PharMolix/UniProtQA huggingface dataset:
Protein: RL14_SYNSC
Sequence: MIQQESYLTVADNSGAKRIQCIRVLGTNRRYAHVGDVIVAAVKDAAPNMGVKKSDVVKAVVVRTKATMRRETGNSIRFDDNAAVIINDDKNPKGTRVFGPVARELRERSFTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HVM23_MOUSE
Sequence: EVKLVESGGGLVQPGGSLRLSCATSGFTFSDFYMEWVRQPPGKRLEWIAASRNKAFDYTTEYSASVKGRFIVSRDTSQSILYLQMNALRAEDTAIYYCARDYYGSRYWYFDVWGAGTTVTVSS
What are the official names of this protein?
Ig heavy chain V region HPCG8.
Protein: KAD_BACCN
Sequence: MNLILMGLPGAGKGTQAEQIVAKYNIPHISTGDMFRAAMKAETELGLQAKSFIDKGALVPDEVTIGIVRERLSQEDCKKGFLLDGFPRTVAQASALEEIMKDLGKKIDYVLNINVDSGLLLKRLTGRRICKECGATYHLEFNPPAKADVCDKCGGELYQRSDDNEETVANRLEVNIKQTKPLLDFYEELGYLQSINGEQDINKVFADIDVLIGGLA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_STRPI
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RS17_ARCFU
Sequence: MRDIGIDVKPPERECEDENCPFHGTLSVRGQLLRGKVVKVYGKTAVIERELIRYVPKFERYMKKRSKLHAHNPRCIRARPGDIVTIGECRPISKTKSFVILEVVGNEGNKS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NTCP7_XENTR
Sequence: MGLLERLRKEWFIVGIILVIAAAKLEPTIGGKGGPLKPEITITYIAVSAIFFNSGLSLKTEELTNALMHVKLHLFVQLFTLVFFPTAIWVFLQVLSLTPINEWLLKGLQTVSCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPLLLLLFLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERKKPPFGAISSCVLLMIIYTTFCDTFSNPNIDLDTFSLVIIVFIIFFIQLAFMLLTFLFSTSKNTGFTPADTVAIVFCSTHKSLTLGIPMLKIVFAGYEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMLSRQKALKLTRQPKVPL
What is the function of this protein?
Involved in teeth and skeletal development.  Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix.  Required for extracellular matrix mineralization.  Also involved in the regulation of cellular calcium homeostasis.  Does not show transport activity towards bile acids or steroid sulfates.
What are the official names of this protein?
Sodium/bile acid cotransporter 7, Na(+)/bile acid cotransporter 7, Solute carrier family 10 member 7.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane.
Protein: GCSH_SHELP
Sequence: MSNIPTELKYASSHEWIRREEDGSYTVGISEHAQELLGDMVFVELPEVGDSVSAGDDCAVAESVKAASDIYAPVSGEVVAVNEALEDSPELVNSDAYGDGWFFRIMPSDLSELDNLLDAEGYQAVIDEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: CRR58_ARATH
Sequence: METTKKLFALLCLFVTMNQAISVSDPDDMETFCMKSSRNTTSNTTYNKNLNTLLSTLSNQSSFANYYNLTTGLASDTVHGMFLCTGDVNRTTCNACVKNATIEIAKNCTNHREAIIYNVDCMVRYSDKFFLTTLETNPSYWWSSNDLIPKSFGKFGQRLSDKMGEVIVRSSLLSSSFTPYYLMDTTRFDNLYDLESIVQCTPDLDPRNCTTCLKLALQELTECCGNQVWAFIYTPNCMVSFDTYNSSLPPLPPPSRSGSFSHRGNNKLLGGMVLAVSVSVFAFLSLV
What are the official names of this protein?
Cysteine-rich repeat secretory protein 58.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RPPH_SHEPC
Sequence: MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGLRPEHVHILTSTRSWLRYRLPKRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAATALSFQTQEIPRKRGRQKTTG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: C3H53_ORYSJ
Sequence: MDAYEATKVVFSRIQALDPDHAAKIMGFLLIQDHGEKEMIRLAFGPEALLHTVMAKARKELGLLPASGPGTPTSVAAAAAAAHSPFMLSRQNSGRCGTAPSPLSVSSPSSWAPPPVFSRNNSISNGAGEEMVGLGDELISPANGGGPPSPFFGGDPLMDELQLQDQLAFLNEGGVPAGHQMPMFDGGECRSPGGGDGGLFSYNLGWANGGPGHRRSASVSELCLGGADGLGWKPCLYYARGYCKNGSACRFVHGGLPDDAAGKMDPSAVEQQCQDFLIRSKSQRLAAAAFPYSPTGSLPGSPSAATKCLSLLLQQQQQQNESQRAAAAAALMLGGDEAHKFMGRPRLERADFASMMNPGSRQIYLTFPADSTFREEDVSNYFSIYGPVHDVRIPYQQKRMFGFVTFVYPETVKLILAKGNPHFICDARVLVKPYKEKGKVPDKYRKQHQPGERVDFSSCTTPTGLDARDPFDMHQLGARMLQHSNSANEMLLRRKLEEQQQAAELQQAIELHSRRLMGLQLLDFKSRAAAAPTPIGNPFSASQTAANATGESPPDSGELGKGSGFLLAHKKAVNGADKEESTGESSSPNTDSDQSVEHNLPDSPFASPTKSAGFARDPFAPTEAEISATASTGCSATYVGINNGASNGGTNHLLPSALDMPSPKPYFFPMSRLASDHGAIGM
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 53, OsC3H53.
Protein: CH60_SHISS
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGP3_ARATH
Sequence: MVVIEQKKRFALFLATCDSEFVKKTYGGYFNVFVSTFGEEGEQWDLFRVIDGQFPDENDLDKYDGFVISGSPHDAFGDADWIVKLCEVCQKLDHMKKKVLGICFGHQIITRVKGGKIGRALKGADMGLRSITIAKDNEKLRGYFGDVEVPASLAIIKCHQDEVLELPESATLLASSEVCNVEMFSIGDHFFCIQGHPEYNKEILFEIVDRVLNMKLMEQEFADKAKSTMETAQPDRILWQKLCKNFLKG
What is the function of this protein?
Involved in glucosinolate biosynthesis.  Hydrolyzes the gamma-glutamyl peptide bond of several glutathione (GSH) conjugates to produce Cys-Gly conjugates related to glucosinolates.  The gamma-Glu-Cys-Gly-GSH conjugates are the sulfur-donating molecule in glucosinolate biosynthesis.  Can use the GSH conjugate of the camalexin intermediate IAN (GS-IAN) as substrate.  Required for the biosynthesis of camalexin, a pathogen-inducible phytoalexin with antibacterial and antifungal properties.
What are the official names of this protein?
Gamma-glutamyl peptidase 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C26 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MLO3_ARATH
Sequence: MTDKEESNHSSEVGAVRSLQETPTWALATVCFFFIAVSICLERLINLLSTRLKKNRKTSLLEAVEKLKSVLMVLGFMSLMLNVTEGEVSKICIPIKYANRMLPCRKTIKSHNDVSEDDDDDDGDNHDNSFFHQCSSKGKTSLISEEGLTQLSYFFFVLACMHILCNLAILLLGMAKMRKWNSWEKETQTVEYLAANDPNRFRITRDTTFARRHLSSWTETSFQLWIKCFFRQFYNSVAKVDYLTLRHGFIFAHVSSNNAFNFQNYIQRSLHEDFKTVVGISPLMWLTVVIFMLLDVSGWRVYFYMSFVPLIIVLVIGTKLEMIVAKMAVTIKENNSVIRGTPLVESNDTHFWFSNPRFLLSILHYTLFLNTFEMAFIVWITWQFGINSCYHDNQGIIITRLVLAVTVQFLSSYITLPLYAIVTQMGSSYKRAILEEQLANVLRHWQGMVRDKKKTIQTPDTDNNSNNNNGDIDSGESPVQTEVASEFRFSGRQSPILQEIQIQEKTER
What is the function of this protein?
May be involved in modulation of pathogen defense and leaf cell death.  Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity).
What are the official names of this protein?
MLO-like protein 3, AtMlo3.
What is the protein family that this protein belongs to?
Belongs to the MLO family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DENR_PICST
Sequence: MTEVVAREVYYCGVCSFPPEYCEFGVSLKRCKDWLQDNNQELFDKIYSDDALATQTSTLSIERQEKISQELAKKQLKEEAKQERELQKKLASKVLIKRIERNRRKHIISISGLEVFNIDMKKLAKTFASKFATGASVTKTADKKEEILVQGDVSDEAKEYIEKLLEEQGLNGVEVEQVDEKKKKKATAPGATPAA
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXA1A_SCOAL
Sequence: MNKLTIIFFTILLLTYIIVEKEALKIEDLPEPESYKKAKQLAVKDANGDKRAEGIALDFLRQNRRNCTVNCDLVLTCPLLTPECCPKKNDDCLKLDTVKNG
What are the official names of this protein?
U-scoloptoxin(10)-Sa1a, U-SLPTX(10)-Sa1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNZ_LISMC
Sequence: MELVFLGTGAGVPSRGRNVTSIALSMLNERNTIWLFDCGEATQHQIMRSQIKLSKLEKIFITHMHGDHIFGLPGLLSSRSFQGGDSNLTIYGPAGIAEYVETSLRLSGTRLTYKINFEEIEPGLIFEDEMFLVTADDLDHGVRSFGYRIVEKDKQGALNAEKLKADGVEAGPVFQKLKNGEIVTLADGRVIDGKNYIGEPQKGKIISIFGDTKETANELELALNADILVHEATFEGDKAKMAGEYMHSTTLQAANLAKTANVKKLILTHISSRYDRDASKELLIEAKTIFENTEIAYDLAVFPIGE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: HBB_COLGU
Sequence: LGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL21_BUCA5
Sequence: MYAVFISGGKQYRVVKNQIIRLEKLNSPLGTTIEFDKILMLFDKDSIKIGTPFVEGGTIKAHIQNHGRLKKIKIIKFNRRKHYKKQQGHRQYFTDVKIIDINSIKGEV
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL7_RHORT
Sequence: MADLAKLVDELSALTVLEAAELSKLLEEKWGVSAAAPVAVAAVAAEAAAPVEEKTEFDVILVDAGDKKINVIKEVRAITNLGLKEAKDLVEGAPKPVKEAVSKDEAASIKKKLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RASP_GEOKA
Sequence: MVETLESIISFIVVFGALVFFHELGHLLLAKRAGILCREFAIGFGPKVFSFKKNETVYTIRLLPLGGFVRMAGEDPETIELKRGQVVGLLLDESGQVEKIVLNHKDDYPNIRVVEVEEADLEHGMYVTGYTDGERFERFTVKEPAFFVVDRQEIQIAPYHRQFAAKTLGQRTMTILAGPLANFLLSLVVFIIIGLLQGYPVDKPVIGELTPEGAARAAGLKQGDKVIAINGERMETWTEIVNTIRAHPGEPLQFQIERNGKERSVTVTPEAKTVQGETIGLIGVYQPMEKSVLGSIKQGLVETYYWTREIVTGLGQLITGQFQLDMLSGPVGIAVSTGKVAESGIYYLMKWGAILSINLGIVNLLPLPALDGGRLLFFAIEAVRGKPVDRQKEGMVHFIGFALLMLLMLVVTWNDIQKFFL
What is the function of this protein?
Is responsible for Site-2 cleavage of the RsiW anti-sigma factor.  This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
What are the official names of this protein?
Zinc metalloprotease RasP, Regulating alternative sigma factor protease, Regulating anti-sigma-W factor activity protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASSY_LEPIC
Sequence: MAQNKPVKKIVLAYSGGLDTSVILTWLKDTYGCEVIAFTADIGQKEELSGLEEKGIKTGASKVYIQDLRLEFARDFIFPAIQGNAIYEMRYLLGTSLARPLIAKAMVEVAEKEGADAFAHGATGKGNDQVRFELGVKSLAPEKTIIAPWRIWSFGGRSDLIEYAKSKGIPVPVTAEKPYSMDRNLMHISYEGGILEDPYKEPDEKMFLLTTSPEKAPDAPEYLELDFEEGNCVAINGKKMNPLEIMETLNTIAGKHGVGRVDIVENRLVGIKSRGVYETPGGTILFLAHRDLESITIDRDTQHHKDKLSIEFAELIYNGHWFSSRMKAVRAFITETQRYVSGTVRIKLYKGICSVVGRKSQVSLYNPEMATFEKEELYNQKDAEGFINIYGLPAQETARLRKK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHB_DROME
Sequence: MLATEARQILSRVGSLVARNQMRAISNGTAQLEQQAQPKEAQEPQIKKFEIYRWNPDNAGEKPYMQTYEVDLRECGPMVLDALIKIKNEMDPTLTFRRSCREGICGSCAMNIGGTNTLACISKIDINTSKSLKVYPLPHMYVVRDLVPDMNNFYEQYRNIQPWLQRKNEAGEKKGKAQYLQSVEDRSKLDGLYECILCACCSTSCPSYWWNAEKYLGPAVLMQAYRWIIDSRDENSAERLNKLKDPFSVYRCHTIMNCTRTCPKGLNPGRAIAEIKKLLSGLASKPAPKLETAALHK
What is the function of this protein?
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL34_SHESW
Sequence: MSKRTFQPSNLKRKRSHGFRARMATVGGRKVLARRRAKGRARLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GAK1B_RAT
Sequence: MTCPDKLGQLINWFVCSLCAPRVCKLWSSRRPRTRRNLLLGTACAIYLGFLVSQVGKGSFQHGQATNRGPPNNQDIFKVPFPEIPLDGTLAPPESQGNGSTLQPNVVYITLRSKRSKPANIRGTVKPKRRKKYAVASVAPDQEVLVRPSLIQPEVARAADAEVPGYVQGYLTKVGERPWRMLHGPRVRGSNLQQPRAPESNIRIYSESAPSWLSKEDIRRMRLLADGEVASILPTIFEGGTRLLMLEGSTSGSVPGCGPSPCGLLKQPLDMSEVFAFHLDRILGLNRTLPSVSRKLEFIQDGRPRPIILWDSSLVPSSNVSHSSVKITWGTYQQLLKQKCWLNGRVPRPEWGCTEVHHHEWSKMALFDFLLQIYNRLDTNCCGFRPRKEDACVQNGLRPNCEDQSSVTLAHIIQRKNDPRHLVFINNKGFFDRSEDNLNFKLLEGIREFPESAVSVLKSQHLRQKLLQSLFLDQVYWESQGGRQGIEKLIDVIERRARILITYINAHGARVLPMNE
What are the official names of this protein?
Golgi-associated kinase 1B, Expressed in nerve and epithelium during development, Protein Fam198b.
What is the protein family that this protein belongs to?
Belongs to the GASK family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: OMP10_RHILO
Sequence: MTIARKVLSIGMAGSFAMMLAACTTSGPDAPPMAAAPKGVEGSWIDAKGTGLSTFTAGKFATVATDTGQKLADGSYTMTGATSVEINGTSLIRQTPVSFNCLLISTSQLNCTSSSGQNFVLTRRT
What are the official names of this protein?
Outer membrane lipoprotein omp10 homolog.
What is the protein family that this protein belongs to?
Belongs to the rhizobiaceae omp10 lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DSBB_NITEC
Sequence: MRIIFLLIFLACAGLIGYALYLQLMDGLLPCPLCIFQRIAYWLIGITALFTFIHNPQSLGQHIYYGLIILFSLAGAIVAGRQAWLIRFPEAFECGISPEEAFLNGLPLAQWWPNMFEANGDCNDGTWQFLSLTLPDWSLLIFAAFGIIAGLLWHKKYNSINQ
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVB_BURP0
Sequence: MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYAEVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: P5CR2_DICDI
Sequence: MVATDLKNNKNIAILGSGNLGVSIARGIVASGHYKSNQIVLTRRTLEKIQHLKDEEGFQITSDNLEAANKCAILIIGVLPAQVPQLLESIKHLVTKDHIIISVVLGITISGIRSHLQPDVYTPIVRAMPNTAIQYCESMTCIANKSDHPTKSGTAEQELADQNALEVTEKIFNCCGECITISEEAMVSAPALCSCGTAFFCRIIRAAASAGCEIGFHAEDAVRIAAQTAKGAAIMLLKNDSHPESEIDRITTPSGATIAGLNTMEHNGLSSAIIKGIVMSAEKSSKSQAALNKLNNVSS
What are the official names of this protein?
Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
Protein: IOVO_COLMD
Sequence: IVTVDCSDYPKPVCTLDYMPLCGSDNKTYSNKCNFCNAVVDSNGTITLSHFGRC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSG_ECO24
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMSERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: CINA_THEPX
Sequence: MRGEIISVGTELLLGQILNTNAKYLSEKLALLGIDIYFHTNVGDNEERLKECLNIAFNRSDLIITTGGLGPTVDDITKETVASFLGLPLVENLEAKEEIIRFFEKIGQTPTMNNFKQAFFPEGAKILPNKNGTAPGCIIEKDNKIIIILPGPPSELIPMFEEYVYHYLKSKTNETIKSRVIKIFGLGESKVEEMVRPLLFNSNPTVAPLVGDGYVILRITAKGHDDKEISEMIEDMESRIRGIIGDYIYAVDEEEMEEVVVKLLQKNKLTLAVSESCTGGLLAKKITDVSGASKVFNLGVVSYSNEAKENILGVRKSTLESYGAVSYETAKEMAENVRKLANADFGLSTTGIAGPTGGTPEKPVGLVYVGFATNEEVYVKKLMLSGDRSKIRTRTVLHALDIVRRYLLGIKID
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RL332_MYXXD
Sequence: MPKGNRTIIHLVSSAGTGYVYTTTKNKRKSQEKLQLRKYDPRVRKHVLFVEGKP
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: YNBB_BACSU
Sequence: MFDTLTHGELLKKTAMEVEADIAGIHKQIEEISERNEWRVLQSYRKHKVSDTHFTPSTGYGYDDIGRDTLESIYADVFGGEAGLVRPQIISGTHAISIALFGVLRPGDELLYITGKPYDTLEEIVGVRGGENAGSLKDFQIGYNAVDLTKDGKIDYDAVAAAINPKTKVIGIQRSKGYANRPSFLISEIKEMIRFVKEINENLIVFVDNCYGEFVEELEPCHVGADLMAGSLIKNPGGGLAKTGGYLVGKAKWIEACSYRMTSPGIGREAGASLYSLQEMYQGFFLAPHVVSQSLKGAVFTARFLEKLGFTSNPKWDAKRTDLIQSVEFSDREKMIAFCQAIQFASPINAHVTPYPAYMPGYEDDVIMAAGTFIQGASIELSADGPIRPPYVAYVQGGLTYSHVKNAICSAVDSLMQKQLI
What are the official names of this protein?
Uncharacterized protein YnbB.
Protein: YSZA_BACSU
Sequence: MKKRFSSYSLPPWVRQIRLVSAQVIIPITIFQGIRTIFFPTTFDVLLLAILIFLACALHLEWI
What are the official names of this protein?
Uncharacterized membrane protein YszA.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.