PharMolix/UniProtQA huggingface dataset:
Protein: AIM23_KLULA
Sequence: MKYHYIQMLRTTFKYSISSIRLFCNNRVLQNESRAVSDLLFNLPTYNPATHRKSGNNSPHKNRDKHRHRNGNKDQRNKKLVFRWNSGTEKQQAAANSVLEEILAINSKGNIKAINPETSKLEEANIRNFLKGVNLEINGIAMVSIDNAASGDVRLPIVKEVPTRQALKNYSDKLSKIKEEELIKLGVNIKKTGRRSPDSKADSSWKSIKVSWQISDYDLKKQKCSEIVSNLEKGSKIALFINDKDSSNLSPIDEEELEAMQESSISKKEMKRREEVLEKLNEIISEYSSQITQEGLINQRIIMKVTPNLVNTNNGVDKKALKEQRKRERQEKLQRRIEKKKTSDSTE
What are the official names of this protein?
Altered inheritance of mitochondria protein 23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYC6_THEVB
Sequence: MKKRFISVCAIAIALLVSLTPAALAADLANGAKVFSGNCAACHMGGGNVVMANKTLKKEALEQFGMYSEDAIIYQVQHGKNAMPAFAGRLTDEQIQDVAAYVLDQAAKGWAG
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: COAD_PARL1
Sequence: MARIGLYPGTFDPMTNGHLDIIRRGLKLVDHLIVAIGVNATKTPLLTLEERFQLIEQEAGPIAKELGSKISTASFSGLVVNAADEHGATVILRGLRGAVDFEYETQMVGMNRVMNPHVETVFLAASPDTQFISSTLVRQIAGMDGDISPFVPPHVKAKVLARVAEQKKSR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCTG_SHISO
Sequence: MIRHGSNKLKIFILSILLLTLSGCALKSSSNSEKEWHIVPVSKDYFSIPNDLLWSFNTTNKSINVYSKCISGKAVYSFNAGKFMGNFNVKEVDGCFMDAQKIAIDKLFSMLKDGVVLKGNKINDTILIEKDGEVKLKLIRGI
What is the function of this protein?
Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells.  Pilot protein that is required for the proper localization of the secretin MxiD/SctC in the outer membrane.  Also influences both MxiD/SctC multimerization and stability.
What are the official names of this protein?
Type 3 secretion system pilotin, Lipoprotein MxiM.
What is the protein family that this protein belongs to?
Belongs to the MxiM family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CPTP_XENTR
Sequence: MSSTEEKFSLKEVLVSFKSCLVDDDQDIIVEQYLNGWKGLVRFMNSLGTIFSFVSKDAVTKIQIMENYLAGTNGERYRTLQSMVEHELSSDLVDLTKRCNNPDSGCRTILRLHRALRWLQLFLEKLRTSNEDSKTSTLCTEAYNDSLANFHPWIIRKTATVAFLALPTRNTFFEVMNVGTTEEVVAMLGESMPYVTKVYDFTHEIYSQHNLLELP
What is the function of this protein?
Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane.  Required for normal structure of the Golgi stacks.  Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0).  Plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid.  Has no activity with galactosylceramide, lactosylceramide, sphingomyelin, phosphatidylcholine, phosphatidic acid and ceramide.  C1P transfer is stimulated by phosphatidylserine in C1P source vesicles.  Regulates autophagy and pyroptosis, but not apoptosis.
What are the official names of this protein?
Ceramide-1-phosphate transfer protein, Glycolipid transfer protein domain-containing protein 1, CPTP.
What is the protein family that this protein belongs to?
Belongs to the GLTP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein. Nucleus outer membrane; Peripheral membrane protein.
Protein: LON_KORVE
Sequence: MANEAHNIEHTDPEFRDDSADARTLPLLPVRDTVLFPHAVLPLTVGRESSVQLINSLGEDKTIVVVAQREARVDSPQPSDLFAIGSLAVVHKVVKMPNQSLFVFAEGLERVRVTEYVQLNPYMRATVETVPEAFPPKSAEIEALQRNVLTLFQQIVTGSPTLSDELSTVAMNIEEPGRLVDFVASSLPSLSTKDKQEILETADVQIRLDKINQHLAKELEVQQLRNKIQSEVQDRVQQTQREYYLREQLKAIQKELGEQDDSTRDADELREKVEAAGMPDDVKKEALKELGRLARMSPMAADYSVTRNYIEWLAVLPWQKSSGAGEIDIPKAKDILDEDHYDLQKVKDRILDYLSVRRLKPNMKGPILCFSGPPGVGKTSLGKSIARALGRKFVRISLGGVHDEAEIRGHRRTYIGALPGQIMQGIRRAETNDPVFMLDEIDKVGRDFRGDPSAALLEALDPEQNNSFRDNYLDVPFDLSKVLFITTANQLDPIPEPLRDRMEIIDLQGYSEEEKVHIAFRYLIPRQEEENGITKDMIEFSEEAVRRIIRHYTREAGVRNLERNIGTVCRKLARRIAEGKTEKLAVTPQTITEMLGGEKVRVDTEIAERTKRAGVVVGLAWTPAGGDILFVEATTMKGKGGFTMTGQLGDVMRESMQAALSWVKSNAGKLGIDEEFFEKHDIHIHVPAGAIPKDGPSAGVTMVTALVSLLTDKPLRPLTAMTGEITLSGNVLPIGGVKEKTLAAKRAGVKTIILPSENKMNMDEDLTPEQLQGIEVHYVKTIDEVLEIALPSNKAEEKQDARTRAEVLNEVPAV
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5559_BACAN
Sequence: MTEIVKVREQLQISLSDFQEQASLQSGQIFVVGCSTSEVLGERIGTSGTMEVAEAIFSELKQFQEQTGIELAFQCCEHLNRALVVERELAMKYQFEIVTVTPVRSAGGALATYAYHNLKDPVVIEFIKADAGMDIGDTFIGMHLKHVAVPVRTSVKEIGSAHVTMATTRGKLIGGARAVYAAKEETITCR
What are the official names of this protein?
UPF0340 protein BA_5559/GBAA_5559/BAS5166.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: VPS41_CAEBR
Sequence: MDESNDKENEFGDSFLEDSGDITRTTEDEDEAPLEPRFKYERLEGESTLPFMKTATFTSIDLHDKFIAIGTASGLIYILDHHGYGNFDSVPPLKPHRCAVSKLKFDETGSYILSCANDSKLVVSGIGNDKLCCTVNIQVMPKSICFSPDFIRQQSGHCFIMGERNLVLYEKRLFQYKASNLYSGSERDGFIHCCSWNDNLIAFTNDTGTRVYERGTEKILTSVQPTHDVDRVRSSRCPPKHMWMSENTLVIGWADTVTVLKIKGNEGMRKGEIHHIFHVSMFISGISYLPKNGSDYELFLVGLQMEGEDFDDCASVMSTMTTLTAMESSATATLKTCVIRPLGLKDYELQSEDEIVNIRLSTHTLPYMIHGLGIPYLSTYFILTTKQIIMAVPYGPEDGIKWRLQYKLYTEAFEMAKEHADMLAKTDVSPKKVGRKIIEGYLESKKARVAASWLSSICGDCKEEWEWAVDRFHDAKMSTLLGDVLPDSKPRLDPSAYEKVLLASLFNNVKLFRRLVQTWSPDLYMTSTIIDQTQWRIQQISKSEDIEDVEEVEKILMDALAHLYLYERKYESALKILMICQDFQIFNVIDKHQLFDLVKDQISDLMNINSERALRLLLDNADSVEPSFVMAKINGQPKLQLAYLTKLMSRNEGIEFADKAVQLYADHEKKKLLPFLKKNVNYNVTKARKLCSDRGFVEETIFLLAKSGNHYEAVKMMVREYKNIEKVIAYCKDQNDRDLWIHLLEVVADFPTHFSQLIIEASNCLDPILIMDKLPDDVDIPNLSEALEKLLTDFTNYVELQQCCYDSTLNDLHVLTNNLMLASDKSVSVSLMTRCSLCSQVIMNTGQDMIPRKFNDIKVFKCGHIFHLTCSASEIDRRQMIEDGICIACSDNSDHVNV
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.  Believed to act in part as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.  The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes.  Within the HOPS complex, contributes to the normal development of gut granules in the adult intestine.  May mediate the tethering of autophagosomes with lysosomes.  Has a role in the negative regulation of apoptosis.  Required for uptake of exogenous dsRNA which is used in experimental RNA silencing.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 41 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS41 family.
What are the subcellular locations of this protein?
Endosome membrane. Late endosome. Lysosome. Golgi apparatus, trans-Golgi network. Early endosome. Cytoplasmic vesicle, clathrin-coated vesicle.
Protein: GUAA_FINM2
Sequence: MKHQLVIVVDFGGQYNQLIARRVRDLNVYCEVVPYKKALDVIKEKQPIGIIFTGGPNSVYEENSPQIEKEIFELNIPILGMCYGMQLISKDFGGVVEKAKNREFGKTNAKISNQSSILKGMSDESIVWMSHTDFVSEKPEGFDIIQTTDSCPVAAIANEDKKIFAVQYHPEVNHTVEGKTLIKNFLYEICKADGDWTMENFLEEQIQKIRKTVGDKKVLLALSGGVDSSVCAALLSRAIGKNLTCVFVDHGLMRKNEGDEVEAAFKNDELNFVRVNAKDRFLNKLKGVSDPEQKRKIIGEEFIRVFEDEAKKIGSVDFLAQGTIYPDVIESGQGDASVIKSHHNVGGLPDVVDFKDLIEPLRDLFKDEVRRLGLELEMPEYLVYRQPFPGPGLGIRVMGEITEEKLEVLREADFIFRDEVAKAGIDKDINQYFAVITNNRTVGVMGDFRTYDYTLALRAVTTTDFMTADWARIPYEVLDKTSVRIINEVDHINRIVYDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ENV_HV192
Sequence: MRVEGIQRNWKQWWIWGILGFWMVMIYNVRGNLWVTVYYGVPVWKEAKTTLFCASDAKAYDAEVHNVWATHACVPTDPNPQEMVLENVTENFNMWENDMVEQMHQDIISLWDQSLKPCVKLTPLCVTLHCSNRTIDYNNRTDNMGGEIKNCSFNMTTEVRDKREKVHALFYRLDIVPLKNESSNTSGDYRLINCNTSAITQACPKVSFDPIPIHYCAPAGYAILKCNNKTFNGTGPCNNVSTIQCTHGTKPVVSTQLLLNGSLAEEEIIIRSKNLTDNVKTIIVHLNESVEINCTRPNNNTRKSIRIGPGQAFYATGEIIGDIRQAHCNISRTAWNKTLQEVGKKLAEHFPNKAIKFAKHSGGDLEITTHSFNCRGEFFYCNTSSLFNSTYTPNSTENITGTENSIITIPCRIKQIINMWQGVGRAMYAPPIEGILTCRSNITGLLLTRDGGTGMHDTEIFRPEGGDMRDNWRSELYKYKVVEIKPLGIAPTKAKRRVVEREKRAVGIGAVFLGFLGAAGSTMGAASITLTVQVRQLLSGIVQQQSNLLRAIEAQQHMLQLTVWGIKQLQTRVLAIERYLRDQQLLGIWGCSGKLICTTAVPWNSSWSNRSQEDIWNNMTWMQWDREISNYTNTIYRLLEDSQNQQEKNEQDLLALDKWQNLWTWFGITNWLWYIKIFIKIVGGLIGLRIIFAVLSIVNRVRQGYSPLSFQTLTPNPRGPDRLGGIEEEGGEQDRDRSIRLVSGFLALAWDDLRSLCLFSYHRLRDLILIAARAVELLGRSSLRGIQRGWEILKYLGGLVQYWSLELKKSAISLFDTIAIAVAEGTDRIIEVIQGIWRAICNIPRRIRQGFEAALQ
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: IF2_SYMTH
Sequence: MEPRLRVFELARELGVDSKRVLEVLQSLNVDVKNHMSTIDQKTAEKVTDAVRRTEAQEGQGAGKSAAKSAKPAAQPKPTREANPAKTSLLEDFFGSGTRPQRPLSEKRERRPLTERRPLAERRPLAERPLVDRPVTERPLAERPAAELRPGAAKAAAPARPAAEAQPVAERRAPAEAAQAAQAERRPAEKAQPAAAAKAAPPEKAGAAPVPGAVAEQKQAATPAAAEQKPAGKAEQTAGAAQAKPARAEAGTGASSRPASAAPAAQGEKRPAAAAERREEPQAEAPQTSGPSRPVPAGPGQPARPAGSGIGVPVKPAAGGKSGLGLPTRPGEKAADGARGGGSGIGLPVKPAAGQGTAARAGGLGLPQKPKAGAPRPGGGLGAPQRPGRRGAPLAIPKLDPKVAEQAKAGEGKPRYGQSGDKRRADLYDRREHPSSQPSEEKLFGQRPKRKASAQERRVLKPITVTGPMSVKDLAHEMGVTAAEVIKTLLTGFGIMATINQELDVDTCVLVASEFGVEATVEQKEDIIEVYDRVEDPDEPAELKKPRHPVVTIMGHVDHGKTSLLDAIRQAKVAAGEAGGITQHIGAYEVELNGRKITFLDTPGHEAFTAMRARGANVTDIAVLVVAADDSVMPQTVESINHAKAANVPILVAINKIDKPEANPQRVMQDLTQYGLVPEEWGGDTIMVPVSAKQKTNLDLLLENILVLAEVSDLKANPDKPAAGTILEAALDKARGPVATVLVQAGTLNTGDVFVAGTSWGRVRAMFDHRGRKLKSAGPSTPVRVLGFDSVPQAGDVFRVTPDEKTARAIAEKRIAKAQAERLAQKAISLDDFMNQVAQGEIKDLNVIVKADVQGSVEAIRGQLEKLRNEEVKVKVIHAGVGAISESDVMLAVASKAIIIGFNVRPDDRASRAADEHGIDVRTYSVIYDIVDDIEAAMKGMLKPKIEEVILGKAEVRETFKVPKVGMAAGCMVIQGKVTRNARYRLIRDGVVVWDGEINALRRFKDEVREVSEGYECGITLQNFHDFKRGDILEAYELQEIKAG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_RICCN
Sequence: MTKIVRSKYKASRRLGVSLWGDSKDAFNTRNYRPGQHGQNTMIKTSDYGLHLKAKQRLKCHYGRVTEKQFRNIFALAQKMKGNTGENFIGLLESRLDTVVYRMNIAPTIFAARQLVSHGHIKLNGKKADIASIRLKAGDVIEVKESVKQIPLIQESVSKQGQTTPGYLSFDVPSLTGKYLRVPALSDVPYPFEAEVHLVIELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CARB_LACLA
Sequence: MPKRNDIKKIMIIGSGPIIIGQAAEFDYAGTQACLALKEEGYEVVLVNSNPATIMTDREIADTVYIEPITLEFVSKILRKERPDALLPTLGGQTGLNMAMELSKIGILEELNVELLGTKLSAIDQAEDRELFKELCERIGEPLCASDIATTVDEAVEIADKIGYPIIVRPAFTMGGTGGGICDTEEELREIVANGLKLSPVTQCLIEESIAGYKEIEYEVMRDSADNAIVVCNMENFDPVGVHTGDSIVFAPSQTLSDNEYQMLRDASLNIIRALKIEGGCNVQLALDPHSYEYRVIEVNPRVSRSSALASKATGYPIAKMSAKIAIGMTLDEIINPVTNKTYAMFEPALDYVVAKIARFPFDKFENGDRHLGTQMKATGEVMAIGRNIEESLLKAVRSLEIGVFHNDLQEAQDADDEILYEKMVKTQDDRLFYVSEAIRRGIPIEEIADLTKIDIFFLDKLLHIVEIEDQLKVNIFEPELLKTAKKNGFSDRQIAKLWNVSPEEVRRRRQENRTIPVYKMVDTCAAEFESSTPYFYSTYEWENESKRSSKEKIIVLGSGPIRIGQGVEFDYATVHCVKALQALGKEAIVINSNPETVSTDFSISDKLYFEPLTFEDVMNIIDLEQPEGVIVQFGGQTAINLAEPLSKAGVKILGTQVEDLDRAEDRDLFEKALQDLEIPQPPGATATNEEEAVANANKIGYPVLIRPSFVLGGRAMEIINNEKDLRDYMNRAVKASPEHPVLVDSYLQGRECEVDAICDGTEVLLPGIMEHIERAGVHSGDSMAVYPPQTFSQEIIDTIVDYTKRLAIGLNCIGMMNIQFVIFEEQVYVIEVNPRASRTVPFLSKVTNIPMAQLATQMILGKNLKDLGYTEGLAETPDMVHVKAPVFSFTKLAKVDSLLGPEMKSTGEAMGSDVTLEKALYKSFEAAKLHMADYGSVLFTVADEDKEETLALAKDFAEIGYSLVATQGTAAFFKENGLYVREVEKLAGGEDEEGTLVEDIRHGRVQAVVNTMGNTRASLTTATDGFRIRQEAISRGIPLFTSLDTVAAILKVMQSRSFTTKNI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: VP7_ROTHT
Sequence: MYGIEYTTVLFYLISFVLVSYILKTIIKIMDYIIYRITFVIVVLSVLSNAQNYGINLPITGSMDTAYANSTQDNNFLFSTLCLYYPSEAPTQISDTEWKDTLSQLFLTKGWPTGSVYFNEYSNVLEFSIDPKLYCDYNVVLIRFVSGEELDISELADLILNEWLCNPMDITLYYYQQTGEANKWISMGSSCTVKVCPLNTQTLGIGCQTTNTATFETVADSEKLAIIDVVDSVNHKLNITSTTCTIRNCNKLGPRENVAIIQVGGSNILDITADPTTSPQTERMMRVNWKKWWQVFYTVVDYINQIVQVMSKRSRSLDSSSFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: RL13_BURTA
Sequence: MKTFSAKAHEVTREWYVIDATDKVLGRVASEVARRLRGKHKPEFTPHVDTGDFIIVINASKLKVTGNKTLDKKYYRHSGYPGGIYETTFGKMQERFPGRALEKAVKGMLPKGPLGYAMIKKLKVYAEATHPHSAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL19_CAMC5
Sequence: MRNKYIQAFEDAQIASKSVPDFRAGDTLRVAIRIHEGDKTRVQNFEGICIARRGSGVGETFIIRKIGANSVGVERIFPIYSDSIEEIVVLRKGRVRRAKLFYLRDLRGKAAKIRELRK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PRR32_HUMAN
Sequence: MACIENVLGGHAPSPLVVSVDKNGNQELHHDMPLQCLSSKPEDDAEPWGQPQVPLRPSVNVLTDLDSKQLEWPSERTGSCIPLHSLRAHRHPYGPPPAVAEESLATAEVNSSDALAGWRQEGQDAINVSWEVSGGPPALIVGGTKVNNGGTERGSNNARLHVALPQGKGFFPPRGPQVRGPSHIPTLRSGIVMEVPPGNTRIACRGKLAHVSFPLRGPCHPMHNWPRPIPLSSSTPGLPSCSTVHCFIPPRPPIFNPFLTMPLPFAPPPIFGPPLPSYFAHFHSGGMPAPASPNREHS
What are the official names of this protein?
Proline-rich protein 32.
Protein: RGL2_MOUSE
Sequence: MLPRPLRLLLDTTPPGGVVLSSFRSRDPEEGGDPGGRAVGGGQEEEDEEEEEASVSVWDEEEDGATFTVTSRQYRPLDPLAPLPPPRSSRRLRAGTLEALVRHLLDARTAGADMMFTPALLATHRAFTSTPALFGLVADRLEALESHPPGELERTTGVAISVLSTWLASHPEDFGSEVKGQLDRLESFLLRTGYAAREGVVGGSADLIRNLRARVDPRAPDLPKPLALPGDSPADPTDVLVFLADHLAEQLTLLDAELFLNLIPSQCLGGLWGHRDRPGHSHLCPSVRATVTQFNKVAGAVVSSVLGATSIGEGPREVTVRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGETTRDSLRVFSSLCQIFSEEDNYSQSRELLMQEVKPQPPVEPHSKKAPRSGFRGGGVVPYLGTFLKDLVMLDAASKDELENGYINFDKRRKEFAILSELLRLQKECRGYDLRPNSDIQQWLQGLQPLTEAQSHRVSCEVEPPGTSDSPAARTPRPTLVITQWTEVLGSVGGPTPLVSWDRPSVGGDEVPGTPAPLLTRLAQHMKWPSVSSLDSALESSPSLHSPADPGHLSPPASSPRPSRGHRRSASCGSPLSGNTGEGTSRSAGCGGGVSGPGSSDCRIIRVQMELGEDGSVYKSILVTSQDKAPSVISRVLKKNNRDSAVASEFELVQLLPGDRELTIPHSANVFYAMDGASHDFLLRQRRRPSAATPGSHSGPSASGTPPSEGGGGSFPRIKATGRKIARALF
What is the function of this protein?
Probable guanine nucleotide exchange factor.  Putative effector of Ras and/or Rap.  Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
What are the official names of this protein?
Ral guanine nucleotide dissociation stimulator-like 2, RalGDS-like 2, RalGDS-like factor, Ras-associated protein RAB2L.
Protein: CXA1_ERIEU
Sequence: MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGANVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGIKDRVKGKSDLYHATTGPLSPSKDRGSPTYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDAQNSKKLAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
What is the function of this protein?
Gap junction protein that acts as a regulator of bladder capacity.  A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.  May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.  Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract.  May play a role in cell growth inhibition through the regulation of NOV expression and localization.  Plays an essential role in gap junction communication in the ventricles (By similarity).
What are the official names of this protein?
Gap junction alpha-1 protein, Connexin-43, Cx43.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65.
Protein: HOG1_TRIHA
Sequence: MAEFVRAQIFGTTFEITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENVISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVKSLPKRERQPLRNKFKNADDSAIDLLERMLVFDPKKRVTATQALAHEYLQPYHDPTDEPVADEKFDWSFNDADLPVDTWKIMMYSEILDYHNVEGAPNMEEQFPPQ
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes.
What are the official names of this protein?
Mitogen-activated protein kinase hog1, MAP kinase hog1, Osmotic stress MAP kinase, ThHog1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Concentrates within the nucleus in response to hyperosmotic conditions and phosphorylation.
Protein: METI_HAEIN
Sequence: MWGVVATATYETVYISFASTLLAVLVGVPVGIWTFLTGKNEILQNNRTHFVLNTIINIGRSIPFIILLLILLPVTRFIVGTVLGTTAAIIPLSICAMPFVARLTANALMEIPNGLTEAAQAMGATKWQIVRKFYLSEALPTLINGVTLTLVTLVGYSAMAGTQGGGGLGSLAINYGRIRNMPYVTWVATIIIVLFVMISQKLGDTLAKKVDHR
What is the function of this protein?
Part of the binding-protein-dependent transport system for D-methionine.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable D-methionine transport system permease protein MetI.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.