PharMolix/UniProtQA huggingface dataset:
Protein: FXYD3_MOUSE
Sequence: MQEVVLSLLVLLAGLPTLDANDPENKNDPFYYDWYSLRVGGLICAGILCALGIIVLMSGKCKCKFRQKPSHRPGEGPPLITPGSAHNC
What is the function of this protein?
Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell (PubMed:15743908).  Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity).  Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity).
What are the official names of this protein?
FXYD domain-containing ion transport regulator 3, Chloride conductance inducer protein Mat-8, Mammary tumor 8 kDa protein, Phospholemman-like, Sodium/potassium-transporting ATPase subunit FXYD3.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LIPA_KLEP7
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSSRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPQKLAQTIADMGLRYVVVTSVDRDDLRDGGAQHFADCISAIREKNPSIKIETLVPDFRGRMDRALDILTVTPPDVFNHNLENVPRLYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNDEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPEEFEEMKAEAMAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_STRS2
Sequence: MSRIGNKVITLPAGVELAQNNGVVTVKGPKGELTREFPTAIEIRVEGAEVTLHRPNDSKEMKTIHGTSRANLNNMVVGVSEGFKKELEMRGVGYRAQLAGNKLTLAVGKSHPDEVVAPEGITFEVPTPTQIVVSGINKEVVGQTAAYIRSLRAPEPYKGKGIRYVGEFVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TUBE_BPT4
Sequence: MFVDDVTRAFESGDFARPNLFQVEISYLGQNFTFQCKATALPAGIVEKIPVGFMNRKINVAGDRTFDDWTVTVMNDEAHDARQKFVDWQSIAAGQGNEITGGKPAEYKKSAIVRQYARDAKTVTKEIEIKGLWPTNVGELQLDWDSNNEIQTFEVTLALDYWE
What is the function of this protein?
Forms the central cylindrical rigid tube, which is surrounded by the outer contractile sheath assembled from gp18 subunits.  The tail tube first 2 annuli are formed by gp48 and gp54, which are in continuation of the spike complex.  During infection, contraction of the sheath drives the central tube through the host outer membrane, creating a channel for DNA ejection from the capsid into the host cell.
What are the official names of this protein?
Tail tube protein gp19, Gene product 19, gp19.
What is the protein family that this protein belongs to?
Belongs to the T4-like viruses Gp19 protein family.
What are the subcellular locations of this protein?
Virion.
Protein: SPEE_KLEP7
Sequence: MADNPLWHETLHDHFGQYFSVDNVLYHEKTDHQDLIIFDNRAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGNAKHVLIIGGGDGAMLREVSRHRSIETITMVEIDAGVVSFCRQYLPNHNAGAYDDPRFTLVIDDGVNFVNQTTQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQDEAVGSHRKLSHYFRDVSFYQAAIPTYYGGIMTFAWASDNEALRHLSSEIIQARFHKANLTCRYYNPAIHTAAFALPQYLHDALSAP
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_BUTUM
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: H2BS2_ECHES
Sequence: MPKSPSKSSPRKGSPRKASPKRGGKGAKRA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.2, sperm.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: EST1_THEFU
Sequence: MEIVIRTGSGDVRGSKENGIAVFRGIPYAEPPVGAHRFTAPRPPRPWDGVRDATEFSATAPRPPYPEAIGALLIERFIPGDDYLTLNVWTPDPNAVGLPVMVWIHGGAFTNGSGSEPVYDGAAFARDGVVFVSFNYRLGIIGFADLPDAPSNRGLLDQIAALEWVRDNIARFGGDPGNVTVFGESAGAMSVCTLMATPRARGLFRRAILQSGAGNMAVAAEDATTIAAVIAHRLGVEPTAAALAHVPVAQLLDVQQQVAQEIQGAPDPAVWGERIAGGSVLLPFAPVIDGELLSQRPAEAIAGGAGHDVDLLFGTTTDEYRLFLAPTGLLPFITSDYVTAHLAKSGLDADAAKAYTAEGRGEEPGDILASIITDQVFRIPALRIAESRVDAPARTFGYEFAWRTPQLDGILGACHAVELPFVFRTLDRAASLVGTNPPEELAETVHNAWVRFATSGDPGWPAWNPETRSVMRFDHPVSEMVTDPYPATRALWDGVPL
What are the official names of this protein?
Carboxylesterase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: E2AA_ECOLX
Sequence: MIKHVLLFFVFISFSVSANDFFRADSRTPDEIRRAGGLLPRGQQEAYERGTPININLYEHARGTVTGNTRYNDGYVSTTVTLRQAHLIGQNILGSYNEYYIYVVAPAPNLFDVNGVLGRYSPYPSENEFAALGGIPLSQIIGWYRVSFGAIEGGMQRNRDYRGDLFRGLTVAPNEDGYQLAGFPSNFPAWREMPWSTFAPEQCVPNNKEFKGGVCISATNVLSKYDLMNFKKLLKRRLALTFFMSEDDFIGVHGERDEL
What is the function of this protein?
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
What are the official names of this protein?
Heat-labile enterotoxin IIA, A chain, LT-IIA.
What is the protein family that this protein belongs to?
Belongs to the enterotoxin A family.
Protein: ORFC_ELHVK
Sequence: MRYLSAEHDDFEKSRIFKSVLTVGAGVAPNTNSCATFKAKSVKNSVERMHTMQRDEIRDEAARHAACPRYTDMNVLNIVRDFDQGAFGGPVDDNLDIFEAEVPEAGRRAAGTAAPRDNTAVPELELMRAMHRASLNDRPPAAGSAQRGSAGSRQPRDNLTPTAADTTGAQASVDLISRPIYQTEQPRPPASNVQQQAAAAALRRQQQPPPGVRRPRSRQARQQQPQQPARPPQTTETQTSNNSNTNNTTATRQVFEQQGPSTIQGRPPTETEILNELFNCHAEIPPLEHVTGHDGYTITTPLFTSVPYQNQTRRSRPQGDNEVPPPTEGDLRPVIPRIPYESETGTETQDDTATGGEITTLVAPSQSDRIQLQIPRSIRNLTRRRAAAAAASQTGSADTPIVTPQPEQTAVPPVLRPPVFRAPSGQSSVSQQQPIQTSNVITTDTTTGTSAPSGDNDSRRAWSPPPWVRRESSSNEPSRQSQSVIEPDEQRYANLPPPPDWLFKRHGVPPRPLRVLTSIDDMSSGCDDTMTQSGTTSSTTRQPPPPNPFAPSRRPQSSGGRCRPPQNGSQGPQHSDDDDSPYPLGSRRQPVPYGTGSVTTTQPSGQLPSDDRGRPAPERRQQPTSRQTVAQTNIIPNTSGGADDDNTPPDRNRLTTFLDEMKRTNWETVEEYLNAIEEDRQRRETEAEHTNLLLPESHTGVTPQRSNNPFMPQVDLDTIPTQDRQETQRQRPSPKPKPKSLREYRRRDPLTGMGRSYTDGSTTSDGDSSDNSWSDESRRPRRRVGSTLVRPPRSHSAEDASGAGGKIKGTARKSPHSSRAPAQQGAGTADLTELAGMASLNLKSPSPRTKLTRSSSLKSPGTTTRDTQQTSHPLTRSASLSSKSSNPFMPRPPDSGGSSDGNTGSSQTSVSTLGINAQQCKFRVPNAHKMFTMVNGKPRLPRMRSAWYSSDDGGESGLECLRTPAPTRKTGGRGGSKITVDVKKIMATAKGSQQAKKCLDKIIKHAGEAERYALQQPSPEPPAGSISARAAPPPKPRTGTRSASQDRSNTRETVPVATDLIDISSAPSSLTQQVSTSASQTTCDGIQLFSVAPPGGSTSQSVQKPSSIPLQPIVTGPSTMTSQSVTDHDGSSVTKKPVISQGTFKHTSQSQPSSEQPAPGEPQPDDQLRDFIAELEGTDVPAPPVPEQPQSTVTNTQTQDVLPSQGSSKTTQQTTSSTQKSSKTGSAPTSGPKSALSKTKSSTSDTASGKSVTRKGSAASSTDPTTKPTRKVSINATEPKKGSKSSTKQSTKTSTQPSDKNNILLNAKVVTIDGDRINIADSNISVFAPTQPTATATQPVTSESTPALPPQLSIPQGQQSVTNIFAPIVPPTNTLSAQATSCTQPLEQRVSLNQPDNPPRRRVVSSFAEQIRNLEVDELKILRQQVRERIANERQQQDSPMDVDRRLALDTLEDMLVSEESAAPTPLPMDTGRFTPKSDVDMS
What are the official names of this protein?
Protein ORF C.
Protein: ACP_AGRVS
Sequence: MSDIAERVKKIVIDHLGVEADKVVEGASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAADSILTVGDAVKFIEKAQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB8A_YEAST
Sequence: MTIFSRFSYFDSLFSFKKQEPSPIEIIYCNENNGFINIKSLESPTDDSMEADISDREMATILTRNRNNLGKVAIDKKGVNNHCIDLNELKKGLVANEHKLDNDNSTRHQNTYSPEDSVEFDRFDDKQSRILKCSTRRSYLRYKK
What are the official names of this protein?
Putative uncharacterized protein YBR285W.
Protein: GREA_ALIB4
Sequence: MEKEPMTLAGYNKVTAELDFLKKTERPETVIALDEARQLGDLKENAEYHSAKEKLKLIDIQIAELNAVISKAVIIDPTTLPHDRVSFGSTIDLVDVDTDEEFTYTIVGGVESSAEKGMISFNSPLAKQLMGKEAGDELNATLPGGAKTFEILKVYYKEISL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: IF3_METC4
Sequence: MPAPQKDGPRANRDIRGVRDVQLIDQDGQNRGVVPFFDALAMAEEVGLDLVEIAPNSVPPVCKFLDYGRFRFNEQKKQNEARKRQKTVEVKEIKLRPGIDKHDYEVKMKAVQRFFEEGDKVKVTLRFRGREIAHQDIGLRLLERVKQETQEIAKVESEPMLEGRQMIMILAPR
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBT44_XENTR
Sequence: MGVKTFTHNSPGHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSEFFRTKLVGQAEDSSQCVLDLHHVTVTGFTPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNTQQEKILDTGQENPVNCNNFRDGSLSPVSSECSVVERTIPICRESRRKRKSYIVMSPESPLKCNTQTSSPQVLNPTPSYAEARNQSVDSSHAFPWTFPFGIDRRIQSEKVKQIESRTLELPGPSEVARRVTDYVACESTKVSSPLVMEDDVRVKVERLSDEEVHEEVSQPVSASQSSMSDQQTVPGSEQVQEDLLISPQSSSIGSIDEGVSEGLPTLQSTASTSVHADDDDRLENVQYPYQLYLAPTTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEAIS
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 44.
What are the subcellular locations of this protein?
Nucleus.
Protein: KLK10_RAT
Sequence: MWFLILFLALSLGGIDAAPPGQSRIVGGYKCEKNSQPWQVAIINEYLCGGVLIDPSWVITAAHCYSNYYHVLLGRNNLFEDEPFAQYRFVNQSFPHPDYKPFLMRNHTRQRGDDYSNDLMLLHLSEPADITDGVKVIDLPTEEPKVGSTCLASGWGSTKPLNWELPDDLQCVNIHLLSNEKCIEAYEQKVTDLMLCAGEMDGRKDTCKGDSGGPLICDGVLQGITSWGNVPCAEPYNPGVYTKLIKFTSWIKEVMKENP
What is the function of this protein?
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.  This protein may be involved in the regulation of renal function.
What are the official names of this protein?
Glandular kallikrein-10, K10, rGK-10, Endopeptidase K, Proteinase B, T-kininogenase, Tissue kallikrein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein: VMA21_YEAS7
Sequence: MAVDVPRAVINKLMLFTAAMVVLPVLTFFIIQQFTPNTLISGGLAAAMANVVLIVYIVVAFREDTEDHKVDGNKKED
What is the function of this protein?
Functions with VOA1 in assembly of the integral membrane sector (also called V0 sector) of the V-ATPase in the endoplasmic reticulum.  Escorts the assembled V0 sector in COPII vesicles.  Also required for normal packaging of the SNARE BOS1 and possibly the ER to Golgi transport receptor ERV29.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VMA21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: PPK5_PERAM
Sequence: GGGGSGETSGMWFGPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Pyrokinin-5, Pea-PK-5, FXPRL-amide, PerAm-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DGTL1_CERS5
Sequence: MLAPYACQPGESRGRQQPESMSTFRSPFQRDRDRIIHSSAFRRLKHKTQVFVEHEGDYYRTRLTHSIEVAQVARTISGVLGLNTDLAECIALAHDLGHTPFGHTGEDALAKLMEPYGGFDHNAQAMRIVTRLERHYAEFDGLNLTWESLEGIAKHNGPVEGPLPYALAEANAQWDLELHTYASAEAQVAAIADDVAYSHHDLHDGLRSGLFTEDDLMELPVTAPAFAEVDALYPGLEPMRRRHEALRRVFGRMVEDVIAVAQGRLEAAQPKSVEEIRQMGATVIRFSKPLYQELKVIRSFLFHRMYRAPSVMKERAKVTAVVNDLFPLFMRQPELLPQEWRRDVEAAEDETTLARIVADYVAGMTDRFALQEHARLCG
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: CALR_MACFU
Sequence: MLLSVPLLLGLLGLAAAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
What is the function of this protein?
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle.  This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER.  Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity).  Involved in maternal gene expression regulation.  May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).  Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).
What are the official names of this protein?
Calreticulin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen. Cytoplasmic vesicle, secretory vesicle, Cortical granule. Cytolytic granule. Note=Also found in cell surface (T cells), cytosol and extracellular matrix. During oocyte maturation and after parthenogenetic activation accumulates in cortical granules. In pronuclear and early cleaved embryos localizes weakly to cytoplasm around nucleus and more strongly in the region near the cortex (By similarity). In cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation (By similarity).
Protein: DXR_MALP2
Sequence: MLEGEKMENKKKKVLVFGATGNIGFSSLEIIEKENYELVGFSFNNNYEKALEIINRFPNALVFSPSVKTKNTVNSFEELLEKTNPDIILNALVGFSGLHITLLALKNNVDLALANKESLVVAGWLIEDLKRSSSSRIYPVDSEHSSLYDSLKNNNKEIKELIITCSGGPFYKKEFNELLNINFADAVKHPNWNMGKKISIDSATMMNKCFEIIEAYYLFNTKKIKVYQHGQSIIHSMIKFTDNSYIANMSVPDMKLSIQQGLSGYESKTNLINDLSFNNLNLTFSEIDLDKWKPIHWAYDFLENQNRAIPIIMNAANEEAIVLFEENKIKFLDIFEIIEKAIIALENTEVNDLKDILNLNKNTRKYVYDFSKNKFRY
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RNJ_HELPJ
Sequence: MTDNNQNNENHENSSENSKDHHEARAGAFERFTNRKKRFRENAQKNAESSNHETLSHHKKEHRPNKKPNNHHKPKHASQKTRNYAKEELDNNKVEGVTEILHVNERGTLGFHKELKKGVEANNKIQVEHLNPHYKMNLNSKASVKITPLGGLGEIGGNMMVIETPKSAIVIDAGMSFPKEGLFGVDILIPDFSYLHQIKDKIAGIIITHAHEDHIGATPYLFKELQFPLYGTPLSLGLIGSKFDEHGLKKYRSYFKIVEKRCPISVGEFIIEWIHITHSIIDSSALAIQTKAGTIIHTGDFKIDHTPVDNLPTDLYRLAHYGEKGVMLLLSDSTNSHKSGTTPSESTIAPAFDTLFKEAQGRVIMSTFSSNIHRVHQAIQYGIKYNRKIAVIGRSMEKNLDIARELGYIHLPYQSFIEANEVAKYPDNEVLIVTTGSQGETMSALYRMATDEHRHISIKPNDLVIISAKAIPGNEASVSAVLNFLIKKEAKVAYQEFDNIHVSGHAAQEEQKLMLRLIKPKFFLPVHGEYNHVARHKQTAIACGVPEKNIYLMEDGDQVEVGPAFIKKVGTIKSGKSYVDNQSNLSIDTSIVQQREEVASAGVFAATIFVNKNKQALLESSQFSSLGLVGFKDEKHLIKEIQGGLEVLLKSSNAEILNNPKKLEDHTRNFIRKALFKKFRKYPAIICHAHSF
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J, RNase J.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_ICTPU
Sequence: MAPSRNGMILNPHFHKDWQKRVRTWFNQPARKLRRRKARQAKARRIAPRPVAGPLRPIVRCPTVRYNTKVRAGRGFTLEELKAAGINKRVARTIGIAVDPRRRNRSTESLHVNVQRLKVYRSKLILFPRKVSAPKKGDSTEEEVKMATQLTGPVMPIKIVHKKEKARMITEEEKKFNAFANLRMARANARLFGIRAKRAKEAAEQDVEKKK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  As part of the LSU, it is probably required for its formation and the maturation of rRNAs.
What are the official names of this protein?
60S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TO1C_HADVE
Sequence: SSTCIPSGQPCPYNENCCSQSCTFKENENGNTVKRCD
What is the function of this protein?
Inhibits insect, but not mammalian, voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-hexatoxin-Hv1c, Omega-HXTX-Hv1c, Omega-atracotoxin-Hv1c, Omega-AcTx-Hv1c.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 08 (Shiva) family. 01 (omega toxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MCP2_SALTY
Sequence: MFNRIRVVTMLMMVLGVFALLQLVSGGLLFSSLQHNQQGFVISNELRQQQSELTSTWDLMLQTRINLSRSAARMMMDASNQQSSAKTDLLQNAKTTLAQAAAHYANFKNMTPLPAMAEASANVDEKYQRYQAALAELIQFLDNGNMDAYFAQPTQGMQNALGEALGNYARVSENLYRQTFDQSAHDYRFAQWQLGVLAVVLVLILMVVWFGIRHALLNPLARVITHIREIASGDLTKTLTVSGRNEIGELAGTVEHMQRSLIDTVTQVREGSDAIYSGTSEIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASETARHGGKVVDGVVNTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMTDIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLASRPLAVNKPEMRLSVNAQSGNTPQSLAARDDANWETF
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.  Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
What are the official names of this protein?
Methyl-accepting chemotaxis protein II, MCP-II, Aspartate chemoreceptor protein.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CAPSD_CARMS
Sequence: MENKGEKIAMNPTVQTLAQKGDKLAVKLVTRGWASLSTNQKRRAEMLAGYTPAILAFTPRRPRMTNSPPRTSRNSPGQAGKSMTMSKTELLCTVKGTTGVIPSFEDWVVSPRNVAVFPQLSLLATNFNKYRITALTVKYSPACSFETNGRVALGFNDDASDTPPTTKVGFYDLGKHVETAAQTAKDLVIPVDGKTRFIRDSASDDAKLVDFGRLVLSTYGFDKADTVVGELFIQYTIVLSDPTKTAKISQASNDKVSDGPTYVVPSVNGNELQLRVVAAGKWCIIVRGTVEGGFTKPTLIGPGISGDVDYESARPIAICELVTQMEGQMLKITKTSAEQPLKVVVYRM
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.  Also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, p38.
What is the protein family that this protein belongs to?
Belongs to the icosahedral plant coat protein family.
What are the subcellular locations of this protein?
Virion.
Protein: Y3057_KINRD
Sequence: MSGHSKWATTKHKKAVVDAKRAKSFARLIKNIEVAARTGGGDVSGNPTLFDAIQKAKKTSVPADNIDRAVKRGSGAEAGGADWQTIMYEGYGPNGVALLVECLTDNKNRAAMEVRTAMTRNGGSLADPGSVAYMFSRKGVVVIGKEGTDLTEDDVLGAVLDAGAEEVSDQGDTFEVISEATDLAAVRDALKAAGIEYDSAEASFVPSVEVPLDAEGATKVFRLIDALDDCDDVQNVFANYDVSDDVMAALEDA
What are the official names of this protein?
Probable transcriptional regulatory protein Krad_3057.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH3_STAAM
Sequence: MANIVFKLSDKDITTLMSRITFDTENLPQGMKARAKYQNTTVNIYQSGKVMFQGNHAEAVSKELLPQHSQLNTNKTKKKNMANSSLEQTLMYDQFNCIGSDEAGSGDYFGPLTVCAAFVTKEHVPILKTLGVDDSKKLTDTKIVELAEQLVAFIPHSLLTLHNDKYNIQQAKGWTQVKMKAVLHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYALSDIPLPKKTKFETKGESKSLAIAVASIISRYAFITYMDQISKYINMTIPKGAGAKVDVIAAKIIKKYGLSRLDTISKKHFKNREKAQKILKPL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.