PharMolix/UniProtQA huggingface dataset:
Protein: SUBB_ECOLX
Sequence: MTIKRFFVCAGIMGCLSLNPAMAEWTGDARDGMFSGVVITQFHTGQIDNKPYFCIEGKQSAGSSISACSMKNSSVWGASFSTLYNQALYFYTTGQPVRIYYKPGVWTYPPFVKALTSNALVGLSTCTTSTECFGPDRKKNS
What is the function of this protein?
Receptor-binding subunit of subtilase cytotoxin SubAB5.  Required for receptor-binding and thus correct trafficking in the host cell (PubMed:18042253, PubMed:17024087).  Has specificity for host glycans terminating in the sialic acid N-glycolyl-alpha-neuraminic acid (Neu5Gc); each subunit in the SubB pentamer binds one Neu5Gc (PubMed:18971931).  The protease subunit (SubA) cleaves host BiP/HSPA5, inducing the host endoplasmic reticulum stress response and eventual cell death (PubMed:18005237, PubMed:18433465).  Culture supernatant of E. coli expressing both subA and subB are toxic for Vero cells (African green monkey kidney cell line), Chinese hamster ovary cells and Hct-8 cells (human colonic epithelial cell line); the subunits are not toxic individually (PubMed:15226357).  Purified SubAB5 is highly toxic, <0. 1 pg is able to kill at least 50% of 30'000 Vero cells in a microtiter plate assay after 3 days; no cytotoxicity is seen at 24 hours (PubMed:15226357).  Preabsorption with cells expressing a ganglioside GM2 mimic reduced cytotoxicity of SubAB5 by 93% in the Vero cytotoxicity assay (PubMed:15226357).  Intraperitoneal injection of 200 ng of purified SubAB5 kills mice; the higher the dose the faster the mice die.  Animals injected with purified SubAB5 have microvascular thrombi in the brain and other organs, including the renal tubules and glomeruli.  Mice fed E. coli cells expressing cloned SubAB5 experience drastic weight loss and appear ill and lethargic (PubMed:15226357).  SubB alone at 2. 5 ug/ml causes vacuolation of Vero cells, which requires the V-type ATPase proton pump; treated cells die (PubMed:17101670).  Protein synthesis in Vero cells is transiently inhibited by SubAB5; both subunits are required for this effect (PubMed:17101670, PubMed:18005237, PubMed:18433465).  Inhibition of protein synthesis is prevented by brefeldin A; cells are arrested in the G1 phase (PubMed:18005237).  SubAB5 at 100 ng/ml induced caspase-dependent apoptosis in Vero cells through mitochondrial membrane damage (PubMed:19380466).
What are the official names of this protein?
Subtilase cytotoxin subunit B.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm, host cytosol. Host endoplasmic reticulum lumen. Note=Colocalizes with host BiP/HSPA5 in the endoplasmic reticulum of Vero cells, its activity on BiP/HSPA5 is blocked by pretreatment with brefeldin A, which disrupts the Golgi apparatus and inhibits retrograde transport from the cell surface to the Golgi (PubMed:17024087, PubMed:18005237). Using different inhibitors it has been shown to be actively internalized by membrane- bound vesicles and undergoes clathrin-dependent retrograde transport, via early endosomes and the Golgi network, to the endoplasmic reticulum (PubMed:18042253). Trafficking is similar in Vero cells, human HeLa cells and murine N2A cells (PubMed:18042253).
Protein: ISPG_NAUPA
Sequence: MIKRYPTRKIKVGNVDVGGDAPISVQSMTYSKTKDIESTLDQINRLYFAGADIVRVAVLDEEDALALKEIKQKSPLPVIADIHFNYRLGLKAAEVVDGLRINPGNIGGKERVKAIVDACKARKIPIRIGVNAGSLEDHLENKYGQTPKAMVESALWHIKFLEDLDFFDIKVSLKASDVQRTVEAYRMLRPLVDYPFHLGVTEAGTKFHATIKSAAAFGALLLDGIGDTMRVSITGELEEEIKVGKAILKDLGLSKEGVNIISCPTCGRIEVDLPPIVEAVEEATKHIKKPLNLAVMGCVVNAIGEAKEADVAIACGKGYGLIIKKGEIIGKYKEEELLEKFLEEVKKESE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: HIS3_STRMU
Sequence: MTDLSLDFKKQGGLLPVIVTDFQTGQVLMLAYMNEEAYQKTLDSKEMYYWSRSRNELWHKGDTSGHYQYVKSIKTDCDQDTLLIAVEQVGAACHTGAYSCFFNEIYNPE
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DING_STAA8
Sequence: MGMATYAVVDLETTGNQLDFDDIIQIGITFVRNNQIIDTYHSMIRTNLEIPPFIQALTSIEENMLQQAPYFNQVAQEIYDKIKDCIFVAHNVDFDLNFIKKAFKDCNIQYRPKKVIDTLEIFKIAFPTDKSYQLSELAEAHGITLANAHRADEDAATTAKLMILAFEKFEKLPLDTLKQLYYLSKQLKYDLYDIFFEMVRQYDAKPLDKSYEKFEQIIYRKQVDFKKPTTNYNGSLKSLYSKAVDQLGLTYRPQQLYLAETILDQLMHSEKAMIEASLGSGKSLAYLLAALMYNIETGKHVMISTNTKLLQSQLLEKDIPAMNEALNFKINALLIKSKSDYISLGLISQILKDDTSNYEVNILKMQLLIWITETPSGDIQELNLKGGQKMYFDQKIETYVPARHDVHYYNFIKRNAQNIQIGITNHAHLIHSDVENSIYQLFDDCIVDEAHRLPDYALNQVTNELSYADIKYQLGLIGKNENEKLLKAIDQLEKQRILEKLDIAPIDIFGLKASMNEIHELNEQLFSTIFTIINDSDVYDDDIHRFHNVFTFETKDILKDLHAIIDKLNKTLEIFNGISHKTVKSLRKQLLYLKDKFKNIEQSLKAGHTSFISIKNLSQKSTIRLYVKDYAVKDVLTKQVLEKFKSLIFISGTLKFNHSFEAFKQLFNKDVHFNTFEVNTSLQSAKNTSVFIPSDVASYQYKNIDEYVASIVSYIIEYTTITSSKCLVLFTSYKMMHMVQDMLNELPEFEDYVVLTQQQNQNYKIVQQFNNFDKAILLGTSTFFEGFDFQANGIKCVMIAKLPFMNKHNAKYWLMDSEFTSTFKEYVLPDAVTRFRQGLGRLIRNENDRGIIVSFDDRLINSNYKNFFEQTLENYRQKKGDIQQFGKLLRQIQKKKK
What is the function of this protein?
3'-5' exonuclease.
What are the official names of this protein?
3'-5' exonuclease DinG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.
Protein: CHEB2_CERSP
Sequence: MKAAADRLMAARAREGRTRVLIVDDSAMVRQALALGLSTDPRLEVVGTASGAEAARAQMAALKPDVVTLDLEMPQMDGLTFLRSYMESAPVPTVVISSLTRTSGETAMRAMEAGAVDIISKPSLGAGQGLPAIMRDVCARVWAAARARLALPDGAAPAPVAPGASEDWIHALGASTGGVQALSRILPFFPAQSPGLLVVQHMPEGFTAAFARRLDALCRMRVREAADGDLVLPGLVLIAPGGLRHMEIERAGGVCRVRLVAGAPVSYSRPSVDRMFLSLAAAAGPRVSAALLTGMGRDGAAGLLAIRRAGGRTFAQDEGSSAVFGMPLAARDLRAAEEILTLDDIPARMMLAAAADTRAPSLASND
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase of group 2 operon.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJB_SCHPO
Sequence: MQYYQMMKALRMLKKPKPGCLGIEIQSVPIPQPKNGELLVKIEAAAINPSDLMNATGGFPYTVYPRIVGRDYAGTVISGASHLVGTRVFGTSGSELSFTKDGTHAEYCIIPEKAAVRMPSNLSFTEAASVGVPFTTAYLALSRGETKGSDIVLVVGALGAVGSAVCQIAEDWGCKVITVSRSGSTDINTVVDPELKRVHELVEKVDVVIDTVGDPLLMKSALNQLGIGGRLSYISAPKQGSIEFSYDMKQIYRKNLKIIGCNSLLLSLVESNSLLKNMVAKFEAGKYKVLNKKIAETSLTDECINSYRKLMNECSTKFVITMSTN
What are the official names of this protein?
Zinc-type alcohol dehydrogenase-like protein C337.11.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YDJC_LISMH
Sequence: MKIIFNADDFGISPGAVYGILESYKRGVVKSTTLLANSPAFDLAVEVAKENPGLDIGAHLTLTFGSPVLQGLETLTDDDGRFRRNYTALENGLADVDMNEVERELTAQIEKILDAGITISHFDTHHSIEPLIYPVQHKLAEKYGVSIRRHSDVSDFGAIKTPDLFATEFYADGVSFETIKKLVQEHIGTNDVVEVMTHPAYIDETLREISSYVEPRIKEVSILTSRELQAYLGQQEVEIISFRDL
What is the function of this protein?
Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
What are the official names of this protein?
Carbohydrate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family.
Protein: LIM7_CAEEL
Sequence: MNICMRNGYEQFSLTSPGTSDLEIGGSFWKDEPDTKYLCLDSPVEQRQHQPPMAVCAGCRLEISDRYFLRVNPNLEFHAQCLKCVQCSRPLDENQTAFVKNGQTYCRDDYRRLFTTRCSRCHGDFDKTDLVMRAGPQNVFHLNCFACVACEKRLQTGEEFQIKNNSLYCRSDCRGLDNPDTSASVPDYSKLNNNNNNDNNNSSSNFDEDEWDEERSTLTSLDNNTSSPLGSPKSDGVRTPLFGHHNSGSGGSTSSCGKKKKDKQATRVRTVLNENQLKILRDCYSINSRPDATLKERLVEMTGLSARVIRVWFQNKRCKDKKRQIQITENRLNSEREEVLNRVRVNGIGPLMVQPATPHIDNTLGGPIDIQHFAQWNGTPPPPPPQYGNPMMFNSPSTFDVSVILAPVAPNVTSPSEALGPLGASVFPHFSPQHAPFTATSHDISSPAPCGE
What is the function of this protein?
Probable DNA-binding transcriptional activator.
What are the official names of this protein?
LIM/homeobox protein lim-7.
What are the subcellular locations of this protein?
Nucleus.
Protein: IHFA_LEGPH
Sequence: MIVNALSKAIMAETLCDELKLNKPVAKEMVENFFEELRHALENGQHVKLSGFGNFTLRDKPQRPGRNPKTGEEIPVEARRVVTFKPGLKLKTKIEKIGK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PCBD_PROMA
Sequence: MQTYGNPEVTYGWWAGNSVVTNRSGRFIASHVGHTGLICFAAGGSTLWELARYNPEIPMGHQSSLFLAHLASIGIGFDEAGAWTGVGVATIAIVHLILSMVYGGGGLLHGILFDENVEDSEVLQAKKFKLEWNNPDNQTFILGHHLIFMGVACAWFVEWARIHGIYDPALGAIRQVNYNLDLSMIWQRQFDFITIDSLEDVMGGHAFLAFAEITGGAFHIVAGSTPWEDKKLGEWSKFKGSELLSAEAVLSWSLAGIGWMAIVAAFWCASNTTVYPEAWYGEPLQFKFAISPYWVDTGDLSDATAFWGHSARAALTNVHYYLGFFFLQGHFWHALRALGFNFKNVTASIGNEQKATFTIKS
What is the function of this protein?
The antenna complex functions as a light receptor, it captures and delivers excitation energy to photosystems II and I.  The Prochlorales pcb genes are not related to higher plant LHCs.
What are the official names of this protein?
Divinyl chlorophyll a/b light-harvesting protein PcbD.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. IsiA/Pcb subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: HEM1_VIBCH
Sequence: MSLLAIGINHNTASVELREKVAFGPEKLSLALNQLSTSSHVKGGVILSTCNRTEIYCDVRSASKNKVIEWLSQFHQVSLDELKPSLYVHEEQAAIRHLMRVACGLDSLVLGEPQILGQVKQAYAEARENHAVNPATEKLFQKAFSVAKRVRTETEIGGSAVSVAYAACTLAKHIFESLADATVLLVGAGETIELVAKHLAGHHCKRMIVANRTRERALSLAQQFGADVIALNEIPDYLAQADIVISSTASPLPIIGKGMVESALKARRHQPMLLVDIAVPRDIEPQVGKLNDAYLYSVDDLQSIVDSNIEQRKVEAIQAEAIVSEESATFMSWMRSLQAVDSIRDYRKQANEAREELLNKSLQALAAGGDPEKLLIELSNKLTNKLIHTPTRALQTAAEQGEPAKLAVIRQSLGLDDLN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: Y270_BARQU
Sequence: MGIIKFDKVTQVFGDLCVLRDITVQLTEKRIAVIGANGSGKSTFVRLINGLQLPSNGFVSVDGLDTKRDAKAVKRKVGFVFQNPDNQIVLPLVEEDLSFGLKNLNLSKDEIKKRVDEILQRYDLQAFKNHAVHLLSGGQKQLVAISSVVAMKPDYIVFDEPTTLLDLRNKRRVTQVIEELPQTAIVVSHDLEFLKNFDRILVFDKGEIAIDDVPLVAIKEYIRRMS
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein BQ02700.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LNK2_ARATH
Sequence: MFDWEEEELTNMIWGDDAETGDHIVPFKVRSEQLNKKEQIEESKTAEQKITGTKIDLHDKNLGSSSSHNVDEGLPQPDFCMSSWPDTSLTNATKVDQDLSATELSKCLAEPVRYDSTRGGAFLLKQSCFTWVRSFQSNHFKSCVLTLFLPEKTSELGKGPDIFHSSDESKEQGDFDDYSWANIGSFDDLDRMFSDGFAAMMSLYLVMAVSAVVMSYGHLLKITEFEQQENQQFPLTGKANGLSSQSVPSVRVTLKADQYREHKGQPSVEDQPYQQNKMMKFSKMPGTSEARPFQELYGQRIPFSNSAGKCVNQLAPPQSSLMAVNLLSESEGSGTSHYSHMPNQYMANSAFGNLANPYSSVPVISAVQHPDVRNQLMHPSYNPATATSVNMATDASARPSTMTPQEKLEKLRRRQQMQAMLAIQRQQQQFSHQVPVADQSITQNCLQDIPLQLVDKTNLQGLTAMPSFDPSSSLEQDDSGKFAAAVDNSAEFAVLYRLQDVVAKLDMGTRTCIRDSLFRLAGSAAQRHYTSDTSHSNKTSQDDQEVIPREESRYRYAGMPDTEAVTNPTDRTVAHLLFHRPFDMLAAKRMEGPESPASSKMGTEEKGNFPKCSIRETHLTKQKAQKEEGPADSLALGNAPNSGSSSTVGERVVEASQGNKRKL
What is the function of this protein?
Transcriptional coactivator necessary for expression of the clock genes PRR5 and TOC1 (PubMed:25012192, PubMed:25848708).  Antagonizes REV8 function in the regulation of anthocyanin accumulation (PubMed:25848001).  Involved in red light input to the clock (PubMed:25012192).  Activates clock-controlled genes with afternoon peak (PubMed:23818596).  Mediates light inhibition of hypocotyl elongation (PubMed:23818596).  Unable to bind to DNA, but recruited to the evening element (EE)-containing region of the PRR5 and TOC1 promoters through its interaction with the DNA binding proteins REV8 and REV4 (PubMed:25012192, PubMed:25848708).
What are the official names of this protein?
Protein LNK2, Night light-inducible and clock-regulated 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEMH_CUPPJ
Sequence: MTFSPEPAYQHGQAPRTAILLVNLGTPDAPTPKAVGRYLKEFLSDPRVVEIPRLAWLPLLYGVILPLRARASALKYESIWLREAHMTGSPLLVYSERQAHALQRLLNQQGYELTVACAMRYGNPSIASVLEALRRQGTEQVLVLPMYPQYSGTTTATAFDEVFRVLGQWRNQPEIRLVKHFHDHPAYIAALHQQVGAYWAQHGTPDFARGDKLILSFHGVPRRTLELGDPYHCECLKTGRLLGDALGLQPGQYQVTFQSRFGKAEWLQPYTAPTLAELGKVGAGRVDVFCPGFPADCIETLEEIAMEGQTEFMVAGGKTFHFIPCMNDAQPWISALAEIALQHVQGWPLNMPHAHELEARRSRAQTRGAAA
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODA_SINFN
Sequence: MRPQMRWKLCWENELELSDHTELAEFFRKTYGPTGTFNARPFEGGHSWAGARPELRVIGYDAHGVAAHMGLLRRFIRVGDADLLVAELGLWGVRPDLEGLGLNHSIRVMYPVLQQLGVPFAFGAVRHALYKLVGRLCRNGLGTIVAGVRVRSTLSDVYLNLPPTRTEDVLVVVFPIGRPMSEWPSGTLIERNGPEL
What is the function of this protein?
N-acyltransferase required for nodulation.  Acts in the production of a small, heat-stable compound (Nod) that stimulates mitosis in various plant protoplasts.
What are the official names of this protein?
Nodulation protein A.
What is the protein family that this protein belongs to?
Belongs to the NodA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y088_MYCBO
Sequence: MSNANFSILVDFAAGGLVLASVLIVWRRDLRAIVRLLAWQGAALAAIPLLRGIRDNDRALIAVGIAVLALRALVLPWLLARAVGAEAAAQREATPLVNTASSLLITAGLTLTAFAITQPVVNLEPGVTINAVPAAFAVVLIALFVMTTRLHAVSQAAGFLMLDNGIAATAFLLTAGVPLIVELGASLDVLFAVIVIGVLTGRLRRIFGDADLDKLRELRD
What are the official names of this protein?
Uncharacterized protein Mb0088.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y780_BACAH
Sequence: MNIWLSMLTTTGLGAIIGGFTNHLAIKMLFRPHRPMYIGKFQVPFTPGLIPKRRDELAVQLGKMVVEHLLTPEGIGKKLTNEEFQKGLIHWAQVEVDKVMTNEQSLRHMLEKWDVAHVEKEATEKIEQVIIEKIEAFLEEYYTYTWEQALPHSVHEKIENAIPNVSAFILKRATHFFESEEGKSRLSKMIDDFFASRGALLNLVGMFLGNVSVVDRVQPEVIKFLGQDGTKQLLTDVLQKEWEKLKGRDVKELETFVEKEMIASSILSAVQVEETVGKFLNQSVQQVCEPVRETIIEKVVPGAVTKGLEWGAKNVESILNNLHLAEIVQQEVSTFSTERLEDLVLSITKNELKMITYLGALLGGMIGIVQGLLLLFLK
What are the official names of this protein?
UPF0754 membrane protein BALH_0780.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSCL_LIMF3
Sequence: MLKEFKEFIARGNVMDLAVGVIIGAAFTAIVKSLVSNLINPLIGIFLGKIDLSNLVFSIGSAHFRYGSFLNEVINFLIIAFVVFLMVKGINKVMPKKEEEAVKEGPSKEEEYLGQIVELLKKQDK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HMAT_HALSA
Sequence: MSNDNDTLVTADVRNGIDGHALADRIGLDEAEIAWRLSFTGIDDDTMAALAAEQPLFEATADALVTDFYDHLESYERTQDLFANSTKTVEQLKETQAEYLLGLGRGEYDTEYAAQRARIGKIHDVLGLGPDVYLGAYTRYYTGLLDALADDVVADRGEEAAAAVDELVARFLPMLKLLTFDQQIAMDTYIDSYAQRLHDEIDSRQELANAVASDVEAPLSSLEATSQDVAERTDTMRAATDDQVDRMADVSREISSVSASVEEVASTADDVRRTSEDAEALAQQGEAAADDALATMTDIDEATDGVTAGVEQLRERAADVESVTGVIDDIAEQTNMLALNASIEAARAGEAGEGFAVVADEVKALAEESREQSTRVEELVEQMQAETEETVDQLDEVNQRIGEGVERVEEAMETLQEITDAVEDAASGMQEVSTATDEQAVSTEEVAEMVDDVDDRAGEIAAALDDIADATDQQVRTVEEVRETVGKLS
What is the function of this protein?
Heme-containing signal transducer responsible for aerotaxis, the migratory response toward or away from oxygen.
What are the official names of this protein?
Heme-based aerotactic transducer HemAT.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
Protein: FETP_ESCF3
Sequence: MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: NDHO_GLOVI
Sequence: MPIKKGSLVRAVRDKLDNSLEALANDTRWPSYLFETDGEVLDMRGDYALIKFGAVPTPPVWLRQDQLAESGAAAESTS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LEXA_YERP3
Sequence: MKALTTRQQEVYDLVRDHLAQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLMEEEEGLPLIGRVAAGEPLLAQQHIEGHYKVDPSLFKPGADFLLRVNGMSMRDIGILDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNIVHLLPENSEFQPIVVDLREQSFTIEGLAVGVIRNGDWI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RK2_ANGEV
Sequence: MAIRLYRAYTPGTRNRSVLGFEELVRIKPRKKLTSGQHSGKGRNNRGIITSRHRGGGHKRLYRRMDFRRNKIDVPGRIDSIEYDPNRNTYICLVNYEDGEKRYILHPRGIKIGDMIVSGSEAPISRGNALPLSKMPLGTTIHNVEITPGKGGQLARAAGAVAKLIAKEGRLATLRSPSGEVRLISQDCLATVGQIGNADINNKNFGKAGSKRWLGKRPKVRGVVMNPVDHPHGGGEGRAPIGREKPLTPWGYTAFGRRSRKIRKYSNIFILRRRRRN
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL21_NOCFA
Sequence: MATYAIVKTGGKQYKVAVGDLVKVEKIEGEPGAAVELSPVLVVDGAELTTEAEALAKRSVTAELVEQTKGPKIRIHKFKNKTGYHKRQGHRQPLTVLKVTGIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CHST3_CHICK
Sequence: MERRSALPQDFREVLHCLKMRSKYAVLLVFVVGLVIIEKENNFISRVSDKLKQSPQVLPEANETEASPVQAENGSLASLRQLDTAFSQLRTRLRNVTLQLAGELGIAAPEPRRHVLLMATTRTGSSFVGEFFNQQGNIFYLFEPLWHIERTVTFEPGGANAVGSALVYRDVLQQLLLCDLYILESFISPAPEEHLTAALFRRGSSHSLCEEPVCTPSLKKVFEKYHCKNRRCGPLNITLAAEACRRKQHMALKTVRIRQLEFLQPLAEDPRLDLRIIQLVRDPRAVLVSRMVAFSGKYESWKKWAAEGEAPLQEDEVQRLRGNCESIRLSAELGLRQPRWLRGRYMLVRYEDVARAPLRKALEMYRFAGIHPTPQVEEWIRANTQAPQDSNGIYSTQKNSSEQFEKWRFSIPFKLAQVVQDACEPAMRLFGYKLASSAQELTNRSLSLLEEGPPTRIT
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin (PubMed:7629189).  Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices (PubMed:7629189).  Catalyzes with a lower efficiency the sulfation of Gal residues of keratan sulfate, another glycosaminoglycan (PubMed:7629189).  Can also catalyze the sulfation of the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides (PubMed:9147050).
What are the official names of this protein?
Carbohydrate sulfotransferase 3, Chondroitin 6-O-sulfotransferase 1, C6ST-1, Chondroitin 6-sulfotransferase, C6ST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: LEU1_MARMS
Sequence: MLTQPSIKYRPAQIIDFPARTWPSKQLKTPPRWCSTDLRDGNQALANPMDHVKKMAFFKHLIECGFKEIEVAFPAASQTDFDFVRLLIEGKHIPDDVTIQVMTQSRVDLIERTIQSLVGAKKAIVHIYNATAPVFREIVFCQDKPATLELAVQGVKHIRQLCEQYPDTQWTLQYSPETFCFTEPDFALEVCEAAAKTWQPSLERPMILNLPTTVEVNTPNVFADQIEHFITSFSSLENITISVHPHNDRGTGVATAEMAILAGAQRVEGCLFGNGERTGNVDLVTLAMNLYSQGVYPNLDFSDMRRTVELVEECNELPVHPRHPYAGALAFTAFSGSHQDAIKKGFASQKSTSSMIWQIPYLPLDPKDIGCTYEEVIRVNSQSGKSGAAWLLQENHGLFLPRKLQIDFSKKVKNHTDQTGHEMPLADVWRLFRESYRLNPDDKGQMKLMDYRSHSSNGLQEIRATLRYQEKTWQLVGEGKGLLSAMLDALRKRFNWQINISDFHEHTLGQQTKSKAVSYVQIESDQATPSFGVAIDEDSTKASLQALINACHPLYKEA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.