PharMolix/UniProtQA huggingface dataset:
Protein: RTC1_KLULA
Sequence: MFKRGSNRATSSSQGQQPENPPSLKYQSSSSRYSFHRQYNTGFGTSPFRISPKYKPDSRTPFSFDGTGNVGPESSLNEEESNARWRPSESSFDKRRTFHGAKYSLSIGKEVSSIDKINSPESRSLIIAGKSHLGIYTFDEDSKTITNVHDFLQTAKTNTGITKNTSSTLRRTTKKISTISDVKAGFYNHKNYVAICGTSTSVAIYDINKTSAIDNPVVTSLSEHTRSINSVDFNMVQTSLLISGGQDGCIKIWDLRSPKISTTRSDVSINTGSDSIRDVKWMPSYEFSNDTNGLSNRHFKFASVHDSGLLLKFDLRQPNQAEKKINAHSGPALCLNWHPHQDYIISGGRDGKCCLWYVGDKSNQVGNISSTNLNSSNPATHNLSSSYPLGLSNTLAFPELTINTARSMNKLKFRPKYETNVFNSLIGTSSMGEDSDVSVYSLARKYIPKNVIASSAPSVGFVWWDDDTIFNIDKQNTVTGWDISHEPTVLDNLPKNTIKWRDLDGDGILFLDQKPGGYLSQEETVLTPGSGENRKMPFTHRMSSATANSFTGGNNPNITSNTSSSAASFSKNPTLGMSQLHQGNVLGERSTMSKHAQSVNSKFSPSVNSSPWTNPYSSPHHNSIVSGSESALHAVNDSFLQSPYLIGLDFPHILNTIRNTRLAEFNRKVESAALLELKSSPTEVFKFLARELKFSYKYNSIETKDNGRELDSSSTHGSVDSKTNLMEKLGLSENNTWTHLIKYTKSHDSDEVISKGTELKTPVSDKSANIEKSATNHKAETNQDENSSCINSSNQVKTKNLIELITLCDKNAEIYIMLEDFSNYKIWLLMRDSLLWDLKVLTESMAVDVTADQEVNDQSSIDQPWKKNDSFTSLKEARQASVASGYSSYSATDLSSSVNTNNRHSFNEPTHLTQTPPVSHLKAQLQGSKETTTISRADSIQNSLQNDIIEIRKLRQSHGDRAELAIDEEEEGEEREELTKRAFEEDENNKQFINIPRRESGPSALMPSPSHVSSQSEIPSNPENHHQPRRPRTSFIDSFMSQLRSPGSSNVDADRESTGSKKSSMPSFSSSAATFLNSKKSQNANHNKLKSATEVSDILESEFATQKSWNGSVAKTTTQMSGITALMNETKKLENTITPPWSSRRLIHQLYEQSVASGNILLTMAILLLFQDMFQLVDTETVKNSIAEFTELLHRYELFEIAAELMKNCPYEDISSSSAGFSSIQLFCDKCNKPLVNESSKEKIIKERLEGNSSAMSRFGYWYCDSCSKRNTLCCFCNKPMKSLAISMLNCGHEGHFECLKKWFFDENMDVCPLGCPAILF
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: CYDA_ECOLI
Sequence: MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSGKQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLMAFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFNFETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKRSFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPDQEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSGSTDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRIMVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQPWAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGRYHFEQSSTTTQPAR
What is the function of this protein?
A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane.  It is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at low aeration.  Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron.
What are the official names of this protein?
Cytochrome bd-I ubiquinol oxidase subunit 1, Cytochrome bd-I oxidase subunit I, Cytochrome d ubiquinol oxidase subunit I.
What is the protein family that this protein belongs to?
Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEPA_PELTS
Sequence: MEWDKDRIRNFCIIAHIDHGKSTLADRLLEYTGALTGREMTEQVLDQMDLERERGITIKMQAVRLNYRARDGRDYQLNLIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGIEAQTLANVYLALEHNLEIIPVINKIDLPSADPERVKKEIEDVIGLDASEAVLASAKSGAGVEEILERIVTRIPPPGGQTGAPLRALIFDSHYDPYKGVVCYVRVVDGSVSNGMQIKMMATGREFEVSEVGIFKPYLASVGELRTGEVGFITAGIKNVKDSRVGDTITEAGRPAPVPLPGYRKATPMVFCGLYPVEAGEYEALKDALAKLKLNDASLTYEPETSEALGFGFRCGFLGLLHMEIIQERLEREYGLNLITTAPNVVYRVKTTAGETIEIENPSKLPPPGKIEFIEEPFVRAVIMAPKDYIGPVMELCQERRGVFTNMEYISVNRVMLNYALPLSEIIYDFFDQLKSRTKGYASLDYELDGYRQSDLVKLDVLIAGEVLDALSVIVHRDKAYQRGRHLVEKLRGLIPRHLFEIPIQAAVGNRIIARETVKAIRKDVLAKCYGGDVTRKRKLLEKQKAGKKRMKQVGRVEIPQEAFMAVLSVGDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TGT_DESOH
Sequence: MFQFETTTACPDTKARTGKMTTAHGDVATPVFMPVGTLATVKSLSPEDLVACGAQIILGNTYHLYLRPGCDIIDAFSGVHAFMGWNRPLLTDSGGFQVFSLAKLSRITEEGAAFQSHLDGSSHLLTPESVIDIQNRLGSDIQMCLDQCIAFPAEKGAARDAANLTTRWAGRCRNRWQETGGPSRCGLFGIVQGGMFDDLRADSAGRLVDLDFSGYAVGGLSVGEPIETRLAVAEHTLSLLPPDRPRYIMGVGTPAELVELVALGADMFDCVMPTRNARNGKLFTSFGAINIRNACHAKETGPVDPACTCYTCTRFSRAYLRHLFMSRELLAYRLATLHNLFYYINLINDARAAVAAGRFAAFRKAFYAAQQATGPTGKEPCAGS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RLMN_ECO57
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPAAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_STAA1
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOX9_ORYSJ
Sequence: MAAAVAMRSGSGSDGGGGGYDKAGMDSGKYVRYTPEQVEALERVYAECPKPSSSRRQQLLRDCPILANIEPKQIKVWFQNRRCRDKQRKEASRLQAVNRKLTAMNKLLMEENERLQKQVSQLVHENAYMKQQLQNPSLGNDTSCESNVTTPQNPLRDASNPSGLLTIAEETLTEFLSKATGTAVDWVPMPGMKPGPDSFGIVAVSHGCRGVAARACGLVNLEPTKIVEILKDRPSWFRDCRSLEVFTMFPAGNGGTIELVYMQMYAPTTLVPARDFWTLRYTTTMEDGSLVVCERSLSGSGGGPSTASAQQFVRAEMLPSGYLVRPCEGGGSIVHIVDHLDLEAWSVPEVLRPLYESSRVVAQKMTTAALRHIRQIAQETSGEVVYALGRQPAVLRTFSQRLSRGFNDAISGFNDDGWSVMGGDGIEDVIIACNAKKVRNTSTSANAFVTPGGVICAKASMLLQSVPPAVLVRFLREHRSEWADYNFDAYSASSLKTSSCSLPGLRPMRFSGSQIIMPLAHTVENEEILEVVRLEGQALTHDDGLMSRDIHLLQLCTGIDEKSMGSCFQLVSAPIDELFPDDAPLISSGFRVIPLDMKTDGTPAGRTLDLASSLEVGSTAQPTGDASMDDCNLRSVLTIAFQFPYEMHLQDSVATMARQYVRSIVSSVQRVSMAISPSRSGLNAGQKIISGFPEAPTLARWICQSYQFHLGVELLRQADDAGEALLKMLWDYEDAILCCSFKEKPVFTFANEMGLNMLETSLVALQDLSLDKIFDEAGRKALYNEIPKLMEQGYVYLPGGVCLSGMGRHVSFEQAVAWKVLGEDNNVHCLAFCFVNWSFV
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX9, HD-ZIP protein HOX9, Homeodomain transcription factor HOX9, OsHB2, OsHox9.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class III subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNP_THISH
Sequence: MTAIKKSFQYGQHTVTFETGEIARQASGAVLVNMADTVVLVTAVGLKDVAQGRDFFPLTVNYQERTYAAGRIPGGFFKREGRPTEKETLTSRLIDRPIRPLFPKGFMNEVQVIATVMSMNPEVDPDVPAMLGASAALALSGLPFKGPIGAARVGYLNGAYVLNPSMSELKHSDLDLVVAGTEKAVLMVESEAKLLSEEVMLGAVMYGHEQMQAAIKVINELAAEAGKPAWDWVAPEENVALKEAVAAACEAELTAAYQIAEKQARNQQVNALRDAVVAKLATGEEGAPSAEKVKGAFGALEKRIVRSRVLKGEPRIDGRDTRTVRPITVKTGVLPRTHGSALFTRGETQAIVVATLGTDRDAQLIEAIEGERRERFMLHYNFPPFCTGETGMVGSPKRREIGHGRLAKRGVQAVMPGEAECPYVLRVVSEITESNGSSSMASVCGTSLALMDAGVPLKAPVAGIAMGLIKEGDAFAVISDILGDEDHLGDMDFKVAGSKDGVSALQMDIKIDGITREIMEKALAQAKEGRLHILEKMNAVLSEPRTEVSAYAPRFTTLKIHPDKIRDVIGKGGATIRALTEETGTSIDISDDGTVKIASVDKAAGDEARRRIEELTADVEVGRIYEGRVVKIMDFGAFVTILPGRDGLVHISQISEERVESVSDRLTEGDLVKVKVLEVDKQGRIRLSMKEVG
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37A_YEAST
Sequence: MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L37-A, L43, Large ribosomal subunit protein eL37-A, YL35, YP55.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: RNH2_PSEPF
Sequence: MSKTSMQMGLDFTLVAEVEELVAGVDEVGRGPLCGAVVTAAVILDPNRPILGLNDSKKLTEAKREKLYDEICEKALSWCIARAEVEEIDELNILHATMLAMQRAVAGLHIQPKLAMIDGNRCPKLPMRSEAVVKGDSKVPAIAAASILAKVSRDREMAAFELIYPGYGISGHKGYPTPVHLEALVRLGPTPIHRRSFAPVRQAYEALEGLVQV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBSR_BACSU
Sequence: MDENPEFAAIEQARDLVIDSIAETMDLYGITRSVGILYGTMYMRDEMTLDEMREELQMSKPSMSTGVKKLQDLNVVKKTFHRGIRKHTFVAEKDFFKFFTNFFPPKWEREVQVNVTAIEEAQADLQKVLCKEDLDEDIKNEALQLYDQLESSKAYYDWLKRLAESVQTGEIFKFIPVETK
What is the function of this protein?
Negatively regulates the expression of the gbsAB and opuB operons.  Required to control expression of these genes in response to choline availability.  Also required to down-regulate glycine betaine production once cellular adjustment to high osmolarity has been achieved.
What are the official names of this protein?
HTH-type transcriptional repressor GbsR, Glycine betaine synthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the GbsR family.
Protein: TFCP2_XENTR
Sequence: MAWALKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVLALPIFKQEESSLPSENENKILPFQYVLCTATSPAVKLHEETLTYLNQGQSYEIRMLDNRKMGELPELNGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPTQLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPQEKEKYQPSYETTILTECSPWPEITYVSNAPSPGFNSSHNSFPIGEGNGSPNHQPEPPAPIVDVSAGLTPIQNLLPTSTPQEAQQWLHRNRFAAFSRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESQQLREQQQQHKHENGEAGNSAFYVYHAIYLEEMTAIELTEKIAQLFSISPHQINQIYKQGPTGIHVLISDEMIQNFQDESCFILDTMKAETNDSYHIILK
What is the function of this protein?
May function as a transcription factor.
What are the official names of this protein?
Transcription factor CP2.
What is the protein family that this protein belongs to?
Belongs to the grh/CP2 family. CP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: H2A_DROER
Sequence: MSGRGKGGKVKGKAKSRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: EFTS_XENLA
Sequence: MAALCNNLRAKLVSWQPVGLFHTGVRLLAADKDLLVKLRKKTGYSFMNCKKALEQCANDFKQAETWLHQQAQKEGWDKASKLQGRKTKEGLVGLLQDGSTSVMVEVNCETDFVARNSKFQQLVQQVAVSTLRHCQSHPENTSSYVKGFLCGDELLQLKADESLKDQLALAIGKLGENMIMKRAAWVKTPSDIFVGSYMHGILMADLPSLTNMTFGKYGALVICKDSDGNLKSNISEIGRRLGQHVVGMNPLLVGSLEDESGGETETKMLAQPFLLEPSLTVGQYLQPRGINVLDFIRFECGEEAESTESTPT
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MNMG_SINMW
Sequence: MADYDVIVIGGGHAGCEAAAASARLGARTLLITHKKDTIGVMSCNPAIGGLGKGHLVREIDALDGLMGRVADAAGIQFRLLNRRKGPAVRGPRTQADRKLYREAMQREIASIENLDVAEGDAFDLQTEDGVVCGAVMKDGRSFRAASVVLTTGTFLRGLIHIGDRKMPAGRVGEQPSVGLSETLARFGLQLGRLKTGTPARLDGRTIDWGRVGRQGPDENPVPFSFMTDAIVNRQIDCGVTRTTDATHKIIADNIHRSAMYSGQIEGVGPRYCPSIEDKIVRFGERDGHQIFLEPEGLDDDTVYPNGISTSLPEDVQDAFIRTIPGLEQVTILQPGYAIEYDHVDPRELEPSLGVRRMPGLFLAGQINGTTGYEEAGAQGLVAGLNAALRAAERAPFFFSRTDSYIGVMIDDLTSRGIAEPYRMFTSRAEYRLSLRADNADMRLTPVGIELGCVGNARLTRFQQWKSAYEAGRTLLQSLSVTPNEGKRFGLKLNQDGQRRTAFEILSYPDQSIEGLRPLWPELQAIATDVAAALEIDAAYAVYMERQAADIIGVQREESTAIPEAFDYESLPGLSNELKQKLAQQKPRNLSQAMKVDGVTPAAISLILSWLRREDRRSKRVGG
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRQ_ENT38
Sequence: MRLTAKQITWLKVILHLAGLLPFIWLFWAASQGYFSADPAKDIQHFTGRMALKFLLASLLISPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGINNLALLGSELISRPYLTLGIVSWVILFALTLTSTQYAQRKLGRRWQFLHNFVYLVAILTPIHYLWSVKILSPQPVIYALLALGLLAWRYKKFRQWWR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRI33_MOUSE
Sequence: MAENKGGGEAESGGGGSGSAPVTAGAAGPTAQEAEPPLAAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSSSAPAASVPAASVGSAVPGGAASTPAPAAAPAPAPAPAPAPAPAPAPAPAPGSSSGPPLGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDVQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGTSGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRLQQPPAPIPTTTATTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIPGIPRHSAPQYSMMQPHLQRQHSNPGHAGPFPVVSAHNPINPTSPTTATMANANRGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKSAHSFKSDQVKVKQEPGTEEEICSFSGAVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDTLTGLENHVKTEPTDISESCKQSGLSNLVNGKSPIRNLMHRSARIGGDGNSKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNMQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPVSIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKGDSEVAKAGKAVALYFEDKLSEIYSDRTFTPLPEFEQDEDDGEVTEDSDEDFIQPRRKRLKSDERPVHIK
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase.  Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway (By similarity).  May act as a transcriptional repressor (By similarity).  Inhibits the transcriptional response to TGF-beta/BMP signaling cascade (By similarity).  Plays a role in the control of cell proliferation (By similarity).  Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor.  Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade) (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM33, Ectodermin homolog, RING-type E3 ubiquitin transferase TRIM33, Transcription intermediary factor 1-gamma, TIF1-gamma, Tripartite motif-containing protein 33.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Nucleus. Note=In discrete nuclear dots resembling nuclear bodies.
Protein: YGFZ_SHIDS
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMTEDQHLQAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVREGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELRMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB16_ARATH
Sequence: MHAQRVARDLISGSPDEILGKILSFLPTHHAATTSVLSKRWRNLLPLVDKLELTEDHPSGRCSLGFPDFVEKTLALLDRPCSVIKKVHLNCDHLHGESRFYSWIRTVLERGVLDFHLESSRMYRVETEFFTSNTLVELTISGALYPEGELPPGGLFFPALKRLSIVLVAFADCDMYDDFVLGCPVLEELILYYADDDQPPGWNGKVSSPSIKRLTISHDYPDYPETHIYVWFDTPSLVYLDYSGHVARRYTAEMGSLEEARLNLLPWEQLIDSDEEDDDFDGYGPRWEKRSKDATGLIAMISNVKTLHLSSDSLEVIHSLCKVMPAFQNLLKLSFESDKERGWQVVPLLLNSSPNLETLVIKGLVHKVTSRCGDACLCIRKKTRGECCLLTCQVKVLKIIGYRGTCREQKQMSHFLANLKCLETVKVRVEVDHREDNDASNTYLRITNALMKLPRVSSNCRIHFL
What are the official names of this protein?
Putative F-box protein At1g21990.
Protein: PUR9_STRTD
Sequence: MTKRALISVSDKAGIVEFAQELKKLGWDIISTGGTKVTLDNAGVDTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLHSHLQAAKDNNIELIDLVVVNLYPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELSANGETTYETRQRLAAKVYRHTASYDALIAEYFTAQVGETKPEKLTLTYDLKQPMRYGENPQQDADFYQKGLPTAYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHMNPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHGVFLEIIIAPSYTDEALEILTTKKKNLRILELPFDAQDASEAEAEYTGVVGGLLVQNQDVVKESPADWQVVTKRQPTDTEVTALEFAWKAVKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRIAIDQAKGRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMIFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: JZT73_CHIGU
Sequence: MLVTLLETFSVVFQVANGDGNCVPRFQDDVEFCDNYILEAVTEASKMIAPRAREQKLCCGFNKFTHCVTTASKKCSEAADRVKRVLDTKMTSLGVHCPDTNKVCNGGVNTSVSANTVTVYLLFSLGYFFYMNKL
What is the function of this protein?
Probable secreted venom toxin.
What are the official names of this protein?
U35-theraphotoxin-Cg1a, U35-TRTX-Cg1a, Jingzhaotoxin-73, JZTX-73.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPD_RICPR
Sequence: MSYIIKEIEEAWQIKENILHDSSKLIKLKKILNESIASLNQGIIRVCEKQGNQWKVNEWVKKAILLYFITTESQLYNNNYNSWYDKVAPKFPADTDKNIFKEAAIRKVPGAIVRTGTYIAKNVVIMPSFINIGAYIDEGTMIDTWATIGSCAQIGKNCHISGGAGIGGVLEPLQAKPVIIEDNCFVGARSEIAEGVIVEEGSVISMGVFIGSSTKIVYRDTGEIIYGRIPAYSVVVPGILPPPEVGKPGLYCVVIVKQVDKTTRGKVSINDLLR
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.