PharMolix/UniProtQA huggingface dataset:
Protein: PYRH_AERPE
Sequence: MESVVVKISGSLVHPPRLDYLTRLRDVLWGLVDGGFRVAVVVGGGGLARSYIDVLRRAGVSEALLDEMGIESSRLNASLLAKLLYPRSQPYPLASLREVLEVFMTGLIPVSGGFQPGQSTNAVAAVIAEALGARTLLNCLKGVEGVYSDEPSTPGARLLRRLTYRQLEDILVKVSSQRAGSYTLWDMVALSVARRSGLRIVFFDCSDPANIWGALKGEKGSIVEG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_FLAJ1
Sequence: MTKLSVNINKIATLRNARGGNVPDLLKVAADIQRFGGQGITIHPRPDERHIRYQDARDLKAIVTTEYNIEGNPQHNFIDLVLECKPDQVTLVPDAIGAITSSAGWDTIKNQEYLKEVIQEFQRNGIRTSIFVDPVLEMIEGAKKTGTDRIELYTEAFAHQYDLGNKNGIDPYVKAAELANELGLGINAGHDLSLDNIQFFKQNIPGLLEVSIGHALISEALYLGLDNVVNMYLKKLK
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE6_HPV32
Sequence: MASTSASSQPSTLYQLCKDFGLTLRNLQICCIWCKNHLTSAEAYAYHFKDLHVVWKKGFPYAACAFCLEFYSKVCALRHYDRSAFWHTVEQETGLLLEEQIIRCAICQKPLSPSEKDHHIYNGRHFRFILNRWTGRCTQCRE
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Sequesters tumor suppressor TP53 in the host cytoplasm and modulates its activity by interacting with host EP300 that results in the reduction of TP53 acetylation and activation.  In turn, apoptosis induced by DNA damage is inhibited.  E6 protects also host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: TIG_STUS1
Sequence: MQVSVESTSALERRMTIGVPVERIETEVNKRLQQTASRAKIPGFRPGKVPMSVIRQRYEEAARQEALGDLIQSTFYEAIVAEKLNPAGAPSVEPKVFEKGKDLEYVATFEVFPEFEVAGFEAIEIERLQAEVTDADVDNMLEILRKQNTRFESVERAAENGDQVNIDFVGKIDGEAFAGGSAKGTQLVLGSGRMIPGFEDALVGAKAGEERVITPTFPEDYQNLDLAGKTAEFTVTVNSVAAPQLPELNEEFFAQFGVQEGGVEGFRAEVKKNMERELRQAIKTKVKNQVMEGLVAGNPIEVPKALVDNEVNRLRVQAVQQFGGNIKPDQLPAELFQEQAKRRVVLGLIVAEVVKQKELKPDEARVRELIEEMASAYQEPEQVVAWYYKNAEQLNEVRSVVLEEQVVDTVLQQAKVTDKSVSYEEAVKPAEAPQAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
Protein: TPM1_CHICK
Sequence: MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEERSKQLEDELVALQKKLKGTEDELDKYSESLKDAQEKLELADKKATDAESEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAQKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERAEERAELSESKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers.
Protein: GREA_THEAB
Sequence: MKKESIYLTKEGYEKLKAELDQLKQKLMFEIAQRIKEARELGDLSENSEYQEAKNEQGRIAARINELENMLSKAEVIEGLDTNVINIGNWVLIKNLDTGEEKTIQIVTPHEADVFNNKISFESPIGRVLVGKKVGEVVKIKAPKGVFKYQILGIKI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: FMT_MACCJ
Sequence: MSKIIFMGTPDFSAPILKALHEAHGVSLVITQPDKPVGRKRVLTPPPVKVMAESLGIEVYQPESMKSDEAFERVHALSPDLIVTAAFGQILPERVLDIPRLGCINVHASLLPKYRGGAPIHKAIINGEKYSGVTIMYMVKRLDAGDMIDSVQVPIEINDTVGTLHDKLSVAGTDLLLEVMPSVLSGTNNRTPQNDSEATFASNVSREEEYVTFDRTALEVHNHIRGLSPWPVAFANFDGKAMKLWASEIAEGSGAPGEIIQADKAGLVIATNDGAVRITSLQPAGKKRMDAASFVAGAKSQLVGMKFNEA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RSMH_NITSB
Sequence: MNAPHKPVLLNEVLESFKDRKGTIVDATLGYGGHSEALLKSNPDIKIVGIDQDSEAIAFSKQRLASYGDRVQIIQGRFADVIEDILQTHDVQGVLADIGVSSLQLDKKDRGFSIHSENLDMRMDQNAELSAYHVVNTYDEEELKRIFKEYGEIRHSGKLAKAIIHNRPIQSATQLAEIAQKILPKNKRVHPATTLFQAIRIEVNKELDQLKGLLDALERHKPKGAKVAIITFHSLEDRIVKQHFKEWAKSCICPPEAMRCTCGANHALGNIVTKKPIVASIDELEENPRARSAKLRVFQFKE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAS1_SYNY3
Sequence: MDTAVNESLSISYNLEQFLIVLSVSLSIATLSKTVPILRKIPYTLLLVIVGMALAFVDVKLINLSPELIMEIFLPPLLFEAAWNLQWRNLKENWFPITLFATLGVVICVVGIAFPLSYWGGMELAIAFLAAAALSATDPVSVIALFKELGASKKLNTLMEGESLFNDGVAVVVFLILVGIPLGTSTFDLSVTLARFVTVIGIGVGCGLVIGFSLSLLTQRFDLPFVEQSLTLVSAYGAYILAENLGGSGVIGVVVVGMVLGNYGSRIGMNPRTRLIVSIFWEFVAFFVNSIIFLLIGDQIGLSSLSDHLNLILIAIAAVVVTRLVSVFGLSLISNKVSDQISSTHITLQEQTVLWWGGLRGSVAIAVALSVPQAIAERQAIIDIVFGVVLFTLLVQGLTTQFVLKGLDLIGDQPQRLEYAELVSRQIALRRVLAELEKTDEFPDINPERLRYKQELVQGQLQSVTDKLKLLLQEYPLLQEVANKKFDQTVLDIEAETYADLIRMGRLEENIMPLLVTLEGENVAEPS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.  Might be able to function at relatively high concentrations of Na(+) ions.  Has also Li(+)/H(+) antiport activity under K(+)-rich conditions, but it might not have any physiological relevance.
What are the official names of this protein?
Low-affinity Na(+)/H(+) antiporter NhaS1, Sodium/proton antiporter NhaS1.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_DEIRA
Sequence: MAKPTKGKAPRRSRRNISAGRAYVHASYNNTIVTITDLDGNSVAWSSGGTIGYKGSKKGTPYAAQLAAADAVKKAQTSFGMAAVDVIVRGSGSGREQAIRAIQASGIEVRSIMDDSPVPHNGCRPKKKFRA
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: IRC6_PICGU
Sequence: MAQNNVLVLGAPHSGKLRASAIIGAGFSGDGDFSGSHSGLIFKIKRQTKYFKHDLSIMVDEYPEKRTITPSWEHLNAWSDEFMSEDMEELRRALDGIVFCLNLDDKATMKDLEPTIGVLEKIYESLGGAEWAGFFAIVGVSSSEDNENHAIVEDAATIRGFEYINLEEEGQNEFRDKLGIDRLVELFDTHDWSDIETSEDDGFAARKRKMAESMCQRLLDDDEKDMSSENGVNDVNVEEFENVIEKLKQARIKAESMEGAERNEYAQQVMEDVLSYL
What is the function of this protein?
Involved in gross chromosomal rearrangements (GCRs) and telomere healing.
What are the official names of this protein?
Increased recombination centers protein 6.
What is the protein family that this protein belongs to?
Belongs to the IRC6 family.
Protein: RPOB_PEDPA
Sequence: MAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQSDSYQWFLDEGLREMFNDIMPIEDFAGKLSLEFVDYQLLEPKYTVDEAREHEANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYNLDTDKNNRKIWGTTVIPNRGAWLEYETDAKEISYVRIDRTRKIPMTELVRALGFGSDEEIIDIFGGSDSLDFTLDKDVHKNPEDSRVAESLKDIYERLRPGEPKTADSSRSLLTARFFDPKRYDMAPVGRYKVNKKLSLKTRLLGQTLAETLADPDTGEVIAQKGEMVNKDVMKKLAVFLDRPDFKMVTYQPSEEAVVTEPMTIQVIKVQDPNDPERTLNMIGNGNIDAKLKHITPADIIASMNYFFLLQDGIGSTDDIDHLGNRRIRSVGELLQNQFRIGLSRMERVVRERMSIQDAETVTPQQLINIRPVVAATKEFFGSSQLSQFMDQTNPLGELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLASYGKINRYGFIETPYRRVSWEDHKVTDRIDYLTADEEDQFVIAQANSPLNDDGSFADDVVMARHESDNIETSIENVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLVDPHSPLIGTGIEYKAAHDSGVALLCQHAGVVEYVDAREVRVRRDDGALDTYKLMKFRRSNGGKNYNQRPIVRVNDKVDADEVLADGPSMEQGELALGQNPLIAFMTWQGYNFEDAIAINERLVRDDVYTSIHIEEYESEARDTKLGPEEMTREIPNIGEDALRNLDQDGIVRVGAEVEDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGGGGIVQDVKIFTRENGDELSPGVNMMVRVYIAQKRKLQVGDKMAGRHGNKGTVSVVIPQEDMPYMPDGTPIDIMLSPMGVPSRMNIGQVLELHLGMAARNLGIHMTTPVFDGAQDKDIWEAVAEAGMDSDAKSVLYDGRTGEPFEQRVAVGVMHYMKLAHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPRPGVPESFRVLVKELQALGLDMKVLGGDDQEVELRDMDEEDDDVVNVDALSKYAEKQNEKTNASAEEAKAPSTESAPVETKNNQN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NUSB_YERPG
Sequence: MKPAARRRARECAVQALYSWQLSKNDIADVELQFLSEQDVKDVDIAYFRELLSGVAVNAASLDALMAPFLSRQLEELGQVERAVLRIALFELSKRDDVPYKVAINEAIELAKTFGAEDSHKFVNGVLDKVAPTVRKRK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MSRB_BRUME
Sequence: MKYQKSAEAIAKLSAEQYRVTQENGTERPGTGEYLYNKEPGIYVDIVSGEPLFASSDKYESHCGWPSFTKPIERANVTELTDMSHGMVRTEVRSAHGDSHLGHVFPDGPVDRGGLRYCINSASLRFVPKDRMEAEGYGDYLDQVEG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: LPTD_ECOK1
Sequence: MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYKDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLAESANRVMPQFKVDGRMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSKIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISDRWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: MSRB_ECOL5
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: MTLD_YERE8
Sequence: MKALHFGAGNIGRGFIGKLLADAGAQLTFADVNQPLLDELNKRKSYQVNVVGEQARVEEVKNVSAVNSGSPEVVELIAQADMVTTAVGPQILARIAGTVAQGLVTRHQQGNTRPLNIIACENMVRGTSQLKQQVFAALPESEQAWVEQHVGFVDSAVDRIVPPSEAGSTDILAVTVETFSEWIVDGTQFKGQPPQIAGMELTDNLMAFVERKLFTLNTGHAITAYLGQLAGHQTIRDAILDPAVRQTVKGAMEESGAVLIKRYAFDPLKHAAYIEKILSRFENPYLHDDVERVGRQPLRKLSAGDRLIKPLLGTLEYQLPHNNLVTGIAAAMSYRSEQDPQAQELVELLAKLGPKATLAQISGLPADSEVVEQAVSVYNAMQDKLAH
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: PLSX_LISMC
Sequence: MKIAVDAMGGDHAPKEIVLGVMKAVAQYKDVEILLFGDETKINEYLTDKTRVKIIHTDEKIESDDEPVRAVKRKKKASMVLAAQAVKDGEADACISAGNTGALMSTGLFVIGRIKGIDRPALAPTLPTVTGKGFVMLDLGANAEAKPEHLLQFGLMGSVYAEKVRKIDRPRVALLNIGTEETKGNDLTKKSFELMKNQDAYEFIGNIEARDLLMDVADVVVTDGFTGNMVLKSIEGTGAAFLSMLKMSLLNGFKNKVAASFLKKDLMALKAKMDYSEYGGACLFGVQAPVVKAHGSSNANGIFTTIRQVREMVEKQVVETIKAEVDKVKVGGTESND
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: REV_HV1A2
Sequence: MAGRSGDSDEELLRTVRLIKLLYQSNPPPSPEGTRQARRNRRRRWRERQRQIRSISGWILSTYLGRSAEPVPLQLPPLERLTLDCSEDCGNSGAQGVGSPQILVESPAVLDSGTKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: OXDD2_CAEEL
Sequence: MANIIPKIAIIGEGVIGCTSALQISKAIPNAKITVLHDKPFKKSCSAGPAGLFRIDYEENTEYGRASFAWFSHLYRTTKGSETGVKLVSGHIQSDNLESLKQQQRAYGDIVYNFRFLDDRERLDIFPEPSKHCIHYTAYASEGNKYVPYLKNLLLEQKIEFKQQEVTSLDAVADAGYDVIVNCAGLYGGKLAGDDDTCYPIRGVILEVDAPWHKHFNYRDFTTFTIPKEHSVVVGSTKQDNRWDLEITDEDRNDILKRYIALHPGMREPKIIKEWSALRPGRKHVRIEAQKRTSVGNSKDYMVVHHYGHGSNGFTLGWGTAIEATKLVKTALGL
What is the function of this protein?
Selectively catalyzes the oxidative deamination of D-aspartate and its N-methylated derivative, N-methyl D-aspartate.  Highest catalytic efficiency for D-Glu followed by D-Asp and NMDA.  May play a role in the egg-laying events and early development of the worm, in addition to quality control of the germ cells.
What are the official names of this protein?
D-aspartate oxidase 2, DASOX 2, DDO-2.
What is the protein family that this protein belongs to?
Belongs to the DAMOX/DASOX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y346_CHLPN
Sequence: MALGPSPYYGVSFFQFFSVFFSRLFSGSLFTGSLYIDDIQIIVFLAISCSGAFAGTFLVLRKMAMYANAVSHTVLFGLVCVCLFTHQLTTLSLGTLTLAAMATAMLTGFLIYFIRNTFKVSEESSTALVFSLLFSLSLVLLVFMTKNAHIGTELVLGNADSLTKEDIFPVTIVILANAVITIFAFRSLVCSSFDSVFASSLGIPIRLVDYLIIFQLSACLVGAFKAVGVLMALAFLIIPSLIAKVIAKSIRSLMAWSLVFSIGTAFLAPASSRAILSAYDLGLSTSGISVVFLTMMYIVVKFISYFRGYFSKNFEKISEKSSQY
What is the function of this protein?
Part of an ATP-driven transport system CPn_0346/CPn_0347/CPn_0348/CPn_0349 for a metal.
What are the official names of this protein?
Probable metal transport system membrane protein CPn_0346/CP_0414/CPj0346/CpB0353.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYOD_BUCAI
Sequence: MSSFLNFNMNKEMKSYLLGFLFSSLLTTLPFLLAIEKFFCSEVNYIIFLLCAISQIIIHFVYFLHLSFDPEERWNLITLLFVIIIIFIVVFGSIWIMFNLNHNTM
What is the function of this protein?
Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration.  Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity).
What are the official names of this protein?
Cytochrome bo(3) ubiquinol oxidase subunit 4, Cytochrome o ubiquinol oxidase subunit 4, Cytochrome o subunit 4, Oxidase bo(3) subunit 4, Ubiquinol oxidase polypeptide IV, Ubiquinol oxidase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURA_SYMTH
Sequence: MPVVVVMGAQWGDEGKGKFVDLLAERAQVVVRSTGGSNAGHTVWAGGRQYKLHQVPSGILYPGTLCVIGHGVVLDPPKLLEEMDRLASQGVDLSSLRISGGAHIVFPFHIRLDEAEEDRKGDRKIGTTRRGIGPAYMDKFARVGIRLVDMLDRDEFLPKLTALVEEKNRILEKVYGLPGFTVEEIAEPYLEYAERLRPYVANTVELVNDAIDAGKNVLFEGAQGHLLDIDFGTYPYVTASHPIAAGAIIGAGVGPTKVSRVVGVVKAYTSRVGEGPFPTELHGEEAHRIREEGHEYGTTTGRPRRIGWLDLVMVRYACRVSGITDLAVPHLDTLAKTGLPTLKVCVGYRMPDGTVTREFPVGLKALSQVEPVYEELPNWEWSAEMSTARQYDELPEGARRYVRLIEDVTGVRVSILGVGSERTQAIYRSAIF
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_BDEBA
Sequence: MFSKLDAVESRYEEVNMALQRPDIASNQTQYRALMKELGNLEKIVLVYRDYRKKTENLKASKELLTAEQDAEMRELIREEVKELEAELPDLEQQLKIALIPKDPNDDKNTILEIRAGAGGDEAALFADELFRGYVHYASTQGWKVEMISFSEGNAGGAKEIIASITGDSVFSKMKYESGVHRVQRVPKTEAAGRIHTSTVTVAVIPEVEVSEIKIPMSDVRIETMRSQGSGGQSVNRTESAVRVVHLPTGIDVKCQEGKSQSTNRERAFQILYAKLQQIEDEKARKEASDVRLEQIGTGDRSERIRTYNFPQTRITDHRIGLTIHQLDQVMSGSFELLIDPLIANFQAEALKKQVSA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_NITEC
Sequence: MTRAGFVAGNWKMYGNLVQNQELLAAIVLGIPSLQNASCAVCVPYPYLAQAQSVLKGTHVAWGGQNISQHHQGAYTGEVSAGMLTDFGCRYVIVGHSERRTLYGEDNQMVAEKFHSAQEQSLVPILCVGETLAQREANETEQVIARQLDAVIGLVGVNAIKQSVIAYEPVWAIGTGETATPQQAQDVHAFVRNRIAAHNSEIAADIQIVYGGSVKANNASELFAMPDIDGGLIGGASLVAAEFISICFAAQS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_DESAP
Sequence: MGRSLKKGPYCSPKLLARIEEMNEKDQKRVVKTWSRRSTIFPQMIGHTIAVYDGRKHVPVYVTEEMVGHKLGEFAPTRTYRGHGHHTERSTALK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SOXR_ECOLI
Sequence: MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSGNQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVLPEGHTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN
What is the function of this protein?
Activates the transcription of the soxS gene which itself controls the superoxide response regulon.  SoxR contains a 2Fe-2S iron-sulfur cluster that may act as a redox sensor system that recognizes superoxide.  The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress.  Upon reduction of 2Fe-2S cluster, SoxR reversibly loses its transcriptional activity, but retains its DNA binding affinity.
What are the official names of this protein?
Redox-sensitive transcriptional activator SoxR.
Protein: RS19_VARPS
Sequence: MTRSLKKGPFVDHHLVAKADKAVTTKDKKPIKTWSRRSMVLPEFIGLTIAVHNGKQHVPVYITDQMVGHKLGEFALTRTFKGHPADKKVQKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.