PharMolix/UniProtQA huggingface dataset:
Protein: TDH_SALPK
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDDWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSX_STRP2
Sequence: MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVIFNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKSVTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANAPNDVKTIAEDAKKIEGVSEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMRLVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPDLFSPLMIALLFVIGVFIGSLGSGISMRRFLKI
What is the function of this protein?
Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.
What are the official names of this protein?
Cell division protein FtsX.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS2_PROMA
Sequence: MAVVTLSEMMEAGAHFGHQTRRWNPKMSRYIYCARNGVHIIDLVKTAVCMNNAYKWTRNAAKSGKRFLFVGTKKQASEVVAQEAARCGASYVNQRWLGGMLTNWTTMKARIDRLKDLERMESSGAIAMRPKKEASVLRHELERLQKYLGGLKGMKRLPDVVVLVDQRRETNAVLEARKLDIPLVSMLDTNCDPDLCEVPIPCNDDAVRSVQLVLGRIADAINEGRHGSNDQRARQKYS
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PRP5_CRYNB
Sequence: MPRSPYRSSNRSYRSPSPSRYDRSHPSSSSRRQDDRKASRYDDDYSRDRERDRERERDRTRDYRDRDRDYDRRRDKDRYRDDDRDRRRRDDKDDRRREERDRGSDRKRDSERRSPMSTIRVDPIVSLASPVPETEEEKKRKAKERLETWKRQRALKEGKSAAATPEPKSTAPPPVTSGLPPKPTAFSLSRIGLPLKPTNPTPLKRSMAALDDEDTSDRKLQKLDLPDFDPEVQSGDAAQVGSIGADLAVADGDEDDDTVVKKEEEKEEKMDIDKKAEEDEEEDPLDAFMRDNVQQVVEVNKADAKRMGLRVAEDGSDDENQGQVVEKDKLAEAEALLQQAAAKSRKKDLPPPDHSKIDYEPFRKAFYVPPVEVLEMDEEEAELVRLEMDGIKIRGQDAPKPVRNWGAFGLPQGCLDVIKHQGWETPTSIQAQAIPAIMSGRDVIGIAKTGSGKTVAFLLPMLRHVRDQRPVSGSEGPIAVVMSPTRELASQIYKECQPFLKVLNIRASCCVGGSSISEDIAAMKKGAEVVICTPGRMIDLLTANNGRVTNVRRTTYIVMDEADRMFDMGFEPQVMKIINNVRPSAQKVLFSATFPKTMESLARRILVKPLEITVGGRSVVAPEIDQRVEVRDGDTKFTRLLEILGEMGEEHKDEDDFRTLIFVDRQESADDLFRELLQRGYVCASLHGGKEQVDRDEAIKNFKNGDVPIIVATSVAARGLDVKELKLVINYDAPNHMEDYVHRAGRTGRAGNKGTCITFITPEQERFSVDIVRALEASKAFIPDDLKKMSDSFLGKIKSGKARAAGSGYSGKGLERIERRREEKDRAEKTTYGDTSEALSLSSREGAVIPYKAKTNEFKPPETSHKGEADYTFTEIKVDIVNGPAPDRVSSQPVFNPKNAVASLPAQTLAALEKAKKEGRGVDAANLANVVAKLTQSIELTKAEKLGLAAATSAPRLAPGARTKDPDATDWHAIFPINDYPQKARWKATNKEQMTLLQEVSGASITMRGRFYPPGEEPALGGEPKLSLLIESNDEMRVRAAVEEIRRVLVEGSVQALNAVDRAGASGGRYAV
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase PRP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDUB6_PANTR
Sequence: MTGYTPDEKLRLQQLRELRRRWLKDQELSPREPVLPPQKMGPMEKFWNKFLENKSPWRKMVHGVYKKSIFVFTHVLVPVWIIHYYMKYHVSEKPYGIVEKKSRIFPGDTILETGEVIPPMKEFPDQHH
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6, Complex I-B17, CI-B17, NADH-ubiquinone oxidoreductase B17 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB6 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: MNMA_HELMI
Sequence: MKETVVVAMSGGVDSSVTAALLLEQGYDVIGVTLQIWPKDAPEGAEGGCCSLSAVEDAKRVASKLGVPHYVLNFRDYFETEVIEYFGREYLAGQTPNPCIRCNRVIKFEGLLQKSLALGAAKVATGHYARIEQDSATGRYRLGRGIDANKDQSYALFNMTQEQLSRTLFPLGGFTKPEIREKAAQLGLAVASKPDSQEICFIPDNDYRRFLEERYPDHRFQPGPFVDQEGNVIGTHRGLPFYTVGQRKGLGVAFGFPAYVIALDVEHNAVVIGPDEAVKGRRLLADDLNWIDIAGLKAPMEVEAKIRYSASPAIAVISPVKDGSAVIVEFAAPQRAITPGQAVVFYRGDWVVGGGTIVRNLDLKLPEIRHPEPKPVKGVKAKGRV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_ALIB4
Sequence: MARKIPLHRVRNIGIAAHIDAGKTTTTERILFYTGVSHKIGEVHEGAATMDWMEQEQERGITITSAATTCHWNHPKTNEQLQVNIIDTPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVWRQANKYGVPRIIYVNKMDRTGANFFNVEAQVRDRLKANPVPIQVPIGAEENFRGMVDLIKMKAYTYNLDAQAGEMYKIEDIPADLEDVVAEYREKLIEAAAESSEELMEKYLEGTELTEDEIVAGLKKRCLAMEITPMVCGTSFKNKGVQPLLDAVAMYLPAPTEVADIKGETQDGDAIIVPSTDKGEVAALAFKIMTDPFVGQLTFTRVYRGVLESGTYVLNSTKMKKERIGRLLKMHANSREEIKELYAGEIGAVVGLKDTITGDTLASEKDPVILERMDFPDPVISVAVEPKTKADQEKMGIALGKLAEEDPSFRVNTDEESGQTIISGMGELHLEILVDRMKREFKVEAEVGAPQVAYRETIRNAVKQEYKYAKQSGGKGQYGHVYLEIKPLPSGSEPNFKFNNEIKGGVVPKEYIPAVEKGCAEAMLGGILAGYPMVDIEVTLYDGSYHDVDSSEMAFKLAASMGFKQGCRSAAAGAVILEPIMKVEIETPEDYMGDVIGDCNKRRGQVQSMDDRAGIKLVTAMIPLSEMFGYSTDLRSMSQGRATYSMIFDAYQEVPRNVSEEIMKKRNG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC14_CANAL
Sequence: MHSSSVHVPLIEFLKNRIYLGAYDHHKRDTEDLAYFTVEDALPYNAFYMDFGPLNIGHLYRFAVLLHKKLNEDSTQGKGLVIYSSTSPKERANLACLLCCYMILLQNWAPHQVLQPIAQITPPLQAFRDAGYSSADYEITIQDVVYAMWRAKERGMIDLAKFDLDEYEQYERVDQGDFNVISKDFIAFASPQQSKRGGLNEPFQKVLEYFVENNVQLVVRLNSHLYDAKEFTKRNIKHIDMIFDDGTCPTLEYVQKFIGAAECIINKGGKIAVHCKAGLGRTGCLIGAHLIYTHGFTANECIAYMRMIRPGMVVGPQQHWLYLHHDDFRSWRHTMIVDNRPDPLIGNLFPLCSYEDYKQRLKEAKRKERLQLQQQLTSPLADSSVINTPIRRRKVSGALASKIQTVVPIESPGQPRKYFEDSEDIDEVEMVNNSDDENTMQDIIQSSPARYDSVTPKTKDNSDWRVLRSISTNNVSSQQSIHIIKTTTTKTVNETLSSPPGTSPTNVLRVSKARSKNRIASGNSQTSRAHSGGVRKLSGKKH
What is the function of this protein?
Protein phosphatase which antagonizes mitotic cyclin-dependent kinase CDC28, the inactivation of which is essential for exit from mitosis.  To access its substrates, is released from nucleolar sequestration during mitosis.  Plays an essential in coordinating the nuclear division cycle with cytokinesis through the cytokinesis checkpoint.  Involved in chromosome segregation, where it is required for meiosis I spindle dissambly as well as for establishing two consecutive chromosome segregation phases (By similarity).  Plays a role in the expression of hydrolase genes such as CHT3 and ENG1 involved in septum degradation after cytokinesis.  Also required for ACE2 localization to the daughter nucleus.  Required for invasive and hyphal growth.
What are the official names of this protein?
Tyrosine-protein phosphatase CDC14.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Bud neck. Cytoplasm, cytoskeleton, spindle pole. Cell septum. Note=Does not accumulate in the nucleolus in interphase cells. At the G1-S transition, starts to accumulate both in the nucleolus and the and the DAPI-staining region of the nucleus. At the S-G2 transition, starts to concentrate as faint foci on the nuclear periphery. In early mitosis, the CDC14 nuclear signal diminishes concentrates to the spindle pole body (SPB). During cytokinesis, the localization at the SPBs gets fainter and the protein is preferentially found at the septum region. In yeast forms, in which cell separation takes place after cytokinesis, CDC14 is present at the bud neck; in hyphal forms, in which cell separation is inhibited, no CDC14 signal is detected.
Protein: REP_BPFD
Sequence: MIDMLVLRLPFIDSLVCSRLSGNDLIAFVDLSKIATLSGMNLSARTVEYHIDGDLTVSGLSHPFESLPTHYSGIAFKIYEGSKNFYPCVEIKASPAKVLQGHNVFGTTDLALCSEALLLNFANSLPCLYDLLDVNATTISRIDATFSARAPNENIAKQVIDHLRNVSNGQTKSTRSQNWESTVTWNETSRHRTLVAYLKHVELQHQIQQLSSKPSAKMTSYQKEQLKVLSNPDLLEFASGLVRFEARIETRYLKSFGLPLNLFDAIRFASDYNRQGKDLIFDLWSFSFSELFKAFEGDSMNIYDDSAVLDAIQSKHFTITPSGKTSFAKASRYFGFYRRLVNEGYDSVALTMPRNSFWRYVSALVECGIPKSQLMNLSTCNNVVPLVRFINVDFSSQRPDWYNEPVLKIA
What is the function of this protein?
Isoform G10P protein binds to double-stranded DNA and prevents hydrolysis by nucleases.  Additionally, G10P is an inhibitor of DNA replication and may have a role in the transition from semiconservative replicative form DNA replication to single-stranded DNA synthesis in the life cycle.
What are the official names of this protein?
Replication-associated protein G2P, Rep, G2P, Gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus G2P protein family.
Protein: TRPA_BURM1
Sequence: MSRIQQTFAALAQQGRKGLIPFITAGDPDPAKTVEFMHALAAGGADVIELGVPFSDPMADGPVIQRSSERALARGVTLKHVLADVKRFRETNQTTPVVLMGYANPIERHGVDAFAADARAAGVDGVLVVDYPPEEAAVFAEKMRAAGIDPIFLLAPTSTDARIAEVGKIASGYVYYVSLKGVTGAGNLDVSSIAGKIPAIKSRVPVPVGVGFGIRDAETARAVAEVSDAVVIGSRLVQLLESAAPEGAVAALQAFIAELRAALDGAANTAR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: NDUF7_MOUSE
Sequence: MNALVRRCVARAGLPCIWRGKCYSSGNEPAESNQVTPMLRHLMYKIKSTGPITVAEYMKEVLTNPAKGYYVHQDMLGEKGDFITSPEISQIFGELLGVWFVSEWIASGKSPAFQLVELGPGRGTLTADILRVFSQLGSVLKTCAISIHLVEVSQKLSEIQALTLAEEKVPLERDAESLVYMKGVTKSGIPVSWYRDLKDVPEGYSLYLAHEFFDVLPVHKFQKTPRGWREVFVDVDPQASDKLRFVLAPCATPAEAFIQRDERREHVEVCPDAGVIIQELSQRIASTGGAALIADYGHDGTKTDTLRGFYGHQLHDVLIAPGTADLTADVDFSYLRRMAQGKVASLGPVEQRTFLKNMGIDVRLKVLLDKAGEPSAKQQLLGGYDMLMNPQKMGERFHFFALLPHQRLHGGSQERNACQSKTPSSSVAGFDELVWQ
What is the function of this protein?
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).  Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex.
What are the official names of this protein?
Protein arginine methyltransferase NDUFAF7, mitochondrial, NADH dehydrogenase [ubiquinone] complex I, assembly factor 7, Protein midA homolog.
What is the protein family that this protein belongs to?
Belongs to the NDUFAF7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYC6_MICAE
Sequence: DGASIFSANCASCHMGGKNVVNAAKTLKKEDLVKYGKDSVEAIVTQVTKGMGAMPAFGGRLSAEDIEAVANYVLAQAEKGW
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: RFTN1_MOUSE
Sequence: MGCSLNKLEKREEKRPGNIYSTLKRPQVETKVDVTYEYCFLEFTTLTAAELPRSSATRLASLRDLPDQLLELYQQGFSLAALHPFVQPTRRQEKILLEHIFRAILVKKTNRSQKAELHDEGYTLELDYCSSLEHLADQKLIPEFIKKVQEAASQGLKFVSVVPQYQPSVSSAGSRRLKPVANSVEDARDVKCTLGDRSSLENDTPKAAETDAATAGVNRRPETKPGSTGDVPSAQQPGIPSPSAENEAGEFPLRGLQPALDRSEGDPSNGPEELPSRKMEIFAFFNRPKSQQKCRQYYPVTIPLQVSKNGQTVSSLDASWLEHMSDHFRKGGVLVNAVFQLGMANDSFYGLTDGVFIFEAVSTEDNRTTQGYDAIVVEQWTVLEGTEVQTDYMPLLNSLAAYGWQLTCVLPTPILKTTREGNVSTKQIVFLQRPCLPQKTKKRESKFQWRFSRNEIHGRQTRKSKGKLSASNKQQAEENEKNLEDQFSKAGDVGNCVLGAPQWGRASEVREQRQGSAAVQNGPAGHNRDSVALRHSNPRAEAELAAGPTPTEAN
What is the function of this protein?
Involved in protein trafficking via association with clathrin and AP2 complex (By similarity).  Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195).  Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (PubMed:19414744).  May regulate B-cell antigen receptor-mediated signaling (By similarity).  May play a pivotal role in the formation and/or maintenance of lipid rafts (By similarity).
What are the official names of this protein?
Raftlin, Raft-linking protein.
What is the protein family that this protein belongs to?
Belongs to the raftlin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cytoplasm. Membrane raft. Endosome. Early endosome. Note=Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3. Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195).
Protein: AICDA_MOUSE
Sequence: MDSLLMKQKKFLYHFKNVRWAKGRHETYLCYVVKRRDSATSCSLDFGHLRNKSGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAEFLRWNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIGIMTFKDYFYCWNTFVENRERTFKAWEGLHENSVRLTRQLRRILLPLYEVDDLRDAFRMLGF
What is the function of this protein?
Single-stranded DNA-specific cytidine deaminase.  Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA.  Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses.  May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
What are the official names of this protein?
Single-stranded DNA cytosine deaminase, Activation-induced cytidine deaminase, AID, Cytidine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly cytoplasmic. In the presence of MCM3AP/GANP, relocalizes to the nucleus.
Protein: RR4_FRESP
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTNNKQRSKALIQNFIASSPRQEELPNHLTIDPFQYKGLVNQIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL19_VIBVY
Sequence: MSNIIKALEQEQMKQDLPKFAPGDTVVVQVKVKEGNRERLQAYEGVVIAIRNRGLHSAFTVRKISNGEGVERTFQTHSPVVDSIEVKRRGAVRRAKLYYLRERSGKSARIKEKLAKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL22_MESM1
Sequence: MESRATVKVQRISARKARLVADLIRYKSANDALSILYNTNKKASALFIKLLNSAVANAINNHGMNNEKLVVEKVLVNEGPTLKRFQPRSQGRAYSIFKRTSHLEIVLKEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ATP8_CERCA
Sequence: MPQMAPIGWLSLFIIFSLTFILFSMMNYYSTIPQSPKSQILKKSQTNSMNWKW
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: LYSK_PYRHO
Sequence: MISEEEKIKFLKELVEIYSPTGREEEAAKFIKEKFEEYGIEAYVDNVGNVIARKSGEGPLVLLAGHIDTVPGYIPVRIEGEVLWGRGSVDAKGPLATLFFSTIEGNANVIFAGLVDEEGFSKGARNLKIPRPDYIIVGEPSGTNGVTIGYKGSLTVRFVERVEKVHSSLGVGAAERLIEKWLEISKDFSDGFNGLNGRIVRFLAYDREFEFYGEMIINLRTPPGYVPPLEWDIIDFVPAYEVDRRSPLVRAFVKSIREAGLKPKLKKKSGTADTNILGPKFGVDAVAYGPGDSKLDHTPYERINLREYLKSIEILKAVLRKLKGG
What is the function of this protein?
Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
What are the official names of this protein?
Putative [LysW]-lysine/[LysW]-ornithine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. LysK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCD_MYCTU
Sequence: MTHMSIFLSRDNKVIVQGITGSEATVHTARMLRAGTQIVGGVNARKAGTTVTHEDKGGRLIKLPVFGSVAEAMEKTGADVSIIFVPPTFAKDAIIEAIDAEIPLLVVITEGIPVQDTAYAWAYNLEAGHKTRIIGPNCPGIISPGQSLAGITPANITGPGPIGLVSKSGTLTYQMMFELRDLGFSTAIGIGGDPVIGTTHIDAIEAFERDPDTKLIVMIGEIGGDAEERAADFIKTNVSKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAAAKQEALEAAGVKVGKTPSATAALAREILLSL
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
Protein: BACH1_MOUSE
Sequence: MSVSESAVFAYESSVHSTNVLLSLNDQRKKDVLCDVTVLVEGQRFRAHRSVLAACSSYFHSRIVGQTDAELTVTLPEEVTVKGFEPLIQFAYTAKLILSKDNVDEVCRCVEFLSVHNIEESCFQFLKFKFLDSTSEQQECARKKCFSSHCQKADFKFSFSEQKDLEIDEADEFLEKKRVQTPQCDSRRCQGSVKASPPLQDSVSQACQSLCTDKDGALALPSLCPKYRKFQKAFGTDKIRTLESGVRDVHTASVQPNETSELECFGGAQGCADLHVILKCEGMKAAMESEDTEGQDPSPQCPAEQPQGTPLPQDSAGPHGLYSLSALHTYEQSGDVAFAGVQSKTVKTEKPLSRPDAQDEKPSENQDLYLKSSMGPKEDSSSLASEDRSSVEREVAEHLAKGFWSDICSTDSPCQMQLSPTVAKDGPEQGYSQRRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSSEGCSSNLEIGNYDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQDCEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQSEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSPEQIQILAKYSASDCPLSFLISEKGKSTPDGELAFTSVFSVSDVPPTAPPPCGRGSSAASQELVQESPPTTAAAPEQATLLEPCRQSAGISDFCQQMSDKCTTDE
What is the function of this protein?
Transcriptional regulator that acts as repressor or activator, depending on the context (PubMed:8887638, PubMed:19170764).  Binds to NF-E2 DNA binding sites (PubMed:8887638, PubMed:19170764).  Plays important roles in coordinating transcription activation and repression by MAFK (PubMed:8887638).  Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (By similarity).
What are the official names of this protein?
Transcription regulator protein BACH1, BTB and CNC homolog 1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. CNC subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDH_CHLP8
Sequence: MKITVIGAGNVGATTAFRIADKKLARELVLLDVVEGIPQGKGLDMYETGPVGLFDTKITGSNDYADTADSDIVIITAGLPRKPGMTREDLLMKNAGIVKEVTDNIMKHSKNPIIIVVSNPLDIMTHVAWVRSGLPKERVIGMAGVLDAARFRSFIAMELGVSMQDINACVLGGHGDAMVPVVKYTTVAGIPISDLLPAETIDKLVERTRNGGAEIVEHLKQGSAFYAPASSVVEMVESIVLDRKRVLPCAVGLEGQYGIDKTFVGVPVKLGRNGVEQIYEINLDQADLDLLQKSAKIVDENCKMLESTIG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: SPEE_ECOBW
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDALASQPS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_VIBPA
Sequence: MQTKNKQGVLLVNLGTPDEPTAPAVKRFLSQFLHDHRVVDMTRWLWCPILHGVILPIRSPKVAKLYESVWMEEGSPLMVYSKRQAKKLAQHLDMPVELGMTYGNPSLQSGFEALIAQGVEEVIVLPLYPQYSGTTTAAVSDGITKAFKQLPVMPAFSFIRDYHDHPMYIEALAHSVRQYWEEHGKGDYLLCSYHGIPKRYADNGDIYPQHCEATTRLLGEALGLSSDQIGMAYQSRFGREEWLQPYTDKTLETITSKGVKKIDIMTPAFSSDCLETLEEIAGENKEIFMEAGGEQFHYIPCLNDDDMHIDMMAELVRSKL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.