PharMolix/UniProtQA huggingface dataset:
Protein: GDA1_ASPFU
Sequence: MAQTQRSRYLKTGAIVAALLLMLLWISPSRPMHPSFPQGQPSTSAPAKGKCSKPHDPKKPLIQYALMIDAGSQGSRIHVYRFNNCGPSPELEDEVFFQTEPKKGGSGLSSYKEDAEGAAKSLDPLMEVAMKNVPDEYKSCSPIAVKATAGLRMLGPELSQKILDAVRNRLETVYPFPVVSKEKGGVEIMDGSDEGVYAWITTNYLLGKIGGPDETPTAAVFDLGGGSTQIVFQPTFPKSKSGGMPERLSEGDHKYDLQFGGRHFELYQHSHLGYGLMAARKAIHTSIIENMLASSPKDLSWLKQPIPNPCIGPEMEKNVTLEFPEGHKLAPEVQVTMVGPKVGSTAAQCRGLAEKTLNKEAACTLAPCSFNGVHQPSLEKTFAREDVYIFSYFYDRTKPLGMPDSFTLDELHQLTSTVCGGEDSWGIFAGIEGALKELRDRPEWCLDLNFMMSLLHTGYEMPLSREVKIAKKIKNRELGWCLGASLPLLSQESGWTCRIKEVS
What is the function of this protein?
After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol.
What are the official names of this protein?
Probable guanosine-diphosphatase, GDPase.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RPA12_RAT
Sequence: MELARPCSNFQSDLDFCPDCGSVLPLPGVQDTVICPRCGFSIDVRDFGGKVVKTSVVFNKLGTVIPMSVDEGPESQGPVVDRRCSRCGHEGMAYYTRQMRSADEGQTVFYTCINCKFQEKEDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit H, Zinc ribbon domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HEM1_STAA3
Sequence: MHFIAISINHRTADVALREQVAFRDDALRIAHEDLYETKSILENVILSTCNRTEVYAVVDQIHTGRYYIQRFLARAFGFEVDDIKAMSEVKVGDEAVEHLLRVTSGLDSIVLGETQILGQIRDAFFLAQSTGTTGTIFNHLFKQAITFAKRAHNETDIADNAVSVSYAAVELAKKVFGKLKSKQAIIIGAGEMSELSLLNLLGSGITDITVVNRTIENAMKLAAKHQVKYDELSSLPNLLESADIVISSTSAQSYIITNEMIERIAENRKQDSLVLIDIAVPRDIEPGISAITNIFNYDVDDLKGLVDANLRERQLAAATISEQIPAEIHAHNEWISMLGVVPVIRALREKAMAIQAETMDSIDRKLPGLSERERKIISKHTKSIINQMLKDPIKQAKELSSDKKSNEKLELFQNIFDIEAECPHEQAKQQKESKVKEISARRIFSFE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CLPX_MYCTA
Sequence: MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGEKGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGLIPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRLFEMDGVELEFTDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRSERRDKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: Y3881_SHESA
Sequence: MTLGQQAESLAQGYLEQQGLTFVARNVRYPFGEIDLVMRHKHHWVFVEVKYRSANQFGGAIQALSKAQIGRIRMAASHYLQTHKLDVPCRFDVVAIEDAQIHWLVDAF
What are the official names of this protein?
UPF0102 protein Shewana3_3881.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RS21_ENT38
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: FAR6_PENMO
Sequence: DGRTPALRLRF
What are the official names of this protein?
FMRFamide-like neuropeptide FLP6, DGRTPALRLRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CXB2_BOVIN
Sequence: MDWGGLHTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYYRHEKKRKFIRGEIKTEFKDIEEIKKQKVRIEGSLWWTYTGSIFFRVIFEAAFMYVFYVMYDGFAMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRFCSGKSKKPV
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction beta-2 protein, Connexin-26, Cx26.
What is the protein family that this protein belongs to?
Belongs to the connexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: DHQSD_ARATH
Sequence: MAASSTNARLTNPPRLLSKPRLSPTSVANLRFPAADFSTRFFADSSSPRLRSVPFPVVFSDQRRRRSMEPSNVYVASNSTEMEIGSHDIVKNPSLICAPVMADSIDKMVIETSKAHELGADLVEIRLDWLKDFNPLEDLKTIIKKSPLPTLFTYRPKWEGGQYEGDENERRDVLRLAMELGADYIDVELQVASEFIKSIDGKKPGKFKVIVSSHNYQNTPSVEDLDGLVARIQQTGADIVKIATTAVDIADVARMFHITSKAQVPTIGLVMGERGLMSRILCSKFGGYLTFGTLDSSKVSAPGQPTIKDLLDLYNFRRIGPDTKVYGIIGKPVSHSKSPIVHNQAFKSVDFNGVYVHLLVDNLVSFLQAYSSSDFAGFSCTIPHKEAALQCCDEVDPLAKSIGAVNTILRRKSDGKLLGYNTDCIGSISAIEDGLRSSGDPSSVPSSSSPLASKTVVVIGAGGAGKALAYGAKEKGAKVVIANRTYERALELAEAIGGKALSLTDLDNYHPEDGMVLANTTSMGMQPNVEETPISKDALKHYALVFDAVYTPRITRLLREAEESGAITVSGSEMFVRQAYEQFEIFTGLPAPKELYWQIMSKY
What is the function of this protein?
Bifunctional dehydroquinate dehydratase-shikimate dehydrogenase enzyme that catalyzes two steps in the chorismate biosynthesis pathway.
What are the official names of this protein?
Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic, DHQ-SDH protein, DHQase-SORase, Protein EMBRYO DEFECTIVE 3004.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ODPA_MOUSE
Sequence: MRKMLAAVSRVLAGSAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SEC13_ASPOR
Sequence: MHDAGLDYYGRRLATCSSDKTIKIFEIEGETHRLVETLKGHEGAVWCIAWAHPKFGTILASSSYDGKVLIWREQHQNTTSPVAVNTWTKVFDFSLHTASVNMVSWAPHESGCLLACASSDGHVSVLEFQDNSWTHQIFHAHGMGVNSISWAPAASPGSLISANPGPGQQRRFVTGGSDNLLKIWDYNSETKSYNLSQTLEGHSDWVRDVAWSPSILSKSYIASASQDKTVRIWTSDVSNPGQWASQQLEFDTVLWRVSWSPSGNILAVSGGDNKVSLWKENLKGQWEKVKDIEE
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein sec13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: PYRD_CORST
Sequence: MTLYDRALKLMFLLPPERIHGIISGALQTLHLATPVNRVMEKAVRVHDPVLRQTVFGVDFPAPLGLAAGFDKNAEAIDSWGAIGFGYAEMGTVTPKSQPGNPTPRLFRLPEDKAILNRMGFNNKGALVVADNLRARRSRDVVGINIGKNKTSEDAVADYRATSTLLGQLADYLVVNVSSPNTPGLRDLQAVEELRPILEVVKKSTTTPVLVKIAPDLSDEDIDAVADLAVELELAGIVATNTTISRSGLKTPASKVEKMGAGGISGAPLENRSLEVLKRLHERVGDKLVLVSVGGISTPEQAWERITAGASLLQGYTPFIYGGLGWIRGIHRGIAAQIKAHGLDSIEQAVGSGLEWKAL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EFG_CHLCV
Sequence: MSDQEFDLSKIRNIGIMAHIDAGKTTTTERILYYAGRTHKIGEVHEGGATMDWMEQEQERGITITSAATTVFWLDCKINIIDTPGHVDFTIEVERSLRVLDGAVAVFDAVSGVEPQSETVWRQANKYGVPRIAFVNKMDRMGANYFAAVESMKEKLGANAIPVHCPIGAESQFVGMVDLISQKALYFLDETLGAKWEEREIPEDLKEKCAELRYALLEELATVDEGNEAFMMKVLEDPDSITEEEIHQVMRKGVIENKINPVLCGTAFKNKGVQQLLNVIVKWLPSPKDRGIIHGINLKNNEEVHLEPRKDGPLAALAFKIMTDPYVGRITFIRIYSGTLKKGSAILNSTKDKKERISRLLEMHANERTDRDEFTVGDIGACVGLKYSVTGDTLCDDNQEIVLERIEIPEPVIDMAIEPKSKGDREKLAQALNALSEEDPTFRVTSNEETGQTIISGMGELHLDILRDRMIREFKVEANVGKPQVSYKETITKNGSSETKYVKQSGGRGQYAHVCLEIEPNEPGKGNEVVSKIVGGVIPREYIPAVMKGVEEGLNTGVLAGYGLVDVKVSIVFGSYHEVDSSEMAFKICGSMAVKEACRKAAPVILEPIMKVAVTTPEDHLGDVIGDLNRRRGKILGQESSRSMAQVNAEVPLSEMFGYTTSLRSLTSGRATSTMEPAFFAKVPQKIQEEIVKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRC11_ARATH
Sequence: MERIRDLSSKKAAVIFTKSSCCMCHSIKTLFYELGASPAIHELDKDPEGREMERALRALGSSNPAVPAVFVGGRYIGSAKDIISFHVDGSLKQMLKDAKAIWL
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Glutaredoxin-C11, AtGrxC11, Protein ROXY 4.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT6_NEUCR
Sequence: MSNSMRDLIDGEAELDDEEDDESFDEEAGDRPRRRPNIDDSSEEEEDDEDEEEARKIREGFIVDEDEEDEAEDSDARERRRRKKRRREREEEEQLDEEDLDLIGEAIPEWERKPQPQRLKRGHRDDHRPTERRGLAEIFSDEDEEHDDRGYGRPSGRAQADEFDDFIEDDYPEDDEERRHREEDEEVARPKDRGLNIDTTGLDKDALEDMDAIFGNGEDYEWALQLEEEQEHAERTKEDIELQDVFEPSQLKEKLLTDEDNRIRFNDEPERFQLDRKAFKNLQMTSDQFKEEARWISNLMLPSKNLSSELHGPFNKAVGKVLEFFVIDGVEVPYVFQHRRDYLIHAKKMRNPNRRDDPDAPEYTVDAEKLLTQDDLWKVLDLDIRFRSFLEKRNALEQTYDKLKEKTRDDILEEMIRQAQSIEELQDLQDYLNFQYSAELKDLAANDNSAQREIKRAGGRTAQFERIRRSNAYKFVQALGITPDRLAKNILRESSKVTSEDDSRLPDDLADTLVDADFPTGELVINAARQMLAEEMFASPRMRKHFRKNFYGMGIVSCRRTDKGLRKIDEANPYYEVKYLKNMSIADLAVRPELFLKMMKAEEEGLIEIKVSLENDREFRQQLFSDFASENFSELADKWNAERQKVIDLAFDKLVKVIVKGVKDSLRTACQDELLKTCRELYFKRLDQAPYKPKGMVIGTTPRVLTLSNGMGDPNREPVSWVSMDEDGRILEHGTFTNLARDESQREALAELVRRRQPDVIGISGFSADTHRLIKDVEGLVSEKGLVGPEYDDPETNEYRSDLLEVIVINDEVARLYKDSPRAVADHPSLNPMTRYCIALARYMQNPMKEYAALGKDVTSLQIHPYQQYLPQAKLLKHLETAMVDMVNLVGVDINVAMQDANTAHLLPYVAGLGPRKAQLLIKGINKNGGVVTSRDELVGDPERHKLPVLGPRVWNNCASFLFIEYEPTNPESDPLDNTRIHPEDYDLARKVAADALGLDEEDVKAETDENGAGAIVRKLFKDDEQDKVNELILEEYAEQLEREYQQRKRATLETIRAELQVPYEELRKKFESLTVDQVFTMLTGENRDSLCEGMIVAANVRVVKDDFAIVKLDCGIEGRIESHDVSYRHSIKDVLHVGQVVQAKLIDLNRKEFVSKLSMRDEEMRRPFRRHFDHGRDQWDYRKEDEDREELREKDKSTGRAQRVVNHPLFKPFNSTQAEEYLGSQPSGEVVIRPSSKGNDHLAVTWKVADGVFQHVDVLELQKENEFAVGRVLRVGKYTYQDLDELIVDHVKAMAKKVDELMQCDKFQKGSRNETEKWLTTYMDANPNRSTYAFCIDTKHPGYFFLCFKASRNSRVNAWPVRVIPHAFELMKSQYPDVRALCNGFKLRYQSEMLKQQSGGR
What is the function of this protein?
Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters.  Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).
What are the official names of this protein?
Transcription elongation factor spt-6, Chromatin elongation factor spt-6.
What is the protein family that this protein belongs to?
Belongs to the SPT6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HBA_SAGMY
Sequence: VLSPADKSNVKAAWGKVGGHAGDYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVALVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHHPADFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DNAK_HAEDU
Sequence: MGKIIGIDLGTTNSCVAVMDGDKPRVLENAEGARTTPSIIAYTDKETLVGQPAKRQAITNPKNTLFAIKRLIGRRFTDNEVQRDIEIMPFEIAKADNGDAWVNVKGDKLAPPQISAEVLKKMKKTAEDFLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDSKKENQIIAVYDLGGGTFDISIIEIDNFDGEQTFEVRATNGDTHLGGEDFDNRVINYLVEEFQKEQGVDLRNDPMAMQRVKEAAEKAKIELSSAQETEVNLPYITADATGPKHLNIKVTRAKLEALVEDLVSRSLEPLKTALADAGLSVSEINDVILVGGQTRMPLVQKKVADFFGKEPRKDVNPDEAVAIGAAVQGGVLAGDVTDVLLLDVTPLSLGIETMGGVMTSLIEKNTTIPTKKSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLEGINPAPRGMPQIEVTFDIDANGIINVSAKDKNTGKEQQIKIQASSGLSDEEVEQMVRDAEANAESDRQFEELVQTRNQADSIAHATRKQISEAGDALTAEDKAKIETALAELETAAKGEDKAEIEAKIEAVIKASEPLMQAAQAKAQTNQAGEQQSSAKDDSVVDAEFEEVKENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CTPD_MYCBO
Sequence: MTLTACEVTAAEAPFDRVSKTIPHPLSWGAALWSVVSVRWATVALLLFLAGLVAQLNGAPEAMWWTLYLACYLAGGWGSAWAGAQALRNKALDVDLLMIAAAVGAVAIGQIFDGALLIVIFATSGALDDIATRHTAESVKGLLDLAPDQAVVVQGDGSERVVAASELVVGDRVVVRPGDRIPADGAVLSGASDVDQRSITGESMPVAKARGDEVFAGTVNGSGVLHLVVTRDPSQTVVARIVELVADASATKAKTQLFIEKIEQRYSLGMVAATLALIVIPLMFGADLRPVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHGVLVKSAVVVERLADTSIVALDKTGTLTRGIPRLASVAPLDPNVVDARRLLQLAAAAEQSSEHPLGRAIVAEARRRGIAIPPAKDFRAVPGCGVHALVGNDFVEIASPQSYRGAPLAELAPLLSAGATAAIVLLDGVAIGVLGLTDQLRPDAVESVAAMAALTAAPPVLLTGDNGRAAWRVARNAGITDVRAALLPEQKVEVVRNLQAGGHQVLLVGDGVNDAPAMAAARAAVAMGAGADLTLQTADGVTIRDELHTIPTIIGLARQARRVVTVNLAIAATFIAVLVLWDLFGQLPLPLGVVGHEGSTVLVALNGMRLLTNRSWRAAASAAR
What is the function of this protein?
Involved in heavy metal homeostasis.  Probably exports nickel and cobalt ions out of the cell (By similarity).
What are the official names of this protein?
Probable cobalt/nickel-exporting P-type ATPase, Cation-transporting P-type ATPase CtpD.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_HELHP
Sequence: MQEKMEVQYMVVSFSHKNVDIATREKLSFSQEEIVPFLQEINVCDSIRESILLCTCNRVELYVSMIDKKRAREHIYECFCTHKNIALEDIKNIALMRLNQYAIYHIFSVASSLDSLVIGETQITGQLKLAYKLAFENALCAKDMTRLMHFAFKCAASVRKETDISAHSVSVASTAVRMAEQKLALCDKTLENLPVLVIGSGEMGRLACKHLQNANAQITLVSRTKENARKLALELDSSINIESWEHLEQLLGQYEVLFSATSAPNCIIQSKMVQVSQKQRWWFDLALPRDIENIQMENLHIFCVDDLEEIVQEHKNAREDSAKKAQKILERYSVEFFKWLQTLGIDPIIKHIRYLAKQSALKELDRAVKKGFLPASYQQNVEKILHGAFNTFLHQPTIRLKQASENPQGDPIIEAMKNVFDISDDVVMLNGYKCEKDTIF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: FSDH_FUSHE
Sequence: MALTVFEHASALWYRLQGSVSLAVLSTLAVVIAGWYILSSISLYFSRRQFIALHGCKPIANRYPSKWFGINFILEAGRTYKERRYLDALTWNFRNIGYTHEVRALGGTSVWTVEPENIKAVLTSKFKDYSLGNRPAVMGPLLGRGVFVTDGEEWSHSRALLRPNFAKDQVADLSMIERHLQQLLKMIPDDGKAIDLNDLILSFTMDSSTEFLFGESTETLTSGINRQFSDAFAYSLHDISSGLRLGPWYKFRRTDPKAVQSHRICREYADKYVEKALEYRRNYIKSVEDGATDKPSIDGGDSRRTFLRELALATDDREKLRDELLSLLLAGRDTTASLIGSLLFSLAKKPECWEKVRSEIEETLHGDLPSYEQLRNFKYAKYCVNEALRLYPPVPNNAKIAIRDTVLPRGGGPEGRDPIIVPKDAPVIYTVYALHRRYDLFGDDADDFRPERWENQRYTWEFLPFNGGPRICLGQQYALVETLYVLVRFAQHFSKIESMDPEPWTESLALTVSSGNGVKVKLERGSSDVHGLSTQGVLIDYGGLFAPTQKVPGTGVTQISKGKA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of fusaridione A, a bright yellow trans-fused decalin-containing tetramic acid with antimicrobial activity (PubMed:23614392).  The PKS module of fsdS catalyzes the formation of the polyketide unit which is then conjugated to L-tyrosine by the condensation domain of the fsdS NRPS module.  Activity of the Dieckmann cyclase domain (RED) results in release of the intermediate fusaridione A (PubMed:23614392).  The unstable pyrrolidinedione ring of fusaridione A is opened through a reverse-Dieckmann reaction to afford its ring-opened form (PubMed:23614392).
What are the official names of this protein?
Cytochrome P450 monooxygenase fsdH, Fusaridione A biosynthesis protein H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LRIQ4_MOUSE
Sequence: MHHSSSGSRCVLQNGLELTVILPRLHRFDIIDTFKTLTKELLRQEHLPKVLQKKEPHQLTDRTFFIDGSNQGLKTIPSEILALKELEEVHLENNQIAEIPQGIQQLQNTKVLYLHNNSLQDLCPELGALSSLESLDLSGNPLVISSLHVVSRLRTLRELRLYRTGLTEIPTGICKSLHHLELFGLSENFLESLPEEIVNQTKLREIYLKQNHFEVFPCDLCVLYNLEVIDLDENKLKSIPGDIGHLVRLQKFYVASNHLMSLPESLSQCSKLSVLDLTHNSIHSLPSSLELLTELTEVGLSGNRLEKVPRLLCSWVSLHLLYLRNTSLHGLRDSFKRLINLRFLDLSQNHIEHFPVQICALKNLEILALDDNKVRQLPPSISLLSNLKILGLTGNDLLSFPEEIFSLISLEKLYIGQDQGSKLSSLPENIKRLMNLKELYIENNRLEQLPASLGLMPNLEVLDCRHNLLKQLPDAICRTRNLRELLLEDNLLCCLPENLDHLVNLKVLTLMNNPMVDPPIYVCNQGNEAIWKHLKENRIRKMMATTIQAWWRGIMVRKGYGSYEELLKARKKGKSPPKDKKGKKAAKGKPEKGNKK
What are the official names of this protein?
Leucine-rich repeat and IQ domain-containing protein 4.
Protein: GAB3_MOUSE
Sequence: MSTGDTVCMGWLIKSPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSNKPIRVIDLSECTVWKHAGPGFIRKEFQKNFVFIVKTTSRTFYLVAKTEEEMQVWVHSISQVCNFSHLEDGADSMESLSHMPSSFQPSPASSLHTVHVANSALLKDDRNTNSVVTEETRRESEFLFLPDYLILSNCETGRLHHASLPTRCDSWSNSNHSLAQTSFDDVFLDGLQPFISNNLVHPLHHGKVSQDFPSIRPQASLIWNREINGPSRNLMSSSPLLESSLNPTVHVEEKQVSLPSGVKELNIMSNTPPPRPPKPSYLSEQRQDQPLLTGHSSNKKPGYTMVPRRISLSGLDHVGSWKGDVQSQSLRHRDKRLSLNLPCKFSPIYPTASPSAEDSYVPMSPKGTASELRPHCSQDDYIPMSSSMLPELPADLEPPPVNRNLKPQRKSRPPPLDSRNLSTIQEHTSLTRTYTVPCNRTSFLSPQRNGINCARLFSTPSEEEEEEEEEEEEEEEEEKYIQMEEYGTVSSLSRSALSWTKKFSLDYLALDFNSTSPAPVQKKLLLSEEQRVDYVQVDEQKTQALRSTKQEWTDERQSKV
What are the official names of this protein?
GRB2-associated-binding protein 3, GRB2-associated binder 3, Growth factor receptor bound protein 2-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the GAB family.
Protein: CYSN_SALG2
Sequence: MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGVKHLVVAINKMDLVDYCEETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: GLGA_STRP4
Sequence: MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYYDMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDFDDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVLTIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSYAHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAKNKAKLQERVGLPVRXXXPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPAFEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGTLPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNLQKQAMESDFSWDTACKSYLDLYHSLVN
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RUVA_CERS1
Sequence: MIGKVAGILDFRGPDHVLIDVRGVGYIVYVSDRTLASMPGLGEGVALYTELVVREDLLQLFGFPTMIEKEWHRLLMTVQGVGAKAGMAILGALGAEGTARAITLGDARSIQAAPGIGPKIAQRVVLELKSKAPALMAMGGGTAALAPSEPPEPEPGTSSGSRRKTRAPEPPRPSHTADALSALANLGYQPTDAAQAVAQAAGESPDADTAALIRAALKLLAPKS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.