PharMolix/UniProtQA huggingface dataset:
Protein: NTH_MOUSE
Sequence: MNSGVRMVTRSRSRATRIASEGCREELAPREAAAEGRKSHRPVRHPRRTQKTHVAYEAANGEEGEDAEPLKVPVWEPQNWQQQLANIRIMRSKKDAPVDQLGAEHCYDASASPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVESILQTDDDTLGRLIYPVGFWRNKVKYIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTISGIAVDTHVHRIANRLRWTKKMTKTPEETRKNLEEWLPRVLWSEVNGLLVGFGQQICLPVHPRCQACLNKALCPAAQDL
What is the function of this protein?
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage.  The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site.  The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination.  Primarily recognizes and repairs oxidative base damage of pyrimidines.
What are the official names of this protein?
Endonuclease III-like protein 1, Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase, DNA glycosylase/AP lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: RL35_ALISL
Sequence: MPKMKSNKGASKRFKKTAGGIKFKHATKRHILTKRTTKNKRQLRPNSLLAKCEVAAVLRMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RNS7_NICAL
Sequence: MLNSPLTSVLFVLLFVLSPIYGAFEYMQLVLQWPTAFCHTTPCKRIPNNFTIHGLWPDNVSTTLNYCAAKENFKNIEDDTKKDDLYKRWPDLTTAETYCKQHQNFWRHEYNKHGKCCSESYNREQYFDLAMALKDKFDLLSSLRNHGIIPGRGMKYTVQKINSTIKKITQGYPNLSCTKGIMELVEIGICFDSMVKNVINCPHPKTCKPTGSNEIKFP
What is the function of this protein?
Self-incompatibility (SI) is the inherited ability of a flowering plant to prevent self-fertilization by discriminating between self and non-self pollen during pollination.  In many species of the Solanaceae, self-incompatibility is controlled by the single, multiallelic locus S.  This stylar glycoprotein is associated with expression of self-incompatibility in potato.
What are the official names of this protein?
Ribonuclease S-7, S7-RNase, Stylar glycoprotein 7.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: MUKF_MANSM
Sequence: MLETSQTIPELVSWAKEREFSLNLPTERLAFLLAIAIYNAERFDGEMVESDLVDIFRHVSNEFEQSKETIATRANNAINELVKQRFLNRFSSEFTESLSIYRLTPLGVGVSDYYIRQREFSALRLSVQLAIVANEIQRASELAEEGTAKQEDEYYWRRNVFAPLKYSVAEIFDSIDLSQRIMDENQQSIKEEIAELLTKDWQAAIASCERLLDETSGNLRELQDTLNAAGDKLQEQLLRIQDCVIGRDDLYFIDQLITDLQAKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFSQRLRQSIHNYFDMPWYLWTAQAERLIDLRDEELALRDEDALGELPEELEYEQLSDLHDQIVDYMQNLLIAQRERNQPIDLSLVLKEQLEGYPLARHFDVARIIVDQAVRLGMASADLSGTYPQWQEINNRGAEVQAHVIDEYK
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: PYRH_CHLCV
Sequence: MSKRITRVLFKISGESLSTDSGNRIDEVRLSRLVSELRAVRNSDIETALVIGGGNILRGLAQQKELQINRVSADQMGMLATLINGMAVADALKADDIPCLLTSTLSCPQLADLYTPQKSEEALSQGKVLICTTGAGSPYLTTDTGAALRACELKADILLKATMHVDGVYDKDPLMFTDAVKYDRISYKDFVAQGLGVMDVSAVSLCMDSNIPIRVFSFVKHSLEQAIFDENIGTLICGDA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_STRPN
Sequence: MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPDFWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAELDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKVEVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVEVMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRTQYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDHRTSFEVAQVDKVMDGDLDGFIDAYLKWRIS
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAXB_PASAE
Sequence: MEPLMSFKQKNDYGLHALVILAQYHNIAVSPEEIKHKFDPEGKGIDLVAWLLAAKSFELKAKKVKKSIDRLPFIHLPALIWRDDGQHFILTKIDTQTNRYLIFDLEERNPKVLSAVEFQQVFQGNVILLTSRASIMGKLAKFDFTWFIPAIIKYRKIFVEVMIVSIFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALAIVVIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLALPISYFENRRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTIVILLSLPCYIAWSIFISPILRRRLDEKFTRNADNQAFLVESVTAIDTIKALAVTPQMTNIWDKQLASYVSADFRVTVLATIGQQGVQLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGISITRLGDVLNAPTENFQGKLSLPEINGDVTFKNIRFRYKPDAPIILNDVNLTIKQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIRDNIALTDPSMPMEQVIHAAKLAGAHDFISELREGYNTMVGEQGAGLSGGQRQRIAIARALVNNPRILIFDEATSALDYESEHIIMRNMQQICHGRTVIIIAHRLSTVRKADRIIVMEKGHIVERGKHSELLENKDGLYYYLNQLQSI
What is the function of this protein?
Part of the ABC transporter complex PaxBD involved in PaxA export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable).
What are the official names of this protein?
Exotoxin translocation ATP-binding protein PaxB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y929_THEMA
Sequence: MKGEETLKKALLNIGKESPFYYYVLLGVKLVPSKNTRNLKLSFSTTGDVMLLYNPEAIGKKPLRMVQALLIHEVMHIVLQHFRIKPKDERDRKIWDLAMDAAINQYIPELAAFGVPLDVLVKEGHTTDNDTLFVLPPEWMMFENAEMYHKWILEEMERLGRYDVEVVAEFRDNVDDHSGLFEEDVPVEMILDLTKDRTKKAFNLFGNTLPSGVRREVSLSLENPELDWKTLLRRFFGVSIKADRYTTPLRPNRRYDHLPGWRNEYLPRIAAVVDTSGSIVEKELNQFISELEKISNIAGEELWLVQVDKSVTSAMKYRSGKWKDLEIVGGGSTDLQPAIDYSERVLRSEGTVVFTDGHTDVPIARRRILFVLSRYHNEEFLKEARKMYGRDAVVVLS
What are the official names of this protein?
Uncharacterized protein TM_0929.
Protein: ITR6_CYCPE
Sequence: ARICPRILMKCKKDSDCLAECICEEHGFCG
What is the function of this protein?
Strongly inhibits trypsin, weakly inhibits chymotrypsin.
What are the official names of this protein?
Trypsin inhibitor 6, CyPTI-VI, Trypsin inhibitor VI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPP1_FRACC
Sequence: MSNIAAPRLPVPGPDLRAPGQGGPAFDDQVFNRLLANRIVFLGSVVEDSIANAICAQLLLLNAEDPTRDIFLYINSPGGSVSAGMAIYDTMQFVENDVATVSLGLAASMGQFLLCAGASGKRYSLPHARIMMHQPSGGIGGTASDIAIQAEQMLYTKRMMQERIAFHTGQPIEQIERDSDRDRWFTAEEAKDYGFVDHVVQQARQVPSEGPVS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CERU_SHEEP
Sequence: MKIFLLCIFLILCGTSVWAKDKHYYIGIIETAWNYASDHAEKKLISVDTEHSNIYLQNGPNRIGSVYKKAVYLQYTDENFRTVIEKPVWLGFLGPIIKAETGDKVYVHLKNFASRPYTFHAHGLTYYKEHEGAIYPDNTTDLQKADDKVQPGEQCLYILHANPEQGPGEEDSNCVTRIYHSHIDAPKDIASGLIGPLIHCKKDSLDEEKEKNIDKEFVVMFSVVDENLSWYLEENIKTYCSEPEKVEQDNEDFQESNRMYSVNGYAFGSLPGLSMCAEDRVKWYLFGMGNEIDVHAAFFHGQVLTSKNYRVDTINLFPATLFDAFMVAQNPGQWMLSCQNLNHLKAGLQAFFWVQDCKKSSSEDNIHGKNVRHYYIAAEEVIWNYAPSGIDAFTKENLRAPGSASEAFFEQGPTRIGGSYKKLVYREYTDASFSNQKERGPEEEHLGILGPVIAAEVGDTIRVTFHNKAAHPLSIEPIGVRVDKNNEGTYYSPTGSGPPPSGSHVAPKGTFTYEWTVPKEVGPTYKDPVCLAKMYYSGSTKDIFTGLIGPMKICRNGSLLANGRLKNVDKEFYLFPTVFDENESLLLDDNIKMFTTAPDQVDKENEDFQESNKMHSMNGFMYGNQPGLSMCQGDSVMWYLFSAGNEVDIHGIYFSGNTYLSRGERRDTANLFPQTSLSLFMQPDTAGTFDVECLTTDHYTGGMKQKYTVSQCGQRSEDLYLYLGERTYYIAAVEVEWDYSPSRKWEKELHHLQEQNLSNAFLDKEEFYIGSKYKKVVYRQFTDSTFQVPVERKGEEEHLGILGPQLHADVGDKVNIIFKNMATRPYSIHAHGVKTESSTVTPTAPGETRTYIWKIPERSGAGMGDSPCIPWVYYSTVDRVKDLFSGLIGPLIVCRKHYLKVSNPIKKLEFSLLFLVFDENESWYLDDNIKTYSDHPEKVDKANEEFMESNKMHAINGRMFGNLQGLTMHVGNEVDLHSVHFHGHSFQYQHRGIYTSDVFDLFPGTYQTLEMTPKTPGIWLLHCHVTDHIHAGMETTYTVLPNEEIKSG
What is the function of this protein?
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein.  It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species.  It is involved in iron transport across the cell membrane (By similarity).
What are the official names of this protein?
Ceruloplasmin, Ferroxidase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: TJB27_HUMAN
Sequence: SYEQYFGPGTRLTVT
What is the function of this protein?
J region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta joining 2-7.
What are the subcellular locations of this protein?
Cell membrane.
Protein: LPTD_COXBU
Sequence: MKQGKSFIFYCLVLLLCGFQQLSSAVTASIAKAIKTTDRKQRVSETLPTGLSYRRFYQHIAHLLGWVPAPDLVCRGYFKEPLILTEHPHPGPATKEPAIVTAKGPSMVTAQGVSILRKDVVVTQPGRIVEADKAYIYRDSKTGHVTKIILIGHVRLHEADKRIVADKGTLTLYPKTAILMNAAYHIYNGEPYFYKFKYPFDAWGIAKHAVRDASNVITLRHATYSTCKPTAPAWSMSATTLVLNRNTHRGEAYNMLLHIGRVPIFYFPYFNFPIDNYRKTGFLIPYAGHSSSSGWFFALPFYWNMAPNYDLTLTPEFMSERGLNLQSLFRFLSTKSSGTIYLNYLPNDKVFQQFRETTLSKFPPSVLAEHPVFIPYVDKLKKMKNQRAFFSMNETTLFNSEWSSRVILNYVTDPYFFQDLGGQLGGSSLANQLLNQIDLQYNGLHWQFMGMLQAYQTLHLISQWTTPALDQYSRLPDFNIVGYYPDIARHVDFNFNAEAVNFDYRSDFVPDKPRGQRFHMRPGISFPFYFASGYIIPQLWADATAYNITHFQPGQAHTSSRLLPIFDIDSGLYFDRNFHLGHRSFIQTLEPRFFYLYVPYQNQDRFPNFDTVLLPFSFEQLFALNQFTGNDRLQNANQASFALTSRVLDAQNGSPILTANVGFIYYLENQRVCLTPGCTPSNYHYSPIIGELTFYPFPYWSFTGSLAWDPNLGQTNNTSVELAYNNGGKKADIRYLFVHGNEDSIVTPTTLIVPGNAYSQNTNHVISSGAWPLLKKWNAVGYWDYNITERRTDVYSIGVQYNTCCWALSFSIRRTYAGLKVDPNGALQRQYDTAYGFELQLKGLGNLGTAPISTVTVLDAMNNGVSNDVR
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: Y4098_METAC
Sequence: MTDIEIYRKRLERIEELLLELSEYSKKGAVIIVEGKRDILSMKRLGIDGNFELATRHSLFNFSERIAKLGCEVIILTDWDRRGDILATKLSEYFGNFGIKPELQIRNKLRLITQKEIKDVESLYTYVSKLRSKTGVSFDQEDNI
What are the official names of this protein?
UPF0292 protein MA_4098.
What is the protein family that this protein belongs to?
Belongs to the UPF0292 family.
Protein: DUT_SHEPA
Sequence: MKTPIELKILDSRIGTEFPLPAYATPGSAGMDLRAITDTQLVIQPGETVLIPTGIAIHVADPSLAAIILPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVSCWNRGSEPFTIEIGDRLAQLVFVPVVQAEFKLVDEFNQSDRGAGGFGHSGTK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PEPX_STRPD
Sequence: MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKNHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFEGKANQALVDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_RICCK
Sequence: MTKLIIHLVSDSSVQTAKYAANSALAQFTSIKPKLYHWPMIRNLELLNEVLSKIESKHGIVLYTIADQELRKTLTKFCYELKIPCISIIGKIIKEMSVFSDIEIEKEQNFNYKFDKTYFDTLNAIDYAIRHDDGQMLNELPEADIILIGPSRTSKTPTSVFLAYNGLKAANIPYVYNCPFPDFIEKDIDQLVVGLVINPNRLIEIREARLNLLQINENKSYTDFNIIQKECLEVRKICEQRNWPVIDVSTRSIEETAALIMRIYYNRKNKYNK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: PPIL3_CRYNJ
Sequence: MSVTLHTNLGDIKIELFCESVPRTAENFLALCASGQYDGTLFHRNIRGFMIQGGDPTGTGKGGQSIWGRPFSDEIRQTLRFNNRGMVAMANAGPDTNKSQFFITYAKQPSLDGKYSIFGKVIDGMETLDSMEKTPVNPKSRPLQEIKLLNVTVHANPIADQAKGGLA
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 3, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.
Protein: HEMH_MARMS
Sequence: MKNTSDYGVLMMNLGTPDAPQTPEVRRYLREFLSDSRVVDLNPLIWKPILNLIILTIRPPKVAKIYQQVWMDEGSPLLVLSERLKEKVKEALSEKKGQTVPVELAMTYGNPSVEVAANKLREQGVKNIIVIPMYPQFSATTTAAAYDRLMKSLKNCPHWPSLQLLHDYADHPMYIKALSNSVRAQWDKQGERRHLVLSYHGIPKRYVTNGDPYARRCETTSRLVAEELELGDHEWTHVYQSRFGREEWLKPYADATLKALPSMGVKKINIISPAFSIDCIETLEEVTLELGDEFKNNGGLAFDYIPALNDTPDQVALYVNLIEQNSKQWT
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_VIBCM
Sequence: MSQSLRIVFAGTPDFAARHLAALLSSEHEIIAVYTQPDRPAGRGKKLTASPVKTLALEHNVPVYQPENFKSDESKQQLAALNADLMVVVAYGLLLPKVVLDTPKLGCINVHGSILPRWRGAAPIQRSIWAGDSETGVTIMQMDVGLDTGDMLKIATLPIEASDTSASMYDKLAELGPQALLECLQEIAQGTAVAVKQDDALANYAHKLSKEEARINWNDEAAHIERCIRAFNPWPMSHFEVAENSIKVWQARVETRAVTQTPGTIIQADKSGIYVATGQDVLVLESLQIPGKKALPVQDILNARADWFSVGSQLS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y1796_GRAFK
Sequence: MFGDMMGMMNKLKEAQEKVEATKKRLDTVLVDEQSSDGLLKITITANREVKNISIDDKLLEDKEQLEDYLVLTMNKAIEKATNINEAEIGAAAKDGMPDIPGMDGLMK
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein GFO_1796.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL13_MYCMM
Sequence: MPTYAPKAGDTTRSWYVIDATDVVLGRLAVAAANLLRGKHKPTFAPNVDGGDFVIVINADKVAISNEKLRNKMAYSHSGYPGGLRKRSIGELMEKHPDRVVEKAIVGMLPKNKLSRQIQSKLRVYAGPEHPHTAQQPVPFEIKQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: END4_ESCF3
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVAEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTEGVTAVIENTAGQGSNLGFKFEHLAAIIAGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFAEFERIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RR11_ANEMR
Sequence: MPNSMEEMNLRRSRRRLPRGVIHIQASFNNTIITVTDTRGRVVSWSSAGACGFKGARKSTPFAAQTAAENAIRILIDRGLKQAEVMISGPGPGRDTALRAIRRSGIVLNFVRDVTPMPHNGCRPPGKRRV
What are the official names of this protein?
30S ribosomal protein S11, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid.
Protein: ATPA1_BURMA
Sequence: MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDIVKTTGRILEVPVGPELVGRVLDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQCGKTAVAIDTIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPYAGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKDVLPFEKGLREYLKTSHADLIKRIEDTKDLSKDDESALHAALKDFKKSGAY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PIMT_CAUVN
Sequence: MSGGTTKAAENAKADLPRLMKALRDQGVTDPQVLKAIETTPRDLFTPDLFKDRSWEDSALPIACGQTISQPYIVGLMTQALTVEPRSRVLEIGTGSGYQTTILSKVSRLVYTIERYRTLMKEAEARFNTLGLTNVITKFGDGGEGWAEQAPFDRIMVTAAAEDDPKRLLSQLKPNGVLVAPVGKGPVQSLRRYAGDGKGGFRVEILCDVRFVPLLAGVAKDQ
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_CHLCH
Sequence: MANINFGFEHHAKKLYSGAIEQGISNSLVPMVIETSGRGERAFDIFSRLLRERIIFLGTGIDEHVAGLIMAQLIFLESEDPERDIYIYINSPGGSVSAGLGIYDTMQYIRPEISTVCVGMAASMGAFLLASGNKGKRASLPHSRIMIHQPSGGAQGQETDIVIQAREIEKIRRLLEELLAKHTGQPVEKVREDSERDRWMNPQEALEYGLIDAIFEKRPTPEKKD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBD2_YEAST
Sequence: MTPTNQSSGTTNASVEVLSEDGPMPINVMMQEGVKALTKILSNQLQDRQAFQNAPHAMQFVIRNGGKALSNARLEELKDALPKMDSLSLEDELAKIDGQSAYHIDSAEEKETFESKIGQIASRNSADFIIEEDLQNILDDDLKDSELNLDGEEAEIIFDYESQELDTPDGIGEKISQMIESVLPGGFGSEEQGGLRTVTNVEDLDVAEEVTDIDHDTVDAARLHGDGQHSISSRKHSRSKNSKKNGHVRRHDFYDESRDHKSCCPHHHYENLSKLRNYYYHDFEYISRTENRVPDFSVLVNESSPMCLFCEYYMVFGEPPRNMIKWYNRTFGYNRMPNPPRDEQDSRKRNR
What is the function of this protein?
Part of a checkpoint which monitors spindle integrity and prevents premature exit from mitosis.  This cell-cycle arrest depends upon inhibition of the G-protein TEM1 by the BFA1/BUB2 complex.
What are the official names of this protein?
Protein IBD2, Inhibition of bud division protein 2.
What is the protein family that this protein belongs to?
Belongs to the IBD2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle pole.