PharMolix/UniProtQA huggingface dataset:
Protein: TTRA_ARCFU
Sequence: MQLSRRDFIKGLVAVGSASVFLAGYSETVDRLVKPRYTEVKPDSVGRIVHSACLGCNVRCGIRVNVVQRGGMEVVERISGNPYHVYNRYVSKEKQSRRYEPLPYNTPITEGLKYSGTLCARGEDGIHYLYDPYRIIVPLKRAGPRGSGKFKPITWEQLINEVVNGGVIEETGERLPGLKELFAYGILSEAGFDANAVLSEMKKDVDAIMEIAKDDTKSYGELTEAINNFKAKWSAKLGEKGLKLEDILIDPDRPDLGTKANQLVYMRGRGQGHADYFYQRWTYAFGSVNWLRHTSSCQLGYYAGNKIWSGYHDVQADPIGAKLLLMVGAQMGRLHPGATGQGLIVERAAEGELKVYYVNPTAPRTTANGNIVWVPIRPGTDAAFAMALLRVMFERGYYDAEFLSYANTDAARKAGYPLNTNASWLVIWEGDRKGEFLKGEDIGLGSDNPVVYAGSFVTNDSVEKAEIFFDGYVETKEGKRRVKSALQILKEECFSRSVEEWCEICGVDVAVIYEIAEEIRKAMPNCGTIVHRGAGMHTNGEYNVWALRCIDMLIGNIHRKGGLMTRASHTNYNKELYYVDKSKFGEPVRWGPPIDRHKVAYEDSLEYWMKKKRGENPYPAKRPWYPLTPEESYTEMFAGIAEEYPYPIKALIMYYANPVLSANFGVKFIEVLKDTSKLPLFIAITTSINETFLYADYIVPDTMYLETGTMGINYLYATSASVTLAEYWRSPAVMPMTQLVGTCPNGHPKYASMWEFLIDIALKLKMPGYGKGAVKGVGAYDGQKFDLYCAWEYIMYVFANAAMDAKKRGLIPETVSDEEVDFVEKNYPIARFKDIVPNEWRYVAYGLARGGVFTRYEDSFDERGYSKRKPWTDTVYFWSEKLAKARNSVTGEKFYGGPKYLPPATYAPLGTERRFYGTPLREIYPESQYPFLVVPPGSPLFTKHRSMFYYWLKQVMPENFAVINPEDAEKLGIESGDVIKIVTPTGELEVVAAVEPTVVKGTIAIPVGMGRWADSAVKKPAYFRLNDGSVAALVSELPDGASLPSDAVNPVKQLDETKKRILFTKSDRRYYDDLGIDSWRFSGVTPNVVACVDTSLDNWPLLSWIGAAQVYFFIPAKVEKTGKRKKFEMPNVWW
What is the function of this protein?
Part of a membrane-bound tetrathionate reductase that catalyzes the reduction of tetrathionate to thiosulfate.  TtrA is the catalytic subunit (By similarity).
What are the official names of this protein?
Tetrathionate reductase subunit A, Tetrathionate reductase molybdenum subunit.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARNA_ECOBW
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPDVIFSFYYRHLIYDEILQLAPAGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: DHX15_STRPU
Sequence: IKYMTDGMLLREGMTDPLLERYGVILLDEAHERTVATDILMGLLKEVEKQRSDLKLVVMSATLDAGKFQHYFDNAPLMTVPGRTHPVEIFYTPEPERDYLEAAIRTVVQIHMCEEVEGDVLLFLTGQEEIEEACKRIKREVDNLGPEVGDLKTIPLYSTLPPAMQQRIFEHAPPNKANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRVGRAGRTRPGKCFRLYTEKAYDSEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLGALDDSGDLTRLGSMMAEFPLDPQLAKMVIASTDYSCSNEILSVTAMLSVPQCFLRPNEAKKLADEAKMRFAHIDGDHLTLLNVYHAFKQNNEDPQWCYDNFIQYRSLKSADSVRQQLARIMDRFALQRTSTNFNSKDYYL
What is the function of this protein?
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.
What are the official names of this protein?
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL10_NITMU
Sequence: MSLNLDEKKAVVAEVSAQVAKAQAIIIAEYRGLGVGHMTQLRAKARQSGIYFRVLKNSLARRAVSDTPFSGLSEHMVGPLAYGIGSDPVAAAKVLHEFSKGNDKLVIKAGAMANHVISSSEIASLASLPSREELLAKLLGTMQAPVANFVRTLNEVPARFVRGLAAVRDQKESA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: APD_DOLMA
Sequence: GKPRPQQVPPRPPHPRL
What is the function of this protein?
Antimicrobial peptide active against many Gram-negative enterobacterial and plant-associated bacterial species.  Not active against other bacterial species like H. pylori, P. mirabilis, B. pertussis or N. gonorrhoeae.
What are the official names of this protein?
Apidaecin +.
What is the protein family that this protein belongs to?
Belongs to the apidaecin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_RHOBA
Sequence: MSGTCVIGLQWGDEAKGKLVDLLAPRFDWVVRYQGGANAGHTVVAGDETYKLHHIPSGILHSDVQNVITPGVVINPTTMLQEIDGLQARGIDVFENLKVSERAHLVMPWHMIEDATINATAVRGESIGTTNRGIGPCYRDKVGRTHAIRMIDLIEGSRDERIATVAGQKQVLLKNLGASEEELDSIAPEKMVALAASWAERLAPMIADTTDMVLDAAEANQKMLFEGAQGALLDIDHGTYPFVTSSNSSGVGVCAGAGVPPKWINQVLGVCKAYSTRVGGGPFPSELEDETGEKIRKLGNEFGTTTGRPRRCGWFDAVAVRYTARLSGVTRLALMMMDVLAHFDELKVCVAYELDGKEIHRVPAHAEQLRRCKPIYETIQGWNTPVDDARSVDDFPPLAMAYVKRIEELVGIPVGVLSVGPDRAQTIFTEESKVMGL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_ECO5E
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RL6_GLUDA
Sequence: MSRVGKYPVEVPSGVQVSIVDGIFVAKGKLGELKLPLSQHIEAEIADNKVSVRPVGTAAPARMMWGTTRALVASMVKGVSEGFSKTLEVTGTGYRAAVQGSNLVMNLGYSHDIVYAIPAGIKITTPRPTAIVVEGVDKQRVGQVALDIRSFRKPEPYKGKGVRYDTETIRRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: GCH1L_LACLA
Sequence: MKISDFMLEYEKFCPKELAVEGDPVGLQVGNPNDELTKVLVTLDIREQTVAEAKALGVNLIIAKHPLIFRPLSALTSMNDQEKLVLDLARAGIAVYTSHTNIDVVTGGLNDYFSQLLGMTDIEVLDDEEGLGRVGNIELTELSVLTEKVKASFGLDRLRLITYDHNLTQKIGRIAICGGSGGKLWPKALEKKADIYITGDIYYHVGHDMLSAGLLGIDPGHYIEHAFIRLVADKLRSFDMGVKIYESQEKTNPFYDI
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: GLYA_HALS3
Sequence: MAYDEVREVDPEVADALTGERHRQNDTLAMIASENHVSEAVMEAQSSELTNKYAEGYPGSRYYGGCEYADDVEELAVARAKELFGADHVNVQPHSGSSANMGVYFATLAPGDKILSLDLTHGGHLSHGHPANFAGQLYEVEQYEVDAETGRLDYEALREHADAFEPDMIVSGFSAYPREVEWERIQAAADAVGALHMADIAHITGLVAAGEHASPVGVADFVTGSTHKTIRAGRGGIVMCDEAFADDIDSAVFPGAQGGPLMHNIAGKAVGFNEALDPAFEEYAAQVVENAAVLGERLQEHGFSLVSGGTDTHLVLVDLRESHPDISGGDVEGELEDVGIVLNANTVPDETRSAFDPSGIRIGTPALTTRGFDADAMETVADCIARVIDNLGDESVYADVADTVADLCEQYPQYE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPI1_SOLTU
Sequence: MKSINILSFLLLSSTLSLVAFARSFTSENPIVLPTTCHDDDNLVLPEVYDQDGNPLRIGERYIINNPLLGAGAVYLYNIGNLQCPNAVLQHMSIPQFLGEGTPVVFVRKSESDYGDVVRVMTVVYIKFFVKTTKLCVDQTVWKVNDEQLVVTGGKVGNENDIFKIMKTDLVTPGGSKYVYKLLHCPSHLGCKNIGGNFKNGYPRLVTVDDDKDFIPFVFIKA
What is the function of this protein?
Potent inhibitor of cathepsin l (cysteine protease).  Does not inhibit trypsin or chymotrypsin (serine proteases).  May protect the plant by inhibiting proteases of invading organisms.
What are the official names of this protein?
Cysteine protease inhibitor 1, P340, P34021, PCPI 8.3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Vacuole.
Protein: XERC_NEIM0
Sequence: MVLDGFAAHFDAYLENIVREGKSEHTVAAYRRDLEELFALLAQMPSEAEGGVPQGLSRRDFTAALRRLSQRGLNARTLARKLSSWRQYCVWLVERGLLHTDPTADIKPPKQPERVPKALPQEWLNRMLDLPVDGGDPLAVRDHALFELMYGSGLRVSEIHGLNADDVYLDEAWVHVTGKGRKQRQVPLTGKSVEALKNYLPLRQTASDGKALFTGRNGTRLSQRQIQKRLAQWAAQNGDGRHVSPHMMRHSYAGHLLQASRDIRAVQELLGHSSLSTTQIYTKLDFDHIARLYDEAHPRAKRQDE
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORFC2_PICV
Sequence: MRVPVGHTQQLTEGQPAVEVINDDYFLVVVPVPPFTLHLVEFTSGVVSCPTALPATGRARDDDDFRFEVTGLLTNQQLQVAQATPIFDVYLTEVSRDLGHCSSGFHRGNSLAEIAPVSLRRNAQGK
What are the official names of this protein?
Uncharacterized protein ORFC2.
Protein: HIS4_STRMK
Sequence: MSFIVYPALDIRDGRVVRLRQGDYAQETSYGDDALPRAQALAAQGAQWMHLVDLDAARAGGYTLAPLLASIRAQTPLQVQTGGGVRGRDDVARILDAGAGRVVVGSLAVRRPDEVVGWLEEFGAERITIALDARQDAQGQWQLPVHGWTENAGVTLDVLAQRYARAGMRHLLCTDIARDGMLAGPNISLYQHLSALLPGVAVQASGGIRDVADVAEARRAGCGGAILGKALLEQRMDLAEALAC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_ACTP2
Sequence: MTLKIGIVGAGGRMGRNLITAVQNAEGVELGAAFERKGSSLVGADAGEVAGIGATGVKISDDLNQNTNFDVLIDFTRPEGTLEHIKFCVANGKKMVIGTTGFDDAGKQAIQTAAEQISIVFASNYSVGVNLVFKLLEKAAKVMGDYCDIEVIEAHHRHKVDAPSGTALSMGEHIAKTLGRDLKTHGVFAREGITGERKRDEIGFATIRAGDVVGEHSVWFADEGERVEIAHKASSRMTFANGAVRAAKWLNTKQNGLFDMTDVLDLNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM5_SCHPO
Sequence: MSMTILPLELIDKCIGSNLWVIMKSEREFAGTLVGFDDYVNIVLKDVTEYDTVTGVTEKHSEMLLNGNGMCMLIPGGKPE
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner.  LSm5 is required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm5.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPL_ECOL6
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRM1_COPC7
Sequence: MSFLTTPPNEHTTLTSYLQLPHLLSLTWLAYPILSLIFVAFRLQASLASSEDAISSAKSNLLASCKAAEEAATSTASLPRYMAIATNQQVADAVNATLRGARAALILTLTVMEAIINFIIDLYRSIFLCFLELVVRGGIAILVGAVEEINNVLATVTSGLRTQIQASVGTLNNALRETIEGINRINPFGDIPVPTFDPPNLDGLDNVSLPDSFQESLLRLNDTIPTVSTIKEKLQDIIGTPFELVKRDINDTFAAVSFSADTLPVPEQNKVSFCSDLDLSVVDDVGNDIVKSAKIGIVILLVIALVLIGLNCLFTWYKWRCMQAHLEYTRQAWNTDPTMQTKGSISATPQIALSNHNLMVLQANSEHPLVTRITNQLSQKLRLSPRTHTHMQWFFNYIFHPPAAACLLIGVFGLLLIEIQLLAMGPLVNKYQEQAAETTKDFSLLIANSINESMLNQSTIYAAEINGRVDSVQTTINDGLFGWVDGTIVPLNTTINEFYDDIQNAVQTVFGGTILETAATEFIRCLIGSKVDAVENALTFLHENLRVDMPRVNDTALMLSPESVNEASAPIAAAAMGGGTDDDQGLIGRLVNSYADSLRKERVTFGIFLALWGVVVLMGLFVLFWHSTGKPLLEKRRRRKYEKSKGMLPEGGFVVPYRDGSAPPSRDEKNLGGGGNGGVGLAMTGDELPQFTPLPSPRRSAFKPFWNPAKPDASGEAKDVEKEPSPMAQVAADEVSKLKAFRLKLMGKSTESLDADSKASDNPPGLFGKVKGVFGKKDADQAPDYWTSYNASSDTVNANTARPNIRVIVDTDQDREDTYGNSFRHSADIEGADIYTPPPNSRWSTSPGPTKTSWNLKKLTLLSPKSSNNKKLPAVSGSSSIGPIPPSMSAAASGLKRQPSVPTDIGASFDDPFMASVSVPRKPSPIVPGIYPVPLHAAAPAINNNPYQRAPSPPKRFVAPYLNDPSALSRNTSGSSASKTHRRSSSHPAAVWRVTNAASTDRLTASPMSSQVSLPARMLTSENPFITPFDDEHRVEVVNPSRGEVRKSMAVNPFSNAAAVAI
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein PRM1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL9_SHESR
Sequence: MNVILLDKIANLGNLGDQVAVKAGYARNYLLPQGKAVVANESNVKVFEARRAELEAKLAADLAAANQRAEKIAALEAVVIASKAGDEGKLFGSVGTRDIADAVTAAGVELAKAEVRLPLGALRTTGDFEVEVQLHTEVKAVVKVSVVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SEM2A_CAEBR
Sequence: MKAWILLLVLTRCSWGLISADNTFSDRTIGEFRELLINTKDGALFAGSEGAIFRLWAYNINDTGENVFSKKQLILSETEESECCSTASDEKLCRPSTRFLAFTNNKDSIYVCSSVGMRPEIRVLDSISLQDQQEPRTEIGICVVDPTFNSTAVVVDNGNPEDASSVYSGIRTGMGGENHLIYRPPLTKNGKQLHASIRTIYSDNKWLNEPQFVGSFDVGQHVLFFFREIAHDNSFGERIIHSRVARVCKKDIGGRNVLRQVWTSFVKARLNCSVSANFPFYFDHIQSVKRVDKHGETFFYATFSTSETAFTSSAICMFQLSSINHLLDTGLLMEETANGQFAVTADEIPAHRPGTCSSNSHSISDTDLHFAKTHLLVSDSISGGTPILPLRDHVYTQILVDQLNNQNVIFAFDSSQQKMWKISHWKEGNEWKWNLIETQTLKTSGFRINDVALLPGEFFFATSKAGVHQFSVARCQELPSCALCSMDPYCSWNAVNSKCALKTKTNEKSVGWISSSWAGRISPECSAVEKLQVKDVYLGDGFKIQGARGGTWQKDGRDLEESQRHVATSQGELVILNVDVEDAGTYECTRNGVILMRARVVVHENCARPTSVAEYRSCQREWCKKADAYKAALNIWSDSNKKNVQCKANGPSINGL
What is the function of this protein?
Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis.  In early embryonic development, required for proper ventral closure of the epidermis.  During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays.  Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129.  Involved in axon guidance.  Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus axon guidance and/or fasciculation of DD/VD neurons.
What are the official names of this protein?
Semaphorin-2A, Sema-2a, Male abnormal protein 20.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATOH1_HUMAN
Sequence: MSRLLHAEEWAEVKELGDHHRQPQPHHLPQPPPPPQPPATLQAREHPVYPPELSLLDSTDPRAWLAPTLQGICTARAAQYLLHSPELGASEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSGGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQASGGSQRPTPPGSCRTRFSAPASAGGYSVQLDALHFSTFEDSALTAMMAQKNLSPSLPGSILQPVQEENSKTSPRSHRSDGEFSPHSHYSDSDEAS
What is the function of this protein?
Transcriptional regulator.  Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1.  Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).
What are the official names of this protein?
Transcription factor ATOH1, Atonal bHLH transcription factor 1, Class A basic helix-loop-helix protein 14, bHLHa14, Helix-loop-helix protein hATH-1, hATH1, Protein atonal homolog 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: KBRS1_DANRE
Sequence: MGKGCKVVVCGMASVGKTAILEQLLYGSHTVGAETSDTQEDIYVASVETDRGVREQLRLYDTRGLREGLDLPKHFFSVADGFVLVYSVDCLESFKKVEVLKKEIDRSRDKKEVMVMVLGNKCELRERRQVDQDTAQQWARGEKVKLWEVTVTDRSTLIEPFTSLTSRLTQPQSKSAFPLPGRKSKGTPSNDI
What is the function of this protein?
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation.
What are the official names of this protein?
NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1, KappaB-Ras1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_HYDCU
Sequence: MMNQTVTEEAVRRLAEGTHHDPFQILGCHAVGKKWEVRVWLPTAESASVEGWHALTRVEGTSLFIASLTEKQKKALPLHFKVNWVEANGSEHTVVSPYTFLPQLGELDLHLYAEGRHWHVYDVLGAQVKEVDNISGVQFSVWAPAASRVSVVGDFNGWNGLRHPMRTNGQSGVWELFIPGMVSGDIYKFEIRNYQTDQLLVKTDPYAKAMEFRPQTGSIVYDSTFQWQDRDWLAARAHFDWQASPINIYEVHLGSWQRDHDGFFLNYKEIAQRLVEYVKWMGYTHIELLPISEHPLDESWGYQTTGYFSPTSRFGSPDDFRYFVNYCHENGIGVFLDWVPAHFPKDEFALARFDGTALYEHEDPRRGEHQDWGTYIFNYGRNEVRNFLIANALYWLKELHIDGLRVDAVASMLYLDYSRKDGDWLPNQYGGRENIEAIEFLKTLNAEVHAQCPGALMMAEESTSWPMVSRPTWMGGLGFSMKWNMGWMNDTLDFFQQDPIYRPYHHNQLTFSQMYAYSENFILPLSHDEVVHMKHALVSKMPGDTWQKMANMRLLMGYQTLNPGKKLLFMGGEFAQWQEWSESRGLDWYLCEQPANRGVQMLVRDLNLLYQTSPALYCHDFDQEGFEWIDCHDYEQSVLSFVRISEKESLICVFNFTPVPRYDYRIGLPETGIYEEVLNSDSELYGGGNVGNSGQLTTEDQRWMNRPCSTTLVLPPLAVVVLRKKS
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: MIAA_ALCBS
Sequence: MMPEASLPILLLMGPTCSGKTALAIEAAQTLPIEIINVDSALVYKGLNIGAARPTEEELALAPHRLLGFRDLTEPYSAADFRADALKHIEQIHNNGKLPLLVGGTVLYFKALVEGLAPLPEADPVVRAEIAALADAQGWPAVHQALAEVDPVTAARLKPTDKQRLQRALEVFRLTGRPLAAFHAEHDKTLTKSRDGLSQFSGLPYPVLSTALAPQDRAWLHEQIALRFRAMLNSGLQEEVEALRQQPQLNADLPGIRAVGYRQMWEYLDGMYGYDSMVERGIIATRQLAKRQFTWLRKWPELQWFDSNDRSQRDALFGLLAKNCKSVFS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: Y840_STRPG
Sequence: MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDSYKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN
What are the official names of this protein?
UPF0223 protein SpyM50840.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: PTH_STRP3
Sequence: MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNFKAQIGSTFINHEKVCFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKLRLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAISLTLDRVVNAVKFYLQENDFEKTMQKFNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP1B_DICDI
Sequence: MVPTTESHENNMPDNAAITQQQQDATTSSSSSVATQPPQSQIPPQPQYQYQMAPPPQTHHVHPHHVHPHHQQHPGYVPSHHHHHQQHHHHHPHHVGVPNLHHSIHQQQHPGYVPSHHHHQQQHHHHQHQHQHHQHQHHQHQHHQHHQHHQHHHTSPMGAGAGAAGMPILSMSPIGAYQPPHQLTSLYVGDLAADVNEIILNELFSKVGRNAIASIHVCRDSNTLRSLGYAYVNFFNNHDAERALDTLNYTLVHGKPCRIMWSYRDPTKRKTNVGNIFVKNLEKGVDNAMLYDTFSSFGNILSCKVEFEKGISKGYGYVHFETNDSAEKAIEKVNGTLILGKPINVERFVSKVERYKVENKVFFRNADESITIEILQQELSNRFGEIESCILKNDANGKSKGLGLVEFKNQEDAQKILTESGALIISTIDGTTTVSSNGGTIEINGKPITIDRIKSKVERFTEYRKKTTDLSLFINNIDESIDRDLIKEEFAKHGTIIGIKIVQDENARNKGFGFISFSEIQEAQKALDSLNGFTFGSKQIQVSFSNKDNNQINNKLNGNSTKITKNIIQGGASASQYTGYLPINRYQQHLPHQHINPMYTQQPYFPQQQQSSSSSQPSSSQPQPSSPSHLNGNTTTTSPNTRYSKTLNGTTPFKKSNLPQNANGTNNNNNNNNTNINKSNNTTQSNGFRNKRVPNGKPRYNNNNNSSNNNNNNNTTTNVTTTPSSTETTTPKTTITLEFITNATAEEATETLGSEVYNLVLAKYNNNIELAAKIAGMIVDAVPEHKELFEIISNGQIQSKIEEAKSLLDQPDQE
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein 1-B, PABP-1-B, Poly(A)-binding protein, cytoplasmic 1-B.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.