PharMolix/UniProtQA huggingface dataset:
Protein: RL17_FRATT
Sequence: MRHRKQGRKFGRTSSHRKAMFKNMSASLINHELIKTTLPKAKELRAIVEPLVTLAKREHKLRQELDTNSNEFKAQSVALRRQAFDFLRNKAAVTKLFEEFGARYAERAGGYTRILKCGYRFGDKAPMAFIELVDRPQVEEAADEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TMM98_BOVIN
Sequence: METVVIVAIGVLATIFLASFAALVVVCRQRYCRPRDLLQCYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASLSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLTAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI
What is the function of this protein?
Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination.  Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation.  The secreted form promotes differentiation of T helper 1 cells (Th1).
What are the official names of this protein?
Transmembrane protein 98.
What is the protein family that this protein belongs to?
Belongs to the TMEM98 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Secreted. Secreted, extracellular exosome. Note=Secreted by exosomes through a non-classical pathway.
Protein: CKS1_DROME
Sequence: MSKDIYYSDKYYDEQFEYRHVVLPKELVKMVPKTHLMTEAEWRSIGVQQSRGWIHYMIHKPEPHILLFRRPKTD
What is the function of this protein?
Binds to the catalytic subunit of the cyclin dependent kinases Cdk1 and Cdk2, and is essential for their biological function.
What are the official names of this protein?
Cyclin-dependent kinases regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the CKS family.
Protein: NU6M_DICCI
Sequence: MSTLGLLLILLGIIITCTFVILRSVNPIYSILNLIVIYGCYASILLTVEMEFLACIYILVNVGAIAVLFLFIVMMININIVEIQETMKKYNIYMFVGFIGLIGIMGILITNYQIRIKEEVIADFSMFLLNTEITTLQATPSYLDFYELFVETTDLRAMGSNVIYGSQSIWFIMACIILLIGMVGVIYITEDLIIEKRKLNARRRQDINSQVLREYKITIKNYREIK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: IDI_PHOPR
Sequence: MIIEEQVVLVDQQGRALGLQEKMQAHRDGALHLAFSVLLYRETTQGIEFLMQQRALGKYHSGGLWTNTCCSHPRQGETLEQAGLRRLTEEMGIVGLESLDDIASFVYRAELDNQLIEHEWDHVLIANGTELAIIPNSEEVKSYRWWSKADLELGLADTPELFTAWFPQVLQYVINELSSQ
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRKS1_ARATH
Sequence: MSWQWRRRQWPSPLLLILIVLHLVSSSSAIDFLYNSFSSVTNRTDVILIEDSRVESTVISLINDSDPLSFGRVFYPQKLTIIPDPTRNPTRLSSFSTSFVFSILPDISTSPGFGLCFVLSNSTSPPNAISSQYFGLFTNATVRFNAPLLAVEFDTGRNSEVNDIDDNHVGIDLNNIESTTSVTAGYYDSVNGSFVRFNMRNGNNVRAWIDFDGPNFQINVSVAPVGVLRPRRPTLTFRDPVIANYVSADMYAGFSASKTNWNEARRILAWSLSDTGALREINTTNLPVFFLENSSSSLSTGAIAGIVIGCVVFVALIGFGGYLIWKKLMREEEEEEIEEWELEFWPHRFSYEELAAATEVFSNDRLLGSGGFGKVYRGILSNNSEIAVKCVNHDSKQGLREFMAEISSMGRLQHKNLVQMRGWCRRKNELMLVYDYMPNGSLNQWIFDNPKEPMPWRRRRQVINDVAEGLNYLHHGWDQVVIHRDIKSSNILLDSEMRGRLGDFGLAKLYEHGGAPNTTRVVGTLGYLAPELASASAPTEASDVYSFGVVVLEVVSGRRPIEYAEEEDMVLVDWVRDLYGGGRVVDAADERVRSECETMEEVELLLKLGLACCHPDPAKRPNMREIVSLLLGSPQEDLLTGLTPAAAAADSTAAHA
What is the function of this protein?
Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici and to the pathogenic bacteria Pseudomonas syringae.
What are the official names of this protein?
L-type lectin-domain containing receptor kinase S.1, LecRK-S.1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
Protein: MOAB_BACSU
Sequence: MSVQEHKQEAPDIVRCKVITVSDTRTDETDKSGKLMISFLEEAGHHIAAYEIVKDEKDALQRSVLAGCMDEQTDAVLLNGGTGIADRDVTIEAITPLFSKELPGFGEIFRMLSYTEDIGSAAIMSRATAGVIQHTAVFSTPGSSGAVKLAMNKLIIPELAHVVREIRKDK
What is the function of this protein?
May be involved in the biosynthesis of molybdopterin.
What are the official names of this protein?
Molybdenum cofactor biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the MoaB/Mog family.
Protein: TRM1_THEAC
Sequence: MIVREGSAEILVPEVYHGPGKRGTGFYNADQKINRDITIEFIKKMGIRNVLDGFGGTGIRGIRISKETDSAVTISEVSPDSYRLIRDNVERNGSQASVINDSFECVLQHGAYEYVDVDPYGSPVPYLDAALMGVKRNGFLGVTATDQSALTGSVPHKTRIRYDALIKNDTFRHEMGIRLLIGYMAKRAASLGRFIDPLISIWHGHYYRVFVRVRKGFEGAGRMMQNLGYVNKHNLLSGIYQDMDEGPVWKGNLQDNAVAEAVLASAGHKAFNPEENRLLFCDLTDIARARHTSLPDIESVIDALSSSGHAASRTMFSPTGIKTDASCDLVESLMMDTLHRRSPA
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: C2D61_ARATH
Sequence: MESSLIHHIIIVLLLLWFISSLNRSHAFFYFLALIYLYLVHERYVMRLKRKLQFEERKQANQRRVLSDSESVRWMNYAVEKIWPICMEQIASQKILGPIIPWFLEKYRPWTAKKAVIQHLYMGRNPPLLTDIRVLRQSTGDDHLVLELGMNFLAADDMSAILAVKLRKRLGFGMWTKLHLTGMHVEGKVLIGVKFLRRWPFLGRLRVCFAEPPYFQMTVKPIFTHGLDVAVLPGIAGWLDKLLSIAFEQTLVQPNMLVVDMEKFVSPTSENWFFVDEKEPVAHVLVEVFEASDLKPSDLNGLADPYVKGKLGAYRFKTKIQKKTLSPKWHEEFKIPIFTWDSPSILNIEVGDKDRFVDDTLGECSVNIEEFRGGQRNDMWLSLQNIKMGRLHLAITVIEDNAKSSDDPLKKAKLNKEDIQTSFASDTTNLGSFSSDKSPSVVDNFEPIKIDGQEETAIWVQKPGAEVSQIWEPRKGKSRRLDSQIQRTPNDESLSNGSSSTDDNQEGSKNPMKSVGRGLRKIGSMFHRNVKKEEFLIGSIEEESQSQSPRINLKAVNQKDVGLNFIVDDNLSGPLSGKSLDGESLDAEENSGKGHMKDVAKSFLKQAEKSAKQIKHAFSRKGSMKPRDGHKEIVPESDSGTDSESSDDDDAFTCVKNLATEPGKLTRDGNIERTGDDDHVDSTTLATAKEDSSGDILEDSTDVEAKEEKLKEAAESETRDMDTAMNIKTEDEKGDTLKNIEEGEEKESSSK
What are the official names of this protein?
C2 domain-containing protein At1g53590, N-terminal-TM-C2 domain type 6 protein 1, NTMC2TYPE6.1.
What is the protein family that this protein belongs to?
Belongs to the extended synaptotagmin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KR104_HUMAN
Sequence: MSVCSSDLSYSSRVCLPGSCDSCSDSWQVDDCPESCCEPPCCAPSCCAPAPCLSLVCTPVSRVSSPCCPVTCEPSPCQSGCTSSCTPSCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVCCVPVCCGDSSCCQQSSCQSACCTSSPCQQACCVPICCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCISSCTPSCCQQSSCQPACCTSSSCQQACCVPVCCKTVCCKPVCSEDSSSCCQQSSCQPACCTSSPCQQACCVPVCCKPVCCKPVGSVPICSGASSLCCQQSSCQPACCTSSQSQQGCCVPVCCKPVSCVPVCSGASSSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVCRPACCVPVPSCCAPTSSCQPSCCRPASCVSLL
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 10-4, High sulfur keratin-associated protein 10.4, Keratin-associated protein 10.4, Keratin-associated protein 18-4, Keratin-associated protein 18.4.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 10 family.
Protein: Y1323_SHEB2
Sequence: MKKQLLSALIGASLLAPMAASAADYVIDREGAHASITFKVSHLGYSYVVGRFNDFSGDFSYDAAKPTAAKVNVTVNTLSVDSNHAERDKHIRSADFLNTSKFAQATFTSTTVEDKGNGDLVINGNLTLNGVTKPLAINAHAVGEGQDPWGGYRAGFTGTTTFAMKDFGIKMDLGPASSHVELDLVVEGVRK
What are the official names of this protein?
UPF0312 protein Sbal223_1323.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: COAA_MYCLB
Sequence: MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPGRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMRFVTSVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFLAMRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANFB_BOVIN
Sequence: MDPQTALSRALLLLLFLHLSLLGCRSHPVGGPGPVSELPGLQELLDRLRDRVSELQAEQLRVEPLQQGQGLEETWDSPAAAPAGFLGPHHSILRALRGPKMMRDSGCFGRRLDRIGSLSGLGCNVLRRY
What is the function of this protein?
Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (By similarity).  May also function as a paracrine antifibrotic factor in the heart (By similarity).  Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses.  Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion.  Binds the clearance receptor NPR3 (By similarity).
What are the official names of this protein?
Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Aldosterone secretion inhibitory factor]: Secreted.
Protein: PYRH_CLOTE
Sequence: MNDIKYKRIMLKLSGEALAGENGYGLDFKVVKRISKEIKELVDMGVEIGAVVGGGNIWRGRNGEDMDRTTADYMGMLATCINAMALQDSLEQLGVDTRVQTAIEMKEVAEPFIRRRAMRHLEKGRVVIFAAGTGNPYFSTDTTAALRAAEIEADIILLAKKVDGVYDKDPHKHEKAQKFETLTYIDVLDQGLQVMDSTATSLCMDNNIPILVFALDAPGNIRKAISGEKIGTIVCKE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MHPB2_DECAR
Sequence: MAALLQCISHSPMKGYVDPSPAIVSDVEVAIARMRKELVDFDPEVIFLFAPDHYNGFFLDVMPQFCVGIAATSVGDYRTTPGPINVPREIARSCAEHLISNDIDVAISYRMQVDHGMVQPLEELMGGLNAYPVVPLFVNGVAPPLISIRRARLFGAAVGEYAKKLNKRCLFIGSGGLSHNPPVPQIDTATEEFAEFLIAGRNPSPERRAARQQRTKDAAIRFAAGDSQLHPINSVWDEAFMADLVNQDWGALDAYRNSEITEQAGISTHEAKSWVAAHAAMNAATSGGYMAEVRYYKAIPEWIVGYGAMAGSAEQAT
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase 2, 3-carboxyethylcatechol 2,3-dioxygenase 2.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: PME22_SOLLC
Sequence: MATPQQPLLTKTHKQNSIISFKILTFVVTLFVALFLVVFLVAPYQFEIKHSNLCKTAQDSQLCLSYVSDLMSNEIVTTDSDGLSILMKFLVNYVHQMNNAIPVVSKMKNQINDIRQEGALTDCLELLDQSVDLVSDSIAAIDKRTHSEHANAQSWLSGVLTNHVTCLDELDSFTKAMINGTNLDELISRAKVALAMLASVTTPNDDVLRPGLGKMPSWVSSRDRKLMESSGKDIGANAVVAKDGTGKYRTLAEAVAAAPDKSKTRYVIYVKRGIYKENVEVSSRKMKLMIVGDGMHATIITGNLNVVDGSTTFHSATLAAVGKGFILQDICIQNTAGPAKHQAVALRVGADKSVINRCRIDAYQDTLYAHSQRQFYRDSYVTGTIDFIFGNAAVVFQKCKLVARKPGKYQQNMVTAQGRTDPNQATGTSIQFCNIIASSDLEPVLKEFPTYLGRPWKKYSRTVVMESYLGGLINPAGWAEWDGDFALKTLYYGEFMNNGPGAGTSKRVKWPGYHCITDPAEAMPFTVAKLIQGGSWLRSTGVAYVDGLYD
What is the function of this protein?
Pectinesterase may play a role in cell wall metabolism during fruit growth and development prior to ripening and may be required for preparing cell walls for softening by polygalacturonase during fruit ripening.
What are the official names of this protein?
Pectinesterase 2.2, PE 2.2, Pectin methylesterase 2.2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: Y1754_YERPB
Sequence: MSVTDLVLVVFIALLLIYAIYDEFIMNMMKGKTRLQVHLKRKNKLDCMIFVGLIGILIYNNVMAHGAPLTTYLLVGLALVAVYISYIRWPKLLFKNTGFFYANTFIEYSRIKSMNLSEDGILVIDLEQRRLLIQVKKLDDLEKIYNFFIENQS
What are the official names of this protein?
UPF0266 membrane protein YPTS_1754.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIR1_HHV7J
Sequence: MDPNNKVSINKNMGLLRKCLCHDEYNKKRFCYSRFHHKTLLYKQLYEISKILRRLNSGLDMWCLRDAIISALGAMHDAPHVDRLLGQFYLKTNSASEFDSISLILESENILQKELIEFVRDSKVELEKILQAAIHVWRAKFSPGVLAASRFLDEISNSFNGIEENIPTIFLRISVTLASQIKKIEYLQKSFVSHKCPLVEEILILLYKRVCMLPFPCMSNLGLVSEKKSVFDTVFHNVSNFSLEDFLDINSGFFLPAMLNGSYVSVNLTRYHYEAESLMELLLSQLQIVEKDTNKTTGLTIYLEIWHLSLLMWLDFCEILPTTVQVKFCLILPEIFMERLKTENSYWSVFHKALAINLGLYDESDFTSKYLECERTAEHARIKTETLLDNICRCLRRGQMGFIFRKNIHKYSMLPQIASYCLGNSMDVIPFEYGLNTAFRIALNLSYFVENVSEEQKSHTNIDMFHYRDKIFNLKKMRKTVTELVLIGNAVIDYALENRDFLMDGIVNARSLAICVTGLHSALMSMNLPFNSQLGCQLYRIVCENIYYSSVRTSMNCCKKGAEPCSFFQRSKYAQGILHCDLYDNVEYTLPNVLWTNLRSDIKKYGLRNLTFVSGSAMSKEFDLLNCSQSFCPIEGNKILKRSSIKVLHPNPVFHSDLSVYSTELQTLYIPVYNGLFLNRFKNHLEYLSSVNYDVSKVNKNLFSEEEMQEMTIFLNAFDYSVNEMLNMYVGALPFTDHGQANVFFINKTENMRDILVCLYQNGFKTGIYQAVYKNQKCDGVNPSKKFDLLSGFSDGVVMSTMHVFQ
What is the function of this protein?
Does not possess a ribonucleotide reductase activity.  Betaherpesviruses probably use another strategy to expand the dNTP pool in a quiescent host cell.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit-like protein.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: S2538_YEAS7
Sequence: MTEQATKPRNSSHLIGGFFGGLTSAVALQPLDLLKTRIQQDKKATLWKNLKEIDSPLQLWRGTLPSALRTSIGSALYLSCLNLMRSSLAKRRNAVPSLTNDSNIVYNKSSSLPRLTMYENLLTGAFARGLVGYITMPITVIKVRYESTLYNYSSLKEAITHIYTKEGLFGFFRGFGATCLRDAPYAGLYVLLYEKSKQLLPMVLPSRFIHYNPEGGFTTYTSTTVNTTSAVLSASLATTVTAPFDTIKTRMQLEPSKFTNSFNTFTSIVKNENVLKLFSGLSMRLARKALSAGIAWGIYEELVKRFM
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNH2_CAUVN
Sequence: MPPGPDMTLELACGQAPVCGVDEAGRGPWAGPVSAGAVILDPDRIPKGLNDSKKLSAKARAALEEEIKDVAISWCVGLASIEEIAQLNILHAAGLAMRRAVEGLAVTPAFALVDGNYAFKLPCPVKTVIKGDSLSCSIAAASILAKEARDRIMIEADALYPGYGFAGHKGYHAKVHVEGLRRLGPSPIHRLGWAPVKAALAAAAVNGELDL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_CERS4
Sequence: MPAIESGLWALILTGVLGYLLGSIPFGIVITRALGLGDLRKIGSGNIGATNVLRTGNKPAALATLLLDSGKGAIAVLIARAAVGEDAAQLAAFTSFLGHLFPVWLGFRGGKGVATFLGTLLALAWPVGLACCLTWLATAALGRISSLSALVAAASGVLWMILLGYGQMAALGAVLAVLIFIRHHANIRRILAGTEPRIGKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRL_TRIVU
Sequence: MGTKRSSLKGSLLLLLLMSSLFLFKSVESLPICPSGAVNCQVSLSDLFDRAVMLSHYIHSPSSEMFNEFDERYAQGRGFITKAINSCHTSSLSTPEDKEQAQQIHHEDLLNLILRVLRSWNDPLYHLVTEVRSMQEAPDTILSKAMEIEEQNKRLLEGMEKIVGQVHPGDRENEVYSVWSGLPSLQMADEDTRLFAFYNLLHCLRRDSHKIDNYLKLLKCRLIHDSNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation, mammogenesis, mitogenesis and osmoregulation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRE1_NEUCR
Sequence: MQRVQSAVDFSNLLNPSESTAEKRDHSGSPRQQTAQPQQQQQQPQPEADMATVGLLRPNGPLPGAQATEPANELPRPYKCPLCDKAFHRLEHQTRHIRTHTGEKPHACQFPGCSKKFSRSDELTRHSRIHSNPNSRRGNKGQQQQQHPLVHNHGLQPDMMPPPGPKAIRSAPPTAMSSPNVSPPHSYSPYNFAPSGLNPYSHSRSSAGSQSGPDISLLARAAGQVERDGAAHHHFQPRFQFYGNTLHAATASRNQLPGLQAYHMSRSHSHEDHDDHYGQSYRHAKRSRPNSPNSTAPSSPTFSHDSLSPTPDHTPLATPAHSPRLRPHPGLELPPFRNLSLGQQHTTPALAPLEPALDGQFSLPQTPPAAPRSSGMSLTDIISRPDGTQRKLPVPKVAVQDLLGPADGFNPSVRNSSSTSLSGAEMMDRL
What is the function of this protein?
Involved in carbon catabolite repression.  Represses the transcription of a number of genes by binding to a GC-rich region in their promoter (By similarity).
What are the official names of this protein?
DNA-binding protein cre-1, Carbon catabolite repressor.
What is the protein family that this protein belongs to?
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIRB4_HUMAN
Sequence: MIPTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVPHSGLRRHWEVLIGVLVVSILLLSLLLFLLLQHWRQGKHRTLAQRQADFQRPPGAAEPEPKDGGLQRRSSPAADVQGENFCAAVKNTQPEDGVEMDTRQSPHDEDPQAVTYAKVKHSRPRREMASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSFTLRQKATEPPPSQEGASPAEPSVYATLAIH
What is the function of this protein?
Inhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance (PubMed:11875462).  Receptor for FN1 (PubMed:34089617).  Receptor for apolipoprotein APOE (PubMed:30333625).  Receptor for ALCAM/CD166 (PubMed:29263213).  Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (PubMed:9151699).  Inhibits FCGR1A/CD64-mediated monocyte activation by inducing phosphatase-mediated down-regulation of the phosphorylation of multiple proteins including LCK, SYK, LAT and ERK, leading to a reduction in TNF production (PubMed:19833736).  This inhibition of monocyte activation occurs at least in part via binding to FN1 (PubMed:34089617).  Inhibits T cell proliferation, inducing anergy, suppressing the differentiation of IFNG-producing CD8+ cytoxic T cells and enhancing the generation of CD8+ T suppressor cells (PubMed:16493035, PubMed:19833736, PubMed:29263213).  Induces up-regulation of CD86 on dendritic cells (PubMed:19860908).  Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation (PubMed:11875462).
What are the official names of this protein?
Leukocyte immunoglobulin-like receptor subfamily B member 4, B4, CD85 antigen-like family member K, Immunoglobulin-like transcript 3, ILT-3, Leukocyte immunoglobulin-like receptor 5, LIR-5, Monocyte inhibitory receptor HM18.
Protein: MATK_AVIGE
Sequence: MEEIKRYLQRNRSHHQDFLYPLIFQEYIYAFAHYRGFSQSILSENPGYDNKSSLLLVKRLITRMYQQNHFLIFPNDSNQNPFFARNKNLYSQIIPEGFAFIVEIPFSLRLISCLEGKKIVKSQNLRSIHSIFPFLENNFSHFHFVLDVLIPHPVHVEILVQTLRYWLKDASSLHLLRFFLNEYCNWNSCILPKKAGSSFSKRTQRLFLFVYNSHVWEYESIFVFLRNQSAHLRSISSGVLLERIYFYGKMERLVNVFVKVKDFRSNPGLIKEPCMHYIRYQRKSILASKGTSLFMNKWKCYLVTLWQWHFSLWFHPRRIYINQLANHSLEFLGYLSSVRMNPSVIRSQILENAFLINNAIKKFDTLVPIIPLIMSLAKAQFCTVLGHPISKPVWADLSDSNIIDRFRRISRNLSHYHSGSSTKKSLYRIKYILRLSCVRTLARKHKRTVCVFLKRSGSELLEEFLMSEEGVPFFTFQKGFSTLRGIYRSRVWYLDIFSINDLANHK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PEPB_SALAR
Sequence: MTEAMNITLSTQPADARWGDKATYSINNDGITLHLNGNDDLGLIQRAARKIDGLGIKQVALTGEGWDIERCWAFWAGYKGPKGVRTVMWPDLDDAQRQELDNRLTIIDWVRDTINAPAEELGPEQLAQRAVDLLCSVACDHVTYRITKGEDLREQNYMGLHTVGRGSERSPVLLALDYNPTGDKDAPVYACLVGKGITFDSGGYSIKQSAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIIRYRNGKNVEVMNTDAEGRLVLADGLIDASAQHPQLIIDMATLTGAAKTALGNDYHALFSFDDTLAGRLLSSAAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYREGWLHIDCSATYRKAPVEQWAAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACO1_AJECA
Sequence: MALNEAPTASPVAETAAGGKDVVTDAARRPNSEPKKVHITDTPITLANWHKHISWLNVTLIIAIPIYGLVQAYWVPLHLKTALWAVVYYFMTGLGITAGYHRLWAHCSYSATLPLKIYLAAVGGGAVEGSIRWWARGHRAHHRYTDTDKDPYSVRKGLLYSHIGWMVMKQNPKRIGRTEITDLNEDPVVVWQHRNYLKVVIFMGIVFPMLVSGLGWGDWFGGFIYAGILRIFFVQQATFCVNSLAHWLGDQPFDDRNSPRDHIVTALVTLGEGYHNFHHEFPSDYRNAIEWHQYDPTKWTIWIWKQLGLAYDLKQFRANEIEKGRVQQLQKKIDQRRAKLDWGIPLEQLPVIEWDDYVDQAKNGRGLIAIAGVVHDVTDFIKDHPGGKAMINSGIGKDATAMFNGGVYNHSNAAHNQLSTMRVGVIRGGCEVEIWKRAQKENKEVESVRDEYGNRIVRAGAQVTKIPEPITTADAA
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Has high specificity and catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.  Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides.
What are the official names of this protein?
Acyl-CoA desaturase, Delta(9)-desaturase, Delta-9 desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.