PharMolix/UniProtQA huggingface dataset:
Protein: NDK_XANOR
Sequence: MALERTLSIIKPDAVAKNVIGEIYSRFEKAGLKVVAAKYKQLSRREAEGFYAVHRERPFFNALVEFMISGPVMIQALEGENAVAAHRDLLGATNPKDAAPGTIRADFADSIDANAAHGSDSVENAANEVAYFFAATEVVSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPCB_COCH5
Sequence: MAVISLLQGLSVGQQIGTAAAISVFVLTSIVVYGCYLHPLSHVPGPFLAKFSPIWGMRALYRMKFNSELQALHEKYGPVVRVAPNEVSFATLEAETAIYANQEDGRFSKAGTFLTLFSDLVLNAPTLITIPDPALHKRLHKVIQQAFTPQALASQEPIQKLHIEKAIPDFDETADKGYHIDLADKLETMFWEIIGDLAFGEPLMAGKRPTYEKLKQLGKGSMPMVEALSFMLVMPGVAPTLEMARSFLSAMPMSSQLSKLVPSTKLRDCVERKDGREDFLSAIMGSEKQGLTLDADAFFSNAMGLTLAGYQTTATTLASTFYHVLRYTDAYKTLCTEIRSAFNDEAEITGERLARLPFLNACIRETLRLLPPANGKTAQRTAPSCTIADTYIPAGTIVSADLYTIQRSPKYFVDPARFHPERWLEDAEKNGFNGDNRSASRPFLIGSRACIGRHMAQQSIRLIMATLLWRYDFELLDPDGFIWERDAGSSLIYTDYKLPVHVKRFQ
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of terpestacin (PubMed:29185768).  The bifunctional terpene synthase tpcA converts isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) into the sesterterpene preterpestacin I (PubMed:29185768).  The C-terminal prenyltransferase (PT) domain of tpcA catalyzes formation of GFPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GFPP into preterpestacin I (PubMed:29185768).  The cytochrome P450 monooxygenase tpcB then hydroxylates preterpestacin I to yield 24-hydroxypreterpstacin I (renamed as preterpestacin II) whereas the cytochrome P450 monooxygenase tpcC further hydroxylates preterpestacin II to yield 16,17-dihydroxypreterpestacin II (renamed as preterpestacin III) (PubMed:29417814).  Finally, the FAD-dependent monooxygenase tpcD converts preterpestacin III into terpestacin (PubMed:29417814).
What are the official names of this protein?
Cytochrome P450 monooxygenase tpcB, Terpestacin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: NCL_ARATH
Sequence: MRFRSLISLLFLLFFTSSAYARFVSLNPSSTSLISDGIDGGSNLAGSGSVIKSVVSAPAEEKEEACEQTYGFMPCTKTALGNVFLILVYGFLMFTAATYLSAGSELLLEILGPGIVGGLFLPMLGALPDAMLIMVSGLSGDAATAQSQVSVGMGLLAGSTVMLLTVIWGTCTVVGKCDLRDSIAVNNQDTKGFHLKDSGVTVDIWTSYAARIMAISVIPFVIVQLPQMLGSTSGRQLSVLIALILSVLMLISYCVYQVFQPWIQRRRLAFAKHKHVISGILRHLKQHALGRLLDDEGQPDEHVIRKLFLTIDANNDGHLSAAELKALIIGISFEDIDFDKDDAVGKVLQDFDKTLDEQVDQEEFVRGIKQWLIQAMGGAPSGPEAGPRTMKFLDNFHVQTKREHALLGDNENGENDEEGGEVADPKWITIKAALLLLLGAAIAAAFADPLVDTVNNFSAATGIPSFFISFIALPLATNSSEAVSAIIFASRKKIRTASLTFSELCGGVTMNNILCLSVFLAIVYVRGLTWNFSSEVLVILIVCLVMGGFASFRTTYPLWTCFIAYLLYPFSLGLVYILDYWFGWS
What is the function of this protein?
Possesses sodium/calcium exchanger (NCX) activity when expressed in a heterologous mammalian CHO-K1 cell system (PubMed:23148213).  Does not possess cation/proton exchanger (CAX) or sodium/proton (NHX) activity when expressed in a heterologous yeast cell system.  Has the ability to bind calcium in vitro.  Participates in the maintenance of calcium homeostasis (PubMed:23148213, PubMed:26296956).  May play a role in auxin response, diurnal rhythm and flowering time (PubMed:26296956).  Involved in salt stress response (PubMed:23148213).
What are the official names of this protein?
Sodium/calcium exchanger NCL, Na(+)/Ca(2+)-exchange protein NCL, Protein NCX-like, AtNCL.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: CYSD_ZYMMO
Sequence: MQEERLTHLRQLEAESIYIIREVAAEFGNPVMLYSIGKDSSVMLHLARKAFFPGTLPFPLLHVDTGWKFREMYEFRDRTAKEYDFNLLVYKNPEGEALGINPFIHGSAKHTDIMKTEGLKQALDKYGFDAAFGGARRDEEKSRAKERIYSFRDKFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTELDIWQYIYLENIDIVPLYLAAKRPVIERDGMLMMVDDDRIDLKEGEKVEERMVRFRTLGCWPLTGAVESQAQTLPEIIEEMLVSTTSERQGRVIDRDQSGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: CL2D6_RAT
Sequence: MPSSAHLQDSPPLLSRTLTQNEGQTSLRQSSSCGPSATSASESLSGYTESRIPHSEMLQEKFHGIILPESPAKLLCCCAVIVVLSVAVVALSVALSVKKTPQISTVKTYAACPRNWIGVGNKCYYFNETARNWTFSQTLCKEQEAELARFDTEEELNFLRRYKGSPGCWIGLHRESSAHNWTWTDNTAYNKLLPIRGVEKHGFLSDNGISSSRDYIKRNSICSKLNSYTSQCQ
What is the function of this protein?
Lectin-type cell surface receptor.
What are the official names of this protein?
C-type lectin domain family 2 member D6.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: Y163_THESQ
Sequence: MIITTTEQVPGYRVKEILGVVCGNVVMSKHLGKDIAAAFKTLAGGEIKGYTEMLTEARNIALERMIKEAEKLGADAVIGFRYSSSTIMSGAAEILAYGTAVKLEKI
What are the official names of this protein?
UPF0145 protein TRQ2_0163.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RRT14_LODEL
Sequence: MASFTSNASKHQAELTVNRMFADILHTQPLRSAKSTTSNKSKSASKFGNDRKALSMPTPLSSTQILSQQLQPQLQQTRLSLKTGKSSQNNNKVKKLLKKKHEQDKKFQKFIKYSMIKNKMSTDPESLTLEEHKYLKKLAKRNINALQKYSKIDDFEIEQEMSSVKNELLKDLAPKKQTRLRKKLAIPAKKGSARSNANNQINDFDYERKLQKGLISAPGLTPGLAPVDYDDDEEEEEEED
What is the function of this protein?
Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription 14.
What is the protein family that this protein belongs to?
Belongs to the RRT14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AMT3_SCHPO
Sequence: MLNEPNALLRRDANSTIATVTELFPNEYSNADIAYVLLSTVVVFTVTPGIALYYAGMVRKNSALSILTQSFLVTAVVFIQWYLFGYSLACSSGSSFYGTLWQGGMNHLWLEPYIPGSTIPAIVYFPFGGLFAVATAQLFAGAMAERGRLIPSLVISFLYITLVYCPQAYWTWAPNGWLYTLGALDFAGGGPVHISSGFAALAYSLCLGRRIVVDEPDRPDSIRSTDNADLPSSSQNNCKANWKRWFGFKSVSWKNSFGRGKIAHNPPHDAGMVYIGVVLIWFAWLCFNSGTLLTVNIRTAYIMTNTLISSSFGALTWAIIDYIRYRKFSTIGICEGAIAGLVGITPACGFVFPWGAAAGGIVPALVCNFLHDLNEWIGVDETLRVFNLHGIGGIVGSIVLGVVAHPDVAASDGATVIDGGWAVHHWKQMGYQFAGFTSVAAWSFVITAIICLLVDLVPGLHIRASFEEELRGMDFVELEEQLPGQTLESKPMIIYAQEMDEPVTQGSNIKQEKQDEF
What is the function of this protein?
Transporter for ammonium to use as a nitrogen source.
What are the official names of this protein?
Ammonium transporter 3, Ammonium transporter mep3.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: ATPF2_BRUA1
Sequence: MDATFWAFIALVIFVAIVVYMKVPGMIGRTLDERADRIKKELEEARTLREEAQQLLAEYHRKRKEAEKEAGDIVASAEREAKALLEEAKRATEEYVARRNKLAEQKIATAETDAINAVRASAVDLAVAAAGSILAEKVDAKADGNLFNDALAQVKSHLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: IQUB_MOUSE
Sequence: MSDPEEERVADSTAHYEEAGKVISIPRPSDEAEGSDVMPEQDDEVQELTTESEENVERHSEFSLSTPKSDDSKPREEVTSLGSASGSQDQDYRLLDYQKGEDDELLFLHKIKAIKETLQTSVRESIATVKIVLIPAGQEIIMPFRVDAPFRFLKEHFAHLLHIPHYVLQITHEGIIVGNNESLIQYGIKPQEIVQVEVFSTLPDQYPVRRIEGLSEGSQIITVTIQTSIDRYEEVAVEIIKSDFHKPFLGGFRHKITGLEYHNAGTQTVPRKIPEKDNLFCRDTQTVFQKKKLQQTTNTTSTQMTKIGVYVSNMTDKLLKPGNYFSAAEYHARRLHAVIVIQTSYRRWHAKRYVESLRKQKKLRLEWEEEQELLKIQEKEEWIRMDYYRRHNPKTTEDFELLYNALELWRQEEVEQICHYSSEAERKAALCELLEKETQMIASIGRHRSAARMERQDAAIQAFLDKCSAPNVWRRGDGKTIEMDTQFTIRARELQSIYKCILLKDLSQDERLDILLTLKHTVKEHECKLTQEILELIDREVDLMMRGVKPHNLEGLRKRITTLFIHYIKTPLFNPEVAKYLKVPQDPLKFYDTIYFCHSCQNYLPSVEFSVSPTSHRVYRCRHCINLENETQRRESFLKYKCLLQRLYYSEADYGDNSQIAFLMQLQDIKYLTENIWASQSALSAWDDLNDLVMVRWDKHVEWSPWNCILLTKDESTAHLRLPSIEKGYGHHFVHKIKHKHILAKNYFSQIPTLASLILNDDEVEDIRSKHSTKSPPKIIITRRIQPH
What is the function of this protein?
Anchors the radial spoke 1 (RS1) complex to the A microtubule of outer doublet microtubules in axonemes (PubMed:36417862, PubMed:36355624).  The triple radial spokes (RS1, RS2 and RS3) are required to modulate beating of the sperm flagellum (PubMed:36417862, PubMed:36355624).  May play a role in inhibiting signaling via MAPK1/ERK2 and MAPK3/ERK1 (PubMed:36355624).  Additionally, may play a role in the functioning of cilia (PubMed:21289087).  Not required for the functioning of tracheal or ependymal cilia (PubMed:36417862).
What are the official names of this protein?
IQ and ubiquitin-like domain-containing protein.
Protein: AROC_NITOC
Sequence: MSGNTLGKLFTVTTFGESHGPALGCIVDGCPPGLALCETDIQIDLDRRRPGKSRHTTQRREPDQVQILSGVFEGKTTGTPIGLLIENVDQRSRDYDKIKEQIRPGHADYTYLQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAERHGVKIRGYLAQLGPIRAERFDWEIVEKNPFFCPDPDKISELEAYMDALRKEGDSIGARINVVATGVPPGLGEPVFDRLDADLAHALMSINAVKGVEIGVGFAAVTQKGTDHRDPLTPEGFLSNHAGGVLGGISTGQDILASIALKPTSSLRLPERTINCRGESAEVVTTGRHDPCVGIRATPIAEAMAALVLMDHLLRHRAQNMDVQPSLPSIPAYPGGGG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: LHSR1_CHLRE
Sequence: MAMMMRKAAAVPASSRRSVAVNSVSGKRTVSGKAGAPVPEDVLAYAKTLPGVTAPFDNVFDPAGFLATASVKDVRRWRESEITHGRVAMLAALGFIVGEQLQDFPLFFNFDGRVSGPAIYHFQQIGQGFWEPLLIAIGVAESYRVAVGWATPTGTGFNSLKDDYEPGDLGFDPLGLKPTDPEELKTLQTKELNNGRLAMIAIAAFVAQELVEQTEIFEHLVLRFEKEVILELEDVERDLGLPLTPLPDNLKAI
What is the function of this protein?
Required for non-photochemical quenching (NPQ), a mechanism that converts and dissipates the harmful excess absorbed light energy into heat and protect the photosynthetic apparatus from photo-oxidative damage (PubMed:27335457, PubMed:29555769, PubMed:30782831).  Is able to sense luminal acidification of the thylakoid membranes, which occurs along with elevated electron flow caused by excess light, and to induce a large, fast, and reversible pH-dependent quenching in LHCII-containing membranes (PubMed:27335457).  Mediates excitation energy transfer from light-harvesting complex II (LHCII) to photosystem I (PSI), rather than photosystem II (PSII), at low pH, which mimics the acidified lumen of the thylakoid membranes in high light-exposed chloroplasts (PubMed:29555769, PubMed:30782831).  Activates PSI-dependent fluorescence quenching in addition to dissipating excitation energy in LHCII to avoid photooxidative stress under excess light (PubMed:29555769, PubMed:30782831).
What are the official names of this protein?
Light-harvesting complex stress-related protein 1, chloroplastic, Chlorophyll a-b binding protein LHCSR1.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TX21_HADIN
Sequence: SNRWNLGYGIPHKQVKLPNGQLCKEPGDSCSKRDECCKADDQKTYSSGCAQTWSAMEGGFVRECYICAVESSMC
What is the function of this protein?
Probable neurotoxin with ion channel impairing activity.
What are the official names of this protein?
U21-hexatoxin-Hi1a, U21-HXTX-Hi1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FEMB_STAA8
Sequence: MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDIVPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKVLVPLAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDHDQHELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKYWLFTTLDKLRKKLKK
What is the function of this protein?
Catalyzes the formation of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  Adds glycines 4 and 5 of the pentaglycine bridge, using glycyl-tRNA(Gly) as donor.  Involved in resistance to methicillin.
What are the official names of this protein?
Aminoacyltransferase FemB, Factor essential for expression of methicillin resistance B, N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_BRADU
Sequence: MPTINQLIAQPREVQKSRKKVPALQQSPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHILRGVLDTQGVKNRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PGK_NOCFA
Sequence: MAVKTLQDLLNEGVEGRGVLVRSDLNVPLDDNGQITDPGRIIASIPTLKALVEAGAKVVVTAHLGRPKGEPDPKFSLAPVAAKLAELLGRNVQLAGDVVGYDALSRSEGLTDGDVLLLENVRFDPRETSKDEAERGKLAAALVELVGEDGAFVSDGFGVVHRKQASVYDVAKLLPHYAGTLVAAEVDVLAKLTDNTERPYAVVLGGSKVSDKLAVIEALAPKVDTLVIGGGMCFTFLAAQGLSVGSSLLQEEMIDTCKGLLERYADVIHLPRDVVVADSFSADAESKCVPANEIPDGWMGLDIGAESVDRFAALLTEAKTVFWNGPMGVFEFEKFAAGTRGVAEAIVAATGKGAFTVVGGGDSAAAVRALGLPEDGFSHISTGGGASLEYLEGKELPGISVLEDTAPEGS
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYB4_ORYSJ
Sequence: MGRAPCCEKMGLKKGPWTPEEDKVLVAHIQRHGHGNWRALPKQAGLLRCGKSCRLRWINYLRPDIKRGNFSKEEEDTIIHLHELLGNRWSAIAARLPGRTDNEIKNVWHTHLKKRLDAPAQGGHVAASGGKKHKKPKSAKKPAAAAAAPPASPERSASSSVTESSMASSVAEEHGNAGISSASASVCAKEESSFTSASEEFQIDDSFWSETLSMPLDGYDVSMEPGDAFVAPPSADDMDYWLGVFMESGEAQDLPQI
What is the function of this protein?
Transcriptional activator involved in cold stress response (PubMed:14675437, PubMed:20807373, PubMed:22246661).  Regulates positively the expression of genes involved in reactive oxygen species (ROS) scavenging such as peroxidase and superoxide dismutase during cold stress.  Transactivates a complex gene network that have major effects on stress tolerance and panicle development (PubMed:20807373).
What are the official names of this protein?
Transcription factor MYB4, Myb-related protein 4, OsMyb4, Transcription factor RLTR1.
What are the subcellular locations of this protein?
Nucleus.
Protein: EX7S_COXB2
Sequence: MPRKKTENFNFEASLNELTALVEKLEQGDLTLEESLQNFERGVGLVRSCQQALSDAEQKVKVLINQDGAETLVPFELETKTD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_MYCPA
Sequence: MPIIEQVGAREILDSRGNPTVEVEIALTDGTFARAAVPSGASTGEHEAVELRDGGERYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYLGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFAEALRWGAEVYHSLKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLIGRAIESAGFKLGTDVALALDAAATEFYSDGTGYKFEGSTRTAEQMAEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASIGDRVQLVGDDVFVTNPERLEEGIEKGVANALLVKVNQIGTLTETLDAVALAHHSGYRTMMSHRSGETEDTTIADLAVAVGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFALETR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: BTBDA_MOUSE
Sequence: MAGRPHPYDSNSSDPENWDRKLHSRPRKLYKHSSSASRVAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQHHIEREKDHSSSRPSSPRPQRASPNGSMSSAGNSSRNSSQSSSDGSCKTSGEMVFVYENAKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPSHPASGNNDLDPDAQNPML
What is the function of this protein?
Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated.  Plays a role in preventing motor neuronal death and in accelerating the growth of pancreatic beta cells.
What are the official names of this protein?
BTB/POZ domain-containing protein 10, Glucose metabolism-related protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with KCTD20 in filamentous structures.
Protein: MTFA_ECO81
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_COREF
Sequence: MTLRIFDTATRTLREFIPLKPGHASVYLCGATPQAQPHIGHVRSGVAFDILRRWLLAKGLDVAFVRNVTDIDDKILTKAAEHGRPWWEWVSTYEREFTWAYNTLGVLPPSVEPRATGHVTQMVQYMQRLIDNGFAYEVNGSVYFDVTAWVAAEGSDYGSLSGNRVEDMEQGETDNFGKRGPQDFALWKAAKPGEPSWPTPWGEGRPGWHLECSAMATYYLGAEFDIHCGGLDLQFPHHENEIAQAHAAGDGFARYWMHNHWVTMAGEKMSKSLGNVLSVPNMLEKVRPVELRYYLGSAHYRSVLEYSEGALTEAAAGYRRIEAFVDRVGEVEVGTWTAGFEAAMDEDLAVPKALAEIHNAVREGNSALAAGEMEKARELAGAVRAMTGVLGFDPVEWGTQTDDSAAHEALEVLVHAELERRATARAEKDWAVADEVRDRLAAAGIEVVDTADGVSWKLQ
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPO4_AGABI
Sequence: MSLLATVGPTGGVKNRLDIVDFVRDEKFFTLYVRALQAIQDKDQADYSSFFQLSGIHGLPFTPWAKPKDTPTVPYESGYCTHSQVLFPTWHRVYVSIYEQVLQEAAKGIAKKFTVHKKEWVQAAEDLRQPYWDTGFALVPPDEIIKLEQVKITNYDGTKITVRNPILRYSFHPIDPSFSGYPNFDTWRTTVRNPDADKKENIPALIAKLDLEADSTREKTYNMLKFNANWEAFSNHGEFDDTHANSLEAVHDDIHGFVGRGAIRGHMTHALFAAFDPIFWLHHSNVDRHLSLWQALYPGVWVTQGPEREGSMGFAPGTELNKDSALEPFYETEDKPWTSVPLTDTALLNYSYPDFDKVKGGTPDLVRDYINDHIDRRYGIKKSEGGKNPALDLLSDFKGVTHDHNEDLKMFDWTIQASWKKFELDDSFAIIFYFAADGSTNVTKENYIGSINIFRGTTPTNCANCRTQDNLVQEGFVHLDRFIARDLDTFDPQAVHRYLKEKKLSYKVVADDHSVTLKSLRIRVQGRPLHLPPGVSFPRLDKNIPIVNFDDVLDLVTGVVNIGLTAVGATAGVAIGVVGATAGTAIGVAGAATDAVTNIAKGGLGALGRIF
What is the function of this protein?
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, which associate in dark brown pigments.  Involved in the initial step of melanin synthesis.  Melanins constitute a mechanism of defense and resistance to stress such as UV radiations, free radicals, gamma rays, dehydratation and extreme temperatures, and contribute to the fungal cell-wall resistance against hydrolytic enzymes in avoiding cellular lysis.  Fungal pigments are also involved in the formation and stability of spores (By similarity).
What are the official names of this protein?
Polyphenol oxidase 4, PPO4, Phenolase 4, Cresolase, Tyrosinase 4.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
Protein: Y6038_DICDI
Sequence: MLVTYNGHVDDNSINNQIIENNVQTDDLNNSFDNHKDQIELKSYKETENIETENIETENKEVETINNEIIKISQEIEISKSQEIDKTNNNINEQNNDNFEIPEKELQEIEACPCNKNIIINDSNNYNVTIIQNDDSIVIENCTDCGDHITPKEEEEKEKEKEKEKEKEKEKEKEKEKDSEESLQEQCLNKENESIDNDNNNNIINNNNNDSIIIIKESTDDKKEIPSIECIQNNQNNQNNNDSPINKEIEDDNNNNIEKDGADIHIKEEQVEKVQVEEKEVEEIQVKDNANSVTSTIVTATDVTTTTTTTTTTTSSSNNCTNSISNTDKSTTTNCPPVENGGDSDGKLMYPLYKKVFGNKTISKLIFKNIRKIQRFKSITIESPSSPLPLSDIHGYGQVKSYSNITFEYMVFNWMIDLLHDKIVKNNEDLNFNNNNNNNNNNNNNNNNNSQPYHYQLKGSQSHEILLKNLKPNDENSKQLLKSFFKKYCDRNSILKKLTEYNNPLLTKLVLKDYLNDFKPVKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNSYFYKSVPNELLFNLILQQGEIKLVKQVLNGKYKELKLNQMSIHYALKSTLKNEIIQYIINNNRKELSQLYLKSNKCIVGSRRLFLSIFVPPPTTTTTTTNTNSTNTNSTINATSPPHTPKLSSSPLLTTTTTPPASPTQSRIPLVRTLTQLPSRIPLVRTQTQLQTKIQPKSPQPQPTAAPEPQKPPTPSIVKNQMHSQINITPQTKDYIEIGEMIGFEFRIFLELFEVTFPNVPKFRITESCVDSLKELVLKRSIENQNNKSIYSFDVLFDIFRITLHLVLIGCLKLIGDHENNNYNNNNNYNNNINNINYNNNINNNSYNNINNNNYNNNNKTTTTTTTTTTTTTANSNKSKTNKNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEKNIINNDNNINNNEIDISKDKKDLVKFRAIFNQINNLRQTYLFKKKNQEFEIEIKKLFFLDFIPLFGFNEKLLFEKSCLKIDLLHEEKKYGWIIGQEEQPNTLFIKEQLIKSSYEKLDANLFGLSVFLFGIERFSSGSQWFSYPNKIVNNKITNGPYNGNLDKQIQFLEGMIENCKTYKLFDRNETIGIIEAILNSIVITIQNNNDNNNNNNNNNNNNNNNNNNNNNNNNNYNIISIFEKKIQKLLGNCPIKVGAHSLFHSLELIEFCFNNCRDLINFSCCDSMNTLYRDSKFLSIIEFYHRNNLFFGNCSMEIGKSRKRSIAEKIYSFGYRFSNNLIPLAVYNDRESGYLFYYAVEKFIIEKLFNGDGSDYDESNCSSSSSSSESNGIDSGSESGRGRCRSNTTNNSNNINNSSNNNQRFQLHFLLSGNSIPRVIKRNEIFLPTNSKLKWFNLLLSSCGELFTYFPSNEGLCSDFDTPKTNFNLNYEEFYILKFITPFLYKKFKNSFSIKKDFYH
What are the official names of this protein?
Putative uncharacterized protein DDB_G0280555.