PharMolix/UniProtQA huggingface dataset:
Protein: LCL3_FUSV7
Sequence: MVWPFGSQSSDKGNEGKPQEQTKRSAVSWTRSLGSPDPDPFAAAKEWAPTVLFSLTGLAALQLYANYLRRIPGAAYVRPNFFRNRSLFGRVTSVGDGDNFHFFHTPGGRAVGWGWLRKVPESRKELRGRTIPIRIAGVDAPEGAHFGKPAQPFAAEALDWLTNYILNRNVRAYIYKRDQYERVVATVYVRRFLFRKDVGLEMIKRGLATTYEAKSGAEFGGMKEVYEKAQAKAKRKRKGMWSGKASEFESPREYKTKWAAHDKSNSS
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: CAIT_SALCH
Sequence: MKNEKKKSGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDEKPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKEIGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMDVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMHLPRMLFYTDAIGKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLMDKNILNIPQLIEQHGVARAIIETWAALPLSTATMWGFFILCFIATVTLINACSYTLAMSTCREVRDGEEPPLLVRIGWSVLVGIIGIVLLALGGLKPIQTAIIAGGCPLFFINIMVTLSFIKDAKVHWKDK
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NS1_INBAD
Sequence: MADNMTTTQIEVGPGATNATINFEAGILECYERLSSQRALDYPGQDRLNRLKRKLESRIKTHNKSEPESKRMSLEERKAIGVKMMKVLLFMNPSAGIEGFEPYCMKNSSNSNCPNCNWTDYPPTPGKCLDDIEEEPENVDDPTEIVLRDMNNKDARQKIKEEVNTQKEGKFRLTIKRDIRNVLSLRVLVNGTFLKHPNGYKSLSTLHRLNAYDQSGRLVAKLVATDDLTVEDEEDGHRILNSLFERFNEGHSKPIRAAETAVGVLSQFGQEHRLSPEEGDN
What is the function of this protein?
Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins.  Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response.  Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR.  Also binds poly(A) and U6 snRNA.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza B viruses NS1 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: GLGB_BORPE
Sequence: MMRDSPSIQGTLDAATQHALLAGRHADPFSVLGPHQAGAHTVVRVLAPGARTVMAVLPGGQRTPLLPMQPGLFENTVPGLQPGAPAAYRLCIEWEGGIQHTADPYAFGPVLDAAQLDHCAAGGWRYLAGLLGAHAASVDGCAGTRFALWAPNARRVAVVGDFNGWDGRRHAMRLRYPAGVWELFLPDVGPGARYKFQVLGADGHTVLKADPLARQAEAPPATASIVPDERPFAWTDKAWMEQRAARQRCDAPISIYEVHAGSWFDDAGAPRWQNLAARLPEYARSLGFTHIELLPVMAHPFGGSWGYQPLGLFAPAAAHGAPADFAHFVDRCHEAGLGVILDWVPAHFPDDAHGLARLDGTPLYEHADPREGRHPDWNTLIYNYGRREVRTFLIASAIHWLRHYHVDGLRVDAVASMLYRDYSRPAGQWIPNRHGRRENLEAIDFLRELNAAVGVQCPGAITVAEESTAWPGVTAPVANGGLGFDYKWNMGWMHDTLRYMRRDPIHRRHHHHDLSFGMVYAYAERFVLPLSHDEVVHGKGSLLGKMPGERAAQLAQLRLYYAFMWAHPGKKLLFMGGEFGQQGEWNHDAMLQWSLLDDPAHRGLQRLVADLNHVYATLPELHCRDADPSGFAWIVGDDADNSVLAFARVDASHCLVAVCNFTPVPRPGYRFGVPHAGDWRVRVDTGATRYGGAGGGPPICLRSEPIPAHGHPQSLVLDLPGFTALYLRHSE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: IF5A2_CAEEL
Sequence: MSDDHHDDEHFHTGDSGAAATFPKQCSALRKNEHVMIKGRPCKIVEMSTSKTGKHGHAKVHMVAIDIFTSKKLEDICPSTHNMDVPVVKRREYLLMAIDDGYCSLMDPESCEQKDDLKLPDTELGQQIRDAYEKDEGSVLVQVVSAIGEEAILGWKVSTKE
What is the function of this protein?
mRNA-binding protein involved in translation elongation.  Has an important function at the level of mRNA turnover, probably acting downstream of decapping.  Critical for the efficient synthesis of peptide bonds between consecutive proline residues.  Can resolve ribosomal stalling caused by consecutive prolines during translation (By similarity).  Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.  Functions as a regulator of apoptosis (By similarity).  Acts in somatic tissues and its function in the soma is essential for normal growth and reproduction.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-2, eIF-5A-2, Initiation factor five protein 2.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y199_SYNY3
Sequence: MGSHCPLVSPSVGMISAGRQDYQKFFMCRLLGYLGQPLRPEQLIYRPEHSLIVQSYQPQEMTAGLLNADGFGLGWFDQESLPNPYLYKNVLPIWSDINLPHLSRYIQSSCFVSYVRSATPPLAVDLTNCQPFTEEGLLFVHNGFINNFRTTLYRPLRNLLSDASYQFIHGTTDSEHIFALILDNLRRLRQTSPGDSDWAKTSLGKALEASLLTLVELARQHDTFFSANILLADGQRIVACRYASRQPEPSLYWLANSERCPGGVIVASEPLFADQKWQACPSQSILVINSPEAIAVKVLANSVA
What are the official names of this protein?
Putative glutamine amidotransferase slr0199.
Protein: RPC1_BP434
Sequence: MSISSRVKSKRIQLGLNQAELAQKVGTTQQSIEQLENGKTKRPRFLPELASALGVSVDWLLNGTSDSNVRFVGHVEPKGKYPLISMVRAGSWCEA
What is the function of this protein?
Binds to two sets of three contiguous operator sites in the phage genome.
What are the official names of this protein?
Repressor protein CI.
Protein: GLRX2_CAMPM
Sequence: MKNVLIIFGKPYCSICENVSEAVEELKSEYDILHVDILSFFLKDGDSSMLGDVKRGTLIGNFAAHLSNYIVSIFKYNPQTKQMAFVDINKSLDFTKTDKSLVNLEILKSEIEKANYGVWPPVTE
What is the function of this protein?
Glutaredoxin necessary for virion morphogenesis and virus replication.  Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053.  The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088.  Exhibit thioltransferase and dehydroascorbate reductase activities in vitro.
What are the official names of this protein?
Glutaredoxin-2.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RUTD_SHIFL
Sequence: MKLSLSSPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTMLVSVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: NAGK_SALG2
Sequence: MYYGFDIGGTKIALGVFDSTRRLQWEKRVPTPHTSYSAFLDAVCELVAEADQRLGVKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLVLNGKPITGQSYITGEFGHMRLPVDALTLMGFDFPLRRCGCGQMGCIENYLSGRGFAWLYQHYYDQSLQAPEIIALWEQGDEQAHAHVERYLDLLAVCLGNILTIVDPDLLVIGGGLSNFTAITTQLAERLPRHLLPVARAPRIERARHGDAGGMRGAAFLHLTD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: SCX7_CENLI
Sequence: MNSLLMITACLVLFGTVWAKEGYLVNTYTGCKYICWKLGENKYCIDECKEIGAGYGYCYGFGCYCEGFPENKPTWPLPNKTCGRK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Cll7.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OPGH_SHEON
Sequence: MTVSESSVLDTEVLVGGSAMPNERPGPMEPQSLSQMPEGFPRRSTVANGVRSRASRRFFVVGGALLLSSFAIYEMGAVFSIGGITPLEYLMLALFAINFCWIALAFCSGIAGFLLLLKKPKPNELAQTELHTRTAILMPTYNESPDRVFSAVSVMAEALSQTGHGHAFDWFILSDTTDPEIALLEEQAFLVLRQETHKHSRVYYRRRRKNVARKAGNVADFCRRWGSRYDHLLVLDADSLMESSTITGLAQRMQADPDAGLIQTIPSLINGTTLMARLQQFAARIYGPVIGTGLGWWVQKEGNFWGHNAIIRTEAFMGAAGLPNLKGKPPFGGHILSHDFVEAALIRRAGWSVVIAYDLPGSYEECPPSIVDLAVRDRRWCQGNLQHSRILPTKGLHWVSRLHLMTGIMAYLSSPFWLLLILTGLMLALQAHFIRPEYFTDQFSLFPTWPIMDSDRALRLFYITMVVLFGPKIFGVLLLLKDGKFARSVGGRIKAMFSVLFEVILSALIAPIMMFIHCGAVMSILMGRDSGWSPQRRDDGSMPWLTLIYRHRWHMLAGVMLGYAAILDSLTLLAWMSPALIGLWLAVPISAWTGSIKIGEFFKRIGILATPEERNPAPICIRAQEARAAYQSHIEQPWTLAQLLKDPALMELHLAMVDKQPLRAAGTPIEPVEAIVHVKVHEAQCQQSALALFNRQEMALVLANPLMLRSLQKLPEQFVPEDLVSFC
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNY_EXIS2
Sequence: MGTTTWIVILLLAILIAFIVGYFLRKSIAEAKIQGAETEATKIVERAQVSAEATKKEALLEAKDEAFKLRNEVEKELRERRQELTKQEGRLLQKEETLDRRVDSIDRKEEQINTRDAEIAKRKHQAEELERKVEDLYEQGRQELVRVANLSQDEARAIIMDETKQAAMHDAAILQKEIEQKAKEEADKKARNILSLAIQRFAAEHIAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREVAKMALEKLVQDGRIHPARIEEMVDKSRREVDERIREIGEEATYDVGIHGIHPDLVKILGRLKYRTSYGQNVLFHSLEVAHLAGMMAAELGEDVTLAKRAGLLHDIGKAIDHEVEGSHVEIGVELGTKYKEHPTVINAIASHHGDTEATSVISVLVAAADALSAARPGARQETLESYIRRLERLEEISESFDGVEKSFAIQAGREVRIIVRPDVVDDVLAHKMASDIRKKIEEELDYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NCPP_ERWT9
Sequence: MYHVVAATINPAKIKAISQAFSDIFGAGSCHIEGVEVDSGVAAQPISNTETRTGARQRVMNARRVRPEADFWVAIEAGIEEDTAFAWMVVENQKLRGESRSASFTLPAIVMKGIHQGRELGDEMARLTGIDNIKHKGGAIGAFTAGHLTRSSVYHQALILALCPFHNDIYQRKADDEDSDLI
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: 2ABB_CARAU
Sequence: MDEEIDTRKINNSFLRDHNYATEADIISTVEFNPTGELLATGDKGGRVVVFQREQESKSQPHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPRQNAAYFPLSTNDKTVKLWKISERDKRPEGYNLKDEEGRIRDPTTITTLRVPVLRPMDLMVEATPRRIFSNAHTYHINSISVNSDYETYMSTDDLRINLWNLEITNRSFNIVDIKPANMEELTEVITAAEFHPNQCNTFVYSSSKGSIRLCDMRTSALCDNHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYLMTRDYLTVKVWDINMESKPLETYQVHDYLRSKLCSLYENDCIFDKFECVWNGTDSVLMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCIGGKRRKDEISVDSLDFSKKILHTAWHPNENIIAVAATNNLYIFQDKVN
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, PP2A subunit B isoform B55-beta, PP2A subunit B isoform PR55-beta, PP2A subunit B isoform R2-beta, PP2A subunit B isoform beta.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Membrane.
Protein: Y160_HELP2
Sequence: MGRAFEYRRAAKEKRWDKMSKVFPKLAKAITLAAKDGGSEPDTNAKLRTAILNAKAQNMPKDNIDAAIKRASSKEGNLSEITYEGKANFGVLIIMECMTDNPTRTIANLKSYFNKTQGASIVPNGSLEFMFNRKSVFECSKSEVKNLKLSLEDLEFALIDYGLEELEEVGDRIIIRGDYNSFKLLNEGFESLKLPILKAGLQRIATTPIELNDEQMELTEKLLDRIEDDDDVVALYTNIE
What are the official names of this protein?
Probable transcriptional regulatory protein HPP12_0160.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_STRT2
Sequence: MAEKTYVMTLAEKKQLEAELEEYKLVRRPEVVERIKIARSYGDLSENSEYEAAKDEQAFIEGQIQILETKIRYAEIVDSDAVANDEVAIGKTVVVQEVGTSDKDTYHIVGAAGADIFSGKISNESPIAQALIGKKVGDKVAIESPAGSYSVEILSVEKTS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: GLO2_ALISL
Sequence: MLLIKSIPAFNDNYIWLIHNNDNHCVVVDPGEAAPVLACLKEHGLILDAILITHHHHDHIGGVPELVRQFPNINVVGPENEPIPTLTHPVGDGDFVELFNEKFMVLGVEGHTKGHIAYIGDEKLFCGDTLFSAGCGRLFEGTAEQMFHSLQKLAALPDETEVYCAHEYTASNLAFALAVEPDNDYLQQYREKVLRLRANGKATIPTTMQREKLINPFLRTSEASVKQAVSSKVENDSEVATFAALRRWKDEF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CLCL_RALSO
Sequence: MLAIAGLIGCAGALATIAFRECLRQLQWWLAGADQGLVATARALPWWARLLVPTAGGLLAGLTLQYGLKWIPRKGAEDYMEAIAVGDGVLSARQSLVRSASSLCSVASGASIGREGPMVQLAAMCGSLLGRVLRHAMPVSVEHMRLLVACGAAAGITSAYNAPIAGAVFVCEIVFGAITTATLGPLLVSAVTADIIVRQFFGYGAVYAMPHFDFVSGWEVLTYLGLGLAAGMAGPLLLGLIDRARGAFARTRLPQALRLALGGLIVGALSIRVPEVWGNGYSVVNGFLHAPWLWQTVALVLVCKVGATAASAGSGAVGGVFTPTLFCGAALGLLYGTGMHALLPGAAPVPVSYAVVGMGALLAATTHAPLMSILMIFEMTLSYQVVLPLMLACITGYVTAHATGAPSVYARALARNRDDTLRLPPASSP
What are the official names of this protein?
Putative chloride channel protein ClcB-like.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UCRI_SYNJA
Sequence: MTEAVSNFEAPPMSRRVFLNALLSSSVGVVVVGTLYPVVKYFIPPSSGGAGEGVIAQDALGKPISVSELLATHAATDRVLAQGLKGDPTYIVIDNGAVANYGLNAVCTHLGCVVPWNAGENLFKCPCHGSQYAANGKVIRGPAPRSLELVSATVDGDNVRFSPWQGPDFREA
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: BXA8_BOMMO
Sequence: MKLLLTIALMLSTVMWVSTQQPQEVHTYCGRHLARTMADLCWEAGVDKRSDAQFASYGSAWLMPYSAGRGIVDECCLRPCSVDVLLSYC
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin A-8, BBX-A8, 4K-prothoracicotropic hormone, 4K-PTTH.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLPK_AQUAE
Sequence: MSVVISIDVGTTRVKVIAFSKNGKIVAISDREVSQIYPEPGWVEQDPLELWEAVRKSLSEVIQQVGLKEINSIGITNQRETVILWDKETGRPVYNAILWQDLRTEDICRKLSEYSEYIKENTGLLLHPYFSASKVNWIIENVNGVKKDIERGKVIFGTVDTWILWNLTGGKVHKTEPSNASRTLLFNIKRLEYDDELLKIFRIPKNILPEVNESSSLFGYTDKSITGVEIPITGILGDQQASLFAHGIRELEEVKNTYGTGLFLMLLTGSKPIIPERLLGTVAWVINGKVNYAIEGSVLTGGACIKWLMDRLKLIKQAADTEYLAKSISSNEGVYFVPAFSGLGAPYWDASARGIIIGITGRTRIEHIARAALEAIAYQTRDVIEEMEKETGVKIKILKADGGASQNNFLMQFQADILGIPVERPRHVELTALGAAGIAGIYSGMWKSKEEFIEDTREVELTFSPEMKKEERELYYSKWKDAVKRAMKWSML
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: FMO2_RABIT
Sequence: MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDGRASIYQSVITNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDFASSGQWEVVTQSNSKQQSAVFDAVMVCSGHHILPNIPLKSFPGIEKFKGQYFHSRQYKHPAGLEGKRILVIGIGNSASDIAVELSKKAAQVYISTRKGSWVMSRISEDGYPWDMVFHTRFSSMLRNVLPRMIVKWMMEQQMNRWFNHENYGLAPENKYLMKEPVLNDDLPSRILYGTIKVKRRVKELTESAAIFEDGTVEEDIDVIVFATGYTFAFPFLEESLVKIEDNMVSLYKYMFPPQLEKSTFACLGLIQPLGSIFPTVELQARWATRVFKGLCSLPSKETMMADIIKRNENRIALFGESLSQKLQTNYIDYLDELALEIGAKPDLVSFLFKDPKLAVKLYFGPCNSYQYRLVGPGQWEGARNAIFTQKQRILKPLKTRTLKASSNFPVSFLLKFLGLFALVLAFLFQLQWF
What is the function of this protein?
Catalyzes the oxidative metabolism of numerous xenobiotics, including mainly therapeutic drugs and insecticides that contain a soft nucleophile, most commonly nitrogen and sulfur and participates to their bioactivation (PubMed:3785145, PubMed:10950853, PubMed:16620765, PubMed:11302936, PubMed:15144220, PubMed:15294458).  Most drug substrates are tertiary amines such as prochlorperazine and trifluoperazine which are N-oxygenated to form the N-oxide, or sulfides such as thiourea and ethionamide, which are S-oxygenated to the sulfoxide (PubMed:3785145, PubMed:15144220, PubMed:16620765).  Others include primary alkylamines such as N-dodecylamine and octan-1-amine that are sequentially monooxygenated to oximes through intermediate hydroxylamines and both steps are NADPH- and oxygen-dependent (PubMed:3785145).  Also metabolized N-Deacetyl ketoconazole (DAK) to N-hydroxy-DAK and appears to further metabolizes N-hydroxy-DAK to two others metabolites (PubMed:10950853).  Also catalyzes S-oxygenation of the thioether-containing organophosphate insecticides, phorate and disulfoton (PubMed:15294458).
What are the official names of this protein?
Dimethylaniline monooxygenase [N-oxide-forming] 2, Dimethylaniline oxidase 2, FMO 1B1, Pulmonary flavin-containing monooxygenase 2, FMO 2.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CLP1_DROPS
Sequence: MSDHQNRGQDFSLEADSELRFEIEQKDAKVLVTLVNGFAELFGTELVKKKKYEFGMGAKVAIFTYQGCVLHVTGKMDVCYISKETPMVQYVNCHAALEQFRTEAEEKDRRGPVAMVVGPTDVGKSTLCRILLNYAVRVGRRPLYADLDVGQGAIAISGNVATILIERPASVEEGFPKTAPLVYHFGHKSPSGNSVLYNAVVSKMAEVTLQSLNGNKRTKSSGIIVNTCGWVKGHGYAHLLHAARAYGACAIFVLDQERLYNELLRDVPSSVHVVLLPKSGGVVERSKELRHECRDQRIKEYFYGNARAPFYPFSFEVKFQELRLYKIGAPPLPDSCMPIGMKAEDNKTKVVAVTPTPALIHHVLALSFAESVDDDVIGTNIAGFCCVTEVDMERQVVMLLSPQPRPLPPNALLLWSELQFMDNHT
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
Protein CLP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDH_PROMH
Sequence: MKVAVLGAAGGIGQALALLLKNQLPAGSELSLYDIAPVTPGVAADLSHIPTQVRVKGFAGEDPSPALKDADVVLISAGVARKPGMDRSDLFNVNAGIVRNLIEKVAQNCPKALIGIITNPVNTTVAIAAEVLKKAGVYDKKRLFGVTTLDIIRANTFVAELKGKDPQTTNVPVIGGHSGVTILPLLSQVAGVSFTDEEVAALTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLIRALNGEKDVIECTYTEGDGEHARFFAQPVRLGKNGVEEYLPIGQLSDFEKQSLNGMLDVLKKDIILGEEFINK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: PXPA_BACMK
Sequence: MTTIDLNCDLGESFGAYKMGNDDEILPFVSSINVACGFHAGDPAVMRQTVEKALQHNVAIGAHPGFPDLIGFGRRNMSVSASEVYDYVLYQIGALDGFVKAAGGKMQHVKPHGALYNMAVTDSEIADAIAKAIYHINPGLLLYGLANSEAFIKATEKYNITLVQEAFADRTYKQDGTLTSRTEENALIKNEDEAIKQVLQMVKEGYVESVNGGKVAVQAQTICLHGDGEKAVQFAEKIYRTFKLNGISICAPNK
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: PTH_CLOB1
Sequence: MYLVVGLGNIGKEYKKTRHNIGFDVVDIIAEKYNIEINRQKFKGSYGEGRIGNEKIILLKPSTYMNLSGESVIEAANFYKIDKENIIVIYDDMSIDIGKLRVRSKGSAGGHNGIKNIIQHLNSDIFPRVRVGIGQPDENVVNYVLGKFSKDEREIIEKVLAMSAKACISIVEDGVTEAMNKYNGVKIEV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCML_AFIC5
Sequence: MNIQTTVEPTSAERAEKLQGMGCKRKRVEDIRFTQGKGNYVDDVKLPGMLFGDFVRSSHAHARIKSIDTSKAKALPGVFAVLTAADLKPLNLHYMPTLAGDVQAVLADEKVLFQNQEVAFVVAKDRYVAADAIELVEVDYEPLPVLVDPFKAMEPDAPLLREDIKDKMTGAHGARKHHNHIFRWEIGDKEGTDATFAKAEVVSKDMFTYHRVHPSPLETCQCVASMDKIKGELTLWGTFQAPHVIRTVVSLISGLPEHKIHVIAPDIGGGFGNKVGAYSGYVCAVVASIVLGVPVKWVEDRMENLSTTSFARDYHMTTELAATKDGKILAMRCHVLADHGAFDACADPSKWPAGFMNICTGSYDMPVAHLAVDGVYTNKASGGVAYRCSFRVTEAVYAIERAIETLAQRLEMDSADLRIKNFIQPEQFPYMAPLGWEYDSGNYPLAMKKAMDTVGYHQLRAEQKAKQEAFKRGETREIMGIGISFFTEIVGAGPSKNCDILGVSMFDSAEIRIHPTGSVIARMGTKSQGQGHETTYAQIIATELGIPADDIMIEEGNTDTAPYGLGTYGSRSTPTAGAATAVAARKIKAKAQMIAAHMLEVHEGDLEWDVDRFRVKGLPEKFKTMKELAWASYNSPPPNLEPGLEAVNYYDPPNMTYPFGAYFCIMDIDVDTGVAKTRRFYALDDCGTRINPMIIEGQVHGGLTEAFAVAMGQEIRYDEQGNVLGASFMDFFLPTAVETPKWETDYTVTPSPHHPIGAKGVGESPHVGGVPCFSNAVNDAYAFLNAGHIQMPHDAWRLWKVGEQLGLHV
What is the function of this protein?
Catalyzes the oxidation of carbon monoxide to carbon dioxide.
What are the official names of this protein?
Carbon monoxide dehydrogenase large chain, CO dehydrogenase subunit L, CO-DH L.