PharMolix/UniProtQA huggingface dataset:
Protein: HMCES_CHICK
Sequence: MCGRTACSLGAARLRRACAYRDRQGRRQQPEWLREGRYRPSYNKGPQSSGPVLLSRKHVQQDADSSERVLMDMRWGLVPSWFKEDDPSKMQFKTSNCRSDTMLSKSSYKGPLLKGKRCVVLADGFYEWQQRGGGKQPYFIYFPQNKKHPAEEEEDSDEEWRGWRLLTMAGIFDCWEPPKGGEPLYTYTIITVDASEDVSFIHHRMPAILDGDEAIEKWLDFAEVPTREAMKLIRPAENIAFHPVSTFVNSVRNDTPECLVPIELGVPKEVKATASSKAMLGWLKSSQEGSPQKKEDTLPRWKSQFIHSPSPKKSSAGILRQWLGQEGGPPAKKQKA
What is the function of this protein?
Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites.  Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue.  The HMCES DNA-protein cross-link is then degraded by the proteasome.  Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks.  Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction (By similarity).  Acts as a protease: mediates autocatalytic processing of its N-terminal methionine in order to expose the catalytic cysteine (By similarity).
What are the official names of this protein?
Abasic site processing protein HMCES, Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, ES cell-specific 5hmC-binding protein, Peptidase HMCES, SRAP domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SOS response-associated peptidase family.
What are the subcellular locations of this protein?
Chromosome. Note=Recruited to chromatin following DNA damage. Localizes to replication forks.
Protein: NR6A1_HUMAN
Sequence: MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
What is the function of this protein?
Orphan nuclear receptor.  Binds to a response element containing the sequence 5'-TCAAGGTCA-3'.  May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 6 group A member 1, Germ cell nuclear factor, GCNF, hGCNF, Retinoid receptor-related testis-specific receptor, RTR, hRTR.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NAHQ_PSEPU
Sequence: ADIDVSRNWFVSIDIRKLYLKTDASGYLGPQEAKAKVTLDPLITSIAIGRQF
What is the function of this protein?
May be involved in the conversion of 2-hydroxy-4-(2'-oxo-3,5-cyclohexadienyl)-buta-2,4-dienoate to cis-O-hydroxybenzylidenepyruvate.  DoxH and DoxJ encode different enzymes that may have interchangeable functions.
What are the official names of this protein?
Dibenzothiophene metabolism operon protein NahQ/DoxH.
Protein: SPT16_ASHGO
Sequence: MSEVIIDFSTFENRLLALRDRFPSFDGSPSSLVFILGSADEENPYQKTTILHNWLLGYEFPTTLIAVFKEGCVVITSAAKTRYLEEGVAQMNKKLENTFKIELWQSSKEPGHNLKLFEDLVERVREAGSAVGLATKDSYQGKFITEWKGVWDTAVEKHGLNGVDVSLGLSSLWAVKDEKEQAYLQVSSRGSDKFMNLLSDELVRAVDEEIKITDAKLSDNVENEIDKSRFLKKLSPELTPLCPKGEKFDVNYLDWAYSPIIQSGPKYDLRVSARSSETQLDGNGCILASCGIRYKNYCSNISRTFLIDPSDEMTDNYDFLLLLQEEIINNLLRVGATPKQIYDGAVNYINSKKPELSAGFTKNVGSLMGLEFRDSQFVLNNKNDYRKVENGDCFNISLGFNNLKDSKTGASYALQLADTVQLTSGGPKVLTNYTKSRSQISFYFNNEDDGTTKVKSEESKTASIPTKPDPKSKILRSKLRGESRAEDDEKEQIRKENQRKLHEKLQREGLLRFTDTDAADKDQKPVVHFKKYESYVRETQIPNTVRDLRIHVDWKNQTFILPIYGRPVPFHINSYKNGSKNEEGEYTYIRLNFHSPGTGGVSKKTEELPYEDSPDHQFVRSLTLRSKDGDRMADIFKQITELKKESTKREQERKVLADVVEQAKLVENRTGRTKRLDQIFVRPSPDTKRVPGTVFIHENGIRYQSPLRTDSRIDILFSNVKNLFFQPCKGELIVIIHIHLKNPILMGKKKIQDVQFYREASDMAVDETGNGRRNQMKFRRYGDEDELEQEQEERRKRAALDKEFRYFAEAIAEASNGLVEVDHPFRDLGFQGVPSRSAVFCMPTRDCLIQLVEPPFLVVNLSEVEICILERVQFGLKNFDMVFVYKDFTKPVTHINTIPIEQLEFIKSWLTDVDIPYTVSTINLNWATIMKSLQDDPHQFFLDGGWSFLATGSDDEMSGTSEEEVSEYEVSDEDPSDEEVDSEDDYSEGDNEEFSDEGSEDFSGEESEEGEDWDELEKKAAKADRGNRFAD
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit SPT16, Facilitates chromatin transcription complex subunit SPT16.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. SPT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NMO_STAAS
Sequence: MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIGAGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLEEPVVKITEEQQFKCHIDTIIKKQVPVCCFTFGIPSESIIKRLKEANIKLIGTATSVDEAIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGGIMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVVTKAFSGKLARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELTHMWSGQSPRLATTHPANTIVSNIINQINQIMQYK
What is the function of this protein?
Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates.  Acts on propionate 3-nitronate (P3N), the presumed physiological substrate.  Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.
What are the official names of this protein?
Probable nitronate monooxygenase, NMO, Propionate 3-nitronate monooxygenase, P3N monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family. NMO class I subfamily.
Protein: RMD3_XENLA
Sequence: MSKLILSYRIGLGLVVGAAAGAVIYIVFRRNRKKTRKWTSKQNGYYSQKGDELDTSNNLQAIPGEADILTGSRGEQLDLLNRLDYVLSSIVELHQEVETLRSSLHGLAEDIVGEVRTHLEENQRTLRRRRFLPHRERTDSTGSSSIYFTATSGAAHTDAESEGGYSTAYAESDFERESSRASEAEEEDEVSCETIRTMRRDSVDLVTDDDDDEATTIATDPVDEELTLLLQKSDELHSGSTEQQREGFQLLLNNKLLYGDHQEFLWRLARSYSDMCTIAEDAQEKKSFASEGKEEAEAALQKGDQNAECHKWFAILCGQLSEHEGIQKRIQTGYLFKEHIEKAISLKPGDARCYYLLGRWCYEVSNLGWLERKTASALYENPPTATVHEALQNFLKAEDLTPGFSKAARVLIAKCYKDLGNNATAAHWLKLAADLPNVTQEDRESTTTIEEMLPATAEEELLV
What is the function of this protein?
Involved in cellular calcium homeostasis regulation.
What are the official names of this protein?
Regulator of microtubule dynamics protein 3, RMD-3, Protein FAM82A2, Protein FAM82C.
What is the protein family that this protein belongs to?
Belongs to the RMDN family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.
Protein: DUT_SHIBS
Sequence: MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: CCD80_CHICK
Sequence: MNWMPALSLALLWTAWLVCGSEKTGRLAERGSHGVRKVPQSHRAPSSLLRRSGASLKNLSPSPQHPVTKRDSSVPPKAPANLLKEESRSQPRSVGTRTRRLQRLTAAAKYSKSEMIKDEGISTASQSRAVRFPSGSSSPNVLASFAGKNRVWVISAPHASEGYYRLMMSLLKNDVYCELAERHIQQIVLFHEEGEEGGKVRRITNEGKILEQPLDPALIPKLMSFLKLEKGKFGMVLLKKTLQVEERYPYPVRLEAMYEVIDQNPIRKIEKMRQKGFIQTCKAAGVEGQVVEDDNNGGSTQSIPGGGHVQVSAGGRKEEPRRSSNQPTRTKTVRKPMTTTVATPLPTVRTTTLPTTTTATRATTRTVTTASRPTTTTTPLPTTQRTWTTKSHTTTEYHRLPASPEVTTPRVMASEDFYSPVWKANRRDRQRGHPEKHLAATRKPSKGGRYESFTEVPTAPSVHYTKASMSRFKDNRTDRKDYNHRDLNVTPGQHKPTKTKPPKKKTQEKILSNEYEDKYDPSKPASPHLEEEIAVGSIPPKKGKESKKHERMDKPEKKKKKDRPDKLHKSEKQSKKDKAEKKSKQDKDRSKKNKKGSRTENEDFPKPNKKPFLQPPRKSVANLLDYFEGKRRLILITTPKADNTMYVQQRDEYLESFCKMATRKISVITIFGTMNNSSMKIDHFQLDNEKPMKVIEDEDLVDQQLISELRKEYGMTYNDFFMVLTDTDMKVKQYYEVPIAMKSVFDLIDTFQSRIKDMERQKKEGIVCKEDKKQSLESFLSRFRWRRRLVVISAPSDEDWAYSQQLAALSGQACNFGLRHITILKLLGVGEDIGGVLELYPINGSATVDREDIPANLVKDIRNYFQISPEYFSMLLVGKDGNVKSWYPSPMWSMAIVYDLIDSMQLRRQEMTIQQSLGMQCPEDEYGGYGYHSYHQGYQEGYQDDYRHHGSYHHGYPY
What is the function of this protein?
Promotes cell adhesion and matrix assembly (By similarity).  May play a role in eye formation.
What are the official names of this protein?
Coiled-coil domain-containing protein 80, Equarin.
What is the protein family that this protein belongs to?
Belongs to the CCDC80 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RF1_SYNP6
Sequence: MAEPYLIEKLQSVEQTFQDLTRRLADPEIATDPREFQRVARMRSSMEELVTTYEEWKQRDAELKGAREILRESSGDPELREMAALEVNELEALLVSLEERLKILLLPRDPNDDKNIMLEIRAGTGGDEASLWAGDLLRMYSRYAESQGWRVKLLSESTGELGGYKEAILEIQGESVYSKLKFEAGVHRVQRVPATEAGGRVHTSTATVAIMPEVDEVEVSIDPKDIELTTARSGGAGGQNVNKVETAVDLFHKPTGIRIFCTEERSQLQNRERAMQILRAKLYEMKLQEQQEAVSSMRRSQVGTGSRSEKIRTYNYKDNRATDHRLGLNFSLNPVLEGEIEEVIQACISKDQTEQLAQMAQDQEAAKV
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDM4B_HUMAN
Sequence: MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSPELSSWSASRASLKAKLLRRSHRKRSQPKKPKPEDPKFPGEGTAGAALLEEAGGSVKEEAGPEVDPEEEEEEPQPLPHGREAEGAEEDGRGKLRPTKAKSERKKKSFGLLPPQLPPPPAHFPSEEALWLPSPLEPPVLGPGPAAMEESPLPAPLNVVPPEVPSEELEAKPRPIIPMLYVVPRPGKAAFNQEHVSCQQAFEHFAQKGPTWKEPVSPMELTGPEDGAASSGAGRMETKARAGEGQAPSTFSKLKMEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEASPFSGEEDVSDPDALRPLLSLQWKNRAASFQAERKFNAAAARTEPYCAICTLFYPYCQALQTEKEAPIASLGKGCPATLPSKSRQKTRPLIPEMCFTSGGENTEPLPANSYIGDDGTSPLIACGKCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTAECCLCNLRGGALQMTTDRRWIHVICAIAVPEARFLNVIERHPVDISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHKSGGHAVQLLRAVSLGQVVITKNRNGLYYRCRVIGAASQTCYEVNFDDGSYSDNLYPESITSRDCVQLGPPSEGELVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGAPQEPAFSGEEAKAAKRPRVGTPLATEDSGRSQDYVAFVESLLQVQGRPGAPF
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code.  Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'.  Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D.  Demethylation of Lys residue generates formaldehyde and succinate (PubMed:16603238, PubMed:28262558).  Plays a critical role in the development of the central nervous system (CNS).
What are the official names of this protein?
Lysine-specific demethylase 4B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, [histone H3]-trimethyl-L-lysine(9) demethylase 4B.
What is the protein family that this protein belongs to?
Belongs to the JHDM3 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EST3B_MOUSE
Sequence: MTNMRTMIPAGSSVLVWVTCLLLAFVTTVTGPKVIQPEVDTPLGRVRGRQVGVKDTDRMVNVFLGIPFAQAPVGPLRFSAPLPPQPWEGVRDASINPPMCLQDVEKMINSRFGLNEKIKIFPISEDCLTLNIYSPTEITAGDKRPVMVWIHGGSLLVGSSTSQDGSALAAYGDVVVVTVQYRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGNIAPFGGDPNCVTIFGNSAGGMIVSSLFLSPISAGLFHRAISQSGIVTTIMMEDMKPWPEAQNFANSVACGSASPAELVQCLLQKEGKDLIKQKNVNISYIVNDSFFPQRPEKLLADQQFPTVPYLLGVTNHEFGWLLLKSLNILDKLEHLSREDLLEISRPFLAIMEVPPEIMPTVIDEYLDNGSDQSATRYAFQELLGDISFIIPTLNFSKYLRDAGCPVFLYEFQHTPSSFAKFKPAWVKADHASENSFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNPNGKGLPPWPQLNQLEQYLEIGLESRTGVKLKKGRLQFWTETLPRKIQEWHREQRSRKVPEEL
What is the function of this protein?
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs.
What are the official names of this protein?
Carboxylesterase 3B, Liver carboxylesterase 31-like.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: ACES_TETCF
Sequence: MNLLVTSSLGVLLHLVVLCQADDHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNATACDGELSSSGTSSSKGIIFYVLFSILYLIF
What is the function of this protein?
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.  May be involved in cell-cell interactions.
What are the official names of this protein?
Acetylcholinesterase, AChE.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
[Isoform H]: Cell membrane; Lipid-anchor, GPI- anchor. Synapse. SUBCELLULAR LOCATION: [Isoform T]: Cell membrane; Peripheral membrane protein. Synapse. Note=Attached to the membrane through disulfide linkage with the collagenic subunit, itself bound to the membrane.
Protein: RL4_CHLL3
Sequence: MELKVLNTAGAETGEVVTLRDDIFGAEVSEHAIWLDVKSILANKRQGTHKSKTRAEVRGGGRKPYRQKGTGNARQGSTRSPLMIGGGTIFGPTPHGYDQKVNRKVKQLARRSAFSAKAQEGRILIVEDFALAEIKTKPVADMLRNLGLDAKKILMLTPDYNMVIARSGRNIEALNIMTAEKASTYDILNSHTVLFQKTALKKLEETLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NU6M_CALMA
Sequence: MTYLVLLLGLCFVLGGLAVASNPSPYYGVVGLVLASVAGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWRVVGYGASFILVVIAGMIVGGLIECWKVGVVTVDSGGMFSVRLDFSGVAMFYSYGVGMFLVAGWGLLLTLFVVLELVRGLSRGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RL36_TREDE
Sequence: MKVRTSVKPICDKCKVIKRNGIVRIICTNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RECF_ECO27
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
Plays a role in recovery after DNA ADP-ribosylation.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPAS1_HUMAN
Sequence: MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRKEKSRNAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPPWGLRAAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPGPPTPPSVSSSSSSSSSLADTPEIEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVIHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPGTIRYGPAELGLVYPHLQRLGPGPALPEAFYPPLGLPYPGPAGTRLPRKGD
What is the function of this protein?
May control regulatory pathways relevant to schizophrenia and to psychotic illness.  May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level (By similarity).  Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH (By similarity).
What are the official names of this protein?
Neuronal PAS domain-containing protein 1, Neuronal PAS1, Basic-helix-loop-helix-PAS protein MOP5, Class E basic helix-loop-helix protein 11, bHLHe11, Member of PAS protein 5, PAS domain-containing protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPB_ECO5E
Sequence: MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: HSLV_CAMFF
Sequence: MFHATTILAYKGNKGSIIGGDGQVSFGNTVLKGNAVKIRKLLGGKILAGFAGSTADAFNLFDMFERILESTKGDLLKAVIEFSKEWRKDKVLRKLEAMMLVLDREHIFLLSGTGDVVEPEDGKIAAIGSGGNYALAAARALDKFADINEEELVKESLKIAGEICIYTNTNIKTYALWDEK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBIP1_HUMAN
Sequence: MASCPDSDNSWVLAGSESLPVETLGPASRMDPESERALQAPHSPSKTDGKELAGTMDGEGTLFQTESPQSGSILTEETEVKGTLEGDVCGVEPPGPGDTVVQGDLQETTVVTGLGPDTQDLEGQSPPQSLPSTPKAAWIREEGRCSSSDDDTDVDMEGLRRRRGREAGPPQPMVPLAVENQAGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECARQEGLTFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFFGEDGIFRHDRLRFRDFVDALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHSQSPRAAGPREGHSHSHHHHHRG
What is the function of this protein?
Regulator of pre-B-cell leukemia transcription factors (BPXs) function.  Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1.  Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
What are the official names of this protein?
Pre-B-cell leukemia transcription factor-interacting protein 1, Hematopoietic PBX-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol (PubMed:12360403). Mainly localized in the cytoplasm, associated with microtubules (PubMed:10825160, PubMed:12360403). Detected in small amounts in the nucleus (PubMed:10825160).
Protein: TGT_NEIG1
Sequence: MLKFTLHKKDGLARRGTLELNHGKIETPVFMPVGTYGSVKAMNPQNLHDIKAQIILGNTYHLWLRPGLEVVEQFGGLHGFIGWDKPILTDSGGFQVFSLSDMRKLTEEGCTFKSPINGDKLFLSPEISMKIQTVLNSDIAMQLDECTPGETTREQARKSLQMSLRWAERSKKAFEDLKNPNALFGIVQGAMYEDLREESLRGLEEFDFPGLAVGGLSVGEPKPEMYRMLHAVGPMLPERKPHYLMGVGTPEDLVYGVAHGIDMFDCVMPTRNARNGWLFTRFGDLKIKNAKHKPDKRPIDESCTCYACQNFSRAYLHHLHRAGEILGAQLNTIHNLHFYQVIMAEMRDAVEQGKFADWQAQFHENRARGVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PAH_STRCL
Sequence: MERIDSHVSPRYAQIPTFMRLPHDPQPRGYDVVVIGAPYDGGTSYRPGARFGPQAIRSESGLIHGVGIDRGPGTFDLINCVDAGDINLTPFDMNIAIDTAQSHLSGLLKANAAFLMIGGDHSLTVAALRAVAEQHGPLAVVHLDAHSDTNPAFYGGRYHHGTPFRHGIDEKLIDPAAMVQIGIRGHNPKPDSLDYARGHGVRVVTADEFGELGVGGTADLIREKVGQRPVYVSVDIDVVDPAFAPGTGTPAPGGLLSREVLALLRCVGDLKPVGFDVMEVSPLYDHGGITSILATEIGAELLYQYARAHRTQL
What are the official names of this protein?
Proclavaminate amidinohydrolase, Proclavaminic acid amidino hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: RL33_CERS5
Sequence: MAKPTTIKIRLNSTAGTGHFYVTKKNARTMTDKMVVRKYDPVKREHVEYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.