PharMolix/UniProtQA huggingface dataset:
Protein: PHLPP_DROME
Sequence: MLKATRKQADPYKSKLKVSASHSGPHPLPVEVTAAEEEQAATFGQTSPQKLSLKGSQLGGSILIGNYNYLTQLEVCENEMEVLDLSSLAQLETLKCSRNKLMELIINGTNLQTLVADHNYLHNISTTNTHPVPLKLQRIDISHNNFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLNVSCNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTPQLAKLAMLKVLDLSHNHLDRVNLLALVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVSGNNRAALPTTKIRQVSAQRNQNKTSGPWTMGFAETPGSGDCRKLSVYQLRAANYGGSDEALYGMFEALEGRGRAAQEMSHLVPDLMKQEQMVKDSAVRDYMKFTLLAAQQQCGSVRSAALFHLTRTRAPSKVRPLKSKRYVLRMASTGGLDAYLIRRTSQLRLTKPDVIQKDQIHSMPDPHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIRKEENSLLAAKRLVDIAQSFAAAESLSVIVVRFRHLGTDVDHLIRELKQSVRKKPQPVSLPLSSGSVCKRTCCDRSNACRHRAIEQEPLAGRSSPSGQSDRDLLAKDKDDEFVLAHARVLQEEQQLEMLDETESVSESVLSEEQFKCWEYMLEQNTQLLFDKELNTISKSFTKQRTVPNAIMAATVLPERNDFTSNLMRTVTNKFISTSTPQLPQPITTSVPLGSYHQVKQAPPGHFGSALSFQQAHSYGYNLFDAKPRPKFHGGTVKRSAGPNSAYFGSLQRLMPYNFEYDFAVTQERERNILDEEEHDDDDFNEHESRMRKYWGVATTEL
What is the function of this protein?
Protein phosphatase that specifically mediates dephosphorylation of 'Ser-586' of Akt1, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes.  Dephosphorylation of 'Ser-586' of Akt1 triggers apoptosis and suppression of tumor growth.
What are the official names of this protein?
Protein phosphatase PHLPP-like protein, PH domain leucine-rich repeat protein phosphatase, dPHLPP.
Protein: I15RA_MOUSE
Sequence: MASPQLRGYGVQAIPVLLLLLLLLLLPLRVTPGTTCPPPVSIEHADIRVKNYSVNSRERYVCNSGFKRKAGTSTLIECVINKNTNVAHWTTPSLKCIRDPSLAHYSPVPTVVTPKVTSQPESPSPSAKEPEAFSPKSDTAMTTETAIMPGSRLTPSQTTSAGTTGTGSHKSSRAPSLAATMTLEPTASTSLRITEISPHSSKMTKVAISTSVLLVGAGVVMAFLAWYIKSRQPSQPCRVEVETMETVPMTVRASSKEDEDTGA
What is the function of this protein?
High-affinity receptor for interleukin-15 (PubMed:17947230).  Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (PubMed:17947230).  In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (By similarity).  In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (By similarity).
What are the official names of this protein?
Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Cell surface. SUBCELLULAR LOCATION: [Soluble interleukin-15 receptor subunit alpha]: Secreted, extracellular space.
Protein: DOIAD_MICEC
Sequence: MGGRMRALQFHGGHKAQIIDTPRPEAPPGWAVVKVHYCCLCGSDLWLYRGKWHGNRYPIVPGHEWAGVVDSAPEGYESWVGRPVTGDLIVGCQGCGPCRDGLPVMCENLIEIGFTVDGGCAGYVAVPITNLYLLPEGMDLAAASQTEPLAVALHAVDRINLRPAERVAVLGAGGIGQLILQSARATGATVTLATDLVAERRKIAEESGAAAAVHPSELPELTSYADKVDVVFEASGDPESVVRALDLVRPGGRVCLVGYQVGAEHALETARLPLSYASLVGVMGPGGKYREAVDLLANGAIDTQPILTDIVTLDDYAPAIDRAINRTDGTVRVVFDLRNE
What is the function of this protein?
Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD(+) or NADP(+), forming 3-amino-2,3-dideoxy-scyllo-inosose (amino-DOI).
What are the official names of this protein?
2-deoxy-scyllo-inosamine dehydrogenase, DOIA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. DOIA dehydrogenase subfamily.
Protein: FPG_HYDCU
Sequence: MPELPEVETTRKGIQPKVEGQAIQKIIIRNGKLRWPVDPSLVEKLPGLVVLSIKRRAKYLLLETDQGHLIIHLGMSGNLRVLPQHEPAVKHDHIDLLLENGFLLRYHDPRRFGSWLWTEAPIQEHSLLKSLGPEPLTDAFNAEYLFQKLQGRKTAIKTFIMNNQIVVGVGNIYANESLFLSGIHPTRPAQSLTLTEATKLTAHIKTVLSAAIEQGGTTLKDFLTPDGKPGYFEQKLNVYGRENLPCPQCDSAIEKVVLNQRAAYFCSNCQKQLDSTVKIK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL36_POLNS
Sequence: MKVLASVKCICRNCKIIKRKRVVRVICSSDARHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: Y194_STRPN
Sequence: MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYVLLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE
What are the official names of this protein?
UPF0473 protein SP_0194.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: DNLI1_XENLA
Sequence: MQRTIKSFFQPKLGAEVKTKEEKVKNDVQKEKEEPEKSVPERPLKERNGRALCGDTESPVKRVSKKSARVLESDSEEEEENSKVQATPEKMNNESDPKNDVKETPPSARKETPPSARKETPPSARKETPQSARKETPPSARKDAKSEGASEMNTSQDFVSPCSSKSIDSPLCSDSPGISPSGIPKRKTARKQLPKRKLEISPSESNPPKDDFDVKGAVKRQKKEAEGDIQQEEPMETSHNISMEEECPIKKETNPDVVQETISNADDPNIELVDQKDVVSGEKQSEPKCQEQPQPKLTSPTVEPKASKGKARKKNSPLPKKVKFSDKVSFKDNDSEEKSNEEKSDEEPQKKADSAKPVKQISSFFAPRKPAIKTEKREENLNEKNVTETSLEESPKPKKNVGSFFGASKQEATEEQTEYNPSKSKYHPIDDACWCNGQKVPYLAVARTFERIEEESARLKNVETLSNFLRSVIALTPEDLLPCIYLCLNRLGPAYEGLELGIGETILMKAVAQATGRQLEKIKAEAQEKGDLGLVAESSRSNQRTMFTPPKLMASGVFGKLKDIARMTGNASMNKKIDIIKGLFVACRHSEARYIARSLGGKLRIGLAEQSVLSSIAQAVCLTPPGRDAPPTVMDAGKGMSADARKSWIEEKAMILKQTFCELPNYDAIIPILLEHGIDDLPKHCRLTPGIPLKPMLAHPTKGIGEVLKRFDEAAFTCEYKYDGERAQIHILENGEVHVYSRNQENNTTKYPDIISRIPKIKKESVKSCILDTEAVAGDAEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDMLYLNGESLVKEPFAKRRQLLRDSFLETEGQFMFATYMDKSNTDEISEFLDQSIKDSCEGLMVKTLEQDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGKGKRTGIYGGFLLASYDEESEEYQTICKIGTGFTDDDLEKHYNFLKDHVIENPRSYYRWDSATEPDHWFDPVQVWEVKCADLSISPVHKAALGLVEDQKGISLRFPRFLRIRDDKKPEESTNSFQVADLYRKQQQIQNTSSTEKAEEDFY
What is the function of this protein?
DNA ligase that seals nicks in double-stranded during DNA repair.  Also involved in DNA replication and DNA recombination.
What are the official names of this protein?
DNA ligase 1, DNA ligase I, Polydeoxyribonucleotide synthase [ATP] 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABZ_BRASO
Sequence: MEESPIKFADIDINEILKTLPHRNPFLLIDRVKNIRADYSGIGVKNVSFNEPCFQGHFPERPVYPGVLMIEGMAQTAGVIGIKSVEGTEKPRAVYFLTIDKCKFRKPVLPGQTIEYHMRSIGRRKTMWWFHGDAKVDGVVVAEADVGAMLTD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_THEPX
Sequence: MGTAKEKKQQIVAEFKDKLSRAQTVIFSNFSGLTVEDDTILRRKFREANSEYKVYKNTLMTIAAKELGYGDDLIKYFEGPTSVAFGYDDPVAPAKVLVEFMKDHKGIELKAGLVNGKLVTVEEIKALAELPSREELVAKALGSMKAPITNLVFVLSGTLRSLLYALNAVKEKKQAEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CP39A_HUMAN
Sequence: MELISPTVIIILGCLALFLLLQRKNLRRPPCIKGWIPWIGVGFEFGKAPLEFIEKARIKYGPIFTVFAMGNRMTFVTEEEGINVFLKSKKVDFELAVQNIVYRTASIPKNVFLALHEKLYIMLKGKMGTVNLHQFTGQLTEELHEQLENLGTHGTMDLNNLVRHLLYPVTVNMLFNKSLFSTNKKKIKEFHQYFQVYDEDFEYGSQLPECLLRNWSKSKKWFLELFEKNIPDIKACKSAKDNSMTLLQATLDIVETETSKENSPNYGLLLLWASLSNAVPVAFWTLAYVLSHPDIHKAIMEGISSVFGKAGKDKIKVSEDDLENLLLIKWCVLETIRLKAPGVITRKVVKPVEILNYIIPSGDLLMLSPFWLHRNPKYFPEPELFKPERWKKANLEKHSFLDCFMAFGSGKFQCPARWFALLEVQMCIILILYKYDCSLLDPLPKQSYLHLVGVPQPEGQCRIEYKQRI
What is the function of this protein?
A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis (PubMed:25201972, PubMed:10748047).  Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver (PubMed:25201972, PubMed:10748047).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:25201972, PubMed:10748047).
What are the official names of this protein?
24-hydroxycholesterol 7-alpha-hydroxylase, Cytochrome P450 39A1, hCYP39A1, Oxysterol 7-alpha-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Protein: SSPC_STAAN
Sequence: MYQLQFINLVYDTTKLTHLEQTNINLFIGNWSNHQLQKSICIRHGDDTSHNQYHILFIDTAHQRIKFSSIDNEEITYILDYDDTQHILMQTSSKQGIGTSRPIVYERLV
What is the function of this protein?
Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme.  Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B.  Also involved in growth capacity, viability and bacterial morphology (By similarity).
What are the official names of this protein?
Staphostatin B, Staphylococcal cysteine protease B inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I57 (SspC) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC079_HUMAN
Sequence: MHVCDLQKLVRIQLAFTTFPWMFSCHLLPTPELSSKRNQCLLYKTSGCLTQMPILYGHPATLLKDYILQAILQPGKKIQGGTEIQRGSFANQYQTDASHL
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC02877.
Protein: RL34_RICPR
Sequence: MKRTFQPSNLVRKRRHGFRARMITATGRAILKKRRAKGRHKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: MENC_BDEBA
Sequence: MIKISYSPYTLKPVQSLNAATAATAREGVLLKVEWNDGLYGFADLHPWPELGDLSLEEQLSDLRMGRMTTQIEQSIWLARRDALLRKEKKHVFDGGEKIKNNYLLSHFQDLKPGFLDGLKNEGYNTVKVKMGRDLQKEADMLTHIAASGMRMRLDFNALGSWQTFEKFMVNLPLTVRPLIEYVEDPFPFDFHAWGEARKLAKIALDNQYDKVPWGKIASAPFDVIVIKPAKTDVDKAVAQCQKWNLKLAVTSYMDHPVGVVHAVGVAMELKDKYGDMILESGCLTHRLYQMDSFAAELSTQGPYLLKNKGTGVGFDKLLEALTWYQLKVR
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24872444).  Does not show N-succinylamino acid racemase (NSAR) activity with N-succinyl-L-phenylglycine as substrate (PubMed:24872444).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: SYGA_LACLS
Sequence: MANKKLAFQDIILTLQGFWSKQGANLMQAYDNEVGAGTMSPYTFLRSNGPEPWGAAYVQPSRRPADGRYGENPNRLFQHHQFQVVLKPSPKNIQELYLQSLAALGIDALEHDIRFVEDNWENPSMGCAGIGWEVWIDGQECTQFTYFQQVGGIEVDSVTSEITYGLERIATVIQEVDSVYDLEWGNGVAYGDIFKEPEYEHSKFAFEESNQELLLKLFGEYEQEALDLLDKGLVHPAYDYILKSSHTFNLLDARGAVSVTERAGYMHRVRTMARKVAKTFIEERAKLGFPLLKDEALREKYLGKKGKYTKIVEGEEK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIUH_CAUVC
Sequence: MSGLTTHILDQASGKPAAGVGVRVSRRDGEQTQWLAELRTDADGRARLVAGEDLAVGGYRLEFAIGDHFKASGLPVSDPPFLDVVVIDFAVSNLDQHWHVPLLVSPYGYSTYRGS
What is the function of this protein?
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
What are the official names of this protein?
5-hydroxyisourate hydrolase, HIU hydrolase, HIUHase.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
Protein: PSBI_SOLTU
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RRF_STAAB
Sequence: MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPEARLLVISPYDKTSVADIEKAIIAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQKATDNSIKEIDQMIADKEKDIMSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAM3C_RAT
Sequence: MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGSLFARSALDSAIRSTKPPRYKCGISKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALVNGKTGDVIDTKYFDMWGGDVAPFIEFLKTIQDGTVVLMATYDDGATKLTEEARRLIAELGSTSITSLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD
What is the function of this protein?
May be involved in retinal laminar formation.  Promotes epithelial to mesenchymal transition (By similarity).
What are the official names of this protein?
Protein FAM3C, Interleukin-like EMT inducer.
What is the protein family that this protein belongs to?
Belongs to the FAM3 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle.
Protein: ERA_MYCPU
Sequence: MKILFSTIIGRPNVGKSTLLNNILEYDLAIVSSKPQATRDQIMGIYSDDDYQLIFTDTPGIYKTKTKFGENLNAQSYESLKDIDLVIFLSPANEEIGPGDEFICEKIKNFTNKIALITKIDLENSEEVLKKKAEKLKSLGFKEIFAISSKDHGSIKKLINEIKKYSYEGERQFDEDMITEKSEKFIAKESIREACIDLLEQELPHSILVEIDSFSEEEREEKNLVEIHSTIYVNKESQKGILIGKGGSKIKKIGISARKKIQRKLGVNVKLFLKIKVKKNWVNQEKIFKKFDN
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: RL37A_SACS2
Sequence: MGKVTGISGRFGARYGSTLRKKWKEIMEKRYDEHQCPYCKTTGKVIRLASGIWYCKKCNSKWAGLAYTPY
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
Protein: GHRA_CROS8
Sequence: MDILFYHPTFDISEWAALLQRHLPHARLRAWQPGDNAAADYALVWHPPYDMLRGRVDLKAIFALGAGVDSLLSRLNEYPDLLPSGVPLYRMEDTGMAAQMQEYAISQVLHWFRRFDDYAALQREARWEPLEEYRHADFQVGVLGAGVLGGQVAQSLSRMGFPVRCWSRSCKALPGVESFAGPDELSAFLHGTRVLINLLPNTPETVGIINAQLLAALNDNAYVLNLARGVHLVEEDLLAALDRGKVKGAMLDVFQQEPLPHESPLWRHPRVRITPHVAAVTRPEEAVAFIAQSITRIERGDIPPNQVDVARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNLOX_NAKOS
Sequence: MRIGLLAFAVAARYVEALPVASGEEVASSSAPTTLPSTSSSSALPSPTKYTLPHEDPNPEARKAEIALKRGGFLYGPSTLGQTTFYPSGTLGTAMSQRDQALWLRDAENQTITAYREANETLRDIQSHGGLKTLDDFALLYDGHWKASVPEGIEKGMLSNYTSDLLFSMERLSNNPYSLKRLHPTKDKLPFSVEDKVVKQLTATTLAALHKAGRLFFVDHSDQKKYTPQAGRYAAACQGLFYVDARSNQFLPLAIKTNVGADLTYTPLDDKNDWLLAKIMFNNNDLFYSQMYHVLFHTVPEIVHMAAIRTLSESHPVLAVLNRIMYQAYAIRPVGERILFNPGGFWDQNLGLPATAAVDFLSSIYAHGEGGFRAGYVENNLRKRGLVGDTFGGPALPHFPFYEDAQRVLGAIRGFMQAFVDSTYGGDDGALARDFELQDWVAEANGPAQVRDFPTAPLRRREELVGILTHIAWNTGGAHHVLNQGAPVRASGVLPLHPAALYAPVPAAKGAVASSDGLLAWLPDEVKSVEQVSLLARFNRAQVRDRNQTVRNMFAAPELLAGNGEAYAAANARFVEETGRISREIEGRGFDSKGLSQGMPFIWTALNPAVNPFFLSI
What is the function of this protein?
Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 9S-, 11- and 13R-hydroperoxy fatty acids.  At the end of lipoxygenation, the intermediate products 11S-HPODE and 13R-HPODE from linoleic acid are then transformed into 9S-HPODE as the final product.  The intermediate product 11R-HPOTrE from alpha-linolenic acid is transformed into 9S-HPOTrE and 13R-HPOTrE as the final products.  9S-HPOTrE is further oxidized by the enzyme to 9,16-DiHOTrE as the end product.  Also acts on gamma-linolenic acid producing 9-HOTrE(n-6) as the main metabolite.
What are the official names of this protein?
Manganese lipoxygenase, MnLOX, Linoleate 9S-lipoxygenase, Linoleate 9S-LOX, Manganese 9S-lipoxygenase, 9S-MnLOX.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family. Manganese lipoxygenase subfamily.
Protein: Y657_PASMU
Sequence: MYDYILNALVKIEAYLDNESDSVEIPNNLFKTDILVDYYYYPGHFVDVDDDEKELIAATLTDAGYADHYDALAELLWKANIEPIPKEELVDGNSYCFIMISFGITPVQAHLKAKKAKYEQVTFFCLPYTDREGEQRFKILVVPNTFGSIFKEMKCACLLDIESEEQLDKTYWSLLERAIGQICQTLSIDVTGFALSDTTYQQKTLETYSPYLTQFCQLTQIQNIEGFKARWLEIQQQQKQLIQQVKDEGFYGTVKPAFLNYRFLLCEFLTSTYEDHWQMDYDALFDYLAKYLEQPFELDEEDGLQPNDIARKVEAESNYSLLDIETRLESYCFLPCLKTDVESILNLAEILDFPMSKLGD
What are the official names of this protein?
Uncharacterized protein PM0657.
What is the protein family that this protein belongs to?
To P.multocida PM1082.
Protein: ATM1_CRYNH
Sequence: MGFGSCSRHALFTPAAFSGSFTTMTTSCFKRVYTAQIHGGDALGKRLPSVSSFSGQLPRHGLHRQSLAFFSTSHRRQTSPPPSPRTTSQSPTVPSKASTTPPTSLNTSKPIATESQDKTDWSIIVKLAGNIWPKNNPNVKFRVIGALTLLVAGKVLNVQVPFFFKTIVDSLNVPITESTTVWVLAGASIAGYGAARILTTLFGELRNAVFASVAQNAIRKVARETFEHLLNMDMKFHLERQTGGLTRAIDRGTKGISFILSSIVFHVIPTALEISMVCGILSWKFGWDFAAVTAITMLLYTWFTIKTTAWRTTFRKQANAADNKGATVAVDSLINYEAVKSFNNEKYEVAQYDTTLKAYEKASVKIATSLAALNSGQNFIFSSALTMMMLLGAQGIVKGTMTVGDLVLVNQLVFQLSLPLNFLGTVYRELRQSLIDMDVMFNLQSLNSAIKDTPTAKPLHLKGGEIEFRNVAFAYHPERPIFRDLSFKIPAGQKVAIVGPSGCGKSTVFRLLFRFYDSNSGQILIDGQDIKTVTLDSLRRSIGVVPQDTPLFHADILHNIRYGNLEATDEQVYEAARKAHVEGTIQRLPEKYATKVGERGLMISGGEKQRLAVARVLLKDPPVLFFDEATSALDVYTETELMRNINSILTGQGKTSVFIAHRLRTISDADLIIVLQDGYVAEQGTHEQLLAMPGGVYHRLWQAQLTESTQPTDEEIERQREELEVVDEKKKQ
What is the function of this protein?
Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of mitochondrial Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins (PubMed:29089435, PubMed:29420779).  Hydrolyzes ATP (By similarity).  Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity).  Plays a role during copper stress, in a manner dependent on the copper metalloregulatory transcription factor CUF1 (PubMed:29089435).
What are the official names of this protein?
Iron-sulfur clusters transporter ATM1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CAPSD_TYLCC
Sequence: MAKRPADIVISTPASKVRRRLNFDSPYTGRVAAPTVRVTRRQMWSNRPMYRKPMMYRMYRSPDVPRGCEGPCKVQSCEARHDVSHTGKVICVSDVTRGNGITHRVGKRFCVKSIYVIGKIWMDENIKFKNHTNTVMFFLVRDRRPSGTPMDFQQVFNCYDNEPSTATVKNDLRDRFQVRRKFYSTVTGGQYACKEQALVKRFIRLNTHVVYNHQEQAKYENHTENALLLYMACTHASNPVYATLKVRIYFYDSQMN
What is the function of this protein?
Encapsidates the viral genome into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement.  The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).