PharMolix/UniProtQA huggingface dataset:
Protein: EPG6_CAEEL
Sequence: MSKKEETIFFRIEKENRPESSKKEEDENSTEEMTTLNHASVTLDHSAFAIADKDGFKMYQLNPLHFRMYKDYVIKVGPVRLVKQDGNSRRIIYVSALAGGRFAQNNLMIFDVARNEEYFEITTPSRYGPITNIHVSPNRLVALNPNRMFVWTYPDDIKQIRSEDIRSNPKGISAMSYDPTTAACYLAYPGFKTGSVQIMHLNALTARESKSPIVIEAHLTDIAQVALNCQGTLVATGSTKGTVIRVFDARTKGPLYELRRGTVQAHLQCMAFSPCSSYLAVASDKGTLHMFGIRDAEPQKKKNVLERSRGSSSIVKIQLDRPVMAIGFGKIPETPKNLQSIIAICADATYWRHEFYKDNTGNFTSHFGSYDELIEVANDSSFFRTPVE
What is the function of this protein?
Component of the epg-6/atg-2 complex, which is involved in the generation of autophagosomes from omegasomes and in the distribution of atg-9 and atg-13 during the autophagy-mediated degradation of protein aggregates (PubMed:21802374).  Binds to phosphatidylinositols on preautophagosomes, which are early autophagic structures, to promote autophagosome formation (PubMed:21802374).  In particular, binds with high affinity to phosphatidylinositols including phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P), but more weakly to phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:21802374).  Involved in autophagy-mediated degradation of ribosomal RNA and ribosomal proteins in lysosomes, which is essential for maintaining nucleotide homeostasis (PubMed:30102152).
What are the official names of this protein?
Ectopic P granules protein 6.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=Localizes to the cytoplasm of all cells during embryogenesis.
Protein: HBB_GYPRU
Sequence: VHWTAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTQRFFASFGNLSSPTAIIGNPMVRAHGKKVLTSFGEAVKNLDNIKNTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFGKDFSPDCQAAWQKLVRAVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DRA2A_DEIRA
Sequence: MTYVILPLEMKKGRGYVYQLEYHLIWCVKYRHQVLVGEVADGLKDILRDIAAQNGLEVITMEVMPDHVHLLLSATPQQAIPDFVKALKGASARRMFVAYPQLKEKLWGGNLWNPSYCILTVSENTRAQIQKYIESQHDKE
What is the function of this protein?
A transposase that is part of insertion sequence (IS) element ISDra2, it is necessary and sufficient for both transposon excision and insertion of ISDra2.  This protein alone can be provided in trans and allows transposition of an empty IS element (tnpA or tnpA-tnpB replaced by a selectable marker) (PubMed:16359337, PubMed:20090938).  ISDra2 binds subterminal imperfect palindromes at the left (LE) and right (RE) ends of the element and cleaves only the 'top strand' which is circularized and subsequently reinserted into the DNA target.  This is called a 'peel and paste' mechanism and increases the copy number of the IS (Probable) (PubMed:20890269).  Transposition is linked to DNA replication in the absence of irradiation, with maximal activity when the 'top strand' is on the replication lagging strand, and occurs preferentially on the lagging strand (PubMed:20691900).  The IS element inserts 3' of the target sequence 5'-TTGAT-3'; target duplication has not been observed (PubMed:14676423, PubMed:16359337, PubMed:20090938, PubMed:20691900).
What are the official names of this protein?
ISDra2 transposase TnpA, TnpA-Dra2, Transposase for insertion sequence element IS200/IS605.
What is the protein family that this protein belongs to?
Belongs to the transposase 17 family.
Protein: PSBA_CHAGL
Sequence: MTATLERRESASLWGRFCDWVTSTENRLYIGWFGVVMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIVPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFFLGICCYMGREWELSYRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLASVEAPSVNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PUR8_DEIRA
Sequence: MIDRYLTPEMKVLWSEANKYRAWLKVELSALQAQARHGEVPAEAHAALVQKSEADPLDDAFAQQVAEIEAVTRHDIVAFTRALTERYGEEARFIHHGLTSTDVVDTAQNLLLDEAMGLIITDVQTLREVCRMQAAAHKHTPVVGRTHGIHAEPMTFGLKFLNWMATLDRDLERLQAARGRVQVVMLSGSVGTYAHVSPKIEEEVAESWGWHAAPVTNQTLARDRHAEVLAALAILGTTLEKIAVEIRHLQRSEVREAMEPFGKGQTGSSSMPHKKNPILTENVTGFARLLRGFLATGLENVALWHERDISHSSAERVILPDATASASYATRRLTGVLRDLVVFPERMLKNLDDLGGLVFSQRVLHALIDDKGMMREAAYGIVQRNALKSWETGEGLRDLLKADPENPLSDAELDAAFDLQWYLRHVDDIYARFGM
What is the function of this protein?
Catalyzes two reactions in de novo purine nucleotide biosynthesis.  Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
What are the official names of this protein?
Adenylosuccinate lyase, ASL, Adenylosuccinase, ASase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: SYS_PSEP1
Sequence: MLDSKLLRGQLQEVADRLASRGFSLDVARIESLEERRKAVQTRTEQLQAERNARSKSIGQAKAKGEDIAPLMADVERMANELAAGKAELDAIQAELDSILLTIPNLPDASVPVGASEDDNVEVRRWGTPKAFDFEIKDHVALGEISRGLDFEAAAKLSGARFAVLRGPVARLHRALAQFMINLHTGEHGYEEHYTPYMVQAPALQGTGQLPKFEEDLFKITREGEADFYLIPTAEVSLTNLVAGEILDAKQLPLKLVAHTPCFRSEAGASGRDTRGMIRQHQFDKVEMVQVVEPSKSMEALEGLTANAERVLQLLELPYRVLALCTGDMGFGAVKTYDLEVWVPSQDKYREISSCSNCGDFQARRMQARWRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSILVPEVLKPYMGGVEVIR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_METMA
Sequence: MEIRMSKSSSKPVLVTCGLPYANGKAHIGHLRTYVPADIYARSLKKEGREVTFVCGSDTHGTPIVVNAEELGITPTELVEIYHKHFDETFKQLGIYFDAFGTTDDPENHNRTHDIVSRLIEKGYVYPKIIEIAYCPACNRFLPDRYVEGACPHCGETARGDECDQGCGKHLEPGELQNPVCTICGGPAEYRQQEHFFFKLSEFSNYLMDYLSKDLGGTTNAINYARGWVKQGLTDWCITRNLEWGVKFPGHEDLVVYVWVDAPIGYIAFTEEWAAQAGDSWEKFWKGDGEIVHFIGGDITYHHCIFWPAMLKGADYSVPTAVVASGMVKIEDRKFSKTRGYVVWVGEDYLDHGFHPDLLRYYLASYTSHTKELNFSWRVLQEKINAELVAVLGNFLYRTMLFAFKNYGEVPEGEVEPEIRKEIEKALVEVKAAMEEYEFKKAVDSAMALASFGNTYFQSHEPWKLIKEDRDACGQVVYNCLHLAKALSLIFEPVIPQTMEKAWKGLGHESDIHAALYEETLVPLKAGTKLAKPEILFTKLEDDRIGEMEEIANQRVAAANAKRNGVKGGEKEPSKSEGMGPSEASKASEKTVDVATAEEKVQVETLPVIDYEDFAKLDIRVGKVLLVEPVKKSKKLLRIEVDIGEEKPRQLVAGMASYYTPEELVGKSVIVLANLKPAKLCGVESNGMMLAADDGGAIVAALMPDKEIKSGSRIR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDZ_SALSV
Sequence: MKKSLTNLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNTPLGLAPTPLMVSMEQSLADWMQMGNQLLDKPHHQTPRGLKFELAAESPLMMIMFNSLSQQIYQRYPQATIKVRNWDYDSLEAITRGEVDIGFTGRESHPRSRELLSLLPLAIDFEVLFSDLPWVWLREDHPALREAWDLDTFLRYPHISICWEQSDTWALDDVLQEMGRKRHIALSLPGFEQSLFMAAQPDHTLIATAPRYCQHYNQLHQLPLVARPLPFDAQQREKLMVPFTLLWHKRNSHNPKIVWLRQAINTLCRRLI
What is the function of this protein?
Involved in anaerobic NO protection.
What are the official names of this protein?
HTH-type transcriptional regulator YidZ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: SYH_ECOL6
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_ECO27
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL28_BURTA
Sequence: MARVCQVTGKAPMSGNNVSHANNKTKRRFLPNLQNRRFWVESENRWVRLRVSNAGLRLIDKNGIDSVLADLRARGEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: KPRB_HUMAN
Sequence: MFCVTPPELETKMNITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD
What is the function of this protein?
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.
What are the official names of this protein?
Phosphoribosyl pyrophosphate synthase-associated protein 2, PRPP synthase-associated protein 2, 41 kDa phosphoribosypyrophosphate synthetase-associated protein, PAP41.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: RL9_CROS5
Sequence: MAKRVQVVLNESINKLGKDGDLVEVAPGYARNYLLPQKLATLATPGILKQVEQRREKERQRLLAEKQQAEGQKTALETIKRFTIRKEVGEGEAIFGTVTTSEVAEAIQAATNQEVDRKGITVPDINKTGFYEATVKLHPEVTATIEIQVAPL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: MTNA_XANCP
Sequence: MNDSAHIDYARYDHIRPLLWTGDALELLDQRKLPFVVEHVRCDSSDAVAEAIHSLAVRGAPAIGIAAGWGVVLAAREIAADSGSEALQKLEPALLRLNAARPTAVNLAWALMRMRRVLAAAGPDWRDVLAREAQAIADEDLAANRHMGALGAGLIAPGSGVLTHCNTGSLATAGFGTALGVIRAGMAQQRISKVFAGETRPWLQGARLTVWELQQDGIDATLIADSAASHLMKSGLVQWVIVGADRICANGDTANKIGSYQLAIAARHHGVKFMVVAPSSTVDMATADGDQIEIEQRDPGELFGVGGVRTVADGIHAWNPVFDVTPGHLIDAIVTERGVIAQPDLARMQAAFGN
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: FIBS_EUPSU
Sequence: IVGGNEVTPHAYPWQVGLFIDDMYFCGGSISVTLTGWGKP
What is the function of this protein?
Serine protease with fibrinolytic activity.
What are the official names of this protein?
Fibrinolytic protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: DAPF_LISW6
Sequence: MAIIHFTKVHGSQNDFFLVDEEENHITAWSDTKRADFAIKLCDRSHSLGGADGILYVAKSNKAGAIGQMRVVNSDGSIASMCGNGLRTVARYLLEKHALTDAKVETMKAILDVRKATSLGFDIPTYQVEISPVKFNPESLPMYVGVEKLFNQVIPELDEELAFSAVSVPNPHLITFVDQTVLDSDKQEKLASFLNSENPYFPDGVNVSFVKRLNEDAIYVRTFERGVGFTNACGTAMSACSLIKKMLDQDTLETPLNVYNDGGRVQVTAKKDETGDISLQLIGNATFVSTGSVRYDDIVTELTNEATVEQAQYQELVQEVKHFLKTTG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_XANCP
Sequence: MFSRDVRLETYDPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGGCEFVDIAEQLAIDRIKQVFGADYANVQPHSGSQANQAVYLALLQPGDTILGMSLAHGGHLTHGAKVNASGKLFNAVQYGVNEQGLIDYDEVQRLATEHKPKMVIAGFSAYSQKIDWARFRAIADSVGAYLFVDMAHVAGLVAAGVYPSPMDHAHVVTSTTHKTLRGPRGGIILAKGAGEDLVKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPEFKTYQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITVNKNSVPNDPRSPFVTSGLRLGTPAITTRGYQEQDCVDLANWIADVLDAPADDAVLAKVRDAVTAQCKKYPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HARB1_RAT
Sequence: MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGASLSRPTQRSRAISPETQILAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIHFPADEAAIQSLKDEFYGLAGMPGVIGAVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLVVCDIRGALMTVETSWPGSLQDCAVLQQSSLSSQFETGMPKDSWLLGDSSFFLHTWLLTPLHIPETPAEYRYNRAHSATHSVIEKTLRTLCCRFRCLDGSKGALQYSPEKSSHIILACCVLHNISLEHGMDVWSSPVTGPIEQPPEGEDEQMESLDLEADRIRQELILTHFS
What is the function of this protein?
Transposase-derived protein that may have nuclease activity (Potential).  Does not have transposase activity (By similarity).
What are the official names of this protein?
Putative nuclease HARBI1, Harbinger transposase-derived nuclease.
What is the protein family that this protein belongs to?
Belongs to the HARBI1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Interaction with NAIF1 promotes translocation to the nucleus.
Protein: Y941_METKA
Sequence: MRVGIALSGDVPGAAERVLEAVERADVDVVVYHNVELDADVEEVRAKDPGRALVEDLVEGRLDAAVRGAVSGRCVRELVDALDLPFTGRSTVLEAEGRRVLLAPVGIDEGWEVESLVKLGELAARFHRRLTRREPSVAVVSSGRLEDFGRRSEIDRWLADGELVARLLKERGMEVEHVGILVEEALERDVVLFVNGVLGNLTFRCLSLVAGFRSHGAPVLAALERGVVFVDTSRAQRASGYARALRLAAELAGG
What are the official names of this protein?
Uncharacterized methyltransferase MK0941.
What is the protein family that this protein belongs to?
Belongs to the MtxX family.
Protein: GBRA6_MOUSE
Sequence: MVLLLPWLFIILWLENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKTEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQSQKAERQAQTAATPPVAKSKASESLQAEIVVHSDSKYHLKKRISSLTLPIVPSSEASKALSRTPILKSTPVSPPLLLPATGGTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEVSSTVE
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-6, GABA(A) receptor subunit alpha-6.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: WRK76_ORYSI
Sequence: MDAAWRGGVGCSPVCLDLCVGLSPVREPSAARHELLDRPAGCRGGGDSKSMTNDEAKILEAKVTQMSEENRRLTEVIARLYGGQIARLGLDGSASPPRPVSPLSGKKRSRESMETANSCDANSNRHQGGDADHAESFAADDGTCRRIKVSRVCRRIDPSDTSLVVKDGYQWRKYGQKVTRDNPSPRAYFRCAFAPSCPVKKKVQRSAEDSSLLVATYEGEHNHPHPSPRAGELPAAVGGAGGSLPCSISINSSGPTITLDLTKNGGAVQVVEAAHPPPPPDLKEVCREVASPEFRTALVEQMASALTSDPKFTGALAAAILQKLPEF
What is the function of this protein?
Transcription repressor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.  Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity).  Modulates plant innate immunity against X. oryzae pv.  oryzae (Xoo) (By similarity).
What are the official names of this protein?
WRKY transcription factor WRKY76, OsWRKY76.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-a family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACFR2_ARATH
Sequence: MAVPVLGGFPIFMVVRVLGFIIAALVLTWTVHYRGGLALSSDNKDHIFNVHPVMMVIGLILFNGEAMLAYKSVQGTKNLKKLVHLTLQLTAFILSLIGVWAALKFHIDKGIENFYSLHSWLGLACLFLFAFQWAAGFVTYWYPGGSRNSRASLMPWHVFLGISIYALALVTATTGILEKVTFLQVNQVITRYSTEAMLVNTMGVLILILGGFVILGVVTPVSGKDQVLTQ
What is the function of this protein?
Two-heme-containing cytochrome (PubMed:24449903).  Catalyzes ascorbate-dependent transmembrane ferric-chelate reduction (Probable).
What are the official names of this protein?
Transmembrane ascorbate ferrireductase 2, Cytochrome b561-1, Artb561-2, AtCytb561, Protein b561A.tha4.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: RLMG_VIBC1
Sequence: MKTELDLHDRSLTLHRFPKRSNETLQAWDAGDEYLINNVEGMALPDNQNIVVVNDNFGALACWFSDRHNVTLMSDSFISHKGAQQNLADNQCNQVSFLSTMDDIPENTDLVLMQLPKSNRHLVWLLSQLRKTLPASCPIVAVNKAKEIHTSTLKLFEKYLGETKTSLAWKKHRLVFSTANAQPVIDVDPMTIWGIEGEGIQLKNLPNVYSGESLDLGARFMLQHLPQDPTLKHVIDLGCGNGLLSVKMGQLNPQARLTSVDESFMAVESAKQNLLDNLGDARDIQCIANNCLDGFTPDCADMVMCNPPFHQQQAITDHIAWQMFCDAKQILNQGGKLLVIGNRHLGYDAKLKRLFGDKNVKLVASNNKFVILQATKNPAKLGAKQ
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U512M_DICDI
Sequence: MGYPESISSISNSTGSMGSSISASNLNGFASNDNSISCFDGGCGGGLGGWGGLRGWGGIGGFNGGCEGCGSSNTNIINLDIDIGRSHRRCC
What are the official names of this protein?
UPF0512 protein M.
What is the protein family that this protein belongs to?
Belongs to the UPF0512 family.
Protein: JIP5_YEAST
Sequence: MAKSKKKTDVVDSTNLPILELLSLKAPIFQSLLHPELPIIITGFGTGHIVCHRYDPAKLQSHLDRRRRIDTATTGKDAKKGVCPWIRLDIDLETGDLKFVDIEEQQQQKQTGKDEDLGVKTLWKTKRHKGSVRAMCFDSKGDNIFSVGSDNVLKKANTMTGKVVKKVNLSSLFNSEEKKNDKFTKLCASQTHPFILIGDESGNIHVINSENLALSNSIRSIHFGDSINDIFHFDKRSAYKFISLGQTTLAYFDVRDKDAKPNVAGNEDGKILISDDQEDEVLCGCFVDPEVADTLLCGMGEGIVTVWKPNKNDLEDQMSRIKISKDESIDCIVPTLQDDNCVWCGCSNGNIYKVNAKLGKVVEIRNHSELDEVSFVDLDFEYRVVSGGLENIKIWELSSDDVEENASVESDSDEPLSHSDEDLSDDTSSDDETTLVGLSKEELLDELDKDLKEDHQEEKESNSKSVKKRKIMKENNKKKDLYEHGIKKFDDL
What are the official names of this protein?
WD repeat-containing protein JIP5, Jumonji domain-interacting protein 5.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS7_SALRD
Sequence: MSRNEAPEQRTTQPDPVYRDDMVSRFVNAIMRDGKKSLARRIVYDTFDVIEERTGEEEGLEVFKKAVNNAAPLVEVRSRRVGGATYQVPTEVRPERRITLAFRWIIQYARARNEKSMVNRLASELVDAARGEGGAVKKKDDTHRMAESNKAFAHFQF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: LPXA_LEPCP
Sequence: MAQIHPTAIVDPAAELADSVVVGAYAVIGPQVRIGAGTTIGPHCVIEGRTTIGVDNRFFQFSSIGALPQDMSHDGEITELVIGDRNTVREFCTFNTGTRKEDGVTRVGSDNWIMAYVHLAHDVRLGSHCVLANNATLAGHVHVGDWATIGGLSGVHQFVHIGAHAMIGFQGHVSQDVPPYMTVDGNPLTVRAVNLTGLRRRGFSNERIGVIRQMHKLLYRDSLTLEQAVEAVGALRGQQAEAQSDADIAVMLDFIAGAKRGLVR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_STAES
Sequence: MEYKDIATPSRTRALLDQYGFNFKKSLGQNFLIDVNIINKIIEASHIDCTTGVIEVGPGMGSLTEQLAKNAKKVMAFEIDQRLIPVLKDTLSPYDNVTIINEDILKADIAKAVDTHLQDCDKIMVVANLPYYITTPILLNLMQQDVPIDGFVVMMQKEVGERLNAQVGTKAYGSLSIVAQYYTETSKVLTVPKTVFMPPPNVDSIVVKLMQRQEPLVQVDDEEGFFKLAKAAFAQRRKTINNNYQNFFKDGKKNKETIRQWLESAGIDPKRRGETLTIQDFATLYEQKKKFSELTN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.