PharMolix/UniProtQA huggingface dataset:
Protein: VPS35_SCHPO
Sequence: MNGINTANEEITRSLEESLNICKQSSRLMQRNLQTGRLMDAFRNCSISLVEMRNSALTPKQYYELYMFNMESLRLLGGTLLETHLNGTHNLMDLYELVQYAGSIVPRLYLMITVGSAYLETPNALVREIMNDLLDMCRGVQHPLRGLFLRHYLLTQTRKGLPLGSEDEEDASRKGTVLDSVKFLVINFTEMNKLWVRIQHLGPIKEFSKRTQERNELKVLVGLNLVRLSQLNLDIDTYRDHVLPAIIEQIIECRDSLAQEYLVEVICQAFSDNMHLQTLDTYFGTVIKLSPSVNVTQLVVAMLNRLTDYVQREYESDSSNEDESETVTEKLGDIKINEEVQQKDEQECPGDKVIPPEYAIQEVLWSHVVEVIQSRSGLPLDCIVSILSSILNFFLRCYPYKPQYADRVFQYINEHIINQPSLRSALHERPLQKSLCAILLLPLTYFPSFSYCLELQNFLPVFNAQDPNLRYDIARMIVQKIIEKGHSLSELTEAQELLGFVSVIIEKKGVDSLDDLQNVALMVHYLNNDDPQIQIEILRSLKDTFIKAGENVKYLLPVVVNRCIFLARNFRIFKCMDWAEKVRLLWEFVNTCINVLYKNGDSLELCLALYLSAAEMADQENYPDFAYEFFTQAFSIYEESVLDSELQYQQLLMIIGKLQKTRNFSVDDYDTLITKCTLYASKLLKKPDQCCGIYLASHLWWQVASGEDSRPFQDPKRVLECLQKSLKIADACMDQLTSLKLFINILERYFYYYDQHCESIIAKHISGLIDLTEQNMRSILISSPADLIASDPRAYASSIWEVANVSVIDSLKNHLERATAYAEKRSEDERWSSIFQ
What is the function of this protein?
Plays a role in vesicular protein sorting.  Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor vps10.  Required to form proper forespore membranes.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 35.
What is the protein family that this protein belongs to?
Belongs to the VPS35 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: YLKC_SCHPO
Sequence: MTIWNVAALTGLLSVGLGAYGSHGLQKRVQDPHLLKSWSTACTYLMFHSLATMAVSLHPVYGKSRWTGPLLITGSCLFSGTIYGLCLLPKGHSLRRILGPLTPIGGLVMLTGWATMLV
What are the official names of this protein?
UPF0382 membrane protein C1782.12c.
What is the protein family that this protein belongs to?
Belongs to the UPF0382 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PURQ_THEVO
Sequence: MKQSPKIGILLMEGTNNETEVYYSVKRSGGSPDFIHINDLSAGRKRVSDYDGLIIPGGFSAGDYIRAGVIFAARLGAVAGKEIREFVDDGKPLIGICNGFQVLMEMGLIYDRSKITLTNNESNRFECRYTYMKMTSRNRIFQSGFYGKGVFQVPVAHAEGRIAVSERSVLKKLYENDQVVFKYSNENDVTDEYPWNPNGSIDSVASLSNEAGNVIGLMPHPERIYYRYQAMYLETEKDEVAGKIFYDSLVNYARDRNG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_SULTO
Sequence: MEFKLIAEYFDKLEKISSRLQLTALLTDLFKKADKNVIDKVVYLIQGKLWPDFLGYPELGVGEKLLIKAISIAVNVKEEVVEEQLKVVGDLGEVAMRLKKTPQSASILSFLGAQSNEGLTVEETYESLTKIALASGEGSRDIKIRSLAGLLKKASPLEAKYIVRFVDGRLRVGIGDATIMDALSTAFTGSTSFRPLIERAYNLRADLGNIAKIIAQQGVEALKDIKPQVGIPIRPMLAERMSDPAEILAKVGGEALVDYKYDGERAQIHKKDKEVYIFSRRLENITRMYPDVVEYVREYINANEVIIEGEIVAVDPESNEIRPFQELMHRKRKNDINEAIKEYPVNVYLFDLMLYEDADYTMKPLPERRKKLEEVIKPNDKLHIAHHIYTNNVDKLMEFFYDAISNGAEGVMVKSVAKDSIYQAGSRGFLWIKLKRDYQSEMADSVDLVVVGAFYGRGKRGGKLSSLLMAAYDPETDTFKTVCKVASGFSDAELDELQKKLMEIKLDKKDPRVDSQLEPDIWVEPKYVAEIIGAEITLSPEHTCCKDMVSKGAGLSVRFPRFIRWRDDKSIEDATTPKEIYEMYKMKLRKKEEEQHTDEA
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: EIF3D_CAEEL
Sequence: MALPKFELLSLADNTVGWGPLASSSSADEPVPFQQFNKADRIGRVADWIGVDRFYRRGNERYNERVYGSAANAGSQFDYIHGMDEHNFQLVDTSKPMARNPQRNFRVRQMHLRKMMQKENEKREMVNQSTNLRMKRSIAKEQQRAFKMWQRRGGNARQGQRGQGGRFGGDRPKERLPSVQVRPEWVVLEEMNLSAFSKLALPNIPGGDDIGDHQYGSLQYYDKTIDRVSVKNSIPLQRCAGVFYNVTTTEDPVIQELAQGGAGNVFGTDIILATLMTAPRSVYSWDIVAYRVGDKLFFDKRNTRDILNPVETLTVSETSAEPPSFDGNGINNAKDLATEAFYINQNFRRQVVKRNDAGFTFKNARAPFEDEETGESGTAYKYRKWNLGNGVDGKPVELVCRTELDGVIHGLGNETQTLTIKAFNEWDSTQSGGVDWRTKLDVQKGAVMATEIKNNSAKVAKWTLQALLAGSDTMKLGYVSRNNARSTQNHSILLTQYVKPTEFASNIALNMDNCWGILRCVIDSCMKQKPGKYLLMKDPQSPVIRLYSLPEGTFESERESSDEENSDDDQ
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d, Eukaryotic translation initiation factor 3 subunit 7.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPG1_HYPJE
Sequence: MKGLILVGGFGTRLRPLTLTLPKPLVEFCNKPMIVHQIEALVAAGVTDIVLAVNYRPEIMEKFLAEYEEKYNINIEFSVESEPLDTAGPLKLAERILGKDDSPFFVLNSDVICDYPFKELLEFHKAHGDEGTIVVTKVEEPSKYGVVVHKPNHPSRIDRFVEKPVEFVGNRINAGMYIFNPSVLKRIELRPTSIEKETFPAMVADNQLHSFDLEGFWMDVGQPKDFLSGTCLYLSSLTKKGSKELTPPTEPYVHGGNVMIHPSAKIGKNCRIGPNVTIGPDVVVGDGVRLQRCVLLKGSKVKDHAWVKSTIVGWNSTVGRWARLENVTVLGDDVTIGDEIYVNGGSVLPHKSIKANVDVPAIIM
What is the function of this protein?
Involved in cell wall synthesis where it is required for glycosylation.  Involved in cell cycle progression through cell-size checkpoint (By similarity).
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase, GDP-mannose pyrophosphorylase, GTP-mannose-1-phosphate guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YD23A_YEAST
Sequence: MESQQLHQNPHSLHGSAAASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAKTKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTSRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty2-DR3 Gag polyprotein, TY2A, TYA, Transposon Ty2 protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_STRP3
Sequence: MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEGLQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKNFNGIKGGGAALLMEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLEAPTAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RPPH_SPHAL
Sequence: MIDHDKLPYRPCAGVMLANRDGRVFVGQRLDTSSEAWQMPQGGIDEGEDAEKAAIRELGEETGIHGGLVDIIARSREEYFYDLPDHLIGKMWGGKYRGQRQHWFLMRFMGEDSDIDIHTRHQEFRAWRWVDLGEIEKLIVPFKRALYRGLIEEFGPLV
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PNP_METSB
Sequence: MFEIHREELDWAGRKLTLETGRIARQADGAVLATYGETTVLATVVSARTPKPGIDFFPLTVNYQEKAFAAGRIPGGYFKREGRPSEKETLVSRLIDRPIRPLFPEGYRNDTQVVVTVLSHDLENDPDILALVATSAALTISGIPFMGPVGGARVGYINGALKLNPTVDELKESALDLVVAGTGDAVLMVESEAKELSETLMLEAVMTGHRGFQPVIDAIIRLAEKAAKEPRELAVADKAEVEAAVRDIAEGELREAYKITAKQERYKAVDAVKAKVALALFPEDAEPRFSKEKVAEAFHDLQAKVVRWNILDLGVRIDGRDLKTVRPILAEVGILPRAHGSALFTRGETQALVVATLGTGEDEQFVDSLEGTYKERFLLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAVRPMLPTAAEFPYTIRIVSEITESNGSSSMATVCGSSLALMDAGVPLKRPTAGIAMGLILEGERFAVLSDILGDEDHLGDMDFKVAGTEEGVTSLQMDIKVAGITEEIMKVALDQAKGGRLHILGEMSKALTGARAELGEFAPRIETLKIPTDKIREVIGTGGKVIREIVEKTGAKINIEDDGTVKVASSDGNSIKAAIAWIKSIANDPEVGQIYEGTVVKVVDFGAFVNFFGSKDGLVHISQLAKGRVAKSSDVVKEGEKVKVKLLGFDDRGKVRLSMRYVDQETGEDLEAKEKAEQQASVD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_RHILO
Sequence: MQVLSVTPEIFPLIKTGGLADVTGALPVALAAKGVTMRTLIPGFPAVMEGFKKRKAVYQYPLLQGGKASIHAVQIAGLDLFVLDAPHLFDRPGGPYGNASGADWPDNWRRFAALSQAGADIAGGAISGYLPEIVHAHDWQSAMTLAYMRYGKAVGTPSMMTVHNLAFQGQFGAGIFGELGLPAVAMALDGVEYYGGVGFLKAGLQAAWAITTVSPTYAQEIRSPEFGMGLDGLINMRSSDLYGIVNGIDTAIWDPETDKHLVSNYTATTLKARAPNRAAVEERFGLDRDDSPIVCVISRLTWQKGMDILATVIDGIVATGARLAILGSGDAGLEGALLAAAARHRGRIGVVIGYDEGLSHTMQGGCDAIIIPSRFEPCGLTQLYGLRYGCVPVVARTGGLADTIIDANEAAMAAGVATGLQFAPNNGGAMLHAIRRLVDAYADPAAFETIQRQGMKADVSWDKSAEKYLELYRLLLSKRVA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: ISPG_XANC5
Sequence: MHDAVTRPTPPADATAWPRRITQAVKIGSVTVGGGHPVVVQSMTNTDTADIAGSVKQVADLWRAGSEMVRLTVNNAESAAAIPRIVDKLRMMGIEVPLIGDFHYNGHQLLAAEPACAEALAKYRINPGNVGFGKKKDLQFGQLIEFAIKYGKPVRIGANWGSLDQSLAAQLMDENSQRDTPWDAGRVLREALIRSAVDSAERAVELGLPRERIILSAKVSGVQELIAVYRDMASRCDFALHLGLTEAGIGSKGIVASAAALSVLLQEGIGDTIRISLTPEPGQSRTQEVVVAQELLQTTGQRAFTPMVTACPGCGRTTSEFFQELAGVVQNHVRAKMPEWKITNPGAENMTLAVMGCVVNGPGESRHANIGISLPGTGEAPSAPVFIDGEKSVTLRGENIAYEFIELIDQYVERTYVRRAG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RIMO_SACD2
Sequence: MTVNTFDPSKASPVTHASDSASKTPEPNAVAAPSSELGNRVGFVSLGCPKALVDSERILTQLKLDGYDVVPSYNDADVVVVNTCGFIDSAKQESLDAIGEAMKENGKVIVTGCMGKGNDAQVIKETYPNVLSVTGPAAYEEVMGAVHGYIPPKKEHNPLIDLVPPQGVKLTPRHYAYLKISEGCNHRCTFCIIPDMRGDLVSRPIGDVLGEAERLVAAGTKEILVISQDTSAYGVDVKYRTGFWQGRPVKTRMLEMCEALGELGAWVRLHYVYPYPHVDNVIPLMAEGKILPYLDIPFQHASPQVLKNMRRPAHQEKTLERLAKWREMCPELVLRSTFVVGFPGETEQDFQILLDWLQEAQLDRVGCFEYSPVEGAKANALPNHVPDEVKRERWERFMETQQAISAAKLKQKVGYEMDVIIDSIDGDIATGRTYADAPEIDGVVTFSGAAGMKVGEFSAVEITGSDDYDLTGIAVEDEQ
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1322_METST
Sequence: MPKNTLHIKNIDIQTTHIMLKTDINCDIKPFIQNQREIILNEIKENPNFLKSYTPIPLIDKKPILKLMTKAGEIANTGPMAAVAGSISEMCLDYLESFKSKFSIVENGGDIALKTNKKINMGIYAGKTSFSYNYGFKIKPKPYKYGICTSSYDGPSKSFGSTDATIVFSKQSSIADSLATSIGNYGNGNTENEVVHNALSYAEKYSDYYEGVLVIKGETLGKTGHIPQLISINNTHVKEAFEIE
What are the official names of this protein?
UPF0280 protein Msp_1322.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: ISPE_ACTP7
Sequence: MTKKIILPSPAKLNLFLYITNKRVDGYHELQTLFQFLDFGDDISLEVNESGEIELLNAIEGVAKEQNLIYRAAKLLQNHTACSKGAKIGVTKRLPMGGGVGGGSSNAATVLVGLNHFWQTGLSLEQLAELGLSLGADVPIFVRGFAAFAEGVGEKLVACQPRESWYVVLKPNVSISTAAVFQDPNLPRNTPKRTLSRLLSEEWTNDCEKVVRDHYFEVEDLIAELLQYATFRLTGTGACIFAEFESEAEAKAVFAHKPHNIFGFIAKGQNRSPLHQMLNLTTFPQ
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: EDD_HELPY
Sequence: MPKHSLEQIKEKITERSKKTRELYLENIFNPKNQPKIESLGCANIAHVTASMPEHLKMPLGSHKRKHFAIITAYNDMLSAHQPFKNYPDLIKKELQEHNAYASVASGVPAMCDGITQGYDGMELSLFSRDVIALSTAVGLSHNVFDGAFFLGVCDKIVPGLLIGALSFGNLASVFVPSGPMVSGIENYKKAKARQDFAMGKINREELLKVEMQSYHDVGTCTFYGTANSNQMMMEFMGLHVANSSFINPNNPLRKVLVEESAKRLASGKVLPLAKLIDEKSILNALIGLMATGGSTNHTLHLIAIARSCGVILNWDDFDAVSNLIPLLAKVYPNGSADVNAFEACGGLVFVIKELLKEGLLFEDTHTIMDTETQKGMQNYTKTPFLENNQLVYKDAINHSLNTDILRPVSDPFAANGGLKILKGNLGRAVIKISAIKDEHRKVKARAIVFKTQSEFLERFKNKELERDFVAVLPFQGPKSNGMPELHKLTTNLGALQDMGYKVALVTDGRMSGASGKVPSAIHLSPEGALNGAIIKIKDGDLIELDAPNNALNVLEKDFEKRGINPLFLETLENLEKPSFGLGRELFTSLRLNVNTAEEGGMSFGIKV
What is the function of this protein?
Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.
What are the official names of this protein?
Phosphogluconate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: WSD9_ARATH
Sequence: MEKKMKEEEEEPLSPMARAFQEPSIDCGIVIKFGCKTKINPDVIVDSLKLNVFKHPRFCSLLDDDGTKWLRTDVVNVEEHVFVPDIDPKLTEEDVEWFVEDYISSITMIPLDRTKPLWEVHILNAKTSDAEAICVIRCHHALGDGVSILSLILASTRKTSEPEAFSTLPVPKCRESYNHRRGFSFFRLVLVVCSTVRLIWNTLVDSFLCMATIFFLKDTDTPLKGKPGAIKKFSHRIVSLDDIKLIKNAMEMTINDVLLGVTEAALTRYLHQSYDKTNEEAGTSLTPNRQDLLDRIRLRSLIVVNLRPTGSQSIADMMAKGSKCRWGNYISVILFPFTIALQSDPLVYLSNVKSMIDRKKNSLITYIIYTFSEFVIKAFGINVAVAFQRKIMLNTTMCISNLPGPTEEVSFHGHPIAYFAPSIYGLPQALTIHYLSYANKMIISVAVDPMIIDAHKLCDELEESLKNMKLAILEKGLPNHVN
What is the function of this protein?
Bifunctional wax ester synthase/diacylglycerol acyltransferase (By similarity).  Involved in cuticular wax biosynthesis (By similarity).
What are the official names of this protein?
Wax ester synthase/diacylglycerol acyltransferase 9, WS/DGAT 2, Diacylglycerol O-acyltransferase WSD9, Long-chain-alcohol O-fatty-acyltransferase WSD9.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the long-chain O-acyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GLNE_ECOSE
Sequence: MKPLSSPLQQYWQTVVERLPEPLAEKSLSAQAKSVLTFSDFVQDSVIAHPEWLTELESQSPQADEWQHYAAWLQEALSNVSDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILQQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLSVIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNDREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQLTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVPEDCFTAERELVRASWQKWLVEE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: SHPS1_BOVIN
Sequence: MEPARPAPGRLRPLLCLLLAASNAWTGTAGDGELQVIQPERSVSVAAGETATLHCTVTSLSPVGPIKWFKGTGPGREFIYSQKEAPFPRVTNVSDATKRNNMDFSIRISNITPADAGVYYCVKFRKEERGDMEFKSGPGTHLTVSAKPSPPVLSGPTVRATPEQTVNFTCTSHGFSPRNISLKWFKNGNELSASQTSVDPEDNNVSYSINSTTKVLLATGDVHSQVICEVAHVTLQGGPPLRGTANLSETIRVPPTLEITGSPSAGNQVNVTCQVNKFYPRHLQLTWLENGNMSRTEAASVFVENKDGTFNQTSWFLVNSSAHREAVVLTCQVEHDGQPAVSKNHTLEVSAPQKDQDTGQTPGPNDSNWTSIFIVVGVVCALLVALLIAALYLLRIRQNKAKGSTSSTRLHEPEKNTRETTQIQDNNDITYADLNLPKGKKSTPKANEPNNHTEYASIQARPPPVSEDTLTYADLDMVHLNRTPKQPAPKPEPSYSEYASVQVQRK
What is the function of this protein?
Immunoglobulin-like cell surface receptor for CD47.  Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane.  Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment.  May play a key role in intracellular signaling during synaptogenesis and in synaptic function.  Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin.  Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation.  CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.  Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization (By similarity).  Receptor for THBS1 (By similarity).  Interaction with THBS1 stimulates phosphorylation of SIRPA (By similarity).  In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RPOC_BARQU
Sequence: MNHEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPGRISTLLDLTLKDIERVLYFENYIVTESGLTSLKLHQLLSEEEYMLAIDEFGEDQFTAMIGAEAIYELLAGMELEKIANDLRVELSETTSELKQKKLIKRLKIVENFLESGNRPEWMIMKTIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIVRNEKRMVQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEHPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVSEKEPGEGMAFSDMGELHHALENKVVTLHTKIKGRVKNIDKDGKEVAKLYDTTPGRLIIGELLPKNPNISFDIVNQEMTKKNISKMIDQVYRHCGQKETVIFCDRIMQLGFSHACRAGISFGKDDMVIPDSKLRLVAETEALAKEYEQQYNDGLITQGEKYNKVVDAWGKCTDRVADEMMKRIQAVEFDPKTGRQRPMNSIYMMSHSGARGSANQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDAIISAVDCGTAKGLTMQPIVDAGQIVASLGQRILGRTALVDILHPVSGEVIVEGGVMIEETDVAKIEEAGIQSVQIRSALTCETRLGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSHLEASYEGTVEIRNRNVVHNSEGHLVVMGRNMVILIKDGSGKERVVHRISYGAHIFVDDGDVVKCGQRIAEWDPYTRPILTEVEGYVGFEDMIDGLSVTETADESTGITKRLVIDWRANPRGADLKPAIIIHADKKGEDIAKYKGGEARYMMSVDTILSVEPGAHVKAGDVIARLPMESAKTKDITGGLPRVAELFEARRPKDHAIIAEVSGTIQFGRGYKNKRRIIIEPNDETLEPVEYLIPKGKLFHFQEGDQIEKGDYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDSGYIPGDHVDRIELDEINDNLIAEGKRPASGNPILLGITKASLQTPSFISAASFQETTRVLTEAAVSGKIDTLQGLKENVIVGRLIPAGTGGTIAQIRRIAAVRDNLIVDERRKSSDSQVAKIMLTNMTTGATAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: XYLA_YERPG
Sequence: MQSYFNELEQVRYEGSQSTNPLAFHHYNPDEMILGKRMADHLRFAACYWHTFCWGGADMFGANAFDRPWQQPGDALALAKRKAKVAFEFFHKLNVPYYCFHDVDVSPEGASLQEYLNNFAVMTDVLAEKQAASGVKLLWGTANCFTHPRYGAGAATNPDPEVFSWAATQVFTAMNATRQLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDPQLGWDTDQFPNSVEENTLVMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKFAAKMIEDGQLDQIVAKRYAGWNSELGQQILQGKMSLEELSRYASQHNLNPQHQSGHQELLENKVNRYLFG
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.