PharMolix/UniProtQA huggingface dataset:
Protein: XKS1_ASPNC
Sequence: MQGPLYIGFDLSTQQLKGLVVNSDLKVVYVSKFDFDADSHGFPIKKGVLTNEAEHEVFAPVALWLQALDGVLEGLRKQGMDFSQIKGISGAGQQHGSVYWGENAEKLLKELDASKTLEEQLDGAFSHPFSPNWQDSSTQKECDEFDAALGGQSELAFATGSKAHHRFTGPQIMRFQRKYPDVYKKTSRISLVSSFIASLFLGHIAPMDISDVCGMNLWNIKKGAYDEKLLQLCAGSSGVDDLKRKLGDVPEDGGIHLGPIDRYYVERYGFSPDCTIIPATGDNPATILALPLRASDAMVSLGTSTTFLMSTPSYKPDPATHFFNHPTTAGLYMFMLCYKNGGLARELVRDAVNEKLGEKPSTSWANFDKVTLETPPMGQKADSDPMKLGLFFPRPEIVPNLRSGQWRFDYNPKDGSLQPSNGGWDEPFDEARAIVESQMLSLRLRSRGLTQSPGEGIPAQPRRVYLVGGGSKNKAIAKVAGEILGGSEGVYKLEIGDNACALGAAYKAVWAMERAEGQTFEDLIGKRWHEEEFIEKIADGYQPGVFERYGQAAEGFEKMELEVLRQEGKH
What is the function of this protein?
Highly specific D-xylulose kinase which participates in the catabolism of xylose.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable D-xylulose kinase A, Xylulokinase A.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_MYCBT
Sequence: MPDPATYRPAPGSIPVEPGVYRFRDQHGRVIYVGKAKSLRSRLTSYFADVASLAPRTRQLVTTAAKVEWTVVGTEVEALQLEYTWIKEFDPRFNVRYRDDKSYPVLAVTLGEEFPRLMVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSAGVFKRHRQIDRPCLLGYIDKCSAPCIGRVDAAQHRQIVADFCDFLSGKTDRFARALEQQMNAAAEQLDFERAARLRDDLSALKRAMEKQAVVLGDGTDADVVAFADDELEAAVQVFHVRGGRVRGQRGWIVEKPGEPGDSGIQLVEQFLTQFYGDQAALDDAADESANPVPREVLVPCLPSNAEELASWLSGLRGSRVVLRVPRRGDKRALAETVHRNAEDALQQHKLKRASDFNARSAALQSIQDSLGLADAPLRIECVDVSHVQGTDVVGSLVVFEDGLPRKSDYRHFGIREAAGQGRSDDVACIAEVTRRRFLRHLRDQSDPDLLSPERKSRRFAYPPNLYVVDGGAPQVNAASAVIDELGVTDVAVIGLAKRLEEVWVPSEPDPIIMPRNSEGLYLLQRVRDEAHRFAITYHRSKRSTRMTASALDSVPGLGEHRRKALVTHFGSIARLKEATVDEITAVPGIGVATATAVHDALRPDSSGAAR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCIP1_MOUSE
Sequence: MGAVMGTFSSLQTKQRRPSKDIAWWYYQYQRDKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM
What is the function of this protein?
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels.  Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner.  Modulates KCND2/Kv4. 2 currents (PubMed:14572458).  In vitro, modulates KCND1/Kv4. 1 currents (By similarity).  Increases the presence of KCND2 at the cell surface.
What are the official names of this protein?
Kv channel-interacting protein 1, KChIP1, A-type potassium channel modulatory protein 1, Potassium channel-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm. Cell projection, dendrite.
Protein: DPO4_STAHJ
Sequence: MAERRIIHIDMDYFFAQVEMRDNPTLKGKPVIVGGKASTRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYYVRARFDAYREASAVIMSIFKSYTDIVEPMSLDEAYLDITHLVRPDLSASKIATFIRRDIFEQTGLTSSAGVSYNKFLAKLASGMNKPNGMKVIDYNNVNDILMNLDIGDFPGVGKASKKVMHNHDIYTGKDLYDKTEFELIRWFGKRGRGLYLKARGIDHSEVKATRVRKSVGTERTFSTDVNDDEEILQKIWELSGKTAERLSKLQKSGSTVTVKLKTYQYETFSKQRSLREAVSRDIDIYNVAYDLYNDLKDPDVPIRLIGVTVGNLEQSRYENMTIYDFIER
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTRC_METBF
Sequence: MSAGGAGGEAKGGYPPQTIMALGIVGGLVGIYLGNFAPPAYSFFGGLGAICATVWGADAVRRVASYGLGTGVPSIGMLALGMGILAALFGLSVGGTAGPIVAIVVAAIIGGVIGALANKVIGMGIPIMEKAMVEISCAGTLVILGLSVVIAGSFDFASVVQYVVANGYIALIFIIGGMGILHPFNASLGPDEKQDRTLMLAVEKGAIALIIAGFASSLHEGLMAAGLNMLIGIIIWYVAFSKHYALIKRDAYAVVGSGMLPSSEELQ
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit C, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C.
What is the protein family that this protein belongs to?
Belongs to the MtrC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYSI_XANOR
Sequence: MSHSVEDIKSESRRLRGSLEQSLADAVTGALREDDQTLIKYHGSYQQDDRDIRDERRQQKLEPAYQFMIRTRTPGGVITPAQWLALDGIATRYANHSLRITTRQAFQFHGVIKRELKATMQAINATLIDTLAACGDVNRNVQVAANPLLSQAHATLYADAACVSEHLLPNTRAYYEIWLDEERVSGSGNEDEPIYGDRYLPRKFKIGFAAPPLNDVDVFANDLGFIAILRDGRLLGYNVSIGGGMGASHGDAQTWPRVANVIGFVTRDQLLDIATAVVTTQRDFGNRAVRKRARFKYTIDDHGLDTIVAEIARRAGFALQPAQPFAFEHNGDRYGWVEGEDGLWHLTLSLPAGRIADTDTATHLSGLRAIAQLNVGEFRMTPNQNLVIAGVPASERARVDALVAQYALDAGNRSASALARGAMACVALPTCGLAMAEAERYLPDFSAALQPLLQQHGLADTPIVLRLSGCPNGCSRPYLAEIALVGKAPGRYNLMLGGDRRGQRLNTLYRENITEPEILAALEPLLARYAAERDHANDEGFGDFLHRAGLIALPSYPTHRRLDLELLA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate (Probable).
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: NDK_HALS3
Sequence: MTDHDERTFVMVKPDGVQRGLIGDIVTRLETKGLKMVGGKFMRIDEELAHEHYAEHEDKPFFDGLVSFITSGPVFAMVWEGADATRQVRQLMGATDAQDAAPGTIRGDYGNDLGHNLIHGSDHEDEGANEREIALFFDDDELVDWDRDASAWVYEDLADHD
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDJO_ECOLI
Sequence: MFSTNLIQSNYGDLNIKSLAFDSFKERLQSTMTALTFFISTGQCDCDEIAESNFNYMIAYMSNINYDASKPGAPALSFDTYLQDNVKYRVIINNLYGSEIRIRGINKDFIGMDVTSVFRPEKMTNLISIKNRLVIHYLRTIYYEQNYIHPVGSIFAAIQKNESLLKFPSIISMLNINLLFNPLNLPGMGSGVLEDIMSIPDSSLRKRLGYEVLSFSLQAHSLSQECIDKLDIFFADDLFKYESVCIAAMEHLKSKATAPIQNGPLPA
What are the official names of this protein?
Uncharacterized protein YdjO.
Protein: MDTI_SHIFL
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVVYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATG31_YEAST
Sequence: MNVTVTVYDKNVKYRLEENIKNNKGPSNDDQPAYNNESKSTDGSDYAMFPTNIKYIFEDNNDELVDSSDAALTAGIDKVGDELENVIIVQLDESGSLEDITLISDQYELLSHRTNSLSLEENQMRTLSSHGDDKSNDEEEELSVDSDRFRVDSDIELDVISQFCDLSPFLRDLSLNDLIKLYVTQNEQLQMLSNSV
What is the function of this protein?
Plays a role in starvation-induced autophagy.  Involved in mitophagy.  Functions with ATG17 and ATG29 at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions.  May be involved in microtubule function, such as chromosome segregation and karyogamy.
What are the official names of this protein?
Autophagy-related protein 31, CIK1 suppressor protein 1, Protein CIS1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Preautophagosomal structure.
Protein: GLGB_EMENI
Sequence: MTSTAPSDGTGIIDLDPWLEPFREAIKRRFDYVESWIKTVDEVEGGLDKFSKGYEKFGFNVSETGDITYREWAPNAIEAALVGDFNNWDTKANPMTRDNFGVWEIALPAKNGTPVIPHDSKVKITMVTRSGERIYRIPAWIKRVVQDLNVSPIYESVFWNPPKAERYNFQHARPKKPESLRIYEAHVGISSPDTRVATYKEFTANMLPRIKYLGYNAIQLMAIMEHAYYASFGYQVNNFFAASSRYGKPEDLKELVDTAHSMGLVVLLDVVHSHASKNVDDGLNMFDGSDHLYFHSGSKGQHELWDSRLFNYGNHEVLRFLLSNLRFWMEEYGFDGFRFDGVTSMLYTHHGIGTGFSGGYHEYFGPAVDDDGVMYLALANEMLHRLYPDCITVAEDVSGMPALCLPHGLGGVGFDYRLAMAIPDMYIKLLKEKSDNDWDIGNLAFTLTNRRHGEKTIAYAESHDQALVGDKSLMMWLCDKEMYTHMSVLTEFTPVIERGMALHKMIRLVTHALGGEGYLNFEGNEFGHPEWLDFPRAGNNNSFWYARRQLNLTEDHLLRYRFLNEFDRAMQLTESKYGWLHAPQAYISLKHEGDKVLVFERADLLWIFNFHPTESFTDYRVGVEQAGTYRVVLDTDDQAFGGLGRIDQGTRFFTTDMEWNGRRNYLQVYIPTRTALALALEETL
What are the official names of this protein?
1,4-alpha-glucan-branching enzyme, Glycogen-branching enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: PIMT_ECO7I
Sequence: MVSRRVQALLDQLRVQGIQDEQVLNALAAVPREKFVDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_STRPS
Sequence: MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEEMTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVNHIVVMGIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRNFADEGVQVNLAVSLHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNIKKLSYVNLIPYTPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGTDIDAAYGQLRSNTMKRDRQKAVAAVNP
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Putative dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSBW_STAEP
Sequence: MQSTQDYIEMRLPASAEYVSLIRLTLSGVFSRAGASYDDIEDSKIAVSEAVTNAVKHAYKKNSEIGMINLCFEIFDDRIKIVISDQGESFDYEATKSHLGPYNDNENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMIKYIKKEQVRNNGERVEIS
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: RS6_METEP
Sequence: MPLYEHVFLARQDVTAQQVETMVETYKGVIETGGGTIEKIESWGVKSLAYRIKKNRKAHFTLLNISAPPAAVAEMERQMQISEDVLRFMTVRVEQLEAEPSAMMQKRDRDDRKDRDRGDRPRRRDDDFGGGDRGDRGDRGDRPERNFGGEN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: EX7S_STAAN
Sequence: MTKETQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPP1_ARATH
Sequence: MTIGSFFSSLLFWRNSQDQEAQRGRMQEIDLSVHTIKSHGGRVASKHKHDWIILVILIAIEIGLNLISPFYRYVGKDMMTDLKYPFKDNTVPIWSVPVYAVLLPIIVFVCFYLKRTCVYDLHHSILGLLFAVLITGVITDSIKVATGRPRPNFYWRCFPDGKELYDALGGVVCHGKAAEVKEGHKSFPSGHTSWSFAGLTFLSLYLSGKIKAFNNEGHVAKLCLVIFPLLAACLVGISRVDDYWHHWQDVFAGALIGTLVAAFCYRQFYPNPYHEEGWGPYAYFKAAQERGVPVTSSQNGDALRAMSLQMDSTSLENMESGTSTAPR
What is the function of this protein?
Plays a general role in cellular responses to stress, may be by attenuating the signal produced by phospholipases.  Exhibits both diacylglycerol pyrophosphate (DGPP) phosphatase and phosphatidate (PA) phosphatase activities.  Substrate preference is diacylglycerol pyrophosphate > phosphatidate.
What are the official names of this protein?
Lipid phosphate phosphatase 1, AtLPP1, Phosphatidic acid phosphatase 1, AtPAP1, Prenyl diphosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: X_WHV3
Sequence: MAARLCCQLDSARDVLLLRPFGPQSSGPPFPRPAAGSAASSTSSPSPSDESDLPLGRLPACFASASGPCCLVFTCADLRTMDSTVNFVSWHAKRQLGMPSKDLWTPYIKDQLLTKWEEGSIDPRLSIFVLGGCRHKCMRLL
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: Y1357_HALVD
Sequence: MVTERSARESPEQRAAEQVVLVVDDDEDLADTCRYWLDGERFAVETAYGGEEALHRLDDTVDVVLLDRRMPNVTGDDVLEEIRERGLDCRVAMMTAVEPDTDIVEMPFDAYLVKPVSESEVKETVEELLVRSGFESGVREYFALESTEAALDSRDVEELREPEALSDLRSRLEAVRAEHEAAIRNREAQLDRLNRTNELLRDVDRALIDARTRDEIEQTVCDVVADAHEAAVVLRRTAAGTLRCTAAAGHGLDPAGVDLDFVDEAFGVDGAAEDGFVFEDIPGAHRAAVLGDDADDLDAVSALCVSIDYRETMYGALVVYDETDGFDDESAGLFSDLGATVGNGINATQSKRLLNGDSVVELEFQVGRDAGVLARLSAALDCQLSLDGVTRLDDGLACFISVAGASGCDAVAAAIDAVDVSQARVVADGDEESVVELRTDAEAVLSTAIDHGASVERLTLSEGSGTLTLHVAADADHGALVEAVTTAAAGVSVVAKREVERSVQSADSFRRALDSKLTDRQRTVLETSLVSGYFEWPRGSTAEEVADSLGISPPTLHEHLRTAERKLIETYFDELNQAPADD
What is the function of this protein?
May be part of a signal-dependent gene regulation cascade that is relevant to swimming motility.  May be involved in the transcription regulation of target genes.
What are the official names of this protein?
Putative transcriptional regulator HVO_1357, Bacterioopsin activator-like protein, Receiver/bat box HTH-10 family transcription regulator.
Protein: VATI_PYRAB
Sequence: MFKPEEIVKVEIITLARFRDTLLTYLHEMGVAQLDEVPIEGIQRDTPNEFYRKATSYSITLSRLIDTVKHYLPPRKGGIKEFIFPEEKKKRKYKYRGIEELIKDVEKFLGEAEPKIREVESEVSRLNNEISALKDSLNALELLSSLNIEIENLRGRSFLSVEVGLVDREKVENLIKELEEIAEGRVFTLRKDLAAKSLLVVVSLRKDSGKVISLLAKYGFEKIEIPEGEGLPKDLIPKYIERIKGKEKELEDVKLKGREIAEKYYEDLVFYKELMDNEREKSNFLSYLVRTEMTFGLLAWVPKKDVEKVVEGVKRITNGIAYIEVREPSEEEIENVPVKLKNPEFISHFEMLTEMYGVPKYNEIDPTPILAFTYSFFFGFMLTDFVYGLLLGVISALLVKGHSKLKDGTWKFAKIMLWASAFTMVLGILFGSYCGNLLDMAGVKVPRLLDTMSEALTVLVMALAIGLGHLFTGYILGFIVNWKNGDKRAAILEQLPWVFIIIGITLFALSSKLGIPQIAFKAVFGVGLALFVVGEIVNNKGMAVLLTISDFFGFIGNWLSYARLMALALATSGIALVINIIANMVWGLKIGPIPLGILIGIVILIGGHIFSTAINALGAFVHALRLHYVEFFGTFYSGEGRKFEPFAAKREVSELEIES
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit I, V-ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ALF1_PARBA
Sequence: MGVKDILSRKTGVIVGDDVLRLFQHAQEKVFAIPAINVTSSSTVVAALEAARDKNSPIILQVSQGGAAFFAGKGVPNGKQEASVAGAIAAAHYIRSIAPSYGIPVVLHTDHCAKKLLPWLDGMLDADECYFKLHNEPLFSSHMIDLSEESVEWNIETTAKYLKRAAPMKQWLEMEIGITGGEEDGVNNESVDNNSLYTQPEDIYTIYKTLSAISPYFSIAAGFGNVHGVYKPGNVRLHPELLSKHQAYVKEKTGSSKNKPVYLVFHGGSGSTKAEFKEAISYGVVKVNLDTDLQYAYLSGVRDFVLKKKDYLMSAVGNPEGEDKPNKKYFDPRVWIREGEKTMSARVQEAFDDFNTSNQL
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase 1, FBP aldolase 1, FBPA 1, Fructose-1,6-bisphosphate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: NTPPA_DICTD
Sequence: MRKEIILASNSPRRIYLLGQIGIDFKVVSPNVEEEGNSERRSPVDIVKSNALKKVQKVAEEYRNAIIIGADTVVVLDGEIIGKPKDERDAIRILKRLRDRYHFVFSGVAVMETPEEKVLTSVVRSKVKMRDYSDEEIERYVATGEPMDKAGAYGIQGKGALLVEKIEGDYYNIVGLPLVRLNSLLNRFGYSLL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIPS_PYRHO
Sequence: MLSKIRPKVKQPLERIGKTLASLGITPNQLTIIGFLITLLASYEFYLQNQILAGIILAVGAFLDALDGALARATGKVSKFGGFLDSTIDRLSDASILFGIALGGLVRWDVTFLTLIGSYMVSYSRCRAELAGSGTLAIGIAERGERIIIIFIASLFNAVKIGVYLVAILSWITFIQRVYEAKKRLEMG
What is the function of this protein?
Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate).  AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
What are the official names of this protein?
Archaetidylinositol phosphate synthase, AIP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBL4A_RAT
Sequence: MQLTVKALQGRECSLQVAEDELVSTLKHLVSDKLNVPVRQQRLLFKGKALADEKRLSDYNIGPNSKLNLVVKPLEKVLLEEGSAHRLVDSSATPIWQLISKVLARHFSIGDASRVLEQLQRDYDRSLSRLTLDDIERLASRFLHPEVTEAMEKGFCK
What is the function of this protein?
As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation.  The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane.  Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum.  Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome.  Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum.  The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome.  It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
What are the official names of this protein?
Ubiquitin-like protein 4A.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: ACCA_COXBN
Sequence: MNLDYLDFEQPIAELQAKIDELRRVGTSQEINLTEEVNKLEEKNAQLTRQIFSNLTAQQIVQLARHPLRPYTLDYIQRIFTDFNELHGDRHYSQASAIIGGLARLNGEPVMVIGHQKGRTTQEKIYRNFGMARPEGFRKALRLMKLAERFSIPVITLIDTPGAYPGIGAEERNQSEAIARNLFEMAQLKIPIICTIIGEGCSGGALAIGVGDRTLMLQYAYYSVISPEGCASILWKSAEKAGEAAEALGLTANRLHELGLIDEIIKEPLGGAHRDTDAMAEKLKKHLQANLTNLQAKSANDLLEERYRRWLSYGKD
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.