PharMolix/UniProtQA huggingface dataset:
Protein: MTSI_SPISQ
Sequence: MSKVENKTKKLRVFEAFAGIGAQRKALEKVRKDEYEIVGLAEWYVPAIVMYQAIHNNFHTKLEYKSVSREEMIDYLENKTLSWNSKNPVSNGYWKRKKDDELKIIYNAIKLSEKEGNIFDIRDLYKRTLKNIDLLTYSFPCQDLSQQGIQKGMKRGSGTRSGLLWEIERALDSTEKNDLPKYLLMENVGALLHKKNEEELNQWKQKLESLGYQNSIEVLNAADFGSSQARRRVFMISTLNEFVELPKGDKKPKSIKKVLNKIVSEKDILNNLLKYNLTEFKKTKSNINKASLIGYSKFNSEGYVYDPEFTGPTLTASGANSRIKIKDGSNIRKMNSDETFLYIGFDSQDGKRVNEIEFLTENQKIFVCGNSISVEVLEAIIDKIGG
What is the function of this protein?
This de novo methylase acts completely and exclusively on CG residues in DNA; methylates unmethylated and hemi-methylated DNA.
What are the official names of this protein?
Orphan methyltransferase M.SssI, M.SssI, CpG DNA methylase, Cytosine-specific methyltransferase SssI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: PDP2_ARATH
Sequence: MSTESERIESVSEANASSLEVGNDQMSEALAGQAQELKTIGDDKEGCGNFASAGDNGMEKVNGFTNLVKETESVNGELDLGTRTENVGGESNQSDKKVLVDSEEVMMVEKRGLLVEKEVEPDMVCSHGADLSDVKVSDGRLDSEDLVQDRKPDGLEKQGTKVEDLDVVCFMGLEPHESKDESILDDEIAHVAAKVKISDSDLVWAKVRSHPWWPGQVFDASAATDKAKKHFKKGSFLVTYFGDCTFAWNEASRIKPFRQHFSQMAKQSSLPDFIDAIDFALEEVSRRIEFGLACSCISEEVYQKIKTQNVINPGIREDSSSIHGGDKVSSAVFFEPANLVGYVKRLACSPSYDATDALQLVSQRAQLLAFNRWKGYTDLPEFMTLQGSVESAPKISPAEEQSSLVEVSDPEPTKSKQVYTKRRKTNLQTEQSSLVEVSDPDKGDCKHDGVFEYEETIVPKKKEKTLAEFIAEKRVSRHNGNTSHEKSGNVPHCEKKRKVVQSKVPKSTKKIKANLQTEDPGSPVSPKNDRKNNLSAGDKITPQKARKSFGIGASILKVANQMHCSTPTRLLPCSDSTSKKAAKSNGSGKSLQEKPKAEALSAREISPSTTLSSPHAASVTKTTSGKSNSVSLDHNLSGELDQVRKEAPSTNLVEDPMLESRDLKDSSKEQVVHEDKKEAANVADEKSIMDSNLTGEKISGLDLREQPSNKNCSGGSDSCKEDVSAE
What is the function of this protein?
Together with PDP1, PDP3 and PDP6, interacts with MSI4/FVE and MSI5 to suppress FLC, MAF4 and MAF5 expression by regulating the function of the PRC2 complex and modulating H3K27me3 level, thereby promoting flowering.
What are the official names of this protein?
PWWP domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the PDP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: END4_ECO57
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: KGUA_PSESM
Sequence: MTHITGTLYIISAPSGAGKTSLVKALMDAQQEPQHGAQAKIRVSVSHTTRAMRPGEVDGVNYNFVDRAEFVRMIEHGDFLEQAEVFGNLYGTSQSHLQQTLDEGHDLILEIDWQGARQVRTQMPQARSIFILPPSQQALRQRLTNRGQDSDEIIEARMREAVSEMSHYNEYEYVVVNDDFAGALEDLKSIFRANRLTQQHQQEQYSELFQELLA
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_SHISS
Sequence: MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: PLED_CAUVN
Sequence: MSARILVVDDIEANVRLLEAKLTAEYYEVSTAMDGPTALAMAARDLPDIILLDVMMPGMDGFTVCRKLKDDPTTRHIPVVLITALDGRGDRIQGLESGASDFLTKPIDDVMLFARVRSLTRFKLVIDELRQREASGRRMGVIAGAAARLDGLGGRVLIVDDNERQAQRVAAELGVEHRPVIESDPEKAKISAGGPVDLVIVNAAAKNFDGLRFTAALRSEERTRQLPVLAMVDPDDRGRMVKALEIGVNDILSRPIDPQELSARVKTQIQRKRYTDYLRNNLDHSLELAVTDQLTGLHNRRYMTGQLDSLVKRATLGGDPVSALLIDIDFFKKINDTFGHDIGDEVLREFALRLASNVRAIDLPCRYGGEEFVVIMPDTALADALRIAERIRMHVSGSPFTVAHGREMLNVTISIGVSATAGEGDTPEALLKRADEGVYQAKASGRNAVVGKAA
What is the function of this protein?
Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger.
What are the official names of this protein?
Response regulator PleD, Stalked cell differentiation-controlling protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Phosphorylated PleD localizes to the differentiating pole.
Protein: RL7_CAMHC
Sequence: MAITKEDVLEYISNLSVLELSELVKEFEEKFGVSAAPVMVAGGAGAGAAAAAEEKTEFDLVLTDTGAEKIKVIKAVRAITGLGLKEAKDAVEKTPSVLKEGMNKEDAEKAKADLEAAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: YCF27_GUITH
Sequence: MIKNRCLDIDLETKEKVLIVDDEASIRKILETRLSMIGYFVVTASDGEEALNLFHQEMPDVVILDIMMPKLDGYGVCQEIRKDSDVPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRAVLRRTNKAAFSSHLTTSGIINFNFLTIDLNKRQIYKDNERIRLTGMEFSLLELLISRSGQPFSRADILQEVWGYTPERHVDTRVVDVHISRLRAKLETDPSNPDLILTARGTGYLFQRITDQHVLKT
What is the function of this protein?
Probable promoter-specific protein mediating the interaction between DNA and RNA polymerase.
What are the official names of this protein?
Probable transcriptional regulator ycf27, OmpR-like protein.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPIA_PARXL
Sequence: MTQDELKQLVGQAAADYVNANVPEGSVIGVGTGSTANCFIDALAAGKTRYRGAVSSSLATTARLQSHGFKVLDLNEIDSLPVYVDGADEIDHSGAMIKGGGGALTREKIVASVSDVFVCIADASKLVETLGSFPLPIEVVPMARTSIGRRVTALGGVPVVRVTKEGVPFITDNGNEIIDVKGLRISDPRTLETHVNAWPGVVTVGLFASRGADLCLLGTDTGVDTIRFSKG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: KICS2_XENLA
Sequence: MIPPTSAQVTAEQNVLQTFFSHLGNFSYDKAKDHVEKEKEGNKSAGASWSLMLAALAHLAAAQKAYHSMSFLGQKQGGQLFFSRKDSIRTNYTSLYNELKKVVTTGRNAVGGTAPHLEELLSHLSEQLCYFVQAHMEIADFYEKMYTLSSQKFINAEELVKILEAILKKYSSRFHHPTLSPLESGFQLEVDVLAHLLKAQFLIYEWKFLPALVNLHNAHTKLQTWGQIFEKQKETKKHLFGGQSQKVAQPPHLFLWLMKFKNLLLAKFSFYFHEALSRQTSEMKTLTAKTNPDYFGKISSFIRKYDAVNVSLIYDTRGSENFQGHGYHHPDSYREAPKGMDQYPAVVSLPNDRPIMHWPNVIMIMTDKSADLNTLEKVVHFYDDKVQSTYFLTRPEPNFTIVVIFESKKSERDSHFTSFLNELSQSLKGSRAFASLKPGSKV
What is the function of this protein?
As part of the KICSTOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway.
What are the official names of this protein?
KICSTOR subunit 2.
What is the protein family that this protein belongs to?
Belongs to the KICS2 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: RNC_SHEB9
Sequence: MEPIKNLPRLCRTLSYEFKNIELLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGDTLTIIAQEFKLGDYLYLGPGELKSGGFRRESILADAVEAIIGAVYLDSDLEVCRALLLKWYAERLAEIQPGISQKDAKTLLQEHLQGFKKPLPDYQVINIEGDAHDQTFTVECRIEDLSQSVIGVASSRRKAEQIAAAQVLELLKK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLZ4_COCLU
Sequence: MAHTKIPTALHEQENFLPKKKLIIVILTLGVVLFVINIDHNGLSTLLPTIAEDLGAQKSITWAGSSQLIATTVFSVLYGRLSDIFGRKALFVSALWVFSIAELGCGFATSPKMLYAMRALTGASGGGIGNLSIIIATDVVSLRHRGQYMAVVAPFMVLGNICGPLVAAGVAKSPLTWRGLFWLISPLGVLSAVLAGYILPSTTPTDTFKQNLVKVDWLGSFTSTIAIVGFMVAVSGPGAYHAGYSLLVISLLSVSGVAFLAFLFIEWKLATLPVIPLTIFAIPDVSALLMQTFTLGWVNQANVYFVPIYAQNLRQWSPVISGVLLFPIIAVQVVVSMIAGRWMSKSGQYGLTIRLGVALLLIGSLLETKFGRETHPAYVIIVLLVIGIGVGAANQPMVIAMQAHTKKSERAVVTSSRNFFRFLGSACGVVMSAAILQSTLRTSLPAAYKHLADSPYALAGLNPRERDAIAPAYERAIRHVYIASAAASVLCSLGLFVWKDDGYESRPTENNDDIEHAPARGIEREDEQSSLIYDREPSAVSYGTVEAGEPNRLRRGG
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS).
What are the official names of this protein?
MFS-type transporter clz4, Squalestatin S1 biosynthesis cluster protein clz4, Zaragozic acid A biosynthesis cluster protein 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOC_CHLTE
Sequence: MIFSQGSSPLKGDFSKIKFSIASPESILAHSRGEVLKPETINYRTFKPERDGLMCEKIFGPTKDWECYCGKYKRVRYKGIICDRCGVEVTTKSVRRERMGHISLAVPVVHTWFFRSVPSKIGALLDLSTKELERIIYYEVYVVINPGEPGEKQGIKKFDRLTEEQYFQIITEYEDNQDLEDNDPAKFVAKMGGEAIHMLLKGLNLDEIALNLRKVLKESGSEQKRADALKRLKVVEAFRKSYEPQKRTRKKSTGLFPEEDSPELYIYEGNKPEYMVMEVVPVIPPELRPLVPLEGGRFATSDLNDLYRRVIIRNNRLKKLIDIRAPEVILRNEKRMLQEAVDALFDNSRKANAVKTGESNRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKSMAIELFQPFVIRRLVERGIAKSVKSAKKLIDKKDPVVWDVLEKVIDGHPVLLNRAPTLHRLGIQAFQPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSPEAQLEASLLMLSSHNLILPQSGKPVTVPSQDMVLGMYYLTKARFGDVGQGQLFYSMEEVIIAYNEERVGLHAQIFVKYDGKVDQVSDPVRLVDTLVPEEQAERRAWLKSQIEQKKLLVTTVGRVIFNQHMPEEIGFINKLINKKVAKELIAQLSSEVGNVETARFLDNIKEVGFDYAMRGGLSIGLSDAIVPETKVKHIKNAQRDSAKIIKEYNRGTLTDNERYNQIVDVWQKTSNLVADESYEKLKKDRDGFNPLYMMLDSGARGSREQVRQLTGMRGLIARPQKSMSGQPGEIIENPIISNLKEGLTVLEYFISTHGARKGLSDTSLKTADAGYLTRRLHDVAQDVIVTIDDCGTTRGLHVERNIEEETSGQIKFREKIKGRVAARDIVDVINDKVVVKAGEIITDELAAAIQDNIGVEEAEIRSVLTCESKVGICAKCYGTNLSVHKLVEIGEAVGVIAAQSIGEPGTQLTLRTFHQGGAAQGGIAETETKAFYEGQVELEDVKSVEHSIITEDGIEETRQIVIQKNGKLNIIDPDSGKVLKRYVVPHGAHLNVEHGQMVRKEQVLFSSEPNSTQIIAEMPGFAKFIDIEKGVTYKEEVDPQTGFAQHTIINWRSKLRASETREPRVAIVSESGEIRKTYPVPIKSNLYVEDGQKIVPGDIIAKVPRNLDRVGGDITAGLPKVTELFEARIPTDPAIVSEIDGYVSFGSQRRSSKEIRVKNDFGEEKVYYVQVGKHVLATEGDEVKAGDPLTDGAVSPQDILRIQGPNAVQQYLVNEIQKVYQINAGVEINDKHLEVIVRQMLQKVRVEEPGDTDLLPGDLIDRSTFIEANEAVAEKVRVIDRGDAPARIIEGQLYKQRDITKLNRELRRNGKSLITIEPALQATSHPVLLGITSAALQTESVISAASFQETTKVLTDAAVAGKVDHLVGLKENVIVGKLIPAGTGLRKYRSIRLRDNEAEEAEAVEAASDEEI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RS7_BACAH
Sequence: MPRKGPVAKRDVLPDPMYNSKLVTRLINKMMVDGKKGKSQTILYNAFDIVSERTGKEPMEVFEQALKNIMPVLEVRARRVGGANYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNAGASVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: DEF_MYCGE
Sequence: MTFQPTKTWLVFDDNALINKPTEAVNFPIDEQIETCIKKMIAYVDASYDGKAQEYDIIPGIGIAANQIGYWKQLFYIHLNDLNKEKKCLLINPKIIDQSENKAFLESGEGCLSVKKQHKGYVIRSEWITIKGYDWFEKKEITIKATGLFGMCLQHEFDHLQGRFFYQRINPLNPWFKKPEWKVINPTLKTSNG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: DET2_ARATH
Sequence: MEEIADKTFFRYCLLTLIFAGPPTAVLLKFLQAPYGKHNRTGWGPTVSPPIAWFVMESPTLWLTLLLFPFGRHALNPKSLLLFSPYLIHYFHRTIIYPLRLFRSSFPAGKNGFPITIAALAFTFNLLNGYIQARWVSHYKDDYEDGNWFWWRFVIGMVVFITGMYINITSDRTLVRLKKENRGGYVIPRGGWFELVSCPNYFGEAIEWLGWAVMTWSWAGIGFFLYTCSNLFPRARASHKWYIAKFKEEYPKTRKAVIPFVY
What is the function of this protein?
Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide (BL); acts at the second step in brassinolide biosynthesis in the 5alpha-reduction of (24R)- 24-methylcholest-4-en-3-one, which is further modified to form campestanol.  Can use progesterone, testosterone, androstenedione and campestenone as substrate.  Catalyzes also the conversion of campest-4-en-3-one (campesta-4-en-3-one, 4-en-3-one) to campest-3-one (campesta-3-one, 3-one), of (22S,24R)-22-hydroxyergost-4-en-3-one (22-hydroxy-campesta-4-en-3-one, 22-OH-4-en-3-one) to (22S,24R)-22-hydroxy-5alpha-ergostan-3-one (22-hydroxy-campesta-3-one, 22-OH-3-one), and of (22R,23R)-22,23-dihydroxy-5alpha-campestan-3-one (22,23,diOH-4-en-3-one) to (22R,23R)-22,23-dihydroxycampest-4-en-3-one (6-deoxo3DT) (PubMed:22822057).  Required for the brassinosteroid- (BR) dependent regulation of seed size and shape as well as embryo development (PubMed:23771896).
What are the official names of this protein?
Steroid 5-alpha-reductase DET2, (22R,23R)-22,23-dihydroxycampest-4-en-3-one synthase, (22S,24R)-22-hydroxy-5alpha-ergostan-3-one synthase, Campest-3-one synthase, Protein COMPACT ROSETTE 1, Protein DEETIOLATED 2, AtDET2.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CCT12_ARATH
Sequence: MDEALNENASGSESDASSVASNLHDDEIIPWFFSREEIERNSPSRRDGIDLKTETRLRDSYCTFLEILGERLKVPQVTIATAIFFCHRFFLRQSHAKNDRQTIATVCMLLAGKVEETPVTLEDVIIASYERIHKKDLAGAQRKEVYDQQKELVLIGEELVLSTLNFDLCISHPYKPLVEAIKKYMVEDAKTQLAQFAWNFVNDCLRTTLCLQYQPHHIAAGAILLAAELPTVDLQSYREVLCQEFDITPCQLEDIRGQILELYERIPTSQESKVESSGGVAVVHQPISRDMASTEKCPSSDIEGGSSQVNLSQSDDHSVHDGSRSEGIGEVNSESEAQKNLQDHSVGNIMVEKSDDVGVVQLKKDLQLHQEEVESKQEKDKKSFEKDITKIDLMDEKDLTESEVEDEINKTMQTGRQIFMKVEDPDDNMTVEHSEIRNANNSGVDDELVADTCLINDSDL
What are the official names of this protein?
Cyclin-T1-2, CycT1;2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin T subfamily.
Protein: COAD_GEOMG
Sequence: MPRKVAVYPGSFDPITYGHLDIIDRGLRIFDEIIVAVARNSAKNSLFSIDERVDMIQRVLADNVRARVDTFDGLLVDYVLSQNATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMMTSVPFGYLSSSIVKEVSSLNGPIDGLVPPLVREALKDKFSKPR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_PETMO
Sequence: MKSPKVPKPTIKRLAMYNRFLRELREEGIPKTSSHEIAEALNIKASQVRKDLSYFGEFGKRGVGYDVENLCLKIHKILGTERVWNVAIIGVGNLGRAISHYPELEKYKFKIVAAYDVDKRKINSILLPGIPIKHIKELKNKNDELDFEIAILTVPSNVAQEVANILIEAGVKGILNFAPVTLNSDDRVVIENVDFVISLKTLTYEIVSKYD
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUS_NDVU
Sequence: MGSRSSTRIPVPLMLTVRVALALSCVCPTSSLDGRPLAAAGIVVTGDKAVNIYTSSQTGSIIVKLLPNMPKDKEACAKAPLEAYNRTLTTLLTPLGDSIRRIQESVTTSGGGKQGRLIGAIIGGAALGVATAAQITAASALILANQNAANILRLKESIAATNEAVHEVTDGLSQLAVAVGKMQQFVNDQFNKTAQELDCIKITQQVGVELNLYLTELTTVFGPQITSPALTQLTIQALYNLAGGNMDYLLTKLGVGNNQLSSLIGSGLITGNPILYDSQTQLLGIQVTLPSVGNLNNMRATYLETLSVSTTKGFASALVPKVVTQVGSVIEELDTSYCIETDLDLYCTRIVTFPMSPGIYSCLSGNTSACMYSKTEGALTTPYMTLKGSVIANCKMTTCRSADPPGIISQNYGEAVSLIDRQSCNVLSLDGITLRLSGEFDATYQKNISIQDSQVIVTGNLDISTELGNVNNSISNALDKLEESNSKLDKVNVKLTSTSALITYIVLTVISLVCGILSLVLACYLMYKQKAQQKTLLWLGNNTLDQMRATTKM
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with HN at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: Y2448_EDWI9
Sequence: MDHRLLEIIACPVCNGKLSFNQEHQELVCKIDRLAFPLRDGIPVMLESEARPLPQEEN
What are the official names of this protein?
UPF0434 protein NT01EI_2448.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: CNG_ICTPU
Sequence: MTGQAALERSVSSHRLSVRSRLEGEAERAESAISRTDGDDDTCSELQRVTALELPSAEMLEAFTQRRPLARLVNLVLSLREWAHKSLVETEQRPDSFLERFRGPQAANDQSAAPADAPKKTFKERWEGFVVSQSDDIYYYWLFFIALASLYNWIMLVARACFDQLQDENFFLWVGLDYLCDVIYILDTCIRLRTGYLEQGLLVKDLAKLRDNYIRTLQFKLDFLSILPTELLFFVTGYVPQLRFNRLLRFSRMFEFFDRTETRTNYPNAFRICNLILYILVIIHWNACIYYAISKALGLSSDTWVYSGQNKTLSFCYVYCFYWSTLTLTTIGEMPPPVKDEEYVFVVFDFLVGVLIFATIVGNVGSMIANMNATRAEFQTRIDAIKHYMHFRKVNRTLETRVIKWFDYLWTNKKTVDEQEVLKNLPDKLRAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPQVYSPGDYICRKGDIGKEMYIIKEGQLAVVADDGVTQFALLTAGGCFGEISILNIQGSKMGNRRTANIRSIGYSDLFCLSKDDLMEAVAEYPDAQKVLEERGREILRKQGLLDESVAAGGLGVIDTEEKVERLDASLDILQTRFARLLGEFTSTQRRLKQRITALERQLCHTGLGLLSDNEAEGEHAGVPTHTHADIHAQPETHTRTSAETNSEEET
What is the function of this protein?
This cyclic nucleotide-gated channel is activated equally well by both cAMP and cGMP.
What are the official names of this protein?
Cyclic nucleotide-gated cation channel.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PEPE_ECO57
Sequence: MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQTWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGLLAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGEEAVPLEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAD_GUITH
Sequence: MSETLNLQIPSPTFEGSTGGWLRAAETEEKYAITWTSPKEQVFEMPTGGAAIMRKGENLLYLARKEQCLALGTQVKTSFKITDYKIYRIFPSGEVQYLHPKDGVFPEKVNPGRIGVGNVSHSIGKNLNPAQIKFTNKSFCD
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.
What are the official names of this protein?
Photosystem I reaction center subunit II, Photosystem I 16 kDa polypeptide, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RS13_ANAD2
Sequence: MARIAGVDLPREKRIEVSLQYIYGIGKTSAKLILERANVSPVTRTKDLTDDEVRRIRETIEQNVKVEGDLRREISLNVKRLMDLGCYRGLRHRKGLPVRGQRTHTNARTRKGPKKGLVRKAAAPAPMA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NIKR_HELAH
Sequence: MDTNNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDLIREKLVEDNWIEDSPDDKSKVAVLVVIYDHHQRELNQRMIDIQHASETHVLCTTHIHMDSHNCLETIILKGSSAEVQRLQLEIGGLRGVKFAKLTKASSFESNE
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: ALLC_PSEPF
Sequence: MKAYAVPFEKFVNLADARLGTKIISVTDDWFADANRLFQPTPAVWKEGVFDDNGKWMDGWESRRKRFEGYDSAVIRLGVPGSIKGVDIDTSFFTGNFPPSASLEACFLASGEPDENTQWTEVLSAVELQGNSHHYHEISNDKAFSHLRFNIYPDGGVARLRVYGIPFRDWSAVGDNEQVDLAAALNGGRALACSDEHFGRMSNILNPGRGINMGDGWETARRRTPGNDWVIVALGHPGEIEKIIVDTLHFKGNYPDTCSIQGAFVKGGTDSQIETQSLFWRELLPSQKLEMHAEHTFVEQINALGPITHIRLNVFPDGGVSRLRVLGKVAK
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: PTH_VIBC1
Sequence: MTQPIKLLVGLANPGPEYAKTRHNAGAWVVEELARVHNVTLKNEPKFFGLTGRIMVNGQDLRLLIPTTFMNLSGKAIAALAKFYQIKPEEIMVAHDELDLLPGVAKFKKGGGHGGHNGLRDTISKLGNNKDFYRLRIGIGHPGHKDKVAGFVLGKAPAKEQELLDAAADESVRCLDILIKDGLSKAQNRLHTFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.