PharMolix/UniProtQA huggingface dataset:
Protein: GRPE_AGRFC
Sequence: MTDDTKKPGPDADVAEEFVDPAQAGEEQAETAEPDPVELLKAENADLRDKFLRLAAEMDNLRRRTERDVKDAKAYSLAGFARDMLAVSDNLRRALEAIPDELKTNGEAGLNGLIEGVEMTERSMLSTLERHGVKKIDAEGQKFDPNFHQAMFEVPNTAVPNNTVLQVIQAGFTIGDRVLRPAMVGVAKGGPKAEPSASAEPGTSSLNEKDA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_LIMF3
Sequence: MLCPHCHHNGSRVIDSRPAEDGMSIRRRRECVNCGFRFTTFERYEETPLLVVKKDGTREEFNRQKILNGLVRSAEKRPVSMDKLTKIADHVEARVRRLGENEVSSQVIGEFVMNELKPVDEIAYIRFASVYRQFKDVDAFFKEIESMKKEER
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: METK_SYNS9
Sequence: MSRYVFTSESVTEGHPDKICDQVSDAVLDALLAQDPASRVACETVVNTGLCMITGEVTSKAKVDFIHLVRDVIKEIGYSGARAGGFDANSCAVLVALDQQSPDIAQGVNEADDHAGDPLDLVGAGDQGIMFGYACNETPELMPLPISLAHRLARQLAEVRHNGTLDYLLPDGKTQVSVVYENDQPVAIDTILISTQHTAEVGGMSDEQGIRERITEDLWTHVVEPATADLNLKPSREGTKYLVNPTGKFVVGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARFVAKALVASGLAGRAEVQLSYAIGVAKPVSILVESFGTGTVSNEDLTALVQEHFDLRPGAIIENFGLRNLPQARGGRFYQNTAAYGHFGRNDLNLPWEDVAAKAEELRKA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_RHOPT
Sequence: MSITAERKAEVIKTSATKAGDTGSPEVQVAILSERITNLTAHFKTHTKDNHSRRGLLKLVSTRRSLLDYIKKKDEARYKALLEKHNIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SYL_PSYWF
Sequence: MSTTAPEQNNPNHYHPQAIEAEQQAKWAADKRFEVSNDISKDANTRYMLSMFPYPSGKLHMGHVRNYTISDVLSRYYRLKGDQVLQPMGWDAFGMPAENAAIANQVAPAKWTFSNIDNMRAQLKTLGLSIDWSREFATCTPEYYRWEQWFFLQLYKKGLVYKKLATVNWDPVDNTVLANEQVVDGKGWRSGAPVEKRDIPMYYFKITDYADELLDDLDKLEGQWPSDVITMQRNWIGRSQGMEVHFPYKNSDDISTLDVFTTRPDTLMGVTYVAVAAEHRLAKLAAEKDPKIAEFCELCKKGSVAEADLAKAEKIGMDTGLTVTHPLTGEEVPVWVANYVLMSYGSGAVMAVPAHDERDFEFANKYNLPIKTVIKTPEDHEGAYTERGTLVNSGEFDGLDFDGSFEAMLAKLEPQKLAARKIQYRLRDWGVSRQRYWGCPIPMINCEYCGNVPVDEADLPIKLPTDVVPDGRGNPLKNIPEFVNTTCPKCGGPAERETDTFDTFMESSWYYARFASPNDDTQMVEKAAADKWLPVDQYVGGVEHAVMHLLYARFYHKLMRDEGLVSGDEPFKNLLTQGMVLAGTLYRDNPEGGKTYYFADDVEISYDDRGQPTQAILKADGQPVTIGKIEKMSKSKNNGVDPQTTIDQYGADTVRLYTLFAAPADQTLEWSDDSLKGPYNFLKKVWRETQSHLEATQELGLQVANLPAASSIDASQLDSLAKGLRRKTHEVITKIDNDLGERLSLNTPVSSLMELANEIGTFISKNQQINEHTLAVQHEALVTLLTLLSVYAPHIGEHLLEKLGVDTTRLRYPEADSAALVQDTITMVVQVNGKVRGKMEVAPGTDAESLKAQAKAIESVAKYLTGDIKKEIVVPNKLVNIVVAG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C71BT_ARATH
Sequence: MAIILCFLILLPLILIFLKKLKHSKWKLPPGPPKLPFIGNLHQLQELPPRNLNHKYGPVILLRFGFVPLVVISSKEAAEEVLKIHDLECCSRPETAGTRKISYNFKDIGFAPYGEEWKAMRKLSVVELFTAKKHQYFRSIREEENDLLVKKLTELALTRSPVNLKKTLFTLVGSIVCRIGFGFNLHECEFIDENSISDLVDKSEILEMTSMFSDFFPGGIGRFIDWISGQNKRFDNVFSDLDTFFQNILDYHLKPGRKVADSSDIIDVVINMIKKQEKDGDSFKLTTDHLKGMISDIFLAGVSTSASTLIWAITELVRNRKVMKKVQEEIRTTLGDKKERITEQDLTNLHYFKLVVKEIFRLHPAVPFLLPRETLSHVKIQGYDIPAKTQIMINVYAIARDPKLWTNPDEFNPDRFLDSSIDYKGLNFELLPFGSGRRICPGMTMGITLVEFALLNLLYFFDWGLPEKEEADKIITGNGVAVGLVQVLLH
What are the official names of this protein?
Cytochrome P450 71B29.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: STT3A_CANLF
Sequence: MTKLGFLRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKAVKTGSIYWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMASTEEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDTGKHIKEHDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEAYTTEHWLVRIYKVKDLDNRGLSRT
What is the function of this protein?
Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.  This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets (By similarity).  STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient post-translational glycosylation and mediate glycosylation of sites that have been skipped by STT3A (PubMed:12887896).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A, Oligosaccharyl transferase subunit STT3A, STT3-A.
What is the protein family that this protein belongs to?
Belongs to the STT3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL29_PROM2
Sequence: MKNSESLKEFKKLNSDQITEKIDQLRKDLFDLRFKQATRQLNETHKFKIIKKQVAQLLTLSKSQSASQTTSD
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CSGG_ECOLI
Sequence: MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPAPTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQNLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFGIGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGEVGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKAERQNDILVKYRHMSVPPES
What is the function of this protein?
May be involved in the biogenesis of curli organelles.
What are the official names of this protein?
Curli production assembly/transport component CsgG.
What is the protein family that this protein belongs to?
Belongs to the CsgG family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DUT_SHV21
Sequence: MPYKVPEIYYRFEPQTFYITSPARASNLQLINHNNILVKAGQVTIVSTGIIFPKETSFAFILYGKSAKSIFCHTGLIDPGFQGELKLIVLNKTEDDITLFENDLRVSVTAFVYGVPKLHDYSDLCPPRYSKDAGFDLYLPTDVTVKPRVPNRYSVNICCPAQLKSYKPVLFGRSGLAAKGLTIKVSRWQNQLQIIFYNYTKSQITYTARTRIAQVVFMHKKHLPTTLTRLKPTMHLSENIKYSWARVSFQDIKTFPVQDEKLYSSSKDTSDSQMSRGDAGLGSSGLM
What is the function of this protein?
Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: HEM1_CHLP8
Sequence: MNIISVGVNHKTAPIEIRERIALSEVQNKEFVTDLVSSGLASEAMVVSTCNRTELYVVPGMPEVNCDYLKDYIISYKDARNAVRPEHFFNRFYCGTARHLFEVSSAIDSLVLGEGQILGQVKDAYRIAAEVGTAGILLTRLCHTAFSVAKKVKTRTKLMEGAVSVSYAAVELAQKIFSNLSMKKVLLIGAGETGELAAKHMYAKNARNIVITNRTQSKAEALAEELGTNRVLPYESYKEHLHEFDIIITAVSTKEYILNAAEMQQSMAKRRLKPVIILDLGLPRNVDPEVGALQNMFLKDIDALKHIIDKNLERRRAELPKVKSIIDEELIGFGQWINTLKVRPTIVDLQSKFIEIKEKELERYRHKVSEEELKRMEHLTDRILKKILHHPIKMLKAPVDTADNIPSKVNLVRNIFDLEEPNQSLQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: UBIG_ACIBS
Sequence: MSQLNVDLQEIAKFEALAAKWWDQHSEFRPLHQINPLRLNWIDERAGGLAGKKVLDVGCGGGILAESMARRGADVLGIDMGEAPLAVGRLHAQQENVQNIEYRQIPVEELAQEQAGQYDVVTCMEMMEHVPDPASIVKACQTLVKPGGHVFFSTINRNPKSYLFAIIGAEYVLRMLPKGTHDYHKFIRPSEMAHDIRNAGLTLKEMTGLHYNPITKRYWLAPNVDVNYMVHTIKTGV
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RECA_GEOSM
Sequence: MLDKDKAEKALDLAMSQIEKQFGKGAIMRLGNEEALPDIASIPTGSLSLDIALGVGGVPRGRVIEIFGPESSGKTTLALHVISEAQKLGGIAAFVDAEHALDIGYARKLGVKTDDLLVSQPDTGEQALEIAETLVRSGAIDVLVVDSVAALVPKAEIEGDMGDSHMGLQARLMSQALRKLTGIISKSNCCVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRMDIRKIAALKQGNDMIGSRTRVKVVKNKVAPPFKEVEFDILYGEGISKEGDILDLAVERNVVEKSGAWFSYGKERIGQGRENSRLFLKEHPEITAEIREKLVTPQQDAATPGAV
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_BIFLS
Sequence: MTDTTVEAPATPRLKVKYNEQIIPELEKEFKYSNPMQVARVQKVVVSMGVGAAARDSKLIEGAVKDLTLITGQKPKITKAKKSVAQFHLREGQAIGAYVTLRGDRMWEFLDRLLTLALPRIRDFRGINGHQFDGQGNYNFGLTEQSMFHEIDPDSIDHVRGMDITVVTSTKDDKEAYALLKHLGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: FAR7_LOBRE
Sequence: ARSDNFVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-7, FMRFa-7.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPA_SHEPW
Sequence: MINGSIVALITPMNSDGTVDNKSLENLVEYHIAQGTDGIVAVGTTGESATLPAKEHIQVVQQTVSFAAGRIPIIGGNGANATAEAIELTKGLSSVGVEAMLGVTPYYNKPSPKGLVAHYKAVAQSTDIPQILYNVPGRTSVDMLPETVAELASVSNIIGVKEATGDLSRVSKLRSLCGDDFLLYSGDDATAREFLTLGGNGIISVANNIVPKAFKAMCDAALAGNTEEAIAVEKSMQSLFSALFCEANPIPVKWAAHQMGLISKGEIRLPLTELSSEFHGLLLEAMKNARIEV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_CITUN
Sequence: MPSVYGARLTTFEDEEKESEYGYVRKVSGPVVIADGMNGAAMYELVRVGHDNLIGEIIRLEGDSATIQVYEETAGLMVNDPVLRTHKPLSVELGPGILGNIFDGIQRPLKTIAIRSGDVYIPRGVSVPALDKDTLWEFQPKKIGEGDLLTGGDLYATVFENSLMQHHVALPPDAMGKVTYVAPAGQYSLKDTVLELEFQGVKKSFTMLQAWPVRTPRPVSSKLAADTPLLTGQRVLDALFPSVLGGTCAIPGAFGCGKTVISQALSKYSNSDTVVYVGCGERGNEMAEVLMDFPQLTMTLPDGREESVMKRTTLVANTSNMPVAAREASIYTGITIAEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLAARLASFYERAGKVKCLGGPERTGSVTIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLISYSKYSTALESFYEQFDPDFINIRTKAREVLQREDDLNEIVQLVGKDALAEGDKITLETAKLLREDYLAQNAFTPYDKFCPFYKSVWMMRNIIHFYNLANQAVEKGAGMDGQKITYTLIKHRLGDLFYRLVSQKFEDPAEGEPALVAKFKKLHEDLTAGFRALEDETR
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CYMBA_MELOB
Sequence: GFPTCGETCTLGTCNTPGCTCSWPICTRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide mobo-A.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: RSMJ_PSEP1
Sequence: MEEQGTGIRVEAMAAEYAQQARVWAERLGLPLQDDTAAFAVQVGADGLQIQQLGPQAPGPVRVDFVEGQAAHRRQFGGGNGQMIAKAVGIAQGIRPQVLDATAGLGKDAFVLASLGCQMTLIERQPLIAALLEDGLARARADEEVGPIVGRMRLLTGNAIERMRAWEGEAPQVIYLDPMFPHRDKSALVKKEMRVFRPLVGDDLDAPALLEAALALASHRVVVKRPRKAPIIDGPKPSHSLEGKSSRYDIYPKKALKA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPB_DECAR
Sequence: MPQKLILASTSPYRRELLSRLGLAFDVANPQTDESPIFGESPESMALRLSEAKARAAAQAYPDALIIGSDQVATVNGNIYGKPGTHERAVKQLRELSGKTVNFFTGLCLLNARTGEAEVRGIPTLVTFRELTDSEIDNYLRREPAYNCAGSAKSEGLGIALMSSMRGDDPNALVGLPLIALCDMLRKQSLGVL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALX_PHOLL
Sequence: MNSVGSPLLWGSFAVLITIMLLLDLSLQGRKKEQAMSFRQAAVWSVIWVSLSLLFALGLWWYCRETVGVAVANSQVMAFLTGYLLEKALAVDNVFVWLMLFSYFAIPANLQRRVLIYGVLGAIVLRTVMIFAGSWLVSQFSWILYLFGLFLLVTGVKMALVKEDDSPIGDKPFVRWLKAHIRITDNLHGERFFVKEKGLLYATPLILVLILVEISDVIFAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAEKFTMLKYGLSVILAFIGIKMLIIDFYHIPIGGSLGAVASILAVTMIINVWVNKYKATENQ
What is the function of this protein?
Has been proposed to be a redox modulator.
What are the official names of this protein?
Putative membrane-bound redox modulator Alx.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARLY_SULTO
Sequence: MVLYRRWGTEKDFVSTYTSSIDSDKEIVEEVKVVMKAHVIELYLSGYITKDTAKRILLAINSFHELKEGYEDIHEALEDHIIKTVGEEGGWVGFGRSRNDHVATALRLKMRKYLIEILYDIISLRKTLIEKSKTSTEILFPTYTHFQPAQPSTLAHYFLYIEDELDTIWNYIYSSLLLVNRSPLGSGAIVGTNVKLDRKREAELLGFDDIIYNTISATSSRLDLINAVSNLSLLMLFFSRIAEDLILLSSMFINIVKLPDSHVSTSSLMPQKRNAVTLEILRSKAGECFGDLSSLFNIYKGLPSGYNLDLQEMNKHYWDCVKIVNSSIEVINSILEGIEVLNFQLDDKTTATDVAEDLAITGIPYRKAYMEVANKIRAGTFISEISPKTSIYKKAVIGSPNPELINEEIKIKENRIAEEESKLKKYEEKIIGKMNELKVIEDDLIL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_PSEPK
Sequence: MFLRHCITFTLIALLAGCAGFGSREALQGHGDPQQWRAHKAQLSSLDGWQINGKVGIRAPRDSGSGTLFWLQRQDYYDIRLAGPLGRGAARLTGRPGGVVLEVANQGRYEATSPEALLEEQLGWQLPVSHLVWWVRGLPAPDSKSKLTLDGDSRLASLDQDGWQVQYLSYTEQNGYWLPERLKLHGKDLDVTLVVKDWQPRQLGH
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: HIS6_BURCM
Sequence: MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDDQGADELTFLDITATSDQRDLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPQLVRDAADKYGSQCIVVAIDAKRVSADGETPRWEVFTHGGRKNTGLDAIEWARKMAELGAGEILLTSMDRDGTKSGFDLALTRGVSDAVPVPVIASGGVGSLQHLADGIKDGRADAVLAASIFHYGEHTVGEAKRFMSDQGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEDB_ASPTN
Sequence: MKRGGYRQINKALNISAFENYLDIQHDHLPKLNDVEQLSPRVLRVLGQNAGKFTLQGTNTYIVGTGRERLIIDTGQGIPEWTDLISSTLRDSAITLSHVLLTHWHGDHTGGVPDLIRLYPHLSNSIFKHSSSNGQQPIIDGQVFHVEGATVRAMHSPGHSHDHMCFILEEENAMFTGDNVLGHGTSAVELLGIWMASLRLMQSSGCRVGYPAHGAVIADLLAKIAGELDQKARREARVVRTLARNKREEQSKGRSKGSMTVQELVTAMHGKGLDDQVRTMALEPFINEVLGKLAGDGCVAFEVRRGEKRWFIVNDVTSSP
What is the function of this protein?
Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of geodin, an intermediate in the biosynthesis of other natural products (PubMed:7665560, PubMed:19549600, PubMed:24009710).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) gedC (PubMed:12536215, PubMed:19549600).  The atrochrysone carboxyl ACP thioesterase gedB then breaks the thioester bond and releases the atrochrysone carboxylic acid from gedC (PubMed:19549600).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodinanthrone (PubMed:24009710).  The next step is performed by the emodinanthrone oxygenase gedH that catalyzes the oxidation of emodinanthrone to emodin (PubMed:1810248).  Emodin O-methyltransferase encoded probably by gedA then catalyzes methylation of the 8-hydroxy group of emodin to form questin (PubMed:1444712).  Ring cleavage of questin by questin oxidase gedK leads to desmethylsulochrin via several intermediates including questin epoxide (PubMed:3182756).  Another methylation step probably catalyzed by methyltransferase gedG leads to the formation of sulochrin which is further converted to dihydrogeodin by the sulochrin halogenase gedL (PubMed:24009710).  Finally, the dihydrogeodin oxidase gedJ catalyzes the stereospecific phenol oxidative coupling reaction converting dihydrogeodin to geodin (PubMed:7665560).
What are the official names of this protein?
Atrochrysone carboxyl ACP thioesterase, ACTE, Geodin synthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: GLGC_AGRRK
Sequence: MVEKRFQPLARDAMAYVLAGGRGSRLKELTDRRAKPAVYFGGKTRIIDFALSNALNSGIRRIGVATQYKAHSLIRHMQRGWNFFRPERNESFDILPASQRVSETQWYEGTADAVYQNIDIIEPYGPEYMVILAGDHIYKMDYEWMLQQHVDSGAEVTIGCLEVPRMEAVGFGVMHVDEKDQIIDFVEKPADPPGIPGNPDFALASMGIYVFHTKFLIECLKRDAADPNSSRDFGKDIIPYIVKNGKAVAHRFAQSCVRSDFEREAYWRDVGTIDAYWQANIDLTAVVPELDIYDKSWPIWTYAEISPPAKFVHDDENRRGSAVSSVVAGDCIISGASLSNSLLFTGVRANSYSKLEGAVVLPSVKVGRHAQLKNVVIDHGVNIPEGLVVGEDPQLDAKRFRRTESGICLITQTMIDKLDI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: CH601_SINFN
Sequence: MAAKEVRFHTDAREKMLRGVDILANAVKVTLGPKGRNVVLDKSFGAPRITKDGVTVAKEVELEDKFENMGAQMVREVASKTSDIAGDGTTTATVLAQAIVKEGAKAVASGMNPMDLKRGIDKAVDAIVEELKTNARRVTKNDEIAQVGTISANGDIEIGRFLAEAVEKVGNEGVITVEEAKTAVTELEVVEGMQFDRGYLSPYFVTNPDKMRVELEEPYLLIHEKKLSNLQALLPVLESVVQSGKPLLIIAEDVEGEALATPVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGTAISEDLGIKLENVTLNMLGRAKKVVVEKENTTIVDGAGSKSEIQGRVAQIRAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGSTEVEVKERKDRVDDAMHATRAAVEEGVLPGGGVALLRAVKALDSIRTENADQKHGIEIVRRALEAPVRQIAENAGAEGSIIVGKLREKTEFGFGWNAQTNEFGDLYDQGVIDPVKVVRTALQDAASVAGLLITTEAMVAEKPKKDAPLPPMPGGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.