PharMolix/UniProtQA huggingface dataset:
Protein: TDA6_YEAST
Sequence: MHCVLARILLWFLIVDLSVIRALVLPPLKDYDPLEPLMKRDMAMGQRNRFKVDGQLPPILNSTDVTDDQRSLHTPGEIPSYVINHCPLVHLYSEEKYWPSDIAEYVQNFQIKDKNGNSISTHENLTLHDLKAEYHVDLFGNKTETHIPSSEVFLTSLDDFDKDPKWLLGHLPEYGTGYNSKAPAILIVVDKGNGWVDAFWFFFYPFNHGPFIMGHGPWGNHVGDWEHSLVRFYKGIPKYLWMSAHSSGTGYRYEAVEKFKKLRKRKQQDSDDGGDTILERPLIFSARGTHANYASAGQHAHDIPFFFMPLSDFTDRGPLWDPSLNFYSYTFDGKTVTPSSEREESLGLDWLHFQGGWGDQQLPARDPRQKWCVAQWKYIGGPRGPLFKKLDRLNLCGGVKKWNFWNGGCPARRLIKKAEGLDSESTDLMGDNCGVLLYRIRPKWLRGILRFLMWRGILCSLMEFFTN
What is the function of this protein?
Involved in vacuolar protein sorting.
What are the official names of this protein?
Putative vacuolar protein sorting-associated protein TDA6, Topoisomerase I damage affected protein 6.
What is the protein family that this protein belongs to?
Belongs to the VPS62 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL25_CALBD
Sequence: MEPVLVYNRRDIFTKSNLNKLRKEGYIPAVAYGDDIKSLPGYVSKKEFEKLYHQKGLAGKIKISIDGKERTALIKEVQTHYTKGNIIHVDFQILSENKPIYVEVPIIFENAEILKSRGLVLQRQMDTVEIEGLPKDIPEHLVIDLMAYEKPTAIKLKDIKLPEGIKITEDLDEVVAVIDVSEITEEPEVEEKKEETSSNA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: DUT_SALPK
Sequence: MKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RS3_SHIDS
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ECPB_KLEP7
Sequence: MKKHLLALGLLLAGVSPAQALDVGDISSFMNSGSSTLSKTIKNSTDSGRLINIHLERLSSPLDGGQVIPMDKPDEVLLTPASLLLPAQASDVIRFFYKGPADDKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQVNYRFQYANGSLTNTGNATLRILAYGPCLKAADGKECKENYYLMPGKSRRFTRVDTADKKGRVALWQGEQFVPVK
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP plays a dual role in early-stage biofilm development and host cell recognition (By similarity).
What are the official names of this protein?
Probable fimbrial chaperone EcpB.
What is the protein family that this protein belongs to?
Belongs to the EcpB/EcpE family.
Protein: TX11A_MYRGU
Sequence: MKLLYLLLTLAIIFVLTIVHAPNVEAKALADPESDAVGFADAFGDADAEATGGLGRLIGKIAKKGAKIAAEAAANAAAEKAAEALG
What is the function of this protein?
Toxin that may interact with target cell membranes, producing a concentration-dependent leak in ion conductance, possibly via multimeric pore formation (Probable).  It produces an immediate sharp increase of calcium concentration in all DRG neurons (PubMed:30214940).  This influx in calcium stabilizes without resulting in any observable dye leakage, showing that the effect is not simply cytolytic (PubMed:30214940).  This toxin may be one of the major contributors to the pain associated with envenomation (PubMed:30214940).  The toxin also displays a weak cytotoxicity (on HEK cells) and some antimicrobial activity (MIC=2. 5 uM on C. neoformans (var.  grubii), MIC=10. 2 uM on S. aureus), but is not hemolytic to human erythtrocytes (PubMed:30214940).  In vivo, intraplantar injection into mice causes spontaneous nocifensive behavior (licking, flinching, or shaking of the paw), which lasts 5-7 minutes (10 and 100 uM tested).  Mechanical and heat hypoalgesia are observed at 20 and 25 minutes after injection (highest dose tested of 100 uM) (PubMed:30214940).  In vivo, injection into crickets (A. domesticus) causes an immediate, dose-dependent, reversible and nonlethal incapacitation that lasts about 53 minutes at the highest dose tested (60 ug/g) (PubMed:30214940).
What are the official names of this protein?
U-myrmeciitoxin(01)-Mg1a, MIITX(01)-Mg1a, U-MIITX(01)-Mg1a.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: MURC_BRUA1
Sequence: MKMPLNIGLVHFIGIGGIGMSGIAEVLHNLGYKVQGSDQSDSANVQRLREKGIEVFVGHKAENLGDAEVIVVSTAIKKNNPELVAAREKLLPVVRRAEMLAELMRFRRAVAIGGTHGKTTTTSLVAALLDAGHLDPTVINGGIINAYGTNARMGDGDWMVVEADESDGTFLKLPADIAVVTNIDPEHLDHYGNFDAVRAAFRQFVENVPFYGFGVMCLDHPEVQALVSRIEDRRIITYGSNPQAEVRFVNQRMDGAASLFDVVIRSRKGEATEIKDLRLPMPGLHNVSNATAAIAVAHELGISSDDIRRGLGSFGGVKRRFTHTGSWNGVEIFDDYGHHPVEIRAVLKAAREATSQAGGRVVAIVQPHRYTRLASLFDEFAACFNDADTVIVAPVYTAGEEPIEGVNSEELVSRIKTAGHRDARYATGPEALAPLVASIAQAGDFVVCLGAGNVTQWAYALPKELAEQGKK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_METPP
Sequence: MSASWVRGDRTAAWADLSAHFAASAANFDLRTAFAGDARRFERFGVEAPHLFADLSKNWLDAPALALLLRLAREVGLEGRRDAMLAGAPLNNTEGRAVLHTALRAPRDAAPHGSEVHATLDAMLAFAERVRDTAHSGITDVVNIGIGGSDLGPQMAVPALQAYTQAGLRSHFVSNLDGHELAPLLTQLDPQSTLFIIASKTFTTQETMANAETAKAWFLARGGRDIARHFVATTTNVDAAVAFGIDTAFGFWDWVGGRYSLWSAIGLPVAIALGATHFRALLGGAHAMDRHFATAPLERNLPVLLGLLDVWYRNFHGLTSRSVAPYHQGLRRLPAYLQQLEMESNGKCVDRDGEPLPFATSPVVWGEPGTNAQHAYFQMLHQGSDVIPVEFIAVRDTSHAHLDLPPALQPLLAEQQRKLLANCLAQSQALMAGKSEAQALAERAPTAAADMPRDVLARHRSFPGNRPSTTLLLERLDPATLGALIAMYEHRVFTSGAVWGINSFDQWGVELGKAMCSELLPRLTTGDASGLDGSTVGLLRKLGTP
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABG5_BRANA
Sequence: TTVAATKLTSLKATAGKLGYREICQVRQWAPLKSAMPHFGMLRCATSTVVKAQAQAQATATEQTTEEAVPKVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQIEEYGGEAITFGGDVSKEADVDSMMKTAVDKWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPLGRYGQPEYVAGLVEFLALSPASSYITGHTFSIHGGFAI
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase 5, chloroplastic, 3-ketoacyl-acyl carrier protein reductase 5.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid. Note=And non-photosynthetic plastids.
Protein: RLME_XYLFA
Sequence: MSHSKSSQRWLKEHFSDPFVKKAQAEGMRSRAAYKLEEILKRDRILRPNMVVIDLGAAPGGWSQQIRKQMGDRGRVIALDIVKMAPLVGIEFLQGDFRDKAVLSQLEIMLKGQPVDLVLSDMAPNKSGMDAMDQPRMMYLAELAMDFADIHVKPGGSFLIKLFHGVGSDDYIRQLRHRYKKVAIRKPLASRKRSPEVYILGDGKLTQNEVSCS
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET1_YEAS1
Sequence: MHWAAAVAIFFIVVTKFLQYTNKYHEKWISKFAPGNELSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSENKAFQAHLHKLRLLALTVPFFVFKIMYGKTPVYKLSSSTSTLFPTFVSGVWSQGWLYVLLHPLRTISQKWHIMEGKFGASKFDDMALQSVSLGIWVWALMNVINGVEFIVKQLFLTPKMEAPASVETQEEKALDAVDDAIILD
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: 3SOB8_DENAN
Sequence: MKTLLLTLLVVTIVCLDLASTMICYSHKTPQPSATITCEEKTCYKKSVRKLPAIVAGRGCGCPSKEMLVAIHCCRSDKCNE
What is the function of this protein?
Is cytotoxic against A549 cells (LC(50)=106 ug/ml).
What are the official names of this protein?
Toxin F-VIII, Toxin DaF8, Toxin TA2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XI sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MCPD_KLEAK
Sequence: MFNRIRISTSLFLLLISFCIMQLISTGLSYVALRADNHNLERITVSSQQRDALSLSWVSLLQARNTLNRAGTRAALKVPQEQVDALMGGARSSLQKADLYFNQFLDTPRADEQEQQLADATRDSYENLRGALRELIVFLENRNLQAFMDQPTQKIQDRFEADFVQYLQLAKATTDEASASSQQAYGWSIWLVAGAVLMLLVVTLSAMWWLRTMLVQPLNIIRGHFERIASGDLSAPIEVYGRNEISQLFASLQRMQQSLIGTVGAVRDGAESILIGLQEIAEGNNDLSSRTEQQAASLEETAASMEQLTATVKQNADNARQASQLARDASSTAAKGGELADDVVTTMHDIANSSQKIGAITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKLLIDESVSRVKHGSVLVENSGATMQDIVRSVTRVTDIMGEIASASDEQSRGIEQVTQAVTQMDQVTQQNAALVVESASAAAALEEQAITLADAVAVFRLADDNFVAPETSSTVKETLDCQTA
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.  Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
What are the official names of this protein?
Methyl-accepting chemotaxis aspartate transducer.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADDA_GEOTN
Sequence: MNATFRPKPAGSRWTDEQWKAIAAGGRDILVAAAAGSGKTAVLVERIIQKVTAEEGAVDIDRLLVVTFTNAAAAEMKARIGEALERELANRPHSLHLRRQLSLLNRASISTLHSFCLDVIRKYYYLLDLDPSFRIADETEIELLKEDVLEELLEEEYGKADNERFFAVVDAYTGDRSDAELQEMILALYEFSRSHPAPDEWLADLVSMYDVDEQTNVETLPPARYIAQHAAMELAAAKRFIGLALALAEKESGPKPYEKRLREDMDLIADLERRLSGSWDELYHALQSLSFGRLPPCRGDGFDAELIDEAKSLRDQAKKKIEALRDNVFSLHPSAWLRHMREMKPVVETIAALVRRFSAMFEAAKREKGIVDFSDLEHYCLRILRQYDPETGEWQPSSAALEYQAQFDEVLVDEYQDTNLVQETILQLVKKGSERTGNLFMVGDVKQSIYRFRLAEPMLFLDKYKRFTADGEAGGMKIDLASNFRSRAEVLDGTNFLFAQIMGEAVGEMVYDEAAQLKYGADYPEGTDAVPEVMIIDRQRTSEEDEEETAELEAAELESRLMAEKIKEIVSRPFYVYDRSSGQQRRAMYRDIVVLVRSMTNAPQMIEQLQAQGIPAAADLSSGYFQATEISVMLSLLKVIDNPYQDIPLAAVLRSPLFRFDENELAMIRLSDPKGTFFEALQAFCQKTAETGEEENAKEKAISFLNKLEEWRTMARRRSLADLIWQLYRDTQFYDFVGALPGGKQRQANLRALYDRARQYESTSFRGLFRFLRFIERLQERGDDLGAARPLGDQEDVVRVMTIHSSKGLEFPIVFLVGLARPFYTRDLHSPYLLDKELGFAARFVHPRLRISYPTLPLLAIQVKKRLELLAEEMRILYVALTRAKEKLYLLASVNDADKEIEKWKGVAAESGWLLPDDVRASARSYLDWIGRALIRHRDGRSLVEVNRPDEIASHPSVWRFEIVSAAKLRNAEVSTDREDGGALVALEQGRPVPTQGEWEEEARRRLLWRYRYGKETVVRAKQSVSELKEQQALFGEQADEWLPRKGTAPLFSRPRFMQEKTLTPAEKGTALHVVMRHLDLHAPMDESSIRSQIIRLVEKELLSAEQAETVDAAAIVAFFATDIGRRLCAAREVYREVPFSLGLPADELYGSEGMESGRRLLVQGVVDCVFADERGYVVIDYKTDEVTGRFAGQKEEATRFLLGRYGGQMRLYRRAIEQIWRVPVAECYLYSFDGEYFLAVE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: RLMM_SHEB9
Sequence: MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDLPENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVGYSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDNGPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILETMQTILKENGVSDFKVQCKHLYHDRDEVTVHLWLRPNTAWN
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_GLUDA
Sequence: MPLFNMHQIRGQLGRDQRLLGLDPGQKTIGLALSDVSLMLASPYGALRRGKLSVVAAEIRRIAAREGVGGLVSGLPLSMDGSFGPAAQAARDWMISLSEQVGLPAAMWDERLSSSAVNRMLIQDADMTRQRRAELVDKLAASYMLQGALDATAE
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSB1_ARATH
Sequence: MNTFFKLGSLIQRTASQISSSFPKSRFFSDGESAVYHHARLFKKPLSTKLKFNLVNSVSLMGFVDRSIQVMNTGPDRFGVFTILRVKDPLNPNRSFRISLRMWDAMARTCIAHLKLNDHILVSGRLESYSKSSSDVYSGLNLDYQVKVAEVNYVAAPPSHVLDSQISKNPKTKTEDDIEESKKDEIYLWQVFFSNPYDWWDNRRNKKNPKQPDFKHKDTGEALWLCSDLPDWITRRLELFDQKNRFYDEEKTRRDRLSDYI
What is the function of this protein?
Regulates mitochondrial DNA recombination.  Represses homologous recombination, preventing mitochondrial genome instability and unbalanced transmission of alternative mtDNA configurations.  Binds preferentially single-stranded DNA.  Does not bind to RNA.
What are the official names of this protein?
Protein OSB1, mitochondrial, Organellar single-stranded DNA-binding protein 1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y3391_BURL3
Sequence: MCHAAPARPGDGRGLPRAGDNFSGAARSKPVGAAFEQRARQFLERRGLVFVAANVTMRGGELDLVMREPDGMLVFVEVRARRSARHGGAAASVGWRKRRRLVAAALQFWARHGAGAACRFDVVAFEAGQLAWLRDAFRADDA
What are the official names of this protein?
UPF0102 protein Bcep18194_A3391.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: EFGM_AEDAE
Sequence: MTISSFLRVRHSLAAAKCVLENAKQSFSSHAAFAEHAKLERIRNIGISAHIDSGKTTLTERILFYTGRIKQMHEVKGKDNVGATMDSMELERQRGITIQSAATYTMWKDHNINIIDTPGHVDFTVEVERALRVLDGAILVLCSVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRTGANPYRVLGQMRSKLNHNAAFIQLPIGVESNCKGIVDLVKQRALYFEDHLGLTVREDEIPQEMRAESDERRHELIEHLSNVDESIGELFLEEKTPTEQDIMAAIRRSALKRTFTPVLVGTALKNKGVQPLLDAVLNYLPHPGEVENIALIEKKGKEPQQIMLDPARDGKSPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDSIFNVRSGKKVRLARLVRLHSNNMEDVNEVYAGDIFALFGVDCASGDTFVTNPDLELSMESIFVPDPVVSMAIKPANNKDRDNFSKAVARFTKEDPTFRFAYDTDIKETLVSGMGELHLEIYAQRMEREYNCPVILGKPKVAFRETLVAPCEFDFLHKKQSGGQGQYARVTGVLEPLPPHQNTTIEFTDETVGTNVPKQFVPGIEKGFRQMAEKGLLSGHKLSGIKFRLQDGAHHIVDSSELAFMLAAQGAIKSVFENGSWQILEPIMMVEVTAPEEFQGTVIGQLNKRHGIITGTEGSEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFSMEYSRYSPCKPDVQEKLMQDYQIAQGNVVVDAKKQQKKKN
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TIMP1_HUMAN
Sequence: MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRSQIA
What is the function of this protein?
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor.  Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16.  Does not act on MMP14.  Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1.  Plays a role in integrin signaling.  Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
What are the official names of this protein?
Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: F16PA_SHEB9
Sequence: MQTLTQHLTSQAVNDSLSHLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRGLASEEEDHVVEVRQNGQYLVCFDPLDGSSNIDINSLVGTIFSILPAPAGELTETSFLQSGRAQLAAGYVLYGPSTMLALTTGQGVQLFTLDPETNEFLLTNAAMSISPETQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHRVLSRGGIFTYPSDNKDPKKPYKLRLMYEANPMAFLVEQAGGKASTGYETILDITPTHIHQRVAVILGSANEVDACLSYHGIDSHK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_STRPJ
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHLRKASMVHSGDYKRIKAMLTRLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: HSP1_PSENI
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHRNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FUTA1_SYNY3
Sequence: MVQKLSRRLFLSIGTAFTVVVGSQLLSSCGQSPDAPIADTPGEQQEINLYSSRHYNTDNELYAKFTAETGIKVNLIEGKADELLERIKSEGANSPADVLLTVDLARLWRAEEDGIFQPVQSEILETNVPEYLRSPDGMWFGFTKRARVIMYNKGKVKPEELSTYEELADPKWKGRVIIRSSSNEYNQSLVASLVVADGEESTLAWAKGFVSNFAREPQGNDTAQIEAVSSGEADLTLANTYYMGRLLESEDPAQKAIAENVGVFFPNQEGRGTHVNVSGVGVVKTAPNREGAVKFIEFLVSEPAQAFLAQNNYEYPVLAGVPLNKSVASFGEFKSDTTSLDKLGPALAPATKIMNEAGWK
What is the function of this protein?
A major iron-binding protein involved in Fe(3+) uptake, probably part of a periplasmic ABC transporter complex futA1A2BC (TC 3. A. 1. 10. 2) involved in Fe(3+) ion import (ferric iron).  This protein and futA2 (slr0531) may be subunit proteins that have redundant or overlapping substrate-binding functions (Probable).
What are the official names of this protein?
Iron uptake protein A1.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Lipid- anchor. Cell membrane; Lipid-anchor. Note=Localization to the periplasm was not detected in PubMed:12368463.
Protein: MURB_CLOB6
Sequence: MNQYKNFIMQFEDIVGNNNVLIDEPMKKHTSFKVGGPADLLITPTTLEQVKDSIILCRNNSIPYYIIGNGSNLLVRDGGIRGVVIKFLKLGDIKVEVDRVIAQSGAPLTNICNEALKSNLGGLEFACGIPGSVGGAVTMNAGAYNGEISQVIESAKVIDKDGNVFLLNKEQLDLGYRMSAIQKYHYIVLEVTFKLHNSEYDTIKNRIMDLNRRRTEKQPLEYPSAGSTFKRPEGHFAAKLIEDTGLKGKSIGGAQVSEKHSGFIINKGGATAGDILNLIEFVQNKVKEKFQVDLHTEVRIIGEENN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_YERPY
Sequence: MALERTFSIIKPNAVANNNIGAIYARFESAGFKIIAAKMLHLTKEQAEGFYAEHKGRPFFDGLVEFMTSGPIIVQVLEGENAVQRHRDIMGATNPDNALAGTLRADFADSFTANAVHGSDAVESAQREIAYFFAADEIFPRS
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_BARHE
Sequence: MGLIVYYSSATGNTEYFVSQLDQRLFKIDKKKPSMLVDEPYVLVVPTYADGEGKMAVPKAVIRFLNEDENRKLIRGVIGGGNRNFGRYYSLASKIIAEKCFVPCLYRFELRGTEEDIICVKKGLERFWKQLV
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: RECF_RICRS
Sequence: MKNIFLHSLSLENYRNFKNLELKTDNTPIILIGENGSGKTNILEAISLFYPGRGLRSAKLANVCKTSEDHCLVKALLQSKLGLAEFTTQFKRSSNRRITEYNESKIANNELSKFTSMVWLTPHMEGIFTSGSNDRRKFLDRIVYNFDPKHAELVSKYEYYMHERNKILVEDIRDDNWLKIIEEKMADISNHIANNRLKTLEFMQQAIDDLENEFPKADLSIDGIVEQKILNGKENIVSFITAELYQTRSKDKLLGRTSFGVHKSDFLVKHQKKNILAKFCSTGEQKAILIAIILAEMNYAIKLTKIAPILLLDEVFVHLDDKRRQYLIEFLTGLNMQLWVTTTNLEGIENFANKAQLIKL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.