PharMolix/UniProtQA huggingface dataset:
Protein: ISPH_ALISL
Sequence: MKIVLANPRGFCAGVDRAISIVERALELYKAPIYVRHEVVHNRFVVEGLKQRGAIFVEELSEVPDDNIVIFSAHGVSQAVRTEAKERALTVFDATCPLVTKVHMEVARASKKSIEVVLIGHAGHPEVEGTMGQYASEAGGMYLVETPEDVEKLIVQDPNNLHYVSQTTLSVDETADVIDELRRVFPKIQGPRKDDICYATQNRQDAVRDMAGQVDVMIVVGSKNSSNSNRLRELSEKLGTTSYLIDCPEELKEEWLTNQAKVGVTAGASAPEELVNQIIEQVKVFGGTTVDELKGREENMFFEVPKELQIKTVS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: LAMB_ECO27
Sequence: MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSGVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFATYAKWDEKWGYDYTGSSSTNPYYGKAVSADFNGGSFGRGDSDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GLUQ_GEOSL
Sequence: MCVPSTPQPPVIGRFAPSPTGPLHVGSLVAAVASYAMARRQGGLWLVRMEDLDTPRVVPGMADDILRTLECLGFDWDGDIMRQSRRADAYGAALQRLLAAGHAYPCGCSRAEIARAATAPHDGDGEIPYPNLCRRGLPPGKEPRSFRVRVPAEPVEFTDLVMGPQHHDLPAMCGDFVIKRADGLFAYQLAVVVDDEAQGVTQVVRGADLLSSTPRQIVLQRLLGFDTPVYAHVPLVTGPGGGKLSKRDNALSLAAGRDLTREGGMLLLAALRFLGQSPPAELAGASGARVLRWAAGNFEPSAIPTAAAPFHASP
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: RS18_CHLAA
Sequence: MSRSRASGRPRSRRRECEFTKLGIVPDYKDVKRLQKYLTAQGKILPRRRTGVSAKMQRRLAVAIKRARHLALLPVAPSHTR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ZN322_HUMAN
Sequence: MYTSEEKCNQRTQKRKIYNVCPRKGKKIFIHMHEIIQIDGHIYQCLECKQNFCENLALIMCERTHTGEKPYKCDMCEKTFVQSSDLTSHQRIHNYEKPYKCSKCEKSFWHHLALSGHQRTHAGKKFYTCDICGKNFGQSSDLLVHQRSHTGEKPYLCSECDKCFSRSTNLIRHRRTHTGEKPFKCLECEKAFSGKSDLISHQRTHTGERPYKCNKCEKSYRHRSAFIVHKRVHTGEKPYKCGACEKCFGQKSDLIVHQRVHTGEKPYKCLECMRSFTRSANLIRHQATHTHTFKCLEYEKSFNCSSDLIVHQRIHMEEKPHQWSACESGFLLGMDFVAQQKMRTQTEELHYKYTVCDKSFHQSSALLQHQTVHIGEKPFVCNVSEKGLELSPPHASEASQMS
What is the function of this protein?
Transcriptional activator (PubMed:15555580).  Important for maintenance of pluripotency in embryonic stem cells (By similarity).  Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes (By similarity).  Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly (By similarity).  Promotes inhibition of MAPK signaling during embryonic stem cell differentiation (By similarity).
What are the official names of this protein?
Zinc finger protein 322, Zinc finger protein 322A, Zinc finger protein 388, Zinc finger protein 489.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly found in the nucleus.
Protein: NANE_CUTAK
Sequence: MSGFTDRIIASMAGGLVVSCQAYPGEPLRHPETMAQMAAAVEAGGAVAVRAQGLSDVSAVKGRVSVPVVGIWKEGDEGIYITPTLRHARCVSAAGADVVALDGTRRERADGLSLAETIERLKREYDVVVMADCGSVDDGLFAAEAGADLIGTTLCGYTGERPKTDGPDYEVIEALVKKLDGDRPVIAEGRIHTPDQARRAMDLGAHAVVVGTAITHPTSITGWFRDALR
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: YQGE_ECO8A
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: UPPP_ALKOO
Sequence: MSIIELLKVIFLGIVEGITEWLPISSTGHMILVEEFIQLNASAAFKEMFFVVVQLGAIMAVVLLYFNKLNPFALSKTKREKRETMRIWYKVVVGIIPAGVMGLLFDDWLNEHLYNYWTVAAMLIVYGVLFIIIENRNKHRYAKINSFSELSYSTAFLIGLFQVLSLIPGTSRSGATIIGAIILGTSRYIAAEYSFFMSIPIMFGASAVKLLKFGFNFTSIEIITLVTGMVVAFVVSIIAIRLLMAYIKNNDFKAFGWYRIFLGVVVIGYFLITNGKVLS
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPF_PSEAB
Sequence: MRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGSIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: Y1226_ARCFU
Sequence: MVYEVLAVVSGGLLGFGVTWAYLNYALKEEKAKEEEVMRAKISNVTSSVEPKLETKMEKPPSDLSEFVDYLCNKYMLSDVTLLTPDGLPIASNSPTPEEDAAIAPELIKVGKGMLNSSRILLSGENTRVLVMQVNPDVLLHARVARDISKREIERIGEEVNMVLEGII
What are the official names of this protein?
Uncharacterized protein AF_1226.
Protein: DNAJ_PSEU2
Sequence: MAKRDYYEVLGVERGSSEADLKKAYRRLAMKHHPDRNPDDKASEELFKEANEAYEVLSDASKRAAYDQYGHAGVDPSMGGGGGFGGGAGGANFSDIFGDVFSDFFGGGRAGGGGGRGGAQRGSDLRYTLELNLEEAVRGTNVNIRVPTLVNCKPCDGSGAKKGSSPVTCPTCGGIGQVRMQQGFFSVQQTCPRCHGHGKIISDPCDSCHGEGRVEESKTLSVKVPPGVDTGDRIRLSGEGEAGTQGGPTGDLYVVINVREHAIFQRDGKHLFCEVPISFTDAALGGELEVPTLDGRVKLKIPEGTQTGKQFRLRGKGVAPVRGGGAGDLMCRVAVETPVNLSKRQRELLEEFRTSLENDESHSPKASGWFEGVKRFFGDL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRMD5_MOUSE
Sequence: MLSRLMSGSSRSLEREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLEKKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSSSHGDTFLPHVRSSRADSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEAEALGGELRALCQGHGGSEQEQRVHLKGPQLQQQQWKGWGKSVPLD
What is the function of this protein?
May be involved in regulation of cell migration.  May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1.  May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation.
What are the official names of this protein?
FERM domain-containing protein 5.
What are the subcellular locations of this protein?
Cell junction, adherens junction.
Protein: NUOK_SALPK
Sequence: MIPLTHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAA_HAEDU
Sequence: MNNIHNHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEKQIREFNPTGIILSGGPESTTETNSPHAPEYVFKAGVPVLGICYGMQTMAMQLGGLTEASEQREFGYAAVELQHADQLFAKLNDDLTASQPKLDVWMSHGDKVTRLPAGFQTTAVTPTCPIAAMSDEKRRFYGVQFHPEVTHTKSGLALLTNFVENICGCARSWTPENIIEDAVAKIKQKVGNDQVILGLSGGVDSSVTALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGDKFGLNIIRVNAEERFLEALKGIDEPEAKRKIIGKVFIDIFDDEAKKLTDVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLTLGLPAEMLNRHPFPGPGLGVRVLGEIKKEYCDLLRNADAIFIEELYKSGWYYKVSQAFTVFLPVKSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYELLGKISNRIINEVNGISRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: IMDH2_ARATH
Sequence: MSGFEDGFSAEKLFSQGYSYTYDDVIFLPHFIDFSTDAVSLSTRLSKRVPLSIPCVASPMDTVSESHMAAAMAALGGIGIVHYNCDIDTQASVIRHAKSLQVPIASDAVFKCPEHQIGSVDDFGPSSFVFVSQTGTLTPKLLGYVSKSEWSSMKDDQKEVKIYDYMKSCENKDYYVPWDIDLDKIEAVLEDKQKGFVVLEKEGETVNVVTKDDVERVKGYPKLGSGTVGADKKWMVGAAIGTRESDKERLEHLVKAGANVVVLDSSQGNSIYQLEMIKYVKNTYPELDVVGGNVVTMYQAENLIKAGVDGLRVGMGSGSICTTQEVCAVGRGQATAVYKVSTLAAQHGVPVIADGGISNSGHIVKALVLGASTVMMGSFLAGSTEAPGAYEYRNGRRVKKYRGMGSLEAMTKGSDQRYLGDTAKLKIAQGVVGAVADKGSVLKFIPYTMHAVKQGFQDLGASSLQSAHELLRDNTLRLEARTGAAQIEGGIHGLVSYEKKSF
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase 2, IMP dehydrogenase 2, IMPD 2, IMPDH 2.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_THEYD
Sequence: MEVIRIPRIMREISKELRFKGKSIGFIPTMGALHEGHLSLIRRAKEENDIVIVSIFVNPTQFAQGEDYEKYPRDVELDKEKLEALAIDYLFLPDVNSLYPEGYSTYVVVEGLSDKLCGIFRPGHFRGVATIVCKLFNIVKPLRAYFGQKDYQQSLIIRRMVEDLNFDVEIIVCPTVREQDGLAMSSRNLYLNEKERQSATVIYKALKEGERLLNEGEKPLDVKLKMHEIFKNEPLIREIQYAGVYDPLTLEEVKERQNKYLLAVALKIGDTRLIDNLIVE
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFRNP_METMP
Sequence: MQKQRFCLDTTAITDSDVRKSLGVSNISESAEKIMDIIAQARVQLDISCHIPYDTVYKELVGFLTREGCAPETLIKVDTWLVKKTPNRYEIKIPAEIFYEYIKDLRERINKGMRISENAMYETALEAYILSKPDEKDREDVLNEVLSKTVNSFRVKYRNALRGGTLDSAPDLDVLLLAKELDAAVVANDEGIEKWAQRLGLRFVNARDFPFILQEYLDLWDKK
What is the function of this protein?
RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.
What are the official names of this protein?
RNA-free ribonuclease P, RNA-free RNase P, Protein-only RNase P.
What is the protein family that this protein belongs to?
Belongs to the HARP family.
Protein: RS18_NITEC
Sequence: MANRPLFKRKKFCRFTAEGIKKIDYKDVDLLKDFISENGRIIPARITGTRSYYQRQLNLAIERARFLALLPYTDQH
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: YBDJ_LACLA
Sequence: MIERIKKFLRTKFKPLLLLLVTVILYNGWTPHLGIFPPTFYDFAFNYYGFVDILTFLVIIVIAYKNDAFKKIFDIFRPKNLLFILFFIVGGNIFIALAHHLYFQMTPALEAFPEHSIDLANYFARTPFWTHSLDLFVIGPISEELIYREYLYRLFDKKCLACFVSVTMFAWVHTGFTYSFFLYLPISLVVTLAYHRRKAIGESIALHSSINLINTYLPNLLSFWVF
What are the official names of this protein?
UPF0177 protein YbdJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0177 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS5_PHOLL
Sequence: MKVVILDTGCANLSSVTYAIRKLGYQPEISQETATILAADKLLLPGVGTASAAMDQLKQRELIPLIKVLSQPVLGICLGMQLFAATSEESDNVAGNNVTLLEVMASPVQKMATHGLPLPHMGWNQVLPKAGHPLFRGIEDHAYFYFVHSYAIPLNTYTIAQTEYGNIFSSAIAKDNFFGVQFHPERSGAAGARLLKNFLEM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_BORPD
Sequence: MLILTRRIGETIHIGDDITVTVLGINGQQVKFGTSAPREVDVHRQEIYERIHPGSASHFSGKHPY
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT2_PLEMO
Sequence: MNSPLRGIWLWLPLLLTWRAPEVSSSWWYMGATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAIGLGVTEWTSECQYQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSGKDSKGVFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKSVKRFLKQECKCHGVSGSCSLRTCWLAMADFRRTGDYLWRKYNGAIQVVMNQDGTGFTVANERFKKPTKNDLVYFENSPDYCIRDRETGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMIKCGCKFHWCCAVRCQDCLEALDVHTCKAPKNADWTTPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: OS9_RAT
Sequence: MAAEALLSSLLGLLFLGLLLPAHLTGGVGSLNLEELSEMRYGIQILPLPVMGGQSQASDVVVVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTYEFCYGRHIQQYHMEDSEIKGDVLYLGYYQSAFNWDDETAKASKQHRLKRYHSQTYGNGSKCDLNGKPREAEVRFLCDEGAGISGDYIDRVDEPFSCSYVLSIRTSRLCPHPLLRPPASAAPQAILCHPALQPDEYMAYLQRQAESKQHEEKVTEEVQDTDHQVWSGSKAAGAPPKKEDVSPTKEDKESEFWKMLQEPEEQATGTEEAQAGEQDLNHEAAADPAPAPPTDFQNNVQVKLIRSPADLIRLIEELKGAEKGKPSVRQEQPGDDTTEAPQREAEAKGKGGEPRGLVEEEDGDEEEEDEDEDEQQLLGEFEKELEGMLLPSDRERLRSEVKAGMERELENIIQETEKELDPEGLRKESEREQAILALTSTLDKLIKRLQESQSPELVQKYKKRRVVPQKPPPSPHPTEEEPEHRVRVRVTKLRHGGPNQDLTVLEMNRENPQLKQIEGLVTEVLEREGLTAEGKIEIKIVRPGAEGKEEDTRWLTDEDTRNLKEIFFNILVQGAEEANKERQRQSELESNYRRVWGSPGGEDTGDLDEFDF
What is the function of this protein?
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD).  May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation.  Possible targets include TRPV4 (By similarity).
What are the official names of this protein?
Protein OS-9.
What is the protein family that this protein belongs to?
Belongs to the OS-9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: GABD2_MYCTU
Sequence: MPAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKPLTTIPVGTAADVEAAFAEARAAQTDWAKRPVIERAAVIRRYRDLVIENREFLMDLLQAEAGKARWAAQEEIVDLIANANYYARVCVDLLKPRKAQPLLPGIGKTTVCYQPKGVVGVISPWNYPMTLTVSDSVPALVAGNAVVLKPDSQTPYCALACAELLYRAGLPRALYAIVPGPGSVVGTAITDNCDYLMFTGSSATGSRLAEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACFSNAGQLCISIERIYVEKDIAEEFTRKFGDAVRNMKLGTAYDFSVDMGSLISEAQLKTVSGHVDDATAKGAKVIAGGKARPDIGPLFYEPTVLTNVAPEMECAANETFGPVVSIYPVADVDEAVEKANDTDYGLNASVWAGSTAEGQRIAARLRSGTVNVDEGYAFAWGSLSAPMGGMGLSGVGRRHGPEGLLKYTESQTIATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate.  Although it has succinate semialdehyde dehydrogenase activity, is likely to act physiologically on a different aldehyde(s).  NAD(+) can substitute for NADP(+), but enzymatic activity is three times reduced.
What are the official names of this protein?
Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2, SSADH 2, SSDH 2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: RL23_SYNP6
Sequence: MAEANIRALADIIRRPIITEKATRLLENNQYTFEVDPRASKPEIKAAIEALFQVKVVGLSTQLPPRKARRVGRFAGHRAQVKRAVARLADGDSITLFPEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CMOB_NITSB
Sequence: MEIEEIKIEREGWLRWKNIAPLREKLSQMPKVECDVELGDVIKITGNIPRSLQEQVFETAWAMRPWRKGPFDVFGTYIDSEWKSFIKYNLLEPHFDLEGKDVADIGCNNGYYMFRMLTHHPRSLTGFDPSPLFRTQFDFINHFVQSSIVYELLGVEHVPRYGKKFDVIFCLGVLYHRSDPIAMLKWLKQGLKEGGEIFLDTFYIEGEDPVALCPGKTYSKIPNVHFVPTIKALQNWCQKAGFEYFEILATKPTTFEEQRKTEWILGESLENFLDPADPKRTVEGYPAPQRVYVRLRRKR
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: TF2B_PYRWO
Sequence: MNKQKVCPACESAELIYDPERGEIVCAKCGYVIEENIIDMGPEWRAFDASQRERRSRTGAPESILLHDKGLSTEIGIDRSLSGLMREKMYRLRKWQSRLRVSDAAERNLAFALSELDRITAQLKLPRHVEEEAARLYREAVRKGLIRGRSIESVMAACVYAACRLLKVPRTLDEIADIARVDKKEIGRSYRFIARNLNLTPKKLFVKPTDYVNKFADELGLSEKVRRRAIEILDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQREVAEVARVTEVTVRNRYKELVEKLKIKVPIA
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: ATPD_HAMD5
Sequence: MSMATIARPYAKAIFDFAVEHHSIEHWQNMLAFSAQVSAHKQVTQWLSGVMHSEKTAQIFISLCSDHLDEFSKNFIKIMAQNGRLSLLPEVLKQFMALRAMINSVIDIEVFSAIPLNEDQKKKIIFALEKRLQLKVTLNCKIDESILAGVIIRHGDRVIDGSVSNRLKRLKNFLLS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FOLD_MYCSK
Sequence: MSGVGAITLDGKATRDEIFVDLKERVAALTEQGRTPGLGTVLVGDDPGSQAYVRGKHSDCAKVGINSIRRDLPADISQAELDATIDELNANPECTGYIVQLPLPKHLDENAALERIDPGKDADGLHPTNLGRLVLNEPAPLPCTPRGIVHLLRRYEVEIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCHTATRHLPQFTREADIIVAAAGVPHMVTAEMVRPGAAVIDVGVSRDDNGKLVGDVAPDVWEVAGHVSPNPGGVGPLTRAFLLTNVVERAEALARG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MURA_CHLTE
Sequence: MDKLVIRGGKQICGTIPASGSKNSALPIIAATLLTPDGTFAIDRTPDLKDVRTFIQLLNYLGAETSFENNLLKVSTGQLKSIEAPYELVKKMRASIYVLGPLLARFGHTRVSLPGGCAFGPRPVDLHIMVMEKLGATVTIEKGFINARVNGSRLRGTHIDFPISSVGATGNALMASVMAKGTTILDNAALEPEIECLCNFLVKMGAKIDGIGTTTLVIDGVDQLKAVEFENIFDRIEAGTLLCAAAITGGSVTVTSVAPEQLASVLDAFRQSGCTVTTNGNSVTLTAPAELNPVDITARPYPEFPTDMQAQWMALMTQARGDSTIIDRIYLERFNHIPELNRLGAHIEIRDNWALVHGPQELTGTKVMSTDLRASACLVLAGLVAKDTTEVLRVYHLDRGYEAIEKKLTALGADIRREKYQEFS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.