PharMolix/UniProtQA huggingface dataset:
Protein: LTND_ECOLI
Sequence: MKTGSEFHVGIVGLGSMGMGAALSYVRAGLSTWGADLNSNACATLKEAGACGVSDNAATFAEKLDALLVLVVNAAQVKQVLFGETGVAQHLKPGTAVMVSSTIASADAQEIATALAGFDLEMLDAPVSGGAVKAANGEMTVMASGSDIAFERLAPVLEAVAGKVYRIGAEPGLGSTVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTNAAGNSWMFENRMRHVVDGDYTPHSAVDIFVKDLGLVADTAKALHFPLPLASTALNMFTSASNAGYGKEDDSAVIKIFSGITLPGAKS
What is the function of this protein?
Catalyzes oxidation of L-threonate to 2-oxo-tetronate.  Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
What are the official names of this protein?
L-threonate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. L-threonate dehydrogenase subfamily.
Protein: Y1856_MYCTU
Sequence: MEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG
What are the official names of this protein?
Putative oxidoreductase Rv1856c.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ATPB_MACCJ
Sequence: MAVGHVIQVMGPVIDVRFEHGQLPALNNALTLDIERGEGNTTKLTLEVALHLGDDAVRTIAMSSTDGVQRGAQVTDTGAPISVPVGDATLGRVFNVLGEKIDLEPELDGTVRRDPIHRQAPKFEELSTKVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLFHEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNVGSVTSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALTPAVVGEEHYEVARQVQATLQKYRELQDIIAILGMDELSDEDKKTVSRARRIQFFLSQNFHVAEQFTGQKGSYVPVKQTVQDFKAILEGKYDHIPEDAFRLVGGIEAVLEQAKGMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: INP5E_RAT
Sequence: MPSKSACLRHTEAPGQLEGRMLQGQLSNPEKKLIPTSASLPAADSQSSQTNSMPPLSMPAKPSNQNLQAKANLITPQPPIRPKLERTLSLDDKGWRRRRFRGSQEDLTVQNGASPCRGSLQDSVAQSPAYSRPLPCLSTSLQEIPKPRRATGSEGGSPSLWSDCLSGMISTSLDLLHREAASGGPHSRLASLRATHTPPAMDLNIASSSLRTANKVDPEHTDYKLRMQNRLVRAHSNLGPSRPRSPLAGDDHSIHSARSSFSLLAPIRTKDIRSRSYLEGSLLASGALLGADELARYFPDRNMALFVATWNMQGQKELPASLDEFLLPTEADYTQDLYVIGVQEGCSDRREWETRLQETLGPQYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYSTVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYNRTIQALALPRNVPDTNPYRSSAGDVTTRFDEVFWFGDFNFRLSGGRVAVEAFLKQDPEVDVLALLQHDQLTREMKKGSIFKGFEEAEIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYKSRHKGDICPMKYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLIGIKRRISKEIQRQEALKSQSSSAVCTVS
What is the function of this protein?
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate PtdIns (4,5)P2 and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity) (PubMed:10405344).  Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability (By similarity).
What are the official names of this protein?
Phosphatidylinositol polyphosphate 5-phosphatase type IV, 5-phosphatase that induces arborization, Pharbin, 72 kDa inositol polyphosphate 5-phosphatase, Inositol polyphosphate-5-phosphatase E, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type IV family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle. Cytoplasm. Nucleus. Note=Peripheral membrane protein associated with Golgi stacks.
Protein: PDUL_SHEPC
Sequence: MDHDLITKLTGQVIAQMRQRTIPLGISNRHVHLSAKDYQSLFPGQTLKIKKPLGQPGQFAAEQTVSLIGPRGQLKNVRILGPLRGQTQVEISYTDARQIGLTAPLRLSGDLTGSVSVTLKSEAGEINLTEGVIIARRHIHMSPLDAAIFGVTQGETVKVGIEGTDRKLIFDDVCIRVAEDMRLEMHIDTDEANAAGIDGGQAVARLLLTKR
What is the function of this protein?
Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
What are the official names of this protein?
Phosphate propanoyltransferase, Phosphate acyltransferase PduL, Phosphotransacylase PduL, PTAC, Propanediol utilization protein PduL.
What is the protein family that this protein belongs to?
Belongs to the PduL family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: COBQ_SALCH
Sequence: MTQAVMLQGTASDVGKSVLAAGLCRIFYQDGLRTAPFKSQNMALNSGITSDGKEMGRAQIFQAEAAGITPDVRMNPVLLKPTSDRQAQVVLMGKVATNMDAVSYHDYKPRLREQILAVYNSLAQEYDVIVLEGAGSPAEINLRDRDIVNMGMAEMAQCPVILVADIDRGGVFAAIYGTLALLHKQERDRVKGVIINKFRGDVALLYSGIEQIESLTGVPVLGVMPWLDVDLEDEDGVALQNDKYRGNAPRDITIAIVQLPHISNFTDFNALAAQPDVRIRYIRRPEALTDADLVILPGSKNTLSDLAWLRESGMADAVLQTHRQGVPVMGICGGYQMLGDTIVDEVESGLGTQPGLGLLNTITRFAQDKITTQVNATMSGELPSWLAAAAGLPVRGYEIHMGETVLQEGCCTAMTLQKNGCSVADGAVTADGLAFGTYLHGLFDSDAFTRAVVNGLRARKGLAPWETTFCYAEHKARQFDLLAEAMRQHIDIDKIYTIMQQHQEPV
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RECU_STRA3
Sequence: MVNYPHQLIRKTTVTKSKKKKIDFANRGMSFEAAINATNDYYLSHELAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYSGVYKGYYIDFEAKETRQKTAMPMKNFHAHQIEHMANVLQQKGICFVLLHFSTLKETYLLPANELISFYQIDKGNKSMPIDYIRKNGFFVKESAFPQVPYLDIIEEKLLGGDYN
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1G_DANRE
Sequence: MAAGTLYTYPENWRAFKAQIAAQYSGARLKIASAPPAFTFGQTNRSPAFLGNFPLGKVPAYQGDDGFCLFESNAIAHYLSNDVLRGSTPQASAQVLQWVSFADSEVIPPASAWVFPTLGIMQFNKQATEQAKEEVKRVLAVLNQHLNTRTFLVGERISLADITVVCSLLWLYKQVLEPAFRQPYPNVTRWFVTCVNQPQFKTVLGEVKLCEKMAQFDAKKFAEMQPKKEAPIKKEKGGKEGGKQQPQQQEKKEKKKEEKKAAPAEEEMDECEAALASEPKAKDPFAHLPKSSFVMDEFKRKYSNEDTMTVALPYFWDHFDREGFSIWYAEYRFPEELTMAFMSCNLITGMFQRLDKLRKNAFASVILFGANNDSCISGIWVFRGQDLAFPLSDDWQIDYESYTWRKLDVDSEECKTMVKEYFAWEGEFKHVGKPFNQGKIFK
What is the function of this protein?
Probably plays a role in anchoring the complex to other cellular components.
What are the official names of this protein?
Elongation factor 1-gamma, EF-1-gamma, eEF-1B gamma.
Protein: RL3_PSEA6
Sequence: MAIGLIGRKVGMTRIFTEDGVSIPVTVIEATPNRVTQLRTDETDGYTALQVTAGDKKANRVNKAAAGHFAKAGVEAGRGLWEFRLDGNEGEGIEVGSEITVEIFAETKMVDVAGTSKGKGFQGAIKRWNFSHQRNSHGNSLSHRAPGSIGQNQSPGKVFKGKKMAGQMGNKRVTVQSLDVVRVDAENNLLLVRGNVPGAPGGDVIIKAAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CP2G1_RABIT
Sequence: MELGGAFTIFLALCFSCLLILIAWKRVQKPGRLPPGPTPIPFLGNLLQVRTDATFQSFLKLREKYGPVFTVYMGPRPVVILCGHEAVKEALVDRADEFSGRGELASVERNFQGHGVALANGERWRILRRFSLTILRDFGMGKRSIEERIQEEAGYLLEEFRKTKGAPIDPTFFLSRTVSNVISSVVFGSRFDYEDKQFLSLLRMINESFIEMSTPWAQLYDMYSGVMQYLPGRHNRIYYLIEELKDFIAARVKVNEASLDPQNPRDFIDCFLIKMHQDKNNPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLIMKHPEVQTKIYEEINQVIGPHRIPSVDDRVKMPFTDAVIHEIQRLTDIVPMGVPHNVIRDTHFRGYLLPKGTDVFPLLGSVLKDPKYFCHPDDFYPQHFLDEQGRFKKNEAFVPFSSGKRICLGEAMARMELFLYFTSILQNFSLHPLVPPVNIDITPKISGFGNIPPTYELCLIAR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  This isozyme seems to be implicated in olfaction.
What are the official names of this protein?
Cytochrome P450 2G1, CYPIIG1, Cytochrome P450 olfactive, Cytochrome P450-NMB.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RNFB_PSEAB
Sequence: MNGVFLAIGALLPICLAGGALLGYAAVRFRVQGDPVAEQVNALLPQTQCGQCGYPGCKPYAEAIAAGDKINKCPPGGEATIRALADLLDLEPEPLDAAEETPPRVAYIREAECIGCTKCIQACPVDAIVGAARLMHTVIADECTGCDLCLEPCPVDCIEMRETPDDVRHWKWPQPSPRLIASDRERAA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: ARP3_ACACA
Sequence: MSRSGLPAVVIDNGTGYTKMGYAGNTEPQYIIPTAIATKGIAEDPRCRARRWWCPWAAGKNIADLDFFIGDEAYENSKVYQITMPVRHGQVENWTHMEQFWEHCIFKYLRCEPEDHHFLLTEPPLNAPENREYTAEIMFETFNVPGLYIAVQAVLALAASWTSKQVTEKTLTGTVIDSGDGVTHVIPVAEGYVIGSSIKHIPLAGRDITNFVLQLLRERNEKIPPAETLEVAKRIKETFSYVCPDIVKEFKKYDTEPDKWFKTYEGIESVGKKPYNVDVGYERFLGPEIFFNPEIFSSDFLTPLPKVVDETIQSCPIDTRRGLYKNIVLSGGSTMFKDFGKRLQRDIKRAVDYRIKRSEELSQGRIKSKAVDVKVISHHMQRFAVWFGGSMLASTPEFYKVCHTKQQYDEVGPSICRHNPVFGAMTM
What is the function of this protein?
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the pointed end of the daughter actin filament (By similarity).
What are the official names of this protein?
Actin-related protein 3, Actin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection.
Protein: TSAD_RICB8
Sequence: MKKILGIESSCDDTSVSIITEDREILSNIVISQNTEHADYKGVVPEIAARSHLANLEKAMKQALLESNTSLDEITAIAATSGPGLIGGVIVGSMFAKSLSSVLNKPFIAVNHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAVGEAFDKVAKMLDLPFPGGPKIEKRAKLGDPYKYKFPKPIINSGDCNMSFSGLKTAVRTLIMSLQEINDTIINDIAASFQFTIGEILSSKILEAIKVYEQITNDFNRNIVIAGGVAANKYLQELLSNCTKIHGYQLIYPPTTLCTDNAAMIAYAGLERYNNGLFTPLNFCPKARWSLEEI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPR1_HUMAN
Sequence: MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPRDYSGYQRDGYQQNFKRGSGQSGPRGAPRGRGGPPRPNRGMPQMNTQQVN
What is the function of this protein?
mRNA-binding protein that acts as a regulator of mRNAs transport, translation and/or stability, and which is involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types (PubMed:17210633, PubMed:31439799).  Acts as an mRNA regulator by mediating formation of some phase-separated membraneless compartment: undergoes liquid-liquid phase separation upon binding to target mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors (PubMed:31439799, PubMed:34074792, PubMed:36040869).  Undergoes liquid-liquid phase separation following phosphorylation and interaction with FMR1, promoting formation of cytoplasmic ribonucleoprotein granules that concentrate mRNAs with factors that inhibit translation and mediate deadenylation of target mRNAs (PubMed:31439799).  In these cytoplasmic ribonucleoprotein granules, CAPRIN1 mediates recruitment of CNOT7 deadenylase, leading to mRNA deadenylation and degradation (PubMed:31439799).  Binds directly and selectively to MYC and CCND2 mRNAs (PubMed:17210633).  In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs (PubMed:17210633).
What are the official names of this protein?
Caprin-1, Cell cycle-associated protein 1, Cytoplasmic activation- and proliferation-associated protein 1, GPI-anchored membrane protein 1, GPI-anchored protein p137, GPI-p137, p137GPI, Membrane component chromosome 11 surface marker 1, RNA granule protein 105.
What is the protein family that this protein belongs to?
Belongs to the caprin family.
Protein: NU6M_DUGDU
Sequence: MMYTVFVMSVLFVVGFVGVSSKPSPVYGGLGLVASGGVGCGIVVSFGGSFLGLMVFLVYLGGMMVVFGYTTAMATDEYPEAWGSNIVVLGALVGGLLMEGAAVVYLFSGGGLELVGLDLGSLENWMVFGGEGEELIREDYVGGSSLYSYGCWFMVMSGWMLFISVFIVIEVTRGR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: QUEA_NITEC
Sequence: MKTDDFDFSLPNELIAQLPLANRADSRMLYINSRQSDLRDAAFKDLPAYLKQGDVIVFNNTRVVKARLAGFKSTGGKVEVMIERILGTHQARALIRASHAPAIGSTLLLENAITVQVEAREQDIYTLRFIHSQPLIELLDQYGHTPLPPYIGRIATASDESRYQTVFAQETGAVAAPTAGLHFDETMLTTLQTLGIKIAWVTLHVGAGTFQPVRVENINQHIMHTEQYHIPTETIEIIRRCKAGGGSVLAVGTTSLRALEASALIGDGELVAGSNETNLFITPGFQFRVVDRLLTNFHLPRSTLLMLVSAFAGIETIRHAYQHAVNNHYRFFSYGDAMLIEGDSRS
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CROS5
Sequence: MRHRCRVPQLGKAADQRKALLRSLTTELIRHGQIKTTKTRAKAVRSEVERMITLAKDGSLSARRRAIGYLYDKQLVHALFAEAPERYSNRKGGYTRIVRTLRRRGDNAEMAIIELM
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RS14Z_STRMU
Sequence: MAKKSMVAKSKRPAKFSTQAYTRCEKCGRPHSVYRKFKLCRVCFRELAYKGQIPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RS7_CHLSY
Sequence: MPRRGNIERRPIPPDARYNSVLVQKFINKVMERGKKSLAERIVYQALDLAAERLKKPQMEIFEQALRNASPSIEVRPKRVGGATYQVPVEVKSDRRYSLAMRWLLMSARARTGKPMVERLAAELIDAYNNTGTTIKRKEDVHRMAEANRAFAHYGRL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CD045_BOVIN
Sequence: MACVTFREPISATVGKRMVFTGPAYVKDHLPQVAQHTAYIGEKRPALEKTGDLRYLWRPASNRSLPAKYKPEYVGEIGWGIPEYDFINKTRLQTGFHIKYEEFSQAAIDKLSHRYQSPWQPNPSIMDAEGSSSRGFIAWHMGDYEDTSQRNSKRAVLLRQSKAALPIGSRPPKLPKLPKKEEKSKFRPLHQHDARCY
What are the official names of this protein?
Uncharacterized protein C4orf45 homolog.
Protein: TDIF_ZINVI
Sequence: MDIDLLWSFGGWFFILFPETINYCMAKLRSTSQISHFTNPRSCSSLFFVALLIITILITMLQSSTSMEVTSLPTHQPTSSNSHDESSTSSTATTTTDLHPKRTHHQSHPKPTRSFEAGAHEVPSGPNPISNR
What is the function of this protein?
Extracellular signal peptide that regulates cell fate.  Represses tracheary element differentiation but promotes the formation of procambial cells adjacent to phloem cells in the veins.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein TDIF, Tracheary element differentiation inhibitory factor.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[TDIFp]: Secreted, extracellular space. SUBCELLULAR LOCATION: [CLAVATA3/ESR (CLE)-related protein TDIF]: Cell membrane; Single-pass membrane protein.
Protein: DLTC_STRZJ
Sequence: MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVEIENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDRP_RAT
Sequence: MWKLSRSRVLLDEPPEEEDVLRGASPASAAAQAPGASLRGWKEATSLFNKDDEERLLETSRSSKSKGTNVRLKEELKAEKKSGFWDALVLKQNVQPKKPDQMEGWEPPKLTAEDVATDHTEDGISSLPPWSAWEDDTKGSTKYTSLASSASSSRWSLRSAGKLVSIRRQSKGHLTETCEEVE
What is the function of this protein?
Contributes to normal sperm motility, but not essential for male fertility.
What are the official names of this protein?
Testis development-related protein.
What is the protein family that this protein belongs to?
Belongs to the TDRP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear. Also detected in cytoplasm near the midpiece of the flagellum.
Protein: MMP12_RABIT
Sequence: MKFLLLILTLWVTSSGADPLKENDMLFAENYLENFYGLKVERIPMTKMKTNRNFIEEKVQEMQQFLGLNVTGQLDTSTLEMMHKPRCGVPDVYHFKTMPGRPVWRKHYITYRIKNYTPDMKREDVEYAIQKAFQVWSDVTPLKFRKITTGKADIMILFASGAHGDYGAFDGRGGVIAHAFGPGPGIGGDTHFDEDEIWSKSYKGTNLFLVAVHELGHALGLDHSNDPKAIMFPTYGYIDLNTFHLSADDIRGIQSLYGGPEQHQPMPKPDNPEPTACDHNLKFDAVTTVGNKIFFFKDSFFWWKIPKSSTTSVRLISSLWPTLPSGIEAAYEIGDRHQVFLFKGDKFWLISHLRLQPNYPKSIHSLGFPDFVKKIDAAVFNPSLRKTYFFVDNLYWRYDERREVMDAGYPKLITKHFPGIGPKIDAVFYFQRYYYFFQGPNQLEYDTFSSRVTKKLKSNSWFDC
What is the function of this protein?
May be involved in tissue injury and remodeling.  Has significant elastolytic activity.  Can accept large and small amino acids at the P1' site, but has a preference for leucine.  Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity).
What are the official names of this protein?
Macrophage metalloelastase, MME, Matrix metalloproteinase-12, MMP-12.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HIS4_PARD8
Sequence: MIELIPAIDIIDGKCVRLTQGDYATKKVYNEDPLEVAKMFEGNGIRRLHVVDLDGAREGRIINYRILERIATRTSLIIDFGGGLKQEDDLEIAFESGAQMVTGGSIAVKNPEMFTSWISKFGSEKIILGADAKEKKIAISGWEETTSQELVPFIKGYYDKGITKVICTDIARDGMLQGPAIDLYKEIRDEIPFLYIIASGGVSSIEDIEKLSEAGIPAVIFGKAIYEGKIQLKDLLRFT
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM59_PONAB
Sequence: MAAPKGSLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHTYPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQLPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDVMDSAQSFITSSWTFYLQADDGKIVIFQSKPEIQYAPHLEQEPTNLRESSLSKMSYLQMRNSQVHRNFLEDGESDGFLRCLSLNSGWILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGDLEFMNEQKLNRYPASSLVVVRSKTEDHEEAGPLPTKVNLAHSEI
What is the function of this protein?
Acts as a regulator of autophagy in response to S. aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C).  Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy.  Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP.  Inhibits APP transport to the cell surface and further shedding.
What are the official names of this protein?
Transmembrane protein 59.
What is the protein family that this protein belongs to?
Belongs to the TMEM59 family.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Mainly localizes to late endosomes/lysosomes. Probably first exported to the cell surface and then actively endocytosed to transiently localize in early endosomes on its way to the late endosomal/lysosomal compartment where it becomes quickly degraded.