PharMolix/UniProtQA huggingface dataset:
Protein: TRPDC_RUMGV
Sequence: MSQVIKKKRNTFMIGTEYILNSTQLEEAIKSFVHDFCAEKHEIHDQPVVVEAKEHQEDKIKQIKIPEKGRPVNEVVSEMMNEVYRYRGDANHPRFFSFVPGPASSVSWLGDIMTSAYNIHAGGSKLAPMVNCIEQEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLADSISWDAHKWLFQTYGCAMVLVKDIRNLFHSFHVNPEYLKDLENDIDNVNTWDIGMELTRPARGLKLWLTLQVLGSDLIGSAIEHGFQLAVWAEEALNPKKDWEIVSPAQMAMINFRYAPKDLTKEEQDILNEKISHRILESGYAAIFTTVLNGKTVLRICAIHPEATQEDMQHTIDLLDQYGREIYTEMKKA
What is the function of this protein?
Catalyzes the decarboxylation of tryptophan to tryptamine.  Tryptamine is a neurotransmitter that induces the release of serotonin, which is suggested to modulate gastrointestinal motility.  Therefore, the tryptophan decarboxylase from the gut bacteria Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) may influence host brain and behavior.  Has weak activity with tyrosine and phenylalanine.
What are the official names of this protein?
Tryptophan decarboxylase, Trp decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In vitro, tryptamine is excreted into the extracellular fluid, suggesting that the bacterium has the potential to excrete tryptamine in the host gut lumen.
Protein: H2BS1_PARAN
Sequence: MPSQKSPTKRSPTKRSPTKRSPQKGGKGGKGAKRGGKAGKRRRGVQVKRRRRRRESYGIYIYKVLKQVHPDTGISSRAMSVMNSFVNDVFERIAAEAGRLTTYNRRSTVSSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTTSR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1, sperm.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HIS7_STAES
Sequence: MNYQIKRNTEETQLNISLANNGTQSHINTGVGFLDHMLTLFTFHSGLTLSIEATGDTYVDDHHITEDIGIVIGQLLLELVKTQQSFTRYGCSYVPMDETLARTVVDISGRPYFSFNSKLSAQKVGTFDTELVEEFFRALVINARLTVHIDLLRGGNTHHEIEAIFKSFARALKISLAQNEDGRIPSSKGVIE
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNHA_MYCS0
Sequence: MTTVDKRPSSRGYGDWRLSDIPQYKDGISTYEFVRATHEADYRTHQAEPVAGRTFGFNGIGRLTEVALHMPTKYTLHDQSSQYKESPSFFQGLMGVPDRGPVDLAAFQRETEELATAFENNGIKVHWVDYPEEPANPYGPLMGHVFLSWGSIWRGGSVISRFGFLPGMVGVSEYLAKWAWNTLNIPPLVAITEGAMEPGACNMIADEVLVTCLSASYDQRGTDQLVAAISKTSGTEEFHNLQLRPAVEGFFNKATGACAHPDININAIDVGKLVVSPAALDWDARTWLYDNNFELIEADPDEQREFLAPCNVLLLEPGKVIAHADCHKTNQKIRDAGVEVIEVTGTEIRKACGGIKCRVMQINREPGPTLADVRNRVWR
What is the function of this protein?
Involved in the biodegradation of 2-Nitroimidazole (2NI) which is a natural antibiotic and an analog of the synthetic nitroimidazoles used for treatment of tuberculosis, Chagas disease (also called American Trypanosomiasis) and cancer.  Catalyzes the hydrolytic denitration of 2NI to produce imidazol-2-one and nitrite.  It is also active against the 2NI synthetic derivative benznidazole.  NnhA confers drug resistance to 2NI.
What are the official names of this protein?
2-nitroimidazole nitrohydrolase, 2NI nitrohydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
Protein: NANE_LISW6
Sequence: MNNSVKEKIKGGLVVSCQALSNEPLHSSFIMSKMALAAVQSGAVGIRANTTKDIKAIEEQVDVPIIGIFKNEYEGSEVFITPTYKEVKEICESGAQIVAMDATTRLRPHGEKLDEIIKTVRKEFPNILLMADTSSLEDVKYADALGFDFIGTTLYGYTEATTGKNISDNQFAYLKEVLKSTTTPIIAEGKIDTPEKAREVLALGCYSVVVGGAITRPQEITKRFINEMKKDHLGKS
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: ATPB_CORGL
Sequence: MTTALEEQNAQQAATAGRVVRVIGAVVDVEFPRGELPALYNALTVEVTLESVKKTVVLEVAQHLGDNLIRTIAMAPTDGLVRGAAVTDTARPISVPVGDVVKGHVFNALGDCLDDVSLNNNPEIERWGIHREPPSFDQLEGKTEILETGIKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMITRIAREFSGTSVFAGVGERTREGTDLFLEMEEMGVLQDTALVFGQMDEPPGVRMRVALSGLTMAEYFRDVQNQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGVLQERITSTKGRSITSLQAVYVPADDYTDPAPATTFAHLDATTELDRSIASKGIYPAVNPLTSTSRILEPAIVGERHYEVSQRVIGILQKNKELQDIIAILGMDELSEEDKITVARARRIERFLGQNFFVAEKFTGLPGSYVPLTDTVDAFERICNGDFDHYPDQAFNGLGGLDDVEAAYKKLTGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SCPB_LACDA
Sequence: MTSKIAQLQALLYVAGDGGIKKEQLRDLLQLADPEIESLAKRLQEKLASDLDCGLQLLEINDEYKLTTSGEVSDLVEAYFNKDLTKNISQSALEILAIVAYRQPITRIEIDEIRGVNSSGALQTLVWRGLVKAQGVKDAPGHPKLYVTTDYFLQYFGYKSLADLPVIENFEDSSFDADGQVDLFAENGTADEAFHKMEDL
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: E4PD_CITK8
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEISVVAINELADAAGMAHLLKYDTSHGRFAWDVRQEREQLIVGDDTIRILHERTLDALPWRELSIDVVLDCTGVYGNREHGEAHLAAGAKKVLFSHPGSHDLDATVVFGVNQEQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHSDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNQLLQKAAHGAFHGIVDYTELPLVSIDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAVGFK
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_ORITI
Sequence: MSSESKLILIGIISSPYGIRGQVAIKSFTDPASNILNYELKDYRKNIIKIHSAKILSKKIICNIDQIVTRTAAEQLTRTKLYIYKHELPQLPDSEYYVANLNGIKVKNLEGEIIGKINNICNYNAGDIIEVVYNDGKKIMYPFTNEIFPQITEDFVVIVPPEFI
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI44_BOVIN
Sequence: MASGGGAAFEELPHDGTCDECEPDEAPGAEEVCRECGFCYCRHHAEAHGQKFPRHHLAEYVHCAAQAWTPGARGDGAGEEAVEAPVENEKALENEAGEGIESEEDSEPEEESETEEESEDESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDKQLICVLCPVIGAHHGHHLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEEPGGTDED
What is the function of this protein?
May play a role in the process of differentiation and maturation of neuronal cells (By similarity).  May regulate the activity of TRIM17 (By similarity).  Is a negative regulator of PAX6 expression (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 44.
Protein: MINC_LARHH
Sequence: MSASADHTFDIKSARLNLFSIRLRSTRLADITRDLDNRFSADSPFSRTPAMLDVSQVNPVELDYRGLVARFAQYGIHLVGVRPTPAGLEGALDDAGLLPLGGDEALDESRLEDEPQPQTLVIDKPVRAGQQVYARGGNLVVLATVSAGAEVIADGDIHIYGSLRGRALAGARGQRDARIFVRSMQAELLSIAGIWRTLEQDLPAALASRPLQVLLESDKIVMRALPD
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: CENPA_CANGA
Sequence: MSTRQAVFERDVDEDRWPRSARGLAGVNTVFEGDSEINSKAMRLLEKTRHRRNLLNRREDRRRYLGGVKAKAIESDYYHRNQLPSSYDAGNDDFEPINNSHVESEEENKRLPEKYSLDKYVKRSRKQRDHRHIVAKPKEKRNFAPSKLAMYEIEKYQRSTALLIQKIPFAKLVKEVTEEFAGESQDLRWQSMAILALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI
What is the function of this protein?
Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes.  Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore.  Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
What are the official names of this protein?
Histone H3-like centromeric protein CSE4, CENP-A homolog, CENPA homolog.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres.
Protein: CYSD_ECOL5
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRINLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: Y1106_STAAC
Sequence: MEYEYPIDLDWSNEEMISVINFFNHVEKYYESGVTAGDFMGAYKRFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVTAKK
What are the official names of this protein?
UPF0223 protein SACOL1106.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: RS8_SHEWM
Sequence: MSMQDPIADMLTRIRNGQAAKHVSVTMPSAKLKIAIAKTLKEEGYITDYAVADEAKPVLEITLKYFQGQPVVETIQRVSRPGLRIYKGKDELPKVMGGLGVAIVSTSKGLMTDRTARQNGMGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: COAD_CLOAB
Sequence: MKVAVYPGSFDPITNGHLDIISRASKVFDKVIVGVLINPEKKGMFSVDERVDLIKRVIKPFNNVSVQSFSGLLVNFMENNDSNVMIRGLRSVGDFEYELQTSLMNKKLNPNVETVFMMTSLEFSFLSSTAIKQVAVFGGCIKELVPDEIIDDVLRKAKEFN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_HV1ZH
Sequence: MKVKGIQGNWQNWWKWGTLILGLVIICSAAENLWVTVYYGVPVWKDAETTLFCASDAKAYDTEKHNVWATHACVPTDPNPQELSLGNVTEKFDMWKNNMVEQMHEDVISLWDQSLKPCVKLTPLCVTLSCHNITIKDNNTNVDTEMKEEIKNCSYNMTTELRDKQRKIYSLFYRLDIVPIGGNSSNGDSSKYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDEEFEGKGPCRNVSTVQCTHGIRPVVSTQLLLNGSLAEGEVRIRSENFTDNAKIIIVQLVKPVNITCMRPNNNTRKSISIGPGRAFFATGDIIGDIRQAHCNVSRTEWNDTLSKVAAQLRKHFVNTSTDIIFANSSGGDVEITTHSFNCGGEFFYCNTSGLFNGTWLNGTSNNTWKIDTVNDTIILPCRIKQIVNMWQRVGQAMYAPPIKGVIKCVSNITGILLTRDGVGNNTSNETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVAREKRAIGMGAFFLGFLGAAGSTMGAASITLTVQARRLLSGIVQQQNNLLRAIEAQQHLLKLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKIICPTNVPWNSSWSNKSQSDIWDKMTWLEWDKEVSNYTQVIYNLIEESQTQQEINERDLLALDKWANLWNWFDISNWLWYIKIFIMIVGGLIGLRIVFAVLSIINRVRQGYSPLSFQTLTHHQREPDRPERIEEGGGEQDRDRSIRLVSGFLPLAWDDLRSLCLFCYHRLRDCALIAARIVETLIRRGWETLKYLGNLVIYWGQELKNSAINLLDTVAIAVADWTDRVIEVVQRAGRAFLNIPRRIRQGLERALL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: WNT4_CHICK
Sequence: MSPEYFLRSLLLIILATFSANASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDTLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELDKCGCDRTVQGGSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSNRALMNLHNNEAGRKAILNNMRVECKCHGVSGSCEFKTCWKAMPPFRKVGNVLKEKFDGATEVEQSEIGSTKVLVPKNSQFKPHTDEDLVYLDSSPDFCDHDLKNGVLGTSGRQCNKTSKAIDGCELMCCGRGFHTDEVEVVERCSCKFHWCCSVKCKPCHRVVEIHTCR
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors (Probable).  Plays an important role in embryonic development (By similarity).
What are the official names of this protein?
Protein Wnt-4.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MTGA_CITK8
Sequence: MSKGRFTPLASLRRLLLRILVVLAVFWGGGIALFSVVPVPFSAVMVERQISAWLQGDFGYVAHSDWAGMDAISPWMGLAVIAAEDQKFPEHWGFDVSAIEKALAHNERNENRIRGASTLSQQTAKNLFLWDGRSWLRKGLEAGLTVGLETVWSKKRILTVYLNIAEFGDGVFGVEAASQRYFNKPASRLSMSEAALLAAVLPNPLRFKANAPSGYVRSRQAWILRQMRQLGGESFMTRNHLY
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HIS2_BRUA2
Sequence: MSQFTLADLERIVAERASVTDGTSYTASLVAKGQPKAAQKLGEEAVETVIAAVSGDRAGVVSESADLLYHLAVVWNIAGVALEDVLQELQRRTAQTGLAEKASRPKG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_SYNP6
Sequence: MAEQTQLAPAAFHLPDLVAIQRNSFRWFLEEGLIEELESFSPITDYTGKLELHFLGKQYKLKRPKYDVDEAKRRDGTYSVQMYVPTRLINKETGEIKEQEVFIGDLPLMTDRGTFIINGAERVIVNQIVRSPGVYYKSERDKNGRLTHNASLIPNRGAWLKFETDKNGLVWVRIDKTRKLSAQVLLKALGLSDNEIYDKLRHPEYYQKTIDKEGQFSEDEALMELYRKLRPGEPPTVSGGQQLLESRFFDPKRYDLGRVGRYKLNKKLGLNVADTVRTLTSEDILAAIDYLINLELDLGGCEVDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIRERMTVSDSDSLSPASLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFAVRDIHPSHYGRICPIETPEGPNAGLIGSLATHARVNDYGFIETPFWRVEEGRVRKDLAPVYMTADQEDDLRVAPGDVATDDAGYILGTTIPVRYRQDFTTTTPERVDYVALSPVQIISVATSLIPFLEHDDANRALMSSNMQRQAVPLLRPERPLVGTGLEPQAARDSGMVITSPVDGTISYVDATHIEVTADTGEKYGYALQKYQRSNQDTCLNQRPIVFEGDRGQRGQVIADGSATEKGELALGQNILVAYMPWEGYNYEDAILISERLVYDDVYTSIHIEKFEIEARQTKLGPEEITREIPNVGEDALRQLDENGIIRVGAWVESGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPNGEKGRVVDVRLFTREQGDELPPGANMVVRVYVAQKRKIQVGDKMAGRHGNKGIISRILPCEDMPYLPDGTPLDIVLNPLGVPSRMNVGQVFECMLGWAGQLLDARFKVTPFDEMYGAEASRLTVNAKLSEAREQTGQPWVFSDDEPGKIQVYDGRTGEPFDRPVTVGRAYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRFGEMEVWALEAYGAAYILQELLTVKSDDMQGRNEALNAIVKGKAIPRPGTPESFKVLMRELQSLCLDIAVYKASTEDYEEDKEVDLMADVNQRRTPSRPTYESMSVGDIDDDDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MYBPH_RAT
Sequence: MTGKATPEASVSTSEGTAPEPAKVPTPEPSGQVAASESTGQEQAPEPQKQPQAQDPAAHEAPATPATTKPEAPSEDVPSAPLQLTLEDVSHSSLTVSWEPPEDLGSWGSRAMCWSSVREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVNSAGAGPPAVLDQPVHIQEITEAPKIRVPRHLRQTYIRQVGESVNLQIPFQGKPKPQASWTHNGHALDSQRVNVRSGDQDSILFIRSAQRSDSGRYELTVRLEGLEAKAAIDILVIEKPGPPSSIKLLDVWGCNAALEWMPPQDTGNTELLGYTVQKADKKTGQWFTVLERYHPTTCTVSDLIIGNSYSFRVFSENLCGLSDLATTTKELAHIHKAAITAKPREFTERDFSEPPSFTQPVADRTSTPGYSTQLFCSVRASPKPKIIWMKNKMSIQGDPKYRAVSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEPAVDCRLEVKASATH
What is the function of this protein?
Binds to myosin; probably involved in interaction with thick myofilaments in the A-band.
What are the official names of this protein?
Myosin-binding protein H, MyBP-H, H-protein.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. MyBP family.
Protein: PYRB_STRT2
Sequence: MAIADGKVSLKHLVTMETLTNEEVLGMIRRGGDFKNGRADFQLDRQYFAANLFFENSTRTHKSFEVAEKKLGLDVIEFDAGTSSVNKGETLYDTILTMSALGVDICVVRHSEVDYYKQLIDSRTIQTSIVNGGDGSGQHPSQCLLDLMTIYEEFGTFGNLKICIAGDITHSRVAKSNMRILKRLGAQIYFAGPTEWYSSEFDVYGQHVAIDDVIEDLNVLMLLRVQHERHRNDKGFSKEEYHTLYGLTEERYAKLADQAIIMHPAPVNRDVEIADSLVEAPKARIVTQMQNGVFVRMAIIEAILNGKA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: LPLT_YERPY
Sequence: MSQDVLADKPLLSRSMVAVLCAQFFSAFGDNALLFATLALIKQQLYPDWSQPILQMAFVATYIVLAPFVGQIADGFAKGRVMMVANGLKLAGALVICFGLNPFLGYSLVGVGAAAYSPAKYGILGEITSGEQLVKANGMMEASTIAAILLGSVAGGILADWHLMAALGVCALVYAIAVIANLFIPRLAAARSGASWRPRAMTGSFFTACRLLWQDSETRFSLAGTSLFWGAGVTLRFLLVLWVPVALGIADNATPTLLNAMVAIGIVVGAGAAARFVTLKTVKRCLPAGVLIGVMVTIFSLQNSMPMAYLLLIIIGILGGFFVVPLNALLQERGKHSVGAGNAIAVQNLGENTAMLFMLGLYSLVVKLGAPVVAVGVGFGVVFALAIALLWGWQWRQQRQKTRQPE
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEOD_PROMH
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLQDVRQVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYAKELITDFGVKVIIRVGSCGAVLPDVELRDVVIGMGACTDSKVNRLRFKDQDFAAIADFELVQNAVSAAKAKDIKVRVGNIFSADLFYSPDPEMFDVMEKYGILGVEMEAAGIYGVAAEYGARALTICTVSDHIKKGTQTTSEERQTTFNEMIEIALESVLLLED
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: SAHH_MYCLB
Sequence: MTTTENSLMPDVRNGIDFKVADLSLANFGRKELDLAEYEMPGLMSLRHEYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPYGTPEEPKGVPVFAWKGETLEEYWWAAEQMLTWPDPDKPVNMILDDGGDATMLVLRGVQYEKAGVVPPAEVDDSAEWKVFLNLLRKRFETDKGKWTKIAKSVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDSLIGGKNVLICGYGDVGKGCAEAAKGQGARVTITEIDPINALQALMEGFDVKRVEDVIADSDIVVTATGNKDIILLEHMKAMKDHAILGNIGHFDNEIDMAALERSGATRLNIKPQVDLWTFGDSGKSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTKNDDYDNEVYRLPKHLDEKVARVHVEALGGQLTKLTKDQAEYLGVDVDGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.