PharMolix/UniProtQA huggingface dataset:
Protein: S3TC2_HUMAN
Sequence: MGGCFCIPRERSLTRGPGKETPSKDPTVSSECIASSEYKEKCFLPQNINPDLTLSFCVKSRSRRCVNGPLQEAARRRLWALENEDQEVRMLFKDLSARLVSIQSQRAQFLITFKTMEEIWKFSTYLNLGYVSMCLEHLLFDHKYWLNCILVEDTEIQVSVDDKHLETIYLGLLIQEGHFFCRALCSVTPPAEKEGECLTLCKNELISVKMAEAGSELEGVSLVTGQRGLVLVSALEPLPLPFHQWFLKNYPGSCGLSRKRDWTGSYQIGRGRCKALTGYEPGEKDELNFYQGESIEIIGFVIPGLQWFIGKSTSSGQVGFVPTRNIDPDSYSPMSRNSAFLSDEERCSLLALGSDKQTECSSFLHTLARTDITSVYRLSGFESIQNPPNDLSASQPEGFKEVRPGRAWEEHQAVGSRQSSSSEDSSLEEELLSATSDSYRLPEPDDLDDPELLMDLSTGQEEEAENFAPILAFLDHEGYADHFKSLYDFSFSFLTSSFYSFSEEDEFVAYLEASRKWAKKSHMTWAHARLCFLLGRLSIRKVKLSQARVYFEEAIHILNGAFEDLSLVATLYINLAAIYLKQRLRHKGSALLEKAGALLACLPDRESSAKHELDVVAYVLRQGIVVGSSPLEARACFLAIRLLLSLGRHEEVLPFAERLQLLSGHPPASEAVASVLSFLYDKKYLPHLAVASVQQHGIQSAQGMSLPIWQVHLVLQNTTKLLGFPSPGWGEVSALACPMLRQALAACEELADRSTQRALCLILSKVYLEHRSPDGAIHYLSQALVLGQLLGEQESFESSLCLAWAYLLASQAKKALDVLEPLLCSLKETESLTQRGVIYNLLGLALQGEGRVNRAAKSYLRALNRAQEVGDVHNQAVAMANLGHLSLKSWAQHPARNYLLQAVRLYCELQASKETDMELVQVFLWLAQVLVSGHQLTHGLLCYEMALLFGLRHRHLKSQLQATKSLCHFYSSVSPNPEACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTARSLRRSLTCIKESLRIFIDLGETDKAAEAWLGAGRLHYLMQEDELVELCLQAAIQTALKSEEPLLALKLYEEAGDVFFNGTRHRHHAVEYYRAGAVPLARRLKAVRTELRIFNKLTELQISLEGYEKALEFATLAARLSTVTGDQRQELVAFHRLATVYYSLHMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYYRLGRLTFCQLKDAHDATEYFLLALAAAVLLGDEELQDTIRSRLDNICQSPLWHSRPSGCSSERARWLSGGGLAL
What are the official names of this protein?
SH3 domain and tetratricopeptide repeat-containing protein 2.
Protein: SM30A_STRPU
Sequence: MRGFVYVLVCVLALASFSRAQLPGGGGPVLPGGGPTIGPVNPDPTRTEVCAKFWVQEGNSCYLFDSGAFLRQVAASRPVVVNNENGLFQAAANMYCGQMHPNASLVTVNSLAENNFLYEWAVRMMVEPEPVWIGLHAGPMGQWQWYSGEPVTYTNWERMTAPMAEPGLGAMIFDADIIAQMFNNQVEITPQWVPEQAINDRHALICEYHPSGMTAAAAAATNAPTFPPMATAPPMAATTRGPVMFQNNPRNLVNSLTGGRFGGSLLHEIPRRQRMRPSNYRKNPYFGIQP
What is the function of this protein?
Matrix protein of the sea urchin embryo spicule.  The function of the matrix proteins is to direct crystal growth in certain orientations and inhibit growth in others (By similarity).
What are the official names of this protein?
30 kDa spicule matrix protein alpha, SM30-alpha.
Protein: HARA_THEKO
Sequence: MAELPIAPVDRLIRKAGAERVSEDAAKVLAEYLEEYAIELSKKAVDFARHAGRKTVKAEDIKLAIKA
What is the function of this protein?
Binds and compacts DNA (about 120 base pairs per nucleosome, corresponding to four histone dimers) to form nucleosome-like structures.
What are the official names of this protein?
Archaeal histone A, Archaeal histone A1.
What is the protein family that this protein belongs to?
Belongs to the archaeal histone HMF family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: DF230_PEA
Sequence: MEKKSLACLSFLLLVLFVAQEIVVSEANTCENLAGSYKGVCFGGCDRHCRTQEGAISGRCRDDFRCWCTKNC
What are the official names of this protein?
Defensin-like protein 230, Disease resistance response protein 230.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: DHAT_CITFR
Sequence: MSYRMFDYLVPNVNFFGPNAISVVGERCKLLGGKKALLVTDKGLRAIKDGAVDKTLTHLREAGIDVVVFDGVEPNPKDTNVRDGLEVFRKEHCDIIVTVGGGSPHDCGKGIGIAATHEGDLYSYAGIETLTNPLPPIVAVNTTAGTASEVTRHCVLTNTKTKVKFVIVSWRNLPSVSINDPLLMLGKPAPLTAATGMDALTHAVEAYISKDANPVTDAAAIQAIRLIARNLRQAVALGSNLKARENMAYASLLAGMAFNNANLGYVHAMAHQLGGLYDMPHGVANAVLLPHVARYNLIANPEKFADIAEFMGENTDGLSTMDAAELAIHAIARLSADIGIPQHLRDLGVKEADFPYMAEMALKDGNAFSNPRKGNEKEIAEIFRQAF
What is the function of this protein?
Catalyzes the reduction of 3-hydroxypropanal.  Is considerably less active with glyceraldehyde, propionaldehyde, acetaldehyde, and butyraldehyde.  Also catalyzes the oxidation of various primary, secondary, and tertiary alcohols.  Is most active with substrates containing two primary alcohol groups separated by one or two carbon atoms.  1,3-propanediol is the preferred substrate.
What are the official names of this protein?
1,3-propanediol dehydrogenase, 1,3-propanediol oxidoreductase, 3-hydroxypropionaldehyde reductase.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: CYSG_ECOLU
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEAHRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: SEPF_BACHK
Sequence: MSWSKVKYFFFDTPEEKEAAQYSYEKEQTDMKKQQDPPEQQDVTFPKAQPKQNVVSIETAKQSSKVVLLEPRTYSEAQGIADHLKGRRAVVINLQRMSTDQAVRIVDFLSGTVYAIGGDIQKIGPKTFMCTPENVDIVGAISELFGEEEDTNIKRW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: ARGB_PSEMY
Sequence: MTLERDAAAQVAKVLSEALPYIRRFVGKTLVIKYGGNAMESEELKQGFARDIVLMKAVGINPVVVHGGGPQIGDLLKRLSIESHFIDGMRVTDTATMDVVEMVLGGQVNKSIVNLINQHGGSAIGLTGKDAGLIRAKKLKVTRQTPEMTQPEIIDIGHVGEVTGVNTELLNMLVQGDFIPVIAPIGVGPDGESYNINADLVAGKVAEALKAEKLMLLTNIAGLLDKQGEVLTGLTTEQVDGLIADGTIYGGMLPKIRCALEAVQGGVHSAHIVDGRVPNAVLLEIFTDSGVGTLITNRKRH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_VIBCH
Sequence: MRPDNRAADQVRPIKITRHYTAYAEGSVLVEFGNTKVLCNASIEEGVPRWLKGQGKGWVTAEYGMLPRATHSRTRREATNGKQGGRTMEIQRLIARSLRAVVDLEAMGEIMITVDCDVIQADGGTRTASITGASVALADAFAHLIAKGQLKKNPMKGHVAAVSVGILGEDVLCDLEYVEDSAADTDMNVVMTEEGKMIEIQGTAEGEPFSHEQLLELLAVAKKGIADIVAVQKASLLD
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: Y3766_METPP
Sequence: MVTTKAVGDGGEDRALAYLLRAGLKLVERNYRVAGGPRVRGGEIDLVLRDRDGTLVFVEVRTRATRSHGGAAATVSGVKQQRIVRAARHYLMRFASPPPCRFDVVAIEGEHIAWLRAAFDAS
What are the official names of this protein?
UPF0102 protein Mpe_A3766.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: COGB_PARCM
Sequence: IVGGTEVTPGEIPYQLSFQD
What is the function of this protein?
This enzyme is a serine protease capable of degrading the native triple helix of collagen.
What are the official names of this protein?
Collagenolytic protease 36 kDa B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: ARLY_PSE14
Sequence: MSTDKTNQSWGGRFSEPVDAFVARFTASVTFDQRLYRHDIMGSIAHATMLAKVGVLTDAERDTIVDGLNTIQAEIEAGNFEWRVDLEDVHMNIEARLTDRIGITGKKLHTGRSRNDQVATDIRLWLRDEIDLILSEITRLQQGLLGQAEREAETIMPGFTHLQTAQPVTFGHHMLAWFEMLSRDYERLVDCRKRLNRMPLGSAALAGTTYPIDRELTCKLLGFDVVGGNSLDGVSDRDFAIEFCSAASIAMMHLSRFSEELVLWTSAQFQFIDLPDRFCTGSSIMPQKKNPDVPELVRGKSGRVFGALMGLLTLMKGQPLAYNKDNQEDKEPLFDAADTLRDSLRAFADMIPAIKPRHAIMREAALRGFSTATDLADYLVRRGLPFRDCHEIVGHAVKYGVETGKDLAEMSLEELRQFSNQIEQDVFAVLTLEGSVNARNHIGGTAPEQVRAAVVRGQELLAGR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_HALLT
Sequence: MSLRVTFLGTGGAVPTTERAPSALFVNREGDRLLFDCGEGTQRGMMRFGTGFGIDHLFVSHLHGDHVLGIPGLVQTLGFNDRAEPLTIHCPPGTEDDLHDLVHAVGHDPAFQIRIESVAPGEVALDADGYEVRAFETVHRTKSQGYVLEEDDRPGRFDRPKAEELGVPVGPKFGRLHEGEPVEAEDGSIVEPDQVVGPPRPGRKFVYTADTRPREGTVAVAEDADLLVHDATFADDMEDRARDTAHSTGREAGSVAERAGAKRLALVHISSRYAADASPIRREAREAFDGECLLPDDGDLIEVPFPDADE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: AZOR1_LISIN
Sequence: MTNVLFIKANGLPAERSVSVALYEIFLAEYKKSHPDDNVTELDLFEADLPYYDVTMMSGLHKEVAGETLTPEEKRLADIANGYLDQFLAADKIVMAFPLWNFSIPAQFLTYLFYLNQAGKTFKYTANGPIGLVTDKKIALLNARGGIYSDGPLQSFEMSLNYVKNVLAHFGISEPEMVIVEGHNAKPDQAKDIISAGAKEAAELAKIF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 1, Azo-dye reductase 1, FMN-dependent NADH-azo compound oxidoreductase 1, FMN-dependent NADH-azoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: NUON_ECOUT
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLVGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEPA_DEHMB
Sequence: MSQSSVRNFCIIAHIDHGKSTLADRLIEMTGTLRHDEMCEQVMDSMELERERGITIKAKAIRLRYISKDKQEYRLNLIDTPGHVDFSYEVSRTIAACEGAILVIDATQGIQAQTLANVYLAIEYNLEIIPVINKIDLPGADIPRVMGEIKSVLGYDEDSVLQISAKLGLGVPELLEAIVNKVPAPKGNANQPLRALIFDSHYDPYKGVVAYLRVADGNINKGDDLRLMGQGTEFRVLEAGYFAPAQVAALRLDVGDVGYIATGLKSVGECRVGDTVTLQHGGAIQPLIGYHPAKAMVFAGIYPTQTDDYHELREAMEKLSLNDASLSSEPESSPLLGHGFRCGFLGLLHLDIIVERLEREFNLSLVVTSPGVSLTVTRIGGEAFTVVNPNEMPLPHEIARIEEPWVSVVIITPSKYIGTVMDLVRENYGVYKNTEYLGQLAMSELGQRVQLHYDMPLRSILTTFHDQLKSRTQGYASLDYEFIGYRDANLSKIDVLVNDVPVDAFSRIIPPDKAHEIGEALVKKLKEMIPRQLYQVTLQAAIGSKIVARADISAKRKDVIAKCYGGDITRKRKLLDKQKEGKKKMRQIGKVEVPKEAFLSVLKLQ
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MURA_ACIGI
Sequence: MDKFVIQGGVKLEGEVRISGAKNAALPLLAAMILADTPITLKNVPDLKDVRTLVKLIGGLGITMSYEGETVIANTSTLDNQFAPYELVKTMRASILVLGPLLARYGSAKVSLPGGCAIGSRPVDQHLKALEALGAQIEVEAGYVHAKVDGRLKGGEVIFDMVTVGGTENILTAAVLAEGVTTIRNAAREPEITDLALMLIKMGAKIEGLDTDTLVVTGVESLHGCEYSVVADRIETGSYLAAAAITGGKVKTTHTDPNLLESVLDKFEEMGAEVTRGEDWIELDMLGKRPKAVSFRTLPHPEFPTDMQAQIMAVNAIGRGFATISETIFENRFMHVPELARMGANIQVEGNDAVVTGVEKLSAAPVMATDLRASFSLVLAALAAEGETIIDRIYHIDRGYEDIEAKLQGLGAQIKRVSE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.  Target for the antibiotic phosphomycin.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADPRM_HUMAN
Sequence: MDDKPNPEALSDSSERLFSFGVIADVQFADLEDGFNFQGTRRRYYRHSLLHLQGAIEDWNNESSMPCCVLQLGDIIDGYNAQYNASKKSLELVMDMFKRLKVPVHHTWGNHEFYNFSREYLTHSKLNTKFLEDQIVHHPETMPSEDYYAYHFVPFPKFRFILLDAYDLSVLGVDQSSPKYEQCMKILREHNPNTELNSPQGLSEPQFVQFNGGFSQEQLNWLNEVLTFSDTNQEKVVIVSHLPIYPDASDNVCLAWNYRDALAVIWSHECVVCFFAGHTHDGGYSEDPFGVYHVNLEGVIETAPDSQAFGTVHVYPDKMMLKGRGRVPDRIMNYKKERAFHC
What is the function of this protein?
Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose.  May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity).
What are the official names of this protein?
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase, ADPRibase-Mn, CDP-choline phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the ADPRibase-Mn family.
Protein: RS2_THEAC
Sequence: MDEEMLIPEEEYQKSGVHIGTQVKSSDMKPYIFKIRNDGLYILDVKKTNSKLIVAGKMLARFEPQDILVVAQRQYAFRPVAKFAEVTGATAITGRFNPGTLTNPSLKFYKEVKVIIVTDPLADVQAMKEAVKIGIPIIALCDANNKTDFVDLIIPTNNKGRRSLAVIYWLLAREILKNRGTITSYDQFKYTIDDFEAQI
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: METN_XYLFA
Sequence: MIQFKDSYKHYGANGREVTALQPLNLEIHAGEVFGIIGHSGAGKSTMLRMINRLEEPSGGHLLINGQDITVLDRMGLRALRRQIGMIFQHFNLLSSYTAGNVAFPLKLTGASDAKINARVAELLAWVGLEAHANTYPAQLSGGQKQRVGIARALATRPQILLCDEVTSALDPQTTTTVLQLLARINRELGLTIVLITHEMDVIRRICDRVAVLDTGRLVETGLVTDVFLHPQHPTTRSFVMETEHIDTSALDQDFSLVNGRIVRLTFIGTDTYLPLLGRVARETGVDYNILSGRIDRIKETPYGQLTVALSGGDPVAAQAAFAAAGIHIEELRA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YOFB_CAEEL
Sequence: MFLHLILLAGLAPVVYLWCTPFIACNQTVYGDFSDIEKGMKVILLGRPFQKMDQLIITGEYYNNGSEVMDDAAFTVGLSKGLIMHQLGMDDLEQYLLTTTLGASEERMNISGKLLGRKKDTFLIVEKAKPNVTCADPFTFVIKSQDGYGFAFGSVQSSELKYTAQVALQYPKNEQSQSVFFDGKIKTSKIEL
What are the official names of this protein?
Uncharacterized protein ZK1290.11.
Protein: PYRR_LACLS
Sequence: MARKEIIDEITMKRAITRITYEIIERNKELDKLVLIGIKTRGVYLAKRIQERLQQLEGLEIPFGELDTRPFRDDKQAQEDTTEIDIDITGKDVILVDDVLYTGRTIRAAIDGIVKLGRPARVQLAVLVDRGHRELPIRADYVGKNIPTGHDEEIIVQMSEHDGNDSILIKRED
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: KCNJ4_MOUSE
Sequence: MHGHNRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWWIAFFHGDLEASPSVPAVGGPGGNGGESPNAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQAATLPLDNISYRRESRI
What is the function of this protein?
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by extracellular barium and cesium (By similarity).
What are the official names of this protein?
Inward rectifier potassium channel 4, Inward rectifier K(+) channel Kir2.3, IRK-3, Potassium channel, inwardly rectifying subfamily J member 4.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Note=TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 family members and KCNJ4 internalization.
Protein: RS18_VIBVU
Sequence: MARFFRRRKFCRFTAEGVQEIDYKDVATLKNYITEAGKIVPSRITGTSAKYQRQLARAIKRSRYLALLPYTDKHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: NADD_ECO24
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: CARDS_MYCPN
Sequence: MPNPVRFVYRVDLRSPEEIFEHGFSTLGDVRNFFEHILSTNFGRSYFISTSETPTAAIRFFGSWLREYVPEHPRRAYLYEIRADQHFYNARATGENLLDLMRQRQVVFDSGDREMAQMGIRALRTSFAYQREWFTDGPIAAANVRSAWLVDAVPVEPGHAHHPAGRVVETTRINEPEMHNPHYQELQTQANDQPWLPTPGIATPVHLSIPQAASVADVSEGTSASLSFACPDWSPPSSNGENPLDKCIAEKIDNYNLQSLPQYASSVKELEDTPVYLRGIKTQKTFMLQADPQNNNVFLVEVNPKQKSSFPQTIFFWDVYQRICLKDLTGAQISLSLTAFTTQYAGQLKVHLSVSAVNAVNQKWKMTPQDIAITQFRVSSELLGQTENGLFWNTKSGGSQHDLYVCPLKNPPSDLEELQIIVDECTTHAQFVTMRAASTFFVDVQLGWYWRGYYYTPQLSGWSYQMKTPDGQIFYDLKTSKIFFVQDNQNVFFLHNKLNKQTGYSWDWVEWLKHDMNEDKDENFKWYFSRDDLTIPSVEGLNFRHIRCYADNQQLKVIISGSRWGGWYSTYDKVESNVEDKILVKDGFDRF
What is the function of this protein?
Induces the host NLRP3 inflammasome to release interleukin-1 beta (IL-1 beta); IL-1 beta release requires ADP-ribosylation activity and uptake by host macrophages.  In the host colocalizes with the NLRP3 inflammasome; ADP-ribosylates NLRP3 in vitro (PubMed:25538194).  ADP-ribosylation of NLRP3 may lead to hyperinflammation (Probable).
What are the official names of this protein?
ADP-ribosylating toxin CARDS, ADP-ribosyltransferase CARDS, Community-Acquired Respiratory Distress Syndrome Toxin, CARDX TX.
What is the protein family that this protein belongs to?
Belongs to the bacterial exotoxin subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Note=Surface- associated protein.
Protein: EX7S_THISH
Sequence: MAKKNAPSAPADFEQALGELEALVERMEQGELSLEASLAEFERGIALARQCQQALQAAEQKVRLLSGEGEEVPLDTPDAEDGDGE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.