PharMolix/UniProtQA huggingface dataset:
Protein: TDXH_THEP1
Sequence: MEGRIPLIGEEFPRLEVKTTHGKKILPDDFRGKWFVLFSHPADFTPVCTTEFVAFQKRYDEFKKLNTELIGLSIDQVFSHIKWIEWIKEKLGVEIEFPVIADDLGEVSRRLGLIHPSKGTNTVRAVFIVDPNGIIRAIVYYPQEVGRNIDEILRAVRALQTSDEKGVAIPANWPSNELINDSVIVPPASSVEEARERLESKDFECYDWWFCYKKV
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_RICPU
Sequence: MIQMQSILEVADNSGAKKVMCIKVLGGSHHMVAKLGDVIVVSVKDAIPGGKVKKGDVYKGVIVRTKTGVVRPDGSTIKFDQNALVLLNKQDEPIGTRVFGPVTRELRAKKYVRIMSLAEEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ATPG_STAAS
Sequence: MASLKEIDTRIKSTKKMKQITKAMNMVSSSKLRRAEKNTKQFTPYMDKMQDAITAVAGASSNTNHPMLRPRKITRSGYLVITSDKGLAGAYSANVLKKLITDIEAKHQDSSEYSIVVLGQQGVDFLKNRGYDIEYSQVDVPDQPSFKSVQALANHAIDLYSEEEIDELNIYYSHYVSVLENKPTSRQVLPLSQEDSSKGHGHLSSYEFEPDKESILSVILPQYVESLIYGTILDAKASEHATRMTAMKNATDNATELIDDLSLEYNRARQAEITQQITEIVGGSAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BIOZ_AGRFC
Sequence: MQTRSSRMAGFGHAVPARCVDNAEIEASLGLEAGWIERRTGIRSRYWAEAGDTLSGLAERAGRMALEDAKINADDIALTLLATSTPDHLLPPSAPLLAHRLGLTRSGAIDLAGACSGFLYALTLADGFVRTYGRAVLVVAANILSRRINPAERASAVLFADAAGAVVLTPCPEVKRGVLSADLVADGSGYDLIQIAAGGSSQPFSAGMIAEDALMTMRDGREVFSRAVALMTNTSQRVLHEAELTAADISRFVPHQANARMSDAVCGNLGIEREKTVRTIGSFGNSSAATIPLSLSITNAERPLAGGETLLLTAAGAGMTGGAVVYRV
What is the function of this protein?
Involved in the formation of the biotin precursor pimeloyl-ACP (PubMed:33154364, PubMed:33824341).  Catalyzes the condensation of glutaryl-CoA, an intermediate in lysine degradation, with malonyl-ACP to produce 3-oxopimeloyl-ACP (PubMed:33154364, PubMed:33824341).
What are the official names of this protein?
3-oxopimeloyl-[acyl-carrier-protein] synthase, 3-oxopimeloyl-[ACP] synthase, 3-ketoacyl-ACP synthase, 3-oxoacyl-(acyl-carrier-protein) synthase, Beta-ketoacyl-ACP synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. BioZ family.
Protein: RL33_SACD2
Sequence: MRDKIRLNSSAGTGHFYTTTKNKRNMPGKFEIKKFDPVARKHVMYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS9_LACLA
Sequence: MAQVQYAGTGRRKNAVARVRLVPGTGKITVNGREVESYIPHADMRLVINQPFAATQTEGSYDTLVNVNGGGVSGQAGAIRHGIARALLQVDPDFRSALKRAGLLTRDARMVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RISB_VIBC1
Sequence: MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNITVVRCPGAVELPLVAQRVAKTGKYDAIVSLGTVIRGGTPHFDYVCSECNKGLAQVSLEYSLPVAFGVLTVDTIDQAIERAGTKAGNKGAEAALSALEMINVLSEIDS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y153_MYCPN
Sequence: MNDWQWLKNRLVNAKTKAVSFWLAQTTSTILDIAELIKCCSDLKNTSINGLVDLINQQEKLEFNLTRLKEIDGEDARQLFGIEGNVYKHFQTELSRFYKQTRKHFRETGSESLFLGLPVIEGINEFNDVFRAPLLYVGVKLKVAPRLERFWLEINREEIFLNPTIIGVEINKRNSLFKNNYDTTKVDINQALEIFRELEYQFRMPLTSELKSFSKKAKSDFNTEKRTNFLTNNVLLGIFDVKGDQLFQNFNEILNTDPDVLDELLKDRRDLLYDNREFRENFNLKGTYLFSHLDIFQQYAVKQAFDGDVIIEGPPGTGKSETIVNILVNLALNKKKVLFVSEKVTALDVVYNRLGSFKHIALFNASVASEKKRFYSQFADYESFFTDNFSKKDLVNEMPVFDGQWVDKILSEFTNLQNIYDTQINSGNQSYSFKEILSSFPILDVSYIKIKEHDRFDEWVRVFSSQVWLEKHLTYLAFKAELSKRWQNIDNFYALKDLLEKRKNIRVLCYVLDYFEQNNSIIKPKRVLLYTPTERGQKQLHQLQQDVAKYNSLQRFKSAAKFETIKLNLANKLAQNAKPFFFSWFIQTHAQTLLENLVQTQKQLVKAKQSYLSKIEQYVVSCKRILKATILANFFELYQTNKNELLDICREAKNPVLKEITWWFKKNFALLSKLFPVHIMTFESAALLTPNQRRLYDYVVIDEASQVYLERAIPILYRGAKYIIAGDTKQLKPSNFFQARAEYDVDEEFEDGNVEAAVHSTSLLHFLKNRSRILTLLKFHYRSDSANLIAFTNNRIYNNELIFMNKATADKQVFIVHDVIDGIWRNNRNLQEARDVVQRLEQLTQTAEYQKSLGVICFNKNQAELIEYMIDKQNNPLLNEWRDRVNAQGEYVGLFVKNIENVQGDERDIIIFSLGYDRSVNSYGPISKQGGENRLNVAITRAKQRIELFKTNRASDYNGLSSNSLGSKLLVEYLLYCEAMANNQGESLDFQATQKQAPKAKYELELENQFFNELELIFGEQFTIKRNVNEGAYSFSFVFYFNENPYLAVDFNPALPHSRKEVSENIIYREQFLKKRKWNLVNIWLDEWKLNPGGVLQKLRNCLTHSENEFEEI
What are the official names of this protein?
Uncharacterized ATP-dependent helicase MG140 homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
Protein: DIUH_STOCA
Sequence: NKPSLSIVNPLDVLRQRLLLEIARRQMKENTRQVELNRAILKNV
What is the function of this protein?
Regulation of fluid secretion.  Stimulates primary urine secretion by Malpighian tubules and causes a dose-dependent stimulation of cAMP levels in the tubules.  May act as clearance peptide in that it may remove metabolic waste from the hemolymph.
What are the official names of this protein?
Diuretic hormone, DH, Diuretic peptide, DP.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: YP54_SCHPO
Sequence: MATLTETISKADKHDEKLTDFQYSKKIFNGVHEVEDDKQRTDFTTVRFGDVEKKFAVPKDYKYKNVLPTFPNAVYNLTGELAFEDKGLLADPKFSNLLKDVTKVEHLARDLGTVLYGIQLSKLNDAQKNELARYIAERGVVYFPDQEQTLEEFQELGQYYGHSHKHGSNSRPFEDKFAEFQVVYSDRFSPYDQHAKNNSLRYWHSDVSFEKQPSAQTFFKALTVPEQGGDTLFISGYAAYEALSTPLKKYLEGLTVVHSGKEQSEYHRRSGQHVRLDGDTNAHPIVRTHPVTGWKSLFISPGFTRYIPGIPRGESDAILDYLYQHIANLSQSTVRIKWTSNGVAAWDNRIVIHRATYDHLPQTRHLVRIAAQGEVPFFDANSHERSEDLRE
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase active on sulfonates.
What are the official names of this protein?
Putative alpha-ketoglutarate-dependent sulfonate dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the TfdA dioxygenase family.
Protein: MURD2_XANCP
Sequence: MRISQLEGKAVALWGWAREGRAAYRALRQQLPAQPLTVFCNAEEARDVAALADPALQVQTEASAQALAAFEVVIKSPGISPYREEARAAAAQGARFIGGTALWFAEHAQPDGYVPGAICVTGTKGKSTTTALLAHLLRADGHRTALVGNIGQPLLEVLSPQPPPAYWAIELSSYQTGEVGRSGARPELALVLNLFPEHLDWHGSEAAYVRDKLALVTDGRPRIALLNAADPHLAQLQLPESEVRWFNHPDGWHLRGDVVYRGQQPIFDTANVPLPGEHNRRNLCAVLAAVEALGLDAAALAPAALTFRPLPNRLQWLGSVDGIAYVNDSISTTPHASLAALACFAQQRVALLVGGHDRGLDWQEFAAHMAQQAPLEIVTMGANGPRIHALLAPLAQSAGFGLHAADDLAHAMQLARSALGAQGGVLLLSPGAPSFGVYSDYVARGRHFAQLAGFDPAAISAIPGLGVQ
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase, UDP-N-acetylmuramoyl-L-alanyl-L-glutamate synthetase, UDP-MurNAc-L-Ala-L-Glu synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKAI3_HUMAN
Sequence: MGCCTGRCSLICLCALQLVSALERQIFDFLGFQWAPILGNFLHIIVVILGLFGTIQYRPRYIMVYTVWTALWVTWNVFIICFYLEVGGLSKDTDLMTFNISVHRSWWREHGPGCVRRVLPPSAHGMMDDYTYVSVTGCIVDFQYLEVIHSAVQILLSLVGFVYACYVISISMEEEDTYSCDLQVCKHLFIQMLQIIE
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3, Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3, Protein FAM77D.
What is the protein family that this protein belongs to?
Belongs to the NKAIN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPD_SHEDO
Sequence: MAELTTIARPYAKAAFDFAIENNAVDSWAEMLNFAALVSENESMKPLLTGGLASGKLAALFISVCGEQVNTQGQNLIKVMAENGRLEVLAAVSELFTGYRNEWAKEVEASVVSAIELSSEQQQQVSVSLEKRLARKVKLNCSTDTTLIAGMIIRAGDLVIDGSVSGQLARLSDKLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CYB6_ACAM1
Sequence: MSKVYDWFEERLEIQAIADDVTTKYVPPHVNIFYCLGGVTLVCFIIQFATGFAMTFYYRPTVTEAFNSIQYIMTEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWITGVVLAVITVTFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGSSIVELLRGGTSVGQSTLTRFYSLHTFVLPWLIAVFMLLHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: COAA_STRSY
Sequence: MKNEFLNFEQIDRATWQQLHRKTTIPLSQSELNSIKSFNDRIQLHEVSDIYLPLVNLIHIYRKARKDLNFTKSLFLQKTIKPQPFIIGVSGSVAVGKSTTSRLLQILIARTFKYAKVELVTTDGFLQPNAVLEERQLLNKKGFPESYDMEKLIDFLDKIKNGYDCQIPVYSHEIYDIIPNKTQEIKSPDFLIVEGINVFQNPQNQRLYVSDYFDLSIYVDADVEHIETWYLERFQKLLTLAKNDPNNYYHRFTQMTYPEILSIAQNTWKNINLANLEKFIEPTRNRADIILHKAENHEIDKIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_DICNV
Sequence: MIESDRLVSGKARSEEQVIERAVRPKRLTDYVGQESLKAQLSIFIEAALKRQEALDHVLLFGPPGLGKTTLAAIIAFELGVGLRQTSGPILDKAGDLAALLTNLEPHDVLFIDEIHRLSPAVEEVLYPAMEDYQIDIMIGEGPAARSIKLDLPPFTLIGATTRSGLLTAPLRDRFGISHHLQYYHHDELTQIVMRSAKLFEVAIDKEGAEEIGRRSRGTPRIANRLLRRVRDYAQVRGDGMITKALADEALELLAVDHLGFDALDRRMLLCLVEYFGGGPTGIDTLAVSVGEERGTLEDVVEPYLIQQGFIQRTPRGRVATELAYQYLNIEVPDGRNS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SAFA_ECOUT
Sequence: MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRMARDLTHFIINSLLD
What is the function of this protein?
Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions.
What are the official names of this protein?
Two-component-system connector protein SafA.
What is the protein family that this protein belongs to?
Belongs to the SafA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: B2MG_MONDO
Sequence: MSRLFLFALLGHLCFLPYLDAITSSSGPPRVQVYSRYPPDSDKSNFLNCYVSGFHPPQITIELLKDGKKMENVEQSDLSFSKDWTFNLLVSAPFDPNSNSEFACKVTHSTLNEPKVVKWDKDN
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LSPA_STACT
Sequence: MKKPYFVSITLFITIAVLILDQVTKAVIAKSMAIGDSYTVIPKFLYITSHRNNGAAWGILSGRMSFFFIVTIVVLGLLVFFYIKEAKGNFLMQVAISLLFAGALGNFIDRMLHGEVVDFIDTKIFSYDFPIFNGADSSLTIGVILVLIALLFDSRKSKV
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LON_MAGMM
Sequence: MSEQRSDEPEVVDAIIEDQQGAQATTDATPPVRIENSLPTELVIYPLGGRPFFPGMLTPIQVEGSPYYETIKKAMDSHGRLFGILASHAEDGQEVFDANQLFGIGTVVRILEASVNEEAKQIKLLAEGLWRFEVRDVVSVGPPIVAQVTHHNNPVSVVDTDALKPYTMAVINTLKEILKYDSLYQEQVKMFLSRHNFSEPDRLADFVASMTSSSREELQEVLETLPIMARLEKVLTLLKKELEVVKLQNKIQRQVEEGIAEHQRQFFLREQLKEIQKELGITKDDRTAEIDRFRERLEKLTLSEEAEQKIEEELDKLAILETGSSEYGVTRNYVDWLTSLPWGVHSTDKLNIARARRILDRDHDGLEDVKERILEFLAVGKLKGEIGGSIILLVGPPGVGKTSIGRSVATAVGREFYRFSVGGMRDEAEIKGHRRTYVGAMPGKFVQAIKHTKVANPLIMLDEVDKIGASYQGDPASALLEVLDPEQNSEFLDHYMDVRFDLSKVLFICTANQLDTIPRPLLDRMEVIRLSGYITSEKVRIARNHLLPKQLEKNGLDKSQLRVSNGALREIIEGYAREAGVRRLEQKIGAIARKVAVKVLEEAELPISVGQNDLDSYLGKPDFREEKPLTGVGIVTGLAWTALGGATLDIESAQTSTEGNTLLLTGQLGDVMKESARIAFSFLQSNVEKLGGKSERLKGNIHLHVPEGATPKDGPSAGITIATALLSLARTQPLPRRLAMTGEITLTGSVLAVGGVREKVIAARRVGIRELIIPEACRKDYDEVPEHIREGFTVHFVKKYAEVAKLVFG
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_METFK
Sequence: MKTAQELRVGNVVMIGNDPLVVQKTEYNKSGRNAAVVKMKFKNLLTEAASEAVYKADDKFDVVILEKKEVTYSYFADPMYVFMDAEYNQYEVEADNMTDALNFLEDGMTCEVVFYNGKAISVDLPNSVVREITYTEPAVKGDTSGKVMKPAKIATGFELAVPLFCDIGDKIEIDTRTLEYKNRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_YERPA
Sequence: MKKGVLLNADISAVISRLGHTDQIVIGDAGLPIPATTTRIDLALTRGVPGFLQVVDVVTQEMQVENAYLAEEIVKNNPQLHEALLVLLTQLEQRQENQIALRYISHEAFKEQTKQSRAVIRSGECSPFANIILGSGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALT_KLEP7
Sequence: MLIPSKLSRPVRLEHTVVRERLLAKLSGANNYRLVLITSPAGYGKTTLISQWAAGKNDLGWFSLDEGDNQQERFASYLIAAIQQATGNHCAASEAMVQKRQYASLSSLFAQLFIELADWQRPLYLVIDDYHLINNPVIHDAMRFFLRHQPENMTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLTSPIEADDSSRLCDDVAGWATALQLIALSARQNNSSAQHSARRFAGINASHLSDYLVDEVLDNVDARTRNFLLKSSLLRSMNDALIVRVTGEENGQMQLEEIERQGLFLQRMDDSGEWFRYHPLFGSFLRQRCQWELAVELPEIHRAAAESWMAQGFPSEAIHHALAAGDAKMLRDILLNHAWGMFNHSELGLLEQSLAALPWSNLLENPRLILLQAWLMQSQHRYSEVNTLLARAEQEMSVEMDTAMHGDFNALRAQVAINDGDQDEAERLSMVALEELPLANYYSRIVATSVHGEVLHCKGKLTKSLAVMQQTEQMARRHDVWHYALWSIIQQSEILFAQGFLQAAWESQEKAFQLVREQHLEQLPMHEFLLRIRSQLLWAWARLDEAEACARQGMDVLSTYQPQQQLQCLALMVQCSLARGDLDNARSHLNRLENLLGNGHYHSDWVSNADKVRVIYWQMTGDKTAAANWLRQTPKPEFANNHFLQSQWRNIARAQILLGDFEPAEMVLEELNENARSLRLMSDLNRNLLLLNQLYWQSGRKSEAQKALLEALTLANRTGFINHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILRDINQHHRHKFAHFDEGFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: MKRN2_XENTR
Sequence: MNTKHVTCRYFLHGVCREGGRCLFSHDLATSKPSTVCRFYQRGQCAYGARCRYDHVKPCNGSVFYPPQEMAPAPLESTPPLLPTQEAAAPVTKSAPQRREKKSVVLRDRDLCGASVEKAHPDPALRPGCAADPPVSELEAKPHSYLEAICTGLDETPIPSAYPDAPQQLCPFAQAGGCHYGESCPYIHGNVCEICGLQVLHPYDQEQRGHHEKLCMANFERDMERAFAFQASEGKVCSICMERVYDKQSPSERRFGILSNCHHTYCLACIRQWRCARQFENPVIKSCPECRVISEFVIPSAYWVEDQSKKFELIEAFKQGMGKKACKYFDQGRGTCPFGGKCLYLHAYPDGTRAEPEKPRKQLGSEGTVRFLNSVRLWDFIEEREQRNLPDAEDEVAELGELFMHLSGVGEEPPAASN
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity).  Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway (By similarity).  Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase makorin-2, RING-type E3 ubiquitin transferase makorin-2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MTLD_SCLS1
Sequence: MGLKAVHFGAGNIGRGFVAEFLHKSGYEVVFCDVMDSIIQKLQTTPSYKVIQVGAEGTSEDTITNYRAINSKTHEADVIEEIRTADVVTCSVGPNILKFIAPVIAKGIDGRSNDATPIAVIACENAIGATDTLANHIKGDHTPQERLDDHHQRARYANSAIDRIVPAQDPDAGLDVKLEKFYEWVVDRTPFSDHEPPAIQGIKWVDDLIPYIERKLFTVNTGHAAAAYHGYYHQKATVYDALQDPNILKEVHAALEETSRLIVGKHGIEAQEQKDYVDKIITRIGNPHLEDAVERVGRAPLRKLSRKERFIAPAAELAEEGKDFTALLDAAEMAFRFQNVEGDEESKELAKIMSENSAEQVVEKVCGLQSDHPLFPHVVAVVKKVQADE
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase, M1PDH, MPD, MPDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RL16_CHESB
Sequence: MLQPKRTKFRKQFKGRIHGAAKGGTDLNFGAFGLKALEPERVTARQIEAARRAITRQMKRQGRVWIRVFPDVPVTAKPTEVRMGKGKGSVEFWACRVKPGRIMFEIDGVAEDIAREALRLGAAKLPIKTRFIQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MECA_MACCJ
Sequence: MRIERVNESTLKFYLTYTDIEARGFKRDDLWTSRKKGEEFFWSVMEEVNQEEDFFFDGPLWIQVHAFDKGIEVVVTKSKNDDLQLPEDDSDLNIDEKVNDFINNSMHSDSELRDLLMRASEESTEQFFIVHFDDLEDVIQFSYHNYEDVDIEDLLYMYEGKYYYYVEFDDHMSEDAIHSYIAHLLEYANETQISHEQLDEYGKIVMSHNVKRQVKQYFKQ
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: RUVC_GLUOX
Sequence: MIRLMGIDPGLRFMGWGIIDVDGNHLKHVASGVIGTDGSESVPLRLCELHGALKKLIREYAPAEAAVEETYVNRNGSSTLKLGYARGVALLTPAYEGLPVAEYGAMTVKKSVVGTGSASKEQVTMMVKRLLPGAEIRKADASDALAVAICHAHHRASAAHVVAGKRMA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CJ143_MOUSE
Sequence: MDSLASGRWRRRRTEELPAAGDAKRACRRSEPGGYECSGHMLTTCALLSWSTEDQEPRPRGLPASQPDCSQERLSSMVLQNGGRSSAQPCLRCISGESGHFNHTDNH
What are the official names of this protein?
Uncharacterized protein C10orf143 homolog.
Protein: YIDD_BURTA
Sequence: MQTVLIALLRFYKLAVSPLLGSRCRFYPSCSDYAREAIQYHGAARGTYLAARRLCRCHPFSAGGIDLVPPPNSDARNAPHEAEASSHRL
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.