PharMolix/UniProtQA huggingface dataset:
Protein: PROA_BORBR
Sequence: MSSIETYMQSVGEQARTASRAMMRATGAAKNQALLAMAEAILAQRAELQAANAKDVAAARANGLEAALLDRLTLSDRSIALMAEGLRQIAALPDPVGSITATSVRPNGMRVAQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALHSNVALGRIVQAGLQAAGLPTAAVQVIDTTDRAAVGKLVTMTEHVDVIVPRGGKGLISRLAQEARVPLIKHLDGNCHVYVDAAADLAKAHDIAFNAKTYRYGVCGAMETLLVHADVAQRLLPVLGQALHEHGVELRGCARALQWLPEGKPADDADWATEYLGPVLAVRVVDTIDEAMDHIARWGSGHTDAIVTENLSAAQRFQREVDSSSVYVNLPTCFADGFEYGLGAEIGISTNRLHARGPVGLEGLTTLKWVLNGEGQVRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBL65_ARATH
Sequence: MDDCSKDIINCLPDNLLCQILSNLSTKEAALTSLLSKRWRYLFALVPNLDFDVLPSLHPEVAMQDQDQTSFIDFVDRVLKLRGKDHINKFSLKCGDGIEDEDVFPWILNTLRHGVSDLSLHVSPSLVYWLPSKVFASKTLVRLKIGPKDGPRVKLRNVCLPKLKTLNLDSVVFEEGKIGFAKLLSGCPVLEELSLLNLAWDRWDSCSVSSKILKRLTLYCAHSSRNPKSVSFDTPNVVYFEYSDNIANKYPKVNFDSLVEASIGIRMTKVQKANARYVSDVDEETEMVGNATDLLMGICNVKTLYLSYDTLETLNLCCQVIPVFNNLTHLTIESHPELGWESLPNLLKSCPNLGTLVFQGLLHKATDRCGDVCMCQGLENSHSCLSSSPVKCLKILKFGETNDDDDMEIEMEQIKNFLEKMPNLEQLIIYYESSIDNDLVRVSSQLQEVPTVASLKCKIQVISDNLSLSSTLPISLSMENGFHL
What are the official names of this protein?
F-box/LRR-repeat protein At3g59210.
Protein: RL19_CAUSK
Sequence: MAANIIKELEREEAQRLLAARAIPEFEPGDTLRVNVRIKEGERERVQAYEGVCIARSGGGVHESFTVRKISFGEGVERLFPLLSPSIESIEVKRRGVVRRAKLYYLRDRRGKSARIAERSNVRKVEVADAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SYS_CUPMC
Sequence: MLDIQLLRKDIDAVAQRLATRGFQLDVALFQALEAERKQLQTQTEDLQARRNSLSKQIGMLKGKGEDASGPMAEVAGIGDTLKASAQRLAEIQDQISDAMLSIPNLPHESVPTGKDETENVEVRRVGTPRTFDFEIKDHVDVGARLGLDFETATKVTGSRFAFLRGGVARMHRALVQLMVDTHTLEHGYTEMYVPYIVNAASMRGTGQLPKFEDDLFKVPRKVGGEDGQDAIENFYLIPTAEVPLTNVVRDAIVAAEKLPLRFVAHTPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQVVPSEQSMDALEQMTGHAETILKKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYREISSCSSMGDFQARRMQARMRAGQGKPELVHTLNGSGLAVGRTLVAILENYQNADGSVTVPKALQPYMGGITRLEPEA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL78_ARATH
Sequence: MCTTISISISTIKPTEIFQEILGSSYSRKLLFHTHDQSPTPAPSPYVGDNNFDANVVMVLSVLLCALVCSLGLNSIIRCALRCSNLVPSEAGGDNYPVRLTNTGVKRKALKSFQTVSYSTELNLPGLDTECAICLSEFVAEERVKLLPTCHHGFHVRCIDKWLSSHSSCPTCRHCLIQTCEKIADCSQTSSLNSTQPPQDSIILQIAPLEPERWIRWFR
What are the official names of this protein?
RING-H2 finger protein ATL78, RING-type E3 ubiquitin transferase ATL78.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y3223_SHEB9
Sequence: MKPQWQQYINIIKQVVKPALGCTEPIAAAYAAAVARALLGVEPDSIAVQVSDNLYKNSMGVFVPGTGKIGLAIAAAAGAIAGNPDAGLEVLAVITPEQVAKAQALIDAGKVTVERTETAEFIYCCVIAKKGDREALVKICGGHTLIAEKRLNGESVFSVDSTQAKATGSICEGVDITIESIYRFAQEVPFEEIKFILEASELNGKLSDEGMANPYGLEVGRTMKSGIAAGIIGEDLLNKIVMLTAAASDARMGGANLPAMSNLGSGNQGIAATIPVVLTAQCYKVSEEQLARALIMSHLGAIYIKSHYPPLSAFCGNTVTSAAASMAMVYLAGGSFEQSCFAIQNVISDSSGMVCDGAKASCAMKVSTSSSAAVRSFLMALSSHNVSGQGIIATDVEKTIKNIGKMILNGMSSTDVTIIDIMSA
What are the official names of this protein?
UPF0597 protein Sbal195_3223.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: HEM1_MYCLE
Sequence: MSILLFGVSHRSAPVSVLEQLSLDRSDQIKIVDRVLQSPLVTEAMVLSTCNRVEVYAVVEAFHAGLSVIGQVLSEYSAMSIGDLTKYAYVRYSEAAVEHLFTVASGLDSAVVGEQQVLGQVRRAYAAAEANRTVGQVLHEVAQRALSVGKRVHSETAIDAAGVSVVSVALGIAGRTLGGLAGRIAVVIGAGAMGALSSSYLTQANVGRIHVLNRSLSRARRLAGKIGESGVPADVWTLNHLDEALADADLVVSCTGAVSPVVSLADVHHALAAMRRDETTRPLVICDLGMPRDVDPAVAKLPGVWVVDVEGVQREPSARASAADVDAARRIVAAEVATYLTRQRMAEVAPTVTALRQRAADVVEAELLRLDHRLPGLESAQREEVARTVRRVVDKLLHAPTVRIKQLASAPGGDSYTEALRELFELDQTAVDAVATAGELPVMVSGFSDTTRYGTSPAQSSSKYHAE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HSLV_SERP5
Sequence: MTTIVSVRRNGQVVIGGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADENSSLIITGNGDVIQPENDLIAIGSGGPYAQAAARAMLENTELSAREIVDKSLNIAGDICIYTNHFHTIEELPSKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_CORU7
Sequence: MSQFVDRVVLHLKAGDGGNGCNSVRREKFMPLGGPDGGNGGHGGDIVLEVDPQVHTLLDFRFSPHVRAERGNNGAGDDRHGARGKDLTLHVPPGTVVIDEDGEVLADLVSPGQKVIVAQGGFGGLGNASLASKTRKAPGFALLGEPGEQKDVTLELKSMADVGLVGFPSAGKSSLISVLSAAKPKIADYPFTTLAPNLGVVSVDHDTFTIADVPGLIPGASEGRGLGLDFLRHIERTAVLAHVVDAAALESERNPLDDIRALEHELDSYQSELSADAGLGDLRERPRVIILNKMDVPDAEDMADLQEEELKKFGWPIFRISTVARTGLNELRFALMDIVREHRKKVENTPEPQQVIRPQSVGPKRKGRFADFEVHEDKQNPGAFIVTGQKIDRWILQTDFENDEAIGFLADRLAKAGVEEALWQAGAVDGSEVTIGGITFEWDPQTVAGVDQTPAYGRGKDRRLEQTDRVTAEQRKRASQARRGLIDEYDYGDGEVAHTERWQG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_CAUVC
Sequence: MNKLLLVAAGGAVGSVARYLVGVGAMRVMGPGWPYGTFTVNVVGGFLMGCLASWLAHRGNTSSETWRVMLGVGVLGGFTTFSSFSLETALMIQKRAYGQAFTYSAASVLLAIAALFAGLLVARKVFA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CMOA_DICNV
Sequence: MNEFFRDDIFNRPQNVVDFRFDERTAAVFPDMIHRSIPAYASLLHMLGVIAGTYVQEGDHIYDLGCSLGGATLSLSRFIPKTAHITAVDSSPAMVQRFRAYVEGAALHHIEVLEADIIHLPLKSSRVIVMNFVLQFIPPPARDALIAKIYQALTEGGILLLAEKTQPEDDLLRTWHEAFKASQGYSALAIAQKREALENVMKIETETAERVRLQAAGFRRVLPYFQGMMFKAWVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: AML1_ARATH
Sequence: MPSDIMEQRGVSTPSHFHEDIHITSERQFGFMKTDMMPENQGGRDRLSSMPKSSWTSESYQLKPQSSFSGSHPSGSPNARNTTNGSQWESSLFSSSMSDLFSRKLRLQGSDMLSTMSANTVVTHREEEPSESLEEIEAQTIGNLLPDEDDLFAEVTGEVGRKSRANTGDELDEFDLFSSVGGMELDGDIFSSVSHRNGERGGNNSVGELNRGEIPSRTLLVGNISSNVEDYELKVLFEQFGDIQALHTACKNRGFIMVSYCDIRAAQNAARALQNKLLRGTKLDIRYSISKENPSQKDTSKGALLVNNLDSSISNQELNRLVKSYGEVKEIRRTMHDNSQIYIEFFDVRAAAAALGGLNGLEVAGKKLQLVPTYPEGTRYTSQCAANDTEGCLPKTSYSNTSSGHIGRHFPGMISSTSSDGGSMRVIHNSIGSPVNSFIERHRSLSIPIGFPPSANGISASKPVGLQEHGHHFDNSNMGIQSMPNLHPHSFSEYVDNFANGSPYTSSAFSEMVSDGSKANEGFMIHNVRGVEGFSGGGIGSPMHQSSRRPINLWSNSNTQQQNPSSGMMWPNSPSHINSIPTQRPPVTVFSRAPPIMVNMASSPVHHHIGSAPVLNSPFWDRRQAYVAESLESSGFHIGSHGSMGIPGSSPSHPMDIGSHKTFSVGGNRMDVNSQNAVLRSPQQLSHLFPGRSPMGSMPGSFDSPNERYRNLSHRRSESSSSNADKKLYELDVDRILRGEDRRTTLMIKNIPNKYTSKMLLSAIDEHCKGTYDFLYLPIDFKNKCNVGYAFINLIEPEKIVPFFKAFNGKKWEKFNSEKVATLTYARIQGKTALIAHFQNSSLMNEDKRCRPILFHTDGPNAGDQEPFPMGSNIRSRPGKPRSSSIDNYNSFSISSVSENREETPNGTDPFLKEN
What is the function of this protein?
Probable RNA-binding transcriptional activator that plays a role in meiosis and vegetative growth.  May be a downstream effector of TOR signaling pathway and recruited by RAPTOR1 for TOR substrate.
What are the official names of this protein?
Protein MEI2-like 1, AML1, MEI2-like protein 1.
Protein: RL29_TREPS
Sequence: MGRGGCAQLSYSELLSRRRELERKYLDLRFQLVVEHVDNKLMKRILRRQIAAVNTFLRHKELTELEKRGVRE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL3_POLNA
Sequence: MSLSNSLGLLGRKVGMMRLFTDDGDTVPVTVVDVSNNRVTQVKTEANDGYDALQVAFGSRKASRVTKPEAGHLAKAGVEAGEILKEFRVTADVAGKYAAGTVVPAADIFAVGQLVDVQGTSIGKGFAGTIKRHKMSSQRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHLGDVTKTTQNLDIVRIDEARQLLMIRGAVPGSKGGFVTVRAAIKAKPTAAKGAN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GLPE_COXB1
Sequence: MMYKQISHLEAWELVKKRDIVIADVRDQDSYEEEHIANALHLSMAKLQEYSEKADKEKPVLVYCYHGISSQSVAQHLVEQGFKEVYSLIGGFETWKAHHPTSDANKN
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_CHRSD
Sequence: MPLREVTMTLDSLRFDNAWARLPEDFFTRVSPATWKNTRLLDISPRGCRALGLDPACFDDDAPARETLRQLMGGETVLPGMAPLAQKYTGHQFGVYNPALGDGRGLLMGEAQTADGYWDLHLKGAGQTPYSRFGDGRAVLRSSVREYLAGEAMAGLGVPTTLALALATNDEKVQRERVEPGATLLRLAPSHVRFGHFEWLYQSRRHDDMRRLVDHVIERHRPALAASESPAEALFGDVVARTARLIAAWQAYGFVHAVMNTDNMSILGLTLDYGPYAFMDAYDPRLVPNHTDANGRYAFDQQPGVGLWNLSVLGQSLTPLAEPDALRDRLTEYEPALQQEYARLMRARLGLESVVEGDAQLVQDWLTLLAEAGADYHRAFRALGEWAVDDGEWLRQEVPVEGLSAWLSRYHERLQEEERDAASRRDAMQAVNPLYVLRTHLAQQVIEAAEAGDEAPLVEFRRLLADPFTARPGMERWAAAPPPQASVICLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: VM1_BOTFO
Sequence: TPEHQRYVELFIVVDHGM
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Snake venom metalloproteinase Bfon25, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DTWD1_DANRE
Sequence: MSEDPQPESSALSDLKIASHAPLDDAQRAGRMKCTRCGCSRMFFCYSCGALVGLQPGDVPRVTLPVKIDIIKHPNETDGKSTAVQAKLLAPQDVTIYTYPCIPELDQSAENIVLVFPGPDAMSVEELWEYFCADGRPRVKRVKAEAESLRCPIQRVVFIDSTWNQTSRIITDERLQALPNVELKSRKTCFWRRQKGSPDTYLATIEAIYYFLKDLHCHYFCEYTGEYDNLLFFFSFLHKLINKAKQAAGKA
What is the function of this protein?
Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20 in the D-loop of several cytoplasmic tRNAs (acp3U(20)).
What are the official names of this protein?
tRNA-uridine aminocarboxypropyltransferase 1, DTW domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. DTWD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPK4_PERFU
Sequence: DHLSHDVYSPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Pyrokinin-4, Pef-PK-4, YXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RAD50_SCHPO
Sequence: MSCIDRMSIMGIRSFDNRSRESIQFFSPLTLIVGQNGSGKTTIIECLKYATTGILPPNTKGGAFIHDPKICGEKEVLAQVKLAFRNTNQVKMICTRSLQLSVKKTTRQQKTLDGQLLILKDNERTTISNRCAELDSQVPLSLGVSKALLDYVIFCHQEESFWPLSEPANLKKRFDEIFESLRYAKALDQIKGLKRDQETQVKVDQATLTHYRSDKERAEKIELRVHESLKRISCIRSKVEELDQEITETARLQDELFKSTEEYEQQMITIRHLESQSDIINTTINDLKSQMTITDESSEDLEKLHSNFAEKVKEEQELYKSLEKKRSDLESLLKSRRELLEKLTGDLGKIQGEIESLEKLKVKKSTMINEIVHRYNINEINEEGIMTEVSKYASLVNKNYEISSGKLKERQVAVRARIEGIKAHEMFLNNRVSEINSSLEKQLTTQKELRSRFEILFPVKLQREDFTKDVEKSDLWIKSLRQEYESKNLLELLDKHQTALSSVENRLDEISEIVDSYHKYSGVRTKLQVFEENKTNKSAILANQLMTLKSSFSEVMSYELKDDDNYNEELDKLVEDVRKKLQEKEEAESSLRSVRERLEIRISLSVQSINDLTENKKIKTKTLKSYSGTFASMISEIKALESEIEENRKTLHSLQFGSTFYEKAIEICVDQHACQLCQRSLDKEEEKLFVEHCHSMIDVIPSKSAEVYSHLETLTKTFKNLSEAKPIFDEIELLDKRLSETKTELSDLQGDLQGLDIRKDEIQSELDTLYLRRANLEKLQLLVKDISNLEEEIRTIDRETEVLRIELPSSIAHHNLDEIYAEREKLLEKRGYLRKQIERTKLEETSFKKKIDDAVLANNEQKLKLTKLNFQVNELEQLEKDINKSSEDCDLQKKKLLEVSSKQGSQAPFLNELESEYEKLEADIQEMAQKSRTEILEANEYLHQLNEWNSELRIDVSTKFKCIKEKKSNIGEEVRIIASKIESTDDNLRKLQERLADLRTRERNASDNLRLRALMRQLEEAVTQKNYLLSQQSHDDRESFRERMQILKSKYGALNAERAGLLGECKQLENSITKDKEELNMEFKDADERFRRQLIKTKTTGKANEDLGKYAKALDVAIMQLHSMKMNEINRIVDELWKQTYCGTDIDTILIRSDSEGKGNRTYNYRVCMVKGDAELDMRGRCSAGQKVLACIIIRLALAECLGVNCGILALDEPTTNLDEENICSLAKNLSRIVEFRRKQANFQLIVITHDEQFIRLVNSDAYCSYYYRVKRDTNQKSMIVKEPL
What is the function of this protein?
Involved in DNA double-strand break (DSB) repair.  Involved in mating type switching and has a role in choosing the sister chromatid for recombinational repair.  Also has a role in telomere length maintenance.
What are the official names of this protein?
DNA repair protein rad50.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HEMH_NITOC
Sequence: MNFKGYSDYRHDTVARIGVLVASLGTPEAPTASAVRRFLASFLSDPRVVELPRPLWWLILHGIILRIRPSPVARLYQSIWREDGSPLLSFARRVGQSLQAELDSRGRSIEIRLGMRHGSPSIETALEELRQSGAQRLLVFPLYPQYSGSTTGSTFDAVAQVLSTWRWVPELRMIAQYHDHSGYLEALAETIRRSWKEAGRGERLLISFHGLPKRYLLAGDPYHCQCQKTARLLAERLGLKEGEWQIAFQSRFGREEWLKPYADHLLQAWAEAGIKRVDVVCPGFAVDCLETLEEMAQRNRELFLHAGGEEYRYIPALNDESAHIRALTDLVEQHIQGWSEADLGGGREATGQAAERSRQRALALGAKQ
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_BUCAI
Sequence: MLNYFFKKQLRLSDSTSFQDVFNGSVKKKNTLEISILGRFNLLGHPRLGLSIPRKNIKHAHNRNLIKRLVRETFRLLQYKLLSMDFVVIAKKNILFLNNTRIIDMLNSLWSNYYR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GPMB_ENT38
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQARQVAERARTLGITHIIASDLGRTQQTARIIADACGCDIILDPRLRELDMGVLEKRHVDSLTDEEEGWRRTLVNGTEDGRIPDGESMQELSVRVQAALADCLKLPEGSRPLLVSHGIALGCLVSTILGLPAYAERRLRLRNCSISRIDYQESPWLASGWVVEMAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: UNK_HUMAN
Sequence: MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPAGSPLTSSISSSITSSLAATPPSPVGTSSVPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPGSITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANSTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALEVQVKKLQEELERLHAGPEPQALPAFSDLEALSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQKRAVLPCQHAALCELCAEGSECPICQPGRAHTLQS
What is the function of this protein?
Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development.  Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system.  Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif.  Associated with polysomes (PubMed:25737280).
What are the official names of this protein?
RING finger protein unkempt homolog, Zinc finger CCCH domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the unkempt family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP2S1_BOVIN
Sequence: MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE
What is the function of this protein?
Component of the adaptor protein complex 2 (AP-2).  Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways.  Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation.  AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.  The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components.  Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation.  AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis.  AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface.  AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules.  AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway.  The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.  May also play a role in extracellular calcium homeostasis (By similarity).
What are the official names of this protein?
AP-2 complex subunit sigma, Adaptor protein complex AP-2 subunit sigma, Adaptor-related protein complex 2 subunit sigma, Clathrin assembly protein 2 sigma small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV.
Protein: H33_XENLA
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PURT_XANCP
Sequence: MTTLGTPLSPSATRVLLLGSGELGKEVAIELQRFGVEVIAADRYANAPAMQVAHRSHVLDMLDPQALRALIAQEQPHLIVPEIEAIHTETLVALEHEQGQKVIPTARAARLTMDREGIRRLAAETLGLPTSPYRFVDTAAEYREAIATVGLPCVVKPVMSSSGKGQSTLRSEADIDAAWDYAQTGGRAGAGRCIVEGFIDFDYEITLLTVRHAGGTSFCDPIGHWQKDGDYRESWQPQPMSAAALRRSQEIAQAITDELGGWGLFGVELFVKGDEVWFSEVSPRPHDTGLVTLVSQELSEFALHARAILGLPVGAENGGVIRQSGPSASCALLAHGNGVPVFDNVAEALRDPDTALRLFGKPRVDGHRRVGVTLARAGSIDAAREKARVAAAALTIQLRD
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.