PharMolix/UniProtQA huggingface dataset:
Protein: YLPM1_MOUSE
Sequence: MYPNWGRYGGSSHYPPPPVPPPPPPVALPEASPGPGYSSSTAPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMIHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPSSAQPYLPPAQPGPSKPQLPPPPSIPSGNKTAIQQEPLESGAKNKTAEQKQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGLVTAKDVPEPIKEEAPGPAASQVAEPLAAEKPPLPPPNEEAPPPLSPEEPQSEDSEDSEDSEEDARFKQLKAIAAHWQAAAAHWQQQQQQRVGFQYQGIMQRHTQLQQILQQYQQVIQHSPHIQTMSLDVQLRHYEMQQQQFQHLFQDWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQTYLQEKVNSFQTVKSQYLGNMAMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPTSIPPPGMPPPVMPPSLPTSVPPPGMPPSLSSGPPPVLPPPALSSAGSPPVLPPPALPGGPPILPLPPLSSATPPPGIPPPGAPQGMPPQLTAPLPPASGSQNSQIPEKPRQALLPTPVSFGSTPPSPYHPPPQSEQVNSKPLNKVFSSEQGLGESSALSQSIIAAKDTPVKSGGLLADPPKGSFLEGPRGPREQKEQLQKLKDFGSEPQMADHLPPPDSRLQNPSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSIPMTRPPVPIPPPPPPPPPPPPPPPVIKSKTSSVKQERWDEDSFFGLWDTNDDQGLNSEFKRDTATIPSAPVLPPPPVHSSIPPPGPMPMGMPPMSKPPPVQHTVDYGHGRDMPTNKVEQIPYGERITLRPDPLPERSTFDADHAGQRDRYDRDRDREPYFDRPSNITDHRDFKRDRETHRDRDRDRVLDYERDRFDRERRPRDDRNQSYRDKKDHSSSRRGGFDRPSYDRKSDRPPYEGPPMFGGERRTYPEERMPLPAPALGHQPPPVPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFIAEVEKEEKDPDSGKKVKKKVMEYEYEADMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMAEHWEVAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEDQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYETRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAERALNRTKYI
What is the function of this protein?
Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation.
What are the official names of this protein?
YLP motif-containing protein 1, Nuclear protein ZAP3.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Migrates to nucleolar caps upon blockage of transcription.
Protein: CLPB_STRAL
Sequence: MDAELTNRSRDALNAATTRAVSAGNPDLTPAHLLLALLEGQDNENLVDLLAAVERRPGGGSARAPSASLGSLPGVTGSTVAPPQPNRDLLAVIADAGRRAKDLGDEFLSTEHLLIGIRPTARPPRCSPGRAPTPEKLLEAFQNTRGGRRVTTPRPEGQYKALEKFGTDFTAAARERKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKDKRLVSLDLGAMVAGAKYRGEFEERLKTVLSEIKESDGQIVTFIDELHTVVGAGAADSAMDAGNMLKPMLARGELRMVGATTLDEYRERIEKDPALERRFQQVLVAEPSVEDSIAILRGLKGRYEAHHKVQIADSALVAAATLSDRYITSRFLPDKAIDLVDEAASRLRMEIDSSPLEIDELQRSVDRLKMEELALDRETDPASRQRLEKLRRDLADRERSCAAHRPWEKEKQSLNRVGELKERLDELRGQAERAQQHGDFDTASKLLYGEIPTLERDLRWRPAEEEAAKDTMVKEEVGPDDIADVVGSWTGIPAGRLLEGETQKLLRMEAELGRRLIGQSEAVQAVSDAVRTRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMIRIDMSEYGEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEVEKAHPGVFDILLQVLDDGRLTDGQGRTVDFRNTILVLTSNLGSQYLVGSAPEEEKRRQVMEVVRSSFKPEFLNRLDDLVIFSALDEDELARIAGLQIAGLARRLADRRLSLDVTPEALAWLAKEGFDPAYGARPLRRLIQTAIGDRLAKEILAGEVRDGDTVRVDRVEDGLLVGRAEG
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRA_WOLSU
Sequence: METTMTRRDFLKSAGAAGAAGLVWSQTIPGTLGALEKQEIKGSAKFVPSICEMCTSSCTIEARVEGDKGVFIRGNPKDKSRGGKVCARGGSGFNQLYDPQRLVKPIMRVGERGEGKWKEVSWDEAYTFIAKKLDEIKQKHGAHTVAFTARSGWNKTWFHHLAQAYGSPNIFGHESTCPLAYNMAGRDVFGGSMNRDFAKAKYIINMGHNVFEGIVISYVRQYMEAIENGAKVVTLEPRLSVMAQKASEWHAIKPGHDLPFVLGFMHTLIFENLYDKKFVQKYCTGFEELKASIEPCTPEKMALECDIPADTIKRLAREFAKAAPKAIFDFGHRVTFTPQELELRRAMMMVNALVGNIERDGGMYFGKNASFYNQFLGEEDPKAKGLKKPKTPAYPKVEVPRIDRIGEKDGEFFLANKGEGIVSLVPKATLNELPGVPCKIHGWFIVRNNPVMTQTNADTVIKALKSMDLVVCVDIQVSDTAWFADVVLPDTTYLERDEEFTAGGGKNPSFGIGRQKVVEPLGDAKPGWKIAKELSEKMGLGEYFPWKDIEDYRLQQVDGDLDLLAKLKKDGSASFGVPLMLQEKKSVAEFVKKFPGAASKVNEEGLIDFPKKIQLFSPKLEEVSGKGGLGYEPFKYKEEDELYFVQGKTPVRSNSHTGNVPWLNNLMEYDAIWIHPKTASKLGIKNGDAIELYNKFSSQKSKALITEGVREDTLFGYFGFGHVSKDLKRAYGKGVNSNALMPSFTSPNSGMDLHVFGVKVKKA
What is the function of this protein?
Component of the phosphorylative electron transport system with polysulfide as the terminal acceptor.
What are the official names of this protein?
Polysulfide reductase chain A, Sulfur reductase chain A.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
Protein: TSAC_BUCBP
Sequence: MNILSLSECVDRLRKNLVIAYPTESVLGLGCNPESIDAVKVLLKLKKRKLNKGFILVASHFNQIRSYISESKLSIYHKKILYSSWPDTITYLLPAKSFVPDWLTGRSNFLGIRISAHNGINKLCSAFGKAIISTSANISGRNPCRTYEEFLKQFGTTVPILCGPLGTRKNPSKILNIINGSLIRHG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1782_PSEA6
Sequence: MAFDKKLLEIVACPVCKGTLILNKDSNGNERLVCRFDRLAYPIEQNIPVLLETEALVLSSEELEKIK
What are the official names of this protein?
UPF0434 protein Patl_1782.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PYRB_METFK
Sequence: MHNPQLTKDGKLKHLLTTEGLPRAILNQILDTAESFVGVAEREVKKVPLLRGKTVCNIFFENSTRTRTTFEIAAKRLSADVITLNVSTSSQSKGETILDTIDNLTAMHADMFVVRHAESGAAHFIARHVAPHIHVINAGDGRHAHPTQGLLDVFTIRRYKPDMHNLRVAVVGDVLHSRVARSEIHALTTLGVPEVRVIAPKTLLPQHVEKLGVHVYHDMREGLKDIDVVMMLRLQNERMNGSLLPSAQEYFKCYGLTPEKLAFAKPDAIVMHPGPMNRGVEIDSAVADGKQSVILPQVTYGIAVRMAVMSILAGNSE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PYRE_THISH
Sequence: MKTYQSEFLAFCLERGVLRFGEFTLKSGRISPYFFNAGLFNTGSDLARLGRFYAQAISESGAAFDMLFGPAYKGIPLAAATAIALAEHHGRDLPWCFNRKEAKDHGEGGSLVGAPLTGRVLIVDDVITAGTAIRESVDIIRAAGAEPVGVAIALNRQERGKGEHSAIQEVEAEYGLKVINIASLGDLIEFMREQGGLDEHLKAVEAYRAQYGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RS10_ALIF1
Sequence: MQNQRIRIRLKAFDYKLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLTSPHVNKDARDQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NU3C_THEVB
Sequence: MVAIPRLRDTATVFVLSGYEYFLGFLIICSLVPVLALAASALLRPKSGRMIRLTTYESGMEPIGGAWIQFNVRYYMFALVFVIFDVETVFLYPWAVAFHQLGLLAFIEALIFIAILVVALVYAWRKRALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.
Protein: GCH1_MOUSE
Sequence: MEKPRGVRCTNGFSERELPRPGASPPAEKSRPPEAKGAQPADAWKAGRHRSEEENQVNLPKLAAAYSSILLSLGEDPQRQGLLKTPWRAATAMQYFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGRVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS
What is the function of this protein?
May positively regulate nitric oxide synthesis in endothelial cells.  May be involved in dopamine synthesis.  May modify pain sensitivity and persistence.
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LPXB_SHIF8
Sequence: MTDQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEIEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNGARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: Y1271_PROMA
Sequence: MDYLTHKLLDPTRAKSCIQSIQRDQSLWKDGKSTAGLYASKVKNNLQLDKKSKVSIDNSNLIIKAIISDLLVKSFTIPRKVHGVMFSKSSKGNSYGMHLDNAYMSTGRSDLSFTLFLSDPGEYEGGELAIETIQETRKIKLPQGHIIIYPSTTLHSVEEVTSGTRIVCVGWIQSYIPNNEDRKILFSLDAGAKGLLAAHGQSHELDLVFQSYNNLLRRLGG
What are the official names of this protein?
PKHD-type hydroxylase Pro_1271.
Protein: LACR_STAAW
Sequence: MNKHERLDEIAKLVNKKGTIRTNEIVEGLNVSDMTVRRDLIELENKGILTKIHGGARSNSTFQYKEISHKEKHTRQIAEKRFIAKKAASLIEDGDTLFFGPGTTVELLAEEVNHHTLTIITNCLPVYKILLEKQTAHFRVYLIGGEMRHITEAFVGEMANAMLEKLRFSKMFFSSNAVNKGAVMTSTLDEAYTQQLALSNSIEKYLLIDHTKVGKEDFTSFCQLNELTAVVMDYEDEEKVETIKTYIEVVD
What is the function of this protein?
Repressor of the lactose catabolism operon.  Galactose-6-phosphate is the inducer (By similarity).
What are the official names of this protein?
Lactose phosphotransferase system repressor.
Protein: G6PI_AGRRK
Sequence: MNALVDQLKSTAAASKATDIRAAFAADPKRFSRFSASFDDLLMDYSKTAVNDEILTLLEKLATEGGVAAKREEMFSGVAINFTEDRAVLHTALRNRSNTPVLVDGKDVMPDVNGVLAAMGKFADGIRSGTLKGATGKAITDVINIGIGGSDLGPVMATLALAPFHDGPRSYFVSNIDGAHIADILKLVSPETTLFIIASKTFTTIETMTNAQTARNFIAKALGEAAVQHHFAAVSTALDKVAAFGIDSARVFGFWDWVGGRYSIWSAIGLPLMIAVGPENFGKFLDGAHAMDNHFRKAPFKENLPMLLGLIGFYHRNVLGYTTRAILPYDQRLSRFPAYLQQLDMESNGKGVTIDGTPVEGNSGPVVWGEPGTNGQHAFYQLIHQGTSIIPAEFMIAANGFEPDLRHQHELLIANCLAQSEALMKGRTFEEAKAQLTSKGMDDKKADFIAPHRVFTGNRPSITFVYDKLTPFALGRLIALYEHRVFVEGVLFRINSFDQWGVELGKELATGLLPVVEGKESAAGHDSSTQGLVAALSKLEK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPH1L_SCHPO
Sequence: MSKRNPPVTNIADLVSDSSLDEDSLSFLEELQDPELYFKNDTFSSKSSHSDGTVTGDTLRRQSSGATALERLVSHPRTKNFDLQGNGGQNSALKEVNTPAYQSMHHFEHLITPLPSTNASHSEVSLSAGVNDLNSNSEHDLLPKSVNKTPGSLSISRRRRIGRIGLGPPKRAEYTLTDPSKTSDTKNSTEADEDIEMKSREVSPASNSVAATTLKPLQLHNTPLQTSQEHPKPSFHPSQFESSFSPRVQFDHDVERRASELHSRPVTVFQEPQRSASQPYESHALSPKVAPLFDNSQATPIPKRQQDVVTVANLQFIKLGVVGKGGSSMVYRIFSPDNSRLYALKEVNFINADQTTIQGYKNEIALLRKLSGNDRIIKLYAAEVNDTLGQLNMVMECGETDLANLLMKNMKKPINLNFIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVEGNLKLIDFGIAKAIGNDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPFAHLKMIQAIAAIPNEQYHIHFPEVALPANAVQEKEGSLPGVTVGPDLMDVMKRCLERDQRKRLTIPELLVHPFLNPLPSYLTPLAKKPLPVSGHTNNAHPLRLSTEISASQLSMIIERSVELSKHKRLNKELIDSMAYDCVSNLRKMPE
What is the function of this protein?
Involved in the regulation of the onset of mitosis.  Involved in a pathway that coordinates cell proliferation and differentiation.
What are the official names of this protein?
Serine/threonine-protein kinase mph1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ATPF1_HUMAN
Sequence: MAAVVVAAAGGAGPAVLQVAGLYRGLCAVRSRALGLGLVSPAQLRVFPVRPGSGRPEGGADSSGVGAEAELQANPFYDRYRDKIQLLRRSDPAAFESRLEKRSEFRKQPVGHSRQGDFIKCVEQKTDALGKQSVNRGFTKDKTLSSIFNIEMVKEKTAEEIKQIWQQYFAAKDTVYAVIPAEKFDLIWNRAQSCPTFLCALPRREGYEFFVGQWTGTELHFTALINIQTRGEAAASQLILYHYPELKEEKGIVLMTAEMDSTFLNVAEAQCIANQVQLFYATDRKETYGLVETFNLRPNEFKYMSVIAELEQSGLGAELKCAQNQNKT
What is the function of this protein?
May play an essential role for the assembly of the mitochondrial F1-F0 complex.
What are the official names of this protein?
ATP synthase mitochondrial F1 complex assembly factor 1, ATP11 homolog.
What is the protein family that this protein belongs to?
Belongs to the ATP11 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYA_SULIK
Sequence: MKASEEEYRLNFFIKNDFKRKICKSCKTPFWTRDEKKEYCSDIPCTDYYFFDINIKSQPLTVKEAREKFLSFFEKRGHTRISPKPVLARWRDDLYLTIASIVDFQPHVTSGLVPPPANPLVVSQPSIRLEDIDNVGITFGRHLTTFEMAAHHAFNYPDHYVYWKDETTAYATEFFTKELGIPEEELNFKESWWEGGGNAGPCLEVTVGGLELATLVFMQYKITDNGNYTPLKLKIVDTGYGVERIAWITQKTPSAFHAIYGNLVYKFFNKIGVAYIDETLLKVASRFAGKIDPDNPDTIKIHRQMVSKELGIDIKAVEEELDRAAKVFQILDHTKTIMLMLADGLVPSNSGEGYLGRLVIRRALKVLRLLKSDVRLYELVKEQIDFWKEDFPQVLKNKDYILDAVELEQQRFEKILEKVPSIASTLARKSEITTEDLIQVYDSNGIPPDLLEEELKKKSVKFELPRNFYALVAKRHQTSTIKSVYDKVKLPKDMLEYITALQPTEKLYYKDQYMRSFEGKVLGVYKNYLILDKTTFYPEGGGQLGDTGLIIDEKSSKRYEVIDTQKVNDVIVHILKEEPSTIKVGDNVRGEINWERRYRLMRHHTVTHVILAAAKKVLGEHVWQAGAEKTPEKGRLDITHHKTLTEEEVKLIENYANSVISDRRPVKPLEMNRMEAEMKYGVSIYEGGVPNSATIRLLEIKDWDIESCGGTHVSNTSEIGAVKIINVERIQDGVIRLEYVAGPALVDYIRETEAKIVEASKIIGSSPDQLTSRLRRLLNEIEEKNNLIIQYRRIIETELLNNLKPYEINGNKIYIIEGLGDEEENKEILRKLTSTDNTIAISISDNRLQIATSKNMRVDKIVEELLKGGGKGGGKGTFANVILNSKKSKEEIIEIVRKSL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3166_POLNA
Sequence: MLFLLSPAKSLDYATPAHVAAHTQPLFKRQSAELIAVLKAKSPQEISSLMKLSDALAGLNVARYEAWSPAFTAHNSKQAVLAFNGDVYAGLDAKTLGEAQLAWAQDHLCILSGLYGVLRPLDWMQPYRLEMGTALVTGRGKNLYQFWGAQIADYLNERAATDVSPVIVNLASEEYFKSVSRKVLKARVVTCVFEEWRGDKYKIISFMAKRARGLMVRYAIENRLATVEKLKGFEAEGYCFDASASAVDRLVFRRGQGA
What are the official names of this protein?
UPF0246 protein Pnap_3166.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RCNA_ECOL5
Sequence: MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIAIKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIISTAFWMFWRTWRGERNWLENMHEHDHEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHANDIKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSLGLALTLVTVSVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR
What is the function of this protein?
Efflux system for nickel and cobalt.
What are the official names of this protein?
Nickel/cobalt efflux system RcnA.
What is the protein family that this protein belongs to?
Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMH_RICPU
Sequence: MIQSHVSVMLNKMLEALSPKAGESYLDCTFGAGGYSKAILESCNCYVTALDRDPNVIKRAEEIQQNYGERFDFVETNFAGSFAKLKEKKFDGIVLDLGVSSMQLDIADRGFSFLHDGPLDMRMSGQGLSAEEFVNAAEAKELADVIYKYGDESFSRRIAKRIVEYRKTARIDSTGKLAEIVRSSIGFRKGKIDPATKTFQAIRIYVNDELGELEQFLVNVKNILKKDGRLVVVSFHSLEDRIVKNFFKENSEKPVVRSKYAKDDMTIDPNKWLKIITNKALAPSDKEVGLNIRARSAKLRAAKAIYE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOM_PIG
Sequence: MFHQIWAALLYLYGILLNSIYQCPEHSQLTTGGVDGKEFPEPHLGQWYFIAGAAPTKEELATFDPVDNIVFNMAAGSVPMQLQLRATIRTKNGLCVPRKWIYRLSEGNTDLRTEGRPDMKTKLFSSTCPGGIMLKETGQGYQRFLLYNRSPHPPEKCVEEFQSLTSCLDFKAFLLTPRNQEACELSSN
What is the function of this protein?
Probably involved in lipid transport.  Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity).
What are the official names of this protein?
Apolipoprotein M, Apo-M, ApoM.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
What are the subcellular locations of this protein?
Secreted.
Protein: HBG_ALOSE
Sequence: MSNFTAEDKAAITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGSLSSPSAIMGNPKVKAHGVKVLTSLGEAIKNLDDLKGTFGSLSELHCDKLHVDPENFRLPGNVLVTVLAILHGKEFTPEVQASWQKMVAGVASALASRYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma, Gamma-globin, Hemoglobin gamma chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SYI_FERNB
Sequence: MDYKETLNLPQTNFQMKANLVQKEPNMLKYWEEKEIYKKTLETREGAPTYLLHDGPPYANGDIHLGTAMNKILKDFVTRYKTMRGYRVPYVPGWDTHGLPIEHRVTTTLGEEAKKKSPVEIRKLCKEFALKYVDIQREEFKRLGVKGDWEHPYITLTPDYEYHILDVFKTLVENGNVYRGNKPVYWCPTCRTALAEAEIEYHDHESPSIYVKFQMVDQPDTYVVIWTTTPWTIPANVAIALHPEYEYLKIKVGNEYWIVADGLLQKFASETGIEFQVTEKFLGKTLEGKLTKHPLYDRTSVIVLADYVTLEDGTGCVHTAPGHGEEDYQTGLKYNLPILSPVDDEGKFTKEAGKYEGLKIWDANKVVVEDLEKAGALIKFGKISHSYPHCWRCKGPVMFRATPQWFISVNKNNLRGKVLEQIKKVKWYPSWGENRITAMVQERPDWTISRQRVWGVPIPAVKCKSCDEVTLDPKVIEHFANIVKEKGTDAWFELDIKELIPSDFSCPKCGSKEFEKTYDTLDVWIDSGCSWEAVIRSKGEKFPVDLYLEGDDQHRGWFQSSIFLATAKTGNAPFKTVVTHGFIKDEQGRKMSKSLGNVIDPMEIVNKYGADILRLWVASTDFFDNIRVGKNIIEQQVEVYRKLRNTLRYLLSNLYDFTENDILPYEKLLPLDKWALGRLQKYIEQVTQYYEEFEYSKVYNATVKYCTTELSSIYLDILKDRLYVEAKDSIYRRSAQTVLYYILEALIKILAPIMPFTAEEAYQESPLKKYESVHLENWPEVRKEFINENLLEEFQQLLLVRDDVLKALENARSSDVIGHSLDAHVKIEPKNSEIGQLLEKYADMLEDFFIVSKVSILNELSDGINGQLVTVLVEHAEGQKCQRCWKYHPDTGKDENHPETCPRCSAVLRGERK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA2_ORYSJ
Sequence: MGDSQYSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKAANGVVIATEKKLPSILVDETSVQKIQSLTPNIGVVYSGMGPDFRVLVRKSRKQAQQYYRLYKETIPVTQLVRETAAVMQEFTQSGGVRPFGVSLLIAGYDDNGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELDDAIHTAILTLKEGYEGQISANNIEIGIIRSDREFKVLSPAEIKDFLEEVE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-2, 20S proteasome alpha subunit B, 20S proteasome subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HPF_STAAB
Sequence: MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
What is the function of this protein?
Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
What are the official names of this protein?
Ribosome hibernation promotion factor, HPF.
What is the protein family that this protein belongs to?
Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOS1_ARATH
Sequence: MAFSSCFLLVLLQIFSALLLCLAQDQSGFISLDCGSPRETSFREKTTNITYISDANFINTGVGGSIKQGYRTQFQQQTWNLRSFPQGIRNCYTLNLTIGDEYLIRANFLHGGYDDKPSTQFELYLGPNLWSTVTTTNETEASIFEMIHILTTDRLQICLVKTGNATPFISALELRKLMNTTYLTRQGSLQTFIRADVGATVNQGYRYGIDVFDRVWTPYNFGNWSQISTNQSVNINNDYQPPEIAMVTASVPTDPDAAMNISLVGVERTVQFYVFMHFAEIQELKSNDTREFNIMYNNKHIYGPFRPLNFTTSSVFTPTEVVADANGQYIFSLQRTGNSTLPPLLNAMEIYSVNLLPQQETDRKEVDAMMNIKSAYGVNKIDWEGDPCVPLDYKWSGVNCTYVDNETPKIISLDLSTSGLTGEILEFISDLTSLEVLDLSNNSLTGSVPEFLANMETLKLINLSGNELNGSIPATLLDKERRGSITLSIEGNTGLCSSTSCATTKKKKKNTVIAPVAASLVSVFLIGAGIVTFLILKRKKRTKLGLNPNSGTGTTPLHSRSHHGFEPPVIAKNRKLTYIDVVKITNNFERVLGRGGFGVVYYGVLNNEPVAVKMLTESTALGYKQFKAEVELLLRVHHKDLTCLVGYCEEGDKMSLIYEFMANGDLKEHLSGKRGPSILTWEGRLRIAAESAQGLEYLHNGCKPQIVHRDIKTTNILLNEKFQAKLADFGLSRSFPLGTETHVSTIVAGTPGYLDPEYYRTNWLTEKSDVFSFGVVLLELVTNQPVIDMKREKSHIAEWVGLMLSRGDINSIVDPKLQGDFDPNTIWKVVETAMTCLNPSSSRRPTMTQVVMDLKECLNMEMARNMGSRMTDSTNDSSIELSMNFTTELNPGAR
What is the function of this protein?
Regulates negatively the abscisic acid (ABA) signaling pathway (PubMed:25274985).  Required for full susceptibility to filamentous (hemi)biotrophic oomycetes (e. g.  H. arabidopsidis and P. parasitica) and fungal (e. g.  E. cruciferarum) pathogens, probably by triggering the repression of ABA-sensitive COLD REGULATED and RESISTANCE TO DESICCATION genes during infection, but independently of immune responses (PubMed:21711359, PubMed:25274985).  Involved in BAK1-dependent and BAK1-independent microbe-associated molecular patterns (MAMPs)-triggered immunity (PTI) leading to defense responses, including callose deposition and MAPK cascade activation, toward pathogenic bacteria (e. g.  P. syringae).  Required for chitin-mediated PTI (PubMed:27317676).
What are the official names of this protein?
LRR receptor-like serine/threonine-protein kinase IOS1, Protein IMPAIRED OOMYCETE SUSCEPTIBILITY 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.