PharMolix/UniProtQA huggingface dataset:
Protein: ERV41_YEAST
Sequence: MAGLKTFDAFPKTEEQYKKKSTKGGLTSLLTYLFLLFIAWTEFGEYFGGYIDQQYVVDSQVRDTVQINMDIYVNTKCDWLQINVRDQTMDRKLVLEELQLEEMPFFIPYDTKVNDINEIITPELDEILGEAIPAEFREKLDTRSFFDESDPNKAHLPEFNGCHVFGSIPVNRVSGELQITAKSLGYVASRKAPLEELKFNHVINEFSFGDFYPYIDNPLDNTAQFNQDEPLTTYVYYTSVVPTLFKKLGAEVDTNQYSVNDYRYLYKDVAAKGDKMPGIFFKYNFEPLSIVVSDVRLSFIQFLVRLVAICSFLVYCASWIFTLLDMALITIMGPKWSLRYQPDDKTKGILDR
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi (PubMed:11157978, PubMed:12426381).  The C-terminal Ile-Leu motif is required for exit from the endoplasmic reticulum (PubMed:12426381).  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (PubMed:12426381).
What are the official names of this protein?
ER-derived vesicles protein ERV41.
What is the protein family that this protein belongs to?
Belongs to the ERGIC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Recycles between endoplasmic reticulum and Golgi. Resides in the endoplasmic and Golgi compartments, and then packaged into endoplasmic reticulum derived vesicles.
Protein: COX3_ARTSF
Sequence: MNQLNHPYHLVNISPWPLATGMGAFAMTSGLVKWFHSFDSMLFFTGINNNHICFDQWWRDVSREATFQGMHSTKVGFGLRWGMILFIISEVFFFVSFFWGFFHSSLSPNIEVGALWPPSEVESFLSALLNTSILLASGVTVTWAHHALMENNFDQCLQGLLFTVLLGLYFSFLQGLEYMEASFTIADSIYGSTFFLATGFHGLHVLIGTIFLMICILRHAKCYFSQHHFGFEAAAWYWHFVDVVWLFLYLSIYWWGE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: H10_MOUSE
Sequence: MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKGDEPKRSVAFKKTKKEVKKVATPKKAAKPKKAASKAPSKKPKATPVKKAKKKPAATPKKAKKPKVVKVKPVKASKPKKAKTVKPKAKSSAKRASKKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.  The histones H1. 0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
What are the official names of this protein?
Histone H1.0, Histone H1', Histone H1(0), MyD196.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AP1B1_RAT
Sequence: MTDSKYFTTTKKGEIFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANRVAALSEIAESHPSSNLLDLKAQSINKLLTALNECTEWAQIFILDCLGNYMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYATLLKKLAPPLVTLLSAEPEPQYVPLRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLDGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYHKPPNAFVEGGRGVVHKSLPPRTASSESTESPEAAPAGAPASDQPDVIPAQGDLLGDLLNLDLGPPVSGPPLAASSVQMGAVDLLGGGLDSLMGDEPEGIGDSNFGAPPASVAAAAPARLGAPVSSGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPAAPLQVHAPLSPNQTVEISLPLNTVGSVMKMEPLNNLQVAVKNNIDVFYFSTLYPLHVLFVEDGKMDRQMFLATWKDIPNENEAQFQIRDCPLNTEAASSKLQSSNIFTVAKRTVEGQDMLYQSLKLTNGIWVLAELRIQPGNPSFTLSLKCRAPEVSQHDIQAYETILKN
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes.  The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
What are the official names of this protein?
AP-1 complex subunit beta-1, Adaptor protein complex AP-1 subunit beta-1, Adaptor-related protein complex 1 subunit beta-1, Beta-1-adaptin, Beta-adaptin 1, Clathrin assembly protein complex 1 beta large chain, Golgi adaptor HA1/AP1 adaptin beta subunit.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, clathrin- coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: RUTC_METC4
Sequence: MPKTVVIPPGTGKPLAPYVPGTLADGVLYVSGTLPLDAEANVVHEGDAGAQTRHVLETIKGVVEAAGGSMDDVTFNHIFLKDWADYGAINAVYATYFPGEKPARYCIQCGLVKPTALVEIASVAHIGKPA
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: HIS2_SACS2
Sequence: MSNEIVDELYKIILDRIEKRPTGSYTAEIVNKGKPYVARKVGEESVETIVASLAENKERFISEVADLIYHLLVLMALEGVTPEDIYRELERRRK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_ACIF5
Sequence: MKFIDEVRIHVASGNGGHGAVSFRREKFIPFGGPDGGDGGRGGSVYLVAQASLNTLIDFRYQRRYRAENGHGGAGRQMTGRAGHDLEIKVPVGTLVYDDDTHELLGDLRFEGERLLIARSGRGGHGNLFYKSSTNRAPRQFEKGGAGEERDLRLELRLLADVGLLGLPNAGKSTLIRAVSAARPKVADYPFTTLYPNLGVVRVAAHESFVLADIPGLIPGASEGAGLGTRFLKHLSRTRLLLHLVDMAPVDGSDPAMNIRALEMELAAYSPTLAARPRWLVVNKSDLLPGEEAEARFQQICTALQWESPAFLISAASGAGCEALVYAIWQALPDLPPAADPTQTEDWGDESDAGERLENWEGDDLDADWEEEQV
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_YERPB
Sequence: MISVRRGLSQLWYWGKRGVIGIIALWMAGILIFAFLPVPFSMVMIERQLGAWLTGDFAYVAHSDWVPMDEISPYMALAVMAAEDQKFPDHWGFDVGAIESALSHNQRNQKRIRGASTLSQQTAKNVFLWDGRSWVRKGLEVGLTAGIELIWTKRRILTVYLNIAEFGNGIFGVEAAARHFFNKPASKLSASEAALLAAVLPNPLRFKVNAPSGYVISRQQWILRQMHQLGGKTFLQENTLD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NMUR2_MOUSE
Sequence: MGKLENASWIHDSLMKYLNSTEEYLAYLCGPKRSDLSLPVSVVYALIFVVGVIGNLLVCLVIARHQTLKTPTNYYLFSLAVSDLLVLLLGMPLEVYELWHNYPFLFGPVGCYFKTALFETVCFASILSVTTVSIERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQQFPNGSSVPGSATCTVTKPIWVYNFIIQATSFLFYILPMTLISVLYYLMGLRLKRDESLEADKVTVNIHRPSRKSVTKMLFVLVLVFAICWTPFHVDRLFFSFVDEWTESLAAVFNLIHVVSGVFFYLSSAVNPIIYNLLSRRFRAAFRNVVSPSCKWCHPQHRPQGPPAQKVIFLTECHLVELTEDAGPQFPCQSSIHNTQLTTVPCVEEVP
What is the function of this protein?
Receptor for the neuromedin-U and neuromedin-S neuropeptides.
What are the official names of this protein?
Neuromedin-U receptor 2, NMU-R2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RF3_CUPPJ
Sequence: MSSLVSEIARRRTFAIISHPDAGKTTLTEKLLWFGGAIQVAGEVRARKADRHATSDWMELEKQRGISVTSSVMQFPYRREAADGKAEENIVNLLDTPGHEDFSEDTYRTLTAVDSAVMVIDSVNGVEAQTIKLLNVCRLRATPILTFINKLDREGRSPIELLDEIEDVLQIQCAPMTWPIGMGKAFRGVYHLIDDKVQLFDPHGDKGTAAILDGLDNPELDRILGSQADELRLEIELVRGASHTFDKEAFLAGKQTPVYFGSAINNFGVQSLLDALCQLSPPPLARNTESRVVEPQEGKFTGFVFKIQANMDPRHRDRIAFVRVCSGRFERGMKLLHVSQAKTVAINNAITFMAQDRNTTEEAYAGDIIGVPNHGTIRLGDVFTEGEPLKFTGIPSFAPEFFRRARLNNPLKVKQLQKGLQQLAEEGATQMFRPLASNELVLGAVGILQFDVVAHRLEHEYGVDAIFESHECATARWLKGAPAEIEKLIAKAGHNVALDGAGDHVYLAPSMVNLRLTQEKFPDVQFLETREIV
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MELT_DROME
Sequence: MHELFNKVLAKRDLSRAGDLFSVPDADIVDDITEVLSEISPIISHADYVKNNNDQSVVEICVTRVLSCIRETKTAERYCAALVDLLRTCLLWNLQPSGTTKEEPPHAKIAADIISSIFLNYDKKELMKIALPVAVQFLPKGNRELSRNLASYLSLAAIDHAGLLSPHTESVMESILSGNYGLLRVLSQVYEVAPEAVTPHAPLLMPLLPQCDPQERMAVFQLYLLIVQKSPEVLESCVPQLCGSLLDSDTSSITMQILLKLSQHSPSLLVDHFEQLRLAAKTNPGTIPLCAQIMTTAGIGSKETAQQALDFVLEHLPTQALLQQEATRLCSAYPVLFTDKVLACVRQKNAALSSQQDVGNGLANKTSGGVTIVSLNSSSPSPPLKPVPVGAPAINTTIVQPASVVSATPTPPPSSASAPIASSTPVSAATPTPQHAGYTRRVKLGDSRSTGRLHPASNTHRSVTRLNVASGSVGGLHKSMTRLSNSQINQQPGGSSNGNVVVQSGATPKTPTGLSNPPVTPVPPLSNNVVITGHNRHGIPVTSGGVTVTTSPSKVRPHSQGPSTLLNSSTVLMKYSTDALNQSVGSISIPQSAAVATLPSTQTQNAVSVHHASPALPQSASNGHAKSVMKLPVNGNSEVIVSGPTTNVAPRRSDNTSRTLLNANSVMDQRMSTFEPYQIMRDPVQQFCEKNFNSIKSYMDEVSQHLPPPTRCSIEVSNEFAERRTKKVAKLHFACQIRGPHCLYSKTCFTMRTRNPKTWIHMMFLDFQVRHFVKEKCVLSTRESGISNLKNIWQILKCENRSFTELVTSQFPQVKDREILVNELRHSGFLDVFEVSKTDKSNPNCNELEYQWGCFLCNHPDKAVGFLNGSNQPMIEGQLKEKKGKWRLFRRWRTRYFTLSGAHLSCKGSSGGESIDVNQIRSVKVSRGARNIPKAFEIFTADQTLILKPKDGKNAEEWVQCLSIVVAHSQARDNPTAKTNSLPARSIGSSKPSF
What is the function of this protein?
Participates in fat metabolism regulation by recruiting FOXO and the TSC1-TSC2 complex to the cell membrane, which positively regulates TOR activity and negatively regulates the expression of FOXO target genes.  Involved in R8 photoreceptor subtype specification.  During early embryonic development, may be required for ectodermal patterning.
What are the official names of this protein?
Protein melted.
What is the protein family that this protein belongs to?
Belongs to the MELT/VEPH family.
Protein: KBTB1_VACCW
Sequence: MNNSSELIAVINGFRNSGRFCDISIVINDERINAHKLILSGASEYFSILFSNNFIDSNEYEVNLSHLDYQSVNDLIDYIYGIPLSLTNDNVKYILSTADFLQIGSAITECENYILKNLCSKNCIDFYIYADKYNNKKIESASFNTILQNILRLINDENFKYLTEESMIKILSDDMLNIKNEDFAPLILIKWLESTQQSCTVELLRCLRISLLSPQVIKSLYSHQLVSSIYECITFLNNIAFLDESFPRYHSIELISIGISNSHDKISINCYNHKKNTWEMISSRRYRCSFAVAVLDNIIYMMGGYDQSPYRSSKVIAYNTCTNSWIYDIPELKYPRSNCGGLADDEYIYCIGGIRDQDSSLTSSIDKWKPSKPYWQKYAKMREPKCDMGVAMLNGLIYVMGGIVKGDTCTDALESLSEDGWMKHQRLPIKMSNMSTIVHDGKIYISGGYNNSSVVNVISNLVLSYNPIYDEWTKLSSLNIPRINPALWSAHNKLYVGGGISDDVRTNTSETYDKEKDCWTLDNGHVLPRNYIMYKCEPIKHKYPLEKTQYTNDFLKYLESFIGS
What is the function of this protein?
Probable substrate-specific adapter of CUL3-containing E3 ubiquitin-protein ligases which mediate the ubiquitination and subsequent proteasomal degradation of host target proteins.
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein A55.
What is the protein family that this protein belongs to?
Belongs to the poxviruses A55 protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: CASP4_SOYBN
Sequence: MAASKDRENFVYIAKLAEQAERYEEMVESMKNVANLDVELTVEERKKGVAILDFILRLGAITSALGAAATMATSDETLPFFTQFFQFEASYDSFSTFQFFVIAMAFVGGYLVLSLPFSIVTIIRPHAAGPRLFLIILDTVFLTLATSSAAAATAIVYLAHNGNQDSNWLAICNQFGDFCQEISGAVVASFVAVVLFVLLIVMCAVALRNH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 4, GmCASP4.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: YBAB_ECO7I
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YIDD_CHLCV
Sequence: MSFKLFIKNLPTNLCCGLIHIYRWTISPLLGSPCRFFPTCSQYALQALKHHGCIKGLGLTIKRIGKCGPWHPGGVDLVPMTTLEEALDISPAVDDDESCDLHA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LRGA_STAAW
Sequence: MKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPGSVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR14_ATRBE
Sequence: MAKKSLIQREKKRQKLEQKYHSIRRSSKKEISKVPSLSDKWEIYGKLQSLPRNSAPTRLHRRCFLTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL29_METKA
Sequence: MGKFKLRPDEIREMTPEERREKLKELKAELLREMTSKSISGVPDNPGRVKEIKKNIARILTTEREEELRKIRETEKG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SYW_CLOTE
Sequence: MGGINMEDNKKTIFSGIQPSGNLTIGNYFGALKNWVKLQDEYNCFYCIVDLHAITVRQVPQELRKRTLEVLAVYIASGLDPEKNTLFIQSHVPAHTEAAWLLNCFTYLGELNRMTQFKDKSQNAGESISAGLLNYPVLMAADILLYNADLVPVGNDQKQHLELTRDIATRFNNLYSPTFKVPEPYIGKTGARIMDLQEPKKKMSKSAENKNGYILIMDPPNIIQNKINRAVTDNEGIVRYSDEQPGVKNLMNILSTATGKNVESIEKEYAGLGYSKFKKDVAEAIIAEVEPLQKEVKRYLEDKSYLEKVYKEGAQKASYVANKTLSKMKRKIGFVLDK
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_HAEIN
Sequence: MKQSIIIPALDLINGQVVRLHQGDYAKQTTYSDNPIKQFDNYVRQGAKQLHLVDLTGAKNPQSRQTALIGKIVEATQCKVQVGGGIRTEQDVADLLAVGANRVVIGSTAVTHRSMVKNWFIKYGAEKFVLALDVNINASGQKIVAISGWQEESGVLLETLIEDFQTVGLQQVLCTDISRDGTLTGSNIGLYQEICEKYPPIQFQSSGGIGSLADIEALKGTGVSGVIVGRALLEGKFTLSEAIKCWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_BLOFL
Sequence: MIFTLKLFKKLFRNRNERILVHMKKIVDMINYMEKDMEKLNDNQLSNKTNEFRMQIKSGINIEELLPQAFAVVRESVKRIFNIRLFDVQMLGGIVLNNRCIAEMRTGEGKTLTATLPAYLNALTGKGVHIVTVNNYLAHRDATYNQPLFEFLGLNVGINLPGQTVCAKKIAYESDITYGTNNEYGFDYLRDNMVFNVKEQVQRELHYALIDEVDSILIDEARTPLIISGPSDDASLSYLKINELVCNIIKRNIDHCKYPEKEEYFTVDEKSRQVVLTEIGLILIEKLLIESGMMGMGESLYSSDNIILLHHVNSALRAHILFACEVDYIVKNGEILIIDEHTGRVMPGRRWSDGLHQAIEAKERVRIQNENQTLASITFQNYFRLYEKLSGMTGTASTESFEFKSIYKLDTVVIPTNQPMIRIDFPDVIYMTEIEKINAIVSDIKDCVNRKQPVLVGTVSIDKSEIISRALKKEGILHKVLNAKIHAAEADIIAQAGYPGAVTIATNMAGRGTDIVLGGNWRSEIAALRNANTHAMLRIKSDWKERHDSVLKSGGLHVIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDSLIRIFASNKLVDLMKRMGMKSGESIEHPWITKAIAHAQKKVESRNFDIRKQLLEYDDVANDQRRVIYEQRNKLLAMLDVSEVIHNIRYDVVDRILNIYIPLEIIENKKDLIKLEKCLKDDFNLVLSFSEQLDEDTSLYEGKEKIRVCILTEMIKQYKCVKEMVGINVMNAIEKGIILKTFDALWKEHLASMDYLRQGIHLRGYAQKDPKQEYKKESFSMFKKMLDHLQYEIISEISKLQKLNRSN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: OBG_PSEPK
Sequence: MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSVYMIADENLNTLVDYRYTRHHEAQRGSNGGSTDCTGKKGEDLFLRVPVGTTVIDASTQEVIGDLVTPGQKLMVAQGGWHGLGNTRFKSSTNRAPRQTTPGKPGEQRDLKMEMKVLADVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVIADIPGLIEGASEGAGLGIRFLKHLARTRVLLHLVDIAPLDESSPADAAEVIVNELTRFSPSLAERERWLVLNKADMVMDDERDERVQEVIDRLEWEGPVYVISAISKQGTDKLSHDLMRYLEDRADRLANDPAYAEELADLDQRIEDEARAQLQALDDARTLRRTGVKSVHDIGDDDGWDDDFEDDEDGPEIIYVRD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_DESRM
Sequence: MNLRPEEISSIIRQQIDKYEAQVEVSDVGTVIQVGDGIARVYGLEDCMAAELLEFPGGTLGMALNLEEDNIGCVIMGPYTHIKEGDPVKRTGRIISVPVGDALIGRVVNPLGQPIDGKGPIKTEKYRPTERIAPGVITRKSVTVPLQTGLKAIDAMVPVGRGQRELIIGDRQTGKTAVAVDAIINQKGQDVICIYVAVGQKASTVAGVVQTLEAHGAMEYSIVVAANASEPAPLLYLAPYSGCAMGEEFMDNGKDVLIIYDDLSKQATAYREMSLLLRRPPGREAFPGDVFYLHSRLLERAARLAPEFGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNSGQRPAISVGLSVSRVGGAAQIKAMKQVAGQLRLDLAQYRELAAFAQFGSDLDKATQARLNRGARTVQILKQGQYKPYPVEEQVVVIYTAVKGFLDDVELNKIGAFEDGFINFMRSNKADILKAIREQKEIKPETDAKLVAAIEEFKKTFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HIS5_RHOBA
Sequence: MITIVDYQMGNLRSVQKAVERSGVEAEITSDASQIAAAERLILPGVGAFGDAIGEIRRRDLEKPIKDFIASGKPFLGICLGLQMLFEQGFEGGTHEGLGVLGGDVVAFELPAEFKVPHMGWNAVDVKDAGADLGIQSGTHFYFVHSYFVRPADPSVVALTCDYGGEFCAAVRRGNLMATQFHPEKSQGDGLRLMQRFATAPVEVA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_PSEPW
Sequence: MKEWLDEIKWNSDGLVPAIAQDHKTGRVLMMAWMNRESLALTAAEQRAIYWSRSRGKLWRKGEESGHVQKLHEMRLDCDADVIILMVEQLGHIACHTGRESCFYRVFEDGQWKTVDPVLKDPDAIYNAGH
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.