PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_SHIB3
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SYR_PSEPK
Sequence: MKDTIRQLIQQALTQLVTDGVLPEGLSPAIQVENARDKTHGDFASNIAMMLAKPAGMKPRDLAEKLINALPASADISKVEIAGPGFLNFFQNTDALANRLDAALADAHLGARKAGPAQKVVIDMSAPNLAKEMHVGHLRSTIIGDSVARVLEFLGDNVIRQNHVGDWGTQFGMLMAYLQENPITSDELSDLENFYRAAKKRFDESEEFATRARGLVVKLQAGDPECLALWTRFKDISLSHCQKTYELLNVKLTMADVMGESAYNDDLANVVADLKAKGLLVEDQGAQCVFLEEFKNSDGDPLPVIVQKADGGYLYATTDLAAVRYRSNVLKADRALYFVDQRQALHFNQVFEVARRAGFVGHPMQMEHMGFGTMNGADGRPFKTRDGGTVKLIDLLTEAKERAYALVKEKNPSLADDELRHIGEVVGIGAVKYADLSKHRTSDYSFNFELMLNFEGNTAPYLLYAYTRVAGVFRKLGKGFDEVDGKIVLQAAHEQDLAARLAQFGEILNNVAEKGTPHVLCSYLYDLAGLFSSFYENCPILAAETPSQQQSRLRLAALTGRTLKQGLELLGLETLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y457_ATV
Sequence: MPPSSGQLLGDEEREPTSTPAIPEEGVYKVKYSNRRTNIVRLLPNGFQERKLRRLADLSAKLFNEVNYERRQQFFHEGKVDIKGTYKKYYEKYKEKLRTNAQAVLNKNNEAWSSFFSLLNLKKEGKLPQHIKHVSPPGYCKDRKTKKRKLILIVRQDRYKVDAENNKLILKDFNMEIEFVGRLRWYGKQGRLEIIFDETRNAWYAHIPVEVGVEETGKKSKHVVKGERKSIQIAKPKGNKVASIDLGINVIASVVVSDGTWLLYKGIRTKEDYFYFHKRIAEVQSLADRTRNIGEYEAYLELLREERRLFKKLKRRLLHLYRNLASHLIKTLHELGVSTIYLGNPFNIVQEKGDNFMTDKWPYRKLMHAIELKAQEYGMKVYEVDEYNTTKYCAYHDVKVKRNPRGVVICPKGHKLHSDLNGALNILKKAVGVVVNEVKKPLSFIVDHNRVAPIKGV
What are the official names of this protein?
TnpB-like protein ORF457.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transposase 35 family.
Protein: SYDND_THISH
Sequence: MRSHYCGSVNESHLDQEVTLCGWVNRRRDHGGVIFIDLRDREGLVQVVFDPDLPEVFATAERVRSEYVLKVKGRVRRRPAGTENPDLPTGAIEVLGRELTVLNSAETPPFQLDEDEVNEETRLRYRYVDLRRPAMQKRLQMRARVSRTLRRFLEDNGFLDIETPMLTKATPEGARDYIVPSRTHPGSFFALPQSPQLFKQLLMMGGMDRYYQIVRCFRDEDLRADRQPEFTQLDIETSFMDEEGIMGLMEEMVRELFAQVLEVPLHTPFQRMSYAEAMARYGSDKPDLRIPLELTELTDIMGEVDFKVFSGPARDPAGRVAALRVPKGGELSRKDIDDYTHFVGRYGAKGLAYIKVNDLNAGREGLQSPILKFMPDTVVVEILGRTGAEDGDLIFFGADKARIVNEALGALRVKLGHDLGLVERGWRPLWVVDFPMFEHDEKEGRWVALHHPFTAPRVERPEELTGNPGEMISRAYDMVLNGTEVGGGSVRIHTTAMQQAVFNLLGIGEAEARDKFGFLLDALKYGCPPHGGIAFGLDRLVMLMTGSQSIRDVMAFPKTQTAHCPLTDAPAEVSDAQLKELSIRVKKQTASG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMTR1_RAT
Sequence: MKRRTDPECTAPLKKQKRIGELARHLSSTSDDEPLSSVSHAAKASTTSLSGSDSETEGKQPCSDGFKDAFKADSLVEGTSSRYSMYNSVSQKLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLTLQGFDQELNVDWRDEPEPNACEQVSWFPECTTEIPDSREMSDWMVVGKRKMVIEDETEFCGEELLHSMLKCKSVFDILDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDRMFTNPLDSSGKPLLKESDIDLLYFADVCAGPGGFSEYVLWRRKWHAKGFGMTLKGPNDFKLEDFYSASSELFEPYYGEGGVDGDGDITRPENINAFRNFVLDNTDRKGVHFVMADGGFSVEGQENLQEILSKQLLLCQFLMALSVVRTGGHFVCKTFDLFTPFSVGLIYLLYCCFERVCLFKPVTSRPANSERYVVCKGLKVGIDDVREYLFSVNIQLNQLRNTDSDVNLVVPLSVIKGDHEFNDYMIRSNESYCSLQIKALAKIHAFVQDTTLSEPRQAEIRKECLQLWEIPDRARVAPSPSDPKFKFFELIKDTDINIFSYKPTLLTAKTLEKIRPVLEYRCMVSGSEQKFLLGLGKSQIYTWDGRQSDRWVKLDLKTELPRDTLLCVEIVHELKGEGKAQRKISAIHILDVLVLNGSDVREQHFNQRIQLAEKFVKAVSKPSRPDMNPIRVKEVYRLEEMEKIFVRLEMKLIKGSGGTPKLSYTGRDDRHFVPTGVYIVRTVTEPWTMAFSKGWKKKFFYNKKTGESFFTLPPESIAPFHTCYYTRLFWEWGDGFHMRDSQKPQDPDKLSKEDVLSFIQSHNPLGP
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs.  Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1).  Displays a preference for cap0 transcripts.  Cap1 modification is linked to higher levels of translation.  May be involved in the interferon response pathway.
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, Cap methyltransferase 1, Cap1 2'O-ribose methyltransferase 1, MTr1, FtsJ methyltransferase domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: YL263_MIMIV
Sequence: MSVVDKNYHKKTYHKYDHNKWVLIIYVKSVSHETNIDKFFYENTIDSLDSVINISSICLYTLNDQLSKILVDIQPKCKIPINLCVDSDNDILNTMKLHLDNNLSIIYFTNNTGFSVQQKQCHSLDCLSAYTTCIYDDLYSKVLNKFGLSKLITFDTLVVPNNNDSRKFIDNCIYFCRKLIGTDNEFKINLSLTITDSRMGYIVKDLETDLEIPNNNFVRNIVDKSFRQYLTEQFCSVKNNFKKCELPWKDDNFIYYPYLDMNVFPCDESVQNISYTSCNTNGFITNETNPFGKLFTRFNNPYEGVYLKKPQNNIQIPKHLHHIWIDEEPSINYINLWKTILVEPWKYTIWDNNSVLDLIKDTHWDQMYNCAKQSRQKQLIAMLSILEKYGGITINAYNIPLKSLDSLTIGNKFFVSFLAEDTGTSLSYRIIGSLPGGLGKNMIDPNISRKPYEGINNFFRSVNYNKTNDFVIPEIFDKLKSLLHVSVLNSNNTHNNFSKEIDYFLLSLSGQNIFIYPSYYFNANISTLPKRLSNKIIMINLQKYPDKKPIRIKTEVHRPYVVTKEAIADQLNENPKDKLKNIK
What are the official names of this protein?
Uncharacterized protein L263.
Protein: RPPH_ALBFT
Sequence: MLDREGFRPNVGIVLLNQKNQVFWGKRIRTHSWQFPQGGIDRGETPEQAMIRELHEEVGLLREHIRIVARTRDWLRYEVPDRYIRRDARGFYKGQKQIWFLLQLVGHDWDLNLRATDHPEFDAWRWNDYWVPLDAVVEFKRGVYEIALTELARYLPRNELRNRFLRQGVRPHEQETTFDAVPGANFELPPGGSFEPNPQTSYGLDASGKPHET
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: LAEA_CHAGB
Sequence: MAMDSQPFRGHIPNGVPPNRTYQEVYAENGRWYGTFKKGKYMFPIDESSWSRAEMRVIVLPSTTRKLLVYWTWVAGQVSGASTWPIIGPRVYAEIYRHLKPYYGYFEQVEIDWSPRSDDGSLRRDGYVVQWANELMDAMDSFGRPIRLDSNLTKQRLADVGFDEIKEEVIQLPLNGWPTEVHNRELGRWFNLGVRQAFQPLSLAPLCRGHGRTPAQVDELAEKARGEVYSNSVRAYCTFPSFAEPAGYAQVTPKSTIPAPFQRAWVGSREPQSGTCSVQRENGANGDRSTLSATGTFHVIRRIRAAQTPAAVGKRQDAG
What is the function of this protein?
Methyltransferase; component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:33766309).  Controls the expression of the chaetoglobosin A biosynthesis cluster via the cheR transcription factor and the subsequent production of chaetoglobosin A (PubMed:33766309).  Positively regulates the expression of smtA and negatively regulates the expression of velB (PubMed:33766309).  LaeA also regulates pigmentation and spores production (PubMed:33766309).
What are the official names of this protein?
Protein-methionine methyltransferase laeA, Secondary metabolism regulator laeA, Velvet complex subunit laeA.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
Protein: TPIS_WOLTR
Sequence: MSFLIVANWKMNGTRSLFVNFIGKLNDKSNEITSKLVICPPFTSLPGNIELNSNISIGAQNCHYKKSGSYTGEISAEMLKELGCTYVILGHSERTHETNGEIKLKSETAIESGLHPIICVGENLEDRESSKTKEVVEYQCKSRLPIHGEYTVAYEPIWAIGTGHVPSNNAIAEVIEVIQSYTSKKHVIYGGSVSLENIENLSNILNLSGVLIGSASLDFDRFHKIVQQVEKAY
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPM1A_RABIT
Sequence: MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEILKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW
What is the function of this protein?
Enzyme with a broad specificity.  Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling (By similarity).  Dephosphorylates PRKAA1 and PRKAA2.  Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB (By similarity).
What are the official names of this protein?
Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, PP2C-alpha, Protein phosphatase IA.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Membrane; Lipid-anchor. Note=Weakly associates at the membrane and N-myristoylation mediates the membrane localization.
Protein: OLF56_MOUSE
Sequence: MGIWLNESSVDGFILLGIFSQSQTDLLLFSTVMLVFTVALCGNVLLILLIYTDPRLHTPMYFFLSQLSLMDLMLVCNIVPKMAVNFLSGRKSISFAGCGIQIGFFVSLVGSEGLLLGLMAYDRYVAISHPLHYPILMSQKVCLQIAGSSWAFGILDGIIQMVAAMSLPYCGSRYIDHFFCEVPALLKLACADTSLFDTLLFACCVFMLLLPFSIIVTSYARILGAVLRMHSAQSRKKALATCSSHLTAVSLFYGAAMFIYLRPRRYRAPSHDKVVSIFYTVLTPMLNPLIYSLRNREVMGALRKGLDRCRVGSQH
What is the function of this protein?
Odorant receptor.  Activated by (+) and (-)-limonene.
What are the official names of this protein?
Olfactory receptor 56, Olfactory receptor 276-1, Olfactory receptor F7, Olfactory receptor G3, Olfactory receptor I-G7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAJ_BRUSU
Sequence: MKIDYYEALGVTRTADDKTLKAAFRKLAMQYHPDRNPDDPEAERKFKEIGEAYETLKDPQKRAAYDRFGHAAFENGGMGGGFGNGFGGAGGFADIFEDIFGEMMGGGRRRSNGGRERGADLRYNMEVTLEEAYAGKTAQIRVPTSITCDECSGSGAKPGSQPTTCTMCSGSGRVRAAQGFFSVERTCPGCNGRGQIIKDPCEKCHGQGRVTQERSLSVNIPAGIEDGTRIRLAGEGEAGLRGGPAGDLYIFLSVKPHEFFQRDGADLYCKVPISMTTAALGGQFEVSTLDGTQTRVKVPEGTQNGKQFRLKGKGMPVLRQSVTGDLYIQIDIETPQNLSKRQRELLEEFEKLSSQENSPKSAGFFSRMKEFFEGIGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_THEP1
Sequence: MKKLLIMLIRFYQRYISPLKPPTCRFTPTCSNYFIQALEKHGLLKGTFLGLRRILRCNPLSKGGYDPVPEEFSFKPRRRWS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PHNY_RHIME
Sequence: MTNAEVTIAVRHEPMRIAGRLVDTDDRVEVRYPWNDTVVGTVPAGRAEHAREAFAIAAAYQPKLTRYERQKILLATAEALAARKEEISDVITLELGISKADSLYEVGRAFDVFTLAGQMCIRDDGEIFSCDLTPHGKARKIFTMREPLTAISAITPFNHPLNMVAHKVAPAIATNNCVVVKPTELTPMTALLLADILYEAGLPPEMLSVVTGWPADIGMEMITNPHVDLVTFTGSVPVGKLIAANAHYKRQVLELGGNDPLIILNDLSDDDLARAADLAVAGATKNSGQRCTAVKRILCQESVADRFVPLVLERAKRLRFGDPMDRSTDLGTVIHEKAAALFEERVMRAAEEGADILYHPGRSGALLPPIVVDRVPHQSDLVLEETFGPIIPIVRVPDDDDATITLSNSTAFGLSSGVCTNDYRRMQKYIAGLKVGTVNIWEVPGYRIEMSPFGGIKDSGNGYKEGVIEAMKSFTNVKTFSLPWP
What is the function of this protein?
Plays an important role in phosphonate degradation by catalyzing the NAD-dependent conversion of phosphonoacetaldehyde (PnAA) to phosphonoacetate (PnA).  Has low in vitro activity with the related compounds phosphonopropionaldehyde (3-oxopropyl phosphonate) and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Phosphonoacetaldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: DXR_SYNE7
Sequence: MKAVTLLGSTGSIGTQTLDILEQYPDRFRLVGLAAGRNVALLSEQIRRHRPEIVAIQDAAQLSELQAAIADLDNPPLILTGEAGVTEVARYGDAEIVVTGIVGCAGLLPTIAAIEAGKDIALANKETLIAAGPVVLPLLQKHGVTITPADSEHSAIFQCIQGLSTHADFRPAQVVAGLRRILLTASGGAFRDWPVERLSQVTVADALKHPNWSMGRKITVDSATLMNKGLEVIEAHYLFGLDYDYIDIVIHPQSIIHSLIELEDTSVLAQLGWPDMRLPLLYALSWPDRLSTQWSALDLVKAGSLEFREPDHAKYPCMDLAYAAGRKGGTMPAVLNAANEQAVALFLEEQIHFSDIPRLIERACDRHQTEWQQQPSLDDILAYDAWARQFVQASYQSLESVV
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GLGA_CHLP8
Sequence: MARRNYKVLYVSGEVSPFVRVSSLADFMASFPQALEEEGFEARIMMPKYGIINDRKFRLHDVLRLSDIEVPLKEKTEMLHVKVTALPSSKIQTYFLYNEKHFKRSGLFSDLQLGGDHKGSAEKLIFFSVGVMETLVRLGWQPDIIHCNDWHAGLVPLLARTRYAKHDFFKKVKIVQSVHNVYRQGVFQPKMFQKHLDPEVFDGLEREGDDINLLATGIKYADLVTTTSPSYAKQIASDPESSFGMDKALKACKDRFHGILNGMDTRQWNPSSDKLIKKRYSAAQPELKLEDKKVLLEEVGLPFSEETPVVGVITTFDDVQGMGLLKESLSKLLELDLQLIVSGSGNKEFEQELRDLVEEHPEKLAVNTDFTDAFYHQMIAGLDMLIMPSRIESCGMKQMFAMNYGTVPIAYAGGGIVETIEEVSGDKGTGFVFTDYTAEALTAKLGEALSMFDDKERWAELMREGMERDFSWSASAEQYAELYREILG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: YIDC_THEMA
Sequence: MVLRKVVAILLAILPIFLFAVEPIKVVRSEKEIVVLTRFEEYHFDLEKGILKDFYTLVDGRKHVFTYGNDGFDVLDEGTPLTVIEEPIVTGVGKVSEGFSDEVSIVYNYGYVKKIFTIKNNENYTFFVDIESSKPVDVTVPRVSVDTSTDRYLENYFASFNPKTRTLVLLKHDEGLLFEGTLKVNGQKRFIVFMGPNKRTLIKKAFPEDYDVLIKALVNIPGFNKWYDSVFYGLVWFFWWLKDLTKNFGWAIMLFTLIVRLILYPLYHAQTKSLINMRKLQPQIEAIKKKYKDPTKQQEALLKLYREAGVNPASGCLMLLIQLPIFMLLWSVIRYYVEEFAYSGSFLIWKDLSAGGFSNNWLFLVITIVASYYTTLLTSQDARTAWQGIIMSVIFPFLFVGLPSGLFLYYATNTLIQLAVTYYTYKRYKIKGLTTRELLGLPKKA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAB_SHEDO
Sequence: MSKKLHIKTWGCQMNEYDSSKMADLLDEYQGYTLTDDATEADVLLLNTCSIREKAQEKVFHQLGRWKTLKDKKPGLIIGVGGCVASQEGKAIKDRAQCVDIIFGPQTLHRLPEMIDQVQRGEKVVIDVSFPEIEKFDRLPEPRADGPTAFVSIMEGCSKYCSFCVVPYTRGEEVSRPQDDIILEIAQLAEQGVREVNLLGQNVNAYRGATHDDQICTFAELLRLVASIDGIDRIRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDRILTQMKRGHMAIEYKSIIRRLRKAREGIQISSDFIIGFPGESAEDFADTMKLIEDVAFDHSFSFIYSARPGTPAADLPDDVSDEEKKQRLAILQDRITQQAMRYSRQMLGTVQRILVEGPSVKNPMELRGRTENNRVVNFEAPHTHIGSFVDVEIVDVYTNSLRGIFIRGEAEMDLRRSLRPADILAKHKQDDVLGVTQFTP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBDD_ECOL6
Sequence: MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTYEEFFRERQDARYGGKGGARCC
What are the official names of this protein?
Uncharacterized protein YbdD.
What is the protein family that this protein belongs to?
To E.coli YjiX.
Protein: FNTB_PEA
Sequence: MEASTAAETPTPTVSQRDQWIVESQVFHIYQLFANIPPNAQSIIRPWLCYWIIHSIALLGESIDDDLEDNTVDFLNRCQDPNGGYAGGPGQMPHLATTYAAVNTLITLGGEKSLASINRNKLYGFMRRMKQPNGGFRMHDEGEIDVRACYTAISVASVLNILDDELIKNVGDFILSCQTYEGGLAGEPGSEAHGGYTFCGLAAMILIGEVNRLDLPRLLDWVVFRQGKECGFQGRTNKLVDGCYSFWQGGAVALLQRLHSIIDEQMAEASQFVTVSDAPEEKECLDGTSSHATSHIRHEGMNESCSSDVKNIGYNFISEWRQSEPLFHSIALQQYILLCSQEQDGGLRDKPGKRRDHYHSCYCLSGLSLCQYSWSKRPDSPPLPKVVMGPYSNLLEPIHPLFNVVLDRYREAHEFFSQL
What is the function of this protein?
Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins.  The beta subunit FTB is responsible for peptide-binding.
What are the official names of this protein?
Protein farnesyltransferase subunit beta, FTase-beta, CAAX farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit beta family.
Protein: BCAT1_ARATH
Sequence: MALRRCLPQYSTTSSYLSKIWGFRMHGTKAAASVVEEHVSGAEREDEEYADVDWDNLGFSLVRTDFMFATKSCRDGNFEQGYLSRYGNIELNPAAGILNYGQGLIEGMKAYRGEDGRVLLFRPELNAMRMKIGAERMCMHSPSVHQFIEGVKQTVLANRRWVPPPGKGSLYLRPLLFGSGASLGVAAASEYTFLVFGSPVQNYFKEGTAALNLYVEEVIPRAYLGGTGGVKAISNYGPVLEVMRRAKSRGFSDVLYLDADTGKNIEEVSAANIFLVKGNTIVTPATSGTILGGITRKSIIEIALDLGYKVEERSVPVEELKEAEEVFCTGTAAGVASVGSITFKNTRTEYKVGDGIVTQQLRSILVGIQTGSIQDTKDWVLQIA
What is the function of this protein?
Converts 2-oxo acids to branched-chain amino acids.  Acts on leucine, isoleucine and valine (By similarity).
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase 1, mitochondrial, Atbcat-1.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GOX1_MAIZE
Sequence: MGEITNVMEYQAIAKQKLPKMAYDYYASGAEDEWTLQENREAFSRILFRPRILIDVSKIDMTTTVLGFKISMPIMVAPTAMQKMAHPDGEYATARAAAAAGTIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRKVVEQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPHLTLKNFEGLDLGKMDQAADSGLASYVAGQVDRTLSWKDVKWLQTITTLPILVKGVLTAEDTRLAVANGAAGIIVSNHGARQLDYVPATISALEEVVKAARGQLPVFVDGGVRRGTDVFKALALGAAGVFVGRPVVFSLAAAGEAGVSNVLRMLRDEFELTMALSGCTSLAEITRKHIITESDKLSAIPSRL
What is the function of this protein?
Catalyzes the oxidation of glycolate to glyoxylate, with a reduction of O2 to H2O2 (PubMed:25416784).  Is an essential enzyme in photorespiration in plants (PubMed:18805949).  Photorespiration plays a vital role in C4 photosynthesis in Z. mays and is essential for maize seedling development and maintaining low (non-toxic) levels of glycolate (PubMed:18805949).
What are the official names of this protein?
Glycolate oxidase 1, GOX.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: AMELX_HUMAN
Sequence: MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPSTDKTKREEVD
What is the function of this protein?
Plays a role in biomineralization.  Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development.  Thought to play a major role in the structural organization and mineralization of developing enamel.
What are the official names of this protein?
Amelogenin, X isoform.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: KUP1_SINMW
Sequence: MSQLSAPGAENTRRLLAMALGSVGVVYGDIGTSPLYAFREALRPVSHDGVTDVEIVGLISLMIWALTIIVTIKYVLFLLRADNQGEGGTLSLLALLMKTANGHTAILFFMGIAGAALFIGDAMITPALSVLSAVEGLKLVTPALSDYVVPIAVVILLFLFAVQSKGTAAVSKFFGPITLVWFLVMGAVGFMHIADDLSIFRAFNPYYAVAFLFNEGYVGIVVLGAVFLTVTGAEALYADLGHFGRRPIQWAWFTVVFPALTLNYLGQGAFVLKNPEAMSDPFFLMFPKWALLPAVILATAATIIASQAVITGAFSLTRQAIHLGFLPRMAIFHTSETHTGQIYLPNVNTLLMFGVMALVFIFGSSESLATAYGISVTGAMVVTTVLAFEFLRMRWNWPAWWAAGVLLPLFALELVFLGANMLKIHDGGYVPILIAATFIVIMWTWKRGTAILHTKTRHIDIPLERFIKSIERQSEHAPVSVPGTAIFLTSDPESTPAALLHNIKHNHVLHQQNFILTIRTANTPKVPREERVSARRLSERFTLMEVRFGFMETQNVSQALGLFRKSGLKFDIMSTSFYLGRRKLVPDAQSGMPHWQDRLFIALANAAIDPSDYFRLPTNRVVELGSHVII
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: S22FL_XENTR
Sequence: MDLDEAFLYIGEFGCCQKRLTAFLTLLQVYVACQSMLIVLVGAVPEYLIDNEDISASKEEYTKHLHDTNNFTSIVSEWHLIKNEAYKVNLASSLFFAGLLIGNILFGPLSDKLGRRPVYLSGLFFDITFGYCTALAPSYEVFAVSRFFVGIMNGGMALVSFVLTQEYVGKSYWALTGSLTNLIFAVGIAFYALLGFYIRNWRTLAFVANSPGIFFFLLSFLLPESPRWLYSHGYTTEAEGVLQSMAVGNGVERPVVKLKSCPGTSSKSAHSVFDLVKYGVLRWRTILLMYIWYVCSLVYYGLTLNAGELKGNLYLNVALYGLVEVPAFPLCLYFIEKSWSGRRKATAGFLGFAGFACIFTIFLPETNGDLLNPTVLALFGKLSVSAAFNVVYIYTSELYPTVVRNAGLGVCAMACRFGGILSPFIPTMKSLNPSMPFVAFGISGISAGILSLLLPETRNKPIAESIEDLQSPAYQLLSRGNEVLAST
What is the function of this protein?
Probably transports organic cations.
What are the official names of this protein?
Solute carrier family 22 member 15-like.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.