PharMolix/UniProtQA huggingface dataset:
Protein: RL17_TOLAT
Sequence: MRHRLSGRQLNRNASHRQAMFRNMASSLVRHEIIKTTLPKAKELRRVVEPLITLAKSDSVANRRLAFARTRDRDVVGKLFTELGPRFQGRPGGYTRILKCGFRAGDNAPMAYIELVGRPVDAEAVTEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: UNG_SODGM
Sequence: MTQMLTWRDALAQEKTLPYFQETLAFVARERAAGMTVYPPAKDVFNAFRFTELNAVKVVILGQDPYHGPNQAHGLSFSVKPGVPAPPSLVNIYKELASDIPGFVIPNHGCLQSWAQQGVMLLNTVLTVEAGKAHSHASLGWETFTDKVIKVLNAQREGIVFLLWGSHAQKKGTIIDPKRHHVLKAPHPSPLSAHRGFLGCRHFSRANALLEQQGQQPIDWTPTLPAA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPO_CANLF
Sequence: MCEPAPPKPTQSAWHSFPECPALLLLLSLLLLPLGLPVLGAPPRLICDSRVLERYILEAREAENVTMGCAQGCSFSENITVPDTKVNFYTWKRMDVGQQALEVWQGLALLSEAILRGQALLANASQPSETPQLHVDKAVSSLRSLTSLLRALGAQKEAMSLPEEASPAPLRTFTVDTLCKLFRIYSNFLRGKLTLYTGEACRRGDR
What is the function of this protein?
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass.  Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
What are the official names of this protein?
Erythropoietin.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: SHO1_YEASZ
Sequence: MSISSKIRPTPRKPSRMATDHSFKMKNFYADPFAISSISLAIVSWVIAIGGSISSASTNESFPRFTWWGIVYQFLIICSLMLFYCFDLVDHYRIFITTSIAVAFVYNTNSATNLVYADGPKKAAASAGVILLSIINLIWILYYGGDNASPTNRWIDSFSIKGIRPSPLENSLHRARRRGNRNTTPYQNNVYNDAIRDSGYATQFDGYPQQQPSHTNYVSSTALAGFENTQPNTSEAVNLHLNTLQQRINSASNAKETNDNSNNQTNTNIGNTFDTDFSNGNTETTMGDTLGLYSDIGDDNFIYKAKALYPYDADDDDAYEISFEQNEILQVSDIEGRWWKARRANGETGIIPSNYVQLIDGPEEMHR
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.  Detects changes in external osmolarity and activates PBS2 through the stimulation of STE11 and targets PBS2 to the plasma membrane.  PBS2 activation leads to changes in glycerol production that helps to balance the intracellular and external osmotic pressures.  Activates also HOG1 in response to heat stress and mediates resistance to oxidative stress.  Involved in the regulation of the mating pathway.  May be a receptor that feeds into the pseudohyphal growth pathway (By similarity).
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1, Suppressor of SUA8-1 mutation, Synthetic high osmolarity-sensitive protein 1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bud. Bud neck. Cell projection. Note=Localizes at the tip of the mating projection during conjugation.
Protein: MURC_NITHX
Sequence: MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASEGANVVRLRDKGIKVTVGHRAENVSGADVLVVSTAIRRDNPELMAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGDFDPTVINGGIINAYGTNARLGAGEWMVVEADESDGTFLKLPTDVAIVTNVDPEHLDHFKTFDAVQDAFRSFVENVPFYGFAVMCIDHPVVQSMVGRIEDRRIVTYGENPQADARLVDLAPNGGGSHFKVVFRNRKTDAAHEVSDLVLPMPGRHNALNATAAIAVAHELGIPDATIRKAIAAFGGVKRRFTKTGEWNGVTIIDDYGHHPVEIAAVLKAARESTGGKVVAVVQPHRYTRLQSLFEEFCTCFNDADTVVVAEVYPAGEAPIAGIDRDHFVLGLRAHGHREVVPLQEPAALAGVIAGLAKPGDYVVCLGAGNITQWAYALPGELKALG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNU1_HUMAN
Sequence: MFQTKLRNETWEDLPKMSCTTEIQAAFILSSFVTFFSGLIILLIFRLIWRSVKKWQIIKGTGIILELFTSGTIARSHVRSLHFQGQFRDHIEMLLSAQTFVGQVLVILVFVLSIGSLIIYFINSADPVGSCSSYEDKTIPIDLVFNAFFSFYFGLRFMAADDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPQILQILRAIKTSNSVKFSKLLSIILSTWFTAAGFIHLVENSGDPWLKGRNSQNISYFESIYLVMATTSTVGFGDVVAKTSLGRTFIMFFTLGSLILFANYIPEMVELFANKRKYTSSYEALKGKKFIVVCGNITVDSVTAFLRNFLRDKSGEINTEIVFLGETPPSLELETIFKCYLAYTTFISGSAMKWEDLRRVAVESAEACLIIANPLCSDSHAEDISNIMRVLSIKNYDSTTRIIIQILQSHNKVYLPKIPSWNWDTGDNIICFAELKLGFIAQGCLVPGLCTFLTSLFVEQNKKVMPKQTWKKHFLNSMKNKILTQRLSDDFAGMSFPEVARLCFLKMHLLLIAIEYKSLFTDGFCGLILNPPPQVRIRKNTLGFFIAETPKDVRRALFYCSVCHDDVFIPELITNCGCKSRSRQHITVPSVKRMKKCLKGISSRISGQDSPPRVSASTSSISNFTTRTLQHDVEQDSDQLDSSGMFHWCKPTSLDKVTLKRTGKSKYKFRNHIVACVFGDAHSAPMGLRNFVMPLRASNYTRKELKDIVFIGSLDYLQREWRFLWNFPQIYILPGCALYSGDLHAANIEQCSMCAVLSPPPQPSSNQTLVDTEAIMATLTIGSLQIDSSSDPSPSVSEETPGYTNGHNEKSNCRKVPILTELKNPSNIHFIEQLGGLEGSLQETNLHLSTAFSTGTVFSGSFLDSLLATAFYNYHVLELLQMLVTGGVSSQLEQHLDKDKVYGVADSCTSLLSGRNRCKLGLLSLHETILSDVNPRNTFGQLFCGSLDLFGILCVGLYRIIDEEELNPENKRFVITRPANEFKLLPSDLVFCAIPFSTACYKRNEEFSLQKSYEIVNKASQTTETHSDTNCPPTIDSVTETLYSPVYSYQPRTNSLSFPKQIAWNQSRTNSIISSQIPLGDNAKENERKTSDEVYDEDPFAYSEPL
What is the function of this protein?
Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+).  May represent the primary spermatozoan K(+) current.  In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+).  Critical for fertility.  May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
What are the official names of this protein?
Potassium channel subfamily U member 1, Calcium-activated potassium channel subunit alpha-3, Calcium-activated potassium channel, subfamily M subunit alpha-3, KCa5, Slowpoke homolog 3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa5.1/KCNU1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIE_GEODF
Sequence: MFKLTEKGEKIQEMFDTIAPRYDFLNRVLSFGIDRSWRRFAVKKIKYAPNGRILDVATGTGDVALEIAARTPSSVSITGIDFSGEMVELGKQKVAASSYAGRINMQVAPCEDIPFADDSFDSITIAFGIRNVVDRSQGLKEMYRVLKPGGRVVILEFSTPRFVLFKHLYHFYFLKVLPVIGGLFSKFSAYKYLPDSVIEFPSQDQFKATMAGVGFKNTQHHDLTLGIATVYTGEK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: NOP9_FUSV7
Sequence: MPKPRTKRGHGREEKKRKRREEAESYEAHENDSKRQRTTDENGYQDGQEAQENGIGEKEFFGMLADEEQEYFRRADELLELNQFPSDEERDVFLENVWKEAENKELKLASSQSCSRLMERLIQLSTTAQKKRLFEAFAGHFLSLVQHRFASHCCEALFLRSAGVVTKELSGFVGFVLDTKGAGGDAEKPEAAMEHLFLATLDELEGSLSYLITDRFASHTLRVLLLVLSGRPLEDSSSRTLMKSKKKEKISVSGAEAADEANKGLRAVPPSFTMAATKIIQDSTAGMDATSLRVLARHPMGNPTLQLLLELDLTLNKGEQKADAERPTLLFQLLPGAPKSLSDGSSEASEFINGMIYDQIGSRLIETLITHAPGKVFKALNQNIFLPRIEGYVRNDVSSYAAIRVLNRLSKDDLVQAVEQITPTVPQLVTKSRFNVLKTLFERCAARGANDEIKKLNKGLKEGCGKTPADLVTYLCGFKDEEKKKKDVQQLSKNEYAIQSHGAQLLTALLSIPGPVKGVQESLLAVEPTVLVRLATTSMPTVTVLTTALATPSSNPAFHKSIVSSLLPHIHELAVQQFGHNLINAIAEVPSKGKERSVPFHMKEAIMARLGEHEAELRDSWMGRSVWRNWKGDMWKTRRRDWKVWMREVDAHIESTLPQRGRAAEKQQAAQDKPSKKEEPVVEDKMEVDEVVEKPEEEKKKEKKDKKDKKEKREKKEKKDKKEKKEKKKSKPEEAEVVAEDEE
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: P32_TRVPP
Sequence: MVIVTKGAYVHEFPRTAEWNAFAQILSREHGYIVSDTALEGAAKPYYVVNSSGFYGPPGLDGLISTLDRELQYYSKLLYEIKGLGVMSDENVFGTQYDGNLTARVSRLERRLNPMSNIGSSSRPWSEHKSAVKKADLERYVYANFADWSNHLGPAGKSTREVVKYLMYRMGYYSDTSGIGHDLNYKHFRDHLDIYNLTCSPPFLVSSAVVDGHYARDKFVSFQGVCGFNPMFPDVNGLKSSWSLGRQLDDIRSQKKEVSGTNQEPNYYYDGDTLKPIGSGASVVGERRPGWR
What is the function of this protein?
May be involved in transmission by vector nematode species.
What are the official names of this protein?
32 kDa protein.
Protein: SYE_PSEF5
Sequence: MTTVRTRIAPSPTGDPHVGTAYIALFNYCFAKQHGGEFILRIEDTDQLRSTRESEQQIFDALRWLGINWSEGPDVGGPHGPYRQSERGDIYQKYAQQLVDLGHAFPCFCTAEELDQMRAEQMARGETPRYDGRALLLSKEEVARRLAAGEPHVIRMKVPTEGVCVVPDMLRGDVEIPWDRMDMQVLMKTDGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLILLYEYFGWEQPQLCYMPLLRNPDKSKLSKRKNPTSVTFYERMGFMPEAMLNYLGRMGWSMPDEREKFSLQEMVDNFDLSRVSLGGPIFDIEKLSWLNGQWLRDLPVQEFASRVQTWALNPDYMMKIAPHVQGRVETFSQIAPLAGFFFAGGVNPDAKLFESKKLSGDQVRQLMQLILWKLESLRQWEKDSITATIQAVVESLELKLRDAMPLMFAAITGQASSVSVLDAMEILGPDLTRFRLRQAIDLLGGVSKKENKEWEKLLGAIA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_RIPO1
Sequence: MQEFDKSISFDGRDIRLKLGLLAPQAGGSVLIQSGDTAVLVTATRATGREGIDFLPLTVDYEERLYAAGRIPGGFLRREGRPPEKAILISRLIDRPLRPLFPQWLRDDIQIIATTLSMDEEVPPDVLAVTGASIAVIAARIPFFGPMAAVRVGLIGDDFIINPTYREIEIGDLDLVVAGSPDGVVMVEAGANQLPEQDIIEAIDFGYEAVRDLIQAQRDVMEALDIPLVIGEPPAVNEVLQSFISDRASESIKKVLMQYNLDKNARDEQLDEIKETAITNAIAELPEEDPVKVAATEEPKAVSNLYKDLTKKLMRSQIITDGVRVDGRKLDEVRPISSRVCLLPRRVHGSALFARGLTQVLSLATLGTPGDAQDLADDLHPEDEKRYLHHYNFPPFSVGETKPLRSPGRREIGHGALAERAITPILPPQEEFPYVIRVVSEVLSSNGSTSMGSVCGSTLALMDAGVPITKPVSGAAMGLIKEGDEVRILTDIQGIEDFLGDMDFKVAGTDSGITALQMDMKITGLSMEIVAKAIEQALPARLHILDKMMETLSTPRKNLSPYAPRLLTMKIDPEQIGLVIGPGGKTIKGITEQTGSKIDIADDGTVTIAALEAEKAEKAKQIIYNMTRKLNEGEVYMGRVTRIIQIGAFVEVLPGKEGMIHISQLAEGRVGKVEDEVAVGDEVIVKVREIDAKGRLNLTRLGIHPDEAAAARKAVAPV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D1A_ILLWI
Sequence: CAKKRNWCGKNEDCCCPMKCIYAWYNQQGSCQSTITGLFKKC
What is the function of this protein?
Inhibits tetrodotoxin-sensitive sodium channels by binding to site 3.  It slows the inactivation, causes a prolongation of action potential duration resulting in repetitive firing in autonomic and motor nerve fibers.  Does not depolarize the resting potential.  Does not affect tetrodotoxin-resistant sodium channels.  This lethal neurotoxin is active on both insect and mammalian voltage-gated sodium channels (Nav).
What are the official names of this protein?
Delta-hexatoxin-Iw1a, Delta-HXTX-Iw1a, Delta-atracotoxin-Hs20.1a, Delta-ACTX-Hs20.1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 06 (delta-actx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTL_WOLWR
Sequence: MAIILLDTKTINRIAAGEVIERPASVVKELVENAIDAGSLEIEIKIESGGRNLIIVTDDGNGVEKNDLELAFMRHATSKLSDSELIEIKHLGFRGEALPSIAAVSRIKLSSKAREASEAWSISYEGGEKIGEQTPYSLSQGTHIEVRDLFFATPNRLKFLKTERAETQSIVDIVNNLAMINYHIGFTLTSGNKKLLKYAKQTSLFHRLCEVEEEFQGSSLEINEEEDGIKLTGHICKPTVNRGKSTQIYTFVNGRPIKDNLLIGAVRYAYHDFIPSDRYPFAALHLEIPYDQVDVNVHPNKSEVRFQNKKLIYEIMTRGLIKALSRRIGTFPAHDQKMDSTLPDPFDKPDVQNERRPSPFENQLIKEFASPNEKAKGLSEQSKSFDYTGIQKFPAQAEAMVLEKKVLEQVDLIESHPLGFARCQVYNTYIIAEVRDKLIIVDQHAAHERLVYECLKQKSSIKRQKLLLPETVEIKNQAGMEMIEIYKDKLFEMGFDIEIKSENKVIVKEIPAILGAIDVKEMLINIIDRLTEIEDTLPVEDKVNKILATIACHGSIRAGRKMRLDEMNELLRQMEKTPYSGQCNHGRPTYIEMKLSDIEKLFERR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MORF1_ARATH
Sequence: MAMISHRLRRALLTATSYVNRSISSSITPASDFPSVSAAVLKRSVIGRSTEVATRAPARLFSTRQYKLYKEGDEITEDTVLFEGCDYNHWLITMDFSKEETPKSPEEMVAAYEETCAQGLGISVEEAKQRMYACSTTTYQGFQAIMTEQESEKFKDLPGVVFILPDSYIDPQNKEYGGDKYENGVITHRPPPIQSGRARPRPRFDRSGGGSGGPQNFQRNTQYGQQPPMQGGGGSYGPQQGYATPGQGQGTQAPPPFQGGYNQGPRSPPPPYQAGYNQGQGSPVPPYQAGYNQVQGSPVPPYQGTQSSYGQGGSGNYSQGPQGGYNQGGPRNYNPQGAGNFGPASGAGNLGPAPGAGNPGYGQGYSGPGQEQNQTFPQADQRNRDWNNNNPAGQPGSDQVRSRSIMNLASFFFDILIRH
What is the function of this protein?
Involved in organellar RNA editing.  Required for the processing of numerous RNA editing sites in mitochondria (PubMed:22411807, PubMed:23818871).  Binds to the mitochondrial MEF19 and MEF21 factors, two pentatricopeptide repeat-containing proteins involved in RNA editing (PubMed:22411807).
What are the official names of this protein?
Multiple organellar RNA editing factor 1, mitochondrial, RNA editing-interacting protein 8.
What is the protein family that this protein belongs to?
Belongs to the MORF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YCIU_SALAR
Sequence: MEMDLNNRLTEDETLEQAYDIFLELAADNLDPADIILFNLQFEERGGAELFDPSEEWQEHVDFDLNPDFFAEVVIGLADTEDGEINNIFARVLLCREKNHKLCHILWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: SRY_MEGNO
Sequence: MFRIVNGEDYSPAVQQRNSLDFGKAPSLLWTDHGGSNDRCETGGNGRESGQDRVKRPMNAFIVWSRDQRRKVALENPQMQNSEISKRLGYDWKMLTEAEKQPFFEEAQRLRAMHRDKYPGYKYRPRRKAKRSQKLLPADSSVLCSRMHIEETLYPFTYKDGCAKATRSRMESRLSRSQPTNTASSLLPQEHRSSWTSLSHNRVT
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: RL30_SALTY
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAVRGMVNAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PSBA_ILLOL
Sequence: MTVILERRESTSLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSING
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: IPYR_NANEQ
Sequence: MEVYAFIEVPKGSNVKYEYEDGKLKVDRILYGAMFYPYNYGFIPETLEEDGDPLDVLVITEEPLVPGSYIKVKPIGVLVTEDEKGVDRKIIAVPVKKVDPIYGEIEDISELKEGIKLKIKHFFERYKELEPGKFVKVKEFLGKEEAEKIIKQAQENYKKQ
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AEP1_YEAST
Sequence: MITTVQEISKWRNLCFIRMQSRKWYPVLKKTPLVADGRKIIKHADKVPHPEEIIHPFYQPTAIEQFTACATEYNPSLLDGKKIAPSLIKHPVSLKTILVDSKLKFDDIRGVNKWLMEFVARRQHQRNIVLTPASKSVRSFHVLHLSSTDIAKLRGLENILSEIENTNDLQSRVESVNNELQNIFDRDSKQTRLFCENILAYLIKNYGNSTEKLILLINVTEMQLYSRLDQMKAMNIILYNILCKVEANENPPYSPTLVTALENLLAAINNRFFPGRCENSLHPIVIEQLLSYFIKTGNLNESKNFLGHLIKKGILPEATIINRYLEAIDVHFDKSTKIFDIRSKFAFIADLAPIIENYGTIDLFKFLIPMCRHFDELCSLLNIIRKSNNAKRAVDSTLPIFIKKVLTFTKDPMINSGNLSTVFNIVSPIYGQNVPSEFVEKFILSFALQGNYTMMAHMIDTYKIKLSHKYQLQIIRALKNSERNHALKNTGAVGYNKEFKKYFIEKYLNCTEREALRP
What is the function of this protein?
Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.
What are the official names of this protein?
ATPase expression protein 1, mitochondrial, Nuclear control of ATPase messenger RNA expression protein 1.
What is the protein family that this protein belongs to?
Belongs to the AEP1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MED15_DANRE
Sequence: MDVPGPDSDWRSPAFRQKVVAQIEEAMRKAGTGHTKSSTEMESHVFTKAKTREEYLSMVARLIIHFRDIHKKAQGGPDPINALQNLPGGVPGVIGPRPPGAQMGGMGQMSMGPHAMQGVAGGQQGAGAAGPMQQMIQQQQQQQQQQQQQQSIQFQTFQPQQQQQATMQSQQPSAMFQQIRLQQLQQHHQNQQMQHQNQQQQQAQNQQQQNQLHQTRMQQQLQLQQLQQQQQQQLHQQQVHAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQSIQQMQQQQQLQVQAQGQPQVQGQGGAVQMPPHSQQQQVLVPQMVQGQHSQMSALSQQQQLKLQQAMQARMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQVQQVQQASQLTAVPGQMMPRPGMQIPPRLPRATPNSAIPQNPVAIGGQQMPQAQQMMSSPSPVQVQTPQSMPPPPQPQPSPQPPSSQPNSVSSGPTPSPGGFQPSPSPQPSQSPASSRTPQSYPLQVPSPGPLNTPGNPSSVMSPAGASQSEDQLYMDKLRQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLNILTDPNTRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPCTKKQYLCQPILDAVLANIRSPVFNHSLYRTFAPAMTAIHGPQITGPSIPSRKRKLEDDERQAIPNILQGEVARLNSKFLVNLDPSFCSNNGMVHLICKLDDKNLPSVPPLQLSIPADYPDQSPHWEDDGQQYEANPFLRTVHKNMTSKLLQLPDKHSVTALLNTWAQSVRQACLSA
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Required for cholesterol-dependent gene regulation (By similarity).  Positively regulates the Nodal signaling pathway.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 15, Mediator complex subunit 15.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 15 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PDC10_XENTR
Sequence: MRMTMEEMKNEAETTSMVSMPLYAVMYPVFNELEHVNLSAAQTLRAAFIKAEKENPGLTQDIITKILEKKSVEVNFTESLLRMAADDVEEYMVERPEPEFQELNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKALNVFISANRLIHQTNLILQTFKTVA
What is the function of this protein?
Promotes cell proliferation.  Modulates apoptotic pathways.  Increases mitogen-activated protein kinase activity.  Important for cell migration, and for normal structure and assembly of the Golgi complex.  Important for KDR/VEGFR2 signaling.  Required for normal cardiovascular development.  Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development.
What are the official names of this protein?
Programmed cell death protein 10.
What is the protein family that this protein belongs to?
Belongs to the PDCD10 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PSBL_SYNPW
Sequence: MERNPNPNNLPVELNRTSLYLGLLVVFTTGILFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS15_FRASN
Sequence: MPLSGDVKQKIMSDYATVDRDTGSPEVQVAMLTRRISDLTEHLKVHKHDHHSRRGLLLLVGRRRRLLNYLAKTDINRYRALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: OCA1_YEAST
Sequence: MTSKVGEYEDVPEDESRLTEENVSVPEEEVEDEDEEEDDDDDHIYINEETESGREKVLVSHAPQERIVPPLNFCPVERYLYRSGQPSPVNFPFLLNLKLKTIIWLSNEEPQDTLLEFCDTHRINLQFAAINPDAGEDDNPWDGLTEHSIINVLQTIVTQENYPLLVCCGMGRHRTGTVIGCLRRIMGWNLASVSEEYRRFTGSRGGRILVELLIEAFDTNLVKIDKNKAPSWLLTALE
What is the function of this protein?
Putative tyrosine-protein phosphatase required for protection against superoxide stress.  Involved in cell-cycle delay in response to linoleic acid hydroperoxide (LoaOOH).
What are the official names of this protein?
Putative tyrosine-protein phosphatase OCA1, Oxidant-induced cell-cycle arrest protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.