PharMolix/UniProtQA huggingface dataset:
Protein: ZN140_HUMAN
Sequence: MSQGSVTFRDVAIDFSQEEWKWLQPAQRDLYRCVMLENYGHLVSLGLSISKPDVVSLLEQGKEPWLGKREVKRDLFSVSESSGEIKDFSPKNVIYDDSSQYLIMERILSQGPVYSSFKGGWKCKDHTEMLQENQGCIRKVTVSHQEALAQHMNISTVERPYGCHECGKTFGRRFSLVLHQRTHTGEKPYACKECGKTFSQISNLVKHQMIHTGKKPHECKDCNKTFSYLSFLIEHQRTHTGEKPYECTECGKAFSRASNLTRHQRIHIGKKQYICRKCGKAFSSGSELIRHQITHTGEKPYECIECGKAFRRFSHLTRHQSIHTTKTPYECNECRKAFRCHSFLIKHQRIHAGEKLYECDECGKVFTWHASLIQHTKSHTGEKPYACAECDKAFSRSFSLILHQRTHTGEKPYVCKVCNKSFSWSSNLAKHQRTHTLDNPYEYENSFNYHSFLTEHQ
What is the function of this protein?
May be involved in transcriptional regulation as a repressor.
What are the official names of this protein?
Zinc finger protein 140.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FUR_STAAR
Sequence: MNTNDAIKILKENGLKYTDKRKDMLDIFVEEDKYINAKYIQQVMDENYPGISFDTIYRNLHLFKDLGIIENTELDGEMKFRIACTNHHHHHFICEKCGDTKVIDYCPIDQIKLSLPGVNIHKHKLEVYGVCESCQD
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_STRP2
Sequence: MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGLSVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLHVLKLSKIYREGNGSEKETKVD
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: XERCL_CALS4
Sequence: MAKKTNYVKNGKEYYRVTVTIGRDENGKLIRKEFYGKTKKEAEAKKEEYLNGIRNGLNVDFQDVTLGDLMHTWLFEVVRMSRKPATFVKYEGHYRNYIKNSELYGMKISIIKSIQIQRYYNKLYQQGKSSKTIKALNNFLKTFFNYAVDEGYLAKNPCTGKKIVIPGTPEEKIETEIETFSDEEIKKIKEALKGHRLKALFLLAFGTGLRQGELLGLKWTDIDFEKKELRVQRMIKQVTIIDEKGNRKYKTIEQIPKTKNSIRTVPIPSSLIPMLKEHRNRQREEKLKAGSVYLNDVEKGYVFTTELGNTIDASNLLKTYKKILNRAGVPYRKFHAIRHTYATKLFERGVPLKTVSELLGHSNISITANIYTHVIPKQKTNAVETLNDLFI
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
What are the official names of this protein?
Tyrosine recombinase XerC-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_AFIC5
Sequence: MTKTIYVLNGPNLNLLGTREPDIYGHHTLADVEALCRETAARFGLEAVCHQTNREGEIVDLIHEAAKKQAAGLIINGGGYSHTSVAIHDAIVGVQIPTVEVHVSNVYARERFRHQSFIAKAAFATLCGFGIEGYRLAILGLAARIGLAAKT
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: TSAD_CORGL
Sequence: MIVLGIESSCDETGVGVVKLDGEGNLEILADSVASSMQEHARFGGVVPEIASRAHLESMVPVMREALRQAGVDRPDAVAATVGPGLAGALLVGASAAKAYAAAWGVPFYAVNHLGGHVAVANLEGETLPHAVALLVSGGHTQLLEVDAVGLPMKELGSTLDDAAGEAYDKVSRLLGLGYPGGPIIDKLARRGNPEAIAFPRGLMKKSDSRHDFSFSGLKTSVARYVEAAERNGEVISVEDVCASFQEAVCDVLTFKAVRACRDVGAKVLLLGGGVAANSRLRELAQERCDKADIELRVPRFNLCTDNGVMIAALAAQRIHEGAQESPISVGTDPSLSVETPQVF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBAB_ECOHS
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RECR_SHELP
Sequence: MKFSPLVDELIQSLRCLPGVGPKSAQRMAFQLLERDRKAGHKLAQALSSAMSDVGHCSSCRTFTEESLCPICASSRRGNSDLICVVETPADVLAIEAGGHFSGRYFVLLGHLSPLDGVGPDELGLSLLETHLASGEVSELILATNPTVEGDATAHFIADMAKQHEVNVSRIAHGVPVGGELEYVDSTTLALSFNGRIPL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MURA_BACTN
Sequence: MASFVIEGGHRLSGEIHPQGAKNEVLQIICATLLTAEEVTVNNIPDILDVNNLIQLMREMGVTVAKEGIDTYSFKAENVDLAYLESDKFLKKCSSLRGSVMLIGPMVARFGKALISKPGGDKIGRRRLDTHFVGIQNLGADFRYDESRGIYEITADRLQGSYMLLDEASVTGTANILMAAVLAKGTTTIYNAACEPYLQQLCRMLNRMGAKISGIASNLLTIEGVEELHGTQHTVLPDMIEVGSFIGMAAMTKSEITIKNVSYENLGIIPESFRRLGIKLEQRGDDIYVPAQETYEIESFIDGSIMTIADAPWPGLTPDLLSVMLVVATQAKGSVLIHQKMFESRLFFVDKLIDMGAQIILCDPHRAVVIGHNHGFKLRGARLTSPDIRAGIALLIAAMSAEGTSTISNIEQIDRGYQNIEGRLNAIGARITRI
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLI3_HUMAN
Sequence: MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITMQPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFAMDPRNGYMEPHYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRGLSPTDAPHAGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAGQQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQGYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVVRGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYSGQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLLTSLAEESKFLAVMQ
What is the function of this protein?
Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development.  The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor.  A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity.  In concert with TRPS1, plays a role in regulating the size of the zone of distal chondrocytes, in restricting the zone of PTHLH expression in distal cells and in activating chondrocyte proliferation.  Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
What are the official names of this protein?
Transcriptional activator GLI3, GLI3 form of 190 kDa, GLI3-190, GLI3 full-length protein, GLI3FL.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium. Note=GLI3FL is localized predominantly in the cytoplasm while GLI3R resides mainly in the nucleus. Ciliary accumulation requires the presence of KIF7 and SMO. Translocation to the nucleus is promoted by interaction with ZIC1.
Protein: TAPT1_CAEEL
Sequence: MNNVPSTSRENSRNPSESSSSIQDLLINVEANDLSSVVNEDVSITMSAPPSPATPRKIDFSAEIETPKSTGIRRRLTLKDSIGSDLENDPESTPAIRKPSRISYDERLTVICDSQTSSPLQTPSPSQERDSAPFADVFQPKGFFSFFWEELTRGYSLHNDHARFSEKRRKVYAFLRIPLELEQFLTYGLLQCIDAFFYLFTFLPLRFLMSIFGALLRIKRWTSAETCDFLKVVIIVAASMLIREIDSSFLYHQVRSQGVIKLYIFYNMLEVADRLFSSLGQDIFDALLWTANSEKRFSVGYFIRTCGHLIVAILYATLHSFLVILQATTLNVAFNSHNQTVLAIMMSNNFVELKGSVFKKFAKANLFQMACSDVRERFHIFALLFVVMIRNMTAVNWNIDSFTEMIPDIIMVVGCEYFVDWLKHAFITKFNEINAEVYKDFTITIAFDVIRSRDQSAFSDYSDQVSRRMGFIPIPLSIMIIRVLSQTFTLDNWGSCIIFGIGWLLVFAVKICNGVVMLGQACHHVKRFRDIQARAEFELFRKRMVEKKSKSAPNSPRMSLIDFTDVLHQPAAGKGFTVSDMLSQWEELQPSLLSSEIRRSTDRETAVSHLTARSDERTPRRAVSMAHIPRRDRSEPPPAPSMDQDPQLDTEDPVVTENNTNSNSEQASPVKKKTTAAPVTSSASTNTNATSSDELADVTAYKMPEQGVQRIE
What are the official names of this protein?
Protein TAPT1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TAPT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CDK2H_CRIFA
Sequence: MSTLGRYRHVVKLGEGTYGMVYKGTEIQTGRVVAFKRMVVTSDDEGIPGAAIREICLLKELRHNNVVELFEVLFDPPKITMIFELCDCDLKRYMESRPQRLLDANTEMRPILKQIFLGLEYLHGRCVVHRDMKPQNIFVNVRGPDFAAMTALPSSPQQSMRVPHAGGTNGEAGRASANGNEHAPRPTAAEGSVSPWEEAANTKDAPNQLIIKIGDFGLARVEEIPVKKYSHEVVTLWYRSPDVLMSSALYSYPVDIWSMGAIFFEMATSKVLFSGRNEDEQLLRMFWLLGSPTKETWPSMMTYTGTMERLERSSRAAAERQDLTVNGDVYVQQQQLQAQQQQPQQGSSPSHSSSRAPDLLTQLAHKRFYHSESAMQQRRESASSAANSYRLPVELWFDRPLFKEYMAATRCDVSVSPEGIDLLRRCLMYEPNQRITAAEAVHHPYLERVPVPTAGSLDVLISSLMQTMETIHLL
What is the function of this protein?
Serine/threonine-protein kinase (By similarity).  Involved in the control of the cell cycle.  Required for entry into S-phase and mitosis (By similarity).  Probable component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 2 homolog, Cell division control protein 2 homolog, cdc2-related kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF3C4_MOUSE
Sequence: MSEADQALVGPKADEPSPPAEEKDEGGGKEAAADAAPGPSASFRLMVTRREPAVKLQYAVSGLEPLSWSEDHRVSVSTARSVAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKVGSKTEVAECKEKFASSKDPTISQTFMLDRMFNPEGKALPPMRGFKYTSWSPMGCDANGRCLLAALTMDNRLTVQVNLNRLQWVQLVDLTEIYGDRLYETSYRLSKNEAPEGNLGDFAEFQRRHSMQTPVRMEWSSICTTQQVKHNNECRDVSSVLLAVLFENGNIAVWQFQLPFVGKESISSCNTIESGISSPSVLFWWEYEHNNRKMSGLIVGSAFGPVKILPVNLKAVKGYFTLRQPVVLWKEMDKLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTGLHSLPIVSITADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGIAVSPCGAYLAIITTEGMMNGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLIDLVRWKILKDKHIPQFLHEALEKKIESSGVTYFWRFKLFLLRILYQSMQKSPSEALWKPTHEDSKILLVDSPGMGDGEDEQQEEGTSKQGTKAGLQEKSKEGDTEETPEDSLTAGGDTGGREPVEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDEDYDDRTAQVLIGHISKKMNKQTFPERCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSCQSLIYRRCLLHDSIARHPVPEDPDWIKRLLQSPCPFCDSPVF
What is the function of this protein?
Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.  Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3.  May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F.  May be localized close to the A box (By similarity).
What are the official names of this protein?
General transcription factor 3C polypeptide 4, TF3C-delta, Transcription factor IIIC 90 kDa subunit, TFIIIC 90 kDa subunit, TFIIIC90, Transcription factor IIIC subunit delta.
What is the protein family that this protein belongs to?
Belongs to the TFIIIC subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATC_BRUSI
Sequence: MSVDISTVKRVAHLARIAVSEDDAERMTGELNAILGFVEQLNEVDVEGIEPMTSVTPMKMRMREDKVTDGGIAAAVVANAPVTEDNFFVVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: TAF13_DICDI
Sequence: MSTKRKRMFSKELKHMMYGFGDVREPLHESIDLLEELVFEFIQEMTLKAAQVSNKRGKFQTEDLVFLVRKDPKKYYRVIELLRMNEELKKAKKAFDETNVEEEENV
What is the function of this protein?
TFIID beta-specific TAFII.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 13, TBP-associated factor 13.
What is the protein family that this protein belongs to?
Belongs to the TAF13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROB_YERPN
Sequence: MSGSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQQHAKGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQMLLTRADLEDRERFLNARDTMNALLDNRIVPVINENDAVATAEIKVGDNDNLSALAAILASADKLLLLTDQAGLYTADPRNNPEAELIREVHGIDDVLRGMAGDSVSGLGTGGMATKLQAADVACRAGIDVVIAAGSQVGVIADVIDGTPVGTRFHSLETPLENRKRWIFGAPPAGEITVDDGAVFAIMERGSSLLPKGIRSVKGDFSRGEVIRIRNLNGRDLAHGVSRYNSDALRMLAGHHSQQISEILGYEYGPVAVHRDDMIVS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLXL1_ARATH
Sequence: MSGRNRGPPPPSMKGGSYSGLQAPVHQPPFVRGLGGGPVPPPPHPSMIDDSREPQFRVDARGLPPQFSILEDRLAAQNQDVQGLLADNQRLAATHVALKQELEVAQHELQRIMHYIDSLRAEEEIMMREMYDKSMRSEMELREVDAMRAEIQKIRADIKEFTSGRQELTSQVHLMTQDLARLTADLQQIPTLTAEIENTKQELQRARAAIDYEKKGYAENYEHGKIMEHKLVAMARELEKLRAEIANSETSAYANGPVGNPGGVAYGGGYGNPEAGYPVNPYQPNYTMNPAQTGVVGYYPPPYGPQAAWAGGYDPQQQQQQQPPPQGQGHR
What is the function of this protein?
Has no transcriptional activation activity.
What are the official names of this protein?
Protein FLX-like 1, AtFLXL1.
What is the protein family that this protein belongs to?
Belongs to the FLX family.
Protein: KDPA_STRGG
Sequence: MSSQVAGLLQLTALIAALALAYRPLGDYMARVYSSEKHYRPEKWMYKAIGANPAAEMRWPAYLRGVLAFSAMSVLFLYLMQRVQGSLPGSLGFSSIDPDQAFNTAASFVANTNWQSYYGEQAMGHVVQTGGLAVQNFLSAAVGMAVAVALVRGFARSRTGELGNFWADLVRGTVRILVPISVIGAIVLVAAGAIQNFSGIHQVGQFAGGTQEWNGGAVASQEAIKELGTNGGGYFNANSAHPFENPNPLSNLFEVFLILLIPFALTRTFGRMAGSLKQGYAILGAMAVIWIGFTALMMWTEFAHRGPAFEIAGGAMEGKEARFGIAGSSIFAVATTLTSTGAVNSFHSSYTGFGGGITLLGMQLGEIAPGGVGSGLYGMLIMAIIAVFIAGLMVGRTPEYLGKKIGTRQIKFAACYILITPALVLGFTAVAMALPTPADSMTNSGAHGFSEILYAYTSGANNNGSAFAGLNADTQWFNTTIGIAMLLGRFLPMVFVLALAGSLAEQQPVPETAGTLRTDKPLYSGLLVGTILIITGLTYFPALALGPLAEGLAS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y191_METTH
Sequence: MCGIAGVVYKDGKLHSVGADMTRMLHALQHRGPDSAGFAIYGGLGLEENDYLLNIEVKDKPGLLDMVKETVELVSPIGSDEVIPSVENHIIYRCRITLESFSQLKPLIMDIDSIDDVIVLNGSHSFEMIKDVGSVLEIADRYDTWSKKGTHAIGHTRFSTESIVDRYHAHPFQSYIIPDITVVHNGQITNYWKIREPLERKGHIFETNNDTECIVHYVADKLASGYSLEEALEQSVKDMDGPFSYIVGTPQGVGIAKDQLGLRPGVMAENDEVFAVASEEVSLREVMDTSEVEQISPGEVRVYEI
What are the official names of this protein?
Putative glutamine amidotransferase MTH_191.
Protein: RL4_HALH5
Sequence: MPKVALYNQAGSQVGDIELSDAVFGIEPNENVLHDAVVMQQASLRQGTHKTKTRSEVRGGGRKPWRQKGTGRARQGSIRSPQWVGGGTVFGPTPRSYSYKLPKKVRRLAIKSALSSKVKAEEIVVLESLALEAPKTKEMASILSGLSVDRKALVVTADYNDNVALSARNIPGVTFVTAEGVNVLDVIKHDKLIITKDAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RIMM_MYCUA
Sequence: MELVIGRVVKAHGITGEVVVEIRTDEPDRRFTPGASLRAKRSRDGGTGRNYVIEGVREHGARLLVRLAGVNDRDTADGLRGSLFVIDSADLPPIEEPDTYYDHQLEGLRVRTTAGQDVGVVAEVLHTGAGELLAVKCDSGEVLVPFVGAIVTSVSLDDRILEIDPPDGLLDLGS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCAF_PSEAE
Sequence: MSREVFICDAVRTPIGRFGGSLSAVRADDLAAVPLKALVERNPGVDWSALDEVFLGCANQAGEDNRNVARMALLLAGLPESVPGVTLNRLCASGMDAIGTAFRAIACGEMELAIAGGVESMSRAPYVMGKADSAFGRGQKIEDTTIGWRFVNPLMKEQYGIDPMPQTADNVADDYRVSRADQDAFALRSQQRAGRAQEAGFFAEEIVPVTIRGRKGDTLVEHDEHPRPDTTLEALARLKPVNGPEKTVTAGNASGVNDGAAALVLASAEAVEKHGLTPRARVLGMASAGVAPRIMGIGPVPAVRKLLRRLDLAIDAFDVIELNEAFASQGLACLRELGVADDSEKVNPNGGAIALGHPLGMSGARLVLTALHQLEKSGGRRGLATMCVGVGQGLALAIERV
What is the function of this protein?
Catalyzes thiolytic cleavage of beta-ketoadipyl-CoA to succinyl-CoA and acetyl-CoA.
What are the official names of this protein?
Beta-ketoadipyl-CoA thiolase, 3-oxoadipyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: FPG_RHOPB
Sequence: MPELPEVETVRRGLEPAMAGARIDGFEARRADLRFALQPDLATRLIGQTVKGLGRRAKYLLAELSSGDVLLMHLGMSGSFRVLQGEASGAPGAFHHPRNDDRAHDHVVFRMSNGAVVVFNDPRRFGYMKILAPGEIADEPFLKGLGPEPLGNSFDAAMLASACAGRKTSLKAALLDQRVVAGLGNIYVCEALFGAHLSPKRLAATLATRTGAPTERAERLVEAIRAVLHAAIKAGGSSLRDHRQTSGELGYFQHSFAVYDREGEPCRSKGCDGVVKRFVQNGRSTFWCPKCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SUFE_KLEP3
Sequence: MAALPDKDKLLRNFSRCANWEEKYLYIIELGQRLAPLSPEEYSVQNIIQGCQSQVWIVMAQDPSGIITLRGDSDAAIVKGLIAVVFILYDRMTAQDIIEFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAANIS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYG_LEPMU
Sequence: MGLSDGEWQLVLNVWGKVEADVGGHGQEVLIRLFTGHPETLEKFDKFKHLKTADEMKASEDLKKHGTTVLTALGGILKKKGQHEAELKPLAQSHATKHKIPIKYLEFISDAIVHVLHSKHPAEFGADAQAAMKKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL20_ACTP7
Sequence: MARVKRGVIARARHKKVLKAAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGLSYSKFINGLKKVSVEIDRKILADIAVFDKVAFAALVEKAKSAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TDH_XANOM
Sequence: MKALVKRETNKGIWLEQVPVPTPGPNEVLIKLEKTAICGTDLHIYLWDEWSQRTIKPGLTIGHEFVGRVAELGSAVTGYQVGQRVSAEGHIVCGHCRNCRGGRPHLCPNTMGIGVNVNGAFAEYMVMPASNLWPIPDQIPSELAAFFDPYGNAAHCALEFDVIGEDVLITGAGPIGIIAAGICKHIGARNVVVTDVNDFRLKLAADMGATRVVNVSKTSLKDVMADLHMEGFDVGLEMSGNPRAFNDMLDCMYHGGKIAMLGIMPRGAGCDWDKIIFKGLTVQGIYGRKMYETWYKMTQLVLSGFPLHKVLTHQLPIDDFQKGFDLMEAGKAGKVVLSWN
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.