PharMolix/UniProtQA huggingface dataset:
Protein: Y250_MYCTU
Sequence: MSTTAELAELHDLVGGLRRCVTALKARFGDNPATRRIVIDADRILTDIELLDTDVSELDLERAAVPQPSEKIAIPDTEYDREFWRDVDDEGVGGHRY
What are the official names of this protein?
Uncharacterized protein Rv0250c.
Protein: Y422_STRS7
Sequence: MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYIDYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFSKAYVSIWYKRYLELKNR
What are the official names of this protein?
UPF0374 protein SZO_04220.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: UMPS_BOVIN
Sequence: MAAADALLGSLVTGLYDVQAFKFGNFVLKSGLSSPVYIDLRGIISRPSILNQVAEMLFQTAENAEINFDTVCGVPYTALPLATIVCSTHEIPMLIRRKEKKDYGTKRLIEGAVNPGDTCLIIEDVVSSGSSVWETAEVLQKEGLKVTDAVVLVDREQGGRDNLQARGIRLHSVCTLSTVLCILEQQKKINAETVERVKRFIQENAFVAANPNDSLPSVKKEPKELSFGARAELPGTHPVAAKLLRLMQKKETNLCLSADVSESRELLQLADALGSRICLLKIHVDILNDFTLDVMKELTTLAKRHEFLIFEDRKFADIGNTVKKQYEGGVFKIASWADLVNAHAVPGSGVVKGLEEVGLPLHRACLLVAEMSSAGTLATGSYTEAAVQMAEEHSEFVIGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYHSPQEVIGKRGSDIIIVGRGIIASANQLEAAKMYRKAAWEAYLSRLAV
What is the function of this protein?
Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP).
What are the official names of this protein?
Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the OMP decarboxylase family.
Protein: PTH_ONYPE
Sequence: MKLIVGLGNPGTKFVNTRHNVGFAVVDSFLSQNKYQILKEDKTDHIYQINFNHHQSLLIKPQTYMNLSGEVVKKIINKYRIKIENILVIVDDIYLDEGKLKLKMQGGHGGHNGLRNIIDRLGTKQFKRLKIGVSLDSCMPLDQYLLTPVNASSQKNILKNINIINKIIFNFIQDVDFNILMNGYNSKL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_CHLT3
Sequence: MTIEEALLGLLDGQTLISSEMESIMSEIMDGQISPIKIAAFLVLLRQRGEEVEEIYGAARAILNHAEQPILEGDPIDTCGTGGDGANTFNISTAASLIAHACGVKVAKHGNRSISSRCGSADVLEAMGFKIDLPKKETEELFKETGFVFLFAPIFHKAMKNVAPVRKELGLRTIFNMLGPLINPARTQRQIIGVYSKDLTGMFAQVLRQFDAKHCLILHGQTDEGGILDEPSVCGPTYISELQHGTVRTYTVHPEDFGLRRHSISQLKGGDARENAQIIWQILDKNGPEAREDAVVFTAGMACYVAELTPSIKEGIDKARQAIHSGAAKQSVERLLEKHRNLVI
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RADA_SULAC
Sequence: MSNDGKKVKSLSDLSGVGQNILNKLVEAGYSSLEAVAVATPQDLSVAAGIPQTTAQRIIKEAREALDIRFKTALEVKKERMNTKKITTGSQALDGLLGGGIETRTMTEFFGEFGSGKTQLCHQISISVQLPQEKGGLNGKAVYIDTEGTFRWERIEAMAKGAGLESDIAMNNIYYMRAINSDHQMAIVDDLQELITKDPAIKLIIVDSITSHFRAEYPGRENLAVRQQKLNKHLHQLVRLAEMYDIAVIITNQVMARPDMFYGDPTTAVGGHTLYHVPGIRVQLKKSRGNKRIARIVDAPHLPEGEVVFAITEEGVRDAEE
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: NRDI_DEIRA
Sequence: MLRLVYDSLTGNVRHFAETLAAELHVSPMRVQDPAPTDAYLLLTYTFGSGEVPASTRRLLTTHGHLLRGVVASGSYHWGHNFARAADVIAAEYRVPVVAKLNKGGTAADRAAVRRWLLHYAESAPPFPTSCTGEPTPWNAG
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: ATPB_CRETR
Sequence: MRSNPTXSGSEVSAVEKKNLGRIVQIIGPVLDVAFPPGKMPYIYNALVVQGRDNEQMNVTCEVQQILGNNRVRAVAMSDTDGLMRGMEVIDTGVSISVPVGGATLGRIFNVLGEPVDKLGPVDTKTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEENIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGTLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLKT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: LIPB_NITEU
Sequence: MFTVTVKNMGTTEYLTAWQAMKNFTAQRTCETPDEIWLLEHPPVYTQGIAGKPEHLLFPNQIPVIKTDRGGQITYHGPGQIILYLLLDLHRWRLNIRQLVRKMEGAVIDLLSEYDVVAQGDENAPGVYVDGAKIASLGLKIRRGACYHGIAFNADMDLTPFTAINPCGYRGLRVTQAKDLGIADCKEMLATKLAQSFINQLTDV
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSB_YERPB
Sequence: MLYTVSHSPYHCDLSALLRLATSEDDILLLQDGVIAALKESETLKLLLNNPASLFVLEDDVIARGLVGQISDNATLISYTHFVDLTLRHQQQLAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG22_KLULA
Sequence: MSYEAVPAENSAFIPDQAKRNIKGWYFYCFSSEPFIVSAVSTYVPLLLEQFGRINGVKLDDHSLRCEVNDDKCVLPMFNGRWFIDTSSFALYTFSLSVLFQTLLVISVSGIVDKCQSIAFKKRVLLFFGTVGALATWFIGTLRSDQYYVLPLLAIVGNCSYGVINVVGNSLLPVFVGFLVGNEDQLEVDIKTSIISGRGASYGYFSALIVQLFSILLVKQSKNHDNLQIAILFVGLWWLLWQIPIAFLLQDIPRDTDQEQHEFTWANTGNYMEYGWNSLWESLKHARLLKDVVIFLIGWFIISDSLTTINSTAILFAKTELKMTAINLITLSIITMVMAMLGAVYIPHLLSERLRLPLQQVLIIIIIWSSVIPLYGMTGFVFQNIGLKHKFEMYILGVWYGVSLGGLAAVSRSLFSLLVPRGKESTFFSLFSVTDKGSSILGPLLIGLITDKTHNIRYAFYLLFLFLVVSLPVFHGLDVERGKREARQLSTM
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: PROB_CUPMC
Sequence: MQSVIAQAKRIVVKVGSSLVTNDGKGLDHDAIARWAAQIAKLRGTGKEVVLVSSGAIAEGMQRLGWARRPKEIHELQAAAAVGQMGLAQVYESQFGRYGIRTAQVLLTHADLADRERYLNARSTLLTLLSLGVVPIINENDTVVTDEIKFGDNDTLGALVTNLIEGDALVILTDQRGLYTADPRKDPNAEFVHEALAGTPELEAMAGGAGSSIGRGGMLTKILAAKRAAKSGAHTTIASGREADVLGRLAAGEAIGTQLLAPTGRLTARKQWMADHLQLRGRVIIDAGAVEKLTSGGKSLLPIGVVEVQGEFARGEVIACASPEGKEVARGITNYSSAEARLIARKPSSEIESVLGHLNEPELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_WOLTR
Sequence: MNEELLNEIPLLEDKAVFEIESASSLQDLEKVRLSYLGRKGVIKAYFDDLRKVEDTEKKRDLGAIINVLRNKLDQLIMNKESILKAEEVNFKLQNEAIDITLPVRPEKIGRAHPLSKVMNEVKLIFAHMGFRAVNGPDIEDEFHVFDALNTPSHHPAREEQDTFYLKNKINDKRMMLRTHTSSMQIRAMKKAKTFPIKIVAAGRVYRNDFDATHTPMFHQMEGLYVNENVNMGQLKFTIHHFLNKFFGDKELKIRFRNSFFPFTEPSAEVDISYKESKWIEVLGCGIVHPNVFQNVGIDHTKYSGFAFGIGIERLAMLKYQISDLRNFYDNKISWLSHYGFHFSSLR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_LEPBP
Sequence: MKSSILLDGKAISEKIRNRIQETLAKAKAEGKGIPTLATILVGNNPASETYVNMKVKACEKVGMHSRYIRLKEETTTEELLGEIRKLNLDPSINGILLQHPVPHQIDERKAFDEIALEKDVDGVTTISFGKLSMNSEAYYPCTPYGMVLLLQEYGIDVTGKHAVVVGRSPILGKPMAIMLTNLNATVTLCHSKTEDLPSLVKQADIIVGAVGKPEFIKAEWMKEGVVILDAGYNVGNVGDIEVSKAKDKSSYYTPVPGGVGPMTISVLLLQTMYSFLGQFSPKLESHVANR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: VM11_BOTMO
Sequence: AFSPRYIELAVVADNGMFTKYNSNLNTIRTRVHEMVNTVNGFYSSVNANASLANLQVWSIKDLIKVEKDSNKTLTSFGEWRERDLLPRISHDHAQLLTTIVFDNYVIGRSRSGKMCDPEQSVGVVRDHSKNNLWVAVTMAHELGHNLDMHHDDTCSCGAKSCIMASVLSKTKSYAFSTCSQNEYQTFLTKHNPQCILNEP
What is the function of this protein?
Zinc metalloprotease that displays fibrinogenolytic, gelatinase and weak hemorrhagic activities (PubMed:32946987).  Degrades the three chain of fibrinogen Aalpha-chain (FGA), Bbeta-chain (FGB), and gamma (FGG) (PubMed:32946987).
What are the official names of this protein?
Snake venom metalloproteinase BmooMP-I, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AROC_STRPG
Sequence: MRYLTAGESHGLSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGTRMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: COAX_ROSS1
Sequence: MLLTIDIGNTNIKIGVYQDERLTAHWRVTTERHRLADEYLVLLHNLFDLGGIDPREIDGCAISCVVPPLTGEFRTLCRTYFRVEPLMVNATTPTGLRYNVDTPAELGADRIANSLAAFRRYGGPVIVLAFGTATTFDVITADGEYIGGAIAPGIGISADALFRLAAKLYQVELVRPPSVIGKNTIHHMQSGVILGYAGLVEGLVNRMQAELGTSCPVVATGGLAELIAAETEAITTVEPYLTLEGLRLIYEMNRS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_ACTSZ
Sequence: MQCVNVELKERRYPIYIGEGLLTDSSVYPLKSGDKVMIVTNETIAPLYLETVTDTLNQIGCQVSHVLLKDGEKYKTLGSLNQIFTALLQENHGRDTTLIALGGGVIGDVAGYAAASYQRGIKFIQIPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPITVIIDTTTLNTLPKREVNAGLAEVIKYGAILDYPFFEWLERHIDNLVALNQQDLQYCIARCCRIKADVVARDETEKGDRALLNLGHTFGHAIETHLGYGNWLHGEAVAAGSMMAAALSEKLGNLARTDVARVEKLFARANLPTLSPDGMQPEDYLPHMMRDKKVLAGKLRLVLLKALGQAYVATDTDPALVLDAIYACTQTD
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_BIFLO
Sequence: MAAPKQAARKPRRRDRKSVPVGQAHIKSTFNNTIISITDPSGAVVSWASGGDVGFKGSRKSTPYAAGMAAESAARKAMEHGVKKVDVFVKGPGSGRETAIRSLQSAGLEVGSITDVTPQAHNGVRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: V2R_CANLF
Sequence: MLLASTTSAVPRTLSPPTPAGNGSRELLDTRDPLLVQAELALLSTVFVAVALSNGLVLGALARRVRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLILSLPQLFIFAQRDVGNGSGVLDCWAHFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHSSLVPGPAERAGGCRGGHRTGSPSEGARVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPQAPLEGAPFVLLMLLASLNSCTNPWIYAFFSSSVSSELRSLFCWARSRAPPSLGPQEESCATASSFLAKDTSS
What is the function of this protein?
Receptor for arginine vasopressin.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Involved in renal water reabsorption (By similarity).
What are the official names of this protein?
Vasopressin V2 receptor, V2R, AVPR V2, Antidiuretic hormone receptor, Renal-type arginine vasopressin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS18_BARQU
Sequence: MSEINQTVTRRPFHRRRKTCPFSGANAPKIDYKDIKLLQRYISERGKIVPSRITAVSQKRQRELANAIKRARFLGLLPYVIK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y506_BRUA2
Sequence: MTTHRKPSQEQGFLNGQFLLAMPGMSDERFARSVVYICAHSDEGAMGFIINQLQPVQFPDLLRQIGVIGEEDLIILPDRAQHMVVRNGGPVDRTRGFVLHSDDYMVDSTMPVSDDVCLTATVDILRAIYGGGGPERALMALGYSGWAPGQLEMEVAENGWLTCDAPLDMLFDSDIEGKYSRLMLHMGIDMSRLVFDAGHA
What are the official names of this protein?
UPF0301 protein BAB1_0506.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: AHPC_ECOLI
Sequence: MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFTFVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTGALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVASHPGEVCPAKWKEGEATLAPSLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.  Is the primary scavenger for endogenously generated hydrogen peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Alkyl hydroperoxide reductase protein C22, Peroxiredoxin, SCRP-23, Sulfate starvation-induced protein 8, SSI8, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_STRR6
Sequence: MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTPNKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTAHITVAVAEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: HEM1_STUS1
Sequence: MAFLALGINHKTASVDVRERVAFTPDQMVEALRQLCRVTPTREAAILSTCNRSELYLQQDEVEAEAVLAWLASYHRLSLDELKACAYVHVDDQAVRHMMRVASGLDSLVLGEPQILGQMKSAYAVAREAGSVGPLLGRLFQATFSTAKTVRTDTAIGENPVSVAFAAVSLARQIFSNLQRSQALLIGAGETITLVARHLHEQGVKRIVVANRTLERASALAAELGAHAILLADIPDELHNSDIVISSTASQLPILGKGAVEQALKRRKHKPMFMVDIAVPRDIESQVGELDDVYLYTVDDLHEVVAENLKSRQGAAQAAEELVAAGTEDFMQRLRELAAVDVLKAYRQHAERIRDDELSKAQRLLANGASAEDALAQLARGLTNKLLHAPSVQLKKLSAEGRVEALSMAQELFALHEGTEKP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SRCA_MOUSE
Sequence: MKALLLLCCFLASLLLSGQAEVEDASEEAPLRDRSHIDKTLMLNEDKPADDYSAVLQRLRKIYHTSIKPLEQSYKYNELRQHEITDGEITSKPMVLFLGPWSVGKSTMINYLLGLEDTRYQLYTGAEPTTSEFTVLMHGPKLKTIEGIVMAADSARSFSPLEKFGQNFLEKLIGIEVPHKLLERVTFVDTPGIIENRKQQERGYPFNDVCQWFIDRADLIFVVFDPTKLDVGLELEMLFRQLKGRESQIRIILNKADNLATQMLMRVYGALFWSLAPLINVTEPPRVYVSSFWPQDYKPDTHRELFLKEEISLLEDLNQVIENRLENKIAFIRQHAIRVRIHALLVDRYLQTYKDKMTFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFDLPNREAYKDFFGINPISNFKLLSQQCSYMGGCFLEKIERAITQELPSLLGSIGLGKNPGAPNCDKTGCGETPKNRYKKH
What are the official names of this protein?
Sarcalumenin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum lumen. Sarcoplasmic reticulum membrane; Peripheral membrane protein. Note=May associate with the sarcoplasmic reticulum membrane, via a calcium-dependent mechanism.
Protein: CLCN3_RABIT
Sequence: MESEQLFHRGYYRNSYNSITSASSDEELLDGAGVIMDFQTSEDDNLLDGDTAVGTHYTMTNGGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRNDMNASKIVDDIPDRPAGIGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGFALRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTANQDPASIMFN
What is the function of this protein?
Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (By similarity).  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (By similarity).  The presence of conserved gating glutamate residues is typical for family members that function as antiporters (By similarity).
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 3, Chloride channel protein 3, ClC-3, Chloride transporter ClC-3.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: AKAP1_RAT
Sequence: MAIQFRSLFPLALPGMLALLGWWWFFSRKKDRLSSNGKQVGTLKVGPAIEDRLPTEEACPGVLSVTPSVTQPPGKEEQRSMDRPLSDPPALPRTRQVRRRSESSGNLPSIVDTRLQAGQCSDENSKVVLSLMGDEAKSIPLGRPLFPKDLSFPYEAVEGCKQESALGRTPGRGWLSQCAASGENARETGGAEGTGDAVLGESVLEEGLLPQECVSEVEKSEFPILAPGGGGGEKVRSGPPQVDELLKKEEYIVGKLPSSFVGPVHSELVKDEGALVPQVKGSQDRSLARELDKDKTLPEKDQIEQTAFQIISQVILEATEEIRATTVGKTVAQVHPTPGTQPQGQEESCVPASQETSLGQEIPDPASTRTGATASPSAGAPPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLDGASNPRGDDTFVTCTSNNSQSVLSVTSLGLCSDPVSTSRLEDSCTETISSSGDKAVTPPLPDSTEPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQTVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSCYASL
What is the function of this protein?
Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane (By similarity).  Involved in mitochondrial-mediated antiviral innate immunity (By similarity).  Promotes translocation of NDUFS1 into mitochondria to regulate mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) activity (By similarity).
What are the official names of this protein?
A-kinase anchor protein 1, mitochondrial, A-kinase anchor protein 121 kDa, AKAP 121, Dual specificity A-kinase-anchoring protein 1, D-AKAP-1, Protein kinase A-anchoring protein 1, PRKA1, Spermatid A-kinase anchor protein 84, S-AKAP84.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Mitochondrion.
Protein: DIM1_BOVIN
Sequence: MPKIKSAASGRRRERQQQRGQLKSAGGLMFNTGIGQHILKNPLIVNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVIACELDPRLVAELHKRVQGTPLASKLQVMVGDVLKADLPFFDACVANLPYQISSPFVFKLLLHRPFFRCAVLMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.  Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Probable dimethyladenosine transferase, DIM1 dimethyladenosine transferase 1 homolog, DIM1 dimethyladenosine transferase 1-like, Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, Probable 18S rRNA dimethylase, Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.