PharMolix/UniProtQA huggingface dataset:
Protein: MNMA_SYNE7
Sequence: MERVVVGLSGGVDSSVAAALLHRQGYAVEGLTLWLMKGKGQCCSEGMVDAAGICEQMGVPYHVVDSRDRFQEAIVDYVVQGYEAGITPLPCSQCNRAVKFGPMLDYAKTELKADAIATGHYARLRQNPETGRTELLRAVDRNKDQTYFLYDLPQSVLQSVKFPLGELTKPETRQIAAELGLRTAEKPESQDLCLAEVHGSMRAFLDRYIESREGEIVDQSGRVLGKHTGIHHYTIGQRKGLGIAHSEPLYVIAIDPIQNRVVVGDRHSAAQSECTVSRVNWVSIAQPDAPIQAAVQVRYRSAPVPCTVIPLAGDRARILFADPQFSITPGQAAVWYDGDRLLGGGLIDRVERTTEPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_NOSS1
Sequence: MSRRGVIQRRPVPPDSVYNSRLVSMIIRRIMRHGKKSLAARIVYDALKTIEERTGNNALEVFERAVRNATPLVEVKARRVGGATYQVPMEVRTERGTTLALRWLVQFSRSRPGRTMASRLANELLDAANESGNAIRKREETHRMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: IAL1_MAIZE
Sequence: MASSVRAPSGSVIAVASSSSSAALAGVCGTGSPCAACKFLRRKCQPDCVFAPYFPPDNPQKFVRVHRVFGASNVTKLMNEIHPLQREDAMNSLAYEADMRIRDPVYGCVGVISILQHNLRQLQQDLARAKYELSKYQAAAAASASTAPTGPQAMAEFIGSAMPNGAAHNFINLGHSAALGSLGGSTAMFGQQEQFGSNAQMLSRSYDGGEPIARIGMNNGGYEFGYSSATTMGGSAGAVSGGLGTLGISSPPFLKSGTAGGDEKPSGGY
What are the official names of this protein?
Protein IAL1, IG1/AS2-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK2_EMIHU
Sequence: MAIRLYRAYSPGTRSRSSVYYTDITQQKPEKSLVFGKKACSGRNNRGIITLKGRGGAHKRKHRIIDFKRKSIATTARVATIEYDPNRNARIALLHYENGLKRYILAPRSLKVGMEVCSGPEAPIEIGNSLPLAAIPLGSTVHNIELTLGKGGQIARSAGTYAQIIAKEGDFVTLKLPSNEVRLVYKECYATLGQVGNIDAINTCLGKAGRSRWLGKRPKVRGVVKNPIDHPHGGGEGRSPIGRAKPVTPWGQPALGIKTRKKTKASGRYILRGRTK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COA3_CLAL4
Sequence: MAVIGAPKGHNRYRDPKTFQMTPALYRVRKPFFWKNFAGFFLVSSIPLGVYLYTWNVLSKDEFADIPIPPISDEELAKLKKEYESK
What is the function of this protein?
Required for assembly of cytochrome c oxidase (complex IV).
What are the official names of this protein?
Cytochrome c oxidase assembly factor 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COA3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: GATC_MAGMM
Sequence: MSVTKETVQHVANLARLQFNEEETERFSGQISRIVDLMDALSKLPTEGVKPMSHAVDMAIPQRDDVVTNGNQRDTMLANAPDAEKGHFRVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: KCY_NEIMB
Sequence: MNRQKVIAIDGPGASGKGTVAARVAAALGYDYLDTGALYRLTALYAQKQGVGWHDEENVSELAKKLPAVFSGSRILLGGEDVSDGIRTEAIGMGASAVAQLPKVRAALLQRQRDFLTEKGLVADGRDTGSVVFPQAELKIFLTAESKIRAERRAKQIGIPCEGLAFERILSDIEARDEADRNRKVAPLKQQPDALLLDTSRLTIEETVKKVLDWYREV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_KLEP7
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFTESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAEQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQAGLNASAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MURG_BACTN
Sequence: MEKELRIIISGGGTGGHIFPAVSIANAIIELRPDAKILFVGAEGRMEMQRVPDAGYKIIGLPIAGFDRKHLWKNVSVLIKLARSQWKARSIIKNFRPQVAVGVGGYASGPTLKTAGMMGVPTLIQEQNSYAGVTNKLLAQKAKAICVAYDGMEKFFPADKIIMTGNPVRQNLTKDMPEKGAALRSFNLQPDKKTILIVGGSLGARTINNTLTAALATIKENNDIQFIWQTGKYYYPQVTEAVRAAGELPNLYVTDFIKDMAAAYAASDLVISRAGAGSISEFCLLHKPVVLVPSPNVAEDHQTKNALALVDKQAAIYVKDSEAEAKLMDVALNTVADDRKLKELSENIAKLALPDSARIIAQEVIKLAEAEN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TXL1_LASSB
Sequence: MRSLTLAALLLCSLLLVFHTSAAAELEAQEGHLMIPGDTDTALETVDDERFFECTFECDIKKEGKPCKPKGCKCKDKDNKDHKKCSGGWRCKLKLCLKF
What is the function of this protein?
Is toxic to mice but not to insects.
What are the official names of this protein?
U1-theraphotoxin-Lsp1a, U1-TRTX-Lsp1a, LTx1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 04 (lasiotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IFB1_CAEEL
Sequence: MSSHKESSEYEMQYRSTIQPRTAVRSQSRQSGNYVSGGNGAGSGGRVLKMVTEMGSATVGGISPALSANAAKSFLEATDKEKKTLQGLNDRLGNYIDRVKKLEEQNRKLVADLDELRGKWGKDTSEIKIKYSESLSTARKDIDDAARRKAEVDVKVARHRDDLAEYRSRYEDIQQRRESDREKISQWTNAIADAQSEVEMLRARFKQLTDEEKRVTADNSRIWEELQKARSDLDDETIGRIDFQNQVQTLMEELEFLRRVHEQEVKELQALLAQAPADTREFFKNELALAIRDIKDEYDIIAKQGKQDMESWYKLKVSEVQGSANRANMESTYQRDEVKRMRDNIGDLRGKLGDLENKNSLLEKEVQNLNYQLTDDQRQYEAALNDRDATLRRMREECQTLVAELQALLDTKQMLDAEIAIYRKMLEGEETRVGLTQMVEQAVKTHSLQQQENTDSTRSVRGEVSTKTTFQRSAKGNVTISECDPNGKFIKLENSHRNKDENVGEHKIRRKLDGRREIVYSIPANVVIKPGKNLTIYARDQGGINNPPESLVFDGENTWGIGANVVTSLVNKDGEERATHTQKTIQSGQ
What is the function of this protein?
Cytoplasmic intermediate filaments provide mechanical strength to cells.  Essential protein, involved in attachment structures in epidermal cells that connect muscles to the external cuticle.  Required in morphogenesis and epidermal integrity.  Probable component of embryonic epidermal attachment structures.  Functions in larval muscle attachment independently of ifa-2.
What are the official names of this protein?
Intermediate filament protein ifb-1, Cel IF B1, Intermediate filament protein B1, IF-B1.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GT43E_ORYSJ
Sequence: MVSSRRNTGGIQRDGSLRDWSEFVDPSPSPKLLYSQSYVAMRGLLSSLVSMDFALLSSRLKSAWAAILSQRHTRSPERSKSRGLSCKRLAFHLFVCFMVGIFIGFMPFFSVDVSQKIVSENGRLPFDEGAVDRGMVDGKVKELETIVVEKEVDIIDESEVEESPPVPAMLDDEADFVESAPAIPDINDLDITVRKLLIIVTITTVRPQQAYYLNRLAHVLKTVQSPLLWLVVEWPDQSFQTAEILRSSGVMYRHLICRKNTTSVRKIAVCQRNTAIYHIKKHRLDGIMHFADEERSYMSDVFEEMRKIRRFGAWPVAIHTGIKYRVVLEGPICKGNRVTGWNTIQNIQKKSAVRRFPVGFSGFAFNSTMLWDPERWNRPPMDSVIVHSGGRGGLQESRFIEKLVKHERQIEGLPEDCNRVMVWNFNLEPPLLNVPPGWSLHKNLDAVIPVT
What is the function of this protein?
Probable beta-1,4-xylosyltransferase involved in xylan biosynthesis in cell walls.
What are the official names of this protein?
Probable beta-1,4-xylosyltransferase GT43E, OsGT43E, Probable glucuronosyltransferase Os05g0559600.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: ZN827_HUMAN
Sequence: MPRRKQEQPKRLPSHVSRQEEAEGELSEGEHWYGNSSETPSEASYGEVQENYKLSLEDRIQEQSTSPDTSLGSTTPSSHTLELVALDSEVLRDSLQCQDHLSPGVSSLCDDDPGSNKPLSSNLRRLLEAGSLKLDAAATANGRVESPVNVGSNLSFSPPSHHAQQLSVLARKLAEKQEQNDQYTPSNRFIWNQGKWLPNSTTTCSLSPDSAILKLKAAANAVLQDKSLTRTEETMRFESFSSPFSSQSASSTLAALSKKVSERSLTPGQEHPPPASSFLSLASMTSSAALLKEVAARAAGSLLAEKSSLLPEDPLPPPPSEKKPEKVTPPPPPPPPPPPPPPPQSLELLLLPVPKGRVSKPSNSASEEESGKPFQCPICGLVIKRKSYWKRHMVIHTGLKSHQCPLCPFRCARKDNLKSHMKVHQHQDRGETFQCQLCPFTSSRHFSLKLHMRCHQHFLRTEAKVKEEIPDPDVKGSPHLSDSACLGQQREGGGTELVGTMMTSNTPERTSQGGAGVSPLLVKEEPKEDNGLPTSFTLNAADRPANHTKLKDPSEYVANSASALFSQDISVKMASDFLMKLSAANQKEPMNLNFKVKEEPKEGESLSTTLPRSSYVFSPESEVSAPGVSEDALKPQEGKGSVLRRDVSVKAASELLMKLSAESYKETQMVKIKEEPMEVDIQDSHVSISPSRNVGYSTLIGREKTEPLQKMPEGRVPPERNLFSQDISVKMASELLFQLSEKVSKEHNHTKENTIRTTTSPFFSEDTFRQSPFTSNSKELLPSDSVLHGRISAPETEKIVLEAGNGLPSWKFNDQLFPCDVCGKVFGRQQTLSRHLSLHTEERKYKCHLCPYAAKCRANLNQHLTVHSVKLVSTDTEDIVSAVTSEGSDGKKHPYYYSCHVCGFETELNVQFVSHMSLHVDKEQWMFSICCTACDFVTMEEAEIKTHIGTKHTGEDRKTPSESNSPSSSSLSALSDSANSKDDSDGSQKNKGGNNLLVISVMPGSQPSLNSEEKPEKGFECVFCNFVCKTKNMFERHLQIHLITRMFECDVCHKFMKTPEQLLEHKKCHTVPTGGLNSGQW
What is the function of this protein?
As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (PubMed:33174841).  Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance (PubMed:25150861).
What are the official names of this protein?
Zinc finger protein 827.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: DCHS_MICSP
Sequence: MKKTDKILKEIGIQRVAIMEGKKYSKGFMEDGDIGVQY
What are the official names of this protein?
Histidine decarboxylase small chain, HDC.
Protein: DER_BACCQ
Sequence: MPKPVIAIVGRPNVGKSTIFNRIVGERVSIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAIDEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRSDIYDFYALGFGEPFPISGTHGLGLGDLLDEAAQHFPKIEEDGYDEDTIRFSLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYSKDGKDYVIIDTAGMRKKGKVYESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEENIRAHFQFLEYAPIVFLSAKTRKRTQTLIPVIDEVNESHSIRIQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVNDPELLHFSYERFLKNRLRESFGFVGTPIHIIARARD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: HS12B_HUMAN
Sequence: MLAVPEMGLQGLYIGSSPERSPVPSPPGSPRTQESCGIAPLTPSQSPKPEVRAPQQASFSVVVAIDFGTTSSGYAFSFASDPEAIHMMRKWEGGDPGVAHQKTPTCLLLTPEGAFHSFGYTARDYYHDLDPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKTMPALEVFAHALRFFREHALQELREQSPSLPEKDTVRWVLTVPAIWKQPAKQFMREAAYLAGLVSRENAEQLLIALEPEAASVYCRKLRLHQLLDLSGRAPGGGRLGERRSIDSSFRQAREQLRRSRHSRTFLVESGVGELWAEMQAGDRYVVADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGEDFIATFKRQRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALRRSSVNFVKWSSQGMLRMSCEAMNELFQPTVSGIIQHIEALLARPEVQGVKLLFLVGGFAESAVLQHAVQAALGARGLRVVVPHDVGLTILKGAVLFGQAPGVVRVRRSPLTYGVGVLNRFVPGRHPPEKLLVRDGRRWCTDVFERFVAAEQSVALGEEVRRSYCPARPGQRRVLINLYCCAAEDARFITDPGVRKCGALSLELEPADCGQDTAGAPPGRREIRAAMQFGDTEIKVTAVDVSTNRSVRASIDFLSN
What are the official names of this protein?
Heat shock 70 kDa protein 12B.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: EFTS_YERPY
Sequence: MVAITAALVKELRERTAAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRIAAEGIILAKVSADGKYGVILELNCETDFVAKDAGFKAFGEEVINAALAEKIADIDVLKAKFEEQRANLVAKIGENINIRRVAVLEGDILGTYLHGARIGVMVAATGADEELVKHIAMHIAASKPEYVKPDDVPAEVVAREHQIQLDIAIESGKPREIAEKMVEGRMRKFTGEVSLTGQNFVMDPSKTVGDLLKENNADVVNFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_ACIAD
Sequence: MMEVTAKLRGAAISAQKARLVADLIRGKSVAHALNILNFSNKKAAVLVKKALESAIANAEHNNSLDVDDLKVSTIYVDEGISLKRIMPRAKGRADRITKRTCHITVKVGV
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CLPS_VEREI
Sequence: MNFMATRAPTLPPATRPAPDDGGAVVLERRPEKTPPPQMYQVVMLNDDYTPMEFVIVVLQEFFSKDRETATRIMLKIHLDGKGICGVYSHDVAATKVDQVLDAALKAGHPLQCVSEPVA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RSMH_BIFLS
Sequence: MVDVANIHLPVLLDDCVNLMAPALEHENAVAVDCTLGLAGHSIAFLKTAPQARLIGIDRDSEALGLAAERMEREGLADRFIPVHAAFDQLDQVLTDRGIERVDAVFMDLGLSSLQIDETDRGFSYSHDAPLDMRMDVSQPLTAERILATYDAAELVRIFKEYGEERFSRQIARAIVAHRDKEPFTTTAQLNRLVDEVVPQAHRPAGNPAKRVFQALRIEVNGELDKLASTLPQAANRLHVGGRLVVESYHSLEDKTVKSFMAQGLRVDVPAGLPVIPPDAQPFFTDLTRGAIKADEHEIAANPRSASVRLRAVEVSRDIPSRWRKRFTQTAQGLNDINIQGSASPGRAKNTARIRTRRG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NBP1_YEAST
Sequence: MLKSVQGLWKDFFGIRDDGRKREYGSLDEVRKRSALRSRRKQMRPTGKSVLKRPRKVTDRKTEEKIRTNRRKTPKRRLTKIFQTIRDVFSNDNENMSKMQNVCGDMTRILKKRSQGRPSYMDTDTAKSRILRSDAFKRKISELKYNKQRISELRSGSSDGSSGKDRNQSLYLDREILLQRQIKKRDEKIKALESKLQSLQEALNYSNEKYRILEDLLDSSNIHPSYTKSRRTMSNLARENDEIKPLKIDLSPSPIRRTNSLFTSSPMKTYNRDGNIPEMQPLQENISPACPTPPYRSRETEKEDETLSPISVDFSSYLS
What are the official names of this protein?
NAP1-binding protein.
Protein: RNPH_TROWT
Sequence: MLFCCIICSVLRKNSRAHDEIRPVKIIRGWNIYAEGSALIAFGNTRVLCNATFQRGVPPFLRGQRSGWITAEYAMLPRSGTERSDRESVKGKISGRSHEISRLIGRSMRAILDRYALEENTIILDCDVLQADGGTRTAAITGSYIALYDALVWAKNQKILSKHPLTDSVSAVSVGLVGDQIFLDLDYSEDSNAQADINLVFTGSGKLVEIQGTAEKSPFSYGQFEQMMELAKTGCQALKEIQAASLD
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: CLSY2_ARATH
Sequence: MKKRGFYNLKHPFDPCPFEFFCSGTWKPVEYMRIEDGMMTIRLLENGYVLEDIRPFQRLRLRSRKAALSDCICFLRPDIDVCVLYRIHEDDLEPVWVDARIVSIERKPHESECSCKINVRIYIDQGCIGSEKQRINRDSVVIGLNQISILQKFYKEQSTDQFYRWRFSEDCTSLMKTRLSLGKFLPDLSWLTVTSTLKSIVFQIRTVQTKMVYQIVTDEEGSSSTLSSMNITLEDGVSLSKVVKFNPADILDDSQDLEIKQETDYYQEEDEVVELRRSKRRNVRPDIYTGCDYEPDTIDGWVRMMPYQFGKCAVNVESDEDEDDNNEDGDTNDDLYIPLSRLFIKKKKTNSREAKPKSRKGEIVVIDKRRVHGFGRKERKSELSVIPFTPVFEPIPLEQFGLNANSFGGGGSFSRSQYFDETEKYRSKGMKYGKKMTEMEEMMEADLCWKGPNQVKSFQKRTSRSSRSVAPKTEDSDEPRVYKKVTLSAGAYNKLIDTYMNNIESTIAAKDEPTSVVDQWEELKKTNFAFKLHGDMEKNLSEDGEGETSENEMLWREMELCLASSYILDDNEVRVDNEAFEKARSGCEHDYRLEEEIGMCCRLCGHVGSEIKDVSAPFAEHKKWTIETKHIEEDDIKTKLSHKEAQTKDFSMISDSSEMLAAEESDNVWALIPKLKRKLHVHQRRAFEFLWRNVAGSVEPSLMDPTSGNIGGCVISHSPGAGKTFLIIAFLTSYLKLFPGKRPLVLAPKTTLYTWYKEFIKWEIPVPVHLIHGRRTYCTFKQNKTVQFNGVPKPSRDVMHVLDCLEKIQKWHAHPSVLVMGYTSFTTLMREDSKFAHRKYMAKVLRESPGLLVLDEGHNPRSTKSRLRKALMKVGTDLRILLSGTLFQNNFCEYFNTLCLARPKFIHEVLMELDQKFKTNHGVNKAPHLLENRARKLFLDIIAKKIDASVGDERLQGLNMLKNMTNGFIDNYEGSGSGSGDALPGLQIYTLVMNSTDIQHKILTKLQDVIKTYFGYPLEVELQITLAAIHPWLVTSSNCCTKFFNPQELSEIGKLKHDAKKGSKVMFVLNLIFRVVKREKILIFCHNIAPIRMFTELFENIFRWQRGREILTLTGDLELFERGRVIDKFEEPGNPSRVLLASITACAEGISLTAASRVIMLDSEWNPSKTKQAIARAFRPGQQKVVYVYQLLSRGTLEEDKYRRTTWKEWVSCMIFSEEFVADPSLWQAEKIEDDILREIVGEDKVKSFHMIMKNEKASTG
What is the function of this protein?
Probable chromatin remodeling factor.
What are the official names of this protein?
SNF2 domain-containing protein CLASSY 2, Protein CHROMATIN REMODELING 42.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMG_CLOBH
Sequence: MKYSAGDFDVVVIGAGHAGCEAALASARMGCKTLICTMNLDSIALMACNPNIGGTAKGHLVREIDALGGEMGINIDHTFIQSRMLNTSKGPAVHSLRAQADKKRYSERMKHLLEKEDNVVLRQLEVIEIDVEDNEVKGVLTKNGAYFTTKAIILCTGTYLKGKIIIGDIIYSSGPSGLYPANDLSQSLLDLGINLRRFKTGTPARINKRSVDFSKMIEQPGDEKIVPFSFIHNKLDKDQISCYLTYTSEETHKIIHENIHRSPLYNGSIEGVGPRYCPSIEDKIVRFPDKDKHQIFIEPEGENTEELYVGGMSSSLPEDVQIKMYRSVPGLENAEILRTAYAIEYDCIDPQQLDLTLEFKNINGLYGAGQFNGSSGYEEAAAQGLIAGINAVLKIKEKNPLILKRSDAYIGVLIDDLVTKGTNEPYRMMTSRAEYRLLLRQDNADLRLTELGYKVGLVKEDRYNKFLNRKKNVENEIERLRNMQITGKREINEFLLEKGSTELKKPISLYELIKRPELDYFKVESLDDKRPSLSDDEKEEINIIAKYEGYINKQLEQVEQFKKYEDRLIPKSINYLDIKGLRLEAIQKLEKIKPINIGQASRISGVSPADISVLLIYMERKNREN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAC1S_CYPCA
Sequence: MESGSGGGGGGGVAALASFIMNEEELKRKQREKLKKLQATGGNPRPPRSLFFFTLKNPFRKTCINIVEWKPFEIIILLTIFANCVALAVFLPMPEEDTNNTNLTLESLEYIFLVIFTLECFLKIVAYGLLFHEGAYLRNCWNILDFVIVFMGLFTLVVDTINTIAGVPTEKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMSSILKSMLPLFHIALLVFFMVHIYAIMGLELFKCKMHKTCYYQGTNIIAVREGNEKPSPCAQAGHGRRCTINGTECRAGWPGPNFGITHFDNSCFAMLTVFQCITTESWTDVLYWINDAMGNDWPWIYFLTLILVGSFFILNLVLGALSGEFTKEREESRSRGEYQKLRERQQMDEDLEGYMEWITHAEVMDGDSEALLLLRKDTDSESDSLYQMLDQQVIYFYRLARRWNVVLRRKCHVWVKSKFFNWWVLLVVLLNTLVIAMEHHNQTEGLTSFQDTANVILLACFTIEMVMKMYAFGPRAYFMSIFNRFDCFVVTIGILEIILVVSNIMTPLGISVMRCIRLLRLFKLTRYWTSLNNLVASLLNSVKSIASLLLLLFLFIVIFALLGMQVFGGKFNFPDRVIQRSNFDNFPQALISVFQVLTGEEWDSIMYNGIMAHGGPQSPGILVSIYFIILYVCGNFVLLNVFLAIAVDNLAEAESLTAAQKEKAEEKARRKLMRTLPEKSEEEKALMAKRLMESRSKAEGMPTTAKLKIDEFESNVNEVKDPFPPADFPGDHEEVEPEIPISPRPRPMADLQLKETVVPIAEASSFFIFGPQHKFRKLCHRIVNHTTFTNIILLFILLSSISLAAEDPIDPRSFRNKVLAYADIVFTTVFTIEIVLKMTVYGAFLHTGSFCRNSFNILDLIVVGVSLLSMGMESSTISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAIKTIGNIVLVTMLLDFMFACIGVQLFKGKLYYCTDPLQKTAEECQGTFLKHVPNSLHDIEVHQRMWVNSDFNFDNVLNGMLALFTISTFEGWPEILYKAIDSNAVDTGPLYNNRVGISIFFIIYIIIIAFFMMNIFVGFVIVTFQKQGEQEYKDCELDKNQRQCVQYALKARPLKCYIPKNPHQYRVWYFVTSCYFEYLMFFLIMLNTLCLGIQHCNQSDHITKLSDTLNLIFTVLFTGEMIVKLIAFKAKGYFGDPWNVFDFIIVVGSIVDVVLSEVDAALEARGGLWCLHGCAEVNPMQAIAEAENVRVSITFFRLFRVLRLIKLLNRSEGIRNLLWTFIKSFQALPHVGLLIVMLFFIYAVIGMQMFGKVALVDGTEINRNNNFQTFPQAVLLLFRVATGEQWPKVILASMYGKLCDAKSDYGPGEEYTCGSSIAVFYFLSFYILCAFLIINLFVAIIMDNVDYLTRDWSILGPHHLDEFKKIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCPHRSACKRLISMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKSIWKRTSMKLLDQVIPPIGEDEVTVGKFYATFLIQEHFRKFMQRQEEYYGYRPTKKNADEIKAGLRSIEEEAAPELHRAISGDLIAEDDMERALEAGEEGIYRRTGGLFGLHTDPFSSEPSSPLSTQMTSQRPLQFVETRLEDIESPPDSVFLPNTEFFPDNMPTTTNTNNNANFVEDMSSRFTFENESLSAAATRNYSYEDIRGSSSYVGGASSVDDRRLSDFTVRTNITQFPYNPSYGPSKNQTATEASPATDKLIQQALRDGGLDSLAEDPKFVSVTRKELAEAINIGMEDMEGMAQGIVNRQSGKVTKRKRRPIPVPPGTKSTKPKENTSAV
What is the function of this protein?
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, gene expression, cell motility, cell division and cell death.  The isoform alpha-1S gives rise to L-type calcium currents.  Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.  They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines.  Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle (By similarity).
What are the official names of this protein?
Dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SO1B2_RAT
Sequence: MDHTQQSRKAAEAQPSRSKQTRFCDGFKLFLAALSFSYICKALGGVVMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGSILTALPHFFMGYYKYAKENDIGSLGNSTLTCFINQMTSPTGPSPEIVEKGCEKGLKSHMWIYVLMGNMLRGIGETPIVPLGISYLDDFAKEGHTSMHLGTLHTIAMIGPILGFIMSSVFAKIYVDVGYVDLNSVRITPNDARWVGAWWLSFIVNGLLCITSSIPFFFLPKIPKRSQEERKNSVSLHAPKTDEEKKHMTNLTKQEEQDPSNMTGFLRSLRSILTNEIYVIFLILTLLQVSGFIGSFTYLFKFIEQQFGRTASQANFLLGIITIPTMATAMFLGGYIVKKFKLTSVGIAKFVFFTSSVAYAFQFLYFPLLCENKPFAGLTLTYDGMNPVDSHIDVPLSYCNSDCSCDKNQWEPICGENGVTYISPCLAGCKSFRGDKKPNNTEFYDCSCISNSGNNSAHLGECPRYKCKTNYYFYIILQVTVSFFTAMGSPSLILILMKSVQPELKSLAMGFHSLIIRALGGILAPIYYGAFIDRTCIKWSVTSCGKRGACRLYNSRLFGFSYLGLNLALKTPPLFLYVVLIYFTKRKYKRNDNKTLENGRQFTDEGNPDSVNKNGYYCVPYDEQSNETPL
What is the function of this protein?
Mediates the Na(+)-independent uptake of organic anions such as taurochlate, bromosulfophthalein and steroid conjugates (estrone 3-sulfate, 17-beta-glucuronosyl estradiol, dehydroepiandrosterone sulfate) (PubMed:19129463).  Also transports prostaglandin E2 and L-thyroxine (T4) (PubMed:19129463).  Shows a pH-sensitive substrate specificity which may be ascribed to the protonation state of the binding site and leads to a stimulation of substrate transport in an acidic microenvironment (PubMed:19129463).  Hydrogencarbonate/HCO3(-) acts as the probable counteranion that exchanges for organic anions (PubMed:19129463).
What are the official names of this protein?
Solute carrier organic anion transporter family member 1B2, Liver-specific organic anion transporter 1, rLST-1, Sodium-independent organic anion-transporting polypeptide 4, OATP-4, Solute carrier family 21 member 10.
What is the protein family that this protein belongs to?
Belongs to the organo anion transporter (TC 2.A.60) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Note=Confined to the basolateral plasma membrane of hepatocytes.