PharMolix/UniProtQA huggingface dataset:
Protein: NU6C_AMBTC
Sequence: MDLLGPIHDILLVSLGSGIILGSLGVVLLTNPIYSAFSSGLVLVRISLFHILSNSYFVAAAQLLIYVGAINVLIIFAVMFMNGSEYYNNFHLWTVGDGISSVVCTSILFSLIATILDTSWYGIIWTTRSNQIIEQDLTSNVQQIGIHLSTDFFLPFELISIILLVALVGAIAMARAE
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HTF_EUBPO
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, EubPo-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: YFCL_ECOLI
Sequence: MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELESGDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWENLFQQASQQ
What are the official names of this protein?
Uncharacterized protein YfcL.
Protein: TRMB_CAUSK
Sequence: MTHPQQPHGPLRSFGRLKSRPVKPRQQALLDTLLPQIAVPTAPFQPRDLMPEAQEVWLEIGFGGGEHMAAQAGKRPDVLMIGAEPFVNGVASAVRHVEEQALKNVRIHEGDARDVVGWLPDASIDRLFIMFPDPWHKARHNKRRLVQPAFVAELARVLKPGAGFRFATDWADYAQWTVERVLADPAFRFADAEAVRNAPPADHVTTRYEEKKLGDCAPVFLDFVRI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL36_VIBVY
Sequence: MKVLKSLKSAKARHPDCQIVRRRGRLYVICKSNPRFKAVQK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TF3C6_MOUSE
Sequence: MASPNAMAAAVDPIWEDLEEEEEELEEEQFVLVELSGIIDSDFLSKCENKCKILGIDTERPIMQVDSYVFAGEYEDTLGTCVIFEEGVERVDPEGTDKTVLKYKCHTMKKLSMTRTLLTEKKEGEENIDGVEWLQMKDNDFSYRPNMICSFLHEHEDEAAGPASDKPVELEDQESQMKGSAEQTQEQEKVEHSEVEDPAPSGETPSEMESSVFMGTQDGNVSQNNQS
What is the function of this protein?
Involved in RNA polymerase III-mediated transcription.  Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters (By similarity).
What are the official names of this protein?
General transcription factor 3C polypeptide 6, Transcription factor IIIC 35 kDa subunit, TFIIIC 35 kDa subunit, TFIIIC35, Transcription factor IIIC subunit 6.
What is the protein family that this protein belongs to?
Belongs to the TFIIIC subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR9_METFK
Sequence: MAVIKRALISVSDKTGILEFAKALAEFGVEILSTGGTAKLFRDNGIPVTEVSDYTGFPEMLDGRVKTLHPKIHGGLLGRRDLPEHVTAMQAAGIPDIDMIVVNLYPFEATVARPDATLEDAIENIDIGGPAMVRSAAKNWQDVAVLTDASQYEEVLAEMRSTGGATSKATRFALSVAAFNRISNYDGAISDYLSSFNADGTRNEFPGQINGRLVKVQDLRYGENPHQQAAFYRDLYPAPGSLVTAQQLQGKELSYNNIADADAAWECVKSFDSTACVIVKHANPCGVALGATPLEAYQKAFQTDPTSAFGGIIAFNHTLDGAAAEAVSKQFVEVLIAPDYTEEALAVFKAKANVRVLKIALPVGGDSPWSRGRNSHDTKRVGSGVLIQTADNHEISAADIKVVTKKQPTPEQLEDLLFAWRVAKYVKSNAIVFCGNGMTLGVGAGQMSRVDSTRIAAIKAQNAGLSLQGSAVASDAFFPFRDGVDVLAEAGASCVIQPGGSIRDDEVIAAADEHGLVMIFTNIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: JANB_DROMA
Sequence: MKMFKSLSLIPRIVSPFQKCYSTDLISLVGVPRVKITKGQNRYLLVNIHTHGFTKYGRVIVRGADVDNHLAIFDSILEELEPEGICAKILGGGRILNEPDNKKIKIYGTSRTFGGADHTRTRNILQAWTTYKDFKITVKQ
What is the function of this protein?
JanA and janB regulate somatic sex differentiation.
What are the official names of this protein?
Sex-regulated protein janus-B.
What is the protein family that this protein belongs to?
Belongs to the janus family.
Protein: RXLAA_PHYIT
Sequence: MRRYAALMVIDAVLLSTSQALSSSHASELRSQLSAADAMFPSAERDGGIPNKRSLRRISVTESNDGERDEERGFQISILTKLQKWATKMKLPKTTKNLQFRIWPKEKKDPKAVYAELKLAGLDPKAAKANPEFADYLAYSKIWNHRGGRYMTRS
What is the function of this protein?
Secreted effector that is involved in host plant infection (PubMed:31234322).  Increases the susceptibility to P. infestans and reduces the plant growth (PubMed:31234322).  Affects the expression of host genes (PubMed:31234322).  PITG_15718-induced genes such as abscisic acid 8'-hydroxylase, a homolog of a salicylic acid-binding protein or a cysteine protease inhibitor gene, may negatively regulate the plant immunity or vegetative growth (PubMed:31234322).  The down-regulated genes include cytochrome P450 monooxygenases essential for lignification and defense against predators and pathogens, and a member of YUCCA gene family, which is an important regulator of the phytohormone indole-3-acetic acid (IAA) biosynthesis (PubMed:31234322).  Reduction of the content of IAA particularly results in the suppression of the plant immunity and reduced growth (PubMed:31234322).
What are the official names of this protein?
Secreted RxLR effector protein PITG_15718.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: UBIG_ECO45
Sequence: MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-octaprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone-8 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: TNFB_BOVIN
Sequence: MTPPGRLYLLRVCSTPPLLLLGLLLALPLEAQGLRGIGLTPSAAQPAHQQLPTPFTRGTLKPAAHLVGDPSTQDSLRWRANTDRAFLRHGFSLSNNSLLVPTSGLYFVYSQVVFSGRGCFPRATPTPLYLAHEVQLFSPQYPFHVPLLSAQKSVCPGPQGPWVRSVYQGAVFLLTRGDQLSTHTDGISHLLLSPSSVFFGAFAL
What is the function of this protein?
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity).  In its heterotrimeric form with LTB binds to TNFRSF3/LTBR.  Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
What are the official names of this protein?
Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane- associated.
Protein: Y1029_BIFLO
Sequence: MSFNDPFSILFGNGGDSRRNNANNDDPIILDVEADGDGPARNTNAGPSGSSRPPRGPANPRITRKPASGGSGGSRGSKILIGVVLALAIIVGLFFGLSRFITDLMWYGQLGFQSVVWTQLGVKIGLWVAYALLMALTGFVSAWLAIRARPDSADGSTIRINGDVVEVGKSVSSKTARRVAVVISLIVGVIFGSQFNANWSEILLMFNAQSFGTTDPQFGLDNGFYVFVLPGLKLVLAAVAMLLGVGLVFSVVTHVLMGGIRITMPVNGRGLFSITKRCRRQLGIWLMLNMFAWAVRQMIGVFDQLTVQGSRITGASYTAVHANIPVTFIMAALTAILGVVLGIWLMRSHTLEGQASIGVRASAALKAWRVPVTSIAVVVVVGLVLTVAWPVLLQRFRVNPNAQEMESTYIQRNIDATRAAYGLDKLKTEQYKVTDKGEQGALAKEGDTTAQIRLLDPQVVSPTFKQLQQSKQYYTFADTLAVDKYEIDGVSQDTVIAARELDLAGNDNRNWVNDHTVYTHGYGVVAAYGNKVTADGQPEFFESGIPTQGKLTESEKYEPRIYFSPNTTEYSIVGAPEGTQAWEFDYPTGSEGALTTFKGDGGPSVGNLFSRILYAIRFGSDQILFSDRVTSESQILYDRSPKERVAKVAPYLTLDGRVYPAVVDGRVKWIVDGYTTSDAYPYSQMTDLGSATKDSTTVSSATVSSLGSQKANYIRNSVKATVDAYDGSVDLYVWDQSDPVIKAWEKIFPGQYHQLSDISGDLMSHMRYPESLFKVQRELLSKYHVTSANQYYSGEDFWQTPVDPTESQSQQDQDILQPPYYLTLQTGGTKEPVFSLSSTYIPAGQSTREILTGFLSVDSDAGNEKGKIGSNYGTIRLQELPKDSNVPGPGQAQNNFNANADVSKELNLLQSGDTQVVRGNLLTLPLGGGLVYVQPVYVKSSGATSFPLLKKTLVAFGDQVGFADTLDEALDQVFGGDSGAAAGDAENVSGDQSGSDTNGGQSGTTDGKSDSGSSSDRSPELQQALNDAAQAMKDSQSAMKNGDWTAYGKAQQELEDALNKAIELDK
What are the official names of this protein?
UPF0182 protein BL1029.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TBL29_ARATH
Sequence: MQPWRRKFPLFETGVTMKQRKNSNLSIFVVVFSVFLFGIFMYNEDVKSIAEFPFSTSKPHDVHDEATPITEITTLPVQESIKNSDPIQESIKNADSVQDSVKDVAEPVQEEVSKTEEVKKIELFAATEDEEDVELPPEECDLFTGEWVFDNETHPLYKEDQCEFLTAQVTCMRNGRRDSLYQNWRWQPRDCSLPKFKAKLLLEKLRNKRMMFVGDSLNRNQWESMVCLVQSVVPPGRKSLNKTGSLSVFRVEDYNATVEFYWAPFLVESNSDDPNMHSILNRIIMPESIEKHGVNWKGVDFLVFNTYIWWMNTFAMKVLRGSFDKGDTEYEEIERPVAYRRVMRTWGDWVERNIDPLRTTVFFASMSPLHIKSLDWENPDGIKCALETTPILNMSMPFSVGTDYRLFSVAENVTHSLNVPVYFLNITKLSEYRKDAHTSVHTIRQGKMLTPEQQADPNTYADCIHWCLPGLPDTWNEFLYTRIISRS
What is the function of this protein?
Xylan acetyltransferase required for 2-O- and 3-O-monoacetylation of xylosyl residues in xylan (PubMed:23659919, PubMed:30083810, PubMed:32354790).  Catalyzes the 2-O-acetylation of xylan, followed by nonenzymatic acetyl migration to the O-3 position, resulting in products that are monoacetylated at both O-2 and O-3 positions (PubMed:32354790).  Is necessary for the formation of the functional xylem, which is required for water transport to aerial tissues (PubMed:21408051, PubMed:23340742).  Acts as negative regulator of cold acclimation (PubMed:17316173).  Involved in water economy as well as salt tolerance (PubMed:19061521, PubMed:19054354).  Regulated at the transcriptional level by NAC012/SND1 (Probable).
What are the official names of this protein?
Xylan O-acetyltransferase 1, Protein ESKIMO 1, Protein trichome birefringence-like 29.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: FAR10_DELRA
Sequence: SAQGQDFMRF
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
FMRFamide-like neuropeptide SAQGQDFMRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ADDB_STAAS
Sequence: MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDVLQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVFLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYIAMTRARQDVTFSYRLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: SDHD_SALHS
Sequence: MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPYLAKAFPQTAAAGGMIESDVVAIPAMQKRLEKEYGQTIDGEMLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAAAAYQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: GP2D_CHLTH
Sequence: MVNYSNCHFIKSPIHLENQKFGRRPGQSIKISPKLAQNGMVEVIGLDFLSSHYHALAAIQRLLTATNYKGNTKGVVLSRESNSFQFEGWIPRIRFTKTEFLEAYGVKRYKTSRNKYEFSGKEAETALEALYHLGHQPFLIVATRTRWTNGTQIVDRYQTLSPIIRIYEGWEGLTDEENIDIDLTPFNSPSTRKHKGFVVEPCPILVDQIESYFVIKPANVYQEIKMRFPNASKYAYTFIDWVITAAAKKRRKLTKDNSWPENLFLNVNVKSLAYILRMNRYICTRNWKKIELAIDKCIEIAIQLGWLSRRKRIEFLDSSKLSKKEILYLNKERFEEITKKSKEQMEQLEQESIN
What are the official names of this protein?
Virulence plasmid protein pGP2-D, Protein P-4.
Protein: RL1_SYNWW
Sequence: MKRGKNYQQAGEKFDRLTLYEPKEALELVKEIAKAKFDETVEVHIKLGVDPRHADQQVRGTVSLPNGTGKTRKVLVFAKGEKIKEAELAGADYVGGEDLAEKIQGGWFDFDVAVATPDMMAVVGKMGKILGPRGLMPNPKAGTVTFDIERTIKELKAGRIEYRVDKSAIVHAPIGRISFEVDKLQENLNAFAEALLKARPAAAKGQYMRSVTVCSTMSPGVKINPLVLMAANK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PHNW_CUPNH
Sequence: MIRGNDPILLTPGPLTTSLATKQAMLRDWGSWDAAFNAITRSLCDDLVRIVHGEGTHVCVPMQGSGTFSVEAAIANVVPRDGKVLVPQNGAYCQRILKICKVLGRASVELPIPEDQPATAALIEEAIRRDPSITHVAQVHCETGAGVLNPLQEIAALCQRLGKGLIVDAMSSFGAIEIDARTMPFDALVAATGKCIEGVPGMGFVLVKKDVLEASQGNSHSLALDLYDQYVYMQKTTQWRFTPPTHVVAAFRTALDQFLEEGGQPVRGARYRRNCDALVQGMAALGFRAFLPAAVQAPIIVTFHAPADARYDFKTFYARVRERGYILYPGKLTQMETFRVGCIGAIDDNEMRNVVTAIGEVLREMGIKMQAPLAEAA
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: RS28_HALSA
Sequence: MSAEESEEGATPAEVIEVVGKTGMHGEAMQVKCRIQEGGNQGRIITRNVLGPVRVGDVIQLKETAREADSIGGQ
What are the official names of this protein?
30S ribosomal protein S28e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: TPX_STAAR
Sequence: MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSEASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: M2GD_RAT
Sequence: MLRLGALRLRGLALRSSQGRPSSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS
What is the function of this protein?
Catalyzes the demethylation of N,N-dimethylglycine to sarcosine.  Also has activity with sarcosine in vitro.
What are the official names of this protein?
Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YCIB_SHEPC
Sequence: MKQLLDFLPLVIFFAVYKFFDIYIASGALIAATALQLIVTYALYKKLEKMHLITFAMVTVFGTLTLVFHDDAFIKWKVTIIYALFALALGISQLLNKSILKSMLGKEMQVADKIWAHITWYWVIFFATCGLVNIYVAFSLPLETWVNFKVFGLTALTLVNTVITVFYLYKHLPEDQRKELK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLD_MAGSA
Sequence: MNNHGLKLDNIRRAFKQGKDDLEVLKGANLEIRAGEIVALVGPSGAGKSTLLHIAGLLERPDGGEVFLAGNPAGALGEKERTQLRRLHLGFVYQYHHLLPEFSAIENVVLPQMIAGVPQAKARERAMELLGRMKLAERAEHRPGQLSGGEQQRVAICRALANAPRVLLADEPTGNLDPHTADGVFDELIRLVKGSGVAALIATHNPDLAARMDRVVKMSEGLLVEV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HEMH_SALCH
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDGAYIDALAKSARESFARHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEBA_PROMS
Sequence: MFDSLVDFLKTNIDQLNGHEVQISSEFKEHHNEDSKYIIKNWLFSSPEYRKWRITRLDGGKKLQVFNTVAYPNFESELPILGADILWFGTSQKLLAILDYQPLIQESKYLEKYCSSLGIIKEEYSAFDNNKMKNIYDSKKYFSPWVIICRGNKLNLDRDLNDIFHSFVNNYLNIYKSNPVNQFLNSEEIKINQIKYDKYSFEKDPADKLFKSFFGEKWTKKFINKFLFTLNNEIIH
What is the function of this protein?
Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge.
What are the official names of this protein?
15,16-dihydrobiliverdin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: RL44E_HALSA
Sequence: MEMPRRFNSYCPNCDEHHQLEAEKVRSGRSSGMKWDARRTKRANASIGNHGRFSKVPVGNKPTNRTDLKYRCSECGNAHLREGWRAGRLVLQE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L44e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
Protein: SODE_RABIT
Sequence: MLALVCSCLLLAALPADTWSGPAAVELGSDTVEQIRDTHAKVTEIWQALTQQRAAQGEPAGALHAVCRVQPSATLDAAQPRVSGLVVFRQLGPGAQLEAFFDLEGFPVEANLSSRAIHVHQFGDLSQGCDSTGAHYNPLAVQHPQHPGDFGNFAVRDGRLWKYRSGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNAASVENGNAGPRLACCVVGASGPAPWARQAQEHAERKKRRRESECKAA
What is the function of this protein?
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
What are the official names of this protein?
Extracellular superoxide dismutase [Cu-Zn], EC-SOD.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Golgi apparatus, trans-Golgi network.
Protein: RAB13_BOVIN
Sequence: MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFRIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRLKNNNKPPSTDLKTCDKKNTNKCSLA
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab is involved in endocytic recycling and regulates the transport to the plasma membrane of transmembrane proteins like the tight junction protein OCLN/occludin.  Thereby, it regulates the assembly and the activity of tight junctions.  Moreover, it may also regulate tight junction assembly by activating the PKA signaling pathway and by reorganizing the actin cytoskeleton through the activation of the downstream effectors PRKACA and MICALL2 respectively.  Through its role in tight junction assembly, may play a role in the establishment of Sertoli cell barrier.  Plays also a role in angiogenesis through regulation of endothelial cells chemotaxis.  Also involved in neurite outgrowth.  Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome.  Finally, it has been involved in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore may play a role in glucose homeostasis (By similarity).
What are the official names of this protein?
Ras-related protein Rab-13.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Cell junction, tight junction. Golgi apparatus, trans-Golgi network membrane. Recycling endosome membrane. Cell projection, lamellipodium. Note=Tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions (By similarity). Relocalizes to the leading edge of lamellipodia in migrating endothelial cells (By similarity).