PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_SACD2
Sequence: MSESTTAKPTKKLYIQTHGCQMNEYDSSRMRDLLGASHDMVPTDNPEEADVLLVNTCSIREKAQEKLFHQLGRWKHLKEAKPDLVIGVGGCVASQEGDAISKRAPFVDLIFGPQTLHRLPEMIETPRENGAVVVDISFPEIEKFDNLPEPEADGATAFVSVMEGCSKYCTFCVVPYTRGEEVSRPAVDVLREVTHLASQGVREVNLLGQNVNAYRDDSSGEVIDLAELIAAVADIDGIDRIRFTTSHPMEFTESLIQAYAEIPELVSHLHLPVQSGSDRILSAMKRGHTCLEYKSKLRKIRALRPDISFSSDFIIGFPGETEADFAATMKLIEDIGFDNSFSFIYSPRPGTPAADLPDDTPEQVKKDRLKILQTRIIQQAQEISRRMVGNTERVLVTGYSKKDPGQLSGRTENNRVVNFRCNQPELIGKFADILIEEALPNSLRGVLLGSELDD
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL400_YEAST
Sequence: MNFPDTPVCEMPFFRGDLRDSNHCAFSKSTCIYLLFEPLRYSCIRLIVMFICVAMITCPNSLRFSQYTFLRSYLTLPSCAYFDFLGTHTSRLKLTPVHIPILVLQRKNNRAYPSDMIYDTCTLDFLFRNLCLHKSCSYVWGQIQSSRRFYRKIDHLA
What are the official names of this protein?
Putative uncharacterized protein YLR400W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NPC2_USTMA
Sequence: MHSRFIAVTLASLSLASQAVAWGCIGQDCNQAADQIAFSAPEPASYEGKVKSLAWEPTPGQGWQWSSCGTGDEVVNVESIVVSPDPPVPGQNLTVRAKGTVKDEVSDGTFADVIVKLGLIRLLARRFDVCEQARESNADLQCPLSAGEYELEHTVALPREIPPGKFNVHITGENQDGSNLLCLDLSIQFGFRR
What is the function of this protein?
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
What are the official names of this protein?
Phosphatidylglycerol/phosphatidylinositol transfer protein, PG/PI-TP.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
Protein: TIG1_HUMAN
Sequence: MQPRRQRLPAPWSGPRGPRPTAPLLALLLLLAPVAAPAGSGDPDDPGQPQDAGVPRRLLQQAARAALHFFNFRSGSPSALRVLAEVQEGRAWINPKEGCKVHVVFSTERYNPESLLQEGEGRLGKCSARVFFKNQKPRPTINVTCTRLIEKKKRQQEDYLLYKQMKQLKNPLEIVSIPDNHGHIDPSLRLIWDLAFLGSSYVMWEMTTQVSHYYLAQLTSVRQWKTNDDTIDFDYTVLLHELSTQEIIPCRIHLVWYPGKPLKVKYHCQELQTPEEASGTEEGSAVVPTELSNF
What is the function of this protein?
Inhibitor of the cytoplasmic carboxypeptidase AGBL2, may regulate the alpha-tubulin tyrosination cycle.
What are the official names of this protein?
Retinoic acid receptor responder protein 1, Phorbol ester-induced gene 1 protein, PERG-1, RAR-responsive protein TIG1, Tazarotene-induced gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I47 (latexin) family.
What are the subcellular locations of this protein?
Membrane; Single- pass type III membrane protein.
Protein: ENGB_CUPTR
Sequence: MSLLHQARFFITVNHLRDLPATAVPEVAFAGRSNAGKSTAINILCNQKRLAFSSRTPGRTQHINYFSVAPVKAPDPLAFLVDLPGYGYAEVSGSAKYHWQGLLSDYVQTRQQLAGLILMMDARRPFTDLDCQMVEWFLPTGRPIHVLLTKADKLTNSENAKALRETRKMLQGYAEQLETPVPMTAQLFSSLKRRGIEEAQAVIAGWLNLPEARKAEREPAAANSVPPAVPPASDPAA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HGD_DROME
Sequence: MSEYKYLSGFGSHFSSEDERYPNSLPVGQNSPQVCPYKLYAEQLSGSAFTAPRTENMRTWLYRKLPSAAHLPFQPFKGAEYFSQNWDEQPPNPNQLRWKPFDLPPKDGKNVNFVEGLHTVCGAGDPRSRHGLAIHIYSCNGSMDNSAFYNSDGDFLIVPQQGVLDITTEFGRMSVAPNEICVIPQGIRFAVNVDSPSRGYILEVYDDHFVLPDLGPIGANGLANPRDFETPVAWFDDRDVKDFQVISKFQGRLFVAKQNHTVFDVVAWHGNYVPFKYDLSKFMVINSVSFDHCDPSIFTVLTCPSLRAGTAIADFVIFPPRWSVQEHTFRPPYYHRNCMSEFMGLILGKYEAKEDGFAAGGATLHSMMTPHGPDVKCFEGASNAKLVPERVAEGTQAFMFESSLSLAVTKWGEETCQKLDAAYYECWQALKNNFQITKN
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: CYB_APTAU
Sequence: MAPIIRKSHPLLKIINNSLIDLPSPSNISAWWNFGSLLGICLITQILTGLLLAMHYTADTSLAFSSIAHICRNVQYGWLIRNLHANGASFFFICIYFHIGRGFYYGSYLYKETWNTGIILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFLIAGITLIHLTFLHESGSNNPLGIISHCDKIPFHPYFSLKDILGFTLMLIPLLTLTFFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLTPLLHKSKQRSMAFRPFSQVLFWLLVANLLILTWVGSQPVEHPFIAIGQMASFTYFLILLVLFPMIGALENKMIY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS18_LEPIN
Sequence: MEGKPQRKQNKYKKKVCRFTADPELAKQINYKNIELLERFITNRGKIIPRRITGTSARYQRVLAREIRKARSIGLLPYKVN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HY14_PIG
Sequence: ARYGKSPYLYPLGY
What are the official names of this protein?
Hypothalamic tetradecapeptide.
Protein: PYM1_MOUSE
Sequence: METASTPEATGTGKYIASTQRPDGTWRKQRRVKEGYVPQEEVPVYENKYVKFFKSKPELPPGLSPEATTPVTPSRPEGGETGLSKTAKRNLKRKEKRRQQQEKEAEALSRTLDKVSLGDTAQIPSALQGPQATPLAASDPSDSAATTEKAKKIKNLRKKLRQVEELQQRIQAGEVSQPSREQLEKLARRRVLEEELEDLELGL
What is the function of this protein?
Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.  Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs.  Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated.  Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions (By similarity).
What are the official names of this protein?
Partner of Y14 and mago, PYM homolog 1 exon junction complex-associated factor, Protein wibg homolog.
What is the protein family that this protein belongs to?
Belongs to the pym family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Shuttles between the nucleus and the cytoplasm. Nuclear export is mediated by XPO1/CRM1.
Protein: PCDA7_HUMAN
Sequence: MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination.  Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-7, PCDH-alpha-7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y2138_NITMU
Sequence: MSISDWPEAERPREKLLKNGPAYLSDAELLAIFLRTGIAGKSAVDLARELLKRFRGLTGLFAADQGAFCQVPGMGPAKFAQLQAVLEMARRALEEELKSSDAMDSPGPVRAFLRLSLEGKEHEVFVSIFLDARNRVIATEELFQGTLTQTSVYPREVVKRALHHNAAAVIFAHNHPSGAAEPSHADAVLTQSLKQALLLVDVRVLDHFIVGRGATLSFAEQGLI
What are the official names of this protein?
UPF0758 protein Nmul_A2138.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: NACA_KLULA
Sequence: MSEIAQDSNVSIFSKNEKKARELILKLGLKPIQGVSRVTFKKKDGQIFAIDRPEVYKSQGGNFVVFGEAKVDDFTQRLAKAQESLQQNEGVLPAGQDAVSKDPQSIQADMQAAADSATDKPSADDAVDDAEVDETGLNADDIELVMQQAGVPRAKAAKALKEHDSDIVNAIMALSG
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD2 may also be involved in transcription regulation (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: Y225_RICPR
Sequence: MNKENKKNQDMSIEEILKSIKGIINERKNPIYDNYSADEDILELTDIVNQNEEENLISTKSASEVEEVFRNFTDTIKDKKLNNNFSSKNALEELVIGMLKPELKAWLDKNLPILVKELVEIEIKKLVQYSKRNDSNY
What are the official names of this protein?
Uncharacterized protein RP225.
Protein: 1433S_BOVIN
Sequence: MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEESSEEKGPEVQEYREKVETELRGVCDTVLGLLDTHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPEEPQS
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.  May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53 (By similarity).
What are the official names of this protein?
14-3-3 protein sigma, Stratifin.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway.
Protein: RECR_CAMJJ
Sequence: MVKGLEKFNELVESFANLPTIGKKTAIRLAYHLCINNQIDGMKLAHNIENAIRFIKPCEQCGALSENELCEICSDEERNKNILCIVESPKDILTLEESQSYNGLYFVLDELNEEKLEKLKQIILKLNISELIFALTHSINSDATIFFIEDKFKGLNLTFSKIAQGIPSGVNLENVDLISLNKAMNFRTKI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: GDF8_BOVIN
Sequence: MQKLQISVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACLWRENTTSSRLEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLLELIDQFDVQRDASSDGSLEDDDYHARTETVITMPTESDLLTQVEGKPKCCFFKFSSKIQYNKLVKAQLWIYLRPVKTPATVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPEPGEDGLTPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGEGQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEPA_HELAH
Sequence: MKPTTPTPMKNIRNFSIIAHIDHGKSTLADCLIAECNAISNREMTSQVMDTMDIEKERGITIKAQSVRLNYTLKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANTYIALDNHLEILPVINKIDLPNANVLEVKQDIEDTIGIDCSSVNEVSAKAKIGIKDLLEKIITTIPAPSGDASAPLKALIYDSWFDNYLGALALVRIMDGNINTEQEILVMGTGKKHGVLGLYYPNPLKKIPTKSLECGEIGIVSLGLKSVTDIAVGDTLTDAKNPTSKPIEGFMPAKPFVFAGIYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFGFRVGFLGLLHMEVIKERLEREFSLNLIATAPTVVYEVHLTDNSIKYVQNPSELPPENHIACIKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDKLKSCTKGYASFDYEPIENREANLVKLDVRVAGDIVDALSIIIDKNKAYEKGRALVEAMKELIPHQLFEVAIQASVGNKIIARETIKSVGKNVTAKCYGGDITRKRKLLEKQKEGKKRMKAIGKVELPQDVFLAILKID
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CB23_NICPL
Sequence: MAASTMALSSSSFAGKAVKLSPSSSEITGNGKVTMRKTASKAKPVSSSSPWYGPNRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHCRWAMLGALGCVFPELLARNGVKFGEAVWFKGGSQIFSQGGLDYLGNPSLVHAQSILAIWACQVVLMGAVEGYRVAGEPLGEVVDPLYPGGSFDPLGLAEDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLADPVNNNAWAYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein C, chloroplastic, LHCII type I CAB-C, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: DEGP3_ARATH
Sequence: MSFLCVRTVSRFRSLSRALAPGFLLLHGNAVPKTAVFFRQQSSNTRLFSSYTAPSGVEENNSKSALKNKLPPGKEVSSKDAKEKITTSAIDLALNSVVKVFTVSSKPRLFQPWQITMQSESTGSGFVISGKKILTNAHVVANQTSVKVRKHGSTTKYKAKVQAVGHECDLAILEIDNDKFWEGMNPLELGDIPSMQDTVYVVGYPKGGDTISVSKGVVSRVGPIKYSHSGTELLAIQIDAAINNGNSGGPVIMGNKVAGVAFESLCYSDSIGYIIPTPVIRHFLNAIEESGEDVSFGSINLTYQKMDNDQLRKDFKMSDKMTGILINKINPLSDVHKVLKKDDIILAIDGVPIGNDSSVHFRKKERITFKHLVSMKKPCETALLKVLREGKEYEFNSSLKSVPPLVPKRQYDKSASYYIFGGLVFLPLTKPYIDSSCVSESALGKMPKKAGEQVVIISQILEDDINTGYSIFEDFQVKKVNGVQVHNLKHLYKLVEECCTETVRMDLEKDKVITLDYKSAKKVTSKILKSLKIPSAVSEDLQPKQQNKRSKVPPKSKEH
What is the function of this protein?
Putative serine protease.
What are the official names of this protein?
Putative protease Do-like 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL34_SULIN
Sequence: MPRPALRSRSLRRIYVKLPSGKTAIHYERKKNDISKCAMCKKPLHGVKTNFLHKYGKSEKRPERPFGGYLCSSCLAQLIKAMVRQ
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: CUL5_DICDI
Sequence: MSDQITVDELWAECEQTFEDLFLNLKKGLSRKRYMEIYTKIYNYCSSANEKALIDFYIPKVKVLVAQKAVEIMSRSESYPNDALLLFFRNQWNEWKMSSNVLKNLLSPVNKIHSSDKKTTSSSANQNESVVYSDTLNSWRETAFNPLKNKLSVSLLQIIKNDRTGFSTNLQVLSDSLECYVQLGPEKNKLEIYQSCFEQQFLQETETFYKAESADFIEKNGVCEYMRHVYNRIEQETNRVNQYMPISTLEKLTKILNNVLISNYKEQFASKFLDILIEDKSSDLVMMYSLLSRVNHLTPLKNIFSDFIKSEGLKEIESNLKEAQEKPQVLISILLKIYSRFNIMIKECYGNDTDFTTAMDKSFSILVNENPASYDPKKKESNIPVVLSKFCDQILRKGPHHISDEAELEKKLTEAVCLFKYLPDKDIFMLNYQKMLSKRLVEDLSASEDAETLMINKLKNYQGFDYCTKLTRMITDMRLCKDININFQNHLNEKSLTLPYQFNFYVLTNGSWTLTNKQTATPFKPPSEMLSSITYFESFYKKSYQGRVLTFLYDFSRADVDSRQAKGKIYKLTTTAYQMAILLMFNGADKITRFLINDTIGLDETSIRLPLLALIKTGIIECSEPSFKNWNNDTEFTVNSKFSSKKMKVSCNIAVQIGETKQSEGQQTVSEQEIEKERFFKLQAAIVRIMKSKKTMTHNDLTVETTTQVSKWFTPKITAIKKAIEYLIDQEYIRRTTDDNPSARKYEYMA
What is the function of this protein?
Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity).
What are the official names of this protein?
Cullin-5, CUL-5, Cullin-E.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: DCSA_STRLA
Sequence: MNCYPAGHLLGKGHVQLNESGENAELISQEQIGDDLNGWHRDAFEDIASRLTDPGFPCVFSRNAFRKKLVKFVFVEGSGKEDIRHLGAGLKDYVELSRDWDGALDTAYPLVVVFSADAVTADSVEQYHAFGWWVLQELHAIDPTPWPEGVDKGPQSEAWSMCFHGMPLFINMSSPAHQVRRSRNLGRHFALVINPRERFDVFAGDTPSGRKVRSNIRGRIARYDGTPHAQQLGSYGTGALEWMQYGLVEENRERADVCPFTFRGA
What is the function of this protein?
Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent.  Could catalyze the production of N(omega)-hydroxy-L-arginine (NHA) from L-arginine.
What are the official names of this protein?
Putative N(omega)-hydroxy-L-arginine synthase DcsA.
What is the protein family that this protein belongs to?
Belongs to the DcsA family.
Protein: HEMX_BREBE
Sequence: MAEVRWIYDLTIFLYAASVLFYFNDFLQSNRKVNRLAFGLLVVVWALQTAFFVSQAVMKGYFPVITLFETLFFYSWVLVGLSLAIHYFFRIDLLVFLPNIIGFVVLVMSMFLPETPIEAVSSILTSELLLTHVTLAMFSYGAFSLSMIFSAMYLLQHKMLKGRRWSPLLRRLPSLDQLEGYAYRMNMLGVPMLLLSIVLGIIWGKMVLGEKFLLDSKVLLSELVLAIYSLWLYQRYRIRCRCADSSQWNVLAFLLLLINFLGFTTSTFHDWW
What is the function of this protein?
Required for HemL synthesis.
What are the official names of this protein?
Protein HemX.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FPG_LISIN
Sequence: MPEMPEVENVRATLQELVPGKKIDQVIVRVPKMIVATPPDEFVHMLVGQEIEAVRRRGKFLLFDLTNCTILSHLRMEGKFRLMDENEEVTKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGESETKSIKKLGPEPLTPAFTLADFATGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVHPERAANSLSDKEINRIFEATKSIMTEAVALGGSTVRTYVNSQGKLGQYQDKLKVYGKTGEPCVICGTPIEKIKLNGRGTHFCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PMEA_DICD3
Sequence: MLKTISGTLALSLIIAASVHQAQAATTYNAVVSKSSSDGKTFKTIADAIASAPAGSTPFVILIKNGVYNERLTITRNNLHLKGESRNGAVIAAATAAGTLKSDGSKWGTAGSSTITISAKDFSAQSLTIRNDFDFPANQAKSDSDSSKIKDTQAVALYVTKSGDRAYFKDVSLVGYQDTLYVSGGRSFFSDCRISGTVDFIFGDGTALFNNCDLVSRYRADVKSGNVSGYLTAPSTNINQKYGLVITNSRVIRESDSVPAKSYGLGRPWHPTTTFSDGRYADPNAIGQTVFLNTSMDNHIYGWDKMSGKDKNGNTIWFNPEDSRFFEYKSYGAGATVSKDRRQLTDAQAAEYTQSKVLGDWTPTLP
What is the function of this protein?
Catalyzes the first step in maceration and soft-rotting of plant tissue.
What are the official names of this protein?
Pectinesterase A, PE A, Pectin methylesterase A, PME.
What is the protein family that this protein belongs to?
Belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted. Note=Upon overexpression also accumulates in the periplasm.
Protein: YOAC_ECO57
Sequence: MPAVIDKALDFIGAMDVSAPTPSSMNESTAKGIFKYLKELGVPASAADITARADQEGWNPGFTEKMVGWAKKMETGERSVIKNPEYFSTYMQEELKALV
What are the official names of this protein?
Uncharacterized protein YoaC.
Protein: GLGB_CHLAB
Sequence: MVERIVNSEDVSLLVSGRQSNPHKFLGIVSENSSQDRIILFRPGAHSVVVELQGNIAHAQHHHSGIFSLTAPKGTLPQDYRIYHQNGLLAHDPYAFPPLWGEVDSFLFHQGTHYKIYECMGAIPYNVQGISGVLFVVWAPHAQRVSVVGDFNFWNGLVNPLRKVSDLGVWELFIPGLEEGTLYKWEIVSASGEVLIKTDPYGKRFDVPPHAPSRVVDSDRYTWHDAAWMEKRKHRGDQPLAIYEVHVGSWQWHEGKPLGYRELAKKLAAYCKEMHYTHVELLPVTEHPLNESWGYQVTGYYAPTCRYGTPEDFQFFVDHLHRENIGVILDWVPGHFPTDGFALAHFDGEALYESIENHEPLHPHWRTYTFDYRCNEVVNFLLGSALFWLDKMHIDGLRVDAVTSMLYLDYGRQEGEWSPNIYGGRENLQAIEFIKHLNSVVHREFPGVLTFAEESTDFPKVTQAVAQGGLGFDYKWNLGWMHDTFRYIQVDPLFRSYHHKDLTFSLWYAFNERYLLPLSHDEVVHGKGSLLQKMPGDTWTKFAHMRLLLSYHICQPGKKLLFMGGEFAQGKEWTPDSPLDWHLLDHPDHAYLHKCVARMNALYCDLPYFWKGDGKQGSFRWVDFKDTENHVIAYYRFSGEDRSSALLCVHHFSSGYFPSYVLYCQDIHSCQLLFNSDDCCFGGSGKGNRQPVLCLDQHVSWGIDIELPPLATLIFHVDFVN
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: HPLN3_HUMAN
Sequence: MGLLLLVPLLLLPGSYGLPFYNGFYYSNSANDQNLGNGHGKDLLNGVKLVVETPEETLFTYQGASVILPCRYRYEPALVSPRRVRVKWWKLSENGAPEKDVLVAIGLRHRSFGDYQGRVHLRQDKEHDVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQSPNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQYPIMLPRQPCGGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAREACQEDDATIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSFGFPDPQSRLYGVYCYRQH
What is the function of this protein?
May function in hyaluronic acid binding.
What are the official names of this protein?
Hyaluronan and proteoglycan link protein 3.
What is the protein family that this protein belongs to?
Belongs to the HAPLN family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: FER3_SINFN
Sequence: MTSHFVTRDGSTWMPQYLTAIDAMTCIGCGRCFKVCSREVMHLHGIDESGEILGACDGEDDDFAGELSRTIMVVDHAGRCIGCGACARVCPKNCQTHVAADEIVA
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Putative ferredoxin-3, Ferredoxin III, FdIII.