PharMolix/UniProtQA huggingface dataset:
Protein: RRF_BACAH
Sequence: MGQQVLKSSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_AERS4
Sequence: MRLNTLSPAAGSKPEKQRRGRGIGSGLGKTGGRGVKGQTSRSGGGKVRAGFEGGQMPLKIRLPKFGFFSRKSLVSAEVRLNEIAMVEGDVVDLSTLKQAGVVTKNIVFAKVVLSGNIDRAVTVRGVSVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TMM42_BOVIN
Sequence: MAGRPLPGGGGVCAAAYPNTSAGFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLAFGREVNVGFCVLGIIMMATTNSLMWTFFSRGLSLSMSSAIASVTVTFSNILNSAFLGFVLYGECQEVLWWGGVFLILCGLTLIHRELPPPRKPLPHKQR
What are the official names of this protein?
Transmembrane protein 42.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UTR1_ARATH
Sequence: MEVHGSGFRRILLLALCISGIWSAYIYQGVLQETLSTKRFGPDEKRFEHLAFLNLAQSVVCLIWSYIMIKLWSNAGNGGAPWWTYWSAGITNTIGPAMGIEALKYISYPAQVLAKSSKMIPVMLMGTLVYGIRYTFPEYMCTFLVAGGVSIFALLKTSSKTISKLAHPNAPLGYALCSLNLAFDGFTNATQDSIASRYPKTEAWDIMLGMNLWGTIYNMIYMFGLPQGIGFKAIQFCKLHPEAAWDILKYCICGAVGQNFIFMTISNFGSLANTTITTTRKFVSIVVSSVMSGNPLSLKQWGCVSMVFGGLAYQIYLKWKKLQRVEKKKQKS
What is the function of this protein?
Essential sugar transporter required for the transport of UDP-galactose and UDP-glucose from the cytoplasm into the Golgi and the endoplasmic reticulum, to ensure quality control of protein folding.  Essential for pollen development and involved in embryo sac progress.
What are the official names of this protein?
UDP-galactose/UDP-glucose transporter 1, At-UDP-Glc/GalT, AtUTr1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CBID_BURL3
Sequence: MRDETPEQPAPLRFGYTTGSCATATSLAAARLLLAGSADDAVEIVLPKGQRVMMRLEFCRATADGAEAATIKDAGDDPDVTHGALIFARVALASAPGVRFHAGPGVGTVTRAGLTLPVGEPAINPVPRQMMTTHLEALAAEHGYAGGFDVTIGVEGGEALALKTMNPRLGIVGGLSILGTTGIVRPFSCSAYIASIHQGIDVARANGIAHIAACTGNASEDAMRAHYQLPDMALIEMGDFAGAVLKHLRRAPVARLSMCGGFGKLSKLAAGHLDLHSRHSSIDLPLLAQWAAEAGASDALQAAMRAANTSQEALKLAHADGVPLGDLVCAQALRVARDIVPPSVAVEIFAIDRQGRFVGEAR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: APL3_MELSA
Sequence: DAAQVPDFATAVQNLXHTLSEAA
What is the function of this protein?
Assists in the loading of diacylglycerol, generated from triacylglycerol stores in the fat body through the action of adipokinetic hormone, into lipophorin, the hemolymph lipoprotein.  It increases the lipid carrying capacity of lipophorin by covering the expanding hydrophobic surface resulting from diacylglycerol uptake.  It thus plays a critical role in the transport of lipids during flight in several species of insects (By similarity).
What are the official names of this protein?
Apolipophorin-3, Apolipophorin-III, ApoLp-III.
What is the protein family that this protein belongs to?
Belongs to the insect apolipophorin-3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: URED2_SACEN
Sequence: MGRRAPDRLDRGVTTTSPRTQAPPQAGRGVHATARIRATSHDGVTVLPLLRSDGPFHLRQLRNHGSQARVCVVSAMSAPLGGDRLAIDVSVEAGAQLEITTAAATLALRGATTDHATYDVTLTVGEQATLYWLPQPLISTRGSNLRQTYTVDLAPTARLILREELILGRAHEPPGDLSSHLTVHRDGRPLLAQHTTFGSTAPGWDGPAVLGEHRATGQILIVDPAFANAPPATRLLGDEPANGEGIVAPLAGPAVLATALAPTATPLRHLLDDAVRPRTPCST
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 2.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I01A0
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSGDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQIRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DPO3_STRT2
Sequence: MSDKFKLLLKQIHFPQHEEAYNEIKSGSIESVKLFKSKRQWFFVFSFRNLLSYETFTLFDNLLHSSFDSLGAKVSYMINVEDISCDQSLLEAYFSYALDILKSSHFSIYSLFSNLGIEISNNSISVKAPAHILRENLHERFIALIADVLSNVGLSNVSISVLEDKEASSSLEEAYETNKISLQEEAESQARQALQSIVQSSPVPPPQKHQAQNFAEKQSQRVASFDKAEITPMIEVNSEENRIVFEGYIFDVEQRETKTGRIIINFKVTDYTSSFAMQRWVKDSEELVKFGMIKKGNWVRVRGRIENNPFTHSLTMNVQDIKEISHTPRKDLMPEGQKRVEFHAHTNMSTMDAIPTVEELIDTAAFWGHPAVAITDHANVQSFPHGYHKAKKAGIKAIFGLEANLVEDKVPIVYNSENLELKEATYVVFDVETTGLSAVHNDLIQIAASKMHKGNIVEQFDEFIDPGYPLSAFTTELTGITDNHVKGAKPLVQVLQEFQEFCKGAVLVAHNATFDVGFMNANYERHQLPTISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALDHHHMANYDAEATGRLLFIFIKDVFEKHGLTNLEQLNTELVSDDSYKKSRVKHATLYVQNQTGLKNIFKLVSLSNVSYFEGVARIPRKVLDEYREGIIVGSACADGEVFDTLLSHGIDKAVEVAKYYDFIEVMPPAIYAPLIAKDLIKDEEAIEQLIRDLIEVANRLDKPVLATGNVHYINPEDAIYREIIVRALGQGAMINRPIGKGENAQPAPLPEAHFRTTNEMLDEFAFLGKDLAYEIVVANTQAMANQIEEVEVVKKDLYTPYIDRAEEQVAEMTYAKAFELYGNPLPDIIDLRIEKELSSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYLCPKCQHSEFITDGSYGSGFDLPDKECSECGTEYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEQYAFRAGTVGTVADRTAYGFVKGYERDYNKFYRDAEVDRLAMGVAGVKRNTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAAWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPKDIRADDPDVMKLFSGTEVLGVTPEQIGTSTGVLGIPEFGTNFVRGMVEETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLDPKMAFTIMERVRKGMWLKISEEERNGYIQAMRENNVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMEDIKEKRQRNEATNLENDLFTTLEIVNEMLERGFTFGQLDLYKSQATEFLIEGDTLIPPFIALEGLGENVAKQLVAAREEGEFLSKTELRKRGGLSSTLVERLDEMGILGNMPEDNQLSLFDDFF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4E_PYRHO
Sequence: MARKGPKRHLKRLAAPSSWYIERKAYKWAVRPRPGPHNMRTSIPLLYIVRDYLGYAKTAREARKILNEGKFLVDGKVRKDYKFPVGIMDVVSIPETGEHYRVLPNRIGKLVLHPISEEEANIKPLRIRNKRMVKGAKVQLNFHDGTNHLIPLTEKDNYFTSYTVLMKVPEREIMEVLPFEKGAYVFVTQGKNVARKGRIVEIKKFPMGWPDVVTIEDEEGELFDTLKEYAFVVGKDKPKISLP
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: CYSI_PECAS
Sequence: MSEKYVFSEKHPGPLVVEGKLTDAERMKTESNFLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVMTPQQWLRIDKFAGENTIYGSIRITNRQTFQYHGILKSNVKPVHQMLNSIGLDALATANDMNRNVLCTSNPIESELHQQAYEWAKTISEHLLPRTRAYAEIWMDQEKVATTDEEPILGSTYLPRKFKTTVVVPPQNDVDLHANDLNFVAIADNGRLVGFNVLVGGGLSIAHGDKETYPRTASELGYISIEHTLAIAEAVVTTQRDWGNRTNRKNAKTKYTLERVGVDNFKQEVEARAGVKFEAVRPYEFTERGDRIGWVKGIDNKWHLTLFIENGRILDYPGRPLKTGLAEIAKIHKGDFRLTANQNLIVAGVPARSKAKIDALAREHGLIDDSVSEQRKNSMACVSFPTCPLAMAEAERFLPEFVTKVEGIMQQHGVGDEHIVLRVTGCPNGCGRSMLAEIGLVGKAMGRYNLHLGGNREGTRIPRMYRENINETEILAEIDRLVGLWAQDRLQNEGFGDFVIRTNIIRPVLDPARDFYD
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RS19_CENSY
Sequence: MVKKFEYRGKPAEELESMPLDSLFRLFNSRQRRSLTRGITDGKRKLIREIKDARAGKEGNPIKTHLRDLIVLPSMTGVTVNVFSGKEFRPVEITTEMIGHYLGEYVITNKRVSHGAPGVGASRSSLYVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RRAA_SALSV
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRSSFGGQIITVKCFEDNGLLYDLLEQNGRGRVLLVDGGGSVRRALVDAELARLATQNEWEGLVIYGAVRQVDDLEELDIGIQAIAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM134_HUMAN
Sequence: MSAARPQFSIDDAFELSLEDGGPGPESSGVARFGPLHFERRARFEVADEDKQSRLRYQNLENDEDGAQASPEPDGGVGTRDSSRTSIRSSQWSFSTISSSTQRSYNTCCSWTQHPLIQKNRRVVLASFLLLLLGLVLILVGVGLEATPSPGVSSAIFFVPGFLLLVPGVYHVIFIYCAVKGHRGFQFFYLPYFEK
What are the official names of this protein?
Transmembrane protein 134.
What is the protein family that this protein belongs to?
Belongs to the TMEM134/TMEM230 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region.
Protein: TIF9_ORYSJ
Sequence: MSTRAPVELDFLGLRAAAADADDRHAKSGGSSASSSSSIRGMETSAIARIGPHLLRRVIAAAGPPPPPSTAPVPEEMPGAAAAAAPMTLFYNGSVAVFDVSHDKAEAIMRMATEATKAKGLARGNAIVGNFAKEPLTRTKSLQRFLSKRKERLTSLGPYQVGGPAAVGATTSTTTKSFLAKEEEHTAS
What is the function of this protein?
Repressor of jasmonate responses.
What are the official names of this protein?
Protein TIFY 9, OsTIFY9, Jasmonate ZIM domain-containing protein 5, OsJAZ5, OsJAZ11.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
Protein: TRUA_LACCB
Sequence: MTHYKVTLAYDGTNFAGYQVQPKQRTVQGVLQKALTKMTKGQPVHVDGSGRTDSGVHALGQVISFDYPGNIPAESMLKAMNSLMPLDIEILKAEIVDADFHARYSAKGKRYLYRVARGYYTNPFNRLYTGHYPYKLDVQRIEVALKDLVGTHDFTSFAASGGVIVDKVRTIYEATVREDPVTNEIIFEFYGNGFLYNMVRILVATALEIGNGRRDVHDFQRLFAVKDRQQARGTAPASGLYLKEVYY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL30_PARD8
Sequence: MATIKVKQVKSRIKCPKDQKRTLDALGLRKMNQIVEHEANPAILGMVEKVKHLVSVEK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SRB8_USTMA
Sequence: MLRSGAASASSGGGRGPSSSLSSVKRSKHDDTRLPEAYQQERPPWRPPLHPTAARRHVPDLFPTKSGQPEDDMSQISVRKGFAPRTYVHNEYFCAHDAIHTRLLSPDALDTLSDWMDEVMQRRRELDRASIATNQYKPPSRVTLNDAKLANYVKDLADPTVPLMRLSRSVPHGFRGEKLFEMLWVGGALPSTATAATTTVNYFHSRIAGPPSASSASASASASASTSAPRKSVDIPRAVWFIRALGAAELSSLRNKSAATIIPEITSNLCAWMAKQVAELNLVHTAESNSTATASPAPVSPSTHLPRTPSAAPSSLSRSVAAAHFARTPSNLNPASSPSLAPAKEVCYVLQNDADEERWIAKWSYSLSLARHLHAQNLLDRSVLVRWIVDAFSASNLVQLPFLLELVQEVLLLVLRRRCFVKPFLTALLVQIPNVDARLDPSSSGGLRTKLVLLFRIVCENSPESLISPRLWFEHSASLTQLLNELNAETPLPLSHQAFEFVEQTVRPRVDRLLLRPHSGNTTQNASLETQETLSSPLQHHLDIQALDSFDMTTIDRVFLQNTSATHRYAKHDRDDTVWATRIDTILTWACTDRRSGVVRQYLAATLIEKIRFGVPWEESSEETDQVSLPAFDLEHNTTKTRKINVEPMLIKWLGDVETSLNQKLDESSTQTRVSLLATVDVGAIVVLLGELARRGVFSYTKYLQRLIARGMTAPSASSATEQHQNPDGSVQTPSSVSASRDSLHLRLLRSLPLYDQPASVYQQRRQAIYGDRTKETYEDAAQRRALRQLQSFLPFAFAQEVQAEASRIAVSPSPSTPDPVHALSRLWSASRFVRCRLFRSELLPAVTARVERLNGDQLSQISAVLVMADDFEGLAQLLATLLLRPLSDNLARAAFNMVIEYSLVWRSMDIMATLNQLVRQQLNHSSSIRNDRQAVMASTTLLRLRTLIENVPSRISASALDPGADHDALQQHVQALRPNVDALLDRFAKLTRSSVESDGSIASSSTPVEGSDMLTPFRSLFVQPDAMSDEMIERTIVDSVFARSDTSLVPSAVRLIDQLYLEASLEIDERHARWLSNLVLSIEQGTHSDASMKALLSLLTRLIAHGTLNLQLAMDTFLLPYLLSSVRRLTDPATRNTEVPMHIGSIVSSLGEIFASSLGETVPATSYEDMRAFGAQTKLLFAQVNLPSLLRAATCLISAFDETSTVPASEKAQIESFCNALLQSQPMQIAFRQEPRLCILAIKDTCKSMWGCNPSRVIDLAMACLDPTSLLLRDVGTIDAASVKNRLDGWDTAVVATELVEIFERLQLVESSFQTRADSKTKALASGIFDDLFVQLPDIGAQLVRDCQSSGLVSRFTDIGIKILSDKVKAASTDADKTPRRMDNSHKGMTNFGPDDGADAPAQAKTAADAAKHGPCVGEQQVESTLRSVVRMCEQQHSFIFNATDADSCAQLLLHVVTSLEDALGSMAAASHQDKVARLVTVLHGSMTFQLMHLVLRFGCLWNGTMRALALRLVKALLELTRQAGEKTECGGSFALLLDSLSFVLDELPPTLLSTCLPELETQLQTIELATQERSDKLQQLSFRLDNATTANAWLVASSAGAALKKGWFTSGGLNPWECAEYLEAPPAANPAAAGAAGAAGAAAGGNARAGVVETGRSGVNSRAAVESPGAVTVNDAETCNSLPGARTGWTGKLWLNTAIPLSMLGVRVTRDLVPNYASPASPGGVSVGSNDASSQPWTTGGGASAIGVGTCSAMDMDAKEALAALPMFVESERTYGERSAGEPAYSRDLRRGLLVEPNLPCRTRDERGETSQEPARATMDPAGAHTSVTSSATHDPSHVIDLTWDADEEMPLSTHPHHPAVATTSRKRRLSKRD
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFG_PSEU2
Sequence: MARTTPIGRYRNIGIVAHVDAGKTTTTERVLFYTGKSHKMGEVHDGAATTDWMVQEQERGITITSAAITAFWQGSEKQHKDQFRFNVIDTPGHVDFTIEVERSLRVLDGAVVVFCGTSGVEPQSETVWRQANKYGVPRIVYVNKMDRAGANFLRVIAQIKQRLGHTPVPIQLAIGAEDNFQGQIDLMSMEAVYWNDADKGMVPVRKPIPAELQELADEWRSNMVEAAAEASEELMNKYVDGEELTNDEIKAALRQRTIAGEIVLAVCGSSFKNKGVPLVLDAVIDYLPAPTDIPAIKGSDPDNEEKLMERHADDNEPFSALAFKIATDPFVGTLTFVRVYSGVLASGDGVINSVKGKKERVGRMVQMHANAREEIKEVRAGDIAALIGMKDVTTGETLCNADKPIILVRMDFPEPVISVAVEPKTKDDQEKMGIALGKLAQEDPSFRVKTDEETGQTIISGMGELHLDILVDRMRREFNVEANIGKPQVSYRERITKNCEIEGKFVRQSGGRGQFGHCWIRFAPADEGQEGLQFVNEVVGGVVPKEYIPAIQKGIEEQMKNGVVAGYPLIGLKATVFDGSYHDVDSNEMAFKVAASMATKQLAQKGGGELLEPIMAVEVVTPEDYMGDVMGDLNRRRGMILGMEDTVSGKVIRAEVPLGEMFGYATDVRSMSQGRASYSMEFKKYNTAPSHIVETVTKKQG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFCL_HALWD
Sequence: MTDWTERYRPTTLSAVRGNNAARDEFIEWAESWDDHHESVVLHGAPGVGKTSAAHALASDMGWETVELNASDQRTSDVIERLAGRAAKNATLAGAVSGTTSTRQLIIMDEADNIHYQYDRGGKQAVTTLLKDANQPIVLIANEYYDMSRGLRNAAQDIEFRDISARSIVPVLRNILRKENIEFEEAALKQIAEVNSGDLRAAIKDLQTTVEGSDRITVDDVKTGGRDRAMGLFSFLDSVLKEDAAEEALQNSYDVDETPDDLLKWVEDKVPLVYDDAELARAYEFLSNADIWTNRVYATDYNYRWWRYATDNLAGGVAAARETQRGGWTRYGGAPYRSTRDSTRDTVVREVAKTGGFSMATARTAVIPFLSAITHLCKPRSLTVGMAAWYELDEAGVSYITGSGETTKKVASIVEDAAERRSEAVEAHAGSAFAETETEEKTNFTGNQDSDVDVQSHKSAESGDDTVRTANTPAEDHAQSGASETASATESASDSDASTDTDADDDDGQAGLSEFM
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: IMP07_NAUMA
Sequence: TFVSSQVSGPR
What are the official names of this protein?
Uncharacterized protein IMPP7.
Protein: MUTS_STRPC
Sequence: MTKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTSVRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGYTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEYLIRTAIDPDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQESGINNLKIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFNDNHVITIQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIMSVPPQVESSSAVRQGQLSLFGDDEKAHEIRQALEAIDVMNMTPFQAMTTLYELKKLL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PSME3_PONAB
Sequence: MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDDCEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY
What is the function of this protein?
Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome.  11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits.  Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage.  May also be involved in cell cycle regulation.  Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (By similarity).
What are the official names of this protein?
Proteasome activator complex subunit 3, Activator of multicatalytic protease subunit 3, Proteasome activator 28 subunit gamma, PA28g, PA28gamma.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to the cytoplasm during mitosis following nuclear envelope breakdown at this distinct stage of the cell cycle which allows its interaction with MAP3K3 kinase.
Protein: RS11_PSYWF
Sequence: MAKDTRGRKKTARRSVSEGVAHIHASFNNTIVTITDRQGNALAWATSGGQGFRGSRKSTPFAAQVAAEVAGKAAQETYGVKNVDVLVKGPGPGRESAVRALGALGYKINSISDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GUAA_CLOBB
Sequence: MKRDLVLVIDFGGQYNQLIARRVRECNVYCEVHPYNLSVDEIKQMNPKGIIFTGGPNSVYGENSPLCDKAIFELGVPIFGICYGSQLMSHILGGKVATAPVSEYGKTKVDVNIESKLFEGVSSSTICWMSHTDYIEKAPEEFKVIGNTPVCPVAAMECEDKNLYAVQFHPEVMHTEEGTKMLSNFVYNICGCTGDWKMDSFVEKTIEEVRQKVGNGKVLCALSGGVDSSVAAVLLSRAVGKQLTCVFVDHGLLRKNEGDEVEEIFGPNGQYDLNFIRVNAQERFYEKLAGIEEPEQKRKIIGEEFIRVFEEEAKKIGTVDYLVQGTIYPDVIESGLGKSAVIKSHHNVGGLPDYVDFKEIIEPLRLLFKDEVRKAGLELGIPEKLVFRQPFPGPGLGIRIIGEVTAEKVKIVQDADAIYREEIANAGIDKEIGQYFAALTNMRSVGVMGDERTYDYAIALRAVTTSDFMTAESADLPWEVLGKVTTRIVNEVKGVNRVMYDCTGKPPATIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RABL3_DANRE
Sequence: MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYREGTPEEKAFYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALSKDSSPTGIIVSNGDYDREQFAENAVPLLLIGTKFDQIPENKRNDVLTRTAFLSEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFTRDPSQMQSFTDRRRFNFKSLHSD
What is the function of this protein?
Required for KRAS signaling regulation and modulation of cell proliferation (PubMed:31406347).  Regulator of KRAS prenylation, and probably prenylation of other small GTPases (By similarity).  Required for lymphocyte development and function (By similarity).  Not required for myeloid cell development (By similarity).
What are the official names of this protein?
Rab-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: DEOC_BURL3
Sequence: MPLSNAQLAQTIDHTLLAPDASDAQIRELCRQAAEHRFYSVCVNSANVPLAARELADTGVLVCAVVGFPLGAGLSAAKAFEATVAIAAGAGEIDMVINIGALKSGRADDVKADIDAVHRACGAVPLKVILETGLLTDDEKVRVCEMCRDLGVAFVKTSTGFGHGGATLADVALMRRTVGPVLGVKASGGVRDRAAALAMIEAGATRLGTSSGVAIVTDQDGSASAY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXY11_DANRE
Sequence: MSQLTELVLLTVFLALFSRAEANPFVYNYEALRIGGLVFTCVLVAGAVTALCWGQCKPKRKHDDDASKI
What is the function of this protein?
May modulate the activity of a sodium/potassium-transporting ATPase.
What are the official names of this protein?
FXYD domain-containing ion transport regulator 11.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.