PharMolix/UniProtQA huggingface dataset:
Protein: VF137_ASFB7
Sequence: MEAVLTKLDQEEKKALQNFHRCAWEETKNIINDFLEIPEERCTYKFNSYTKKMELLFTPEFHTAWHEVPECREFILNFLRLISGHRVVLKGPTFVFTKETKNLGIPSTINVDFQANIENMDDLQKGNLIGKMNIKEG
What is the function of this protein?
Plays a role in the inhibition of the host innate immune response.  Mechanistically, promotes the autophagy-mediated lysosomal degradation of host TBK1 and affects IRF3 nuclear translocation to block type I IFN production.
What are the official names of this protein?
Structural protein A137R, Structural protein p11.5.
What is the protein family that this protein belongs to?
Belongs to the asfivirus A137R family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: LPXC_PSEPW
Sequence: MIRQRTLKNTIRATGVGLHSGEKVYLTLKPAPVDTGIVFRRADLDPVVEIPARAANVGETTMSTTLVNGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLEEQDAAKKFIRILREVTVEEGDKRATFLPFEGFKVSFEIDFDHPVLKGQTQSAVVDFSSTSFVKEVSRARTFGFMRDIEYLRKHNLALGGSVENAIVVDETGVLNEDGLRSEDEFVKHKILDAIGDLYLLGNSLIGEFKGYKSGHALNNQLLRKLIAETDAWEVVTFEDASTAPISYMRPVAAV
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: VM1V1_AGKPL
Sequence: MIQVLLVTICLAAFPYQGSSIILESGNVNDYEIVYPRKVTPVPRGAVQPKYEDAMQYELKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISTCNGLKGHFKLQGEMYLIEPLELSDSEAHAVYKYENVEKEDEAPKMCGVTQNWESYEPTKKAFQLNLTPEQQGFPQRYVELVIIADHRMYMKYKRDSNKITQWVHQMVNTINEIYRPLNIQFALVGLEIWSNQDLITVTSVSDDTLISFANWRETVLLRRKSHDNAQLLTAIVFDEGIIGRAPLAGMCDPNRSVGTVQDHSKINFRVAIIMAHEIGHNLGMGHDDNSCTCGGYSCIMLPRLSKQPSKLFSDCSKKDYLTFLKVKNPQCILNKPLRTDTVSTPVSGNELLEA
What is the function of this protein?
This venom zinc protease has fibrinolytic activity.  The recombinant enzyme cleaves both alpha- (FGA) and beta-chains (FGB) of fibrinogen, but not the gamma-chain.  The recombinant protein does not produce hemorrhage in mice and does not have effect on ADP- or collagen-stimulated platelet aggregation.
What are the official names of this protein?
Snake venom metalloproteinase VMP1, AplVMP-I, AplVMP1, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC_VIBCM
Sequence: MSKAKTLYEKIYDAHVVVAAPGETPILYIDRHLVHEVTSPQAFDGLREKGRPVRQVSKTFATMDHNVSTTTKDINASGEMARIQMQTLSKNCEEFGVTLYDINHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAKTMKIEVRGKVAPGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAIRDLSMEGRMTVCNMAIELGAKAGLIAPDATTFNYIKGRKFAPQGSDWDAAVDYWQTLKTDEDAQFDAVVTLEASEIKPQVTWGTNPGQVIAVDEPIPSPSQFADPVERSSAEKALAYMGLEAGKMLSDYKVDKVFVGSCTNSRIEDMRAAAAVAKGKKVASHVQALIVPGSEQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLGPGERCASTSNRNFEGRQGRDGRTHLVSPAMAAAAAIAGHFVDIRQF
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: GB_HCMVM
Sequence: MESRIWCLVVCVNLCIVCLGAAVSSSSTRGTSATHSHHSSHTTSAAHSRSGSVSQRVTSSQTVSHGVNETIYNTTLKYGDVVGVNTTKYPYRVCSMAQGTDLIRFERNIVCTSMKPINEDLDEGIMVVYKRNIVAHTFKVRVYQKVLTFRRSYAYIHTTYLLGSNTEYVAPPMWEIHHINSHSQCYSSYSRVIAGTVFVAYHRDSYENKTMQLMPDDYSNTHSTRYVTVKDQWHSRGSTWLYRETCNLNCMVTITTARSKYPYHFFATSTGDVVDISPFYNGTNRNASYFGENADKFFIFPNYTIVSDFGRPNSALETHRLVAFLERADSVISWDIQDEKNVTCQLTFWEASERTIRSEAEDSYHFSSAKMTATFLSKKQEVNMSDSALDCVRDEAINKLQQIFNTSYNQTYEKYGNVSVFETTGGLVVFWQGIKQKSLVELERLANRSSLNLTHNRTKRSTDGNNATHLSNMESVHNLVYAQLQFTYDTLRGYINRALAQIAEAWCVDQRRTLEVFKELSKINPSAILSAIYNKPIAARFMGDVLGLASCVTINQTSVKVLRDMNVKESPGRCYSRPVVIFNFANSSYVQYGQLGEDNEILLGNHRTEECQLPSLKIFIAGNSAYEYVDYLFKRMIDLSSISTVDSMIALDIDPLENTDFRVLELYSQKELRSSNVFDLEEIMREFNSYKQRVKYVEDKVVDPLPPYLKGLDDLMSGLGAAGKAVGVAIGAVGGAVASVVEGVATFLKNPFGAFTIILVAIAVVIITYLIYTRQRRLCTQPLQNLFPYLVSADGTTVTSGSTKDTSLQAPPSYEESVYNSGRKGPGPPSSDASTAAPPYTNEQAYQMLLALARLDAEQRAQQNGTDSLDGRTGTQDKGQKPNLLDRLRHRKNGYRHLKDSDEEENV
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: GBLP_SOYBN
Sequence: MAEGLVLKGTMRAHTDVVTAIATPIDNSDMIVTASRDRSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLAAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIQDGDAHSDWVSCVRFSPSTLQPTIVSASWDRTVKVWNLTNCKLRNTLAGHNGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKRLYSLDAGSIIHALCFSPSRYWLCAATEQSIKIWDLESKSIVEDLKVDLKTEADATSGGGNANKKKVIYCTSLNWSADGSTLFSGYTDGVARVWAIGRY
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-like protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
Protein: UBIB_XANCP
Sequence: MKAILRASRIGRVILRYRLDALLEGTPAERWLRLAKPFVPRASAEIAAQSRGARLRLALQELGPIFVKFGQILSTRRDLIPPDVAEELTLLQDRVKPFDGEAARLIVERALGLPVSVAFAAFDTTPLASASIAQVHAATLPPDANGLRREVVVKVLRPDIERQIDADIALLHSLATLVERTHPRADKIRPREVVAEIEGTLSAELDLQREGANASVLRRFWEGSDDLYVPEVIWSHTAERALTLERVYGIPSDDVAKLDAAGIDRKALAAKGVRVFYTQVFRDNFFHADAHAGNIWVDSDPERRLNPRFIALDFGIMGQLSQEDQYYLAENFMAIFHKDYRRMAELHVEAGWMPSNVRIDELEAAARSVCEPYFTRPLSEISLAEVLIKLFRVAQRYELTLQPQLILLQKTLLNIEGVGRQLDPKLDIWAVARPVLERILRERYSPRRVLGELRKRLPEIMTHAPDMPRLVHSWLKQQVEGRHQLDIRSSELRALDLSLRKLQTRVVTAITGSGLLVVAAVLYGLHPDGWYLGTVPVWSWISGGAGSAALLIAWLRR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGK_PSESM
Sequence: MTVLKMTDLDLQGKRVLIREDLNVPIKDGVVSSDARILASLPTIRLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVAEYLSKALGRDVPLVADYLDGVDVKAGDIVLFENVRFNKGEKKNADELAQKYAALCDVFVMDAFGTAHRAEGSTHGVAKYAKVAAAGPLLAAELEALGKALGAPAQPMAAIVAGSKVSTKLDVLNSLSAICDQLIVGGGIANTFLAAAGHKVGKSLYEPDLLDTARAIAAKVSVPLPTDVVVAKEFAESATATVKLIADVADDDMILDIGPQTAAHFAELLKSSGTILWNGPVGVFEFDQFGEGTKTLAKAIAESKAFSIAGGGDTLAAIDKYGVADQISYISTGGGAFLEFVEGKVLPAVEMLEQRARA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y302_ENCCU
Sequence: MKSISSYLSFAHMNITHTTEQHAENQPHWKTILDIAPFVSITFPAIMCLIFDEDSFEESPFLRFITLLLPFSYSAVQYALLYTNWKSHNKPEPILHTTLYYTLSLLLLAFTIISILSIIPFSLNEWDHAASFFYPIVLPSFTVPPAYLLSSSYFLVPRQIRLTDTVISILISVCSIVNVLLVFKEFNYYPYSAIISSISVLLQLLSEKHCLFKQSPPSTASSRAAVLILTLILAVLVYTFLGYGAIYILDDHFHLLGKMKSILPSEPHQ
What are the official names of this protein?
UPF0328 protein ECU03_0020.
What is the protein family that this protein belongs to?
Belongs to the UPF0328 family.
Protein: VKTK2_DABRR
Sequence: MSSGGLLLLLGLLTLWAELTPISGHDRPTFCNLAPESGRCRAHLRRIYYNLESNKCEVFFYGGCGGNDNNFSTWDECRHTCVGK
What is the function of this protein?
Serine protease inhibitor that inhibits plasmin (90%) (Ki=0. 19 nM), trypsin (70%), FXIa/F11 (37%) (Ki=6 nM) and FXa/F10 (20%), and prolonges the activated partial thromboplastin time.  This antifibrinolytic property has been confirmed by a fibrin plate assay.  Shows less antifibrinolytic activity that aprotinin.  In vivo, reduces the bleeding time in a murine bleeding model, and prevents the increase of fibrin(ogen) degradation products in coagulation-stimulated mice.
What are the official names of this protein?
Kunitz-type serine protease inhibitor DrKIn-II, Daboia russelii Kunitz Inhibitor-II.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: TV381_HUMAN
Sequence: MTRVSLLWAVVVSTCLESGMAQTVTQSQPEMSVQEAETVTLSCTYDTSENNYYLFWYKQPPSRQMILVIRQEAYKQQNATENRFSVNFQKAAKSFSLKISDSQLGDTAMYFCAFMK
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 38-1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: YEEX_ECOSE
Sequence: METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGEMKNGEAK
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: BTBDH_MOUSE
Sequence: MLRKGSCKPGSWGSFWAILALVGLVTRAAQRADVGGEAAGTAINHSHMLLQRLQDLLRQGNASDVILRVQAVGTDEVRAFHTHRLLLGLHSELFRELLSNQSEVMLRESRDCAAVFDKFIRYLYCGELTVLLAQAIPLHRLATKYRVASLQRGVADYMRAHLAGGVGPAVGWYHYAVSTGDEALRESCLQFLAWNLSAVAGSAEWGAVSPELLAQLLQRSDLVLQDELELFHALEAWLGRARPPPTVAERALRAIRYPMIPPAQLFQLQARSAALARHGPAVADLLLQAYQFHAASPLHYAKFFHVNGSAFLPRNYLAPAWGAPWVINNPARDDRSTSFQTQLGPSGHDAGRRITWNVLFSPRWLPVSLRPVYADAAGTALPAARPEDGRPRLVVTPASSGGDAAGVSFQKTVLVGARHQGRLLVRHAYSFHQSSEEAGDFLAHADLQRRNSEYLVENALHLHLIVKPVYHTLIRTPS
What are the official names of this protein?
BTB/POZ domain-containing protein 17, Galectin-3-binding protein-like.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTU_RICRS
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTSLTAAITIVLAKTGGAQATAYDQIDAAPEEKERGITISTAHVEYETKNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPAMVVFLNKIDMVDDPDLLELVEMEVRELLSKYGFPGDEIPIIKGSALQALEGKPEGEKAINELMDAVDSYIPQPVRATDKPFLMPIEDVFSISGRGTVVTGRVESGIIKVGEEIEIVGLKDTQKTTCTGVEMFRKLLDEGQAGDNVGILLRGTKREEVERGQVLAKPGSIKPHDKFEAEVYVLSKEEGGRHTPFTNDYRPQFYFRTTDVTGTIKLPADKQMVMPGDNATFTVELIKPIAMQEGLKFSIREGGRTVGAGVVTKINN
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_HAEIE
Sequence: MRLCDTDIERYLDDGIISLTPRPNNDKINGATIDVRLGNSFRVFREHSAPFIDLSGPKEEVSAQLESVMSDEILIPEGEAFFLHPGTLALATTLESVKLPANIIGWLDGRSSLARLGLMVHVTAHRIDPGWEGKIVLEFYNSGKLPLALRPNMVIGALSFEVLSGEAKRPYSSRKDAKYKNQQSAVASRIDEDKE
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PAN2_DROME
Sequence: MDYVYCGTDPIGASEDILSVYDAGSAPGNGHFSPSFNGFNIGTTDPEYVELVPVLADGGEHFGVSSVAFDDYEELLWMGNQGGHVTSYYTNSMQKYTSFQVHATDIVRDISTLDSGVLALTQTSLRHQIRRGLPKFTFKSNNMKEMVSMLQLSPHRLVMAGLQDELIDFDLRTLKETRIEHVGAGGCTVLRKNSRYLFAGDQLGTVTLRDLNSLSVQHTIKTHTNILSDFSVQGNLLISCGYSGRQNNLAIDRFLMVYDLRMLRLIAPIQVMIDPQMLKFLPSLTSQLAVVSSYGQVQLVDTVELSEPRVSMYQINTNGSQCLSFDISSSSQAMAFGDQSGHINMIAAVQTPQPQFNLYSRSTEFADVVPQLPMVSITDTNFPLSSVMLPHLTTGTQWFSDWPEELLRYRYHRPKTIDPEVLSNMKMQGPIGYSPNPRTARRNQIPYVIEQGGVCSPNGNGTAAATKAENGVKIIPRRYRKVELKYTKLGTQDFDFDQHNQTCFAGLEATLPNSYCNAMLQILYFTDALRVKLLEHSCIKEFCLSCELGFLFNMLDKSTASSPCQASNFLRSFRTVPEASALGLILTDRSSNVNLISLIQNWNRFILHQMHYEIFDSSKNASTYSGSVQTSTNAENAGSSETSGSSDLYDSISDENSKEDDRERSKINAETDISKIFGTKQICINRCIKCQEEKIKESILLACNLSYPNHIKDSDQYFNFGTILKRSLSSEKSIQAFCERCKKFSPTNQSVKVTSLPQILSINCGLNNEKDITFLKRQLNRCSEKTTVDAAASLSTSKPCRYGANCSRSDCHFMHPDRKSPSHTSQPNAVNNSPNGRQKSWFPLTFTMGINDQGEVQVQTQSDASSGKSEQEEETEKPPTKGLDNNRMYALHAVVCQVDDGTQKNLVSLINVQRPYHTMKLAESADDPQSQWYIFNDFSISPVSPQESVWFTLDWKVPCILFYRHVEDDSESASTTSSTVTESEETIPSESSSGSPTNLSNPFLEEIVSPMLGNLSADATLQPLQSDEMPQSGDLVAMDAEFVTLNPEENEIRPDGKTATIKPCHMSVARISCIRGQGPAEGVPFMDDYISTQEKVVDYLTQFSGIKPGDLDANFSKKRLTALKYSYQKLKYLVDVGVIFVGHGLKNDFRVINIYVPSEQIIDTVHLFHMPHHRMVSLRFLAWHFLGTKIQSETHDSIEDARTTLQLYKHYLKLQEEKKFANALKNLYERGKQLQWKVPED
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP).  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Nucleus. Note=Shuttles between nucleus and cytoplasm.
Protein: IRAD_SALPA
Sequence: MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCVVPGGETLPPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRYEPSINMLEVSVKDAHHQTLALSLEAMLQDEPEPLRLEIAYSNGRWR
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB2_RHIE6
Sequence: MGTVNNAIRDSVLFTTADSIINWSRSSALWPETFGIACCAIEMISAGCARYDLDRFGVVFRPSPRQSDVMIIAGTVTRKFAPVVRRLYDQMPEPRWVIAMGTCAISGGVYNTYAVVQGSETFVPVDVHVPGCPPRPEALMHGFLLLQEKIKRSRALAGTPLDRVIAS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNAJ_RHIL3
Sequence: MAKADFYETLGVAKSADEKELKSAFRKLAMKYHPDKNPDDKDAERKFKEINEAYEMLKDPQKRAAYDRYGHAAFEHGGMGGGGGGFAGGGFSDIFEDIFGEMMGGGRARQRSSGGRERGADLRYNMEITLEESFSGKTAQIRVPTSITCDVCSGSGAKPGTQPKNCGTCQGTGRVRAAQGFFSIERTCPTCHGRGQIIPDPCPKCHGQGRVTEERSLSVNIPAGIEDGTRIRLQGEGEAGARGGPAGDLYIFLSVKPHEFYQRDGADLYCAVPISMTTAALGGTFDVATLDGTKSRVTVPEGTQVGKQFRLKGKGMPVLRSVQTGDLYIQIQIETPQKLTKRQRELLQEFEQLSSKENNPESTGFFARMKEFFEG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_ACAM1
Sequence: MLERAEVDKVAHLARLSLTDAESEQFTTQLGDILDYFEQLSELDVAEVEPTTRAIDVSNVTRVDHLTPYDDRESILACAPDQEDEYFKVPKIMGES
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: M1_I96A2
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTESAFGLICATCEQIADSQHKSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRAIGTHPSSSTGLKNDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: FSL7_GIBZE
Sequence: MSQPCKDSDAKLRAACDRCHELKIRCTRTGGTESRCDRCEKNDIDCVYRAHRRIGRPKSQKSRCGPNTTARQNDTTTRGRIQQEQQEQMDISPPENRDSINSDFDFSIFEASGAVEWHRSSDVINVSTHQVSSTHPPFISPDCSLSHESSMSQTGSGSPFSMLNIGTMPVCDLDLSTLHGYGPSTDLVRSINHRSGSENESMEGNAELQSTQSASGSPQEEDQMLEDRLLRHQAKLRCLYSTVDATRNLISTTNDTVSHGAPLDKVLEAIMELVEILQTNANHTSSSSSSNSTTVDGPSEIRNQSRSRQDIANFNDIAILHVSISYAYIVKILAPIILSLEKSSVPVGSTSSSTYNDTTAHPSSASLPSQTGGPTKPRTVSVSLGSFSLASKPALNAQILLGMISRMLDQLHDATQPILMQVRHHHVPTQPVALQEREHHDAAMTREQHVSTGHGPDRHTSPVLSSAQAAVDSIRNEEKELLAKLNKVGNSTSATW
What is the function of this protein?
Transcription regulator that specifically up-regulates the gene cluster that mediates the biosynthesis of fusarielins F, G and H, decaketide compounds with 5 methylations and a decaline core that act as mycoestrogens as they stimulate growth of MCF-7 breast cancer cells (PubMed:22252016).  Probably binds the 5'-CGGNNNCCG-3' motif present in the promoter of all the cluster genes (PubMed:22252016).
What are the official names of this protein?
Fusarielin biosynthesis cluster transcription factor FSL7, Fusarielin biosynthesis cluster protein 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHEB2_XANOM
Sequence: MTLETPVRVLIVDDSAVVRQMLTEILSRDAGIEVVGSAADPLLAREKIKRLNPDVITLDVEMPRMDGLVFLENLMRLRPTPVVMISSLTERGADTTLQALSLGAVDFVSKPKIDVARGLEGYAEEIVSKVKMAAKAKVSALHRPSAPKVTLDMQSAPMPGSALRFRTTDRLVAIGASAGGTEALRVVLEHMPADAPAVVMTQHLPASFSTAFAERLNRHSAMSVREATDGEAILPGHAYLPPGGQHLRIIRDGARWRCRIDDGPPVNRHKPAVDVLFRSVAANAGANAVGAILTGMGDDGARGLLEMLQAGAPTLVQDEASSVVWGMPGAAYKLGAAQEVVPLDRVAERLLALSAQAR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_PSEAE
Sequence: MTTPSKFRDIEIRAPRGTTLTAKSWLTEAPLRMLMNNLDPEVAENPRELVVYGGIGRAARNWECYDRIVETLKQLNDDETLLVQSGKPVGVFKTHANAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYDGNLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLRSRYVDEQAKDLDDALARIQRYTAEGKAISIALLGNAAEILPELVRRGVRPDMVTDQTSAHDPLNGYLPAGWSWEEYRDRAQTDPAAVVKAAKQSMAVHVRAMLAFQQQGVPTFDYGNNIRQMAKEEGVANAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPQDIYKTDAKVKQLIPDDAHLHRWLDMARERISFQGLPARICWVGLGLRAKLGLAFNEMVRTGELSAPIVIGRDHLDSGSVASPNRETEAMQDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGSDEAAERIARVLTNDPGTGVMRHADAGYQVAIDCAKEQGLNLPMITAQR
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.