PharMolix/UniProtQA huggingface dataset:
Protein: FTRC2_SPIOL
Sequence: MKALQASTSYSFFSKSSSATLQRRTHRPQCVILSKVEPSDKSVEIMRKFSEQYARKSGTYFCVDKGVTSVVIKGLAEHKDSLGAPLCPCRYYDDKAAEATQGFWNCPCVPMRERKECHCMLFLTPENDFAGKDQTIGLDEIREVTANM
What is the function of this protein?
Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
What are the official names of this protein?
Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic, FTR-C, B1, Ferredoxin-thioredoxin reductase subunit B, FTR-B.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin thioredoxin reductase beta subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FAD3C_SESIN
Sequence: MASWVLSECGLRPLPRVYPKPRTGHPLLNSNPTKLRFSRTDLGNGSSFCLSSGILREKNWALRVSAPLRVLQVEEEEENKEGERVINGGEEFDPGAPPPFKLSDIREAIPKHCWVKDPWRSMGYVVRDVAVVFGLAAVAAYFNNWVVWPLYWFAQSTMFWALFVLGHDCGHGSFSNDPKLNSVVGHILHSSILVPYHGWRISHRTHHQNHGHVENDESWHPLSEKIYKNLDTATKKLRFTLPFPLLAYPIYLWSRSPGKQGSHFHPDSDLFVPNEKKDVITSTVCWTAMLALLVGLSFVIGPVQLLKLYGIPYLGNVMWLDLVTYLHHHGHEDKLPWYRGKEWSYLRGGLTTLDRDYGWINNIHHDIGTHVIHHLFPQIPHYHLIEATEAAKPVLGKYYREPKKSAPLPFHLLGDLTRSLKRDHYVSDVGDVVYYQTDPQLTGAEKS
What is the function of this protein?
Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes.  It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol.
What are the official names of this protein?
Omega-3 fatty acid desaturase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein.
Protein: AN_ELHVK
Sequence: MDFLSILPPQRHCTSELCDNDESVQAIISALEYTGLAKILTETFSADEFVEALDARLLYIAHIILSCKETNVPINTDTFLCPLAERIKVDVDDLNAGSLKCMKVLLHHCTNRYFIKIVEKMTRGQSSNLLWFLVRNELVTGSSVVKQCSYKPGLNSVAHGIFRPASRFEVFGKVHEPIVRDVIATFVERRPIPVSETLGLLIDPFSGTFGASIDLCYGIEEHDDGFVTVGERAHVYEIKCMARYIYSAADVEGFLDNPTLKGFASLIKGATFPLIEHRLPGATPSSGAHIVSHDRMFETNRKRKSIYESNDYVRRLLNINRGVKSTVYIFREKPQPDERDKLTLECLAKFTANIFLNARHKYFDQTSMQYFVVTQHYINDHPDPECIEPDTLPRVSVVTALFKTRNIGTHHSLEVNHKTYPNSAIPFALIVTPVAFDAEILSVFLRETFDNYAQQVYNKSKIRLWDPNFLRGFVASHRELEKTP
What is the function of this protein?
Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules.  Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate.  Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides.  Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.
What are the official names of this protein?
Alkaline nuclease.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae alkaline nuclease family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: APRD_PSEAE
Sequence: MARLGSSVTNEIKQALAASRGALRSVAAFSGVINLLMLVPSLYMLQVYDRVLSSANEVTLLMLTLMALGVFVFMGALEALRSFVLVRVSERFDGQLHGRIYAAAFERNLRAGGQEASQALHDLTTLRQFITGQALFAFFDAPWFPVYLLVIFLFDPWLGLLSLVGALALMALAWFNERATRAPLAKAGELSIKSGQLASNNLRNAEVIEAMGMLGSMRGRWERLHQAFLDQQSLASERAARINALSKYLRIALQSLVLGLGAWLAVEGRITPGMMIAGSILMGRALGPIDQLIGVWKQWGAARDAYRRLSGLLDEFPARERRMELPEPRGHLLLESLDAAPPGSEARTLRGLTLAIPAGSVVGVIGPSGSGKSSLARVVLGIWPTLHGSVRLDGAEIRQYERETLGPRIGYLPQDIELFAGTVAENIARFGEVQADKVVEAARLAGVHELVLRLPQGYDTVLGVGGAGLSGGQRQRIALARALYGAPTLVVLDEPNSNLDDSGEQALLAAIQALKARGCTVLLITHRAGVLGCADRLLALNAGQLHLYGERDQVLAALNNQRAASASQQRADYRVAGYGAPQVVAAPRQGGVE
What is the function of this protein?
Involved in the secretion of alkaline protease.
What are the official names of this protein?
Alkaline protease secretion ATP-binding protein AprD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Alkaline protease exporter (TC 3.A.1.110.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RU1C_MONDO
Sequence: MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVRDYYQKWMEEQAQSLIDKTTTAFQQGRIPPNLFSAPPLGGPMIPPPHPSMMGPPPPGMMPVGPPPGMRMPMGGHMPMMPGPPMMRPLPHPMMVPTRPVMPRPDR
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EF1A_PYRAB
Sequence: MPKEKPHVNIVFIGHVDHGKSTTIGRLLYDTGNIPETIIKKFEEMGEKGKSFKFAWVMDRLKEERERGITIDVAHTKFETPHRYITIIDAPGHRDFVKNMITGASQADAAVLVVAATDGVMPQTKEHAFLARTLGIKHIIVTINKMDMVNYDQKVFEKVKAQVEKLLRTLGYKDFPVIPTSAWNGDNIVKKSDKMPWYNGPTLIEALDQIPEPEKPVDKPLRIPIQDVYSIKGVGTVPVGRVETGKLKVGDVVIFEPASTIFHKPIQGEVKSIEMHHEPLQEALPGDNIGFNVRGVSKNDIKRGDVAGHPDKPPTVVRTKDTFKAQIIVLNHPTAITVGYSPVLHAHTAQVPVRFEQLLAKIDPRTGNITEENPQFIKTGDSAIVVLRPMKPVVLEPVKELPQLGRFAIRDMGMTIAAGMVISIQKGE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIB2_SCHPO
Sequence: MQIPEKYLSSVDNVEEETQILFALSKQKDADLGMLDSKQEQIALTIGNKPIKVKQSLQSLHQSRGSTGSVLWKTSVKVVPWLLQQSWFMNSLTPKTSILELGSGISGLAGILLSPFVGNYVASDKQLYLKKIRENLDQNNASDVEVHELDWKSTPYPKDWTFDFLDYVLFFDCIYNPHLNAHLVSCLASLAERYPGMQCLFAQELRDQETLVDFLERVRPYFEVDLIKMEEINKTSVASSTNLPPANMSLFIMKPYNHEEYMLKALNEAKKCEPTDSAFCVGAVIVQNGKIVSTGYSRERPGNTHAEECAIEKFMLKNPTDSLEGAIMYSTMEPCSKRLSKKVSCTDLIVKQKFSTVVLGSLEPDIFVKCEGVDLLKKAGIVVIEKLTFQDDCLREAVRGHPPKH
What is the function of this protein?
Involved in riboflavin biosynthesis.  Converts 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1H,3H)-pyrimidinedione 5'-phosphate (By similarity).
What are the official names of this protein?
Diaminohydroxyphosphoribosylamino-pyrimidine deaminase, DRAP deaminase, Riboflavin-specific deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LMP1_EBVC
Sequence: MERDLESAPPSAPRPPLGPPLSSSIGLALLLLLLALLFWLYIVMSDWTGGALLVLYSFALMLIIIILIIFIFRRDLLCPLGGLGLLLLMITLLLIALWNLHGQALYLGIVLFIFGCLLVFGIWIYFLEILWRLGATLWQLLAFILAFFLAIILLIIALYLQQNWWTLLVDLLWLLLFMAILIWMYYHGPRHTDEHHHDDSLPHPQQATDDSSHESDSNSNEGRHHLLVSGAGDGPPLCSQNLGAPGGGPDNGPQDPDNTDDNGPQDPDNTDDNGPQDPDNTDDNGPQDPDNTDDNGPQDPDNTDDNGPQDPDNTDDNGPQDPDNTDDNGPHDPLPHSPSDSAGNDGGPPNLTEEVANKGGDRGPPSMTDGGGGDPHLPTLLLGTSGSGGDDDDPHGPVQLSYYD
What is the function of this protein?
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation.  Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family.  LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells.  Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins.  For example, induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses.  Inhibits also host IFN-alpha-stimulated STAT2 nuclear translocation and interferon-stimulated response element transcriptional activity by interacting with and inhibiting host TYK2.  Induces SUMO expression during viral latency thereby dysregulating the host sumoylation processes.
What are the official names of this protein?
Latent membrane protein 1, LMP-1, Protein p63.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae LMP-1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: LEUD_PHOLL
Sequence: MMEKFIQHTGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFHDWRFLDDAGQKPNPEFVLNQPCYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNAFNNQLLPVKLNDTDVNELFEWVQQNKACRFTVDLEQQKVHAGNKSYDFEIDSFRRHCMMNGLDSIGLTLQHLDAIITYEQEQPVFLR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: Y2624_MYCTO
Sequence: MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKPTHPSPDDYDRDLAHAERSLREAQSAVEAAGKLVKIETDIPRGPAGPVLVEASRDAEMICVGSVGIGRYASSILGSTATELAEKAHCPVAVMRSKVDQPASDINWIVVRMTDAPDNEAVLEYAAREAKLRQAPILALGGRPEELREIPDGEFERRVQDWHHRHPDVRVYPITTHTGIARFLADHDERVQLAVIGGGEAGQLARLVGPSGHPVFRHAECSVLVVRR
What are the official names of this protein?
Universal stress protein MT2699.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: CRCB_SHEB8
Sequence: MNNLLLVALGGSIGAVFRYLISIFMIQVFGSSFPFGTLLVNVLGSFLMGVIYALGQMSHISPELKALIGIGLLGALTTFSTFSNETLLLLQEGDWLKATLNVVLNLSLCLFMVYLGQQLVFSRI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RTL1_MOUSE
Sequence: MIEPSEDSFETMMELKNPSSKQMESSEGSSNTVEETPGSSGAQAGAQAGAQAEAQAETQVEAQAEAQAEAQVEAQVEAQAGSDSGPAQEEKEPPSGPLKEMQELPTNLLQEVEEPSSGPHQEMQELPTDLLQEVEEPSSGPHQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSDPCEASSNDLPQDMEESSDDGSNQESSDGSNHELSNGSNHESSFGSNPESSDVSNLESSGGSNQESSDGSQKESSYDSNPELSDNSNQELSDNSNQESSDSSNQSSDISNQEGSEPLSEASDYSMDETINSSETQSDQDDTDLGDDEEEEEEEGGEEEGQPKNSPEEVVATMGNVISLFLRMQDLKEQQRVAERLMMQAINEGRLPSLRPFSGDRRDYHEFVVLCQMTMQNYPSMLYNDELRVKFVIRHLTDLALEWANDLVEQNSPVINNFSAFLEAMSEKFEYRQTLRVAEDAMFNIRQGNRCAADYINEFRGLIPTLGWPDEVLQAHLCQGLNEEIRHYLFRIPQPNSLDNLIVLVLQLEEKLAERRALLRLPPESRPRSVAWMDAPAPEKWRVSSWLPNEFHPDIDRDHLFLLLLVRVDPYHSVAVRALVDSGAEGNYMDERFAQEHYVELYEKPYPQIIQGVDGIPIGNEPVWLCTEPLVCVHQKHYEYIEFDILPSPNFSIVLGMKWLRTHAPEVDWMRGRCTFHSPYCLRNCFTPPPPCIALETYSISLLPGLPHTYSDLADVFNPREADDETSDQPSSDGSDDLSESEPSELQQAGDSDQSGVFYESGARETLEPVSARMQEKARQQEKAREQEEYWILYDMLTDRQDYTQMVPELFDQLHGAAWFTKLELLGIKESEMRHTVTHTEDTWRASFGFGLHQMRCYRPFTMNSYSDEGNNIVHFILKDILGLFVICHGREVLVYSMSQEEHSQHVRQVLVRFRYHNIYCSLDKTQFHRQTAEILGFNISPKGVKLNKNLMNLIVGCPVPGSRRCLQSVIDLVYPYRHFVENFAVIAAPLVRQLLSSEPYYWGEEEQEALESLKRAFRKSPVLYHPKPQNPFYLETDITGSFLSASLVQTDDETGKKSTCAFYSRPLSTMEVEYPRVEMRILPIRAAFMVWCRYLENTEEPIMILLNTEDLASLNNDRLTVLLPGHWVFFFSHFNFGVMEMPAEGDTQALFRRCWNQRGFRARFLRPLLLMSIRANLRYFDRSSETEDKEDDEEEEEEDGEEEEGEEEEDGEEEEGEEEEDGEEEEEEEEDDEEEEGEEEEDGEEEEGEEEEDGEEEEGEEEEDGEEEEGEEEGEEEEEGEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEEEEDEEEEDEEVPSMVRELLAAIPMDHILNGLLAHFSVAQIRAVVLNFFRGLLYWKSLLGVAAVLVMLRARQPLSPVPAPNLEVARPQHRHTLRLILDSTLIASSGMATAIAQLLSQMPPLVGANTLPARELAELFLGPRCWHRNALHSQPPRGMRFTPGFWLTLCEFFGVRVNPEDDVFPDPYQHRYLELHVVGDEDVVLREALQDDLQRYRQCGLHDGLQDTSQDAQDNDVQEDLFGDQEAVTFRPRNLLDPEVLDFLNNRLLYTLGTDGRLTLLSRDQVAQALTRFLAMASRMALPSPAREQARLEELSDSDDELD
What is the function of this protein?
Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta.
What are the official names of this protein?
Retrotransposon-like protein 1, Mammalian retrotransposon derived protein 1, Paternally expressed gene 11 protein, Retrotransposon-derived protein PEG11.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SECA_UREP2
Sequence: MNLISKISPQNRILNRARLIAEEVLKKEEEYEHFSDQELINKSDDIIEYLANNNPLDDKLVEALCIIREVIYRVHNKRAFKVQIIGAIIVYFGDFAEMMTGEGKTLTLVLVAYLNALYKKGVHMVTVNEYLVKVGAEFATPVLNFLNMSVGQITANMNEYEKRNNYNCDITYTTNSELGFDYLRDNMVTNYANKVQRGLWFAIVDEGDSVLIDEARTPLIISGEPQEEIGNYVKADRFVKTLYPQDFTLDPESQSVALTESGVEKAQKFFNTKNYYNFENSDIIHKVTNALRANFTFFNGREYIVKKDDDGEDIIALVDQSTGRIMEGRSYSAGLQQAIQAKEQIKIEPENLTVATITYQSLFRLYKKLAAVSGTAITEAEEFLNIYNMVVVTIPTNKPIKRIDHPDYVFDNKRTKWKYVIADVIRRHENGQPILIGTASVEDSEILHQLLERVNIPHEVLNAKNHAREAEIIACAGEYKAVTIATNMAGRGTDIKLSPESLEAGGLCVIGTERSDSRRIDNQLRGRAGRQGDIGESRFFISMEDTLFSRFATDNLAKADDKLSEDVISTKFFTRLLNNTQKKVESLNYDTRKNLIDYDHVLSNQRELIYKQRDKILISSDNKDILYRMLDSVIDDLIYQSHNKPNEDIIDIKKLIDLATQNIFYDNYLNQDEYYGLKFEQIKTKLKKDCINFFEQKEQLMTPTIFNQILSEIMISNIDEEWTKHLDITSKIREGVNLRAYEQKAPLNIYVEDSDKLFEKLKHNVAWKTVCSIGKINYVHQDYSDLNSEFIVNDNEINENNNSIDFENFNESIPTDQTIQESFDDNQSDNEDDKNNN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: KR101_HUMAN
Sequence: MAASTMSVCSSACSDSWQVDACPESCCEPHCCALSCCAPAPCLTLVCTPVSRVSSPCCQAACEPSPCQSGCTSSCTPSCCQQSSCQPACCTSSPCQQACCVPVCCKPVCCLPTCSKDSSSCCQQSSCQPTCCASSSSQQSCCVPVCCKPVCYVPTCSEDSSSCCQQSSCHPACCTSSPCQQACCVPVRCKPVCCKPICCVPVCSGASTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVCRPACCMPVSSCCAPASSCQASCCRPASCVSLLCRPACSRPAC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 10-1, High sulfur keratin-associated protein 10.1, Keratin-associated protein 10.1, Keratin-associated protein 18-1, Keratin-associated protein 18.1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 10 family.
Protein: HSLR_ECO57
Sequence: MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSKPSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMALARKLNALTMPHPDRRPDKKERRDLLRFKHGDSE
What is the function of this protein?
Involved in the recycling of free 50S ribosomal subunits that still carry a nascent chain.  Binds RNA more specifically than DNA.  Binds with very high affinity to the free 50S ribosomal subunit.  Does not bind it when it is part of the 70S ribosome (By similarity).
What are the official names of this protein?
Heat shock protein 15, HSP15.
What is the protein family that this protein belongs to?
Belongs to the HSP15 family.
Protein: VSE2_TRYBR
Sequence: KNTGRRPNYRECEMRDGECNAKVAKTAEPDSKTNTTGNNSFAIKTSTLLLAVLLF
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein ETAT 1.2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: GMPP2_ARATH
Sequence: MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM
What is the function of this protein?
Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.
What are the official names of this protein?
Probable mannose-1-phosphate guanylyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: Y3356_SHEON
Sequence: MSAVIMQQGDLLLNLYIQPKASRDQIVGLHGDELKVAITAPPIDGKANAHLSKYLAKAFKVPKSDVHILKGELGRHKQVRINAPKSVPAEISALLE
What are the official names of this protein?
UPF0235 protein SO_3356.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RXLRQ_PHYIT
Sequence: MHAYSAAVLMGLLMVAEGAYVSTTACAHSAPNPTIQRYEPESIPTRLAPNRLLREPETTEASNEDRVVSIHAGIEKLSDLIKTGVSKVHGYLNLGPSATRDQPADEILRIYKLDDGIEKALVSPNLKAMESHVKELSTKNRKSEASVIGILTSHYGDDAVAKALVTAQKTVQSDDDVKTIWRLRNAQLSSWFSSDKSVDDVFTLLKLRHDDYLALASPKMEVLDDYMKLINRVTSGQETLLNVLTKGFGGEQTMAKLLLRGKEEPQTRELATALQNALLNKWVTDKFQPESVLKKLKLDRDLMNALSDPTRHTLTSYIAVFNTRNPGKKASFIGTLSAHYGDEMVANVLIAASRNGNTRRMANQLRTDQLSDWLNNQKSADEVFSLLKLRADLPNIDGALASGKLKLLEDYIKLFNREKAGDETLLKTLTTGFDGESNLAKALLTAEINPHSNKMVVKLQGELLNQWLLKGLKPESVLKNLGLDRGMKEVLSDPNRHFLTKYIWEYNSRNRFDRTSLILTLSAHYGDDVVARALAVAKGDSGLARTAAILQRQQLEGWLSSGKSADDVFTLLRIGADDFLPLNSQNLETLEDFVWLLNLKNRRIQTNIFTVVENKFGGDVQLARAVVKALNEADERGLRDSVGIASRYRSKLFGRWFDKSIEPKDVYAMILKVNGASADALEKSIVSRYTAFYKKRLAKAFTFDSPRRL
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves.
What are the official names of this protein?
RxLR effector protein PITG_15110.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm, host cytoskeleton. Note=Associates with host microtubules.
Protein: ADF11_ARATH
Sequence: MVLHDDCKLTFLELKERRTFRSIVYKIEDNMQVIVEKHHYKKMHGEREQSYEEFANSLPADECRYAILDIEFVPGERKICFIAWSPSTAKMRKKMIYSSTKDRFKRELDGIQVEFHATDLTDISLDAIRRRIN
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers.
What are the official names of this protein?
Putative actin-depolymerizing factor 11, ADF-11, AtADF11.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NCAP_MOBVC
Sequence: MSNSKEIKSFLWTQSLRRELSGFCTNTRVQVIKDAQSLLHGLDFSEVSNIQRLMRKEKRDDSDLKRLRDLNQTVNNLVELKSSQQKNTLRVGALTSDDLLVLAADLDRLKAKVNRSERPLTGGVYMGNLTQQQLDQRKILLQLVGMGGSRVPPRGGDGIVRVWDVRNPDLLNNQFGTMPSLTLACLCKQGQEDLSDVVKALTDLGLVYTAKYPNLSDLDKLTHTHPVLGLIDGNKSAINISGYNFSLNAAVKAGASLLDGGNMLETIKVTPKNIDTILKCVLKVKRSVGMFVSDTPGERNPYENILYKICLSGDGWPYIACRTSISGRAWDNTEVDLGTNKDPINKGPPTSNKTAGAAGFNAGLTYSQMMELKDSMLQIDPTAKTWVDIEGRADDPVEIAIYQPSNGHYIHFYREPTDIKQFRQDAKYSHGIDVQDLFTTQPGLTSAVLENLPKNMVLTCQGVEDIRKLLDSQGRKDIKLIDVSMQKADARKFEHQIWDEYKHLCSMHTGIVVEKKKRGGKEEITPHCALLDCLMFEATTRNSLDIVIPRPVLSKDLVFRSATPKVIL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RL16_POLNA
Sequence: MLQPARRKYRKEQKGRNTGVATRGNSVAFGDFGLKCTDRGRLTARQLEAARRAISRHVKRGGRIWIRVFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKIVFEIVGVTEELAREAFRLASAKLPLRTTFVSRMIGQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TDA7_YEAS7
Sequence: MNSNSTIGRTTLGESDTISLSFSEPSSSLNSRSTDVVFASTSTLVPQQGSLTSLPPVSSTATPTYYSTSLTYDETLHTSIDVSSTSTLVSSTDSSSSSEQDTYSSQYDPATSSYSIITPSMSIFSSTSPMSSSSSITSEWSSLTSTTPTLSSSATSLSSSWSSLSSPSSLLVSSSLSLSLSSSYSDTKLFSFDSRSSIFSPSTPTVISPSYTYLSSISATSFQITTTSELSSSWFSTISSPSTTSNKDTTFPSSSRNTSTSFYSSSLSSTNDFSTISKSSKLSPSASSSTVSISTISVPTSSSVSSSSSKVPSNRPSSSSSSDDTTSAYSSTYTFQSLQSTTSSSIPPTTQTPSTSTISTSPIPTSSQVFNTVAISSSEDSKTIYYFYTQTYDITDSSTTFVTGLPTTIAVAKSEVTSFSAPSSTITADMSFYQHWLDGSLDNNKNQGTSKTNTGTIVGSVVGSVGGILICVLVVWFMLVRKRKAKRHFKENDSFCHEIGRRTGFPTTAQAKEASLQAQDSGSQQRNTETASANNPFSNEFNFKARGNPPPVPPPRNVTAMNGSFQNMRSNFMDQENRFSYGSSFTYSSLGSSTQGGFSTLSSNSIRLGRGLDNDISHDERNTVQNNSQGFLREII
What are the official names of this protein?
Topoisomerase I damage affected protein 7.
What is the protein family that this protein belongs to?
Belongs to the TDA7 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: RPOA_ONYPE
Sequence: MKNIKFIKPFFVEEIDENPISGKFIIKPLERGYGITVGNALRRVLLSSLPGTAIVNVKIQGVEQEFTTIPGVYEDVMTIILNLKKIVFAVDDESDDFEEKLELIAKGPQRLTASSFELPAGVKIINPDHYITTLSDDVCFHMTVTLKKGIGYVGAKDNKVHGENQVGVIAIDSLFTPVVNVSYQVEKKLGNKDELTIEITTNGALLAKEALATAASILVDHFNVLVELSQKPAHVEFVSESKKEAHNSVLDLEIEQLDLSVRLFNSLKRAGIDTVAALVKLSEKEVVKLKSLGRKSFQELKDKFLEYGLEFNDYLKEVLHHSVEEDKDKH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ATPF_GEOTN
Sequence: MLAALQTAALGAAAGHGAVNSGDIIFQLVAFILLMLLLRKFAWGPLMGVMKQREEHIANEIDQAEKRRQEAEKLLEEQRELLKQSRQEAQTILENARKLAEEQKEQIVASARAEAERVKEAAKQEIEREKEQAMAALREQVASLSVLIASKVIERELTEQDQRKLIEAYIKDIQEVGGAR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.