PharMolix/UniProtQA huggingface dataset:
Protein: PPIL1_MOUSE
Sequence: MAAIPPDTWQPPNVYLETSMGVIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKILKAYPSG
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:33220177).  PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Catalyzes prolyl peptide bond isomerization in CDC40/PRP17 (By similarity).  Plays an important role in embryonic brain development; this function is independent of its isomerase activity (PubMed:33220177).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 1, PPIase, Rotamase PPIL1.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_SACS2
Sequence: MVELLGIIRIRGWAKAPWYINETLNMLRLRYNFNTMVYPKTSQILGMLNKVSPYITWGEIDPDTLKLLIINRLETVKGDKVSDSYVKEVLKIENIDAMVKQLYEGKIYLHKLDEYFKLPIRLHPPRGGFKGSVKRPYKNKGEFGYRGDKINELMRRMV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RECF_PSEFS
Sequence: MSLSRVSVTAVRNLHPVTFSPSPRINILHGANGSGKTSVLEAIHLLGLARSFRSARLLPVIQYEQLACTVFGQVELAEGGHSSLGISRDRGGEFQIRIDGQNARSAAQLAEILPLQLINPDSFRLLEGAPKIRRQFLDWGVFHVEPRFMATWQRLQKALRQRNSWLRHGTLDAASQAAWDRELCLASDEIDEYRRAYIKALKPVFEQTLSELLDLEGLTLSYYRGWDKERELSAVLATSLQRDQQIGHTQAGPQRADLRLRLGAHNAADILSRGQQKLVVCALRIAQGHLVSQARRGQCIYLVDDLPSELDEQHRRALCRLLEELRCQVFITCVDHELLREGWQTETPVALFHVEQGRITQTHDHRE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_STRAW
Sequence: MTYPGPPRPAHVSATPLAELAGQMGAATPERDAEVTGITHDSRAVRPGDLYAALPGARLHGADFVTQAAGLGAVAVLTDPTGADRAAATGLPVLVVDDPRGRMGELAATIYGHPGRDLLQIGITGTSGKTTTAYLIEGGLRTVRSTGLIGTVEMRIGDERIKSERTTPEATDLQALFAVMRERGVDAVAMEVSSHALVLGRVDGCVFDIAVFNNLSPEHMEFHSDMEDYFRAKAQLFTPQRSKLGVVNFDDEYGRRLVEEAGVPIVTFSAEGHPDADWRAQDVEVGPMDSTFTVIGPKEERITARSPLAGPFNVANTLAAIVALAAAGLDPQAAADGIAAVPGVPGRLERVDVGQPYLAVVDYAHKTDAVESVLRALRKVTEGKLHIVLGCGGDRDRTKRMPMGAAAARLADTAVLTSDNPRSEDPLAILATMLAGAAEVPSHERGEVQVFENRAAAIAAVVARARPGDTVLVAGKGHEQGQDIAGVVRPFDDRLVLREAIQQTQG
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHAC2_PSEOL
Sequence: MKDKPAKGTPTLPATSMNVQNAILGLRGRDLISTLRNVSRQSLRHPLHTAHHLLALGGQLGRVILGDTPLQPNPRDPRFSDPTWSQNPFYRRGLQAYLAWQKQTRLWIEESHLDDDDRARAHFLFNLINDALAPSNSLLNPLAVKELFNSGGQSLVRGVAHLLDDLRHNDGLPRQVDERAFEVGGNLAATAGAVVFRNELLELIQYKPMSEKQHARPLLVVPPQINKFYIFDLSSTNSFVQYMLKNGLQVFMVSWRNPDPRHREWGLSSYVQALEEALNACRSISGNRDPNLMGACAGGLTMAALQGHLQAKHQLRRVRSATYLVSLLDSKFESPASLFADEQTIEAAKRRSYQRGVLDGAEVARIFAWMRPNDLIWNYWVNNYLLGKTPPAFDILYWNADSTRLPAALHGDLLDFFKLNPLTHPAGLEVCGTPIDLQKVELDSFTVAGSNDHITPWDAVYRSALLLGGDRRFVLANSGHIQSIINPPGNPKAYYLANPKLSSDPRAWLHDAKRSEGSWWPLWLEWITARSGPLKAPRSELGNATYPPLGPAPGTYVLTR
What is the function of this protein?
Synthesizes poly(3-hydroxyalkanoates) (PHA), complements a mutant of P. putida that does not make PHA.
What are the official names of this protein?
Poly(3-hydroxyalkanoate) polymerase 2, PHA polymerase 2, ORF3, PHA synthase 2, Polyhydroxyalkanoic acid synthase 2.
What is the protein family that this protein belongs to?
Belongs to the PHA/PHB synthase family. Type II PhaC subfamily.
Protein: YB63_SCHPO
Sequence: MAPSVATSLKAEILPSPRTSSPSSNFKTCVSNENGCINCRCSPSEPHESANVDESVNKLSKTFSKLSLNPTFQALNMDLGLLHENITLDRIPKVPENHVSLIDIDEARAKEDPNFQIHSTPSRMPPHYVQPHPPFSVFPAPILDVRELTKPGAVKRVFHFELDVSNYPLPEGEEWMVGGSFGVMAPNNEEDVDELLQLLHINPDQADAPVLLKTDGGRWPTIWAEDTPRELVTTRRELLKWTVEFMSVAPKKQLIRLLAEYAKDDTERQVLLFLVSRLGQRAFCDLRDHNVTLITLLKAFPSVQLPLDHLLTVLPQLMPRWYSLSNDPKVSNNVLEFAVTVVEINKVEGGTRSGIGSGFLKRLALRFLNGERDLVLPMYRGLHKNAFATHFASDGPMCLIGAGVGVAPFRGFVQRRLTNATCAGKVWVFHGCRDQELDELYHGEWENPLQKSSDDDASSTVSQQTETEMDSFEVKKDGTSGPNHLVVESRSHQHAYVQDEIRHRGDIVWSVLSHPHGKVYLCGGKKGFLDGVENALIDVCVQYGKMSRLEATQQLALWQSPLNLKYIKEIW
What are the official names of this protein?
Uncharacterized FAD-binding protein C12C2.03c.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: NUP93_PONAB
Sequence: MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLCSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDNIEMAYARQIYIYNEKIVNGHLQPNLVDLCASVAELDDKSISDMWTMVKQMTDVLLTPATDALKNRSSVEVRMEFVRQALAYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPLPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVNRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIERLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSSSRPQRVIEDRDSQLRSQACTLITFAGMIPYRTSGDTNARLVQMEVLMN
What is the function of this protein?
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.  May anchor nucleoporins, but not NUP153 and TPR, to the NPC.  During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.
What are the official names of this protein?
Nuclear pore complex protein Nup93, 93 kDa nucleoporin, Nucleoporin Nup93.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin interacting component (NIC) family.
What are the subcellular locations of this protein?
Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Nucleus envelope. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore.
Protein: RS3_CAMJ8
Sequence: MGQKVNPIGLRLGINRNWESRWFPTKANLVENIGEDYKIRAFLKRKLYYAGISQILVERTAKKLRVTVVAARPGIIIGKKGSDVDNLRKELQDLIGKDVNINIKEERKAGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKAGAKGIKVSVSGRLGGAEMARTEWYLEGRVPLHTLRAKIDYGFAEARTTYGNIGVKVWIFKGEVLHKGMQPEKTEESAPAKKPRRTRRGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TIPRL_CAEEL
Sequence: MSDRRSIDEVMVRAAKNAKREEKFDLGFFKFISLAGHILESSCKHSEDQEDPSCLKCKYDRELKLEERPEMVFARNSLTIQFGRLGSIEFNALDALKMVCADRLPDVKVGASTVWQSARQDRIQQISEHQKPFDWTYTTHYKGTVTGCQVTPTTERIDMERLKRRDEILFSSSITLFEDELADHGIAQLLARVRVMRGYFFVLLRFYMRVDNVLLRVCDTRIVGNEFDGHVIREWQLREAKYGNLGHVDPEELLDVDRAWMHLPVVEEHFDRVSVDRERLF
What are the official names of this protein?
TIP41-like protein.
What is the protein family that this protein belongs to?
Belongs to the TIP41 family.
Protein: TTCA_NITOC
Sequence: MNKQSRKAQYNANKLQKRLRRLVGQAIETFNMIEDGDRLMVCLSGGKDSYALLDILLSLQKHAPVKFDLIAVNLDQKQPGFPEHVLPHYLESLGVSYRIVEQDTYSVVKRVIPEGKTTCSLCSRLRRGILYGTAEELGATKIALGHHRDDILETFFLNMFHGGTLKGMPPKLLSDNGRHIVIRPLAYCREKDLETYAHLKAFPIIPCNLCGSQANLQRQAIKAMMKAWDKQFPGRLETMFRALQNVKPSHLADSTLYNFQGLQKQESPFPEGDKAFDEEVFLESQEKSPPFHGSKIRVLQFK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_STRPD
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAVAETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIAYLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL766_MIMIV
Sequence: MTYQTFFLISDPDNLDYPIYIVYDKSRVLDYFGDIFYTQSTTITEIELGDTNPDFKISILHNNNYLTSHVIKSTKYSLLDVNTVQMLLDYKDPDYELKSTCHLYIFYMTKNRFDICDYLIASNIKYIDSFGNISLLNSTNLNNYQLIKYIIDNNEFFNCRYYYLMLGILRYTKFYDLVDYILELISKSNNHIDYNSLLMELFSKFDCMGSLINSEIDAFQIKKLIDGNYFDEKVLFDTVICNNFELTKYLVEKGFNYDFDTIINSNVKFDVLKYFIELGNYLTDDHIYMILCNTSCEYYEKIIYLVDNNHITEKYFTKSIISRIIHFEFYLLDYLTNKLNIIELIDLDLLMKTSIRCNETVMVKKCIDYGINPDEYMEFAIKHDICIAKKLMELGGNIPDNMCIYNPDAYLTIESIDIILENNYDSLENLLPKIINNCDSEIIMYIIKKLTDTTIIIPHGLIKIFIRSYYWGRGNDIYSGIINSNLNFDDYQQIIIGIMRKEYNKIEQLIFSSTYYNSIELLFVVTLSENIELFKLLLEINCNDNNYLSWAFVFSIGCFKLMKYIVDNYNIDIYQRQFEVCIMSLQNYYRCYNQSDQIKFYLLLMGYEISCFNNKKNYNENIPLVKFMREMGVTLV
What are the official names of this protein?
Putative ankyrin repeat protein L766.
Protein: RBL_PROM5
Sequence: MSKKYDAGVKEYRDTYWTPEYVPLDTDLLACFKCTGQEGVPREEVAAAVAAESSTGTWSTVWSELLTDLEFYKGRCYRIEDVPGDPEAFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPIAFIKTCGGPPNGIVVERDRLNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDLTKDDENINSQPFQRWRERFEFVAEAVKLAQQETGEVKGHYLNCTANTPEELYERAEFAKELDMPIIMHDYITGGFTANTGLANWCRKNGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDNLRESFVPEDRSRGNFFDQDWGSMPGVFAVASGGIHVWHMPALLAIFGDDSCLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILMEAAKHSPELAIALETWKEIKFEFDTVDKLDVQG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: RL27_GEMAT
Sequence: MAHKKGVGSSRNGRDSNPKYRGIKKYGGEFVTAGNIILRQCGTKWHPGSNVGMGTDYTIYSLVDGVVQFAHKSKKAYKVNVVPVEYVEVEIEEVVEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: IDI_SALA4
Sequence: MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDGQLLVTRRSLSKKAWPGVWTNSVCGHPQQGETTEEAIIRRCRFELGVEITDLTPVYPHFSYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWKSLLATPWAFSPWMVMQASDEQARERLLDYCQR
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSXB_BACSU
Sequence: MIQATIRRSHDKGILSFEMTGHANFAEHGQDLVCAGVTAVVFGAVNAVIVLAGFEPLLDIGEDGGYFYFEFPESLDPEARQKAQLLIEGMIVSLETIERDYKDNLRVTTNII
What are the official names of this protein?
Uncharacterized protein YsxB.
What is the protein family that this protein belongs to?
To M.genitalium MG233.
Protein: CUT2_CAEEL
Sequence: MQKLIVFFTTIAAAQAFLLPSGGGGGCGCAPPPPPPPCGCGAPALPPLQLPRFELPRLSLPSLGGGCGGPAPCAAAPIAAPAGGYATAPAAPVGGYATGPAFGGAAPIGGAYQAAPAFVGAAPVGGAYQSGPAFGGAAPAGGAYQSGPAFGGAAPAGGAYQSGPAFGGAAPAVGGAYQAGQAAVESAPLGGAAPAGGYQASAPAAVEAAPAAGGYQAAAPAGGAYAGHKKN
What is the function of this protein?
Component of the insoluble part of the cuticles.
What are the official names of this protein?
Cuticlin 2.
What are the subcellular locations of this protein?
Secreted.
Protein: NU2C2_SOLBU
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDSLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ISPE_GEOUR
Sequence: MKKVKLKAPAKVNYRLDVLRRRPDGYHDLRMIMQRIDLCDDIEIALSGTRGVRVTCGRDGVPDGPDNIAWRAADALLTISGRAVGLDIAITKNIPVAAGLGGGSSDGATVLMGVNELLGLGFSDERLMEIGVKLGADVPFFIFKKTALAEGIGDKLTAVETISPVWLVLVNPHLHVSTGWVYQNLRLTAMKDDDIIPRFYGKIEDVCAILANDLESVTIGRFPVIQEIKERLLRVGACGSLMSGSGSTVFGLFKDEAAARRAAETLAAESNWFVVAVKTL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CYSD_PECAS
Sequence: MDEKRLTHLRQLEAESIHIIREVAAEFGNPVMMYSIGKDSSVMLHLARKAFYPGSLPFPLLHVDTGWKFREMYEFRDHTAKAYGCELLVHRNPQGEALGINPFVHGSAKHTDIMKTEGLKQALDKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTELDIWQYIYLENIDIVPLYLAAPRPVVERDGMLLMVDDDRIDLQPGEVIEQRMVRFRTLGCWPLTGAVASHAQTLPEIIEEMLVSTTSERQGRVIDRDQSGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RK23_CHLVU
Sequence: MMLDLVKYPVIRTEKTTRLVENNQLSFDVDVRITKPQIRKIIEEFFNVKVLAVNTHRPPRKTNRLGSKPSYKRVIVTVDSDVTLLK
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SPAC_BPT4
Sequence: MKKFIFATIFALASCAAQPAMAGYDKDLCEWSMTADQTEVETQIEADIMNIVKRDRPEMKAEVQKQLKSGGVMQYNYVLYCDKNFNNKNIIAEVVGE
What is the function of this protein?
Inhibits viral DNA ejection into the host cytoplasm, thereby confering the infected host bacteria with immunity against secondary phage infection (PubMed:4589853).  Achieves superinfection exclusion by localizing to the periplasm and inhibiting the activity of tail-associated lysozyme, thereby preventing penetration by the tail tube of incoming phages (PubMed:32987925, PubMed:33214665).
What are the official names of this protein?
Protein spackle.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae spackle protein family.
What are the subcellular locations of this protein?
Host periplasm.
Protein: PSTB3_STRA3
Sequence: MSRTVSKLVINNLDLYYGEFHALKDVNLDIEEKEITAFIGPSGCGKSTLLKSINRMNDLVKNCKITGDITLEGEDVYRQLDINQLRKKVGMVFQKPNPFPMSIYDNVAFGPRTHGIHSKAELDDIVERSLKQAALWDEVKDRLHKSALGMSGGQQQRLCIARALAIEPDVLLMDEPTSALDPISTAKIEELVIQLKKNYTIVIVTHNMQQAVRISDKTAFFLMGEVVEYNKTSQLFSLPQDERTENYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 3, ABC phosphate transporter 3, Phosphate-transporting ATPase 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NADK_DECAR
Sequence: MQEFDPMNRGFASYRSPRTIALVGKYHSLEIAESLRRLAEYLYERGVSVFIERETAEHIGKIVDLSRWVTCGFNDIGAHADLAIVLGGDGTMLNAARRLARYCVPLVGVNQGRLGFMTDIARDDMLTCMDDLLDGRFAPENRMLLAAEVTRDGKEVASNMALNDVVVDKGAIGRMIEFELFIDGEFIYNLRSDGLIVSTPTGSTAYSMSAGGPILNPTLTGIALVPLCPHALSNRPIIVNDNTDIELRIVNADDPRVHFDGQVTLDLERGDCVRLRRSEHTICFLHPPGYSYFAMLRQKLQWSERPKGP
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PULA_STRP2
Sequence: MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISSDESTPTTNEPNNRNTTTLAQPLTDTAADSGKNESDISSPRNANASLEKTEEKPATEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN
What is the function of this protein?
Virulence factor (PubMed:17041037).  Involved in the degradation of glycogen of the mammalian host cells.  Hydrolyzes the alpha-1,6-branchpoints of glycogen.  Hydrolyzes pullulan.  Does not hydrolyze dextran.  Binds to mouse lung alveolar type II cells that are rich in glycogen stores.  Is an alpha-glucan-specific carbohydrate-binding protein, which binds to amylose (pure alpha-(1,4)-linked glucose), amylopectin (alpha-(1,4)-linked glucose with alpha-(1,6) branch points), pullulan (linear polymer of mixed alpha-(1,4)- and alpha-(1,6)-linked glucose) and glycogen (similar to amylopectin with more frequent alpha-(1,6) branch points) in vitro.  Does not bind to dextran (a linear polymer of alpha-(1,6)-linked glucose) (By similarity).
What are the official names of this protein?
Pullulanase A, Alpha-dextrin endo-1,6-alpha-glucosidase, Pullulan 6-glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Cell surface. Note=Localizes to cytoplasm in the lung alveolar type II cells of the mouse and human hosts.
Protein: NADK_ALCBS
Sequence: MRSLVAQEKFRNIGLIARSESEQALYSLRQLIHFLHGRDCTVILDKHIIGHLPEMGLQAASASQMGEACDLVIVVGGDGSLLGAARTLARYKVPVLGVNRGHLGFLTDILPSEIESRVGQVLDGEYSTEKRFLLDLEVRRGRTVVGEGSALNDIVLLSGDSVHMIDFELMIDGHFVYGQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAMVLVPLNPHTLTSRPLVVAGDSEIKIHITTEKVRPLVSCDGTEGIRLQVDDVIAIRKKPHRLHLIHPPGHDFYQACRSKLGWSSRPGDNN
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.