PharMolix/UniProtQA huggingface dataset:
Protein: MTNB_BACC3
Sequence: MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAETILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDSGAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: Y350A_MYCGE
Sequence: MNGNKLVFLPKKSYHQLFNITFSAMMLALAIITSLISEFISIPFFSQLKLTFDISVVFLVACAFFVSLGWSLTITLASALTSFFWNTNNVIGVLTVTLANLSTILFTRLYFCLFSKRRFCWIFVFLFTTLSNALLLTTLNGILITPLFWYYFGYVQTPNFLIVAEQYNKNTDFHFFFFGINNYWLGIFCLYSFFNLVKFGLVSCFGVPIMRSFQKFYWKRALAK
What are the official names of this protein?
Uncharacterized protein MG350.1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ECFA2_METHJ
Sequence: MEPLIELKDLEYAYPYASPALSNISLCIQRGEKIALVGSNGAGKSTLLLTLNGMIRPDKGTVTIYGKPVSYDRNSLRKIRQKIGFVFQDPDVQIIAPTVWQDVAFGPVNLDYSEEQVQQAVSNALHSVGLEGFEKRPPYHLSGGEKKRVAIAGILAMDPDVLILDEPTSMLDPAGSEDIMDLLDELNHQGKTIIISTHDVELAYPWADRIILMEKGRIIASGTPEEAFSDKELVRRARLKTPILLELSQELKSRGMKTPGTLPRTVLDIIRIIEHNHHGSIRLSDNGYGTIHVGDVDLISGSHIQAILARTSCDTIGVMGSRAKICARQWGLIPDISYAVIDKCILQAMNGRTSLILTTGGMVTRVFERVSMFNQTNNRSIPVRSLIGDEIPDDLSGI
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RCF1_PYRTR
Sequence: MSFGGPNSTPLPSSFDENADFYNENTIDKIWRRFREEPLVPLGCGLTVWAIVGATRSMRKGDHKMTNLYFRRRLYAQGFTIAVLVAGNMYWQKDRLKRKEYEKKVAEKDRMDKRDRWLRELEMRDEEDKAWKERMAKKARGAADEAVGVTQMVKEKTKELKDQTVGK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: EF1A_YEAST
Sequence: MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK
What is the function of this protein?
GTP-binding component of the eukaryotic elongation factor 1 complex (eEF1).  In its active GTP-bound form, binds to and delivers aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.  In the presence of a correct codon-anticodon match between the aminoacyl-tRNA and the A-site codon of the ribosome-bound mRNA, the ribosome acts as a GTPase activator and the GTP is hydrolyzed.  The inactive GDP-bound form leaves the ribosome and must be recycled by its guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) before binding another molecule of aminoacyl-tRNA.  Required for nuclear export of aminoacyl-tRNAs.  May also be involved in translational quality control by targeting cotranslationally damaged proteins to the proteasome.  Also exhibits actin filament-binding and -bundling activities and is involved in cytoskeleton organization.  Plays a role as a negative regulator of GCN2 kinase activity by inhibiting GCN2-mediated eIF-2-alpha phosphorylation in amino acid-repleted cells (PubMed:21849502).
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Eukaryotic elongation factor 1A, eEF1A, Translation elongation factor 1A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: NRDR_ANAMF
Sequence: MRCPFCNSVDTSVKNSRPSDCKMSVRRRRSCDSCNSRFTTVEELLLKPVKVLKKDGSVEAFDRQKLLTSIILATKKRPVTRDQIDMVVSNMFYKLEAIKGSVVPSGVIGGMVMESLFALDKVSYIRFASVYMNFSDVNDFSGIVERVQEVV
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NDK_YERPS
Sequence: MALERTFSIIKPNAVANNNIGAIYARFESAGFKIIAAKMLHLTKEQAEGFYAEHKGRPFFDGLVEFMTSGPIIVQVLEGENAVQRHRDIMGATNPDNALAGTLRADFADSFTANAVHGSDAVESAQREIAYFFAADEIFPRS
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UUP_HAEIN
Sequence: MALISLTNGYLSFSDAPLLDHAELHIEPNECVCLVGRNGAGKSTLLKIIAGDVLMDDGKIQYEKDLVVSRLEQDPPRNAQGNIFDYVAEGVGHLTDLLKEYHQISVQLEENYSDQILSQLEQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGGWLRKAALARALVCDPDVLLLDEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLVSYPGNYDLYLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKVMREERRQRRDVMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKTVMDNVADGKQDIEINGVKRHVLGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEEILTDYQGTLLIVSHDRQFIDNTATECYLFEGKGHLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIADPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKKNLVEGKA
What is the function of this protein?
Probably plays a role in ribosome assembly or function.  May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps.  Binds DNA and has ATPase activity.
What are the official names of this protein?
ATP-binding protein Uup.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with ribosomes.
Protein: KAD6_BOVIN
Sequence: MLLPNILLTGTPGVGKTTLGKELASRSGLKYINVGDLAREGQLYDGYDEEYDCPILDEDRVVDELENQMSEGGVIVDYHGCDFFPERWFHIVFVLKTDNSILYKRLENRGYNEKKLKDNIQCEIFQVLHEEALASYKEEIVHQLPSNKPEDLEDNINQILKWIEHWVKDHSS
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  May have a role in nuclear energy homeostasis.  Has also ATPase activity.  May be involved in regulation of Cajal body (CB) formation.
What are the official names of this protein?
Adenylate kinase isoenzyme 6, AK6, Coilin-interacting nuclear ATPase protein, Dual activity adenylate kinase/ATPase, AK/ATPase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.
Protein: HSLV_ALIB4
Sequence: MFDATTILAYKGKNKAVIGGDGQVTFGNTVLKGNATKIRTLYKDQILAGFAGSTADAFNLFDMFEGHLEACKGDLLKSVIAFSKEWRKDKVLRRLEAMMIVLNKEKIFILSGNGDVVEPEDGAIASIGSGGNFAISAARALAKHSSLDEEELVKESLMIAGELCIYTNQNIKILKLED
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABCAA_DICDI
Sequence: MTNNCKITFKNQLKALLGKAILLKKKKRKETITEFTQGIQYIIVLVILHYTIPNVITLNTYSPVGLGYPTSGFPLCYVSNVPFNQTSNLHLLLNSTQLPISQIVQFPNEQSLIDSYKSNPQSITYGISFNNIDYQNNILDYNILLNSTFQNTQLISIVQNLFLSTFAEIKGITTTTTTTLSSIEEFPNLTSSVSVSSYLYVIYLPLLFLFSLQQLLVTSVTERKNHIKEVMKVMGLKELVYWVTIIIVQTITNVINILLVMVVLYFTKTLTTSLNPVMLFLQFLLYSFSMVAIGIILSNLVDTPKTASAISSFLLLILVGVSCFYQFYLKSKTSSSWLRSILFLFSPCAFGEFLYKMGNDQQMMLTTNWSDPQVKISFLFLIIDIFLYFTIAWYITELYKDNTDENSITKSFTFFLSLSYWKSIFNLRSSSSSSSLPLLNNNNNCNNNNTSPSSSSSSQSSPLNKPLLSGDSDDDENDIGIRLVNLKKTYKNPITKETVNAVNDVSYTIKKGTILALLGQNGSGKTSTIGMLNGMRSPSSGDAFINGLSIKYDMDKIRENGIGLCHQSNILYDEFTCAEHIALYSRLKGLFVDGGGANGDNKRIMMDNFIMESLGEVNLVDKKDTQSIKLSGGMKRRLCLAISLIGNPSILLLDEPSSGLDSLSQHMICELLQRKKPNKTIILTTHNLDSAELLGDKICIMTSGKVKAMGSSLELKNQFNLGYILTIVYDKSLSLLQPPNINQQFESFFFNKFNDSTQSKQNLKNIQSFYNIFNNNNNENNSNNSDGSSSSSDSSSSKDVLLNIKNNNNNNNNNEERGFSSGQRDLELEYSLTHQSTDVITEFLEELESRQDEFKIKRISMSMTTLDEVFLKVSEEETINKNKQPTS
What are the official names of this protein?
ABC transporter A family member 10, ABC transporter ABCA.10.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ADC_PARPJ
Sequence: MDVKSVLSNAFAMPITSPAFPMGPYRFINREFLIITYRTDPDKLRAVVPEPLEIGEPLVHYEFIRMPDSTGFGDYTESGQVIPVSYKGVAGGYTLAMYLDDHPPIAGGRELWGFPKKLANPVLAVHTDTLVGTLDYGPVRIATGTMGYKHRQLDLAQQKKRLETPNFLLKVIPHVDGTPRICELVRYYLQDIDLKGAWTGPAALELAHHALAPVAELPVLEIVEARHLLADLTLGLGEVVFDYLDQPEANAR
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase, AAD, ADC.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: AMPP3_TALMQ
Sequence: MTSTDGILAGKYPAKAHARRVVEYLRQNGFQGDGVLYLEAQKTRMIEDNDSEQPFRQRRFFFYLSGCLLPDAHLTYHISTDKLTLFIPPLDPESVIWSGLPLSPAQAKELYDVDEVLYTTDVNPTLAHLASKVGFVFAIDGQISDDVSLKSFPDTDKVALKTAIEECRAVKDAYEVAMIRKANDVTSQAHVAVLKAAKSATNERELEAAFIGTCIAQGCREMAYHPIVASGTSSATLHYVNNDEPLIDSSTNKKKLNLLLDAAGEYKAYCADVTRTFPLSGKFSPESREIYDIVLEMQTESLAMLKEGVLWEDVHITAHRVAIKGLLKLGILRGSEEELLEKRVSVAFFPHGLGHYLGMDTHDTGGHANYADKDKMFQYLRVRGKLPAGSVITVEPGVYFCRFIIEPYLKDSELSKYIDADVLEKYWEVGGVRIEDNIHITKEGHENLTTAPKTADQVELMINGS
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase pepP, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: NCAP_I73A5
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVDGKWMRELVLYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRKTRGAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGPAVASGYNFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACNSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPAFSVQRNLPFDKSTIMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: YL47_SCHPO
Sequence: MKRFFSKLFSKSPTSGRVPSPDSDYSEEEQRLLAEENGYFQDSNEYVEPNIPAVYGSMIPVAQQLQQHHVHTPGESFADNASGYPVIKHELSELLRLGSPTVIAYLLQSSEQFSTVFTLGHLGKEYLAASSLSTMTAAISAFSIFQGVISSLDTLATQAFGANKPYNVAIYLQRCLLILAVLHIPVALIWLNLEHILIFLHQDPMVAHLCGRYMRVFILAAPGYAVFEALKRYLQAQGIFTPITYVLCFAAPLNILLNYLLVWHPTIGFGFLGAPVAVATTFWFQSICLILYICFSSTPIPWPGFSRQALKNLSPMLHFSFHGMLMIVTEWAAYEMTSLGAGYLGTAPLASQSILLTSTSLLFQIPFAFAVASSTRVGHLIGSGRANLARLCSRVAYSLALCISIFDGSLIFCFRDVWGSLFTSDPEVLAVVKDIFPILSLFIVTDGLNAVGGGLLRGTGKQYIGGLISIGSSYLFALPVTVFVVVYFNTGLKGIWCGMILSSVTAITCQFTVLFNTDWHRVLQEARHRLTHV
What are the official names of this protein?
Uncharacterized transporter C323.07c.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: DRC1_CHLRE
Sequence: MDELQSQTEREARILARRKRIQERLAALREGDHGGGKEGENKEEIGKGKQQIIESKRRLMRVKYRTDQDVSSVRVAGDDRENQHRIQEEQTRQDLRAKLLAEAEQSARQNAAVAMRWADLFSIEVPQDLYNEIESQRQACERIIASKDKLIGEIKGELKKKDDEFVKTLKRQAEDIDTLLQYMSRQFVEVQNAYKEELDEIENAFLQERSDLLESNRREMQELFDKRSRLEQDFMDRYLAAVEAYQSQLEGHRQMDAEEYHILKIRLETDIQNLEQHLEAMRATYQLNTEKLEYNYRVLKEREKENTQTIESQKKKLSRQRDILSSLKQRYAETDRRYRDDNMKLTDEYKRITEQFKDLQSKFRHFELVDTKKYKEVWGMKEADVAALVRQLLQADKVLHEQQLGWDWRPPDDAVFAPVHGDAGSGGGAAAAATGGAAGGAAAAGGVGPNGEEESEEDAAARVREAELAERLRDGRNWGALGLLCDEAGFLIDIKARNMIERLPKDEQGQVKAEAILRSLGIADGSAFDALLEALSADSNIELRAKGMVAPQGRGMAEEKSDRGGTAVLVHPDEAVRRLKAFVEVYGTGPSRGPGGGGGGGGGMSGPMRVQGAMRRAAEREQEFWSRMTHVISDKHTRVWGALEKQLEKYLALLQERAGSLRDVESLQHQNNELRALLNQYLSSRINDELQIPPTQII
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.  Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes.  Coassembles with DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules (PubMed:23427265, PubMed:25411337, PubMed:29167384, PubMed:23354437).
What are the official names of this protein?
Dynein regulatory complex protein 1.
What is the protein family that this protein belongs to?
Belongs to the DRC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: PSBL_TAXBR
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RIMP_STAAC
Sequence: MSKITEQVEVIVKPIMEDLNFELVDVEYVKEGRDHFLRISIDKEGGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFVSLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_PSEAE
Sequence: MWKSILAIALGAALGALLRWFLGLKLNSLLPSIPPGTLLANLVGGYVIGAAIAYFAQAPGIAPEWRLLIITGFCGGLTTFSTFSAEVVSLLQEGRLGWAAGAIATHVSGSLLMTLLGLFSMNWMLGK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPR2K_MOUSE
Sequence: MSYQEQQCKQLCQPLPVCPPPKPCSPPKCPEPCPPPKCPETCPPQPCQRKCPPVLEAPCQQKCPSKSK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.  All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
What are the official names of this protein?
Small proline-rich protein 2K.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_ECO45
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLDDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETLEWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_PROMH
Sequence: MRKLNPYFGEFGGQYVPEILIPALDQLEQAFIDAQNDPSFQQEFQDLLKNYAGRPTALTLCRNLTQGTRTRLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVATALACALLNMKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSSTLKDACNEALRDWSGCYERAHYLLGTAAGPHPYPTIVREFQRMIGDEAKAQILAREGRLPDAVIACIGGGSNAIGLFASFIPETSVQLIGVEPAGKGIETGEHGAPLKHGKLGIYFGMKSPIMQTEEGQIEESYSISAGLDFPSVGPQHAHLNSIGRADYVSVTDDEAIEAFKTLSRREGIIPALESSHALAYALKLIAQNPDKEQLLIVNLSGRGDKDIFTVNDILAARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PAN2_COCIM
Sequence: MEADWDEVSQVAVPPPGPHLLPTVASTVAFDDSQELLWVGNEFGRVSSFYGPELQRYTSVKAHASSEGQVRQFLFHDKGVISLSANSVHLASRCGLTQWHISHPEMTELRCMSFTAQPHKIIVAGLQSAMFIIDVEKGAIVDQLSTEYRYTIMKRSRYLCAATDTGSVNVLSLTDFSVVKSWKAHGAVINDMDARNDFLVTCGFSVRHAGSPIVDPLANVYDLKSLIPLPPIPFHAGAAFVRMHPRLQTTSFIASQTGQLQVVDLMNPNTINLRQANVAFMLGLEVSPSGEALAINDAECSIHLWGSPSKIHFNEIGKETEFSDIPTRPSMLDWSNDTPLNVIGMPYYHERLLSAWPSHLIFEIGNAPVPMDPAILPYLRPSEIGQYAQNPRKKRRYQVENTRLQSSTEVALAAPKFLSEKARELPNSKPEGAQEAVGALQGLKINGETKEDPLLKYSNVEIKYSKFGVDDFDFRYYNKTEFSGLETHIANSFTNSLLQLLKFIPLVRNLALHHVSTNCLCESCLLCEMGFLFDMLDKANGQNCQATNLLKTFSGFREAANLGLLEESLSNKSLSSAIQSVHRFFLNQIAHDYRTVYPNSDSLDNTLSTAAVESICCMFCRNEIVRPGNAFVTELIYPAADPKQAHRNQACRFSNILRSSIERETQNRGWCSTCRRYQQVSIRKTVQRMPLVLMLNAAINNSAHRRFWSIPGWLPEKIGVMIEDNQIQCYEGEQLRIRQQNNFEGLVVYELVGIVAEIDIVEQKKPHLVSFVDVSISAREPTKKSNWHLFNDFLVTGVSKEEVFSFNQGWKSPCTLAYQISTGRHGLDDSWKNELDTTLLFYEWSMNNRPPTDKCHILKSEEKPIAGTPIALDTEFVDLEKAEIEVKADGTQEMIRPSKSGLARVSVIRGSGNDEGVPFIDDYITIKDPIVDYVTQYSGIKPGDLDPRTSRHNLVALKVAYKKLWLLLNLGCVFVGHGLASDFRKINIQVPKAQTIDTQYLFFHPGKNRRLSLRYLAWAVFKEYIQEETTTTTSTSITTTTNPNIHDANTSTTTTTAITTTPPEGHDSIEDARMALRLWKKFKEYEDAGIVNQILEEIFREGVKVGFRPPARYPSQATPNPNNNNINNGVNPNGLSTPGSTNPISRLPLSGRNTPDFILPASASAAASVTGGPAGGGSSNGSMSGSTPSTPRQAFRRSTALTPSNGSFGGAKGLTFGGSPMR
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_SHEAM
Sequence: MFKGASAINLDAKGRIAIPTRYREPLLSAHEGKLVITVDIQANCLLIYPADEWSLIEAKLLKLSDTQPTERALKRMLLGYAHEIEMDSNGRLLLPPPLRQYAQLDKKAMLVGQLNKFELWDEAQWQAQIQSAQDVIRSEDLAANERLADFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYQ_PHOPR
Sequence: MMSESEARPTNFIRQIIDADLDSGKHKSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPEKEDIEYVESIKNDVNWLGFDWSGEICYSSNYFDKLYGFAVELINKGLAYVDELSPEQMREYRGNLTEPGKPSPYRDRSVAENLELFEKMKNGEVEEGIMSLRAKIDMASSFMVLRDPVIYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFQDNRRLYDWVLDNITIDCQPRQYEFSRLNLEYTVMSKRKLNQLVTDNLVSGWDDPRMPTVSGLRRRGFTSASIREFCKRIGVTKQENTIEMSSLESCIRDDLNENAPRAMAVLDPVKIVIENFTGDTEVLTVSNHPNNSEMGTREVPFTREIWIEREDFREEANKKYKRLVLGKEVRLRGAYVIKAERIEKDAEGNITTIFCSYDNETLGVNPSDGRKVKGVIHWVSADAGLPAEIRLYDRLFTVANPAAADDFVTVINPESLTVLNGFVEPSLKVAEAEKAFQFERIGYFCVDSKDSSAEKLVFNRTVGLRDTWAKMGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_ALKOO
Sequence: MKVRPSVKPICEKCKIIKRGGRVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: YOAI_SHIBS
Sequence: MNDQMFVETLIITSSFFAIAVVLVLSVLLIERTG
What are the official names of this protein?
Uncharacterized protein YoaI.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.