PharMolix/UniProtQA huggingface dataset:
Protein: EXPB6_ORYSJ
Sequence: MAARMGSKVAAILAILSVLVVHGSCKGHPVNYNVSDASAYGSGWLPARATWYGAPTGAGPDDNGGACGFKNVNQYPFSSMTSCGNEPIFKDGKGCGSCYQIRCNKDPSCSGNIETVIITDMNYYPVARYHFDLSGTAFGAMAKPGLNDKLRHSGIIDIQFRRVPCNYPGLKINFHVEEGSNPVYFAVLVEYEDLDGDVVQVDLMESKSAYGGATGVWTPMRESWGSIWRLDSNHRLQAPFSLRIRSDSGKTLVANNVIPANWSPNSNYRSIVQFS
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-B6, Beta-expansin-6, OsEXPB6, OsaEXPb1.8.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: CLAG_PENCR
Sequence: MSSNSSCLVTNQGGALPLTATCLEGFYCPNNSLENPPEICPPTPQCRLTRLQEYHNICDHAQGTYEPIVCQPGFYCPSGGKRQIPCPKGHFCPLGTVEPFKCFGLSSCAEGSEREIPLAGLLCSILLDIFLVIVVSWPFPFAWIRQLSRGKLRRGAGGNDSESGVISAGRREISFSESKYHVSQFFTSDGSHGTAAGIEVEFSGISMRPTRSGIETLCLQNGVIRAGSFVGVMGPSGSGKSTLVKVLTGRAQPTTGSVLINGDTCRAAELRDLLALVPQDDIILPDLTVQENILYSSRVRIGSSRKDSEIEQYVDHLIISLGLNKVRNRLIGEVGKRGLSGGERKRVNIALELAAVPGIIVLDEPTSGLDAMTALSVIELLKSLTKQGVIVICVIHQPRLEIFAALDDLLLLNHGRQVYFGSAAAAKQCFQDAGYTFPLNSNPTDTMMDIMSCHDNLHLTDYPRNKPALPKQNLRIVLQSVKKIRAPWYCQVLLAFMRGTKQQTRQYPSFVLEILTGAGCGILIGLSNYEFKGHLFQGLFHLPFQLLSSPVSYRLLTEQGMLLCLTIGCAAGPAGVKTFGEEKLVFLRESCSGYSEGAYFLGKALSTLIRIFLSALHFTSFYLILTTPIVSFPNQLIVNLLYFYCIYGAASMISAITSPKNGPLITMLTSVLFCALSGCAPRLASVKSWNLAWLWYICPAVWIAEANFNQYTDPLAYLYDIKPAAEDAIRAWDRLSLHSLFIV
What is the function of this protein?
ABC-type transporter; part of the cla gene cluster that produces clavatol and ortho-quinone methide (PubMed:30811183).  The clavatol biosynthesis cluster cla and the terrestric acid cluster tra are both involved in the production of peniphenones and penilactones (PubMed:30811183).
What are the official names of this protein?
ABC-type transporter claG, Clavatol biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 1001R_ASFM2
Sequence: MVRLFHNPIKCLFYRGSRKTREKKLRKSLKKLNFYHPPGDCCQIYRLLENVPGGTYFITENMTNELIMIVKDSVDKKIKSVKLNFYGSYIKIHQHYYINIYMYLMRYTQIYKYPLICFNKYSYCNS
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 100-1R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 100 family.
Protein: RL34_BACFR
Sequence: MKRTFQPSNRKRKNKHGFRERMATANGRRVLAARRAKGRKKLTVSDEYNGVKA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DCUP_CAMJD
Sequence: MIFIDACFKKPTPYTPIWMMRQAGRYLPEYMEVRKQAGDFLSLCKDYKKASEVSLQPIDILNVDAAIIFSDILVVPLEMGMNLRFEKGEGPIFDNPISTLEDLEKLDDQNAHKKLNYVYNALKLTREKLSQNKALIGFCGSPWTIATYMIEGSGSKNYAKCKKMLYQNPELLHKILNKLTQVLKLYLEEQIKAGANAIQIFDSWASALEYDKFFEFSFSYMLEISNFIKSKYPNIPVILFPKGISGYLDRIDGNFDVFGVDWSTPLDLARDKLSHKYALQGNMEPCRLYDKNAIKEGVEKILKTMQNKAHIFNLGHGILPDIPVENAKYFIKLVQESSAK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO1_CUPMC
Sequence: MSAIVDIIGREVLDSRGNPTVECDVLLESGVMGRAAVPSGASTGSREAIELRDGDKSRYLGKGVLKAVEHINTEISEAIMGLDASEQAFLDRTLIELDGTENKGRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQMPVPMMNIVNGGAHANNSLDIQEFMIMPVSQTSFREALRCGAEVFHALKKILSDKGMSTAVGDEGGFAPNFSSNEECLNTVVQAIEKAGYKAGEDVLLALDCAASEFYHEAEGVYSLEGEGLKLTSTQFADYLANLCDKFPIVSIEDGMAEGDWEGWKTLTDKLGKRVQLVGDDLFVTNTKILKEGIEKGIGNSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGTNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIATYPGKSTFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 1, 2-phospho-D-glycerate hydro-lyase 1, 2-phosphoglycerate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PGK_STAAN
Sequence: MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP51_DICDI
Sequence: MIGTIAVLVIAILVIFAFKKSPSNIPPIVETIPFIGCFYQFAKNPLQLVRNSYDRLGEIFTLHLMGFKMTFVLGPEAQALFFRGTDEELSPKEAYRFVTPVFGKGVVYDSETEIMYEQLRFVKNGLVLSQLKKAVGIIQEETEKYFETKWGDSGEIDLLYEMNKLTILTASRCLMGKSINKSLGQSGQLADLYHELEEGLNPISFFFPNLPLPSFKKRDAARAKVAAIFHSIIQERRRSTDDSVDDVLYTLMNSKYKDGSVLEDEQIVGLMIGLLFAGQHTSSITLTYTIFYLLNNLEYFDETQKDINDIVQKENQGEINFDGLKRMNRLETVIREVLRLHPPLIFLMRKVMTPMEYKGKTIPAGHILAVSPQVGMRLPTVYKNPDSFEPKRFDVEDKTPFSFIAFGGGKHGCPGENFGILQIKTIWTVLSTKYNLEVGPVPPTDFTSLVAGPKGPCMVKYSKKQK
What is the function of this protein?
Sterol 14alpha-demethylase that plays a critical role in the third module of ergosterol biosynthesis pathway, being ergosterol the major sterol component in cell membranes that participates in a variety of functions.  Starting from lanosterol (lanosta-8,24-dien-3beta-ol), it catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of the sterol in the form of formate, and converts the sterol to 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol, which is critical for ergosterol biosynthesis.  Can demethylate susbtrates not intrinsic to yeast, such as eburicol (24-methylene-24,25-dihydrolanosterol) at a similar rate to lanosterol, and at a lower rate the 24,25-dihydrolanosterol (DHL) to 4,4-dimethyl-8,14-cholestadien-3beta-ol.
What are the official names of this protein?
Probable lanosterol 14-alpha demethylase, LDM, Cytochrome P450 51, Cytochrome P450-14DM, Sterol 14-demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: VM3C_CROAT
Sequence: NPCCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYSKDNSPGQNNPCKMLCSNEDEHKGRFLEQTGRGKVCSNRQ
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like catroriarin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UBP43_MOUSE
Sequence: MDPGVGNALGEGPPAPRPRRRRSLRRLLNRFLLALGSRSRSGDSPPRPPAQPSPYDGDGEGGFACAPGPAPASAGSPGPDRPPGSQPQISSGDGARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSAHGLVSEQLPPEVSKISEDLRPSAAPTSLGPSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPAEEVILVELYPNGFQRSFFDEEDLNTIAEGDNVYAFQVPPSPGLGTLSAHPSGLSVSPRLPVRDSQRFSGPLHSENRVVFLFCNLVGSGQQASRFGPPFLIREDRTISWAQLQQCILSKVRCLMRSEVSAQDLGTLFSIRVVGLSLACSYLSPKDNRPLCHWAVDRALHLRRPGGPPHVKLAVEWDSSVTERLFGSLQEERVQDADSVWRQQQAHQQPSCTLDECFQSYTKEEQLAQDDAWKCPHCQVLQQGVVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLSGLNMAPHVARRSTNSKAGPGPWSSWKQPICLPTTYPLDFLYDLYAVCNHHGSLQGGHYTAYCRNSLDGQWYSYDDSTVEALREDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLMRLGSLNNSTRGSLLSWSSAPCPSMARVPDSPVFTNGVCHQDKGGVETRPLVRGVGGRSISMKASPASRSRHGPFKTMPLRWSFGHREKRPGASVELVEYLESRRRPRSTSQSIVPLLTRAAGGEETSASPRSDGTLPAKSEDSGRAIGQGTTGVPLSSCHLNHHPALGSLDDSLHTARTRTGNVSQDIRLPKKFDLPLTVMPSVGDEKPARPEGQKMTPWKGSSQVGSQSSPPSPSTGLLRNFKDSGPGTLPKMKSKAAMEERAPDKDRGQGTFTLLKSVFWKKEHKRTVRTESSPPAPPISLGSDRLSPAAMNEQALRIRESPAKGLGNHMERDIRSAPSSLHLPRKASRPPRASTAGTSQRTIPGEQISYGTLQRVKYHTLSLGRKKSLPESSF
What is the function of this protein?
May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 43, Deubiquitinating enzyme 43, Ubiquitin thioesterase 43, Ubiquitin-specific-processing protease 43.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: CH60_POLSJ
Sequence: MAAKDVIFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDIAGDGTTTATVLAQAIVREGMKYVAAGMNPMDLKRGIDKAVTALVEELKKASKATTTSKEIAQVGSISANSDEAIGKIIADAMDKVGKEGVITVEDGKSLESELDVVEGMQFDRGYLSPYFINNPEKQSAILDNPFVLLYDKKISNIRDLLPTLEQVAKAGRPLLIIAEEVEGEALATLVVNTLRGILKVVAVKAPGFGDRRKAMLEDIACLTGGKVIAEEVGMSLEKVTLADLGTAKRIEVGKENTIIIDGAGEAKDIEARVKQVRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALLRAKQAAGAIKGDNADQEAGIKLVLRAIEAPLREIVYNAGGEASVVVNAVLAGKGNYGFNAANDTYGDMIEMGILDPTKVTRTALQNAASVASLMLTTEAMVAEAPKDESGAGGGMPGGMGGMGGMGDMGM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_AZOPC
Sequence: MFHLDFVTNWINKFLQKYLIDGWVLLVEFVLIAFVILIAYAVLALLLIYLERKVCAFFQCRLGPTRVGPWGIFQSVADMIKILLKELIRINKVDVCLFHLATYIVIIASICTFGAIPFDKGLHVVDFNIGVFYLLSVSSIGVVGILLAGWASNNKYTIIGAIRSGAQLISYELSCGLSLMTVVMLSGSLQLSSIVEQQSCGWNIVRGGIPAIIAFIIYLIAGHAETNRGPFDLPEAESELTAGYHTEYSGIQFGFFYLAEYLNMFIIAAIATTLFLGGWMPLHIPGWNLFNEVMDFIPSILWFFVKTFICIFLALWVRWTMPRLRIDQLLNLEWKILMPISLINIILMAFWIIYL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAZ_BACTN
Sequence: MIRFLGNIEVRADAKGRVFIPATFRKQLQAASEERLIMRKDVFQDCLTLYPESVWNEELNELRSRLNKWNSKHQLIFRQFVSDVEVVTPDSNGRILIPKRYLQICNIRGDIRFIGIDNKIEIWAKERAEQPFMSPEEFGAALEEIMNDENRQDGER
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DCUP_BACP2
Sequence: MGKTKAFNDTFLKACKGEKTDHVPAWYMRQAGRSQPEYRALKEKYGLFEITHQPELCAYVTRLPVEQYGVDAAILYKDIMTPLPAIGVDVEIKNGIGPVIDSPIRTKADIERLGELHPEEDLPYVLDTIQLLTKEQLNVPLIGFAGAPFTMASYMIEGGPSKNYHKTKALMYSEPETWMLLMNKLADMTITYIRAQVKAGVSAFQIFDSWVGALNAADYRTFIKPVMQRIFTELKSENVPMIMYGVGASHLVKDWHDLPLDVVGLDWRMSVDEARKEGLTKTLQGNLDPTILLSPWEVIEERAKDILDQGMKSDHFIFNLGHGVFPDVSPDTLKKLTDFIHDYSAKHKKSSI
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_STAAM
Sequence: MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEAHPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLIVLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETINAIYYQMQIASQYLYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGLIIVGDMQHQEVDQILTYSTIYDLPILADPLSHLRKFDHPNVICTYDLLFRSGLDLNVDFVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLMEDTTINRVSWLEKWQCLEKKGRKEIKCYLEQATDESAFVGELIKKTSEKDALFISNSMPIRDVDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKRITLLIGDLSFYHDMNGLLMSKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFKRFNSVSEFKNATLLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: FTHS1_STRP8
Sequence: MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLLLVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALAKTAVRVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 1, Formyltetrahydrofolate synthetase 1, FHS 1, FTHFS 1.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: ASSY_CLOBK
Sequence: MKEKVVLAYSGGLDTSIIIPWLKENYDLDVIAVCVNVGQGDDMDYVKTKAIKSGASKIYVEDVKEEFVVDYLYKAIKSEALYEQDYMLGTSFARPLMAKKLVEIAHKEQAKYICHGCTGKGNDQVRFEVGVKAQDPTIKIIAPWRIWDIKSREDAIDYAKKVGVEVPVTKKKIYSVDRNLWHVSHEGGDLEDLKNEHKEDMYFMVTPPEKAKDEPTYLEIYFEKGAPVKINGEFLNPVDIIDKLNTIGGENGIGIADIIENRLVGMKSRGIYETPAGTLLYAAHKKLESVTLDKYTYQYKKLVSAQYGELVYNGLWFTALREAIDAFVDKTQENVTGTVKLKLYKGNIKPCSVDTEYALYDEGISSFGESELYSHKDAEGFINLFGLPCKIKALKNF
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_ECOHS
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RL34_SULIA
Sequence: MPRPALRSRSLRRIYVKLPSGKTAIHYERKKNDIPKCAMCKKPLHGVKTNFLHKYGKSEKRPERPFGGYLCSSCLAQLIKAMVRQ
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: S15A2_HUMAN
Sequence: MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSYYGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFDFVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLNLADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHSVQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIEDIPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMIKLETKKTKL
What is the function of this protein?
Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:7756356, PubMed:18367661).  Transports the dipeptide-like aminopeptidase inhibitor bestatin (By similarity).  Can also transport the aminocephalosporin antibiotic cefadroxil (By similarity).  Also able to transport carnosine (PubMed:31073693).  Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs) (By similarity).  Probably acts by mediating transport of bacterial peptidoglycans across the plasma membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).
What are the official names of this protein?
Solute carrier family 15 member 2, Kidney H(+)/peptide cotransporter, Oligopeptide transporter, kidney isoform, Peptide transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPLB_BACSU
Sequence: METVPKKRDAPVLTAGKGISWMAALKRDKWLYLLLIPGLLYFLIFKYLPMWGVLIAFKDYSPYLGFWKSEWVGFDYFKDFFMNPDFFRLLRNTLMLASLDLLFAFPAPLILALLLNEVRKAVYKRCIQTFIYVPHFVSWTIVVSITFVFFTVDTGVINKLIMSLTGEQISFLSDADWFRPMIVMQSIWKETGWGTILFLAALATVDQEQYEAAIMDGAGRFRRMWHITLPAIRSTIIVLLILRIGSFLNLGFEQVYLMTNSLNRSVADIFDTYVYMMGITQGAYSYSTAVGLFKSVVGIILIFGANYIAKKFDQEGLF
What are the official names of this protein?
Protein LplB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXT_LISMO
Sequence: MKKIGVLAIQGAVDEHIQMIESAGALAFKVKHSNDLAGLDGLVLPGGESTTMRKIMKRYDLMEPVKAFASKGKAIFGTCAGLVLLSKEIEGGEESLGLIEATAIRNGFGRQKESFEAELNVEAFGEPAFEAIFIRAPYLIEPSNEVAVLATVENRIVAAKQANILVTAFHPELTNDNRWMNYFLEKMV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: FTSL_SHEON
Sequence: MSKPSLTLPRIVLHDLWQHKWILLLALLVLSNAVAVVYTSHVSRKLTTEWDQLLQERDRLDIEWRNLLLEEQSQTEHSRITRIASKDLNMSRPLPSEEIVVKVP
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: BIOW_STAA3
Sequence: MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFAAAKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: AB17G_ARATH
Sequence: MLQRDAVIDVDESEIPPIPFVLAFNDLTYNVTLQQRFGLRFGHSPAKIKTLLNGITGEAKEGEILAILGASGAGKSTLIDALAGQIAEGSLKGTVTLNGEALQSRLLRVISAYVMQEDLLFPMLTVEETLMFAAEFRLPRSLSKSKKRNRVETLIDQLGLTTVKNTVIGDEGHRGVSGGERRRVSIGTDIIHDPIVLFLDEPTSGLDSTSAFMVVQVLKKIARSGSIVIMSIHQPSGRIMEFLDRVIVLSSGQIVFSDSPATLPLFFSEFGSPIPEKENIAEFTLDLIKDLEGSPEGTRGLVEFNRNWQHRKLRVSQEPHHNSSSLGEAINASISRGKLVSTSYRSIPSYVNPWWVETVILAKRYMINWTRTPELIGTRVFIVMMTGFLLATVYWKVDDSPRGVQERLSFFSFAMATMFYSCADGLPAFIQERYIFLRETAHNAYRRSSYVISHSLVTLPHLFALSIGFAATTFWFVGLNGGLAGFIYYLMIIFASFWSGCSFVTFVSGVIPNVMMSYMVTFGYLSYCLLFSGFYVNRDRIHLYWIWIHYISLLKYPYEAVLHNEFDDPSRCFVRGNQVFDNTIMEGVSETTKAKLLETMSGYLGMELTESTCLTTGSDLLKQHGIEQLDKWGCLWVTLAWGFFFRILFYFSLLLGSKNKRA
What are the official names of this protein?
ABC transporter G family member 17, ABC transporter ABCG.17, AtABCG17, Probable white-brown complex homolog protein 17, AtWBC17.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.