PharMolix/UniProtQA huggingface dataset:
Protein: Y500_METJA
Sequence: MSFMIIEEIKERALNLLSEKEEDFKVIDFSFALPYSYVLIESNGKKALGVAMTLLEEYRGHGNRKDLNINKNLEEFINMADSFDIVERTLGVAAINAVSQYYFNFEANGKDAAELVLNRDDIKKIAFVGNMIPVVNMLKKSEKFDIYVFERSPSLLMDGVLSDAFEYRLLPEMDAVFISGTTLLNDTLDFVLDRAKNAKLKILVGPTAQSLPELFKGFGITHIASTKIIDVDKALLYLKFASSSMLFKGASKKYTMEVE
What are the official names of this protein?
Uncharacterized protein MJ0500.
Protein: MAK_MYCTA
Sequence: MTRSDTLATKLPWSDWLSRQRWYAGRNRELATVKPGVVVALRHNLDLVLVDVTYTDGATERYQVLVGWDFEPASEYGTKAAIGVADDRTGFDALYDVAGPQFLLSLIVSSAVCGTSTGEVTFTREPDVELPFAAQPRVCDAEQSNTSVIFDRRAILKVFRRVSSGINPDIELNRVLTRAGNPHVARLLGAYQFGRPNRSPTDALAYALGMVTEYEANAAEGWAMATASVRDLFAEGDLYAHEVGGDFAGESYRLGEAVASVHATLADSLGTAQATFPVDRMLARLSSTVAVVPELREYAPTIEQQFQKLAAEAITVQRVHGDLHLGQVLRTPESWLLIDFEGEPGQPLDERRAPDSPLRDVAGVLRSFEYAAYGPLVDQATDKQLAARAREWVERNRAAFCDGYAVASGIDPRDSALLLGAYELDKAVYETGYETRHRPGWLPIPLRSIARLTAS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate.  Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity).
What are the official names of this protein?
Maltokinase, MaK, Maltose-1-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
Protein: CLP1_MACFA
Sequence: MGEEANDDKKPTTKFELERETELRFEVEASQSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSGRTEVAYVSKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSIQAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGSGYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGCFYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDLK
What is the function of this protein?
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double-stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids.  dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component.  Plays a key role in both tRNA splicing and mRNA 3'-end formation.  Component of the tRNA splicing endonuclease complex: phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA.  Its role in tRNA splicing and maturation is required for cerebellar development.  Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation.  Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC).  However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing (By similarity).
What are the official names of this protein?
Polyribonucleotide 5'-hydroxyl-kinase Clp1, Polyadenylation factor Clp1, Polynucleotide kinase Clp1, Pre-mRNA cleavage complex II protein Clp1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_LARHH
Sequence: MAITKDDILEAVGAMTVMELNDLVKAFEEKFGVSAAAMAVAAPAAGAAAAAEEKTEFDVVLTAAGDNKVNVIKVVRALTGLGLKEAKDMVDGAPKTVKEGVSKADAEAMLKQLTEAGAKAEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: FBID_CHLSY
Sequence: MIGIVIPIKRLHLAKSRLIDLLDPADRQQLVVTMVRHVITTARQAVSYLSIPARIWLVSPEPTLATDSEGIEWLPDNQEELNAALTEARQRIQAAGVQIMMVLAGDLPFVTVRDLILLSEALTDNDVVVAPDQHGQGTNALGLHLPSQLPFGFGPDSAGYHLRTAARLGLRASLISTPTLAFDLDDGERLQQYYRCIASCDNFAR
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: HXA7_MOUSE
Sequence: MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGPGAGAFASTVPGLYNVNSPLYQSPFASGYGLGADAYNLPCASYDQNIPGLCSDLAKGACDKADEGVLHGPAEASFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDESQAPTAAPEDAVPSVSTAADKADEEEEEEEEEEEEEEE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A7, Homeobox protein Hox-1.1, Homeobox protein M6-12, M6.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YGGU_SHIFL
Sequence: MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN
What are the official names of this protein?
UPF0235 protein YggU.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: SCTG_YEREN
Sequence: MSRIIALIISFLLVGCATPPMPAQRIVGEVRMSRPLSRTAHIDVSIFGLYEGKVREVQRTRFETGNLPLFFSIKLNPAQRGEGELYLRSTLSFPERGVQAVAQQKLIGKNKVVLQMIPKTCYPNCQSPNTR
What is the function of this protein?
Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:9427408, PubMed:15292137).  Pilot protein that is required for the proper localization of the secretin YscC/SctC in the outer membrane (PubMed:9427408, PubMed:15292137).  Also required for efficient oligomerization of YscC/SctC and stabilization of the oligomers (PubMed:15292137).
What are the official names of this protein?
Type 3 secretion system pilotin, Lipoprotein VirG, Pilot protein YscW.
What is the protein family that this protein belongs to?
Belongs to the ExsB/YscW family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=Association with the outer membrane is a prerequisite for function in the biogenesis of YscC/SctC.
Protein: DAPE_COXB2
Sequence: MSETLNLLKQLIERPSITPNDAGCQTILIDRLKSVGFQCEHLPFGEVHNFWAWHGHQSPFIIFAGHTDVVPPGDETQWHSPPFTPTEKNGYIYGRGAADMKSGLAAMVVAAENFVKQNPDHNGTIGFIVTSDEEGPAENGTQKVVDYLQQKNIKLDYCIVGEASSNEKLGDAIKIGRRGSMHGELTIIGKQGHIAYPHLADNPIHRSFQAFEALAKTKWDEGNEHFTPTSFQFYNVEAGAGAANVIPATLKAKFNFRFAPIHTTQQLQQKVERILNYYQLNYDIQWNVSSQPFFSGNGRLATFVRQAIQEICHLNTEPNTYGGTSDGRFIATTGCEVIELGPVNKTAHHVNENICIADLEKLTDIYFRTLQLLT
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: KUP_VIBCH
Sequence: MKPAKQTTASLAFLAMGIVYGDIGTSPLYAFKEVFFSHHPLAINPDNVLGILSLVFWAFVLIVSIKYLLLVTRADQNGEGGILTLSAIAQQSAPKPWQRIAMLLGILATGFFFGEAVITPAMSVLSAVEGIAVAQPDLAPYVLPIAMMIIVALFAVQAMGTERIGRFFAPVMLLWFLVLALLGAHAIWHAPQVLRALNPAYAVHFVLLYGQHTLFILGLVVLSVTGVEALYADMGHFGIKPIRIAWFALVMPSLLLNYFGQGAYLLTLSAPTGSTFFSLAPKAWLWPLILLATFATVIASQAVISGIFSLARQAINYGYLPPMKIAHTSEHSQGQIYVPAANMLLFVAVIFVMLRFRSSANLAAAYGIAVTAIMMISSLLLVLVARYQWQWRWPRVVTIGIVFIGMDSLLLASTSTKLMEGGWLPLLLGCVVFIVMYIWQQQRQRLLEIAGNELSVSAMIQSLEEESFQRAAGTAVYLSRSLNHVPRSLLHNIKYNKTLHERNVLMTFQYEAVPRVHPCRRAEIEQVSASFWQVVIHIGYQEEPDMAQVMHCCGLKGLYLHPNETLFLLSSERLKVQKLGMWHDLKVWFFIQMSKHALRTSERLNIPPDRLIEMGVYREM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL36_WIGBR
Sequence: MKVRTSVRKLCRNCKIVKRNRVIRVLCSVDAKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RNH3_MYCPN
Sequence: MQHANTTALYLIGSDESGKGDSFGGIAVSAVLIHKDKINTLHQIGVGDSKQFNDYQIKALVPKIKAAVHDQVTLSVDAKTYNQLVQSFKNVNVMLTFLHCKVYHQLLQQNKLTAQQCDISIDEFANVKLFTQYTQKLTSLQNELKELVIPNHFLIRGESYSKVIAAASILARAAFIAQMEQLSHQYGVQFPKGSAHGIVEALHLLKTKRQFHKFAQYSAVCKTTFKNVASFLKQLA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VME1_IBVH1
Sequence: MSNETNCTLDFEQSVELFKEYNLFITAFLLFLTIILQYGYATRSKFIYILKMIVLWCFWPLNIAVGVISCIYPPNTGGLVAAIILTVFACLSFVGYWIQSIRLFKRCRSWWSFNPESNAVGSILLTNGQQCNFAIESVPMVLSPIIKNGVLYCEGQWLAKCEPDHLPKDIFVCTPDRRNIYRMVQKYIGDQSGNKKRFATFVYAKQSVDTGELESVATGGSSLYT
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the gammacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: RL5_CHICK
Sequence: MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNKFGLDKIYEGQVEVTGDEYNVESVDGKPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNITPDGMEEMYKKAHAAIRDNPVHEKKPKREVKKKRVNSTKMSLAQKKDRVAQKKASFLRAQERAADS
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs.  It also couples ribosome biogenesis to p53/TP53 activation.  As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53.
What are the official names of this protein?
60S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: RL36_PARXL
Sequence: MKVMASVKRICRNCKIIKRKGVVRVICSSDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PLDB_ECOLI
Sequence: MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVRFVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHLGFDVLIIDHRGQGRSGRLLADPHLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIALTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRYRRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNRMHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSGNRSTEV
What are the official names of this protein?
Lysophospholipase L2, Lecithinase B.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PUR5_XANC5
Sequence: MTYRDAGVDIDAGNALVERIKPLVKRSFRPEVMGGLGGFGALFDLSGKYKEPVLVSGTDGVGTKLKLAQQLGRHDTIGIDLVGMCVNDVLVQGAEPLFFLDYFATGKLDVDTAAAVVGGIARGCELSGCALIGGETAEMPDMYPPGEYDLAGFTVGAVEKSQLLDGAQVRDGDVLIGIASSGPHSNGYSLIRKIYERAGAPAEHVLDDGTKLIDALMAPTALYVKPVLSLLKSHGEAIHAMAHITGGGLTENIIRVIPQGLGLDIDATAWTLPPVFAWLQREGAVADAEMWRTFNCGIGFVLIASLEQAATLEQALDAQSLAHWRIGQVVPAHGDERVRIG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNO1_HUMAN
Sequence: MESEMETQSARAEEGFTQVTRKGGRRAKKRQAEQLSAAGEGGDAGRMDTEEARPAKRPVFPPLCGDGLLSGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKETKDVSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).  Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA (PubMed:25851604).
What are the official names of this protein?
RNA-binding protein PNO1, Partner of NOB1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
Protein: G4P_BPIKE
Sequence: MKLQAEKKLIFGYVALCFLMTLGIAFNVLADPVNLNNAPVRSFVQWYSQKSNKAVVVNPDVKGNITVFNADVNQANIDDFFKSVLNANGFVLMAGDPSGVSTPSKLPSQQTDNDDDYEDSADYVPVGDSVPVSAQPQKPLDLTVRNFKLTRVRSSDVLPLAKIFVDSNGGGDVIDYPGNNSLLVSGSAAIMNALADFITSIDVARDQVLIQSLMFETSLVNGVDLSFAAGSASGDKVAGGFNTSALGTALSTAGGSFGIFNGNVLALSIQAVKNDSNSKVISTPRILTQSGQTGYISVGQNVPFVTGKVTGEAANVNNPFQTIERRDVGVSLKVTPVVMGNGQLVLTIDTKADSLTSQMTASDIITNQRHMQTTVQIKDGQTLLLGGLIDSNTTDGNRSVPWFESVPVIGWLFRSHSDSHNERTMFVLLTAHVIKAL
What is the function of this protein?
Acts in the assembly and extrusion of the bacteriophage by forming a channel across the host outer membrane.  This channel is just large enough to allow a newly synthesized phage particle to pass through.  Extrusion is a process of concomitant assembly and secretion and takes place at specific assembly sites where host inner and outer membranes are in close contacts (By similarity).
What are the official names of this protein?
Virion export protein, Gene 4 protein, G4P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G4P protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: IPDF_MYCTU
Sequence: MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETAAELSALGLGRVEHVVCDVTSTAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAPHGGVIVNNASVLGWRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINAVSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIAFLASDYSSYLTGEVISVSCQHP
What is the function of this protein?
Involved in the final steps of cholesterol and steroid degradation (PubMed:28377529).  Probably catalyzes the oxidation of the 5-OH group of (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA, leading to the formation of HIEC-CoA (Probable).
What are the official names of this protein?
(5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PURA_XANCB
Sequence: MGQSVVVLGAQWGDEGKGKIVDLLTEEIGAVVRFQGGHNAGHTLVINGKKTVLHLIPSGILRDDALCLIGNGVVISPAALIKEIGELESAGVEVRSRLKISPAAPLIMPYHIALDQAREKAAGGKAIGTTGRGIGPAYEDKVARRGIRIADLHYPAQLEELLRTALDYHNFVLTKYLGVEAVDFQKTFDEALAFGEYVQPMKSDVAGILHDLRKQGKRVLFEGAQGALLDIDHGTYPYVTSSNTTVGGALAGTGVGADAIDYVLGIAKAYATRVGGGPFPTELDDEVGQGIRDRGAEYGASTGRPRRCGWMDIVALKRAVAINGISGLCITKLDVLDGMEKLKVCIAYEYRGKRTEYAPLDAQGWEECTPVYLEFPGWTENTHGITEWDKLPVAARAYLRALEELAGCPISIVSTGPDRDHTMVLQDPFA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNO1_CAEEL
Sequence: MATSSSAFDDELPMEEGMPELLDDEDVPSTLPSLLEQNLDTAPKGDEFKLVKRKRKSGNAIDVVMEDVSQVDEDATADTADDSTGPKSSKRTKGVKGESRVVPVPKHRYTPLKDNWVNIFTPIVKNLGLQVRFNLKKRQVEIRNPVDREDTTDLQKATDFVRAFILGFEVNDAIALIRLDHLFLETFEVADVKHSLKGDHVSRAIGRIAGKDGRTKLVIENTTKTRIVVANTKIHILGAYQNLKLARNAVCSLILGSNPSKVYGSLRNMASRGAERL
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
What are the official names of this protein?
RNA-binding protein pno-1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ALLC_STUS1
Sequence: MKAYAVPFEKYVNLADARLGTRAISVTDDWFADVNRLFQPTPAVWKEGVFDDNGKWMDGWESRRKRFEGYDHAVIRLGVPGWIKGVDIDTSFFTGNYPPSASLEACFVADGDPSDATVWTEILPAVELKGNSHHYHEIAFDKPVSHLRFNIYPDGGVARLRVHGIPYRDWSSVGHNEQVDLAAALNGGRALACSDEHFGRMSNILNPNRGENMGDGWETARRRTPGNDWVIVALGHPGEIERVVVDTLHFKGNYPDSCSIQAAYVKGGTDSQIETQSLFWRELLPSQKLSMHAEHEFAGQIAKLGPVTHVRLNIFPDGGVSRLRLFGKVVK
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: ARLY_ECO24
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLDELQKFSPVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAMB2_YERPP
Sequence: MKTSLRTLSVALAAALVSPSVLAIEKIDFHGYMRAGVGVSSDGGLAEWQKTMVGRLGNESDTYGEIGLGAEVYKKEDVSFYLDSMVSMLSDGSNDSETTIGDDAQFGLRQLNLQIKGLIPGDKEAVIWGGKRYYQRHDLHIIDTKYWNISGSGAGIENYTVGPGAVSVAWVRGDANDVDTRITGDSDVNINYIDVRYAGFKPWAGSWTEVGIDYAMPNPTKQQKEYGGLYDADNAVMLTGEISQDMFGGYNKLVLQYANKGLAQNMISQGGGWYDMWHKTDEAKGYRVINTGLIPITDKFSFNHVLTWGSANDITEYTDKTNLISLVGRAQYQFTQYVRAIGEVGGFYQKDTYHNGSNYKQGGEKYTIALGLAEGPDFLSRPELRVFASYLNDSENGKPFEDGTSNDTWNFGVQVEAWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin 2, Maltose-inducible porin 2.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RL9_ELUMP
Sequence: MKVILRKDVKNLGMVGDIVEVKPGYGRNYLIPQGLAEVATEGAVKNWQLGAERRAKKIEAELKAAQAAASKLKDIVLTFTKSVNTEGVVFGSVNKADIYKALKELGHEIEKENIELNMPVKKLGETDVNIYFKPTVSAVIKVKIEPVVVEAK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GCH4_PARDP
Sequence: MTEARPVATERAYPALSREYPADFRVDDSYKASLPDLQNGPASLIVGARAPIQHVGISNFRLPIRYQTQEGGEIALETSVTGTVSLEADRKGINMSRIMRSFYAHAEKQFSMGVLEAALEDYKSDLGSFDARIMMRLSYPMRVESLRSGLSGWQYYDIALELSERAGQRLRIMHFDYVYSSTCPCSLELAEHARQMRGQLATPHSQRSIARISVVMQGDTLWFEDMVTLCRRAVATETQVMVKREDEQAFAELNAANPIFVEDAVRAFAAELMAEPRIGDFRVVASHQESLHSHDAVSVLTQGETFAHASLDPAIFAGLRA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: CIDA_STAAC
Sequence: MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.