PharMolix/UniProtQA huggingface dataset:
Protein: EHD1_ARATH
Sequence: MEIESVAAGSCSKENQMIYKEWFEFSDSDGDGRITGNDAIKFFTMSNLPRPELKQIWAIADSKRQGYLGFKEFIVAMQLVSLAQTGHEISHEVLISDVDFKNINPPTMEGLGVLMAKKKHSSKSSDPNMNGSPAADTSLTAHWFSSKSSKKISLSSVTSIVDGLKRLYIQKLKPLEVAYRFNDFVSPLLTNSDFDAKPMVMLLGQYSTGKTTFIKHLLKSTYPGAHIGPEPTTDRFVVVMSGPDERSIPGNTVAVQADMPFSGLTTFGTAFLSKFECSQMPHPLLEHVTFVDTPGVLSGEKQRTQRAYDFTGVTSWFASKCDLILLLFDPHKLDVSDEFKRVISSLRGHDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVLNTPEVSRVYIGSFSDKPINEAATGPIGRELFEKEQDDLLADLKDIPKKACDRRINEFVKRARAAKIHAYIISHLKKEMPAIMGKAKAQQKLIDNLEDEFGKVQREHHLPKGDFPNVDHFREVLSGYNIDKFEKLKPKMLQTVDDMLGYDIPELLKNFKNPYD
What is the function of this protein?
Involved in endocytosis positive regulation.  Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed:18547399, PubMed:23342166).  Confers salt tolerance (PubMed:23342166).
What are the official names of this protein?
EH domain-containing protein 1, AtEHD1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: ISPH_CAMJR
Sequence: MIIELAKNYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEISRLQKNFNVKTLENIQALSNEKKAIIRTHGITKQDLEELRKKDIEIFDATCPFVTKPQQICEQMSKEGYEVVIFGDENHPEVKGVKSYVSTKAYVVLDKKELQNIKLPNKIAVVSQTTKKPEHFMEIVNFLILKTKEVRVFNTICDATFKNQDAIKELSLKSDVMVVVGGKNSANTKQLFLIAKTNCEDSYLIETEEELKKEWFLDKKHCGISAGASTPDWIIQKVIAKIENFKIN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: CYB_CROSH
Sequence: MTNIRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLIAQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIVAALAGVHLLFLHETGSNNPSGLNSDTDKIPFHPYYTIKDILGALIMISTLSSLVLFSPDMLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMIIPLLHTAKQRSMMFRPMSQCMFWILVADLFTLTWIGGQPVEYPFVVIGQLASVFYFLIILFIMPVTSMIENQLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PHIP_MOUSE
Sequence: MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPTKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSSGLNQVLSQQANQDISPLDSMIQRLQQEQDLRRSGEAGVSNASRVNRGSVSSTSEVHSPPNIGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRKHLTVAKENKILTVSKNHAHEHFLDLGDSKKQQANQHNYRTRSALEETPRPLEELENGTSSSDEGEVLAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKKPESSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRPWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEEEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCQELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNFKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTISKKRKKRNRSSSLSSSAASSPERKKRILKPQLKSEVSTSPFSIPTRSVLPRHNAAQMNGKPESSSVVRTRSNRVAVDPVVTEQPSTSSATKAFVSKTNTSAMPGKAMLENSVRHSKALSTLSSPDPLTFSHATKNNSAKENMEKEKPVKRKMKSSVFSKASPLPKSAAVIEQGECKNNVLIPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTSSGEVTHKKRGRKPKNLQCAKQENSEQNNMHPIRADVLPSSTCNFLSETNAVKEDLLQKKSRGGRKPKRKMKTHNLDSELIVPTNVKVLRRSNRKKTDDPIDEEEEFEELKGSEPHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW
What is the function of this protein?
Probable regulator of the insulin and insulin-like growth factor signaling pathways.  Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation.  Plays a role in the regulation of cell morphology and cytoskeletal organization.
What are the official names of this protein?
PH-interacting protein, PHIP, IRS-1 PH domain-binding protein, Neuronal differentiation-related protein, NDRP, WD repeat-containing protein 11.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCLL_ARATH
Sequence: MGKEVMVSDYGDDDGEDAGGGDEYRIPEWEIGLPNGDDLTPLSQYLVPSILALAFSMIPERSRTIHDVNRASQITLSSLRSSTNASSVMEEVVDRVESSVPGSDPKKQKKSDGGEAAAVEDSTAEEGDSGPEDASGKTSKRPRLVWTPQLHKRFVDVVAHLGIKNAVPKTIMQLMNVEGLTRENVASHLQKYRLYLKRIQGLTTEEDPYSSSDQLFSSTPVPPQSFQDGGGSNGKLGVPVPVPSMVPIPGYGNQMGMQGYYQQYSNHGNESNQYMMQQNKFGTMVTYPSVGGGDVNDK
What is the function of this protein?
Transcription factor that is a critical component of the regulatory circuit of the circadian clock.  Binds to specific sites on CCA1 promoter leading to CCA1 activation.  Is required for the rhythmic expression of other clock genes such as LHY, GI and APRR1/TOC1.
What are the official names of this protein?
Transcription factor BOA, Protein BROTHER OF LUX ARRHYTHMO, Protein PHYTOCLOCK 1-like, Protein PCL1-like.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPB_RHILW
Sequence: MNETPKPNSFRSGPDEDGRFGIYGGRFVAETLMPLILDLQDEWNKAKNDPAFQAELKHLGAHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGSGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSVIGTEAKEQMLAAEGRLPDLVIAAVGGGSNAIGIFHPFLDDPTVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPGIGPEHSWLNDTGRVDYVPIMDHEALEAFQTLTRLEGIIPALEPSHAIAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGKILGMGL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: EMC89_ARATH
Sequence: MGMGSNGELKYEISQNAYIKLVLHSLRHKTAAVNGVLVGRISPKDDGVVEISDSVPLFHSNLALLPPLEISLIMIEEHYVAQGLSIVGYFHANERFDDVELCGVAKNIGDHISRYFPQAPILLLNNKKLEALSKGKERSPVMQLCVKDASKNWRVVGADGGSKLLLKEPSANVVLSDYISSEKWKDVTDVDDHLDDVTKDWLNPGLFN
What are the official names of this protein?
ER membrane protein complex subunit 8/9 homolog, Protein EMBRYO DEFECTIVE 2731.
What is the protein family that this protein belongs to?
Belongs to the EMC8/EMC9 family.
Protein: RL33_RICM5
Sequence: MAKKNKNVLVRLVSTAGTGVFWVKKRNPKTQTEKLSFRKYDKVVRKHVLFKEEKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: LOLA_VIBC3
Sequence: MNKWLALLFCSFSAIAAPKDTLSERLAMSEGFSATFNQQVLSPEGKVILTGNGKVDIARPSLFRWETETPDENLLVSDGTTLWHFDPFVEQVTLYRAEEALEQTPFVLLTRNKASDWDAYHVEEKGDVFTLTPTALDSNQGRFQITISEKGVVQGFKVIEQDGQQSEFTFSKVKQQKPNASVFNYKVPKGVEVDDQRN
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SERC_DESAL
Sequence: MKNRIHNFNAGPAALPLPVLEEIQAELLDFKGSGMSIMEVSHRSKWFDDVINETVERINRLMGLGDDFQVLFMQGGASTQFALVPMNLLPEGQSADYVNTGTWSTKAIKEAQAMGKTVNVAASSEDRNFCYIPKDIPLDPNAAYVHITSNNTIKGTAYTDFPDAGNVPLIADMSSDILSRPIDASKFGLIYAGAQKNMGPAGVCVAIIRKDMLERVPASLPSMFKYTTFADKNSMYNTPPCFAIYTVGLVVKWIEETIGGLEKMEARNRKKADTLYSIFDSSDFYSGTADKDSRSLMNVTFRLPSEDLEKAFVAQALENGLGGLKGHRSVGGCRASIYNPTSQEGIEALVDFMKEFEKKNG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYTM1_XENTR
Sequence: MNYENPPPYASPPAPYPPYGQQQPSYPVPNQYPGNPPGPVGYQPAQPGYQGYPQYGWQGAPPANAPVYMDAPKNTVYVVEERRNDTSGESACLTACWTALCCCCLWDMLT
What are the official names of this protein?
Cysteine-rich and transmembrane domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CYSTM1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PAM17_CANGA
Sequence: MLSITQGIVRRSVARPGLIRPLVKCNARYYSDKPEDSLTWTDFFQLRKQERRINVGSSVFTALVGANVSWAYLSTMEIDPTQMIFGFDPLVVVTAGLMASGALGYLMGPAVGSQVFKLTKGNKLAQYNLKNKEFLKHVIQNRVDASSQSFSNPVPDYYGEKIGSVKEYRQWLRDCHAYAKKAKEFL
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Presequence translocated-associated motor subunit PAM17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NECT1_MOUSE
Sequence: MARMGLAGAAGRWWGLALGLTAFFLPGTHTQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKASNGSKQNMAIYNPTMGVSVLPPYEKRVEFLRPSFIDGTIRLSGLELEDEGMYICEFATFPTGNRESQLNLTVMAKPTNWIEGTRAVLRARKGQDDKVLVATCTSANGKPPSAVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHRQSLACIVNYHLDRFRESLTLNVQYEPEVTIEGFDGNWYLQRTDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFRGPITYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPTPEHGRRAGQMPTAIIGGVAGSVLLVLIVVGGIIVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV
What is the function of this protein?
Involved in cell adhesion and synaptogegesis.  Has some neurite outgrowth-promoting activity.  Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells.
What are the official names of this protein?
Nectin-1, Herpes virus entry mediator C, Herpesvirus entry mediator C, HveC, Nectin cell adhesion molecule 1, Poliovirus receptor-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Presynaptic cell membrane.
Protein: TRPD_HYPNA
Sequence: MSESALNTAIQAIARGLPLEESVLEGAFDTLLSGEAAPEEVGAFLAGLTVRGETANELIAGARIMRRHGRSVSVEGPLLDTCGTGGLPWKSLNTSTASAIVIAAAGGRVAKHGNRSVPPKTGSADVLEALGLQLELSDTAFKSCLEIAGVGFLFARSYHSAMRHVAPIRHKLGIRTIFNLLGPLSNPAGAEYSVLGVYDKQWVTPMAEALKALGTRCAWVVHGLAGIDEISISGPTDVCEVTPASIRHFQITPSDAGLPSHPLSTLEGGAPEENTAAIRDLLDGREGPFRDIVLINAAAGLHVSGMVADLPAGVQRAAQAIDSGAARETLNTLVRTSRESD
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CHM2B_CHICK
Sequence: MASLFKKKTVDDIIKEQNRELRGTQRTITRDRAALEKQERQLELEIKKMAKTGNKEACKVLAKQLVQLRKQKNRTYAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDASDEEEESQDIVNQVLDEIGIEISGKMAKAPSAARGLPSASTSKASTISDEEIERQLKALGVD
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 2b, Chromatin-modifying protein 2b, CHMP2b.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein.
Protein: OCT5_ARATH
Sequence: MADSLAPLLPTHIEEDEDTSSPLTFDKILEKSLSDFGFSQFLQIVLVGLALTFDSQQIFITVFTDAYPTWHCLDHTICNPATTDICKIPRSAWDWDGGFKGKSVISEFDLECSSSFLRSLPSSTFYVGSIVGGVVLAMIPDGSLGRKQLLFFSSFAMSLTGISIFLSSNIWIYSFLKFVIGFARSQTGTYALVLISERISTKWRPRATMVPFTLFVLGFMSLSGIAYLVRHASWKVLYLCTSIPAGIHSIFIYFFALESPRWLHLEGKNKEAIEVLKRISPANRGYLESVSSRLRPKETLEQTSSYSIKDLFIIKWAFRRVTLVMIIMFGLGMSYYGVPLAVRDIKVNIYMSEALNAMVELPTFVVTPILLEQFSRRSSVLVNCLIGGASGVLCFVMSLYGRTKIAFALELGSFFCARIGFNLMAIYLVELFPTCVRNSATMMLRQALVVGGACCPLIASLGRNVPSLSFAVFGFAMSGLGLFALLLPETKGLSLCDTMEEQEQRDQALKTSHSC
What is the function of this protein?
High affinity carnitine transporter involved in the active cellular uptake of carnitine.  Also transports organic cations (By similarity).
What are the official names of this protein?
Organic cation/carnitine transporter 5, AtOCT5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RLMM_ECOBW
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEPA_STAHJ
Sequence: MKDEQLFYFEESSIFKAMMHFSLPMMIGSLLSVIYGILNIYFIGFLDNSHMISAISLTLPIFAVLMAFGNLFGVGGGTYISRLLGAKDYIKSHYVSSFSIYSSLVLGLIIAVITLPFTDQIASILCASGETLNYTSDYLKIEFLSTPFVILFFVLEQFARAIGKPIISMIGMLSSVGINIILDPILIFGLHLDVVGAALGTAISNAIAGLFFIIYFSRKNETLSFNVKHAKPTKAMMQEIFKIGIPAFLMVVLMGVTGLVVNLFLATYGNYAIASYGISFRLVQFPELIIMGLSEGVVPLIAYNFVSNKTRMKDTIKVVIVSIAVIFAVCMTVVLVAGHSIVQLFSTDPQIVVLATFILKVTMTSLLLNGIGFLFTGMLQATGQGRGATIMAIAQGTVIIPVLFVLNSLFGLTGVIWSLLIAETVCAFLAMFIVYSLRNRLTVDKASLIEVE
What is the function of this protein?
Multidrug resistance efflux protein.
What are the official names of this protein?
Multidrug export protein MepA.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y743_ENT38
Sequence: MRKNTYAMRYIAGQPAERILPPGSFASIGQALPAGAPLSSDEKIRVLVWNIFKQQRAEWLSVLKNFGKDAHLVLLQEAQTTPELVRFATTNYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNFSLGVDVYSKQLLPIGDQIAHHSGPIIMAGDFNAWSRPRMNALYRFAREMSLREVRFTDDQRRKAFGRPLDFVFYRGLNVHEASVLVTRASDHNPLLVEFSPGKPDK
What are the official names of this protein?
UPF0294 protein Ent638_0743.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SULA_YERPE
Sequence: MRTQSLKPYHANYHSLTTNDSPTRVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: UVRB_SHISS
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAL4_PONAB
Sequence: MEKLYNENEGMASNQGKMENEEQPQDERKPEVACTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGKAKEGKSEREGESEMEGGSEREGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Transcription elongation factor A protein-like 4, TCEA-like protein 4, Transcription elongation factor S-II protein-like 4.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family. TFA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALDC_BACSU
Sequence: MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSEIPKYGDFGIGTFNKLDGELIGFDGEFYRLRSDGTATPVQNGDRSPFCSFTFFTPDMTHKIDAKMTREDFEKEINSMLPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKTQPIFNFDNVRGTIVGFLTPAYANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTISQKMNMNLRLPNTADFFNANLDNPDFAKDIETTEGSPE
What is the function of this protein?
Converts acetolactate into acetoin, which can be excreted by the cells.  This may be a mechanism for controlling the internal pH of cells in the stationary stage.
What are the official names of this protein?
Alpha-acetolactate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the alpha-acetolactate decarboxylase family.
Protein: RL14_BORRA
Sequence: MVQMQTYLTVADNTGGKIAQCIKVLGGSKRRYAKVGDIIVIAVKQAIPNSPVKKGDVHKAVIIRTSKEIRRKNGTYVRFDDNACVILDANLNPRGKRVFGPVARELRDANFMKVVSLASEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NRDR_STAAS
Sequence: MKCPKCNSTQSKVVDSRHADELNAIRRRRECENCGTRFTTFEHIEVSQLIVVKKDGTREQFSREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTEVSSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILSENKRSDA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL21_FRATW
Sequence: MYAIIKNGGKQYKVKEDEVVKLEKFDLGIGEKVEFDTVLMGQTAAGEVKIGAPTVAGAKVVGEVVEQGRHKKVKIMKFRRRKHSMKQQGHRQYFTAVKVSSISL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RS12_DINSH
Sequence: MPTIQQLIRKPRQPKVKRSKSQHLESCPQKRGVCTRVYTTTPKKPNSAMRKVAKVRLTNGFEVISYIPGESHNLQEHSVVLIRGGRVKDLPGVRYHILRGVLDTQGVKDRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.