PharMolix/UniProtQA huggingface dataset:
Protein: ICT1_YEAST
Sequence: MWTNTFKWCSKTEKETTTADAKVCASVQGLKALQQQIMDSTTVRGSVNNTMTPGGINQWHFHNKRANKVCTPTVLIHGYAASSMAFYRTFENLSDNIKDLYAIDLPANGASEAPALQVNKTKKIKSLRFKHIEDDVVIPVIEKRPPAEDIKSHLEQYESYFVDRIEQWRKDNKLRKINVVGHSFGGYISFKYALKYPDSIEKLCLISPLGVENSIHAITHKWEPNTTYPLTFTDPSSRYYTRKLNVPRFIFENQLNVLKWMGPIGSKLCSNYISTAYVKVPDQIYKDYLLHSFVGKNQTVQPQTIKVFTHLFERNLIARDPIINNVRFLNPATPVMFMYGEHDWMDKYAGYLTTESMLKNKAKASYVEVPDAGHNLFLDNPQHFASSLVSFLSK
What is the function of this protein?
Lysophosphatidic acid acyltransferase involved in membrane remodeling leading to increased organic solvent tolerance.  Involved in resistance to azoles and copper.
What are the official names of this protein?
1-acylglycerol-3-phosphate O-acyltransferase ICT1, Increased copper tolerance protein 1, Lysophosphatidic acid acyltransferase ICT1, LPAAT.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.
Protein: NU4M_RAT
Sequence: MLKIIFPSIMLLPLTWLSANKKIWTNVTSYSFLVSLLSLSLLWQNDENYLNFSVMFSSDPLSTPLIILTTWLLPLMMLASQNHMKKENMMHQKLYISMLISLQILLIMTFSATELILFYILFEATLIPTLIIITRWGNQTERLNAGIYFLFYTLIGSIPLLIALISIQNSMGTLNFLILSLTTHPLPSTWSNTILWLACMMAFMIKMPLYGVHLWLPKAHVEAPIAGSMILAAILLKLGGYGMMRVSIILDPLTKSLAYPFIILSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVITAIMIQTPWSFMGATMLMIAHGLTSSLLFCLANTNYERIHSRTMIMARGLQMIFPLMATWWLLASLANLALPPLINLMGELFIVMATFSWSNPSIILMATNIVITGIYSMYMIITTQRGKLTSHMNNLQPSHTRELTLMALHIIPLMLLTINPKLITGLTM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LYTR_STAES
Sequence: MKALIVDDEPLARNELQYLLNLNDAIDEIEEAENIEETLEKLLYNTFDLIFLDINLMDESGIDLAQKINKMKRSPHIIFATAHEKFAVKAFELNATDYILKPFEKERINQAVNKVDMAKDKSKNKDKTITPKYIDYSDDERAQTHVLPIEVDERIHILNFTDIIALSVNNGITTIDTTKQSYETTETLNHYEKKLPSSLFIKIHRATIVNKEHIQTIEHWFNYTYQLTLTHEFKYQVSRSYMKTFKQQLGLQ
What is the function of this protein?
Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism.
What are the official names of this protein?
Sensory transduction protein LytR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB27B_ARATH
Sequence: MGFLVAVMNFSPTLVHHHMKSKPQCQNEKLRQGQTSSLFDRRGFLKCVVGASSFMATIEFSGLQAQASEEKLDEGEGVVGAFKTLFDPNERTKSGKELPKAYLKSAREVVKTMRESLKENPKDNAKFRRSADAAKESIRDYLSNWRGQKTVAGEESYVELENVIRALAKFYSKAGPSAPLPDEVKTEILDDLNKAEEFL
What is the function of this protein?
Required, but not essential, for D1 (psbA) precursor processing and thus correct photosystem II assembly (PSII).
What are the official names of this protein?
Photosystem II D1 precursor processing protein PSB27-H2, chloroplastic, Psb27-H2, LOW PSII accumulation 19 protein, LPA19, Thylakoid lumenal protein PSB27-H2.
What is the protein family that this protein belongs to?
Belongs to the Psb27 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen. Note=Associated with PSII on the lumenal side of the thylakoid membrane.
Protein: IOVO_FRAFR
Sequence: VSVDCSGYPKPECTAEETPLCGSDNKTYRNKCNFCNAVVESNGTLTLRHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3B_DEBHA
Sequence: MNDNMSEQEYRSLEKEVQLDDLDFSDLEAKYAVNSDFGMDNYVVVDGAPIAPEAKVPILIKVLKKLFNTVGEVVEGDEGIHMPLQDGKSKGYLFVQFKTPQMAEAAIQQLHGKKLDQKHRLLVNKLSDIEKFGAEGNVEIDFHEPEIPPFKSHGYLRSWLQDEQGRDQMALHFSETVGVYYNKKKNDPEPVIEPRKGFTSKYAKFSPLGTYLFSVHPQGVQSWGGDGFQSITKFIHNQVRLIDFSPNEKYMVTLSPLPIALPDDPAERSIFPFGPESNGHKLVIWDMATGEPARTFALPPHLEGQKDMPWPLVKWSHDDKYCARQGPGALAIYETPSFQLLDKKLVKVDDVVDFEWAPAAVHLSDSKVKEGEYILSYWTPESSNQTARVALMQIPSRKVIRTINLFQVSDCKMHWHGEGKFLCVKVDRHTKSRKTFFSNLEFFKVTEKDIPVEKLELKDVVFNFAWEPRSERFITISRLDDGNQNPSIAKNTISFYAPQVSSKGRVTSSKYTCFKEIHDKHSNTVCWSPKGRFVVVATISKSSGELEFYDCSYEEDKPANSKVNGNVKLLKAEKYSGMTNLAWDPSGRFVAAWSSSWAHSIENGYRLFEFTGNMLKDNSIDHFKEFIWRPRPASLLNAADRKKVRKNLREYSAQFDEADAMEADAASREAILLRRKLLEQWRSYRAKHAANGSKKNEVQAEIIEEIKEEIIEEKEEVVE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3 p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKT24_MESMA
Sequence: QKDCSLPVDTGRGKGWFLRYYYNKNSKTCESFIYGGVGGNKNNFLNIENCCKICKAKNC
What is the function of this protein?
Dual-function toxin that completely inhibits trypsin activity at a molar ratio of 1:1 (dissociation constant of 136 nM) and that inhibits mKv1. 3/KCNA3 potassium channel currents with an IC(50) of 129. 7 nM.
What are the official names of this protein?
Kunitz-type serine protease inhibitor BmKTT-1, Delta-KTx 2.4.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Scorpion delta-Ktx subfamily. Delta-Ktx 2 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MBTP1_CRIGR
Sequence: MKLINIWLLLLVVLLCGKKHLGDRLGKKAFEKASCPSCSHLTLKVEFSSTVVEYEYIVAFNGYFTAKARNSFISSALKSSEVDNWRIIPRNNPSSDYPSDFEVIQIKEKQKAGLLTLEDHPNIKRVTPQRKVFRSLKFAESDPIVPCNETRWSQKWQSSRPLRRASLSLGSGFWHATGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFKNVKERTNWTNERTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKKIDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDVIGVGGIDFEDNIARFSSRGMTTWELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQKRELVNPASVKQALIASARRLPGVNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETEAKNGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFALANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVALAFFVVQISKAKSRPKRRRPRAKRPQLTQQTHPPRTPSV
What is the function of this protein?
Serine protease that cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4: known substrates include SREBF1/SREBP1, SREBF2/SREBP2, BDNF, GNPTAB, ATF6, ATF6B and FAM20C (PubMed:9809072, PubMed:11163209).  Cleaves substrates after Arg-Ser-Val-Leu (SREBP2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu (PubMed:9809072, PubMed:11163209).  Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:9809072).  Also mediates the first step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B) (PubMed:11163209).  Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes (By similarity).  Cleaves the propeptide from FAM20C which is required for FAM20C secretion from the Golgi apparatus membrane and for enhancement of FAM20C kinase activity, promoting osteoblast differentiation and biomineralization (By similarity).  Involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes (By similarity).  It is required for the activation of CREB3L2/BBF2H7, a transcriptional activator of MIA3/TANGO and other genes controlling mega vesicle formation (By similarity).  Therefore, it plays a key role in the regulation of mega vesicle-mediated collagen trafficking (By similarity).
What are the official names of this protein?
Membrane-bound transcription factor site-1 protease, Endopeptidase S1P, Sterol-regulated luminal protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=May sort to other organelles, including lysosomal and/or endosomal compartments.
Protein: MNTH_YERPP
Sequence: MLNGRAVDTSRRPLRKIKLSLMGPAFIAAIAYIDPGNFATNIQAGATFGYTLLWVVVWANVMAMLVQLLSAKLGIATGKNLAEHIRDRFPRPVVWAYWVQAEIIVMATDLAEFIGAAIGFKLLFGVTLLQGAVLTGIATFLILMLQNRGQKPLELVIGGLLLFVAAAYIVELIFSQPDIAALGRGMLIPNLPDGNAVFLAAGVLGATIMPHVIYLHSALTQTGGEESKTERYASTKFDVAIAMTIAGFVNLAMMATAAAAFHFNGYENIAEIEEAYITLQPLLGNAAATVFGLSLIAAGLSSTVVGTLAGQVVMQGFVRFYIPMWVRRIVTMLPSFIVILAGMDATQILVMSQVLLSFGIALALVPLLVFTGNKELMGELVDTKTTQILGKLVVLIVVGLNAYLLISLL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM1_SULNB
Sequence: MYYQIVSFSHKNCEQSMREKLAFPNDEEKATFLEQLTGFEFVHEAFIISTCNRVEIVMATRDNFSSYHAVLGLMSQKGGLNFYELKSTAKRYDDEEAIEHIFSVVSSLDSLVIGESQITGQVKEAFRFSFQHGTAGRRLNRVLSYAVKCAAEVRNATNISQNPISIASVAVAQAHKLLGDNIQGMKGIVVGAGDMGVLAAKHLLRVGCDVVLIGRDLDKVQTVADSLGEDVKADTMENLTKYINRYRLLFSATSSPEPVITGDLIENETLPRQWFDMAIPRDIEDMELEKLQLFRIDDLRAISNDNHAMREEQAVRANEIVERYTEEFYAWLKALSIEPVIKQMRQHVSAAIEKEMQRALKKGFVPKEYESNMRKMAEQMFNRFLHDPTQNLRASSTESKNTNCIESVKKMFNIDTEHVDFKQYKNDHHTKGYSA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SYM_ERWT9
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADIWVRYQRMRGNQVYFICADDAHGTPIMLKAQQMGVAPEQMIADMSQEHQTDFAGFNISYDNYHSTHSEENRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPNCKSPDQYGDNCEVCSATYSPTELIEPKSVVSGATPVLRDSEHFFFDLPEFSAMLQAWTRSGALQEQVANKMQEWFDSGLQQWDISRDAPYFGFEIPGAPGKYFYVWLDAPIGYMGSFKNLCDKRGDIDFDAFWQKDSDAELYHFIGKDIVYFHSLFWPAMLEGSQFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLQHLDADSLRYYYAAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFAGQLSAELADPALYQTFIDASTSIAQAWSSREFSRAVREIMALADAANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTWLKPVMPSLAERAEAFLNQPLTWDGIEQPLLNHNIAAFKALYNRIEMDKVNGLIAASKEDTAAAQPAVTGPLADDPLQETISFDDFAKVDMRIALIENAELVDGSDKLLRLTLDIGGEKRNVFSGIRAAYPDPALLVGRLTVMVANLAPRKMRFGLSEGMVMAAGPGGKDIFLLSPDSGAQPGQQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_BACTN
Sequence: MAQKLWEKSVQVNKDIERFTVGRDREMDLYLAKHDVLGSMAHITMLESIGLLTKEELEQLLAELKTIYASVERGEFIIEEGVEDVHSQVELMLTRRLGDVGKKIHSGRSRNDQVLLDLKLFTRTQIREIAEAVEQLFHVLILQSERYKNVLMPGYTHLQIAMPSSFGLWFGAYAESLVDDMQFLQAAFRMCNRNPLGSAAGYGSSFPLNRTMTTDLLGFDSLNYNVVYAQMGRGKLERNVAFALATIAGTISKLAFDACMFNSQNFGFVKLPDDCTTGSSIMPHKKNPDVFELTRAKCNKLQSLPQQIMMIANNLPSGYFRDLQIIKEVFLPAFQELKDCLQMTTYIMNEIKVNEHILDDDKYLFIFSVEEVNRLAREGMPFRDAYKKVGLDIEAGKFTHDKQVHHTHEGSIGNLCNDEISALMQQVVDGFNFCGMEQAEKALLGR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_CHLAD
Sequence: MKASELRALDDAQLRAKLSEYKVELFNLRFQKATGKLTNTARPKQVKKDIARILTILRERELAQAELG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: AER4_AERHY
Sequence: MKKLKITGLSLIISGLLMAQAQAAEPVYPDQLRLFSLGQEVCGDKYRPVNREEAQSIKSNIVGMMGQWQISGLANGWVIMGPGYNGEIKPGSASSTWCYPTNPATGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAHYLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDGYRCGDKTSIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVVGWAINDSDTPQSGYDVTLRYDTATNWSKTNTYGLSEKVTTKNKFKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPTVPAHSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRWGGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYIPGEVKWWDWNWTIQQNGLPTMQNNLAKVLRPVRAGITGDFSAESQFAGNIEIGAPVPVAAASHSSRARNLSAGQGLRLEIPLDAQELSGLGFNNVSLSVTPAANQ
What is the function of this protein?
Secreted, cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and cell death.  The pores are formed by transmembrane beta-strands and are approximately 3 nm in diameter.
What are the official names of this protein?
Aerolysin-4, Hemolysin-4.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=Secreted as a soluble precursor.
Protein: NDBO_LYCMC
Sequence: MISRFCLLFLLVFVVSKIQAVEDFNEENEVDDLDDLDFLDDLDLDLSPEELEYLENWAKEFED
What are the official names of this protein?
Anionic peptide 10.1.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: XGEA_ASPAC
Sequence: MKLSLLSLATLASAASLQRRSDFCGQWDTATAGDFTLYNDLWGESAGTGSQCTGVDSYSGDTIAWHTSWSWSGGSSSVKSYVNAALTFTPTQLNCISSIPTTWKWSYSGSSIVADVAYDTFLAETASGSSKYEIMVWLAALGGAGPISSTGSTIATPTIAGVNWKLYSGPNGDTTVYSFVADSTTESFSGDLNDFFTYLVDNEGVSDELYLTTLEAGTEPFTGSNAKLTVSEYSISIE
What is the function of this protein?
Catalyzes endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan with retention of the beta-configuration of the glycosyl residues.  Specific for xyloglucan and does not hydrolyze other cell wall components.
What are the official names of this protein?
Xyloglucan-specific endo-beta-1,4-glucanase A, Xyloglucanase A, Xyloglucanendohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 12 (cellulase H) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMM_CAMLR
Sequence: MKLFGTDGVRGKAGEFLDSFLAMRLAMAAGIYFKDKALTNNILVGKDTRRSGYMIENAIVSGLTSIGYNVIEIGPMPTPAIAFLTEDMRCDAGIMISASHNPYYDNGIKFFDAHGNKLDEQAEAKIEEIYFNDKLIEEARTTKSQIGQAKRIDDVIGRYIVSIKNSFPKELTLKSLRVVLDVAHGASYKVAPTVFRELGADVIVINDKPNGLNINENCGALHPLNLALEVKKFRADVGFAFDGDADRLVVVDEKGEVAHGDSLLGVLALFLKKQGKLKSSVVSTIMSNGALKEFLTKYKIPHETCNVGDKYVLEKLKECGGNFGGEQSGHIIFSDYAKTGDGLVAALQFSALMLSEAKSASEILNQVKPYPQLLHNLKISEKKDLSKLAGLEELKKDLEKKGIASLFRYSGTENLIRLLLEAKDIKLLEKEMKVVESFFMKVLNA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MERA_SHEPU
Sequence: MILLSIEGMTCPSCVAHVKEALDAIEGVNKVEISYENARATITTNGGVSVTVLIGAIEALGYIAKESTGTAKEITSPNDCCDNENASNTESNQTQHVAIIGTGSGAFACAIKAAEGGAKVTLIEGADVIGGCCVNVGCVPSKILIRAAQLAQQQRNNPFTGLENHAPQLSRALLTQQQTARVEELRAAKYQNILETNPALSLLKGWAQFKNANTLIVRKNDGTEQAVHADKILIATGSTPTIPPIDGLTETPYWTSTEALFAQELPQHLVVIGSSVVALEIAQAYRRLGSEVTILARHTLLYREDPLLGEKLTGCFEKEGIRVLNSTQATKVTHDGSQFTLETNAGDLRCDRLLVSTGRHANTCQLNLGAVGVTTNKKGEIVVNERMETNVPGIYAAGDCCNMPQFVYVAAAAGSRSGINMTGGYAKLDLSTMPAVIFTDPQVATVGLTEEQANAQDIETDSRVLEMENVPRALANFETDGFIKLVTEKATGRLIGAQILAHEGGELIQSAALAIRNRMTVTELADQLFPYLTMVEGLKLCAQTFNKDVKELSCCAG
What is the function of this protein?
Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase.  MerA protein is responsible for volatilizing mercury as Hg(0).
What are the official names of this protein?
Mercuric reductase, Hg(II) reductase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: RS10_SODGM
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DNLI_NITMS
Sequence: MEFSILADSFNKMESTRKRLELTQYLVELFKKTPQEVISKIVYLLQGKLRPDFEGVELGVAEKLAIRAISKSSGIPIKKIEEEYRKGGDLGHAATTILEQKTQTTFLVEDITVERVYETLFKIAKLEGNRSQDMKMKYISSLLNDASPLEASFILKILLGTLRLGIAENTVMDALALAFSGNKENRKILEHAYNVSSDLGKVAEVLATEGLAEVEKFKIILFNPIRPMLADRVKSEQEAIEKMGNEFAAEYKLDGERVQLHIEGDKVVLFSRSLENISSYYPDIIEKIPKTIQAENIVLEAEAVAINENTGEFLPFQELMHRRRKYKIEKAVTQYPITVNLFDILYCNGKSCLELDYKERREKMEKVVKEDDFVKHIPMAIVKNENDIEDFFENSINAGSEGLMLKTLVSPYQAGSRGSHWLKLKREYQNELGDSLDLVVIGGFFGKGRRTGNYGTLLLATYEEDEDTFTSICKVGTGFSDEDLDQLYQILNPKVTIKKNPRINSEMEADVWFEPELVIEVVASEITLSPIHKAARDKIRKGAGLALRFPKFTGKMRVEKMAEDASTNEEVITLYQGQKKVAHDKSLM
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: URE1_BURP6
Sequence: MTLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQLPAADVADTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTGPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDTDTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTNPTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALTGDGARNDNFRAKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIIKGGMIAVAQMGDPNASIPTPQPVHYREMFATRGGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPETYDVVADGALLTCEPAAVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_STRZP
Sequence: MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFEGVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: Y2186_OCEIH
Sequence: MKVSYHGHSVVQVETETHKIVIDPFINGNDACDLNASTLETDVILLTHAHNDHVGDTFEIAKNNDAFIVAPNELANYLSAQGLNAHPMHIGGSRKFDFGTVKLTQAFHGSSYVAEDGSVIYGGMPAGILLTIDGKTIYHVGDTALFTDLKMYGEMHDIDIAFIPIGDNFTMGPEDAVYAADWINANISVPVHYNTFPVIEQDAKAWANQIKTGKGYAMNIGEVIDL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase OB2186.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: ETK_ECO27
Sequence: MTTKNMNTPPGSTQENEIDLLRLVGELWDHRKFIISVTALFTLIAVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMIPNSSPESAPEIQLLQSRMILGKTIAELNLRDIVEQKYFPIVGRGWARLTKEKPGELAISWMHIPQLNGQDQQLTLTVGENGHYTLEGEGFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQGTFTVSERSKESGMLELTMTGDDPQLITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQLPEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQLNELTFREAEISQLYKKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNRQQELSISKSSAIGNVRIIDPAVTQPQPVKPKKALNVVLGFILGLFISVGAVLARAMLRRGVEAPEQLEEHGISVYATIPMSEWLDKRTRLRKKNLFSNQQRHRTKNIPFLAVDNPADSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQSDQKVLFIDADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSELLMRDRMRQLLEWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVSLSMQRLEQAGVNIKGAILNGVIKRASTAYSYGYNYYGYSYSEKE
What are the official names of this protein?
Tyrosine-protein kinase etk.
What is the protein family that this protein belongs to?
Belongs to the etk/wzc family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MHPD_BURVG
Sequence: MSDDNSIASMAARLREAQASGRTIAPLRDTCPGGDATLAYAIQQINNDLRKTNGERVVGRKIGLTSPAVQKQLGVDQPDFGALFASMAYGDGEPMPLASLIQPKVEAEIALVLERDLTAEKHTFADLISATAYAVAAIEVVDSRIRDWDIRFFDTVADNASSALFVLGSRPVLLRDIDLTACAMTLAQDGEVLSRGNGAACLGNPLNAAAWLADRMVRLGTPLRAGDVVLTGALGPMVAVKAAGTYAAHIDGLGSVRATFTE
What is the function of this protein?
Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.
What are the official names of this protein?
2-keto-4-pentenoate hydratase, 2-hydroxypentadienoic acid hydratase.
What is the protein family that this protein belongs to?
Belongs to the hydratase/decarboxylase family. MhpD subfamily.
Protein: RL2_LISMO
Sequence: MAIKKYKPTTNGRRHMTSSDFAEITTSTPEKSLLRPLKKKAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGIPGRVATIEYDPNRSANIALINYADGEKRYIIAAKGLEVGQTIYSGAEADIKVGNALELKDIPVGTVIHNIEMKPGKGGQLVRSAGTSAQVLGKEGKYVLIRLNSGEVRMILATCRATIGQVGNEQHELINIGKAGRSRWMGKRPTVRGSVMNPNDHPHGGGEGKAPIGRKSPMSPWGKPTLGYKTRKKNNNSDKFIVRRRKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SMP1_YEAST
Sequence: MGRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEYSSVDMSNLLNVHQNNTDLPHNIIEPSDYGDYVKKPRVVLNERKRRRRRATVLQPASHSGSCTVSSQDSSSVQNNGNLSAPLASNDAGNAGVSTPLVHCHGAISRSGSNHSDCARNSADYQMLQGGLNSGGSFHANDYKESVDQQHVANEAIHRNFMNKRIRPDTHLLLSESNHSNYHNFYPSPYENLPKPSLPASLVGNIPSFQSQFVQVIPANSNPMGKGFNGTGDSESFEAKQKIHPTVAISNTLEGPAPVQAMVHHLHQLNSNRGKLSGKPYLKLNIPKATNDACQRSPAMYSGTASPKTDVQATPNQMLASNMSSPLSRSKFLGFKNNDMDDLYHNGRCGSTYVNNKTFFLKPPIGRPPKFPKSPSSSIVVFPSSVASSTLKSTSSTNSPD
What is the function of this protein?
Transcription factor that controls part of the HOG1-mediated osmostress responses.  Binds to the DNA sequence 5'-ACTACTA[TA](4)TAG-3'.  Does not appear to function in the MPK1 pathway.
What are the official names of this protein?
Transcription factor SMP1.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL16_STRU0
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVSPVKRGKVMFEIAGVSEEVAREAFRLAGHKLPVKVKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.