PharMolix/UniProtQA huggingface dataset:
Protein: PP2AB_DICDI
Sequence: MNTSTFNLDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAPQSLSNKPTLDTNKELPDYFL
What is the function of this protein?
Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay (PubMed:20493808).  The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway (PubMed:20493808).
What are the official names of this protein?
Protein phosphatase 2A catalytic subunit B, PP2A-C2.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
What are the subcellular locations of this protein?
Cell membrane. Note=The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells (PubMed:20493808). Membrane localization of the Sca1 complex is regulated by scaA phosphorylation by PKB and PKB-related PKBR1 (PubMed:20493808).
Protein: SLMA_SHEPW
Sequence: MAASPKINRREHILQCLATMLETSPGQRITTAKLAAEVGVSEAALYRHFPSKARMFEGLIEFIEESLLSRINLIMDEEKDTMKRCQQLLQLLLVFAERNPGISRVLNGDALLGENERLRSRISQLFSKIETHLKQILREKSLREGQAFSIDEAVLANLLMAIAEGRIAQFVRSEFKLKPTKHFNEQWTFVQQQLLQS
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RPOZ_BACC0
Sequence: MLNPSIDSLLTKIDSKYTLVTVAAKRAREMQLANNCVVEKPVSHKCVGKALEEIDMEALSYVPSEDKVTE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RIMK_SERP5
Sequence: MKIAILSRDGTLYSCKRLVEAAEQRGHSIEVIDPLSCYMNINPAAPTIHYRGRQLERYDAVIPRIGSAMTFYGTAVLRQFELLGSYPLNESVAITRARDKLRSLQLLARQGIDLPITGFAHSPDDTGDLIELVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIREAQGSDVRCLVVGSKVVAAIERQAKPGEFRSNLHRGGTARKVSITAKERAIAVKAATTLGLDVAGVDILRAARGPLVMEVNASPGLEGVESTTGLDIAGRMIEYIEQRGRPGFRLKSGG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: KAD_CLAMS
Sequence: MTRLLIVGPPGAGKGTQAKRIAADRGIPDVSTGDIFRQNIKDRTELGQQVQALVDAGNYVPDELTNRLVTVRLQEEDAQAGFLLDGYPRTLAQVAYLEELLQGWGQELDAVIQLVADEDEVVARLTRRAAEQGRADDGEDEIRHRQEVYVRETSPLIDVYREHGLLVEVDGLGEVDEVAERIRTALAARGVRPSSDAGRA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOR11_ARATH
Sequence: MQIYRRPFETKTWQYRICPAETMVKIHPDLTTSGAGEETSSPYLTTEQESFTIWMKSLVFNTNGCTVFDSKGNIIYRVDNYNSKSCREVYLMDLSGHVLFTLRRQKFGLFKTWEGYRSSSATVESTTKLEYFRVKNNVFQVPNKDSSSSYRVNAGSCRNDEQYCYKMVTRGSSLAIEDNCGKLLAEVKRKQSINGLKLGDDVLTMMVESQVDHSFIIGLVLAHSLINCIL
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 11.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: SECA_PSEAB
Sequence: MFAPLLKKLFGSKNERDVKRMAKAVQAINALEPQMVALSDEQLKAKTAEFQQRYAKGETLDQLLPEAFAVVREAGKRVMGMRHFDVQLIGGMTLHDGKIAEMRTGEGKTLVGTLPVYLNALSGKGVHVVTVNDYLARRDANWMRPLYEFLGLSVGVVTPFQPPEDKRAAYAADITYGTNNEFGFDYLRDNMAFSLDDKFQRELNFAVVDEVDSILIDEARTPLIISGQAEDSSELYIKINKLIPRLNRQVEEVEGKPTEEGHYSIDEKTRQVELNEQGHQFIEDLLSQNGLLGEGESLYSAHNLSLLTHVYAALRAHTLFHRNVEYIVQGDQILLIDEHTGRTMPGRRLSEGLHQAIEAKEGLPIQAESQTLASTTFQNYFRLYNKLAGMTGTADTEAFEFRQIYGLDVVVIPTHRPIARKDFNDLVYLTQEEKYAAIITDIKQCQALGRPILVGTASIESSEYVSKLLQEAGIEHKVLNAKYHEKEAEIIAQAGAPGSVTIATNMAGRGTDILLGGNWEVEVAALENPTEEQIAQIKAEWQKRHQQVIEAGGLHVIASERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDNLMRIFASDRVKNFMKALGMQSGEAIEHRMVTNAIEKAQRKVEGRNFDIRKQLLEFDDVANEQRKVIYHMRNTLLSAEDVGETIKEFREETLSATINQHIPPQSLPEQWDIEGLEAALYSDFAVRLPIQQWLDEDDKLYEETLRSKILEQIVAAYYEKEELAGAEALRAFEKQMLLRVLDDLWKDHLSTMDHLRHGIHLRGYAQKNPKQEYKRESFTLFQELLDSIKRDTIRVLSHVQVRREDPAEEEARLRREAEELAKRMQFQHAEAPSMEQAVAGEEEELPEGPAPVVPLEPVRNEQKIGRNEPCPCGSGKKYKHCHGQLD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PYRF_STRPN
Sequence: MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAGPEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAAREGLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEVQVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPVAAYHAIKDEWTQDWN
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: MIAA_PARDP
Sequence: MTLRHPILAELDPARPILIAGPTASGKSALALEIAEAQGGTVVNADALQVWSCWRLLTARPTAEDEARAPHALYGHVAPDRAYSVGAWLAEVAALMDKGCDSGRGRLIVTGGTGLYLNALSRGLAVIPPTPPEIRAQADQLVRQPGGLARMIEDLDSSTRARIDLRNPARVQRAWEVLTTTGRGIAAWQAETPPPLIDPAAAHLLVLNPDRDWLAERIARRFHLMLEQGALDEVRAMLPHWNPDALWAKAIGAPELVAHLQGRIDLDEAARRAVIATRQYAKAQRSFFRGRMRDWRWIGIGG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: FABP4_CEREL
Sequence: MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPTLIISVNGDVVTIKSESTFKNTEISFKLGQEFDEVTPDDRKVKSTINLDGGALVQVQNWDGKSTTIKRKLVDDKLVLECVMNGVTATRVYERA
What is the function of this protein?
Lipid transport protein in adipocytes.  Binds both long chain fatty acids and retinoic acid.  Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
What are the official names of this protein?
Fatty acid-binding protein, adipocyte, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
Protein: RSPRY_MACFA
Sequence: MIVLGWAVFLASRSLGQGLLLTLEEHIAHFLGTRGATTTMGNSCICRDDSGTDDSVDTQQQQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSGHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTISGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
What are the official names of this protein?
RING finger and SPRY domain-containing protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: FADR_YERPE
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHDSVPQLIDNLLAVRTNIATIFVRTAIRHHPEKAQEILARAKTVDDNAEAFTALDYGIFRGLAFASGNPIYGLILNGLKGLYTRVGRYYFSNPEARKLALTFYNKLSTLCDTESYDQVLECLRTYGKESGAIWHSMQGTMPSDLAEARR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.  Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE.  Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the gene encoding the transcriptional regulator of the aceBAK operon encoding the glyoxylate shunt enzymes.  Binding of FadR is specifically inhibited by long chain fatty acyl-CoA compounds (By similarity).
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPL8_ARATH
Sequence: MRSPAKTMPSMSPSSVSTEKSPPPSDTSMAIVAFDNSTTHFSSSPSPPHSLDHSSESEKEDAKSKPESRRNKNPGKVEETPSPIVVVHNHNRSVKEVVPTRKSARVGSGRSSGQRSGAVSAILRRSRREEVVKFSALGFRLSEVVLALISFSIMAADKTKGWSGDSFDRYKEYRFCLSVNVVAFVYSSFQACDLAYHLVKEKHLISHHLRPLFEFIIDQVLAYLLMSASTAAVTRVDDWVSNWGKDEFTEMASASIAMSFLAFLAFAFSSLISGYNLFNQGSL
What are the official names of this protein?
CASP-like protein 4A3, AtCASPL4A3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPA_FRATH
Sequence: MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDHLADGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISKLGSGYTYLLSRVGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKIIQNNISNKQKMLNELTYFVKEMKAATLN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: SECB_PSET1
Sequence: MNEETQNAAAQQETGAQFTIQRIYTKDVSFETPNSPAIFQKEWTPEVKLDLDTRSNKLDEGVFEVVLALTVTASIGEETAFLCEIQQAGIFTIADVEETQLAHMLGAFCPNVLFPYAREAVSNLVNRGTFPQLNLAPVNFDALFAQYMQQRTAQAEQASVDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTC_XANC8
Sequence: MGLEVAADSVGSALAAQDGGAIRVELCGGLDGGGLTPSFGTLAVVRERLQIPLYVLIRPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALDPQGQVDLPAMRALIEAAGTLGVTFHRAIDVSADPARVLEDAITLGCERVLTSGARASALEGVETIAALVRQAGERISIMPGAGVSAANVQALRAGTGAREFHASARGPVAAQVHAPHPYITDLGGDYQRTDVARVRSIVQLLQTA
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMC5_DESVH
Sequence: MYAFLTGPMLWASLLVFFGGLLARVIWYIRGLDWRLDRVAYKPHLAIGLQGAVQSALKWLVPFGTYSWRQQPFFTVAFFLFHIGAVLVPLFLAGHNVILEERFGFSLPALPMGVADTLTVLAIIGLVMIALRRIALTEVRILTTGYDWFILAVSAAPFVTGFLARLHVGDYDTWLLAHIITGELFLIVAPFTKLSHIVLFFMSRGQLGMDYAIKRGGATRGPAFPW
What is the function of this protein?
HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates.
What are the official names of this protein?
Protein DVU_0532, HMC operon ORF 5.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADE_BUCAT
Sequence: MTLQKKIIELLGVKPAIIPEIEIKNCVDFLKKYLVNHVHIKSLIVGVSGGQDSTLTAKLCQMTAETLRKEKNDITYQFIALRLPYGIQYDEKDCQDAIRFIQPDQIFNVNIKKAVLSSEKSLKKSGVIISDYVRGNEKARERMKVQYSVAAMKQGLVVGTGHAAENITGFFTKYGDSGTDINPIAKLNKRQIRLLLKNLNCPKHLYLKKPMADLEDEHPQQDDESVLGVTYDVIDSYLEQKKIDIRSQKIIEALYLNTLHKRNLPITQ
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RL6_PSEMY
Sequence: MSRVAKNPVVLPAGVEVKLAGQQLSVKGAKGALELNVHSSVEVIQEGSELRFAARNGDQQNKAMAGTTRALVNNMVIGVSQGFERKLQLVGVGYKAQAKGQVLNLALGFSHPIDYELPAGVVAETPNQTEILIKGIDKQLVGQVAAEIRDFRRPEPYKGKGVRYADEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YPTV5_VOLCA
Sequence: MSTKKRRVLKIIILGDSGVGKTSLMNQYVQKKFTKEYKATIGADFLTKEIEVDDKKVTMQIWDTAGQERFQSLGSAFYRGADCCMLVFDVNNAKSFDDLDNWRDEFIIQAGPSDPDNFPFVVLGNKIDEVGVNRQVTEKKAKAWCASKGSIPYFETSAKEDINVEAAFTCITRNALRNEKEEELFVPDAVDMNTSATQRKRGGCC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
GTP-binding protein yptV5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: LIPP_MYOCO
Sequence: LLLGAVAGSEVCYDRLGCFSDDSPWAGIVERPLKVLPWSPSTINTRFLLYTNESPNNYQIVTADSSTIRSSNFRTDRKTRFIIHGYIDKGEENWLANMCEALLQVESVNCICVDWKGGSRALYTQATQNIRVVGAEVAYFVDALQSQLGYSPSNVHIIGHSLGSHVAGEAGRRTNGNIGRITGLDPAEPCFQGTPELVRLDPSDAQFVDVIHTDGAPIIPNLGFGMSQTVGHLDFFPNGGVEMPGCQKNIISQIVDINGIWEGTRDFAACNHLRSYKYYIDSILNPTGFAGFSCSSYNTFSSNNCFPCASGGCPQMGHYADRFSGKTNELFQQFYLNTGDASNFSRWRYQIAVTLSGRKVTGHVLVSLYGSGGTSKQYEIYKGSLQPGTSYVNQIDSDVDVGDIEKVKFIWYNNIINPTLPKVGASSIQVTRNDGRVFNFCSQDTVREDILLTLTPC
What is the function of this protein?
Plays an important role in fat metabolism.  It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
What are the official names of this protein?
Pancreatic triacylglycerol lipase, PL, PTL, Pancreatic lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_STAA9
Sequence: MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX35D_CTEON
Sequence: GKCGEINGSCDECYGGSVTCDCY
What is the function of this protein?
Insecticidal neurotoxin that reversibly inhibits the N-methyl-D-aspartate (NMDA)-subtype of ionotropic glutamate receptor (GRIN) and inhibits inactivation of insect sodium channels (Nav).  In vivo, is highly toxic to insects.
What are the official names of this protein?
U1-ctenitoxin-Co1a, U1-CNTX-Co1a, Neurotoxin Oc F17-11.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 05 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RAM2_PETHY
Sequence: MDGTLLVGRSSFPYFALVAFEVGGIFRLLFLVLASPLAGLLYYFISESAGIRVLIFATFAGMKVSDIESVARAVLPKFYSSDLHPETWHVFSSCGKRCVLTANPRIMVEGFLKEYLGADMVIGTEISMYKGRATGFVNKPGILVGDNKAMALKKAFCSTSTPDIGLGDRKTDFPFMNLCKESYIVRPDPGVKPMSQDKLPKPIVFHDGRLVQKPSPLMALMIILWIPVGFLLACLRIAAGALLPMPLVYYAFWALGVRVKVKGNPPPPAKKSTDQTGVLFICSHRTLLDPIFLSTSLGRPIPAVTYSVSRLSEIISPIKTVRLSRDRVTDANMIKKMLEEGDLVICPEGTTCREPFLLRFSALFAELTDELVPVAMSNKMSMFHGTTARGWKGMDPFYFFMNPSPTYEVTFLNKLPYDLTCKAGKSSHDVANYIQRTIAATLSYECTNFTRKDKYKALAGNDGTVTTKPGLAAKKVMGC
What is the function of this protein?
Involved in the production of cutin monomers (By similarity).  Esterifies acyl-group from acyl-ACP to the sn-2 position of glycerol-3-phosphate, a step in cutin biosynthesis (By similarity).  Required for colonization of the root by mycorrhizal fungi, and appropriate hyphopodia and arbuscule formation (PubMed:25971550).  Cutin monomers act as plant signals that promote colonization by arbuscular mycorrhizal fungi (By similarity).  This signaling function has been recruited by pathogenic oomycetes to facilitate appressoria formation and their own invasion (By similarity).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase RAM2, Protein REQUIRED FOR ARBUSCULAR MYCORRHIZATION 2.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPAM_HELAN
Sequence: MEFSPRAAELTTLLESRISNFYTNFQVDEIGRVVSVGDGIARVYGLNEIQAGEMVEFASGVKGIALNLENENVGIVVFGSDTAIKEGDLVKRTGSIVDVPAGKAMLGRVVDALGVPIDGRGALSDHERRRVEVKAPGIIERKSVHEPMQTGLKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTILNQKQMNSRSTSESETLYCVYVAIGQKRSTVAQLVQILSEANAMEYSILVAATASDPAPLQFLAPYSGCAMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKRSDQTGAGSLTALPVIETQAGDVSAYIPTNVIPITDGQICSETELFYRGIRPAINVGLSVSRVGSAAQLKTMKQVCGSSKLELAQYREVAALAQFGSDLDAATQALLNRGARLTEVPKQPQYAPLPIEKQILVIYAAVNGFCDRMPLDRISQYERAILKSIKTELLQSLLEKGGLTNERKMEPDTFLKECALPYTI
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.  Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).
What are the official names of this protein?
ATP synthase subunit alpha, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: CDKA1_MESAU
Sequence: MSYKPNLTAHMPAAALNAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARSLVRECLAETERNARS
What is the function of this protein?
Inhibitor of cyclin-dependent kinase CDK2 (By similarity).  Also acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 2-associated protein 1, CDK2-associated protein 1, Deleted in oral cancer 1, DOC-1, Putative oral cancer suppressor.
What is the protein family that this protein belongs to?
Belongs to the CDK2AP family.
Protein: IGF2_PIG
Sequence: MGIPMRKPLLVLLVFLALASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVNRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFRYDTWKQSAQRLRRGLPALLRARRGRTLAKELEAVREAKRHRPLTARPTRDPAAHGGASPEASGHRK
What is the function of this protein?
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion.  Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
What are the official names of this protein?
Insulin-like growth factor II, IGF-II.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIP_NEUCR
Sequence: MEHRTRSWALGLSILGFFALLFSAGFVQQAHANDTEAMGTVIGIDLGTTYSCVGVMQKGKVEILVNDQGNRITPSYVAFTDEERLVGDAAKNQAAANPHRTIFDIKRLIGRKFSDKDVQNDIKHFPYKVVSKDDKPVVKVEVKGEEKTFTPEEISAMILGKMKETAEGYLGKKVTHAVVTVPAYFNDNQRQATKDAGMIAGLNVLRIVNEPTAAAIAYGLDKTGEERQIIVYDLGGGTFDVSLLSIEQGVFEVLSTAGDTHLGGEDFDQRIINHFAKLFNKKHGVDVTKDAKAMGKLKREAEKAKRTLSSQMSTRIEIEAFYDGKDFSETLTRAKFEELNNDLFKKTLKPVEQVLKDAKVSKSEIDDIVLVGGSTRIPKVQALIEEFFNGKKASKGINPDEAVAFGAAVQAGVLSGEEGTEDIVLMDVNPLTLGIETTGGVMTKLIPRNTPIPTRKSQIFSTAADNQPVVLIQVYEGERSMTKDNNLLGKFELTGIPPAPRGVPQIEVSFELDANGILKVSAHDKGTGKAESITITNDKGRLTQEEIDRMVAEAEKYAEEDKATRERIEARNGLENYAFSLKNQVNDEDGLGGKIDEEDKETILDAVKEAQDWLEENAATASAEDFDEQKEKLSNVAYPITSKLYSQGGAGDDEPAGHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.  Is required for secretory polypeptide translocation.  May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, Immunoglobulin heavy chain-binding protein homolog, BiP.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.