PharMolix/UniProtQA huggingface dataset:
Protein: ACSF1_NOSS1
Sequence: MVNTLPKPGIKTPSKETVLTPRFYTTDFETAANLDLSAQENELQAMLAEMRADYNRHHFVRDEAFEQSWEHIDGEARQAFIEYLERSCISEFSGFLLFKELSRKLKNRSPVLAEMFQLMARDEARHAGFLNKAMGDFKLSLDLATVTKTRTYTFFPIEWVLYTVYLSEKIGYWRYIIIFRHLEKHPENQFYPIFRYFESWCQDENRHGDIFKALLRSQPQLWNNWKARLWSRFFLLSVFATHTLTVHERSGFYKSLGLDATDFDLQVVRNTNETAGRAFPVMLNTEHPKFFPLLQRCAGYNLNISEIERSSQPKFVKLIRKLPLIAAIVWNLLMVYLIKPIDTEALRETVR
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 1, Mg-protoporphyrin IX monomethyl ester oxidative cyclase 1.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: MKTX3_MESMA
Sequence: MNYLIVISFALLLMTGVESGRDAYIAKKENCTYFCALNPYCNDLCTKNGAKSGYCQWAGRYGNACWCIDLPDKVPIRIPGPCIGR
What is the function of this protein?
This protein markedly relaxes the rat carbachol-precontracted anococcygeus muscle.  This relaxation is inhibited by the inhibitor of nitric oxide (NO) synthase, N-nitro-L-arginine methyl ester (L-NAME), suggesting that the response induced by this protein is NO-mediated (By similarity).
What are the official names of this protein?
Makatoxin-3, Makatoxin III, MKTXIII, MakatxIII, MkTx III.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NU5C_CALFG
Sequence: MEHTYQHAWIIPFAPLPFTMSIGLGLLLVPTATKNLRRMWTFPSVSLLSIAMVFSVNLSIQQINGSSIYQHLWSWTINNDFSFEFGHLIDPLTSIMSILITTVGIMVLIYSDNYMSHDQGYLRFFAYMSFSNTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPTAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFEIFTNLIHNNGVNSLFATLCAFLLFVGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFTVIPYIMNLISLIGVITLLLGATLALAQRDIKRSLAYSTMSQLGYIMLAPGIGSYRAALFHLITHAYSKALLFLGSGSIIHSMEPIVGYSPDKSQNVVLMGGLTKYLPITKTTFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIACSTAGLTAFYMVRVYLLTFDGHLHVHFQNYSGTRNSSFYSISIWGKEGTKFVNGNLPLSTLKPNKISFFSKKISNKMDGNVGNRIRSFSFRIRFDNKETFVYPHESDNTMLLPLLGLVLFTLFVGSVGIPFDQGGTEFDILSKWLNPSINLLHPNSNVSVDWYEFGTNAIYSVSIACFGIFIASLFYGSIYSSFQNLDFINSFVKKPGSKRIFLDRIINVIYNWSYNRGYIDVFYTTCFTKGIRGLAELTYLLDRRLIDGIANGIGMASFFVGEGIKYVGGGRISSYLFVYLSYVSILLLIYYFYFFSFLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYC_RAT
Sequence: MLKFQTVRGGLRLLGVRRSSTAPVASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENGVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTNSPINSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGIVDTQFIDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKVSPSPVDPIVPVVPIGPPPAGFRDILLREGPEGFARAVRNHQGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFNNLFSIENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVFKFCEVAKENGMDVFRIFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSLEYYMGLAEELVRAGTHILCIKDMAGLLKPAACTMLVSSLRDRFPDLPLHIHTHDTSGSGVAAMLACAQAGADVVDVAVDSMSGMTSQPSMGALVACTKGTPLDTEVPLERVFDYSEYWEGARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQMLGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGIPHGGFPEPFRSKVLKDLPRIEGRPGASLPPLNLKELEKDLIDRHGEEVTPEDVLSAAMYPDVFAQFKDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFELNGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDVKVAAGAKVVKGQPLCVLSAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.  Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
What are the official names of this protein?
Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase, PCB.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ORF50_HHV8P
Sequence: MAQDDKGKKLRRSCVESFVGLSDELKAQLYQCVLLINDAYETIYDPSDLNRVVEDVCIRIMKECSKLGALCGLFTDINMFNLFCFFRASRMRTKGAAGYNVPCAEASQGIIRILTERILFCTEKAFLTAACSGVSLPPAICKLLHEIYTEMKAKCLGAWRRLVCNRRPIMILTSSLLKLYNTYDTAGLLSEQSRALCLLVFQPVYLPRIMAPLEIMTKGQLAPENFYSITGSAEKRRPITTGKVTGLSYPGSGLMPESLILPILEPGLLPASMVDLSDVLAKPAVILSAPALSQFVISKPHPNMPHTVSIIPFNPSGTDPAFISTWQAASQNMVYNTSTAPLKPATGSSQTVSVKAVAQGAVITATTVPQAMPARGTGGELPVMSASTPARDQVAACFVAENTGDSPDNPSSFLTSCHPCDPNTVIVAQQFQPPQCVTLLQVTCAPSSTPPPDSTVRAPVVQLPTVVPLPASAFLPALAQPEASGEELPGGHDGDQGVPCRDSTAAATAAEATTPKRKQRSKERSSKKRKALTVPEADTTPSTTTPGTSLGSITTPQDVHATDVATSEGPSEAQPPLLSLPPPLDVDQSLFALLDEAGPETWDVGSPLSPTDDALLSSILQGLYQLDTPPPLRSPSPASFGPESPADIPSPSGGEYTQLQPVRATSATPANEVQESGTLYQLHQWRNYFRD
What is the function of this protein?
Transcription activation.
What are the official names of this protein?
Putative transcription activator ORF50.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TAF50 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: NUOB_CHESB
Sequence: MGLNDTLVAPRSRGIIDPNTGNPVGANDPFYGAINEELSDKGFLVTSSEALITWARTGSLMWMTFGLACCAVEMMHTSMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LEPA_LEPCP
Sequence: MDHIRNFSIIAHIDHGKSTLADRIIQRCGGLSDREMEAQVLDSMDIERERGITIKAQTAALQYKARDGQVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTALDLGVTVVPVLNKMDLPNADPDNAKAEIEDVIGIDADDAIPCSAKTGMGIDEILEAVIARMPPPKGNPDGPPRAMIVDSWFDNYVGVVMLVRVVDGTLGKGERIRMMATNSVYPIEHLGVFTPKSENREALKAGEVGFIICGIKELQAAKVGDTVTLEKKLPNNAGPAAEALPGFKEIQPQVFAGLYPTEASEYDQLRDALEKLKLNDSSLRYEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDQDLITTAPSVVYEVQLNGGDVIEVENPSKMPEVGKIAEIREPIVTVHLYMPQDYVGPVMTLANQKRGVQLNMAYHGRQVMLTYEMPLAEIVLDFFDKLKSVSRGYASMDYEFKEYRASDVVKVDILINGDRVDALSIIVHRAQSQYRGRAVAAKMREQIPRQMYDVAIQAAIGANIIARENIKALRKNVLAKCYGGDISRKRKLLEKQKAGKKRMKQIGSVEVPQEAFLAILQVED
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ERF19_ARATH
Sequence: MDYRESTGESQSKYKGIRRRKWGKWVSEIRVPGTRDRLWLGSFSTAEGAAVAHDVAFFCLHQPDSLESLNFPHLLNPSLVSRTSPRSIQQAASNAGMAIDAGIVHSTSVNSGCGDTTTYYENGADQVEPLNISVYDYLGGHDHV
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF019.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPA_SALTY
Sequence: MAAQGFLLIASFLLILLVLAKPLGSGLARLIAAVPLPGVAGIERILWRTLGITDHEMNWRQYLLALLTLNLLGLGILFCLLFWQEWLPLNPQRLPGLSGDLALNTAVSFVTNTNWQAYSGESTLSYFSQMAGLTVQNFLSAATGIAVVFALIRAFTRQNVHTLGNAWQDLVRITLWILFPVALIIALFFIQQGVPQNLSAYQPITTLEGAKQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNLAQMLAIFLIPAALCFAFGEAAGDRCQGRALLWAMSFIFVVCVAVVMWAEVQGNPHLLAAGADSSVNMEGKETRFGVLASSLFAVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKMTALAILVTPMLVLLGSALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKVQPASQGTLATHGALFIGLLIGTVLLVGALTFIPALALGPVAEHFSLP
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYGB_SALNS
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGNVEWFAAPRRLALKVANLAESQPDREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLKTDKGEWLLYRAHVKGESTEALVPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPQILLERGKVIADYEARKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPTQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLALDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDKLQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_XANC5
Sequence: MAKLYFYYSAMNAGKTTTLLQSAHNYRERGMRTLILTPKLDHRAGSGVVASRIGLRADGRIFERDTELQQLVERDIHNDGALHCVLVDEAQFLGRAQVWQLSEVVDRLRIPVLCYGLRTDFRGELFEGSQFLLAWADELEEIKTICHSGSKATMTVRVDAHGHAVQDGPQVEIGGNERYVSVSRAEFKKIMRGEGRIDPLQIALPLPVA
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAL1_PETHY
Sequence: MEYANENCNGHASQDICVKGHDQQLDPLNWNMAADALKGSHLDEVKRMVKEFRKPVVRLGGETLTVAQVAAIASQSGTDVTVQLSEASRAGVKASSDWVLQGMINGTDSYGVTTGFGATSHRRTKEGAALQKELIRFLNAGIFGNGTESSHTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKLLNNNITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKATGPNGELLDAVKAFQRAGIDTGFFELQPKEGLALVNGTAVGSGLASMVLFDANILAVLSEVLSAIFAEVMQGKPEFTDYLTHKLKHHPGQIEAAAIMEHILDGSSYVKEAKIVHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRAATKMIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNTRLALASIGKLMFAQFSELVNDYYNNGLPSNLTGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTAEAVDILKLMSSTYLVALCQAIDLRHLEENLKATVKNSVSLVAKKVLTIGEKGELHHSRFCEKDMLKVVDREYIFAYADDACSATYPLMQKLRQVLVDRALLNVDGEKDSSTSIFQKIKAFEEELKVVLPKEIERARSDLEQGKPAIPNRIQECRSYPLYKFVREELKANYLTGEKVQSPGEEFDKVFTAMNEGKLVDPLLNCLKEWNGAPLPLC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase 1, PhPAL1.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_CLOAB
Sequence: MKSYLAKPQEIERKWYVIDVAGKPLGRAASQIASILRGKNKPIYTPNVDTGDYVIVLNAEKVLLTGKKADQKMFRHHTLYPGGLKEMSYKDAIAKKADFVFYEAVRRMLPSGVLGRKMIKKLKVYKGEEHNNEAQKPEVLELKY
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS2_YERPB
Sequence: MATVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELTKISSRKGKILFVGTKRAASEAVKEAANNCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLEIQSQDGTFDKLTKKEALMRTRELNKLENSLGGIKDMGGLPDALFVVDADHEHIAIKEANNLGIPVFSIVDTNSDPDGVDFIIPGNDDAIRAVKLYLGAVATAVREGRSQDLAVQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: KUP_ESCF3
Sequence: MSTENKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CALRL_RAT
Sequence: MMDKKCTLCFLFLLLLNMALIAAESEEGANQTDLGVTRNKIMTAQYECYQKIMQDPIQQGEGLYCNRTWDGWLCWNDVAAGTESMQYCPDYFQDFDPSEKVTKICDQDGNWFRHPDSNRTWTNYTLCNNSTHEKVKTALNLFYLTIIGHGLSIASLIISLIIFFYFKSLSCQRITLHKNLFFSFVCNSIVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLLPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLFPWRPEGKVAEEVYDYVMHILMHYQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNGFSHSDALRSASYTVSTISDVQGYSHDCPTEHLNGKSIQDIENVALKPEKMYDLVM
What is the function of this protein?
Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOLD_LAWIP
Sequence: MAADIINGMEIRESILEELRGEVANLKRDYNVVPGLVTILVGNHPASLSYVTLKIKTAIELGFHEIQDNQSETITEEELIGIIKKYNEDPLIHGILVQLPLPSHINEGKVLHAIDPNKDVDGFHPMNLGRLVIGGNAITFLPCTPAGIQELLIRSSVETLGAEVVVIGRSNIVGRPISIMLTQKGVGGDATVTLVHTKSKNIVRHCQQADIVIAAVGVPNFVKAEWIKPGATVIDVGVNRIGFNEDTGKPILSGDVDFVNVSQVAGKITPVPGGVGPMTIAMLMRNTVRSAFFHLSL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: FTR_METFV
Sequence: MKVNGVEIEDTFAEAFDIKVSRILVTAASKRLAKIAAREATGYGTSVIGCPAEAGIDTYIPPKNTPDQRPGFTIIICNPSKKKLDHELLERVGMTILTAPTAAAFDALENAEEKVNTGFKLKFFGDGYEKEGEVQGRKVHIIPIMSGEFIVEEKFGIKSGVAGGNFFIMAETQGSALLAAEMAVDAIKSVEGVMTPFPGGIVASGSKVGSKKYDFLDASTNEKMCVTLKDEIEDSEVPEDVNGIYEIVIDGIDEESVKKAMKVGIEAACKVPGVKKISAGNYGGKLGKYKLHLHDLF
What is the function of this protein?
Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR).
What are the official names of this protein?
Formylmethanofuran--tetrahydromethanopterin formyltransferase, Ftr, H4MPT formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the FTR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_SHESA
Sequence: MARTVNCVYLNKEADGLDFQLYPGDLGKRIFDNVSKEAWGLWQKKQTMLINEKKLNMMNVDDRKFLEEQMTSFLFEGKDVEIEGFVPEKGQE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: NHAA_PASMU
Sequence: MLTPIQNFLKQEAAGGILLFIFATLAIILANTPLSYLYFDFLQTPVSVQIGAFIINKPLLMWVNDGLMAVFFMLVGMEVKRELLEGSLSSYQRAVFPAIAATGGMVVPAIVFLVFNATHPEFQEGWAIPMATDIAFALGVIALLGKRVPLALKIFLLALAIIDDLGAIVVIALFFSHDLSPQAFIFAGIAVAILITMNRLKITALSAYGIVGIILWASVLKSGVHATLAGVIIGFCIPLNGKKGERPLDDFEHTLSPWSAFAILPLFAFCNAGVSLIGMGMDNLTSTLPMGIALGLLLGKPLGIFSFCFVAVKLGIAKLSEGINFKQIFAVSVLCGIGFTMSMFLAGLAFGGESDSENVTALARLGILIGSGFSAVLGY
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DIVIB_STRGZ
Sequence: MTEKDSNVEESVLEVEQASQVELDSEQISPAEKESVLAEEKEFSTDVDIPEMTAPDDEKSAFFEQWKARHQAYLAHKDEADIQAVDEGQTEQEIPEAKKSKRVLFQGIERKTESLKSKKETGEKVQTLKVDIPSKVVWKAIPVLVTSLLLAALALYFISPTSKKKQIEVVGNERLTAEQVENYSLISPDDYNVTIALHADAYAKNIKKNSSSVETATIKFQFPATFTIHIKEYAIIGYIQQQSQWYPVLSSGEIGGEPISQDSLPEDYTTINLSDKELIKELAIELGKIDAGIRSAIQTINLPPSKVTADLLTFNMRDGNTVLVPLSEISQKVSYYTKIAAEVTVPTTIDMEVGIYRYAS
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: COBL_MOUSE
Sequence: MDAPRALAAKPPTGRKMKARAPPPPGKPAAQNVHSEQKLPHDATLGSQQSLVYMKEALQNSTLDITVVLPSGLEKQSVVSGSHAMMDLLVELCLQNHLNPSHHVLEIWSSETQQPLSFKPNTLIGSLNVHTVLLKEKVPEERVKPGLTKAPEKSVRLVVNYLRTQKAVVRVSPEVPLQNILPVICAKCEVNPEHVILLRDNVAGEELELSKSLNELGIKELYAWDNRREMFRKSSLGNDETDKEKKKFLGFFKANKRSNSKAEHLGLSGADSDEDPAKSASGGDLNGCVTTPNSPSLHSRSLTLGPSLSLGNISGVSMKSDMKKRRAPPPPSPKLLGQDKVSEKASLSSQADLQKKKRRAPAPPPPQQPPPSPVVPNRKEDKEENRKSTVGVGRQVPQKPPRGTARGPPQLVLPPPPPYPPPDTDVTEPVTFPGEGAGSETSELRPKLSLPLGPGSHCSMGGVSQVPAESEETASEDTTEDSGVMSSPSDAISLDSQQDSMRSKDKWSTDQEDGSDQDLAGTPELGPQKSPSWGKSGSGSSILRTEKATMPTNDDEDLFITGHLHQTLAELDEDLEGMEENYETDTSSLTNSVNGVSNHSLQEAIIPDSGVDDIPVTFIGEVSDEPFDSGLFSSRCNNATTFNTGSIASQRSHLSPSQTEHSQPFVRTSRKEPDPSPPSQDNRKRNQPTLANTSENENPVETDPTVTSLVSKLLIDDPKAKDKGKVHGSSHSEKTQAGHGINSLRVNPRDGKDESSNSAPPPWSHHGQALGGSYGLKYGLTTYKIVPPKSEMRCYDRDVSLSTGAIKIDELGNLVSPHMNGSRTISPPSAVVETDTPPIGKVKEFWRRNSMEKYLNGPAECTIKRAPSTTITATPEKPQQDNGMKAAFTVTTPQQQPASQEYGAHLEEERSRPQSAVSCSVKVPASNPTDITFLKPQRRTSSQYVASAIAKKMGPPKVHADVVRPHKATTEQCHEEAKLARSPPTRKDDAAPNLHSEARQHEHGTNQSSVCLPSNPGVQLPAGGHPKVEVNSTYGKSSTQDYPAAVHRNSYFLPGRSSHRDRVSVGQSCGFNEKQTTSNQKANSTSNFSQALDKAHPPPLLLAEARDSGRILMNGSARTPGNCEPPHSPKESTLTSYIILQTEEKPSSLSTDGQDADDTLPSSIFGPKKKFKPVIQRPLPKDVSLHSALMEAIHSSGGREKLRKTAEQTSEGRPKKPSYVEAESERSALLAAIRGHSGTLSLRKVSSLASEELQSFRNAALGAPGLDKPQQEDLGLPPPPALPPPPAPAPQAPSASVTVSRFSTGTPSNSVNARQALMDAIRSGTGAARLRKVPLLV
What is the function of this protein?
Plays an important role in the reorganization of the actin cytoskeleton.  Binds to and sequesters actin monomers (G actin).  Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end.  Can also mediate actin depolymerization at barbed ends and severing of actin filaments.  Promotes formation of cell ruffles.  Regulates neuron morphogenesis and increases branching of axons and dendrites.  Regulates dendrite branching in Purkinje cells.
What are the official names of this protein?
Protein cordon-bleu.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, ruffle. Cytoplasm. Note=Recruited to the cell membrane via interaction with PACSIN1 (By similarity). Colocalizes with the actin cytoskeleton. Detected throughout the neuron cell body, as well as in axons and dendrites.