PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_THIDA
Sequence: MATEYASSGEYIKHHLQNLTYGQHADGTWGFAHGAEEAKAMGFWAINVDSMLFSIGLGVLFLFLFRLAAKKATVGVPTGLQNFVEWVIEFIDTSVRGSFSHQNALVAPLALTVFMWVFLMNLMDLLPVDWLPYVATMAGIPYLKVVPSTDPNVTFGLSLSIFFLVLYYSVKMKGAGGFFSELAFQPFPKFLFPVNLLLEGVGLIAKPISLALRLFGNMYAGEMIFILIALMFGGGWVLALFGGALQWAWAVFHILIITLQAFIFMTLTIVYLDMAHAEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KEFC_SHIB3
Sequence: MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMD_ACHLI
Sequence: MIIDIITIFPNFFDQFLTTSKIKHAIEDKRVEINIHDLRLYTDLKGGKIDDTPYGGGAGMLMIYPPFHKLINKLKTKDTYTVLLSPQGNVFNQQVATKWRDEIKHLILICGHYEGIDDRIQNLIDEEISIGDYVLTGGEIPAMVITDSITRLIPGVINEASYMEDTHQQGLLKYPQYTKPDEYLGMSVPDILKSGHHEKIRLWRLEKSLEKTYLKRPDLLVNRDLTKEESKILSKIKKNLESQ
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANM15_ARATH
Sequence: MPLGERGGWERTESRYCGVETDFSNDVTHLLNFNISTGGFDYVLAPLVDPSYRPSLVEGNGVDTQVLPVCGSDLVLSPSQWSSHVVGKISSWIDLDSEDEVLRMDSETTLKQEIAWATHLSLQACLLPTPKGKSCANYARCVNQILQGLTTLQLWLRVPLVKSEGDSMDDTSEGLNDSWELWNSFRLLCEHDSKLSVALDVLSTLPSETSLGRWMGESVRAAILSTDAFLTNARGYPCLSKRHQKLIAGFFDHAAQVVICGKPVHNLQKPLDSSSEGTEKNPLRIYLDYVAYLFQKMESLSEQERIELGYRDFLQAPLQPLMDNLEAQTYETFERDSVKYIQYQRAVEKALVDRVPDEKASELTTVLMVVGAGRGPLVRASLQAAEETDRKLKVYAVEKNPNAVVTLHNLVKMEGWEDVVTIISCDMRFWNAPEQADILVSELLGSFGDNELSPECLDGAQRFLKPDGISIPSSYTSFIQPITASKLYNDVKAHKDLAHFETAYVVKLHSVAKLAPSQSVFTFTHPNFSTKVNNQRYKKLQFSLPSDAGSALVHGFAGYFDSVLYKDVHLGIEPTTATPNMFSWFPIFFPLRKPVEVHPDTPLEVHFWRCCGSSKVWYEWSVSSPTPSPMHNTNGRSYWVGL
What is the function of this protein?
Methylates arginine residues of myelin basic protein (MBP) in vitro.  Methylates symmetrically histone H4 of the FLC chromatin to form H4R3me2s, which in turn suppresses FLC expression to induce flowering.  Regulates alternative splicing by methylating spliceosomal proteins.  Involved in the post-transcriptional regulation of the circadian clock.
What are the official names of this protein?
Protein arginine N-methyltransferase 1.5, AtPMRT15, AtPMRT5, Shk1 kinase-binding protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDRGK_DROMO
Sequence: MDLILLVGIAIALLVILITLYFLQNKNSKTETKAAAQPQRGVPQRAQEGVPRRAQIARNQRNRLRANQNAPAAAAAAAAPAAAAIDTDNDEAAAAGDENGPRVPQGAVLDEKMGAKKRAKMEAKEQKRLQREQELHDREQRKVKEAKEDAERKQQEELEAEVERKRVEAERLAKEEREHKEHEEYLKMKAAFSIEEEGFEEGDADEKESLLADFIQYIKDNKVVLLEDLATAFKLKTQQAIERIQELQANGTITGVIDDRGKFIYVSEAELAAVAKFIKQRGRVSIADLAESSNKLINLTPVATGEGSVQ
What is the function of this protein?
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins.
What are the official names of this protein?
DDRGK domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: COAD_CAUSK
Sequence: MRIGLYPGTFDPVTNGHLDIIGRAVKLVDKLVIGVAVNIGKGPLFTLEERVATLERETAHLTKIAQIEVRPFDTLLMYFAREVGAQMIVRGLRAVADFEYEFQMTAMNQQLDREIETVFLMADPRHQAIASRLVKEIAALGGDVHKFVPPGVAEQLLAKLAK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_THETH
Sequence: MNLHEYQAKEILARYGVPVPPGKVAYTPEEAKRIAEEFGKRVVIKAQVHVGGRGKAGGVKLADTPQEAYEKAQAILGMNIKGLTVKKVLVAEAVDIAKEYYAGLILDRAKKRVVLMLSKEGGVDIEEVAAERPEAIHKFWIDPHKGFRPFEAREMVKRAGLEGNLNKLAQVLVALYRAYEGVDASIAEINPLVVTTDGGIVAADAKIVLDDNALFRHPDLAELREVEAEHPLEVEASNYGFAYVKLDGNIGIIGNGAGLVMYTLDLVNRVGGKPANFLDIGGGAKADVVYNALKVVLKDPDVKGVFINIFGGITRADEVAKGVIRALEEGLLTKPVVMRVAGTAEEEAKKLLEGKPVYMYPTSIEAAKAIVAMVGGAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity).  Can use either ATP or GTP, but prefers GTP (PubMed:22751660).
What are the official names of this protein?
Succinate--CoA ligase [GDP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: APAG_METCA
Sequence: MRRKPYELKVEVKAVYLREHSRPDAHQYTFAYTVTMENTGTVPAKLLGRRWIITDANGKTVEVVGEGVVGEHPYLRPGEAFEYTSAATIATPVGSMHGSYQLIADDGMPFEAPIAAFSLAIPRRLH
What are the official names of this protein?
Protein ApaG.
Protein: HISZ_PROMM
Sequence: MALQPAAGARDLNPQQVELNQKLSQRLAEVYRLWGYDEVSPPRVERLETLKAGGAIASQDIVRLVADEPLGLRPEMTASIARAACTRLKQRPRPLRLWAAGTIFESRTADEGSLCIEENLQSGVELFGVEPINAEMELLSLLFSAVETLELSKRHQPRLLVGHTALMDLIMLPFQNDLREKIRTALIHYDRLALESLQLPNDQFERLLHHLECRGEPLDVLERLSGLFGTQQALNNLQRLFEQMSPLAADQGIDLQLDPTFQPHFELYTGLVFQLVCQSDAAPVVIARGGRYDNLVARCGAKGLQAAGVGFSFAIDDIRELLTKEIKASDAVETTLVAYGEQATLEHALKRQRHWHKQGQRAVVELEACRDREDAFSRLSDRGCSTLDWLDH
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_RHOOB
Sequence: MPPKSRSTGPKKTQKARRRDKKNVPHGAAHIKSTFNNTIVSITDPAGNVISWASSGHVGFKGSRKSTPFAAQLAAENAARKAQEHGVKKVDVFVKGPGSGRETAIRSLQAAGLEVGTISDVTPQPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SGCD_MESAU
Sequence: MPQEQYSHHRSTMPSSEGPHIYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALYFKSARNVTVNILNDQTKVLTRLVTGPKAVEAYGKKFEVKTVSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRSLVMEAPKGVEINAEAGNMEATCRSELRLESKDGEIKLDAAKIKLPRLPRGSYTPTGTRQKVFEVCICANGRLFLSQAGTGSTCQINTSVCL
What is the function of this protein?
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
What are the official names of this protein?
Delta-sarcoglycan, Delta-SG, 35 kDa dystrophin-associated glycoprotein, 35DAG.
What is the protein family that this protein belongs to?
Belongs to the sarcoglycan beta/delta/gamma/zeta family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Single- pass type II membrane protein. Cytoplasm, cytoskeleton.
Protein: UBIA_SODGM
Sequence: MDHSLTQDRWQAWCRLMRIDKPIGSLLLLWPTLWALWLAGMAIPALGTLTVFILGVFFMRAAGCVINDYADRKIDGHVKRTRARPLPSGAIGEKEAKLLFGALVGISFALVLTLNSMTIALSTVALALAWVYPFMKRYTHLPQLVLGAAFGWSIPMVFTAVSESLPLSCWLLFLANITWTVAYDTQYAMVDRDDDLRIGVKSTAILFGRFDKLIIGLLQLATLLLLGVIGWQLGLGRIYYLALAGAAGLFLWQQKLIVDREREACFRAFLNNNLVGMLIFVGILLSLLSY
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS5_STRPD
Sequence: MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGRVGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGSGVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISVSDLA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: FTSW_IDILO
Sequence: MSTVREEQLNLEIPASDVGSRWQKLINWFQPKASQPLYDRMLFTLAMALLAFGFVMVTSASLPTADRLTGNPFHFAIRHGIYILISLAVMLATLRVPANSWNQQSGKLLLLGLIMLLMVLVVGYEVNGAQRWIKVGPITFQAAEVAKLFFCIYMASYLSRREDEVREATKGFIKPLALLFIAAVLLLMQPDFGTVVVLSATTVAMLFLAGARLWQFFAVFITCVLALILLIIVEPYRMQRLLTFLEPEKDPFGAGYQLMQSLIAFGQGHFSGAGLGNSIQKLQYLPEAHTDFIMAVVAEELGFLGVLAVIATVLMLVWRALIIGRRCLMQEQRYGGYLAYGIGIWFSIQAFVNIGVASGALPTKGLTLPLVSYGGNSLIISALAVGLLLRIDHERRMLGRKVAPRGGAE
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: PGA26_CANAL
Sequence: MHFSKIIAGSALSSVALAEFQNGTVTTHVTATGYTTYCPYPTTITLTICEEENICTKRPIVVSEPTTVTVTEPCIISTSYETTEVVVTTTLPSSLSPSSVAPANVTSFEGAGSKNVASALVGVVAIAAAMM
What is the function of this protein?
GPI-anchored protein involved in proper cell wall integrity.  Does not seem to be directly involved in the synthesis of the cell wall.  Required for normal virulence in a mouse model of disseminated candidiasis.
What are the official names of this protein?
Predicted GPI-anchored protein 26.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: ATP6_ACIB5
Sequence: MAAEEHALTSTEYIKHHLTNMTYGKMPDGTWKLAETAEEAHSMGFTAIHLDSMGWSIGLGVIFCLLFWIVARAANAGVPTKFQSAIEMIIEFVDSSVRDTFHGKSRLIAPLALTIFVWIFLMNLMDLIPVDWIPQVAAFVGANVFGMDPHHVYFKIVPSTDPNITLGMSLSVFVLILFYSIREKGVGGFVGELALNPFNPSNPVAKALLIPVNLILELVTFLARPISLALRLFGNMYAGELIFILIALLPFWIQWALSVPWAIFHILVITLQAFIFMMLTIVYLSMASEKH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THI4_METTH
Sequence: MKLDDIKISRAIVEGYMEDLLDYMEMDVAIGGGGPSGLTAGYYLARAGLKVALFERKLSIGGGMWGGGMMFNKIVVQDEGREILDEFGIRSEPYDEGYHVADSVEATSTLCSRACQAGLKIFNLMSIEDVMIRDEGITGLVLNWSSVEMAGLHVDPLTVRARAVIDATGHDCEIVKVVERKIGPELNTPDGRIQGERSMWADVGEAALIENTREVYPNLYVAGMASNAVYGAPRMGPIFGGMLVSGRRVAEMIIEKLK
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: ACPS_ORITI
Sequence: MIYGIGTDIIHIPRIEQLINKYSTKFINRILGKNEITIYQSLSIKQQTNFVAKRFAGKESVAKAIGTGITSSLLLRDIEILNNNLGKPIVYIPNAAKILLNNIKLTEYKIDISLSDDYPLAIAFTVISASI
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYAA_ZALCA
Sequence: MDIAIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQPVFRSVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVPSGVDAGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: NAGB_PROMH
Sequence: MRLIPLSTAQQVGKWSANYIVEKINAFAPSADRPFVLGLPTGGTPLATYKALIELHRAGKVSFQHVVTFNMDEYVGIPADHPQSYRTFMYENFFNHIDIKDENINLLNGNATDPQAECARYEAKIKSYGKINLFMGGVGNDGHIAFNEPASSLASRTRMKTLTEDTRLANSRFFDNDINKVPKYALTVGVGTLLDAEELMILATGINKAQAVQVATEGAVNHLWTISCVQLHPKAILVCDDPATMELRVKTLRYFQQIEAQERQQYQD
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: FDHD_VARPS
Sequence: MNLSDVPLRPGSAELLPVRGVRALQAFDNRDWVAVEVPVALEFNGIAHAVMLATPTDLADFALGFALSEGILLGRNELYGVEEAYAPEGITLKLDVASAAFARLKARRRSMAGRTGCGLCGTESLAHVTRALPPLPEGPALSTRAVARGMRELASMQVLQKVTGAVHAAAWCSAEGEALLVREDVGRHNALDKLVGALARSSVPASTGFIAVTSRASFEMVQKTVAARVPLLAAVSASTSLATAIAEDAGLTLAGFVRGDDLVIYTHPWRLNGLPANA
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP132_FOWPN
Sequence: MDQKLGNKFLEPDPKQNVFYRPLHFQYVSYENFISYRLKEILSVNRTLLSFKNDTEKIVLRINNIKIIPPDYSPIIASIKGKSYDALVTFTVDIRKEVMTKDGLHVSTISSYEGNDSQLIKIPLLIGYGNKNPLDNSKFVSPNIIGGVFINKQSIEKVGINIVEKTTTWPKFKIVKPNAYTFSFSSISPVNILPTKYRHYKITMDLSQLENCYISSAKTFITVNVIVLIKFLINQDLNYIKNNLTYGMPLETIYLINAIIESSKTILEAEDFNINDYIESLIESEFQKQRSITSIDDFRYDLMYNFLPHMVNSSDQLKGFYLLGLLRKFIYCIYHTSRYPDRDSMVCHRVLTYGRYFEILANDELENYITNIKNDITNSHKNKGVCNVSIHVLTTPGFNHAFSGLLSGKFKKTDGSYRTHPHYSWMQNISIPRSVGYYPDQVKISKMFSVRKYHPSQYAFFCPSDVPERGPQVGLISQLSVLTSVSNIRTTEYIDLKNAIMKYIYTYDKNDISYFQTGHIITIENDLVAAINPELVDKFVDDFKFRKRVNYFDNLEIGISNVKDHMNEIRINIGSGRLIRPFLVVYKGELVMDTIGEELEKRIDTITFSDIQKEYPHVIEMLDLEQFVFSNVCESVSKFRELSDEDKKLYDYCDFPNEFRDGYVASTLVGINHNSGPRAILGCAQAKQAISCLSSDLRNKIDNGIHLLYPERPIVLSKATETSKIAINCFGQHVLVALMSYKGMNQEDGIVVKREFIERGGLDIVTAKKHQVEIPIENFKNRERINSTAYSKLDINGLVRLNAFLEPGDAIAKNISSRTLDDDFVADNQISFDISEKYTDMYMSRVERVQVDLTDKVKVRVLTMKERRPIMGDKFTSRTSQKGTIAYIASESELPYDKNGVTPDIIINSTSIYSRKTISMLIEMILTSAYSVKPYNNNGKNRPICFPSSNETDIEYYIEFARKCYQSAIPDLDKDELENEVYCESILYDPETDKPYKTKVFMGPLYYLRLRHLTQDKATVRCRGKKTKLIRQANEGRKRGGGIKFGEMERDCLIAHGAANTITEILKDSEEDYQDVYVCENCGDIATKKNNNVYCIRCTKLNLYTVLTKIDTTHVSKVFLTQMNARGIKINLTFNEQNPLFYKPMKQIDLSPTILKNHDLS
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of D6 and A7, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase 132 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: ALR_ACIF5
Sequence: MTRPIVADISAAALRHNVAVVREHAPRARIMAAVKANAYGHGVTLCAPVLAEAGVDAFAVASLEEAEALHALGLERPICLLGGPFDADEVSVAAERAYLLVIHEQRQLQWLETRAADAALRLFIKVDTGMHRLGFAPERLPALFAALQRHPRWEVLGLMSHLARSDTPDDPFNRQQAGVFADAIAHVGHVTAGQHSLANSGGVLALPFTHQYWVRPGLMLYGLSPFAGRRGSEIGLQPVLSWRSAVVAIRELGPGDWLGYGAAWQAPARCRVGVVAAGYGDGYPRHLGCGAPVTVAGQTTRTLARVSMDMLFVDLTAVEADIGAPVVLMGAGGPPLESLAAELGTISYEMSCRMQMRVPRRLVS
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: GSA_METAR
Sequence: MKQDHSAQLYDEAKSLFPGGVSSPVRAIKPFPFFTKSASGSHITDVDGNEYIDCCLAYGPLILGHGHPAVKEAITKQLENGCLYGTPSEIEVKYGKLIQKYYPGMQKLRFVNTGTEATMGAIRAARGFTGRDKIVKIEGGFHGAHDAVLVKAGSGATTIGVPDSLGVPVDVVKNTLQVPYNDIHALEETLEAHKDEIACLIMEPVMGNMGPILPKDMYLRAVRNVTRDYDVLLIFDEVITGFRVSIFGAQGYYGVEPDLTTLGKIAGGGLPIGIFGGRKDIMETVAPQGGVYQAGTYNGNPLSLTAGMATVEVLEKESVHHKVNAKGKALWQSLTDIVRGLRMEGQVTPTGIASMFQLFFGPQPENYEQALKCDKLKFNEFWKHMLQNGVFFPPSQFETNFLSLAHSQADMEQIVTACKKSLAAVK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_GLUOX
Sequence: MKQQANLIRAGQVIEHDGRRWTVLKQQIITPGKGGAFIQVEMRDLKTGNKTNERWRTADSVERLVTEDKDYTYSYMDGDNVVLMDPETFEQLILAKDIFGDQFAFLQDNMPLNVKLVEGDPVGVELPPHVTLEVTEADPVVKGQTASSSYKPAMLSNGVKTLVPPFIEAGERIVVRTEDGSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_SINMW
Sequence: MQADFVIIGSGSAGSALAYRLSEDGANSVVVLEFGGSDVGPFIQMPAALAWPMSMNRYNWGYLSEPEPNLNNRRITAPRGKVIGGSSSINGMVYVRGHSEDFDRWEELGAKGWAYADVLPYYKRMEHSHGGEEGWRGTDGPLHVQRGPVKNPLFHAFIEAGKQAGFEVTEDYNGSKQEGFGLMEQTTWRGRRWSAASAYLRPALKRPNVELVRCFARKIVIENGRATGVEIERGGRTEVVRANREVIVSASSFNSPKLLMLSGIGPAAHLQEMGIDVKADRPGVGQNLQDHMEFYFQQVSTKPVSLYSWLPWFWQGVAGAQWLFFKRGLGISNQFESCAFLRSAPGVKQPDIQYHFLPVAISYDGKAAAKSHGFQVHVGYNLSKSRGDVTLRSSDPKADPVIRFNYMSHPEDWEKFRHCVRLTREIFGQKAFDLYRGPEIQPGEKVRTDEEIDAFLREHLESAYHPCGTCKMGAKDDPMAVVDPETRVIGVDGLRVADSSIFPHITYGNLNAPSIMTGEKAADHILGKQPLARSNQEPWINPRWAVSDR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: ATP6_SULDN
Sequence: MGELFTFFGLISHDKTFIYMTHMLLAAGIALMLVKMAMSNLKVVPTGTQNVMEAYISGVLKMGTDVMGQEAARRYLPLVATIGLFVGIANLIGVVPGFEAPTAFLEFAFTLALSVFIYYNYEGIRRQGVVKYFKHFLGPVWWLYWLMFPIEIVSHFSRLVSLSFRLFGNVKGDDMFLMVILMLAPWVLPMIPYALLTFMAFLQAFIFMMLTYVYLGSAIAVEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYG_STAES
Sequence: MVKNMDTIVQLAKHRGFVFPGSDIYGGLSNTWDYGPLGVELKNNIKKAWWQKFITQSPYNVGIDAAILMNPKTWEASGHLGNFNDPMIDNKDSKIRYRADKLIEDYMQNEKGDENFIADGLSFDEMKKIIDDEGIVCPVSKTANWTDIRQFNLMFKTFQGVTEDSTNELFLRPETAQGIFVNYKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFCKPGEEIEWQNYWKTFASEWLTDLNISEDNMRLRDHDEDELSHYSNATTDIEYKFPFGWGELWGIASRTDYDLRQHSEHSGEDFKYHDPETNEKYIPYCIEPSLGADRVTLAFLCDAYAEEGVEGSKDARTVMHFHPALAPYKAAVLPLSKKLSSEAIKIFEQLSSSFAIDFDESQSIGKRYRRQDEIGTPYCITFDFDSLEDNQVTVRDRDSMEQVRMPISELETFLAEKVKF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.