PharMolix/UniProtQA huggingface dataset:
Protein: AAPA1_HELPY
Sequence: MATKHGKNSWKTLYLKISFLGCKVVVLLKR
What is the function of this protein?
May be involved in response to oxidative stress (Probable).  Toxic component of a type I toxin-antitoxin (TA) system.  When overexpression is induced in situ in the absence of its cognate antisense RNA antitoxin IsoA1 it leads to cell growth arrest and cell death without lysis.  Neutralized by IsoA1 RNA which forms an extensive duplex with the mRNA (PubMed:28077560, PubMed:33229580, PubMed:31476357).  Binds artificial prokaryotic and eukaryotic lipid membranes, with 30-fold higher affinity for prokaryotic membranes.  Molecular dynamics suggests the peptide penetrates the membrane leading to lipid reorganization and thinning of the bilayer (PubMed:31476357).  Induction of toxin in the absence of antitoxin RNA causes a fast conversion of cells from spiral-shaped to coccoid forms; cells have no visible membrane defects and resemble wild-type 'aging coccoids'.  Toxin causes a moderate decrease in membrane potential and ATP content and alterations in peptidoglycan muropeptide abundance; GlcNAc-MurNAc dipeptides increase while GlcNAc-MurNAc tripeptides decrease (i. e.  a faster phenocopy of cell aging).  Deletion of all 6 AapA/IsoA TA loci in strain B128 leads to slower than wild-type conversion of H2O2-treated cells to the coccoid form.  This suggests oxidative stress triggers coccoid transformation via these type I TA systems, although other factors eventually drive the morphology change (PubMed:33229580).
What are the official names of this protein?
Toxic protein AapA1.
What is the protein family that this protein belongs to?
Belongs to the AapA toxin family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: Y542_SYNS9
Sequence: MAGHSKWSQIKRTKAVVDSKRGALFTRLGREIMVAARAGSDPAGNFQLRTAINKARAAAMPASNIDRAIAKGSGQGGEGAQLEDVRYEGYGPGGMAVMVEALTDNRNRTAADLRLAFSKNGGNLGENGCVAYLFEHRSEVSIKTEAGSEERLLESLLDLDADGYELNDETTATIFGPFAGLEALQDGLRQQGWDVKEWGHQWATTTNVSISDPATAQSCLNLLDALESLDDVRSVSANLELDTKLEIN
What are the official names of this protein?
Probable transcriptional regulatory protein Syncc9902_0542.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP24_EBOSU
Sequence: MAKATGRYNLVTPKRELEQGVVFSDLCNFLVTPTVQGWKVYWAGLEFDVNQKGITLLNRLKVNDFAPAWAMTRNLFPHLFKNQQSEVQTPIWALRVILAAGILDQLMDHSLIEPLSGALNLIADWLLTTSTNHFNMRTQRVKDQLSMRMLSLIRSNIINFINKLETLHVVNYKGLLSSVEIGTPSYAIIITRTNMGYLVEVQEPDKSAMDIRHPGPVKFSLLHESTLKPVATPKPSSITSLIMEFNSSLAI
What is the function of this protein?
Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways.  Blocks the IFN-induced nuclear accumulation of host phosphorylated STAT1, by interacting with the STAT1-binding region of host importin alpha-1/KPNA1 protein, thereby inhibiting the latter.  Without the activity of this protein, activated STAT1 would not enter the nucleus and be unable to activate IFN-induced genes.  Plays a role in assembly of viral nucleocapsid and virion budding.  May act as a minor matrix protein that plays a role in assembly of viral nucleocapsid and virion budding.
What are the official names of this protein?
Membrane-associated protein VP24, Reston VP24, rVP24.
What is the protein family that this protein belongs to?
Belongs to the filoviridae membrane-associated protein VP24 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein. Note=In virion, localizes on the intravirional side of the membrane. In the host cell, it is found associated with virus-induced membrane proliferation foci and to the plasma membrane where budding takes place (By similarity).
Protein: NPTN_MOUSE
Sequence: MSGSSLPGALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRESLLPVTLQCNLTSSSHTLMYSYWTRNGVELTATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDAMMYCKSVGYPHPEWIWRKKENGVFEEISNSSGRFFITNKENYTELSIVNLQITEDPGEYECNATNSIGSASVSTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLRQRNTN
What is the function of this protein?
Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK.  May also regulate neurite outgrowth by activating the FGFR1 signaling pathway.  May play a role in synaptic plasticity (By similarity).  Also acts as a chaperone for ATP2B1; stabilizes ATP2B1 and increases its ATPase activity.  Promotes localization of XKR8 at the cell membrane (By similarity).
What are the official names of this protein?
Neuroplastin, Stromal cell-derived receptor 1, SDR-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Postsynaptic density.
Protein: KRB2_VACCC
Sequence: MESFKYCFDNDGKKWIIGNTLYSGNSILYKVRKNFTSSFYNYVMKIDHKSHKPLLSEIRFYISVLDPLTIDNWTRERGIKYLAIPDLYGIGETDDYMFFVIKNLGRVFAPKDTESVFEACVTMINTLEFIHSRGFTHGKIEPRNILIRNKRLSLIDYSRTNKLYKSGNSHIDYNEDMITSGNINYMCVDNHLGATVSRRGDLEMLGYCMIEWFGGKLPWKNESSIKVIKQKKEYKKFIATFFEDCFPEGNEPLELVRYIELVYTLDYSQTPNYDRLRRLFIQD
What is the function of this protein?
Pseudokinase that plays a role in viral DNA replication repression by activating the antiviral protein BANF1 and inhibiting the activity of host VRK1, a cellular modulator of BANF1.
What are the official names of this protein?
Pseudokinase OPG198.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Host nucleus.
Protein: YRS8_CAEEL
Sequence: MFKAYLMAEEQNEQVRDILLLPTTVNDQVGSSADEQIASVVDFFHSKLAEYNEVIQQNSRSVFVANYVQNRFLVTEFCPELAKLFDVLKVKSLEELLQRLTEWEDDPAMKASGKALRESFEAWDIFLREIDDELEKTLGPVKSAVTTLPEDSGILGLQSKTISYYVTGSAFDCVLIIVVRAFNRPEVNEHILGLYNRIDELRKLRCDVFLLTKGPPIGSSGGAYIKLIGVPFRKLYDMNEAEEQLKMNRKSALEYNGWRTLCKVVEASLVEGDSIVAKEASSSEDSVSYISQKGGTVLVDKSGEILYKHIEDDKSDSWPDIDEIVKLVEARNAKYLESTNNSTISIPKGGNLAKVNSEISVTKELATDKKKPCCVIS
What are the official names of this protein?
Uncharacterized protein T05H10.8.
Protein: SYFB_DICD3
Sequence: MKFSELWLREWVNPAISSDALSEQITMAGLEVDGVEPVAGAFHGVVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLKVAVATVGAVLPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEISVTPNRADCLGILGVARDVAVLNELALTAPATEPVTATIADRFPIQVDATEACPRYLGRVVKGINVKAATPLWMREKLRRCGIRSIDPVVDVTNYVLLELGQPMHAFDLNRLEGGIVVRMAKEGETLRLLDGTDATLSADTLVIADHQKALAMGGIFGGEHSGVNGETQDVLLECAYFNPLSITGRARRYGLHTDASHRYERGVDPALQHQAMERATRLLLDICGGEAGPVVEAVSEKDLPARATIALRRDKLDRLIGHVISDEKVSDILNRLGCQVTQTADGWQAVAPSWRFDMAIEEDLVEEVARVYGYNNIPNIPTQAPLKMTQHREADLALKRVKTLLVDHGFQEAITYSFVDPKIQSLIHPGEDALILPSPISVEMSAMRLSLWSGLLGAVVHNQNRQQSRLRLFESGLRFVPDQRADLGVRQETMLAGVITGTRYEEHWDLARQAVDFYDLKGDLEAVLALTGKLSVLEFRAESHPALHPGQTAAIYLAGERIGYIGVIHPELERKLDLNGRTVVFEVLWDKLAERVVPEAADISRFPANRRDIAVVVAESVPAGDVLAECKKVGANQLVGVNLFDVYRGKGVAEGYKSLAISLVLQDTARTLAEEEIAATVAQCVAALKQRFQASLRD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDO2_ARATH
Sequence: MESDLIDLFEGAKKAADAAALDGVTSSGPEVSQCIDALKQLKKFPVTYDTLVATQVGKKLRSLAKHPVEDIKSVATDLLEIWKKVVIEETAKAKKTEGTNGCKEAKVNKMDVEKPSNPAPVKVQKLQRGDSAKSIKVERKEPDNKVVTGVKIERKVPDIKVTNGTKIDYRGQAVKDEKVSKDNQSSMKAPAKAANAPPKLTAMLKCNDPVRDKIRELLVEALCRVAGEADDYERESVNASDPLRVAVSVESLMFEKLGRSTGAQKLKYRSIMFNLRDSNNPDLRRRVLTGEISPEKLITLSAEDMASDKRKQENNQIKEKALFDCERGLAAKASTDQFKCGRCGQRKCTYYQMQTRSADEPMTTYVTCVNCDNHWKFC
What is the function of this protein?
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites (Probable).  Involved in the control of seed dormancy and germination (PubMed:19150360, PubMed:21799800).
What are the official names of this protein?
Transcription elongation factor TFIIS, Protein REDUCED DORMANCY 2.
Protein: RECF_BACMK
Sequence: MFITEIQLKNYRNYEHLELSFEDKVNVIIGENAQGKTNLMEAIYVLAMAKSHRTSNDRELIRWDEDYGNIKGRLQRRNSSISLELNISKKGKKAKLNQLEQQKLSQYIGEMNVVMFAPEDLNLVKGSPQVRRRFLDMELGQIAPVYLYELSQYQKVLTQRNHLLKKMQGNSKNEETMLDVFTLQLIEHGAKILRKRFEFLHLLQEWAAPIHRGISRGLEELEIVYKPSVDVSESMDLSKIKEVYYESFQSVKQREIFRGTTLLGPHRDDLQFFVNSKNVQVFGSQGQQRTTALSLKLAEIELIYSEVKEYPILLLDDVLSELDDYRQSHLLNTIQGKVQTFVTTTSVEGIEHETLKEAKTIHVTNGTVDCEIDRK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFH_PSEPF
Sequence: MVEPVIEIEVVYAAVDRQVLRVISVAEGTTVRAALMASGIDAEFPELDLISCPLGIFGKVIADPDARRVQEGDRIEIYRPLLADPKEVRRLRAAKAAEAKARNQ
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: PPR3C_XENTR
Sequence: MPGDFSVCVCISPPPQPQFHCSPADSLRPCLVPTRRPPDPRKKNVVFADALGLALTSVRHFTRAFFDEEPLVLALASLRALRPLSSPTYTLDFSPPTQDYGRYREQLTRKLVCLEQCAVQGAAVAGTVRVRNVGYEKRVTLRVSYDGWCNHYDLPCTYLFDTRRGGDTDSFSFRMPLPVGTERAEFCICYWCAGEEYWDNNDGKNYSLHKEGKGKGYLQGPYW
What is the function of this protein?
Acts as a glycogen-targeting subunit for PP1 and regulates its activity.  Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 3C.
Protein: UTS1_CATCO
Sequence: NDDPPISIDLTFHLLRNMIEMARIENEREQAGLNRKYLDEV
What is the function of this protein?
Urotensin is found in the teleost caudal neurosecretory system.  It has a suggested role in osmoregulation and as a corticotropin-releasing factor.
What are the official names of this protein?
Urotensin-1, Urotensin I.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDE6_DICDI
Sequence: MNSKYGDNIIDFLRYLEKFVKSLTKDNKIEEFKTFDIKSLLYPRNKDYFGNLSKFLLAVISARIGSNFINEDDIFEISELLKEFLGQELEHLPYLSYEELYVEIVEQVGEINGTVSEIIEAITVTIDFLDTFEKVSQTIDRSNEKQKLLAYLSAPVNQLDNSVSGVFNENDYTDIQRFFTELTNENNQSPDSNISILINDFQSLLNILESQQASSSSSKMIINDSPRTQQRNGTTEQQKKQQQQQYLQKNKEPFYSKDKIMQVSGPSYVFTPSDCNVSIQVGIPPDTLKRDQSICHFIVPHFLISKDVSLSEVEFPIFYNKFVQKGKTKVVIICTVEQKQRIETILCESIFGPAPEHIYTDEEITIPDYKIDLLTERLAIDPRANDEKLDSYVIFKTFDTFGVVDIDLPSASDPTKLINLRIRNTKGLISFHEDYHVVQKQLHLKLQEQQQDQQDKSSSSTTDKQMINTSGNRIILKNNTVSVIDSTIESQYVPVLPFGNDHEQVKKFKAPILGVTFLGVSHGLDFTHCSHTTGFIIWINGSGVVVDPPVGNTTYLQTNGIYGKTVEHIILTHCHADHDSGILQKIIERNKVTLYTTKTINESYMRKLKALTGLPEQSLKNYYTWVPVTIGNKIKILGAEFEFDYSFHVIPTIRFKLEIYNKKISYSADTFYDLQKFKQLKDQGVLSKKRIERLKSFVFDADMIIHESGVAPIHTPMANLLELPSEIRKKIRVVHCSSSVDTKGEIIRPKEGLENTEIIKVDRKYKGVAECIQIQTALNHCSVFSKLSPAEVQRVFFLCKKIWVKRNDVIIKKGSPSDMFYIILSGKVLVYENEYEPIKSTTSVGTVVTDTTTITTTVKTDAIKIPTIKLCAGETLGESALQLDKNIDASATVIAETDVCLLVWKTMDLRTEFHSNLNTFISKVHMDLSHINSCRDAIIRAFQHNITQHINKEEVDSIANGSKDVSFAHHQVIFNEGDTSDSMYIIKQGRVRIHSKKNKNIIRYLNVGDFFGETAYRRSNEDSNFLPTRSFTATAIDPTILLKLDIESIVNPRIQNIIEQKAKKNAEDNIRYHAYSPKIRTPRTPRKVYPIEGLSI
What is the function of this protein?
Dual specificity cAMP and cGMP phosphodiesterase with marked preference for cyclic AMP, which is activated by cAMP and cGMP.  Likely functions as a cAMP-stimulated cAMP-phosphodiesterase which may play a role in regulating the cAMP relay response.
What are the official names of this protein?
cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase B, Cyclic GMP-binding protein B, Phosphodiesterase 6, DdPDE6, Phosphodiesterase E, PdeE.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. cNMP phosphodiesterase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ASNA_KLEP3
Sequence: MKTAYIAKQRQISFVKSHFSRQLEEKLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKTLPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLTPIHSVYVDQWDWERVMGDEERHVGTLKATVEAIYAGIKATELAVSQEFGLKPFLPEQIHFVHSQELLSRYPDLDAKGRERAIAKELGAVFLIGIGGKLSNGKRHDVRAPDYDDWSTEVSEGFAGLNGDILVWNPVLEDAFEISSMGIRVDAEALKRQLAVTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLDHIGQVQCGVWPAQVRESVSALL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBHT_ECOL6
Sequence: MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVTNPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENKHNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAWGGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKNRPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQFCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSAGAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE
What is the function of this protein?
This is one of three E. coli hydrogenases synthesized in response to different physiological conditions.  HYD2 is involved in hydrogen uptake.
What are the official names of this protein?
Hydrogenase-2 small chain, HYD2, Membrane-bound hydrogenase 2 small subunit, NiFe hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Periplasmic side. Periplasm.
Protein: C7111_SOLLC
Sequence: MASIWGLLSPWIPYFISFIAFLLLLEQISYIKKKRFLPGPTLVFPFLGNVIPLVTNPTKFWDLQSALAKSTSHGFSVNYIIGKFILYIHSTDLSHKVFANVRPDAFHLIGHPFGKKLFGEHNLIYMFGQEHKDLRRRIAPNFTPKALGTYTDIQQRIIIKHFKSWLDEASKSPNTPIPLRLLCRDMNLDTSQTVFVGPYLDGESRKRFNVDYNYFNVGLRKLPVDLPGFAFRNARLAVGRLVDTLSVCVEQSLNKMKNEEEPTCLIDFWMQENLREINEAKINGLQKPFQYSNKELGGYLFDFLFAAQDASTSALLWAIVLLDSHPQVLEKVRSDVARFWSPESEEPLTAEMLTEMKYLEAVAREIIRIRAPATMVPHIAGEEFRLTEDYVIPKGTIVFPSVFDSSFQGFPEPEKFEPDRFMEERQEERVYKKNFLALGAGPHACVGQKYAINHLMLIIAMFTALIDFKRHKTDGCDDISYIPTIAPKDDCKVFLAHRCTR
What is the function of this protein?
Required to form the C-22 double bond in the sterol side chain.  Possesses in vitro C-22 desaturase activity toward beta-sitosterol to produce stigmasterol.  No activity with 24-epi-campesterol.
What are the official names of this protein?
Cytochrome P450 710A11, C-22 sterol desaturase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TSGA_SHISS
Sequence: MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSTAMFILGVVSGITMSIGTFLITQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSIEWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCYILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTVLAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVLTCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTSH
What are the official names of this protein?
Protein TsgA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TX112_LYCSI
Sequence: MMKVLVVVALLPTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1b, Toxin-like structure LSTX-A12.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HACL1_ORYSJ
Sequence: MNVGQAAHLSGQMSGQAPQTNQVGGSGVGGADGLPQQMQDVVGLGGLDTQFLLMRNTMRDRIFEYIGRKQSSTDWRRRLPELAKRLEEILYRKFLNKADYLNMMRGPVEPQLQFAIKTLSAQNQQNQQNQQMPRQMASSSGYGTMIPTPGITQSATGNSRMPYVTDNTGLPSSGATMVPQGANTGSMSNGYQHLTTSVPLNSTTSSIPSTMGPVGIQRQVTHMIPTPGFNNQQNVPVNPDFSNGAGYFNGEPTVTSQMQQQKQFPSNQNSHQIQHIGGHSNSGMHSNMLENSSAYGLSDGHVNGGMGVHGSNMQLTNRSAASEAYINISTYGNSPKPVQQQFNQHPPQRIPTPVDISGSGNFYNTGSSALTAANNHSMGATNLPSRSRMNSMLHTNQLNMQSIQPQPQIKTEVLDQPEKMNFQSSQLTHEQLIRQQHSMQQHQMQPSSQFVQNQYHLNQQQPNSQHQQSILRSNSLKQPQLSSSHSMQLSEQGALPHTELISSQATEHADIPIYQGQYQQRSAHDNVKGGQVFGHLSSSQNFHSNASHDSQQLLPTNQQLDDSSNDVSYVLKGSQPEQMHQAQWRPQTMEKAPVTNDSSLEKQIQADLCQRTMSQDGAQQPFSSDWRLPGCTVTPADPALPKLPSGGLEQAAGNIYYFRQMKWLLLLFHAKSCLTPVGSCKFHRCFQVQELVKHFENCKRKDCSYRDCRRSRMVTEHYKACVDLQCPVCSNAKKLLQRSAELASKQKPPEPRKIAQQNTAQRIMNGVEGDIMDIDLVSDEIFDSQPSVPKRLKMQPVSPSTAEREVSMPSNAGLILQETHSELPDQNNKVGQLKMDVKIDPRPLQKPAKIGYGTDGNVPTARHNVAPGGSNEIKTHVKQEIMPIDKETSETAPEVKNEANDSTDITVSKSGKPKIKGVSMTELFTPEQIQEHINSLRLWVGQSKAKAEKNQLMGHNENENSCQLCKVEKLTFEPPPIYCSPCGARIKRNAPYYTVGTGDTRHFFCIPCYNESRGDTIEVEGQNFLKARFEKKRNDEETEEWWVQCDKCECWQHQICALFNGRRNDGGQAEYTCPNCYVEEVKRGLRMPLPQSAVLGAKDLPRTVLSDHIEDRLFKRLKQERQDRAAQERKSIEEVPGAEGLVVRVVSSVDKKLEVKPRFLEIFQEDNYPTEFPYKSKAVLLFQKIEGVEVCLFGMYVQEFGAECSYPNQRRVYLSYLDSVKYFRPEIRTVSGEALRTFVYHEILIGYLEYCKQRGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLSMLRKATKEEIVVELTNLYDHFFITMGECKAKVTASRLPYFDGDYWPGAAEDMINQLRQEEDDRKQQKKGKTKKIITKRALKAAGHTDLSGNASKDAMLMHKLGETIYPMKEDFIMVHLQYSCSHCCTLMVSGKRWVCHQCRSFYICDKCYDAEQQLEDRERHPSNSRDTHTLHPVDIVGLPKDTKDRDDILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNVCCHDIETGQGWRCEVCPDFDLRKMLDLLVHASTCRSGSCQYPNCRKVKGLFRHGMQCKTRASGGCVLCKKMWYMLQLHARACRDSGCNVPRCRDLKEHLRRLQQQSDSRRRAAVNEMMRQRAAEVAANE
What is the function of this protein?
Acetyltransferase enzyme.  Acetylates histones, giving a specific tag for transcriptional activation.
What are the official names of this protein?
Probable histone acetyltransferase HAC-like 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SMG_ALKEH
Sequence: MKQSIFEVLIYLFENYLANDDEPSPDRDSLESELFEAGFTPLEIRKAFDWLDGLADSRNMPATVTGDRAIRVYHERETVRLDVESRGFILFLEQAGILDRAGRELVIDRLMALEDDDVDLDTVKWVVLMVLFNQPGQEEAFNWMEDLLFDNPVHLVH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: XPT_LACJO
Sequence: MKLLEERIRKDGEVLDGNVLKINSFLNHQVDPQLMMEVGKEFKRLFENEKITKVLTCEASGIAPGIMAAYQLGVPMVFARKKKPSTLNDAVYWADVFSYTKKVNNKICVEKKFLSSDDHLLIIDDFLAHGEAVKGMLNIADQANATVAGVGVVVAKEFQGGSEWVKDHGYSLEALARISDFENNQVHFVGEE
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_BACC0
Sequence: MSKIIGIDLGTTNSCVAVMEGGEPKVIPNPEGNRTTPSVVAFKNEERQVGEVAKRQAITNPNTIMSVKRHMGTDYKVEVEGKDYTPQEISAIILQNLKASAEAYLGETVTKAVITVPAYFNDAERQATKDAGRIAGLEVERIINEPTAAALAYGLEKQDEEQKILVYDLGGGTFDVSILELADGTFEVISTAGDNRLGGDDFDQVIIDHLVAEFKKENNIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFISAGAAGPLHLELTLTRAKFEELSAGLVERTLEPTRRALKDAGFAPSELDKVILVGGSTRIPAVQEAIKRETGKEPYKGVNPDEVVALGAAVQGGVLTGDVEGVLLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMSADNKTLGRFQLTDLPPAPRGIPQIEVTFDIDANGIVNVRAKDLGTSKEQAITIQSSSGLSDEEVERMVQEAEANADADQKRKEEVELRNEADQLVFQTDKVVKDLEGKVDAAEVAKATEAKEALQAAIEKNELEEIRAKKDALQEIVQQLTVKLYEQAQAAAGQAEGAEGAQDAGAKKDNVVDAEFEEVKEDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y825_CHLMU
Sequence: MNISGSIKQKLLQFLKKQKSPELLATYLFYLEQSLHLSPVVFVRDKVIFKSAEDAIALLEADKKIWRETEIQISSGKPEVNEQTKRIYICPFTGKVFADNVYANPLDAVYDWLSSCPQNKERQAGVAVKRFLVSDDPEVIRAYIVPPKEPLIKTVYASAITGKLFHSLPTLLEDFKTSYLRPMTLEEVQNQNKFQLESSFLTLLQDALEEEKIAEFVESLADDTAFHEYISQWVDTEE
What are the official names of this protein?
Uncharacterized protein TC_0825.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0658/CT_538/TC_0825 family.
Protein: DDDI_BURC1
Sequence: MYADDFDGEIEIDEVDSLVEFLSRRPAFDANNFVLTFEESGFPQLNIFAKNDIAVVYYMDIGENFVSKGNSASGGTEKFYENKLGGEVDLSKDCVVSKEQMIEAAKQFFATKQRPEQLTWSEL
What is the function of this protein?
Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system.  CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion.  Bacteria that have this module inhibit or kill bacteria without it, giving them a growth advantage.  Specifically inhibits the toxic activity of cognate toxin DddA (C-terminal 163 residue fragment) upon expression in E. coli.
What are the official names of this protein?
Double-stranded DNA deaminase immunity protein, DddI.
Protein: RS20_LACPL
Sequence: MPIIKSAIERVKTNNKANVRNTAQMSAMRTAVKKFEAAKTAGADNVDDLYLAATSAVDKAASKGLIKRNKAARDKSRMAARYAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PALY_CITLI
Sequence: MELSHETCNGIKNDRNGGTSSLGLCTGTDPLNWTVAADSLKGSHLDEVKRMIDEYRRPVVKLGGESLTIGQVTAIAAHDSGVKVELAEAARAGVKASSDWVMDSMMKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNSGIFGNGTESSHTLPHSATRAAMLVRVNTLLQGYSGIRFEILETITKFLNHNITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAVGSNGQVLNPTEAFNLAGVTSGFFELQPKEGLALVNGTAVGSGLAATVLFEANILAIMSEVLSAIFAEVMNGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYVKAAQKLHETDPLQKPKQDRYALRTSPQWLGPQIEVIRAATKMIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNTRLAIASIGKLMFAQFSELVNDFYNNGLPSNLTGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLNSSRKTAEAVDILKLMSSTFLVALCQAIDLRHLEENLKNTVKNTVSQVAKRVLTMGVNGELHPSRFCEKDLIKVVDREYVFAYIDDPCSASSPLMQKLRQVLVDHALDNGDREKNSTTSIFQKIGAFEDELKTLLPKEVEIARTELESGNAAIPNRIKECRSYPLYKIVREDIGTSLLTGEKVRSPGEEFDKVFTAMCEGKLIDPMLECLKEWNGAPLPICQN
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_COXB2
Sequence: MSVEKQTAMRRTFAIISHPDAGKTTLTEKLLLFGGAIQLAGTIKSRKAARHATSDWMELEKQRGISVTTSVMQFPYKDYLINLLDTPGHADFTEDTYRTLTAVDSALMVIDAAKGVEPRTIKLMEVCRLRHTPIITFINKMDRDTRPSIELLDEIESILRIHCAPVTWPIGMGKYFKGIYHLIEDAIYLYQPGKHERVGESERIEGINNPELDKKLGDLASELRNEIELVKGASHPFEREGYLKGELTPIFFGSAINNFGVGELLDAFVKEAPPPQGRETNSRLVKPEEEKFSGFVFKIQANMDPGHRDRIAFLRIASGQYQKGMKAYHVRLKKEIQINNALTFMASKRENAEEAWPGDIIGLHNHGTIQIGDTFTQGERFKFTGIPNFASELFRLVRLKDPLKQKALLKGLTQLSEEGATQLFRPLDSNELILGAVGLLQFDVVAYRLENEYNVKCVYESVNVVTARWVICDDKAVLERFNQEQSRNLAYDGGGHLTYLAPSRVNLEITMEKWPEIQFSETREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.