PharMolix/UniProtQA huggingface dataset:
Protein: SPT4_CRYNJ
Sequence: MPPKSGRAELRACLVCSILQSTNDFLTQGCPNCEDILEMRGSAERVAECTSLLYDGMIAMIEPSESWVARWQRIDKRMRGIYAVRVTGRAPQDVIDAIEARGGVYRPRDAVED
What is the function of this protein?
The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4, Chromatin elongation factor SPT4.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Centromere and heterochromatin.
Protein: HAP1_YEAST
Sequence: MSNTPYNSSVPSIASMTQSSVSRSPNMHTATTPGANTSSNSPPLHMSSDSSKIKRKRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELKKLRERVKSLEKTLSKVHSSPSSNSLKSYNTPESSNLFMGSDEHTTLVNANTGSASSASHMHQQQQQQQQQEQQQDFSRSANANANSSSLSISNKYDNDELDLTKDFDLLHIKSNGTIHLGATHWLSIMKGDPYLKLLWGHIFAMREKLNEWYYQKNSYSKLKSSKCPINHAQAPPSAAAAATRKCPVDHSAFSSGMVAPKEETPLPRKCPVDHTMFSSGMIPPREDTSSQKRCPVDHTMYSAGMMPPKDETPSPFSTKAMIDHNKHTMNPPQSKCPVDHRNYMKDYPSDMANSSSNPASRCPIDHSSMKNTAALPASTHNTIPHHQPQSGSHARSHPAQSRKHDSYMTESEVLATLCEMLPPKRVIALFIEKFFKHLYPAIPILDEQNFKNHVNQMLSLSSMNPTVNNFGMSMPSSSTLENQPITQINLPKLSDSCNLGILIIILRLTWLSIPSNSCEVDLGEESGSFLVPNESSNMSASALTSMAKEESLLLKHETPVEALELCQKYLIKFDELSSISNNNVNLTTVQFAIFYNFYMKSASNDLTTLTNTNNTGMANPGHDSESHQILLSNITQMAFSCGLHRDPDNFPQLNATIPATSQDVSNNGSKKANPSTNPTLNNNMSAATTNSSSRSGSADSRSGSNPVNKKENQVSIERFKHTWRKIWYYIVSMDVNQSLSLGSPRLLRNLRDFSDTKLPSASRIDYVRDIKELIIVKNFTLFFQIDLCIIAVLNHILNVSLARSVRKFELDSLINLLKNLTYGTENVNDVVSSLINKGLLPTSEGGSVDSNNDEIYGLPKLPDILNHGQHNQNLYADGRNTSSSDIDKKLDLPHESTTRALFFSKHMTIRMLLYLLNYILFTHYEPMGSEDPGTNILAKEYAQEALNFAMDGYRNCMIFFNNIRNTNSLFDYMNVILSYPCLDIGHRSLQFIVCLILRAKCGPLTGMRESSIITNGTSSGFNSSVEDEDVKVKQESSDELKKDDFMKDVNLDSGDSLAEILMSRMLLFQKLTKQLSKKYNYAIRMNKSTGFFVSLLDTPSKKSDSKSGGSSFMLGNWKHPKVSNMSGFLAGDKDQLQKCPVYQDALGFVSPTGANEGSAPMQGMSLQGSTARMGGTQLPPIRSYKPITYTSSNLRRMNETGEAEAKRRRFNDGYIDNNSNNDIPRGISPKPSNGLSSVQPLLSSFSMNQLNGGTIPTVPSLTNITSQMGALPSLDRITTNQINLPDPSRDEAFDNSIKQMTPMTSAFMNANTTIPSSTLNGNMNMNGAGTANTDTSANGSALSTLTSPQGSDLASNSATQYKPDLEDFLMQNSNFNGLMINPSSLVEVVGGYNDPNNLGRNDAVDFLPVDNVEIDGVGIKINYHLLTSIYVTSILSYTVLEDDANDEK
What is the function of this protein?
Regulation of oxygen dependent gene expression.  It modulates the expression of Iso-1 (CYP1) and Iso-2 (CYP3) cytochrome c.  In response to heme, promotes transcription of genes encoding functions required for respiration, controlling oxidative damage and repression of anaerobic genes.  Binds to the sequence 5'-CGGNNNTNNCGG-3' (By similarity).  Is non-functional in terms of iso-1 cytochrome c expression in strain S288c and its derivatives.
What are the official names of this protein?
Heme-responsive zinc finger transcription factor HAP1, CYP1 activatory protein, Heme activator protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMA_SALEP
Sequence: MTPEHLPTEQYEAQLAEKVARLQSMMAPFSGLVPEVFRSPVSHYRMRAEFRLWHDGDDLYHIMFDQQTKSRIRVDTFPAASQLINTLMKAMIAGVRDNHALRHKLFQIDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELYCGNGNFSLALARNFNRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKRYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHTVSRLALFDQFPYTHHMECGVLLTAR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: TRI54_MOUSE
Sequence: MNFTVGFKPLLGDAHNMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHAKAEQHLMCEEHEDEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFETLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEGSSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFSVSVEHVAEMLRTIDFQPGAAGDEEDDDMALDGEEGNAGLEEERLDVPEGSGLH
What is the function of this protein?
May bind and stabilize microtubules during myotubes formation.
What are the official names of this protein?
Tripartite motif-containing protein 54, Muscle-specific RING finger protein, MuRF, Muscle-specific RING finger protein 3, MuRF-3, MuRF3, RING finger protein 30.
Protein: THIK_SHIBS
Sequence: MPFRSNNPITRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPASIAPKPHLYLRDWMVVDYLPGAVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDTALELAAVWVENTEQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: Y1482_ARCFU
Sequence: MDTSELERRAKICLSVVTFSTSYSLDAGVVVLAFLGIQRFRRSSKGAKIPEFLWVTWQSFIKVLSLLNGFVQHQKRYIFIRVCIY
What are the official names of this protein?
Uncharacterized protein AF_1482.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS2_ERYLH
Sequence: MAAPTVTMQQLIEAGSHFGHQTHRWNPRMKPYIFGARNGVHIIDLSQTVPLMARALDFVHATANAGGKVLFVGTKRQAQEPIAEAARSSGQHFVNHRWLGGMLTNWQTISKSIKELKSLEEQLSGETHGLTKKEVLNLTRKRDKLELSLGGIRDMGGVPDVMVVIDANKEDLAIKEANVLGIPVVGILDTNVDPSGIAFPVPGNDDAARAVRLYCDAFAQAASKNGGGANVGEMENPPVEATADA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: GSA_LARHH
Sequence: MDRNQQLFERAKHVIPGGVNSPVRAFGSVGGSPRFIKRAQGAYMWDADDRRLIDYIGSWGPMILGHAHPAVVEAVQQAAVHGLSFGTPTEAEIGIAEEICKLMPSIERVRLVSSGTEATMSAIRLARGFTGRDAIIKFEGCYHGHSDSLLVKAGSGLLTFGNPSSAGVPEDFTRHTLVLEYNNVEQLERTFAEIGERIACVILEPVAGNMNLIRPSAAFVQALRTLTQQHGSVLIYDEVMTGFRVALGGAQSLHGIQPDLTTLGKVVGGGMPIGAFGGRADIMNCIAPLGSVYQAGTLSGNPVAVAAGLATLRLIQQPGFYDALAARTARLVDGMVAAAREAGIPFSGDCVGGMFGLYFAADVPTSYAEVTASDRERFNAFFHAMLEAGVYLAPSAYEAGFVSAAHTDADIDATVDAARQAFARI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1765_SYNY3
Sequence: MTVTPKQIYNYTVLLEKELDGGYHAFCPMLKGCHSQGDTFEEAIQNITEAIELYIESLIAEHQPVPKEDLIVKPLSILV
What are the official names of this protein?
UPF0150 protein ssr1765.
What is the protein family that this protein belongs to?
Belongs to the UPF0150 family.
Protein: DGAT2_YEAST
Sequence: MSGTFNDIRRRKKEEGSPTAGITERHENKSLSSIDKREQTLKPQLESCCPLATPFERRLQTLAVAWHTSSFVLFSIFTLFAISTPALWVLAIPYMIYFFFDRSPATGEVVNRYSLRFRSLPIWKWYCDYFPISLIKTVNLKPTFTLSKNKRVNEKNYKIRLWPTKYSINLKSNSTIDYRNQECTGPTYLFGYHPHGIGALGAFGAFATEGCNYSKIFPGIPISLMTLVTQFHIPLYRDYLLALGISSVSRKNALRTLSKNQSICIVVGGARESLLSSTNGTQLILNKRKGFIKLAIQTGNINLVPVFAFGEVDCYNVLSTKKDSVLGKMQLWFKENFGFTIPIFYARGLFNYDFGLLPFRAPINVVVGRPIYVEKKITNPPDDVVNHFHDLYIAELKRLYYENREKYGVPDAELKIVG
What is the function of this protein?
Catalyzes the terminal and only committed step in triacylglycerol (TAG) synthesis by using diacylglycerol (DAG) and fatty acyl-CoA as substrates.  Required for storage lipid synthesis.  Major DAG esterifying enzyme in stationary phase when TAG production is particularly active.  Involved in lipid particle synthesis from the endoplasmic reticulum, promoting localized TAG production at discrete ER subdomains, and in ergosterol biosynthesis (PubMed:11741946, PubMed:11751830, PubMed:11751875, PubMed:14640980, PubMed:15155725, PubMed:21321129, PubMed:32349126).  Also has monoacylglycerol acyltransferase (MGAT) activity, catalyzing the acyl-CoA-dependent esterification of monoacylglycerol to diacylglycerol (PubMed:20554061).  Can also utilize ceramide instead of DAG, acylating the ceramides by attaching a fatty acid to the hydroxy group on the first carbon atom of the long-chain base to produce 1-O-acylceramides (PubMed:22738231).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 1, DGAT, Acyl-CoA-dependent diacylglycerol O-acyltransferase, Acyl-CoA:monoacylglycerol acyltransferase, MGAT, Triacylglycerol synthase, TAG synthase.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Lipid droplet. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to sites of lipid droplet biogenesis in the endoplasmic reticulum.
Protein: SYH_MESFL
Sequence: MKTNKNKTNIKMIGFYHFFYFVKPYYLLINENVIIFKAKGDFMIQKPRGTQDLFLNNSKEWNAVEEKFRKVLNLFNYGEIITPMFESKELFVRGVGDSSDIVSKEMYEFTDRKGREYVLRPEGTAPTVRALIENKLYIQENLPYKTFYIGPIFRYERPQAGRYRQFNQLGVETFGIDSISHDVELISLGQSFLKELKINKDVIVEMNYLISGNERKEYELELKKYLNLFDDLCSDCEIRINKNVLRVLDCKIDGNKFAEAPKMTLFASQENKERLNKTFDQLKQLGIEAKINFNLVRGLDYYTGLVFEFKNIKTDQAIIAGGSYNNLVEELGGPNLPASGFAIGIERIMMILSDQEIKVADEDELDLFIIPLSDDAQFLTNKLLLEARTANLKVDTNWNIKNLKAGFKSAERLKSKNIVIIGENSINSDIYAIKDQKSGETKELKFKDIVKYLKGEK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAPOA_BOVIN
Sequence: MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCLLTQKLVETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVDMKIAAMHVKRKQLHQLLPSHVLQKKKKHSTEGVKLTPLNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSLPQINSSESSGGTSSESIPQTATQPAISSPPKPTVSRVVSSTRLVNPPPRPSGNAAAKIPNPIVGVKRTSSPHKEESPKKTKTEEDETSEDANCLALSGHDKTETKEQLDTETSTTQSETIQTATSLLASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.  Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites.  May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.
What are the official names of this protein?
Poly(A) polymerase alpha, PAP-alpha, Polynucleotide adenylyltransferase alpha.
What is the protein family that this protein belongs to?
Belongs to the poly(A) polymerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROB_SYNE7
Sequence: MSETLVVKIGTSSLTNPHHPGLALSTIAGLVEVICQLRRQGYNVVLVSSGAVGVGCTRLGLRDRPSRIAQRQAIAAVGQGRLMRTYDDLFTTLGQPIAQVLLTRGDLAQRQRYINAYQTFQELFELGVVPIVNENDTVAVEELKFGDNDTLSALVASLVEAQWLFLLTDVDRLYTADPRQDPNAKPITIVHDLSELESIQAGGQGSRWGTGGMATKLTAAKIATQASVRTVITQGRSPENLLKILAGEAIGTWFEPQPETVNARKRWIAHGLVPTGKLLLDAGAVQAIQAGGKSLLAAGIQAIEGDFEAQDAVQLCDLNGTEIARGLVNYDSHELQQIRGCQSDQIVQILGYEGAETIVHRDNLVLS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_BURO1
Sequence: MVPWLGPDDPFPSIERALGPATGAPGLLAASADLLPSRLIDAYLRGIFPWYSDGQPVLWWSPDPRMILVPAEFKVSPSLRKTLKRVLRAPEWEVRVDHDFAGVMRACAQAPRRGQRGTWITAEIIDAYTSLYRSGNAHSIETWHDGRRVGGLYGVSFGRMFFGESMYADVTDASKIALAALIAHLREQRLEMIDCQQNTSHLASLGGREIARKAFVAHVRSAVAEPPIPWQFDKRVLAALTSPAETAAPTGTER
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
Protein: RPOA_PSAJU
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAVSMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGTSFEENKNRFTPPLFTFQKRLTNLKKNKKGIPLNCIFIDQLELTSRTYNCLKRANIHTLLDLLSKTEEDLMRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: QUEF_ACIB3
Sequence: MSVEQSLLGKETQYPTSYQPDVLFPIARAQSREKYAHIQGITQGKDWWHVFEISWLNAHGIPQVAIGRITLPASSPNLIESKSLKLYFNSLNFTQFDSTQSFIETVEKDLSAAAGAKVELTLFQVDDLEISKPQGICIDDLMPERLEQHPDATLLKLDESGEEIEVELYSHLLRSNCPVTGQPDWGTVFIRFKGKKPCYRSLLAYIISYRQHNGFHEQCVEQIFADIWQNLQPEKLMVYATYTRRGGLDINPCRVSDLTWMPKPIRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXA_NATPD
Sequence: MSEQQTASLGEFTFECGESIPDLELAYETYGEFTGDNAVLVCHALTGSAHVAGGRRRSDTSGQAHAWWDDIVGPGKAVDTTDYYVICANIPGSCYGSSGPPSTNPETGEPWGTTFPAVTVGDWTRAQRRLLDHLGVPHLHAVVGGSVGGMNVLDWAKRHPDHVNRVAVVAAAARLDPQCLALDAIARRAITTDPNWNGGDYYGEDPPVEGLALARQIGHVMYLSKSSMQDKFGRRSSGIDAGRDSFEMDPAAGFFPYREVESYLDYQGEKFARRFDANSYLYLTRAMDNYDLASGYESDRDALAAFDGEALLISFTGDWHFTVEQSEAVADAFRESGTDTAHHVVDSDHGHDAFLVEPDRVGPPLDDFLVDGVAGKAVSDTTPDDDDGDEFAPVHTSLFSD
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABRD_ABRPR
Sequence: QDQVIKFTTEGATSQSYKQFIEALRQRLTGGLIHDIPVLPDPTTVEERNRYITVELSNSERESIEVGIDVTNAYVVAYRAGSQSYFLRDAPASASTYLFPGTQRYSLRFDGSYGDLERWAHQTREEISLGLQALTHAISFLRSGASNDEEKARTLIVIIQMASEAARYRCISNRVGVSIRTGTAFQPDPAMLSLENNWDNLSGGVQQSVQDAFPNNVILSSINRQPVVVDSLSHPTVAVLALMLFVCNPPNANQSPLLIRSIVEESKICSSRYEPTVRIGGRDGMCVDVYDDGYHNGNRIIAWKCKDRLEENQLWTLKSDLTIRSNGKCLTTEGYAPGNYVMIYDCTSAVAEATYWEIWDNGTIINPKSALVLSAESSSMGGTLTVQTNEYLMRQGWRTGNNTSPFVTSISGYSDLCMQAQGSNVWLADCDNNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSPIVLMACSNGWASQRWLFKNDGSIYSLYDDMVMDVKGSDPSLKQIILWPYTGKPNQIWLTLF
What is the function of this protein?
The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.
What are the official names of this protein?
Abrin-d.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: RL31_RICPR
Sequence: MKNGIHPEYKKLLIKVGSNIFETMSTHPIGEILMDVDFRKHPAWNKDSGNVVNQSNKSVSDFNKRFAGLSFDSKKEAS
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: VLIP_GAHVM
Sequence: MPSKSIADHHAGYGVALAIVALLLIHGTALVMIFSDIKVGSQPQDLKDQLSYPSNYDAYTSHISGADHGHSEMWTDINPPSRKPLHGDSLDIKTNEEHITLSSPRTSTKTTNENGHEKDSKDIKFSFSTNRHPISVSPTTDIVSIAVSHNNPMGGDTWQVSRNGPNTVHVPIYGKPILRLNGEELSTQIAHMSMWDELAGSFKTFAATAESFHMITTTHLFNKTLHKDVFFVVHGWHGITNDTHIFLSAVRLLTRMMPTSCIIYLSWESQGAIGTAADAILLARRVNITQFLSAMPSQLRIHCMGHSLGSYVCGSICRQYHSLMSGICKGILGINPYEVLFSAPDLYARMHVDTIRLDAEYVAIFATTSQYLSTSDSDADEYIIVNDAVFMNSVCANPYEWNIHLCTTGYGELKSCERFGAANVTTSPGVVEDGSQICLRMLPIIAVLQSLDLKSSYPLLRIAPPDASNEVTHLPSIWNIYVVGKDYRYSTYAKNDSLWYSSAICAGDTGFSIPSVFTVFAPPSISLRVRAAVQQSSTIYKNITIYSAFLKNTSRYYPTVTLETLGPILSAYAWRGRMHNSSYYPLPLPEQEIMEYKCTHIDRTYTCIPTDLIYATTVWRQIFSMGHIFPVYPSNNCLPYRPTNAIIWRRPVLEIGVWNNITASFQRNKQLMALTFENHNTATNTTLLTFHDVCRESKIRSVVYFEYDWLETSMNITVLIPGLYTLRWFFPFEIIEMPVRVSYNNSFAQALTTSRV
What is the function of this protein?
May play a role in host immune modulation since the protein is secreted and provides an advantage for growth in vivo while it is completely dispensable in cell culture.
What are the official names of this protein?
Virulence factor MDV010, Viral lipase homolog, vLIP.
What are the subcellular locations of this protein?
Secreted.
Protein: HCS1_YEAST
Sequence: MNKELASKFLSSIKHEREQDIQTTSRLLTTLSIQQLVQNGLAINNIHLENIRSGLIGKLYMELGPNLAVNDKIQRGDIKVGDIVLVRPAKTKVNTKTKPKVKKVSEDSNGEQAECSGVVYKMSDTQITIALEESQDVIATTFYSYSKLYILKTTNVVTYNRMESTMRKLSEISSPIQDKIIQYLVNERPFIPNTNSFQNIKSFLNPNLNDSQKTAINFAINNDLTIIHGPPGTGKTFTLIELIQQLLIKNPEERILICGPSNISVDTILERLTPLVPNNLLLRIGHPARLLDSNKRHSLDILSKKNTIVKDISQEIDKLIQENKKLKNYKQRKENWNEIKLLRKDLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCSLYRDDPNFQLFDTLIIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNLETTLFDRIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPTVDATPSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNVPENSIGVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEVGFLKEERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWSEWCEENADVRYPNIDDYL
What is the function of this protein?
DNA polymerase alpha-associated DNA helicase which may be involved in DNA replication.
What are the official names of this protein?
DNA polymerase alpha-associated DNA helicase A.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VATB1_ARATH
Sequence: MGTNDLDIEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGSTRRGQVLEVDGEKAVVQVFEGTSGIDNKFTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTVDLLEDHGEDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPTPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYANYAIGKDVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVMQGAYDTRNIFQSLDLAWTLLRIFPRELLHRIPAKTLDQFYSRDSTS
What is the function of this protein?
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase subunit B1, V-ATPase subunit B1, V-ATPase 57 kDa subunit, Vacuolar H(+)-ATPase subunit B isoform 1, Vacuolar proton pump subunit B1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: IF6_SULIK
Sequence: MNLQRLSIFGTDNIGVYIYTNNKYTVVPRGLDSETKENIVQILGTELIEAEISRSFLLGIFISGNDNGILLPKSTIDDEFRFLKENLRDCRVEVLNSKVTALGNTILTNNKAALIYPEFNDIEEKIIKETLGVEEIRRGKIAQMITVGSVGVVTNKGGLVHVDTSEKELKELEKLFGVKIDIGTVNFGSVFIRSGLVANDKGTLVGASTTGPEILRIQKALGE
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: YCJF_SALPA
Sequence: MSEPLKPRIDFAEPLKEEPTSAFKAQQTFSEAESRTFAPAAIDERPEDEGVAEAAVDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIVGAGVGSVVTEWRRLWRLRQRAHERDEARELLHSHSVGKGRAFCEKLAQQAGIDQSHPVLQRWYAAIHETQNDREIVGLYANLVQPVLDAQARREISRFAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFRLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDNDKPRLGDFRRQLIGQLKETLQKSKSSPEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYL2_SULAC
Sequence: MKISEKWQKEWENKRVFDATPDPNKKKFFTTIAFPYPNSPFHLGHGRTYVTGDIYARYMRMRGYNVLFPMAFHYTGTPIIAMADDVAKGDKELIDIFKSIYEIPDDVISKLVDPLFMANYFKEEIKQAMKEIGLSIDWRREFTTIDPEFSSFIIWQFRKLQEKGFIVRDTHPVGWCPVHHIPVGMHDTKGDMEPEIGEFVLIYFDSDMGILPVATLRPETVFGAIAVWVNPHESYSIVEIDGKKYVMSEKASSKLSFQIDNLKVITVVKGSELVKHSAVNPITGKEVPIIGANFVDPLTGTGVVMSVPAHAPFDYFYLKKTKSELSIISVIRVEGMGETLAKDLVEKSNPQNDNDLKKLTEQVYRIEYNKGVMIDITKLVKPEYVEELKPLVNLPVPAARQKITEFITQKGLGRKIYEIMNRPVYCRCGNEVVVKILKDQWFLDYGNQEWKDLARKSIESIRFIPPEIKKDFEFVVDWLQKRACARTRGLGTPLPWDKKWIIESLSDSTIYMAFYTIAHRLKEHKLKPSQLTYEFWEYIMLGNGNPDEISKISGIPVEVIKAMRDEFLYWYPLDVRHSGKDLVPNHLSFFIFNHAAIFPHQLWPKGIAVNGFVLYDGKKMSKSLRNIVPLRKAIRMYSPDVIRIALTTNADIGSDVNFSDSYAKSIIDTLKNYYDLLEKLKEFKGEDEGFPEKWLKSKFYQMVINVTQYMDSLDLRSSSNEILYNFSSYINEYFELVRSEGREPNGKLLSQILQIWIKLLSPFAPHFAEELWHKIGKNTLVSLESWPIIDQSNVDLFIDLTHTYHRKLLNDIQAILSVYKDTPKSIKIFVANKEFLNVLRDAINIVQKGGQLRQLMEIHKPKGKQDARLYQKIYEEAREIDDDMKKLVTNFDFDEKDLLDKGLKYLSYKLGIKEIRILDASEMDRTKYNKDALPLRPAIIIE
What are the official names of this protein?
Leucine--tRNA ligase 2, Leucyl-tRNA synthetase 2, LeuRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAA3_ARATH
Sequence: MAAFATAEACDSNAELISNGDLRALHPIFKIYGQRRCFSGPIVTLKVFEDNVLVRNQLETKGEGGVLVIDGGGSMRCALVGGNLGQLAQNNGWSGIVVNGCVRDVDEINDCDVGVRALGSNPLKSTKKGHGEKNVPVHIGGTLIRDGEWLYADSDGILISKTELSV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase 3, HMG aldolase 3, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog 3, RraA-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: RS4_MESM1
Sequence: MSRYVGPVFKRSRRFGFSILETGKEFVKGKQRQYAPGQHGQRRGKLSDFGIHQLEKQKVRFMYGINERQFRNTFAIANKAKGVTGTAFLQLLESRLDNIVYRMGFAQTRRQARQLVNHGHFLLNGKKADIPSQRINVGDTIELRAKSQNVPTILASIETRVVAPWIEKDKFKGKLIRVPERKELNQEINEALIVEFYNK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.