PharMolix/UniProtQA huggingface dataset:
Protein: MNME_ROSCS
Sequence: MMYDDTIAAIATPPGEGGIGIVRISGKDALSILERIFVPVRPGRWKPYRMRYGHVVDGAGVRVDEALAVFMRGPRSFTAEDTVEISVHGGPLVVERVLQQALAAGARAANPGEFTMRAFLNGRIDLTQAEATLDIITARTTTALALAEAQLGGWLSHELRRIRALLIDPLAYCTALVDFPEDEVEPQDVETPLTAAVQALDTLVATAEQGIIYRQGARATLVGRPNAGKSSLLNALLRIDRAIVTPIPGTTRDTLEETANLGGVPVVLTDTAGIVESVDPVERLGVERSRQAVAQADLLLLVVEGVSQPVDDDREIVALTRDKRTVLIVNKIDLIDGADAVQECMKFLKCAYENLRGVPFDATIAVSALTGQGLDMLGATVARLLLGDSSPADGRLVTNVRHRDALARAATHARDALDSFRRGVSPDLLAVDLTAAINAIGEVTGEAVGDDLLHAIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARRD3_PONAB
Sequence: MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAYTQNYTEEVEYFNHKDILIGHERDDDNSEEGFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPSLLSPQAGTKEKTLCCWFCTSGPISLSAKIERKGYTPGESIQIYAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEVKQLVANLRGESLSSGKTETWNGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGAMDLFLNLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLSLSLPERPEAPPSYAEVVTEEQRRNNLAPVSACDDFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSADDRPSCPSR
What is the function of this protein?
Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors.  Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation.  May recruit NEDD4 to ADRB2.  Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.
What are the official names of this protein?
Arrestin domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome. Endosome. Early endosome. Note=Associated with plasma membrane, as well as with endosomes and lysosomes during endocytosis.
Protein: TR14_HCMVA
Sequence: MRPQLRGNQRNRIRWWQHNSKKCNQTEKWHNVDWIHYEYPTHKMCELGNYHQTTPRHDICFDCNDTSLTIYNLTTRNAGKYTRHHRDNGQEENYYVTVLIGDTTLSTLGTCPVRYKESRNTENTIGSNIIKTIEKANIPLGIHAVWAGVVVSVALIALYMGSHRIPKKPHYTKLPKYDPDEFWTKA
What are the official names of this protein?
Protein TRL14.
What is the protein family that this protein belongs to?
Belongs to the RL11 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: SECB_RALPJ
Sequence: MSDQQQQQPGQDGQPFFNIQRVYLKDLSLEQPNSPHIFLEQEQPSVEVQVDVAASQLAEGVFEVTVIGTVTTKVQEKVAFLVEAKQAGIFDIRNVPAEQMDPLLGIACPTIVYPYLRSNIADTIGRAGFQPIHLAEINFQALYEQRLAAAMEQQGQAGGTGLVMPDGSKATH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_XANC5
Sequence: MTLWVLGLNHQTAPVDLRERAAFAGDALPRALESLRALPQVSEAALLSTCNRTELYAMADEAHSLVNWLETHAPGLSGHLYQHREAEAVRHLFRVATGLDSMVLGEPQILGQVKDAWAVARAHGALGSGLDRLFQQTFSVAKRARTDTRVGANPVSVASTAVRLAQDSFARLNESTVLLIGAGETIELAAKHLSEGRVRRLLIANRTLAHAQTLASQHGGFALPLTDLERHLAEADVVFSATAAREPLVTRAQVEQALRTRKRKPMLLFDLAVPRDIEASVGELGDAYLYTVDDLERAVEDNRRGRREAADQAEAIIDLQVARYVETLQATARQAPLKRLRAFGDSTRDELLAKARQQLHNGKPADEVLEQLAHALTNRLLHPPTAALRNAALNNDLELTTAADRLFPEKPGYQHPPIATPIVRTDDADPAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: TAGH_LISMO
Sequence: MDKNIKVSFKHVSKEYDLYQNKSDKIKGLFLPKSKRVQSFWALRNVCFDVYDGETVGLIGINGSGKSTISNIMSGVIPPTQGEVVINGETSLIAIAVGLKGPLSGLENIRLKLLMHGLKGSQIDSLLPSIIEFADIGDFINQPIKNYSSGMRSRLGFAISVHTDPDILVVDEALSVGDQTFYQKCVDKINEFKAQGKTIVFVSHSLGQVKSLCDKIIWMHHGEVREIGDAAEVAEKYDEFVKWFNKQPNDFKKKYQKEQKEKQKLPQEKIYPTPNANKYKMGLFDKCFLVVLLALLVLFGSLISTGKSFMGLFSATDNKVEQVTKVDKRTDWK
What is the function of this protein?
Part of the ABC transporter complex TagGH involved in teichoic acids export.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Teichoic acids export ATP-binding protein TagH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3.A.1.104.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATP8_HIPAM
Sequence: MPQLDTSTWFTTILSMFLTLFIIFQLKISKHTYHPNPETTLPMTQKQPTPWETKWTKIYSPLSLPLQS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: HCNB_PSEPH
Sequence: MSLNPVIVGGGPAGMAAAIELAEHGVRSTLIEEASRLGGVVYRGPLRDGVQLDYLGPRYCEMLAKLHGDFADHEQMIDVRLNSRVVGAEGTQSLVLLDGEEQVQQVSYEQLILAAGCHERSVPFPGWTLPGVKLLGGLQLQIKSGVVKPQSPVVIAGTGPLLPLVACQLHASGVRVAGVYEACALGKIAKQSLAMLNKPQLFLDGLSMLAYLKLHGIALRYGWGVVEAQGQDALSVVTVAPYSSDWQPDMAKAQRIAAQTLAVGYGFIPRTQLSQQMGLEHNFSDDGYLRASANAWQQSSEPHVHLAGDMGGIRGGEAAMLSGRIAALSILMQRGVLSNEAALQRRQGYERKLASILRFRGAVDRYTARGAGQVELPKGDTVICRCEHTTRNDIERALSQGVQDMASLKMRTRVSMGDCQGRMCVGYCSDRLRQATGRKDVGWIRPRFPLDPIPFSAFPPSDQEVSQHD
What is the function of this protein?
A three-component membrane-bound flavoenzyme that catalyzes the formation of hydrogen cyanide, a secondary metabolite, by transfer of electrons to a cyanide-resistant branch of the aerobic respiratory chain.  Contributes to suppression of black root rot of tobacco.
What are the official names of this protein?
Hydrogen cyanide synthase subunit HcnB, HcnB, Glycine dehydrogenase (cyanide-forming).
What are the subcellular locations of this protein?
Cell membrane.
Protein: PYRG_PSYCK
Sequence: MTKFIFVTGGVVSSLGKGITAASLAAVLEARGVNVTMTKMDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGYYERFLRHSKMSKSNNFTSGRIYQNVLNKERRGEYLGGTVQVIPHITDEIKSKILASGEGYDVAIIEIGGTVGDIESLPFMEAVRQMQVELGRNRAMLMHLTLVPYIASAGETKTKPTQHSVKELRSIGLQPDILICRSDHHISQDNRRKIALFTNVEERAVIMCEDAQSIYQIPRTLHEQDLDDLICERFGLDLPEADLSDWDKVVEAQLNPESTVTVAMVGKYVELPDAYKSINEALLHAGITHKADVKIDYIDAERLEDDDSLLAQLHNADAILVPGGFGERGTMGKIKAITYARENNVPYLGICLGMQLAVIEYARNVLHIDANSSEFDRKTAEPIIGLITEWLDERGELQIRSDDSDLGGTMRLGAQQAELVAGSKLAQIYGANNITERHRHRYEMNNRYIEPLEQAGMTVSGYSAKQHLVESVELADHPWFVAVQFHPEFTSSPRGGHPLFNSFVKAAKNYSEAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: Y8288_DICDI
Sequence: MNDEEFFSLLNQYPMRSDNPSTTTTQTSSQPNLFSIFNNMMGGMNRNQNQNQNQDQDQNQNQDKKDKEREFLVKLKQFLDNNVNNQEEADLIFTNFKKNHLKYIKENNLQ
What are the official names of this protein?
Putative uncharacterized protein DDB_G0289159.
Protein: MOT4_RAT
Sequence: MGGAVVDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQASGGAEPHGPQRPSPRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTKPEEVASEEEKLHKPPVDVRVDSREVEHFLKAEPEKNGEVVHTPETSV
What is the function of this protein?
Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate (PubMed:9632638, PubMed:10926847) (By similarity).  Plays a predominant role in the L-lactate efflux from highly glycolytic cells (PubMed:9632638, PubMed:10926847).
What are the official names of this protein?
Monocarboxylate transporter 4, MCT 4, Monocarboxylate transporter 3, MCT 3, Solute carrier family 16 member 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Plasma membrane localization is dependent upon the BSG/MCT4 interaction. Basolateral sorting signals (BLSS) in C- terminal cytoplasmic tail ensure its basolateral expression in polarised epithelial cells.
Protein: WHIA_LACJO
Sequence: MVSYASDVKKELTSLPVHPEHAKAELAAFLRMNGVLSLHDHQFSLDITTENPAIARRIFSLIKTAYGIEPLLIVSKKMKLKKNYQYLVRLQKQVHEILTDLEIFDSNNGLITGIPEKIMSSEQRAMSYLRGAFLASGSVNNPETSRYHLEIYSLYEDHNQDLLKLMNNFFYLNAKETRRRSGYIVYLKEAEKIGDFLHIVGAVNAMLAFEDLRIMRDMRNSVNRLVNCDTANLKKTANAAAKQVEDIQLIEEKFGLENLPEKLTVLARFRLTHPELSLKEVAAQVPDGPISKSGVNHRFQKIREIAKQLKEEN
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: LSPA_STRPG
Sequence: MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMIHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYSG_PSEFS
Sequence: MEFLPLFHNLRGSRVLVVGGGEIALRKSRLLADAGAVLRVVAPQIEDQLRELVQGSGGELMLRGYQEADLDGCTLIIAATDDEPLNAQVSSDAKRRCVPVNVVDAPALCSVIFPAIVDRSPLVIAVSSGGDAPVLARLIRAKLETWIPSTYGQLAGLAARFRAQVKGLYPDVQQRRAFWEEVFQGPIADRQLAGQGDEAERLLIEKVNGAPPYAPGEVYLVGAGPGDPDLLTFRALRLMQQADVVLYDRLVAPAILELCRRDAERIYVGKRRADHAVPQDQINQQLVDLAKQGKRVLRLKGGDPFIFGRGGEEIEELAAHGIPFQVVPGITAASGCAAYAGIPLTHRDYAQSVRFITGHLKNGTSDLPWQDLVGPSQTLVFYMGLIGLPIICEQLIKHGRAADTPAALIQQGTTSNQRVFTGTLADLPRMVAEHEVHAPTLVIVGEVVVLREKLKWFEGAQSQV
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: RAD50_THEKO
Sequence: MKIEKLIIKDFRSHALTKVNFSSGINLIIGQNGSGKSSILDALLVGLYWPSKPKDLKKDDFERINGSGTEITVFFEKGNVKYQIHRNIGRGLAFVKYHDGSSWKTLETGQKPVRDWMEKLVPYDVFLNAIYIRQGEIDAILESDESREKVVRQVLGLDRYENSYKNLLDVRKEIDARIKAIEDYLKSTENIDELIGNLEKELTSVLREINEISPKLPELRGELGGLEKELKELEKTAEELAKARVELKSEEGNLRELEAKKSGIQSMIRETEKRVEELKEKVKELESLEEKAKEYERLSRFYRNFTEGINRIEKLLATYSQQAENLRERIDELSKKEARVKELLKEKEGLQKELGALEEDLKAYQRAKELMANLERLKKRLTLSEEEIEKLEAEIQKARERKEEIMKELEEIGSRRGELKSIAGERNKALMELKKAKGRCPVCGRELTEEHRKELLEKYTAELKEISAEMKELEKREKKLRAELVEVEKTLKKERELFALKEVLEQIRETEEKLKEYDLEKLEEANEKAEELKKKLAGLEGEIKSLEDEIKKGELLKKKLALVEKKLRELEEERASLLGELKKLGFGDVKELEERLKELEPAYKRYIELRPARDELKREEDLLKSLKLDLTAILKEIEKTSKRVEELRKRVEELEKSYDKDRHEELKGKTRELSNELAGLEARLKSLEERRDEVKASLEKLREEKETRKEKAKELEKLKKARERVQRLREKVKAYKNLLKEGALAKVGEMASEIFEELTEEKYSGVTVKAEENKVRLGVVYNGKEYGLGFLSGGERIALGLAFRLALSLYLAGEISLLILDEPTPYLDEERRRRLVDIMQRYLRKIPQVIVVSHDEELKDAADRVIRVSLENGVSVVREAEVG
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
What are the official names of this protein?
DNA double-strand break repair Rad50 ATPase.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
Protein: Y048_HELAH
Sequence: MDFSQLSGLLDGVKKEFSQLEEKNKDTIYTSKSGGGMVSVSFNGVGELVDLQIDDSLLEDKEAMQIYLMSALNDGYKSVEENRKNLAFSMLGNFAKL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Hac_0048.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TTPAL_HUMAN
Sequence: MSEESDSLRTSPSVASLSENELPPPPEPPGYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRSWPEVFNNLKPSALKDVLASGFLTVLPHTDPRGCHVVCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRSILPKEYGGTAGELDTATWNAVLLASEDDFVKEFCQPVPACDSILGQTLLPEGLTSDAQCDDSLRAVKSQLYSCY
What is the function of this protein?
May act as a protein that binds a hydrophobic ligand.
What are the official names of this protein?
Alpha-tocopherol transfer protein-like.
Protein: PABP3_HUMAN
Sequence: MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLESPESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV
What is the function of this protein?
Binds the poly(A) tail of mRNA.  May be involved in cytoplasmic regulatory processes of mRNA metabolism.  Binds poly(A) with a slightly lower affinity as compared to PABPC1.
What are the official names of this protein?
Polyadenylate-binding protein 3, PABP-3, Poly(A)-binding protein 3, Testis-specific poly(A)-binding protein.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_STRP6
Sequence: MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNYIRILVGDRVTVEMSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORA_CORRG
Sequence: MKKVVSSLLIILGAAMLIFAIALPTYVVPKGKVLPKDIVSTTGTDPIKGNLLDASALAEGKPVSGKENLPECRGKDKQVSCFIWKDLELQSQRFTRAQEPTDDKVVTLEAGQTLFRTDRQEPKNLVNATVDRVTLDRKTQMPVADPVSTLDVNAPALNPNGEAAIGPFTRPGIQYQFPMGTDRRSYDYFDTQALKAQPIDYVGEEEQDGEKVYKFEQTVSPVELYPRLKEQLEADGDLSKADQSTLASLRLKFPAKVWGIEGADTKSAADSKDDKKKDGDKKDEKSPEVELSRYYTVKRTLWVQPDTGVIVNGKEDIWQFYAKDQDEADKMAQPENREKEMNNPKRTALYIPGAWNDESRAAQMDKAKEGLKTLKTMGTTVPWILGPLGLLLLLVGLVMALKRRRAERHANAL
What is the function of this protein?
Forms water-filled channels that favor the permeation of cations.
What are the official names of this protein?
Porin PorA.
What is the protein family that this protein belongs to?
Belongs to the PorA family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Probably part of the corynemycolate layer which forms a structure similar to the outer membrane found in Gram-negative bacteria.
Protein: Y930_TREPA
Sequence: MRFPSMGTSDVAGVRGDVPSLPPRLIKTQNGFTVLYRNTYLYSKYRAQDAHERAVARLAVKPHTLVLCCAPVLGHGLCALLTRMPPSSFLLCLECDLQLMHLFMQHAPRQLITAQNVYVLYTTHITQVLHTVERLTRFPFKQILKIAGSGAYAQYRNFYDESEQNIRTLIDTFWINKITLIHSGRNYARNIFSNYITQLQNPSHIHHLVPQSIDKPLLIVGAGPALDACRSFCARMKDTIFLLAVDVACNALLPDIVPDAVVLLESQFWIEQAFIGTLPRTVALFADLSAFPRAVRAANVPTHFFFTPYTHAAFIKRAQNAGVVPLSIHPSGSVGLAALQLALRLRKKGVPIFHTGLNFSWNKGFTHARGSAPVQRLYHSTTRLHSLYPDCALFPEGIRSLKGKRYAVQSIPNLVHYAHAYRTLCAEHPHLYDLDQEGLALTTSHTVSHAQACEIITHCCTRRHRTHVPILHTQDAQISFAFSQKPAEDFCLRVKELLTTERAALLQLKHMLTTATPSNQDVIRALIRRSDYLYLHFPDGERAEYLEYNFLCRVRAELDFFLKLLSRIPSSLD
What are the official names of this protein?
Uncharacterized protein TP_0930.
Protein: COAA_STRT2
Sequence: MLNEFINFETISRSDWQRFYQEDQVSLTPEELESIRSLNDKIDVQEVRDIYLPLINLIRIYHRAAEDLTFSKGIFLQKAQANRPFIIGISGSVAVGKSTTSRLLQLLLQRTFPKAKVDMVTTDGFLFPNQVLIDKGILNRKGFPESYDMPLLLNFLDTVKNGGDVNIPVYSHEIYDIVPGLTQKISQPNFLIVEGINVFQNPINQRLYMSDYFDFSIYIDADVKNIKTWYLERFQTLLELARKDENNYYHRFTKFTKEEALSLAQKTWKEINLVNLENYIEPTRNRAELILHKGDSHKIDLIHLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMRA_BACSU
Sequence: MPTKKQKSKSKLKPFFALVRRTNPSYGKLAFALALSVVTTLVSLLIPLLTKQLVDGFSMSNLSGTQIGLIALVFFVQAGLSAYATYALNYNGQKIISGLRELLWKKLIKLPVSYFDTNASGETVSRVTNDTMVVKELITTHISGFITGIISVIGSLTILFIMNWKLTLLVLVVVPLAALILVPIGRKMFSISRETQDETARFTGLLNQILPEIRLVKASNAEDVEYGRGKMGISSLFKLGVREAKVQSLVGPLISLVLMAALVAVIGYGGMQVSSGELTAGALVAFILYLFQIIMPMGQITTFFTQLQKSIGATERMIEILAEEEEDTVTGKQIENAHLPIQLDRVSFGYKPDQLILKEVSAVIEAGKVTAIVGPSGGGKTTLFKLLERFYSPTAGTIRLGDEPVDTYSLESWREHIGYVSQESPLMSGTIRENICYGLERDVTDAEIEKAAEMAYALNFIKELPNQFDTEVGERGIMLSGGQRQRIAIARALLRNPSILMLDEATSSLDSQSEKSVQQALEVLMEGRTTIVIAHRLSTVVDADQLLFVEKGEITGRGTHHELMASHGLYRDFAEQQLKMNADLENKAG
What is the function of this protein?
An efflux transporter able to transport Hoechst 33342, ethidium bromide, doxorubicin and a number of other drugs in vitro into inside out vesicles.  The endogenous substrate is unknown.  It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation (PubMed:18215075).  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable).
What are the official names of this protein?
Multidrug resistance ABC transporter ATP-binding/permease protein BmrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERYH_RHIME
Sequence: MSKSGLWVGTSWKMNKTLAEAMVFADGLAAADDARDQRIQRFVIPPFTAARQVKERLKATSVKVGAQNMHWDDAGAWTGEISPVMLSDCDLDIVELGHSERREHFGETDRTVGLKTAAAVKHGLVPLICIGETLAQREAGEADTVLKRQVEGAFAFLEGAARKAPVLLAYEPVWAIGVNGIPATADYADARHRLIGEVAERALGVKVPVLYGGSVNPQNCEELILQPHIDGLFIGRSAWDVGGYLDILQRVARAI
What is the function of this protein?
Catalyzes the isomerization of D-erythrulose-4P to L-erythrulose-1P.
What are the official names of this protein?
L-erythrulose-1-phosphate isomerase, D-3-tetrulose-4-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACA2_MOUSE
Sequence: MLESIRVTEKLHWPEHELAKKFVLNAEEALITDSKRSFSSLSSGILKDTFTTGTSSYNVLLQSKEEKKHRSQKRFSSASSKQHRKPSKSPSSSHSKDPSRMTALVPGTGAGTWYCLDGQSAVFVTSSVPSPVKFTRDISITGSGLALPPKPKSKVKRRNLTRLPKPKQQPQLCRSFERGDDISGKKLCILTAIKPINLEKEKLRFFKSDYTYNPQFEYANPTLPGVLAKHSNASDRFLKQSINIMELTLQKYGSYEKFEQATGGSLLSKTRIWSHVRKYMVKEGCLGEIVVHLTEDLLSRASMTVVNGCPTLTINISTAREHWLEGMLRHEIGTHYFRGINNLQQPWNSWIGRKKHELKPNNPTEEGLASIHSVLFRKDPFLWRAALLYYTVYKASHMSFCELFKDIGKFVKDPNTRWDYCVRAKRGWTDTSEPGCFSKDQVYLDGVLQILRFRESIDFHLLTALGKVSYEDVDRLKELAVTENMRVPHFLHDHSRYMEHLERIMEVNELTDAELKNLI
What is the function of this protein?
Putative tyrosine carboxypeptidase.
What are the official names of this protein?
Putative tyrosine carboxypeptidase MATCAP2.
Protein: HMDH_MAIZE
Sequence: MEVRGGVGQGSAARHPPAPEPSRAAARVQAGDALPLPIRHTNLIFSALFAASLAYLMRRWREKIRSSTPLHAVGLAEMLAIFGLVASLIYLLSFFGIAFVQSIVSSGDDDEDFLVGSGSSGSAAAPSRQHAQAPAPCELLGSPAAAPEKMPEDDEEIVASVVAGKVPSYALEARLGDCRRAAGIRREALRRITGRDIEGLPLDGFDYASILGQCCELPVGYVQLPVGVAGPLLLDGRRFYLPMATTEGCLVASTNRGCKAIAESGGATSVVLRDAMTRAPVARFPTARRAAELKAFLEDPANFDTLSVVFNRSSRFARLQGVQCAMAGRNLYMRFSCSTGDAMGMNMVSKGVQNVLDFLQDDFHDMDVISISGNFCSDKKPSAVNWIEGRGKSVVCEAVIGEEVVKKVLKTDVQSLVELNTIKNLAGSAVAGALGGFNAHASNIVTAIFIATGQDPAQNVESSHCITMLEPVNAGRDLHISVTMPSIEVGTVGGGTQLASQSACLDLLGVRGASRDRPGSNARLLATVVAGGVLAGELSLLSALAAGQLVKSHMKYNRSSKDVSSTTATEKTRQREVDV
What is the function of this protein?
Catalyzes the synthesis of mevalonate.  The specific precursor of all isoprenoid compounds present in plants.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL24_STUS1
Sequence: MQKIRRNDEIIVIAGKDKGKRGKVLKVLADDRLVVGGINLVKRHTKPNPMSGVQGGIVEKEAPLHVSNVAIFNGETNKADRVGFKVEEGKKIRVFKSTQKPVDA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.