PharMolix/UniProtQA huggingface dataset:
Protein: MED10_MOUSE
Sequence: MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLSQKLNFIVTGLQDIDKCRQQLHDITVPLEVFEYIDQGRNPQLYTKECLERALAKNEQVKGKIDTMKKFKSLLIQELSKVFPEDMAKYRSIRGEDHPPS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 10, Mediator complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y439_RICPR
Sequence: MQDFNIESRSVLHMTAQIRAKQLAIRDAQNREQEAIVKTWEENGIDKSDETVSNDIVNSLETFYNISKSLNDYLKTQGINDIGYPIKFNKTDLQLKMALNYAKQQEDNLIDQIIKGKFYNGLSNDINSQELPVLQSDNMLSFWGNENSSVSSVLLASVAQILNIEPVPLVGAATNYKLHNPEYTLPQELIPEDYRFASQKGMLVFGDYQYGGHRTFEEQLVFGPEDCSSSVGKATYLSNEQIKSITTTQMKENYSKYDYKLITLLKDIVEPKQLELIEAGDIYVYKGHCAVIATKPDNKAEITTLEFSRNIDRAENKISGGGIYNYSLIDKAQEEPLNPIYILRKNLEPLPSQSSLKYFLSAIDEKYLNLYPEGPNEDVVGDCRIFFETQE
What are the official names of this protein?
Uncharacterized protein RP439.
Protein: RL4_MARMM
Sequence: MKIEVKTLAAKDAGAIDLDDAVFGIEEVRSDLLQRVVKWQLAARQQGTHKTLGRSEINRTKKRFGRQKGGGTARHGARSAPQFVGGGKAHGPRVRSHAHELPKKVRALGLRHALSAKLGAKSLVIIDDAALDAPQTKALRTSFEGLGISNALVISGAEVNENFAKAARNLPCIDVLPAQGLNVYDVLRRDTLVLTKAAVEQIHARLSAKEA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: DRB3_ORYSJ
Sequence: MKKKSAPTPLPPETANTSPAPIGATAGIRVENCYVFKSRLQEYAQKAGLQTPEYHTSKEGPSHEPVFKSTVVINNTSYGSLPGFSNRKAAEQSAAEVALMEIVKSIPANANIPAVQETGLCKNLLQEYAQKMNYAIPSYICTKPASGLAPFLCTVEIGGIQYIGAAARTKKDAEIKAARTALLAIQGQSEGSANGATKYIVVPGKRVGKEVEKRPIETPKPLKAKKGGFKKKWNKRKFMKKDGQAVDVEKDEARVAGDAHDSDVLMQPTVITQEASCGTLFLQPCEEAKRVEDEPPRDIEMVQPDKENQHSDAALVQPDDEARVEQEPSRDISVVQPNEEAISAKQEPSIDAATLQPKEEAMKTGCVALVLCLNISVDPPDVIKISPCVRKECWIDPFSMAAPKALETIGKTLHSQYERWQPKARYKLQLDPTLEEV
What is the function of this protein?
Binds double-stranded RNA.
What are the official names of this protein?
Double-stranded RNA-binding protein 3, dsRNA-binding protein 3.
Protein: LIPA_HALSA
Sequence: MSSRRKPEWLKMRPPSGERFTDIKETLRDNDLHTVCEEASCPNMGECWSGRDGPGTATFMLMGDRCSRGCNFCDVKTGGMEPLDPDEPANVAESVAEIGLDYVVLTSVDRDDLDDQGAGHFARTIREIKERDPSILVEVLIPDFQGEKSLVQKIIDAGPDVIAHNIETVARRQVPVRDRRAGYEQSLSVLEYVTRESDIYTKTSIMLGVGEYDHEVYQTLGDLREAGVDVVTLGQYLQPSRSHLDVADYVHPQKFETWQRVAESEFGFLYCASGPMVRSSYKAGELFVDAVLREGKSVQEARRNARRAASE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_ECO7I
Sequence: MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATLERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDQTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKDERSSH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_AZOVD
Sequence: MAVERTLSIIKPDAVAKNVIGEILTRFEKAGLSVVAAKMVQLSEREAGGFYAEHKERPFFKDLVSFMTSGPVVVQVLEGEGAIAKNRELMGATDPKKAEPGTIRADFAVSIDENAVHGSDSEASAAREIAYFFAATEVCARIR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_RHIEC
Sequence: MTRTAKLTIIPPGKPLSGRAMPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRYMADALRAMGVAIDEPDDTTFVVTGSGRLTPPKAPLFLGNAGTATRFLTAAAALVDGTVIVDGDEHMRKRPIGPLVEAMRKLGIDVSAETGCPPVTVRGTGRFEADRILIDGGLSSQYVSALLMMAAGGDRPVDIELVGEDIGALGYIDLTTAAMKAFGAKVEKTSPVTWRVEPTGYRAADFVIEPDASAATYLWAAEVLSDGRIDLGVPNDAFTQPDAKAYETIAKFPHLPAEIDGSQMQDAVPTIAVLAAFNETPVRFVGIANLRVKECDRIRALSSGLNNIREGLAVEEGDDLIVHSDPALAGQTLPAEIDTFADHRIAMSFALAGLKIGGITILDPDCVGKTFPAYWRTLATLGVTYRDKD
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL8_ICTPU
Sequence: MGRVIRAQRKGAGSVFKAHVKHRKGAAKLRHIDFAERHGYIKGIVKDIIHDPGRGTPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVFCGKKAQLNIGNVLPVGVMPEGTIICCLEEKPGDRGKLARASGNYATVISHNPETKKSRVKLPSGAKKVISSTNRAVVGVVAGGGRIDKPILKAGRAYHKYKVKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDVPAGRKVGLIAARRTGRLRGTKTVQEKEN
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_MYCBP
Sequence: MRPALSDYQHVASGKVREIYRVDDEHLLLVASDRISAYDYVLDSTIPDKGRVLTAMSAFFFGLVDAPNHLAGPPDDPRIPDEVLGRALVVRRLEMLPVECVARGYLTGSGLLDYQATGKVCGIALPPGLVEASRFATPLFTPATKAALGDHDENISFDRVVEMVGALRANQLRDRTLQTYVQAADHALTRGIIIADTKFEFGIDRHGNLLLADEIFTPDSSRYWPADDYRAGVVQTSFDKQFVRSWLTGSESGWDRGSDRPPPPLPEHIVEATRARYINAYERISELKFDDWIGPGA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RECN_RICPR
Sequence: MFYSLSVKNFILIDELEIEFSKGLCVITGETGAGKSILLDAILFCLGYKTSNNIIKHGKDYTVVNIIFSLNEKIKKFLIQNFIEPEELLLVKCLQKAEGRKSFFINNQIVTKTLIKQLANYLFELHGQNNNITLLEASTQRDILDSYGDLLEFRVKLAKCYQIWQNTRKEIEEITVKQNVIEQEIDYLNFVTEELTKLNIQIGEEETLTNIRQDLQNKNKDLQLIRDIIAQINNPEINISINRAEKLLARQRDNDRFKAIATSLEEAYNNLEVARQELSNLLDSFTYEEYNLEETEERLFLIKAISRKYNVPANELGIFLDKSLEKLVILKNKIANSHKLQAQEVLLQEQYYKLANDLSARRLIAAKHLEESLNQELKQLKMEKANFKIEIKTAIDPTASGNDDIVFKASTNPGMKAEEINKIASGGELSRFMLALKTSLFDKMIKPSIIFDEIDVGIGGEAADKVGDRLKKLSSVTQVIVITHQPQVAGKADLHIKIEKTQLEQETKIKVKALNLAERQRELARMISGKTITDASLKVAKELLYPVACPHDQK
What is the function of this protein?
May be involved in recombinational repair of damaged DNA.
What are the official names of this protein?
DNA repair protein RecN, Recombination protein N.
What is the protein family that this protein belongs to?
Belongs to the RecN family.
Protein: STS1_CANGA
Sequence: MSGQMFWGKKEDGKRKRSFQESYETPKVQKCVRKRRPALNVQGQPLPPQRSLEMMSKDQLMSVLMEVMRQHPEVGSTFQAKVSSYQFASEKYQQLLKGKVEQLYSNIPYNRSYDNTNLDDYAFVRMKPYITELLNCLVDCALDNLPPRKSDLHESLKFLESCTQLVLDLPRFESGSNNYYYDKCLEQISHLWCSLIEQISKDIHMVMNTNMEEWITKLNAYNERSNGLLTSAVTLFKSLASDGDLLGDQQNEMESPAYVAGPGLLLESNPSYLMHNKYSM
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DAPE_CAUSK
Sequence: MTSPAPEPVSIDSVALAQALIRRPSVTPADEGAMDVLQRQLEALGFNCRRMKFGEIENLYARRGTERPNLCFAGHTDVVPVGDSAAWTQGPFEAEIQDGMLYGRGAVDMKSAIAAFVAAVSNLPRDLPGSLSFLITGDEEGVAEDGTVRVVQALAAEGEVIDHCIVGEPTSANLLGDMVKIGRRGSINAWIAVDGRQGHVAYPQRAANPIPVMVDILSRLQSRVLDEGYEGFQPSNLEVTTIDVGNTATNVIPASAKARINIRFNPAHQGKDLRAWIEQECRDAADGFSGRVEALCKIGGEAFLTQPGAFTDVIVAAVGDATGRVPELSTTGGTSDARFIRSLCPVVEFGLVGATMHAVDERVPVQEIRDLANIYQALIGRYFAAFA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: LDH_MYCGE
Sequence: MKGPKIAIVGSGAVGTSFLYAAMTRALGSEYMIIDINEKAKVGNVFDLQDASSSCPNFGKVVAGEYSQLKDYDFIFISAGRPQKQGGETRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPVDIMSYTYLKVTGFEPNKVIGSGTLLDSARLRYAIATKYQMSSKDVQAYVIGEHGDSSVSIISSAKIAGLSLKHFSKASDIEKEFGEIDQFIRRRAYEIIERKGATFYGIGEASADVAEQILKDTKEVRVVAPLLTGQYGAKDMMFGTPCVLSRKGIEKILEIELSNTEKVALENSIKVLKDNIKLAKL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_PELUB
Sequence: MKFKPLHDRVLIEVLDSSEKTAGGIIIPDTAQEKPQEGKVIAVGGGAKTEDGKLIPMDVKVGDKVLFGKWSGTEIKIDGKEYSIMKESDIMGISGK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHC_ECOK1
Sequence: MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEKTTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRQPLGIPAFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTPNAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALFSHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLGKPANVQVALDLDVKGFQQWVAEVLALAL
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: WECG_ECOSM
Sequence: MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAINAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMARAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASGAQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWLYRLLSQPSRIKRQLRLLRYLRWHYTGNL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: TRNH9_ARATH
Sequence: MVTRKMDKRLWSLQGMTALVTGAASGIGYAIVEELAGFGAKIHICDISKTLLNQSLSEWENKGFQVSGSVCDVTSHPEREKLMQTVSSIFDGKLNILVNNVGVLRGKPTTEYVADDFTFHISTNLEAAYHFCQLSHPLLKASGYGSIVFLSSVAGVVSLIDCGSIYGLTKGALNQLARNLACEWAKDGIRANAVAPNVVKTAQSQSFLEDVSKKEGLLSRTPLGRVGEPNEVSSLVVFLCLPAASYITGQTICVDGGLTVNGFSYQPHA
What are the official names of this protein?
Tropinone reductase homolog At2g29320.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily.
Protein: DXS_PSYCK
Sequence: MQQSPHSPQSQSLSASAVDSAVPLSKLQQTYAVIPRERPQTPLLDSVDSPADLKTFSSAELITLADELRLFVLYSAGQSGGHFGANLGVIELTIALHYLLDTPQDQIVWDVGHQAYAHKVLTGRRDQLGTIRSKTGLTAFPERAESVYDTFGVGHSSTSISAGLGMSLALRYQGRAQTVACIIGDGAMTGGMAFEAMNDAVQQDADLMVILNDNDMSISCSIGGFSRHLAMLWESGYQVDISDAGEPILCQRPDMQAFDRRKRHKEQRDVPQLEDNLFKAIGFTYFGPFDGHNIPELLRVLSLAKQVKGPVLVHIYTTKGKGFAPAELDPVGYHAISSLPAEDNAPKTEKAAIKPSLKYSQVFGQFLCDKAAQDKKLLAITPAMEEGSGMIEFARQFPERFFDVAIAEQHAVTLAGGMATQGVKPIVAIYSTFLQRGYDQLIHDVALQNLDVMFAIDRAGLVGEDGATHAGVFDFAFLRCVPNMLIAAPKDENECYHLLNTCYEYQGCTAVRYPRGVGTGATIIQPAQIYNIGEAVIESVLGTDDAPKKLALLAFGTMVETAQKAAEMIAKSPLLASSCQLHVVNMRWVKPLDTNLLETLVEQGVTHIATLEEHMIMGGAGSAVNEYLLNESAAFKIHRPTICNIGIPDRFVAHGSQAEQLADCGLDVEGVFNQLQNLLS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: NIA_LEPMC
Sequence: MSVTTQQPAVVPLPSSPRLPIESHAGPRSTQLPPSPPETVNGDDPKSITSTPAEPDFPLPPPANPKPQVLDIDKPTPDAHVPRDPRLIRLTGVHPFNTEPPLTDLYNEGFLTSPELFYVRNHGAVPEVQDEECLDWEFSIEGMVANPLKITLRQLLEEYENVTYPVTLVCAGNRRKEQNVVRKSKGFAWGAAGVSTALFTGVVMKDVIERAKPLRKAKYVCMEGADKLPNGYYGTSVKLNWVMDPNRGIMLAHKMNGENLSLDHGKPLRAVVPGQIGGRSVKWLKKLIVTAEPSDNWYHIYDNRVLPTMVDPDEAAKNPKWWMDERYAIYDLSPNSAIAFPAHEEKVVLASAENSYNVRGYAYSGGGRRITRCEVSLNKGKNWRLANIDYAEDKYRDFEGRELFGARLDMDWRETSFCWCFWNLDIATAELRDANDILVRAMDEAMCIQPRDMYWSVLGMMNNPWYRITIHHEGDVLRFEHPTQPALIPGGWMERVKKAGGNLTNGQWGEQIEGQELENTAVEEVKEIKMTKDGVNRIVELDELKWHESAEYPWFVVNDEVYDGTSFLEGHPGGAQSIISAAGLDASDEFMAIHSETAKAMMPAYHIGTLSPTASKQLSLEEPTSKQASSSSLRPTFLDSRTWSKALLSSKTKVSWDTRIFRFKLDHASQTLGLPTGQHLMIRLRDPVTREAIIRSYTPISQISEQGFCDVLIKIYADAPGREGGKMTKALDSIPCGHWVDMKGPIGKFEYLGKGVCSINGNERRVRSMKMICGGSGITPIYQVLRAILQDSADSTHCTVLNGNRLEEDILCREDLDRFAEENGERCTLVHTLTQAAEGWTGRRGRIGEELLKEFCGTEEDGLVLVCGPEGLERSVKGLLSGMAWRDDDVIFF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADPH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: MURF_RICPR
Sequence: MIWNSKTLSIALGIEISNSVNCNEVQFNSKDVKKGDLFIALQGNRDGHDYIQDAIDKGATAVIVSKQVEINDKDKIILVNNSFEALQKMALYKRENSKAKFIAITGSVGKTSTKEALKILLQHDFIVFASRGNFNNYLGLLINLASMADDTEYAIFELGMNHQGEISELVQILKPNIAMINNISEAHLEFFHSLEEIAEAKCEIFKNFSKNDIAIINASNNCYNKILSILKNLSITNIYSFGHSSKASAKLILYKTLGEQVHLQYYINNKFIDITIPFIPRHFANNYTGVLLIIDILGKDIEISAKYLADIALTKGRGKIINIQNSRVICDYYNASPQSMKAALEYLKQVPADNKTSIIGEMLELGWNSQRLHEELVPYILDAGCTKVYLVGAYTKYIYDLLPNKISKKFFKNVEELITHITDLFEYSELILIKGSRGVKLDKIVDYYQ
What is the function of this protein?
Involved in cell wall formation.  Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
What are the official names of this protein?
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase, D-alanyl-D-alanine-adding enzyme, UDP-MurNAc-pentapeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_RHOE4
Sequence: MKKQMHPDYHPVVFQDASTGKSFLTRSTVTSERTVEWEDGGTYPLLVVDVTSDSHPFWTGAQRVMDTAGRVEKFERRYGKRKAL
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: ALKB3_MOUSE
Sequence: MEDKRQRARVQGGWATPTKSQSATQPASPARSRLSQTAGPAWRSKEQQQCDRQFVFKEPQLVVRAAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDLKEADWILEQLCKDVPWKQRMGIREDVTYPQPRLTAWYGELPYTYSRITMEPNPHWLPVLWTLKSRIEENTSHTFNSLLCNFYRDEKDSVDWHSDDEPSLGSCPVIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSRQPRVNLTFRTVYPDPRGAPR
What is the function of this protein?
Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A) (By similarity).  Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation (PubMed:16174769).  Has a strong preference for single-stranded DNA (PubMed:16174769).  Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3.  Can repair exocyclic 3,N4-ethenocytosine adducs in single-stranded DNA.  Also acts on RNA.  Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons.  Requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, Alkylated DNA repair protein alkB homolog 3, mAbh3.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with ASCC2 and ASCC3 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage. Predominantly localizes to the nucleus.
Protein: RL4_NEIG1
Sequence: MELKVIDAKGQVSGSLSVSDALFAREYNEALVHQLVNAYLANARSGNRAQKTRAEVKHSTKKPWRQKGTGRARSGMTSSPLWRKGGRAFPNKPDENFTQKVNRKMYRAGMATILSQLARDERLFVIEALTAETPKTKVFAEQVKNLALEQVLFVTKRLDENVYLASRNLPNVLVLEAQQVDPYSLLRYKKVIITKDAVAQLEEQWV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: P4H11_ARATH
Sequence: MSKSTSVSTILYLRQRLQGLKIYETSDLIQHINTFDELVGEQVSVDVKIEEKTKDMILLCSLSPLLTTLTCSMVKVAASLRFPNERWLEVITKEPRAFVYHNFLALFFKICKTNEECDHLISLAKPSMARSKVRNALTGLGEESSSRTSSGTFIRSGHDKIVKEIEKRISEFTFIPQENGETLQVINYEVGQKFEPHFDGFQRIATVLMYLSDVDKGGETVFPEAKGIKSKKGVSVRPKKGDALLFWSMRPDGSRDPSSKHGKRHCLSLNLF
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences of plant glycoproteins and other proteins.  Hydroxyprolines are important constituent of many plant cell wall glycoproteins such as extensins, hydroxyproline-rich glycoproteins, lectins and arabinogalactan proteins.
What are the official names of this protein?
Probable prolyl 4-hydroxylase 11, AtP4H11.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: SSRA_BOVIN
Sequence: MSSLRRLLLLLLLVFPATLLLRVGPGGSLAVAQDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLAEDKEEDDVSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTIIEREDGLDGETIFMYMFLAGLGLLVVVGLHQLLESRKRKRPIQKVEMGTSSQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.  May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins (By similarity).
What are the official names of this protein?
Translocon-associated protein subunit alpha, TRAP-alpha, Signal sequence receptor subunit alpha, SSR-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAP-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RFOX1_MOUSE
Sequence: MNCEREQLRGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPDHTLNLYPPTQTHSEQSADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTESKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPDFYAGTVLLCQANQEGSSMYSGPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHTLAPAPTYGVGAMNAFAPLTDAKTRSHADDVGLVLSSLQASIYRGGYNRFAPY
What is the function of this protein?
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements.  Prevents binding of U2AF2 to the 3'-splice site.  Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.
What are the official names of this protein?
RNA binding protein fox-1 homolog 1, Ataxin-2-binding protein 1, Fox-1 homolog A.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Protein: TPIS_ECO57
Sequence: MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R10A2_ARATH
Sequence: MSKLQSEAVREAITTIKGKSEEKKRNFVETVELQIGLKNYDPQKDKRFSGSVKLPHIPRPKMKICMLGDAQHVEEAEKMGLSNMDVEALKKLNKNKKLVKKLAKSYHAFLASESVIKQIPRLLGPGLNKAGKFPTLVSHQESLEAKVNETKATVKFQLKKVLCMGVAVGNLSMEEKQLFQNVQMSVNFLVSLLKKNWQNVRCLYLKSTMGPPQRIF
What are the official names of this protein?
60S ribosomal protein L10a-2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.