PharMolix/UniProtQA huggingface dataset:
Protein: COXX_SYNR3
Sequence: MAEVPIAVPVSIRDEVVPSRKRVKLPPWLEIAKPRLIPLLLATTLGGMALSESWPLPLPRLACTLGGGALAAAAAGVLNCLWEEQLDGQMQRTSGRALPSGRLSGSQAFLIAVALACGASLLLVAGVNCLAAGLSLLGLCSYVLLYTIVLKPRTTRNIVIGGVAGAIPPLVGAAAATGHVGLGGWWLFGLVMLWTPAHFWALALLLTDDYRSVGIPMLPVVKGPEVTGRAINRYAYATVAASLLGVLTLPSGGLFYGLMVLPFNGRLLQMAQRLGELPDDKQRAKGLFRWSILYLFGICLLLLLARTTMAADFSNQLISLLTLPPASAF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HXC10_MACNE
Sequence: MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKRDEGGSPSLTLNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDNQTPSPSEIKTEQSLAGPKGSPSESEKERAKTADCSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C10.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YWCE_HALH5
Sequence: MDLFFAYMLVASATPLFLWLEHRKIALTSIPFIIIMWVLALSHMFEGFLFDLHHSVFLTAFFVNVIIAHFAALVLYAYPHIRPKSRTFTESMD
What is the function of this protein?
Required for proper spore morphogenesis.  Important for spore germination (By similarity).
What are the official names of this protein?
Spore morphogenesis and germination protein YwcE.
What is the protein family that this protein belongs to?
Belongs to the YwcE family.
Protein: NU4LM_URSAR
Sequence: MPVVYVNIFLAFIVSLMGLLVYRSHLMSSLLCLEGMMLSLFVMLTVTVLNNHFTLANMAPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TSAD_MYCA9
Sequence: MTVILAIESSCDETGVGIAELTPDGSVVLLADEVASSVEEHARFGGVVPEIASRAHLEALGVTARRALDLAGVQRPDVVAATIGPGLAGALLVGVSAAKGLALAWGVPFYGVNHLGGHIAADVYENGPLPECVALLVSGGHTSLLHVRSLAEPIEELGATVDDAAGEAYDKVARLLGLGYPGGKVLDELAQQGDSSAVPFPRGMTGPRDARHSFSFSGLKTAVARYLEKHGVEADFSPADVAAGFQEAVADVLTMKAVRAATDLGVSTLLIAGGVAANSRVRALAEQRCAETGLTLRVPPLRLCTDNGAMIASFAAHLVAAGAQPSSLQAAADPGLPVVKGQVH
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA3_MAIZE
Sequence: MGALPVAHSLALTAAFLPCRRPAAHGRCRRRRYRAVVAYMEPNPNSPAAIAGRLVGALPIVGLVARILNDEGGVGGDIIDFAEFRRRVSKKCTVMDSKAFYDFNQRRGKPGDPFYVLLCCWLAAIGAGLLKTEEILEGVARLRISNDIEFEEETFIDMMRAAKEKRAKLKAPAPQIPMETRAEKALEAIYVCCFGQDMVEDEDEKLLRAILNAVFPSVGRAAVERMVASMAKQVASGERKRDGRTVSKEVQQRQLKDLEFLKQNKLESS
What is the function of this protein?
Nuclear genome-encoded factor required for the accumulation of photosystem I (PSI).  Functions as PSI biogenesis factor.  Cooperates with PYG7 to promote the stable assembly of PSI in the thylakoid membrane.  May target primarily the PsaC subunit.  Does not seem to be required for the expression of chloroplast genes encoding PSI subunits.
What are the official names of this protein?
Photosystem I assembly factor PSA3, chloroplastic, Protein PHOTOSYSTEM I ASSEMBLY 3.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. Note=Associates with the stromal face of the thylakoid membrane.
Protein: RNH3_MYCGE
Sequence: MQHYKPADFYLIGSDESGKGDSFGGICVSAVLIEKKQLINLENLQVTDSKKLSDHTVKLLAKSIQTTVMDHHTITLDPKQYNDLTKSLKNTNLLLTNLHCQLYQKLLEKNQLLRQTVTISIDQFANQELFVNYLNKLTNFTDKTVLLPDQFLINGETKSLVIAAASILARDSFINQLQLLNQKVNYDLPKGSSHGIEQALLFLNQQRGFSQIEQFKQVAKLNFKNVTKFLQQLVY
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSH1_ORYSJ
Sequence: MQPPTGAVSGSSSSSLECVSSCRTSWRGGGRPYECSVLSCAWNAPRALTGALASTTAQCSSCSHAEAGAGWRRRGQSQRSNNSLLHITWAEGINRGKFGYGSSAHSFPTGNFFKSWSTSVDPTWRVFCYSSSESFNHISPETLWEDLKPAISYLQPEELNFVHDALKLAYEAHNGQKRRSGEPFIIHPVEVARILGEHELDWESIAAGLLHDTVEDTDMVTFERIENEFGVTVRRIVEGETKVSKLGKLQCKNEGNSKQDVKAEDLRQMFLAMTEEVRVIIVKLADRLHNMRTLTHMPQHKQYAIAMETLQVFAPLAKLLGMYRIKSELEYLSFMYMNPGDFAELKKRVEDLYKAHEQELEEANQILGEKIAEDQFLDLVSVETQVRSVCKELYSIYKTALKSKSSINEINQVAQLRIIIKPKSCNGVGPLCTAQQICYHVLGLVHGIWTPIPQAVKDYIATPKPNGYQSLHTTVIPFLNESMFHLEVQIRTEDMDLIAERGIAAHYSGRGVVSGPVRPGISSGRNSNGKVICLNNTGFALRIGWLNAIREWQEEFVGNMSSREFVDTITRDLLGSRVFVFTPKGEIKNLPKGATVVDYAYLIHTEIGNKMVAAKVNGNLVSPIHVLANAEVVEIIIYDKLSAKYAFQRHQQWLQHAKTRSARHKIMKFLREQAALSAAEITADAVNNFVADLEDESDYEQSIPSSENKDYTFNWQKILNSDKLSFGNKKSDCFLPVKNVSVPKVNGKHNKTVKELGIKINGSTFRGDSFTDFIHPGVSSSKEVLPSVDNWKAGKICAWHNTEGSSIQWLCIVCVDRKGMVAEVSSALTACGITICSCVAERDKRRGIGVMLFHFEGAYENVVSACSGVDMILGVLGWSVGCSCNPLGVLEC
What is the function of this protein?
May be involved in a rapid plant ppGpp (guanosine 3'-diphosphate 5'-diphosphate)-mediated response to pathogens and other stresses.
What are the official names of this protein?
Putative GTP diphosphokinase RSH1, chloroplastic, RelA/SpoT homolog 1, Os-RelA1, OsRSH1, ppGpp synthetase RSH1.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HS2ST_HUMAN
Sequence: MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMDGPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQDQVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATELYRTGKKSHLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN
What is the function of this protein?
Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS).  2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes.  Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity).
What are the official names of this protein?
Heparan sulfate 2-O-sulfotransferase 1, 2-O-sulfotransferase, 2OST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: NNRD_NATMM
Sequence: MGRLQRTLSNISEESDTDNGRVAVVGGSIEYPNQPALVGRAALRTGTDHVRTLVPEALYAPVAGSSPNLLVSPYDGDQFDQDAAADAVDICEWADALVIGPGLVDAEADAIRDVLERTDIPVVVDALAIEPALESDLSRAVLTPSGSEDGPIYEAYGSLRAFTEETGAVITLTGGVDVIVTTGERLENDTGTSALTVAGTGDTLAGITASLLGQEMDRQDAAELGAWILGKSGELATAEYGPGVVATDVIECIPKTIR
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ADP-dependent (S)-NAD(P)H-hydrate dehydratase, ADP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: CRR6_ARATH
Sequence: MATKAVLLPWLIPSPRHVSLFPVVQLPALETAGWCVRKRRAEDVAVSVAFNPSGNFDISAFENDQDSDKVEPPMPPTTGRYEVVIDNDSIGRLDLSPFQRAIGITSPDDFGVAEPKRYLDRTIGFTINYKREDPGDPRELSEYPDVRLWFVRLDAMYPWLPLLLDWRAGELARYAAMLVPHQMSLRMGVVFNPEALELFVMNKVFVVYPWLKRHGVPKPRLKTSDMARMLGFGIGDELFDLIDHNE
What is the function of this protein?
Required for both formation and activity of the chloroplast NAD(P)H dehydrogenase (NDH) complex of the photosynthetic electron transport chain.  May function in assembly or stabilization of the NDH complex (PubMed:16648216, PubMed:20444231).  Required for the accumulation of NDH subcomplex A, which is a core part of NDH.  May be involved in post-translational steps during the biogenesis of subcomplex A (PubMed:20444231).
What are the official names of this protein?
Protein CHLORORESPIRATORY REDUCTION 6, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Note=Previously localized in chloroplast thylakoid membrane fraction.
Protein: Y2470_DESHY
Sequence: MSGHSKWANIKHKKAKADAQKGKIFTKLGRELIVAARAGGGDPNNNFRLKIAIDNAKSANMPNDNIQRAIQKGVGGGEGESYEELRYEGYGPGGVAIMVDIMTDNRNRTAGEVRHIFSKHGGNLGETGCVNWMFTEKGQLMILKEDLKCDEDELMLLVLEAGAEDLQQDEESFVVYTAPGDMEAVRQALLDQGIAIEEAKINQVPQNTIEIADLEQAKKLVRMMELLEDHDDSQGVYANFEFADSIDEEELD
What are the official names of this protein?
Probable transcriptional regulatory protein DSY2470.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_LEPCP
Sequence: MKASELRAKDVAALEKEISDLLKAHFGLRMQKATQQLTNHSVIKQTRRDIARARTILTEKKKGAA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y1330_SODGM
Sequence: MLNDMPALTHEQQQLAVERIQALMAEGMSSGAAIAQVARELRAGYTGERVTLRWEEDTEVLETPAARAETDPYDSNPDDD
What are the official names of this protein?
UPF0181 protein SG1330.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: Y2351_NOSS1
Sequence: MTYCLRIADIPTNERPRERLMTHGPKVLATAELIAILLGTGQGPGKLSAVGLGQYLLQELGKNQRDPLAVLREVTPAELMQIPGIGPAKATSILAAVELGKRTFQFRPLDKTPIDSPVAAVAALSQDLMWQNQERFAVLLLDVKNRLLGTQVITIGTATETLASPREIFREIIRQGATRTIVAHNHPSGNVEPSPEDIELTRQLLAGAQLLGIPLLDHLILGNGNHQSLREITTLWNDYPQGD
What are the official names of this protein?
UPF0758 protein alr2351.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: DTX43_ARATH
Sequence: MTETGDDLATVKKPIPFLVIFKDLRHVFSRDTTGREILGIAFPAALALAADPIASLIDTAFVGRLGAVQLAAVGVSIAIFNQASRITIFPLVSLTTSFVAEEDTMEKMKEEANKANLVHAETILVQDSLEKGISSPTSNDTNQPQQPPAPDTKSNSGNKSNKKEKRTIRTASTAMILGLILGLVQAIFLIFSSKLLLGVMGVKPNSPMLSPAHKYLSIRALGAPALLLSLAMQGIFRGFKDTKTPLFATVVADVINIVLDPIFIFVLRLGIIGAAIAHVISQYFMTLILFVFLAKKVNLIPPNFGDLQFGRFLKNGLLLLARTIAVTFCQTLAAAMAARLGTTPMAAFQICLQVWLTSSLLNDGLAVAGQAILACSFAEKDYNKVTAVASRVLQMGFVLGLGLSVFVGLGLYFGAGVFSKDPAVIHLMAIGIPFIAATQPINSLAFVLDGVNFGASDFAYTAYSMVGVAAISIAAVIYMAKTNGFIGIWIALTIYMALRAITGIARMATGTGPWRFLRGRSSSSSS
What is the function of this protein?
Citrate transporter responsible for loading citrate into xylem tissues, which helps facilitate iron transport to shoots (PubMed:12172022, PubMed:15310833, PubMed:17351051, PubMed:18826429).  Mediates the citrate release in the apoplastic spaces during plant development allowing iron nutrition between symplastically disconnected tissues (PubMed:21742986).
What are the official names of this protein?
Protein DETOXIFICATION 43, AtDTX43, Multidrug and toxic compound extrusion protein 43, MATE protein 43, Protein FERRIC REDUCTASE DEFECTIVE 3, AtFRD3, Protein MANGANESE ACCUMULATOR 1.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_LISMC
Sequence: MARKTNTRKRRVKKNIESGIAHIRSTFNNTIVMITDTHGNALAWSSAGSLGFKGSRKSTPFAAQMAAESAAKSAQEHGLKTLEVTVKGPGSGREAAIRALQAAGLEVTAIKDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: ENO_LISIN
Sequence: MSIITEVYAREVLDSRGNPTVEVEVYTEAGAFGRALVPSGASTGEYEAVELRDGDKARYLGKGVLKAVENVNDIIADKIIGFDVTDQIGIDKAMIELDGTPNKGKLGANAILGVSLAAARAAADELGVHLYEYLGGVNGKVLPVPMMNILNGGEHADNNVDVQEFMVMPVGAPNFKEALRMGAEILHALKAVLKGKGLNTGVGDEGGFAPNLKSNEEALETIMQAIKDAGYKPGEEVKLAMDAASSEFYNRETGKYELKGEGVTRTSEEMVTWYEEMITKYPIISIEDGLDENDWDGFKLLTERIGDRVQLVGDDLFVTNTTKLKEGIEKGIANSILIKVNQIGTLTETLDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPTRTDRVAKYNQLLRIEDNLADLAEYHGNDTFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: DEOC_LACLA
Sequence: MQINKYIDHTILKADAPKSKVQQIIDEAKKYDFMSVCINPTWVSYASQELKDSDVKVCTVIGFPLGANTSELKAFEAKNAIENGADEIDMVINIGAAKSKDWNLVESDIAAVNAVKGDKLLKVIIETSLLTDDEKIKACQIAKAVGADFVKTSTGFSTGGATVHDVKLMRQTVGPDMGVKASGGVHNLEEAKAMIDAGATRLGVSAGVAIMEGLTSNDNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_SHIF8
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB1_NOSS1
Sequence: MSKLIPVIKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVRVEGRVEFFNQNIYERRVNLNRLRRQVSMVHPKPNLFPMSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLWDEIKHKIHKSALDLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLSQVSRVSDFTAFFKGNENRIGQLVEFGLTKKMFNSPHDSRTREYVLSRLG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YIA2_MYCTX
Sequence: MRKWVRQAQVDAGARPGTTTEESAEIKRLRRDNAELRRANAILKTASAFFAAELDRPAR
What are the official names of this protein?
Insertion element IS986 uncharacterized 6.6 kDa protein, ORFA2.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: GNAT3_HUMAN
Sequence: MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANTLEDGGMTPQLAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction.  Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter.  Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibody.  Gustducin heterotrimer transduces response to bitter and sweet compounds via regulation of phosphodiesterase for alpha subunit, as well as via activation of phospholipase C for beta and gamma subunits, with ultimate increase inositol trisphosphate and increase of intracellular Calcium.  GNAT3 can functionally couple to taste receptors to transmit intracellular signal: receptor heterodimer TAS1R2/TAS1R3 senses sweetness and TAS1R1/TAS1R3 transduces umami taste, whereas the T2R family GPCRs act as bitter sensors.  Functions also as lumenal sugar sensors in the gut to control the expression of the Na+-glucose transporter SGLT1 in response to dietaty sugar, as well as the secretion of Glucagon-like peptide-1, GLP-1 and glucose-dependent insulinotropic polypeptide, GIP.  Thus, may modulate the gut capacity to absorb sugars, with implications in malabsorption syndromes and diet-related disorders including diabetes and obesity.
What are the official names of this protein?
Guanine nucleotide-binding protein G(t) subunit alpha-3, Gustducin alpha-3 chain.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Dual distribution pattern; plasmalemmal pattern with apical region localization and cytosolic pattern with localization throughout the cytoplasm.
Protein: KCY2_BORBU
Sequence: MKIALSGKSGCGNTTVSGMIAKHYGLEFINYTFHDIAREHNIPFSEFYEKEIIGRNDYYWDKYLDNRLSVLSRKNNTVLASRLAIWISKSADLKIYLYAKMEVRAERIMTREGGMYSDVLSSTFIRDENDKKRYLAIYNIDIDDYFSETDLVIDVTNINPNEVFELIRDEIDKRNLKKNS
What are the official names of this protein?
Cytidylate kinase 2, CK 2, Cytidine monophosphate kinase 2, CMP kinase 2.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFF2_PONPY
Sequence: MDLFDFFRDWDLEQQCHYEQDRSALKKREWERRNQEVQQEEDLFSSGFDLFGEPYKTNKGDALANRVQNTLGNYDEMKDLLTNHSNQNHLVGIPKNSVPQNPNNKNEPSFFPEQKNRIIPPHQDNTHPSAPMPPPSVVILNSTLIHSNRKSKPEWSRDSHNPSTVLASQASGQPNKMQTLTQDQSQARLEDFFVYPAEQPQIGEVEESNPSAKEDSNPKSSGEDAFKEIFQSNSPEESEFAVQAPGSPLVASSLLAPSSGLSVQNFPPGLYCKTSMGQQKPTAYVRPMDGQDQAPDISPTLKPSIEFENSFGNLSFGTLLDGKPSAASSKTKLPKFTILQTSEVSLPSDPSCVEEILRESQHLTPGFTLQKWNDPTTRASTKMLEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVEKAKPRNNPVNPPLATPQPPPAVQASGGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQNKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNASQVPAEPKERPLLSLIREKARPRPTQKIPETKALKHKLSTTSETVSQRTIGKKQPKKVEKNTSIDEFTWPKPNITSSTPKEKESVELHDPPRGRNKATAHKPAPRKEPRPNIPLAPEKKKYRGPGKIVPKSREFIETDSSTSDSNTDQEETLQIKVLPPCIISGGNTAKSKEICGASLTLSTLMNSSGSNNNLSISNEEPTFSPIPVMQTEMLSPLRDHENLKNLWVKIDLDLLSRVPGHNSLHAAPAKPDHKETATKPKRQTAVTAVEKPAPKGKRKHKPTEVAEKIPEKKQRLEEATTICLLPPCISPAPPHKPPNTRENNSSRRANRRKEEKLFPPPLSPLPEDPPRRRNVSGNNGPFGQDKNIAMTGQITSTKPKRNEGKFCATFKGISVNEGDTPKKASSATMTITNTAVATATVTATAIVTTTVTATATATATTTTTTTTISTITSTITTGLMDSSHLEMTSWAALPLLSSSSTNVRRPKLTFDDSVHNADYYMQEAKKLKHKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMRLKNFASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVAQIPSPWVGNGKNTPSPVSLNNVSPINAMGNCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRENKEFFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL
What is the function of this protein?
RNA-binding protein.  Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure (By similarity).
What are the official names of this protein?
AF4/FMR2 family member 2.
What is the protein family that this protein belongs to?
Belongs to the AF4 family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: RSMH_PSEPK
Sequence: MTIDSGFNHITVLLDEAVEALALRADGCYLDGTFGRGGHSRLILSKLGPQGRLLGFDKDPQAIATGQALAAEDGRFVIVQRSFAELGAEVAARGLHGKVSGVLLDLGVSSPQLDDPERGFSFLNDGPLDMRMNPDQGVSAAEFIATAPVEEIARVFKEYGEERFAGRMARAVVERREKQPFTRTADLAEVLKVANPAWEKGKNPATRAFQGLRIHVNNELGDLEAGLEAALDALEVGGRLAVISFHSLEDRIVKLFMRKLVKGEADNLPRNLPVQHKVFEPKIKLIGKAQFASEAELKANPRSRSAVMRVAEKLR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_STAEQ
Sequence: MEEVLKLKIPASTANLGVGFDSIGMALDKYLHMSIRKIERANWEFLYYSSELEGLPKDENNYIYQTALNVARKYNVTLPSLQIEMRSDIPLARGLGSSASALVGALFIANYFGNIQLSKYELLQLATEIEGHPDNVAPTIYGGLIAGFYNPITKITDVARIEVPHVDIILTIPPYELRTEDSRRVLPDTFSHKGAVQNSAISNTMICALIQHKYKLAGKMMEQDGFHEPYRQHLIPEFNQVRKLSRQHDAYATVISGAGPTILTLCPKEKSGKLVRTLREKINNCASELVTINEIGVKDEVVYLKS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.