PharMolix/UniProtQA huggingface dataset:
Protein: DGAT2_XENTR
Sequence: MKTIIAAYSGVLRGTGSSLLSAVHDLPNIPWLSKSSVVRHLQIISVLQWVLSFLILGVACTAVLVYIFCTDLWLIAALYLTWMVLDWNTPYKGGRRSSWVRNWAVWRYFRDYFPIKLVKTHNLLPSRNYIFGYHPHGIMCLGAFCNFGTEATGVSKKFPGIKCHLATLAGNFRMPVLREYLMSGGICPVARDTIDYILSKNGTGNAVVIAVGGAAESLNCRPGKNTVTLKQRKGFVKVALQHGADLVPVYSFGENEAYKQVVFEEGSWGRWIQKKFQKYVGFAPCLFHGCSFFSSNSWGLVPYANPITTVVGEPITVPKIEQPTQKDVELYHAMYVTSLQRLFDKYKTKLGLHDSEMLEIV
What is the function of this protein?
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.  Required for synthesis and storage of intracellular triglycerides.  Probably plays a central role in cytosolic lipid accumulation (By similarity).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 2, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet. Cytoplasm, perinuclear region.
Protein: PYRE_METJA
Sequence: MDKKSKLINLLKEVGCIRFGEFILASGKKSNYYIDIKKATTNPEILKLVGEIIAEQIKDEDVKVAGVELGSVPIATAVSIIAQKPLLIVRKKPKDYGTKNKIEGELKEGDKVVIVEDVTTTGGSVLKAVKEIRENGGIVDKVFVVVDRLEGAKENLQKENVELIPLVTVKELQSTQ
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TILS_METCA
Sequence: MRLSLDSFRAGLHPGSTYRVAFSGGLDSAVLLDLMCQVRRVSGIGVRAIHVHHGIQPEADAWSRHCAAVADRYGVALDILQIDGRSRPGDSPEAAARTARYHSLEASLDPGDILVTAQHLDDQAETLLLQLLRGAGLAGLAAMPNAVPFGAGILHRPLLRFGRRDILAYAQERGLSWIEDPSNRDERYDRNFIRRRILPQLAGRWPAVAANLTRSAGHCAEAAGLLDRLADTLMAAATAADEPGTLVLEIVQRLQPDEQRLLLRRWIHKRGLRAPPAKLLERIRKEVVETAGDRTPMIAWAEGTVRRYRHRLHLLPPSADFDASWTAAWSGETPLTLAGNGCLHAALCPGPGIDPDKWRSGRITVRYRRAGDRLEPAGRRGHHELKKLFQEAGLPPWLRDRQPIVCIDGRIASVGGSQWLASEFAGAPERVNIVVHWTP
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNG2B_XENLA
Sequence: MDNDSQYSGYSYKSGQSRSSRKHRDRRERHRSKSREGSRGDKSVTIQAPGEPLLDNESTRGEDRDDNWGETTTVVTGTSEHSISHDDITRITKDMEDSAKLDCSRHLGVVIAGALALLSFLTPIAFMLLPQILWREDLEQCGTACEGLFISVAFKLLILLLGSWALFFRRPKAFFPRVFVFRALLMVLVFLLVVSYWLFYGVRILESRDKNYQGIVQYAVSLVDALLFVHYLAVVLLELRQLQPQFTIKVVRSTDGASRFYNIGHLSIQRVAVWILENYYHDFPVYNPALLNLPKSILSKKMSGFKVYSLGEENNTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRKARLVVAVEEAFTHIKRLQDEDPKNPREIMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLGPGPTIQYHKDRWLAKQWTLVSEEPVTNGLKDGVVFELKRQDFSLVVSTKKIPFFKLSEEFVDPKSHKFVMRLQSETSV
What is the function of this protein?
Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruit dvl/dsh and prickle from the cytoplasm to the plasma membrane.  Acts in a PCP complex to regulate the polarized assembly of fibronectrin on the surface of the mesoderm during gastrulation.  Regulates convergent extension in both dorsal mesoderm and neural tissue without affecting cell fate.  Regulates neural fold closure during neurulation (PubMed:12074560, PubMed:15854914).  May be required for cell surface localization of fzd3 and fzd6 in the inner ear (By similarity).
What are the official names of this protein?
Vang-like protein 2-B, Protein strabismus-B, Van Gogh-like protein 2-B, Xstrabismus-B, Xstbm-B.
What is the protein family that this protein belongs to?
Belongs to the Vang family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Cell membrane localization is regulated by prickle.
Protein: RL1_STRZT
Sequence: MAKKSKQLCAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEVAYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVAKINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQGVGIKVDVNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: M1_I67A2
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEVALSYSAGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: IF2_BORPD
Sequence: MSSNTVAQFATELKMPANVLLEQLRSAGVDLNSVDDAVTDSDKAKLLDSLRRAHGATEGKKITLTRRQTSEIRQADATGRSRTIQVEVRKKRVFVKRDPSEIALEQARADAAASDAAPAEPAPAAAEPSASAPVTAPVNAPAADAPQAPATAAPDTAAPAAETPSQPPAVEPQPAPVAQAEPEPQPEPVAKPAEAPAEPAAPAAVEAHAEREAEQAPPEPAVQAEIETAPAPAAESAQAARPEPVTPKAEPAPAASKPARAEGRRGAPVPVAAPAVDSAGREEARRAAEAEAAALREMLNRPRKVLRAPEPEAGALSGTLHKPAGKAAAPGAKKDAKPGAGGSKKTIKTAEVASTWSDDASRKKPADTKSAAPSRDGWRAGGKGGKGGRNSRNQQAERRHEPAPQEFIAREVHVPETISVADLAHKMSVKAAEVIKQLMKLGQMVTINQVLDQETAMIVVEELGHVAIAAKLDDPEAFLDETPVASEAEALPRAPVVTVMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETARGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTREAIHHAKAGGVPLVVAVNKIDKPEANPERVKQELVAEEVVPEEYGGDVPFVPVSAKTGAGIDDLLENVLLQAEILELTAPVEAPAKGLVIEARLDKGRGPVATILVQSGTLKRGDVVLAGASFGRVRAMVDENGKQIQEAGPSIPVEIQGLTEVPAAGDELIALADERKAREIALFRQGKFRDVKLARQQAAKLESMFDNLGEGTQTLPLIVKTDVQGSQEALVASLTKLSTDEVRVQVVHAAVGGISESDINLAIASNAVVIGFNVRAEQSAKKLAESNGIDVRYYNIIYDAVDEVKAAMSGMLAPEKKEEVIGLVEVREVYSISRIGNVAGCMVLDGLVRRDSQIRLLRNNVVHWTGHLDSLRRFKDDVKEVKSGFDCGLTLRGSNDIQVGDQLEVFEIKEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1M_ASCSU
Sequence: MILMLVQVILIMIFVIQSIAFVTLYERHLLGGSQQRIGPNKVSFMGFLQAIFDGVKLLKKEQMTPLNSSEISFILVPGIFFIVMYLEWFVLPFFYDFMTFEYSILFFLCLIGFSVYTTLVSGMVSKSKYGMVGAIRASSQSVSYEIAFSLYLLAIVMHINMFCFFSFFNLSLFIVYLPFLFMVLAELNRAPFDFAEGESELVSGYNVEYSSVAFVLLFLGEYGALLFFSTLTSVLFFGFSYVVIYCMFTILVFVRSSYPRFRYDLMMYFFWFKLLPVSLIFLGYFVIFLF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NTP2_TOXGO
Sequence: MWLPVYVPLLLVFGVSLSLPHGSLGTDSSSLRGVDADTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARCMIDEYGVKHCRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGREMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNL
What is the function of this protein?
May perform an important processing step in the conversion of high energy nucleotides prior to uptake by the parasite.  NTPAse-II has a specific activity 4. 5-fold lower than NTPAse-I in hydrolysis of ATP.  The primary difference between these isozymes lies in their ability to hydrolyze nucleoside triphosphate versus diphosphate substrates.  While NTPAse-II hydrolyzes ATP to ADP and ADP to AMP at almost the same rate, NTPAse-I hydrolyzes ADP to AMP at a much slower rate (0. 7% of the rate for ATP).
What are the official names of this protein?
Nucleoside-triphosphatase 2, NTPase-II, Nucleoside triphosphate hydrolase 2, Nucleoside-triphosphatase II.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Secreted. Parasitophorous vacuole. Note=Found in host cell parasitophorous vacuole.
Protein: P2R3A_HUMAN
Sequence: MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPVSQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFASGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSSSVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCSEDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSGNNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNSRKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEESDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNLPKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFLNSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIEDFAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQTPEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha, PP2A subunit B isoform PR72/PR130, PP2A subunit B isoform R3 isoform, PP2A subunit B isoforms B''-PR72/PR130, PP2A subunit B isoforms B72/B130, Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B.
Protein: TRMB_RHOP2
Sequence: MVTIDRRVQPIAHLACNHQRAFIDMNESVHHQGSFFGRRKGHKLRAHQADLVDKLLPHLALAIDGPAPASLVELFDPPVEAVRLEIGFGGGEHLIAEALAHPSTGFIGAEPYVNGMAKILARIEQENIRNIRLFAGDAAALMAWVPAHDLNRIDLIHPDPWPKRRHWKRRFVQDAMVGAMARALRANGEFRFVSDIDSYNAWTLAHLLRAPDFDWTAERADDWRKPWPNYTMTRYGRKAEREGRRAAYLRFRRRAA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: KDUI_LACP3
Sequence: MAFHMATRYAHSPEDIKHFDTTKLRQEFLMEKIFNAGDILLTYTYNDRMIFGGVVPTESSLEIKLSKELGVDFFLQRRELGVINIGGPGSIIVDGDKAAMVKQDGYYIGMGTKQVVFASDNPANPAKFYVVSTPAHKTYPNKKLPFANALAKPMGDQQHLNKRTIYKYIDASQMATCQLQMGYTVLEPGSSWNTMPAHTHARRMETYMYFDFAEPDTRVLHLLGEPTETRHIALFNEQAVVNPSWSIHCGVGTTNYAFIWAMCGENQTYDDMDQVPMNELR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: TIG_CLAMS
Sequence: MKTTVEKLSPTRVKLAISATPEDLKPHIDHAYGHIAEQVAIPGFRKGKVPPPIIDQRVGREAVLEHAVNDGMDGFYQAAVKETDIRPLGRPEADVKEWPGKDLTGDLLLEIEVDVRPEFDLPAYEGLELTVDSVEVTDDEVATELDSLRSRFGTLITVDRPAKTGDFVQIDLTATIAGNAVDTASGISYELGSGDLIDGIDEALESLTAGESTTFESKLLGGDNEGETAEIAVTVQSVKERELPEADDDFAQIASEFDTIDELRADLKVQVGKSKVFGQVTQARDQIVDKLLEGVEIPVPEKLVEDEVQRHLENENRLEDDVHRAEVKESSEKAFRQQLLLDVIAEKEELKVSQDELTQYLIQGAQQYNMEPNEFVQVLQQNNQIPAMVGEVARNKALAVVLDKAKVVDADGKVVDVTEFTQPVVRDADAPVEEPADADAEAVVADAPAEEAVAEEAPAEKPKKKAPAKKKAAEKAADSE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ATPL_RICAH
Sequence: MDMVSLKFIGIGLMAIGIYGAALGVSNIFSSLLSSIARNPSAAENLQRMALIGAGLAEAMGLFSFVIAMLLIFS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CATB_PONAB
Sequence: MWQLWASLCCLLALADARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDVSYLKKLCGTFLGGPKPPQRVMFTEDLKLPESFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSERDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
What is the function of this protein?
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity).  Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity).  Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity).  Has also been implicated in tumor invasion and metastasis (By similarity).
What are the official names of this protein?
Cathepsin B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells.
Protein: OBG_LIMRD
Sequence: MNMFVDQIKIEVHAGKGGDGMVAFRREKYVPNGGPAGGDGGRGGSIILKVDEGLRTLMDFRYHRIFKAKNGGNGMSKQMTGPSAEDTIIAVPQGTTVRDLDTGKIIGDLVEKDQELVVAKGGRGGRGNIHFASAKNPAPEIAENGEPGEDHYLELELKMLADVGLIGFPSVGKSTLLSVVTGAKPKIAAYEFTTLTPNLGMVMLPDGRDFAMADMPGLIEGASKGIGLGLKFLRHIERTRVLLHLVDMSSEDPHQAIERYRQINKELADYDPELLKRPQIVVATKMDLPNSADNLAAFKADLAADKTLEKQPEIFPISAVTHQGVQQLMQLTADLLDKTPAFDSESHDKELVAEYRAAAPDKKDEADFTITKDEDGTWVLGGEKLIRLFKMTDLTHEESQLRFARQLRHMGVDDALRAKGVQDGDLVRIEKFVFEFIQ
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_MYCS5
Sequence: MAKDVQKVAKLQFLAGKAKPGPSLAGVGVNMPEFTKAFNDATRDRGDEPVPVQITVFKDKTFEFKLFTAPASYKIKQAAKIQSGSKNAKTTIAGTITLEQLKEIAEYKLPDLNTDDVNAAMAIVAGTAKQMGVLVEGYDDVAKAKQAAIEAAKAESLAKAKKESLKSQEEELKASKGKAIDVNVIEKEREEKE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: GLMU_YERP3
Sequence: MSNSSMSVVILAAGKGTRMYSDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELLKKTLADPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILMLYGDVPLISVDTLQRLLAAKPEGGIGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGILVANGRDLKRWLSLLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQLSALERVFQTEQAEKLLLAGVMLLDPSRFDLRGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGDDSEISPYTVLEDARLDANCTVGPFARLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLSYLGDAEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVANGATIGAGTTVTRDVAENELVISRVKQVHIQGWKRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIP_WEICA
Sequence: MYTEGFIDVTGGRVSFQKFDENGGGTPVIVLHGGPGSSCYSLLGLKALAKDRPVILYDQLGCGKSDRPMDTTLWRLDRFVEELAQIRQALNLDEVHILGHSWGTTLAAAYCLTKPSGVKSVIFSSPCLSAPLWEQDQKRNLKKLPLDVQETINRCEENGTTDSEEFAAAIEVFGKHFVNRLEKQPEWLEQKPSGYRNADIYNIMWGPSEFTVLGNLKNFDCTTQLKEITCPSLYTCGRFDEATPETTEYYSSLTPKSKFHVFEKSAHMPYIEEPEEYLAVIGDFLNSI
What is the function of this protein?
Releases the N-terminal proline from various substrates including at least dipeptides Pro-Pro, Pro-Gln, Pro-Trp and Pro-Tyr.  Acts also on amides (Pro-beta NA) and oligopeptides including Pro-Leu-GlyNH2, Pro-Leu-Gly, Pro-Phe-Gly-Lys, Pro-Pro-Ala-OBut and Pro-Pro-Gly-(Pro-Pro-Gly)(4).  Higher activity toward small peptides (up to three residues), but very low activity for longer peptides.  Has no activity against p-nitrophenyl acetate, poly_L-proline, Met-Pro or amino acyl amides other than Pro-betaNA (Pyr-betaNA, Phe-betaNA, Cys-betaNA, Met-betaNA, Leu-betaNA, Ala-betaNA and Z-Gly-Pro-betaNA).
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRB_PHOTE
Sequence: MKAPILKKLALISVLSLACTSWVHAAERIAFIPKLVGVGFFTSGGQGAVAAGKTLGVSVTYDGPTEPSVAGQVQLINNFVNQGYDAIVVSAVSPEGLCPALKRAMKRGVKILTWDSDTSPECRSIYINQGTPNQLGGMLVDMTANQVKKEQAKVAFFYSSPTVTDQNQWVXQAKDKIAAEHPGWEIVTTQFGYNDATKSLQTAEGILNAWSDLDAIIAPDANALPAAAQAAENLKRQDVAIVGFSTPNVMRPYLERGTVKQFGLWDVVSQGKISIHVANELLRKGDLNVGDKLDIPDIGTVAVAPNSIQGYSYEAKGNGIVVLPERVIFTKDNINQYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RPIA_MARN8
Sequence: MTQDELKQAVAKAAVDHIAPHLEPSSIVGVGTGSTANFFIDYLAEYRNDFDGAVASSEATAERLKKHGIPVYDLNAVNEIEFYVDGADETNESLELIKGGGGALTREKIVAAVAKTFICIADESKQVGILGEFPLPVEVIPMARSHVGREIVKLGGDPVYRDGFVTDNGNIIIDIHNMDISRPLVVEEKLNNIVGVVTNGLFARRPADLLLLGTRDGVKSIARGA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: GLND_PSESM
Sequence: MPQVDPDLFDRGQFQAELALKASPIAAFKKAIRRARDVLDNRFRSGRDIRRLIEDRAWFVDNILQQAWDQFEWSEDADIALLAVGGYGRGELHPYSDIDLLILLESDDHEVFREPIERFLTLLWDIGLEVGQSVRSVDECAQEGRADLTVITNLMESRTIAGPEHLRQRMLEVTSTQHMWPSKEFFLAKHAEQKKRHHKYNDTEYNLEPNVKGSPGGLRDIQTILWVARRQYGTLNLHALAGEGFLLGSENALLASSQEFLWKVRYALHMLAGRSEDRLLFDYQVRIAGLLGYEDNDAKLAIERFMQKYYRVVMSIAELSDLIIQHFEEVILSDDDGTPQPINSRFQLHDGYIEATNPNVFRRTPFAMLEIFVLMAQHPEIKGVRADTIRLLREHRHLINDDFRNDIRNTSLFIELFKCEIGIHRNLRRMNRYGILGLYLPEFGHIVGQMQHDLFHIYTVDAHTLNLIKHLRKLQYTEVSEKFPLASKIMARLPKPELIYLAGLYHDIGKGRGGDHSELGAVDAQAFGTRHHLPAWDNRLIVWLVSNHLVMSTTAQRKDLSDPQVIHDFAQFVGDEVHLDYLYVLTVADINATNPTLWNSWRASLLRQLYTETKRALRRGLENPVDREEQIRRTQTAALDILVRSGTDPDDVEQLWSALGDDYFLRHTAGDVAWHSDAILQQPADGGPLVLIKETTQREFEGGTQIFIYAPDQHDFFAVTVAAMDQLNLNIHDARIITSSSQFTLDTYIVLDHEGGSIGNNPERIQDIRDGLTEALRNPDDYPTIIKRRVPRQLKHFAFAPQVTIHNDAQRPVTVLELLAPDRPGLLARIGKIFLEFDLSLQNAKIATLGERVEDVFFITDANNQPLSDPQLCSQLQEAIVKQLSVNSEPGGDLRISI
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.