PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_FRATW
Sequence: MSKHKVSPATIAKNKKALHDYTILEKFEAGIVLQGWEVKSIRAGKVQMVDSHVHIKHGEAWLFNCLITPLLSASTHVVADAAATRKLLLNRREINKIMGRIEQKGFTCIPLSMYWKGPRVKVEIALAQGKKVHDKRQAQKDKDWAREKDRLFKKAYK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PSBZ_NOSS1
Sequence: MTIIFQFALVALVLVSFVLVVGVPVAYATPQNWVESKKLLWLGSGVWIALVLLVGLLNFFVV
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: SPTP_SALPA
Sequence: MLRYEERKLNNLTLSSFSKSGVSSDTRLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQNQKILQTFLQALTEKYGEKAVNNALYMSSINMNKPLTQRLVVQITECVKGADGGFINIIKNKDNVGVMNAALVIKGGDTKVTEQNNDVGAESKQPLLDIALKGLKRTIPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQSLNKIPEAKQLNDYVTTLKNIQIGADRFSQWGTCGGEVERWIDKASTHELTQAVKKIHVIAKELKNVTAEFEKIKAGASMPQTMNGPTLGLARFAVSSIPINQQTQVKLSDGMPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKECSCLAVLTSEDQMQAKQLPAYFRGSYTFGEVHTNSQKVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIHCLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRNSRNNRMLEDASQFVQLKAMQAQLLMTTAS
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities.  After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE.  This function is independent of its tyrosine phosphatase activity, which remains unclear (By similarity).
What are the official names of this protein?
Secreted effector protein SptP.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the YopE family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cytoplasm.
Protein: CB222_PEA
Sequence: LAVPGILVPEALGLGNXV
What is the function of this protein?
May channel protons produced in the catalytic Mn center of water oxidation into the thylakoid lumen.
What are the official names of this protein?
Chlorophyll a-b binding protein 22, chloroplastic, LHCII type I CAB-22.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RRF_CHLMU
Sequence: MTLTSAEKEMSGVLTFFQKEIRGFRTGKAHPALVETVTVEVYGTTMRLSDIASISVSDTRQLLISPYDAGNVSAISKGILAANLNLQPIVEGATVRINVPEPTEEYRREVIKQLKRKSEEAKVSIRNIRRTCNDRLKKDDSLTEDAVKGLEKKIQELTDKFCKQIEELAKQKEAELSSI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPY1R_CAVPO
Sequence: MNSTSFSQLENHSVHYNLSEEKPSFFAFENDDCHLPLAVIFTLALAYGAVIILGVSGNLALILIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWIFGEIMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYIGIAVIWVLAVASSLPFMIYQVLTDEPFQNVTLDAFKDKLVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDSKYRSSESKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPLAFKKISCVENEKI
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.
What are the official names of this protein?
Neuropeptide Y receptor type 1, NPY1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HOXM_CUPNH
Sequence: MVVAMGIGNVLWADEGFGVRCIETLQQRYQFAPQVCLVDGGTQGLYLIHHVQAASRLLIFDAIDYGLPPGTLRIIEDEAVPKFLGAKKMSLHQTGFQEVLLLAQLTGQYPQQVVLIGCQPEELEDYGGSLRRVMKAAVEDAVEKGADLLRRWGGMPVPRTAELAPAEAVTVPHLALDRYEAERPSPRAACRIGDERFMPQDL
What is the function of this protein?
Absolutely required for hydrogenase activity.  Mediates the attachment of hydrogenase to the bacterial membrane; attachment is a requirement for enzymatic activity.
What are the official names of this protein?
Hydrogenase expression/formation protein HoxM.
What is the protein family that this protein belongs to?
Belongs to the peptidase A31 family.
Protein: HSLV_ACTP2
Sequence: MTTIVCVRKDGKVAIGGDGQATLGNCVEKGTVRKVRRMYKDKVVTGFAGSTADAFILRDLFEKKLELHQGHLIKSAVELAKEWRTERSLRKLEAMMIVANESEFLLVSGSGDVIEPEQDVLAIGSGGNYAKAAALALLRTENNLSAKEIVAEALKIAGDIDIYSNHNHVIEEV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_RHOP2
Sequence: MSKSASRARLADIIRTRSFGRGEITLASGRKSDFYFNLKPTMLDPEGAALLAELTYEALRDEQVDYIGGLEMGAVPLAGAIAQLSWLKNHPIAAFFVRKKPKEHGARLAVEGLAKGESLAGKRCVIVEDVTTTGGSAIKAVEAVRESGAEIVLVLTMVDREEGATEAFAAAGLPFRSLYKASEFLNR
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CYC4_STUST
Sequence: MNKVLVSLLLTLGITGMAHAAGDAEAGQGKVAVCGACHGVDGNSPAPNFPKLAGQGERYLLKQLQDIKAGSTPGAPEGVGRKVLEMTGMLDPLSDQDLEDIAAYFSSQKGSVGYADPALAKQGEKLFRGGKLDQGMPACTGCHAPNGVGNDLAGFPKLGGQHAAYTAKQLTDFREGNRTNDGDTMIMRGVAAKLSNKDIEALSSYIQGLH
What is the function of this protein?
Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems.
What are the official names of this protein?
Cytochrome c4.
Protein: LGT_SHIB3
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DISA_CLOTE
Sequence: MIKVRLQKDNDLMDILNIMAPGTPLRDGLENILRAKTGGLIVIGDSEEILDIVDGGFTIDAEYSPSYVYELAKMDGAIILSGDVKRIIRANAQLMPDPSVPTFETGTRHRTADRIAKQTGNIVIAISQRRNIITIYRNNIKYVLRDSSVILGKANQALQTLEKYVSVLDKVINNLNVLEFRDLVTLFDVMTAIQRTEMVMRIVWEMERYICELGNEARLISMQLNELVRYVEEDEILLIRDYCETYMDYTEVYDEIQSMSSEELINLDQISKILGYTGVPLVDTFISPRGYRMLHRIPRIPSNVIENVVKNFKELKAVMEASYEQLDKVEGIGEARAKAIKNGLRRLKEQANIDKNIVTR
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: ACCA_YERPP
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGAWQIAQLARHPRRPYTLDYIANIFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVLNDEELLNRRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_RHIEC
Sequence: MAVISKKIPAPDKVEIKTALLSVFDKTGIVELAQALSERGVRLLSTGGTYKAIAAAGLAVTDVSDITGFPEIMDGRVKTLHPTVHGGLLAIRDDNEHQEAMKKHGIEGIDLAVINLYPFEEVRAAGGDYPTTVENIDIGGPAMIRASAKNHAYVTILTDPNDYAEFKEQLSADAGKTAYAFRQRMAAKAYARTAAYDAAISNWFAEALSIDTPRHRVIGGVLKEEMRYGENPHQRAAFYVTGEKRPGVSTAVLLQGKQLSYNNINDTDAAYELVAEFLPERAPACAIIKHANPCGVATGSSLIEAYQRALACDSVSAFGGIIALNQILDAETAEEIVKLFTEVIIAPDVTEEAKAIVARKPNLRLLSAGGLPDPRVAGLTAKTVSGGLLVQSRDNGMVEDLELKVVTRRAPTGQELEDMKFAFKVGKHVKSNAVVYAKDGQTAGIGAGQMSRVDSARIAALKAEEAAKALGLAVPMTKGSAVASEAFLPFADGLLSMIAAGATAVIQPGGSMRDQEVIDAANEHGIAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: GCS23_FRAAA
Sequence: MSDARNVAVGVEEEFHILDLTTRQLVPRAEEILQRLDKDSFSPELLKSVVETNSQPTVDLLALRSNLLDLRRRLAEAAGELGLGPAASGTVPILDMDLLDVSRDARYEQMTEDYQIVAREQLICGAQVHVDVADRDLAMAVVAWTAPWLPMLLALSASSPYWLGADSGYASMRTLVWQRWPTAGVAGSFQTAAEYDQLIADLIKSGVISDPGMVYFDVRPSAHLPTVELRICDACPDVDNVILIAGLFRALVGRAIEEIEAGGQAPPPRAELLRAATWRAARSGLEGDLVDIFGAGPVPARAMLRRMLEEVRPQLERYDDWELIDNLAEQAAGRGSSALRQRRAFARRGLLTDVADLILAETRDVPPAGASLGVAPAVSAPDQIAPILLERYQPAGYDEVVDEHGAVRPQYRAVMRTLERLGPDTLDERVGAREAEQTDRGITFRVNGDSASRPFPFDIVPRIVAADDWAVLGRGLGQRVRALEAFLHDVYGERAAVADGIVPPWVVNDAPGLRHGGRAPGRDAIRITTAGIDLVRGGDGGWLVLEDNLRVPSGIAYAVEGRRLAESVLPELGPPPGILRLGTVPALLHDALVAAAPPAVTGEPAVAVLTSGPADSAYFEHAMLAEEMGVPLVEPGALLVDDDVAYRVDDGRRRRVDVLYRRIDEDELFAAPGADGAPLGPALLRAVRAGQVSVANAPGNGIGDDKVVYAYVPRMVTYYLGEQPVLDDVPTYVCGDPEQCEHVLANLDQLVVKPVDGFGGSGVVIGPHAEPYQLTAVREQILADPRRWIGQEVVALSTHPTWHDSHLEPCAVDLRVFVYAGVEPVVVPAALSRVAPPGSLIVNSSQGGGSKDTWIPRR
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-3, Gamma-glutamylcysteine synthetase 2-3, GCS 2-3, Gamma-GCS 2-3.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: ADT2_YEAST
Sequence: MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (PubMed:24474793).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 2, ADP/ATP translocase 2, Adenine nucleotide translocator 2, ANT 2, Petite colonies protein 9.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LPXA_PARDP
Sequence: MAETRIHPSAVVDPAAQVGEGCEIGPFCVIGPEVGLGRGVVLKSHVVVAGETLIGDETVVFPFASLGEVPQDLKFRGERTRLEIGARNRIREYVTMNPGTEGGGGVTRIGDDGLFMAGSHVAHDCQIGNRVILVNNASVAGHCVLEDDVIVGGLSGVHQFVRIGRGAMIGAVTMVTADVIPFGLVQGPRGHLDGLNLVGLKRRGASREEIHALRDMLAQLGQGSFRDTARHLAEAENGPMVREVLDFILGPSDRSFLAPHP
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_ACTPJ
Sequence: MAKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVSAVNNEIAQAILGKDGSAQTEIDQIMIDLDGTDNKSKFGANAILAVSLATAKAAAASKGLPLYAYIAELNGTPGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGASTLKEALRIGAEVFHNLAKVLKSKGLNTAVGDEGGFAPNLASNADALACIKEAVEKAGYVLGKDVTLAMDCASSEFYNKENGLYEMKGEGKSFTSQEFTHYLEGLCNEYPIKSIEDGQDESDWEGFAYQTKVLGGKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALAAAGTPAPFNGLKEVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: VP5_RRSVT
Sequence: MDKFAEIRKRLKQKHNEWLQQTAAERIEQDAGIKMTARTIQGLRITRNSKNDESSLHVDSATDLEMDVTGASKFESKKETFDYRPNTSSSRIVLTPKSNDCKTEKKLVSGDDVTEISRPTSSSAVEISELPEVCVKVVFSQPCDVSRYPSDATKVRITKCDHANWRGWRSFLHALGICNREIQDSFLEQAASGCSAHVKDVVTAFDRGENLELLCAMAGVNVCLVNVSDEEIELIKISPEPLTCVVRIDFVGSEIKCLPCHATDAALASLFKTALRVYDYGRRIPWMHLSETVTFLSLDKTRTRVNVSNLCFDDGWRNIFEALNNDYPELYLVPENGDPEARSRCFIDPERQIEEEERYRAAKEAYLKRMNTPLEWWQEEVLTLTDGEREPKLDEFFFRTLLPRIIRQNAHCGDNPTEKLPMIGFGFDAIMKSRAERASQMSIGAKGNAGKEVGLPLRYKQHVINFRKREMHQKNSNIMTGYLPGGLLHDTLGGIVICLRLDIFEDTVISVYGIYNGMKLIRLICMICVYSGINIPGRPYFVYEVGEGILLTPGMFEEYFTGARTVSRLTSTHGVIHLGKLERCVRQFNNYLSAFKIKPGEIIDRSRAPRCKAKEKKFVPRSVGKGVFYASDLANYPFEINRHDKRSGLFHVGEIDFQAAISSIWPQMMCHYMASEDREDKQDDEKSKSDNFLVPEAVDPSLVIPSAAIYDCGMSKVNPENAKVKTRGNKLLLPCGMLEHCRATSLTKHRCLLPYLGVLACDLPYGSERMPACLGCGRLYPQQILAKLCAQVRCPAWPSTSDCLIRSE
What are the official names of this protein?
Putative minor structural protein VP5.
What are the subcellular locations of this protein?
Virion.
Protein: B2H_SICPE
Sequence: WIMGHMVNSIEQVDKFLDLGANAIEFDVDFDDDGVAKYTHHGIPCDCGRLCNKYAVFTEYLDYVRQVTTPGDPKFRKELVLLALDLKLQRISSEKAYAAGVDVATKLLDHYWMRGKNGGRAYILLNIPLVKHYEFIRAFKDTLRKEGHEQYNAKVGINFTGNEDLDEIRKVLEKLGEDEHIWQADGIASCIPRGTERLKKVLEKRDTPGYKYISKVYAWTLVRSSIMRRSLSLGVDGVMSNYPDIVVKVLKEKKFSDKFRLATYADNPWEKFTPI
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SpeSicTox-betaIIA1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSTR_VIBCH
Sequence: MKIKERLANQRKAINKTQAQMADEIGISLTSYKKYESGEGLPTMENLVKIADALEISIDELCGRWATDENQELMLRLKKIQQLDEEEQKAISMVLESMLIRHSTKSILNHGA
What is the function of this protein?
Transcriptional repressor of the integrated CTXPhi phage gene rstA2.
What are the official names of this protein?
Cryptic phage CTXphi transcriptional repressor RstR.
Protein: VIF_HV1LW
Sequence: MENRWQVMIVWQVDRMRIRTWKSLVKHHMYVSGKARGWFYRHHYESPHPRISSEVHIPLGDARLVITTYWGLHTGERDWHLGQGVSIEWRKKRYSTQVDPELADQLIHLYYFDCFSDSAIRKALLGHIVSPR
What is the function of this protein?
Counteracts the innate antiviral activity of human APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells (By similarity).
What are the official names of this protein?
Truncated virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion (By similarity).
Protein: RR19_NEPOL
Sequence: MPRSLKKGPFVANHLLRKIEKMNGKGEKHVITTWSRASTIIPIMIGHTIAIHNGKSHLPIFINDRMIGHKLGEFVLTRNYRGHGKTDKKARR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NANA_STRR6
Sequence: MSYFRNRDIDIERNSMNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASEQPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLENVETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSSATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAELPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTVYNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIPALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASDPSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILYREGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPHKGRILIPVYTTNNVSHLNGSQSSRIIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMNNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQMSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSLQELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGVIGLEFDSEVLVNKAPTLQLANGKTARFMTQYDTKTLLFTVDSEDMGQKVTGLAEGAIESMHNLPVSVAGTKLSNGMNGSEAAVHEVPEYTGPLGTSGEEPAPTVEKPEYTGPLGTSGEEPAPTVEKPEYTGPLGTAGEEAAPTVEKPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ
What are the official names of this protein?
Sialidase A, Neuraminidase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: QHED_COMTE
Sequence: MERLIDNSHGWPGRMVWLLAACLGSAAAFAQTGPAAQAAAAVQRVDGDFIRANAARTPDWPTIGVDYAETRYSRLDQINAANVKDLGLAWSYNLESTRGVEATPVVVDGIMYVSASWSVVHAIDTRTGNRIWTYDPQIDRSTGFKGCCDVVNRGVALWKGKVYVGAWDGRLIALDAATGKEVWHQNTFEGQKGSLTITGAPRVFKGKVIIGKRGAEYGVRGYITAYDAETGERKWRWFSVPGDPSKPFEDESMKRAARTWDPSGKWWEAGGGGTMWDSMTFDAELNTMYVGTGNGSPWSHKVRSPKGGDNLYLASIVALDPDTGKYKWHYQETPGDNWDYTSTQPMILADIKIAGKPRKVILHAPKNGFFFVLDRTNGKFISAKNFVPVNWASGYDKHGKPIGIAAARDGSKPQDAVPGPYGAHNWHPMSFNPQTGLVYLPAQNVPVNLMDDKKWEFNQAGPGKPQSGTGWNTAKFFNAEPPKSKPFGRLLAWDPVAQKAAWSVEHVSPWNGGTLTTAGNVVFQGTADGRLVAYHAATGEKLWEAPTGTGVVAAPSTYMVDGRQYVSVAVGWGGVYGLAARATERQGPGTVYTFVVAGKARMPEFVAQRTGQLLQGVKYDPAKVEAGTMLYVANCVFCHGVPGVDRGGNIPNLGYMDASYIENLPNFVFKGPAMVRGMPDFTGKLSGDDVESLKAFIQGTADAIRPKP
What is the function of this protein?
Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids.  Methanol is not a substrate.
What are the official names of this protein?
Quinohemoprotein alcohol dehydrogenase, QH-ADH, Alcohol dehydrogenase (azurin), PQQ-containing alcohol dehydrogenase, PQQ-dependent ADH, Quinohaemoprotein ethanol dehydrogenase type I, QH-EDHI.
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS20_NITMU
Sequence: MANSAQARKRARQNISHRNRNMSLRSELRTAIKHVRKAIGSADKNTAQAAYQASVATIDSIADKGIIHKNKAARHKSRLSSAIKAMA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS21_NITWN
Sequence: MQVLVRDNNVDQALKALKKKMQREGIFREMKLRGHYEKPSEKKAREKAEAVRRARKLARKKMQREGLLPMKPKPVFGAGPGAGRGGPAAGPRGPR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.