PharMolix/UniProtQA huggingface dataset:
Protein: PRMA_HELPH
Sequence: MLKPMYYEFFFIFPKERELFESFLLDTTHLALEESSLENLKAFDDKETIEFISQSSWHYFATHDPLKEHLKEKPQHLKNFVILRSQKDLNNSLILALEAFCLNLKQNLQSEFDFFYLSRNLASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHISTDDCIMIDPALAFGSGHHESTSMCLELLSDLDLKRKNALDVGCGSGILSIALKKQGVSALVACDTDSLAVEETLKNFSLNQIPLLAQDKVIYGSTQKIEGRFDIIVANLVADVVKSLYSEFVRLCNHTLILSGILETHLNSVLQIYYNGFEILEQRQRNEWVALKLLKKQPIN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIA2_RHIO9
Sequence: MSVYFDISIDGKPAGRIEFQLFEDVVPKTAKNFRALCTGEQGFGYKGSKFHRVIPQFMLQGGDFTRGDGTGGKSIYGEKFADENFKLKHSEPGLLSMANAGPNTNGSQFFITTVPCSWLDGAHVVFGKVTKNMELVSKIESLGSASGAVKAKVVIEDCGVL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A2, PPIase A2, Cyclophilin A2, Cyclosporin A-binding protein, Rotamase A2.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAS_YERPN
Sequence: MTVLHSIDFFSSSSAPVAIEARAPQSAFPEHHHDFYEIVIVEEGAGVHVFNGNPYTLSRGCVCFVRDHDRHLFESTDDLFLTNVLFRAPDAFRFLSGVGHFLPRECDGVYPSHWRVNGQVLQQIKCLIACLEHAPKSDQVEDIALHESVFMQLLVKLWQGCQTQVGDDQEGRLYQLLDWLQNNYSEAVEWPELADRFALPLRTLHRQLKNKTGMTPQRYLTRLHLLQARHQLCYSDNSVTDIAYLCGFGDSNHFSTLFKREFSQSPRDLRSQL
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_ACIBY
Sequence: MKAYTVEQGIVAPLDRANVDTDLIIPKQFLKSIKRTGFGDNLFDELRYLDEGYPGQDNSVRPKNPDFVLNQPRYQGATVLIARTNFGCGSSREHAPWALNEYGFRTVIAPSFADIFFNNCFKNGMLPVILPEDIVDQLFKECAAQEGYQLTIDLAAQEVRTPTGEAFKFEVDPFRKHCLLNGLDDIGLTLQNADAIRAYEEKTKQVRPWVFQEIN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CR1BC_BACTM
Sequence: MTSNRKNENEIINALSIPTVSNPSTQMNLSPDARIEDSLCVAEVNNIDPFVSASTVQTGINIAGRILGVLGVPFAGQLASFYSFLVGELWPSGRDPWEIFLEHVEQLIRQQVTENTRNTAIARLEGLGRGYRSYQQALETWLDNRNDARSRSIILERYVALELDITTAIPLFRIRNEEVPLLMVYAQAANLHLLLLRDASLFGSEWGMASSDVNQYYQEQIRYTEEYSNHCVQWYNTGLNNLRGTNAESWLRYNQFRRDLTLGVLDLVALFPSYDTRTYPINTSAQLTREIYTDPIGRTNAPSGFASTNWFNNNAPSFSAIEAAIFRPPHLLDFPEQLTIYSASSRWSSTQHMNYWVGHRLNFRPIGGTLNTSTQGLTNNTSINPVTLQFTSRDVYRTESNAGTNILFTTPVNGVPWARFNFINPQNIYERGATTYSQPYQGVGIQLFDSETELPPETTERPNYESYSHRLSHIGLIIGNTLRAPVYSWTHRSADRTNTIGPNRITQIPLVKALNLHSGVTVVGGPGFTGGDILRRTNTGTFGDIRLNINVPLSQRYRVRIRYASTTDLQFFTRINGTTVNIGNFSRTMNRGDNLEYRSFRTAGFSTPFNFLNAQSTFTLGAQSFSNQEVYIDRVEFVPAEVTFEAEYDLERAQKAVNALFTSTNPRRLKTDVTDYHIDQVSNMVACLSDEFCLDEKRELFEKVKYAKRLSDERNLLQDPNFTFISGQLSFASIDGQSNFPSINELSEHGWWGSANVTIQEGNDVFKENYVTLPGTFNECYPNYLYQKIGESELKAYTRYQLRGYIENSQDLEIYLIRYNAKHEAINVPGTESIWSISAESTIGKCTEPNRCAPHYEWNPDLDCSCRDGEKCAHHSHHSTLDIDVGCTDLHENLGVWLIFKIKTQDGHARLGNLEYLEEKPLLGEALRRVKRTEKKWRDKREKLHLETKRVYTEAKESVDALFVDSQYDRLQANSNIGMIHAADKLVHSIREAYLSELPVIRGVNADIFEELEGHILTAFSLYDARNAVKNGDFNNGLTCWNVKGHVDVQQSHHRFDLVVPEWKAEVSQAVRVCPGCGYILRVTAYKEGYGEGCVTIHEIEENTDELNFKNRVEEEIYPPDTGTCKYYTENQGTRTCGNECGSRNEGYDNAYEINAKSSLEYRPTYEEETYTDVRRENHCEYARGYINYSPVPAGYVTKELEYFPETDTVWIEIGETEGKFIVDSVELLLMEE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.
What are the official names of this protein?
Pesticidal crystal protein Cry1Bc, 140 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIB(c).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: A49_VACCC
Sequence: MDEAYYSGNLESVLGYVSDMHTELASISQLVIAKIETIDNDILNKDIVNFIMCRSNLDNPFISFLDTVYTIIDQENYQTELINSLDDNEIIDCIVNKFMSFYKDNLENIVDAIITLKYIMNNPDFKTTYAEVLGSRIADIDIKQVIRKNILQLSNDIRERYL
What are the official names of this protein?
Protein A49.
What is the protein family that this protein belongs to?
Belongs to the poxviridae A49 protein family.
Protein: TM143_BOVIN
Sequence: MLHVTRGVWGSIVRVWPLLPSFLGHSRALSSLEAKMGEYRKMWNPTEPRDWAQQYRERHIPFSKEQLLRLLIQEFHSTPAEKAALEEFTAHVDFCTLFHYHHVLTQLQALYDPINPDRETLDQPSLTDPQRLSNEKEVLQALEPLLAQANFSPLTEDTLAYALVVHHPQDEVQVTINLDQYIYMHFWALGQRVGKMPRKSSVGSKRFFFKSPPAERRYFKRVILAARTKKGHLVLKSFKDTPLEGLEQLLPELKVRTSTLQRAILNVTLIVSGVVFFVNVGMVVLSDLKMATSLLLLLFAAFMGLRAAKMFGHRRSAQALELAHMLYYRSTSNNAELLSALVLRAQDEHTKETLLAHSFLARRPGGAKGPPEETSQWLQSEVENWLLAQSGCDVAFNGKRALAHLQALPPTVGMYPPPGLPKLDLLATLSSPKSAPSDDNSLEKPLGPAQPSHLVGN
What are the official names of this protein?
Transmembrane protein 143.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BRWD3_MOUSE
Sequence: MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSAEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQTSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWIADAGINLQPPKRQTRQATQKIYSSSEDENLKLEDRQKKPKQTKKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPDGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCSDILDTYNKIKAEDPDSSDLEEDSEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKKQCEELLSLIYEREDSEPFRQPADPQSYPVQQQQEGESSQSVPPDRQDPSLSEDYQDGIDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENHIKNIISDYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVAYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSFSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEQVHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHTNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGSSRAKRARVADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY
What is the function of this protein?
Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape (By similarity).
What are the official names of this protein?
Bromodomain and WD repeat-containing protein 3.
Protein: VLF1_NPVOP
Sequence: MDGLGVRNETTFNDWKARIQSASRFEHVFDLATDRQRCTPDEVKNDSLWSKYMFPKPFAPTTLKSYKSRLIKIIFSLVEEADLQNPAYDLDREFDSVEFQHLLVSPKELCKRMLELRSVTKETLQLTINFYTNAMNLPEFKIPRMVMLPRDKELKTIREKEKNFMLKNAIDTILNFIDSKIKLMNSDYVHDRGLIRGAIVFCIMLGTGMRINEARQLSVDDLNVLIKKGKLRSDTIGLKRKRSRKNTLNNIKTKPLELAREIYARNPTVLQISKNTSTPFKDFRRLLDEAGVEMERPRSNMIRHYLSSNLYNSGVPLQKVARLMNHESPASTKPYLNKYNFDESSSDEESGGNNRDSSTGSSANSSSLYYQTGD
What is the function of this protein?
Involved in very late gene activation.
What are the official names of this protein?
Very late expression factor 1.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: ATPZ_BACSU
Sequence: MDDPKLTFSRQRKYLLFILAVYVLGYGLTAYKTVFLGLILGTVFSLFNFLLLVRRMNAFDRAVEKGKSIRSLGSAARWCNAILAVAVAYKNPEYFHMASTVIGLMTIYPVIMIDSFIQLKRSSMEER
What is the function of this protein?
A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
What are the official names of this protein?
ATP synthase protein I.
What is the protein family that this protein belongs to?
Belongs to the bacterial AtpI family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL43A_SCHPO
Sequence: MTKRTKKVGVTGKYGVRYGASLRRDVRKIEVQQHSRYQCPFCGRNTVKRTAAGIWCCNGKGCKKVLAGGAWTVTTAAATSARSTIRRLREMVEV
What are the official names of this protein?
60S ribosomal protein L43-A, L37A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: CDPK9_ORYSJ
Sequence: MGNTCCVAPATTDEVGAPPRDHHHAAKKSPAPSATTTTATRQRHGQEPKPKPKPRARAKPNPYDWAPPRVLPARGGAAASAVRVLEGVVPHHPRLRVTDKYQLGRELGRGEFGVTHLATDRATRERLACKSIPKRRLRTAVDVADVRREVAIMASLPDHPALVRLRAAYEDADAVHLVMELCDGGELFDRIVARGRYTERAAAAAARTVAEVVRACHAHGVMHRDLKPENFLYAGKAEDAQLKAIDFGLSVFFRPGERFREIVGSPYYMAPEVLRRDYGPEVDIWSAGVILYILLCGVPPFWAETEQGVARAILRGAADFDREPWPRISRAAKSLVRQMLDVDPRRRPTAQQVLDHPWLHHAARAPNVPLGDVVRARLKQFSLMNRLKKKAMRVIAEHLSVEEVEVIKDMFALMDTDNNGRVTLQELKDGLTKVGSKLAEPEMELLMEAADVDGNGYLDYGEFVAVTIHLQRLSNDNHLRTAFLFFDKDGSGYIDRAELADALADDSGHADDAVLDHILREVDTDKDGRISYEEFVAMMKSGTDWRKASRQYSRERFKTLSNSLIKDGSITMAR
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity).  Functions in signal transduction pathways that positively regulate responses to drought, osmotic, and dehydration stress.  Regulates expression of stress-associated genes in response to drought.  Involved in tolerance to drought stress by increasing proline and soluble sugars, and improving stomatal closure.  Required for pollen maturation and spikelet fertility (PubMed:24884869).
What are the official names of this protein?
Calcium-dependent protein kinase 9, OsCDPK9, OsCPK9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: CSTP1_MOUSE
Sequence: MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTDYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGDAGMLDGVEASLFYQRLENLCDRHKYSCPPPALVKEILSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLLVQVPGLVNSITATSEASCLPSRTPPRVGSPWKPLHRSRKLDAESDGSTEETDESET
What is the function of this protein?
Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly.  Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding.
What are the official names of this protein?
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1.
What is the protein family that this protein belongs to?
Belongs to the CSTPP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Protein: TDH_PHOPR
Sequence: MKIKALSKLKPEEGIWMNEVDKPEMGHNDLLIRIKKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVRGFTIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRDGAFAEFLVIPAFNAFKIPAGISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVITDVNEYRLDLARKMGVTRAVNVANEKLEDVMSELGMTEGFDVGLEMSGVPSAFNGMLASMNHGGKVALLGIPPSDMAVDWTQVIFKGLVIKGIYGREMFETWYKMASLIQSGLDLTPIITHHYKIDDFQKGFDMMRSGMSGKVILDWE
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_FRATT
Sequence: MSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTTKTVFNQETTYHNLLKLKKWQANGVIGIIYDNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSVLLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNLLSKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ACTP_ECOL6
Sequence: MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMHFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWLFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADA2_SCHPO
Sequence: MPPQKYHCNVCAQDITRSIHIRCVECVDFDLCIPCFTSGASLGTHHPSHPYRIIETNSYPIFDENWGADEELLLIDACETLGLGNWADIADYVGNARTKEECRDHYLKTYIESDCYPLASVELPGPVDRIAFAARKRARIEAFQPPPIIPQKPLASTPQCHEIQGYMPGRLEFDQEYMNEAELPIKDMNFDDDLHESAKHEMQLKLTMLNIYNSRLTRRAVRKQTIFNHNLLDYRRLQANEKRMSKEERNLLNKTKAFARLLTGPDYQKFVNSYHEQITLKKQISDLQEWRQMGLTTLEQGHKYERDKTQKFLLSKASASYDKQLRHVKSFNQTTSAPFQVRDIQKIVPRKPATPTMFSASADRQLLSEDEQALCSKLQIFPKPFLALKFALISASLTSKKPFQKTDAVNLFKHLDANKVEQVYDFFHNARWIGAPT
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA.  SAGA is involved in RNA polymerase II-dependent transcriptional regulation.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation (gcn5) and deubiquitination (ubp8).  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation.  SLIK is proposed to have partly overlapping functions with SAGA.  It preferentially acetylates methylated histone H3.  ADA preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B (By similarity).  Required for full activation of chromatin alteration and meiotic recombination at meiotic recombination hot spot ade6-M26.  Also required for the regulation of transcription and chromatin structure around ade6-M26 in response to osmotic stress.  Needed for hyperacetylation of histone H3 around ade6-M26.
What are the official names of this protein?
Transcriptional adapter 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENTP1_BOVIN
Sequence: MEDRRESELKVFCSKNILSILGFSCIIAVIALLALGLTQNKALPENVKFGIVLDAGSSHTSLYIYRWPAEKENDTGVVTQIEESNVKGPGISGFAKKVNEINVYLTACMERAQKVIPSIQHMETPVYLGATAGMRLLRMENKQMADKILAAVASSISEYPFDFQGARIISGQEEGAYGWITVNYLLGKFTQKLSWFNLKPSKDDTQETYGALDLGGASTQITFVPQNETTESPNNNLYFRLYGKNYSVYTHSFLCYGKDQALLQKLALGLQGTNGIIHEPCFHSRYMRKIKMSVLNEGFCTKRHELNSSFYPLVDIEIRGAGNFQRCRQSIIQLFNTSYCPYSSCSFNGVFLPPLHGQFGAFSAFYYVMEFLNLTSEESVSVEQLTEKLEEFCAQRWEEVQKNFGEVKEKYLSEYCFSGTYILVLLLNGYHFTAESWKNIHFMNKVRSTDVGWTLGYMLNLTNKIPAEEPMSPPLPHSTYVFLMVLFSLILLAVIIVGIVVFHKPSYFWKDMV
What is the function of this protein?
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.  Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.  Hydrolyzes ATP and ADP equally well.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 1, NTPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPDase 1, Ecto-ATPase 1, Ecto-apyrase, Lymphoid cell activation antigen.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MINE_PSEF5
Sequence: MNLFDFFRASKKVSTASVAKERLQIIVAHERGQRSTPDYLPALQKELVEVIRKYVNIGSDDVHVALENQGSCSILELNITLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: UREG_METS5
Sequence: MIKVGILGPVGSGKTSLIEFLAKEYSERGIKVGILTNDVVSAYDAMRIYHNLVERLRILPRENVLGLVTGGCPHTAIREDPSLNLRALETLEERANPDLVFIESGGDNVMSTFSSSLADFTIFVLDTSAGDKYPGKGGIGITESDLLVVNKIDLAPYVQADLNKMREDSLRVRRGKPSVFISLKTGEGTRELIRILDEELGLERVFGNKGQ
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FH2_ARATH
Sequence: MTTIPFCFLFVAFFFSSSTADQRHHSRHLLHQPFFPVVTAAPPPYQPPVSSQPPSPSPHTHHHHKKHLTTTTPPPHEKHLFSSVANPPPPPPSPPHPNPFFPSSDPTSTASHPPPAPPPPASLPTFPANISSLLFPTHNKQSKPPSNGHIARLVTITASVISAAALLSLFAVFIIFIRRTRHRRRSSPADDTKSTRSDALQLFNASPSDGSKKQKQHQQPPKYTSSHTSSEFLYLGTLVNSRSNGLEQQKSPISLSGGITGVLELPPPASSSSSSSYSQYHKLGSPELRPLPPLPKLQSFTPVYKSTEQLNPKRQDFDGDDNENDEFFSPRGSSGRKQSPTRVSDVDQIDNRSINGSGSNSCSPTNFAPSLNASPGTSLKPKSISPPVSLHSQISSNNGIPKRLCPARPPPPPPPPPQVSEVPATMSHSLPGDDSDPEKKVETMKPKLKTLHWDKVRASSSRVMVWDQIKSNSFQVNEEMIETLFKVNDPTSRTRDGVVQSVSQENRFLDPRKSHNIAILLRALNVTADEVCEALIEGNSDTLGPELLECLLKMAPTKEEEDKLKELKDDDDGSPSKIGPAEKFLKALLNIPFAFKRIDAMLYIVKFESEIEYLNRSFDTLEAATGELKNTRMFLKLLEAVLKTGNRMNIGTNRGDAHAFKLDTLLKLVDIKGADGKTTLLHFVVQEIIKFEGARVPFTPSQSHIGDNMAEQSAFQDDLELKKLGLQVVSGLSSQLINVKKAAAMDSNSLINETAEIARGIAKVKEVITELKQETGVERFLESMNSFLNKGEKEITELQSHGDNVMKMVKEVTEYFHGNSETHPFRIFAVVRDFLTILDQVCKEVGRVNERTVYGSMPLHSPSNQTATPLFPVVINNNSRLSPSGSLDDDDGSF
What is the function of this protein?
Might be involved in the organization and polarity of the actin cytoskeleton.
What are the official names of this protein?
Formin-like protein 2, AtFH2, AtFORMIN-2.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MTCH1_HUMAN
Sequence: MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGSGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE
What is the function of this protein?
Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (PubMed:36264797).  Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins (By similarity).  Does not mediate insertion of beta-barrel transmembrane proteins (By similarity).  May play a role in apoptosis (PubMed:12377771).
What are the official names of this protein?
Mitochondrial carrier homolog 1, Presenilin-associated protein.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: MED22_CANAL
Sequence: MQPKSISLLQKIDSIIETIIVKFTNIFENLQDANKTTEILSMESLAMENNCIQIIRLCQDLISISRNLKEIWVLNSIKVTQEKFEWKQEEIDIMFTQFNLLTDKIAEFETDMNKE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 22, Mediator complex subunit 22.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_TROWT
Sequence: MTCYTPRLLTRYREEIVPVLMSRFDINNVHQVPSITKIVVNSGVGDAARDSKIIEGAVSDITLITGQKPRINRAKQSIAKFKLREGQAVGVTATLRGRRMWEFLDRLLTLALPRIRDFRGISDKQFDGHGNYTFGLSEQGIFHEIDQDKIDRVRGMDITVVTTSSSDDMARALLGELGFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TAU_SPECI
Sequence: MAEPRQEFDTAEDHAEGYALLQDQEGEHGLKASPLQTPADDGPEEPVSETSDAKSTPTAEDVTAPLVDERTPGEQAATQPPTDIPEGTTAEEAGIGDTPNMEDQAAGHVTQARMVSKGKEGTGSEDRKAKGADSKTGTKIATPRGTAPPGQKGTANATRIPAKTTPSPKTPPGTGEPAKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSTKSRLQTAPVPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSINMVDSPQLATLADEVSASLAKQGL
What is the function of this protein?
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity.  The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.  Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.  The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
What are the official names of this protein?
Microtubule-associated protein tau.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.