PharMolix/UniProtQA huggingface dataset:
Protein: PDE6B_BOVIN
Sequence: MSLSEGQVHRFLDQNPGFADQYFGRKLSPEDVANACEDGCPEGCTSFRELCQVEESAALFELVQDMQENVNMERVVFKILRRLCSILHADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVQDVMECPHFSSFADELTDYVTRNILATPIMNGKDVVAVIMAVNKLDGPCFTSEDEDVFLKYLNFGTLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQAYSGPRTPDGREILFYKVIDYILHGKEDIKVIPSPPADHWALASGLPTYVAESGFICNIMNAPADEMFNFQEGPLDDSGWIVKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDREEIQLILPTRERLGKEPADCEEDELGKILKEVLPGPAKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVLVRFLFSVSKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDESKNYEDRKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEDQKKETTAKKVGTEICNGGPAPRSSTCRIL
What is the function of this protein?
Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP (By similarity).  Necessary for the formation of a functional phosphodiesterase holoenzyme (By similarity).  Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock (By similarity).  May participate in processes of transmission and amplification of the visual signal (By similarity).
What are the official names of this protein?
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, GMP-PDE beta.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Cell projection, cilium, photoreceptor outer segment.
Protein: YGGU_ECO45
Sequence: MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN
What are the official names of this protein?
UPF0235 protein YggU.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: CPFR5_XENRU
Sequence: GFGSFLGKALKAALKIGANALGGAPQQ
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Caerulein precursor fragment R5, CPF-R5.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL3_ECOLI
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of two assembly initiator proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, Large ribosomal subunit protein uL3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CER1_ARATH
Sequence: MATKPGVLTDWPWTPLGSFKYIVIAPWAVHSTYRFVTDDPEKRDLGYFLVFPFLLFRILHNQVWISLSRYYTSSGKRRIVDKGIDFNQVDRETNWDDQILFNGVLFYIGINLLPEAKQLPWWRTDGVLMAALIHTGPVEFLYYWLHKALHHHFLYSRYHSHHHSSIVTEPITSVIHPFAEHIAYFILFAIPLLTTLLTKTASIISFAGYIIYIDFMNNMGHCNFELIPKRLFHLFPPLKFLCYTPSYHSLHHTQFRTNYSLFMPLYDYIYGTMDESTDTLYEKTLERGDDIVDVVHLTHLTTPESIYHLRIGLASFASYPFAYRWFMRLLWPFTSLSMIFTLFYARLFVAERNSFNKLNLQSWVIPRYNLQYLLKWRKEAINNMIEKAILEADKKGVKVLSLGLMNQGEELNRNGEVYIHNHPDMKVRLVDGSRLAAAVVINSVPKATTSVVMTGNLTKVAYTIASALCQRGVQVSTLRLDEYEKIRSCVPQECRDHLVYLTSEALSSNKVWLVGEGTTREEQEKATKGTLFIPFSQFPLKQLRRDCIYHTTPALIVPKSLVNVHSCENWLPRKAMSATRVAGILHALEGWEMHECGTSLLLSDLDQVWEACLSHGFQPLLLPHH
What is the function of this protein?
Aldehyde decarbonylase involved in the conversion of aldehydes to alkanes.  Core component of a very-long-chain alkane synthesis complex.  Involved in epicuticular wax biosynthesis and pollen fertility.
What are the official names of this protein?
Very-long-chain aldehyde decarbonylase CER1, Protein ECERIFERUM 1.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1867_FRAP2
Sequence: MDHSVLNVLVCPVCNSNLHYDKENQLLICKADKLAYPIRENIPVMLVEEAKKLTLEEVKKYG
What are the official names of this protein?
UPF0434 protein Fphi_1862.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: HVM49_MOUSE
Sequence: MGWSCIMLFLAATATGVHSQVQLQQPGAELVKPGASVKLSCKASGYTFTSYWMHWVKQRPGRGLEWIGRIDPNSGGTKYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYYCAR
What are the official names of this protein?
Ig heavy chain V region 1-72, Ig heavy chain V region VH558 B4.
Protein: CYAY_ACTPJ
Sequence: MNVAEFHQKVEQVWQQIEEKIDDEALSIDTEIHGAVCTLTFDDESQIIINKQEAMLELWLASKLGGFHFAFRDGEWVTAEGRSFWTHLEEAFARHGEQISF
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: HELI1_TNAVC
Sequence: MFKYALPLYPTMEISTESWSLTSLERINSFIEIGNQDEMIYINKDDSTKVFDEIKPMRHQILIGNMMSSRSPVDSLILMHGVGTGKTLTAILSIINNISDTEFGMKRALILTPNRAILSSFKEEVFNCCMHHYGAGFHTNVEHEVRNIINELFKFDTIRSFCNKIAIKSDEIIHKEWNASFIVIDEAHDVAPSGIDYPKLNRFMKILSTRKLLLMTATPMRNGSSDLIPLHNLMMKKQVHDISLEEFHGNYVEINRRRPPSEDGDSIVFSVETPKIAFMTKFAGLISYLPSDALRLDNVNVINVGDNTTYGGVLLSTTNIVSHNMSELMERIYSGLLNDNNNTNRRGDVALLDQRQASRFIFPDGQYGTLGYMAWMNSNTGKATLRFKRELRFGSNMETVLGAVEKFSPRYANIAKTVYECARRGEKSIVYDDLVTGSGLLVLATILEAIGMKRGSGSNRNSFVCMTREVMTVSQIVAAQRVFNSPENYDGSIISVILGSRVISEGLTFKDVQHEHVVAHWNDSETEQIIGRGIRVGSHSKLLETLNTPVTVKVYRHATIYNREPDKSVDVIMYATSEMKRKNINTITEALRSIAMTCPELESRSISRTICAFTPHEENISNVVPLHHPTIRRTFMDRLNETFNYEKDEYFVTRMENFCSAYNLNYQSDGGMRLMFILLKLIQTTPQLDINKFINCDGYFVYTTKTVDEYNSCRTLRYPFDVSYKSTKRLYYDTIVSLITEPNLIKAYETNPNYPLTKLPLHVITIILEKAISRKLLLTSDDEHQNAYHIQALDTFKQYYHIVYESGGGSNSNSATDIKAVCWLSASVAGESTKYRICVSDQNTWKDCPDDMKEQVNNIKVTKDNTTIFQMREKSLSHYGQKNPFSNDFCLRVIPQNSLSAKYDKRRIASGKKCTTWDNATLGRIKQNLGIESPLLHERTTMSRSDSCKLIESRLEEIDAVVTDVACGVQAKRK
What are the official names of this protein?
Putative ATP-dependent RNA helicase.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
Protein: PEPE_PASMU
Sequence: MKNMLLMSGSKYQNTDYLVHTLPWLQDFLADYQGKTVAFVPYAGVRQSYDEYELKVQKALAELNVAILSVHRAEKHAEIIEKADVIAIGGGNTFCLLKGMYEHHLLPLIREKVQSGTPYFGWSAGANVAGRSIMTTNDMPITYPPSFDALNLFPHQLNPHFISGKPAGHNGESREERLAEFLIVNPTANVYALPEGTALHIQGQQARVLGQHDVLLFSENMQLATLPVNSVFDY
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAZF9_MYCTU
Sequence: MMRRGEIWQVDLDPARGSEANNQRPAVVVSNDRANATATRLGRGVITVVPVTSNIAKVYPFQVLLSATTTGLQVDCKAQAEQIRSIATERLLRPIGRVSAAELAQLDEALKLHLDLWS
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Upon expression in E. coli and M. smegmatis inhibits cell growth and colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin MazE9.  Acts as an mRNA interferase, specifically cleaving between U and C in UAC sequences.  May cleave its cognate antitoxin's gene (PubMed:25608501).  In E. coli expression with non-cognate antitoxins VapB27 and VapB40 partially neutralizes the toxin.
What are the official names of this protein?
Endoribonuclease MazF9, Toxin MazF9, mRNA interferase MazF-mt1.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: YRA2_YEASA
Sequence: MDKAFDEIIGNSHTDSSSNHKVTRYRRRDLRNELGPRLGFAPSDAASRSKDRLYREREEPPLPKRIRISKIPLDVSDYTLDDMIKEFGSPIFSKIFDNKEDRTCIYEFEDPEVLEKIVERYNGHELHNAKIEVEIYQPQRKHSRMNAHNRRKQTAQEQGRGRPGSHYRQRPNRVSKKNKGREKNNTPTSVEALDAELDAYMKG
What is the function of this protein?
Involved in export of poly(A) mRNAs from the nucleus.  Recruited to the coding sequences as well as poly-A sites of active genes (By similarity).
What are the official names of this protein?
RNA annealing protein YRA2.
What is the protein family that this protein belongs to?
Belongs to the YRA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DIK1B_XENTR
Sequence: MRKLRRLVHMVLFCPISKGLQSRLPGIKVKYLFLAWLSVFVGSWVVYMHYSSYSELCRGHVCRMIICDQYKKGIISGSACKDLCDERTLVFQQCLSSSPTQQVYSGRWRDREVIIKCGVEETLKADSNPDSPPRRELVLFDKPTRGTSMDEFKEMLGNFLKANLGEQVSLTALVSQILTMADVNNDGKVSLAEAKSIWALLHLNEILLMLSLREKEHTSQLLGHCGDLYVTEKIPHDSLYGSQIPGFLQTLLPSPVHRLVHQWCAPAWPRRAKIAIGLLEFVEEIFHGTYGSFFICDSSFKNIGYNEKYDFKVVDLRKVATEMTIRGFLKGRHCEQNSDCTFGSDCTAACDKLMKQCRNDVIQPNLAKACQLLQDYLLYGSPSDLREELQKQLRTCMTLSGLASQMEVHHSLILNNLKTLLWKKISNTKYS
What are the official names of this protein?
Divergent protein kinase domain 1B, Protein FAM69B.
What is the protein family that this protein belongs to?
Belongs to the DIPK family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: FLICB_PSEAE
Sequence: MALTVNTNIASLNTQRNLNASSNDLNTSLQRLTTGYRINSAKDDAAGLQISNRLSNQISGLNVATRNANDGISLAQTAEGALQQSTNILQRIRDLALQSANGSNSDADRAALQKEVAAQQAELTRISDTTTFGGRKLLDGSFGTTSFQVGSNAYETIDISLQNASASAIGSYQVGSNGAGTVASVAGTATASGIASGTVNLVGGGQVKNIAIAAGDSAKAIAEKMDGAIPNLSARARTVFTADVSGVTGGSLNFDVTVGSNTVSLAGVTSTQDLADQLNSNSSKLGITASINDKGVLTITSATGENVKFGAQTGTATAGQVAVKVQGSDGKFEAAAKNVVAAGTAATTTIVTGYVQLNSPTAYSVSGTGTQASQVFGNASAAQKSSVASVDISTADGAQNAIAVVDNALAAIDAQRADLGAVQNRFKNTIDNLTNISENATNARSRIKDTDFAAETAALSKNQVLQQAGTAILAQANQLPQAVLSLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
B-type flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: HEM3_BACC2
Sequence: MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDDEVITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDAITERTVAAERVFLHKLEGGCQVPIAGYATLKENDTIELTALVGSMDGSVLLKETVVGTNPEEVGLEAAGRLIKQGAKELILAANKEQQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RL11_ACIAC
Sequence: MAKKIVGFIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAQTQGVEPGLPLPVVITAFADKSFTFIIKTPPATTLIKKAIKLEKGSSNALSTKVGKITRAQLEEIAKTKLKDMNAANVDAAVRTLAGSARSMGVTVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SRP54_BUCAI
Sequence: MFNNLTQRLSDSLKKILNKGRLTEENIKETIREVRKALLEADVALSVIKKFIENVKKKSIGHEINKSLTPGQEFIKIVKHELIFAMGEKNHSLNFSIEPPAVILVVGLQGSGKTTSLAKLGKWIKNKYKKKILITSTDTYRAAAIEQLKILSDQIEIDFFESDKHHTPIEITKNAIKYAKLKLYDVLLIDTAGRLHIDKKMMNEIQQIQVISKAIETLLIVDSMMGQDAINMAKIFNNDLLISGIILTKTDGDSRSGIALSMRYITGKPIKFIGTGEKIISLEPFHPERIADRILGMNDIMSLIEDIEEKVDQSQIQKLTKKLKKGHDFNLNDFLTQIKQMKKIGGLNYFANKFSINHQLSNNISLLNTDKNTLKKIEAMICSMTPKERIKPIIIKGSRKRRIALGSGTQIQDVNKLLKNFDDIRRIMKKIKTDGIAKVIRGIKNMLPKKF
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.  Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: EFP_STRPG
Sequence: MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQELLYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVVNVPDFIEAGQKLIINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_LACH4
Sequence: MAKLIVDDLDVKGKKVLVRVDFNVPIKDGVIGDDNRIVAALPTIKYIIEHGGKAILLSHLGRVKSDADKKELSLKPVAERLSELLKKPVTFVPSNEGKEVEDAINNMKDGDVVVLENTRFQDIDNDFGKRESGNDPKLGEYWASLGDMFVNDAFGTAHRSHASNVGIATAMKGNGKLAAAGYLLEKEIKYLGDAVDNPVHPFVTILGGAKVSDKIGVINNLIPKSDHILIGGGMAYTFLAAQGHEIGKSLFEADKVDLAKELLEKAGDKIVLPVDNVAATEFSNDASREVVGDDIPDNMMGLDIGPKTIAKFKDILKDAKTVVWNGPMGAFEMPNFAEGTLEIGRALANLTDATTIIGGGDSTAAAKQLGIAPKISHISTGGGASLNYLEGKVLPGIACVQDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_PHOV8
Sequence: MATAYHNLSDYDFNSVPNAENMRFGIVVSEWNNNITGPLLEGAISTLKKHGAKDKNILVQTVPGSFELTFGSAQMIKSGKVDAVIAIGCVVRGDTPHFDYVCAGTTQGIAQLNAEGDIPVIYGLITTNTMQQAEDRAGGRLGNKGDECAITAIKMLDFKEKLQKTQIF
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: OLF9_CHICK
Sequence: VAICSPLLYSTVMTKRVCMQLVVGSYMGGLLNSLTHTCGLLGLPFCGPNVINHYFCDIPPLLQLACSDTHRNETLLLAFSAVIALFTLFVITASYMLILSVILKIQSDDGRKKTFHTCASHLTAITIFFGS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor-like protein COR9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FBX6_ARATH
Sequence: MEEELAMLRQLIGQLQELLHNGSPPPPSSSSSLSSSSPSFLVLHHPQYQNGWCLPCIEDTSADDCCDIVMAGGKRPGIFKMLETVKPPVKRTRKERTQGKSCTEVDEISGNMDQEIWQEFPQDLFEDVVSRLPMATFFQFRAVCRKWNALIDSDSFSRCFTELPQTIPWFYTITHENVNSGQVYDPSLKKWHHPIIPALPKKSIVLPMASAGGLVCFLDIGHRNFYVSNPLTKSFRELPARSFKVWSRVAVGMTLNGNSTSHGYKVLWVGCEGEYEVYDSLSNVWTKRGTIPSNIKLPVLLNFKSQPVAIHSTLYFMLTDPEGILSYDMVSGKWKQFIIPGPPDLSDHTLAACGERLMLVGLLTKNAATCVCIWELQKMTLLWKEVDRMPNIWCLEFYGKHIRMNCLGNKGCLILLSLRSRQMNRLITYNAVTREWTKVPGCTVPRGRKRLWIACGTAFHPSPTARA
What are the official names of this protein?
F-box only protein 6.
Protein: NEP_I01A1
Sequence: MDSNTVSSFQDILMRMSKMQLGPSSGDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQIRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SYR_SALG2
Sequence: MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLSGIASKVEIAGPGFINIFLEPAFLSEQVQQALTSDRLGVSQPTRQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVGDWGTQFGMLIAWLEKQQQENAGDMALADLEGFYRDAKKHYDEDEAFAERARNYVVKLQSGDTYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMSADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKADIDEQALASAPVIISEDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDVAGLFSGFYEHCPILSAENDAVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_WOLTR
Sequence: MTKGDWEAVIGLEVHAQVSSKTKLFSSSSTEFGAEHNTQVSLVDAAMPGTLPILNYYSIEQAIRTGLALSAEINKSSYFDRKNYFYPDLPQGYQITQFFEPIVKNGRIFINNNKKEVRIARIHLEQDAGKSIHEESKTYVDLNRAGVALMEIVSEPDLRSSEEAAEFMKKLRQILRYIGSCDGDMEKGSLRCDANVSVRPKGSSTFGTRCEIKNLNSICYIMQAIDYEIQRQIEILESGEKISQDTLLFDVSLGKTKVMRNKEDASDYRYFPEPDLLPVEISQDKIDSIRSSLPELPDQKKLRYIRELSINKYDADVITSDKAIANYFEELIKKHDSKLAVTWLTVELFGRLNKAGIDIVSSPIKANALSELLDFIVDGTISARLGKQVFDIMFETGKPASLIIKEQDLKQITDKGQISEIIDKIINDNQDKVQEYQNGKTKLYGFFVGEVMKLTKGKASPDVVNFILSEKLSS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: TSGA_YERPY
Sequence: MNNSNRIRLTWISYLSYALTGALVIVTGIVMGNIAEYFNLPIASMSNTFTFLNAGILISIFLNAWLMEIIPLKRQLVFGFILMLIAIAGLMVGHNLMIFSISMFIFGVVSGITMSIGTFLVTHMYEGRQRGSRLLFTDSFFSMAGMIFPIAAAMLLARHIEWYWVYACIGLLYVGIFVLTLCSEFPVLGHKATDQSKPVVKEKWGVGVLFLAIAALCYILGQLGFIQWVPEYATKTFNMNISQAGQLVSNFWISYMIGMWIFSFILRFFDLQRIVTVLAAMATLAMYLFVSTDNPAYLSYYILALGFVSSAIYTTLITLGSLQTKVSSPKLVNFILTCGTVGTMLTFVVTGPIVANNGVHAALETANGLYLAVFILCLALGFFTKHRSHGHVTH
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARNA_PSEF5
Sequence: MSNKAVVFAYHDIGCAGIEALLNAGYEIAAVFTHADDPKENTFYGSVAQLCARKGIAVHAPEDANHPLWIERIAKLNPDYLFSFYYRNLLSEPLLATASKGAFNLHGSLLPRYRGRAPANWVLVKGETETGVTLHRMVKRADAGAIIAQERVAIERSDTALSLHHKLRDAAASLLRDTLPALAQGKITETAQDESKASYFGRRTAADGKIDWQRPAEELFNLVRAVTQPYPGAFCAVGEHKLIVWSAEVAKGNEGQAPGRVISVDPLRIACGQDSLVITSGQRNANGLFLGGPQLANELGLVDGSLLRGAESGRKPRRTRVLILGVNGFIGNHLSERLLRDDKYDVYGLDIGSDAIERLRSHPNFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKLVRYCVKYNKRVIFPSTSEVYGMCQDKNFDEDTSNLIVGPINKQRWIYSVSKQLLDRVIWAYGAKGLNFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILNLVEGTPIRLFDGGEQKRCFTDIADGIEALARIVDNENDCCNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRGNFPPFAGFRDVESKAFYGAGYQDVEHRKPSIDNAKRLLNWEPTVEMSETIGNTLDFFLREAMLEIADRAKQEAR
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: S35B3_DROPS
Sequence: MGDGQAGSVININGSASGQQAPTSNSPTLTRKSSSSELPPELRILCFDLTHYNQTTQFLLSCAGVFILYILYGYLQELIFTVEGFKPFGWFLTLVQFGYYIGFGLVERRLEAYRSGRRSLWNVEPAPRCIPMKTYLVLAALTLGTMGLSNSSLGYLNYPTQVIFKCCKLIPVLVGSILIQGKRYGPLDFAAASCMCIGLAWFTLADSQMTPNFNLLGVAMISGALLCDAAIGNVQEKAMKEHKAPSSEVVFYSYGLGFVYLFVIMLVTGNFFSGFAFCLEHPLQTFGYGFLFSLSGYLGIQFVLALVRSSGAPIAATVTTARKAVTIAFSFVLFSKPFTVQYLWSGLIVVLGIYLNVYSKKNKLTFADIRSRFKQFGFRLARSPSRKFLVEV
What is the function of this protein?
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi.  PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi.  Essential for viability.  Involved in glycosaminoglycan synthesis and the subsequent signaling.  May be involved in hh and dpp signaling by controlling the sulfation of heparan sulfate (HS) (By similarity).
What are the official names of this protein?
Adenosine 3'-phospho 5'-phosphosulfate transporter 2, PAPS transporter 2, Solute carrier family 35 member B3 homolog.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: NDPA_VIBC3
Sequence: MSLFLSNVILHQLRKNDNDELVVNYRAESLRNDTSTENLVAELHRVFNAKAGKGFGCFKSDSEFQLWLQEMRRGTLPFYEFSQQSAQRLKNELAKYPFADEGILVMAEYQSLATDYLFIGLLPLNQSLKVTEGLDISATDYLDINKMDIVARIDLSSYETDKESKRYLSYIKGRVGRKVADFFLDFLQADIGLDTKQQNQVLMQAVEDFCADAKFEKEEVISYKKQVYEYCNDQIKAGDEVRVQELSGELPPSNEGVNFFDFTREQGYQLEESFPADRSTVRKLTKYVGAGGGLNLSFDSLLLGERVFYDPETDTLTIKGTPPNLRDQLTRLR
What are the official names of this protein?
Nucleoid-associated protein VC0395_A1624/VC395_2154.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: APAH_CELJU
Sequence: MATYAIGDIQGCYEPLQCLLEKIDFDTAKDKLWLVGDLINRGPDSLATLRFLYSIRSSLEVVLGNHDLHLLAVYFGLRKQNKSDTLTPILEAPDAPELIHWLRQQKLMHHDATLGYALVHAGIPPIWSLDKALACAREVEDYLRGPDFKTFLAHMYGNQPSVWDDSLQGQERLRLITNYFTRMRFCSADGELELTTKENAAAAPPGFAPWFSFMQRKTRQDRILFGHWAALEGQVSTANVYALDTGCVWGGYLTAMCLETGALVQCACEA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.