PharMolix/UniProtQA huggingface dataset:
Protein: ASSY_WOLSU
Sequence: MSKKINKIVLAYSGGLDTSVILKWLQEQYQCEVVTFTADIGQGEEVEPARAKAKLLGIKEENIFIKDLKEEFVRDYVFPMFRANTLYEGEYLLGTSIARPLIAKHLVEIAKEVGADAISHGATGKGNDQVRFELGGYALMPDVKVVAPWREWDLNSREKLLAYAEKHGIPIEKKGKKSPYSMDANLLHISYEGGILEDPASEPEEDMWRWSVSPLDAPDAPERITIEFERGDAVGINGVKMSPATLLAELNRLGGKHGIGRLDLVENRYVGMKSRGCYETPGGTILLKAHRAIESLTLDREETHLKDEMMPRYASLIYNGYWFSPERRALQALIDETQKNVTGSVGLKLYKGNVILAGRTSERSLFNTAYSTFEEDSVYNQKDAEGFIKLNALRFIIAGKANPS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBB1_PSEE4
Sequence: MNELTSRLNRERRFLVLLGVICLALIGGALYMQVVLGEAPCPLCILQRYALLFIAIFAFIAAAMPGRKSLTFFEVLVVLSAIGGIVAAGNHVYILANPMVSCGIDTLQPIVDDLPLAKLWPLAFQVDGFCSTPYPPILGLSLAQWALVAFVLTTVLVPLGIYRNRRRG
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B 1, Disulfide oxidoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL2_PARUW
Sequence: MFKKYRPVTPGTRQLALPTNEQLTRPCENSRATVKPTKSLLLPKRRTNGRNNNGHITCRHKGGGHKQHYRIVDFKRDKENIPAKVASIEYDPNRTAYIALLNYADGEKRYILAPQGLKAGDKVQTSDEPPFHIGCCMKLRLMPLGSVIHNIELYPGKGGKLVRSAGLSAQLMARSGGYATIRMPSGEVRMINENCRATFGAVSNPERNLRVEGKAGRMRWKGIRPTVRGTAMNPVDHPHGGGEGKHKGNTPQTPWGLYTKGLVTRSNKKSNKLIVKRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CAV1_PIG
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMAEEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINMQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: GLYA_STAAC
Sequence: MSYITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFVDVTESIAIDRAKALFGAEHVNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHLTHGAPVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMILCKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKDEEKLQQAKERVAKLTAEYPLYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1978_BORBR
Sequence: MLIQIADLFTPAEAAQIRARLEAADWVDGKVTAGYQSAQVKHNRQLSEQHPLAQELGGLILQRLAANNLFMSAALPRKIFPPLFNRYEGGEAFGYHVDNALRPVPGTAERVRTDLSATLFFSEPDSYDGGELVVDDTYGPRTVKLPAGHMVLYPGTSLHKVTPVTRGARISAFFWLQSLVREDSQRSLLLEMDVAIQRLNQDTPGHASIVQLTGVYHNLLRRWTDV
What are the official names of this protein?
PKHD-type hydroxylase BB1978.
Protein: MODD_PASMU
Sequence: MLYFSDNELDDFLLEDIYRGDLTTHALGLESIPAEICFKRKNAGIVAGISIAEKLLRKLDIHPQVYVKEGEFVEAGSLLLSAKGSADKLHQAWKVVQLVLEWSCGVAQYTAEMISNAKAINPAAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGLSETLLVFTNHRNLLSDPEDWQGIVTRLKQQAPENKITLEADNLVQFEQMLTADPDIIQLDKFTLEQVKQALHLLALANKNITLSVAGGVNKHNVAEYAKLGIQLFITSAPYYAAPEDIKVIIEKQV
What are the official names of this protein?
Putative pyrophosphorylase ModD.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: LEUC_SHEAM
Sequence: MAKTLYEKVWDAHLVVEPAGEAPIIYVDRHLVHEVTSPQAFSGLKMAGRPLRAVEKTFATMDHNTSTKSASLTALSPMARTQVETLADNCRDFNVRLYDIHHPNQGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLRQLKAKTMKIEVRGKVADGITAKDIVLAIIGKIGMDGGTGYVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGMVAPDETTFAYLEGREFAPKGDAWQQALADWRELHTDADAVFDAEVVLEAAAIAPQLTWGTNPGQVVAIDGVVPNPADETNPVVRTSMEKALAYVDLTPGTPMTDIAINKVFIGSCTNSRIEDLRAAAAQAKGRKVASGVTAIVVPGSGQVKLQAEAEGLDKIFLEAGFEWRLPGCSMCLAMNDDRLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAVAGHFVDIRVHRPLED
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: GGYF1_MOUSE
Sequence: MAAETLNFGPEWLRALSSGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLPATSRGRGSTRSRGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQSWDDRGERRFEKPARRDGVRSGFEEGGAGPRKEHARSDSENWRSLREEQEDDGSWRLGAGPRRDGDRWRSTSPDGGPRSAGWREHGERRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRGLDGFEDDKDGLPEWCLEDEDEEMGTFDASGAFLPLKKGPKEAIPEEQELDFRGLEEEEEEEEEPSEGVDEERPEAGGKEATPLPPPENSSSPSSLPALGPLWTTNEEGGEAVEKELPPAEGDELRGLSLSPRISSPPGPPGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSTAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQHFLQLVGSRQLPQCTTLREKAAMGDLTPPQQQQLTTFLQQLQALKTPRGGDQNLLPTMSRSLSVPDSGPLWDLHTSASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRREEKRRQQQQQQEEQKRRQEEEELFRRKQVRQQELLLKLLQQQQATNVPVPPAPSSPPPLWAGLAKQGLSMKTLLELQMESERQLHKQAAPREPLRAQAPNHRVQLGGLGSAPLNQWVSEAGPLWGGPDKSGGSSGGNLGLWEDTLKSGGSLARSLGLKSSRSSPSLSDSYSHLSGRPVRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTAGSLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQQQQQQQQQEAWLSSTSLQTAFQANHSTKLGPGEGSKAKRRALMLHSDPSILGYSLHGPSGEIESVDDY
What is the function of this protein?
May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling.  May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1.
What are the official names of this protein?
GRB10-interacting GYF protein 1, PERQ amino acid-rich with GYF domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the GIGYF family.
Protein: PURL_LACLS
Sequence: MTLEMLPEQIQESKIYREWGLTDEEYLKIKDEILGGRLPNFTETGMYAVMWSEHCCYKNSKPVLKKFPTTGPQVLMGPGEGAGVVDIGDDLAVVFKAESHNHPSYVEPYEGAATGSGGIIRDIFSMGARPIAILDSLRFGPIDNGKTRHIVDQVTAGIAGYGNCIGIPTVGGEVAFDESYAGNPLVNVMCVGLIEHKHIQKGQAKGVGNSIFYVGAKTGRDGIHGASFASKEFGSGSETQRSAVQVGDPFMEKLLLEACIEVIQNHGDILVGIQDMGAAGLVSSTSEMASKAGSGLRLNLDNVPQRETEMIPYEMMLSESQERMVLCVKKGHEQEIIDLFKKYDLDAVNIGEVTDDGFYTLYHKGQMVAHVPVDSLAEDAPTYYREAKVPERIQKFTDSEKYLPEITDSAVSEIFKKLLAQPTIASKKSIYETYDSRVMTNTVVAPGSDAAVLRVRGTNKALAMTTDCNARYLYLDPEKGGAIAVAEAARNIVASGGKPLAITDCLNFGNPEKPEQFWELTTAADGISRSCLALDTPVISGNVSLYNETNGSAILPTPMIGMVGLIEDVKNITTQEFKKAGDLIVLVGQTFDDFSGSELQKMLTGEISGKIDFDLETEKVNQDFVLKAITDGLINSAHDLSEGGLAIALAESAFANGLGIDVEVDLSNAQLFSETQGRFVLSISPENQAAFEKLLTESSASSEVIGKVTDNGILKINELSISTDEAVSIYEGALPCLMK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_SALTI
Sequence: MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESKESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGRDAFIDKIWQWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETVLGDTGVAVNPEDPRYKDLIGKFVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAEVFDTKGEESNVYSSEIPAEFQKLERFAARKAIVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDNDGNVYVGRTEDEVRQENNLGADVQLRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQMAEKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEEQDCGFNGGEMTLSLADRWILAEFNQTVKAYREALDNFRFDIAAGILYEFTWNQFCDWYLELTKPVMTGGSESELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVICGITADTIMLQPFPEYNAAQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSEEAVRRVNDNRSFLLNLARLESITVLPADDKGPVSMTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEIARIEGKLSNEGFVARAPEAVIAKEREKLDGYAEAKAKLIEQQAVISAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERFB_YEAST
Sequence: MALVSRRSTRSESTSITKEEHTGEGSLTKLFFRWLVTLEGDQDINDGKGYISLPNVSNYIFFLGGRFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHTQNGYKVLVIFFYYFWVITLASFIRTATSDPGVLPRNIHLSQLRNNYQIPQEYYNLITLPTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFFLIFLLGAILSSVILLTNCAIHIARESGGPRDCPVAILLLCYAGLTLWYPAILFTYHIFMAGNQQTTREFLKGIGSKKNPVFHRVVKEENIYNKGSFLKNMGHLMLEPRGPSFVSARKPHEAGDWRFMDLSPAHSFEKIQKI
What is the function of this protein?
The ERF2-SHR5 complex is a palmitoyltransferase specific for Ras proteins.  Palmitoylates RAS2, which is required for its proper plasma membrane localization.
What are the official names of this protein?
Palmitoyltransferase ERF2, DHHC cysteine-rich domain-containing protein ERF2, Ras protein acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Protein: NHAA1_PSEU2
Sequence: MTQVPNRETPRGIAILARFLASESAGGIVLMVAALAALIVANSPLSAGYFSILHSVWLGLSVELWINDGLMAIFFLMVGLEIKREVLAGGLASWGQRALPGFAAAGGMLVPALIYIAINWGNPQTLSGWAIPAATDIAFALGVLSLLGNRVPTSLKVFLAALAILDDLGAVTIIAFFYSAGLNLPMLAAAFVTLAVLIVMNRLNVRRLLPYLLLGALLWFFVLQSGVHATLAGVALALCIPMGKPEEEARSPLLFLEEKMHYWVAFAVVPIFGFANAGVSLAGITLGNLVDPVPLGVALGLFVGKQIGVFLAAVLAIRAGLAVLPEGSNWVQLYGVAMLCGIGFTMSLFIGNLAFPGSQHLIDEVKVGVLIGSGLAAIAGIVLLRSRFSRP
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YFEW_SALG2
Sequence: MKFTLVATVLLTFSLSAFAVEYPVLTIASPDQVGFDSQKLHRLDGWIQNQIDAGYPSINLLVIKDNHIVLQKAWGYAKKYDGSTLLAHPIRATTNTMYDLASNTKMYATNFALQKLVYEGKIDVNDLVSKYIPGFKDMPGDKIKGKDKLRIIDILHHVAGFPADPQYPNKNVAGKLFSQSKSTTLEMIKKTPLEYQPRSKHIYSDVDYMILGFIIESITAMPLDRYVETTIYKPLGLKHTVFNPLMKGFTPPQIAATELHGNTRDGVIHFPNIRTNTLWGQVHDEKAWYSMGGVSGHAGLFSDTHDMAVLMQVMLNGGGYGNLKLFDDKTVAQFTRRSPEDATFGLGWRVNGNSSMTPTFGVLASPQTYGHTGWTGTLTSIDPVNHMAIVILGNRPHSPVANPKVNPNVFVSGLLPAATYGWIVDQIYGSLK
What are the official names of this protein?
Putative D-alanyl-D-alanine carboxypeptidase, DD-carboxypeptidase, DD-CPase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family. YfeW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL18_TROW8
Sequence: MSLTSRASARKRRHVRLRKKISGTCDRPRLSVTRSNRHVFVQAVDDISGKTLVSASTMEKDIRALELGKTERALAVGKLVAQRALAVGVKSAVFDRGGCKYTGRVAAVAEGAREAGLQT
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PSME1_HUMAN
Sequence: MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY
What is the function of this protein?
Implicated in immunoproteasome assembly and required for efficient antigen processing.  The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
What are the official names of this protein?
Proteasome activator complex subunit 1, 11S regulator complex subunit alpha, REG-alpha, Activator of multicatalytic protease subunit 1, Interferon gamma up-regulated I-5111 protein, IGUP I-5111, Proteasome activator 28 subunit alpha, PA28a, PA28alpha.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
Protein: DYR_ENTFC
Sequence: MFISMWAQDKNGLIGKDGLLPWRLPNDMRFFREHTMDKILVMGRKTYEGMGKLSLPYRHIIVLTTQKDFKVEKNAEVLHSIDELLAYAKDIPEDIYVSGGSRIFQALLPETKIIWRTLIDAEFEGDTFIGEIDFTSFELVEEHEGIVNQENQYPHRFQKWQKMSKVV
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: AAEX_YERPY
Sequence: MSLLPVMVIFGLSFPPIFLELLISLALFFVVRRILQPTGIYEFVWHPALFNTALYCCLFYLTSRLFS
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAF20_DEBHA
Sequence: MAKYTEEQLYEIKEEAYTPQPDVLDAFNKMVDHVKEHAAAEFEKHKNLKWSNGDTYIDENGNERPYHHMNKRRGSRSGNKPNLRKKSTDGIKVDDDGWATLTKPKKSFGAEDGVEERNKFRESVKDIKVKPNNKNLGSSKAVDPRDAIAEKHTNTFNAFEALGDGDDSDDE
What is the function of this protein?
Acts as an inhibitor of cap-dependent translation.  Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA (By similarity).
What are the official names of this protein?
Cap-associated protein CAF20.
What is the protein family that this protein belongs to?
Belongs to the CAF20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAR1_VANPO
Sequence: MSALLREEDLNDFITPEVACIKPVSSKPSNGVDGELSVGKEPEKVEISLADCLACVGCITSSEEILLSRQNQDVFVKEWNEKKTEGYILSVSIAPQCRVSLSQYFGMGVLKFDQMFIRYLQEVWGARYVVGIQEGREESIKLMNEVADKGERKICSACPGFLMYCEKKQQDLLPLLIDVKSPMEITGHLLKDGNKEKMYHLSIMPCFDKKLESMRPESIGLVDCVITPKELVNLITPEQVDKYFATTKETIGMLEWEDAIQRVTPKWMNIDTSFKTNEGSSSGGFAWQYILHRRFQMSDNDNDNAYKIETVRGRNLDVTEFRLIDEEGKILVRSTQVFGFRNIQNLRRLVKDVKPRKLKRFIRKRPTANGNDNSISLSSSINNQDNNNTKVEEPVDFCKSDFLEVMACPRGCIAGGGNLKNGIKNGPDQDSDPNQDLNTVYMTSIPMTSIEPRHNLTLPSSQENVIVGVISHDLDDSNTIIKLQEEQKYGNKYKRKLYNPSSISETHNGDSKNTIEQPVQFTTW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: PYRR_SYNJA
Sequence: MSTVEVFNAQQIAELIDALATAIARDHPHLDRLVLIGIRTRGVPLAYRLRDRIATGFGSPPQVGELDITFFRDDLGSGGLRTPNRSELPRDLTGQEVVLVDDVLFRGRTVRAALEALNHFGRPEQVRLAVLIDRGHRQFPIQPDYCGHKLTTAPEQIVKVHLRETDGEERVLLIDAKLEENSRE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: FABZ_CALBD
Sequence: MYNIDKILEIIPHRYPFLLVDRIIEVEEGKRAKGIKNVTINEPFFQGHFPSNPVMPGVLIVEAMAQVGAVAMLLKEEFKGKTPFFAGIDKVRFKKVVKPGDVLVIETELISLKGSIGKAKAVAMVDGEVVCEGELLFAIK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMCL1_MOUSE
Sequence: MGALSSRVLRPAGRTEQPEPTPGAGGAARRSDAGEDAGHSFCYCPGGRKRKRSSGTFCYCHPDSETDDDEDEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWSLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDIEALQVAFGSLYRDDVLIKPSRVVAILAAACMLQLDGLIQQCGETMKETISVRTVCGYYTSAGTYGLDSVKKKCLEWLLNNLMTHQSVELFKELSINVMKQLIGSSNLFVMQVEMDVYTALKKWMFLQLVPSWNGSLKQLLTETDVWFSKWKKDFEGTTFLETEQGKPFAPVFRHLRLQYIISDLASARIIEQDSLVPSEWLAAVYKQQWLAMLRAEQDSEVGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDLLVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRATGYQILTLEKDQEQVVMNLDSRLLIFPLYICCNFLYISPEKRTESNRHPENPGH
What is the function of this protein?
Possible function in spermatogenesis.  Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport.
What are the official names of this protein?
Germ cell-less protein-like 1, mGcl-1, DP-interacting protein, DIP.
What are the subcellular locations of this protein?
Nucleus matrix.
Protein: ACCD_DIOEL
Sequence: MEKWWWFNSILSNERLEHRYGLSKSMDSVNGIEYTKDPILNDTEKNILGWSDSSNYSFSTVDYLFEIRNIWSLISDDTFLVRDSNGDSYSVYFDIENQIFEIDNNSSFLGELESFFSSYLNRGSKNKYYHYMYDTQFSWNNHITNCIDSYLRFEIGISITSYISGDIVNYSDGYIYSFICTESVSSNESGSSSIRTSSNGSDFNMRENSNDSDINKKYRHLWVQCENCYGLNYKKFFRSKMNICEQCGYHLKMSSSDRIEVSIDPDTWDPMDEDMVSIDPIEFHSEEEPYRDRIDSYQRKTGLTEAIQTGIGQLNGIPIAIGVMDFQFMGGSMGSVVGEKITRLIEYATNESLPVIIVCASGGARMQEGSLSLMQMAKISSASYNYQSNKKLFYVSILTSPTTGGVTASFGMLGDVIIAEPNAYIAFAGKRVIEQTLNKTVPDGSQSAEYLFHKGLFDPIVPRNPLKGVLSELFQLHGFLPLNQNKKEN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PK4_DICDI
Sequence: QQQQQQQQQQQQQQQQQHQKTSPSTSFVDYNNINNSNGNNINGTTSTCNSTSSSKSNSKEIYNENNNNNNNNNNNSFTNVHNNNNNNNNNRKRRNSHISYDTPDSNNIDNNIESNDTESGFRKNSKKSTDNNNNNNNNNNNNNNNNNNNNNNNNNNNSCNINGNINNGNSNNINNNNCSNIDSTLADVSKHQYTNQHQQQQNIQQQQQQQQQKNQQQQQQQQQQQQQNNQQQQQNNQQQQQNNQQQQQHQQQNSQQQQNNQHQQQLQQQQYQQKHYNNNNNNNNNNQPQTSNQNIQHSQGLNYNQNQNQNQNQEAPIVVNSLILRSIGMMTSKISKDFEELTTFMKSSCPMLLRFSGVENSYHILEKLNNIITQSLEGLPKTPQCSQPPFNQLIPLSNTTTLTPNNYNNNNNNSNNNNNSNNNNNNNSNNNNSNNNNSNNSNNNNNNSNNNNSNNNNSNNNNSNNNNNNSNNNNSNNNNSSNNNNNYSGFNDQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQKHQQTQHSQQHQQQYQQHIQQNNQYQQNQNITQSSQIPQFKSNNIQSLIHNNQQHYTQNNLVNNNNNTNNNNNNNNYNNKTYYQPSVHENQYMASAIAPIHNHQSSPNPFYQQKLTIPQQTNNQSTRISAQFIIQNINNQQIQGTYINFNSCKLSDFKLFDLLGSGSFAKVRLCQHIPSERLFCMKILNQNKIIRLRQEVHVCNEKQVLMLTDNPFIVKLYSTFKDDRYLYFLQEFIPGGELFDYIRANGSLSLYVTQIYAAEIVLALEYLHNQDIIYRDLKPENLLIDQYGHIKLTDFGFAKRITENTKSMCGTPEYIAPEILSGHGHGKSADWWSLGILIYEMLVGVPPFVSEGSQNDIFRLIREARIQVPPEVDQVARDLIEKLVVTDVEKRLGSLEGGIEDIKNHPFFGAINWNSIQNRESAPLKPRIRPLKHHLMDERDEEDRISANFIKPDLLERRKNEFFSNF
What are the official names of this protein?
Protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Protein: RL22_CHLCV
Sequence: MFKATARYIRVQPRKARLAAGLMRNLSVMEAQQQLNFSQLKAGRCLKKVLDSAVANAVLNENVKREQLSVIEVRVDAGPVYKRAKSKSRGGRSPILKRTSHLTVIVGEKER
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: FLIQ_ECO57
Sequence: MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG
What is the function of this protein?
Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis.
What are the official names of this protein?
Flagellar biosynthetic protein FliQ.
What is the protein family that this protein belongs to?
Belongs to the FliQ/MopD/SpaQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Bacterial flagellum basal body.