PharMolix/UniProtQA huggingface dataset:
Protein: PSBA_MAGPY
Sequence: MTAILERRESTSLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YCIZ_ECOSM
Sequence: MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVAESTPDIPKAPWEI
What are the official names of this protein?
UPF0509 protein YciZ.
What is the protein family that this protein belongs to?
Belongs to the UPF0509 family.
Protein: UBIE_SALEP
Sequence: MVEDSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRMVGETGKVILADINDSMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTEKEKALRSMFRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHILPRIGSMVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RL28_CLOBA
Sequence: MARRCEICDKGVVAGVQFSHSHRQSKRTWAPNIKKIKALVNGTPKTVRVCTRCLRSGKVQRAI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RL4_BACC7
Sequence: MPKVTVYNQTGSQVGEIELAEAIFGIEPNEAVLFEAVMMQRASLRQGTHKVKTRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGTVFGPTPRSYAYKLPKKVRRLAIKSALATKVVENNIVVLEDLVLNAPKTKDMLAVLKGLTVEKKALIVTADANESVELSARNIPGVTVITADGVNVLDVLHHDKLIMTKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CSN9_ASHGO
Sequence: MIRQEVLHAVLDPKAVHFKQFWLSSVDRDESELLEVLCFGNYGDLNAIQSCEEWKDAIESKLRTLTLLGLCEVPSELEYDQAMASCCIPDDVILEQRMVELQAQVHFQLDSVGRRIKVLRCLGARDIYNGERPLLLLRDAARSRESTLAGLRQWKQKLQYQLR
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as a regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.  The complex is involved in the regulation of the mating pheromone response (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 9.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MSCL_ECOBW
Sequence: MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS19_PICTO
Sequence: MVAKRQVSVKSIKRKARKAQKAITGRAKEFSYRGHSLEELQNMELNELLPLLPARARRSYSRQMNHEQEKLYEKLLGDKENIKTHVRDLIVLPQFVGKTIELYNGNSYIKFEIKPEMIGHYLGEFALTRKEVKHSGPGVGATRSSKFLPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FMT_POLAQ
Sequence: MKIVFAGTPEFAAQAMRAIHAAGHEIVLALTQPDRRAGRGMHLQASPVKEFALEKNIPVLQPETLRRNNKDPEKQQQAEDAYRALINTNFDAMVVVAYGLILPQEILDITQQAPRFGSFNIHASLLPRWRGAAPIQRAIEAGDAKTGVCIMQMEAGLDTGDVVLTADLAIASDETSSSLHDRLAALGAGLIVDALSLLQDGKGLSRTPQPALGVTYAEKILKAEADLDWSLSAREIDARIRAFNPFPGAISNLNAETIKLWKSRLADEDAYSEAGPIGAVIGFSEDGVFVRCGDGVIEILEAQKPGGKKMNAKTCLQSVDAPEKLLCFQTKA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: YR632_MIMIV
Sequence: MKEIVYYDFDLDLNPEIRWVKIFDAFKDKITELKSHLVNLLKPHDSSLKVISMLSGFINPENILHYGEIKYITSKLGMKMYEIIILQLVYEITAACTSAVIDVGDNKLFLRTLDWPLEFLKDFTIGLNIIRANKKIGQTITWIGYVGFLTAWNHKHNYTIAINYRNSNESNQSRLAKIIKNIQRTITLKWPVGYMVRYLIENEKPIEKVIAFTTEVQLISPCYITVYISDGQSFVVTRDCHKTVDIRTDNLIQTNCDFGKNKPNILYSVERRDYVESVIASITTDISPDKLIKTLLKFPVVNEDTIFWVCQFEGKTYSNIV
What are the official names of this protein?
Uncharacterized protein R632.
Protein: Y1151_SHEPW
Sequence: MPSMDIVSEVNEVELRNAVDNSVRELKSRFDFRGKEASIEYKDHVVTLSAEDDFQCQQLVDILRMQMSKRNVDPKSMDVDDKAVHSGKTFSLRVKFKEGIETLIAKKLVKLIKDSKLKVQSSIQGDSVRVTGKKRDDLQAVMALAREADLGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein swp_1151.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: GIN1_MACFA
Sequence: MVRSGKNGDLHLKQIAYYKRTGEYHPTTLPSERSGIRRAAKKFVFKDKKLFYVGEDRKQNRLVIVSEEEKKKVLRECHENDSGAHHGISRTLTLVESNYYWTSVTNDVKQWVYACQHCQVAKNTVIVAPKQHLLKVENPWSLVTVDLMGPFHTSNRSHVYAIIMTDLFTKWVVILPLCDVSASEVSKAIINIFFLYGPPQKIIMDQRDEFIQQINIELYRLFGIKQIVISHTSGTVSPMETTPSTIKAFLSKHCADHPNNWDDHLSAVSFAFNVTHLEPTKNTPYFQMFSRNPYMPETSDSLHDVDGDNTSMFAKILDAIKEADEIMENKTTSLGQMENNNLDELNKSKIIVKKKPKQLNPFHLKVGHEVLRQRKNWWKDGRFQSEWVGPCVIDYITESGCAVLRDNTGVRLKRPIKMSHLKPYIRESSEQESLYLLQGSVVADHDYIGLPEIPVGAYQANILVEDATIGIVDNELLTSSKDRELLEYRNTKISPLIDDHSTLEKQTFSLLDSSNQVLEYLS
What are the official names of this protein?
Gypsy retrotransposon integrase-like protein 1, GIN-1.
Protein: KATG_LEPBP
Sequence: MRNFRRFTIALLVLFLGPIGAADTKETPGMDRQNTSNQFWWPERLDLAPLRQHGSESNPLGRQFHYAKEFKELDIQTLKEEIKTVMKTSQDWWPADYGHYGPFFIRMAWHSAGTYRISDGRGGAGGGQQRFEPLNSWPDNANLDKARRLLWPIKKKYGKKISWADLMVLTGNVALESMGFKTYGFAGGRTDDWEADLVYWGPEKKFLEDQRYKGNRELKNPLAAVQMGLIYVNPEGPNGNPDPLAAAKDIRETFGRMAMNDEETVALIAGGHTFGKAHGKSDPSKHVGKEPAAAGLEEQGFGWKNNYKKGNAEDTITSGLEGAWTANPTKWTTQYLNNLFGFEWVQTKSPAGAIQWVPKDGAGANMVPDAHDKSLRHAPIMFTTDLALKFDPSYKVIAKRFQENPKEFELAFAKAWFKLTHRDMGPLTRYIGKDLPKEPLIWQDPVPAVNHKLVGPKEIESLKGKILKSGLSVPQLVRTAWASAASFRSTDMRGGANGARIRLSPQKNWPVNDPDELSKVLKKLEQIQEEFNKSGNKISLADLIVLAGNAAIEEAAKKAGVKVTVPFTPGRTDATIEQTDEYSFSVLEPKADAFRNYYGPGNLMSPTEMLVDRANMLSLSIPEMTVLLGGMRSLDANAGKSKHGILTTKPGVLSNDFFVNLLDMSTKWQKSEQTEGLYEGLDRKTGSKRWTATSVDLIFGSHSELRAVAEVYASDDAKEKFVKDFVSAWNKVMMLDRFDVK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: NDHI_DELBI
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: NUOB_BRADU
Sequence: MEERGTGMGLNPAPSTGPVLAPAPKGILDPSTGKPVGANDPFFLEVNSELSDKGFFVAATDDLITWARTGSLMWMTFGLACCAVEMMQVSMPRYDVERFGFAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPIDIYVPGCPPTAEALLYGVLLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS6_PELUB
Sequence: MNLYEHTIVARQDTSPAQVKQLTEKYSKIVEKNEGEIVQTEDWGLLNLAYIIKKNKKGIYMHFKIKGPGKIIDELEKNEAIDKNLLRYMTVKVKKFNLEAKYFSKKDEYEKKEYKKEYNRD
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: BIOF_ECO7I
Sequence: MSWQDKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWKLGAEQFGVGSGGSGHVSGYSVAHQVLEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSPLRRFAHNDVTHLARLLASPCPGQQLVVTEGVFSMDGDSAPLEEIQQVTQQHDGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSNTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLVSLIARFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGND
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SYT_ACIB5
Sequence: MPIITLPNGDQKSFDHPVSVMEVAQSIGPGLAKNTVAGRVNDRLVDACDLITEDSTLQIITPKDEEGLEIIRHSCAHLVGHAVKQLFPEAKMVIGPVIEEGFYYDIWMPRPFTLDDMAAIEERMKKLIDQDYDVIKKMTPRDEVIKVFTDRGEEYKLRLVEDMPEEKAMGLYYHQEYVDMCRGPHVPNTKFLKSFKLTKISGAYWRGDAKNEQLQRIYGTAWADKKQLAAYIKRIEEAEKRDHRKIGKALDLFHMQEEAPGMVFWHANGWTIYQVLEQYMRKVQQDNGYQEIKTPQIVDFTLWEKSGHAANYVENMFTTHSESRNYAVKPMNCPCHVQVFNQGLKSYRDLPIRLAEFGSCHRNEPSGSLHGIMRVRGFTQDDAHIFCTKEQIGKEVADFIKLTLDVYKDFGFEEVQMKLSTRPEKRVGDDALWDLAEKSLADALDAAGLEWELQPGEGAFYGPKIEFSLKDCLGRVWQCGTIQCDFNLPVRLDASYVTEENERDQPVMLHRAILGSFERFIGILIEHYAGFMPPWLSPVQACVMNITDSQAEASEQVVAKLKENGLRAISDLRNEKIGFKIRERTLERIPYLLVLGDREVEEGTVNVRTRSGKNLGTMSVDAFIDLVKSAVAERGRYIVE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_STAHJ
Sequence: MASLKSIIRQGKQTRSDLKKLRNTGKVPAVVYGYGTKNTSVKVDEVEFIKVIREVGRNGVIDLGVGSKSIKVMVSDYQFDPLKNQITHIDFLAINMTEERTVDVPVHLVGEAAGAKEGGVVEQPLFDLQVTATPENIPESIEVDITELEVNDSYSVSDIKVSGDFTIENDPEESVVTVVPPTDEPTEEEVEAMEGEAATEEPEVVGEEKEEDSEEENKDEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: TGT_PROMA
Sequence: MFDFKVLSRSTNTAGRVGRLSTPHGILSTPQFMPVGTLGTVKGITATQLKDTNAQMILANTFHLHLQPGEAIIKESGGLHSFMSWDQPILTDSGGYQVFSLGKLNKIDDFGVSFKSPRDGSHIELTPEKAIQIQMDLGADVVMAFDQCPPYPASKVEVEEACKRTHLWLERCVATHSKEDQALFGIVQGGCFLDLREESARRVASFHLPGIAIGGVSVGEPSDQIHKIVRHVAPLLPNEVPRYLMGIGTIREMAVAVANGVDFFDCVLPTRLGRHGTALVRDERWNLRNACFRNDYQPLDTTCVCETCTNYNRAYLHHLIRNDELLGLTLLSLHNLSHLIRFSRAMAVAIEDDCFSEDFAPWQKSSIAHYTW
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RL13_PSYWF
Sequence: MKTQSAKPAEVTHDWYIVDAEGKTLGRLATQIAARLRGKHKPSFTPHVDTGDYIVVINADKIAVTGKKAQDKKYYRHSGYPGGIKETNFTKLIAHKPEEVLLKAVKGMLPKGPLGYATIKKLKLYAGTEHPHAAQQPKELDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DYLT_DROME
Sequence: MDDSREESQFIVDDVSKTIKEAIETTIGGNAYQHDKVNNWTGQVVENCLTVLTKEQKPYKYIVTAMIMQKNGAGLHTASSCYWNNDTDGSCTVRWENKTMYCIVSVFGLAV
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  Required for spermatid differentiation.  Is not required for polarized transport in rhabdomere development and appears to be a non-essential component of the cytoplasmic dynein complex.
What are the official names of this protein?
Dynein light chain Tctex-type, TCTEX-1 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ISPF_BURVG
Sequence: MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRECAARVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGDGIEAQAAALLVK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: LIPA_WIGBR
Sequence: MKSISYLNTKEKNKKKLSIPSKTIFAKENEYGLKKPNWLKIKLPLNNKKINKIKLIMRKNNLHTVCEEAACPNLAECFNRGTATFMILGSICTRRCPFCNVSSGRPSLVDTKEPENLSKAAIKMKLKHIVITSVDRDDLKDGGSEHFSNCIRFIRKKNPDIKIEILVPDFRGCTELALNNISTYPPDIFNHNLESIPRLYSKVRPGANYKRSLELLEKFNLINPNIPTKSGLMLGLGETKEEIIEVMKDLRKSYVSMITIGQYLRPTKNHLTVNRYVHPKEFRELNLIAFDLGFKHAMCGPLVRSSYHAENQINCY
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_ROSDO
Sequence: MSDQKKLRLGVNIDHVATVRNARGGAYPDPLRAARIAEEAGADGITAHLREDRRHISDADIEGLMDVLSVPLNFEMAATDEMQQIALRHKPHAVCIVPEKREERTTEGGLEVAREENVLAHFIAPLREAGCRVSIFIAAEQRQIEAAHRIGAEVIELHTGAYCDAHAEGDFAQRDAELARLRDMATFAHGLGLEVHAGHGLTYDTVQPIAAFPEVIELNIGHFLIGESIFRGLEPAIAEMRRLMDAARA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_SOLUE
Sequence: MRAEPALLELKLDYRFNDPELLRRALTHSSLANENRPGAGVGSPLNDNEQLEFLGDSVLGFLIAEALVRRFPEYHEGDLSRLKAHLVSAAHLHGVARRLDLGSYLELGRSEEMSGGRTKKTLLVDGLEAIMAAIYLDGGVDAARAFVATHVLDAPFFGDEEAGTDIQPAITNFKSALQELAQTRRLPQPRYSVVRERGPEHSKTFTVEVRVGKEWTAQAEGRTKKIAAQRAARGLYERLMGDPIVPLPDDSPGDSPDDSGDAAESGVISAT
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_METST
Sequence: MARKIFKFRGYTLEELQEMSLDEVIELLPSRQRRSLKRGFLPRQEKVLDKMEKVKDMKNDSGRPIVIKTHCRDMIVLPNMVGYTFGIYNGQEFVEVTIQPEMIGCYFGEFAQTRGRVQHGDPGMGATRSSMFVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: TM119_MOUSE
Sequence: MVPWFLLSLLLLARPVPGVAYSVSLPASFLEDVAGSGEAEGSSASSPSLPPPGTPAFSPTPERPQPTALDGPVPPTNLLEGIMDFFRQYVMLIAVVGSLTFLIMFIVCAALITRQKHKATAYYPSSFPEKKYVDQRDRAGGPRTFSEVPDRAPDSRHEEGLDTSHQLQADILAATQNLRSPARALPGNGEGAKPVKGGSEEEEEEVLSGQEEAQEAPVCGVTEEKLGVPEESVSAEAEGVPATSEGQGEAEGSFSLAQESQGATGPPESPCACNRVSPSV
What is the function of this protein?
Plays an important role in bone formation and normal bone mineralization (PubMed:26207632, PubMed:22416756, PubMed:20025746).  Promotes the differentiation of myoblasts into osteoblasts (PubMed:22416756, PubMed:20025746, PubMed:22579779).  May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed:21239498, PubMed:22579779).  Up-regulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed:24362451).  Essential for normal spermatogenesis and late testicular differentiation (PubMed:26207632).
What are the official names of this protein?
Transmembrane protein 119, Osteoblast induction factor, OBIF.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Endoplasmic reticulum membrane.
Protein: RUTF_ECO45
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMELRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: RL4_NEIMA
Sequence: MELKVIDAKGQVSGSLSVSDALFAREYNEALVHQLVNAYLANARSGNRAQKTRAEVKHSTKKPWRQKGTGRARSGMTSSPLWRKGGRAFPNKPDENFTQKVNRKMYRAGMATILSQLTRDERLFAIEALTAETPKTKVFAEQVKNLGLEQVLFVTKQLDENVYLASRNLPNVLVLEAQQVDPYSLLRYKKVIITKDAVAQLEEQWV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: TIG_MYCMM
Sequence: MKSSVEQLSPTRVRIKVEVPFAELEPDFQRAYKELAKQVRLPGFRPGRAPVKLLEARFGREAMLDQIVNDAVPSRYGQALAESEIQPLGRPDIEVTQKEYGQDLAFTAEVDVRPEIALPDLTGLSVSVDAIEATDDEVNAELESLRARFGTLTEVERPVATGDFISIDLSAAVDGEDVPNAAAEGLSHEVGSGRLIAGLDDAVVGLSVDESRVFTAKLAAGDHAGRDAEVTVTVKSVKERELPEPDDEFAQLASEFDTIDELRASLREQVLQAKRVGQAEQIRNATIDALLERVDVPTPESYVQAQYEGVLHSALSGINNDEARFNELLVEQGSSRDAFDAEARTASEKDVKRQLLLDALADDLKVQVGQEDLTERLVLTSRQYGIEPQQLFAYLQENNQLPSMFADVRRELAVKAVAQAATVTDTDGNTIDTSEFFGKPPENDVTDLLDDDADGDAGVDADGDTENSAEPADADSADAAQGAG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.