PharMolix/UniProtQA huggingface dataset:
Protein: FADN_BACSU
Sequence: MHKHIRKAAVLGSGVMGSGIAAHLANIGIPVLLLDIVPNDLTKEEEKKGLTKDSSEVRSRLSRQAMKKLLKQKPAPLTSAKNTSYITPGNLEDDAEKLKEADWIIEVVVENLEVKKKIFALVDEHRKTGSIVSSNTSGISVQEMAEGRSDDFKAHFLGTHFFNPARYLKLLEIIPIKETDPDILKFMTAFGENVLGKGVVTAKDTPNFIANRIGTYGLLVTVQEMLKGGYQVGEVDSITGPLIGRPKSATFRTLDVVGLDTFAHVARNVYDKADGDEKEVFRIPSFMNDMLEKGWIGSKAGQGFYKKEGKTIYELDPVTLTYGERTKMKSPALEAAKQAKGTKAKMKALIYSDDRAGRLLWNITSQTLLYSAELLGEIADDIHAIDQAMKWGFGWELGPFEMWDAIGLKQSAEKLEQLGADMPGWIKEMLDKGNETFYIKENGTVFYYDRGEYRAVKENKKRIHLQALKETKGVIAKNSGASLIDLGDDVALLEFHSKSNAIGLDIIQMIHKGLEETERNYKGLVIGNQGKNFCVGANLAMILMEVQDDNFLEVDFVIRRFQETMMKIKYSAKPVVAAPFGMTLGGGTEACLPAARIQAASEAYMGLVESGVGLIPGGGGNKELYINHLRRGHDPMNAAMKTFETIAMAKVSASAQEAREMNILKETDQISVNQDHLLYDAKQLAASLYDTGWRPPVKEKVKVPGETGYAALLLGAEQMKLSGYISEHDFKIAKKLAYVIAGGKVPFGTEVDEEYLLEIEREAFLSLSGEAKSQARMQHMLVKGKPLRN
What is the function of this protein?
Involved in the degradation of long-chain fatty acids.
What are the official names of this protein?
Probable 3-hydroxyacyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: CYB_CHIMC
Sequence: MTNIRKSHPLAKIVNSSFIDLPTPSSISSWWNFGSLLGVCLAVQILTGLFLAMHYTADTATAFNSVTHICRDVNYGWVLRYMHANGASMFFICLYLHVGRGLYYGSYTYTETWNVGIMLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISAMVMVHLLFLHETGSNNPTGIPSNMDMIPFHPYHTIKDILGLLLMLTMLLVLVMFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIIPLLHTSKQRSMMFRPISQCLFWLLVADMLTLTWIGGQPVEHPYIIIGQLASILYFSIILILMPLASLAENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CELA1_CANLF
Sequence: MLVLYGHSTQDVPETNARVVGGTEARRNSWPSQISLQYLSGGKWYHTCGGTLIRQNWVMTAAHCVDRTMTFRVVIGEHNLSQNDGTEQSASVQKIVVHPYWNSNDVSAGYDIALLRLAQKVTLNSYVQLGVLPQEGAILANNSPCYITGWGLTKTNGQLAQVLQQAYLPTVDYAICSSSSYWGSIVKKSMVCAGGDGIRSGCQGDSGGPLHCSVNGKYTVHGVTSFVSSLGCNVSRKPTVFTRVSAYITWINNVIASN
What is the function of this protein?
Acts upon elastin.
What are the official names of this protein?
Chymotrypsin-like elastase family member 1, Elastase-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KIN11_ARATH
Sequence: MDHSSNRFGNNGVESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPVKRITIPEIRQHRWFQTHLPRYLAVSPPDTVEQAKKINEEIVQEVVNMGFDRNQVLESLRNRTQNDATVTYYLLLDNRFRVPSGYLESEFQETTDSGSNPMRTPEAGASPVGHWIPAHVDHYGLGARSQVPVDRKWALGLQSHAHPREIMNEVLKALQELNVCWKKIGHYNMKCRWVPGLADGQNTMVNNQLHFRDESSIIEDDCAMTSPTVIKFELQLYKAREEKYLLDIQRVNGPQFLFLDLCAAFLTELRVI
What is the function of this protein?
Catalytic subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, a central regulator of cellular energy homeostasis, which, in response to seemingly unrelated darkness, sugar and stress conditions, activates energy-producing pathways and inhibits energy-consuming processes.  May play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants.  The SnRK complex may also be involved in the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase and in assimilation of nitrogen by phosphorylating nitrate reductase (PubMed:17671505).  In vitro, KIN11 exhibits kinase activity on sucrose phosphate synthase and the kinase activity is inhibited by PRL1 (PubMed:10220464).  May be a subunit of a SCF ubiquitin ligase complex and thus be involved in proteasomal ubiquitination (PubMed:11387208).  Involved in innate antiviral defenses (PubMed:12671096).  Phosphorylates REM4. 1 in vitro (PubMed:25289013).  Phosphorylates ADK2 in vitro (PubMed:24498147).
What are the official names of this protein?
SNF1-related protein kinase catalytic subunit alpha KIN11, AKIN11, AKIN alpha-1, AKINalpha1, SNF1-related kinase 1.2, SnRK1.2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Cytoplasm. Endoplasmic reticulum. Note=Co-localized with ER marker when associated with FLZ6 or FLZ10.
Protein: MTGA_ECOLI
Sequence: MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRSRQAWILRQMYQLGGEPFMQQHQLD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors (PubMed:6368264, PubMed:8772200, PubMed:18165305).  May play a role in peptidoglycan assembly during cell division in collaboration with other cell division proteins (PubMed:18165305).
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Monofunctional biosynthetic peptidoglycan transglycosylase, Monofunctional glycosyltransferase, Monofunctional GTase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=Localizes to the cell division site.
Protein: VSPCE_CERVI
Sequence: VIGGAKCNINEHRSIVLLYSSRLFGHTLINKEWVL
What is the function of this protein?
Thrombin-like snake venom serine protease, that cleaves both alpha-chain (FGA) and beta-chain (FGB) of fibrinogen.  Partially degrades factor X (F10), and release bradykinin from kininogen (KNG).  Potently induces platelet aggregation.  Shows a proteolytic activity towards protein constituents of the platelets cytoskeleton.  Hydrolyzes actin, actin-binding protein, and P235.  Shows a preferential cleavage at Arg-|-Xaa bonds.
What are the official names of this protein?
Thrombin-like enzyme cerastobin, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CRLS_MYCBO
Sequence: MEPVLTQNRVLTVPNMLSVIRLALIPAFVYVVLSAHANGWGVAILVFSGVSDWADGKIARLLNQSSRLGALLDPAVDRLYMVTVPIVFGLSGIVPWWFVLTLLTRDALLAGTLPLLWSRGLSALPVTYVGKAATFGFMVGFPTILLGQCDPLWSHVLLACGWAFLIWGMYAYLWAFVLYAVQMTMVVRQMPKLKGRAHRPAAQNAGERG
What is the function of this protein?
May catalyze the biosynthesis of cardiolipin from phosphatidylglycerol (PG) and CDP-diacylglycerol.
What are the official names of this protein?
Putative cardiolipin synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COX2_MERSH
Sequence: MAYPLQLGLQDASSPIMEELTNFHDHTLMIVFLISSLVLYLISLMLTTKLIHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMTPTNELKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGVFYGQCSEICGSNHSFMPIVLEMIPLKLFENWSVSMTQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SRP54_HALSA
Sequence: MVLDDLGSSLRGTLDTLRGKSRISEEDVDKVVKEIQRSLLQADVDVDLVMDLSESITERSLEEEPPGGTSARDHVLRIVYEELVGLVGDSTPIPLEEQTIMLAGLQGSGKTTTAAKMAWWFSKKGLRPAIVQTDTFRPGAYEQAAEMADRAEVDFYGEPDSDDPVQIARDGLAATADADVHIVDTAGRHALEDDLIAEIEEIEGVVEPDRSLLVLDAAIGQGAKQQARQFDASIGIDGVAITKLDGTAKGGGSLTAVNETDSTIAFLGSGETVQDIERFEPDSFISRLLGMGDLKQLTERVERAMEETQDDDEDWDPEDLMKGEFTLHDMRKQMQAMDNMGPLDQVMDMIPGMGGGLMDELPDDAMDVTQERMRGFEVIMDSMTEAEMADPRSVGASQIRRIARGSGQPEDRVRELLDQHKMMAQTMQQFQGMGDGDMQRMMSKMQQQGGGGGGGFGGMF
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: MALR_CLOBU
Sequence: MNIKDIARLSGVGVSTVSRVINNHPDVKQSTREKVLQIIKDSNYIPNNSARILKQNNTKNIGVLVKGVFNPFFSEMTNIIGNIIEENGYTMILQQNDFNLYQDVETMIGFVKEKRLQGVICLGGNFTEIQEDSFEDIKVPVVLTSVNTISKKGKKYYSSVGIDNSKSAYKAVRYLIERVIKDCFGLGEVNDLGVSWWRLDGYKKALGENNIDIDDELIISGEYNSGTAYENVNKLLKKRKDITAIFALSDIMALGAIKAAIDNGLDVPRDISIVGFDGMDESKYYNPSITTVKQPKKKMAETSVELLFSLITTDGENKHVILDTELVERDSCFNI
What is the function of this protein?
Repressor of glucanotransferase gene expression.
What are the official names of this protein?
HTH-type transcriptional regulator MalR.
Protein: FWCH2_PONAB
Sequence: MPLPEPSEQEGESVKAGQEPSSKPGTEVVPAAPRKPREFSKLVLLTASKDSTKVAGAKRKGVHCVMSLGVPGPATLAKALLQTHPEAQRAIEAAPQEPEQKRSRQDPGADRTEDSGLAAGPPEAAGENSAPCSVAPGKSL
What are the official names of this protein?
FLYWCH family member 2.
Protein: ACPH_MOUSE
Sequence: MERQVLLSEPQEAAALYRGLSRQPSLSAACLGPEVTTQYGGLYRTVHTEWTQRDLDRMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGAVSGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVSASDEEMARPKKPDQAIKGDQFVFYEDWGETMVSKSIPVLCVLDIESGNISVLEGVPENVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRYCTNRRSALYYVDLSGGKCELLSDESLAVCSPRLSPDQCRVVYLQYPSLAPHHQCSQLFLYDWYTKVTSLVVDIVPRQLGESFSGIYCSLLPLGCWSADSQRVVFDSVQRSRQDLFAVDTQTGSVTSLTAGGSAGSWKLLTIDRDLMVAQFSTPNLPPSLKVGFLPPAGKEQSVSWVSLEEAEPIPDIHWGIRVLHPPPDQENVQYADLDFEAILLQPSNSPDKSQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVQQVLQEEHFDARRVALMGGSHGGFLSCHLIGQYPETYSACIARNPVINIVSMMGTTDIPDWCMVETGFPYSNDYLPDLNVLEEMLDKSPIKYIPQVKTPVLLMLGQEDRRVPFKQGLEYYHALKARNVPVRLLLYPKSTHALSEVEVESDSFMNTVLWLHTHLGS
What is the function of this protein?
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus (By similarity).  It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser (By similarity).  Also, involved in the degradation of oxidized and glycated proteins (By similarity).
What are the official names of this protein?
Acylamino-acid-releasing enzyme, AARE, Acyl-peptide hydrolase, APH, Acylaminoacyl-peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
Protein: RL22_HAEIG
Sequence: METIAKHRYARTSAQKARLVADLIRGKKVAQALEILTFTNKKAAALVKKVLESAIANAEHNDGADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PPIB_GIBZE
Sequence: MFNLRRLFASALFLGLGLLFLAQTAEAAKGPKITHKVYFDITQGDQPLGRVVMGLYGKTVPETTENFRALATGEKGFGYEGSAFHRVIKNFMIQGGDFTKGDGTGGKSIYGDRFKDENFKLKHTKKGLLSMANAGRDTNGSQFFITTVVTSWLDGKHVVFGEVLEGYEIIEKIENSKTGAADRPVEAVKIAKSGELDVPPEGLVGTSEFAAEEVASAGWSPMQKAGLFAIFAGVLFVGLRSARQHSRF
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B, PPIase B, Rotamase B.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
[Isoform Long]: Membrane; Single- pass membrane protein. SUBCELLULAR LOCATION: [Isoform Short]: Endoplasmic reticulum lumen.
Protein: CDK8_MOUSE
Sequence: MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLLKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDEKGDKKTQQQQQGNNHTNGTGHPGNQDSGHAQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.  Phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.  Phosphorylates CCNH leading to down-regulation of the TFIIH complex and transcriptional repression.  Recruited through interaction with MAML1 to hyperphosphorylate the intracellular domain of NOTCH, leading to its degradation (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 8, Cell division protein kinase 8, Mediator complex subunit CDK8, Mediator of RNA polymerase II transcription subunit CDK8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NOX4_PONAB
Sequence: MAVSWRSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGLTGVCMVVVLFLMITASTYAIRVSNYDIFWYTHNLFFVFYMLLTLHVSGGLLKYQTNLDTHPPGCISLNRTSSQNISLPEYFSEHFHEPFPEGFSKPEEFTQNTFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLYRYIRSNKPVTIISVISHPSDVMEIRMVKENFKARPGQYITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQENRPDYVNIQLYLSQTDGIQKIIGEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQINSYGTRFEYNKESFS
What is the function of this protein?
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox.  Regulates signaling cascades probably through phosphatases inhibition.  May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity.  May regulate insulin signaling cascade.  May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB (By similarity).
What are the official names of this protein?
NADPH oxidase 4.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, focal adhesion. Cell membrane. Note=May localize to plasma membrane and focal adhesions.
Protein: RSMF_ECO7I
Sequence: MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEAVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPVLPAPKYKVGNFPFSPVKDREAGQIRQAAAGVGLNWDGNLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTGNA
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIXI_ORTSC
Sequence: DGYPKQKDGCKYSCTINHKFCNSVCKSNGGDYGYCWFWGLACWCEGLPDNKMWKYETNTCGGKK
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  This toxin is active only on insects.
What are the official names of this protein?
Insect toxin OsI1, Insecticidal toxin OsI-1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VIOA_ECOLX
Sequence: MNDKTIPVTQPSLPELAEFMPYLEKIWKNKWLTNNGPFHQELEEKLCEFLGVQHISLFNNATIALITALQALRITGEVITTPYSFVATSHAILWNGLTPVFVDIENDGYNIDYRKIEQAITPKTSAILPVHCYSTPCEVEEIQKIADNYGLKVIYDAAHAFGVNFKGGKVYLTMVIYQFLVSMRRKSSINFEGGAIISPDAKTKLRIDRLKNFGIADELTVTAPGINGKMSEINAAFGLVQLKHIEGSISKRKIIDSLYRNLLKGTPGITIFPGNINTNSNYSYFPILIDDGFHMSRDQAYELLKKNNILSRKYFYPLISNMPMYRGLISASVDNLPIANSVADKVLCLPIYTDLNEEIVVKITKLLLGKM
What is the function of this protein?
Catalyzes the conversion of dTDP-4-dehydro-6-deoxy-D-glucose (dTDP-D-Glc4O) to dTDP-4-amino-4,6-dideoxy-D-glucose (dTDP-D-Qui4N).
What are the official names of this protein?
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family.
Protein: GADL1_XENTR
Sequence: HDIDKNKQETRPMKRNAVLVDGVVLNGPIIDSSSGEKFVEDVYRILMNELVYKASDINQKVCEWQEPEQLKKLLDLNIKDNGEPHEKLLQLCKNVIKYSVKTSHPRFFNQLYAGMDHYSLAARFITEALNPSVYTYEVSPVFILTEEAILKKMIEFLGWKEGDGIFSPGGSVSNMYAVNLARYKYCPDIKQKGLSSAPRLVMFTSEECHYSMKKAAAFLGIGTENVYFVKTDDRGKMIPEELENQIQRAKKEGAVPFLVSATSGTTVLGAFDPLDDIANICEKHKLWFHVDASWGGSALMSQKYRKRLHGIHRADSVAWNPHKMLMAGIQCCALLVRDNSGLLKRCHSAEATYLFQQDKFYDVQYDTGDKSIQCSRRADAFKFWMMWKALGTTGLEERINRALALTRYLASEIKKRDGFELLWEPEYANTCFWYIPPSFRNMEKGPEYWRKFSNVAPTIKERMMKKGSMMVGYQPHRDKVNFFRHIVISPQVSREDMDFVLDEIERLGRDL
What is the function of this protein?
Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively.  The preferred substrate is L-aspartate.  Does not exhibit any decarboxylation activity toward glutamate.
What are the official names of this protein?
Acidic amino acid decarboxylase GADL1, Aspartate 1-decarboxylase, ADC, Cysteine sulfinic acid decarboxylase, CSADC, Glutamate decarboxylase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: HEM1_COXBR
Sequence: MPLLVCGINHQSAPLTVREKLVFTPERTPLALQSLLAEKAVNEALLLSTCNRTEIYTTVDEAATILRWLSKQPQLSGIDLRSFCYARRDIEMVRHVMRVGSGLDSMVLGEPQILGQMKQAYLLARRIGAVGSELGRLFPAVFAATKRIRSETAIGANPVSIAYAVVQLAKRIFSHLNQCQILLIGAGETIELVFSHLYNQGARHFFIANRTLTRAKQIAEPYHAQAIRLSDIPTYLPKVDIVISATMSQLPLVGKGAVESALRQRKRRPLFMADLALPRDIEPETAQLEDVYLYNIDDLQTLIAQNRQTREAAAKQAEAMVEMQAIHYMRQLQVHKAGDTIRRFRERVEMLRDQELEKALAHFQRTNDPKAVIAHFAHNLTNKILHQPTTKLRQAAYEDQVQLLLSAKELFDL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CUEO_YERPE
Sequence: MHRRDFLKLTAALGAATSLPLWSRAALAADFSPLPIPPLLQPDANGKINLNIQTGSVVWLPSTATQTWGYNGNLLGPAIRLQRGKAVTIDITNALPEATTVHWHGLEIPGEVDGGPQALIQPGAKRQVTFAVEQPAATCWFHPHTHSKTGHQVAMGLGGLVLIDDSDSETLPLPKQWGVDDIPVILQDKLLDKHGQVDYQLDVMTAAVGWFGDRMLTNGVPYPQQITPRGWVRLRLLNGCNARSLNLALSDGRPMYVIASDGGLLAEPVVVRELPILMGERFEVLVDTRDGQSLDLVTLPVTQMGMTLAPFDQPLPVLRIQPSLAIGSQVLPESLVVIPELADVTGVQERWFQLMMDPKLDMLGMQALVARYGMKAMAGMNMNHGDMGAMDHGNRPDMSQGKMKGMDHGTMNGAPAFNFSHANRINGKAFSMTEPAFDAKQGKYEKWTISGEGDMMLHPFHVHGTQFRILTENGKPPAEHRRGWKDIVRVEGARSEILVRFNYLAPASTPYMAHCHLLEHEDTGMMLGFTVSA
What is the function of this protein?
Multicopper oxidase involved in copper homeostasis and copper tolerance under aerobic conditions.  Is responsible for the oxidation of Cu(+) to the less harmful Cu(2+) in the periplasm, thereby preventing Cu(+) from entering the cytoplasm.
What are the official names of this protein?
Multicopper oxidase CueO, MCO, Copper efflux oxidase, Cu efflux oxidase, Cuprous oxidase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RUTB_SERP5
Sequence: MKIVENQPVVRRQSPQAEVTLTLPARPEAIAFAPQETALIVVDMQNAYASQGGYLDLAGFDISATAPVIANIKRAISAARAAGIKVIFFQNGWDNQYVEAGGQGSPNWHKSNALKTMRKRPELMGKLLARGDWDYDLVDELQPQAGDIVLPKPRYSGFFNTQLDSLLRSYGIHHLVFTGIATNVCVESTLRDGFFLEYFGIVLADATHQAGPQFAQQAALYNIETFFGWVSDVDSFCNTLAAPLSQTA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.