PharMolix/UniProtQA huggingface dataset:
Protein: CADC_ALKPO
Sequence: MNKKDTCEIFCYDEEKVNRIQGDLKTIDIVSVAQMLKAIADENRAKITYALCQDEELCVCDIANIIGITVANASHHLRTLHKQGIVRYRKEGKLAFYSLDDEHIRQIMMIVLEHKKEVNVNV
What is the function of this protein?
Metal-binding repressor for the cad operon.  Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead.  Metal binding causes the repressor to dissociate from the DNA (By similarity).
What are the official names of this protein?
Cadmium resistance transcriptional regulatory protein CadC, Cadmium efflux system accessory protein.
Protein: METK_GEOSM
Sequence: MEMKDFIFTSESVSEGHPDKVADQVSDAILDAILTQDPKSRVACETMVTTGMAVIAGEITTNAIIDYPKIVRETIREIGYNDSAMGFDWETCAVLTSIDKQSPDIAQGVTEGEGMFKEQGAGDQGLMFGFACNETPELMPMSILLAHKLVSRLADVRKAGVLDFLRPDSKSQVSIQYIDDKPVHVDTVVISSQHSPEVSYEMIKEGIIEEVVKKIIPANLMDSKTKFLINPTGRFVIGGPMGDCGLTGRKIIVDSYGGHGAHGGGAFSGKDPSKVDRSAAYMGRYVAKNLVASGVCERCEVQVAYAIGVAEPVSVMVDCNGTGKIPSKRISEIVREVFDMRPRAIIEQLDLLRPIYRKTAAYGHFGRELPEFTWERTDKAAIIREKAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPM8_MOUSE
Sequence: MSFEGARLSMRSRRNGTMGSTRTLYSSVSRSTDVSYSDSDLVNFIQANFKKRECVFFTRDSKAMENICKCGYAQSQHIEGTQINQNEKWNYKKHTKEFPTDAFGDIQFETLGKKGKYLRLSCDTDSETLYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRNSEENIVAIGIAAWGMVSNRDTLIRSCDDEGHFSAQYIMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKAINTSVKSKIPCVVVEGSGQIADVIASLVEVEDVLTSSMVKEKLVRFLPRTVSRLPEEEIESWIKWLKEILESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQDKDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALLTFVWKLVANFRRSFWKEDRSSREDLDVELHDASLTTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPLVGCGLVSFRKKPIDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQEYCNRLNIPFPFVVFAYFYMVVKKCFKCCCKEKNMESNACCFRNEDNETLAWEGVMKENYLVKINTKANDNSEEMRHRFRQLDSKLNDLKSLLKEIANNIK
What is the function of this protein?
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius.  Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH.  Involved in menthol sensation.  Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.  Temperature sensing is tightly linked to voltage-dependent gating.  Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves.  The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials.  Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member 8, Long transient receptor potential channel 6, LTrpC-6, LTrpC6, Transient receptor potential p8, Trp-p8.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM8 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft. Note=Localizes to membrane rafts but is also located in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts.
Protein: GAL1_CLOPE
Sequence: MELNTLKSTFINNFGKEPNSLFFSPGRINLIGEHIDYNGGFVFPCPITLGTFAAASLRDDRICRAYSLNFESLGVIEFSLDDLSYKKEDNWTNYLKGVLKVLIEKGYKIDKGIDLVINGNLPNGAGLSSSASLEMLIVKILDTFFSLNISKVDAALIGKEVENTYIGVNSGIMDQFAISLGEKDKAILLDCNSLYYEYVPLNLGDNSIIIMNTNKRRELADSKYNERRKECDDSLDTLKKYTNISSLCELTSLEFETYKDKIEDSNKLRRCVHAISENERVKDAVKALKENNLELFGQLMNQSHISLRDDYEVTGKELDTLAENAWKQPGVLGARMTGAGFGGCAIAIVNNAHVDEFIKNVGQAYKDAIGYEASFYVASIGNGPTEL
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_CHLT3
Sequence: MSKVCILTGKKHQYGNTVSHANNHRRTRFEPNIQAKRIWLEEEKRWVKVKLSAKAIKIISKRGTAELAKLLQGK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: H2A_TIGCA
Sequence: MSGRGKGGKVKGKAKSRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ALX_SALTI
Sequence: MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGWSILWVTLSLLFNAAFWWYLAETQGREVADPQALAFLTGYLIEKSLAVDNVFVWLMLFSYFSVPPALQRRVLVYGVLGAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMALAKEDESGIGEKPMVRWLRGHLRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVIFAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAISLGVVFGILTITLVINTWVNHQRDKKLRAQ
What is the function of this protein?
Has been proposed to be a redox modulator.
What are the official names of this protein?
Putative membrane-bound redox modulator Alx.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2628_MYCBO
Sequence: MGNLLVVIAVALFIAAIVVLVVAIRRPKTPATPGGRRDPLAFDAMPQFGPRQLGPGAIVSHGGIDYVVRGSVTFREGPFVWWEHLLEGGDTPTWLSVQEDDGRLELAMWVKRTDLGLQPGGQHVIDGVTFQETERGHAGYTTEGTTGLPAGGEMDYVDCASAGQGADESMLLSFERWAPDMGWEIATGKSVLAGELTVYPAPPVSA
What are the official names of this protein?
Uncharacterized protein Mb2628.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NDD_BPR69
Sequence: MKYMTVTDLNNAGATVIGTIKGGEWFLGTPHKDILSKPGFYFLVSKLDGRPFSNPCVSARFYVGNQRSKQGFSAVLSHIRQRRSQLARTIANNNMVYTVFYLPASKMKPLTTGFGKGQLALAFTRNHHSEYQTLEEMNRMLADNFKFVLQAY
What is the function of this protein?
Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation.  Only the architecture of the nucleoid is affected.  May act on the host chromosomal sequences that determine the structure of the nucleoid.  Binds to dsDNA but not to ssDNA.
What are the official names of this protein?
Nucleoid disruption protein, Nuclear disruption protein.
Protein: RLMH_BACC4
Sequence: MNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_AGRFC
Sequence: METDGKTLRRGWTTGTCAAAATKAACAALLTGEFPYPVDVELPSGARPAFSLATEEKGENFARAGVVKDAGDDPDVTHGALIESTVRRGEPGSGITFRAGKGVGIITRPGLPLPPGEPAINPVPRRMIETAIREVAGENADFEVEISVRDGEKLAEKTLNGRLGILGGISILGTTGVVIPFSCSAWIHSIWRGIDVARATGCTHVLGATGNTSEKAGQAVYDLPETALIDMGDFIGGMLKYLRSHPVERVTIAGGVAKMTKLAQGMLDVHSKKGLADLEALAVLAAEAGGDDNLAVAIRQANMVAHAFQLAESVGIDLGAVVAEKAWVTAAAALKTPAIALDILVFDRQGALKGRTTSTPSHQPAPSSFGDRNRRT
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: FB103_ARATH
Sequence: METPNPLTLSELPHDLLRNIFNRLSFADFHRATWNSISKQTAPPKTKSPWLILFPDEGVHGCVLYNPDEDRIYKSVRDFSGTIFLANSGNWFLVMDSKSNLYIIDVFSENRIDLPPLESLLSDNFTFEQKGDKELKWQASNDQILVFRLPRAEELRGILWVDEKMKEFVAVWFLEDSCNFLAFYKKADDHYSHIQLEYVITDVFQSVSDIVLHGCFLYIGVGDYIQIIDLSKDQGFKDVTRNYLFNVHNGPWGFRSIFNLVVTTSGEVLMVLNNLYEKNIESEKSFRIFKKDPNPDPNKHDNLLVEVDSLGNEEVMLLDLGITMHGIEPNSIYFTRHDRVVHRLYIS
What are the official names of this protein?
F-box protein At2g14500.
Protein: RL32_RHOPA
Sequence: MAVPRRKTSPSRRGMRRSADAIKRPTYVEDKDSGELRRPHHLDLKTGMYKGRQVLKKKDS
What are the official names of this protein?
50S ribosomal protein L32, RRP-L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: PSBF_SPIOL
Sequence: MTIDRTYPIFTVRWLAIHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: IF5A_SULIY
Sequence: MSITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAPVDQQVEVPIIEKHIGQIIADMGDKIQVMDLETYETFEIEKPTEDELASKIRPNAELEYWEIMGRRKIVRVK
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPA1_HUMAN
Sequence: MLLKKHAGKGGGREPRSEDPTPAEQHCARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPGLDGLDAPCQLGPDGLPMPGCWQK
What is the function of this protein?
Inhibits fibrillization of amyloid-beta peptide during the elongation phase.  Has also been shown to assemble amyloid fibrils into protease-resistant aggregates.  Binds heparin.
What are the official names of this protein?
Collagen alpha-1(XXV) chain, Alzheimer disease amyloid-associated protein, AMY, CLAC-P.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Note=After proteolytic cleavage, CLAC is secreted.
Protein: YCF42_TRICV
Sequence: MTNFPKIGKTPPNFLTIGVYKKRLGKIRLSDYRGKKYVILFFYPANFTAISPTELMLLSDRISEFRKLSTQILAISVDSPFSHLQYLLCNREEGGLEDLNYPLVSDLTQTITRDYQVLTDEGLAFPGLFIIDKEGIIQYYTVNNLLCGRNINELLRILESIQYVKENPGYACPVNWNFGDQVFYSHPLKSKIYFKDLYSPKKSS
What are the official names of this protein?
Putative peroxiredoxin ycf42, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ORC6_MOUSE
Sequence: MESELVRRLAPRLGLAEPSVLRKAEEFLRLSKVKCVSLSARSSETSNAVICLDLAASCRKCPLDRAYLIRLSGLNKMMYQSCLKSFECLLGLNSNVGIRDLAVQFSCTEAVNLAAEILQSYKSGLPETQRADLDLSRPLFTTAALLSACKILKIKVDKTKMITTSGVKKAILDRLCKQLEKIGQQINRDSADLARPALKRKKPEFSPTLKKKEPGLEPPAKEIEVIETLHKLPKDEDLTQDYEEWKRKILENAAKAQTATAE
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ORC6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CBPA3_MOUSE
Sequence: MRFFLLMAVIYTTLAIAPVHFDREKVFRVKLQNEKHASVLKNLTQSIELDFWYPDAIHDIAVNMTVDFRVSEKESQTIQSTLEQHKIHYEILIHDLQEEIEKQFDVKDEIAGRHSYAKYNDWDKIVSWTEKMLEKHPEMVSRIKIGSTVEDNPLYVLKIGKKDGERKAIFMDCGIHAREWISPAFCQWFVYQATKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQDRMWRKNRSRNQNSTCIGTDLNRNFDVSWDSSPNTNKPCLNVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLIPYGYTFKLPPNHQDLLKVARIATDALSTRYETRYIYGPIASTIYKTSGSSLDWVYDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKNTS
What are the official names of this protein?
Mast cell carboxypeptidase A, MC-CPA, Carboxypeptidase A3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Protein: SKI3_YEAST
Sequence: MSDIKQLLKEAKQELTNRDYEETIEISEKVLKLDPDNYFAHIFLGKALSSLPASNNVSSNRNLERATNHYVSAAKLVPDNLLAWKGLFLLFRTTEVVPDILSYDEYFDLCGQYADALLKQEQSQVELINDIKLLKKTHPDCQKAFYQHLKPGSLMAETIGRHLSTPQDALLNLIKILSNIETTEIGKTLSQNRLKLKASDPDYQIKLNSFSWEIIKNSEIDQLYNQLVNILADDQKRSEIENQWLEYRIKVLKSMPLDVKKDFFTKVKEMVEDMVLVNHQSLLAWQKYFEWTDYEDLDNMDAPLIIKYFKKFPKDPLAMILYSWLSSKLSKYDIKSLESANKPPEGHKKTEKETDIKDVDETNEDEVKDRVEDEVKDRVEDEVKDQDEEAKEDEEEDLDDIEIGLLEEEVVTVLTENIVKCKNNILAHRILCQYYLLTKEYEAALPYIKNGISLIAYNIKDLGVHLPLTKREFSLDLATVYTYVDAPKDHNAALKLYDNILSGDFSNIQAKMGKGIIFIERKNWKDAMTLLTQVHEQSPNNLEVLSELSWSKAHMGYMDEALAGLDTVIKGIKGMDLRSIDFRALNLWRQAKVYIMKHASINDAKQENVKCAFKLLIQSIKILDTFAPGFSTLGDIYCHYYKDHLRAFKCYFKAFDLDAGDYTAAKYITETYASKPNWQAASSIASRLIKGEKAKAELRSNNWPFRVVGIAHLEKQEESDSIEWFQSALRVDPNDVESWVGLGQAYHACGRIEASIKVFDKAIQLRPSHTFAQYFKAISLCDVGEYLESLDILEKVCQEAATEESFQIGLVEVLMRCSLDLYSQGFLLKSVSIAKDTIERIKIIISELKCENQQVWIYLSQVLRLFIWIESKVDTLPVESLVSIFENSQFSGSEEIDSVDNIKIDTLLDSTTDDNVSIACKFLILASKYSVSDQKFTDIAGTVRASYWYNIGISELTAFITLKEPQYRDAAIFAFKKSIQLQSNTSETWIGLGIATMDINFRVSQHCFIKATALEPKATNTWFNLAMLGLKKKDTEFAQQVLNKLQSLAPQDSSPWLGMALILEEQGDIIGSSKLFAHSFILSNGRSKAAQFMYAKNVLENHINNGDDERDIETVEKLTTASIALEQFFKKSPDSQFALQCALLTLERLHHYENANELANRLIGILEKKFEKTQDERELFNFAIIKGQFARIHLGLGNFELSIENADLSQGIISESSDEKSMKTKISNHICLGLSYFFLNDFDQTLNQFQELLSISKDSKHLVVLIAKVLYDVGESDTKEIALQELTEYIATSGADLLVTLTIAAMSILDDKREDLSIILEELKALPLSKQIIDKHKDAPYLIEEITKRLYRNDTGKQVWQRSAYFFPNNLKVWERLDKNIQRRIASNGQNKVTAEEMSKLYCESKNLRSIQRGMFLCPWNVTAVKALNECF
What is the function of this protein?
Component of the SKI complex involved in 3'-mRNA degradation pathway.  Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A).  Essential for cell growth only in the presence of M1 replicon.
What are the official names of this protein?
Superkiller protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FADJ_SHEB8
Sequence: MEKTFNLTRRDDGIAILTMDVPGETMNTLKAQFGPEISEILAEIKSDSSIRGLVLISGKKDSFVAGADISMLDACKTAGDAKALSQQGHVVFNELEALTIPVVAAIHGACLGGGLELALACHQRVCSDDGKTMLGVPEVQLGLLPGGGGTQRLPRLVGITTALDMMLTGKKIRPKQALKMGLVNDVVPQTILLQTAVEMALAGKRAPKPVKKSLVNQVLEGTSFGRNIIFDQATKQVEKKTQGNYPAPAKIIDCVRQGIAKGMQKGLEVEASHFAELVVSKESEALRSIFFATTEMKKETGAEGASPRKVKKAVILGGGLMGGGIASVTTTKAKIPVRVKDISEKGLSNALAYAYKLLDKGVKRRHMTPAARDNLMALMTTTTEYKGVKDADIVVEAVFEDLALKHQMVKDIERECGEHTIFASNTSSLPISQIAEAATRPENVIGLHYFSPVEKMPLVEVIAHAKTSPETIATTVAFARKQGKTPIVVQDGAGFYVNRILALYMNEAAQLLLEGQSVEHLDKALVKFGFPVGPITLLDEVGIDVGAKISPILEKELGERFKAPAAFDKLLSDDRKGRKNGKGFYQYGASSKKAKAVDESVYGVLGIKPGTNKDAKAVAERCVVQMLNEAVRCLEDGIIASPRDGDIGAIFGIGFPPFLGGPFHYIDTLGAANLVKILESYQSQFGNRFEPCERLKTMAQENAHFF
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REF2P_DROSI
Sequence: MPEKLLKITYQGAGPQKKINAYLRMPSQNYTILRREIELYLFQERQLPKCDVRTFWIDADQDEIEIVNQNDYEIFLAKCESNMHVQVAPLAPIEEPKATKQEGSSANAEAPSVDDPSNFTIHDSVQCDGCGLAPLIGFRYKCVQCSNFDLCQKCESAHKHPEHLMLRMPTNNGPGMVDAWFTGPGLGRRCGRRSRGHCPFQEASQPAPAAEPARDSRRERRHARRHAGVLSQFVEMMTNLPLNTTTATAPAEPQKPKAAEQTESPPQAEPTVTAEKATESEAKPTEPMKVNTDQSVPTTEDPVTTPRSTEPTTPVINLDNLSQIVPPEYMRAGIEILNNFSEMFSKMIDTTDVGDSGIFAPSTTSSAENKKPEEQSQSSGQSAASSASQSAVPSAAPSANQSNVPSANQSATPSISGSISDAQLETEPLNPKPLETTTETEQDRRRSDSLDPEWQLIDNAYSANNSNLINLDTTNPTAAPQQPVRDFGQLGELLRQHMNEEARVEQASANTQTAQVDTVSTSTSTTSVTTNSVGTSPAAPDDKRTVPVYHTDERINQSIHAMMAMGFSNEGAWLTQLLESVQGNIPAALDVMHVSQTRN
What is the function of this protein?
Required for selective autophagy activation by ubiquitinated proteins.  Implicated in sigma rhabdovirus multiplication and necessary for male fertility.  Involved in activating transcription of Drs.
What are the official names of this protein?
Protein ref(2)P, Refractory to sigma P.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ATPD_LACAC
Sequence: MALSREEVAARYGTALFGYAQDNKVLDTVYDEMMALKKAAIANPKFISVLSDPILSSKDKKSILTAVEKDFSDEVQGFLNLLLEYNRFADLIDIIDQFSLLYDNENKIASGTATTAVKLDDDQLERLSESFAKKYDLNAVRLENKVDPSILGGVILQVKDRVIDGSVKNKLKKIRAQIIDEN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TDRD5_BOVIN
Sequence: MSEQERIQECLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIANLVAKQKSNHKVRNSMQKGRASVCSGPSSRRRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFENAFANRFGRSFQYVQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEEKQRGWPAAKGKIFTQPFRMKQQGSYPIGFPVAKACFSQPTSNMEPPKQILGMERNSRSNVMETSRLNHSEKLNQLALTLQSWVVSHYGFNGSFSSAKKHKAMYTLRKFTENLMVCCLFNEYMLIFKEQLSPKKLGFLNVIELVGALSDILHVEFREGEQDLLVFDADMKPLASVQPDKKTEAKACVSSPPRNSLSTAVIKETTWDCPSKNHKEPEQKIFKKPNLVVKPLQLQVEINKSQLSLAVANHDIPPDAVRDKKLCRLPPLDTSTLVGVFVEYILSPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYAMPECFIQPGHLCCVRISEDKWWYRVIIHRILGKQEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSRAVLQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENVPSKGFRDLNPLALYTKSSVTPEDIVLKELGYHSQQHYFNEDREISPQSKESDLYTLDEIPTGMPYLESVTIGDDIWDENWLPLQAKMGKESDAASHLFTSSLGGKKPYPSCKEIPQKDWCFSTPKDIWDDSWQPSGLVNGMKVEVQIPEGLGAQEKHIDTTRIQKQSNVKSASDSPALPKLEEFYISLIQSQQSAEGSQFEPSNIQTPPKQIQLSSTPTLVNSGSVEGSPESLENEDFSSSSAITVFKDTSQGAVDQLSLILSPEHQISQKFYIPRSTATAALGAAARLATSNSLLHWYPSVKKMET
What is the function of this protein?
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity.  Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Required for chromatoid body (CB) assembly (By similarity).
What are the official names of this protein?
Tudor domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the TDRD5 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.
Protein: TRMA_ACIBY
Sequence: MTSSYRQQLQAKIDRITTQFSEFTPPTLEVFESPEQHFRMRAEFRIWHTENDMFYAMFERNGDGKQKTVVRIDEFPIADKSINDLMPLLLAELKANSLLSQRLFEVDFLATLSGEMLVTLIYHRKLNQEWEQAAKALAEKLNIKIMGRSRGQKIVIGDDFVVEEFELLNRSFKYKQIESSFTQPNAQVCKKMLQWACDAAEGSKKHLLELYCGNGNFTLPLSLKFERVLATELAKSSVYAAQWNIEQNQIDNIQVARLSAEEFTQAYQGEREFRRLQEADIDIQSYDFGTVFVDPPRAGIDDETLKLLQGFERIIYISCNPDTLYENLKTLTQTHRVTKFALFDQFPYTHHVESGVLLEKI
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: MAO1_PHOLL
Sequence: MELEHESKRPLYIPYSGPILLEFPLLNKGSAFTEEERRNFNLHGLLPEAVETIEEQAERAYRQYLDFKNDADKHIYLRNIQDTNETLFYRLLDAHLNEMMPIIYTPTVGEACEHFSDIYRRARGLFISHPNKAHIDDMLQNATKQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTSCGGISPAYTLPVVLDVGTNNPQRLNDPLYMGWRHPRITGKEYDEFVDEFIQAVKRRWPNVLLQFEDFAQKNAMPLLNRYRHEICCFNDDIQGTAAVTLGSLIAASRAAGRQLKDQTVTFLGAGSAGCGIAEQIVAQMKSEGLSDEQARARIFMVDRFGLLTDKLPNLLDFQNKLVQKSSSLAKWDVNNDSISLLDVVRNAKPTVLIGVSGQAGLFTEEIIREMHKHCERPIVMPLSNPTSRVEARPEDIINWTDGAALVATGSPFNPVKYKDQEYPIAQCNNAYIFPGIGLGVIASGAKLVTDGMLMAASRTLANCSPLAQEGQGPLLPLIDDIQEVSRKIAKQVAKEAQIQGVATVTSDGALDEAIERNFWKPEYRVYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.