PharMolix/UniProtQA huggingface dataset:
Protein: UCP7_SCHPO
Sequence: MDDLLDFNFYDKSTPSNQNNYSNNNSRTPSYSLPAPVAQKKNAQIPLKASKPEDPFANLFQKKTDNKISLKELERQKVGTPDSNSTPKSSNYDPFENLEILHQLSNTPRDKDAVIHDKIEENKRPISQPQVSASEKVTLKDLSLEPHQPVSLPAFENIGSETSIPFENHNEITNMNTAKDKLSSNEMYEKLRDLGFSDDQSRLALENSGSLEDAIEYILEKDNAKGQYREGEAYEAFSDSSAKTQFSDFQALSNQLKSQLFEKANDLWNIGRKKLRDAVEERRAVKDPSKPRWMDASHDFGREATPEILPKTPIPKRKPHKVPMNEKVSEDRITTNQSRSGNDESSLVDFLTSKSDNSSFNFPSDTYEGTENILETAYESTTARQVNNNKPGKSTVKKREEETLNNMVSALVEEQQSTGNELFRKGDFSQAIEEFTNSLSQLPAKHTKRVPLLSNRSLCYQKVGDLKTCLQDVDELVDIIGEEKGHGESIRDKSMNDYYVKNMVRKAQVLEQLEKYQESLNIWKDLIADGQISKLYIDGKHRCEAAISSHSSESHSKRTTQQPKSTPNHTNIKVKSERLQHVRMAQQKAEQLDEERSRLREPVQQIVNKWKEGKESNLRALLASLDTILWPECRWQKVSLSELVLPKKVKIAYMKAVSRVHPDKLPQQTSVEHQLIAESAFSILNHAWELFKQQNDL
What are the official names of this protein?
UBA domain-containing protein 7.
Protein: ENO_FASHE
Sequence: MAIKAIHARQIFDSRGNPTVEVDVTTAKGLFRAAVPSGASTGVHEALELRDGPPGYMGKGVLKAVANVNSQIAPNLIKSGINVTDQAAVDKFMLDLDGTPNKEKLGANAILGVSLAXCKAGAAEKGLPLYKYIATLAGNKEVIMPVPSFNVINGGSHAGNKLAMQEFMIMPTGASSFTEAMKIGSEVYHNLRAVIKSKYGLDACNVGDEGGFAPSIQDNLEGLELLRTAIDKAGYTGKVXIAMDCAASEFYKEGKYDLDFKNPKSQASSWITSDAMADVYKKMMSTYPIVSIEDPFDQDDWPAWTKLTGECKIQIVGDDLTVTNPLRVQKAIDQKACNCLLLKVNQIGSVSESIKACKMAQEAGWGVMVSHRSGETEDNFIADLVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEDLGGAAKYAGENFRRP
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_MYCBT
Sequence: MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: MURG_STRMU
Sequence: MAKKKIIFTGGGTVGHVTLNLLLIPRFLKDGWEVHYIGDKHGIEHEQIEQSDFDVIFHSIATGKLRRYFSLKNVLDVFKVGWGVLQSLTIMVKVRPQVLFSKGGFVSVPPVVAANLLRIPVFVHESDLSMGLANRIAYKFATTMYTTFEQSDNLTKTKHVGAITKVNQTISSSDDNTEIKTIKEYFDPRLKTLLFIGGSAGAKVFNQFISDTPELTKHYNVINISGDKTLNNLSQNLYRVDYVTEMYQPLMDLADVVITRGGSNTIFELLAMAKLHIIVPLGKEASRGDQLENAAYFEEKGYAQQLSEENLNFAELDKVIKDLLENQTVYQDKMTSSSEIKTPNDFYNLLLTDITSKSKGK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MSCL_SHESM
Sequence: MSLIKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSIVLQAAQGDAPAVVIAYGKFIQTVIDFTIIAFAIFMGLKAINSLKRKQEEAPKAPPAPTKDQELLSEIRDLLKAQQEK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS15_SHEWM
Sequence: MSLNAEQTASILAEFGRCENDTGSTEVQVALLTAQINHLQGHFKEHKHDHHSRRGLLRMVNTRRKLLAYLKRTENVRYQELIKKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: URE3_ROSDO
Sequence: MQLTPREKDKLLISMAAEVARKRLARGVKLNHPEAIALITDAVVEGARDGRSVADMMEAGAQVITRDQCMEGVPEMIHDVQVEATFPDGTKLVTVHNPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_HISS2
Sequence: MNKSYLYSFFFHGSLVKRISVGLLLGLLLALIAPSLQGVLGFNLAEKAGFLGKIFVRSLRAVAPILVFLLVISAIANKQLGTKSNMKSIVVLYLLGTFLAALTSVLFSFALPTEIALKTQEGSLSPPNEVSEVLSTLVLNVVDNPINALFNANFIGILFWAIGLGIALRYASDTTKNVMNDFSEAVSRIVHFIISFAPIGVFGLVAETLTDKGLGALLDYMQLLVVLIGSMLFTAFVINPILVFWKIRRNPYPLVWTCVRESGLTAFLTRSSAANIPVNMELSKRLKLDEETYSVSIPLGANINMAGAAITITVLTLAAVHTLGIEVSFPTAVLLSVVASICACGASGVAGGSLLLIPLACSLFGIPNDIAAQVIGVGFVIGVLQDSTETALNSSTDVIFTAAVCWSEENKNS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IMDH1_DANRE
Sequence: MADYLISGGTGYVPEDGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAKVRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTLKEANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTREDDKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKRYFSEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRTMSAQVEGGVHGLHSYSFLPFTRNGYIEPGSRGHPRAGPNVPSPAVTKHSS
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase 1a, IMP dehydrogenase 1a, IMPD 1a, IMPDH 1a.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KUP_PSEPG
Sequence: MVQASSHAEGGHEGKQGAARSLGLLVAAVGVVYGDIGTSPLYTLKEVFTGGYGVPVNHDGVLGILSLILWSLLWVVSFKYVMFILRADNQGEGGTMALTALARRATAAYPRLRTLMVICGLIGASLFYGDSMITPAVSVLSAVEGMGLAFDGIDHWVVPISLVVLVALFLVQKHGTETIGKLFGPIMVTWFVVLGALGVHGISQSPEVLKAFNPGWAVNFFVVHPGMGVAILGAVVLALTGAEALYADMGHFGRKPIARAWFILVLPALVLNYFGQGALLLQNPEAARNPFYLLAPSWALLPLVGLATMATVIASQAVISGAFSLTRQAIQLGYIPRMQIQHTSSDEQGQIYIGAVNWTLMVGVVLLVIGFESSGALAAAYGVAVTGTMLMTTILVSAVMLLLWKWPPVLAVPLLMGFLFVDGLFFAANVPKIVQGGAFPVLAGGVLFLLMSTWKRGKQILVERIDEGALPLPLFISSIRIQPPHRVEGTAVFLTARSDAVPHALLHNMLHNQVLHSQVVLLTVVSEDQPRVPEHERFEVEAYGDGFFRVLLHFGFMDEPDVPAALKLCHLDDLDFTPMRTTYFLSRETVIASRLEGMSRWRGNLFAFLLKNANGNLRFFNLPLNRVIELGTQVEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHNC_LACAC
Sequence: MADKPMIQLKDVSKIYDNGTVGLKDINLKINKGEFVVVVGLSGAGKSTLLRSINRLHDISSGDILIDGKSITNAKGKNLRELRRDIGMIFQNFNLVKRSSVLRNVLVGRVAYYPTWKTTFNLFTKEDKQKAYEALQKVDLADKVYARADELSGGQQQRVAIARVLMQNPKIILADEPTASLDPQTSVRVMNDLKMLNEKYGMTVVANLHSIELAQQFGKRVIGIRAGQVVYDGKMEDTPKSVFTDIYNGGDGNEGAE
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DAPB_SYMTH
Sequence: MQPIRVVLAGATGKVGQVLARALVQEPGFALTGAIARQGGGRNLAELVPLGGRPGPTVHGSLEEFLAAGGEADVLVDFSVAEAGRRTIPAAIEASIAPVVGTTGFQPGETETWAAMCRKRGLGGAFIANYAVGIMLLMRFAEEAHRFFPDVEIIEMHHKTKLDAPSGTALRTKARLERGRGDLAAAEVPVHSVRLPGLVAHQEVIFGGLGQTLTIRHDAPSREAYVPGVLMTCRWVLREKRVAFDLEEVAFPRT
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CODY_BACAH
Sequence: MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLFNITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLHELAKLKTN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUC7_HUMAN
Sequence: MKTLPLFVCICALSACFSFSEGRERDHELRHRRHHHQSPKSHFELPHYPGLLAHQKPFIRKSYKCLHKRCRPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNKISRFLLYMKNLLNRIIDDMVEQ
What is the function of this protein?
May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing.  Binds P. aeruginosa pili.
What are the official names of this protein?
Mucin-7, MUC-7, Apo-MG2, Salivary mucin-7.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMN_ROSCS
Sequence: MTALPVTNRDTLPNLYDLSLAEMERLLTDWGQPTYRARQVFRQLYVNLADTPLAMTDLPLALRERLANETRLAPVTPEQVQTADNGLTRKALFRLPNGALVESVLMIYLDRATVCVSTQAGCAMGCVFCATGTLGLLRNLSPGEIVAQVVWAAREMRRLAGRPPRPTMRQPEDDAWWSPDDLENDAPSVPEVSSVSHVTNIVFMGMGEPFATYDRWWRAVEIIHDPRGLNIGARSMTVSTVGLVPGIRRLATETLPINLAVSLHAPDDDLRSALMPINRRYPLAVLLDATRDYLAATGRRVSFEYVLLQGKNDEPEHAAKLAALLRGEAGPAGLPLHLVHVNLIPWNPVPGMPLGRSERRRVLTFQRILRERGIACTVRVERGVAIAAACGQLAGGVAC
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AEP1_MESMA
Sequence: MKLFLLLVISASMLIDGLVNADGYIRGSNGCKVSCLLGNEGCNKECRAYGASYGYCWTWKLACWCQGLPDDKTWKSESNTCGGKK
What is the function of this protein?
Shows anti-epileptic activity.  Shares high homology with depressant insect toxins, but shows very weak toxicity against mammals and insects and no obvious symptoms on insect larvae.  May target voltage-gated sodium channel (Nav).
What are the official names of this protein?
Toxin BmKAEP, Anti-epilepsy peptide, BmK AEP.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL11_CHLT2
Sequence: MSNKKIIKIIKLQIPGGKANPAPPIGPALGAAGVNIMGFCKEFNAATQDRPGDLLPVVITVYSDKTFSFVMKQSPVSSLIKKALGLESGSKIPNRNKVGKLTRAQITAIAEQKMKDMDVVLLESAERMVEGTARSMGVDVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CLPS_SHIB3
Sequence: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: TRMB_MYCMS
Sequence: MRLRKKNWTDDFLNQHSFYLINYNNKKIDLKQIFLNNNPTCLEIGSGKGQFITTLALKNLNTNYIGMEKSSTITGVALKKSLKEFENQLKDMTNLKYFNNFAEDLSQMFSSDSFNKIYLNFSDPWPKTRHYKKRLTYVKFLDIYSDILIKNGYLEFKTDNDSLYNFTIEQLNLTNKWEIVINATDLYNNTEFLKDNIPTEYETKFHLANKNIYKIVIKNLK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: CMOA_SHEPA
Sequence: MNSSQDNLFAKPYEHVSDFQFDDKVAGVFNDMIRRSVPGYGQIINTIGDLAQKYATPNSKIYDLGCSLGAATLSIRRRVEGRNCQIIAIDNSESMIERCNENLSAYVSETPVELVCGDIRDIKIENASLVVLNFTMQFLAPSDRESLLKNIYQGLVPGGLLVLSEKLYFKEDNIQTTLDDLHLDFKRANGYSELEISQKRSSLENVMKPDTLVEHENRIRAQGFSQFSVWFQCFNFASMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RS9_BARBK
Sequence: MAELNSLSELSAVTNAVEVNKNIAPVHVQKLDSQGRSYATGKRKDAVARVWIKPGTGKITVNNKEFEQYFARPVLRMILRQPIVIAKRDTQYDVVATVAGGGLSGQAGAIRHGISKALTYYEPALRTILKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: YP162_YEAST
Sequence: MYVSNGKDTCQLLGPVSLFVQTLMGMTAVIVLLVKRNYEHPRRKMIVWSYDIGKQIIGSLGIHFLNLGISILKKRRRSLFAITAKGNDDEDQCDWYFLNLLLDTTVGIPILWLCLYIIEKVLKSLHFQNIESGNYFPSKTVGSHPRKPLFSAFVKQLLIFIVGLGVMKFCVFLILNYLEDLAYWFADLILGWSDSWPNFQVFLVMFVFPILLNCFQYFCVDNVIRLHSESLTITNAENFETNTFLNDEIPDLSEVSNEVPNKDNNISSYGSII
What are the official names of this protein?
Vacuolar membrane protein YPL162C.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RL14_XYLFT
Sequence: MIQMQSYLGVADNSGAKEVMCIKVLGGSKRRYASIGDVIKVTVKEAIPRGKVKKGEVYDAVVVRTRSGVRRPDGSLIRFDGNAAVLLNNKQEPIGTRVFGPVTRELRSEKLMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: FABP7_MOUSE
Sequence: MVDAFCATWKLTDSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGGKVVIRTQCTFKNTEINFQLGEEFEETSIDDRNCKSVVRLDGDKLIHVQKWDGKETNCTREIKDGKMVVTLTFGDIVAVRCYEKA
What is the function of this protein?
B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development.  It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.
What are the official names of this protein?
Fatty acid-binding protein, brain, Brain lipid-binding protein, BLBP, Brain-type fatty acid-binding protein, B-FABP, Fatty acid-binding protein 7.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_FLAJ1
Sequence: MSSIIQLLPDHVANQIAAGEVVQRPASVVKELLENAVDAKATDIKLIIKDAGKSLVQVIDNGVGMTVTDARLCFARHATSKIRQAEDLFSLGTKGFRGEALASIAAIAHMEMKTKQEQDELGTHIVIEGSKFVSQEVAVLPKGTSFAVKNLFFNIPARRNFLKSDTVEFRHVMDEFQRVALAHPNIHFSFYHNGSELYNLPAAGYRQRIVGIMSGKTNEKLVPVNEDTEIISIQGFVCKPEFAKKNRGEQFFFVNDRFIKSGYLHHAVMAAYDGLLKDGSQPSYFLYLQVPPNTIDINIHPTKTEIKFDDEQALYAILRASIKHSLGQFNVAPVLDFDRDSNLDTPYHYKDVEAEVPTIQVDGTFNPFTDDKTNQHYTKAGSGSGSGYSSGSSSSSGSGSGSSYSGYSKRVEPTVSWESLYVGLDTENPETIESSPFIFENEEVTSSLFNDDEVEQASQKTYQIHKKYIVSPIKSGMVIVDQHRAHQRILYEQFLLNMTVNQASSQQLLFPLDLFYSSSEMKLIEELKPSLETTGFVFEEAQTDHVVISGIPVNITESEVSLVIEQLLSDLQDGIPASSYSQNDTIAKSMAKSLAVKTGSYLTEKEQDNLVNGLFACKDPNISPFQKPTFITMRVEDIDKKFAL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PNP_SYNSC
Sequence: MQGQTQSISFDGREIRLTTGRFAPQAGGSVLVECGDTAVLVTATRSGGREGIDFLPLICDYEERLYAAGRIPGSYMRRESRPPERATLTARLIDRPMRPLFPSWLRDDLQVVATCLSLDERVPADVLAVTGASIATLLAGIPFNGPMAAVRVGLLGDDFVLNPSYREIERGDLDLVVAGTPDGVVMVEAGANQLPEQDVIEAIDFGYEAICELIKAQEQLLKDLGITQVKPEKPDEDSTVPAYLEKQCSKAISAVLSKFDQSKDERDTALETVKGEVSETIAGLKEDHAVRQALASSPKLLGNSFKALTKKLMRQQILKDGKRVDGRGLDEVRQISAMAGVLPRRVHGSGLFQRGLTQVLSTATLGTPSDAQEMDDLHPNTEKLYLHHYNFPPYSVGETRPMRSPGRREIGHGALAERAILPVLPEKDTFPYVVRVVSEVLSSNGSTSMGSVCGSTLSLMDAGVPLKAPVSGAAMGLIKEGDEVRILTDIQGIEDFLGDMDFKVAGSEKGITALQMDMKITGLSVKTVAEAVNQARPARLHILEKMLEAIDTPRDNLSPHAPRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGAAAEEAQKIIEGLTRKVNEGEVFSGSITRIIPIGAFVEILPGKEGMIHISQLSEARVEKVEDVVKVGDEVTVRVREIDNRGRINLTLRGVPQAGDAADVEPQPTPVAPLS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GACA_PSEU2
Sequence: MIKVLVVDDHDLVRTGITRMLADIDGLQVVGQADSGEESLKKARELKPDVVLMDVKMPGIGGLEATRKMLRSHPDIKVVAVTVCEEDPFPTRLLQAGAAGYMTKGAGLAEMVQAIRLVFAGQRYISPQIAQQLALKSFQPQVNNSPFDLLSEREIQIALMIVGCQKVQTISDKLCLSPKTVNTYRYRIFEKLSISSDVELALLAVRHGMVDASA
What is the function of this protein?
Forms part of a two-component regulatory system GacA/GacA(LemA).  May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N-acyl-L-homoserine lactone (acyl-HSL).
What are the official names of this protein?
Response regulator GacA, Global activator.
Protein: TRUB_SHESA
Sequence: MARRSKGRFIDGIVLLDKATGMSSNFALQRVKRFFNANKAGHTGALDPLATGMLPVCLGEATKFSQHLLDSDKRYLVTAKLGQRTDTSDSDGEVVQTRPLEFTEAQLMSALEHFRGDTQQVPSMYSALKYQGQPLYKYAREGIEVPREARPITVFELNFIGLEGDELTLDIHCSKGTYIRTIIDDLGEMLGCGAHVIMLRRTQVAHYPYDKMVTLEQLEALVAKAQEEQLDPSSLLDSLLLPMDTAVADFPEVNVPDASAAYLMQGQAVRVSGLVADTLVRITLGTERRFVGIGEMNQDGLLAPKRLVVLHDQAKAS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: BIOB_SHEB2
Sequence: MSQLQVRHDWKREEIEALFALPMNDLLFKAHSIHREVYDPNEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLLAMETVLTEARSAKAAGASRFCMGAAWRNPKEKDMPYLKQMVQEVKALGMETCMTLGMLSEDQANDLASAGLDYYNHNLDTSPEYYGDVITTRTYQNRLDTLTNVRASGMKVCSGGIVGMGEKATDRAGLLQQLANLPQHPDSVPINMLVKVAGTPFEKLDDLDPLEFVRTIAVARILMPLSRVRLSAGRENMSDELQAMCFFAGANSIFYGCKLLTTPNPEESDDMGLFRRLGLRPEQGAAAKLEEESAVLAKAAAYQDKSSAQFYDAGAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: S3AD_SHIFL
Sequence: MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAKRELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQDLFEALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPAQYQPVILEARQAYLGQEDRLASRADQLEEFVHYVKGEITKVVGK
What is the function of this protein?
Mediates bacterial resistance to the antibiotics streptomycin and spectinomycin.
What are the official names of this protein?
Aminoglycoside (3'') (9) adenylyltransferase, Streptomycin 3''-adenylyltransferase.
Protein: B2MG_RAT
Sequence: MARSVTVIFLVLVSLAVVLAIQKTPQIQVYSRHPPENGKPNFLNCYVSQFHPPQIEIELLKNGKKIPNIEMSDLSFSKDWSFYILAHTEFTPTETDVYACRVKHVTLKEPKTVTWDRDM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system.
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUG_SALPC
Sequence: MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLAGFTDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIEKIEDYQPAALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELDQALIMRGL
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.