PharMolix/UniProtQA huggingface dataset:
Protein: KYNB_BURP6
Sequence: MDTIWDISPPIAPATPVWPGDTPVGIERVWRIEAGSPVNVARVTLSPHTGAHADAPLHYDADGAPIGAVPLDAYLGRCRVIHCIGARSAVTPGHVRAALDGAPPRVLLRTYGQAPQHAWDSAFCAVAPETIDLLAAHGVRLVGIDTPSLDPQESKTMDAHRRIRAHRMAILEGLVLDEIAAGDYELIALPLKFATLDASPVRAVLRALPAAPR
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: GCST_STAAR
Sequence: MSSDLKQTPLYQNYVDRGAKIVEFGGWAMPVQFSSIKEEHNAVRYEIGLFDVSHMGEIEVTGKDASQFVQYLLSNDTDNLTTSKALYTALCNEEGGIIDDLVIYKLADDNYLLVVNAANTEKDFNWILKHKEKFDVEVQNVSNQYGQLAIQGPKARDLINQLVDEDVTEMKMFEFKQGVKLFGAIVILSQSGYTGEDGFEIYCNIDDTEKIWDGLLEYNVMPCGLGARDTLRLEAGLPLHGQDLTESITPYEGGIAFASKPLIDADFIGKSVLKDQKENGAPRRTVGLELLEKGIARTGYEVMDLDGNIIGEVTSGTQSPSSGKSIALAMIKRDEFEMGRELLVQVRKRQLKAKIVKKNQIDK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: REX_STAAW
Sequence: MSDQVKIPRATLKRLPLYYRFVSSLKSKGIDRVNSKAISDALQIDSATIRRDFSYFGELGKKGYGYNIDSLLDFFKSELSESDMIKIAIVGVGNLGKALLTYNFSIHDDMTITEAFDVKEDVIGQKIGNVIVKDNDELITTLKKEEIDVVILTTPERVAQKVADELVQAGVKGILNFTPGRINTPSDVQVHQIDLGIELQSLLFFMKNYSE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_PSEPF
Sequence: MNLFDFFRANKKPSTASVAKERLQIIVAHERGQRSTPDYLPSLQKELVEVIRKYVNIGNDDVHVALESQGSCSILELNITLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: NK2R_CAVPO
Sequence: MGACVIVTNTNISSGLESNTTGITAFSMPTWQLALWATAYLALVLVAVTGNATVTWIILAHQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAIDRYMAIVHPFQPRLSAPSTKAVIGGIWLVALALAFPQCFYSTITEDEGATKCVVAWPEDSRDKSLLLYHLVVIVLIYLLPLTVMFVAYSIIGLTLWRRAVPRHQAHGANLRHLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNRRFRSGFRLAFRCCPWVTPTEEDKLELTHTPSFSLRVNRCHTKEILFMAGDTVPSEATNGQAGGPQDRESVELSSLPGCRAGPSILAKASS
What is the function of this protein?
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A).  It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Substance-K receptor, SKR, NK-2 receptor, NK-2R, Neurokinin A receptor, Tachykinin receptor 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GAM_BPMU
Sequence: MAKPAKRIKSAAAAYVPQNRDAVITDIKRIGDLQREASRLETEMNDAIAEITEKFAARIAPIKTDIETLSKGVQGWCEANRDELTNGGKVKTANLVTGDVSWRVRPPSVSIRGMDAVMETLERLGLQRFIRTKQEINKEAILLEPKAVAGVAGITVKSGIEDFSIIPFEQEAGI
What is the function of this protein?
Protects linear double-stranded DNA from host exonuclease degradation.  Binds to linear dsDNA irrespective of the precise architecture of the DNA terminus but not to RNA or to ssDNA.
What are the official names of this protein?
Putative DNA ends protecting protein gam, Gene product 10, gp10.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: ARGC_EXIS2
Sequence: MKCTIVGATGYAAIELIRLIELHPHLEIVSLISDSQTNQEMNDLYSFMNNKQFPVLTAFSLEQIEAVETDLLFLATPSGISTKYLKQLDDWKGTVIDLSGDLRLEKSLYEKWYPHESVDTVLQKKATYGLTEWKREQIKDSRLIANPGCYATAVLLGLLPLLEERVIDPSQIIIHASSGLSGAGKTLTEQTHHVRSSENVRLYKMNQHQHIPEIESIAEDITGQQITVSLATYLVPLNRGIMATMTLQPLVEKTEAEWRTWFIEKYKQESFIRVGQTDPEIKSAAGSNYCDISVYLDTRTGRLTVVSVLDNMQKGAAGQAIQNANVIGGYPETLGLTQQPFFI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_CAMJR
Sequence: MADITDIKTILYTEKSLNLQEQGVVVIQTSPKMTKTGLKAVLKEYFGVTPKSINSLRMDGKIKRFRGRLGQRNNYKKFYVKLPEGVSLENTEA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: UVRB_RICBR
Sequence: MSNFSIISDYKPAGDQPKAIDEIIKGLNNKKRSQMLLGITGSGKTFTMANIIERTNRPTLIMAHNKTLAAQIYSEMKSIFPKNAVEYFVSYYDYYQPEAYIPKTDVFIEKDSSINEQIDLMRHSATRSLLERRDVIVVSSVSCIYGLGSPDLYYQMTVNLEPGKSYPRDKLLNDLVNLQYERNDIGFERGCFRVKGDNVDVFPSHYSDKAWRLSFFGNELEYIHEFDPLTGEKLVKLDKAIIYGNSHFVMPKETVNKAISEIEEELQKRIAFLKSQDKLLETQRINQRTQYDLEMLTETGSCKGVENYSRFFTGRKAGEPPPTLFEYLPKDALLFVDESHVSVPQIRAMYNGDRARKEVLVEHGFRLPSALDNRPLKFEEWDNFRPQTVFVSATPSLFELNETGGEVVELIIRPTGLLDPECIIKPATNQVEDLVGEIQSTIAKGFCVLVTTLTKKMAEDLTNYLQELKYKTSYLHSNIHTLERIEILRDLRQGTIDILVGINLLREGLDIPECGLVAILDADKEGFLRSEVSLIQTIGRAARNSEGRVILYADKMTKSIDKAISETMRRRTIQQEHNEKYGIIPKTINRTIHALAELEKVDSKLDKKQTHNLFENPAKLKAHIDKLRKEMLKAASNLEFEQAAKLRDQLKTLEEAALELS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACG_STRMU
Sequence: MSKTLPKDFIFGGATAAYQAEGATHADGKGPVAWDKYLEDNYWYTAEPASDFYHQYPVDLKLAEEFGVNGIRISIAWSRIFPKGYGAVNPKGLAFYHNLFAECHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVNYAEFCFKEFPEVNYWTTFNEIGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVAHSKAVKLFKDGGYSGEIGVVHALPTKYPYDPNNPADIRAAELEDIIHNKFILDATYLGKYSEKTMEGVNHILAVNGGQLDLREEDFAALEAAKDLNDFLGINYYMSDWMRAFDGETEITHNAKGEKGSSKYQIKGVGRREAPVNVPKTDWDWIIYPQGLYDQIMRVKQDYPNYKKIYITENGLGYKDEFVNHTVYDDARIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERYPKKSAYWYKKLAETQIID
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: TBB_AJECA
Sequence: MREIVHLQTGQCGNQIGAAFWQTISGEHGVDGAGYYNGSLDIQLERMNVYFNEAAEKKYVPRAVLVDLEPGTMDSVRAGPFGQLFRPDNFVFVQSGAGNTWAKGHYTEGSELVDQVIDVVRREAERCDCLQGFQIIHSLGGGTGAGMGTLLISKIREEFPDRMMATFSSVVPSPKVSDTVVEPYNATLSNHQLVENSDETFCIDNEALYDICMRTLKLSEPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAYSFRVVTVPELTQKMYDPKNMMCLLDFRNGRYLTASAIFRGKVSMKEVEDQMRNVQNKNHTYFVEWIPNNVQTALCSIPPRGLKMSSTFVENSTAIQELFKRVGDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASISEGEDEYFDYAWAM
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GRP2_PHAVU
Sequence: MATIHRLPSLVFLVLLALGVCSARRALLTLDAGYGLGHGTGGGYGGAAGSYGGGGGGGSGGGGGYAGEHGVVGYGGGSGGGQGGGVGYGGDQGAGYGGGGGSGGGGGVAYGGGGERGGYGGGQGGGAGGGYGAGGEHGIGYGGGGGSGAGGGGGYNAGGAQGGGYGTGGGAGGGGGGGGDHGGGYGGGQGAGGGAGGGYGGGGEHGGGGGGGQGGGAGGGYGAGGEHGGGAGGGQGGGAGGGYGAGGEHGGGAGGGQGGGAGGGYGAGGEHGGGAGGGQGGGAGGGYGAGGEHGGGAGGGQGGGAGGGYGAGGEHGGGGGGGQGGGAGGGYAAVGEHGGGYGGGQGGGDGGGYGTGGEHGGGYGGGQGGGAGGGYGTGGEHGGGYGGGQGGGGGYGAGGDHGAAGYGGGEGGGGGSGGGYGDGGAHGGGYGGGAGGGGGYGAGGAHGGGYGGGGGIGGGHGGNVP
What is the function of this protein?
Responsible for plasticity of the cell wall.
What are the official names of this protein?
Glycine-rich cell wall structural protein 1.8, GRP 1.8.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ACEK_SALDC
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWETLLMRILSDLPLRLPWQNKSRDIRYIIAHLTETLGEDALPCCHVQVANELFYRNKAAWLVGKLTTPDGTLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRVFKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMALLRQEAPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRRQRFSVRYGAISSTANSS
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO21_VIBVY
Sequence: MSLSITHEKSLIDNYIWILFDKSKAIVIDPGESEKIINFLDKNNLTLEFIFLTHGHCDHTKGVFSLKEKFPNASLFVPIGLELGLGESIIKEGDELNLLNSTFNVLELPGHTDNHIGIMYKDNLFCGDVLFSAGCGRVGSNYKDMYLSLKKIKSMDDKTKIYFSHEYTLDNLKFAHYIDPKNKNIINYIEVFKEKPDTVSAPTTLLLEKEINPFLRLSENIDIKNKINNEFDAFVYLRKLKDKFNSI
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase 1, Glyoxalase II 1, Glx II 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: TM256_DANRE
Sequence: MNAASLVQRVAGISGALAVAAGAYGAHGFRRSEASDYQRELFDTANKYHFYHSLALLGAARCRKPALAGVILLTGMGCFCGPLYHQPLTNDPSFSKLAPIGGSLLIVGWAAMAL
What are the official names of this protein?
Transmembrane protein 256.
What is the protein family that this protein belongs to?
Belongs to the TMEM256 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MTNC_SHEPW
Sequence: MGIRAIVVDTAGTTTDLNFIEDILFPYSAKVLPAFLEENQKNVLVENCICDVQDIALEPDADLARVTEILLQWIEEDRKATPLKTIQGLIWKQGYANGEFKGHIFPDFIEALDGYKQQGLRVYSFSSGSVDAQKLLFGNSDAGDLTDKFNGHFDTRTGNKRFKQAYCNILNTISLSPKQILFVSDVLEELKAASEAGLNVLQMVRQDNQRTGDFKQISSFAEIEL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: R9BP_DANRE
Sequence: MNRWQRSVVEIQTRKRQVNECERAQVALSKVTACFQQMSTSLGSNVDGSFLREEMEETRTVAHKICSGLHRRLLSLLMEIDQGQEDKEQVERLWVIFLSSLENFQQDLKKVKVLQEIFPLTQRKDRQALVITGLAGGTSEVAARAAMVQTPWLSVEVTVSPDLKTHIEEIDVLLEEMLQRVNVPLWSVEPTQEAWVEGSSTPGVGQEEDESLEEMMEVEVVSQNKTSGCCHHHNCKVGCLLCLLS
What is the function of this protein?
Regulator of G protein-coupled receptor (GPCR) signaling.  Probably acts by regulating the activity of some 'R7' family protein (RGS6, RGS7, RGS9 and/or RGS11).
What are the official names of this protein?
Regulator of G-protein signaling 9-binding protein, RGS9-anchoring protein.
What is the protein family that this protein belongs to?
Belongs to the RGS7BP/RGS9BP family.
Protein: PSUG_CUPPJ
Sequence: MSTDLAQSWLTLSAPVAAARAAGRPLVALESTIIAHGMPYPENVRTAHEVEALILELGAEPATIALIDGRIRVGLSDDELERLGRSGKAHKVSRRDLPAVLTSGELGATTVAGTMICAALAGIEVFVTGGIGGVHRGAQETFDISADLQELARTSVAVVCAGAKSILDIGLTLEYLETQGVPVLTCEQENFAAFYKRDSGFRADYRLDDPAEQARFIRTKWDLGLAGGVLLSTPVPEAAAMASEEIDALTQQALDEAQAQGITGKAVTPFLLARIKALTGGRSLATNIALVKHNAEVGARLALALAQAARGAVA
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: VSP_NAJNA
Sequence: IGGFECNEHEHRSLVYLYNSAGFFCAGTLLNHEWVV
What is the function of this protein?
Thrombin-like snake venom serine protease.  Shows strong hydrolytic activity towards Boc-Asp(oBzl)-Pro-Arg-MCA, a synthetic substrate for thrombin.
What are the official names of this protein?
Thrombin-like enzyme TLP, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FM522_NEOFI
Sequence: MTMTTAAVFGCTGAVGSQILATLLAIDTFPSVKTISRRLPNVQSPKLEAIEEGDSSKWGGMISSFSPKPSVVFNAVGTTRAAAGGLQNQWKIDHDLCIENARAAKEAGVKTYVFISGAGIRGFVARYLPFSKMKIGVEDAIKDLDFEHAIILRPGMIIGRENPKSALLENIVGGLNKLGQGIQDSLGQDQTVIARAAVAAARMADEGKAPSKYWVVEMADIVRLGRDEWKE
What are the official names of this protein?
Protein fmp52-2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: SPL4_ORYSJ
Sequence: MDWMPPPKPTSPRSPPLLWDWADAAVPGSSSGEVSAAAAAAAAHPGRRRKEKRGRAEEGGGGGGEVRCQVEGCGVELVGVKDYHRKHRVCEAHSKFPRVVVAGQERRFCQQCSRFHALSEFDQKKRSCRRRLYDHNARRRKPQTDVFSYASARPPSSLLFDDNRQISFVWNKAPLSHVRPFAISPWESSSEVGTTDGHIYLDKSHISKSLPAFNTDIDELLPMKDFSAATIWMFFGVLFIRTAQESCMSFH
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3' (By similarity).  May be involved in panicle development.
What are the official names of this protein?
Squamosa promoter-binding-like protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: ERPA_VIBC3
Sequence: MSEVNVPLSFSDAAAKRVKALIAEEENPSLMLRVYITGGGCSGFQYGFTFDETVNEGDTKIENSGVILVVDPMSLQYLIGGVVDYTEGLEGSRFFVNNPNATTTCGCGASFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: SUCC_SALSV
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIGKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: HPRK_STAES
Sequence: MLTTDRLVNTLNLELLTGEEGLDRPIKNTDISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDEEKKGRMRKLCRPETPAIIVTRGLEPPEELIQASQETHTPIIVAKDATTSLMSRLTTFLEHELAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIKEITKDELVGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKQIRLNINLENWNKNKLYDRVGLNEETLKILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAVEFNERLNEEIVRNSHKSEE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: SYP_SALCH
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLVRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDIVFSDVSDYAANIELAEAIAPQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAAKDSKSTLVALLVRGDHELNEVKAEKLPHVASPLTFATEEEIRAVINAGPGSLGPVNMPIPVIIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNFDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLMDDRKERPGVMFADMELIGIPHTIVIGDRNLDNDDIEYKYRRSGKKSLIKTGDIVDYLVKAIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_ACHLI
Sequence: MARVKNTPVTRRRRKKILKLAKGYFGSKSTLYRTAHEQVMRALQYAYRDRKQNKRNFRRLWISRINAGAVQNGFKYSKLIHGLSLANVQLNRKVLADLAISEPTVFASYVELAKDAIANPAKYQVK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: VITA2_XENLA
Sequence: MKGIVLALLLALAGSERTHIEPVFSESKISVYNYEAVILNGFPESGLSRAGIKINCKVEISAYAQRSYFLKIQSPEIKEYNGVWPKDPFTRSSKLTQALAEQLTKPARFEYSNGRVGDIFVADDVSDTVANIYRGILNLLQVTIKKSQDVYDLQESSVGGICHTRYVIQEDKRGDQIRIIKSTDFNNCQDKVSKTIGLELAEFCHSCKQLNRVIQGAATYTYKLKGRDQGTVIMEVTARQVLQVTPFAERHGAATMESRQVLAWVGSKSGQLTPPQIQLKNRGNLHYQFASELHQMPIHLMKTKSPEAQAVEVLQHLVQDTQQHIREDAPAKFLQLVQLLRASNFENLQALWKQFAQRTQYRRCLLDALPMAGTVDCLKFIKQLIHNEELTTQEAAVLITFAMRSARPGQRNFQISADLVQDSKVQKYSTVHKAAILAYGTMVRRYCDQLSSCPEHALEPLHELAAEAANKGHYEDIALALKALGNAGQPESIKRIQKFLPGFSSSADQLPVRIQTDAVMALRNIAKEDPRKVQEILLQIFMDRDVRTEVRMMACLALFETRPGLATVTAIANVAARESKTNLQLASFTFSQMKALSKSSVPHLEPLAAACSVALKILNPSLDNLGYRYSKVMRVDTFKYNLMAGAAAKVFIMNSANTMFPVFILAKFREYTSLVENDDIEIGIRGEGIEEFLRKQNIQFANFPMRKKISQIVKSLLGFKGLPSQVPLISGYIKLFGQEIAFTELNKEVIQNTIQALNQPAERHTMIRNVLNKLLNGVVGQYARRWMTWEYRHIIPTTVGLPAELSLYQSAIVHAAVNSDVKVKPTPSGDFSAAQLLESQIQLNGEVKPSVLVHTVATMGINSPLFQAGIEFHGKVHAHLPAKFTAFLDMKDRNFKIETPPFQQENHLVEIRAQTFAFTRNIADLDSARKTLVVPRNNEQNILKKHFETTGRTSAEGASMMEDSSEMGPKKYSAEPGHHQYAPNINSYDACTKFSKAGVHLCIQCKTHNAASRRNTIFYQAVGEHDFKLTMKPAHTEGAIEKLQLEITAGPKAASKIMGLVEVEGTEGEPMDETAVTKRLKMILGIDESRKDTNETALYRSKQKKKNKIHNRRLDAEVVEARKQQSSLSSSSSSSSSSSSSSSSSSSSSSSSSPSSSSSSSYSKRSKRREHNPHHQRESSSSSSQEQNKKRNLQENRKHGQKGMSSSSSSSSSSSSSSSSSSSSSSSSSSSSEENRPHKNRQHDNKQAKMQSNQHQQKKNKFSESSSSSSSSSSSEMWNKKKHHRNFYDLNFRRTARTKGTEHRGSRLSSSSESSSSSSESAYRHKAKFLGDKEPPVLVVTFKAVRNDNTKQGYQMVVYQEYHSSKQQIQAYVMDISKTRWAACFDAVVVNPHEAQASLKWGQNCQDYKINMKAETGNFGNQPALRVTANWPKIPSKWKSTGKVVGEYVPGAMYMMGFQGEYKRNSQRQVKLVFALSSPRTCDVVIRIPRLTVYYRALRLPVPIPVGHHAKENVLQTPTWNIFAEAPKLIMDSIQGECKVAQDQITTFNGVDLASALPENCYNVLAQDCSPEMKFMVLMRNSKESPNHKDINVKLGEYDIDMYYSADAFKMKINNLEVSEEHLPYKSFNYPTVEIKKKGNGVSLSASEYGIDSLDYDGLTFKFRPTIWMKGKTCGICGHNDDESEKELQMPDGSVAKDQMRFIHSWILPAESCSEGCNLKHTLVKLEKAIATDGAKAKCYSVQPVLRCAKGCSPVKTVEVSTGFHCLPSDVSLDLPEGQIRLEKSEDFSEKVEAHTACSCETSPCAA
What is the function of this protein?
Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.
What are the official names of this protein?
Vitellogenin-A2, VTG A2.