PharMolix/UniProtQA huggingface dataset:
Protein: VL1_HPV36
Sequence: MAVWHSANGKVYLPPSTPVARVQSTDEYIQRTNIYYHAFSDRLLTVGHPYFNVYDITGNKLEVPKVSGNQHRVFRLKLPDPNRFALADMSVYNPDKERLVWSCRGLEIGRGQPLGVGSTGHPLFNKLKDTENSNSYIKSSKDDRQDTSFDPKQIQMFIVGCTPCIGEHWDKAIPCEKERQDNRLCPPIELKTTYIEDGDMADIGFGNLNFKNLQESRSDVSLDIVNETCKYPDFLKMQNDVYGDACFFYARREQCYARHFFVRGGKTGDDIPDARIDNGTFKNQFFIPGADGQDQKTIGNAMYYPTVSGSLVSSDAQLFNRPFWLQRAQGHNNGILWANQMFITVVDNTRNTNFSISIYNNNGALKDINDYTAEQFREYQRHVEEYEISLILQLCKVPLKAEVLAQINAMNSSLLEDWQLGFVPTPDNPIQDTYRYIDSLATRCPDKTPPKEKEDPYKGLKFWDVDLTERLSLDLDQYSLGRKFLFQAGLQQTTVSGTKSVSYRGFTRGTKRKRKQ
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: THIE_NOSS1
Sequence: MVEPYSQQKQIQQVVYRILDANLDRAREGLRIIEEWCRFGLNSGQLAGECKYLRQEVAVWHTEELRAARDTAGDPGTDLSHPQEEQRSSIKALLQANFCRVEEALRVLEEYGKLYHPKMGQACKQMRYRVYSLETNLMGHQRHQLLRRSRLYLVTSPSESLLPTVEAALKGGLTLLQYRDKDTDDFVRLELATKLRQLCHSYGALFIINDRVDLALAVDADGVHLGQQDMPIATARQLLGPQRLIGRSTTNADEMQKAIAEGADYIGVGPVYETPTKIGKAAAGLGYVSYAAQHSSVPWFAIGGIDANNINDVIDAGAERVAVVRSLMQAEQPTLVTQYLISQLNRIKPES
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: Y206_METKA
Sequence: MYSMRVVIEETDVTIRADSKESVSSAAKAVKLHRSELDRYVAKDPAFVTAKVPVRTLEGAPEVAKLMSRAAEPFGVGPMAAVAGAIAELAARASEPTVIVDNGGDVQVRARRSVVVGLYVSDDHPLSGRIGFEIEGVLGVCTSSGKFGHSYSAGKADAVTVFAERASLADAAATAICNLTSGDDPEAAVQRALEFADDFTGDLIEAAVVIRGDFVGISGRPPKIVSLRGGRIKPARLEPTI
What are the official names of this protein?
UPF0280 protein MK0206.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: RS14_PSEA8
Sequence: MAKESMKNRELKRQLTVAKYAKKRAELKAIIANPNSSAEERWNAQVALQKQPRDASASRLRNRCRLTGRPHGFYRKFGLSRNKLREAAMRGDVPGLVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: GL_HCMVM
Sequence: MCRRPDCGFSFSPGPVILLWCCLLLPIVSSAAVSVAPTAAEKVPAECPELTRRCLLGEVFEGDKYESWLRPLVNVTGRDGPLSQLIRYRPVTPEAANSVLLDEAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA (PubMed:28403202).  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (PubMed:30057110).
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: RR2_CUSRE
Sequence: MTKRYWNINLEEMMGAGVHFGHGTRKWNPQMAPFIAAKRKGIHIINITRTARFLSEACDLVFDAARRGKKFLIVGTNNKAADSVARASRKARCHYVNKKWLAGMLTNWSITETRLNKFRDLRMEQKKGGLNHLLKRDATMFKRQLARLQTYLGGIQYMTGLPDIVIIVDQHKEYTALRECITLGIPTICLIDTNCDPNLSDISIPANDDAISSIRFILNKLVFAICEGRFSYLINP
What are the official names of this protein?
Plastid 30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid.
Protein: UPP_STUS1
Sequence: MPIREIRHPLIRHKLGLMRRADISTKNFRELAQEVGSILTYEATSDLPLEHYNIDGWCGPVQVEKISGKKITVVPILRAGIGMLDGVLSLIPGAKVSAVGIARNEETFKAQTYLEKLVPEIEQRLAIIIDPMLATGGSMVATIDMLKKAGCKEIRALVLVAAPEGIAAVEAAHPDVLILTASIDERLDEHGYIVPGLGDAGDKIFGTKQKDI
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RADA_HALS3
Sequence: MPESDLEELPGVGPATAEKLRDNGFDAFQSLAVANSAELSNTADIGESTAADVIQAAREAADVGGFETGATVLERREQIGKLTWNIPEVDDLLGGGVETQSITEVYGEFGAGKSQVTHQLAVNVQLPTEYGGLHGRAVFIDSEDTFRPERIDDMVRGLSDETLQAAMEAHEIEGSTDDEDTLTELVDAFLDKIHVAKGFNSNHQMLLAEKAKEIASEHEDGDWPVRMLTVDSLTAHFRAEYVGRGELADRQQKLNKHLHDLEKVGNLYNAAVLVTNQVQSNPDAFFGDPTKPIGGNILGHKSTFRMYLRKSKNDKRIVKLVDAPNLADGEAVMRVQDEGLKPE
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: MTLD_YERPP
Sequence: MKALHFGAGNIGRGFIGKLLADAGAQLTFADVNQPLLDELNKRKRYQVNVVGEQARVEEVKNVSAVNSGSPEVVALIAEADIVTTAVGPQILARIAATVAQGLITRHQQGNTRPLNIIACENMVRGTSQLKQHVFAALSEDEQIWVEQHVGFVDSAVDRIVPPSEAGSTDILAVTVETFSEWIVDGTQFKGQPPEIVGMELTDNLMAFVERKLFTLNTGHAITAYLGQLAGHQTIRDAILDPAVRQTVKGAMEESGAVLIKRYAFDPQKHAAYINKILSRFENPYLHDDVERVGRQPLRKLSAGDRLIKPLLGTLEYQLPHDSLVTGIAAAMSYRSEQDPQAQELVTLLAQLGPKAALAQISGLPADSEVVEQAVSVYNAMQQKLAH
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: FOLC_HUMAN
Sequence: MSRARSHLRAALFLAAASARGITTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGGPPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.  Unsubstituted reduced folates are the preferred substrates.  Metabolizes methotrexate (MTX) to polyglutamates.
What are the official names of this protein?
Folylpolyglutamate synthase, mitochondrial, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion inner membrane. Mitochondrion matrix. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: WCAE_ECOLI
Sequence: MLLSIITVAFRNLEGIVKTHASLAHLAQVEDISFEWIVVDGGSNDGTREYLENLNGIFNLRFVSEPDNGIYDAMNKGIAMAQGKFALFLNSGDIFHQNAANFVRKLKMQKDNVMITGDALLDFGDGHKIKRSAKPGWYIYHSLPASHQAIFFPVSGLKKWRYDLEYKVSSDYALAAKMYKAGYAFKKLNGLVSEFSMGGVSTTNNMELCADAKKVQRQILHVPGFWAELSWHLRQRTTSKTKALYNKV
What are the official names of this protein?
Putative colanic acid biosynthesis glycosyl transferase WcaE.
Protein: FOLD_HISS2
Sequence: MPAQIISGTELSKNIKFNVAEKIQHYLQQGKRAPGLAVILVGADPASQVYVGSKRRSCEELGIYSKSYDLPAETTEQELLTLIEQLNQDPQIDGILVQLPLPEKINSTKVIEHISPTKDVDGFHPYNVGRLCQRIPTLRACTPLGIMKLLETTGVDLYGQHAVIIGASNIVGRPMALELLLAGCTVTVTHRFTKDLKSHVHQADILVVAVGKPHIIPGEWIKEGAIVIDVGINRVDGKLVGDVQYDEASKKASFITPVPGGVGPMTVAMLMFNTLLAYESHS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y075_METJA
Sequence: MIMKFFDREREINEILGILDETPDNIYFIYGPINSGKTTLMMEIINRLKDDKKYRIFYYNLRGVRISSYSDFFDIMFEIREDNKFKQMVKDADVLVEGIKFIEKTAKLFNESIILPSDLAKVILSKQKGFDVFRYLERVFREMNKKGLKPVIIIDELQRLKGLKSNGELIDDLFNFFVRLTKELHITHCFCLSSDSLFIEYVYDRAELRGRADYILVDDFDKETALKFMDFLSEDILGRKLSEDEKELIYSYVGGKPKDVYDVIIKLKLGKELKDILEFMLKEEIQKLKYFLEDVKEDDEELYNKIVDALKIFKENYEIEDIKIPKNIREFLVKKNILFLNPIEGTLKPQSFLVWNAIKKLLNGH
What are the official names of this protein?
Uncharacterized ATP-binding protein MJ0075.
What is the protein family that this protein belongs to?
Belongs to the archaeal ATPase family.
Protein: I2B2B_DANRE
Sequence: MSSAAVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARQLKRAHGFQEGRSPGPVGKPGKDMQSINHAEPGSRPPQPLDRYPLTSDRPPRLGAEYQRQANGIPVPNGFPKPDEPPELNRQSPNPRRTGAIPPNLVPLVNGSMPPVHALNGRSVQMGIPPGALAEHVGKRADDMKDKHRADSMSDPSDGHKRVDEWTQKGKTVREMMTLQTLDSRFKKEHAALPHRMSYESSSGALKTDRGKHSRGIKRKTSPEPDGEGIAVKLNGEGQPWLPSPSEVLKMPSAALPGFAAAPPSTISPHSRTTPPEAATAVQNSQSPMAALILAADNAGTGSPKDAGNQVHSTTTSAAGRRNSGSPQSPSAGQRRPALGATGTAHIPGMDPQAGHPHSIPDSSVPPSSVPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP
What is the function of this protein?
Acts as a transcriptional repressor.
What are the official names of this protein?
Interferon regulatory factor 2-binding protein 2-B, IRF-2-binding protein 2-B, IRF-2BP2-B.
What is the protein family that this protein belongs to?
Belongs to the IRF2BP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL28_CANAL
Sequence: MPTRLTKTRKHRGNVSAGKGRIGKHRKHPGGRGKAGGQHHHRTNLDKYHPGYFGKVGMRYFHKQQNHFWRPEINLDKLWTLVDSEKKDEYLSKSSASAAPVIDTLAHGYGKVLGKGRLPEVPVIVKARFVSKLAEEKIRAVGGVVELVA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ERGI3_PONAB
Sequence: MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAERHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVRETYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT
What is the function of this protein?
Possible role in transport between endoplasmic reticulum and Golgi.  Positively regulates trafficking of the secretory proteins alpha1-antitrypsin/SERPINA1 and HP/haptoglobin (By similarity).
What are the official names of this protein?
Endoplasmic reticulum-Golgi intermediate compartment protein 3.
What is the protein family that this protein belongs to?
Belongs to the ERGIC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
Protein: RL23_SYNAS
Sequence: MTELHQIVKRMLVTEKSTLEKDEKNKYYFEVDRRANKIEIRKAVERLLKVTVDDVHVINIKGKKKRTGRIIGKRRDWKKAVVTLAQGNTIDIYHGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL37_METM6
Sequence: MTKGTPSQGKHNKGSNHIVCRRCGRRAFHVRKKVCAACGFGKSSKIKRFAWQWKKVTGKGNRVK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: CCG1_RABIT
Sequence: MSPTEAPKVRVTLFCILVGIVLAMTAVVSDHWAVLSPHMENHNTTCEAAHFGLWRICTKRIALGEDRSCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAISVFSLGFLIMGTICALMAFRKKRDYLLRPASMFYVFAGLCLFVSLEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAFVLLFLGGISLLLFSLPRMPQNPWESCMDAEPEH
What is the function of this protein?
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle.  Regulates channel inactivation kinetics.
What are the official names of this protein?
Voltage-dependent calcium channel gamma-1 subunit, Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Multi-pass membrane protein.
Protein: HIS1_AZOSB
Sequence: MSSITLALSKGRIFEETLPLLAAAGITPTDNPESSRKLIIGTNRPEVRLVIVRATDTPTYVQYGAADLGIAGKDVLIEHGGAGLYQPLDLNIARCRLCVAVRKGFDYAAATRPGGRIRVATKYINSAKAHFAGKGMHVDLIKLYGSMELAPLVGLADAIVDLVSTGSTLRANNLEEVEDIAPISSRLIVNQASLKLKRELIQPVLDAFAGAIKP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_PARD8
Sequence: MLTAKEIRESFKQFFASKEHQIVPSAPMVVKGDPTLMFTNAGMNQFKDIILGNVPRKYPRVADSQKCLRVSGKHNDLEEVGHDTYHHTMFEMLGNWSFGDYFKKEAINWAWEYLVEVLKLNPERLYATVFEGSPAEGLDRDNEAAGYWEQYLPKDHILNGNKHDNFWEMGDTGPCGPCSEIHIDLRSDEERAAVSGADMVNKDHPQVIEIWNLVFMQFNRKADGSLEPLPAKVIDTGMGFERLCMALQGKTSNYDTDVFQPIIKVIAGMAGTTYGTDKQQDIAMRVIADHIRTIAFAITDGQLPSNAKAGYVIRRILRRAVRYGYTFLDRKEAFMYKLLPVLIETMGDAYPELIAQKTLIEKVIKEEEESFLRTLETGIRLLDKKMEETKAAGKTVLNGVDAFTLYDTYGFPLDLTELILRENGMEADIEEFNKAMQKQKERARNAAAIETGDWITLKDGECKFVGYDLFECEAEILRYRQIKQKNKVLYQIVLDQTPFYAEMGGQVGDTGWLIADDEKIDVIDTKRENNLPVHLVTKLPKDVTATFTAKINVKKRIQCECNHSATHLLHEALREVLGTHVEQKGSYVSPDSLRFDFSHFQKVTDEEIRKVEILVGEKIRANFPLEEHRNMPIAEAKALGAMALFGEKYGDEVRVVKYGSSVELCGGTHIPATGMIGSLRVIGESSIAAGVRRIEAVTAEGAEQFVYAQQDLIRELRALMNHMPNLAQAMKKSIEENAEMKKQIEDYIREKSMRLKEEIVAKASESNGIKVMQFVGKANADAMKNVAFQIKAETTDSFVFVAGIIDDNKCTLMLMLSDDLVKEGLHAGKIVKEAAKHIQGGGGGQPHFATAGGKNMEGLSIAVGAVKEAVGVQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTA_PSEAE
Sequence: MHTFFIAPTGFGVGLTSISLGLLRALERAGLKVGFFKPIAQLHPGDLGPERSSELVARTHGLDTPKPLPLAQVERMLGDGQLDELLEEIISLYQRAAADKDVVIVEGMVPTRHASYAARVNFHLAKSLDAEVILVSAPENETLTELTDRIEIQAQLFGGPRDPKVLGVILNKVRGEADAANAEDGVADFARRLTEHSPLLRDDFRLIGCIPWQDELNAARTRDIADLLSARVINAGDYEQRRVQKIVLCARAVPNTVQLLKPGVLVVTPGDRDDIILAASLAAMNGVPLAGLLLCSDFPPDPRIMELCRGALQGGLPVLSVATGSYDTATNLNRMNKEIPVDDRERAERVTEFVAGHIDFEWLKQRCGTPRELRLSPPAFRYQVVQRAQKAGKRIVLPEGSEPRTVQAAAICQARGIARCVLLAKPEEVQAVAQAQGIVLPEGLEIIDPDLVRQRYVEPMVELRKGKGLNAPMAEQQLEDSVVLATMMLALDEVDGLVSGAIHTTASTIRPALQLIKTAPGYNLVSSVFFMLLPDQVLVYGDCAVNPDPSASDLAEIAVQSAASAQAFGIPARVAMISYSTGDSGSGVDVDKVREATRLAREQRPDLLIDGPLQYDAAAIASVGRQKAPNSPVAGQATVFIFPDLNTGNTTYKAVQRSADCVSVGPMLQGLRKPVNDLSRGALVEDIVYTIALTAIQADAQAPA
What is the function of this protein?
Involved in acetate metabolism.  In combination with LdhA and AckA, allows fermentation of pyruvate, enhancing long-term survival under anaerobic conditions.
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDFT1_ARATH
Sequence: MGSLGTMLRYPDDIYPLLKMKRAIEKAEKQIPPEPHWGFCYSMLHKVSRSFSLVIQQLNTELRNAVCVFYLVLRALDTVEDDTSIPTDEKVPILIAFHRHIYDTDWHYSCGTKEYKILMDQFHHVSAAFLELEKGYQEAIEEITRRMGAGMAKFICQEVETVDDYDEYCHYVAGLVGLGLSKLFLAAGSEVLTPDWEAISNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPREIWGKYADKLEDLKYEENTNKSVQCLNEMVTNALMHIEDCLKYMVSLRDPSIFRFCAIPQIMAIGTLALCYNNEQVFRGVVKLRRGLTAKVIDRTKTMADVYGAFYDFSCMLKTKVDKNDPNASKTLNRLEAVQKLCRDAGVLQNRKSYVNDKGQPNSVFIIMVVILLAIVFAYLRAN
What are the official names of this protein?
Squalene synthase 1, SQS 1, SS 1, FPP:FPP farnesyltransferase 1, Farnesyl-diphosphate farnesyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SECA_PSEA8
Sequence: MFAPLLKKLFGSKNERDVKRMAKAVQAINALEPQMVALSDEQLKAKTAEFQQRYAKGETLDQLLPEAFAVVREAGKRVMGMRHFDVQLIGGMTLHDGKIAEMRTGEGKTLVGTLPVYLNALSGKGVHVVTVNDYLARRDANWMRPLYEFLGLSVGVVTPFQPPEDKRAAYAADITYGTNNEFGFDYLRDNMAFSLDDKFQRELNFAVVDEVDSILIDEARTPLIISGQAEDSSELYIKINKLIPRLKRQVEEVEGKPTEEGHYSIDEKTRQVELNEQGHQFIEDLLSQNGLLGEGESLYSAHNLSLLTHVYAALRAHTLFHRNVEYIVQGDQILLIDEHTGRTMPGRRLSEGLHQAIEAKEGLPIQAESQTLASTTFQNYFRLYNKLAGMTGTADTEAFEFRQIYGLDVVVIPTHRPIARKDFNDLVYLTQEEKYAAIITDIKQCQALGRPILVGTASIESSEYVSKLLQEAGIEHKVLNAKYHEKEAEIIAQAGAPGSVTIATNMAGRGTDILLGGNWEVEVAALENPTEEQIAQIKAEWQKRHQQVIEAGGLHVIASERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDNLMRIFASDRVKNFMKALGMQSGEAIEHRMVTNAIEKAQRKVEGRNFDIRKQLLEFDDVANEQRKVIYHMRNTLLSAEDVGETIKEFREETLSATINQHIPPQSLPEQWDIEGLEAALYSDFAVRLPIQQWLDEDDKLYEETLRSKILEQIVAAYYEKEELAGAEALRAFEKQMLLRVLDDLWKDHLSTMDHLRHGIHLRGYAQKNPKQEYKRESFTLFQELLDSIKRDTIRVLSHVQVRREDPAEEEARLRREAEELAKRMQFQHAEAPSMEQAVAGEEEELPEGPAPVVPLEPVRNEQKIGRNEPCPCGSGKKYKHCHGQLD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PCKA_ECOHS
Sequence: MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEELAGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1047_ARCFU
Sequence: MIEMLIGIAFAGFILAIPYVYERVGGKLSLGKLSLGMPKLRSKKEVEEKIKEVDRELEEVVNAGVSINPKPAEEKVVPLDDANVEPDDNLLEEMETASEIKVEAPEPDEEKLPDIPDLPELNSDLDMDFEDLGQEIPLDADEQEEEEEEEEVEEVEFDEEDDLISSLAKEVETKEEEEIDLLRDLKGQKFSAEELEAELQEMIQRLKVLSGGSS
What are the official names of this protein?
Uncharacterized protein AF_1047.
Protein: RIMK_XANC5
Sequence: MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDAVIPRIGASVTRYATAVLRQLEFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASASRGVVEALRGLYANFIVQEFIGEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVTEATEQEQEVAVRSARALGLTVAGVDLIRSKRGPLVLEVNSTPGLEGVEGVCGVDVAAAIVQHLEQSVRRSAG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.