PharMolix/UniProtQA huggingface dataset:
Protein: ALF_CICAR
Sequence: MSNFKSKYHDELIANAAYIGTPGKGILAADESTGTIGKRLASINVENVETNRRALRELLFTAPNVLQYLSGVILFEETLYQSTAAGKPFVDVLNEAGVLPGIKVDKGTVELAGTDGETTTQGLDGLGARCAKYYEAGARFAKWRAVLKIGPNEPSLSILSIENAYGLARYAVICQENGLVPIVELEILVDGSHDIHKCAAITERVLAATYKALSDHHVLLEGTLLKPNMVTPGSDSPKVAPEVVAEHTVRALQRTVPAAVPAVVFLSGGQSEEEATVNLNAINQVKGKKPWTLSFSFGRALQQSTLKAWSGKEENVKNAQDALLTRAKANSEATLGTYKGNSQLGEGASESLHVKDYKY
What are the official names of this protein?
Fructose-bisphosphate aldolase, cytoplasmic isozyme.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_ACOAM
Sequence: MTKRYWNINLEEMMEAGVHFGHGTRKWNPRMAPYISAKRKGIHITNLTRTARFLSEACDLLFDAASGGKHFLIVGTKKKAADSVASAAIRARCHYVNKKWLGGMSTNWSTTETRLQNFRDLRAEQKAGKIDRLPKRDAAMLKRQLSTLQTYLGGIKYMTGLPDIVIIVDQQEDYTALRECVILGIPTICLIDTNSDPDLADISIPANDDAIASIRLILNKLVFAICEGRSSYIRNR
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: M2_I96A0
Sequence: MSLLTEVETPTKNEWECKCSDSSDPLVVAASIIGILHLILWILDRLFFKCIYRRLKYGLKRGPSTEGVPESMREEYRQEQQSAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: IXTPA_DEIRA
Sequence: MQQQTGGRRRQIRRVVVATSNAGKVRELQGALAPLGWQCEGLGAVTLPEETGSTYEENAALKACAAAMATGLPALADDSGIEVLALGGQPGVYSARFGNVNSDVERNVLLLEKMRRHTDRRAKFVSVLVLAYPDGKLEEYRGEVTGQLLEGPRGESGFGYDPLFLPDGSELSMGEMTLEQKQAISHRGQALAALLAAHGA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SYNB_MOUSE
Sequence: MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT
What is the function of this protein?
This endogenous retroviral envelope protein has retained its original fusogenic properties (PubMed:15644441, PubMed:18077339, PubMed:22032925, PubMed:27589388).  Together with Syna, participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis (PubMed:22032925).  Synb is specifically involved in formation of syncytiotrophoblast layer II (SynT-II) (PubMed:22032925).  Promotes myoblast fusion, and may play a role in regeneration of damaged muscle tissue in males (PubMed:27589388).  May have immunosuppressive activity (PubMed:18077339).
What are the official names of this protein?
Syncytin-B.
What is the protein family that this protein belongs to?
Belongs to the gamma type-C retroviral envelope protein family.
What are the subcellular locations of this protein?
[Surface protein]: Cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the membrane, but localizes to the extracellular surface through its binding to TM. SUBCELLULAR LOCATION: [Transmembrane protein]: Cell membrane; Single-pass membrane protein.
Protein: RAD54_DROPE
Sequence: MRRSLAPSQRGGQRLSSRNDFTPPLLKKNKRACQQDLEQERLRQSALRDATNTSDLPLPIRFTANTEYEMAIAKVLARKFKVPIDNYVPDYGGNRTLGVRRRIVRRPLHDPLACNALVLYHAPNYTDHERMSMEPSSVLVHVVVDPLLSNILRPHQREGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVALVWTLLKQSAECKPTINKCIIVSPSSLVKNWEKEFTKWLHGRMHCLAMEGGSKENTVRALEQFSMNASTRLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYFSLVNFVNPEMLGTAADFKRNFENCILRGQNADSTDKERDRALEKTQELIKLVDQCIIRRTNQILTKYLPVKFEMVICAKLTPIQLQLYTNFLKSDQVRRSLADCKEKASLTALADITTLKKLCSHPNLICEKIAAGEKGFENSQNILPINYNPKGEINPELSGKFKLLDFMLAAIRAHGNDKVVLISNYTQTLDLFELLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDCFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEKHFTRDDLKDLFSFDPDILSDTHDKLKCKRCVQNVQMMPPPDDTDCTSHLSQWYHCSNNRGLPDNILAQAWTDSKCVSFVFHHRSQSQKIEATPATETSVEAKLEPERRKRPAMPLSDDSADEDFQGF
What is the function of this protein?
Involved in mitotic DNA repair and meiotic recombination.  Functions in the recombinational DNA repair pathway.  Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51.  In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54 (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RAD54-like, Protein okra.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDRP_RICM5
Sequence: MTKLVIHLVSDSSVQTAKYAANSAIAQFTSVKPKLYHWPMIRNLELLNEVLSKIEYKRGIVLYTIADQELRKALTKFCYELKIPCISVIGKIIKEMSVFSGIEIEKEQNYNYKFDKTYFDTLNAIDYAIRHDDGQMLNELSEADIILIGPSRTSKTPTSVFLAYNGLKAANIPYVYNCPFPDFIEKDIDQLVVGLVINPNRLIEIREARLNLLQINENKSYTDFNIVQKECLEVRKICDQRNWPVIDVSTRSIEETAALIMRIYYNKKNKYNK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RIX1_PICGU
Sequence: MLPLAVILSELQEPKTIVPVLSSLRSGSPVWSNISGPDQKHLVSRTLNLTRSSIQFRRWFGINVIRVLADNYKIMAGDGSQIIGQLLKLLEQCNQFTSAVYFKSLVECIDHVCDSIRGKPTMTRELLTPNLPAIIGLYLEKFSHDPAYLVSRLAPYIRAHPTTFRPFGNKLRSKIMETILSPAFSNFPDSSKDIFCNTLSTLCAVEKIEPEERWSSDLFSLIGELSNTLEIYGEFLNFEDDAELGKLLKKIPRSSSGESEFPSLSIDINDPSSFYSLPERLDILLRLIRGYLSAPTSFVAKVPLGIIALVVEAVLSINSRFIPFKREIRDESTKQIIRNTLQCAHSSALGLLKVLPSIFRGSLVPYMRRILGLLETLIPMKKKSLDTDQIVANEQFICLVLDCVACNISLVSYYQDSTGLVRLIDAAMAIVQPRSSSNTSSNTANTISSNGKKKKKQASVPLADVLSHQHLFNISVSESTTNHVQSFVNTLISCADLPSAQHNKVCKFVIVEAVKASHHIQEGTVPKQLRNLLVNAVLHPGFETTSILPIVCSILKEDELLSVFRNPRFPPVLKAVEVKEEEEEEEEEEESEEEPEEAEEAEEVVNGSRTEREVAPETKEVEPENKRRKIEIPEAVSVEPQVSEPQISTSLQHSISNQPEPAEPKNLRAPEPVKQANNPKLTEPSAAKDLREDFSDDSDFEMPEIDVDSDDE
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits.  Regulates pre-60S association of the critical remodeling factor MDN1.
What are the official names of this protein?
Pre-rRNA-processing protein RIX1.
What is the protein family that this protein belongs to?
Belongs to the RIX1/PELP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBE2N_HUMAN
Sequence: MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
What is the function of this protein?
The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains.  This type of polyubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  Plays a role in the control of progress through the cell cycle and differentiation.  Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.  Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair.  Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD.  Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes.  Together with RNF135 and UB2V1, catalyzes the viral RNA-dependent 'Lys-63'-linked polyubiquitination of RIGI to activate the downstream signaling pathway that leads to interferon beta production (PubMed:28469175, PubMed:31006531).  UBE2V1-UBE2N together with TRAF3IP2 E3 ubiquitin ligase mediate 'Lys-63'-linked polyubiquitination of TRAF6, a component of IL17A-mediated signaling pathway.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 N, Bendless-like ubiquitin-conjugating enzyme, E2 ubiquitin-conjugating enzyme N, Ubc13, UbcH13, Ubiquitin carrier protein N, Ubiquitin-protein ligase N.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LC7L2_HUMAN
Sequence: MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI
What is the function of this protein?
May bind to RNA via its Arg/Ser-rich domain.
What are the official names of this protein?
Putative RNA-binding protein Luc7-like 2.
What is the protein family that this protein belongs to?
Belongs to the Luc7 family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Note=Colocalizes with SCNM1 and SNRNP70 in nuclear speckles.
Protein: EXD1_HUMAN
Sequence: MEDSEFLAYVELLDEVEQGSVRAKASSVSLHAERTWMEKMKVEDLNVCEPASPAPEAPATSLLNDLKYSPSEEEEVTYTVINQFQQKFGAAILHIKKQNVLSVAAEGANVCRHGKLCWLQVATNCRVYLFDIFLLGSRAFHNGLQMILEDKRILKVIHDCRWLSDCLSHQYGILLNNVFDTQVADVLQFSMETGGYLPNCITTLQESLIKHLQVAPKYLSFLEKRQKLIQENPEVWFIRPVSPSLLKILALEATYLLPLRLALLDEMMSDLTTLVDGYLNTYREGSADRLGGTEPTCMELPEELLQLKDFQKQRREKAAREYRVNAQGLLIRTVLQPKKLVTETAGKEEKVKGFLFGKNFRIDKAPSFTSQDFHGDVNLLKEESLNKQATNPQHLPPTEEGETSEDSSNKLICTKSKGSEDQRITQKEHFMTPKHEFQASLSLKEETEQLLMVENKEDLKCTKQAVSMSSFPQETRVSPSDTFYPIRKTVVSTLPPCPALEKIDSWISPFLNLP
What is the function of this protein?
RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis.  The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity (By similarity).  The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.  In the PET complex, EXD1 probably acts as an RNA adapter.  EXD1 is an inactive exonuclease (By similarity).
What are the official names of this protein?
piRNA biogenesis protein EXD1, Exonuclease 3'-5' domain-containing protein 1, Exonuclease 3'-5' domain-like-containing protein 1, Inactive exonuclease EXD1.
What is the protein family that this protein belongs to?
Belongs to the EXD1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: SERC_SHEB9
Sequence: MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLRELMQIPANYHVLFMHGGGRGQFSAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFNTPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMNVTFQLVNEALDGEFLKQAQIAGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAAKHS
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_MACCJ
Sequence: MGKYFGTDGVRGVANSELTPELAFKLGRFGGYVLAHNGTEKPTVVVGRDTRISGVMLESALVAGLLSTGAEVMRLGVITTPGVAYLTREMNAQAGVMISASHNPVQDNGIKFFGADGFKLSDAQEAEIEALLDAEEDTLPRPVGVELGHTSDYFEGGHRYLSYLKSTIEGDLEGLKIALDGAHGSTYSLAPYLFGDLEADTVTIGCNPDGNNINDGVGSTHPEKLAELVLDTDSDFGLAFDGDGDRLIAVDEQGQIVDGDQIMFILAQDMDARGELKDHMVVSTVMSNLGFYKGLESLNIKSDKTKVGDRYVVEEMRRSSYNLGGEQSGHIVMMDHNTTGDGLLTGIHLASIVKRSGKTLSELAGQMTKYPQRLVNIKVSDKHAVEQNEHVAAVIKEVEDEMNGEGRVLVRPSGTEPLVRVMVEAKTDEDAERFVNKISDVVRAHMGL
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SECA_FLAPJ
Sequence: MSFINNILKVFVGDKSQKDVKAIQPIIAKIRTLENSLSNLSHDELRAKTVYFKDIIKQARAEKDTKIENLKLEVEAIQDIDAREDVYAQIDILEKEAYEISEKTLNEILPEAFAVIKETAKRFKENKQITVTATAKDRELSATKSYINLVGDTAVWANSWSAAGKEITWDMIHYDVQLIGGVVLHQGKISEMQTGEGKTLVATLPLYLNALTGNGVHLVTVNDYLAKRDSAWKAPLFEFHGLMVDCIDLHQPNSDARRKAYDADITYGTNNEFGFDYLRDNMAHSPEDLVQRKHNFAIVDEVDSVLIDDARTPLIISGQVVDGDRHEFTELKPKIENLVNIQRQLANGFLTEAKRLIKEGNTKDGGFQLLRAHRALPKNKALIKFLSEEGIKALLQKTENQYMSDNNREMPKVDEALYFVIEEKNNQVELTDSGIEIMSKDTEDTFFVLPDIGTEIARIEKLNLSTEEQGEQKEKLFQDFSVKSERIHTLTQLLKAYTLFEKDTEYVLMDNKVMIVDEQTGRIMDGRRYSDGLHQAIEAKENVKIEDATQTYATVTLQNYFRMYSKLAGMTGTAVTEAGELWEIYKLDVVEIPTNRGMSRIDKEDLIYRSVREKFNAVIEDVVGLSQSGRPVLIGTTSVEISELLSRMLKMRNIPHNVLNAKMHKQEAQIVEEAGKPGVVTIATNMAGRGTDIKLTAEVKAAGGLAIIGTERHDSRRVDRQLRGRAGRQGDPGSSQFYVSLEDNLMRLFGSDRVAKIMDRMGLQEGEVIQHSMMTKSIERAQKKVEENNFGTRKRLLEYDDVMNSQREVVYKRRRHALHGERLKLDIANMMYDTCEVIVEKNKLTGDFKNFEFELIKNLSITSPVTQADFAKLSDIELTGKTYKAASEYYTEKNIRDAHEAFPIIRNVYENPGNSFERIIVPFTDGIKSLNVVTDLKKAYESQGKQLVADFEKNITLAIVDDAWKKHLRKMDEMKQSVQLAVHEQKDPLLIYKFEAFKLFKNMLDGINKEVISFLFKGDLPQQQNNIQEATQIRQKENYIESKDEILNIEEQAERNHEAGQTQQHQVTETIVRDMPKINRNDTVKIQNVANGQIEELKFKKAEILLNAGTWVLVSE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: TRPR_CHLTB
Sequence: MKNQEESGWQAFLTLCSKMQKEKFLQDLFSLFLSFGERKDVASRYHIIRALLEGELTQREIAEKYGVSIAQITRGSNALKGSDPQFKEFLQKEI
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
What are the official names of this protein?
Trp operon repressor homolog.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_COXB2
Sequence: MLKIVSKPSFNRIALMGREGVEGVPETLAALKDYLVSLNREVILEENAAHMIDGSRLLTVPANDLKKKADLLIVVGGDGSLLNAAHIAVPQQLPVLGINRGRLGFLTDIPPNELTQISDILDGHYREEVRFLLEGTVEEGDEIVAQGIALNDIVLLPGNAPKMIEFDIFINDEFVCNQRADGLIITTPTGSTAYALSGGGPILHPQLNAMALVPMFPHTLSSRPIVVDAESQIKITISPENDVSPYVSNDGQERVSIKPGGNVYTRKYHYPLHLIHPTDYNYYDTLRRKLDWEKRAAKV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PD3_SCHPO
Sequence: MVTFMVFGASGNLANKKTFPALFHLFKRNLVDRSSFYVLGYARSKIPIGEFRESIRESVKPDTESKQVFQDFIDRVSYFSGQYDQSSSYVEFRKHLESVEKKADSSKALRIFYIALPPSVYVTVSSHIYENLYLPGKSRLVIEKPFGKNYQSAVKLKEEVHKHWKEEEIYRIDHYTAKDMVNNFFTLRFANSSSIDAVLNRHSIQSVEIHMYETGGCEGRIGYYDANGVVRDVVQNHLTQIFCIAAMNEPKSASASDVRAEKVNLLKATRPASLKESMLGQYTTSEDGKIPGYLDLEGVPKDSKATTFAASTLHVDNDRWKGVPFVFVSGKRMKKGEVYIKYYFRLKDSGIFSDVKRRRYLILHVQPEEFVNLTCTINKPMTTDLQPIDAYASLNYNEQFKDLMKEKRDGYEILFEDAIRGDPTKFIRYDEVEYAWKIWDEILDSPKKPIPYPAGSDGPEGLEAYMKRHLGHE
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity).
What are the official names of this protein?
Probable glucose-6-phosphate 1-dehydrogenase C7.13c, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOMEZ_HUMAN
Sequence: MVRGWEPPPGLDCAISEGHKSEGTMPPNKEASGLSSSPAGLICLPPISEELQLVWTQAAQTSELDSNEHLLKTFSYFPYPSLADIALLCLRYGLQMEKVKTWFMAQRLRCGISWSSEEIEETRARVVYRRDQLHFKSLLSFTHHAGRPPEEVPPPPVPAPEQVGIGIGPPTLSKPTQTKGLKVEPEEPSQMPPLPQSHQKLKESLMTPGSGAFPYQSDFWQHLQSSGLSKEQAGRGPNQSHGIGTASWNHSTTVPQPQARDKPPPIALIASSCKEESASSVTPSSSSTSSSFQVLANGATAASKPLQPLGCVPQSVSPSEQALPPHLEPAWPQGLRHNSVPGRVGPTEYLSPDMQRQRKTKRKTKEQLAILKSFFLQCQWARREDYQKLEQITGLPRPEIIQWFGDTRYALKHGQLKWFRDNAVPGAPSFQDPAIPTPPPSTRSLNERAETPPLPIPPPPPDIQPLERYWAAHQQLRETDIPQLSQASRLSTQQVLDWFDSRLPQPAEVVVCLDEEEEEEEEELPEDDEEEEEEEEEDDDDDDDDVIIQD
What is the function of this protein?
May function as a transcriptional regulator.
What are the official names of this protein?
Homeobox and leucine zipper protein Homez, Homeodomain leucine zipper-containing factor.
What are the subcellular locations of this protein?
Nucleus.
Protein: RODZ_ECO7I
Sequence: MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELNNNQSQSVPLDTSTTTDQAMATTPTSPVDTTATNTQTPAATTAPSPTVDSQQNAVVPPSQANVDTAATPAPAATTTPDGAAPLPTDQAGVTTPAVDPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSPAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: CYAA_NEUCR
Sequence: MTRNDGGSRYSSIDSAQSSITAKPFPLTPTSSLGSSMTRPLSPSLQAGSSSSNGGHNVSRSASQGARRPAPTRLKTDDGTQFASRSSRDFESSQSQSQPSHTQTRSHSLSQATLQSCSQPQLSLNSQQSQSPSQYHSQQTPTQQQPQQQVSPTGGSRLTQSPTTPSNASIREHRMSELGGYRREMAAMLDTTGGALSRTSSHSQQQPQQPQQQQQQQQQQQGHAAGSVSGTFSNLSQYAPYLGGNNGGGMSMGSFLNDSTDNLSVISQLSPGIRPMTARPSQASAGSMEFPDSAYYDDERRPSIASITTTASSQGSRTSKTRGGLQKLQQFFGDRDDWPGRDSSEISLPQPSHSGPMSTGKEHRSHSYSLPGSGRSHRDRNYSNATDHHPSTFGSVSTVGGRDRDASPVPSRPRTPVPAPEVVPFLYQEADDIARYGEAPVRTSLTGPDRDRYIDSSQNPPKTSSSARSGHSIVHLPGHHKHNKSNEDPRALKPSLSREDSAASFARDFRNGSSSMMGTRSRAQSPAPSWTGTSRGLKANSISDGTSSPAPSHKKGILGRFRRHNKDKEDGSSLRSGSNHTLVHRPSRQDLTRAAESTYPASVYVSDPSEQREVPVRPGYVRQTTAPGFTTKLFTSKKSSSAKQPQDDMDEDIGPTDMHMGGGTVYHLDTNLNDMEGILTKPQPMTPLDNSISMRRESEKMIVPITTDPEGAWAAPDSWAVRDNKKSLAPQVNEDLCSRQPSEEKEKKSNYYIRVFRSDSTWTTLTLPLTATAEDVIMGVAKKTYLPPGAQDSYSLLIKKHDLFRVLNSAEQPLRIQKRLFQQIGYQEKDGIDEIGREDNSYICRWVFLKEKEADMHLLSPDINFRNQKLNHVDLSGRNLITIPVPLYRKAAEIVSLNLSRNLSLDVPRDFIQACTALRDIKYNNNEAQALPKSFATASKLTYLDVSNNRLQDLDHSELSKLTGLLKLNLANNCLRSLPPTLGAYKSLRTLNISSNFLDVFPSFICELETIVDLDLSFNSINNLPDNLMKLRNLEKFVITNNRLSGPISESVRDLVSLRELDIRYNQISTIDVLSDLPRLEILSADHNQISKFSGSFERLRSLKLNSNPIVKFEVKAPVPTLKILNLSNAQLASIDESIDNLMNLERLILDSNYFVSLPNQIGNLKKLDHLSMANNHLGELPPEIGCLTELRTLDVHGNNMRKLPNEIWWANKLEHLNASSNILTEFPKPASRAPQAPGEASPSPGAYPFPNANKNGLLSRTPSMDDLNGDASRRPSQASSTLLGVAVSPVPSGPDNRKSSMVSLYGKGGRKTSVVSRSTTQSSTGVITPSNGPRKDSSLSYRFTHTFSGSLKNLYLADNQLDDDVFEELKHLPELRVLNLSCNDLSDMPQGTIRSWPQLVELYLSGNELTSLPAEDFLEEHCLLQTLHINGNKFINLPAEISRAKKLQVLDCSSNNLKYNVTNVPYDWNWNFNRDLRYLNLSGNKRLEIKNNYRQPQSYRDDDFADTDFSKLTNLRVLGLMEVTHTLPNIPDQTEDRRVRTSEMKAGAYLPYGMADTLGKNEHLSLFDLVVPRLGSVETDTLVALFDGKELSTGGSKIAKFLYEEFSRLFILELEKVKGKPNENPADALRRTFLSVNKLLMSLSNSADERGLDSHPSRNYAHTVLTKEDLNSGCVATVAYLSELKLYVANVGDVQGMLIQANGSFKMLTKKHDPADPVERSRIRNAGGWVSRNGRLNDVLNVSRAFGYTELLPAVQAAPDITEHTIDDKDETVLIASKELWEHLRPELIVDVARECRSDLMKASQKLRDLAIAYGSTNKLLIMMIGVANLKQRQAQQFKGQLNATFSMPQDDPSHVPPSGNKRRKVRAEGPLDSNLMRLNAEVPPPTGQLSIVFTDIKNSTQLWENYPEAMRLAIKLHNEVMRRQLRMIGGFEVKTEGDAFMVSFPTATSALLWCFAVQMKLLTVDWPPEVLSNSSCQPIYDRNNNLITRGLSVRMGAHWGEPLAERDPVTRRMDYYGPMVNKASRISAVADGGQITASSDFITEIHRCLETYKESVDVDEDSLEDDATAKAIRAELRALSSQGFEVKDMGEKKLKGLENPELVYSVYPHALVGRTEQHHAHTESTQNQAALQPYGALATPKPATMDPDSEIQFEPETIWALWRVALRLEMLCSTLEEPNARGLQAPETELLERMKQRAGEVTDHFLLNFMEHQISRIETCITSLAVRHIAIGSGPITKLNDLRAPMNDVLSTLKEQMDELARYKAKYGSLDQAETDDATDNNSSGDVDTLDGSDTEQE
What is the function of this protein?
Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase, Crisp-1.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.