PharMolix/UniProtQA huggingface dataset:
Protein: NAGS_PICPA
Sequence: MLSIKDFTSNLTRHARNTEEKRNMVLTILNSTATKREVRNYLKKYPLLKDVDIYSKGQMDRSSVSKRNKYSSMIDNLMLKHSTNNENNKIEDFHLNRPRSDLISKSKLEIKLTDTLRIAIVKIRQFRDIDPTALKGIAFTLYKLIKLGVSPIVLLDTDKEVQALNGESDAMVQKSIANYHQQALSFINIIEKCFHKYEDDNELSARAIRGLFEQKFDEDRFSMTLPELLLIPISQGIVPVVYPVGYMDKGSKNVFLSSEAVLQCLATDLKSLNDRHRLDHDKENLFTIEKYIFIDPLGGIPSLERYKSAHVYINLLQEYEDIVSELYIGFLKTGERDQHLKNLNLLQKLLQVTTDASGIVTTPQIAMLNQTDRFTNPIIYNVLTDRPTISSSLPVDLKKTPLLNTSIIRRGVPVEVYVDESSDKSGLCLDSLLKRGALDLEKLKNVIDLSFRKDLNMKKYLARVKNNVAAILIAGDYEGVIIVTWEVTDEEKPQKIAYLDKFAVSPKAQGSTGVADVLFKSLLSNFENELFWRSRSNNPVNKWYFERSKGSLTVTGTNWKCFYTGKNYPSLDRMKGYFNICERIQPSWNG
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PBPA_XYLFT
Sequence: MYRLRGWLGWLLTILIILTLVGILAAGSMYYAISSKLPDIRNLKQVELQEPMYVYSHDGLLIAIFGEIRRYPVQIKEVPEQLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRVPGGSTITQQVARQFFLNSEYSYKRKLAEILLARKIESQLKKDEILELYLNKSFFGNRAYGIAAAAEFYYGKKLNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNFITQDQANAAKAIPMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGTLQMAAETSVRNGLALYEHRHRWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVARTTPEGSAIVVRSDRSELTLPPAASRWTGTPLNKLLKRGDVVRVRPGEKRGEWTLEQLPSAQSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASIVPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGIDFARNYITQFGFEENEIPPNLSMSLGTASLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKNNPKVACSSCTSANTNVTQSTSHLVDGFNFGAPTKTEPSKPVKNNNEPTQTIPSPDPNTPMAPRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPYVTTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIARNAPPQGMTQTTLNGATEWVKNEDINHLQDHDFKLHEEESDEQTFDIF
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
What are the official names of this protein?
Penicillin-binding protein 1A, PBP-1a, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: H2A2C_HUMAN
Sequence: MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHKAKSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 2-C, H2A-clustered histone 20, Histone H2A-GL101, Histone H2A/q.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ICIB_HORVU
Sequence: MRSMEGSVPKYPEPTEGSIGASGAKRSWPEVVGMSAEKAKEIILRDKPDAQIEVIPVDAMVPLDFNPNRIFILVAVARTPTVG
What is the function of this protein?
Inhibits both subtilisin and chymotrypsin.
What are the official names of this protein?
Subtilisin-chymotrypsin inhibitor CI-1B.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.
Protein: NDUCR_HUMAN
Sequence: MIARRNPEPLRFLPDEARSLPPPKLTDPRLLYIGFLGYCSGLIDNLIRRRPIATAGLHRQLLYITAFFFAGYYLVKREDYLYAVRDREMFGYMKLHPEDFPEEDVYCCGAERRG
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2, NDUFC2-KCTD14 readthrough transcript protein.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFC2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: QUEC_STAAE
Sequence: MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ATPE_AQUAE
Sequence: MIQVEIVSPQGMVYSGEVESVNVPTVEGEVGILENHMYLMTLLKPGLVYFNGDDKNGIAVTYGVLDVTPQKVLILAEEAYEVGKLPPASKLKEEFEEAVKKMATAQTMEELKEWEKEAEKARTLLELVEKYR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CFAC_DICDI
Sequence: MKVLILLVSLISVCFSQIAPKPIIVGGVYRGGETCNSLQPPYTCSSDDLAGGIMMRQGACTYFRGLSNLPTTYNSSSDGSSVIQYTYSADDYFCQESPIQTQTISNGDCEAGCSNDKISYLYNLSSDSNDQVPKNAVLTIKSQSSNCATDWETTWESIEYLNTDTCIVDEVTGGSFKVSCTQGGMTIYSYAAPGCTNNPKVYGVGFYTDSCDGYQVCSL
What are the official names of this protein?
Counting factor-associated protein C.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_BURA4
Sequence: MNYPHPIIAREGWPFIAIAAVIALLIHAVGGFGFAWPFWLLLVFVVQFFRDPQRPIPAQPNAVLCPADGRIVAVETTQDPYANREALKISVFMNVFNVHSQRSPVDGAVTKVEYFPGAFLNAAIDKASTENERNALVIQTASGKTVTAVQIAGLVARRILCYVRAGEPLSRGQRYGFIRFGSRVDVYLPLGSRAKVSIGEKVYASSTILAELEQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YPFN_SALSV
Sequence: MDWLAKYWWILVLVFLVGVLLNVIKDLKRIDHKKFLANKPELPPHRDFNDKWDDEEDWPKKDQPKK
What are the official names of this protein?
UPF0370 protein YpfN.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: OBG_YERPS
Sequence: MKFVDEAAILVVAGDGGNGCVSFRREKYIPNGGPDGGDGGDGGDIYLLADENLNTLIDYRFVKSFRAERGQNGQSRDCTGKRGKDITIKVPVGTRVLDQGTGEIVGDMVRHGQRLMVAKGGFHGLGNSRFKSSVNRAPRQKTMGTEGETRELMLELLLLADVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLIPSLGVVRMDYEQSFVIADIPGLIEGASDGAGLGIRFLKHLERCRVLLHLVDLAPIDESDPAENAKVIVNELQQYSENLAEKPRWLVFNKIDLIDPEEAEKRAKAIVETLGWEGKYYMISAANRDNVNALCWDVMSFLNSQPKAMAIAESVPEKVEFMWDDYHREQLAEVEAEAEDDWDDDWDEEDDDGVEIIYER
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANX3_MOUSE
Sequence: MSLAHTAAEYMLSDALLPDRRGSRLKGLRLELPLDKMVKFITVGFPLLLMSLAFAQEFSSGSPISCFSPSNFSVRQAAYVDSSCWDSLAHHTQDKAGQYKVKSLWPHKALPYSLLALAVAMYLPVLLWQYVAVPSLSSDLLFIISELDKSYNRSIRLVQHMLQIRQSSSDPHVFWDELEKARKERYFEFPLLERYLECKQRSHWLVATYLLRNALLLLFTSATYLYLGQFHLDVFFQDEFNCFIKTGLLHDETHVPELITCRLTSLSVFQIVSVSSAAIYTILVPVIIYNLTRLCRWDKGLLSIYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLSVLKDTTTQKHNIDTVVDFMTFVAGLEPSKPKHLTQHTYDEHA
What is the function of this protein?
Structural component of the gap junctions and the hemichannels.
What are the official names of this protein?
Pannexin-3.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: EGF_RAT
Sequence: MLFSLTFLSVFLKITVLSVTAQQTRNCQSGPLERSGTTTYAAAGPPRFLIFLQGNSIFRINTDGTNHQQLVVDAGVSVVMDFHYKEERLYWVDLERQLLQRVFFNGSGQETVCKVDKNVSGLAINWIDGEILRTDRWKGVITVTDMNGNNSRVLLSSLKRPANILVDPTERLIFWSSVVTGNLHRADLGGMDVKTLLEAPERISVLILDILDKRLFWAQDGREGSHGYIHSCDYNGGSIHHIRHQARHDLLTMAIFGDKILYSALKEKAIWIADKHTGKNVVRVNLDPASVPPRELRVVHLHAQPGTENRAQASDSERCKQRRGQCLYSLSERDPNSDSSACAEGYTLSRDRKYCEDVNECALQNHGCTLGCENIPGSYYCTCPTGFVLLPDGKRCHELVACPGNRSECSHDCILTSDGPLCICPAGSVLGKDGKTCTGCSFSDNGGCSQICLPLSLASWECDCFPGYDLQLDRKSCAASMGPQPFLLFANSQDIRHMHFDGTDYKTLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANLDGSQRERRITEGVDTPEGLAVDWIGRRIYWTDSGKSVIEGSDLSGKHHQIIIKESISRPRGIAVHPKARRLFWTDTGMSPRIESSSLQGSDRTLIASSNLLEPSGIAIDYLTDTLYWCDTKLSVIEMADLDGSKRRRLTQNDVGHPFSLAVFEDHVWFSDWAIPSVIRVNKRTGQNRVRLRGSMLKPSSLVVVHPLAKPGADPCLHRNGGCEHICQESLGTAQCLCREGFVKAPDGKMCLTRKDDQILAGDNADLSKEVASLDNSPKAYVPDDDRTESSTLVAEIMVSGLNYEDDCGPGGCGSHAHCISEGEAAVCQCLKGFAGDGNLCSDIDECELGSSDCPPTSSRCINTEGGYVCQCSEGYEGDGIYCLDVDECQQGSHGCSENATCTNTEGGYNCTCAGCPSAPGLPCPDSTSPSLLGKDGCHWVRNSNTGCPPSYDGYCLNGGVCMYVESVDRYVCNCVIGYIGERCQHRDLRWWKLRHADYGQRHDITVVSVCVVALALLLLLGMWGTYYYRTRKQLSESSKKPSEESSSNVSSNGPDSSGAGVSSGPQPWFVVLEEHQQPKNGRLPAAGTNGAVVEAGLSSSL
What is the function of this protein?
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.  Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
What are the official names of this protein?
Pro-epidermal growth factor, EGF.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ERYH_BRUME
Sequence: MTKFWIGTSWKMNKTLAEARLFAEALKAADAGRSPDIQRFVIPPFTAVREVKEILSGTSVKVGAQNMHWADQGTWTGEISPLMLKDCNLDIVELGHSERREHFGETNETVGLKVEAAVRHGLIPLICIGETLEDCESGRAAAVLEEEVRGALSKLSEAQKQAEILFAYEPVWAIGENGIPASADYADARQAEIIAVAQSVLARRVPCLYGGSVNPGNCEELIACPHIDGLFIGRSAWNVEGYLDILARCATKVQAN
What is the function of this protein?
Catalyzes the isomerization of D-erythrulose-4P to L-erythrulose-1P.
What are the official names of this protein?
L-erythrulose-1-phosphate isomerase, D-3-tetrulose-4-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_NITEU
Sequence: MGTIFHLDIVSAEESIYSGPAEFIVAPAVMGEVGIFPQHTPMLTRIKSGVVRVKAPLQDDEEVYVSGGMLEVQPDVVTILADTAVRGKDLDEAKALEAKRKAEEIMKNKISEIEYARAQAELIEATAQLAAIQKLRKRGH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRB_IGNH4
Sequence: MPDVVDVLDLDKKDMIKIFELAEDIEYKKLHKSKWCALENKTVSLLFVEPSTRTRLSFEESAKRLCAHTLTIVGEEASSFVKGESLYDTIKVLDKISDIIVIRHNLDGSAKYASEVAANPVINAGDGKNQHPTQSLIDLYVVRKRKGGLEDLRYAVVGDLRYARTARSFLLALTKFKPRSVYLVAPEVLKPSIKFLEELKSMGLNVFEVDRLEDVIPNVDVIYVTRIQKERFPDPSEYEKVKGSYKITLDLIKRGKGDLIVLHPLPRVDELDVRIDSTPHAAYFDQVAASVPVRMATLAWSAGVV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PROA_CUPPJ
Sequence: MTELDLNQYMDRVGRQARAASRAMARASTADKNRALLTIAAAIRRDADKLKAVNARDVERARANGQDAAFVDRLTLSDKAIKTMAEGLEQIAALADPIGEISNMKFRPTGIQVGQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEAIESNTALAALVAEGLASAGLPPEAVQVVETTDRAAVGRLITMTEYVDVIVPRGGKSLIARLMEEARVPMIKHLDGICHVFIDADADLDKAVRVCDNAKTQRYAPCNTMETLLVSQDIAARALPPLCRIYQEKGVELRVCPATRAMLEAAGFSGLVDAHEEDWRLEYLAPILAIKTVAGLDEAIAHINEYGSHHTDSIITENYSTGMRFIREVDSASVMINASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVVFGHGEIRT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NB_RENSM
Sequence: MPVEIPRDLTPELVPLSWLLGQWEGQGRLGTGEAESEHFFQRVTFSSNGLPYLEYVAESWLTDEEGMKLRPLSVEMGFWALDRKLGEADGGPGLIPADIVPALTTADDVEKLRNDTSGFDITATIVHPGGISELYYGTIKGPQIELSTDAVMRGAGAKDYSAATRIFGLVNGDLFWRWDVAAEGNSLEAHASAILKKTAAPESAEQRPSE
What is the function of this protein?
Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate.  Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively).  Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
What are the official names of this protein?
Peroxynitrite isomerase, Ferric nitrobindin, Nb(III).
What is the protein family that this protein belongs to?
Belongs to the nitrobindin family.
Protein: SYH_CROS5
Sequence: MGTIQTLPGTRDILPEEIGYWQYVETVATQILSRAMYYEIRPPIFEQTSLFERGIGEATDVVGKEMYTFSDRGDRSLTLRPEGTAGVVRAYLQNNLYAAGGVQRLWYCGPMFRYERPQAGRQRQFHQIGLELIGTADPRADVEVIALATDILKTLGLQSLKLDINSVGDRNDRQNYREALVNYFLPYKAELDTDSQDRLQRNPLRILDSKDKRTKEINQNAPSILEHLGDASKKHFDQVQQLLTDLGIEYNINPCLVRGLDYYTHTAFEMISDDLGAQATVCGGGRYDGLVEELGGNPTPAVGWAIGMERLIILLKQLQSSPDMTPDIYIVSRGEAAEGQGLILAQKLRKEGLTVELDMSGSAFGKQFKRADRSGAIACIVLGEEEATNKTVQLKWLQSKEQQAMTQAELLTKVGELIEQLDRHKRTMNHSTQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_BORBR
Sequence: MSKIIGIDLGTTNSCVAVLDGGQVKIIENAEGARTTPSIVAYMDDGETLVGAPAKRQAVTNPKNTLYAVKRLIGRKFDEKAVQKDIDLMPYSIVKADNGDAWVEVRGKKLAPPQVSAEVLRKMKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGLDKTEKGDRKIVVYDLGGGTFDVSIIEIADVDGEMQFEVLSTNGDTFLGGEDFDQRIIDYIISEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSSQQTEINLPYITADASGPKHLNLKITRAKLEALVEELIERTIEPCRVAIKDAGVKVSDIDDVILVGGMTRMPKVQDKVKEFFGREPRKDVNPDEAVAAGAAIQGSVLSGERKDVLLLDVTPLSLGIETLGGVMTKMIQKNTTIPTRYSQTFSTADDNQPAVTIKVFQGEREIAAGNKGLGEFNLEGIPPAPRGLPQIEVTFDIDANGILHVSAKDKGTGKENKITIKANSGLSEDEIQRMVKDAEANAEEDHRLAELAQARNQADALVHATRKSLTEYGEKLEAAEKESIEAAIKDLEDILKTGDKAEIDAKVEALSTASQKLGEKMYADMQAQQQAQQQQAADNAKPVDDNVVDADFKEVKRDQ
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SDHF2_SCHPO
Sequence: MLRKTNLSNITTLLRSARCMNRMPQLRFEHTKGDLKRVNRSYETRDAMLARLKYQSRKRGILETDLLLSNFAKDQIDKYPVSLLREYDQLLDEPDWDILYWCSGEREAPEKWKSSQVFKELSKYCRSQRNHTLRMPELF
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix.
Protein: KHSE_XYLFT
Sequence: MNRTLQPDSGASQTAPTAHQARAFAPASVANVAVGFDLLGYPMDQVGDTVTVRRIDTPQVRIAAIRGIAQPLPLQTERNTAGAALLSMHRDLALPFGFELEIDKGIPLSSGMGGSAASCVAALLAANALLDEPLRREHLYRYALDGEAVASGSRHGDNLGPLFLGGLVLCTLERLVPVTVPTAWHSLLVHPDTLLETRRAREVLKEPYLLPDIVTQSANLALVLAGCYHSDAELVRAGLRDVLIEPRRAPLIAGFTAAQQAALQADAMGASISGAGPSVFAWFQTRSAAEAAAPAVRAAFTAAGFDSQAWVTPLTSPGARLL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_MYCS2
Sequence: MSVLLFGVSHRSAPVSVLEQLSTNEAEQAKIIDQVLQSSLVTEAMVLSTCNRVEVYAVVEAFHGGLSVIGQVLAERSGMSLNDLTKYAYVRYAEAAVEHLFAVTSGLDSAVIGEQQVLGQVRRAYATAEANRTVGRTLHELAQRALSVGKRVHSETGIDAAGASVVSVALGMAETKLSGGLGGRTAAVVGAGAMGALAGAHLVRAGIERVHVVNRSLPRAERLAKNLTEQGVVADAVGLDDIARALVDADVVLSSTGAVRPVVSLADVHYALAQRTLAGAEHQMVVCDLGMPRDVDPAVSGLPGVWVVDMDRIQREPSARAAAVDAEAARNIVAAEVANYLAGQRMAEVTPTVTALRQRAADVVEAELLRLDNRLPGLDAAHRDEVAKTVRRVVDKLLHAPTVRVKQLASAPGGDSYAEALRELFELDPQAVEAVAASELPLITTDLDKTE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SPP2_EMENI
Sequence: MPSSPPPDGGNANKTSIKPVSLSLGSSKKLPIKKPVSSHTLARRPHHNLPYHHDSDSDDNGGDSEPAFQSVTGFDTLTGRTLDASGAEEKKPLTIPVASGNNWRDRPGVIRRSKGKNLLPKEVQALQEAQSKGEVPGDGDAVGPSMQYGLSFAKQPQNDGGDQKMEDAALPAVEAAEKAKPLTEDEIALQALVRESRGEVEGRSDLVIESTRAGEGEAEEDVNEFYDGHNSETRSFRADVAARPESATLEQYNTIPVEEFGAALLRGMGWKEGQAVGKGKYGSADPSRASTPHIPARRPGFLGIGAKDVSNGKAEVELGAWGKAAMRKGSKKAGEATKNGEGNTEGIYMPVLMRNKKTGEMITEEELAAMAKEAKKRDDSEDWKEERDRNSERSERDKDHHRDRDRDRDSRRLEYDDTYRYESRRNGSSRRDRSRSTSDRHSRRRKYEGDDGDRRDDRYYRDRDRERRSDPVRDRDRNRDRKSRYYDDDRNSSWYSSSTASSKQRNRDRDRDRDNDRDSRRRK
What is the function of this protein?
Involved in spliceosome maturation and the first step of pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor spp2.
What is the protein family that this protein belongs to?
Belongs to the SPP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYLA_CERSK
Sequence: MTDFFAGIPQIRYEGEGSSNEFAFRHYNPDEVILGKRMEDHLRFAVAWWHSFAWPGGDPFGGQTFDRPWFGDTLDLAKLKADVAFEMFDILGAPFFCFHDADIRPEGATFAESKRNLEEIVDHIGTRMEGSKTKLLWGTANLFSHRRFMSGAATNPDPDVFAWSAATVKGCMDATMKLGGANYVLWGGREGYETLLNTDLTREAENAGRFLQMVVDYKHKIGFQGTILIEPKPQEPSKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALAASLGILGSIDMNRNDYQSGWDTDQFPHNHPEMALAYYEILRAGGFTTGGTNFDAKIRRQSLDPEDLVLAHVGGMDTCARALKAAARLYEDGSLETARAARYAGWETPEAQAMLASSLEEIEARVLAEGINPKPRSGRQERLENLWNRFV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKRN2_HUMAN
Sequence: MSTKQITCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity).  Promotes the polyubiquitination and proteasome-dependent degradation of RELA/p65, thereby suppressing RELA-mediated NF-kappaB transactivation and negatively regulating inflammatory responses (By similarity).  Plays a role in the regulation of spermiation and in male fertility (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase makorin-2, RING finger protein 62, RING-type E3 ubiquitin transferase makorin-2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ASK5_ARATH
Sequence: MSTKIMLKSSDGKSFEIDEDVARKSIAINHMVEDGCATDVIPLRNVTSKILKIVIDYCEKHVKSKEEEDLKEWDADFMKTIETTILFDVMMAANYLNIQSLLDLTCKTVSDLLQADLLSGKTPDEIRAHFNIENDLTAEEVAKIREENQWAFQ
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).
What are the official names of this protein?
SKP1-like protein 5, AtSK5.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMH_PORG3
Sequence: MHCPDKESVYHIPVMLGECLEGLRIDPDGCYVDVTFGGGGHSRAIVEKLSSKGRLYGFDQDADACRNVLQDERFTFVPSNFRYLANFMDYYGEDGVDGILADLGVSSHHFDEEERGFSFRSESPLLDMRMNARAGRNAAAILNEYDASSLSALFYHYGELKQARRLAASIVHYRESLSGGLQTVGQLLEAVRGLISPREEKKQLACIFQALRIEVNDELGALQQMLEAALGCLRSGGRLVVMTYHSLEDRMVKNFLRYGTVKAPDEDSLRLYGAPQSPWQQITRKPLTASTKELSDNPRSRSAKLRIAEKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.