PharMolix/UniProtQA huggingface dataset:
Protein: EFP_RICCK
Sequence: MKISANSIRTGNILVYSNDLWVVSRTPEHTQPGKGGAYVQVEMKNLKTGTKRNERFSSSDYLEKAELEQKDYQFLYFEGNDLVLMDIKHFDQINVPKEILEEKLPFLAENMIVKVEFYNEKPLNIELPPTVIIEISETDPVIKGATATASYKPAILTNGIKVKVPQYLEIGEKIVVKTDDMTYVERAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_CVP67
Sequence: MSFTPGKQSSSRASSGNRSGNGILKWADQSDQSRNVQTRGRRVQSKQTATSQQPSGGTVVPYYSWFSGITQFQKGKEFEFAEGQGVPIAPGVPSTEAKGYWYRHNRRSFKTADGNQRQLLPRWYFYYLGTGPHAKDQYGTDIDGVFWVASNQADINTPADIVDRDPSSDEAIPTRFPPGTVLPQGYYIEGSGRSAPNSRSTSRAPNRAPSAGSRSRANSGNRTSTPGVTPDMADQIASLVLAKLGKDATKPQQVTKQTAKEVRQKILNKPRQKRSPNKQCTVQQCFGKRGPNQNFGGGEMLKLGTSDPQFPILAELAPTAGAFFFGSRLELAKVQNLSGNPDEPQKDVYELRYNGAIRFDSTLSGFETIMKVLNQNLNAYQHQEDGMMNISPKPQRQRGQKNGQVENDNVSVAAPKSRVQQNKSRELTAEDISLLKKMDEPYTEDTSEI
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the betacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: NFUA_EDWI9
Sequence: MIRITEAAQEHFAKLLANQEPGTQIRVFVINPGTPNAECGVSYCPPDAVEANDRKLDFEQLSAYVDEISAPFLDDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLIERVEYILQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDYTLKEGIEKELLQRFPELKGVRDLTEHQRGDHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: IFNAD_BOVIN
Sequence: MAPAWSLLLALLLLSCNAICSLGCHLPHSHSLAKRRVLTLLRQLRRVSPSSCLQDRNDFAFPQEALGGSQLQKAQAISVLHEVTQHTFQLSSTEGSAAVWDESLLDKLRTALDQQLTDLQACLRQEEGLPGAPLLKEDSSLAVRKYFHRLTLYLQEKRHSPCAWEVVRAQVMRAFSSSTNLQERFRRKD
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-D.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPA_LACBS
Sequence: MPTLLRILRPPRSPFTRCLATFATPSSSGSSSRSKFTESLETGPGLDDFISEEVPDRVVLGNTKGPRLPSYLKTSIPSGASFNKIKKDLRGLGLHTVCEEARCPNIGDCWGGKPGATEAEGRSAATATIMLMGDTCTRGCRFCSVKTSRTPPPLDPHEPENTAEAISRWGLGYIVLTSVDRDDLLDGGAHHFAETIRKIKYKAPQILVEALTGDFAGSLDHVSIVAQSGLDVYAHNIETVEELTPFVRDRRATFRQSLKVLEHAKKSGVRITKTSIMLGVGETKEQVLAALKELRKIDVDVVTFGQYMRPTKRHMKVDRYVEPAEFDNWKEVAENLGFLYVASGPLVRSSYKAGEFYIENVLRGKNKAIGGLGISQLEGSEKGSMTGIDR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL1_BURTA
Sequence: MAKISKRRQAFAAKVDRQKLYPIDDALALVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEVVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPTALRTNLSALIEALQKAKPATSKGVYLRKIALSSTMGVGVRVDQGSLAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RS13_HALSA
Sequence: MSSEEQEDVDEDIQYFVRIGQTDLDGTKTVERALAELGGVGRRVARIVADEAGVDRTATMGGLEDDAIESVTDAVDSFTEHAPAWLANRQNDFYTGENQHITGTDVELTRDQDINRMRMIRSYKGIRHERGQKVRGQRTKSTGRTEGTIGVNVEAIKEEQAEDDAADGGEE
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13, HS13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: FA10_CHICK
Sequence: MAGRLLLLLLCAALPDELRAEGGVFIKKESADKFLERTKRANSFLEEMKQGNIERECNEERCSKEEAREAFEDNEKTEEFWNIYVDGDQCSSNPCHYGGQCKDGLGSYTCSCLDGYQGKNCEFVIPKYCKINNGDCEQFCSIKKSVQKDVVCSCTSGYELAEDGKQCVSKVKYPCGKVLMKRIKRSVILPTNSNTNATSDQDVPSTNGSILEEVFTTTTESPTPPPRNGSSITDPNVDTRIVGGDECRPGECPWQAVLINEKGEEFCGGTILNEDFILTAAHCINQSKEIKVVVGEVDREKEEHSETTHTAEKIFVHSKYIAETYDNDIALIKLKEPIQFSEYVVPACLPQADFANEVLMNQKSGMVSGFGREFEAGRLSKRLKVLEVPYVDRSTCKQSTNFAITENMFCAGYETEQKDACQGDSGGPHVTRYKDTYFVTGIVSWGEGCARKGKYGVYTKLSRFLRWVRTVMRQK
What is the function of this protein?
Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.  VAP cleaves the fusion proteins of Sendai virus, NDV, and influenza virus a at a specific single arginine-containing site, and plays a key role in the viral spreading in the allantoic sac.
What are the official names of this protein?
Coagulation factor X, Stuart factor, Virus-activating protease, VAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLP7_CYBJA
Sequence: LVSDASNTKSYISRVAQDGSKSKEIYSGKPTLYLIVRTPGPVGAKIPSKVQKVLQLLRLNKINSGVFVKLTETVYPLLKLLSPYTVIXQPSLQTVRQLVQKRATVTVTHANDEEPRQVKLNDNNLVEEKLGDEGIICIEDIIHETSHLATTFKTVTHFLDPFELNKDVVGYGPLAKLRKLEKQEAEKQRKTSNSGSAPILEIDIDDFVAQQN
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May act as a specificity factor that binds precursor rRNAs and tethers the enzymes that carry out the early 5' to 3' exonucleolytic reactions that generate the mature rRNAs (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein RLP7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GLK1_ARATH
Sequence: MLALSPATRDGCDGASEFLDTSCGFTIINPEEEEEFPDFADHGDLLDIIDFDDIFGVAGDVLPDLEIDPEILSGDFSNHMNASSTITTTSDKTDSQGETTKGSSGKGEEVVSKRDDVAAETVTYDGDSDRKRKYSSSASSKNNRISNNEGKRKVKVDWTPELHRRFVEAVEQLGVDKAVPSRILELMGVHCLTRHNVASHLQKYRSHRKHLLAREAEAANWTRKRHIYGVDTGANLNGRTKNGWLAPAPTLGFPPPPPVAVAPPPVHHHHFRPLHVWGHPTVDQSIMPHVWPKHLPPPSTAMPNPPFWVSDSPYWHPMHNGTTPYLPTVATRFRAPPVAGIPHALPPHHTMYKPNLGFGGARPPVDLHPSKESVDAAIGDVLTRPWLPLPLGLNPPAVDGVMTELHRHGVSEVPPTASCA
What is the function of this protein?
Transcriptional activator that functions with GLK2 to promote chloroplast development.  Acts as an activator of nuclear photosynthetic genes involved in chlorophyll biosynthesis, light harvesting, and electron transport.  Acts in a cell-autonomous manner to coordinate and maintain the photosynthetic apparatus within individual cells.  May function in photosynthetic capacity optimization by integrating responses to variable environmental and endogenous cues (PubMed:11828027, PubMed:12220263, PubMed:17533111, PubMed:18643989, PubMed:19376934, PubMed:19383092, PubMed:19726569).  Prevents premature senescence (PubMed:23459204).
What are the official names of this protein?
Transcription activator GLK1, GBF'S PRO-RICH REGION-INTERACTING factor 1, Golden2-like protein 1, AtGLK1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOA_LACSA
Sequence: MVREKITVSTRTLQWKCVESAADSKRLLYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRAKSEKISHEYSTIMGIQESVHEILMNLKEIVLRSNLYGTCEASICVRGPGYVTAQDIILPPYVEILDNTQHIASLTEPIELVIGLQIEKNRGYLIKAPNTFQDGSYPIDPVFMPVRNANHSIHSYENGNKEILFLEIWTNGSLTPKEALYEASRNLIDLLIPFLHTKEENLNLEGNQHMVPLPPFTFYDKLAKLTKNKKKMALKSIFIDQSELPPRIYNCLKRSNIYTLLDLLNNSQEDLMKMEHFRIEDVKQILGILEKNFVIDLPKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CAPP_AMAHP
Sequence: MASGKVEKMASIDAQLRLLAPKKVSEDDKLVEYDALLLDRFLDILESLHGSGIRETVQELYEHAAEYERTHDTKKLEELGNLITSLDAGDSIVIAKSFSQMLNLANLAEEVQLAYRRRIKKTKKGDFADESSAITESDFEETLRRLVDLKKSPEEIFATLKNQTVDLVLTAHPTQSVRRSLLQKHGRIRDCLSQLYAKDISPDDKQELDEALQRAIQAAFRTDEIRRVQPTPQDEMRMGMSYFHETIWKGVPKFLRRVDTALKNIGINERVPYNVPLIQFSSWMGGDRDGNPRVTPEVTRDVVLLARMMAANMYFTQITDLMFELSMWRCNDEVRARAQELHSQSKSDAKHYIEFWKQIPLSEPYRVILGDVRDKLYNTREHAHKLLANGSSDVPEESTFTHIDQFLEPLELCYKSLCASGDQPIADGSLLDFMRQVSTFGLSLVKLDIRQESDRHTEVMDAITTHLGIGSYRSWSEEKRQEWLLSELRGKRPLFGSDLPMSYEVADAIGTFRVLAELPNDSFGAYIISMATAPSDVLAVELLQRECGIKKPLRVVPLFEKLADLQSAAASMTRLFSIDWYKNRINGTQEVMIGYSDSGKDAGRLSAAWQLYKVQEQLIQVAKEYGVKLTMFHGRGGTVGRGGGPTHLALLSQPPDTIHGSLRVTIQGEVIEQSFGEEHLCFRTLERYTAATLEHGIDPPTSPKPEWRALMDEMAVITTKEYRSVVLQEPRFVEYFRSATPELEYGRMNIGSRPAKRKPGGGIETLRAIPWIFSWTQTRFHLPVWLGCGAAFKHVIEKDIKNLAMLKDMYNQWSFFRVTIDLLEMVFAKGDPGIAALYDKLLVKDELKPFGENLRKSYLEAQKFLLEIAGHKDPLDADPYLKQILRLRDPYTTTLNVFQVYTLKRIRDPSFHVTVRPHLSKEMDANSLAADLVKLNPTSEYPPGLEDTLILTMKGIAAGMQNTG
What is the function of this protein?
Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_TUPAK
Sequence: MSRRRRAKKRIICPDSIYDSRLINMLVNRVMKDGKKSLAYKIVYQTMDQIAEKTEQDPIQILEEAVRNTKPLVEVKARRVGGSAYQVPLEVNPERGTVLALQWVLAAARNRSGRSAIAKLTNELIDASKKTGGAIKKRDDVHRMAEANKAFAKFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ER_DROVI
Sequence: MSHTILLVQPGARPETRTYCDYESVNECMEGVCKIYEEHLKRRNPNTPTITYDISQLFDFIDTLIDISCLVYQKSTNTYAPYNKDWIKEKIYVLLRQAAFSPNA
What is the function of this protein?
Acts as an enhancer of the rudimentary gene.  Has a role in pyrimidine biosynthesis and the cell cycle.
What are the official names of this protein?
Protein enhancer of rudimentary.
What is the protein family that this protein belongs to?
Belongs to the E(R) family.
Protein: SGMR1_DANRE
Sequence: MSLIRTILKLVVVVGFLSLTVQFIRHWMANKQYVFTKEEVAKLAKQYAGQDHEQAFSKVVVELRRRYPGHILPDEDLQWVFVNAGGWMGSMCLLHASLTEYVLLFGTAVDTGGHSGRYWAEISDTIISGTFRQWKEGTTKSETYYPGDTIVHSAGEATSVQWSSGTWMVEYGRGFIPSTLGFALADTMFSTQDFLTLFYTARVYVKGMILEASTFLTESGVL
What is the function of this protein?
May function in lipid transport from the endoplasmic reticulum and be involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane.  May regulate calcium efflux at the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Sigma non-opioid intracellular receptor 1, Sigma 1-type opioid receptor, Sigma1-receptor, Sigma1R.
What is the protein family that this protein belongs to?
Belongs to the ERG2 family.
What are the subcellular locations of this protein?
Nucleus inner membrane. Nucleus outer membrane. Nucleus envelope. Cytoplasmic vesicle. Endoplasmic reticulum membrane. Membrane; Single-pass membrane protein. Note=During interphase, detected at the inner and outer nuclear membrane and the endoplasmic reticulum. Detected on cytoplasmic vesicles during mitosis (By similarity). Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum (By similarity).
Protein: LFTR_OLEA2
Sequence: MHLYALSEKLEFPDPQTASSEGLLAIGGDLSVARLVTAYANGIFPWYDDDTPILWWSPDPRCVLYPSQLHVPASLRRRINSGQFEVTLDTAFEAVIHACADAARPGQSGTWIVDEMIDAYMNLHEAGVAHSVEVWSRGAGDGRVLAGGLYGVALGGVFYGESMFYRRTDASKVAVVWLVRLLEFWGYRVVDCQQTTTHMLRFGAQEVSRACFLEELDRALRMPLRAGRWQIPDGFRPLRRATLPDENQ
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F237B_HUMAN
Sequence: MCFATRRWFYLHLGCMMLINLVNADFEFQKGVLASISPGITKDIDLQCWKACSLTLIDLKELKIEHNVDAFWNFMLFLQKSQRPGHYNVFLNIAQDFWDMYVDCLLSRSHGMGRRQVMPPKYNFPQKITGGNLNVYLRE
What is the function of this protein?
May be capable of activating GPR83 via the GNAQ signaling pathway.
What are the official names of this protein?
Protein FAM237B.
Protein: PYR8_ASPFU
Sequence: MDLVPSSTLWSIAQELALYLAFTVPTAFVIITTPKSSFLRLAWTPCLLYILYRFSLQVPSLTTSQFLNGVAAGQATVAALQCLNLLLITKLDERELVHAGLCIPSSSLLVRVACAWALLVNFRGIGTVWEVKNVPQHAAYLQKPKQHRLSRRRYVLRESAIIIWQYLLLDLIHMSTKDTPPGDLARLFGPGLEYRYLDATAEQWFGRVSVGIFSWLVPSRVCLNIVSRIYCLVLVVLRISAPESCRPSFGRVRDACTIRGFWGKFWHQSFRWPLTSVGSFVARDVLRLPRPSLLERYTNIFFTFFTSAVLHLACDAILGIPPSGSGAMPFFCVVPLAIMFEDGVQEVWRRVTGPSQGAVPFWQRLVGFLWVGSWMYATSPWYLYPAARQPPERTWMVPVSVVGEIGLRVAQKVLLVYGVVLYWAIGGEI
What is the function of this protein?
Acetyltransferase; part of the gene cluster that mediates the biosynthesis of pyripyropene A, a specific human acyl-coenzyme A:cholesterol acyltransferase 2 inhibitor (PubMed:20861902).  The first step of the pathway is the synthesis of nicotinyl-CoA from nicotinic acid by the nicotinic acid-CoA ligase pyr1 (PubMed:20861902).  Nicotinyl-CoA is then a substrate of polyketide synthase pyr2 to produce 4-hydroxy-6-(3-pyridinyl)-2H-pyran-2-one (HPPO) which is further prenylated by the polyprenyl transferase pyr6 to yield farnesyl-HPPO (PubMed:20861902).  The next steps consist of an epoxidation of farnesyl-HPPO to epoxyfarnesyl-HPPO by FAD-dependent monooxygenase pyr5 and a cyclization of the terpenoid portion by the terpene cyclase pyr4 to yield deacetyl-pyripyropene E (PubMed:20861902).  The 2 cytochrome P450 monooxygenases pyr3 and pyr9, and the 2 acetyltransferases pyr7 and pyr8 are involved in the conversion of deacetyl-pyripyropene E into pyripyropene A through several cycles of oxidation and acetylation steps (PubMed:20861902).  Pyr7 acetylates deacetyl-pyripyropene E to pyripyropene E which is oxidized to 11-deacetyl-pyripyropene O by pyr3, which is in turn acetylated into pyripyropene O by pyr8 (PubMed:21224862, PubMed:26019565).  Pyripyropene O is then oxidized to deacetyl-pyripyropene A by pyr9 (PubMed:21224862).  Deacetyl-pyripyropene A is finally acetylated to pyripyropene A by pyr8 (PubMed:26019565).
What are the official names of this protein?
Acetyltransferase pyr8, Pyripyropene synthesis protein 8.
What is the protein family that this protein belongs to?
Belongs to the wax synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NAC_AERPE
Sequence: MLPVNPRDLEKMMRRLGIKVEQLSADEARIVLGSGETMVFRSPTVIVMRAKGQPPMVYLVGDYTVEKPREETAAEITEEDVALVAEQAGVSMEEARKALEESGGDIAEAILRLKGEE
What is the function of this protein?
Contacts the emerging nascent chain on the ribosome.
What are the official names of this protein?
Nascent polypeptide-associated complex protein.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: RL33_XANCB
Sequence: MAKGKRDKIRMISSAATGHFYTTDKNKKNTPGKMEMMKYDPVVRKHVMYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TRPC_GEOKA
Sequence: MLEQILATKREEVETLTLPAPLPERKRRPFAAALRRPRRMLGLIAEVKKASPSKGIIRPDFDPVAIAKAYERAGADAISVLTDERYFQGHRRYLRAVKEAVNVPVLRKDFIIDRRQVEESVRLGADAILLIGEALPPETLEELYHEAYSLGLECLVEVHAKETLERIFDRFTPEIVGINNRDLHTFVTTLEATKTLAPLIPPSCVIVSESGIGSFNDVKTVKSYGAQAMLVGESLMRQDDVERAVYRLFGEEDGDDSN
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: FRMD8_XENTR
Sequence: MDGSETSHSSGLNDFLLRSSVSSGSRSMDVIVYLINDEIIQLTVDGLSVITAHELHKSIREALQLPETAQDVFALWLISPFLEVQLKPKHQPYKVCRQWHDLLARFTNCSSNDILQDEPFLQFRRNIFFPKARELQIAHERTLYLLYEEAKYNVLDGRYPCDVEDCELLGGLACRLELGPYNQNEHTPATIRPKLDSLFPPYLCKKRNGFFTTFKNKGGRQASFEQTVLNTYKEVKESSACTEEQAMKNHYREYLKKCHELPYYGCAFFHGVVDKPAQGFLNRSGRKPVSVAINLEGVSVIDRKEKHILISLTYPELSWDHTYPDEEEHILWLEFDGDAEGTPVNKLLKIYSKQAELMSGLIEYCIELSQTTESPASDFLPGNSQLSEKRSKLRRQESVLCNRMKHLNTIDYVEDGASIKRVKPKRTASFFTRQNTHYSAVQPSETPTET
What is the function of this protein?
Promotes the cell surface stability of RHBDF1 and RHBDF2 and prevents their degradation via the endolysosomal pathway.  By acting on RHBDF proteins, involved in ADAM17-mediated ligand shedding (By similarity).  May negatively regulate Wnt signaling (By similarity).
What are the official names of this protein?
FERM domain-containing protein 8.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane.
Protein: CPXP_ECOL6
Sequence: MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSHMFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKMANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSSSNSRSQ
What is the function of this protein?
Acts as an accessory protein in the Cpx two-component envelope stress response system.  Binds the periplasmic domain of sensor histidine kinase CpxA, inhibiting induction of the envelope stress response in the absence of inducer.  Aids in combating extracytoplasmic protein-mediated toxicity.
What are the official names of this protein?
Periplasmic protein CpxP.
What is the protein family that this protein belongs to?
Belongs to the CpxP/Spy family.
What are the subcellular locations of this protein?
Periplasm.
Protein: END4_MYCBT
Sequence: MLIGSHVSPTDPLAAAEAEGADVVQIFLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRVRIPSRKILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPVYLENTAGGDHAMARRFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDAVDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAVKAAGAPVICETADQGRKDDIAFLRERTGS
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: NADD_BACTN
Sequence: MRMAESNKLKTGIFSGSFNPVHIGHLALANYLCEYEELDEVWFMVSPQNPLKAGTELWPDDLRLRLVELATEEYPRFRSSDFEFHLPRPSYSVHTLEKLHETYPERDFYLIIGSDNWARFDRWYQSERIIKENRILIYPRPGFPVNENGLPETVRLVHSPTFEISSTFIRQALDEKKDVRYFLHPKVWEYIREYIRQSITDN
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: Y290_BURCH
Sequence: MCHAAPARPEGARGRPPSGDNFSGAARSKPVGAAFEQRARQFLERHGLGFVAANVTMRGGELDLVMREPDGMLVFVEVRARRSTRHGGATASVGWRKRRRLVAAALQFWSRHGAGAACRFDVVAFEAGRLAWLRDAFRTDDA
What are the official names of this protein?
UPF0102 protein Bcen2424_0290.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RECA_MYCSJ
Sequence: MAPQAPDREKALELALAQIEKSHGKGSVMRLGDEVRAPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGIAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDILVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKITGALSNSGTTAIFINQLREKIGVMFGSPETTTGGKALKFYASVRMDVRRIETLKDGTDAVGNRTRVKIVKNKVSPPFKQAEFDILYGKGISKEGSLIDMGVEHGFIRKSGSWFTYEGEQLGQGKENARKFLLENGDVANEIEKKIKEKLNIGAVVTADDVLPAPVDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_SHEPC
Sequence: MRPLTPRQAEILELIKRNIADTGMPPTRAEIATRLGFKSANAAEEHLKALAKKGCIEIMPGTSRGIRLPAEEEVVVEYGLPLIGQVAAGEPILAQEHVEQYYQVDPSMFHPTADFLLRVKGDSMKNIGILEGDLLAVHKVQQARNGQVVVARVDDDVTVKRFEKKGNLVYLYAENEDYSPIKVDLSCQSLTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ALLA_SALG2
Sequence: MKLEVLPLDQKTFSAYGDVIETQERDFFHINNGLVERYHDLAKVEVLEQDRTLISINRAQPAAMPIVVHELERHPLGTQAFVPMNGEAFVVIVALGDDKPDLSTLRAFISNGRQGVNYHRNVWHHPLFAWQTVTDFLTVDRGGSDNCDVESIPTHELCFT
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.