PharMolix/UniProtQA huggingface dataset:
Protein: GLT25_AEDAE
Sequence: MKPVSCVGLLVLLVGVLVTVKGSILFQSPKVLIVSLIRNKEHTLPYFFSYLEDQEYPKDRISLWFRSDHNEDRSIDIIKAWLKRVTKKYHSVDFGYRSDAAKRYDEKSSTHWSEDRFADVIRLKQEALDKGRKMWADFVLFLDADVLLTNPNTIAKLVSLNLPIVAPMLLSDGLYSNFWCGMTADYYYHRTDEYKEILNYEKTGEFPVPMVHSAVMVNINVQQSLNLSFDKRRLPPGHYTGPVDDIIIFAMSANYSSIPMYISNSASYGYILVPLEQGDPLEKDLEQLTNTKVYIINEHGAINLKEDLKHFVPKVPKDKMGVSHIYMINLERRPERRNKMFNNFDELGLDVEFFPAVDGRQLSDDKLRDIGVKFLPGYADPYHKRPMTMGEIGCFLSHYYIWEKMVAMNQEEVLVLEDDIRFEPYFKRRVAQVLDDARRIGGWDLIYFGRKRLQEDDEKWVVGSETLVVAGYSYWTLGYLISLQGAKKLLEEKPLEKLVPVDEYIPIMFNNHPNESWVNHFKNRNLVAWSAAPLLLYPTHYTGDDGYISDTEDSARIDNFNKVLNDTSDSSAEKKGDKEQLSSKTLMDSTISRDEHELSVANRKSEL
What are the official names of this protein?
Glycosyltransferase 25 family member.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 25 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: MUTS_LATSS
Sequence: MPQKTKETPMMAQYQKVKDQYPDAFLFYRLGDFYELFNDDAVKASQLLELTLTARNKNAADPIPMCGVPHHAAQNYIDILVDQGYKVAICEQMEDPKTAKGMVKREVVQLVTPGTVMDEKAGHAKQNNYLTAVVAQGDQFGFAYTDLSTGEMKVSQISSLDVLLNEMLSLQTKEVVVNHDVPSEVVQAFVQQQILVSYQDEGADTAEVSFVSQNISQPLALAVIKQLVVYLATTQKRHLGHLQRAQAYEPSQYLKLDHSAKMNLELTASLRTGHKSGTLLWLLDETKTAMGGRLLKQWLERPLLDLNQIKNRQNQVASFLQHYFERTNLQEALTKVYDLERLAGRVAFGSVNGRDLIQLKTSLEQIPKIKDVLTGINETQAFDQALTRLDPVDDVRTLIETAINPDSPISVTDGGIIQDGYDEQLDQYRNAMSNGKQWLAQLEAQEREATGIHNLKIGFNRVFGYYIEVTRANLSSLPEGRYERKQTLTNAERFITPELKEKEQLILEAEERSTALEYELFTQVREQVKLQIERLQTLAKGVAALDVLQSFAVVSESYHYVQPTLRTDSREIDLVDGRHPVVEKVLGRQKYIPNAVQMGKETDMLLITGPNMSGKSTYMRQLALTVIMAQMGCFVPAKSANLPVFDQIFTRIGAADDLISGQSTFMVEMMEANRAIMSATANSLILFDEIGRGTATYDGMALAQAIIEYIHDHVHAKTLFSTHYHELTALADTLTALRNVHVGAVEENGELVFLHKMLAGPADKSYGIHVAKLAGMPETLLQRADVILGQLEDKPKAPVQPATVAPAQPAAAAVEEQMALFEPEVAAPVDKKTDKVVAAIKNFDLMSATPLEALNQLYEWQKQLNKH
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RTN2_HUMAN
Sequence: MGQVLPVFAHCKEAPSTASSTPDSTEGGNDDSDFRELHTAREFSEEDEEETTSQDWGTPRELTFSYIAFDGVVGSGGRRDSTARRPRPQGRSVSEPRDQHPQPSLGDSLESIPSLSQSPEPGRRGDPDTAPPSERPLEDLRLRLDHLGWVARGTGSGEDSSTSSSTPLEDEEPQEPNRLETGEAGEELDLRLRLAQPSSPEVLTPQLSPGSGTPQAGTPSPSRSRDSNSGPEEPLLEEEEKQWGPLEREPVRGQCLDSTDQLEFTVEPRLLGTAMEWLKTSLLLAVYKTVPILELSPPLWTAIGWVQRGPTPPTPVLRVLLKWAKSPRSSGVPSLSLGADMGSKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKIPGTGALASAAAAVSGSKAKAE
What is the function of this protein?
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity (PubMed:15286784).  Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity).  Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell (By similarity).
What are the official names of this protein?
Reticulon-2, Neuroendocrine-specific protein-like 1, NSP-like protein 1, Neuroendocrine-specific protein-like I, NSP-like protein I, NSPLI.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane, sarcolemma, T-tubule; Multi-pass membrane protein. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, cytoskeleton. Note=Localizes to intermediate filaments in mononucleated myoblasts and to Z lines in mature myotubes.
Protein: NU1M_DROGU
Sequence: MEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLNSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALIGFKILLFSLL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EFTS_BARBK
Sequence: MSITAAQVKELRELSGAGMMDCKAALMETNGDIETAVDWLRKKGMAKADKKAGRTAAEGLIGIASKGLSAVVVEVNSETDFVARNDAFQTIVRNVATAALDTEGSVESVSASIYPGSEKTVEEAIKDAIGTIGENMAFRRSAKLSVQNGAVATYIHNSVADGLGKLGVLVGIETTGDKEVAVDFARKVAMHIAATNPLALTVADVDASIVEREKAIFSDQARQSGKPENIIEKMVEGRIRKFYEEVVLLSQAFVMNPDVTVEASLKDAEKMIGAPAKITGFVRFALGEGVEKEEVDFAAEVAAAAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P4HA3_BOVIN
Sequence: MGPAARLAALLAVLAFRAGDPAEVAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYHKVLSLHEDSATPVSNPLLAFTLIKRLQSDWKNVVHSLEASENIRALKDGYERVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAVTDLYSPRRLFSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFQAGNVLCALNLSREFLLYSPDNKRVARNVLKYEKLLAESPNQAVAETVMQRPNVPHLQTRDTYEGLCQTLGSQPTHYRIPSLYCSYETSSSPYLLLQPVRKEVIHLEPYVVLYHDFVSDAEAQTIRGLAEPWLQRSVVASGEKQLPVEYRISKSAWLKDTVDPVLVTLDHRIAALTGLDVQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMNSGNRVATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDGDTLHAACPVLVGDKWVANKWIHEYGQEFRRPCSSRPED
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
What are the official names of this protein?
Prolyl 4-hydroxylase subunit alpha-3, 4-PH alpha-3, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RS20_STAA2
Sequence: MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PHS_ACICJ
Sequence: MIPRLTDAERAALVDLLPEWSLAKDRDAIERRFAFADFSEAFAFMTRVALLAEKHDHHPEWSNVYNRVTILLSTHDAGGLSARDIRLAEAIDGLA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: COBQ_DESHY
Sequence: MSGKKAAARLMIQGTSSNVGKSVLAAAFCRIFYQEGYHVAPFKAQNMALNSFITRSGGEMGRAQVVQAQAAGLEPDVRMNPVLLKPTGHTGSQVIVLGKAQGTLSALKYHGDYQRKTWPIVEEALHELLEEHEIVVIEGAGSPAEVNLKQNDIVNMRVAKEAQAPVLLVADIDRGGALASVVGTLELLEPEERQLVQGIVMNKFRGDIKLLQPALDFLEERTGIPVVGVVPFYDQFKIPEEDSVVLEEQNTSKRDQGKSRDEALDVAVIRLPYLSNFTDFDPFEDEPDVILRYVREPSELGEPDCVIIPGSKNTLSDLRFLWESGLGEKIIKFWQEDVPIIGICGGYQMLGRIVRDPLGTESDLKEIAGLGILPMETEFELDKHTVQSRGKVVGGELFLARCQGTEITGYEIHMGRSQGEGHSLFEIEAQETAYGDGMSAGSAVGTYLHGIFDNDPLRTALLEWLWERRGGTRPVGETMSQAAIREQSFNELADWVRNSMDMEKIRAMMGLHKG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: CYSE_ECOLI
Sequence: MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSALSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPLLYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHATGIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI
What are the official names of this protein?
Serine acetyltransferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA1_LACBS
Sequence: MSVTVVLGSQWGDEGKGKLVDILAADIDVCARCAGGNNAGHTIIVPIDGVLKTFAFHLLPSGLVNPRCTGLIGSGLVVHVPSFFAELDALEAQGLDCSNRLFISDRAHLVFDFHQIVDGLKEVELGGKSIGTTKRGIGPAYSGKASRSGLRVHHLFDHETFAEKFRKLVEGRYKRYGHFEYDTEGEIERYKKLAERLRPYVVDSVAYIHKAITSGKKVLVEGANALMLDLDFGTYPYVTSSSTTIGGVCTGLGIPPKMIGRTIGVVKAYTTRVGGGPFPAEQLNDIGVHLQEVGREYGTTTGRRRRCGWLDLVVLRHSSMINGYDSLNLTKLDVLDQLPEIKVATRYLVDGKELEGFPADLELLANVDVEYVTLPGWQSSIENITTYDDLPENCKGYIKFIEDSLNVPIEWIGVGPARKSMVRKELKQ
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase 1, AMPSase 1, AdSS 1, IMP--aspartate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABI_STAAR
Sequence: MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI, ENR, NADPH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: GLYA1_BURPS
Sequence: MFDRAQSTIANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRVKALFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNEAEDIDYEAAEQLAHEHKPKLIVAGASAFALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKQINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAQTLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNAHITVNKNAIPNDPEKPFVTSGVRLGSPAMTTRGFGPQEAELVGNLIADVLEHPEDAATIERVRAQVAELTKRFPVYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 1, SHMT 1, Serine methylase 1.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C2_OENPA
Sequence: MIWHVQNENLILDSTRIFMKAFHLPLFDGSFIFPEGILIFGLILLLMIDSTSDQTDIPWFYFISSISLVMSITALLFRWREEPRILFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHPLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDANGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLFTSVVSIYYYLKIIKLLMTGRKQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PLSX_MYCGA
Sequence: MFRIAVDCMGFENSVSEAVKAVIKYAKKHKDLSFVLVGDENQIRPLVENKKYLNYRIVHTTNEIGMSDSVLTAYRKKDSSMYLTIELLKNNEVDTIISAGSSSAYVALTYNLIGKIHHKIKVGFMSYVPTVTKRGFWFLDVGANKEYLGEELYYLGKMANTFITSVFNYQPRLGVLNIGAEKNKGFEYHQVVYNLLENDKTVDFLGFIEPRGLIKGECDLLVSDGYSGNLVLKSLEGALKSVGKILKKNYKINPLGALFSANVIYQITKTFDYKNNAGAVVLGLNKLVLKTHGSADAKQFYSTIRLAHESLLNNLIEKITKECSTFLN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: NUOA_ACIAC
Sequence: MNLDQYLPVLLFILVGIGVGVVPLVLGYVLGPNRPDAAKNSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLFPWAVALHEVGMTGFVAVIVFLAILVVGFAYEWKKGALDWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR7_MARPO
Sequence: MSRKSIAEKQVAKPDPIYRNRLVNMLVNRILKNGKKSLAYRILYKAMKNIKQKTKKNPLFVLRQAVRKVTPNVTVKARRIDGSTYQVPLEIKSTQGKALAIRWLLGASRKRSGQNMAFKLSYELIDAARDNGIAIRKKEETHKMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NRFC_HAEIN
Sequence: MTVCSRRNFVSGMGAVILMTGTSLPAFAKENKADKPKRYAMIHDENACIGCTACMDSCRDVNQVPEGVSRLEILRSEPYGEFPNQEYEFFRQSCQHCTNAPCVAVCPTGASFIDKETGIVDVHKDLCIGCQYCIAVCPYRVRFIHPIHRTADKCNFCRDTNLANGKQPACVEACPTKALTFGDMNDPTSAVSRKVKEKPVYRTKVELGTQPNLYHIPFQHGEPRR
What is the function of this protein?
Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes.
What are the official names of this protein?
Protein NrfC homolog.
Protein: Y615_ALIFM
Sequence: MQIWVDADACPKVVKEVLFRAATRTGIKLTLVANHYIPVPSAANIRSMQVEAGFDVADDEIVKRSEAGDLVISADIPLAAELIEKKVQVLNPRGELYTEATIKARLNIRDFMDTMRASGIQTGGPAPLSQTERREFANQLDRILAKAKI
What are the official names of this protein?
UPF0178 protein VFMJ11_0615.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: Y1609_DICDI
Sequence: MVNDRLYICYCDNGYILIDNTINPYCLLINGSTSPNTTTTIIINNTSNNNNNNNNNHMNWTIPIVIIVSIFILLIIGSISLYLYKKYCSKPKRVHYQLIR
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0291932.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: THI5_LEGPH
Sequence: MAMSSLKSRVTLLLNWYTNPYHTPILVAQQLGFYSEEDIKLAILEPADPSDVTEIVGLGTVDFGVKAMIHTVAAKAKGYPVTSIGTLLDEPPTGLIALKSSGINSFQDIVGKRVGYIGEFGKKIIDDLASLAGIDPTSYKTVRIGMNVTDAIYRDVIDTGIGFINFQKVELEHLCGETVFLRIDQLAGLGCCCFCSIQFIVPEITLQQPELVKGFLRATQRGAAYTTEKPEEAYELLCQAKPQLRTPLYQKIFTRTLPFFSRTLINVDRDWDKVGRYTKHLKIIDEHFDISQCYTNRFLPDTPYSDLKPIACCLEN
What is the function of this protein?
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway (PubMed:33034117).  Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP) (Probable).  The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme (By similarity).  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme (By similarity).
What are the official names of this protein?
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase, HMP-P synthase, Hydroxymethylpyrimidine phosphate synthase, Thiamine biosynthesis protein 5, Thiamine pyrimidine synthase.
What is the protein family that this protein belongs to?
Belongs to the NMT1/THI5 family.
Protein: NDHJ_FAGEA
Sequence: MQGRLSAWLVKHGLVHRSLGFDYQGIETLQIKPEDWHSIAVILYVYGYNYLRSQCAYDVEPGGLLASVYHLTRIESGVDQPEEVCIKVFVPRRNPRIPSVFWVWKSVDFQERESYDMLGIFYENHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: LEUD_PASMU
Sequence: MPKEFKQHTGIAVPLDASNVDTDAIIPKQFLQKVTRIGFGQHLFHEWRFLDDEGKQPNPDFVLNYPRYQGASILLARENFGCGSSREHAPWALDDYGIRVIIAPSFADIFYGNSLNNQMLPIRLSDEEVEELFQFVNANEGATITVDLETQRVSANNKVYSFEIDPFRRHCLLNGLDNIGLTLQHEAKIAEYESNIPAFLR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: TCTP_CUCMA
Sequence: MLVYQDLLTGDELLSDSFPYKELENGMIWEVEGKWVVQGAVDVDIGANPSAEGDGEDEGVDDQAVKVVDIVDTFRLQEQPTMDKKQFIAYIKKFIKLLTPKLEGEKQEAFKKNIEGATKFLLPKLKDFRFFVGESMHDDSCIVFAYYREGATDPTFLYLAPALKEVKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP, CmTCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AR6P4_XENLA
Sequence: MMDGTHAIKRSRSRSPKVSQSKSSKKKKRSSSRCRSGSDSPARKHSTLAKYRAEVPDRRKKERRKKRRKRTVSTTSSSSSESSSSSSSSSSDDSGDSTCKSKRSSHRKKKNKKQIKRKKAKKNKKLKKKTSFKLECQDTKSTEKEVLPGPSVNPCKKESPEVSGPALTDEQKSRIQAMKPMTKEEWDAQQSVIRKVVDPETGRIRLIKGDGEVLEEIVSKDRHKEINKHATQKDGLEFQMHSGMF
What is the function of this protein?
May be involved in modulating alternative pre-mRNA splicing.
What are the official names of this protein?
ADP-ribosylation factor-like protein 6-interacting protein 4, ARL-6-interacting protein 4, Aip-4.
What is the protein family that this protein belongs to?
Belongs to the ARL6IP4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus speckle.
Protein: IOLC_CLOBA
Sequence: MGYIKFQKDRKFEIVPIGRVAIDFNPTDINRPLSKSMTFKKYLGGSPANIAVGLSRLGKKVGFIGKVSKDQFGKFVVDYFNNEGIDTSQIKYAENGESLGLTFTEIASPTESSILMYRNGIADLELDVNEIDEEYIKNTKAIVISGTALAKSPSREAALKALELAKKNDTVVIFDVDYREYNWKNKDEIAIYYSIVGKQSDIVMGSREEFDLMESLIVKEKSTDEESAKRWLGFGNKIVVIKHGKEGSTAYTNDGKSYKIKPFPVKLLKSFGGGDAYASAFIYGILEEWDIMDALEFGSASAAMLVASHSCSEDMPTVKEINEFIKEKKEQYGEMIARG
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: RSMA_METAC
Sequence: MVRSILNKYNIKGGTFDQHFLIDIGYLDRIVVAAELSPQDTILEIGAGIGNLTERLARRAKKVIAVELDPALVSVLHDRFDKVENIEVIAGDALKVDFPEFDKVVSNLPYSISSEITFKLLRYKFKLGILMYQYEFAARMVSPPGRKDYSRLTVDTYYFADASILMKVPKGAFQPAPEVDSAVVKLVPRPSPFEVRDEAFFLEFVAAVFSQRRKKLRNSILNTNSMLKIPDIKEVVNQLPDDFVNKRAENLTPEELASVANMLFDLKSR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTG_STRR6
Sequence: MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANEPSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSSPAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIRDTSRRSRREGAKPAKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAFLAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEMLAAMDKNLSLYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN
What is the function of this protein?
Mutations in this gene suppress deletion of PBP2b (penA); truncation at residue 168, undefined changes between residue Ile-447 and Ala-505, and mutation of Ala-505 suppress the penA deletion.  Probably part of the elongasome which synthesizes peripheral peptidogylcan.
What are the official names of this protein?
Endolytic murein transglycosylase, Peptidoglycan polymerization terminase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase MltG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Localizes to midcell in the presence and absence of khpB (also called eloR/jag).