PharMolix/UniProtQA huggingface dataset:
Protein: BRKP1_PITAZ
Sequence: MSFLKKSLFLVLFLGLVSSSICEEEKRETEEEENEDEIEEESEEKKREDPERPPGFTPFRVY
What is the function of this protein?
Inhibits ACE with a Ki of 1. 6 uM, and targets B2 bradykinin receptor (BDKRB2).  Provokes contraction of smooth muscle preparation (ileum).  In vivo, induces an early hyperalgesic effects in living rats after intraplantar injection (By similarity).
What are the official names of this protein?
Phyllokinin-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Bradykinin-related peptide subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: INP_BACTN
Sequence: MKRPSFLPVLIGTGFGSGFSPFAPGTAGALLASIIWIALYFLLPFTALLWTTAALVVLFTFAGIWAANKLESCWGEDPSRVVVDEMVGVWIPLLAVPDNDRWYWYVIAAFALFRIFDIVKPLGVRKMENFKGGVGVMMDDVLAGVYSFILIAVARWVIG
What is the function of this protein?
May be responsible for the conversion of phosphatidylinositol phosphate diacylglycerol (PIP-DAG) to phosphatidylinositol diacylglycerol (PI-DAG), making it a key enzyme in the inositol glycerophospholipid biosynthesis pathway.
What are the official names of this protein?
Putative phosphatidylinositol-3-phosphatase, Phosphatidylinositol phosphate phosphatase, PIPPh.
Protein: RL22_MACCJ
Sequence: MEAKAVARTIRIAPRKVRLVLDLIRGKEVAEAIAILKLTNKASSPVVEKLLMSALANAEHNYDMNIDSLVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVADKEVKTSNTEAQEEAK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: HSLU_BACCQ
Sequence: MHLHFTPRQIVEKLDQYIIGQKDAKKAVAVALRNRYRRSKLAENLRDEIAPKNILMIGPTGVGKTEVARRMAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSVRIVKEEMVVKVQDKAEEQANQRLVEILVPSPEKQSGFKNPLEMLFGGAQNSNQTTDSQEDVEIEKKRQDVERKLAAGLLEDEIVSIEVTEQQSSMFDMLQGTGMEQMGMNFQDALGSFMPKKTKKRKLSVKEARKVLTNEEAQRLIDMDEVTQEAVYRAEQLGIIFIDEIDKIAGKQSNSVDVSREGVQRDILPIVEGSNVATKYGSVKTDYILFVAAGAFHMSKPSDLIPELQGRFPIRVELTKLSTDDFVKILIEPDNALIKQYIALLATEGIEIEFSDEAIRKIAEIAYQVNQDTDNIGARRLHTIMEKLLEDLSFEASEITLEKITITPQYVEEKLATIAKNKDVSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C724B_ORYSJ
Sequence: MVGGELVLAALVILLALLLTLVLSHFLPLLLNPKAPKGSFGWPLLGETLRFLSPHASNTLGSFLEDHCSRYGRVFKSHLFCTPTIVSCDQELNHFILQNEERLFQCSYPRPIHGILGKSSMLVVLGEDHKRLRNLALALVTSTKLKPSYLGDIEKIALHIVGSWHGKSKDKGMVNVIAFCEEARKFAFSVIVKQVLGLSPEEPVTAMILEDFLAFMKGLISFPLYIPGTPYAKAVQARARISSTVKGIIEERRNAGSSNKGDFLDVLLSSNELSDEEKVSFVLDSLLGGYETTSLLISMVVYFLGQSAQDLELVKREHEGIRSKKEKDEFLSSEDYKKMEYTQHVINEALRCGNIVKFVHRKALKDVRYKEYLIPSGWKVLPVFSAVHLNPLLHGNAQQFQPCRWEGASQGTSKKFTPFGGGPRLCPGSELAKVEAAFFLHHLVLNYRWRIDGDDIPMAYPYVEFQRGLPIEIEPLCSES
What is the function of this protein?
Involved in brassinosteroid biosynthesis (PubMed:15705958, PubMed:16369540).  May catalyze a C6-oxidation step and may be involved to supply 6-deoxotyphasterol and typhasterol (PubMed:15705958).  Involved in internode elongation and seed development (PubMed:15705958).  Catalyzes the conversion of campesterol (CR) to (22S)-22-hydroxycampesterol (22-OHCR, 22-hydroxyCR) (PubMed:16369540).
What are the official names of this protein?
Cytochrome P450 724B1, OsCYP724B1, (22S)-22-hydroxycampesterol synthase, Dwarf protein 11, OsDWARF11.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYFA_BARQU
Sequence: MNDIERLEKEICLALEAASDEQTLETVRIAALGKKGCISEKLKALGKMDVEERHKVGPVLNGLKNRVLELWVQKRDLLRRQAMNKRLSRETVDVTLPVRSSPLERGRIHPISQVIEEIIAIYANMGFSLAEGPDIETDYYNFTALNFPEGHPAREMHDTFFFDVDKTGERKLLRTHTSPVQIRTMEKQKAPIRIIIPGKTYRMDSDATHSPMFHQVEGLVIDKTSTIAHMMWLHETFCKAFFEVPSVKMRFRPSFFPFTEPSMEVDIQCDRSGSKVKFGEGQDWLEILGCGMVHPYVLQNVGLDPDVYQGFAWGMGIDRIAMLKYGMPDLRAFFDADLRWLDHYGFRCFDMPAFFPGLRNE
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_BRUA1
Sequence: MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTQAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKGNVSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ENO_CAUSK
Sequence: MTEIVDIIAREILDSRGNPTVEVDVVLEDGAFGRAAVPSGASTGAHEAVEKRDGDKSRYGGKGVKSAVDAVNGELFDALSGVDAEDQRRIDNLMIALDGTPNKSRLGANAILGVSLAVAKAAAESAGLPLYKYVGGVSARVLPVPMMNIINGGAHADNPIDIQEFMILPTGSPTFAEALRMGAEIFHGLKKALKDAGHNTNVGDEGGFAPNLGSAEDALAFIVKAGEAAGYKSGEDFVLGLDVAATEFFKNGKYELEGEGKSLDPAQMVDYLAGLADKFPILSIEDGMSEDDFDGWKLLTDKLGKKVQLVGDDLFVTNPKRLQIGLDKGLANSILIKVNQIGTLSETIDAVDMAHRAAYTSVMSHRSGETEDSTIADLAVALNCGQIKTGSLARSDRLAKYNQLLRIEEALDDQAVYAGRAVLKGR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: OPSD_CORAU
Sequence: CGIDYYTRAPGYNNESFVIYMFIVHFLIPLFIISFCYGNLLCAVKAAAAAQEESETTQRAEREVTRMVIMMVISYLVSWVPYASVAWYIFSNQGSEFGPVFMTIPAFFAKSSALYNPLIYVLMNKQFRHCM
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: Y1154_METLZ
Sequence: MQIRYAGHSCFIIEGSKKLLFDPMPLEDPAAVEADLTLISHAHADHIGDAFARFSLTIAVHELSGYLKSLGVKTIGMNIGGSVEWEGITVRMVPATHSSSIRQKDGTSLYMGQACGFVVEMDGHVIYYAGDTGLFSDMKLIRELYHPDIAILPAGGRYTMGPEECMMAAAWIGAKTVIPMHVNTYPEIEQDMPAFKRAIELTTVMHVEIMQPDDVLELP
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Mlab_1154.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: ELG1_DROME
Sequence: MTDVNCLTSEHIAPTTTTASPPGTPSKNAATDPVEPTSPFVLRAPPSAKSKLILQNMEEVLNSVKQKHREKHKRKREEKRRAALMEDQKSTTEEVKANAKEKPQPLREKSSQENGLKNGRRRSSPLKSSTPVADNQSIMKHFAKAGKPENVGVSPVSTAKPKPTTNVFEFMMNARNRSLGVNEGGAESPADQEIGSEAATPTTKRKLLLQEWNERKGGAKRRLADEARGEFIELQMEQRAKRLRKMLTKTDAKEVTAPSSAPTDPTVKRLRGRPRSRRISSMDAQNQIVESKPPVVKAKDQDPGTEELLSKLSSPTKKRDSLLGYFPKVESPKELAEKVIIAIETPPMETPKRRTLRRKSQQETPIVAESTPSSRPRRSCVGKARYDYDLETSPGKQQKAKPQKADESVEIIDLDNSNPAATPKKLAPLFVRQLPKPSPDPSVLKARQAFLQSGVPDKIRQEQIRQKNFDQMYEDSYEVFPRLAHIGCESFGSKNGPLDIPFALRAEEEYSEVTKALPANKRRAKASSITSCLPADFTSSKTLNKFNYATLPQLENKRGFVKLWKNDFDRFPTFKCYNQMREKYRHFSAIDSAQDTQQMGESLVVTRRTRRSMEQNMAQNEEEAKPPPSAPNGELLFTEKYKPLLFEQVLVNLTPVQELREFLSSWSGNGGSNRNSQGMDDTFDMSNDSASMGSSSNTMVLVGPSSSGKTNAVFTLANDMNFNVLEINAGMKRTGKKLIQELQEATQSHQIRKDGKAGGGSSQQLLQKLQKSGLKAKAAAVEPPSEVRKSLILIEDADILFDNLDAGFTDAIYTLAASSKRPVIVVATDPNCAHLQRLMQQNIIHFQAPNALNISRFLAVLSLMENCPIELDELISVYLYNQQNLRKTLMELQFYIQSGGDSTRDRTGGGIKSPTKTSNSRLATVDGSRIHQRFFEFFTSPQNVQYRIPFPVDFSLLRLNLPDLMASSAMLKEQQAAGGGSRTAAKRKSRSPKKAWLSSATGQKSDGHSSSLATLASFYDNISVASLMDSDCSDRLQWHLSEEIGHLLVEQALQTGLATKECPYNLFDKPVQRFSICQHLGNGVLRSDSAKSLDFEPALRSICRSEKERAGLERKSSRFYHYLRNHTVNVTSFTTDYFDTACSTFQSAAPSSEPTMEAEPKD
What is the function of this protein?
Has an important role in DNA replication and in maintaining genome integrity during replication stress (By similarity).  Promotes PCNA deubiquitination (By similarity).  As component of the Elg1 RFC-like complex, regulates the functions of the DNA polymerase processivity factor PCNA by unloading it from DNA after replication during the S phase of the cell cycle (PubMed:27198229).  The PCNA-unloading might be regulated via interaction with the Enok acetyltransferase complex (PubMed:27198229).  Might have a role in restarting of stalled/regressed replication forks during replication stress (By similarity).  In the ovaries, has a role in nurse cell endoreplication (PubMed:27198229).
What are the official names of this protein?
Enhanced level of genomic instability 1.
What is the protein family that this protein belongs to?
Belongs to the ELG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSPB_THEKO
Sequence: MFHQAKWDEPTIFELSRPGRIGYTLPKPIEDVDVDIPEKLRRKSPLNLPELSEPEVVKHYTRLSEMNYGVDSGIYPLGSCTMKYNPKINEEIASHPGVAYVHPYQDEGTVQGALKIMWELEQWLKEITGMDRFTLQPAAGANGEFTGVSIIRAYHIDRGETQRTEMLVPDSAHGTNPASAAMAGFKVIEIPSNENGTVDLEALENAVSERTAGLMLTNPNTLGIFEDEILEIAKIVHKAGGLLYYDGANLNAVLGKIRPGDMGFDVVHLNLHKTFSTPHGGGGPGSGPVGVKDFLKDYLPVPLVSYDAENDRYYLDYNVPRSIGKVKELYGNFAVIVRALTYLKIMGREGLKEVSEVAVLNANYLTQKLKGTRGYELPGKELRKHETVFSAEPMKKETGVKALDVAKRLLDFCMHAPTIYFPLIVHEALMIEPTETVSKEELDAYVEALKRISEEAYSNPEVVTSAPHNTAVRRVDDVLAAKKPVITWRMYRELKERGEIDY
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: DNLJ_GEOKA
Sequence: MDRQQAERRAAELRELLHRYGYEYYVLDRPSVPDAEYDRLMQELMAIEEQYPELKTSDSPTQRIGGPPLEAFRKVTHVVPMMSLANAFDEGDLRDFDRRVRQEVGEAAYVCELKIDGLAVSVRYEDGYFVQGATRGDGTTGEDITENLRTIRSLPLRLKEPVSLEARGEAFMPKASFLRLNEERKARGEELFANPRNAAAGSLRQLDPKVAASRQLDLFVYGLANAEELGIESHSEALDYLQALGFKVNPERRRCANIDEVIAFVNEWHEKRPQLPYEIDGIVIKVDSFAQQRELGATAKSPRWAIAYKFPAEEVVTTLIGIEVNVGRTGVVTPTAILEPVRVAGTTVQRATLHNEDFIREKDIRIGDAVIIKKAGDIIPEVVGVVVDRRDGDETPFAMPTHCPECESELVRLEGEVALRCLNPNCPAQLRERLIHFASRAAMNIEGLGEKVVTQLFNAGLVRDVADLYRLTKEQLIGLERMGEKSATNLLAAIEASKQNSLERLLFGLGIRYVGAKAAQLLAEHFETMERLERATKEELMAVPEIGEKMADAITAFFAQPEATELLQELRAYGVNMAYKGPKRSAEAPADSAFAGKTVVLTGKLASMSRNEAKEEIERLGGRVTGSVSRSTDLVIAGEDAGSKLEKAQQLGIEIWDESRFLQEINRGKR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PGAP4_HUMAN
Sequence: MSTSTSPAAMLLRRLRRLSWGSTAVQLFILTVVTFGLLAPLACHRLLHSYFYLRHWHLNQMSQEFLQQSLKEGEAALHYFEELPSANGSVPIVWQATPRPWLVITIITVDRQPGFHYVLQVVSQFHRLLQQCGPQCEGHQLFLCNVERSVSHFDAKLLSKYVPVANRYEGTEDDYGDDPSTNSFEKEKQDYVYCLESSLQTYNPDYVLMVEDDAVPEEQIFPVLEHLLRARFSEPHLRDALYLKLYHPERLQHYINPEPMRILEWVGVGMLLGPLLTWIYMRFASRPGFSWPVMLFFSLYSMGLVELVGRHYFLELRRLSPSLYSVVPASQCCTPAMLFPAPAARRTLTYLSQVYCHKGFGKDMALYSLLRAKGERAYVVEPNLVKHIGLFSSLRYNFHPSLL
What is the function of this protein?
Golgi-resident glycosylphosphatidylinositol (GPI)-N-acetylgalactosamine transferase involved in the lipid remodeling steps of GPI-anchor maturation.  Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins (PubMed:29374258).  Required for the initial step of GPI-GalNAc biosynthesis, transfers GalNAc to GPI in the Golgi after fatty acid remodeling by PGAP2 (PubMed:29374258).
What are the official names of this protein?
Post-GPI attachment to proteins factor 4, Post-GPI attachment to proteins GalNAc transferase 4, Transmembrane protein 246.
What is the protein family that this protein belongs to?
Belongs to the PGAP4 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RS12_STAEQ
Sequence: MPTINQLVRKPRKSKTKQSDSPALNRGFNSKKKQFTNLNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNNIEVNAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: G3P_ASPNG
Sequence: MAPKVGINGFGRIGRIVFRNAINHGEVDVVAVNDPFIETHYAAYMLKYDSTHGQFKGTIETYEEGLIVNGKKIRFFAERDPAAIPWGTTGADYIVESTGVFTTQEKAAAHLKGGAKKVVISAPSADAPMFVMGVNNTSYTKDINVLSNASCTTNCLAPLAKVINDKFGIVEGLMTTVHSYTATQKVVDAPSSKDWRGGRTAAQNIIPSSTGAAKAVGKVIPTLNGKLTGMAMRVPTSNVSVVDLTCRLEKATSYDEIKKALKDASENELKGILGYTEDDIVSSDLNGDDHSSIFDAKAGIALNSNFVKLVSWYDNEWGYSRRVVDLIAYISKVDAQ
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_BURA4
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVLAIERLLGIDVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDAMPQYKASKIRNEKALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQMGLTGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSIRIAKQCIEWLRKNPGPVMTDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ISPH_MANSM
Sequence: MKIILANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVNGLRERGAVFVEELNEVPDGAIVIFSAHGVSQAVRQEAKNRNLKVFDATCPLVTKVHMQVARASRKGTKAILIGHEGHPEVQGTMGQYDNPEGGIFLVENVEDIAKLGLKDNEELTFMTQTTLSIDDTSDVIVALKAKYPAIQGPRKNDICYATTNRQQAVRELAEQSDLVIVVGSKNSSNSNRLAELASRMGVPAKLIDDSNDIEPDWLKGINTIGVTAGASAPEVLVQSVIARLKELGVDSVEELEGCEENTVFEVPKELRIKEVG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MURC_LEPCP
Sequence: MKHAVKHIHFVGVGGAGMSGIAEILHNLGYTVSGSDQADGAVTRRLAELGIRIFVGHDAAHIAGAQAVVTSTAVKGDNPEVIAARAARIPVVPRAVMLAELMRLKSGIAIAGTHGKTTTTSLVTSVLAEAGLDPTFVIGGKLNSAGANSALGKGDYIVVEADESDASFLNLLPVLSVITNIDADHMDTYGHDFARLKQAFVEFLHKMPFYGAAILCGDDPGVRSIIPMISRPVITYGLGEDVQVRAVDVVALPGGQMRFTCQRRNGTVLPDLEITLNLPGVHSVRNALATIAVATELELPDAPIVSALAKFSGVGRRFQRWGDWPCAAGGEFTLIDDYGHHPVEMAAVIAAARGAFPGRRLVLAFQPHRYTRTRDCFEDFVKVMGSADAILLTEVYAAGEAPIVAADGRSLTRALRVAGKVDPLFVDDVNELPATIAEQALAGDVVIAMGAGTIGGVPARVVELVKERA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEBP_DROME
Sequence: MLNMESPQMYADAVQTLAQLDLKKEPPLQQATIGQITLTAMSTAQQQQQQQQQQQQQQQQQQQQQQQQPQQQTTDANNNTSQDAALLVKQHAMHQMQQVAALGSNNNLLQKQMLQQYSTQTDLDELTTQEITLDLQHLIDDQFRDTETLGIFSDMVTSPGGLSATLPPSGMVSAAAKVLQQQTLRNQHGYGGRGGGGGAGGALAYMPQPVHATYNNSSDENSSVGSDSSTIKEEPIDPEYRRHLQEAASQQAAFMGNGAGLYNGYGSGANGLTGGGNPLNGGNTTPSSNGSNGSTGSSNGSQFTNLTTANVLAHHNLPHLAAAAGAHNLLKQHSKLHAQQQHQQHQQQQQHRKHSNKHVDKGTDEYRRRRERNNIAVRKSREKAKVRSREVEERVKSLLKEKDALIRQLGEMTNELQLHKQIYMQLMNHANPEVSRVCRSFLNTNEHSL
What is the function of this protein?
Required for the expression of gene products mediating border cell migration (PubMed:1459454, PubMed:10949024, PubMed:23305818).  Among the DNA sequences that this protein binds with high affinity is a conserved site within the promoter of its gene (PubMed:1459454).
What are the official names of this protein?
CCAAT/enhancer-binding protein, C/EBP, Slow border cell protein.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. C/EBP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP2_SYNSC
Sequence: MIPIVIEESGRGERAFDIYSRLLRERIIFLGEAVTSDSANRIVAQMLFLEAEDPEKDIYLYINSPGGSVYDGLGIFDTMQHIKPDVHTVCVGLAASMGAFLLCAGTKGKRSSLQHSRIMIHQPLGGAQGQASDIRIQADEILFLKERLNKELSDRTGQTLDRIQQDTDRDFFMSPTEAMNYGLIDSVIDKRPVQAVA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URFN_NEUCR
Sequence: MGNKKKSVGGKINFLELLTFIQFLTHKLTLTPPKPHLFVTSNLQASIWNWPSKSRITEISKAIWMNMIKKFKIFIFFALPTMLIVKGIYICYDQEIWTLVFFTQNLVKNFPFFGLRLFNMIWVESNLGVEASNLGVEAPKASSIFLDLHLWTLMYLFGSLARIFGELYYSDFELPAGVGGESCEKKTPSPRGPLTLYKKGSDSGASGGSDSPPSAKGNSGASSGPNQDRLAPETDSEDETTQTDQGPRSRGYRKTRTRSMVRRRWIRDKPDWVEGLWTRSSTEGVENLDATKASQTKSAAENLDAIKASQTPKSAAENLDAAAIKASQTPKSAAENLDAAKGSKSKSKSAVKKAAKAAKKLAAENLDAIKASQTPKSAAENLDAAAIKASQTPKSAAENLDAAKGSQTKSAPKNLAPITGSQAPKVKAALAEFLGIETSQLQTTAVVRELATKLEDDLPGSLDFADQENGNKIISMLKLREFALQENNRYRSTIYKSLGQFMDPESHKNLKEILDKLEESKNLLMTEGQKHKNTFDRNSQQNTAYNFKGDMKKYLELQNKVQHSQMKNFKLAESIIQKNIQREYKCKELKDFLHQEFPTSCRDFNDQEMKLKKYFLNAFNQAKTKN
What are the official names of this protein?
Uncharacterized mitochondrial protein urf-N.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RDRP_I49A1
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNDLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMITQRTIGKKKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKRLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEEYQGRLCNPLNPFISHKEIESVNNAVVMPAHGPAKSMEYDAFATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: LDH_MYCPN
Sequence: MKSLKVALIGSGAVGTSFLYAAMSRGLASEYMVIDINEKSQVGNVFDLQDAVPSSPQYSKVIAGDYKQLKDYDFIFIGAGRPQKQGGETRLQLLEGNVEIMKNIAKAVKESGFKGITLIASNPVDIMAYTYLKVTGFEPNKVIGSGTLLDSARLKFAIAEKYGMSSRDVQAYVLGEHGDSSVSIISSAKIAGLPLKHFSKASDIEKEFAEIDHFIRRRAYEIIERKGATFYGIGEATAEVAELILRDTKEVRVVASLINGQYGAKDVMFGTPCVLGRNGVEKILEIELSATEKAGLDKSIQVLKDNIKLAKL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.