGLHFEIQIDRQHQIGATDAAGVKDVLLEAALTTIMDCEDSVAAVDADDKVLIYRNWLGLMKGDLSESVTKGGKTFTRRLNADRQYHKPDGGTLTLHGRSLMFVRNVGHLMTNPAILDEQGNEVPEGILDAVITSLAALPDRANRLNSRTGSIYIVKPKMHGPAEAAFANELFDRVEDLLKLPRHTIKMGIMDEERRTSVNLKACIAAAAARVAFINTGFLDRTGDEMHTGMEAGPMLRKGDMKSSAWITAYERNNVLVGLDCGLRGRAQIGKGMWAMPDMMAAMLEQKIGHPKAGANTAWVPSPTAATLHAMHYHQVDVAAVQQALEQTRYDSVRDELLAGLLTVPVGDPAAWSADDIQRELDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISSQHIANWLRHGIVDRAQVNATFERMAKVVDQQNAGDPNYLPMAGHFDTSFAYRAACALVFEGLTQPNGYTEPLLHEYRQAFKAAQR
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SVIL_BOVIN
Sequence: MKRKERIARRLEGIETDTQPILLQSCTGLVTHRLLEEDTPRYMRATDPASPHIGRSNEEEETSDSSLEKQTRSKQCTETSGIHADSPYSSGIMDTQSLESKAERIARYKAERRRQLAEKYGLTLDPEADSETPSRYSRSRKDPEAAEKRGVRSERSAESSRDAGSSYSRTELSGLRTCVAESKDYGLHRSDGVSDTEVLLNAENQRRGQEPSATGLARDLPLAGEVSSSFSFSGRDSALGEVPRSPKAVHSLPSPSPGQPASPSHSTSDLPLPAEARASIGKPKHEWFLQKDSEGDTPSLINWPSRVKVREKLVREESARSSPELTSESLTQRRHQTAPGHYLAFQSENSAFDRVSGKVASSARQPIRGYVQPAEPVHTITLVTSDTPESISEGSWVGPAPQTVTKPPPSKVLEGERRDTPVLHICESKAEDVLFSDALEKTRKTLAVLEDRGSGRSQEAPSGTEDLSQPAVGIVTAEPQKESESLAHPPMAQQQPTERMGRSEMVMYVQSEAVSQGHRKEVPTRKHRVLTRSLSDYTGPPQLQALKAKAPAPKRDAESQTSKAELELGLLDTKVSVAQLRNAFLESARASRKPELHSRVEGSSEGPGVERERGSRKPRRYFSPGENRKTSERFRTQPITSAERKESDRSTSNSEMPAAEDEEKVDERARLSVAAKRLLFREMEKSFDEKSVPKRRSRNAAVEQRLRRLQDRSHTQPVTTEEVVIAAEPTPASCSVATHPVMTRHPSPTVAKSPVQPARTLQASAHQKALARDQTNESKDSAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRLDMRQRRMNARYQTQPVTLGEVEQVQSGKLMAFSPTINTSVSTVASTVPPMYAGNLRTKPLPDDSFGATEQKFASSLENSDSPVRSILKSQGWQPSVEGAGSKAMLREFEETERKGGLTGGDGGVTKYGSFEEAELSYPVLSRVREGDNHKEAIYALPRKGSLELAHPPIAQLGDDLKEFSTPKSTMQASPDWKERQLFEEKVDLENVTKRKFSLKAAEFGEPTSEQTGAAAGKPAAPTATPVSWKPQDPSEQPQEKRYQSPCAMFAAGEIKAPAVEGSLDSPSKTMSIKERLALLKKSGEEDWRNRLNRKQEYGKASITSSLHIQETEQSLKKKRVTESRESQMTIEERKHLITVREDAWKTRGKGAANDSTQFTVAGRMVKRGLASPTAITPVASPVSSKARGTTPVSRPLEDIEARPDMQLESDLKLDRLETFLRRLNNKVGGMQETVLTVTGKSVKEVMKPDDDETFAKFYRSVDSSLPRSPVELDEDFDVIFDPYAPRLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFVESKRMKVEKLSANSSFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKKLMLLQVKGRRHVQTRLVEPRAPSLNSGDCFLLLSPHHCFLWVGEFANVIEKAKASELASLIQTKRELGCRATYIQTVEEGINTHTHAAKDFWKLLGGQASYQSAGDPKEDELYETAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQSKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRPNEKNASELAQHKDDARAEVKPYDVTRMVPVPQTTAGTVLDGVNVGRGYGLVEGDDRRQFEIASISVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFIVSTAVGSRQKGEHSVRVAGKEKCVYFFWQGRQSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREEEEENTQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVHKALIYLWHGCKAQAHTKEVGRTAANKIKDQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDCMLQDPGNFNFTPRLFILSSSSGDFSATEFMYPARDPSVVNSMPFLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCRGKNLKKPPPKSYLIHAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF
What is the function of this protein?
May be involved in modulation of focal adhesions.  Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6 (PubMed:16880273, PubMed:17925381).  Plays a role in cytokinesis through KIF14 interaction (PubMed:20309963).
What are the official names of this protein?
Supervillin, Archvillin, p205/p250.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, invadopodium. Cell projection, podosome. Midbody. Cleavage furrow. Note=Tightly associated with both actin filaments and plasma membranes.
Protein: RS9_HALHL
Sequence: MANQQYYGTGRRKTSAARVFMTPGNGNITVNGRPLDEYFGRETGRMIVRQALEQVDAGDKFDIKATVSGGGSSGQAGAVRHGIARALANYDAELKAPLRRAGFITRDARMVERKKIGLHKARRATQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: COAE_STAEQ
Sequence: MSKVIGITGGIATGKSTVSELLTAYGFKIVDADIASREAVKKGSKGLEQVKEIFGEEAIDENGEMNRQYVGEIVFNHPDLREALNEIVHPIVREIMEQEKNNYLEHGYHVIMDIPLLYENELQDTVDEVWVVYTSESIQIDRLMERNNLSLEDAKARVYSQISIDKKSRMADHVIDNLGDKLELKQNLQKLLEEEGYIQSESE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8975_DICDI
Sequence: MSESAVPADIIMQPFAKLSEESLKLAVESLNELKIPNTTLASTTAEQQQQQQQQQQPPSSSTTKEGGATTTQDNKLTANGGTTADNNNNKPMVINKLDYLPIIKSNIWDESYGWLTTIPNSESFAQIIGTTIKEGKDIKKTLYILDPKQLKESFNLLGLDQQENSIDTNEMIYKIEEEMMMQGIFKILFKLDKKTLESFCRDLKIQIKDDMGALCDSIMSTMYDLEESPDTTTTAAATTTTTTTTAAVPPPPTTTTTTTTTTPTIASTPTVVPPTNTTTTTSTTSPIPSTTPLTNTTSIAAATTTTTTTPTDNSGTNSPNKETTPSKAKKGVPKKAPTKKQPATKSPTTETAGIVPTTTTTPPQATTTTTTTTPPTNIIAPKTNSTIISPPTEAPSKPAPKTSKSQATTTTTTTTVQSTTKNTEKSQNLTNTEQPKKKLRSSLDKPSSDKPLTPTLPGKRERKPLPLDPVHLQPEQKSKPGSGSAQSASTAKPTPTTTTTTTTTTKPKSTIAKTSTSTTIKSKPTTKKKETTKIITNGKRKRKQDNNNGNEEAAAEEQEEEEEEDNSNGIQNNNSSNDVEINSENESDREQNDNFSNFGSSNGNGNGLLSEDDDDDDDDDNNNNIMDYQSTASSEIKGYYTHDRKWICPSFDYIKKGIERGFLQNNFNLSDLLEYCKIHDLPKNKTKTKTIKIILDFVETGTAPQQTSKPKKLVGKAAAKKKLQDQQELASS
What are the official names of this protein?
Uncharacterized protein DDB_G0290587.
Protein: RL2_PSYIN
Sequence: MAIVKCKPTSPGRRHLVKVVNNDLHKGKPFAALLESKSKSGGRNNGGRITVRHIGGGHKQHYRIVDFKRNKDGIPAKVERLEYDPNRSANIALVLYSDGERRYILAPKGLVAGDQIISGEDASIKVGNCLPMRNIPVGTTVHAVEMKPAKGAQIARSAGAYSQIVARDGAYVTLRLRSGEMRKIPTECRATIGEVGNAEHMLRQLGKAGATRWRGVRPTVRGVVMNPVDHPHGGGEGKSSGGRHPVSPWGMPTKGYKTRKNKGTDQYIVRRRNKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SULA_KLEAE
Sequence: MFTSAHANRSPLTSASVRRPSHSVVEHSATGLISEIVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSKEWVQSSGLPLSKVMQINQMSPCNTLESMIRALRTGNYNVVIGWLTDELTEQEHERLALAAEEGHPMGFIMRPVRNTSQPGRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: YO31_STRGR
Sequence: MRTSTARRTGTALAVAAALTSIAACSGSDGAKGSDGAGEGKAGAVSKASPVAALKQVQQKTGGAQSAKVEGTTEMGSVMSMKQSGAIGWADGLSGALTITYTGGTMGDALKQAGGDGSVQARYFKDEYYANMGDAMAANTGGKHWIRYSYKDLAELGGASGDVMKDQIQNSTPEQGVKALLASGDVKKVGQEDVRGVPATHYSGTVDVAGLTAKNSNLDAEQLAAFKEQLALAGVTTQTVDIWVDKNDLLVKKTERGEMKTGSFNSTIFYSDYGTEVPTEKPAASDTVDFKEMLKQGGATPGATS
What are the official names of this protein?
Uncharacterized 31.2 kDa protein in rplA-rplJ intergenic region, ORF31.
Protein: SYI_SYNWW
Sequence: MAKGKYDGTLNLPQTGFPMRANLPQREPEILKFWDEIDIYRRIQEKNAGRPQFILHDGPPYANGNIHLGHTLNKVLKDIIVKYRSMSGYDSPYIPGWDTHGLPIEQQAIKNLGIDRHKTDVVEFREHCRDYALKYVEIQKEQFKRLGVRGDWEDPYLTLSPGFESIQIKVFGEMAKKGFIYKGLKPVYWCGDCETALAEAEVEYNEKVSPSIYVKFPVKDGKGVLPEDAFVIIWTTTPWTLPANTGICLHPGFDYVLLEVKGEKYLLAQGLLEAVAGELGWDNYQILDKYKGEELERVICHHPFFARDSLLVLGEHVTLEAGTGCVHTAPGHGEDDFHVGQEYGLEVISPVDDRGRFTAEAEKFQGLYVHDANKAVIEELEKRNMLLKAASIEHQYPYCWRCKQPIIYRATEQWFASIDGFRQDALNAIDTVKWIPSWGRDRIFNMIRDRGDWCISRQRTWGVPIPIFYCESCGEALINDETIQRVSELFAANGSDIWFAKTAAELMPPGCSCEHCGGSTFRKESDIMDVWFDSGSSHMAVLEPRQELRWPSDMYLEGSDQHRGWFNSSLSTAVAIRGAAPYREVLTHGFVVDEQGRKMSKSLGNVVDPLRMTREMGADILRLWVSSADYRNDVSVSPNIIKQSAEAYRKIRNTCRFILGNLFDFDPGKERVSYDKLSELDQWALLKLDKLIRRVTKAYEDYEFHVVFHSMHNFCTVDLSNIYFDILKDKLYCSHPQDAERKAAQTVLYDIINALVVMLTPILAFSSEEIWSYLKKEGQAESVQLLEWPQANDEYLNQAIENRMSRVLELREVVTKALEEARSKKVIGHSLGAWITIYASPEWTELLKATAGLEKIFIVSRAELKPETEAPAEALALEGVEGIRVMVQAAEGSKCERCWIIENSVGEDLKHPTLCQRCAEVVAQLQG
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_MARMM
Sequence: MARDYKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWNGKRLNIIDTPGHVDFTIEVERSLRVLDGAVCCLDANAGVEPQTETVWRQADRYKVPRMVFINKMDKLGADFFNCVKMIEDRLGATPLCVQLPIGSETEFEGVIDLIKMKELVWKGEGLGAEWEERDIRADLADKAAEYREALVETAVEQDEAAMEAYLEGEEPSEELLKSLIRKGCIALAFNPILCGTAFKNKGVQPLLDAVVDFLPNPTEVPAIKGIDFKTEEEVVRRASDDEPTSLLAFKIMNDPFVGSLTFARMYSGHLETGISLLNTVKDKKERIGRMLLMHSNSREDIKECFAGDIVAIAGLKDTTTGDTLCDPMKPVILERMEFPDPVIELAIEPKSKADQEKLGVALQRLAAEDPSFRMKTDEESGQTIIAGMGELHLDILVDRMKREFKVEANVGAPQVAYRESLSQKGLVDYTHKKQSGGSGQFARVKIEFGPGEPGSGFVFESKIVGGNVPKEYIPGVEKGLKSVMDGGLIAGFPVIDVHAMLVDGAYHDVDSSVLAFEIAARAAFREAKSHCAPKLLEPIMKVEVVTPDEYTGGVIGDLNSRRGQIAGQEMRGNATVVNAMVPLANMFGYVNNLRSATQGRAQFTMLFDHYEAVPKAVEQEVIAKSA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_SHIDS
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLELLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SHBG_RABIT
Sequence: MATPPLVPLLLLLLLLLPHAHHRLALRSVLATQRAQDSPAVHLINGLGQEPIQVLTFDLTRLVKASSSFELRTWDSEGVIFYGDTSPKDDWFMLGLRDGRPEIQMHNPWAQLTVGAGPRLDDGSWHQVHVKIRGDSVLLEVDGKEVLRLSQVSGTLHDKPQPVMKLAVGGLLFPPSSLRLPLVPALDGCLRRGSWLDPQAQISASAHASRRSCDVELQPGIFFPPGTHAEFSLQDIPQPQTEPWAFSLDLELKPSEGSGRLLALGTPEDPNWLSLHLQDQKVVLSSGMEPGLDLPLAWGLPLQLKLGVSTAVLSQGSKKQALGLPPSGLGPLLNLWAQPQGRLFLGALPGEDSSASFCLDGLWAQGQKLDMDKALNRSQDIWTHSCPSSPGNGTDTSH
What is the function of this protein?
Functions as an androgen transport protein, but may also be involved in receptor mediated processes.  Each dimer binds one molecule of steroid.  Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol.  Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration (By similarity).
What are the official names of this protein?
Sex hormone-binding globulin, SHBG, Sex steroid-binding protein, SBP, Testis-specific androgen-binding protein, ABP.
What are the subcellular locations of this protein?
Secreted. Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Protein: CCNH_MACFA
Sequence: MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLRENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVPKKSKHEEEEWTDDDLVESL
What is the function of this protein?
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex.  CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation.  CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts.  Involved in cell cycle control and in RNA transcription by RNA polymerase II.  Its expression and activity are constant throughout the cell cycle (By similarity).
What are the official names of this protein?
Cyclin-H.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUD_STAA3
Sequence: MAAIKPITTYKGKIVPLFNDNIDTDQIIPKVHLKRISKSGFGPFAFDEWRYLPDGSDNPDFNPNKPQYKGASILITGDNFGCGSSREHAAWALKDYGFHIIIAGSFSDIFYMNCTKNAMLPIVLEKSAREHLAQYVEIEVDLPNQTVSSPDKRFHFEIDETWKNKLVNGLDDIAITLQYESLIEKYEKSL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: Y603_YERE8
Sequence: MLIVISPAKTLDYQSPLATKKFTQPEMLDKSQQLIEICRELTPAQISSLMGISDKLAGLNAARFSEWQPDFTPDNARQAILAFKGDVYTGMQAQDFSAADFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIKLANPGGKDLYSFWGDQITEKLNQALEQQGDNVLINLASDEYFKAVKPAKLAGSLIKPVFLDEKNGKYKIISFYAKKARGLMSRFIIQNKLTKPEQLVDFNLEGYEFDAGLSAKNELVFKRAEQF
What are the official names of this protein?
UPF0246 protein YE0603.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: NORM_DEIRA
Sequence: MTTLPAPTISTTAELRALLRLAGPVVVSQFAANALALIATAVIGRLGERELAAAAYANAAYYLVFIMVVGVMLSVAPRVAQAHGAGDARGVARALGGGLRLALLLSAVMLPLMWALSFVLPNFAPAGVSRDLVAAYLRVYSLGMLPNLAFIALRGTLEGTGKPGAVTGVALTGVVWALLVAPALAFGWGPLPRLGLAGAAGASASAAWIMAALLWPLARRRVAYAGPLGPLGDEVRALFRLGWPIGLTLGAEGGMFSVTTLLMARFGPEVLAAHNVTMQTITAFFMVPLGIASATGVRVGTEAGAGRLAQARRAGLVGLGLSSAVMLTFAVIELAAPRTVFSVFVNVNDPANAGLIAAATGFLSIAALFQLMDGLQVTANGALRGLQDTRVPLLVSLVAYWVVGLGLGSVLSSVAGLGARGLWFGLTAGLTLAGLSLVGRFLYRTRAGRAA
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYC_ECO27
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGRYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_ANOFW
Sequence: MYVMKQSGWLEVICGSMFSGKSEELIRRVRRAQFAKQEVKVFKPAIDNRYSEEAVVSHNGTSVIAIPVSCASDIRKHITTHTDVVAIDEVQFFDEHVVDVVQQLADEGYRVIVAGLDQDFRGEPFGPVPTLMSIAESVTKLQAVCTVCGSPASRTQRLINGRPASYYDPVILIGASESYEPRCRHHHEVPDHPAKKKTSTETATRP
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK2_PYCSU
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, PycSu-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TEHB_HAEIN
Sequence: MKNELICYKQMPVWTKDNLPQMFQEKHNTKVGTWGKLTVLKGKLKFYELTENGDVIAEHIFTPESHIPFVEPQAWHRVEALSDDLECTLGFYCKKEDYFSKKYNTTAIHGDVVDAAKIISPCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNETKEKENLNISTALYDINAANIQENYDFIVSTVVFMFLNRERVPSIIKNMKEHTNVGGYNLIVAAMSTDDVPCPLPFSFTFAENELKEYYKDWEFLEYNENMGELHKTDENGNRIKMKFATMLARKK
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase.  Plays a role in both resistance to oxidative damage and heme uptake/utilization.  Also protects H. influenzae from tellurite exposure in vitro; however, since H. influenzae grows only in humans, it is unlikely to encounter tellurite in its natural environment, and it is thus probable that tellurite resistance does not represent a biologically relevant role of TehB (By similarity).
What are the official names of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase TehB, Tellurite resistance protein TehB homolog.
What is the protein family that this protein belongs to?
Belongs to the TehB family.