PharMolix/UniProtQA huggingface dataset:
Protein: PDXH_RUEPO
Sequence: MSDRTGIFAGDDPFAIARDWLAEAERSEPNDANAIALATVDASGLPNVRMVLLKEIEPAAFVFYTNYESAKAIELEQAGKAAFVMHWKSLRRQLRVRGTITREEGPQADDYYASRSLKSRLGAWASRQSRPLSSRAALMAEVAKITAAKGPNPPRPPFWGGFRLTPVEIEFWADGAFRLHDRFVWRRNSAGESWVIQRLNP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RF1_STRPS
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNRDTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGGFKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIRARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKLDEVVDALVLYDQTQKLEELNK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TES_CANLF
Sequence: MELEAKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPREMDAQSTNRMYIPGGDRSTAAAVGAMEDKSAEHKRTQYSCYCCKQSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: CSE1_SCHPO
Sequence: MDDIPTLLARTLNPTTSKSAEEALKVWELQDSSFALKLLNIVAEDTVDINIKLAASLYFKNYIKKHWDSEEGASIRISDEVAELIKREIINLMLKSTTIIQVQLGEVIGYIANFDFPDRWDTLLPDLISKLSAVDMNTNIAVLSTAHAIFKRWRPLFRSDALFLEIKYVLDRFCEPFLALFVQTNNLLRNGPQDAESLNSLFQVILLECKLFYDLNCQDIPEFFEDHMSEFMTAFLNYFTYTNPSLEGDEGETNVLIKVKASICEIVELYTLRYEEVFTMLYDFVNVTWTLLTTLTPDEKYDGLVGKAMAFLTSVIRIRKHAEFFQQDQVLQQFIELVVLPNICLRESDEELFEDDPLEYVRRDLEGSNSDSRARSAIVLVRGLLDHFDQKITSVVSTHINANLQQFSTNPSLEWNKKYVALQLFSAIAIKGQSTRLGVTSINLMVDVVAFFENNIKPDLLQPAGVIHPMVLAEDIKYVFTFRNQLNSQQLIDIFPTILRFLEMPSFVVYTYAAIALDQLLTVRHNHVHIFTSLLIAPHILPALNQLFLIVESASTPQKLAENDYLMKAVMRIIIMSQEAILPAASLLLQHLTKITEEVSKNPSNPKFNHYLFESIGALIRSLSKSGPQTVSQLENALLPVFQNVLIEDVTEFIPYVLQLLSQLVEASGNEPLPDFVVNLIQPCLSPALWDSKGNIPALVRLLRAMIFRGPQIFISNKFVEPVLGIFQKLISSKVNDHFGFDLLDRVFTVFNANILAPYINHIFFLLLSRLKNSRTERFVLRCTIFFFFVASEQTGTCGPDNLIQGVDAVQSGVFGQLMTSIILPQAQKLALPLDRKISALGLLRLLTCDLVLAPDAIYENLIIPLLTCILKLFEMPIEQAQTDADEELFMDEIDADSMSFQASFSRLATTGGKRVDPFPQITDLKQYCATEMNLANRNMGGRLSQIISTHLPGDGQSVLQSYGYVI
What is the function of this protein?
Export receptor for importin alpha.  Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity).
What are the official names of this protein?
Importin-alpha re-exporter, Cellular apoptosis susceptibility protein homolog.
What is the protein family that this protein belongs to?
Belongs to the XPO2/CSE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus envelope.
Protein: LEUD_XANP2
Sequence: MEKFTVLEGVAAPLKLVNVDTDMIIPKQYLKTIKRTGLGTGLFSEMRYKDDGSDNPDFVLNQSAYKNAKILVAGDNFGCGSSREHAPWALLDFGIRCVISTSFADIFYNNCFKNGILPVVVSKEDLDKLFDDADRGANATLTIDLPAQEIRGPDGGVVKFEIDPFRKRCLIEGLDDIGLTLEKAPAIAAYETAKGAEQPWL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PA2AF_AUSSU
Sequence: MYPAHLLVLLAVCVSLLGAASIPPQPLNLVQFSYLIQCANHGSRATWHYTDYGCYCGSGGSGTPVDELDRCCQTHDNCYGEAEKKGCYPKMLAYDYYCGGDGPYCRDIKKECQRFVCDCDVEAAKCFAKAPYDKENYNIKTRCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Acidic phospholipase A2 S12-65J, svPLA2, ASPLA15, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UCRQ1_ARATH
Sequence: MGKQPVKLKAVVYALSPFQQKIMTGLWKDLPEKIHHKVSENWISATLLVTPVVGTYWYAQYFKEQEKLEHRF
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 8-1, mitochondrial, Complex III subunit 8-1, Complex III subunit VIII, Ubiquinol-cytochrome c oxidoreductase subunit 8-1, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C.
What is the protein family that this protein belongs to?
Belongs to the UQCRQ/QCR8 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: POXA_DICDI
Sequence: MRLNLISFFIIFTILVSISNSQEFRSYTGEGNNKQNPKQGSIFTPFIRLANPIKFNKNGFPNITNQPSRAISNIIFDQQTHIGSKEHLTDMFNMWGQFLIHNMALSKPEPNSWPIKVPKCDQYFDPACIGNKTMNYFRTRATEVPCDVGKTVVDEDGKCYEQINSLGSYIDGNVLYGNSEEICKNLRSLSGGEMKMTVTDVGDLPPKNVPGVPMDNDANLFPIDQLYSVGERRGNENPGLLSIHTLLLRDHNRLARKFARLHPEWDDERVFQQSRSCIIEQIQKITYDEYLPTTLGSFPSYTGYDANVNAQVSNEFTTTAFRFGHSEVGPFMEYYSENGTRLQPLPIKFSYFNPHALNRGVEPLIRGLIINEEENIDIYMISDLRNFLFGKPGQGGLDLASRNLQRNRDHGIPPYNSLRRQLGLRPVQTWSDITSDPQIQNRLKNAYKSVDDIDSYVGGLAEDHMEGSCVGQTFYLIIYEQFFRTRAGDRFWYETPEMRMVNRECETTTFAEVIKRTTSNIGYVQPNVFRK
What are the official names of this protein?
Peroxinectin A.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOXK_CYBMR
Sequence: MKFSFVYGLTGFLAATSSALPSEILSTGYERSALEKRGDGYLIMCKNCDPNTGSCDWKQNWNTCVGIGANVHWMVTGGSTDGKQGCATIWEGSGCVGRSTTMCCPANTCCNINTGFYIRSYRRVE
What is the function of this protein?
This toxin kills sensitive strains of yeast.  It inhibits beta-1,3-glucan synthesis.
What are the official names of this protein?
Killer toxin HM-1.
What are the subcellular locations of this protein?
Secreted.
Protein: TCPQL_HUMAN
Sequence: MDSTVPSALELPQRLALNPRESPRSPEEEEPHLLSSLAAVQTLANVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLREAAQTQAENSGDGTAFVVLLTEALLEQAEQLLKFGLPRPQLREAYATATAEVLATLPSLAIQSLGPLEDPSWALHSVMNTHTLPPMNHLTKLVAHACWAIKELDGSFKPERVGVCTLHGGTLEDSCLLQGLAISGKLCGQMAAVLSGARVALFACPFGPAHPNAPATACLSSPADLAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKYGIVVIQARSRMEIIYLSEVLDTPLLPRLLPPQRPGKCQRVYRQELGDGLAVVFEWECTGTPALTVVLRGATTQGLRSAEQAVYHSIDAYFQPCQDPRLIPGAGATEMALAKMLSDKGSRLEGPNGPAFLAFARALKYLPKTLAENAGLAVSDVVAEMSGVHQGGNLLMGVGAEGIINVAQEGVWDTLIVKAQGFRAVAEVVLQLVTVDEIVVAKKSPTHQQIWNPDSKKTKKRPPPVEKKKILGMNN
What is the function of this protein?
Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis.
What are the official names of this protein?
Putative T-complex protein 1 subunit theta-like 1.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_ASCSU
Sequence: MEGANVNEDERKYLRQIKHIIDEGDKVIDRTGVGTLSLFGLHSTYSLRNGVIPLLTTKRVYWKGVVEELLWFIKGDTDAKRLSAKGVKIWDANGSREFLDSQGFKDRPEGDLGPIYGFQWRHFGAEYHGTDADYKGQGVDQLADVIEQIKNNPNSRRIILNAWNVKDLHQMALPPCHTLAQFAVKNGELSCQLYQRSGDMGLGVPFNLASYGLLTHMIAHVCALKTGFLHHVLGDAHVYLNHIDALKEQLSRDPRPFPTVHFEGRIDSIDDFTAESIILNGYNPMAPIKMPMAV
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: EFTS_CHLPM
Sequence: MSQISAKDVKDLRDTTGVGMMDCKKALEETGGDMQKAVEYLRKKGAALAAKRAEKDASEGMICIKVAEDRKAGVILELNCETDFVARGEVFTGFAGALGQLALEGSAASAGALLGMTLSAEFGGEKVEDAIKTMTGKLGEKIELKRLVFCDAADGLVEAYVHPGAQLGAIIHIASAQPDSARELARDLAMQVAAAAPIVVDRSAVPEELIAKESDIYRQQALGQGKKEEFVDRIVQGRIEKYYQEVVLTEQAFIKVNNMKVSDVLGEFRKQHEAAVEIREFVRYQLGE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRBB1_HUMAN
Sequence: MSQAAKASASATVAVNPGPDTKGKGAPPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin B1, Beta-B1 crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: RL9_STRPJ
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAVGELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAEELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: TRMD_NOSS1
Sequence: MRFDIVTLFPDCFTSVLSSGLLGKALAKQIAQVNLVNPRDFTTDKHRKVDDEPYGGGVGMLMKPEPIFSAVESLPILERREVILMSPQGQTINQPLLRELVSNYEQLVVICGHYEGVDDRVLHLVTREVSLGDFILTGGEIPAMALINGVVRLLPGTVAKTESLTAESFEEGLLDYPQYTRPANFRGWKVPDVLLSGNHAAIAQWRYEQQIKRTSDRRPDLLEKWQQEKKQGSREQGAREAGGVGGEITTDD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCEA_LISMO
Sequence: MFKTNVEQNNVPVFGSFESGQDLPEKRMNKESVDPRIAYQLVKDQLIDEGSARQNLATFCQTYMEPEAEQIMAETMEKNAIDKSEYPQTAKLESSCVNMLADLWNVDESEHYMGTSTVGSSEACMLGGMAMKFRWRSAALKNGLDIHAKKPSLVISSGYQVCWEKFCVYWDIELREVPMSEEHLSINTDIIMDYVDEYTIGIVGILGITYTGKFDDIMTLNDLVEDYNNTHDNEVVIHVDGASGAMFTPFVEPGLEWDFRLPNVVSINTSGHKYGLVYPGVGWILWRDKEYLPEELVFDVSYLGGHMPTMAINFSRSASQIIGQYYNFLRFGYEGYRQIHMRTRDGALQLSQAVAETGLFEIYNDGANLPIVCYKLKDDANVAWTLYDLADRLQMKGWQVPAYPLPKEMGNTIIQRYVCRGDLGQNMVTAFKNDLSESIEELNNAHILYHDVNTSKTHGFTH
What is the function of this protein?
Converts internalized glutamate to GABA and increases the internal pH.  Involved in glutamate-dependent acid resistance in gastric fluid.
What are the official names of this protein?
Glutamate decarboxylase alpha, GAD-alpha.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: CLPP2_PROMA
Sequence: MPIGTPSVPYRLPGSQFERWVDIYTRLGAERILFLGQEVTDGVANSLVAQMLYLDSEDSTKPIYLYINSPGGSVTAGLAIYDTMKYVKSDVVTICVGLAASMGAFLLSAGTKNKRLALPHSRIMIHQPLGGTSQRQASDIEIEAKEILRIKDMLNRSMAEMTGQPFEKIEKDTDRDYFLSAKEAKDYGLIDKVISHPNEA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_MAGSA
Sequence: MGKHAENGNAAAERPRFFGRRQGKALRRNALGLIEDLLPRLTVAVPEPDERVEPALLFPGAVRSVWLEVGFGGGEHLAQLAEDNPDIGLIGCEVFRNGIASLLGHVQARQLGNNVRVFPEDVRLLLPALPDGSLGRVFVLFPDPWPKTRHADRRFISPETLDVLARVLESGGELRVASDDPIYVAWAARHLDAHPAFEKILATADRSAVPADWPATRYEQKCITGRAPVFFLYRRRAR
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: OBG_VIBVU
Sequence: MKFVDEAVIKVQAGDGGNGVVSFWREKFVTKGGPDGGDGGDGGDVYIQADENLNTLIDYRFQRFYEAERGQNGSGGNCTGKRGKDITLRVPVGTRAVDIHTNEIVAEVAEHGKKVMVAKGGWHGLGNTRFKSSVNRAPRQKTMGTKGEIRELRLELLLLADVGMLGLPNAGKSTFIRAVFAAKPKVADYPFTTLIPSLGVVSVVPEKSFVVADIPGLIEGAADGAGLGIRFLKHLERCRVLLHMIDIFPIDQSDPVQNALTIIDELEQYSEKLANKPRWLVFNKVDLVSEEQADEIIQEVIDALGWEEQYFKISAVNRQGTKELCYKLADFMEQLPREEQEVSEEEKVNFMWDYHPDANQGEVITEDDDDDWDDWDDEEDDGHVIYVRE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOSP_SHRV
Sequence: MAESIEMGEELVSSPSTLLALKGKLENPSPDDATILGILGKKTPTVKMEKGKGKGDPIEAFLLEFVDERRQVEANKRLRQYIRQLKMSHQEELTAHLERASAENRANLKSMMESQAESNKTTKTILATLITLRDHVIEEGSKKPRGLDKDQIKLERALGFERGYSSAIAIVNQLKVTEPSQVCKPSVRAAALSAMEKGEFESSGEVFKAVVKRAKAELTK
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RIMO_THESQ
Sequence: MRVGIKVLGCPKNEADCEILAGVLRERGHEIVFDVKDADVVVLDTCAFIEDAKRESIDEIFSFIDAKDQYSYKLVVKGCLVQRYYEELKKEIPEVDQWIGVVDPEEIANALEKGTDLVPNRPETVYRYRKRIDLEERPYAYVKISDGCDRGCTFCSIPSFKGSLRSRSIEDITHEVEDLLKEGKKEIILVAQDTTSYGIDLYRKQALPDLLRRLNSLNGEFWIRVMYLHPDHLTEEIISAMLELDKVVKYFDVPVQHGSDKILKLMGRTKSSEELKKMLSSIRERFPDAVLRTSIIVGFPGETEEDFEELKRFVEEIQFDKLGAFVYSDEEGTVAFNLKEKVDPEVAKRRQEELLLLQAEISNSRLDRFIGRKLKFLVEGKEGKFLVGRTWTEAPEVDGVVFVRGKGKIGDFLEVVIKEHDEYDMWGSVT
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_HV1Z8
Sequence: MRVMGIRMNYQHLWKWGIMLLGILMTCSVAEDLWVTVYYGVPVWKEATTTLFCASDAKSYEPEAHNIWATHACVPTDPNPREIEMENVTENFNMWKNNMVEQMHEDIISLWDQNLKPCVKLTPLCVTLNCTNAGGNKTTNGNNTTNQEEQMMEKGEMKNCSFNITTVISDKKKQVHALFYRLDVVPIDDDNSANTSNTNYTNYRLINCNTSAITQACPKVTFEPIPIHYCAPAGFAILKCKDKKFNGTGPCKKVSTVQCTHGIRPVVSTQLLLNGSLAEEEIIIRSENLTNNVKTIIVHLNESVEINCTRPDNKITRQSTPIGLGQALYTTRIKGDIRQAYCNISAAAWNKTLQQVAKKLGDLLNQTTIIFKPPAGGDPEITTHSFNCGGEFFYCNTSRLFNSTWNSSTWNNDTLNSEGTIKLPCRIKQIINMWQGVGKAMYAPPIEGLIKCTSNITGLLLTRDGGVNNSTNETFRPGGGDMKDNWRNELYKYKVVRIEPLGIAPTRAKRRVVEREKRAIGLGAVFLGFLGAAGSTMGAVSVALTGQARQLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVESYLKDQQLLGIWGCSGKHICTTTVPWNSSWSNKSLEEIWNNMTWIEWEREIDNYTGVIYSLIENSQIQQEKNEQDLLQLDKWASLWNWFSITKWLWYIKIFIMIVGGLIGLRIVFTVLSLVNRVRQGYSPLSFQTLLPAPRGPDRPEGIEEEGGEQGRDRSIRLVNGFSALFWDDLRNLCLFSYHRLRDLILIATRIVELLGRRGWEAIKYLWSLLQYWTQELKNSFISLLNATAIAVAEGTDRIIELIRRAFRAVLHIPRRVRQGLERALL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: LARO_LACPL
Sequence: MIKLVNICYDYPDTCGLKDLSLTVNSGDFICLMGPNGSGKSTLLRLLSGLASPTSGAYQFHDQPITTTYLADAQNRQQLHQRIGMVFQNTDVQLFNTSVTEEVAFGPRQLGLSAAMVAQRVADCLQLTDCANLADRVPYQLSGGEKKRVALASVLALNPEILLLDEPLNGLTIAAQQQMLTLLQRLQAAGKTIIMASHNYQQVQAVGERFIIFNSTHQVDADLTRADLDQQPARQAQLMTL
What is the function of this protein?
Probable ATP-binding component of the energy-coupling factor (ECF) transporter complex LarMNQO involved in nickel import.  LarO is presumably responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein LarO, Energy-coupling factor transporter ATP-binding protein LarO, ECF transporter A component LarO, Nickel transport ATP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GATD_METMA
Sequence: MEFKQGDRVRIEKNGTVYEGKVMPSMEGYITIKMKSGYNAGFSIDKVSITPLENNGEAANGGNGGKNGQKEPEPAKEKVSKPGLPKVSILSTGGTIASKIDYRTGAVTSQFTADDILAAIPELKEIADFKGRAISSILSENMDPDSWQNLARAVVEEIEAGADGIIVTHGTDTMMYSAAALSFMIETPVPIVFVGSQRSADRPSSDNAMNAICAARVAISDIAEVVVVMHGTSSDDYCEIHRGTKVRKMHTSRRDAFKSVNSLPIGTVDYDTGEIKTFIEYTGRGEKSLKFKPGMEPKCAIVKFTPGADPSVLDCYVDGGYKGLVLEGTGLGHVSTKWIPFIRRAVDAKMPVIVTSQCLNGRVCDRVYDTGRDMLKAGAIEGEDTLPETALVKLMWVLGQTDEFEKAVSMLGENLSGEINECTLR
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit D, Glu-ADT subunit D.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family. GatD subfamily.
Protein: TRPF_PELPB
Sequence: MTKIKICGITRLSDALESCRAGADALGFNFSSLSPRAITPERAKEIIEKLPPFVASTGIFVDQSPEEINAICRFCKLQIAQLHSEQYSPEDARAITEAKVIKVFRPEENFAVEEVFAFAEKSGINAFLFDAYRPDMAGGTGETIRASLATRIFNALGDSCYPILAGGLNESNIGEAIRSLQPYGVDTASGVECEPGIKDPVKIKAFIQAVRKTVF
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: DAPD_BORBR
Sequence: MTLDLQTTIEQAWENRANLSPVDASAEVRDAVEHTIDGLDLGRLRVAEKIDDQWIVHQWIKKAVLLSFRLHDNAVMGQGPLQFYDKVPTKFAGYGEAAFKAGGYRVVPPAVARRGAFIARNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVVEENSVLAMGVFLSQSTKIYDRATGKVSYGRVPSGSVVVPGSLPSEDGSHSLACAVIVKRVDAQTRAKTSINDLLRA
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y548_MYCPN
Sequence: MSTAKFVVPKAVENVRIEKFCLKLLPNIKLSQFFKLLRLGKVLLNNTKAKLGQRVSSGDTIVFQFAIEPYLHNHSEVVDLTQVQDDLQVIFEDEQLIVVDKPAGVVCQPDAKHELFNLANSLLKHCGYNQYFKNSLSFIPRFAHRIDRNTCGLVIGAKTNQALQELEAVFRHNLLMKQYQGLVFGPFNFKGTQKAYWAKDAYQALVTVKAKPFPNAKPITTIFENSKYLTKLDLSLLTIRLVSGKTHQIRACLNLLNTQLVGDRKYQLLQFKNRNRDFKHQALHATNLSFAQLDKQKFPLLANYSQRQFKSQLVPWFASLIKGVSI
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase MG370 homolog, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.