PharMolix/UniProtQA huggingface dataset:
Protein: CCA_LISW6
Sequence: MNDVFLKALPVLQKLTTAGFEAYFVGGSVRDYLLCRTISDVDIATSAFPEEVKEIFPSTYDTGIAHGTVTVRENKECYEVTTFRTEGTYEDFRRPSEVTFIRSLKEDLQRRDFTMNAIAMDEHFELHDPFFGQLAIQNKEIKAVGKASERFQEDALRMMRAVRFLSQLDFHLDKETENALQKNIALLQHTSVERITVEWVKLMKGPAVKRAINVLLKVEMETYLPGLKGEKSALIPFASWEWDKRTTENVIWLGLAVAVKKANVTSFLKAWKLPNKTIQLVNQAYQYALNGKEYWQKEELYYAGKEVFSLVNEINVIRGQENKQNELDQLYETLPIHSKKDLAITGGDLLEWADKSAGPWIKDTLDKVESAVLSQAINNDKKHIKRWLGYHEE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: EFG2_DESPS
Sequence: MVAQINLKDVRNIGIMAHIDAGKTTTTERILYYTGRSHKIGEVHDGNAVMDWMEQEQERGITITSAATTCIWKGKKINIIDTPGHVDFTVEVERSLRVLDGVVAVFCAVGGVEPQSETVWRQANKYFIPRVAFINKMDRVGADFDHCLAMIEKRLRANPVAVQIPVGSEAEFAGVIDLIEGEMYAFDDATLGQEVERREVPTEYKERFTAARISLLEKLADFDEELMEKFLDDELISSATIYKALRKATLALELVPVFCGSAFKNKGVQPLLDGVVNYLPSPLDVKPVEGVDKDGVEVSRKADPSEKFAGLVFKLMSDSFVENLAFIRVYSGTLKQGDKVFNPIKGKQEKIGKLLRLHANKREEVKEIVAGDIGAVVGLKFTTTGDTLCEKEAQIILESMEFPDPVIGVAIEPSSKADEKKLTESLAKIALEDPSFVVSQNEDTGQTIISGMGELHLEIIVYRLLNEFKVAARVGTPQVSYKESIQRSHSAEGLFEQPTGSSNQFAKVVLEIEPLERGAGIEFVCEVDEKQIPAEFLGAVERGVVDSLDSGPLVGYPVTDVRVRLVGGAYHEEDSTEMAFGVSASIAVRKAASEADSVLLEPIMSLEVITPDEYLGDAIGDLNKKRAKVVGVEVEGDLQKLLAHVPLSEMFGYSTSLRSATQGRANFTMQFLAYDVVPANKAETIIKKIRGI
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_METNO
Sequence: MNVLGIETTCDETAAAIVAAAEDGRGVIRANEVLSQIAEHAAYGGVVPEIAARAHVEVLDRLIARALHETGLVFDDLDGIAVAAGPGLIGGVLVGLVTAKTLALVTRKPLLAVNHLEAHALTARLTEGIGFPYLLLLASGGHTQLVAVKGVGEYLRLGTTIDDAIGEAFDKVAKLLGLAYPGGPEVERAAETGNPERFALPRPMLGRREPNFSLSGLKTALRLEAERIAPLTNQDVADLCASFQAAIVDVVVDRVRGALRAFGDVAGHPTALVAAGGVAANGALRRALTQLAGEAGLPLVAPPLPLCGDNGAMIAWAGLERLRLGLIDDITAPARPRWPFAEALPATAG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_HORSE
Sequence: MTNIRKSHPLIKIINHSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLFIHVGRGLYYGSYTFLETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVVVHLLFLHETGSNNPSGIPSDMDKIPFHPYYTIKDILGLLLLILLLLTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALIPTLHMSKQRSMMFRPLSQCVFWLLVADLLTLTWIGGQPVEHPYVIIGQLASILYFSLILIFMPLASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL29_RICTY
Sequence: MNDLKLLRSKLSTETIEELYKNLNLLKKELFNLRFQQALGELKNTSRFSLVKKSIARIKTELTKRSNSEEY
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: TGT_ACIBT
Sequence: MKFEKLGQSGRARRGRLTLEHGVVETPVFMPVGTYGTVKGMLPRDIEDIQAQIILGNTFHLYLRPGLEVIKQHGGLHDFIKWNKPILTDSGGFQVFSLGAMRKIKEEGVTFRSPIDGSKVFLSPEISMEIQHVLNSDIVMIFDECTPYPATHEEAQKSLQLSLRWAKRCKAHHHDELKNKNALFGIIQGGMYEDLRDESLNGLLEIGFDGYAIGGLSVGEPKEEMIKVLDYLPNKMPHDKPRYLMGVGKPEDIVEAVRRGVDMFDCVMPTRNARNGHYFVTDGLVRIRNSKYRHDQGPLDPHCDCYTCKNFTRAYLFHLEKCGEMLASMLGTIHNLRYYQRLTEGMRDALDNGTFDEFVQDFYARRGLEVPPCPVDE
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: HSLV_BRUAB
Sequence: MIEHNPTTIYGTTIVTVRKDGKVVIAGDGQVSLGNTVMKGNARKVRRIGKGNVIAGFAGTTADAFTLLERLEAKLEQYPDQLMRASVELAKDWRTDRYLRKLEAMMLVADSKVTLALTGTGDVLEPEQGVMAIGSGGNYALAAARALIETDKSAEEIARKAMNIAADICIYTNHNIIVESLDAQ
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP171_MOUSE
Sequence: MTNSSTFCPVYRDLEPFTYFFYLVFLIGIIGSCFATWAFIQKTTNHRCVSIYLINLLTADFLLTLALPVKIIVDLGVAPWKLRIFHCQVTACLIYINMYLSIIFLAFVSIDRCLQLIHSCKIYRIQEPGFAKMISAVVWLMVLLIMVPNMVIPIKDIKEKSNVGCMEFKKEFGRNWHLLTNFICVAIFLNFSVIILISNFLAIRQLYRNRDNTNYPSVKSALLHILLVTASYIICFVPYHAVRIPYTLSQTEVISDCSTRIALFKAKEATLLLAVSNLCFDPILYYHLSKAFRLKVTETFASPKKSKPLEERLRSENDV
What is the function of this protein?
G-protein coupled receptor for Big LEN, a 16-amino acid neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N) (PubMed:24043826, PubMed:28425495).  Acts through a G(i)-alpha-mediated pathway in response to Big LEN (PubMed:24043826).  Big LEN-GPR171 system plays an important role in regulating feeding and metabolism (PubMed:24043826).  Also plays a role in modulating fear and anxiety-like behaviors in the basolateral amygdala (PubMed:28425495).  Big LEN-GPR171 modulates the mu-type opioid receptor signaling and antinociception (PubMed:31308196).  Acts as a negative regulator T cell function (PubMed:34615877).
What are the official names of this protein?
G-protein coupled receptor 171.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalized with GPR83 in the paraventricular nucleus.
Protein: RIMM_STRGG
Sequence: MQLVVARIGRAHGIKGEVTVEVRTDEPELRLGPGAVLATEPAATGPLTVEAGRVHSGRLLLRFEGVRDRTGAEALRNTLLIAEVDPDELPEEEDEFYDHQLIDLDVVLADGTGIGRITEISHLPSQDLFIVERPDGSEVMIPFVEEIVTEIDLEEQRAVITPPPGLIDESEAVVASSRDEETGEAASGDEAEAPKGDA
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_STAAT
Sequence: MTNVLIEDLKWRGLIYQQTDEQGIEDLLNKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMIGDPSGKSEERVLQTEEQVDKNIEGISKQMHNIFEFGTDHGAVLVNNRDWLGQISLISFLRDYGKHVGVNYMLGKDSIQSRLEHGISYTEFTYTILQAIDFGHLNRELNCKIQVGGSDQWGNITSGIELMRRMYGQTDAYGLTIPLVTKSDGKKFGKSESGAVWLDAEKTSPYEFYQFWINQSDEDVIKFLKYFTFLGKEEIDRLEQSKNEAPHLREAQKTLAEEVTKFIHGEDALNDAIRISQALFSGDLKSLSAKELKDGFKDVPQVTLSNDTTNIVEVLIETGISPSKRQAREDVNNGAIYINGERQQDVNYALAPEDKIDGEFTIIRRGKKKYFMVNYQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3615_KLEP3
Sequence: MDHRLLEIIACPVCNGKLYYSQDKQELICKLDSLAFPLRDGIPVLLETEARALTVEESHS
What are the official names of this protein?
UPF0434 protein KPK_3615.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: DPO4_PSEPF
Sequence: MTQRKIIHVDCDCFYAAIEMRDDPSLAGKPLAVGGSADRRGVIATCNYEARAYGVRSAMSSGHALKLCPDLTIVKPRMDAYREASKEIHTIFSDYTDLIEPLSLDEAYLDVSDSAHFGGSATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWRKPNGLFVITPDQVEEFVSGLPVSKLHGVGKVTADKLGKLGINDCLQLREWDKLALVREFGSFGERLWSLARGIDERLVHNDSRRQSISVENTYDVDLPDLRSCLDKLPELLETLKTRMARIDSSYRPGKPFVKVKFHDFTQTTLEQAGAGRDLGSYQLMLTQAFNRGGKPVRLLGVGVRLEDLRGGFEQMELFER
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSS4B_PROMP
Sequence: MVCTQRVAGLGHMNLRILENNKGKKVVAVDPVGAREGNWVFTASGSAARFACPNPEVQTDLTIGGIIDYWESN
What is the function of this protein?
Probably forms vertices in the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) is sequestered.  Has been modeled to induce curvature upon insertion into an otherwise flat hexagonal layer of major carboxysome subunits (By similarity).  Has not been identified in purified carboxysomes; it is expected to be present in very low amounts (Probable).
What are the official names of this protein?
Carboxysome shell vertex protein CsoS4B.
What is the protein family that this protein belongs to?
Belongs to the CcmL/EutN family. CsoS4 subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=Probably forms vertices in the polyhedral carboxysome (By similarity). This bacterium makes alpha-type carboxysomes (PubMed:22155772).
Protein: FKBP3_RABIT
Sequence: MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQDHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGSENVTKVSEQVKNVKLNEDKPKETKSEETPDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLIFEVELVDID
What is the function of this protein?
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways.  PPIases accelerate the folding of proteins (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-25, FK506-binding protein 3, FKBP-3, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIA1_ORYSJ
Sequence: MAASVQPRQFGHLEPGSAPVRGAASSNGAKAYPPANGIPRRADSPVRGCGFPPLVSPPPRKPPSDGSDDEEEEQEDWRELYGSHLQLEVEPPVRDARDEGTADAWIERNPSLIRLTGKHPLNCEPPLARLMHHGFITPAALHYVRNHGAVPRGDWSTWTVDVTGLVKRPMRLTMDELVNGFPAVEIPVTLVCAGNRRKEQNMVQQTVGFNWGAAGVSTSVWRGARLRDVLRRCGIMPSKGGALNVCFEGAEDLPGGGGSKYGTSITRQWALDPSRDIMLAYMQNGEPLLPDHGFPVRAIIPGCIGGRMVKWVKRIIVTTAESDNYYHYKDNRVLPSHVDAELANADAWWYKPEYIINELNVNSVITTPGHDEILPINGITTQRGYTMKGYAYSGGGKRITRVEVTLDGGETWLVCVLDLPEKPTKYGKHWCWCFWSVEVEVLDLLGAKEIAVRAWDQSHNTQPEKLIWNLMGMMNNCWFKVKVNVCRPHKGEIGLVFEHPTQPGNQTGGWMARQKHLETAEAAAPGLKRSTSTPFMNTTDGKQFTMSEVRKHSSQDSAWIVVHGHVYDCTAFLKDHPGGADSILINAGTDCTEEFDAIHSDKAKALLDTYRIGELITTGAGYSSDNSVHGASNLSQLAPIREAIKAPAPVALSSPRDKVPCQLVDKKELSRDVRLFRFALPSSDQVLGLPVGKHIFVCASIEGKLCMRAYTPTSMVDEVGHFDLLIKVYFKNEHPKFPDGGLMTQYLDSLPVGAYIDVKGPLGHVEYTGRGEFVINGKPRNARRLAMIAGGSGITPMYQVIQSVLRDQPEDTTEMHLVYANRTEDDILLRDELDRWAAEYPDRLKVWYVIDQVKRPEEGWKYGVGFVTEEVLREHVPEGGDDTLALACGPPPMIKFAVSPNLEKMKYDMANSFIVF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADH] 1, NR1.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: FPG_SALAR
Sequence: MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRLSDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILSEAQPAEKHDHVDLVMSNGKILRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKRKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSKEECDLLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPVVATKHAQRATFYCRHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TSN2_ARATH
Sequence: MATGAATENQWLKGRVKAVTSGDCLVITALTHNRAGPPPEKTITLSSLMAPKMARRGGIDEPFAWESREFLRKLCIGKEVAFKVDYKVEAIAGREFGSVYLGNENLAKLVVQNGWAKVRRPGQQNQDKVSPYIAELEQLEEQAQQEGFGRWSKVPGAAEASIRNLPPSAVGDSGNFDAMGLLAASKGKPMEGIVEQVRDGSTIRVYLLPEFQFVQVFVAGLQAPSMGRRQSTQEAVVDPDVTATSNGDASAETRGPLTTAQRLAASAASSVEVSSDPFAMEAKYFTELRVLNRDVRIVLEGVDKFNNLIGSVYYSDGDTVKDLGLELVENGLAKYVEWSANMLDEEAKKKLKATELQCKKNRVKMWANYVPPASNSKAIHDQNFTGKVVEVVSGDCLVVADDSIPFGSPMAERRVCLSSIRSPKMGNPRREEKPAPYAREAKEFLRQKLIGMEVIVQMEYSRKISPGDGVTTSGAGDRVMDFGSVFLPSPTKGDTAVAAAATPGANIAELIISRGLGTVVRHRDFEERSNHYDALLAAEARAIAGKKNIHSAKDSPALHIADLTVASAKKAKDFLPSLQRINQISAVVEYVLSGHRFKLYIPKESCSIAFAFSGVRCPGRGEPYSEEAIALMRRKIMQRDVEIVVENVDRTGTFLGSMWEKNSKTNAGTYLLEAGLAKMQTGFGADRIPEAHILEMAERSAKNQKLKIWENYVEGEEVVNGSSKVETRQKETLKVVVTEVLGGGRFYVQTVGDQKVASIQNQLAALSLKDAPIIGSFNPKKGDIVLAQFSLDNSWNRAMIVNGPRGAVQSPEEEFEVFYIDYGNQEIVPYSAIRPVDPSVSSAPGLAQLCRLAYIKVPGKEEDFGRDAGEYLHTVTLESGKEFRAVVEERDTSGGKVKGQGTGTELVVTLIAVDDEISVNAAMLQEGIARMEKRRRWEPKDKQAALDALEKFQDEARKSRTGIWEYGDIQSDDEDNVPVRKPGRG
What is the function of this protein?
Cytoprotective ribonuclease (RNase) required for resistance to abiotic stresses, acting as a positive regulator of mRNA decapping during stress (PubMed:25736060).  Essential for the integrity and function of cytoplasmic messenger ribonucleoprotein (mRNP) complexes called stress granules (SGs) and processing bodies (PBs), sites of post-transcriptional gene regulation during stress (e. g.  salt and heat) (PubMed:25736060).  Involved in gibberellic acid (GA) biosynthesis and seed germination (PubMed:20396901).  Essential for stress tolerance, probably by regulating mRNAs entering the secretory pathway (PubMed:20484005).  Component of stress granules (SGs) that regulates growth under salt stress by modulating levels of GA20OX3 mRNA.  Binds GA20OX3 mRNA (By similarity).  May inhibit the degradation of mRNAs involved in stress adaptation (PubMed:26237081).
What are the official names of this protein?
Ribonuclease TUDOR 2, AtTudor2, TUDOR-SN protein 2, 100 kDa coactivator-like protein.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum. Cytoplasmic granule. Note=Accumulates heterogeneously in the cytosol, in patches around the nucleus and in the cell periphery, and relocates transiently to a diffuse pattern in response to salt stress (PubMed:20484005). Accumulates in cytoplasmic stress granules (SGs) and processing bodies (PBs) in response to abiotic stresses (e.g. salt and heat) (PubMed:25736060).
Protein: PYRG_TRIV2
Sequence: MTKFIFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINIDPGTMSPFQHGEVFVTQDGAETDLDLGHYERFTDTSMSRLNSVTTGSIYQAVIMRERRGDYNGGTVQVIPHITNEIKERILSVAKETNPSVVITEIGGTVGDIESLPFLEAIRQLRKQVGRQNVLYMHVTLMPYIASAGEMKTKPTQHSVKELRSIGIQPDILVCRSDRPIPRGLKQKLSEFCDVPVECVITSQDARSIYEVPLILEGEGLAEQTLKLLQMEQRQPNLEKWQAMVQGLYSPKHTVEIAIVGKYVSLGDAYLSVVEALRHAAIATQGDLQLRWINSEDLETQAPETYLAGVDGIVVPGGFGTRGVDGKIAAIKYARDRQIPFLGLCLGMQCSVIEWARNVGGLAGANSAEFDSTTKYPVINLLPEQQDVVDLGGTMRLGVYPCHILPNTLASKLYQAEIIQERHRHRYEFNNDYRQLLLDSGYVISGTSPDGRLVEIVEYPQHPFFISCQFHPEFQSRPNTPHPLFTGFVQAAIAQSHPTANFQTPVKVS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SEC1A_ORYSJ
Sequence: MSMDSVISSRSGADYRSFRQITRDRLLFEMLRSTKKSSKSAWKVLIMDKLTVKIMSFSCKMADVMEEGVSLVEDLYMRRQPLPLMDAIYFIQPTKENIRIFMSDMSGKIPLYKKAYVFFSSPVQRELVAQIKKDSNVRARIGALSEMNLEYFAIDSQGFTTDHDKALEELFSENAEGSLKYNSCLNMMATRIATVFASMREFPRVHYRVARTIDASTLTTLRDLAPTKLAAGVWNCLARFKAMIPEFPQTETCELLIVDRSIDQIAPIIHEWTYDAMCHDLLCMDGNKYVQQVPSKSGSGTENKEVLLEDHDPIWLELRHVHIANASERLHEKMTNFVSKNKAAQLHQARNGGDLSTKELQKMVQALPQYSDQIDKLALHVEIAGKLNSTIKEQQLKDVGQLEQDLVFGDAGTKELINFFRTHLDISRENKLRLLMVYAAINPDKTRSDKGAKLMQLAGLSADDMIAVSNMRCLCGHDSKKSSAGGFTLKFDLRKKRHGIRKERIGEESKWMLSRFYPILEELIEKLSKGELPKDEYHYLNDPSPSFRGIPSASTQTSPAHQPAQSMRSRRTGGTWARPRDSDDGYSSDSVLKHTSSNSRKLGQRLFVFVIGGATRSELCAAHKLSSKLKREIILGSSSLDDPPQFITKLKMLSTDDLTLDDLQI
What is the function of this protein?
Involved in the vesicle trafficking.  Binds syntaxins (By similarity).
What are the official names of this protein?
Probable protein transport Sec1a.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
Protein: MURA_DECAR
Sequence: MDKLLIEGGKVLSGEVAMSGAKNAALPILCASLLTSDPVHFTNVPHLNDISTMLRLLGDMGVGVTMDGIDGIVLNGGGLNNPVASYEMVKTMRASILVLGPLVARCGEARVSLPGGCAIGARPVDQHIKGLQAMGAEVKVEQGYVHAKATRLKGARICTDMVTVTGTENLMMAACLAEGETVIENAAREPEVVDLANCLVSMGARISGAGTDVIRIQGVDKLHGATHAIMPDRIETGTYLCAAAATGGDIRLLKTSAAYLDTVVDKLMDAGCEITVERDAIRLVAPKRLKAVSLRTAPYPAFPTDMQAQFMAINCIADGVATIRETIFENRFMHVNELMRLGANIQIEGNNAIVRGVDRLEGATVMATDLRASASLVIAGLVAQGETVIDRIYHLDRGYERIEEKLAKLGAAVRRVH
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARZ_STAAN
Sequence: MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDRK
What is the function of this protein?
Activates transcription of virulence factors alpha- and beta hemolysin genes (hla and hlb).  Also, activates RNAIII expression, a central regulator transcribed from the agr locus (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarZ, Staphylococcal accessory regulator Z.
What is the protein family that this protein belongs to?
Belongs to the SarZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_STAA3
Sequence: MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVT5_YEAST
Sequence: MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVNRHQLERGQVYFMVPHGDSQSHSPLTTLPIFVFAYTCHHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLYPNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFIENFRKGKLYDNRASFIPLDNFNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTSIKIFKYLSLSLFIWGIAVMVASLSAIVFLGTSSH
What is the function of this protein?
Probable amino acid transporter of unknown specificity.
What are the official names of this protein?
Vacuolar amino acid transporter 5.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.