PharMolix/UniProtQA huggingface dataset:
Protein: GGGPS_THEVO
Sequence: MTILKQMMRKLKNEKIHMTLIDPAAKSPDESAKIAKEAEMAGTDFIMVGGSTDIDERLMDQTVSAIKENTNLKVILFPGSSNMISRHADAIFFMSLLNSSDREFIVGHQVKASKFLSLLGIEKIPMAYLVFSPGMTVGRVGKANLIDSFDRETALSYSLAAQYMGFKLIYFEAGSGAPRPVSEDTISYVKSKINIPLIVGGGIRDPETAMRIALAGADMIVTGSIAEKSNNVYSVLRNIIGKIKSIEIKNSV
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR27_HUMAN
Sequence: MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDDEDAPCALEQRPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPRTTQATHPCDLKGIGL
What is the function of this protein?
Orphan receptor.  Possible candidate for amine-like G-protein coupled receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HUTI_STRSV
Sequence: MTADLLLTHFNQVFCPKDLGHPLFGEEMKEAQVLEDGYIAVKDGKILAVGSGEPDASLVGPDTKIQSYEGKIATPGLIDCHTHLVYGGSREHEFAKKLAGVPYLEILAQGGGILSTVRATREASFDTLYDKSRRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVGALDRDHEIDLVSTFMAAHAVPPEYKGRSQEYLELIVEEMLPRVKAENLAEFCDIFCEKGVFTADESRYLLSKAKEMGFKLRIHADEIESIGGVDVAAELGATSAEHLMVATDEGIRKMAEAKVIGNLLPATTFSLMEDTYAPARKMLEAGMAITLTTDSNPGSCPTANLQFVMQLGCFMMRLTPVEVLNAVTINAAYSVNRQDKIGSFDTGKQADITILDAKNIDYPLYFFATNLTHQVYKAGKLVVDQGRIV
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_FRATW
Sequence: MTQIMTPKTIVHELERHIIGQNDAKKAVAIALRNRWRRMQLDNEMRQEVTPKNILMIGPTGVGKTEIARRLAKLADAPFIKVEATKFTEVGYVGKDVESIIRDLVETAVKMKREEAKEKVTEKAARLAEDRILDVLIPPARTSESKVGFANEPAEDAASKKEKENKTREIFRKKIQNGELDDKEIEIEVAVAPKTIGVMGPPGMEDMTSQLQDLFSSLSTDKKKNKKMRIKDAIKLAQDEEAAKLVNEEDIKARALEAVEQNGIVFLDEIDKVCRKSSNSGADVSREGVQRDLLPLVEGSTVSTKYGVIKTDHILFIASGAFHVAKPSDLIPELQGRLPIRVELKSLEIEDFVRILREPDCSILKQYIALMKTEGIDLSFEEDAIRKIAEIAYKVNEEVENIGARRLHTVMERLLEKISFDAPELVEKNINITTDYVNEKLGNLVKNKDLSQYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN8_DROME
Sequence: MHLNKYSEVVERLENEEFEQVELGAEVYQQLLAIYLYQNKLADAKLLWMRVPANLRDDKELIQLNLLNIALQNNNYADFFKHIKYEWSERVKSPVEDLLNKQREELFKLMGSAYMSIYQHNLLELSLMSEDELKHACAALNWTEELDGDRVILKPKVQEAPPARGNDDQLLKLTEFVTFLEN
What is the function of this protein?
Probable component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting.  It also promotes Ubl-dependent degradation of cyclin E (CycE) during early oogenesis.
What are the official names of this protein?
COP9 signalosome complex subunit 8, Dch8, Signalosome subunit 8.
What is the protein family that this protein belongs to?
Belongs to the CSN8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HDA_SALPB
Sequence: MSSWVEVSLNTPAQLSLPLYLPDDETFASFWPGDNASLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECVAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDHASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: TGFA1_DANRE
Sequence: MSVKAFDLVPAVEREQVMGEKVRINIECIECCGQHLYLGTNDCFIHHFLLEEHTTAKGKLAFNAQKLLHKYLGLKKPVVELKAASALERLIVLCDSAITVVDMVTLEPVPTGGAKLKGVTAFCINENPVTGDAFCVEMAVVLARRRAVQICTVHEDRVQMLKEVTTPEQPCALSLDGYNICLALSTQYMILNYSTGASQDLFPYDCEERKPIVKRIGREEFLLAAPGGLGMFANAEGISQRAPVSWSENVIAAAVCFPYVVALDEGFVTVHSMLDQQLKQTLSFRDGQLLQDFEGKVVVASSKAVYMLVPLPLERQIQDLLASHRVEEALTLTEAAQRNIPKEKYQILHRRILQQAGFIQFGQLQFLEAKEHFRKGQLDVRELISLYPLLLPASSSFTRCHPPLHEFADLNHLTQGDQEKVQRFKRFLISYLHEVRSSDIANGFHEDVDTALLKLYAETSHESLLDLLASENACLLADSAPWLEKHHKYYALGLLYHYNGQDAAALQMWVKIVNGDLQDSTRPDLFEYVVDFLSFCSNLDLVWRHADWALQKDQKIGVQIFTKRPTSEERRGQLNADDVITYLQKHSQALLLYLEHLVLEKKLQKEKYHTHLAVLYAEKVLGLISRPSTSEEQLSAARQKLQRLLKESNLYRVQLLLGKIQDSELLLLERATLHGKLEEHDKALHVLVHQLKDSSAAEEYCSWASASQDSSYRQNLFHQLLSVYLDPDVPGGAQTVAAVDLLNRHAEVFDAVRVLKLLPEDWSLPLLRPFLCGAMRATVHARCTSQVALGLARAQNLQLLHDRLKYRGGPVLVSEKKGCQLCHNTFSEPDCACLPGGTPVHINCVAKKALDLPHENAHHSNHT
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway.  Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.  The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (By similarity).
What are the official names of this protein?
Transforming growth factor-beta receptor-associated protein 1 homolog, TGF-beta receptor-associated protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome.
Protein: LRC34_MOUSE
Sequence: MEKLQAQYCYLCSENIRKTNPFILNILQKLDEEIEKRPKEKFTVNIAGNNRLDSGQRITGEDFWLLSKTLRNQPCISGVDVRYNLIGDVGAFYAAKLLQKQPSITYLNLMFNDIGPEGGELIAKALHKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQCVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHIGHMLKENHVLVELHMCKHGMKNYGLQQLCNALYLNSSLRYLDVSCNKITRDGMVFLADVLKSNTTLEVLDLSFNRIETAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLVLSNIYIWGNKFDEDTCVAYSDLIKSGRLKPDNTDVEPYMVDEHIYLSEVSNGLKRHYYWAPTYGETYMPSSSAGFALVPVGEHL
What is the function of this protein?
Highly expressed in stem cells where it may be involved in regulation of pluripotency.  In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4.  Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4.  Promotes stem cell proliferation in vitro.
What are the official names of this protein?
Leucine-rich repeat-containing protein 34.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Note=As stem cells differentiate, translocates from the nucleolus to the nucleus and then to the cytoplasm. Colocalizes with NPM1 and NCL in the nucleolus.
Protein: MLTB_ECOLI
Sequence: MFKRRYVTLLPLFVLLAACSSKPKPTETDTTTGTPSGGFLLEPQHNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTTSVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIGVETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFAGAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMANGQAPGLPNGFKTKYSISQLAAAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYTITRYNHSTHYAMAVWQLGQAVALARVQ
What is the function of this protein?
Murein-degrading enzyme.  Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase B, 35 kDa soluble lytic transglycosylase, Murein hydrolase B, Slt35.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: SECY_STAAC
Sequence: MIQTLVNFFRTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPAAFDNPQGSQGATELLNTFGGGALKRFSIFAMGIVPYITASIVMQLLQMDIVPKFSEWAKQGEVGRRKLNNVTRYLAISLAFIQSIGMAFQFNNYLKGALIINQSIMSYLLIALVLTAGTAFLIWLGDQITQFGVGNGISIIIFAGILSTLPASLIQFGQTAFVGQEDTSLAWLKVLGLLVSLILLTVGAIYVLEAVRKIPIQYAKKQTAQRLGSQATYLPLKVNSAGVIPVIFAMAFFLLPRTLTLFYPDKEWAQNIANAANPSSNVGMVVYIVLIILFTYFYAFVQVNPEKMADNLKKQGSYVPGIRPGEQTKKYITKVLYRLTFVGSIFLAVISILPILATKFMGLPQSIQIGGTSLLIVIGVAIETMKSLEAQVSQKEYKGFGGR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URM1_MOUSE
Sequence: MAAPLCVKVEFGGGAELLFDGVKKHQVALPGQEEPWDIRNLLVWIKKNLLKERPELFIQGDSVRPGILVLINDADWELLGELDYQLQDQDSILFISTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN_HHV7J
Sequence: MAIDYAQISCNLASIIEEDSVFLFLIDKLNNLDISRRKISFNFIRLCYTYYILIKFNSRFKDTFLARSFIDYMHQNISDFIDENVELSDLYSNIYVRLQDASPKVVKNLFKILERETRGQSTNPLWHAMRKNCITATKIYDIYISKSFSGIQEHSYLGDAVLYGIKHERIIEHLLKTFFVKKPWISKTLGLLLDPSSGVFGASIDSYYGISFNDNNLIEVGDKVVIFELKFRYKYLREKNDLFVSELLQNPSEIALAKFILSHPIPAIEYRENGKMPSAREYLITNNPLYDSGKKRRACLTPKNLTFDITRLIPMNEKNVSTAIIFDVVKDCILNTLVAYQKAIFTIDAFINPRHRYYFQSILQQYVMTQFYIQDHDNPENIEKENLPSVYIVSAIFRKREDDEKNCRLLIEDTEYLEEEIPLILLITPITIDAEFTSRVIKDICCIWENKIAQQTNLKIWAQSAVRQYMAASSARPKTP
What is the function of this protein?
Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules.  Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate.  Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides.  Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.
What are the official names of this protein?
Alkaline nuclease.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae alkaline nuclease family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: UPP_STRPD
Sequence: MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEVSRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCLVAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SLU7_DROME
Sequence: MSSGPMRTPVSQIILSKHDQDAEEEPKKKSREDWRKAKELEEARKAGTAPAAVDEEGRDINPHIPQYISNAPWYYGSAGPTLKHQRPQHEDEQGQLDKRAPKGLNTARIITKFRKGACENCGAVTHKRKDCLERPRKVQAKYAESIVVHDEHLVNEAAVNYDEKRDRWSSYDPANHREIIEEYEKVEEAKRQLKAEKLKNDPDAEISDEEGNEDKYVDEVDMPGTKVDSKQRITVRNLRIREDTAKYLRNLDPNSAYYDPKTRSMRDNPNPAVPEEEAEFAGENFVRFSGDTTAQATAQLFAWEAHGKGVDVHLLAEPTKLELLQKEYEQKKEQFKSSTKTHIVEKYGGEEHLQVPPKSLLLAQTEEYIEYSRSGKVIKGVEKPKARSIYEEDVYINNHTTVWGSFWNAGRWGYKCCKSFIKNSYCVGMQEPEGYSEHHSTSSTAAATTEPAAQSQFKVPEVPPERPTSEVDSASSSEPSSSEEEEVKPEKKKTKKKSKKREKKKKAKEQRKQKGKNKETKDKDKTKEKDIPEELDDRKRAYNSMYDVKAPTEDEIEEWKKKRPRAEDPMLQFM
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron.  Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region.  May be involved in the activation of proximal AG.  Probably also involved in alternative splicing regulation.
What are the official names of this protein?
Pre-mRNA-splicing factor Slu7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Predominantly nuclear.
Protein: RS15_PSEPW
Sequence: MALSVEEKAQIVTDFQQAAGDTGSPEVQVALLTANINKLQGHFKANGKDHHSRRGLIRMVNQRRKLLDYLKGKDTTRYSALIGRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ELOV2_RAT
Sequence: MFGPRDSRVRGWFLLDSYLPTFTLTIVYLLSIWLGNKYMKNRPALSLRGILTLYNLGITLLSAYMLVELVLSSWEGGYNLQCQNLDSAGEGDIRVAKVLWWYYFSKLVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHRYLWWKKYLTQAQLVQFVLTITHTLSAVVKPCGFPFGCLIFQSSYMMTLVILFLNFYIQTYRKKPMKKEMPEGAAGKEVKNGFPKAHSIAANGVTDKKVQ
What is the function of this protein?
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle.  Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA.  May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
What are the official names of this protein?
Elongation of very long chain fatty acids protein 2, 3-keto acyl-CoA synthase Elovl2, ELOVL fatty acid elongase 2, ELOVL FA elongase 2, Very long chain 3-ketoacyl-CoA synthase 2, Very long chain 3-oxoacyl-CoA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the ELO family. ELOVL2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HUTI_DANRE
Sequence: MSANSFKLLVKNATQLVLVCRNGEKYLTRDEMQALAVLENASVLIGHDGLIKAVGPADVIETQFEGAKFDNVLDASGMCVLPGLVDAHTHPVWAGDRVHEFAMKLAGATYMEVHEAGGGIHFTVAHTRSASEQHLLAALKSRLERMMRAGTTLVECKSGYGLELDIEVKMLRVINSARKSLPIGISATYCGAHAVPKGKTMEEATKDIVAVQLPKIKHLSASGDLQVDNIDVFCEKGVFDLTSTRCILQAGKDMGLNINFHGDELHPMNSAHLGAELGALAISHLEEVTDDGIVAMAKSKTSAVLLPTTAYILRLTPPRARDMLDAGVIVALGSDFNPNAYCFSMPMVMHLACVMMKMSMPEALAASTINAAYALNRSQTHGSLEVGKQGDLVIINAPRWEHLVYQFGGHQELIRYVIIKGDFVYENDKVLNL
What are the official names of this protein?
Probable imidazolonepropionase, Amidohydrolase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
Protein: DHAQ_LACLA
Sequence: MKFYNSTNEIPEEMLKGIDLTYPQLTYLPETGILYDNTYNEKTVPIISGGGSGHEPAHVGYVGSGMLAAAVTGPLFIPPKSKNILKAIRQVNSGKGVFVIIKNFEADLKEFNEAIKEARTEGIDVRYIVSHDDISVNAYNFHKRHRGVAGTILLHKILGAFAKEGGSIDEIEQLALSLSPEIYTLGVALAPVHFPHQKTSFVLAEDEVSFGIGIHGEPGYRVEKFEGSERIAIELVNKLKAEINWQKKANKNYILLVNGLGSTTLMELYSFQYDVMRLLELEGLSVKFCKVGNLMTSCDMSGISLTLCSVKDPKWLDYLNVPTGAFAW
What is the function of this protein?
Coactivator for the transcription factor DhaS.  The heterotetramer formed by DhaQ and DhaS functions as transcriptional regulator.  Activated by covalent binding of dihydroxyacetone to DhaQ.  The complex activates the dhaKLM operon.
What are the official names of this protein?
DhaKLM operon coactivator DhaQ, DhaS coactivator DhaQ.
Protein: IXTPA_NOCFA
Sequence: MTMARVLVASRNAKKLAELRRILDDAGVAGVQIVGLDDVPPYDEAPETGATFEENALAKARDGAAATGLPCVADDSGLAVDALNGMPGVLSARWSGTHGDDAANNALLLAQLRDVPDERRGARFVSACALVVPGGTETVVRGEWPGTIGRKPMGEGGFGYDPLFVPDGGDVTAAQLTPAAKDAASHRGRALRHLLPALAALADRTE
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: FABH_BRUC2
Sequence: MIRSVVRGIGSALPKRVMKNTDFEGIVETSDEWIVQRTGIRERHIAGEGETTVSLGAAAARAAIENAGLQPSDIDLVLLATSTPNNTFPASAVAIQRELGITRGFAFDLQAVCSGFIYAITTADLYIRGGMARRVLVIGAETFSHILDWTDRTTCVLFGDGAGAIVLEAAEGHGLTSDRGILAANLRSDGNHKEKLYVDGGPSTTQTVGHLRMEGREVFKHAVGMITDVIEASFEATGLTAEDIDWFVPHQANKRIIDASAKKLHIAEEKVVITVDRHGNTSAASVPLALATAVADGRIKKGDLVLLEAMGGGFTWGAVLVRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPR_BACAC
Sequence: MKSGEKDYSVKEAMIFSQRIAQLSKALWKCVEKDWQMWIKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDDKRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIELIAILRNIYGQDFIDIFEKSLEDIEENFTESDQKLVKK
What is the function of this protein?
Negative regulator of protease production and sporulation.
What are the official names of this protein?
HTH-type transcriptional regulator Hpr, Protease production regulatory protein Hpr.
Protein: RS7_METLZ
Sequence: MTEEAATSKILLFNKWDMSEVVVKDAGMVRYVTITSTEVPSSCGRLTQQQFTKSEMAIVERLINRLMQQEYNTGKKMMCTKMVMDAFDVINKKTKQNPLQVLVDAVANAGPREETVRLKYGGINVPKSVDSAPIRRVNTALRYIALATWKGSHKTKKPAYLVLADELIMAAKGDAKCFSVGKKEEVERIAKSAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MNMA1_CLOBL
Sequence: MKKKVLVGMSGGVDSSVAAYLLKEQGYEVIGVTMQIWQDDEEFIEKEGGCCSLSAVADARRVANKIGIPFYVMNFKDAFKRNVIDYFVDEYMEGRTPNPCIACNKFIKFSSFLDKAMAMGIDYVATGHYAIIEKHNDRYIIKKSEDDKKDQTYALYNLTQFQLERTLMPCGQYKKSKIREIAKEIGLRVHNKKDSEEICFIPDNDHGRYIKNRFPNKVREGNFVDKQGSILGTHKGIVYYTIGQRKGLGIAFGKPMYVVDINPFRNEVVLGDLEDLLNTELIAKDTNYIPFDTLKEPMEVEAKIRYSQTPSKAIITPIEDGRVRVNFHEKQRAITKGQSVVFYKDDLLIGGGIIEK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 1.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CML1_ORYSI
Sequence: MADQLSEEQIVEFREAFSLFDKDGDGSITTKELGTVMRSLGQNPTEAELQDMISEVDADSNGNIEFKEFLGLMARKLRDKDSEEELKEAFRVFDKDQNGFISAAELRHVMANIGERLTDEEVGEMISEADVDGDGQINYEEFVKCMMAKKRRKRIEEKREHDGGSRTKSAGPSAAPASKRGQKCVIL
What is the function of this protein?
Calcium-binding protein that binds and activates CAMK1, a calcium/calmodulin-dependent kinase.
What are the official names of this protein?
Calmodulin-like protein 1, OsCaM61.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.