PharMolix/UniProtQA huggingface dataset:
Protein: METN1_BACAN
Sequence: MIELKNVSKVFTTKKGNVEALKSTSLQVKKGEVFGIIGYSGAGKSTLIRCVNLLEKPTTGNIIVNEQDLTTLSTKELAKARQKIGMIFQGFNLLKTVTVYENIALPLRLAGVPKLEIEKRVEKYLRIVDLFNRKDAYPSELSGGQKQRVAIARALSHEPEVLLSDEATSALDPETTDSILDLLLKINEEIGITILLITHEMNVIQRICDRVAVMEHGAVVESGTVKDIFTNPQHVTTKKFVNSAFAAKIPAEVQKELQRTGEIVTLSFIGNSSGEPALAVATKRFQVYPNILSGNITQLKHEAYGKLVIHMQGEQNEINHALSFLQEQGIIVEGGRTDYGKQVLFG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNZ_LACDA
Sequence: MELEFLGTCSGQPSKLRNVSSLALKLLDELNEIWLFDCGEATQHQILRTNIRLRKITKIFISHNHGDHIFGLPGLLSTRSFQGDVGPLTIYGPAGIEQFVKTSLRISKTKISYPIKFVTLEEGGKIVSERGFEVYTEKLDHRIDSWGFRMVEADKAGELLMDKLAEFKVPNGPLLGKLKRGEQVELADGTVLNGKDFLGPAKKGRVVTVIYDTRSTPSIRRLADHADVLVHEATFDASEGKLARDYYHSTCTQAAETASACHVGHLYLTHVSARYVGSLASQMVKQAREIFPATTLAKDLDKFVVPMKG
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: CLPP_METC4
Sequence: MRDPVDYFHNSLVPMVVEQSSRGERAFDIYSRLLRERIIFLTGPVEDQGASLIVAQLLFLEAENPKKEISFYINSPGGVVTSGLSIYDTMQFIRCPVTTLCVGQAASMGSLLLAAGEAGHRFALPNARIMVHQPSGGFQGQATDILIHAREIEALKKRLNEIYVKHTGREYETIHQALERDNFMTADAAKEFGLIDDILHKRPEPAAA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AD4F1_MOUSE
Sequence: MLYLVGFLLATVCLLVLGVNVWVLIDHFLTIDVPPSIPHPVKFRILHFCFHLTTTWGHILEKMNICSMPQFFCFLQDSLSSKENHGVFVKDLRFGTIPVRLFRPKAASSKPRRGILFFHGGGAMIGSLDSHHNLCTFLARETDSVLVSVGYRKLPYYHHPSLYHDCINASIHFLKSLKAYGIDPSRVVICGESIGGAAAVVVTQTLLSRTDIPKIRAQVLIYPILQAFYFQSPSHLMHKNIPFLTKDFMITCICKYLAIDFSWKDAMLTGACISPSAWKKYEKWLSPDNIPKRFRTTYQPPESPAPFNEAAYLETKHAMNIDISPLVADDKIIAQLPEAFLVSLHWDIIRDDVLLYKKRLEDQGVPVTWHHVEDGFHGCILLFDKKLFSFPCSLNIVNAVVSYIKDL
What are the official names of this protein?
Arylacetamide deacetylase-like 4 family member 1, AADACL4 family member 1.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MUTL_CHLMU
Sequence: MSLSSSRIRLLDSATVNQIAAGEVIENAASVVKELIENALDAGADEISIETLGGGKGQIVVRDNGIGMDADEVAVAIQRHATSKISHFADIFSLASFGFRGEALPAIASISKMEIHTAKVNGLGSKTLIEKGEPVCCEACPRQPGTTISVNSLFYNVPMRQSFQKSPQMDRLAIRRLLENSILSTEGIKWTWISERRQELNIAKNQGFTERVALVMGEAFVNEAFLIDKRQNELHLTGFLGSPSMHRSTRQGQRLFINNRAVESSFISRKVAEAYAWMLPAQRYPAFVLKLSVPPMWCDFNVHPQKTEVRLLQEGQIGALLVEAISEVLLHRSPSLEEKMVEPTMESPLIENGGLEIPSIRPVAISTPLSCPNFLQQSFVETEANRALCKEQENLALPIIERVRFLASLGKVILVEDSEGVHALFVQAARKHLFYISLLSKRSDSLLACQMFLVPPTVQMTKLEADFLQTRLESLAAQGIELCRISPDSFAIESAPPFIQEEELKEWIISLAHEGAFQVNESFEQLVENTVQKLAFSKNTRAFDHSWINVLWQIGKPEKAFDGETIRRLVLEEDFM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: FIXP_BRASO
Sequence: MADHSEVDSVSGTATTGHAWDGIKELNTPLPRWWVITFYITIVWAIGYWIVYPAWPTITSNTKGLFGYSSRADVAVELANLEKIRGDKMAALATASLADIEKDPQMLALARAKGKTVFGDNCAACHGTGAAGAKGFPNLNDDDWLWGGSLEQIQQTLLYGVRSGHPKTREGQMLAFGKDGTLKPAEIITVANYVRSLSGLPTRQGYDAAAGAKIFAENCVACHGDNAKGNPEVGAPNLTDKIWLYGSDEATLIETITNGRAGVMPAWEGRLDPTTIKAMAVYVHSLGGGK
What is the function of this protein?
C-type cytochrome.  Part of the cbb3-type cytochrome c oxidase complex.  FixP subunit is required for transferring electrons from donor cytochrome c via its heme groups to FixO subunit.  From there, electrons are shuttled to the catalytic binuclear center of FixN subunit where oxygen reduction takes place.  The complex also functions as a proton pump (By similarity).
What are the official names of this protein?
Cbb3-type cytochrome c oxidase subunit FixP, Cbb3-Cox subunit FixP, C-type cytochrome FixP, Cyt c(FixP), Cytochrome c oxidase subunit III.
What is the protein family that this protein belongs to?
Belongs to the CcoP / FixP family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: QUEF_HAES1
Sequence: MQYHDQSLQTLKLGKKTEYISTYDRTLLQAVPRKLNRDDLGISTKQPFSFGADIWTAYEISWLNLKGVPQVAIADVEIDYQSENLIESKSFKLYLNSFNQSQFENLQQVEQILQQDLIKCAKGQVKVRLNSLQNYAQQPIATLQGECIDEQDIEIRCYEFDPNLLENCTNKQWVEEKLVSHLLKSNCLITNQPDWGTVQIHYIGNQINREKLLRYLISFRQHNEFHEQCVERIFCDLMKFAQPEKLSVYARYTRRGGLDINPFRSNFEPIPLNQRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBRL_HUMAN
Sequence: MSEHVEPAAPGPGPNGGGGGPAPARGPRTPNLNPNPLINVRDRLFHALFFKMAVTYSRLFPPAFRRLFEFFVLLKALFVLFVLAYIHIVFSRSPINCLEHVRDKWPREGILRVEVRHNSSRAPVFLQFCDSGGRGSFPGLAVEPGSNLDMEDEEEEELTMEMFGNSSIKFELDIEPKVFKPPSSTEALNDSQEFPFPETPTKVWPQDEYIVEYSLEYGFLRLSQATRQRLSIPVMVVTLDPTRDQCFGDRFSRLLLDEFLGYDDILMSSVKGLAENEENKGFLRNVVSGEHYRFVSMWMARTSYLAAFAIMVIFTLSVSMLLRYSHHQIFVFIVDLLQMLEMNMAIAFPAAPLLTVILALVGMEAIMSEFFNDTTTAFYIILIVWLADQYDAICCHTSTSKRHWLRFFYLYHFAFYAYHYRFNGQYSSLALVTSWLFIQHSMIYFFHHYELPAILQQVRIQEMLLQAPPLGPGTPTALPDDMNNNSGAPATAPDSAGQPPALGPVSPGASGSPGPVAAAPSSLVAAAASVAAAAGGDLGWMAETAAIITDASFLSGLSASLLERRPASPLGPAGGLPHAPQDSVPPSDSAASDTTPLGAAVGGPSPASMAPTEAPSEVGS
What is the function of this protein?
May have a role in the ERAD pathway required for clearance of misfolded proteins in the endoplasmic reticulum (ER).  Promotes survival of motor neurons, probably by protecting against ER stress.
What are the official names of this protein?
Membralin, Transmembrane protein 259.
What is the protein family that this protein belongs to?
Belongs to the membralin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CCRM_BRUSI
Sequence: MSLVRLAHELPIEAPRTAWLDSIIKGDCVSALERLPDHSVDVIFADPPYNLQLGGDLHRPDQSMVSAVDDHWDQFESFQAYDAFTRAWLLACRRVLKPNGTIWVIGSYHNIFRVGTQLQDLGFWLLNDIVWRKTNPMPNFRGRRFQNAHETLIWASRDQKGKGYTFNYEAMKAANDDVQMRSDWLFPICTGSERLKDENGDKVHPTQKPEALLARIMMASSKPGDVILDPFFGSGTTGAVAKRLGRHFVGIEREQPYIDAATARINAVEPLGKAELTVMTGKRAEPRVAFTSVMEAGLLRPGTVLCDERRRFAAIVRADGTLTANGEAGSIHRIGARVQGFDACNGWTFWHFEENGVLKPIDALRKIIREQMAAAGA
What is the function of this protein?
A beta subtype methylase that recognizes the double-stranded sequence 5'-GANTC-3' and methylates A-2 on both strands (PubMed:12654995) (By similarity).  CcrM-mediated methylation has important cellular functions.  Contributes to the accurate cell-cycle control of DNA replication and cellular morphology (By similarity).
What are the official names of this protein?
DNA methyltransferase CcrM, M.CcrM, Adenine-specific methyltransferase BabI, Type II methyltransferase M.Bsu23445ORF519P, M.Bsu23445ORF519P.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: T2R41_PANPA
Sequence: MQAALTAFFMLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQLVGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHPTFLWLKWRFPAWVPWLLLGSVLISFIITLLFFWVNYPAYQEFLIRKFSVNMTYKWNTRIETYYFPSLKLVIWSIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFLILYALSFLSLIIDATKFISMQNDFYWPWQIAVYLCISIHPFILIFSNLKLRSVFSQLLLLARGFWVA
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 41, T2R41.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TOLB_PSEFS
Sequence: MRNLLRGMLVVICCMAGIAAADEKNILVTSGSDRATPIAVVPFGWQGGSVLPDDMAQIVSDDLRNSGYYAPIPKGNMISQPNQASEVVFRDWKAVGAQYLMVGNITPAGGRLQIQYTLFNVATEQQVLTGSVSGTAEQLRDMAHYISDQSFEKLTGIKGAFSTRLLYVTAERFSVDNTRYTLQRSDYDGARAVTLLQSREPILSPRFAPDGKRIAYVSFEQRRPRIFVQHIDTGRREQITNFEGLNGAPAWSPDGSRLAFVLSKDGNPDIYVMNMASRQISRVTSGPGINTEPFWGKDGSTIYFTSDRGGKPQVYKANVNGGGAERVTFIGNYNANPKLSADEKTLVMIHRQDGFTNFRVAAQDLQRGTVKILTDTNLDESATVAPNGTMVIYATRQQGRGVLMLVSINGRVRLPLPTAQGEVREPSWSPYLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ROCA_BACCN
Sequence: MVVAYKHEPFTDFSVEANKLAFEEGLKKVESYLGQDYPLIIGGEKITTEDKIVSVNPANKEEVIGSVSKASRELAEKAMQVADETFQTWRKSKPEMRADILFRAAAIVRRRKHEFSAILVKEAGKPWNEADADTAEAIDFMEYYGRQMLKLKDGIPVESRPIEYNRFSYIPLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGVVNFIPGSGSEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVHPGQIWLKRVIAEMGGKDTIVVDKEADLELAAKSIVASAFGFSGQKCSACSRAVIHEEVYDQVLNRAVELTKELTVGNPAEKGTNMGPVNDQAAFDKVMSYVAIGKEEGKIVAGGEGDDSKGWFIQPTIVADVAEDARLMKEEIFGPVVAFCKAKDFDHALAIANNTEYGLTGAVISNNRAHIEKAREDFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLALHMQAKTTSEML
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: MMS5_MAGSA
Sequence: MLSAKGVSLGLGLGLGAWGPVLLGVVGVAGAIALYGYYKNRNAEPAAAEAV
What is the function of this protein?
Might be involved in magnetite crystal growth.
What are the official names of this protein?
Magnetosome protein Mms5.
What is the protein family that this protein belongs to?
Belongs to the magnetosome MamD/Mms5 family.
What are the subcellular locations of this protein?
Magnetosome membrane; Single-pass membrane protein. Note=Tightly associated with magnetite crystals.
Protein: GCSP_PSEFS
Sequence: MTVNLTTANEFIARHIGPRQEDEQHMLASLGFDSLEALSASVIPESIKGTSVLGLEDGLSEAEALAKIKAIAGQNQLFKTYIGQGYYNCHTPSPILRNLLENPAWYTAYTPYQPEISQGRLEALLNFQTLISDLTGLPIANASLLDEATAAAEAMTFCKRLSKNKGSNAFFASIHSHPQTLDVLRTRAEPLGIDVVVGDERELTDVSAFFGALLQYPASNGDVFDYRALTERFHASNALVAVAADLLALTLLTPPGEFGADVAIGSAQRFGVPLGFGGPHAAYFSTKDAFKRDMPGRLVGVSVDRFGKPALRLAMQTREQHIRREKATSNICTAQVLLANIASMYAVYHGPKGLTQIAQRIHQLTAILAKGLTALGQKVEQEHFFDTLTLNTGANTATLHDKARAQRINLRVVDAERLGVSVDETTTQADIETLWAIFADGKALPDFAANVDSTLPAALLRQSPILSHPVFNRYHSETELMRYLRKLADKDLALDRTMIPLGSCTMKLNAASEMIPVTWAEFGALHPFAPAEQSAGYLQLTSDLEAMLCAATGYDAISLQPNAGSQGEYAGLLAIRAYHQSRGEERRDICLIPSSAHGTNPATANMAGMRVVVTACDARGNVDIEDLRAKAIEHRDHLAALMITYPSTHGVFEEGIREICGIIHDNGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVKSHLTPFLPGHAAMERKEGAVCAAPFGSASILPITWMYISMMGGAGLKRASQLAILNANYISRRLEEHYPVLYTGSNGLVAHECILDLRPLKDSSGISVDDVAKRLIDFGFHAPTMSFPVAGTLMIEPTESESKEELDRFCDAMIAIREEIRAVENGTLDKDDNPLKNAPHTAAELVGEWSHPYSREQAVYPVASLIEGKYWPPVGRVDNVFGDRNLVCACPSIESYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: YQHG_ECOLI
Sequence: MKIILLFLAALASFTVHAQPPSQTVEQTVRHIYQNYKSDATAPYFGETGERAITSARIQQALTLNDNLTLPGNIGWLDYDPVCDCQDFGDLVLESVAITQTDADHADAVVRFRIFKDDKEKTTQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLAALASLQKEQPEAFVAELFEHIADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDMQIERQFIYDNPICFGEESLFSRVDEIRVLEKTADSARIHVRFTLTNGNNEEQELVLQRREGKWEIADFIRPNSGSLLKQIEAKTAARLKQ
What are the official names of this protein?
Uncharacterized protein YqhG.
Protein: SYA_SALPA
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPNNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTGENWFALPKERLWVTVYETDDETYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIEAVAKVTGATDLGNKSLRVIADHIRSCAFLVADGVLPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIEVMGSAGEELKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLQGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEVGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVEAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGAGFTFAVDDTQKYGQAIGHIGKLSAGALKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVAQKGSLVSDKVLRFDFSHNEAMKPSEIRQVEDLVNAQIRRNLPIETNIMDLDAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGIRRIEAVTGEGAMATVHAQSDRLNDIAHLLKGDSQNLGDKVRAVLERTRQLEKELQQLKDQAAAQESANLSSKAVDLNGVKLLVSELAGIEPKMLRTMVDDLKNQLVSTVIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVQGWVSAKLQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y174_TREPA
Sequence: MQGQVLKKVLKKYVHIGMCTLFLHAILLFPCVAQAVLCQIFLSALIRNTSRMPHTMCSFPSQVTAIFDICACPCAVRSFYLNGNSLIFTGGGHPFSVYASRFSSLPFLETSSGTVAGAAYSVASFLGFTRITSVGTDFSYTNGKPYARGTYLSKQFEQKILRISPLETQFCNLMFRTPTRQDNTQGGITYSNEILDQYKRNFDQITPGARPWHAADFRAFPYKQFINFFHAQLRSKHAAALLAMLPFITWYKTKRTPQAPIFRILELVLEDVLRYTRYNE
What are the official names of this protein?
Uncharacterized protein TP_0174.
Protein: ATPB_PROMH
Sequence: MATGKIVQVIGAVVDAEFPQDSVPKVYDALEVMNGKEKLVLEVQQQLGGGIVRCIAMGTSDGLSRGLKVEDLGHPIEVPVGKATLGRIMNVLGTPIDMKGEIETEERWSIHREAPTYEELSNSQELLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKFVSLKDTIRGFKGILNGDYDHLPEQAFYMVGTIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MGLA_ECOL6
Sequence: MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDSMRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQSEILRLASLHL
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Galactose/methyl galactoside import ATP-binding protein MglA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL23_VIBPA
Sequence: MITEERILKVLRAPHISEKATMAAEKANTIVFKVAKDATKKEIKAAVEKLFEVEVKSVNTLITKGKTKRQGLRQGRRSDVKKAYVTLKEGQDLDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RNF13_HUMAN
Sequence: MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates cell proliferation (PubMed:18794910, PubMed:23378536, PubMed:30595371).  Involved in apoptosis regulation (PubMed:23378536, PubMed:30595371).  Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (PubMed:23378536, PubMed:30595371).  Also involved in protein trafficking and localization (PubMed:24387786).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF13, RING finger protein 13.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Nucleus inner membrane; Single-pass type I membrane protein. Note=Under certain conditions, relocalizes to recycling endosomes and to the inner nuclear membrane.
Protein: GRP1_PSIGU
Sequence: RESPSSRMECYEQAERYGYGGYGGGRYGGGYGSGRGQPVGQGVERSHDDNRNQPR
What is the function of this protein?
Has antibacterial activity against the Gram-negative bacteria Klebsiella sp. , Proteus sp. , E. coli ATCC 8739 (MIC=72 ug/ml) and K. pneumoniae (MIC=32 ug/ml).  Has no activity against the Gram-negative bacterium S. typhimurium or the Gram-positive bacterium S. aureus.  Does not have antifungal activity against the human and plant pathogenic fungi F. oxysporum, A. fumigatus and R. solani.
What are the official names of this protein?
Glycine-rich antimicrobial peptide Pg-AMP.
Protein: PSBZ_STAPU
Sequence: MTTLFQLSVFALIILSFLLVIGVPVVLASPDGWSTRKNTVFSGASLWIGLVFLVGILNSFIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: THII_PSEU2
Sequence: MKLIVKVFPEITIKSPPVRKKFIRQLGKNIRTVLRELDADIVVGGVWDNLEVETRLTDPKVLQGIRERLSCMPGIANFLQVAEYPLGDLDDVVAKCELHYADLLPGKMFSVRCKRAGRHDFSSMDVEKYVGSKLRMQCGAAGIELKKPDLVVRMEIRDQRLFVVHDQHQGMGGYPLGALEQTLVLMSGGFDSTVAAYQIMRRGLMAHFCFFNLGGRAHELGVMEVAHFIWKKYGSSQRVLFVSVPFEEVLGEILQKVDNSHMGVVLKRMMLRAASAVADRLEIDVLVTGEAISQVASQTLPNLSLIDAATDKLVLRPLVATHKQDIVDLATEIGTADFARHMPEYCGVISVNPKTNAKRNRVEYEEKQFDMAILEQALERAKLVSIDRVIDDLSRNVDIEEVSQALAGQVILDIRHPDAQEDQPLQVPGVEIQTLPFYALNSRFKALDDTRQYLLYCDKGVMSRLHAHHLLSEGHANVRVYRPS
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP4_ROTH3
Sequence: MEKLTDLNYTLSVITLMNDTLHTIMEDPGMAYFPYIASVLTVLFTLHKASIPTMKIALRTSRCSYKVIKYCIVSIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRQLEMIDKLTTREIEQVELLKRIHDMLIIKPVDKIDMSQEFNQRQFKTLNEWAEGENPYEPKEVTASL
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.