PharMolix/UniProtQA huggingface dataset:
Protein: NPY_RAT
Sequence: MMLGNKRMGLCGLTLALSLLVCLGILAEGYPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRYGKRSSPETLISDLLMRESTENAPRTRLEDPSMW
What is the function of this protein?
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
What are the official names of this protein?
Pro-neuropeptide Y.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.
Protein: ITB2_MOUSE
Sequence: MLGLRPSLLLALAGLFFLGSAVSQECTKYKVSSCRDCIQSGPGCSWCQKLNFTGPGEPDSLRCDTRAQLLLKGCPADDIMDPRSIANPEFDQRGQRKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFVNTHPEKLRNPCPNKEKACQPPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAIMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNMYKRSNEFDYPSVGQLAHKLSESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSDDSSNVVQLIKNAYYKLSSRVFLDHSTLPDTLKVTYDSFCSNGASSIGKSRGDCDGVQINNPVTFQVKVMASECIQEQSFVIRALGFTDTVTVQVRPQCECQCRDQSREQSLCGGKGVMECGICRCESGYIGKNCECQTQGRSSQELERNCRKDNSSIVCSGLGDCICGQCVCHTSDVPNKEIFGQYCECDNVNCERYNSQVCGGSDRGSCNCGKCSCKPGYEGSACQCQRSTTGCLNARLVECSGRGHCQCNRCICDEGYQPPMCEDCPSCGSHCRDNHTSCAECLKFDKGPFEKNCSVQCAGMTLQTIPLKKKPCKERDSEGCWITYTLQQKDGRNIYNIHVEDSLECVKGPNVAAIVGGTVVGVVLIGVLLLVIWKALTHLTDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
What is the function of this protein?
Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4.  Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL (By similarity).  Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen.  Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain.  Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain.  Integrin ITGAM/ITGB2 is also a receptor for factor X.  Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1.  Contributes to natural killer cell cytotoxicity (By similarity).  Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (By similarity).  Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation (PubMed:18587400).  Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (By similarity).  In association with alpha subunit ITGAM/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (By similarity).  Integrin ITGAM/ITGB2 plays a critical role in mast cell development and in immune complex-mediated glomerulonephritis.  Mice expressing a null mutation of the ITGAM subunit gene demonstrate increase in neutrophil accumulation, in response to a impaired degranulation and phagocytosis, events that apparently accelerate apoptosis in neutrophils.  These mice develop obesity.
What are the official names of this protein?
Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein.
Protein: NSP5_ROTS1
Sequence: MSLSIDVTSLPSIPSTIYKNESSSTTSTLSGKSIGRSEQYISPDAEAFNKYMLSKSPEDIGPSDSASNDPLTSFSIRSNAVKTNADAGVSMDSSAQSRPSSNVGCDQVDFSLNKGLKVKANLDSSISISTDTKKEKSKQNHKSRKHYPRIEAESDSDDYVLDDSDSDDGKCKNCKYKKKYFALRMRMKQVAMQLIEDL
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RSMG_DEHMC
Sequence: MNELVYGLSALGISLNSVQLGQFETYYQELVDYNSRINLTAITEYKDVQIKHFLDSVSLVLAGIKGDEKLLDVGSGAGFPGLPLKILFPAIQLGLLEATQKKARFLSEITVKLGLSGVEIISQRAEDTAQNPLYRQKYSLVTSRAVADMATLAELTLPFCAVGGRVIAPKKGDIEEEMDRAATAVKKMGGRVFKVIKVELPGLEDGRKLVLLEKISNTPALYPRRAGIPAKTPLI
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZPR1_MOUSE
Sequence: MSASGAVQPGHPGAAVGPSPAAAASPATGPLFRPLSAEDEEQQPTEIESLCMNCYRNGTTRLLLTKIPFFREIIVSSFSCEHCGWNNTEIQSAGRIQDQGVRYTLTVRSQEDMNREVVKTDSATTRIPELDFEIPAFSQKGALTTVEGLISRAISGLEQDQPTRRAVEGAIAERIDEFIGKLKDLKQMASPFTLVIDDPSGNSFVENPHAPQKDNALVITYYDRTPQQAEMLGLQAEAPEEKAEEEDLRNEVLQFNTNCPECNAPAQTNMKLVQIPHFKEVIIMATNCENCGHRTNEVKSGGAVEPLGTRITLHITDPSDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLGDSSNPDQSEKLQEFSQKLGQIIEGKMKAHFIMNDPAGNSYLQNVYAPEDDPEMKVERYKRTFDQNEELGLNDMKTEGYEAGLAPQR
What is the function of this protein?
Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus.  It is involved in the positive regulation of cell cycle progression (By similarity).  Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies.  Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons.  Plays a role in the splicing of cellular pre-mRNAs.  May be involved in H(2)O(2)-induced neuronal cell death.
What are the official names of this protein?
Zinc finger protein ZPR1, Zinc finger protein 259.
What is the protein family that this protein belongs to?
Belongs to the ZPR1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleolus. Cytoplasm, perinuclear region. Nucleus, gem. Nucleus, Cajal body. Cell projection, axon. Cell projection, growth cone. Note=Localized predominantly in the cytoplasm in serum-starved cells growth arrested in G0 of the mitotic cell cycle. Localized both in the nucleus and cytoplasm at the G1 phase of the mitotic cell cycle. Accumulates in the subnuclear bodies during progression into the S phase of the mitotic cell cycle. Diffusely localized throughout the cell during mitosis. Colocalized with NPAT and SMN1 in nuclear bodies including gems (Gemini of coiled bodies) and Cajal bodies in a cell cycle-dependent manner. Colocalized with EGFR in the cytoplasm of quiescent cells. Translocates from the cytoplasm to the nucleus in a epidermal growth factor (EGF)-dependent manner (By similarity). Translocates together with EEF1A1 from the cytoplasm to the nucleolus after treatment with mitogens. Colocalized with SMN1 in Gemini of coiled bodies (gems), Cajal bodies, axon and growth cones of neurons.
Protein: SGPL_DROME
Sequence: MRPFSGSDCLKPVTEGINRAFGAKEPWQVATITATTVLGGVWLWTVICQDENLYIRGKRQFFKFAKKIPAVRRQVETELAKAKNDFETEIKKSNAHLTYSETLPEKGLSKEEILRLVDEHLKTGHYNWRDGRVSGAVYGYKPDLVELVTEVYGKASYTNPLHADLFPGVCKMEAEVVRMACNLFHGNSASCGTMTTGGTESIVMAMKAYRDFAREYKGITRPNIVVPKTVHAAFDKGGQYFNIHVRSVDVDPETYEVDIKKFKRAINRNTILLVGSAPNFPYGTIDDIEAIAALGVKYDIPVHVDACLGSFVVALVRNAGYKLRPFDFEVKGVTSISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAGGIIAACWATMMSFGYDGYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMALYGMAQSIPDRSVIGEVTRLFLHSMYYTPSQK
What is the function of this protein?
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine.  Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development.
What are the official names of this protein?
Sphingosine-1-phosphate lyase, S1PL, SP-lyase, SPL, Sphingosine-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: KR15_ICHVA
Sequence: MAAVNWLKDEPYPEKPTRRNHLSFGPARLPTGDWDWIMTYYKPEAREWLRTMNNPLWSGPEDVLGLLPAGVPVTEKIFVKEVYPGLKGFLQMFIPVKVAGCLLFGFSPLSRTGMATLKTAPVFRGGYAPAAPGIPMQVYAWEMACKIDAAPRLFKWELIVGEYFVRLATLSECSAGGDVGAYIRGGRPISIEAAAVKTRELASTLYLLAQNNVYHGDVKIANTVITEPHGRLGLIDFEMAHPLDMTMSGLREGLEVPIKWDMVCTDEYRAPEGHGPFPDILSAEAQLVWQVGLFMLDVIGIEIIENRNQGLWEQPDFPGLAAREVGIGRSLLACEHRAFLDYLTIARGCLRTNPRERPRLTLLIAQLTKFIREVATQPEH
What are the official names of this protein?
Protein kinase ORF15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RL34_BURMA
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTAGGRKVINARRAKGRKRLAI
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: YJCO_ECO57
Sequence: MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADSWFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSKEGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKADDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDTGCEEFEKLTNG
What are the official names of this protein?
Uncharacterized protein YjcO.
Protein: YHG6_SCHPO
Sequence: MNIYSVGLFYFFLVFIGAQAMDLDITDYQSIDNTVNIMMKDLMNYWNASSQAFVASYWWVTGATMGALLYNYELFNNDTYVDLISSSLLYNAGSGFDYQPSFEYFNLGNDDQGMWAAAAMDAAEANFSPPNSTEHSWLELTQAAFNRMSGRWDSSTCGGGLRWQAFAWLNGYSYKASVSNALLFQLSSRLARFTNESVYSDWANKIWDWTTDVGFVNTTTYAVYDGADTSTNCTTLDPSQWSYNIGIFMVGAAYMYNYTGETVWRERLDGLISHATSYFFTDDIAWDPQCEYFDDCNSDQTAFKGIFMQSFGNTIRLAPYTYDTLYPLIQTSAAAAAKQCCGGYSGTSCGIYWFWNNGTWDDNYGVQEQFSALQAVQMLMIEYAPEIATLASSTDNRSNSTYASNVVINDTNTTTTIVVKEKDRGGAGFLTFLSAIFILGASIWALVEDEEGKIPSRGKKGIAISS
What are the official names of this protein?
Putative mannan endo-1,6-alpha-mannosidase C1198.06c, Endo-alpha-1->6-D-mannanase C1198.06c.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 76 family.
Protein: TRUB_DESPS
Sequence: MEEQDFTAGIFLIDKPVGITSFGVVSRVRRILGMKKVGHAGTLDPFATGLLVVCAGRPATKMISSFMDGEKEYIATLCLGVETETQDPEGAEIARKQVGFLHAETIETCLAGFKGTQMQVPPAYSALKHQGKPLYYYARKGIEVKKDAREITVHEIERLGEGDLEGDHPSLVIRVRCSKGSYIRTLGSDIGKVLGCGAHLTDLRRTKSGFFNVEDALTDVDMLAEDAHERFMKKVLSVESVGKLLQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y1749_CLOPS
Sequence: MSNNFDHTMQFDFSKNKEDLTKSILTDVYNSLKEKGYNPVNQLVGYLISGDPTYITNYNGARALVRKLERDEILEEVIKSYLEIK
What are the official names of this protein?
UPF0297 protein CPR_1749.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: IST1_PONAB
Sequence: MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKGYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGGGGFTAPVGGPEGTVPMPMPMPMPSANTPFSYPLPKGPSDFNGLPMGTYQAFPIIHPPQIPATPPSYESVDDINADKNISSAQIVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFEELKKKT
What is the function of this protein?
ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation (By similarity).  Is required for efficient abscission during cytokinesis (By similarity).  Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (By similarity).  During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (By similarity).  Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2 (By similarity).  Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (By similarity).
What are the official names of this protein?
IST1 homolog, Charged multivesicular body protein 8, CHMP8.
What is the protein family that this protein belongs to?
Belongs to the IST1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Nucleus envelope. Note=Localizes to centrosome and midbody of dividing cells. Colocalized with SPART to the ends of Flemming bodies during cytokinesis. Localizes to the reforming nuclear envelope on chromatin disks during late anaphase.
Protein: RS19_SHEPW
Sequence: MPRSLKKGPFIDLHLLKKVEKAMEAGDKKPIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTDEMIGHKLGEFSPTRTYRGHAADKKAKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SBCD_STAEQ
Sequence: MKIVHTADWHLGKILNGKQLLEDQKYILTQFKQHMEKEQPDLIVIAGDLYDTSYPSKEAIGLLEETIEYLNIELKIPIIMISGNHDGRERLNYGSKWFENNQLYIRTQLENIDDPIELSGVQFFTLPFATVSEVQNYFKDKQIETYQQALNECLEQMSSSIDNNKVNILIGHLTIEGGKTSDSERPLTIGTVESVDMHSFRLFDYVMLGHLHHPFSINNSFIKYSGSILQYSFSEVNQSKGYRVLDIENNQLLNETFVPLKPLRELEVIEGDYEDIIQERIKVKNKNNYFHFKLTNVSHITDPMMKLKQIYPNILALSNVVFDHSENFSHVEIKKQDDQTIIENFYKNMTDQHLSQVQSDKIKHLLSFILDREG
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit D.
What is the protein family that this protein belongs to?
Belongs to the SbcD family.
Protein: PURA_MAGO7
Sequence: MATIILGSQWGDEGKGKLTDILCPSAEICARSAGGHNAGHSIVAQGVSYDFHLLPSGLVNPKCMNLIGSGVVFHVPSFFSELEKLEAKGLAGVRDRIFVSDRCQVNFDLHAAVDGLEEVELGERKIGTTGRGIGPSYSTKASRSGVRISEVFDEAVFERKLRQLADGYRKRFGDLLKYDVEEEIARFKEYRKLLPNYVVDAVKFIKDAQDQNRKILIEGANALMLDIDYGTYPYVTSSNPCLGGIITGLAINPRKIETIVGVVKAYTTRVGDGIFKTEDEGEIGTKLQDIGREWGVSTGRKRRCGWLDLVVVKYSAAINHYTSLNLTKLDVLDTFPTLKVAVAYKDPATGEELDFFPADLSLLERCEVVYKEFEGWNTPTTHIKKFEELPAQARQYVEFIEQYVGVKVGWIGTGPDREDMIYR
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_PAPAN
Sequence: MAHPVQLGLQDATSPVMEELITFHDQALMAMFLISFLILYALSSTLTTKLTNTNITDAQEMETIWTILPAVILILIALPSLRILYMTDEINNPSFTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLNPGDLRLLEVDNRVVLPIEAPVRMMITSQDVLHSWTIPTLGLKTDAVPGRLNQTVFTATRPGVYYGQCSEICGANHSFMPIVAELIPLKIFEMGPVFTL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATP25_YEAST
Sequence: MNKFCLLPFHGKRIGVANIPFTILFKKGPYFLHSHITAVYYSTKGKNDSHEQSRVSKKSTFTPLETPWYLRIVDNEKELMEGKKNNHHTMNKELEIPKTSPNSLRKIADLLTGKLGLDDFLVFDLRKKSPNSVSAVNKLGDFMVICTARSTKHCHKSFLELNKFLKHEFCSSAYVEGNFNERQESRRKRRLARKSNLSKLLGRSSECSAKDLNSEAWYMIDCRVDGIFVNILTQRRRNELNLEELYAPENEKSKFQNIDSGNVPTISGVNEISSNNNILLGLRRLAQQRRRYSTINPNGLSNLRYFLQKEDFKGANKIIQSSSGTETHNIRTLEHVKNTLKDLVGQERKVDVVQWKSLFDEHSTFLTINQSAAYWPLRLEYAILLNKADPQFYSDRVFLKDYLLLKKSLGQELIREDLIALLEMVLKTQHSSHSYFNLVKQNRVIIRALNLFKGLQTEDDGSVVYDEVVISLLLNSMVADERVKLRSLYETIDHIFQTFGDKLTSGMIVSILQNLAKIKDWNKLLQVWEAITPTEGEGQDKRPWNEFINVINQSGDSHVISKIVNNGHLLWIRRLNVNVTPELCNSIKALLKTAGMENSTLEEFLVRGTNNQ
What is the function of this protein?
mRNA stabilization factor specific for the 0. 95 kb OLI1 mRNA.  Also involved in OLI1 ring formation.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial, OLI1 mRNA stabilization factor.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SEM4F_MOUSE
Sequence: MLARAERPRPGPRPPPVSLFPPPSSLLLLLLAMLSAPVCGRVPRSVPRTSLPISEADSYLTRFAAPHTYNYSALLVDPASHTLYVGARDSIFALTLPFSGEKPRRIDWMVPETHRQNCRKKGKKEDECHNFIQILAIANASHLLTCGTFAFDPKCGVIDVSSFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYTATVKNFLGTEPIISRAVGRAEDWIRTETLSSWLNAPAFVAAMVLSPAEWGDEDGDDEIFFFFTETSRVLDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASGVLQDMTELRPQPGAGTPLFYGIFSSQWEGAAISAVCAFRPQDIRAVLNGPFRELKHDCNRGLPVMDNEVPQPRPGECITNNMKFQQFGSSLSLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPETQPVESMKLYHDWLLVGSHTEVTQVNTSNCGRLQSCSECILAQDPVCAWSFRLDACVAHAGEHRGMVQDIESADVSSLCPKEPGEHPVVFEVPVATVGHVVLPCSPSSAWASCVWHQPSGVTSLTPRRDGLEVVVTPGAMGAYACECQEGGAARVVAAYSLVWGSQRGPANRAHTVVGAGLVGFFLGVLAASLTLLLIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALGKRGSGFGGFPPPFLLDSCPSPAHIRLTGAPLATCDETSI
What is the function of this protein?
Probable cell surface receptor that regulates oligodendroglial precursor cell migration (PubMed:21945643).  Might also regulate differentiation of oligodendroglial precursor cells (By similarity).  Has growth cone collapse activity against retinal ganglion-cell axons (By similarity).
What are the official names of this protein?
Semaphorin-4F, Semaphorin-W, Sema W.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic density. Perikaryon. Cell projection, dendrite. Note=Colocalizes with DLG4 at synapses.
Protein: PUTX_PSEPU
Sequence: MSKVVYVSHDGTRRELDVADGVSLMQAAVSNGIYDIVGDCGGSASCATCHVYVNEAFTDKVPAANEREIGMLECVTAELKPNSRLCCQIIMTPELDGIVVDVPDRQW
What is the function of this protein?
The oxidation of camphor by cytochrome P450-CAM requires the participation of a flavoprotein, putidaredoxin reductase, and an iron-sulfur protein, putidaredoxin, to mediate the transfer of electrons from NADH to P450 for oxygen activation.
What are the official names of this protein?
Putidaredoxin, PDX.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
Protein: AROA_STRU0
Sequence: MKLQINAGPLKGNVTVPGDKSISHRALIFGSIAEGKTEIKGLLKSQDVQRTLVALRHLGVTIEESDQKVIIQGKGFSGLTAPDSPLDMGNSGTSLRLLAGLLSGQDFPVQFFGDASLSQRPMDRIVIPLREMGARVEGQGPKHLPPITVLGSSQLTAINYQMPLASAQVKSAILLAALQTKGQTQVFEKAVTRNHTEVMIKQFGGEIFQSGKEIRIIGPQTLKGQSLTIPGDISSAAFWIVAALIIPGSAISIKNVGINPTRTGIIDLVKKMGGAIELTDRDDINQSATIHVSYSKLKGTRIAGEMIPRLIDELPIIALLATQAEGTTVVQDAQELRVKETDRIQVVTSLLRKMGADIEEKTDGFVIKGKTELHSCQADAFLDHRIGMMVAIAALLVKTGEMILNGEEAIQTSYPQFFKDLESLQHD
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VRTN_HUMAN
Sequence: MTSRNQLVQKVLQELQEAVECEGLEGLIGASLEAKQVLSSFTLPTCREGGPGLQVLEVDSVALSLYPEDAPRNMLPLVCKGEGSLLFEAASMLLWGDAGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTSLPPATLEAIFDADVKASCFPSSFSNVWHLYALASVLQRNIYSIYPMRNLKIRPYFNRVIRPRRCDHVPSTLHIMWAGQPLTSHFFRHQYFAPVVGLEEVEAEGAPGVAPALPALAPLSSPAKTLELLNREPGLSYSHLCERYSVTKSTFYRWRRQSQEHRQKVAARFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKHELLGSGTCPALPPREVLGMEELEKLPEEQVAEEELECSALAVSSPGMVLMQRAKLYLEHCISLNTLVPYRCFKRRFPGISRSTYYNWRRKALRRNPSFKPAPALSAAGTPQLASVGEGAVIPWKSEAEEGAGNATGEDPPAPGELLPLRMPLSRWQRRLRRAARRQVLSGHLPFCRFRLRYPSLSPSAFWVWKSLARGWPRGLSKLQVPVPTLGKGGQEAEEKQEKEAGRDVTAVMAPPVGASSEDVEGGPSREGALQEGATAQGQPHSGPLLSQPVVAAAGGRDGRMLVMDMIATTKFKAQAKLFLQKRFQSKSFPSYKEFSALFPLTARSTYYMWKRALYDGLTLVDG
What are the official names of this protein?
Vertnin.
What is the protein family that this protein belongs to?
Belongs to the vertnin family.
Protein: METK_ZYMMO
Sequence: MRSNYLFTSESVSEGHPDKVADQISDAIVDLYLSRDPEARVACETLVTTQRIIIGGEVRSAVPVSEEEIEKTVRETVREIGYEQTGFDWRTAEFANHLHAQSADIAQGVDAGEDKDEGAGDQGIMFGFATDETPDYMPATLYYAHRILERLAEDRHQKKVDFLEPDAKSQVTLVYENGVPVRASALVLSTQHSPALSSKEGQAKLRDYVKSVYEDVLPKGWMPDDKAIFVNPTGLFEIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYVARYLAKNIVAAGLAKKVTIQLSYAIGVSEPLSLYVDTHGTGTVDEAKIEEVLPKLIRLTPKGIRTHLKLNKPIYKPSAAYGHFGRKADGDFFPWEKLDLVDKLKAAFA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.