PharMolix/UniProtQA huggingface dataset:
Protein: RSMH_SHEB2
Sequence: MSQEFAHLSVLLAETVGGLNIKDDGIYIDGTFGRGGHSRQVLQQLGENGRLIAIDRDPQAIEAAKQFADDPRFQIVHGGFGQLADYVEELGLVGKIDGVLLDLGVSSPQLDDAERGFSFMRDGPLDMRMDNSQGQTAAQWLARAEIEDMAWVFKTYGEEKNARHIARCIAADRDKTPFLRTKDLADLIARITKSKERNKHPATRVFQAIRIYINSELDQIDQALEGAVNVLAPQGRLSVISFHSLEDRIVKRFIRRHSQGESVPHGFPVTEDQINKSRKLRAVGKAIMPSDEEIERNARARSSVLRIAERLDY
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIP2_MORS1
Sequence: MPILPVPALNALLTKTIKTIKTGAAKNAHQHHVLHHTLKGLDNLPAPVLERINRRLKASTAEQYPLADAHLRLILAISNKLKRPLAIDKLPKLRQKFGTDAVSLQAPSVWQQNADASGSTENAVSWQDKTIANADGGDMTVRCYQKSTQNSERKSTDEAAMLFFHGGGFCIGDIDTHHEFCHTVCAQTGWAVVSVDYRMAPEYPAPTALKDCLAAYAWLAEHSQSLGASPSRIVLSGDSAGGCLAALVAQQVIKPIDALWQDNNQAPAADKKVNDTFKNSLADLPRPLAQLPLYPVTDYEAEYPSWELYGEGLLLDHNDAEVFNSAYTQHSGLPQSHPLISVMHGDNTQLCPSYIVVAELDILRDEGLAYAELLQKEGVQVQTYTVLGAPHGFINLMSVHQGLGNQTTYIINEFACLVQNLLTSEGDKPNLRA
What are the official names of this protein?
Lipase 2, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: AB1A_ARATH
Sequence: MGSSKRQFKAMLRKNWLLKTRHPFVTSAEILLPTIVMLLLIAVRTRVDTTIHPAHSNIDKDTVVEVGKGNSPSFPEVLKLLLAEGDFLAFAPDTDETNNMIDILSLKFPELRLVTKIFKDDIELETYITSAHYGVCSEVRNCSNPKIKGAVVFHEQGPHLFDYSIRLNHTWAFAGFPNVKSIMDTNGPYINDLEMGINTIPTMQYSFSGFLTLQQVVDSFIIFASQQNNDLPLSHSNLSSALRFELPWTLFSPSVIRMVPFPTREYTDDEFQSIVKSVMGLLYLLGFLFPISRLISYSVFEKEQKIREGLYMMGLKDEIFHLSWFITYALQFALCSGIITACTMGSLFKYSDKTLVFTYFFLFGLSAIMLSFMISTFFTRAKTAVAVGTLTFLGAFFPYYTVNDESVSMVLKVVASLLSPTAFALGSINFADYERAHVGLRWSNIWRASSGVSFFVCLLMMLLDSILYCALGLYLDKVLPRENGVRYPWNFIFSKYFGRKKNNLQNRIPGFETDMFPADIEVNQGEPFDPVFESISLEMRQQELDGRCIQVRNLHKVYASRRGNCCAVNSLQLTLYENQILSLLGHNGAGKSTTISMLVGLLPPTSGDALILGNSIITNMDEIRKELGVCPQHDILFPELTVREHLEMFAVLKGVEEGSLKSTVVDMAEEVGLSDKINTLVRALSGGMKRKLSLGIALIGNSKVIILDEPTSGMDPYSMRLTWQLIKKIKKGRIILLTTHSMDEAEELGDRIGIMANGSLKCCGSSIFLKHHYGVGYTLTLVKTSPTVSVAAHIVHRHIPSATCVSEVGNEISFKLPLASLPCFENMFREIESCMKNSVDRSKISEIEDSDYPGIQSYGISVTTLEEVFLRVAGCNLDIEDKQEDIFVSPDTKSSLVCIGSNQKSSMQPKLLASCNDGAGVIITSVAKAFRLIVAAVWTLIGFISIQCCGCSIISRSMFWRHCKALFIKRARSACRDRKTVAFQFIIPAVFLLFGLLFLQLKPHPDQKSITLTTAYFNPLLSGKGGGGPIPFDLSVPIAKEVAQYIEGGWIQPLRNTSYKFPNPKEALADAIDAAGPTLGPTLLSMSEFLMSSFDQSYQSRYGSILMDGQHPDGSLGYTVLHNGTCQHAGPIYINVMHAAILRLATGNKNMTIQTRNHPLPPTKTQRIQRHDLDAFSAAIIVNIAFSFIPASFAVPIVKEREVKAKHQQLISGVSVLSYWLSTYVWDFISFLFPSTFAIILFYAFGLEQFIGIGRFLPTVLMLLEYGLAIASSTYCLTFFFTEHSMAQNVILMVHFFSGLILMVISFVMGLIPATASANSYLKNFFRLSPGFCFSDGLASLALLRQGMKDKSSHGVFEWNVTGASICYLGLESIFYFLVTLGLELMPVQKVMSFSIGEWWQNLKAFKQGAGSSSTEPLLKDSTGAISTDMEDDIDVQEERDRVISGLSDNTMLYLQNLRKVYPGDKHHGPKVAVQSLTFSVQAGECFGFLGTNGAGKTTTLSMLSGEETPTSGTAFIFGKDIVASPKAIRQHIGYCPQFDALFEYLTVKEHLELYARIKGVVDHRIDNVVTEKLVEFDLLKHSHKPSFTLSGGNKRKLSVAIAMIGDPPIVILDEPSTGMDPVAKRFMWDVISRLSTRSGKTAVILTTHSMNEAQALCTRIGIMVGGRLRCIGSPQHLKTRYGNHLELEVKPNEVSNVELENFCQIIQQWLFNVPTQPRSLLGDLEVCIGVSDSITPDTASASEISLSPEMVQRIAKFLGNEQRVSTLVPPLPEEDVRFDDQLSEQLFRDGGIPLPIFAEWWLTKEKFSALDSFIQSSFPGATFKSCNGLSIKYQLPFGEGGLSLADAFGHLERNRNRLGIAEYSISQSTLETIFNHFAANS
What are the official names of this protein?
ABC transporter A family member 1, ABC transporter ABCA.1, AtABCA1, ABC one homolog protein 1, AtAOH1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family. CPR flippase (TC 3.A.1.211) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPEE_SYNS3
Sequence: MTTAPETSGNWIDEHHNGVRYGLEGRVLVEETSPFQRITVIDSQRYGKGLLLDGCWMTAEHQERHYHEALVHPALCSAKAIERVLVIGGGDGGTARECLRYPGVKHLDMVEIDGRVVDLSQEHLPSIGGGCWHDPRFHLTIGDGIAWAAEAENAFYDVVLVDGSDPTGPAEGLFNRAFFSNCCRILKPGGVFATQSESPEAFRQVHIDMVKLIRELFGHADPLYGWVPMYPSGWWSWTFAAKDAPRYLTVQSERAAAVAEGSAIWSPRWQQGAFNTIPAFIERELNQ
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_MALP2
Sequence: MNKVFIVGRLAQDPQQFVTQNGITQSRISIASSDNWNKNETYFFPCVAWQSTANFINSYLHKGDLVAIDGKLIRRSYVSKEGKTVYVIEIVIESIKPLSSKNSNNAASSIDKNYNPTNTKNNNYSQQSNMSVSEAMDDFESNFAQKTSSTNITSKNEEKETFKDDPFALNDDEDPDQVVSLDWLDEFKE
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: GPSB_BACHK
Sequence: MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFEQLKQQNARLKRELEEQKLAATQVPQQPVVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: KHSE_STRZT
Sequence: MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQIGKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLGQLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIPNYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYRQDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPIIKAELEKQPFKGKLHDLRVDTQGVRVEAK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_YERPE
Sequence: MDQKFAVFGNPISHSKSPRIHTLFSEQTGIEHRYGKVLAPSEAFENTLVSFFADGAQGANITTPFKERAYDQCDELTDRASLAGAVNTIKRLEDGRLLGDNTDGIGLLSDLERQNLIRTTDHILLVGAGGAARGVILPLLSYGCTVVVTNRTHTRAQQLAKVFNHIGDIDVCEMSELAGQRFDLVINATASGLHGEVPNLPAAILTSQTRCYDMFYQAGTTPFLAWAQRLGLADYADGLGMLVGQAAHAFKLWHGVMPEITPVLAQLRSELGK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MATRX_PI1HC
Sequence: MAETYRFPRFSHEENGTVEPLPLKTGPDKKAIPHIRIVKVGDPPKHGVRYLDVLLLGFFETPKQGPLSGSISDLTESTSYSICGSGSLPIGIAKYYGTDQELLKACIDLKITVRRTVRSGEMIVYMVDSIHAPLLPWSGRLRQGMIYNANKVALAPQCLPVDKDIRFRVVFVNGTSLGTITIAKVPKTLADLALPNSISVNLLVTLKAGVSTEQKGILPVLDDDGEKKLNFMVHLGIIRRKVGKIYSVEYCKNKIEKMKLIFSLGLVGGISFHVHATGTLSKTLMSQLAWKKAVCYPLMDVNPHMNLVIWAASVEITSVDAVFQPAIPKEFRYYPNVVAKSIGKIRKI
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: WNT3B_PLEJO
Sequence: SGSCEVKTCWWAQPDFRAIGDYLKDKYDSASEMAVEKHRESRGWVETLRARYALFKPPTERDLVYYEGSPNFCEPNPETGSFGTKDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-3b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: APAG_BRUA2
Sequence: MYSAVTRGIEVTVEPFYLEVQSEPEENRYVWGYRVTIVNNSSETVQLCSRYWQITDANGHVQEVRGSGVVGKQPVLDPGDSYQYSSGCPLTTSSGVMVGRYQMKGEDGAQFEIEIPAFSLDVPEQRRTLN
What are the official names of this protein?
Protein ApaG.
Protein: MURG_METCA
Sequence: MARRIVILAGGTGGHVFPALAVAGKLRRAGAEVFWMGTRTGLEARVVPAAGYPIDWLSVSGIRGKGLASKAKAPAMLGLACLQALRILRRRKPDAVLGMGGFVAGPGGLMARVLGIPLIIHEQNRIPGTTNRWLSRIANRVLEAFPGAFQASAGAVCTGNPLRQGIETFRDHHTPRVGRHVLVLGGSLGAQALNRIVPRALARLGGEPVAIRHQTGQAMFQETQDLYQQLALTAKVDPFIEDMEEAYGWADLAICRAGAMTVSELAAAGLPAILVPFPYAIDDHQTANADYLAEAGAAVLMPQSSLDEVSLAVEIRALLDQRDRLEAMSAAARNLARYDAAESVAKVCLEEAGA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ZCCHL_HUMAN
Sequence: MAEPTVCSFLTKVLCAHGGRMFLKDLRGHVELSEARLRDVLQRAGPERFLLQEVETQEGLGDAEAEAAAGAVGGGGTSAWRVVAVSSVRLCARYQRGECQACDQLHFCRRHMLGKCPNRDCWSTCTLSHDIHTPVNMQVLKSHGLFGLNENQLRILLLQNDPCLLPEVCLLYNKGEALYGYCNLKDKCNKFHVCKSFVKGECKLQTCKRSHQLIHAASLKLLQDQGLNIPSVVNFQIISTYKHMKLHKMLENTDNSSPSTEHSQGLEKQGVHAAGAAEAGPLASVPAQSAKKPCPVSCEK
What are the official names of this protein?
Zinc finger CCCH-type antiviral protein 1-like.
Protein: Y3645_PSESM
Sequence: MMKGGMAGLMKQAQQMQEKMAKMQEELANAEVTGQSGAGLVSVVMTGRHDVKRINLDDSLMQEDKEVLEDLIAAAVNDAVRKIEQASQDKTASMTAGMQLPPGMKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PSPTO_3645.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y1151_ARCFU
Sequence: MRQTILKLYEKANERDWKPWELQSEMRKIYENVVAVGDDLSFTVRLDKDVKPVSLEKFGASKVKLHPFKTAWRFERGFIAFEGKFLRISREIDKKLLEEILSVILPED
What are the official names of this protein?
Uncharacterized protein AF_1151.
Protein: RL6_LISMC
Sequence: MSRIGKKTIVIPAGVTVTLNGSTATVKGPKGELVKEFNPEITINIEGNEINVSRPTDNKNHRALHGTTRAILNNMVVGVSEGYEKKLELIGVGYRAQKQGDKLVLNVGYSHPVEFVAPKGVDIEVPANTQVIVKGYNKEHVGELAANIRAVRPPEPYKGKGIRYEGEHVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ATPG_CLOPE
Sequence: MAGAGLLEIKRRIKSIKNTRKITKAMGLVATSKLRKARQKLTENNQYFSSLDEIARELIGSLNSNNNPLLKPNDNPKKLIILLASDSGLCGGFNGNTAAFVRDNYENNLENIEAVVVGKKGIHYVKKNKISTLAEYVDLGDTPNVGDASTIVNKAVKEFTDGNFGEVSLVYTKFFSPVKQEVVEEKLLPLDLTGEKGKVSFLIEPDEDEIIDSLVSSYLKGKFMNAMFNSKASEQSARMQAMDGATKNADDLLNSLDAKYNRIRQSIITQEISEIVGGAEAQK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCA_SHEFN
Sequence: MKIYLVGGAVRDTLLKQTVVDKDYVVVGSSVEEMLALGYQQVGKDFPVFLHPKTQQEYALARTERKTGYGYQGFSCDANKDVTLSEDLLRRDLTINAIAQDEHGTLTDPFHGIADINAKILRHVSDAFTEDPLRVLRVARFAARFHHLGFTIAPETLQLMTDIANSGELDHLTPERVWQECDKALSSQSPQVFFDVLKQCQALIVLFPEVDALFGVPQPEKWHPEIDTGIHTLMVLEQTSLLSDNKAVRFAALVHDLGKALTPKQDWPKHYGHGQKGLPVIKKLCARIRVPNEYRDLALLVSDQHQNIHNAFELRAETIVKLFDKGDFWRKPQRLTELLLCCHGDLRGRTGFEQSSYPQAEYLLHCYELASNVDVQSIIAAGYQGSQIKSQLQLNRAETINNYKIQYIESKQLH
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: Y4RC_SINFN
Sequence: MTKHASLAPLLESFFLQRLMQQRQASPHTISSYRDTFRQLLKFAERRLRKPPSRLNFEEIDAPLIVAFLDDLENRQGISVRSRNLRLTAIHSFFRYAAFEIPEHSAQIQRVLAIPSKRFTRTLVNFLTRPEVDALLAAPDRSTWSGRRDHAFLLVAVQTGLRLSEITGLKRDDLFFGTGAHLRVIGKGRKERCTPFAKSTTAVLRNWLKEPQRGDQGILFPSARGERLSVHGVQYMLNKHRQIASAMSPSLEGKRVTVHRLRHTMAMDLLQAGVDRAVIALWLGHESVETTQIYLEATLAMKEAALAKTSPYSGKSSRFRPDDNLLAFLNSL
What are the official names of this protein?
Putative integrase/recombinase y4rC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: OLSB_RHIME
Sequence: MTIELLDSMGVVDTSNAYIRKAVAAPASDVLGRIANLETRLARSAAEIDAAQAVRYRVFVEEMKAQVAPEAGRRKRDIDSWDAICDHLLVLDTSIEGDAEEQIVGTYRLLRQDVAERTGGFYSASEFAIGELLSRHPGKRFMELGRSCVLPEYRTKRTVELLWQGNWAYALKHGIDAMFGCGSFPGVVPEEHALALSFLHHNVRVRDEWAVSARPELYRTMDLMPPEAINPKKALAALPPLIKGYMRLGAMVGDGAVVDQAFRTTDVLIVLPIGKISGRYLNYYGADAGRFSSPVS
What is the function of this protein?
Catalyzes the first step in the biosynthesis of ornithine lipids, which are phosphorus-free membrane lipids.  Catalyzes the 3-hydroxyacyl-acyl carrier protein-dependent acylation of ornithine to form lyso-ornithine lipid (LOL).
What are the official names of this protein?
L-ornithine N(alpha)-acyltransferase, Ornithine lipid synthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. OlsB subfamily.
Protein: SSRP_RICBR
Sequence: MMEYKKIIAQNKKALFNYFIEERLEAGIVLKGSEVQSLRQGKASIEESHAADTGNEVFLYNCHIAEYEKANRFNHSTRRPRKLLLHKKEINKIIGRTKIKGYTLVALSMYFNKKNKIKIELGIAKGKKLHDKRESIKEKDWKRDQSRLIRQK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: THI20_YEAST
Sequence: MTYSTVSINTPPPYLTLACNEKLPTVLSIAGTDPSGGAGIEADVKTITAHRCYAMTCITALNAQTPVKVYSINNTPKEVVFQTLESNLKDMKCNVIKTGMLTAAAIEVLHEKLLQLGENRPKLVVDPVLVATSGSSLAGKDIVSLITEKVAPFADILTPNIPECYKLLGEERKVNGLQDIFQIAKDLAKITKCSNILVKGGHIPWNDEKEKYITDVLFLGAEQKFIIFKGNFVNTTHTHGTGCTLASAIASNLARGYSLPQSVYGGIEYVQNAVAIGCDVTKETVKDNGPINHVYAVEIPLEKMLSDECFTASDVIPKKPLKSAADKIPGGNFYEYLINHPKVKPHWDSYINHEFVKKVADGTLERKKFQFFIEQDYAYLVDYARVHCIAGSKAPCLEDMEKELVIVGGVRTEMGQHEKRLKEVFGVKDPDYFQKIKRGPALRAYSRYFNDVSRRGNWQELVASLTPCLMGYGEALTKMKGKVTAPEGSVYHEWCETYASSWYREAMDEGEKLLNHILETYPPEQLDTLVTIYAEVCELETNFWTAALEYE
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and also probably that of HMP to HMP-P.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thiaminase-2 family.
Protein: YMDB_SALNS
Sequence: MTSRLQVIQGDITQLSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSIAFPAISTGVYGYPRAQAAEIAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLTQQGDDPA
What is the function of this protein?
Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate.  Down-regulates ribonuclease 3 (RNase III) activity.  Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.
What are the official names of this protein?
O-acetyl-ADP-ribose deacetylase, Regulator of RNase III activity.
What is the protein family that this protein belongs to?
Belongs to the YmdB family.
Protein: Y241_METJA
Sequence: MKVVGLTKKIMEHLKEPITIKELAKKLNMHPKNLDVKIRVLRDLGLVETKKGRNGGVRLTKEGLYLLEKGEITLGSLKLQIVAKDRIGLLADITSRISKIGGNITSTVLEREGDEVIIYLVVENVDKDEIKNTLEDVVEKISILW
What are the official names of this protein?
Uncharacterized protein MJ0241.
Protein: RL4_PARDP
Sequence: MKLDVITLDAGKAGDIDLSDDIFGLEPRADLLHRVVRWQRAKAQAGTHSVLGKSDVSYSTKKIYRQKGTGGARHGSRKAPIFRHGGVYKGPTPRSHAFDLPKKVRALGLKHALSAKAAAGELVVVDSLNIAEAKTAAVAKAVKENGWKRVLVIDGAEVNENFARAARNLEGVDVLPSMGANVYDILRRDTLVLTRAGVEALEARLK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: GPTC2_MOUSE
Sequence: MFGADGRPAIGTAAGKSWHFSRTMEELVHDLVSALEESSEQARGGFAETGEHSRNLSCPLKRQARKRRGRKRRSYNVHHPWETGHCLSEGSDSSLEEPSKDYREKHSNNKKDRSDSDDQMLVAKRRPSSNLSSSVRGKRLLWHESDFAVDSLGNRTLRRRRKVKRMAVDLPQDVSSKRTMTQLPEGCRDQDMDNDRASQYPEFTRKKVKKRKLKGIRPGPKTQEEGGVLESEERSQPNKDRMEYEEQKASDELRSESDTSSLSSTDAGLFTNDEGRQGDDEQSDWFYEKESGGACGIAGVVPWWEKDEPAELDTNLPDPVFESILSGSFPLMSHPGRGGFQARLSRLHGTPSKNIKKSSGAPPSMLSAPGPGSNKRMVHFSPDAHRHDHWFSPGARTEHGQHQLLRDNRAERGHKKSCSLKTASRQTSMHLGSLCTGDIKRRRKAAPLPGPTAAGIVGENAQPILESNIGNRMLQSMGWTPGSGLGRDGRGIAEPVQAVQRPKGLGLGFPLPKSSPTSPAPTSGNPA
What is the function of this protein?
Enhances the ATPase activity of DHX15 in vitro.
What are the official names of this protein?
G patch domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleolus.
Protein: GRM4_RAT
Sequence: MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQKSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIAATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALATKQTYVTYTNHAI
What is the function of this protein?
G-protein coupled receptor for glutamate.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Signaling inhibits adenylate cyclase activity.
What are the official names of this protein?
Metabotropic glutamate receptor 4, mGluR4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCH4_CHRSD
Sequence: MQEPKNSQTLHDVANGASDLEGPLAWVGMEDIALPFRLANSAVNGRASAGVSLDATSARGIHMSRLYLALEALEHEEVTLSGLGAVLQRFLASHDGLARTAFLDLSGDVLIKRPALISPRAGWKAYPCALRCRQDTQGMQAVLEVTIGYSSTCPCSAALARQSIQQAFDEDFTDMPISHEAVRTWLGSEQGILATPHSQRSQAHLSLRLADDLETLPVTALIDTVEDALGTALQTAVKRVDEQAFALANGQNLMFCEDAARRVRHALQARDEVQGFRVRIVHAESLHAHDAVAHAEWNWTPNSP
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: ATPD_BRUA1
Sequence: MAETSSLISGVAQRYAGSLFEHALDANSVASVEKDLGRFEALLSGSEDLRRLISSPVFSSEDQLHAIGAIADKAGIKGLVGNFLRVVAQNRRLFALPGIIAAFRQIAAEHRGEISADVVSAHELTSAQQNELKATLKGVAGKDVTINVTVDPSILGGLIVKMGSRQIDTSLRTKLSSLKLALKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL14_LACDA
Sequence: MIQTETRLKVADNSGARELLVIRVMGGSKRKTGNIGDIVVAAVKQATPGGVVKKGDVVKAVIVRTKSGARREDGSYIKFDENAAVIINADKSPRGTRIFGPVARELREGDFMKIVSLAHEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y363_LISMO
Sequence: MKNLFLTSSFKDVVPLFTEFESNLQGKTVTFIPTASTVEEVTFYVEAGKKALESLGLLVEELDIATESLGEITTKLRKNDFIYVTGGNTFFLLQELKRTGADKLILEEIAAGKLYIGESAGAVITSPNIAYIQTMDSTKKAVNLTNYDALNLVDFSTLPHYNNTPFKEITQKIVTEYAGKSQIYPISNHEAIFIRGKEVITKRLS
What are the official names of this protein?
Uncharacterized peptidase Lmo0363.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
Protein: Y1889_STRPF
Sequence: MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVGYVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK
What are the official names of this protein?
UPF0297 protein MGAS10750_Spy1889.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.