PharMolix/UniProtQA huggingface dataset:
Protein: LFTR_AGRFC
Sequence: MAGRRSRNNDITVDILLRAYSAGLFPMADSADDPELFWVEPEIRGIIPLDDFHVSKSLAKAMRKKPFAIRFNTAFEDVMAGCAAEAADRPSTWINATIRRLYTELHQIGHAHSVEAWEGDELVGGLYGVSLGAAFFGESMFSRRTNASKICLVHLVERLNAKGFVLLDTQFTTEHLKTFGAIDVPKLDYARMLDLAVNRPSLQF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP2_ARTBC
Sequence: MAAQAAPELAKLDLNKNTGSVEANAVSAGGSEKEEAENEGDSDDDRDDEQAGGSAEVNAEKKKKKKRPKKKKKTAKVQSSPPRIPLTTLFPNSNFPEGEIVEYLNENSYRTTNEEKRHLDRMNNDFLTEYRQAAEIHRQVRQYAQKELIKPGATLTDIAEGIEDGVRHLTGHMGLEEGDSLVAGMGFPTGLNINHCAAHYSPNAGNKVVLQHGDVMKVDFGVHINGRIVDSAFTVAFDPVFDPLLTAVKEATNTGIKEAGIDVRMSDIGAAIQETMESYELELNGTSYPIKAIRNLNGHTIGQYEIHGGVNGKSVPIVKGGDQTKMEEGETYAIETFGSTGKGYVRDDMETSHYAKVPNAPSVPLRLSSAKNLYSLINKNFGTLPFCRRYLDRLGQEKYLLGLNNLVSSGLVDAYPPLCDVKGSYTAQFEHTILLRPNVKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRE5_ARATH
Sequence: MSNRRSRQTSNASRISDDQMIDLVSKLRQFLPEIHERRRSDKVSASKVLQETCNYIRKLHREVDNLSDRLSQLLDSVDEDSPEAAVIRSLLM
What is the function of this protein?
Atypical and probable non DNA-binding bHLH transcription factor that integrates multiple signaling pathways to regulate cell elongation and plant development.  May have a regulatory role in various aspects of gibberellin-dependent growth and development.
What are the official names of this protein?
Transcription factor PRE5, Basic helix-loop-helix protein 164, AtbHLH164, bHLH 164, Protein PACLOBUTRAZOL RESISTANCE 5, bHLH transcription factor bHLH164.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_PSEU2
Sequence: MRVILLGAPGAGKGTQAKFITEKFGIPQVSTGDMLRAAVKAETELGLKAKSVMDSGGLVSDDLIIGLIKDRLAEPDCANGVLFDGFPRTIPQAEALLNAGLEIDHVLEIAVDDEEIVKRMSGRRVHEGSGRIYHTIFNPPKVEGIDDVTGEPLLQRKDDVEETVRHRLSVYHAQTKPLVEFYSKLEAKNGKPKCSHIPGVGSVEDITAKVLKALS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_MESM1
Sequence: MANIKSKEKRILTNEKARVRNAAMKSHVRLAIKKAKRAIEEKNENVEQLLKDAHKVINTSVSHGVFHRNNAARKSSRLDAYAFKIQNKTAN
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HISZ_PSEPF
Sequence: MATVDRWLLPDGIEEVLPPEAARIEVARRQVLDLFQSWGYEFVVTPHIEYLESLLTGAGQDLDLRTFKVIDPQSGRQMGFRADITPQVARIDAHTLRREGPSRLCYAGSVLHAQPRALSSSRSPIQLGAELYGDASPSSDVEVISLMLAMLQLADVPDVHMDLGHVGIYRGLAQAAGLSGEVEQQLFDALQRKAIDEVITLTEGLPADLSGMLRALVDLCGGREVLSAARERLANAPAPVLAALEDLLAIAERLSVRFPELPLYFDLGELRGYHYHTGVVFAVFVPGVGQSIAQGGRYDDIGADFGRARPATGFSTDLKTLVTLGRAEIELPSGGIWMPDSTDAALWQQVCQLRSEGQRVVQALPGQPLAAARDADCDRQLIQQNGLWQVSPLAS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRDA_ECO57
Sequence: MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQIVRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTLDALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKGYKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVLHGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKPYVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIHSGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAERLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAENPAVAAAEDH
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall.
What are the official names of this protein?
Peptidoglycan D,D-transpeptidase MrdA, Penicillin-binding protein 2, PBP-2.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. MrdA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SEN22_ARATH
Sequence: MAPRWKWKGAEAKALAEPISKSVSELQLSLAETESSGTLSSCNVLLAVEPEQAELLDRCCFGRLVLSAEKIKKWIQLSFEEAFFLHYNLKCIKISLQGRCLENEVDTWLYMKSKRPNFPMFFKAYSHLRSKNWVLRSGLQYGVDFVAYRHHPSLVHSEYSVLVQSGDSDRLRVWSDIHCAVRLSGSVAKTLLTLYVNGNFKGEDVNLLVCLENFTVEEQTISRWSPELSREDQSTNSKQHVPNVSNLNTL
What is the function of this protein?
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  Probably carries the active site for 5'-splice site cleavage (By similarity).
What are the official names of this protein?
tRNA-splicing endonuclease subunit Sen2-2, tRNA-intron endonuclease Sen2-2, AtSen2.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SAM50_SCHPO
Sequence: MTEQFESTSFPSDIPAVNEESKLSAEETFKSLSEILAENSTLPVGISSIRVTGAHHTRPSFIRKVLKTCLDTSKPAKSRSLLETLNAIQETTGNLMAFNVYETANIKIDRASSSVSGDDDLDVTIQVKEKPRLYVETGTDVGNVEGNVHANVLARNVFGGAELLSGNVSYGTRNRSTMSVNFETPVNADPKTRLRFNGHSNLRDNKSISSHDLLTKGITLSLQHQDLWSGEHLLSQNLLWRQVTHLTEYASPSVRLEAGDSLKQSLSYTYTRDTRDHLMIPTKGDYVRQTLELAGFGFLPGDASFLKSEFWGQKAVALNSSRSVSLSLSARIGALHSLNKKQVSLCDRFMLGGSTSLRGFSEDRIGPKDGRDSLGGTAYMAFSMSLLFPLPKVDASKPFRLQLFANAGGLSNLTSPNPCGTYKSILSKPCISTGLGLVYATPAARFELNFTLPIATTEKDIGRKGLQFGAGIDFM
What is the function of this protein?
May be required for the assembly pathway of mitochondrial outer membrane proteins.
What are the official names of this protein?
SAM50-like protein SPAC17C9.06.
What is the protein family that this protein belongs to?
Belongs to the SAM50/omp85 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: SPLB_STAAT
Sequence: MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
What is the function of this protein?
Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.
What are the official names of this protein?
Serine protease SplB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: CPS1_MARVU
Sequence: MASTPTLNLSITTPFVRTKIPAKISLPACSWLDRSSSRHVELNHKFCRKLELKVAMCRASLDVQQVRDEVYSNAQPHELVDKKIEERVKYVKNLLSTMDDGRINWSAYDTAWISLIKDFEGRDCPQFPSTLERIAENQLPDGSWGDKDFDCSYDRIINTLACVVALTTWNVHPEINQKGIRYLKENMRKLEETPTVLMTCAFEVVFPALLKKARNLGIHDLPYDMPIVKEICKIGDEKLARIPKKMMEKETTSLMYAAEGVENLDWERLLKLRTPENGSFLSSPAATVVAFMHTKDEDCLRYIKYLLNKFNGGAPNVYPVDLWSRLWATDRLQRLGISRYFESEIKDLLSYVHSYWTDIGVYCTRDSKYADIDDTSMGFRLLRVQGYNMDANVFKYFQKDDKFVCLGGQMNGSATATYNLYRAAQYQFPGEQILEDARKFSQQFLQESIDTNNLLDKWVISPHIPEEMRFGMEMTWYSCLPRIEASYYLQHYGATEDVWLGKTFFRMEEISNENYRELAILDFSKCQAQHQTEWIHMQEWYESNNVKEFGISRKDLLFAYFLAAASIFETERAKERILWARSKIICKMVKSFLEKETGSLEHKIAFLTGSGDKGNGPVNNAMATLHQLLGEFDGYISIQLENAWAAWLTKLEQGEANDGELLATTINICGGRVNQDTLSHNEYKALSDLTNKICHNLAQIQNDKGDEIKDSKRSERDKEVEQDMQALAKLVFEESDLERSIKQTFLAVVRTYYYGAYIAAEKIDVHMFKVLFKPVG
What is the function of this protein?
Involved in the biosynthesis of labdane-type diterpenoid including marrubiin and other labdane-related furanoid diterpenoids with potential applications as anti-diabetics, analgesics or vasorelaxants (Probable).  Terpene synthase that produces peregrinol diphosphate from geranylgeranyl diphosphate (GGPP) (PubMed:24990389).
What are the official names of this protein?
Peregrinol diphosphate synthase CPS1, chloroplastic, (+)-copalyl diphosphate synthase 1, MvCPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PETD_SYNS3
Sequence: MHILKKPDLTDPKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACIVGLSVLDPAMLGDKADPFATPLEILPEWYLYPVFQILRVVPNKLLGIALQTLVPLGLMLIPFIESFNKFQNPFRRPIAMAVFLFGTATTIYLGIGAAMPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CLPX_STRPM
Sequence: MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGKSKPVLETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ATP8_EMENI
Sequence: MPQLVPFFFVNQVVFAFIVLTVLIYAFSKYILPRLLRTYISRIYINKL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RUVA_FRATT
Sequence: MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFVVREDAQQLYGFKSKVDKKVFQELIKVNGIGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKTAERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPTSVVLANSIFNESVDALLALGYKQKDAEKMARSAMGDATTVAEVIRKALQGSIKSKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NADD_BUCAI
Sequence: MKKLCAIFGGNFDPIHYGHINLAEKLAKDISIKKIILLPNNYPPHRNKTQTSISDKIKMIKLAIHNNPLFEISYLETKKNNIFYTIDTLKKIRKKISHLEPLCFIIGEDNLQTFYLWKNWREILLYSHLLIYPRKHKKQKNDELEKWIHSNTVYDCNLLHKQPCGLIFFSHAPCINISSSRIRKNYFYGKNSHSLLPSIVNNYILLKKLYYTNQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RBMX_MOUSE
Sequence: MVEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSFESGRRGLPPPPRSRGPPRGLRGGRGGSGGTRGPPSRGGHMDDGGYSMNFTMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVRSSSGLGGRAPVSRGRDGYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSREYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYSDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGLPPSMERGYPPPRDSYSSSSRGAPRGGGRGGSRSDRGGGRSRY
What is the function of this protein?
RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes.  Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs.  Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter; may thus be involved in tumor suppression.  When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter.  Associates with nascent mRNAs transcribed by RNA polymerase II.  Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection.  Can either activate or suppress exon inclusion; acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2.  Represses the splicing of MAPT/Tau exon 10.  Binds preferentially to single-stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation; probably binds RNA as a homodimer.  Binds non-specifically to pre-mRNAs.  Also plays a role in the cytoplasmic TNFR1 trafficking pathways; promotes both the IL-1-beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment.
What are the official names of this protein?
RNA-binding motif protein, X chromosome, Heterogeneous nuclear ribonucleoprotein G, hnRNP G.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes in numerous small granules in the nucleus (By similarity). Component of ribonucleosomes.
Protein: DRE1A_ARATH
Sequence: MNSFSAFSEMFGSDYESSVSSGGDYIPTLASSCPKKPAGRKKFRETRHPIYRGVRRRNSGKWVCEVREPNKKTRIWLGTFQTAEMAARAHDVAALALRGRSACLNFADSAWRLRIPESTCAKDIQKAAAEAALAFQDEMCDATTDHGFDMEETLVEAIYTAEQSENAFYMHDEAMFEMPSLLANMAEGMLLPLPSVQWNHNHEVDGDDDDVSLWSY
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates cold-inducible transcription.  CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation.
What are the official names of this protein?
Dehydration-responsive element-binding protein 1A, Protein DREB1A, C-repeat/dehydration-responsive element-binding factor 3, C-repeat-binding factor 3, CRT/DRE-binding factor 3, Cold resistance-related AP2 transcription factor.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA_I05A1
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERSESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKEDRFIEIGVTRREVHTYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEEKFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIRCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDVSDLRQYDSDEPESRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAVGQVSRPIFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNNLYASAQLEGFSAESRKLLLITQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLAHVLK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: TRUB_BACVZ
Sequence: MVNGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGVLPICVGRATKIVEYVTDKSKTYDAEITLGFSTSTEDQTGETVSVKPVKEPLKEADIKAVLDELKGPQEQVPPMYSAVKVNGKKLYEYARAGIEVERPKRNITIEDIALTSPVTYNEDTASFRFTVTCSKGTYVRTLAVTIGEKLGYPAHMSHLIRTASGDFSLDECFTFEELEQQVSDGTVAEHAVPIDRALNHLPKWVISDTLAKKAENGSVFDIPAEFSAMTADARIAVCTEDGECVAIYMPHPSKKGLLKPAKVLMQKSEQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ABTB1_HUMAN
Sequence: MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
What is the function of this protein?
May act as a mediator of the PTEN growth-suppressive signaling pathway.  May play a role in developmental processes.
What are the official names of this protein?
Ankyrin repeat and BTB/POZ domain-containing protein 1, Elongation factor 1A-binding protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUA_HAEDU
Sequence: MFKKTVLTLAMLGVTTVANADVLTSIKPLGFIANAITDGVTETKVLLPVTASPHDYSLKPSDIEKLKSAQLVVWVGDGLEAFLEKSIDKLPKEKVLRLEDVPGIKMIVDATKKKDHDHHDHDHDHDHDHDHEHIHGHHHDKDWHIWFSPEASQLAAEQIAERLTAQLPEKKAKIAENLAAFKANLADKSNEITQQLQAVKDKGYYTFHDAYGYFERAYGLNSLGSFTINPTIAPGAKTLNAIKENIAAHKAQCLFAEPQFTPKVIDSLSKSTAVKVGQLDPLGAKVKLSKTAYPQFLQAIADEFSQCLTQ
What is the function of this protein?
Involved in the high-affinity zinc uptake transport system.
What are the official names of this protein?
High-affinity zinc uptake system protein ZnuA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PCR4_ARATH
Sequence: MGRPGSQPNEAQPPPVQVQPTVNRDNQVHSQNGAIGQANIQTGRPVNNQTQNLWSSDLFDCMNDSENAVITCLAPCVTLGQIAEIVDEGATPCATGGLLYGMIFFIGVPFVYSCMFRAKMRNKYGLPDAPAPDWITHLFCEHCALCQEYRELKHRGFDPNIGWAGNVQAQQPVMSPPTGQRMMG
What is the function of this protein?
May be involved in heavy metals transport.
What are the official names of this protein?
Protein PLANT CADMIUM RESISTANCE 4, AtPCR4.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL7_MYCLE
Sequence: MSKLSSDELLDVFKEMTLLELSDFVKKFEETFEVTAAAPVSVAVAGAPAAGEAGEAAEEQSEFDVILESAGDKKIGVIKVVREIVSGLGLKEAKDLVDGVPKLLLEKVAKEAADDAKAKLEATGATVSVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: HIS1_SYNC1
Sequence: MSDYITFALPKGRIMRDSMELFAKIGITCPEMSGDSRKLVFENPETKFRFMAVRATDVPTYVEYGCADLGVVGKDTLLEQGKDLYEPLDLKFGYCRLVVAEPGELSRDEDPADWSNIRVATKYPNITERYFAERGVQVELIKLYGSIELAPLVGLAERIVDLVSTGATMRDNGLVEVETIGEITSRLIVNRASLKTKHQRITRIIQDLERVLAEDAGND
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_MYCCT
Sequence: MKNNYKSLVIVGSQWGDEGKGKITDYFSQKADAVVRFAGGDNAGHMIEFNNKRHKVTIIPSGVFNPKVKNIIGNGTVINLKSLVNEIKRLNESNISTDNVYISDRAHLIFDWHTLIDQLQEENRKENKIGTTKRGIGPSYADKAARYGIRICDLKSPNFKEIFKENLDYHNEIITKVYNHKPLDFDQIYNELLTNYQLIKNNIIDCGYEVSNLINENKFVLFEGAQGVLLDIDHGTYPFVTSSNCSANNASIGTGIHAKQIQKVIGIVKAYNTRVGSGAMPTEIKTELANKLRERGREYGSNTGKPRRIGWLDLVALKYAIRVGGIDQLFLTLFDVLDTEEKIKICTAYKLDNQIIHSIPANENDFKRCEPIYEELDGWNEDITKITSFEQLPINAQNYIKRIQEIVNVPFLGFSVGPDRKQTILIKGEFDD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.