PharMolix/UniProtQA huggingface dataset:
Protein: PFKA_THENN
Sequence: MKKIAVLTSGGDAPGMNAAVRAVVRYGIKNGLEVIGVRRGYSGLIDGDFVKLEYKDVAGITEKGGTILRTSRCEEFKTEEGREAAAKQLKKHGIEGLVVIGGEGSLTGAHLLHEEHNIPVVGIPATIDNDIGLTDMCIGVDTCLNTVMDAIQKLKDTASSHERAFIVEVMGRHSGYIALMAGLVTGAEAIIIPEIPVDYSQLADRILQERRRGKINSIIVVAEGAASAYTVARHLEYRIGYETRITILGHVQRGGSPTAFDRRLALSMGVEAVEALLDGEADVMIALQGNKFVRVPIMEALSTKKTIDKKLYEIAHLLS
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALX4_HUMAN
Sequence: MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDAKSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT
What is the function of this protein?
Transcription factor involved in skull and limb development.  Plays an essential role in craniofacial development, skin and hair follicle development.
What are the official names of this protein?
Homeobox protein aristaless-like 4.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
Protein: RLMH_LACGA
Sequence: MNIKIVCVGKLKEKYFKDGIAEYVKRMGRFAKVKIIQVPDEKAPEKLSPAEMEQVKEIEGKRILDKIKDKEYVYVTAIKGKERTSEDFAKELADLTTYGHSDITFVIGGSLGTSNAVNKRADDLISFGKFTMPHQLMRLVLVEQIYRAFMINSGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y698_SHESR
Sequence: MLIEIPNVFSKEEVNQLREELDARTWIDGNQTSGVMASTRKRNQQLDKDDPVVLRIGELIMARLLAHPLFVSAALPLQFYPPLFNRYQGGETFGYHIDNAIRSTSDGMVRTDLSATLFLSEPDTYQGGELVIQDTYGQQSIKLAAGSLVLYPSTSLHQVTPVTSGERTAAFMWLQSMVRDEGQRRLLFQLDQSIQALTAQAAPERELFNLTGVYHNLLRRWSEL
What are the official names of this protein?
PKHD-type hydroxylase Shewmr7_0698.
Protein: RECX_STRCO
Sequence: MEPSAEDGGATSSSRAEKGEPPRDPVEQARAICLRLLTGTPRTRRQLAEALRKREIPEEAAEEVLSRFEEVGLINDGAFAQAWVESRHHGRGLARRALARELRTKGVEAALIDVAVSQLDTEQEEETARDLVARKLRATRGLDRDKRLRRLAGMLARKGYSEGMALRVVRQALEEEGEDTEHLGDEGF
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTRK1_CHICK
Sequence: WGCLRLPLPLCHALAAHCRCPASHTLRCREPLTVSSLSALLLGAHRPTDVIIENQALLTSLTRDDTRMLWDLRHLTISNSGLQYISDDAFQDNHRLSHVNLSFNALTSLSWKTFQHLPLQELTLEGNPFNCSCGIRWLQLWQNGSRAELGNQSLLCWEGSMLVALDSHPLHDCEPPTARIEHPDVVLRQGDSVNLTCHIWGEPSATGEWVLPHVGSEPSVTKLSEWELVLEINNISSSLNHKDLTCRAENSVGLAEDSVMLNVTFPPVILLLSEAIPQHFWCIPFSVDSNPTPRILWLFNGSMLPEGPYIHTRIVEYEPNSTVLHGCLQLNRPTHVNNGNYTLVVQNPLGRAARSIQGRFMDNPFSFSPEEPIPVSISPLGTRNSSLEGPVETADEHTFGVSVAVALAVFASLFLSVMLIALNKCGHRSKFGINRSAVLAPEDGLAMSLHFMTLGSSPVSSTESKLDGLKSNFIENPQYFCNACVHHVQRRDIVLKWELGEGAFGKVFLAECSHLLPEQEKTLVAVKALKEVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGDPLIMVFEYMKHGDLNRFLRSHGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYLASLHFVHRDLATRNCLVGHDLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDIWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRTCPSEVYDIMQSCWQREPQQRSIQDIHSRLQALVKTPPIYLDILG
What is the function of this protein?
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons.  High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3.  Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation.  Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signaling cascades driving cell survival and differentiation.  In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors.
What are the official names of this protein?
High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, Trk-A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Recycling endosome membrane; Single-pass type I membrane protein. Note=Internalized to endosomes upon binding of NGF or NTF3 and further transported to the cell body via a retrograde axonal transport. Localized at cell membrane and early endosomes before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation. Colocalized with RAPGEF2 at late endosomes.
Protein: FRSA_ECOLI
Sequence: MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEDDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITDWIEKRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters (PubMed:15808744).  Displays esterase activity toward pNP-butyrate (PubMed:15808744).  May stimulate mixed-acid fermentation by acting as a fermentation/respiration switch that down-regulates respiration and up-regulates fermentation rates (PubMed:15169777).
What are the official names of this protein?
Esterase FrsA, Fermentation/respiration switch protein.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: PTR32_ARATH
Sequence: MENPPDQTESKETLQQPITRRRTKGGLLTMPFIIANEGFEKVASYGLLQNMILYLMSDYRLGLVKGQTVLFMWVAATNFMPLVGAFLSDSYLGRFLTIVIASLSSLLGMVVLWLTAMLPQVKPSPCVATAGTNCSSATSSQLALLYTAFALISIGSGGIRPCSLAFGADQLDNKENPKNERVLESFFGWYYASSSVAVLIAFTVIVYIQDHLGWKIGFGIPAILMLLAGFLFVFASPLYVKRDVSKSLFTGLAQVVAAAYVKRNLTLPDHHDSRDCYYRLKDSELKAPSDKLRFLNKACAISNRDEDLGSDGLALNQWRLCTTDQVEKLKALVKVIPVWSTGIMMSINVSQNSFQLLQAKSMDRRLSSNSTFQIPAGSFGMFTIIALISWVVLYDRAILPLASKIRGRPVRVNVKIRMGLGLFISFLAMAVSATVEHYRRKTAISQGLANDANSTVSISAMWLVPQYVLHGLAEALTGIGQTEFFYTEFPKSMSSIAASLFGLGMAVANILASVILNAVKNSSKQGNVSWIEDNINKGHYDYYYWVLAILSFVNVIYYVVCSWSYGPTVDQVRNDKVNGMRKEEEEVIKLN
What is the function of this protein?
Low-affinity nitrate transporter involved in xylem-to-phloem transfer for redistributing nitrate into developing leaves.  Not involved in dipeptides transport.
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 1.1, AtNPF1.1, Nitrate transporter 1.12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMI_YERP3
Sequence: MTVRLILAKGREKSLLRRHPWIFSGAVQRLEGDALSGETIDILDSQGKWLARAAYSPESQILARVWTFQQDEVIDCAFFIRRLQQAQNWRDWLAQRDGLNGYRLIAGESDGLPGITIDRFQNFLVLQLLSAGAEYQRETLVSALQHCYPECSIYDRSDVSVRKKEGLPLTQGLICGEMPPALLPISENGMQLFVDIQQGHKTGFYLDQRDSRLAARNYANGRRVLNCFSYTGAFAVAALMGNCQQVISVDTSQSVLDIAKQNIELNQLDLSKTEFVRDDVFQLLRSYRAQGEKFDLIIMDPPKFVENKSQLASACRGYKDINMLAIQLLRPGGILLSFSCSGLMPVDLFQKILADAALDAGHDIQFIEQFRQAADHPVIAAYPEGLYLKGFACRIM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMIE_BRASO
Sequence: MLHGDITSSNDTIGVAVVNYKMPRLHTKAEVLDNARKIADMIVGMKTGLPGMDLVIFPEYSTHGIMYDSKEMYETASTVPGDETEIFAEACRKAKVWGVFSLTGERHEEHPKKAPYNTLILMNDKGEIVQKYRKIMPWVPIEGWYPGNCTYVSEGPKGLKISLIICDDGNYPEIWRDCAMKGAELIVRCQGYMYPAKDQQVIMAKAMAWANNVYVAVANASGFDGVYSYFGHSAIIGFDGRTLGECGEEDYGVQYAQLSKSLIRDARKNGQSQNHLFKLLHRGYTGMINSGDGDRGVAACPYDFYAKWVADPEGTREMVESFTRSTVGTEECPIEGIPNKKVAHR
What is the function of this protein?
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
What are the official names of this protein?
Aliphatic amidase, Acylamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: XERS_STRSV
Sequence: MRRELLLERIDKLKATMPWYILEYYQSKLAVPYSFTTLYEYLKEYDRFFNWVLESGITDASHIAEIPLSVLENMSKKDMEAFILYLRERPLLNANTTQNGVSQTTINRTLSALSSLYKYLTEEVENEQGEPYFYRNVMKKVATKKKKETLAARAENIKQKLFLGDETEEFLQYIDTEYPKKLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLKDINLKMMVIEVTRKGGKRDSVNVAAFAKPYLEEYLSIRIKRYKAEKTDTAFFLTEYRGIPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDKL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_SALNS
Sequence: MAKNYYDITLALSGICQSARLVQQLAHQGHCDADALHVSLNSVIDMNPSSTLGVFGGSEANLRLGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALNTLGDRINGLQRQLDHFDLQSDTLMSAMAGIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRASLLAGIRAAVLWHQVGGGRLQLMFSRHRLTTQAKQILAHLTPEL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EI3D2_DROAN
Sequence: MASYAPFIKPYVQYNEHGWGPCEIPDMDVPYQPFCKSDRLGKICDWTVAMQEKKFSNKYASSFGNNSQYAYFHEDDDSTFHLVDTSGSRALKPYQRGRFRPNVRNNARVKGRSGRGPGMLGVAGSMAGGGTTSGSTKYGKGRESRRNQGRRFARNAPSRLRESSVLVRPNWVSLEEIEFPRLLKLALPNIKEGQDIVTCGSLEYYDKLYDRINLRNERPLLKMDRIVHTVTTTDDPVIRRLSKTMGNVFATDEILATIMCCTRSNYSWDVVIEKLGTKVFLDKRDNAQFDLLTVNETSLEPPMDEEGSINSAHSLAMEATLINHNFGQQVLRVGEQEPRFKFGEPNPFEEPGVELACLGYRYRQWQLGNDLVLVARCKHNGVIQGPNGEVQFLSIKALNEWDSKAANSVEWRQKLDTQRGAVLASELRNNACKLARWTVEAVLAGSDQLKLGYVSRVTPRDHLRHVILGTQQFKPQEFATQINLNMDNAWGILRCLVDIVMKQPDGKYLIVKDPNKPMVRLYDIPENSFDSDAEDEENSSEPFANSLDN
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-2, eIF3d-2, Eukaryotic translation initiation factor 3 subunit 7-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_TRIRU
Sequence: MMFNNIISPLEQFEIKDLFSLNINIINLKMSLTNFGFYIIISTIIILTLHLLITYNNKLISNSWTLTKESIYATVHSVVINQINSKEGQNYFPFIYGLFIFILMNNLLGLIPYSFSSTSHFILTFFISFTVVLGATILGFQKHQLKFFSLFVPSGCPLGLLPLLVLIELISYLARNVSLGLRLSANILSGHMLLVILSDFTFKIMSSGIFYFLIGLIPLAFIFAFSGLELGIAFIQSQVFIVLTCSYIRDSLELH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RISB_STAS1
Sequence: MNFEGKLVGSDLKVAIVVSRFNDFITNRLLDGAKDTLIRHEVPEANIDVAYVPGAFEIPLVAKKLAKKNDYDAVITLGCVIRGSTSHYDYVCNEVAKGVSKANDVTDTPVIFGILTTENIEQAVERAGTKAGNKGAEAAVSAIEMANLLREI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SND1_MOUSE
Sequence: MASSAQSSGSSGGPAVPTVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDGKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKASKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPGHHLVTVMLSGIKCPTFRRETDGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNLLGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVPPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPRLEGDNIQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLHMDGANLSVLLVEQALSKVHFTAERSAYYKPLLSAEEAAKQRKEKVWAHYEERPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDISSHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTRVLPAQATEYAFAFIQVPQDEDARTDAVDSVVRDIQNTQCLLNVEHLSASCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR
What is the function of this protein?
Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (By similarity).  As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (By similarity).  Functions as a bridging factor between STAT6 and the basal transcription factor (By similarity).  Plays a role in PIM1 regulation of MYB activity (By similarity).  Functions as a transcriptional coactivator for STAT5 (PubMed:12819296).
What are the official names of this protein?
Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, p100 co-activator.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Melanosome. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus.
Protein: YL460_YEAST
Sequence: MQVAIPETMKAVVIEDGKAVVKEGIPIPELEEGFVLIKTLAVAGNPTDWAHIDYKIGPQGSILGCDAAGQIVKLGPAVNPKDFSIGDYIYGFIHGSSVRFPSNGAFAEYSAISTVVAYKSPNELKFLGEDVLPAGPVRSLEGVATIPVSLTTAGLVLTYNLGLDLKWEPSTPQRKGPILLWGGATAVGQSLIQLANKLNGFTKIIVVASRKHEKLLKEYGADELFDYHDIDVVEQIKHKYNNISYLVDCVANQDTLQQVYKCAADKQDATIVELKNLTEENVKKENRRQNVTIDIIRLYSIGGHEVPFGNITLPADSEARKAAIKFIKFINPKINDGQIRHIPVRVYKNGLCDVPHILKDIKYGKNSGEKLVAVLN
What are the official names of this protein?
Uncharacterized protein YLR460C.
What is the protein family that this protein belongs to?
Belongs to the YCR102c/YLR460c/YNL134c family.
Protein: MUTS_STRP8
Sequence: MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTSVRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSPCVDKLVNDIDSLPELEYLIRTAIDTDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTTSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFNDNHMITIQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLIRLETQSRSTEIISVPSKVEPSSAAREGQLSLFPDEDKSQEIIHTLEAIDVMNMTPLQAMTTLYELKKLL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: HEM6_PSEFS
Sequence: MTTRTEAVKAYLLDLQDRICSALETFETDTRFIEDAWTRPAGGGGRTRVIENGSVIEKGGVNFSHVFGSGLPPSASAHRPELAGRGFEALGVSLVIHPHNPHVPTSHANVRFFIAEKEGEEPVWWFGGGFDLTPYYGNEEDCIHWHRVAEQACAPFGPDVYSRYKAWCDTYFHIKHRNEPRGIGGLFFDDLNEWDFDTCFAFIRAIGDAYIDAYLPIVQRRKAMAYTEQQRQFQEFRRGRYVEFNLVYDRGTLFGLQSGGRTESILMSLPPQVRWSYDWKAEVGSEEARLTDYFLQDRDWLGLTAPKAAV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_AROAE
Sequence: MSYLQDDKPVTLFEIGKMRAEGRKISMLTCYDASFASLLERAGVDILLVGDSLGNVVQGQKSTLPVTLEHMIYHTECVVRGSTRPFIVTDMPFGAYHESPSQAMHNAASLLAAGAQMVKLEGGTFMAETVRFLVERGIPVCAHIGLTPQSVHQLGGYRVQGRSEAAAAQLKGDALALEQAGAALMVMEMVPAALAREVTASLASMATIGIGAGPDCDGQVLVLHDMIGVYPGKKARFVRNFMTGKTDIDEAVASYVQAVRDGSFPAAEHCY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_CHLFF
Sequence: MPKMKSNKSVAARFKLTGSGQLKRTRPGKRHKLSKKSSQEKRNLSKQPLVDKGQVGMYKRMMLV
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TXA22_ANDAU
Sequence: MMKLMLFSIIVILFSLIGSIHGADVPGNYPLDSSDDTYLCAPLGENPSCIQICRKHGVKYGYCYAFQCWCEYLEDKNVKI
What is the function of this protein?
Weakly inhibits the vertebrate potassium channel Kv1. 1/KCNA1.
What are the official names of this protein?
Beta-toxin KAaH2, Peptide AaF1CA22.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily. Sodium/Potassium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGH2_VIBPA
Sequence: MKWLSKSWAVAVVLLVGCAGRQEFIPPQPNAEEYAPPKLDYTLPDAQSGSLYRHQYTMTLFQDRRAYRVGDVLTVVLSEETSSSKKAGTKFGKSSAVNFAAPTIGTKKFDELGVSIDGSRNFDGSASSSQGNKLQGAITVTVHDVLPNGVLRISGEKWLRLNQGDEFIRLTGIVRVDDITRNNQVSSQRIADARITYAGRGALADSNAAGWLTQFFNSPWVPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein 2, Basal body L-ring protein 2.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: NU4LM_NOTTY
Sequence: MTAIYLNLTMAFSLALMGVLVYRSHLMSTLLCLEGMMLSLFILMTLLITHYRMSSISMLPLTLLVFSACEAAIGLALLVKMFTSYGNDHVQNLNLLKC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MATK_NUPAD
Sequence: MEKLQYELQGYLEIDRYRKQRFLYPLLFREYIYALAHDHGLNSSIFYEPTENLGYDNDNKSSSLIVKRLITRLHQQNHLIISVNDSRFVGPNRSFYSQTISEGFAGIMEIPFSMRLVPSLERIAKYQNLRSIHSIFPFLEDKLSHLYYVSDILIPHPIHLEILLQTLRTRIRDAPSLHLLRCFLHEHHNWNSLITPKKSTSIFSKENQRLFLFLYNSHVYECESVLVFLRKQSSHLRSISSLAFLERTHFYGKIKHLVVAPRNDSQRTLPLWFFKEPLMHYVRYQGKSIMASRCTNLLMKKWKYYLVNFWQCHFHLWSQPGGIHINELSNHSFYFLGYLSGVRLMPWVIRSQMLENSFMIDTAIKRFDTIVPIFPLIGSLVKAKFCNVSGYPISKSVWADSSDSDIIARFGWICRNLSHYHSGSSKKHSLCRIKYILRLSCARTLARKHKSTVRVICKRLGSKLLEEFLTEEQEIVSFIFRGTRLRSERIWYLDIIRINGLVPHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ILVD_CLOK1
Sequence: MRSDVITKGTKSAPQRALLNALGLTKEEIERPLVGIVSSKNDIVPGHMNLDKIVEAVKTGVSMAGGTPIVFPAIAVCDGIAMGHQGMKYSLVTRDLIADSTEAMAMAHAFDALVMVPNCDKNVPGLLMAAARLNIPTIFVSGGPMLAGKVDGCKVSFSSISEAVGAFNGGKITEEKLEEFESKVCPTCGSCSGMYTANSMNCLTEVLGMALGGNGTIPAVYSDRIKLAKHAGMKIMELLERNIRPRDVMTEAAFKNALTMDMALGCSTNSMLHLPAIAHEAGIELNVDMANEISAKTPNLCHLAPAGHNYVEELNEAGGIYAVMNEINKLNLLSTDLITCTGKTVAENIKGCINKNKEVIRPVENPYSTTGGIAILKGNLAPDSCVVKRSAVAPEMLKHEGPARVFDCEEDALNAINTGKIVAGDVVIIRYEGPKGGPGMREMLNPTSAIMGRGLGGSVALITDGRFSGATRGAAIGHVSPEAAVGGNIALVEEGDIIKIDIEANSIDFEISEEELERRRSNWKPRQPKITTGYLARYASMVTSGNRGAILEIPKF
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.