PharMolix/UniProtQA huggingface dataset:
Protein: DTD_SHEB9
Sequence: MIALIQRVSRASVVVDNQTIGAIDKGLLVLLGVEQEDTREKMEKLATKVMSYRVFSDENGKMNLNLEQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQALALYEEFVAFCRAKGVTTETGQFGADMQVSLVNDGPVTFNLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_STRT2
Sequence: MERSMYAGRVRSEHIGTTITLKGWVSRRRNLGGLIFIDLRDREGLMQLVVNPENADAAVVETAESLRSEFVIEVTGTVEAREQANDNLPTGAVELKVKDLKVLNTAKTTPFEIKDGVEASDDTRMRYRYLDLRRPEMLENFKLRAKVTHTIRNYLDDLEFIDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLNEQEIQDITEGLIAKVMKETKGVEVTLPFPRMSYDDAMNNYGSDKPDTRFDMLLQDLTELVKDVDFKVFAEAPAVKAIVVKGNADKYSRKSIDKLTDFAKQFGAKGLAWVKMTDGVLAGPVAKFLTSIEEKLTDTLQIEENDLVLFVADTLEIANNTLGALRNQIAKELDMIDNTKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPTEDSAAELEGDLSKVRAVAYDIVLNGYELGGGSLRINQKDLQERMLKALGFSEESAYEQFGFLLEAMDYGFPPHGGLALGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLVADKQLEELALHVELENE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RACYE_PELLE
Sequence: SAPRGCWTKSYPPKPCK
What is the function of this protein?
Has antibacterial activity against Gram-positive bacteria B. megaterium Bm11, S. lentus and M. luteus, Gram-negative bacteria Y. pseudotuberculosis YP III and P. syringae pv tabaci, and antifungal activity against C. tropicalis, C. guiller-mondii and P. nicotianae spores.  Has hemolytic activity.  The mature peptide inserts into the hydrophobic core of the bacterial cell membrane and increases permeability without disrupting membrane integrity.  Probably binds to the outer membrane surface before aggregating to form transmembrane pores.
What are the official names of this protein?
Ranacyclin-E.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSN_ECO8A
Sequence: MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: EFG_PROM9
Sequence: MARDFPLERVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTSWQDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVNNQIKDRLKANALPIQLPIGAEGDLTGIIDLVANKAYLYKNDLGTDIQEAPIPSEMDDEAAEWRYKLMESVAENDEELIETFLETGELSEEQLKKGIREGVLKHGLVPVLCGSAFKNKGVQLVLDAVVDYLPAPVDVKPIQGVLPSGKEDVRPSDDNAPFSALAFKVMSDPYGKLTFVRMYSGVLSKGSYVMNSTKDAKERISRLVILKADEREEVDELRAGDLGAVLGLKNTTTGDTLCNTEDPIVLETLFIPEPVISVAVEPKTKGDMEKLSKALTALSEEDPTFRVSTDPETNQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRETIRSSSKGEGKYARQTGGKGQYGHVIIEMEPAEVGKGFEFVNKIVGGAVPKEYIGPASNGMKETCESGVLAGYPLIDVKVTLVDGSFHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEPMMKVEVESPDDFLGSVIGDLSSRRGQVEGQSVDDGLSKVQAKVPLAEMFGYATQLRSMTQGRGIFSMEFANYEEVPRNVAEAIITKNQGNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_DESRM
Sequence: MKEKIHPNYQEVEVKCVCGNTFKTGSTKKEIKVEICSNCHPFYTGAQRQIEVGGRAEKFRKKYGLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: GP7D_CHLTH
Sequence: MGSMAFHKSRLFLTFGDASEIWLSTLSHLTRKNYASGINFLVSLEILDLSETLIKAISLDHSESLFKIKSLDVFNGKVVSEASKQARAACYISFTKFLYRLTKGYIKPAIPLKDFGNTTFFKIRDKIKTESISKQEWTVFFEALRIVNYRDYLIGKLIVQGIRKLDEILSLRTDDLFFASNQISFRIKKRQNKETKILITFPISLMEELQKYTCGRNGRVFVSKIGIPVTTSQVAHNFRLAEFYSAMKIKITPRVLRASALIHLKQIGLKDEEIMRISCLSSRQSVCSYCSGEEVSPLVQTPPIL
What are the official names of this protein?
Virulence plasmid integrase pGP7-D, Protein P-11.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: RBN_ECO24
Sequence: MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQHQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVETALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPLEHPLECYGYRIEEHDKPGALNAQALKAAGVPPGPLFQELKAGKTITLEDGRQINGADYLAAPVPGKALAIFGDTGPCDAALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGMLIITHVSSRYDDKGCQHLLRECRSIFPATELANDFTVFNV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: Y452_BUCAI
Sequence: MLFIKIEIIAKTLLIINKKYTEIKMDELNVVNNINHAGTWLIRNQELLLRYTINLTSAIIILVVGMFISKIISNGANQVLITRNIDATIAGFLSALMRYIIITFTFIAALGRIGVQTTSVIAILGAAGMAIGLALQGSLSNFAAGVLLVTLRPLKTEEYVDLGSVSGTVLNIHIFYTTLRTLDGKIVVVPNNKIISGNIINYSREPARRNEFIISVSYNSDIDLVIKILRSVIEKEERVIKDKDIIVGLSELAPSSLNFIVRCWSKNHDLNTVYWDLMAKFKKELDKNNINIPFPQLDVHVYKKK
What are the official names of this protein?
Uncharacterized MscS family protein BU452.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPF_NEPOL
Sequence: MFHFLALTPLAHSEGFGLNTNILETNILNLAAVFALLAYVGTDFVSSLLKTRKESILKSLRDADERYQDAVNQLKQALQELETARTNAAEIRRQSEINAEAIRQRLELLTQEEMARLEEAKETIIKLEEEKAVAEVCTKVISMALVRAEKKIISSMDEAMHRRVMDMYLNLLREVY
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y2912_VIBVU
Sequence: MAASCPCGSNRTYALCCKIAHKHHANVITPEQLMRSRYSAHVLGLVDYVVNTYHPSCHAEEQREGIAESIENDWCKLEVVKAEVGSNENEGFVEFNAYFDEDGKRYCMTERSRFVKEDGLWYYIDGTFPEDEPEPDPRLNQSVSSLKVGRNDPCICGSGKKFKKCCG
What are the official names of this protein?
UPF0225 protein VV1_2912.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: LIPT2_XENTR
Sequence: MSVPVLRVRRLGLVGYAEALGVQGRYVRELKAGGEAGSPGGALLLCEHPAVYTVGVRRGRYPGEEEARLRGLGADFQRTDRGGLITFHGPGQLVCYPVLHLGALRRSLRSYVCGLESAVIRLCRGLGLPGERQPDTGVWVRGNKICAIGVHCARHITSHGLALNCNTDLGWFGHIVPCGIVGKGVTSLTQELGRQVTIDDIIAPFLEAFEEEFQCQLVPEQNPEQNPVQNRPDRDAGPL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes, which catalyze essential redox reactions (By similarity).  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
What are the official names of this protein?
Putative lipoyltransferase 2, mitochondrial, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIS4_CHLPB
Sequence: MLIIPAIDIKDGKCVRLTRGEFDKKKIYLDNPRDMAIIWRKQNAKMIHIVDLDAALTGKLVNFEKIREIVTDLDIPVQVGGGLRSVDAVEKYLDIGVSRVVIGSAAVTNPGLVEDLLKRYSPSQIVVGIDAENGIPKIKGWTESSGMQDYELALQMKKLGVKRIIYTDIACDGMMQGVGFESTKRFVEKAGMRVTASGGVTGSEDLRKLQTLEKYGVDSVIIGKALYENNFSCQKLWYNFEKCIGIDCDFSTALKKECCS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_RHIE6
Sequence: MPKMKTKSSAKKRFKITATGKVKAAAAGKRHGMIKRTNKFIRDARGTMVLAEPDGRKVIKNYLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: DEN1A_HUMAN
Sequence: MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKDPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPAPPDRAASIDLLEDVFSNLDMEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTLQPSAPQQARDPFEDLLQKTKQDVSPSPALAPAPDSVEQLRKQWETFE
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form.  Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PubMed:20154091, PubMed:20937701).  Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P (By similarity).
What are the official names of this protein?
DENN domain-containing protein 1A, Connecdenn 1, Connecdenn, Protein FAM31A.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Presynaptic cell membrane. Note=Associates to membranes via lipid-binding activity.
Protein: MYG_NYCCO
Sequence: MGLSDGEWQSVLNVWGKVEADLAGHGQEILIRLFTAHPETLEKFDKFKNLKTPDEMKASEDLKKHGVTVLTALGGILKKKGQHEAEIKPLAQSHATKHKIPVKYLEFISGAIIHVLQSKHPGDFGADAQGAMSKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ACP_YERPN
Sequence: MSTIEERVKKIIVEQLGVKEDEVKNSASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDFINANQQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_HAEIN
Sequence: MPDIKLFAGNATPELAKRISERLYISLGDATVARFSDGEIQVQINENVRGADVFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADLLSIVGIDRVLTCDLHAEQIQGFFDVPVDNVFGSPVLIHDILKKSDLKNPIVVSPDIGGVVRARAVAKLLNDTDMAIIDKRRPRANVAQVMHIIGDVADRDCILVDDMIDTGGTLCKAAEALKERGAKRVFAYATHAVFSGAAAKNLASDAIDEVVVTDTIPLSEEMKAIGKVRVLTLSSMLAEAIRRISNEESISAMFN
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_CUTAK
Sequence: MTTCFVLASKSPARLRMLRSAGIEPVVIASGADESHLRGEDAVAMTARLSRLKAHSVIESGALEEYPADRMIVVACDSVLNLDGRILGKPHTAERARQWWRRMRGHQGVLVSGHHVAVIVNGQLREQTRIGQTVVTFADLTDAEIDAYVDSGEPAAVAGAFTIDGLGGAFITRINGDPHNVTGISLPLLRQMLMDLDVEWSSLWNGPKGGHLS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAS5_SYNY3
Sequence: MDGLFAPIPSNPLIDFTILLLVTLILPPIFERLKLPGLVGLLFAGIVLGKSGLGVLNEDSESIKLFTDIGKIYLMFVAGLEIDMVDFRRTRNRSLLYGSLTFAVPLLTGLAVGLTFGYSFNASVLLGSLFASHTLLGYPIVQRLGIVRNQAVMVTIGATIFTDIAALLVLAICISIHSGSFSPAGLVVQLVAIAVYSALVLIGFDWAGREYFRRTGDEQSNQFLFVLLAVFLASVGSELINVDKIVGAFLAGLAVNDVLGNSPVKEKVEFLGTTLFIPFFFIGIGLLLDLPAFLVTLTTLFPLVVAIVVGLILSKGVAAILAQWKLGYTWVEGLTMWSLSIPQVAATLAAAVAGYQAVNAAGDRLVSETVLNTIIVLMLITSIVGPLMTAKFAPKIPIPNTLSSLTEDLDDPEENGAVTLIPPKASTFTVLVPTQNPQTLSYLLEMGALIARHESGVVIPLAIAKAPVHMDDPGLTSRLARNELLLQQATELATNLKVDAHPALRIDDDVARAISHTAREKNADLIIMGWSQQTLGLRAKLFGSTIDSVFWSAHCPVAVMRLLSDPRSFHRILFPIKNLTPQTLELFQFTQRLAETNGAIVTLLHVCPHNTSPQQVQAFKTEMERFLNQCRATADYPIKVICHDDAAKVLVRVSHTFDLVVLRSFRRRSVGGVALGEVTDKILREITSSFVLFGDPYA
What is the function of this protein?
Na(+)/H(+) antiporter.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaS5, Sodium/proton antiporter NhaS5.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: QUEA_FRATF
Sequence: MKTDDFDYKLPEELIASYPLENRDASRLLKLNKQTGEIADYKFTDFIDFINPGDLLVFNNSKVMLARLYGSKTTGAKLEYLIERIKNPKLFETHIKANRSPAIGSEIYVEDTLAKVLDKDGGMYLLEIQGDKDIYQLMEEFGHIPLPPYMKRDDEEFDAERYQTVYAQDLGSVAALTAGLHFSKELMQQIKDKGVDIAYITLHVGSGTFKPVQVDDVESHKMHAEVISVPVEVCQKIRQTKENGGRVITIGTTSVRSLETAGQNGQIEPYQGETDIFLYPGKKFNVVDAMITNFHLPKSTLIMLVSAFADKEKIIKAYEHAIAERYRFFSYGDAMFIF
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_LACDB
Sequence: MATHDSKQLEILQYIYDTVENRGFPPTVREICAAVGLSSTSTVHGHLTRLERKGYLIKDATKPRALEITHAGLDALGIKPKDIPVIGVVTAGQPILAVQDVEDYFPLPPNLASDAGELFMLRVHGTSMINAGILNGDYVIVRKQTTAQNGEIVVAMTDDGEATVKRFFKEDLHYRLQPENDAMDPIILNHVQILGKVVGLYRTNID
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ISPG_BURM9
Sequence: MFGGHAPRRVSHAVDVRWGGTLVTIGGAAPVRVQSMTNTDTADAIGTAIQVKELANAGSELVRITVNTPEAAAAVPAIREQLDRMGVTVPLVGDFHYNGHLLLRDYPDCAQALSKYRINPGNVGQGAKRDSQFAQMIEAAIKYDKPVRIGVNWGSLDQDLLARMMDENGARAEPWEAQSVMYEALIQSAIGSAERAVELGLGRDKIVLSCKVSGVQDLVAVYRELSRRCGFALHLGLTEAGMGSKGIVASTAAIGLLLQEGIGDTIRISLTPEPGAPRTGEVVVGQEILQTMGLRSFAPMVVACPGCGRTTSTLFQELALRIQTYLREQMPVWRSEYPGVEKMNVAVMGCIVNGPGESKHANIGISLPGSGENPAAPVFVDGEKVKTLRGEHIAEEFQQIVSDYVARTYGRAAAQN
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: YBEY_NITOC
Sequence: MSITVHIQYAVPKASVPLQADFLRWVKAALVNQSKAGEITIRVASESEAAQLNWRYRHKEGATNILSFPFEVPSCVSLDVPLLGDLVICAPVVAREALEQTKKEQAHWAHLVVHGVLHLLGFDHQQEVEAQQMESLEVTILESLGYPDPYESV
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_BACC7
Sequence: MTGQLVQYGRHRQRRSYARISEVLELPNLIEIQTSSYQWFLDEGLREMFQDISPIEDFTGNLSLEFIDYSLGEPKYSVDECKERDVTYAAPLRVKVRLINKETGEVKEQDVFMGDFPLMTETGTFVINGAERVIVSQLVRSPSVYYSGKVDKNGKRGFTATVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQEITELLGDNEYLSNTLEKDNTDSTEKALLEIYERLRPGEPPTVENAKSLLVSRFFDPKRYDLANVGRYKINKKLHIKNRLFNQRLAETLVDPETGEILAAEGTILDRRTLDRILPYLEKNIGFKTAKPMGGVVEGDVELQSIKIYAPESEGERVINVIGNANITRDVKHITPGDILASISYFFNLLYKVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTNAITPQALINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSFAKVNEFGFIETPYRRVDPETGLVTGHVDYLTADEEDNYVVAQANMKLSEEGEFLDEDIVARFRGENIVTNKERIDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPESPIVGTGMEYVSAKDSGAAVICKHPGIVERVEAREVWVRRYVEVDGQTVKGDLDRYKMQKFIRSNQGTCYNQRPIVSVGNEVVKGEILADGPSMELGELALGRNVLVGFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVGEDALRNLDERGIIRVGAEVKDGDLLVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGGGGIILDVKVFNREDGDELPPGVNQLVRAYIVQKRKISEGDKMAGRHGNKGVISRILPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQVLELHLGMAARYLGIHIATPVFDGAREEDVWGTIEEAGMANDAKTILYDGRTGEPFDNRVSVGVMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGENVPEPGVPESFKVLIKELQSLGMDVKMMSSDDTEIEMRDTEDDDDHQSADKLNVEVETTKE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: METB_HAEIN
Sequence: MTQQYAIDTLLAQAGNRSDERTGAVSAPIFLSTAYGHCGIGESTGFDYTRTKNPTRTVLEETIAKLENGDRGFAFSSGMAAIQVLMTLFTAPDEWIVSSDVYGGTYRLLDFSYKNNNSVKPVYVNTASASAIEAAINPNTKAIFIETPSNPLMEECDVVEIAKLAKKHNLMLIVDNTFLTPVLSRPLDLGADVVIHSGTKYIAGHNDALVGLIVAKGQELCDRIAYIQNGAGAVLSPFDSWLTIRGMKTLSLRMKRHQENAQAIAEFLKAQPQVESVLYPNKGGMLSFRLQDEAWVNTFLKSIKLITFAESLGGTESFITYPATQTHMDIPESERVARGITNTLLRFSVGIEDVEDIKADLLQAFANLK
What is the function of this protein?
Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction.  In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity).
What are the official names of this protein?
Cystathionine gamma-synthase, CGS, O-succinylhomoserine (thiol)-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_CLOPS
Sequence: MLMPKRVKHRKVQRGRMKGKATRGNFLAYGDFGIQATTCGWITSNQIEAARIAINRYIRRGGKLWIKIFPDKPVTEKPAETRMGSGKGSVEYWVAVVKPGRVLFELSGVDEEKAREAMRLASHKLPVKTKFVTRRDFEEMGGEE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PTKA_ECOLI
Sequence: MTNLFVRSGISFVDRSEVLTHIGNEMLAKGVVHDTWPQALIAREAEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVHFQQADDDNDVAVSLVIALIVENPQQQLKLLRCLFGKLQQPDIVETLITLPETQLKEYFTKYVLDSDE
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.  The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport.  It can also use D-glucitol.
What are the official names of this protein?
PTS system galactitol-specific EIIA component, EIIB-Gat, Galactitol-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGK_SALTY
Sequence: MYYGFDIGGTKIALGVFDSTRRLQWEKRVPTPHTSYSAFLDAVCELVEEADQRFGVKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLVLNGKPITGQSYITGEFGHMRLPVDALTLMGFDFPLRRCGCGQMGCIENYLSGRGFAWLYQHYYDQSLQAPEIIALWEQGDEQAHAHVERYLDLLAVCLGNILTIVDPDLLVIGGGLSNFTAITTQLAERLPRHLLPVARAPRIERARHGDAGGMRGAAFLHLTD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.