PharMolix/UniProtQA huggingface dataset:
Protein: Y1460_XYLFA
Sequence: MIPNPTRDAPNIPSFVAADVGGTHVRVSVVAAAPTCASPPQLLDVRTYRCADYPSLSTILNDFLGTRSAVRDCVIASAGFQRSDGTVITTNLPWPLSPHRLRADLDLAEVSLVNDFEALAYATEDMEAAQLLHLTGPAKAQDGPRLLLGPGTGLGAALWIPNNGRPIVLPTEAGQAALPSTTELEMQLVRHMLNNRTHVPIEHALSGPGILNVYRALCALQSVLPQHASPDAISHAAAAGTDMLSSQTLEVFCDFLGSIVGDLVMMYGAQGGVYLAGGILPQLREPLLRSHFVERFLNKGPMGEALQHVPVRLIEHGQLGIVGAARWYLNKKAT
What are the official names of this protein?
Glucokinase-like protein XF_1460.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
Protein: CACB1_MOUSE
Sequence: MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPLGRAGTLRALSRQDTFDADTPGSRNSAYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEDEEDYEEEMTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGQGVYTR
What is the function of this protein?
Regulatory subunit of L-type calcium channels.  Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity).  Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane.  Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit.  Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit (By similarity).
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit beta-1, CAB1, Calcium channel voltage-dependent subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel beta subunit family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein.
Protein: KINUA_ORYSJ
Sequence: MAANGRASVRPVERHGAPPRPAGRSRSVAPPSRRPSPSPSRARPAAADNDGGSDSCRVRVAVRLRPKNSEDLAHGADFDSCVELQPECKKLKLKKNNWSCESYRFDEVFSENASQKRVYEVVAKPVVESVLEGYNGTVMAYGQTGTGKTYTVGRLGNDDPSEGGIMVRALEHILSVMSLETDSVAISFLQLYLESVQDLLAPEKTNIPIVEDPKTGEVSLPGAAKVEIRDLEHVFQLLQIGEMNRHAANTKMNTESSRSHAILIIHIQRSSRIEDGSNTSLPNGTDNLFPDNLPLVLKSKLLIVDLAGSERIDKSGSEGHMIEEAKFINLSLTSLGKCINALAENSPHIPTRDSKLTRILRDSFGGTARTSLIVTIGPSSRHFSETSSTIMFGQRAMKIVNTIRIKEEVDYESLYKKVEHEVDHLTSEMERQQKLKNSEKMQLEKKLKESEASLNDLKVTSNMQIENMAMEKRQLESTIKRLMLDLEKEKGKNNILSEQIIHLETSLDENKQKQLENISNTNILADTTKSHEKKIRELLKQLEDERSRSASMNDHLNVLQQQLSDAQNYFQKNIACELEKQLSRTTEEFASQISSLEERIADLISEKELVYEELKSTQEKMQQEMRHRQGLEDEILRLKQSLADNCSEESKALCGMVRSGSGLGSVPFMSKSGKSRELLSSQRSNISKIFEEVGLPNVLALLKSDELEVQIHAVKVVANLAAEDVNQEKIVEEGGLDALLSLLETSENTTIHRVTAGAIANLAMNGSNQGLIMNKGGARLLANIASKTNDPQTLRMVAGALANLCGNEKLHVMLKQDGGIKALLGMFRTGHNEVIAQIARGMANFAKCESRVISQGHRKGRSLLIEEGVLNWMVANSSAFSASTRRHIELAFCHLAQNEDNARDIILTGGIKELLRISRESSRDDTRNLAKKALNSNPAFFKEIQ
What are the official names of this protein?
Kinesin-like protein KIN-UA, Protein ARMADILLO REPEAT KINESIN1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Ungrouped subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: BETA_YERPE
Sequence: MEYDYIIIGAGSAGNVLAARLTEDADVTVLLLEAGGPDYRLDFRTQMPAALAFPLQGKRYNWAYETDPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNAMDFDHWASLSGLEDWSYLDCLPYFRKAETRDIGPNDFHGGEGPVSVTTPKIGNNPLFHAMVAAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPKGRRASTARGYLDQARPRNNLTIITHALTDRILFEGKRATGVRYLKGDAGTGQTAYARREVLLCGGAIASPQILQRSGIGPAELLQRLDIPLVQALPGVGENLQDHLEMYLQYSCKQPVSLYPALLWFNQPKIGIEWLFNGTGVGASNQFEAGGFIRSRDAFTWPNIQYHFLPVAINYNGSNAVKEHGFQAHVGSMRSPSRGRIQVKSKDPRQHPSILFNYMSSEQDWHEFRDAIRITREIIAQPALDPYRGREISPGANVQNDDELDAFIREHAETAYHPSCSCKMGDDKMAVVDGQGRVHGVQGLRVVDASIMPQIITGNLNATTIMIAEKIADRIRGCQPLAKSNAAYFIAGDTPARTSPVRHSLPVTSYP
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: YAB5_ORYSJ
Sequence: MMSSAPETFSLDHLSQHQQQQPPPLAEQEQLCYVHCNFCDTILAVGVPCSSLFKTVTVRCGHCANLLSVNLRGLLLPAAASTANQLPFGQALLSPTSPHGLLDEVPSFQAPASLMTEQASPNVSSITSSNSSCANNAPATSMASAANKATQREPQQPKNAPSANRTSEKRQRVPSAYNRFIKDEIQRIKASNPDITHREAFSAAAKNWAHFPHIHFGLMPDQGLKKTGIQSQDGAGECMLFKDGLYAAAAAAAAATAASSMGVTPF
What is the function of this protein?
May be involved in leaf cell growth and differentiation, rather than abaxial cell fate determination.
What are the official names of this protein?
Protein YABBY 5, OsYAB3, OsYABBY5.
What is the protein family that this protein belongs to?
Belongs to the YABBY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KBAY_ECO8A
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: PEPB_PIG
Sequence: MERIILRKGKSIREAMEEQGVLEKFLKNRPKIDPAAKYHFNNDAVAYEPFTNYLDSFYFGEISIGTP
What are the official names of this protein?
Pepsin B, Parapepsin I.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: H2A15_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.15, HNTX-II.15, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB_VEREI
Sequence: MTSYRQPDAAGHFGPYGGSFVSETLTLAIAQLRTAYARYQNDPEFLAEFGDELKHFVGRPAPIYHAARSSREIGGAQIYLKREDLNHTGAHKINNVIGQAMLARRMGKPRVIAETGAGQHGVAAATICARYGLECVVYMGAHDVRRQSPNVYRMKLLGATVVPVESGSRTLKDALNEAMRDWVTHVDDTFYIIGSVAGPHPYPMMVRDFQSIIGKECIEQMPAMLARNMAAGQQPDAVIACVGGGSNAMGIFHPYIPFAGTRLIGVEAAGLGLESGQHSASLQKGSPGVLHGSRTFVLQDANGQITETHSISAGLDYPGVGPEHAWLQQIGRAEYVGITDQEALDAFHFLCRTEGIIPALESSHAVAHALKLAKTMRPDQSILVNLSGRGDKDIGTVADLSGADFYCRPSCHGQSVKGASQ
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SOMA_DELDE
Sequence: MAAGPRTSMLLAFALLCLPWTQEVGAFPAMPLSSLFANAVLRAQHLHQLAADTYKEFERAYIPEGQRYSIQNTQAAFCFSETIPAPTGKDEAQQRSDVELLRFSLLLIQSWLGPVQFLSRVFTNSLVFGTSDRVYEKLKDLEEGIQALMRELEDGSPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity).
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MSHD_RHOJR
Sequence: MSASVQSWTDRLDGKQAADVSALLERATAADGTAPVSEQGVHAVSGAGSDGVRHLVETDADRIVGYAQLQPGRGDHPAMAELAVDPAARGRGIGGRLVAEVLSEGGPDARVWAHGNLPAAQAVAQRLGLIGARELLQLRRPLADAELPELVVPEDISLRVYRGVEDDPEVLRVNAAAFAWHPEQGSWTERELAERRAEAWFDPSGLFMAFAASDDQRLLGFHWTKVHPKQGDEPAIGEVYVVAIGPDAQGRGLGRLLTLAGLHYLRDRGLGAVLLYVEGDNESALHTYDRLGFERFHTDVAYARA
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: CAIB_ECODH
Sequence: MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLATHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_ECO57
Sequence: MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRDQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_NEIG2
Sequence: MAVQQNKKSPSKRGMHRSHDALTAPALFVDSTTGEVHRPHHISPNGMYRGRKVVKAKGE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ITM2B_PANTR
Sequence: MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAVETLICS
What is the function of this protein?
Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers.
What are the official names of this protein?
Integral membrane protein 2B, Immature BRI2, imBRI2, Transmembrane protein BRI, Bri.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
[Integral membrane protein 2B]: Golgi apparatus membrane; Single-pass type II membrane protein. Note=Immature BRI2 (imBRI2) is cleaved by furin in the Golgi into mBRI2 and a Bri23 peptide. mBRI2 is transported to the plasma membrane and Bri23 peptide is secreted. SUBCELLULAR LOCATION: [BRI2, membrane form]: Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Mature BRI2 (mBRI2) needs to be transported from the endoplasmic reticulum compartment to the cell membrane in order to be able to inhibit APP processing. SUBCELLULAR LOCATION: [Bri23 peptide]: Secreted. Note=Detected in the cerebral spinal fluid (CSF). SUBCELLULAR LOCATION: [BRI2C, soluble form]: Secreted.
Protein: FIMA1_SALTI
Sequence: MKHKLMTSTIASLMFVAGAAVAADPTPVSVSGGTIHFEGKLVYAACAVSTKSADQTVTLGQYRTASFTAIGDTTAQVPFSIVLNDCDPKVAATAAVAFSGQADNTNTNLLAVSSADNSTTATGVGIEILDNTSSPLKPDGATFSAKQALVEGTNTLRFTARYKATAAATPGQANADATFIMKYE
What is the function of this protein?
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
Type-1 fimbrial protein, A chain, Type-1A pilin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: IFT52_MOUSE
Sequence: MEKELRSTILFNAYKKEVFTTNTGYKSLQKRLRSNWKIQSLKDEITSEKLIGVKLWITAGPREKFTAAEFEVLKKYLDSGGDILVMLGEGGESRFDTNINFLLEEYGIMVNNDAVVRNVYYKYFHPKEALVSDGVLNREISRAAGKAVPGVIDEENSGNNAQALTFVYPFGATLSVMKPAVAVLSTGSVCFPLNRPILAFYHSKNQGFGKLAVLGSCHMFSDQYLDKEENSKIMDVVFQWLTTGDIHLNQIDAEDPEISDYTMVPDTATLSEQLRVCLQEGDENPRDFTTLFDLSIYQLDTTCLPKVIKAHEELNVKHEPLQLVQPQFEMPLPALQPAVFPPSFRELPPPPLELFDLDETFSSEKARLAQITNKCTDEDLEFYVRKCGDILGVTSKLPKDQQDAKHILEHIFFQVVEFKKLNQEAH
What is the function of this protein?
Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia (PubMed:19253336).  Required for the anterograde transport of IFT88 (By similarity).
What are the official names of this protein?
Intraflagellar transport protein 52 homolog, Protein NGD5.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: AKH1A_AGRIP
Sequence: MNYVSIFVLIVACLCVLADAQLTFTSSWGGGKRGAVAATMSCRSEETIAAIYKLIQNEAERLLLCQKP
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic prohormone type 1.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIBCH_XENTR
Sequence: MSLGLLESQLRLKVFGRLQVIRQHLRMTNHTVKDGECLLTKAGCAGVITLNRPKALNALNLGMIRLIYPQLGLWEEDPETYLVIIKGVGGKAFCAGGDIRAVTDAGKAGDRLAQDFFREEYILNNAIGTYKKPYVALIDGITMGGGVGLSVHGHFRVASENTLFAMPETAIGLFPDVGGGYFLPRLPGKLGLYLALTGFRLKGSDVQKAGIATHFVESEKIPSLEQDLVAMKCPSKENVADVLDSYHNKSYAAQDKPFVLAEHLDKINSLFSASSVEAIIENLRCDGSSFALKQLQTLSTMSPTSLKITFRQLKEGSSMSLQEVLTMEYRLSQACMKGYDFYEGVRAVLIDKNQNAKWNPELLEEVTDDYIDSYFTSLGNSDLKL
What is the function of this protein?
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite.  Has high activity toward isobutyryl-CoA.  Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.  Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity).
What are the official names of this protein?
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYI2_OCEIH
Sequence: MDHAQRERSMRAHWKENRTFQRSIENREGQQTYVFYEGPPTANGMPHAGHALGRTIKDFVARYKTMSGYQVLRKAGWDTHGLPVELEVEKQLNIRGKDDIEKFGVERFIEKCKESVFVYENEWKEFTDKLGYWVDMEDPYKTLNNPYIESVWNILATIHDEDLLYKGHRVVPYCPNCETSLSSHEVAQGYKDVTDLSVTAKFRIKNKENEYILGWTTTPWTLPGNVALAVNPEMTYVKAKQGEEIYVVAKSLANTVLGEAYEVVEEVSGEDLVGINYEAPFDFISLDNGHYVIGADFVTDTSGTGIVHLNPAHGEDDYNAIQAKGMDFVNVVDSKGRYEDVIAPLAGQFVKDSDVDIIKMLAKDGTLYEKQKYEHSYPHCWRCDTPLLYYAMEGWFIKTTAVKERMQENNQSVEWFPNHMRDGRFGNFLDNMVDWNIGRNRYWGTPLNVWVCDDCDKQKSPHSIQELRAFADSDVPEDIELHKPYVDKITFDCECGGKMHRTKEVIDVWFDSGSMPFAQYHHPFENDELFNKQFPADVVIEGVDQTRGWFYSLLAVSTLFTGKTPYKRVLSLGHILDEHGRKMSKSKGNALSPVELIEEFGADALRWALLADSSPWNNKRFSKKTVSQAKSKVIDTILNVYSFYSMYADIDKFNVAEHATDAKTTLDSWILSRLNSVIKEVTTSLDQYDITKGARSIALFVDELSNWYVRRSRQRFWSSGMNEDKKAAFTTLHEVLSKLTQLMAPYIPFVADDIYTNLQGDSVHVSDFPKVDEAAIDEKLEADMQGVLEVIEGARSLRNEVNIKTKQPLAELVVVPNDEQLQSGLQAYTSIIEEEINVKQVSFKKDTADFLDTEMKLNFPVAGPKLGKQVGQAKGKVENFTEQEKEAFLVNGTINVELQDGSEVTLEKEDIIVEKKGQEGYQLFEGNRFVLLLDTNLTEKLKEEGFVREFIRAVQTYRKELDLPVEQRVDIYVNSDENAERILSEFDALIHDGLIINSVQFAEKEDMKQVTVNDTEMGLSIV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase 2, Isoleucyl-tRNA synthetase 2, IleRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUR2_ASHGO
Sequence: MAEPDVSDTNTALKKSGEPGMELENNKATSGAVVTEAGFNTRKLWPDLIKLPSNRWVYSCKEIVDRLGTDPKAAQLTKKKMEKCLMYFYMIKKNLRLFDHTYTAACILFFRYWYIYELPQSLQDCIHLSQAILATACKAMENNRPLDMYVKATCEFMMKDLAQQQRGRQNMDKLKWDVRDKLVRYEKQLLCQFGFDLDLQNPKELIEEIFSGFYRFNRDNIMDEEFKKLFPKILAEARNFIIQAGTQPVSLLCDGYTFTALALLFAGLQYKRSTAPNFRFPRHFFQERFPIRITGPMIVNLFTDYRILEDNFFDLKSNKGDKLEVTNEEVQSLIDEEPTDETVPNPYDYELIKDGVCSQEFLDHTESKLKELTEKIISESLKKRPVIDDNTPKDDTKRVKM
What is the function of this protein?
Component of the BUR kinase complex involved in transcription regulation.  This complex phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes.  Also required for histone H3 methylation.  Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase.  The kinase activity of the complex requires the presence of BUR2.  Overexpression of BUR2 interferes with mitotic chromosome segregation (By similarity).
What are the official names of this protein?
Protein BUR2.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSH1_CITK8
Sequence: MIPDVSQALTWLERHPQALKGIQRGLERETLRVNADGTLATTGHPDALGSALTHKWVTTDFAEALLEFITPVDGDIQHMLTLMRDLHRYTARNLGDERMWPLSMPCYIAEGQDIELAQYGTSNIGRLKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVVDGEDAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSTEYAEIGLEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGETPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLKRVAQTLDSIHGGEDYQKVCDELVACFDNPELTFSARILRSMIDTGIGGTGKALGEAYRNLLREEPLEILREEDFIAEREASTRRQLEVEAADTEPFDAWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: QUEA_SINMW
Sequence: MRVDLFDFDLPEDSVALRPASPRDSARMLVVRPGGEPVLEDRGVLDLPSFLRQGDALVFNDTKVIPAQLEGVRYRGEHISTPVSLTLHMRVAPDRWKAFARPARRLKPGDRVSFGHGGNACLLGSLDAMVEEKGDAGEVTLRFDLSGPSLDEAIMSVGHIPLPPYIASKRADDARDRTDYQTVYAREEGAVAAPTAGLHFTDRLFAMLDEAGIERHFVTLHVGAGTFLPVKADDTDDHVMHEEIGHVDAVTAAKLNAVRERGGRVVCVGTTSLRLVESAAAEDGTIHAWSGATGIFITPGYRFRAAHMLMTNFHLPKSTLFMLVSAFAGLETMRDAYAHAIATGYRFYSYGDSSLLFRKD
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAT4_XENTR
Sequence: MAPTLATAHRRRWWMACTAVVENLFFSAVLLGWGSLLIMLKSEGFYSYLCHYPDNTTYHNSTGNETNQELVMDMNGWLICKEQDEMLNLAFTVGSFLLSAISLPLGIIMDKYGPRKLRLSGSASFGVSCLLIAYGASNPNSLSVLIFVALCLNGFGGMCMTFTSLTLPNMFGDLRSTFIALMIGSYASSAVTFPFIKVIYDLGVSFITILIVWAACAGLVFFNCFFNWPLEPFPGPEDMDYTVKIKFSWLGFDHKITGKQFYKQVTTVGRRLSVGGSMKNPKELSALQNGNKLCLSTVDLEVKCQADNAATPSFMKSVFSPILLLSLITMCVTQLRLIFYMGAMNNILEFLVEGDMDTVSLYTSIFGVLQLLCLLTAPVIGYIMDWKLKDCDDGKEDADEKDTNTDGKKKKKRDRQIQKITNATRAFAFTNFLLVGFGITCLINNLPLQILSFILHTIVRGFIHSAVGGLYAAVYPSTHFGSLTGLQSLISALFALLQQPLFLAMMGPLEGDPLWVNVGLLGVSMFGFCLPLYLIFYKRSLERQRKQKIEDSKLYLKINGTPDHEAFV
What is the function of this protein?
Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine.  The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent.
What are the official names of this protein?
Large neutral amino acids transporter small subunit 4, L-type amino acid transporter 4, Solute carrier family 43 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC43A transporter (TC 2.A.1.44) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SUCC_CHLTE
Sequence: MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAEQLFEEQSSPVVVVKAQIHAGGRGKAGGVKLAKSPEEVFEIAQKMLGATLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDRTTSSNVLMVSTEGGMEIEKVAEETPEKLLKIHVDPVYGLQGFQARKAAFFLGLQGEQFRNGVKFIEALYNAYTTIDASLAEINPLVITKEGRVLALDAKINFDDNALYRHSDFHDLRDITEEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLSGGRPANFLDVGGGASSKTVEEGFKIILGDKNVKAILVNIFGGIVRCDRVAGGIIEAAKNIGLKVPVIVRLEGTNATEAQKMLDESGLNLISAKGLRDAAEKVQKALATA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: KEFG_YERPN
Sequence: MLQPPKVLLLYAHPESQDSVANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRDHQVIVFQHPLYTYSCPALLKEWLDRVLARGFANGVGGHALTGKHWRSVITTGEQEGTYRIGGYNRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKPETLASHAQAYVQWLQSPLTRGL
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.