PharMolix/UniProtQA huggingface dataset:
Protein: OPA1_PONAB
Sequence: MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHYPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPNSEDLVKLAPDFDKIVESLSLLKDFFTSGSPGETAFRATDHGSESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQATPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQGEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
What is the function of this protein?
Dynamin-like 120 kDa protein, form S2: Produced by cleavage at position S2 by YME1L.  Promotes mitochondrial fusion.
What are the official names of this protein?
Dynamin-like 120 kDa protein, mitochondrial, Optic atrophy protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space. Mitochondrion membrane. Note=Detected at contact sites between endoplasmic reticulum and mitochondrion membranes.
Protein: MNMA_NEIMB
Sequence: MNTTANPSNIIVGLSGGVDSSVTAALLKQQGYQVRGVFMQNWEDDDNDEYCSIKQDSFDAIAVADIIGIDIDIVNFAAQYKDKVFAYFLQEYSAGRTPNPDVLCNAEIKFKCFLDYAVGQGADTIATGHYARKEVRNGVHYLLKGLDRNKDQSYFLYRLKPFQLERAIFPLGGLEKPEVRRLAAEFKLPTAAKKDSTGICFIGERPFREFLQKYLPTDNGKMVTPEGKTVGEHVGLMFYTLGQRKGLGIGGAGEPWFVAAKDLTKNELIVVQGHDHPLLYTRSLVMNDLSFTLPERPKAGRYTCKTRYRMADAPCELRYLDDETAELVFDEPQWAVTPGQSAVLYDGDICLGGGIIQTTDKPVIITR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TVP18_PICST
Sequence: MAFSIQSIFSNIFSGLSADFKKKNFSLYGQWVGIISILLCLALGVANIFHASIVIVFSIICIVQGLVVTLVEMPFLLKICPFTETFTNFIKNFDANWPRCGFYLLNAAIQWVSIAVMATSLIVVACFFTVAGGCYALAAITHQEYLKSSIQVTGSPDSVEGQIGQHVVRNVL
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP18.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: VIRF2_HHV8P
Sequence: MPRYTESEWLTDFIIDALDSGRFWGVGWLDEQKRIFTVPGRNRRERMPEGFDDFYEAFLEERRRHGLPEIPETETGLGCFGRLLRTANRARQERPFTIYKGKMKLNRWIMTPRPYKGCEGCLVYLTQEPAMKNMLKALFGIYPHDDKHREKALRRSLRKKAQREAARKQAAAVATPTTSSAAEVSSRSQSEDTESSDSENELWVGAQGFVGRDMHSLFFEEPEPSGFGSSGQSSSLLAPDSPRPSTSQVQGPLHVHTPTDLCLPTGGLPSPVIFPHETQGLLAPPAGQSQTPFSPEGPVPSHVSGLDDCLPMVDHIEGCLLDLLSDVGQELPDLGDLGELLCETASPQGPMQSEGGEEGSTESVSVLPATHPLESSAPGASVMGSGQELPDLGDLSELLCETASPQGPMQSEGGEEGSTESVSVLPATHPLESSAPGASVMGSSFQASDNVDDFIDCIPPLCRDDRDVEDQEKADQTFYWYGSDMRPKVLTATQSVAAYLSKKQAIYKVGDKLVPLVVEVYYFGEKVKTHFDLTGGIVICSQVPEASPEHICQTVPPYKCLLPRTAHCSVDANRTLEQTLDRFSMGVVAIGTNMGIFLKGLLEYPAYFVGNASRRRIGKCRPLSHRHEIQQAFDVERHNREPEGSRYASLFLGRRPSPEYDWDHYPVILHIYLAPFYHRD
What is the function of this protein?
DNA-binding transcription factor that plays a role in the modulation of host immune response (PubMed:26537687, PubMed:31059555).  Acts by interacting with host EIF2AK2/PKR and inhibiting its activation.  In turn, EIF2AK2/PKR substrates including EIF2S1 or histone H2A are not phosphorylated (PubMed:11160738).  Inhibits type I interferon signaling by targeting host IRF3 during viral reactivation from latency (PubMed:11160738, PubMed:21697347).  Attenuates the transcriptional activity of host FOXO3 via activation of the AKT1 signaling pathway, inhibiting FOXO3-mediated apoptosis (PubMed:26797279).  Suppresses also the expression of viral early lytic genes in both newly infected and reactivated infected host cells allowing regulation of viral life cycle by harnessing the interferon pathway.  Mechanistically, promotes host PML bodies formation as well as host antiviral restriction factors IFIT1-3 expression leading to inhibition of viral early lytic proteins (PubMed:31059555).  Regulates also host TRAF3 and TRAF6 ubiquitination by interacting with USP7 deubiquitinase thereby influencing TRAF3/6-mediated signal transduction (PubMed:31666375).
What are the official names of this protein?
Viral IRF2-like protein, vIRF-2.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: RL17_HUMAN
Sequence: MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:32669547).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:32669547).
What are the official names of this protein?
60S ribosomal protein L17, 60S ribosomal protein L23, Large ribosomal subunit protein uL22, PD-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_GEOSW
Sequence: MSRISIEQVKHVAHLARLAITDEEAEMFTKQLDAIITFAEQLNELDTENVPPTSHVLDMKNVMREDVPTPGLPLEEVLKNAPDHQDGQFRVPAILE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: X_HBVA9
Sequence: MAARLYCQLDSSRNVLCLRPVGAESCGRPLSGPVGTLSSPSPSAVPTDHGAHLSLRGLPVCAFSSAGPCALRFTSARCMETTVNAHQILPKVLYKRTLGLPAMSTTDLEAYFKDCVFKDWEELGEEIRLKIFVLGGCRHKLVCAPFSCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: RUXF_NEUCR
Sequence: MSFVPVNPRPFLQDLVNSFVTIRLKWGETEYVGRLVSIDSYMNIQLSDTKEYINRKFTGALGQVLIRCNNVLYIKKADEAETSGDVKMEE
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
What are the official names of this protein?
Probable small nuclear ribonucleoprotein F, snRNP-F, Sm protein F, Sm-F, SmF.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CML2_HUMAN
Sequence: MEDLEETLFEEFENYSYDLDYYSLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSLIVIIFIWLLASLIGGPALYFRDTVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFIIGYLFPLLTMSICYLCLIFKVKKRSILISSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAEILKYTLWEVSCSGTVSEQLRNSETKNLCLLETAQ
What is the function of this protein?
(Microbial infection) Coreceptor for HIV-1.
What are the official names of this protein?
Chemerin-like receptor 2, Chemerin chemokine-like receptor 2, Chemokine-like receptor 2, G-protein coupled receptor 1.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like receptor (CMKLR) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Internalizes in presence of its ligand, TAFA1 (By similarity). Internalizes efficiently in response to RARRES2 (PubMed:27716822).
Protein: KPRS_STAAS
Sequence: MLNNEYKNSSLKIFSLKGNEALAQEVADQVGIELGKCSVKRFSDGEIQINIEESIRGCDVFIIQPTSYPVNLHLMELLIMIDACKRASAATINIVVPYYGYARQDRKARSREPITAKLVANLIETAGATRMIALDLHAPQIQGFFDIPIDHLMGVPILAKHFKDDPNINPEECVVVSPDHGGVTRARKLADILKTPIAIIDKRRPRPNVAEVMNIVGEIEGRTAIIIDDIIDTAGTITLAAQALKDKGAKEVYACCTHPVLSGPAKERIENSAIKELIVTNSIHLDEDRKPSNTKELSVAGLIAQAIIRVYERESVSVLFD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STUS1
Sequence: MSKSLQAIRGMNDILPAQTPTWRYLESTFAQLLESYGYSEIRLPILEFTDLFARGIGEGTDVVDKEMYTFLDRNEESLTLRPEGTAGCVRAVLEHGMTGGGQVQKLWYTGPMFRYEKPQKGRYRQFHQIGVEVFNQPGPDIDAELIVLTARLWKQLGLADAVTLQLNSLGSSEARARYRDALVAYLQQRFEQLDEDSQRRLTTNPLRILDSKNAQTQALLTDAPTLHDYLDEESRAHFEGLKARLDAVGIAYEINPKLVRGLDYYGRTVFEWVTDKLGAQGTVCAGGRYDGLVSQFGGKPTPGVGFAMGVERLVLLLETLGLVPETLNPAPHAYICAFGEAAELAALALAERLRDELPGLRLLVNAGGGSFKSQFKKADKSGARYALILGDDELAGRVVGCKPLRDDSEQQSIAWDALPERLAACLEQV
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: MECA_EXIS2
Sequence: MKIERVNDNTVKFFITYTDIERRGFARDEIWYNRERGEQLFWQMMDEANEKESISFEGPLWIQVQAFEKGLEVTVTIAKTTIDGEQVDEDELDSLLRSAMSDAEEKETELSQDVLFETTDFEHIIALSQYAEAPIFEEVKTSLYQKDGLYLLHLHFKEETEVEEQENVMSLIAEYLNFSEQTIHPVAEYGKVIVPNDVFAFIRKHFPN
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: ANKE1_HUMAN
Sequence: MALADKRLENLQIYKVLQCVRNKDKKQIEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRAERIANKLARPGAKNPNPLWALRLHDWSVEREAFLREAFAVLDRGDGSISKNDFVMVLEERQDYASSEQLAAIAHLHEKTRGGGVNINEFFKGTRYLNKSFVLGSYGPKKKEKGMGKKGKKGKFVLPLPICVIPEYAFPRRQDGGPPYYMIETYKNVTDSSRFNRDHPPEHPIQDDSVWYIDDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKGKTPPILKTEGPEIKKEEELLSSIYGVPTTSEGKKVQKGNVVHLNSLITSGYTKKVDITFIPRRIWSPEATTAELIRKRELRRERFTHEVDFDDFMMPFQKNITEKARALEAALKT
What are the official names of this protein?
Ankyrin repeat and EF-hand domain-containing protein 1, Ankyrin repeat domain-containing protein 5.
Protein: PPDK_CLOSY
Sequence: MAKWVYKFEEGNASMRNLLGGKGCNLAEMTILGMPIPQGFTVTTEACTEYYNSGKQITQEIQDQIFEAITWLEELNGKKFGDTEDPLLVSVRSGARASMPGMMDTILNLGLNDVAVEGFAKKTGNPRFAYDSYRRFIQMYSDVVMEVPKSHFEKIIDAMKEEKGVHFDTDLTADDLKELAEKFKAVYKEAMNGEEFPQEPKDQLMGAVKAVFRSWDNPRAIVYRRMNDIPGDWGTAVNVQTMVFGNKGETSGTGVAFTRNPSTGEKGIYGEYLINAQGEDVVAGVRTPQPITQLENDMPDCYKQFMDLAMKLEKHFRDMQDMEFTIEEGKLYFLQTRNGKRTAPAALQIACDLVDEGMITEEEAVVRIEAKSLDQLLHPTFNPAALKAGEVIGSALPASPGAAAGKVYFTADEAKAAHEKGERVILVRLETSPEDIEGMHAAEGILTVRGGMTSHAAVVARGMGTCCVSGCGEIKINEEAKTFELGGHTFAEGDYISLDGSTGKIYKGDIETQEASVSGSFERIMVWADKFRTLKVRTNADTPEDTLNAVKLGAEGIGLCRTEHMFFEADRIMKIRKMILSDSVEAREEALNELIPFQKGDFKAMYKALEGRPMTVRYLDPPLHEFVPHTEEEQAELAKNMGLTLAEVKAKVDELHEFNPMMGHRGCRLAVTYPEIAKMQTRAVMEAAIEVKEETGIDIVPEIMIPLVGEKKELKFVKDVVVEVAEQVKKEKGSDMQYHIGTMIEIPRAALTADAIAEEAEFFSFGTNDLTQMTFGFSRDDAGKFLDSYYKAKIYESDPFARLDQTGVGQLVEMAVKKGRQTRPGLKCGICGEHGGDPSSVEFCHKVGLNYVSCSPFRVPIARLAAAQAALNNK
What is the function of this protein?
Catalyzes the reversible phosphorylation of pyruvate and phosphate.  In E. histolytica and C. symbiosus, PPDK functions in the direction of ATP synthesis.
What are the official names of this protein?
Pyruvate, phosphate dikinase, Pyruvate, orthophosphate dikinase.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: RBSD_ACTSZ
Sequence: MKKTTIINAQLSYAIATLGHTETLTLCDAGLPIPNSSNRIDLALTKGIPSFLETLYAVTSEMFVERAILASEIKEKNPEILTALLAHLSQLATKQGNQIPVEFVSHEKFKKLTHDSKGIVRSGECSPYANIILVSGVPF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RACM_DICDI
Sequence: MNIKTIKIVTIGDYGVGKTTLLMTYTASGSFPQEYVPTALDNFIHEATINGKKASLSIWDTAGGEYYHELRPLIYPETDILLLLFAIENRESFLHIKTNWITEINQYIPGIPIILVGTKIDLRDSDLIKDKSNFVKYKEGLALSKEIGASHFCECSSRMNLGLEELFKKVIKLTNNNNNNNNNNKCIIL
What are the official names of this protein?
Rho-related protein racM.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: TRMD_ALCBS
Sequence: MMTTKPTFAVTLVTLFPEMAQAITGFGVTRRAVDNGQLQVETVNPRDFTEDRHRTVDDRPFGGGPGMVMKVEPLAKALQAARVANPAAKVIYLSPQGQPLTQAKATALAEQPGLILLAGRYEGVDERLLDAEVDEQISIGDYVLSGGELPALVLIDAVSRLIPGVLGHQDSAEQDSFSGEFENLLDCPHYTRPEVYGEQAVPPVLLSGNHELIRRWRLKQALGRTWQQRPDLLEARRARGLSKEEQQLLDEYIAEQPSHTAKTTD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VWA7_BOVIN
Sequence: MLPADVPLCHLGPSVLLLLQLLLPSASAFFPNIWSLLAAPGSITHQDLTEEAALNVTLHLFLEQPPPGRPPLRLEDFLGRTLLADDLFAAYFGPGSPSRRFRAALGEVSRANAAQDFLPTSKNDPDLHFDAERLGQGRTRLVEALRETVAAAKALDYTLARQRLGAALHALQDFYSHSNWVELGRQQPHPHLLWPRQELRSLAQAGDPTCSDCEELSCPGNLLGFTLLTSGYFGTRPSKPPGKCSHGGHFDQSSSQPPRGGINKDSTSPGFSPHHMLHLQAAKLALLASIQAFNLLQSRLGDRGFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARHIVEQRRGTPMEPTQYVLVPFHDPGFGPVFTTSDPDSFWQQLNEMHALGGGDEPEMCLSALELALLHTPPLSDIFVFTDASPKDAFLTNRVESLTQERRCRVTFLVTEDPSRAQGRARREVLSPLRFEPYEAVALASGGEVIFTEDQYIQDVAAIVGDSIADLVTLPLEPRVVVAERPLVFRVDGLLQKVTVRIHGEVSSFWIRNPAGVSQGQEEGEGPLGHTHRFGRFWMVRVNDPPQSGTWEIQVTAKGTPRVRVQAQTSLDFLFHFGIPMEDGPHPGLYPLTQPVAGLQTQLLVEVTGLGSRGGPGGPLPHFSHVVLRGVPQGAELGQVPLEPRGPPERGLLAASLPPTLLSTSGPFSLELVGQDGVGRGLHRAAPQPCAVVPVLLELSGPRGFLAPGTTAPLSLRIASFSGPQDLHLRTSAKPSFALTSNLSRVHLEQNEAAWGRLWLEVPDTAASDSVVMVTVTAKNGEASTMPPTHAFLRLLVQAPAPQDQLPAPAYSTDPVLNTSRPAFHFFTSVTQGGAGGGLVGNPWWTTFGVMLLLLGLGPW
What are the official names of this protein?
von Willebrand factor A domain-containing protein 7, Protein G7c.
What are the subcellular locations of this protein?
Secreted.
Protein: RL6_METRJ
Sequence: MSRVGKKPVPVPAGVTATVTGQTVKMKGSKGELSFVVPALVNVAMKDGAIEVQPVNQSKPARSLWGTSRAQIANIAEGVSKGFEKKLEITGVGYRAAMAGKALKLSLGYSHDIEYAIPAGITIATPKPTEITISGINRQQVGQVAAEIREYRGPEPYKGKGVKYAGEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HACD_CAEEL
Sequence: MSVQTYLVAYNVLQILGWSAILVKTVLGLANGLTWPQLYESVEFELKIFQTAAILEVIHAIVGLVRSPVGTTAMQVTSRVVLVWPILHLCSTARFSIGVPLLLVAWSVTEVIRYSFYALSVLKQPIPYFLLYLRYTLFYVLYPMGVSGELLTLFASLNEVDEKKILTLEMPNRLNMGISFWWVLIIAALSYIPGFPQLYFYMIGQRKKILGGGSKKKQ
What is the function of this protein?
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation.  Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase hpo-8, Probable 3-hydroxyacyl-CoA dehydratase.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EX7L_PSEF5
Sequence: MIKDPFARLGLDREVLTVTQLNGRARVLLEDVFSNIWVEGEISNLARPASGHVYFTLKDSGAQVRCALFRQNAARVRQALKDGLAVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKDKLSAEGLFSAERKVPLPAHPQRIGIISSPTGAVIRDIISVFRRRAPQVVLTLIPTAVQGREATAQIVRALQLADARGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDSSDLQRRVDNLHRRLVMRMRDRLVRDRLRLDGLARRLRHPGERLRQQAQRLDDLDMRLRRAFERSLNTRRERLIRLETRLGAQHPGRQLALLRQRLDSLAERLPRAMREGLKGRRLQLHSQMQTLHVVSPLATLGRGYSILLDDRGQAIRSAGQTRPGQRLSARLGEGELQVRVEDNHLTPVTLSLLD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_THESQ
Sequence: MTIDEIIEAIEKLTVSELAELVKKLEDKFGVTAAAPVAVAAAPVAGAAAGAAQEEKTEFDVVLKSFGQNKIQVIKVVREITGLGLKEAKDLVEKAGSPDAIIKSGVPKQEAEDIKKKLEEAGAEVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: COBQ_HALHL
Sequence: MVRARTLMLQGTCSGAGKTALVAGLCRLLARHGVRVAPFKPQNMSNNAAVTADGGEIGRGQWLQALAAGLPAHTDMNPVLLKPEAERTAQVVVQGHVTGRLEARAFREARQPLLPPVLESFQRLCAAYDVVLVEGAGSPAEPNLRQGDIANMGFAEAADVPVWLVGDIDRGGVFASLLGTLEWLDDADRRRVEALIINRFRGSPELLGEAPAQLEARGGVPVIGVVPAVPDLHLPEEDAPYRMAGPRGSGGALQVVAVAYPRMSNHDDLDALDAESGVHVRFARQPRELDGADLIVLPGSKHVFSDLAWLRESGMAEALYRHCRYGGRVVGLCGGLQMLGEGIEDPEGVEGGGSAPGLGLLPVHTRLAPTKQLAEVHGHAEWPAPVAVTGYEIHHGVTGAQEGLFPFVARSDDGRVLGSYLHRLFDSGPFRRALLVEWFALEGEGGDEQARIEAELDRLADTLEQALEPGWLKALGVPARPST
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: ABGA_ECOLI
Sequence: MESLNQFVNSLAPKLSHWRRDFHHYAESGWVEFRTATLVAEELHQLGYSLALGREVVNESSRMGLPDEFTLQREFERARQQGALAQWIAAFEGGFTGIVATLDTGRPGPVMAFRVDMDALDLSEEQDVSHRPYRDGFASCNAGMMHACGHDGHTAIGLGLAHTLKQFESGLHGVIKLIFQPAEEGTRGARAMVDAGVVDDVDYFTAVHIGTGVPAGTVVCGSDNFMATTKFDAHFTGTAAHAGAKPEDGHNALLAAAQATLALHAIAPHSEGASRVNVGVMQAGSGRNVVPASALLKVETRGASDVINQYVFDRAQQAIQGAATMYGVGVETRLMGAATASSPSPQWVAWLQSQAAQVAGVNQAIERVEAPAGSEDATLMMARVQQHQGQASYVVFGTQLAAGHHNEKFDFDEQVLAIAVETLARTALNFPWTRGI
What is the function of this protein?
Component of the p-aminobenzoyl-glutamate hydrolase multicomponent enzyme system which catalyzes the cleavage of p-aminobenzoyl-glutamate (PABA-GLU) to form p-aminobenzoate (PABA) and glutamate.  AbgAB does not degrade dipeptides and the physiological role of abgABT should be clarified.
What are the official names of this protein?
p-aminobenzoyl-glutamate hydrolase subunit A, PABA-GLU hydrolase, PGH.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: TUXA_POLAB
Sequence: RKRLFYRYYSHPGNYMYLGHYGRYYNMLHNCNAMLLAHQMQAMRRYQHRMRVKQMYRRIKMKQMYRHMKWMGMYRQAKAARLRCI
What is the function of this protein?
Is lethal to drosophila larvae.
What are the official names of this protein?
Turripeptide PaIAa.
What is the protein family that this protein belongs to?
Belongs to the turripeptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPA_LEGPA
Sequence: MNYGLTHTPSLTTSECLVLGVFSDLALPDFATAIDNEQQGLIKKLCQRVPEPGNTVWQTDVEGHSLLIIQCGKKEEFSANSLQKRVGEITEALIKQRFSSATVCLPRLNQESAEWQLEQMIVQIDNLRYQLLDFKTKHAKSHKLESVIFHLPGATEKSLEMAKAIVTGVEFCRDLANMPANICTPTYLGEQAISLSKQFDQISCQVIGPEEIKEMGMGALLAVAQGSDQPPRLIDIHYHGNKNSAPVILVGKGITFDSGGLSIKPANAMDEMKYDMSGAASVLGVIKACALLKLPINLIGIIASAENLISGSAVKSGDIVTTMSGQTVEIINTDAEGRLVLADALTYAERYNPDFVIDIATLTGAIIVALGNIATGYMTRDEQLAKSIECAANESQDKVWRMPLDEAYQDALESPLADMINAGFDRSAGSITAACFLSRFTEKYRWAHLDIAGTAWISGKKRNATGRPVPLLIQLLRHVANSR
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.