PharMolix/UniProtQA huggingface dataset:
Protein: UPP_SALAR
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RL7_XYLFM
Sequence: MSLTNEKIVEAIAEKSIMEVMELVKAIEDRFGVSAAAPVMVSGSAAAAAPVEEQTEFTVTLKEAGAKKVEVIKAVRAVTGLGLKEAKDLTEAGGILKEAVSKEEAEKIKKELEAAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: URK_BACSU
Sequence: MGKNPVVIGIAGGSGSGKTSVTRSIYEQFKGHSILMIQQDLYYKDQSHLPFEERLNTNYDHPLAFDNDYLIEHIQDLLNYRPIEKPIYDYKLHTRSEETVHVEPKDVIILEGILVLEDKRLRDLMDIKLYVDTDADLRIIRRIMRDINERGRSIDSVIEQYVSVVRPMHNQFVEPTKRYADIIIPEGGQNHVAIDLMVTKIQTILEQNAIL
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCC1_MOUSE
Sequence: MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLSGVQPPGLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSVKGEFGVEDDRAARGPLPPKSEEASGSESGVSSSSGDGPSAGSEMDKRVHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDANKKAEEERGRLEGDLKVLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAADQVEGFELQTKQLTREVEELKGELQTIRDEKNRPDPRLQELQQEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALESQISEVSELLGTYEKAKQKDQLAIQKLKERLLQLDLENKTLALAASSRSSLDIHGDESSLDINVLKDKMEKLKKLLQVAARKSQVTLDVEKLCDPEIMANSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGSLGKELEAAQEQLAELKDKYISLRLSCEELESQHQQEAEDWKQELARLQQLHRQELERSQLDFRDRTLKLEEELHKQRDRALAVLAEKDLELEQLRSVALSSGLPGRRSPVGGVGGGGLGDPADTASSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEVEAHQLQERLLEEGERHREEVGALQSHIEKNMRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVLMRLPSGGSWWPSGKR
What is the function of this protein?
Probably involved in maintaining Golgi structure.
What are the official names of this protein?
GRIP and coiled-coil domain-containing protein 1, Golgi coiled-coil protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein.
Protein: MDTH_YERPP
Sequence: MALVSQARSLGKYFLLFDNLLVVLGFFVVFPLISIRFVDQLGWAALVVGLALGLRQLVQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFALMAMADEPWILWLACALSGLGGTLFDPPRTALVIKLTRPHERGRFYSLLMMQDSAGAVIGALIGSWLLQYDFHFVCWTGAAIFVLAAGWNAWLLPAYRISTVRAPMKEGLMRVLRDRRFVTYVLTLTGYYMLAVQVMLMLPIVVNELAGSPAAVKWMYAIEAALSLTLLYPLARWSEKRFSLEQRLMAGLLIMTLSLFPIGMITHLQTLFMFICFFYMGSILAEPARETLGASLADSRARGSYMGFSRLGLALGGALGYTGGGWMYDTGKTLDMPELPWFLLGIIGLITLAGLYWQFNRRRIESAMLSSS
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RGS18_HUMAN
Sequence: METTLLFFSQINMCESKEKTFFKLIHGSGKEETSKEAKIRAKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQRPTNLRRRSRSFTCNEFQDVQSDVAIWL
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.
What are the official names of this protein?
Regulator of G-protein signaling 18, RGS18.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_BURCJ
Sequence: MAKVLVLYYSSYGHVETMAQHIVEGAKSVPGVEVTLKRVPETIPVDQARAIGVKVDQAAPVATVDELADYDAIIFGTPTRFGNMAGQMRTFLDQTGGLWMKGALVGKIGSVFASTGTQHGGQETTITSFHTTLLHHGMVIVGVPYACSGLVNMNEITGGTPYGATTLAGADGSRQPSANELDIARYQGKHVAELANKLAS
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: MTNA_HUMAN
Sequence: MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRDGTLDGPQM
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).  Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, Mediator of RhoA-dependent invasion, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
Protein: LIPK_MOUSE
Sequence: MWWLLATTCCVLLSGPIDGYKQESITNPEANMNISELISYWGYPYEKHDVITEDGYILGTYRIPHGKGCSRKTAPKAVVYLQHGLIASANNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQYWAFSWDEMAKYDLPATVNLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRLFFALAPVATVKYTRSPMKKLTTLSRKAVKVLFGDKMFSTHTWFEQFIATKVCNRKLFHQLCSNFLFSLSGFDPQNLNMSRLDVYLSQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGQDVVADAKDTKNLLPKIANLIYYKEIPHYNHMDFYLGQDAPQEVYGDLIRMIEESLQN
What is the function of this protein?
Plays a highly specific role in the last step of keratinocyte differentiation.  May have an essential function in lipid metabolism of the most differentiated epidermal layers (By similarity).
What are the official names of this protein?
Lipase member K, Lipase-like abhydrolase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL29_SODGM
Sequence: MKANELREKSAEELNTELLNLLREQFNLRMQASSGQLQQTHLLKQVRRNVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: FLAD1_XENLA
Sequence: MTSTSPCLATNVPPVTAGIIIIGDEILKGHTQDTNSFFMCKKLRSIGVQVNKISVIPDDIDIIAGEIAGFSSRYTYVLTSGGIGPTHDDVTFEGVAKAFGEKTFPHPELVSLVQTFFGKSESWCPEMKLAQIPVSSRLNYGTDKRTGDCFKYPLVSVGNVYVFPGIPSLLEKSLEGLDHLFRNDKTHFHYREICVSADEVAIAGVLGEVNGRFRKHVSLGSYPDWSNNYFRVLLVLDSHSEAHLEEAHKFLIEHLPPGVVVPFVKDPVTQAAAQVYQLAHSGSPLGDKVAAALKTLEEALDTYSLEKICVAFNGGKDCTALLHLFHATVQRKFPDQKDKLQALYIRIVSPFPEMEQFMQSTTKRYNLQIYTIQGYIKQALVELKVEQPNLEAVLMGTRRSDPYSRTLTPMCLTDPDWPKYMRVNPLLDWSYRDIWDFLRTLFIPYCILYDKGYTSLGSMENTVKNPALRFTTPAGAESYHPAYKLQNEEEERVSRK
What is the function of this protein?
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FAD pyrophosphorylase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL26_TETTS
Sequence: MKTHVEVSSARRKQRKAHFASPSHLRQTLMSAHLSKDLRSKYNVRSMPVRKDDEVLIVRGKFKGNKGKVTQVYRKKWAIHVEKISKNKLNGAPYQIPLSASQLVLTKLKLDKSRQSLLTRKAASLKTKGQKHTVA
What are the official names of this protein?
60S ribosomal protein L26.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: HXT2_YEAST
Sequence: MSEFATSRVESGSQQTSIHSTPIVQKLETDESPIQTKSEYTNAELPAKPIAAYWTVICLCLMIAFGGFVFGWDTGTISGFVNQTDFKRRFGQMKSDGTYYLSDVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIVIQIASSDKWYQYFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTKDYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAKSNKVTIEDPSIVAEMDTIMANVETERLAGNASWGELFSNKGAILPRVIMGIMIQSLQQLTGNNYFFYYGTTIFNAVGMKDSFQTSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSASMAICFVIFSTVGVTSLYPNGKDQPSSKAAGNVMIVFTCLFIFFFAISWAPIAYVIVAESYPLRVKNRAMAIAVGANWIWGFLIGFFTPFITSAIGFSYGYVFMGCLVFSFFYVFFFVCETKGLTLEEVNEMYVEGVKPWKSGSWISKEKRVSEE
What is the function of this protein?
High-affinity glucose transporter.  Is only indispensable for growth on low glucose-containing media, because S. cerevisiae possesses other sugar transporters.
What are the official names of this protein?
High-affinity glucose transporter HXT2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HUTG_BORBR
Sequence: MSVANDSASIWTARDDSGERGDTRRLAHIVALGQDAGAGDAAVLGFACDAGVARNQGRRGAALAPRAIRRMMAGLPAHNLRRLVDAGDVVCEDDQLEAAQDALAGRVAALLQAGAHPVVLGGGHEIAWGSFQGLRRWLDARGDREPVLVLNLDAHFDLRTGRPGSSGTPFDQIAEYCAARGHALQYACLGVSPLGNTPALYARAAEVGAVWVEDRHMQEAHLGERLAQLDALLAAAGHVYLTIDLDVLPAATAPGVSAPAPYGVPLAVVEEVAMHVRASGKLRLADLAECNPAYDIDHRTARVAARLAWRLLGGAAR
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: RS10_CHLPD
Sequence: MAAQQKIRIKLKSYDHSLVDKWALRIIDVVKQTDAIIFGPIPLPTKAHVYTVNRSPHVDKKSREQFSFSSHKRLIEIINPTSRTIDMLMKLELPSGVDVEIKS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RSMG_TREPA
Sequence: MVTPSQHALLAEGVAHLTDARTAPALCALLKQYLEELILFNTRAHLVHVTHTEELITHHLLDSLSAWPHFTNARAIADIGSGAGLPGIPLACALALYAPETELTLIERREKRIAFLENACARLALPHLRIVHADAHDLTPYTYDAITFRALCPLNHPTVYMLLNKLRPGGVILAYKGKRKLIEQETRDFLPQSCSVFPLHVPFLHEARHLVAIHTPCAAPPQ
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase, Glucose-inhibited division protein B.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_SHEPA
Sequence: MAKKNAKNSKNSSASIARNKRATFDYKFEEKLEAGLSLMGWEVKSIRMGKVNLSESYVFLREGEAYLFGCTIAPLNTASSHVVCDPLRSRKLLLKRKELDKLQGLVDRKGYSIVPISMYWQKGAWVKIEIGLGKGKKEHDKRDDTKDREWQIEKARTIKKAVQQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RECA_CITBB
Sequence: MLDKDKAEKALDLAMSQIEKQFGKGAIMRLGNEEALPDIASIPTGSLSLDIALGVGGVPRGRVIEIFGPESSGKTTLALHVISEAQKLGGIAAFVDAEHALDIGYARKLGVKTDDLLVSQPDTGEQALEIAETLVRSGAIDVLVVDSVAALVPKAEIEGDMGDSHMGLQARLMSQALRKLTGIISKSNCCVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRMDIRKIAALKQGNDMIGSRTRVKVVKNKVAPPFKEVEFDILYGEGISKEGDILDLAVERNVVEKSGAWFSYGKERIGQGRENSRLFLKEHPEITAEIREKLVNPQQDAATPGAA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP26C_HUMAN
Sequence: MGTALDIKIKRANKVYHAGEVLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKFPSGKTEIPFEFPLHLKGNKVLYETYHGVFVNIQYTLRCDMKRSLLAKDLTKTCEFIVHSAPQKGKFTPSPVDFTITPETLQNVKERALLPKFLLRGHLNSTNCVITQPLTGELVVESSEAAIRSVELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLSVPIYMVFPRLFTCPTLETTNFKVEFEVNIVVLLHPDHLITENFPLKLCRI
What is the function of this protein?
(Microbial infection) The heterotrimeric retriever complex, in collaboration with the CCC complex, mediates the exit of human papillomavirus to the cell surface.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 26C, Down syndrome critical region protein 3, Down syndrome critical region protein A.
What is the protein family that this protein belongs to?
Belongs to the VPS26 family.
What are the subcellular locations of this protein?
Endosome.
Protein: RP1_MOUSE
Sequence: MSDTPSTSFSMIHLTSEGQVPSPRHSNITHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKTFDALLDSLSRKVPLPFGVRNISTPRGRHSITRLEELEDGKSYVCSHNKKVLPVDLDKARRRPRPWLSSRSISTHVQLCPATANMSTMAPGMLRAPRRLVVFRNGDPKNKHVVLLSRRITQSFEAFLQYLTQVMQCPVAKLYATDGRKVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLPAKLPGISHRVHQKGKAKIEKRKMSTHMPSDLRPQTDSLISEKTYDCFSDFSVAPENYLALETHESQSLSTYPSEDDVEKSIVFNQDGTMTVVMKVRFKIKEEETVKWTTTVNRAGLSNNDEKNKKSSYPGKTDYGPSSLKLEACSLPEDIVDTTQQGSLTEEENTQMTEQQALSCSSASWENASMETDIQESQKQVKHFYRPPTPGPRRMRQKKSVIGTVTVVSETEVQEKQFSYSEERKGGEKSEYHMFTHSCSKMSSVSNKLVQIGSDNEMESALERTRESGSLKSQAINAGAIEITSQKVLKMCHNNALPSTAPENSVVEEGTDNSAVSGTATIKHFRTCGNANDSFSSITADSTPTSVNNYSNDRNISELPSVGSPVLTMRLVNEFAHCGLTEKPENRKKVLSSSASKKKKKKSQQRMITSNDKKKVIETKGPPNIAGKIPRAGTTAQERLLQESDCPDKGGRVCEQGLNISPMAIESNNFFPKSNPTFSKNFYKNKLNTFQNPKTQKLLAKRKSRPRKIVSTERLRKQEIGQEDKILLHSDSKLCESHLEKQSLFHVFNILEEDQKVLHRPPFQVEKVARNLKGMAKKSLVPKVNDLHIMLRNQKKQMGVKLKSGAEVSEQHVTTRADPLASLKKPDFPEGIPHHSGKSYVKRWLQNINSYPDFEHRKSGPLCQNRSDVVNYNRNGFLGNNLHTTSSKGNGFLMESNKSKTKNDNWSGNTNQETGKSLVAKDNGEELNKHHCESQNGSLYDSYLVSLHDNCTLSQTTINEPSTKSHLSIEKSRPEVKLVYQEMNFATKRQSIEVAIQVDTMGENVLKDYLPALLLRHLEAFVPNNQKHQNGISQIPGSLAEVVFPSVIDNSSTNLLLAWLLVLNLKRTMNSFCQSDAHKMTNRPSETAALLEVLKHVAITEEADDLKAAVANLMESTKTCSGSSGREQDMLPVNCTASSLHSVDECNENGSAQKTLLDEGYSVMGDCTSEMVSKSCNSSCEMHMVSKTNPPKQVDDQSDGLLTSNSCTVSQRSTGACFLTDGVYSHEACAQKEGVYEGACLSDETHIPIRDCHTIHSVHSKENKCTDDLESTEELKTVDKVPKGLSILADSMYKNDSNVSTFQNVNKLSSQRTLLSKTYLDSDKDYSPLEEFQNCPRKKIVNKKKSISSDKEESRTSEEPRSITNSMTSSERNAISELESFEELESQDTSIFNMNVRAEKKSTKETMQKQSEARMSSELINVSGRKIIEQERRNTAILETTARGQVTPPSLAFCYDSNKNTEKEISEGETKMRVKKMVDSMENESYSESSLNFKKHHRSPGTLDWSDYGSDSESGYPCKASSNSHNDDSGQEKEPTRGIVKRAIEKLYGKAEIIKPPFFHGSIHKSQVCPYNSVEVQCAKKTNFYESECQSLVSSEQVSRSSLIFQEFPQVDANGMGDSFGDSSIENVTKSSAHDRVFTEKENGKLIDNGKWLLRENHLWRVSSDNPGMYGNADTTSVDTLIDKNSIEVPYSHFGELAPGPTMAELSSSEIEEMTQPLEVKCNYFNFPHGSDSEPFGEDFPDAQNKTCPKEKIPNHHTEEKGNYPSERLCTSVTQAFVSAGNKVHPVCSDAIKTQPLPGSNITHGALQEGDSLDKLYALCGQHCPILTVIIQPVNEESRGFAYRKDSDIENSLDFQLWMKIYPFMPQSKKHVFRSDGRNVSVGEEFAGNVIGDLCDQLYFKSMIDLVDQRANSLGKEINLKKFQLYLKKSFSDPLSTSLLVVENRNSVSLSPSSWTDNFKSIDENNNFLNRLPNSSKNPNQVVRENTNFQFHLELFGQVYLLDICQVEKPLNIKTRSKLEMYYILEGEVLFIWEEEK
What is the function of this protein?
Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors.  Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme.
What are the official names of this protein?
Oxygen-regulated protein 1, Retinitis pigmentosa RP1 protein homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, photoreceptor outer segment. Note=Specifically localized in the connecting cilia of rod and cone photoreceptors.
Protein: TATC_ORYSJ
Sequence: MGSAGALLSHSPPGLGGFPPRHHHHHRLSVLRCVPLLPSPAPEPLSCRHGRHLRCAAVDGGAGRETERPSPPAPQREESPSGSLGAALEDPSPQPVQNGSFGGITEDEEQSSLYNFLYPSKELLPDDKEMSIFDHLEELRDRIFVSVLAVGAAILGCFAYSKDLIRILEAPVSVQGVRFLQLSPGEFFFTTLKVSGYCGLLLGSPVILYEIIAFVLPGLTRDERKFLGPIVLGSSVLFYLGIFFSYTVLAPAALNFFVNYADGAVESLWSIDQYFEFVLVLLFSTGLSFQVPVIQLLLGQVGLVSSDQMLSIWRYVVVGAVVAAAVLTPSTDPLTQMLLAGPLLGLYLGGAWMVKLTGR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane.  Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation.  TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation (By similarity).
What are the official names of this protein?
Sec-independent protein translocase protein TATC, chloroplastic, Protein TWIN-ARGININE TRANSLOCATION C, OsTATC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=The N- terminus is located in the stroma.
Protein: RNFH_SHIB3
Sequence: MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: ILVC_ACTSZ
Sequence: MSNYFNTLNLREKLDQLGRCRFMDRSEFSDGCNFLKGKKIVIVGCGAQGLNQGLNMRDSGLDISYALRKAAIEEKRPSFQRATENGFKVGTYEELIPTADLVINLTPDKQHSKVVSDVMPLMKQGAAFGYSHGFNIVEVGEQIREDITVVMSAPKCPGTEVREEYKRGFGVPTLIAVHPANDPKGEGMAIAKAWASATGGDRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSIVCYDKLIADGKDPAYAGKLIQYGWETITEALKQGGITLMMDRLSNAAKLRAFELSEQIKEKLGFLYLKHMDDIISGEFSRVMMEDWANGDKDLLAWREATGKTAFENAPKADGIKISEQEYFDNGVLMVAMVKAGVEMAFDAMVASGIYEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSNVATPILAKEIIPALQKGDLGEPTPAVDIDNVTLRDVNDEIRNHPVELIGLELRGYMTDMKRISSQG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CYSH_MYCTO
Sequence: MSGETTRLTEPQLRELAARGAAELDGATATDMLRWTDETFGDIGGAGGGVSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIGTRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDVQEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTECGLHAS
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_COXBU
Sequence: MNNIIQLLETEQTQGKEIPDFRAGDTVTVQVKVKEGNRERLQAFEGVVIARRHRGLNSSFTVRKVSHGEGVERVFQLYSPLIASIKVNRRGDVRRAKLYYLRNLRGRKAKIKEKI
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: TM237_CAEEL
Sequence: MPPTSRPVPPPPKRRISESSSSSDDELTGNNSFRENQQRRFRENNEVGNISDSDNDEVFSHQESQSVGFIETDEERQREEHAQNSNLRNRRVSYGKIPVPPMSMTVEDIQEAAKHSREDPSGETVEVRRPNDPRRSSVSLDVFKSFRDPHDKRNMPAKDKTIYVEGPNGKFREMKKGKFWNRDKFDSPKKDAEKKQDEDSVIPFLLKAPGQAYRTQRVYNQIANIIQGFLAGISVMLAIFSFNLEPEVLLTGYRYMSLPIHAGFMVAFTVGLVSAIDRTGIYEVEHFTSRTRLTATVYNNGLITFIVWFVGLVSTLLCIQLESQLAFAPTRIPSEDLVHHWRVFNVLRALTSGLGFLLLAFKPDSDTMAKELREAIYEQLELVTSDPERRRVIITAMKI
What is the function of this protein?
Component of the transition zone in primary cilia.  Required for ciliogenesis.
What are the official names of this protein?
Transmembrane protein 237 homolog, Joubert syndrome 14 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM237 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes the transition zone.
Protein: ATPA_DESHD
Sequence: MNLRPEEISSIIKQQIERYDSAVEVVDVGTVIQVGDGIARVHGLEKAMSGELLEFPGGIYGMAMNLEEDNIGCIILGKFTEIREGDQVKRTGRIVEVPVGEAMIGRVVNALGQPIDGKGEIKTDKFRPIENIAPGVVYRKSVHEPLQTGLKSIDAIVPIGRGQRELIIGDRQTGKTAVAVDTIINQKGKDVICIYVAVGQKASTVAGVVKTLADHGAMDYSIVVSATASEPAPMLYIAPYSGCAMGEEFMYNGKHVLIIYDDLTKQAAAYRELSLLLKRPPGREAYPGDVFYLHSRLLERAAKLSPDLGSGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNAGFRPAINVGISVSRVGGSAQIKAMKQVAGQLRLDLAQYRELAAFAQFGSDLDKITQMRLTRGERMMEILKQKQYEPMVVEEQVVVLYAAVKGFLDDIPVDKIKSFEEEYLRTMRTTKADLLAKIRTEKALNDELNAEIEKAITEVKEGFLG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EF1B_DROME
Sequence: MAFGDVTTPQGLKELNAFLADNSYISGYTPSKADLSVFDALGKAPSADNVNVARWYRHIASFEAAERAAWSGTPLPQLAGGKPTVAAAAKPAADDDDDVDLFGSDDEEDEEAERIKQERVAAYAAKKSKKPALIAKSSVLLDVKPWDDETDMKEMENNVRTIEMDGLLWGASKLVPVGYGINKLQIMCVIEDDKVSIDLLQEKIEEFEDFVQSVDIAAFNKI
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Probable elongation factor 1-beta, EF-1-beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.