PharMolix/UniProtQA huggingface dataset:
Protein: H2BS2_PARAN
Sequence: MPRSPAKTSPRKGSPRKGSPSRKASPKRGGKGAKRAGKGGRRRRVVKRRRRRRESYGIYIYKVLKQVHPDTGISSRAMSVMNSFVNDVFERIAGEASRLTSANRRSTVSSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTTSR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.2, sperm.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: APOE_CANLF
Sequence: MKVLWAALVVTLLAGCWADVQPEPELERELEPKVQQELEPEAGWQTGQPWEAALARFWDYLRWVQTLSDQVQEGVLNTQVTQELTALMDETMKEVKAYKAELDEQLGPMTSETQARVAKELQAAQARLRSDMEDVRNRLTQYRGELQAMLGQSSEELRARFASHMRKLRKRVLRDAEDLQRRLAVYKAGVREGAERSVSSIRERLWPLLEQARERNAKVGALATQPLLERADALGQQLRGQLEEMSSRARGHLEEMREQIQEVRVKMEEQADQIRQKAEAFQARLKSWFEPLLEDMQRQWDGLVEKVQAAVATIPTSKPVEEP
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: PYTC_ASPTN
Sequence: MTVLTAAEPPNRIEVDMDAPSLDTDSSCTSLSSSVQRYEYKHGRRYHGYHAGSYPFPNDKREQDRLDMIHHVYTRILNDRLFLAPLDPRGKAILDIGTGTGIWALHMGDAHPAARLIVGNDLSPIQPSWAPANVRFVVDDVEKDWVDRHPYDFIHCRYMAGSIKDWPRLIRQCYAHLRPGGWLELQESVNVMYSEDGTLPPDSFMARMMHGLIVACEKSGRTMDPAPSMEKWVQEAGFDPITKHRFKIPVGSWPKDPRLKECGSLMRVNFVEGVEAFTASLFTEVLGWTPEEVAVLNTGVREEAMRNDIHAIFDFVVIVAQKPY
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of pyranterreones, a family of antioxidative compounds (PubMed:32077283).  The first step of pyranonigrins biosynthesis is performed by the hybrid PKS-NRPS synthetase pytA that condenses 4 malonyl-CoA units ato the acetyl starter unit by the modular PKS of pytA (PubMed:32077283).  The acyl chain is then connected to an L-serine through the amide bond by the modular NRPS of pytA (PubMed:32077283).  A tetramic acid is formed and released from the PKS-NRPS pytA to give pyranterreone 5 with the help of the thioesterase pytI (PubMed:32077283).  Pyranterreone 5 could be methylated by pytC to afford pyranterreone 6 (Probable).  Both pyranterreones 5 and 6 are subsequently oxidized by the FAD-linked oxidoreductase pytB and the cytochrome P450 monooxygenase pytD to form the fused gamma-pyrone core, resulting in pyranterreones 7 and 11, respectively (PubMed:32077283).  The hydroxy group at C-8 of pyranterreones 7 and 11 are dehydrated by the aspartyl protease pytH to form a delta-7 double bond to give pyranterreones 3 and 1, 2 accordingly (PubMed:32077283).  The exo-methylene of pyranterreone 3 could be reduced into a pendant methyl by reductase pytE to provide pyranterreone 4, also known as cordylactam (Probable).  Pyranterreone 4 can be reconverted to pyranterreone 3 through pytB-catalyzed dehydrogenation or further oxidized to pyranterreones 9 and 10 (Probable).
What are the official names of this protein?
Methyltransferase pytC, Pyranterreones biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
Protein: NNJA3_ORYSJ
Sequence: MASRDFLGVFGGGGGERRAANGSGSAVGGESDEIELSLGLSLGGRFGTDMSPDAKRARLARSSSIASVCSVSAADGDPSPAAPLPLLRTSSLPTETEEERWRRREMQNRRRLEARRKRLERRISVGSSSVPNKPGREDGGDGAVNRLQLRRSIGSQGSSSANPQDQGPDGSAICQSTEARSPSTSDDTNQNSALPPTASTGKPLNGTVTQQSPLRTLGSLTMRTSSTGDIGKIMMDMPMVSSKVEGPNGRKIDGFLYKYRKGEDVSIMCVCHGKFHSPAEFVKHAGGGDVSNPLRHIVVNPSPSVFL
What are the official names of this protein?
Ninja-family protein Os03g0419100.
What is the protein family that this protein belongs to?
Belongs to the Ninja family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSPE_BACCR
Sequence: MTLTGKVKWFNSEKGFGFIEVADGNDVFVHFSAITGDGFKSLDEGQEVSFEVEEGNRGPQAKNVVKL
What is the function of this protein?
Can bind to ATTGG and CCAAT motifs (Y-box motifs) of single-stranded oligonucleotides.
What are the official names of this protein?
Cold shock-like protein CspE.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMR6_ARATH
Sequence: MNGSWITILSLLVISQLASSKVTLIGKNTFLSFDDVEANFTPVVRRSGEYGLLYAAEPLDACSYLTNMAEKGSKFRPSYVLIVRGGCSFEEKIRNAQEAGYKAAIVYNDRYEELLVRMAGNSSGVYIHGVLVTRTSGEVLKEYTSRAEMELLLIPGFGISSWSIMAITFVSLLVISAVLASYFSVRRHRIRQHVRDLHHGGQGHSRMPKDLLQSMPTEVYTGVLEEGSTSVTCAICIDDYRVGEILRILPCKHKYHAVCIDSWLGRCRSFCPVCKQNPRTGNDVPPASETTPLISPGPNSITSLQSFYDLPIVVRVYL
What is the function of this protein?
Involved in the trafficking of vacuolar proteins.  May function as a sorting receptor for protein trafficking to the protein storage vacuole (PSV) (By similarity).
What are the official names of this protein?
Receptor homology region, transmembrane domain- and RING domain-containing protein 6, AtRMR6.
What are the subcellular locations of this protein?
Prevacuolar compartment membrane. Protein storage vacuole membrane; Single-pass type I membrane protein.
Protein: GMHA_GEOMG
Sequence: MNEEIMTQLRSHREVMEAVERELTPRIAAFAGMLVAALKGGKKLLVMGNGGSAADAQHFAAEIVGRFKMERRGLPAVALTTDTSILTAIGNDYGFDAVFRRQVEALADEGDVVVGLSTSGSSRNVYDALALANDRGCITVGLLGRDGGTLKDIVDLDVTVPSGDTPRIQEGHITIIHIVCDLVEKGLFK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_PSEP1
Sequence: MNRVLYPGTFDPITKGHGDLVERASRLFDHVIIAVAASPKKNPLFPLEQRVELAREVTKHLPNVEVIGFSSLLAHFAKEQGANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSERYSFISSTLVREIAALGGDISKFVHPVVADALTERFKK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOTX_DROSI
Sequence: MGLHIGSLLICVFLGILPFATANTNRSGYEEQRNYLLNIFHNPLVNDSIKEKNIPELIAFYQRYPTDVPLSDADRQQFERFIHDYREYREVLVDGVPPQGGSFGNIFGHFLGRVGTRYISSLFNKKREEGQSNHANSPTTLPSRIQKMTK
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot X.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPRT_PSEFS
Sequence: MPEQLNTRVEDCFLQAESFFKRSFKRPQVSLKLRGQKAGVAHLHENLLRFNPQLYRENSQHFLKQTVAHEVAHLIAHQLFGERIQPHGEEWQLIMRGVYELPPDRCHTYEVKRRQVTRYIYRCPCADSDFPFSSQRHGMVAQGRRYLCRRCRQTLVFTGETRVE
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2_PIPCE
Sequence: MAINLYKTSIPSTRKGAVDSQVKSNPRNNLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNDKDISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPISMGNALPLTDMPLGTAIHNIEITLEKGGQLARAAGAVSKLIAKEGKSATLRLPSGEVRLISKNCSATVGQVGNVEVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPATPWGYPALGRRSRKRNKYSDRFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYB6_PROM2
Sequence: MANSSSVYDWFQERLEIQDITDDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVTQAYSSVSYLMTDVSFGWLIRSVHRWSASMMVLMLILHVFRVYLTGGFKRPRELTWVTGVVMAVITVAFGVTGYSLPWDQVGYWAVKIVSGVPAAIPIIGDFMVELLRGGESVGQSTLTRFYSLHTFVLPWSLAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: Y3031_BORPA
Sequence: MRRPVPYHRVAAIMTILSLAGAGHQARLDARGGMLTGPTANLAPGHVQANLAILPQAVAGDFLRFCQRNPKPCPLLAVSEPGDPSLPELGLDIDIRTDVPRYRVWRDGKLVDEPLDVRGLWRDDLVAFLIGCSFSFEEAMLENGLPVRHIEQGCNVPMYRTNIATHPAGPFSGPLVVSMRPLKAADAIRAIQVTSRFPSVHGAPVHLGDPALIGIADLGRPDYGDAVEIRAGEIPVFWACGVTPQSVVAAVRPEFCITHAPGHMLVTDLLNSRLAAF
What are the official names of this protein?
Putative hydro-lyase BPP3031.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: YCX1_GUITH
Sequence: MRHLFKLLFLYMQLNLLFYIPNKKSFLQLGEEKVYLTFQNSNTNLNIPYDSLLHKLNSDKNVFSKESYDNWSSFRQLIIDKYGRIQGILTESSKNSNLKNSIQLNNYLLQKTIYYEFLCIEFQLY
What are the official names of this protein?
Uncharacterized 15.1 kDa protein, ORF125.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BR1CD_RANDY
Sequence: MFTLKKSLLILFFLGTINFSLCEEERNAEEERRDDPEERDVEVEKRFLPLLLAGLPKLLCFLFKKC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Brevinin-1CDYd.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: PSBK_STAPU
Sequence: MFNAYLDTVLDLSANGTVILAKLPEAYAIFDPIVDVMPIIPVFFLLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NTRYL_RICCN
Sequence: MLSYLKQNLHSYFSSRVLIFTLATAAIIFACATFYVISLESKNFSTIIGFLLVDLAIFLILGVVLTQKFFTKNNNNDSSKLQNRIVIAFSLVAAIPTIIVSVFSVYFFNLSVQAWFDKKISTVLDQSVIVAESYIAEHKLQLKETALAVAEDLSDMYYDLIHNPALFTKTLNTEAEMRSLDEAIVLNKSTNTIVANSYLSFSLSFATIPAHLIKKADLGELVEVKSDPTKIRMLIKLKEYNDVYLLVGRLVDNKIIDHVDATNGAAAEYNSLKNEIDNIQIKFSIMFIFIALLLLFVAISFGVIFTAKIVKPIKKLVTATDNVKDGDLTVQVPENEVDKDEIGTLYVAFNRMIKQLSRQQRDLVIAQRAMAWSDVAKKVAHEIKNPLTPILLASERLLKKFSPEIKERVEFENYLKMIIRHTNDIKNIVSEFVLFARLPAPKFTKSELVYLVKHIVEARKLLNDHILYKFESNVEQFDFMCDATQINQVMINLLKNAEESIEGRESGKIEVTIDVKDDFISVIVTDNGKGFPPELIGKATESYVTTSSKGMGVGLAIVKRIVEEHCGILDIANREAEGAIIDIKFDLKELDLKAKRLEM
What is the function of this protein?
Member of the two-component regulatory system RC0948/RC0849.
What are the official names of this protein?
Putative sensor histidine kinase NtrY-like.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGD_METTH
Sequence: MDSEEIIELERKFIMQTYTRQPIVLSHGKGATVWDIEGNSYIDCFAGVAVNSIGHAHPKVALAICHQAQRLIHSSNIYYTREQVELAKLLTAISPHDRVFFANSGAEANEGAIKLARKFTGKSEIIAAENSFHGRTLATVTATGQKKYSEPFRPLPEGFKHVPYGDIGAMADAVGDETAAIILEPVQGEGGVIIPPEGYLKDVQELARQNDVLLILDEVQTGFGRTGAMFASQLFGVEPDITTVAKAMGGGYPIGAVLANERVAMAFEPGDHGSTFGGNPWGCAAAIATIEVLMDEKLPERAAKMGSYFLGRLRQVLHGCDAVRDIRGVGLMIGIEIDGECAGVVDAAREMGVLINCTAGKVIRIVPPLVIKKEEIDAAVDVLGHVISDL
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YICS_SHIBS
Sequence: MKPTTLLLIFTFFAMPGIVYAESPFSSLQSAKEKTTVLQDLRKICTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERNNQSNYWEALGKVECPDM
What are the official names of this protein?
Uncharacterized protein YicS.
Protein: NADK_GEOMG
Sequence: MKKIAIFAKVHDPRCQGVAGELITWLEQRRIVPLVEAHFARHLGRSGVTSEEIPDLADMAVVLGGDGTLISAARLLGGREIPILGVNLGSLGFLTEVTLDELYPALEACLGGDYRVSERMMLAATVERGDDIVFSHRVLNDAVINKGALARIVDMESLVNGHYLTTYKADGLIISTPTGSTGYCLSANGPIVHPDLECLTITPICPHTLTNRPIVLEASAEVTIRLISKNEDVYLTLDGQVGMELKCGDIIRVRRAEHRTRLVMSRSKDYFEVLRTKLKWGER
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_SALPC
Sequence: MSVSAFNRRWAAVILEALTRHGVRHVCIAPGSRSTPLTLAAAENPAFIHHTHFDERGLGHLALGLAKVSQQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQAGMFASHPSQTLSLPRPTQDIPARWLVSTIDNALAMLHAGALHINCPFAEPLYGDMNDTGLVWQQRLGDWWQDEKPWLREARRLESDKQRDWFFWRQKRGVVVAGRMSAEEGKKVAQWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKAVTELQQAQIVVQLGSSLTGKRLLQWQATCEPEEYWVIDNIEGRLDPAHHRGRRLVAKIADWLELHPAEKRKPWCVEIPRLVELAWQRVVAQRDTFGEAQLAHRIRDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASAKSTLAIVGDLSALYDLNALALLRQVSAPFVLIVVNNNGGQIFSLLPTPQSKRERFYLMPQNVHFDHAAAMFNLRYHRPENWEELESALAGAWRTPAATVIELVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RRF_PSEA6
Sequence: MIDEINVDARQRMEKSVLALRGQFTKIRTGRAHPSLLDSIMVPYYGAPTPLKQLANVIAEDSRTLALTVFDKSAAQAVEKAIMQSDLGLNPMSAGTVIRIPMPALTEERRKDLIRVVRNEAEGGRVAVRNIRRDANGDIKELLKEKEISEDDAHRGEDAIQKLTDEFVKQIDDILAAKETELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOE_BACCQ
Sequence: MDFKQYSPEELKECSMIEVVHSVLGDKKQATTFNELVQEIAQVLGLSQEQVNAKIAQFYTDLNIDGRFINLGENRWGLRSWYPYEQIDEEILPQPKPKKKRKVEEDGFDDYIEEDEDDFDDVDGNEDEDDDVEDLDKVLEDEDGDDDDLDDLDDDEDDFAEEELEYDETEEEEEEEL
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: PBPB_MYCS2
Sequence: MSRRGDRPRTPAQPRKKARVDQPRSARTRRTRVSEAEAGLRSSSFVFRHRTGNLAILAVLVIAAVQLFMLQVPRAAGLRAEAASQLKVTDITPAIRGSIIDRNNDKLAFTIEARALTFQPTRVRKQLDEAWRKAQEAGSSTSDDVPNPDERLNEIAKEIAARLNNTPDAKTVLKKLKSNETFVYLARAVDPAIANAITDKFPEVGSERQDLRQYPGGSLAANIVGGIDWDGHGLLGLEDSLDAVLAGTDGSVTYDRGSDGVVIPGSYRNRHDAVDGSTVQLTIDDDIQYHVQQQVQMAKDASGAKNVSAVVLDAKTGEVLAMSNDNTFDPSQDIGRQADRQMGNPSVSSPFEPGSVNKIVTAAAAIENGLTNPDEVLQVPGSIHMGGVTVRDAWNHGVMPYTTTGVFGKSSNVGTLMLAQRVGPERFYEMLRKFGLGQRTNVGLPGESSGLLPPIDQWSGSSFSNLPIGQGLSMTLLQMAAMYQTVANDGVRVPPRIIKSTIAPDGTVTEEERPEGIRVISPETARTLRSMFRSVVQRDPMGVQQGTGPQAAVEGYQIAGKTGTAQQINPACGCYYDDVYWITFAGIAPADDPRYVIGIMMDAPQRAADGSPGSSAAPLFHEIASWLLQRHNVPLSPDPGPPLTLQAT
What are the official names of this protein?
Penicillin-binding protein PbpB, PBP3.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ISCS_PSE14
Sequence: MKLPIYLDYSATTPVDPRVAQKMIDCLTVEGNFGNPASRSHVFGWKAEEAVENARRQVADLVNADPREIVWTSGATESNNLAIKGVAHFYASKGKHLITSKVEHKAVLDTTRQLEREGFEVTYIEPGEDGLITPAMIEAALRDDTILVSIMHVNNEIGTINDIAAIGELTRSRGVLFHVDGAQSTGKVEIDLASLKVDLMSFSAHKTYGPKGIGALYVSRKPRVRLEATMHGGGHERGMRSGTLATHQIVGMGEAFRIAKEEMAAENVRIKALSDRFFKQVENLEELYVNGSLTARVPHNLNLSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFTFGRFSTEEEIDYAAQKVCEAVTRLRTLSPLWDMFKDGVDISKIEWAAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSJ_ECOLI
Sequence: MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGMRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKDGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: HYALP_RAT
Sequence: MGELQFKWLFWRSFAESGGTFQTVLIFLFIPYSLTVDYRATPVLSDTTFVWVWNVPTEACVENVTEPIDLSFFSLIGSPRKTAIGQPVTLFYVDRLGNYPHIDAQQTEHHGGIPQKGDLTTHLVKAKEDVERYIPTDKLGLAIIDWEEWRPTWMRNWTPKDIYRNKSIELVQAADPAINITEATVRAKAQFEGAAKEFMEGTLKLGKHIRPKHLWGFYLFPDCYNNKFQVDNYDGQCPDVEKKRNDDLDWLWKESTGLYPSVYLKKDLKSSRKATLYVRYRVLESIRVSKVSDESNPVPIFVYIRLVFTDHVSEYLLEDDLVNTIGEIVAQGTSGIIIWDAMSLAQRSAGCPILRQYMKTTLNPYIVNVTLAAKMCSQTLCKEKGMCSRKTESSDAYLHLDPSSFSINVTEAGKYEVLGKPEVKDLEYFSEHFKCSCFSKMTCEETSDMRSIQDVNVCMGDNVCIKATLGPNSAFHLLPGKGLLLMTTLAHILHHLPHDIFVFPWKMLVSTP
What is the function of this protein?
Involved in sperm-egg adhesion.  Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida.  The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation.  This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid (By similarity).
What are the official names of this protein?
Hyaluronidase PH-20, Hyal-PH20, Hyaluronoglucosaminidase PH-20, Sperm adhesion molecule 1, Sperm surface antigen 2B1, Sperm surface protein PH-20.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: CBIT_SALTI
Sequence: MKDELFLRGENVPMTKEAVRALALSKLELHRASHLIDVGAGTGSVSIEAALQFPSLQVTAIERNPAALRLLDENRQRFACGNIDILPGEAPMTITGKADAVFMGGSGGHLTALIDWAMGHLHPGGRLVMTFILQENLHSALAHLVHIGACRMDCVQLQLSSLTPLGAGHYFKPNNPVFVIACQKEENHVRDI
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Bacterial-type CbiT family.
Protein: PPAC_STAS1
Sequence: MAKTYIFGHKNPDTDAISSAIIMADFEQQTGNAEATAYRLGEVGPETQYALDHFNVTAPELLNDDLADQNVILVDHNEFQQSADSIADAAVQHVVDHHRIANFETAAPLYYRAEPVGCTATILYKMYKERGFEIKPEIAGLMISAIISDSLLFKSPTCTEQDVQAAEALKSIANVDLESYGLEMLKAGASTKDKSVSDILSMDAKSFNMGDFVTRIGQVNTVDIDEVFARQEELEKEMLEVSANEKYDLFVLVVTDIINSDSKILVVGAEKDKVGVAFNVTLDNNTAFLPGVVSRKKQVVPQITEALTK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.