PharMolix/UniProtQA huggingface dataset:
Protein: NEGR1_CHICK
Sequence: MVPLVRGAGGSHQWLAAVLLGLCCLLPAGRLAAPGGDFPGAAADSLVVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGSDKWSVDPRVSIATANRREYSLQIQDVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVSPKIFRISSDIVVNEGSNVTLVCLATGKPEPSISWRHISPSAKPFESGQYLDIYGITRDQAGEYECSAENDVSVPDVKKVKVTVNFAPTIQELKSSGVMLGGNGLIRCEGAGVPAPVFEWYRGERKLISGQQGITIKNYSTRSLLTVTNVTEEHFGNYTCVAANKLGMTNASLPLNPPSTAQYGITGDAEVLFSCWYLVLTLSSLTSIFYLKNIILH
What is the function of this protein?
May be involved in cell-adhesion.  May participate in the regulation of neurite outgrowth in the developing brain.
What are the official names of this protein?
Neuronal growth regulator 1, Neurotractin.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: DEUP1_RAT
Sequence: MENQAHTTAGASPCEAELQELMEQIDIMVSNKKLDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLVMTQNYEGQLQTLKAQFSKLTNNFEKLRLHQMKQNQSHRKEASNKDETPFELSSLNQKIEEFRAKSREWDKQEILYQTHLVSLDAQQKLLSEKCNQFQKQAQNYQTQLNGKQQRPEDSSPETPRLVCESSPGCEATQRDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKNELQSRDDLLRIIEMERLHLHRELLKMGELQTVQDNRKRVESSYSPSTKEPERKRKELFSVVSDQPNHEKELNKMRSQLYQEEDLCSEQERMRNEISELTQELHQKEVTIATIMKKAALLERQLKIELEIKEKMLAKQQISDRRYKAVRTENTHLKGMMGDLDPARYLTVDFSNKEHSRHTSINKLEYENERLRSDLAKLHINGKAAWSNQSSYEGAGAYIYQSQLKTETGGDRISEDCEMNRSPTPLSPLPFQTKEMTSPLAGDNEVLPLSPPDISFRASLAAQHFLMEEEKRAKELEKLLNTHIDELQRHTEFTLNKYTKLKQSRHI
What is the function of this protein?
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells.  Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles.  Probably sufficient for the specification and formation of the deuterosome inner core.  Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).
What are the official names of this protein?
Deuterosome assembly protein 1, Coiled-coil domain-containing protein 67.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the deuterosome.
Protein: YCCT_ECO57
Sequence: MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLLRGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLENEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASLPQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQPSS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: LEU1_SHIFL
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVTNYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKTQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: TTCA_BRUMB
Sequence: MNAFDADITEHADSSGCHPLFRDVPATVEFNKLRKRLLRLTRQAIEDFAMVKPGDRWMVCLSGGKDSYGLLALLLDLKWRGLLPVELLAVNLDQGQPNFPKHILPDFLTRYGIEHRIEYQDTYSIVTDKLPETSTYCSLCSRLRRGNLYRIAREEGCSAIVLGHHREDILETFFMNLFHGGRLAAMPPKLLNDEGDLMVFRPLAYAAEDDLEKFANAMQFPIIPCDLCGSQDGLQRNAMKAMLIDIEKRMPGRKDTMIRALTNVRPSHLLDRKLFDFAGLMANGEKGSDDALW
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP18_HUMAN
Sequence: MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL
What is the function of this protein?
Participates in the second step of pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor 18, PRP18 homolog, hPRP18.
What is the protein family that this protein belongs to?
Belongs to the PRP18 family.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.
Protein: MATK_IRICR
Sequence: MEELQGYLEKDRSRPFLYPLLFXEYSYALAHDRGLKGSLFYEPTEVFGYDSKSSLALLKRFVIRIYQQNYFLSVVNDSNKNRFVSHHHNNFXYSHXYSQMISEGCAILVEIPFSLRLXSYFEKKEIPKSHNLRSIHSIFPLSEGXLLHLXHVSDILIPHPIHMGILVQILQCWIQDVPLLHFLRFFLHKYHNWNSFLITPKKSIYVFSKENKRLFWFLYNSYVSECEFLLVFPRKQSSYLRLTSFGLFLERRHFHVKMEHLQMQHLILIVVCRDYFQGTLWSFKDPFMHYVRCQGKAVLASKGTHLLMKKWKYNFVNLWQYYFHFWYQSYRIHINQLSNYSFYFLGYLSSLLKNSLTVRNQMLENSFLMDTVTNKFETIVPVIFLIGSLSKAQFCTVSGHPISKPIWADLSDSEIIERFGRMCRNLSHYHSGSSKKQGLYRIKYILRLSCARTLARKHKSTVRTFLRRLGSGLLEEFFTEEEQVLSLILPKTIPFTFYGSHKERIWYLDIIRINDLVNHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FBRS_MOUSE
Sequence: MFEKYPGKMEGLFRHNPYMAFPPAVPGLPPGLPPAVSFGSLQGAFQPKNTNPELPPRLGPVLSGLPQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPGQELSHPASLFTATGAVHAAANPFTTAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSSAVFAQKESPGAPPAFASPPDPWGRLHRSPLAFPAWVRPPETARTPGSDKERPMERREPSVTKEEKDRDLPFSRPQLRVSPATPKARAGEEGARPAKESVRVKEERKEEAAAAAAAAAAAAAAAAAAAAAAAATTGPQGLHLLLERPRPPPFLGPSLPERCAGFPEPTWLAGPPRLARPPRFYEAGEELTGPGAMAAARLYSLDPAHPLLYSRLAPPPPPTATPGTPHLLSKTPPGALLGAPPPLVPAPRPSSPPRAPGPARADR
What are the official names of this protein?
Probable fibrosin-1.
Protein: PHE1_RHDS2
Sequence: AMDKSAKAPQITIFDHRGCSRAPKSETGGTATKDDQMMVKVSQV
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
Phycoerythrin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the phycoerythrin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: CHS5_MEDSA
Sequence: MVSVSEIRNAQRAEGPATTLAIGTANPTNCVEQSTYPDFYFKITNSEHKTELKEKFQRMCDKSMIKRRYMYLTEEILKENPSVCEIMAPSLDAWQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLIVCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPSDTHLDSLVGQALFGDGAAALIVGSDPVPEIEKPIFEMVWTAQTIAPDSEGAIDGHLREAGLTFHLLKDVPGIVSKNINKALVEAFEPLGISDYNSIFWIAHPGGPAILDQVEQKLALKPEKMKATREVLSEYGNMSSACVLFILDEMRKKSAQDGLKTTGEGLEWGVLFGFGPGLTIETVVLRSVAI
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 4-2, Naringenin-chalcone synthase 4-2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: PSBT_PLAOC
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GPSB_BACC2
Sequence: MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFEQLKQQNARLKRELEEQKLAVTQVPQQPVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: REX_DESAP
Sequence: MKALRIPEATVTRLSIYSRFLERLEQRGITTVSSSEIAKGVGVSPAQVRKDLAYFGEFGTRGVGYNVKDLIHYILKILGLTRPWNVILVGAGNLGTALCTYRGFIDRGFNIVGVFDNDLTKIGKRIHDLEVLPLERMPEVIEQHDVKIAIIAVPLGSVQDIADQLVGHSLKALLTFGPVVVDVPGDVVVRNVDLAVKLEILTFNLVFKELHSII
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_PARUW
Sequence: MKGLVKKISAPGLWMENLPIPSHVKDDEVLIKTIKTSICGTDVHIYKWDAWAQKNVPVPLVIGHEFIGEIAEFGKNVKGFKIGERVCGEGHIVCNQCPNCRMGRKHVCMHTKGLGYHISGCFAEYFVLPAENVFSLPPSISDDLGAIFDPYGNAVHTTLAFNLIGEDVLITGAGPIGIMAAAIAKQAGARHIVITDVNDYRLDLARTMGVSHAINVNRESLDNFMQSLGIKYGFTVGLEMSGHPDGLKTLTEKIRHGGNIALLGILPPATSIDWNLVIFKMLTLKGIYGREIFSTWYQMVHLLEIGLNLAPIITHHFSVDNFEKGFEVMLSGQSGKVILDWV
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_ECO81
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPSMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_RHIME
Sequence: MSDIAERVKKIVIDHLGVDAEKVSEGASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAADSILTVGDAVKFIEKAQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein AcpP, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_LEUMM
Sequence: MTQKHGKNYVAAVAKVEAEKAYALNDAVSLVKEIDFAKFDASVEVVFKLNVDTRQADQQLRGAVVLPNGTGKDKTVVVFAQGDKAKEAEAAGADVVGAADLVQRIQGGWLDFDVAVATPDMMAQVGRVGRALGPKGLMPNPKTGTVTMDVTKAVSDAKGGQVTYRTDRDGNVAVPVGRVSFEEGKLAENIKSIAETVLKARPAAVKGTYVQHVSISSTFGPAVTLDINTL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MBTD1_HUMAN
Sequence: MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELLDGEDYNFLQGASDQESNGSANFYIKQEP
What is the function of this protein?
Chromatin reader component of the NuA4 histone acetyltransferase complex, a multiprotein complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A (PubMed:27153538, PubMed:32209463).  The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) by promoting homologous recombination (HR) (PubMed:27153538).  MBTD1 specifically recognizes and binds monomethylated and dimethylated 'Lys-20' on histone H4 (H4K20me1 and H4K20me2, respectively) (PubMed:19841675, PubMed:27153538, PubMed:32209463).  In the NuA4 complex, MBTD1 promotes recruitment of the complex to H4K20me marks by competing with TP53BP1 for binding to H4K20me (PubMed:27153538).  Following recruitment to H4K20me at DNA breaks, the NuA4 complex catalyzes acetylation of 'Lys-15' on histone H2A (H2AK15), blocking the ubiquitination mark required for TP53BP1 localization at DNA breaks, thereby promoting homologous recombination (HR) (PubMed:27153538).
What are the official names of this protein?
MBT domain-containing protein 1.
Protein: RUTG_ECOLI
Sequence: MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
What is the function of this protein?
May function as a proton-driven pyrimidine uptake system.
What are the official names of this protein?
Putative pyrimidine permease RutG.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCST_XANAC
Sequence: MTQKTILNDTHRALGAKMVDFGGWDMPIHYGSQLDEHHQVRRDAGMFDVSHMTVVDLHGARVREFLRYLLANSVDKLKVSGKALYTCMLNPQGGVIDDLIVYYMTEDFFRLVVNAATREKDLQWIGEQAARFDVRVEERSDFAMIAVQGPSARTKVIDLLDPADTAAASKLGRFAALQTRSRDGIELFLARTGYTGEDGFEIVLPQQAAVAFWNALLAQGVKPAGLGARDTLRLEAGMNLYGQDMDDGVTPYEAGLAWTIALDEGRDFIGRSVLESQKAQGAPRQLIGVVMDEKGVLRHGQTVLTANGEGEILSGTFSPTLGKAIAFARVPAGSIEQLRVDIRGKQVPLRAVKFPFVRDGQAQPGVLGD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: SYT_MYCMM
Sequence: MSVPAQPAPGADGGDPRQPIRVPAGTTAAAAIGEAGLPRRGAPDAIVVVRDAEGKLRDLSWVPDADAEVTPIAANTDDGRSVIRHSTAHVLAQAVQDLFPQAKLGIGPPITDGFYYDFEVLEPFTPDDLQALEKRMRQIVKEGQLFDRRVFESKDQAREELANEPYKLELVDDKSGDPDVMEVGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTKHIPAFKLTRSSAAYWRGDQKNASLQRIYGTAWESQEALDKHIELIEEAQRRDHRKLGVELDLFSFPDEIGSGLAVFHPKGGIVRRELEDYSRRKHTEAGYQFVNSPHITKAQLFHTSGHLDWYADGMFPPMQIDAEYNADGTVRKPGQDYYLKPMNCPMHCLIFRARGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRVRGLTMDDAHIFCTREQMRDELRSLLRFVLDLLSDYGLTDFYLELSTKDPDKFVGSDEVWEEATNVLAEVGAESGLELVPDPGGAAFYGPKISVQVKDALGRTWQMSTIQLDFNFPERFGLEYTAADGTRQRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAPVQAVGIPVADEHVAYLEQVAAQLKSHGVRVEVDTSDDRMAKKIVHHTNQKVPFMLLAGDRDVQADAVSFRFGDRTQINGVPREAAVAAIVDWISRRENATPTAELVKVDSGE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_YERPY
Sequence: MSETFIYPQANLIAGVDEVGRGPLVGAVVTAAVILDPNRPIVGLADSKKLSEKRRLSLYDEITEKALSWSLGRAEPEEIDQLNILHAAMLAMQRAVSGLHIVPDYVLIDGNRCPKLQMPSLAVVKGDSRVAEISAASILAKVTRDREMTELDLLFPEYGFAQHKGYPTAFHLEKLAALGATVHHRRSFGPVKRVLGLV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX36_HUMAN
Sequence: MASWLPETLFETVGQGPPPSKDYYQLLVTRSQVIFRWWKISLRSEYRSTKPGEAKETHEDFLENSHLQGQTALIFGARILDYVINLCKGKFDFLERLSDDLLLTIISYLDLEDIARLCQTSHRFAKLCMSDKLWEQIVQSTCDTITPDVRALAEDTGWRQLFFTNKLQLQRQLRKRKQKYGNLREKQP
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box only protein 36.
Protein: RS16_NOSP7
Sequence: MIKLRLKRFGKKREASYRIVAINNLARRDGRPLEELGFYNPRTDEVRLDVPGIVKRLQQGAQPTDTVRRILVKANVFEQVSATAAS
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RS17_METBF
Sequence: MARDIGLNIPAPSEECNDSYCPFHGTLSVRGQILVGTVVSSKMDNTVVIERQYMKLVPKYQRYEKRRSKVHAHNPPCISAKVGDIVTIAECRRISKTKSYVVVKAEVPK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PUS7_MOUSE
Sequence: MEMTSTSLKRGCLVVEDNDSVTPHDETKKQKVSEGCLTSSQDGVENDGLHRSENEPGPPEAESTVKDDENSSAQVQEEEEEEEEEDGLSEAGEEEEAESFADMMKHGLTELDVGICKFVSSHHGFSGILKERYSDFVVHEIGKDGRISHLDDLSVPVDEEDPPEDALTVLTAEDRQQLEELQLFKNKETSVAIEVIEDTKEKRTVIHQAIKSLFPGLETKTEDREGRKYIVAYHAAGKKALANPRKHSWPKSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITVQEIAVLKISAQRLAHLNKCLMNLKLGNFSYQKTPLKLGALQGNHFTVVLRNITGTDEQVQQAMQSLRETGFINYYGMQRFGTTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVKCREEWAKTKDPASALKKLPVKRCVEGQLLRGLSRYGMKNIVSAFGIIPRNNRLMYIHSYQSYVWNTMVSRRIEEYGLRPVPGDLVLKGATPTYIEEDDVDNYSIHDVVMPLPGFDVIYPKHKISEAYREMLAADNLDIDNMRHTIRDYSLSGAYRRIIIRPQSVSWEVVAYDDPKIPLFNTDVDNLEGKPPPVFASEGKYRALKMDFSLPPSTYATMAIREVLKMDTSIKNQTQLNTSWLR
What is the function of this protein?
Pseudouridylate synthase that catalyzes pseudouridylation of RNAs.  Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex.  Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3'.  Acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions.  Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing.  In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types.
What are the official names of this protein?
Pseudouridylate synthase 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAK_GEOSM
Sequence: MSRVIGIDLGTTNSCVAVMEGGEPVVIANAEGSRTTPSMIAFAESGERLVGQQAKRQAVTNPENTLYAIKRLIGRKFDTEAVKKDIAISPFKIVKADNSDAWVEVRGQKYSPPEISAMVLQKMKKTAEDYLGETVTDAVITVPAYFDDSQRQATKDAGKIAGLNVLRIINEPTAAALAYGLDKKKDEKIAVFDLGGGTFDVSILELGEGVFEVKSTNGDTFLGGEDFDQKIIDHIADEFKKDQGIDLRGDKMALQRLKEAGEKAKCELSTSLETDINLPFITADASGPKHLTMKLTRAKLESICAELIANLEGPCRTALKDAGLSASDIDEVILVGGMTRMPIVQKKVQDIFGKVPNRGVNPDEVVAIGAAIQGGVLRGDVKDVLLLDVTPLSLGIETLGGVLTKLIDKNSTIPCRKSQVFSTAADNQPAVSIHVLQGEREMAADNKTLGNFELSGIPSAPRGVPQIEVTFDIDANGIVHVSAKDLGTGKEQSIRITASSGLSKEEVEKMVREAEAHAADDKKKRELIEAKNQADNLIYQTEKSLTEFGDKIDASEKQKIEEGVAALKKALEGSDADEIKKASDSLMQASHKLAEAVYAKTQGAGAEGSEQPHGEQEAGGAAKGETVVDADFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: EST5B_DROPE
Sequence: MYCAKLILLLGCFWISSSASDPADPLLVDLPNGKLRGRDNGNYYSYESLPYAEPPVGDLRFEAPQPYKQQWTDTFDATQPPVSCMQWDQFIRGDDKLAGNEDCLTVSVYRPKNSSRNSFPVVAQIHGGAFMFGGASQNGHENFMREGNLILVKISYRLGPLGFVSTGDADLSGNFGLKDQRLALLWIKQNIASFGGEPENILVIGHSAGGGSVHLQVLREDFSKVAKAAISFSGNALDPWVVQQGGRGRAFELGRIVGCGQASDSVTLKKCLKSKPASEIVSAVRNFLVFAYVPFTPFGPVVESPDAPEAFISQHPVDIIKSGKFAQVPWAVTYTTEDGGYNAALLLEEQASSGREWIVDLNDRWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDLQRLFTDVLFKNSTEISLDLHRKHGKSPVYAFVYDNPANTGIGQGLAQRTDINFGTVHGDDYFLIFENIVREPQLRSDEETISRNFLKMLNDFVLSENGTLAFGTCVFQDNVGSSKLQLLSITRNGCENLELESFP
What are the official names of this protein?
Esterase-5B, Est-5B, Carboxylic-ester hydrolase 5B, Carboxylesterase-5B.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1056_ARATH
Sequence: MGAIHDEPFTACGDETECFGGNREGSQSFHSSSTKEENLEDSYLYLVHQRSMSIFFWDERANTGVAGAVDEGKIIDFEFLNPDEKRIIEEHANKEREEGVDVILVNFDRREYMLNLRRWNMGTSPLYILVSGRYNVVKGCRLKEGNEIRIWSFHFDDQLNLAMVPLTPTESG
What are the official names of this protein?
Putative B3 domain-containing protein At1g05615.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRYB2_RAT
Sequence: MLKLLLLLALSPLASLVHAAPCPVKQRVGIVGGREASESKWPWQVSLRFKFSFWMHFCGGSLIHPQWVLTAAHCVGLHIKSPELFRVQLREQYLYYADQLLTVNRTVVHPHYYTVEDGADIALLELEIPVNVSTHIHPISLPPASETFPSGTSCWVTGWGDIDSDEPLLPPYPLKQVKVPIVENSLCDRKYHTGLYTGDDVPIVQDGMLCAGNTRSDSCQGDSGGPLVCKVKGTWLQAGVVSWGEGCAEANRPGIYTRVTYYLDWIHRYVPQRS
What is the function of this protein?
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.  Plays a role in innate immunity.
What are the official names of this protein?
Tryptase beta-2, Tryptase-2, Mast cell protease 6, rMCP-6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Tryptase subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Released from the secretory granules upon mast cell activation.