PharMolix/UniProtQA huggingface dataset:
Protein: TET3B_XENLA
Sequence: METQPASVPCVLPQDVYEFSEDRESLGRLRVSEMPSELNGGGDGSKGDGAAVVATEVSQQSNKKRKRCGVCVPCLRKEPCGTCYNCVNRSTSHQICKMRKCEQLKKKRVVPMKGVEAVDKDDAKNQAKEQVPSVKNCSESILVDGPKTDQMEAGPVNHVQEGRLKQECDSTLPSKGSEDLANQLLMEANSWLSNTAAPQDPCNKLNWDKPIIPNHIAANNNSNLEDAKNLVAFSAVAEAMSNYGMPASGTPSSISMQLYEKFNYETNQDNSGHSEGNAPSCPEDLNTLKEALALAKHGVKPPNCNCDGPECPDYLEWLENKIKSTGKGSQESPFPSLGQVSKKLVQKSYHKEQVLNLENTNVTCPSGNLPFSQNALSLAKEKNISLQTAIAIEALTQLSSALPQTNNEYPNAPSQPLINHNDQLTHFPTAKGNQLPMLPLSCNELFQNQQAQLYTGKNALPVPQSPRQASWEQNKKPGYQESEYIPENLSQSSSVLPSDASTPQKKEFLQQWVQNADLLKSPSDPMTGLKQLLGNTDEYIKSAFKGPEGLSKKIKNVKSKHTIKSIKKESADFTKMSPDQQLSQLLQGNDFHRNTQAALQQHLHHKRNLFVDSNTMEACTQEQQNWWVPNSQQAPVSKTTEKPVKERKKRRQSPSQKQVEPKPKPPRKQVQIKKPRVKEGNAVFMPVSQISLDSFRRVEKEENQVKELDLENSLPINVQPDLLGSQSIQLTGSQANLENQKTVNTQETCNENQTSIGKANNFALCVNKTNSLVAKGRCPTPSTGDSSSGQGDSANQHTNLTDVPGQNDLSCIDDKFEDLIKQFAAEFGEDFSLPGSEVPSQNGERPPKQQTSGVPQFKMPFPSQLPSENATHSNPALSNNLLTHNASHKFDSLFSSKSPKQIKIESSGAITVVSTTCSYSEENQHLDGTPTKSELPFNPTLSGFLESPLKYLTSPTKSLIDTPAKMAQAEFPTCDCVEQINEKDEGPYYTHLGSGPTVASIRELMEERFGEKGEAIRIEKVIYTGKEGKSSRGCPIAKWVIRRQSEDEKLMCLVRQRAGHHCENAVIIILIMAWEGIPRALGDSLYDDISGTITKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFRLIGDNPKEEEFLKDSFQDLATKVAPVYKMLAPQAYQNQANNEDVAIDCRLGLEEGRPFSGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRMIGKIAEDEQLHVLPLYKVSTTDEFGSEERQLEKIRKGGIQVLSSFPREVRKLSEPAKSCRQRQLDAKKATAEKKKLQKEKLVSPDKTKQEPSDTKTCQQNPGVPQQQTKPCVKVEPSNHYNTFKYNGNGVVESYSVLGSCRPSDPYSMNSVYSYHSFYAQPNLPSVNGFHSKFALPPFGFYSFPNNPVVPNQFMNYGTGDARNSGWMNNSFEKKPELQSLADGMNQSYGSELPEQNYRRSSEVPHHYSLQNSNSQKSVGVPHRTTPAPMETTPYSNVPCYNKVIKKEPVCDPLVDPFQRSNSVHSQSPGVNHSLQTNDLSYKANGALPSSGRTNKEGPCSMFLPSDKNGLEKRDYFGVHSNVPGLKEKQWTPYGIDVPVGQRDSLDSQCSGKVWSSCKLSDSPAVMPSTVQDKNWTGRQASLNQGVKEPMPFQEKLWNSVAASGRCSTTPNDRSSVTPCAELQDKNWMSFPNPAVNSLKTDSSQNHWDPYSLDDNMDDGQSKSVKEEEDEEEIWSDSEHNFLDGNIGGVAVAPGHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARVKEEEAAKLGIKQEVKSLGKKRKWGGAATTETPPVEKKDFIPTRQAATSLTDSTTTAFSYAYTKVTGPYSRFI
What is the function of this protein?
Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.  Conversion of 5mC into 5hmC probably constitutes the first step in cytosine demethylation.  Selectively binds to the promoter region of target genes and contributes to regulate the expression of numerous developmental genes, including pax6, rax, sox9 and six3.  May also contribute to the regulation of target genes in ways that do not require its enzyme activity.
What are the official names of this protein?
Methylcytosine dioxygenase tet3-B.
What is the protein family that this protein belongs to?
Belongs to the TET family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Detected on chromatin, where it binds to target gene promoters.
Protein: NQRD_CHLTA
Sequence: MTTNKSYLTYFTDALWINNQPLIAILGICSALAVTTTVTTALTMGFAVSFVTGCSSFVVSLLRKITPESVRMIAQLIIISLFVILIDQFLKAFFFTISKTLSVFVGLIITNCIVMGRAESMARHVSPIPAFLDGLGSGLGYGWVLVCISIIRELFGFGTILGFRVIPEILYTSAAHPDGYENLGLMVLAPSAFFLLGIMIWIVNIIRAPKTKR
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNG1_GIBZE
Sequence: MAGQHPPAGEYGEEWARDLRVQFEGLLRDKRMNDLRNTSRQSSPSLGDQSPHMRSSPFPSDNRPSGSQGPALPSYAALRHLPKIPSPPAAGDRDSQKFRNLLISLSLTPTKYENPGLLDEALQTIPLDRIYGEAEEETQVLQAQAESMGDGRKPEWGYQDCVIRALLRWFKRSFFSWVNNPPCPSCLSPTIAQGMTAPTPEESACGALRVELYRCSAQHCGAYERFPRYGDVWRLLQTRRGRVGEWANCFSMLCRAVGGRVRWVWNAEDHVWTEVYSDHQKRWVHVDACEEAWDNPRLYAEGWGKKMSYCIAFSIDGATDVTRRYVRKNQHASERNRCPEEVLLYVMQEIKNMRRSNMNKDERFRLEKEDTREDKELRGYVVASIAQAVTDLVPGSPGGSNHTTASGSDTKLPAEQPGRQTGTSEWLTAQQQQSHSRYQQPRDPSHRRPLP
What are the official names of this protein?
Protein PNG1.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase-like superfamily. PNGase family.
Protein: DPO1_LACLA
Sequence: MENKDRLLLIDGSSVAFRAFFALYNQIDRFKAPNGLHTNAIFAFHTMLSSLMERIEPTHVLIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDIIGTLDKMAEAPNVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLTPAQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVDSLKASKMKENLIADKEMAFLSQQLATINTKAPIEIGLDDTLLKGKKVDELSQFYDEMGFAQFKSKLLAEAGGEVTDEKVVDEIDFEIVTDGSISEKVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKNIDLLTKMKFPENTYDFKKNRVLLSHLDIELPLVKFDAMLAKYLISTTEDNKISTIARLFNSGHLATDEEIFGKGTKIALPDDAVLFEHLARKIKVLALAKEKMMAELLENEQEHLLSDMELPLAEVLAKMEITGIAVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPKQLGVILFEKLQLPVGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKGLIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPSKDSLLLSSDYSQIELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNFGVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRRRKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALSARDFKSKLLLQVHDEIILDVPLEELDEIKVLVKQTMEEAIELAVPLKVDENTGKTWYEAK
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: ANR55_MOUSE
Sequence: MRQATMDFSTSSVFDQHKGDSSEEVDLAMVYQAASNGDVNSLTSVIREDPSILECCDSEGCTPLMHAVSGRQVDTVKLLLKMGANINTQDAYGRTSLCLATYLGWLEGCVSLLRNGAKHNIPDKNGRLPLHAATAEPDVRLLIVLLQQSSLSEINHQDTEGMTPLHWAAFHNRPQHTQMLLKKGADPTLVDKDFKTALHWAVQSGNRILCSIILSHRQGPSIINYDDESGKTCVHIAAASGFGDIINDLAKVPECNLQALDVDDRTPLHWAAASGKAECVQSLLDLGMDSNLRDINESTPLAYALYCGHTACVRLLSREGRAEPARPLPSQNSQPQKKEGRFSMLNQIFCKNKKEEQKAHQKDQSRARPKEEETSEVNDIIATFDSVVDTNCQGQPGDQVDMVVFKKRTSENSKYLLPEKKSLARKGLPPIRTQSLPPITLGGHFLTASQGAVSHAGLNAGPQHTAQRSQKSRSEQDLLNNRTGCPVSLENPWKGDTRQVFSCKAWTVSSSDKLLDRLFAGQPGHQELSGPPHLPHLHNPSSGQALQHLSPNRPKIRDLPFTRNSLAPLPDQKFLSGEPLRTNRVLPAIPSQRGHDPSPAGESQRGHDPPRAEESGGSSSPTHDEN
What are the official names of this protein?
Ankyrin repeat domain-containing protein 55.
Protein: KRA81_MOUSE
Sequence: MYYTGAEGSVFPGCYWGSYGYPLGYSVGCGYGSTYSPVGYGLGYGYNGCGAYRRYWPFALY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 8-1, HGTp type I F, High-glycine/tyrosine protein keratin, HGT keratin.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 8 family.
Protein: OR4F5_HUMAN
Sequence: MVTEFIFLGLSDSQELQTFLFMLFFVFYGGIVFGNLLIVITVVSDSHLHSPMYFLLANLSLIDLSLSSVTAPKMITDFFSQRKVISFKGCLVQIFLLHFFGGSEMVILIAMGFDRYIAICKPLHYTTIMCGNACVGIMAVTWGIGFLHSVSQLAFAVHLLFCGPNEVDSFYCDLPRVIKLACTDTYRLDIMVIANSGVLTVCSFVLLIISYTIILMTIQHRPLDKSSKALSTLTAHITVVLLFFGPCVFIYAWPFPIKSLDKFLAVFYSVITPLLNPIIYTLRNKDMKTAIRQLRKWDAHSSVKF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4F5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATB_XANC5
Sequence: MFDIGVGELTLIAVVALVVLGPERLPKAARFAGLWVRRARMQWDSVKQELERELEAEELKRSLQDVQASLREAEDQLRNTQQQVEQGARTLHDDVSRDIDIRASATPVATPLELAHADLSASPDVDATAGVTDAAGAAHTAPVIAQAQPIAPAPHQTLVPAPHDTIVPAPHAAHLASAPEPVAVAPVDAGTPAAWTPSAPAKLQEKQP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NSPC_VIBCO
Sequence: METLQDIGTNMLKDELRTPYFMIDEAKLIANLEIAKHLKEISGVKMVLALKCFSTWGVFDIIKPYLDGTTSSGPFEVKLGYETFGGETHAYSVGYSEEDVKEVIDICDKMIFNSQSQLAAYRHLVEGKASLGLRINPGVSYAGQDLANPARQFSRLGVQADHIDESVFDSINGVMFHMNCENKDVDAFIGLLDAISERFGRYLDKLDWVSLGGGVFFTWPGYDVEKLGAALKAFAERHAVQLYLEPGEAIITKTTDLVVTVVDIVENGMKTAIVDSATEAHRLDTLIYKEPASVLEASDKGQHEYVIGSCSCLAGDQFCVAKFDEPLQVGQKLHILDSAGYTMVKLNWFNGLKMPSVYCERKNGQIQKINQFGYEDFKRTLSLWSIE
What is the function of this protein?
Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.  Involved in the regulation of biofilm formation and motility.
What are the official names of this protein?
Carboxynorspermidine/carboxyspermidine decarboxylase, CANS DC/CAS DC, CANSDC/CASDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL1A_HUMAN
Sequence: MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA
What is the function of this protein?
Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems (PubMed:26439902).  After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex (PubMed:2950091, PubMed:17507369).  Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4 (PubMed:17507369).  In turn, mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways (PubMed:14687581).  Within the cell, acts as an alarmin and cell death results in its liberation in the extracellular space after disruption of the cell membrane to induce inflammation and alert the host to injury or damage (PubMed:15679580).  In addition to its role as a danger signal, which occurs when the cytokine is passively released by cell necrosis, directly senses DNA damage and acts as signal for genotoxic stress without loss of cell integrity (PubMed:26439902).
What are the official names of this protein?
Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). Recruited to DNA damage sites and secreted after genotoxic stress.
Protein: IL10_TRIVU
Sequence: MPTWMLLFCLLCVTSSNLSSALEDNCKTFSTTLPNMLRELRAAFSSVKTYFQTRDKLETKLIDKSLLEELKSYLGCQALSEMIKFYLEEVMPRAEENELDVKEDVGSLGEKLKALRLRLKRCHRFLPCEDNSRVVKQVRNTYKELQEQGVYKAMGDFDIFIGYMEEYLTMHIGK
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PBL21_ARATH
Sequence: MTCCFSCLNPRTKDIRVDIDNARCNSRYQTDSSVHGSDTTGTESISGILVNGKVNSPIPGGGARSFTFKELAAATRNFREVNLLGEGGFGRVYKGRLDSGQVVAIKQLNPDGLQGNREFIVEVLMLSLLHHPNLVTLIGYCTSGDQRLLVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAARGIEYLHCTANPPVIYRDLKSANILLDKEFSPKLSDFGLAKLGPVGDRTHVSTRVMGTYGYCAPEYAMSGKLTVKSDIYCFGVVLLELITGRKAIDLGQKQGEQNLVTWSRPYLKDQKKFGHLVDPSLRGKYPRRCLNYAIAIIAMCLNEEAHYRPFIGDIVVALEYLAAQSRSHEARNVSSPSPEISRTPRRDL
What is the function of this protein?
May be involved in plant defense signaling.
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL21, PBS1-like protein 21, Protein ALTERED SEED GERMINATION 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GATB_CANGA
Sequence: MYKNSIRTRPLKRFISNHAKGKFALDPAYKLKCGLEIHTQLNTRYKLFSYTSNEAENLTISPNTSTSHYDISLPGTQPRLNYEAVLYATKLALSLDSDINLISQFDRKHYFYGDQPQGYQVTQHYKPFAKNGKLTLYGAYEDINENEKTIRIEQLQIEQDTGKSLYASGADMTTMIDLNRSNVPLIELVTKPDFEDLKQVRAFIKKYQDLVRRLNICTGNLETGSMRIDVNLSVNDFARVELKNLPNTSSIMNAIKFEYERQLHIIKNGEGERLLRDTETRGWTGSETVKLRSKETSIDYRYMPDPEIPFITIADDVVHKVKSTLPVSADALLREFMNKPYNLPIKHAKILCISGNQNEMYDHEQLRKYYKDVCVHYQKEYPDDNLKIPSNWILNEFIGNLNKLETKLNEIYEILTPSTFFELIRLMKQGVITGNSSKLLLFHIVNNVKTGVFTKSSQINLKQLINEYELQAADQINEHELEEICRSIIDDIKDEKLLQNLISGKKKTSLKFLVGQGMRLSQGRLNPNELEKMFRQVLDIKW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RLMD_SHEDO
Sequence: MAQFFKEKANKSKQLSPKLSLNVTQLDHLGAGMAQHQGKVVFIPQALPGERVSVQLTDQKKSFAKAKLIKIEQQSPERADASCPHYGHCGGCDLQHLALDAQQNHKQQSLNELMVKFSGSPVIDPQVQAAPLVSPPWHYRRRARLATYFNNNDKSLKLGFRALSSKQIVPIKQCPVLAEPLSALINPFSLLLARLKAKASLGHLELTQADNGTFAVLRVTKVLPAADIRALASFALTQGINLLLQDDSGALTDVMTMAPAEDEGATQVEQSALTLPEYALSQGQVSCQFTPGNFVQVNAEVNQRMVEQAVNWLDLQVGERVLDLFCGVGNFSLALANRGQNLDGLEVIGVEGVPEMVQQARENAKRNNLANLSFYHADLSADLSNEKWLGKIDKLLLDPARAGAFESLQWLQKMKPKKVVYVSCNPASLARDSSVLLSQGYQLKQLSMIDMFPQTHHIEAMALFEIAT
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: SAM15_MOUSE
Sequence: MSEVSGDYNSDSDESLSLQPKRTKSGKLHNANADTLFEVSSKLSPNTDRDPGNVGNVPLEPTRTRKGDLVPVGKNHEVPDLQRQDVSVGVFKGPPTRTGTQLPTKIDPEQKTPDIRSEKLRKSVEEEALPPSKMTKSEKKQKESIKEKSTEPYEVTKPKFPDRKLRKSTEEADLKPHFKSTEQSGTEQPEQTKFPDKKLRQSTKKKVSGPLEDFEEESRRPIDEASLELSQKRPLKASKKAQKSSFDEKFPEMLEQITVELLDDQEETQEESIKEKVPEPLGDRKPSAQKHKLRKSSERSKLKDTLIEPSKDKDPGLQTQTEFPKEKLIKTTEKTGDKPQQITDPDIQEKSQPEPTEKNLELPNKPKPEEERDLPKEDKPESSKPNYPAGKDKLALPAKIKTEFIVGSPRESVESFSTLYETQEFLKDLQTDMNELFPIVDASESQTELRDSTVLPQEVELLGRKETKPSLTPEFEHLTWSPERVAEWISDLGFPQYKECFTENFINGQKLIHVNCSNLPQMGITDFEDMKAISYHTRVLLGIEEPLFSRSISLPYRDNKGLFFEQKGHSGVKSDSLTLAKFVEAAGLQEYNPEIKAEEKKEDALPENSLEENEELYEAT
What are the official names of this protein?
Sterile alpha motif domain-containing protein 15, SAM domain-containing protein 15.
Protein: ARLY_SALSV
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTADEQRQLEEALNVLLEEVRANPQQILQSDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKETVRELLTANRQLQSALVETAQANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDTLKRLDVSPLGCGALAGTAYEIDREQLAGWLGFTSATRNSLDSVSDRDHVLELLSDAAIGMVHLSRFAEDLIFFNSGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRLRCQDAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEALPLADLQKFSRVIGDDVYPILSLQSCLDKRAAKGGVSPQQVAQAIDDARARLAL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRI_SULIN
Sequence: MISSSKRDELIVSKIRKGTVIDHIPAGRALAVLRILGIRGSEGYRVALVMNVESKKIGRKDIVKIEDRVIDEKEASLITLIAPSATINIIRDYVVTEKRHLEVPKQIRGLIKCPNPQCITNNDVEAESRFTTISIKPLKLKCEYCEIYITEEDVIRQIL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: EFP_WIGBR
Sequence: MIIYYSANQSKSGLKILLKNEPCLILENQFVKPGKGQPFNRIKIKKLISGKIFTKIFKSNEKLIYADVLDVKVKSLYKDKKYWNFIKKENFEQFKISKKNLGEKYKWIIEQLECIVTFWDENPINITLPRFVDIKVCNANFDIKGDTIKSGNKYIILTTGAIIKAPIFIRSEEIVRVDTNLGEYVSRIK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-35 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_ACTSZ
Sequence: MDQLEMKKMAAQAALQFVQPDSIVGVGSGSTVNCFIEALGAMRDQIKGAVAASKASEELLRKQGIEVFSANDVSSLDIYVDGADEINPQKMMIKGGGAALTREKIVASLTKNFICIVDSSKQVDVLGSTFPLPVEVIPMARSQVARKLVALGGSPEWRQGVVTDNGNVILDVHNFPIMNPPEMEKELNNVAGVVTNGIFALNAANTVIVGTPEGAKIIK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: ERMP1_XENLA
Sequence: MESTVDGLTIRRPRYNVSAESASGYRREAGVREEKKPRQRDAGFGAAVPVLLLLYVLSVRGLVHISLRQLVTPGGHSTGFNASTAREYLQQITSIDSRTAGSPENEIIAVNYLLGKIKDIEEKINSVHRITVDVQRPTGTFSIDFLGGFTSYYDNITNIAVKLEPEHRAEHAVLANCHFDTVANTPGASDDAVSCAVMLEILGSLSSSSKPLKHAIIFLFNGAEENILQGSHGFITQHPWAKMVRAFINLEAAGVGGKELVFQTGPENPWLVQAYASAAVHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTWDRILTESIQRAGDNILGVLHYLATSSQLAESSQFRHGNMVFFDVCGLFVLSYPARLGTIINYITAAVTLFYISKKMIKYKQGGTNYVRDLVYGLIITLVSWVSALVTVLIIAVLVSLAGKALSWYTHFYVSIFLYGSAAVAKFILVHSLAKTYFFAGASSQYLGDLFFDISLITWCIPLVLLTQSGLCSAYFFAAWIIFPLLTKLLLQPDIIHQGSPYKFTAVYLLGLFPPYLHTMYHVWAVFEMFTPILGRSGTEIPPDIVLGFLIIACTIILITYFISFIYLLKSTKKIIVTLAVLSVLTLLLVCSGMFFPYSSSNDSPKPKRIFLQHTTRTFHSLTGEVVKRDSGIWINGFDYTGISYVTPHIPELNETVRAPCDDAPLCGFPWYFPVHHLIRKNWYLPAPPAPINEHTDFKLVSREEMSWGATRLFFEVKGPSHMTVYVRPNTNTVLSSWSLGDGIPVASGETDYFIFYSHGLYAPAWKFWIELKNSAKESKGIVTVAVGSHYFFGDSRNSPDLETLELKFPDWSFPSSWVCTYDLYEY
What are the official names of this protein?
Endoplasmic reticulum metallopeptidase 1, FXNA-like protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RPOZ_CAMJR
Sequence: MDKRIEEVAAKALEKMGNDRYRLSLVVAKRAEQLANGATPLVDFDKNKNKLADIALYEIAENKITLEGLVETNR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CYB_REIMX
Sequence: MTNIRKKHPLLKIINDSFIDLPAPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTSTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGMYYGSYTFMETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVVVHLLFLHETGSNNPSGLNSDADKIPFHPYYTIKDILGVILLLMVLMTLVLFFPDILGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAILPLLQTSKQRGLTFRPITQTLFWILAANLLVLTWIGGQPVEHPFILIGQLASISYFTIIIILMPVAGMIENNLLKFTH
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TPMT_PSEPK
Sequence: MEPAFWQQRWADNQIGFHQAQVNPYLQTYWPQLQLAPGSRVLVPLCGKSLDLAWLAGQGHRVLGVELSRRAVEDFFREHGLEAEVRQQGAFEVWRSGDVQLWCGDFFALRAEDVADCVGLYDRAAVIALPVQMRARYMQLLSGLLPANCRGLVVTLEYDQSLLAGPPFSVRDEELRQGFAGWQVEQLEAVDVIEDSPKFVQAGASSLLERVYQVSR
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_RICCN
Sequence: MMEVPREIIEKLEIFQKLVKKWNKSINLVSDNTIHNFWQRHILDSLQLIQYIDNKEIHLVDIGSGSGLPGIVLSIAGVAQVSLIEADLRKCIFLEKASKISNNNIQIINQRIEKVEIDCSILTCRAFSNLNTIFNCIKNISVREKFLLLKGKNYLTEIVEAKERWLFGYLIHQSITCEEGKILEVSNLTKMI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.