PharMolix/UniProtQA huggingface dataset:
Protein: PGLRD_ASPOR
Sequence: MKRSALILSFLPLVFGCDNPKSPGHSCASVYSVSSAAASSFCATFTASTVTATTGVPEALLSNCDYKTKHLSSACSCLGTAAVPTVATPSSVSSVYITSATATPTSFTFKTSTAHIVKVAKAATSSTAVVTTPVSVPTASSSFTGNGGTTCTVTEYAAISSAVASCSNILLSDIYAPPSSTIDLQGLQTGAAVIFAGKTTFGDTADSDFDPIVVSGTSVTITGVEGHVIDGNGAAYWDGQGSNGGSDKPDHFFVVKDMYNSRIENLYIQNWPVHCFEIESTEHLTVSGLTLNNSAGDAANSKSDGDPAAHNSDGFDIKESSYFTLENTWVHNQDDCVAVTSGTDIVVDGMYCYGGHGLSIGSIGGKSDNTVNGVTFSNSQVISSQNGCRIKTNSGETGEVYNIRYENITLSDISDYGIDVQQDYLNGGPTGEPTNGVTIANVTFVDVTGTMSDGKDYYILCGDDSCSNFVFDGVSITGGSGDSCNYPSTGCP
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase D, PGD, Pectinase D, Polygalacturonase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIG_MYCA1
Sequence: MVDSKLTIADRSFSSRLIMGTGGAGNLAVLEEALIASGTELTTVAIRRVDAEGGTGLLDLLNRLGITPLPNTAGCRGAAEAVLTAQLAREALNTNWIKLEVIADERTLLPDAVELVRAAEQLVDDGFVVLPYTNDDPVLARRLEDAGCAAVMPLGSPIGTGLGITNPHNIEMIVAGAGVPVVLDAGIGTASDAALAMELGCDAVLLATAVTRAGDPAAMAAAMSAAVTAGYLARRAGRIPKRFWAQASSPPR
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_CLOB6
Sequence: MNQFKVISKFNPTGDQPKAIKSIAKGIEKGEKFQTLIGVTGSGKTFTMANIIEKAQKPTLVLAHNKTLAAQLCSEFREFFPNNAVEYFVSYYDYYQPEAYVAQSDTYIEKDASINDEIDKLRHSATSALFERKDVIIVASVSCIYGLGNPEEYKKLTISLREGMEKDRDEIIKKLVEIQYERNDIDFSRGTFRVKGDVLDIFPASSSSKAIRVEFFGDEIDRIKEFDVLTGETITKLKHISIFPASHFATSKDRLEIAIKNIEEELEERVKELVSQDKILEAQRLKQRTNFDIEMMREVGYCTGIENYSRVLDGRAKGTPPQTLLDYFPQDFLLFIDESHVTLPQVKAMQAGDKSRKDSLVEYGFRLPCAYDNRPLTFKEFENKLNQIVFVSATPAKYELEYSTNTAEQVIRPTGLLDPEIIVKPVKGQIDDLYTSIQETIKKGFRILVTTLTKKMAEDLTDYLKEMGVKTRYLHSDIDTIERMKIIHDLRKGEFHVLVGINLLREGLDIPEVALVTILDADKEGFLRSETSLIQTVGRAARNSESKVIMYGDVITKSMEKTIKETNRRRKIQMEYNEKHGIVPKTIIKDIREVIQISDIAEERKEYDNLNEALKSYNNDIDKLIEKYEEEMREAAQNLQFEKAAHLRDVIYKLKRDKETEL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_TOLAT
Sequence: MQVSVETTQGLERRLTITVPADKIEKEYNSRLNQVAKTRRIDGFRPGKAPKALIQKMYGESIVADVADAVMQRHFVEALVAEKLNPVGAPTLEPNQLVPGSDFTFTVSFEVYPEFKVQNLDAIKVEKPVATVSDADLDKMLTTLRKQHASWVDADEAAANDLRVNMDFVGSVDGEEFEGGKAEGFALVLGAGRMIPGFEAGILGKKAGESFDIEVTFPEDYHAENLKGKAAKFAIKLNKVEKQDLPELDAEFIKRFGVEDGSVESLKAEIRKNMERELTQALKGQVKEQILSGLLEQNLIDVPKAAVTREVEALRQQALQRFGAANSKNVPQLPDELFQEQAERRVRVGLLLGEVIREQDIKADDARVKTLIESLATAYEDPSEVVDYYFQNERLLNNMRDLAVEDQAIEFLLSQAQVTEKATSFDEVINKAGAAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: E4PD_PECCP
Sequence: MTIRIAINGFGRIGRSVLRALYESGRRAEITVVAINELASAEGMAHLLKYDSSHGRFSWDVRQECDQLYVGDDCIRLLHQAEIQALPWRELGVDIVLDCSGVYGSREDGEAHLAAGAKKVLFSHPGTADLDATVVFGVNHQQLEREHRIVSNASCTTNCIIPVIKLLDDAFGIENGTVTTIHSSMNDQPVIDAYHHDLRRTRAASQSIIPVDTKLSAGITRIFPQFVDRFEAISVRVPTINVTAIDLSVSVRKAVNVNEINALLQKSAHESFRGIVDYTELPLVSADFNHDPHSAIVDGTQTRVSGQHLIKTLVWCDNEWGFANRMLDTTRAMAACGF
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLSA_SHIBS
Sequence: MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAPLFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEIVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQDDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECF_FLAPJ
Sequence: MYLKKISLFNFKNFSDTSFNFEHKINCFVGKNGVGKTNVLDAIYHLSFGKSYFNTLAVQNIKHDEDFFVIDGEFDKQERSENILCSLKKGQKKILKRNGKIYEKFSDHLGFIPLVIISPTDADLIREGSETRRKFIDSVISQLDNQYLQGLILYQKVLSQRNALLKYFAVNRIFETGTLDIYNEQLNDLGQSIFEKRKQFLNDFIPIFNSFYQNISNSAETVQLEYESQLEKQDLLSLLQENINKDRSLQYTSVGVHKDDLSFNIAHYPIKKFGSQGQQKSFLIALKLAQFEFVKKQSGEKPILLFDDIFDKLDETRVEKIVAMVNNDDFGQLFISDTHSQRTENIVKMTHQSYKIFNL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF2_PYRAB
Sequence: MGRREEMIAKIKELMLQPERIRNIGIAAHIDHGKTTLSDNLLAGAGMISEELAGKQLVLDFDEQEQARGITINAANVSMVHNYEGKDYLINLIDTPGHVDFGGDVTRAMRAIDGVIIVVDAVEGVMPQTETVVRQALREYVKPVLFINKVDRLIRELKLTPQQMMERFSKIIMDVNRLIQRYAPEEYKKQWMVKVEDGSVAFGSAYYNWALSVPFMKRTGVKFNEIIDLTLKGDHKTLRQKAPLHVVVLDMVVKHLPNPIEAQKYRIPHLWQGDINSDVGQAMLNCDPKGKMVMVVTKIIIDKHAGEVATGRVWSGTVKSGQEVYLINTKRKARIQQVGIYMGPERINMEAVPAGNIVAVTGLRDAMAGETVAEEPIEPFEALHYVSEPVVTVAIEAKNVKDLPRLIEALRQLAKEDPTLHVKIDEETGQHLLSGMGELHLEVKLYKLKKDWGIDIDVSEPIVVYRESITKPSPMVEGKSPNRHNRFYIVVEPMPDEIYNAIKEGIIPEGRIKNPKEVAKKLAELGMDYEIARGIVDVYNGNMFLDNTKGVQYLNEVMDLLIDGFHQAMDEGPLAKEPVMKVIVRLIDAQVHEDNVHRGPAQIYPAIRTAIHCAMMKSNPVLYEPYQKVIINIPYEYMGAVSREITQRRGQLVDMKQEGEVMTIIAEAPVAEMFGFAGAIRSATSGRALWSTEHAGFKRVPNELAQQIIRQIRQRKGLDPNPPTEKDVCPLF
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJDP_ECO57
Sequence: MKRHSTLFLFTLLTLTTVPAQADIIDDTIGNIQQAINDASNPDRGRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDDRQHQLNQERRQLEDEERRMEDEYGQ
What are the official names of this protein?
Uncharacterized protein YjdP.
Protein: CI043_HUMAN
Sequence: MDLPDESQWDETTCGLAVCQHPQCWATIRRIERGHPRILGSSCKTPLDAEDKLPVLTVVDILDSGFAAHHLPECTFTKAHSLLSQSSKFYSKFHGRPPKGLPDKSLINCTNRLPKFPVLNLNETQLPCPEDVRNMVVLWIPEETEIHVSQHGKKKRKNSAVKSKSFLGLSGNQSAGTRVGTPGMIVPPPTPVQLSEQFSSDFLPLWAQSEALPQDLLKELLPGGKQTMLCPEMKIKLAMMKKNLPLEKNRPDSVISSKMFLSIHRLTLERPALRYPERLKKLHNLKTEGYRKQQQRQQQQQQQQKKVKTPIKKQEAKKKAKSDPGIQSTSHKHPVTTVHDRLYGYRTLPGQNSDMKQQQQMEKGTTSKQDSTERPKMNYYDHADFHHSVKSPELYETEPTNKDISAPVDAVPEAQAARQKKISFNFSEIMASTGWNSELKLLRILQDTDDEDEEDQSSGAE
What are the official names of this protein?
Uncharacterized protein C9orf43.
Protein: PANB_SHEHH
Sequence: MSKITSSTLRTFKQEGKKFTALTAYDASFASAFDSEGIDVLLVGDSMGMVLQGHSDTLPVTVDDIAYHTRCVRRGIEHSLLIADMPFMSYATPEQTMVNATTLMQAGASMVKVEGGHWLLESVAMLTERGIPVCAHLGLTPQSVHVFGGFKVQGRDADNAQRILDEAKALEAAGAQLLVVECIPASLAKAITQALTIPVIGIGAGKDTDGQILVMHDVLGISSGYIPRFSKNYLKQTGEIRAAVRAYIDEVAQGVFPGDEHTFN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_HISS2
Sequence: MVYSYTEKKRIRKSFGKRPQVLNVPYLLTIQLDSFDKFIQRDPDGQQGLEAAFRSIFPIVSNNGNTELQYVSYQLGEPVFDVRECQIRGTTYAASLRVKLRLVSYDKDAASGTIKDIKEQEVYMGEIPLMTSNGTFVINGTERVVVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLYARIDRRRKLPATIILRALNYTTEEILDLFFDKVSFEIKDNKLLMTLVPERLRGETASFDIEANGKVYIERGRRITARHIKALEKDKITQVEVPTEYIVGKVSAKDYVDLTTGEIICPANMEISLELLEKLSQAGYKNIETLFTNDLDFGPYISETLRVDPSYDRLSALVEIYRMMRPGEPPTKEAAEGLFDNLFFSSERYDLSAVGRMKFNRSLGIEDTTGSGTLSKEDIVNVMRKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLESVTPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHATHYGRVCPIETPEGPNIGLINSLSVYARTNDYGFLETPYRKVVNGQVTEEIEYLSAIEEGKYVIAQANSNLDNELRFTDAFVTCRGEHGESGLYRPEEIHYMDVSTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPVALDSGVAVVAKRGGTIQYVDASRIVVKVNEDETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVQLGEPIERGEILADGPSTDLGELALGQNMRVAFMPWNGYNFEDSMLVSERVVQEDRFTTIHIQELSCVARDTKLGSEEITADIPNVGEAALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLVEELEILEAGLFARVRNLLLSGGFNDKQLENLDRTQWLEQTLVDEDKQNQLEQLAEQYEELRKDFEHKLEIKRSKIIQGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVDIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMIKQKQDVEKLRGYIQKAYDLGDGSQKVDLSTFTDEEVLRLAKNLRKGMPLATPVFDGAHEKEIKALLELGGLPTSGQIILFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVGGTHQMDPGTPESFNVIMKEIRSLGINIDLDEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: EIF3B_ASHGO
Sequence: MAAVFDDIRLEDIPVDDVDMQDLEETYAVERSIEFDRYVVVDGAPVAPEAKVGALQKVLTKLFSQAGSVVDMDVPVEEGRTKGHLFIEFEDAGAARRAIKMFNGKKLDVKHRLWVNGLDDMERYGRPDFSTEYREPVVPEFEATEYPRSWLQDETGRDQFVLQKGEMTAVFWNRNNLQPENVVEPRRNWSNSILNFSPHGTYLFSFHDQGIASWGGPQFKRLRRFAHPDVKAISMSSTEKYLVTFSSEPLEVSDEPNEACPFGPESRGHQLCIWDVATGVCVKTFALPPQQQLQWPMVKWSFDDKFCARLGPGAIAVYETEKNFQLLGGKVMKIEDVQDFSFAPKGIKLASNRPNDPPSTVMVYWTPESNNQSCKAVLIELPNRRVLRTINLVQVTDVSFHWQNQAEFLCVQVDRHTKSRKTIFTNMEICSLTAREFPFEKVEIKDRCMRFAWEPNSDRFVIISRSENVNDNPAIAKNVVSFYAPEKKVDKKGVIIDKELSIFKKWKLVRAIDGKFSNEITWSPAGRFVCVAAIGKIGSRNENIDFYDMDYPNTEKIINTATDVNATLRDVAHINYASATDYEWDPSGRYLAFWSSAWKHKAENGYKVFNLAGAIVREELITDFNNFFWRPRPDSLLSNSEKKKVRKNLKEWSAHFEEQDAMEADSATRELILKRRNWLDEWSKYREACKQTLSESGLSICDCVELSTKDEDCELVEEIRETVVEESTEEVPFFEE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3 p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAS10_MOUSE
Sequence: MVKKSRRRGAAQWAAVRAQAGLTATDENEDDLGLPPSPGDSSYYQDQVDEFHEARSRAVLAKGWNEVESGEEDGDEEEEVLPLDIDDGDDEDGESSEEEEVGEDDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEVEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLKKESPELLELIEDLQAKLTEVKDELEPLLQLVEKGVIPTGRGSEYLKTKYNLYLNYCANISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTAKDGAVKKEMTPKAKLTKTKPKSVKQAAAVALTDEPDFDGAALKYYKEMEDRQELKRKKEENSAEEQALEEQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRKAKIRRRGQVREVRREEQRYSGELSGIRAGVKKSIKLK
What is the function of this protein?
Essential for gene silencing: has a role in the structure of silenced chromatin.  Plays a role in the developing brain.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
Something about silencing protein 10, Charged amino acid-rich leucine zipper 1, Crl-1, Disrupter of silencing SAS10, UTP3 homolog.
What is the protein family that this protein belongs to?
Belongs to the SAS10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAX_I34A1
Sequence: MEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREEKRQLKKGLKSQEQCASLPTKVSRRTSPALKILEPMWMDSNRTATLRASCLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: DUSA_VIBVU
Sequence: MTHSCRLSVAPMLDWTDRHCRYFHRLMTKETLLYTEMITTGAIIHGKGDFLAYNQEEHPVALQLGGSNPQDLATCAKLAAERGYDEVNLNVGCPSDRVQNGRFGACLMAEPQLVADCVAAMKEVVDIPVTVKTRIGIDDQDSYEFLTDFVSIVSEKGGCEQFTIHARKAWLSGLSPKENREIPPLDYPRAYQLKKDFSHLTIAINGGVKSLEEAKEHLQHLDGVMIGREAYQSPYLLASVDQELFGSQSPIKKRRQIVEEMYPYIEQQLANGAYLGHMTRHMLGLFQNMPGARQWRRHISENAHKPGSGIEVLQQALAKIPQELDV
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U20 and U20a in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(20/20a) synthase, U20-specific dihydrouridine synthase, U20-specific Dus, tRNA-dihydrouridine synthase A.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusA subfamily.
Protein: RIMO_CUTAK
Sequence: MSAADHLMTVHLVSMGCARNDVDSEELAARMEAGGFRLVDDPAEAETVVVNTCGFIEQAKKDSVDTLLAAADLKGNGITTSVVAVGCMAERYGRELAESLPEADAVLGFDDYGDIAGRLRTILDGGSLETHVPRDRRTLLPISPVDRPTARAEVSVPGHGTAPDLSASVTPDSGPRATRRRLGTGPSAPLKMASGCDRRCAFCAIPRFRGSYLSRPIAEIVEEARWLVDHGVKEVFLVSENSSSYGKDLGDLRLLEKLLVNLDQVDGLEWIRVSYLQPAELRPGLIDTILATDKVVPYFDLSFQHASGPLLRRMRRFGDAESFLNIIDSIRSRCPEAGLRSNFITGFPGETDADVAVLADFLQRARLDVAGVFAYSDEEGTEAAGLDGHVDEDVVTARREDLADLTDELVSQRAEDRIGTRGRVMVEEIDEAVIGRAEHQGPEVDGCVTLVDAAAVSVGDIVDVEFVGSDGVDLVARPANA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAST_XENLA
Sequence: MNSPGGRNDKKKPVTPAAETGPGSPTTPPSTETQVVLAPPSPHKRNLHLFSYPLLAVFSLLRFLAFQLGLLFVWCCELLSRSVMADKGRTVASTAAAQDRPQEPEVVRSYHQQAFQYISLALRVDEEEKDQKEQAVQWYKKGIEELEKGIAVPISGKGEQYDRARRLQAKMSTNLIMAKDRLQLLAKLQADIQGPHSQMEVCSDNTNLPCRNGLLKPEKGAVPKKKDPPPITSNSYSRTKAPPKSGSLGNRIPNCTSVPTSARQAGAHTPSNRGATGKNNTRTNKPATPTTAVRKKDMKNLRNVDSNLANLILNEIVDSGPSVKFADIAGQDLAKQALQEIVILPSIRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFSVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSGGDDRVLVMGATNRPQELDDAVLRRFTKRVYVALPNEETRLVLLKNLLSKQGNPLSEKELTQLSRLTEGYSGSDITALAKDAALGPIRELKPEQVKNMAASEMRNMKYSDFLGSLKKIKCSVSHSTLESYIRWNQDFGDTTV
What is the function of this protein?
ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated.  Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold.  Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.  Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis.  Also plays a role in axon growth and the formation of axonal branches.
What are the official names of this protein?
Spastin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Spastin subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Nucleus. Note=Forms an intramembrane hairpin-like structure in the membrane.
Protein: CYSN_ECODH
Sequence: MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: 2AAG_ARATH
Sequence: MSMVDEPLYPIAVLIDELKNDDIQRRLNSIKRLSIIARALGEERTRKELIPFLSENNDDDDEVLLAMAEELGGFILYVGGVEYAYVLLPPLETLSTVEETCVREKAVDSLCRIGAQMRESDLVEHFTPLAKRLSAGEWFTARVSACGIFHIAYPSAPDVLKTELRSIYGQLCQDDMPMVRRAAATNLGKFAATIESAHLKTDIMSMFEDLTQDDQDSVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTDLVPAYARLLCDNEAEVRIAAAGKVTKFCRILNPELAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDEKLGALCMQWLQDKVHSIREAAANNLKRLAEEFGPEWAMQHIVPQVLEMINNPHYLYRMTILRAVSLLAPVMGSEITCSKLLPAVITASKDRVPNIKFNVAKMMQSLIPIVDQAVVENMIRPCLVELSEDPDVDVRYFANQALQSIDNVMMSS
What is the function of this protein?
The A subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.  Involved during developmental process such as seedling and floral developments.  Seems to act as a negative regulator of PP2A catalytic activity.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A gamma isoform, AtA gamma, PP2A, subunit A, gamma isoform.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit A family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: ENASE_MOUSE
Sequence: METSSVLTRGAARQRSPAAPEKQARDQTERRPGRRRQGRRINEDQEEEAVFREVVSFTPDPLPARYYDKDTTRPISFYLSTLEELLAWTPLMEDGFNVALEPLVCRRPPLSSPRPRTLLCHDMMGGYLEDRFIQGSEVQNPYSFYHWQYIDIFVYFSHHTVTIPPVCWTNAAHRHGVCVLGTFITEWQEGGRLCEAFLAGDEPSFQAVADRLVQIAQFFRFDGWLINIENSLTPAAVRNTPLFLQYLTAQLHQQVPGGLVLWYDSVVQSGQLKWQDELNDQNRVFFDSCDGFFTNYNWREDHLQRMVAQAGERLADVYVGVDVFARSNVVGGRFDTDKSLELIRKHGFSAALFAPGWVYECLEKSDFFQNQDKFWSLLERFLPTHSICSLPFVTSFCLGLGTRRVCYGKEQAVGPWYHPSAQETQPLFGEHKLAGDSRGWVKTHCCLTDAWHGGSSLLLRGLIPPEVDSVAVRLFSLHIPVPPKVFLSMVYKFEGSTDVQVALELTTGDASSCHVGGMLVLNETGSRHSPRPLRVPPTRLARWASSCGQQLSGGWIQRCYEVNLRGCLLQDLLVSFSRPPGSREEESFICRLGEIQVVDASSLLAPLPRVQNVTISQIRWLPLITGSEGLPTRLLLSCTLHWSYLLLRARCFRIHCWKRTGSSSSVAESPETEKPTFLGLAFANQYRVVDLAVEAAGFGQDGRVEFLVEPVPREGFLVPQAEWGKAVLLFSVPQ
What is the function of this protein?
Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core.  Involved in the processing of free oligosaccharides in the cytosol (By similarity).
What are the official names of this protein?
Cytosolic endo-beta-N-acetylglucosaminidase, ENGase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 85 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.