PharMolix/UniProtQA huggingface dataset:
Protein: CTF1_SCHPO
Sequence: MSMTAGNVVFVGNIPYDVSEQQMTEIFNQVGPVKTFKLVLDPETGSGKGYGFCEFFDSETTAMAVRKLNNSELGPRKIRVEFPSNDPRRNQSYEYTERTDRYMEQQNAHESSYNSRFIPPVLHSTSSLPASQGGGMPSPAIYSSSMATNLNKNINSTSVPAYNFHNSMTSDFDSASQPHTDAYNARTFQYNKSSQNKGDYTSGTSISNPTSIPLAPSVVQVLSTFSAQELLNMLSKLQTVVHIAPEEARRLLIANPALPYAAFQAMLLMNLVDANVLQQVVVAVKNKNMHQPASATSSPPSVPQKIPSSNHKSQQANGSDQGNEGKRMALIQQLLALTPEQINALPPAQRDQILSIRRQHFRQ
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
Cleavage and termination factor 1, Transcription termination factor ctf1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DOK3_CHICK
Sequence: MERPVKDGIIYVQHCKFGKRTWRKIRAQLFAASPFGVARMEKFDARDHGTVSDISLQRCARRVIRLSDCVSVGPMGTESCPKATAAFYLTTTEKNYVLAAEQRDEWIEQLCQLAFQGKKEAEQSSSTGLQPIPMEENCLYSSWQDLTEFPVLVLRTEAAARCELHGHYVLAALPHSLTLKDAQSQQPLLTWPYPFLRKFGQDQNIFSFEAGRRSDSGEGTFTFSTPRAAELCRAVAAAIACQQQGQESPQPSAQGLSNQPWGAEAEDPQCSPTLGRAHSGSHSASYPSLNLLRFPPVEPEAPAPIVYASIARGQQPHFRPCPGQPLPEHLYENIFTAQPRPLAEEEAEEEEGRWELGCRQAPEGHSSEAAVPYPARSAPQPHTQRWAPGGSRGGAEEPSRPKPQRTLRAKLVRLLSRDGPGARDWS
What is the function of this protein?
DOK proteins are enzymatically inert adaptor or scaffolding proteins.  They provide a docking platform for the assembly of multimolecular signaling complexes.  Plays a role as negative regulator of the mobilization of calcium ions and of calcium signaling.
What are the official names of this protein?
Docking protein 3, Downstream of tyrosine kinase 3.
What is the protein family that this protein belongs to?
Belongs to the DOK family. Type A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SAND_PSYL1
Sequence: MHNHNKIANKELVVNWHITEACNYRCGYCFAKWGKQKGELIQDVASISQLMDAISGLPAVLNQMHAANFEGVRLNLVGGETFLNYRKIKEVVKQAKKRGLKLSAITNGSRINNDFINLIANNFASIGFSVDSVDNSTNLNIGRVEKNAVMNPEKIIHTIASIRAINPKIEIKVNTVVSDLNKSEDLSDFIGQVMPNKWKIFKVLPVVANHHLISEEQFTRFLRRHQRFGEIIYAEDNTEMVDSYIMIDPIGRFFQNSDFNNGYYYSRPILQVGIHQAFNEINFNANKFYSRYKRASLN
What is the function of this protein?
Expression of pVip8 in E. coli (strain MG1655) confers resistance to phages lambda, P1, SECphi8 and T7.  Prevents culture collapse upon infection with T7.  Catalyzes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP) and uridine triphosphate (UTP) to 3'-deoxy-3',4'-didehydro-UTP (ddhUTP), probably via a SAM-dependent radical mechanism.  The modified nucleotides repress transcription from T7 RNA polymerase-directed genes (possibly by acting as chain terminators), strongly suggesting these nucleotides block viral polymerase transcription.
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase, SAND, Prokaryotic viperin protein pVip8, pVip8.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Viperin family.
Protein: SY65_APLCA
Sequence: MDSLLARVKRAADADALNPAQEGVTGGPDAAGLPDVSTSSPGGGGAGDKLKEKMDEYKDKLINEIENLPIWAIVLIIAGSLLFLVCCVYCVCRRSCRKRKKKEGKKGLKGAVDLKSVQLLGNSYKEKVQPDLDELPVNMEDNEDAESTKSEVKLGKLQFSLDYDFQKGELSVNVIQAADLPGMDMSGTSDPYVKVYLLPDKKKKYETKVHRKTLNPVFNESFTFKVPYAEVGSKILTFAVYDFDRFSKHDQIGQVQVPLNSIDLGRVVEDWKDLQSPDTESEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIALLQGTKRLKKKKTTIKKNTLNPYFNESFGFEVPFEQIQKVTLIITVVDYDRIGTSEPIGRCVLGCNSSGTELRHWSDMLANPRRPIAQWHTLQEVPEKN
What is the function of this protein?
Acts as inhibitor of neurotransmitter release.  Overexpression leads to a decrease in the amplitude of the excitatory postsynaptic potential in dissected cholinergic and glutaminergic neurons while depletion with antisense oligonucleotides leads to an increase.  Overexpression of isoform 1 blocks the reversal of synaptic depression by serotonin in sensory neurons.
What are the official names of this protein?
Synaptotagmin-1, Synaptotagmin I, p65.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Synapse. Note=And vesicle-like structures.
Protein: ATPD_SALPB
Sequence: MSEFVTVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENNRLNALPDVLEQFIHLRAASEATSEVEVTSATALSEEQLSKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLMN_FRATT
Sequence: MQQDKVNLLGLNQKAIEDFFISIGEKKFHARQVFKWIHKKGVIDFDAMTDLGKNLRHKLKEKAQITIPKVVFSKASKDGTHKWLIDVGGSAVETVFILAEGRGTLCVSSQVGCTLNCSFCSTGKQGFNRNLSAAEVIAQLWIAARTLSKTDGEHDFTVTNIVMMGMGEPLMNFENVVPAMDIMMDDLAYGLSRRKVTLSTSGVVPRIYDLLEQSGVSLAVSLHAPNDMLRNEIVPINKKYNIDELLEACKLYAQKGPHKHITFEYTLIEEVNDNLSDAEELVALLKSREVPAKINLIPFNPYPGTPYKKPSNNRIHRFKEFLQHNGFVTTVRKTRGDDIDAACGQLAGDVMDKTNRKQRYLKKLGDTNAN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_BRUO2
Sequence: MSNPRHNEREVRSPRGDELNAKSWLTEAPLRMLMNNLDPDVAERPHELVVYGGIGRAARTWDDFDRIVATLKTLNDDETLLVQSGKPVGVFRTHKDAPRVLIANSNLVPHWANWDHFNELDKKGLAMYGQMTAGSWIYIGAQGIVQGTYETFVEAGRQHYGGNLKGRWILTGGLGGMGGAQPLAAVMAGACCLAVECDETRADFRLRTRYVDEKTHSLDEALAKIDAWTKAGEAKSIALIGNAAEIFPELVKRGVKPDIVTDQTSAHDPVHGYLPLGWTVAEWRAKQENDPKAVEKAARASMKVQVQAMLDFWNAGIPTVDYGNNIRQMALEEGLENAFAFPGFVPAYIRPLFCRGIGPFRWAALSGDPEDIAKTDAKVKELLPDNKHLHNWLDMAKERIAFQGLPARICWVGLGDRHRLGLAFNEMVRNGELKAPIVIGRDHLDSGSVASPNRETEAMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVICCDGTEDADRRLERVLWNDPATGVMRHADAGYDIALDWARKQGLRLPAILGN
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAB3_MOUSE
Sequence: MAQNSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYMEYHSPEDNRMNRNRLLHINLGIHSPSSYHPGDGAHLNGGRTLVHSSSDGHIDPQHTAGKQLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIFIRQTSQSSSGRQTPQNAPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSVYHSPPPSQCPSPFSSPQHQVQPPQLGHPSSHVFMPPSPSTTPPHLYQQGPPSYQKPGSHSVAYLPYTASSLPKGSMKKIEITVEPSQRPGTAITRSPSPISNQPSPRNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCAPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGNHKYQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKAEVNSMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSTNRQLQINVDCTLKEVDLLQSRGNFDPKAINNFYDHIEPGPVVPPKPSKKDSSDSCAIERKARRISVTSKAPVDIHDAQAAAADEHLSICKQSARTQPRDEDYEGAPWNCDSCTFLNHPALNRCEQCEMPRYT
What is the function of this protein?
Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF).  Acts as an adapter linking MAP3K7/TAK1 and TRAF6 to 'Lys-63'-linked polyubiquitin chains.  The RanBP2-type zinc finger (NZF) specifically recognizes Lys-63'-linked polyubiquitin chains unanchored or anchored to the substrate proteins such as RIPK1/RIP1: this acts as a scaffold to organize a large signaling complex to promote autophosphorylation of MAP3K7/TAK1, and subsequent activation of I-kappa-B-kinase (IKK) core complex by MAP3K7/TAK1.
What are the official names of this protein?
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, TAK1-binding protein 3, TAB-3, TGF-beta-activated kinase 1-binding protein 3.
Protein: NDK1_MAIZE
Sequence: MESTFIMIKPDGVQRGLIGEIISRFEKKGFYLKALKLVNVERSFAEKHYADLASKPFFQGLVDYIISGPVVAMVWEGKSVVTTGRKIIGATNPLASEPGTIRGDFAVDIGRNVIHGSDSIESANKEIALWFPEGPADWQSSQHPWIYEK
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).  Involved in transcription regulation (Probable).  Has G-quadruplex (G4) DNA-binding activity, which is independent of its nucleotide-binding and kinase activity.  Binds folded G4 with low nanomolar affinity and corresponding unfolded G-rich DNA more weakly.  Stabilizes folded G4s regardless of whether they are prefolded or not (PubMed:25679041).
What are the official names of this protein?
Nucleoside diphosphate kinase 1, Nucleoside diphosphate kinase I, NDK I, NDP kinase I, NDPK I, ZmNDPK1.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL9_SALAI
Sequence: MKIILTQEVSGLGAPGDIVEVKNGYGRNYLLPQGFAIAWTKGAEKQVTLIKRARSAREIRDLGHANEVKGQLEGLKVTLKARAGDGGRLFGSVTAAEIVAAVKAAGGPTLDRRRLELPSHIKSIGSYPVRIKLHPEVTAAFDLSVVQG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YQJH_ECOLI
Sequence: MNNTPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDGFTSRGFDDHSKLFFPQPDAHFVPPTVTEEGIVWPEGPRPPSRDYTPLYDELRHELAIDFFIHDGGVASGWAMQAQPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLETLSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYFIWITGEGKVVKNLSRRFEAEQYDPQRVRAAAYWHAK
What is the function of this protein?
Plays a role in iron homeostasis under excess nickel conditions.
What are the official names of this protein?
NADPH-dependent ferric-chelate reductase, Ferric siderophore reductase.
What is the protein family that this protein belongs to?
Belongs to the SIP oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAPB_ECOLI
Sequence: MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVNFLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLTYEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAVEENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRAKESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL
What is the function of this protein?
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis.  May act by modulating the proteolytic activity of FtsH towards LpxC.  May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.
What are the official names of this protein?
Lipopolysaccharide assembly protein B, Lipopolysaccharide regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the LapB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: NCB2A_DROVI
Sequence: MTTSIELSSYRDQHYKGSRFEQERSLRDSSTLYVGNLSFYTAEEQIHELFSRCGDVRMIVMGLDKYKKTPCGFCFVEYYKRSEAEAAMRFVNGTRLDDRLIRVDWDAGFIEGRQYGRGKTGGQVRDEYRTDYDAARGGYGKLLTQKIAPNPDNR
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2-A, 20 kDa nuclear cap-binding protein A, NCBP 20 kDa subunit A, CBP20-A.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YD025_YEAST
Sequence: MLMILWFFNQIARCRVNFTGGDGYKPIILYHVIH
What are the official names of this protein?
Putative uncharacterized protein YDL025W-A.
Protein: MTOX_ECOK1
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQMLWDELSRHNEDDPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: ATP23_LODEL
Sequence: MSSSTQPAQTSPSPSKITLSADSQLNGFEWWRRSLQYQTGLGLTPSEKAQYEYDYFHRNLDQKCDTCNDHLKWVLAYSPSVRFMMDHIQKLNKSNEPVPRNKIVCQTCDFTKGGGFDPNHGIVLCSNYIRSKWQLEDILAHELVHVYDYMKFNVNMLDLRQHACTEIRASMLSGECRVWNEMKKTGMGNFGKKFQECIRRRAVLSVEANPVCKSREEAEKAVDVVWKSCFNDTRPFERVYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: CAMT_MYCTU
Sequence: MGMDQQPNPPDVDAFLDSTLVGDDPALAAALAASDAAELPRIAVSAQQGKFLCLLAGAIQARRVLEIGTLGGFSTIWLARGAGPQGRVVTLEYQPKHAEVARVNLQRAGVADRVEVVVGPALDTLPTLAGGPFDLVFIDADKENNVAYIQWAIRLARRGAVIVVDNVIRGGGILAESDDADAVAARRTLQMMGEHPGLDATAIQTVGRKGWDGFALALVR
What is the function of this protein?
Catechol O-methyltransferase that can use various catechol-like compounds such as gallic acid (GA), 3,4-dihydroxy-5-methoxy-benzoic acid (5OMeBA), protocatechuic acid (PCA), 3,4-dihydroxy-benzaldehyde (DHA), dopamine, caffeic acid (CA), luteolin, quercetin, and 5-hydroxyuridine.
What are the official names of this protein?
Catechol O-methyltransferase, COMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: PYRI_METM5
Sequence: MKMELKVKPIENGTVIDHISGSKALKVYKILNIEEKLPITLALNVPSKKGVMKDILKIEGLELTKDDVNKIALISPDATINIIKEGKVIKKFKVDLPKRIDGIIKCTNPNCITNKENIEGKFSIEQKNTLKIRCEYCEKFINSIIISK
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: GA45B_MOUSE
Sequence: MTLEELVASDNAVQKMQAVTAAVEQLLVAAQRQDRLTVGVYEAAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDIDIVRVSGMQRLAQLLGEPAETLGTTEARDLHCLLVTNCHTDSWKSQGLVEVASYCEESRGNNQWVPYISLEER
What is the function of this protein?
Involved in the regulation of growth and apoptosis.  Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK (By similarity).
What are the official names of this protein?
Growth arrest and DNA damage-inducible protein GADD45 beta, Myeloid differentiation primary response protein MyD118, Negative growth regulatory protein MyD118.
What is the protein family that this protein belongs to?
Belongs to the GADD45 family.
Protein: METK2_PETCR
Sequence: AGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARRCIVQVSYAIGVPEPLSVFVDSYGTGKIPDREILQIVKETFDFRPGMISINLDLKRGGNGRFLKTAAYGHFGREDPDFTWEVVKPLKWEKA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I85A4
Sequence: MEAKLFVLFCAFTTLEADTICVGYHANNSTDTVDTILEKNVTVTHSVNLLENSHNGKLCSLNGVAPLQLGKCNVAGWILGNPECDLLLTANSWSYIIETSDSENGTCYPGEFIDYEELREQLSSVSSFERFEIFPKANSWPNHETTKGITAACSYSGTLSFYRNLLWIVKRGNSYPKLSKSYTNNKGKEVLIIWGVHHPPTTSDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVKGQAGRMNYYWTLLDQGDTITFEATGNLIAPWYAFALNKGSGSGIITSDTPVHNCDTKCQTPHGALNSSLPFQNVHPITIGECPKYVKSTKLRMATGLRNVPSIQSRGLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQIAIDGISNKVNSVIEKMNTQFTAVGKEFNDLEKRIENLNKKVDDGFLDVWTYNAELLVLLENERTLDFHDFNVRNLYEKVKSQLRNNAKEIGNGCFEFYHKCDDECMESVKNGTYNYPKYSEESKLNREEIDGVKLESMEVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RK23_THAPS
Sequence: MVNSLDMNVIKYPIITDKATRLLANNQYSFIVSPKSDKPTIKAAIEYLFNVKVVKINTAHLPKKKKRIGQYLGWKAHYKKAIVTLSEGDTINLFAEEN
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL333_STAAM
Sequence: MRKIPLNCEACGNRNYNVPKQEGSATRLTLKKYCPKCNAHTIHKESK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: STC2_RAT
Sequence: MCAERLGQFVTLALVFATLDPARGTDSTNPPEGPQDRGSQQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIQGLHGICMTFLHNAGKFDAQGKSFIKDALRCKAHALRHKFGCISRKCPAIREMVYQLQRECYLKHDLCSAAQENVVVIVEMIHFKDLLLHEPYVDLVNLLLTCGEDVREAVTRSVQAQCEQSWGGLCSILSFCTSNIQRPPTAAPEHQPLADRAQLSRPYHRDTDHHLTANRGAKGERGSKSHLHAHARGGAGGQSAQGPSGSSEWEDEQSEYSDIRR
What is the function of this protein?
Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
What are the official names of this protein?
Stanniocalcin-2, STC-2.
What is the protein family that this protein belongs to?
Belongs to the stanniocalcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAD_THESM
Sequence: MNILIFGPPGSGKSTHSRRIIEKYNLEYIASGDIIRAEINKGNALGREMKKYIEKGDLLPDTVINTLVLSRLRKKRENFIIDGYPRTAEQVLALENFLYDHGIRIKLAIDIFISKEESITRISGRRICRQCGAVYHIKYNPSKVPGKCDICGGEVIQREDDTPEIVSRRYDIYINNMEPIIKFYKGQGVYVQINGHGGIEEVWERIRPLLDYIWNREKKKEEFE
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_AZOC5
Sequence: MTIRRLPPVLIDRIAAGEVVERPAAAVKELVENAIDAGATEIEVLVVGGGREMIRISDNGSGMSADELSLAVERHATSKLPTEDLLAISTLGFRGEALPSIGAVARLSIASRPKSAPHAFEIRVEGGVVTPPRPAALNGGTRVEVRDLFFATPARLKFLKSDRAEAAAAADVVRRLALARPDVAFTLMTDDRQPLTWVARSMDEAGRAARVADVLGAEAGRNLIPVVGERGGVRLVGLAGLPTYSKANSLSQFLFVNGRPVRDKLLMGALRAAYSDLLPSDRYPVLALFLSLDPREVDVNVHPAKTEVRFRDGGNVRALLVRTLTDALAARVPSTAGTIADRLVELARTPELEPARPAAAIPEFRPYRAEPMPAGGYDWRASPARPLNVAEPDGALEAEMESFAEAVQASFDVGMPAADARADAAVPETGDLDRPLGAARAQLHETYIVAQTREGMVLVDQHAAHERLVYEKLKAALERDGVARQGLLVPAVVDLDPAEADRLAERAGDLAALGLVIEPFGIGAVLVREVPALLAKADVTKLVRDVAEHSAEWDDALPLERRLLHVAATMACHGSVRAGRRLRVEEMNALLREMEETPNAGECNHGRPTFITLSLKDVEKLFARR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: YIDD_CHLTR
Sequence: MQTSRISSFFRGLVHLYRWAISPFLGAPCRFFPTCSEYALVALKKHPLRKSLFLIAKRLLKCGPWCIGGIDLVPRTSVEEYLSSPTPLAESPDDRTVPHTQETS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.