PharMolix/UniProtQA huggingface dataset:
Protein: YCF76_ORYSA
Sequence: MKKILFSMFYSILVGEEPDSVFLKKEGKQNQVKMIWVAPSSCAKDLTISEGTGATFLFNFHSRVSYLFPRPFLRPRNMKWTNSFS
What are the official names of this protein?
Uncharacterized protein ycf76, ORF85.
What is the protein family that this protein belongs to?
Belongs to the ycf76 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRMB_CHLAB
Sequence: MKPQDLKAPFFGEERKTQIKDDVLYIPEHYFKHGQFEMPSWEEFFGNNHPIFCELCSGNGDWVVAQANKNPNMNWIAVEKRFDRVRKIWSKMHNSQVRNLRIVCGEAQTFFRHYIQNEVIQRIVVNFPDPWPKSRHRKHRLFQYEFMNDIVRVLVDSGIIILATDDKNYLLQAIKIMQQRLLPKLEEPYYCKMLENYGDSWFERLWRSKGQEIFYTEFVKKVGI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: AHPC_STAHJ
Sequence: MSLINKEILPFIAQAYDPKKDEFKEVSQDDLKGSWSVVCFYPADFSFVCPTELEDLQNQYDKLQDLGVNVFSVSTDTHFVHKAWHDHSDAISKIQYQMIGDPSQTITRNFDVLDEEAGLAQRGTFIIDPDGVVQAAEINADGIGRDASTLVNKIKAAQYVRQHPGEVCPAKWEEGSESLQPGLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBN_SALTY
Sequence: MELIFLGTSAGVPTRSRNVTAILLHLQHPTQPGVWLFDCGEGTQHQMLNTAFHPGKLERIFISHLHGDHLFGLPGLLCSRSMAGNPHPLTVYGPQGVREFIATTLRLSGSWTDFPLQIEEISAGDILDDGLRKVTAFRLEHPLECYGYRVVEHDKPGALNARALKAAGVTPGPLFQALKAGKTVTLADGRQINGADYLAPAVAGKSVAIFGDTAPCEAALALAQGVDVMVHETTLDASMEEKANARGHSSTRQTATLAREAAVGRLIMTHISSRYDDKGCQRLLAECRAIFPATELAYDFSVFPV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: OTC_BURPS
Sequence: MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWVGDANNMLYTWIQAARILGFKLRLSTPPGYALDTKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQAFADWCVDEEMMSHAHPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLNH
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISDE_STAAN
Sequence: MRIIKYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALTMTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLNINPDIILRLPHGMPEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDADKAMTQLYDLFYKDKK
What is the function of this protein?
Involved in heme (porphyrin) scavenging.  Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme.  Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors to the probable permease IsdF (By similarity).
What are the official names of this protein?
High-affinity heme uptake system protein IsdE, Iron-regulated surface determinant protein E, Staphylococcal iron-regulated protein F.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 8 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SDCG8_HUMAN
Sequence: MAKSPENSTLEEILGQYQRSLREHASRSIHQLTCALKEGDVTIGEDAPNLSFSTSVGNEDARTAWPELQQSHAVNQLKDLLRQQADKESEVSPSRRRKMSPLRSLEHEETNMPTMHDLVHTINDQSQYIHHLEAEVKFCKEELSGMKNKIQVVVLENEGLQQQLKSQRQEETLREQTLLDASGNMHNSWITTGEDSGVGETSKRPFSHDNADFGKAASAGEQLELEKLKLTYEEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAANTCNRVGGLCLKCAQHEAVLSQTHTNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQLPSMPQSDC
What is the function of this protein?
Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity).  Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation.  Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis (PubMed:27224062).
What are the official names of this protein?
Serologically defined colon cancer antigen 8, Antigen NY-CO-8, Centrosomal colon cancer autoantigen protein, hCCCAP.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cell junction. Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: GLGC_RHOP2
Sequence: MSNGVTAPLARHAMAYVLAGGRGSRLMELTDRRAKPAVYFGGKSRIIDFALSNALNSGIRRIAVATQYKAHSLIRHLQRGWNFFRPERNESFDILPASQRVSDDMWYRGTADAVYQNIDIIESYDPKFIVLLAGDHVYKMDYEKMLQQHVEQGADVTVGCLEVARSEATAFGVMHVDAKDVIQSFLEKPADPPAMPGKPDRALVSMGIYVFDTKFLIEELHRDAANPNSSHDFGKDIIPYIVQHGKAVAHHFDKSCRRSHAEDTSYWRDAGTVDAYWAANIDLTDIVPQLDLYDREWPIWTYGEITPPAKFVHDKDGRRGEAVSSLVSGGCIISGAALRHTLLFTGVRVHSYSQVEGAVILPYADIARSCRLKNVVVDAEVRIPDGLVVGEDPELDARRFRRTDSGICLITQPMIDRLDQ
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: AB27_CYPCA
Sequence: GIGGKPVQTAFVDNDGIYD
What is the function of this protein?
Has antibacterial activity.  It inhibits fish bacterial pathogens, A. hydrophila and M. luteus, and also E. coli, P. fluorescens and S. aureus.  Forms large ion channels responsible for disrupting the cellular envelope of bacteria leading to cell lysis.
What are the official names of this protein?
27 kDa antibacterial protein.
Protein: TMCAL_ACET2
Sequence: MKVLGLIVEYNPFHNGHLYHLEESKKISGADFVVCVMSGNFIQRGEPAIVNKWARTKMALSAGADLVIELPLSCAMASAEYFASGAVRILNDIGIVDYICFGSEHGDVKTLDYIAQILVEEPESYKSFLKEELDNGLSYPAARESALKKYTAHSINIPQIISSSNNILGIEYLKALRRIKSSIIPLTIKRINNDYNTENITGSISSASSIRKYISTSNSTSFDDVLAMTMPKTSVDILFEEFSAGRGPVFKEDFYPVVTSLIRKMTPEQIRNFAYVSEGLENRIKSAADTAGTYEELVESICTRRYTKTRVQRILMGILMGVTSKDLDMLSRFDSPQYARILGFNSKGKQLLSQIKKKSSIPLVLKLSDFIKSCDPVLKRKLELEILATDLYVMCYKNPAFRKAGQEFTQNIIIM
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNAS_HOMAM
Sequence: MGCFGSAGAKGDAEENKKRKEANKNINKQIQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSEEEKREKIHAIRCNIRDAILTITGNMSTLTPPIALENPAHQFRVDYIQDVASQKDFDYPEEFYEHTEMLWKDKGVQACYERANEYQLIDCAKYFLDRVHIVRQTDYTPTEQDILRCRVLTLGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPSQNRLRESLDLFKSIWNNRWLRTISVILFLNKQDLLAEKIRAGKSKLEDYFPDFARYQTPLDATVEPGEDPEVVRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli.
What are the official names of this protein?
Guanine nucleotide-binding protein G(s) subunit alpha, Adenylate cyclase-stimulating G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(s) subfamily.
Protein: CAPPA_SULIK
Sequence: MRIIPRTMSTQHPDNAKVPEWAKSEVIEGEDEVKEAFLAYSMYGVHEVMWDAEGKDVDTHVVRKLLSNYPDYFREHILGKDVFLTYRLPNPKVEGADRKVFAETMESIPITYDLAEKFYGNGITVPVFEVILPMTTSNLEIISVARYYEKAVANEDELELYNGVKVKDLVGEIYPKVIEVIPLVEDRDSLQNIDNIVEGYYKVIKPKYMRVFLARSDPAMNYGMITAVLSVKIALSELYKLSESLNFEIYPIIGVGSLPFRGHLSPENYEKVLEEYKGVYTYTIQSAFKYDYDYDKVKSAISSINNSRIGPAKILEKYEEDVLRKITILYTERYQPIIESLANAINDVSVLLPRRRARKLHIGLFGYSRSAGKVSLPRAISFVGSLYSIGIPPELIGISSLSNLDEKEWDIFKQNYVNFKHDLQTAARFFNWESFELIKDIWKISEDTIAKIKEDIDYAESVIGIKLGDIDYDSRKHILMSSLFLLSFKEKILQESKKYLYEMALIRRSLG
What is the function of this protein?
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 2 family.
Protein: RHP9_SCHPO
Sequence: MEVNDTSLHKGFGLDINSQRVFGAQAAISRNNYSKVNASINPSPPRSNDNSNKEFSYSKDVNNNGAVEELSLTQLFEVPSQAAFAKQSSQDISDDELIQHDSRKVISSPYSPKQTHTVLKRLYDRQSVISDHEKLLTPQNVSNSSQILSPFTSLLPSTLSTLKDTPLSVSQNEKNLETVGEVLVPETVAQHRTKFYDYTLDEMENETESGQVETTPTRLATSLGSPVLYGRVESTPPAFLPETSEKQYKRKFSFTEPSSEKVDNTETKFSKKTKNINDENFPNPFNVISSYETSASPSTVIDQSSQVSSIFVNKRLRKSVNNQAISRSDSLSLDTPKIDSLFTRASIKPLKPSQSPNSRRSFKNRVLAFFKGYPSFYYPATLVAPVHSAVTSSIMYKVQFDDATMSTVNSNQIKRFFLKKGDVVQSTRLGKIKHTVVKTFRSTNEQLSLIAVDALNNDMVILAHGEIEVTVPISTIYVAPVNIRRFQGRDLSFSTLKDMKFEETSFLPSHDSQRNRSSLKERDSSFVKKNLDSESNQLIFDDCVFAFSGPVHEDAYDRSALETVVQDHGGLVLDTGLRPLFNDPFKSKQKKLRHLKPQKRSKSWNQAFVVSDTFSRKVKYLEALAFNIPCVHPQFIKQCLKMNRVVDFSPYLLASGYSHRLDCTLSQRIEPFDTTDSLYDRLLARKGPLFGKKILFIIPEAKSWQKKIENTEQGQKALAHVYHALALGADVEIRPNVAHLECDLILTMDGNIVDETNCPVVDPEWIVECLISQSDIST
What is the function of this protein?
Essential for cell cycle arrest at the G1 and G2 stages following DNA damage by X-, and UV-irradiation, or inactivation of DNA ligase.  Plays a role in the response to DNA damage (PubMed:9153313, PubMed:9407031).  Interaction with rad4 via its phosphorylation sites in the N-terminus couples the DNA checkpoint apparatus to chromatin via interaction of its C-terminal BRCT domains with epigenetic modifications on histones H4 and H2A, respectively, in the G1/S phase of the cell cycle, and facilitates recruitment of the checkpoint kinase chk1 (PubMed:15550243, PubMed:16778077, PubMed:18826944, PubMed:20679485, PubMed:22792081).
What are the official names of this protein?
DNA repair protein crb2, Checkpoint mediator protein crb2, Cut5-repeat binding protein 2, RAD9 protein homolog.
Protein: Y1433_MYCBO
Sequence: MKRTNIYLDEEQTASLDKLAAQEGVSRAELIRLLLNRALTTAGDDLASDLQAINDSFGTLRHLDPPVRRSGGREQHLAQVWRATS
What are the official names of this protein?
Uncharacterized protein Mb1433c.
Protein: MGRB_ECOL5
Sequence: MKKFRWVALVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIP
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYA_PSET1
Sequence: MQHMTTAQIRQQFLDFFASKQHQVVPSSSLIPGNDATLLFNNAGMVQFKDVFLGAESRPYTRATSSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKQDAIKFAWQFLTEEVKLPKEKLLVTIYHDDEEAFNYWSNDIGLPADRIIRIATADNFWSMGDTGPCGPCSEIFYDHGEHIWGGPPGSPEEDGDRFIEIWNLVFMQYNRQNDGTMLPLPKQSVDTGMGLERIAAILQGVHSNYEIDLFKGLIAAAASVTNAQDMDDKSLRVVADHIRSCAFLISDGVMPSNEGRGYVLRRIIRRAVRHGNKLGAQGAFFYKLVAALIEQMGQAYPELAKQQEIIEKVLRIEEEQFGKTLERGLAILEESLSDLKGDVIPGDLVFKLYDTYGFPADLTADVARERQMTIDNKGFEECMAVQRKTAQQAGKFGADYNDQLKSDKQTTYKGYTTTSHSATVVEVFAGSESVSLLEDGQKGIVILDRTPFYAESGGQVGDTGVISVAGGEFTVTNTTKLGNAFAHHGIVQGRIGLNDKVEATIDDARRERIKKNHTATHILHETLRQLLGEHVGQKGSLVQAERLRFDFSHFEAVTKEELREIERVVNDEIRCNFALSTELMAIDDAKAKGAMALFGEKYDDEVRVVTIGDYSIELCGGTHVERAGDIGLFKIVSESGIAAGVRRIEAVTGADAIAYVSEQEQKLNDVAAVVKADSASVLEKVTALLDKSKQLEKQIAQLNDKLASAAGASLLDSVVEINGIKLLIANVKGTESKALRGMVDDLKNKIGSGVIALGVASDDKVSLIAGVTKDLTGRVKAGELVNHMASQVGGKGGGRPDMAQAGGSEPENLTAALDSVTAWFTEKTQA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_SHIDS
Sequence: MIREECLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SSUD_PSEPU
Sequence: MSLNIFWFLPTHGDGKYLGTSEGARAVDHGYLQQIAQAADRLGFGGVLIPTGRSCEDSWLVAASLIPVTQRLKFLVALRPGIISPTVAARQAATLDRLSNGRALFNLVTGGDPDELAGDGLHLNHQERYEASVEFTRIWRKVLEGEVVDYDGKHIQVKGAKLLYPPIQQPRPPLYFGGSSEAAQDLAAEQVELYLTWGEPPSAVAEKIAQVREKAAAQGREVRFGIRLHVIVRETNEEAWAAADKLISHLDDDTIARAQASLARFDSVGQQRMAALHNGNRDKLEVSPNLWAGVGLVRGGAGTALVGDGPTVAARVKEYAELGIDTFIFSGYPHLEESYRVAELLFPHLDVQRPEQAKTSGYVSPFGEMVANDILPKSVAQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.  Seems also to be involved in the desulfurization of aromatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: NUOK_BACC4
Sequence: MSSVPASAYLTLAIILFCIGLFGALTKRNTVIVLVCIELMLNAANLNLVAFSKLGLFPNLTGQIFSLFTMAVAAAEAAVGLAILIALYRNRTTVQVDEMDTLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROB_PSEA8
Sequence: MRTLHVDLGERSYPIYIGENLLGDARWFAPHIVGRRVAVISNETVAPLYLETLLKALQGHEVTPVVLPDGEAYKQWETLQLIFDALLKERHDRKTTLIALGGGVIGDMAGFAAACYQRGVNFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVVIDTASLKTLPSRELSAGLAEVIKYGFICDEPFITWLEEHMDALLALEPTVVTEAIERSCAAKARVVGADERELGVRATLNLGHTFGHAIETQQGYGVWLHGEAVGAGTVMALEMSHRLGWLSAAERDRGTRLLRRAGLPVVPPAEMTAEDFMEHMAVDKKVLDGRLRLVLLQGLGNAVVTGDFPREILDATLRTDYRALADQLGDE
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_HAHCH
Sequence: MATVVGFDFGLKRFGAAVGQSVSMTASPLKEIPAQDGIPRWEAIEALLEEWKPALVIVGEPLNMDGSVSEMALRARKFARRLHGRYNLRVEMADERLTSSEAKSMVRERYGQRDFGRFAVDSIAAVFIVESWLEAHADNLDAFLHPPRKQGKSNDIID
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATA2_BPQBE
Sequence: MPKLPRGLRFGADNEILNDFQELWFPDLFIESSDTHPWYTLKGRVLNAHLDDRLPNVGGRQVRRTPHRVTVPIASSGLRPVTTVQYDPAALSFLLNARVDWDFGNGDSANLVINDFLFRTFAPKEFDFSNSLVPRYTQAFSAFNAKYGTMIGEGLETIKYLGLLLRRLREGYRAVKRGDLRALRRVIQSYHNGKWKPATAGNLWLEFRYGLMPLFYDIRDVMLDWQNRHDKIQRLLRFSVGHGEDYVVEFDNLYPAVAYFKLKGEITLERRHRHGISYANREGYAVFDNGSLRPVSDWKELATAFINPHEVAWELTPYSFVVDWFLNVGDILAQQGQLYHNIDIVDGFDRRDIRLKSFTIKGERNGRPVNVSASLSAVDLFYSRLHTSNLPFATLDLDTTFSSFKHVLDSIFLLTQRVKR
What is the function of this protein?
Induces host cell lysis (PubMed:11892805, PubMed:29078304).  Inhibits host MurA activity thereby blocking the synthesis of murein precursors necessary for the host cell wall biosynthesis (PubMed:11423662, PubMed:29078304).  May be responsible for the attachment to the host pilus.  Makes extensive contacts with the viral genome (PubMed:28111107).
What are the official names of this protein?
Maturation protein A2, MP, A2 protein.
What are the subcellular locations of this protein?
Virion. Note=A single copy of the maturation protein is present in the virion.
Protein: ESPI_MYCTO
Sequence: MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTPPPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTPPMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQLAPPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEPPPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQRNSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSLRPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEKYELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRILALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLEVLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVLSTVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRACVVINHIMPGEPNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVLELAAALSDDFERAGRR
What is the function of this protein?
Required to repress ESX-1-mediated secretion under low ATP conditions.  This function requires the ATP-binding motif.
What are the official names of this protein?
ESX-1 secretion-associated protein EspI.
Protein: PGK_HYPJE
Sequence: MSLSNKLSITDVDLKGKRVLIRVDFNVPLDENKKITNNQRIVGAIPTIKHALDNGAKAVVLMSHLGRPNGAVNPKYSLKPVVPELERLLGKPVTFARDCVGPEVESIVNDADNGAVILLENLRFHIEEEGSAKDKDGNKTKADKAKVEEFRKGLTALGDIYINDAFGTAHRAHSSMVGVDLPQKAAGFLMKKELDYFAKALESPQRPFLAILGGAKVSDKIQLIDNLLDKVDTLIVCGGMAFTFKKVLNNIPIGTSLFDEAGAKTCPSCREAKAKNVKLVLPVDYITADKFDKDANTGTATDESGIPDGWMGLDCGEKSIELYKEAIADAKTILWNGPAGVFEFDKFANGTKATLDAVVEGCKNGKIVIIGGGDTATVAAKYGVEDKLSHVSTGGGASLELLEGKELPGVVALSSK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOG1_USTMA
Sequence: MADFVKLSIFGTVFEVTTRYVDLQPVGMGAFGLVCSANDQLTSTSVAIKKIMKPFSTPVLSKRTYRELKLLKHIRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVAVDVWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDEVIKTICSENTLRFVQSLPKRERVPFSQKFKNADPMALDLLEKMLVFDPRTRISAAEALAHPYLAPYHDPTDEPEAEEAFDWSFNDADLPVDTWKVMMYSEILDFHNIDNSGQDEGPVPPVNN
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase HOG1, MAP kinase HOG1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GPC5B_MOUSE
Sequence: MFLVLERKMRTHQVFPLPLLLVIASVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKDKERKRPVCLHFLFLLGTLGLFGLTFAFIIQMDETICSIRRFLWGVLFALCFSCLLSQAWRVRRLVRQGTSPASWQLVSLALCLMLVQVIIATEWLVLTVLRDTKPACAYEPMDFVMALIYDMVLLAITLAQSLFTLCGKFKRWKVNGAFILVTTFLSALIWVVWMTMYLFGNSLIKQGDAWSDPTLAITLAASGWVFVIFHAIPEIHYTLLPPLQENPPNYFDTSQPRMRETAFDEEMHLPRAYMENKAFSMDEHNAALRSAVGFSNGSLEQRSSSLGKKPSSLGNRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHHW
What is the function of this protein?
Unknown.  This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways (By similarity).
What are the official names of this protein?
G-protein coupled receptor family C group 5 member B, Retinoic acid-induced gene 2 protein, RAIG-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDHG_SOYBN
Sequence: MEANSGASDRISRIAGHLRPQREDDVCLKRSDCRAKGGVSGFKVAILGAAGGIGQPLAMLMKMNPLVSLLHLYDVVNTPGVTSDISHMDTGAVVRGFLGQQQLEDALIGMDLVIIPAGVPRKPGMTRDDLFNINAGIVKTLCEAIAKCCPKAIVNVISNPVNSTVPIAAEVFKRAGTYDPKRLLGVTMLDVVRANTFVAEVLGVDPRDVDVPVVGGHAGITILPLLSQIKPPCSFTPKEIEYLTGRIQNGGPEVVEAKAGAGSATLSMAYAAVKFADACLHALRGDAGIIECAYVASQVTELPFFASKVRLGRVGVEEILPLGPLNDYERESLEKAKKELAASIEKGISFIRK
What are the official names of this protein?
Malate dehydrogenase, glyoxysomal.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: RUVA_TRIV2
Sequence: MISYLKGIVAGIQNVGSNRVILTLEVNGMGYDLQIPQRLAKQLPTTGDLVQIFTHYQVREEIPLLYGFSSPAERDLFRHLLSVSGVGAASAIALLDTLELPDLVQAIIAANVQILIQAPGVGKKIADRICLELKAKLIEWRKSAGFFVATEGPAPGILEEVQMTLFALGYTAHEVSHALHVVSEDIGLPKDAYVEDWIKQAIAHLSSSEQVSH
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.