PharMolix/UniProtQA huggingface dataset:
Protein: RBS_NEODN
Sequence: MRLTQGTFSFLPDLTDEQINKQLTYIVSKGLSANVEYTDDPHPRNSYWELWGLPLFDVKDASAVMYEISSCRKAKPNYYVKVNAFDNTRGIESCVMSFIVNRPANEPGFLLQRQDFEGRTMKYSLHSYATEKPEGARY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MRAZ_TREDE
Sequence: MTGEYKNTLDEKGRIMFPAKIRAELPDSNLVITRGVGNCLWIFTADKWKKFSDEIMKKTSLFKAQSLLVMRRLIAPAQEIEVDKNGRISIPQSLRECAGLEKDCIILGLGKCFELWDLKQYEKYLKESEPDFSEAAEALGEIGF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MNMA_UREU1
Sequence: MEVNTKKRVVIGLSGGVDSSVSALLLKQQGYEVIGLFMANWDTVANFENNRESDKKHQGCESELDYQDAQAVAQKIGIPLYRVEFIKEYWNNVFEYFLSEYQKNRTPNPDILCNQFIKFDSFLNYAKNELKADYIAMGHYAKVKHTNNLSYLLKATDVNKDQTYFLCNLKQTQLQNALFPIGDLTKQQVRTIAKEYGLVTANKKDSTGICFIGERNFKYFLENYIPNQPGEIVNIVNNQIVGHHMGTMYYTIGQRKGLNLGGMNERMFVCEKDINKKIIYVSPLSLEDQYLISNQALVENMNFIEPYNPQIPISVRFRHRQNLVVVNSFLCIENTNNVLINYEPAKAITPGQYAVFYQNDHCIGGGVIAQTNANHKKINF
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y481_BUCA5
Sequence: MKTKLREMLRFPCFFTYKIIGLAQPELIDQIIKVIQIQIPGDYTPQVKSSNRGNYLSVSITICAKNFEQIECLYHEISKINIVRMVL
What are the official names of this protein?
UPF0250 protein BUAP5A_481.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: SYR_BLOFL
Sequence: MNIQYLLLQRVHEALTLINTKSFLNLIQVQQSNHIRFGDYQINGMINISKHLQIPIKDFSNIFIKTINLKGIAKIIKFEPPGFINIFLSPTWIENKINHIIDLPKLGIDLIPSKNIVIDYSSPNIAKEMHVGHLRSTIIGDSIARILSFLGHNVIRSNHIGDWGTQFGMLIAYIKKHKINYLSLNDSQQISMLEYYYQESKKEYDSDPNFAELSRKYVVKLQKGDVYCRKIWKYLVDISISNNQKIYDRLNVTLKKKDIMGESMYHDMLPYIITDLKNKKLAVTSDHATIVFLNQNKNSKKNNPFGVIIQKKDGGYLYSTTDIACIKYRCETLHADRIIYYIDSRQKQHLMQAWEIAYQAGYITKAVVFEHHVCGMLLDKNKKPFKTRSGNTIKLITLLNEAFNKAYNLILNKNLNLEYKKINHLAHIISIGAIKYSELSKNRTTNYIFNWDKILNFDGNTAPYIQYAYTRISSIFKKINHRSELQEKKYQIFLSSQEEILLAICLLQFHETLITVADRGTPHILCGYLYKLSTLFSLFYEHCPILKTECTYTKYSRLKLSFITAQILKKGLNLLGIETSEYM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_NEIMB
Sequence: MSFDNYLVPTVIEQSGRGERAFDIYSRLLKERIVFLVGPVTDESANLVVAQLLFLESENPDKDIFFYINSPGGSVTAGMSIYDTMNFIKPDVSTLCLGQAASMGAFLLSAGEKGKRFALPNSRIMIHQPLISGGLGGQASDIEIHARELLKIKEKLNRLMAKHCDRDLADLERDTDRDNFMSAEEAKEYGLIDQILENRASLRL
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_COXB1
Sequence: MIAMNTPDFQRMKKDNKKISMVTCYDYWSACIISQSNVDCILVGDSLAMVMYGHSTTLPATVEIMAQHIQAVSRGAPNKFIIGDMPFCSYRKDLTTSMNAVERLMQAGAQAIKLEGADAHNLKFIHHVVKSGIPVIGHLGLTPQSIYTLGGFKVQGKEPSAAKKLMADAKALAETGCFAVVLECVPSELAELITNSISIPTIGIGAGPATSGQVLVLQDLLGTNNQFQPKYLKKFLNGFELIKKALDDFDQEVKTSTYPHLETHCY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_SHESM
Sequence: MSKINLLLLCGGGSAEHDISLLSANYFETSLAKSEQFNVLRVVLDKFGQYQTAAGDDCELTNNREIRFRDETKAPWPVDYVIPCIHGYPGETGDIQSYFNLIQLPYFGCESEASSNCFNKITAKMWFSALGIPNTPYIFLNQYDDEAIAQTQAALENWGSIFVKAASQGSSVGCYKVDDSSKVAGVLKDAFGYAPYVIVEKTIKARELEVAVYEYQGEVVATLPGEIICDSNTFYTFDEKYAKSSKARTDVVAQNVPTDISEQIRAYAIKAFKGMKLRHLSRIDFFLTQDNEILLNEINTFPGSTPISMFPKMLQNHGHDFTEYLSLVINGQLAAK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_MYCCT
Sequence: MSRIERIFAREILDSRGTPTVEVEVWTEFGGYGCAKAPSGASTGVNEALELRDGDKARYNGKGVLKAVKNVNEIIAPELIGIDALDQLTVDRKMLDLDGTEFKTKLGANGILAVSLAVAKAAASELDIPLYKYLGGVQAKKLPVPMLNVINGGEHADSAIDFQEFMIMPVGAKSFSEALRWSSETFQALKSLLKSKKDITAVGDEGGFAPNFEWAYEKHDLESFKKKTPAEIALDLLVDAIKKAGYKPGKDGIMIAMDCASSELYLEDKKYHFKKIEKVTNQEWSLTSDEMISYLEKLVNNYPIISIEDGLAETDWEGFTKLTQKIGDKVQIVGDDLFTTNPKFIKQGINKKAANSTLIKLNQIGTLSETVEAITMTQKAGWTAVVSHRSGETEDTTIADLAVAFNTGQIKTGSMSRSDRIAKYNRLLQIESELGQNAIYDGLEAFYNLNK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: IBL1_ARATH
Sequence: MQPTSSMNEEFLKKWQMGLQIFRPSIDNTSVHERKKAIKLSADVAMASLRKGTTCWSRALIEKTATEDNFLVRQMLSGIKAETLINKKLPKKTVCHRKIVRRSKKILRRKSKSASEEAAAKAKRLVKRRTQGLRNVVPGGELMSNDVLLLQETLDYIVSLQTQVNVMRSIVDAAEAEIER
What is the function of this protein?
Functions redundandly with IBH1/BHLH158 in a regulation node known as the incoherent feed-forward loop (FFL).  Acts as transcriptional repressor that negatively regulates cell and organ elongation in response to gibberellin (GA) and brassinosteroid (BR) signaling.
What are the official names of this protein?
Transcription factor IBH1-like 1, AtIBL1, BHLH transcription factor eta, bHLH eta, Basic helix-loop-helix protein 159, AtbHLH159, bHLH 159, bHLH transcription factor bHLH159.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYM_THIDA
Sequence: MSRQILVTSALPYANGSIHLGHLVEYIQTDIWVRFQKMRGTNCRYMCADDTHGTAIMLRAEKEAITPEALIQRVWAEHTRDFAGFHIGFDHYYSTHSDENREHASKIYLALKDAGLIEVKTIAQLYDPVKNLFLPDRFIKGECPKCGAADQYGDNCEVCGATYSPTELKNPVSAVSGATPVHKDSEHYFFKLGDCEAFLREWTTSGTLQAEAANKMQEWFAAGLNNWDISRDAPYFGFEIPDAPGKYFYVWLDAPVGYMASFARYAKDHGLDFDAWWGKDSKTELVHFIGKDILYFHALFWPAMLKFSGHRLPTAVYAHGFLTVNGQKMSKSRGTFITASSYLDQGLNPEWLRYYYAAKLNGTMEDIDLNLDDFVARVNSDLVGKFINIASRTAGFIHKKFDGKLADGVGNIELIGEFQAAADTIAAHYEARDYAKALREIMALADRANQYVADEKPWELAKDDAAVYRLHEVCTVALNLFRLLTLYLKPVLPKLAGEVERFLDIPALTWKDARSLFIRQAINAYSHLMTRIDPKSIEAMVDANKQNLEPTPAPAPARHAEAQAHAAQAVEAPKTETISIDDFAKVDLRIARIANAEHVEGADKLLRLTLDVGELGPRQVFAGIKSAYAPEALVGRLTVMVANLAPRKMKFGMSEGMVLAASNPDGHKDDVPGLFILSPDSGAEPGMKVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_STAAN
Sequence: MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_ECOL5
Sequence: MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL61_ARATH
Sequence: MPAAKRTPKVNRNPDLIRGVGKYSRSQMYHKRGLWAIKAKNGGVFPRHDAQPKVDAPVEKPAKFYPAEDVKKPLVNRRKPKPTKLKASITPGTVLIILAGRFKGKRVVFLKQLSSGLLLVTGPFKINGVPLRRVNQAYVIGTSTKIDISGVNTEKFDDKYFGKVAEKKKKKTEGEFFEAEKEEKKEIPQEKKEDQKTVDAALIKSIEAVPELKVYLGARFSLSQGMKPHELVF
What are the official names of this protein?
60S ribosomal protein L6-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL6 family.
Protein: ZP3_MOUSE
Sequence: MASSYFLFLCLLLCGGPELCNSQTLWLLPGGTPTPVGSSSPVKVECLEAELVVTVSRDLFGTGKLVQPGDLTLGSEGCQPRVSVDTDVVRFNAQLHECSSRVQMTKDALVYSTFLLHDPRPVSGLSILRTNRVEVPIECRYPRQGNVSSHPIQPTWVPFRATVSSEEKLAFSLRLMEENWNTEKSAPTFHLGEVAHLQAEVQTGSHLPLQLFVDHCVATPSPLPDPNSSPYHFIVDFHGCLVDGLSESFSAFQVPRPRPETLQFTVDVFHFANSSRNTLYITCHLKVAPANQIPDKLNKACSFNKTSQSWLPVEGDADICDCCSHGNCSNSSSSQFQIHGPRQWSKLVSRNRRHVTDEADVTVGPLIFLGKANDQTVEGWTASAQTSVALGLGLATVAFLTLAAIVLAVTRKCHSSSYLVSLPQ
What is the function of this protein?
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy.  The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4.  ZP3 is essential for sperm binding and zona matrix formation.
What are the official names of this protein?
Zona pellucida sperm-binding protein 3, Sperm receptor, Zona pellucida glycoprotein 3, Zp-3, Zona pellucida protein C.
What is the protein family that this protein belongs to?
Belongs to the ZP domain family. ZPC subfamily.
What are the subcellular locations of this protein?
[Processed zona pellucida sperm-binding protein 3]: Zona pellucida. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: ACT_YEAST
Sequence: MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ZSCA4_PANPA
Sequence: MALDLRTIFQCEPSENNLGSENSAFQQSQGPAVQREEGISEFSRMVLNSFQDSNNSYARQELQRLYRIFHSWLQPEKHSKDEIISLLVLEQFMIGGHCNDKAGVKEKWKSSGKNLERFIEDLTDDSINPPALVHVHMQGQEALFSEDMPLRDVIVHLTKQVNAQTTREANMGTPSQTSQDTSLETGQGYEDEQDGWNSSLKTTQVNENITNQGDQIVSLIIIQEENSPRPEEGGVSSDNPYNSKRAELVTARSQEGSINGITFQGVPMVMGAGCISQPEQSSPESALTHQSNEGNSTCEVHQKGSHGVRKSYKCEECPKVFKYLCHLLAHQRRHRNERPFVCPECQKGFFQISDLRVHQIIHTGKKPFTCSICKKSFSHKTNLRSHERIHTGEKPYTCPFCKTSYRQSSTYHRHMRTHEKITVPSVPSTPEAS
What is the function of this protein?
Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency.  Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation.  Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity).
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 4.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RL30_ACIF2
Sequence: MSKHLRITLVKSLIGVAEKHRRVVAGLGLRHTHHSVERLDTPEIRGMVNKVPYLLRWEELS
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: LACD_LISIN
Sequence: MVQITKGKFDGLQRLSNDKGVIAALAIDQRGSLKKMIQQAKGTENKKDVEDFKQLVSEELTPYASAILLDLEYGTPAIKARHEGSGLLTSYEKTGYDATTPGKLPDLIEDLSALRIKENGGDAVKILVYYDPDEPAEINEIKYAFLERIGAECRAVDIPFFLEPITYDAKVTDSGSLEYAKLKPAKVKASIKEFSKPRYGVDVLKLEVPVNFKYVEGFAEGEVAYTQDEAARHFEECSDLSPLPFIYLSAGVTSEMFHKTIQFANQHNVQYSGVLCGRATWADGIEVYGKQGDDALREWLRTQGKENITSLDKLLDEGAVPWWTKYGSFEDVHVVEKQ
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase, D-tagatose-1,6-bisphosphate aldolase, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: AROA_LISMO
Sequence: MKLITNKQGLVGAITVPGDKSMSHRSIMFGAIAEGKTVIRHFLRADDCLGTIKAFKALGVKIEETDEEIIVHGTGFDGLKQADGPLDIGNSGTTIRLMMGILAGRDFDTVILGDESIAKRPMNRVMLPLQQMGAKMHGKDGSEFAPITITGKQSLKRMEYHMPVASAQVKSAIIFAALQAEGETIIHEKEKTRDHTEHMIRQFGGEIEMDGLTIRVKGGQKFTGQEMTVPGDVSSAAFFIVAGLITPGSEIELTHVGLNPTRTGIFDVVKQMGGSLVVKDSSRSTGKLAGTVVVKTSKLKGTEIDGDIIPRLIDEIPVIALLATQAEGTTIIKDAAELKVKETNRIDAVATELNKMGADITPTEDGLIIHGKTPLHAANVTSYGDHRIGMMLQIAALLVEEGDVELERPEAVSVSYPTFFEDIRSLLK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYFP2_XENLA
Sequence: MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCNEVKRLCHTERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIETSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMVKGLQVLMGRMESVFNQAIRNTIYAALQDFAQSSLREPLRQAVRKKKNVLISVLQAIRKTVCDWEAGREPPNDPCLRGEKDPKGGFDINVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVQAIEEFHKQSFFFTHLLNFSEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLSDQIFAYYKAMSGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLDINRLTHRLLSKHLTLDSFDAMFREANHNVSAPYGRNTLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTVLQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVELHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCAIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEIFAVLNKYMKSVESDSSTVEHVRCFQPPIHQSLATTC
What is the function of this protein?
Involved in T-cell adhesion and p53-dependent induction of apoptosis.  Does not bind RNA (By similarity).
What are the official names of this protein?
Cytoplasmic FMR1-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the CYFIP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_HALS3
Sequence: MYERGAFVADHVEPVADDQIQPNGVDLTVDAVLEQTEPGRIDTDGKTIGDRSPVTPTADEDSTDTTVTIQPGTYILQYAETITIPENHVGFVYPRSSLMRNSCMLHSAVWDAGYTGRGEGLFEVHHEITIARGARVAQLVLATGDHENTYDGSYQHERTDTRPGE
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Probable deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family. Archaeal dUTPase subfamily.
Protein: GLYA3_COLP3
Sequence: MKNTYTSGELEQFFSSDLSSTDGAVQVAIDLEEARQNQQIELIASENIVSKAVMEAQGTVLTNKYAEGYPGRRYYGGCEHVDLVETLAIDRAKLIFKADFVNVQPHSGAQANGAVMLALVKPGDTILGMSLDAGGHLTHGAKPAQSGKWFNAIHYGVRKDDMRIDYDQVLALAIEHQPKMIIAGGSAIPRQIDFAKFREIADQVGAILMVDMAHIAGLVAAGAHQNPLPFADVVTTTTHKTLRGPRGGLILTNNPDVAKKINSAVFPGLQGGPLMHVIAAKAVALGEVLEPSFGAYIKQVLSNARVLASTLQQRGCDIVTDGTDTHLMLVDLRPKGLKGNTTEESLERAGITCNKNGIPFDSEKPMVTSGIRLGTPAGTSRGFGNDEFELIGQWIGDVLDGLVANPEDNSVAEQKVLQQVQQLCLRFPLYS
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 3, SHMT 3, Serine methylase 3.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_FRATT
Sequence: MNEYNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGTLHMGHVRNYTIGDVIARYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSREITTCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNWDPVDQTVLANEQVVDGRGWRSGALVEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQEIEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLATQEKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQVIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRIHDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAGSPLKDIPEFINVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEANYWLPVDKYIGGIEHAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVLKDGAKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETGVEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQFNTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNLGEDILHTSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQVVKVIYVPQKLINIVIK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHA_ECOLI
Sequence: MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
What are the official names of this protein?
Succinate dehydrogenase flavoprotein subunit.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VAT1_TETCF
Sequence: MTGEEVKEPKEQQEITEVKEQEPEISYNAIVLNGVGGYDKVKVEVKKGVPTLKSDEILVRVQACGLNFSDLLVRQGAFGKHHSLGTECAGVVEAIGDLVIDRKVGDKIIMLNIDGGLWTELVVTTVNRTFLMPDGMSFQEAAAISVNYTAAYVMIYDFANLRPSQSILIHMAAGGVGIAATQLCKLVHDVTIFGTASPSKHETIKENGVTYPIDYTTLDYAEEVRKIAPKGVDIVLDPLGGADDSKGFGLLKPLGKLVLYGSANQVTAPKRSSLAAAKVWWHKFNIDALQLINSNKAVCGFHLGRTDPDHVAEVIRKLISLYKEGKIKPKVDSVWSFEQVGDAMRHMRNTRTLEKSSWSLKSRQLMPQLEIKSVSKRQG
What is the function of this protein?
May play a central role in the functions mediated by specific classes of synaptic vesicles.
What are the official names of this protein?
Synaptic vesicle membrane protein VAT-1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane.
Protein: XERC_MYCBP
Sequence: MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.