PharMolix/UniProtQA huggingface dataset:
Protein: RTR2_YEAST
Sequence: MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFCENEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKSAAENSSDGFFIHSMYCNNYHSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDMYSVSLLEELVGSEVPIDTVKSLITSFKDLEFDDTYKNEPLPLDVYFGQLTTDEETCIE
What is the function of this protein?
Probable RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase that regulates RNA polymerase II transcription.  May have functional redundancy with RTR1.
What are the official names of this protein?
RNA polymerase II subunit B1 CTD phosphatase RTR2, RNA polymerase II-associated protein 2 homolog RTR2, Regulator of transcription 2.
What is the protein family that this protein belongs to?
Belongs to the RPAP2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TPS1B_ASPFU
Sequence: MSSTNGSEGDHRLLIVSNRLPITIRRSEGGKYEFSMSSGGLVTGLSGLSKTTTFQWYGWPGLEVPEDELGSVKKRLKDEFNATPVFMDDKLADRHYNGFSNSILWPLLHYHPGEIVFDEGAWDAYREANLLFAKTIVKEAQDGDLIWVQDYHLMLLPELLRAELRAAGKKANKIGFFLHTPFPSSEIYRILPVRGQLLRGVLHCDLIGFHTYDYARHFLSSCSHLLGLVTTPSSVKYEGRSVAVGAFPIGIDPDKFTDGLKSPKVQNRIASLENKFQGTKLMVSVDRLDYIKGIPQKLHALEVFLQNHPEWVGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTVDYMPIHFMHKSVSFDELIALYAASDACVVSSTRDGMNLVSFEYIATQQKRKGVLILSEFAGAAQSLNGSLVVNPWNTEELARAYHEAVSMSDEQRARKFEKLYKYISKYTSAFWGKSFVAELLQCSS
What is the function of this protein?
Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process (PubMed:20439478).  The disaccharide trehalose serves as a storage carbohydrate that is mobilized during conidial germination (PubMed:20439478).  Regulates the level of trehalose as a protectant for cell integrity during thermal and oxidative stress (PubMed:20439478).
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: RL27_HAMD5
Sequence: MAHKKAGGSTRNGRDSEGKRLGVKRFGGEKVLAGTIIVRQRGTKFHPGVNVGCGKDHTLFALSHGKVKFEVKGTKNRSFVSIETE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: TRMB_PROMS
Sequence: MRQHVNPLSINFNQIERIPSLGEMFGDSKLNLHLDIGCAAGEFLFDLALVNTSWNYLGIEIREKLVKNAKLKVLESEIKNLYFLFGNANNILNDVQSELIIKNLKSISFYFPDPWFKKRHYKRRVIQPEFINILSNLLQKGTLIFIKTDVKDLFDYMDYTISNNFYFKTIDKKDFNYSESFNPNKVKTNREKYVINNQLDIFERIYIKI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL2_LACCB
Sequence: MAIIKYKPTSNGRRNMSGSDFAEITKTKPEKTLLVSQSHTAGRNAHGHITVRHRGGGHKQFYRVIDFKRNKDGMAATVKAIEYDPNRTANIALLHYEDGVKSYILAPKGLKVGDKVYSGEDVDIKVGNSLQLKNIPAGTTIHNIELKPGKGAQLARSAGVSAQLLGKDNDKYVTVKLASGEVRLILAENRATIGAVGNEQHELISIGKAGRKRWLGFRPTVRGSVMNPNDHPHGGGEGKAPIGHPSPMSPWGKKTLGKKTRDHKAKSEKFIVRHRRAK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NLTP_MAIZE
Sequence: MARTQQLAVVATAVVALVLLAAATSEAAISCGQVASAIAPCISYARGQGSGPSAGCCSGVRSLNNAARTTADRRAACNCLKNAAAGVSGLNAGNAASIPSKCGVSIPYTISTSTDCSRVN
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein, LTP, Phospholipid transfer protein, PLTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: RS15_CHLCH
Sequence: MSLTQDQKVEIIKQFGTSEKDTGKSEVQVALYTRRISDLTSHLQEHPKDKHSRRGLLMLVAKRKKILNYLKNVDIERYRKVIGELELRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CLPX_PROM3
Sequence: MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSESNRKSATASHKSGKPAPTLATIPKPQEIKNFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQGDGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLDVPFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQRRLGRNAIGFMPSDGRGRSRANRDLKASQVLHHLEADDLVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALVKQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRGIIEELMLDLMYDLPSKKNVKKFTVTRTMVDEHTGGKVLPLPANDERSHKESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL6A_YEAST
Sequence: MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLEDNTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEANLFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L6-A, L17, Large ribosomal subunit protein eL6-A, RP18, YL16.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL6 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLIC1_HUMAN
Sequence: MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK
What is the function of this protein?
Can insert into membranes and form chloride ion channels.  Channel activity depends on the pH.  Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions.  Involved in regulation of the cell cycle.
What are the official names of this protein?
Chloride intracellular channel protein 1, Chloride channel ABP, Nuclear chloride ion channel 27, NCC27, Regulatory nuclear chloride ion channel protein, hRNCC.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Nucleus. Nucleus membrane; Single-pass membrane protein. Cytoplasm. Cell membrane; Single-pass membrane protein. Note=Mostly in the nucleus including in the nuclear membrane (PubMed:9139710, PubMed:12681486). Small amount in the cytoplasm and the plasma membrane (PubMed:9139710). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (PubMed:11940526, PubMed:11551966, PubMed:14613939).
Protein: RS14Z_MYCPA
Sequence: MAKKALVNKAARKPKFAVRGYTRCNKCGRPRAVFRKFGLCRICLREMAHAGELPGVQKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RSGA_CARHZ
Sequence: MEGLVVKNYAGFYYVDTGKAIYMCKARGKFKKDNIKILTGDRVIIRELVPNSEGVIESLLPRKNELIRPPIANVDQVLLVFAFADPFPSTELIDRLLVMAYALRLEVVLVFNKFDLVNPESQKLFEYYKKILPKVVAITARGDTGIDELTDYLNQKISVLAGPSGVGKSTLINRLVPGAKLATGEVSPKIKRGRHTTRHVELIKLPFGGFIADTPGFSNLTLPEMDKLELQSYFPEFNQNRKYCYFPNCLHVKEPNCRVRELLETGEIPPFRYENYLTFLEEITSDERSS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGH_VIBVY
Sequence: MKRISLIALVTLMSGCTMLEPIETPEVVNATTVVDAVEGDKSKDESSGIVDTLRGRSDPVAGDPAWAPIHPKQQPEHYAAETGSLFSVNHLSNLYDDSKPRGVGDIITVTLDEKTNASKSANADLSKSNDSSMDPLEVGGQELKIDGKYNFSYNLTNSNNFTGDASAKQSNSISGYITVEVIEVLANGNLVIRGEKWLTLNTGDEYIRLSGTIRPDDISFDNTIASNRVSNARIQYSGTGTQQDMQEPGFLARFFNVSL
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: MINE_CUPTR
Sequence: MSILSFLLGEKKKSASVAKERLQIILAHERTGHSAPADYLPALQRELVAVISKYVKIGDQDLRVSLERQDNLEVLEVKIEIPQH
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: HIS3_POLSJ
Sequence: MNWLDEVSWDEKGLIPVIAQEASSGDVLMFAWMNREALQKTAELGQAVYYSRSRGRLWHKGEESGHLQTVHEIRLDCDNDVVLLKVTQLGHEPGIACHTGRHSCFFHLYKDGQWVVTEPVLKDPGSIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSBA_NITOC
Sequence: MTFTPSLNSGLAVYRRLLSYTRPYRWIFAASIITMAIYAATETGLAALMKPLMDGSFIERDPATIQIIPLLLIGLFVIRGGANFITQYGLKWVARRVVRDLREQMFCHLLALPARYYDQKASGQLLAKLIYDVEQVSNAATDAILTIIRDSLTILGLLAWMAYLNGLLTLIILVTAPLIALIIWWVSHRFRRISRKIQNSMGDVSQVAQETIEGHREVKIFGGQTYEAERFDQVNEQNRRQTMKMAATDAISQPVVQLIAVLGLAGVIHLATRESMLAQISVGTFISFITAMMLLLGPVKRLTKINGTLQRGIAAAQSIFGLLAETPEADRGQQSLRRARGAIRFEHLSFCYEPAKGPVLENIDLEIKPYQTIALVGHSGSGKSTLVSLLARFYETTSGRILIDEMDIQTLRLTELRRQIALVSQQIILFNDTIAHNIAYGSYQQTSKQDIIRAAEAAHAMEFINRLPDGLDTVIGEKGVLLSGGQRQRLAIARALLKDAPILILDEATASLDTEAERHIQAALETLMRQRTTLVIAHRLSTVENADQIIVLHQGQIIERGTHSQLLARESHYAGLYRLQFRHSHEHVSPLSANVGL
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATK_CYTSC
Sequence: MEEYQVYLELDISRQQHFLYPLIFREYIYGLAYGHDFNGSIFSENVDYDNKSSLLIVKRLITRMYQQNHLIISANDSKKNQFWGYNKNLYSQIISEGFAIVVEIPLSLQLNSSSEEAEIIKYYKNLRSIHSIFPFFEDKLTYLNYVSDARIPYPIHLEILVQVFRYWAKDAPLFHLLRLFLYEYCNWNNLITPKKLISTFSKSNLRVFLFLYNFYVCEYESIFLFLRNKSSHLQLTSFSVLFERIYFYGKIEHFVEVFAKDFSSTLSFFKEPFIHYVRYQGKSILASKNASLLMNKWKNYLIHLWQYHFDVWSQPRTIQINQFSERSFHLLGYFSNVRLNLSAVRSQMLENAFLIEIVMKKLETIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIDRFLRICRNLSHYYNGSSKKKSLYRVKYILRLSCIKTLARKHKSTVRAFLKRLGSEKLLEEFFTEEEEILSLVFQRASSTLQGLYRGRIWYLDIIFINDLINHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRD_CLAMS
Sequence: MYPLLFRTVLSRMDPEDAHHLASTAISLLPPSGLGWIARRLTAPDPSLAVDTLGLRFPSPFGVAAGFDKDARAVLGLGQLGFGHVEVGTVTAEAQPGNPRPRLFRLIEDRAVINRMGFNNGGAAALADRLRRLRTRRDRPVIGVNIGKTRVVAVEDAVADYVRTTRLVAPVADYLAVNVSSPNTPGLRGLQEIDLLRPLLTSIRDAADGVPVLVKIAPDLQDAEVERIAELATELGLAGVIATNTTLSRADLRTDAAVVEAAGAGGLSGAPLAPRALEVLRILRRVLPSDACIISVGGVDTADDVQSRLDAGATLVQGYTAFLYRGPLWARSINAGLARIRRPR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ERF15_ARATH
Sequence: MPPSPPKSPFISSSLKGAHEDRKFKCYRGVRKRSWGKWVSEIRVPKTGRRIWLGSYDAPEKAARAYDAALFCIRGEKGVYNFPTDKKPQLPEGSVRPLSKLDIQTIATNYASSVVHVPSHATTLPATTQVPSEVPASSDVSASTEITEMVDEYYLPTDATAESIFSVEDLQLDSFLMMDIDWINNLI
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF015.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2297_MYCTU
Sequence: MAMEMAMMGLLGTVVGASAMGIGGIAKSIAEAYVPGVAAAKDRRQQMNVDLQARRYEAVRVWRSGLCSASNAYRQWEAGSRDTHAPNVVGDEWFEGLRPHLPTTGEAAKFRTAYEVRCDNPTLMVLSLEIGRIEKEWMVEASGRTPKHRG
What are the official names of this protein?
Uncharacterized protein Rv2297.
Protein: ISPE_ACTPJ
Sequence: MTKKIILPSPAKLNLFLYITNKRADGYHELQTLFQFLDFGDDISLEVNESGEIELLNAIEGVAKEQNLIYRAAKLLQNHTACSKGAKIGVTKRLPMGGGVGGGSSNAATVLVGLNHFWQTGLSLEQLAELGLSLGADVPIFVRGFAAFAEGVGEKLVACQPRESWYVVLKPNVSISTAAVFQDPNLPRNTPKRTLSRLLSEEWTNDCEKVVRDHYFEVEDLIAELLQYATFRLTGTGACIFAEFESEAEAKAVFAHKPHNIFGFIAKGQNRSPLHQMLNLTTFPQ
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MSMO1_MOUSE
Sequence: MATNKSVGVFSSASLAVEYVDSLLPENPLQEPFKNAWVYMLDNYTKFQIATWGSLIVHEAIYFLFSLPGFLFQFIPYMRKYKIQKDKPETFEGQWKCLKKILFNHFFIQLPLICGTYYFTEFFNIPYDWERMPRWYLTLARCLGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGIEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLVPFYTGARHHDFHHMNFIGNYASTFTWWDKLFGTDAQYHAYIEKSKKLGKKSD
What is the function of this protein?
Catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, which can be subsequently metabolized to cholesterol.
What are the official names of this protein?
Methylsterol monooxygenase 1, C-4 methylsterol oxidase, Sterol-C4-methyl oxidase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MPRA_MYCS2
Sequence: MAVRILVVDDDRAVRESLRRSLSFNGYSVELAQDGVEALDAITNNRPDALILDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTVSDDSGDSQKMTFSDLTLDPVTREVTRGGRQISLTRTEFSLLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYIGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity).
What are the official names of this protein?
Response regulator MprA, Mycobacterial persistence regulator A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDOX1_STAAS
Sequence: MKFMAENRLTLTKGTAKDIIERFYTRHGIETLEGFDGMFVTQTLEQEDFDEVKILTVWKSKQAFTDWLKSDVFKAAHKHVRSKNEDESSPIINNKVITYDIGYSYMK
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme oxygenase (staphylobilin-producing) 1, Heme-degrading monooxygenase 1, Iron-regulated surface determinant 1, Iron-responsive surface determinant 1.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITRA_ALBKA
Sequence: KELLDADGDILRNGGPAYPGLMPGVERDLPASGWGLPRRTGDESCPLNVKAVR
What is the function of this protein?
Inhibits trypsin with a Ki of 0. 25 uM.  Inhibits the trypsin-like proteases in midguts of larval H. armigera, S. exigua, and P. rapae.
What are the official names of this protein?
Kunitz-type trypsin inhibitor alpha chain, AKTI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: IF1_LEGPC
Sequence: MAKEDHIEMAGTVIDTLPNTMFRVELENGHIVTAHISGRMRKNYIRILTGDKVKVELTPYDLSKGRIIFRDKG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM2D2_DROME
Sequence: MRIFYGLLAFLVARQHDAQAIQARSDKEQPQTVVSGTAVQSVVPVQAQLGSGMGPSSSSSSASSASGGAGNSAFYPLGPNVMCSFLPRDFLDCKDPVDHRENATAQQEKKYGCLKFGGSTYEEVEHAMVWCTVFADIECYGNRTFLRAGVPCVRYTDHYFVTTLIYSMLLGFLGMDRFCLGQTGTAVGKLLTMGGVGVWWIIDVILLITNNLLPEDGSNWNPYV
What are the official names of this protein?
TM2 domain-containing protein CG11103.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FUCA_META3
Sequence: MDNLKEFIKICHYLYDRKYVVGSGGNVSIKKDNLIYVTPTDSLLGFINEEDIAVVDMDGNIIKGAPTSELYMHLNIYKKRNGVNAIVHTHSLYSTALPMADKEIKLLTPESRIFLKKIGYVDYFEARSMELANEVSKKDEDVIVLKNHGIVCVGKNLMDAYLKTEVMEEISQLNYIIHSL
What is the function of this protein?
Involved in the biosynthesis of the coenzyme F420 which requires phospholactate produced via the aldol cleavage of L-fuculose 1-phosphate and the NAD(+)-dependent oxidation of (S)-lactaldehyde.  Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and S-lactaldehyde.
What are the official names of this protein?
L-fuculose phosphate aldolase, L-fuculose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: SYT3_MOUSE
Sequence: MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNELRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLAPGVGLAGLVGGGGHHLGASLGGHPLLGGPHHHGHTAHHPPFAELLEPGGLGGSEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTTQADPSTEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRGGGSGEAGAPCGRISFALRYLYGSDHLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDILEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLSSFTKGGKGLSEKENSE
What is the function of this protein?
Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain.  Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.  Plays a role in dendrite formation by melanocytes.
What are the official names of this protein?
Synaptotagmin-3, Synaptotagmin III, SytIII.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein.