PharMolix/UniProtQA huggingface dataset:
Protein: ATPE_CITK8
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQFGHEEFIYLSGGILEVQPGSVTVLADTAIRGQDLDEARALEAKRKAEERIKSSHGDVDYAQASAELAKAIAKLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSBH_PROM4
Sequence: MGQKTALGSLLKSIGNSGQGKVVAGWGAVPVMAFIGVLLLVFLVILLQIYNQSLLLQGFSVDWNGVK
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HFQ_RHILW
Sequence: MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPMQMFESEEAAS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: ILEC1_XERSP
Sequence: CSKGGVGRGYGIG
What is the function of this protein?
Inulin-specific lectin.  Has hemagglutinating activity towards rabbit erythrocytes.  Has mitogenic activity towards murine splenocytes.
What are the official names of this protein?
Inulin-specific lectin.
Protein: PDE6D_DROSI
Sequence: MGSDDQSAGDRIQKGFQINYMILRDADSGKIIWQENKDFSAPDQEHEARVPVKILDMRAVSREINFSTIESMENFRLDQKVLFKGRIMEEWFFEMGFVGANTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNETLITKSVVRLYYI
What are the official names of this protein?
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CLPX_GEOTN
Sequence: MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGNEEEFEFKDVPKPVEIREILDEYVIGQDEAKKSLAVAVYNHYKRINSGSKIDDVELSKSNILMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGKKVIGFGAEMNQADVDEKNLLSKVLPEDLLKFGLIPEFIGRLPVITTLEPLDEQALIDILTKPKNAIVKQYKKMLELDGVELEFEEAALREIAKKAIERKTGARGLRSIIEGIMLDVMFELPSREDVQKCIITVDTVCGKKPPKLIRHDGTVVEHERKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ARGC_DEHMB
Sequence: MKKYKAGIINVTGYAGLELARILESHPSVELCSVTGRSLAGKKLSDVFPYLHRLDLPITENLEGQVDVAFLALPHKEGAALVPALLEKGMRVIDISADFRLKDPALYQAWYGFEHPCPGLLEEAVYGLPELKRKDIAGARLVANPGCYPTSAILGLVPAFKSDLIEPSAIIDAKSGLSGSGRTPTVKTIFCEADEDVCAYSIGTHRHQPEIAQELCRASGGVIPRVTFCPHLVPMSRGILSTAYARLKQPVTDEEVKEIYRQFYKDEPFVKVTAEPPHTRYTRGTNMCFIYPVVDALNEQLIVISCIDNLVKGAAGQAVQNMNIMLGLAETEGLEAMATLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT10_EPTST
Sequence: SGSCQLKTCWQVSPDFRSVGDTLREKFQSALFLPLHNGHGGIGGLLVPRDTQLVYFERSPTFCEQEDDIGSPGTRGRLCERTEQGFSGCSSMCCGRGHNVVRETRVERCNCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-10.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: AC4CH_SERP5
Sequence: MSREITFFSRFEQDILAGRKTITIRDASESHFQPGEVLRVSRNEDNVFFCQIEVLSVTPVRLDGLTEQHARQENMSLGELKQVIKEIYPGLDELFVITFAKR
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: KYNB_CUPNH
Sequence: MTAPNQDPRRLWDISPPLSPATPVWPGDTPFQQQPAWQMDEHCPVNVGRITLSPHTGAHADAPLHYAADGAPIGAVPLTPYLGTCRVIHCIGASPVVEPRHIEHALAGLPPRVLLRTYRQAPLAQWDPHFCAVAAETIALLAAHGVQLVGIDTPSLDPQESKTMDAHNAVRRHGLAILEGIVLDEVDAGDYELIALPLRFAGLDASPVRAVLRSLD
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: KWL1_MAIZE
Sequence: MATVGGNRALYAVVALPLLATLLHGPMRLSHAFPYRSLLQTCQPSGSIQGRSGNCNTENGSECCKNGRRYTTYGCSPPVTGSTRAVLTLNSFAEGGDGGGAAACTGKFYDDSKKVVALSTGWYNGGSRCRKHIMIHAGNGNSVSALVVDECDSTVGCDKDHNFEPPCRNNIVDGSPAVWDALGLNKDDGQAQITWSDE
What is the function of this protein?
Specifically blocks the catalytic activity of the chorismate mutase Cmu1 from the fungal pathogen Ustilago maydis.  Hinders substrate access to the active site of Cmu1 through intimate interactions (PubMed:30651637).  A structural feature specific to the fungal secreted Cmu1 called extensive loop region (ELR) is required for the intimate interaction (PubMed:30651637).  Does not interact with its own chorismate mutases (PubMed:30651637).  The secreted fungal Cmu1 presumably affects biosynthesis of the plant immune signal salicylic acid by channelling chorismate into the phenylpropanoid pathway (PubMed:30651637).
What are the official names of this protein?
Kiwellin-1, ZmKWL1.
What is the protein family that this protein belongs to?
Belongs to the kiwellin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: YIDC_NITOC
Sequence: MENYRLILFSALVLVLFLMWDAWQTDYGPIPLLPPPPQPTASSGESSPVLPEAVPDAPPPEMADMDTAPILTGQKTIEVKTDLLAIKIGMASGDLYEVQLLNYPVSLKKPNEPVTLLHKRDPDLFVTQSGLRAASGPSITHETVQFSAPKTYYELIEDESSLKVPLTWEDENGIKVTKTYIFQRDSYQIDLNIKIENGTDQAWMGRAYAQFSRTPPESGGMFARSYVGAVFSTQEQEYQKVDFGDLASQSFDRRSSGGWVAMIQHYFVAAWVPREQGTNYYYGKHVQNSRYIAGVMPPQQTIAPGESGQFNLALFTGPKIQDQLAAVAPKLNLTVDYGKLTILAEPLFWLMSWFHNLVGNWGWAIVLLTFVVKLVFFKLSQTSYRSMARMRKLQPRLLALKERYGDDRQKVGQAMMELYRKEKVNPMGGCLPIVVQIPVFIALYWMLLESVELRQAPFIFWIQDLTSKDPYYILPLLMGVSMFVQQKLSPAPTDPIQAKVMALMPVMFTVFFVMFPAGLVLYWVVNNILSIAQQWYITRQIEQEG
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMJ_FRATT
Sequence: MQINISNLDVKNHLDKFIEDRLEYEFCKQDKYLYLENDNLKLHYNNKELFIDFNDSEILNRINPKTKKCSVVQAIEGRSKAKLTILDTTAGLGRDTFTLAARGHTLLTLEKDSYLYLLLKDALQRAQQINYLKEIANRITLINIDSNEYILTTDKSFDCVYVDPMFPPRKKSAKVKQGMQILHQVGFNDEVSNSNLLDNIIQTQISPKAVVKRPINAEFLSNKKPSSQLKGKTNRFDIYSL
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_TRIV2
Sequence: MAEFEKSISFDGRDIRLKVGLLAPQAGGSVLIESGDTAVLVTATRSAGREGIDFLPLTVDYEERLYAAGRIPGGIMRREGRPPEKTILTSRLIDRPLRPLFPSWLRDDLQIVALTMSMDEQVPPDVLAVTGASIATLIAKIPFNGPMAAVRVGLVGDDFIINPTYAEIEAGDLDLVVAGSPHGVIMVEAGANQLPERDIIEAIDFGYEAVRDLIKAQLDLVAELGLEIVQEAPPEVDQTLENYIRDRASDEIKKILAQFELTKPERDAALDVVKDNIATAIAELPEEDPIRLAATANSKALGNTFKDITKYFMRRQIVEDNVRVDGRKLDQVRPVSSQVGVLPKRVHGSGLFNRGLTQVLSACTLGTPGDAQNLNDDLQTDQSKRYLHHYNFPPFSVGETKPLRAPGRREIGHGALAERAILPVLPPKEQFPYVIRVVSEVLSSNGSTSMGSVCGSTLALMDAGVPILKPVSGAAMGLIKEGDEVRVLTDIQGIEDFLGDMDFKVAGTDAGITALQMDMKISGLSLEVIAQAIHQAKDARLHILDKMLQTIDTPRTETSPYAPRLLTIKIDPDMIGLVIGPGGKTIKGITEETGAKIDIEDDGTVTISAVDENKAKRARNIVQGMTRKLNEGDVYAGRVTRIIPIGAFVEFLPGKEGMIHISQLADYRVGKVEDEVAVGDEVIVKVREIDNKGRINLTRLGIHPDQAAAAREAAAVNR
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCN11_ORYSJ
Sequence: MMPVRTYHHHHHHNNSNNHRLRRIIPRVLLAVFAIYAVSFAAYLLRHQSPHPHPHPAADPERDAVDAAGGGGGGGAVDRVRVEAPSSQKPWPRLPSFLPWTSASVRPPPKHSCEGYFGNGFSRLVDVLPARGGGGGGWFRCHHSETLRSSICEGGRVRLDPGLIAMSRGGEPLDQVMGRAEEEELPKYEPGALQVEAAAKRTGPLVEAGFLDAYVPTGGIGMHTMRSLLDSGRVVPPGELHCSQWVEEPTLLVTRFEYANLFHTITDWYSAYVSSRVTDLPNRPNVVFVDGHCKAQLEQTWEALFSNVTYVKNFSGPVCFRHAILSPLGYETALFKGLSESFSCEGASAESLREKPDHQKTARLSEFGEMILASFDLLRDDILSSKTSNGLNVLFVRREDYLAHPRHSGKVESRLSNEKEVYDAIEGWAKGQKCKINVINGLFAHMNMKEQLRAIQEASVVIGAHGAGLTHLVSATPDTKVLEIISSMYRRPHFALISHWKSLEYHAINLPGSYARVTDVINELSNILKGFGC
What is the function of this protein?
Glycosyltransferase involved in the xylosylation of N-glycans (PubMed:26025522).  Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans (PubMed:26025522).  Beta-1,2-linked xylose residues on N-glycans are critical for seed germination and plant development and growth under conditions of abiotic stress (PubMed:26025522).
What are the official names of this protein?
Beta-1,2-xylosyltransferase RCN11, OsXylT, Protein REDUCED CULM NUMBER 11.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 61 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: JUN_HUMAN
Sequence: MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
What is the function of this protein?
Transcription factor that recognizes and binds to the AP-1 consensus motif 5'-TGA[GC]TCA-3' (PubMed:10995748, PubMed:22083952).  Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to the AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing its transcriptional activity (By similarity).  Together with FOSB, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway (PubMed:12618758).  Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (PubMed:17210646).  Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306).  Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
What are the official names of this protein?
Transcription factor Jun, Activator protein 1, AP1, Proto-oncogene c-Jun, Transcription factor AP-1 subunit Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Jun subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_RUMCH
Sequence: MPTFNQLVRKGRKVIEKKSNSPALQKGFNSKKKKPTDVNSPQKRGVCTVVKTSTPKKPNSALRKVARVRLTNGIEVSAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGTLDTAGVAKRMQARSKYGAKRPKAGAASK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MACD1_HUMAN
Sequence: MSLQSRLSGRLAQLRAAGQLLVPPRPRPGHLAGATRTRSSTCGPPAFLGVFGRRARTSAGVGAWGAAAVGRTAGVRTWAPLAMAAKVDLSTSTDWKEAKSFLKGLSDKQREEHYFCKDFVRLKKIPTWKEMAKGVAVKVEEPRYKKDKQLNEKISLLRSDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQSCKTGKAKITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPCEAAAEIVLATLREWLEQHKDKVDRLIICVFLEKDEDIYRSRLPHYFPVA
What is the function of this protein?
Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety (PubMed:23474714, PubMed:23474712).  Inactive towards proteins bearing poly-ADP-ribose (PubMed:23474714, PubMed:23474712).  Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins (PubMed:21257746).  Plays a role in estrogen signaling (PubMed:17893710, PubMed:17914104, PubMed:19403568).  Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen (PubMed:19022849).  May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation (PubMed:17893710, PubMed:17914104).  Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction (PubMed:17914104).  Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells (PubMed:17893710).  Enhances ESR1-mediated transcription activity (PubMed:17914104).
What are the official names of this protein?
ADP-ribose glycohydrolase MACROD1, MACRO domain-containing protein 1, O-acetyl-ADP-ribose deacetylase MACROD1, Protein LRP16, [Protein ADP-ribosylaspartate] hydrolase MACROD1, [Protein ADP-ribosylglutamate] hydrolase MACROD1.
What are the subcellular locations of this protein?
Nucleus. Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins.
Protein: S36A3_HUMAN
Sequence: MSLLGRDYNSELNSLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSMANSTGVHA
What are the official names of this protein?
Proton-coupled amino acid transporter 3, Proton/amino acid transporter 3, Solute carrier family 36 member 3, Tramdorin-2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PHF13_MOUSE
Sequence: MDSDSCAAAFHPEEYSPTCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDTGFSDITPSVPDRCFSHLQPSLLQRAKPSNYLLDRKTTDKLKKKKRRKRRDSDIPVKEGFRESLLKLEAADPYVETPSSPTMQDIPQASADPCSGWDSDTPSSGSCATVSPDQVTEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRMGSRKLFLD
What is the function of this protein?
Modulates chromatin structure.  Required for normal chromosome condensation during the early stages of mitosis.  Required for normal chromosome separation during mitosis (By similarity).
What are the official names of this protein?
PHD finger protein 13.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Note=Predominantly bound to chromatin, but a minor proportion is also detected in the nucleoplasm.
Protein: YBHG_SALSV
Sequence: MKKPVVIGLAIAAIVAVIAGGTWWYQSRQDDGLTLYGNVDIRTVNISFRVGGRLASLNVDEGDAIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVRQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLSQYRTGNREQDIAQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRAVEPGSMLNAGSTVLTLSLTRPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYHGKIGFVSPTAEFTPKTVETPDLRTDLVYRLRIIVTDADDALRQGMPVTVKFNDEARHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: COX6A_ONCMY
Sequence: MASPASMAARRVLSAASHAGHEGGSARTWKILSFVLALPGVAVCIANAYMKMQQHSHEPPEFVAYSHLRIRTKKWPWGDGNHSLFHNPHENALPEGYEGPRH
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6A, mitochondrial, Cytochrome c oxidase polypeptide VIa.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RNB_ECOSM
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETAYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4M_PARTE
Sequence: MFAVYLVFSFKKPEASKADLDFFMLTFKYILKGSFFLMLVLALFCALFTFDLMFSAKNLLYPNEYIWDSGDFFFYKNGALKFSLNLYGLILVFLCLLTGFVAISTVDNLYSEDKLKFYLIFFQFFLAVLGFIKCSDLIAFFFFYEVLMLGSVLVVFFGSYSKKSIHAVIYFVAWTQLGSLFVLLACLYIYSLTNSTNFFVIKTFVFSKTQAMTIYSLLFVGFGIKFPIWPLHYWLTKTHVEASTGFSIYLSGFLVKTALFGFYRLTNLIQVELDTTFFLAVLVAGVIDSSLNMWSQTDLKKLVAYCTIQEMNLIAIFFLKGDSSLIAYGFLFTIMHALMSTLMFFLVECIYSRYKSRSTLVVNGVFFSFNNLALAIIFMVLFFSGILGTLKFVCEFFVFNLTLHVSWPIGVIFVVVVSAIGLIGFSKNWFNAIFCAPSKDVGPDALDLSKKELYIIFLCFAGLIFLTFLPFLMI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: NLPD_YEREN
Sequence: DIAGSRGQPIFATANGRVVYAGNALGGYGNLIIIKHNDDYLSAYVHNDTMLVREQEEVKAGQKIATMGSTGTSSVRLHFEIRYKGKSVNPLRYLPQR
What are the official names of this protein?
Lipoprotein NlpD.
What is the protein family that this protein belongs to?
Belongs to the E.coli NlpD/Haemophilus LppB family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: GP30_BPSP1
Sequence: MSRIGQVCEAFRENHWEPATIISENGSLSVTVRYEDGETEELISNLVRNSELGHPEVKKEETTQQPEKGEGMAEPKIEGTCLDHFRWYNTITEKRPDNSKLFPVVSALMAVQYDKEGTYGSSWVGKGEHRGIMPNIDRKYDRLDTMTANEIEGKAKTLAQLESSFDSMNSNEKEALHESKIDAVADLANYCLLYMTFIKDNFPKMYNAWFEKNVPQYLRDKFPRL
What is the function of this protein?
Essential for DNA synthesis.
What are the official names of this protein?
Gene 30 protein, GP30.
Protein: HIS3_NOCSJ
Sequence: MTTLDPAIAGRLKRNPDGLVPAVVQQHDTGEVLMLGWMDDEALARTLTTGRATYWSRSRQEYWLKGETSGHVQWVKEVRLDCDGDTILVKVDQVGAACHTGDRTCFDADLLSGADRPGPDARG
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHBQ_ECOHS
Sequence: MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAELLSSLQTPEIKSD
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.