PharMolix/UniProtQA huggingface dataset:
Protein: DNAA_BRUSU
Sequence: MKMDSAVSEEAFERLTAKLKARVGGEIYSSWFGRLKLDDISKSIVRLSVPTAFLRSWINNHYSELLTELWQEENPQILKVEVVVRGVSRVVRSAAPAETCDNAEAKPAVTPREKMVFPVGQSFGGQSLGEKRGSAVVAESAAATDAVLGSPLDPRYTFDTFVDGASNRVALAAARTIAEAGSSAVRFNPLFIHASVGLGKTHLLQAIAAAALQRQEKARVVYLTAEYFMWRFATAIRDNNALSFKEQLRDIDLLVIDDMQFLQGKSIQHEFCHLLNTLLDSAKQVVVAADRAPSELESLDVRVRSRLQGGVALEVAAPDYEMRLEMLRRRLASAQCEDASLDIGEEILAHVARTVTGSGRELEGAFNQLLFRQSFEPNISIDRVDELLGHLTRAGEPKRIRIEEIQRIVARHYNVSKQDLLSNRRTRTIVKPRQVAMYLAKMMTPRSLPEIGRRFGGRDHTTVLHAVRKIEDLVGADTKLAQELELLKRLINDQAA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TB1_ORYSJ
Sequence: MLPFFDSPSPMDIPLYQQLQLTPPSPKPDHHHHHHSTFFYYHHHPPPSPSFPSFPSPAAATIASPSPAMHPFMDLELEPHGQQLAAAEEDGAGGQGVDAGVPFGVDGAAAAAAARKDRHSKISTAGGMRDRRMRLSLDVARKFFALQDMLGFDKASKTVQWLLNMSKAAIREIMSDDASSVCEEDGSSSLSVDGKQQQHSNPADRGGGAGDHKGAAHGHSDGKKPAKPRRAAANPKPPRRLANAHPVPDKESRAKARERARERTKEKNRMRWVTLASAISVEAATAAAAAGEDKSPTSPSNNLNHSSSTNLVSTELEDGSSSTRHNGVGVSGGRMQEISAASEASDVIMAFANGGAYGDSGSYYLQQQHQQDQWELGGVVYANSRHYC
What is the function of this protein?
Probable transcription factor that functions as a negative regulator of lateral branching, presumably through its expression in axillary buds (PubMed:12581309, PubMed:20547591).  Involved in the fine tuning of shoot branching.  May function as an integrator of multiple signaling pathways to regulate the development of axillary buds.  Works partially downstream of strigolactones to inhibit bud outgrowth (PubMed:20547591).  Binds to MADS57 to suppress the negative regulation of D14 by MADS57 and balance the expression of D14 for tillering (PubMed:23463009).
What are the official names of this protein?
Transcription factor TB1, Protein FINE CULM 1, Protein TEOSINTE BRANCHED 1 homolog, OsTB1, TCP transcription factor 8, OsTCP8.
What are the subcellular locations of this protein?
Nucleus.
Protein: MFTR_MYCTU
Sequence: MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVGAGLDRLNQ
What is the function of this protein?
May regulate a gene cluster involved in mycofactocin expression.  Mycofactocin is a conserved polypeptide that might serve as an electron carrier.
What are the official names of this protein?
Putative mycofactocin biosynthesis transcriptional regulator MftR.
Protein: GGS1_HYPPI
Sequence: MVPNANSNTVSLQSPNAIPPRTSSTGYITPFPPAKSVLRPVPESDWLGQNNTRNRSSSTTAIPLTGMHATGPQDPARYETEDLNYTSRKTWSEQKEKVLVGPFEYLFAHPGKDFRTLMVNSFNAWLEVPQESLDVITKVVGMLHTASLLVDDVEDNSLLRRGLPVAHSIFGTAQTINSANYVYFCALQELQKLKNPEAINVYTEELLNLHRGQGMDLFWRDTLTCPTEEEYLEMVGNKTGGLFRLAIKLMQAESGTPIDCVPLVNILGIIFQIQDDYRNLSSPEYGQNKGLCEDLTEGKFSFLIIHSIRSNPSNLQLLNILKQKTTDDEVKRYAVKYMEGTGSFEYTQKVISILVDRARKMTDELDNGRGKSVGIHKILDKLVV
What is the function of this protein?
Catalyzes the trans-addition of the 3 molecules of isopentenyl diphosphate (IPP) onto dimethylallyl diphosphate (DMAPP) to form geranylgeranyl pyrophosphate (GGPP).  GGPP is a precursor for the biosynthesis of many secondary metabolites, including the indole diterpenes nodulisporic acids (NA).
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: HEMH_SALDC
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDSAYIDALAKSARESFARHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLAG1_CHICK
Sequence: MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCTQQDCTKAFVSKYKLLRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHNPNKEAFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKTHAGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPMDLLDPFTCNVSVPIKDELLPVMSLPSSELTSKPFTNTLQLNLYNTQIQSMQSSASAHQMVATSLPLGMPCPIDMESVHPSHQLSLKYPLSSTSYAVSMPEKEQPLKGEIESYLMELQSGMPSSSQDSQASSSKLGLDPQVGPLDDGSGEVSLSKGSVPISEPLNTPSLDFSQLFNFIPVNGPPYNPSVSVGNLGMSYTQEEAHSSMTQLPPQTQDPQDPSNSIGLGSLHSLSAAFTSSLSTTTTLPRFHQAFQ
What is the function of this protein?
Transcription factor and proto-oncogene whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation.
What are the official names of this protein?
Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PIGF_SERS3
Sequence: MTLTKQDAVNQMMGFFQSKTLITALSLKLFDHLRDQDRNAKQMAALLNCPLRSSEQLLIALQAMGYLEKQDGLYHLPQEHRAFLVSDEPQWLGWLGRHIDTFLYPLWGELKAAVENDTHQRQTVFGDDRSWFDILYQNPDDVTDFQEFLGKFAAPFIDGFIQDYDFSQHQAFLDIGSGIGSLPIAVANAYSGVNLAICELPQTSTFLRDKLVQQGYGQRIQVLEGDVISGDLPIGDYDLIHLGWMLHDYAPETQLIILKNIYDAMPVGGRFIASETPLNADKSGPEFTALLSLNMLVSTDGGIESSPQEYLSRFHQAGFSNARIMDISGPRTLIVGEKTTHNNGSSQC
What is the function of this protein?
Involved in the biosynthesis of 4-methoxy-2,2'-bipyrrole-5-carbaldehyde (MBC), one of the terminal products involved in the biosynthesis of the red antibiotic prodigiosin (Pig).  Catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to the hydroxyl group of 4-hydroxy-2,2'-bipyrrole-5-carbaldehyde (HBC) to yield 4-methoxy-2,2'-bipyrrole-5-carbaldehyde (MBC).
What are the official names of this protein?
S-adenosyl-L-methionine-dependent methyl transferase PigF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: MSCS_ECOLI
Sequence: MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLIIARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGAAGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADGKIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKDREMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVNFKRVKEDKAA
What is the function of this protein?
Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins.  Contributes to normal resistance to hypoosmotic shock.  Forms an ion channel of 1. 0 nanosiemens conductance with a slight preference for anions.  The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa.  The channel is characterized by short bursts of activity that last for a few seconds.
What are the official names of this protein?
Small-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 3NX2_MICMP
Sequence: LTCKTCPFTTCPNSESCPGGQSICYQRKWEEHHGERIERRCVANCPAFGSHDTSLLCCTRDNCN
What is the function of this protein?
Allosteric modulator of the GABA(A) receptor (GABR), possibly increasing receptor affinity for the agonist, thus enhancing receptor opening and macroscopic desensitization.  In vivo, intracerebroventricular injection into mice results in periods of reduced basal activity, followed by bursts of intense seizures and death.
What are the official names of this protein?
Micrurotoxin 2, MmTX2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HAP_HELPX
Sequence: NSGLVYRDMSGGINEAFSDIAGEAAEYFMRGNVDWIVGADIFKSSGGLRYFDQPSRDGRSIDHASQYYSGIDVHSSGVFNRAFYLLANKSGWNVRKGFEVFAVANQLYWTPNSTFDQGGCGVVKAAQDLNYNTADVVAAFNTVGVNASCGTTPPPVGKVLEKGKPITGLSGSRGGEDFYTFTVTNSGSVVVSISGGTGDADLYVKAGSKPTTSSWDCRPYRSGNAEQCSISAVVGTTYHVMLRGYSNYSGVTLRLD
What is the function of this protein?
May play a role in ulcer formation.  Proteolytic digestion of gastric mucus has been suggested as an important mechanism by which its pathogenicity is at least partly exerted.
What are the official names of this protein?
Zinc metalloprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RASY_DICDI
Sequence: MTTNKSNGNLVKLCIMGDGGVGKTSVTIQFISNHFVHYYDPTIEDSYRKQCLIDDQVYMLDILDTAGQDELTAMRDQWIRSCEGFILVYSVTSRSSFDQVQFFREQIIRVLDRDDVPIMMIGNKSDLDDERQVTFQEGKDLARCLGMSFMEVSAKTRLNVEEVFNETVRCVKRREESLLKKDNSKDGKGDHSKKSSIFKKLNQKVNGAKISICKMM
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
Ras-like protein rasY.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: CCA_PYRHO
Sequence: MDIEDVIAEVLQRIVPTKEEENFVSTLMEEIKEKTEETIEELNLDAKPYFVGSLAKDTYLAGDHDVDLFIAFPLDTSLEELREKGLELGKVLGERLGKYEIAYAEHPYVRAEYKGIRVDIVPCYNVKNWKDVRTAVDRSILHTHWVLENIKGKNNEVRLLKRFLKGINAYGSEIYIRGFSGYLAEILIIEFGSFLNVLEKSDFMLRKKIIDPEDWMKRESEITMKTIKREVGEDKPLIVIDPVDPRRNVAANLSWERYGLFYFKSQEFLKEPSTEFFFPRKKIGNYLSALRSRKTHLITLTFNPPKLVDDILLPQVERTAKGIKRQLELEGFKVLGYDYGREFIFLEVDRLEREGIKVKRGPLYFTQHGKRFYEKNDIVWIEGKELASEKPISTFIVDVLEEILRKGQFSAGKNIKDAIVKGDILVDFVPKELSKDAYLFLSREKFRVK
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: MYOA_PLAYO
Sequence: MAVTNEELKTAHKIVRRVSNIEAFDKSGVVFKGYQIWTNISPTIEEDPNVMFVKCVVQHGSNQDKLNVVQIDPPGSGTPYEIDVKSAWNCNSQVDPMSFGDIGLLNHTNTPCVLDFLKHRYLKNQIYTTACPLIVAINPYKDLGNTTDEWIRKYRDASDHTRLPPHIFSCAREALSNLHGVNKSQTIIVSGESGAGKTEATKQIMKYFASSKNGNMDLYIQTAIMAANPVLEAFGNAKTIRNNNSSRFGRFMQLAISHEGGIRNGSVVAFLLEKSRIITQDDNERSYHIFYQFLKGADSNMKSKFGLKGIKDYKLLNPNSPDVDGIDDVKDFQEVITSLKNMQLNDEQIEVIFSIIAGILTLGNVRIVEKTEAGLSDAAGIHNDDMETFKKACELMFLDPELVKRELLIKVTIAGGNRIEGRWNKNDAEVLKLSLCKAMYEKLFLWIIKNLNSRIEPEGGFKAFMGMLDIFGFEVFKNNSLEQLFINITNEMLQKNFVDIVFERESKLYRDEGISTAELNYTSNKEVISVLCERGKSVLSYLEDQCLAPGGSDEKFVNACVVNLKSNEKFIPAKVASNKNFIIQHTIGPIQYCSDNFLLKNKDVLRGELVEIILGSGNKVVSGLFEGQVIEKGKMAKGSLIGSQFLNQLTSLMTLINSTEPHFIRCIKPNENKKPLEWCEPKILIQLHALSILEALVLRQLGYSYRRTFDEFLYQFKFVDINTSENSSLDSREKCNKILKLSGLSDDMLKIGKTMVFLKQDGAKMLSKIQREKLVEWENCVSVIEAAIMKYKHKQNVENNVSSLMRVQAHIRKRMVA
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
What are the official names of this protein?
Myosin-A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Tightly associated with the plasma membrane.
Protein: ASSY_ALKCK
Sequence: MAKEKVVLAYSGGLDTSVAVKWLTDKGYDVIAVGLDVGEGKDLEFVKQKALQVGAIQSYTIDAKKEYAESFVLPALQAHALYEQKYPLVSALSRPLISKKLVEIAEQTGATAVAHGCTGKGNDQVRFEVSIQALNPNLKVLAPVREWAWSRDEEIEYAKAHNIPIPIDLDNPYSVDQNLWGRSNECGVLEDPWATPPEGAYALTAPLEKTPDTPDIIELSFEKGVPVAINGEAYPLDQLILTLNEIAGKHGVGRIDHVENRLVGIKSREVYECPGAMTLIKAHKELEDLTLPKELAHFKPVIEKKLTELIYEGLWFSSLQPALLAFLKESQTHVTGVVRVKLFKGHAIIEGRKSAYSLYNEKLATYTPDDEFDHSAAVGFISLWGLPTKVHSMVTKEKKEVTL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYLM_PONAB
Sequence: MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGSPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSGALSQASQSVILHSPEFEDALCALMVMAAPMAPHVTSEIWAGLALVPRKLCAHYTWDVSVLLQAWPAVDPEFLQEPEVVQMAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFPVQD
What are the official names of this protein?
Probable leucine--tRNA ligase, mitochondrial, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TCAA_STAAM
Sequence: MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNNIKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTKDNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRVSKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFILGTYRIPAMKSTENGDFAGYLKFDFRQSNSETVDVTEDFEEANITVTLKGDTKLNDSSKKVTINDREMAFSSSKTYGPYPQNKDITISASGKAKGKTFTTQTKTIKASDLKYNTEITLNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSSFYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQDRLQLIKTSEK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DUT_CORJK
Sequence: MTLKRNGNDAPLRIVRLDKELPLPRRAHPTDAGIDLYTAQDVTIAPGCRELVGTGIAIALPVGTVGLVHPRSGLALKKGLSIVNAPGTIDADYRGEIKVCLINLDPEEPIELARGERIAQLLVQEVSLCDVEEVNSVEELGVTVRGESGYGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: HYPF_METJA
Sequence: MEILFFGVKMKVRIKVKGIVQGVGFRPFVYRIAKKNNLKGYVKNMGNYVEILIEGKKEDIRNFINDLKNKKPPLSRIDKLDIEEIKGIEEFDDFYIIKSENAKDEEEGTIPADVAICDDCLKEMLDKNDRRYRYPFIACTNCGPRFTIVEKLPYDRENTSMRDFPLCEKCLEEYKNPLDRRFHAQATCCPICGPKVFLSDGKEIIAEKDEAIRETVKLLEEGHILAIKGIGGTHLACKVGEDDVVLELRKRLGRPTQPFAVMSKIEYTELFAEFDEDEKNALLSLRRPIVVLKKSQDYDKYFSKYVSNLDTIGVMFPYSGLHYLLFDKEIAYVMTSANLPGLPMVKDNDEILKKLNGIADYFLLHNRRIVNRCDDSVVKKVADRLVFLRRSRGFAPEPVKVNINNNKNILCVGAELNSTACIVKRDKFYLTQYIGNTSKYETFCYLRDAINNILRLTNTNKIDAIVCDLHPQFNSTKLAEELSEKFGAEIFRVQHHFAHAYSLLGDNNYFDDAIILSLDGVGYGLDGNIWGGEVLLFKDGKMERVGHLEEQYQLGGDLATKYPLRMLLSILYKAIGEEAFDFIKRYNFFSEKELRLLKFQLEKKLNCPITTSTGRVLDAVSALLGICFEKTYDGEPSIRLEPVANRFKGDINIEPKIKNNILNTTELIYKSYEMLLNNENKEKIAHFAHIYIADGLFEIAKKISNKFGINTIGITGGVSYNKIITERIMNNAKREGFNFIYHQRVPNGDGGISFGQGVAYILKNGY
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases.  HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
What are the official names of this protein?
Probable carbamoyltransferase HypF, Carbamoyl phosphate-converting enzyme HypF, [NiFe]-hydrogenase maturation factor HypF, Hydrogenase maturation protein HypF.
What is the protein family that this protein belongs to?
Belongs to the carbamoyltransferase HypF family.
Protein: EFTS_SALAI
Sequence: MSNFTAADVKKLRDLTGAGMMDSKKALTEAEGDFDKAIEILRVKGAKDVGKRAGRTAANGLVAHSGKALLELNCETDFVAKTDSFVALAQQLVEHGERSGVNSAEELLASKIDGKGVAELVQEQSAKIGEKLVLNRFAKLDGTVAVYLHRKAQDLPPAVGVLVQYTGKTDEAGDADARGVAMQIAAMRPQYLSRDDVPAEVVESERRIAEQTAREENKPEAALPKIVEGRVNSFFKDFVLLEQASVTDNKKPVRQVLAEAGVEITRFVRFEVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_STRPB
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERAGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAGDNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGIVSEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_METFK
Sequence: MASTIHLDVVSAEESIFSGEAEFVAAPAKLGEVGIYPNHAPLITTIKPGVLRVKVANGGEEQAIYISGGLLEVQPGVITVLADTAIRGHDLDEVKAIEAKRAAEEALRNNASGVDYARAQAELSEALAQLQTIEQLRKTTH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SSRP_STAS1
Sequence: MPKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGSANLKDSYAQVNRGEMFLNNMHIAPYEEGNRFNHDPRRSRKLLLHKREIAKLGERTREVGYSIVPLKLYLKHGHCKVLLGVARGKKKYDKRQALKEKAVQRDVAREMKARY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y345_AFV2P
Sequence: MKKMKGEKKAKREGYILLQEIPKLEYIFKNWNEFEDNFYVAEYNYNLKDFKFYMRKYITGIMRIWIYNYEIVMKRKGDEIEITLDDAKKIQCWDLMKILDQVFYPVMRFYQNTIEIEIVNNDVTYYIPIRPKEFKISLKLTENENEIKNAIANTKIKIDGKTLVIKKVGNKGKKYFMRRILRIPIYAKMMLKYRKITHVFAKMMLKKGILEQGEFRIMPLLKLEKLLYKKMNFRDIKYMKYFTMPIYRFNRDRVNLQGISYIDNFIITDYYYDGVNQIVFKLIAVDTRDPIVTTEKEVLATTLCGIDYKNNLWCVSISNLMLYWKISAVYKFMYDLDDRTKVFEY
What are the official names of this protein?
Uncharacterized protein ORF345.