PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_LEGPH
Sequence: MLFARRLEQLKDLNRIRNFSIIAHIDHGKSTLADRFIQICGGLTEREMSSQVLDSMDIERERGITIKAQCVSLNYTAKDGKTYLLNFIDTPGHVDFSYEVSRSLAACEGAILVVDAAQGVEAQTLAVCYTAIDQSLTVLPVLNKIDLPQAEPERVISEIEDIIGLDAQDAIRVSAKSGLGVNDVLEALVANIPPPKGDVHAPLQALIIDSWFDSYLGVVSLVRIVNGAIRKGDKMRVMSTGRAYEVDQVGIFTPKRTKLDALYAGEVGYVVAGIKEIQGAPVGDTLTLDRNPADKVLPGFQRVKPQVYAGLFPVSSDDFEAFREALAKLSLNDASLFYEPESSEALGFGFRCGFLGMLHMEIIQERLEREYNLDLISTAPTVVYQIVTQKGETLLIDNPSHLPPTPQIKEMYEPIVRANILVPQDYLGPIITLCVERRGVQVSMTYSGRHVSVVYDIPMSEVVSDFFDRLKSVSRGYASLDYNFQRFQIADLVKMDILINSERVDALAVIVHRDSAHSRGKLIAEKMQQLIPRQMFDVAIQAAIGSHIIARQTVKALRKNVTAKCYGGDVTRKRKLLEKQKAGKKRMKQVGHVEIPQEAFMAVFQTDKKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYC21_MAGFU
Sequence: ADAPTAFNQCKACHSIEAGKNGVGPSLSGAYGRKVGLAPNYKYSAAHLASGMTIDEAMLTNYLANPKATIPGNKMGASFGGLKKPEDVKAVIEYLKTVK
What is the function of this protein?
Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway.  However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
What are the official names of this protein?
Cytochrome c2 iso-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
Protein: YIDD_ALBFT
Sequence: MIRDVLVGIVKGYRLLLSPWLGSSCRFEPTCSAYSLQALQTHGAAAGSYLTLTRLARCHPWCAGGSDPVPSEKPRFKSQLFTQLIHPSSEKKSS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SLYX_ECO57
Sequence: MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: RS15_SULSY
Sequence: MSITAEKKQELIKKFALHENDTGSPEVQIAVLTERIRNLTEHIKANKKDLHSRRGLIGMVNKRRKLLNYLKRESEERYRKIIEALNIRETSNESK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RF3_ECOL6
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity).
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT29_HUMAN
Sequence: MMLKGITRLISRIHKLDPGRFLHMGTQARQSIAAHLDNQVPVESPRAISRTNENDPAKHGDQHEGQHYNISPQDLETVFPHGLPPRFVMQVKTFSEACLMVRKPALELLHYLKNTSFAYPAIRYLLYGEKGTGKTLSLCHVIHFCAKQDWLILHIPDAHLWVKNCRDLLQSSYNKQRFDQPLEASTWLKNFKTTNERFLNQIKVQEKYVWNKRESTEKGSPLGEVVEQGITRVRNATDAVGIVLKELKRQSSLGMFHLLVAVDGINALWGRTTLKREDKSPIAPEELALVHNLRKMMKNDWHGGAIVSALSQTGSLFKPRKAYLPQELLGKEGFDALDPFIPILVSNYNPKEFESCIQYYLENNWLQHEKAPTEEGKKELLFLSNANPSLLERHCAYL
What is the function of this protein?
Involved in mediating interferon-gamma-induced cell death.
What are the official names of this protein?
28S ribosomal protein S29, mitochondrial, MRP-S29, S29mt, Death-associated protein 3, DAP-3, Ionizing radiation resistance conferring protein, Mitochondrial small ribosomal subunit protein mS29.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y1149_STRP3
Sequence: MGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSDNDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTIEASRQGAEIAETPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTELYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLDSYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAFAVMVRYE
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein SpyM3_1149.
Protein: RLME_XANCB
Sequence: MPSRSKSSQRWLKEHFADPFVKKAQAEGMRSRAAYKLEELLQRDRLLKPGMVVVDLGAAPGGWSQQVRKSMGASGRVVALDILEMPPLAGVEFLHGDFREQAVLSEFEAMLGDVPVDLVLSDMAPNKSGMDAVDQPRMMHLAELAMEFADTHLKVGGAFLIKLFQGVGSDDYIRELRRRYEKVTIRKPAASRKRSAEVYVLGQGKRAQIK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM11_CANTT
Sequence: MSTFLQSFKISQASDEYKQRRKTQMLKFFTASAITILTSRFAYRSTIARQYVPTLFQGNHSPPLSYNFTTDAAVAVATGTILCGSVSSMLVLGGFWILDVSNLGEFGWRMKEKLGGLEKEKHLGEMEMDEESRYIQDSLNDLLDGKYDFEEEGGNNSVA
What are the official names of this protein?
Altered inheritance of mitochondria protein 11.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HLDD_PSYIN
Sequence: MFIVTGGAGFIGSSIVKSLNERGITDILVVDDLTDGAKFVNLVDLQIMDYMDKDEFITQIVSGQDFGDIEAIFHEGACSATTEWNGKFMMENNYEYSKDLLHYCIERDIPFLYASSAATYGGNDTFKEELKYEKPLNVYGYSKFQFDQYVRRIWEDAAAHDETLPQIVGFRYFNVYGPREQHKGSMASVAFHLNNQLNAGENAKLFEGEHKRDFVYIGDVCKVNLWFFDNNVSGIYNLGTGQAESFLEVGQAVVAYHQKGEVERIPFPEHLKGRYQSFTEADLTNLRAAGYKDTFKSVAQGTAEYMAWLNR
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: ATP62_METCA
Sequence: MEQIDFFARVLGHLGPVTVSDSLLTSVLVAGLLSAASAVLTRRRTALPDRVQVVLEGIVSACENAVRDVIPTAYREVTPFIMSLWLFLATANLISLVPGFDSPTRDLSVTSALAVLVFFSVHWFGIRQQGLSAYLKHYLTPNPVLLPFHLIGEITRTLALAIRLFGNMMSMELIGLLLLIIGGLFVPVPVLLLHVVEGLVQAYIFGILALVYIAGGIQSGPQQENHSP
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 2, ATP synthase F0 sector subunit a 2, F-ATPase subunit 6 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBL_CYRRA
Sequence: VGFKAGVKDYKLTYYTPEYETKHTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTNLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMLTSIVGNVFGFKALRSLRLEDLRIPVAYAKTFQGPPHGIQVEGDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDYIEKDRSPGIYFSQDWVSLAGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HFQ_ALKCK
Sequence: MKATVNIQDQFLNQLRKESIPVTVFLLNGFQLRGQVKGFDNFTVIVETEGRQQLVYKHAISTFAPQKNVQLKNEAEV
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: SYGB_STRPD
Sequence: MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDIQTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTDAIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVHTLTVLLNDEALELDFLDIHSGCVSRGHRFLGTETTITSADSYEADLRSQCVIVDAKERQEMIVEQIKTLEVEQGVQVDIDENLLNEVLNLVEFPTAFMGSFEAKYLDIPEEVLVTSMKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQKLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIYKFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVATAIREHYLPDAAGGALPETKVGAVLALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYDLSFDSLTYTNKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAVAEALVKASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQQLEQVFALSPVINDFFDNTMVMAEDQALKNNRLAILSDLVSKAKTIAAFNQLNTK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_LIMRJ
Sequence: MRVVLQKVNHAAVSIDDEVVGKIGLGYFLLVGFAPDDTEEKLNYLVHKITNLRVFEDENGKMNKGLRDVNGAILSVSQFTLYADTKHGNRPGFSQAASPEIAEPLYDLFNQKLAATGIPVETGHFGAMMKIDLENDGPTTIIYER
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJP_ECOLI
Sequence: MRYSKLTMLIPCALLLSACTTVTPAYKDNGTRSGPCVEGGPDNVAQQFYDYRILHRSNDITALRPYLSDKLATLLSDASRDNNHRELLTNDPFSSRTTLPDSAHVASASTIPNRDARNIPLRVDLKQGDQGWQDEVLMIQEGQCWVIDDVRYLGGSVHATAGTLRQSIENR
What are the official names of this protein?
Uncharacterized lipoprotein YbjP.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DAPD_CORGL
Sequence: MTTASATGIATLTSTGDVLDVWYPEIGSTDQSALTPLEGVDEDRNVTRKIVTTTIDTDAAPTDTYDAWLRLHLLSHRVFRPHTINLDGIFGLLNNVVWTNFGPCAVDGFALTRARLSRRGQVTVYSVDKFPRMVDYVVPSGVRIGDADRVRLGAYLADGTTVMHEGFVNFNAGTLGASMVEGRISAGVTVDDGTDVGGGASIMGTLSGGGQHVISLGKRCLLGANSGCGIPLGDDCIIEAGLYITAGTKVLFDGSLHKASTLAGSNGLIFRRDSVSGQVVAVPNTKVVELNTALHSN
What is the function of this protein?
Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_ECO24
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: YL032_MIMIV
Sequence: MPHKAPKSKLFRTRYVEDSDDETRGRSRNRSVEKSRSKSLTRSKSKSPKKSRSKSLDRSKNVKTTKSKNTNKSNKYTEEDSEDSEDSESDQDDDKSDNEQSDSELDDSESDDDETDDNESDNDKSKDNFENIIESKENDFRNIIFENINEKFAIGKFGDFEVIINRDNGYINATQLCKDCGKDYKNWNQNEKSREFVKKLSQYTGLSNTNLLTKIIGGNNVKLRGTYVHPIILTNIGNWISPTFAIKIGEWIEEWKKFSRKNTLKYYKELSKIELYSNNDKEKQIQLALQKSLGGKIEVRTKHGYVDLLTKDKIIEIKSYDNWKHALGQILAYGELYENKNKCIYLFDIPSKNEIANIKIILKKFGISLLCI
What are the official names of this protein?
Putative KilA-N domain-containing protein L32.
Protein: F16PA_ECOK1
Sequence: MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_STAA8
Sequence: MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: XIP2_ORYSJ
Sequence: MGLVHALLPFAAAAALLLLAAPPPATADDPGLAVYWGRHKEEGSLREACDTGRYTTVIITFYNAFGHGRYSLDISGHPLAAVGADIKHCQSRGITVLLSIGGQGGAYSLPTNASAADVADNLWNAYLGGHRAGVARPFGDDAAVDGIDFFIDQGGADHYDDLARRLDGYNKYYRGRVGVLLTATTRCSYPDHRLEKALATGVFARIHVRMFGDEQCTMSPRYSWEKWAAAFPGSKVYIGLVASPEQDSAWMFQKDLYYEMLQFVRSLPNYGGLAIYDRYFDKKANYTGEG
What is the function of this protein?
Fungal xylanase inhibitor.  Possesses competitive inhibiting activity against several fungal endo-1,4-beta-D-xylanases belonging to glycoside hydrolase family 10 (GH10) and family 11 (GH11).  May function in plant defense against secreted fungal pathogen xylanases.  Is similar to class III chitinases, but does not exhibit chitinase activity.
What are the official names of this protein?
Xylanase inhibitor protein 2, Class III chitinase homolog h.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Xylanase inhibitor subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HMGN2_CHICK
Sequence: MPKRKAEGDTKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAAPKKSEKVPKGKKGKADAGKEGNNPAENGDAKTDQAQKAEGAGDAK
What is the function of this protein?
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer.  May be involved in the process which maintains transcribable genes in a unique chromatin conformation.
What are the official names of this protein?
Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the HMGN family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPP_AQUAE
Sequence: MIVELSHPLIKHKVNTARIQDTSAEKLRKTLKELGFMLVYEALKDILLEEKEVRTWIGNKRFNYLNEEEIVFVPILRAGLSFLEGALQVVPNAKVGFLGIKRNEETLESHIYYSRLPELKGKIVVILDPMLATGGTLEVALREILKHSPLKVKSVHAIAAPEGLKRIEEKFKEVEIFVGNVDERLNDKGYIIPGLGDIGDRLYAVSVY
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: FOLT_LEUMM
Sequence: MENTTRTWVFPKLDTRQFVLLAMLMALHMVLSRLTVGTNVLQVSFAFVTMSLIAKWYGPLWSMLIAAILDVIGATIINPGAFFVGFTFTAMISALIYSLAYFKHDKTSWWRVSVAVGLVLLIANIGLNSIWLVMMYHTAHDWPSFLAFITPRVIKNLIMFPIQVGISYFLLNNQVISHTTKKIFS
What is the function of this protein?
Folate-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (By similarity).  Upon coexpression with EcfA1A2T in E. coli allows 5-formyltetrahydrofolate uptake; uptake requires both FolT and EcfA1A2T.
What are the official names of this protein?
Folate transporter FolT, Folate ECF transporter S component FolT.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYR_CAMJR
Sequence: MKSIIFNEIKKILECDFALENPKDKNLAHFATPLAFSLAKELKKSPMLIASDLASKFQNHDCFESVEAVNGYLNFRISKTFLNELANQALTNPNDFTKGEKKQESFLLEYVSANPTGPLHIGHARGAVFGDTLTRLARHLGYKFNTEYYVNDAGNQIYLLGLSILLSVKESILHENVEYPEQYYKGEYIADLAKEAFEKFGKEFFSQENIPSLADWAKDKMLVLIKQNLEQAKIKIDSYVSERSYYDALNATLESLKEHKGIYEQEGKIWLASSQKGDEKDRVIIREDGRGTYLAADIVYHKDKMSRGYGKCINIWGADHHGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGEPYKMSKRAGNFILMSDVVNEIGSDALRYIFLSKKCDTHLEFDISDLQKEDSSNPVYYINYAHARIHQVFAKAGKKIDDVMKADLQSLNQDGVNLLFEALNLKAVLNDAFEARALQKIPDYLKNLAANFHKFYNENKVVGSANENDLLKLFSLVALSIKTAFSLMGIEAKNKMEH
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_MYCGE
Sequence: MRLRKVKNALLKINQSPYFYSKDKFAKFTKKQLVLELGCGKGTFLIKEAQKNNNFLFIGIEREPTIVLKAINKINKLDFNLENILLLCTDAKQLDDYFQAESVQKIFINFPDPWPKKRHIQRRLTSPDFLKLFWNLLVKNGLIEFKTDNDKLFEYTLTTLQENSQIFEIIHQITDLNNSEFSFQNSITEYEQRFMELEIPIKKLVIKKII
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: KHSE_PSEAB
Sequence: MSVFTPLERSTLEAFLAPYDLGRLRDFRGIAEGSENSNFFVSLEHGEFVLTLVERGPVQDLPFFIELLDVLHEDGLPVPYALRTRDGEALRRLEGKPALLQPRLAGRHERQPNAHHCQEVGDLLGHLHAATRGRILERPSDRGLPWMLEQGANLAPRLPEQARALLAPALAEIAALDAERPALPRANLHADLFRDNVLFDGPHLAGLIDFYNACSGWMLYDLAITLNDWCSNADGSLDPARARALLAAYANRRPFTALEAEHWPSMLRVACVRFWLSRLIAAEAFAGQDVLIHDPAEFEMRLAQRQNVEIHLPFAL
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: OCRL_MOUSE
Sequence: MEPRLPIGAQPLAMVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKDSSSWYQKLDTMDKPAYSGLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPPSSSTRMLSREKEASNKEQPKVTNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWLDCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGMMLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKNELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFFFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSYLEKEKSLLQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGNNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNINTNMIATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLGNEED
What is the function of this protein?
Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2.  Able also to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate.  Regulates traffic in the endosomal pathway by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with endosomes.  Involved in primary cilia assembly.  Acts as a regulator of phagocytosis, hydrolyzing PtdIns(4,5)P2 to promote phagosome closure, through attenuation of PI3K signaling.
What are the official names of this protein?
Inositol polyphosphate 5-phosphatase OCRL, Inositol polyphosphate 5-phosphatase OCRL-1, Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, phagosome membrane. Early endosome membrane. Membrane, clathrin-coated pit. Cell projection, cilium, photoreceptor outer segment. Cell projection, cilium. Cytoplasmic vesicle. Endosome. Golgi apparatus, trans-Golgi network. Note=Also found on macropinosomes.