PharMolix/UniProtQA huggingface dataset:
Protein: SSRB_DICDI
Sequence: MNFKTVISLFLVLFVSFVYCENGAELLFHKKIVEGPVVGKELPIQFIIYNVGSEPAYDISFIDNDFSNAEFEFVSGSSEGKWETLAPNSQVQTNLTVIPKKSGIYSLTSTVLNYRKTQTSSEFTVSSAASYSGMYVESQADYEKRTSLLIKEWITFFVLCAGAIALPYSISTYYKKNYENGIKK
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Translocon-associated protein subunit beta, TRAP-beta, Signal sequence receptor subunit beta, SSR-beta.
What is the protein family that this protein belongs to?
Belongs to the TRAP-beta family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: URED_RHILW
Sequence: MMIAAAGTRPQRAEGRGHLAAKLLDGRTRLRELYQEGAAKIRLPDTFDASMEAVIINTAGGLTGGDRMDWSVEAGAGTRIDVTTQACEKIYKASAGTAEVRTSIKVGTQARVDWLPQETILFDRSALFRRLDVDLDESAEFLAVEAILLGRKAMGETVMTGLFRDRWRIRRSGRLIHAEELRLSEGVAALAARQAVLGGQVAFATLLYAGPLAEAYLGKVRPLVEGAMGGASAWDGKLVVRLAAADGFSLRKILIRVISALRNGAPVPKVWNL
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC27_DEBHA
Sequence: MSSLEPATTAKVALITTKGPIEIELWAKEVPNITRVFIQNCLDKKYIGTTFNKVIKDYLVQTSKIKEPATLKLKDEFHSRLKFNKRGLVGAVHDDKRNSNNVDSLFITLKPTPEFNNNYVLFGKIMGDSIYNVVKINESELKSEETPMYPAEITDIKILVQYFDDLVESKEHIAEPAKKKAKKAKKPRVKLDYTLEDEEDTGFKMKSAHDLLSDSKLSNKLYANKKKGPSENNEKQKTIEKAQDSSMETKKIVPERPDYKGSEEIENETKITSSENMNHETKQDKPNYKAKLDRNPNIDSDYDSDLDLSSSESIDLFAFKQSNFQSS
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Involved in pre-mRNA splicing (By similarity).
What are the official names of this protein?
Peptidyl-prolyl isomerase CWC27, PPIase CWC27, Rotamase CWC27.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MDTA_YERPY
Sequence: MKSQSKRTSRLFVFVGVVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTGLGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTGLISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVFTLPESDIPAIMQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIKVDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTTGIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPRSANTDTNPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARND_ECOL6
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQAHSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIEAKEAFHLRYNSDCRGAMPFRPLLESGTPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRIQRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSGTLPLGQVVRGNIAGREGWLGCQQIAGSH
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: UT019_PEA
Sequence: VLNQYLTELYYQVEANNKSYASNNELAVFPDQR
What are the official names of this protein?
Unknown protein from spot 19 of 2D-PAGE of thylakoid.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid.
Protein: EMBC_MYCLE
Sequence: MSGAGANYWIARLLAVIAGLLGALLAMATPFLPVNQNTAQLNWPQNSTFESVEAPLIGYVATGLNVTVPCAAAAGLTGPQSAGQTVLLSTVPKQAPKAVDRGLLIQRANDDLVLVVRNVPVVSAPMSQVLSPACQRLTFAAYFDKITAEFVGLTYGPNAEHPGVPLRGERSGYDFRPQIVGVFTDLSGPIPTGLNFSATIDTRYSSSPTLLKTIAMILGVVLTIVALVALHLLDTADGTQHRRLLPSRWWSIGCLDGLVITILAWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTPEAPFGWYYDLLALWAHVTTTSAWMRVPTLAMALTCWWLISREVIPRLGHAAKASRAAAWTAAGMFLAVWLPLDNGLRPEPIIALGILLTWCSVERAVATSRLLPVAVACIVGALTLFSGPTGIASIGALLVAVGPLLTILQRRSKQFGAVPLVAPILAASTVTAILIFRDQTFAGESQASLLKRAVGPSLKWFDEHIRYERLFMASPDGSVARRFAVLALLVALSVAVAMSLRKGRIPGLAAGPSRRIIGITVTSFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVASAALRSRRNRTVFAAVVLFVVALSFASVNGWWYVSNFGVPWSNSFPKLRWSLTTALLELTVIVLLLAAWFHFVATTNGSAKTRFGVRIDRIVQSPIAIATWSLVIFEVASLTMAMIGQYPAWTVGKSNLQALTGQTCGLAEEVLVEQDPNAGMLLPVSTPVADALGSSLAEAFTANGIPADVSADPVMEPPGDRSFVKENGMTTGGEAGNEGGTNATPGINGSRAQLPYNLDPARTPVLGSWQSGIQVVARLRSGWYRLPARDKAGPLLVVSAAGRFDHHEVKLQWATDSGAASGQPGGAFQFSDVGASPAWRNLRLPLSAIPSMATQIRLVADDEDLAPQHWIALTPPRIPQLRTLQDVVGYQDPVFLDWLVGLAFPCQRPFDHQYGVDETPKWRILPDRFGAEANSPVMDNNGGGPLGVTELLLKATTVASYLKDDWSRDWGALQRLTPYYPNAQPARLSLGTTTRSGLWNPAPLRH
What is the function of this protein?
Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
What are the official names of this protein?
Probable arabinosyltransferase C.
What is the protein family that this protein belongs to?
Belongs to the emb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CMOB_YERPP
Sequence: MIEFGDFYRLIAKGPLSPWLDTLPAQLSAWQRESLHGKFKTWFNAVEHLPQLTPTTLDLHSGVRAEMSPPISAGQREGMENMLRALMPWRKGPFSLYGLDIDTEWRSDWKWQRVLPHISPLAGRTILDVGCGSGYHLWRMIGEGAHLAVGIDPMQLFLCQFEAIRKLLGGDQRAHVLPLGIEQLPELAAFDTVFSMGVLYHRRSPLDHLYQLKNQLVTDGELVLETLVVEGDSQQVLVPGDRYAQMRNVYFIPSAPALKAWLEKCGFVDVRIADMAVTTTEEQRRTDWMTSESLAEFLDPHDHSKTVEGYPAPLRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: PURA_CRYNB
Sequence: MAPSPEGVTVVLGAQWGDEGKGKLVDILAAEADICARCAGGNNAGHTIVVRNDKGEKTSYAFNLLPSGLINPECTAFIGSGVVVHVPSLFNELDTLERKGLKVAGRLFVSDRAHLVMGFHQIVDGLKEVELGGSSIGTTRKGIGPAYSSKASRSGLRVHHLFDPTFPAKFRKLVEGRFKRYGHFEFDTEGEIEMYLAFAERLRPFIVDGPTFMHNAVNSGKRVLVEGANALMLDLDYGTYPFVTSSSTSIGGVVSGLGISPFAIKRVVGVIKAYTTRVGGGPFPTEDLATVGETLQEVGAEYGTVTGRRRRCGWLDLVVMKYSTMINGYTSLNLTKLDVLDGFDEIKVATGYKIDGVEVEGFPADLDRLAKVEVQYATLPGWKTDISNCKTYQEFPENAKAYIKFIEDYLGVKVQYVGVGPGRDQNVIIF
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC33_BOVIN
Sequence: MELLPLWLCLGFHFLTVEWRHRSGMVTAASQGGCELLDGVADCRGRNLASVPSDLPPSSRTLLLDANPLRTLGNNSLQRYPFLESLSLHDCYLERIGHVAFQEQARLRSLALPDNALSESYKETAAALHGLRGLRMLDLSGNSLTEDMAALMLQNLSSLESVSLARNIIMRLDESVFEGLGHLRELDLQRNYIFEIEGGAFDGLTQLRHLNLAYNNLPCLVDFSLTQLRSLNVSYNVLEWFLASGGEAAFELETLDLSHNQLLFFPLLPQCSKLHTLLLRDNNMGFYRDLYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFASSDLSSLRFLDMSQNQFQYLPDGFLKKMPSLSHLNLKQNCLVTLHIREHEPPGALVELDLSQNQLSELHLAPGLPGCLRSLQSFNLSSNQLLGVPAGLFANARNLATVDMSHNQISLCPLPASLDPGGTPGCVDFRNVASLQSLSLEDCGLEALQDCSFQGTALTHLDLSGNWGVLNGSIAPLWDVAPTLQVLSLRNVGLTSSFTELDFSAFENLRSLDLSGNALTSFPRFGGSLALQTLDLRRNLLTALPQRAVSEQLAGSLRTIYLSQNPYDCCGVEDWGALQRLHIVADLAMVTCNLSSKVIRLTELPAGVPQVCKWERVDMGLLYLVLILPSCLTLLVACTITFLTFRKPLLQVIKSRCHWSSIY
What is the function of this protein?
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system.  Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1.  TGF-beta-1 activation mediated by LRRC33/NRROS is highly localized: there is little spreading of TGF-beta-1 activated from one microglial cell to neighboring microglia, suggesting the existence of localized and selective activation of TGF-beta-1 by LRRC33/NRROS.  Indirectly plays a role in Toll-like receptor (TLR) signaling: ability to inhibit TLR-mediated NF-kappa-B activation and cytokine production is probably a consequence of its role in TGF-beta-1 signaling.
What are the official names of this protein?
Transforming growth factor beta activator LRRC33, Leucine-rich repeat-containing protein 33, Negative regulator of reactive oxygen species.
What is the protein family that this protein belongs to?
Belongs to the LRRC32/LRRC33 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: NNR_METHJ
Sequence: MTVIIQGRSFPDDLTQYAEFIGQGLLSPEEMRRIDQNAQALGISGLELMESAGTGLAMAARQYQPGKILILCGSGNNGGDGMVAARHLAGEADITVFWYDSGRQTDSTRTQLQRLLSCSVTSIPFRSRDDLIEHTRIFQDTDLIIDALLGTGGTGSVREPVRTCIEFANNAKAPILSADLPSPGIIPDRICAFHRAKTEGAHIYGIGIPLLAEISTGPGDLLILRNRNPDSHKGVGGNILVIGGGPYQGAPYLAGLAALRAGADIVRVVSPHYLPEPDIIHVPTAGDRITTADLATIIPLCKQADVVLCGPGLGPESHDVITSLAPYIRKGVFDADALRDPLPVAGESLYTPHAGEFARMSGLSPGKTPRERAHAIMKAQILGTVLLKGAVDVICDGSRVRFNQTGTPAMTTGGTGDVLAGVCAALMAVVPAFEAACIGAYVTGRAGELITQTCGYGMTARDLLTAVPQVLFRSTSERE
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: SYS_CHRVO
Sequence: MLDINLLRNDIEAVAARLAGRGYTLDTAAFNQLESERKSLQSRMQELQAKRNATSKQIGIAKGKGEDVSAILAEVATLGDELKAAEQAFDGVQGQLDAWLMSIPNLPHESVPVGKDENDNVEVRRVGVPRQFDFEVKDHVDVGAPLGLDFDTGAKLSGARFTVLKGDIARLHRAIAQFMLNTHTGSHGYQEHYTPYIVNDTALLGTGQLPKFADDMFKVTRGGDESAVPQYLISTSEVTLTNTVADTILQESELPKKMTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVRVEKPEHSYAALEEMVGHAENILKALELPYRVITLCTGDMGFGSAKTYDLEVWLPAQNTYREISSCSNCEAFQARRMKARYKDENGKNQLVHTLNGSGLAVGRTLVAILENYQNADGSVTVPTVLRPFMGKDRIGG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_GRAFK
Sequence: MKDTYRHQGKRQQLVKTVKKKGITDEKVLGAIGNIPRHLFMDSSFEDHAYQDKAFPIAADQTISQPYTVAFQSELLEIKKGEKVLEVGTGSGYQTAVLCLLGAKVYSIERQRELYKKTKSFLSKLGYRPKYLSFGDGYKGIPEYAPYDKIIVTAGAPEVPRDLLSQLKVGGRLVIPVGTDVQTMTLFIRKSAKEFDKNEFGAFRFVPLLEDKN
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_PECAS
Sequence: MFEINPVKNRIQDLAERSAVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAIVDTIDQLAQGLEDVTGLLELAVEEDDEDTFNETSAELDVLENKLGQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLVRMYLRWAEAKGFKTEIIEESDGDVAGTKSATIKIIGDYAFGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHLPTNIVTQCQNDRSQHKNKDQAMKQLKAKLYEFEMQKKNAEKQVMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGDLDKFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECA_CANGR
Sequence: ADTIVAVELDTYPNTDIGDPNYPHIGIDIKSIRSKKIAKWNMQDGKVATAHIIYNSVGKRLSAVVSYPNADSATVSYDVDLDNVLPEWVRVGLSATTGLYKETNTILSWSFTSKLKSNSTAETNALHFTFNQFTKDQKDLILQGDATTDSDGNLQLTRVSSDGTPQGNSVGRALFYAPVHIWESSAVVASFDATFTFLIKSPDSDPADGITFFISNMDSTIPSGSGGRLLGLFPDAN
What is the function of this protein?
Lectin (PubMed:24361256).  Induces paw edema in mice (PubMed:22368061).  Has a weak vasorelaxant effect on rat aorta (PubMed:24361256).  Has anti-inflammatory and anti-nociceptive effects (PubMed:19153712).
What are the official names of this protein?
Lectin ConGF.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: YTCI_BACSU
Sequence: MLKREDLIAPVQYNLVNEMEKFSAAGQKTALLWEDESGKQESWSYEKLMEETNKIGAALADLGFKKGDKLIVMVPRVLEAYAVYLAILKSGMVVIPCSEMLRAKDLEYRIEHAEVKGAIVYSEFIGAFRDVSTADKLITLSIGENDAGWKNLLSIEADGSQFKTADTTRDDMAFLSYTSGTTGQPKGVVHTHGWAFAHLKTSAGAWLDISEKDIVWATAAPGWQKWVWSPFLAVLGSGATGFVYHGRFKAEKYLELLNRYKINVFCCTPTEYRLMAKVEGLKRFDLSALHSAVSAGEPLNREVIDVFQKHFGIKVRDGYGQTESTLLVGVLKDTPIKPGSMGKPTPGNQVEIINEDGEICKPGEVGDIAVHLSTPALFKEYFKDPERMKTQIRGDYFLTGDRARKDEEGYFWFESRNDDIIISSGYTIGPFEVEDALVKHPEVKECAVVASPDEIRGSIVKAYVVLQNHEKRSDELVKMLQNHVKTITAPYKYPREIEFVESLPKTASAKIRRVELRKREEQLKANKKA
What are the official names of this protein?
Uncharacterized acyl--CoA ligase YtcI.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: MSHC_MYCLB
Sequence: MSAAVAPTCKATMYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHEVHYVQNVTDVDDPLFERADRNGVDWRDLAEREVALFRDDMASLRILPPHDYVAATETIVEIVELVDKMLVSGAAYVIDDEYPDIYFRADATLQFGYESGYDRDTMLRLYEQSGGDPRRPGKNGELDALLWRAARPGEPSWSSPFGPGRPGWHVECAAIALSRIGIGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDEHKMSKSRGNLVLVSTLRAQGAPPSAIRLGLLAGHYRADRFWSSQLLDDAIARLHRWRTAASMPAGPDVADVIARVRGYLADDLDTPKAIAALDGWVTDALEYGGHDAAAPKLLATAIDALLGVDL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: ENO_EHRCR
Sequence: MFNITISKILARQILDSRGYPTIEVETILSNDIKAKACVPSGASVGKFEAVELRDNDKNFYNGYGVTKAINLINSEVAPQIISMNTLNQEKIDNALIEIDGTDNKSRIGANSTLAISLAIAKAAALALNIPLYQYLGGITAKVLPTPLINVINGGMHADNNLDFQEFMIIPNGANKFEDAIRMSAEVFFQLKQILKHKKLNTNVGDEGGFAPNIRINTEVFEIIIDAVEKSGYKMYEDFSLGLDIAASTFYKDQKYKFADYELNTQELVEYYKKIISQYPIISIEDPIAEEDINGWKLITQELGNKIQIVGDDLFVTNCKLIQNGIDNNMANAVLIKPNQIGTLTETFNAIRLAQKNNYNVIISHRSGETEDTTISHIAVATNCGQIKTGSLSRSERLAKYNELLYIEKLLGISAIYYGSL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ALP14_SCHPO
Sequence: MSQDQEEDYSKLPLESRIVHKVWKVRLSAYEECSKSFSLSADGSDNCFELWNNQSELWKSVLTDSNVAAQEAGTAAFVAYCRFSDPSHLLKAREISVLSISEKCLTSPRAGTRENALEALMLLVEADSAAPVIESIIPSLSARSPKVIASNVAAIASLVEQFGAKVIPSKMIIPHISNLFGHADKNVRKEASRLTVNIYRWTGDPLKDLLFKDLRPVQTKELESLFAELPTEPPKQTRFLKSQQPTSEPNVETQVEEQPALENEESEPEPSDDQFDLVEEVDVLPNVDPNLETLMASSKWKDRKEALDKLLPVLSQPKIKDNDFFNLVAILTKSVSKDANIMVVINAAHCIQAMAKGLRSNFSKYASTSINALLERSKEKKANVIESLSSAMDAVLATSSLDDLAELIASFAGNKNPQIKSSCFSLFSRSFSNMTSLPSKFTVDTCAKACVPGVSDTFEPVRSAAAEALGVLMKLVGERAINQYLSPLDDIRKSKIRSFYETATVKAKAPTKKSKVKPSKQEESKVVVPSNAKAVKKSVVPSSPVVPSPRKATNKSLSMDVSKGNAFENGPLLPRPTTRPVSRGLSRGTSSSLQQKVKASTPLNSGALNETVQNLKNMELDDPAPQPAKHSRVDRYEHPKVLEDNDSTISSLESLKRENEELREQLKVEHEENISMQKQLSELKGELNTLRSARKASPIGDRKPAFMRRANTDFLELSTSPSFQRSVREFEPTRPKLYSSIDVNQRSPLASAKTNGNFTFHAELPRSPFSSRANNINPDWTKAIDLAAKLKQKITEMKQTDQRHQGLIH
What is the function of this protein?
Required for bipolar spindle formation and proper chromosome segregation.  Has a role in connecting the kinetochores and the plus end of pole to chromosome microtubules.  Also required for the activation of the spindle checkpoint pathway.
What are the official names of this protein?
Spindle pole body component alp14, Altered polarity protein 14.
What is the protein family that this protein belongs to?
Belongs to the TOG/XMAP215 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Chromosome, centromere, kinetochore. Note=Kinetochore periphery. Spindle localization is alp7-dependent.
Protein: HEM1_ALKOO
Sequence: MNIIMAGIDYKLAPIDVREGFSFTKAMMKQVYSNILKDTMIYGTVIISTCNRTEIYISCEEDFCVNPFEVLCNAAGIDFTPYEKVHRVKEGDEVIKHLCQLACGVKSQIWGEDQIITQVKNAIAVSREMRAADSYLEVMFRNAIAAAKKVKSTLILNSRENSIVHKALKIIKDQETMNIREILVIGNGEMGRLMTNVLIENGYRATMTLRQYRYHANVIPLNANTVDYSNRYEKMKDCDVVISATLSPHYTVEMENLKKIDKIPKLFIDLAVPRDIDPSIKNLPNIELYDVDGIGADEISKNHAQQLKGIERIIEKYICDYHKWCLFKEGLGCI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SYAC_DICDI
Sequence: MDVNQIRKTFIDFFREKCEHTFVPSSAVIPHDDPTLLFANAGMNQFKPIFLGQVNPKSEQAKLKRAVNSQKCIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGNYFKKEAITWAWELLTEVYKLDKERLYVTYFRGDPEKGLEADLEAKNLWLQYLPEERVLPFGMKENFWEMGDQGPCGPCSEIHYDKVEGRDGASFVNADDPTLIEIWNLVFIQYNREADKSLRPLPQKHVDTGMGLERLTSIIQKVPTNYDTDVFMPIFAAIQEVTGYPEPYGGKVGAEDTQQVDMAYRVIADHIRTLTFSIADGAAPSVDGRGQVLRRILRRAVRYGKQKLNAPAGFFSKLVDVVIANFGEFFPELRKKPEHIKMVLTREEDMFNKTLEKGIVEFEKMIKKSVNNTLSAENAYFLSTCYGFPIDLTTIMAEEKNYKVDIKGYEGLCEAQSEIDRKRQKEKKVELTLGAEANAWLKNNDIKPTDDSFKYKQHEIQSVIKAIWNGKEFVDTAPKGTLIGVVLENSNFYAEQGGQIYDIGQLSFIDDQKTAFDVKDCKVFGGYVLHIGYLSYECDSLKVGDRVELTVDYTRRSPIMSNHTSTHMVNYALKNILGDGIDQRGSFVDAQRFRFDFSFGRAITKDELIKIDQIVNDQIFKQLDVHAKEVGLASAKKINGLRAVFGEVYPDPVRVVSVGVPVEQLIENPTNPEWANYSIEFCGGTHLSNTKQAELFTITSEETLGAGVRRIVAVTGSEAASAIELNKELEVRFNNALKLSGSELAKEIVSLLDLLKVVTISASVRMNLVETLKEVQALQRKQVKEQETILAQQAQTYLEKTSEELAKSQPKVFVDLVNFNSNTPLITETIKKIQTKSPMTAIMLISPDEEKGKVTCIGIVPKDSEISKTLTANAWVVKVTEVLGGKGGGKVDVAQGVGSKLDKIDEAILVSREFANAN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, cytoplasmic, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCK1_RHYMA
Sequence: DPAFNSWG
What is the function of this protein?
This cephalomyotropic peptide stimulates contractile activity of cockroach protodeum (hindgut).
What are the official names of this protein?
Leucokinin-1, Leucokinin I, L-I.
What are the subcellular locations of this protein?
Secreted.
Protein: ALR_GEOSM
Sequence: MDSRPTVVEIDLAALRHNFSLVQKRVPEGCGLLAVVKADAYGHGFQYVSEELEKLGVDAFAVAFLAEGVQLRMSGITRPVLILGGIYPGEERRLIGLNISTALFSLEQAAALDQAALEIKCYRKAHIHLKVDTGMGRLGVPYHEVPEFLAKLKQFKNLELEGIFSHFASADELDPEGIAFTRLQAERFNAAVEEARRQGYAPSYVHVANSAAILAQDLPYCNLARPGIILYGALPSGDFEGQVPSQPVMRLKSRVAMLKWVEPGTSISYGRRYVATERALIASVPVGYADGYCRSLTNKGEALIRGQRAKVAGTVCMDWIMLDVTNVKGVAVGDDVTLLGPDPMGDCISAEEMAEKAGTIPYEVLCGIATRRVRRVYLG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: DHSO2_YEAST
Sequence: MSQNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYDYNIAHGGEVVKTIIFGPE
What is the function of this protein?
Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols.  Is active with D-sorbitol (D-glucitol) and xylitol as substrates, leading to the C2-oxidized product D-fructose and D-xylulose, respectively.
What are the official names of this protein?
Sorbitol dehydrogenase 2, SDH 2, Polyol dehydrogenase, Xylitol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: ESXB_MYCS2
Sequence: MAAMNTDAAVLAKEAANFERISGELKGVIAQVESTGSALAAQMVGQAGTAAQAALARFHEAAAKQVQELNEISANIHTSGTQYTSTDEDQAGTLASSMNI
What is the function of this protein?
An exported protein.  Plays a role in DNA conjugation, in at least a donor strain (PubMed:15314236).
What are the official names of this protein?
ESAT-6-like protein EsxB.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-1 / type VII secretion system (T7SS). Accumulates in the cell and is secreted when grown in Saunton's medium, when grown in 7H9 medium protein only accumulates intracellularly (PubMed:15687187).
Protein: CALM_HETTR
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDSDGNGTIDFPEFLSLMARKMKDTDTEEELIEAFKVFDRDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKMMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.