PharMolix/UniProtQA huggingface dataset:
Protein: ULAG_ECOSE
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_EXIS2
Sequence: MNGPDTKIPQATAKRLPLYYRFIQSLYNSGKLRVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVQHLLTFFRKTLNQDEVTNVALIGVGHLGTAFANYNFLKNNSTRIVIAFDADEDKVGTTTQDVPIYHVSDMKEQIKANHVDVAILTVPSQFAQSVADELVEYGVTGILNFTPARLNVPAHVRVHHIDLSIELQSLVYFMKHYSQSAEGVKS
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHBP_SALPB
Sequence: MDTLTAIGRWLAKQHVVTWCVHHEGELWCANAFYLFDAQNVALYLLTDDKTRHAQMSGACAPVAGTVNGQPKTVARIRGVQFKGEIRRLEGQESDAARKAYLRRFPVARVLPAPVWEIRLDEIKFTDNTLGFGKKLHWLRDSRAQQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: CARB_PSELT
Sequence: MPKRDDIEKVLVIGSGPITIGQAAEFDYSGAQAIKALKSLGYRVVVINSNSATIMTDPEFSDAVYIEPLTIDFLEAVIEKERPDALLPTLGGQTALNLAVELFKKGVLCKYDVELIGVKPDTIEKAEDREQFKTAMKNCGLEVLESRLVSSVTEAMDVVREFGYPVVIRPSFTLGGSGGGIAYNLQELKAIVENGLIESPAHTVLIEKSVIGWKEYELEVMKDHEDNFIVVCSIENFDPMGIHTGDSVTVAPAQTLTDVEYQCMRNAARKALSAIGFDAGGCNIQFAVDTYTGKLVIIEMNPRVSRSSALASKATGYPIAKISALLAVGLRLDEIPNSITEQTTAAFEPSIDYVVVKMPRFQMEKFPGAEQKLGTQMKSVGEVMSIGRTFKEALGKAVRSLELDIAPKLDLRNMREHLANPTSERMSYIFAAFRNSLSVDEVHELTFINKWFLTEIEEIMNFEKVLRKKKPKDFGSLKKAKEFGFSDRELAEIYKVQEEEIRKIRHKLGVTPVYKMVDTCSAEFEAKTPYFYSTYNGMENETIPSKRRKIMVLGSGPNRIGQGIEFDYANVHAVWAFQEEGYEVIMVNSNPETVSTDYDISDKLYFEPLTTEDILEIAKIENPDGIVVSFGGQTPLRIARALEKEGLKILAANYELIDLTESRDRFAKFLKQSGLSVPPFSVARSIKEALRAAELIGFPVLIRPSYVLGGRAMAIVDHKKDLLSYISNASLISPDHPLIIDKFLENAVELDVDVISDGENVWIAGLMEQIEKAGIHSGDSACVLPPVSLSDDLIEKIEHLIYRLIKSLKIIGPANIQLAVKDDKVYVIELNLRASRTIPFVSKAIGIPVAKIAAKTIIGKKLSQLLLRYWPYSTKERLVKYEPARSGVLPTPWPEYYSVKEAIIPFNKFSGVDILLGPEMRSTGEVMGIGDDFAEAFAKAQLSADGISTKSLLVTVNDRDKREIVPLVSYLYDLGFEVFATAGTGKILRSMGIAVKNVFKVGEGKPDVVDLIRQGKIGFIVITQSPNRKTSAEINREAENSFADDERTAGYKIRTAAIQCKVPCITTIEAFRAEVSAIRRLKKSTLSVRSLQDIFYAQQNTLLKK
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: PSTB_SACS2
Sequence: MEAGKSAEDVFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDIFQIDAIKLRKEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKYVIGRIS
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL29_NATPD
Sequence: MAILHVDEIRDMTAAEREVELEQLETELLNEKAVLAAGGAPENPGRIGELKRTIARVKTIQREEGDFDE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: TRPB_RHOPS
Sequence: MNQILPNSFRSGPDERGHFGIFGGRFVAETLMPLILELEKAYAEAKDDPAFRTEMDGYLKHYVGRPSPLYFAERLTEHFGGAKIYFKREDLNHTGAHKVNNVLGQIMLARRMGKQRIIAETGAGMHGVATATMCAKFGLQCVVYMGAVDVERQQPNVLRMKALGAEVRPVTSGANTLKDAMNEALRDWVTNVHDTFYCIGTVAGPHPYPMMVRDFQEVIGQEVREQILETEGRLPDSLIACIGGGSNAMGLFHPFLDDAGVVIYGVEAAGHGLSKLHAASIAGGKPGVLHGNRTYLLMDDDGQIQEAHSISAGLDYPGIGPEHAWLHDVGRVNFLSATDAEALDAFKLCCRLEGIIPALEPAHALAKVADLAPILPKDHLMVLNMSGRGDKDLASVAEHLGGKF
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RPOA_ECO24
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TORD_SHEPW
Sequence: MSAETANPVNQARSTIYQLLSSLFAKEVDHKTLHELTSTQAQAFWSQLAEEPNFKADVDVLVAELAKLNSDKALLELAADYCGLFLVGTNNSASPYASLYLTDTPVAKGDEPLLFGEQHQQMTQFLKQSQLQVQSEFPEPADHLAVILAYVAHIAMYTSNQQQLEFIRDNLTNWLATFVAKVAKVDTGKFYIALAQLTLAWVNSDLEWLTSESTS
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_SULIL
Sequence: MKIEVNKNLIKHLENLSLIQLSQNEEKMLENDITNIIKFFEKINELDLSNVEPLFHPLPQGRLRKDTPRDPLDRENALKNVKRKENGYIVGPRTYGE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: ATP6_STRCA
Sequence: MNLSFFDQFASPQLLGIPLILLSLLFPTLLLPSPNNRWINNRLSTLQLWFLQLITKQLMMPLNKAGHKWALILTSLMTFLLLINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPSISLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAGHLLIQLISTATLALLPTMPTISVLTATVLLLLTILELAVAMIQAYVFVLLLSLYLQENI
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ALLT_MANSE
Sequence: MNLTMQLAVIVAVCLCLAEGAPDVRLTRTKQQRPTRGFKNVEMMTARGFGKRDRPHPRAERDVDHQAPSARPNRGTPTFKSPTVGIARDFGKRASQYGNEEEIRVTRGTFKPNSNILIARGYGKRTQLPQIDGVYGLDNFWEMLETSPEREVQEVDEKTLESIPLDWFVNEMLNNPDFARSVVRKFIDLNQDGMLSSEELLRNF
What is the function of this protein?
Neuropeptide stimulator of juvenile hormone synthesis.  Cardioregulatory neurohormone that increases heart beat rate in the adult but not in the larva.  Inhibits active ion transport in the midgut of feeding fourth instar and day 2 fifth instar larva, but not in the midgut of pharate or wandering fifth instar larva.
What are the official names of this protein?
Allatotropin, AT.
What are the subcellular locations of this protein?
Secreted.
Protein: LGT_CHLTR
Sequence: MIHWDQSRTLLSFPRVGLHLSWYGILFSLGIFLSSFSGIKLATALCKDREEKKELRTSLENFALGALLAIIIGARLAYVLFYGGSFYFENPSEIIKIWKGGLSSHGAVISVVIWAAVFSRLHIRKLPMLSVTYICDLCGAVFGCAALLIRVGNFMNQEILGTPTSMPWGVIFPNGGGQIPRHPVQLYEGLGYLVLSCILYRLCYRGVIRLGSGYSAAGALIGVAVIRFCAEFFKTHQGAWLGEENILTIGQWLSIPMIFLGVGIIWIASKKK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IRS4_YEAS7
Sequence: MRLSFGKQRYHGGTTVTLTEQGASDSLRAAQAIFQNHSNEVSSPCPPVTVSRNPQTRLSEPSLQKSGRKQEQKKARIRTKQVPKIKTTAPNDVELSKKHRSSPAGKDNVSSTAQMAAALAHSQSKLSSDNNSSHSSALDTLKVLETPNLNGLLGIHSRSSSRNGSNESLTPGQRTPDNRSQENLLTSFSSGRRLSSSSMEPATNKDSNKALPKRRPSPPLQSSLVGSGQLHENENLSSISIDSRHSLNPDTSDVISNRSQTSLSQTINQLSLCESEPSIASSNTTTTTSNQGSGLPNLVPNYSSDMRKKKLVNKFKRKVFGSKPKHLSSQYEMDASSEELGQHEQQPSMRFKTTLRKTSVSTNAENDHASSLHEGNLRYKYNPSNDTYDVYDDTDSDSESDQNQDALTKPRKRDRIKRKIRNSANKTAHHRPIHRTRDRKFNEDKPWKSHTDITFVTDNERKRYESMWVSNRHRHLNLLSWWPSLTGDSGAINTLPEDGLILGIIVRDIWKRSNLPNSLLAEIYTKVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLPNVVEQCVWDSVDRYASTMVVPVSTLKAMAKQKRKQMKEEIKNIKKENRVVLVDHNSSS
What is the function of this protein?
With TAX4, acts as a positive regulator of INP51 activity and phosphatidylinositol 4,5-bisphosphate turnover.  Negatively regulates signaling through the cell integrity pathway, including the MAP kinase SLT2.  Seems also to be involved in rDNA silencing (By similarity).
What are the official names of this protein?
Increased rDNA silencing protein 4.
What is the protein family that this protein belongs to?
Belongs to the IRS4 family.
Protein: PLSB_SHEB2
Sequence: MPKHDSLWLKSLRWIQKHLVHTIVVPQDPFADLNLDAFRPLAYVMKTESLSDIAALSEITAKLGLPSPYEPLVANGVIAPRVVCLQGRKPLFGERAGNEPFLECFMRLLAVHKERPELDIQLVPVSLYWGRTPGKEDDTMKAAVFERENPTWLRKCLMILFLGRHNFVQFSNAVSLRYMADEHGTDMGIAHKLARVARVHFRRQRKVMTGPVLPNRQALFHSLLKSESLRKAIQEEAANKKISETQARETAIEYLDEIAADYSDSLVRIAERFLTWLWNKLYSGINIKGAEQVRQLHHDGHEIVYVPCHRSHMDYLLLSYILYYQGMVPPHIAAGINLNFWPAGPMFRRGGAFFIRRSFNGNKLYTAVFREYLDQLFAKGYSVEYFSEGGRSRTGRLLAPKTGMIAMTMNSVLRGIERPVTLVPVYLGYDHVMEVATYHKELSGKKKKKESVWQVFGAIRKLGNFGQGYVNFGEPITLQNFLNERAPNWRTELADDPEQKPSWLTPAVNVLANRVMTNINDAAAASSVTLTSLVLLATDQNALERSLLERQLDLYLTLLKKVPYTTYTSVAEGDGKHLVQQGLELNKFVVCADPLGEIVSIEASQAVSMTYYRNNIIHLFIVPSLIASCLTHNEQIPRQQVVSIVADFYPLLKAELFMGIKDVPAYVNQVLDFFIEQGLVVETDTLTVVPEHTSQLLLLASSVSETLQRYAIIFNLLANRPKMERSELESESHLLAQRLGALHGITAPEFYDKKLYGTLSVKLKELGYLADNQDKSNINRIRDQANSLLRPSVKQTIVASVTAEHTV
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GRPE_CORDI
Sequence: MSTTDNTNGDDRRPGQPEWDDEENNFEHLDATEVPAEEEALVESAGLDADTLADLEDAFDGVDASTEDPGATVGETSTLESELAERTEDLQRLSAEYANYRRRTDRERKVGVEAAKAKVLGELLPILDDLELAQKHGDLDEGPLKAFRDKLVSVVEGLGVSAFGAEGDVFDAERHEAVQDLSSGDDKVLGTVLRRGYQMNDRLLRTAMVIIADPAEDAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRFA_SALPB
Sequence: MARKTLRARRFFSLIFPFFFITSVYAEQTPESAKTVTVEAKNEMFAPQHPDQYQSWKATSEQSAREDALAEDPRLVILWAGYPFSRDYNKPRGHAYAVTDVRETLRTGAPKTAEDGPLPMACWSCKSPDVARLIQQEGEDGYFHGKWARGGPEIVNDLGCADCHNTASDDFAQGKPALTLSRPYAERAMEAIGKPFDKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDEGMKVENMEQYYDAIAFSDWTNSLSKTPMLKAQHPEYETWSAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKASLQKVVAERKQAIHDLKIKVEDQLVHAHFEAKAAWDAGATDAEMKPILNDIRHAQWRWDLAIASHGIHMHAPEEGLRMLGSAMDKAADARTKLARLLATKGITHEIPLPDISTKEKAQKAIGLNMQQINAEKQDFLKTVVPQWEDQARKNGLLSQ
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HIS7_CORDI
Sequence: MATQPRIGSISRVTSESDIRVEINLDGTGTVEIDTGVPFFDHMLTAFGVHGAFDLKVKATGDTHIDAHHTVEDTAIVLGQAIAQAVGDKRGIKRFGSFQLPMDETLCEAIVDFSGRPYFVTKGEPDYLVHSVIGSHYPTVLNEHFFESLALNAKITLHVLCRYGRDPHHITEAEFKAVARAIREAVGPDDRLTGIPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGP14_ARATH
Sequence: MEAMKMKLYVVVLVAVIAFSTVHQTVAAVDAPAPSPTSDASSFIPTFFASVAVMAFGFFF
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death (Probable).  Involved in the regulation of root hair elongation (PubMed:21248074).
What are the official names of this protein?
Arabinogalactan protein 14, AtAGP14, Arabinogalactan peptide 14, AG-peptide 14.
What is the protein family that this protein belongs to?
Belongs to the AG-peptide AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: XPT_BACAH
Sequence: MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGVRVESLAEIASLGNGTVTFVQHETAEVK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLA_BACSU
Sequence: MRINHNIAALNTLNRLSSNNSASQKNMEKLSSGLRINRAGDDAAGLAISEKMRGQIRGLEMASKNSQDGISLIQTAEGALTETHAILQRVRELVVQAGNTGTQDKATDLQSIQDEISALTDEIDGISNRTEFNGKKLLDGTYKVDTATPANQKNLVFQIGANATQQISVNIEDMGADALGIKEADGSIAALHSVNDLDVTKFADNAADTADIGFDAQLKVVDEAINQVSSQRAKLGAVQNRLEHTINNLSASGENLTAAESRIRDVDMAKEMSEFTKNNILSQASQAMLAQANQQPQNVLQLLR
What is the function of this protein?
Flagellin is the subunit which polymerizes to form the filaments of bacterial flagella.  Assembly into flagella requires FliW (PubMed:16936039).  Acts as a homeostatic autoinhibitory regulator to control its own cytoplasmic levels.  Partner switching by flagellin between FliW and CsrA provides a flagellar assembly checkpoint to tightly control the timing of flagellin synthesis.  Flagellin binds to assembly factor FliW, freeing translation regulator CsrA to repress translation of the flagellin mRNA.  When the flagellar hook is assembled flagellin is secreted, depleting intracellular flagellin, which frees FliW to interact with CsrA.  This derepresses flagellin translation and provides protein for flagellar assembly.  Once the flagellar filament is completed cytoplasmic flagellin levels rise and CsrA translation repression of flagellin reinitiates (PubMed:21895793).
What are the official names of this protein?
Flagellin, GSX1, Hag.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum. Secreted, cell wall. Note=Cell wall localization shown in PubMed:11987133.
Protein: ATP6_PSEPK
Sequence: MAAETASGYIQHHLQNLTYGQLPDGSWGFAHSAAEAKAMGFWAFHLDTLGWSVALGLIFLLIFRMAAKKATSGQPGGLQNFVEVMVDFVNGSVKDSFHGRSPVIAPLALTIFVWVFLMNAVDLIPVDWIPQLAILISGDPHIPFRAVSTTDPNATLAMAFCVFALIIFYSIKVKGLGGFIGELTLHPFGSKNIFVQILLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMFGSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEDNH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: E4PD_ECOK1
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDTTVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYAELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_SERP5
Sequence: MINDVISPEFDENGRAMRRIRSFVRRQGRLTKGQQHALDNYWPVMGVEYQAEPVDITALFGRDAPTVLEIGFGMGASLVTMAGHNPQQNFLGIEVHSPGVGACLADATEAELSNLRVMCHDAVEVLENMIPDGSLDMVQLFFPDPWHKARHNKRRIVQTPFVELVRRKLKVGGVFHMATDWQPYAEHMLEVMNGISGYRNLSSDNDYVPRPDSRPLTKFELRGQRLGHGVWDLMFERKE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ARCA_METHO
Sequence: MSVFDSKFNGIHVYSEIGELETVLVHEPGREIDYITPARLDELLFSAILESHDARKEHQSFVKIMKDRGINVVELTDLVAETYDLASKAAKEEFIETFLEETVPVLTEANKKAVRAFLLSKPTHEMVEFMMSGITKYELGVESENELIVDPMPNLYFTRDPFASVGNGVTIHFMRYIVRRRETLFARFVFRNHPKLVKTPWYYDPAMKMPIEGGDVFIYNNETLVVGVSERTDLDTITLLAKNIKANKEVEFKRIVAINVPKWTNLMHLDTWLTMLDKNKFLYSPIANDVFKFWDYDLVNGGAEPQPQLNGLPLDKLLASIINKEPVLIPIGGAGATEMEIARETNFDGTNYLAIKPGLVIGYDRNEKTNAALKAAGITVLPFHGNQLSLGMGNARCMSMPLSRKDVKW
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YZR5_CAEEL
Sequence: MKRAMDGAKNEAKKSKDTDLFGRPLKKTGSWESKDNGDLMIFTHSECEGKEKIAAFDMDGTLIKTKSGKVFPTNCQDWQLLYDSIPSDFKKLHSDGFKIVIFTNQKGIHAGKVDRNEFRKKIEAIVGKLGIPVQAFVSVAGGHYRKPCVGMWNELKLRNDEVEINEKESIFVGDAAGRIKTTSRPKKDHSYADRFFAANVGVKFQTPEEFFGKSKVDEPWGPPNFDPKNLFSEEITELEPHDAQLKSSEKEIILMVGFPGSGKSTFAKMLGHQHDYKIVNRDTIGTWQKCVAATRSYLADGKSVVIDNTSPDLESRKRYIDVAKELGVPIRCFEMNCSMEHAQHNIRFRVLTDDNAAEISSMVLRIHKGKYVEPTLSEGFSQIVKVNFRPKFEVEEHEKLYKMYLIE
What are the official names of this protein?
Uncharacterized protein F21D5.5.
Protein: RS16_BAUCH
Sequence: MVRIRLARGGAKKRPFYQIIVTDNHQARDGRFIERVGFFNPLATGQAVDLRLNMDRILYWINHGAKMSERLYALIKSAKNKSQYSSAG
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL23_HAEI8
Sequence: MSQERLLSVLRAPHISEKATNNAEKSNTVVLKVALDANKAEIAAAVAQLFEVKVDSVRTVVVKGKTKRRGNKMGRRSDWKKAYVTLAEGQNLDFVDSAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MYPT1_HUMAN
Sequence: MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSPLIESTANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK
What is the function of this protein?
Key regulator of protein phosphatase 1C (PPP1C).  Mediates binding to myosin.  As part of the PPP1C complex, involved in dephosphorylation of PLK1.  Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, Protein phosphatase myosin-binding subunit.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, stress fiber. Note=Also along actomyosin filaments.