PharMolix/UniProtQA huggingface dataset:
Protein: ATPE_SHIDS
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: POLK_CAEEL
Sequence: MLTFNDNKAGMNGLDKEKITKVIEENTSASYSSFSKKQQSRIEEKVLEIKNRLQTATREERQKSEILMENLEMKLESSRDLSRDCVCIDMDAYFAAVEMRDNPALRTVPMAVGSSAMLSTSNYLARRFGVRAGMPGFISNKLCPSLTIVPGNYPKYTKVSRQFSQIFMEYDSDVGMMSLDEAFIDLTDYVASNTEKKTFKRHRFGGDCPCWLPRFDENENTLEDLKIEESICPKCEKSRKIYYDHVEFGTGREEAVREIRFRVEQLTGLTCSAGIASNFMLAKICSDLNKPNGQYVLENDKNAIMEFLKDLPIRKVGGIGRVCEAQLKAMDIQTVGDMNLKKNLYPLCFTPLSQESFLRTALGLPGRPSESDPRRKSISVERTFSPTSDFNILLEEHQEICRMLEEDVRKSGIVGGKTVTLKLKLSSFDVLTRSLTPSDVVKSLEDIQKFSLELLEKEKGKEIRLLGVRLSQLIFEEDEKKRSKTITEFWNEKKLQIQNLQGSENVDDDDVIMMDTRPCPICGTDVENRLDVMNCHVDECILKVQNDDGPELICVSVENKSTQKPERPSTKKRKLQEKRPKAKKMVTIDSFWKKSG
What is the function of this protein?
DNA polymerase specifically involved in DNA repair.  Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls.  Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts.  Lacks 3'-5' proofreading exonuclease activity.  Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity (By similarity).
What are the official names of this protein?
DNA polymerase kappa.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATA_BACC2
Sequence: MSLFDHSVSELHKKLNNKEISVTDLVEESYKRIADVEDNVKAFLTLDEENARAKAKELDAKIGAEDNGLLFGMPIGVKDNIVTNGLRTTCASKMLANFDPIYDATVVQKLKAADTITIGKLNMDEFAMGSSNENSGFYATKNPWNLDYVPGGSSGGSAAAVAAGEVLFSLGSDTGGSIRQPAAYCGVVGLKPTYGRVSRYGLVAFASSLDQIGPITRTVEDNAYLLQAISGIDRMDATSANVEVGNYLAGLTGDVKGLRIAVPKEYLGEGVGEEARESVLAALKVLEGMGATWEEVSLPHSKYALATYYLLSSSEASANLSRFDGVRYGVRSDNVNNLLDLYKNTRSEGFGDEVKRRIMLGTFALSSGYYDAYYKKAQQVRTLIKNDFENVFANYDVIIGPTTPTPAFKVGEKVDDPMTMYANDILTIPVNLAGVPAISVPCGFGANNMPLGLQIIGKHFDEATIYRVAHAFEQATDYHTKKASL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: UBCP1_PONAB
Sequence: MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKGLLKLTQYLKEIAKLDDFLGLNHKYWERYLSKKQGQ
What is the function of this protein?
Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity.  Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1.  Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly.  Has also been reported to stimulate the proteolytic activity of the 26S proteasome.
What are the official names of this protein?
Ubiquitin-like domain-containing CTD phosphatase 1, Nuclear proteasome inhibitor UBLCP1.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with nuclear proteasomes.
Protein: TPD52_HUMAN
Sequence: MDCREMDLYEDYQSPFDFDAGVNKSYLYLSPSGNSSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQESL
What are the official names of this protein?
Tumor protein D52, Protein N8.
What is the protein family that this protein belongs to?
Belongs to the TPD52 family.
Protein: CDKAL_DANRE
Sequence: MMALVCDTAVDDIEDMVRITDVTPLQRQAARKSVVPRARKHKQETGEQMQTDSVIPGMQKVWLKTWGCSHNSSDGEYMAGQLAVAGYQITEDSSDADLWLLNSCTVKSPAEDHFRNAIRKAQEQNKKVVLAGCVPQAQPRMDYIKDLSIIGVQQIDRVVEVVDEAIKGHSVRLLGQKKEKGKRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGDLASYPVEELVERVRQSFQEGVCEIWLTSEDTGAYGRDIGSDLPTLLWRLVEEIPEGAMLRLGMTNPPYILEHLEEMSRILQHPRVFSFLHVPLQSASDSVLMEMRREYCCADFTHLVDYLKERVPGITIATDIICGFPGETDEDFEQTLALVRRYRFPSLFINQFYPRPGTPAALMQQLPAHVKKQRTKELSALFHSYRPYDHKMGEQQQVLVTEESFDSQYYVAHNKFYEQVLVPKRPEYLGKMVQVEVYECGKHYMKGRPLEEAPLRTAYTTAPLLKGQVSGHTQAGVCEPQCWMPDGMRILAVVLLLSAVLLALLMEKLL
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Threonylcarbamoyladenosine tRNA methylthiotransferase, CDK5 regulatory subunit-associated protein 1-like 1, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CYSP7_DICDI
Sequence: MKVLSALCVLLVSVATAKQQLSEVEYRNAFTNWMIAHQRHYSSEEFNGRYNIFKANMDYVNEWNTKGSETVLGLNVFADISNEEYRATYLGTPFDASSLEMTESDKIFDASAQVDWRTQGAVTPIKNQGQCGGCWSFSTTGATEGAQYLANGKKNLVSLSEQNLIDCSGSYGNNGCEGGLMTLAFEYIINNKGIDTESSYPYTAEDGKKCKFNPKNVAAQLSSYVNVTSGSESDLAAKVTQGPTSVAIDASNQSFQLYVSGIYNEPACSSTQLDHGVLAVGFGTGSGSSGSHGGSQSQSAGSDSQSAGSESSQSESGSQSQSESGSQSQSQSGSQSFSGSLYSGSYSGSQSGSQSGNSGAAVKQTGAGSGSGSGSGSGSGSGSGSVSGSASGSASGSASGSSSGSNSNGGVYPTAGDYWIVKNSWGTSWGMDGYILMTKGNNNQCGIATMASRPTAVASL
What are the official names of this protein?
Cysteine proteinase 7, Proteinase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: DIM1_KLULA
Sequence: MGKAVKKKYSGASSGGKEVDAEKHLTTVFKFNTDLGQHILKNPLVAQGIVDKAQIKPSDIVLEIGPGTGNLTVRILEQARKVVAVEFDPRMAAELTKRVHGTPVEKKLEILLGDFMKTELPYFDVCISNTPYQISSPLVFKLINQPKPPRVSILMFQREFAMRLLARPGDSLYCRLSANVQMWANVTHIMKVGKNNFRPPPKVESSVVRIEIKNPRPQVDFNEWDGLLRIVFVRKNRTIAAGFKSTTVLEILEKNYKAFLATQSAVPTTSSGDSLINEVKEKIEQVLSETGLAEKRAGKCDQTDFLKLLYGFHQVGIHFA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.
What are the official names of this protein?
Dimethyladenosine transferase, 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, 18S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: LEUD_STAA1
Sequence: MAAIKPITTYKGKIVPLFNDNIDTDQIIPKVHLKRISKSGFGPFAFDEWRYLPDGSDNPDFNPNKPQYKGASILITGDNFGCGSSREHAAWALKDYGFHIIIAGSFSDIFYMNCTKNAMLPIVLEKSAREHLAQYEEIEIDLPNQTVSSPDKRFHFEIDETWKNKLVNGLDDIAITLQYESLIEKYEKSL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PIF1_TRYB2
Sequence: MLRRLLQPAYNVALSGTSASTLPRKSASVGLVRTALMPVDYNAGALFCAMRFTSGTEKERKREPKRGSKRRSKATTTLSTPTDAQTSVTGAREGVALPQENMPDAIQPPATLEVRAAEVKEEPLAATPPQIQPQEETMGPIDGEPQLPLHSTLVYNALTGRMTSETSPSFLCLKSIGFGVNNKRQLYVEKPDVLRDLAQRMRKGTATLPSNWPVTIIRALGVILRNRRVEDPAEAIQQMMQVKINNLTHSRYAAVVNAVGDTDLQNILDGGLADEFVAVDLNEEQEKVINLALKGHLMYIGGSAGTGKTVLLRALCRRMQAEGLRVAMTATTGVAGCHIGGSTFHHAMGVSAQGDFVRKNHLLSYDAIIIDEVSMLPKKMFEEFDRVLREEAGAPDVPFGGVQIILCGDFLQLGVINEPPIIHSTTFREKFVKIRLETQVRQAKSSLFADALQQMRVGLVPESLTASVEQLPPGTMVPAAVNLLPTNKEVNTANEEELKRLPGDAVTLTPETGITALRCDTTATLLMRTTKDFKVEEFTKHLRGLLQATVDIPRASMVSAYRIYEDGHAVRVYLPQSESVAWRDAIRERFLEVAGLINDLDIGATVTEIIPSGDGLHTPEHEECLQRLMAKHPIAQPLTLKKGCRVLLRTNLTSRLVNGSIGTVVDFVECSMENIPVALRCERVNRCVDRYRIYCTMECGMPVPLLPVVKFHSGETIVVPPWEFLVGGNPITQYYSLSSVSLPLSLAYAFTVHKVQGLTLVGRVHLELSRMWPCEHLLYVAMSRVRNPEQLSMSSFDPKMVLANEACVKFDRELNTVDNLPSLAEYPVSSWKRCNDMVYHLRRQGTSLDRYLQNGAAKEGGSVPVQQLGLSGPVKGSLEHSMVVSRRLRKLIKQTERTIRMHERRQKKMAVEGAKQTDTTKASSGESLE
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of mitochondrial (kinetoplast) genome stability.  Essential for replication of kinetoplast minicircles.  Involved in the segregation of minicircle progeny.
What are the official names of this protein?
ATP-dependent DNA helicase PIF1, DNA repair and recombination helicase PIF1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PIF1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Note=Localizes to the antipodal sites flanking the kDNA disk.
Protein: MYO1E_HUMAN
Sequence: MGSKGVYQYHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPPGYHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI
What is the function of this protein?
Actin-based motor molecule with ATPase activity (PubMed:11940582, PubMed:36316095).  Unconventional myosins serve in intracellular movements.  Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments.  Binds to membranes containing anionic phospholipids via its tail domain.  Involved in clathrin-mediated endocytosis and intracellular movement of clathrin-coated vesicles (PubMed:36316095).  Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function.  In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.
What are the official names of this protein?
Unconventional myosin-Ie, Myosin-Ic, Unconventional myosin 1E.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Cell junction. Note=Colocalizes with F-actin (By similarity). In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin- coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles.
Protein: ADRE_PENRW
Sequence: MTQAQNHIVPPGSKVLVTGANGYIASHIIKVLLDLGYLVQGTVRTPMPWLTEYFEKRYGSGRFELIVVSDFQQSDAFDESVKGVSGVIHVAQGLPSSTAAETVESATAYTVNGVVNLLKAASTKPTIKRVVLTSSIVAAGYPAGKGFKLDVDTWDKSLEQASKGGTTVPIYRACKVEGERQAWKWVEKNQPHFELNTVLPWLTLGKILHPNIGGSTMGYVSGLLKGDTTPFKFLPLPWFVDVEDTARLHAIALISPSVRSERLFAAATPFIWGDVIEILKRIQPNNARIPAAPVKEEPTIGDIVPAARAEKLLRETFGQRGWTPLEVSLEGGIARE
What is the function of this protein?
Ketoreductase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (Ref. 2).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Ref. 2).  DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (Ref. 2).  The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (Ref. 2).  The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (Ref. 2).  The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A.  The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D.  The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F.  The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C.  Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (Ref. 2).
What are the official names of this protein?
Ketoreductase adrE, Andrastin A biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: ARL2_BOVIN
Sequence: MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQNLLVEERLAGATLLIFANKQDLPGALSSNAIREALELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRIFMAD
What is the function of this protein?
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP).  GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit.  Regulates formation of new microtubules and centrosome integrity.  Prevents the TBCD-induced microtubule destruction.  Participates in association with TBCD, in the disassembly of the apical junction complexes.  Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly.  Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3.  Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine.  Required for normal progress through the cell cycle.
What are the official names of this protein?
ADP-ribosylation factor-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Mitochondrion. Note=The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules (By similarity). The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.
Protein: Y086_METMP
Sequence: MESFLTEIQINVLNLRKRGHTQDEIANIMGTSRANISMIEKRARENIEKARNTLSIYNDIIAPSKIKIDKGTDVFSIPKIIFSKSDQEEIHVNYSSLQIMEFVNQNAQRYIKNRMVVEPFVVTILQNGDIFVHDYEESEENEKMPKKEI
What is the function of this protein?
Putative transcriptional regulator.
What are the official names of this protein?
Putative transcriptional regulatory protein MMP0086.
What is the protein family that this protein belongs to?
Belongs to the Tfx family.
Protein: NUSB_PECCP
Sequence: MKPAARRRARECAVQALYSWQLSKNDIADVEHQFLSEQDVKDVDITYFRELLAGVATQAEKLDQLMAPFLSRQIEELGQVEKAILRLAMFELSKREDVPYKVAINEAIELAKVFGAEDSHKFVNGVLDKAAPSVRKGKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RL4_STRSV
Sequence: MANVKLFDQTGKEAGEVVLNDAVFGIEPNESVVFDVIISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGIVFGPTPRSYAYKLPRKVRRLALKSVYSEKVAENKFVAVDSLSFTAPKTAEFAKVLAALSIDTKVLVILEEGNEFAALSARNLPNVKVATATTASVLDIVNSDKLLVTQAAISKIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: EX7L_CLOK1
Sequence: MYIKTLTVSDINRYIKKTLDNDFILGNCSVKGEVSNFKFHSSGHMYFSLKDKFSKINCIMFKSSVEKLNFMPGDGMKVIVKGRISLYEKEGVYQLYCSEMKPDGMGELYLAFEKLKIELEKKGLFDISHKKKIPLYAKKIGVITSPTGAAVKDIINVTRRRNKKIELLIYPSLVQGTGASDNIIKGIETFNSMEDVELIIIARGGGSIEELWCFNDEKLAEAVYSSKKPIITGVGHEIDYTIVDFVSDMRAPTPSAAAEIGVFSLEEYVQKILNYKNKLYNSVKNTVNDKKNRLAFVKKTLEVNNPLTYIANEYENIDKIKESLNFKIKVIINGKKEKLGKINALLSAHNPLNILNKGYCIIEDEQKNVISSIEELNKKYKVDIIMKDGTSKVELIHYKK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS2B_METHJ
Sequence: MVRLVITYDIRKDKIRNKLFRLLERYGAWKQYSVFELEINPVHKVELFHSIADLIEDTDRVRIYDLCERCQGKITELGEVSPDKMQVVI
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: NDK_STAS1
Sequence: MERTFLMIKPDAVQRNLIGEIISRIERKGLKLVGGKFMTVPQSLAEEHYAEHTDKPFYKHLISFITSAPVFAMVVEGEDAVHVARHIIGKTNPSEATPGTIRGDLGLTVGRNIIHGSDSVESANKEINLWFKADELSEYSESRESWLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_METEP
Sequence: MTNPIHIVGGGLAGSEAAWQVAQGGRTVVLHEMRPVRATDAHHTDGLAELVCSNSFRSDDANGNAVGLLHQEMRSLDSLIMRTADAHQVPAGGALAVDREGFSRAVTAALEDHPNITILREEVAGLPPEDWGSTILATGPLTSPALAEAVGTLTGRESLAFFDAIAPIVHRDSIDMGKAWFQSRYDKAGPGGTGADYLNCPMDREQYEAFVAALIAGEKTAFKEWEASTPYFDGCLPIEVMAERGPETLRHGPMKPVGLTNPHNPTVKAYAIVQLRQDNALGTLFNMVGFQTKLRHAEQVRVFRTIPGLENAEFARLGGLHRNTYLDSPRLLDATLRLKARPQLRFAGQITGCEGYVESAAVGLMAGRYALAEAEGQTLAPLPPTTALGALIGHITGGHVEATEEAERNAPRSFQPMNVNFGLFPPLAQMPRNETGKRLRGPEKAALKKRALTDRARADLAAWMTGERLPHAAE
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIH_SALTY
Sequence: MKTFTDRWRQLEWDDIRLRINGKTAADVERALNAAHLSRDDLMALLSPAAADYLEPIAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKRKTLDEVDIQRECDAIRKLGFEHLLLVTGEHQAKVGMDYFRRHLPTIRRQFSSLQMEVQPLSQENYAELKTLGIDGVMVYQETYHEAIYAQHHLKGKKQDFFWRLETPDRLGRAGIDKIGLGALIGLSDNWRVDCYMVAEHLLWMQKHYWQSRYSVSFPRLRPCTGGVEPASVMDEKQLVQTICAFRLLAPEIELSLSTRESPWFRDHVIPLAINNVSAFSKTQPGGYADDHPELEQFSPHDARRPETVASALSAQGLQPVWKDWDSWLGRASQTR
What is the function of this protein?
Catalyzes the radical-mediated cleavage of tyrosine to 2-iminoacetate and 4-cresol.
What are the official names of this protein?
2-iminoacetate synthase, Dehydroglycine synthase, Tyrosine lyase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. ThiH family.
Protein: Y2357_METMA
Sequence: MKNFHVVLEAAWLVRDVKTADDAIGVAISEAGKRLNPKLDFVEVDVGTTSCPVCGEPFSSVFIAANTALVGLIFEMKVFDAESAEHAERIAKSVIGKSLRDVPLTVVEVTEFERSVEKGEQQQKGKANK
What are the official names of this protein?
UPF0212 protein MM_2357.
What is the protein family that this protein belongs to?
Belongs to the UPF0212 family.
Protein: ISPG_CLOAB
Sequence: MQRIETRKVKVGSVYVGGDSRVTVQSMTNTDTRDSKKTIEQIKKLEIAGCDIVRCAVPDFDAASSLSEITKNVKLPVVADIHFDYRLALEAIKNGVSALRINPGNIGSKERVELVAKSAKEKNIPIRIGVNSGSLEKDILNKYKRVCSEALVESALNHVKILEDVNFNDIVISIKSSNVQMMIDSYRLISKEVNYPLHLGVTEAGTIWRGTIKSSIGIGTLLSEGIGDTIRVSLTGDPVEEVKVGREILKTFGYLKSGVEFISCPTCGRTSIDLIKIANEVEKRLEKTNKSIKVAVMGCVVNGPGEAREADIGIAGGKGEGLIFKKGEIIKKVKEENLVDELMREIDNM
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.