PharMolix/UniProtQA huggingface dataset:
Protein: DTD_STRS7
Sequence: MKIVIQRVKEASVSIDGEIAGAIDQGLLLLVGIGPDDQAEDIDYAVRKISHMRIFSDPEGKMNLSIQDIGGSVLSVSQFTLYADTKKGNRPAFTGAAKPAMASELYDTFNAQLEQLVPVQRGVFGADMQISLTNDGPVTIILDTKHR
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBP1B_WHEAT
Sequence: MAEASPRTETSTDDTDENLMLEPGNAALAVVSDSSDRSRDKNGDQKTMRRLAQNREAARKSRLRKKAYVQQLENSRLKLTQLEQELQRARQQGIFISSSADQSHSMSGNGALAFDTEYARWLEEHNRQVNELRAAVNAHAGDTELRSVVEKIMSHYDEIFKQKGNAAKADVFHVLSGMWKTPAERCFLWLGGFRPSELLKLLSTQLEPLTEQQLSGICNLQQSSQQAEDALSQGMEALQQSLAETLAGSIGSSGSGSTGNVANYMGQMAMAMGKLGTLENFLSQADNLRQQTLQQMQRILTTRQSARALLVISDYSSRLRALSSLWLARPKE
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'.  Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter.  Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription.  Binds to the hexamer motif 5'-ACGTCA-3' of histone gene promoters.
What are the official names of this protein?
Transcription factor HBP-1b(c38).
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYSH_KLEP7
Sequence: MSVLDLNALNALPKVERILALAETNAQLEKLDAEGRVAWALENLPGNYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAAESAAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELNAQTWFAGLRREQSGSRATLPVLAVQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_RICPR
Sequence: MTELKIKTEKVVKQLTKESLKSVLKIPKEKIDSVSKFYATGKRKNAIARVWLKVGKGKIVVNNKILNQYFPSETYVKTILQPFILTKTIDQYDVICTVKGGGISGQKGAILHGISKALDKSAPCFHAILRKGGLLTRDSRVVERKKYGQRKARKKTQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RR3_LACSA
Sequence: MGQKINPIGFRLGTTQGHHSLWFAQPKNYSEGLQEDKKIRTYIQNYVQKNMKTSSGVEGIARIEIQKRIDLIQIIIYMGFPKILIESRPRGIEELQMNLQKEFHSVNRKLNIAITRIEKPYGNPNILAEFIAGQLKNRVSFRKAMKKAIELTEQADTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDYCCYTVRTIYGVLGIKIWIFIDGE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SECB_PSEAE
Sequence: MTEQATNGAADEQQPQFSLQRIYLRDLSFESPKSPEIFRQEWNPSISLDLNTRQKQLDGDFYEVVLTVSVTVKNGEDTTAFIAEVQQAGIFLIKNLDPSSMSHTLGAFCPNILFPYAREALDNLVVRGSFPALMLSPVNFDALYAQEIARMQASGEIPTPSVQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAB3_XENLA
Sequence: MAQSSPQLDIQVLNDLQQRFPEIPRDVVSQCMLQNNSNLDACYRALTQESCKYLYMDYHNLDETRMNSNLLHINLGIHPSSTYHTGDGAQVNGRPLVHSSSDGHIDPQRSPGKLLCLVPEPQSAPAVVAQNYNQFFLNDQNRNSPTPPPQPVQQPGVGTSAMQASLPTYMHVPRYSANPITVTVSPSGHNVPRALQIVPQVQNNPYGTPIYIRHPSQNSPGRQTQQNTAWPPSPQAVLPHYNPCPPYPQSFQPTQYSPKQPQIPQSAFRSPPTSQCTSPYSSPQHQVQTNQLSHQTSHVFLPPSPSTVSPHLYQQAPPPYPKQSSLGYLPYGPGLNKGPMNKIEITVESQQRPGPTLNRSPSPINNQSAQRSQQHPVYVSNARSGSPSRGIPTQPKASYSGSPLFITYSQPPTTTGSPTPSSRVVMSPSNPTVFKITVGRAPTENLLNIVDQEQHPSTPEPIQPISLLPVSGGDKGIHKYHRSSSSGSDDYAYTQALLLHQRARMERLAKELKHEKEELERLKAEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRGLNRQLQINVDCTQKEIDLLQSRGMAKLDVKAMSNFYDNLSPGPAVPPNTCKKESSETTSGERKARRISVTSKIKSDPPDLQAPSSLDIGPWQRASPRPGRDEDFEGSPWNCNSCTFLNHPALNRCEQCEMPRFT
What is the function of this protein?
May play a role in signaling pathway.
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 homolog.
Protein: TYRO_STRAT
Sequence: MTVRKNQASLTAEEKRRFVAALLELKRTGRYDAFVTTHNAFILGDTDNGERTGHRSPSFLPWHRRFLLEFERALQSVDASVALPYWDWSADRSTRSSLWAPDFLGGTGRSRDGQVMDGPFAASAGNWPINVRVDGRTFLRRALGAGVSELPTRAEVDSVLAMATYDMAPWNSGSDGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYIDKLWAEWQRRHPSSPYLPGGGTPNVVDLNETMKPWNDTTPAALLDHTRHYTFDV
What is the function of this protein?
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.
What are the official names of this protein?
Tyrosinase, Monophenol monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
Protein: XYNA_ASPKW
Sequence: MVQIKAAALAMLFASHVLSEPIEPRQASVSIDTKFKAHGKKYLGNIGDQYTLTKNSKTPAIIKADFGALTPENSMKWDATEPSRGQFSFSGSDYLVNFAQSNNKLIRGHTLVWHSQLPSWVQAITDKNTLIEVMKNHITTVMQHYKGKIYAWDVVNEIFNEDGSLRDSVFYKVIGEDYVRIAFETARAADPNAKLYINDYNLDSASYPKLAGMVSHVKKWIEAGIPIDGIGSQTHLSAGGGAGISGALNALAGAGTKEIAVTELDIAGASSTDYVEVVEACLDQPKCIGITVWGVADPDSWRSSSTPLLFDSNYNPKPAYTAIANAL
What are the official names of this protein?
Endo-1,4-beta-xylanase A, Xylanase A, 1,4-beta-D-xylan xylanohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ECDE_ASPRU
Sequence: MKLNIFASAILLCTSAFPVAASRLDKPYTEVYRPQYHFSPKENWMNDPNGLVYDTDEGIYHIYFQYNPGGTTWGAMSWGHATSRDLMHWTEHPVALRARGFPDNITEMFFSGTVVVDESNTSGFGRKGKVPWVAIYTSYYPMEQVLPSGKRVRKDQQAQSIAYSLDKGMTWTTYDAANPVIAEPPAPYHDQHLEFRDPSVFWHVETSRWVAVVSLAKLHKILIYTSQDLKQWDWVSEFGPANAVGGVWECPSIFPLTLDGSQQDKWVLMLGLNPGGPPGTIGSGTQYIVGDFNGTTFTADADSIYDGSGPNDGMIFEDFEGDESLAARGWATTGDFINASPVRGTLSGQNAVTGFQGQQLFNTFLNGDATTGAITSAPFDITYKYINFLVGGGNDINETAIRLNVNGKTVHASTGSNDEHLTWQSWDVSSLKGQRAVIEIIDNASDGWGHINVDQICFSNTRATNQIANWLDWGPDFYAALSFNGLDRDQRTILAWMNNWQYGAAIPTDPWRSAMTVPRRLALKTIDGKPSLVQQPAGRWRTSGNHGREFSFRAVDGVRPLGRLGKALDIELTFSSNMSPSNGLGEFGVSIAATKGYQYGTRVGYDFATQQVFVDRSRSGDVSFDATFPGVYHAPLSNSANGTISLRILLDWSSVEVFGAHGEATITSQIFPGPDAVYGQLFSSGGQTRDVSLQVREIQSTWH
What are the official names of this protein?
Putative glycosyl hydrolase ecdE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: AEP1_YEAS8
Sequence: MITTVQEISKWRNLCFIRMQSRKWYPVLKKTPLVADGRKIIKHADKVPHPGEIIHPFYQPTAIEQFTACATEYNPSLLDGKKIAPSLIKHPVSLKTILVDSKLKFDDIRGVNRWLMEFVARRQHQRNIVLTPASKSVRSFHVLHLSSTDIAKLRGLENVLSEIENTNDLQSRVESVNNELQNIFDRDSKQTRLFCEDILAYLIKNYGNSTENLILLINVTEMQLFSRLDQMKAMNIILYHILCKVEANENPPYSPTLVTALENLLAAINNRFFPGRCENSLHPIVIEQLLSYFIKTGNLNESKNFLGHLIKKGILPEATIINRYLEAIDVHFDKSTKIFDIRSKFAFIADLAPIIENYGTIDLFKFLIPMCRHFDELCSLLNIIRKSNNAKQAVDSTLPIFIKKVLTFTKDPMINSGNLSTVFNIVSPIYGQNVPSEFVEKFILSFALQGNYTMMAHMIDTYKIKLSHKYQLQIIRALKNSERNHALKNTGAVGYNKEFKKYFIEKYLNCTEREALRP
What is the function of this protein?
Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.
What are the official names of this protein?
ATPase expression protein 1, mitochondrial, Nuclear control of ATPase messenger RNA expression protein 1.
What is the protein family that this protein belongs to?
Belongs to the AEP1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: OBG_STAA8
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENDA_SULIA
Sequence: MVKALLVGSKVLIPNVDESRYIYSNGFYGKAIGISKPKGPKDIIRPLELSLIESVYLAKKGLIKVIDKNGEVLEYEKLYEYSSKIINKFDIMYRVYEDLREKGFIVRSGVKYGADFAVYTLGPGLEHAPYVVIAVDIDEEITPHELLSFGRVSHSTRKRLVLALVDRKSESVRYIMFKWVKM
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: BDBC_HALH5
Sequence: MSKKVENLMLGSWLTALTAMLGSLYFSEIRMYEPCTLCWYQRIIMYPLVLILFIGYLKRDVNVALYSLWFSLIGMFTSLYHYSIQKLPFLTDAAPACGRVPCTGQYINWFGFVTIPFLAFTAFVIIFICSLLIIREK
What is the function of this protein?
Required for disulfide bond formation in some proteins.
What are the official names of this protein?
Probable disulfide formation protein C, Disulfide oxidoreductase C, Thiol-disulfide oxidoreductase C.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. BdbC subfamily.
Protein: Y2166_AERS4
Sequence: MLCAVYKSRKKAETYLFVERREDFSRVPEVLMSTFGRPELVLMTKLDPAKPLGIASTSRVIEALGSQGFYLQVPPPPENLLEQHKAQLKVSR
What are the official names of this protein?
YcgL domain-containing protein ASA_2166.
Protein: ASSY_HAES1
Sequence: MSNTILQHLPIGQKVGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYNAIPRKAMEYGAEKARLIDCRNQLAHEGIAAIQCGAFHISTGGVTYFNTTPLGRAVTGTMLVSAMKEDDVNIWGDGSTFKGNDIERFYRYGLLTNPSLRIYKPWLDNQFIDELGGRQEMSEFLIANGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSGIRIVKPIMGVAFWRDDVTVKAEEVTVGFEDGVPVTLNGQSFSSAVELFLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTAIHNEDTIEQYRINGLRLGRLLYQGRWFDPQALMLRETAQRWVARAVTGEVTLELRRGNDYSILNTVSPNMTYHPERLSMEKVENAPFDPSDRIGQLTMRNLDITDTRDKLGIYTHTGLLTVGKDSMLPQLDKK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1125_HAEI8
Sequence: MENNDELMPREKLLAFGAKALSDYELLAIFLRTGIKDCPVMSLSKNVLTHFGSLHALLSADKKAFCSVKGLGITQFIQLQAITEMTKRYLKQEMLSTPIINDLETVKLFLLTELQHEEREVFMVLFLDNQHRLIKKERLFLGTINVSAVYPREIIKEALYCNAAALILAHNHPSGITEPSYSDQLITKKIQDAAELMEIRVLDHLIVGKSDCYSFAENCLL
What are the official names of this protein?
UPF0758 protein NTHI1125.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: GUAAB_METB6
Sequence: MVKTEKFIQKSVEEIQKEAGNEKVVMALSGGVDSSVCASLAARAIGDRLIPIYIDTGLMRKGETERIKAVFGNIRLQVVDAGDEFVAALAGITDPEKKRKAIGERFIRVFEREAKKSGATCLLQGTIYPDRIESEGGIKSHHNVGGMPEHTAFKKVIEPIRDLYKDEVREVAGALGLPPEIQHRMPFPGPGLAVRILGEVTKEKVAVIREANWIAESEIVEKYRPWQCFAALIGLGTGVKGDNRIHGWIVAVRAVNSRDGMTADPLEIPFADLVRIGSRITAEIPSVARVVYDITPKPPATIEYE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: YP06_CSVMV
Sequence: MKGIKCLSITCFLSDNSIIRVVLIRRMLKILLFSLLVLIILCFIDPILFYFICL
What are the official names of this protein?
Uncharacterized 6 kDa protein.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: Y347_RICBR
Sequence: MSKNNYYPYPPTLGKVFLFKRGPEIVSMESSETIQPADKLESILNSTSTITAELLFNTFDIPGISSKTDKLKLLFQKAFEQGINPNIQDSSGNTLLLYACQSSLVEVVQFLLKKGANPNISNNSDNTPLSKIISNRFIDKTEIYIAKLLLQNGALTELKDFVGFTPIQSATQYGHTEIVKSLIQNGADINVIASIETNSYYSGKSLVESVPSNKPELKALLTLTKACKDNNFSIVDNTITAKDIVEFIDWQLSITPENSRFFDKHLSELDNLKNFLETKELVSNETIQKINEHITSYSTTEISSPDVTPSFINEAEHQEYNLAGETDKSAPETA
What are the official names of this protein?
Putative ankyrin repeat protein RBE_0347.
Protein: Z280A_HUMAN
Sequence: MGDIFLCKKVESPKKNLRESKQREEDDEDPDLIYVGVEHVHRDAEVLFVGMISNSKPVVSNILNRVTPGSNSRRKKGHFRQYPAHVSQPANHVTSMAKAIMPVSLSEGRSTDSPVTMKSSSEPGYKMSSPQVVSPSSSDSLPPGTQCLVGAMVSGGGRNESSPDSKRLSTSDINSRDSKRVKLRDGIPGVPSLAVVPSDMSSTISTNTPSQGICNSSNHVQNGVTFPWPDANGKAHFNLTDPERASESALAMTDISSLASQNKTFDPKKENPIVLLSDFYYGQHKGDGQPEQKTHTTFKCLSCVKVLKNIKFMNHMKHHLEFEKQRNDSWEDHTTCQHCHRQFPTPFQLQCHIDSVHIAMGPSAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSSVFADVETHFRTCHENTKNLLCLFCLKLFKTAIPYMNHCWRHSRRRVLQCSKCRLQFLTLKEEIEHKTKDHQTFKKPEQLQGLPSETKVIIQTSVQPGSSGMASVIVSNTDPQSSPVKTKKKTAMNTRDSRLPCSKDSS
What is the function of this protein?
May function as a transcription factor.
What are the official names of this protein?
Zinc finger protein 280A, 3'OY11.1, Suppressor of hairy wing homolog 1, Zinc finger protein 636.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUNA_MYCLE
Sequence: MTYTLLDPDELARRAAQVIGERTGILKHDVAVVLGSGWSSAVAALGSSRAVFPQAELPGFITPNAAGHTGELLSVRIGAHRVLVLAGRIHPYEGHDLRHVVHPVRTACAAGARIIVLTNAAGGLRADMAVGQLVLISDHLNLTTRSPLVGTHFVDLTNAYTTRLRKLASDTDPTLTEGVYAAQPGPHYETPAEIRMLRMLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGKPLNHAEVLAAGTASANRIGSLLADIIARF
What is the function of this protein?
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.  Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.
What are the official names of this protein?
Purine nucleoside phosphorylase, PNP, Pu-NPase, Inosine phosphorylase, Inosine-guanosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
Protein: Y118_CHLMU
Sequence: MLACHHNCKHFGICGGCSSPQTEYELSLKAKELALHNLFSPLIPSQKILPVIPCSPILRGRNKMEFSFYQTVDGEKTLGFISPSKPKKGIPITECLMIDERAIDILNYTRSWWATHPELSAYYPPLNKGSLCTLTVRIGNVSNDFMIILTTSGREEFAVPLSVIQEWQKTLLDSGLPITSIFWEEKLSARNSPTTFRTTHLYGEQFLKQQLSIEGRSNIFHVRPRSFFQPQSRQAEKIIQTIKDFISPTGEETLLDLYCGAGTIGISLSPYVKKIIGVELVPDAVASAQENIQLNSANMEVFLEDAKQFCRRHEHLPPLDIVVIDPPRCGMQNKALKYLLRMSPKKIIYVSCNPLTQISECSILVEHGYQLQRMQPIDQFPHTHHLENVVLLERLSF
What are the official names of this protein?
Uncharacterized RNA methyltransferase TC_0118.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: KLH20_BOVIN
Sequence: MEGKPMRRCTNIRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport.  The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis.  The BCR(KLHL20) E3 ubiquitin ligase complex also specifically mediates 'Lys-33'-linked ubiquitination.  Involved in anterograde Golgi to endosome transport by mediating 'Lys-33'-linked ubiquitination of CORO7, promoting interaction between CORO7 and EPS15, thereby facilitating actin polymerization and post-Golgi trafficking.  Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.  The BCR(KLHL20) E3 ubiquitin ligase complex acts as a regulator of neurite outgrowth by mediating ubiquitination and degradation of PDZ-RhoGEF/ARHGEF11 (By similarity).
What are the official names of this protein?
Kelch-like protein 20.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Golgi apparatus, trans-Golgi network. Cell projection, axon. Cell projection, dendrite. Note=Localizes in the perinuclear region in normal conditions. Following IFN-alpha or IFN-gamma treatment, it is relocalized and sequestrated to the PML nuclear bodies, preventing DAPK1 ubiquitination (By similarity).
Protein: EM13_ECHMU
Sequence: MIQERADIEKAYASNLRKFAARLEMFLRTGVEYGTATNILSGLAKEAEDNAELHSNIAAGLINPVQLGIKNWQRENFHKSSISTSIKEVKNFDSEFENAQKTWYKHYKNVNRCKKEYFHACKTVRSLQVQVQNAKNEPFGTPEQLRKIEDKLRKGIMEEEKTRKAYEEALSSLSDVTPRYIEDMTQVFNKAQAFERERIIYFKEQALQMQEVLDISAKPNLSQIFVGLRETVAKVDADADLKKWSLAYGVDMAPNFPVFQEYSPEMSALGKKGRSALADGSSGGVTLTSLKTITSPDRGGPIPGTTDSGSNISTSPVHTTAYGSNSYDHGSEGATPSDYTSSVNGAAAAISKEKQRVEDTPPYPDFVDDGRPGVPIRALYDYVGVEADELSFNSGDLFEKLEDEDEQGWCKGRKDGRVGLYPRQLR
What are the official names of this protein?
Antigen EM13.
Protein: GDL49_ARATH
Sequence: METLFHTLLRLLLFVAISHTLSPLAGSFRISNDFPAVFNFGDSNSDTGELSSGLGFLPQPSYEITFFRSPTSGRFCNGRLIVDFLMEAIDRPYLRPYLDSISRQTYRRGCNFAAAASTIQKANAASYSPFGFGVQVSQFITFKSKVLQLIQQDEELQRYLPSEYFFSNGLYMFDIGQNDIAGAFYTKTVDQVLALVPIILDIFQDGIKRLYAEGARNYWIHNTGPLGCLAQVVSIFGEDKSKLDEFGCVSDHNQAAKLFNLQLHGLFKKLPQQYPNSRFTYVDIFSIKSDLILNHSKYGFDHSIMVCCGTGGPPLNYDDQVGCGKTARSNGTIITAKPCYDSSKYVNWDGIHYTEAANRFVALHILTGKYSETASSLNL
What are the official names of this protein?
GDSL esterase/lipase At3g05180, Extracellular lipase At3g05180.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARMD4_ARMGA
Sequence: MASTSVSQGRVALVTGAGQGIGRAIALRLASDGFDVALNDLQANEANLVSALAAIEAVGRKGCYIFADVSQETEVEQMISKVVEELGGLDVMVCNAGISLMKSFFDTTAEDFDRITSVNLRGTFLCYKHAGKQMVTQGKGGRIIGACSGTGKKGQPLFSAYAASKFGIRGLTQVAALEFGPHGISVNAFAPGPVKTPMYDHFETIIGTPKGVLEQELNKTAALGRIALPEDVAVVVSFLASKEASLITGQTINVDGGIVFD
What is the function of this protein?
Short-chain dehydrogenase/reductase, part of the gene cluster that mediates the biosynthesis of melleolides, a range of antifungal and phytotoxic polyketide derivatives composed of an orsellinic acid (OA) moiety esterified to various sesquiterpene alcohols (Probable).  The first step in melleolides biosynthesis is performed by the delta(6)-protoilludene synthase PRO1 which catalyzes the cyclization of farnesyl diphosphate to protoilludene (PubMed:21148562).  The orsellinic acid synthase armB produces OA by condensing acetyl-CoA with 3 malonyl-CoA units in a three-round chain elongation reaction folowed by a C2-C7 ring closure (By similarity).  ArmB further catalyzes the trans-esterification of OA to the various sesquiterpene alcohols resulting from the hydroxylation of protoilludene (By similarity).  The melleolides cluster also includes 5 cytochrome P450 monooxygenases, 4 NAD(+)-dependent oxidoreductases, one flavin-dependent oxidoreductase, and one O-methyltransferase (By similarity).  The cytochrome P450 monooxygenases may be involved in protoilludene hydroxylation to elaborate melleolides with multiple alcohol groups, such as melleolide D, which carries alcohol functionalities at C-4, C-5, C-10, and C-13 (By similarity).  The role of the NAD(+)-dependent enzymes remains unknown (By similarity).  Numerous melleolides, including arnamial, show 5'-O-methylation of the aromatic moiety which may be catalyzed by the methyltransferase encoded in the cluster (By similarity).  The flavin-dependent oxidoreductase might represent the dehydrogenase yielding the aldehyde in position 1 of arnamial and other melleolides (By similarity).  Finally, several halogenase localized outside of the cluster, are able to catalyze the transfer of a single chlorine atom to the melleolide backbone, resulting in a 6'-chloromelleolide product (By similarity).
What are the official names of this protein?
Short-chain dehydrogenase/reductase ARMGADRAFT_1018421, Melleolide biosynthesis cluster protein ARMGADRAFT_1018421.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RECF_SHEB2
Sequence: MSLTRLNIEAFRNIQSAQLIPAPGINLIYGQNGSGKTSILEAIYFLGMGRSFRSHLSQRVINNDDDKLTLFATLNLARGDSKIGLRRFRSGETEVRIDGEKVKRLSTLAETLPIQVITPESFSLLFEGPKSRRQFIDWGAFHADPQFYGAWTNVRRVLKQRNQLLRNGSSYSNIQFWDQEFVRYAEQVTEIRNHYVDSLNELLKGIIGEFLPSVDVKVSFTRGWDSKTDFAELLENQYSRDLATGHTVSGPHKADLRLRVGTLPAQDALSRGQLKLLVCALRIAQGKLLKQQIDKHSIYLVDDLPSELDAQHRQLLLKQLTDTGAQVFVTAIDPAAIVDSLHTPPSRMFHVEQGRVTVIE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANR_ECO7I
Sequence: MGLMNAFDSQTEDSSPVIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.