PharMolix/UniProtQA huggingface dataset:
Protein: SYNG1_BOVIN
Sequence: MAGVVEQKSGLVRDKLGEASKRNGLINTRSLVAESRDGLVSVYPAPQYQSCRVVGSVASAGPDGARNEPLQQLLDPSTLQQSVESRYRPNLILYSESVLRPWGDGVAADCCETTFIEDRSPTKESLEYPDGKFIDLSPEDIKIHTLSYDVEEEEEFQELESDYSSDTESEDNFLVMPPRDHLGLSVFSMLCCFWPLGIAAFYLSHETNKAVAKGDFHQASTSSRRALFLAVLSITIGTGIYVGVAVALIAYLSKSNHL
What is the function of this protein?
May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.
What are the official names of this protein?
Synapse differentiation-inducing gene protein 1, SynDIG1, Dispanin subfamily C member 2, DSPC2, Transmembrane protein 90B.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Early endosome membrane; Single-pass type II membrane protein. Postsynaptic density membrane. Synapse. Cell projection, dendrite. Cell projection, dendritic spine. Note=Shuttles between the cell surface and early endosome membrane.
Protein: Y018_CLOB1
Sequence: MKNKKALFIPLFIIILFIAFFNKIINFIINIKWFKEVNYLAVYFTKMRAIIILMIPIFIIFFISIWMYYKSLIINKNKSVVDIGLNKNNYGKKLFFIFNFIVSIFLAYIFSSSYWYRILQFNNSVDFNVKDPIFFKDVSFYIFKLPLFESLYKVIISLLLFLVITTFIAYFILEAKYKIQSKKDINLKNINHGIKSFAGKQLAIVSGLIILFISFGHLIKIWNLVYSSNGVSFGASYTDVHATLLFYKIIVVITLISSIVTLLSIVKGKFKPVSICIGITIFLIVSQNIASFLVQNFIVKSNEKTLEQPYIKNNIDLTRKAFALDDIEIRDFDIKNDLQKQDITDNKASIDNIRINSFKPTLEFYNQVQIIRYYYTFNDIDIDRYNINGKYNQVFLAAREIDTDALNPNTWQNRHLIYTHGFGAVMNKVNSVTSEGQPDFVIKDIPPYNKTNIKLANPRIYFGEKTNDYVIVNTKINEFDYPKEDSNKTNKYNGHAGIKMSFINRLLFAINKKDINFLLSKDIKKDSKIIINRNIVERAKKIAPFLTYDSDPYMVIYNGKIYWIIDAYTTTNRYPYSEPYDSINYIRNSAKVVIDSVDGDINFYITDKKDPIVNNYAKIFKGLFKEEKDAPKEIREHFRYPKDLFSIQSKVLGKYHVKDPGVFYNGEDLWEVSKDQKHVEGETNTNDAPYIIMKLPDQNKEEMVLLNYFNVMKKDNMIALFGARMDGEQYGKKILYKLPSDKTVYSPYLFKQKINQDTNISKELSLWNREGSKVQYGDTIILPIKNSLLYIEPLYLRASGKNSIPEMKRVILSYNDKLVLSSSIQEGIKEIFNSKDNKINDKNEKDSTKTIDDSKLKKAQEYYNKAIEAQKNGDWTKYGENINELGNILNSIK
What are the official names of this protein?
UPF0182 protein CLB_0018.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FIBA_ODOHE
Sequence: SDPAGGEFLAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: CCL2_HUMLU
Sequence: MDNYRRLHTPVALCVASPPAPPTTSWKSMEGLVQCSANHVPLSPITFLERSSKAYRDNTSLVYGSVRYTWAQTHHRCLKLASALTTHLGISPGDVVATFSYNLPEIYELHFAVPMAGGILCTLNARNDSAMVSTLLAHSEAKLIFVEPQLLETARAALDLLAQKDIKPPTLVLLTDSESFTSSSYDHYNHLLANGSDDFEIRRPKNEWDPISINYTSGTTARPKAVVYSHRGAYLNSIATVLLHGMGTTSVYLWSVPMFHCNGWCFPWGAAAQGATNICIRKVSPKAIFDNIHLHKVTHFGAAPTVLNMIVNSPEGNLHTPLPHKVEVMTGGSPPPPKVIARMEEMGFQVNHIYGLTETCGPAANCVCKPEWDALQPEERYALKARQGLNHLAMEEMDVRDPVTMESVRADGATIGEVMFRGNTVMSGYFKDLKATEEAFEGGWFRSGDLGVKHEDGYIQLKDRKKDVVISGGENISTVEVETVLYSHEAVLEAAVVARPDKLWGETPCAFVTLKEGFDNDVSADQIIKFCRDRLPHYMAPKTVVFEELPKTSTGKIQKYILKEKAMAMGSLS
What is the function of this protein?
Involved in the biosynthesis of prenylated phenolics natural products which contribute to the bitter taste of beer and display broad biological activities (Probable).  Catalyzes the ligation of CoA on isovalerate to produce 3-methylbutanoyl-CoA (PubMed:23300257).  Can also use butanoate, hexanoate, pentanoate, 3-methylpentanoate and 4-methylpentanoate as substrates with a lower efficiency (PubMed:23300257).
What are the official names of this protein?
Isovalerate--CoA ligase CCL2, HlCCL2, 3-methylpentanoate--CoA ligase AAE2, 4-methylpentanoate--CoA ligase AAE2, Butanoate--CoA ligase CCL3, Hexanoate--CoA ligase CCL3, Pentanoate--CoA ligase CCL3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GVPK_DOLFA
Sequence: MVCTPAENFNNSLTIASKPKNEAGLAPLLLTVLELVRQLMEAQVIRRMEEDLLSEPDLERAADSLQKLEEQILHLCEMFEVDPADLNINLGEIGTLLPSSGSYYPGQPSSRPSVLELLDRLLNTGIVVDGEIDLGIAQIDLIHAKLRLVLTSKPI
What is the function of this protein?
May play a structural or regulatory role in gas vesicle synthesis.
What are the official names of this protein?
Protein GvpK.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: Y2117_YERPY
Sequence: MSQPPFWQQKTLAEMSDSEWESLCDGCGQCCLNKLIDEDTDEIYFTNVACDQLNIKTCQCSNYERRFELEEDCIKLTRENLVTFAWLPPTCAYRLIGEGHDLPRWHPLLTGSKAAMHGERISVRHIAVRESEVVDWQDHILNKPSWAK
What are the official names of this protein?
UPF0260 protein YPK_2117.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: WETA_BEAB2
Sequence: MALWTSSYPVDTGDRDPSFAWPDTDVPSAGLDESQHDLFAQFLDFEAGHGSTSSATVAVAEPFYMDPSHHHHHPHHHAHGESSTTSSGVSNADEFDFLSSSSNPGAAGYDVDPSTLAMFAQDPAAMYSTTSGVTVSDTELERLEGISLHSPKKGDGTFADRAASPTPVAAPAIAVNATTNAANTTTNARRSKKIVDALSSTFRKATTMRKTRKVSQTLQRAVSPSMENPPMAIKPGSAQSAAPVPRGRRAHRAHTQHALQHQQQQHQHQQQQAHQISESPPILQINTGLANSGGFVAGQFEDPFGGEISPTHAPQPQSQPPQMRYYSQGGLGTPLDSPTRSAAMLQQQWQQQQQQQHNGAQQHQWSAASSQQELWWGGAAGGGAIEAKNIDANMAMHSQHGELPYDVHADAGRVAPNGLLIHMPQPRPGSSSVHDLSLNAHTYLPPPPPVPTENTRSARPPRAPSSGARHHHRTTSSSPMRKQRGTSVSPSPGGNGSGGGTRQSRHSSGGSAASSSQRSASGRVSVPGTPSSSGIKKRRSRDAGSGSFSADEAGGFTLVGGGGGGGGGGGGGGIGFVNFTPNDGGVLMTGVAPSGSSKTKARREKEAQERRRRLSEAAMKAVAAAGGDIRKLREQGFEL
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).  Acts as a crucial regulator of both conidiation capacity and conidial quality (PubMed:26243054).  Plays a role in virulence (PubMed:26243054).
What are the official names of this protein?
Developmental regulatory protein wetA.
What is the protein family that this protein belongs to?
Belongs to the wetA family.
Protein: SYM_YERE8
Sequence: MAQVAKKILVTCALPYANGSIHLGHMLEHIQADIWVRFQRMRGNQVHFICADDAHGTPIMLKAQQLGIEPEQMIAEMSQEHQQDFAGFAISYDNYHSTHSDENRELSSLIYSRLKANGYIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIDPKSAVSGATPVMRESEHFFFDLPAFSDMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPDAPGKYFYVWLDAPIGYMGAFKNLCDKRGDLDFDEFWRKDSEADLYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKAGTYLKHLDADCLRYYYAAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFAGKLADHLADPALYKTFTDAATSIADAYSNRESSKAIREIMALADIANRYVDEQAPWVVAKEEGRDADLQAICSMGINLFRVLMTYLKPVLPALTERTEAFLNTELTWDSIEQPLLGHQINAFKALFNRIDVDKVNEMVASSKEDMAAAVAVTGPLADDPIQETISFDDFAKVDMRIALIQQADFVEGSDKLLKLKLDLGGETRQVFSGIRSAYPDPKVLEGRLTVMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDNGAQPGMQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTFA_ECO7I
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVALAERFLQQKRLVPLQGFELNSLRSCRIALLFCLPVLELGLEWLDGFHEILIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFISLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGLD_EMENI
Sequence: MRVPSLSVLSFLLGTALAAASNFEAGLLSSGKVSLGDWKSAHEKASQFVAKLNTTEKIKLITGSSVTTTNGETFTALDILDGDMGAQAYYYVSAFSLSSALAMTWDKEAMYEQGRAIAAEFYGKGIQMVAGPTSQPLGRTPWGGRLVESFGPDPYLNGIATGLETRAYADVGVIAGAKHFILNEQETNRTGGMGGGGGAPGGGGMGRGAEFSSSVPGGMSPTSSAGAIPSSTSTPGGSGMGGGMAGSSAFSSSSSSGAPYSSNADDKTLHETYLWSFYDAVHSGLGGVMCAMTKVNGTLSCQSSSLLLDILKTELGFPGMVWPDTNGQQDALASAANGLDYGSSSLWSESTIEGYLESNNITEARLNDMAIRNLMGYYYVNLDNGTQPSTAAQDDYVDVRANHAKLIRSHGSKSMVLLKNKNNTLPLYKPHKMAIFGSHARAAVAGPNMQFSVEGSGPTYDGHIATDSGSGQASLPYLITPENALNIKASQDGTMLRWIANDTYSSSTGSALVMQGSSSTSVTPSVSAYSENMDVCLVFINALAGEGADRTELRNTDQDNLINEVADNCDNTVVVINTVGARILDSWIEHENVTAVLYGSLLGQESGNSIVDVLYGDVNPSGRLTYTIAKTESDYNVDICYTAQCNFTEGNYIDYRYFDAYNVTPRYEFGYGLSYTDFAYSNLHIQGPSALSTYPTGQLAVGGYEDLWDTVAKVTVTIRNAGSLDGAEVPQLYISYPDVAKQPVRQLRGFHNVYIKKGQSTKVTFELRRRDISYWDVQHQKWAVAPGTYEAWVGASSRDLRTHGSFVVKTKA
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase D, Beta-D-glucoside glucohydrolase D, Cellobiase D, Gentiobiase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: QOX4_STAA3
Sequence: MSTIMKHTVGFIASIVLTLLAVYVTLYTSLTFHAKLTIIFGFAFVQAGLQLLMFMHLTEGKDGRLQTFKVIFALVITLCFVVGTYWVMQGGHSSHL
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
What are the official names of this protein?
Probable quinol oxidase subunit 4, Quinol oxidase polypeptide IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RHCG_TETNG
Sequence: MGCVQSFRNFCDRPKNTNVRISLPAVCFVWQIAMIILFGVFIRYNEEADTHWVEYRKKENISSDIENDFYFRYPSFQDVHVMIFVGFGFLMTFLKRYSFGAVGFNFLIAAFGLQWALLMQGWFHSLDYTDGKIKIGIENLINADFCVAGCLIAYGAVLGKVSPVQLMVLTLFGITLFAVEEYIILNLIHARDAGGSMVIHTFGGYYGLSISWMLYRPNLEQSSNLQGSVYQSDVFAMIGTLFLWMFWPSFNSAITDHGDGQHRAAINTYLALASTVLTTVAISSLFQKHGKLDMVHIQNSTLAGGVAVGTAAEFMLMPYGSLIVGFCCGIISTLGYIYLTPFMEKYLKIQDTCGIHNLHAMPGLIGGIVGAITAAAATESVYGKEGLVNTFDFVGPFKNMVPTTQGGHQAAGLCVAICFGIGGGIMVGCILRLPIWCDPADDNCFNDEPYWELPEEEEIIPPILHYNNHMVNKDV
What is the function of this protein?
Functions as an ammonia transporter.  May play a role in the elimination of ammonia in the gill (By similarity).
What are the official names of this protein?
Ammonium transporter Rh type C, Rhesus blood group family type C glycoprotein, Rh family type C glycoprotein, Rh type C glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: RECA_SHEPA
Sequence: MKIDPNKEKALNAVLGQIEKQFGKGSIMKLGEDRSMDVETISTGSLALDVALGAGGLPMGRIVEIYGPESSGKTTLTLEVIAAAQKQGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKDREEVIGNETRVKVVKNKIAAPFKQAEFQILYGQGINSTGELVDLGVQHKLIEKAGAWYSYKGDKIGQGRANAGKYLIENPAISDEIETTLRAMLLGNGEKVSADSADTAGDNIDLETGEVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_STRS2
Sequence: MSVIERLTKAAHLIDMDDIIREGHPTLRQVAEEVAFPLSDQEIILGEKMMQFLKHSQDPVMAEKMKLRGGVGLAAPQIDVSKRIIAVLVPNPEDEEGNPPAQAYSLQEVLYNPKIVAHSVQEAAMEGGEGCLSVDREVQGYVVRHARVTVDYMDKNGEKHRIKLKGFNAIVVQHEIDHLNGVMFYDRIDPEHPFAVKEGMLVIE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: HSLV_DESRM
Sequence: MFHATTIVAVKRGTKVAVAGDGQVTFGQNTIMKHTARKVRRLHNGQVLAGFAGSVADAFTLFEKFEGKLEEYHGNLMRAAVELAKAWRTDKYLRTLEAMLIVANQEHLLVLSGNGEVIEPDEGVTAIGSGGPYALAAARALTKHTNLSPKDITYEALNLAADICVYTNKNIVVEEI
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CR1CA_BACTE
Sequence: MEENNQNQCIPYNCLSNPEEVLLDGERISTGNSSIDISLSLVQFLVSNFVPGGGFLVGLIDFVWGIVGPSQWDAFLVQIEQLINERIAEFARNAAIANLEGLGNNFNIYVEAFKEWEEDPNNPETRTRVIDRFRILDGLLERDIPSFRISGFEVPLLSVYAQAANLHLAILRDSVIFGERWGLTTINVNENYNRLIRHIDEYADHCANTYNRGLNNLPKSTYQDWITYNRLRRDLTLTVLDIAAFFPNYDNRRYPIQPVGQLTREVYTDPLINFNPQLQSVAQLPTFNVMESSRIRNPHLFDILNNLTIFTDWFSVGRNFYWGGHRVISSLIGGGNITSPIYGREANQEPPRSFTFNGPVFRTLSNPTLRLLQQPWPAPPFNLRGVEGVEFSTPTNSFTYRGRGTVDSLTELPPEDNSVPPREGYSHRLCHATFVQRSGTPFLTTGVVFSWTDRSATLTNTIDPERINQIPLVKGFRVWGGTSVITGPGFTGGDILRRNTFGDFVSLQVNINSPITQRYRLRFRYASSRDARVIVLTGAASTGVGGQVSVNMPLQKTMEIGENLTSRTFRYTDFSNPFSFRANPDIIGISEQPLFGAGSISSGELYIDKIEIILADATFEAESDLERAQKAVNALFTSSNQIGLKTDVTDYHIDQVSNLVDCLSDEFCLDEKRELSEKVKHAKRLSDERNLLQDPNFRGINRQPDRGWRGSTDITIQGGDDVFKENYVTLPGTVDECYPTYLYQKIDESKLKAYTRYELRGYIEDSQDLEIYLIRYNAKHEIVNVPGTGSLWPLSAQSPIGKCGEPNRCAPHLEWNPDLDCSCRDGEKCAHHSHHFTLDIDVGCTDLNEDLGVWVIFKIKTQDGHARLGNLEFLEEKPLLGEALARVKRAEKKWRDKREKLQLETNIVYKEAKESVDALFVNSQYDRLQVDTNIAMIHAADKRVHRIREAYLPELSVIPGVNAAIFEELEGRIFTAYSLYDARNVIKNGDFNNGLLCWNVKGHVDVEEQNNHRSVLVIPEWEAEVSQEVRVCPGRGYILRVTAYKEGYGEGCVTIHEIEDNTDELKFSNCVEEEVYPNNTVTCNNYTGTQEEYEGTYTSRNQGYDEAYGNNPSVPADYASVYEEKSYTDGRRENPCESNRGYGDYTPLPAGYVTKDLEYFPETDKVWIEIGETEGTFIVDSVELLLMEE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae including Spodoptera species.
What are the official names of this protein?
Pesticidal crystal protein Cry1Ca, 134 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIC(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: MUTS_RICPR
Sequence: MTLCNMNLHEFRQKYNYNVATKMMQQYLDIKFAHLDCLLLFRMGDFYELFYEDAILASNILGIALTKRGKNCEEEIPMCGVPYHALEHYLTKLIEENYKVAICDQLETPEEAKKRDGYKAVVTRDVTRIITPGTIIEENLISVTEPNYLTSLVIPKNKKTASICCVDLSTSKIFVINVPETEILNELARLKSREILLSENLKSSNISDSILKQFNCRITYQVDSFFAINKCEKIILDFYKIRDIKGIGEISNSQICAIGSILEYLSLTQKQNIPHLPIPKIINFHNYMTIDFSTRRNLEIVTNLQGNLYGSVLNTLNHTVTTQGGRLLYHFLSSPLTNIAKINHRLNITEFFYSNLGIVTRIRELLKNTSDIERCLTRITMNRSSGRDLLSIKYTLETAKTIKGLFSESYGLNLPHFIEKIIKPLSGDAELYNLIHMSIREDAPNNLNDGGIIKYEFHPKIAQLNDLINNKKLHVEKLKDQYRKETRIESLKISHNNVLGFFIDITPKNVNKILDPKFIHRQTTINSVRYTTYELQNLENELVNAQTLVIRLEKELYTDICRKVIEKSSYLKILANSLSGLDVFCNFAYIADEYDYTKPEFTNDLSFDIVKGRHPVVEAALRKTSKSFVYNDCHLSEAERIWLITGPNMAGKSTYLRQNAIITIIAQIGSFVPAKSAKIGVVDKIFSRIGAADDLIKGQSTFMAEMLETSAILAQSTKNSLIILDEVGRGTSTYDGVSIAWSVLEYIHDKLQCRCLFATHYHELTVMKNFLPALQNYTIAIEESGKDILFLHNIILGASNKSYGLHVAALAGLPTSVINRAAQILLKFEKISISKEKNILSNASNNLSLFNFEHEKPISNSKLDEEFKTIDPDKISPKEALELIYKFKKLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: SYM_FRATW
Sequence: MRKILVTNALPYANGDLHLGHMLGYIQSDIWVRFQKLQGNQCIFVCGSDTHGTPIMLKAKSLGITPEELVTKYSNRHLQDFTDFEINFDNYHSTHNSLNKEIVEDIYNKLNNKNLISKKAIAQAYDPEAKMFLPDRFVKGTCPKCKAEDQYGDSCEVCGATYDPTELINPRSVISGQSPIQKNSEHFFFDLPALEKNIKDWIESNTLLQPEVANKLAEWFEQGLQSWDISRDAPYFGFAIPGTNEQKFFYVWLDAPMGYIASFKDYCNKNNINFGDFWGDSSSESELYHFIGKDIIYFHTLFWPAILSSTGYKTPTSVFANGFLTVNGKKMSKSRGTFIQARTYLDNLEPSYLRYYFASRLTSRIDDIDLNLEEFVTKSNSDIVGKVVNIASRCAGFIYKKFDATLSGEIFDPELESEFSKNHDAITQAFEKREFAHAVRLIMALADKANQFIDYHKPWQLAKEEGQEQKVHQVCSQGINMFKVLIVYLKPIIPSIVAEAERFLNIQFISWADAPKFLINHKIDKFKPLATRIEKEKVDKILEDTKKMLENEQAPQSKKEEPKLDIAAECTFDDFMKVDLRIAKITEASHVEGADKLLKLILDLGGVTKQVFAGIKSAYKPEDLIGKHTIMVANLAPRKMKFGMSEGMVLAAGDGKGIYILEPHEGAQPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO1A2_PARHA
Sequence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
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-2(I) chain, Alpha-2 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: LEU3_BORPA
Sequence: MTHQIAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHAVLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEIVSGLDILIIRELTGDIYFGTPRGVRTAADGAFAGEREGYDTMRYAESEVRRIARIGFESARKRNKKLCSVDKANVLETSQFWRDLVIEVSRDYPDVELSHMYVDNAAMQLVRNPRQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSASLNAAGQGLYEPSHGSAPDIAGQGIANPLATILSAAMLLRYSLNLAPQADRVEAAVRKVLADGLRTADIHEAGTTKVSTSQMGDAVLKALG
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_CLOAB
Sequence: MSKVIFHVDVNSAFLSWTAVEKLKNGEDIDIRKVPSVIGGDEKSRHGVVLAKSTPAKKYGIVTGESLYHARKKCPNILVFPPRFDTYRKASESMMNLLKRFTPHIEKYSIDECFMDVTNDLRGMESVEFASIIKERIKNELGFTVNVGISTNRLLAKMASELNKPDKINTLYKHEIKDKMWPLPVGELFMVGKSMKRKLNELHIKTIGELAKYDVNILKAKFKSHGNMVWEYANGIDNSDISRYRDEIKCISNETTLSMDLTDTEKIHKILVTLCENLGQRLRDANKYCTSISVNIRTSDFRNYSHQKKLKNAVSSTRDIILYADKIFNEMWGREPIRLLGVQLSGLCSGSSVQISMFDEKTDTRNEILDKTLDSIRKKYGDNVIMRSVLLEKEEK
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_CUPNH
Sequence: MLPVQTSNLAAAFTDAVRALAPADATLPAVTFERPKVAAHGDLACNVAMQVARALKSNPRELAQRIVDAVQADTRAQGLVQAMEIAGPGFINLRLTPAAKADVLRAVLAEGDHYGARERGVHGQVLVEFVSANPTGPLHVGHGRQAALGDALANLLSWQGWHVHREFYYNDAGVQIQTLALSVQARARGLKPGDASWPEAAYNGDYIADIAADFLAGKTVSASDGEPVTASGNVEDIDSIRKFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYSDGRVEAAVQSLVGKGKTYESEGALWLRTTDDGDDKDRVMKKSDGTYTYFVPDVAYHTTKWERGFTKVINVQGSDHHGTIARVRAGLQGLDMGIPQGYPDYVLHKMVTVMKNGEEVKISKRAGSYVTVRDLIEWSNGGDETIRGCLDTGVADWPQHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIFESWGGADWEARLAELAGADLSAVTGPEASAQAQALGRRLAEFPDMLSGAAAELAPHAVAFYLRDLAGDFHAFYNADRVLVDDEAVKRARLALLAATRQVLRNGLAVIGVSAPRRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S2546_XENTR
Sequence: MQPRRPDRFDGLEYRGTSWGRGDGDVPPYQHGFPARSFSSSGDLSQHWVTTPPDIPGSRNLHWGEKSPQYGADSNAGPAAVGEESSSSSSGGEHLNRFAGFGIGLASLFTENVLAHPCIVLRRQCQVNYHARNYQLSPFSIVNIMYSFTKTQGFRALWKGMGSTFIVQGISLGAEGMLSEFTHLPRELNHKWNPKQIGGHLLLKGLVYVIVTPFYSASLIETVQSEIIHDNPGILDCLKEGIGRVLNLGVPYSKRLLPLLVLTFPTVLHGILHYIISSTIQKCVLFFIKKKSPAQLPGDGSNAVQNKLEDYFPELIANFAASLCADVLLYPLETVLHRLHIQGTRTIIDNTDLGHEVVPINSQYEGLKDCINTIKREEGGLGFYKGFGAVVVQYTLHAIVLQITKIIYSSVVQTAS
What is the function of this protein?
May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
What are the official names of this protein?
Solute carrier family 25 member 46.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.