PharMolix/UniProtQA huggingface dataset:
Protein: ILI6_ORYSJ
Sequence: MSSRRSRSRQSGSSRITDEQISDLVSKLQDLLPEARLRSNDRVPSSRVLQETCNYIRSLHQEVDDLSERLSELLATSDMSSAQAAIIRSLLM
What is the function of this protein?
Atypical and probable non DNA-binding bHLH transcription factor that acts as a positive regulator of grain size.  Binds the transcription repressor APG and forms a heterodimer of antagonistic bHLH transcription factors that regulates grain length and weight by controlling cell elongation in lemma and palea.  May be involved in the control of lamina inclination through brassinosteroid signaling pathway.
What are the official names of this protein?
Transcription factor ILI6, OsILI6, Protein INCREASED LEAF INCLINATION 6, Protein POSITIVE REGULATOR OF GRAIN LENGTH 1.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NOSZ_BRUSU
Sequence: MTEETRKSQLSRRQLLGTSAFVAAAGASGLGGALLAGSSETALAAGAAKGGMSPEVKPGELDEYYVFFSSGQCGEVRIVGLPSMRELMRIPVFNRDSATGWGLTNESRKVLTEGLLPQDREFLKDRGDIFLNGDLHHPHPSFTDGTYDGRYLYANDKANTRVCRIRLDVMKCDKIIQLPNQHTVHGLRVQKYPKTGYVFCNGEDRVPIPNDGSHLNDVKQYHAIFTAVDGETMKVAWQVMVDGNLDNVDCDYQGKYAFSTCYNSEEGTTLAEMMSSEQDWIVVFNLKRIEEAVANGDFKEMNGVPVIDGRHGSKYTRYIPVPNSPHGINTAPDGIHVVANGKLSPTVTVFDVRKFDDLFDDKIKPRDAVVAEPELGLGPLHTAYDDKGNAYTTLFIDSQICKWNIEDAKRAFKGEKVDPIRQKLDVHYQPGHNHSSMGQTKEVDGKWLISLNKFSKDRYLNVGPLKPENDQLIDISGDKMVIVHDGPSFAEPHDATIVHRSKINPVSFWSREDPFFADAVAQAKADGLDLMEANEVVRDGNKVRVYMTSSAPAFGLTEFTVQQDDEVTVYVTNIDEIEDLTHGFAIVNYGVNMEVAPQATASVTFKASKPGVWWYYCSWFCHAMHMEMQGRMLVEPKKA
What is the function of this protein?
Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
What are the official names of this protein?
Nitrous-oxide reductase, N(2)OR, N2O reductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATPE_BURP6
Sequence: MATIKVDVVSAEEQIFSGQAKFVALPGEAGELGILPGHTPLITRIRPGAVRIESESGDEEFVFVAGGILEVQPGAVTVLADTAIRGKDLDAAKAEEARKRAEETLQNAKSDIDLAKAQSELATAMAQLEAIQRLAKIRGKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SECE_RICRH
Sequence: MFKEYKIYKFFEQVKQETYKVVWPTRKELVASTLVVVVAVFIFSLICLVLDYSIHNIMQLLLNIGK
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CHNA_RHOS6
Sequence: MTDNLPLRGKVALVTGAARGIGRAYALRLAKRGADVAVVDFDLHSYKDYQLEAASMRGDTVVDEIREIGMRALGFQADVTDATTLNEAVQQIVGEWGRLDIAICNAGGGVGSPEETRASIVEKDLVDVVVARNLTGTIHTCQAVAVPMKEQRSGKIVTVGSQAGHRIEDNGGYAHYGAAKAAVAKYTQYLARDLGPFGVTVNCVAPGYISTGRLAPILSAMGDAQLLDDVPLGRYGTPEDCAGVIEFLSSDLSDYVTGAIIPVDGGLTYS
What is the function of this protein?
Catalyzes the oxidation of cyclohexanol to cyclohexanone.  Can also use a broad range of other alcohols, including trans-cyclohexane-1,2-diol, trans-cyclopentane-1,2-diol, cyclopentanol, hexane-1,2-diol, ethanol, 1-propanol, 1-butanol, 1-pentanol and 1-hexanol.
What are the official names of this protein?
Cyclohexanol dehydrogenase, Cyclohexanol dehydrogenase II, CHD II.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_ECO55
Sequence: MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVIAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PLD2_BOVIN
Sequence: MAATPQSLFPSGDDLDSSQLQMEPDEVDTLKEGEDPADRMHPFLAIYHLQPLKLHPLVFAPGVPVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLLRHKVFMSLLPLARFAVASSPAPEGDSREIPSLPRAGPEGSSRRTASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGCKGLEGVIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFKVQVGKRSTEARYGVRVDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFIQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEIYLKRPAHSDDWRLDIMLKKKAEEGVHVSVLLFKEVELALAINSGYSKKALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSESAAPQPPTSCSDLPATPDLTHNQLFWLGKDYSNLITKDWVQLDRPFDDFIDRETMPRMPWRDIGVVVHGSPARDLARHFIQRWNFTKTTKTKYKIPIYPYLLPKSTSTANQLPFTLSGGQCATVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTEWRNYISVCGLRTHGELGGHPVSELIYIHSKMLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTEMEPSLMNGVEYQAGRFALSLRKHCFSVILGAAARPHLDLRDPVCDAFFQLWQDTAESNANIYEQIFRCLPSNATRSLRALREYVVVEPLATVSPPLARSELNQVQGHLVHFPLKFLEDEYLLPSLGSKEGVMPLEVWT
What is the function of this protein?
Function as phospholipase selective for phosphatidylcholine.  May have a role in signal-induced cytoskeletal regulation and/or endocytosis.
What are the official names of this protein?
Phospholipase D2, PLD 2, Choline phosphatase 2, Phosphatidylcholine-hydrolyzing phospholipase D2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CC033_MOUSE
Sequence: MARPPASLGSQAPDRDRGEANVVTRVSQWADNHLRLVQNISTGMAIAGIMLLIRSVRLTSKFTTSSDIPVEFIRKKVKLRGRLQRITECGLEIEHIPITLPFISSWKEEPRGVLLVKLAGVELTESGKVWLQAELKPSQLLWFQLLGKEDSALFCYLLVNKGGYFNVNLNEEILRRGLGKTVLVKGLNYDSKTHWKIHRNLLKAELTALKKGEGIWKEESEKESYFRKLKDSWRERWTKDNDLKPAGADLGSTKDSYHDSRRRASGKGKDSVSNYSFFLKLREFVSRLHFWRKG
What is the function of this protein?
May play a role in transcription regulation.
What are the official names of this protein?
Protein C3orf33 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HCP_ENT38
Sequence: MFCVQCEQTIRTPAGNGCSYSQGMCGKTAETSDLQDLLIAALQGLSAWAAKAREYGIVDHYVDNFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQSLNADANAAVDNPMADLQLVSDDLGDLQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPSDMNALLECSMEIGQMNFKVMSILDAGETDTYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLQQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGSYDDRIWTRSIVGWPGVSHLEGDDFAPVITQAQQMAGFPFSEIEHMITVGFGRETLLGAADSLIDLVSREKLRHIFLVGGCDGARGERNYFTDFATSVPQDCLILTLACGKYRFNKLDFGDIEGLPRLIDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVTNIVTGPTAPGFLTPDLLAVLNEKFGLRSVTTVEEDMQQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAA28_MYCMM
Sequence: MSVRSLPAALRACARLQPNDPAFTFMNYEQNWDGAAETLTWSQLYRRTLNVARELSSCGSVGDRAVILAPQGLEYVVAFLGALQAGRIAVPLSVPQGGASDERATSVLRDASPVAILTTSPVIDDVTQHVSAQSAGPAPSIIELDRLDLDAAAGSGAGTENYPATAYLQYTSGSTREPAGVMLSHQNLVTNFEQLMSGYFADTDGIAPPDSTLVSWLPFYHDMGLVLGVCAPILGGYQAVLTSPVSFLQRPARWLQMLATSSHAFSAAPNFAFELAAKKVSDDDMAGLDLGNVLTILSGSERVQPATLKRFADRFARFNLQEKVLRPSYGLAEATVYVSTSRPGQPPELVEFDAESLSTGQAKQCESGAGTQLVSYVLPRSPIVRVVDPDTCTECPDGTVGEIWVCGDNVAIGYWNKPEESERTFGGKLASPSEGTPEGPWLRTGDSGFITDGKMFIIGRIKDLLIVYGRNHSPDDIEATIQEITRSRCAAISVPGDRSTEKLVAIIEYRRRGDSDQEAMDMLVAVKREVTSALSNSHGLSVADLVLVAPGSIPTTTSGKVRRAACVEQYRQQQFARLDV
What is the function of this protein?
Involved in the biosynthesis of phthiocerol dimycocerosate (PDIM), a cell wall-associated lipid found only in pathogenic mycobacteria.  Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the multifunctional polyketide synthase Mas for further chain extension.
What are the official names of this protein?
Long-chain-fatty-acid--AMP ligase FadD28, Acyl-AMP synthetase, Long-chain fatty acid adenylyltransferase FadD28.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: YBEY_CYTH3
Sequence: MKEETIFFFKEDTQYQLRQRAEIRTWLNTIAKKEKYSILELNYIFCSDEYLLQMNRDFLDHDYYTDIITFDNSEVKGKIEGDIFISIDRVKDNAQLQHSTVKDELHRVLAHGLLHLTGYKDKTTKEKEMMRAKEDASLSLRKF
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUG_SALHS
Sequence: MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLAGFTDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIEKIEDYQPAALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELDQALIMRGL
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_DESVM
Sequence: MRLHELYPFAEERASRKRVGRGSGSGLGCTSGKGNKGQNARAGGGVRPGFEGGQMPLQRRLPKRGFKNAPFKATYEVINLDRLVASFEGKTDITLEDIYARGLCKAGASVKILGVGEVSVALTVEAHKFSASAAEKIRNAGGEAKALEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PEPT_ECOHS
Sequence: MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVDRADMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAQRK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_FERNB
Sequence: MELKNFIRDIPDFPQKGVMFRDITPLVKNPEAFKYAIDTIAEELGKYDFDLIVCPEARGFIIAAPLAYKLDKGLVPVRKPGKLPYKTISDVYELEYGKAELHMHEDAIQPNQKVVIIDDVLATGGTAMALKRLVEKAGGIVVASAFLIELTYLNPRNIIKDLPIIAPIKY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPPE_ARATH
Sequence: MVRFIEENITKMLETKAISNSEVLYVGGDDGDTSPTTKVLHDFQINSGGGLIRSWVDSMRACSPTRPKSFNSQSCWIKEHPSALNMFEEILHKSEGKQIVMFLDYDGTLSPIVDDPDRAFMSKKMRNTVRKLAKCFPTAIVSGRCREKVSSFVKLTELYYAGSHGMDIKGPEQGSKYKKENQSLLCQPATEFLPVINEVYKKLVENTQSIPGAKVENNKFCASVHFRCVEENKWSDLAHQVRSVLKNYPKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYDNCTDVFPIYIGDDRTDEDAFKILRDKKQGLGILVSKYAKETNASYSLQEPDEVMVFLERLVEWKQSRCGA
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.  Trehalose accumulation in plant may improve abiotic stress tolerance (By similarity).
What are the official names of this protein?
Probable trehalose-phosphate phosphatase E, AtTPPE, Trehalose 6-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: NRDR_ERWT9
Sequence: MHCPFCCAVDTKVIDSRLVGEGSSVRRRRQCVVCHERFTTFEVAELVMPRVVKSNDVREPFNEDKLRSGLMKALEKRPVSSDAVENAISHIKSKLRATGEREVASKSIGSLVMDELKKLDKVAYIRFASVYRSFEDIREFGEEIARLQD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NUOA_POLAQ
Sequence: MNLANYFPVLLFILVGIGVGLVPMFLGKILAPSKPDAEKLSPYECGFEAFEDARMKFDVRYYLIAILFILFDLETAFLFPWGVALRDIGWFGYASMVIFLLEFIVGFVYIWKKGALDWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDRP_STAAC
Sequence: MEKIKIIVASDSIGETAELVARAGISQFNPKQCKNELLRYPYIESFEDVDEVIQVAKDTNAIIVYTLIKPEMKQYMSEKVAEFQLKSVDIMGPLMDLLSASVEEKPYNEPGIVHRLDDAYFKKIDAIEFAVKYDDGKDPKGLPKADIVLLGISRTSKTPLSQYLAHKSYKVMNVPIVPEVTPPDGLYDINPKKCIALKISEEKLNRIRKERLKQLGLGDTARYATEARIQEELNYFEEIVSEIGCPVIDVSQKAIEETANDIIHYIEQNKSK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: COF_SHIFL
Sequence: MARLVAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKESPALLQVFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVRTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: FIS_ALIFM
Sequence: MFDQSMTSEALTVTTVTAQDQITQKPLRDSVKASLKNYLGQLNGQEVNDLYELVLAEVEQPLLDMIMQHTRGNQTKAANMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: MURB_CLOAB
Sequence: MDYFQDFIAALSNFIKKDNLKIDVPMKNHTSFKVGGPVDVLVMPEKYEEINRIIELCEKYDVNYYIIGNGSNLLVRDGGLRGVAIKLLKLNKLQIGNNKIIAGCGVPLGYLSRKARDKSLTGLEFACGIPGSVGGAVAMNAGAYNGEISNVVESVLVIDNKGKMKRLYRDELQFGYRSSAILKHKYIALEVTFTLQKGDREKIANRIDDLMRRRIEKQPLEYPSAGSTFKRPVGHFAAKLIEDSGLKGKGIGGAQVSDKHSGFIINKNDATAKDILDLIKFVQNTVKSKFNVELDTEVRIIGEDK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_YERPP
Sequence: MAIVLGIDPGSRVTGYGVIRQQGRQLTYLGSGCIRTVVDDMPTRLKLIYAGVTEIITQFQPDFFAIEQVFMAKNPDSALKLGQARGAAIVAAVNLNLPVSEYAARQVKQTVVGTGAAEKSQVQHMVRSLLKLPANPQADAADALAIAITHCHLSQNTLRLGNDQMTLSRGRIR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RIP_LUFAC
Sequence: DVSFSLSGSSSTSYSKFIGALRKALPSNGTVYNITLLLSSASGASRYTLMKLSNYDGKAITVAIDVTNVYIMGYLVNSTSYFFNESDAKLASQYVFAGSTIVTLPYSGNYEKLQTAAGKIREKIPLGFPALDSAITTLFHYDSTAAAAAFLVIIQTTAESSRFKYIEGQIIMRISKNGVPSLATISLENEWSALSKQIQLAQTNNGTFKTPVVIMDAGGQRVEIGNVGSKVVTKNIQLLLN
What are the official names of this protein?
Ribosome-inactivating protein luffaculin 1, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: RL6_RHOBA
Sequence: MSRIGNKPVAIPSGVTVSIADRNIDVEGPKGKLSFKHRPEVKVAVDSDTNQVIVSRDGDDRPSREFHGLTRAIVANMLVGVKDGYEKKLEIVGVGYLASISGDTLQLRVGYANELHRKIPTDLTVTCPDQTHVVIQGCDKQSVGQFAAEIRSLRKPEPYKGKGIRYQGEQVKIKPGKSATK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CYB_EPICE
Sequence: MPHQQLLMLFGLLPVATNISTWWNFGSMLLACSALQVLTGFFLAVHYTANINLAFSSIIHITRDVPYGWLMQNIHAIGASMFFICIYIHIARGLYYGSYLNKETWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTMTTCLWGGFAINDPTLTRFFALHFILPFGIISLSSLHVLLLHEVGSSNPLGTNSDIEKIPFHPYHTYKDFFMLAAMITTLMLIVSFFPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALALSIAILLTVPFTHTSNLRSMMFRPLMQLMFWTFAATFLVITWTATKPVEPPFTTISQVAASMYFLFFISNPIMGWMENKITXT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GAR5A_MOUSE
Sequence: MKGGRDLKAARGGADRPLAPAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDESRQQLKVKFRTGRAFYLQLRSPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTAPEEEEEEEEEEEEEEVKEGQLQPPEFQATEARLDPQVSELWGL
What is the function of this protein?
RAB2B effector protein which promotes cytosolic DNA-induced innate immune responses.  Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis.
What are the official names of this protein?
Golgi-associated RAB2 interactor protein 5A, Golgi-associated RAB2B interactor-like 5, GARIL5.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: SECA1_NITMU
Sequence: MLNNLLKKVFGSRNDRLIKQYSQNVTAINALEAKIGALSDAELRGKTEEFRQRIGEGADLDMLLPEAFAVVREAGKRVLGMRHFDVQLIGGMVLHDGKIAEMRTGEGKTLMATLPAYLNALAGKGVHLVTVNDYLAKRDAEWMGRIYRFLGISVGVILSQMDHGDKQAAYAADITYGTNNEYGFDYLRDNMVTHPLERVQRVLNFAIVDEVDSILIDEARTPLIISGQAEGNTDVYVRMNALIPKLVRQENEDSPGDFSVDEKAQQVLLSEAGFEHAEKLLVQSGLLPSGTSLYDPANINLVHHLYAGLRAHALFHRDQHYVIQNGEVVIVDEFTGRLMAGRRWSEGLHQAVEAKEGVTIQKENQTLASITFQNYFRMYEKLAGMTGTADTEAYEFQQIYGLETVIIPTHRPMIRVDRMDQVFRTMDEKYQAIIADIKDCQERGQPVLVGTTSIENNELLSSLLTREKLPHQVLNAKQHAREAEIVAQAGRPKMITIATNMAGRGTDIVLGGNPEPEFERIRSDESLSESEKTERIAELQQQWQTLHDEVLEKGGLHIIGTERHESRRVDNQLRGRSGRQGDPGSSRFYLSLEDALLRIFASDRVASIMQRLNMPQGEAIEHPWVTRAIENAQRKVEARNFDIRKQLLEYDDVANDQRKVIYQQRNELLESEDITETTTAMRADMLRNLIALHVPPQSVEEEWDISGLEKALAAEYHLTLPLREWLEKEPDLHEDSLHQRIIEAANALYSGKVEQVGAPIMHQYERAVMLQSLDMHWREHLASLDHLRQGIHLRGYAQKNPKQEYKREAFELFTSMLEEIKAEVSKTLMAVQIRSEQQVEAVAETHHAPVNVQYHHAAFEEALGEEKSPESIGEDIEGREHPQKHQPFVRQGEKIGRNDPCPCGSGKKYKQCHGKLN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GREA_BRUME
Sequence: MEKFPMTPRGFEKLKEELRWRQQSERPRIIEAIAEARAHGDLSENAEYHAAKEAQSLNEGRINELEDLVARAEVIDVSKLTGDRIKFGATVTMIDEDTEEEKIYQIVGDQEADVKEGRISISSPIARALIGKGEGDTIEVNAPGGSRSYEIIALKFV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.