PharMolix/UniProtQA huggingface dataset:
Protein: PSBS_ARATH
Sequence: MAQTMLLTSGVTAGHFLRNKSPLAQPKVHHLFLSGNSPVALPSRRQSFVPLALFKPKTKAAPKKVEKPKSKVEDGIFGTSGGIGFTKANELFVGRVAMIGFAASLLGEALTGKGILAQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGKFVDDPPTGLEKAVIPPGKNVRSALGLKEQGPLFGFTKANELFVGRLAQLGIAFSLIGEIITGKGALAQLNIETGIPIQDIEPLVLLNVAFFFFAAINPGNGKFITDDGEES
What is the function of this protein?
Plays an important role in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.  Is not necessary for efficient light harvesting and photosynthesis.
What are the official names of this protein?
Photosystem II 22 kDa protein, chloroplastic, CP22, Protein NONPHOTOCHEMICAL QUENCHING 4, Protein PHOTOSYSTEM II SUBUNIT S.
What is the protein family that this protein belongs to?
Belongs to the ELIP/psbS family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y966_PHOPR
Sequence: MSKKNPNLEDELSLFQDAVKGVKKFTHDTIITRRQQNSKVDKAKVSSKETQNHEFYFSDEFEPHLNEHGPTQYARTGVSKYEVKKLRRGIYVPDMYLDMHGMTQQEAKRELAAMLAACIKESVSCACVMHGIGKHILKKKAPLWLAQHPDVMAFHQAPLEFGGNGALLVLIDIPER
What are the official names of this protein?
UPF0115 protein PBPRA0966.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: MURI_SYNY3
Sequence: MREPQRSRIGVFDSGVGGLTVLRELYRQLPKESILYFGDTARLPYGKRSPQVILQYVREILTWMAAEEVKMVIMACNTSSALALETVQQEFNMPILGVILPGARAAVRQGRRIGVISTPATAASNAYRHAIHEITPDALVWQMACPEFVPLIEQNRLHDPYTLEVAKGYLQPLLDADIDTLVFGCTHYRHLTPVFQQILPSHIRLVDPASHVVKAARQELEVMGLRNSEMSIATRFTVSGCPQQFAELSHQWLGFTPMVEKISLPCLSSICPQPLEIRE
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: SUFE_ENT38
Sequence: MAALPDRDKLLRNFTRCANWEEKYLYIIELGQRLPVLSEEAHNPENIIQGCQSQVWIVMRQNDDGVIELQGDSDAAIVKGLVAVVFILYHQMSAQDIVAFDIRPWFEQMALTQHLTPSRSQGLEAMIRAIRSKAANIS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_SHIF8
Sequence: MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHDDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQASPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SG2A2_HUMAN
Sequence: MKLLMVLMLAALSQHCYAGSGCPLLENVISKTINPQVSKTEYKELLQEFIDDNATTNAIDELKECFLNQTDETLSNVEVFMQLIYDSSLCDLF
What are the official names of this protein?
Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family. Lipophilin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TATA_BACC2
Sequence: MFSNIGFPGLILILVAVLILFGPKKLPEIGKALGETLKEFKKSTKELTDDAFQEKEKKEKM
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SPIN2_PONAB
Sequence: MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKKS
What is the function of this protein?
May be involved in the regulation of cell cycle progression.  Exhibits H3K4me3-binding activity.
What are the official names of this protein?
Spindlin-2, Spindlin-like protein 2, SPIN-2.
What is the protein family that this protein belongs to?
Belongs to the SPIN/STSY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APT_METCA
Sequence: MDKLRAKIRDIPDFPKPGILFRDITPLVKDPAALRLAIHQLVHPFVGEDITAVAGMEARGFIFGALAAWELGVGFVPLRKPGKLPYNVQSIDYDLEYGSARLEVHLDALGVGDRVLMVDDLLATGGTARASCSLVESLGAEVAACAFVIELDALEGREALHGRRVHSLLHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_SALRD
Sequence: MPLDATTQLVTLLGHPVEHSLSPRIHNTAFRAQDVNAAYVATPVRPEALGDAVAGLRALQFLGANVTTPHKEAVLPVLDEVTERARAVGAVNTIVRDGGRLHGDNTDIAGFLRPLEERGGDALEGAPMLVFGAGGAARAVVYGLLSHYRPERLTIVARRPDQAEGLAADLAAHDPDGALRVSSFEEAALSVRTSRLVVNATPLGMAPDRRGQTPWPNPVDFTADHVVYDLVYTPEETRLLREAAAEGATPIGGLDMLVEQAAAAYRQWTDRGMPQAAVYDALRAD
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MUTL_SYNFM
Sequence: MARITILPDILCNQIAAGEVVERPAAVAKELLENSIDAGARRISLSIADGGRKEIRVVDNGSGMHPDDALLALERHATSKIRSIEDLQAIGSLGFRGEALPSIAAVSRFELVTREPDAVAGTFIRVEGGVVREVRETGSPAGTRITVRDLFYNVPARRKFLRAADTETAYICDQFQRLAMAHHAVHFQLINRERTQYDFPGAASPEERAGQVLGAETLKRAIPFCVENASARLRGMVGTPDLQRANSHSLFVFVNGRPVWDRAVNRAILAAFESLIPRGKFPVAVLFLELDPLHVDVNVHPTKREVRFKHPGGVIDTVRGAIRDALCHLRPLHGSAAAAPRPFSETADQRAFRDSLVREGQLSFDRGRPLSRPPGFPSERWRERHRPDAEPPYPLLREPAPTENPRREAGSPPAAPADSLFDEGAAPQPDNPDTDFFAEPKRAAGGPASTHAPVTVDTAAFADAFQAFEAATHLHAGDVPALAELPVIGQLANTYILLEAPDGLILIDQHAAHERIIFDALSFPAGGPARQRLIRPAVIDLPPRDAAMLRRWLPLLEEIGVEIESFGGDSFVVHAVPAPLGECPPEGLVRELLASAIEGDDAPRWNVLGRLAKTAACHRAVRAGQRLRPEEIRLLLEGLDRTRFASTCPHGRPVWYKMTLSDVARLFQRT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SMC_MYCLE
Sequence: MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGEQGAKTLRGSKMEDVIFAGTLSRAPLGRAEVTLIIDNSDNVLPIEYSEVSITRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDQILQSRPEDRRTFIEEAAGILKYRRRKEKALRKLDAMSANLARLTDLTTELRRQLKPLSRQAEVARRAATIQADLRDARLRLAADDLVSRQGQRDAIVEAETMMRRDHDEAAARLAVASEELAAHEAALTELSGRAESVQQIWFGLSTLVERVSATIRIAGERAYHLDVDPATPSDTDPDVLEAEAQQMEVAEQQLLAELAVARTQLEAARAELADRERHAVEADKAHLEAVRAEADRREGLALLAGQVETMRARIESIDDSVARLSERIEEVTARTQQILAEFETVQGRVGELDQSEVHLDEQHERAVAALRFANERVAELQSAERDAERQVVSLRARIDALTMGLERKDGAAWLARNYSDTGLLGSIAKLVKVRPGYEAALAAVLGPAADALAVDSLGAARSALTALKEADAGRATLVLADWLADAGPACVTGLPDGAQRALDLIEAPPWLQGALIAMLYGVVVVNYLAEALGVVDICPQLRVVTVDGDLVGAGWVSGGSGRRLSTLEVTSEIDKAGAELAAAEAHMAQLNAALSGALSEQVAHSDATEQALVALNESDTAILSMYDQLGRLGQEVRAAEAEWESLLAQREELEARRVSILEEVVELETRLHNVEQIQHVHALDENSAAARQLIVAAAEEARGVEVEALLAVRTAEERVNAVCGRANSLRRAAAAEREVRLRDQQAHAARIRAAAVAAAVTDCGQLLASRLTQAVDLAARHRDALATERQQRSVAIAAVRYEVNTLRVRLATLTDSLHRDEVANVQAALRIEQLEQLVLEQFGIAPVDLIAEYGPQVALLPTELEMAEFQQARERGEQVTSPAPMPYDRATQERRAKRAERELAELGRVNPLALEEFAALEERYNFLSTQLEDVKGARKDLLDVVAEVDARILQVFSDAFVDVEREFRGVFTSLFPGGEGRLRLTDPDDMLTTGIEVEARPSGKKVSRLSLLSGGEKSLIAVAMLVAIFKARPSPFYIMDEVEAALDDVNLCRLIGVFEQLRGQSQLIIITHQKPTMEVADTLYGVTMQGDGITAVISQRMRGQQVESLVTSSS
What is the function of this protein?
Required for chromosome condensation and partitioning.
What are the official names of this protein?
Chromosome partition protein Smc.
What is the protein family that this protein belongs to?
Belongs to the SMC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBP2_STRP2
Sequence: MRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNNAVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSNTYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYHPMN
What is the function of this protein?
A transpeptidase that forms peptide cross-links between adjacent glycan strands in cell wall peptidoglycan (PG).  Part of the elongasome machinery that synthesizes peripheral PG.
What are the official names of this protein?
Penicillin-binding protein 2B, PBP2b.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Localizes to the midcell division sites, colocalizes with StkP.
Protein: EFEB_SHIFL
Sequence: MQYKDENGVNEPSRRRLLKGIGALAGSCPVAHAQKTQSAPGTLSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLSQGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVNHALRDIIKHTPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLANPRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEEYVKPIGGGYFFSLPGVKDANDYLGRALLQV
What is the function of this protein?
Involved in the recovery of exogenous heme iron.  Extracts iron from heme while preserving the protoporphyrin ring intact.
What are the official names of this protein?
Deferrochelatase, Peroxidase EfeB.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family. EfeB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ALS6_CANAL
Sequence: MKTVILLHLFFYCTIAMAKTISGVFTSFNSLTYTNTGNYPYGGPGYPTWTAVLGWSLDGTLASPGDTFTLVMPCVFKFITTQTSVDLTANGVKYATCTFHAGEDFTTFSSMSCVVNNGLSSNIRAFGTVRLPISFNVGGTGSSVNIQDSKCFTAGTNTVTFTDGDHKISTTVNFPKTPQSSSSLVYFARVIPSLDKLSSLVVASQCTAGYASGVLGFSATKDDVTIDCSTIHVGITNGLNSWNMPVSSESFSYTKTCTPNSFIITYENVPAGYRPFIDSYVKKSATATNGFNLNYTNIYNCMDGKKGNDPLIYFWTSYTNSDAGSNGAAVVVTTRTVTDSTTAITTLPFDPTVDKTKTIEVIEPIPTTTITTSYVGISTSLSTKTATIGGTATVVVDVPYHTTTTITSIWTGSATTSSTYTNPTDSIDTVVVQVPSPNPTVTTTQFWSGSVPTTETVTTGPQGTDSVIIKEPHNPTVTTTEFWSESFATTETVTNGPEGTDSVIVREPHNPTVTTTEFWSESFATTETVTNGPEGTDSVIVREPHNPTVTTTEFWSESFATTETITTGPLGTDSIVIHDPLEESSSSTAIESSDSNISSSAQESSSSVEQSLTSADETSSIVELSSSSDIPSSSIGLTSSESSTVSSYDSYSSSTSESSIASSYDSYWSSSIESSTLSSSDRYSSSISDTTSFWDSSSSDLESTSITWSSSIDAQSSHLVQSVSNSISTSQELSSSSSEESSTSATDALVSSDASSILSSDTSSYYPSSTISPSDDFPHTIAGESDSQSISFITSTVEISSDSVSLTSDPASSFDSSSSLNSDSSSSPSSDQSDILTSSSFSTLVVPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKLSVFVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELTTTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDGESTVEIPPVTDTTTVSSVSVHSIEASTATLGENSFSKVASAPVNTETSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGSTYANSGSTNNLMTESQVAAPTDSTSVLTANPVVTSTFDDKSSAAVNQPSKTKSIEESIGSLDSVNETNNGFIATLSQSEAPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
What is the function of this protein?
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation.  Plays an important role in the pathogenesis of C. albicans infections.
What are the official names of this protein?
Agglutinin-like protein 6, Adhesin 6.
What is the protein family that this protein belongs to?
Belongs to the ALS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently- linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer.
Protein: ADD_SHEB9
Sequence: MIDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQGKETSLVAFLKKLDWMVGVLADLDAVKRVAYENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVVDGVKAGLKDYNVKINLIGILSRSFGQAACTQELEGLLTHKQHLVAMDLAGDEMGFPGELFNEHFKRVRDADLAITAHAGEAAGSQSMWQAIQELGATRIGHGVNAIHDPKLMEYLAKHRIGIESCPTSNLHTSTVASYADHPFRTFMDAGVLINLNTDDPGVSAIDINHEYRIAKSELKLTDAELAQVQRNGVEMAFLSDSERKALYAAKV
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: RECR_RHOPT
Sequence: MAGAAGPEIERLIQLLARLPGLGPRSARRAALHLIKKRDALMAPLASALQVAIDKIEVCSTCGNIDSQNPCTVCTDPRRDSSIIVVVADVADLWALERASATNGRYHVLGATLSPLDGVGPEDLTIDALVKRAHDPGVAEIILALNATVDGQTTAHYVTDLLQDANVKVTRLAHGVPVGGELDYLDEGTLSAAMRQRTLF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PTLI_BORBR
Sequence: MIHAHSNARLLRWAILAIAPATLGACAPNGPPGLPYPDGKPLIPINTAAPEQGSSCQTRAP
What are the official names of this protein?
Type IV secretion system protein PtlI homolog.
Protein: PUR9_STAA2
Sequence: MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: QSOX1_HUMAN
Sequence: MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAARQNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEGPEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLSFMGLLAMYTYFQAKIRALKGHAGHPAA
What is the function of this protein?
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:17331072, PubMed:18393449, PubMed:23704371, PubMed:30367560, PubMed:23867277).  Plays a role in disulfide bond formation in a variety of extracellular proteins (PubMed:17331072, PubMed:30367560, PubMed:22801504, PubMed:23867277).  In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration (PubMed:23704371, PubMed:30367560, PubMed:23867277).
What are the official names of this protein?
Sulfhydryl oxidase 1, hQSOX, Quiescin Q6.
What is the protein family that this protein belongs to?
Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
What are the subcellular locations of this protein?
[Isoform 1]: Golgi apparatus membrane; Single-pass membrane protein. Secreted. Note=A small proportion is secreted, probably via a proteolytic cleavage that removes the membrane anchor. SUBCELLULAR LOCATION: [Isoform 2]: Secreted. Note=Found in the extracellular medium of quiescent cells but is not found in proliferating cells.
Protein: SPSB3_HUMAN
Sequence: MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIPSAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLPLPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
What is the function of this protein?
May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
SPRY domain-containing SOCS box protein 3, SSB-3.
What is the protein family that this protein belongs to?
Belongs to the SPSB family.
Protein: Y1352_STAAM
Sequence: MQIELTDAAVTWFKNELELPENNKVLVFFVRYGGEFQLKQGFSPAFTVEPKEDVDIGYEQQYDDLNVVVAEKDLWYFEDDHIIVNVVDHEDEISYSTK
What are the official names of this protein?
Uncharacterized protein SAV1352.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PLSY_UREU1
Sequence: MDQVYSVAMAYILTLIISPLYSYLIGSLNASIILSLLLKKQDIRHFASKNAGMTNMTRVYGKKLGILTLFLDIVKPIITISLTYIIYKYALNAPFVLSNGFNQAILVYFGGIFTIIGHCYPIFFKFQGGKGVASYGGFLITIDPIVAVIGIITLLIILLITKYMSLSAMITATITCFLVLIPGINYIPYYNEHFVEYLFDLNHVIKGTWYVWLFLLISASILIYRHKTNILSIATKQERKTFLFQPKPKNNI
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH60_STAHJ
Sequence: MAKDLKFSEDARQAMLRGVDKLANAVKVTIGPKGRNVVLDKEYVAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLREGIDKAVRVAVQALHDISQKVENKNEIAQVGAISAADEEIGKYISEAMDKVGNDGVITIEESNGLDTELEVVEGMQFDRGYQSPYMVTDSDKMIAELERPYILVTDKKISSFQDILPLLEQVVQSSRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGATVITDDLGLELKDASIDMLGSANKVEVTKDNTTVVDGDGDDNSIDARVSQIKAQIEETDSDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNIYNKVDEIEAEGDVATGVNIVLKALSAPVRQIAENAGLEGSVIVERLKHADAGVGFNAATNEWVNMLEEGIVDPTKVTRSALQHAASVAAMFLTTEAVVATIPEPDNNDNPGMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED7_HUMAN
Sequence: MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKTEPMDADDSNNCTGQNEHQRENSGHRRDQIIEKDAALCVLIDEMNERP
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, hMED7, Activator-recruited cofactor 34 kDa component, ARC34, Cofactor required for Sp1 transcriptional activation subunit 9, CRSP complex subunit 9, Mediator complex subunit 7, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVB_DELAS
Sequence: MSIHTDDFGQGGFAQGGFPPDKAPDKLRMISAAPVSRGEEAMERALRPKLLQEYVGQAKAREQLEIFIGAARKRNEALDHVLLFGPPGLGKTTLSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTAEELARIVRRSAGLLNAPIDDEGAFEIARRSRGTPRIANRLLRRVRDYADVRGDGSITRELADRALAMLDVDPQGFDIMDRKLLEAVVHRFDGGPVGLDNIAASIGEEAGTIEDVIEPYLIQQGFLQRTPRGRMATQAAYRHLGLPVPGDDAS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.