Protein: TRR1_CAEBR
Sequence: MDPSIPSTSHRSVPPDRGVQPDRNLHVQELENRIQSLVHGGQRDDVKLKELQDIWASLENHFTASSHEKVVEKLVLSILQLFCNTSPQFISENNTQMLRKLMLEILLRLSNTDPVKTHSKEILKQMMRLIGVENEENAILAIRILIDQGRYGKLDYCREVQSLLLLMRTMVKELAESGRTAEMFLVRELTVPPATSSEEQLIAEYLTKCYYAQPVILNAKDGLQGPKFNMIPSAHQSIKVLLEMPFLVIFFYQNFKTTVQTEALEFTRLCLDFLNVPVPADKTKYHDVLTDDFVTVQSKILSFVNIMAKIPAFMELLQQNGDSLVSGTMQMLERCPPDLISVRREVLLAVKYFTAGEMKSRFFTMLPRLISEHFILGTGFTAIELLRVFMYQMLADLMHHTRDTISYELISHVVFVFCRALHDPNNSAQVLIMSARLLNSLAESLCRMESQAPIRDLMLEILEAQVSKLKVMAVYHIPILFQQYGTEIEYEYRNYERESEKPKVNVMKESTQREVPKRRTRKLSMDSVEELEFLVTDNVNMTESEQKRNELPTPTKEHTKKTSPEAILNSLYAASTQPLGLSETRNLIKYVMHTCKYVTGQLKISRPSTEMYHCVRERDLYERLLRYGIMCMDIYVLPAVKNQAQAHASQRTKEEKEALESLANVFTSIDHAIFRELFEKYMDFLIERIYNRNYPLQLMVNTFLVRNEVPFFASTMLSFLMSRMKMLEVSSDKTALYVKLFKIIFSAIGANNSTIYQDRMLTNYLPEILKQSTVLALTAREPTNYFLLLRSLFRSIGGGAQDMLYGTFLQLLPNLLQFLNKLTSCQHRIQMREIFVELCLTVPVRLSSLLPYLPLLMDPLVCAMNGSPNLVTQGLRTLELCVDNLQPEYLLENMLPVRGALMQGLYRVISKAPDTASMKVAFRILGKFGGANRKLLNQPQLLQVRRFPDSYLNMEFSQMGLDGNHSLHLPISELMRVAADQMRYPADQIFNPNPTNIPSPHVKKCCMELSKAVLLAGLGSSGSHTVPTKDLPKVLKKLLTGFNVNQRTTEIYICPKENDREVYVNALLVVAYGIWNKDGLRQLYSRFFVKIIRQFALMGAIEFVSGNGWMQNADEEGALPLCLDSSVLVDALITCLSETSTSFFYGGIMCLRYINETLELALPDINQMSKVPLCKYLMEKVLKLCHGPAQYARAGGINAFMYMIEHYPRKFIMDFVIDVVDAIMEVLLGLVEEISSGSADIATDCFKKMMRTYFIQEENQEEENLTLASIFVAVFGKHYFHGNDRIRDYMAQLMEYCMIQSRLETNLDKFYYRFREFFEPELIRIMETLPTMSLTDAQGSLDGLQRFVFICPEGFEFEKDSEIYKRYLVHLLDLAQTDTQTINQRNAFKKCETCPSHFLPPFPILHHIDQMRGSALQCLVIAYDRLRKQLENTTRDIEDEQLMSEILAMNSPRITVEQIFENNESWRRLMTVLLRAITDKDIPDIADKLYPALMRVTPVPTNIIATFGANYIRNISRANDENDPDRTITYHDCRKFSILVELNPKILVRNIVKNLANHIIKYNMSDSISNILVMPNEAKEEEVEAYEAEKKRGVRDLEMIGYTAKMLAGCSMEILTAEIIIDITRFAAKFEYTYSQDVLPNWIDDVVKLMNKAPVEVWKFFLLRESVANPARRSLIRRAIIFPTSEPLRKVFMQTPEYLERLIDSNLDNYDNSDERVIIDREMFLLSLVDRISRNCHDWLSDPSLSPIPQLRAFFNGTEFMDRYSVRSIMVEEAREIRVISMTEDKYKVPKLMTNIFLRYLRFVRKYFPVKLIFYRNNIQDYDMFFNVVSVFMGKFQTDFTFVREYLEVEVIPKMPLWWRREIFIKVMVMFEENAQKACKDFRILKALQYLILPSLQWAFERYDTDEIVGSAPIDDSENAADAESSNNTENLVGRLTSVIGAHRLDFSDGMIILFYQLCTLFVQHAPEHIHNNHCKKQGGRLRNFMLFAWPCLATPNRQDPTLRYTGFFFLANIIERFTINRKIVLQVFQQLMTNYQQDTRDQVRRAIDILTPALKVRMEDGHQQILTQVKKLLIEEGHILQHIQHILGTIIRNWRVYYHIRHEILTPLLNAVQRALTMPNSVIEHAQTRKQAIEVCEMIIKWELLKLHKTDHIITDDEANEVDKLYEKLRGASSPDRYDFEDQQMKKDLLDSQRVITREHVDIVVNMLMRFCVMFHTSAQNNSTSGQQGAELVKKCQLLLRICLRSSVWGDFVNIRTSILNNYIVVPSELIPKQNEVQNPEYVLAANNSQYTIEMLNVIVPILPKPTLKNVLNILQPALIGVIQSSGHMSRGITQLISRLGERTSVSTNGLDEFELLNSYIVKYIHDSFSTILRCVLIWISIYSLNPFFRNQNAPVLSVLGSFTLLRAMCGHEAGFLDNFMPTFLKVMDRVAREHLQFNSRQQPSVQKNLSELTCVCMELVRQRIDHIGLELKRTTITDVMTELIFKSTSERVIQVCAKLIGAMLSPTDMEFSLHTCLQQLVRIQSVIISKFKNCKEVITEFLVVVIKVFENAEYRNSEYGARLWEAFFWGLKSTDPTTRDSFSAVWEMTWPQMSTADICHRMKYIMKHQDWSKFKHAFWLKFALWGMLRAISKRPKSVNNPKKKVVMLNCATPWRTIEYAARLKEQHMETDPMIKLEEPEPMEVDQPKNAPAEEPKDNKLSLDDFLAGQQELLEEAAEFDFADALDTVSQITFGINDNGMTSRIWVTFFKSFWASLQPREVEDFTALIVPFLSSGVHNQFQTGVQDSVLAVWLEAIGEKVPLPSSLIEFISSKHECWYTGISILESSIWSIPKQLNNTLLGNINCDRSLTSNIETLESLGALYKELAEFDQYSAIWERRSVFPETMKAMSALQLGDMDTAASILEQAMNKEMEHLPVPTANAAPPGPNDRQISPIYDREYEQWMQMYMSSCSELLQWQTVAEISNSREVQDVRGIITAASHIPDWNLVEDCRSMLSGCIPPDFHLEYTVFNLMSTVMRLNESVNVPHARERCKQALQECIEAHISRFRALPSVTSYGHVKILQSMNLVRDIEESMEVRIALLEQPTKMDQSLMMDMKSLMKVYRNRTPTTADDMGFVATWYDWRNQIHGMMLQRFEWFDKSSLSTTGNGNQSIVPIHSMAQAQLTVAKHAKSLGFNNLAKDLLNKLGGLPAIPMMDAVDKVCTYGKTLRALSNNVDDERSKQELLYEALEVLEDVRIDDLQKDQITSLLFNRATIHSALGQTANADRAFSAAVQLTDMKTANVPTGIKLFRQWGNHLNKLFFDQSQMVSKETSENFGRQALSCYFVAARVDGDLKARKPIAKILWIAKHLMASGASEALNRVIQKHLPSLNLFNWLYWIPQLVTEISHQPNNNFIMVLCRVSLKSESFNSNGASKVSKSGISGPRKQSKVTPRFPRFLIEQNLNQCDDIAAAHPLQVFYHIREAVSVEDIDAVFAQDYTEEEMSMDTPDDEAFSNDPPFSRALKICLKYRPTDIRVLHRILKELDQMTETWVERHLRFAVAIKDQLFEDFAEQMDARFNEMQFSGAVYELTQKWKRQLEEDYKFFENNYNLDLLEIRNRRRVIVTKGYMGTVPSQIMFEKELSQVFTDPPEMKDEFEYVTEITKVIFDQLDIRSPQAPRPALFVRTVMEWIRIIRRRFDRLPRRVPMEISSPYLARFSHRTGCIEMPYDLLNVLRAKNHSLNATNQTGQYISMMSRFEPYFEIVMRGGQVTRKIYLRGQTGKSAAFYLKKSIKDERTNRVPQMFKHVDYLLQNDRETARRHLSVPSLLQMRVSKNTTFCEIASVQPYAIPQDCSRNYPASQIEVMHPYEVLTSTFNGLYSPDDMVMHFYERFADSCSSIGQPLPQNIDPSMASQPRLTEPHHVKNIIYEDFARDMIPFRLLTDYLLARYPDPVMFYAMRKQFIHSFAVLSIIEYHCNLSPMTPHQMIISMNTGVLNNPFYRFELGTGQLMDIEHFAHEVPFRLTPNLMMFVGVAQDGDLLWSMAAVARCLMKKEPGAVMRPLLWDEYANNVNYENMIYICHAANSYVKCIENKVAMTNRHDAKVKKDDCNSLIIRAKDSDNLSRMPPTYHAWF
What is the function of this protein?
Influences germ cell fate in hermaphrodites (PubMed:24098152).  Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (PubMed:24098152).  Required for spermatogenesis and embryonic development (PubMed:24098152).  Acts with tra-2 to promote expression of fog-3 and control male tail development (PubMed:24098152).  Involved in the negative regulation of vulval development (By similarity).
What are the official names of this protein?
Transcription-associated protein 1, Cbr-trr-1, TRRAP-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. TRA1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to condensed chromosomes during pachytene and diakinesis stages of meiosis I in germ cells.