PharMolix/UniProtQA huggingface dataset:
Protein: NDHI_ADICA
Sequence: MFLAIIKFQNYGQQVLEAANYIGQGFAVTLDHLNRLPITVQYPYEKKLPSERFRGRIHFEFDKCIACEVCVRVCPINLPVVDWIFLKDVKKKKLKNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSSYNRHELNFDQTALGRLPPPASEDVSIQLVLNSRNSFRR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RISB_BACC4
Sequence: MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEESDIDVAWVPGAFEIPLIAKKMASSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQMDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PROW_ECOLI
Sequence: MADQNNPWDTTPAADSAAQSADAWGTPTTAPTDGGGADWLTSTPAPNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLLGMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSRGNRRWYTTGPVGLLTRPFIK
What is the function of this protein?
Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake (PubMed:3305496, PubMed:7898450, PubMed:23249124).  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Glycine betaine/proline betaine transport system permease protein ProW.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMG_XYLFT
Sequence: MTDSFYRYDVIVIGAGHAGSEAALAAARTGAHTLLLTHNIETIGAMSCNPAIGGIGKGHLVKEIDALGGAMAHAADAAGIQWRTLNASKGPAVRATRCQADRSLYRAAIRQMIEGQARLNIFQAEVDDLLFEGDTVCGAITHTGLHFKAPAVVLTAGTFLAGKIHIGPTQYAAGRMGDPPATMLAARLRERLLTVARLKTGTPPRIDGRTLNYTAMQEQPGDAPRPTMSFIGNSASHPPQVSCWITQTTERTHEIIRAALHRSPLYSGQIEGTGPRYCPSIEDKVVRFAEKNSHQIFVEPEGLNVIDIYPNGISTSLPFDVQLELVRSIRGFEQAHITRPGYAIEYDFFDPRGLKASLETKAIAGLFFAGQINGTTGYEEAAAQGLLAGLNAARHVRGLSSWTPRRDQAYLGVLVDDLITHGTNEPYRMFTSRAEYRLQLREDNADARLTAIGRDLGLVDDARWAHFNAKQEAVARECGRLSALWATPGNALGREVKETLGVTLSRETNIIDLMKRPELDYAALMRVPSLGPGVDDAQVAEQVEISVKYAGYLNRQSEEITRQQRHEATAIPLEFDYAAVRGLSTEVLQKLQHIQPQTVGQAQRIPGMTPAAISLLLVHLERMRRNRVA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_CHLCH
Sequence: MKYDFTSIEKKWQTRWQAEATFATGTDHSKPKYYVLDMFPYPSGSGLHVGHLEGYTASDIIARYKRSSGYNVLHPMGWDAFGLPAEQFAIKTGTHPRITTEANVKNFKGTLQAMGFSYDWEREINTTDSGYFKWTQWIFLQLYDRGLAYMSEVDVNWCEELKTVLANEEVDEKLADGYTVVRRPLRQWVLKITAYAERLLADLEELDWPENVKQMQRNWIGRSEGVEIDFELRCHRTTLKAYTTRPDTLFGATYLVIAPEHPMAEKLATAPQLLVVKEYITKAKLKSDLERTGLQKEKSGVFTGSYAINPATGQPLPIWISDFVLISYGTGAIMSVPAHDSRDWAFAKQYNLPIIEVIKSPHDVQEAVFEEKNSTCVNSANDEISLNGLDFATAFERMATWLESKKVGKRKVNYKLRDWIFSRQRYWGEPIPIKHYEDGTIRPETNLPLELPAVEAYHPTSTGESPLANITEWLIGNDEHGAFRRETNTMPQWAGSCWYYLRFIDPHNHAQVVDGNNERYWMNVDLYIGGAEHAVLHLLYSRFWHKVLYDLGVVSTKEPFQKLFNQGMILGEDNEKMSKSRGNVIPADHVLQRYGADAVRLYEMFLGPLEQVKPWNTNGIEGISRFLGKVWRFVYPEHSEAATQPSNEPLPDELLRRMHKTIKKVGDDTSSLKFNTAIAEMMVFVNELTKTGCNNREAIETLLKLLAPYAPHMTEELWEALGHTNSISHEPFPTFNPALVEENMAIIAVQVNGKLRGTFTVPAKSPKEMLLEEARKVESVAKFLEGKTIVKEIVVPDKLVNFAVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEF_SIVGB
Sequence: MGSSQSKKRSEAWVRYSSALRQLVGGPVTPDGYKQIESSQGAEKQSLLRGRAYGTYSEGLDKVQNDPLTKDEKLDLTQQDPEEEEEVGFPVCRQVSLRVPSYKDLIDFSHFIKEKGGLGGIYYSRRREEILDLYAENEWGFEPGWQQYTTGPGTRYPKTFGFLFKLEPVSRAIGDEYAANNHLLHSSQLCPQEDPEGETLMWSGTLILPMTLQH
What is the function of this protein?
Interferes with TCR signaling from the cell membrane.  Interacts with CD247/TCRZ (TCR zeta chain) and exert potent down-regulation of cell surface TCR/CD3 complexes (By similarity).
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.
Protein: RNC_DELAS
Sequence: MPPLLNALQLRLQHQFAEPALLQRAVTHRSFSADNNERLEFLGDSVLNLAISSLLYQRLSSMPEGDLSRVRANLVKEGTLHQIALRLQLPDLLRLGEGESKSGGKQRPSILADAVEALIGAVYLDAGYAAGEKVVHHLFEGVDINPHMRAAEKDAKTALQEWLQGRRMKLPQYEVVATTGAAHRQTFEVACAIAELQLQARGTGASRRAAEQTAATAMLELLKARHA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SINFN
Sequence: MSRIGKKPVQVPAGVTASVDGQKVTAKGPKGELFFVANDEVSVKLENNAVVVQPLNESKDARAKWGMSRTMVENIFKGVKDGYERKLEINGVGYRASMQGKNLQLALGFSHDVVYQTPEGITIAVPKPTEIVVSGINKQQVGQVAAEIREYRGPEPYKGKGVKYAGERIVRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MED21_ASPCL
Sequence: MADILTQLQTCLDQLATQFYATIGYLSTYHDNSPATTPTNIPNAAPALAKIPKNSTAPPVPAGAPVPSQSSPPPPQTQRGASEAAADPNLPPAPDSPRTFASRQRELARDLIIKEQQIEYLISVLPGIDSSEAEQEKRIRELEAELRGVEEEREAKIRELRTLGRTLERVMGAVETGIYGDRAVLERDS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMH_ECOHS
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCCA_DICDI
Sequence: MFSLGKLVKKDAFFYRYITNVNKDLKIKPITKILIANRGEIACRVMRTAKSKGVKTVAVYSEADKNSLHVSMADESYLIGPAAAKESYLCGNKIIDVAKRSGAQAIHPGYGFLSENSDFADLCEREGIIFIGPPSDAIKAMGSKSASKDIMIKAGVPTIPGYHGEDQSMSVLKSEAAKIGYPVLIKAVMGGGGKGMRIVEREEDLEDGVESSKREATASFGDSRVLVEKYLVHPRHVEIQVFADRHGNCVHLFERDCSVQRRHQKIIEEAPAPHLSEELRKKMGDAAVAAAKAVGYVGAGTVEFILSADNSFFFMEMNTRLQVEHPITEMITKQDLVEWQLKVAESQTLPMEQEQLKIHGHSFEARIYAENPDSDFLPGTGKLAHLSTPTPSDTLRVETGVRQGDEVSVYYDPMIAKLVVWDQDREKALRYLRNALDEYHIIGLNTNISFLKRLSTHPSFMAGEVETGFIPIHRESLMAPQAPMSDDSLALAATSLLLKEITQQKSKEDPNSPWSSLGGFRINHNLKKQVKFNQKDNKVVVNVEFIGGGGAAANGKHNFKVTLDNGNVVEVLDAKLNQNNETISAHVNGRFYNNIKSVIVKDTLTIFNEGQQYQLDIPQDVKPKGADGVLGSLVSPMPGKITKVMVNVGDMVKKGQPILLMEAMKMEHTIRSPIDGKVESLPYNVNEIVEDKKTLAVIV
What is the function of this protein?
Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
What are the official names of this protein?
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ARGD_LEPIC
Sequence: MNDADIHKELFQHTKELADHYLLNTYARYDVAFRYGVNELLFDFDNKQYIDFHCGVAVTNLGHADPDIIEVVRSQADKLFHTSNLFYSEEASKLAELLILNSFPGKVFLTNSGTEAIEGAFKLARKYAYSKSIVDPIILSLEKSFHGRSVSGMSLTGQDKIRKGYGELLKGIEFIEPNNDEALVAAFERYQGRIVALIEEPILGESGIIPLSRNFLTLSRELTEENEALLIFDEIQTGMGRTGTLFAFETMGFSPDAMTLAKGLGSGFPIGALIVGEKYQDLFTQGSHGSTFGGNHLAAAVAYETIRIIQTREILNNVNICSDIAFTRLREMQEKYPVISEVRGKGLHIGLELKVPSKPIAEACLSAGLVVNATADNVVRIMPPLTISTDFLNQGLDILESVLKQN
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_STRA1
Sequence: MPKKTDTPDYKPSIYSLTRDELIAWAIEHGEKKFRASQIWDWLYKKRVQSFDEMTNISKDFIALLNENFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLNNGEITAQIMLVQKYFDERGQGERVSHIVVMGIGEPFDNYTNVLKFLRTVNDDNGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVSLHAPNNELRSSIMRINRSFPLEKLFAAIEYYIETTNRRVTFEYIMLNGVNDTPENAQELADLTKKIRKLSYVNLIPYNPVSEHDQYSRSPKERVEAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSNTMKRDRQKAKVGQ
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLD2_EMENI
Sequence: MATVTVSEISNQAAILRAELKEWERGFAAANGGKKAERGDIKKVPEIAAKYKEYSRLKSQESASSSKNDKSHSKPTDTQERSKKRKHSSPNGPEQSQSHCQTTSTPRKSAAGIFQTPSKLKTTHPADVDPYDSPSVLRRLFSPSTHMQTSSPLKTAIGPTPQRDGKALGLFDLLSESGGSTATPTAARMASLKGIAAQTPSKKRKMDTIREEDEEEEDSPRVERTPASSGKKYMLSALFATPTAWKYSSIVDDGTSRGVIGNNDVTKQSPQATRNIDHANANLETPSFLRRSTSGLTGPDPTDMSPLPVRKPQQFVGKGLSQLVQGLRDMEEERLEDEWDVLREIEIEQTGTGVDVPNSQAADPNSTGRTFKKKGQKRTTRLVKMRPVVQAKPTTTRSQPQSLSQSEPRFEHNLVSAGGSGDVDELGIDDNDLVAVAETQADGPPSGRVGIPAAFIDDDLDSLRSISEAEQDSDSDPDYDADSKPLGRSKSFSEKMKEAIGATGQGSDTKQAQERQKVKAKEKKEKENIDTNAKKPSTRKINPQAHANYRSLKIRNRGGGRNFGRFRRR
What is the function of this protein?
Has a role in the initiation of DNA replication.  Required at S-phase checkpoint (By similarity).
What are the official names of this protein?
DNA replication regulator sld2.
What is the protein family that this protein belongs to?
Belongs to the SLD2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYT17_HUMAN
Sequence: MAYIQLEPLNEGFLSRISGLLLCRWTCRHCCQKCYESSCCQSSEDEVEILGPFPAQTPPWLMASRSSDKDGDSVHTASEVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT
What is the function of this protein?
Plays a role in dendrite formation by melanocytes (PubMed:23999003).
What are the official names of this protein?
Synaptotagmin-17, Protein B/K, Synaptotagmin XVII, SytXVII.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: TNPA_BPMU
Sequence: MELWVSPKECANLPGLPKTSAGVIYVAKKQGWQNRTRAGVKGGKAIEYNANSLPVEAKAALLLRQGEIETSLGYFEIARPTLEAHDYDREALWSKWDNASDSQRRLAEKWLPAVQAADEMLNQGISTKTAFATVAGHYQVSASTLRDKYYQVQKFAKPDWAAALVDGRGASRRNVHKSEFDEDAWQFLIADYLRPEKPAFRKCYERLELAAREHGWSIPSRATAFRRIQQLDEAMVVACREGEHALMHLIPAQQRTVEHLDAMQWINGDGYLHNVFVRWFNGDVIRPKTWFWQDVKTRKILGWRCDVSENIDSIRLSFMDVVTRYGIPEDFHITIDNTRGAANKWLTGGAPNRYRFKVKEDDPKGLFLLMGAKMHWTSVVAGKGWGQAKPVERAFGVGGLEEYVDKHPALAGAYTGPNPQAKPDNYGDRAVDAELFLKTLAEGVAMFNARTGRETEMCGGKLSFDDVFEREYARTIVRKPTEEQKRMLLLPAEAVNVSRKGEFTLKVGGSLKGAKNVYYNMALMNAGVKKVVVRFDPQQLHSTVYCYTLDGRFICEAECLAPVAFNDAAAGREYRRRQKQLKSATKAAIKAQKQMDALEVAELLPQIAEPAAPESRIVGIFRPSGNTERVKNQERDDEYETERDEYLNHSLDILEQNRRKKAI
What is the function of this protein?
Promotes replication and thereby lytic development by competing with repressor c (Repc) for binding to the internal activation sequence (IAS) in the enhancer/operator region.  The outcome of this competition determines if the virus enters latency or starts replication.
What are the official names of this protein?
DDE-recombinase A, DDE-transposase A, Gene product 03, gp03, Gene product A, gpA, MuA.
What is the protein family that this protein belongs to?
Belongs to the mulikevirus repressor c protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RL7_BORAP
Sequence: MALNKEDILTWLEGAKTMEVVELVTAIEEKFGVTAAVATSVGGAASTGSTDSEEQTEFDVILMSFGDSKINVIKEVRSITGLGLGEAKALVESAPKAIKEGLSKSDAEELKKKLEAVGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y6882_SACEN
Sequence: MADPSFDVVSKIDRQEVDNALNQAAKELANRFDFRGTGTRIQWSGEEAITLESETEERCKAAIDVFKEKLIKRGISLKAFDVGEPASSGRVYKVTGKLVQGIAQDVAKKISKKIRDEGPKGVQAQIQGDQLRVSGKKKDDLQTVIQLLKSSDFDVALQFENYR
What are the official names of this protein?
UPF0234 protein SACE_6882.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: KGUA_MAGSA
Sequence: MTDTLPTVSRRGLMLVMSSPSGAGKTTISRALLERDPAIGMSVSATTRAPRPGEVDGKDYHFVTVEKFHEMVEKREFLEHARVFDNFYGTPRGPVDEILRSGRDVLFDIDWQGTQQMAQNARADLVSVFVLPPSVEELERRLRGRAQDSDEVVRKRMAKAGDEMSHWPEYDYIVVNIDLDKSIAAVQAILAAERLKRERQVGLPDFVTQLRGGE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQP5_HUMAN
Sequence: MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYEPDEDWEEQREERKKTMELTTR
What is the function of this protein?
Forms a water-specific channel (PubMed:8621489, PubMed:18768791).  Plays an important role in fluid secretion in salivary glands (By similarity).  Required for TRPV4 activation by hypotonicity.  Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723).  Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity).
What are the official names of this protein?
Aquaporin-5, AQP-5.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane.
Protein: TYSY_CORJK
Sequence: MAPQQQPSSIPTPYEDLLREILETGTPKGDRTGTGTTSLFGRQIRYDLSAGFPLITTKSVHVKSVVGELLWFLRGDSNVRWLQENGIRIWNEWADENGDLGPVYGVQWRSWPTPNGQHIDQIAGALETLQTNPDSRRNIVSAWNVSELDNMALPPCHLLFQLYVANGKLSCQLYQRSADMFLGVPFNIASYSLLTHMFAQQAGLEVGEFIWTGGDCHIYDNHVEQVKLQLSRDARPYPQLKLNKAADMFSYDFSDIEFTGYDPHPVIKAKVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XDH2_HALVD
Sequence: MMFGILGTAGIGVKSVIPAVQASEHEAAAIASRDEARASAVADELGIPTAYGSYEALLADDSLDAVYIPLPNGLHADWVRAAADRGLHVLCEKPLTASADETAAVFDYCEDAGVTLMEAFMYRFHPLTERAAELVASELGAVVSVTSNFSFRLPDGADDIRIDPDLAGGSVMDVGCYAVSAARLFLGTPDRVYATTTDTRDCGVDTRMSGVLEYDSGATARVESSFDTPETQYYRVQTTDGRLEANPAFNVDPTAAAELTYATDGRVVTETFDPTDSYRREVEAFARAVETGETPRVDREESVSVMRTIDAIYESAETGAAVELD
What is the function of this protein?
NADP-dependent D-xylose dehydrogenase involved in the degradation of D-xylose, a major component of hemicelluloses such as xylan.  Even if it shows D-xylose dehydrogenase activity, it is not essential for D-xylose degradation.
What are the official names of this protein?
D-xylose 1-dehydrogenase (NADP(+)) 2, XDH 2.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
What are the subcellular locations of this protein?
Secreted.
Protein: MED19_CAEEL
Sequence: MNEPSACSGPPVKSKSSKNEPFYTLKALLPPYSEIQGNHDLLMSYELGPVEGGFSGSRRVKEKISSFLPHIIGEFHLDATKEASSLRALIEKPPIHKEISNLTSSSMQGFKLSAGPVDERYRHLFERRKEEPNLAYSEKLNLIRVRQQYDAYGFDDDETEKGFPKKHKKKKKDKKRKKEKEELGDAEKRKRAADEPMEF
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA2A7_GLOHA
Sequence: SLLQFETLIMKVAKKSGMVWYSNYGCYCGWGGQGRPQDATDRCCFVHDCCYGKVTGCDPKMDVYSFSEENGDIVCGGDDPCKKEICECDRAAAICFRDNLNTYNDKKYWAFGAKNCPQEESEPC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 A, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.