PharMolix/UniProtQA huggingface dataset:
Protein: PQQE_XANAC
Sequence: MSIAPPPLSVLLELTHRCPLACPYCSNPIALAALREEMDTAGWRSLLQQAADMGVLQAHFSGGEPMLRKDLPELVAHARALGLYSNLITSGVAGGEPMLDQLQAAGLEHVQLSVQDVDPAGADRIAGYRNSLSRKREFAAAVRARGLPLTINAVLHRHNAERVPGMIALALEWQAERIEVAHTQYYGWGLRNRAALMPSREQLLATIDAVETARRQLGDRLAIDFVTPDYYARQPKPCMGGWGQRFVNISPRGDVLPCHAAETIEGMRFDNLRERSLADIWNNGEAFVRFRGTAWMPEVCQGCPKREIDWGGCRCQALALSGDAATLDPVCERSPIHAQVRAAAEQESASPAPAFVYRRPERLAPAAADMLE
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: SBMC_ESCF3
Sequence: MDYEIKQEKKRTIAGFHLVGPWEKTVKQGFDQLMMWVENHNIEPLEWVAVYYDNPDEVPAEKLRCDTVVTVPENFCLPENSEGVNVTEIAGGQYAVTVARVQGHDFGTPWYQFINSLLEDSQYQMAHKPCFEVYLNNGAVDGYWDIEMYVPVLPK
What is the function of this protein?
Inhibits the supercoiling activity of DNA gyrase.  Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase.  It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
What are the official names of this protein?
DNA gyrase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_COLP3
Sequence: MRSLYCGEVNESHIGQEITLCGWVNKRRDLGAVIFLDLRDREGLVQVVYDPDLPEVIKKANTLRNEFCVQIKGKVRARPEGQVNKGMKTGGIEVLGLELTILNKSAPLPLDSNQVNSEELRLKYRYLDLRRVEMTERLRFRAKVTSAVRSSLESQGFLDIETPILTAATPEGARDYLVPSRTHKGQFFALPQSPQLFKQLLMMSGMERYYQIVKCFRDEDLRADRQPEFTQIDIETSFMSSDQVMEVTEKMIRELFQELLDVDLGEFPRMPYSEAMTRFGSDKPDLRNPLELIDVDDILKDVEFKVFSGPANDENGRVAVICLPQGAAKFSRKGLDELTKFVGIYGAKGMPWLKVNDIDAALSTGVEGLQSPILKFLSSDEAIALLKRTNAKTGDIIFFGADQYNVVTESLGALRLKLGEELDLLQGEWKPLWVVDFPMFEEVDGHMHAIHHPFTAPTNLTAEQLEANPVGALSDAYDMVLNGCELGGGSVRIHNQDMQAAVFRILGISDEEAEEKFGFLLEALQYGAPPHAGLAFGLDRLVMLMTGASSIRDVMAFPKTNTAACPLTNAPGKANPEQLRELGVAVLEVKKAEENKDEEQA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_RUEPO
Sequence: MLKTRIIPCLDVADGRVVKGVNFVGLRDAGDPVDAARAYDAAGADEICFLDIHATHENRGTMFDVVSRTAEQCFVPLTVGGGVRTHADVRALLLAGADKVSFNSAAVANPDVIAEAADRFGSQCIVCAIDAKTVEPGRWEIFTHGGRKPTGIDAVEFARLVTAKGAGEILLTSMDRDGTKSGFNLPLTRAIADAVDVPVIASGGVGTLDHLVEGVTEGHASAVLAASIFHFGEYTIREAKEHMAAAGIPMRLT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: META1_ILYPC
Sequence: MPIVIPKKLPAFDTLKGENIFVMNKSRAFSQDIRPLKIVILNLMPNKIVTETQLLRLLGNTPLQIEITLLKTRTYASKNTSQDHLTSFYKTFEDIKNHTFDGLIITGAPIEHLQFEDVDYWEELKEVMEFSKSNVTSTMHICWGSQAGLYYHYGIPKFPTDKKIFGIFKHKIFNLKTKITRGFDDEFLVPHSRHTTVMRGDIENVPELEILAESEDAGICLVATRDRKHIFISGHLEYEKDTLKSEYFRDLDKGRSIDIPKNYFKDDNPENDPVVTWRAHAHLLFSNWLNYCVYQETPYILK
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase 1, HAT 1, Homoserine transacetylase 1, HTA 1.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO2_MOUSE
Sequence: MAPLLALFYLLQLGPGLAALFCNQNVNITGGNFTLSHGWAPGSLLIYSCPLGRYPSPAWRKCQSNGQWLTPRSSSHHTLRSSRMVKAVCKPVRCLAPSSFENGIYFPRLVSYPVGSNVSFECEQDFTLRGSPVRYCRPNGLWDGETAVCDNGASHCPNPGISVGTARTGLNFDLGDKVRYRCSSSNMVLTGSAERECQSNGVWSGSEPICRQPYSYDFPEDVASALDTSLTNLLGATNPTQNLLTKSLGRKIIIQRSGHLNLYLLLDASQSVTEKDFDIFKKSAELMVERIFSFEVNVSVAIITFASQPKTIMSILSERSQDVTEVITSLDSASYKDHENATGTNTYEVLIRVYSMMQSQMDRLGMETSAWKEIRHTIILLTDGKSNMGDSPKKAVTRIRELLSIEQNRDDYLDIYAIGVGKLDVDWKELNELGSKKDGERHAFILQDAKALQQIFEHMLDVSKLTDTICGVGNMSANASDQERTPWQVTFKPKSKETCQGSLISDQWVLTAAHCFHDIQMEDHHLWRVNVGDPTSQHGKEFLVEDVIIAPGFNVHAKRKQGISEFYADDIALLKLSRKVKMSTHARPICLPCTVGANMALRRSPGSTCKDHETELLSQQKVPAHFVALNGNRLNINLRTGPEWTRCIQAVSQNKNIFPSLTNVSEVVTDQFLCSGMEEEDDNPCKGESGGAVFLGRRYRFFQVGLVSWGLFDPCHGSSNKNLRKKPPRGVLPRDFHISLFRLQPWLRQHLDGVLDFLPL
What is the function of this protein?
Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a.  C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
What are the official names of this protein?
Complement C2, C3/C5 convertase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LKHA4_VANPO
Sequence: MLSQFTRSLSCFVKPTPPKLNKLTRTMTVLPKILQDARPKVSPELDYSTYSNYQNFKINHTDLNLNISFDDSIVNGFVTFNLNKIDKSCNEIRLDTSFLTVDSVEIDDAKVDFQLKDRLEPLGSQLIINPPTATSLNNEFNLKLGFSTTKDCTALQWLNGEQTSSGKPYVFSQLEAIHARALFPCFDTPSVKSTFNAAITSTLPVVFSGIEQSVVDNGNGTKTYNFKQSVPIPAYLIGIASGDLVSGEIGPRSKVYTEPFRLKDCEWEFSGDVEKFIQAAEKIIFPYEWGTYDILVNVNSYPYGGMESPNMTFATPTLIAYDKSNIDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIVAAIHGEATRHFSALIGWNDLANSISAMKNPDRFSTLIQNLNDGTDPDEAFSSVPYEKGFNLLFHLETILGGPKEFDPFIKHYFTKFSKKSLDSYQFFDTLFEFFADKREILDAVDWETWLYKPGMPPKPKFITTLADNVYSLAEKWATEIKNGNTTEDDLKQAFTAADIKDFNSNQIVLFLDTLVQNKEIQWNNHHTAAKTLLKIYEDSIVKSRNAEVVFRTYRFEITAQLKESYPQLAEWLATVGRMKFVRPGYRLLNSVDRPLALATFEKLQNIYHPICKALVKQDLEA
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SRB3_CAEEL
Sequence: MLETNDSVCELAYQLAYHPVYRSSQFWSMLVSSLSIPALIYFITRKIFFLHFHGNLKCLLIVYFICNLLFSMALCFAFFYQFLIPFFVTSKCQLLINTTLFKWGQICSFLLLTSSMLLPIGFSIERFVALGNAQKYESSRTFLGPVIIFIIIAVDFSIIFSVYKNEPFTEGFYSFILVPSTTASQINMYFFVLLFVKIFNLLLNCILLRIHKKIRIKYYSLSVRYEMEEILQSSKFTFIIRFTHLLFFGFYVVVILFVRIMGESFFNGTLNYSVARGVFCTVPTYNLIIVIIGIKSLRHLNLQRLNKVQSTVQIKSTGKEGSKNYEDIITNYWDSVSSRTP
What is the function of this protein?
G-protein coupled receptor.
What are the official names of this protein?
Serpentine receptor class beta-3, Protein srb-3.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite.
Protein: CTL2_DANRE
Sequence: MDMEEKPKYGEPRKFDPSFKGPIQNRGCTDIVCCIIFIIAILGYLAVGILAWTHGDPRKVIYPTDSMGQFCGQGKLEKQPFLFYFNMMKCASPMVLLEFQCPTPQVCVQTCPNRTMTLITAISKPQDWEYYKSYCKEDPGHKAAAQILKEKLCPAYLVSSNPFLQRCFPSMGKKGEVITVGDQEKFSDGVNVLDAKDLMAGMKNASIVMEGRQVAMKIFEDYTKSWYWILICLLIAVVLSLIFIVLLRFLAGVMVWVMILMVVAVIAYGIAHCSIKYVSLKDTPGSNITLQQLGFQPDFAVYLHIRQTWLAFIIILAILELIIILLLIFLRNRIRVAVELMKEASRAIGYVMSSLVFPIFTFFLLAIVIAFWGVNAVFLSTSSEPVYKVFNETECVHSRETCNPENFTSSSMKSDCPHSQCLFAFYGGETPYHKYLILLQFYNVFLFFWCANFVTALGQMTLAGAFASYYWAFDKSKDMPAFPLCASLGRSLRYHTGSLAFGSLLLAIVQVIRVLLEYIDHKLKGAENKFAKFLLCCLKCCFWCLEKFIKFINRNAYIMVAIYGKNFCRSARDAFFLLMRNVVRVVVLDKVTDFILFLGKLLIVGLVGIFAFFFFSGQTDAFKGTAPSLHYYWVPILTVLVCSYLIAHGFFSVYAMCVDTLFLCFLEDLERNDGSAERPYLMSENLLNVLKKKNQAN
What is the function of this protein?
Choline transporter.
What are the official names of this protein?
Choline transporter-like protein 2, Solute carrier family 44 member 2.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: METE_ECO45
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPQRHQNNDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHKVKPVLLGPITYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLNAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: IF4A2_RAT
Sequence: MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-II, eIF-4A-II, eIF4A-II, ATP-dependent RNA helicase eIF4A-2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: MINC_SHELP
Sequence: MQKPSLELKGSSFTLSVLHINDADLDGVARELDDKLAIAPQFFLGAPLVVNLSAISDPDYNLAGLKDLLISRQLVIVGITGAPSAIANQAKALGLALIKSGKQSQTQPQLPKTTKIVKQNIRSGQQIYAQNGDLIIIGAVGNGAEVIADGSIHIYGSLRGKAMAGANGDKNAVIIAQNIDAELVSIAGQYWLTENLQAHASIKSGCIRLDGDSLTVEALSL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: NAB_DROME
Sequence: MEASSNPTTPTTAVATTTSTSSPSPAASTSSKGHSQSATASASASATQSQLLTTSLEMPKTEDLYNLSVASGLSEGQRSLSGAPSASSSPIMSPQGKIFGRNANGTMITTSRPGNEAEVQLYRVLQRASLLAYYDTLLEMGGDDVQQLYDAGEEEFLEIMALVGMASKPLHVRRLQKALHEWANNPGLFQGPMMPHLGLCETPPKPALIFNPDTTPALPRQKFPSFNPSGSSFMPSPVPPAPLPASASVPAPTVPLATQISCPSAPSVPLPLVLPPNPLTSSPHPSANSNLPANTAHQVSSSSPQLTPVLTEAQIQRITMCADKIGRQLPQREPRAQTTRKRTTRELEQVIAMGEQDPRRMDEIRKYSAIYGRFDCKRRPEKPLTLHEVCVNEAAAQLCRNPQTIWLLTRRDELFPLARQIVKDAGFGHSASIARYGGLLTQLPSQGAGLGGGRAPGDTDCESSDAAVPSKRQRLSSTEAAQLPLDLNREAVEDSRYNLFAMYQKFAKPPFDLSEIAKFSVSKAADYEDNDSRFSFSNSSSPTMPTPCNGMEGERSPVSRQMETSSPPRESVDLSGTSSGAALSGVQVISAAGDNIIAVANPALALSPALNEVLALKRSAASPET
What is the function of this protein?
Transcriptional regulator that can both act as a coactivator or a corepressor depending on the context.  Lacks DNA-binding domains and acts by associating with other transcription factors such as rotund (rn) and squeeze (sqz).  Acts as a coactivator of sqz and is required to limit the number of neurons that express the LIM-homeodomain gene apterous and to specify Tv neuronal fate.  Acts as corepressor of rn in wing development and is required to limit the expression of wingless (wg) in the wing hinge, where wg plays a mitogenic role.
What are the official names of this protein?
NGFI-A-binding protein homolog, dNAB.
What is the protein family that this protein belongs to?
Belongs to the NAB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL35_MICAN
Sequence: MPKLKTRKAAAKRFEATGSGKKIKRRKAFKNHLLDHKSAERKRRRLSQITLVHERDEKEVRLMLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MIAB_GRAFK
Sequence: MEKIIDEKKQGNSLVLEPKAKNTRKLFIESYGCAMNFSDSEIVASILSKEGFNTTQNLEEADLVLVNTCSIREKAEQTVRKRLEKYNAVKRINPGMKVGVLGCMAERLKDKFLEEEKIVDLVVGPDAYKDLPNLINEVEEGRDAINVILSKEETYGDISPVRLQSNGVSAFVSITRGCDNMCTFCVVPFTRGRERSRDPQSIVEEVNDLAAKGYKEITLLGQNVDSYLWYGGGLKKDFKNATEIQKATATNFAALLKLVAEAQPKMRIRFSTSNPQDMTLDVIEAMAAYRNICNYIHLPVQSGSDRILKKMNRLHTREEYFTLIDNIKKMIPNCGISHDLITGFPTETEEDHQDTLSLMEYVKYDFGYMFTYSERPGTTAERKLEDDIPEETKKRRLQEIVDLQQKHSKQNTNSVIGTTVEVLIEKESKKSNKHWSGRNERNTVTVFSKENYQIGDFVKVKIHDCTSATLIGEPIGLSDNN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R9BP_CHICK
Sequence: MVKEECKALLDALSRVTACYRHMVLTIGGTSDSQNLREELKKTRQKAQELAVANRNKLTTVLRDKTVSKEDKAEFERLWVIFSTCLEILEIDMRRALELGHEFPLNVPKKHLIQTGMSGGTSGVAARAMSVQNMKYEAEHNIDVVDLKDLENEINQVGEMMYEMEMKVNVPQWTVEAKQDPGAELKSTISVGASSIGMISVEENKSFCDISKVLAGIIFSAVLIIAIVLAVCVVKLS
What is the function of this protein?
Regulator of G protein-coupled receptor (GPCR) signaling.  Probably acts by regulating the activity of some 'R7' family protein (RGS6, RGS7, RGS9 and/or RGS11).
What are the official names of this protein?
Regulator of G-protein signaling 9-binding protein, RGS9-anchor protein.
What is the protein family that this protein belongs to?
Belongs to the RGS7BP/RGS9BP family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: VPS28_MOUSE
Sequence: MFHGIPATPGVGAPGNKPELYEEVKLYKNAREREKYDNMAELFAVVKTMQALEKAYIKDCVTPNEYTAACSRLLVQYKAAFRQVQGSEISSIDEFCRKFRLDCPLAMERIKEDRPITIKDDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVRQMLFDLESAYNAFNRFLHA
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 28 homolog, Caspase-activated DNase inhibitor that interacts with ASK1, CIIA, ESCRT-I complex subunit VPS28.
What is the protein family that this protein belongs to?
Belongs to the VPS28 family.
What are the subcellular locations of this protein?
Cell membrane. Late endosome membrane; Peripheral membrane protein.
Protein: UBE2F_XENLA
Sequence: MLTLASKLKRDDGVKGSRTTSTTLDSMRRISVRDRLLVKEVAELEANLPCTCKVNFPDPNKLHYFHLTVSPDESYYQGGRFQFEIEVPDAYNMVPPKVKCLTRIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKDEYRNKVEDYIKRYAR
What is the function of this protein?
Accepts the ubiquitin-like protein NEDD8 from the uba3-nae1 E1 complex and catalyzes its covalent attachment to other proteins.  The specific interaction with the E3 ubiquitin ligase rbx2, but not rbx1, suggests that the rbx2-ube2f complex neddylates specific target proteins, such as cul5.
What are the official names of this protein?
NEDD8-conjugating enzyme UBE2F, NEDD8 carrier protein UBE2F, NEDD8-conjugating enzyme 2, Ubiquitin-conjugating enzyme E2 F.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Protein: TRMA_SACD2
Sequence: MTTKLGQANPANYQQQLDDKEKATKEQFSDFWQGDIEVHPSPPSHYRMRAEFKMWQQGAEAFYAMYQPGEYKKPVTLEWEFSVGAEKIVELMPKLLEIVNASELLRKRLFQVEFLTTTTGESVTTLIYHKPLTEEWQAEANALASSLNTHIIGRSKKQKIVLTQDYVEETLTISGTPFTYKQIESGFTQPNAAVCQKMLQWAVDATANLGGDLVELYCGNGNFTLPLSKNFDKVLATEVSKTSVKAAEYNIEKNGCKNITIARMSSEEFTEALNGVREFRRLKDIELDSYNFSTVFVDPPRAGLDEDTEALISRFDNIIYISCNPDTLANNLANLCKTHKVERFALFDQFPYTDHRECGVILTKK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: GATP2_ORYSJ
Sequence: MNLIKHAAFAASFQGETDCTSHASARKFSTSGSSPLLDSTEGNGFKGHSMLAPFTAGWHSTDLEPLIIERSEGSYVYDSKGNKYLDTLAGLWCTALGGSEPRLVKAATDQLNKLPFYHSFWNSTAKPPLDLAEELISMFTAKEMGKVFFTNSGSEANDSQVKLVWYYNNALGRPNKKKIIAQSQAYHGSTLISASLSGLPAMHLKFDLPAPFVLHTDCPHYWRFGLPGEAEEEFATRLADNLENLILKEGPETVAAFIAEPVIGAGGVIPPPKTYFEKIQAVLQKYDVLFIADEVITGFGRLGTMFGSDLYNIKPDLVSLAKALSSAYVPIGATLVSPEISDVVHSQSNKIGFFAHGFTYSGHPVSCAVALEALKIYRERNIPAHVKQISPRFQEGIKAFAGSSIIGETRGVGLLLATEFANNKSPNDPFPVEWGVAQIFGAECKKRGMLVKVVGDEIAMSPPLIMSQREVDGLVSIYGEALKATEERVAELRSKKK
What is the function of this protein?
Transaminase that degrades gamma-amino butyric acid (GABA).
What are the official names of this protein?
Probable gamma-aminobutyrate transaminase 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y1593_NEIMA
Sequence: MRLTTKGRFAVTAMLDLAMNAQTGAVKLSAISERQNISLSYLEQLFGKLRRAGLVESLRGPGGGYILAAPAARINIAQIIAAAEDRLDATQCGSKANCHHGAPCLTHDLWENLNKTINDYLGSVTLQSIIEQKNNGDGSRVVQFTHIH
What are the official names of this protein?
Putative HTH-type transcriptional regulator NMA1593.
Protein: HEM2_ECOLI
Sequence: MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: MURA_BORA1
Sequence: MDKLRITGGARLHGEVVISGAKNSALPILCASLLTADPVRLSNVPQLNDTRTMLRLLGQMGVKAESAQTSVNLQADQVHSLEAPYELVKTMRASILVLGPLLARFGEARVSLPGGCTIGQRPVDQHIKGLEALGAQITMEHGFVVARAKRLKGASVRTDMVTVTGTENLLMAATLAEGQTILENAAREPEVIDLAELLIKMGARIQGHGTDRIVIDGVERLHGADHTVISDRIEAGTFLCAVGATGGDITLRNTDAAIMGATLDKLTEAGLHIESGPGWIRGVMNGRPKPVGIRTHEYPGFATDMQAQLMALNTIADGTAIVVENIFENRFMHVQELCRLGADIDIDGHTAVVRGVARLSGATVMATDLRASASLVIAGLAAEGDTLIDRIYHLDRGYDRMEIKLRNLGARIERVTGKEDE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXK4_ORYSJ
Sequence: MSAAAAIASPIPAAIAVVQQQRRGRSRGGGSGAAAVRCSAVAPTSAIAPILADLRLRCAAPLPVLRRVADAMASGMRAGLADDGAGELKMIPSHVYSLPTGNETGLFYALDLGGTNFRVLRVQLGGKDKRIIDTEFEQVSIPREIMHGITEDLFDFIASGLSRFVATEGDKFHLPQGRKRELGFTFSFPVNQTSIDSGILIKWTKGFAVSGTAGKDVVACLNAAMERQGLDMRVSALVNDTVGTLAGARYWDDDVMVAVILGTGTNACYIQRTEAIPKLQHLKLETGNTIINTEWGAFSDGLPLTEFDREMDDESINPGEQIFEKTISGMYLGEIVRRVLVKMAEVSDLFGHSFPKKLAEPFVLRTPHLCAMQQDTSDNLGEVESILSDVIGVSQASLLARRVTVEVSDCIIRRGGRLAGAGIVGILEKMENDSRGHIFGRRTVVAMDGGLYEKYPQYRRYMKEAVAELLGPERSNRIAIEHTKDGSGIGAALLAAANSKYAAAQISTR
What is the function of this protein?
Fructose and glucose phosphorylating enzyme.
What are the official names of this protein?
Hexokinase-4, chloroplastic, Hexokinase II.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: YOL66_YEAST
Sequence: MHVLYSTSAHILPSGRHINVARTPWLRLDIVSIIGILLHSGPIAGFSINMIIFRDAFIPLTKVIENKKMNNIISYSYIYIYIYICHITVENPGDITDKHYTRMNVSHYYIIT
What are the official names of this protein?
Putative uncharacterized protein YOL166C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL29_BRUAB
Sequence: MKAADVRAKSLDQLNDELGTLKKEQFNLRFQKATGQLEKTARVKQVRRDIARIKTIARQKAAESKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ACS3_RUTGR
Sequence: MESLKEMRKAQMSEGPAAILAIGTANPDNVYMQADYPDYYFKMTKSEHMTELKDKFRTLCEKSMIRKRHMCFSEEFLKANPEVCKHMGKSLNARQDIAVVETPRLGNEAAVKAIKEWGQPKSSITHLIFCSSAGVDMPGADYQLTRILGLNPSVKRMMIYQQGCYAGGTVLRLAKDLAENNKGSRVLVVCSELTAPTFRGPSPDAVDSLVGQALFADGAAALVVGADPDSSIERALYYLVSASQMLLPDSDGAIEGHIREEGLTVHLKKDVPALFSGNIDTPLVEAFKPLGISDWNSIFWIAHPGGPAILDQIEEKLGLKEDKLRASKHVMSEYGNMSSSCVLFVLDEMRSRSLQDGKSTTGEGLDWGVLFGFGPGLTVETIVLRSVPIEA
What are the official names of this protein?
Probable acridone synthase 3, Acridone synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.