PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_RHOBA
Sequence: MTMHIRWRGMELPSSLEVDRDSLTQTYGKFSAEPFERGFGASIGNSMRRVLLSSLVGSAVTQIKIRGAQHEFTTIPGVLEDVTDIVLNVKSLIVNSNTDSTRVITVERNTAGVVTGADVQTDADVEIINKDHVICTLTDDVPFMMEMVVETGRGYVPSTEHSSVDHEIGIIPIDAVFSPIVRVRYEVEATRVGQKTNYDRLNLEIWTDGTINPEMALTEAAKILRKHLNPFVQYRELGPSIFSAARGGAGSPEAQLEAKLNMTLADLRLSVRANNCLESENIMTVRDLVQRTEDSLLEVRNFGDTTLNEVREKLSQYGLHLGMRVPNQPLF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SPXM4_ORYSJ
Sequence: MVNFSNKLTKDQIPGWEEYYFNYKMLKGRVNEYTEQTKEGTQYRRRVLKDFSKLLDDEIEKIVLFMIEQQGLIAARLEDLGKRRARLQDIPLLQEITELREDYRSVGLDLVTLLKFVELNANAVRKILKKFDERLGYKFTDYYVRSRSNHPYSQLQQVFRHVGIGAVVGALSRNLSDLEERQGSYLNIYDQHPLAIPKDPIIDLITATADKLTNSTNFLRFLGQHALIAQADSTAGTEDEQHVGEDEYHLMSLVLNLANTFLYMVNTYIVVPTADGYATSLGAAATACGAVIGSMAVAQVFSSVYFSAWSNRSYFRPLLFSSVVLLLGNVMYAMAFDLGSLTILLLGRVLCGMGSARAVNRRYISDCVPPRIRMQASAAFVSASALGMACGPALAGLLQTNFSLYGLTINQITLPGWIMAFGWLVYLIWLWILFQEPDLGPDVKDFYEGSSSSTSTRYMEQEKMEQGFTEHLLPSEQDEEDDNGDEEHNETLSSSTTTLRPASSVASAYTLLTPSVKVQLLIYFMLKYAMEILLAESSVVTGYYFGWDIGTVSVFLAVLGLSVLPVNAIVGTYISNMFEDRQILVASEMALLAGVMLSFKLTVEYTAAQYVCSAVLTFVSAEVVEGVNLSLLSRVMSARLSRGTYNGGLLSTEAGTVARVVADGTITAAGLLAGEGRLLNATLLPALLVCVASIAATLSTYNSLFY
What are the official names of this protein?
SPX domain-containing membrane protein Os09g0521800.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UPPP_AERS4
Sequence: MTESYALFVAFVLGIVEGLTEFLPVSSTGHMIIVGHLLGFEGPKAATFEVVIQMGSILAVVAVFWRRLFGLIGIHFGQKPPQDHATLSLVHIILGMLPAVIIGLGIHSWIKANLFGPETVMYALVAGGILLIIAEKFRPTVRSETLDDISYKQAFGIGLFQCLALWPGFSRSGATISGGMLMGISRQAAAEFSFILAVPMMVAASGLDLYKSRDLLSMADFPMFAVGFITAFVVAMIAIKTFLALIRRLDFIPFAIYRFIVAFAVYLVFVA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TYSY_LACJO
Sequence: MATLEQPYLDLLSKIMSEGHDKEDRTGTGTRSLFGAQMRFDLNDGFPILTTKKIPFGLIKSELLWFLRGDTNIRFLLEHNNHIWDEWAFKNWVESNEYQGPDMTNFGLRSQQDPEFKRIYQEEMKKFDQKVLEDQTFAEKYGNLGDVYGAQWRHWQKREGGFIDQIQNVIDQIKKTPYSRRLIVSAWNPEDVPTSALPPCHVLFQFYVNDGCLSLQLYQRSGDMFLGVPFNIASYALLVNLVARETGLKPGEFIHTLGDAHIYKNHFNQVKELLNRSAYDAPMLWLNPDKKLVQDFEMKDIKLINYRHHGTIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATA_VIBPA
Sequence: MQMSKSFLLITVGLASTSLQAQTLTRDNGAPVGDNQNSITAGENGSVLLQDVHLIQKLQRFARERIPERVVHARGTGAHGEFVASGDFSDLTVSAPFTEKGKVTPVFVRFSTVIHSKGSPETLRDPRGFATKFYTEQGNWDLVGNNLPVFFIRDSIKFPDMVHSLKPSPVTNVQDPNRFFDFFSHEPSATHMLTWVYSNLGTPASYRTMDGFGVHAYKWINQQGDVNYVKFQWKSQQGIKSLRPNKVTEMQGKDFNHLTNDLYAAIGRGNYPKWDLYVKVLSPEALSKLDYNGLDATKVWLNVPDRKVGTMTLNRLPENFFLETEQSAFAPSNLIPGIEPSEDRLLQGRLFAYADTQLYRLGANLFQLPVNRPLTSVNNHNQNGLSNNAQLSNGDVNYEPSRKLNLAEDNQFKAVETKLVGTVQQKAISKPRDFYQAGVLYRSMNEQDRSDLIANLAGDLNKVIDKDIKATMVSYFYRADKEYGSRLAEATDTNLSQVKNKAMM
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: XERC_STAAT
Sequence: MNHIQDAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLELNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IVD_RAT
Sequence: MATAVRLLGRRVSSWRLRPLPSPLAVPQRAHSMLPVDDDINGLNEEQKQLRHTISKFVQENLAPKAQEIDQSNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASAAVGLSYGAHSNLCINQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMRLKAEKKGDHYVLNGNKFWITNGPDADVLVVYAKTDLTAVPASRGITAFIVEKDMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANILSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMACRQYVYNVARACDEGHITAKDCAGVILYTAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGGGTSEVRRLVIGRAFNADFR
What is the function of this protein?
Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway.  To a lesser extent, is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA.
What are the official names of this protein?
Isovaleryl-CoA dehydrogenase, mitochondrial, IVD, Butyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GPSB_STRTD
Sequence: MAKINLTPKKIYEQEFKTSMRGYDKTEVDEFLDDVIQDYTVYIALVKELQEENAKLKAKVTSASASRPAYASATSEPSHATGNIASASNYDILKRISRLEKEVFGKQIVE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: HME1B_XENLA
Sequence: EDPGTMGPGNPAPSPDSDTPSDSSKGSDSNPALLLVGNAAPPVHKKDSVVWPAWVYCTRYSDRPSSGPRTRKLKKKKSEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKASGMKNGLALHLMAQGLYNHSTTTVQEKEESE
What is the function of this protein?
Required for proper formation of the apical ectodermal ridge and correct dorsal-ventral patterning in the limb.
What are the official names of this protein?
Homeobox protein engrailed-1-B, En-1B, Homeobox protein en-1-B.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VTA1_BOVIN
Sequence: MAALATLPPLPPQFKSIQHHLRTAQEHDKRDPVVAYYCRLYAMQTGMKIDSKTPECRKFLSRLMDQLEALKKQLGDNEAITQEIVGSAHLENYALKMFLYADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYIHNCLKNGETPQAGPVGIEEDNVDVEEYEDAGATSLPTQPLQPSSSTYDPSNMPSSSYTGIQIPPGAHAPANTPAEVPHSTGVTSNTIQPTPQTIPAIDPALFSTVSQGDIRLTPEDFARAQKYCKYAGSALQYEDVSTAVQNLQKALKLLTTGRE
What is the function of this protein?
Involved in the endosomal multivesicular bodies (MVB) pathway.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies.  Involved in the sorting and down-regulation of EGFR (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein VTA1 homolog.
What is the protein family that this protein belongs to?
Belongs to the VTA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: UBIG_BRUSI
Sequence: MTETARTTIDASEIEHFSRIAAQWWDPQGKFRPLHKFNPTRLAYIKEKVCAKFNRDPNAPRPLEGLRFLDIGCGGGLLCEPMARLGATVIGADASATNIEVAKIHAAQSSLDIDYRATTAEALADAGEKFDVVLNMEVVEHVSDVDLFMSATSAMVKPGGLMFVATINRTLKAYGLAIIGAEYVLRWLPRGTHQYEKLVRPEELEAAFSKADLRLIDKLGVTYNPLADSWNRSRDMDVNYMVLAERPA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RNH2_ECOLU
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPSMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPP7B_BOTCO
Sequence: QNWPSPK
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent (By similarity).
What are the official names of this protein?
Bradykinin-potentiating peptide 7b, BPP-7b.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXK_ECOSM
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGICVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAIKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: END4_SALDC
Sequence: MKYIGAHVSAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFSEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPDIWAEEIAWLKAQQIAEAMA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: METE_AERPE
Sequence: MSHSYSVPKKFPTTVVGSYPKIGPASEAIKKRRAGEISEEEFHRIARESIRMVVEDYIWAGVDIISDGEQTREDMVVYFAERLEGYREGDWVRVFDNVYFRKPIVAGRVRWVRPMIIEDWEYARSISAGRPVKFIITGPYTMLEWSFDLHYGDRRELIFDLARAIRREIDEALARGAEYIQVDEPALSTRPFKEEAELLKEALDIIFKGVGAKRIVHICYGELERILPYILDYPVDQFDLEMKNSNFRLLPYLKEYGYDKEIGYGVIDVHSFQVESVGEVKEAIDRLMKMDIVGPEKVYVDPDCGLKRLPRDVARAKLKNMVEAARLAREEW
What is the function of this protein?
Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation.  The physiological methyl donor is unknown.
What are the official names of this protein?
Methionine synthase, Homocysteine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal MetE family.
Protein: SUHB_VIBCH
Sequence: MHPMLNIAIRAARKAGNHIAKSLENAEKIQTTQKGSNDFVTNVDKEAEAIIVSTIKSSYPEHCIIAEEGGLIEGKDKEVQWIIDPLDGTTNFVKGFPHFAVSIAVRFRGKTEVACVYDPMTNELFTAQRGAGAQLNNARIRVQPIKDLQGAVLATAFPFKQKQHSESFMKILSAMFVECADFRRTGSAALDLCYLAANRVDGYFELGLKPWDMAAGELIAREAGAIVTDFAGGTDYMQSGNIVASSPRGVKAILQHIRENGNSAILK
What is the function of this protein?
Part of the processive rRNA transcription and antitermination complex (rrnTAC).  The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNA polymerase (RNAP).  It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis.  This subunit may play a central role in organizing the structure.
What are the official names of this protein?
Nus factor SuhB, Inositol-1-monophosphatase, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_LACPL
Sequence: MSYASDVKKELTNLAVHRENAKAELMALIRMNGAISIANHHFILNIQTENPAIARRIYRLLKQFYDVDSELIVRRKMKLNKNNLYIVRLKTGTDMVLADLGILKDYQIVEVAPTEVLTDDAAVRSYLRGAFLAGGSVNNPETSRYHLEIYSLYEEHNHMISEMMNQYGLNSRTTDRRGGFITYIKEAEKIADFLSLVGATNAMLKFEDIRIMRDMRNSVNRLVNCENANMDKVANASSKQIENILLIDATVGLQQLPPKLQEVAVARLEHREVSLKELGTLVPGGPISKSGINHRLRKINQFAEQLQKDA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: ATP6_SALSA
Sequence: MTLSFFDQFMSPTYLGIPLIAVALTLPWILFPTPSTRWLNNRLITLQGWFINRFTQQLLLPLNLGGHKWAVLLTSLMLFLITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTAALGHLLPEGTPVPLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLMPIMPTVAILTSIVLFLLTLLEIAVAMIQAYVFVLLLSLYLQENV
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FAS1_ARATH
Sequence: MDEVSTVNENENRKTMIEPKKLNKRKREPTAIENLTSEEKESQISSLNLEMKGLFDYFREVMDKSKRTDLFSGFSECSSLNSMVALLMEEMSLPLSKLVDEIYLKLKEKTESVTMVAVKSAVVSVGQRVSYGVLNVDADVLEDDSESCLWCWETRDLKIMPSSVRGVLKLRRTCRKKIHERITAVSAMLAALQREETEKLWRSDLSKAAEKLGKILSEVDIRSFMDNMMQKNSSEMAEKDSKREEKLLLKQLEKNRCEAEKEKKRMERQVLKEKLQQEKEQKLLQKAIVDENNKEKEETESRKRIKKQQDESEKEQKRREKEQAELKKQLQVQKQASIMERFLKKSKDSSLTQPKLPSSEVTAQELSCTKHENEIGKVVQAIDNAFSTTCEATVDDIRREHFASWRQLGHLLSSSKKHWGMRRQPKSELFPKLKLSTNSGVTSDGEPNMEKQGDGCEENNFDGRQCKPSSSNRKKSRRVKQLLQFDKSCRPGFYGIWPSQSQVVKPRRPLQKDPELDYEVDSDEEWEEEEAGESLSDCEKDEDESLEEGCSKADDEDDSEDDFMVPDGYLSEDEGVQVDRMDIDPSEQDANTTSSKQDQESPEFCALLQQQKHLQNLTDHALKKTQPLIICNLTHEKVSLLAAKDLEGTQKVEQICLRALMVRQFPWSSLIEISINDIQDEDQEASKFSCSQSTPPSNSKAKIIPDSDLLTVVSTIQSCSQGINRVVETLQQKFPDVPKTKLRQKVREISDFEDSRWQVKKEVLTKLGLSPSPDKGGKRLPKTISTFFSKRCLPPSTKPQPAVEDAAERLENENA
What is the function of this protein?
Component of the chromatin assembly factor complex (CAF-1) involved in chromatin assembly following DNA replication and DNA repair.  Assembles histone octamers onto replicating DNA in vitro.  Required for several aspects of development, including seedling growth and leaf hair differentiation.  Plays a critical role in the organization of shoot apical meristem (SAM) and root apical meristem (RAM) during postembryonic development by facilitating stable maintenance of gene expression states.  Seems not required to maintain transcriptional repression of heterochromatic genes.  Involved in heterologous recombination.  May repress endocycle.
What are the official names of this protein?
Chromatin assembly factor 1 subunit FAS1, CAF-1 subunit FAS1, CAF-1 p150 homolog, Protein FASCIATA 1.
What is the protein family that this protein belongs to?
Belongs to the CHAF1A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDE6_DROMO
Sequence: MTDVSATTGRAGDRVSSTSSEVAVETTSQALTNGAAKEPLAAVTAEATATATVTATTTATVTATTTAATATMATAVISKQAKSECHSQSNNNQHVETAPSKQSSDSEASAPTTVSIPSANAKINSSSSGKTTATQQDVDEVARLFEEKPEAFEKWLTERAPPEALSRLHEFIESRKPHKRPSVTSDLFQQWMASPTVQQKSPRKLSNSSVHALPESRRHLMELDEGELFMELIRDVANELDIDVLCHKILVNVGLLTHADRGSLFLAKGTPNNRYLVAKLFDVTQTTALKDAVTRARAEEIIIPFGIGIAGMVAQTKQMINIKEAYKDARFNCEIDLKTGYTTNAILCMPICNYEGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEESHLEKIIEKPHQLQQQRTPRAIMSGDSFEEKQNMRNRFTVLFELGGENHAANVSRPSINDLSHSTLAQIAQFVATTGQTVNICDVQDWVREHNQIRAESEIDSTQAILCMPIVNAQKTVIGVAQLINKASGLPFTESDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLAQDVIAEAEAYNLYSFTFTDFDLVDDDTCRAVLRMFMQCNLVSQFHIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHRVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMGLTWIDHDTIDKPVEEFAGCADEEIKDIEFTVTTLNCNQHGGSAGGGEDTHTPEHQRSSSRLSIKKTGALGKVVRSKLSKTLYNSMDGSKPKTSLKLLESHVSEDMDDKSPTSPSQPHSGSVGRMSASSSTSSAGTVDKSKKRSKLCALL
What is the function of this protein?
Has a role regulating cGMP transport in Malpighian tubule principal cells.
What are the official names of this protein?
cGMP-specific 3',5'-cyclic phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: BCCP_HAEIN
Sequence: MDIRKIKKLIELVEESGITELEVQEEEGTVRISRAAPVIAPAAVQYAAAPVVAPTPAAAPAQVPAAATTAPAASDELSGHLVRSPMVGTFYRSPSPEAKAFVEVGQSVKVGDALCIVEAMKMMNRIEADKAGVVKAILINDGNAVEFDEPLIVIE
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxyl carrier protein of acetyl-CoA carboxylase, BCCP.
Protein: VDR_RAT
Sequence: MEATAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIMKRKEEEALKDSLRPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMDGSTGSYSPRPTLSFSGNSSSSSSDLYTTSLDMMEPSGFSNLDLNGEDSDDPSVTLDLSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNEIS
What is the function of this protein?
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:17227670).  Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity).  The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity).  Plays a central role in calcium homeostasis (PubMed:17227670).  Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites (By similarity).
What are the official names of this protein?
Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes mainly to the nucleus. Translocated into the nucleus via both ligand-dependent and ligand- independent pathways; ligand-independent nuclear translocation is mediated by IPO4.
Protein: CLPP_CAMJD
Sequence: MFIPYVIEKSSRGERSYDIYSRLLKDRIIMLSGEIHDELAASIVAQLLFLEAEDPTKDIYLYINSPGGVITSGFSIYDTMNYIKPDVCTICIGQAASMGAFLLSCGAEGKRFALPNSRIMIHQPLGGARGQATDIEIQAKEILRLKTILNDILAKNTKQKVAKIAKDTERDFFMSAQEAKEYGLIDKVLEKSFK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_KOCRD
Sequence: MSVPKIVLFYVFTPLADPEAVKLWQLNLAQRSGVKGRIIVSEQGINATVGGDIHDVKAYVRGLKEYAPFQHADIKWSDGAGDDFPRLSVKVRPELVTFDAPDLIRVTEHGVEGGGTHLTPHEVHELVERRGEDVVFFDGRNQLEAEIGRFRGAVVPRTETTRDFLRELDSGAYDHLKDKALVTYCTGGIRCEVLSGLLRNRGFRDVYQLDGGIVRYGEAYGDRGLWDGSLYVFDERRHMEFSLSARSLGRCVQCGEATPRYVNCANQQCRRLFLCCETCTGAGARTRCADCVPVAA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.