PharMolix/UniProtQA huggingface dataset:
Protein: NU1M_WICCA
Sequence: MIILNIVEMIVLFIFILLSVAYLTVAERKTLGYMQRRVGPNIVGYYGQLMAIADALKLLLKEIIIVRESDKILIIISPIIALCFALLSWAVIPFSPGIAIGDMNYSLLYILVIGSIGVFGTLLVGWSSNSKFTLLASIRSTAQLISYELILTTNIIICILLNNTLNLNSFIDNQQTIWLILPLLPIGIIHYIARIAETSRPPFDNVEAESELVSGHMTELSASPFVLFYLQEYNNIVIMCFLNIILFFGGYLFWLPFIDNGSNLINFIINYFNINNFNFIYIIEIIFYVINISFKSIILTYGFIWVRASFPRLRYDLLVNLCWVIFLPLLFSLLILIPHILYIFDSFNIYN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPOA_SYNWW
Sequence: MLEMEKPRIDCVEKNSSSNYGRFVIEPLERGYGTTLGNSLRRVLLSSLPGAAVTSIKIDGVLHEFSTIPGVLEDTTEIILNIKKLVLSYTGSERKIIRLEQQGPKEVKASDITPDAEVEILNPDLHLASLDEDGKVEIEMTVERGRGYVSSDQQPQKNDDIVGLIPIDSIFTPVSRVNYTVENARVGKRTDYDRLNLEVWTNGSISPEEAISLSAQILIEYLKLFTEIDDTYAEVEILVEKEEEKKDKILEMSIEELELSVRASNGLKRASINTVGDLIAKNREEMSKIRNLGQKSLEEIERKLKELNLSFRKSED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PRUN2_RAT
Sequence: MDIHFEEGVLSPSATDMRPEPPNSLDLNGSHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYPGHEDPMANRSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIIKYDEEKSFKRSVRTSCLYNDPEMTSMEKDIDMKLKEKP
What is the function of this protein?
May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.
What are the official names of this protein?
Protein prune homolog 2, BNIP2 motif-containing molecule at the C-terminal region 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INGR1_HUMAN
Sequence: MALLFLLPLVMQGVSRAEMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVEVKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEKQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGSLWIPVVAALLLFLVLSLVFICFYIKKINPLKEKSIILPKSLISVVRSATLETKPESKYVSLITSYQPFSLEKEVVCEEPLSPATVPGMHTEDNPGKVEHTEELSSITEVVTTEENIPDVVPGSHLTPIERESSSPLSSNQSEPGSIALNSYHSRNCSESDHSRNGFDTDSSCLESHSSLSDSEFPPNNKGEIKTEGQELITVIKAPTSFGYDKPHVLVDLLVDDSGKESLIGYRPTEDSKEFS
What is the function of this protein?
Receptor subunit for interferon gamma/INFG that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation (PubMed:20015550).  Associates with transmembrane accessory factor IFNGR2 to form a functional receptor (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460, PubMed:7673114).  Upon ligand binding, the intracellular domain of IFNGR1 opens out to allow association of downstream signaling components JAK1 and JAK2.  In turn, activated JAK1 phosphorylates IFNGR1 to form a docking site for STAT1.  Subsequent phosphorylation of STAT1 leads to dimerization, translocation to the nucleus, and stimulation of target gene transcription (PubMed:28883123).  STAT3 can also be activated in a similar manner although activation seems weaker.  IFNGR1 intracellular domain phosphorylation also provides a docking site for SOCS1 that regulates the JAK-STAT pathway by competing with STAT1 binding to IFNGR1 (By similarity).
What are the official names of this protein?
Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, Interferon gamma receptor alpha-chain, IFN-gamma-R-alpha.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
Protein: TRMD_SULNB
Sequence: MHFSFVTLFPNIIEGYFSDSILKRAIDDGKISIDFYNPRDLTTDKHNRVDAPMIGGGAGMLMTPQPLMDTLSKIKEESPEAHIVFLSPVAKPFIQNDAKRLVKKEHIVFVSGRYEGIDERVIERHADELFSIGDFILTGGELASMVLCDAVARNVEGVLGNSVSLEVESFEASLLEAPSFTKPINYENNEVVSEFLKGNHSKITDLKRGLALCKTKFFRPDLYKKKV
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_MAIZE
Sequence: MTRTNDASGGGKLPRKRFYRARAHSNPLSDSHFPVPISPEEVDLSQHYPRYFPADKGSDGEEAAAPQQIRFADVGCGFGGLLVGLSPLFPDTLMIGMELRDKVTEYVKERILALRGANPGQYDNISVVRTNSMKYIPNYFRKAQLTKMFFLFPDPHFKEKNHRRRVISMQLLDEYAYVMEVGGIIYTITDVEELGEWMRSCLEKHPLFETVPEEEIKADPVFKLLSTATEESQKVARNGGQTFYAIFRRISLQEE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HRTA_STAES
Sequence: MGLVVKDISKTFGEKSSKTEVLKDINFEVKDGEFIILNGASGSGKTTLLTILGGLLSQTSGDVVYEGKSLFERHTNKAHLRLNDIGFIFQASHLVPYLKVLDQLTLIGKEAGMSSKEAQARAKELLTKIGLEEQLNSYPHMLSGGQQQRVAIMRALMNHPKIVLADEPTASLDASRAQEVVEMIRKQIKANQMIGIMITHDESLFKYADRIVQLYDGKIKNS
What is the function of this protein?
Part of the ABC transporter complex hrt involved in hemin import.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative hemin import ATP-binding protein HrtA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. HrtA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS16_THEP3
Sequence: MAVRIRLKRFGAKKRPFYRIVVADSRSPRDGRFIDEIGYYNPIAQPAEIKIDVEKAKKWLSVGAQPSDTVKSLFKKEGIIGNSASQ
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RUVA_VIBPA
Sequence: MIGRLRGILLEKQPPEVLIEVNGIGYEVQMPMSCFYELPNIGEEAIIYTHFVVREDAQLLYGFNTVKERALFREVIKANGVGPKLGLGILSGMTASQFVSCVEREDVSTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPFTDAAPTDSAAASSNSAEEEAVSALLALGYKPTQASKVVSQIAKPDMSSEQLIREALKSMV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ZIPA_PSEFS
Sequence: MEIGLREWLIVIGIIVIAGILFDGWRRMRGGKGKLKFRLDRNLSNLPDDDGSAELLGPPRVLDTHKEPQLDEHDLPSMSAPVREAREPSSKRGKRANAGVAEPHQGDLNLDVDEGPSFSSRDDDFPDENAGKNAPRQSVNDQPPAEEVLVISVICRDAAGFKGPALLQNILESGLRFGEMDIFHRHESMAGNGEVLFSMANAVKPGTFDLDDIDLFSTPAVSFFLGLPGPRHPKQAFDVMVAAARKLSQELNGELKDDQRSVLTAQTIEHYRQRIVEFERRALTQKR
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: REPB_BACSP
Sequence: MKHGIQSQKVVAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQGFRRMMQYKKINKNLVGFMRATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKVQMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYGGLLKEIHKKLNLDDTEEGDLIHTDDDEKADEDGFSIIAMWNWERKNYFIKE
What is the function of this protein?
Produces a single-strand nick in a specific site of the plasmid, and this nick results in single-strand replication by rolling circle mechanism.
What are the official names of this protein?
Replication protein.
What is the protein family that this protein belongs to?
Belongs to the Gram-positive plasmids replication protein type 1 family.
Protein: ALR_RICCK
Sequence: MSLCTLAINLSAIKNNYFLLQDICKTSLVGAVVKADGYGLGAVQISKALIEENCRHFFVASSEEGVNVRKALGIDVNILVLNGVFEHDALELIEYNLIPILNNLKQIEIWQQFGNLKNLLLPCYLHFNTGINRLGLSSNEIEQLINNRDLLKGLNLQYIISHLAISEEIDNPYNLEQLNKFKAYLRYFPSIKASLANSGGIFLGQDYHFDLVRPGAALYGLNPLMQNPVTLKAPIIHLQNLTLDSHIGYNMTFTTKRDSVIATLPLGYADGYSRNFSNQGKVFINGRSVPIVGRVSMDLINIDVTDLPPSDIFLGQEVEIIGNHCTPDKIASIIGTIGYEVLTSLGNRYRRKYTR
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: HEM3_CHLPD
Sequence: MKKQLIIGTRSSPLALWQAEFTKAELSRHYPELDITLKLVKTTGDVLLDSPLSKIGDMGLFTKDIEKHLIAKEIDLAVHSLKDVPTSTPEGLIITSFTEREDTRDVIISRSGETLLNLPQNARIATSSLRRMSQLLSMRPDFEICDIRGNLNTRFKKFDEGEFDAMMLAYAGVFRLKFSDRISEILPHDVMLPAVGQGALGIETRVDDEQTREIVRILNHSNTEYCCRAERALLRHLQGGCQIPIGAYASFKNGTLKLLAFVGSVNGKIGLRNEITKTGLVSPEQAEEAGIELAKELLKQGADEILSEIRKTR
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: SISA_DROME
Sequence: MERSHLYLPTLSYAAMGHVYAPYRGSSSPALSTASSTSSKPEQIEELVSQQLHHLKMHYADEEQRYVDQMLLENPIVVERRAPPPLKTELAMDCRGSGSGSGSGSGSDVKDAQRQRAESCRKSRYNNKIKKAKLRFRHKFVSGQLKKSAVMLDTMRDVIAQAERQLLERGYPAATLERMRATFGLEMEQ
What is the function of this protein?
Involved in sex determination and dosage compensation.  Required for proper expression of Sxl in embryonic somatic cells.  Also has an essential function in the yolk nuclei.  Involved in endoderm migration and midgut formation.
What are the official names of this protein?
Protein sisterless A.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSUD_XANAC
Sequence: MDMFWFIPTHGDSRYLGTSDGARQVSAEYVTQVAVAADTLGYEGVLIPTGRSCEDPWVIASSLINATRRLKFLVALRPGLMAPALAARTAASFDRLSGGRLLVNLVTGGDRGELEGDGVFLDHAERYEASAEFIRIWREIIAHSHSGESYDFDGKHLQVKAAKLLYPTVQRPYPPVWFGGSSDAAHDLAAEQVDTYLTWGEPPDAVAEKIASVRSKAAALGRTLTFGIRLHVIVRETEAEAWAAAESLISHLDDETVERAQSAFARMDSVGQRRMAALHSRGQRRTRADLEVSPNLWAGVGLVRGGAGTALVGDPQTVAKRIEEYAALGIDTFIFSGYPHLEEAYRFAELVFPLLPRTVKQKLPGQALSGPFGEVIANTIVPRASAR
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: CYOE_SERP5
Sequence: MIKQYLQVTKPGIIFGNLISVVGGFLLASKGSIDYPLFLATLVGVSLVVASGCVFNNYIDRDIDKKMERTKNRVLVKGLIAPSVSLVYATALGIAGFALLYIGANPLAMWLAVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTNEFDAGALILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITVYIVAFMIATLMLTLGGYAGYKYLIVAAAVSVWWLGMALRGYKTENDSVWARKLFVFSIVAITSLSVMMSIDFSATAAPEALMTYVW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUTC_ECOKI
Sequence: MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: DABA2_HALNC
Sequence: MTTLTSLQRSEAQRNHIVDLIDKACLRIAPIWPLDSFVAVNPYLGLIDQPFDTVGRYLEQTVGESLFMDHGWFADKIAQGEITDDDLAQAAQQLDPSISLDTIKQQLAVHRQPAPALPLVTNELDRRDAPPVSEFVIEQVSQFMANYYDRGQALWHLPKEASASLFAQWRRYTLINRSASAVGLKQVRQHLLAVPSDAIDALFWALDQINLPESRLPDYLFTLLKTIGGWASWCRYLHFQAGLHGESQHDLRDLLIIRLVWVALVIKETSSAGRQQWRAKLNDWFDPAKLVASPSATATASTKAQSSRIDEILLAAAEQAFRRRINAGLNRQPADAPDQQAERPTVQAAFCIDVRSEVFRRHLEASSPGLETIGFAGFFGLPIDYCRMGESEARLQNPVLINPAYRAQETGDPAIAQHRHARQSRGAIWKQFKLSAASCFTFVESAGLSYVPRLLADSLGWHRSSLPPDAPGLTPEERARLHPQLVKLDGGALSTQEKVDLAEKVLRGLGLTHTFAPIVLLAGHGSSTTNNPHRAGLDCGACAGQAGDVNARVAVQLLNEAAVRLGLIERGIAIPRDTRFVAALHDTTTDHIELLDLDQSGIESDQLSSLTQALKQAGELTRLERLVTLEAQVDTVDAEKQATFRGRDWSQVRPEWGLAGNAAFIAAPRWRTRGLDLGGRAFLHDYDWRHDKEFGVLNVIMTAPLIVANWINLQYYGSTVDNLHQGAGNKVLHNVVGGTVGVIEGNGGDLRVGLAMQSLHDGEQWRHEPLRLSAYIEAPIAEIDKIIAGHDMLNALINNRWMHILHIDDNGIPHRRHAHGDWRPEPI
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump; its substrate may be carbon dioxide.  Expression of both dabA2 and dabB2 (DAB2) restores growth in ambient air to E. coli deleted of its carbonic anhydrase genes (called CAfree, deletion of 'can' and 'cynT'); neither dabA2 or dabB2 alone is sufficient.  Rescue is pH-independent, suggesting it transports CO(2) and not carbonate ions.  Together the genes allow greater than normal uptake of inorganic carbon by E. coli (PubMed:31406332).  Uptake of carbon dioxide rather than bicarbonate has been suggested based on kinetic calculations (Probable).
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA2.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNZ2_MACFA
Sequence: MWALCSLLRSATGRTMSQGRTISQGSARRQRPPKDPLRHLRTREKRGPSGSSGGANTVYLQVVAVGSRDAGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYKDETMTVYQIPIHSEQRSGKHQPWQSPERPLGRLSPERSSDSESNESEPHLPRGVSQRRGVRDPSLVVAFICKLHLKRGSFLVLKAKELGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPPDPGAAFVVVECPDEGFIQPICENATFQRYQGKADAPVALVVHMAPESVLADSRYQQWMERFGPDTQHLVLNENCASVHNLRSYKIQTQLNLIHPDIFPLLTSFPRKKEGPTLSVPVVQGECLLKYQLRPRREWQRDAIITCNPEEFIDEALQLPNFQESMQEYRRSAQDGPAPAEKRSQYPEIVFLGTGSAVPMKTRNVSATLVNISPDTSLLLDCGEGTFGQLYRHYGDQVDRVLGSLAAVFVSHLHADHHTGLLNILLQRERALASLGKPFHPLLVVAPTQLKAWLQQYHNQCQEVLHHVSMIPAKYLQVGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCRHAFGCALVHTSGWKVVYSGDTMPCEALVQMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAIRVGMRMNAEFIMLNHFSQRYAKVPLFSPDFNEKVGIAFDHMKVSFGDFPTVPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRALTDDLEDGEPQQKRAHTEEPQSKKVRAQ
What is the function of this protein?
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity.  Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.  Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
What are the official names of this protein?
Zinc phosphodiesterase ELAC protein 2, ElaC homolog protein 2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z 2.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Nucleus. Note=Mainly mitochondrial.
Protein: QUEF_RHIME
Sequence: MTKTDVSGLSQLGAKVDLPQSPEEAVLERVPSGHGGTDFVVRFTAPEFTSLCPMTGQPDFAHIVIDYVPDGWLVESKSLKLFLHSFRNHGAFHEDCTIEIAKRLVSLLSPKWLRIGAYWYPRGGIPIDVFWQTGNPPEGVWLPDQGVPTYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_METBF
Sequence: MSFKNRNVISMKDFSRKEINYILDTAEKLEPVARGKKRSRLLDGKIIALLFFEPSTRTRLSFESAAQRLGGQVLNLGSVEASSVMKGENLADTIRVISKYADLIVLRHPLDGSARMAAEFASVPIINGGDGSLHHPTQTFLDLYTIRRESHLEGLKIAMAGDLKYGRTVHSLCHALSLYGAEITLVSPPELRMPQEIIRDLQKNNIRIRETDALEEIIGDVEVLYMTRVQRERFPDPEEYEKVKNKLKVTGDLLKNADPSLKILHPLPRVNEISPEVDSTPYACYFEQAFYGVPTRMALLALATGVIE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TPIS_CULPI
Sequence: SITELCKVLTTGPLNADTEVVVGCPAPYLSLARSQLPDTVGVAAQNCYKVAKGAFTGEISPAMLKDLNIGWVILGHSERRAIFGESGELIADKIVHALAEGLKVIACIGETLQEREAAKTEAVCFRQTKAIADKVKDWSNVVIAYEPVWAIGTGKTATPEQAQEVHAALRKWFTENVSADVSSAIRIQYGGSVTAANCRELAAKPD
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: APAH_SALPA
Sequence: MATYLIGDVHGCYDELIALLQQVEFMPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGIYALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: LODB_MARM1
Sequence: MESYDAIVIGGGPAGAASALSLLTHHNKRVLLLERGDFSQARIGEQVSHSIFDFLAYLDLPVSEFGESCFSPNYGKTSLWGSSIESHHLSMFATQGATYQLDRAAFDETLLMAFVERGGTVIPRCKQMKIEQSDSVWQVQFVHPEQGEQTVCCDYLVDASGRQSKLSAMLGVEPVMDDQLVGVGAFIRNPDNAFEQHQRIESCEYGWWYMAGLSSELAVVTCFTDMDIMREMRLNKASVWNQYLAETSAIADCVKGSETTHPKLWVKQAHSQYCTSELPDRFIAVGDAALSFDPVSSMGIGFAMTSACHSTRALVSDSKDAVLQYQQDMARIYQEYHVTKTRIYQREKRWPNQLFWQRRHAFSALQHAS
What is the function of this protein?
Is required for lysine-epsilon oxidase (LOD) activity in M. mediterranea.  May be involved in the generation of the quinonic cofactor of LodA, leading to the active form of LodA containing a tyrosine-derived quinone cofactor.
What are the official names of this protein?
Putative FAD-dependent oxidoreductase LodB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1252_COLP3
Sequence: MSSLENQLLIAMPSLGDPYFNKTVTYICEHNEDGAMGLIINLPVNITLADLLKQIEPDEGDKTGNVNSNSELTKSDDVNDITLVTDITNSLEQLVLAGGPIAQQRGFVLHSSQPGWSSSLVLSKELMITTSKDILMALGTQQAPEQFIVTLGYAGWGPGQLEQELQANSWLTTPADIEILFKTPIEQRWKKATEKLGIDLAHLSTDIGHA
What are the official names of this protein?
UPF0301 protein CPS_1252.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: SURE_THEMA
Sequence: MRILVTNDDGIQSKGIIVLAELLSEEHEVFVVAPDKERSATGHSITIHVPLWMKKVFISERVVAYSTTGTPADCVKLAYNVVMDKRVDLIVSGVNRGPNMGMDILHSGTVSGAMEGAMMNIPSIAISSANYESPDFEGAARFLIDFLKEFDFSLLDPFTMLNINVPAGEIKGWRFTRQSRRRWNDYFEERVSPFGEKYYWMMGEVIEDDDRDDVDYKAVREGYVSITPIHPFLTNEQCLKKLREVYD
What is the function of this protein?
Nucleotidase that preferentially dephosphorylates 5'-GMP and 5'-AMP.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C_PHAVU
Sequence: MEYTHQYSWIIPFIPFPVPMLIGVGLLLFPTATKKIRRIWAFPSILLLTIVMFFSLDLSIHQIQNSSIFQYVWSWTINNDISLEFGYLIDSLTSIMSILITTVGILVLIYSDNYMSHDQGYLRFFAYMTLFNISMLGLVTSSNLIQIYFFWELIGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGIYWITGSLEFRDLFQIINNLISKNEMNLFFVTLFALLLFCGSVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFVLLPQIMNTIAFIGLITVILGATLAIAQKDIKKNLAYSTMSQLGYMMLALGMGSYRGALFHLITHAYSKALLFLGSGSIIHSMEALVGYSPAKSQNMVFMGGLTKHVPITKFFFLVGTLSLCGIPPFACFWSKDEILNDSRLYSPIVAIIACSAAALTAFYMFRIYLLVFEGYLNVHFLNFNGKKNSSFYSISLWGKKQVKLKIKNENFLLVLLKIKKNEITSFFIRKRYLHRVNQNIKNISRLFFGIMDFGMKKTACLYPNESNNTMQFSMLVLVLFTLFVGAIGISFSQGIDLDILSKLLIPFIDLLHKDSKNFVNYYEFFTNATFSLILTFWGIFIASFFYKSVYSYLKNLNLLNLFEKNFIKKKFSDHFQNIIYNWSYNHGYIDVFYEISFISSIRRLVKFNSFFDKKRIDGITNGIGITSFFLGEAIKNVGGGRISSYILLYILDILIFILIYINFVFIRY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KBL_MOUSE
Sequence: MWASFMWHGALSPGRRAHSALAQLRCILDSELEGIRGAGTWKSERVITSRQGPSIRVDGISGGILNFCANNYLGLSSHPAVIQAGLQTLEEFGAGLSSTRFICGTQSIHKNLEAKIAHFHQREDAILYPSCFDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAKLKEAQKHRLRLVATDGAFSMDGDIAPLQDICRLAAQYGALVFVDECHATGFLGPTGRGTDELLGVMDQVTIINSTLGKALGGASGGYTTGPEPLVSLLRQRSRPYLFSNSLPPAVVGCASKALDLLMESNAIIQSMAAKTRRFRSKMEAAGFTVSGADHPICPVMLGDARLSSQMADDMLKKGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEVGRLHGALP
What is the function of this protein?
Pyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and acetyl-CoA.  Catalyzes the second reaction step on the main metabolic degradation pathway for L-threonine.
What are the official names of this protein?
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, AKB ligase, Aminoacetone synthase, Glycine acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus. Note=Translocates to the nucleus upon cold and osmotic stress.