PharMolix/UniProtQA huggingface dataset:
Protein: RL1_NAUPA
Sequence: MAKKHSKRYQELLKKIDKDVYNLKEAAEKVKELKSAKFDETVELALKLGVDPRHADQMIRGSVVLPHGTGKTVKVAVLAKGAKADEAKEAGADIVGEEEVLEMIQNGNLDFDILIATPDMMGKLGRFGKILGPKGLMPNPKTGTVTMDVAQAVKNAKAGQVNFRVDKKGNMHVGIGKASFDAEKIYENAVAFIEKINKMKPASAKGRYIQNAALSLTMSPSVKLDVNELTEYK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TRMB_TREPS
Sequence: MTNDSARMRKVLTFTRRSNRMTACQKRDYQHLASRWIIPYQNTVFDYAAVFCSPAAPSAPAGAFPAPQGKTDAVAPACAPAPLVVEIGFGMGSATAAIAARNPHLSYLGIEVYRAGIGRLLRKIEAERLHNLRIIEHDALDVLRTMIAPQTLAGLHIFFPDPWPKTRHHKRRLLYRPRTDLLARALAPGGYLYAVTDWAEYARRAQEELARTPSLTWAPQGARPWRPATEFERKAQTQGRAIHELFFIKA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RNH2_BURPS
Sequence: MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVVHALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDRMLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCFS2_YEAST
Sequence: MSEVSKWPAINPFHWGYNGTVSHIVGENGSIKLHLKDNKEQVDFDEFANKYVPTLKNGAQFKLSPYLFTGILQTLYLGAADFSKKFPVFYGREIVKFSDGGVCTADWLIDSWKKDYEFDQSTTSFDKKKFDKDEKATHPEGWPRLQPRTRYLKDNELEELREVDLPLVVILHGLAGGSHEPIIRSLAENLSRSGRFQVVVLNTRGCARSKITTRNLFTAYHTMDIREFLQREKQRHPDRKLYAVGCSFGATMLANYLGEEGDKSPLSAAATLCNPWDLLLSAIRMSQDWWSRTLFSKNIAQFLTRTVQVNMGELGVPNGSLPDHPPTVKNPSFYMFTPENLIKAKSFKSTREFDEVYTAPALGFPNAMEYYKAASSINRVDTIRVPTLVINSRDDPVVGPDQPYSIVEKNPRILYCRTDLGGHLAYLDKDNNSWATKAIAEFFTKFDELVV
What is the function of this protein?
Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity).  MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification.
What are the official names of this protein?
Medium-chain fatty acid ethyl ester synthase/esterase 2, Alcohol O-acetyltransferase, Ethanol hexanoyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
Protein: ZN331_HUMAN
Sequence: MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLDLESAYENKSLPTEKNIHEIRASKRNSDRRSKSLGRNWICEGTLERPQRSRGRYVNQMIINYVKRPATREGTPPRTHQRHHKENSFECKDCGKAFSRGYQLSQHQKIHTGEKPYECKECKKAFRWGNQLTQHQKIHTGEKPYECKDCGKAFRWGSSLVIHKRIHTGEKPYECKDCGKAFRRGDELTQHQRFHTGEKDYECKDCGKTFSRVYKLIQHKRIHSGEKPYECKDCGKAFICGSSLIQHKRIHTGEKPYECQECGKAFTRVNYLTQHQKIHTGEKPHECKECGKAFRWGSSLVKHERIHTGEKPYKCTECGKAFNCGYHLTQHERIHTGETPYKCKECGKAFIYGSSLVKHERIHTGVKPYGCTECGKSFSHGHQLTQHQKTHSGAKSYECKECGKACNHLNHLREHQRIHNS
What is the function of this protein?
May be involved in transcriptional regulation.  May play a role in spermatogenesis.
What are the official names of this protein?
Zinc finger protein 331, C2H2-like zinc finger protein rearranged in thyroid adenomas, Zinc finger protein 361, Zinc finger protein 463.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1196_ARATH
Sequence: MDWTMISGSRDESLHAARDYWRRLNESECFDIEGIEAPPGAIALIPYDCQLPNSFHPLPLWVKLYASAGLHRFNMLEVLVNERSVGKLNIIVPIARPKGVTTNERFIPCDCFSVDDKLPQWPSHDSFNDRKRFYSVKESELQNNDWINLYLELVLCAIQKVRISDSDLSKLKIVKAVIETKEDMVPPNERLNAKTAVVYITFKGLANARIAAGEHYERKAIIRRIFNEHTGHLSLLGDLIGEKKFVNIDPVTYFNSPAYLEDITHELPPESPWMDILAGTGSMDQID
What are the official names of this protein?
UPF0725 protein At1g19060.
What is the protein family that this protein belongs to?
Belongs to the UPF0725 (EMB2204) family.
Protein: SYM_CHLT2
Sequence: MESSRILITSALPYANGPLHFGHITGAYLPADVYARFQRLQGKEVLYICGSDEYGIAITLNAELAGMGYQEYVDMYHKLHKDTFKKLGISVDFFSRTTNAYHPAIVQDFYRNLQERGLVENQVTEQLYSEEEGKFLADRYVVGTCPKCGFDRARGDECQQCGADYEARDLKEPRSKLTGAALSLRDTEHAYLHLERMKEDLLAFVQGIYLRPHMRNFVTDYIEHLRPRAVTRDLSWGIPVPDLENKVFYVWFDAPIGYISGTMDWAASIGDPEAWKKFWLDDTVTYAQFIGKDNTSFHAVIFPAMEIGQSLPYKKVDALVTSEFLLLEGFQFSKSDGNFIDMDAFLETYSLDKLRYVLAAIAPETSDSEFSFQEFKTRCNSELVGKYGNFVNRVLAFAVKNGCTELSSPQLEQKDLDFISKSQKLAKDAAEHYAQYSLRKACSTIMELAALGNGYFNDEAPWKLAKEGNWNRVRAILFCACYCQKLLALISYPIMPETALKILEMIAPYSLDLGSQDPDRLHSLWTDSFFDYSEEKFSLKEPELLFTMVE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1989_PYRHO
Sequence: MKKYLLIIIGVTLVLILLWWAGIERTIKLMMRADIRFILLAILMYCISVLIWAVRWNTFLKGANINVSFVKVIEGVFIGIFLNNLTPGARTGGEAVKVIFIKKASSNGSYSKVFATVIADRILDVIPVVVFMMLAFLYALTIHARVLLIILGISAIILVIILLMTTVFSIKEKYALSALLYLARIFRKIFPSKFSMSEDKIKEKLLGEIREFKETFLRLAKRKRRLSSTMLYSFILWGADILKTYFIFLSLGGRITFLQVLLVRMASIAVAMISVIPGGIGITEVVQSALFLAVGVEKALAVSVTMLDRLISFWIPTLLGGILVLKNRKLLVSSS
What are the official names of this protein?
UPF0104 membrane protein PH1989.
What is the protein family that this protein belongs to?
Belongs to the UPF0104 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEOC_SHESR
Sequence: MTDLKKAAQRAIELMDLTTLNDDDTDQKVIDLCHKAVTPAGNTAAICIYPRFIPIARKTLDELGAEDIQIATVTNFPHGNDDIAIAVLETRAAVAYGADEVDVVFPYRALMEGNETVGYELVKACKEACGEVLLKVIIESGVLADPALIRRASELSIDAGADFIKTSTGKVPVNATLEAAEIMLTVISEKNTKVGFKPAGGVRDAAQAAEFLGVAERILGADWVSPRTFRFGASSLLNSLLHTLELADAPKPTQGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCEH_BLAVI
Sequence: MYHGALAQHLDIAQLVWYAQWLVIWTVVLLYLRREDRREGYPLVEPLGLVKLAPEDGQVYELPYPKTFVLPHGGTVTVPRRRPETRELKLAQTDGFEGAPLQPTGNPLVDAVGPASYAERAEVVDATVDGKAKIVPLRVATDFSIAEGDVDPRGLPVVAADGVEAGTVTDLWVDRSEHYFRYLELSVAGSARTALIPLGFCDVKKDKIVVTSILSEQFANVPRLQSRDQITLREEDKVSAYYAGGLLYATPERAESLL
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein H chain, Photosynthetic reaction center H subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PuhA family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Single-pass membrane protein.
Protein: PYRB_AZOPC
Sequence: MKKKDFVSITDCSKQDILHLIERSAYFERNLNQLLLKDKICATLFFEPSTRTRLSFETAINRLNGRIIGFSDVHTTSSSKGETLKDTIKIVSNYADVIIMRHYLEGAARYASKITDVPIVNAGDGANQHPSQTLLDIYSMYKTQGTLYNLTITIVGDLKYGRTVHSLLNGMSYFNPTFHFIAPEELKLPIIYKQFMDENSIQYFDHSDFLVDIINQSDILYMTRVQRERFNDLIEYEKVKNVYVLSNDMLADSKDNLRILHPLPRVGEITSDVDTNPKAYYFEQARNGIFARQAIICDVLGL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: NFUA_XANC5
Sequence: MIQISDKAQTYFRKLIEREGVPGMGVRLSAVDAGTPRADARLEFAEPADLSGDEWAIDCDGFTLYVVAASVPWMDGAEIDYVTQSTGNQQLTIKAPKIKGEAPAESASMVERVRWVVENEINPQLASHGGRVAVQEVSADGVVLLRFGGGCHGCGMADVTLKQGIEKTLMGRVPGVTAVRDATDHATGDAPYIPRDSAA
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: AROQ_HELPJ
Sequence: MKILVIQGPNLNMLGHRDPRLYGMVTLDQIHEIMQTFVKQGNLDVELEFFQTNFEGEIIDKIQESVGSDYEGIIINPGAFSHTSIAIADAIMLAGKPVIEVHLTNIQAREEFRKNSYTGAACGGVIMGFGPLGYNMALMAMVNILAEMKAFQEAQKNNPNNPNNPINNQK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: GYF1_CAEEL
Sequence: MSSVSSAEPTAQQNFNPSCHFRMRPNAANRGGSISSGNNRSSGFGGGGFDDGGDEISSSAIAAAAAAVLSSPVVSEFSYTRERLLELAPTGSIMPDALRDQLFFNEKNLPLVSNTPLSEHEQKLQHNINSSKAMSLLSHADRASIAAGAAYGSGYGAASGALQNGQSPTSRWAPKSSWNKGTPDRGTGTTPRGGGSVGRASGAFFAGRGGGRIGGENGFGGATNGGSPAAQNEDSPGTYQSKFNALRRGGGAGSVGRGGSTTGSAFNTRADALYNPNDPTDRPKAVNPAATRSESDEEEEEGWSKVGSTSRTSTNAAPQSSERPAWARSESWIQRTQQQQQQQQQQSTQQQAQPPITLWNNREVGSDSTVWKDRNHMVAAVRKASTENHPPQQQQQQQQRSSAPVSAPSRQESESTDVPNLPIPTYPSDPSAWSNNSMGGGIFYQPTPQPPAPIVKEEPVQFYYMDPTETRRGPFPKDQMNVWFKAGYFTDESLRVQRGENGEYKTIGDLKKLHGSSTPFEYLEDIEPPRPILPSIPYPSATNPLYPAAFGGVNMWSSMGQPTDVYMMQTNFEQQLVAERNRLLDDHNRRLAEEAEKMAKFQEAMYRQLTMQHEQRVREQELLLQKRAEEIEKREAESKREEAARLQKLEQEAREIEERKAALEAEDRRKREIEEYNRMCEKKKNEIIAKEAADRMRLEEATERERRRLEAESRVAEEKIRRDRVRAELEAREREEERKRAAERERIARETASLQQQAELDAAWAGKKIATVTTSNSAFTGAPKQVSPSGSEESDEWISTSKEVKHTKTAPWAAKVEAPQKSEKTLLEIQKEEERKFKVEQEKNAKLKAKEQASNITSAAAIAGDKSGGLWGASKTWAAPESNSSKSYVSPFLDGPSLEAANKMALQKKNSQPKIAVPAKSAPTSAKVATPVKAKATAVAVSSPATNQKTKKTKEQVATDELQQWFVKRFQQFSTQVDSSTLFDCIMSLENPNEVEDIVMSYLDESKTVKEFVREFIKRRIAMRAAGGRPDADDLTSARTAAAAPSDSNSGSNSNSGNGQGKKKKKTQKQVLDGNILGFRGTAAADRLNKGEIDAVPSAPVNPSRR
What are the official names of this protein?
GYF domain-containing protein gyf-1.
Protein: TGT_SALNS
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKSDTSPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTEFYQRQGRPVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: Y4BJ_SINFN
Sequence: MLSSRLGLFNMFRLLAAILVFTGLASAVNADLLQTGGSRWVVLASTRDLDNAIGIANLYQHRFDDVRVAEASNGWLAVIAGPVSIARGAKAAREELWSAGGFPPDLFLSNGQSLRRTVWEPPKGRPIPTWSYKGGQPLVFSAGGLEIEVSHLAEGNTRYPSITLRRAGRLLIKEVLKGSESFGDNMNAEVRLVWLDRAVAEPQIIFSSHWNGAHCCTVSKILTKVGNGWTSIEGATLDGGGYRLQDIDGDGSVELLSVDNSFLYTFAPYVFSSAPLVISKLDGDRLIDMRWNSAFRRYYRRELFGWEYRAKLEPEIWRKNGFLSAWLALKSVLGESDQAWTVVLENYDRSSEWPLTVCDAPLKEGVCPEEATREVSFPEALRDHLARNGYLGPQVAKIEETSKPTEQPSPADSTSTPAAPEKGAASSAGTGFFISKQGHLVTNHHVIKGCSAIEVRRPGQLRLPANIVAVDPTNDLALLRVESDTGAYASVRVETRLGESVAVFGYPLSHVLASGGNFTLGNVTALAGLGNDTRFIQISAPVQPGNSGGPLIDSYGNVIGVVTSKLDALAALAVTGDIPQNVNFALRGASLYAFLLSYGISPVAGSNTQKLDAPELAERASSFSVAVTCE
What are the official names of this protein?
Uncharacterized protein y4bJ.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCSA_STAA8
Sequence: MLCENCQLNEAELKVKVTSKNKTEEKMVCQTCAEGHHPWNQANEQPEYQEHQDNFEEAFVVKQILQHLATKHGINFQEVAFKEEKRCPSCHMTLKDIAHVGKFGCANCYATFKDDIIDIVRRVQGGQFEHVGKTPHSSHKKIALKRKIEEKNEYLKKLIEIQDFEEAAIVRDEIKALKAESEVQHDDA
What is the function of this protein?
Activates the phosphorylation activity of the protein-arginine kinase McsB (By similarity).  May function as an important molecule for oxidative tolerance in various types of stress including that of heavy metals.  Binds to Cu(2+), Zn(2+), Co(2+) and Cd(2+) via its CXXC metal binding motifs (PubMed:22126623).
What are the official names of this protein?
Protein-arginine kinase activator protein.
Protein: CSF2_CEREL
Sequence: MWLQNLLLLGTVVCSFSAPTRPASPVTRPWQHVDAIKEALSLLNHSSDTAAVMNETVEVVSEMFDSQEPTCLQTRLKLYKQGLRGSLTSLSGSLTMMARHYEQHCPPTQETSCETQTITFKSFKENLKDFLFIIPFDCWEPAQK
What is the function of this protein?
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
What are the official names of this protein?
Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF.
What is the protein family that this protein belongs to?
Belongs to the GM-CSF family.
What are the subcellular locations of this protein?
Secreted.
Protein: AAKB2_MOUSE
Sequence: MGNTTSERVSGERHGAKAARAEGGGHGPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEFVPWQQDLDDSVKPAQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSETSCRDLSSSPPGPYGQEMYVFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI
What is the function of this protein?
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.  In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.  AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.  Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.  Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) (By similarity).
What are the official names of this protein?
5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2.
What is the protein family that this protein belongs to?
Belongs to the 5'-AMP-activated protein kinase beta subunit family.
Protein: STA5B_BOVIN
Sequence: MAVWIQAQQLQGDALHQMQALYGQHFPIEVRHYLSQWIEGQAWDSIDLDNPQENIKATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGTSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLAQLNPQERLSRETALQQKQLSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHFCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNSSSSHLEDYNGMSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRLGDLSYLIYVFPDRPKDEVYSKYYTPVPCEPATAKAVDGYVKPQIKQVVPEFVSASADSAGGSATYMDQAPSPAVCPQPHYNMYPQNPDPVLDNDGDFDLDDTIDVARRVEELLGRPMDSQWIPHAQS
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription.  Mediates cellular responses to the cytokine KITLG/SCF and other growth factors.  Binds to the GAS element and activates PRL-induced transcription.  Positively regulates hematopoietic/erythroid differentiation.
What are the official names of this protein?
Signal transducer and activator of transcription 5B.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Protein: GALM_ACICA
Sequence: MKKLAILGVTVYSFAQLANAATLNVKSYGTTQNGQKVDLYTMSNNNGVSVSFISFGGVITQILTPDAQGKQNNIVLGFDDLKGYEVTDTKEGIHFGGLIGRYANRIGNAKFSLDGKTYNLEKNNGPNSLHSGNPGFDKRVWQVKPLVSKGETVKASLKLTSPNGDQGFPGKLDVEVIYSLSDQNEFKIEYKAKTDQPTVVNLTNHSYFNLSGAGNNPYGVLDHVVQLNAGRILVTDQNSLPTGEIASVAGTPFDFRMPKAIVKDIRANNQQLAYGYGYDQTWVINQKSQGKLNLAAIVVDPKSKRTMQVLTTEPSVQMYTADHLLGNIVGANGVLYRQADALALETQHFPDSPNQPTFPSTRLNPNQTYNSVTVFKFGVQK
What is the function of this protein?
Mutarotase converts alpha-aldose to the beta-anomer.  Active on D-glucose.
What are the official names of this protein?
Aldose 1-epimerase, Galactose mutarotase, Type-1 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the aldose epimerase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PARC_STRPN
Sequence: MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVIIEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELADIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTPWRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAGVKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKNKPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNGSFISDTISDEEVFDAYLQEVVTEDK
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA (PubMed:17375187, PubMed:20596531).  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GSA_VIBCM
Sequence: MTKSAELYQKAQTTIPGGVNSPVRAFNGVGGSPIFIDRADGALIFDADGKAYIDYVGSWGPMILGHNHAVIREAVIQAAQRGLSFGAPTEMEITMAELVSELVPSMEQLRMVNSGTEATMSAIRLARGYTGRDKIIKFEGCYHGHADSLLVKAGSGALTLGQPSSPGVPADFAKHTLTARFNDLDSVRELFAANQGEIACIIVEPVAGNMNCIPPVEGFHEGLREICDQEGALLIFDEVMTGFRVALGGAQAHYNIKPDLTTLGKVIGGGMPVGAFGGRREVMQYIAPTGPVYQAGTLSGNPIAMAAGYACLNLLREEGNEKRLAAKTKQLADGFKSLADQHGIPLLVHQVGGMFGFFFTEQETVTCYEDVARCDVERFKRFFHLMLQHGVYLAPSAFEASFTSLAHGSKEIEATLEAADRSFAILAAEAKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMI_HELPJ
Sequence: MLYFLPTPIGNLADITLRTLEVLERCEVFLCEDTRVSKRLLHLLAKNPIISHSFPNIAAKKREFIAFHSHNDQEFLNQIEPSFFDKEIAVMSDAGMPSLSDPGMSLVAYALKHNLQYDVLPGANALTTAFCASGFLEGRFFYAGFLPHKSKERRLRIIKILNALAYLEEKTPVVFYESPHRLLETLRDLNDLAQGMHLFAAKELTKLHQQYYLGEISQIMTQLQKSNIQGEWVLVLLNEKKIEPSMGLSALLELDLPPKIKAKMEAAMTQKNAKELYFQRLLEEKKQCD
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNB2_XENLA
Sequence: MATRRAAIPREADNILGGAMRSKVQMNSRRAALGEIGNKVTVRGKPPAVKQSSNAVAKPSKMAATKVANVKTKHVPVKPVVAEAAPKVPSPVPMDVSLKEEELCQAFSDALTSVEDIDADDGGNPQLCSDYVMDIYNYLKQLEVQQSVHPCYLEGKEINERMRAILVDWLVQVHSRFQLLQETLYMGVAIMDRFLQVQPVSRSKLQLVGVTSLLIASKYEEMYTPEVADFVYITDNAYTASQIREMEMIILRLLNFDLGRPLPLHFLRRASKSCSADAEQHTLAKYLMELTLIDYEMVHIKPSEIAAAALCLSQKILGQGTWGTTQHYYTGYTEGDLQLIMKHMAKNITKVNQNLTKHVAVRNKYASSKLMKISTLPQLMAPLITELAASLS
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: PANB_NATPD
Sequence: MRAKDIRAKAGDEPITMLTAYDAPTAEIAEAAGVDVLLVGDSVGNTRLGYDSTLPVTVDEMASHTAAVARATDDALVVADMPFLSFGADEADAVDNCGRMLKEADADAVKLECGPHTVSLTKTLSDLGIPVQAHLGLTPQRENETGLYRQGTDEESANRILELAREHEAAGAFSLVLEHVPANLAASVTDALSIPTIGIGAGPDCDGQVLVVDEVVGLAEGTAPFSKRFGDVRGEMREAIEAYTDAVDSGSFPGDEHSHYEDDIEDIY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_PACAQ
Sequence: MEEFQVYLELNRSRRHDFLYPLIFREYIYALAHDHGLNKSMIFLENQGYGNKFSSLIVKRLIIRMDQQNHLIISANDSNQNPFFGHKKNLYSQMISAGFAVIVEIPFSLRLVSYSQGEEVAKSHNLQSIHSIFPFLEDKFSHLNYVLDVLIPYPIHLEILVQALRYWVKDASSLHLLRFSLYEYCNLKSFITPKKSISIFNPRLFFFLYNSHACEYESIFLFLRNQSSHLRSTSSGVFLERIYFYGKIDYLVEVFSNDFQNNLWLFKDPFTHFIRYQGKAILASKDTSLLMNKWKYYFVDLWQYYFYMWSQSGRFRINQLSKYSLDFLGYLSSVRLNPSVVRSQMLENSFIIDNAMKKLDTRIPIISLIGSLSKAKFCNTLGHPISKPTWADSSDSDIIDRFVRICRNLSHYHSGSSKKKSLYRIKYILRFSCVKTLARKHKSTVRAFLKRLGSEFLEEFFTETEEEHFFSLIFPRVFFTSRKLYRGRIWYLDIICINALVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.