PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_PSESM
Sequence: MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPSPKEISGILDQYVIGQERAKKVLAVAVYNHYKRLNQRDKKNDDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTRNILFICGGAFSGLEKVIQNRSTRGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFGLIPEFVGRLPVLATLDELDEAALIQILTEPKNALTKQYAKLFEMEGVDLEFRTDALKSVARRALERKTGARGLRSILEGVLLDTMYEIPSQSDVSKVVIDESVIDGTSKPLLIYENSEPPAKAAPDA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: G3P_SHIFL
Sequence: MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S20A1_PONAB
Sequence: MAALITSTTAATAASGPLVDYLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMYNSTQGLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVAKGQEGVKWSELIKIVMSWFVSPLLSGIMSGILFFLVRAFILHKADPVPNGLRALPVFYACTVGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREIKCSPSESPLMEKKNSLKEDHEETKLSVSDIENRNPVSEVGPATVPLQAVVEERTVSFKLGDLEEAPERERLPSVDLKEETSIDSTVNGAVQLPNGNLVQFSQAVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGEEVEKLTWPNADSKKRIRMDSYTSYCNAVSDLHSASEIDMSVKAEMGLGDRKGSNGSLEEWYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYDTGDVSSKVATPIWLLLYGGVGICIGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAIMAIFRYVILRM
What is the function of this protein?
Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis.  May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification (By similarity).  Essential for cell proliferation but this function is independent of its phosphate transporter activity (By similarity).
What are the official names of this protein?
Sodium-dependent phosphate transporter 1, Solute carrier family 20 member 1.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NEUR1_HUMAN
Sequence: MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
What is the function of this protein?
Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids.  To be active, it is strictly dependent on its presence in the multienzyme complex.  Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage.
What are the official names of this protein?
Sialidase-1, Acetylneuraminyl hydrolase, G9 sialidase, Lysosomal sialidase, N-acetyl-alpha-neuraminidase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Lysosome membrane; Peripheral membrane protein; Lumenal side. Lysosome lumen. Cell membrane. Cytoplasmic vesicle. Lysosome. Note=Localized not only on the inner side of the lysosomal membrane and in the lysosomal lumen, but also on the plasma membrane and in intracellular vesicles.
Protein: RAN_TETTH
Sequence: MVDNKQNVVAEFKLVLVGDGGVGKTTFVTRHQTGEFEKRYIATQGVNVSNMVLYTTKGPIRFNIWDTAGQEKLGGLREGYYIGANAAIMMFDVTSRITYKNIPKWHKDLTRICENIPIVLVGNKVDSKDRKVKARQITFHRKRSLQYYDVSAKSNYQYEKPFLWILRKLTGDPTLNLVEGIALVAPDTEHVMTEDQIKQLEMEQAEAMNLAQQGVLPDDEDDEFN
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran, GTPase Ran, Ras-like protein TC4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMPA_METPB
Sequence: MAGGIEIAFEPLSSRGRGGDVVVFVGDDLALSGPAAEILGRPGAELVVRAAASERFKGKAQSALVLPAPAGVEADRLVVIGLGSEKDRAKTDWTLLGGFTAGKVGGRSARVVLDWPGYAGSARDVADFTLGARLRSYRFDQYKTKKKDEDEAGAALSLLVADPSGAQAAARDAAAVAEGVILARNLVNEPPNVLYPEEYARRVSELTSLGVEIEILDVARMKELGMGALLAVAQGSAREPRVAIMRWNGADDPSEPPLALIGKGVVFDSGGVSIKSAGGMEDMKGDMGGSAAVVGTLHALAARKAKANVVGAIGIVENMPDGNSYRPSDIVTSLSGQTIEVINTDAEGRLVLADVLWHVQATYKPKAMIDLATLTGAIIVALGQDIAGLFSNDDALSAQITAAGEAAGEKVWRMPLIPAFDKAIDSKFADMKNTGGRHGGAATAAAFLKRYVNDVPWAHLDIAGVGMSSTPSEINRSWGAGWGVRLLDRLVREHYER
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CVC2_HCMVA
Sequence: MSLLHTFWRLPVAVFFEPHEENVLRCPERVLRRLLEDAAVTMRGGGWREDVLMDRVRKRYLRQELRDLGHRVQTYCEDLEGRVSEAEALLNQQCELDEGPSPRTLLQPPCRPRSSSPGTGVAGASAVPHGLYSRHDAITGPAAAPSDVVAPSDAVAASAAAGASSTWLAQCAERPLPGNVPSYFGITQNDPFIRFHTDFRGEVVNTMFENASTWTFSFGIWYYRLKRGLYTQPRWKRVYHLAQMDNFSISQELLLGVVNALENVTVYPTYDCVLSDLEAAACLLAAYGHALWEGRDPPDSVATVLGELPQLLPRLADDVSREIAAWEGPVAAGNNYYAYRDSPDLRYYMPLSGGRHYHPGTFDRHVLVRLFHKRGVIQHLPGYGTITEELVQERLSGQVRDDVLSLWSRRLLVGKLGRDVPVFVHEQQYLRSGLTCLAGLLLLWKVTNADSVFAPRTGKFTLADLLGSDAVAGGGLPGGRAGGEEEGYGGRHGRVRNFEFLVRYYIGPWYARDPAVTLSQLFPGLALLAVTESVRSGWDPSRREDSAGGGDGGGAVLMQLSKSNPVADYMFAQSSKQYGDLRRLEVHDALLFHYEHGLGRLLSVTLPRHRVSTLGSSLFNVNDIYELLYFLVLGFLPSVAVL
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.  Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
What are the official names of this protein?
Capsid vertex component 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RL11_ROSCS
Sequence: MAKKVTGVVKLQLPAGKATPAPPVGPALGGYGINIMAFVKEYNEKTASQAGSIIPVEVTIYSDRSFTITLKTPPAADLLRKAAGIEKGSGTPNRKIAGTITAKQLRQVAEQKMSDLNAQSIEAAEKIIAGTARSMGIKIVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: COX8B_RAT
Sequence: MPRLPPILRLLQAPEKYTVIPKARISSKPAKSPTSAMDQAVGMSVIIAGFMVPAGWVLSHLESYKRSSAA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8B, mitochondrial, Cytochrome c oxidase polypeptide VIII-heart, Cytochrome c oxidase subunit 8-1, Cytochrome c oxidase subunit 8H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: HISJ_ECOL6
Sequence: MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNSQGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQEIAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIVSYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTGMGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG
What is the function of this protein?
Part of the histidine permease ABC transporter.  Binds histidine.  Interacts with HisQMP and stimulates ATPase activity of HisP, which results in histidine translocation (By similarity).
What are the official names of this protein?
Histidine-binding periplasmic protein, HBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GATC_MYCA1
Sequence: MSQISRDEVAHLARLSRLALTDAELDSFAGQLDAILTHVSQVQAVDVTGVEPTDNPLKDLNVTRPDEPMPCLTQAEALAEAPEAVDGRFAVPQILGDE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: LY66D_HUMAN
Sequence: MKPQFVGILLSSLLGAALGNRMRCYNCGGSPSSSCKEAVTTCGEGRPQPGLEQIKLPGNPPVTLIHQHPACVAAHHCNQVETESVGDVTYPAHRDCYLGDLCNSAVASHVAPAGILAAAATALTCLLPGLWSG
What are the official names of this protein?
Lymphocyte antigen 6 complex locus protein G6d, Protein Ly6-D, Megakaryocyte-enhanced gene transcript 1 protein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cell projection, filopodium.
Protein: RNJ_MYCTO
Sequence: MDVDLPPPGPLTSGGLRVTALGGINEIGRNMTVFEHLGRLLIIDCGVLFPGHDEPGVDLILPDMRHVEDRLDDIEALVLTHGHEDHIGAIPFLLKLRPDIPVVGSKFTLALVAEKCREYRITPVFVEVREGQSTRHGVFECEYFAVNHSTPDALAIAVYTGAGTILHTGDIKFDQLPPDGRPTDLPGMSRLGDTGVDLLLCDSTNAEIPGVGPSESEVGPTLHRLIRGADGRVIVACFASNVDRVQQIIDAAVALGRRVSFVGRSMVRNMRVARQLGFLRVADSDLIDIAAAETMAPDQVVLITTGTQGEPMSALSRMSRGEHRSITLTAGDLIVLSSSLIPGNEEAVFGVIDALSKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRNVMPVHGTWRMLRANAKLAASTGVPQESILLAENGVSVDLVAGKASISGAVPVGKMFVDGLIAGDVGDITLGERLILSSGFVAVTVVVRRGTGQPLAAPHLHSRGFSEDPKALEPAVRKVEAELESLVAANVTDPIRIAQGVRRTVGKWVGETYRRQPMIVPTVIEV
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J, RNase J.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_BLOPB
Sequence: MSQYSFTSESVSEGHPDKIADQISDAILDSILAQDPRARVACETYVKTGIVIMGGEITTTAWVNMEEIARNTIRDIGYVHSDMGFDANSCVILSVINKQSSDIQYSIDHGNTSTLQRGAGDQGLMFGYATNETSVFMPAPITYAHRLIKRKSQVRKSGVLPWLGLDAKSQVTVAYEHGKIIGITAVVLSIQHACDIKLTDLKEAAMEEIIKPVLPNKWLTNNTIFLINPGGRFVIGGPISDCGLTGRKIIVDTYGGIGRHGGGSFSGKDPSKVDRSAAYGARYVAKNIVAAGLADRCELQVSYAIGVPHPISMSIETFGTEKISHDILMQLIKNFFDFRPYGLIAMLDLLRPIYKETAVYGHFGRECFPWEKIDKADLLRDAAGLKCTP
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_OENOB
Sequence: MSEERNTRKVYRGRVVSDKMDKTITVAVETYKNHPVYGKRVNYAKKFKAHDENNDAKLNDVVEIMETRPLSATKRFRLVRVVEKAVVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ISPH_ACTP7
Sequence: MNILLANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVDGLKAKGAVFVEELDEVPDDAIVIFSAHGVSQEVRQEAKRRGLKVFDATCPLVTKVHMQVARASKKGTKAILIGHEGHPEVIGTMGQYDNQDAGIFLVESVEDIAKLPVSSQDDLTFMTQTTLSIDDTSDVIEALKEKYPAIQGPRKNDICYATTNRQQAVRELAKQSQLVLVVGSKNSSNSNRLAELASRMGVPSKLIDGPQDIDPSWLDGVETIGITAGASAPEVLVQSVVEHLKTLGVTGVSNLEGCEENMVFEVPKELRIHEVK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PTH_YEAST
Sequence: MSGKWRLVLTGIGNPEPQYAGTRHNVGLYMLELLRKRLGLQGRTYSPVPNTGGKVHYIEDEHCTILRSDGQYMNLSGEQVCKVWARYAKYQARHVVIHDELSVACGKVQLRAPSTSIRGHNGLRSLLKCSGGRVPFAKLAIGIGREPGSRSRDPASVSRWVLGALTPQELQTLLTQSEPAAWRALTQYIS
What is the function of this protein?
Peptidyl-tRNA hydrolase involved in the recycling of tRNA-Lys from diacetyl-lysyl-tRNA-Lys and is important for mitochondrial function.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARLY_YEAST
Sequence: MSDGTQKLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTAGLQKLGLLTETELAKIHEGLAEIKKEWDADKFVRHPNDEDIHTANERRLGELIGRDIAGKVHTGRSRNDQVVTDLRIYCRDIVNDTLFPALKGLVEVLIKRAEGEIDVLMPGYTHLQRAQPIRWSHWLSSYATYFTEDYKRLGQILHRLNQSPLGAGALAGHPYGIDREFLAEGLGFNSVIGNSLVAVSDRDFIVELMFWGTLFMNHISRFAEDLIIYCTAEFGFIQLSDAYSTGSSLMPQKKNADSLELLRGKSGRVFGDLTGFLMSLKGIPSTYDKDMQEDKEPLFDCLTTVEHSMLIATGVISTLTVNKEKMEAALTMDMLATDLADYLVRKGVPFRETHHISGECVATAERLGLSGIDKLTLEQYQKIDSRFGQDLFETFNFEQSVERRDATGGTAKSAVLKQLDNLKSQLN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
Protein: E1BS_ADECT
Sequence: MDPLKICENYLTFRAIIRGSTLSPGFFRRWCFPALADVVGNIVEQEEGRFWQILPENHAFWGLLRRGFTVASFTEIITAAQLENRGRQLAFLAFISFLLRNWPSDSVVPEADRLDLVCAPAWSRMQIWSQTARLINDLQDSVLEEQGSAEEEECEEALLAGDSDDPLFG
What are the official names of this protein?
E1B protein, small T-antigen, E1B 19 kDa protein, E1B-19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1B 19 kDa protein family.
Protein: Y1970_STAAR
Sequence: MAMTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
What are the official names of this protein?
UPF0435 protein SAR1970.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: NUOCD_ECOK1
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DPB3_DEBHA
Sequence: MSSPMPQSSLNNSQVANMIDESNETPSTTPPMISNTNTPVPEIEMEEPNAPQDNTVAPNSIDGEKVQEENEDDDEQEEEEEEEEEEEESLSLPLSKIKKIFKMDPDYLAASQSAVYATGLATELFIQYFTEQSLVLAKMDKRKKLQYKDFSNAVASQDSLNFLSDTVPKTQPIGELINSKKVNVNSHDNNEIREIDNTEIDEIEVDEPVNATRKVKPLAKGQQTLNFSATNTATESINPMPIKKSVISDIVTTDNETEVTSKEATEEVEDQDVIMIN
What is the function of this protein?
As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon subunit C, DNA polymerase II subunit C.
What are the subcellular locations of this protein?
Nucleus.
Protein: ID2A_XENLA
Sequence: MKAFSPVRSVRKSSLTEHSLGIARSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQLTLDSHPSIVSLHHLPRVGGNTSRTPLTPLNTDISILSLQAAEFSSEFTDESKSLCP
What is the function of this protein?
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity.  Inhibits the activity of both neurogenic (neurod1/neuroD) and myogenic (myod1/myoD) bHLH factors.  May play a role in the regulation of the circadian clock.
What are the official names of this protein?
DNA-binding protein inhibitor ID-2-A, Inhibitor of DNA binding 2-A, XId2, Inhibitor of differentiation 2-A.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LEUC_LEPIC
Sequence: MKTMFEKIWEDHLVGELDAGSYLIYIDRHLIHEVTSPQAFEGLKLAGRKVRRPEATFATMDHNVSTRTRDLSLADPVSAIQMQTLKKNCDENGIRVYDFQNPDQGIIHVIAPEMGLTHPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLVQKRAKTMEIRVDGKLSDKVTAKDIILAIIGKIGTAGATGYVIEYRGSAIQALSMEARMTICNMSIEAGARAGLIAPDETTFNYIQGKDFSPKGVEWDLAVKKWKHYVTDEGAKFDRTVILHADEIAPMVTWGTSPSQVVSIKGVVPDPKDANDPVEKIGIESALKYMDLKSGQKIEDISINKVFIGSCTNSRIEDLRAAAATVKGKKVSSKVQAIVVPGSGRVKRQAEQEGLDKIFTAAGFEWRNPGCSMCLAMNDDVLEPGDRCASTSNRNFEGRQGKGGRTHLVGPEMAAAAAIEGHFVDIRNWK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y1295_METJA
Sequence: MRFDFHTHTVFSDGELIPAELVRRARVLKHRAIAITDHADFSNYKELIEKTTIAKEELKKYWDDIIVIVGVELTHIPPKSIPKMAKKAKDLGAEIVVVHGETVVEPVEEKTNYYASISEDVDILAHPGFIDKETAENLKENDIFVEITSRRGHNITNGYVANIAREFGLKTLINTDTHAPEDLIDDEFAKKVGLGAGLTNKELENTLLHYPKELLKRI
What are the official names of this protein?
Uncharacterized protein MJ1295.
Protein: NHAA1_SACEN
Sequence: MSKSARNRTRRNPDGQQGSARSFDFAEYLRTETVGGMVLLAAAALALVLANSPAEELYRTVRDFTVGPHFLHLDLTIGEWAKDGLLAIFFFVAGLELKRELVVGELADRKTATLPVVAALGGMVVPAVLAFAIGHGAPGAHAAWAIPVATDIAFALGVLSLTGSWMPTAARVFLLSLAVVDDLGAIVVIAVLFTSGLSVLALLAAAALCAVYWYAQKRRITTPFLYVPLAVATWIAVHSSGIHATIAGVALGLLTRVRRDLHETASPAMRLEHRLQPWSAGLIVPVFALFAAGVPVDGEALVAMTHDRVAIAVVVGLVVGKLVGIFGSSYLAVKIGIGAKPRGLRWRDLSALAMLGGVGFTVSLLIAELSLEGAAAERAKAAVLIASALASLLAAVMLLRRGRKVRNGDASA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBSD_PHOLL
Sequence: MKKGVLLNSEISAVISQLGHTDQITIGDAGLPIPSLAQRIDLALTQGIPSFISVLNVVTQEMQIEAAFLAEEIIGHNPLIHQLILTQIKELEKQQGNSITVDYISHNVLKEKTKHSRAVIRTGEHSPYANIILGAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICP55_SCHPO
Sequence: MSGYIRTLFIRNRFSNYRLRSQIIKYKYSNVSYLNKSALRCGQATDSTHPHILQPGELTPRISAQEYKTRRDRVASLLEDNDFMIVTSAPVRHMCGAAFYEYHQDPNFYYLTGCLEPNAVLLMFKNGASGSYDCSLYLPSKNPYIEKWEGLRTGSTLGKKLFQIENVYDSSLASSVINALGKKSNRIFYNYQTGYLSKMPAASAPEFIQDTLTKLFRTSTQRSVDELLHPLRSIKSTAELECMKEAANISSNVYREIMRKRFEKEAEMSAEFNYRFCIGGCDRSAYVPVVAGGKNGLTIHYTINNDIFRPDEMVLVDAGGEFGGYVTDISRTWPINGKFSTVQRDLYQAVLNVQKKCIKYCCTSNGWSLADIHFESVKLMHEELKQVGIHGTKREITDILYPHSIGHEIGLEIHDCSTNNGYQPLRKNQVITIEPGLYVPEEDGWPQWAQGIAIRIEDSVIVGDDKPFVLTSAAPKEIEEIEALKK
What is the function of this protein?
Aminopeptidase which cleaves preprotein intermediates that carry destabilizing N-ter amino acid residues after the mitochondrial processing peptidase (MPP) cleavage site and is thus critical for stabilization of the mitochondrial proteome.
What are the official names of this protein?
Intermediate cleaving peptidase 55.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.