PharMolix/UniProtQA huggingface dataset:
Protein: HGFA_MOUSE
Sequence: MGRQAWISSLCPLPRPCPFLLLLLLLVVPRGAQPQAGRNHTEPPGPNVTATPVTPTIPVISGNVSTSTESAPAAETEGPQSERYPPPSSSSPPGGQVLTESGQPCRFPFRYGGRMLHSCTSEGSAYRKWCATTHNYDRDRAWGYCAEVTLPVEGPAILDPCASGPCLNGGTCSSTHDHGSYHCSCPLAFTGKDCGTEKCFDETRYEYFEVGDHWARVSEGHVEQCGCMEGQARCEDTHHTACLSSPCLNGGTCHLIVGTGTSVCTCPLGYAGRFCNIVPTEHCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAAAVLLGLGPHAYCRNPDKDERPWCYVVKDNALSWEYCRLTACESLARVHSQTPEILAALPESAPAVRPTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGNSFCAGSLVHTCWVVSAAHCFANSPPRDSITVVLGQHFFNRTTDVTQTFGIEKYVPYTLYSVFNPNNHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSSYSNSLLEALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYLYGIISWGDGCGRLNKPGVYTRVANYVDWINDRIRPPKRPVATS
What is the function of this protein?
Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
What are the official names of this protein?
Hepatocyte growth factor activator, HGF activator, HGFA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
Protein: DHPS_STRP1
Sequence: MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQMIADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARAALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRAQAALDAGVPKNNIWVDPGFGFAKSVQQNTELLKGLDRVCQLGYPVLFGISRKRVVDALLGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: ECHD3_HUMAN
Sequence: MAAVAVLRAFGASGPMCLRRGPWAQLPARFCSRDPAGAGRRESEPRPTSARQLDGIRNIVLSNPKKRNALSLAMLKSLQSDILHDADSNDLKVIIISAEGPVFSSGHDLKELTEEQGRDYHAEVFQTCSKVMMHIRNHPVPVIAMVNGLAAAAGCQLVASCDIAVASDKSSFATPGVNVGLFCSTPGVALARAVPRKVALEMLFTGEPISAQEALLHGLLSKVVPEAELQEETMRIARKIASLSRPVVSLGKATFYKQLPQDLGTAYYLTSQAMVDNLALRDGQEGITAFLQKRKPVWSHEPV
What is the function of this protein?
May play a role in fatty acid biosynthesis and insulin sensitivity.
What are the official names of this protein?
Enoyl-CoA hydratase domain-containing protein 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MTNX_BACAH
Sequence: MSIQVFCDFDGTITNNDNIMSIMEKFAPPEAEEVKNRILSQELSIQEGVSQLFQLIPTNLHDEIIQFLIETAEIRNGFHEFIQFVNENNISFYVISGGMDFFVYPLLQGLIPKEQIYCNETDFSNEYITVNWPHPCDRLCQNHCGLCKSSLIRKLSDTNDFHIVIGDSITDLQAAKQADKVFARDFLITKCEENHISYTPFETFHDVQTELKHLLEVKL
What is the function of this protein?
Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase, HK-MTPenyl-1-P phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MtnX family.
Protein: GLOX_VITPS
Sequence: MILDAAIVALADLPGTWELIVPNAGIASMHTAVTRYGTVVLLDRTNIGPSRKMLPKGHCRYDPKDEVLKRDCYAHSVILDLNTNKIRPLKILTDTWCSSGQFLPDGSLLQTGGDLDGVKKIRKFVPCGPHGFCDWEELKDVELETGRWYATNQILPDGSVIIVGGRAANSVEYYPPRKGGAVQLPFLSDVEDKQMDNLYPYVHLLPNGHLFIFANNKAVMYDYTSNKVMLEYPPLDGGPRNYPSAGSSVMLALEGDYSMAIIVVCGGAQFGAFIQKSTDTPAHGSCGRIVATSPHPVWEMEDMPFGRIMGDMVMLPTGDVLIINGAQAGSQGFELASSPCFFPLLYRPNQPLGLRFMTLTPGTVPRMYHSTANLLPDGRVLIAGSNPHYFYKFAAEFPTELRIEAFSPEYLFADKANIRPVIDESPEMVRFGEQFDVFVSVSLPVVGSMEVNLASAPFATHSFSQGQRLVKLTVSPTVPDADERYRIVCTAPPGGKIAPPGYYMMFAVNLGVPSVARWVQLVP
What is the function of this protein?
Catalyzes the oxidation of aldehydes to the corresponding carboxylate by coupling the reaction to the reduction of dioxygen to hydrogen peroxide.  Substrates include glyoxal and other aldehydes (By similarity).  Involved in disease resistance against the grapevine powdery mildew E. necator.  Is sufficient to confer disease resistance to E. necator (PubMed:20512385, PubMed:23090239).  Can produce hydrogen peroxide in response to E. necator infection, and this may directly play a role in the defense mechanism during plant-pathogen interactions (PubMed:23090239).
What are the official names of this protein?
Aldehyde oxidase GLOX, Glyoxal oxidase, VpGLOX.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: MUTS_HALWD
Sequence: MTTDTDTDVDAGTDLEPQPEGPPEKMLTRRTELTPMLSQYLDCCEAHPDALVLFQVGDFYEAFCEAATTVAQVCEVTLTQREDSTGTYRMAGVPIDNATSYIEALLSADFRVAIAEQVEEAEATSGLVDRAVTNIITPGTVTNGDLLTDAAATYLGAVSITDSDGDASEMTGAIATVDVSTGACRVTSVEHDQIYEELSRLRPAELLIGPEVDTKTIESSSLPFETMQTTHNSGAFELATATQTLEAYVDEPTAFLSSAERRAVGAVLDYAEYTQGDCGPLEYVSRIRRYKTDTALRVDATAIQSLELFDSRQPYGETLIETIDETSSALGRRTLESWLRRPLADHEAIKTRYDAVAALAENPLVVETLTEKLSHIYDLERLTARTAREQADARDMRSLLQSLDSIPEIKSALIEVLTETELPAETLEQLQAELDSLDDIRTLIDTAVCSDPPQTVTDGDVIAKGFNDDLDDIREREEAGREWVSELETRERERTGIDSLEVGYTEVHGYYIEVTNPNLDHVPDEYTRRQTLKNAERFYTPALKRREDEIIAASNRADKLEYELFCDIRAEVAAETSRLQAVADAIGRLDALVSFATIAISHAYVRPEITADTLAIEAGRHPVVEQTQAEFVPNGITFEKGHIAMITGPNMSGKSTYMRQIAHICILAQAGSFVPADAAQIPVLDRIFTRIGASDDISGGESTFMREMSEMTDILHNATESSLILLDEVGRGTSTTDGRAIARATVEFIHNEIGARTLFTTHYHDLTTVTGSLPSAFNLHFKVHRKTHPDNDASVTFLHRVTSGAADSSYGVEVAKLAGVPTPVVEQAQRYIHTEGEDYTEISEQGTHHHDELTHAEMVSVDHDNQQNQASDDDEIARSPRGADTNTDAGINQSDVSANIDVLKSLRDIDIARMTPLEALNMLENLQRRLDE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DMT1B_XENLA
Sequence: MQNNEETYSKTRSTGQHPSGVHGKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPIAAELLIKREHGGSSSCLMLESSSTQTTSTPTSGSTTSSDGKMLIQDIPSITSRGHMESTSELVMDSPYYSNFYQPPLYPYYNNLYNYPPYQMAMTAESTSGNDMGGISGPPMKSSHRNHPAAYVPSQSGNQWQMKNGDNRFSGHSTSSQFRMHSYYSPYLGQSVPNPACVPSFLTFEEIPSYSEAKASVLSPPSSQDSGIISLCSNSPVSNESTKAVAKQEPNSESSAFTITAAAEDGE
What is the function of this protein?
Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and germ cell proliferation.  Acts both as a transcription repressor and activator (By similarity).
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor 1B, DMRT1-beta.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS11_EHRRW
Sequence: MSVTYNKKKKRNVVVGVVHIHATYNNIIVTITDQQGHSLVSTSAGAYGFKGSKKATPYAAQETAGHAVKTVVEQNGMKTVSIKVSGPGAGREAAIRAVQACNLNVTSIKDTTKLPHNGCKLPGRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PDXJ_PSE14
Sequence: MTQSTRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVLLLKDVLQTRMNFEMGVTEEMLAFAERIRPAHICLVPETRQELTTEGGLDVAGQEARIRSAVERLAKIGCEVSLFIDADERQIAASKRVGAPAIELHTGRYADAQTPTEVAEELQRVADGVAFGLAQGLIVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKALIVAAAR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_STACT
Sequence: MDFINRTTPEIAKDLLGVKLIFDDGENQFSGYIVETEAYLGKIDEAAHSYNGRQTPRVQSMYKDGGTIYAHVMHTHLLINLVTQPAGTAEGVLIRALEPELITDQMIENRNGKVGIDVTNGPGKWTRAFNMSMALDGLRLNEGPLSIDTKARKYPSSILESPRIGVPNKGEWTHKPLRFTVEGNPYVSRMRKSDMLAAEDTWKKHK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RISB_STAAE
Sequence: MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNEDNIDVAFVPGAFEIPLVAKKLASSGNYDAVITLGCVIRGATSHYDYVCNEVAKGVSKVNDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: GLV8_ARATH
Sequence: MKKWSYAKLMTSALLLVFLSIILLAFHGGSRGDNHLYDHVAIGTKDILMGRKLKDLKPKTESLKMINPKKKNGFEYSDQVSSDLSRQEVFVDMMARDYQGPKPRSKPLKNN
What is the function of this protein?
Signaling peptide (root growth factor) that promotes root hairs formation and growth (PubMed:23370719).  Regulates the pattern of root growth and lateral root development by modulating the length and the number of cortical cells in the root apical meristem (RAM), and the anticlinal asymmetric cell divisions in lateral root initiation cells (By similarity).
What are the official names of this protein?
Protein GOLVEN 8, CLAVATA3/ESR (CLE)-related protein CLEL5, CLE-Like protein 5.
What is the protein family that this protein belongs to?
Belongs to the RGF family.
What are the subcellular locations of this protein?
[GLV8p]: Secreted.
Protein: MEND_PARD8
Sequence: MYSDKKNILQLVALLIEHGVSNIVLCPGSRNSPIVHTLANHSFFNCHSVTDERSAGFFAVGLALHGGKPAAVCCTSGTALLNIHPAVAEAFYQKVPLVVISADRPAAWIGQMDGQTLPQPGVFGSLVKKSVQLPEIHTDQDEWYCNRLINEALLELNHHGKGPVHINVPISEPLFQFTTPELPKVRVITRYQGLNVYDRKYDDLIERLNKYSKRMMIAGQMSLIYLFEKKICKLLYKHFTWLSEHIGNRIVPGLPIKNFDAILYATPEEEKEKLVPELVITYGGHIVSKRLKEFLRKHPPKEHWHVSLDGEVADLFGSLTTVIEMDAFEFLEKIAYMLENRQIEYPKAWEYKSRNLPEPEFAYSEMAAIGGLIRSLPAESALHLGNSSTVRYAQLYTVPETVEVCCNRGTSGIEGSLSTAIGYASASQKLNFIVIGDLSFFYDMNALWNGNLHNNLRILLLNNGGGEIFQALPGFKMNERTHRYVTASHQTSAEGWATERGFSYSAVHNAEELAAAMSAFTQTEQPSEHPLFMEVFTDKAEDVRLLKEYYHQLKNSSQAQNI
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: PLD_RICBR
Sequence: MKRKNKKFTEIFIAFILGIAIGVLGYSDYGTDLINQFKISHTPPPKIKHYNISQLSRSKVSTCFTPPSGCTKFIADQIDTARESIYMHAYGMSDSLITAALIDAQARGVQVKILLDRSNLKQKFSKLHELQRAKIEVGIDKVPGIAHNKVIIIDKKKVITGSFNFTAAADKRNAENVIVIEDAELADSYLQNWLSRKARNG
What is the function of this protein?
Could be a virulence factor.
What are the official names of this protein?
Phospholipase D, PLD, Choline phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Secreted.
Protein: YVDQ_BACSU
Sequence: MGILSGNPQDEPMHYGEVFGLWSYVMAGNKMVGNYQMLLNHVGDDDLKKLLRESIEKCQDEIKQVSTILKENGVALPPASPEPPTADLNDIPPGARFLDPDVAASAAAENAAGLVTCSKMMGQSIREDIAMMFGQFHMSKAATGAKYLRLLKNKGWLIPPPLHLQKHHEA
What are the official names of this protein?
Uncharacterized protein YvdQ.
Protein: PYRE_CERS4
Sequence: MIPTSFPPREEIARLTARMLLEIEAVHFRPQEPFTLASGLPSPTYIDCRKLISYPRIRSTLMDFMAVTLLRDAGFEAFDNIAGGETAGIPFAALVAERLGLPMTYVRKKPKGYGRNARIEGVMTEGQRVLLVEDLTTDGGSKLSFVDAIRETGASCAHTAVIFYYGIFPETIGRLQAHGVTLHHLCTWWDVLAEARASGTFDAGTLAEVESFLSNPRDWQDARKPADPTKSL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RSMA_TREPS
Sequence: MCCPNYNSARALAQFLTERGLRMHKKWGQNFLLDPVLRTQLVKILAPERGERVWEIGAGIGAMTALLVQNSDFLTVFEIDRGFVQTLRKLFDAHVRVIEGDVLQQWHAAAAQEQPACVLGNLPYNIAARFIGNTIESGYIFKRMVVTVQKEIGLRMTALPAQKWYSYFSVLCQWQYEVRVIRNVAPVCFWPRPHVVSQALVLTKRNAVPSCVDPALFLHVTKTLFSARRKTVRNNLLTWQKRMPGGAAVCVEELCARAGIDARARAEQLSIYDFITLSDTLRALL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_CLOAB
Sequence: MKVILLKDIKSVGKKGEVINVSDGYARNFLFPRKLAEEANNSNMRVLNLKKDAERKQKLQETEEAQKLANELKGKVLKLSAKAGENGRLFGAITSKDIAAEIKKQFNVDIDKKKVNSETIRKLGNYEIELKLYPEISTKINVLISEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SYDND_CAMJJ
Sequence: MRSHYNTDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPNDSKEAHEIASNARNEFVLIAEGAIRPRGEGLVNPKLKTGEIEVVVSKLTIENESAVPPFTIADESVNEELRLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFLEVETPILTKATPEGARDYLVPSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQPEFTQIDVEMSFCEQKDVINVAETFLKDIFKACGKEIQTPFRQMQYKDAMENYGSDKPDLRFDLKFIDVIDIFAKSNNEIFANIAKDTKKNRIKAIRVPKGDTIFSKRQMQRFEEFVRKFGAQGLAFIQVKEDGLKGPLCKFFSEEDLNELSKRCELEVGDVVFFGAGAKKTVLDYMGRFRIFLANELNLIDPNALEFLWVVDFPMFEQNDDGSYSAMHHPFTMPKNIDETDLEEISSIAYDVVLNGVELGGGSIRIHKNDIQQKVFKLLNIDEEQQKEKFGFLLDALSFGAPPHGGIAIGLDRLIMLVTGANSIREVIAFPKTQRAQCLMTDAPSPASNEAMRELGIKLRENIK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_ENT38
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENATPKAE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: SAC4_ARATH
Sequence: MTSSPSVENGGSGSSGSSALLGCMQQFKLFETQANFYMIGWNGSGVYRILKIDRLEASELNLREDSTAYTKKECYELLKRIHEGNKATGGLKLVTVCYGIIGFIKFLGPYYMLLITERREIGEICGHIVYEVSKSDMIALQHSSVLCNTANLRDENRYKRLLCMVDLTKDFFFSYSYNIMRSFQKNICDHESGGTLYKKMFVWNEFLTRGTRHHLRNTLWTVALVYGFFKQTILSEAGRNFKLTLIARRSRHNAGTRYLKRGINESGNVANDVETEQIVSEDVPVDRPMQISSVVQNRGSIPLFWSQETSRMKVKPDIVLSKRDLNYEATRVHFENLVERYGVPIIILNLIKTNERKPRESILRAEFANAIDFINKDLPEENRLRFLHWDLHKHFHSKTENVLALLGKVAACALMLTGFFYYQLTPAMKLEGYMSLSSSDADTSPHNSSDDDSRDYDSLEKNCRPSKNVANGDYDVKPSRLQSGVLRTNCIDCLDRTNVAQYAYGWAALGQQLHALGIRDAPTIELDDPLSSTLMGLYERMGDTLAYQYGGSAAHNKVFSERRGQWRAATQSQEFLRTLQRYYNNAYMDADKQDAINIFLGTFRPEQGSQAVWELRSDSHSNGRSGEISMGEDEKFLVKRCLSDGNILHESHTPMSAMSRKNESISHRGFVSSHQVTRTHIISESSPDMPAAGDVTLSRCTPSMPSTHFFGDVQKVQHNGSSSIYLSEQEDMSSVSNFVDIEWLSSSENLCENDHLSRPSALTIYSTAETSSSENIITEVKQLTPAMRESGSSSRKGKEPVETELSVHTKIRDDFPDSFKQWVAYGEALCH
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
What are the official names of this protein?
Phosphoinositide phosphatase SAC4, AtSAC4, Phosphatidylinositol 3,5-bisphosphate 5-phosphatase SAC4, Protein SUPPRESSOR OF ACTIN 4, SAC domain protein 4.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: ATI2_ARATH
Sequence: MADKDEAATRGNDWEVVSLTASAYAAAPGPKPVVDSKDDDHKEVTPCYEAETSHPLYMSRHFVFPPTGQLENTSDLTEASLTGSHCKEGSDLSLKGLDLSDDFGGLEFSEDKGKKEENIYTTAMSSLDDERAIGGSHVYEPVEEPTEPVSPSDVTLDLNPIKDDEVANSPPSEEAWWKRSVASLIAQAKETNTVWSICIAAAVMGIVILGQHWQQERWQILQQKWESSIGNEKAGRLMGPISRLKQAFVGGQRRDSFIRASAQNDR
What is the function of this protein?
May be involved in salt stress-induced vesicle-to-vacuole trafficking pathway.  Through its interaction with ATG8F, may enable delivery of the vesicle bodies to the vacuole by an autophagic pathway (Probable).  Plays a role in seed germination in response to exogenous abscisic acid (ABA) treatment (PubMed:22253227).
What are the official names of this protein?
ATG8-interacting protein 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Membrane; Single-pass membrane protein. Note=Under favorable growth conditions, partially associated with the endoplasmic reticulum (ER) membrane network. Upon exposure to carbon starvation, mainly associated with newly identified spherical compartments that dynamically move along the ER network and reach the lytic vacuole.
Protein: RL25_STAAB
Sequence: MASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIENDSAESVVTVVAPTEEPTEEEIEAMEGEQQTEEPEVVGESKEDEEKTEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: DHQSH_PERMH
Sequence: MKEFIVNAINYDKKIVTTAIESGADYIIIPEDKEEEAKKLGRVNFIIADKKGNLTDDFVIVTIKNKQDEEKAAQLAKAGKKVIVRTTDWTIIPLENLIAQSENIYAEVKNADEASIAVGILEKGVKGVVLETEDLNEIKRVASVIKETTEKVELIRAKVTAIIPVGMGDRVAVDTTSLFKRGEGMLVGNSSAGMILVHAETEESPYVASRPFRVNAGAVHMYTRVPGGKTVYLCELEAGKEVMAYDIDGNGRAVVVGRAKIERRPMLLIEAEYNGKKLSAVLQNAETIRVVGGDGSLISVVDLKEGDEILGYVEEAGRHFGMKVEETILEK
What are the official names of this protein?
3-dehydroquinate synthase homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: Y1985_MYCSS
Sequence: MPSVSVWVRSLAPMTTWTRAAIGALGEDLAVKHLDSLGMRVLERNWRCRYGELDVIAEDPAARAVVFVEVKTRTTDHFGGVAEAVTPQKVRRLRRLAGLWLAGRDERWAAVRIDVIGVRIGRQATPEITHLTGVA
What are the official names of this protein?
UPF0102 protein Mmcs_1985.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: TYW2_RAT
Sequence: MERECEKSVVVAVVTEPRFTQRYRDYLEKQKLLDRQYRVEKLRDGTVALPVLAETLSEHHLQELKNRVAPGSTCKLTQLLDPLPSKKARVCSPAQRLCLEVRRWVEDRGVTWSTELEADLPRSWQRHGDLMLLSEDCFQATQWKRLEPELWETVASALGVQRLAKRGRVLPDGTRTPTVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRKNLEINGVADRCQIHFGDNRKLKLSNTADRVNLGLIPSSEEGWPIACQVLRKDVGGILHIHQNVESFSGKNPQPPGSSNMEKKHWPHPQKITTDKQGNRTTGSCMGEMSSASKPEWQRWAESAESQIASLLHQVHGKPWRTRILHVHPVKSYAPHVDHIVLDLECRPCPLVG
What is the function of this protein?
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86 (By similarity).
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 2 homolog, tRNA-yW-synthesizing protein 2, tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
Protein: LUXS_STAAB
Sequence: MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIYKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: PURA_RHOP2
Sequence: MANVVVVGAQWGDEGKGKIVDWLSEQADIVARFQGGHNAGHTLVINGETYKLALLPSGVLRPSKLAVIGNGVVFDPQAFLDEVERLTKQGVAISPENLRVAENVTLILPLHRELDALRENASKATAIGTTQRGIGPAYEDKVGRRAIRLMDLADIDTLPHKIERLLTHHNALRRGLGLAEFEAGAILKELTALAPKLLPYAETVWRLLDIKRREGKRILFEGAQGALLDVDHGTYPYVTSSNTVAAQAATGTGMGPGSVGYVLGICKAYTTRVGQGPFPTELDNEIGRKIGERGREFGTNTGRPRRCGWFDAVLVRQTVRTCGIHGLALTKLDILDGFEQIEVCVGYRLDGKEIDHLPAGEGAQARVEPIYETIEGWKEPTANARSWAELPAQAIKYVRRIEELVGCPVALLSTSPEREDTILVQNPFEA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AC81_NPVAC
Sequence: MTTTERPPPPPLSMSKKETPTLLDSISKKISTTETLQRLRNKNLTTLNKIKYDSELLLHYLYDDHHNKNSDYANNNINVIKISKVKVKKTGASILAHYFAQIHVSTGYSFEFHPGSQPRTFQTIHTDGLIIKVLILCDECCKKELRDYIKGENSFNVAFRNCESILCRRVSFQTVLLTCAILLLLFNVEKFSMINLLIILLILLSLFCHNNYIISNPYIEFCNHKSTNKKYDR
What is the function of this protein?
Plays an essential role in the assembly of nucleocapsids with envelopes.
What are the official names of this protein?
Protein AC81.
What are the subcellular locations of this protein?
Host nucleus. Host membrane; Multi-pass membrane protein. Virion. Note=Localizes to the occluded virion (ODV) envelope.