PharMolix/UniProtQA huggingface dataset:
Protein: UREF_BURP0
Sequence: MDTAELVALLHLASPALPIGAFSYSQGLEAALDAPLIRDADGARDWIASGLADVLAQGELPFLAHQLARWHAHDAAALADANDEFVASRESFELRRETEQMGWSLAQLCASLEWGDAARRATLASIPSVALPSAFAFAAAAHGATPDAALAAYAFGWVENQTAAAIKAVPLGQLAGQKIIVALREPIRDAVRRALATPPEAINTFAPQLGILSARHESQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPD_ARATH
Sequence: MVVLAAAIVVKSGKVIVSRHYVDMSRIRIEGLLAAFPKLVGMGKQHTYIETENVRYVYQPIEALFLLLVTTKQSNILEDLATLTLLSKLVPEYSMSLDEEGISRASFELIFAFDEVISLGHKESVTVAQVKQYCEMESHEEKLHKLVMQSKINDTKDVMKRKANEIDKSKIEKNKPGGFSSMGSMGSGRLESGFNELSISSGGGGGYGSGSGFGMISDVDPINTKPKDRSRSSVTAPPKSSGMKLGKSGKNQLMESLKAEGEDVIEDVKPTGQSKAAAPPPTDPFTLTVEEKLNVALRRDGGLSSFDMQGTLSLQILNQEDGFVQVQIATGENPEILFKTHPNINRDMFNNENILGLKRPDQPFPTGQGGDGVGLLRWRMQRADESMVPLTINCWPSVSGNETYVSLEYEASSMFDLTNVIISVPLPALREAPSVRQCDGEWRYDPRNSVLEWSILLIDNSNRSGSMEFVVPPVDSSVFFPISVQFAATSTYSGLKVTGMIPLRGGGGATPRFVQRTQLIAQNYQVI
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit delta, Delta-coat protein, Delta-COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: RS3_PSEA7
Sequence: MGQKVHPNGIRLGIVKEHTSVWYADRKNYADYLFADLKVREYLQDKLKSASVSRIDIHRPAQTARITIHTARPGIVIGKKGEDVEKLRQDLTKQMGVPVHINIEEIRKPELDAMLVAQSVAQQLERRVMFRRAMKRAVQNAMRIGAKGIKIQVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATYEAHTTYGVIGVKVWIFKGEVIGGRQEELKPVAPAPRKKAAR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DAPA_BACSU
Sequence: MNFGNVSTAMITPFDNKGNVDFQKLSTLIDYLLKNGTDSLVVAGTTGESPTLSTEEKIALFEYTVKEVNGRVPVIAGTGSNNTKDSIKLTKKAEEAGVDAVMLVTPYYNKPSQEGMYQHFKAIAAETSLPVMLYNVPGRTVASLAPETTIRLAADIPNVVAIKEASGDLEAITKIIAETPEDFYVYSGDDALTLPILSVGGRGVVSVASHIAGTDMQQMIKNYTNGQTANAALIHQKLLPIMKELFKAPNPAPVKTALQLRGLDVGSVRLPLVPLTEDERLSLSSTISEL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_POPAL
Sequence: MGLPWYRVHTVVLNDPGRLLAVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTITNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQSVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVGTGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAIGWLGHPLFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGSRTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTRRQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS18_STRPJ
Sequence: MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PAKH_DICDI
Sequence: MVRLFRSGSNPKEIDISQPNSLVHKVHVDLDLNWSSGGETSFEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKKCNNPYVVSYFGSIMLKNKYWILMDYCSLSSFNDIMQSIGKTFKEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQSTFSKGSIAGTPYWMAPEILNQTDYNNKIDVWSLGIVAIELADGEPPLSEVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFIKSAKPDALKELTQMAIKLKSKKRKSIGPSVSPKQQPNDNNNNNNNNKPQFLSKLLNNNSNSSNDIGETTSGSVIYKPNVFSGSIDTGSVVIHNTITSNNNDSGSVVLNSNTVINRSKPLPPPPSYESVILNDKLKQQQQQQQQSNQQTTTTTTKQNTIKNKFNTISNTIKCNTILVQDKTLEIIQKTPMKNLDERNQKIVLYSTLGLILVLSVFFKFFK
What are the official names of this protein?
Serine/threonine-protein kinase pakH.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FBRL_XENLA
Sequence: MRPGFSPRGGRGGFGDRGGFGGRGGFGDRGGFRGGSRGGFGGRGRGGDRGGRGGFRGGFSSPGRGGPRGGGRGGFGGGRGGFGAGRKVIVEPHRHEGIFICRGKEDALVTKNLVPGESVYGEKRISVEDGEVKTEYRAWNPFRSKIAAAILGGVDQIHIKPGVKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPVIEDARHPHKYRILVGMVDVVFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFAAEVKKMQQENMKPQEQLTLEPYERDHAVVVGIYRPPPKQKK
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins.  Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA.  Probably catalyzes 2'-O-methylation of U6 snRNAs in box C/D RNP complexes.  U6 snRNA 2'-O-methylation is required for mRNA splicing fidelity.  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin, Histone-glutamine methyltransferase, U6 snRNA 2'-O-methyltransferase fibrillarin.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Fibrillar region of the nucleolus.
Protein: O161_CONLT
Sequence: MKLTCVLIIAVLFLMDNQLITADYPRDEQVYRAVRLRDAMQKSKGSGSCAYISEPCDILPCCPGLKCNEDFVPICL
What are the official names of this protein?
Conotoxin Lt6.1, Lt6a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: G6PD_AGGAC
Sequence: MKAENCCIVIFGASGDLTYRKLIPALYNLYKIDRLGEDFSVLGVARTELNDKSFREKMRQTLIKNEGAKGECLEQFCSHLYYQAVNTADKADYAKLVPRLDELHDTYRTEGNTLYYLSTPPSLYGVIPECLGEHGLNKEDRGWKRLIVEKPFGYDRETAEALDIQIHRFFEEHQIYRIDHYLGKETVQNLLVLRFSNGWFEPLWNRNFIDYIEITGAESIGVEERGGYYDGSGAMRDMFQNHLLQVLAMVAMEPPVIINANSMRDEVAKVLHCLRPLTQEDVEHNLVLGQYVAGEVDGEWVKGYLEEKGVPPYSTTETYMALRCEIENWRWAGVPFYVRTGKRLPARVTEIVIHFKTTPHPVFSQNAPENKLIIRIQPDEGISMRFGLKKPGAGFEAKEVSMDFRYADLAGATVMTAYERLLLDAMKGDATLFARTDAVHAAWKFVQPILNYKAQGGRLYDYEAGTWGPTAADKLIAKSGRVWRRPSGLMKKKV
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: OPPC_HAEIN
Sequence: MTDYRTQPINQKNADFVEQVADRIEEMQLEGRSLWQDAKRRFFRNKAAVASLIILAFIIIFITVAPWFFPFTYEDTDWNMMSAAPTMEGYHFFGTDASGRDLLVRTAIGGRISLLVGIAGAFISVTIGTIYGAISGYVGGKTDMLMMRFLEILSSFPFMFFVILLVTLFGQNIFLIFIAIGAIAWLGLARIVRGQTLSLKNKEFVEAAIVCGVPRRQIILKHIIPNVLGLVAVYASLEVPGLILFESFLSFLGLGTQEPMSSWGALLSDGAAQMEVSPWLLIFPAFFLCLTLFCFNFIGDGLRDALDPKDR
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Oligopeptide transport system permease protein OppC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNME_EXIS2
Sequence: MMEFDTIAAISTPMGEGAIAIVRLSGPKAVETADRVYRGANRLTDVPTHTIHYGKLVEQTTEQVVDEVMVSVMRAPKTFTREDVVELNCHGGIVAVNRVLELILEQPDVRLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMTVAVGQIEGRLSKLVQDLREQLLQTIASIEVNIDYPEYDAEEMTQQIVQKDAGEVRRILTELLATARQGKILREGLSTAIIGRPNVGKSSLLNTLVQEAKAIVTDIAGTTRDTIEEYVNVRGVPLKLIDTAGIRETEDIVERMGVEKSRQALNSADLILLVLNGNDALTEEDVLLFEAIRGMNAIIIVNKSDLTQAIDLTRVSELADGRPVVTTSLLEEAGVTDLEAAIASLFFEQGVEGQDMTYVSNARHIQLIKQASQMIEDALGAAEASMPIDMVQIDLRRAWDTLGEINGDTAQDSLLDKLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_STRSY
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFTFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTRAQVQKIAETKMPDLNAASLEAAMLMIEGTARSMGFTVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL18_CHLPN
Sequence: MESSLCKKSLMKRRRALRVRKVLKGSPTKPRLSVVKTNKHIYVQLIDDSIGKTLASVSTLSKLNKSQGLTKKNQEVAKVLGTQIAELGKNLQLDRVVFDRGPFKYHGIVSMVADGAREGGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RNH3_STRPS
Sequence: MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFVTPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAVSVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEGKYLAVAVSSVIARDLFLENLENLERELGYQLPSGAGTASDKVASQILQAYGMQGLNFCAKLHFKNTEKAKNA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_VIBC3
Sequence: MDHFLHIDVNAAQAMMEQKQAHLVDIRDPQSFQLAHAKNAYHLTNQSMVQFMEQAEFDQPVLVMCYHGISSQGAAQYLVNQGFEEVYSVDGGFEAWHRANLPIEAS
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEE_FLAPJ
Sequence: MLTKEIQIAVEKGEMLPLMEEFYTIQGEGYHTGTAAYFIRIGGCDVGCHWCDVKESWNAALHPPTKTDVIVENATKYAKTIVVTGGEPLTWDMTVLTQRLKAENLQVHIETSGAYPVTGAWDWFCLSPKKNKLPVAEAYEIAHELKVIIYNKHDFIFAEEQAAKVNKNAILFLQSEWSKKEEMTPFIVDYVMNNPKWRVSLQTHKYLNIP
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: RS19_METPB
Sequence: MARSLWKGPFVDGYLLKKADAARGGSRNEVVKIWSRRSTILPQFVGITFGVHNGHKHIPVYVTEEMVGHKFGEFSPTRTFPGHAADKKAKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ARX_RAT
Sequence: MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRTDQEKAMQGSPKGSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAGAVAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVAHPEERLSAASGPGSAPAAGGGTGTEEDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC
What is the function of this protein?
Transcription factor.  Binds to specific sequence motif 5'-TAATTA-3' in regulatory elements of target genes, such as histone demethylase KDM5C.  Positively modulates transcription of KDM5C.  Activates expression of KDM5C synergistically with histone lysine demethylase PHF8 and perhaps in competition with transcription regulator ZNF711; synergy may be related to enrichment of histone H3K4me3 in regulatory elements.  Required for normal brain development (By similarity).  Plays a role in neuronal proliferation, interneuronal migration and differentiation in the embryonic forebrain.  May also be involved in axonal guidance in the floor plate (By similarity).
What are the official names of this protein?
Homeobox protein ARX, Aristaless-related homeobox.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACSA_NITEC
Sequence: MATIESILRENRIFPPANEFVRHANITGMKTYEALRQEAERDYAGFWAKLAKQYITWHKPFTRILDDTNPPFYKWFDDGELNISWNCLDRHLTTQANKTAIIFESDEGEVIRCSYRELHQRVCRFANGLKALGIRQGDRIVIYMPMRIEAVVAMQACARIGVIHSVVFGGFSAKSVYERIIDAGASAVITADEQTRGGKRHALKATVDEALAMGDTTSVHSVIVFRHTGTDIPWQPERDRWWHNLTASQSDECEPIWVNAEHPLFTLYTSGSTGKPKGVQHSSAGYLLGAIVSMQWVFDYHSEDIFWCTADVGWVTGHSYVTYGPLAIGATQVIFEGTPTYPHAGRFWEIIQKHRVTTFYTAPTAIRSLIKLGPDLPEKYDLSSLRLLGSVGEPINPEAWMWYYTVIGQSRCPVVDTWWQTETGSHMIAPIPGAIPAKPGSCTLPLPGIDAAVVDETGLPAEQGKGGFLVIKRPFPSMLRTLWNDPERFRNTYFPADIAGGHYYLAGDSAHRDQDGYFWIMGRIDDVLNVSGHRLGTMEIESALVAHPLVAEAAVVGKPHEIRGEVIVAFVVLRGKLPDDQQAAEIAETLREWVSSEIGAIARPEEIRFGENLPKTRSGKLMRRLLRSLARGETITQDISTLENPVILEQFSQTI
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: MURD_BACAH
Sequence: MKTVTEFQNKNILVLGIAKSGYAAATLLQKLGANVIVNDGKPLAENVLAAELQAKGMDVVCGGHPLELLERNISLVVKNPGIPYSNPILVAAKEKQIPIVTEVELAYRISEAPFVGITGSNGKTTTTMLTFEMLKEGQKHPVIAGNIGTVACEVAQDAKENEVVVTELSSFQLMGVELFQPKIAAFLNLFEAHLDYHGTKKEYGLAKANIFKNQTENDYSVINADDADVMALSAYSKGQKVLFSTTKEIEDGACIKDNALYFKAEKVVEVDDIVLPGQHNLENILAAMSIAKLLGVSNEAITAVLKRFTGVKHRLEYVTTINNRKFYNDSKATNMLATEKALSAFTQPTVLLAGGLDRGNEFDDLIPYFKNVKAIVTFGQTAPKLVRAAEKAGLETIESVDTLDEAVVKAYAHSTDGDVILLSPACASWDQFKTFEERGDIFIQAVHKLI
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_YERPE
Sequence: MTDKSTARKKITRIGIGGPVGSGKTAIIEVITPILIKRGIKPLIITNDIVTTEDAKQVKRTLKGILDEEKILGVETGACPHTAVREDPSMNIAAVEEMEERFPESDLIMIESGGDNLTLTFSPALADFYIYVIDVAEGEKIPRKNGPGLVQADILVINKIDLAPYVGASLDVMESDTKVVRGNRPYILTNCKTGQGIEELVDMIMRDFLFTHVQPEGEQA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_VIBVU
Sequence: MKNAVHFGAGNIGRGFIGKLLADANVAVTFADVDAPLVDQLSHKQEYKVKVVGSECQIDTVTHVTAVNSASEEVIDRIVQTDLVTTAVGPNVLDIIAKTIAQGIAKRFAAGNLAPLNIIACENMVRGTTHLKGEVYKHLDASLHAQADELVGFVDSAVDRIVPPAEAANDDPLEVTVESFSEWIVDEQQFKGEVPSIAGMEKTHNLMAFVERKLFTLNTGHCITAYLGCLQGHRTIREAIENPAIRDQVKQAMMESGEVLIRRYGFDREMHQAYIEKILARFANPFLVDEVDRVGRQPIRKLGMNDRLIKPLLGTIEFGTANQHLLKGIAAALKYQNDSDPQAVELQRSLQQVGVKKTLAKYTSLAEDSVEVAKIETLYNQL
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RS16_EHRCJ
Sequence: MSVKIRLARFGAKKRPFYRVVVADSRVSRDGKFIESLGFYNPMLPKEHELFVKVKVDRLKYWLSVGAQATDRVAWFIKKGIINIETV
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RS13_BORAP
Sequence: MARISGIDLPSNKQLKIALTSIYGIGRTRALEVCNKADISSSKIAKDLDNDEVNRLRKVIESDYVVEGKLRSEVAMSIKRLMDIACYRGVRHRKGLPLRGQRTKTNARTRKGKRKTVANKKIASK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RS12_SALPA
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL3_LYSSC
Sequence: MAKGILGRKIGMTQVFAENGDLIPVTVIEATPNVVLQKKTVETDGYEAIQVGFEDKRVKLSNKPQQGHVAKANTAPKRFIREFRNVNVEEYEVGQEVKVEIFAEGDVIDVTGVTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKQKKLPGQMGGNVVTIQNLEIVKVDTDRNLLLVKGNVPGSKKALVTVKTASKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y104_BORPE
Sequence: MHNIPPEESLIEYPSDFPIKVMGKQHPEFAQTLTEVVLQFDPGFDPASVEMRPSKGGNYLGLTFTVRATSREQLDSLYRALHGHPMVSIVL
What are the official names of this protein?
UPF0250 protein BP0104.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: HPS_STAES
Sequence: MELQLAIDLLNKEEAAKLAQKVEEYVDIVEIGTPIVINEGLPAVQHLNENINNAKVLADLKIMDAADYEVSQAVKYGADIVTILGVAEDASIKAAVEEAHKHGKALLVDMIAVQNLEQRAKELDEMGADYIAVHTGYDLQAEGKSPLDSLRTVKSVIKNSKVAVAGGIKPDTIKDIVAEDPDLVIVGGGIANADDPVEAAKQCRVAIEGK
What is the function of this protein?
Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
What are the official names of this protein?
3-hexulose-6-phosphate synthase, HPS, D-arabino-3-hexulose-6-phosphate formaldehyde lyase.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. HPS subfamily.
Protein: VES_ECO55
Sequence: MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIAANGEFSLFPGMERIVTLLEGGEMLLESADRFNHTLKPLQPFAFAADQVVKAKLTAGQMSMDFNIMTRLDVCKAKVRIAERTFTTFGSCGGVVFVINGAWQLGDKLLTTDQGACWFDGRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ
What are the official names of this protein?
Protein Ves.
What is the protein family that this protein belongs to?
Belongs to the Ves family.