PharMolix/UniProtQA huggingface dataset:
Protein: RBN_ECOLI
Sequence: MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQHQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVETALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPLEHPLECYGYRIEEHDKPGALNAQALKAAGVPPGPLFQELKAGKTITLEDGRQINGADYLAAPVPGKALAIFGDTGPCDAALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYDDKGCQHLLRECRSIFPATELANDFTVFNV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities, depending on the nature of the substrate and of the added divalent cation, and on its 3'-terminal structure.  Can process the 3' termini of both CCA-less and CCA-containing tRNA precursors.  CCA-less tRNAs are cleaved endonucleolytically after the discriminator base, whereas residues following the CCA sequence can be removed exonucleolytically or endonucleolytically in CCA-containing molecules.  Does not remove the CCA sequence.  May also be involved in the degradation of mRNAs.  In vitro, hydrolyzes bis(p-nitrophenyl)phosphate and thymidine-5'-p-nitrophenyl phosphate.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: NNR_MOOTA
Sequence: MYLVTAAEMGQLDRLASSEYMIPSIVLMENAGLRVVESIERHFQGQVANRRILIFCGKGNNGGDGLVVARHLLNRGAEVKVFLLARPEDIRGDARTNLEIYQKMGGKLLLLLGESHLQRADIALLYADLVVDAIFGTGFKGAAMGLPAAVINMINKAHRETVAVDLPSGLEADTGRCFGPCIQATWTVTFALPKLGLVVEPGASLTGRLEVADIGIPQKLVATQHFNRRLLTAAWCRSQLPRREASGHKGLYGRVLAVGGSPGLTGAITLAATAALKAGAGLVTAAVPRGVQGILAMKTTEIMTMSLPETPAGALSRDALDPLLERLAEVDVLAIGPGLSRDPATVDLVKELLPRVQVPAVVDADALNALATDTRVLTGDHGPLVLTPHPGEMARLLGTTAAKIQEDRLEIAAKYAREWQAVLLLKGARTVIAWPDGQVYINPTGNPGMATAGSGDVLTGIIAGLAGQGLKPGVAAALGAYLHGAAGDEAARQRGQRAMMAGDLLDFLPYVLRNLEEEVETIVAAGLGRD
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: GDF15_HUMAN
Sequence: MPGQELRTVNGSQMLLVLLVLSWLPHGGALSLAEASRASFPGPSELHSEDSRFRELRKRYEDLLTRLRANQSWEDSNTDLVPAPAVRILTPEVRLGSGGHLHLRISRAALPEGLPEASRLHRALFRLSPTASRSWDVTRPLRRQLSLARPQAPALHLRLSPPPSQSDQLLAESSSARPQLELHLRPQAARGRRRARARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRAANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQTYDDLLAKDCHCI
What is the function of this protein?
Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435).  Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099).  It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which constitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886).  On hepatocytes, inhibits growth hormone signaling (By similarity).
What are the official names of this protein?
Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS1_ACIET
Sequence: MTQQITLALSKGRIFEETLPLLAAAGIEVLEDPEKSRKLILPTSRPEVRVVLVRATDVPTYVQYGGADLGVAGKDSLIEHGGQGLFRPLDLKIAKCRVSVAVRADFDYREAVTQGSRLKVATKYTSIARDFFASKGVHVDLIKLYGSMELAPLTGLADAIVDLVSTGNTLKANNLVEVEQIMDISSHLVVNQAALKLKQAPLRRIIDAFASAVPQG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_PSEPU
Sequence: MSLTNEQIIEAIGQKTVLEVVELIKAMEETFGVTAAVAAAGPAAAAAVVEEQTEFNVVLVEAGDKKVNVIKAVRELTGLGLKEAKEKVDGAPQVVAEGVSKEAAEDAKKKLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CARME_DICDI
Sequence: MTKNKSKNKSNNSNISNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNGESQLKNKNKNISENQHIYDKHNHDHSHDHNHDYDDNNEDDEEKEELEHYQLIVSTLLNYSQYSLHWVKDMQDFFHYKLSEDEKKLLPNYNAKMEALARAVLVNSQFLKKIGNEHCNIFSQSSDNSANSERIVDPTNLDHIKIDYFMMDQLKSTIRQLVREWSEEGKLERDQAFEPIKQQLLEIYGHIPFQERSKIRVYSPGAGLGRLCLEIASLGFSSQGIEYSFMMLIVSNFMLNKVEKINEFKIHPYIHQTVNVLRDIDQLRTVTIPDVLSSELLPKNNPALEFSMSAGDFTKNIEENSFDCICTCFFIDTAPNILEYVDCISKILKPGGTWINFGPLLYHHAKKKDSIELSYEQLRYLICKKQFQFKKEEIRDAEYCSNQKSLLRSIYKCQFFVVINNKPT
What is the function of this protein?
N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine.
What are the official names of this protein?
Carnosine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the carnosine N-methyltransferase family.
Protein: Y1977_PSEAE
Sequence: MPDRRTLLLTVLAMLAFAGNSLLCRAALKDTAIDAVSFTALRLFSGALMLAVLLHLRRRPATPARGGWRGAAALFVYAAAFSYAYVQLDAGTGALLLFGAVQVTLLLAGLLRGERLGGQALLGFLLALGGLLFLLLPGASAPPLGGALLMLLSGLAWGLYTLLGRGGGDPLAVSAGNFLRALAFAALLLLAFHGQLRLDGAGLAYALLSGALASGLGYAVWYSALPGLTAIQGASVQLSVPVLAALCGALLLGEPLAPRLPPATLAVLGGIALILAPRLGRAAREGA
What are the official names of this protein?
Uncharacterized protein PA1977.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGR_STAA1
Sequence: MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCC3_STAA3
Sequence: MSKIVVALGGNALGQSPKEQLDLLKSTSKSLVSLIDKGYEIVISHGNGPQVGSINLGLNYAAEHKQGPPFPFPECGAMSQAYIGYQMQESLQNELHSMGIDKQVVTLVTQVQVASDDSAFNNPTKPIGLFYTKEQADKFTKEKGYTFVEDSGRGYRRVVPSPQPISIVELDSIETLITHGTLVIAAGGGGIPVIKENEVYTGVDAVIDKDKTSALLAAHLQSDQLIILTAVDHVYINYGKENQRGLDEVSVDEMKKHISDGQFAKGSMLPKVEAALQFLEKNTKGSVLITSLAGLGDALDGKIGTLIKN
What are the official names of this protein?
Carbamate kinase 3.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_SHEDO
Sequence: MLERIKDSFTESIQTKIDAAEALPESIEKAAEMMVQCLLGGKKILACGNGGSAGDAQHFSAELLNRYEIERPPLPAIALSTDTSTITAIANDYSYDEIFSKQIFALGQPGDILLAISTSGNSGNIIKAMEAALSRDMTIVALTGKDGGAMAGLMSAGDVEIRVPSNVTARIQEVHLLVIHCLCDNIDRTLFPQDEA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGD1_SCHPO
Sequence: MKSNLSLKRQDEKRADKEPNLYTLQGVIQYLQYEAFKNERDHNLWEIERAELKIRVAQLERERAKLEQSLSFQQRRAEMLEKSLRELRKDKNISVKDLDEFHLLDKPAANNTKADAEACLLKSKNYIKKSLQEIVYLTNMQPNVSWNVLQEPTRGIKVPKESNNTQQNNQFVMEPSQNKGNVNDANFFEVEYARNENMNKLSSSELISDDLLEDEIMKPLSSGESLPKKEEEVTKSPSFTLDDSVASNEQTLAQLNIESPVDQKKSKAKKKKEQKWTLKFESDKGTSTQCITHQPLPGSTPSFASGTENGVINVWRLDEDSNDNSMGIIKPHLTFYGHEGPVLCVCVPKATHHIFSGGHDGTIRCWSLPANQTSDSISKILTGSTIFQGHEDCVWELFCHEVKDNNPILLSLSSDGTVRGWKYTGEQLFKIRCDSKQPLSMSVTDSRIAIAYNDGNVRFYDLDTQILVSQMRIAGNSAIGNPAVKDRINKIVWKNGNPDRLYSLHENGMVRVFDVKSEELLAEKSISKVSLTGIAFAVNRPEFAISASDGRVFFLRQDDKLSTLESLPSREAQEEITDLSDILWINSPVDKLEHLIVGCKERISVYDRKYLP
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C1773.01.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDRD5_RAT
Sequence: MSEQERIQDCLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIASLVAKQRRSHKVRNSMQKGRSSVCSGRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFEKAFARRFGRSFQYMQYGFLSMFEVLSAASDVICVEQTRAGSLLTLKKSASEEKQREWPAGKIFTQPFRMKQQGSYSTGFPVTKTRFSQPISNMEPPKQVLSMEKIPMFNTVEASRLSHTEKLNQLESTFKSVIAQIGPGGTVDPDLKHKIKFVVSKFPQGLFISKLLGEFELVFKEQLSPKQLGFLNVTELVGALSDILRVEFSEEKQDLLVFDADLRPLLPAGPLSSVRNSCLVQPDKRIEANAWASSPSRNSLSTVAVKKTTWDCPLKNHKEAEQKAYKKPNLVVKPLQLQVETNKSQLSLSMANHDIPPDAVRAKKLCRLPPLDTSTLVGVFVEYIISPSQFYVRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPEYFIQPGHLCCVRISEDKWWYRVIIHRILGKKEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPAEEHWTSKAILHFQKLCGLKPLVGVVDEYIDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENAPSKGFRDFNPPALYTNSSAAPGDMVLTELGHPAQQHYLNEDGEILQQPQQDINDEKSISHLKSVSEELLKDSKLGPLKTRESCEEEPQWSILKPKDPKEENEDEVPTGMPCLESVTIGDDIWDENWLPLQAKMGKAGGPASHLFTSSLVGKKQYQTRGETTRKDWCFSTSKDIWDDSWQPLGLANDVKGRTHTPEGPIAQEKNIGTTRIRKQPDLQYPLDSSTLPKLEEFYISLIKSQQSAEGSQSEPASIQTPLKPGQASSTAPSSTPAAGDSPENHSGSAPDFSEALHSSKYSHGCLGSSCAVSHVQEPPALVPQCERREA
What is the function of this protein?
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity.  Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Required for chromatoid body (CB) assembly (By similarity).
What are the official names of this protein?
Tudor domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the TDRD5 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.
Protein: USTC_ASPFN
Sequence: MSPFIFAVTLTFAILALGILRRRYFHPLSRFPGPFLGSVTSLYQTYWHVHPNKTLHDTELHRKYGPIVRYSPNGLIVNDPALLPVIYNRRANKTDFYAPVFDTHSTFTRKDYREHVASRKAISHAVGFLAFFRTEYSYGLVLLMIIFKQYSVTNTRLFEPQVDGILSELAGSSVTPSQLARVIFHISRNFKVQEKLYEELVAAEQDGRIPPLSAIISDEQAHRLPFLSACIREAQRYAPTMSQLPRYAPEGTGLELHEQYVPPGTSVSTSPWIIGRNKDLYGEDANSFRPERWLEASPEEERRWDHFSFHFGYGARKCLANNFGLMQLYKVAAEVCAYPIRCLLRYRAHHECRYFVVLKLKLKGRTRIQSVEGRLRVPGFALIAEQDPGHKHNGYINMDLFRA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the secondary metabolite ustiloxin B, an antimitotic tetrapeptide (PubMed:24841822, PubMed:27166860, PubMed:26703898).  First, ustA is processed by the subtilisin-like endoprotease Kex2 that is outside the ustiloxin B gene cluster, at the C-terminal side of Arg-Lys, after transfer to Golgi apparatus through the endoplasmic reticulum (ER) (PubMed:24841822).  Cleavage by KEX2 generates 16 peptides YAIG-I to YAIG-XVI (PubMed:24841822).  To process the precursor peptide further, at least two peptidases are necessary to cleave the N-terminal and C-terminal sides of the Tyr-Ala-Ile-Gly core peptide which serves as backbone for the synthesis of ustiloxin B, through cyclization and modification of the tyrosine with a non-protein coding amino acid, norvaline (PubMed:24841822).  One of the two peptidases must be the serine peptidase ustP; and the other pepdidase is probably ustH (PubMed:24841822).  Macrocyclization of the core peptide derived from ustA requires the tyrosinase ustQ, as well as the homologous oxidases ustYa and ustYb, and leads to the production of the first cyclization product N-desmethylustiloxin F (PubMed:27166860, PubMed:26703898).  For the formation of N-desmethylustiloxin F, three oxidation steps are required, hydroxylation at the benzylic position, hydroxylation at either the aromatic ring of Tyr or beta-position of Ile, and oxidative cyclization (PubMed:27166860).  UstQ may catalyze the oxidation of a phenol moiety, whereas the ustYa and ustYb are most likely responsible for the remaining two-step oxidations (PubMed:27166860).  N-desmethylustiloxin F is then methylated by ustM to yield ustiloxin F which in turn substrate of the cytochrome P450 monooxygenase ustC which catalyzes the formation of S-deoxyustiloxin H (PubMed:27166860).  The flavoprotein monooxygenases ustF1 and ustF2 then participate in the modification of the side chain of S-deoxyustiloxin H, leading to the synthesis of an oxime intermediate, via ustiloxin H (PubMed:27166860).  Finally, carboxylative dehydration performed by the cysteine desulfurase-like protein ustD yields ustiloxin B (PubMed:27166860).
What are the official names of this protein?
Cytochrome P450 monooxygenase ustC, Ustiloxin B biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: ZITB_ECOLI
Sequence: MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGSLALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVITILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHVLGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPVSLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYLMDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH
What is the function of this protein?
Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc.  It may contribute to zinc homeostasis at low concentrations of zinc, whereas ZntA is required for growth at more toxic concentrations.
What are the official names of this protein?
Zinc transporter ZitB.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNPA_STAAS
Sequence: MEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CNSK_PENEN
Sequence: MERSLSFEPYLLTPLDHIIKDFYVSSFISFPLHDPTTAVSALKDGVERLTRALPFLSGARVPSSKLPGKRNVMEIHPSPESLEWIPMLQIKHYRDTTLVATCSPGPTGCSDLDDSWCALPIIIPADRPSPVARFRASVFPDGILLCMTLNHAVFDGSGLGTVLKMLATCCCANSAMDHPVSLPTTYAKEASSRQIILESAAPSSGSDSEAYDRIFKSNDIIPGLDKGITSRRFSFPASKIRALKDACNAAKPTDQDPAISRNDVLTALLTICMTRARQTEQTKNLTTQLAVPVNLRRKFHPSLPDSYLGNTIIPLVVDIDPPTVPSSRCGTSPMHAHLNELTNLSLRIRKELKLLDEKDYTGGLVSYLREQSDWGATSMKFTDITVSSLRHLDINGLDFGPEIGRANSFDVQSGMYPGICDIMPTCGRDRVEDINDVPWDVCVTLEDSAWSAFMEDDLVLWALEKI
What is the function of this protein?
Communesin N16 acyltransferase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals (PubMed:25571861).  Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptophan (PubMed:25571861).  The L-tryptophan decarboxylase cnsB converts L-tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L-tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the aurantioclavine synthase cnsA, probably aided by the catalase cnsD (PubMed:25571861).  The cytochrome P450 monooxygenase cnsC catalyzes the heterodimeric coupling between the two different indole moieties, tryptamine and aurantioclavine, to construct vicinal quaternary stereocenters and yield the heptacyclic communesin scaffold (PubMed:26963294).  The O-methyltransferase cnsE then methylates the communesin scaffold to produce communesin K, the simplest characterized communesin that contains the heptacyclic core (PubMed:25571861).  The dioxygenase cnsJ converts communesin K into communesin I (PubMed:25571861).  Acylation to introduce the hexadienyl group at position N16 of communesin I by the acyltransferase cnsK leads to the production of communesin B.  The hexadienyl group is produced by the highly reducing polyketide synthase cnsI, before being hydrolytically removed from cnsI by the serine hydrolase cnsH, converted into hexadienyl-CoA by the CoA ligase cnsG, and then transferred to communesin I by cnsK (PubMed:25571861).  Surprisingly, cnsK may also be a promiscuous acyltransferase that can tolerate a range of acyl groups, including acetyl-, propionyl-, and butyryl-CoA, which lead to communesins A, G and H respectively (PubMed:25571861).  The roles of the alpha-ketoglutarate-dependent dioxygenases cnsM and cnsP have still to be determined (PubMed:25571861).
What are the official names of this protein?
Communesin N16 acyltransferase cnsK, Communesin biosynthesis cluster protein K.
What is the protein family that this protein belongs to?
Belongs to the fumigaclavine B O-acetyltransferase family.
Protein: Y1362_MYCTO
Sequence: MTDDVRDVNTETTDATEVAEIDSAAGEAGDSATEAFDTDSATESTAQKGQRHRDLWRMQVTLKPVPVILILLMLISGGATGWLYLEQYRPDQQTDSGAARAAVAAASDGTIALLSYSPDTLDQDFATARSHLAGDFLSYYDQFTQQIVAPAAKQKSLKTTAKVVRAAVSELHPDSAVVLVFVDQSTTSKDSPNPSMAASSVMVTLAKVDGNWLITKFTPV
What are the official names of this protein?
Uncharacterized protein MT1407.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1363c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PYRG_ACIB5
Sequence: MTHFIFVTGGVVSSLGKGISAASVAALLEARGLKVTMVKMDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGYYERFLRRAKMTKLNNFTSGRVYQDVLNKERRGDYLGGTVQVIPHITDNIKERVLRAGEGYDVAIVEIGGTVGDIESLPFMESVRQLMVELGHKRTMLMHLTLLPYIKSAAELKTKPTQHSVKELLSIGIQPDILICRTEYDVDADTKRKIALFTNVEARAVVVCKDAKTIYQIPRGFYEQNVDDLICERFGFTDLPEADLTDWDNVVEALLNPEYTVRVAMVGKYVELPDAYKSVNEALLHAGIKNRVKVQIDYVNAEELESQDVSILKTADAILVPGGFGERGTEGKMKAIQYARENGIPFLGICLGMQLAVIEYARHVAGMPEASSTEFNRSTKYPLIGLITEWLDERGELQQRSLESDLGGTMRLGAQKSELVEGTKTREVYGKAEITERHRHRYEMNNRFIEAIEQAGMKISGYSSAQHLVETVEIPEHPWFIAVQFHPEFTSSPRDGHPLFASFIDAAKTQHQKSK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: QUEC_GRABC
Sequence: MIETKPIPGLALPRHDHALVLFSGGQDSTTCLAWALERFAHVETIGFTYGQRHSVEMECRGRVRQVLAHMSGRSGADWGSRLGDDHVLDLGNALHHVGQSALTGRSPIEIGQGGLPTSFVPGRNLIFLTYAAALGWRRGLRRMVGGMCETDYSGYPDCRDDTIKAMQLALNTGMEAHFVLETPLMWLTKAETWALADSLGGPALVALIEEETHTCYLGDRSQRHPWGYGCGECPACSLRAEGWREWQTASSA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ASSY_SHEAM
Sequence: MAIENSKTGVKKVVLAYSGGLDTSAIIPWLKENYDNCEIVAFCADVGQGEEELVGLTEKALASGASECHIVDLKEEFVKDYIYPTIATGAIYEGTYLLGTSMARPIIAKAQVEVARKVGADALCHGCTGKGNDQVRFEGCFAALAPDLKVIAPWREWDMESREDLLAYLAERNIKTSASATKIYSRDANAWHISHEGGELEDPWNEPSKQVWTMTVDPLDAPDEPEYVTLKIENARVTEVNGEALSPYQALMKLNAIAAPHGVGRIDITENRLVGMKSRGCYETPGGTVMFAALRAVEELVLDKSSREWREQVAARMAHLVYDGRWFTPLCDSLLAASESLATMVNGEVVVKLYKGQAVPVKKRSPNSLYSEAFATFGQDSVYDQKHAEGFIRLYSLASRIRAYNTK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_BACC3
Sequence: MAELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQIARHAERPTTLDYIEHLFTDFFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKGAYPGKAAEERGQSEAIARNLFEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAKEAAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDELIEKRYEKYMKIGQVSFSNASIWIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMC_ECO27
Sequence: MQCALYDAGRCRSCQWITQPIPEQLSAKTADLKNLLADFPVEEWCAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALKPFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSDTKLAQLRKALPWLQEQLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVASQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIAPEAIACAKQSAAELGLTRLQFQALDSTQFASAQGEVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSCNAQTMAKDIRELPGYRIERVQLFDMFPHTAHYEVLTLLVKQ
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: FUCM_ECO81
Sequence: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.