PharMolix/UniProtQA huggingface dataset:
Protein: SECA_CERS5
Sequence: MLGLGTLARKIFGTPNDRKVKSVRSLVARINELETEFQALSDEGIKQKTAEFQRRVQEGGESLDDLLPEAFANCREGARRALGLRAFDVQLMGGIFLHQGNIAEMKTGEGKTLVATFPAYLNALAGKGVHVVTVNDYLAKRDSEWMGKVYAQLGLTTGVVYPFQSEEEKKAAYRADITYATNNELGFDYLRDNMKASKEEMKQRGHFFAIVDEVDSILIDEARTPLIISGPSQDRSDLYTKVDKLIPELVEEHYKLDEKTRNVTFTEEGNEFLETRLHETGLLPEGQSLYDPESTTIVHHVNQGLRAHKLFHRDQQYIVRNDEIMLIDEFTGRMMRGRRLSDGLHQAIEAKEGVSIQPENVTLASVTFQNYFRLYDKLGGMTGTAATEAEEFMEIYGLGVVEVPTNRPVARTDEHDAVYRTAREKNDGIVASIKEAHERGQPILVGTTSIDKSEALSELLKAAGIPHNVLNARQHEQEAQIVADAGKPGAVTIATNMAGRGTDIQLGGNVEMKVMQALAADPTAHPDEIRARIEAEHAEEKQKVIDAGGLFVLGTERHESRRIDNQLRGRSGRQGDPGRSAFFLSLEDDLMRIFGSDRLDKVLSTLGMKDGEAIVHPWVNKSLEKAQAKVEARNFDIRKQLLKFDDVMNDQRKAIFSQRLEIMEAEDLSDIAQDMRYQVIDDLIDMHMPPKSYSDQWDIEGMHRAVMDKLGLDAPLAKWAQEEGVDQDVVRERLCEAADRQIADKTAAFGPETMRSIEKQILLQAIDAKWREHLLTLEHLRSVVGFRGYAQRDPLSEYKTEAFALFESMLNSLRQDVTQKLAQVRPLSEEEQQAVMRQFLDQQRTAAEAPASVPQPQAAVAPQPAPELVGADNGESQPQAWGDVARNDPCPCGSGLKYKHCHGRLD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RNH2_FUSNN
Sequence: MLMEEIMDNPLYLYDLEYKNVIGVDEAGRGPLAGPVVAAAVILKEYTEELDEINDSKKLTEKKREKLYDIIMKNFDVAVGISTVEEIDKLNILNADFLAMRRALKDLKSLKNEKEYTVLVDGNLKIKEYIGKQLPIVKGDAKSLSIAAASIIAKVTRDRLMKDLANIYPDYSFEKHKGYGTKTHIEAIKDKGAIEGVHRKVFLRKILETEEEKTK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_MYCSK
Sequence: MANIKSQEKRIRTNERRRLRNQSVKSSLRTAVRGFREALDAGDKDKAAELLVATSRKLDKAASKGVIHKNQAANKKSALSVALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ALP1_ARATH
Sequence: MAPVKQKKKNKKKPLDKAKKLAKNKEKKRVNAVPLDPEAIDCDWWDTFWLRNSSPSVPSDEDYAFKHFFRASKTTFSYICSLVREDLISRPPSGLINIEGRLLSVEKQVAIALRRLASGDSQVSVGAAFGVGQSTVSQVTWRFIEALEERAKHHLRWPDSDRIEEIKSKFEEMYGLPNCCGAIDTTHIIMTLPAVQASDDWCDQEKNYSMFLQGVFDHEMRFLNMVTGWPGGMTVSKLLKFSGFFKLCENAQILDGNPKTLSQGAQIREYVVGGISYPLLPWLITPHDSDHPSDSMVAFNERHEKVRSVAATAFQQLKGSWRILSKVMWRPDRRKLPSIILVCCLLHNIIIDCGDYLQEDVPLSGHHDSGYADRYCKQTEPLGSELRGCLTEHLLR
What is the function of this protein?
Transposase-derived protein that may have nuclease activity (Probable).  Antagonist of polycomb-group (PcG) protein-mediated chromatin silencing, probably by preventing the association of POLYCOMB REPRESSIVE COMPLEX 2 (PRC2) with its accessory components.  Needed for full reactivation of several floral homeotic genes that are repressed by PcG (PubMed:26642436).
What are the official names of this protein?
Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1.
What is the protein family that this protein belongs to?
Belongs to the HARBI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNZ_SULIY
Sequence: MIQIFFLGTGAGSPSKKRKLPAFLVRREGLNILLDCGEGTQYTLMNNKLGINSIKIIGITHMHGDHVFGLLGVIASMGLLDRKETLYILGPRDLKDFLYTSFEYSKFNPSFKIEFIDNYNDQNITIATFKTCHTVESQGYLISERDRVKIDEEKLEKEKIKDWRVMRKLKEGKTVEYNGKFLKPEDYLVIKRGLKVAYTGDTIPCQSVIESVKGVDLLIHDSTFLNEPSAFTYGHSNVADAAKVALEASVKLLALTHISPRYEDVTEHLKVARRIFPKSILPDDLSYITLK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: PG024_MONPV
Sequence: MSSKGGSSGGMWSVFIHGHDGSNKGSKTYTSSGSGMWGGGSSSGVKSGVNGGVNGGVKSGTGKI
What are the official names of this protein?
OPG024 protein.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG024 family.
Protein: CLPP_PHAVU
Sequence: MPIGVPRVPFRTPGDRDASWVDILINRLYRERLLFLGQDVDSEISNQLISLMIYLSIEKENKDLYLFINSPGGWVIPGIALYDTMQFVQPDVQTVCLGLAASMGSFLLAGGTITKRLAFPHAMIHQPASSFYEAQAGEFILEAEELLKMRETITRVYVQRTGKSLWVISEDMERDVFMSAAEAQAHGIVDLVAVE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: IOVO_CASCA
Sequence: FATVDCSEYPKPVCSPEYMPLCGSDSKTYNNKCDFCSAVVESNGTLTLGHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: RNT_XANC8
Sequence: MPMNEPVDLQPSPSLLPMSRRFRGYLPVVVDVETGGFDWNKHALLEIACVPIEMDAQGHFFPGETASAHLVPAPGLEIDPKSLEITGIVLDHPFRFAKQEKDALDHVFAPVRAAVKKYGCQRAILVGHNAHFDLNFLNAAVARVGHKRNPFHPFSVFDTVTLAGVAYGQTVLARAAQAAGLDWNSADAHSAVYDTEQTARLFCKIANAWPGPASAG
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: KCC1D_MOUSE
Sequence: MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALSKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRRLQLGSSLDSSNASVSSNLSLASQKDCLAPSTLCSFLSSSSGVAGVGAERRPRPTTVTTGHTGSK
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons.  In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst.  Activates the transcription factor CREB1 in hippocampal neuron nuclei.  May play a role in apoptosis of erythroleukemia cells.  In vitro, phosphorylates transcription factor CREM isoform Beta (By similarity).  Isoform 1 but not isoform 2 activates CREB1.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type 1D, CaM kinase I delta, CaM-KI delta, CaMKI delta, CaM kinase ID, CaMKI-like protein kinase, CKLiK, mCKLiK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear upon activation.
Protein: NEUL2_HUMAN
Sequence: MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNVLPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRLVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE
What is the function of this protein?
Plays an important role in the process of myofiber differentiation and maturation.  Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins.  Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme.  During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).
What are the official names of this protein?
Neuralized-like protein 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCBF_ECOLI
Sequence: MTNTWNRLALLIFAVLSLLVAGELQAGVVVGGTRFIFPADRESISILLTNTSQESWLINSKINRPTRWAGGEASTVPAPLLAAPPLILLKPGTTGTLRLLRTESDILPVDRETLFELSIASVPSGKVENQSVKVAMRSVFKLFWRPEGLPGDPLEAYQQLRWTRNSQGVQLTNPTPYYINLIQVSVNGKALSNVGVVPPKSQRQTSWCQAIAPCHVAWRAINDYGGLSAKKEQNLP
What is the function of this protein?
Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces.  Could be required for the biogenesis of fimbriae.
What are the official names of this protein?
Uncharacterized fimbrial chaperone YcbF.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PTK2_YEAST
Sequence: MAGNGKDKEVDKSPSVSTLKLLGKRLFNSSSHTDNSSLLLSAEQLGNGRSLRKRPTSPSISGSGSGGNSPSSSAGARQRSASLHRRKNNASVGFSNGSVSSHKSSVALQDLIKHNNNPYLNSPSDILGTGTGIASTRDRDRAVLDREKEKERARNKERNTHHAGLPQRSNSMASHHFPNENIVYNPYGISPNHARPDTAFADTLNTNKENDLSFYMHDGNSKIRMLPLPIANPNDFLPEDMKQYSVHLTDNFVFDTDNKPIGSGGSSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLLKVPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNTDARFREFEVSYDNFINHQNPHFRDKGCHKPGPGSEYSLARNFKNTDATRIAWRLADPNPATRYTMDDLFNDPFFQQIETCVEPNDDDLVRVPELRKSTSTNDFSENSLDAPHDQEVIHTSNPFLKKETLTSKPRSMLEIAESPSLKQKSKVKDSAKTKTHDVGDEGGNESTKPKQQDKKENLKKDEVKNGDKDKVIEEATTTNVDSILEKPTPTSTKVEDNLSEDDSTMKELKSMLNSTPTTPTHNGPTPLPAKAGTQLDKRMSDLSLKSETPASTKNFSAPNVSSSSNSLRSLGSPSVSSSKKKKVIHHHLDITNSVTNMSSVSAFISR
What is the function of this protein?
Essential determinant for high-affinity spermidine transport.  Required for the activation of the plasma membrane proton pump PMA1 via phosphorylation of 'Ser-899'.
What are the official names of this protein?
Serine/threonine-protein kinase PTK2/STK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PORTL_BPHC1
Sequence: MKTNVKTDNKKGIVIAPINDRTFSLSEITASPALDYVGIGFDENYNCYLPPVNRHALAKLPHQNAQHGGILHSRANMVSATYEGGKALSKMEMRALCLNLIQFGDVGLLKVRNGFGQVVRLVPLSSLYLRVHKDGGYSYLMKKSLYDTAQEIYRYDAKDIIFIKLYDPMQQVYGSPDYVGGIQSALLNSDATVFRRRYFSNGAHMGFILYSTDPDLTEEMEEEIARKISESKGVGNFRSMFVNIAGGHPDGLKVIPIGDTGTKDEFANIKNISAQDVLTAHRFPAGLSGIIPTNTGGLGDPLKYREVYHYDEVMPLQEIIAETINQDPEIKNLLKIKFREQNFAK
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.  Binds to the terminase subunits to form the packaging machine.
What are the official names of this protein?
Probable portal protein, ORF15.
What is the protein family that this protein belongs to?
Belongs to the phage portal family. PBSX subfamily.
What are the subcellular locations of this protein?
Virion.
Protein: CDN11_RANXA
Sequence: GLLDGLLGTLGL
What is the function of this protein?
Caeridins show neither neuropeptide activity nor antibiotic activity.
What are the official names of this protein?
Caeridin-1.1/1.2/1.3.
What are the subcellular locations of this protein?
Secreted.
Protein: RL11_TOXCA
Sequence: MGDVEKQTEIREKKARNVMRELKIQKLCLNICVGEFGDRLTRAAKVLEQLTGQTPVFSKARYTVRTFGIRRNEKIAVHCTVRGPKAEEILEKGLKVKEYELYKENFSDTGNFGLGVQEHIDLGIK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SPR1A_HUMAN
Sequence: MNSQQQKQPCTPPPQPQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCHPKVPEPCQPKVPEPCQPKVPEPCPSTVTPAPAQQKTKQK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.  All that results in the formation of an insoluble envelope beneath the plasma membrane.
What are the official names of this protein?
Cornifin-A, 19 kDa pancornulin, SPRK, Small proline-rich protein IA, SPR-IA.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB6_JASNU
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLGVLTASFGVTGYSLPRDQIGYWAVKIVTGVPEAIPVIGAPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFPMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NU1C_OENEH
Sequence: MIIDTTAVQDMNSFSRLQSLKEVSGIIWMLVPILSLVLGITLGVLVIVWLEREISAGIQQRIGPEYAGPMGILQALADGIKLIFKENLLPSRGDTRLFSIGPSIAVISILLSYSVIPFSSHLVLSDLNIGVFLWIAVSSIAPIGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLTLCLLSISLLSNSSSTVDIVEAQSKYGLWGWNLWRQPIGFLVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYVASYLNLLVSSLFVTVLYLGGWNISISYIFVPGLFEITKVGRVFGTTIGIFTTLAKTYLFLFISITTRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSSQLLSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: BCLA3_MOUSE
Sequence: MARSRSRSPRWKQRSLSPQSRNFEYHEERHFHGHYDPEYRHDQQRPFTWRMDDEKHGQNKPRIPPRVNSYHRSYVNRSPSPNVKPVEKFDTYKPHQEYFPGRGDDDRRSQYMPTYTESAATYMEHERDCYIPTVQGRYTPDDHRGRGRGSGRGEKPPQMSLGKPPKMSLGKPPQMSLADSLRFKEKWHEDELRHQRVQEESYPQSPRRGSEDFGTRNPFQKRYPEDHDFRKYGYTSKRPTDAARYENRDPARIPKWKPEHSFLPFQEKKEEWSFGAQGHRYTEREYPERSSTTRVSYDYRHKHHKLSESEQDFPDGRFHKHLKEEDRKYSSIKAPANRELDCFSTTRGREIENEQINGPFYLYNKNSVSYNHTNIKDADLEPCNDKWKKKISKEDCRKENASFSKQFDTSPKPEEKCYSLIKKKPLSVKVDRNKTDTFRSTSRYSAERQISHDLVAIGKTSDNFHPVFQHLDSTQNPENKPTEEFAQEIITLIHKVKADSFVTPDITLNERFSRIKNRQDADFNQTKSNSDPEFHRRIDMSLDDFQNKYTMVYEPDKTLVKVIEPNDLRHDIERRRKERLQNEDENIFHMASPTERNHQSPSFSKVKTIRADGFQKPPHFIKSNFRKFIQKPYINYTMQRKDAIDQKIFRVEENHQNRRGSKGSFKNFLGGRFQPHYKSHLVQKSMYIQAKYQRLRFAGPRGFITNKFRNRFLRKKKEYPVLPRTNNLELLQVEPTLYEDLTEHLIFVRNWN
What are the official names of this protein?
BCLAF1 and THRAP3 family member 3.
What is the protein family that this protein belongs to?
Belongs to the BCLAF1/THRAP3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SBE2_YEAS7
Sequence: MTARRLINIVPNTSKLDPLKEEDSTHLKQNQPKKFSTKELMLSEYTERKSCSLPLSKSRSGSSASSSTTGSNGKNIGTRRPSSNLDFNFASQDVVKNVLGNNNPHVPTAKCIRPISDDSIGTSSTEIFSSSHSNTTSDSLCTSDISSEEGEIANSKMEDNCFFKSMREADHRSNITPLKKSRPGSILQKTRTASSADKTICSMSTITTCIPSRQNSVSTPKLSRTVGLPGSSNTTNSIAASQTSFISENDSPLKHHCMSTATIQEPKLMPITKTPYVHSNSTSVILPYKTTQLTPSQRYRLRKEQNDQSLRKAIKMKEKFYEDQDVNLELQEGDVDGSLIWNIPMASLSTSSFLTLSKFNRKEMSLDSARGDEEILIQENNCEGKQHSSSALCVDKTFHQVHSTRKHTSNSSNTLKESCLDYKELPPTCIPGISPVSDSQYIQDTMKNLSQIYLHSSEKISKSILSGRSRSVQSLPLEFKEASSQGMEDLMLVSEDKLKAVSHFRPSWLPPKDFKERKLQDKQIYKNIDLASMEELQKNKERDEKAKKNEQNKVKFQHLLDRGITRNSSLSELKKIIWETPLISKVRLQIYSQLLQSDNCLITKCFIESFEEVMQLLNKMDFPKDKEFEIRQLIEHDVQEKVFYKNGTDKQVVSDLMLLLQLKSISQQGLVTGDEMLFYHFLTDQSFGTLKETWEMVNLIQMTCFSEICKEKYDSRILNPRGIVAHLLRKDEFKNEFNGGCLNSNTWWNILQRMDHKLFMWVMDVIIVHNGQNFANYPVKMEIFKDKVWEYYRSKKVIVNYKILVSLTVNVLLNYHFGYDNLKHLSDLDDKHFCIPLYTEDSIEEENLNNIFTKWWLHYYRKLR
What is the function of this protein?
With SBE22, is involved in cell wall integrity and polarity processes like bud growth, through the transport of CHS3 and UTR2 to sites of growth.
What are the official names of this protein?
Protein SBE2, Suppressor of BEM4 protein 2.
What is the protein family that this protein belongs to?
Belongs to the SBE2 family.
Protein: BIOB_METS4
Sequence: MTTTERSDPAIRHDWTVAQVQAIHDMPLLDLVHRASLVHRAHHDPSDIQRASLLSIKTGGCPEDCGYCSQSAHHKETGVARQRLMPVEAVLREAAAAKAAGATRFCMGAAWRSPKDGPDFDAVLAMVRGVRGLGMEACVTLGMLTPSQAERLAEAGLTAYNHNLDTGPDYYDKIVSTRSYEDRLATLQAVRDAGIGVCCGGIIGMGEGVTDRVAMLQVLANHAPHPESVPINALAAVPGTPLGERPPVDPFEMVRMCATARIVMPRARVRLSAGRRALSREAQVLCFLAGANSIFYGERLLTTANTDADADAQLLRDIGVPVPAISALEAAE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: MODD_ECO27
Sequence: MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGGCVSGISVACKMLTTLGLTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAVQNVLEWSCGVSDYLAQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETILLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADAPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLALTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
What are the official names of this protein?
Putative pyrophosphorylase ModD.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: YADS_AERCA
Sequence: MQTLVEQIVYISDMFGTAVFAFSGVLVAGRLRMDGFGVMVLAAVTAIGGGTIRDMILGATPVFWVRDPLYIWVVIATALIGMWMVKLPRRMPWYVLPVADAFGLALFTVIGAQKALNFGTSGLIAVLMGTMTGVAGGMIRDVLAREVPMVLQKEIYATACILGGILYTLSLEVGVDRVSAMLISMLGVFGLRVAAIYWHLSLPTFSLQRN
What are the official names of this protein?
UPF0126 membrane protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0126 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GBDR_PSEAE
Sequence: MTTYAPGVPPQNRNPQSIGFLLLDNFTLISLASAVEPLRMANQLSGRELYRWHTLSLDGRQVWASDGLQITPDAGTDNAPAVDCVIVCGGVGIQRSVTREHVTFLQAQARQGRRLGAVCTGSWALARAGLLDGYDCSVHWECLAAMQEAFPRVAMSTRLFSIDRNRFTSSGGTAPMDMMLHLIGREHGRELSAAISEMFIYERIRNEQDHQRVPLKHMLGTNQPKLQEIVALMEANLEEPIDLDELAVYVNVSRRQLERLFQKYLHCSPSRYYLKLRLIRARQLLKQTSMSIIEVASVCGFVSTPHFSKCYREYFGIPPRDERQGQPLGQPVVLMPIPQDLALMPNSSALSALSQAQGESTFASVRI
What is the function of this protein?
Specific regulator of choline metabolism, which activates transcription of at least 25 genes from 11 promoters in response to choline metabolites (PubMed:24097953).  Required for the induction of plcH, encoding the phospholipase C, and pchP, encoding the phosphorylcholine phosphatase, in response to glycine betaine (GB) and dimethylglycine (DMG) (PubMed:19103776).  Also controls the expression of gbcAB and dgcAB, which are required for GB and DMG degradation, respectively, in response to both GB and DMG (PubMed:17951379).  The GbdR regulon also includes genes encoding sarcosine, glycine and serine catabolic enzymes, the BetX and CbcXWV quaternary amine transport proteins and the acetylcholine esterase gene, choE (PubMed:24097953).  Acts by binding directly to the promoter region of the genes (PubMed:19103776, PubMed:24097953).  May play an important role during P. aeruginosa interactions with eukaryotes (PubMed:17951379).  Is critical for induction of plcH and pchP in response to bovine surfactant and mouse bronchoalveolar lavage fluid (BALF) (PubMed:19103776).
What are the official names of this protein?
HTH-type transcriptional regulator GbdR, Glycine betaine/dimethylglycine responsive regulator.
Protein: ILVC_YERPA
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADEAGYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSAVVKAVQPLMKEGAALGYSHGFNIVEVGEQVRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLEFSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVSEGTDAAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGAFSSGMMADWANDDVKLLNWREETGRTAFENAPQFEGKISEQEYFDHGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKEKFMDSLQAGDLGKSIPGSAVDNAQLRDVNEAIRNHPIEAVGHKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: IPYR_CANGA
Sequence: MVYTTRQIGAKNTLDYKVFIEEDGKPVSPFHDIPLYADKEENIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRYVRNCFPHHGYIHNYGAFPQTWEDPNQTHPETKAVGDNDPVDVLEIGETIGYTGQVKQVKVLGIMALLDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYALDIIKETNESWKQLIAGKSTDSKDIALENTKVTDSPYYSASAASAIPAAAPQADAPIDKSVDKWFFISGSA
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.