PharMolix/UniProtQA huggingface dataset:
Protein: CSK21_YEAST
Sequence: MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIEK
What is the function of this protein?
Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).  Phosphorylates YTA7 during S-phase to promote transcription of histones (PubMed:22156209).
What are the official names of this protein?
Casein kinase II subunit alpha, CK II subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
Protein: RS8_THET2
Sequence: MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MATK_KNIUV
Sequence: MEELQRYLEKGRSRQQHFLYPLLFQEYIYALAHDHGLNSSIFYEPVEIISYDNKSSLALVKRLITRIYQQNYLISSVNDSNQNQFLGHNAFFYSHFFSQIISESFAIIVEIPFSLRLVSFFEEKEIPIYHNLRSIHSIFPFLEGKLSHLNYVSDILIPHPIHMEILVQTLQCRVQDVPFLHLLRFFLHEYHNWNSLLITQNKSIYFFSKENKRIFRLLYNSYVFECEFLLVFFRKQSYYLRLTSSGTFLERTHFYRKIEHLPIEHFFVVCRNYFHRTRWFFKNPFMHYVRYQRKAILASRGTHFLMKKWKYHFVNFWQYYFHFWSRPYRIHINHLSNYSFYFLGYLSSLLINSSAVRNQMLENSFLIDTVTNKFDTIVPVILLIRSLSKAKFCTVSGHPISKPIWADLSDSDIIDRFGRICRNLSHYHSGSSKKQDLYRIKYILRLSCARTLARKHKSTVRTFLRRLGSGLLEEFFTEEEQVLSLIFPKRTPFTLHGSHRERIWYLDIICINDLVNHSXLS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SLIRP_PONAB
Sequence: MAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEGGLRNALQQENHIIDGVKVQVHTRRPKLPQTSDDEKKDF
What is the function of this protein?
RNA-binding protein that acts as a nuclear receptor corepressor.  Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation.  Binds the STR7 loop of SRA RNA.  Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation (By similarity).
What are the official names of this protein?
SRA stem-loop-interacting RNA-binding protein, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus. Note=Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters (By similarity).
Protein: VP4_ROTHU
Sequence: MRSLIYRQLLYNSYSVDLSDEITNIGAEKKENVTVQIGEFAQSQYAPVSWGSGETLSGNVEEQPLDGPYTPDKSNLPSNYWYLINPSNDGVVFSVTDNSTLWMFTYLVLPNTAQTSVVVNVMNETVNISIDNSGSAYKFVDYFKTSSAQAYRSRNFLITAHRLQAYKRDGDGNISNYWGSDAYGDLRVGTYFNPVPNAVINLNADFYVIPDSQQEMCTEYIRRGLPAIQTTTYVTPISYAVRSQRIARPNEDITISKASLWKEVQYNRDIVIRFVFANNIIKAGGLGYKWSEISYKANNYQYTYMRDGIEVVAHTTVSVNGVSVYDYNTGSLPTDFTIRNYDVLKESSFVYVDYWDDSQAFRNMVYVRSLNAELNQVQCVGGHYSFALPVGSWPVMQGGSVVLTFDGVTLSTQFTDYVSLNSLRFRFRCAVSEPPFRVTGTRISNLYGLPAANPMGDQQYYEASGRFSLISLVPSNDDYQTPIANSVTVRQDLERQLDEMRREFNELSANIALSQLIDLALLPLDMFSMFSGIRSTIEAAKNFATSVMKKFRKSNLAKSVNSLTDAITDAAGSISRSSTLRSANSAVSVWTDISDIVDSTDNVVTATATAAAKKFRVKEFTTEFNGVSFDDISAAVVKTKMNKLNVVDEEMLPQIITEASEKFIPNRAYRLIDGDKVYEVTTEGKYFAYLTETFEEVMFDAERFAELVTYSPVISAIIDFKTIKNLNDNYGITREQALNMLRSDPKVLRSFINQNNPIIKNRIEQLILQCRI
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: FABA_MANSM
Sequence: MTDSCTLNKKSSYTYEDLLASSRGELFGPKGPQLPAPTMLMMDRVIEMNETGGNYGKGYVEAELDIKPDLFFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWIGGEGKGRALGVGEVKFTGQILPTAKKVIYRIHLKRVINRKLVMGLADGEVEVDGRVIYTATDLKVGLFQDMSTF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARL3_TAEGU
Sequence: MGLLSILRKLKSTPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRNYFENTDILIYVIDSADRKRFEETGQELAELLDEEKLSGVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALSGEGVQDGMNWVCKNVSTKKK
What is the function of this protein?
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP).  Required for normal cytokinesis and cilia signaling.  Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cell projection, cilium. Note=Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).
Protein: RPOC1_PROM4
Sequence: MTNSNLRTENHFDYVKITLASPERVMSWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDQGDHKDLKYKQLLTEDEWLEIEDEIYAEDSTIENEPVVGIGAEALQQLLEDLDLKEIAETLREEITGSKGQKRAKLIKRLRVIDNFIATNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALVDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQRADDEVMQVLQEVIDGHPILLNRAPTLHRLGIQAFEPKLVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLAIESQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTAIQPEASKPDFGDQSKTFASLDDVINAFEDKRIKLHDWVWVRFNGEVDDDDHGEPSHSETLEDGTRIEQWNLRRDRLDEQGALISRFVLTTVGRVVMNHTIIDAVAIA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: LYRA_STAS1
Sequence: MNTKRIPGFQWAMMIFIFFIVAYALPIILKDLQSSVPFKDFVFDMSTLAPFIAAFICIAIFSHRGTQLASLKLTISLKVIERAILALILPLIIFIIAMVCFNIFSDSFVLLQTKDLSVSISSIIIGQIVMAFLVELGFRSYLQHIVETKMNTFFASIIVGFMYAIWNVNIAFSFDFAIYSFLYSFAFSMIIGELIRATKGRTIYIATLFHFAMSFGLVFLFNEELGEVFAMKVIALSTAAVAILYILISLIIRTILYFFTKRNLDEVEENNYLDHVNDTDEDLTDVGDEYNVSETDETHHSANVNAATAETSSEVQDKEDPTDRHHESNASDQDNQYNSTEDTAHEDDSRANIISENTPSPSSNDSTKVDAKHSDSRANSAVEASTEKAHPESDQDEVKVNSRYTSNRQSSVVSDARTTIDEESDESSRHLSSESDDVTQQDNQPLDTADSSNADYERSPFDLKSKRGHRS
What are the official names of this protein?
Lysostaphin resistance protein A.
What is the protein family that this protein belongs to?
Belongs to the LyrA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAB_SALTY
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWRLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGTFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRVLNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKNIMELSGRTENNRVVNFEGTPEMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENELGVGFYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLAP1_MOUSE
Sequence: MGNSMKSTSPPSERPLSSSEGLESDFLAVLTDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKIGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVTHYSEVADGLCCVLTTPCLAQNIPAPTSHPSPCTSPGSPVTLRQKTFDWKRVSRLQEGSEGAENPLRVDESLFSYGLRESIASYLSLTGDDSSSFDRKKKSLSLMYTGSKRKSSFFSAPQYFED
What is the function of this protein?
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling.  Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells.  Involved in the negative regulation of positive selection and mitosis of T-cells.  May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
What are the official names of this protein?
Src-like-adapter, Src-like-adapter protein 1, SLAP-1, mSLAP.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Note=Colocalizes with endosomes.
Protein: KHSE_MYCBO
Sequence: MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEAVRWSPTVRVPG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITB_ECOLX
Sequence: MKQLEKLIIEAKILTEPEAEVERVMQVCNACRYCEGFCAVFPAMTQRLEFGKADINYLANLCHNCGACLHACQYAPPHEFAINVPKAMAEVRLETYQHYAQPAAFGALYRQAGVTVTLALVFSLILFLLLAMGLKGSLLHPPLAGDFYQIFPHNLLAWMFGSVFMLAIGLLMAGVIRFWREISPVGPRPAEIAEASHNALTLKYLDGGHGKGCNEADDAFTLMRRRFHHFTFYGFMLCFAATVVATGYHYFAGWEAPYPFFSVPVMLGTLGGIGLIVGPAGLLWLNLKRSSLHGDARQKPMDRGFILLLLLTSLTGIGLLAGRDTSWMGILLAIHLGVVMALFLTIPYGKFAHGFYRCASLLKWAIEKRRGKQAGVAGD
What are the official names of this protein?
Citrate utilization protein B.
Protein: THN6_HORVU
Sequence: MAPSKSIKSVVICVLILVLVLEQVQVEGKSCCKDTLARNCYNTCRFAGGSRPVCAGACRCKIISGPKCPSDYPKLNLLPESGEPDVTQYCTIGCTNSVCDNMDNVFRGQEMKFDMGLCSNACARFCNDGAVIQSVEA
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Leaf-specific thionin BTH6.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PIT_BUCAP
Sequence: MLYLFSYSDLNHSLFILLALFFVLCYEAINGFHDTANAVSTLIYTRATSAHFAVIMSGLFNFLGVLLGGLTVAYAIVHLLPNDLLLNSNSKNALAMVFSMLLAAILWNLSTWYFCLPASSSHSLIGAIIGIGLTNAIITDSSLLHALNVPKMTNVFLSLIFSPIVGLIISGSLIFLLRFFLKKKKNHYRIHMTPLEREQKEGKKKPPFLIKIALILSSIGVSYAHGANDGQKGIGLLMLVLIGIAPCGFLVNLNASKKEIIYTKNTIDHLYEYYSKNKVKIIKNTKNQKKIDFSIKNYNYFEIIKNIKKTKFLLQNIYDFNQLNIKQRFKLRHFLLFLSENIDQTIHFSNIVKKEKDFLKKSKKDILKTIEYAPMWIILIIALSLSVGTMIGWKRIVVTIGEKIGKKRMTYAQAMSAQITASLSIGIASYTGIPVSTTHILSSSVAGAMLSDGDGIQISTIKNIALAWILTLPVSILLSGFFYWITLLFIKNF
What is the function of this protein?
Low-affinity inorganic phosphate transporter.
What are the official names of this protein?
Low-affinity inorganic phosphate transporter.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRB_LACP3
Sequence: MTLSNFTDTSFQDFVSAEQVDDKSAMALINRAEDFKAGQTVHFPEPIYAANLFFENSTRTHTSFEMAERKLGLTVIPFDPAHSSVSKGETLEDTIKTIGAIGVNIAVMRHAQDGYYNDLLGAWPTTAIVNAGDGAGQHPSQMMLDLMTIHEEFGHFDGLSIGIVGDLSHSRVARSDMQMLHKLGATLHFAGPEQWYDSSFDQYGDFITVPELVKQVDVLMLLRVQLERFNADHRQAFSKETYHAKYGITDDLAKTMKPGAIFMHPAPVNRDVELASDLVDGPQSRIFTQMQNGVFMRMAMLEAVINARHFGEE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: E3145_ADE03
Sequence: MTDPIATSSTAAKELLDMDGRASEQRLIQLRIRQQQERAVKELRDAIGIHQCKKGIFCLVKQSKISYEITATDHRLSYELGPQRQKFTCMVGINPIVITQQSGDTKGCIQCSCDSTECIYTLLKTLCGLRDLLPMN
What is the function of this protein?
Protects virus-infected cells from TNF-induced cytolysis.
What are the official names of this protein?
Early E3 15.3 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3_15 family.
Protein: APT_CRIGR
Sequence: MAESELQLVAQRIRSFPDFPIPGVLFRDISPLLKDPASFRASIRLLASHLKSTHGGKIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTVSASYALEYGKAELEIQKDALEPGQKVVVVDDLLATGGTMCAACELLGQLQAEVVECVSLVELTSLKGREKLGSVPFFSLLQYE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB2_RHOPA
Sequence: MSLPMTETVTDPAETAPPTAERSYPRFAKPQRVAFVQSSWHRDVVAGCWESFVREIVERGIVASQVDLFEVPGSFEIPLHVQMLAKTRRYTAIVAAGLVVDDGLTGFVAQTVIQALMDVQLKTEVPVFSAVATPHSFERGSPNTEHFRQHFATKGADVAHACADTLLSLERLRGQVAAGIV
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase 2, DMRL synthase 2, LS 2, Lumazine synthase 2.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PME_BRACM
Sequence: LLVVGVAIGVVTFVNKGGGAGGDKTLNSHQKAVESLCASATDKGSCAKTLDPVKSDDPSKLIKAFMLATKDAVTKSTNFTASTEEGMGKNMNATSKAVLDYCKRVLMYALEDLETIVEEMGEDLQQSGSKMDQLKQWLTGVFNYQTDCIDDIEESELRKVMGEGIRHSKILSSNAIDIFHALTTAMSQMNVKVDDMKKGNLGETPAPDRDLLEDLDQKGLPKWHSDKDRKLMAQAGRPGAPADEGIGEGGGGGGKIKPTHVVAKDGSGQFKTISEAVKACPEKNPGRCIIYIKAGVYKEQVTIPKKVNNVFMFGDGATQTIITFDRSVGLSPGTTTSLSGTVQVESEGFMAKWIGFQNTAGPLGNQAVAFRVNGDRAVIFNCRFDGYQDTLYVNNGRQFYRNIVVSGTVDFINGKSATVIQNSLILCRKGSPGQTNHVTADGKQKGKAVKIGIVLHNCRIMADKELEADRLTVKSYLGRPWKPFATTAVIGTEIGDLIQPTGWNEWQGEKFHLTATYVEFNNRGPGANPAARVPWAKMAKSAAEVERFTVANWLTPANWIQEANVTVQLGL
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Pectinesterase/pectinesterase inhibitor.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: AP4M1_CANLF
Sequence: MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHDDRHFIHIRHSGLYLVATTSENISPFSLLELLSRLATLLGDYCGSLSEGTISRNVALVYELLDEVLDYGYVQTTSMEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSTAASRPVLASRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVLLEEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLPPKSQALNVRLHLPLPRGVVSLSQELSGPEQKAELGEGALRWDLPRVQGGSQLSGLFQMDVPGLPGPPGQGHSATAPLGLGPASLSFELPRHTCSGLQVRFLRLAFRPCGSTSPHKWVRHLSHSDAYVIRI
What is the function of this protein?
Component of the adaptor protein complex 4 (AP-4).  Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection.  They control the vesicular transport of proteins in different trafficking pathways.  AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity).  It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons (PubMed:11802162).  Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos.  The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal (By similarity).
What are the official names of this protein?
AP-4 complex subunit mu-1.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Early endosome. Note=Found in soma and dendritic shafts of neuronal cells.
Protein: RBSA_RHOBA
Sequence: MIVSDDVVFEAKQISKLFPGVKALDGVDLTLRAGRLTTLLGENGAGKSTLMKILAGVQPPDEGELLVQGEPVHFTSPRDAQDHGIAMIHQELSLVPDLTVAENIFLGREPLRFETLIDYTELNRQANEWLKRLELDVSPTTPVRRLRVGQQQLVEIARALAGNVRILIMDEPTSAITERETEVLFRCIADLKKQGVAIVYITHRLEELEQIADDIVVMRDGCLIGTAEFGELSHDAMVRMMVGRDVKILSKQSSSNNQPVLRAEGISLSHPTRPGDYLVHEVDMHVCKGEVLGIFGLMGAGRTELLECLFGLHPTASTGQVSMHDRSVRLRNPADAISHGLALVPEDRKQDGLVLSMSVGENASLASLKHAERFGFIDRGREREHTRRFVERFRVKTPSLREKIINLSGGNQQKVILAKWLATGPAVLMLDEPTRGIDIHAKNEIYSLINELTADGLAVIMVSSELPEVMAVSDRILVMCEGRATQSFDRSEATEENILQAALPRRNSIPC
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SSUB3_PSEU2
Sequence: MTSLKQQPPHLLRGIPLAVRKLKKAFGAREVLKDIDLHIPAGQFVAIVGRSGCGKSTLLRLLAGLDKPTQGQLLAGSAPLDDAREDTRLMFQEARLLPWKKIIDNVGLGLSGDWRAQALEALEAVGLAERANEWPAALSGGQKQRVALARALIHKPRLLLLDEPLGALDALTRIEMQQLIEKLWGQYGFTVLLVTHDVSEAVAIADRVILIEEGQIGLDLLVDLPRPRVRGSHRLAALEAEVLNRVLALPGSPPDPEPFSPLPTQLRWAN
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RP30_VACCC
Sequence: MENVYISSYSSNEQTSMAVAATDIRELLSQYVDDANLEDLIEWAMEKSSKYYIKNIGNTKSNIEETKFESKNNIGIEYSKDSRNKLSYRNKPSIATNLEYKTLCDMIKGTSGTEKEFLRYLLFGIKCIKKGVEYNIDKIKDVSYNDYFNVLDEKYNTPCPNCKSRNTTPMMIQTRAADEPPLVRHACRDCKQHFKPPKFRAFRNLNVTTQSIHENKEITEILPDNNPSPPESPEPASPIDDGLIRATFDRNDEPPEDDE
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG134, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 30 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 30 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.