PharMolix/UniProtQA huggingface dataset:
Protein: ARAG_ECOL5
Sequence: MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGAGKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAENIYLGQLPHKGGIVNRSLLNYEAGLQIKHLGMDIDPDTPLKYLSIGQWQMVEIAKALARNAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKDGRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPISLAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAITAGMMLCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPGAEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGVAVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PEPX_STRPC
Sequence: MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHNDHYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRASKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2594_BURCM
Sequence: MDARLLEILVCPICKGPLHYDRAAQELICNADKLAYPIRDGIPVMLVDEARQTVEGTPVDPAGPAGS
What are the official names of this protein?
UPF0434 protein Bamb_2594.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: MUTS_LIGS1
Sequence: MPQKTKQTPMMEQYMQIKKQYPDAFLFYRLGDFYEMFYDDAIKGSQILELTLTQRNKKAVDPIPMCGVPHHAAQNYIDILVDKGYKVAICEQVEDPKQAKGMVKREVIQLVTPGTIIDESAGEAKENNYLTALHFENDQYGFAYVDLSTGELKVSVLNTIDTILNELISLRTKEIVVDSSVNDDVLNQIKNLKILISEQNDTEDSSEVSFASQDVENSVEVEVIKHLITYLKITQKRALSHLQRAVHYEPSQYLKMDYHAKRNLELLRNLRTQKKSGTLLWLLDSTKTAMGGRLLKQWIDRPLINLKEIEARQSMVENLLTHYFERSGLQEELVNVYDLERLAGKVAFGSVNGRDLIQLRTSLEHIPQIRYIIQELNDDGTFDEIFDKLDPIEDIADLIEQAIEDEPPISVTDGNLIKPGYSQELDEYVDAMKNGKAWLAELEAKERQATGINNLKIGFNRVFGYYIEVSKGNLSKLPEDRYQRKQTLTNAERFITPELKEKESLILGAESKAKELEYKIFTGIRDQIKDEIQRIQELAGAVAALDVLQSFATVSEQGHFVKPELTTDNHSLDIKDGWHPVVEKVMGKQSYIPNDIKMDDDLDVLLITGPNMSGKSTYMRQLALTVVIAQIGCFVPAKSAKMPIFDQIFTRIGAADDLISGESTFMVEMKETNVALMNATRNSLLLFDEIGRGTATYDGMALAQAIIEYVHNNIHAKTLFSTHYHELTILDESLDKLQNVHVGAIEKNGELIFLHKMQEGPADKSYGIHVAKLAGMPDKLLKRADSILNKLESENDFTVDSTESYAEEKHIEEKNENETSEIQEEQLSLFQPEAVSLDSNQSKILKEIKNANLMGMTPMDVMNIVFKWQKELNKKG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RGS17_HUMAN
Sequence: MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGSSSES
What is the function of this protein?
Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2.  Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504).  Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities.  Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 17, RGS17.
What are the subcellular locations of this protein?
Membrane. Synapse, synaptosome. Nucleus. Cytoplasm.
Protein: GPTC8_HUMAN
Sequence: MADRFSRFNEDRDFQGNHFDQYEEGHLEIEQASLDKPIESDNIGHRLLQKHGWKLGQGLGKSLQGRTDPIPIVVKYDVMGMGRMEMELDYAEDATERRRVLEVEKEDTEELRQKYKDYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPALQPIHIQQPATASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIHIIPASAIHPGPFTFHPVPHAALYPTLLAPRPAAAAATALHLHPLLHPIFSGQDLQHPPSHGT
What are the official names of this protein?
G patch domain-containing protein 8.
Protein: EF106_ARATH
Sequence: MASFEESSDLEAIQSHLLEDLLVCDGFMGDFDFDASFVSGLWCIEPHVPKQEPDSPVLDPDSFVNEFLQVEGESSSSSSPELNSSSSTYETDQSVKKAERFEEEVDARHYRGVRRRPWGKFAAEIRDPAKKGSRIWLGTFESDVDAARAYDCAAFKLRGRKAVLNFPLDAGKYEAPANSGRKRKRSDVHEELQRTQSNSSSSSCDAF
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF106.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: VG66_ICHVA
Sequence: MDSITLNAFDVSSAYTGEFVYDLDLNLFNKMLGGDPAPKPTTQPEERPTGRPIPVPRRRVRPRPAEDQLEEPLEELVKDPIGGPRGEQVEEPVEEPVEPEHPRRIPIPRNRSTRHRFLSADSSPPSHDGAVFDFRDRPTVFQKRGRPVRDMGPVRVSYDISTDVDRLMHNLQSMVKESRAVKVSEKDVDSCHEACERKYVGALMTVSSALRTLMVMVPDIKRIDHPQIKLLVNASRNDFVNVCLTESQKQRSLGVTNVYIDGTDQPLTVNLGLDRNDRLKSTLYKMAQLWKYETKMWERFSAAAKGGYDMKDLIEARRLRVERPFEQTSQLVDYLLDSIDDLTITGVERAKLSDWFTLISRYLKLDHQLLVNELTEGYILKEENKVLKERLDSLQVQVRKLQNRDLLDKWK
What are the official names of this protein?
Uncharacterized protein ORF66.
Protein: MFAP1_DICDI
Sequence: MSVASRIRDKLKNNLESSGGHSVVTSGTKVIRYRAGQRPDYAEAEDDQDSHFSNIQNQKSIKEAETNDPRLARFKNRSSNQDEPQSVEERKASRRRHHDDDNDNDTTTTTTTTTSRRIQKTEIIKEDDDNNNNNNNDTKKDHNDDDEDDDRRRRAKERYLKKKEEEEQKQKELEEKQQPFKDIEGESEEEGSSEYETDSEEDDEDEYWDQPPIFRPTFIKKDDRGTIKTDEQWEKEEQEQQAQLEREKEQRKIEAHRKLKDELDRDRKEQEAKELEQKEEEEYDDDEDQDGSKKLLWIQRELERVRLEIHTRLLAEFEKKEFARRRAMTDDQILKEDPSRSRTNIDNSQKKQLKFLQRDYHRGAFFQDDEYIKNKDFSAPTGEDKFNRELLPKVMQVKNFGKAGRTKYTHLKDQDTTEKDSLWNTNYNNKKKYNNNNNNSNSNSSNNNRDYNYRDRDNRS
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the spliceosome.
What are the official names of this protein?
Protein MFAP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MFAP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PR1B1_ARATH
Sequence: MATPPTLPVTNQQAVQSQPPINTPAFRTFFSRLSTSIRDGLSQRRPWTELIDRSSMARPESLTDALSRIRKNLAYFKVNYVAIVSLVLAFSLFSHPLSLLVLIGLLGGWMFLYLFRPSDQPLVVFGRTFSDRETLLALVLSTIVVVFMTSVGSLLTSALMIGVAIVCVHGAFVVPDDLFLDEQEPANAGLLSFLGGSATSAAAAVSGRV
What is the function of this protein?
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
What are the official names of this protein?
PRA1 family protein B1, AtPRA1.B1, Prenylated Rab acceptor 6.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: HKT23_ORYSJ
Sequence: MPIRLHIFVNSARHAINSSAFICRFIAYHLSPLLIHLSYFLIIDILGFVSLVVLRPSNHKYNPRYVDMFFLSTSAVTVIGLATIQMEDLSSSQIAILTLLMFLDSKMFLSFLGLVLESSKQNKHDPENRRVSSVTVCKQSQLEEATPQTPSMNSIDIKKRCLKYLVFVVLAYMIIILVTGSLLVFMYIAHVSSARDVLTRKSINKALFSISVTVSSFTNGGLLPTNESMVVFSSNNGLLLLLIGQILAGSTLFPVFLRLVIWALRGLRLAKAEEPDFMMNNSSAVGFSHLLPNLQTIFLAVVEVAFVAMTVILFCCLNWDSVVFAGLSSLQKITNALFMAVNARQAGENSIDCSLVAPAALVLFMVMMYTPSLTKLFSACQDHKRIGPESDDRTSKGKPFLKMMAFSPLGFNTTVIMLVCITERRSLSTDPLNLSTFNIIFEVISAYGNIGLSTGYSCSRQLQHQEGIACHEKAYNFSGWWSEPGKLILVLAMLCGRLNSKDSTSARTR
What is the function of this protein?
Probable cation transporter.  May be involved in regulation of potassium-sodium homeostasis.
What are the official names of this protein?
Probable cation transporter HKT2;3, OsHKT2;3, Probable cation transporter HKT3, OsHKT3.
What is the protein family that this protein belongs to?
Belongs to the TrkH potassium transport family. HKT (TC 2.A.38.3) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ADCS_ORYSJ
Sequence: MAALRLPTPPPPRAPAPWLHSSHRRRVAAPRGAGGGGGGGGAVPPPPVRTLLIDNYDSYTYNIFQELSVVNGVPPVVVRNDEWTWRDVYRWVYKERAFDNIVISPGPGSPACPSDIGIGLRILCECGDIPILGVCLGHQALGFVHGAKIVHAPEAIHGRLSELEHNGCYLFNHIPSGINSGFKVVRYHSLVIEPDSLSEDLISIAWTASPKMLSFLESDKPDITSSTLWGSLDNLFVTNQSECSTTDGKMPSINDASELDGYRVLMGVRHSTRPHYGVQFHPESVATHYGRQIFQNFKKITTDFGLQTPLLQERKVHSIGKLERSQISSPDLKNFVANDLLHSARLKLWDSVGPCALPKRSSGDKCLRLQWKKIDNFLNRIGGSENIFSVLFGHHSAEDTFWLDSSSVDQNRARFSFMGGKGGPLWKQMTFHLASQRANCGGNLTIRDAYGCTVRNFLKDGFLDFLDKEMQSIQYIEKDYEGLPFDFHGGFVGYIGYGLKVECDASSNSAKSSTPDACFFFADNLVVVDHNNGDVYILSLHDEYSSGNGDGDYQNSIHSLWLANTEKKLLRMDAMAPRLSINGNSSINGNSFTISSSVNKQRFVIEKSKDEYIRDVQSCLDYIRDGESYELCLTTQMKRRTDYMDALKLYLKLRKQNPAPYAAWLNFSSENLSICCSSPERFLRLDRNAILEAKPIKGTIARGRTPEEDECLRLQLKYSEKDQAENLMIVDLLRNDLGKVCEPGSVHVPRLMDVESYKTVHTMVSTIRGTKMSDLSPVDCVKAAFPGGSMTGAPKVRSMEILDSLETSPRGIYSGSVGFFSYNKTFDLNIVIRTVVLHNGEASIGAGGAIVALSDPEAEYNEMLLKAKAPTKVVEECSQQIYNPDRSDSMQTTVS
What is the function of this protein?
Bifunctional enzyme that catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine.  In the first step, a glutamine amidotransferase generates ammonia that is channelled between the binding sites of glutamine and chorismate and used along with chorismate in the second step, catalyzed by aminodeoxychorismate synthase, to produce ADC.  Required for the synthesis of 4-aminobenzoate (PABA), an important component in tetrahydrofolate biosynthesis.  Does not possess ADC lyase activity (By similarity).
What are the official names of this protein?
Probable aminodeoxychorismate synthase, chloroplastic, ADC synthase, P-aminobenzoic acid synthase, PABA synthase, Para-aminobenzoate synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the anthranilate synthase component I family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: STAD_HELAN
Sequence: MAIRINTATFQSDLYRSFAFPQPKPLRSPKFAMASTIGSATTKVESTKKPFTPPREVHQQVLHSMPPQKIEIFKSMEGWAENNILVHLKPVEKCWQAQDFLPDPASDGFMEQVEELRARAKEIPDDYFVVLVGDMITEEALPTYQTMLNTLDGVRDETGATLLLGLVWTRAWTAEENRHGDLLHQYLYLSGRVDMRQIQKTIQYLIGSGMDPRTENSPYLGFIYTSFQERATFISHGNTARHAKEHGDVKLAQMCGIIAADEKRHETAYTKIVEKLFEIDPDGTVLAFADMMRKKISMPAHLMYDGRDDNLFENFSAVAQRLGVYTAKDYADILEFLVGRWKVADLTGLSGEGRKAQDYVCGLAPRIRRLEERNSARAKESVNVPFSWIFDREVKL
What is the function of this protein?
Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain.
What are the official names of this protein?
Stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic, Stearoyl-ACP desaturase, Acyl-[acyl-carrier-protein] desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid. Note=In green tissue, found in chloroplasts. In non-photosynthetic tissue, found in plastids.
Protein: T23O_BRADU
Sequence: MTSSDYDPASEGAETDFSRRMSYGDYLALDAILGAQHPLSEAHDEMLFIIQHQTTELWMRLAIHELSAARRAIARDEVQPAMKMLARMSRIFEQLNNAWDVLRTMTPSEYTRFRSQLGQSSGFQSRQYRLIEYLLGNRNHAMLKPHAHDAEVTKLLEAELATPSLYDEVLRLADRNGLTMPAAVLSRDVRETHSFNEGVLQAWRVVYEAPETHWMLYELAEKLVDFEDYFRRWRFNHVTTVERVIGFKRGTGGTGGVSYLKRMLEVELFPELWRVRTIL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: RIMP_SHESH
Sequence: MATIENRLEEMLKSPVEALGHTLWGLEYVQAGKHSILRVYIDNEKGIFIEDCAETSRQVSAVLDVEDPISTEYTLEVSSPGVDRPLFKAEQYAAYIDETVKIQLTMPVAGSRNLKGTITGIEGQMLSLTVDGNELIIALDNIRKGNLIAKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_BOWSE
Sequence: MSRRSTAEKETAKSDPIYRNRLVNMLVNRILRHGKKSLAYRILYRAMKNIQQKTEKNPLSVLRQAIRGVTPNVTVKARRVGGSTYQVPIEIRSTQGKALAIRWSLGASRKRPPGRNMAFKLSYELMDAARENGNAIRKKEEAHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FCY2_YEAST
Sequence: MLEEGNNVYEIQDLEKRSPVIGSSLENEKKVAASETFTATSEDDQQYIVESSEATKLSWFHKFFASLNAETKGVEPVTEDEKTDDSILNAASMWFSANMVIASYALGALGPMVFGLNFGQSVLVIIFFNIMGLIFVAFFSVFGAELGLRQMILSRYLVGNVTARIFSLINVIACVGWGIVNTSVSAQLLNMVNEGSGHVCPIWAGCLIIIGGTVLVTFFGYSVIHAYEKWSWVPNFAVFLVIIAQLSRSGKFKGGEWVGGATTAGSVLSFGSSIFGFAAGWTTYAADYTVYMPKSTNKYKIFFSLVAGLAFPLFFTMILGAASAMAALNDPTWKAYYDKNAMGGVIYAILVPNSLNGFGQFCCVLLALSTIANNIPNMYTVALSAQALWAPLAKIPRVVWTMAGNAATLGISIPATYYFDGFMENFMDSIGYYLAIYIAISCSEHFFYRRSFSAYNIDDWDNWEHLPIGIAGTAALIVGAFGVALGMCQTYWVGEIGRLIGKYGGDIGFELGASWAFIIYNILRPLELKYFGR
What is the function of this protein?
This permease has a broad specificity towards purines, and also transport cytosine and 5-methylcytosine but neither uracil nor thymine.
What are the official names of this protein?
Purine-cytosine permease FCY2, PCP FCY2, Cytosine/purine transport protein FCY2, Fluorocytosine resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the purine-cytosine permease (2.A.39) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EIF3K_MOUSE
Sequence: MAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLTDNQLKVWMSKYGWSADESGQVFICSQEESIKPKNIVEKIDFDSVSSIMASSQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, Eukaryotic translation initiation factor 3 subunit 12, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HIS6_METMA
Sequence: MLTKRIIPCLDVTLDRAGGCVVKGVEFVDLKEAGDPVELAKRYNEDGADELVFLDITASAHGRETMIDVIERTADEVFIPLTVGGGISSIEAIRQILRAGADKVSVNTSAVKNPEFIKESSDIFGAQCIVTAIDCKRNTNVKDNPDKTILELEDGTPAWYEVVIYGGRKNTGIDAVQWAKRAEELGSGEILLTSMDRDGTCAGYDIPITRKLSEELDIPIIASGGVGNPQHIYEGFSDGKADAALAASIFHFGEYSIQEVKEFLKERKIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_ALKCK
Sequence: MTKGILGRKIGMTQVFAENGEVIPVTVIEAEPNIVLQKKTVESDGYEAIQIGFADAKKPNKPATGHAAKAETAPKRFIKEIRGVNLDEVEVGQAINVTTFAAGDLVDVTGTSKGKGFQGAIKRHNQSRGPMSHGSRYHRRPGSMGPVAPNRVFKGKALPGRMGGEQITMQNLEIVRVDEERNLLLVKGNVPGAKKSYVTVQSAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PSA_HALWD
Sequence: MQGQAQQQAYDRGITIFSPDGRLYQVEYAREAVKRGTASVGIRTPDGIVLAADKRSRSPLMEPTSVEKIHKTDDHVGIASAGHVADARQLIDFARRQAQVNRLRYGEPVGIETLTKNVTDNIQQYTQVGGARPFGVALLIGGIEDGSPRLYETDPSGTPYEWKAVSIGADRSDLQEHLEENYTEELSLDEGVGLALRTIAISNDDELTAAGVDVATVASDTEEFIELTNDEISAYIADNDLEPAEETDSE
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_ECOUT
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTANDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LBX1_HUMAN
Sequence: MTSKEDGKAAPGEERRRSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLLAAADKHAQGGLPLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPGAPKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEEIDVDD
What is the function of this protein?
Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.
What are the official names of this protein?
Transcription factor LBX1, Ladybird homeobox protein homolog 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_SALA4
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLDDEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ACPS_HERA2
Sequence: MLVTGVDLIEIDRINQAVSRWGQRFARRVWTEAEWLRCRDSAQSLAARWAAKEAAAKALGVGLKGIGHPACAVAWREIEVANDTQGKPLLRLHGAAQQRANELGIRHWSVSLSHSGDQAIAFVVGMG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.