PharMolix/UniProtQA huggingface dataset:
Protein: QUEC_RICCN
Sequence: MKKKAVILLSGGPDSTTVLEIVSKTDYEIYALSFNYHRRNSLEVQKIQGLIKDYNVKQHRVINIDLQSFIGSALTDDNIDVPKFQNTDQLPSDIPVTYVPARNTIFLSYALGVAEVIGARDIFIGVHTNDYTNYPDCRPEYIKSFEAMANLATRVGVNGEKITIHAPLINMTKEQIIKKGLELGVDYSKTISCYDPTEDGLSCGQCLSCIARLDAFKKNNVQDPIKYV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ARGT_ECOLI
Sequence: MKKSILALSLLVGLSTAASSYAALPETVRIGTDTTYAPFSSKDAKGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQEIAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVVAYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGSSVKDKKYFGDGTGVGLRKDDAELTAAFNKALGELRQDGTYDKMAKKYFDFNVYGD
What is the function of this protein?
Part of an ABC transporter involved in lysine, arginine and ornithine transport.  Stimulates ATPase activity of HisP (By similarity).
What are the official names of this protein?
Lysine/arginine/ornithine-binding periplasmic protein, LAO-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUOD1_CYTH3
Sequence: MESSEPLVLDVGNLKRGEIIINMGPQHPSTHGVLRLEILTDGEIVKDVIPHMGYLHRCYEKHAEKLPYNQVIPFVDRMDYLAAMNSEHAYAMGVERMLGIENDIPKRVEYIRVLVAELNRISSHFVAIGTYGLDIGAFTPFLWVMRDREHINRLLEWVSGARMLYNYIWVGGLFYDLPVGFEERCKDFISYLKPKLAELQKVIIDNKIFIERTANIGVLPLDLAINYGITGPMLRASGLKFDLRKVDAYSVYPEIDFDIPVGTGAVGTTGDCWDRTHVRVAECFESVKIIEQCLEKLLGEHKRTREFDPQAIVPKKIRPKVMDFYVRAENPKGELGFFFRTTGNTDIPFRCKVRAPSFVNLSVLQAISKNVMIADLVAILGSFDIVMGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 1, NADH dehydrogenase I subunit D 1, NDH-1 subunit D 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NQO11_THET8
Sequence: MSYLLTSALLFALGVYGVLTRRTAILVFLSIELMLNAANLSLVGFARAYGLDGQVAALMVIAVAAAEVAVGLGLIVAIFRHRESTAVDDLSELRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient required for the synthesis of ATP.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 11, NADH dehydrogenase I chain 11, NDH-1 subunit 11.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FAR6_PANRE
Sequence: NGAPQPFVRF
What is the function of this protein?
Myoactive.
What are the official names of this protein?
FMRFamide-like neuropeptide PF6, NGAPQPFVRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPF_CLOBJ
Sequence: MRIGLGYDVHKLVEDRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: DCD_SALTI
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: QUEA_GLOVI
Sequence: MNAPIDERDFLTDSYDYALPERCIAQQPAEPRDHSRLLVVDGEAHTHRYFYDLPGLLRPGDLLVLNDTRVIPARLFGSKASGGRVEVLLLEPRAPREWLCLVKPARRLAVGARIDFDGVLAARVTELDAETGGRWLRFEGEEDFEAALERVGHTPLPPYLKTGRTRDERYQTLWASRPGAVAAPTAGLHFSGELLARLAERGIERATVTLHVGLGTFRPVQSVSVHTHRMHREWYEIPEATAIAIERTRSRGGRVLAVGTTSARALESAAQPNGLPATGPGRSELFVYPGYRWRVVEGLITNFHLPRSSLLMLVSSLVGRERLLALYREAVDKGYRFYSFGDAMLILPGAGA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8495_HAEIG
Sequence: MLAIISPAKTLDFESAVKNFPVSQPHFTDYSEQLIEVCRKLSPQDLSSLMSISDKLAGLNAARFAEWTKIHNENNSRPALFAFKGDVYTGLDADSLSEDDVIFAQSHLRMLSGLYGLLKPLDLMQPYRLEMGTKLANPKGKDLYAFWGNVITQAVQQAIDAQGDNVLVNLASDEYYKSVKENQLNAKIIKPVFLDNKNGKYKVISFYAKKARGLMCRYLIQHRLTNIEQLKEFDLAGYWFDSASSTETEFVFKRDINE
What are the official names of this protein?
UPF0246 protein CGSHiGG_08495.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SSRP_EHRRG
Sequence: MDIIIENRKVRFNYFIIQEFDAGIVLIGSEVKSLRQRKVSIAESYVTERNMELWLCNLHISEYTQANTKNHNPTRPRKLLLKKKQIYKISGNMKNDGFTVVPLFLYFNDKGIAKAKIVIVKGKKLHDKRETIKARDWNREKNRILRGG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: DSBA_PSESM
Sequence: MRNLIISAALVAASLFGMSAQAAEPIESGKQYVELTSAVPVAVPGKIEVIELFWYGCPHCYAFEPTINPWVEKLPSDVNFVRIPAMFGGPWDAHGQLFITLDTMGVEHKVHAAVFEAIQKGGKRLTDKNDMADFVATQGVNKDDFLKTFDSFAVKGKIAQYKELAKKYEVTGVPTMIVNGKYRFDLGSAGGPEKTLQVADQLIDKERAAAKAAK
What is the function of this protein?
Involved in disulfide-bond formation.  Acts by transferring its disulfide bond to other proteins (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: NU1M_PERGU
Sequence: MFIINLLLYIVPILLAVAFLTLIERKVLGYMQFRKGPNIVGPYGLLQPFADAVKLFTKEPLRPLTSSISMFIIAPILALTLALTIWVPLPMPYSLIDLNMGLLFILALSGLSVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSIMLINGSFTLKTLITTQENMWLIVTTWPLAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFAMFFLAEYANIIVMNAMTTILFLGTSINQNFTHLNTLSFMMKTLTLTIVFLWIRASYPRFRYDQLMHLLWKNFLPITLACCLWFISMPIALSCIPPQI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PQQB_METFL
Sequence: MHIHVLGSAAGGGFPQWNCNCPNCDGLRKGTIKAKKRTQSSICVSADGINWVLFNTSPDILQQIQEFAPLQPGRAIRDTGVVGIVLIDAQIDHTTGLLMLREGQVKREIYCTDMVYQDLTTGNPLLNILDHYCGVNRHDIPIDGKHSFSVEHAPGLRFTAVALKSAAPPYSPHRHDPHPGDTIGVLIEDLNNGKKAFYAPGLGEIEPHLPALMEQADCIMVDGTFWTDTEMLDMGLMSKKARDIGHNPQSGPGGMMEVLDGYPGARRVLIHINNTNPILREDSAERVELTRRGIEVAYDGMDIIL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: RL28_VIBCH
Sequence: MSRVCQVTGKRPAVGNNRSHAKNATKRRFLPNLQTHRFWVESEKRFVKLRLTAKGMRIIDKKGIDAVLVEIRARGENV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MATK_ROSCA
Sequence: MEEFQGYLELYRSQQHDFLYPLIFREYIYALAHDRGLNRSVLLDNVGYDKKSSLLIIKRLISRMYQQNHFLISVNDSNQNKFFGYNKNLYSQIISEGFAVIVEIPFSLRLVSSLKETETVKSYNLRSIHSIFPFFEDKFPHLNYASDVLIPYPIHLEILVQTLRYCVKDPPSLHLLRLFLHEYYNWNTLITPKKSIFAKSNQRLFLLLYNSYVCEYESILLFLRNQSNHLRLTSSGILFERIRFYEKIKYPVEEVFANDFPATLWFFKDPFIQYVRYQGKSILASKDTPLLMNKWKYYLVHFWQCHFYVWSQPGRIHINQLSKHSFDFLGYLSSIRPNISVVRSQLLENSFLMDNAMKKLDTLFPIIPMIGSLAKVKFCNTSGHPISKSSWADSSDSDIIDRFVRIGGNLSHYYSGSSKKKSLYRIKYILRLSCVKTLARKHKSTVRTFLKRLGPKLLDEFFTEEEQIFSLLFPRTSSTLKRFYRGRIWYLDILCINDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABZ_LIGS1
Sequence: MLDITEIKKIIPHRYPMLLIDRVEELIPGEKAVAKRNVTINEELFNGHFPGNPVMPGVLIVEALAQTGAVALLSLPEFKGKTAYFGGIKSAKFRKVVRPGDSLRLEVTLEKIRNNVGLGKAIATVDGKKACTAELTFMIG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_SHEAM
Sequence: MRKIIHIDMDCYFAAVEMRDFPQYRGKPLAVGGSSDRRGVISTCNYEARAFGVRSAMASAYALKLCPNLILVPGRMEVYKAVSQQIREIFSRYTSLIEPLSLDEAYLDVSDCSLYQGSATRIAEAIRSDIFKETGLTASAGVSPIKFVAKVASDLNKPNGQYVVSPDTLMHFVRALSLGKIPGVGKVTEEKLNALGLKTCADVQQVPQTLLTEHFGKFGAVLYERAHGRDERAIVSHRERKSVGVETTLPKDLHTREACLDVLSSLIPELNRRLGRSASGRRIHKLVVKLKFDDFRQTTIESRAEEPSVRLFESLLSQAFVRAEGRGIRLVGIAAGLVCRSEAEQEGSAQLALSL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BRUA4
Sequence: MGQKINPIGLRLGINRTWDSRWYANTGEYGKLLHEDVKIREFLTEELKQAAISKIVIERPHKKCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTNADTSLNIVEVRKPEIDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRLGAEGIRINCSGRLGGAEIARMEWYREGRVPLHTLRADIDYGTAEAKTAYGICGVKVWVFKGEILEHDPMASERRAVEGDNQGSSSNRRRENA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: AROA_BARQU
Sequence: MQKTTPITAYKSTCLSGKIKIPGDKSISHRSLILGGLANGETHIHGLLESDDVLNTAAAMQAMGACIIKKADRWIIRGTGNGCLLAAEKPLNFGNAGTGARLVMGMVGPYHMKTTFIGDASLSKRPMGRILNPLRLMGVEIEATHGDRLPLTLYGPKMANPIRYRIPIASAQVKSAILLAGLNTAGTTTVIEPILTRDHTEKMLKAFGAELEIKTDAEGTRFIHLNGQPHLTGQTIHIPGDPSSAAFPIIAALLVENSDITIENVLINKSRMGLIETLWEMDAKIELLNQHKTGGENVADLRVKSSMLKGVTVPKERAPSMIDEYPALAVAAAFAEGKTVMLGIDELRVKESDRLSALAQGLKINHVDCEEGKDFLIVHGKSSAKGLGGGHVTTHLDHRIAMSFLIFGLVSEKPVTIDDKRMIATSFPEFIPFIQQLGGKIS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAO_ORYSJ
Sequence: MVEIPAIDLRLAGGGGGAEETARLRDACARLGCFRVSGHGVPPGLQAEMKAAVRALFDLPDDAKRRNADIIPGSGYVPPGTANPLYEAFGLCDAAAPADVDAFCARLDAPPHVRETVKAYAERMHSLIVDVAGKVAASLGLHGASFQDWPCQFRMNRYNYTQDSVGSPGVQVHTDSGFLTVLQEDECVGGLEVLDPAAGEFVPVDPLPGSFVVNVGDVGQAWSNGRLHNVKHRVQCVAAVPRVSIAMFLLAPKDDTVSAPGELVDGEHPRRYREFKYDDYRRLRLSTGERAGEALARLAA
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase essential for auxin catabolism and maintenance of auxin homeostasis in reproductive organs.  Catalyzes the irreversible oxidation of indole-3-acetic acid (IAA) to the biologically inactive 2-oxoindole-3-acetic acid (OxIAA).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase DAO, Protein DIOXYGENASE FOR AUXIN OXIDATION.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: SMI45_HUMAN
Sequence: MSMAACPEAPEPSFLREVPSSPASTQWHRPCNFRQVEANPRKEPKNLVWRDVSLGQTSRTPRGSGLELVRVCGGGMQRDKTVVEERVGEERERERERVWGERASMGR
What are the official names of this protein?
Protein SMIM45, Small integral membrane protein 45.
Protein: PR19B_ARATH
Sequence: MNCAISGEVPVEPVVSTKSGLLFERRLIERHISDYGKCPVTGEPLTIDDIVPIKTGEIIKPKTLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKKERDEARQLLAEVERHIPAAPEAVTANAALSNGKRAAVDEELGPDAKKLCPGISAEIITELTDCNAALSQKRKKRQIPQTLASIDTLERFTQLSSHPLHKTNKPGICSMDILHSKDVIATGGVDATAVLFDRPSGQILSTLTGHSKKVTSVKFVGDSDLVLTASADKTVRIWRNPGDGNYACGYTLNDHSAEVRAVTVHPTNKYFVSASLDGTWCFYDLSSGSCLAQVSDDSKNVDYTAAAFHPDGLILGTGTSQSVVKIWDVKSQANVAKFDGHTGEVTAISFSENGYFLATAAEDGVRLWDLRKLRNFKSFLSADANSVEFDPSGSYLGIAASDIKVYQTASVKAEWNLIKTLPDLSGTGKATCVKFGSDAQYVAVGSMDRNLRIFGLPGDEKANVDDDSAQDS
What is the function of this protein?
Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair (By similarity).  Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity.
What are the official names of this protein?
Pre-mRNA-processing factor 19 homolog 2, MOS4-associated complex protein 3B, MAC protein 3B, Plant U-box protein 60, RING-type E3 ubiquitin transferase PRP19 2, U-box domain-containing protein 60.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRP19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLC4F_HUMAN
Sequence: MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN
What is the function of this protein?
Receptor with an affinity for galactose and fucose.  Could be involved in endocytosis (By similarity).
What are the official names of this protein?
C-type lectin domain family 4 member F, C-type lectin superfamily member 13, C-type lectin 13.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: CDD_ACTPJ
Sequence: MPTLFALKERIAQVVQEKNDPIVTAVATTLAEQQYNACFSAEQVKLWKRQFKCSSVELALACLPIAACYALVPISNFYVGAVAIGESGRFYFGANQEFNAQAIQQTVHAEQSAISHAWLAGETAITDMVVNYTPCGHCRQFMNELNSAKTLKIHLPHSQNNLLRQYLPDSFGPKDLNIEKVLFDQQTHSLPLRGDLLTQAAIQTAAQSYAPYSKSLSGIALQVGEQIICGRYAENAAFNPSFLPLQSALNYRRLSGKSDERISRIVMAESKGTTSHRQMSEALAESFLGLNLEYIEV
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: ADNP2_HUMAN
Sequence: MFQIPVENLDNIRKVRKKVKGILVDIGLDSCKELLKDLKGFDPGEKYFHNTSWGDVSLWEPSGKKVRYRTKPYCCGLCKYSTKVLTSFKNHLHRYHEDEIDQELVIPCPNCVFASQPKVVGRHFRMFHAPVRKVQNYTVNILGETKSSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFHYLINSYFGLRTEEMGEQPKTNDTVSIEKIPPPDKYYCKKCNANASSQDALMYHILTSDIHRDLENKLRSVISEHIKRTGLLKQTHIAPKPAAHLAAPANGSAPSAPAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLPINQTVRPGVLPLTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTPAGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGVLPVGQPVRPGVLQLNQTVGTNILPVNQPVRPGASQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPPGGLATVAPPQMPIQLLPSGAAAPMAGSMPGMPSPPVLVNAAQSVFVQASSSAADTNQVLKQAKQWKTCPVCNELFPSNVYQVHMEVAHKHSESKSGEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSEEELIHHLLMHGLGCLFCPCTFHDIKGLSEHSRNRHLGKKKLPMDYSNRGFQLDVDANGNLLFPHLDFITILPKEKLGEREVYLAILAGIHSKSLVPVYVKVRPQAEGTPGSTGKRVSTCPFCFGPFVTTEAYELHLKERHHIMPTVHTVLKSPAFKCIHCCGVYTGNMTLAAIAVHLVRCRSAPKDSSSDLQAQPGFIHNSELLLVSGEVMHDSSFSVKRKLPDGHLGAEDQRHGEEQPPILNADAAPGPEKVTSVVPFKRQRNESRTEGPIVKDEALQILALDPKKYEGRSYEEKKQFLKDYFHKKPYPSKKEIELLSSLFWVWKIDVASFFGKRRYICMKAIKNHKPSVLLGFDMSELKNVKHRLNFEYEP
What is the function of this protein?
May be involved in transcriptional regulation.  May play a role in neuronal function; perhaps involved in protection of brain tissues from oxidative stress.  May be involved in erythroid differentiation (By similarity).
What are the official names of this protein?
Activity-dependent neuroprotector homeobox protein 2, ADNP homeobox protein 2, Zinc finger protein 508.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NLEB1_ECO57
Sequence: MLSSLNVLQSSFRGKTALSNSTLLQKVSFAGKEYPLEPIDEKTPILFQWFEARPERYEKGEVPILNTKEHPYLSNIINAAKIENERIIGVLVDGNFTYEQKKEFLSLENEYQNIKIIYRADVDFSMYDKKLSDIYLENIHKQESYPASERDNYLLGLLREELKNIPEGKDSLIESYAEKREHTWFDFFRNLAMLKAGSLFTETGKTGCHNISPCSGCIYLDADMIITDKLGVLYAPDGIAVHVDCNDEIKSLENGAIVVNRSNHPALLAGLDIMKSKVDAHPYYDGLGKGIKRHFNYSSLHDYNAFCDFIEFKHENIIPNTSMYTCSSW
What is the function of this protein?
Protein-arginine N-acetylglucosaminyltransferase effector that disrupts TNF signaling in infected cells, including NF-kappa-B signaling, apoptosis and necroptosis (PubMed:28522607).  Acts by catalyzing the transfer of a single N-acetylglucosamine (GlcNAc) to a conserved arginine residue in the death domain of host proteins such as FADD: arginine GlcNAcylation prevents homotypic/heterotypic death domain interactions and assembly of the oligomeric TNF-alpha receptor complex, thereby disrupting TNF signaling (PubMed:28522607).  Also acts on host proteins without a death domain: catalyzes arginine GlcNAcylation of host GAPDH protein, thereby preventing GAPDH interaction with TRAF2, leading to inhibit NF-kappa-B signaling (PubMed:28522607).  Catalyzes auto-GlcNAcylation, which is required for activity toward death domain-containing host target proteins (By similarity).
What are the official names of this protein?
Protein-arginine N-acetylglucosaminyltransferase NleB1, Arginine GlcNAcyltransferase NleB1, Non-LEE-encoded type III effector B1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase NleB family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (TTSS).
Protein: HIS1_RHIEC
Sequence: MTITIALPSKGRMKDDASAIFERAGMTITAVGNDRSYRGRVEGWDDVEVAFLSASEISRELGNGTVDFGVTGEDLMREGFAEVDKRVEFCARLGFGHADVVVAVPEIWLDVDTMADLGDVAADFRARHSRRLAIATKYWRLTQQFFSSQHGIQLYRIVESLGATEGAPAAGSADIIVDITSTGSTLRANHLKVLQDGVILHSQACLVRARKESHADEPVVQAIIDAVRAAL
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_FRAT1
Sequence: MSDKIRLLEGKVSSVAMDKTVVVRAERYVKHPLYGKFVKKTTKYYVHDENNECKEGDVIKFKETRPYSKTKKWCLVDIIHREK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: MSCL_VARPS
Sequence: MSILSEFKEFAVKGNVIDLAVGVIIGAAFGKIVDSIVADIIMPVVGLVFGKLDFSNLYVVLGTVPAGVANNLADLKKAGVPVLAYGNFITIAVNFVILAFIIFMMVKQINKLRKTHAEAPAAPVAPPEDIALLREIRDSLKRP
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.