PharMolix/UniProtQA huggingface dataset:
Protein: HPRK_STRP1
Sequence: MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYFDYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAAKEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIEAAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: LAN1B_RUMFL
Sequence: MNKNPIYRSEEEAKNIACGNVAAELDENSQALDAINGAGWKQTIVCTIAQGTVGCLVSYGLGNGGYCCTYTVECSKTCNK
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) only active on Gram-positive bacteria in synergy with Flvbeta peptides, which are encoded by the same operon than Flvalpha. a.  Shows antibacterial activity in synergy with Flvbeta. b, Flvbeta. c, Flvbeta. e and Flvbeta. g.  Does not show antibacterial activity when tested with Flvbeta. a, Flvbeta. d, Flvbeta. f and Flvbeta. h (By similarity).  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantibiotic Flvalpha.b.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMB_PECAS
Sequence: MINNVISPEFDENGRPMRRIRSFVRRQGRLTNGQQLALDNYWPVMGVEYQTEPVDFNALFGRDAPVVLEIGFGMGASLVTMAAQHPEQNFLGIEVHLPGVGACLASAQDVEISNLRVMCHDALEVLMKMIPDSSLSMVQLFFPDPWHKVRHNKRRIVQAPFVELVQSKLKVGGVFHMATDWEPYARHMLKVMTSVAGYRNLSDNNEYVVRPESRPLTKFEARGQRLGHGVWDLMFERIK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: VM12_CROAD
Sequence: QQNLPQRYIELVVVADRRVFMKYNSDLNIIRTRVHEIVNIINGFYRSLNIDVSLVNLEIWSGQDPLTIQSSSSNTLNSEGLWREKVLLNKKKKDNAQLLTAIEFKCETLGKAYLNSMCNPRSSVGIVKDHSPINLLVAVTMAHELGHNLGMEHDGKDCLRGASLCIMRPGLTPGRSYEFSDDSMGYYQKFLNQYKPQCILNKP
What is the function of this protein?
Has no significant hemorrhagic activity, but inactivates serpins by limited proteolysis of their reactive-site loops.
What are the official names of this protein?
Snake venom metalloproteinase adamalysin-2, SVMP, Adamalysin II, Proteinase II.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TMX1_MOUSE
Sequence: MAHLGRLMVPLAALVLLLWAVPGAHGRRNNVRVLTDENWTSLLEGEWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVKVAKVDVTEQTGLSGRFIITALPSIYHCKDGEFRRYVGPRTKKDFINFVSDKEWKNIEPISSWFGPSSVLMTMMSALFQLSVYIRTSHSYFVHDLGIPAWGSYLVFAFATVLSGLLLGLCMIFVADCLCPSKRRKPQQQYAKKTSPEFSQPLKKVEEEQEADEEDVSEEEAEDREGASKATSQSSIRQRCVGLPSATDTS
What is the function of this protein?
May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin-related transmembrane protein 1, Thioredoxin domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Predominantly found in the endoplasmic reticulum.
Protein: SYAM_HUMAN
Sequence: MAASVAAAARRLRRAIRRSPAWRGLSHRPLSSEPPAAKASAVRAAFLNFFRDRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVANSQKCVRAGGHHNDLEDVGRDLSHHTFFEMLGNWAFGGEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPKAGLDPDLETRDIWLSLGVPASRVLSFGPQENFWEMGDTGPCGPCTEIHYDLAGGVGAPQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVLQGKHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVADEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRILRRAVRFSMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLGPSDMFPAEVAWSLSLCGDLGLPLDMVELMLEEKGVQLDSAGLERLAQEEAQHRARQAEPVQKQGLWLDVHALGELQRQGVPPTDDSPKYNYSLRPSGSYEFGTCEAQVLQLYTEDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVRAGQEDVLFPVARAQVCGGFILHEAVAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLRSLDEVYPDPVRVVSVGVPVAHALDPASQAALQTSVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKAATERLSLGSRDVAEALRLSKDIGRLIEAVETAVMPQWQRRELLATVKMLQRRANTAIRKLQMGQAAKKTQELLERHSKGPLIVDTVSAESLSVLVKVVRQLCEQAPSTSVLLLSPQPMGKVLCACQVAQGAMPTFTAEAWALAVCSHMGGKAWGSRVVAQGTGSTTDLEAALSIAQTYALSQL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, mitochondrial, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: A1AT_CHLAE
Sequence: HVEDPQGDAAQKTDTSHHDQEHSTFNKITPSLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHSEILEGLNFNLTEIPEAQIHEGFQELLHTLNKPDSQLQLTTGNGLFLNKSVKVVDKFLEDVKKLYHSEAFSVNFEDTEEAKKQINNYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVEATKEEDFHVDQATTVKVPMMRRLGMFNIYHCEKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENENRRSANLHLPKLAITGTYDLKTVLGHLGITKVFSNGADLSGVTEDAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQK
What is the function of this protein?
Inhibitor of serine proteases.  Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.  Inhibits trypsin, chymotrypsin and plasminogen activator (By similarity).
What are the official names of this protein?
Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTHS_YERE8
Sequence: MTPTLSSSADVLPSLSNMSSETNLLPIQQIAPQLGLSADDLIPYGHHMAKVDISALRPSGPQGKLILVSSITPTPLGEGKTVTTIGLSQGINRLGYRGVACIRQPSLGPVFGVKGGAAGGGAAQVLPMEKLNLHLTGDIHAISAAHNLAAAALDARLYHEQRLGAVFSQQTGMPLLNIDAQQILWPRVVDHNDRALRHIQVGVGGGTHGVERHDHVEITAASELMAILALSESLHDMRQRIGRIILAHSTSGQAITADDLGVAGAMTALMKETIHPTLMQTSEQTPVLIHAGPFANIAHGNSSVLADRLGLQLADYVVTEAGFGSDMGMEKFFNIKYRQSGITPSCVVLVATLRSLKANSGVFDIKPGQPLPAEILNTNIPLLSQGCANLKWHINNAKSYGLPVVVAVNCFPDDSPEELAFLADYALSAGAIACEISEAFAKGGAGTTALAQRVIDACAHASPPVLAYPDNASLEQKIEILAQRYGAREVTFTPQARQQLDSITAAGFGHLPLCIAKTPLSISADASLKNVPHDFVLPVTACAVSAGAGFVRIYAGDIMTMPGLGTQPAYYHIDIDDEGCIRGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: OTC_BRUME
Sequence: MANDNGIKHFIDLSTVPATELRAILEDAKARKARLKAGEVERPYAGKVLAMIFEKLSTRTRVSFDVGMRQLGGETIMLTGSEMQLGRSETIADTAKVLSRYVDAIMIRTTAHERMLELAEYATVPVINALTDDTHPCQIMADVLTYEEHRGPIKGKTFAWMGDGNNVLHSLVEAAARFDFNVNIATPKGSEPKSQYIDWARANGAGIMSTTDPEKAASGADCIVTDTWVSMGQEDHARGHNVFIPYQVNANLMAKADPKALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKAILAWCLQDRGLGA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_BACCQ
Sequence: MKKHGVLNSEIAAVLASLGHTDTIVIADCGLPIPDGVKRIDLAVEIGKPSFLDVLQVVADDMAIEKVTLAEEVINNNAEVNKEIELKLIEPAFEYVSHEQFKEHTKKAKAIIRTGEATPYANVILHAGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_HAEIN
Sequence: MTALSALIEQKLQSLGTILCQSFPELSPEKIHEAIQQNSNHPELPVYQLGYAIAMSDFVEKVLQKYPHLVKQWWEKSPCFADCTAYIERLNKELANVHDETALYQTLRQFRNIEMAKLSFCQSLNLATVEEIFVQLSQLAESLIIAARDWLYHQACAEIGTPMDEQGNPQQLYILGMGKLGGFELNFSSDIDLIFTYPSQGETSVENTNARRSVDNGKFFTRLGQRLISALDEFTSDGFVYRTDMRLRPFGDSGVLVLSFSAMEQYYQDQGRDWERYAMIKGRVLGAQTKDPNVSKLKKMLRPFVYRRYIDFSVIQSLREMKGKIEREVRRRGLKDNIKLGAGGIREVEFIVQVFQLIRGGREINLQQHSLLKILPEITKLRLITEQQFHDLRESYIFLRRVENILQAINDQQTQTLPTDEIDQIRLVEACKTFTCLNENNQTIEKHYPIENWDDFYRTLQQKQEKVRAVFTQLIGDEQDESSQTDSQWQDFLEADFEDIEQTLLESSVSENNIDEVLEKLAQFKDGLNHRVIGSRGRDVLSHLMPTVLALIFEQENYRTLLPRILNIIEKISSRTTYLELLLENPRALQQVIELCAQSQLISEQLAHYPILLDELLNTEALRHPLPFTQYPAELHQYLLRLPPDDEEQLIDALRQFKQATLLKVAAADILGALPVMKVSDHLTYLAEAIIEVVVNLAWKQVSSRFGVPEHLQNNEKGFLVIGYGKLGGIELGYKSDLDLVFLYDAVESQTTGGKKVIDSNQFYLRLAQKIVSIFSINTSAGVLYEADMRLRPSGDAGLIGCSLSAFSHYQLNDAWTWEKQALVRARPVFGESSLKAKFEHIRQQVLSASRDIEQLKQDVVEMRKKMFAHLSHSKHSEFNLKTDRGGITDIEFIAQYLMLANAPKKPQLTKWSDNVRIFDDMAEAKIISQTDCDTLKQCYVDLRNTIHHLNLLGKSSVVEDSEFVKERSFIQAFWDRLFVS
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: RPPH_HELPY
Sequence: MLHKKYRPNVAAIIMSPDYPNACEVFIAERIDIEGAWQFPQGGIDEGETPLEALHRELLEEIGTNEIEILAQYPRWIAYDFPSNMEHKFYSFDGQKQRYFLVRLKHTNNIDLNKHTPEFRAYQFIHLKDLLKRIVPFKRQVYRQVIAYFKREGYL
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: DXS_DICT6
Sequence: MLLQKINSPKDLKRLSIDELKTLSAEIREIIINTVENNGGHLASNLGTVELTLALHYVFDTPEDKIIWDVGHQAYTHKLVTGRAKDFHTLRQFGGISGYIAPWESEYDHFAVGHAGTSLSAALGFAKARDLKGEKYKVIAVIGDGALTSGMALEALNQIGYLNTDLIVVLNDNEHSISPNVGAIALYLAKLRKHPLYRFFKQTTQNLLKNSSIGKGLLAFDLKLERSLKSLLLENPMFEYWGFKYFGPFDGHDIPVLISVFKGIKDNLSCPVLIHITTKKGIGHKDAEATPSKFHSIGAKIEREKKVPTYTEVFGKALVELGEKYPEIVAITAAMPEGTGLSYFAQRFPERFFDVGIAEEHAVTFAAGLAKNGLKPVVAIYSTFLQRAFDQIIHDVCLQKLPIVFVLDRAGIVSDDGPTHQGIFDLSYLRLIPNMVISAPKDESELRDLLYTAINYPGPFAIRYPKSKGVGIGLKDHFERIEIGKSEILKYGKNVLILAIGSMVYPALEAESILKTEGISPTIVNVRFLKPLDVLTLEELISSHDVIITVEENVITGGLFGAISELVNILKLNKKVLPISLPDKFIEQGNAQLLRDIYGLSGHKIAEKIISVLEDVKV
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MDHC3_ARATH
Sequence: MCNLLNIEKDPIRVLITGAAGNIGYAIAPMIARGIMLGPDQPMILHLLDIEPASSSLEAVKMELQDSAFPLLKGVIATTNVVEACKDVNIVIMIGGFPRIAGMERKDVMSKNVVIYKAQASALERYASDDCKVLVVANPANTNALILKEFAPSIPEENITCLTRLDHNRALAQLADKLSVPVSSVKNVIVWGNHSSTQYPDTNHATVSTKTGDRPLKELVTDHNWLKNEFIVEVQQRGAAVLRARKQSSAFSAAGAACDHIRDWFLGTPKGTWVSMGVCSDGSYGIPPGLVYSFPVICEKGSWKIVQGLSIDEFSREKMDDSARELAEEKDLAYSCLNV
What is the function of this protein?
Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments.
What are the official names of this protein?
Malate dehydrogenase 3, cytoplasmic, Cytosolic NAD-dependent malate dehydrogenase 3, cNAD-MDH3, Cytosolic malate dehydrogenase 3, Cytosolic MDH3.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CVCA_PEA
Sequence: MATTVKSRFPLLLFLGIIFLASVCVTYANYDEGSETRVPGQRERGRQEGEKEEKRHGEWRPSYEKEEHEEEKQKYRYQREKKEQKEVQPGRERWEREEDEEQVEEEWRGSQRREDPEERARLRHREERTKRDRRHQREGEEEERSSESQEHRNPFLFKSNKFLTLFENENGHIRRLQRFDKRSDLFENLQNYRLVEYRAKPHTIFLPQHIDADLILVVLNGKAILTVLSPNDRNSYNLERGDTIKIPAGTTSYLVNQDDEEDLRVVDFVIPVNRPGKFEAFGLSENKNQYLRGFSKNILEASLNTKYETIEKVLLEEQEKKPQQLRDRKRTQQGEERDAIIKVSREQIEELRKLAKSSSKKSLPSEFEPFNLRSHKPEYSNKFGKLFEITPEKKYPQLQDLDILVSCVEINKGALMLPHYNSRAIVVLLVNEGKGNLELLGLKNEQQEREDRKERNNEVQRYEARLSPGDVVIIPAGHPVAISASSNLNLLGFGINAKNNQRNFLSGSDDNVISQIENPVKELTFPGSSQEVNRLIKNQKQSHFASAEPEQKEEESQRKRSPLSSVLDSFY
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
Convicilin.
What is the protein family that this protein belongs to?
Belongs to the 7S seed storage protein family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Vacuole. Note=Cotyledonary membrane-bound vacuolar protein bodies.
Protein: T23O_SERP5
Sequence: MNKRELESAIVTDFSKRMSYGDYLCLDQLLDCQHPLSNPQHHDEMLFVVQHQTSELWMKLMLHELQAARILVQQDKLSHCFKILARVKQIQRLLFEQWAVLETLTPSEYVEFRDVLGNSSGFQSHQYRSIEFLLGNKNAAMLAVFSNDADKHAALKAILEAPSLYDEYLLYLSRHGLPIPQECIERDWTQPYQRNPDLLPAFKEIYDHPQKYWEAYEMAEKLVDIEESFHLWRFRHMKTVERIIGFKTGTGGSSGVSFLKKALELTFFPELLDVRTEIGA
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: RSMA_PARDP
Sequence: MSAIDGLPPLREVIARHDLRAKKQLGQNFLLDLNLTAKIARAAGDLTGCDVIEVGPGPGGLTRGLLAEGARHVLAIEKDARALPALAEIATAYPGRLEVIHGDALEIDPLAHLTPPIRIVANLPYNVGTELLIRWLTPAAWPPFWQSLTLMFQKEVAERIVAQPGGKAYGRLAVLAQWRTEARIVMTLPPEAFVPAPKVHSAVVHLTALPGPRYPADPAVLNRVVAAGFNQRRKMLRASLKGLHPEIEALLIQAGIAPTARAEEIGLEQFCALARGLAAAPR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMA_PASMU
Sequence: MQKPVKRSLKERRQQVLTVLTHMLHSERGMERMTTARIAAEVGVSEAALYRYYPSKTKMFEALIDNLEAHLFTRITQSVKNETHTAARVHNIMQMVLDFARKNPGLTRILTGHALMFEEPQLQARVAQFFDRLELQFINILQMRKLREGKGFDYEERVIAAHLVNLCEGHFMRYVRSNFRHSTQQSFEQQWRLLERLFA
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LIPA_CHLTB
Sequence: MTDSESPTPKKSIPARFPKWLRQKLPLGRVFAQTDNTIKNKGLPTVCEEASCPNRTHCWSRHTATYLALGDACTRRCGFCDIDFTRNPLPPDPEEGAKIAESAKALGLKHIVITMVSRDDLEDGGASALVHIIETLHTELPTATIEVLASDFEGNIAALHHLLDTHIAIYNHNVETVERLTPFVRHKATYRRSLMMLENAAKYLPNLMTKSGIMVGLGEQESEVKQTLKDLADHGVKIVTIGQYLRPSRRHIPVKSYVSPETFDYYRSVGESLGLFIYAGPFVRSSFNADSVFEAMRQRETSTSSLLPNKD
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FHAA_MYCTU
Sequence: MGSQKRLVQRVERKLEQTVGDAFARIFGGSIVPQEVEALLRREAADGIQSLQGNRLLAPNEYIITLGVHDFEKLGADPELKSTGFARDLADYIQEQGWQTYGDVVVRFEQSSNLHTGQFRARGTVNPDVETHPPVIDCARPQSNHAFGAEPGVAPMSDNSSYRGGQGQGRPDEYYDDRYARPQEDPRGGPDPQGGSDPRGGYPPETGGYPPQPGYPRPRHPDQGDYPEQIGYPDQGGYPEQRGYPEQRGYPDQRGYQDQGRGYPDQGQGGYPPPYEQRPPVSPGPAAGYGAPGYDQGYRQSGGYGPSPGGGQPGYGGYGEYGRGPARHEEGSYVPSGPPGPPEQRPAYPDQGGYDQGYQQGATTYGRQDYGGGADYTRYTESPRVPGYAPQGGGYAEPAGRDYDYGQSGAPDYGQPAPGGYSGYGQGGYGSAGTSVTLQLDDGSGRTYQLREGSNIIGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLADGDVIRLGHSEIIVRMH
What is the function of this protein?
Regulates cell growth and peptidoglycan synthesis by binding to MviN.  May inhibit the late stages of peptidoglycan synthesis.
What are the official names of this protein?
FHA domain-containing protein FhaA.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at the cell poles and at the septum.
Protein: CYSI_SALHS
Sequence: MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPDILASLGELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: PETD_COFAR
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMVGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: THIL_PYRAB
Sequence: MVVSMREGEIISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADDIIIDGGSLGIGKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVSDPVKVALASGEEFELLFTIPREKVEELDIDFKIIGRVEGGNGVYIKRGRKIEELEVLGWEHLAGGIDVEL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: GRCA_ECO5E
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: NS1_JDNVP
Sequence: MNNGDTNRETDSTTRPNQDIIRESSGRTSPSEQCSMVANTSRKREWSHGGRGTMASIAKESQENFQYMAEELEKMGSEFFGYVTGQSIKPSSAYISDVIILRDIQLRDQCLDVLREYGRSRRNGLFGFSEEGDHIHVIHDCSYTNRSCRDIWISQVKPFGSVQKTGKPVKFIWEFKRTDWYDVFIYFFVRKRGERAIYVRGESGKIPSNDECVRWTREFKEREMVSSSDCTDYYECEQQEHKISRRSDAGSSNGRLYEKKAYSAGKFAYIRKKTKALLRKYYVSPVSAICDVPEFRDDDLLCDPKNRDYIQAACDDFGKDLNAMSLREIYNLLTEDYNFTDEQELNPYALFISSMKYDNLENSLNIIIELLKFQCNDDEDLIVEFLTNLVNVLDRRIPKLNAFLIISPPSAGKNFFFDMIFGLLLSYGQLGQANRHNLFAFQEAPNKRVLLWNEPNYESSLTDTIKMMFGGDPYTVRVKNRMDAHVKRTPVIILTNNTVPFMYETAFSDRIIQYKWNAAPFLKDYELKPHPMTFFLLLSKYNITF
What is the function of this protein?
Multifunctional protein which displays endonuclease and helicase activities required for initiating and directing viral DNA replication.  Also plays a role in viral packaging and transactivation of several promoters.  Binds site-specifically to 2-3 approximate tandem copies within the origins of replication (Ori), unwinds this hairpin region and nicks one DNA strand thereby initiating the rolling circle replication (RCR).
What are the official names of this protein?
Initiator protein NS1, NS1, Non-structural protein 1, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the parvoviruses initiator protein NS1 family.
What are the subcellular locations of this protein?
Host nucleus.