PharMolix/UniProtQA huggingface dataset:
Protein: RHAD_LISMF
Sequence: MTKDIMDAVFIKEMAKTTSNLYRLGWDERNGGNITYLLDEKEVVEYLDVKQIIRTIPMDFDGKKLAGKYFLVTGSGKYFKNVEEAPAVNLGVIQVSEDGKAVHLLWGYTDSGLPTSELPAHFMSHIARLSVDPENRVVMHCHATHLLAMTFTHELTEREFTRTLWQMCTECLVVFPEGVGIIPWLVPGTNEIGEATSEKMKENRLIVWPHHGIYGAGKSMDETFGLIETAEKAAEVYTIVMSQGGIKQAITDEQLKALGERFGVEAKAGYLIN
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD1_METJA
Sequence: MPLNMNKYLTDAYTGGIIKKYPEDFIVEEITPEGIILEVGKSIEFKDEENWKGNYIHFTLEKRNWTTLDAIREIANRVGKQRKHFGFAGNKDKYAVTTQRVGCFNVKLEDLMKVKIKGIILRDFQKTNRKIRLGDLWGNRFTIRVREPELKGKELEEALNKLCKLKYFLNYYGVQRFGTTRPITHIVGRFIIERDWEGAFHAYCGTPLPYDDKKSKLARELVDEENFKEAYKKFPKAFFYERRMIKAYIETGSYQKAFMILPPYLRCMFINAYQSYLFNEIINRRFEYGFEPMEGDILIDNVPSGALFGYKTRFASGIQGEIEREIYERENLSPEDFKIGEFGSFIGDRRAMIGKIYNMKYWIEDDSYVLQFCLKKGNYATSVLREFIEKKD
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D 1, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D 1, tRNA-uridine isomerase D 1.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RF1_HAMD5
Sequence: MKPSFIKKLEALQERHEELQAHLADPLTIQDQERFRMMSREYAQLSNIAELFTEWLKLQNDMIAAKSLLQDPEMHEMATEELEKAKIQSEQLTQQLQILLLPKDIDDSRSCFLEIRAGTGGDEAAIFAGDLFRMYARYAESRSWKMEIISAHEGEHGGYKEMITKISGEGVYGQLKFESGGHRVQRVPTTESQGRIHTSACTVAVMPEIPEEELPKITLSDLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKAMSVLGARMHAAQVQKRQQAQASERRNLLGSGDRSDRHRTYNFPQGRVTDHRINLTLYRLDEVMSGKLDILIHPLLREHQADLLSALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKNK_BOVIN
Sequence: MRSTLLFAVILALSSARSLGAVCEESQEQVVPGGGHSKKDSNLYQLPPSLLRRLYDSRVVSLDGLLKMLSKASVGPKESPLPQKRDMHDFFVGLMGKRNLQPDTPVDINQENIPSFGTFKYPPSVE
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.  Is a critical central regulator of gonadal function (By similarity).
What are the official names of this protein?
Tachykinin-3.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COAT_BPLLH
Sequence: MTVVLDSKDLARIDEEYKADSQVWSYLTGGNGVTQRFRGHNEVRINKLSGFVDATAYKRGQDNARKTISVGKETVKLTHEDWFGYDLDQFDMDENGAYTVENVVREHNKMITIPHRDKVAVQKLFDSAAKKATDSITKDNALDAYDTAEAYMFDNEVPGGFVMFVSSAYYTALKQSAAVTRTFSTDGTMVINGIDRRVAQLDGGVPIVRVSSDRLKGLGITNHVNFILTPLSAIAPIVKYDSVSVIDPSTDRSGNRWTIKGLSYYDAIVLDNAKKGIYVAATAGV
What are the official names of this protein?
Major capsid protein, ORF3 protein, Protein Gp34.
What is the protein family that this protein belongs to?
Belongs to the Lactobacillus delbrueckii bacteriophages Gp34 family.
What are the subcellular locations of this protein?
Virion.
Protein: SEC65_YARLI
Sequence: MAILEEIDDVDNMDFDPAEFDPRAVLTDATAHQESDGRGPINLISKAEHERREQAKKQQEQQQEQQQQANPMAQLQQMMDQMNQGGGMPPNMGQQGKPGTQVFDSEEFKNQEIQESDFKDWQIVYPVYFDKNKTVGEGRRVPLELAVENPLGQTIAEACKMLTLPSIYEAHKTHPKDWANPGRVRVQLKDDPALGLPPHSVKNKRHLFRLIAQYMKEHPTKEVTPYQGPVFQKIIQTNPEFPWNSKNLPPKPQYPRGWKMPEILPILSPALSHGEANNDMMEQMANQFMPKIPEAPPQQKVKKMKVRVGR
What is the function of this protein?
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane.  It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).
What are the official names of this protein?
Signal recognition particle SEC65 subunit.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_SALCH
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLVEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RIMP_PROM0
Sequence: MNKENKSKLEKLLENVANKQDLEIYSLNIQTNQNPIVIEIIIKKTNGNDVSLDDCALFNTPASDEIEKSNLLNCSYVLEISSQGVSDELTSERDFKTFKGFPVNVELNQKNSKIKFLNGLLYEKSNDYLAINIKGRIKKIPFDEVLKISLCTLKD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_BUCAK
Sequence: MAKQSMKAREVKRVKLADKFFAKRAELKAIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNPCRQTGRPHGYVGKFGLSRIKLREAAMRGEVPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: DCTA_SALPK
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHYYPELGAQMKPLGDAFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAQAVAVYAAQAKEQGIIAFLMDVIPGSVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLVQLGQLIICFYITCILFVVVVLGTIARVTGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIFHQITLLVVLLLSSKGVAGVTGSGFIVLAATISAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATVVVAKWVKELDHQKLDDVLNNRAPDGKTHEISSYSRHLCP
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADB_PYRHO
Sequence: MMEMRVGIVGGGLAGLTAAIALAEKGFDVSIIGPRSTDSNSYLAQAGIALPLLEGDSIRIHVLDTIKAGKYINDEEIVWNVISKSSEAHDFLTSHGVTFTGNELEGGHSYPRIFTIKSETGKHIIPILEKHARELDVNFIRGFVEEIGINNGKLAGVFLQGELLKFDAVVIAAGGFSGLYRFTAGVKNNIGLLIGDVALKGVPLRDMEFVQFHPTGFIGKRTYLITEAVRGAGAKLVTGDGERFVNELETRDIVARAIYMKMLEGKGVFLDARGIENFKDRFPYIYSVLRGEGINPEKDLIPITPVAHYTIGGISVDAFYRTRIKGLYAIGESACNGFHGANRLASNSLLECVVSGLEVARTISREKPKREVNDAPYSFNELGDVDSIREVLWNHAGIVRDEWSLREGLRKLKEIEVDERLKLVAKAVIISALKREESRGAHYRKDYPFMRKEFEHSSFFYPNV
What is the function of this protein?
Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
What are the official names of this protein?
L-aspartate oxidase, LASPO, Quinolinate synthase B.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPG4_CAEEL
Sequence: MRLVYSLIFLLFIPFSHPNPIPIPTISPETTNAYLRAFLPWWPEKTDFTLRTAPTPEESEAEIVGNLLESSGEKENVTEFATEKEEIDPSTLRVHDLPPSPLDEFAPEGSPKSLVASGARSSDGNFIISFDEMGECPRDCSNDLRDALGIILQDMSHVERYRQICGKYTNAITCVNEDTRCNKEDRDMFETMTSGLNYMCVEQKLAFNATIKCIDDEAGVVQSECDTQCQTKNLFMNWMMKTAFQDTIQQGVNGIVGAATGTNANPLAFLQPVAGAAGGAPGGGWADMLANIGQRPPSPQDAQQGFENFRQFTNDLCRIGDCMLDCIRSKFNTRCEGSAGTLLSEVFVRPIAATQNKLSILRPILGTFMPEQCGYLTNNAELKKHRIDATMDEELKRMYAEKIAKEARDRTAQDEILANLVPLDENGVPLPRALPELKSIESPLDVSVKTLDQLILDMYSNNKTEELNISEKNNVTSTFSEPSEKEDEASTTVISVISPLHTNATDSEILEHISEKSTEESSGSSGEMSGDGSDNEASGEGSGEYDASGSSGDNSGEFNSSGSSGEASEEGESSGSEDQGSGNYKMIESIESSGEFSGSSGEGSGDTASSDTSIDDKSIIRSGEGSAESVSEILQEASGEDAPTLTPTSEESTGYKIDHSGFGESSGSSGESIELRDSGEGSAEYDASGSSGDNSGDFNSSGSSGEASGVGESSGSEDQGSGNYKKIEVIESSGDYEFSGSSNESIEQSKEGSAASIYEILQAASGEDTPTLTLLSEDSTGY
What are the official names of this protein?
Chondroitin proteoglycan 4.
Protein: THA_PIG
Sequence: MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLRGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEAGSLTSSDEDPEVCEDAAQATQPLPEAPPRADGEGGGGGS
What is the function of this protein?
Nuclear hormone receptor that can act as a repressor or activator of transcription.  High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
What are the official names of this protein?
Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1, c-erbA-1, c-erbA-alpha.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. SUBCELLULAR LOCATION: [Isoform Alpha-2]: Cytoplasm. Nucleus. Note=When overexpressed found in the cytoplasm where it colocalizes with TACC1.
Protein: CP131_DANRE
Sequence: MHTTRSPSASIQAGAAGDALDLSLNGSQLTMGRRPSSASPGKHFSRSISVSVAYDGRGKRNTLTDAGLGSSRAIKNLRRSNSTTQVNQQANTSLSSEGHTEDFLALFNSSSDGRRKLASLSKMSKDRTTWNILDDQPRVFPVPSSSHSTCSMDSPTGLKKREAGVSLAANFTANNRSNKAAVGNAVTAILHNNHSEKPLTPKSSNQKPSFNNLIKATVNDDVTLDVSGSLTKSQKNFSSASSSSNNNAPRSPRSPGQPRRREVTEEEAERYIQQVNHAAIIIQRWYRRHVNSKRANENIIKQLLASKKKEREQRAEEAKTTESLKKKEDDRKRIREEKARLARLTAIQELQQKRAQRAAEVQQIAEQETEALRHPGKVGRKKLTKSSPTSPTDIKAKNTDSNVNVVSDLDDVTNLRAASPAGSACRVSQCSQEILQRSVSMEDQRQGASSSRAQSKTTLNDLLDTLKLLEEEPERLSEPKSYRKDKYSWIDEDGDSNSLTTDNVERHRQLSQTPALPDGGALLSEAKLQSIMSFLDEMEKSEQERPRSVTSGSHREVVLSEEDLAVVEQASATAAEVTGSMMRLRLELDEKKRTVNMLQTALAQQRELTIRHVKETEKELNHTFQLQKEQYEATIQRHLTFIDQLIDDKKALSERCEEVVGELKQVDQKYTKKIAQMQEQHELVWQILGPMCEEIKKLKELMSATEKVRREKWINEKTKKIKEITVKGLEPEIQKLISKHKQELKKLRVLHEAELLQADERAAQRYVRQSEELRQQLEKEKDEQCQRERELAKQRFEKQLQEEENVLQQQRRRLYKEVSEEKERLTQLAARQHAELEDLRKQLEDNSSLAGRALREELEKSRDEQERRHQVEIKALKERLEIEKQTWEENYMKKEEAWLLSRERELKEEVRRGRDKEIELAIQRLEVETREAREECERAADNRMKRVREKYEAELRDLERSERTSLQKQQEMREKHSEMEAELLRLQSLLRQREQEISDLTQVTARDKLSEERRSLSEVIRQEFAERLIELEEENRRMKMEVSEAKARLRLEVERVTREKEEELAEVHQRVKSAILKKEETVNNLRKQHEAAVKRADHLESLLEQQRKQLLGK
What is the function of this protein?
Cilium-specific protein required for the regulation of cilium/flagellum formation (PubMed:19254375).  Involved in centriole duplication (By similarity).  May play a role in melanosome trafficking (PubMed:24550735).
What are the official names of this protein?
Centrosomal protein of 131 kDa, 5-azacytidine-induced protein 1.
What is the protein family that this protein belongs to?
Belongs to the CEP131 family.
What are the subcellular locations of this protein?
Chromosome, centromere. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein: YQGF_LATSS
Sequence: MRLMGFDVGSRTVGIAVSDLFGWTAQGVEIIRINEDESEFGLDRVKELVAQHQVTGFVLGLPKNMNNSIGPRAVKAQEYGAMLTELFPEIPVDYIDERLTTVQAERMLVEQADTSRKKRKQVIDKLAAVMILQNYLDAKGPLTKQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL198_YEAST
Sequence: MGYTLFRFIVPFNPYFSSFYPSFPFYLSFPFCPSFPSFLSFPSSIFSLSFPSFLHHHLLIFSSLRIPFPWFLPLLQLVYLCYKVPWLLEWLIHSSKLAYQCCRILIFAQLVSLVRNQKH
What are the official names of this protein?
Putative uncharacterized protein YLR198C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSD_RALSO
Sequence: MNNTYPHPIIAREGWPYLGGIFIVTLIVHAAAGLGWAWPFWLLTVFVLQFFRDPARTVPTQANAILSPADGRIVAVEQVRDPYADRDALKISVFMNVFNVHSNRAPVDGTVQQVQYFPGKFVNADLDKASLENERNAVVLRRADGQVVTSVQVAGLIARRILCYTKVGETLARGQRYGFIRFGSRVDVYLPLTARPRVTIGEKVSATLTVLAELD
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRUD_ECO45
Sequence: MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAEETELQTLLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIHFWLPAGSFATSVVRELINTTGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: MIC60_AJEDR
Sequence: MQVVRYYAVARKPNAGVRSSSTPNAAATPELSQKATNSTSTKPPGPNDPDVRSPASPSTGSTLHPETVSKPPQSPAVQGQTSPGSSVQPPEHEPSPPPPRPPPAPKTGLLRKLLYLFLTTGLAYAGGVWYSLRSDNFYDFFTEYIPYGEEAVLYLEERDFRSRFPSIARQINRRVSAPRDEGAQVMIPGRSGLSWKVAEEQQEASDVTKQGQHISATDANELTEETKVAEKAKEDVKSKPVAKKAEAAEPKSSPKVVEPHPAKAEENTSLEAPRQPVVPAAAAIEHLGLDNEDEPVVQDLVKVFNDIITVISADESASKFSVPIAKAKEELEKIGDRIVALKNDAQESAKEEIRNAQAALDKSAAELVRHINEVRAQDAAEFREEFESEREKISKSYQEKVTTELQRAHEVAEQRLRNELVEQAIELNRKFLADVKTLVENEREGRLSKLAELTANVAELERLTAGWSDVIDINLRTQQLQVAVDSVRTTLENSEVPRPFIRELAAVKELASNDEVVAAAIASISPTAYQRGIPSPAQLVDRFRRVASEVRKASLLPENAGITSHAASLVLSKVMLKKQGTPVGNDVESILTRTENLLEEGNFDEAAREMNSLQGWAKLLSKDWLADVRRVLEVKQALEVIETEARLRCLQVE
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: LOLD_PARXL
Sequence: MNDRSANLSMPSADTVPHPYVLEATGISKSFVQGGLNVTVLNNAQLSVRRGEKLAIVGASGSGKSTLLHVLGGLDDPSAGQVSVMGKPFTRLSERERNDLRNRALGFVYQFHHLLPEFSALDNVAMPLRIRRMSTEAARREALAVLERVGMGHRAKHRPGELSGGERQRVAIARALVTKPACVLADEPTGNLDGGTADTVFNLMLELSQTLETSFVIVTHDPELAGRCDRIMRLRDGVLHEEPPVPV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CYSN_VIBCH
Sequence: MNNAVKEQLAELGIEGYLNQHQHKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYEDQLAAVHNDSQRVGTTGSRPDLALLVDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYTRNMATGASTCDLAVILIDARKGVLDQTRRHSFISNLLGLKHFIVAVNKMDLVDYSQDRFEQIRAEYLEFSKHLQGETEIQIIPLSALEGDNVVEKSRLMDWYQGPSLLELLEYVDIDRDKSSGAFRFPVQYVNRPNLDFRGFAGTIASGVVKVGDKIKALPSGKTSTVTRIVTFDGDLPQAQAGLAVTLTLADEIDISRGDLIVLESAQVDSTNHLLADVVWMTEQPLQVGRDYDIKIAGKKTVGQVKAVRHQYDINNLSTYHAESLPLNGIGLCEWTFTQTVALDKYLDCADTGGFIIIDRLTNVTVGAGLVRDSLQNITGQTESFSAFELELNALVRKHFPHWQAIDLSRLGKA
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: RLMKL_SHEB5
Sequence: MLNFFAAAPKGFEYSLAQELTEFGATEVKESVAGVYFTASLTLAYRITLWTRLASRIVLVIYKGSCESAEQLYNAAYCVDWPAHFSNKSTFSIDFHGTGGFLNNTQFGALKIKDAIVDRFRDDDIERPNVSRVDAEFKVDAHFRNGVITIAMNFSGPSLHQRGYRSTTGEAPLKENLAANMLVRSGWQASPSTLLDPFCGSGTVLIEAALMAADIAPGLQRSRFGFEHWRRHDKAVWQEIVEEAKARASLGVKRCEIKFYGSDIDSRLVALAKRNAENAGVLELIEFNVADALTIAPPAESGYLITNPPYGERLGNVSELLQLYYQLGDKFKKEFGGWKVAMLCSDIELVSSLKLKADKQMKMFNGALECAFNIYTLHANSTRRDTPVLPDGVDIADIAPAFANRIKKNAKLLEKWAKKEGIDSYRIYDADIPEYNVAVDKYLDYVIIQEYMAPATIPEAVTKRRLSDVLLALPSAIGINPNKMIMKTRERQKGTSQYQKLDERKLELITTEYGAKFKLNLTGYLDTGLFLDHRLTRRLVGQKSKGRRVLNLFSYTGSASVHAALGGAKSVTTVDMSNTYIAWAKDNFALNGLQGKQYEFVQSDCMQWIRDCNEQYDLIFIDPPTFSNSKRMEDSFDVQRDHVNLLSSLVKLLSPTGELVFSNNKRKFKMDIETLTKMNINVTNIDDVTLPMDYKRNPHIHNTWLITHA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_DECAR
Sequence: MPDIKLPDGSIRSYEQAVTVAEVAASIGAGLARAALAGKIGGQLVDTSYLIEQNADLAIITERDAEGLELIRHSTAHLLAYAVKELFPEAQVTIGPVIENGFYYDFAYKRPFTPEDLVAIEKRMAELAKKDIPVSREVWARDDAVKFFLDLGEKYKAELIGAIPADQQVSLYREGDFIDLCRGPHVPTTAKLKVFKLMKVAGAYWRGDHRNEQLQRIYGTAWAKKEDLDAYLHMLEEAEKRDHRRLGKQYDLFHMQDEAPGLVFWHPKGWAIWQEIEGYMRAVYRNNGYQEVRCPQILDKSLWEKSGHWEHYKDNMFTTSSENRDYAVKPMNCPGHVQVFNAGLRSYRELPLRYGEFGSCHRNEPAGALHGLMRVRGFVQDDGHIFCTEDQIESEVTAFNALVKKVYADFGFNDVAVKLALRPDSRVGADDVWDRAEDALRQGLRASGLEWTELPGEGAFYGPKIEFHIRDAIGRSWQCGTMQVDFSMPGRLGAEYVGADDTRKVPVMLHRAILGSLERFIGILIENFAGALPLWLAPVQVVVLNISEKQADYAAEVAQKLHSAGFRAEADLRNEKITYKIREHSLNRLPYQLVVGDKEKADGLVAVRTRGGQDLGQMPVDVLIKRLQEEVVARSGTA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_PSECP
Sequence: MIDVKDLSENPDKFRASQRARGADESVVDAIISADSARRAALIRYENLRAEQNVFGKKVAQAKGEEKQALLAEVKELANSVKAASAEADAAQTKQEELLRTVPNLVEDGVPEGGEDDYVVVKTVGTPREFPDFEPKDHLEIGELIGAIDMERGAKVSGSRFYFLRGVGARLEMALLQMAMEQAIEAGFIPMITPTLVRPETMQGTGFDVKHDAEIYRLAEDDLYLVGTSEVALAGYHADEILDFSAGPIRYAGQSSCYRREAGSHGKDTRGIIRVHQFNKVEMFIYTTVEEAAAEHQRLLAWEEEMLAKCELPYRVIDTAAGDLGNSAARKYDCEAWVPTQGAYRELTSTSNCTTFQARRLNIRERAVNAEGVAKGTRAVATLNGTLATTRWIVALLEHHQNADGSVNVPKALQKYLGGLEVLPVL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_COREF
Sequence: MARLAGVDLPRNKRMEIALTYIYGIGPARAKQLLEETGVSPDLRTDNLTDEQIASLRDVIEATWKVEGDLRREVQADIRRKIEIGSYQGLRHRRGLPVRGQRTKTNARTRKGPKKTIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CSD_XYLFA
Sequence: MDRINTSAAPPTSPDWERLRTDFPLLQRHVHGKPLIYFDNANTAQKPQAVITATDTFYRRHNANISRAVHTLGTEATEAYEATRTALATLLNAPTHELVLCSGTTFAINLIAYSWALPRLRAGDVILVSRMEHHANIVPWQLIAERTGARIQVADILPNGTLDLDALHTLMTPQVKLLAITHVSNVLGTVNPIHDICRQARQRGITTVVDGSQAAPHRHIDIPAIGCDFYAITGHKLYGPTGTGALWARREHLHIMPPFLGGGEMIKEVSFDGTLFNTPPHKFEAGTPNIAGFIGLRAAVDYVRRIGIEQIETRETELLAHLTEELQKIDGMRLFGTAPNKAAVVSFMIEGTHAHDLATLLDLEGVAIRSGQHCAHPLLQYYGVTATCRASLAFYNTHEEIERFIAALLKVRKLLG
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: RRF_COPPD
Sequence: MKEHEITRQAREHFQKTINTMSDQLSTVRASRVSPAILEPVTVEYEGAKYKLSELAMVVAQDARTLIIEPWDVSMIPAISRSLQKANVGANPSDDGKRIKLVFPSLSQERREELARLVDKYLEEARIALRNIRREYIDEVKSKEKKKELSEDESRRIQNELQKAFEEYEKQMEQICQRKRKEIMEE
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.