PharMolix/UniProtQA huggingface dataset:
Protein: SPLD_STAA3
Sequence: MNKNIIIKSIAALTILTSITGVGTTVVDGIQQTAKAENSVKLITNTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVTSDAVVQPGSSGSPILNSKREAIGVMYASDKPTGESTRSFAVYFSPEIKKFIADNLDK
What are the official names of this protein?
Serine protease SplD.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_ZEUFA
Sequence: MASLRKTHPLLKIVNDALIDLPAPANISVWWNFGSLLGLCLLTQILTGLFLAMHYTSDIATAFSSVAHICRDVNYGWLIRNFHANGASFFFICLYLHIGRGLYYGSYLYKETWNVGVVLFLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGDILVQWIWGGFSVDNATLTRFFAFHFLFPFIIAAMTILHFLFLHETGSNNPAGLNSDADKVSFHPYFSYKDLLGFVVMLLALSTLSLFSPNLLGDPDNFIPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLSSILILMLVPILHTSKQRGLTFRPLTQILFWVLVADVAILTWIGGMPVEHPFIIVGQVASVLYFALFLVIMPTTGWMENKALKWN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLRA3_HUMAN
Sequence: MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
What is the function of this protein?
Glycine receptors are ligand-gated chloride channels.  Channel opening is triggered by extracellular glycine (PubMed:9677400, PubMed:26416729).  Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure (By similarity).  Plays an important role in the down-regulation of neuronal excitability (By similarity).  Contributes to the generation of inhibitory postsynaptic currents (By similarity).  Contributes to increased pain perception in response to increased prostaglandin E2 levels (By similarity).  Plays a role in cellular responses to ethanol (By similarity).
What are the official names of this protein?
Glycine receptor subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Synapse. Cell membrane; Multi-pass membrane protein. Note=Partially colocalizes with GPHN that is known to mediate receptor clustering at postsynaptic membranes.
Protein: OTAC_ASPC5
Sequence: MNMDSIASFSHPFLWTAFAVGVVYCCTRMVSELFLSPLSHIPGPKLAACTRLYEFFYDVICHGRYTFKIAELHEKYGPIVRISPTEIHINDPEFYETLYSTSAPRNKDPWFTTNFDVAESAFSTLDYRLHRPRRALIAPYFAKARVDRIQPLIQGKITKLMRQLDEYARAGKPLKVDVAYNCFTADVITGYTSYRPLGYLDTPDMVPIWSETVRNLVEIGMIARHLPGFFPLLASTGARCIQMVYPKLLSVIAFRVKCIQEVNFMWTHPETATKDAAQAECSEPALFPELVSRASTTPDITEERVLHEFITIVAAGTETTAHTMTVCTFHILNNKDILRRLRAELNDKFPGDATMDLQTLEQLPYLTGIIYEGLRLSYGLSHRLQRISPTDPLKYKDVVIPPNTPVGMSSALIHHDETIFPQSHAFIPDRWTDINERRRLNKYMVAFSKGSRQCIGMNLAFAELYMAVAALFRKYDMELQDTTVDDVKLHSDMMLPHAKKGSKGVRVILKPAQGGE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of ochratoxin A (OTA), a mycotoxin composed of a chlorinated type I polyketide dihydroisocoumarin moiety linked to L-phenylalanine, and demonstrated to have nephrotoxic, immunotoxic, genotoxic, neurotoxic, and teratogenic properties (PubMed:30054361).  OtaC catalyzes the oxidation of 7-methylmellein (7-MM) into 7-carboxymellein (PubMed:30054361).  The pathway begins with the highly reducing polyketide synthase otaA that catalyzes the formation of the isocoumarin group during the initial stages of biosynthesis, starting from one acetate and 4 malonate units, to originate the characteristic pentaketide skeleton 7-methylmellein (7-MM) of the OTA molecule.  The newly identified cyclase otaY might be involved in the polyketide cyclization reaction during the initial steps of the OTA biosynthesis.  7-MM is then oxidized into 7-carboxymellein (also called ochratoxin beta) by the cytochrome P450 monooxygenase otaC.  The NRPS encoded by the otaB gene is involved in the linking of phenylalanine to the dihydroisocoumarin ring.  The reaction catalyzed by NRPS results in the production of ochratoxin B (OTB), which is the non-chlorinated analog of OTA and which subsequently serves as the substrate of the halogenase otaD for chlorination activity to form the final molecular structure of OTA, containing a chlorine atom in the C-5 position of the molecule (PubMed:33391201) (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase otaC, Ochratoxin A biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: COX16_CAEEL
Sequence: MSRLKFVRVGLPFFAIVLGSAYGLHFFQQVRFDFRKIKQEDDNLELLRSDLTRSGLRLREGVTVESVYKEVAELDTDNWENIRGPRDTEDLTDYNLIKKQQQEASRKVRELKSNV
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RNH2_THEPD
Sequence: MGRVAGIDEAGRGPMLGPMVVAIVVCPEEKVPLLRNMGVRDSKALSPRRRLLLSRAIPSVGCSVKVRVVEPQEIDCAVRGECYENLNHLEAAVFAQLINEVLSEGELEVVYMDSPDPVPSRFEERVRALLKGQVRIVAENGADEKYTIVGAASIVAKETRDEIINALKKTYGDFGSGYPSDPRTLRFAEEWVRKHGEPPPIARKEWATWKRLR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INCE_CHLTR
Sequence: MECVKQLCRNHLCLDSLTGPVRSVLTQGTTAEKVQLVVSCLGVVCSIICLALGIAAAAVGVSCSGFAIGLGVIAILLGIVLFAISALDVLEDHGLVGCPFKLPCKSSPANEPTVQFFKGKNGSADKVILVTQ
What is the function of this protein?
Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion.
What are the official names of this protein?
Inclusion membrane protein E.
What are the subcellular locations of this protein?
Secreted. Host vacuole, host pathogen-containing vacuole, host pathogen-containing vacuole membrane; Multi-pass membrane protein. Note=Secreted, probably by a type III secretion system (By similarity). Localized in the inclusion membrane (By similarity).
Protein: Y1493_STRP1
Sequence: MGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSDNDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTIEASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTELYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLDSYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAFAVMVRYE
What is the function of this protein?
Binds long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein SPy_1493/M5005_Spy1226.
Protein: EIF3F_ASPTN
Sequence: MAAADPFLHLARPLGPVAVGSAPTTAPLNVVIQPQALFSILDHSLRRNADQERVIGTLLGTRSEDGTEVEIRSTFAVGHTETTDQVEVDMEYQKQMLALHLKANPKEVLVGWYATSSELNTFSALIQNFYSGQGDGTFPHPAVHLTVSTEPGKDIETRAYISAPVGVTAERAADSAAFIPVPHEIRYGETEKSGLEAIAAARDAEERAANLFTDIEALERAIEEVLGMIDRVSRYVESVIDEEAPASTALGQFLLNALALAPKVEPADIERDFNNHIQDVLVVSYLANTIRTQMELSNRLATAQLTLGGESGSTESGQRGGQRGGKGGRGGQQRNQERSGEEVRA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_STAAR
Sequence: MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFATLDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFEYVKGRPFADNFAKSVDKWRELYSNDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAIHGKFVDVRKVVV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: HIS1_SORC5
Sequence: MTKPLTIAVPKGRILKDLIPLVRRAGLDSTPLEENDRRLVRPTADGAFRYVFLKPDDVPTYVEYGAADLGVSGRDTLLERRHDLYTPLDLGIGRCRLVVAGPEDTEVPDLPRVATKYPRIAGDHFASKGVVAEIIPVHGSVELAPLVGLSHLIVDIVETGSTLRENRLEVLETVTEVSTQLIANRASYKLRSDVIRPLVERLRAATAGAGR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL333_STAAE
Sequence: MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DNAK_ANAMM
Sequence: MGVIMAAERIIGIDLGTTNSCVAVMEAGTAKVIENSEGSRTTPSVVAFTENERLVGELAKRQANINAQNTIYASKRIIGRRYDDMRDVKCPYEVFPAKNGDAWIRARGEGYSPVQIGAFVLEKIKETAERYFGAPVKKAVITVPAYFNDAQRQATKDAGTIAGLDVVRIINEPTAAALAYGLDKGDKQRTIVVYDLGGGTFDVSVLEIAEGVFEVKATNGDTKLGGEDFDNAVMEHMMESFKQETGIDLHNDPMAVQRIKEAAEKAKIELSSRLETDITLPFISSDSTGAKHLSLKLTRAKFEGLVSELIERTIEPCKKALDDAGIKDTSKIDEVVLVGGMTRMPKVIQRVKDFFGGKEPCKGVNPDEVVAIGAAIQGGILTGDVRDVLLLDVAPLSLGIETLGGVFTPLIERNTTIPTKKSQVFSTAEDGQTAVTIKVYQGERKMAVDNKLLGQFSLEGIPSAPRGIPQIEVTFDIDANGIVHVSAKDKASGKEQTIKIQSSGGLSEEEIKKMVQDAQDRAEEDEKRKKRVELKNSAEALIHSTEKSLNDYGDKISSADKSGIEAAIKELRECLSNDDSSSDVIQQKYDALMQLSMKLGEAAYSAQKDSGTSTDSTASDTSGNPEERVVDSEYQEIKKDDEDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PARE_MYCGA
Sequence: MVSNYNEKHIKVLKGLEPVRKRPGMYIGSTDTRGLHHLVWELFDNAVDEALNGSANKIEVVHKKDGSIIVTDNGRGIPVGKNLATNLSTVDTVYTVLHAGGKFDDQAYKVSGGLHGVGASVVNALSRKLIVTVHRDGGMYESIYQDGGKIIQPLKKVGNSTKHGTIVQFWPDPTIFKNIQFNPYMIKERLHESSFLFKGLKIVFVDENNPELSQTFIAKDGILEYLKYVNENKKSISKIIPFKGDYEKIVVDGCFQYTDNESELIISFANSVKTSEGGSHENGFKQAMLETINDYSKKYKLINNKDKGFDWSDLKEGLSVVLSVQVPEKIIAYEGQTKNKLFTQEVKVAVAKILTQQLFYFLEENQADAKQLIERFKLIKEAKEAAKKAKENTKKLKSAKSERVLYGKLTPAQQKNPLQNEIFLVEGDSAGGTAKSGRDKRFQAILPLRGKVVNVEKSRLQDLLKNEEILSIISCLGCGIGNNFNIKNLKYHKIIIMTDADTDGAHIQVLLLTFFYRYMKELIEQGKVYIALAPLYKISAKNSNKSAFAWDDYQLDELRTKYGSYEVQRYKGLGEMNSEQLWTTTMDPSKRQLIQVSIQNAAQAERKVSILMGDDASIRKNWINENVDFSIEE
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit B, Topoisomerase IV subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family. ParE type 2 subfamily.
Protein: MOBB_BACSU
Sequence: MALVRPFPIVQVVGFQNSGKTTFIERILEKASEQGVHLGCLKHHGHGGEPQTLTEGKDTDRYKAAGADVTAVEGAGVLQLTARRNWDLARLIELYQFLETDCLLIEGFKKAPYPKVVILSEKEDLEALQAVNIIAIIYRKKEHMTEHQGLPVFHADDPVAVDFVLSQLKGESA
What is the function of this protein?
GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor.  May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD.  Displays a weak intrinsic GTPase activity (By similarity).
What are the official names of this protein?
Probable molybdopterin-guanine dinucleotide biosynthesis adapter protein, MGD biosynthesis adapter protein, Molybdenum cofactor biosynthesis adapter protein, Moco biosynthesis adapter protein.
What is the protein family that this protein belongs to?
Belongs to the MobB family.
Protein: RL20_GEOSW
Sequence: MPRVKGGTVTRRRRKKVLKLAKGYFGAKHALYRVANQQVMKSLMYAYRDRRQRKRDFRKLWIARINAAARMHGLSYSRFMHGLKLAGVEVNRKMLADLAVNDQAAFAQLADLAKANLNK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: HOP1_SCHPO
Sequence: MNSYKEEILQTKSDFTLKNLIFFAISTLCYKRALFNENCYKKVNFEIEHFKGADFDCQLKPTVVSLQAGVDKEADSFLEMMKTYIFSLVSMKVPFTVYLIISSQCKSILEDDAVEKEIFSFTINPGSEEKICCESFVSYQRSERFVIKLFLSGNVKTECKDEEKVVQIITKMERFQLSKGEATKAGVFLNTVETKDCMSWLNRGEFKDIVSFYESNNGIAISHCSHAFVPISTEKIMINKESSLFDSQEKIDSQLEKFLQPLKYDEIGSTQILDEQSVEKSLSQGKCEKMQNESRGLREIKNNNPCEEVKKSNWLKKNISGSDKVDKAEKKKALLNCECGDSTEDSEMFQCERCDGWVHCACYGFESDSDPRQPNQLLCYTCLLVDSESSLYDRMTMLVAYRRAIRCIWASEYQGFQKLAARLNCSYADAKRIEERLVNENIIYKEKKRKWIYFTNKSPEMVSYLREKYFTPSRWISHLNFQNYRQENQRVNMRSFLRPERMEVIERPKKVSKTSNTKETDTMKPLRI
What is the function of this protein?
Facilitates initiation of meiotic recombination and DNA double-strand break (DSB) formation at DSB hotspot sites by enhancing the interaction between rec10 and rec15.
What are the official names of this protein?
Linear element-associated protein hop1, Meiosis-specific protein hop1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Predominantly localizes to linear elements (LinEs) on meiotic chromosomes, the S.pombe equivalents of synaptonemal complexes. A proportion also localizes to DNA double-strand break (DSB) hotspots.
Protein: DLDH_CHLP8
Sequence: MQQSESSSAQFDVAVIGSGPGGYEAALHAARHGMKVCLVEKASLGGVCVNWGCIPTKALLRSAEVYDLAKNPSEFGVNVSELSFDLAQAVKRSRKVSLKSSKGVEFMLKKAKVEVWRGEAVLTGSKGVKVTAEDGSERSLEAANIIVATGAQPRVIPGLEPDGKKIITSREALILKDVPESMIVVGGGAIGVEMAWFYAKAGAKVTIVELMPRLLPAEEAEVSEALKRSFEKVDITVQCGAKLGNVAISEFGVNADLLAEGKEPQKIEASCMLVAVGVTGVIDGLGLDAAGIETERGFIRTDELCRTSASGIYAIGDVRGGMLLAHKASAEAAIAVEAIAGKLPEPLSEPLIPRCVYAQPSVASVGLTEEAAIAAGYKVLVGRSQFAASGKANAYGQLEGFVKLVFNAETGKMLGGHLIGHDAVELIGELGLACRYGVTAEGLVGTVHAHPTLSETVREAAFAALQSKG
What is the function of this protein?
Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_BACMK
Sequence: MTNVTGTERVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGAAMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLLEIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSENPEKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: ARGJ_KLULA
Sequence: MKVTFSLMQKASKQIDKFALYVPKSGVFPKGFKVATQATGVKKNGNLDLGIIRNVNTSRPSSAAAVFTTNKFKAAPVLVSKEVLEVTGGENVDAIVVNSGCANAVTGEVGLKDAREIAGVANQNLGKQNATLVMSTGVIGQRLSMDKIVPALSQQFETNAFKDDFESWLNLARAISTTDTFPKLISSNFKLANGTEYTLTGIAKGAGMICPNMATLLGFIVTDLPITPSALQKMLRSATDRSFNCISVDGDMSTNDTISMLANGAVDTAVIDENSQDFVQVQTQVTEFAQRLAQLVVRDGEGSTKFVTVNVKNALNFKDAKIIAESISNSMLVKTALYGQDANWGRILCAIGYAKLDNLQSLDDKKINVSFVATDNSEPKELKLIVDGVPQLDIDEARASELLAQQDLEVLVDLGTGSEECQFWTCDLTHEYVTINGDYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FOLD_PHOLL
Sequence: MPAKIIDGKTIAQTIRSEVAVRVQQRVAAGRRAPGLAVVLVGENPASQIYVASKRRACEEVGFVSRSYDLPDTTSEAELLNLIDQLNNDSDIDGILVQLPLPAGIDNVKVLERIQPDKDVDGFHPYNIGRLCQRAPKLRPCTPRGIATLLERCGINTYGLNAVIIGASNIVGRPMSLELLLAGCTTTVTHRFTKDLRHHVEQADLLIVAVGKPNFIPGEWIKPGAIVIDVGINRLEDGKVIGDVDFETASERASWISPVPGGVGPMTVATLIQNTLQACEEYHDVERIEGC
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HCY5_MAJSQ
Sequence: DHAGTVSKAHKQHDVNSVLYKVYEDI
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin subunit 5.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: YIPF3_RAT
Sequence: MATQAAPASGVRNGAGPEWGGFEENIQGGGSAVIDMENMDDTSGSSFEDMGELHQRLREEEVDADAAAAEEEDGEFLGMKGFKGQLSRQVADQMWQAGKRQASKAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKMVNFPQKVAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHLHALFYLFWLLLGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLEGPNIPPMQRVPRDIPAVLPAAKLPVAVVNATAKAIAVTLQSH
What is the function of this protein?
Involved in the maintenance of the Golgi structure.  May play a role in hematopoiesis (By similarity).
What are the official names of this protein?
Protein YIPF3, Liver regeneration-related protein LRRGT00110, YIP1 family member 3.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Cytoplasm.
Protein: EPCAM_MACMU
Sequence: MAPPQVLAFGLLLAAATASFAAAQKECVCENYKLAVNCFLNDNGQCQCTSIGAQNTVLCSKLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTSTCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDVQSLRTALEEAIKTRYQLDPKFITNILYEDNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLRVNGEQLDLDPGQTLIYYVDEKAPEFSMQGLKAGVIAVIVVVVIAIVAGIVVLVISRKKRMAKYEKAEIKEMGEIHRELNA
What is the function of this protein?
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection.  Plays a role in embryonic stem cells proliferation and differentiation.  Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
What are the official names of this protein?
Epithelial cell adhesion molecule, Ep-CAM, Tumor-associated calcium signal transducer 1.
What is the protein family that this protein belongs to?
Belongs to the EPCAM family.
What are the subcellular locations of this protein?
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction.
Protein: PIP15_ARATH
Sequence: MEGKEEDVNVGANKFPERQPIGTAAQTESKDYKEPPPAPFFEPGELKSWSFYRAGIAEFIATFLFLYVTVLTVMGVKRAPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRALFYIVMQCLGAICGAGVVKGFQPGLYQTNGGGANVVAHGYTKGSGLGAEIVGTFVLVYTVFSATDAKRSARDSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKDHAWDDHWIFWVGPFIGAALAALYHQIVIRAIPFKSKT
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Probable aquaporin PIP1-5, AtPIP1;5, Plasma membrane intrinsic protein 1d, PIP1d.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAX92_MESMA
Sequence: MSRLFTLVLIVLAMNVMMAIISDPVVEAVGCEECPMHCKGKNANPTCDDGVCNCNV
What is the function of this protein?
Blocks small conductance calcium-activated potassium channels (KCNN, SK).  Low toxicity by intracerebroventricular injection into mice.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 9.2, Neurotoxin BmP03.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 09 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_THEP3
Sequence: MARVKFGKVTRRRRKKILKLAKGYFGAKSKLFRVANQAVMKSLMYAYIGRKLRKRDFRKLWITRINAAARAHGISYSRFINGLKKAGIEINRKMLSEMAINDEKAFAELVNIAKQQLNA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.