PharMolix/UniProtQA huggingface dataset:
Protein: GREA_RHIL3
Sequence: MVEKVPMTPGGFVKLQEELRWRQQEERPRIIEAIAEARAHGDLSENAEYHAAKEAQSHNEGRISELEDLTARAEVIDLTKMSGDKIKFGAKVKLIDEDTEEEKTYQIVGDQEADVKAGRISISSPIARALIGKEVGDSIEVNAPGGSKAYEILQVSWG
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ATPE_BACP2
Sequence: MKTVQVNIVTPDGPVYQADVEMVSVRAESGELGILAGHVPMVAPLKIGAVRLKHSGSTELVAVSGGFVEVRPEQVTILAQAAETSDKVDVDRAKSAKQRAEEHLNHPNESDVRRAELALKRALNRLNVAGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PRNK_THEKO
Sequence: MNKARYTQDVPEDRIKLLESIASYNKPFTLMVVGGVDSGKSTLITFLGNELLSLGFKVAVVDSDVGQKGVLPPGTISLAIPEGPFESMSELEGVAHYFVGTTAPSQFIGEMAVGVKRMVEIARNVADVVLIDTTGFVTGVGAEMKRLKAELVKPDIIAVIHSGELSGLVKALEPYGGVIELAVSETVKRYPLEERRNLRAEKWRNYFRDSQLVEFSASEVAITGTSLFHGIPLNADENELLEKAFGWLVVAGWKNKGYTVVKADVEKFPRAHSRELKAIDFEKLSNLLVGLIDGEGLCMGVGVLKWINFSEGRLQILTPVRDLSGVREIRFGRIRVTEEGEELGLLRRDEL
What is the function of this protein?
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA).  Exhibits a strong preference for ssRNA (By similarity).
What are the official names of this protein?
Polyribonucleotide 5'-hydroxyl-kinase TK1956, Polynucleotide kinase TK1956.
Protein: ATPG_SHEPA
Sequence: MANAKEIKTKIASVQNTQKITSAMEMVAASKMRKAQDRMAASRPYAENMRKVIGHVAQGSLEYKHPYLEVREAKRVGYIVVSTDRGLCGGLNVNLFKKVVADVKKQREAGAEVEFCTIGARSAQFFNSFGGQVSASASGLGDAPKLADLIGTVRVMLEAYNEGKLDRLYVVFNKFVNTMTQAPVIEQLLPLPKSEDDEFTHQWDYIYEPDPKLLLDTLLVRFVESQVYQGVVENIASEQAARMVAMKAATDNAGELIGDLQLVYNKARQAAITQELSEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAW1_HUMAN
Sequence: MKLKSLLLRYYPPGIMLEYEKHGELKTKSIDLLDLGPSTDVSALVEEIQKAEPLLTASRTEQVKLLIQRLQEKLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR
What is the function of this protein?
May play a role in axonemal outer row dynein assembly.
What are the official names of this protein?
Dynein assembly factor with WDR repeat domains 1, Outer row dynein assembly protein 16 homolog, WD repeat-containing protein 69.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR69 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: PGK_BACMK
Sequence: MNKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLIEQGAKVILASHLGRPKGQAVEELRLTPVAARLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFYAGEEKNDAELAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAVSGLLMEKELDVLGKALSNPERPFTAIIGGAKVKDKIGVIRHLLDKVDNLIIGGGLAYTFVKALGHEIGLSLCENDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATTQIVGIDSIPSTWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFAEGTKAVGQALADAEDTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELP6_SCHPO
Sequence: MSSLHEHLRPIPEPFSLTLLLGTRETPVTFLFHYYLYHALKAKESTCFLTFSKTLDEHAISMRKWGMDIKTKKNFFFIDGFSMLFAPISKPSKVQAPETKNHIKSVFAPVIQCVEENDFEFENSTIIIEDIDILQSTHALDSTKIQQAILELRKCFSRVIVNVTLGAPLPQQKSLGSSIGHMATRCISCRPLTSGSARRITGFLRLSRMPNHFRSGICETPEDDDKELLYEVTEAGAKVYSKGQVTLQL
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:22768388).  The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244).
What are the official names of this protein?
Elongator complex protein 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the ELP6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TX3_CERMR
Sequence: GVDKEGCRKLLGGCTIDDDCCPHLGCNKKYWHCGWDGTF
What is the function of this protein?
Inhibits mammalian voltage-gated sodium channel subtypes Nav1. 5/SCN5A and Nav1. 8/SCN10A by shifting the voltage dependence of channel activation to more depolarized potentials and by blocking the inward component of the sodium current.  In vivo, this toxin causes erect, elevated tail, initial partial ataxia, followed by recovery over approximately 1 hour after injection and the progressive development of shaking.  Although paralysis subsides, the body tremors never cease and persist until the end of the experiment.
What are the official names of this protein?
Beta-theraphotoxin-Cm2a, Beta-TRTX-Cm2a, Ceratotoxin-3, CcoTx3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 47 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SUCC_ACISJ
Sequence: MKIHEYQGKEILRSFGVPVPRGIPAFTVQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGVKVAKTIDDVKARASEILGMQLVTHQTGPEGQKVRRLYIEDGADIKNELYVSLVTDRGTQKVALIASSEGGMDIEEVAHSTPEKIITEMIDPLTGITPEQSKKVAAAIGLTGASVDQAVDLFAKLYKCYMDTDASLVEINPLNCDSKGNLMALDAKFNFDANALFRHPEIVALRDLDEEDPAEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATPEKVTEAFKIMLKNPKVKGILVNIFGGIMKCDTIATGVITACKAVNLQVPLVVRMKGTNEELGKKMLAESGLPIISADTMAEAATKIVEAVR
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: HS150_YEAST
Sequence: MQYKKTLVASALAATTLAAYAPSEPWSTLTPTATYSGGVTDYASTFGIAVQPISTTSSASSAATTASSKAKRAASQIGDGQVQAATTTASVSTKSTAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTTSAKTTAAAVSQISDGQIQATTTTLAPKSTAAAVSQIGDGQVQATTTTLAPKSTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQITDGQVQATTKTTQAASQVSDGQVQATTATSASAAATSTDPVDAVSCKTSGTLEMNLKGGILTDGKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITPDGNLAIGDNDVFYQCLSGTFYNLYDEHIGSQCTPVHLEAIDLIDC
What is the function of this protein?
Component of the outer cell wall layer.  Required for stability of the cell wall and for optimal growth.  Required for resistance against several antifungal and cell wall-perturbing agents and for tolerance to heat shock.
What are the official names of this protein?
Cell wall mannoprotein HSP150, 150 kDa heat shock glycoprotein, Covalently-linked cell wall protein 7, Protein with internal repeats 2.
What is the protein family that this protein belongs to?
Belongs to the PIR protein family.
Protein: RNPA_ECOBW
Sequence: MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CIDA_STAAT
Sequence: MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DUS11_MOUSE
Sequence: MNQHYGRHGRGRGRDFAACAPPKKKGRNHIPERWKDYLPVGQRMPGTRFIAFKVPLQKKFEAKLMPEECFSPLDLFNKIQEQNEELGLIIDLTYTQRYYKVEDLPETISYIKIFTVGHQIPDNDTIFQFKCAVKEFLKKNKNNDKLIGVHCTHGLNRTGYLICRYLIDVEGMRPDDAIELFNSCRGHCIERQNYIENLQKRHVRKNRNVSAPRTDGLEDSADPTEQVYTNNKPVKKKPRKNRRGGHLAPSQHFQHQTQSSPYSLRKWSQNQSVYQRGLVPPPGPAGEDYSQRRFFWSARPNKWTAESYQRPFYPYYWEWNL
What is the function of this protein?
Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity.  In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro).  Binds to RNA.  May participate in nuclear mRNA metabolism.
What are the official names of this protein?
RNA/RNP complex-1-interacting phosphatase, Dual specificity protein phosphatase 11, Phosphatase that interacts with RNA/RNP complex 1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: Y1274_NEIMF
Sequence: MNLSNHFLVAMPDMEDAFFSQSVVYICKHDEDGALGIAINKPSPITMDMIFSATGKNIPMRMQHDSVMMGGPVQVERGYVVHTPIGNWQSSIGVSDNIALTSSRDVIENISREGAVDKALISIGYSSWGKGQLERELADNAWLTVPADEHILFDIPYEHRYAAAFAKLGIDPLALFSGAGHA
What are the official names of this protein?
UPF0301 protein NMC1274.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: VIAAT_MOUSE
Sequence: MATLLRSKLTNVATSVSNKSQAKVSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQMDILKSEGEPCGDEGAEAPVEGDIHYQRGGAPLPPSGSKDQAVGAGGEFGGHDKPKITAWEAGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGSIRAVVNLFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED
What is the function of this protein?
Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals (PubMed:9395291, PubMed:26912364, PubMed:27601664, PubMed:16701208).  The transport is equally dependent on the chemical and electrical components of the proton gradient (PubMed:9395291, PubMed:27601664).  May also transport beta-alanine (By similarity).  Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake (PubMed:27601664).
What are the official names of this protein?
Vesicular inhibitory amino acid transporter, Solute carrier family 32 member 1, Vesicular GABA and glycine transporter, Vesicular GABA transporter, mVGAT, mVIAAT.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Presynapse. Note=Presents in glycine-, GABA- or GABA- and glycine-containing boutons.
Protein: VPEB_ARATH
Sequence: MAKSCYFRPALLLLLVLLVHAESRGRFEPKILMPTEEANPADQDEDGVGTRWAVLVAGSSGYGNYRHQADVCHAYQILRKGGLKEENIVVLMYDDIANHPLNPRPGTLINHPDGDDVYAGVPKDYTGSSVTAANFYAVLLGDQKAVKGGSGKVIASKPNDHIFVYYADHGGPGVLGMPNTPHIYAADFIETLKKKHASGTYKEMVIYVEACESGSIFEGIMPKDLNIYVTTASNAQESSYGTYCPGMNPSPPSEYITCLGDLYSVAWMEDSETHNLKKETIKQQYHTVKMRTSNYNTYSGGSHVMEYGNNSIKSEKLYLYQGFDPATVNLPLNELPVKSKIGVVNQRDADLLFLWHMYRTSEDGSRKKDDTLKELTETTRHRKHLDASVELIATILFGPTMNVLNLVREPGLPLVDDWECLKSMVRVFEEHCGSLTQYGMKHMRAFANVCNNGVSKELMEEASTAACGGYSEARYTVHPSILGYSA
What is the function of this protein?
Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms (By similarity).  Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds (PubMed:12417707, PubMed:14688293).
What are the official names of this protein?
Vacuolar-processing enzyme beta-isozyme, Asparaginyl endopeptidase beta-VPE, Beta-VPE.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
Protein: AROA_SHESW
Sequence: MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAQGTTTLTNLLDSDDIRHMLASLKQLGVNYRLSQNNTVCELDGLGGVISSASAQELFLGNAGTAMRPLCAALTLGQGEFTLTGEPRMEERPIGDLVDALRKLGANVVYLKNDGFPPLTINATGLNGGDVEIAGDLSSQFLTALLMVAPLAKGSVNIHVKGELVSKPYIDITIALMAQFGVNVINHDYARFEIVAGQRYISPCKVLVEGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGSPLTAVDLDMNHIPDAAMTIATAALFAKGTTVIRNIYNWRIKETDRLAAMATELRKVGAEVEEGNDYIKITPPAVINTAEIDTYNDHRMAMCFSMLAFADCGITINDPDCTSKTFPDYFKQFASLQG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPF1_DROME
Sequence: MIKIKRKTAPPPVEQDSDSDSSFDEEEPQDLEVQEGPVTDSSDEEAASSSKKTAKQGEASEDLKEEDDDDDEEENDDDDEEEDDDDDDDKKTRIPVLNPLSWMRNKEQRLALYKKMKKEKHKKKMQERRARRKAGVPANPGHTIESLREKDQTEVANLNDSDNEELQKELQLDDFSSYFERSYEPKVLITFADNPVTKTRKFGLELSRIFPNALVKIRNKSSVKKICKSAEREEFTDVVIVNEDRRKPNGLLVIHLPNGPTAHFKLSNVKLTSDIKRDHKEITKHRPEVILNNFTTRLGLTVGRMLGALFHHDPEFRGRRAVTFHNQRDYIFFRHHRYEFTKEGKRVKLRELGPRFTLKLRSLQEGTFDSKTGDYAWIISNKRHAMESRRRFFL
What is the function of this protein?
May be required for ribosome biogenesis.
What are the official names of this protein?
Probable ribosome production factor 1, Ribosome biogenesis protein RPF1.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: E3B14_ADE05
Sequence: MKFTVTFLLIICTLSAFCSPTSKPQRHISCRFTRIWNIPSCYNEKSDLSEAWLYAIISVMVFCSTILALAIYPYLDIGWKRIDAMNHPTFPAPAMLPLQQVVAGGFVPANQPRPTSPTPTEISYFNLTGGDD
What is the function of this protein?
Down-regulates the EGF receptor and prevents cytolysis by TNF.
What are the official names of this protein?
Early E3B 14.6 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3_14 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RS6_ACIF5
Sequence: MRHYEIVFLVHPDQSEQVPQMIERYRGMIESDGGHFHRLEDWGRRQLAYPIKKAHKAHYVLMNIECSSVALAELEDAFRFNDAVLRHLILARDEAVTSPSFLARDETDRRERSEETAEGEGEPDHSANEAVVTA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: DAPEL_STRT1
Sequence: MTLDLIKIRRDLHQIPEIGLEEFKTQAYLLERIAEMTEGKDFVEQRTWRTGILVFLHGSAPEKTIGWRTDIDGLPIVEETGLDFKSIHEGRMHACGHDIHMTTALGLLDQMLQVQPKNNMLFLFQPAEENEAGGMLMYEDGAFGDWLPDEFYGLHVRPDFKVGDIATNTNTLFAGTCEVLVTFKGKGGHAAFPHEANDALVAASYFITQVQTIVSRNVDPIQGGVVTFGSFHAGTTNNVIAETAEVYGTIRTLTQEMSLLIQKRVRQIAEGVAASFGMEVDIMLKQGGYLPVENNPALAKELMAFFDASPAVNLIDCLPAMTGEDFGYLLSKVPGVMFWLGIDTPYALHHPKMSPNEEALAFAVSEIGKFLKYKAED
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: NTRB_PROHU
Sequence: METGNLPDNTLILDSLIHSVLVINQEFIICYANHAALQVLAQSRRKLFETPFTDLFSYHSFDAELMQETLANGQSFTDNEVILVIHNQSHTMSLSAQPISEQHILLELAPMDSQRRLSQEQIQQAQQIAARELVRGLAHEIKNPLGGLRGAAQLLAKSLPDPALTEYTQVIIEQADRLRTLVDRLLGPQHPGKKTHQSIHHVVERVAQLISLECPENVTLLKDYDPSLPELSHYPDQIEQVLLNITRNALQAVEKTGGTIILRTRTAFQITLHGERHRLVARIDVIDTGSGIPPHLQDTLFYPMVSGREDGNGLGLSIARNLVDQHAGKIEFTSWPGNTEFSIYLPIK
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC.  In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC.
What are the official names of this protein?
Sensory histidine kinase/phosphatase NtrB, Nitrogen regulation protein NR(II), Nitrogen regulator II, NRII.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_SHESR
Sequence: MAQTQSPLQWLATTFIRGYQIFISPLLGPRCRFNPTCSHYAIEAIKVHGTAKGCWFALKRILKCHPLHPGGSDPVPPKNDRCNK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDK_DESOH
Sequence: MERTLSIVKPDGVERGLIGEVVRRLEKEGLKIIAMKMIHMTRAQAEGFYAVHRERPFFESLTTFMSSGPVVVMVLEGEDAILRYRTLMGATNYKDAAEGTIRRDFATEIERNVVHGSDAPDTAAFEIGYFFNSFEIMGR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPISS_SANSP
Sequence: MENQKVPISSVPNLKDLDMISRPIANFPPSVWGDRFINYACEDENEQAQKERQVEELKEQVRRELAAAIDKPLQQLNIIDATQRLGIAYHFENEIEESLKHIYLHTYVENTCFEGSDDLCSVALWFRLLRQDGYRVSCDVFKKFRDSEGNFKNSLMEDAKGLLELYEATHLSVNGEEMLDDALEFTKTHLELVVSHLNYPLAEQVRHALYQPQHKGLPRLEAVYFFRIYEAYDSHNEALLKLAKLDFNLLQSLHMKELSHMAKWWKSLDFATKFPFARDRLVEGYFWILGVYFEPQYSLARKIIIKVFTMISTIDDIYDAYGTLDELKLFTKAIQRWDIGSLDQLPEYMKPCYKSVLDVYNEIEEEMDNQGSLFRMHYAKEEMKKIVEGYMDEAKWCHEKYVPTFQEYMSVALVTAGYTFLTTISYLGMGEIASKEAFDWLFSHPPIIEASESVGRLMDDMRSHEFEQERGHVASGIECYMKQYGVTEEEAHDKFHKRLVKAWKDINEGCLRPYPVPKPLLMRILSLTRVIDVIYKNEDWYTHVKKPMKDKIASLLIDPMIV
What is the function of this protein?
Catalyzes the formation of beta-elemol, guaiol and bulnesol.
What are the official names of this protein?
Sesquiterpene synthase, SspiSesquiTPS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: CMC_DROME
Sequence: MPMHIPFPFNWIPTLPVARCQESPSLLKRAGTEKLREVFLKYASIQKNGEHYMTSEDFVRKFLGLFSESAFNDESVRLLANIADTSKDGLISFSEFQAFEGLLCTPDALYRTAFQLFDRKGNGTVSYADFADVVQKTELHSKIPFSLDGPFIKRYFGDKKQRLINYAEFTQLLHDFHEEHAMEAFRSKDPAGTGFISPLDFQDIIVNVKRHLLTPGVRDNLVSVTEGHKVSFPYFIAFTSLLNNMELIKQVYLHATEGSRTDMITKDQILLAAQTMSQITPLEIDILFHLAGAVHQAGRIDYSDLSNIAPEHYTKHMTHRLAEIKAVESPADRSAFIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGEIASGSKIRAWSVVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMMADKDGYNHPLTLLAAGAIAGVPAASLVTPADVIKTRLQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELLQRLFYVDFGGTQPKGSEAHKITTPLEQAAASVTTENVDHIGGYRAAVPLLAGVESKFGLYLPRFGRGVTAASPSTATGS
What is the function of this protein?
Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane (By similarity).  Necessary for gamma-aminobutyric acid (GABA) uptake in brain mitochondria in response to increased mitochondrial membrane polarization (PubMed:32200800).
What are the official names of this protein?
Calcium-binding mitochondrial carrier protein Aralar1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.