PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_ACICJ
Sequence: MTETASRRTLHITTWGCQMNVYDSGRMADVLRPLGYRQVATQDADMVILNTCHIRERASEKLFSELGRLRALKESRGGAMMIAVAGCVAQAEGAEILARAPHVDLVVGSQAYHRLPELIAEIEAKRRAVIDTDFPAAQKFDLLPEDQASQGPIAFLAIQEGCDKFCTFCVVPYTRGAEASRPAAAILAEARRLVAGGAREIALLGQNVNAWHGEAPDGATWNLARLLAELADIDGLARLRYTTSHPRDMDAALIAAHRDNPKLMPFLHLPVQSGSDAILARMNRRHGADLFRRIAGELRAARPDIALSSDFIVGFPGETDADFAATMRLVRETGFALAYSFKYSRRPGTPAADAADQIDEAVKDARLQELQAVLRDQQHAFNRAQVGRSFEVLFTGPGRHPGQSAGRSPYLQPVVVDNADIPPGTLRTVKIVQSNPNSLMASLTQEQIAA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENB_STAAM
Sequence: MTNRQWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
What is the function of this protein?
Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA synthase, DHNA-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
Protein: NPY6R_MOUSE
Sequence: MEVLTNQPTPNKTSGKSNNSAFFYFESCQPPFLAILLLLIAYTVILIMGIFGNLSLIIIIFKKQREAQNVTNILIANLSLSDILVCVMCIPFTVIYTLMDHWVFGNTMCKLTSYVQSVSVSVSIFSLVLIAIERYQLIVNPRGWKPRVAHAYWGIILIWLISLTLSIPLFLSYHLTNEPFHNLSLPTDIYTHQVACVEIWPSKLNQLLFSTSLFMLQYFVPLGFILICYLKIVLCLRKRTRQVDRRKENKSRLNENKRVNVMLISIVVTFGACWLPLNIFNVIFDWYHEMLMSCHHDLVFVVCHLIAMVSTCINPLFYGFLNKNFQKDLMMLIHHCWCGEPQESYENIAMSTMHTDESKGSLKLAHIPTGI
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.  The rank order of affinity of this receptor for pancreatic polypeptides is NPY = PYY >= NPY (2-36) = [Leu-31, Pro-34] NPY > NPY (13-36) > PP.  The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity.
What are the official names of this protein?
Neuropeptide Y receptor type 6, NPY6-R, Pancreatic polypeptide receptor 2, PP2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL21_ECODH
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CITD_SERP5
Sequence: MKIIREAMAGTLESSDVMVRIAPAEGPEHDLLIASSVEKQFGEAIRQTLLQVLQHYQVEPVQVMVDDKGALDCVLRARLETALMRACDNGQLPWGAPNENAE
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_LISMO
Sequence: MNLQTMIRTLQDYWSEQGCIMLQSYDVEKGAGTMSPYTFLKAIGPEPWKAGYVEPSRRPADGRYGENPNRLFQHHQFQVVMKPSPDNIQELYLGSLEKLGINPLEHDIRFVEDNWENPSLGCAGLGWEVWLDGMEITQFTYFQQVGGLECFPVTSEITYGVERLASYIQDKENVFDLEWTEGISYRDIFFQAEFENSTYAFETSNTDMLLTLFDTYEREATRQMQDGLVFPAYDYVLKCSHTFNLLDARGVVSVTERAQYIGRIRNLARRIAKTFYESREKLGFPLLKEEGGKRHE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y645_MYCPN
Sequence: MKLKLKFLLISLLGSSLLLSACSSAATQVISSLSSAQKYFESSQGELNKKNVIKILKEGYESDANKAVHALLAGWKYTLMDQQLLSKEVDSRFIKAFGSGRDKGDVTPSVSEKGLYLNETYTGFSSQIAKVLGVQSQTVKQFNYKWSSNSDFKVQIQISMKGKVGSDSESQQLIKSFLSSDNNGSNQNGGVKETDFNGDSANFDGFFTFTYTPPTQSRKFGATSFDPLTTKINFPADLQIDVSTTHQKLNTLMEANEQVKQIKSRKFTGKTFDLLPFFYYALL
What are the official names of this protein?
Uncharacterized lipoprotein MG439 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the MG439/MG440 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PAL_RHILO
Sequence: MGRIAALTRNPVMIALVAMLAIAGCASKKTPNNAADLGLNGAGAATPGSAQDFTVNIGDRIFFDTDSSSIRADAQTTLARQAQWLNQYKQYAIVVEGHADERGTREYNLALGARRAAAARDFLVSKGVASSRLKTISYGKERPVAVCDDISCWSQNRRAVTTLSGAGS
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Peptidoglycan-associated lipoprotein, PAL, Outer membrane lipoprotein Omp16 homolog.
What is the protein family that this protein belongs to?
Belongs to the Pal lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: VG69_BPMD2
Sequence: MTQIKLPLRSVSQINQYTKCPMAYKLARIDKVWQRPAAWLPQGTAFHAVAEAVEVWESYGMPLTLDEAKDMFRWHYANDVGAFTEETPNFEWWTWSGPYNGQRDIERRYTVGLEQVEKFFAWRGTPGQEIWVTPDGTPAIELYFEIELDGILVRGYIDAVVVVDGELRVRDYKTGNQPGDDFQLGVYALAVAMTYGVEAPKTGDYFMVGKKGKAPKPTKPYDLTKWTREAITEEFHRVEEGIAASMFDPLPEPDKCKFCDVSYSCPVFK
What are the official names of this protein?
Gene 69 protein, Gp69.
Protein: HIS1_DEIGD
Sequence: MTPAPARDPDHLTLALPKGRILEDAVTLLARAGLPLTLPEKSRALRHEFPGVTVLELRNQDVPVYVDLGVADAGIVGKDVLIESGRAVYEPVDLRFAACHLSLIREVGASGPIGRVATKYPRSARAYLASRGIPAEVVKLSGNIELAALTGLADAVVDLVQTGSTLRANHLEEIDVLYHSSARLIVNRAALKLRRARLRPLIERLRELVERDAQEGTGNL
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOSS_BACSU
Sequence: MQIKIKYLDETQTRINKMEQGDWIDLRAAEDVAIKKDEFKLVPLGVAMELPEGYEAHVVPRSSTYKNFGVIQTNSMGVIDESYKGDNDFWFFPAYALRDTKIKKGDRICQFRIMKKMPAVDLIEVDRLGNGDRGGHGSTGTK
What is the function of this protein?
Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP, so that uracil cannot be incorporated into DNA (PubMed:9679200).  The Ser-62 side chain changes its position upon ligand-binding to make contacts with the nucleotide phosphates (PubMed:21358047).
What are the official names of this protein?
SPbeta prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TSN13_BOVIN
Sequence: MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNQEQQAQLLEVGWNNTASARDDIQRNLNCCGFRSFNPNDTCLASCVKSSHPCSPCAPIIGRYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL
What are the official names of this protein?
Tetraspanin-13, Tspan-13.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CID16_SCHPO
Sequence: MLFAKLLLKPVQILFAYAKAKSKEISIKEANLLIFQDETDNLRKISTPNKLAVSLAGGLKALLSSNQLCHAFHYHNKKIRLVDTSLNNLPVPILLPKLINYLLARKSQKSAAEWEEIERALLSCCKRSKDPSILFPTDVPCSLDDDVSFLTFKGHKNHLENRSFFHDSESDNFKVVLSNCAINSKEDNNLVTEDRVNLGAKLLLVPVQNLIKLLKVSKISVDLAVIDHSFQDQKLTLEVGNGGLEVVKLFGGWIRILESECLGHVFSFKKTMKRKEVALVNRKADIDTTDLFIALRQLVDSKFKSYGIKAQKHAINRISKLGKMITSNHAEEKLTTIPITEAKKESVSNTALIARKNIIRERKYLSRMFDIFEHIDSYFNHEINMLLVDLLLEPLQVAFVYKNLARRWISLEEIENLWLKVFDSSHPLGKSITSTLQAIGTRKILTQLSINMIPRYNQDNCSAGDIYILCFSENCWLYSVLQKTIDHWVNENVELFYKKFEILKSLLIEDIANSTFSKEVSLNSSLRWYCVAILVTPLQLIINHLKDKTEMLSLDAVMTLILGKNTREVNSSIEELKITDCLSFLLEHNIFNTFLVYNEGIVKLNKDFDDFTPLNLLKCVNYSLMEFQKNSTFDMLEKLYEIGREIDMSKFSTLKYNLQLPNVDLLKESEAVSETKNTKNNTFILKSDLKEEERLTNFTIEEINKHKAIGVALRKLLEEADTSSNFSSSNNHVLDSSKHTVSSASTSSRKFIENYKSLESIGLTSFVKDNKLKASKELQKLIEENVFPKNLILFIFRKCVIGIKSFEKLQSYVFTYYCERYPKLILKRVLRFLEEIGFITSQYPRKLTDTGALFLKHPSEWGVLQHTFISSNFFENVPCYISLEQSLQNFQNDIRPDTVRTTAMKAIIKKLLKSLRKLEGPVKIACFGSYRTGLMTKNSDLDLVIYSSKEALLPYYDRVKSIIKNEFSNVMPIRGARIPIIKFTGQYNIHCDLSFDNLLPIHNSDLILNYSLIDERVKTLLMLVKYWASNRLIDKTHHAFPSSYTWCIMVIFYLQQIPEPILPNLQKLSTQYSKIVRDNDYGNVNCWFNRDTECYRGSMQKGRKNIALLLRGFFCYYGLTTQYSFDWEAYMIDISSSQLKRKSTEFKDCPFVVLDPFLKKKNLTKALTQKSVKVVRYELERACRILSDPKCNLDHLLDPLIQ
What are the official names of this protein?
Caffeine-induced protein 16.
Protein: SFSA_ECOLU
Sequence: MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGCATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAIICVNTLWANRLTKEAILNESISELSGYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKHLRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAELSAEGMALKKSLPVTL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: XERC_STAAR
Sequence: MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQLNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKSLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNF8_MOUSE
Sequence: MDHQDKAATVAMASRPQATQLQEPVTFRDVAVDFTQEEWGQLDPTQRTLYRDVMLETFGHLLSVGPDLPKPAVISQLEQGAELWVADRGGTGACHPGWILEPEDHTLLKDQGLPKMEPSPITEKDGFAKAVPCRSMIGIDQESDGQRQALKKDQSNLNDPKEIPLQSQSHKSLGLVEACVLGLNTYLLPDISGREYGCTYDSQVKNSEHNPSLVRQRTDSPATQSFDDNGSQKAFDQIMPITELTKSQVQDKPYKCTDCGKSFNHNAHLTVHKRIHTGERPYMCKECGKAFSQNSSLVQHERIHTGDKPYKCDECGKSFCHSTHLTVHRRIHTGEKPYECQDCGRAFNQNSSLGRHKRTHTGEKPYTCSVCGKSFSRTTCLFLHLRTHTEERPYECNHCGKGFRHSSSLAQHQRKHAGEKPYECRQRLIFEQAPALIKYEWTEPLGCDSPLSQGERTQRSDRPFKCNQCGKCFTQSSHLIRHQLTHSREEEPLRGRSRRQEQPCRRGSRLIQNTNSNSRELPVAQPKAGQASRTLALFDLREIMQEQNPVHVIGVEEPSVGNSMLFDTRESR
What is the function of this protein?
Transcriptional repressor.  May modulate BMP and TGF-beta signal transduction, through its interaction with SMAD proteins.
What are the official names of this protein?
Zinc finger protein 8, Zinc finger protein 128.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPD_CROS5
Sequence: MYLLIPAAGMGKRMGSNRNKLLLTLLGKPLLSWTLLAAEASQKIEWVGIIGQPYDFPEFKTILTTISFTKPVELIQGGETRQASVYNGLQALPKAADNVLIHDGARCLVTPDLFDRCAEELLTCQGLIAAISVKDTIKIVDSNQFIKDTPNRSNLWAAQTPQGFKVSLLKQCHEKGYQLGWQVTDDAALFEKCQLPVKIVEGEETNLKVTTPVDLAIAEFILKQRFTH
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: MIAB_CLOD6
Sequence: MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQTFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLKHLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDKMLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDIINEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHPKDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPGIAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDIKHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGGNDDLIGKLVMVKITEPRTFSLNGILVNN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_STRP2
Sequence: MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQPDGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKIAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVPELGSATIHPVSLEEMKDYLVK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAT6_BOVIN
Sequence: MPKVKALQCALALEIRSVTCPGVVLKDKEDIYLSICVFGQYKKTQCVPANFPLVFNARMVFEKVFPEAVDPGDVVAQLEYDTALFELIQLVPPVGETLSTYDENTRDFMFPGPNQISGHHDSNRQVTMRRISGLRGIAPKLEFSTTSVITECLISSRKCRTQDKFVYHTAPVEKPHSRLQNRTSRSQKKKSKSPERNKYCINAKNYEQPTTSKSHSPSPYTKRRMCELSEDTRRRLAHLNLGPYEFKKETDKPPFVIRHVDPPSPRADALFGSPGRDCERDGWSRLHNDHSHLGCYRPKDYKVIRTPHGRDFDESLERCEDYLSSRSCSKPQHSARTLLVHSAPSTMPKHSPSPVLNRASLRERFHSDWCSPSNCDEIHDRVKNVLKSHQAHQRHLYDERDPEKEDELELKRGLLYRDSAYDSDPEYSSFQRPRGTLHLDDGEYWSNRAASYKGKSHRPIFENSMDKIYRNLYKKACSSVSHTQESF
What is the function of this protein?
Required for formation of the sperm connecting piece during spermiogenesis.  Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis.  May be involved in myosin-based microfilament transport through interaction with myosin subunits.
What are the official names of this protein?
Spermatogenesis-associated protein 6.
What is the protein family that this protein belongs to?
Belongs to the SPATA6 family.
What are the subcellular locations of this protein?
Secreted. Cell projection, cilium, flagellum. Note=Specifically localizes to the segmented columns and the capitulum of the sperm connecting piece.
Protein: INT12_PONAB
Sequence: MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKISSTKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRLEKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPAVKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASISSSVTSGLTGWAAFAAKTSSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPLKPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTPGPSGSTASKTTSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 12, Int12, PHD finger protein 22.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLSX_LISMF
Sequence: MKIAVDAMGGDHAPKEIVLGVMKAVAQYKDVEILLFGDETKINEYLTDKTRVKIIHTDEKIESDDEPVRAVKRKKKASMVLAAQAVKDGEADACISAGNTGALMSTGLFVIGRIKGIDRPALAPTLPTVTGKGFVMLDLGANAEAKPEHLLQFGLMGSVYAEKVRKIDRPRVALLNIGTEETKGNDLTKKSFELMKNQDAYEFIGNIEARDLLMDVADVVVTDGFTGNMVLKSIEGTGAAFLSMLKMSLLNGFKNKVAASFLKKDLMALKAKMDYSEYGGACLFGVQAPVVKAHGSSNANGIFTTIRQVREMVEKQVVETIKAEVDKVKVGGTESND
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: COAD_PSET1
Sequence: MKITAIYPGTFDPLTNGHTDLIQRASKMFDTVIVAIAHNPSKQPCFSLDERVALANTLLTHIDNVKVIGFSGLLADLARDHNANVLIRGIRAVSDFDYEFQLANMNRRLNPDLESVFLTPSERNSFISSTLVKEVARHNGDVSEFVDPIVMAALNKKLGCSYSK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_SALPB
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: MCR1_CHAGB
Sequence: MSLFVASRSAFRAAAPLKRQFQIRRYATEPPSADAKKGNNTLLYGAAAAAVAGAGYYFLGGTPAAKKAEEKVKDASSAAAGKLSTSEVKQALTGGEQGWVSLKLEEVEIVNHNSKRLRFRLPEDDMVSGVHVASAILTKFKPVDAEKPVIRPYTPTNDEDARGYLDLLVKKYPNGPMSTHLHDMVPGQRLDVKGPLPKYPWTANKHGHIALVAGGTGITPMFQLCRAIFNNPDDQTKVTLVFGNVREDDILLKKELAALENNNPRRFRAFYVLDDPPKHWTGGKGFITKDLLKTVLPEPKDENIKVFVCGPPGMMDAISGNKKSPKDQGELKGILKELGYSPEQVYKF
What is the function of this protein?
May mediate the reduction of outer membrane cytochrome b5.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, Mitochondrial cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RL22_FINM2
Sequence: MQAKAIAKYVRISPLKVNFICKEIRGKQVDEALAILKFTPKKGARILEKVLNSAIANAEHNFGLNREDLFVSQAYANNAPVMKRWRPKAKGMAYPILKRSSHVGVVVEEREL
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: FOXC2_MOUSE
Sequence: MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYGAGMGRSYAPYHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVPKDKEERAHLKEPPSTTAKGAPTGTPVADGPKEAEKKVVVKSEAASPALPVITKVETLSPEGALQASPRSASSTPAGSPDGSLPEHHAAAPNGLPGFSVETIMTLRTSPPGGDLSPAAARAGLVVPPLALPYAAAPPAAYTQPCAQGLEAAGSAGYQCSMRAMSLYTGAERPAHVCVPPALDEALSDHPSGPGSPLGALNLAAGQEGALGASGHHHQHHGHLHPQAPPPAPQPPPAPQPATQATSWYLNHGGDLSHLPGHTFATQQQTFPNVREMFNSHRLGLDNSSLGESQVSNASCQLPYRATPSLYRHAAPYSYDCTKY
What is the function of this protein?
Transcriptional activator.  Might be involved in the formation of special mesenchymal tissues.
What are the official names of this protein?
Forkhead box protein C2, Brain factor 3, BF-3, Forkhead-related protein FKHL14, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14.
What are the subcellular locations of this protein?
Nucleus.
Protein: GENL1_ORYSJ
Sequence: MGVGGSFWDLLKPYARHEGAGYLRGRRVAVDLSFWVVSHSAAIRARSPHARLPHLRTLFFRTLSLFSKMGAFPVFVVDGQPSPLKSQVRAARFFRGSGMDLAALPSTEAEASADALVQPRNAKFTRYVEDCVELLEYLGMPVLRAKGEGEALCAQLNNQGHVDACITSDSDAFLFGAKTVIKVLRSNCKEPFECYNMADIESGLGLKRKQMVAMALLVGSDHDLHGVPGFGPETALRFVQLFDEDNVLAKLYEIGKGVYPFIGVSAPNIDDLPSPSTKSLPRARSPHCSHCGHPGNKKNHIKDGCNFCLVDSLENCVEKPAGFICECPSCDKARDLKVQRRNENWQIKVCKRIAAETNFPNEEIINLYLNDDNLDNENGVPLLTWNKPDMEILVDFLSFKQNWEPAYIRQRMLPMLSTIYLREMASSQSKSFLLYDQYKFHSIQRIKIRYGHPYYLVKWKRVTRSMISNDPPSKQTELEGKNDKVEVLDGDDEVVDEEEEEPTMISETTELLDEPDVPQVLDDDKDCFLLTDEDIELVNAAFPDEAQRFQEEQRLKEAKSIARKSKLNVAGFETPKGPRPSGVQLSIKEFYRSKKGLSGDSGKDGSRKSSDVDLSKNLPKSVRRRLLFD
What is the function of this protein?
Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA.  Possesses both single-stranded and double-stranded DNA-binding activities.  Involved in early microspore development, but does not alter meiosis or tapetal cells development (PubMed:15792960, PubMed:22247560).  Possesses Holliday junction (HJ) resolvase activity in vitro.  Cleaves HJ at symmetrically related sites of the branch point (PubMed:22247560).
What are the official names of this protein?
Flap endonuclease GEN-like 1, OsGEN-L, Protein OsGEN-like, OsRAD.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIG_NEIM0
Sequence: MLTLYSETFPSRLLLGTAAYPTPEILKQSVRTARPAMITVSLRRAGCGGEAHGQGFWSLLQETGVPVLPNTAGCQSVQEAVTTAQMAREVFETDWIKLELIGDDDTLQPDVFQLVEAAEILIKDGFKVLPYCTEDLIACRRLLDVGCQALMPWAAPIGTGLGAVHAYALNVLRERLPYTPLIIDAGLGLPSQAAQVMEWGFDGVLLNTAVSRSGDPVNMARAFALAVESGRLAFEAGPVEARDKAQASTPTVGQPFWHSAEY
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.