PharMolix/UniProtQA huggingface dataset:
Protein: RPP30_HUMAN
Sequence: MAVFADLDLRAGSDLKALRGLVETAAHLGYSVVAINHIVDFKEKKQEIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVSDPSHCNVLRATSSRARLYDVVAVFPKTEKLFHIACTHLDVDLVCITVTEKLPFYFKRPPINVAIDRGLAFELVYSPAIKDSTMRRYTISSALNLMQICKGKNVIISSAAERPLEIRGPYDVANLGLLFGLSESDAKAAVSTNCRAALLHGETRKTAFGIISTVKKPRPSEGDEDCLPASKKAKCEG
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9037013, PubMed:9630247, PubMed:30454648).  Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
What are the official names of this protein?
Ribonuclease P protein subunit p30, RNaseP protein p30, RNase P subunit 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TOLB_VIBC3
Sequence: MFKRLVFVLMLIGTGFSNIANAALELVITDGIDSARPIAIVPFKWEGATKLPEDVSAVIASDLQRSGKFSPVPTSKMPQTPYSEEQVNFGKWTSMGVDSLLTGTITQNAEGSYVISYQLVDIVRGQLTQGQSKALSQDGQLVLSKDHVLFNKVATVPASRMREYAHRIADLVYEELTGERGAFLTRIAYVVVNDKDPYPYQLRIADYDGYNERLVLRSKQPLMSPAWSPDGQTLAYVSFQNGQAEIYMMNIYSGKREKLTSFPRHNGAPRFSPDGKTLALVLSKTGNLQVYTMDLATRRLTEVTSGRSNNTEPFWHPDGKSLIFTSDRGGKPQIYQVNLSGGETKRLTWQGSQNLGGQITPDGKFLVMVNRSDSGFNLAKQDLETGAMQILTKTLLDESPSIAPNGGMVIYSSIYNKANVLSMVSIDGRFKARLPATNGRVRAPAWSPFL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GATA_CORDI
Sequence: MNKYLVPDSGLTSLSAAELAEKIHSREVTSREVTQAHLDRINDVDGTLHAFLHVGVEEALAAADAVDESLDKGEAPASALAGVPLALKDVFVTTDAPTTCASKMLEGYVAPYDATVTKKIREAGIPILGKTNMDEFAMGSSTENSAYGPTLNPWDIERTPGGSGGGTSAALASGEAPLGIGTDTGGSIRQPAALTNTVGVKPTYGTVSRYGLVACASSLDQGGPTARTVLDTALLHEVIAGHDKYDATSVNRAVAPVVAAAREGARGDLKGTKIGVVKQFDREGYQPGVLEQFHKSVEQLTAQGAEIVEVDCPHFDDALAAYYLILPCEVSSNLARFDGMRYGLREGDDGTHSAEEVMSLSRAAGFGPEVKRRIILGTYALSVGYYDAYYLQAQRVRTLIAQDFAVAYDKCDVLVSPTTPTTAFKLGEKVSDPLAMYNFDLCTLPLNLAGLCGMSLPSGLAPDSQLPTGLQIMAPAFQDDRLYKVGAAFEVGQK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: DNAT_SALCH
Sequence: MSSRILTSDVIGIDVLLHDHHAVLAKSTGGAVAVFANNAPAFYAVTPARMAELLALEEKLSRPGSDVALDAQFYEEPEAAPVAIPCGKFAMYPAWQPDADFQRQAALWGVALREPVTAEELAAFIAYWQAEGKVFHHIQWQQKLARSVQISRSSNGGMPQRDINSVSEPDNHIPPGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: HUTGL_PSEA7
Sequence: MHPAPDMSLWQGRIDSQEGAGALRWHQWIRPYHESAGAASVLLGFASDEGVRRNQGRQGARQGPPALRRALANLAWHGEQALYDAGDIEAAEDLEGAQERYARRVAELLGRGHQVVGLGGGHEIAYASFSGLAHHLGRDGGTPRIGILNFDAHFDLRHAEQASSGTPFRQIAEHCEASGWPFAYCCLGVSRLSNTAALFDQAQRLGVRYLLDRQVQPWNLERSEAFLDSFLQSIEHLYLTVCLDVLPAAQAPGVSAPSAHGVEMSLVEHLVRRAKASGKLRLADIAELNPQFDNDQRTARIAARLVDALVN
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: HEM1_SULIY
Sequence: MTSNEELLQNYCSILFTYKTIGISNLHLYYFRETEIKSLRQLINAEFAILQTCNRVEIYLYSNTNTISEINKMIQYLNNVHNEPIGNQARVICGKDSIKHLFLVASGADSLSIGEYEILSQIRSTIDMFKKLGFSGKYLQILFERAIKVGRKVREETSISKGKVGIYSLAIDEAKRQFNNFYDRKIVIVGAGEMGQKIANMLYNEGVKNVTIMNRTVEKAKQLALKFGYNYEKLDLDKLGSFDIAFISISHENLRLENKWNTLIVDITVPPLFTGNNVITLEELEKISKLNFKAREEELVKINKLVEDGIDELIYDYKKEIYSEFMSKIMKRVETIRENEIVRAYKELEKLGINNQQVKEILDLMTRSIIKKSFQPLFDNVRSLVFDGENSINYINFLIDIFKDGNIPIFETKKIKKKQISKRSSS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RTPA_BACSU
Sequence: MVIATDDLEVACPKCERAGEIEGTPCPACSGKGVILTAQGYTLLDFIQKHLNK
What is the function of this protein?
By forming a complex with tryptophan-activated TRAP, and masking its RNA binding site, it inhibits TRAP's RNA binding ability, thereby abolishing TRAP regulation of gene expression, leading to antitermination and increased trp operon expression.  AT acts by competing with messenger RNA for the RNA binding domain of TRAP.
What are the official names of this protein?
Tryptophan RNA-binding attenuator protein inhibitory protein, Anti-TRAP protein, AT.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_PASMU
Sequence: MARTVFCEYLKQESEGLDFQLYPGELGKRIFDSISKQAWREWMKKQTMLVNEKKLNMMNADHRQLLEQEMVNFLFEGKDVHIEGYVPPTE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: COBQ_GLOVI
Sequence: MAALMVVGTSSHAGKSLLVTALGRLFHRRGVKVAPFKGQNMALNAYVTAEGHEIGHAQAVQAWACGLEPSVAMNPILLKPQGNMTSQVILKGKPAGVCGAVDYYRDYFEPGWQAVVEALAELQSQYELVICEGAGSPAEVNLRHRDLTNMRVALHLGAPTLLVTDIDRGGALAHVVGTLQVLPPEERALIKGIVINKFRGSLALLQPGLDWLAQYTGVPVVGVLPWLEMALPEEDSMGLFDRRGARKQAQLEIVVIRLPRIANFTDFDALEAEPSVRVRYVSPDGYLGHPDAIILPGSKATIPDLLALEASGMAAQIRAYGGVILGICGGLQILGSTIDDPEGFEGHPGRHPGLGLIEATTVFEPLKITRQVQVESRLPAGEPVVGYEIHQGQTTFAPTLEALFAEPHLGVVSSNRRVWGTYLHGLLDNHAWRRHWLNALRERRGLPQLPVQSGHYREQREEMFERLADAWEPHLPIDGFAQLAGFASQV
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: OCCR_RHIRD
Sequence: MNLRQVEAFRAVMLTGQMTAAAELMLVTQPAISRLIKDFEQATKLQLFERRGNHIIPTQEAKTLWKEVDRAFVGLNHIGNLAADIGRQAAGTLRIAAMPALANGLLPRFLAQFIRDRPNLQVSLMGLPSSMVMEAVASGRADIGYADGPQERQGFLIETRSLPAVVAVPMGHRLAGLDRVTPQDLAGERIIKQETGTLFAMRVEVAIGGIQRRPSIEVSLSHTALSLVREGAGIAIIDPAAAIEFTDRIVLRPFSIFIDAGFLEVRSAIGAPSTIVDRFTTEFWRFHDDLMKQNGLME
What is the function of this protein?
Positive regulatory protein for the occ operon involved in octopine catabolism and uptake.  Also acts as a negative regulator of its expression.
What are the official names of this protein?
Octopine catabolism/uptake operon regulatory protein OccR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: EF2_THESM
Sequence: MGKREEMIKEIKELMLQPERIRNMGIAAHIDHGKTTLSDNLLAGAGMISEELAGKQLVLDFDEQEQARGITINAANVSMIHEYGDQKYLVNLIDTPGHVDFGGDVTRAMRAIDGAIIVVDAVEGVMPQTETVLRQALREYVKPVLFINKVDRLIKELKLNPQQMQERFVRVITDVNRLIRKYAPAEFKNKWLVNVNDGSVAFGSAYYNWALSVPYMKKTGVSFKDIIDLTNAGDLKTLRKKAPLHVVVLDMVVRHLPNPVEAQKYRIPHLWRGEIESEIGQSMASCNPKGKMVMVVTKIIIDKHAGEVATGRVWSGTVKTGQEVHIITAKRKARIQQVGIYMGPERINMEAVPAGNIVAVTGLRDAMAGETVAEEPIEPFEALHYTSEPVVTVAIEAKNVKDLPRLIEALRQLAKEDPTLHVKIDEETGQHLLSGMGELHLEVKLVHLKEQWGVDVDVSEPIVVYRESITKQSPIVEGKSPNKHNRFYIVVEPMPDEIYQAIREGEIPEGRPKDTKVVAKKLAELGMDYEIARGIVDIYNGNMFLDNTKGLQYLNEVMDLLVDGFHQAMDEGPLAREPVMKVIVRLVDAKIHEDNVHRGPAQIYPAIRTAIHCAMMKSNPVLYEPYQKVVINVPYEYMGSVSREMNQRRGQLIDMRQEGEVMIIISEAPVAEMFGFAGAIRGATSGRALWSTEHAGFKRVPTELAINIIRQIRQRKGLNPNPPTEKDICPQQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHAA_MYCBT
Sequence: MTAFGVEPYGQPKYLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSGPDRYSYGEQRDFLFALWDALDLGDHVVLVLHDWGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRSPQGEPMALEHNIFVERVLPGAILRQLSDEEMNHYRRPFVNGGEDRRPTLSWPRNLPIDGEPAEVVALVNEYRSWLEETDMPKLFINAEPGAIITGRIRDYVRSWPNQTEITVPGVHFVQEDSPEEIGAAIAQFVRQLRSAAGV
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: RUVC_HAEIG
Sequence: MSIILGIDPGSRVTGYGVIRQTGRHLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFQPDMFAIEQVFMAKNADSALKLGQARGTAIVAAVNHDLPVFEYAARLVKQTVVGIGSADKVQVQEMVTRILKLSDKPQADAADALAIAITHAHSIQHSLHIANSVKMTETQEKMTALLKTRYSRGRFRLKI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: FTSB_HAEIE
Sequence: MRLLILILLSVLVLFQHDFWFGSNGFLDYRQNAEKIKENQAENEKLSQRNQRINAEIQGLTKGFEAIEERARMQHGLVKENEVFYHIVKESK
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: HYPA_PECAS
Sequence: MHELTLCQRAIEIIEQQAQQHGAKKVTAVWLEIGAFSCVETSSLDFCFGMVCRRTLAEGCQLHLHQQEAECWCYDCQQSVTLLTIQVRRCPQCQGDNLRIVADDGIQLKRMEIEQEI
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: RS12_XYLFA
Sequence: MATINQLVRKPRQASTYKSASPALDKCPQRRGVCTRVYTSTPKKPNSALRKVAKVRLTNQEEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDAAGVAKRRQGRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: COX19_KLULA
Sequence: MSANPGNSLKALSPTPPERGSFPLDHDGDCTKQMQEYLSCIKLVKGENAPNCRLLAKEYLKCRMDNKLMDRDDWKHLGLPSDKKEANDVTKETTPTSGQ
What is the function of this protein?
Required for the assembly of mitochondrial cytochrome c oxidase.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX19.
What is the protein family that this protein belongs to?
Belongs to the COX19 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: HUTU_RHILO
Sequence: MMNNPRHNIREVRAPRGDKLNARYWTTEAPLRMLMNNLDPDVAENPNELVVYGGIGRAARTWNDFDRIVASLKTLGEDETLLVQSGKPVGVFRTHADAPRVLIANSNLVPHWATWEKFNELDKKGLMMYGQMTAGSWIYIGTQGIVQGTYETFVEAGRQHYGGNLKGKWILTGGLGGMGGAQPLAAVMAGACCLAIECNPDSIDFRLRTRYVDEKAETLDEAMEMIERWTKAGEAKSVGLLGNAAEIVPEMFRRGIRPDMVTDQTSAHDPINGYLPKGWTMAEWREKRVSDPKAVEKAARASMRDHVEAMVAFWNAGVPTLDYGNNIRQVAKDEGFENAFAFPGFVPAYIRPLFCRGIGPFRWAALSGDPEDIYKTDAKVRELTPGNTHLHNWLDMARERISFQGLPARICWVGLGDRHRLGLAFNEMVAKGELKAPVVIGRDHLDSGSVASPNRETEAMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVADGTPDAARRLERVLWNDPATGVMRHADAGYDIAIDCAKEHQLNLPGILG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TE2IP_XENLA
Sequence: MATLGGLTHSHTLFVEDDGTPVRFYIPPGPLKRQLYQLIIHGGGEMCRLQQPGALLLSTPGSAQGAQYVSTAYVMDCVRKGELLHVDDYRLDGSHGRKRQSKGMKQDEREGESSHGSDGKEQVKVGEGPEEEDELSDLGELVIEEGLEEDEQESDTVKIKKENKMDCSEAQKIGSLKSARIHQTGRNPFTEEEDVAILVYVRDNAPHRGTVTGIALWKEMEQRRVLKRTWQAIKDRYIKHLKGKQGYRLPLSAASRSHDPSEDESPQPITKKSRTNTSTPWTKRPGNIGRTSEKLGTALPMEKSSTKAPAEQSDAVESTSINFPLEKRGQHVTKGVVRRSEGEKKSSDMSKGAVSATSKEDQEDGGDLHIFEIANMEFEVDDTPEIELPKRSLSLREFVMGEDPPSSQSQTQVDEVSSSPEDSESEGLQEALLGMMSEFKLRLRDVTQALLKNNGELSATRHFLRTGSRPDGFPIWIRKDDLDLQKADAETQKRLIQKYGSDNVAKRVAFLAS
What is the function of this protein?
Acts both as a regulator of telomere function and as a transcription regulator.  Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome).  Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2.  Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression (By similarity).
What are the official names of this protein?
Telomeric repeat-binding factor 2-interacting protein 1, TERF2-interacting telomeric protein 1, TRF2-interacting telomeric protein 1, Repressor/activator protein 1 homolog, RAP1 homolog, XlRAP1.
What is the protein family that this protein belongs to?
Belongs to the RAP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: ATPG_BACFR
Sequence: MASLKEVKTRINSVQSTRKITSAMKMVASAKLHKAQGAIENMLPYQRKLNKILTNFLSADLPVESPFCVERPVMRVAIVAFSSNSSLCGAFNANVLKMFLQTVGEYRELGQDNILIYPVGKKIEEAVKKLGFFPQGSYQKLADKPSYDEAAALAKLLMELFLEKNIDRVELIYHHFKSMGVQELLRERYLPIDLSAVQNDEERGGVVNDYIIEPSAAQLIADLIPQVLSQKIFTAALDSNASEHAARTLAMQIATDNANELIQELTKQYNKTRQQAITNELLDIVGGSMA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VINT_BPL54
Sequence: MFRLEEKIKEKLNNKSSSELKTLTFHALLDEWLEYHIKTSGFKVTTLDNLKTRIKNIKKNSSQNLLLNKIDTKYMQTFINELSNVYSANQVKRQLGHMKEAIKYAVKFYNYPNEHILNSVTLPKKSKTIEDIEKEEAKMYNYLEMEQVIQIRDFILNDNNMQYRARILVAGAVEVQALTGMRIGELLALQVKDVDLKNKTIAINGTIHRIKCNAGFGHKDTTKTAGSKRKIAINSRIANVLKKIMLENKKMQQWEPSYVDRGFIFTTCQGNPMQGSRINKRLSSAAESLNINKKVTTHTLRHTHISLLAEMNISLKAIMKRVGHRDEKTTIKVYTHVTEKMDRELEQKLEKLVY
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.  It may bind the DNA.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: ILVC_BURP1
Sequence: MKVFYDKDADLSLIKGKQVTIIGYGSQGHAHALNLKDSGVNVTVGLRRGGASWSKAENAGLAVKEVAEAVKGADVVMMLLPDEQIAAVYAQEVHANIKEGAALAFAHGFNVHYGQVIPRADLDVIMVAPKAPGHTVRGTYAQGGGVPHLIAVAQDKSGAARDIALSYAAANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEETKKAMKQCLTDIQTGEYAKSFILENKAGAPTLQSRRRLTAEHQIEQVGSKLRAMMPWIAKNKLVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: OBG_PSEPG
Sequence: MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSVYMVADENLNTLVDYRYTRHHEAQRGSNGGSTDCTGKKGEDLFLRVPVGTTVIDASTQEVIGDLVTPGQKLMVAQGGWHGLGNTRFKSSTNRAPRQTTPGKPGDQRDLKMEMKVLADVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVIADIPGLIEGASEGAGLGIRFLKHLARTRVLLHLVDIAPLDESSPADAAEVIVNELTRFSPSLAERERWLVLNKSDMVMDDERDERVQEVIDRLEWEGPVYVISAISKQGTDKLSHDLMRYLEDRADRLANDPAYAEELADLDQRIEDEARAQLQALDDARTLRRTGVKSVHDIGDDDGWDDDFEDDEDGPEIIYVRD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPPK_PORG3
Sequence: MAIVYLSLGSNLGDRHSLLSAALEMLQTRVGRLLTLSRFYETEPWGFESPHPFLNAVVALRSELKPQDILHITQAIERELGRTQKSNGGVYHDRPIDIDILLHSVYPKVQSPELELPHPQMWQRDFVRMPLSDVAPWLHPEAPTPNL
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: RSMA_TRIV2
Sequence: MVRPRRVFAQHWLKSEKALDAIVKAAECSTNDRILEIGPGTGILTRRLLPLVEALLAVEIDRDLCKLLVKQLGQKENFLLLQGDFLTLDLVANLLTFPKFQKPNKVVANIPYNITGPIIEKLLGTIANPNPEPFDSIVLLIQKEVAERLYAKAGSRTFGALSVRVQYLADCEFICDVPAGAFHPPPKVDSAVVRLRPRQIQIPARDPKRLENLVKLGFGAKRKMLRNNLQSVVDRDRLSQLLEQLNINPQARAEDISTQQWVELANLLGVE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMRF2_EBVA8
Sequence: MFSCKQHLSLGACVFCLGLLASTPFIWCFVFANLLSLEIFSPWQTHVYRLGFPTACLMAVLWTLVPAKHAVRAVTPAIMLNIASALIFFSLRVYSTSTWVSAPCLFLANLPLLCLWPRLAIEIVYICPAIHQRFFELGLLLACTIFALSVVSRALEVSAVFMSPFFIFLALGSGSLAGARRNQIYTSGLERRRSIFCARGDHSVASLKETLHKCPWDLLAISALTVLVVCVMIVLHVHAEVFFGLSRYLPLFLCGAMASGGLYLGHSSIIACVMATLCTLSSVVVYFLHETLGPLGKTVLFISIFVYYFSGVAALSAAMRYKLKKFVNGPLVHLRVVYMCCFVFTFCEYLLVTFIKS
What is the function of this protein?
Facilitates virus attachment to oral epithelial cells by binding to host beta1 integrin family.  Participates in rearrangement of cellular actin to increase intercellular contacts by binding BDLF2 and thereby promote virus cell-to-cell spreading (By similarity).
What are the official names of this protein?
Protein BMRF2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BMRF2 family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host cell membrane. Note=In EBV-infected polarized oral epithelial cells, is transported to the basolateral membranes and colocalizes with beta1 integrin.
Protein: ARLY_SULNB
Sequence: MSKKIASARISEKSSKLLQDLNNSLPFDKVLYREDIEGSRAHAFMLSEQGIISREDQEKIDAGLQDILADIESGLFKLEGDDEDIHMAIEGELTRRIGDAGKRLHTARSRNDQVALDFRLYVQRNTKTIAELLLKNIETFVKVAEENAETMLPGMTHLQHAQPINFGYHMMAYASMFKRDYERFMSSYERNNYSPIGCAALAGTPHPINRQTTSDKLGFNAPTLNCLDTVSDRDFALEILFNISTVMMHMSRLSEELILWSAAEFKWVTLSDRHATGSSIMPQKKNPDIPELLRGKTGRVNGNLVALLTVMKSLPLAYNKDMQEDKEGVFDSVRTAILSLQVLEEMIADMTVNKEAMERACMVGHLSATDLADYLVKEQGLPFRDAYHITGNVVNLAEEKGLDISELSLEDLQSIDERIAEDVVALLDNRASMNARQSEGGTATVRTLEQIEDLKKWLEKQDEK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y114_BUCAP
Sequence: MKIEKMNFYSPKKYKWKGIKITEQAIEQILFLINKNPKNKGIRIGTKKSGCAGFRYTMELVKNNTIEKENKNDIVFYYNNILVYISLKEAPFLNGIKIDFVKDSINEVFKYCNPRIKTFCGCGESFSID
What are the official names of this protein?
Uncharacterized protein BUsg_114.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.