PharMolix/UniProtQA huggingface dataset:
Protein: CLPS_MYCLE
Sequence: MWVMVVTLAPIEPKVRPNTTWQHESAPVDITAARWVTIVWDDPVNLMAYVTYVFQKLFGYSEPHATKLMLQVHNEGKAVVSMGSRESMEVDVSKLHAAGLWATMQQDR
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: PETL_ZYGCR
Sequence: MFTIITYFGLLLAALALAVVLFVGLSKIELI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL36_VIBCH
Sequence: MKVRASVKKICRNCKVIKRNGVVRVICSEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CDHR1_DANRE
Sequence: MKNAREIQFSSFLLLAHFCFVGAQSDYAPYFYDNGPNSNNGNMALLNLSEDTPRGTQIYVLNGTDPEGQPVKYGITFEPGSKEFFRVHPKSGVVTLIEDLDREAQDEIEVFVSISDSLNKVVEKVSVFIMDANDERPQFQNMPSIVDVPENTTSGSSIYKVQAVDRDTGSGGSVTYFLQSSEQSPKFAIDHHSGVLRIKPGESLDYEKSRTHFITVVAKDGGGIYKGKQQVMSSSATLTINVIDTQDSPPIFIGTPYFGYVYEVSSPGSEIFTVSAKDGDMDNPNTIIYSLDSGADGSFSINKTSGVITLNLYPADLRREVFNIKVKALEISPEGKRLDFATTTVTIRVVDLNNHPPTFYGENGPQNVFELTMYEHPQEGEFLRGLKITVNDSDQGSNAKFNLRLVGPGRMLRVVPQTVLNEAQVTVLVEDSAAMDFEKSQFLTFKLLAVEIDTPERFSATADIIIHLLDTNDNAPKFTSDFYIARIPENSPGGSNVVSVTAMDPDSGIWGVVKYSIYGSGADIFLIQADSGIIYTQPWASLDAEVKSKYNFYVKAEDPEGKYSLAEVFVTITDLNDHPPAFNENSLEQTMVIGAPVKIEAIDEDAEEPNNLIEYSIMKADPDNIFDINADTGEIKLKPYIKSMDIVQNITNQRDCTWSVVVQAKDRGSPSFSTTTVVKIDITEATPLKGPLTSFFMNSRENPMHFLGLISGVILILVFVTVIISTVIFVRRNKANRILPSRRIIRKKRKPQKQDDFQEPFREEQEIPRADNVNFNNNIKVCSHRTPPSPPNAPVMPPPLPSHCRHGEREWTVPTVSASVASKSKKKSHRCKDNPVNTALVSELKLKLEQKNMANRY
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.
What are the official names of this protein?
Cadherin-related family member 1, Photoreceptor cadherin, prCAD, Protocadherin-21.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GREA_RHIEC
Sequence: MVEKVPMTQGGFVKLQEELRWRQQEERPRIIEAIAEARAHGDLSENAEYHAAKEAQSHNEGRITELEDLTARAEVIDLTKMSGDKIKFGAKVKLVDEDTEEEKTYQIVGDQEADVKAGRISISSPIARALIGKEVGDSIEVNAPGGSKAYEILQVSWG
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: CYB_ABROL
Sequence: MTIMRKNHPLLKIINHSFIDLPTPSNISSWWNFGSLLGICLMIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYMLSETWNIGIILFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIITAFVLVHLLFLHETGSNNPSGLNSNSDKIPFHPYYTIKDLLGVILLLMVLMILVLFFPDVLGDPDNYTPANPLNTPAH
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CINA_STREM
Sequence: MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDTFFAHRKHTARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDGVTYVVLPGPPSELKPMVKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKAKMLGIPLVELQRHGVVSSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVIGGRSRLDVRYIAALYAFNMVRKALLKSENLL
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: PURP_METST
Sequence: MGKVKKEDIMDIVEKYDKSNITIATLGSHTALHILRGAKQEGFRTAVVCEKGKEVPYERFGVADEFIFVDEYKDIVNSDVQDKLRAMNAIVVPHGSFVAYAGLSNVEDKFNVPMFGNRDILRWEAERDKERKMITQSGIRMPRKFDKPEDINKEVMVKFPGARGGQGYFICSSYEEFQNKIQEMKERNWITDSDVKDAHIEEYVCGTNFCIHYFYSALKDEVEVLGMDSRYETNIDGIVRIPAQDQIEANLSPSYVVSGNHPVVIRESLLPQVFENGDRLVETAKKLVKPGMNGPFCLQCLVNDDREIVIFEMSARIDGGTNSFMNGSAYSYIQFGEVMSMGRRISREIKNAIETDKLDVILT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ENTH_CROTZ
Sequence: MIWKRHMTLEALNATSVGTLVEHLGIEYTRLGDDLLEATMPVDTRTHQPFGLLHGGASAALAETLGSMAGYLTTRDGQCVVGTEISASHHRAVSQGQVRGVCQPLHLGRQSQCWEIVIYDEQGRRCCTSRLSTAVMG
What is the function of this protein?
Required for optimal enterobactin synthesis.  Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules.
What are the official names of this protein?
Proofreading thioesterase EntH, Enterobactin synthase component H.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_RHOPT
Sequence: MFSFDALLQAIARQTVLCVGDLMLDEFVYGEVSRISPEAPAPVIAVQRSETNIGGAGNVARNIAAIGARCIFVGLIGDDATGRFLESELGSESRIEPVLVCDGSRPTTRKVRFVSEHFSTHMLRADWETASPAAADIEQRLLDAILPQLARADIVLLSDYAKGVLTARVIRDTIDAAKKLGKRVIVDPKSANFAIYRGATLLTPNRKEFTAATRSAAATDDEIAAAAQDAMALAECEAMLVTKSEHGMTLVPRGGEPIHVPALPVKVRDVSGAGDTVAAVLAVVLASGANWAAAMRAASAAAAVAVSKNGTAVVTPAELRRRILPHASLAAEEKIIGSDAELDERLKQWRREGLRVGFTNGCFDILHPGHVKVLTAARGACDRLIVGLNSDASVRRLKGESRPVQHERARAEVLAALEAVDLVAIFEEDTPLRLITRIEPSVLVKGGDYTREQVVGHEIVAAKGGDVLLVDVLPGFSTTSLVARAREGQS
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: TRPD_YERPN
Sequence: MQHLFEKLFRAESMSQEESQQLFAAIVRGELEPSQLAAVLISMKVRGETPAEIAGAAQALLADAQHFPRPDYLFADIVGTGGDGTNSINISTASAFVAASCGVKVAKHGNRSVSSRSGSSDLLAAFGIRLDMSAEQSRLALDDLGVCFLFAPQYHTGFRHAMPVRQQLKTRTLFNVLGPLINPARPPLALIGVYSPELVLPIAQTLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNNGSIESYQLTPEDFGLNRYPLAALQGGMPEENRDILARLLQGKGETAHAAAVAANVALLLKLYGQENLRHNAQQALEMIHSGQAFDRVTALAARG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PHF6_PONAB
Sequence: MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQQLNGN
What is the function of this protein?
Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.
What are the official names of this protein?
PHD finger protein 6.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome, centromere, kinetochore. Note=Nuclear, it particularly localizes to the nucleolus.
Protein: GH_HHV7J
Sequence: MYFYINSLLLIVSINGWKHWNILNSSICVNEKTNQTIIQPGLITFNFHDYNETRVYQIPKCLFGYTFVSNLFDSVNFDESFDQYKHRITRFFNPSTEKAVKIYAQKFQTNIKPVSHTKTITVSFLPLFYEKDVYFANVSEIRKLYYNQYICTLSNGLTDYLFPITERCVMRHYNYLNTVFMLALTPSFFIISVETGMDDVVFIFGNVSRIFFKAPFRKSSFIYRQTVSDDLLLITKKTTIERFYPFLKIDFLDDIWKQNYDISFLIAKFNKLATVYIMEGFCGKPVNKDTFHLMFLFGLTHFLYSTRGDGLLPLLEILNTHQSIITMGRFLEKCFKMTKSHLLYPEMEKLQNFQLVDYSYITSDLTIPISAKLAFLSLADGRIVTVPQNKWKEIENNIETLYEKHKLFTNLTQPERANLFLLSEIGNSLVFQEKIKRKIHVLLASLCNPLEMYFWTHMLDNVMDIETMFSPCATATRKDLTQRVVNNILSYKNLDAYTNKVMNTLSVYRKKRLDMFKSISCVSNEQAAFLTLPNITYTISSKYILAGTSFSVTSTVISTTIIITVVPLNSTCTPTNYKYSVKNIKPIYNISSHDCVFCESLVVEYDDIDGIIQFVYIMDDKQLLKLIDPDTNFIDVNPRTHYLLFLRNGSVFEITALDLKSSQVSIMLVLLYLIIIIIVLFGIYHVFRLF
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: FLIT_SHISS
Sequence: MNHAPHLYFAWQQLVDKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ATPD_ACIAC
Sequence: MAELATIARPYAEALFKACAAQPGADLGSTVAWVDELAAIAADPQVRQLADNPKIESGQLFDLIAGVVRAPLSDAARNFLRVLIDNGRLEALPEVAAQFRALVNRQSGSSDAVVHSAFPIDAAALAELGASLEKRFGRKLNLSVQLDESLIGGVRVAVGDEVLDTSVKARLEQMKAALVA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: 3HID1_ARATH
Sequence: MPLLLRRFPSPSVVSSFFLRRSMASSTISSDIITPSNTKIGWIGTGVMGRSMCGHLIKAGYTVTVFNRTISKAQTLIDMGANVADSPNSVAEQSDVVFTIVGYPSDVRHVLLDPKSGALSGLRQGGVLVDMTTSEPSLAEEIAKAASFKNCFSIDAPVSGGDLGAKNGKLSIFAGGDETTVKRLDPLFSLMGKVNFMGTSGKGQFAKLANQITIASTMLGLVEGLIYAHKAGLDVKKFLEAISTGAAGSKSIDLYGDRILKRDFDPGFYVNHFVKDLGICLNECQRMGLALPGLALAQQLYLSLKAHGEGDLGTQALLLALERLNNVSVQSSDS
What are the official names of this protein?
Probable 3-hydroxyisobutyrate dehydrogenase-like 1, mitochondrial, HIBADH-like.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RLMKL_SALPK
Sequence: MNSLFASTARGLEELLKTELEKLGAVGCQVVQGGVHFQGDTRLIYQSLMWSRLASRIILPMGECKVYSDLDLYLGVQAINWTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLHLRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDETIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSEPALIALHSLLGRTMKNQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLRKNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLKTRERQKGKNQYQKMSEKGEFLEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSKGKDFLNLFSYTGSASVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKRMEESFDVQRDHVALMKDLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLIRAA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_SHIF8
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SPPA_BACSU
Sequence: MNAKRWIALVIALGIFGVSIIVSISMSFFESVKGAQTDLTSLTDESQEKTLENGSPSSKIAVLEVSGTIQDNGDSSSLLGADGYNHRTFLKNLERAKDDKTVKGIVLKVNSPGGGVYESAEIHKKLEEIKKETKKPIYVSMGSMAASGGYYISTAADKIFATPETLTGSLGVIMESVNYSKLADKLGISFETIKSGAHKDIMSPSREMTKEEKNIMQSMVDNSYEGFVDVISKGRGMPKAEVKKIADGRVYDGRQAKKLNLVDELGFYDDTITAMKKDHKDLKNASVISYEESFGLGSLFSMGANKMFKSEIDFLNMREILSQSGSPRMMYLYAK
What is the function of this protein?
Digestion of cleaved signal peptides (By similarity).  Required for efficient processing of precursors under conditions of hyper-secretion.  Has a preference for leucine-rich substrate peptides.
What are the official names of this protein?
Putative signal peptide peptidase SppA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: ENOPH_CANAL
Sequence: MTTTAKTDDIPIDTVILDIEGTVCPITFVKDTLFPYFIEKLPSILDKFQYPLSNTSASSDDQVLNILKQLPDNITKSSESIYKHFKNLVDQDIKDPILKSLQGLIWKQGYEKNELQAPIYQDSIEFIESFPTKSSTNNKIYIYSSGSIKAQILLFGHVKSTTTTITNEVIDLNPKLNGYFDITTAGFKNQSNSYKKILQEINKSSTPKSVLFLSDNINEVNAAIEAGMKSYIVIRPGNPPIDDDDDGNDDKINHKIIYSLDELDL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DCDB_METM6
Sequence: MILSDKDIFDYVNSKRVLIEPFNSKFVGPCSYDVTLGSEFIKYKDDVYDLKKNLSHNKFEIENSIMVCPLNHHLDETIIENYKEKYNVDCVVSGGLLGTTNEYVELPNDVCAQYQGRSSFGRVFLQTHQTAGWIDSGFKGKITLEIVAYDKPVILYKNQRVGQLIFSKTLSPADIGYSDRKCSKYAGQKSVMASLIKKDFEIDEEE
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: Y1629_SYNY3
Sequence: MIDQIIDEVTDSDPYQELLVTADGVAEGTLGVRLDKWLAEQLPELSRSRCQKLIESGQVQRNGLVCQDKNLILKTGDRLVVNIPELIPLDVVAQNIPLDILYEDEQLIIINKPAGLVVHPGPGHPDGTVVNALLAHCPDLAGIGGVQRPGIVHRLDKDTTGAMVVAKTELALHNLQVQLKEKTARRLYWGIVYGSPKEIQGTVNLPVGRHPGDRQKMGIVPVEKGGREAVTHWRLLERIGNHSWLEFQLETGRTHQIRVHSKQMGHPLVGDNLYTSPGSVNVNLPGQALHAHQLSLIHPVSGEIITAIAPMPAHFEKLLVYLRQRIP
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase slr1629, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: RL10_SULIK
Sequence: MKRLALALKQKKVASWKLEEVKELTELIKNSNTILIGSLEGFPADKLHEIRKKLRGKAIIKVTKNTLFKIAAKNAGINIEKLEQYLTGPNVFIFTKDNPFLTNMFFENYKLRRYAMPGDKAEEEVIIPAGDTGMPAGPILSVFGKLKVQTKVQDGKVHVVKDTVVAKPGDVIPTEALPILQKLGIMPVYVKLKIKVAYHEGLVIPAENLKLNLEGYRSNIAEAYRNAFTLAVEIAYPVPDVLKFTINKIFKNAITLASEIGYLTPESAQAVISKAVAKAYALATAISGKVDLGVKLPSAQQTQTQQSTAEEKKEEKKEEEKKGPSEEEIGSGLASLFG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SOX7_MOUSE
Sequence: MASLLGAYPWTEGLECPALEAELSDGLSPPAVPRPSGDKSSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQGKRLCKRVDPGFLLSSLSRDQNTLPEKNGIGRGEKEDRGEYSPGATLPGLHSCYREGAAAAPGSVDTYPYGLPTPPEMSPLDALEPEQTFFSSSCQEEHGHPHHLPHLPGPPYSPEFTPSPLHCSHPLGSLALGQSPGVSMMSSVSGCPPSPAYYSHATYHPLHPNLQAHLGQLSPPPEHPGFDTLDQLSQVELLGDMDRNEFDQYLNTPGHPDSAAGVGTLTGHVPLSQGTPTGPTETSLISVLADATATYYNSYSVS
What is the function of this protein?
Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors.  May be required for the survival of both hematopoietic and endothelial precursors during specification.  May play a role in skeletal myogenesis and up-regulate the expression of muscle markers, such as PAX3/PAX7 and Meox1.  Competes with GATA4 for binding and activation of the FGF3 promoter.  Represses Wnt/beta-catenin-stimulated transcription.  Probably acts by targeting CTNNB1 to proteasomal degradation.  Binds the DNA sequence 5'-AACAAT-3'.
What are the official names of this protein?
Transcription factor SOX-7, mSOX7.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LEXA_METCA
Sequence: MKPLTVRQREILDCIRRSVENEGFPPTIAEIARAIGVSSPHGVREQLRALERKGVIELIPSASRGIRLLARAEEPGLPLIGKVAAGRPLLTEAQVERYCQLGPELFEHKGDYLLRVQGMSMRDAGIIDGDLLVVQQAQEARSGQIVVVRLHDEVTVKRLRLEGALAYLEPANPEFSVIAVDPERQPLCIEGIVVGVIRTRVG
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: TRUB_SHIBS
Sequence: MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICFGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITIYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SECA_WOLPM
Sequence: MSFFFIRKIFGSTNKKIIKSFRKIVQQINALETEMQSLSDEELAGKTEEFKQELKNGKTLNDLLVPAFAVVREASRRFLNMRHFDVQLIGGMVLHNGMISEMKTGEGKTLVATLAAYLNSLEGKGVHVVTVNDYLAKRDTEWMSKLYNSLGVSVAFITNNLTDEERKEAYSADIVYSTNNELAFDYLRDNMKFSQEDMVQRGFHYGIVDEVDSILIDEARTPLIISGPVEENNQIYKHINKIVTKLVDSDYEVDEKGRTVFLTEDGISRVEELLRSYNLIPENSSLYDTDSMIMTHYIDQALRAYKLFTADKDYIVKDGKVVIIDEFTGRMMEGRRYSDGLHQALEAKENLEIQHENQTLASVTFQNYFRMYNKLSGMTGTAATEAEEFRDIYRLNVVKIPTNVPVKRVDIDDEIYGTEKEKFNAVLKFIEECYKRLQPVLVGTVSIENSEKLSALLQSHSLKHSVLNARYHEQEAYIIAQAGVPGSITIATNMAGRGTDIQLGGNAEMIAKVELKKIKNADEREKKYQEIVERVKKDKEIAIKAGGLCVVGTERHESRRIDDQLRGRSGRQGDPGLSKFFLSLEDDLMRIFGSDRMRSFLQKVGLKNNEAIHHPWINKALEKAQKKVEARNYDVRKSLLKFDDVINNQRKVIFKQRNNILGNEINDLLEVYSEVNESVVEGIIQSGYYEDYIENIVKEFHTRYGITLDKEDLAKFLNKQEALNYINDKIQEFFTEKEKYFNSQHTTDLWNTIVKQMMIMTLDHLWREHLSVLESLRQSISLRAMGQKDPLNEFKREAFLMFESMLEKWKELTIHRLAHFKLADNQEIGNRLHSARNSRLPKVSRNDKCPCNSGKKYKHCHGAVTVVS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.