PharMolix/UniProtQA huggingface dataset:
Protein: CAN13_HUMAN
Sequence: MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNVIWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSHQYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSYSDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQAMENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPRKSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGNTAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFREKFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDSDRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSLDECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTDFLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEMEWMSLVMYN
What is the function of this protein?
Probable non-lysosomal thiol-protease.
What are the official names of this protein?
Calpain-13, Calcium-activated neutral proteinase 13, CANP 13.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
Protein: LS14B_MOUSE
Sequence: MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMPPYGQLAASSLLSQQYAASLGLGAGFPSTPVGKSPMVEQAVQTSSVDNLNAKKLLPSKVTSATQLNGRQAQPSSKPASDVVQPAPVHTQGQVNDENRRPPRRRSGNRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKADKGEEKDPAVMAQSEETAAEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGRGNGTTRRNPTSHRAGTGRV
What is the function of this protein?
Required for oocyte meiotic maturation (PubMed:28458300).  May be involved in the storage of translationally inactive mRNAs and protect them from degradation (PubMed:28458300).  Plays a role in control of mRNA translation (By similarity).
What are the official names of this protein?
Protein LSM14 homolog B, RNA-associated protein 55B, mRAP55B.
What is the protein family that this protein belongs to?
Belongs to the LSM14 family.
Protein: UPP_THEP1
Sequence: MKNLVVVDHPLIKHKLTIMRDKNTGPKEFRELLREITLLLAYEATRHLKCEEVEVETPITKTIGYRINDKDVVVVPILRAGLVMADGILELLPNASVGHIGIYRDPETLQAVEYYAKLPPLNDDKEVFLLDPMLATGVSSVKAIEILKENGAKKITLVALIAAPEGVEAVERKYKDVKIYVAALDERLNDHGYIIPGLGDAGDRLFRTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: TRPB_SALAR
Sequence: MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAQVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKSQILDKEGRLPDAVIACVGGGSNAIGMFADFINDASVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAHLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREHPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RF1_CHLL2
Sequence: MFDKLQSIKEKHLDLEQQLADPSAASDQNRFRKLNKEYSDLKEIVHAFDRYSLARKQLEESRELLGSEKDPQMRELVQMEIEDLQEKLPELEQQLKVLLLPKDEADSRNVIMEIRAGTGGDEAALFAADLLRMYQRYAERQGWKCVLLDYTESSVPGGFREVTLEVSGHDVFATMKYESGVHRVQRVPDTETQGRIHTSAASVAVLPEAEEVDVEIRRDDLRFDTYRSGGKGGQNVNKVETAVRITHLPTGIVAACQEERSQLQNKERAMTMLRTKLYDIQLAEQQQQRADLRRSMVSTGDRSAKIRTYNYPQSRVTDHRIGFTSHALPQIMQGEIGDVIEALKLHDQTARLQAEQV
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_MYCSK
Sequence: MQFAKGHGTQNDFVLLPDLDARLALTPAVVSALCDRRRGLGADGVLRVTTAKAALSAGVFERLPEGVGAGDWYMDYRNADGSIAQMCGNGVRVFAHYLRAADLESRDEFVVGSLAGPRPVVLHGFDLAHRSRAEVTVEMGKVNLLGSGSAVVGGRRFTGLGIDVGNPHLACVDTTLTEAELAALDVAAPVDFDPAQFPDGVNVEVLTALRDGAVSMRVHERGVGETRSCGTGTVAAAVAALAQEGAAVGTLDVRIPGGVVTVSVTDTTSFLRGPSELVATGELAGEWWQSHQR
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGBA_HAEIF
Sequence: MTNFKFSLLACSIAFALNASTAYAAQPTNQPTNQPTNQPTNQPTNQPTNQPTNQPTNQDSNLSEQLEQINVSGSTENSDSKTPPKIAETVKTAKTLEREQANNIKDIVKYETGVTVVEAGRFGQSGFAIRGVDENRVAINIDGLRQAETLSSQGFKELFEGYGNFNNTRNGAEIETLKEVNITKGANSIKSGSGSLGGSVIYKTKDARDYLLNKDYYVSYKKGYATENNQSFNTLTLAGRYKKFDVLVVTTSRNGHELENYGYKNYNDKIQGKRREKADPYKIEQDSTLLKLSFNPTENHRFTLAADLYEHRSRGQDLSYTLKYLKTLPDLPEVDSRHTNDKTKRHNISFSYENFSQTPFWDTLKITFSKQKIKTRARTDEYCDAGVRYCEGTANPAGLKLKNGEITRRDGTPLQFKEINNTTTPNSNSNKDKTYDFSKLIDTNGKEIESGITRSNDTFWYDCSIFDCENPGKMKVAEGKTYYRYDGTWKNNVQLEKKVLNGKEFARINNGTRGKTFPILPSSLGYLERLWQERDLDTNTQQLNLDLTKDFKTWRVEHNLQYGSSYNTTMKRMVNRAGYDATDVQWWAKRTLGTRFDFLKNEEIVETCATTFGWNAFLCPRVDPEFSYLLPIKTKEKSVYLFDNVVITDYLSFDLGYRYDNIHYQPKYKHGVTPKLPDDIVKELFIPLKSGQNNNDAEVKKNVQENIDYIAKQNKKYKAHSYSFVSTIDPTSFLRLQLKYSKGFRAPTSDEMYFTFKHPDFTILPNTHLKPEIAKTKEIAFTLHHDDWGFISTSLFKTNYRDFIDLVYKGEREFEVGNPNNRGKISFDTFQNINRDSAVVKGIEINSKVFLGKMAKFMDGFNLSYKYTYQKGRMDGNIPMNAIQPKTMVYGLGYDHPSQKFGFNFYTTHVASKNPEDTYDIYAKDKNQTNTSIKWRSKSYTILDLIGYVQPIKNLTIRAGVYNLTNRKYITWDSARSIRSFGTSNVIDQKTGQGINRFYAPGRNYKMSVQFEF
What is the function of this protein?
Acts as a receptor for hemoglobin of the human host and is required for heme uptake.
What are the official names of this protein?
Hemoglobin-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. Hemoglobin/haptoglobin binding protein subfamily.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: KPRS_NITEU
Sequence: MSYDSLMVFTGTANPKLAHDVVKYLNINLGRANVGRFSDGEVMVEILENVRGNDVFVLQSTCTPTNDSLMEILVIVDALKRASASRVTAAIPYFGYARQDRRTRSARVPITAKVVANMLTSVGVDRVLTMDLHSDQIQGFFDIPVDNVYGMPILLGDIWKHDYQNLIVVSPDVGGVVRARHLAKRLECDLAIIDKRRPKPNESKVMNIIGDVRGRTCVIIDDMVDTANTLCEAASALKREGAASVIAYSTHAVLSGKAVERVQTSDLDKLVVTDTIPLREDASKCNRIHQLSVASLLGESMLRISNESSLSSLFIE
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP51A_HUMAN
Sequence: MAAAAGMLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTLSLVYLIRLAAGHLVQLPAGVKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRSK
What is the function of this protein?
Sterol 14alpha-demethylase that plays a critical role in the cholesterol biosynthesis pathway, being cholesterol the major sterol component in mammalian membranes as well as a precursor for bile acid and steroid hormone synthesis (PubMed:8619637, PubMed:9559662, PubMed:20149798).  Cytochrome P450 monooxygenase that catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of sterols such as lanosterol (lanosta-8,24-dien-3beta-ol) and 24,25-dihydrolanosterol (DHL) in the form of formate, and converts the sterols to 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol and 4,4-dimethyl-8,14-cholestadien-3beta-ol, respectively, which are intermediates of cholesterol biosynthesis (PubMed:8619637, PubMed:9559662, PubMed:20149798).  Can also demethylate susbtrates not intrinsic to mammals, such as eburicol (24-methylene-24,25-dihydrolanosterol), but at a lower rate than DHL (PubMed:9559662).
What are the official names of this protein?
Lanosterol 14-alpha demethylase, LDM, CYPLI, Cytochrome P450 51A1, CYP51A1, Cytochrome P450-14DM, Cytochrome P45014DM, Cytochrome P450LI, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: YPI1_PICGU
Sequence: MAQQGSSQMRPQGTSSVTQTTTETSASPILHLRPSKRKSKKKPSVRWTEDTVDNEHMNKKKTKICCIFHPQRQFDDGSSCESCSSSDSSSDGSDTEDSKPNAYEHQPHYKNQSKVPQ
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
What are the official names of this protein?
Type 1 phosphatases regulator YPI1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CATA_PEA
Sequence: MDPYKHRPSSAFNSPFWTTNSGAPVWNNNSSLTVGSRGPILLEDYHLVEKLAQFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNYDLVGNNFPVFFVHDGMNFPDMVHALKPNPQTHIQENWRILDFFYNFPESLHMFSFLFDDVGVPQDYRHMDGFGVNTYTLINKAGKSVYVKFHWKPTCGVKCLLEEEAIQVGGSNHSHATKDLYDSIAAGNYPEWKLYIQTIDPAHEDRFEFDPLDVTKTWPEDIIPLQPVGRMVLNKNIDNFFAENEQLAFCPAIMLPGIYYSDDKMLQTRVFSYADSQRHRLGPNYLQLPVNAPKWSHHNNHHEGFMNAIHRDEEVNYFPSRHDTVRHAERVPIPTTHLSARREKCNIPKQNHFKQAGERYRTWAPDRQERFLRRWVEALSDTDPRITHEIRSIWVSYWSQADRSLGQKLASHLNMRPSI
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ICK36_TRILK
Sequence: MKTIIVFLSLLVLATKFGDAKEGVNQKQKKEVTQNEFREEYLNEMAAMSLVQQLEAIERALFENEAGRNSRQKRCLGENVPCGDNIPCCGKLACEKTAGYGWWYKSPYCVKPTSG
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U17-barytoxin-Tl1b, U17-BATX-Tl1b, Toxin ICK-36.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 03 (ICK-30-40) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_SYNY3
Sequence: MDYRQAGVDVEAGREFVSRIRQQVESTFRPEVMGGIGGFAGLFEIPAGYKAPVLVSGTDGVGTKLKIAQAMDQHHTIGIDLVAMCVNDILTTGAEPLYFLDYLATGKLEPAQLADVVTGIVEGCKQSGCALLGGETAEMPGFYGAGEYDAAGFAVGIVEKSQLLNGSQVNIGDVAIAVESSGVHSNGFSLVRKIIESNGWQWSDCLPEWGGQSLGEIFLEPTRIYVKPIQALLKSGINIHGMAHITGGGLPENLPRCLGQGQSIQVKAGSWQPLPVFNWLADKGQVNSTAMLETFNLGVGFVVLVSPEQRQTTLDFFSGQGLVANQIGTVIEGDGAFVWLD
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG1P_LODEL
Sequence: MPKTAKKHHRKSNGPIEVSSAIHTGSSAKLKKKIRDIERALKKHEKLPADKKIEYERALKGLQVELQNSQKNLKEKENASKYHMVRFFERKKATRKLKQLRKQFDEMQNTAEPSKKELKKLRKQVKHGEIDLLYVCLFPKAEKYISLYPSQSAEDINDPNVKAGLRKTEAKRLQFRKEVEKLMDEGKLLFTVDDILAGKKVYHEFYKSSTTEKEIDAPAAKEEGENGEEQDDFFE
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MSRQ_ECOLI
Sequence: MRLTAKQVTWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLRSLFNRLRKQVHNKLSV
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUSB_ACTP7
Sequence: MKVSPRRRARECAVQALYSWYVSQNSVEEVELSFVTDQDMNGVDLPYFRKLLRGTVLYVEAIDNDLRPFLDRAEDEVDPIERTILRLSAYELKYELDVPYKVVINEGIEVAKVFGSDDSHKYINGILDKLAPALGRK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CN132_HUMAN
Sequence: MDLSFMAAQLPMMGGAFMDSPNEDFSTEYSLFNSSANVHAAANGQGQPEDPPRSSNDAVLLWIAIIATLGNIVVVGVVYAFTF
What are the official names of this protein?
Uncharacterized protein C14orf132.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KAPR_YEAST
Sequence: MVSSLPKESQAELQLFQNEINAANPSDFLQFSANYFNKRLEQQRAFLKAREPEFKAKNIVLFPEPEESFSRPQSAQSQSRSRSSVMFKSPFVNEDPHSNVFKSGFNLDPHEQDTHQQAQEEQQHTREKTSTPPLPMHFNAQRRTSVSGETLQPNNFDDWTPDHYKEKSEQQLQRLEKSIRNNFLFNKLDSDSKRLVINCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSSGPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVDVSKKGQGVINKLKDHDYFGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLLGPAVDVLKLNDPTRH
What is the function of this protein?
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), an effector of the Ras/cAMP pathway.  Inhibits PKA activity in the absence of cAMP.  cAMP activates PKA and promotes growth and proliferation in response to good nutrient conditions.  Together with ZDS1, provides a negative feedback control on the cell wall integrity-signaling pathway by acting as a negative regulator of MAP kinase SLT2/MPK1.
What are the official names of this protein?
cAMP-dependent protein kinase regulatory subunit, cAPK regulatory subunit, Bypass of cyclase mutations protein 1, Protein kinase A regulatory subunit, PKA regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic when phosphorylated. Nuclear when not phosphorylated.
Protein: GDIR1_MOUSE
Sequence: MAEQEPTAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVAVSADPNVPNVIVTRLTLVCSTAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPMEEAPKGMLARGSYNIKSRFTDDDKTDHLSWEWNLTIKKEWKD
What is the function of this protein?
Controls Rho proteins homeostasis.  Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.  Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation.  Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms.  Through the modulation of Rho proteins, may play a role in cell motility regulation.  In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1.
What are the official names of this protein?
Rho GDP-dissociation inhibitor 1, Rho GDI 1, GDI-1, Rho-GDI alpha.
What is the protein family that this protein belongs to?
Belongs to the Rho GDI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y0777_DICDI
Sequence: MDHITMEEKINKKTKHIFSNNYDNILSDKQVQCIYKEFFNNNKDNNNNKRFNENGNQINQIDFNSNKEEEKEEKEEKEKEEDEDNITILDDVYYSLEYDFEDYIKYSKILTEKIEKERITQLFEQEKQNRLIRYHQRIQQQKVIKEQLNVNMELLEKRKLLETELSLKSNQLNQCQTQLQQFQSTMTLLQSQHQQTINKLKQTQSEQLQKRRNQQHQNLLKKQKIQKEKEEREQKEKEQKEKEQKEKEEQQQQLFLLQQQQQQEEESKTTNKKKRNSRTTSINRVFRSLLTDVKVPAKKFNGLKSEAQEEMYDQLDTVLNQLKDYSDHSFPFLTKVRPSEAPNYYEIIKKPMDLSLMTKKLKKLEYQSKFEFQLDLNLIFTNCRIYNTDPSGKVYVEHANKMEKKSKDLMKNVKDLDFSMDILKDIVDENKNNNNSNNSVDNNNSLKKGRTSTPNKKQKTSNSTTTTTTTTTTTTATTPNLLNTPLSSPPYTPCSPSTISTVSSTPTTPQSADCPLSPFQQQQQQQTQAQQQPTSNSPRNTTTTTTTITSPISPRETNKDVIMEEEEESSSSSLSSSSLALNSQNENGVNKSIEDSTGVKMESEESTNVKKEENQSGDCENQTTTTTTKEEGEEQQEQEDEEQQQQQQQQEEQTLEIENEEDIINNFNSEIESLNNDFSEKTLQLSIQIKEISEKTEHFKINNSKIQQNLDELPLADKLNLDINNAKELVDDNIELDDSEIIIPPYLNNNNNNCNNNNNNNDNNNNNNIDNDNDNNNNNSLENSFEIEKSKKINKFKELTKENRVRKLKYFLDQQSLPFNKREAFIRTPYFMNTFYNLDLQQQNQKQQQIFNQEINDNDDDNNNNNNNNNNNNNNNNNNNNNNNKPKVMSAIQKMDQDFMDLKVGFFPELTHLSNSIPIITPNYPITCKNSSIDNSVTTPSKSLLRLLNSSKSNNNSNNKKEKQCNYNREGEDDEGRGEEQKEKEEEKEDEDFPNIITNDIAYILLSKSIAKSIESESCLHGTTQETMLIFTDIVSSFIGKIGKLFNKYYSNNGLPNNKSTTTQTTPTTQLQPPPPPPSLSLPPSLLLNSIVTDIFGDSLGILLLKDYMIKKSKNQQIYDDPLFELEVEFENDHLQSDNILQNNNGDIDINESMEIDILGEDDIIDIDDTGLFGHYPRYIEEPAEITLFIDPKPIQKPTTNTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSINNNNHNNNNNNNNNINNNNNNNNNNNNNNNNNNNINNNNNNNINNNNNNINNYNNNYNNNNNNNNNNNNNNNNNNNNNNNNNYPKPIQASTQTGNLGIQQQLQQQQLHQLQQQQQLQQQYQIQQQQLHLQQQQQQQQQLKLQQIQFQQMQQQQQQQQLQQQTRQPSQPQTPQMQSQPQTPQILSQPQQQLQQLQQQQLQQQQQLQQQQLQQQQLFQQQQQQQQQQQQQQQQQQQQQQQQQQLLHPQQMQIQQNLQQPLQQIQQQQQIQQQQQQQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHQQLQQLQPQQQQQLQQLQPQQLQQLQQLQQLQQLQQLQQLQPQQLQQLQQLQQLQPQQLQQPQQLQPQQLQQQQLQQQQQPQQQQQQPQQQPQQQPQQQQQPQYQTTFQSIASPKEKDKEREKEKEREREKEKDRKFKKVKKTESKKESKKSLNDSSNSDINTSVEQHSPLSPQPISSSKPTPPPVSSKQPQTTQSNTTTTQDSIPPIEQKKKRGRPQKKQ
What are the official names of this protein?
Bromodomain-containing protein DDB_G0280777.
Protein: ILVC_BRASB
Sequence: MRVYYDRDADLNLIKGKKVVIVGYGSQGHAHALNLKDSGVKDVAIALRKGSASAKKAEGAGFKVMEVAEAAKWADLVMMLTPDELQGDIYREHLHDNMKQGAALVFAHGLNVHFNLLDPRPDLDVLMIAPKGPGHTVRSEYQRGGGVPCLIAIAKDSSGNAHDLGLSYASAIGGGRAGIIETTFKEECETDLFGEQAVLCGGLVELIKAGYETLTEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLDDIQSGRFARDWMLENKVNQSSFKATRARLAQHPIEEVGARLRDMMPWIKKGALVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RL29_PROMM
Sequence: MAHPKAAEVRKLTDADITEQIDGIRRELFDLRFQQATRQLSNTHRFKEARIKLAQLLTVQKERSRSAASS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HBG2_CEBAL
Sequence: MSNFTAEDKAAITSLWAKVNVEDAGGETLGRLLVVYPWTQRFFDSFGSLSSPSAIMGNPKVKAHGAKVLTSLGEAIKNLDDLKGTFGQLSELHCDKLHVDPENFRLLGNVLVTVLAIHHGKEFTPEVQASWQKMVAGVASALGSRYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma-2, Gamma-2-globin, Hemoglobin gamma-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TRPD_LACP7
Sequence: MIKEAIYQLVNKEDLSYEVAEQVMDEIMSGEASNVLIGSYLTALRMKGETIDEITASAAGMRKHCVRLLHNMDVLEIVGTGGDEANTFNISTTTGFVVSAAGIPVAKHGNRCVSSKCGAADVLEALGVNIMLAPLESAKILEEMGLCFMFAQTYHSAMKFVAPVRRELGIRTIFNILGPLANPAGANLELLGVYEEALVKPLARVLLKLGVKRGMVVYGRDGLDEISLSHQTVCCKIRDGKLYDYILEPEQIGLTKCKKEDLVGGSPAENAAITRAILNGEKGPKRDAVIFNAAACIYMVRDDITLQEAAKIATDIIDSKKAIHQLDKFIELSNRR
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SHO1_CANGA
Sequence: MSGRRGKIINPRTRGAVRNVGFRNLISDPFAISSILIGLISWVITLGGCISVQVNEDFPRFTWWGIAFQFLIILMLIGFYIYDLVDYYRNFLTASIGVAFVYSTNSANYLIYGSGNQKAAASAGVVLLSMVNLIWIFYYGGDNASPINRWVDSFSLNGIRPSPFEAAKIKAYRRSSKQTQFRGSSVKLTHSTNNLHSASENLGLDNGFYNNPHTSNYVSSTALTEFENTGPPYPSASDLPTNNNAPLRSPQLGNNTIGDTYITATTNNNTNTTMGDTMGLYADLADESFPYRVKALYSYEADSADAYEMSFEQGEILMVSDIEGRWWKAKKESGETGIIPSNYVTIIDNDTEA
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL36_BRUME
Sequence: MKIKNSLKALKARHRDCQLVRRKGRVYIINKTAPRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TPM_PENMO
Sequence: MDAIKKKMQAMKLEKDNAMDRADTLEQQNKEANNRAEKSEEEVHNLQKRMQQLENDLDQVQESLLKANIQLVEKDKALSNAEGEVAALNRRIQLLEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEVARKLAMVEADLERAEERAETGESKIVELEEELRVVGNNLKSLEVSEEKANQREEAYKEQIKTLTNKLKAAEARAEFAERSVQKLQKEVDRLEDELVNEKEKYKSITDELDQTFSELSGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin, Major allergen Pen m 1, Tropomyosin, fast isoform, Tm-Penm-fast.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.