PharMolix/UniProtQA huggingface dataset:
Protein: ACSA_XANCP
Sequence: MADVYPVDPAFAADARITREQYATLYRESIEHPEQFWGKAAQRLDWFKQPTQIKDVSFALDDFHVRWFGDGELNASVNCLDRQLATRGDKTALLFEPDSPDSPSYPVTYRELYERVCKLGNALRNLGVKKGDRVTIYLPMIVDAAVAMLACARIGAVHSVVFGGFAANSIADRVIDCQSKLIITADEGLRGGKKIPLKANVDAALKIPGTNTVETVLVVRHTGGAVDMQAPRDRWFHDVVDGQPAECEPERMNAEDPLFILYTSGSTGKPKGVLHTTAGYLLFASYTHEVVFDLREDDIYWCTADVGWVTGHSYIVYGPLANGATAVMFEGVPNYPNVSRFWEVIDKHQVTIFYTAPTAIRALMREGEAPVKKTSRSSLRLLGSVGEPINPEAWRWYYEVVGDSRCPIVDTWWQTETGGILISPLAGAVDLKPGSATLPFFGVQPALVDAEGKILEGATEGNLVLLDSWPGQMRTVYGDHQRFIDTYFRTYPGSYFTGDGCRRDADGYYWITGRVDDVINVSGHRIGTAEVESALVSHPKVAEAAVVGFPHDVKGQGIYAYVTLIAGETPSEELHKELVSWVRKEIGPIASPDHLQWAPGLPKTRSGKIMRRILRKIAENAPDQLGDTSTLADPSVVDSLVNERLTR
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL6_NATTJ
Sequence: MSRIGKKPIEIPDSVDISINNNEVTVKGPKGELSQVVDQSIILEEEEGQLLVKRPTDSNHHKSLHGLSRSLIANMVEGVTNGFERHLEIVGVGYRAQMQGKNLVLNVGYSHPVTIEPPEGVEIEVPKNNQIIVKGTDKEVVGQVAARIRAVRKPEPYKGKGIKYAEEQIIRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SCPB_BACC3
Sequence: MDRTEQKSIIEGLLFVSGDEGIYPEQIAKVLEIEGNEVIDILEEMQKECEGAHRGLQIVQYAKVYRFATKKEHASYYQKLIEIPTAASLSQAALETLAIVAYRQPITRTEMEEIRGVKTDKALQTLVSHLLIKEMGRAEGPGRPILYGTTKEFLDTFGLKTLDDLPPLSEENEQMNEADLFFGSLQEISK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: ACCA_XANOP
Sequence: MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYINTICDEFQELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDTPGAYPGIGAEERGQSEAIARNLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAGKAKDAAEQLGLTARRLKDLSLVDKVIREPTGGAHRNPQQMGKRLKAVLLNELDALEKVPLETLLQQRYERLRSYGAYEGR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_ECO45
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITDDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: XGPT_YERPN
Sequence: MNEKYVVTWDMLQIHARKLAQRLLPAEQWKGIIAVSRGGLVPAGILARELGIRYVDTVCISSYDHDNQRDLKVLKRAEGDGEGFIVIDDLVDTGGTATAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMAVTFVAPLSGK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CRCB_PROM5
Sequence: MNKIFFFKILLFAYLASFLRFFLNNNLLVGVIGSFVYGFVISRRVSKLKKEILLTGFCSCFTSFSGFVLFLYEISIQGYFLKLFFYLNIIIVLNLIIMYAGFLLGRKVT
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COX4_MYCTO
Sequence: MHIEARLFEFVAAFFVVTAVLYGVLTSMFATGGVEWAGTTALALTGGMALIVATFFRFVARRLDSRPEDYEGAEISDGAGELGFFSPHSWWPIMVALSGSVAAVGIALWLPWLIAAGVAFILASAAGLVFEYYVGPEKH
What is the function of this protein?
Part of cytochrome c oxidase, its function is unknown.
What are the official names of this protein?
Probable cytochrome c oxidase polypeptide 4, Cytochrome aa3 subunit 4, Cytochrome c oxidase polypeptide IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DHQS_ACTCC
Sequence: MAAFSLSAKQILSPSTHRPSLSKTTTADSSLRFRNPHSLSLRCSSLSSSSNVGRTRLMRASASSTAPVMDTSPTKAVSSAPTIVDVDLGDRSYPIYIGSGLLDQPDLLQRHVHGKRVLVVTNSTVAPIYLDKVVGALTNGNPNVSVESVILPDGEKYKNMDTLMKVFDKAIESRLDRRCTFVALGGGVIGDMCGYAAASFLRGVNFIQIPTTVMAQVDSSVGGKTGINHRLGKNLIGAFYQPQCVLIDTDTLNTLPDRELASGLAEVVKYGLIRDANFFEWQEKNMPALMARDPSALAYAIKRSCENKAEVVSLDEKESGLRATLNLGHTFGHAIETGFGYGQWLHGEAVAAGMVMAVDMSYRLGWIDESIVNRAHNILQQAKLPTAPPETMTVEMFKSVMAVDKKVADGLLRLILLKGPLGNCVFTGDYDRKALDETLHAFCKS
What is the function of this protein?
Catalyzes the second step in the shikimate pathway.
What are the official names of this protein?
3-dehydroquinate synthase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SECA1_STRPN
Sequence: MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKSPMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDLAPEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PARNL_ARATH
Sequence: MQRRFLSSISATAGNTKTLNQGRWSVKQVKKSNFHVTLDEIRTSIDSSDFIALSLQNTGSYAAAWHRVSAIDTPQTSYLKAKYAAERYQILQFALCPFSLQGSKLTVHPYNFHLFPRDELKCGMPSYSFSCQASRLTAMAREGFDFNICIYEGISYLSRAQESASKFLSENPILADSVTVSSSPATVADTVFVGRIRSRVKNWRQSCIDSGSKTGDDDLVSSLRRLVLGSEQYGSRLCLTIDVCSERQVQLILEMLTEFSDDVVPLLVASKSRGTQAVRTVFMSSKEDKDLFKRELKDLEKEENRRVRGFREVVDFISSSQKPVVSQNYLSDFTSIHAKFLGPLPSNVDDFSSSLSSAFPNVVDLSQFMKEISPLSNISNLPAAMSSLNRFFAPVDVEVANQGCPVKLDEGHQSHGQNAVMISQLFAKLCTIQKSDLSTIQSNEDFQALASDEHANSVTSCSKNAGDENVKVWSKNSRRVSSENLVFIWGLGKKMTAAKLKNVLQKSHPVFAREFDVKYIDRSSAILVFWESGPSETFLSAVNNEEQLDGSLREMVAEGLRGAGYETYKRACRLGFWEADLAESLDKALESSDTDPDSDTKPSEIDWSNELAINFDEL
What is the function of this protein?
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails.  Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs (By similarity).
What are the official names of this protein?
Poly(A)-specific ribonuclease PARN-like, Polyadenylate-specific ribonuclease-like protein.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: BR2D_PELRI
Sequence: GILDSLKNLAKNAAQILLNKASCKLSGQC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Brevinin-2Rd.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: Y4227_DICDI
Sequence: MSNKNKKIVQGEEDEEEDDLYDDYDDKPKTTTTTTTSTSMNKSDSNISLNKEMLINDHPEDLIVGANSPLNVSVTTTPIENINENPSPVNLDEQTQQTQPQQNPISPITPLSSSSPSSSTTTTTITNSAVSPSNILITPTQSPIEIKPIIETQQPLPSPPQQGPSPIILQHQQQQQPLQSQYITPPIPQPQYQPIASQQSQQPQQIPTRKLSGSQMLPQRIPLSLGENKLKEFNENLRKSYCTKTHMLYYSINKEVSGANQHLTGVIDLIKSVQHNIRQYNDDILTLEEKLEQTEWSLQYYFNNNSNNNS
What are the official names of this protein?
Uncharacterized protein DDB_G0292106.
Protein: RHLB_PSYIN
Sequence: MNKTHLTQTKFADLPLEKSLISGLTSQGYEYCTPIQALSLPITLTGKDIAGQAQTGTGKTLAFLPAVFHHLLTNAQPENRRKNQPRAIILAPTRELAIQIHKDAMVLASMSNLRLGLAYGGEKVEIQRTKLEKGVDILIGTTGRTIDFVKQGVIDMGSIQSVVLDEADRMFDLGFIKDIRYLFRRMPEAKSRLNMLFSATLSHKVQELAFEHMNDPESIQIEPEVMTSVNITEELFYPSNQDKILLLLSLIEEDWPDKAIVFANTKHTCEKVWGYLAGDGLRTGLLTGDVPQNKRLKILQQFTDGEIDILVATDVAARGLHIPKVSHVFNFDLPDDCEDYVHRIGRTGRAGEKGLAISFACEKYVFNLPAIEEYIKHPIPCSEYDKNAMLDSLPVMKVTKYKAHPNSRKDNYHRTHKR
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP23_CANAL
Sequence: MSTAAPQENSPELKLSPSSKLNGFEWWRRTLSYQTGLGLNAEEKAQYEFDYNNRNLAEKCQQCNEYRNWMLEYSPSVLFMMDHIKKLTKDKEPILTKENITCDVCDFTKGGGFHPDEGILLCANWIRNKWQLEDILTHELVHVYDYLKFNLDMNNLRHHACTEIRASMLSGECRIWQEIKKTGLGNFGKKFQDCIKRRAVLSVSSNPICKSPEEAEKVVSTVWNSCFNDTRPFERVYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: Y1832_CHLTE
Sequence: MSPISQKGEAVCLSVRVQPRSSKSGVAGMYGEQLKICLKSAPVDNAANKECCELLAKALGVPRSSVSVMKGASSRSKVLKVEGVTPAAVREALVGMLGDEAEAGA
What are the official names of this protein?
UPF0235 protein CT1832.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: ACP_ECO8A
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTN_ECOLI
Sequence: MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTAQRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGASAVANLEPQ
What is the function of this protein?
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
What are the official names of this protein?
Multidrug resistance protein MdtN.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: CLPS_ECO45
Sequence: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: DCOR_CANAL
Sequence: MKHTIIENEPEIKLQNDLNHHIEISPNTKTTNGTTTTTTTLNVNKTLKAIDLIETSIKNHISTIDHENCLPNDEDSFFVCDLGEIINSVNQWQQILPMVQPYYAVKCNSNPQILTTLSELGVNFDCASKNEIDLVLSLGIHQAHERIIYANPCKTNSFIRHAADENVNLTTVDNVHELYKLAKFHPHCKILIRLITDDSTAQCQLSTKFGCDLNTAIGEILPKAKELGLQVHGVAFHVGSGAKDFSSIYQAIKDSRILFDEMLSMGFTPKLLDIGGGFERETFPQSSQMVKFALEKFFPIEFSQLNEIKFIAEPGRFMVANAFTLITHIIARRDLPTGGNNNNNDMTPSAMLYINDGVYGNLNCILFDHQTPKVYVLTNENQLFYKQEMMRSLSVNNNNNNNNKTDGFKFSIWGPTCDGLDCVSSLAKLSKNVQVGDWLFFENVGAYTSCASTKFNGLSSGETKTLYVNSNEE
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_STAAE
Sequence: MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVSVYLEEMDQRNAVIIK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: DPO3A_RICTY
Sequence: MQSEFIHLRTQSSYSFLESALTIEKVVELALLHKMPALCLSDRGNLFGSLEFALYAVKKKLQPIHGVILNIQYDINVFAQILLIAKDETGYKNLLKLSSLTFTKNDRKICDHINFEDLIKYQEGLIALCCYTDGIVGKCLLARKQEHAIMFARRLQAILGDRFYFEIMRHDLPEEQFIENSYIQIASELSIPIVATNKVLFSEKSMHYAHDVLLCISEGVTKEYPDRKTVSENCYFKSPAEMKKLFSDLPNAIQNTVNLRERCYFAAHPNPPMLPNFSTQDISETYLIRKYAKEGLLARLVTKFKAENISREHQEKLKTEYFTRLNYELDIICNMNFAGYFLIVSDFIKWSKKHGILVGPGRGSGAGSVVAWSLLITDLDPIKFGLLFERFLNPERISMPDFDIDFCQERREEVINYVCSKYGNNRVGQIITFGKMQAKAVIKDVARVLSLPYKCADYLTELVPFSAVNPVSLEQAIREVPELANAAKGKGLYNLEGDAELIKLVLDTSLILEGLHRHSSTHAAGIVIAGTDLVDIVPVYKDANSDMLIVGYSMKYSEIAGLIKFDFLGLQTLTVITNCKKLLKEQGIEIDFDDMTFDDNKTYQMLCKGKGVGVFQFESIGMKDALRRLKPDSIHDLIALGALYRPGPMENIPTYIACKHKLQQPDYLHKLLKPILEETYGVVIYQEQVQRIAQVLAGYTLGAADLLRRAMGKKIKKEMEEQEEIFVKGAIANNISQSQAKSIFATVAKFAGYGFNKAHAAAYGVISYQTAYLKANYPAEFLVACLNLELNNHDKINLFLQEAKDNGIKIIAPNINISEGYFSVKSSDTVITHNTKPLIPRLNNEIDIKDTAVKSLYYKDESTIIFALGAIKGVTPNFGKLVTDERKARGAFKSITDFIERLPPKSINSKLLENLIKAGCFDELHDNRLQLFLSVPKLIAYSTSYHQEQESNQFSLIKVSSLSPTILVSSNYADKNTLAFYEFESMGLFISNHPLTEYQEIFSRLNILNTRDLYNKLPNGTNQVTLAGVIQKKDSRMSARGRFVTLVLSDPENIFELTIFSEEVLKDYVHLLDVKSLVVVNCDIVKDEGGIKLTAKSFLSIEDAINNRQFELQLYPQNYAELEQIITLLVSRTGHGYQSNAKATIYLQSKDVKHFVAKITLSETFFLQVQDFEILSQYIR
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSF2_CHLAE
Sequence: MWLQGLLLLGTVACSISAPARSPSPGTQPWEHVNAIQEARRLLNLSRDTAAEMNKTVEVVSEMFDLQEPSCLQTRLELYKQGLQGSLTKLKGPLTMMASHYKQHCPPTPETSCATQMITFQSFKENLKDFLLVIPFDCWEPVQE
What is the function of this protein?
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
What are the official names of this protein?
Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF.
What is the protein family that this protein belongs to?
Belongs to the GM-CSF family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIK6_GIBF5
Sequence: MNEESNMGGVFKEEEAQSGDVVDFEGDSDTHNPQNWPMGKKVYTTALWALTTCWITFASAIYSAGTAEISEEFHVSYEVANAGTSLLIFGFALGPMLWAPLCEVYGRKWPALAPYFISAAFAFGTATAKDIQTILITRFFAGVFGSSPISITGGSIVDIWTPRQRGTPMVCYGITIAAAPTLGPIIGGAFIASGCGWRWTEYLTGIVMMVQFVLDALWLDESHADVLLTRKASRLRRSTGNFSLHAKWEETSPTFKSLLSTYLVRPFQMLLDPICLLLTIYTSFVYAILYASLESFALEYGRFRRWGPVVSQLPFLSLLIGCLFAAAANIFNNIYYGKKLVANNFKPVPEARLPPMMVGGFAFSAGLFLFGWTSVEHVSSPWPSIIGVFLTGVGFTTIFQSSLQYLVDTFTRYSASAIAANTFVRSMAAGAFPLFVWPMYEKIGIDWGSTIFACISVLLLPAPFLFFKWGYRIRARGEFSKLSTY
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of bikaverin, a red pigment also considered as a mycotoxin (PubMed:19400779).
What are the official names of this protein?
Efflux pump bik6, Bikaverin biosynthesis protein 6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CDMD_TALVE
Sequence: MTVTINKSSVPHKVDFATPLSDVICHIKEDGAVIVRGFMDVETIQKLQEEVDTAVEKGSFGPRYQEYNEEAGEIPKHEIYKRGEGKKTKHMKNLALTSETFRNDVLNHKWMHAVCEQIYGEEFGDYWMNCAHILHLEPGEKAQFFHRDTGVYRVSDFRRRLNDPEFMINFLVSLTEFREDNGATQLIPGSHKWDAAHPPTFYGSDEAVPAILEPGDAVVYLGSLFHGAGENRSLDYRRGMIVSMHPAHFTPMESHFHLPKEIVESMTPLAQQMVGWRTMNNQNKIPIWQAGDDKIEDVLRLQHKEVY
What is the function of this protein?
Dioxygenase; part of the gene cluster that mediates the biosynthesis of chrodrimanin B, a meroterpenoid that acts as a potent blocker of insect GABA-gated chloride channels (PubMed:30417647).  The first step of the pathway is the biosynthesis of 6-hydroxymellein by the polyketide synthase cdmE (PubMed:30417647).  The prenyltransferase cdmH acts as a 6-hydroxymellein 5-farnesyltransferase and produces the hydrophobic metabolite verruculide C (PubMed:30417647).  The FAD-dependent monooxygenase cdmI further converts verruculide C into verruculide B (PubMed:30417647).  The terpene cyclase cdmG then produced the pentacyclic molecule 3-hydroxypentacecilide A, the backbone structure of chrodrimanin B, via folding the farnesyl moiety of the substrate into the chair-boat conformation (PubMed:30417647).  The short-chain dehydrogenase/reductase cdmF functions as the 3-OH dehydrogenase that oxidizes the C-3 hydroxyl group of 3-hydroxypentacecilide A and produces chrodrimanin C, the dehydrogenated product of 3-hydroxypentacecilide A (PubMed:30417647).  The cytochrome P450 monooxygenase cdmJ then accepts both 3-hydroxypentacecilide A and chrodrimanin C and functions as a C-7-beta-hydroxylase to produce respectively chrodrimanin H and chrodrimanin F (PubMed:30417647).  The dioxygenase cdmA accepts chrodrimanin H to afford chrodrimanin E, which is further transformed to chrodrimanin A by the dioxygenase cdmD (PubMed:30417647).  CdmA can also accept chrodrimanin C as substrate to convert it into verruculide A, which is further converted into chrodrimanin T by cdmD (PubMed:30417647).  The last step of the biosynthesis is proposed to be performed by the acetyltransferase cdmC which acetylates chrodrimanin A to yield chrodrimanin B (Probable).  The pathway may also lead to the production of additional shunt products, including chrodrimanins T and U (PubMed:30417647).
What are the official names of this protein?
Dioxygenase cdmD, chrodrimanin B biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: DAPF_RHILW
Sequence: MSATVEFARMNGLGNKILVVDMRGRPDKVTPAAAVALNADPQTEFDQIMAIHDPKADGTDAFIDILNSDGSKAQACGNGTRCVVQALAAETGRKAFTFQTVAGILNAVEHEDGTISVDMGRPVFDWNRIPLAEEFHDTSRIELQIGPIDNPVLHSPSAMSMGNPHAIFWVDRDVMSYDLARFGPLLENHPMFPERANITLAQVTSPTSMTTRTWERGAGLTLACGSAACSAAVSAARTGRTGRKVTINVASAKPPATLSIEWRERDDHVIMTGPAEWEWSGSLDPSTGLWSRDGTQEAGAR
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUB1_MOUSE
Sequence: MTLFQLLREHWVHILVPAGFVFGCYLDRKDDEKLTAFRNKSMLFQRELRPNEEVTWK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1, Complex I-MNLL, CI-MNLL, NADH-ubiquinone oxidoreductase MNLL subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB1 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.