PharMolix/UniProtQA huggingface dataset:
Protein: DYR1_HALMA
Sequence: MTMIPDTELVLVVAADENNVIGLDGGVPWHYPEDVRQYKNRIAGHPIILGRRTFESMKPIPDCYTVVLTSDDRRSADSETVEYATTPQIAVEAAARAGASGAFAGDSAGADSSPPVTYVIGGEAVYDLFLPFAGRVFLSRIHEHNEGDRYFPDLGAEWTELSREPHDGFDVIEYEQASPRPLDDL
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase 1.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: STO1_CAEEL
Sequence: MQPSETVEMQEMAQPSGQQRDVEARVQSAPANHSHDAGCTEMFCIAMSYVLIFLTFPVSVFMCIKIVQEYQRAVVFRLGRLVPDVKGPGIFFIIPCIDTFLNIDLRVASYNVPSQEILSRDSVTVSVDAVVYFKVFDPITSVVGVGNATDSTKLLAQTTLRTILGTHTLSEILSDREKISADMKISLDEATEPWGIKVERVELRDVRLPSQMQRAMAAEAEATRDAGAKIIAAEGELRASAALAEAATIISKSEGAMQLRYLHTLNAISSEKTSTIIFPFPMEILGGISKVGSGGTSQNFPVQEMMNAALQSIQRQDTVPATASSSGSRL
What are the official names of this protein?
Stomatin-1.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATRF1_STAAR
Sequence: MRKFLSKEYHRTNPLWHVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQILNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
What are the official names of this protein?
Putative acetyltransferase SAR0816.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: ABEC1_PONPY
Sequence: MTSEKGPSTGDPTLRRRIESWEFDVFYDPRELRKETCLLYEIKWGMSRKIWRSSGKNTTNHVEVNFIKKFTSERRFHSSISCSITWFLSWSPCWECSQAIREFLSQHPGVTLVIYVARLFWHMDQRNRQGLRDLVNSGVTIQIMRASEYYHCWRNFVNYPPGDEAHWPQYPPLWMMLYALELHCIILSLPPCLKISRRWQNHLAFFRLHLQNCHYQTIPPHILLATGLIHPSVTWR
What is the function of this protein?
Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs.  Form complexes with cofactors that confer differential editing activity and selectivity.  Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA.  Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA (By similarity).  May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (By similarity).
What are the official names of this protein?
C->U-editing enzyme APOBEC-1, Apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1, APOBEC-1, Apolipoprotein B mRNA-editing enzyme 1, mRNA(cytosine(6666)) deaminase 1.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBT2_ARATH
Sequence: MVVEEQSLENGGSVHVVKGESNFRNVVCGPVRWLKMLSSELHWSFVFGVVSLYGINQGLGGSLGRVATEYYMKDVQKVQPSESQALTAITKIPWIIKPLWGILTDVLPIFGFHRRPYFILAGVLGVVSLLFISLHSNLHLYLALFWMTISSAAMAIADVTIDACTAYNSIKHPSLASDMQSLCSLSSSIGALLGFFMSGILVHLVGSKGVFGLLTFPFALVSVVGIVFSEPHVPGFSYKQVNQKFTDAGKAMWRTMKCSDVWRPSLYMYISLTLGLNIHEGLFYWFTDSKDGPLFAQETVGFILSIGSIGSILAATLYQLVLKDHPFRGLCLWTQLLFALSGMLDLILVFRLNLKFGLPDYLFIVVDEIVSQMIGRLKWMPLLVLTSKLCPHGIEGTFFALLMSIDNAGLMTSSWLGGIMLHVLKVTRTEFGNLWLAVLVRNVMRLLPLCFLFLVPKGDQNTFKLPDEIMGEDSDEEKDEKEGTRNLELASLVHSVDRR
What is the function of this protein?
Could mediate folate transport.
What are the official names of this protein?
Probable folate-biopterin transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECR_MAGSA
Sequence: MVGPEIERLIQLLSRLPGLGPRSARRAALRLVEKRESLLVPLAQAMADAAARVRTCSVCGNFDTIDPCAICADHRRDPSMLCVVEDVAGLWAMERTGSFKGRYAVLGGLLSALDGVGPEDLGIESLVARALDPAITEIILATPATVEGQTTAHYVAERLAPCNVTVSGLAHGVPVGGELDHLDDGTITAALRARRVF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RS12_EDWI9
Sequence: MATINQLVRKPRAKKVEKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQSRSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS11_MAGSA
Sequence: MAKPAAAARPRRRERKNITSGVAHVNATFNNTMITITDAQGNTISWSSAGMQGFKGSRKSTPYAAQVAAEDAGRKASEHGMRTLEVEVKGPGAGRESALRALQAVGFQITSIRDVTPIPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: ASPG1_ECO57
Sequence: MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRPEMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALSFMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNRTTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIYPGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSGKVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQELDTETIRKAMSQNLRGELTPDD
What are the official names of this protein?
L-asparaginase 1, L-asparaginase I, L-ASNase I, L-asparagine amidohydrolase I.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAA_CROS8
Sequence: MKYDTSELCDIYQEEVNVVEPLFSNFGGRSSFGGQIITVKCFEDNGLLYELLEENGRGRVLLVDGGGSVRRALIDAELARLAVQNEWEGLVVYGAVRQVDDLAELDVGIQALAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_LEGPH
Sequence: MRKVKPKLNLTSQTARIVNLSHDGRGIARVNGKATFIQGALPGEMVEFQYTRVKKDFDEGKLLSIIEPSTLRVEPKCPHYQMCGGCSLQHMSAEEQIRFKQSHLLDLLSRYGHTEPQSMLSPLTSHHWNYRNKARLSTRFVEKKQSTMVGFRERNNPRFITEINQCPILNSKIDTDIVHLRKLIDTMEDKQCIAQIEVAAGDNEVALIFRNLTPLTEQDELKIRKFAEQFQYKVFLQPGGLDSVFCFYPSDAHAYLSYELPDYQITFQFHPNDFTQVNAELNRKMVTQAIQLMELKNSDIVLDLFCGLGNFSLPMAKHCSRVIGVEGNKNMVERAYMNAKSNHITNVDFYAANLDDVMEVRNLVNTSFSKVLIDPPRSGALEIVKQIDSIDPERIVYVSCNPITLARDTDILVNQKGYVLITAGVMDMFPHTAHVESIALFQKG
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: TGT_STRP2
Sequence: MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSIGGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIRLTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TRXB_STAAC
Sequence: MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGALC_PENRW
Sequence: MRLFALLPVLLGLISSHFVSATDNGKTTDVTWDKYSLSVKGERVYVFSGEFHYQRLPVPELWLDVFQKLRANGFNAISIYFFWSFHSASEDTFDFENGAHDVQRVFDYAKQAGLYVIARAGPYCNAETSAGGFALWASNGQMGSTRTSASSYYDRWYPWIQEIGKIIAANQITNGGPVILNQHENELQETIHSADNTVVKYMEQIKAAFSDAGIIVPSTHNEKGMRSMSWSTDYQDVGGAVNIYGLDSYPGGLSCTNPNSGFNLVRTYYQWFQNYSSSQPEYLPEFEGGWFSAWGGSFYDQCSTELSPEFADVYYKNNIGSRVTLHNIYMVMGATSWGQSAAPVVYTSYDYSAPMRETREIRDKLKQTKLIGLFTRVSSGLLQTQMEGNGTGYTSDASIYTWALRNPETHAGFYVLAHSTSSSRAVTTTSLNVNTSAGALTIPNIELAGRQSKIIVTDYQTGDGSSLLYSSAEVLTYATLDVDVIVFYLNIGQKGEFAFKDAPTHLTFKTYGNSKVSSAKSDHGTKYTYCQGDGTTVLKFSHGVLVYLLDKETAWNFFAVPTTSNPRVAPSEQILALGPYLVRTASVSGHTVSLVGDNANATSLEVYTGNSKVTQIKWNGKETPTKKTAYGSLIGSAPGAEHAKLSLPTLKSWKAQDTLPEINPDYDDSRWTVCNKTTSVNSVAPLTLPVLYSGDYGYHAGTKIYRGRFDGVTATGANITVQNGVAAGWAAWLNGVYVGGAIGDPDLAATSAELEFTSSTLRRKDNVLTVVMDYTGHDQANVKPNGSQNPRGILGATLLGGDFTSWRIQGNAGGEANIDPVRGPMNEGGLYGERLGWHLPGYKGSKTATSESPLDGVSGAAGRFYTTTFKLDLDSDLDVPIGLQLGASADAPAVVQIFMNGYQFGHYLPHIGPQTRFPFPPGVINNRGENTLAISLWALTEQGARLSQVDLVAYGAYRTGFNFNHDWSYLQPQWENNRGQYV
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
What are the official names of this protein?
Probable beta-galactosidase C, Lactase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS9_CHLPD
Sequence: MKEVIDTVGRRKTSVARVFMSPGKGRVIINKLPAEEYFRDEVKRQQALRPLALTEKMEDFDIKVNVHGGGVSGQTGAVSLAIARALTEFDESARAVLKKEKLLTRDPRMVERKKFGRKKARKRFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: GATA_USTMA
Sequence: MRNRGVHRCIISVGSSNAAHVRRCAVSCCTLASANLARRDLTSSSAAHSNSGTFRDGRFDPYNAIIADITSSSTSSPSGAATKGRLKGWTAAIKSNICIRDHPTTCSSAMLQHFKPTFDASAVSLLRQAGTDIRYITNCDEFGMGSNNIHSVHGPVRNPASPRSESGPIWNLEEERVAGGSSGGSAAVVKAGLVRFALGSDTGGSVRLPAAYCGIVGLKPSYGLVSRWGLVSYADSLDTVGVLAKTVEDVSVVHSVLSQNDPHDPTSASQQARAAAATTVETLISALPSSNSSQPLKGLRVGVPKEYFPVELHPRVLPPFRRAVAGLEELGAQVVQITLPSTPSALSAYYIISSAEASSNLARYDGVEYGFHTPSAPGHHAYAATRTTAFGDEVRKRILLGTFALTADAYDNYFLQASRVRAQVQEDFASALRIRNASTKDDKLTARDQEGVDVILHPSAVDTAPTLAAAMQPGEPSAAEYVQDVLTVPASLAGLPALAVPAGAASDDGWPVGVTLVSQWGCDEVLLHVGKHLQTQLGT
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPF_CALFG
Sequence: MKNVTDSFVSLGHWPFAGSFGFNTDILATNLINLSVVLGVLIFFGKGVLSDLLDNRKQRIWSTIRNSDELREVAIEQLEKARARLRKVEREADEFRVNGYSEIEREKWNLINATYENLERLENYKNETIHFEQQRAINQVRQRVFQQALQGALGTLNSRSNSELHLRTISANIGMLGAMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL10_BURP1
Sequence: MPLNREDKQAVVAEVAAQVAKAQTVVLAEYRGIAVGDLTTLRAKAREQKVYLRVLKNTLARRAVEGTPFAPLAEQMTGPLIYGISEDAIAAAKVVHDFSKSNDKLVIKAGSYDGKVMDKAGVQALASIPSREELLSKLLFVMQAPVSGFARALAALAEKKQAEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RS20_CUTAK
Sequence: MPNIKSQIKRVKTNEKSRQRNKAVKSALRTYVRNFRRAAEAGDVEAATKAARVANRQLDKAASKGVIHKNQAANRKSAISKKLNSLAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: IMP2L_MOUSE
Sequence: MAQSQSWARRCFKAFCKGFFVAVPVAVTFLDRVACVARVEGSSMQPSLNPGGSQSSDVVLLNHWKVRNFEVQRGDIVSLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRLVKVPRGHMWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQRLESVLPPERCPLQTGEK
What is the function of this protein?
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space.  Known to process the nuclear encoded protein DIABLO (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease subunit 2, IMP2-like protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family. IMP2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ATPE_BACC1
Sequence: MKTFPVSIVTPDGPVYEKEVEMVSVKAESGEMGILPGHIPTVAPLKISAVRLKNGGHTDYVAVSGGFIEVRPDKVTVLSSSAEEANHIDIHRANEAKRRAEQRLQDKQAHVDFKRAEMALQRAVNRLNVSDMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL32_ACTP7
Sequence: MAVQQNKKSRSRRDMRRSHDALTTAAVSVDKTTGETHLRHHVTADGYYCGRKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ATPB_STRGC
Sequence: MSSGKITQVIGPVVDVAFAAGDRLPEINNALVVYKNDEKKSKIVLEVALELGDGVVRTIAMESTDGLTRGLEVLDTGRPISVPVGKETLGRVFNVLGDTIDLDAPFGDDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQLGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDEEKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILEGKHDKLPEDAFRGVGSIEDVLAKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TYSY_NOCSJ
Sequence: MRAYLDLLQRVVDEGVPKGDRTGTGTLSVFGHQMRFDLRAGFPLVTTKKVHTRSVFGELLWFLRGDTNVKWLQDRGITIWDEWADEQGDLGPVYGYQWRSWPTPDGRHVDQIAQVVEQIRDSPDSRRHVVSAWNVADIPDMALAPCHTMFQFYVAPPGPGEESGPGRLSCQLYQRSADVFLGVPFNIASYALLTHMVAQVTGLEVGDFVHTLGDAHLYSNHLDQARLQLTREPRPLPRLVLDSSVTELDAFDLEHIAVEGYDPHPGIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_ECODH
Sequence: MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CH60_TROW8
Sequence: MAKKITFNEDARRGLERGLNTLADTVKVTLGPRGRNVVLEKKWGAPVITNDGVTIAKEIELDDPYEKIGAELVKEVAKKTDDVAGDGTTTSVVLAQAMVREGLKNVAAGADPISLRRGIEKSVAAVSKALLTSAKEVETEAEIAACASISAGDPQIGDIIAQALEKVGKEGVVTVEESNTFGTELEITEGMRFDKGYLSAYFVTDAERQETVFENPYILICDSKISSVKDLLPVVDKVIQSGKQLLIIAEDVDGEALATLVVNKIRGIFKSVAVKAPGFGDRRKMMLQDIAVLTGGQVISEEVGLKLENATLDLLGCARKVVVSKDETTIVDGAGSSDQIAGRVSQIRKELENSDSDYDREKLQERLAKLSGGVAVIRSGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGAALLQSGTSALKDLQLTSEEAVGRNIVRSAIEAPLRQISLNAGLEPGVVVGKVSSLPQGHGLDASTGEYVDMLSRGISDPVKVTRSALENAASIAGLFLTTEAVVAEKPEPKPAPGPADPGAGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_RUEST
Sequence: MRIGLYPGTFDPITLGHIDIIRRATLLVDRLVIGVAINRDKGPLFDLEERVAMIEAECAKLTEQTGTEIVVHPFENLLIDCARDVGAQVIVRGLRAVADFEYEFQMVGMNRALDDSIETVFLMAEARHQAIASKLVKEISRLGGDVSKFVTPLVRERLAERLGQR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA2_EXISA
Sequence: MTYNQTRSQEAFEQARPLMPGGVNSPVRAYKSVGMTPIFAERGEGSRVYDIDGNEYIDYVLSWGPLILGHRDPVVTKAIQEQAEKGWTFGTPTELETKMAELVIDRVPSIEMVRMVNSGTEATMAALRLARGYTGKTKILKFEGCYHGHGDSLLIKAGSGVATLGLPDSPGVPKELASHTLTVPYNDLDAVRVAFEKYGDDLAGVIVEPAAGNMGFVPPQPGFLEGLREITEQNGALLIFDEVMTGFRVGYNCAQGYFGVTPDLTCLGKVIGGGLPVGAYGGKREIMEQIAPQGPIYQAGTLSGNPLAMIAGYTTLSQLKPEHYEEFERKADRLAEGFTQAGEKYNIPHDTNRAGSMFGFFFTNEKVTNFEKAKSANLEMFRSYYQKMAARGVFLPPSQFEGLFLSTAHTDEDIEKTIAAVEATFKELQEEFSL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_SINFN
Sequence: MNDAATVLGTADLQEILRLLPHRYPFLLVDRIIEIDDDNSAIGIKNVTANEPHFTGHFPEKPIMPGVLLIEGMAQTAGAICARKTGIGSNLVYFMTIDNARFRKPVVPGDRVEFHVTKQKQRGNIWKFHCDAKVDGQLVAEADIGAMIVSKEDA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2B_BOTJR
Sequence: DLWSWGQMIQETGLLPSYTTY
What is the function of this protein?
Snake venom phospholipase A2 has a high enzymatic activity and produces moderate myonecrosis in skeletal muscle, but shows no neuromuscular activity in mouse phrenic nerve-diaphragm preparations.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 BjIV, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SSTT_CITK8
Sequence: MTTQRSSGLLQRLVQGSLVKQILIGLILGILLALVSKPAAEATGLLGTLFVGALKAVAPVLVLTLVMASIANHQHGQKTNIRPILWMYLLGTFSAALTAVVVSFLFPSTLQLTTGATDITPPSGIVQVIHGLLMSIVANPIHALINANYIGILVWAIGLGFALRHSNQTTKNLVNDLSDAVTFIVKLVIRFAPIGIFGLVASTLATTGFSALWGYAQLLLVLIGCMAIVALVINPLLVFLQIRRNPYPLVLTCLRESGVTAFFTRSSAANIPVNMSLCEKLNLDRDTYSVSIPLGATVNMAGAAITITVLTLAAVYTLGIPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNEIAMQVVAVGFIIGVLQDSCETAINSSTDVMFTAAVCQAEDARLAKSALRS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_MYCBO
Sequence: MCHGGTWAGDYVLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSAISVADVVASLTRDVADFPVPGVEFKDLTPLFADRRGLAAVTEALADRASGADLVAGVDARGFLVAAAVATRLEVGVLAVRKGGKLPRPVLSEEYYREYGAATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAVVVELAGLSGRAALAPLPVHSLSRL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.