PharMolix/UniProtQA huggingface dataset:
Protein: MURC_RHIWR
Sequence: MKGVATDIGTIHFIGIGGIGMSGIAEVMHNLGYKVQGSDVAESYVVEGLRKRGIAVMIGHKAENLGDAAVVVTSTAIKRGNPEVELALEKRVPVVRRAEMLAELMRLKSTVAIAGTHGKTTTTSMVAALLDAGGVDPTVINGGIINSYGSNARLGASDWMVVEADESDGSFLRLDGTIAVVTNIDPEHLDHYGSFDKVKDCFVEFVENVPFYGAALLCIDHPEVQAIIPRVRDRKVVTYGFSAQADVRGDNVTPIPGGNRFDVVVRNRDGDTRRIEGVTLPMPGRHNVQNALAAIGVALEMNISDAIIATGFAKFGGVKRRFTKVGEVPVGDGVATVIDDYGHHPVEIRAVLAAAREGARAKVIAVVQPHRFTRLRDLMTEFQTAFNDADTVYVAPVYAAGEAPIDGVDAAALVAGLKQRGHRSAQVIAGPEALAATLAATIAADDMVICLGAGDITKWAAGLSEAIAKETAR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_PSEPK
Sequence: MIDPDGFRPNVGIILTNDAGQVLWARRINQDAWQFPQGGINPDETPEDALYRELNEEVGLERDDVEILACTRGWLRYRLPQRLVRTHSQPLCIGQKQKWFLLRLVSNEQRVRMDLTGKPEFDGWRWVSYWYPLGQVVTFKREVYRRALKELAPRLLTRD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: ILVD_THET2
Sequence: MRSDQIKKGLKQAPARAMLRAVGVGDEDFGRPFVGVVNTFTDGMPCNFHLRELAQHLKAGLREAGLFPFEFGAPAISDGISMGTPGMRASLVSREVIADSVELIAQGYLYDGMVGLSACDKTIPGTAMGVIRSGVPGMVLYGGTIAPGEWQGRKLTIVEVFEAVGQRAAGKISEEELLEIERRAIPGPGACGGQYTANTMAMALEALGLSPVGYNAIPAVHPEKERATKEAGKILAWAIAHDWKPKDFLTRKSFLNAVAAVAATGGSTNAVLHLLALAKEAGVELSLDDFDQISRKTPVIADLRPWGTYTAWELYEAGGTALVFKRLLEAGLLFGEEKTLTGRTLAEEVERAYREQEGQKVVFPVEKALKPHGGLVVLKGNLAPQGAVLKLAGTERTSFEGPARVFDSEEAAMEKVLKGEIRPGDVVVIRYVGPKGAPGMPEMLSVTSAIVGEGLGPEVALLTDGRFSGGTRGLMIGHIAPEAFVGGPIALLEEGDRIRIDVEGRRLEVLLPEEELERRRARWRPRPPAFTHGLFARYAALVRQADEGAVLEDPL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CAS1A_THET8
Sequence: MTLHLTRQGATLRLRQGRLLLEEEGREVAGFPARQVRSVALWGNVRLSTPALVFLLRQGVPVFFYSLEGFLHGVAGAYPDPHPAHLRAQFAAEGLPLARAFVVGKLRSALALLERHRLPEAGGVVEALARAEGASELERLRGAEGEGSRVYFQGLARLLGPYGFGGRTRRPPRDPVNAALSYGYALLLGRVLVAVRLAGLHPEVGFLHAEGRRSPALALDLMEEFRVPVVDQVVLSAFRRGLLTPSHAEVREGGVYLNEEGRRRLIQLFEERLLEGVSHPLGFRKPLGETIEVQAQRLKAALLGRGRYTPFYLWR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: ATG9_VANPO
Sequence: MGDSESVNQDHGRNTFLSRVFGLQPDDITTSIRTGDMSRYPLNAYSGGSEMFSGSPTSSRIDDDDDDDEGRVPESDQQSSSGDNSDDIKANDDVIEDVELTDGNGDNYTNSKMINTNYSIFGSLRKVGQQSSDEEDDGSLSNEEEDIDEEDEIDEIDADEPLFVNSTSQRKQKRKSSVNFKNGSEMSSLLFQRILNKKDSKSNGEASNKMFTSSNQGNHNYKYRNGHDLEGGVHFNKKEGRRNSLFGSHEAGGHKSHNSAPSKGPNLLKNISILNNTPSNKVYTLSPKERALWKWANVENLDVFLQEVYKYYLGSGFSCIVLRKLLNLTTLIFVVYISTYLGYCIDYSKLPTSSRLSDIIIDQCYTTRITGITKGLLWVFYVFVGLKVVQFYFDLQNLTDMHNFYNYLLGISDNELQTIPWQNIIQQLMYLKDQNALTANVVEVKAKNKIDPLVVANRIMRKDNYLIALYNENILDLSLPIPFYKESILTKTLEWNINLCIIGFAFNESGFIKQSFLKKSQHQFITEELRKRFMLAGFLNIILSPFLVTYFVLLYFLRYFNEFKTSPGTIGARQYTPMAEWTFREFNELYHIFQKRLGLSTVIADKYINQFPKESTDLILKFISFISGSFVAVLMSLTLLDSENFLNFEVTKDRSVLFYITVFGAIWSVCRNSISDEYKVYDPDETIKELSEFTHYLPKEWEGKHHTEDVKQEFCKLYNIRLIILLRELASLVLTPFILWFSLPACSDRIVDFFSDSSTYIDGLGYVCKYATFGINQANAQKVKGGKRHQDMKMNTNNFSNEVINESDEDVLDSDSDSEIDSNDKMMRSYMYFMEDYENSENAIGKNQLPRKKYKDPSLTNPSLNTDYSWRKQFQPGQRPELFRIGKHALQVPTNVRNLGKKSTLNSENPYDNSSNLGESFINPTIMPDRDLGRNGVNGGKKEAGMLRMVKDYYKTSDIGR
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NU3M_PORPU
Sequence: MNVLYNEYSAILTFFAISFSISTLILALSYFLNPQPSDQEKVSAYECGFNPFDDARATFDVRFYLVAILFLIFDLEISFLFPWSLVLGQLSIFGFWSMIVFLIILTLGFIYEWKKGALEWE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TUSA_ALISL
Sequence: MTINFDNATLILEAEGLRCPEPVMMVRKTIRQMADGDTLLIKADDPSTTRDIPSFCRFMDHELIAEDTETLPFRFLIRKGLSA
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_METPP
Sequence: MAKLTKRQKALEGKVDSLKLYAIDDAFKIVRDCATAKFDESIDVSVQLGIDAKKSDQVVRGAVVLPNGTGKTKRVAVFAQGAKAEEAKAAGADVVGMEDLAEQVKAGNLNFDVVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHTTLGRRSFDGDKLKGNLQALIEALNKAKPATSKGIYLRKVAVSSTMGVGVRVDVASINAAAQG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YBJ5_CANAW
Sequence: MFRSLVRKTTPLLAFGVGIAAFPKDWRKGQFGDKKLLVINDSVLEQIRSTDRYKQLVNDPNLKHYNSSHAFPDQHHKNYVNTGLLFGPDLMEIDPIVFLDEKNGELTSFYHLGDKLISQDGQIHNGIVSTILDEGLCSAGFPLLPSKKGVTASLSIDFKNQAPPQSTVVLHAKVKEAKGRKVVIEGYLETLPLNKSETPLLIAESKCVLVEPKWFKYFAWLQV
What are the official names of this protein?
Uncharacterized protein CAWG_04269, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KCTD1_HUMAN
Sequence: MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELRRTPRVPSVIRIKQEPLD
What is the function of this protein?
May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD1, Potassium channel tetramerization domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBA_MICDP
Sequence: MTTTLQQRSRASVWDRFCEWITSTENRIYIGWFGVLMIPTLLAATACFVIAFIAAPPVDIDGIREPVAGSLIYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLLGCACYLGRQWELSYRLGMRPWICVAYSAPLASATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILLHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGVSTMAFNLNGFNFNQSVIDSQGRVIATWADVINRANLGMEVMHERNAHNFPLDLAAGEVAPVALTAPAING
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: VM1B_BOTLC
Sequence: TLTSFGEWR
What is the function of this protein?
Snake venom zinc metalloprotease that has fibrino(geno)lytic activities.  Hydrolyzes the alpha-chain (FGA) and more slowly the beta-chain of fibrinogen (FGB), without affecting the gamma-chain.  Preferentially hydrolyzes the beta-chain (FGB) of fibrin.  In vivo, shows a low edema-inducing effect.  This action may be attributed to degradation of proteins in the cell membrane and consequent release of inflammatory mediators and leukocyte infiltrate.
What are the official names of this protein?
Snake venom metalloproteinase BleucMP, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FPG_BACSU
Sequence: MPELPEVETVRRTLTGLVKGKTIKSVEIRWPNIIKRPAEPEEFARKLAGETIQSIGRRGKFLLFHLDHYVMVSHLRMEGKYGLHQAEEPDDKHVHVIFTMTDGTQLRYRDVRKFGTMHLFKPGEEAGELPLSQLGPEPDAEEFTSAYLKDRLAKTNRAVKTALLDQKTVVGLGNIYVDEALFRAGVHPETKANQLSDKTIKTLHAEIKNTLQEAIDAGGSTVRSYINSQGEIGMFQLQHFVYGKKDEPCKNCGTMISKIVVGGRGTHFCAKCQTKK
What is the function of this protein?
Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool.  8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity).  Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 8-oxo-dGTP.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RS2_SALRD
Sequence: MADETTTDTPDVQDEDAPDEDAPQTPDDTASDSTGEAAAADTDADAPDENAPDEDAPDAAPQDKDDGDDAPEESSSEEETSHRVTIEELLKAGAHFGHLTSRWNPRMEKYIFMERNNIHIIDLMQSQVLLDEAAEAAKRFARRGKKILFAGTKKQAEDIVREHAEECGMPHMVDRWLGGTMTNFQTIRKSIRRMEEIERMDRDGTLDKLKKKEKLMRLREHEKLEETLGGIRDMANLPSAIYIVDVQREDIAVSEANNLGIPIIAMVDTNGNPKNIDYPIPVNDDALSSIELVTSTLTDAVQEGLQERRMKKEEKKKAAA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: URE3_PSEPW
Sequence: MELTPREKDKLLLFTAALLAERRLARGLKLNYPEAVALISAAVLEGARDGRTVAELMSLGREVIGREQVMDGVPEMLHDVQVEATFPDGTKLVTVHDPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_STAAB
Sequence: MDFVNNDTRQIAKNLLGVKVIYQDTTQTYTGYIVETEAYLGLNDRAAHGYGGKITPKVTSLYKRGGTIYAHVMHTHLLINFVTKSEGIPEGVLIRAIEPEDGLSAMFRNRGKKGYEVTNGPGKWTKAFNIPRAIDGATLNDCRLSIDTKNRKYPKDIIASPRIGIPNKGDWTHKSLRYTVKGNPFVSRMRKSDCMFPEDTWK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: LAFX_LACJO
Sequence: MKLNDKELSKIVGGNRWGDTVLSAASGAGTGIKACKSFGPWGMAICGVGGAAIGGYFGYTHN
What is the function of this protein?
Heat stable bacteriocin active against Enterococcus faecalis and other Lactobacilli.
What are the official names of this protein?
Bacteriocin lactacin-F subunit LafX.
What is the protein family that this protein belongs to?
Belongs to the bacteriocin class IIB family.
Protein: APT_STAAT
Sequence: MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BRAHW
Sequence: MVTVKSVFCGEELILETGLLAKQAHGSVTLRLGNTTILATVVAAKEPNLESDFFPLTVNYNEKYYAGGKIPGGFFKREAKPRDKEILISRIIDRPLRPLFPEGFRNEVQIIPTVLSVDTDMPTDALALIASSAALTISWIPFGGPVAAVRIGYKNGEYIINPKNSELSTSELDIIVAGSKDAILMIEGEAKEVSEEVFIGAIELAHKEMQKYIDMQNEMASLCGTQKIEQELFEFDADLVKMVTEYGRDKIESANYNPDKTKRNESMDNAFNEIEEYIKTKVEDEKLISQVKGICHSIEEEIVREAIVEKCMRPDGRALDEIRPITTMTNLIPRVHGSALFTRGQTQCLSIVTLGSEKDAQLMDDIYGKENKTFMLHYNFPPFSVGEVGRYGAPGRREIGHGNLAERSFNAVLPPKDKFPYTIRVVAEILESNGSSSMATICASTMSLLSAGVPLNASVAGIAMGLATYKDGYKILTDIQGVEDHLGDMDFKVAGTRKGITAFQLDIKLTGISAQILKEALEQAKKARYFILDKIDATIANAGEISDFAPKYKTMDVNPEKIRVLIGPGGKNIKAIIEETGSDVEIQDSGVVNIFAPDTPTLDKTIKLINSYVKDPEVGEVYDGIVKDIKDFGAFVEILPGVEGLCHISELAYKHVMNVEEVLKIGDEVKVKILDVKGGKYSLSRKALLEKPADYVEEEYNKKEKKHGKKRF
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_LACP3
Sequence: MMVIVLDNSNIRVVVGMSGGVDSSVTALLLKQQGYDVVGVFMKNWDDTDENGVCTATTDYEDVAKVASEIGIPYYSINFEKEYWDRVFQYFLDEYKAGRTPNPDVMCNKEIKFKAFLDYADQLNADYIAMGHYAQVKTDENGIVHMLRGADGNKDQTYFLSQLSQDQLKKSLFPIGHLQKPEVRKIAEAAGLATAKKKDSTGICFIGERNFKQFLSTYLPAQPGKMMTVDGVEMGTHDGLMYYTIGQRQGLGIGGNSDNSEPWFVVGKDLDKNILYVGQGFDNPALMATSLSASNLNWTTGQAPAEGTHMTAKFRYRQRDTGVTLHYHDDGTATVDFDVPVRAITPGQAVVFYDGDECLGGGTIDAAYAHTNELQYV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVA_STAAW
Sequence: MTVKTTVSTKDIDEAFLRLKDIVKETPLQLDHYLSQKYDCKVYLKREDLQWVRSFKLRGAYNAISVLSDEAKSKGITCASAGNHAQGVAYTAKKLNLNAVIFMPVTTPLQKVNQVKFFGNSNVEVVLTGDTFDHCLAEALTYTSEHQMNFIDPFNNVHTISGQGTLAKEMLEQSKTDNVNFDYLFAAIGGGGLISGISTYFKTYSPTTKIIGVEPSGASSMYESVVVNNQVVTLPNIDKFVDGASVARVGDITFEIAKENVDDYVQVDEGAVCSTILDMYSKQAIVAEPAGALSVSALENYKDHIKGKTVVCVISGGNNDINRMKEIEERSLLYEEMKHYFILNFPQRPGALREFVNDVLGPQDDITKFEYLKKSSQNTGTVIIGIQLKDHDDLIQLKQRVNHFDPSNIYINENKMLYSLLI
What is the function of this protein?
Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction.  The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate).  Both intermediates are unstable and short-lived.  The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia.  In the low water environment of the cell, the second step is accelerated by RidA (By similarity).
What are the official names of this protein?
L-threonine dehydratase biosynthetic IlvA, Threonine deaminase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: RL18_HELHP
Sequence: MTDKVLKRKQLLKVKRKLRTRGKIFGRADKPRVSVFKSNKYFYAQAINDELGVTLASVDGKKLGLGNNKENAKQIANEFATSLKKAKITEVVFDRNGYLYHGVVAAFADTLRENGIKL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y2927_SALTO
Sequence: MIILIHTSKAMRPAPQGGATLTVPALRDRAEELATYLKTLSVEQFAAAMELSPELADRTHGLFADWGTEPERQSPAIDSFAGDIYSGLRACDLTPADRAYAEGRLRILSGLYGILRPEDGIQPYRLEMGYRLPDPPYANLYQFWGDAVARCLPRTGVIVDLAAVEYNRIVTRFLSRDRFVSPRFLTINPKTGEPRFVVVHAKIARGAFARWLLAARVEDPADIVDFAEIGYRYEPALSKPRQPAFVCQEFGGKGLSVRRHDLG
What are the official names of this protein?
UPF0246 protein Strop_2927.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: NRDR_PROMM
Sequence: MQCPSCQNTDSRVLESRAADAGRSVRRRRECLHCDFRFTTYERVETVPITVLKRNGNRETFNRSKILNGLTLACQKTGLEQDRLESMVNELELQLQQRSGREVNSAEIGEMVLDQLSEMSEVAYVRFASVYRDFRGVNDFVAALEGIHANKEQLAAVR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RUVB_SYNY3
Sequence: MAIKRSGNNNLSPNVKSDLLSPEVIPQERSTSPELEQQEASLRPQRLADYIGQRDLKEVLRIAIQAAQGRQEAIDHLLLYGPPGLGKTTLALILAEEMQVRCKITAAPALERPRDITGLLLALQPGDILFIDEIHRLNRLTEELLYPAMEDFRLDITMGKGQSAKVRSLKLAHFTLVGATTKVGSLTSPLRDRFGLIQRLRFYEVDELQQIILRTAGILSVSISPTGAEAIAMRARGTPRIANRLLKRVRDYAQVKQQPEIDPALASEALDLYQVDKRGLDWTDRLVLQTLIEQFQGGPTGLEAIAAATGEDAKTIEEVYEPYLLQIGYLARTSRGRIATTAAYEHLGLTPPTPLLPWKES
What is the function of this protein?
Participates in UV-tolerance of Synechocystis PCC 6803.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TRUD_PSEFS
Sequence: MNDLELLGPRAYGEALGSAVLKATAEDFQVDEVLDIPLTGEGEHLWLWVEKRGLNTEEAARRIAKAAGVPLRTVSYAGLKDRQALTRQWFSVQLPGKADPDMSAAENDTLRILKTGRHKRKLQRGAHSANGFTLRLTQLVGDTAAIDARLQLIAQHGIPNYFGTQRFGHNGGNVVDAREWAVRKALPEQRNARSRLLSTARSYLFNKVLAARVAEGSWQRAQVGDLLAFTDSRSFFPAGEAECSDPRLAILDLHPTGPQWGEGDSPASGATFELEQAVAAGEADLRDWLVNAGMSQERRILRLPIGGLTWHYPSLDILQLEFVLPAGCFATVLVRELVDLVPVGQTDNPCVF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: Y2307_MYCTU
Sequence: MSLKRCRALPVVAIVALVASGVIMFIWSQQRRLIYFPSAGPVPSASSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRAELAVALHGLGLSVLLFDYRGYGGNPGRPSEQGLAADARAAQEWLSGQSDVDPARIAYFGESLGAAVAVGLAVQRPPAALVLRSPFTSLAEVGAVHYPWLPLRRLLLDHYPSIERIASVHAPVLVIAGGSDDIVPATLSERLVAAAAEPKRYVVVPGVGHNDPELLDGRVMLDAIRRFLTETAVLGQ
What are the official names of this protein?
Uncharacterized protein Rv2307c.
What is the protein family that this protein belongs to?
To S.pombe bem46 and yeast YNL320w.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YFBV_SALA4
Sequence: MSTPDNRSVNFFSLFRRGQHYAKTWPMEKRLAPVFVENRVIRMTRYAIRFMPPVAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPSILNWFYEVRGKLQEAGQALAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSRP_VIBVY
Sequence: MQTEKQSRDVFYVSDGTAITCETLGHVVLGQFPFVANEKTFPFVESEEKLTELIKHIEISFQTNGIKPLVFFSLVLPDLKARLMESPAYCYDVLESIVQRVKDDIQMEPTPKLQRSRSVGKDTDTYFDRIAAIEYTLAHDDGISLKGLELADIILLGVSRSGKTPTSLYMAMQFGLRVVNYPYIDDDIKGLKLLPEFEIHRHKLFGLTIDPERLTEIRENRLAGSDYASTEQCQHELANVEALFRREAIPYINTTSLSVEEISTRVLEKTGLKRRLF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: IF2P_THEON
Sequence: MKRIRQPIIAVLGHVDHGKTTLLDRIRRTNVAGKEAGGITQHIGATEVPIETVKNLAGPLIKLWKGEIKLPGLLFIDTPGHEAFTSLRARGGSLADLAVLVVDINEGFQPQTIESIEILRKNRTPFIVAANKIDRIKGWKIEKDEPFLVNIKKQDQRAQQELETKLWELIGKFYEMGFQANRFDRVQNFTRELAIVPISAKYGIGVPELLVLIAGLSQKYLEEKLKIEVEGPARGTILEVREEIGLGTTIDVIIYDGTLHKDDTIVVGGKDKAIVTKIRALLKPKPLDEIRDPRFRFDQVDEVTAAAGVKIAAPGLEEALAGSPVIAARSEEEVEKAKQEILSQIQSVVISTGKVGVIVKADTLGSLEALSKELQEKNIPIRKADVGNISKTDVMEALSVKDEDPKYGVVLGFNVKVNEDAEEVAKARGVPIFTGNIIYKLIEDYEAWVKGEEEKKKRELLSKVTFPGVIRLYPDERYVFRRSHPAIVGIEVVEGRIRPGVTLIKQNGQKVGVIKSIKNRNDFVQEAKKGEAVAIAIEGAIVGRHIHPGETLYVDLSKNDVIILAKQLKNELDETDIKALKMTAKVKAQQDPFWKAV
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.