PharMolix/UniProtQA huggingface dataset:
Protein: AGO_MARPK
Sequence: MYLNLYKIDIPKKIKRLYFYNPDMEPKLFARNLSRVNNFKFQDSNDLVWIEIPDIDFQITPKNVFQYKVEKEEIIKEEEDKKLFVKTLYKYIKKLFLDNDFYFKKGNNFISNSEVFSLDSNENVNAHLTYKIKIHNISNEYYLSILPKFTFLSKEPALESAIKSGYLYNIKSGKSFPYISGLDGILKIDIGNNQIVEVAYPENYLFNFTTRDAEKYGFSKEVHEIYKNKVFEGFKKIPKTLGFLNKITNLNENYQLKDGYKIFINVIYKFKNGESRYAKDVFKYSFYKNEQPLKAIFFFSSKKQFFEVQKSLKELFHNKHSVFYRAAAELGFSKVEFLRDSKTKSSAFLYNPEEFTVKNTEFINQIEDNVMAIVLLDKYIGNIDPLVRNFPDNLILQPILKEKLEDIKPFIIKSYVYKMGNFIPECKPFILKKMEDKEKNLYIGIDLSHDTYARKTNLCIAAVDNTGDILYIGKHKNLELNEKMNLDILEKEYIKAFEKYIEKFNVSPENVFILRDGRFIEDIEIIKNFISYNDTKYTLVEVNKNTNINSYDDLKEWIIKLDENTYIYYPKTFLNQKGVEVKILENNTDYTIEEIIEQIYLLTRVAHSTPYTNYKLPYPLHIANKVALTDYEWKLYIPY
What is the function of this protein?
An RNA-guided ssDNA endonuclease that may play a role in defense against invading mobile genetic elements.  Uses short 5'-OH-ssRNA sequences as guides (gRNA) to bind complementary target DNA (tDNA) or target RNA resulting in target cleavage.  The cleavage site is 10 nucleotides (nt) downstream of the target residue base-paired with the 5'-end of the gRNA.  Reaction rates are fastest on 5'-OH-gRNA:tDNA followed by 5'-OH-gRNA:target RNA.  gRNA between 17-21 nt supports equivalent rates of cleavage, has no preferred 5'-nt.  Has weak activity on tDNA with 5'-phospho-gRNA, yielding products 1-2 nt longer (PubMed:27035975).  Unlike other characterized prokaryotic Ago proteins symmetric mismatches centered around the cleavage site reduce cleavage efficiency (PubMed:28520746).
What are the official names of this protein?
Protein argonaute, MpAgo.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Long pAgo subfamily.
Protein: DUT_SIRV1
Sequence: MILSDRDIKTYINSKKLVINPLSEDTIRENGVDLKIGNEIVRIKENMEKEVGDEFIIYPNEHVLLTTKEYIKLSNDIIAFCNLRSTFARKGLLIPPTIVDAGFEGQLTIELVGSSIPVKLKSGERFLHLIFARTLTPVEKPYNGKYQKQKGVTLAKED
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.  It does probably not deaminate dCTP.
What are the official names of this protein?
Probable deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: VM2OI_ECHOC
Sequence: DCESGPCCDNCKFLKEGTICKMARGDNMHHYCNGKTCDCPRNPYKGEHD
What is the function of this protein?
Inhibits ADP-induced human platelet aggregation.
What are the official names of this protein?
Disintegrin ocellatin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL22_CAUVC
Sequence: MAKQKQERRLPAAEAMCKVRTLRTSPRKLNLVAQSIRGLNVQRALNELEFSHKRIAQDVRKALYSAISNAENNHNLDIDSLVVAEAYVGKNLIMKRFSPRARGRATRVEKPFSEITIVVRELGEAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL6_PROMH
Sequence: MSRVAKAPVVIPAGVEVKLNGQVITIKGKNGELTRTIHNAVEIQHADNQLTFAPRDGYADAWAQAGTTRSLLNAMVVGVTEGFTKKLQLVGVGYRASVKGNTVNLSVGYSHPVEHQLPAGITAECPTQTEILLKGADKQVIGQVAAELRAYRRPEPYKGKGIRYADEVVRIKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: IWS1_YEAST
Sequence: MSTADQEQPKVVEATPEDGTASSQKSTINAENENTKQNQSMEPQETSKGTSNDTKDPDNGEKNEEAAIDENSNVEAAERKRKHISTDFSDDDLEKEEHNDQSLQPTVENRASKDRDSSATPSSRQELEEKLDRILKKPKVRRTRRDEDDLEQYLDEKILRLKDEMNIAAQLDIDTLNKRIETGDTSLIAMQKVKLLPKVVSVLSKANLADTILDNNLLQSVRIWLEPLPDGSLPSFEIQKSLFAALNDLPVKTEHLKESGLGRVVIFYTKSKRVEAQLARLAEKLIAEWTRPIIGASDNYRDKRIMQLEFDSEKLRKKSVMDSAKNRKKKSKSGEDPTSRGSSVQTLYEQAAARRNRAAAPAQTTTDYKYAPVSNLSAVPTNARAVGVGSTLNNSEMYKRLTSRLNKKHK
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.
What are the official names of this protein?
Transcription factor SPN1, Interacts with SPT6 protein 1, Suppresses postrecruitment functions protein 1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MCBA_ECO57
Sequence: MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATGASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTATIYK
What is the function of this protein?
Affects biofilm formation and mucoidy.
What are the official names of this protein?
Uncharacterized protein McbA.
What is the protein family that this protein belongs to?
Belongs to the BhsA/McbA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KIFA3_HUMAN
Sequence: MQGEDARYLKRKVKGGNIDVHPSEKALIVHYEVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLARKVVEECKLIHPSKLNEVEQLLYYLQNRRDSLSGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGLITHYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDPENQTLRKDYEKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNDNYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFECSDERIDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPYLKDKLKPGAAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDESEQYLYGDDRIEPYIHEGDILERPDLFYNSDGLIASEGAISPDFFNDYHLQNGDVVGQHSFPGSLGMDGFGQPVGILGRPATAYGFRPDEPYYYGYGS
What is the function of this protein?
Involved in tethering the chromosomes to the spindle pole and in chromosome movement.  Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex (By similarity).
What are the official names of this protein?
Kinesin-associated protein 3, KAP-3, KAP3, Smg GDS-associated protein.
Protein: MFR1_SCHPO
Sequence: MGDRFIPIRNVSNEFNFSFQSFKECVLSHGSNLRRKTSGTIQRQFMELLSMELFGSQASRSRAFYYGEDKRKIEKKMLDTPDRKSYSLSPISPQSQDMLRQPQKPKRAFPKTPYKILDAPYLKNDFYLNLLDWGQSNVLAVGLASSIYLWSAASGKVVQLHDFGATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAWNDNTLTSGGKDEVILHHDLRAPGCCAEMMKVHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFEEHTAAVKAIGWSPHQRGILASGGGTIDRCLTIHNTLTGRLQNKLDTGSQVCNMAWSKTSNEIVTTHGFAKNQVSLWKYPSLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKLFNKKPKEESTLIR
What is the function of this protein?
Meiosis-specific activator of the anaphase promoting complex/cyclosome (APC/C).  Involved in cdc13 degradation.
What are the official names of this protein?
Meiotic fizzy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CDC20/Fizzy family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CMOA_SHEHH
Sequence: MNSSTDNLFAKPYEQVSDFQFDDKVAGVFNDMIRRSVPGYGQIINTIGDLAQKYAATNTKIYDLGCSLGAATLSIRRRVEGRNCQIVAIDNSESMIERCNENLSAYVSETPVELICGDIRDIKIENASLVVLNFTMQFLSPDDRENLLENIYQGLIPGGLLILSEKLYFKEDKIQSTLDDLHLDFKRANGYSELEISQKRSSLENVMKPDTLAEHENRIRSLGFSQFSVWFQCFNFASMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: ASTI_ASPOR
Sequence: MTRQSHYQAIILDLGNVVFEWDTSQNPPTAAPNQISLLRTSMKSPVYHSYERGQLSTEECHRLLGESLHVDPGQIKEAFDLARQSLRSNPALLDFIRQLKQTRGVAVYAMSNIPQAEIEYLKESRAGDMEVFDEVFASGYVGSRKPETEFYRRVMGEIGLKAERVVFVDDKEENVDVARGLGLYGVCFGGVEELRGHLLGI
What is the function of this protein?
Sesquiterpene phosphatase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599).  The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599).  Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599).  Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599).  The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599).  The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599).  Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).
What are the official names of this protein?
Sesquiterpene phosphatase astI, Astellolide biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: DELT_PHYBU
Sequence: YMFHLMN
What is the function of this protein?
Has a very potent opiate-like activity.  It has high affinity and selectivity for delta-type opioid receptors (By similarity).
What are the official names of this protein?
Deltorphin-like peptide.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermorphin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AP180_ARATH
Sequence: MPSKLKKAIGAVKDQTSISLAKVANGATGGGDLTTLEVAILKATSHDEEVPIDDRLVTEILGIISSKKSHAASCAAAIGRRIGRTRNWIVALKSLVLVLRIFQDGDPYFPREVLHAMKRGAKILNLSSFRDDSNSCPWDFTAFVRTFALYLDERLDCFLTGKLQRRYTNREQTGRISTNSTTRSRFNPKAGIKSHEPAVRDMKPVMLLDKITYWQKLLDRAIATRPTGDAKANRLVKMSLYAVMQESFDLYRDISDGLALLLDSFFHLQYQSCINAFQACVRASKQFEELNAFYDLSKSIGIGRTSEYPSIQKISLELLETLQEFLKDQSSFPASSGLYPSPNSFLPPPPSSKDSAVSSSLDFGDSTIDTSERYSDYGSFRSTSLEDLMSRTEAGTSSPPMSCHSEPYGGGRDDPNGNNFDTVSTKSLPNNPSVSASNLILDLLSLDDVSNTAEAEDVEDKKKQDDSKAETFDPWEALMLRDDPKKKIETIEEEPSTAEDHQRDSGNWLLALEETATQVQGNNSMAIVPFGLDDPMPAFQAATDQYNPFLEEPVAQLATAGEPMITFGGLALTGFQPEPTFQVNVPDDFEPSSTPTFKATETLPMKCDPFTTFESFGFGETFSENGGVNQQSVLQEQQIWLQNQKKIIAKHLS
What is the function of this protein?
Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  Binding of AP180 to clathrin triskelia promotes their assembly into 70-90 nm coats cages.
What are the official names of this protein?
Clathrin coat assembly protein AP180, At-AP180, Clathrin coat-associated protein AP180.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.
Protein: FTSZ_CORGL
Sequence: MTSPNNYLAKIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGREATRGLGAGANPEVGRASAEDHKNEIEETIKGADMVFVTAGEGGGTGTGAAPVVAGIAKKMGALTIGVVTKPFEFEGRRRTRQAEEGIAALKEVCDTLIVIPNDRLLELGDANLSIMEAFRAADEVLHNGVQGITNLITIPGVINVDFADVRSVMSEAGSALMGVGSARGDNRVVSATEQAINSPLLEATMDGATGVLLSFAGGSDLGLMEVNAAASMVRERSDEDVNLIFGTIIDDNLGDEVRVTVIATGFDAARASAAENRRAGISAAPAAEPVQQQVPTTNATLPPEKESIFGGAREENDPYLSRSAGARHRIEETRSGGGLFTTGNDRDYRRDERREDHRDERRDERRDDRSYDRRDDRRDDRRDDRGDDLDVPSFLQ
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: CYB_CERSI
Sequence: MTNIRKSHPLIKIINHSFIDLPTPSNISAWWNFGSLLGICLILQILTGLFLAMHYTPDTMTAFSSVAHICRDVNYGWIIRYLHANGASMFFICLFIHVGRGIYYGSYTFLETWNIGVILLFTLMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMALAITHLLFLHETGSNNPSGIPSNMDKIPFHPYYTIKDILGILLLILALLALVLFSPDILGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILTLLIIPFLHTSKQRSMMFRPLSQCMFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTLILVLMPLAGIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y107_MYCPN
Sequence: MTNQNLQDFLDGVLLKEENLNKITEVSLEKGLPHLLDEGIHNEDNFQIFTSQKIVADMIKMVGVKEMKNVHTTVLEPTSGDGAFTCAILDLRLKNIKKSDSFLKEALTGLSTIYSVEIDEELVWLQRNNLYSIFLAFLKKHGIFNEELSLLVKKILMINVSWGELITETKDNENFVCNYDYFLRNKKTKKKPAKHKHEFPEGLFSNGEGKCKSLFVNWSFADVINEIAHNSNFYFAKIAKIPGEIIQFQIN
What are the official names of this protein?
Uncharacterized protein MPN_107.
Protein: PA2A2_TRIGA
Sequence: NLLQFENMIRNVAGRSGIWWYSDYGCYCGKGGHGRPQDASDRCCFVHDCCYGKVNGCNPKKAVYIYSLENGDIVCGGDDPCRKEVCECDKAAAICFRDNKDTYDNKYWNIPSENCQEESEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that has high lipolytic activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 2, svPLA2, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 isozyme II, PLA2-II.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ADCK1_CHICK
Sequence: MARRALKLASLAAAASGIYLYGNKFMDPNDFGVVRVGRAIATTAVITYDYLTSLRNVPYGSEEYDFLKSQVHLRSAERLRELCCANRGTFIKVGQHLGALDYLLPEEYTRTLKVLHSQAPQSTRQEIEQVIREDLGKEIKELFVSFEDTPLGAASLAQVHKAVLQDGRTVAVKIQHPKVQAQSSKDIFLMEVLLLVVKQIFPDFEFMWLVEEAKKNLPLELDFLNEGRNAEKVAQMLKNFEFLKVPRIYWELSTRRVLLMEFMEGGQVNDKAYMEKNGIDVNEISRNLGKLYSEMIFVNGFVHCDPHPGNVLVKKCPDSGKAYIILLDHGLYQVLSESFRMDYCRLWLALIKADMKRVQKYSRRLGAGDLYPLFACMLTARSWESVNRGIDQSPVSASEDVEIRSNAAAYLPQITQLLNNVPRQMLLLLKTNDLLRGIESALHTRASASSFLNMSRCCIRAVSTYQRSKSHSLYRRVHISLTEALSLWQINLYELFLWLKGSRLGSWVIAFLSRMHHST
What is the function of this protein?
Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (By similarity).  The action of this enzyme is not yet clear.  It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable).
What are the official names of this protein?
AarF domain-containing protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYT_RUEST
Sequence: MAQISLTFPDGNARSYDAGITPAEVAADISTSLAKKAISATVDGQHWDLQWPVTQDAAIAIHTMKDEAQANELIRHDLAHIMARAVQEIWPDTKVTIGPVIENGWYYDFDRAEPFTPEDLGTIEKKMKEIINKREPVTTEVWEREKAIQYYTDNNEPYKVELIDSIPGDEPLRMYWHGDWQDLCRGPHLQHTGQVPGDAFKLMSIAGAYWRGDSDRQMLQRIYGVAFTGKEKLKAHLTMLEEAAKRDHRKLGREMNLFHMQEEAPGQVFWHPNGWRIYTTLQDYMRRMQDRDGYVEVNTPQVVDRKLWEKSGHWDKYQENMFIVEVDEDHAREKAVNALKPMNCPCHVQVFNQGLKSYRDLPLRMAEFGSCARYEPSGALHGIMRVRGFTQDDGHIFCTEDQITSETAKFIAFLSKVYADLGFDNWTIKLSTRPEQRIGSDETWDNMEQALGDACKAAGYDYEILEGEGAFYGPKLEFTLTDAIGRNWQCGTLQVDANLPERLEASFIGQDGSKHRPVMLHRATLGSFERFIGILIEEHAGKLPFWLAPRQVVVASITSEADDYVNEVVETLRAAGVRAEADTRNEKINYKVREHSVGKVPVILAVGHREVEERTVSVRRLGEKQTKVESLTNVTEELAKAATPPDLL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CENPH_BOVIN
Sequence: METQSEEQAVTKPADSGGEGGPPQVAGAQAARPEDRMTLLLRLRAQTKQQLLEYKSMVDANEEKTPEQIMQEKQIEAKIEELENEVEEAKTAFEMKKLALDRMQLSTALKKHLEKVDIKTSVLMDNMKQILNLNKLIMKSQQETWDLEEKLLDVRKKRLQLKQASERKLLEIQTEKNKQKDDLDSMENSDKIKAIQQNLETEIQITTVIQHVFQNLILGSKVNWAEDPALKETVLQLEKNLTMI
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity).
What are the official names of this protein?
Centromere protein H, CENP-H.
What is the protein family that this protein belongs to?
Belongs to the CENP-H/MCM16 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associates with active centromere-kinetochore complexes throughout the cell cycle. Colocalizes with inner kinetochore plate proteins CENPA and CENPC during both interphase and metaphase (By similarity).
Protein: CODY_BACCQ
Sequence: MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLFNITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLHELAKLKTN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_RHOPB
Sequence: MDAKTDDKAGKCPVAHGPAPRGNRDWWPEQLNLSMLHQRSPSADPLGKDFHYAEQFKTLDLKALKQDLTALMTESQDWWPADFGHYGGLFIRMAWHSAGTYRTTDGRGGAGAGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGQKISWADLYVLAGNVALESMGFQTFGFAGGRADTWEPEELFWGPEGTWLGDERYSGERQLADPLGAVQMGLIYVNPEGPNGNPDPLGSAKDIRETFARMAMNDEETVALIAGGHTFGKTHGAGDPSLLGPEPEGGDVEDQGLGWKSKYGTGFGADAITGGPEVIWSQEPTKWSNHFFDNLFKFEWELTKSPAGAQQWVAKNAEPSVPDPFDPSKKRLPTMLTSDLALRFDPIYEKISRRFYENPDEFADAFARAWFKLTHRDMGPVARYLGPEVPKETLLWQDPIPPVDHELINDADVEALKAKILGSGLSVADLVSTAWNSASTFRGSDKRGGANGARIRLAPQKDWEVNQPEQLATVLQKLEAIGKEFGKKVSLADLIVLGGVAAIEKAAKDAGVAVKVPFSPGRMDASQEQTDAPSFAPLEPRADGFRNYINSKKHQFMKPEEALVDRAQLLTLTAPEMTVLVGGLRVLGANAGDSKHGVFTTKPGTLSNDFFVNLLTMATSWQPSGTEGIYEGRDRKSGEVKWTATRVDLIFGSHSQLRALAEVYAQADSKEKFVNDFVAAWTKVMNADRFDLIAEPVLLEAAE
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: TLP_ORYSJ
Sequence: MASPATSSAVLVVVLVATLAAGGANAATFTITNRCSFTVWPAATPVGGGVQLSPGQTWTINVPAGTSSGRVWGRTGCSFDGSGRGSCATGDCAGALSCTLSGQKPLTLAEFTIGGSQDFYDLSVIDGYNVAMSFSCSSGVTVTCRDSRCPDAYLFPEDNTKTHACSGNSNYQVVFCP
What are the official names of this protein?
Thaumatin-like protein.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NEUFC_XENTR
Sequence: MLGYLAAAALCLAAVLLMRLDHLPLVDIPGLGYIFPQQCELSEGRLMSKEELSVYDGGPGSSGIYLAILGQVFDVHKGSKHYGPGGSYSFFAGKDASRAYMTGDFTEKGLVDDVTELSPLQMLHLHNWLSFYQQNYITIGKLTGRFYDESGNPTKALEDALKVIDIGLKLKEEREEENKQFPPCNSEWSSESKRVWCSKNSGGIQRDWVGVPRKMYTAGTNGYRCVCVRNFGPPSEQPDSTEHNDRGDLDNPMLHEYEDCNPLFEWCFLKNGT
What is the function of this protein?
Heme-binding protein which promotes neuronal but not astrocyte differentiation.
What are the official names of this protein?
Neuferricin, Cytochrome b5 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EAMB_SALTI
Sequence: MTPMLLSAFWTYTLITALTPGPNNILALSAATAHGFRQSIRVLAGMSLGFLVVMLLCAGIAFSLAVIDPAIIHLLSWVGAAYILWLAWKIATSPAADEKVRPKPVGFWVSFGLQFVNVKIILYGITALSTFVLPQTQALNWVIGVSILLALIGTFGNVCWALAGHLFQRAFRHYGRQLNIILALLLVYCAVRIFY
What is the function of this protein?
Exporter of O-acetylserine (OAS) and cysteine.
What are the official names of this protein?
Cysteine/O-acetylserine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMA_SERMA
Sequence: MKLNKIMLATVLAFGVSSLANAADQGHGKVTFTGSIIDAPCSIAPESADQTVEMGQISNVALKNGGKSAPRQFDIKLEQCDTSTLKTVTTTFDGKASAANPDLLGIIGTASGASIAITDMASNPIKLGTATAPQTLNDGNNTLRFAAYLQGDGASATVVPGDFTAVADFKLAYQ
What is the function of this protein?
Major structural component of mannose-resistant fimbriae of Serratia marcescens.
What are the official names of this protein?
Fimbria A protein.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: DEOD_LACLA
Sequence: MPTPHIEAQKGEIADKILLPGDPLRAKFIAENFLEDAVQFNQVRGMLGFTGTYKGHRVSVMGTGMGIPSISIYANELITEYGVKRLIRVGTAGSVNEDVHIRDLVIGQAAATTSAIIRNDFPDFDFPQIADFDLLDKAYHIAKDLGITTHVGNILSSDLFYGGPDAVKVGKLGVKAVEMEAAGLYYLGAKYKVQTLGIMTISDHILTGESTTSEERQLTFTDMMKVGLETLISE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.