PharMolix/UniProtQA huggingface dataset:
Protein: NRAM_INBLE
Sequence: MLPSTVQTLTLLLTSGGVLLSLYVSASLSYLLYSDVLLKFSSTKTTAPTMSLECTNASNAQTVNHSATKEMTFPPPEPEWTYPRLSCQGSTFQKALLISPHRFGEIKGNSAPLIIREPFVACGPKECRHFALTHYAAQPGGYYNGTRKDRNKLRHLVSVKLGKIPTVENSIFHMAAWSGSACHDGREWTYIGVDGPDNDALVKIKYGEAYTDTYHSYAHNILRTQESACNCIGGDCYLMITDGSASGISKCRFLKIREGRIIKEILPTGRVEHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTKTYLDTPRPDDGSIAGPCESNGDKWLGGIKGGFVHQRMASKIGRWYSRTMSKTNRMGMELYVKYDGDPWTDSDALTLSGVMVSIEEPGWYSFGFEIKDKKCDVPCIGIEMVHDGGKDTWHSAATAIYCLMGSGQLLWDTVTGVDMAL
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: EHD1_MOUSE
Sequence: MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQAVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSKRRHE
What is the function of this protein?
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis.  In vitro causes vesiculation of endocytic membranes (By similarity).  Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed:15930129, PubMed:20159556).  Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity).  Plays a role in myoblast fusion (PubMed:21177873).  Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (PubMed:24373286).  Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis.  Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29.  Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension.  Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis (By similarity).
What are the official names of this protein?
EH domain-containing protein 1, PAST homolog 1, mPAST1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Note=Preferentially associates with tubular recycling endosomes (By similarity). Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes (PubMed:21177873). Localizes to the ciliary pocket from where the cilium protrudes (By similarity). Colocalizes with BACE1 in tubulovesicular cytoplasmic membranes. Colocalizes with BACE1 and APP amyloid beta proteins in hippocampal mossy fiber terminals.
Protein: LCOR_MOUSE
Sequence: MQRMIQQFAAEYTSKTSSTQDPSQPNSTKNQSLPKASPVTTSPTAATTQNPVLSKLLMADQDSPLDLTVRKSQSEPSEQDGVLDLSTKKSPCASSTSLSHSPGCSSTQGNGRPGRPSQYRPDGLRSGDGVPPRSLQDGTREGFGHSTSLKVPLARSLQISEELLSRNQLSTAASLGPSGLQNHGQHLILSREASWAKPHYEFSLSRMKFRGNGALSNISDLPFLAENSAFPKMAHQTKQDGKRDMSHSSPVDLKIPQVRGMDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQNRKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQPRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKERLGTLKNPPKKKMKLMRSEGPDVSVKIELDPQGEAAQSANESKTE
What is the function of this protein?
Repressor of ligand-dependent transcription activation by various nuclear repressors.  Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR (By similarity).  May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'.
What are the official names of this protein?
Ligand-dependent corepressor, LCoR, Mblk1-related protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUXG_DROME
Sequence: MSKAHPPEVKKYMDKRMMLKLNGGRAVTGILRGFDPFMNVVLDDTVEECKDNTKNNIGMVVIRGNSIVMVEALDRV
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:18621711).  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  Is also a component of the minor U12 spliceosome (By similarity).
What are the official names of this protein?
Probable small nuclear ribonucleoprotein G, snRNP-G, Sm protein G, Sm-G, SmG.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: YL135_PLAF7
Sequence: MEEIENAHYQNLENFNDETSEDVNDTSDDINKNNDDNNKYDDNNVNVLDDKNKLENEEDNNNNDNMMIFSSILRYQRYKTKKGNIYFDFKNTNLSLNEKDMLVQSSNFYHLFDIKSLLCPHIYLNVSSHININISDYKNYLKRILNNDNVLDDKNENVKYSSCQEFIFEAVEQAEHIEVFTKVQIVKKLFLFLNQNVAEKMKNYIDNIPIINSNDYVLVQTNLKNDLLLGYVKGIKYNLFFEILNMKKCFHSFLNENIVIYEINEDKEGYFKTIDGKKYLKEQIVYEKKDLLKNLDFYSMYYCDYYFSSNSIIELEKKNNNNINCVNNNINSVNNNINSVDNNINNVDNNINSVNNNNNISDKITHKFEYNDYNDIHLFFSFNICIKSVKNNLFLHIIYNDNNLKNGDEYLNETFPHYEELNLYNKQFDINKMDKNLFKSNTFFINNLYYHLKCKLLCVFKFINMSDDDFMTDIHISQIKKRRYVNEQDSYMLYTFNIHTLSNEGMVYIFFCNLYISNMFKENNFEIRVHTYLHFQLNKQNSYKKLKLIKYSSKFLYSLCFKEKSDSKKKKKKNDHHERDSDNNNNDSNNNNYYNSNNNSNYCGSNNIIYGHDENFIFNSCDFNTLDQIKSGNYLIKDETINENFIFEVRNYKYTFILISSKCNIIIITLRKKKRKEEYNKKMSKYSSCSLNENVYMEGVEILNYCSSNNKNTNNIICNTIINKYNYEINNNIKNKNKSYILFEIVCFYENGEIQKYIYTCSLKNGNFEFFLNVKEDEKTKSINCKKCFFKPILFPFNEELLNKTKSSNDLVLYNIKLSHFKNLIYIYFQEKKIEGISLTINNECLIINYIKMVSKLLKKILQNLYNSDDIDIVYNFQHNTKNKCNYLSQNVNIPSDNTISNVIKKNEMDNNDIKYNLFTQREVKSSFFEFKYILFGFYDLFLMNQKNYTDLNEKKKEEYKKKNFINCFDSHSHYNFLNIIKEYINYDYIIDKCSYNISNDTQKKKKIKLNFYYFLLIIQYFKNTYTQEKKRSFFYMVYNELLQRDKYLKHFYYTYHEIDRKTNMHLNHNDNNIDTKEAKKNEETELILKNVNFYDNYELINIRKYDVILFCFLFHMYNFCLKQNGLSNDEFNSHITYFLINKKMKKYKKKYRYISKKKIDTNEKNDDNNNINVCDSKNYKGTKNFDDTTNNILNKQNESLDNLKKNMYLSKNNYDNQLSSYKNTKQNKTNINEKYNNNNIIMNYLTWKKCLYYIYKIKKYTRKIETHEGLYISSMLYINIYLCQIFFILLNILRINNTNIYTNIHFDIRKNNLDYFYLLILLNFYSLFYILISDQKYILHEEENDTYISKNIDNKEQMANDKNIISLLSFFNNIYEQNKEGMLKNDQNKNNHNTKTDILYMSSSGMNISINTPFLEKYLILIYNIIKDKINIVKEDNYIMEKLFFKINCMICNKVCVTNIYNNYYICENNHIFNKCMLTFGCIYKNHIILPTIYLLHDINDKLFPINNDHILSYNLQYELDYIYFCSFCYNFITTQNSFYKKFFLFNQCPFCNHELNIL
What are the official names of this protein?
Uncharacterized protein PF3D7_1223600.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS4Y1_MACFU
Sequence: MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRVDVTYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITAEEAKYKLCKVRKITVGTKGIPHLVTHDARTIRYPDPVIKVNDTVRIDLGSGKITSFIKFDTGNVCMVIGGANLGRVGVITNRERHPGSFDVVHVKDASGNSFATRISNIFVIGNGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG
What are the official names of this protein?
40S ribosomal protein S4, Y isoform 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: PRR7_RAT
Sequence: MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEERLREQNLRALELEPLELEGSLAGSPPGLAPPPPPHRSRLEAPVHAHSHVHVHPLLHHGPAQPHAHPHPHHHALPHPPPSHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAAPCPALCLQADRSRRVFPSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV
What is the function of this protein?
Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (PubMed:27458189).  Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (PubMed:27458189).  Might play a redundant role in the regulation of T cell receptor signaling (By similarity).  Might promote apoptosis in T cells (By similarity).
What are the official names of this protein?
Proline-rich protein 7, Synaptic proline-rich membrane protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Postsynaptic cell membrane; Single-pass type III membrane protein. Postsynaptic density membrane. Cytoplasm, perinuclear region. Synapse. Cell projection, dendrite. Nucleus. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities (PSD) (PubMed:15629447, PubMed:27458189). Accumulates in spines along with synapse maturation and colocalizes with DLG4 in a punctate pattern (PubMed:15629447). Translocates from synapses to nuclei following NMDA receptor activity (PubMed:27458189).
Protein: RLMN_CHLPB
Sequence: MPNSKTNIKAYTRQELRDTIAALGEPAYRADQIHRWLFSDWVTDFEKMKNISASLREELSRRYVIPSCSFENEAIEERSVSAPETSKFLVGLHDDEMVETVLIPSPDRHTVCVSSQVGCPLRCTFCATGYMGFTRNLLASEIVEQVLLVNERLGDRSPDNHVTNMVFMGMGEPLLNLNNVFDAIETLTNQSYNFSLSRKRITISTVGLIPQIGELARSGLSIKLAISLHAADQEKRTSLIPVAKEHTLEELRHALHEYADMVKEPVTLVYMLIEGVNDADQDAINLIRFAQGFLCKINLIDYNCIVNVKFNPVKAEKRDRFIHTLVNAGVHVTVRKSQGASIDAACGQLALQKKNKTASRPY
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_AZOSB
Sequence: MAKQQTKRAQASEERDDGLREKMVAINRVTKVVKGGRILGFAALTVVGDGDGGIGMGKGKSREVPVAVQKAMDEARRKMVKVSLKDGTLQHTVVGKHGAASVLMQPAPGGTGIIAGGPMRAVFEVMGVTDIICKCIGSTNPYNVVRATLNGLMAVNTPAEIAAKRGKTIEEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ISPE_CALS4
Sequence: MKLRIKAYAKVNLTLDVLSKREDGYHEILSVMQSIDLADVIEFEKAKEILFECDHERVPKGEENLIMKAFNAIRDRYFLNEGIKIKLFKNIPLAAGLAGGSADAAATIVALDKLWNLNLTEKEMEEIASEVGSDVPFCLKGGTKLASGRGEKLQDLEGIPLNLLLVKPDLEISTKEVYTEWDNSGFKSLNSTFLFVEALKKGDLLEIARNISNDLERVTSQKYRVIEDIKKSLIEKGALSASMTGSGPTVYGVFNDVEKLVRAYHDLKGVYPFVAISKTIDKGLEIL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: BIOC_ACIAD
Sequence: MFVNLNKSLIAQRFAKARQSYVENAIAQKKISHHLCHLMQAYCPLHLSRIFEIGCGSGNLTQELFVSFQIQRAYLNDLYDEVKQHFLDEQPIEWCIGDIESLSLPEHLNAIVSSSAIQWVQNLPQLLGRCHHALNDQGWLCLSTFGSDNFKEIKQLTGQGLSYWSVQDWQVHLQASGFELMKIEQQQLKMQFDSPRAILKHLKATGVTGTVATTQPHWNKQSLAQFYHDYCQFQTDDGHYELTYHPIYIIARRTS
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: HEM6_SALAR
Sequence: MKPDAQHVKQFLLRLQDDICQTLSAVDGANFIEDSWRREAGGGGRSRVLRNGGIFEQAGVNFSHVNGDAMPASATAHRPELVGRSFEAMGVSLVVHPRNPYIPTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTARDLCQPFGEDVYPRYKKWCDDYFFIKHRNEQRGIGGLFFDDLNTPDFASCFAFMQAVGKGYTEAYLPIVERRKTMAWGERERSFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKEGSPEAALSEFIQVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM87A_XENTR
Sequence: MAAASFQPLKCLLLWVFFVITPPVKAVPEPGIWTVPIGSGAGSLFFRKTLYNSTNIKVKLISPNCPTPVKLTVKWYLRSHRCYNQFTNLEEVLERHHTNLDTTDNFCKNVSKPDFCDKNEDKNIDCNKDMHALPTLKMSKLVPKISVNQSAGSKNPLNQMDFDIVARTYQDGPYLFVLQVKGDENVKWNLSVTVSMKGPHGFISASDWPLMIFYMVMCIMYILLALLWFIWSACYWKDLLRIQFWIAAVIFLGMLEKAVYYAEYQNTDNTGVSSHGLLIFAELISSIKRTLARLLVTIVSLGYGIIKPRLGAVMHRVVGMGVLYFVFAAVEGVMRIIGAKEYDLVLLAGIPLALLDSGLCWWIFVSLAQTMKTLKLRKNTVKYSLYRHFTNTLIFAILASIIFMIWRTKKFQLVDCQADWMELWVDDAYWRFLFFIILLVIMFLWRPSANNQRYAFTPLIDDSDDEVEEFLVTDHLAEGMKLRGTKPECNGAPKPPATNIDEDLKWVEENIPSSFADAALPVLMDSDEEIMMTKYEMSKIE
What is the function of this protein?
May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
What are the official names of this protein?
Transmembrane protein 87A.
What is the protein family that this protein belongs to?
Belongs to the LU7TM family. TMEM87 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: OBG_BART1
Sequence: MKFLDQAKVYIRSGNGGSGAVSFRREKFIEFGGPDGGNGGRGGDVWALVVDGLNTLIDYRYQQHFKAKTGGHGKGRNMTGEKGGDVILKVPVGTQIFEEDNTTLICDLTEVGQRYRLAKGGNGGFGNLHFTTSTNRAPRRANPGLAGEERAIWLRLKLIADAGLVGLPNAGKSTFLSSVTAAKPKVADYPFTTLHPHLGVVRIDGREFVLADIPGLIEGAHEGVGIGDRFLGHVERCRVLLHLISAQEEDVAKAYQIVRHELEAYGNNLSDKTEIVALSQIDTLTIEERKMKQKALRRVTDQPVMMFSAVSREGLENVLRAGAHIIEMSRKEEMGGDSRID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_RUEPO
Sequence: MRALIQRVSHASVTVDGVVVGQTGPGLLVLVCAMAGDGEAQADQLAAKIARLRIFKDEAGKMNRSVLDIGGAALVVSQFTLAADTRSGNRPGFSSAAPPAEGERIYEYFAAQLAAQGVPVETGRFGADMKVELLNDGPVTIWMDI
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O56A4_HUMAN
Sequence: MASPSNDSTAPVSEFLLICFPNFQSWQHWLSLPLSLLFLLAMGANTTLLITIQLEASLHQPLYYLLSLLSLLDIVLCLTVIPKVLAIFWFDLRSISFPACFLQMFIMNSFLTMESCTFMVMAYDRYVAICHPLRYPSIITDQFVARAVVFVIARNAFVSLPVPMLSARLRYCAGNIIKNCICSNLSVSKLSCDDITFNQLYQFVAGWTLLGSDLILIVISYSFILKVVLRIKAEGAVAKALSTCGSHFILILFFSTVLLVLVITNLARKRIPPDVPILLNILHHLIPPALNPIVYGVRTKEIKQGIQNLLKRL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 56A4, Olfactory receptor OR11-49.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEF99_ARATH
Sequence: MGSLKLSTVVVTALVVCLSILLISPTEAVEGKLKEECENVPYGFCPFWLFNPRSEELCKEKCKRFKSETSEYYGGFCTPNGPPGGVSLTATCNCCVREKVSPPEIEAVEGKLEVCDNLQIGMCLWYLWPWYDSTKRCEETCQKQNNSPSGARYRYYGGFCTPIVRGTGFFIHGACNCCIRDIKKQASS
What are the official names of this protein?
Defensin-like protein 99.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_VIBC3
Sequence: MNPLRVKLDALISKTSLTVTEQQREQLVGYVQLLDKWNKAYNLTSVRDPMEMLVKHILDSLVVSPHLVGERFIDVGSGPGLPGIPLAIMHPDKEFVLLDSLGKRIRFLKQVIHDLKINNVLPVQSRVEEFDPESGFDGVLSRAFASMTDMVNWCQHLPKPNAGVFLALKGVRPDDEITLLPEWCSVTDIKALQVPELEGERHLVILSRKG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_CLOK5
Sequence: MNRIDFKFKELKDQGKKALIPFITAGDPSLDTTVNIVLEMDKKGADIVEIGIPYSDPLADGPIIQGSSQRAIKGGAKIRNIMETVRKIRGKSEIPLVYMVYYSSIFKYGLERFIAEASAVGINGIIIPDLPIEERGDIMDITVKYEVHLIPLVAPTSKRRIQEIAAGGSGFVYCVSKNGVTGVGEKIKTDIKEYMELVGSYTELPKALGFGISGSSMAREFKPYCDGIIIGSAIIDIIYKCKGEKEILDKVGNFISEVKKSLE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: 3SA4B_NAJSP
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCNKLVPLFYKTCPAGKNLCYKMYMVAMPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 4b, Cardiotoxin-4b, CTX-4b, Ctx4b.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: SYK_CHLTR
Sequence: MSVEVEYLQHEDYLYRTSKLKEIRDLGINPYPYQYTDCLEVQEIRNQFVDNELGDSEAAFRKETPKVRFAGRLVLFRSMGKNSFGQILDNDAKIQVMFNRDFSAVAGLAADAGISPIKFIEKKLDLGDILGLEGYLFFTHSGELTVLVETVTLLCKSLISLPDKHAGLADKEIRYRKRWADLISSEDVRKTFLTRSRILKLIREYMDQQSFLEVETPILQTIYGGAEATPFVTTLQALHAEMFLRISLEIALKKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIEAYAAYWDYNDVMKCVENLVEYIVRALNNGETQVQYSHLKSGPQVVDFKAPWIRMTMKESISVYGGVDVDLHADHELRKILETQTSLPEKTYVHASRGELIALLFDELVCDKLIAPHHITDHPLETTPLCKTLRSGDETLVERFESFCLGKELCNAYSELNDPLQQRKLLEEQMRKKALNPDSEYHPIDEEFLEALCQGMPPAGGFGIGIDRLVMMLTDAASIRDVLFFPVMRRIEAKKD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMD_RAT
Sequence: MDDYAVLSDTELAAVLRQYNIPHGPILGSTRKLYEKKIFEYETQRRRLSPPSSSSSSFSYRFSDLDSASVDSDMYDLPKKEDALLYQSKDYNDDYYEESYLTTRTYGEPESVGMSKSFRRPGTSLVDADDTFHHQVRDDIFSSSEEEGKDRERPIYGRDSAYQSIAEYRPISNVSRSSLGLSYYPRSSTSSVSSSSSSPSSWLTRRAIRPEKQAPTAALGQDRQVPLWGQLLLFLAFATFLLFVYYSIQAQEGNPFWMDP
What is the function of this protein?
Stabilizes and promotes the formation of a nuclear actin cortical network.  Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments.  Inhibits beta-catenin activity by preventing its accumulation in the nucleus.  Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway.  Links centrosomes to the nuclear envelope via a microtubule association.  Required for proper localization of non-farnesylated prelamin-A/C.  Together with NEMP1, contributes to nuclear envelope stiffness in germ cells.
What are the official names of this protein?
Emerin.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass membrane protein; Nucleoplasmic side. Nucleus outer membrane. Note=Colocalized with BANF1 at the central region of the assembling nuclear rim, near spindle- attachment sites. The accumulation of different intermediates of prelamin-A/C (non-farnesylated or carboxymethylated farnesylated prelamin-A/C) in fibroblasts modify its localization in the nucleus (By similarity).
Protein: UBIE_NITMU
Sequence: MTRTTHFGFKTVSETEKAREVAGVFDSVAERYNLMNDLMSGGMHRLWKRFAIEVSGVRTGERVLDIAGGTADLSSLFLEQVGSRGEVWLTDINNSMLTIGRDRLLDEGTAVPVAQCDAEKLPFPTNYFDCVSVAFGLRNMTHKDVALKEMLRVLRPGGCVIVLEFSRIWKPLQRLYDLYSFKVLPAMGGLVAKDRDSYRYLAESIRVHPSQEELKQMMQKAGFERVQYFNLAANAVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.