PharMolix/UniProtQA huggingface dataset:
Protein: MED30_AEDAE
Sequence: MSGQYPSGYQSPSGHRGNFNSPMMQQQLNQMGVPNQMGMMGFNQGNVMQNQQQMQSGGVQSGPDIGMGQNIQQQQQPNPSQGTGQGQQQQPGQGQAQGQQQQNPQQSPQLGMAAGGQAVSSAAQSATGTVGGAPPGQPNAGPVASTQAASNVQQKEFNLLTLCRIGQETVQDIVSRFQEVFGLLRGIQPPNGTNAGLSSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDNCQQGMEYTHVESLIPLKGEPERAEPIHTEEYKKALQENRELIEIVMLKNKQLREIIDKIRLTIWEINTMLSMRRC
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 30, Mediator complex subunit 30.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 30 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GRP2_MOUSE
Sequence: MTSTLDLDKGCTVEELLRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLASKLLHFYQQSRKDNSNSLQMKTCHLVRYWISAFPAEFDLNPELAEQIKELKALLDQEGNRRHSSLIDIESVPTYKWKRQVTQRNPVEQKKRKMSLLFDHLEPMELAEHLTYLEYRSFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTATQRALVITHFVHVAERLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPDTIKLWEGLTELVTATGNYSNYRRRLAACVGFRFPILGVHLKDLVALQLALPDWLDPGRTRLNGAKMRQLFCILEELAMVTSLRPPVQANPDLLSLLTVSLDQYQTEDELYQLSLQREPRSKSSPTSPTSCTPPPRPPVLEEWTSVAKPKLDQALVAEHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLSAFGDLDQNQDGCISREEMISYFLRSSSVLGGRMGFVHNFQESNSLRPVACRHCKALILGIYKQGLKCRACGVNCHKQCKERLSVECRRRAQSVSLEGSAPSPSPTHTHHRAFSFSLPRPGRRSSRPPEIREEEVQSVEDGVFDIHL
What is the function of this protein?
Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP.  May also activate other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS.  Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation.  May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
What are the official names of this protein?
RAS guanyl-releasing protein 2, Calcium and DAG-regulated guanine nucleotide exchange factor I, CalDAG-GEFI, F25B3.3 kinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the RASGRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Synapse, synaptosome. Cell projection, ruffle membrane; Peripheral membrane protein. Note=Found both in the cytosol and associated with membranes. Enriched at juxtamembrane areas and membrane ruffles. Localizes to the cell bodies and axons of striatal neurons.
Protein: RF2_AERS4
Sequence: MFEVNPVLNKLKELSERTELLRGYFDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERVSLENVVGTIDVLTQGAEDVEMLVSLAVEGEDEDTFNEAVAEADVLETKLVDLEFRRMFSGQHDGSDCYIDIQSGSGGTEAQDWANMVLRMYLRWGDAHGYKPELIELSDGDVAGIKSATVKFTGEYAFGWLRTETGVHRLVRKSPFDSGGRRHTSFCSVFVYPEIDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGVVVQCQNDRSQHKNKDQCMKQLKAKLYELEIQKQNAEKQALEETKSDIGWGSQIRSYVLDDARIKDLRTGVETRNTQAVLDGDLDKFIEASLKSGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRUM3_MOUSE
Sequence: MATPGLGVLLAFGLPMLPSGWSLTAPDPFTNSTTQPPGDESNGGLSSGAIVAITVVFSILGVLLIAVGLFLLMRKLREKRQTEGTYRPSSEEQVGARAPPPPNLKLPPEERLI
What is the function of this protein?
Involved in the establishment of cell polarity in mammalian epithelial cells (By similarity).  Regulates the morphogenesis of tight junctions (PubMed:21145499).  Involved in promoting phosphorylation and cytoplasmic retention of transcriptional coactivators YAP1 and WWTR1/TAZ which leads to suppression of TGFB1-dependent transcription of target genes such as CCN2/CTGF, SERPINE1/PAI1, SNAI1/SNAIL1 and SMAD7 (PubMed:21145499).
What are the official names of this protein?
Protein crumbs homolog 3.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells.
Protein: NTF3_ERYCN
Sequence: IQSTSMDQGILTEDSMNSFIRTLIQAGIWKNKVPKQTARTKDGTQTTVKKTEAEADAMVSKDTRLSFQPIVSVDAELLRQQRRFSSPRVLLSENTPLEPPPLYLTEEPTVLNRTSRRKREGKSHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGPS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2917_MYCTU
Sequence: MLHFTAATSRFRLGRERANSVRSDGGWGVLQPVSATFNPPLRGWQRRALVQYLGTQPRDFLAVATPGSGKTSFALRIAAELLRYHTVEQVTVVVPTEHLKVQWAHAAAAHGLSLDPKFANSNPQTSPEYHGVMVTYAQVASHPTLHRVRTEARKTLVVFDEIHHGGDAKTWGDAIREAFGDATRRLALTGTPFRSDDSPIPFVSYQPDADGVLRSQADHTYGYAEALADGVVRPVVFLAYSGQARWRDSAGEEYEARLGEPLSAEQTARAWRTALDPEGEWMPAVITAADRRLRQLRAHVPDAGGMIIASDRTTARAYARLLTTMTAEEPTVVLSDDPGSSARITEFAQGTSRWLVAVRMVSEGVDVPRLSVGVYATNASTPLFFAQAIGRFVRSRRPGETASIFVPSVPNLLQLASALEVQRNHVLGRPHRESAHDPLDGDPATRTQTERGGAERGFTALGADAELDQVIFDGSSFGTATPTGSDEEADYLGIPGLLDAEQMRALLHRRQDEQLRKRAQLQKGATQPATSGASASVHGQLRDLRRELHTLVSIAHHRTGKPHGWIHDERRRRCGGPPIAAATRAQIKARIDALRQLNSERS
What are the official names of this protein?
Uncharacterized protein Rv2917.
What is the protein family that this protein belongs to?
To M.leprae ML1624.
Protein: MAP11_SYNY3
Sequence: MGDTITLLSRREIEKMRQAGQLAAALLDHLAPMVQPGITTLELNDEAEKWTKAHGAISAPLGYNGFPKSICTSINEVICHGIPHRKRVLQAGDIINVDVTPIVDGYHGDCSRTFFVGTPSPVAEKLVKVTEECLRLGIEAVKPGGKIGDIGAAIQSHAEAQGFSVVRDFVGHGISKIFHTAPQIPHYGKAGKGKRLRPGMVFTIEPMINEGTWEAVLLDDGWTAITKDGKLSAQFEHTIAVTEDGVEILTLGE
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase A, MAP A, MetAP A, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: RL10_VIBPA
Sequence: MALNLQDKKAIVAEVNEAASGALSAVVADSRGVEVGAMTSLRKQAREAGVYMKVVRNTLARRAVQGTDYECLTDTFTGPTLIAFSNEHPGAAARLFKDFAKENKDFEIKAAAFEGALTDAEVLATLPTYDEAIARLMMCMKEASAGKLVRTIAAIRDQKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: KUP_BRUA2
Sequence: MSGELNGNDTSAQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYAFREALHAAATNGILARSDILGVVSLIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALVRGALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEGLEIVAPNLTPFVVPAAVVILVTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSPAVAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGEAAALPFFQMIPSFALWPMVLLATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSEKLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAVTGNMLVTTVLLYIAMTRIWNWRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKTRKAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVVTASKPWVASADRARVSQYNERFMLVTLTFGYMQQPNIPRALGLCRRLGWKFDIMTTSFFLSRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTGRVVEIGTQVNI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATRX_RABVA
Sequence: MNVLRKIVKKCRDEDTQKPSPVSAPPDDDDLWLPPPEYVPLKELTSKKNMRNFCVNGDVKACSPNGYSFRILRHILRSFNEIYSGNHRMIGLVKVVVGLALSGAPVPEGMNWVYKLRRTLIFQWADSRGPLEGEELEYSQEITWDDDTEFVGLQIRVSARQCHIQGRIWCINTNSRACQLWSDMSLQTQRSEEDKDSSLLLE
What is the function of this protein?
Plays a major role in assembly, budding and uncoating of virion after membrane fusion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication.  Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons.
What are the official names of this protein?
Matrix protein, Phosphoprotein M2.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus matrix protein family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein. Host cytoplasm.
Protein: SURE_NITEU
Sequence: MRILLSNDDGYFAPGIANLAKVLLEIADVTVVAPERDRSGASNSLTLDRPLSLHKSHNGFYYVNGTPTDCVHLAVTGMLDELPDMVISGINDGANMGDDTVYSGTVAAATEGFLLGLPSIAVSLVSMSRGNFPTAARIVVDLVKRFTENRFHIPILLNVNVPDVPYDELQGVEVTRLGRRHKAESVIKYQTPRGETVYWVGAAGAAQDAGEGTDFFALQNNRVSITPLQIDLTRYDQIGYVKNWLTL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_BARBK
Sequence: MRKKKNVLIRKIIAENRKARFNFELLEHLEAGIVLNGTEVKSLRSNHANIAESYASFENEELWLVNAHIPEYTQANRFNHEPRRLRKLLVSKREIGRFFNAVSREGMTIVPLKLYFNERGCVKLEIALARGKKIHDKRETEKKRDWGREKARLLRRYG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y677_LACDA
Sequence: MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKSGGPDPLGNPRLRLAVDKARAANMPKDNIQRAIKKAEGNSDEHYDEVTYEGYAPGGVAILVEALTDNKNRTASSVRVAFTRNGGSLGATGSVAYMFDRKGYIVIDRSTTDADEDQMLMDVMEAGGDDLQTSDDAYEIYTDAKSFTAVRDALEKAGYQLAVSELTMVPQNTTPVPADKKEQFEKLVDALEDDDDVSNVYTAAADEEE
What are the official names of this protein?
Probable transcriptional regulatory protein Ldb0677.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFT_LEVBA
Sequence: MSNFIFGRYLPLDSVVHRLDPRAKLMLSFCYIIVVFLANNIWSYAILIAFTVGAILSSKISLGFFLKGIRPLLWLIVFTVVLQLLFSPAGGHTYFHWAFINVTQDGLINAGYIFVRFLLIIMMSTLLTLSTQPLDIATGLASLMKPLRWVKVPVDTLAMMLSIALRFVPTLMDEATKIMNAQRARGVDFGEGGLFKQAKSLIPLMVPLFMSAFNRAEDLSTAMEARGYQDSEHRSQYRILTWQRRDTVTWLLFLLGFVAILIFRHW
What is the function of this protein?
Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS9_BUCAI
Sequence: MIQTQNYGTGRRKSSSARVFLRSGNGEIVVNKRSLNEYFGRETSCMIVRQPLELVDMVDKFNIYITVKGGGISGQAGAIRQGITRALIKYNQTLRFELRKAGFVTRDSRQVERKKVGFRKARKRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: L83L_ASFK5
Sequence: MDTSLKKNNGALEADNKNYQNYKDEPDKISDVLDDTKYNSMVECCHKNYSTFAPQWDVKERNYIDVPEGPSAKKSIVHRCTII
What is the function of this protein?
May subvert the host innate immune response by interacting with host IL1B and interfering with its function.
What are the official names of this protein?
Protein L83L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus L83L family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RL16_ALKOO
Sequence: MLMPKRVKRRRVHRGKMRGQAHKGNTISYGEYGLMAMEPAWITSNQIEAARIAMTRYIKRGGKVWIKIFPHKPVTKKPAETRMGAGKGSPEYWVAVVKPGRVMFELSGVSEERAREAMRLAMHKLPIKCKFVTREDQEVKGGEANEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PELA_ASPFN
Sequence: MKITSTIPAVLLGLAPLSAAVSVSGSAEGFASGVTGGGDAEAQIPSDIDELKEWLTDDTPRVIVLDKEYDFTESEGTTSGTVCASWGTGSGCQKIIQDDCGDSPSSQATWYTAGTTGIDVASDKTILGDGDKGVIKGKGLRFRDGVSNIIVQNIEISDLNPEYVWGGDALYFDGSDLIWIDHVTTARTGRQHYTFGYETNTRITLSNNFINGETTYSTGCDGYTYWTFEMVGEADQITLQNNYIYMTAGRSPALSGGTLLHAVNNVWEKNNGHALEGGDAGARGIFEGNAWIGVSTIVGDYAGRLFNAPDSSSAGDCESALGRACEVNAVSDSGDLTAYTDTSFFSDFSGLTIAPATSATDAQSSVPNNAGMGKL
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
What are the official names of this protein?
Probable pectin lyase A, PLA.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADA_CLOK1
Sequence: MDDLFLVNEINRLKIERDACILAHNYQLPEVQDIADIVGDSLALSRAAAETTNKVIVFCGVKFMAESAKILSPDKTVLIPSKYAGCPLADSITKEQLEMEKKKHPEAEVICYVNSSAEVKAVSDVSCTSSNAVKVVQNSKSNKILFVPDENLAGYVAEQIPDKEIIPWAGHCITHARITVDDVIKAQEEHPEAEMLVHPEVSEEIRENADFVGSTSAIINYAKNSDSKEFIIGTEIGVLHKMKKDSPEKQFYLLSPRLVCENMKMTRLVDVYNSLMNMQYEVFVPENVRIKALGSLEKMISIE
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_IDILO
Sequence: METVVAFTAIAVSIMIGLAALGTALGFGILGGKFLEAAARQPELAPQLQVKMFIVAGLIDAIAMIGVAVALLFTFANPFLTQVAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGB_METMA
Sequence: MELKRENVLIEALPYMQEFYDSIMVIKVGGNAMVSAQIMEDIIKDIVLLRYVGIKPVIVHGGGPEITEKMERMGKKAEFFQGLRITDDETMEIARMVLVGNINTKIVSLIGLFGGKGVGFTGYDGRMILGHKQAAKHVLIDGVETEVDIGWVGESEVINPEILHIMLEKGYIPVISPIAVDAKGNALNINADTVAGDIAAALHAKKLILMTDVSGLLRNIKDPGSRISRVKLDDIDLLIEEGVISGGMIPKIKGAAVAVKSGVERAHIINGSVSHSMLLELFTDGGVGTMIY
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_GLUOX
Sequence: MAENGKTVQVTQIASVIGRKPGQAETITGLGLRGIGSTRTLEDTPAVRGMIRKVAHLIKVEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RS17_RICCK
Sequence: MPKRVLQGVVISSKADKTVTVKVERKFKHPIYKKFVKVSKKYAAHDSENRYQEGDKVSIIESRPISKTKTWIVVNGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: UGTP_BACCQ
Sequence: MIKNPKVLILTAHYGNGHVQVAKTLEQTFRQKGIKDVIVCDLFGESHPVITDITKYLYLKSYTIGKELYRLFYYGVEKIYDKKIASWYANFGRKRLKLLLQAEKPDIVINTFPIIAVPELKKQTGISIPVYNVLTDFCVHKIWIHREVDRYFVATDHVKKVMVDIGVPAEQIVETGIPIRSSFELKINSDIIYNKYQLCKNKKILLIVAGAHGVLGSVKELCQSFMSVPDLQVVVVCGKNEALKQDLLGLQEKNPDALKVFGYVENIDELFRVTSCMITKPGGITLSEAAALQVPVILYKPVPGQENENAMYFERKGAAVVIRDDSEVFAKTEALLQDDMRLLQMKEAMKSIYRPEPADHIVDTILAENHVEPNHIPIKSPALAQSFT
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: ATG9_KLULA
Sequence: MTDSQDKVNGGSKNTFLSRVFGVHSSAVENSLDAAEMSHITMPTEQDFSNYAEDEGNVRLIESDQEPSSSNEDSNDEEPLIQQPQSIRFDTASDGMATIQSESEPDEGGTEEDEVHLEEEDFSDQDLASSVSKYGQPSSSEDEEPLSNRDSNRGSDETIPFIGRQRLNLGGKNPITGATKSTKNPSESRVFERLLGNSPAKMFRNNGRPNNLEESFLFRKPSVAEQSGPGKSTHFNLKPPPIFNNISTLTSTSKNSLSSLSPKERALWKWANIENLDTFLQQVYEYYLGNGFYCIITEKVIHLATILFVVFISTYMGHCIDYSRLSSSHTFEEIHIEQCYKTQISPTAKVFLWIFYAFIGLKVLQLYFDVKALKDIRNFYNYLLSISDKDLQTIPWQSVIQQLVLLKDQNAITANATEVKAKNRLSAHDVANRIMRKENFVIALYDNNILDLSLPVPLLRTCALTKTLEWNINLCILGFAFNEKGYLKQAFLRESQREYLGEELKKRFVLAGFLNIILSPFLVTYFVLLNFFRYFNEYKTSPGSIGSRQYTPIAEWKFREYNELYHIFQKRMRLSMIIADNYVNQFPNTLLSLTLSFIQFVSGSFVAILGILTIFDPDNFLNFEITPDRTVLFYMTVFGTLWAVCHSSINDEYTVLKPEETLEELVSYTHYAPKEWKGKYHTEDIKNEFCRLYNLRITLLLRELVSIIITPFILWFSLPKNSERIIDFFRECTVYEEGLGYVCKYAMFEATKIDKGTKAKKQTKRMFSQAEQDDSETESDEGVNKMLQSYMYFVDDYKNAGNAVGKNQLPASPIEPSYHPYSSTKDYSWKTQFALGKNSNRKRNLNRSRVKRFPDRSSDLELGSLSGSLINKSTLFKDDIADNADELKAGNGVMGLLNQYYKKSDRNR
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ATPK_BOVIN
Sequence: MASVVPLKEKKLLEVKLGELPSWILMRDFTPSGIAGAFQRGYYRYYNKYVNVKKGSIAGLSMVLAAYVFLNYCRSYKELKHERLRKYH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane.
What are the official names of this protein?
ATP synthase subunit f, mitochondrial, ATP synthase membrane subunit f.
What is the protein family that this protein belongs to?
Belongs to the ATPase F chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YQGF_BORPA
Sequence: MPEETLLAFDFGEKKIGIAIGNTLTRQARPLEIIFSETRAARFGRIGQLLQEWQPQRAVVGLPLTLDGQEQPASARARRFANQLHGRFGLAVELVDERGSSMEAQQLLGTHAADDAVAAAVILQRYLDTLPQP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.