PharMolix/UniProtQA huggingface dataset:
Protein: KCIP2_MOUSE
Sequence: MRGQGRKESLSDSRDLDGSYDQLTGHPPGPSKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRPLDPDSVEDEFELSTVCHRPEGLEQLQEQTKFTRRELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSNYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQQDENIMRSMQLFDNVI
What is the function of this protein?
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels.  Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:20943905, PubMed:23713033).  In vitro, modulates KCND2/Kv4. 2 and KCND3/Kv4. 3 currents.  Involved in KCND2 and KCND3 trafficking to the cell surface.  Essential for the expression of I(To) currents in the heart (PubMed:11747815, PubMed:23713033).  Required for normal protein levels of KCND2 in the heart ventricle (PubMed:23713033).
What are the official names of this protein?
Kv channel-interacting protein 2, KChIP2, A-type potassium channel modulatory protein 2, Potassium channel-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Detected on lipid rafts (By similarity).
Protein: DEGPL_HAHCH
Sequence: MKVCQKYTAVLLVWLSAVVSMRAGAVDLPDFTGLVERTSPAVVNISTVRKVGDDSAQYYFGGPEQDQIPEFFRHFFGDPYRRRGPQEAQSTGSGFIVSKDGYILTNNHVVAGADEIFVRLMDRRELTAKLIGSDEKSDLAVLKVEADDLPVLNLGKSSELKVGEWVVAIGSPFGFEYTVTAGIVSAKGRSLPNENYVPFIQTDVAINPGNSGGPLFNLEGEVVGINSQIYTRSGGFMGVSFAIPIDVALDVMNQLKDTGAVKRGWLGVLIQEVNKDLAESFNLNKPRGALVAQVMKGSPADKAGLQPGDVIVSYNGNEIGLSSELPHLVGRTSPGQKASMKVVRRGDEMDVAVEIGQLPADDNGVASVPAGQTAPQNNALNLQVRDLTDEEKESMQVAGGVMVAQVFPGPAATAGIQPNDVISSINNKDVETVAQFHEVVEKLPVGKSLPVLIIRQGNPAFIVLKLNNK
What is the function of this protein?
Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.
What are the official names of this protein?
Probable periplasmic serine endoprotease DegP-like, Protease Do.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATPE_ACTP2
Sequence: MASQFELSVVSAEKEIFNGNVVSVRVSGIDGELGVYAGHTPLLTSIKPGMVKYTLENGKEEFIYVSGGFLEVQPTIVTVLADVAIRGEELDQQRILAAKRKAEDTLSKSNNAELSAKLSREIAKLRVYEIVNSKLANRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YCIB_BRUSU
Sequence: MPPLLKLALELGPLLVFFFANARGEMLIERFPILGSIGAPIFLATALFMAATVIALAISWSMTRTLPIMPLVSGIVVLVFGALTLWLHNDTFIKMKPTIVNTLFGGILLGGLFFGKSLLGYVFDSAFRLDAEGWRKLTLRWGLFFIFLAIVNEIVWRNFSTDTWVSFKVWGIMPITIVFTLLQMPLIQKHSLTDEENTAS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_SULIL
Sequence: MANGPNYKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKIDPKGDIMVASAHSSELTKKFEWKGDENNTPSAYLTGYLAALRAVKKGVTECVADIGLHVPSKGNKVFYAIKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENLPSHFEEILNKIKSSGG
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: NCAP_RYSV
Sequence: MANDNVSDYANAAPFARFANLQNRETLNPIGNEAKEIPYNRDQYLTWLAEGKLFQIGALTDAEIVAAWTTIKTAMGNNTFSETHMRSIVKIACNLRGITPGSTPLLVTYNPPQSATWAPAPSTDAIYSGTPVAGVIIPQNTGAGGEDTETEASKARAIAFICCYLLRFIVKTEEHLTNSLGNLKLQYSRLYSAQSATLSNWNPSNTWASRVKLGFDTYLTLRATVAYNIASADALLVPENVNYGLCRMLVFQHLELSGLQLYKMAMTLIAHFKLIEPNKFLSWIYDPLSEASIDQIYKIAVNYDNVNSKTHKHWKYAKLARGQYWLNTTVKRNQFLAYILADLELKYGLAGKSDYSSPKRMKALSGMPVERMTEAETISKAVEQMYTAIESAKRVDAGAAYRLAKKLGPPRANAHSRRKEPNNSRQHRDKQPNSKQQGRDKRNKHQVLGRHSKPQAQGPPNKQQDLGPHNNKPKEASRPPQQDRQQLAQPWRLTRRQRGARGHRTQTLSGMFCKGTCQCIQ
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the nucleorhabdovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RUTC_VARPS
Sequence: MPKQAIIPAGTTTPIAPFVPGTMADGIVYVSGTLPFDKDNNVVHVGDASAQTRHVLETIQNVIATAGGTMDDVTFNMIMIKDWADYAKVNAVYAEFFPGTKPARYCIQCGLVKPDALVEIASIAHVGNKA
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: SSRP_ORITB
Sequence: MENYCKIVAQNRKAKFNYFIQDKMEAGIVLQGSELKSIRSGKVSIEDSYAAESSNEIFLYNSYIGEYKQANRFNHVPRRVRKLLLHRKEIQKIIGKLSVQGCTLVALSIYFNSKNKVKVELGLAKGKKQYDKRYAIKEQEWKKQQARIMRNKF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: OBG_GLUDA
Sequence: MKFLDQAKIYVKSGDGGDGVVAFRREKYIEFGGPDGGNGGRGGDIVFEAAGNLNTLIDFRYTQHFRARKGGNGAGSDRTGAAAAPVLIQVPVGTQIFDEDRETMLADLDQPGKRIVLCHGGDGGRGNAHFKTSTNRAPRRADKGWPGEERWIWLRLKLIADVGLVGLPNAGKSTFLSVVSAARPKIADYPFTTLHPQLGVVRLSVAEEFVIADIPGLIEGAHEGAGLGDRFLGHVERCAVLLHLVDGAAGDVVKAWRTIRHELEAYDGGLAAKPEIIALNKIDAMTPQQISSRRRALEKASGMPVVTLSGVTRQNLDDVLRLLQDRVTATREAARDAAPPQAAAGREETA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR15_CHLSC
Sequence: MVKNSFNSVIPQEENKGSVEFQVFNFTNKIRRLTSHLELHRKDYLSQRGLRGILGKRQRLLAYLSKKNRVRYQELIGQLDIREPKTREF
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLNE_PROMH
Sequence: MSANSVFQQLWDKAQCTFSTKLNELAPFSEREQQFFAFSPFATEHLRVNPHWLTEIRQTPPVSDEWQNYSSQLKQQLTHVDNEDDLMAILRQFRHQQLVRIAWSQFFQLCDTPCTLKQLSVLAETLISVAKDKLYQQCCQQWGTPCDREGKPQPLLILGMGKLGGLELNFSSDIDLIFAYPENGVTQGGRRELDNAQFFTRLGQKLIKVLDQHTMDGFVYRVDMRLRPFGESGPLVMSFAALEDYYQEQGRDWERYAMVKARVLGAEKKEYCQILRQMLRPFVYRRYIDFSVIQSLRNMKSMISREVRRRGMIDNIKLGAGGIREIEFITQVFQLIRGGREPELQSHSLLTVLNVIAKLELLSAQETSQLADSYLFLRRLENLLQSIADQQTQTLPDNLEDKARLAFAMGFDDWQMLYQQINQKMQAVSVIFTQLIGEDDENEDEEDVSEFKRLWLLGRLPDSATLFHQGLTAEDRQAICQTLQLFRQDISKRTIGPRGRDVLDALMPKLLAKVCLQPQALVILQRITPLLLGIVSRTTYLELMQESDEVLTHVVRLCAASPMIAEQLTRHPLLLDELLDPHSLYQPLPLNAYQDELRQYLLRVPEEDEEQRLEALRQFKQAQLLRIAAEDIAGVLPVMKVSDHLTYLAEAIIHAVVHQAWSYMVKRYGEPAHLAQRDGLGFAVVGYGKLGGWELGYSSDLDLVFLLDCPMNILTTGAKQIDARQFYLRLAQRIIHLFSTRTSSGVLYEVDARLRPSGESGMLVSTIQAFDEYQKNEAWTWEHQALIRARMIYGDDQLQQMFARTRHETLCLARNATVLQQEVREMRQKMVQHLAPTQSNTFDLKASSGGITDIEFIAQYLVLRFSHQYPALTRWSDNVRILELMAKYQVMSEQEAQLLTQAYVTLRNELHHLALQTLPAVVDGDCFITERQWVLSSKQKWLDE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: E4PD_SHESA
Sequence: MIRVAINGYGRIGRSILRALYESGKRQQIQIVAINELAKPEAIIHLTQYDTTHGRFQPRVKLVDDQMLIGDDVIKILHEPDPAKLPWREMDIDIVYEATGAILDRNSCEAHILAGAKQVLISHPSSADVDGTIVYGVNQDLLRAEHTVVSNASCTTNCIVPVIDVLDKHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPHMKDKFEAISVRVPTINVTAIDLSVTLDKTVDIATVNQVLELAANGRFNGILGYTDEPLVSCDFNHDPRSSIIDGTQTRVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKQS
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG189_VACCC
Sequence: MDFFKKEILDWSVYLSLHYIARVCSNSSTSHIIQDYNLIRTYEKVDKTIVDFLSRLPNLFHILEYGENILHIYSMDDANTNIIIFFLDRVLNINKNGSFIHNLRLSSSINIKEYVYQLVNNDHPDNRIRLMLENGRRTRHFLSYISDTVNIYICILINHGFYIDAEDSYGCTLLHRCIYHYKKSESESYNELIKILLNNGSDVDKKDTYGNTPFILLCKHDINNVELFEICLENANIDSVDFNRYTPLHYVSCRNKYDFVKLLISKGANVNARNKFGTTPFYCGIIHGISLIKLYLESDTELEIDNEHIVRHLIIFDAVESLDYLLSRGVIDINYRTIYNETSIYDAVSYNAYNTLVYLLNRNGDFETITTSGCTCISEAVANNNKIIMEVLLSKRPSLKIMIQSMIAITKNKQHNADLLKMCIKYTACMTDYDTLIDVQSLQQYKWYILKCFDEIDIMKRCYIKNKTVFQLVFCIKDINTLMRYGKHPSFVKCTSLDVYGSRVRNIIASIRYRQRLISLLSKKLDAGDKWSCFPNEIKYKILENFNDNELSTYLKIL
What is the function of this protein?
Contributes to viral release without involving rearrangement of host actin.
What are the official names of this protein?
Ankyrin repeat protein OPG189.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG189 protein family.
Protein: RIMM_BIFLO
Sequence: MHDDPQQLELLRVARIGRAQGLKGEVTVRLYTDDPEWRFEPDSVLYSQDGETEYIVEGSRTFKDRWILKLEGVDDRNAAEALNGVELYGEVDDAEDMLEADEWYPKDLIGLEARLVEGNGLGLPAGQVVGKVVDVVDSPAQSLLKIRLTEPVVTGQNSKGEDVVEKTALVPFVEALVPDIDLEEQYLTLDPPGGLIPGCGMI
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H42_ARATH
Sequence: MNPLTQVKNLQKINARESDLGISDEASWHAKYKNSAYVYVGGIPFDLTEGDLLAVFSQYGEIVDVNLIRDKGTGKSKGFAFLAYEDQRSTILAVDNLNGALVLGRTIKVDHCGAYKKHEEEDEETRRQNREARGVCRAFQRGECTRGDSCKFSHDEKRAANTGWGHEEDRSSKWDHDKNREGRGVCRAFQRGECTRGDSCKFSHDEKRAATTGWGHEEDRSSKWDQDKLNGAKKGGTSFGNRGDFKPDVEEKSYRGRGDGDASYGRPKERERVDREDMGPRSRDAYDMKEQKRSGRYDNAYSRRHNDEIDYVREDKGSRAQDWEKRKAESRRDRNDREEKDRDSLRREDRRR
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 42, AtC3H42.
Protein: ARO1_PNECA
Sequence: MKEIIKLSILGKDSIHIGLHLWPHITNELFTCIFSPTYVIITDSNIETLYIPSFKTYFISMAKQRSINSRLLFFTIPPGEKSKSRKTKALIEDWLLSEKCTRDTVIIAIGGGVIGDLVGYVSATFMRGVRFIQIPTTLLAMVDSSIGGKNSINTSYGKNAIGTIWQPERIFIDFTFLETLTEKEFINGIAELIKTIIIWDESEFASLENISEKIAKTVRSMSLTSNKHSKFNEIIKDLKRYIISSIKIKAHIVSIDEKEKDLRTLLNFGHSIGHAIETVLAPYILHGESISIGMVKEAELSRHLGILNPNVVSRLIKCLNTWGLPTSFKDRRFKEVILGKKHLIEDILEIMSIDKKNDSNNKKIVLLSAIGKTYEKKASSVSDDDIRTILSQNILLYGIPLNAFQKHTTITLPGSKSISNRALILASLSNGICYLKNFLHSDDTYYMLSALEKLNAAEFKWEQDGDVLVVKGKSGYLENPQMELYLGNSGTTARFLTSICTLVQPNSRENHLILTGSNRMKQRPIGPLVDALKNNGCCIEYLELENCLPLLIKPKEIGLYGGNINLSATVSSQYVSSILMCSPYAKTQVTLSLIGGKPISQPYIDMTISMMSSFGIKVTRSHSKENTYYIPKGCYTCPSEYIIEGDATSATYPLAIAAITGGSCTISNVGSASLQGDSKFSEYILKPMGCEVVQSPTTTYIKGPPKGKLKSLGSINMESMTDTFLTAAVLASVAYEESKPYVTKITGISNQRIKECNRINAMVCELKKFGIEAGELPDGIYVKALNTSNLPYSVEGINCYNDHRIAMSFSVLACISSKPTTILDKACVNKTWPYWWDILNSTFKVQMKGIEFDLNPTINSSILHHPSECTIFLIGMRGAGKTTLGQLAANFLGREFIDLDSIIEEDIKTTILEFIQKYSWDVFRRKELHFLKTLLTEKKENYIISCGGGIIETEEARDLLISYIEANGIVIHIHRNIQDIIKYLNTDKTRAPYQDNIMHVWERRKRWYNLCSSHQFHMTSTDPTEFKKNIPLNLKSSFNNFLRTITGKNNIFSLILKKKRSYFLSLAFSDLENIFSLLDIITAGCDAIEIRIDLFQKPEEIDKYPSLEYIAEKIFLLRQKTSLPLIYTLRTTNHGGSFLSSEKKLAKEYILHGAKWGFEFLDIELDIASELFKTINNSWPYTKIIASYHNIEKPISCDDFEWIQKYKEAQHYGHIIKLVGTSSSIEDNFFLEEFKSKFINKKVPSIIINTGIKGQLSRIMNTFMTPVTHPSLPSKIAPGQLSIKEINTALHIMGLLPEKKYFLFGKPIKHSQSPNIHNLGFEILGLPYKYQLFETDSISELKEILHLEEFGGASVTIPLKTNISILLDEISDHAALIGSVNTITRTYNNGQYILKGENTDWQGIIKAIKNFNKFEKSFENFSGFIIGAGGASRAAIYALLSLGISPIYLINRSKDKLNKLYHFFNTNHIIPITEYHELNNINFDIRIGISTIPTDNPIDPSVLEIAKIFFNLKRKSSEGIFLDMAYGSNTTDLTIIAKACNWKIIHGLEILLEQGSEQFLLWTETYIPYNQVKYAILGPNK
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIF1_CANGA
Sequence: MDNKRHQTSIGSELSEAQNRLSTVGMRIRQRIDRGYAYSGKNVSGMDDQVPIRDVASTIVPQFRTQVLYEQQQQPQQMHRPAMNGPAPMLVNQRTESSNLDCMQEEMLSNGKRRVF
What is the function of this protein?
Mediates the nuclear localization of the ribonucleotide reductase.
What are the official names of this protein?
Damage-regulated import facilitator 1.
What is the protein family that this protein belongs to?
Belongs to the DIF1/spd1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CLPP_CITSI
Sequence: MPIGVPKVPYRSPGDKHPSWVDIYNRLYRERLLFLGQMVESDISNQLIGIMVYLSIENETKDLYLFINSPGGWVIPGIAIYDTMQFVRPDVQTICMGLAASMGSFLLAAGASTKRLAFPHARVMIHQPIGAFYGAQTGEFILDTEELLRLREILTMVYVQRSGKPLWVVSEDMERDTFMSATEAQAHGLVDLVAVG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: SECA_ALIF1
Sequence: MFSKILTKVIGSRNDRTLRKLRKIVDQINKLEPQFESLQDEELKAKTIEFRARLEQGEDLDSLLPEAFATVREASKRLYGMRHFDVQMIGGMVLNDSQIAEMRTGEGKTLTATLPCYLNALTGKGVHVVTVNDYLAKRDAETNRELFEFLGMTVGVNVPNMPPQEKKQAYLCDILYGTNNEFGFDYLRDNMAFRAEDRVQRERYFAVVDEVDSILIDEARTPLIISGPAEDSSELYIRINTLIPQLVKQDEEDSEEYRGEGHYTLDEKGKQTHLTENGQEFVEQLLKDAGLMEEDDTLYSPANISLLHHINAALRAHVLFEKDVDYIVKDDEVIIVDEHTGRTMPGRRWSEGLHQAVEAKEGVKIQNENQTLASITFQNFFRLYDKLSGMTGTADTEAFEFQSIYGLDTVVIPTNRPMARNDMGDLVYMTEAEKFAAIIEDIKGCSERGQPVLVGTVSIEKSELLSNALKKAKIKHNVLNAKFHEQEADIVANAGTASAVTIATNMAGRGTDIVLGGSWQADVAKLSDPTEEQIQAVKAKWKEAHDAVLASGGLHIIGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMKKLGMEEGEAIEHPWVTKAIENAQRKVEGRNFDIRKQLLEYDDVANDQRKVVYELRDELMNVDDISEMIGYNRQEVLEGLFGQYIPPQSLEEMWDVEGLTIRLRADFDLDLPLQEWLDNDDKLHEDNLREKIIEAAVQVYKEKEESVGESVLRNFEKAVMLQTLDGLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFEGLLDTLKFDVVSILSKVRVQQQEDVERMEEQRRLQAEEAARRQQLQHQNAENQLDDGEGAEEAHSPMVREERKVGRNEPCPCGSGKKYKQCHGKI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: NPD_BACCZ
Sequence: MIFVQQFEEVRLILEKAKKITVLTGAGASTESGIPDFRSANGLYADANVEMYLSRGYYNRSPKEFWKHYKEIFQINTFHQYKPNRGHRFLAELEEQGKDITILTQNIDGLHQVGGSKHVIDLHGTLQTAHCPKCKTGYDLQYMIDHEVPRCQKCNFILNPDVVLYGDTLPQYQNAVKRLYETDVLIVMGTSLKVQPVASFPEIAKREVGATTVLVNEELTGQEYNFDYVFQNKIGEFVEGLSSRK
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAF1A_CHICK
Sequence: MAAMECRDKAVVPPRRLVQARLPFKRLNPVPKEKHDAEAEGKKGKCSKSGLGQSKDSSTDTLHASTDNMENDCQLNSDVNFVPKLVNGKGPLDHFIQKSTKDNTDEIIVIIDSVDESNQRLSDDVDHVSFDSKASSAALTNGMLGKDMNKLSCLNSTQNSQTDDSMQTDVPCEAIANKGEDLVDGIQSCSGLTERNNLENTKVNQSELKDVIFEGKMPVVLLEDIMAAKSPQVTSLDGSVTSENETVELSHEGDSVLTNSSLSSLSVSSPEAQPVAETKRNTSPLAVSTPVRKVSQKLHKSSAEKEKLRLQRDQERADKLQKLQAEREEKGRLKEEAKAAKERAKEEAKKKKEEEKELKERERREKKEKEEKEKAEKLRVKEEKRKERQEALEAKLEEKRKKEEEKRLKEEEKRINAQKAEITRFFQKPKTPQAPKILAGSCGKFAPFEIKENMVLAPLCRIALYPDFLEQLDRLLRAQNSEVSFLRDLKCRKPRKTGPTFVNSSTDTVNSDVVVVDNCKTDAVPERGKFGRMKLLQFCENHRPAYWGTWNKKTTMIRPRNPWSKDSKLLDYEVDSDEEWEEEEPGESLSHSEGDDEEEGEDEDDDDGFFIPHGYLSEDEGVTEECDPENQKVRQKLKAKEWDELMAKGKRLHVLQPVKIGCIWESAQNDSGTNADLKILQQFTACILDSSVAEEEQQIQKCSKKRAKDQQILGQLLPLLHGNVNGSKVIIQEFQECCRQGLFSDVTAATDCGDTSPVSPNTSRPQTPVGEDSGVPSKARLKRIISENSVYEKRPEYRMCWYVHSEVLKSFDQEHLPVPCQWNYITQVPSSGKEDGGSVPGVAPVQSTPVSVKRKSTGSMCITKFMKRPRDAEQAEAMEMDGFQADTEEDEDDDDCMIVDVQPCKDSTLTVTETAPESRGTTAAHQDASMVSPSNTV
What is the function of this protein?
Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair.  Assembles histone octamers onto replicating DNA in vitro.  CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.
What are the official names of this protein?
Chromatin assembly factor 1 subunit A, CAF-1 subunit A, Chromatin assembly factor I p150 subunit, CAF-I 150 kDa subunit, CAF-I p150.
What is the protein family that this protein belongs to?
Belongs to the CHAF1A family.
What are the subcellular locations of this protein?
Nucleus. Note=DNA replication foci.
Protein: RL11_BRUO2
Sequence: MAKKVAGQLKLQIPAGAANPSPPIGPALGQRGINIMEFCKAFNAASQEMEKGSPIPVLITYYQDKSFTFVMKTPPVTYFLKKAANLKSGSKTPGKASAGTITRDKVRAIAEAKMKDLNAADVEAAMRMIEGSARSMGLEVVG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SECD_THEGJ
Sequence: MARKKGVKALLLNWRVLLLILFLIGSVVSMSIKGLTYGIDIGGGVALIAEPEKPVSKDTLNGIITSLQNRLNTFGVKDITIEAQHDPETGQSLIVVKIANVTLDEANQIKDLIESQGVLYMEFNGVIFATGTDVTVHSSDYGLDLQECPTCWYVGFELSGKAQNKFKKIAAGKLGWPIDIYLDPPVNSLLVVSPRVYQEMNSGDFMGAPSEGTPKPLVERLKEAFNITVVEYSNQTAEDIVENATALGKDKIILADVPEELYNDVRELVLSKDLKLRVSHYTPQQGEDLKDFVKRILNLYGPYVLKFDPAKGETTRLKLSGSAPTKEEALQEARKIYSVLRSGSLAVKLHVVSEEYISPTLGASFKKQAIIAGIGALIAVLLIVYFHYRRWRIAIPVASTSLFEVIIILGIAALIRWNLDLPSIAGIIAAIGTGVDQQIVITDELLGGTAGRVTRRMSALRRMARAFFIIFASAATTIVAMSFLLVYFVGTLKGFAVTTILGVLIGVLVTRPAYAEIAKYLLSLE
What is the function of this protein?
Involved in protein export.
What are the official names of this protein?
Protein-export membrane protein SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NANR_ENT38
Sequence: MKPIDLQAENSTETVGRSLRRRPLARKKLSDMVEEELEQMIRRQEFAQGEQLPSERELMEFFNVGRPSVREALAALKRKGLVQINNGERARVSMPSADTIIGELSGMAKDFLTQPGGITHFEQLRLFFESSLVRYAAEFATDEQVESLSKALEINSQSLSDNALFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPKVSDAELYEHNNVSYRQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQGSKKKK
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.