PharMolix/UniProtQA huggingface dataset:
Protein: SPEE_SHIFL
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFQLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDALASQPS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_ECO57
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVALYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U661_DORVU
Sequence: MSKLLVLLMTTALATLAQAISFDCSDKPPECQNDPGCCFDIGITTF
What is the function of this protein?
Probable toxin.  Does not show insecticidal, antimicrobial and antiparasitic activities.  Does not induce increase in intracellular calcium in mouse DRG neurons, suggesting that it does not induce pain.
What are the official names of this protein?
U-limacoditoxin(6)-Dv61, U-LCTX(6)-Dv61, Vulnericin.
What is the protein family that this protein belongs to?
Belongs to the limacoditoxin-6 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLC3A_XENLA
Sequence: MAQAGLLIWLFFTILLLDLTCTQSAKLKTQKDHRSKEKDGDLKTQIDKLWREINSLKEMQALQTVCLRGTKIHKKCYLSFEETKHFHEANEDCIAKGGTLAIPRDSEENNALRDYGKKSLHGSGEFWLGINDMVNEGKFVDVNGVAITYFNWERIPKGGKRKNCALLNQASQGKWVDEVCRSLKKYICEFIIP
What are the official names of this protein?
C-type lectin domain family 3 member A homolog, C-type lectin superfamily member 1 homolog.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_ROSDO
Sequence: MALKSYKPTTPGQRGLVLIDRSELWKGRPVKALTEGLSKHGGRNNTGRITMRRKGGGAKRLYRIVDFKRNKMDVAATVERIEYDPNRTAFIALVKYEDGEQAYILAPQRLAVGDTVVASQKADIKPGNAMPFSGMPIGTIIHNIEMKPGKGGQIARAAGTYAQFVGRDGGYAQIRLSSGELRLVRQECMATVGAVSNPDNSNQNYGKAGRMRHKGVRPSVRGVVMNPIDHPHGGGEGRTSGGRHPVTPWGKPTKGAKTRNKKKASSQLIIRSRHAKKKGR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GTF3_STRGN
Sequence: MKVNITNLYGMSGQSTALIAQNDVTKLAKQLGFNELSFYFYDIYSDSQSELSRRLDGIMASVGYGDVVIYQSPTWNGREFDQAFISKLKILQAKLITFIHDVPPLMFPSNYYLMPEYIDMYNQSDAVIVPSEQMRDKLLAEGLTVNKILIQRMWDHPYDLPLHQPQFAPKLYFAGSVERFPHLINWSYATPLEIFSPEEESNPEANVSYCGWVSRPELLLELSKGGLGLVWGVEDNPADEPEYYGLNISHKSATYLAAGIPVIVPSYLSNAELIRERGLGFVVDSLEEASRIVENLTVEEYQDMVERVRKFSFLLKEGYFSKKVLIDAVMEVLS
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required to export GspB, a serine-rich repeat cell wall protein encoded upstream in the same operon.
What are the official names of this protein?
Glucosyltransferase 3, Sugar transferase Nss.
What is the protein family that this protein belongs to?
Belongs to the Gtf3 glucosyltransferase family.
Protein: TMEDA_DROVI
Sequence: MLKVLYVIFTIFGYIWPIYSVMFHLTPNTQKCLKEDIQANQLVMGEYEVSDVPGQIIDYIARDTKGHILSQKEHITKGKFSFMSEVYDAYEICFISKVPPHQRGISQEVSLVTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFALMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLIE
What is the function of this protein?
Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo.  Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected (By similarity).
What are the official names of this protein?
Transmembrane emp24 domain-containing protein bai.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SYP_ECO5E
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIKKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFTAGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_COREF
Sequence: MLIPKRVKYRRQHRPTRSGISKGGNRVTFGEYGIQALEPAYITNRQIESARIAINRHVKRGGKVWINIFPDRPLTQKPLGVRMGSGKGPVEKWVANVKPGRILFEMSYPDEAMALEALRRAGQKLPCKVRIVKREDQL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RUVC_CAMJJ
Sequence: MNLKILGIDPGSRNCGYAIMEANKGKNILIEAGLIKIKPSTLQYQITELCEGLDLIFKNHSFDEVAIEDIFFAYNPKTVLKLAQFRGALSLKILQIHGDFAEYTPLQVKKAVTGKAKATKEQVAFMVKRLLGLSKDIKPLDITDAIAVALTHAANLRVRV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MURC_DEIGD
Sequence: MTDSPPCSSDSASSVPSQLHYHLMGIGGIGVSAFARLLAARGVRVSGCDTQPSELTEQLVREGIPVALGHDPAHVTGVDVLIASEAVPKNHPELVAARGAGVEVRPRMALLDELLRAGPSVGVIGTHGKTTTTSMIAVAMQGAGLDPAAFVGGIVPEFGSNVRLGTGPFVAEVDESDRGFAVLSCETAVFTNAEDDHVGGNQATYWETVEQQHAAFARFVGQARRVLYCADWPGLDQLVTTSGERLNYGLAEGADYRAVDLRPDAEGTTFTVARRGEVLGEARVGLPGLHNVLNALAALAVTDLYGGNFQTAAAALAAFRGPGRRWQRIGELNGALIIDDYAHNATKVAAAVQAARQTGRRVRVVFQPHRYLRTQQSWPRLADALMGADEVLVLDIATASEPPIPGIHATLVSDRMAQSGHTGVRYAPDRAEVVRYLRETACADDVIVTMGAGDVWKLSRELASV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y205_BRUME
Sequence: MPLRPALHLRTGKLRQTPTHNEPDGWAGQPLSAAAAHRGVCPMSDVMTANRRSFLAEDGKETIVRTDDLVRDFDLGHRPEGGRLVLRAVDKVSLTIRRGETLGLVGESGSGKSTIGRMLVGLLPYTSGNIELFGQKIEPRAKAAAWKPLRRRVQFVFQDPHAALNPRMRVGTAIAEPLDVAGNLTRKERSARVDELMELVGLPTSFARRFPHEFSGGQRQRIVIARALALNPEILVCDEAVASLDVSMQAQIVNLLKDLQDQLGLSHLFIAHDLAVVRAVSHRVAVLYAGQIVETGPRTALYSDPLHPYSRALLDSVPRARRGAPRSIIAGEVPSLLNKPKGCAFCPRCPKAMDICRDVPPPLRVIGDREVACHLY
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative peptide import ATP-binding protein BMEII0205.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: S7A13_HUMAN
Sequence: MDRGEKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFLGSGVVAGQALLLAEYSIQPFFPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNLLISIFKSSRPIYLASQEGQLPLLFNTLNSHSSPFTAVLLLVTLGSLAIILTSLIDLINYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVHYVYVLLLVLSGLLFYIPLIHFKIRLAWFEKMTCYLQLLFNICLPDVSEE
What is the function of this protein?
Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner.
What are the official names of this protein?
Solute carrier family 7 member 13, Sodium-independent aspartate/glutamate transporter 1, X-amino acid transporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSAJ_PANGI
Sequence: MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRFFPDALTFPFF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HEM6_PARXL
Sequence: MTDSSYDAQAVRSWLQGLQTQIADTLGAFDGTPFATDAWQRAPGEKLRGGGYTRILEGGNFFERAGIGFSDVAGDALPASASAARPQLAGRGFEAMGVSLVLHPHNPHCPTVHMNVRLLIATKAGEEPVFWFGGGMDLTPFYGYEEDAQHFHRTCRDALQPYGADLYPSFKRWCDEYFFLRHRNEPRGIGGIFFDDFSAPGFDQSFAMLRSVGDAFLKAYLPIIEKRRNIPYGQAERDFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPVVNWRYNWQPEPGTPEARLYSDFLVPREWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3M_POLOR
Sequence: MNLILMMILISSLISTILAIVAFWLPQMNPDMEKLSPYECGFDPLGSARLPFSMRFFLVAILFLLFDLEIALLLPLPWSTHLDPTLMLMWAFTIIILLTIGLIYEWLQGGLEWAE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PXL2A_BOVIN
Sequence: MGMWSIGAGAIGVAALALLLANTDMFLAKPEKAALEYLEDIDLKTLEKDAVTFKAKALWEKNGAVIMAVRRPGCFLCREEATDLSSLKPKLDELGVPLYAVVKEHIKNEVKDFQPYFKGEIFLDENKKFYGPQRRKMMFMGFVRLGVWQNFFRAWNGGFSGNLDGEGFILGGVFVMGPGKQGILLEHREKEFGDKVNLTSVLEAARKIRPQTSASEKQ
What is the function of this protein?
Involved in redox regulation of the cell.  Acts as an antioxidant.  Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation.  May affect bone resorption and help to maintain bone mass.  Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.
What are the official names of this protein?
Peroxiredoxin-like 2A, Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes, Protein PAMM, Redox-regulatory protein FAM213A.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Secreted from mature adipocytes but not from preadipocytes.
Protein: PCDG4_MOUSE
Sequence: MAAPYKSDRRGLIWICIFLGSLCDIRAEQIRYSVPEELERGSVVGNLAADLGLEPGKLAERGVRIVSRGKTQLFALNPRSGSLVTAGRVDREGLCDRSPKCTANLEILLEDKVRILAIEVEIIDVNDNAPSFGAQQREIKVAESENPGTRFPLPEAFDLDIGVNALQGYQLSSNDHFSLDVQSGPDGIKYPELVLENALDREEEAVHHLVLTAFDGGDPVRSGTATIQVTLVDTNDNAPVFTQPEYHISVKENLPVGTRLLTIKATDPDEGVNGEVTYSFRNVREKISQLFQLNSLTGDITVLGELDYEDSGFYDVDVEAHDGPGLRARSKVLVTVLDVNDNAPEVTVTSLTSSIQEASSPGTVIALFNVHDSDSGENGLVTCSIPDNLPFRLEKTYGNYHRLLIHRTLDREEVSDYNITITATDQGTPPLSTETYISLQVVDINDNPPTFTHASYSAYIPENNPRGASILSITAQDPDSGENAQVIYSLSEDTIQGAPMSSYVSINSNTGVLYALRSFDYEQFQDLKLLVTARDSGTPPLSSNVSLSLSVLDQNDNTPEILYPTIPTDGSTGVELTPRSADPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVTVQDHGQPPLSATVTLTIAVSDNIPDILADLVNINAPIDQEDSDITLYLVVAVAAVSCVFLAFVIVLLIHRLRRWHSTRLLQAAGNGLSSLPASHFVGVDGVHAFLQTYSHEVSLTADSGKSHLIFPQPNYADTLISQESCGKSDPLLVSQDLLEIKGDSSLQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity).
What are the official names of this protein?
Protocadherin gamma-A4, PCDH-gamma-A4.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SOT1_ARATH
Sequence: MAGKSDLPVIARDDNLSEETKTLISSLPTYQDSHVKLCKYQGCWYYHNTLQAVINYQRNFQPQDTDIILASFPKSGTTWLKALSVAIVERSKQPFDDDPLTHPLLSDNPHGIVPFFEFDMYLKTSTPDLTKFSTSSPRLFSTHMPLHTFKEGLKGSPCKVVYMCRNIKDVLISDWHFRSKYSNNEVSRSTLESMFESFCGGVSFYGPFWDHALSYWRGSLENPKHVLFMRYEEMKTEPCVQVKRLAEFLGFPFTKEEEDSGSISKLLELCSLGNLSGLEVNKTGKTWMNYDYKSYFRKGEVGDWKNHLTPEMENKIDMIIEEKLKGSDLKF
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor.
What are the official names of this protein?
Cytosolic sulfotransferase 1, AtSOT1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNW_BACAH
Sequence: MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNMMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDIAELEIDFLISSANKCIQGVPGFGFVIAQRDELLKCKGQARSLSLDLYDQWETMENQNGKWRFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVNEKYQSPIITSFIYPEGNFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: NSP3_ROTJ1
Sequence: MAELVCDALATLTRNTYGDNDESAKFCRMFRTMIRDSGLYGNIENWRAAFYRERLPKRMSHSTVSIQLDNLEREVLKIRAEGFCQGYTRKERTLNAFDLSDDGKGNTIIKPTTHLSSIILQNSYNSAFKLPKIPDGLLEKTRYELEEEKKNNDILKQKIKELENTISQLENYENEAKASQFVLEHLKFTNESLKIQRDEAQICLIGLCNKFGLQCEIDNSIHVTESDKKGKRKGRKNRRIEVSFGAPGHDLTEQISTLSDVE
What is the function of this protein?
May play a role in stimulating the translation of viral mRNAs.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: NUAK2_MOUSE
Sequence: MESVALLQRPSQAPSASALASESARPLADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYTTGVGEQEALREGGHPSGDFGRASMADWLRRSSRPLLENGAKVCSFFKQHVPGGGSTVPGLERQHSLKKSRKENDMAQNLQGDPAEDTSSRPGKSSLKLPKGILKKKSSTSSGEVQEDPQELRPVPDTPGQPVPAVSLLPRKGILKKSRQRESGYYSSPEPSESGELLDASDVFVSGDPVEQKSPQASGLLLHRKGILKLNGKFSRTALEGTTPSTFGSLDQLASSHPAARPSRPSGAVSEDSILSSESFDQLDLPERLPETPLRGCVSVDNLRGLEQPPSEGLKRWWQESLGDSCFSLTDCQEVTAAYRQALGICSKLS
What is the function of this protein?
Stress-activated kinase involved in tolerance to glucose starvation.  Induces cell-cell detachment by increasing F-actin conversion to G-actin.  Expression is induced by CD95 or TNF-alpha, via NF-kappa-B.  Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.  Phosphorylates LATS1 and LATS2.  Plays a key role in neural tube closure during embryonic development through LATS2 phosphorylation and regulation of the nuclear localization of YAP1 a critical downstream regulatory target in the Hippo signaling pathway.
What are the official names of this protein?
NUAK family SNF1-like kinase 2, Omphalocele kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: UBX_DROPS
Sequence: MNSYFEQASGFYGHPHQATGMAMGSGGHHDQTASAAAAAYRGFPLSLGMSPYANHHLQRTTQDSPYDASITAACNKIYGDGASAYKQDCLNIKADAVNGYKDIWNTGGSNGGGTGGGGGGGGAGGNASNGSNAGNAANGQNNAAGGMPVRPSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSAGGGGQSGQSGAPGVGVGVGVGVGAGAGTAWNANCTISGAAAAQTAAASSLHQASNHTFYPWMAIAGKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQKAAAAAAAAAAVQGGHLDQN
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Binds the consensus region 5'-TTAAT[GT][GA]-3'.  This homeotic protein controls development of the cells in the posterior thoracic and first abdominal segments.  It activates the synthesis of the decapentaplegic (DPP) growth factor (By similarity).
What are the official names of this protein?
Homeotic protein ultrabithorax.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: O11H7_HUMAN
Sequence: MNNSQISTVTQFVLLGFPGPWKIQIIFFSMILLVYIFTLTGNMAIICAVRWDHRLHTPMYVLLANFSFLEIWYVTCTVPNMLVNFFSKTKTISFSGCFTQFHFFFSLGTTECFFLCVMAYDRYLAICHPLHYPSIMTGQLCGILVSLCWLIGFLGHSISIFFIFQLPFCGPNIIDHFLCDVDPLMALSSAPTHIIGHVFHSVSSLFINLTMVYILGSYTLVLRTVLQVPSSAGWQKAISTCGSHLVVVSLFYGAIMLMYVSPTPGNSVAMHKLITLIYSVVTPVLNPLIYSLRNKDMKYALHHVFCGMRIIQRS
What is the function of this protein?
Odorant receptor.  Activated by isovaleric acid.
What are the official names of this protein?
Olfactory receptor 11H7, Olfactory receptor OR14-32.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSY_PSEPK
Sequence: MFWLLALLAYLLGSLSFAIVLSRLSGSPDPRSSGSGNAGATNMLRLAGRKLAILTLLGDLCKGLLPVLLARAAGLDLHAQAWVGICAVLGHLFPLYFRFKGGKGVATAAGMLMALYFPAALLAIGAWLLTFYLTRTSSLAALIATPLTLPLLAWREPEALLPISVLTVMIVWRHRNNLRDLFAGRERHF
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRD_NAUPA
Sequence: MSFFNMVKPLIYKTDPELAHDLVDLAMRTARRCPLFFNPLVKANFVDDVMLHQKIWDLEFKNPVGVAAGFDKHATMVYGWPALGFGWGEIGAVTPKPQPGNEKPRAWRHIEYEAVQNAYGFNNEGVEVIKKRLKKIYPFILPIGANIGKNKTTPEERAVEDYKILVNELKDVVDFFVVNVSSPNTPGLRDLLNAEFISSLFGELKNLTDKPILIKFSPDMEDELIINLANYSVLAGADGIIVTNTTVNYDLVNSEIKRGGISGKPLAQRSYEVLRIVAGEVFGKVPIISVGGIDSAEEAYKRIKAGASLLQVYTAIIYKGPGIVGEINRGLIELLKKDGYSHISEAIGVEIPKKLENKA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LUTA_BACSU
Sequence: MKVSLFVTCLVDMFQTNVGKATVELLERLGCEVDFPEGQICCGQPAYNSGYVHDAKKAMKRMIETFQDSEYVVSPSGSCTTMFREYPHLFQDDPKWADKAKKLADKTYELTDFIVNVLGVEDVGATLHTKATLHTSCHMTRLLGVRKEPMKLLSHVKGLQFTELPGKHNCCGFGGTFSVKMAQISEQMVDEKVECVEETGAEVLIGADCGCLMNIGGRLGRKDKNVKVMHIAEVLNSR
What is the function of this protein?
Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present.
What are the official names of this protein?
Lactate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.