PharMolix/UniProtQA huggingface dataset:
Protein: SAHH_NOVAD
Sequence: MASVLDAQNDYVVADIGLADFGRAEIRIAETEMPGLMALREEFGASQPLKGARITGSLHMTIQTAVLIETLVALGAEVRWATCNIFSTQDHAAAAIAAAGIPVFAVKGESLAEYWDYVGSIFDWGDQTANMILDDGGDATMFALWGARVEAGEPLFEPSNAEEIEFVRALKEFLKRKPGYLTMSVAHIKGVSEETTTGVHRLYQIAKDGKLPFPAINVNDSVTKSKFDNLYGCKESLVDAIRRATDVMLAGKVACVAGFGDVGKGSAASLRQGGARVMVTEIDPICALQAAMEGYEVVTMEEAVQRCDIFVTATGNEDVITAEHMKAMKPMSIVCNIGHFDSEIQISALNNYKWTEIKPGTDLVEFPDGKQIIILAKGRLVNLGCATGHPSFVMSSSFTNQVLAQIELFTKNAEYKNEVYVLPKHLDEKVAALHLEKLGVKLTKLSKKQADYIGVSQEGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1246_METM6
Sequence: MYVPEEIIETIKMIEYQNLDIRTTTLGVNLKDCADKDLDLLKENIYNKITSYGGNLVETANKVSQKYGIPIVNKRISVTPIGLIMGSTLKGLSDEEAIDACVEVGITLDNIAKEVGVDFIGGYSALVQKRATPEEKMLIRSIPKLMTKTDRVCASVNVATTKAGINMYAVKKMGEIVKETSEITKDAIGCAKIVVFCNAPEDNPFMAGAFHGPGEGDAVINAGVSGPGVVRAVVEQLKGKDIGTVSDEIKKTAFKITRMGELVGKEVASELGVDFGIVDLSLAPTPAIGDSIANILEAVGLERCGTHGTTAALAMLNDAVKKGGAMASSNVGGLSGAFIPVSEDAGMIEAVEVGALRLEKLEAMTCVCSVGLDMIAVPGKTPASTLSAIIADEMAIGMINKKTTAVRIIPVPGKDVGDSVEYGGLLGTAPIMPVSEFSSEEFIERGGRIPAPIQSLTN
What are the official names of this protein?
UPF0210 protein MmarC6_1246.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: LGT_CERSK
Sequence: MSYIPFPNISPELFSIELFGVTFALRWYALAYIAGLLIGWRLVLRMIRAERLWSFGPPMTEDQLERLLTWVILGVILGGRMGFVLFYQPAHYLAHPLDILKVWEGGMSFHGGFLGVMTALVAFCLKERISILPVADLLAAATPPGLFLGRIANFINAELWGRPTTLPWGVAFPGEAAQSCPGIEGICARHPSQIYEAGLEGILLFAVLSLLVWRRGWLHWPGSVSGVFLAGYGATRFLVEFVRQPDAQFVSAGNPLGLAWQISGYGLTMGQILSLPMILLGLYLILRSRRTA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTMC2_METAC
Sequence: MTNTEIFEKLTNAIVTQNIAGCVQLTQEALDAGIPPIDIITKGLSPGMKIIGDKFEAAEIFLPQIMMSAKAMSSAMEILTPELEKSKVEGEETGLAITFVAEGDIHDIGHRLVTTMLGANGFEILDLGVDVLNENVVEEAAKHKGQKVILVGSALMTTSMLGQKDLMDRLREEKLRDSLKCMFGGAPVSSKWIEEIGADATAENAAEAAKVALNIMK
What is the function of this protein?
Acts as a methyl group carrier between MtmB and MtbA.
What are the official names of this protein?
Monomethylamine corrinoid protein 2, MMCP 2.
What is the protein family that this protein belongs to?
Belongs to the methylamine corrinoid protein family.
Protein: DDI1_YEAST
Sequence: MDLTISNELTGEIYGPIEVSEDMALTDLIALLQADCGFDKTKHDLYYNMDILDSNRTQSLKELGLKTDDLLLIRGKISNSIQTDAATLSDEAFIEQFRQELLNNQMLRSQLILQIPGLNDLVNDPLLFRERLGPLILQRRYGGYNTAMNPFGIPQDEYTRLMANPDDPDNKKRIAELLDQQAIDEQLRNAIEYTPEMFTQVPMLYINIEINNYPVKAFVDTGAQTTIMSTRLAKKTGLSRMIDKRFIGEARGVGTGKIIGRIHQAQVKIETQYIPCSFTVLDTDIDVLIGLDMLKRHLACVDLKENVLRIAEVETSFLSEAEIPKSFQEGLPAPTSVTTSSDKPLTPTKTSSTLPPQPGAVPALAPRTGMGPTPTGRSTAGATTATGRTFPEQTIKQLMDLGFPRDAVVKALKQTNGNAEFAASLLFQ
What is the function of this protein?
Aspartic protease (PubMed:21266539).  Appears to act as negative regulator of constitutive exocytosis (PubMed:10330187, PubMed:12051757).  May act at the level of secretory vesicle docking and fusion as a competitive inhibitor of SNARE assembly (PubMed:12925750).  Acts as a linker between the 19S proteasome and polyubiquitinated proteins like the HO endonuclease and UFO1 via UBA domain interactions with ubiquitin for their subsequent degradation (PubMed:17144915, PubMed:16478980).  Required for S-phase checkpoint control (PubMed:11238935, PubMed:17144915).
What are the official names of this protein?
DNA damage-inducible protein 1, v-SNARE-master 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARGB_RENSM
Sequence: MSPLTSATSAPNKAEILIEALPWIQQFAGTVVVVKYGGNAMVSDELRQAFTEDMVFLHHVGIKPVVVHGGGPQINSMLGKLGIESEFKGGLRVTTPEAMEVVRMVLAGQVGRELVGLINAHGPYAVGLSGEDGALLQAVRTGTVVDGVEVDLGQVGEVIGVNPGSILDLLDAGRIPVISTIAPEVGKASSVLNVNADTAAAALAVALQASRLVILTDVEGLYRNWPDKDSLISALSVKELRELLPSLASGMIPKMTACLKAVDGGVRRASVVDGRSPHSMLLEIFTTAGNGTQVFPEAGPQGEKA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMT1_YEAS8
Sequence: MSELKTGHAGHNPWASVANSGPISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLIILRILGYAKFRSLNKTDAKNWFPISFLLVLMIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQAVAAKAASLAEGAAGAVASFNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQPLRK
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.  Defective copy causes severe glycosylation defect and abnormal retention of soluble endoplasmic reticulum proteins.  Involved in vanadate sensitivity (By similarity).
What are the official names of this protein?
GDP-mannose transporter 1, GMT 1, Low dye-binding protein 3, Morphogenesis checkpoint-dependent protein 3, Vanadate resistance glycosylation protein 4.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Recycles between the Golgi apparatus and the endoplasmic reticulum.
Protein: HSSR_STAEQ
Sequence: MINCLIVDDDKKLLQYVSSHLERESIQTHTFTSGEASLDFLENKNVDIAIVDIMMSGMDGFELCQTLKDDYHIPVIMLTARDALSDKERAFLSGTDDYVTKPFEVKELLFRIKAVLRRYQINADNELQLGNLILNQSYMEITVGSKTMNLPNKEFQLLFLLASNPKHIFTRDDIIEKIWGFDYEGDDRTVDVHIKRLRQRLSKLKSSVSIQTVRGQGYRVDQNV
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme response regulator HssR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_STAA1
Sequence: MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG1_LISIN
Sequence: MVKTWDEFLEQEAKQPYFIELMKAVSEAREEGNVYPSEEDMFSCFRLCPYDKVKVVILGQDPYHGPGQAHGLSFSVQKDVRIPPSLRNIYKELKSDLDIDPANHGYLAKWAEQGVLLMNTSWSVEEGKAGSHKKLGWATFTDHVLEELNNYDKPLVFILWGNHAIKAASGITNPKHLLIKGVHPSPLAASRGFFGSKPFSKTNEFLKENNRTPIDWDLNSK
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase 1, UDG 1.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IGF2_BOVIN
Sequence: MGITAGKSVLVLLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSRINRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSASTTVLPDDVTAYPVGKFFQYDIWKQSTQRLRRGLPAFLRARRGRTLAKELEALREAKSHRPLIALPTQDPATHGGASSKASSD
What is the function of this protein?
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion.  Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
What are the official names of this protein?
Insulin-like growth factor II, IGF-II, Erythrotropin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14_HAHCH
Sequence: MAKVGMRERELKREKTVAKYAEKRAALKAIIANPNVSDEERWEAQMKLQKLPRDASPSRLRNRCQVTGRPHAVLRKFRLSRIKLREAAMRGDVPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ASSY_ECO81
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTA_LAWIP
Sequence: MTGKGCIIELKNVSKIFEDTCALDNINLQIANGEFLTLLGPSGCGKTTILRIISGFETPDVGEILIAGVNVSGFPPERRQVNTVFQHYALFPHMTVRDNVAFGLRMQKCPREKVNELVFEALRMVHLENFADRRPSQLSGGQQQRVAIARAVVNKPLLLLLDEPFSALDHKLRQIMQLEIKHLQRKLGITFVFVTHDQEEAFAMSDRVVVMNQGRIEQIGTPQCIYEEPVNLFVARFVGEINNLAGTILSCNDEGIYEAAIANEVFPLRTPHRFSPGEAVNVLLRPEDIRIYLLDEEVLKVPHLRGRIEETVYKGATVDIIIALDVGGTLRVAEFFNEDDAEISYNEGERVAVTWVDGWEVVLPHEMA
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RM53_BOVIN
Sequence: MAAALARLGLRSVKQVRVQFCPFEKNVESTRTFLQAVSSEKVRSTNLNCSVIADVRHDGSEPCVDVLFGDGHRLIMRGAHLTAQEMLSAFASHIQARGAAASGDKPSASTGR
What are the official names of this protein?
39S ribosomal protein L53, mitochondrial, L53mt, MRP-L53.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL53 family.
Protein: NPD_STAA8
Sequence: MKHDLETLKHIIDSSNRITFFTGAGVSVASGVPDFRSMGGLFDEISKDGLSPEYLLSRDYLEDDPEGFINFCHKRLLFVDTMPNIVHDWIAKLERNQQSLGVITQNIDGLHSDAGSQHVDELHGTLNRFYCNVCHKSYTKSDVIDRTLKHCDNCGGAIRPDIVLYGEMLDQPTIIRALNKIEHADTLVVLGSSLVVQPAAGLISHFKGDNLIIINKDRTPYDSDATLVIHDDMVSVVKSLMTE
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_MARN8
Sequence: MSRSLHDQTLALAGLCQAATLVQQIAHNGNCNEDSLETCIRSLFATNPASTLDVYGGELSDIREGLTVLSTVLAQHGQPQDVEILRYMFNLIQLEAKLKRSPDMLDVIGNRIEQARHTASHFGYSHSNLLGNLASIYADTISTFRLRIQVTGNPQILQRNENADKVRALLLAGIRSAVLWRQSGGHRWQLIFTRKKVISHARELLR
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARLY_MYCSS
Sequence: MSTNEGSLWGGRFADGPADALAALSKSTHFDWVLAPYDIAASKAHARVLFSAGLLTEDQRDGLLAGLDSLASDVADGSFAPLVTDEDVHGALERGLIDRVGAELGGRLRAGRSRNDQVATLFRAWLRDAIRRVADGVLGVVSALATQAAAHPTAIMPGKTHLQSAQPVLLAHHLLAHAHPLLRDVDRLADFDKRAAVSPYGAGALAGSSLGLDPDAIAAELGFDSAADNSIDATAARDFAAEAAFVLAMIGVDLSRLAEDIILWSTTEFGYVTLHDAWSTGSSIMPQKKNPDIAELARGKSGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAVAGLVSTLSFDVDRMAELAPLGYTLATDVAEWLVRRGVPFRVAHEAAGAAVRAAEARGVGLEDLEDAELTGIHPELTGDVREVLTIEGSVNSRDARGGTAPVQVAKQLNVVRDTADRLRLRLRT
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_LACDA
Sequence: MKHRKGRVEGEILRELTKIIRKNIRDPRVSNVTFTAVECSNDFSYATVYYSLLTEDEQAQKEAEAGLEKAKGTMRHLLGQSLTMYKVPELIFKRDQSVIYGSKIDRLLADLKKQEQDRQN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_ACIB5
Sequence: MSQTLQAAYAAKRKARRFAVQGIYEWQMSHNPVHEIEARTRAENAMHKVDLNYYHELLTQVIAQHEDLDALLIPVLDREIDALDGVELATLRLGAYELRDHLEIPYRVVLDEAIELAKHFGGADSHKYINGVLDRLSSTLRSAEKQQAK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: DPOLQ_CAEEL
Sequence: MDEASCRFPEWVSSKIIDYYAEQNIKALFDWQIDVLNEARQFEDQHLIFSAPTSAGKSIVAELLSWKVASTGRKVLFVLPYISVAREKLHQIQRCWRRDDISVCGFIGPQASNPNEWLGAVCTIEKAASLTNRALSEDWFEEIGMIVVDEMHMVFDSSRGAHIEHMLSKVLLWNQSALEKVRIIGMSATIPELYRIGKWLDGAKVFEARFRPIVLQNHIVIGSELRKSGDNKVLREFSEDPLILLTEESFRRNSQTLVMISSKLDAEKTALNIASRFHEINKTDSSLLEILKERANGLLFIKHGLERNGCKDRNVMSTLAWGVAYHHAGLTMEERECIELGFREKNIVILVATSTLASGVNLPAERVLIKAQPRGPSALTSLNYRQMVGRAGRTGHATRGETYLLIKKCDRDAVLKIIETPIDQGVLTRKRDAERTNLSRFILEGICTGLTTTRSQIHDLCKLLLFNSENLQLSDIAIEMLLRNSFISQDENDDQLSPTQLGRAAIASSLPPEASLAIFEDLNSASRAIALDTELHMLYLVYFYKNSRAQIIQKIFKIYSIFILKKFKNLEPKFKKKISENITVHITNSIRKKQHFWHVTPINVSVWQECDWHHLFSIFSKLPSDHKRIAKLVGVSEKFILDQLQGRRNDKLLQIHIRFFSALALFDLISEMSIYEVSHKYRIPRGCLQTLQSQSATYAAMIVAFCLRLGWTYLKALLDGFATRLLFGVRSELSELVAIEGIDGQRARILHERGVTCLSHLSACDSSKLAHFLTLAVPYSSSNSNDGLGEWLFGEPRMRVDVAARTLKERARKVLIRRVQELGISVELPKFEENEENIQESCDSGLPDSCEGMEDELEEKENIVKMEEMTKSVTEMSLTDNTISFKSEDDLFKKEIKVEEDEVFIKKEIDEDEEEIVEETVIECLETSLLKLKASTDEVFLRRLSQTFSPIGRSRSILNNSLLEDSFDRPVPRSSIPILNFITPKRESPTPYFEDSFDRPIPGSLPISSSRRKSVLTNIANLDSSRRESINSNASDNNSFDVFVTPPTKSAKEEKRRIAVKHPRVGNIIYSPLTSSPVIKHPKLEINHFYLKDVCHDHNAWNLWTKSSTSTSSCSIRVSDDYTGIAIRTDAGNTFIPLLETFGGEPSPASKYFESFSKCIIPLNTRLEFLKTLAVTVEMYISSMEDAFLIFEKFGIKIFRLKVVRIAAYLNNVIDVEQEENSNFLPILMDRYSILDPEIRKTCSSSLHKAAVEVYSLKPIFEKMCCSGASLQLEMESCQTVLNIFYSGIVFDQALCNSFIYKIRKQIENLEENIWRLAYGKFNIHSSNEVANVLFYRLGLIYPETSGCKPKLRHLPTNKLILEQMNTQHPIVGKILEYRQIQHTLTQCLMPLAKFIGRIHCWFEMCTSTGRILTSVPNLQNVPKRISSDGMSARQLFIANSENLLIGADYKQLELRVLAHLSNDSNLVNLITSDRDLFEELSIQWNFPRDAVKQLCYGLIYGMGAKSLSELTRMSIEDAEKMLKAFFAMFPGVRSYINETKEKVCKEEPISTIIGRRTIIKASGIGEERARIERVAVNYTIQGSASEIFKTAIVDIESKIKEFGAQIVLTIHDEVLVECPEIHVAAASESIENCMQNALSHLLRVPMRVSMKTGRSWADLK
What is the function of this protein?
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA.  MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions (PubMed:24614976).  Required to prevent extensive loss of sequences near G-quadruplex (G4) DNA sites, which are prone to cause genome alterations, by generating deletions (PubMed:24496117).
What are the official names of this protein?
DNA polymerase theta.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ELP6_RAT
Sequence: MFPELNNLLSITPDRTEQGKLTLLCDAKTDGSFLVHHFLSFYLKANCKVCFVALVQSFSHYNIVGQKLGVSLTAARERGQLVFLEGLKSSVEVLFHSQEEPHPLQFLREAGAGNLQSLYTFIQDTLKPADSGESPWKCPVLLVDNLSVLLSLGVGAVAVLDFMQYCRATVCCELKGNVVALVHDTEGAEDEENNILLNGLSHQSHLILRTQGLATGFCKDVHGQLSILWRRSSQPTAQRARSLTYQYKIQDKNVSFFAKGMSRAVL
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity).  The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).  Involved in cell migration (By similarity).
What are the official names of this protein?
Elongator complex protein 6.
What is the protein family that this protein belongs to?
Belongs to the ELP6 family.
Protein: C515A_DICDI
Sequence: MILGIILGLFIYIYLINIKFFNRAVPSSLLVGENKLKCKFPSGPLILPIIGSLYKLSLKYPHLSFKQLSDKYGKVFSLKMGSIDTIVINDINFLQKSFRDNPTFFSQRFHLPSFYYMGKYQGIIFGNGSHWRKLKDILSSSITKSKSRQMEELFYNEYFKAEEYLLKKINQDNNIDMGPIFKRILLNILYRFLFGVSFEYDDNLLSKEFYSFIQSYNKLFEYLAKQPADFIPILKPFNNYKEIEKEYNNCLNFFQPLIDNILKNISDDDDDGNEPKCFLEYFISEIRKDTSNLIKITDLPYICFDIIVAGIVTTSTTMDWMLLYLTNYPNIQEKLFFEINTPNHPLHKDKLQFPYLNSIIKETLRISPPAPFALPHICTDDIVIDDIFIPKNTQVIPNIYGCNRSNIESSESNVFNPDHFLSKDELNIGQCAFSFGSRQCPGANVADSIMFLVSTKLYKTFKFERTTTQLNDENGHFTRSLSPFEFKSKLIIRK
What are the official names of this protein?
Probable cytochrome P450 515A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AB1IP_CHICK
Sequence: MEQTCDDIDEMFSNLLGEMDMLTQSLGVETVQTPSPKVTNEEFSFTVGFKDLNESLNALEDKDLDALMADLVADINEVEQRTLQAQKTSGNQQSVVTQPSTGTNNDFCSKLSPCATITGQFKNDLPPPPPAPDLDLPPPPPPPPPEPLSQEEQEARAKADKIKLALEKLKEAKIKKLVVKVHMYDNSTKSLMVDERQVTRDVLDNLFEKTHCDCSVDWCLYEVYPELQIERFFEDHENVVEVLSDWTRDSENKVLFLEKKEKYALFKNPQNFYLANKGKNESKEMNDKSKEALLEESFCGASVIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLMCFIQFENMNVYYGSQHKVKYKAPTDHCFVLKHPQIQKESQYIKYLCCDDRATLHQWVTGIRIAKYGKTLYDNYKCAVKKAGLSSQWANQGTLEPAAPTGSLSAGAVQANGQIPRVVLPSSAEVAETQKKVDPAIRA
What is the function of this protein?
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling.
What are the official names of this protein?
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, APBB1-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the MRL family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Protein: AAS_ECOL6
Sequence: MLFSFFRNLCRVLYRVRVTGDTKALKGERVLITPNHVSFIDGILLALFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVEMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQLKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYA_KINRD
Sequence: MQTAEIRRRWLDFFERKEHTVVPSASLVSSDPSLMFTVAGMVPFIPYLTAQVPAPYKRATSVQKCLRTLDIDEVGKTTRHGTFFQMNGNFSFGDYFKREAVAFAWELLTTPEADGGLGFDPERLWTTVYLDDDEAFQLWREVGMPAERIQRRGKADNYWNTGQPGPGGPCSEIYFDRGPAYGAEGGPEADEDRYIEIWNLVFMQYQLSAVRTKVDFDVEGELPAKNIDTGMGLERVAFLKQGVDNMYEIDEVRPVLDKAAELSGRRYGAVHEDDVRMRVVADHVRSALMLIGDGVTPGNEGAGYVLRRLVRRAVRAMRLLGVEEPALPHLLPASMEVMSASYPQLRSDFERISAVAYAEEDAFRRTLVSGTAIFETAVAQTKAAGGSSLSGERAFALHDTYGFPIDLTLEMAAEAGVGVDEPGFRALMAEQVGRAKADAKAKKTGGVDLAIYRSTLEQLPAPVVFTGYEAAAGEARISVVLQGGVSTPSAPAGTDVEVVLDRTPFYAEGGGQLADHGTVTTTSGAVLAVSDVQQPVRGLYVHKGTVTSGELVAGDAVHAVVDAGRRRSISRAHTATHLVHQVVREHLGDTATQAGSQNAPGRMRFDYRSTAQVAGDVVRDIEAVVNERIHDDLEVSAAVMDRESALNSGAMALFGEKYGEKVRVVSIGEDWSKELCGGTHTLTSQQVGLVSIVSESSIGSGARRIEALVGADAFDFLTREHLLVNQLTEVVKARPEELPDRIGALLTRLGDAEKEIARLRGGQVLALAPTIAAKPVDKFGVRVVTHDAGPVSADDLRTLVLDVRSRLGEERPSVVAVAGVAKDRPVVVVATNAEARRWGVKAGELVRTAAKTLGGGGGGKDDLAQGGGQDPSKVPAALQGIEDFVGARVTGSV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_STACT
Sequence: MSGIIEAKKQLVEQIADQLKNSVSTVIVNYRGLTVAEVTELRKQLREAGVEYKVYKNTMMRRAAEQAGLEGLDEFLTGPTAVATSTEDVVAPAKVIAGFAKEHEALEIKTGVMDGSIISAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAVGESKEESAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.