PharMolix/UniProtQA huggingface dataset:
Protein: MLRV_BOVIN
Sequence: MSPKKAKKRAEGANYNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMLKEAPGPINFTVFLQMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYIKEMLTTQAERFSKEEIDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
What is the function of this protein?
Contractile protein that plays a role in heart development and function (By similarity).  Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force.  These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity).  During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).
What are the official names of this protein?
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, MLC-2, MLC-2v, Myosin light chain 2, slow skeletal/ventricular muscle isoform, MLC-2s/v.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, A band.
Protein: AGAR_STRCO
Sequence: MVNRRDLIKWSAVALGAGAGLAGPAPAAHAADLEWEQYPVPAAPGGNRSWQLLPSHSDDFNYTGKPQTFRGRWLDQHKDGWSGPANSLYSARHSWVADGNLIVEGRRAPDGRVYCGYVTSRTPVEYPLYTEVLMRVSGLKLSSNFWLLSRDDVNEIDVIECYGNESLHGKHMNTAYHIFQRNPFTELARSQKGYFADGSYGYNGETGQVFGDGAGQPLLRNGFHRYGVHWISATEFDFYFNGRLVRRLNRSNDLRDPRSRFFDQPMHLILNTESHQWRVDRGIEPTDAELADPSINNIYYRWVRTYQAV
What are the official names of this protein?
Extracellular agarase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BET1L_DANRE
Sequence: MADPWNRGHGAVDDMLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVSRMQN
What is the function of this protein?
Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex.  Required for the integrity of the Golgi complex (By similarity).
What are the official names of this protein?
BET1-like protein.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein.
Protein: CRCB_SALA4
Sequence: MLQLLLAVFIGGGTGSVARWMLSMRFNPLHQAIPIGTLTANLLGAFIIGMGFAWFNRMTHIDPMWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVLINLLGSFAMTALAFWLFSAAAAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZN638_MOUSE
Sequence: MSRPRFNPRGTFPLQRPRAPNPPGMRPPGPFVRPGSMGLPRFYPAGRARGIPHRFPGHGSYQNMGPQRMNVQVTQHRTDPRLTKEKLDFPEAQQKKGKPHGSRWDDESHITPPVEVKQSSVTQVTEQSPKVQSRYTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMRKMSRRLPNLPSHSRNKETLSNETVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVKNEFQPQQSISATVSTPNVICNSVFPGGDMFRQMDFPGESSSQSFFPVESGTKMSGLHISGQSVLEPVKSISQSISQTVSQTTSQSLNPPSMNQVPFTFELDAVLRQQERISQKSVISSADAHGGPTESKKDYQSEADLPIRSPFGIVKASWLPKFTQAGAQKMKRLPTPSMMNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNESNRKENETPRRRSHSPSPRHSRRSSSGHRIRRSRSPVRYIYRPRSRSPRICHRFISKYRSRSRSRSRSRSPYRSRNLLRRSPKSYRSASPERTSRKSVRSDRKKALEDGGQRSVHGTEVTKQKHTETVDKGLSPAQKPKLASGTKPSAKSLSSVKSDSHLGAYSAHKSENLEDDTLPEGKQESGKSALAQRKPQKDQSLSSNSILLVSELPEDGFTEEDIRKAFLPFGKISDVLLVPCRNEAYLEMELRKAVTSIMKYIETMPLVIKGKSVKVCVPGKKKPQNKEMKKKPSDIKKSSASALKKETDASKTMETVSSSSSAKSGQIKSSTVKVNKCAGKSAGSVKSVVTVAAKGKASIKTAKSGKKSLEAKKSGNIKNKDSNKPVTVPANSEIKASSEDKATGKSAEESPSGTLEATEKEPVNKESEEMSVVFISNLPNKGYSTEEIYNLAKPFGALKDILVLSSHKKAYIEINKKSADSMVKFYTCFPISMDGNQLSISMAPEHVDLKDEEALFTTLIQENDPEANIDKIYNRFVHLDNLPEDGLQCVLCVGHQFGKVDRYMFMSNKNKVILQLESPESALSMYNFLKQNPQNIGEHVLTCTLSPKTDSEVQRKNDLELGKGSTFSPDLKNSPVDESEVQTAADSSSVKPSEVEEETTSNIGTETSVHQEELGKEEPKQALCESDFAIQTLELEAQGAEVSIEIPLVASTPANIELFSENIDESALNQQMYTSDFEKEEAEVTNPETELAVSDSVFIEERNIKGIIEDSPSETEDIFSGIVQPMVDAIAEVDKHETVSEVLPSACNVTQAPGSYIEDEKVVSKKDIAEKVILDEKEEDEFNVKETRMDLQVKTEKAEKNEAIIFKEKLEKIIAAIREKPIESSVIKADPTKGLDQTSKPDETGKSSVLTVSNVYSSKSSIKATVVSSPKAKSTPSKTESHSTFPKPVLREQIKADKKVSAKEFGLLKNTRSGLAESNSKSKPTQIGVNRGCSGRISALQCKDSKVDYKDITKQSQETETKPPIMKRDDSNNKALALQNTKNSKSTTDRSSKSKEEPLFTFNLDEFVTVDEVIEEVNPSQAKQNPLKGKRKEALKISPSPELNLKKKKGKTSVPHSVEGELSFVTLDEIGEEEDATVQALVTVDEVIDEEELNMEEMVKNSNSLLTLDELIDQDDCIPHSGPKDVTVLSMAEEQDLQQERLVTVDEIGEVEESADITFATLNAKRDKRDSIGFISSQMPEDPSTLVTVDEIQDDSSDFHLMTLDEVTEEDENSLADFNNLKEELNFVTVDEVGDEEDGDNDSKVELARGKIEHHTDKKGNRKRRAVDPKKSKLDSFSQVGPGSETVTQKDLKTMPERHLAAKTPMKRVRLGKSSPSQKVAEPTKGEEAFQMSEGVDDAELKDSEPDEKRRKTQDSSVGKSMTSDVPGDLDFLVPKAGFFCPICSLFYSGEKAMANHCKSTRHKQNTEKFMAKQRKEKEQNETEERSSR
What is the function of this protein?
Transcription factor that binds to cytidine clusters in double-stranded DNA (By similarity).  Plays a key role in the silencing of unintegrated retroviral DNA: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed (PubMed:30487602).  Mediates transcriptional repression of unintegrated viral DNA by specifically binding to the cytidine clusters of retroviral DNA and mediating the recruitment of chromatin silencers, such as the HUSH complex, SETDB1 and the histone deacetylases HDAC1 and HDAC4 (PubMed:30487602).  Acts as an early regulator of adipogenesis by acting as a transcription cofactor of CEBPs (CEBPA, CEBPD and/or CEBPG), controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1 (PubMed:21602272).  May also regulate alternative splicing of target genes during adipogenesis (PubMed:25024404).
What are the official names of this protein?
Zinc finger protein 638, Nuclear protein 220, Zinc finger matrin-like protein.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: PNP2_ARATH
Sequence: MSSIVNRASSASLPNFLAWRALGFRTICSGRLGFAPSVPDSPVSAGTKILESFKEEFEVGSRVVSFETGKIARFANGSVVLGMDETKVLSTVTCAKTDSPRDFLPLTVDYQEKQYAQGLIPNTYMRREGAPKERELLCGRLIDRPIRPLFPTGFYHEVQIMASVLSSDGKQDPDILAANASSAALMLSDVPWGGPIGVIRIGRICGQFVVNPTMDELSSSDLNLIYACTRDKTMMIDVQSREISEKDLAAALRLAHPEAVKYLDPQIRLAEKAGKQKKEYKLSMLSDKTLEKVADLAATRIESVFTDPSYGKFERGEALDNIGKDVRKVFEEEGDQESLSILPKAVDTVRKKVVRSRMISDGFRVDGRHVDEVRPIYCESHYLPALHGSALFSRGDTQVLCTVTLGAPAEAQSLDSLVGPPKKRFMLHYSFPPYCTNEVGKRGGLNRREVGHGTLAEKALLAVLPPEEAFPYTIRINSEVMSSDGSTSMASVCGGSMALMDAGIPLRAHVAGVSVGLITDVDPSSGEIKDYRIVTDILGLEDHLGDMDFKIAGTRDGVTAIQLDIKPAGIPLDIVCESLENAREARLQILDHMERNINSPRGQDGAYSPRLATLKYSNDSLRTLIGPMGVLKRKIEVETGARLSIDNGTLTIVAKNQDVMEKAQEQVDFIIGRELVVGGVYKGTVSSIKEYGAFVEFPGGQQGLLHMSELSHEPVSKVSDVLDIGQCITTMCIETDVRGNIKLSRKALLPKPKRKPASDAGKDPVMKESSTVYIENSSVGEIVASMPSIVTPLQKSRLSVPAVVIRTAVECNEAEKSSPVNDNDKPRRAATSKPDRKPKSTASKLIATQKEEEALESIAPEETSAECGEILKQDGKLKSVSPKNNSTASNLVSFSKAKKSTMKENLSENKAEESASVSTRKLKIGTEMTATVDHVRALGLVLDLGGEIRGMYIFQGDKDKFKKGDTLRVKCTSFNTKGVPVMALVDEEGEE
What is the function of this protein?
Involved in the 3'-end maturation of mitochondrial mRNAs, rRNAs and tRNAs.  Functions as a poly(A) mRNA 3'-5' degrading phosphorylase and is required for the degradation of highly expressed transcripts of non-coding regions.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase 2, mitochondrial, AtmtPNPase, Polynucleotide phosphorylase 2, PNPase 2.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPB_POPTM
Sequence: MRINPTTSGPGVSALEKKNLGHIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVSQQINVTCEVQQLLGNNRVRAVAMSATEGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDDLRPVDTGTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEENIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGTLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPQIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFKLILSGELDSLPEQAFYLVGNIDEATAKATNLEMENNLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: DCD_SACD2
Sequence: MSIKSDKWIRRMAENEGMIDPFEPGQVRYNADEQRLISYGTSSYGYDVRCADEFKIFTNVHSAIVDPKNFSDDSFVDVKSDVCIIPPNSFALARTVEYFRIPRSVLTVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGVAQMLFFESDEVCETSYGDRGGKYQGQRGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CDCA4_MOUSE
Sequence: MFARGLKRKYGDQEEGVEGFGTVPSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMSQDGVWHGMAPQNVDRAPVERLVSTEILCRTVRGAEEEHPAPELEDAPLQNSVSELPIVGSAPGQRNPQSSLWEMDSPQENRGSFQKSLDQIFETLENKNSSSVEELFSDVDSSYYDLDTVLTGMMSGTKSSLCNGLEGFAAATPPPSSTCKSDLAELDHVVEILVET
What is the function of this protein?
May participate in the regulation of cell proliferation through the E2F/RB pathway (By similarity).  May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation.
What are the official names of this protein?
Cell division cycle-associated protein 4, Hematopoietic progenitor protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: IRAD_SALPB
Sequence: MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCAVPGGETLPPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_ECO8A
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: Y181_MYCTO
Sequence: MTATVEIRRAADRAVTTTSWLKSRHSFSFGDHYDPDNTHHGLLLVNNDDQMEPASGFDPHPHRDMEIVTWVLRGALRHQDSAGNSGVIYPGLAQRMSAGTGILHSEMNDSATEPVHFVQMWVIPDATGITASYQQQEIDDELLRAGLVTIASGIPGQDAALTLHNSSASLHGARLRPGATVSLPCAPFLHLFVAYGRLTLEGGGELADGDAVRFTDADARGLTANEPSEVLIWEMHAKLGDSAT
What is the function of this protein?
Putative quercetin 2,3-dioxygenase.
What are the official names of this protein?
Putative quercetin 2,3-dioxygenase MT0190, Putative quercetinase, Pirin-like protein MT0190.
What is the protein family that this protein belongs to?
Belongs to the pirin family.
Protein: ATPI_OCHNE
Sequence: MFFSLAAVEVGTHLYWEIGGLEVHGQVLLITWLVLAIILTLAILGTLKLEQVPKGVQNFLESVFEYVSGIAKDQIGEYHYRPWVPFVGTLFLFIFVANWLGALIPWKLIHLPEGELAAPTNDINTTVALSLLTSISYFYAGFKEKGLGFFARYISPTPIFLPINILEDFTKPLSLSFRLFGNILADEIVVSVLCLLVPLLIPLPVMVLGIFASSVQALVFSTLSAAYIGESIE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: OBG_ALKMQ
Sequence: MFIDKAKIHLKSGKGGDGAVAFRKEKYVPAGGPAGGDGGKGGNIIFVVDEGMRTLMDFRYKMHYSAENGENGKGRMQYGKDGEDLILRVPPGTIIREEKTGHLVADLTQPKERRIIAKGGKGGKGNVHFKSATRQAPQFAIAGVKGEELTVTLELKLIADVGLVGFPNVGKSTLLSVVTSAKPKIADYHFTTLTPNLGVVRTKRGDSFVLADIPGLIEGAHEGTGLGHEFLRHVERTKLLIHVLDVAGIEGRDPLEDFEKINEELKLYNEKLSTRPQVVAANKTDVMGENENLKKLTEALAEKGIEVFPVSAATKQGLDELLDYVSIKLKELEDTEVELEEVEEEKLYELKEKDTNQFTVKKEDDTYIVEGDFLERLIMSTNFEDMDSLTYFQKVLRRKGIIDELKKLGIEDGEFVKIYDVEFEYFH
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_PHOV8
Sequence: MKFIGIIPARYASTRFPAKPLAVLGGKPVIQRVYEQVSGILDEAYVATDDERIESAVKAFGGKVVMTSVHHKSGTDRCYEAYTKVGRGYDVVVNIQGDEPFIQKSQLEAVKACFEDPATQIATLVKPFIPDDGLEALENVNSPKVVVGKNMNALYFSRSIIPFQRNVEKEGWLKGHTYYKHIGLYAYRADVLKEITSLPQSSLELAESLEQLRWLENGYTIKVGISEVETIGIDTPQDLARAEAFLKQREGE
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCRK_BACSU
Sequence: MLGGIEAGGTKFVCAVGREDGTIIDRIEFPTKMPDETIEKVIQYFSQFSLQAIGIGSFGPVDNDKTSQTYGTITATPKAGWRHYPFLQTVKNEMKIPVGFSTDVNAAALGEFLFGEAKGLDSCLYITIGTGIGAGAIVEGRLLQGLSHPEMGHIYIRRHPDDVYQGKCPYHGDCFEGLASGPAIEARWGKKAADLSDIAQVWELEGYYIAQALAQYILILAPKKIILGGGVMQQKQVFSYIYQYVPKIMNSYLDFSELSDDISDYIVPPRLGSNAGIIGTLVLAHQALQAEAASGEVRS
What is the function of this protein?
Seems to be involved in the degradation of glucomannan.
What are the official names of this protein?
Putative fructokinase, Glucomannan utilization protein E.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: HPR_METMA
Sequence: MRQESLVTKYDYDFENDSIFFYGSNKKYRSSIDLDGIILDIGEDDQIMAIEILDASNRFNLAKEDLRNIKYFEARIEVSEENIRLTMKMSVNKRNKLVDKGLDALGLNSINLPISTQGIELNC
What is the function of this protein?
May play a role in purine salvage.
What are the official names of this protein?
Putative hypoxanthine phosphoribosyltransferase.
Protein: YDHC_BACSU
Sequence: MDDFKLDKPTPYYLQFYNQLKKMIFNGTFKPGERINETQLAKSFGVSRSPIREAMRLLEKDGLLKADDRNGFSITSLTAKDVDEIYKIRIPLEQLAVELVIDEADEEELTILEKQLEETEKAIHNGTEDTEIIRLNQKFHELLVDFSHNRHLKNLLEHVNDLIHFCRILNYTGDHRAETILREHRRIFEEVKKKNKEAAKQHVLAHFNHDCEHLKHVLEEGKEN
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YdhC.
Protein: RL21_NOSP7
Sequence: MTYAIIETGGKQIRVEPGRFYDIELLPTEPDEKVTIDSVLLVQHDGAVSIGQPLVTGATVEGTVMRHYRGRKVLVYKMKPKKKTRKKRGHRQEITRLMIDSITLNGEVFVAQGEAEKETPVLDETPAEEVETAAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: HIS6_YERPS
Sequence: MLAKRIIPCLDVKDGQVVKGVQFRNHEIIGDIVPLAQRYAQEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIKSVEDASQILTFGADKISINSPALADPTLITRLADRYGVQCIVVGIDTWYDTESDSYQVYQFTGDEKRTKATTWQTEDWVKEVQLRGAGEIVLNMMNQDGVRNGYDLRQLQQMRAICHVPLIASGGAGTPEHFLEAFRDADVDGALAASVFHKQIINIGELKKYLSEQGVEIRVC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y327_RICBR
Sequence: MQKLLSLIIVALVLYNIAKLKISSDDNNATIIEQASVNNSANNENQVSINNDPPVSLNGNLFERTISKIVINALKTEEGKAFFENILQPLNKPIDTKDYTIPVHKDLITSLFKINTIGTGNVGPASCGHVVTVFYQISDMSNNLISEDTKTFTIGSGAVMLGLDNVIVGMNVGQAREAIIPAKYAASVGANNDNADSAYRVNVMLKSILPQNFINSNEVKIYDNEIAYRIPLLCGEKIAFNAKITRLANGEVLYDSKAKGQKVDMKIGDITYPLIFSYALQGKVPVGTRTVIAKGQTFKALGSNINKIISQESLPLNEYLMLEINDFK
What are the official names of this protein?
Putative peptidyl-prolyl cis-trans isomerase RBE_0327, PPIase RBE_0327, Rotamase RBE_0327.
Protein: RHAG_MOUSE
Sequence: MRFKFPLMAISLEVAMIVLFGLFVEYETPQNASQKNASHQNASQQGNTSSSAKKDQFFQLYPLFQDVHVMIFVGFGFLMTFLKKYGFSGVGFNLFLAALGLQWGTIMQGLLHSHGKEFHFGIYNMINADFSTATVLISFGAVLGKTSPIQMLIMTILEIAVFAGNEYLVTELFEASDTGASMTIHAFGAYFGLAVAGVLYRPGLRCEHPNDESVYHSDLFAMIGTLFLWIFWPSFNSAIADPGDHQYRAIVNTYMSLAACVITAYALSSLVERRGRLDMVHIQNATLAGGVAVGTCADMEIPLYAAMTIGSIAGIISVLGYKFFSPLLANKLMIHDTCGVHNLHGLPGVFGGLASIVAISWGMSTASMAMQAAALGSSIGSAIVGGLLTGLILKLPIWNQPPDEYCYDDSVSWKVPKFRELDNRFFQHANHNHVEHEV
What is the function of this protein?
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.  Involved in ammonia transport across the erythrocyte membrane.  Seems to act in monovalent cation transport.
What are the official names of this protein?
Ammonium transporter Rh type A, Erythrocyte membrane glycoprotein Rh50, Rhesus blood group family type A glycoprotein, Rh family type A glycoprotein, Rh type A glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: MOAA_CLOB6
Sequence: MLDKHGREINYLRVSVTDRCNLRCVYCMPPEGIIKKEHDNIMRYEEIFKVVKSASLLGVNKIRFTGGEPLILKNIDKLIYNTSKISSIKDIAMTTNAILLEDMVEELKKAGLKRVNISLDSLKEDRFKSITRGGDINKVFKSIEKSLSIGMRPIKINTVIMKGINDDEIDDFMNLTKEYPISVRFIELMPIGEGRRLYKDGYISSEEIISKHSDLIPVETEKSSTALLYKFKESKENIGFISPMSCKFCSGCNRVRLTSEGTLKPCLHSEKEVNLKNYVGNNQALLSKINETIYNKPLEHHMIEEKESKSKKMMYQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: GLMM_SACD2
Sequence: MARKYFGTDGIRGLVGEGVITPQFFLQLGWAVGKVLAQQNGDKSGGLVLIGKDTRISGYMFESALEAGLISAGVDVGLLGPMPTPAIAYLTRTFQASAGIVISASHNPYTDNGIKLFNTDGTKLPDDVELAIEDQLDRAMTTASKLGKARRIADAEGRYIEFCKGSLPWGFNLRGLNIVVDCANGATYEVAPKVFGELGANVIPIANKPDGLNINLDCGSTKLNQLQKHVLETGADMGIAFDGDGDRVMFVDEKGEVLDGDQLLFIIASHKHKNGGCSGVVGTLMSNFGFELGLKNQGIPFERAKVGDRYVIEAMKNNGWQVGGESSGHIVCSDVTTTGDGIIAALQVLLALKAEKQSLHQLKLRMQKMPQVMINVRVTNKVDLDSHEQVQAAIASAEKRLDGKGRVLLRASGTEPVIRVMVEGQEHQLVASLAQELADIVGEAVA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ATP6_ACTPJ
Sequence: MAGTTAEYISHHLSFLASGDGFWAVHLDTLFFSLLAGVIFLFVFSRVAKNATSGVPGKLQCFVEIVIGWVDGLVKDNFHGPRNVIAPLALTIFCWVFIMNAIDLVPVDFLPQLANMFGIHYLRAVPTADISATLGMSICVFFLILFYTVKSKGFGGLVKEYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYMADNFALQALGIPLHLVWAIFHILVITLQAFIFMMLTIVYLSIAYNKADH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEXA_OENOB
Sequence: MAETKQLGILRFIYEKQNEKGYPPTVREIGEAVGLSSTSTVHGHIDRLEKHGLLHKDPTKPRAIEITEKGLRALGVPETPGKVPIIGLVTAGMPILAVEQAATEFLPIPSDLERFDGDLFVLRVSGTSMINIGILDGDMVFVRKQDYADNGDIVVAMTTDFGNGEGEATVKRFFKESNHYRLQPENDTMAPIIVKNVSILGKVVGLYRNSIY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL37A_SCHMA
Sequence: DKRTKKVGIVGKYGVRYGASLRKTIKKIEISQHAKYNCNFCGKDSLKRKAAGIWECKACKKVVAGGAYVCSTTAATTIRAAIRRLRDAHES
What are the official names of this protein?
60S ribosomal protein L37a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: PSM_MYTCA
Sequence: KGYQYLPVVLKVIAMTTIKNVSEHQAGICVTMSVKLPAILTRQLAQTSCPSLPDPMNRYGYLAPQYGGLRIRACPSGTIYSENQCRYKSNMNGNGGLRGSARKQFRQCSAEFKINFDDGFKDISKGGLAFDYSHISLRRGKGVFVGNSKLYIWGFQSRFLGKTFAIRMKVKIKRGAGKYRPEPIISNCGPNGDSSVEIVVHRGKVIFKAKTSDNPEAVFITEDYDDDKWTDLTYYYDGNHFGGSCNGRPFRQRTGGNLEIRDNPMTIGLCTGQNGFHGEIDELEIYTACIPKDM
What are the official names of this protein?
Shell matrix protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMC_MARN8
Sequence: MSALPNTHEVLLRNAHLLNGRPALLGVSDASLLPRCPVPGIAMTEHAGLWQILSHDTDWAGCFGYEPDRQQQGSCDTVVVFLPKARAECELRLALARYLGKPGAALVVIGEKKEGIAGAIKQFSVVAGEVVKVDSARHCQVWCGRNTQPLTEFRLTDWLSWTELSCAGVALSVAGLPGVFSLGRLDDGTRMLLETLAESPLGVDRVFDFACGAGVIGSWLHGFHQLAGKMPIRVDGTDVQAQAVFCARESYRKAGVNGEIFAADGLAVVQGNWPAVISNPPFHTGVKTDTSMTEQFLAQVAAHLAHGGELRLVANSFLPYEALIRQHIGPVEKLAQDRRFTVYRAFRKKSG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.