PharMolix/UniProtQA huggingface dataset:
Protein: MED22_BOVIN
Sequence: MAQQRALPQSKETLLQSYNKRLKDDVKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLIALRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDPDTDSTDCLSAPLLASPEPSAGGPLQAAAPTHSHAGGPGPTEHA
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 22, Mediator complex subunit 22, Surfeit locus protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: OSB2_DICDI
Sequence: MAKTKILNKNNKKEEIIDQEENEVDVKTTCKELSPPTDLEIENLEKLENSGASRLHIVLSFIKKNGIGIGTDLTHFEFASSFLLPHSTHEYYSDNMAREFDILLKSNIDNEIERLLGVFKYILSIKPIIEDSTRSPLRSVNGETKSSNFHVTIIDEQDKSEKIIKDNYYMVETLDQEKAFVGSCIYNKREGVKVHFNTETKTIFNGTNIKLPIIGNIIIRFEKFNEEYTITNPTLYGRYLRGFVEYCGETTITSKNSKYYIKKTNLAKPLIGGNVNMVEAKLLYGDDPNPLFKINGSWSNEMEIINCKTKETKLLYKRPFNYFTKIIPDILPTDSSIVWKDIIVPISKGEKINISKERSKILEYQKKLNWKISQFHLNTDNNIWEPIIYKD
What are the official names of this protein?
Oxysterol-binding protein 2, OSBPb.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
Protein: DEOB_STAAE
Sequence: MTRPFNRVHLIVMDSVGIGEAPDAADFKDEGSHTLRHTLEGFDQTLPNLEKLGLGNIDKLPVVNAVEQPEAYYTKLSEASVGKDTMTGHWEIMGLNIMQPFKVYPNGFPEELIQQIEEMTGRKVVANKPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQIAAHEDIIPLEELYDICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALKPFGKTVLDHLKDGGYDVIAIGKINDIYDGEGVTEAVRTKSNMDGMDQLMKIVKKDFTGISFLNLVDFDALYGHRRDKPGYAQAIKDFDDRLPELFSNLKEDDLVIITADHGNDPTAPGTDHTREYIPVIMYSPKFKGGHALESDTTFSSIGATIADNFNVTLPEFGKSYLKELK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP1_HSPV
Sequence: MNRNPDQNTFPNITLKIIETYLSRVPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFFSDVNTSASEIKDRILSYFSKQTQTYNIGKLFTIIELQSVLVTTYTDILGVLTIKAPNVISSKISYNVTSMEELARDMLNSMNVAIIDKAKVMGRHNVSSLVKNVNKLMEEYLRRHNKSCICYGSYSLYLINPNILYGDIDILQTNSRTFLIDLAFLIKFITGNNIILSKIPYLRNYMVIKDENDNHIIDSFNIRQDTMNVVPKIFIDNIYIVDPTFQLLNMIKMFSQIDRLEDLSKDPEKFNARMATMLEYVRYTHGIVFDGKRNNMPMKCIIDENNRIVTVTTKDYFSFKKCLVYLDENVLSSDILDLNADTSCDFESVTNSVYLIHDNIMYTYFSNTILLSDKGKVHEISARGLCAHILLYQMLTSGEYKQCLSDLLNSMMNRDKIPIYSHTERDKKPGRHGFINIEKDIIVF
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: CYB_LITWA
Sequence: MTNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTADTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFATMATAFMGYVLPWGQMFFWGATVITNLLSAIPYIGTNLVXWILGGFXMDKATLTRFFAXHXILPFMIAALAXMHLXFXXETGSNNPPGISSDADKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILILMPLLHTSKQRSMMFRPISQCLFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPVTSNIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLNE_SALA4
Sequence: MTPLSSPLSQYWQTVVERLPEGFTETSLSVQAKSVLTFSDFALDSVIAHPEWLAELESASPQADEWRHYAGWLQEALAGVCDDASLMRELRLFRRRIMVRIAWAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDLNRARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQVLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLCAASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDPQLTSQFDTVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDEHEAQALTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: LYSK_PYRAE
Sequence: MDVGELLEDVLRIYSPSHGEADLAKYLLEYLKRFVPDVWIDEAGNVIAVKGSGGPVVWLHAHMDTVPGPLPVKREGGVVWGRGAVDDKGPLVAYLKAFLDSNPRGTLVLALVTAEEDDSAGTEALLRGGPPRPDYVFVGEPTNLHIAYAYRGGAKVYIELESRGGHASSPIYDNIVEELFAVYQEVKRALGHAERYDAFTVTPTIIQCGEAPNKVPTKCVMVLDVRIPPGKSCRDLAQALPPKARAGPCTEPVEVSPTNPAARALTRALLKLGVEPKLSRKWGTADFNLLVSLTKNIAAFGPGDPALAHSEDERIDIAQVELAAKALKLAVEELGIIPRRL
What is the function of this protein?
Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
What are the official names of this protein?
Putative [LysW]-lysine/[LysW]-ornithine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. LysK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP050_YEAST
Sequence: MKPIPSYKFRAAEFSTSVSNMISSQCSLCILSMAISTSFFAMPCPRYVDSTASIPIYPLSLTFLCGSILHTMQPMGMLGVPLLLSTAMYVNSGHWFKKYLYTYIEYGSDRSASISFLILANCSSLRMSNGLYTISMS
What are the official names of this protein?
Putative uncharacterized membrane protein YPR050C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LTN1_DICDI
Sequence: MGKDRDKGFRGAKYNPSSSGEANTLMGSQSSGFIGFSAFSSNLTNATDPDYYQVEPEYKVLLKKLQKKDSISRIKGLEELNSKFQKINIEDAEFNISSISPLMNAWEFMYKRLVNDDDRNVRDLASQCLGSIGSRIGKHLGPHVKQLLGPWIVAICDQNDQSINNALLSFQNIFPEKKRKDVFKFGHDEALTYLCENLQETPQTIGDSKSISQEILQERYERCISNSLLAIEYLINNTTATATDSSSSSSTTTTTTTTNNTGNTEIYEKIFESQFFSFFQSKSSNIRKTAYRVLTTVIKKLAGYVEKNFKDFSSKVLGLFSEKDSSTHLYMWDAIISFLQQYGDKAWSNVDVRKHVLPRLWAFLRSGCYGSFELSYPSILPLLTFIPNSIVIGSPSPSPSPSPNTNIDIGFFKELFTNLEKGLEVVDNPRQYGNPNSVDRPSNLLLSCYLECLIYSSKKWGQQYQQINDYLIDTLLFNFYNNHFNLEHSCFSEKLFIEKLLESTIKLANLSNSNLLKIQNLFNSNSFINFNNKENLLNNNEPITTDNNNNNNNNSSPIIKKQEKIIQPISKETLISRLNTFIIVCSNNNNSNNSNNNNVIQVIIKRLFNLACDNLNSNQELSIKILDFILGNYKIDQIISNGLDDIKKIITQLALALNESLLSTGGLNLGVGGDLVSVIVGLLALVPDEDEIKLIWSQILQIFLDSINNNNNNSKKKNNRSNLITNTTNSLVHLINSASNKINRNLLLSTTLFKSIKIQDKKQLQLIKSILFNNNNNNNNEFSPIIPNESVELLIKWVYNKLVDIINTMVQLNLVFNDNDKGGDNNNDDDSDDNDVSIDYLVELSKLLFSSRFKSKSLESLLIEWCKFNIEINNRPSLSGFKSKCNSIDEYLFSTTSNIENDKFILSLLIESIDRNSSTIITNDNLNLNFLSNCAIKLIKSGSYRHDENGDDDDDDDQLYSYFIKEFTSNQLVINSKDQIKISWFRYNRITPFYLLDNYGSNKDNNDSTTFSTDKLLKVLIFNFKVIESFGLEKFIKYSNKENNNSIELLLLNLLFVNGDNQLPPTPTTTTTTTTTITTAVVVSTNEQILEFIENNSTNLLNQFIESLFKFYGDEIFNCNWFNCLVSNVGGDGNNGGIYSVLLALFIDYITSDACLPTSSMKLKSALLNSIKIDNDDNGNSIDSIRQLNLVQILLPILQKESIESYKQWSINQLSQLSSSIPTNFKSISIQLSILSSIVIQRQQQQHQQSQKEQQQITQDDNEILKEKEWLTLLNLIQTIQQWNSKIKSAIIKQQEPELEFLFMKEVELSCLNFILIVIQYISNINSNKSKQPIYLSNNQSQFVQSFLSIWLSNNFTLLSFNKFKSNYYYQQYRNLIEYQSLKIYNIIISNDNIKFIIPGIGDQFQIDHSILILNNWLNRVSNSRSNNNNGNTSDSSYILELYSNTFMKMSNDIKYKISLTKLDNLIELLSTFNYSTSIYNNKGIKKTSYNLLESYFGNENTQLVKSFLLENENNNNNNNNDDGEEKVSFILFSNIFEKILLDFDSTFKPMKKSKDNQLINSISMGQLMCWNLLLLNYSKIDLNRRSILNGWLNDNNIQKVTLFLNQIFPFINKDESPLTTTTTTTDNNGNNYSIEFPFSIIDNDQLITYRMIQKLCSNCFYSLVNYLPSMVRRWADDNSTNSKMNQQIQSYITRFISPIIIQNEIQRVNSYRCTDSDSSDAKFQIKGSTSSKEVTASYEKDEMTISLVLFISDNYPLRVLTVEFSKRVGVSESQWRQWLLSMTSLLLTQDGTVLDACLLWKNSLDKHFQGVEVCPICYSMFHNGTIPKFQCKTCKNKFHAGCIYKWFQTSHKSNCPLCQTDLS
What is the function of this protein?
E3 ubiquitin-protein ligase.  Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.  Ubiquitination leads to cdcD/CDC48 recruitment for extraction and degradation of the incomplete translation product.
What are the official names of this protein?
E3 ubiquitin-protein ligase listerin, RING finger protein 160, RING-type E3 ubiquitin transferase listerin.
What is the protein family that this protein belongs to?
Belongs to the LTN1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RAPA_SALPA
Sequence: MPFTFGQRWISDTESELGLGTVVAMDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHEGWQLHIDEVKEENGLLVYVGTRLDTEETNVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPYSGLRGQRTNLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYTEAQHDAYNPFETEQLVICSLDFARRNKQRLEHLCDAEWDLLVVDEAHHLVWSTDAPSREYMAIEQLAERVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQKNYRPVADAVAMLLAGNKLSNDELNRLGDLIGEQDIEPLLQAANSDRDDAQAARDELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTVKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRAIYDSAYASLINYLAAPEETDGFDDLIKSCREQHEALKAQLEQGRDRLLEIHSNGGEKAQQLAQSIEEQDDDTNLIAFAMNLFDIVGINQDDRGDNLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELVYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLSAVNRHTGSKLVNAVQQDVHAILQLGETQIEKSARALIDNARREADEKLSGELSRLEALRAVNPNIRDDELAAIDSNRQQVLESLNQAGWRLDALRFIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: RLMM_PROMH
Sequence: MNKVALYCRPGFEKECAAEITDKAGQIGVYGFSRVKEGSGYVIFECYQEGDADKIARDVDFRGLIFARQLFVCGELLKNLPPEDRITPIIDQLKGSTEKAGELRVEVADTNESKELLKFCRKFTVPLRNQLRKEKILLKVENYSRPVIHVFFIAPGCCYVGYSYSFNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPYEEWEERLASGMSAVDLGACPGGWTYQLVKRSMMVHAVDNGPMAPSLMETGQVRHHQADGFKFEPTSKNITWLVCDMVEKPAKVAALMTTWIVNEWCREAIFNLKLPMKKRYEEVAHILDKIRAELAEKGINAKIQAKHLYHDREEITVHIQNIWAAYRPDREF
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_AGRRK
Sequence: MSSATDFDPKPRRSSVAVDVGGVIVGGGAPVVVQSMTNTDTADIDSTVAQVAALFKAGSELVRITVDRDESAAAVPKIRERLLRLGMDVPLIGDFHYIGHKLLADHPACAEALAKYRINPGNVGFKDKKDKQFAEIIEMAIRYDKPVRIGVNWGSLDQDLLTALMDQNSAAGSPLSARQVTRETIVQSALISADLAEEIGLPRNRIILSAKVSQVQDLIAVYSMLSERSNHALHLGLTEAGMGSKGIVASSAAMGYVLQHGIGDTVRVSLTPEPNGDRTREVQVAQELLQVMGFRQFVPVVAACPGCGRTTSTVFQELAQNIQNDLRKNMPVWRDKYPGVEALNVAVMGCIVNGPGESKHADIGISLPGTGESPAAPVFIDGQKAMTLRGPNIASDFEALVADYIEKRFGQKSVAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: EPO_PIG
Sequence: MGARECPARLLLLSLLLLPLGLPVLGAPPRLICDSRVLERYILEAKEGENATMGCAESCSFSENITVPDTKVNFYAWKRMEVQQQAMEVWQGLALLSEAILQGQALLANSSQPSEALQLHVDKAVSGLRSLTSLLRALGAQKEAIPLPDASPSSATPLRTFAVDTLCKLFRNYSNFLRGKLTLYTGEACRRRDR
What is the function of this protein?
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass.  Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
What are the official names of this protein?
Erythropoietin.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURL_NITWN
Sequence: MIVRNEPPITPELVASHGLKPDEYERILKLLGRTPTFTELGIFSAMWNEHCSYKSSRIHLRGLPTKAPWVIQGPGENAGVIDIGDGQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARPIACLNALSFGDPSHPKTRHLVSGVVAGVGGYGNSFGVPTVGGQVRFHTRYDGNILVNAMAVGLADADRIFYAAASGVNMPIVYLGSKTGRDGIHGATMASAEFDDDSEEKRPTVQVGDPFAEKLLLEACLEIMAKGCVVAIQDMGAAGLTCSAVEMGAKGDLGVDLDLDSVPTRETGMSAYEMMLSESQERMLMVLKPEKEKEAEAIFRKWGLDFAIVGSTTPGRRFVVRHGGDVMADLPIKELESEAPLYDRPHVPSPQLPVIQARDVAPSLTTADALEKLLAMPELCSKRWVWEQYDHVIGGNTVQRPGGDAAVVRVEDGPKGLALTVDVTPRYCEADPFEGGKQAVAEAWRNITAVGGRPLAITDNLNFGNPERPENMGQFVGCLKGIAAACTALDFPVVSGNVSLYNETNGRGILPTPTIGGVGLLDDFTKSASLAFKAEGHPILLIGDTQGWLGQSVYLRDICRREEGAPPPVDLAAEKRNGDVVRGMIHAGTATAVHDVSDGGLLVALAEMAMADGIGAALDAAPAAIVPYAWWFGEDQARYIVTVHERDLLSVFTKLKAVNVPCIQIGLTGGHEIAIAGERAVDLKVLRQGFESWLPDYMAGKP
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_EHRRG
Sequence: MFNLIRKSTEWGGKTLVLESGKIARQANGAVVVTYGGTTVLSTVVAGKAKEPVDFLPLTVQFVAKSYAVGKIPGGFLKREGKPSDRETLISRLIDRSIRPLFPSGFYDEVSIVCNLLSYDTVTPPEVTALIGATAALAISGVPFNGMVVGARVGYLLSEDKYLLNASADEMLSSSLDLFLSGNKDSVLMVESEASELSESQMLAAISFGHQNCQEVIKLIEEFREESGILPFGFIPHDITSLVDDIASSYTESFSIAYSNIVKKERVLELEKLRDQVLSDMLAKYEQPNGNLQCQYSSQDIISALKSFERSLVRSKIIETSSRIDGRAFNGIRDIEIEIDVLPKTHGSALFTRGNTQALVVTALGTPQDEQIVDDLDGDRRENFLLHYNFPPYAVGESAALRAPGRREIGHGKLAWKAIRYVLPEKSDFPYTIRVVSEITESDGSSSMATVCGASLALMDTGVPIKAPVAGIAMGLIKEGEKFIILSDILGDEDHLGDMDFKVAGTSSGITALQMDMKISGISIEVIEKSLLQAKDGRMHILDKMNLVIQESRECIKNHAPRIESIFINKDKIRNVIGSGGKNIREICEKTGARVEIMQDGTVMIYAINNDAVEYAKNMIMDIVSEPEIGKVFDGTVIEIVKFGAFVSFLGGKRGLIHISEIKNEHINAVGSVISVNDKVKVLVIGIDREYVQLSMRRVDQETGEPIDGELYNIRKTNSDSDDSFLSSGSVNNRHGSEKKRRGSGRSRRSSGGSSYHRDDLHNNGFGNGNRSFNDNRNGNEVPRKPRFF
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4066_RHIME
Sequence: MFVRVMSREECQGVVAAGDLARLACCRDDQPYIVPITYAHSGNRLYCFSMPGQKIDWMRSNPKVSLQIAEFASNRQWKSVVVTGRYQELPATQGCHHERIHAWSLLEKKPNWWEPGGLKPVPQEISGASAHIFFCVEMDEMTGRAACAGEL
What are the official names of this protein?
Uncharacterized protein RA0666.
Protein: RL14_PORG3
Sequence: MIQQESRLVVADNSGAKEALCIRVLGGTRRRYASVGDIIVVSVKSVIPSSDIKKGAVSKAVIVRTKKEVRRPDGSYIRFDDNACVLLNAAGDIRGSRIFGPVARELRGTNMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DNAA_STAAU
Sequence: MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLSSIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKETTKPSTETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLIDDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLLGKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEIRNV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXB6_HUMAN
Sequence: MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B6, Homeobox protein Hox-2.2, Homeobox protein Hox-2B, Homeobox protein Hu-2.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYO1H_MOUSE
Sequence: MEGALTARDKVGVQDFVLLDAYTSESAFLENLRKRFRENLIYTYIGTLLVSVNPYQELGIYTASQMELYQGVNFFELPPHVYAIADNAYRMMCSELNNHFILISGESGAGKTEASKKILQYFAVTCPMTESLQIARDRLLLSIPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFQGVPVGGHIISYLIEKSRVVYQNHGERNFHIFYQLLAGGGSERLASLGLERDPQLYKYLSQGHCARESPISDKNDWETVCGAFSVIGFTEADLENLFGIIASVLHLGNVCFKGDKQGCASVPDTHEIKWIAKLLGVCPAVLLEALTHRKIEAKTEEVICPLTVELSVYARDAMAKAVYGRTFTWLVNRINSSLVNKDFTQKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYESEGIEWETVQYFNNKIICDLVEERHRGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFQTRKLAGPKGRKRIGWLEFCLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCSSKNSILRECFLVAELENRRRPPTVGTQFKNSLSSLLEILISKEPSYIRCIKPNERKEPSKFDDFLISHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPGEGVERLIKYIGYQPQDYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVSRIQATYKGCLGRREYMKKRQAATKLEAHWRGVLARKEIKRRRWAVQIIRRFVKGFINRDKPLCPDNEEFVVLVRKNYILNLRYHVPKNVLDKSWLRPPGILENASNLLRRMCTRNLVRKYCRGISAERKAMMQQKVVTSEIFRGKKEGYAESLNQLFAGSRLGVSTSSLSDGILVIHISPADKQQKGDVILQCEHIFEVATKLAMLIRKEHTVRVVQGSLQFYVSPGREGTIVFETGEEDQVYKDKNGQLRVVSAGKKT
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
What are the official names of this protein?
Unconventional myosin-Ih.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: TRPB_ELUMP
Sequence: MTMLNPKKQISKPNTLIPNEHGFYGIYGGVFVPKELIVPLAEIADCFNNTAFTKEFQDELFYYYKNYVGRPSPLYYAANISCGGAKIYLKREDLNHTGAHKINHCIGEVLLAKKMGKKRVIAETGAGQHGIAIATAAALLGIECVIYMGEQDVKKEYPNVLKIKTLGAKVVCVGSGAKGLKEAVDAAFDDYLKDPETQMYAIGSVVGPHPFPLMVASFQSIVGKEAREQFLEQEGRLPDNVVACVGGGSNSMGIFSGFFADKTVKLTGVEPAGKGLETGLHAAPLAKGRVGVVHGFKCYFMQDDKGNPMGTHSVASGLDYLGVGPQHCYLKDSGRVTYRSACDDEAVDAFFMLSRKEGIIPALESAHAVAYALKLSKELGKDKSILVNLSGRGEKDLDYVLSLYGKKYGVDI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: KAS2_STRCN
Sequence: MNGSGSGIRTRRTAVTGIGVVAPNGLHADTYWKSVKEGASVLDRITREGCEHLPLRVAGEVRGFDPSALIEETFLVQTDLFTHFALAAADAALQDAGLTKAAAVADSPYSVGVVTAAGSGGGEFGQRELQKLWGQGSRFVGPYQSIAWFYAASTGQISIRSGFKGPCGVVASDEAGGLDAVAHAARVVERGTDVVVVGAAEAPLAPYSMVCQLGYPELSTDEDPAIAYRPFTSAARGFVPAEGGAVLIVEEADRAHRRGAVVRATVAGHAATFTGASHWDQSREGLAHAIHGALDEAGCAPEEIDVVFADAMGVPEADRAEALALVDALGRHAPRVPVTAPKTGIGRSYCGAALLDIAAGAGMEHGQIPPTPNVFDICHQIDLVTATARPASSAPLVLSRGLMGSNAALVLRPGPGSTA
What are the official names of this protein?
Putative polyketide beta-ketoacyl synthase 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Protein: Y1383_SODGM
Sequence: MPIMASTLYRDMLNFFRNQFASILLLALLTALISVVLGHALSPGSEQLMTLSDGTHLGDTAEMSLQQLVQQMSVEQQRVLLKASAAGTLAGLVGNVLLAGGLLTMIRQVSNRQPVSVLRAIGLSAPLLPRLLLLIFLTTLLVQLGLLLIIVPGILLAIAFSLAPVIATSDDLGAIKSMRQSSSLAFANLRLLAPAVLFWLLAKAAVLLLATQFTLVSSLVAVVLLNGLSNLISALLLIYLYRLYMLLRQA
What are the official names of this protein?
UPF0259 membrane protein SG1383.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.