PharMolix/UniProtQA huggingface dataset:
Protein: QUEA_NEIMB
Sequence: MDISDFDFTLPEKLIAQHPPEVRGSSRLLVALPDMPLQDRVFGDLPDYVEAGDVLVFNNTKVMKARLFGQKDSGGRIEALIERVLDNHTALAHIRSSKSPKPGMGLVFEGGIRAVTVGREGELFCLRFEGGETVYELLEQNGHLPLPPYIERAADADDDSRYQTVYAKYQGAVAAPTAGLHFTEELLHRLKDKGAVTAEVTLHVGAGTFQPVRVDKIEEHKMHSEWFEVPSETAAAVEAAKARGNKVWAVGTTSMRALESAARATGRLKAGQGDTDIFITPGYRFNVVDRLVTNFHLPKSTLLMLVSAFSGMGHIRAAYRHAVEREYRFFSYGDAMVLGRNEGVVR
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RETR3_MOUSE
Sequence: MEEAEGVAAAPGPASGLAFRGRRAMSGSWERDQQVEAAQRTLVEVLGPYEPLLSRVQAALVWERPARSALWCLGLNAAFWFFALTSLRFVFLLAFSLMIIVCIDQWKNKIWPEINVPRPDALDNESWGFVHPRLLSVPELCHHVAEVWVSGTIFIRNLLLFKKQNPGKFCLLSCGVLTFLAMLGRYIPGLLLSYLMLVIIMMWPLAVYHRLWDRAYVRLKPVLQRLDFSVRGYMMSKQRERQLRRRALHSERATDSHSDSEEELAAFCPQLDDSTVARELAITDSEHSDAEVSCTENGTFNLSRGQTPLTEGSEDLDGHSDPEESFARDLPDFPSINVDPAGLDDEDDTSIGMPSLMYRSPPGAGDTQVLPASRNEAALPELLLSSLPGGSNLTSNLASLVSQGMIQLALSEASQTDPSGPPPRRATRGFLRAPSSDLDTDAEGDDFELLDQSELNQLDPASSRSH
What is the function of this protein?
Endoplasmic reticulum (ER)-anchored autophagy regulator which exists in an inactive state under basal conditions but is activated following cellular stress (PubMed:34338405).  When activated, induces ER fragmentation and mediates ER delivery into lysosomes through sequestration into autophagosomes via interaction with ATG8 family proteins (PubMed:34338405).  Promotes ER membrane curvature and ER tubulation required for subsequent ER fragmentation and engulfment into autophagosomes (By similarity).  Required for collagen quality control in a LIR motif-dependent manner (PubMed:34338405).  Mediates NRF1-enhanced neurite outgrowth (By similarity).
What are the official names of this protein?
Reticulophagy regulator 3.
What is the protein family that this protein belongs to?
Belongs to the RETREG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RM02_DEBHA
Sequence: MSFIKQVGKLIRPNDYSSSIFQTSFLNNVIQVRTATKRAAGSKTNKNDSAGRRLGPKAYEGHFVKPGQIIMRQRGTKIHPGENVDIGKDHTIFAIEPGYVRFYYDPFHPLRKYVGIALRKDLNLPTPHFSPRVRRFGYEKITDPAEAEKEENHMSRKEFLQQPELEKTRQEQQNQEEQRASAFRNALSSQFNLDLSEADFQLALNRLLNISQLTNVGQTLEDAEVQSTYNYVFDLKLSCKRGEMTSEEFSNLKMHYIQFAENFDKKVTIDAQGNPCTYVTPEAKKENQNEILSKLENEFSNRVISEKDKETIFDLIMTPGIYNLSQQSYLKDRFLPSVLPTTVKETVVEDVDPKKPPKGVIVTRIFDEETKQIKVIGRTKEAYIGQTDLDKSLA
What is the function of this protein?
Component of the large subunit of mitochondrial ribosome.
What are the official names of this protein?
54S ribosomal protein L2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NQRE_CHLMU
Sequence: MWLGDYSLINLLGIFLQATFIQNILLSTFLGMCSYLACSSRLSTANGLGMSVALVLTITGSINWLIHHFVTGPHALSWLSPALANIDLSFLELITFIVVIAAFTQILELLLERFSRNLYLALGIFLPLIAVNCAILGGVLFGITRNYPFLPMVVFSLGSGCGWWLAIVLFATIREKLAYSDIPQHLQGMGISFITTGLIAMAFMGLTGIDISKPTAKSVVISDTSTNKSKTTSAQERLSSNHKA
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBL_TROMA
Sequence: SVGFKAGVKDYKLTYYTPDYETKDTDILAAFRMSPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYQIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIFFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNAIIREASKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RABL3_CHICK
Sequence: MAALDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDVRIHDYKEGTPEEKTYYIELWDVGGSVGSATSVKSTRAVFYNSLNGIILVHDLTNKKSSQNLYRWSLEALNRDVAPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIPETKRNEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFFKRWQSRFLASRKERDLEEEH
What is the function of this protein?
Required for KRAS signaling regulation and modulation of cell proliferation (By similarity).  Regulator of KRAS prenylation, and probably prenylation of other small GTPases (By similarity).  Required for lymphocyte development and function (By similarity).  Not required for myeloid cell development (By similarity).
What are the official names of this protein?
Rab-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: CRE6_PHYIT
Sequence: MIRNALLVLVFVLIGTISAATDADMTTDSGKQPSNINQLTLVSPEGKRLLRQGSVKEGGVHDATEERAFIVTPLKNSLYRILAAFGLKPQTLYVQLGIRTGMANALYNRLYHSYHRWYATYGPRVYG
What is the function of this protein?
Effector that is involved in host plant infection.  Contributes to virulence during the early infection stage, by inhibiting plant defense responses induced by both PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI).
What are the official names of this protein?
RxLR effector protein CRE6, Core RXLR effector 6.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: DU4L7_HUMAN
Sequence: MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGVSQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPLLETEAPGELEASEEAASLEAPLSEEEYRALLEEL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Double homeobox protein 4-like protein 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_LEGPL
Sequence: MSAYFRRKKMCRFSAEGGNEIDYKDINLLKNYITETGKIVPSRITGTQTRFQRQLAKAIKHARFIGLLPYCDSHR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RL28_PSEE4
Sequence: MSRVCQVTGKGPVTGNNISHANNKTRRRFLPNLQHHRFWVESENRFVRLRVSAKGMRIIDKRGIDAVLVDIRRAGAKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: F9_ORFN2
Sequence: GHAAANCALARVATALTRRVPASRHGLAEGGTPPWTLLLAVAAVTVLGVVAVSLLRRALRVRYRFARPAALRA
What are the official names of this protein?
Protein F9 homolog.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae L1 protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Note=Component of the mature virion (MV) membrane. The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis (By similarity).
Protein: NU1M_ZAEPI
Sequence: MFLMNILCLVIPILLAMAFLTLVERKILGYMQLRKGPNIVGPYGLLQPIADAIKLFIKEPLRPLTSSKLMFTLAPTLAFTLALSLWIPMPMPHSLINLNLGVLFILALSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVMMMNGSFTLSTLTTTQEHMWLILPLWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIIMMNALTATLFLGAFHNPLFPELFTVNFITKTLILTAIFLWVRASYPRFRYDQLMHLLWKSFLPLTLALCMLHVSIPALSAGVPPHM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NKD_AEDAE
Sequence: MDLGIPEFTCDVSLEDGKKPQPLQFSFTLYDLDGHGKITKDDIAGIVSTIYESIGKSVVVPHYGSKTINVRLTVSPDGKTKQTASAVKKAAITPRRRYRPRKLISDDDGSDTSENCPRVMRTRANTVVANTTINNNVKHKDNNVAKDEDVVDGLTKSSEAVETTFHNNLNGKGKTLNVKNDNIYESINNLKCCNIQAAQASKPTVALSQSPGTLNNSTATTVICRDCSLEGCTIDETLPLGTVVIPATTPAAAISSRAKRKVVRKSRSSRKASKLTDDFSRPRARSLSVGNENCYENMIGTTQEECWKSSLCRRELIEIIRDSMVKNSLCFQPNRKPLENSPKHRHRSHTIAARIGAEHCGETVMATQQALVAAHETNLCGYDSYLHQTICAAANANHAALHLNGGVVGNGGVFTALPLTTSTPNRLLQHHSHHAHAKAKRKEHRLAVATRSQVHHQVAQPVKLSTAVLNQQYPNLSAEQKLSRSINQVEKWLDNRSPKLVNKLKLAEEIAEKSPRVAAAKLKRSKSKEEITHKSTKFENVLTTDLLLDNLKITEDIAELSVVTPKKIFNKECLISSATKKNIRTHHTTKTVSTTTAVVPPAVDKASKNLIQLQYASVPINAELSECENLIRISDAEEELHQSVQQQQGTHQQQQQPQSSVSSPTHHHHHHAGASLLGENSGSSASAASTTAVHRYVHEHIHHHYHHFENDPDES
What is the function of this protein?
Cell autonomous antagonist of the canonical Wnt signaling pathway.  May activate a second Wnt signaling pathway that controls planar cell polarity.  Required for neuroblast specification (By similarity).
What are the official names of this protein?
Protein naked cuticle homolog.
What is the protein family that this protein belongs to?
Belongs to the NKD family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus.
Protein: HSCA_BURM1
Sequence: MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRNSVPEVLPDDAGRVLLPSVVRYLENGGRRIGHDAKAQAATDPRNTIVSVKRFMGRGKAEVEGAANAPYEFVDAPGMVQIRTVDGVKSPVEVSAEILATLRQRAEDTLGDELVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNAAEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDFDHALFDHVLAQAGLDAKTLAPEDVRLLLDRVRVLKEALSSAPEAALDVTLSNGAHLAQTISHDTFATLVEPLVQRTLTPTRKALRDAQVTPADIKGVVLVGGATRMPVIREAVAKYFGQPPLVNLDPDQVVALGAAIQADLLAGNRGSGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPIARAQEFTTFKDGQTAMAIHVVQGERELVADCRSLARFELRGIPPMTAGAARIRVTYQVDADGLLSVFAREQHSGVEASVVVKPSYGLADDDIAKMLEDSFKTAEVDMRARALREAQVEAERMIEATQAALAADGELLDAVERAEIDARVAALRTIAQGDDADAIEAATKALADGTDEFAARRMDKSIKRALSGRRLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YE76A_YEAST
Sequence: MASPGFHRPSGRSQHVCMRITIRSHKKMRRYSILRSFFSLGLIACFCIFLIIVLSEEPNMRLLYKLSYGYVKILNNVKLLESIASCIRCGRITSVNDLNQFVFQSTAVFFTNKTD
What are the official names of this protein?
Putative uncharacterized membrane protein YER076W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SIDA_EMENI
Sequence: MEPLQRKSELDFQSYRKMPLAQQRTQRLKPTSPEELHDLICVGFGPASLAIAIALHDALDPCLNKCAPTSGWQPKVAFLERQKQFAWHSGMLVPGSRMQISFIKDLATLRDPRSSFTFLNYLHQKDRLIHFTNLSTFLPARMEFEDYMRWCANQFSDVVTYGEEVIEVLPGKSSPDSPVVDYFTVLSRNVETGEISSRSARKVVLALGGTAKLPAELPQDPRIMHSSKYCTALPNLLKDNNEPYNIAVLGSGQSAAEIFHDLQKRYPNSRTSLIMRDTAMRPSDDSPFVNEVFNPERTDKFYNLSAAERERSLKADKATNYSVVRLELIEEIYHDMYLQRVKNPDETQWQHRILPSRKITRVEHYGPNKRMRVHVRAVKDGKDSLIGDGKEVLEVDALMVATGYNRNAHEQLLSKVQYLRPATQDRWTPSRDYRVDLDRSKVSAGAGIWLQGSNEQTHGLSDSLLSVLATRGGEMVESIFGEQLESAAVPDTRFRAML
What is the function of this protein?
Catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as the secreted triacetylfusarinine C (TAFC) involved in iron uptake and the intracellular iron storage compound desferriferricrocin (DFFC).
What are the official names of this protein?
L-ornithine N(5)-monooxygenase, OMO, L-ornithine N(5)-oxygenase, Siderophore biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.
Protein: PLSY_SINMW
Sequence: MDIFSWQLGLPSTLACLVFGYLLGSIPFGLILTRMAGLGDVRKIGSGNIGATNVLRTGNKKLAATTLLLDALKGTAAAAIASLWGVEAGMAAGLAAFLGHLFPVWLSFKGGKGVATYIGVLLGLVPVMVLLFAAAWLAVAKISRYSSLSALVATAIIPVALYATGNGKVALLFAVMTLIAWVKHRANIQRLMSGTESRIGEKG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOA_PAEAT
Sequence: MLIAQRPTLSEEVVSENRSRFIIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTEIILNIKNLSVSSEHDEPVVAYLRKQGPGVVTAADIAPPAGVEFHNPDLHIATLNSKGKFELELTIERGRGYVSAAQNKSGDSEIGRIPVDSIYSPVMKVTFRVEATRVEQRTDFDKLIVDVETKQAIAPRDAVASAGTTLVELFGLARELNTAAEGIEIGPSPTDAALAADMALPIEDLDLTVRSYNCLKREGIHTVGELVARSEADLMDIRNFGAKSIDEVKAKLVELGLSLKDSPPGFDLAARAAAIEEDDAAFSDDEL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TRPF_CLOAB
Sequence: MVKIKVCGIRREEDIEIVNKYKPNYVGFVFAKSKRQVDMYKAEKLADKLDVSIKKVGVFVNEDIEKVKEVSFRVKLDIVQLHGDENEEYIDKLKGFKVWKAVNVTAGKDVEKFKNYRIDAFLVDGYDGTNRGGTGKSFNWNLLKENQDKILKPIIAAGGLNIDNVEKCIEVLNPFAVDVSSGVETDGFKDEEKIKKFIMRVRKFK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SYGA_SYNS9
Sequence: MHFQDIIGTLNSFWANQGCLLLQPYDTEKGAGTMSPHTVLRAIGPEPWAVAYPEPCRRPTDGRYGDNPNRAQHYFQYQVLIKPSPDAIQETYLASLEALGIKAADHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGLDCKPVSIEITYGLERLAMYLQDVESIWDLSWNADRKYGDIWLPFEKGQCKFNFEASNPDRLKQLFAIYEAEASDLIHQQLPAPALDFVLKCSHTFNLLEARGVISVTERTATIGRIRNLARKVAEAWLVEREALGFPLLPSN
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CU36_MANSE
Sequence: MKLFVLAAVLGVCLADRLDNKYLPPRGNAGAGFGPGFGGAGPKGGGSGFGGAGSGFGGAGSGFGGAGSGFGGGAGGAFGHGGAGSGFGGQAGGYSGAGGAGGYSGGASGQYSGRGGAASADANAQILRLNNEVTAEGFAYDFETSNGIRADAQGVATNGVQSQGSFAYKGDDGQDYSITYTADENGFVPQGAHLPTPPPIPEEILKSLEQNARDEAAGIVDDGTYRGEGAGAGVAGGYSGAGGYSGGAGGAGGFGAGGAGRAGGAGGFGTGGAGRAGGAGGFGAGGAGGAGGAGGFGAGAGGFGGRGSGGFGGAASRQYLAPNAGGRGSGSGNFNAQTGYQY
What is the function of this protein?
Component of the pupal abdominal endocuticle.  May have important role in the larval and adult exoskeleton structure.
What are the official names of this protein?
Pupal cuticle protein 36, MS-PCP36, MsCP36.
What are the subcellular locations of this protein?
Note=Synthesized in the epidermis during the larval-pupal transformation and then secreted into the pharate pupal cuticle.
Protein: TUSA_VIBVU
Sequence: MSFNPELATKTLEAEGLRCPEPVMMVRKTIRTMQDGEVLLVKADDPSTTRDIPSFCRFMDHQLIAAQTDELPYQYLIKKGL
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_NITEU
Sequence: MDTYAVIGNPVAHSKSPFIHARFAQQTGRIIHYTALLAPLDRFEQTVLDFRKTGGKGMNITVPFKFEAFTLASRLTDRASAARAVNTFRFEETGEILGDNTDGVGLIRDIEVNLNFPLAGKRILLMGAGGAASGVILPLLQQQPDLLAIANRTPDKAVSLQRQFASYSNITTGHYHDFAGQHFDLIINATSASLHNELPPVPADLFRNAFAYDMLYSSRLTPFLELARVQGAGYLADGAGMLVEQAAESFLLWHGIRPETQTVIRQLRDNLRHPTS
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: EAA3_RAT
Sequence: MGKPTSSGCDWRRFLRNHWLLLSTVAAVVLGIVVGVLVRGHSELSNLDKFYFAFPGEILMRMLKLVILPLIISSMITGVAALDSNVSGKIGLRAVVYYFSTTVIAVILGIVLVVSIKPGVTQKVNEINRTGKTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPASDPGGNQTEVSVTTAMTTMSENKTKEYKIVGLYSDGINVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPIGILFLIAGKIIEVEDWEIFRKLGLYMATVLSGLAIHSLVVLPLIYFIVVRKNPFRFALGMAQALLTALMISSSSATLPVTFRCAEEKNHVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNGMDLSIGQIITISITATAASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQVDVSSEVNIVNPFALEPTILDNEDSDTKKSYVNGGFSVDKSDTISFTQTSQF
What is the function of this protein?
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:9011753, PubMed:11242046).  Can also transport L-cysteine.  Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion.  Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport.  Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli (By similarity).  Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).  Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport (By similarity).  Negatively regulated by ARL6IP5 (PubMed:11242046).
What are the official names of this protein?
Excitatory amino acid transporter 3, Excitatory amino-acid carrier 1, Sodium-dependent glutamate/aspartate transporter 3, Solute carrier family 1 member 1.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Synapse, synaptosome. Early endosome membrane. Late endosome membrane. Recycling endosome membrane.
Protein: MRAY_TOLAT
Sequence: MLVWLAEWLTPHLSFFHVVSYLTFRAIMSILTGLGFALWIGPRLIRRLQLLQIGQVVRNDGPESHFSKAGTPTMGGIMILLSIFLSVILWARLSNPYVWVVLFVLVSFGTIGFIDDYRKVIRKNPDGLIARWKYFWQSAAALVVAFFLYATATTDAQTVLVVPFFKDIMPQLGLLFILMTYFVIVGASNAVNLTDGLDGLAIMPTVMVAAGFALIAWATGNVNFANYLHIPYVANASELMVICTAIIGAGLGFLWFNTYPAQVFMGDVGSLALGAILGIIAVLVRQEFLLFIMGGVFVMETMSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIITLVLVLLGLVTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRE_NEIMA
Sequence: MTDFRQDFLKFSLAQNVLKFGEFTTKAGRRSPYFFNAGLFNDGLSTLQLAKFYAQSIIESGIRFDMLFGPAYKGIILAAATAMMLAEKGVNVPFAYNRKEAKDHGEGGVLVGAPLKGRVLIIDDVISAGTSVRESIKLIEAEGATPAGVAIALDRMEKGTGELSAVQEVEKQYGLPVAPIASLNDLFILLQNNPEFGQFLEPVRAYRRQYGVE
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: ARMC8_DANRE
Sequence: MACLLEAPLRISVLSEVTATSRHYVDRLFDPDPQNVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQSSSTLELRTECAVVLGSLSMGTENNIKSLVDCHIIPALLQGLLCSDLIFIEACLRCLRTVFISPVTPVQLLYTDPTVIPHLMSLLSRSQHTQEYITQIFAHCCKTPEHQTVLFNHGAIQNIAPLLISPSYKVRMQALKCFSVLAYENAQVSMTLVNVLVDGEQLSQVFVRMMQRDKPIEMQLTAAKCLTYMCRAGAIRTEDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLMEPDIELQRIASVTDHLVSMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGSNDEDIRKKITETENMMDRIVSGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFHDHAVWKPLMKLLQNAPDEVLVMASSTLCNLLLEFSPSKEPILESGVIELLCSLTQSDSSALRVNGIWALMNMAFQADQKVKVEIVRALGTEQLFRLLSDPDTNVLMKTLGLLRNLLSTRPHIDQIMSSHGKQIMQAVTLILEGEHSIEVKEQTLCILANIADGNTAKELIMTDDDMLQKIKYYMGHSNVKLQLAATFCISNLIWNEEDGSQERQDKLREMGFVDILHKLTQASDPDLCDRAKTAMQQYLA
What is the function of this protein?
Component of the CTLH E3 ubiquitin-protein ligase complex that mediates ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Armadillo repeat-containing protein 8.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.