PharMolix/UniProtQA huggingface dataset:
Protein: FAD1_SIGCA
Sequence: MGGGGQPRESGEPGSSPAVYTWEEVQHHSSRNDQWLVIDRKVYNISQWAKRHPGGYRVIGHYAGEDATEAFTAFHPDLKFVQKFLKPLLIGELAATEPSQDRNKNAALIQDFHTLRQQAESEGLFQARPLFFLLHLGHILLLEALALLMVWHWGTGWLQTLLCAVMLATAQSQAGWLQHDFGHLSVFKKSRWNHLVHHFVIGHLKGASANWWNHRHFQHHAKPNIFKKDPDINMVDLFVLGETQPVEYGVKKIKLMPYNHQHQYFHLIGPPLLIPVFFHYQLLKIMISHRYWLDLVWCLSFYLRYMCCYVPVYGLFGSVVLIVFTRFLESHWFVWVTQMNHLPMDINYENHNDWLSMQLQATCNVEQSLFNDWFSGHLNFQIEHHLFPTMPRHNYHLVVPRVRALCEKHEIPYQVKTLPQAFADIIRSLKNSGELWLDAYLHK
What is the function of this protein?
Fatty acid desaturase with bifunctional delta-5 and delta-6 activities.  Component of a lipid metabolic pathway that catalyzes the biosynthesis of polyunsaturated fatty acids (PUFA) with preference toward n-3 substrates and Delta(6)function.
What are the official names of this protein?
Acyl-CoA Delta-6 desaturase, Delta-6 desaturase, Delta(5)/Delta(6) fatty acid desaturase, D5D/D6D fatty acid desaturase, Delta-5/Delta-6 fatty acid desaturase, FAD1, Linoleoyl-CoA desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRMD_BURMA
Sequence: MDEATQSAIQFDVVTLFPEMFRALTDWGITSRAVKQGRFGLRTWNPRDFTTDNYRTVDDRPYGGGPGMVMLAKPLEAAIGAAKAAQAAQGVATSRVVMMSPQGAPLTHERVARMAAEPGVVLLCGRYEAIDQRLIDRCVDEELSLGDFVLSGGELPAMALMDAVVRLLPGVLNDAQSAVQDSFADGLLDCPHYTRPEEYEGVRVPDVLLGGHHAEIERWRRQEALRNTIAKRPDLIARARREKLLSRADEAWLASLAKEAKQAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_PSEU2
Sequence: MSQVNRRKVLFVTSELADLVKTGGLGDVSAALPRAMRHLHDVRVLIPGYPQVINSGNPIHIISQLGGHAALPPCKVGRMDMKDGLVIYVLICPELYEREGTPYADSNGRDWSDNHIRFARLGLAAAEFAAGEVKSQWCPELVHAHDWPAGLAPAYMRWRGQSTPSIFTVHNLAYQGTVSTASSRELGIPDSAITPEGMEFYGQLSFIKAGMAFASHITTVSATYAREITTPEFGCGLEGFLQSKANKGQLSGIPNGIDESWDAATDEHLICHFAPNEWTRKEINADYVRELFELDASTGPLFAVVSRLVYQKGLDLTIGVAEHIVNNGGQIAIIGRGEPEEEEAMRELAARFPGRVGVRIGFNETDARRMFAGSDFLLMPSRYEPCGLSQMYAQRFGSLPVARNTGGLADTIEDGVTGFLFNESTVESYTQALDRAFQVFAHPELLNAMRCRAMAAPFNWHQAVEPYADLYRDLLKKNVSVSSNY
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: LCL3_ASPCL
Sequence: MRWPPWASESQAQQHNTKPPIEHNEKEHGSKSKSWESSVTAIDWAAFAEPRTIIPTVILTSGFLGAFHIHRRYLRRFPDAGSITPSHFRRRSLLGRVTSVGDGDNFRLYHTPGGRLAGWGWLPWKKVPTSKKELRDKTVHIRLAGVDAPELAHFGRPEQPFAREAHQWLTSYLLNRRVRAYIHRPDQYQRAVATVYVRRALDFPIPFRRRDVSYEMLKQGLATVYEAKWGAEFGGEAMERKYRKAEWWAKLRGTGLWKDFRRNEKEWESPRAYKTRMGLEEAVQPRVESKK
What are the official names of this protein?
Probable endonuclease lcl3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: YOBA_SHIFL
Sequence: MASTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAAPQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYTVDWHVVSVDGHKTKGHYTFSVK
What are the official names of this protein?
Protein YobA.
What is the protein family that this protein belongs to?
Belongs to the CopC family.
What are the subcellular locations of this protein?
Periplasm.
Protein: THIC_ACIF5
Sequence: MATRPTDMVNTMQDAAVTCGPIPGSHKRYLGGVRFPELRIPLREIRQSDSRKRDGSLEVNPAIPVYDCSGPYTDPDVVIDIHAGLPAMRWQWSPTDTAIESRPEPGSAYGRARLADVRTADLRFHHRREIRRAANGGNVSQMHYARRGIITPEMEFVAIRENQGLEHLRASHPALFRAHRGESFGAQIPDTITPEFVRDEIARGRAIIPANINHPELEPMIIGRNFLVKINANIGNSAVTSSIAEEVEKMVWSIRWGADTVMDLSTGRHIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYIPLTANRLTGIVSRGGSIMAKWCLAHHQESFLYTHFEEICEIMKAYDVSFSLGDGLRPGSLADANDEAQFAELHTLGELTRIAWKHDVQVMIEGPGHVPMQLIKANMEEELQHCFEAPFYTLGPLTTDIAPGYDHITSAIGAAQIGWYGTAMLCYVTPKEHLGLPDKNDVREGAITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFHLGLDPEKAREYHDETLPQEGAKAAHFCSMCGPHFCSMKISQDLQEYAQSKGEDIETARLEGLQEKAEDFKRLGKNIYLR
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CLD7_RAT
Sequence: MANSGLQLLGFSMAMLGWVGLIASTAIPQWQMSSYAGDNIITAQAMYKGLWMECVTQSTGMMSCKMYDSVLALPAATQATRALMIVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMTGGIIFIVAGLAALVACSWIGHQIVTDFYNPLTPMNIKYEFGPAIFIGWAGSALVLLGGALLSCSCPGSESKAAYRAPRSYPKSNSSKEYV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space.
What are the official names of this protein?
Claudin-7.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane. Cell junction, tight junction. Note=Colocalizes with EPCAM at the basolateral cell membrane and tight junction.
Protein: Y465_MYCPN
Sequence: MAFLFISNEWKYQQLIFKINCWHFCYYPKNYLGGSILSKRLFIPPSACRIDLSVFPWAFICSPWNFCSTWSSLICSPCFSTVWVSLLICSPWRSTTWTNWLICSPCFSTVWVNLLICSPWAAKVVSIFVSRWLFEFLYSLNSLRVTYSVFTGITGLLSLNCLLNLPENSTLLFSGLMMYQPEKVPFLVFFTMSWNSFSL
What are the official names of this protein?
Uncharacterized protein MPN_465.
What is the protein family that this protein belongs to?
To M.pneumoniae MPN_037.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4670_RHOPT
Sequence: MATSAAAVQEDPATNFAKDQLRAIIERIERLEEEKKTISDDIRDVYAEAKGNGFDVKALRTIVRMRKQDANERAEQETILETYMQALGML
What are the official names of this protein?
UPF0335 protein Rpal_4670.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: O364_CONTS
Sequence: MSGLGIMVLTLLLLVFMATSHQDAGEKQATQRDAINVRRRRSITRRVDEECNEYCDDRNKECCGRTNGHPRCANVCFG
What are the official names of this protein?
Conotoxin TsMSGL-11.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATAT_MOUSE
Sequence: MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIVDELGKASAKAQHLPAPITSALRMQSNRHVIYILKDTSARPAGKGAIIGFLKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQHMLQKERVEPHQLAIDRPSPKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRPPTSSLRATRHSRAAVADPIPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPDRGPLRPFVPEQELLRSLRLCPPHPTARLLLATDPGGSPAQRRRTRGTPWGLVAQSCHYSRHGGFNTSFLGTGNQERKQGEQEAEDRSASEDRVLLLDGSGEEPTQTGAPRAQAPPPQSWTVGGDIMNARVIRNLQERRSTRPW
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.  Required for normal sperm flagellar function.  Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells.  May facilitate primary cilium assembly.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase 1, Alpha-TAT, Alpha-TAT1, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane, clathrin-coated pit. Cell junction, focal adhesion. Cell projection, axon. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=In primary root dorsal ganglion neurons, localizes with acetylated tubulin in axons. Recruited to the mitotic spindle during cell division.
Protein: NADD_MYCTU
Sequence: MGVMGGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASNPRFSVSRVDIDRGGPTYTKDTLADLHALHPDSELYFTTGADALASIMSWQGWEELFELARFVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISSTDCRQRAEQSRPLWYLMPDGVVQYVSKCRLYCGACDAGARSTTSLAAGNGL
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: TMX4_HUMAN
Sequence: MAGGRCGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLVFGLFMGLVLVVISECFYVPLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADKGL
What are the official names of this protein?
Thioredoxin-related transmembrane protein 4, Thioredoxin domain-containing protein 13.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass type I membrane protein.
Protein: RBFA_PASMU
Sequence: MAREFKRSDRVAQEIQKEIAVILQREVKDPRIGMVTVSDVEVSSDLAYAKVFVTFLFDNDESAIDAGMKGLEKASPYIRSLLGKAMRLRIVPEIRFIYDRSLIEGMRMSNLVSNVIREDNARHIDDDVSEEK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 7UP1_DROME
Sequence: MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMHGQYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYGQCMQPNNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTDACGLSDVTHIESLQEKSQCALEEYCRTQYPNQPTRFGKLLLRLPSLRTVSSQVIEQLFFVRLVGKTPIETLIRDMLLSGNSFSWPYLPSM
What is the function of this protein?
Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC-2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs).
What are the official names of this protein?
Steroid receptor seven-up, isoforms B/C, Nuclear receptor subfamily 2 group F member 3, isoforms B/C.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: VSP_PHIOL
Sequence: MALIGVLANLLILCLSYARTAPDRIIGGLECNQNEHRSLVLLYNSGGFFCSGTLINHEWVLTAAHCNRENIQIKLGVHNIHVPNEDEQIRVPKEKVCCLGTMNCTQWNQDIMLIRLNSSVNYSTHIAPLSLPSNPPSVGSVCRVMGWGTITSPEVTYPEVPHCVNIQILHKELCEAAYPILLGNSNILCAGKLLGDKDSCKGDSGGPLICNGQIQGIVSWGGFPCAQILEPGVYTKVFDYIDWIQDIMAGNANVICPGDNF
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SECP_VESMG
Sequence: MKNYSKNATYLITVLLFSFVAMLLIIPSKCEAVSNDMQPLEARSADLVPEPRYIIDVPPRCPPGSKFIKNRCRVIVP
What is the function of this protein?
Nontoxic peptide.
What are the official names of this protein?
Secapin.
What is the protein family that this protein belongs to?
Belongs to the secapin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARHG4_HUMAN
Sequence: MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPHRSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTAMPDGALDTAVCADEVGSEEDLYDDLHSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDDAPLAGNSGAEDGGAEAQSSKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFSEEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKPSTFWHSISRLAPFRK
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases.  Binding of APC may activate RAC1 GEF activity.  The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion.  Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells.  Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1, Asef, Asef1.
What are the subcellular locations of this protein?
[Isoform 3]: Cytoplasm. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with membrane ruffles.
Protein: FLGI_NITEU
Sequence: MTLSKWILSFGLSVCLIVSHPVSAERIKDLANIQGVRANQLIGYGLVVGLDGTGDQTQQTPFTVQSILSMLGQLGVNLPPGTNLQLRNVASVMVTATLPAFAKPGQQIDVTVSSMGNAKSLRGGTLLMTPLKGIDNQVYAVAQGSLVIGGAGASSAGSSVQINHLGAGRISAGAIVERAVPTVLGQGEYINLELRDTDFTTARRIVDTINSRFSYGTATALDGRVIQLRAPLNNNQRVTFISQIEDLDVIPAQGIAKVIINARTGSVVMNQMVTLESSAVAHGNLSVIINTQPIVSQPGPFAQRGETVVVPQSQIEVRSEEGNLMLLPGSASLADVVKALNAIGATPQDLLAILQALKASGSLRAELEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: FWDF_METJA
Sequence: MIEQIKEVYENGFTIYRDGEVEKRELCWNDELCVGCGICADICPVNAIAMGPLGAIAKGDIIAPKLDIDKDVCVLCGMCASACPFDALDLKINGKSIKEDERYPKIKRDIKVYQDKCVLCEQCEMVCPQGAIVVERELAEREKFVIGEININKEKCVLCGICAEYCPADAINLKYNYPTPSNPKPITDIEVDKDKCVFCKVCEFVCPHDAIEVICYKCPMMKRIPQAKLYEDITGKTVIDKDACVTCGWCAFICPAEAIEVEKPFKGELIIDVNACNACGACISICPCSALEFPKPKDKAEKVPRIIVNQNLCVLCGACAKACPVNAIKVKRTEINFEREPKAIAWKEAFKKLMG
What are the official names of this protein?
Polyferredoxin protein FwdF.
Protein: KCRB_RABIT
Sequence: MPFSNTHNTLKLRFPAEDEFPDLSAHNNHMAKVLTPEMDAELRAKSTPSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEAFKELFDPIIEDRHGGYKPSDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAVEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGQHEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.  Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation.  During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work.
What are the official names of this protein?
Creatine kinase B-type, B-CK, Creatine kinase B chain, Creatine phosphokinase M-type, CPK-B.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion. Note=Localizes to the mitochondria of thermogenic fat cells via the internal MTS-like signal (iMTS-L) region.
Protein: TBCA_YEAST
Sequence: MAPTQLDIKVKALKRLTKEEGYYQQELKDQEAHVAKLKEDKSVDPYDLKKQEEVLDDTKRLLPTLYEKIREFKEDLEQFLKTYQGTEDVSDARSAITSAQELLDSK
What is the function of this protein?
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
What are the official names of this protein?
Tubulin-specific chaperone A, Tubulin-folding cofactor A, CFA.
What is the protein family that this protein belongs to?
Belongs to the TBCA family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: QVR_DROAN
Sequence: MWTPRIAVNHWLLVTTAIFGFLTFIWIPQASAECQTRSIYCYECDSWTDARCKDPFNYTALPRDQPPLMTCNGCCVKMVRHQRSPYEVVRRMMCTSQLQINLFMVDHVCMMESSGNGHMCFCEEDMCNSSKDLHTNGCQLHLITIAVAMSWLMGQLLSR
What is the function of this protein?
Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation.  Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability (By similarity).
What are the official names of this protein?
Protein quiver, Protein sleepless.
What is the protein family that this protein belongs to?
Belongs to the quiver family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: GSC_PANPA
Sequence: MPASMFSIDNILAARPRCKDSVLPVAPSAAAPVVFPALHGDSLYGASGGASSDYGAFYPRPVAPGGAGLPAAVSGSRLGYNNYFYGQLHVQAAPVGPACCGAVPPLGAQQCSCVPTPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQLHCRRKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKRSSSEESENAEKWNKTSSSKASPEKREEEGKSDLDSDS
What is the function of this protein?
Regulates chordin (CHRD).  May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis.  In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity).  Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals (By similarity).
What are the official names of this protein?
Homeobox protein goosecoid.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOC_HERAR
Sequence: MKALLDLFKQVQQNEQFDAIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVTDPGMTPLKRCQIMSEDDYAAKYEEFGDDFTAFMGAEGIRELLRAIDIDRDAEMLRQELKDSKSEAKIKKYAKRLKVLEAFQRSGIKPDWMIMEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPEIITRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFIFNKLELMGLATTIKAAKKLVEIQEPVVWDILEDVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSIEAQMEARTLMLASNNILFPSNGEPSIVPSQDIVLGLYYATREAINAKGEGMMFPDVSEVIRAYDNKEVELATRITVRITEYPKNVETGEFEKTVTRYETTVGRAILSEILPKGLPFSVLNRALKKKEISRLINLSFRKCGLRATVVFADQLLQSGFRLATRAGISICVDDMLVPSQKVDIIATAEGEVKQIEQQYSSGLVTAGERYNKVVDIWGKAGDDVGKAMMDQLKVEDVTKRDGTKTTQESFNAIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVIEDDCGTSNGASMKALVEGGEVIEALRDRILGRVAANDIVNPETQATLYAAGTLLDEDMVEEIERLGIDEVKVRTPLTCDTRFGLCALCYGRDLGRGSMVNAGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGTVRFTATMRYVTNGKGGQIVISRSGEVLITDDLGRERERHKVPYGATLIVKDGLVIKAGTALATWDPLTRPIITEYTGTVKFENVEEGSTVARQIDEVTGLSTLVVIDAKRRGSVTKTVRPQVKLLNEQGEEVKIAGTEHAVTIGFQVGALITVKDGQQVTVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAGMLAEVTGTVAFGKETKGKQRLEITDMDGNKHEFLITKDKQVLVHDGQVVNKGEMIVDGPADPQDILRLLGIEALARYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQVVDAGDANYIVGEQVERSELLDENDRVIAQGKIPATYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDGLRGLKENVIVGRLIPAGTGLAFHRARKEKESWEAEERTALLQSEKAARAAEAEAQFADISSTPDSDTDAS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RAFP_PEDPE
Sequence: MQEEHNYKWVGGRLIYGFGAKGNDAFYSILSGYLIIFITSHLFDTGNKALDNRMVSLVTLIIMVLRIVELFIDPFIGNAIDRTKNSPGHFRPWVVVGGTVSSIILLLLFTNLGGLYAKNAMIYLVVFAILYITMDIFYSFKDVGFWSMLPSLTTDSREREKTATFARLGSTIGGGLVGVLVMPAVIFFSAKATSTGDNRGWFIFALIICLIALISAWGVGLGTREVDSDIRKNKQDTVGVMEIFKALAKNDQLLWAALAYLFYGVGINILGSLEVYYFTYIMGKPKSFSILSIINIFLGLIATSLFPVLSKKFSRKGVFAGCLVFMLGGIAIFTIAGSNLWLVLLAATMFGFPQQMVFLVVLMVITDSVEYGQLKLGHRDESLALSVRPLIDKFGGAISNGVVGQIAIISGMTTGATASSITAAGQLHFKLTMFAFPALMLLIAIGIFSKQIFLTEEKHAEIVAELERTWRTKFDNTTDQVAEKVVTSLDLATPIAGQVIPLAQVNDPTFAAGTLGDGFAIKPSDGRILAPFDATVRQVFTTRHAVGLVGDNGIVLLIHIGLGTVKLRGTGFISYVEEGQHVQQGDELLEFWDPTIKQAGLDDTVIMTVTNSTEFTMMDWLVKPGQAVKATDNILQLHTKA
What are the official names of this protein?
Raffinose carrier protein, Raffinose permease.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RXLRZ_PHYIT
Sequence: MRAVYILAMACAATLQASSSALPSTKDLNSQVESLVPSDITDSAHVGGVRLLRVEDKEEETEEERGFGGALADGLKKLNPAKAAKKAKEKAAKIKQDLKEIGEHAAWLEKMRETIGKD
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves.
What are the official names of this protein?
RxLR effector protein PITG_19617.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: LIPA_YERPS
Sequence: MSKPIQMERGVKYRDADKMALIPVKNVVTERQELLRKPEWLKIKLPTDSSRIQGIKAAMRKNGLHSVCEEASCPNLSECFNHGTATFMILGAICTRRCPFCDVAHGRPVTPDANEPEKLAQTIQDMGLRYVVITSVDRDDLRDGGAQHFADCISAIRAKNPTIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRVYRQVRPGANYDWSLKLLERFKEAHPDIPTKSGLMVGLGETNAEIVEVMHDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPAEFDEMKAEAMAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.