PharMolix/UniProtQA huggingface dataset:
Protein: Y207_BRUME
Sequence: MTELASPTSFSMPDIGKSPVVLTARRLMRHRSFRIGLVLLLIVVLAAVLAPWITNGKPNATSVRMRFQPPGLEHLFGTDNFGRDLWTRVLYGAQVSLWIGLTVAVLSAILGAIIGIAAAWYRRFDTLLMRVMDALMAFPAILLAIGISAALGPHLSSVIIALTSAYIPRCARIVRASALVLRETDYVDAARLAGASDLRIITRHILPNCLAPLLVTLTFVFAYAILAEATLSFLGIGTPPPHASWGSIVAQGRDYSVDAWWIMLFPGIAITISALAINLIGDGLRDVLDPRLKMEG
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Putative peptide transport system permease protein BMEII0207/BMEII0208.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NS3_BCHK9
Sequence: MNLYNLVRDALRPSYATVSPSVDEPTVDNNFVALSCYATLSVLLYYLQRVKQPYLSMLFHILFCLSQVCMVIWLIFSANFYVSLFAQCMLVVCALGCFLERTILSIKLRSMAPFMSMADNFAIIKTTCNNYVFPVERSSDNLVVLTTSRGIYSNGVFMKGAITVSDNALVVSLFKSHSLLLDRVEHGYDYTVFIYINSVILQNIKPTVSVVNTEFTDVEL
What are the official names of this protein?
Non-structural protein 3, ns3, Accessory protein 3.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: PNP_ANAPZ
Sequence: MFDITRKCVEWGDRSLTIESGKIARQAGGAVVVDYGGTSVLATVVSQKSKEAVDFLPLTVQFLAKSYAVGKIPGGFFKREGKPSDRETLISRIIDRSIRPLFPSGFSDEVAVVCNLLSYDASSPPETVALIGASAALAISGIPFHCPVAGARIGYIRGEGRYILNPSADELSVSALDMFYARTDTSILMVESEAHELTEAEMLGALQFGHEHCEEIIKVIGEFAEEARKCAPAEFVPCDLSTIIDSIGSDYKERFLVAYSEKEKKARVAKLDAVRASLTEDLRVKFLSESEGGSKYIAQDIVYAMKTFERSLVRERVLESKSRIDGRAYDQIRNIEIEVDLISKAHGSALFTRGDTQALVITALGTPQDEQIVDGFDGDKRERFLLHYNFPPYAVGEASALRPPGRREIGHGKLAWRAIHPVLPSKADFPYTIRVVSEITESDGSSSMATVCGASLALMDTGVPLKSSVAGIAMGLIKEGDRYAILSDILGDEDYLGDMDFKVAGTREGITALQMDMKVKGIDFAVLGTALDQAKEGRFFIIEKMDRVIKESRGAVREHVPRMESMLIDKGKIKNVIGAGGKNVREICEKTGAKIEISQDGTVMIYAVGREAIESAKDMITGIVSEPEVGKIYSGEVCELAKYGAFVTFLGARKGLVHISEIRNEHINAVADVLAVGDKVKVLVIDMDKDHIQLSMRRIDQETGDQVDCELYAPQRRNGVAAGNTVGDSSVNGGGAGSVYVPRGDYGGASAGRNGRGGGKRDGAAKSSSSAGNGGGRSSSSTRRRHSAGSSGYSSDSSSGNTKSSSSESSGGTGGRGRNGANGDVQNGPAAPKKPRFF
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5058_PSEE4
Sequence: MKTFAPSYLKHQFLIAMPHMADPNFAHTLTYIVEHNANGAMGLVINRPQELNLADILEQLRPNEQPPASTLQVPIYQGGPVQTDRGFVLHSDECSFQATVALEGLSLTTSQDVLLAIAAGVGPKKSLITLGYAGWEAGQLEAELADNAWLNCPFDPEIIFGLASDQRLGAAAASLGINLSLLTSQAGHA
What are the official names of this protein?
UPF0301 protein PSEEN5058.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: COA1_HUMAN
Sequence: MMWQKYAGSRRSMPLGARILFHGVFYAGGFAIVYYLIQKFHSRALYYKLAVEQLQSHPEAQEALGPPLNIHYLKLIDRENFVDIVDAKLKIPVSGSKSEGLLYVHSSRGGPFQRWHLDEVFLELKDGQQIPVFKLSGENGDEVKKE
What is the function of this protein?
Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.  MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion.  Required for assembly of mitochondrial respiratory chain complex I and complex IV (PubMed:23260140).  As part of the MCIA complex, required for efficient assembly of the mitochondrial complex I (PubMed:32320651).
What are the official names of this protein?
Cytochrome c oxidase assembly factor 1 homolog, Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa.
What is the protein family that this protein belongs to?
Belongs to the COA1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PRDM6_MOUSE
Sequence: MLKPGDPGGSAFLKVDPAYLQHWQQLFPHGGGGGGPLKASGAALALGAPQPLQPPPPPPPPPPERAEPPPDGLRPRPASLSSTPAPSSTSASSASSCAAAAAAAALAGLSALPVAQMPVFAPLAAAAVAAEPLPPKDLCLGASAGPGPAKCGGGGGSVGDGRGVPRFRCSAEELDYYLYGQQRMEIIPLNQHTSDPNNRCDMCADNRNGECPMHGPLHSLRRLVGTSSAAAAAPPPELPEWLRDLPREVCLCTSTVPGLAYGICAAQRIQQGTWIGPFQGVLLSPEKVQTGVVRNTQHLWEIYDQDGTLQHFIDGGEPSKSSWMRYIRCARHCGEQNLTVVQYRSNIFYRACIDIPRGTELLVWYNDSYTSFFGIPLQCIAQDENLNVPSTVMEAMCRQDALQPFNKSSKLSPSGQQRSVVFPQTPCSRNFSLLDKSGPMEAGFNQINVKNQRVLASPTSTSQLHSEFSDWHLWKCGQCFKTFTQRILLQMHVCTQNPDRPYQCGHCSQSFSQPSELRNHVVTHSSDRPFKCGYCGRAFAGATTLNNHIRTHTGEKPFKCERCERSFTQATQLSRHQRMPNECKPITESPESIEVD
What is the function of this protein?
Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression (PubMed:16537907, PubMed:17662997).  Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells (PubMed:27181681, PubMed:16537907, PubMed:17662997).  Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation.  It is unclear whether it has histone methyltransferase activity in vivo.  According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a (PubMed:16537907).  According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro.  'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (PubMed:17662997).
What are the official names of this protein?
Putative histone-lysine N-methyltransferase PRDM6, PR domain zinc finger protein 6, PR domain-containing protein 6, PR domain-containing protein in smooth muscle.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: 6PGD_SYNY3
Sequence: MQFNVAIMTKRTFGVIGLAVMGENLALNVESRGFPIAVFNRSPNKTEKFMAERAVGKDIKAAYTVEEFVQLLERPRKILVMVKAGGPVDAVINELKPLLEEGDMIIDGGNSLYEDTERRTKDLEATGLGFVGMGVSGGEEGALLGPSLMPGGTPAAYKELEPILTKIAAQVEDPDNPACVTFIGPGGAGHYVKMVHNGIEYGDMQLIAEAYDILKNGLGLSNEQLHEVFGQWNQTDELNSFLIEISTDIFAKKDPETGGHLIDYILDAAGQKGTGRWTVMSGLELGVPIPTIYAAVNARVMSSLKEERVAASGQLSGPSKTFSGDVEAWIPKVRDALYCSKMCSYAQGMALIAKASQEFGYDVNLPEIARIWKGGCIIRAGFLDKIKKAFKDNPQLPNLLLAPEFKQSILDRQGPWREVLMLANEMGIAVPAFSSSLDYFDSYRRAVLPQNLTQAQRDYFGAHTYERTDKPRGEFFHTEWLD
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: HEM3_CAMJ8
Sequence: MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTKELEESMLRKEAHLAVHSLKDVPSFFPRGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAKIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVNFVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQVPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELLKKAESMI
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CAF20_PICST
Sequence: MVKYTEDRLLELKEETYIPQPQILEAFNQMIESVKEHAAAEAEKHKAIKWNNGDTYIDEHGNERPYHHMNRRRASRTANKPSLRKKSVENVDEDGWATLSKPKRSFGADEGLEERAKFRESVREGTVGGSGTVKAKPNNKNLGSSKAVDPRDAIADKHTTTFNAFEALGDGDDDDDDE
What is the function of this protein?
Acts as an inhibitor of cap-dependent translation.  Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA (By similarity).
What are the official names of this protein?
Cap-associated protein CAF20.
What is the protein family that this protein belongs to?
Belongs to the CAF20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_CLOBL
Sequence: MKLTNYDIIRRPLITEKTMASMADKKYTFVVDIHANKSQIKNAIETIFDVKVEDVKTARIMGKTKRVGVHIGKRPDYKKAIVKLTEDSKTIEFFEGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL10_OCEIH
Sequence: MSGIIEKKKQVVEEIAEKFRASQTAVVVDYRGLDVAEVTALRKELREAGIEFKVYKNTMTRRAVEAVELTDLNDTLTGPTAIAFSNDDVVAPARILNNFKKDHEALEIKGGVIEGQVATLDQIKDLADLPNYEGMVSMLLSVLQAPVRNFAYVTKAVAEQKEEQGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: YQGF_CHLCH
Sequence: MPLYQRIVAIDYGTKRIGVAKSDPLGMFAQPIGTVDRAGLSKLLSPMVEAGEVQLVVVGYPLNRHGEQTAMTEVIDRFIESLRLEFPALPIETINEHCSSKSAMQLLVASGTSRKERKTKGRLDTAAACLLLSDYLEQQK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_PARMW
Sequence: MARQGDIHRVTGETDVKVRLDLDGSGQCQASTGVPFLDHMLHQISSHGLIDLEINAVGDTHIDDHHTNEDVGIAVGQALAQALGDRRGIHRFGHFAAPLDEALVQVALDCSGRPHLSYSLSIPSQKIGSYDTELVKEFFVAVVNNSGLTLHIRQLDGVNSHHIVEACFKAFSRALRMATEIDPRRAGAIPSSKGVLEQAGAN
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3515_ARATH
Sequence: MLSLQCLPPFFISVPNRSTNSCSTAPLRAVSDFAASPSTSISRRLILLRHAHSSWDDLSLRDHDRPLSKTGEADAAKVAQILSSLGWLPQLILSSDATRTRETLKSMQAQVDGFMEANVHFIPSFYSIAAMDGQTAEHLQNIISKYSTPDISTIMCMGHNKGWEEAASMLSGASIKLKTCNAALLQAFGNSWEEAFALSGPGGWKLEGLVAPDSSIFV
What are the official names of this protein?
Uncharacterized protein At3g52155, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the SixA phosphatase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AMSF_ERWAM
Sequence: MKRRELIRTAFSTIVATAALSSVSARARSEDLHGLTLKKVPPDAIPKNDVPIFSPDDVFTMPEQFWRDFKGKLYIGKAGTDPTLPQNLIDVFVKNANGGTALLSQPIDLNSETLKTFVAAKGALWSASEYSMALHNDNDEQIFYVPDVKNNGVSEFSRRLSQPGGYQLIGEISSFASLRQTRPLFSGAKVRLKGWHDGTEVGGGAFVGEMTPSEDDGGYIASSGQDFHWRRVSDDMNRITLFDFGAVADGKKDCLPAVMAMYHWAQNNNQKLSIQFPAGRFFISSFDISAKYIRFLRLAGAPVNFGYFPATTLVSDGKSEFLFKVNARWVELSNISFEGQIEHSPNGQGFFHNICPAGQYFRGSCLRFTGVGGVSLSLIDTLDCKIDQWYASKCTGDVIRGSWSFTKKGNWDHNTAIELSNFNVQHCRQGKVLNLPRCTQSIIHNGWIEHSEFPGDLSNGQWIVDALSLEGCKNPLIAHCSRLNMRQTNLQSGSWIDNSLANDEWLSSFERGSTRVESYGIAVDGSMKYNYLTSRFRIENHSSQEKWYELGNIHTPDVGDSWEIEVFGQSQFSNGSGTKALMSVTDDRHTGGKAIINLQRKIHGFEASWSVEGSSPINDVVYTTSNDSDTRVFVKLAQWLGSAGVMIKTTAKDRFVTGHCARFDSRMVHSEPPKGEKVHSAVRRFSLHNGLAGIGANEQGDLLVESRHIDAAKVETSRAEGYISLVINGQQVAVPYFALKQNS
What is the function of this protein?
Involved in the biosynthesis of amylovoran which functions as a virulence factor.  May be involved in the polymerization or late modification of the repeating units.
What are the official names of this protein?
Amylovoran biosynthesis protein AmsF.
What is the protein family that this protein belongs to?
To R.meliloti ExoP.
What are the subcellular locations of this protein?
Periplasm.
Protein: PGLZ_STRCO
Sequence: MTDTTVAVPGAVRLNTATVTQYLSSQSSLVASLTGDGGGRRRAVLLRSAPQWDGPAEPAWGEGRTAGIAVAPSPLAVHELVLDHLAARRPGPPVLVVLTDREQHELDPAILARVHKLRIDTVDGWDVVREAFGARQIDPRLKDVNWAAEALLDATPPGSWPAVPGGWLSRQYALTALAQRRLRLGRYDTEGGPRRPGDDRLDAQALLHWSTRPGAPERLLTLRGPERAGLTAFLGEEDQAGLAGRTLLALVDAERGEDAAAFGLVCAALWQHAEPAPETYRARGRAERYFGDRPPATGDQLDALVTVFGRATEEHVTTLLAAGHRTAGTDADQAREARRTTGTVLDRAAALARQFGAEEAVAASPVLRGGLEARFTAVGRALAAGDTTAVADAVRRLENHRLAAEPEESARIERARMGQRLARWLATDPPTDALTVADALRRHVAETGWADLALEHIEAGGDQGPVLKAAYDTLGTRVRDRRRQIDASFARSLAAWTQSGTQPGSMLTVETFLDRVVGPLVRRGEERRTLMLVLDGMSAAIANELGEELRRSWAEFDPLPEGDTPYRRAMAAALPTVTAVSRTSLFAGTLTKGTQADEKRLFPALKLWGGAPAAVFHKDDLRTETAGETFGPALTEALADGRTHVAVVLNAIDDRLAKEQKLGDGAWRIDDVPGLRDLLRVAATQGMAVVLTSDHGHVVDRHGTKVDPAAAPESARHRLIGGGPLAEREITLSGPRVIWPEPGASIVALWDADSRYTALKAGYHGGASLAEVTIPALAFLPFGAEPPKGWRELGDQRPVWWAPEETGKAPLPDEYTARPVAATASAPKKPTAKAKKDQAEVARMHHGALFDVALTTEGDDALLTPTVVSRTETLVTALLDSETYQAQLGGLARKPQQEQVHKALTTLLDSGGTLPVTALAQRVGMPVTRGVGFAAVLGQLLNYDGVQVLETLPDGRTLRLHAALLREQFALGAG
What is the function of this protein?
Probably an antitoxin component of a type II toxin-antitoxin (TA) system.  Inhibits the toxic activity of its cognate toxin PglX.
What are the official names of this protein?
Alkaline phosphatase-like protein PglZ, Bacteriophage (PhiC31) resistance gene PglZ, ORF2.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase superfamily.
Protein: PPD6_ARATH
Sequence: MATASLVPTSKIFSVSPKSSASIKARSRVVVASSQQQQQPRRRELLLKSAVAIPAILQLKEAPISAAREVEVGSYLPLSPSDPSFVLFKAKPSDTPALRAGNVQPYQFVLPPNWKQLRIANILSGNYCQPKCAEPWIEVKFENEKQGKVQVVASPLIRLTNKPNATIEDLGEPEKVIASLGPFVTGNSYDSDELLKTSIEKIGDQTYYKYVLETPFALTGSHNLAKATAKGSTVVLFVVSATEKQWQSSQKTLEAILDSFQL
What is the function of this protein?
May be involved in the redox regulation of photosystem II.
What are the official names of this protein?
PsbP domain-containing protein 6, chloroplastic, OEC23-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: FRLR_ECOLI
Sequence: MSATDRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATKEKVIEQERVSAAPFCEKLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEIYVEGSSTYQLFQERFDTRVVSDKKTIDIFAATRPQAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRITLTIDNKRH
What is the function of this protein?
May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine.
What are the official names of this protein?
Probable fructoselysine utilization operon transcriptional repressor, HTH-type transcriptional regulator FrlR.
Protein: MURB_BURVG
Sequence: MPMPPDDSPLSLLPDHPLAAHNTFGIAATARYAARITHAAQFEALHRDPRVASLPQLVLGGGSNVVFTRDFDGVVLLDEIGGRRVVREDDDAWYVEAGGGEPWHAFVAWTLEQGMPGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLIAVELATGRSERFDAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKRWTPRLGYADVTRELDARGIAPDAATPRDVFDAVVAIRRAKLPDPRVLGNAGSFFKNPVIDAAQFDALRARAPDVVSYPQPDGQVKLAAGWLIDQCGWKGRALGAAAVHERQALVLVNRGGATGVDVLALARAIQHDVRVRFGVELEPEPVCL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDA_STRP8
Sequence: MLFNINEKGEPLVISFAPFLSPEAIKYLQENERCSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTVSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIAHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKTEQGKVILLKENFRSQSEVLNVSNAVFSHLMDESVGDALYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQDITDPKKLGKLLSLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRLQTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKVTYEPLLEPIGVDIIEKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKLDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLMGGGKPEIVEV
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: PT122_YEAST
Sequence: MLTITKRLVTTDVRSRILLSSLNGKMSDALALLRQQQQTSVDVELLHTMLARAAALAHADTIAYMWYQHVMPRRLPVEGRLLCEMAGVALYQDRLFLPAQFLQHYQAMNRDRRTSPEDELIEYELRRIKVEAFARGTMHSTALREKWKVFLQEMDTLPGQPPLRLRDFPQMTKAMGIALMQQDEQAAALALFGRQPLVIKNEWSLPLLLAGVLWHVPGPAQARRVLAEFRQSYRGLPLLDAELVIKRRGFEINT
What is the function of this protein?
Required for expression of the mitochondrial gene for cytochrome c oxidase subunit 3 (COX3).  PET122 seems to work by directly interacting with the small ribosomal subunit to promote translation initiation on the COX3 mRNA.
What are the official names of this protein?
Protein PET122, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: PRP39_MOUSE
Sequence: MQNSHMEEYRNSDNGSTGNSSEVAVVEHPDFSTEIMNVTEMEQSPDASPSAHASTEENEMANAVNLPVTEAEGDFPPEFEKFWKTVEMNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFVHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIPLSVDLWIHYINFLKETLEPGDQETNTTIRGTFEHAVLAAGTDFRSDKLWEMYINWENEQGNLREVTAVYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDGPPGDDLPSGIEDISPAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHVKPLEKAQPKKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHSIEGVRHVFSRACTVHLPKKPMAHMLWAAFEEQQGNINEARIILRTFEECVLGLAMVRLRRVSLERRHGNMEEAEHLLQDAIKNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIEKDKENTKLYLNLLEMEYSCDLKQNEENILNCFDKAIHGSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDTLKRKAENGSEEPEEKKAHTEDLSSAQIIDGDLQANQAAYNYSAWYQYNYQNPWNYGQYYPPPPT
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-processing factor 39, PRP39 homolog.
What is the protein family that this protein belongs to?
Belongs to the PRP39 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHEB2_BURTA
Sequence: MIRVVVVDDSMSMRTLLERIINGCDGMTCVGAAEDASAAREMIRALDPDVVTLDVEMPGMDGLEFLRRMMLLKPTPTIMVSGRTTSGSDAALRALELGAVDVIAKPLLTRPADLADYARDIAELIRGAAAARVKGGALAAASSAGRERACAHRPRGAKKAGIAATRLSRVIAIGASTGGTEALRTVLQDMSGTPPPILICQHMPEGFTASFAARLDAICGIRVKEAEQGEPLHYGCAYVAPGHSHLSLAATGRLYVCRLEASPPVNRHRPSVDVLFDSVARLAGKRALGAILTGMGKDGAAGLLRMRASGARTFAQDEPSCVVFGMPKEAIAMGAVDEILPLARMGARLSEALQ
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMF_SHEB8
Sequence: MSKPAVKSVQSATAKTATRAVNIRQKVKAPKQAKPEAKGRVRPSKDKPRVEIKKALHPRNAHLNGYDFPALISAFPQLKTFVRPTPYGALSVDFADPLAVKTLNAALLKHHYGIGSWNIPEGALCPPIPGRVDYVHYVADLLAEGDKSCAMDKARVLDIGTGANGIYPILGCQVYGWQYVASDINAHSLTNVQSIIEQNPVLQGRISLRLQPDDKAVFKGVIQAEERFELTLCNPPFHASMAEASEGTKRKVNNLQLNRGSSVKAAPKLNFGGQAAELWCQGGERQFLATMIRESQMFADQCLWFTSLVSKQENLKPCYQALAQLNVDTVKTIEMQQGNKITRVLAWSFQSAAKRKLWRAEHLAN
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_ERWT9
Sequence: MKTFTAKPESVQRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNAEKVAVTGNKRSDKIYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMYRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MURQ_SALPB
Sequence: MNLGTLVSETRNPQTMDLDALPTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDCQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAEALLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: HIS2_MYCTA
Sequence: MQQSLAVKTFEDLFAELGDRARTRPADSTTVAALDGGVHALGKKLLEEAGEVWLAAEHESNDALAEEISQLLYWTQVLMISRGLSLDDVYRKL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.