PharMolix/UniProtQA huggingface dataset:
Protein: MND2_YEAST
Sequence: MARALRDISLFNDIRKDQNSAGAKHERYNMRDLRSKKNQHVNGIDDYEDDSLDRFIRRKKSRVVKYIPSLSAYNVFNEFPYYPTSASQLLDGKLDEFLMLSEQYKSRLPKIRKLGWNRFKPIGINKTMYELEMLRSRARAQNAEGNNEEDFRQHDSREEDPRNNGSIGRVILPHILQENEEYDTGEGVTGLHSMPNDSMAILANNSANNSQNEEVSEEDEISYDYDAEFDHVVDEDDNEEGEVPGEGVEGIEVQRERIVPDDLLMRPTSLSRSLQQFVEEAHHLDRNPYDIDSDNDGEDSKVELDMNPDFEDDVGREHDYNSEYSQEPTSYGGITPDLASNWRNWTRERITSLDELMERRARQQRGQD
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome.  In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition.  In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.
What are the official names of this protein?
Anaphase-promoting complex subunit MND2, Meiotic nuclear division protein 2.
What is the protein family that this protein belongs to?
Belongs to the APC15 family.
Protein: GPDA_STRP7
Sequence: MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_YERPB
Sequence: MATYHHWTVGQALALFDKPLLELLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLESERLMQVEQVLESAKKAKAAGSTRFCMGAAWKNPHERDMPYLAKMVEGVKALGMETCMTLGSLSKQQAHRLADAGLDYYNHNLDTSPEFYGSIITTRSYQERLDTLNEVRDAGIKVCSGGIVGLGETVRDRAGLLVQLANLPKPPESVPINMLVKVKGTPLENNAEVDAFEFIRTIAVARIMMPSSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPDEDKDLQLFRKLGLNPQQTATSHGDREQQQALTEQLLHGDTAQFYNAAV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: HEMH_RICBR
Sequence: MNINKKRIAIVLFNLGGPDSLKSVKPFLFNLFYDKAIINLPNPLRYIIAKLISTTREKKSQKIYSLIGGKSPLLEETEKQKLALAENLKQATNEDFNIFINMRYASPKIEETIKQIKEYNPTEVILLPLYPQFSTTTTGSSVKNFLSNFNINIPVKVVCCYPVEENFIKAHTALIKEKIFDKNSRVLFSAHGLPQKIIDAGDPYSFQVEETVKAVVKELNIKDLDYKVTYQSRVGPVEWLKPNTEDEIEIAGKQNKNIIIVPIAFVSEHVETLVELDIEYKLIADKYKIKYNRTPTLSTNKIFIKSLTSILLKFINKKEDDFLVASSNGERICPDKFSKCLCFTSFPPMRESSK
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA1_NEIMA
Sequence: MSQKLILVLNCGSSSLKGAVLDNGSGEVLLSCLAEKLNLPDAYITFKVNGEKHKVDLSAHPDHTGAVEALMEELKAHGLDSRIGAIGHRVVSGGELYSESILVDDEVIAGIEKCIPLAPLHNPAHLLGLRAAQSIFKDLPNVVVFDTSFHQTMPEVAYKYAVPQELYEKYGLRRYGAHGTSYRFVADETARFLGKDKKDLRMVIAHLGNGASITAVANGESRDTSMGLTPLEGLVMGTRSGDIDPSVFGFLAENANMTIAQITEMLNKKSGLLGISGLSNDCRTIEEEAAKGHKGAKLALDMFIYRLAKYIGSMAVAAGGLDALVFTGGIGENSDIIRERVIGYLGFLGLNIDQEANLKARFGNAGVITTADSKAVAVVIPTNEELMIAHDTARLSGL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase 1, Acetokinase 1.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_BRUC2
Sequence: MARYVFITGGVVSSLGKGIAAAALAALLQARGYRVRIRKLDPYLNVDPGTISPYQHGEVFVTDDGAETDLDLGHYERFTGRPANQQDNITTGRIYRNIIEKERRGDYLGATVQVIPHVTDEIKNFVLEGNEDYDFVLCEIGGTVGDIEAMPFLEAIRQLGNELPRGTAVYIHLTLMPYIPAAGELKTKPTQHSVKELRSIGIAPDILLVRADREIPESERRKLSLFCNVRESAVIQALDVATIYDVPIAYHKEGLDSEVLSAFGIDPAPKPRMDRWEEVSHRLHNPEGEVTIAVVGKYTGLKDAYKSLIEALHHGGLANKVKVNLDWIEAQVFESEDPAPYLEKVHGILVPGGFGERGAEGKILAAKFARERKVPYFGICFGMQMACIEAARNLVGIEDASSSEFGPTREPVVGLMTEWLKGNMLEKRAAAGDLGGTMRLGAYEAVLKPDSKIAQIYGSTDIHERHRHRYEVNIDYKDRLEAAGLNFAGMSPDGVLPETVEYADHPWFIGVQYHPELKSRPFEPHPLFASFIEAAIEQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: LLDD_ECODH
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DPOL_HBVD4
Sequence: MPLSYQHFRRLLLLDDEAGPLEEELPRLADEGLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSSVPVFNPHWKTPTFPNIHLHQDIINKCEQFVGPLTVNEKRRLQLIMPARFYPNFTKYLPLDKGIKPYYPEHLVNHYFQTRHYLHTLWKAGILYKRETTHSASFCGSPYSWEQKLQHGAESFHQQSPGILSRPPVGSSLQSKHQKSRLGLQSQQGHLARRQQGRSWSIRARVHPTARRPFGVEPAGSGHTTNFASKSASCSYQSPVRKAAYPTVSTSKRRSSSGHAVDFHNLPPSSARSQSERPVFPCWWLQFRNSKPCSDYCLSHIVNLLEDWGPCTEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGNYRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSRIFDHQHGTMQNLHDYCSRNLYVSLLLLYQTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTAVTNFLLSLGIHLNPNKTKRWGYSLHFMGYVIGSWGSLPQDHIVHKLKECFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLYKQYMNLYPVARQRSGLCQVFADATPTGWGLAMGHQRMRGTFQAPLPIHTAELLAACFARSRSGANILGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLCRPLLRLPFRPTTGRTSLYAVSPSVPSHLPDHVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: CYSP3_OSTOS
Sequence: AWQYFALEGVVTGGNYRKQGCCRPYEFPPCGRHGKEPYYGECYDTAKTPKCQKTCQRGYLKAYKEDKHFGKSAYRLPNNVKAIQRDIMKNGPVVAGFIVYEDFAHYKSGIYKHTAGRMTGGHAVKIIGWGKEKGTPYWLIANSWHDDWGEKGFYRMIRGINNCRIEEMVFAGIV
What is the function of this protein?
Expression of the protease correlates with blood-feeding and suggests a role for the protease in blood digestion.
What are the official names of this protein?
Cathepsin B-like cysteine proteinase 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: NANE_MYCPU
Sequence: MFEKKLFFVSCQALKGEALYGKDIVVKLAKAAIQGGAQGLRTSQIKNIKALIRANFNVPIIGIIKQNYPNSDVYISPTLKEMKKLIKTGVQIIAIDATLRKRPKESLNQIVDYFFKHKKSHQLLMADCSSIEDVNNAIKLNFDIIGTTLRGYTEDTKNFSNTDDNYLFLRQVLKICQQNKKYLIAEGGFNSPQNAKDALDIGANAVVVGSAITRPQFITKMFYEKINS
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: TAGU_HALH5
Sequence: MKKALIAIGLILGTITVAIIGYGIYLYSSIQNTAGEMHEPLDRGDKSDKRDVAFDISAQDPFSILIAGVDSREDTHAGRSDTLIVLTVNPKEESIKMLSIPRDTRTEIVGRGTDDKINHAYAFGGAQMTIDTVENFLDIPIDHYVSINMDGFTQLVDALGGVSVENSFAFSQNGYQFEEGEIFLETGDEALAYARMRKQDSRGDFGRNDRQRQIVEAVIKQSAQFSSITKAGAILDAVGESVRTDLQLDGMWELQSNYRGAAKNIEQLEITGEGTRINNIYYLIIPQEEIARVQGELKSHLELS
What is the function of this protein?
May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).
What are the official names of this protein?
Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU.
What is the protein family that this protein belongs to?
Belongs to the LytR/CpsA/Psr (LCP) family.
Protein: IXTPA_THET8
Sequence: MLRGMKVVLATGNPGKVRELKEGLAPLGWTLLTLADFALRMPKEEGATFLENALLKAAYVAKATGLPALADDSGLEVYALGGEPGVYSARYGGRATDRERNVYLLERMRHLKGEERKARFVAVLVLAYPDGHAEAYEGSVEGVILEAPRGEGGFGYDPLFYVPEAGKTFAEMGLEEKARYSHRGKALRALLEAYKDGPPPREVSKLE
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: TRPD_LISMC
Sequence: MEILLQKVYDQENLSKEEMTMIATEIFEGRLSKTKIAAFLMALKVKGETAEEMAGIAQAMQRVAIQVAFPAGTAMDNCGTGGDKSNSFNISTTSAFVLAAAGIPVAKHGNRSISSRSGSADVCQELGIDINMRPEDMTYLLEKVGIAFLFAPHVHPNMKYVMDVRKELGTPTIFNLIGPLTNPVHLETQLMGIYRRDLLEQTAEVLGQLGRKRAVVLNGAGFMDEASLAGENHYALYENGEVHLYTLRPEDVGLTSYPLEAITGGEAKENAAILRSVLDGEPGAYLDTVLLNAGFGLFANGKVTTVQEGVDLARDLIRSGLAKQKLADLITYQKEVLAK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SECA1_MYCPA
Sequence: MLSKLLRLGEGRMLKRLKRVADYVNTLSDEVEKLTDAELRAKTDEFKKRHADGESLDDLLPEAFAVAREAAWRVLDQRPFDVQVMGAAALHFGNVAEMKTGEGKTLTSVLPAYLNGIGGKGVHVVTVNDYLAKRDSEWMGRVHRFLGLDVGVILAQMTPDERRVAYNADITYGTNNEFGFDYLRDNMAHSLDDLVQRGHNFAIVDEVDSILIDEARTPLIISGPADGASNWYLEFARLAPLMEKDVHYEVDLRKRTVGVHELGVEFVEDQLGIDNLYEAANSPLVSYLNNALKAKELFHRDKDYIVRDGEVLIVDEFTGRVLYGRRYNEGMHQAIEAKEHVEIKAENQTLATITLQNYFRLYDKLSGMTGTAQTEAAELHEIYKLGVVPIPTNKPMIRTDQSDLIYKTEEAKYIAVVDDVVERYQKGQPVLIGTTSVERSEYLSRQFQKRRIPHNVLNAKYHEQEAGIVAVAGRRGGVTVATHMAGRGTDIVLGGNVDFLTDQRLRERGLDPVETPDEYEAAWHEELPKVKAEAAAEAKEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDELMRRFNGAALEAMLNRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRKNVLKYDEVMNQQRKVIYAERRRILEGENLKEQALEMVRDVVTAYVNGATAEGYAEDWDLDALWTALKTLYPVGIDYATLTRRDADGGFDDLTREELLEALLKDAERAYATREAELEEIAGEGAMRQLERNVLLNVIDRKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQREGYDMFMAMLDGMKEESVGFLFNVTVEAVPAPQVAPVQTPEGLAELGAPAEQGGTATAARDEAPTQLRAKGIDNEAPAMTYSGPSEDGSAQVQRNGGDAKTPAGVPAGASRRERRAAARQQGRGAKPPKSVKRR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: YIDD_YERPE
Sequence: MASPLSPGSRILIGLIRGYQLVISPLLGPRCRFHPTCSHYGIEALRRFGMIKGSWLTLKRVLKCHPLNSGGDDPVPPKLDDNREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YHCE_ECOLI
Sequence: MKRIITGCLLLNFAMAAQAECNISSSIQNIDYGKRSAAMRQVDRGKTTQLADRTITLVMQCDQDAHIRVQLNTANISNNGFGFGPNGSLNLIASDAFSGSNNLDLALASGKNDNPGSTGTASISTSPNNWLVFMQNGQEVVIDSGKSVSLTLTMAPAFKDEGELTDMTDITGNLTVLVEAK
What are the official names of this protein?
Putative uncharacterized protein YhcE.
Protein: ERA_STRPI
Sequence: MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGDDMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSRLVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMKRDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWVKVKKNWRDKKLDLADFGYNEKEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: TRPA_ECO81
Sequence: MERYESLFTQLKERKEGAFIPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEVLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAECEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKAFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: AMPD2_RAT
Sequence: MASYPGPGKSKAKYPFKKRASLQASAAAPEARSGLGASPLQSARSLPGTAPCLKHFPLDLRTSMDGKCKEIAEELFSRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRGLWERDVVLEREFQRVIISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQSPDTPVSADAPVHPPALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRRDPDEHCPEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNKISGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVNHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEEVGIVMSPGP
What is the function of this protein?
AMP deaminase plays a critical role in energy metabolism.  Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle (By similarity).
What are the official names of this protein?
AMP deaminase 2, AMP deaminase isoform L.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: ATPD_SHEB9
Sequence: MAELTTIARPYAKAAFDFAIEQDAVDSWAEMLTFAALVSENETMQPLLAGSLASTKLAALFISVCGEQVNVQGQNLIKVMAENGRLKVLPAVSQLFTEYRNEWAKEVEADVVSATELSSEQQQQISISLEKRLARKVKLNCSTDAALIAGVIIKTGDLVIDGSVRGKLSRLSDKLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AMPA_CHLMU
Sequence: MVLLYSQASWDKRSKADALVLPFWMKNVKAQEAAVVDEDYKLVYQNALQNFSGKKGEAVFLFGNDKTKEQKIVLLGLGKSEEVSGTAILDAYAHVTTVLRKAKCKTVNILLPTISQLRFSVEEFLTNLAAGVLSLNYNYPTYHKVDASLPLLEKVTVLGIVPKVGDKIFRKEESLFEGVYLTRDLVNTNADEVTPEKLAAVAKGLAGEFASLDVKILDRKAILKEKMGLLAAVAKGSAVEPRFIVLDYQGKPKSKDRTVLIGKGVTFDSGGLDLKPGKAMITMKEDMAGAATVLGIFSALASLELPINVTGIIPATENAIGSAAYKMGDVYVGMSGLSVEIGSTDAEGRLILADAITYALKYCAPTRIIDFATLTGAMVVSLGEAVAGFFANNDVLARDLAEAASETGEALWRMPLVEKYDRALHSDIADMKNIGSNRAGSITAALFLQRFLEDNPVAWAHLDIAGTAYHEKEELPYPKYATGFGVRCLIYYMNKFLSK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_HUMAN
Sequence: MAGPRVEVDGSIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMIRDLCDGQLEGAEIGSTEITFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSELHLKGGTNAEMAPQIDYTVMVFKPIVEKFGFIFNCDIKTRGYYPKGGGEVIVRMSPVKQLNPINLTERGCVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGNGIIIIAETSTGCLFAGSSLGKRGVNADKVGIEAAEMLLANLRHGGTVDEYLQDQLIVFMALANGVSRIKTGPVTLHTQTAIHFAEQIAKAKFIVKKSEDEEDAAKDTYIIECQGIGMTNPNL
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase, RNA terminal phosphate cyclase domain-containing protein 1, RTC domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: ULAE_ECO27
Sequence: MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDDRLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: KITH_ROSCS
Sequence: MTRLSSGGRIEVICGCMFSGKTEELIRRLNHVRLARQRLIAFTPRRDTRYRLGSLVSHNGLSVEARVIDSIRDTPAHLNTDIHVVAVDELHLLDDPPDAAREVCQDLADRGLRVIVAGLDQDFRAQPFPAMAQLMAVAEQVDKLYAICVRCGAYATRSQRLIDGKPAPADAPTIVVGGQELYEARCRACYEPAR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_MAGMM
Sequence: MPRNYLFSSESVSEGHPDKMADQISDAILDALLAQDPLSRVACETMVSTGFCTIAGEITTKAVIDYQKIARETINAIGYTSADTMGYSGDTAAIFVALDKQSVDIAQGVNEGEGIDLDQGAGDQGIMFGYACTETDVLMPMPIYYAHRLMEKHAELRKSGELAWARPDAKSQVTVRYVDDKPVSVEAVVISSQHSPDVDHDTIEKEIIEKVIRAVIPAELLHEGTQYFINPTGRFVIGGPVGDAGVTGRKIIVDTYGGMGSHGGGAFSGKDPSKVDRSSAYMGRYVAKNIVAAGLAEKCEIQVAYAIGVSQPMSVMVDTFGTGKLDDEAITELVKKHFDLRPKAIVQQLDLLRPIYKKSAAYGHFGRELPEFTWERTDKAAALRADAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_XANOR
Sequence: MAKGKRDKIRMISSAATGHFYTTDKNKKNTPGKMEMMKYDPVVRKHVMYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: IFNW2_HORSE
Sequence: MALLPSLLTALVVYELWPCGALGCDLPQNHILVSRKNFVLLGQMSRISSAICLKDRKDFRFPQDMADGRQFPEAQAASVLHEMLQQIFSLFHTERSSAAWNTTLLDELCTGLLRQLEDLDTCLEQEMGEEESALGTVRPTLAVKRYFRGIHLYLKEKKYSDCAWEIVRMEIMRSFSSSANLQGRLRMKDGDLGSP
What are the official names of this protein?
Interferon omega-2, Interferon alpha-II-2.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.