PharMolix/UniProtQA huggingface dataset:
Protein: BETB_ECO24
Sequence: MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGREDVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETSTVDIVTGADVLEYYAGLIPSLEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMMANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHRDNVLRYIVKGKEEGARVLCGGDVLKGDGLDNGAWVAPTVFTDCSDEMTIVREEIFGPVMSILTYESEEEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: GATB_THEYD
Sequence: MQYEAVIGLEVHAQLLTESKIFCGCSTQFGAEPNTQVCPVCLGMPGVLPVLNKKAVEYTVKTGLAMNCKIAPYSRFARKNYFYPDLPKGYQISQYELPLCEDGYLEIMLNGTKRKIRIKRIHLEEDAGKNIHDPSGYSFVDFNRTGVPLMEIVSEPDIRSPKEAALYMKKLRAILRYLGVCDGNLEQGSLRCDANVSVRPVGSTEFGVKTEIKNINSFRFVEKALEYEIKRQIKLIENGEKIIQETRLWDSQTGTTQSMRSKEEAHDYRYFPEPDLVPVVVSEDWIEKIKKDMPELPDQKIERFIKEYGLPQYDSEILTEEKALSEWFEEAVKLGGKPKEVANWIMVELLRLLNEEGKDINECSLKPIQLVELIELINKGTINRNTAKEVFEEMYKTGKTAEAIVREKGLTQISDDSVIIEAIKEVMNKNPKEVERFRNGEEKLIGFFVGQVMKITKGKANPKLVNELIFKILKE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: TOLC_ECOLI
Sequence: MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAALNVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTASTGISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPENVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN
What is the function of this protein?
Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC.  These systems are involved in export of antibiotics and other toxic compounds from the cell.  TolC is also involved in import of colicin E1 into the cells.
What are the official names of this protein?
Outer membrane protein TolC, Multidrug efflux pump subunit TolC, Outer membrane factor TolC.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: UBIC_NITEC
Sequence: MKANPPLAWHPVPVSAPVNLRWWLMHQESLTRLLQAHCEHFRVEPVFQTLATACIDELEVMNLRRQNQVLVREVYLRCNETPVVFAHSIVKKEHLRGAWRGLSRLGNRSLGTMLFTNPLIQRTPLAFKKLKPHHPLFERACKQLQMRPINLWARRSLFILLRQPILVTEVFLPAIHQL
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_RHIE6
Sequence: MIQTTFPDRAVMAELVAKMLWEIKAVHFNAGEPYKLSSGMASPVYIDCRKLLSYPRIRSTVMDFAASTLMRDAGFEQFDCIAGGETAGIPFAALLADRLGLPMIYVRKQPKGHGRNAQIEGNMPEGSRVLVIEDLTTAGGSMFKFIDAVRAAGGIVDHGIALFFYDIFGQQRFTDGKVRLHHIATWRNVLAVAKAQQLFDDKTLAEVEAFLDAPLAWSGRNGGVCELSL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: YAF2_CAEEL
Sequence: MRRKNGFSVASVFILCSIAQMTCEEFELENTESLVECVQCVQLWRSASAKEGKVCTSGATTCKGNACFMRQCKHCPVYQYMSGCVNFSPWQLADLEMNRRTSELRMRRVGAVLLCEDTFNQTTCVCNRRDKCNDIHSRLPFATYAEGLFRGVVNFDTIIAAIDPRYLEVMSGYHFRFLASSSSSFSSFLPSIAIILFFVLSH
What are the official names of this protein?
Uncharacterized protein F46C5.2.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ADA2C_DANRE
Sequence: MHNLSYASEEDTYTDTDFTPSGNSTNSTSYSPATIIGLAGLVSFLILFTIVGNVLVVIAVLTSRALKPPQNLFLVSLASADILVATLIIPFSLANELMGYWFFGEVWCNIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRNTVDERRPMCQLNDHTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRNMSEKRRDPDGGSGTPRLENGLSREDSRRENGHCSSSPGERKPAEDNPDADLEDSSSSDEKAKRSQNETAPSKKDRRSSRKNSSSSKHSSRKSRASSKSLDLFSSRRKRRNTISRKKISQAREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICREPCAIPDPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAFQKILCKSWKRSF
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.  The order of potency for this receptor is dexmedetomidine > norepinephrine > epinephrine.
What are the official names of this protein?
Alpha-2C adrenergic receptor, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TUSC1_MOUSE
Sequence: MWRMRGGATRRGSCGGEGGGSRGESGRLGRAREGGGGGGGVGWRGRAGGARRQLEERFADLAASHLEALRARDERDRQNARLREENARLRLENRRLRRENRSLFRQALRLPGDSGEREAAVETLAPDEPATNRKARGHGREEEPGSPRALRARLEKLEVMYRRALLQLHLEQQGARPPGAIEEPPLQETATGLCAHDPDVPRPWL
What are the official names of this protein?
Tumor suppressor candidate gene 1 protein homolog.
Protein: SURE_LARHH
Sequence: MRFLLSNDDGYFAPGIEALAAGLATLGTVTVVAPERDRSGASNSLTLDRPLMLRRAPNGFHFVNGTPTDCVHLAVTGMLDQQPDMVISGINHGANMGDDTVYSGTVAAATEGFLLGVPSLAVSLAAKPGEHLDTAVQVTLDIVRRMMDRPFTEPTLLNINVPDRPFHELRGTVATRLGRRHHAEPVVKSVNPRGDVVYWVGAAGPAQDAGEGTDFHAVREGFVSVTPLSIDLTGYRQLAELPAWLNP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECF_KORVE
Sequence: MELFRNTNIDFLGKKWYFLAFSLVFSVAGLISMGARYAKTGTAVPLGVDFKGGTLVYVKFAQTPNLGDIRAAMDRSGLKDPKIQTYGGPANNEVLIALEQKETSEQALDAGKNTIIKALETNPASGKNDLNNVGSTTIRDYLMSKDPLHEVVDPGAKYQQIASQIVDYRDKERGGVLSSVDELQGHVPADVVNALKTDYFTSGFGVRNVEIVGPQVGKQLSNQALLATLYSLGGMLVYLWFRFELIYGIGAVVACFHDTIITVGAFSLLNRDISLTVVAAILTLIGYSMNDTIVVYDRIRENIKLLRRESLADIVNKSINQTLSRTILTSGLTFLTVLSLYVFGGEVLRGFSLALVIGILIGTYSSIAVAAPMLVAYQEWRGHRGTAALPGPAPRKNDRVKVKA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRF_STRA5
Sequence: MLEKCPIIALDFSDLASVTTFLEHFPKEELLFVKIGMELYYSEGPSIIRYIKSLGHRIFLDLKLHDIPNTVRSSMSVLAKLGIDMTNVHAAGGVEMMKAAREGLGKGPILLAVTQLTSTSQEQMQVDQHINLSVVDSVCHYAQKAQEAGLDGVVASAQEGMQIKKQTNEHFICLTPGIRPPQTNQLDDQKRTMTPEQARIVGADYIVVGRPITKAENPYQAYLEIKEEWNRIK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SODM_RAT
Sequence: MLCRAACSAGRRLGPAASTAGSRHKHSLPDLPYDYGALEPHINAQIMQLHHSKHHATYVNNLNVTEEKYHEALAKGDVTTQVALQPALKFNGGGHINHSIFWTNLSPKGGGEPKGELLEAIKRDFGSFEKFKEKLTAVSVGVQGSGWGWLGFNKEQGRLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVSQRYIVCKK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LEU1_THEVB
Sequence: MRIKYPPQTVDRVLIFDTTLRDGEQSPGASLNVDEKLTIARQLARLGVDIIEAGFPFASPGDFEAVQRIAETVGTETGPVICGLARATRQDIEAAAKALKPAYYPRIHTFIATSDIHLEYKLRKTRAEVLEIAQEMVAYAKSFVDDVEFSPEDAGRSDPEFLYEVLERVIDAGATTVNIPDTVGYTTPAEFGALIKGIKENVPNIDRAVISVHGHNDLGLAVANFLEAVKNGARQLECTINGIGERAGNAALEELVMALYVRRQYFNPFLGRPPESEAPLTNINTREIYKTSRLVSNLTGMLIQPNKAIVGANAFAHQSGIHQDGVLKHKQTYEIMDAQLIGLADNQIVLGKLSGRNAFATRLRELGFELSETELNKAFLRFKDLADKKKEITDWDLEAIAKDETQGIDLQGYQLEFVQVSCGDHARPTATVTVRTPSGEELTDAAIGTGPVDAVYRAINRVVQIPNRLIEYSVQSVTAGIDAIGEVTIRLQHQDRIYSGHAANTDIIVASAQAYMNALNRLYRGLEQRALHPQA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: BECN1_GIBZE
Sequence: MNCQKCRQPLRLDGSLEDLNPAAYDVLVASASPQTLKKSSVPNPPLAQPQDQSRKSIYDRVSRNAGPPTFKRNHGSHPRDSSMSFVLLSESQMARPTPSSDPPTTPTVLRRASSSKSNADNPDAPMGSEMDRINRLFDVLSARSDVDHPICVECTEMLVEGLQKKLEIASRERDSYAKHLKEAKANKPSEEDMKTQEEALRKAERDRAAAMEELKKLESEKTSLDEELVLLEEESRQLDKEEEKFWRERNDFATRMADFQAERDSINAKYSNDSQLLEKLQRSNVYNDTFCISHDGSFATINGLRLGRLSNKPVDWPEINAAWGHALLLLVTVADKLAYRFDGYDPQPMGSTSRIIRYEVPSPSSSRLGTRAASVPPKRHILELYSSGDMPLGLTFMHRRFDNAMVGFLELVRQLGAFVHRQTEATGTPLSLPYKIDGDKIGDVSIKLGIAQDDGWTKACKLTLTCCKFLLAHASNVTSNARNGGSQ
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt), autophagy, nucleophagy, and mitophagy, as a part of the autophagy-specific VPS34 PI3-kinase complex I (By similarity).  This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure (By similarity).  Also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 30, Autophagy-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein. Note=With the VPS34 PI3-kinase complex I, localizes to the vacuole-isolation membrane contact site (VICS) during isolation membrane (IM) expansion (By similarity). The IM is a membrane sac generated from the pre-autophagosomal structure that ultimately expands to become a mature autophagosome (By similarity).
Protein: UNG_EHV1V
Sequence: MSSACDHETEASHVNIPETTPEENGSNSSTPTSEIGPACVVSPAPGETGAPPPKRRRPCGLPQGVALINTSVSTHPLFTTSCQSSWEDVEREFNIAPSWRPILEREMQQPYVRLLLNEYKLRCASEEVFPPKEDIFAWTRFSPPEKVRVVIVGQDPYHAPGQAHGLAFSVRKGVPVPPSLRNIYSAVQKSYPSFRHPMHGFLERWAEQGVLLINTTLTVARGKPGSHATLGWHRLVRAVIDRLCTTSQGLVFMLWGAHAQKSCSPNRQHHLVLTYGHPSPLSRVNFRDCPHFLEANAYLTKTGRKPVDWQIE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines.  Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG, UNG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CCSA_POPAL
Sequence: MIFLTLEHILTHISFSVVSIVIIIHFLTLLVNEFVGLYDSSEKGMLTTFFCLTGLLITRWIYSGHLPISDLYESLIFLSWIFSIIHMVPYFKKHKNYLSTITAPSTFFTQGFATWGLLTDMHQSKILVPALQSQWLIMHVSMMVSGYAALLCGSLLSAALLVITFRKVIRIVGKNNNLLNDSFPVDEIQYMMEKKSIFKNTFFPSSRNYYRFQLIQQLDHWGFRILSIGFLFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWTIFAIYFHTRTNKNLEGLNSAIVASIGFLIIWICYFGVNLLGIGLHSYGSFTLISN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HOX23_ORYSI
Sequence: MASNGAAAGAMAPFFPPNFLLQMQQPLPLHHQHLQDHAHGGHGGHHLLPPPPPSLSPFLPDLAMDAPPPPMYEASGGDGGGGGAASEDEEDGCGGGGGGGGGEKKRRLSVEQVRTLERSFESGNKLEPERKAQLARALGLQPRQVAIWFQNRRARWKTKQLEKDFDALRRQLDAARAENDALLSLNSKLHAEIVALKGGAAAAGGGGSSCRQEAASELINLNVKETEASCSNRSENSSEINLDISRPAPPPPPPPANESPVNRGIPFYASIGRGGAGGVDIDQLLLRGGHSPSPAAVTTPPPPKMELGITGNGGGADAAAAGAGSFGGLLCGAVDEQPPFWPWADGHHHFH
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX23, HD-ZIP protein HOX23, Homeodomain transcription factor HOX23, OsHox23.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPB_EHRRG
Sequence: MEWKIESLPVPYDKAMCFMQQRVEGIANKTQDELVWLLEHFPLYTAGTSARSEELLTDSLFPVYSTGRGGKYTYHGPGQRIAYVMMDLKARDKCNVRLYVETLGEWIVKTLKHFSIRSYFNPNLIGVWVNHNGSEKKIAAFGIRIRKWITYHGVSINVFTDLSHYSGIIPCGIKEYGITSLKTLGVNILYEEFDVVLKKEFNKVFCNC
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_CORGL
Sequence: MSEANVNNQEKSTRKVRTGYVVSDKMQKTIVVEVEDRKQHALYGKILRSAKKVKAHDEEQIAGIGDLVRIEETRPLSKDKNYRLIEIVEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: HIS3_GEOUR
Sequence: MIKLDFEKMGGLIPAVIQDHESGEVLMVAFMDEKTLNLTLETGKTWFFSRTRNKYWMKGEESGNTQEVKEVLTDCDADTVVIKVKQNGPAACHTGNRSCFYVKWENGEWVEHSNPLFDPNEVYKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_SYNS9
Sequence: MVALRLIPCLDVARGRVVKGINFVGLRDAGDPVELACRYSHAGADELVFLDIAASHEGRATLVDLVRRTAESVTIPFTVGGGISSVEGITELLRAGADKVSLNSSAVGRPELVREGAQRFGRQCIVVAIDARRRNSGTDGWDVYVKGGRENTGLDVVRWAQQVTELGAGEILLTSMDGDGTQAGYDLQLTRAVAAAVSVPVIASGGAGCLDHIAAALETGPEGGHASAALLASLLHDGVLTVEQIKADLLARGLKIRP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1532_BRUSI
Sequence: MTDKPFWQTKNLNQLTRSEWESLCDGCGQCCLHKLQDEDTDEIYWTSVACTLLNPETCQCRDYPNRKKTVPDCVFLTPEIVDEVDWLPVTCAYRLVAEGSDLYWWHPLVSGSPETVHEAGISVRGKVTAFDHDMQDDDDYLDHMVTPDKIAR
What are the official names of this protein?
UPF0260 protein BSUIS_A1532.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: LIME_DICDI
Sequence: MSASVKCGACAKTAYPLESVVANNNSYHKGCFKCSTCNSTLNVKTFKSFEGKLYCPVHTPKVSATAVTDSVALKNALNAPKKVAEGLGNAHRGLDEKPNIGLDSMATANALNAPKKVVEGLGNVQKGIGGKPTYAVFGADGQPTGEQQEQQQYTEEQYEQPQEEQQYQEEQQQYQEEEQQYQEEEQQYQEEEQQYEEEQ
What is the function of this protein?
Associates with the actin cytoskeleton and may regulate actin polymerization in lamellipodia, through a rac1-dependent signaling pathway.  May play a role in cell motility.  Involved in cytokinesis by regulating the microtubule system and linking it to the cortical actin network.
What are the official names of this protein?
LIM domain-containing protein E, DdLim.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Nucleus. Cell projection, lamellipodium. Cell projection, filopodium. Cytoplasm, cytoskeleton. Note=Weakly expressed in cytoplasm. Found in actin-rich protrusions, and lamellipodia and filopodia during motility.
Protein: NU4LM_BOSMU
Sequence: MSMVHMNIMMAFAVSLVGLLMYRSHLMSSLLCLEGMMLSLFVMAALTILNSHFTLASMMPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FADH_PSEPU
Sequence: MSGNRGVVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTAQVGLVLGHEITGEVIEKGRDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVNPARAGGAYGYVDMGDWTGGQAEYLLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAVTAGVGPGSTVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFEIADLSLDTPLHEQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVAGKIGIPGLYVTEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMWDRINIAEVVGVQVISLDDAPRGYGEFDAGVPKKFVIDPHKTFSAA
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of formaldehyde and acetaldehyde, and, to a lesser extent, long-chain alcohols, but is inactive against propionaldehyde, butyraldehyde, methanol and ethanol.  Can also catalyze the dismutation of a wide range of aldehydes such as formaldehyde.
What are the official names of this protein?
Glutathione-independent formaldehyde dehydrogenase, FALDH, FDH, Formaldehyde dismutase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: BLI1_VANPO
Sequence: MREQERKLSNGIEHCLSKTQEYVDMESAKAISIFSSKVNSNGRWLAEISGKYELKESGELEAFRLLKEDHVKMLDQLEGKIEYYEKLLDELTEFTSEIEIKRKIEKNRRSRHFNNV
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLI1, BLOC-1 subunit BLI1, BLOC-1 interactor 1.
What is the protein family that this protein belongs to?
Belongs to the BLI1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: PGK_ECOLI
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARL4D_PONAB
Sequence: MGNHLTEMAPTASSFLPHFQALHVVVIGLDSAGKTSLLYRLKFKEFVQSVPTKGFNTEKIRVPLGGSRGITFQVWDVGGQEKLRPLWRSYTRRTDGLVFVVDAAEAERLEEAKVELHRISRASDNQGVPVLVLANKQDQPGALSAAEVEKRLAVRELAAATLTHVQGCSAVDGLGLQQGLERLYEMILKRKKAARGGKKRR
What is the function of this protein?
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP).  GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit.  Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 4D, ADP-ribosylation factor-like protein 4L.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cell membrane. Nucleus. Cytoplasm.
Protein: COAE_CLOAB
Sequence: MLKIGLTGGIGSGKSTISRIFKERQILVVDADEVSKEVLKEHPEILTAVRNKFGDNFFDENGEFTRREFGNFIFNSEPHRKEYENIIMPYIKKDIVRTMKLYESLNENVCVLDAPTLIENDIYKDMDINILVWVDKATQIKRVQKRDGMSEDEVIMRINSQMSLEEKKKYVDFIIDNSGEFENTIKQIDRIMQSVSIMKGK
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.