PharMolix/UniProtQA huggingface dataset:
Protein: DAPF_MYCUA
Sequence: MIFAKGHGTQNDFVLLPDVAARLSLTAAQVAALCDRRRGLGADGILRVTTADAAVAAGVLHRLPDGVSPGDWYMDYRNADGSTAQMCGNGVRVFAHYLRASGLETRDEFVVGSLAGPRPVTVHHADQTHADVTVDMGKANKLGPGEAVVGGRRLSGVAVDVGNPHLACLDPGLTPEQLAALDVGAPVSFDHAQFPEGVNVEVLTARAAGVVCMRVHERGVGETRSCGTGTVAAAVAALASAGQETGTLTVRIPGGDVTVNITDATSLLRGPSVLVASGEISEEWWRDQRR
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSI3_ARATH
Sequence: MLKAFLPGTQEEETLSSLQSGKVDAKMEMDDPEKAMATVAQLIEQLHAKTSSPQDKELTTARLLGIAKGKREARRLIGSYGQAMPLFISMLRNGTTLAKVNVASILCVLCKDKDLRLKVLLGGCIPPLLSVLKSGTMETRKAAAEAIYEVSSAGISNDHIGMKIFITEGVVPTLWDQLSLKGNQDKVVEGYVTGALRNLCGVDDGYWRLTLEGSGVDIVVSLLSSDNPNSQANAASLLARLVLSFCDSIQKILNSGVVKSLIQLLEQKNDINVRASAADALEALSANSDEAKKCVKDAGGVHALIEAIVAPSKECMQGKHGQSLQEHATGALANVFGGMRHLIIYLGQVSQSPRLTEPIGDVIGALAYALMIFKQPESSENIFDPSVIESILVKLLKPRDTKLIQERILEAMASLYGNSSLSCYLDDAEAKRVLIALITMASADVRERLIICLSGLCHDKVGIWEAIGKREGIQLFISFLGLSSEQHQEYAVEMLKILTAQVDDSKWAVTAAGGIPPLVQLLETGSQKAKEDAACILWNLCCHSEEIRDCVERAGGIPAFLWLLKTGGPNSQETSAKTLVKLVHTADPATINQLLALLLGDDPTSKIQVIEVLGHVLSKASQEDLVHRGCAANKGLRSLVESLTSSREETKEHTASVLADLFSSRQDICGHLATDDIINPWIKLLTNNTQNVAKQVARALDALSRPVKNNNNKKKSYIAEGDIKSLIKLAKNSSIESAENAVSALANLLSDPDIAAEALAEDVVSAFTRILADGSPEGKRNASRALHQLLKNFPVCDVLKGSAQCRFAILSLVDSLKSIDVDSADAFNILEVVALLAKTKSGVNFSYPPWIALAEVPSSLETLVQCLAEGHTLVQDKAIEVLSRLCSDQQFLLSELIVSRPKSMLVLADRIVNASSLEVRVGSTALLLCAAKEKKQLITETLDQSGFLKLLLHALVDMIKHNSTSFSLETEVQTPKGFLEKNVFQDTGSFYFPDPAKILGGTVALWLLCILTSVDAKSKVIVMEAGGLEVLVGKLARYTSSAQAEFEDTEGIWISALLLAIMFQDDNVSFSSTTMRIIPTLAVLLGSDELIDRYFAAHAMASLVCTRNRGINLTIANSGAVSGIINLLGYVESEILNLVALANEFSLVKEPDQVILQHLFEIEDVRLGSTARKSIPLLVDLLRPIPDRPGAPQFAVQILIRIADGSDTNKLLMAEAGAVEALTKYLSLSPQDSTEYAISELLRVLFSNHELRQNEMALSSLNQLIAVLRLGSRSARYSAAGALNELFDAENIRNSEIACQAVQPLMDILGSVSESEQEVALSALIKLSSGNTSNTALLIDVEGSLLENVIKILSSATASEELKINAARLCSVVFSNKNIRTSASASGCMKPLITLMQSERSAAVEAAVFAIKILLDDEQHLELAAAHNIQELLVGLVSGKNYVIIEASLSALIKLGKDRVPRKLDMVEAGIIERCLELLPGASSSLCSAVVELFRILTNSGVIARRPDVAKTVEPLFAVLLRSDLTLWGQHSALQALVNILEKQQTLEAFSFTPSEAIVPLISFLESSSQAIQQLGAELLSHFLTMEDFQQDITTQSAVVPLVRLAGIGILSLQETAIKALEKISASWPKAVLDAEGIFELSKVILQEDPQPPLDLWESAAFVLSNILQYDAECFFRVELPVLVKLLFSTIESTVLLALKALMLHEKNDASSTVQMAELGAIDALLDLLRSHQCEEESGSLLEVIFNNPRVRELKLCKYAIAPLSQYLLDPHTRSEPGRLLAALALGDLSQHEGLSRSSGSVSACRALISVLEEQPTEEMKVVAICALQNFVMNSRTNRRAVAEAGGVLLIQELLLSCNPEVSGQAALMVKFLFSNHTLQEYVSNELIRSLTAALERGLWSTATINIEVLRTLNVIFSNFPKLRASEAATFCIPHLVGALKSGVEDVQGLVLDILYLLRHSWTNMSIDVAKSQAMIAAEAIPVLQMLMKTCPPRFHDKADSLLHCLPGCLTVNVMRANNLKQSMATTNAFCQLTIGNCPPRQTKVVSNSTTPEWKEGFTWAFDVPPKGQKLHIICKSKSTFGKTTLGRVTIQIDKVVTEGEYSGSLSLNHENSKDASSRSLDIEIAWSNRTTDETH
What is the function of this protein?
Regulator of the microtubular cytoskeleton (By similarity).  Microtubule-associated protein involved in the association of cellulase synthase (CESA) complexes (CSCs) and cortical microtubules.  Promotes dynamics of CSCs in the plasma membrane in both microtubules-dependent and microtubules-independent manners.  Regulates primary cell wall biosynthesis and cellulose microfibrils organization (PubMed:24368796).
What are the official names of this protein?
Protein CELLULOSE SYNTHASE INTERACTIVE 3.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Endomembrane system. Cytoplasm, cytoskeleton. Note=Colocalizes with cellulase synthase (CESA) complexes (CSCs) in a CSI1-dependent dynamic way. Present with cortical microtubules.
Protein: ATPB_MESM1
Sequence: MKNKGKIIQILGPIVDVKFNENQLPKLLNALTIEFEKTKITLEVAQHIGNDVVRTIAMSSTEGLVRNLEVIDTEAPISVPVGKNVLSHMFNVIGENIDNQSIDPNTEKWSIHRKAPSYEEQTATSEILETGIKVIDLLVPYVKGGKIGLFGGAGVGKTVLVQELINNIAVHHGGLSVFAGVGERTREGNDLYYEMKASGVLDKTALVFGQMNEPPGARMRVALSGLTMAEYFRDELNQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTRKGSITSIQAVYVPADDLTDPAPATTFIHLDAQTVLDRNIASLGIYPAIDPLASASRMLSADIVGEEHYKIAREVQRILQKFKELQDIIAILGMDELSDEDKNIVYRARKIRNFLSQPFHVAEKFSGIKGTFVKLSDTLRSFRDILDGKYDDLDESAFLYVGTIEEAKQKHLKNYKGDHVEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: MKS1_MOUSE
Sequence: MAEAVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAQMGKDLIDLATFRPPQAASGHRPDEEEEEEVVIGWQEKLFSQFEVDLYQNESACQSPLDHQYRQEILKLENSGGRKNRRIFTYTDSDRYTDLEEYCQKITTSASEVPSFLAERMANVRRRRQDRRGVEGSKLKSRIVTWEPSEDFIKNNHAINTPLQTMYIMADLGPYGKLGYKVHEHVLCILKVDSNGVITVKPDFTGIKGPYRIETEGEKQEHTSAWKYTIDNVSSLAQPEEEEREQRVFKDLYGRHKEYLSSLVGTDFEMIAPGALRLFVNGEVVSAQGYEYDNLYVHFFVELPAANWSSPPFQQLSGVTQACATKSLGMDKVAYFSFPFTFEAFFLHEDESAESLPEWPVLYCKVLSLDFWQRYRVEGYGAVVLPATPGSHTLTVSTWRPMELGLVAELRRFFIGGSLELEDPSYVRIPGTFKGERLSRFGFRTETTGTVTFRLHCLQQSRAFMESNSLQKQMRSVLDRLEGFSQQSSTHNVLEAFRRARRRMQEARESLPQDLVSPTGTLT
What is the function of this protein?
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Involved in centrosome migration to the apical cell surface during early ciliogenesis.  Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication.  Required for cell branching morphology.
What are the official names of this protein?
Tectonic-like complex member MKS1, Meckel syndrome type 1 protein homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: YIDH_ECOL6
Sequence: MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAPDFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLLIISLILMVVAVIVMGLVLYAG
What are the official names of this protein?
Inner membrane protein YidH.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2272.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 3SX7_OPHHA
Sequence: MKNLLLTFLVVTIVCLDLGYTLICHQVHGLQTCEPAQKFCQIRTTMFFPNHPVLLMGCTYNCPTERYSVCCSTDKCNK
What is the function of this protein?
This three-finger toxin binds and inhibits the nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Short neurotoxin OH-46, Three-finger toxin, 3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPLA_DICDI
Sequence: MNSKNDLFIGFFFFFYNYYYYYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIYIIVIIGLDPQQNHPSLKIPPPPSPTSPYVRRHARQHSRSNSSNSPGELTGGVEIIQQQNSINTQTSPPTSTSPNTVPPPPPTNTTTSSTTITRNSNNINNSNGGIINSSSGSNINNSSSSGVINTNINNSGGNISPTSNSLPSSNNNILYTSSGSNSGNNNNNNNTINISSGSSGINNSSNSNINNNNNNNSSSSSGIHASGSLTAIPTNTNSNSSIFHSSNSVNRINKSNYSADSLVLPPNRISQVPQSQTQPQLQISPSTSFSSQQQQQQQLQQQLQLQQQLQQQIQQQQQIQQQQNLHFTYSKTFTSGQPNTLVNLSSPPPQSKHLHVSSDHSFFNEVLTPTPVIHNSTNQNNQLLFGDSDPLSFLEYNNFINRYQPALKNNQPVSSYRQQQQIQHQIQLQQIQQQQQQQQQIQQQQLQQQQQIQQQQIQQQQQQIQQQQQQQQQQQQQQQQLQQIQPPPTIQPPPQQTTPTLRGNRSSGNLSGLNSFSLKQSTDSLTPPPNSQQSTVSSNSTPIAATPISPLTAPTSPPPPPPPPTNFNSKFNNNNNNNINNSSNNNTTVPPSPPPIIVLPKSPSSRSPRPASAPVPSAPFLVNNRVINTSSSSNISTNNTDLNLSSSSSSSPPLNISTASPSKSEDSPPTVSPSYKQQQQQQQQQQQQQQQLNNSSNSSYSPKPRSPSVSSPPPSSISPNSSPIGSPNISFHHHQQHQIPPPPPVLSNTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNHTNKKEGDSSWFNMSFKFFKKKLVPSNEYRWDLRKSNSLTLNIEDKSRCSYRLPTSGSKGIAKSTQPFSSSFTYFELFITNGNGDKICFGLTTNDHPIEVYPGNYQGSYGYSGDGKCYFGTNEGRVYGPSFSSGDVVGCGYDSSSKTLYFTKNGVYLGVAAQKVNLIGLYPTVGLQNPGESVVINFFGPFSYRGAPEKPSKQSTIKDSGGSSIIPSEDLIPKEEFEVCRWSEKKNYHGKHVVVRNRTAFLPLDSPKDTIGGVRATQPFGEGFCYFEVIIDQLDKGQLSIGLANLEYPTFYHVGWMPRSYGYHNDDGRKFRWREEPGVNEGESYGSSYKKGDIIGCGLSFTSREIFFTKNGMYLGTAFSNVYGVFYPSVAFNEPGISITGVFGPPFKFSQVTLMLKNVNSTSILVPNGNNNNNSNNNNNNNNNNIIGNGKITTTTTTSTSPSSINNNEDISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSSNTNNNNINNTTNNNNSNSNNNNNNNNSNSNSNSNNNNINNNNNNNNNNNNIYLTKKPSIGSTDESSTGSLGGNNSSGNNNSSSGSIGNNSSIIKQRSPPHSINGPLMLPPSSTNNNNNIYSSYNSTTAGSSTTILPTLNHPIFGNTTSNNNSSSTLSVGGNNNLLGRHCQSLPITASTNHTLSSSLGVSFSSPSSSPKTSPRKIVNSSEDLGFVQTFQDQDGQPPSAWRRCGKSIKTKDDITLTIIKKKTSVAMADRPFSSNSSSTICYFEVYLEGHDKKGSITVGLSHSTYPFIKHIGREPKSYGFSSEGEKYGGSEIGEPYGPFFFFDGDSIASSCVIGCGINTSTRDIFFTKNGHYLGVAFSRVTSDPLYPSISFRGVVGGLCVATFPGGHFRFNIEDLPGISPSVWTEALGPDRQGSGFKNWAPNDVAIWLESFNYGQYRKNFRDNNISGRHLEGITHAMLKNDLGIEPYGHREDIINRLNRMIQIWNDKSPDSYPKIAIDSSDKIRWPASGGSSGGINISGGVVIGSSSGSDDGITEISSSSKNIRPYKSYTQKEIEDRNRRSTISGGEKKNKYYIDNQMDPHQIGSMDSDGLLPDFGQGPPDEKNSSKTLSNEQIRYLQQRKDEPPIAISSTGNGGSVSSTGGSSGFLTFPSSNSLTHPPQRDKPTQEFTHLPPITSNYKGITNTGQPHKSFDQPLELFPRHSAFSNNGNNGNNNNNNNNNNIKANQQQQQQSSYQQSQTQQQQQHITSTSTSTTNKWIDPFGGWETQSSLSHPPSRPPPPPPPPPQLPVRSEYEIDFNELEFGQTIGKGFFGEVKRGYWRETDVAIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPNVVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNPHIRLKLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSRLKMEQASQMTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEMEDQGVSSFASVPVQTIDTGVYA
What is the function of this protein?
Essential for spore differentiation.
What are the official names of this protein?
Dual specificity protein kinase splA, Non-receptor tyrosine kinase spore lysis A, Tyrosine-protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Tyr protein kinase family.
Protein: PANB_SODGM
Sequence: MTTISHLRKWKQQQRKFTSITAYDAAFARLFAEQGIKVMLVGDSLGMTMQGHDSTLPVTLEDMVYHTRCVRRGAPSCLLLADLPFMSYATPAQTFENAAALMRAGANMVKLEGGAWLADTVNGLTARAVPVCGHLGLTPQSVNIFGGYKIQGRDAVGADQLLADARTLEQAGAQLLVLECVPVALAERVTHELSIPVIGIGAGAVTDGQILVMQDALGITGDSAPSFAKDFLAAGGDIAAAVRRYVQEVETGQFPAAEHSFQ
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_CYBMR
Sequence: MLLLINNLILNDVPTPWGLYFQDSSTPNQEGIIELHDNIMFYLVLILCTVSWLLFSIVKDSSKNPLPHKYLVHGQTIEIIWTILPAVVLLIIAFPSFILLYLCDEVISPAMTIKAIGLQWYWRYEYSDFINDSGETIEFESYVIPEDLLEDGQLRLLDTDTSVVCPVNTHIRFIVSAADVIHDFAIPSLGIKVDACPGRLNQVSALIQREGVYYGMCSETCGVAHSAMPIKIEVVSTKEFLTWLNEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DXS_BRUC2
Sequence: MSRPSTPLLDKAPTPDRLRALPEQDLPQLAEELRTELIDAVSTTGGHLGAGLGVVELTVALHHVFNTPYDRIIWDVGHQAYPHKILTGRRDRIRTLRQAGGLSGFTKRAESEYDPFGAAHSSTSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLVSGRTYRSVREAAKQVAQKLPKFLQDKARKSEEYARAFFTGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDTQKGPVLIHVVTQKGKGYAPAEAAADKYHGVNKFDVITGKQAKPPANVPSYTKIFGTSLIEEARHDDKIVAVTAAMPTGTGLDLFGEAFPKRVFDVGIAEQHAVTFAAGLASEGYKPFCAIYSTFLQRGYDQVVHDVSIQNLPVRFPIDRAGLVGADGPTHAGSFDTGFLAALPGFVVMAASDEAELRHMVRTAAEYDEGPISFRYPRGDGVGVDLPERGSVLEIGKGRIVREGTKVALLSFGTRLQECLAAAEELGAAGLSTTVADARFAKPLDHDLIRRLAREHEVLVMVEEGAVGGFGSHVLQFLATDGLLDRGLKVRALTLPDIYQDHGKPDAMYAEAGLDRTGIVRTVFAALHRDELGHEALPTPFRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RS20_COXB2
Sequence: MANSAQAKKRARQNEKRELHNASQRSAVRTAVKKILKSLQANDSSAAQSAYQHAVQILDKAAGRRIIHPNKAARLKSRLSQKIKNLSSSQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PYRG_MYCBP
Sequence: MRKHPQTATKHLFVSGGVASSLGKGLTASSLGQLLTARGLHVTMQKLDPYLNVDPGTMNPFQHGEVFVTEDGAETDLDVGHYERFLDRNLPGSANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITDEIKRRILAMAQPDADGNRPDVVITEIGGTVGDIESQPFLEAARQVRHYLGREDVFFLHVSLVPYLAPSGELKTKPTQHSVAALRSIGITPDALILRCDRDVPEALKNKIALMCDVDIDGVISTPDAPSIYDIPKVLHREELDAFVVRRLNLPFRDVDWTEWDDLLRRVHEPHETVRIALVGKYVELSDAYLSVAEALRAGGFKHRAKVEICWVASDGCETTSGAAAALGDVHGVLIPGGFGIRGIEGKIGAIAYARARGLPVLGLCLGLQCIVIEAARSVGLTNANSAEFDPDTPDPVIATMPDQEEIVAGEADLGGTMRLGSYPAVLEPDSVVAQAYQTTQVSERHRHRYEVNNAYRDKIAESGLRFSGTSPDGHLVEFVEYPPDRHPFVVGTQAHPELKSRPTRPHPLFVAFVGAAIDYKAGELLPVEIPEIPEHTPNGSSHRDGVGQPLPEPASRG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ZDHC9_HUMAN
Sequence: MSVMVVRKKVTRKWEKLPGRNTFCCDGRVMMARQKGIFYLTLFLILGTCTLFFAFECRYLAVQLSPAIPVFAAMLFLFSMATLLRTSFSDPGVIPRALPDEAAFIEMEIEATNGAVPQGQRPPPRIKNFQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFILSLSLLTIYVFAFNIVYVALKSLKIGFLETLKETPGTVLEVLICFFTLWSVVGLTGFHTFLVALNQTTNEDIKGSWTGKNRVQNPYSHGNIVKNCCEVLCGPLPPSVLDRRGILPLEESGSRPPSTQETSSSLLPQSPAPTEHLNSNEMPEDSSTPEEMPPPEPPEPPQEAAEAEK
What is the function of this protein?
(Microbial infection) Through a sequential action with ZDHHC20, rapidly and efficiently palmitoylates SARS coronavirus-2/SARS-CoV-2 spike protein following its synthesis in the endoplasmic reticulum (ER).  In the infected cell, promotes spike biogenesis by protecting it from premature ER degradation, increases half-life and controls the lipid organization of its immediate membrane environment.  Once the virus has formed, spike palmitoylation controls fusion with the target cell.
What are the official names of this protein?
Palmitoyltransferase ZDHHC9, Zinc finger DHHC domain-containing protein 9, DHHC-9, DHHC9, Zinc finger protein 379, Zinc finger protein 380.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PLSY_LEGPA
Sequence: MALFIFLILVGYLMGSINSAIIVCRTFGLPDPREEGSKNPGATNVLRLGGKQYGIMVMVFDALKGILPVILAKLLSAEPVTVAFTALAAVVGHMYPVFFHFRGGKGVATTIGALLAFHFVIGVMVAATWLLVANFWRYSSLASIASISLAPFYSLILVGNLNIFPPLFMITILVLYKHRDNFNRLIDGKEPKIKFKHSVIEEIMEASPATSAEQEFPGKEVIDTNIDETEKTEQAEAVKKPKAKKATTKAKKTASKEETTKKPRSTKPKTKTVKEKE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AIM24_KLULA
Sequence: MWRRSISILRPSPTTVIPSNVLSGSQLELKPLFDNHAETTREDGSNVTTTQFQLLGDNPTLASIQVSPSIPLYVRHNSIVSIHDSDRLSNVNVSYNKWFTFWPTLSLSRFDKLVGTNTFNCLVSSRKSSDTLSVLQLNGTQDWIVLNPKSVVSFEGNSSLSIQWFHKWLNYFRWISNKVTVLRSYGKLSGRGNVLLNGNGSVYKLELKSEDDQIILQKNRILAFNGLNKLDFKQAVTFEQTSKSLESDSQPETIHNNEDKIAFMKTVNTTLEFLKTRWHTMSNTDFVRVKGPRTVLVQTDAKSSAQTWPTSTLSLKPAKNYLSFAKIDNGSVNFKNTTSLLEKK
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KATG_PSEP1
Sequence: MSNESKCPFHQTAGGGTTNRDWWPDQLNLRILHQHSSKSSPDPDFDYAKAFKSLDFQALKKDLTALMTDSQDWWPADFGHYGPLFIRMAWHSAGTYRIGDGRGGAGSGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGNKISWADLIVLTGNVALESMGFKTFGFSGGRADVWEPDEDVYWGSEKVWLGGDTRYGKDQVKAQPPGQGDLVAEPAKHGEEQNRDLSAERNLENPLAAVQMGLIYVNPEGPEGNPDPVASGKDIRETFGRMAMNDEETVALIAGGHAFGKTHGAGPADNVGPEPEAAGLEMQGLGWHNTFGSGKGGDTITSGLEVTWTSTPTRWSNEYLNNLFDFEWELTKSPAGAHQWRPKEGKGAGTVPDAHDPGKKHAPSMLTSDLALRFDPIYAPIARRFKDNPEQLADAFARAWYKLIHRDMGPLARYLGPEMPNEELLWQDPLPKADPSTISEQDIATLKSRILASGLSVGELVSTAWASASTFRGSDKRGGANGARLRLAPQKDWAANQGVDKVLAALEKIRGEFNNGGKKVSLADLIVLAGTAAVEKAAKDAGYSGSVGFRPGRVDASQEQTDVESFAVLEPLADGFRNFTKARYSVKAEKLLLDKAQLLTLTAPELTVLIGGLRVLGANHGGSNLGVFTDKPGTLSNDFFRNLLDMSVEWKPTSADNETFEGRDRKTGQVKWSGSRVDLVFGSHAQLRALSEVYGSSDGGDKFVRDFVAAWQKVMELDRFDLK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: AT2A2_PIG
Sequence: MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGVKQKIMSVIREWGSGSDTLRCLALATHDNPMRREEMNLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQREACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFEGVDCAVFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS
What is the function of this protein?
Involved in the regulation of the contraction/relaxation cycle.  Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation.  Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca(2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca(2+) signaling cascades that promote osteoclast differentiation and activation.
What are the official names of this protein?
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ECHM_DICDI
Sequence: MLKQVIKTVSSSQAPKKYFFKQFCTSTTEKKGRVGLVTLNRPKSLNALSDGLISEINSAVKLFQEDKDVGSIIITGSEKAFAAGADIKEMEKVTLPDAYNNDLLAQWHDLTKIRKPIIAAVNGYALGGGCELAMMCDIIIAGEKAVFGQPEIKLGTIPGCGGTQRLIRAIGKSKAMELVLTGNNLTAVEAEKAGLVSKVVPVEELLTEATKMAEKIASYSQLTVAMAKEAVNASYELTLQEGIRFERRMFHSTFGTHDQKEGMNAFVEKRTPTWHNK
What is the function of this protein?
Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate.
What are the official names of this protein?
Probable enoyl-CoA hydratase, mitochondrial, Enoyl-CoA hydratase 1, Short-chain enoyl-CoA hydratase, SCEH.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: UGPB_YERPE
Sequence: MFNNSIHKVSICIALTLTFSANAMAVTEIPFWHSMEGELGKEVDSIADRFNQSQPDYKIVPVYKGNYEQSLAAGIAAFRSGKAPAILQVYEVGTATMMASKAIKPVYQVFKDANIDFDESVFVPTVAGYYTDSKTGRLLSQPFNSSTPVLYYNKEAFKKAGLDPEQPPKTWQELAADTAKLRAAGSSCGYASGWQGWIQIENFSAWHGQPIASRNNGFDGTDAVLEFNKPLQVKHIQLLSDMNKKGDFTYFGRKDESTSKFYNGDCAITTASSGSLASIRHYAKFNFGVGMMPYDADAKNAPQNAIIGGASLWVMDGKDKETYKGVAEFLQYLVKPEIAAEWHQKTGYLPITTAAYELTKQQGFYEQNPGADVATRQMLNKPPLPYTKGLRLGNMPQIRTVVDEELEAVWTAKKTPQAALDNSVKRGDVLLRRFEQANK
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Binds G3P.
What are the official names of this protein?
sn-glycerol-3-phosphate-binding periplasmic protein UgpB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.