PharMolix/UniProtQA huggingface dataset:
Protein: MTA1_MOUSE
Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSSLIALADKHATLSVCYRAGPGADTGEEGEVEEEVENPEMVDLPEKLKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEEDGRDQSKLETKVWEAHNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQISASSVKATVVNGTGTPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNMSPHGIPARSSGSPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYMPINSAAIKAECTARLPEASQSPLVLKQVVRKPLEAVLRYLETHPRPPKPDPVKSSSSVLSSLTPAKSAPVINNGSPTILGKRSYEQHNGVDGNMKKRLLMPSRGLANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPLRPPPPAPVNDEPIVIED
What is the function of this protein?
Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator (PubMed:20682799, PubMed:20071335).  Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (By similarity).  In the NuRD complex, regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA (PubMed:17671180).  In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A (PubMed:20071335, PubMed:21965678).  Acts as a transcriptional coactivator of BCAS3, PAX5 and SUMO2, independent of the NuRD complex (PubMed:17671180, PubMed:21965678).  Stimulates the expression of WNT1 by inhibiting the expression of its transcriptional corepressor SIX3 (PubMed:20682799).  Regulates p53-dependent and -independent DNA repair processes following genotoxic stress (PubMed:20071335, PubMed:19805145).  Regulates the stability and function of p53/TP53 by inhibiting its ubiquitination by COP1 and MDM2 thereby regulating the p53-dependent DNA repair (PubMed:19837670, PubMed:19805145).  Plays a role in the regulation of the circadian clock and is essential for the generation and maintenance of circadian rhythms under constant light and for normal entrainment of behavior to light-dark (LD) cycles (PubMed:24089055).  Positively regulates the CLOCK-BMAL1 heterodimer mediated transcriptional activation of its own transcription and the transcription of CRY1 (PubMed:24089055).  Regulates deacetylation of BMAL1 by regulating SIRT1 expression, resulting in derepressing CRY1-mediated transcription repression (PubMed:24089055).  With Tfcp2l1, promotes establishment and maintenance of pluripotency in embryonic stem cells (ESCs) and inhibits endoderm differentiation (PubMed:28982712).
What are the official names of this protein?
Metastasis-associated protein MTA1.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with microtubules. Primarily localized in the cytoplasm in embryonic tissues. Localization at the nuclear envelope is TPR-dependent.
Protein: PP6R2_HUMAN
Sequence: MFWKFDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVSLITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDRLGGDESLLSLLYDFLDHEPPLNPLLASFFSKTIGNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAGLRQDVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEALEPDPLLTALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVGTEGLVDSFSQGLERSYAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCIAAILSHAAREERTEASGSESRVEPPHENGNRSLETPQPAASLPDNTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISEVIRGLPADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQAFSDYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADEDSPSAALFEACCSDRIQPFDDDEDEDIWEDSDTRCAARVMARPRFGAPHASESCSKNGPERGGQDGKASLEAHRDAPGAGAPPAPGKKEAPPVEGDSEGAMWTAVFDEPANSTPTAPGVVRDVGSSVWAAGTSAPEEKGWAKFTDFQPFCCSESGPRCSSPVDTECSHAEGSRSQGPEKASQASYFAVSPASPCAWNVCVTRKAPLLASDSSSSGGSHSEDGDQKAASAMDAVSRGPGREAPPLPTVARTEEAVGRVGCADSRLLSPACPAPKEVTAAPAVAVPPEATVAITTALSKAGPAIPTPAVSSALAVAVPLGPIMAVTAAPAMVATLGTVTKDGKTDAPPEGAALNGPV
What is the function of this protein?
Regulatory subunit of protein phosphatase 6 (PP6).  May function as a scaffolding PP6 subunit.  Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
What are the official names of this protein?
Serine/threonine-protein phosphatase 6 regulatory subunit 2, SAPS domain family member 2.
What is the protein family that this protein belongs to?
Belongs to the SAPS family.
Protein: KUP_METAC
Sequence: MFSKSDFRGIINSMGLVFGDIGTSPIYTLTVIFLLTRPTEVHVIGVLSLIIWTLITLVTVEYAWLAMSLGKKGEGGTIVLKELLVPLIKSGRNAAFITLLAYIGVSFLVGDGVITPAISILSAVEGLRIIPDFQDIGQGAIMFIAGIIAVALFSVQSKGTEEITWVFGPVMVLWFASLAFSGIASIFYTPGVLRAINPYYAISFLLHNGFTGFFVLSEVILCATGGEALYADMGHLGREPILKAWRLVFSALVLNYLGQGAFIIRNPESKNILFEMINQQAEVIYIPFLILSITATIIASQAMISGMFSIVYQGITTRIIPMLKIDYTSGKLRSQIYIGAVNWLLLISVLFMIFEFRDSHRLAAAYGLAVTGTMSITGLMMTLIFYLKGRMFRSFVSLFVTVIDVVFLLSNTYKIPHGGYWSIVIAAIAFSLIIIYTSGQKKLYELMNPMKIGDFLEKYKQVYASENKISGTALFFARDINYVPRYISNVMFENNIIYEDNIFISIIKCESPFGVKSSFAKDLAKGLRVFEINVGYMEVIDVVQILKDKGIQEKTIFYGIEDILTSNLIWKVFSVIKKLSPSFVQFYKLPSDKLHGVLTRFEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YOW4_SCHPO
Sequence: MSQIQDLKDENVEMDIDPQEQNEKKPLLLDELTKFTILHPYNYDSHIKLIEELKRLDKKKELSEARKTFQSIFPLSEDLWVDYLLDECKNCRTLDDYVRIKTLFDLAVQDYLSIKIWCMYLEFTLNLMDTSSFEQEQSELNGVITLTDAHSLFERAYQTCKFHFSKSQCVWTLYLEFLQTFGDALFEGEEEQEIVFKNKIYDFHIDRLKLPHEQIEETFTSLSTFVTNNWSPSEYEDVMVKSNKVYETTLKRNAKIFNKELLLNSANHSLEAYMDLINDESRRSTAELQYITTLYERAIVLYPLIPELWLQYTAWLSKVDFSSSQASSVAERATRNCSWIGRIWSIKLTYMTLSGASTSAVCEEKDRCLNSNLLVNFDEVIDFFSGFLKACLYLSSNEDKPQEFLKHQIHKVEDYLRKNHKGSKDARMRIELSKIYLYSEISDFESVEKCWSDMFHDFQNQALYWISRYISTMKYNPELAAETLKKSLYKNVDQPQLLFQFYQSIMDLNNDCFTNTSHLYDVLNAQRISFKRQLDSFAEETKQTVENTEPLKVPQADDTAALSKKRKPGQEGDVFKKSKPIEQHRNREELTVLVTNLPSDISENELKIFFKDCGNIIRIFILEDNQKDVKVAQIEFSETSEVLAAKTRDLKSIRGHEISVQIHVDTNLYVTNFPPTYDELDITKLFSAYGNVVDVRFPSLRYNTNRRFCYVQMRKPDEAHNALQLHKKLLEEKYPIQVFISDPLRRTPRSGAVYEGRELYVTNIDFKVNEKDVETFFRDYGQVESVRIPKRFNQHKGFGYVVMTTNQDAENALSAAGKQLGNRVLNVVLSKPRESLEKTRVSSNDNRTLAKSFETTESNKMSTPKKSFEQIKSKSLGVTNVDGTVNEARLRSLFESYGKLYRVVLHPEHEGAVVEFLDIHDAGKASLALEGHEIGGRLLHITTVNEMMHNVPSSMNHSDYNTSATRPRRLGSRTFQGFNSNHSNINSKKDDLDDKEMQIDAPKSNDDFRKMFLK
What are the official names of this protein?
Uncharacterized RNA-binding protein C1861.04c.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGS_ECODH
Sequence: MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQARELELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.
Protein: HIUH_RHILO
Sequence: MAETSKADGGRLTTHVLDTATGKPAAGLSIALYRLDGSARTHLKTVATNADGRCDAALLAGAEFRAGEYELVFAAGDYLRGQGTKLPEPAFLDSVPIRFGMAEAVHYHVPLLISPYGYSTYRGS
What is the function of this protein?
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
What are the official names of this protein?
5-hydroxyisourate hydrolase, HIU hydrolase, HIUHase.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
Protein: P2Y10_MOUSE
Sequence: MGSNSTSSAESNCNATYLPFQYSLYATTYIFIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHILSLPLRIYYYINRHWPFQRALCLLCFYLKYLNMYASIFFLTCISLQRCLFLLKPFRARNWKRRYDVGISAVIWIVVGTACLPFPILRNAGLANSTDSCFADLGYKQMDAVVLVTMVVIAELAGFVIPVITIACCTWKTTVSLKHPPIAFQGISERKKALRMVFMCAAVFVICFTPYHINFIFYTMVKESIITSCPTVKSTLYFHPFSLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSRESGSSMVN
What is the function of this protein?
Putative receptor for purines coupled to G-proteins.
What are the official names of this protein?
Putative P2Y purinoceptor 10, P2Y10.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYNS_PSEF5
Sequence: MLQSQFAQAPRLALADTIIDAKARKNLSWQDLTDGTGLSLAFVTAALLGQHALPATAADLVCDKLGLDQDASRLLQSIPLRGSIAGGIPTDPTVYRFYEMLQVYGSTLKALVHEQFGDGIISAINFKLDIKKVEDPEGGSRAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: EVA1_RHISA
Sequence: MTFKACIAIITALCAMQVICEDDEDYGDLGGCPFLVAENKTGYPTIVACKQDCNGTTETAPNGTRCFSIGDEGLRRMTANLPYDCPLGQCSNGDCIPKETYEVCYRRNWRDKKN
What is the function of this protein?
Salivary chemokine-binding protein which shows chemokine neutralizing activity and binds to host chemokines CCL3, CCL4 and CCL18 (PubMed:17640866, PubMed:18678732, PubMed:25266725, PubMed:20041127).  Binds to CCL3 with 1:1 stoichiometry (PubMed:20041127).
What are the official names of this protein?
Evasin-1, EVA1.
What is the protein family that this protein belongs to?
Belongs to the evasin C8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAJ_SYNP6
Sequence: MDGLKRYLSSAPILATIWFAITAGILIEFNRFFPDLLFHPL
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DEGS1_HUMAN
Sequence: MGSRVSREDFEWVYTDQPHADRRREILAKYPEIKSLMKPDPNLIWIIIMMVLTQLGAFYIVKDLDWKWVIFGAYAFGSCINHSMTLAIHEIAHNAAFGNCKAMWNRWFGMFANLPIGIPYSISFKRYHMDHHRYLGADGVDVDIPTDFEGWFFCTAFRKFIWVILQPLFYAFRPLFINPKPITYLEVINTVAQVTFDILIYYFLGIKSLVYMLAASLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNIPGKSLPLVRKIAAEYYDNLPHYNSWIKVLYDFVMDDTISPYSRMKRHQKGEMVLE
What is the function of this protein?
Has sphingolipid-delta-4-desaturase activity.  Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (PubMed:11937514, PubMed:30620337, PubMed:30620338).  Catalyzes the equilibrium isomerization of retinols (By similarity).
What are the official names of this protein?
Sphingolipid delta(4)-desaturase DES1, Cell migration-inducing gene 15 protein, Degenerative spermatocyte homolog 1, Dihydroceramide desaturase-1, Membrane lipid desaturase, Retinol isomerase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
What are the subcellular locations of this protein?
Mitochondrion membrane. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS19_RICBR
Sequence: MARSVWKGPFVDGYLIKKVQKLMESGKSEMIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNEEMVGRKLGEFSPTRTFHGHGADKKVKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PTN5_RAT
Sequence: MEEKVEDDFLDLDAVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLVSPREESAHEYLLSASRVLRAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVRLTSPDPEDPLSSYINANYIRGYNGEEKVYIATQGPIVSTVVDFWRMVWQERTPIIVMITNIEEMNEKCTEYWPEEQVVHDGVEITVQKVIHTEDYRLRLISLRRGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQQLRREGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLYEKQLSLQSSE
What is the function of this protein?
May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 5, Neural-specific protein-tyrosine phosphatase, Striatum-enriched protein-tyrosine phosphatase, STEP.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUAB_BOVIN
Sequence: MAKTVLRQYWDIPEGTECHRKTYATTSIGGAAGLVVSAYSVALKTPTSFLEGVARTGRYTFTAAAIGAIFGLTSCISAQVREKPDDPLNYLIGGCAGGLILGARTRSYGIGAAACAYMGLTAALVKMGQLEGWQVFAEPKV
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11, Complex I-B14.7, CI-B14.7, NADH-ubiquinone oxidoreductase subunit B14.7.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA11 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: ARLY_JANSC
Sequence: MTDTGSSDTNTDTTGTSKANTMWGGRFAAGPDAIMEAINASISFDQRMARQDIEGSRAHAAMLAATGIVESSDVDVIREGLLTVLSEIEGGTFQYSTALEDIHMNVEARLTEIIGTPAGRLHTARSRNDQVATDFKLWVRDQMDAAISGIEALQRALLGQAEAGADWVMPGFTHLQTAQPVTWGHHMMAYVEMLGRDASRFRDARTRMNESPLGAAALAGTSFPIDRDMTAEALGFDRPSANSLDAVADRDFALEFLSAASICAMHLSRFAEELVIWSSAQFRFVALSDRFSTGSSIMPQKKNPDAAELIRAKIGRIFGANVALMTVMKGLPLTYSKDMQEDKEQTFDAADNLMLALAAMEGMVRDMQANVPSLEAAASSGFSTATDLADWLVRELNMPFREAHHVTGSLVKLAEDKGCDLPDLALSDMHSVHGDITDGVFDVLGVHNSVASRTSYGGTSPVQVREQVARWRDILG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGTP_ECO55
Sequence: MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: THIG_VIBCH
Sequence: MLKIADKTFQSRLFTGTGKFSNRHVMAEALAASGSELVTMALKRIDLAQRDDDILAPLLSMQMNLLPNTSGAKNAADAVYAAELAREALATNWLKLEIHPDPKYLMPDPIETLLAAEQLVKQGFIVLPYCHADPVLCKRLEEVGCAAVMPLGSPIGSNQGLASKTFLEIIIDQAKVPVIVDAGIGSPSDAAQAMELGADAVLVNTAIAAAHDPIAMAKAFKLAVEAGRMAYESGLPSRVKMATASSPLTGFLDFVS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_SALTI
Sequence: MVTIRLARHGAKKRPFYQVVVTDSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVKKAA
What is the function of this protein?
In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity.
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: DAPE_PSEPK
Sequence: MTAPAELSPTLQLACDLIRRPSVTPVDADCQAQMMNRLGAVGFQLEPMRIEDVDNFWATHGSQDGPVLCFAGHTDVVPTGPVQQWQHEPFEALIDADGMLCGRGAADMKGSLASMVIASERFVQDYPNHRGKVAFLITSDEEGPAHHGTKAVVERLKARNERLDWCIVGEPSSTTLLGDVVKNGRRGSLGAKLTIRGKQGHVAYPHLARNPIHLAAPALAELAAEHWDEGNAFFPPTSFQISNLNSGTGATNVVPGELTALFNFRFSTESTVEGLQARVSAILDKHELDWSVDWALSGLPFLTEPGELLDAVAASIKGVTGRDTQPSTSGGTSDGRFIATMGTQVVELGPVNATIHQVDERILASDLDLLTEIYYQTLVRLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: SYG_PYRFU
Sequence: MKFDKYEYLQDLMRRRGFAWGSFEIYGGARGFYDYGPLGATIKRKIEKKIREAFIREGFFEIETPDITPEQVFIASGHVEKFVDPLVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKIIREHNIRCPECGGELSDVWYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKDEVLRLYPIEHQLKDLGMIELTAEEAVKKGYVMNTFFAYYMVMIKRILLDIGIPEDKIRFRQQLPEERAHYSADTWDAEIYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVKKLNVTLNMKKVGPKLKEKVKEINEKLKSMSQEELRKLVEELNANGKVIIEGHELEKEDLIIKEVEEKIQGEKIVPHVLEPSFGIDRPFYLLLENSLTVDEDGRVYLKIKKDMAPIEVAVLPLVAKEPLTTIAYEIYRNLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTVDNQTPEDGTVTIRDRDTREQIRVKIEEVPRKLKELIFG
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCS1_MAIZE
Sequence: MSSSSLSPTAGRTSGSDGDSAADTHRREKRRLSNRESARRSRLRKQQHLDELVQEVARLQADNARVAARARDIASQYTRVEQENTVLRARAAELGDRLRSVNEVLRLVEEFSGVAMDIQEEMPADDPLLRPWQLPYPAAAMPMGAPHMLHY
What is the function of this protein?
May contribute to developmentally specific patterns of gene expression.  Binds specifically to ocs elements which are transcriptional enhancer found in the promoters of several plant genes.  OCSBF-1 is able to bind to a site within each half of the ocs element as well as to animal AP-1 and CREB sites.
What are the official names of this protein?
Ocs element-binding factor 1, OCSBF-1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADD_METI4
Sequence: MIKKTTSFRLAIFGGSFDPIHYGHLICAMDCLEQISLNKIIFMPCSRSPFKKQNPVASALQRLEMIQLAIKPFKNFEVSSFEVQSPAPSYSIRTVQEFHKLYPHAELFWIIGSDQVPGLPRWKDYAELIQIVKFIVVSRSNYYPYEKRDYLVPLPKIRYVDISSTEIRERVKKELPIFHLLPQAVFQYIKENSIYIPNRTVHEK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RL27_ACIBT
Sequence: MATKKAGGSTKNGRDSNPKMLGVKVYGGQTVTAGNIIVRQRGTEFHAGANVGMGRDHTLFATADGVVKFEVKGQFGRRYVKVETV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ACOT1_RAT
Sequence: MEATLSLEPAGRSCWDEPLSITVRGLVPEQPVTLRAALRDEKGALFRARALYRADAHGELDLARAPALGGSFTGLEPMGLIWAMEPERPFWRLVKRDVQTPFVVELEVLDGHEPDGGRLLARAVHERHFMAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTICYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPLVEQKSFIPVERSDTTFLFLVGQDDHNWKSEFYANEISKRLQAHGKEKPQIICYPEAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHSVAQLDAWQQLQTFFHKQLGGKSHGVSPKI
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.  More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20).
What are the official names of this protein?
Acyl-coenzyme A thioesterase 1, Acyl-CoA thioesterase 1, CTE-I, Inducible cytosolic acyl-coenzyme A thioester hydrolase, LACH2, ACH2, Long chain acyl-CoA thioester hydrolase, Long chain acyl-CoA hydrolase, Palmitoyl-coenzyme A thioesterase.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RRF_XANC5
Sequence: MLTQIKQDAQTRMTKSIDALRHSLTTIRTGRASPALLDGIKVKAYGADTPLNQVASISVSEGRSLVISLFDKGMIKDVEKAIYASDLGLTPTVVGTVIRLNLPPLTEERRKELSKSVHGEGEDSKVAIRNIRRDANQQVKDLLKDKAVTEDEARSAEDDIQKLTDKAIKDVDEVVKGKEQELMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_YERE8
Sequence: MALTKAEMSEHLFEKLGLSKRDAKDLVELFFEEVRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVESATPKE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ALKB3_RAT
Sequence: MGDKRQRARVQGAWATPTKSQSAARPATPARSRPSQTPGPSWRSKEQQQCDRRFVFKEPQLVVRAAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDLKEADWILERLCQDVPWKQRMGIREDITYPQPRLTAWYGELPYTYSRVTMEPNPHWLPVLWTLKSRIEENTGHTFNSLLCNFYRDEKDSVDWHSDDEPSLGSCPVIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSRERRVNLTFRTVYPDPRGAPGDTSAELPLR
What is the function of this protein?
Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A).  Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation.  Has a strong preference for single-stranded DNA.  Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3.  Can repair exocyclic 3,N4-ethenocytosine adducs in single-stranded DNA.  Also acts on RNA.  Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons.  Requires molecular oxygen, alpha-ketoglutarate and iron.
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, Alkylated DNA repair protein alkB homolog 3.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with ASCC2 and ASCC3 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage. Predominantly localizes to the nucleus.