PharMolix/UniProtQA huggingface dataset:
Protein: KDM8_BOVIN
Sequence: MAGPSTLWETLQALLPHTKEELKLELGEKVEGSVLMLLQEAAELFLGGQRRECLQTCEVLLDYSWEKLNTGPWQHVDKDWRRVYAFGCLLKAVCLCEPPGDAASVAAALKACDMGLLMGAAILGDILLKVAAVLQKYLLSGKRPAPGPSQEPPGTKKARNDHVPIPDVTTERTVPRLHCPSLQYFKKHFLVPGRPVILEGVANHWPCMKKWSLEYIQEVAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIREEPKDIGYLAQHQLFDQIPELKQDISIPDYCCLGDGEEEEITINAWFGPQGTVSPLHQDPQQNFLAQVMGRKYIRLYSPQESEALYPHDTHLLHNTSQVDVENPDLEKFPRFAEAPFLSCVLSPGEVLFIPVKHWHYVRALDLSFSVSFWWS
What is the function of this protein?
Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase.  Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation.  Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4.  After initial cleavage, continues to digest histones tails via its aminopeptidase activity.  Upon DNA damage, cleaves the N-terminal tail of histone H3 at monomethylated lysine residues, preferably at monomethylated 'Lys-9' (H3K9me1).  The histone variant H3F3A is the major target for cleavage.  Additionnally, acts as Fe(2+) and 2-oxoglutarate-dependent monooxygenase, catalyzing (R)-stereospecific hydroxylation at C-3 of 'Arg-137' of RPS6 and 'Arg-141' of RCCD1, but the biological significance of this activity remains to be established.  Regulates mitosis through different mechanisms: Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with RCCD1.  Possibly together with RCCD1, is involved in proper mitotic spindle organization and chromosome segregation.  Negatively regulates cell cycle repressor CDKN1A/p21, which controls G1/S phase transition.  Required for G2/M phase cell cycle progression.  Regulates expression of CCNA1/cyclin-A1, leading to cancer cell proliferation.  Also, plays a role in regulating alpha-tubulin acetylation and cytoskeletal microtubule stability involved in epithelial to mesenchymal transition (By similarity).  Regulates the circadian gene expression in the liver (By similarity).  Represses the transcriptional activator activity of the CLOCK-BMAL1 heterodimer in a catalytically-independent manner (By similarity).  Negatively regulates the protein stability and function of CRY1; required for AMPK-FBXL3-induced CRY1 degradation (By similarity).
What are the official names of this protein?
Bifunctional peptidase and arginyl-hydroxylase JMJD5, JmjC domain-containing protein 5, Jumonji C domain-containing protein 5, L-arginine (3R)-hydroxylase KDM8.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with trimethylated 'Lys-9' of histone H3 (H3K9me3).
Protein: HBA_CAIMO
Sequence: MVLSAADKTNVKGVFSKIGGHAEEYGAETLERMFIAYPQTKTYFPHFDLQHGSAQIKAHGKKVAAALVEAVNHIDDIAGALSKLSDLHAQKLRVDPVNFKFLGHCFLVVVAIHHPAALTPEVHASLDKFMCAVGAVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ILVH_GALSU
Sequence: MKHTLSVLVEDESGVLTRISGLFARRGFNIDSLAVGPAEKAGISRITMVIRGDNRIIEQITKHLYKLVNVLKIQDITNIPCVERELMLIKVKTGENKRNEILEIANIFRARVVDLSESFIILEITGDPGKIAAIEKLLEKYGICEIARTGKIALTRESKINTEILRLNTMINNDKIRGGGT
What are the official names of this protein?
Acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FOLD_MYCBP
Sequence: MGAIMLDGKATRDEIFGDLKPRVAALDAAGRTPGLGTILVGDDPGSQAYVRGKHADCAKVGITSIRRDLPADISTATLNETIDELNANPDCTGYIVQLPLPKHLDENAALERVDPAKDADGLHPTNLGRLVLGTPAPLPCTPRGIVHLLRRYDISIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLPALTRQADIVVAAVGVAHLLTADMVRPGAAVIDVGVSRTDDGLVGDVHPDVWELAGHVSPNPGGVGPLTRAFLLTNVVELAERR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RSMC_PSEU2
Sequence: MDPRSEVLLRQAELFQGSLLLVGLPADDLLGKLPDARGWCWHAGDQAALDARFEGRVDFGVEAPQTGFEAAVLFLPKARDLTDYLLNALASRLAGRELFLVGEKRGGIEAAAKQLSPFGRARKLDSARHCQLWQVTVEHAPQAVSLDSLARPYQIELQDGPLTVVSLPGVFSHGRLDRGSALLLENIDKLPSGNLLDFGCGAGVLGAAIKRRYPHNEVIMLDVDAFATASSRLTLAANGLQAQVLTGDGIDAAPMGLNTILSNPPFHVGVHTDYMATENLLRKARQHLKSGGELRLVANNFLRYQPLIEEHVGQCEVRAQGNGFKIYSAKRP
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_MYCLE
Sequence: MFLGTHTPKLDDKGRLTLPAKFRDALVGGLMVTKSQDHSLAVYPRAEFEQLARRASKMSRSNPEARAFLRNLAAGTDEQHPDMQGRITLSADHRRYANLSKDCVVIGAVDYLEIWDAQAWHDYQQTHEENFSAASDEALGDII
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: IXTPA_METMA
Sequence: MHKIVFVTGNKGKFAEVRDILKNFGIEAIQNKDGYPELQEDELEPIAANGAQYVANKLNMPVMVDDSGIFINALNGFPGPYSRFVEDKLGNPKVLKLMEGEKDRSAYFKTVIGYCEPGQEPLVFPGVVEGKIAYEERGTGGFGYDPIFEYNGMTFGELGDEEKNKVSHRRRAVDNFLEWFIGGA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: Y819_METVS
Sequence: MGNYHVTLQASYIAKNVEDVEDAIGVAISQIGKLLNKGSLDYVDIDVGLTICPKCGEPIDCVLVVAKTAIVGILLSMKVFNAESPEHAVRIAKSSIGRALKDIPLEDVDVVEI
What are the official names of this protein?
UPF0212 protein Mevan_0819.
What is the protein family that this protein belongs to?
Belongs to the UPF0212 family.
Protein: RSMG_BACFR
Sequence: MNTTEQTSSLPSAGGENGVKLLLKYFPDLTEEQRKQFAALYELYIDWNSKINVISRKDIENLYEHHVLHSLGIARIIRFRAGSSVMDLGTGGGFPGIPLAILFPDTKFHLVDSIGKKVRVATEVANAIGLKNVTFRHARAEEEKQTFDFVVSRAVMPLADLIKIIRKNISPKQQNALPNGLICLKGGELEHEAMPFKHKTSMHNLNEDFDEEFFQTKKVVYVTI
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_GLUOX
Sequence: MKLVAIGRLKAGPERELFERYAGRIRPALTVTELAPSKGSVQEQKRQDAAALLGACPDNALIVALDEGGKTPDSLRLAEMLSRWQESGRPIHFLIGGAEGLDSSVIQRADSVISLGKLTWPHMLVRVLIAEQVFRAQAINTGHPYHRESRPD
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_BACC4
Sequence: MTKITVVGAGSWGTALAMVLADNGHDVRIWGNRPELMDEINTKHENSRYLPGITLPSTIVAYSSLEEALVDVNTVLLVVPTKAYRDVLQEMKEIVTEPITWIHASKGIEPGTSKRISEVIEEEIPEHLIKDVVVLSGPSHAEEVGLRQATTVTSAAKRMEAAEEVQDLFMNSYFRVYTNPDIVGVELGGALKNIIALAAGITDGLGLGDNAKAALMTRGLTEIARLGRKMGGNPLTFAGLTGMGDLIVTCTSVHSRNWRAGNMLGKGHSLEEVLESMGMVVEGVRTTKAAHELAEKMEVEMPITAALYDVLFNGNNVKDAVGSLMGRVRKHEVEAIPDLL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_CHLCV
Sequence: MSLDKGTKEEITKKFQLHEKDTGSADVQIAILTEHITELKEHLKRSPKDQNSRLALLKLVGQRRKLLEYLNSTDTERYKNLITRLNLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PPE20_MYCTO
Sequence: MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQGQAAEAFVAAYMPFLAWLIQASADCVEMAAQQHVVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSRSALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYDDYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAITGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYLVGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGARASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
What are the official names of this protein?
Uncharacterized PPE family protein PPE20.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-3 / type VII secretion system (T7SS).
Protein: GYRB_STRP6
Sequence: MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEGLHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVETVFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVVADLEIIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKRSGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQETVMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVISVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKARIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNREFQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTDADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQLKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVFDMLMGDRVEPRRDFIEENAVYSTLDI
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YC0C_SCHPO
Sequence: MGQTNSRHSLIETDEPTTSSRVSMLVDRVKLLWKRYTTPLSTEDGSREAHFAVPSENYADTPSRNTPNSSNGFPSETLVTSSAHCSTQPHKDEAYSHHGYSSTMALDDSSLAQTYHEYEEGTSGNSPLRRAIGSYDFLHPRPSGNSSRLDRNSSRPFTSSFHSAPFLSSYGSSNDPSQERVNEYSLPSNSNSTYTTPLQSINNEHPLPTVLENNALLNNSGNSPSLINHLRQYLNQDFSRLHQSPSPIPNSNDNDSQTRRSSWSSIASAFNDFPEEFPNASNPEAHSNFTPLNGNDESTVNMLSRLLSAAAIETVASIMNSEARNMDSQNMANGEPSRFRSVDGSFEQFLTDLRSGNLTNVLQNSSQNGNDQISSDPESNSSDLQYLRMFRFPSFHQSHNQPASNNEASDTNGPALVPVLIVCMRSISETSEDHAPTMTQENQSLHNESRENISINDITERMAQSTEFSTDLPPTFERSNSTFSHPEPTRSDFSQAFTPVSDFPANLFPGSRNLFPTSNSGNQSTSSFSRYNQPTVSVDLRNSSILRRAQEPVNGSTGENHIGDDYISSLLDSSNSNSQRPFSTVPSESNVFSRNASGNFSMSQTHQPTTDNTSSFSTQPGRLSTGLHHFPSDRDLLSNQTRRSSLARSYRFEEQLSVDDNTSDFSTLASNGAADMVTQTHSEGTFSNSTHGDWLIYVFGGLFPEHHPVLSTVSLFSDNPMYEDLLALTTYLGPAKKPVASHEDVKRSGGLFAYFDDASLSSADSCLICLETYTNGDICRKLQACKHFFHQACIDQWLTTGNNSCPLCRAHGVTTQAEEEN
What are the official names of this protein?
Uncharacterized RING finger protein C4G3.12c.
Protein: JAGN_CAEBR
Sequence: MSSRGVRAAGTDGNDFQNRQRIAQHYQESAQYKSVLKWFFVPHFLILVFMWLKVGSEFLRYNFGWKNAFFERLDMPAAYPWEYVWCLSFIPIVLALSSFQRNKLKVLHYAYYAEFICGIFPCMIGLGGQLPELLEYANDMEGSNTPTFKGIFPMVIIWYIFFAVALQIHGFSMYFMHHLAAAWAPVKRD
What are the official names of this protein?
Protein jagunal homolog.
What is the protein family that this protein belongs to?
Belongs to the jagunal family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MSHR_HAPGR
Sequence: MPVQGSPRSLLGAVNSTPTATPHLRPAANQTGPQCLEVSIPDGLFLCLGLVSLVENTLVVAAIAKNRNLHSPMYCFVCCLALSDLLVSVSSVLETAVLLLLGAGALAAQATVVQLLGNVIDVLLCSSMVSSLFFLGAIAMDRYISIFYALRYHSIVTLARARRAIAAIWAASMLSSTLFIAYCDHTAALLCLVVFFLAMLVLMAVLYVHMLTQACQHAQGIARLHKRQRPVQQGWGLKGAATLAILLGVFFLCWGPFFLHLTLIAVCPQHPTCSCIFKNFRLFLALIVCNAIVDPLIYAFRSQELCKTLKELLLFSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYNT_HALAU
Sequence: ILQKAVLDCLKAAGSSLSKAAITAIYNKIT
What is the function of this protein?
Shows antibacterial activity against both Gram-positive and Gram-negative bacteria.  Its antimicrobial activity is optimal at NaCl concentrations below 100 mM, suggesting that the antimicrobial actions of this peptide may take place intracellularly rather than extracellularly.  Has no activity against the fungus C. albicans.  Has modest hemolytic activity.
What are the official names of this protein?
Dicynthaurin.
What are the subcellular locations of this protein?
Secreted.
Protein: U79B3_ARATH
Sequence: MGGLKFHVLMYPWFATGHMTPFLFLANKLAEKGHTVTFLLPKKSLKQLEHFNLFPHNIVFRSVTVPHVDGLPVGTETASEIPVTSTDLLMSAMDLTRDQVEAVVRAVEPDLIFFDFAHWIPEVARDFGLKTVKYVVVSASTIASMLVPGGELGVPPPGYPSSKVLLRKQDAYTMKKLEPTNTIDVGPNLLERVTTSLMNSDVIAIRTAREIEGNFCDYIEKHCRKKVLLTGPVFPEPDKTRELEERWVKWLSGYEPDSVVFCALGSQVILEKDQFQELCLGMELTGSPFLVAVKPPRGSSTIQEALPEGFEERVKGRGLVWGGWVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIVLVPQLGDQVLNTRLLSDELKVSVEVAREETGWFSKESLCDAVNSVMKRDSELGNLVRKNHTKWRETVASPGLMTGYVDAFVESLQDLVSGTTHD
What are the official names of this protein?
UDP-glycosyltransferase 79B3.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: MURC_SYNE7
Sequence: MTIAVDLQGRPFHFIGIGGIGMSALAQVVTERQLPVSGSDIRRSHITDRLAQLGAQIFDRQAATNLEFFQEAVSAGQSPQVICSTAIHAHNEEYQAAIDLGCPVFHRSDLLAALLRVYESIAVAGTHGKTTTSGLIAYLLYQAGLDPTVVIGGEVNALGGNARLGQGRHLVAEADESDGSLVKLQAAIGIITNIELDHPDHYCDLEAVISTFKTFSDNCSQLIANWDCPTVRDRLPGTISYSLDPARGADYTVDQVSFRGSGTQARIWERGELLGRIHLPLLEAHNLSNALAAIAACRHLGMDFASIREGLAGFEGARRRFEFRGSAQGIQFVDDYAHHPSELAATLAAARLQIDSGCSRLPEVPKRLVAIFQPHRYSRTQAFLAEFAQSFGPADLVLISDIYAAGERNPGQLSGQTLADAIAQYQANVHYAPDLEAVEQRLHQLLQPGDLALFLGAGNLNQVIPRLLDHYACDRSAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCNA_SHISS
Sequence: MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIAIKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIIGTAFWMFWRTWRGERNWLENMHEYDYEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHANDIKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLALTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR
What is the function of this protein?
Efflux system for nickel and cobalt.
What are the official names of this protein?
Nickel/cobalt efflux system RcnA.
What is the protein family that this protein belongs to?
Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FTSW_NITSI
Sequence: MIYQANNQKQRVLADFDQALVWSVVLLLSIGLIMIYSASIAIAEAQFGADRASYYLLRHSAYLAVGLLLGLVTFQVPMRIWQKYVTYLFMISVLLLALVLVPGIGHEVNGSQRWISLYVVNIQPSEFVKLFMVMYAADYVSRKAADLNSFLKGFLPITVVLSIVGFLLLLEPDFGAFFVVTALVMSILFMGGVSLKIFIALIGILAIGLYELILSSEYRMARVVAFMDPWADPYGKGYQLSHALIAFGRGEWFGVGLGGSVEKLFYLPEAHTDFLLSVLAEELGFVGVAAVILLFIWLIMRTFVIGRLAAKLGNTFSALVAQGIGIWIGVQALINMGVNMGVLPTKGLTLPLLSFGGSSITANCIALAVILRIDWENRQRLRGLNV
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: NUOA_ANADE
Sequence: MLTPLQIYFPIGVVLLVAVVLAFTMLGLANVLGPRRPSLVKQTPFECGSEPIGSARERFGVKFYVVALLFIVFDIEAIFLYPWAVLLLPDGQGYPGLGWPGFISMGIFVFTLVAGLVYVWKKGVLDWAD
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_SULAC
Sequence: MKHIISAYNFSRDELEDIFALTDKYSKNLNDTRKILSGKTISIAFFEPSTRTYLSFQKAIINLGGDVIGFSGEESTSVAKGENLADTIRMLNNYSDGIVMRHKYDGASRFASEISDIPVINAGDGKHEHPTQAVIDIYTINKHFNTIDGLVFALLGDLKYARTVNSLLRILTRFRPKLVYLISPQLLRARKEILDELNYPVKEVENPFEVINEVDVLYVTRIQKERFVDEMEYEKIKGSYIVSLDLANKMKKDSIILHPLPRVNEIDRKVDKTTKAKYFEQASYGVPVRMSILTKIYGE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CREA_ASPOR
Sequence: MPPPASSVDFTNLLNPQNNETGSAPSTPVDSSKAPSTPSSTQSNSTMASSVSLLPPLMKGARPATEEARQDLPRPYKCPLCDRAFHRLEHQTRHIRTHTGEKPHACQFPGCTKRFSRSDELTRHSRIHNNPNSRRSNKAHLAAAAAAAAAGQENAMVNVTNAGSLMPPPTKPMTRSAPVSQVGSPDVSPPHSFSNYAGHMRSNLGPYARNTERASSGMDINLLATAASQVERDEQHFGFHAGPRNHHLFASRHHTGRGLPSLSAYAISHSMSRSHSHEDEDGYTHRVKRSRPNSPNSTAPSSPTFSHDSLSPTPDHTPLATPAHSPRLRPLGSSELHLPSIRHLSLHHTPALAPMEPQPEGPNYYSPSQSHGPTISDIMSRPDGTQRKLPVPQVPKVAVQDMLNPSAGFSSVSSSTNNSVAGNDLAERF
What is the function of this protein?
Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter.  Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
What are the official names of this protein?
DNA-binding protein creA, Carbon catabolite repressor A.
What is the protein family that this protein belongs to?
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPS38_YEAST
Sequence: MKRFLLSRRQRHLRMICFHNISLFRANGDSKLIKEYGDGFIPCFFILESIRGELLYVSEVQSGSLRKLSFQELPKLTGASTMIVLKLVGLVPSDILCTISSDKNGIIDDKWCVLCTYTIDLNKLQPINEDTVLITGTNAPVLDLIDGSYTLAAEKIKPLKGLVSSHKRNISQVKIKFSLAYSSLLKLNKLLEYSSQVHEEINEISSKIEDDFLSLKNQNHWYMRTVQKSIETLEKEVLQRKKSKKNIEMAQLESNDTINHSKTELSLMSQDESINDDYGSIYSRFVQIKDRLDQLRFKKLYQLIGIFHSTDLFNSDRGYIYFEKPSSVNDVINRLKLKPLNIEILLRQAGESTKHREYVNSQLGYYLLFLHLTAIQIFKAPLPYRLMYYGSTSVIDSQYPLYFTDQMISKHQAKLIKAIHYFNADILQFKQILENYRPT
What is the function of this protein?
Involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II.  This complex is required for the endosome-to-Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes (probably through generating a specific pool of phosphatidylinositol 3-phosphate allowing the recruitment of the retromer complex proteins to the endosome).  Mediates the interaction between VPS30 and the VPS34-VPS15 core complex, leading to the recruitment of VPS30 to the membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 38.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: PRP1_BOMMO
Sequence: MSDAKNNLLLFFDRPSEPCFMQKGEENAVFEIPDNYYPEKYQRVSNAIGNRFGSDAGRMIPIRNIALPNLDLPMELPYNEQFSLFVPKHRKLAGRLIDIFMGMRDVEDLQSVCSYCQLRINPYMFNYCLSVAILHRPDTKGLSIPTFAESFPDKFMDPKVFRQAREVSSVVPSGARMPIVIPSNYTASDTEPEQRVAYFREDIGINLHHWHWHLVYPFDAADRAIVNKDRRGELFYYMHQQIIARYNVERMCNNLSRVRRYNNFRAAIEEGYFPKLDSTVASRAWPPRFAGTTIRDLDRPVDQIRSDVSELETWRDRFLQAIENMSVMLPNGRQLPLDEETGIDVLGNLMESSIISRNRPYYGDLHNMGHVFISYSHDPDHRHLEQFGVMGDSATAMRDPVFYRWHAYIDDIFHLYKYKLTPYGNDRLDFPNIRVSSVSIEGGGTPNTLNTLWEQSTVDLGRGMDFTPRGSVLARFTHLQHDEYNYVIEVNNTGGSSVMGMFRIFIAPTVDESGKPFSFDEQRKLMIELDKFSQGVKPGNNTIRRKSIDSSVTIPYERTFRNQADRPADPGTAGAAEFDFCGCGWPHHMLVPKGTTQGYPMVLFVMVSNWNDDRVEQDLVGSCNDAASYCGIRDRKYPDRRAMGFPFDRPAPAATTLSDFLRPNMAVRDCIVRFTDRTRQRGQQG
What is the function of this protein?
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.  Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone.
What are the official names of this protein?
Phenoloxidase subunit 1, PO 1, Tyrosinase 1.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Secreted.