PharMolix/UniProtQA huggingface dataset:
Protein: ATPG_XANCP
Sequence: MAGGREIKTKIKSVQNTRKVTRALEMVSASKIRKAQERMKTSRPYAQAMKQVIGHLAQASTDYQHPFLVEREQVKRVGYIVISSDRGLAGGLNNNLFRKMLGEVRPWQDKGAEIDVVTIGQKASAFFRRIKVNMVGSVTHLGDSPHIEQLVGVIKVMLDAFTEGKVDRVYLVYNRFVNTMTQKASFEQLLPLPAAEHKVAHHDWDYLYEPDAATVLEHVMTRYIESLVYQAVLENVASEHAARMVAMKAASDNANKMIGTLQLVYNKARQAAITQEISEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PP4R3_XENTR
Sequence: MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDPIDESEEERFEEMPETSNLIDLPTCELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQTCENLDNTEGLHHLYEIIRGILFLNKAALFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDVILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLANLGILPALEIVMGMDDLQVRAAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDSDPELGGAVQLMGLLRTLIDPENMLATANKTEKSEFLNFFYNHCMHVLTAPLLANTSEDKLEKDAVLGSIKTSTVCPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLILMNSKHTFLALCALRFMRRIIGLKDEFYNRYIIKGNLFEPVINALLDNGTRYNLLNSAIIELFEFIRVEDIKSLTSHIVENFYKALESIEYVQTFKGLKTRYEQEKDRQSQKLSSVPSILRSNRFRRDARALEDDEELWFNEDEEEEGEAVVPPVEKTKTEDDFPEGYEKFLETKKAKELEDKENLPKRTSVGGFKFTFSHSVSAANGANSTNSKSVAAHTPPASSNGSSSKNTSLTTTVASAKGSLIGLVDYPDDEDEEEEEDTSPRKRPRLGS
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 3, SMEK homolog 2.
What is the protein family that this protein belongs to?
Belongs to the SMEK family.
Protein: TRM13_DICDI
Sequence: MGEINNNKEINEKDDEINNKRLKYEGFIKKEKKKKQKIDHSIPLKEKPTQEDIDSHSECLFWIVNKKKHRAEFCKYKRAKDSILCNHHKPIDQISSEPQPQLTDYNGDDVTENNNNSTTTTTATTQDDNSKPKERKRIHCPLNPTHIIYECKLQKHLKACPNAKVGQKNAHIELSKKEPYYKENINDLNENVKLTLEPIILSQVSTENLINISIKLDQFFEKFFKNEIQSLNQTHKSFDKIFNSDQQLKHIQQESSIINLLENSNLYNSDNVYLEFGAGSGKLSNHIFMSHEKKSGHILIDRMKFRSLKKVDRLIKNEKGCHHFSRLLIDIRHLNLSNLSILEEKPFVITSKHLCGCATDFTLDSIFNLLNNSNEKVNNNFKGIGIATCCHHICNFNTYSNQSYLKDQLNITPLEFQLICSISSWATIDENKCNNDDDDNEVEEDDELIKKDKKEKKEFENQLKIEFNKQDVFSIKRKEELGYKAKRLIDYGRYLFIKEKLNLPNTKFWIYTNQSKENLFLVSNK
What is the function of this protein?
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
What are the official names of this protein?
tRNA:m(4)X modification enzyme TRM13 homolog.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase TRM13 family.
Protein: MTNN_ALKCK
Sequence: MKIGIIGAMEEEVNFLRDKMENRVATTIANCEFTEGQIGAVQVVLTRCGIGKVNAALATTLLNDRFQPDAIINTGVAGGLNASMAVGDLVISTEVRYHDVDATVFGYEYGQVPGMVPAYLPDATLIAAAKTAAQKVGFHSEEGLIVTGDSFMGEETRVNEVKTLFPAAYCAEMEAGAIAQVCHQFQTPFVIIRALSDVAGQDAKMSYDTFLEKSAVNSAKQVMLMLDHLSA
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: ZN746_MOUSE
Sequence: MAEAAAAPISPWTMAATIQAMERKIESQAARLLSLEGRTGMAEKKLADCEKTAVEFSNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGEVPKEWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPEVLSQIEQGKEPCTWRRTGPKVPEVPVDPSPGSGAPVPAPDLLMQIKQEGELQLQEQQALGVEAWAAGQPDIGEEPWGLSQLDSGAGDISTDATSGVHSNFSTTIPPTSWQADLPPHHPSSACSDGTLKLNTAASTEADVKIVIKTEVQEEEVVATPVHPTDLEAHGTLFAPGQATRFFPSPVQEGAWESQGSSFPSQDPVLGLREPTRPERDIGELSPAIAQEEAPAGDWLFGGVRWGWNFRCKPPVGLNPRTVPEGLPFSSPDNGEAILDPSQAPRPFNDPCKYPGRTKGFGHKPGLKKHPAAPPGGRPFTCATCGKSFQLQVSLSAHQRSCGLSDGAATGAASTTTGGGGGGSGGGGGSSGGGSSARDSSALRCGECGRCFTRPAHLIRHRMLHTGERPFPCTECEKRFTERSKLIDHYRTHTGVRPFTCTVCGKSFIRKDHLRKHQRNHPAVAKAPAHGQPLPPLPAPPDPFKSPAAKGPMASTDLVTDWTCGLSVLGPSDGGGDL
What is the function of this protein?
Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death.
What are the official names of this protein?
Zinc finger protein 746.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly localizes to the cytoplasm; probably translocates to the nucleus to repress selected genes.
Protein: RR18_OSTTA
Sequence: MNFTRQRTSPIHAGEIISYKNVDLLRRFITEQGKILPRRLTGVTAKEQRQLAKAIKQARILGFLQFLYKE
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNC_MYCLE
Sequence: MTQPRQALLDAFGVDLPDELLSLALTHRSYAYEHGGLPTNERLEFLGDAVLSLTITDELFHRHPDRSEGDLAKLRASVVNTQALAYVARNLSDGGLGVYLLLGRGETNTGGADKSSILADGMESLLGAIYLHHGIEVARQVILRLFGTLLDAAPTLGAGLDWKTSLQELTAARGMGVPSYVVTSTGPDHDKEFTAVVVVMDTEYGSGIGHSKKEAEQKAASAAWKALDVLGGVGKTSV
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF3_CHAVU
Sequence: MPRSQKNDNFIDKTFTIIADILLRIVPTSQREREAFTYYRDGMSAQAEGEYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHAKALEYYFQALERNPSLPQAFNNVAVICHYRGEQAIQQQDIESSKAWFNQAAEYWKQAIQLAPGNYIEAQNWLKITGRI
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TRIM8_HUMAN
Sequence: MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQSVPLYPCGVSSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASGEGQSGQPLGPCSSTQHLVALPGGAQPVHSSPVFPPSQYPNGSAAQQPMLPQYGGRKILVCSVDNCYCSSVANHGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLPSLAVRDWLDASQQPGHQDFYRVYGQPSTKHYVTS
What is the function of this protein?
E3 ubiquitin-protein ligase that participates in multiple biological processes including cell survival, differentiation, apoptosis, and in particular, the innate immune response (PubMed:27981609, PubMed:28747347).  Participates in the activation of interferon-gamma signaling by promoting proteasomal degradation of the repressor SOCS1 (PubMed:12163497).  Plays a positive role in the TNFalpha and IL-1beta signaling pathways.  Mechanistically, induces the 'Lys-63'-linked polyubiquitination of MAP3K7/TAK1 component leading to the activation of NF-kappa-B (PubMed:22084099, PubMed:23152791, PubMed:27981609, PubMed:34871740).  Modulates also STAT3 activity through negative regulation of PIAS3, either by degradation of PIAS3 through the ubiquitin-proteasome pathway or exclusion of PIAS3 from the nucleus (PubMed:20516148).  Negatively regulates TLR3/4-mediated innate immune response by catalyzing 'Lys-6'- and 'Lys-33'-linked polyubiquitination of TICAM1 and thereby disrupting the TICAM1-TBK1 interaction (PubMed:28747347).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM8, Glioblastoma-expressed RING finger protein, RING finger protein 27, RING-type E3 ubiquitin transferase TRIM8, Tripartite motif-containing protein 8.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nuclear body. Note=Nucleo-cytoplasmic translocation is involved in regulation of NF-kappa-B.
Protein: NPIIB_TRIVH
Sequence: MQVIVALAALGSLAAPALGFSIPRGVPVSQSMIDVKLSSTGNSMVKATITNNGNRALNLLKFHTIMDSNPTRKVSIESEDGKEIQFTGMMPTYKEKDLKPSYFIFLPPKGTVEHSFDIARTHDLSRGGKFTLKAEGMVPIAEENGTEITGAAKYHSNELHMTIDGEKAASVENAFGIVKRGPLTRINKRTSIDMQSCGNNQELQALTAALKASAQLSSMSAQAVSQNQDKYMEYFKDPQYMQTVQSRFQAVAQESSSTTGGGTTYHCSDTMGGCEEGVLAYTLPSQNEVFNCPIYYSDLPPLSNECHAQDQATTTLHELTHNPAVQEPFCEDNGYGYERATALSAEKAVQNADSYALFANGKLNLITLMLIDPD
What is the function of this protein?
Probable secreted metalloprotease that shows high activities on basic nuclear substrates such as histone and protamine (By similarity).  May be involved in virulence.
What are the official names of this protein?
Probable neutral protease 2 homolog TRV_05367, Deuterolysin TRV_05367.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DERF6_DERFA
Sequence: MIKIFLVTILIVITVTVDARFPRSLQPKWAYLDSNEFPRSKIGDSPIAGVVGGQDADLAEAPFQISLLKDYLIMKRHMCGGSLISESTVVTAAHCTYGQKASSLSVRYGTNQRTSSSYGDLKVKPIIQHESYEQDQTQTDKTIIILPNPVVPSTNVQMNEIETEDIVDGDKVTIYGWGLTDGNGKDLPDKLQKGSMTIVGNDRCNEKWGSINAIHPGMICALDKTQSGCNGDSGGPLVSANRKLTGIVSWGPSKCPPGEYMSVFTRPKYYLDWITKNIV
What is the function of this protein?
Protease that shows specificity similar to chymotrypsin.
What are the official names of this protein?
Mite allergen Der f 6, Allergen Der f VI, DF5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RABA3_ARATH
Sequence: MNEEMSGESPENNKHVKKPTMPEKIDYVFKVVVIGDSAVGKTQLLSRFTHNEFCYDSKSTIGVEFQTRTITLRGKLVKAQIWDTAGQERYRAVTSAYYRGALGAMVVYDITKRLSFDHVARWVEELRAHADDSAVIMLVGNKADLSVGKRAVPTEDAVEFAETQRLFFSEVSALSGGNVDEAFFRLLEEIFSRVVVSRKAMESDGGATVKLDGSRIDVISGSDLETSNIKEQASCSC
What is the function of this protein?
Intracellular vesicle trafficking and protein transport.
What are the official names of this protein?
Ras-related protein RABA3, AtRABA3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endosome membrane. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Note=During cytokinesis located to the growing margins of the cell plate.
Protein: RF1_HALH5
Sequence: MFERLQSLDERYERLNELLSDPEVISDSNKLREYSKEQADMEETVQVYREYKTVMDQYQDAKEMLEDKLDDEMYAMVKEEIDELATRKEDLEAKLKVLLLPKDPNDDKNVIVEVRGAAGGDEAQLFAADLYKMYARYAEAQGWKIEVIEASSTELGGYKEIIFSVNGKGAYSKLKYENGAHRVQRVPQTESGGRIHTSTATVAVLPEAEEVEVDIHEKDIRVDTFASSGPGGQSVNTTMSAVRLTHLPTGIVVSCQDEKSQIKNKEKAMKVLRARIYDKFQQEAQAEYDQTRKSAVGTGDRSERIRTYNFPQSRVTDHRIGLTLQKLEQILQGKLDEIIESLIVHEQAELMKQQED
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
Protein: NU1M_TADIN
Sequence: MFLMNLLSMIIPILLAVAFLTLVERKILGYMQLRKGPNIVGPHGLLQPIADAIKLFTKEPLQPLTSSTTMFIMAPILALTLALTMWIPLPMPYPLINMNLGILFMLAMSSLAVYAILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMNGSFTLSTLIVTQEYTWLIFPSWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANIIMMNILTTTLFLGAYHSPTMPELYTTNFVTKTLLLTTTFLWVRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVSMPITMASIPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL9_NEOSM
Sequence: MLVILKETARKLGNVGDVLKVKKGFARNYLIPSGKAVRATRANLAILENSKEKLAAQQAAELETASELAKSFTEIDVLPIYAQAERGVLFGAVSAKQVVAELSKKGIEITTKNVVLGAPIKALGEHEVRIFLHSRVECSLKIHILDASRRGADGTITGTS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DTD_PSE14
Sequence: MKGLLQRVRNARVEVGGEVVGAIDQGILVLVGIEPQDTRASADKLLHKLLNYRVFSDADGKMNLSLREVGGGLLLVSQFTLAADTKSGLRAGFSKAAAPALGAELFDYLLSQARIAHTAVAAGQFGADMQVHLINDGPVTFLFDT
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_CELJU
Sequence: MREKIRLNSSAGTGHFYTTDKNKRTMPEKMEIKKYDPVVRKHVVYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MNMC_CAMJ8
Sequence: MKKAKLIFKDNTPFSLDFDDFYFNSKDGLNESKFVYTHSFEWKNQENFIIAESGFGIGLNFFLTLKRFLQTTPSKRPKKLFYISIEAFYIEKEQLREIYQKLGFYEEFKELLEQFLKFYPKAKEGIYRFYFEDCFLDLVFEDITILKELDFKADIWYLDGFSPNKNSQMFDENLIFEVARLSKKNTQICTFSSASFLQKNLKKYGFRVEKTKGFRKREMIKAYLENELEFKDKEAYFSRTFSSLKNKKVAIIGAGISSAVLAYELSLRGFEIDVFEKHLELGKGASGNESGILSSLILKPKVNLGEFSELSFIEASRFYRQILDLEFKGVVEFAHNDLMQERFDTQRENVLFKISKNQAFLEEGGVIFPKNLVKNLFEKSKACIYFNHEFQAYKFENECFTLKFKNDIVKSDYAVLIYAMGADTKDFVFYDEMKLSKVRGQVTHLKPFLNTPFPLSSKAYICPVKDDLQVIGASYDRLDASLESKEEDDKQNIENIAEFIDKNTKLEIIGSKVGFRSYSSDRFMIVGNAYDEVFYKEEYKALLWTKNKEQKLAKISCNLYFNFAHGSRGFSTSVLAARYLCALINNEPLYLEKKYIHAIHPARFLIRKLKKGL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_ALISL
Sequence: MAKQPTRARKRVRKQVADGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCGEMAKEYGVKNLEVMVKGPGPGRESTIRALNAAGYRITNIVDATPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: EFG_RHILO
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTTTERVLYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWKGRDGKMRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQADKYRVPRMIFCNKMDKIGADFYRSVEMIGSRLGAQAVVMQLPIGAETEFKGVVDLVEMNALVWRDETLGAAWDVVEIPADLQARAQEYREKMIEAAVEMDETALENYLEGKMPSNDEIRSLIRKGTIAVKFFPMFCGSAFKNKGVQPLLDAVVEYLPSPADVPAIKGVDAKTDAEIERHAVDDEPLSMLAFKIMNDPFVGSLTFARIYSGKLTKGISVDNTVKGKKERIGRMLQMHANSRADVEEAFAGDIVALAGLKDTTTGDTLCDPLHPVILERMEFPDPVIQIAIEPKTKNDQEKMGLALHRLAAEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFKVEANVGAPQVAYRETITRKHEQDYTHKKQTGGTGQFARVKVLFEPNTESEEFVFESKIVGGAVPKEYIPGVEKGIQSVMGAGPFAGFPMIGVRATLIDGAYHDVDSSVLAFEIASRACFREAAPKLGVQLLEPIMKVEVVTPEDYVGSVIGDLNGRRGQIQGQEARGVAVVINAMVPLANMFKYVDNLRSMSQGRAAYTMQFDHYEPVPTAVAQEVQKKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_EUCGG
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CTAA_NOVAD
Sequence: MSASPSPSTRADALALARWLFVVAFMVVAIVAVGGITRLTESGVSITEWKPVAGTLPPITDAQWQAEFDAYRQTPQFQLVNGPAGMTLATYKFIFFWEWVHRLLARTIGLVFAAPLAWFWIKRRIPEGYKPRLVALLALGALQGAVGWWMVKSGIVNDVKVSHFRLATHLLVALFTLGGLVWTALDLVALSKGEARSRLRGIGLLALAMLVLQLFYGALVAGLRAGTSAGGGWFNWDAWPLMQGSLYPDGVDWATGAVHALLSDVFLVHFIHRWWAWAVVAVLVVVARKLRKTNRKASIVLHSVFGTQVLLGIFTVWSGVALWIAVLHQFVGALLVAATTWSAHLLGARR
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AQP2_GIBZE
Sequence: MPISTINDSISESSVHKSSIPTKVEMSQNEKYSEAPSEAPTIPPPPEQYAWSRIRENCQDAFSEFFGTFVLLLFGDGVVAQVVLSRGTKGDYQSISWGWGLGVMLGVYVGGKSGGHLNPAVTLANCLFRGHPWRKFPIYAVAQVLGAMAAAAVVYGNYKSAIDAYEGGPGIRTVIGENATAGVFCTYPAEFMTRTGMFFSEFIASTILQFVIFAMADSANIGAGPLMPLGLFFLIFGIGACFGWETGYAINLARDFGPRLVSYMLGYGSEVWSAGGYYFWIPMVAPFFGCAFGGFLYDVFIYTGPSPINTPGMGFGRLVSPRRSTWSNTYNANSPV
What is the function of this protein?
Probable water/glycerol channel that may have redundant functions with FgAQP4.
What are the official names of this protein?
Probable aquaglyceroporin-2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: CALYP_DROPS
Sequence: MNVAAGGPGTASASTTAANSIFNNSLLASATGATTMPMAQLADGWLELESDPGLFTLLLEDFGCHDVQVEEVYDLQKPIESPYGFIFLFRWIEERRARRKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLSRLKVHTKGMSPENKGLAIGNTPELACAHNSHAIPQARRRLERTGAGVASCRFTGEAFHFVSFVPISGQLFELDGLKPYPMNHGGWEDHEDWTDKFRRVMAERLGIATGEQDIRFNLMAVVPDRRIAITHKLKMLRTNQAIVSGTLQKLLKADEQGESGNGDQQRPDTPTTLLEPSAFTAKDLQLLLKNLDTEIAINEQNLADENDRRHMFKVDASRRTHNYDKFICTFLSMLAHQGVLGELVSQHLLPSKKVSGQSAANRISKQNSAASSAGANAGAAAGVTPKSQQQQQQPQTAASKNGKSPGKTPGRRRKGRNKCRKRK
What is the function of this protein?
Polycomb group (PcG) protein.  Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-118' (H2AK118ub1).  Does not deubiquitinate monoubiquitinated histone H2B.  Required to maintain the transcriptionally repressive state of homeotic genes throughout development.  The PR-DUB complex has weak or no activity toward 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase calypso, BAP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family. BAP1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to PcG response elements (PREs).
Protein: CLCC1_MOUSE
Sequence: MLCRLLLCECLLLITGYAHDDDWIDPTDMLNYDAASGTMRKSQVRSGTSEKKEVSPDSSEAEELSDCLHRLDSLTHKVDSCEKKKMKDYESQSNPVFRRYLNKILIEAGKLGLPDENKVEMRYDAEILLSRQTLLEIQKFLSGEEWKPGALDDALSDILINFKCHDSEAWKWQFEDYFGVDPYNVFMVLLCLLCLVVLVATELWTYVRWYTQMKRIFIISFLLSLAWNWIYLYKMAFAQHQANIAGMEPFDNLCAKKMDWTGSLWEWFTSSWTYKDDPCQKYYELLIVNPIWLVPPTKALAITFTNFVTEPLKHIGKGAGEFIKALMKEIPVLLQIPVLAILALAVLSFCYGAGRSVPMLRHFGGPDREPPRALEPDDRRRQKGLDYRLHGGAGDADFSYRGPAGSIEQGPYDKMHASKRDALRQRFHSGNKSPEVLRAFDLPDTEAQEHPEVVPSHKSPIMNTNLETGELPGESTPTEYSQSAKDVSGQVPSAGKSSPTVDKAQLKTDSECSPPGGCPPSKEAAVAAHGTEPVSSPCG
What is the function of this protein?
Seems to act as a chloride ion channel (By similarity).  Plays a role in retina development (PubMed:30157172).
What are the official names of this protein?
Chloride channel CLIC-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the chloride channel MCLC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes.
Protein: L10K_BOVIN
Sequence: MAQGQRKFQAQKPAKSKAAAAAASARNRGPRKGGRVIAPKKARIVQQQQLKKNLEVGIRKKIEHDVVMKASTSLPKKLALLKASTKKKEASSSTKMPA
What is the function of this protein?
May have a potential role in hypercalcemia of malignancy.
What are the official names of this protein?
Leydig cell tumor 10 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0390 family.
Protein: O1030_MOUSE
Sequence: MLAPKKMVRGNYSMVTEFILLGLTDRPELQPLLFVLFLVIYLITVGGNLGMMVLIRIDSRLHTPMYYFLASLSCLDLCYSTNVTPKMLVNFLSEKKTISYAACLVQCYFFIAMVITEYYMLAVMAYDRYMAICNPLLYSSKMSKGVCVRLIAGPYIYGFLSGLMETMWTYRLTFCGSNIINHFYCADPPLIRLSCSDTFIKETSMFVVAGFNLSNSLFIILISYLFILIAILRMRSAEGRRKAFSTCGSHLVAVTVFYGTLFCMYVRPPTDKSVEQSKIIAVFYTFVSPMLNPIIYSLRNKDVKHAFWKLVRRNVLSK
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 1030, Olfactory receptor 196-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.