PharMolix/UniProtQA huggingface dataset:
Protein: DCUP_SYNJA
Sequence: MSHSPAQLSASPSSVGDGDRLLRAARGEVVDRPPVWMMRQAGRYMAAYRELQSKYTFKQRCEIPELAIEISLQPFRAFAPDGVIMFSDILTPLEGMGIPFELVEQQGPIIDPPIRSQAQVEQIRLLEPEESLPFIKTILSTLRREVEGKATLLGFVGSPWTLACYAVEGRSSKDYAHIKSLAFTQPQVLHQLLSKLADSIARYVIYQIECGAQVVQLFDTWAGQLSPGDYETWALPYQKQIVDQVKARCPQVPLILYINGSAALLERVGKAGIDVFSLDWMSDMAEARARLGSLAVQGNLDPMVLLGSPKFIRQRTLEVIQKAGSRGHIMNLGHGVHHTTPEANVHHFFETVRQAAELLKAL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB11_CAEBR
Sequence: MNAPAAFESFLLLDDKKIYIEKDTKVPNAAIFTINKEDHTLGNMLKIQLLKDPEVLFAGYKNPHPLEHKILLRVQTTNATTPADALTTAITDLVGELSLLEHRIDSAIKKCTQSTDTERGYN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB11 is part of the core element with the central large cleft (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase II subunit RPB11, RNA polymerase II subunit B11, DNA-directed RNA polymerase II subunit J.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HMUV_SALRD
Sequence: MIALRDITVHIGDATLIERVSAAVRPGQMTAVVGPNGAGKTTLLRVASGELTPSEGAVQLDDRPLAALSEQAQARRRAVLPQASRLHFAFSVLEVVLMGRTPHVQGREGPEDWAIAEDALDAVAMAGFADRDVPTLSGGEQQRVHLARALAQIWTPPDDGHRYLLLDEPTASLDLAHQQNVLRTARAFADQGAGVLAILHDLNLAAQFADHVVVMADGGVHAQGAPASVLTPPCIREVFGWPVCVLAHPTQSCPLIVPDGAEAGATVSDPNSL
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MTNN_ECO24
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: OPGG_VIBC3
Sequence: MIRVSSAVQRHAQKLIVLFSLLFGASLLMSDNGFATDIKNTNASSPVNSESTKPTKAGEVKNVVRFAKTGSFDNDTVVRLARQLAKKPYVALKDPLPESLANISYDEYRDIRFKPDSAVWKADGLPYQMQLFHRGFFFQDLIEIALVEGNQATHLSYDPNMFTAGEVLQQNLPTEDIGYSGLRVHYPLNSPSYFDELFVFQGASYFRALGKGNAYGLSARGLAIKTADPAGEEFPIFRAFWVEKPNYDTNLIVVHALLDSPSVSGAYRFSIRPGENTRMDVEAVLFPRVELSKVGLAPATSMFMHSPNGREKTDDFRPSVHDSDGLLMINGRGERLWRPLANPSTLQVSAFMDNSPQGFGLMQRERDYANYQDLEAHYEKRPSLWVEPVGNWGPGAVVLTEIPTQSEIHDNIVAFWKPAQPLAAGSEYRFSYHLNWGAQPEANPQAITVSRTASGRADIAKPTPKRLFVIDYQVQGAKPAQMPEPKVRSNAGVISNVVLRDNPANNGYRLSFEFDPGEVTLAELRAELTLQEARPVETWLYRWTL
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MRAY_RHORT
Sequence: MLYFLSELTAQVSALNVFRYLTFRTGGAVMTAMLVAFVFGPGIIEWLKRKQGEGQPIRSDGPESHLTKKGTPTMGGIMILLGVGVATLLWADLSKGYVWAVLLLTLGYGAIGFADDYLKLTKRNTKGLSGRLKLVAQVGMAVIAGLWIMLLGQGDQASSLALPFFKDLTFNLGWFYLPFAAFVMVGASNAVNLTDGLDGLAIVPVMIAAGVFMLIAYLVGNIIFSNYLQIQHVPGTGELAVFCGAIVGAAVGFLWFNAPPAMVFMGDTGSLALGGALGAVSVVTKHEIVLAIVGGLFVLETVSVIVQVASFKLTGKRVFRMAPLHHHFEKKGWAEPTVVIRFWIIAMILAIVGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVA_STAAN
Sequence: MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIRTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAMLALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL5_PECAS
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFLERLISIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDDEGRALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MTA_THECR
Sequence: MDPCECSKTGTCKCGDSCKCTNCSCTTCKKSCCPCCPSGCTKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein A, MT-A.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: DYM_HUMAN
Sequence: MGSNSSRIGDLPKNEYLKKLSGTESISENDPFWNQLLSFSFPAPTSSSELKLLEEATISVCRSLVENNPRTGNLGALIKVFLSRTKELKLSAECQNHIFIWQTHNALFIICCLLKVFICQMSEEELQLHFTYEEKSPGNYSSDSEDLLEELLCCLMQLITDIPLLDITYEISVEAISTMVVFLSCQLFHKEVLRQSISHKYLMRGPCLPYTSKLVKTLLYNFIRQEKPPPPGAHVFPQQSDGGGLLYGLASGVATGLWTVFTLGGVGSKAAASPELSSPLANQSLLLLLVLANLTDASDAPNPYRQAIMSFKNTQDSSPFPSSIPHAFQINFNSLYTALCEQQTSDQATLLLYTLLHQNSNIRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSNDVPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQAGAELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFTMDSD
What is the function of this protein?
Necessary for correct organization of Golgi apparatus.  Involved in bone development.
What are the official names of this protein?
Dymeclin, Dyggve-Melchior-Clausen syndrome protein.
What is the protein family that this protein belongs to?
Belongs to the dymeclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Membrane; Lipid-anchor. Note=Sequence analysis programs clearly predict 1 transmembrane region. However, PubMed:18996921 shows that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol.
Protein: RR8_OSTTA
Sequence: MVNDTISDMLTRLRNAYLADKEQTSLKATRVVKDIAQVLVQEGFLGPIEQEENGFFTVNLKRGVKQFERVSTPGVRVYANHKQLQPVLNGMGVAVISTSQGIMTDRKARALGIGGEVLCKIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AGLR_HALVD
Sequence: MAKLARASALQFGANVTQTFVGAIITIYVINELGVGAFGIFALSAALVKWASIPAVGIRGAVITRMNESDDISPSEYFTTASVLTGAIILVGLLALLGYSPFVEQYLDYSGTQLVGGMFVSNVSFRLVLGGLRGENRVEMSSLYEALWGILSSLVKLALVYTGVGVDALFYGEITSSIVIGIFGVYSLNISFVSPTRSAAISLYSWARYGWLDNLKRMSYSWLDTIILGFFVSTSLVGIYEVAWRISALFVLLPTAISKSTFPTISSLRDTDKLNKVRRILTRGLSVAGVLAIPGLVGSVLVGGDILALYGPSVSSVGVAVSVLVSLSVVRLVECYETLVMQALNALDLPDRTFRIGVIFITTNIILNVSLIPMFGVIGAAIATLLSMTLGSILAVRALPKAVQTLPPVSAIGSQFVSAGAMAVVLFTILNYRPIGQPIEVVLYVLAGATTYGFVLLSLSSNFRERVQQLLSESLG
What is the function of this protein?
Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins.  Probably mediates or contributes to the translocation of the dolichol-phosphate-mannose across the membrane.
What are the official names of this protein?
Probable flippase AglR, Archaeal glycosylation protein R.
What is the protein family that this protein belongs to?
Belongs to the AglR/Agl15 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAL_XANOM
Sequence: MTASPSKLAQLRELSVVVADTGDYDAIKRLQPVDCTTNPTLVKKALDLPVYADLLERELAWGRAHGGDDRTTTVDEVADRLTIGVGVKLSALVPGRVSTEVDADLAHDTQATIAKARKFVAMYAERGVPKDKILIKIAATWEGIEAARQLQLEGIDCNLTLIFNRAQALACAEANVFLISPFVGRILDYYVAQGQTPASIDEDPGVVFVRTVYNAFKQRGSSTVVMGASFRSTAQIEALAGCDRLTISPDLLEKLDAEHGELPRKLSPGNANNAQITPIDSDSFASGLAADPMATEKLVSGIDTFAKDLHALRKTIADKLAG
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_VIBVU
Sequence: MAEAAPQDTQQHFAIQRIFLKDVSFEAPNSPVMFQKEWNPDVKLDLDTQSRELGEGVYEVILRLTVTVKNAEETAFLCEVQQGGIFTAEKMEAGQLAHCLGAFCPNILFPYARETISSLVVKGTFPQLNLAPVNFDALFMNYLQQQAAQQGAEQA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMCR8_MOUSE
Sequence: MISAPDVVAFTKEDEYEEEPYNEPALPEEYSVPLFPYASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSKASECLKMGNRKAFAGELEKKLKDLDYTRTVLHTETEIQKKANDKGFYSSQAIEKANELANVEKSIIEHQDLLRQIRSYPRQKTKIPDLQPGDTEHTQDQADQVSTTSNPEESANADLYTCRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTQTLAQLSHIEHMFRGDLCYLLTSQIDRVLRKQQPITNFLFEDFVEVDDRMEKQENVPSQPSQDRLPPKPVEECPIPKVLISVGSYKSSVESVLIKMEQELGDEEYTGVEATEARSFDPQENLDYLDMDMKGSISSGESIEVLGTEKSASVLSKSDSQASLTVPLSPHVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEEAYADNEGAIHFQASAGSPEPDETQEGNLENIPSQIDSSCCIGKESEGHLVPLPTPAYTLSDEDSVVSIPPQRYIQKDQGLHVDFGVENTDPSPRDNSCEMFPAYELDPSCLLASRDVSKMSLDNYSDTTSYMGSAASTSSDRIPSAPPAGLSSERHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDETIVRKLVTALSIFVPNYGCYAKPVKHWISSPLHIMDFQKWKLIGLQRVASPANVGTLHTLSRYSRYTSILDLDSKTLRCPLYRGTLVPRLADHRTQIKRGSTYYLHVQSMLTQLCSKAFLYTFCHHLHLPAHSEETQEAVASRQTSFLKLNLGLVNEDIRVVQYLAELLKLHYMQESPGTTHPLLRFDYVPSFLYKI
What is the function of this protein?
Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27617292).  In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (By similarity).  The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ULK1/ATG1 kinase complex and inhibiting its protein kinase activity (PubMed:27617292).  As part of the C9orf72-SMCR8 complex, stimulates RAB8A and RAB11A GTPase activity in vitro (By similarity).  Acts as a regulator of mTORC1 signaling by promoting phosphorylation of mTORC1 substrates (By similarity).  In addition to its activity in the cytoplasm within the C9orf72-SMCR8 complex, SMCR8 also localizes in the nucleus, where it associates with chromatin and negatively regulates expression of suppresses ULK1 and WIPI2 genes (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange protein SMCR8, Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SMCR8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Presynapse. Postsynapse. Note=Localizes mainly in the cytoplasm.
Protein: CH10_STAA8
Sequence: MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_ANASK
Sequence: MKKADAPARARELRDRIRAADHAYYVLDQPLLADAEYDRLMHELQALEADHPELVTADSPTQRVSGAPSERFERVVHREPMLSLGNVQSDDELQEFDARVRRLLGLPDGEPVGYVVEPKLDGLAVELVYRDGAFTSGSTRGDGVNGEDVTANLRVVGGLGANRGVPHALEGRPPPRVEVRGEVLLFKEHFEAMNRQLVRAGEAPFANPRNAAAGTLRQLDWRVTARRPLSFIAYEALLPGDDPWRTHWEKLEELAAWGFETNAENRRCRGLAEVLAYRDRMAERRFELPYDTDGIVVKVDDLDWRRRLGAASKFPRWAVAFKYPPQEEATRIRRIWASVGRTGVLTPVVDFDPVRLSGAMVARATLHNEDEMRRKDILEGDWVLVRRAGEVIPEVVKPLPERRTGAEQPFRFPAECPVCGARVVREEGEKVYRCTGAACPAQLVGRLCHFAQRRALDIEGLGEKLAAGLVERGQVKDFADLYAVPFEVWQQLFSRPRKEQDAGAARELPEKSAQNMVAALERSRKTTLRRFLFALGIPQVGEATAATLARHFGGLARVMDADEEALKGVRDVGPETAAEIRAWTQEPQNRRVVERLLAAGVTPEAEVVEARGPFAGKTVVLTGGLSTMSRDDAKAEIERRGGRVSGSVSRKTDLVVAGEDAGSKLEKARSLGVRIAGEEEFVRLLKE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: HRCA_CORGL
Sequence: MSATEKRRYEVLRAIVADYIASQEPVGSKSLLERHKLNVSSATIRNDMSVLESDGFIVQEHASSGRVPTERGYRLFVDSIHDIKPLSLAERRAILGFLEGGVDLEDVLRRSVQLLSQLTHQAAVVQLPTLKTARVKHCEVVPLSPMRLLLVLITDTGRVDQRNVELEEPLAAEEVNVLRDLLNGALGEKTLTAASDALEELAQQAPTDIRDAMRRCCDVLVNTLVDQPSDRLILAGTSNLTRLSRETSASLPMVLEALEEQVVMLKLLSNVTDLDQVRVHIGGENEDIELRSATVITTGYGSQGSALGGLGVVGPTYMDYSGTISKVSAVAKYVGRVLAGE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: FLAA_TREPA
Sequence: MKKAVVLSAVALLSGVCAVADESVLIDFAKLNADIMADKSGGMTHNRRTVLDYASLADTSYTDEQKALMRSSLAVAQWEVVLNSSARNPVAHAASRVIEAPVSEGAKSFAGERVLGVRVLFPTWDSNANAMIKPAFVIPAYEVMAQVDDQGNVQAPTEEEKASGKGRFEDGYGVVKNVGVLKSIAVNTYGMNYPHGLYVMMRDQDGEVHRYFMGYLLFDSWKELVWNNPSYISDVRSREVRLYPVYPASTPHVVFEGFMVTRDAAHAGGDYVGYFKDVKIIYDKAVLSTVRDFADEDLWGIQARREAERKRVEVARFGQQQVLRYIEQEKLATEVGFTPSGGAQRQEEQQ
What is the function of this protein?
Component of the outer layer of the flagella.
What are the official names of this protein?
Flagellar filament outer layer protein, Sheath protein.
What are the subcellular locations of this protein?
Periplasmic flagellum. Periplasm. Note=Antibody labeling only occurs after mild detergent solubilization (PubMed:25825429).
Protein: THIM_ECO45
Sequence: MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLALGASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMSAAVEQATRSQTPWTLDPVAVGALDYRRRFCVELLSHKPTAIRGNASEIMALAGVANGGRGVDTTDAAANAIPAAQTLARETGAIVVVTGEVDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTLENIASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: ATPF3_SYNP2
Sequence: MLIDWFTVFAQILNFVILLGLLRWFLYKPILQVMAKRQAQLAEQWQTATDLQAQAHQALEQYHQEQQSLQAQRASFLAAARAAADEERQRQLLTLREDIQAQREAWEADLHQEQRAFFHTLRQQVSQQVVAIARQALRDLANATLEQQVVARFCEQLQHLSPAQRQQINHLETPPEAVFIRTAFPLDVTHQAQIKQSLATTLELDGTPIHFVTVPELGCGIELKLAGQEIVWGLDPYLDQLEQTLAIATR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ARNC_ECODH
Sequence: MFEIHPVKKVSVVIPVYNEQESLPELIRRTTTACESLGKEYEILLIDDGSSDNSAHMLVEASQAENSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYGCMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREFGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPE_XANC8
Sequence: MDALALMSASNPAWSAWPAPAKLNLFLQIVGRRADGYHLLQTVFRLLDWGDTVHVRLRTDGQIQRIGASLPGVAEDDDLMVRAARALQIHAGTALGAELRVDKRIPAGGGFGGGSSDAATVLVALNALWGLGLPVDTLAELGLRLGADVPVFVRGHNAWAEGVGEKLTPISLPQAAYVLVDPGIHVPTPVLFQSQELTRDAAPAKIADFASGSLLDNAFEPVLRRREPAIEAVFQALSRIGTPRLTGSGSGCFVEFATRAAAEQAMAHLPGNLRAWVVEGAAHSPLLDALDAIQV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SKA2B_XENLA
Sequence: MNSALPEDVKNLLTELETFLLDVLKAETLSKKGKEKKEILIKRLKDIKHSYPQEFQDKAEDDDQEENDGFPLPPDAVSLASDRDKDEDLPYDGSFYPPVAAQDLEYLKAGYLEKRRKDHSFFASEWQKRWCVFTNSLFYYYGSDKDKQQKGAFSLDGYRAKMNDTLRKDAKKDCCFEIFAPDKRVYQFAASSPKEAEEWINAIMNSRGIIATEDEELYDDVNQEIDASLEEDIYEELPEESEKPVTETETQKATPVPVNNTSGKENTDYANFYRGLWDCTGDHPDELSFKHGDTIYIISKEYNTYGWWVGEMKGTIGLVPKAYIIEMYDI
What is the function of this protein?
May be involved in B-cell and macrophage adhesion processes.  May play a role in src signaling pathway (By similarity).
What are the official names of this protein?
Src kinase-associated phosphoprotein 2-B.
What is the protein family that this protein belongs to?
Belongs to the SKAP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAB_ECOHS
Sequence: MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQEQQINDLPALISATQALPACRFIINPNDDRFINPETMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLYIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVARIHSTRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: RS19_RUEST
Sequence: MTRSVWKGPFVDAYVLKKAEAARDSGRNEVIKIWSRRSTILPQFVGLTFGVYNGQKHIPVNVTEDMIGQKFGEYSPTRTYYGHAADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.