PharMolix/UniProtQA huggingface dataset:
Protein: SYP_METFK
Sequence: MRASQFFLATQKEAPQEAELASHKLMLRAGLIKRLGSGLYSWMPLGLRVLRKVETIVREEMNRAGALELLMPAVQPKELWEETGRWAVFGPQMLKIRDRHERDFCFGPTHEEVITDIARREIRSYKQLPLNFYQIQTKFRDEIRPRFGVMRAREFVMKDGYSFHTSLESLQQTYDTMYQAYSNIFNRLGLKFRAVRADTGAIGGDGSHEFHVLADSGEDALAYCEHSDFAANVELAEALAPEHPRGEPKEPLREVDTPKQTTCEDVAALLGISLQQTVKSIAVVATDEAGNSQFYLLLLRGDHALNEVKAAKVPGLSSFRFASELEIREYLGCPPGFIGPVGVSTQVNVVADRSVAVMSDFVCGANKPKLHLAGVNFGRDLPEPMIVADIRNVVEGDPSPDGKGCISLCRGIEVGHIFQLRTKYTEAMEATYLDENGQKQFMEMGCYGIGVSRIVGAAIEQGNDERGIIFPAAMAPFSVAIAPIGYDKSEAVQSAAHALYDELSALGIDVLLDDRGERPGVMFADLELIGIPHRIVIGDRGLKEGQVEYQARTAASAETVALADIVSIVRQAL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_ECOLU
Sequence: MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: RL24_ANAD2
Sequence: MAEIRKGDTVKVIAGKEKGKSGRVLEVLREDGRVRVEKLMTVKRHQKKGRSQANPEGGILEMAGTIAISSVMVVGKDEKPVRREKIGRELGAKEKARLQKRKTAAK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: P12_ASFB7
Sequence: MALDGSSGGGSNVETLLIVAIIVVIMAIMLYYFWWMPRQQKKCSKAEECTCNNGSCSLKTS
What are the official names of this protein?
Inner membrane protein p12, Protein p12.
What is the protein family that this protein belongs to?
Belongs to the asfivirus inner membrane protein p12 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Note=Part of the virion inner membrane.
Protein: TBP_PYRCJ
Sequence: MSSKGPSYRIENIVATVNLGVELDLESLAERLPMAEYNPDQFPGLILRLTKPRISALIFRTGKMVCTGAKNEEDLKNAVRALVKLLNDHGAEVPFDPEVQIQNIVASGNLHAEVDLEQAVFMLENAMYEPEQFPGLIYRMSSPRVVILIFGSGKIVCTGAKSEKDVATAVQKLYNQLKELGVLYIEEGGGEEEEEEEEM
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: PGDS_BACSU
Sequence: MNTLANWKKFLLVAVIICFLVPIMTKAEIAEADTSSELIVSEAKNLLGYQYKYGGETPKEGFDPSGLIQYVFSKADIHLPRSVNDQYKIGTAVKPENLKPGDILFFKKEGSTGTVPTHDALYIGDGQMVHSTQSKGVIITNYKKSSYWSGTYIGARRIAADPATADVPVVQEAEKYIGVPYVFGGSTPSEGFDCSGLVQYVFQQALGIYLPRSAEQQWAVGEKVAPQNIKPGDVVYFSNTYKTGISHAGIYAGAGRFIQASRSEKVTISYLSEDYWKSKMTGIRRFDNLTIPKENPIVSEATLYVGEVPYKQGGVTPETGFDTAGFVQYVYQKAAGISLPRYATSQYNAGTKIEKADLKPGDIVFFQSTSLNPSIYIGNGQVVHVTLSNGVTITNMNTSTYWKDKYAGSIRVQ
What is the function of this protein?
Cleaves, in an endo-type manner, the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA).
What are the official names of this protein?
Gamma-DL-glutamyl hydrolase, Poly-gamma-glutamate depolymerase, PGA depolymerase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall. Note=Cell wall localization shown in PubMed:11987133.
Protein: ADSSP_XENTR
Sequence: MAAAKKGAKPKVAGVRFAAGFPEEGAHNHVHFDEQLHDSVVMVSQQEDGNFLVKVGFLKILHKYEISFSLPPVQRLGKSICAVPLPTLNLKVLSITSQAEGHSIKCEYTAHKEGVLKEEMILASETNDKAFVKVVVQARVLDRHHGTPMLLEGVRCTGTELEYDSEQSDWHGFD
What is the function of this protein?
May be involved in thermogenesis and glucose homeostasis.
What are the official names of this protein?
Adipose-secreted signaling protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ADISSP family.
Protein: GP161_HUMAN
Sequence: MSLNSSLSCRKELSNLTEEEGGEGGVIITQFIAIIVITIFVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVYSANQCKALITILVVLGAFMVTWGPYMVVIASEALWGKSSVSPSLETWATWLSFASAVCHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQPLGHSSSTGDTGFSCSQDSGTDMMLLEDYTSDDNPPSHCTCPPKRRSSVTFEDEVEQIKEAAKNSILHVKAEVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLVTARTVPGGGFGGRRGSRTLVSQRLQLQSIEEGDVLAAEQR
What is the function of this protein?
Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development.  Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling.  In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling.  Its ligand is unknown (By similarity).
What are the official names of this protein?
G-protein coupled receptor 161, G-protein coupled receptor RE2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Mainly localizes to primary cilium in a TULP3 and IFT-A complex-dependent manner. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes and is apparently not degraded (By similarity).
Protein: Y125_VIBPA
Sequence: MNQLSESYKARLSNLLPSCVAFFKYLLKRLTHDRVNVNAGYLAYITLLSIVPMLTVLLSILSKFPVFANVGEVLQGYIIENFVPASGEAVHTALQEFVANTGKMSAVGGGFLFIAALMLISNIDKNLNYIWRVKDKRRLVFSFSMYWMVLTLGPILVGASIAATSYVTSLQILENETLSGAFNLFLRWLPLLLSFFAFLGLYILVPNKKVHLAHGAVGAAVAAILFELSKKGFALYITQFPSYQLIYGALAAIPILFVWVYLCWMIVLLGAEVTAALGEQEHWSEDLDMIHSSAESQLANEGSESSDSANSTSQ
What are the official names of this protein?
UPF0761 membrane protein VP0125.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR12_ATRBE
Sequence: MPTINQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL7_DEIDV
Sequence: MAYDKQALIDQLGQLTIMELADLIDGLKETWGVTAAVAAGPAAAGPAAAAEEKTEFDVVLVDAGASKINVIKEIRAITGLGLKEAKDMSEKGGVLKEGISKDDAEKIKAQLEGAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: UPS2_ARATH
Sequence: MYLVESKGGAIACMLLALLSLGTWPAVLTLLERRGRLPQHTYLDYSITNLLAAIIIAFTFGQIGSTKPDSPNFITQLAQDNWPSVMFAMAGGIVLSLGNLSTQYAWALVGLSVTEVITSSITVVIGSTLNYFLDDKINKAEILFPGVACFLIAVCLGSAVHRSNADDNKAKLRDFETAKQEASGPSTEIGTNSSKDLETNVTTKPKEGTARFLIELENTRAIKVFGKRKIIGLAITFFAGLCFSLFSPAFNLATNDQWNRLKQGVPKLVVYTAFFYFSVSCFIIALILNVVFLYYPVLGLPKSSFKAYLNDWNGRYWAFLAGFLCGFGNGLQFMGGQAAGYAAADSVQALPLVSTFWGVVLFGEYRRSSRKTYLLLFCMLFMFISAVAVLMASSGHRK
What is the function of this protein?
Proton-coupled transporter that transports a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, uric acid and xanthine, but not adenine.  Mediates high affinity transport of uracil and 5-fluorouracil (a toxic uracil analog).  Mediates transport of free pyrimidines and may function during early seedling development in salvage pathways, by the utilization of pyrimidines from seed storage tissue.
What are the official names of this protein?
Ureide permease 2, AtUPS2.
What is the protein family that this protein belongs to?
Belongs to the plant ureide permease (TC 2.A.7.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL11_METMA
Sequence: MTSIVEALVPGGKANPGPPLGPALGPLGVNIKEVVEKINEKTRDYNGMQVPVKVIVDDKKNVEIEVGTPPTASLVMKELGIQKGSGNAGSEVVGNLTIPQVAKIARMKKEDVLSYDLKATMKEVMGTCVPMGVNVEGMKAKDCQKALDEGKFDDLLANEAW
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DER_SYNPW
Sequence: MARPVVAIIGRPNVGKSTLVNRLCHSREAIVHDEPGVTRDRTYQDGYWGDRDFKVVDTGGLVFDDDSEFLPEIREQAALALEEASVALVIVDGQQGVTASDEAIAEFLRGQRCPALLAVNKCESPEQGLAMAAEFWSLGLGEPYPISAIHGAGTAELLDQVLTYLPPKSEEGDSEEPIQLAIIGRPNVGKSSLLNAICGEQRAIVSPIRGTTRDTIDTSLVRENRPWRLVDTAGIRRRRSVNYGPEFFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEEDGRACVVVVNKWDAVEKDSHTMTAMEKELRAKLYFLDWAPMLFTSALTGQRVDSIFALAALAVEQHRRRVSTSVVNEVLKEALSWRSPPTTRGGRQGRLYYGTQVASRPPSFTLFVNDPKLFGDTYRRYVERQIREGLGFDGTPLKLFWRGKQQRDAERDLARQQNRQG
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: MOBA_ALBFT
Sequence: MIPAQDITGLILAGGRGSRMGGVDKGLQTFNGMPLALHTLTRLQMGGGVGQIMINANRNLAAYESFGASVWPDGLADYAGPLAGFLTGLEHCETPFLVTVPCDTPRLPLDLVPRLAAALEAENADIAMVAAPEIGKDGQVRLRPQPVFCLLRVELLESLVRFTQEGGRKIDAWTALHKTAVAPFDLPHDDPLAFFNANTLAELHQLENNPA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 53DR_STAAC
Sequence: MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPYAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
What is the function of this protein?
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides.
What are the official names of this protein?
Putative 5'(3')-deoxyribonucleotidase.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
Protein: FLHA_BRUME
Sequence: MKQTLGAVPAARLTGTGPMSVAKQEADVQQAAAKPFIKGKFLTGSDIGLAVGIIIILTVLFLPVPAVVLDIGLAFSIAFSVLILMVALWIQRPLDFSAFPTVLLIATMMRLSLNIATTRVILTHGNEGYLAAGHVIHGFSQFVMGGDFVIGLVVFAILIIVNFLVITKGATRIAEVGARFTLDAIPGKQMAIDADLSSGLIDEKEAQRRRRELEEESSFFGSMDGASKFVRGDAIAGLIITAVNIFGGIVIGATRHGMDISQAADVFTKLSVGDGLVTQIPALIVSLAAGLLVSKGGTRGSADQAIFGQLGAYPKALLIAALLLFILGVMPGLPAFPFFLLGGAMAFVGIAVPRRQARQREADAAEAGKKQREAEEQERNSVKASLETNQIELCLGKQLSARLIASQEELAHRVNKMRRKFAQEYGFVIPEIKVTDDIALPPKSYRIKIHGTAVASHELRVGEILVVLGERPVPSVPGEEVREPAFGMRAYSVPETFTADLRREGYMTVDNLSVLLTHLSEIVRNNLAQLLSYKDMRILLDRLGPEYRKLLEDICPAHISYSGLQAVLKLLLAERISIRNLHLILEAIAEIAPLVRRPEMIVEHVRMRMAQQICGDLSDNGVLNVLRLGNRWDLVFHQSLKRDAKGEIVEFDIDPRLLEQFGTEASAAIRKHFDNGERFVLVSSPEARPYIRMIIERLFATLPVLSHVEIARGVEVKSLGAIS
What is the function of this protein?
Required for formation of the rod structure of the flagellar apparatus.  May constitute the export apparatus of flagellin (By similarity).  The flagellum is required to cause a persistent disease in a murine model of infection.
What are the official names of this protein?
Flagellar biosynthesis protein FlhA.
What is the protein family that this protein belongs to?
Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TTCA_ACIB5
Sequence: MYAPVESNEGFNFKPELPTSSAYYRLLKKLRRQVGHAIRDFNMIEDGDKVMVCVSGGKDSYTLLDILLQFKRIAPINFDIVAVNLDQKQPGFPEDVLPRYMEENNIPYYILEKDTYSITKRLTPEGKTYCAVCSRLRRGSLYGFAQEIGATKVALGHHRDDIIATFFLNLFHGGSLKAMPPKLLSSDKKNILIRPLAYVEEKDIIKYAELRKFPIIPCNLCGSQENLQRAMINEMLREWDKQYPKRLHSIFGALQNVSPSQLADRDLFDFEVLDSQRELDFKDPEELKKRLDVVNLSFAAE
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTA1_RAT
Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSSLIALADKHATLSVCYRAGPGADTGEEGEVEEEVENPEMVDLPEKLKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKDGEEDGRDQSKLETKVWEAHNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQISVNSVKASVVNGTGTPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNMSPHGIPARSSGSPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYMPINSAAIKAECTARLPEASQSPLVLKQVVRKPLEAVLRYLETHPRPPKPDPVKSSSSVLSSLTPAKSAPVINNGSPTILGKRSYEQHNGVDGLANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPLRPPPPAPVNDEPIVIED
What is the function of this protein?
Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator (By similarity).  Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (By similarity).  In the NuRD complex, regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA (By similarity).  In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A (By similarity).  Acts as a transcriptional coactivator of BCAS3, and SUMO2, independent of the NuRD complex (By similarity).  Stimulates the expression of WNT1 by inhibiting the expression of its transcriptional corepressor SIX3 ().  Regulates p53-dependent and -independent DNA repair processes following genotoxic stress (By similarity).  Regulates the stability and function of p53/TP53 by inhibiting its ubiquitination by COP1 and MDM2 thereby regulating the p53-dependent DNA repair (By similarity).  Plays a role in the regulation of the circadian clock and is essential for the generation and maintenance of circadian rhythms under constant light and for normal entrainment of behavior to light-dark (LD) cycles (By similarity).  Positively regulates the CLOCK-BMAL1 heterodimer mediated transcriptional activation of its own transcription and the transcription of CRY1 (By similarity).  Regulates deacetylation of BMAL1 by regulating SIRT1 expression, resulting in derepressing CRY1-mediated transcription repression (By similarity).  With TFCP2L1, promotes establishment and maintenance of pluripotency in embryonic stem cells (ESCs) and inhibits endoderm differentiation (By similarity).
What are the official names of this protein?
Metastasis-associated protein MTA1.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Nucleus envelope. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with microtubules. Localization at the nuclear envelope is TPR- dependent (By similarity). SUBCELLULAR LOCATION: [Isoform 2]: Rough endoplasmic reticulum. Golgi apparatus. Zymogen granule.
Protein: EFTS_CUPMC
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEADGDLGKAEELLRVKLGNKASKAASRVTAEGIVVSYIDGTTGALVELNCETDFVSKNDDFLGFGAKVAELVAKQNPADVAVLSALEMDGSTVDAVRSALIGKIGENMTIRRFVRYTNGGKLVSYLHGTRIGVMVEFDGDEAAAKDVAMHVAAMKPVSLSADQVPAELIAKERSIAEQKAAESGKPAEIVAKMVEGSVQKYLKEVSLLNQSFVKNDKQTVEQMLKGVNTTVKGFTLYVVGEGIEKKQDDFAAEVAAQVAAAQKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISLR_HUMAN
Sequence: MQELHLLWWALLLGLAQACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQLSYQPSQDGAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSPNVGTDGRALPGTPVASSQPRFQAFANGSLLIPDFGKLEEGTYSCLATNELGSAESSVDVALATPGEGGEDTLGRRFHGKAVEGKGCYTVDNEVQPSGPEDNVVIIYLSRAGNPEAAVAEGVPGQLPPGLLLLGQSLLLFFFLTSF
What are the official names of this protein?
Immunoglobulin superfamily containing leucine-rich repeat protein.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3415_CITK8
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAASAAKIVFVVGIVLFLISLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein CKO_03415.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VPS10_PHANO
Sequence: MKYLKGLLLPALLALAPSATAAKDAPSIETTTFSNELVNLQYFDDSTVALVQELGSGKIYRSPDAGKAWKELKDLKKGLGIIKNPYDNKVALVLGEEQHWITYDQGETWQDFKTEYSPSPNGPVSWHSQDNKKILIHEIEDCLFTPCLGLTYYTTDGFKTKPKTLVEGRRMCQWAKGSERFLEGQEKHDDRILCILRGKYSDRSKDFRLMISDDYFKTAEEPVMSSGRTVQGMANMAAVKGYLVAAVKADHSSELSLYVTQDTENWHHAQFGNGKIEEDAYTILESTNYSIQVDVMSSKYVSIGSLYTSNSDGLYFTKNVDNTNRNPDGFVDFEKIANIQGVVLVNIVDNAKAVQERGAHKKLKSRISFDDGRTFEELKVKGSDKELHLHSSPGIVMGVGNTGDELGKYTDGDLYVSDDAGLTWELALDEAHKYEFGDQGSVLVAVFDEGDTDKVMYSLKHGRKDTWKSIDLGYKIRARELTTLSDSTSLRFLLYGSKKKDGGGREHVLIQLDFNDLHERKCEDKDFDPKWSDPTPTFESCECDEFRDFECDFGFKPEGEGKDKKCVPEKLTLPKDACKNGDSTYMGSSGWRKISGNQCKGGSKKDEKTERKCDEADLPPPKSDKITSEITRFKGSNFLEQYYLERSTQNDDDETDHDETVVMLTDERTAWITHDHGKQWKKAVDDEVVRIYPHQYDNNYVYFLTASKKVHYSEDRGLRNSIHSFEAPVMPNQEMLQILQFHPKQKGWLIWMGGKNCEKVNSKECHTAAYVSQKNGKDESWEPLVSYVKKCAFVWREAGRDVKEERVFCEQHANEETGAPLQLISSDDWFKKQDVKFKSVVEIALMSEFIIVATKEKDDTLRLDASLDANTFAEARFPPKFFDIHQTAYTVLDSSTHAIFLHVTVNPRVDQEYGSIIKSNSNGTSYVLSLNAVNRNTEGYVDFEKMQGLEGVAIANVVVNVNEVNDGAKKKKQTRITHNDGADWREKDAEGKAYECAGKGEEKCALHVHGYTERADPREMYSSPTAVGLMLAVGNVGEELGTFGEADTYMTTDAGLTWKEIKKGSYAWEFGDQGSVIVIVRRGEDTDHVYYTLDSGEKWNLYQFSERKIRVDAITTVPSDTSLNFLLWGKDGKELVAVNLDFSGLPQFQRKCDLDEKDPEKGDFDLWIPQHPLQPDDKQCLFGHVAEYHRKKRDAECRNGQRIDHMHNIQRNCTCTRRDYECAYNYERQPGGECKLIEGLDLEDPTAVCSKGAKEFWDVSPYRKIPLSTCEGGNEFDHMGDVHPCPGFEEEFEKKHGISGFGLFMAIVLPFAAAGGIGYYVWRNWDGKFGRIRLGENGGAFDSDSRWVQWPIAAISGLVAVVAAIPMLVGSLYRMVTGRMGGGYGGRTYTSRSSFARGRGDYAVVDPDEGELLGDDSDEEV
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: RS8_MYCBO
Sequence: MTMTDPIADFLTRLRNANSAYHDEVSLPHSKLKANIAQILKNEGYISDFRTEDARVGKSLVIQLKYGPSRERSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAIISTSSGLLTDRQAARQGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GATA_SALAI
Sequence: MTDLTSLSAAELAGLVARGESSAAEVTQAHLDRITAVDDRVHAFLHVDTEGALDAARAVDARRAAGEPLGPLAGVPVAVKDVLTTKGIPTTAGSRILAGWRPPYDSTIVRRLRAAGTVMLGKTNMDEFAMGSSTEYSAFGPTHNPWDLSRIPGGSGGGSAAALAAYETPLSIGSDTGGSIRQPGAVTGTVGVKPTYGGTSRYGLVAFSSSLDTPGPCARTVLDAALLHEAIGGHDPSDSTSIPAPVPDVVAAARLGASGDLAGVRLGVVREFAGEGAEPGVLAAFRAAVDTLTKLGAEVVEVSCPHFQYALPAYYLIAPSECSSNLARFDGVRFGLRVGDDGNRSLEEVMSATREAGFGPEVKRRVVLGTYALSSGYYDAYYGQAQKVRTLITRDFTTAFEQVDALVSPTTPFVAFPVGARTADPYQMYLADLFTIPSNLYGGPGISVPCGLADGLPVGLQVMAPTMADDRMYRVAAALESAVGPFTPPAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.