PharMolix/UniProtQA huggingface dataset:
Protein: BPI_RABIT
Sequence: QKGLDYACQQGVAVLQKELEKIRIPDVSGKFKLRPFGKGHYNFHSLVVRSFQLPNPQIRLQPNVGLRVSISNANVRIGGRWKARKGFIKVRGKFDLSVEGVSISADLKLGSVPASGRATVTCSSCSSNINRARLRSQASWGGWLKLFHKRIESSLRNTMNSKICQVLTSSVSSKLQPYVETLPLKERLDSVAGIDYSLVAPPRATADSLDMQLKGEFYNVARPSPPPFMPPPMAIPSLHDRMIYLAISDYLFNTAALVYQQAGAFGLTLRDDMIPKESKSRLTTKFLGKALPQVAKMFPNMNVQLTLSVSSPPHLTTRPTGIALTAAVDLQAFAILPNSSLASLFLLGLKLNTSAKIGTKADKLVGELTLGRLILELKHSNIGSFPVQLLQALMDYVLSAVVLPKVNEKLQRGLPLPMPRKVQLYDLVLQPHQDFLLLGANVQHG
What is the function of this protein?
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.
What are the official names of this protein?
Bactericidal permeability-increasing protein, BPI.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule membrane. Note=Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Protein: NBAS_HUMAN
Sequence: MAAPESGPALSPGTAEGEEETILYDLLVNTEWPPETEVQPRGNQKHGASFIITKAIRDRLLFLRQYIWYSPAPFLLPDGLVRLVNKQINWHLVLASNGKLLAAVQDQCVEIRSAKDDFTSIIGKCQVPKDPKPQWRRVAWSYDCTLLAYAESTGTVRVFDLMGSELFVISPASSFIGDLSYAIAGLIFLEYKASAQWSAELLVINYRGELRSYLVSVGTNQSYQESHCFSFSSHYPHGINTAIYHPGHRLLLVGGCETAEVGMSKASSCGLSAWRVLSGSPYYKQVTNGGDGVTAVPKTLGLLRMLSVKFYSRQGQEQDGIFKMSLSPDGMLLAAIHFSGKLSIWAIPSLKQQGEWGQNEQPGYDDLNPDWRLSTEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKNLLGKSCEWFEPSPQVTATHDGGFLSLECEIKLAPKRSRLETRAGEEDEGEEDSDSDYEISAKARYFGYIKQGLYLVTEMERFAPPRKRPRTITKNYRLVSLRSTTPEELYQRKIESEEYEEALSLAHTYGLDTDLVYQRQWRKSAVNVASIQNYLSKIKKRSWVLHECLERVPENVDAAKELLQYGLKGTDLEALLAIGKGADDGRFTLPGEIDIDSISYEELSPPDEEPAKNKKEKELKKRQELLKLVNFSKLTLEQKELCRCRRKLLTYLDRLATYEEILGVPHASEQRYDAEFFKKFRNQNIVLSARTYAQESNVQALEILFTYHGSDLLPHRLAILSNFPETTSPHEYSVLLPEACFNGDSLMIIPWHEHKHRAKDWCEELACRMVVEPNLQDESEFLYAAQPELLRFRMTQLTVEKVMDWYQTRAEEIEHYARQVDCALSLIRLGMERNIPGLLVLCDNLVTLETLVYEARCDVTLTLKELQQMKDIEKLRLLMNSCSEDKYVTSAYQWMVPFLHRCEKQSPGVANELLKEYLVTLAKGDLKFPLKIFQHSKPDLQQKIIPDQDQLMAIALECIYTCERNDQLCLCYDLLECLPERGYGDKTEATTKLHDMVDQLEQILSVSELLEKHGLEKPISFVKNTQSSSEEARKLMVRLTRHTGRKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACYEIFTESLLCSSRLENIHLAGQMMHCSACSENPPAGIAHKGKPHYRVSYEKSIDLVLAASREYFNSSTNLTDSCMDLARCCLQLITDRPPAIQEELDLIQAVGCLEEFGVKILPLQVRLCPDRISLIKECISQSPTCYKQSTKLLGLAELLRVAGENPEERRGQVLILLVEQALRFHDYKAASMHCQELMATGYPKSWDVCSQLGQSEGYQDLATRQELMAFALTHCPPSSIELLLAASSSLQTEILYQRVNFQIHHEGGENISASPLTSKAVQEDEVGVPGSNSADLLRWTTATTMKVLSNTTTTTKAVLQAVSDGQWWKKSLTYLRPLQGQKCGGAYQIGTTANEDLEKQGCHPFYESVISNPFVAESEGTYDTYQHVPVESFAEVLLRTGKLAEAKNKGEVFPTTEVLLQLASEALPNDMTLALAYLLALPQVLDANRCFEKQSPSALSLQLAAYYYSLQIYARLAPCFRDKCHPLYRADPKELIKMVTRHVTRHEHEAWPEDLISLTKQLHCYNERLLDFTQAQILQGLRKGVDVQRFTADDQYKRETILGLAETLEESVYSIAISLAQRYSVSRWEVFMTHLEFLFTDSGLSTLEIENRAQDLHLFETLKTDPEAFHQHMVKYIYPTIGGFDHERLQYYFTLLENCGCADLGNCAIKPETHIRLLKKFKVVASGLNYKKLTDENMSPLEALEPVLSSQNILSISKLVPKIPEKDGQMLSPSSLYTIWLQKLFWTGDPHLIKQVPGSSPEWLHAYDVCMKYFDRLHPGDLITVVDAVTFSPKAVTKLSVEARKEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEVAVGPLDISPKDIVQSAIMKIISALSGGSADLGGPRDPLKVLEGVVAAVHASVDKGEELVSPEDLLEWLRPFCADDAWPVRPRIHVLQILGQSFHLTEEDSKLLVFFRTEAILKASWPQRQVDIADIENEENRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKEGLGNEVLKMCRSLYNTKQMLPAEGVKELCLLLLNQSLLLPSLKLLLESRDEHLHEMALEQITAVTTVNDSNCDQELLSLLLDAKLLVKCVSTPFYPRIVDHLLASLQQGRWDAEELGRHLREAGHEAEAGSLLLAVRGTHQAFRTFSTALRAAQHWV
What is the function of this protein?
Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:19369418).  Required for normal embryonic development (By similarity).  May play a role in the nonsense-mediated decay pathway of mRNAs containing premature stop codons (By similarity).
What are the official names of this protein?
NBAS subunit of NRZ tethering complex, Neuroblastoma-amplified gene protein, Neuroblastoma-amplified sequence.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: RL20_EDWI9
Sequence: MARVKRGVIARARHKKVLKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSRFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKVALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PYRB_ROSS1
Sequence: MSVPAEAGKRRDRRRHVLDLDDFSTQEIEEILETAVSMKEVLGRAIKQVPTLRGKTIVNMFFEESTRTRISFELAGKALSANVVNFTARGSSVEKGESLIDTVRTLQALGADMLVMRHSESGAPYLAAQYFHGSVINAGDGRHAHPTQALLDLFTVRQRLGRIEGLKVVIVGDILHSRVARSNLWGFTRMGASVTLCAPQTLIGPESFWKATWPDLTITSNLDECIKDADVIMTLRLQKERMEAGLLPSLREYSRFFAITAERVARAAPHCLVMHPGPMNEGVEIMPDVATSAQSVIEEQVANGVAVRMALLYRLSGE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL13_ORITI
Sequence: MKTYSAKPAEISKKWILIDATNLVLGRLAAKVAVVLRGKDKPTYTPHMDCGNNVIIINAEQVKLTGDKSNAKNGKFYYRHSGFPGGIKVTTAGKILQSNYPERIIQLAVKRMLPSNKLGRKQFSNLYVYKGQTHPHAAQTPVLYDFAGKNSKNIRNQNIV
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: 3HBH2_PSEAC
Sequence: MRSTNTRSARSRPTKRSVNASATPTQSFHRVDAHLSLLEGAEETGWVEFKTNTRVERIEQDADSVTVYDQNGNAYRGVALIGADGVRSVVRQTYVNDQPRVTGHVVYRAVVDKDEFPQDLRWNASSLWVGPKCHLVHYPLRGGEQYNIVVTFQSRQQEEWGVTEGSKEEVESYFQDICPKARQLIGLPKSWKRWATADREPIPQWTFGRTTLLGDAAHPTTQYMAQGACMALEDAVTLGEALRVHGNDWGKALDLYQRSRITRTARIVLSGREMGRLYHAQGVERLVRNSLWKGRTTEQFYDAIQWLYGWNVDNCLSESI
What is the function of this protein?
Catalyzes the conversion of 3-hydroxybenzoate to gentisate.
What are the official names of this protein?
3-hydroxybenzoate 6-hydroxylase 2, Inducible 3-hydroxybenzoate 6-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxybenzoate 6-hydroxylase family.
Protein: SPE1_SOYBN
Sequence: MPVLACCVDAAAPPGYAFAGDISFPAPIAFTGVPPATADDTNNSNNHWSPSLSAALYNVDGWGGPYFAVNTAGNISVRPHGSDTVSHQEIDLLKIVKKASDPKSLGGLSLQLPLIARFPDVLKNRLESLQSAFDYAIQSGGYESHYQGVYPVKCNQDRFVVEDIVKFGSPFRFGLEAGSKPELLLAMSCLCKGNPDGLLICNGFKDAEYISLALVANKLALNTVIVVEQEEEVDLIVELSKKLCIKPVIGLRAKLRTKHSGHFGGIFRRRGKFGLTTARVLRVVKNLDLAGMLDCLQLLHFHIGSQIPSTALLADGVGEAAQIYCELVRLGANMRVIDIGGGLGIDYDGSKSCDSDISVEYGLEEYAAAVVHAVQCVCDRSVKHPVICSESGRAIVSHHSVLIFEAVGTSSTNGGGAPPALSAHYLAEELSEDYGYLSELAFRGDYETCLVYTEEMKERCVEQFKQGTVCMEQLAAVEGLCELVRKAVGAAESVRRYHVNLSIFTSVPDAWGIEQVFPIIPIHRLDEKPSVRGILSDLTCDSDGKIDKFINGESSLPLHEMEGGRTYYLGMFLGGAYEEALGGVHNLFGGPSVVRVSQSDGPHSFAVTRAVPGPSCGDVLRVMQHQPELMFETLKHRAQEYVSHDNAAALLAAGLARTFDRMPYLLSLSSFVADDVAAAVPAAQDLGEQWSY
What are the official names of this protein?
Arginine decarboxylase, ADC, ARGDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: COAX_BURCH
Sequence: MSEPHLLIDAGNSRIKWALADARRSLVDTGAFGHTRDGGADPDWSHLPRPRGAWISNVAGADVAARLDALLDARWPGLPRTTIRARPVQCGVTNGYTTPEQLGSDRWAGLIGAHAAFPGEHLLIATFGTATTLEALRADGRFTGGLIAPGWALMMRALGTHTAQLPTLTTDIASGLLAGAQAEPFQIDTPRSLSAGCLYAQAGLIERAWRDLVAAWQAPVRLVLAGGAADDVARALTVAHTRHDALILSGLALIAADAAPATAQD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_ECO8A
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: SYR_MESH2
Sequence: MKKKISQAIIKFFKNENLIIDESKLIIEKSKNFGDYSSNVALIFAKQNKIDSLKLAQTIKNQLLSENLNLEKIEIAPPGFINFFISKNEYANIVSEIIQKGENFGRYSLQKKINLEFVSANPTGFLHLGHLRGAVIGDILANILEFSGNFVFREYYINDFGSQIDRLVGSVFSRYQQIFKKFPLPEEAYLGEDIIWCAQKFFQIYANKFENSSLDDLEAYKIFREKSIEIFLDEIKADLANLSIKFDVFSSESELFRTEKVQKNLANLPFVYKKEEAIWLKTSKFGDQKDRVLVKKNGEFTYFSSDIAYHFEKINSNFKPDFLINIWGADHIGYVDRMKAALKTVNLNQKLDILLYQLVKLFKNGQEFKMSKRMGKTFTIKDLLELVDQDAIRYFISERSYNSLVEFDIGLAAKISLQNPLFLIQYAHARASKLLANSTIAPEKKLKFEAENETILISKLKQFEEIVLKITKNYKINLLNKYLLELANLFNSFYSNSKIIGNQNQNSLLSLTKAVQIVLKNGLKLLGIKAKERI
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX4_PICGU
Sequence: MSNDVYFESIHMQSNYEEFETQAQERENISKISTSLSKFRKMSPKSTRSFKVKSAPLTNRKARNRIKSINAHVSAQYKVSNGQQNDDILDFFLKRKHNISSILEGVEDLENRNIVSNDTPQPSDNTGNYSSQLFTQEEWFQILRRIKLRFPKLSARTRKSLKYVTTKLEHLKNINSDDDSPQLWTQAASLPEEGLVNEDMKWLYELDDEQMDIGSSFCNVDEDSDQKLFVLTLSQAMGEREKSEPDVEIISDSSPEPTQLLNDGIIEEEHEVDEEEEDNENEEKSEKQLASSPTQISSDDTQEQLTNRAEISSYEASSLFPNTLETQKQPVKSTIQKQASVVVPDYPKISNVKDEEIILSSSPTRDNEIFQTPRKYSVESVRSSPSSRSGRLGRLMVSPLKLLSPDRLDASQSVYSTARSSPTKQKRVRGREVNEKIVRKRFKTSRVEVAGNFHLKASDDLKIVSTVDKVNGSEVEDSEDDDHSVSIIEITHEVNDEELKAVDEEVTGEAEDGPSIIQVPSSPGNENLQEDLTSMQTSIASVTQEVPSNYTATQMRQALRSLDFPPERSKEGMASSLTRAASIAGTSVSSLLTPDAPYEEVKNQIYSAISESVKKDQLWHERVLSYEPIVLEEFKQWLGELDKDLKFDVTFLQQYCDHMGITTTIGTTTGTTAGTNTTTTD
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMP_BURO1
Sequence: MQLTELIETTVTGLGYELVELERTGRGMLCIYIDQPAGISLEDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFERFAGSEVSVTLKKPLDGRKTYRGILHAPNGETIGLEFEGKKGEAAMLDFTLADIDKARLIPQVDFRSRK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
Protein: RECO_BRUAB
Sequence: MEWRDEGVILGTRRHGETSAIVEVMTCGHGRHMGMVRGGRSRRMQPLLQPGNHVDVSWWARLDEHMGTFTIEPLSFAAARLIETPVALYGIQLAAAHLRLLPERDPHRGLYETLRLIIEHFDDPLAAGELLLRFEVMMLEELGFGLDLKECAATGRKDDLIYVSPKSGRAVCREAGAPWAEKLLSLPSFVNDTALRASCYDDLDRAFTMTGYFLMRHVWEPRAQTPPDSRSGFLNAVGRAINLSQAS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: MDXF_BACSU
Sequence: MNKHHTLTKQKRKAGLLSIIPGLGQIANQQLSKGLLFLAITGLFAFELCVFGIQALTGLMTLGSVPGEDHSLFMLIEGTLQLIVTMIFLMFYIFNIHDSRKTAAMKAAGLEVNTTAKDMICHAGDKGFPYLFTLPAYIMMVFVIIFPVLVTLFVALTNYDFYHIPPNRLIDWVGFKNFLNIFFLGSYRETFVNVLGWTVIWTICATTLQIILGIVTALFVNQDFIKGKRIFRMIFLFPWAVPAFITIMSFSNMFNDSIGAVNAQVIPLFNHLPFVELPAIAWKTDPFWTKTALIMIQTWLGFPYIYVMVTGVLQAIPGELYEAAKIDGATFIQRFRHITFPMILFATAPVMITQYTFNFNNFSIIYLFNEGGPGSAGAGAGSTDILISWIYKLTTGTSPQYSVAAAVTLLISFIVIGISLIAFKKSNAFGNEEVM
What is the function of this protein?
Part of the ABC transporter complex involved in maltodextrin import.  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Maltodextrin transport system permease protein MdxF.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNLJ_ARTS2
Sequence: MRLEPDNVGDLGQDRSVSTGNTAADTDTQSMTGAGTREADTASERVPSGAVREEYENLVEEVRKHRFAYYQEDAPIISDAEFDELFRRLETIEAMHPELVANDSPTQEVGGEVSAAFAAVEHLQRMYSLEDVFSLEELESWIAKAEASVAKLGNGTAGPAWLTELKIDGLAVNLLYRDGKLVRAATRGDGYTGEDITHNVLTIKEIPQQLTGGNYPAEMEVRGEVFIPSKAFAEYNEALIEAGKAPLANPRNAAAGSLRQKDPAETAKRPLRMYVHGIGAREGLRTVSQSDTYRQLAEWGLPTSPYFEVLGSLKDILDFIKRYGDKRHSLTHEIDGIVVKVDDFATQRALGYTSRVPRWAVAYKYPPEEVHTKLLDIAVNVGRTGRVTPFGIMEPVKVAGSTVGMATLHNQDVVKAKGVKIGDIVVLRKAGDVIPEIVGPVLALRDQQDPPVRDFVMPTECPACGTPLAPGKEGDVDIRCPNSRSCPAQLRERVFHVASRGAFDIEALGWEAAIALTQPAEPVTPPLTSEANLFRLTREDLADVRIRREKRSKGVATGEFELVPYFYTKGTAKSPSKPTATTEKLFTELEKAKSQPLWRVLVALSIRHVGPRASRALATAFGSMDAIREASEEELAHVDGVGPVIAAALKEWFAEDWHREIVDTWAEDGVRMEDEQDESTPRTLEGLTVVVTGSLEGFSRDEAKEAILIRGGKASGSVSKNTSYVVAGENAGTKLDKAEQLGVPVLDEDGFRALLANGPAASADSADASADDDDAGVGDRPEDHQEEPAE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PGK_EXISA
Sequence: MNKQSIRDIDVKGKRVFCRVDFNVPLKDGVIQDETRIQAALPTIKHLLDGGAKLVLASHLGRPKGEKKPEFSLAPVAKRLAELLGKDVPLVEEAYGPVAEEAVANLSEGDVVVLENVRFYPGETKNDPELAKGFAALADVYVNDAFGAAHRAHASTEGIAHHVDTAVAGLLMEKELEVLGKALSNPDRPFTAIIGGSKVADKIGVIDHLLDIVDTLIIGGGLSYTFSKALGHEVGTSLLEEDKLDLARQFMKKAEDKGVKFLMPVDCVITKEFGEETYVGPVDIDSIPADHMGLDIGPKTVELYADAIRESKLVVWNGPMGVFELDKYANGTKGVAQALADSDAYSIIGGGDSAAAAAKFGLADKMSHISTGGGASLEFMEGKKLPGVEALNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_CALS8
Sequence: MKKFKVVSDFKPTGDQPKAIEMLTEGILKGEKFQTLLGVTGSGKTFTMAKVIENVQRPTLVLAHNKTLAAQLCSEFREFFPENAVEFFVSYYDYYQPEAYIPETDTYIEKDSSINDEIDKLRHSATSALFERRDVIIVASVSCIYSLGSPEDYLNLTLSLRPGMIKDRDEVIRELIRMQYERNDIDFRRGRFRVRGDVLEIFPASNTDRAIRVEFFGDEIERITEFDVLTGEVIGRRNHVAIFPASHYVTTSEKLKRAIKSIEEELEQRLQELRSMGKLVEAQRLEQRTRYDIEMLQEMGFCKGIENYSRHLTGRPPGSPPYTLLDYFPKDFIMFIDESHVTIPQVRAMYNGDKARKDALVEYGFRLPSAYDNRPLTFEEFEEKLNQVIFVSATPGPYELKKSSRVVEQIIRPTGLVDPEIEVHPVKGQIDHLIGEIRKRVEKNQRVLITTLTKKMAESLTEYLKDVGIRVRYMHSDIDTIERMQIIRDLRLGKFDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSETSLIQTIGRAARNVDGKVIMYADRITKAMQKAIDETNRRRKIQIEYNQKHGIVPQTVRKGIRQIIEATISVAEEEEKYESIEKDIVQNMSKQEIEEYIKELEQQMKRFAIELEFEKAAKIRDKIFELKKLL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSI1_YEAST
Sequence: MNQCAKDITHEASSIPIDLQERYSHWKKNTKLLYDYLNTNSTKWPSLTCQFFPDLDTTSDEHRILLSSFTSSQKPEDETIYISKISTLGHIKWSSLNNFDMDEMEFKPENSTRFPSKHLVNDISIFFPNGECNRARYLPQNPDIIAGASSDGAIYIFDRTKHGSTRIRQSKISHPFETKLFGSHGVIQDVEAMDTSSADINEATSLAWNLQQEALLLSSHSNGQVQVWDIKQYSHENPIIDLPLVSINSDGTAVNDVTWMPTHDSLFAACTEGNAVSLLDLRTKKEKLQSNREKHDGGVNSCRFNYKNSLILASADSNGRLNLWDIRNMNKSPIATMEHGTSVSTLEWSPNFDTVLATAGQEDGLVKLWDTSCEETIFTHGGHMLGVNDISWDAHDPWLMCSVANDNSVHIWKPAGNLVGHS
What is the function of this protein?
Acts as a component of chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA in vitro.  It performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.  p50 and p60 form complexes with newly synthesized histones H3 and acetylated H4 in cell extracts (By similarity).  Independently, MSI1 is involved in regulation of the RAS/cAMP pathway via sequestration of NPR1.
What are the official names of this protein?
Chromatin assembly factor 1 subunit p50, CAF-1 p50 subunit, IRA1 multicopy suppressor, Protein MSI1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MRAY_YERPS
Sequence: MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMILFSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATELVVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUSB_AERS4
Sequence: MKPSERRKARHCATQAIYQWQMTRANVGDIEEQFKIDQDTKGVDLNYFRDLLFGVALHCNELDKVFAPFLSRPLEEVDMVDKAILRLATYELTRRDDVPPRVVINEAIELAKAFAADDSHKFVNGVLDKVIKTLNKR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MALT_BACTQ
Sequence: MKKAWWKEGVVYQIY
What are the official names of this protein?
Maltase, Alpha-glucosidase I.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: FLGH_XANC8
Sequence: MSRLPSLSSLCLAIACSALLGGCVAAGDVRPFAELAPIVPVVAPVAQPTAGAIYAAGPSLNLYGDRRARDVGDLLTVNLVENTTASSTANTSISKADTVDMSTPTLLGVPLTVNGIDVLRNSTSGDRSFDGKGNTAQSNRMQGSVTVTVMQRLPNGNLVIQGQKNLRLTQGDELVQVQGIVRAADIAPDNSVPSSKVADARIAYGGRGAIAQSNAMGWLSRFFNSRLSPY
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: RL24_VIBA3
Sequence: MAAKIRRNDEVIILAGKDKGKKGKVTKVLTTGKVVVEGINLVKKHQKPVPALGQQGGIVEQEAAIDASNVAVFNAATGKADRIGFRIEDGKKVRFFKSNGETVSN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: EXT2_BOVIN
Sequence: MCASVKYNIRGPALIPRMKTKHRIYYITLFSIVLLGLIATGMFQFWPHSIESSGDWSVEKRTGRDVPLVRLPADSPVPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVGEAGVPVSSTISREYNELLTAISDSDYYTDDVTRACLFVPSIDLLNQNSLRVKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRRYFLLSSQVALHPEYREDLAALQARHGEAVLVLDKCSNLSEGVPAARRRCHQQQAFDYPQVLQEATFCMVLRGARLGQAVLSDVLRAGCVPVIIADSYVLPFSEVLDWKRASVVVPEEKMSDVYSILQSIPRRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEDWNDPPAVKWGSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
What is the function of this protein?
Glycosyltransferase required for the biosynthesis of heparan-sulfate.  The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone.  Appears to be a tumor suppressor.  Required for the exosomal release of SDCBP, CD63 and syndecan.
What are the official names of this protein?
Exostosin-2, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, HS-polymerase, HS-POL, Multiple exostoses protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein. Secreted. Note=The EXT1/EXT2 complex is localized in the Golgi apparatus (By similarity). A soluble form is found in the serum (PubMed:9756849).
Protein: RL30_POLNA
Sequence: MTKEIKVKVQLVRSPIGTQESHRATVRGLGLRGVNSVSELQDTPAVRGMINKISYLVKVI
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: LYSC_PYGNE
Sequence: MKALIILGLVLLSVTVQGKIFERCELARTLKKLGLDGYKGVSLANWVCLAKWESGYNTEATNYNPGDESTDYGIFQINSRYWCNNGKTPGAVDACHISCSALLQNNIADAVACAKRVVSDPQGVRAWVAWRNHCQNKDVSQYVKGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.