PharMolix/UniProtQA huggingface dataset:
Protein: RL35A_BOVIN
Sequence: MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKITRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for the proliferation and viability of hematopoietic cells.
What are the official names of this protein?
60S ribosomal protein L35a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPM3_HUMAN
Sequence: MPEPWGTVYFLGIAQVFSFLFSWWNLEGVMNQADAPRPLNWTIRKLCHAAFLPSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
What is the function of this protein?
Calcium channel mediating constitutive calcium ion entry.  Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation.  In addition, forms heteromultimeric ion channels with TRPM1 which are permeable for calcium and zinc ions (PubMed:21278253).
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member 3, Long transient receptor potential channel 3, LTrpC-3, LTrpC3, Melastatin-2, MLSN2.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NS1A_HASV5
Sequence: MAHGEPYYSSKPDKDFNFGSTMARRQMTPTMVTKLPKFVRNSPQVYDWIVRGLIFPTTGKTYFQRVVVITGGFEDGTYGSFAFDGREWVEIYPIEHLNLMSSLKLIHKANALQERLRLSQEEKATLTLDVQFLQHENVRLKELISKPEPRKIQMKWIIVGAVLTFLSLIPGGYAQSQTNNTIFTDVIAACKYSTETLTENLDLRIKLALANITISDKLDAVRQILNFAFVPRSHWLRTVFYYIHYYEMWNIFMFVLAIGTVMRSTRPGTDLITLATSHLSGFRMAVLPTIPFHTTMTLWVMNTLMVCYYFDNLLAITMAILAPILGIIFLCFMEDSNYVSQIRGLIATAVLIAGGHACLTLTGTTTSLFVVILTCRFVRMATIFIGTRFEIRDANGKVVATVPTRIKNAAFDFFQRLKQSGVRVGVNEFVVIKPGALCVIDTPEGKGTGFFSGNDIVTAAHVVGNNTFVNVCYEGLMYEAKVRYMPEKDIAFITCPGDLHPTARLKLSKNPDYSCVTVMAYVNEDLVVSTAAAMVHGNTLSYAVRTQDGMSGAPVCDKYGRVLAVHQTNTGYTGGAVIIDPADFHPVKAPSQVELLKEEIERLKAQLNSAAENPSTVITQQPTATLEQKSVNDSDVVDLVRTAMEREMKILRDEINGILAPFLQKKKGKTKHGRGRVRRNLRKGVKLLTEEEYRELLEKGLDRETFLDLIDRIIGERSGYPDYDDEDYYDEDDDGWGMVGDDVEFDYTEVINFDQAKPTPAPRTTKPKPCPEPEAETQPLDLSQKKDKQLEHEQQVVKPTKPQKNDPQPYSQTYGKAPIWESYDFDWDEDDAKFILPAPPRLTKADEIVLGSKIVKLRTIIETAIKTQNYSALPEAVFELDKAAYEAGLEGFLQRVKSKNKAPKNYKGPQKTKGPKTIIH
What is the function of this protein?
Protein covalently attached to the 5' extremity of the genomic and subgenomic RNAs.
What are the official names of this protein?
Non-structural polyprotein 1A.
What is the protein family that this protein belongs to?
Belongs to the astroviridae polyprotein 1A family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: PAX4_MOUSE
Sequence: MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRALQEDQSLHWTQLRSPAVLAPVLPSPHSNCGAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGASQDLTVPKNSPGIISAQQSPGSVPSAALPVLEPLSPSFCQLCCGTAPGRCSSDTSSQAYLQPYWDCQSLLPVASSSYVEFAWPCLTTHPVHHLIGGPGQVPSTHCSNWP
What is the function of this protein?
Plays an important role in the differentiation and development of pancreatic islet beta cells.  Transcriptional repressor that competes with PAX6 in binding to a common element in the glucagon, insulin and somatostatin promoters.
What are the official names of this protein?
Paired box protein Pax-4.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNME_BORRA
Sequence: MSRLFQKEDDIVALATPFFSSALCVIRSSGVSAIEKFSTMFSDPSKLLEASGHTIHYGYILDNETKEKLDEVVVCLYRAPKSFTGQDSIEVMAHGSLIGIRRIIDFFLKVGFRMAEPGEFTLRSFLAGKLDLTKAEAINELISAKTRQVHALAVNKLSGSLFDKIDLIKKDILNFLSAISVYLDYETDDNEVVIPVDIILKSKSELERLIDSYDTARKLENGVTLVLAGSVNVGKSSLFNLLLKEDRAIVSSYAGTTRDYIQASFEFDGILFNVFDTAGLRETSDFVEQLGIVRSNSLIKEASLIFYVVDLSGKLTDDDLKFIDAYKEDSRVLFVLNKVDLEQNNQTVEFFNSNDIVSLNTVKISTKTLFGINSLYDRIRSFIAVDYMKTSDYDIVISSTRQAALLKRAYALIIELLSKIEQNISYDMLAFDVYEVVNVLGEITGEVTSDDVLNNMFKNFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_BURP1
Sequence: MSASAVNVTPGRNVVVVGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLIIGGKKTILRLIPSGIMREGVACYIGNGVVLSPEALFKEIGELEEAGLSVRERLFISEATTLILPYHIAIDQAREARRGAGKIGTTGRGIGPAYEDKVGRRALRVQDLFDARTFADRLRENLDFHNFVLTQYLGGAAVDFQATLDTMLGYADRLKPMVTDVSRRLYEENHAGRNLLFEGAQGTLLDIDHGTYPFVTSSNCVAGAAAAGAGVGPQKLDYILGITKAYCTRVGSGPFPSELYDADNPSRQDQIGITLANVGKEFGSVTGRPRRTGWLDAAALRRSIQINGVSGLCMTKLDVLDGLDEVKLCVGYKIDGEDVDLLPRGAAEVARCEPVYETFGGWKESTVGIDSWDALPANARAYLTRVQEVAGVPIDMVSTGPDRDETILLRHPFKV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_HALS3
Sequence: MDGRAVAPAAGTVLNALATGVGAAFALDIDTEASVSVTPSESGVSGEIAGHPEADTALVERCVSRVIDRYGDGQGGHVRTESEVPLAAGLKSSSAAANATVLATLDALGVADEVDRVDAARLGVQAARDAGVTVTGAFDDAAASMLGGVAMTDNREDDLLFRDAVEWHAAVWTPPERAYSADADVARCERVSGLAEHVAALAAAGDYGTAMTVNGLAFCAALDFPTAPAVTALPHAAGVSLSGTGPSYVAVGDEDGIEEVSTRWHENPGTVRETTTQLAGARTT
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY1_CHICK
Sequence: MATEGDKLLGGRFVGSTDPIMEILSSSISTEQRLTEVDIQASMAYAKALEKASILTKTELEKILSGLEKISEESSKGVLVMTQSDEDIQTAIERRLKELIGDIAGKLQTGRSRNEQVVTDLKLLLKSSISVISTHLLQLIKTLVERAAIEIDIIMPGYTHLQKALPIRWSQFLLSHAVALTRDSERLGEVKKRITVLPLGSGALAGNPLEIDRELLRSELDMTSITLNSIDAISERDFVVELISVATLLMIHLSKLAEDLIIFSTTEFGFVTLSDAYSTGSSLLPQKKNPDSLELIRSKAGRVFGRLAAILMVLKGIPSTFSKDLQEDKEAVLDVVDTLTAVLQVATGVISTLQVNKENMEKALTPELLSTDLALYLVRKGMPIRQAQTASGKAVHLAETKGITINNLTLEDLKSISPLFASDVSQVFSVVNSVEQYTAVGGTAKSSVTAQIEQLRELLKKQKEQA
What is the function of this protein?
Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles.
What are the official names of this protein?
Delta-1 crystallin, Delta crystallin I.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
Protein: RBFA_GLAP5
Sequence: MAREFSRADRVAQELQKEIAIILQREVKDPRIGMVTVSDVEISRDLAYAKVFVTFLFDSDESAVERGLEGLNKASGYIRTLVGKAMRLRIVPELRFVYDQSLVEGMRMSNLVTNVIRKDQERYVEEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHMA_ECOBW
Sequence: MNALLSNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRIKGSY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde.
What are the official names of this protein?
2-keto-3-deoxy-L-rhamnonate aldolase, KDR aldolase, 2-dehydro-3-deoxyrhamnonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily.
Protein: RECU_STRPG
Sequence: MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDYYLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAKETRQKTAMPMKNFHLHQIEHMTCVLHQKGICFVLLHFSTLKETYYLPAQALISFYQIDNGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_TOLAT
Sequence: MDAHQKQSLPAVTLAAIGVVYGDIGTSPLYTFKECFSPHIGLPPTQQVVYGFLSLIFWALILVVSVKYLAFVLRADNRGEGGILTLMSLAGRNTYAGTTTVLLVLGLIGGGFFYGEVVITPAMSVLSALEGLSVATPALTPYILPVAIAVLTALFVIQKHGTGSVGKLFGPVMLLWFFSLGTLGAISIFKNPQVLAALNPHWAIQFFLTYKTVAFFSLGSVVLAITGVEALYADMGHFGKFPIQLAWFTVALPALLLNYFGQGALILSNPEAIANPFFMLAPEWLVFPMVILSTMATVIASQAVISGVFSLTRQAVRLGYLPGMNILHTSEVEAGQIYIPFVNWMLYIAVLIVVVTFRESTNLAAAYGIAVTGTMVITTILACTVAHYNWDWPRRVVKIILISLLLIDVPLFLANVVKFFAGGWLPVMLGAIMFMVMATWKWERFLLLRQLSRMSMPLESFVAMVEKETPQKVPGTAIYLSRTQQGIPHALLHNLNHNHVLHERIVLMTFRTQDVPYVDPDQHIEIKSLSPNVWRISATYGFHETPDVYEVFRRCAMKGMAFNLNTTSFFLSRETLLPSHRSILARLRAALFIWLSKNSLRTNDFIHVPADRVVEMGVQVEV
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRK_LACLM
Sequence: MSQLQEMMTVVSQREVAYNIFEMVLKGTLVDEMDLPGQFLHLAVPNGAMLLRRPISISSWDKRAKTCTILYRIGDETTGTYKLSKLESGAKVDVMGPLGNGFPVAEVTSTDKILIIGGGIGVPPLYELAKQLEKTGCQMTILLGFASENVKILENEFSNLKNVTLKIATDDGSYGTKGHVGMLMNEIDFEVDALYTCGAPAMLKAVAKKYDQLERLYISMESRMACGIGACYACVEHDKEDESHALKVCEDGPVFLGKQLSL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrDB subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCSB_BACCR
Sequence: MSLDKIMNEAISPWMKGDGPDSDIVLSSRIRLARNFKQYQFSTMQNEEEAQKVQELFKKKFINKAVEPFGKFGLLKMNELTPLQRRVLVEKHLISPNLAGTEYGACLLSESEHISVMLNEEDHIRIQCLFPGLQLSKALQSANQIDNWIEKEVEYAFDESLGYITSCPTNVGTGLRASVMIHLPGLVLTKRISRIIQVIQKLGLVVRGIYGEGSEALGNIFQVSNQMTLGKSEEDIIADLKSVMQQIIQQEKLARELIVQNSSIELEDKVYRSYGILANSRLIQSAEAATCLSDVRLGIDLGYIKGISRNILTELMVLTQPGILQQYAGGPLGPEERDYRRATLIRERLRIEKN
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in a large number of proteins.  Is part of the bacterial stress response system.  Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: POA1_DEBHA
Sequence: MIKYIKGDLFTHTPSSRSAISIFAHACNCRGSWGGGIATVFYRKFPSAYKIYADYCSTHADDPSKLLGTTLLIPSSSSDPGNENGQKIVYVACLFTSDFYGKKKLTPGDIAANTDLSMKDLDTQLESLKEEKEIESTDQGEVVVNMPKINAGLFAVPWEITEDVLNKFNNLHINVYVVD
What is the function of this protein?
Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
ADP-ribose 1''-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the POA1 family.
Protein: PSBN_GUIAB
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYM_CHLL2
Sequence: MQHVTRTLVTTALPYANGPVHLGHLAGVYLPADIYVRYKRMKGEDVIHIGGSDEHGVPITITAEKEGISPQDVVDRYHRMNSEAFRKCGISFDYYGRTSSQGHHDTAKEFFLEIERKGIFRRKTEKLFFDAKAERFLSDRYVTGTCPICNNPEANGDQCEQCGTHLSPTELLNPKSKLSDATPELRDTMHWYFPLGRFQEALEAYVASHEHDWRPNVVNYTRTWLKQGLNDRAITRDLSWGIQVPLDDPEACGKVLYVWFDAVLGYISFTRQWAAEAGDESLWRAYWQDPESRVVNFIGKDNVVFHTLMFPAILMAWNEGRQSGIYNLADNVPASEFMNFEGRKFSKSRNYAVYLGEFLEKFPADTLRYSIAMNYPENKDTDFSWQDFQNRTNGELADTLGNFIKRSVDFTNSRFDGVVPFSCTDDDWNVLGIDWSQTIEKLDQAYEQFHIRETASLGMDIARSANRFLTESEPWKVIKTDREAAAKTMALSLNLCYALAITLYPVIPETAGRIYAMLGFEGSIDARIKRGVSAIEELLAPQLHKGHRIRKESEILFTKIEDADIEPELKKIEKLLADAEKLEAAALSQEMTFKPEISFDDFLKVDLRVATVLGAEKVKKAGKLLKLQLKVGTEARQVLAGIAQFYSPEEMVGKQVVLVANLAERTIRGEISQGMILAVEGADGRLCVVEPVGDEINGQQIQ
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUF3_DANRE
Sequence: MAAVRHLCQRTAIRLRLTCSPQSRVCVVRGHRLGPFDDEQYRKTSVSIMQKEASAGTVIYSYSPRGFNINGNTVFGPCAVLPPAILQWNVGSHSDISVESLSLFYLLEPQIEVLVLGTGARTERLHAEVLEELKKRGIAVEVQDTPNACATFNFLSSEKRLAAAALIPPPAGSR
What is the function of this protein?
Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion inner membrane.
Protein: PCKA_RHIL3
Sequence: MEMFGVHNPAIELATVGLGGAASVRYNFSAAALYEEAIRRGEAELTAQGALRAITGQHTGRSPRDKFVVRDINTDGEIWWDNNKPISPEHFAVLRDDMLAHAAGKELFVQDLVGGAEEGHALPTRVVTEFAWHSLFIRNLLIRPDTAALSSFVPKLTIIDLPSFKADPARHGCRSETVIACDLTNGLVLIGGTSYAGEMKKSVFTVLNYLLPAKGVMPMHCSANVGPDGDAAVFFGLSGTGKTTLSADPARTLIGDDEHGWSENGIFNFEGGCYAKTIRLSAEAEPEIYATTQRFGTVLENVVLNESREPDFNDGSLTENTRCAYPMDFIPNASKTGRAGHPKTIIMLTADAFGVMPPIARLTPDQAMYHFLSGYTAKVAGTEKGVVEPEATFSTCFGAPFMPRHPAEYGNLLKELIGRHGVQCWLVNTGWTGGAYGTGKRMPIKATRALLAAALSGELGQVEFRADTNFGFAVPVSVHGVDGSILDPRSTWADKAAYDAQAEKLVSMFIANFAKFENHVDGGVRDAAPGVKVAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGT_PECAS
Sequence: MKIKQAIDKIPGGLMLVPLFLGAFCNTFTPGAGKFLGSFSNGLITGTIPILAVWFFCMGASIELKATGSMLKKSGVLVVTKLATAWVVAMIAGAFLPGDGIQNGLLAGISVLALVAAMDMTNGGLYAALMNQYGSKEEAGAFVLMSLESGPLMTMVILGASGIATFEPQLFVGAVLPFLIGFTLGNLDPDLRKLFGNSVQTLIPFFAFALGNTINLSVILQTGFAGIFLGVLVIIVTGIPLILADKFIGGGNGTAGIAASSSAGAAVATPLLIANMAPEFAPVAQQATALVATSVIVTSVLVPIITALWAKRFSPKHA
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL6_ZYMMO
Sequence: MSRIGKKPVAIPTGVTANIADGVLSVKGPKGELSMPLSSEVTYSLEDGQLSVQPVNDTKRARSFWGMQRTLVQNLIDGVTQGYSKTLQITGVGYRAASQGKTLKLQLGYSHDIDFAIPEGITIQTPEPTTVNISGIDKQKVGQVAAEIRRWRRPEPYKGKGIKYAGEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YGV4_YEAST
Sequence: MNGTDILRFLQSSPTISYSKHFILITACPLFVLGLLLLGLRTAMFKQVRGKTTTSRNRGVIAAKLLVAWYLATIVMYIAKSEMWKYAFAVSLLLNSLALFF
What are the official names of this protein?
Uncharacterized protein YGL204C.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Protein: UFM1_ARGMO
Sequence: MSKITFKITLTSDPKLPFKVLRVPENTPFTAVLKFAAEEFKVPPATSAIITDDGIGINPSQTAGDIFLKHGSDLRLIPRDRVGLRWTR
What is the function of this protein?
Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins.
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
Protein: RHOA_BOVIN
Sequence: MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLVL
What is the function of this protein?
Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.  Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such as cytoskeletal dynamics, cell migration and cell cycle.  Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.  Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis.  Plays an essential role in cleavage furrow formation.  Required for the apical junction formation of keratinocyte cell-cell adhesion.  Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly.  The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex.  It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.  In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.  Regulates KCNA2 potassium channel activity by reducing its location at the cell surface in response to CHRM1 activation; promotes KCNA2 endocytosis.  Acts as an allosteric activator of guanine nucleotide exchange factor ECT2 by binding in its activated GTP-bound form to the PH domain of ECT2 which stimulates the release of PH inhibition and promotes the binding of substrate RHOA to the ECT2 catalytic center.  May be an activator of PLCE1.  In neurons, involved in the inhibition of the initial spine growth.  Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling.  Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity).
What are the official names of this protein?
Transforming protein RhoA, Gb, p21.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex. Midbody. Cell projection, lamellipodium. Cell projection, dendrite. Nucleus. Note=Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in an activated form and in a myosin- and actin-independent manner.