PharMolix/UniProtQA huggingface dataset:
Protein: CNGC1_ARATH
Sequence: MNFRQEKFVRFQDWKSDKTSSDVEYSGKNEIQTGIFQRTISSISDKFYRSFESSSARIKLFKRSYKSYSFKEAVSKGIGSTHKILDPQGPFLQRWNKIFVLACIIAVSLDPLFFYVPIIDDAKKCLGIDKKMEITASVLRSFTDVFYVLHIIFQFRTGFIAPSSRVFGRGVLVEDKREIAKRYLSSHFIIDILAVLPLPQMVILIIIPHMRGSSSLNTKNMLKFIVFFQYIPRFIRIYPLYKEVTRTSGILTETAWAGAAFNLFLYMLASHVFGAFWYLFSIERETVCWKQACERNNPPCISKLLYCDPETAGGNAFLNESCPIQTPNTTLFDFGIFLDALQSGVVESQDFPQKFFYCFWWGLQNLSSLGQNLKTSTYIWEICFAVFISIAGLVLFSFLIGNMQTYLQSTTTRLEEMRVKRRDAEQWMSHRLLPENLRKRIRRYEQYKWQETRGVDEENLLSNLPKDLRRDIKRHLCLALLMRVPMFEKMDEQLLDALCDRLQPVLYTEESYIVREGDPVDEMLFIMRGKLLTITTNGGRTGFLNSEYLGAGDFCGEELLTWALDPHSSSNLPISTRTVRALMEVEAFALKADDLKFVASQFRRLHSKQLRHTFRYYSQQWKTWAACFIQAAWRRYIKKKLEESLKEEENRLQDALAKEACGSSPSLGATIYASRFAANILRTIRRSGSVRKPRMPERMPPMLLQKPAEPDFNSDD
What is the function of this protein?
Acts as cyclic nucleotide-gated ion channel.  Can be activated by cyclic AMP which leads to an opening of the cation channel.  May be responsible for cAMP-induced calcium entry in cells and thus should be involved in the calcium signal transduction.  Could transport K(+), Na(+) and Pb(2+).
What are the official names of this protein?
Cyclic nucleotide-gated ion channel 1, AtCNGC1, Cyclic nucleotide- and calmodulin-regulated ion channel 1.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREG2_BRUC2
Sequence: MKKIPRIGVGGPVGSGKTAIIEAVVPILIKLGYRILVITNDIVTTEDAKHVQRTLKGVLIEDRIVGVETGGCPHTAVREDPSMNLAAVEEMEAKFPDTDLVLLESGGDNLTLTFSPALIDFFIYVIDVAAGDKIPRKNGPGISQSDILVINKTDLAPYVGASLQVMDDDSRMMRGKKPFVFTNCKTNEGIDDLVHLIRENVLFDTEVSKESA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 2.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_VIBVU
Sequence: MRIEQELKLGFKDVLFRPKRSTLKSRSQVNLTREFTFKHSGRQWSGVPVIAANMDSVGSFEMAKALSQHGVMTAIHKHYTVQDWADFVKDADSETLNKVMVSTGTSEADFQKTKDVMALSDELIFICIDIANGYSEHLVQYVQQVRAAFPDKVISAGNVVTGDMVEELILAGADIVKVGIGPGSVCTTRVKTGVGYPQLSAIIECADAAHGLGGRIIGDGGCACAGDVAKAFGGGADFVMLGGMLAGHEESGGEIVLKDGESYMKFYGMSSKSAMDKHSGGVAGYRAAEGKTVLLPYRGSVHGTIQDILGGVRSTCTYVGAAELRELTKRTTFIRVLEQENNVFGKEK
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: GLHA_BOSMU
Sequence: MDYYRKYAAVILAILSLFLQILHSFPDGEFTMQGCPECKLKENKYFSKPDAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNVRVENHTECHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: GMHA_PSEAB
Sequence: MDMQHRIRQLFQASIETKQQALEVLPPYIEQASLVMVNALLNEGKILSCGNGGSAGDAQHFSSELLNRFERERPSLPAVALTTDSSTITSIANDYSYNEVFSKQIRALGQPGDVLLAISTSGNSANVIQAIQAAHDREMLVVALTGRDGGGMASLLLPEDVEIRVPSKITARIQEVHLLAIHCLCDLIDRQLFGSEE
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKNS_MYCGE
Sequence: MEAILKIGDIVENKYQIEKLLNRGGMDSYLFLAKNLNLKNYGPVQKKQYGHLVLKVVQKNPKINENNWKKFLDEMVTTTRVHHSNLVKSFDVVNPFLKIVRGNKTIALNQIVMIAMEYVDGPSLRQLLNRKGYFSVSEVVYYFTKIVKAIDYLHSFKHQIIHRDLKPENILFTSDLTDIKLLDFGIASTVVKVAEKTEVLTDENSLFGTVSYMIPDVLESTVNKAGKKVRKPPNAQYDIYSLGIILFEMLVGRVPFNKSINPNKERETIQKARNFDLPLMQATRSDIPNSLENIAFRCTAVKRENNKWLYSSTKELLEDLANWENEQAMIKPANERVLEGQVEIREMMLEKPLAWYFKTWALSIFTIVFIGLIIAAIVLLLIFNARF
What are the official names of this protein?
Putative serine/threonine-protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYF1_KLULA
Sequence: MEIDKFVKEEDIPFEYGVVRERDNAVSWSRYLATKRSAGDELNLDWLYERCLKEIKDDWHLWKEFLKWRIELLNDCDIFRHKDEYNKISLLFEQCLTSCGKVGDAWIMYMEWVIQFKDLKRIRELLGKALRSMSWEYHEAIWRVVIDFIINELLIDNKRYELSLEDSIYYFVHGEHSTNFDTDLWSSSILQRYSLICDDIEPLLIYIFKTHDWSTIVRVFEKHLSPNLKPSQTSLFELYVSYITSMILVDNSAGVAAVVDQCIELFPFKKGELKTYLIFNLIRQGKITEAELYLEKVISETKDIIEFSVLYDFWIRMEELLTQELIQKMKDDNSEKQRLFANIRLHADTLTSLIKNHTIRLNDLELRREPNNIKLWLERVKLFDTISDKAKVYADAVLTVDYRLQTTPGLLGELWCQYCRLFEEDIEKSEVLLDKATNVPFKFLVDLENVWLYWCEYRLKRSIDDAIKVLSVVLEIPDNHELLLQKFEKGESPAQAAIFSSKRLWAMYLDLLEVKGNYGTAVNAYETAILIKAATPAMFINYALLNESSGHQAEALAVFERSVEIFPPSVSKSIWDIYLDVALKADITKEQKRDIFESAIKLAASGVACVSFFEKYSDFELNLGFHERSVEILHKGAKNISDLESKCTLWEECINRSEKQLDVNHTRKLYEECIETLPNSKAIKFLLPFAILEESRNEVARCRALLDYGSKLLKPAQNEELWDFWRNFETMHGTKDSFKNMLKARRFLEDTMKVNTEEVSRHADSIEFRASTAKISGSGPPSAEDKGYSNTAEIDLGL
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle progression.
What are the official names of this protein?
Pre-mRNA-splicing factor SYF1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL6_TROW8
Sequence: MSRVGKLPIEIPVGVEVCVNGRTVSITGPKGSLYLDIAEQIGVSVSDGKVLVSRSDDSRTARALHGLTRALIANNVHGVLHGYTKTLEIVGTGYRVSKKGENLELALGFSHPVFVDPVPGVSFGVEGNSKIIVSGIDKQAVGEAAASIRKLSKPEPYKGKGIRYSDEIVRRKVGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RR19_ARATH
Sequence: MTRSLKKNPFVAKHLLRKIEKLNTKAEKEIIITWSRASTIIPTMIGHTIAIHNGREHLPVYIIDLMVGHKLGEFSPTINFRGHAKNDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y663_MYCPA
Sequence: MARTDRDRWDLATSVGATATMVAAQRALSSDANLIDDPYAAPLVRAVGIDVYVRLVDGEIQPGTSEFDPHRMAKGMACRTRFYDDFFLDAARAGVGQAVILASGLDARAYRLPWPAGTVVYEVDMPDVIEFKTLTLADLGAQPTAQRRTVAIDLRDDWAAALREERFDTQAPAAWSAEGLLVYLPEQAQDALFDNITALSAPGSRLAFDFVPDTAVFADPRWRAHHDRMSELGFEVDFNDLVYHGERSHIVDHLSGRGCSLVPLFRVG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_0663.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: B2CL1_RAT
Sequence: MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
What is the function of this protein?
Isoform Bcl-X(S) promotes apoptosis.
What are the official names of this protein?
Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
[Isoform Bcl-X(L)]: Mitochondrion inner membrane. Mitochondrion outer membrane. Mitochondrion matrix. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. Note=Localizes to the centrosome when phosphorylated at Ser-49 (By similarity). After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner.
Protein: PPDE_DEIRA
Sequence: MRVLFIGDVFGQPGRRVLQNHLPTIRPQFDFVIVNMENSAGGFGMHRDAARGALEAGAGCLTLGNHAWHHKDIYPMLSEDTYPIVRPLNYADPGTPGVGWRTFDVNGEKLTVVNLLGRVFMEAVDNPFRTMDALLERDDLGTVFVDFHAEATSEKEAMGWHLAGRVAAVIGTHTHVPTADTRILKGGTAYQTDAGFTGPHDSIIGSAIEGPLQRFLTERPHRYGVAEGRAELNGVALHFEGGKATAAERYRFIED
What is the function of this protein?
Has a dual activity phosphatase/phosphodiesterase in vitro, with a preference to phosphoenolpyruvate (PEP) and 2',3'-cAMP, respectively.  Can also use 2',3'-cGMP, 2',3'-cCMP and various model substrates such as p-nitrophenyl phosphate (pNPP), bis-p-nitrophenyl phosphate (bis-pNPP) and p-nitrophenyl thymidine monophosphate (pNP-TMP).
What are the official names of this protein?
Phosphatase/phosphodiesterase DR_1281, 2',3'-cyclic-nucleotide 2'-phosphodiesterase, Calcineurin-like phosphoesterase, Phosphoenolpyruvate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the YmdB-like family.
Protein: G11A_ORYSJ
Sequence: MASKAMPRAPPAAPNLQSLKLCSQNDSSLETTSPSKRSALVPGRSAESSKPNPEVVQKEQKSTQHQNESIDLTGSNDPAEVKAEGNLVPKRLADEEKGVVEDGIANGSLKSSSALGKEHGIASASGSARLVGRSETGERGFSSSRCRPSTSSDVSDESACSSISSVTKPHKANDSRWEAIQMIRTRDGILGLSHFKLLKKLGCGDIGSVYLSELSGTKSYFAMKVMDKASLASRKKLLRAQTEKEILQCLDHPFLPTLYTHFETDKFSCLVMEFCPGGDLHTLRQRQRGKYFPEQAVKFYVAEILLAMEYLHMLGIIYRDLKPENVLVREDGHIMLSDFDLSLRCAVSPTLIRSSNPDAEALRKNNQAYCVQPACVEPSCMIQPSCATPTTCFGPRFFSKSKKDRKPKPEVVNQVSPWPELIAEPSDARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVIGQPLRFPEYPVVSFSARDLIRGLLVKEPQQRLGCKRGATEIKQHPFFEGVNWALIRCASPPEVPRPVEIERPPKQPVSTSEPAAAPSDAAQKSSDSYLEFDFF
What is the function of this protein?
May play a role in the regulation of metabolism and signal transduction processes.
What are the official names of this protein?
Protein kinase G11A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: KCC2A_HUMAN
Sequence: MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in various processes, such as synaptic plasticity, neurotransmitter release and long-term potentiation (PubMed:14722083).  Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity).  Regulates dendritic spine development (PubMed:28130356).  Also regulates the migration of developing neurons (PubMed:29100089).  Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378).  Phosphorylates the transcription factor ETS1 in response to calcium signaling, thereby decreasing ETS1 affinity for DNA (By similarity).  In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (PubMed:11972023).  In response to interferon-beta (IFN-beta) stimulation, stimulates the JAK-STAT signaling pathway (PubMed:35568036).  Acts as a negative regulator of 2-arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Synapse. Postsynaptic density. Cell projection, dendritic spine. Cell projection, dendrite. Note=Postsynaptic lipid rafts.
Protein: DEE76_AUXPR
Sequence: MWRSWLREAHQSFERLPYESKQDRVVEDISKAIMSIKEAIFGEDEQSSSKEHAQGIASEACRVGLVSDLVTYLTVLDFETRKDVVQIFCAIIRITLEDGGRPGRDYVLAHPDVLSTLFYGYEDPEIALNCGQMFRECIRHEDIAKFVLECNLFEELFEKLNVQSFEVASDAFATFKDLLTRHKQLVAAFLQENYEDFFSQLDKLLTSDNYVTRRQSLKLLGELLLDRVNVKIMMQYVSDVNNLILMMNLLKDSSRSIQFEAFHVFKVFVANPNKTKPVADILVNNKNKLLTYLEDFHNDRDDEQFKEEKAVIIKEISMMHA
What are the official names of this protein?
Degreening-related gene dee76 protein.
What is the protein family that this protein belongs to?
Belongs to the Mo25 family.
Protein: DGTL1_RHOP2
Sequence: MSVGMAAPRAAFSCDPDRSRGRQFAEPPSSNRSAFRRDCDRVIHSNAFRRLKHKTQVFVFHEGDHYRTRLTHSLEVAQIARAIARQLGLDEDLTETLALAHDLGHPPFGHAGERALDACLRDHGGFDHNAQTLRVLTALEHRYPGFDGLNLTWETLEGVVKHNGPLTDRTGAPLPRHAERGVPIGIAEFSQRFDLEIWSFASLEAQVAALADDIAYDAHDIDDGLRAGLFRVDDLRAVPLTAALIDGISRRYPALGESRRGAELVRELISHLIGAVTAETMRRLGEAAPRSVEDVRHASTAMVAFPSETAVAEAEIKAFLWTHMYRAERVMAVMRDAEAIVADLFRRYCEHPADLPPDWLPADGPVAECEADRFRRIRNFIAGMTDRYALTEHQRLFDSTPDLR
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: URK_LIMRD
Sequence: MSIQQNKRPVVIGVTGGSGSGKTTVSNKIYDQLHGQAIQIINQDTYYNDQSDMTMDERKAVNYDHPLAFDTDFLIKQLTDLRSNKAIEMPVYDYTQYTRSDKTVHVEPTDVIILEGILILDDERLRDLMDIKVYVDTDDDIRIIRRIQRDMVERGRSLDSIITQYLATVKPMYHQFVEPTKRYADIIVPEGGENQVAIDLLSTKIRDILVKRGHTELR
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_CALBD
Sequence: MAKGSLNLQDLFLNQLRKEKVNVTIFLLSGFQLKGVIKGFDNFTLIVETDNNKQQLIYKHAISSIMPSKPINYMAQAQNNQQASQQSNNNQG
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: KMO2_ASPNC
Sequence: MTADGKIVIVGGGPVGSLAALYASHYHDNVEVYELRDERQNPAGASPLLQKSINFTLSERGIRALEKSGRTDLLRAIMRTAIPMHGRMVHGRMVHGRSVSGKLQETFHQYDVHGNSLYSLDRKALNIALRQELDATPNVKMFFHHKLIRADMNTRKVWFEQREDPSTSTSPSTSSTPKEVPFDFLIGADGAHSTTRQQIMRYTPLDYQQQYADTVWCELRIPPTEKTNSFRLPPNYLHIWPGGEYMFCAFPCPDQSFNCILFAPASRLDALKSSPPATLFDFFDTHFPGVCPDLISQSSLSQQFYQSPHLPLIGIKCSPHHLGSAAVIIGDAAHAMFPFYGQGLNAGMEDVRILFDLLDEHRVFGHGKSLDKDHARAAALTEYSNQRVRDAHAIHDLSRRNYLELRGGVNSPVYKARKFVEEALQRYVPLLGWRTLYSRVSFSDQRYSEVVVKNELQGWVLLLMSGLGVLLHVLVFGALGGAFLGLKR
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase 2, Biosynthesis of nicotinic acid protein 4-2, Kynurenine 3-hydroxylase 2.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: DXS_PHOV8
Sequence: MEQDNLYNLLQSIDTPDDLRHLSADKLPEVCKELRQKIIDELSCNPGHFGSSLGVIELTVALHYVFNTPYDRIVWDVGHQAYGHKILTGRRDAFCTNRKLNGIRPFPSPSESEYDTFTCGHASNSISAALGMAVAAKKHGENNRHVVAVIGDGSMSGGLAFEGLNNASATPNNLLIILNDNNMAIDRSVGGMKQYLLNLQMSEGYNRIRYKISQMFHRWGILNEERRKSLIRFNNSLKSMLVQQQNVFEGMNIRYFGPIDGHDVNNLARVLKEIKDMQGPKLLHIHTTKGKGFGPAEKAATIWHAPGIFDKETGERIVVDTKGMPPLFQDVFGNTLLELAQTNDKIVGVTPAMPSGCSMNILMKAMPERGFDVGIAEGHAVTFSGGMAKDGLLPFCNIYSSFMQRAYDNVIHDIAIQKLNVVLCLDRAGLVGEDGPTHHGAFDLAYMRPIPNLIVASPYNEHELRCLMYTAQLPDKGPFVIRYPRGRGSLVDWKCPMQEIEIGKGRKLKEGKDIAVITLGPIGVQAEKAITHAEQETGKSIAHYDLRFLKPLDESMLHEIGKRFKQVVTVEDGVLKGGMGSAILEFMADNEYNPQIKRIGLPDQFVQHGSVKELYHICGMDEEGIYKVLISF
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MURC_PSEA6
Sequence: MIAPDKVHYHVPEMRRIKNIHFVGIGGAGMGGIAEVLLNEGYQVSGSDRQANGMTDRLSGLGATIFFGHQASNVEKANVVVVSSAIDPTNPEVNAANEMRIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTSLIATIFAQAELDPTFVIGGLLNSAGTNARLGSSQYLIAEADESDASFVHLQPMVSVVTNIEPDHMETYQGDFQKMQDTYIDFLHNLPFYGLAVLCIDDPVITQLLPRIKRKYLTYGYSEVADVRATHVKHTFNQSEFTLKRKDHQDIQVVVNAPGKHNVLNALAAIAVATDENIEDAAITAALANFSGIGRRFEMLGEFATGEGDVLLVDDYGHHPTEVEATIAVARNNWPDRRLVMAYQPHRYSRTRDLYEDFVRVLSQVDVLLLLDVYSAGEEKIEGADSKSLCRSMRQRGQLEPIYVADKNELPKLLADNLKDQDILLTQGAGNIGQIAKELQEMKLDKGALRTGWSK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB1_CORGL
Sequence: MQKLIQGLGVGAGAALGVCVRLALTLWLGDSAWPILTINVLGAFLMGWLRPNAFWGTGFLGGFTTFSAMMLNDVSFYFFTAVGCILAWLAGDRLAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_YEAST
Sequence: MGRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S13, S27a, Small ribosomal subunit protein uS15, YS15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPB_AQUAE
Sequence: MELIFEKSKKGRKGYKLPELDVEEVNIKEYLPEEYLREELDFPEVSELDVVRHYTNLSHLNYAVDTTMVPLGSCTMKYNPRINEELVNKKEFLNVHPLTPEEYIQPLLKLVYELKELLKELGGFAEVSLQPAAGAHGELLGLLLIHAYHQDRGNKEKKVVLIPDSAHGTNPASAAICGFDIKVVKSDKKGELDFEDFIKKLDERVAALMITNPNTLGIFERKIKEIAEELHKRDALLYMDGANFNALVGRFKPGEWGVDVMHFNLHKTFSTPHGGGGPGAGPVGVSERLKPYLPVPQIEYDGKKYYLNWNIEKSVGKILAFHGHFLVWLKALAYILTYGKDIKKVSEYAVLNARYLKHLLKGVFKDPYPESPCMHEFVLSATNLTKYGVRASDVAKRILDYGFYAPTMYFPLIVREALMIEPTETENPDTLKKFALILRKIVKEAKEKPEILKKAPHRTPVRRIKEAEANRNLILKFKDIKE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: GGGPS_METAC
Sequence: MQVEAHLQKIIDQDGKVHLTLIDPASQTPERAAEIALAAVEGGTDAIMIGGSTGASGTLLDETVIKIKEKVNVPTILFPGSSAGLSSYADAVFFMSLLNSRDLGYVITNQVLGAPLVYKSQIEPISMAYLVVEPGGTVGWVGDAKLIPRKKPDIAAVYALAGKYLGMHYTYLEAGSGADAPIPPEMIGAVKKVLGENKLIVGGGVRDAKTAKLCASAGADMIVTGTIVEEVKDVAAKVAEIVSAIKS
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS1_PHYDS
Sequence: GLWSKIKAAGKEAAKAAAKAAGKAALNAVSEAV
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacteria S. aureus and E. faecalis, and the Gram-negative bacteria P. aeruginosa and E. coli.  Has antiprotozoal activity against T. cruzi.  Has antifungal activity against the yeasts C. tropicalis (MIC=10. 1 uM), C. guilliermondii (MIC=20. 3 uM), C. albicans (MIC=20. 3 uM) and C. albicans ATCC 1023 (MIC=10. 1 uM).  Decreases viability of murine peritoneal cells.  Fuses to, and disrupts liposomes.
What are the official names of this protein?
Dermaseptin-DI1, DRS-DI1, Dermadistinctin-K, DD-K.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.