PharMolix/UniProtQA huggingface dataset:
Protein: Y4555_XANOP
Sequence: MSRVKKLHQWKERLRDRARTVSFGRFLWRRFLDDRLFQAAASLAYTTVFALVPLAIVVFGVLSAFPAFNEWKDALTDFIFTNFVPGAARSVQNYLNRSLEDLGKFTVAGMVALVASLLITLHSIEQTFNSIWRVAAARPKVTRFLIYWTVLTLGTMLAAASMAMAAYVFALPLFRTTEGQWLAEFAWRLAPMAVEFICIVLIYRVVPQHVVRLRHALPGALLAVILMEIVKWGFGVYLGNFQTYQRIYGALSALPILLLWIYLSWVSVLLGASLASSMAAFRYQPEAMRLPTGFEIYGLLRLLGRFRQARIHGEGLDEDRILALEPMLTDTLMQELLCELKRMRLLRRDERGQWLLARDLDLVPLAELYENCQLRVPIEDRPLPCRDDAYGQAAAAALEQLRQPLRSVLAQPVGDLYTHLPGDPP
What are the official names of this protein?
UPF0761 membrane protein PXO_04555.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PETG_OLTVI
Sequence: MVEPLLSGIVLGLVPVTLAGLFVTAYLQYRRGDV
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: S39AD_BOVIN
Sequence: MPGCPCPGIGMAGQRLLFLAALALELLGGAGGSQQALRSRGVAAACRLDSKESESWGALLSGERLETWICSLLGSLMVGLSGVFPLLVIPLEMGTTLRSEAGARRLKQLLSFALGGLLGNVFLHLLPEAWAYTNSASSGGERQSLQQQQQLGLWVIAGFLTFLVLEKLFFDSKGKEETSQAPSKDPAAAAALNGGHYLAQPAAEPGPSAVVRNIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGACFAICAQSPKGVGTGVGVVAVRRGALAEGHGRPDPGIRARLCSGPPRGMGGGRYTWPPSPPQPVRAPPPATEETVAWILPFTSGGFLYIALVNVLPDLLEEDDPWRSLQQVLLLCAGIVVMVLFSVFVE
What is the function of this protein?
Functions as a zinc transporter transporting Zn(2+) from the Golgi apparatus to the cytosol and thus influences the zinc level at least in areas of the cytosol.  May regulate beige adipocyte differentiation.
What are the official names of this protein?
Zinc transporter ZIP13, Solute carrier family 39 member 13, Zrt- and Irt-like protein 13, ZIP-13.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: DGGGP_HALSA
Sequence: METGRGLVELARPVNTLAAGALTFIGAFVAGGAVGRPAATGAAVGATWLATAGGNAINDYFDREVDRINDPDRAIPRGAVSPRGALAYSVVLFVGAAALAATLPVLAVCIAALNLAGLLTYTQYLKGRPGAGNALVAYLGGSTFVFGAAAVGSPLAGGVLAALAALSTFAREVIKDVEDLAGDRAAGLRTLPVVVGHQRALAVSAVFVVGAAAASPVPYLVGVFGWWYLVAVCPGVVVMVVAAARSYTDPAAGQRLLKRGQLLAAAAFVVGRLVTP
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP).  This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Digeranylgeranylglyceryl phosphate synthase, DGGGP synthase, DGGGPS, (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, Geranylgeranylglycerol-phosphate geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS28_THEAC
Sequence: MPNEATPAEVVEIIGRTGMTGEATTVKVRVLAGRDQGRIIARNVLGPVRVGDILMLMETAREAKKLSIR
What are the official names of this protein?
30S ribosomal protein S28e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: MAO2_ECOLI
Sequence: MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVAAPCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFAGIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFHDDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVVCDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKKMARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDVGATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKIAPAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEGEEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFKEYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDYHEHFSVVKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFGIEPRVALLSHSNFGSSDCPSSSKMRQALELVRERAPELMIDGEMHGDAALVEAIRNDRMPDSSLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASVRRIVNMVALAVVEAQTQPL
What is the function of this protein?
Catalyzes the decarboxylation of malate to pyruvate (PubMed:17557829).  In vitro, shows malolactic enzyme activity in the presence of NADPH.  However, it is unlikely that this activity is of relevance in E. coli, which produces little NADPH (PubMed:33824210).
What are the official names of this protein?
NADP-dependent malic enzyme, NADP-ME.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
Protein: RL36_MARN8
Sequence: MKVRASVKKICRNCKVIRRNGSVRVICSEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SYG_LACE2
Sequence: MEKTMEKIVSLAKARGFVYPGSEIYGGLANTWDYGNLGVELKNNVKKAWWQKFVQESPYNVGVDCAILMNPQTWVASGHLGGFSDPLMDCKECHERFRADKLIEDWADENSYDLGGSVDGWTQEQMKNFIDEKNICCPSCGKHNFTDIRQFNLMFKTFQGVTEDAKNTVYLRPETAQGIFVNFKNVQRTSRKKVPFGIGQIGKSFRNEITPGNFTFRTREFEQMELEFFCKPGTDLEWFTYWRQYCIDWLKALGIKEDEMRARDHSPEELCFYSKGTTDIEFLFPFGWGELWGIADRTDYDLTQHQTVSGEDMSYFDDEAKEKYIPYVIEPSLGADRVTLAFLCSAYDEEELEGGDVRTVLHFHPAIAPVKIGILPLSKKLNEGAEKVYAELSKYYNCEFDDRGNIGKRYRRQDEIGTPFCITYDFDSEEDGAVTVRDRDTMQQERIKIADLKAYFEDKFRF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_SYNWW
Sequence: MIKNTFSRKKYFALSRRMEKEEEEKKVALPINCPSCSARIAAEALQRNLKVCPKCQHHFSLSARERIDLMVDKDSFQEFDADLSSFNLLDFPGYQEKLEKAQELSGSREGIITGLASIDGHKLVLGVMESGFMMASMGSVVGEKVCRAVEQAMELSCPLLICSCSGGARMQEGMVALMQMAKTSAVLGKFNQAGLLYISLLTHPTTGGVSASFASLADIILAEPGALIGFAGPRVIKQTIGQQLPPRFQRSEFLLEHGMIDLLVERSQLKATLSSLLGLHQG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_COLP3
Sequence: MSTGKFIVIEGMEGAGKSSAIAVIESTLNKHGIEYINTREPGGTPLAESLRDMVKSVDHQEKLTVETELLLMYASRSQLLANKILPALAAGKWVIGDRHDLSSRAYQGGGRGFDETIMNTISDITLKGFRPDITLYLDIDPHIGLSRAKARGDLDRIELEKMEFFIRVHNKYRELAEQDDSIITVDAAQAMLKVHQDVEKAVIGFITNTDKG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ORC1_MOUSE
Sequence: MPSYLTRQKTRQTFSWVGRPLPNRKQFQQMYREICMKINDGSEIHIKVGQFVLIQGEDNKKPYVAKLIELFQNGAEVPPKKCARVQWFVRFLEIPVSKRHLLGRSPPAQEIFWYDCSDWDNKINVETIIGPVQVVALAPEEVIPVDQKSEETLFVKLSWNKKDFAPLPPEVLAALREQEDSPEWQKPLKAKIKNVKSPARNTTEQEVKGIKSNHSTSKFHQTPANIVIPNAKKSLELDGLGFTRKPNTRWSKKSSCDSLDYQKTSKRRAAFSETTSPPKKPNKPREIKPSSALETRVKNGQTQPFCAKSSVVLRARNPAMTTTKLGVDNTLSPIRNGLRSSVVPSGGLTPVYIRRKAKEQETHKEPIRTSRVHRKSSLLTLKRIRQQLCLLDGDDRDQEEEESVDSESEEEDEFISSLPTRNSLGQSRTRQTPSKSPQKNPKPRTPHRATPQIRDRNLAVQEPASALEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGKTATVHEVIRCLQQAAETDDVPPFQYVEVNGMKLTEPHQVYVQILKKLTGQKATANHAAELLAKQFCGQGSQKETTVLLVDELDLLWTHKQDVMYNLFDWPTHKGAHLIVLTIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHSQLKQILVSRLRNLRAFEDDAIQLVARKVAALSGDARRCLDICRRATEICELSHLRGDSLSLVTVAHLMEAIDEMFSSSYITAIKNSSVVEQSFLRAIIAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSRLGSCRLLLVEPSRNDLLLRVRLNVSQNDVLFALKEE
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ORC1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPA_UREPA
Sequence: MANFISLKKNEDILDTIKKQQKIHSNQIVVYFRKTNLKNVRLAISISKKKFKLATQRNRIRRLIKAWFIAADIPIKSYDIVVLVKPSFIDGSFVLNCNNLKIILQRIINKEKR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: SPL10_ORYSJ
Sequence: MMSGRMNAAGDESPFPFGAMQAPGPGAYVGFDHGAAAVAAAAAAAQRAGMLQHHHHHMYDGLDFAAAMQFGGGQDAPPHPQLLALPPSMAAPPPPPMPMPLQMPMTMPMPGDVYPALGIVKREGGGGGQDAAAGRIGLNLGRRTYFSPGDMLAVDRLLMRSRLGGVFGLGFGGAHHQPPRCQAEGCKADLSGAKHYHRRHKVCEYHAKASVVAASGKQQRFCQQCSRFHVLTEFDEAKRSCRKRLAEHNRRRRKPAAAATTAVAAAKDAAAAPVAAGKKPSGGAATSYTGDNKNVVSMSAAKSPISSNTSVISCLPEQGKHAAAAARPTALTLGGAPPHESSAPQIGAMLHHHHHHQQDHMQVSSLVHINGGGGGGSNNILSCSSVCSSALPSTATNGEVSDQNNDNSHNNGGNNNNMHLFEVDFM
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'.
What are the official names of this protein?
Squamosa promoter-binding-like protein 10.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSRK_SALCH
Sequence: MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIPATAIAAVSACSMRESIVIYDSNGEPIWACANVDARAAHEVSELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDIYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCDLQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAYGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGIWPSLAETGEKLVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISAA_STAAB
Sequence: MKKTIMASSLAVALGVTGYAASTGHEAHAAEMNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLSAWGF
What is the function of this protein?
Is able to cleave peptidoglycan.
What are the official names of this protein?
Probable transglycosylase IsaA, Immunodominant staphylococcal antigen A.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. IsaA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GPD_COLGL
Sequence: MASLGADKKHKVTVVGSGNWGSTICKIVAENTKANPDLFEEAVHMWVFEEDVVIDKSSPYYDPAVGDAPQKLTGVINKYHENTKYLPGIKLPDNIIANPSLQDAVKDSTILVFNLPHQFIGNVCKQLRGHIMPFARGISCIKGVNVSDDGISLFSEWIGDGLGIYCGALSGANIASEIAAEKWSETTIAYDPPPMDNSRAPTPRSNSPANGNGIAPLTPVEMQHKDARGRTSKTKLTPVPAEYPPLDHQIFKQLFHRPYFHVRMVSDVAGVSLGGALKNIVALAAGFVDGRGWGDNAKAAIMRVGLLEMVNFGKEFFGQTVHTGTFTEESAGVADLITSCSGGRNFRCAKMAVAEGLSVEEIEKRELNGQLLQGTSTAKEVNSFLKARGLEKDYPLFTAVHGILEGRHSVDDIPSLVSDS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Protein: TAM_MYCBO
Sequence: MWDPDVYLAFSGHRNRPFYELVSRVGLERARRVVDLGCGPGHLTRYLARRWPGAVIEALDSSPEMVAAAAERGIDATTGDLRDWKPKPDTDVVVSNAALHWVPEHSDLLVRWVDELAPGSWIAVQIPGNFETPSHAAVRALARREPYAKLMRDIPFRVGAVVQSPAYYAELLMDTGCKVDVWETTYLHQLTGEHPVLDWITGSALVPVRERLSDESWQQFRQELIPLLNDAYPPRADGSTIFPFRRLFMVAEVGGARRSGG
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Probable trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_ECO5E
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_BURCM
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTAGGRKVINARRAKGRKRLAI
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CYB_BASAS
Sequence: MTNIRKTHPLAKIINNSFIDLPAPSNISAWWNFGSLLGICLLLQIATGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYTFSETWNVGIVLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGATLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAMIHLLFLHETGSNNPSGMTSESDKIPFHPYYTIKDILGILLLIFILMGLVLFMPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIIPFLHTSKQRSMTFRPLSQCLFWLLVADLLVLTWIGGQPVEYPFITIGQLASILYFMILLVLMPTTSIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MTA1_NOSS1
Sequence: MTSFELESPIEIKTDPTDLDQESDSFVQEISRFNKALEQRFRDKMRLHESLSRKIVSFQANKSKPQYRWFKYKEAFSVDLVNQLIFEYEKKSFERILDPFAGAGTMLFACSDAGIQADGIEVLPIGQEIIEVRKIIQRQFRREDFLRLIEWYKQKPWNQHNNRKYLNRLRITDGAYPPETEASIERFLFSIEKENILVKQVLRFALLCILESISYTRKDGQYLRWDKRAFRKSGSDKFDKGKILDFDEAITEQIKLILNDSFDLISNTLFCYGTQRSGINLFNASCLKILPEFEQDFYDCIITSPPYCNRYDYTRTYALELALLGVGERDIVQLRQDMLSCTVENKEKSLIHNWQEALRILDKQELLQSILRFLERELERKKLNNNGIPRMIKGYFYEMACVIIECFRVLKNGSPLFMVNDNVRYAGIDISVDLILSNIAEEIGFNVEKILVLPTGKGNSSQQMGTHGRKTLRKCVYVWRKP
What is the function of this protein?
An alpha subtype methylase that recognizes the double-stranded sequence 5'-CYCGRG-3', methylates C-1 on both strands, and protects the DNA from cleavage by the AvaI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.AvaI, M.AvaI, Modification methylase AvaI, N(4) cytosine-specific methyltransferase AvaI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
Protein: TXF2A_SCODE
Sequence: MKMVYLGLFLIITSCVISSGNLIYECKWADSIRLKDKNPTHEFCKKKCEEKNTDRITVQHGFHSSDYRCTCQGEKILETPYQSDGVKDCHRI
What is the function of this protein?
Inhibits voltage-gated potassium channels (Kv) (IC(50)=about 10 nM), when tested on DRG neurons.
What are the official names of this protein?
Kappa-scoloptoxin(15)-Ssd2a, Kappa-SLPTX(15)-Ssd2a, Toxin SSD559.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-15 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LRWD1_XENLA
Sequence: MTKLTTELLLKKGLPKCSHLKDLKKLNLSKMQLDLKDLDQKLFSQMVNLDELDISHNTLSDLPGNLRLHNLRILNFADNHVEDVTVLKQFPNLEEVIYEDNIYLTVSDNYKVFCLLPKLRRLNNKDITSLANHVRFVNHRELSNRVEAYWESKYKDKLPDKPPSQKINAVAKDFIKAVVDNVRYGPSSLKDFVRWKVEMIARNLIFSLSNDPKKDTDPVLQTSEDTAVENSSKKRESADECTEGSPTKRPRIQIDLQSMPLSPRKSSRLQNSPLCLTPTKRKQETSAQGTPSKFIETKSPKIALKTTPSKKHTNELSAKITGKPKLPLTPKKIHKALDNIEPLHFLQCHSKNNSCEDFKTQLWACAFEPNLDSSCPKAVATCGGDSICIIDCETGKVMKKYKVTGEEFFTLVWTTLTMIGKDGQKRKINVLAAGGKYGVVRMIHAKGSLCYGEIKAHKKAISIMCFSPKQETFLFTGSYDKRIILWDIGVPDCDYNFRPSQLLTLDTTSVPLRMCVVPSCPDEFLVAACEDGCFAWDIGLDKKQGRRSHEVEFNFPLYKEERKDKCFHIIDSLAFLNEDIIASKSVMQGSIYLWSWEKTLKSRKNKNVKKLDAVILSQMKWSSSETPYLVLSTSPERDCVFCGDEDGKIWIYDLDSCKADLQRGKLCSTVKEPTKILSWPLLCSQKEKTVDKTLINVVTVDPTMEYLVALTDINIVSIWKIQ
What is the function of this protein?
Required for G1/S transition.  Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells.  Binds a combination of DNA and histone methylation repressive marks on heterochromatin.  Required for silencing of major satellite repeats.  May be important ORC2, ORC3 and ORC4 stability (By similarity).
What are the official names of this protein?
Leucine-rich repeat and WD repeat-containing protein 1, ORC-associated protein, ORCA, Origin recognition complex-associated protein.
What is the protein family that this protein belongs to?
Belongs to the LRWD1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, telomere. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore.
Protein: GATB_STREM
Sequence: MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSFPGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNSFSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPDLPLFEIDDAWIEDMRAELPRFPAERRVSYIKDLGLSAYDAGQLTATKALSDFFEQAVALGGDAKQVSNWLQGEVAQFLNAEGKTIDQLALTPDSLVEMIAIIADGTISSKIAKKVFVHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQIAQQLLAQELQKLLD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: Y1471_AZOSB
Sequence: MDARLLEILVCPLCKGPLDYLKDKQELVCKADRLAFPIRDGIPVMLEEEARALAAEDVDALR
What are the official names of this protein?
UPF0434 protein azo1471.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: Y4008_BACC1
Sequence: MEYQYPLDYDWSNEEMVTIVKFYEAIEKAYEKGIVREELMGLYRRFKEIVPSKAEEKKIDKEFQEVSGYSIYRAIQKAKEIEEEKLVKM
What are the official names of this protein?
UPF0223 protein BCE_4008.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: LARC_MOOTA
Sequence: MKIAYFDCFSGISGDMCLGALIACGLSQDELTSGLKGLGLEGWELRVREVKQHSIAATDVAVQVTGSQPHRHLADILGLINNSSLPAPVKEKSAAVFKNLARAEGQVHGIDASQVHFHEVGAVDAIIDIVGSILGLHLLGIEKVISSPLPAGSGWVDCRHGKLPVPAPATLYLLQGYPVYGTEDKAELVTPTGAALITTLADSFGPFPAMNLTRVGFGAGKTELPHPNLLRLALGEINSGQLEGEESSLVIETTIDDMNPEFFPALLEETMAAGAVDAFFTPVQMKKGRPGILFTALCPENKLAAVAAAIFTHSSTLGLRFRRDQRLVCQRRMAEVVTPYGTVPVKLGLYRDPTGQVITNIAPEYESCRQIAKSAGAPLKEVYAAALAAARALKAF
What is the function of this protein?
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex).  Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor.  Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.
What are the official names of this protein?
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, P2TMN nickel insertion protein, Nickel-pincer cofactor biosynthesis protein LarC.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: RL15_SHIBS
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: H2A3_ARATH
Sequence: MAGRGKQLGSGAAKKSTSRSSKAGLQFPVGRIARFLKAGKYAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIVPRHIQLAVRNDEELSKLLGDVTIANGGVMPNIHNLLLPKKAGSSKPTEED
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2A.3, HTA2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NUSB_STAAC
Sequence: MSRKESRVQAFQTLFQLEMKDSDLTINEAISFIKDDNPDLDFEFIHWLVSGVKDHEPVLDETISPYLKDWTIARLLKTDRIILRMATYEILHSDTPAKVVMNEAVELTKQFSDDDHYKFINGVLSNIKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.