PharMolix/UniProtQA huggingface dataset:
Protein: CH60_CLOP1
Sequence: MAKTLLFGEEARRSMQAGVDKLANTVKVTLGPKGRNVILDKKFGSPLITNDGVTIAREIELEDAYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVTAGANPILIRNGIKTAVEKAVEEIQKISKPVNGKEDIARVAAISAADEKIGKLIADAMEKVGNEGVITVEESKSMGTELDVVEGMQFDRGYVSAYMVTDTEKMEAVLDNPLVLITDKKISNIQDLLPLLEQIVQAGKKLLIIADDIEGEAMTTLVVNKLRGTFTCVGVKAPGFGDRRKEMLQDIATLTGGVVISDEVGGDLKEATLDMLGEAESVKVTKESTTIVNGRGNSEEIKNRINQIKLQLEATTSEFDKEKLQERLAKLAGGVAVVKVGAATETELKESKLRIEDALAATKAAVEEGIVPGGGTAYVNVINEVAKLTSDIQDEQVGINIIVRSLEEPMRQIAHNAGLEGSVIIEKVKNSDAGVGFDALRGEYKDMIKAGIVDPTKVTRSALQNAASVASTFLTTEAAVADIPEKEMPQGAGMGMDGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEAS2_HUMAN
Sequence: MSQVGRVRSSHHFESVCLDAEVRVVLVALDHAGLHTLSSALNESLRPIHREELHLLHFPNSPEENLRKRPAEPSPQIHGGAPHLPWLCVEKLDLLPENHAVFLQERTAQLFEGSFFFSRSPAHSISPLLQFRWGHCP
What are the official names of this protein?
Putative uncharacterized protein encoded by FER1L6-AS2, FER1L6 antisense RNA 2, FER1L6 antisense gene protein 2.
Protein: DCUP_RHOP2
Sequence: MTQKLVTKPFIEVLSGNRQASPPMWMMRQAGRYLPEYRATRAEAGSFLDLCFNAKLAAEVTLQPIRRFGFDAAIIFSDILVVPYALGRAVRFEVGEGPRLDPLNSPDLVGTLNGAIDLSKLEPVFEALRIVRSELAPETTLIGFCGAPFTVATYMVAGQGTSDQHPARLMAYQHPGAFARIIDVLVESSIQYLLKQLEAGADVLQIFDTWGGILPPREFEKWCIEPTRRIVEGVRKVSPGAKIIGFPRGAGAMLPDFIARTGVDAVSIDWTAEPNMIRERVQSKVAVQGNLDPLLLIAGGSALDQGVDDVLKNFSAGRHIFNLGHGITPDAPVAHVEQMVKRVRAYKG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROT22_LITRO
Sequence: AGDDETLLKPVLNSLDNLVSGL
What is the function of this protein?
Lacks antimicrobial activity.  Does not inhibit the formation of NO by neuronal nitric oxide.
What are the official names of this protein?
Rothein 2.2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Rothein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTS_CLOAB
Sequence: MSISPMMQQYLSIKENHKDCILFFRVGDFYEMFFEDAEVASRELELVLTGKDCGLEKRAPMCGVPHHAYAIYASKLVSKGYKVAVAEQLEDPSLAKGIVKRDVIKVLTPGTYTDSSFLEDTKNNYIMSLFIHDKVSAMCFADISTGEFNLTETELDFEIILNEISKFSPKELVLQENLDDKLVDKIRERFDVVYNRFSNEYFKEHRNENLKAQFSNYAEVNMTEGLKSCANGLIKYIIDTQKTALTHIDELQKYEIVDFLSIDINSRRNLELTETLKDKSKKGSLLWVLDKTSTAMGGRQIRKWIERPLIDDEKINLRLDAVEEMLTNVSYNEDLKELLKQVYDIERLAGKISSKSVNAKEMISLRGSIEKLPAIKKLIKNFNSELLVNMENALDDLGDIYKLLYESINDNPSLSIKEGNIIKEGYNKDIDELRLAKSHGKQWIASLENTEREVTGIKSLKVSYNKVFGYYIEITKSNLNLVPEGRYIRKQTLTNSERYITPELKEMEEKILGAEEKLVLLEYNVFCEIRERIEKEIDRIKGSAKILSELDCICSFADVARENNYCKPVIKRDGTLVIKEGRHPVVEKVIASGNFVANDTVINNSDNVMMLITGPNMAGKSTYMRQVGLIVLMAQIGCFVPASAAEISICDKIFTRIGASDDLNAGKSTFMVEMWEVSHILKNATKNSLILLDEVGRGTSTYDGLSIAWSVIEYICKSENLKCKTLFATHYHELTKLEGEIEGLKNYSIAVKKVNDDIIFLRKIISKGADESYGIEVAKIAGLPEEVLVRAREILKDLEEAKPKTAENTEDKKTNIVKEEPKKDSYQIDFNYLERESILKELKDTEIMDMNPIECMNKLYEFIKRAKKL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GLMM1_SHEB9
Sequence: MKERKFFGTDGIRGKVGSGQMTPELALKLGWAAGRVLSRSGTKKVIIGKDTRISGYMFESALEAGLSAAGLNVMLMGPMPTPAVAYLTRTFRAEAGVVISASHNPYYDNGIKFFSTDGSKLDDNLELEIEAELEKPLVCVESHLLGKVSRIEDARGRYIEYCKGNFPAEHTLTGLKIVVDCAHGATYHIAPAVFRELGAEVIAIGDKPNGMNINDKVGATSMGKICETVIAESADLGIALDGDGDRIMMVNSKGEVIDGDQILYILACDAKSRGVLRGGVVGTLMSNLGLDLALQALDIPFARSKVGDRYVMELLKELDWRIGGENSGHILNLDHGTTGDGIVAGILVLAAMRRQNATLEELTSAMEMLPQVLVNVRFEGEHDPLKSDKVKAAQAQVESELGVRGRVLLRKSGTEPLIRVMVEGDDHSAVLAHANLIADAVKSAS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MATP_SHISS
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVLLSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR6_PORPU
Sequence: MLQTKNSQEIKLNWYETVYLIKSDLNEDRTLCIINEYKSMLTNGGAKNIILQHRGRRHLSYSIKDYRDGIYVQVNYEGNGKLVQSFEKSLRFDENIIRYLTNKQNKDNKIEG
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: OR22B_DROME
Sequence: MLSQFFPHIKEKPLSERVKSRDAFVYLDRVMWSFGWTVPENKRWDLHYKLWSTFVTLLIFILLPISVSVEYIQRFKTFSAGEFLSSIQIGVNMYGSSFKSYLTMMGYKKRQEAKMSLDELDKRCVCDEERTIVHRHVALGNFCYIFYHIAYTSFLISNFLSFIMKRIHAWRMYFPYVDPEKQFYISSIAEVILRGWAVFMDLCTDVCPLISMVIARCHITLLKQRLRNLRSEPGRTEDEYLKELADCVRDHRLILDYVDALRSVFSGTIFVQFLLIGIVLGLSMINIMFFSTLSTGVAVVLFMSCVSMQTFPFCYLCNMIMDDCQEMADSLFQSDWTSADRRYKSTLVYFLHNLQQPIILTAGGVFPISMQTNLNMVKLAFTVVTIVKQFNLAEKFQ
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  Involved in the behavioral responses to esters.  Complexes with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  They are necessary and sufficient to promote functional reconstitution of odor-evoked signaling in sensory neurons that normally respond only to carbon dioxide.
What are the official names of this protein?
Odorant receptor 22b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SAR1_EMENI
Sequence: MWIINWFYDILASLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVAILSPTAHPTSEELVIGNNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFPESKAELDALLAMEELSKVPFLVLGNKIDHPDAVSEDELRHQLGLYQTTGKGKVPLEGIRPIEVFMCSVVMRQGYGEGIRWLSQYV
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated sar1-GTP binds to membranes first and recruits the sec23/24 complex.  These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to sar1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase sar1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS20_LACDA
Sequence: MPQIKSAIKRVKTQAVANERNAAQLSTMRTAVKKFKAAQAAGADNASELYVAAIRELDKAASKGLIHKNKATRDKSRLAKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SYK_PSYWF
Sequence: MSNQSTNDQDQIPSAEDTNDLIAQRQAKLDEISAAGKIAYPNQFKRTDYAEDLQKQFEGITKQEIEENAANGGKTQVSIAGRVMLNRGAFIVIQDMTGRIQLYVARKELDEDSLALIKSLDLGDIIGVSGYIGRSGKGDLYVHIEQITLLTKSLRPMPNKFHGLADTEARYRNRHLDLMTNESSRNTFMIRSQVISGIRKFMLNERFMEVETPMMHPIPGGAVARPFITHHNALDMPLYLRIAPELYLKRLVVGGFERVFEINRSFRNEGVSTRHNPEFTMIEFYQAYADYKDLMDLTERLFNQLAMDILGTTELTYQEETISLKAPFARLSMTDAIAQYAEGFDMSKVADRDYLADYAQNVLKQQVKEGFGIGKLQTIIFEETAEHKLRQPTFITQYPAETSPLARRNDENPEITDRFELFIGGREIANGFSELNDPADQAERFHNQVAEKDAGDDEAMHFDADYIEALAYGLPPTAGEGIGIDRLVMLFTDAASIRDVILFPHMRIKH
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_VIBVU
Sequence: MTFSIENNKQVVLGEELGKLSDNERLKTQSNFLRGTIEQDLQDRITGGFTADNFQLIRFHGMYQQDDRDIRNERAKQKLEPLHNVMLRARMPGGIITPKQWLAIDKFATEHSLYGSIRLTTRQTFQFHGVLKPNIKLMHQTLNSIGIDSIATAGDVNRNVLCTTNPVESELHQEAYEWAKKISEHLLPKTKAYAEIWLDGEKVETTEDDEPILGKTYLPRKFKTTVVIPPQNDVDVHANDLNFVAIAEKGKLIGFNVLVGGGLAMTHGDTSTYPRRADDFGYIPLEKTLDVAAAVVTTQRDWGNRSNRKNAKTKYTLDRVGTDVFKAEVEKRAGIKFEVSRPYEFTERGDRIGWVEGIDGKHHLTLFIENGRLLDYPGKPLKTGVAEIAKIHKGDFRMTANQNLIVAGVSKSNKAKIEKLAREHGLMDEGVSEQRKNAMACVAFPTCPLAMAEAERFLPQFVTDVEGILDKHGLDKEDNIILRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRGGTRVPKMYKENITDKQILEEIDQLVGRWANERLPNECFGDFTVRVGIIEEVIISKRDFYA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: Y1224_METJA
Sequence: MIILVMSMRDVEKIIKGIIKDMNPRFKRKTLRELLSEEKPHVIINGKRHRIKRRELEFLKEIASEDLKIPIVLEVDSSLGGAIKISGKEEVKVISKILGKEIDIFSEKDVMYIYKPELKIVRKELPTTTQLIFKLSLFD
What are the official names of this protein?
UPF0216 protein MJ1224.
What is the protein family that this protein belongs to?
Belongs to the UPF0216 family.
Protein: KCP1_BRANA
Sequence: MAGGGPTFSIELSAYGSDLPTDKASGDIPNEEGSGLSRVGSGIWSGRTVDYSSESSSSIGTPGDSEEEDEESEEDNDEEELGLASLRSLEDSLPSKGLSSHYKGKSKSFGNLGEIGSVKEVPKQENPLNKKRRLQIYNKLARKSFYSWQNPKSMPLLPVHEDNDDEEGDDGDLSDEERGGDVLARRPSFKNRALKSMSCFALSDLQEEEEEEEDE
What is the function of this protein?
Transcription activator which may regulates gene expression through interaction with the histone deacetylase HDA19.
What are the official names of this protein?
KID-containing protein 1, BnKCP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: NOL12_XENLA
Sequence: MGKKKQKKGQGSRLEVIFDEEKRREYLTGFHKRKMQRRKTAVEEIKRKIKEEQKKMKEERHKEYMKMLKEREEALCELEENDELEEMVTSKTESVRYDHPNHTVTVTTISDLDLSGIRVPPLGNAEQKQEEEKVEEENEKGADEEKPKTSVSLPKKSGDPFLSKKICSLTASLHARSQRKSGKRPSRTNENKKQTSSKMSGRTSKTQRRKQTGKTRRRRN
What is the function of this protein?
May bind to rRNA.
What are the official names of this protein?
Nucleolar protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRP17 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y228_NEIMA
Sequence: MIQHAGLGYRRDLAEDFLSLSENSPICFIEAAPENWLKMGGWARKQFDRVAERLPLALHGLSMSLGGQAPLDTDLIDGIKEMMRRYDCTFFSDHLSYCHDGGHLYDLLPLPFTEEMVHHTARRIREVQDRLGCRIAVENTSYYLHSPLAEMNEVEFLNAVAREADCGIHLDVNNIYVNAVNHGLLSPEAFLKNVDADRVCYIHIAGHDVETPELLIDTHGAAVLPTVWDLLELAYAKLPTIPPTLLERDFNFPPFAELEAEVAKIADYQTRAGKEYRRAA
What are the official names of this protein?
UPF0276 protein NMA0228.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: Y2481_STAAM
Sequence: MIHSKKLTLGICLVLLIILIVGYVIMTKTNGRNAQIKDTFNQTLKLYPTKNLDDFYDKEGFRDQEFKKGDKGTWIVNSEMVIEPKGKDMETRGMVLYINRNTRTTKGYYFISEMTDDSNGRPKDDEKRYPVKMEHNKIIPTKPLPNDKLRKEIENFKFFVQYGDFKDINDYKDGDISYNPNVPSYSAKYQLKNDDYNVKQLRKRYNIPTNKAPKLLIKGDGDLKGSSVGSKNLEFTFVENKEENIYFTDSVQYTSSEDTSYESN
What are the official names of this protein?
Uncharacterized protein SAV2481.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PSIE_SHIF8
Sequence: MTSLSRPRVEFISTILQTVLNLGLLCLDLILVVFLGKETVHLADVLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLIIVDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YEEN_SALCH
Sequence: MGRKWANIVAKKTAKDGATSKVYAKFGVEIYAAAKQGEPDPESNSALKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMVIAETLTSNVNRTIANIRTIFNKKGGNIGAAGAVSYMFDNTGVIVFKGTDPDHIFEILLDAEVDVRDVTEEEGNIVIYTEATDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGLVDALEDDDDVQKVYHNVANL
What are the official names of this protein?
Probable transcriptional regulatory protein YeeN.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK1_BOVIN
Sequence: MNGPVDGLCDHSLSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRETIQHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIMLAHRLNARMAELRRSGQLPWLQPDSKTQVTVQYTQDNGAVIPMRVHTVVISVQHNEDITLEDMRRALKEQVIRAVVPARYLDEDTIYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase isoform type-1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
Protein: TMCO6_HUMAN
Sequence: MWSRRQGRLRPTVCGVEELRRRRREREAALRKARREQQLVSKRLLRNDAPEEAGEGCVAAILGETEVQQFLRQAQRGTEEKEREGALVSLRRGLQHPETQQTFIRLEGSMRTLVGLLTSNQALLQLEAARCLHELSHSEQSTVAEACLPATSYLLTYLSSHSSDFIELCLYTLGNLIVESEAVRRQLLPQGIVPALAACIQSPHVAVLEALGYALSQLLQAEEAPEKIIPSILASTLPQHMLQMLQPGPKLNPGVAVEFAWCLHYIICSQVSNPLLIGHGALSTLGLLLLDLAGAVQKTEDAGLELLACPVLRCLSNLLTEAAVETVGGQMQLRDERVVAALFILLQFFFQKQPSLLPEGLWLLNNLTANSPSFCTSLLSLDLIEPLLQLLPVSNVVSVMVLTVLCNVAEKGPAYCQRLWPGPLLPALLHTLAFSDTEVVGQSLELLHLLFLYQPEAVQVFLQQSGLQALERHQEEAQLQDRVYALQQTALQG
What are the official names of this protein?
Transmembrane and coiled-coil domain-containing protein 6.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GSA_METPE
Sequence: MKTVSEDLYQKARGLMPGGVSSPVRAIAPYPFYTARGSGAVLTTIDGTDLIDCCLAYGPLILGHAFPAVQEAIAEQLQDGWLYGTPSLHEVRLAEQVIRDHPSIEMVRFVSSGSEATMAAIRLARGYTGKSDIVKVEGGFHGAHDAVLVKAGSGATTLGVPDSAGVLPDLVRHTLQVPYNDPEALEMLLSKHSDVAALIIEPVMGNIGPILPEENYLREVRSITTAHDVLLIFDEVITGYRLGIGGAQVCYGVTPDLTTLGKIIGGGLPIGAFGGRAEIMKLIAPAGPVYQAGTFNGNPLSMTAGTATLAWLSAHQEIYHHLDDETRAIEEAVIDSPAGAHGSFVRLGSLFKLFFRSSPPRDYIEAKQSDTTAFKEFWDQTLQSGIFLPPSQFETNFLSTAHTEQQIEAISAAYRSCRYE
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_THEM4
Sequence: MNEYIGQGNIKKRLGLAIKASKIRKEALDHVLLVGPPGLGKTTLAHIISNELGTNIHVTSGPILEKQGDVAAILTNLEHGDVLFIDEIHRMNRSVEEILYTAMEDFQIDILIGKGPSARSIRIDLQPFTLVGATTRSGLLSAPLRNRFGLIMELDFYSIDELSKIIERAAIVLNVEIEKDAAILLAKRSRGTPRIALRLLRRVRDMSTIRGKVKIDIYMVEEIMFLLGIDKEGLDELDRKILRTIIEVYNGGPVGVKSLAASVGISEDSISEVYEPYLLQSGFIARTHRGRIATKKAYNHLGIKVQRGLFDEE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SYY_STRPF
Sequence: MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIKGQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIETGISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDEIAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANELKQGLSNVPNYHVQSIDNHNIVEILVAAKISPSKRQAREDVQNGAIYINGDRVQDLDYQLSNDDKIDDQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_FUSNN
Sequence: MQFLFNIQLFAHKKGQGSVKNGRDSNPKYLGVKKYDGEVVKAGNIIVRQRGTKYHAGNNMGIGKDHTLFALIDGYVKFERLGKNKKQISIYSEK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: YPPF_BACSU
Sequence: MNVSYLSKRFAEMKKYETDCMNKLMDFAKFLYIQGHLSITEFRNSMKVLEANGAESPAYEMN
What are the official names of this protein?
Uncharacterized protein YppF.
Protein: RS1_STAAS
Sequence: MTEEFNESMINDIKEGDKVTGEVQQVEDKQVVVHINGGKFNGIIPISQLSTHHIDSPSEVVKEGDEVEAYVTKVEFDEENETGAYILSRRQLETEKSYSYLQEKLDNNEIIEAKVTEVVKGGLVVDVGQRGFVPASLISTDFIEDFSVFDGQTIRIKVEELDPENNRVILSRKAVEQEENDAKKDQLLQSLNEGDVIDGKVARLTQFGAFIDIGGVDGLVHVSELSHEHVQTPEEVVSIGQDVKVKIKSIDRDTERISLSIKDTLPTPFENIKGQFHENDVIEGVVVRLANFGAFVEIAPGVQGLVHISEIAHKHIGTPGEVLEPGQQVNVKILGIDEENERVSLSIKATLPNEDVVESDPSTTKAYLENEEEDNPTIGDMIGDKLKNLKL
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: LEUC_BIFLD
Sequence: MGTTLAEKVWADHLVRKGSDGAPDLLYIDLMLMHEVTSPQAFEGLRLAGRKPRHVDQLIATEDHNTPTVDIDRPNPDETSALQLTTLEKNCKEFGVRLHPLGDADQGIVHAFAPILGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVMATQTLSLKPFKTMAVNVNGKLPADATAKDIILAIIAKIGTGGGQGYVIEYRGEAIRNLTMDERMTVCNMSIEAGARAGMIAPDETTFEYLKGRPHAPEGELWDQAVAYWKTLKTDDDAVFDKVVDIDATKLGPYVTWGTNPGQGLPITASVPEPGKIADATKRAAAERAITYMGLKPGMPIKDIAVDTVFIGSCTNGRIDDLRQAAAIMKGHRKAENIHRVLVVPASSRVRLQAEKEGLDKVFKDFGAEWRNAGCSMCLGMNPDKLVPNERSISTSNRNFEGRQGKGSRTHLASPAVAAATAIRGTISSPADL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: ERO11_SCHPO
Sequence: MIGITKLISIWNAIWNFLLLPEIIISQTDTSSTGIYQMQSKVRSLVPVLTERSDYFSYYRVNLYRSSCPLWENDNAMCSNQGCAVKSLNEIEIPKVWKKLSDFEPHSKKNDTKCNWKYNPDLDYCYLDNSTSPDEYVYVSLVQNPERFTGYAGDHSAAIWRSIYEQNCFVVDDDDNPSEQPKSNALFRPNQIPLNLFTENHDDTSLSPSVACLEKRMFNRIISGFHASISTHVCQNYYDVEEQRWTQNLDWWRAKVGSFPDRIENIFFNYALLHQALVQIATQMKNITSDSSFTFCPTDKDVDWRTHTAFEQLVYHAYQDRHVINREQFFADEEAKRFKDSFRKHFRDISRIMDCVGCDKCRLWGKVQITGYGTALKLLLEPETQLSDLRPEEVVALVNTFDRISHSVEATFWFSLKAKTNDTLDAIKALIYKTYRSPSKEILAFFIDQTWYLFYALFFICNVPRVI
What is the function of this protein?
Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds.  Acts by oxidizing directly pdi1 isomerase through a direct disulfide exchange.  Does not act as a direct oxidant of folding substrate, but relies on pdi1 to transfer oxidizing equivalent.  Does not oxidize all pdi related proteins, suggesting that it can discriminate between pdi1 and related proteins.  Its reoxidation probably involves electron transfer to molecular oxygen via FAD.  Acts independently of glutathione.  May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress.
What are the official names of this protein?
ERO1-like protein 1, Endoplasmic reticulum oxidoreductin-1-like protein A.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: ATPD_YERPY
Sequence: MSEFVTVARPYAKAAFDFAVEHQAVERWQNMLAFTAQVTRNEQIAELLSGAVAPETMSTTFIAVCGDQLDEPAQNFIRVMAENGRLLVLPEVLQQFIQLRASLESTVDVEVSSARALNDEQLAKIAAAMEKRLSRKVKLNCKIDKSVMAGVVIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.