PharMolix/UniProtQA huggingface dataset:
Protein: PROA_BORA1
Sequence: MSSIEQIMLTLGENARQASRAMMRASGTAKNRALLAMAELIIDGKAALQAANALDLEAARANGLEPALLDRLTLSDRSVQLMAEGLRQIAALPDPVGSLGPTQVRPNGMRVAQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALHSNLALGAIVQAGLAAAELPPAAVQVVSTTDRAAVGKLVTMTEHIDVIVPRGGKGLIARLAQEARVPLIKHLDGNCHVYIDAAADPDRALEIAFNAKTYRYGVCGSMETLLVHRAIAPTQLPRIARALIEHGVELRGCERSQAIVPGMAAASEEDWGTEYLGPVLAVRVVDDLDQAMEHIARWGSGHTDAIVTENLAAAQRFQREVDSSSVYVNLPTVFADGFEYGLGAEIGISTNRLHARGPVGLEGLTTYKWVLTGEGQTRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMP06_NAUMA
Sequence: ADLFLR
What are the official names of this protein?
Uncharacterized protein SMPP6.
Protein: KISHB_XENLA
Sequence: MTNVYSLDGLLVFALLFVCTCAYFRKVPRLRSWLLSEKKGVWGVFYKAAVIGSRLHLAVSISCIAMAFYVLFIK
What is the function of this protein?
Involved in the early part of the secretory pathway.
What are the official names of this protein?
Protein kish-B, Transmembrane protein 167B.
What is the protein family that this protein belongs to?
Belongs to the KISH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein.
Protein: GUAA_SALTY
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRALQYVFEAGVPVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEERFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NTPPA_HYDCU
Sequence: MKRRLYLSSSSPRRKELLDQAGIPFDLVNAPVEETGLPNESPESFVLRMAVEKALSGFNKVPGKNVWVLGSDTIILKDGKVFGKPKHKMDAYRMLMSFSGEEHTVMTSIAIVNDGAVYSDVCQTNVFFRPISDSEFEQYWATGEAEDKAGAYGIQGQAAKFIEKIEGSYSAVMGLPLYELDKLLRESNFYSE
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDHM_RAT
Sequence: MLSALARPVGAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVIECSFVQSKETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKNMK
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: XPT_DEIDV
Sequence: MRALVDAIRAQGTVLPGGILKVDGLINHQLLPQLTREMGETFARSFGPLKPTKVVTIEVSGIAPALATSMVLGVPMVYARKKRPVTMQGPVYTAQSVSRTKGGVVELFVSHEYLSADDRVVVIDDFLASGGTLLALAGMIRESGAQLLGMGCVVEKAFENGRANLASLGVPVRTLANIVRMDEGGTLVVEAGH
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOPW_BACSU
Sequence: MELSLDELKLCLKPLVFFGELKLEISDYEEGKKIEVLDHDEGSLINLADQTINENYVCTTCNCTLYTNENNEVCFIEHPYGAITAVNKDQVIHLTKLIGAIINTDEEDPVE
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YopW.
Protein: VPC12_MYCTO
Sequence: MIVLDASAAVELMLTTPAGAAVARRLRGETVHAPAHFDVEVIGAIRQAVVRQLISDHEGLVVVVNFLSLPVRRWPLKPFTQRAYQLRSTHTVADGAYVALAEGLGVPLITCDGRLAQSHGHNAEIELVA
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  The cognate antitoxin is VapB12 (By similarity).
What are the official names of this protein?
Ribonuclease VapC12, RNase VapC12, Toxin VapC12.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: TMIG1_HUMAN
Sequence: MAWKSSVIMQMGRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAACVVIFLTLCFGLIARRKKIMKLCMKDKDPHSETAL
What is the function of this protein?
May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival.
What are the official names of this protein?
Transmembrane and immunoglobulin domain-containing protein 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: YCFP_SHIF8
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: QOX2_ACEAC
Sequence: MKNKLLARVARLGGLSSALLLAGCELDVLDPKGPVGEGVKTLIATSTVAMLIVVIPTILETLLFAWQYRQSNTSAEYLPKWCHSNKIEVTIWGVPSLIILFLAVITYQTCHSLDPYKPLEAEANTKPLHVEVVALDWKWLFIYPEQGIATVNQLAIPVNTPIDFNITSDSVMNSFFIPRLGSMIYAMAGMQTQLHLLASEPGDYLGESANYSGRGFSDMKFHTLAVSGDEFNAWVEKVKSSSEQLDSQTYPKLAAPSENPVEYFAHVEPGMFNTIVAKYNNGMVMDKSTGKMIQVQQSAMSDMNMKE
What are the official names of this protein?
Ubiquinol oxidase subunit 2, Cytochrome A1 subunit 2, Oxidase BA(3) subunit 2, Ubiquinol oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTL26_HUMAN
Sequence: MLVAAAAERNKDPILHVLRQYLDPAQRGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTNVKAPLHLDVTWGWEHWGGILPQSLDLLLCINMAHVSPLRCTEGLFRAAGHLLKPRALLITYGPYAINGKISPQSNVDFDLMLRCRNPEWGLRDTALLEDLGKASGLLLERMVDMPANNKCLIFRKN
What are the official names of this protein?
Methyltransferase-like 26.
What is the protein family that this protein belongs to?
Belongs to the UPF0585 family.
Protein: GCS2_PARDP
Sequence: MTEEPEFSLGVEEEYLLVDAETGDLREAPDALMEACKAELADQVGPEFLRCQIEIGTPVAADVAQARDHLARLRGSIARHAAEFGLAPISVACHPVADWRAQGRTDKDRYNQISQEMGGVARRMLICGMHVHVGISDKDMRIDLMNQFSWFLPHLLALSASSPFWLGEDTLLASYRTTVFAGYPRTGLPPRLGSWAEFDRSVEMLTETGIIQDASKIWWDLRPSARFPTLETRVCDACPRLDDAITLVALVQATLRMLWRLSRQNLRWRQYDNFLLGENRWRATRYGSTEGLIDFGSRRILPFDEIAESWLAAIAEDADALDSQPAVAGLRDMIARGSAAERQRALFASAITAGATPQEAFRSIVGWLIDEFRRDL
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: Y432_BUCBP
Sequence: MRKNKLEKMLKFPCLFTYKVIGLAQPELVDKIVKIIQCKLPGDYVPQIKSSNKGNYLSISITICANTFEEIESLYYELSNINIVRMVL
What are the official names of this protein?
UPF0250 protein bbp_432.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: PFKA1_BACTN
Sequence: MDNKYIGILTSGGDASGMNAAIRAVTRAAIFNGFKVKGIYRGYEGLIAGEVKELTTEDVSSIIQRGGTILKTARSETFTTPEGRKKAYKVIQKENINALIIIGGDGSLTGARIFAEEYDVTCIGLPGTIDNDLYGTDFTIGYDTALNTIVECVDKIRDTATSHDRIFFVEVMGRDAGFLAQNSAIASGAEAAIIPEDRTDVDQLETFIGRGFRKTKNSSIVIVTESPENKNGGAIYYADRVKKEYPGYDVRVSILGHLQRGGAPSANDRILASRLGEAAIQALMEGQRNVMIGIRNNEIVYVPFVQAIKKDKPIDKSLIRVLNELSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase 1, ATP-PFK 1, Phosphofructokinase 1, Phosphohexokinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_CLOP1
Sequence: MIDKDKIREGMKLILEAIGEDINREGLIETPDRIARMYEEIFSGIGMNAKEHLSKTFEVHSNDLVLEKDITFYSMCEHHLVPFYGKVHIAYIPNGRVVGLSKLARCVEVYSKKPQLQERLTTEIADSIMEYLDAQGVMVVVEGEHMCMTMRGVRKPGAKTVTTTYRGKFLEDESLKNDVFRMISM
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ISCU_ECOLI
Sequence: MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQIKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPVKIHCSILAEDAIKAAIADYKSKREAK
What is the function of this protein?
A scaffold on which IscS assembles Fe-S clusters.  Exists as 2 interconverting forms, a structured (S) and disordered (D) form.  The D-state is the preferred substrate for IscS.  Converts to the S-state when an Fe-S cluster is assembled, which helps it dissociate from IscS to transfer the Fe-S to an acceptor.  It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
What are the official names of this protein?
Iron-sulfur cluster assembly scaffold protein IscU, Sulfur acceptor protein IscU.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: APCD1_PELSI
Sequence: MSLPCCGRVRYLLLALLLHGLGEGSALLHPDSRSHPRSLEKSAWRAFKESQCHHMLKHLHNGARITVQMPPSIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYYGGNRCTNPTYTLVIRGKIRLRQASWIIRGGTEADYQLHNVQIISHSEAVAEKLSQLVNRTCPGFVPGNSPWEQDVSYNLWREENGCECTRALNFAMHELQLIRVEKQYLHHNLDHLVEELFLGDIHTDATQRMYYRPSSYQPPLQNAKNHDHSCIACRIIYRSDEHHPPILPPKADLTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPICKHPTFTIYAKGRYSRGVHSSKVMGGTEFVFKVNHMKVTPMDIATASLLNVFNGNECGAEGSWQVGVQQDVTHTNGCVALGIRLPHTEYEIFKMEQNARGSYLLYNGQRPSDGSSPDRPEKRATSYQMPLVQCASSAPRPEESAEENKIGRYSSRAPKKDSSVFMLTLMLFICTGSHWNIHS
What is the function of this protein?
Negative regulator of the Wnt signaling pathway.  Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin (By similarity).
What are the official names of this protein?
Protein APCDD1, Adenomatosis polyposis coli down-regulated 1 protein homolog, PsAPCDD1.
What is the protein family that this protein belongs to?
Belongs to the APCDD1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CHS2_EXODE
Sequence: MAYNRLGSPQRDGPYSPSAQPQYDSRSPSPGRPLQPYIHPDEAYARQQPLHLQMPTASDDRLAMQPTYSVENVHNPQAYGQQYGQHLPDSGDMGYGRNDYIVSPEEHHDAYYTQPYSPHPQGDYALDPYPSHDEPYRPDTDNVPILQPDSAYGPDPHTQPGMDYDDYQEEPRPTPSPAPIRRWKTVKEVQLFNGNLVLDCPVPPKLLANVPHAKPPERDEFTHMRYSAATCDPSDFHNERFTLRQRLFAKPRQTELFIVVTMYNEDEFLFARTMIGVFKNIEFMCNRSSSKTWGKEAWKKIVVCIVSDGRAKINPRTRAVLAGLGVYQDGIAKQQVNGKDVTAHIYEYTTQVGLELKGTQVSLKPRSATPVQLLFCLKEKNQKKINSHRWFFQAFGRVLDPNICVLIDAGTKPGKDSIYQLWKAFDLEPMCGGACGEIKVMLDHGKKLLNPLVATQNFEYKMSNILDKPLESAFGFISVLPGAFCAYRYVALQNDKNGVGPLEKYFKGETMHADAGVFTANMYLAEDRILCFELVSKRNCRWILQYVKSATGETDVPDRIPEFVLQRRRWLNGSFFAAVYAVAHVYQLWRTDHSFLRKLMFLIEFTYQTINMLFAWFAIGNFFLVFRLLTASLGTKETLGTAGTVLGVVFEFVYLGTLLYCFILSMGNRPQGNPKSYMMMVIFWSVLMVWLTFASIFLTVKSIETEVQQKDFSFSTIFNNSTFFGLIVSLASTYVLWFVASFLFFDPWHMFTCFLQYIVLTPTYINVLNIYAFCNTHDITWGTKGDDKAEKLPSANVKPGGKVDVLIPQDDGDLNAQYDSELKKFATKPPKEVKAPNPADKQEDYYKSFRSNVVTAWMITNFILVAAVLNIAGFDRINVHDTQQQNSTIYLAVILWSVAGLSLFRFTGACWFLVVRMVSLEIWSVCKV
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 2, Chitin-UDP acetyl-glucosaminyl transferase 2, Class-I chitin synthase 2.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class I subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSA_MYCS2
Sequence: MSFPYFISPEQAMRERSELARKGIARGRSVVALAYSEGVLFVAENPSRSLQKVSELYDRVGFAAVGRFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADEPHFVVMGGTTEPIIAALNESYTENASLQDAVEIAVKALSASAEGAEPRSLGPSTLEVAILDAGRPRRAFRRITGAALEALLPEQPQQADSGDKPTE
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.  The M. smegmatis proteasome is able to cleave oligopeptides after hydrophobic residues, thus displaying chymotrypsin-like activity.  In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin-like protein (Pup).  Identified substrates of the M. smegmatis proteasome are the pupylated SodA and Ino1 proteins (PubMed:19028679).  The Pup-proteasome system (PPS) is essential for survival under starvation; PPS likely functions to recycle amino acids under nitrogen starvation, thereby enabling the cell to maintain basal metabolic activities (PubMed:24986881).
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNX_PSEE4
Sequence: MNYSNPTQLQAAILDWAGTVVDFGSFAPTQIFVEAFAEFDVQVSIEEARGPMGMGKWDHIRTLCDVPEIAERYRKVFGRTPTDDDVTAIYERFMPLQIEKIAVHSALIPGALDTLTGLRKEGLKIGSCSGYPKVVMDKVVELAAQNGYVADHVVATDETPNGRPWPAQALANVIALGIDDVAACVKVDDTVPGILEGRRAGMWTVALVCSGNALGLTWEGYRALSAEKLESERKRIHGMFAASRPHYLIDTINELPEVIADINRRLAKGEMPQAV
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: GCSPA_CHLPD
Sequence: MPFIVNTDQDTREMLSVLGAASFDELIPDIPEEIRLKKALDLFPAMSEQEVKRLLEGLASSNTSTSDYVSYLGGGAYDHFIPSAIKTIVSRSEFYTAYTPYQAEVSQGTLQAIYEYQSLMCRLYDMDVANASMYDGATALAEAVLMAISVTGRQEVIVAGKLHPHYCEVLKTYLEAGGHSAVVQNTLENGVGTLDGLGALLTDRCAAVIVQQPNFYGSLEDVEAIGELAHSKGALFVVSADPVSLGLLAAPGSYGADIAVGEGQPLGNAQSFGGPYLGIFTVKQDLVRKIPGRLVGMTKDRNGDDGFILTLQTREQHIRREKATSNICTNQALNALHAAIYLSLLGKQGIIDVAEQSALKSHYLAEQIADIPGFSLKYSAPFFREFVVETPMAAREVISNLLEKKIFAGCDLSVYDEAGLLVAVTEKRTKAELDAFVEYLGALK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: PDUL_LEVBA
Sequence: MDETALRALIQRIIKEELDPDRIPIGVSNHHIHLTEADFNTLFPNQKMTVLKPLKQPKEFASKQTVDIVGPKGTIKHVRVLGPCRAHSQVEIARSEALNIGVPAPIRLSGHLDGAPSVKLVTPDGEVTVQGVIIAKRHIHMSNEDAKRFGVKLGDTVSVEVQSQDRRTIYNDVICRPREDFVLEMHIDTDEANAANVDGNTFGKIVKA
What is the function of this protein?
Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
What are the official names of this protein?
Phosphate propanoyltransferase, Phosphate acyltransferase PduL, Phosphotransacylase PduL, PTAC, Propanediol utilization protein PduL.
What is the protein family that this protein belongs to?
Belongs to the PduL family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: RS6_ECOSM
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: BBSE_THAAR
Sequence: MGQDFSRFRVVDMTGELGPYTAKMFAGLGADVIHVESPAGDPLRRVGPWFRNQPGVQASLPYLYYNAGKRGFAVDLEHEAGREVFRTLCSGADLLVESCRPGYLDGLGLSYEELSRDNARLVQTSVTPFGRTGPLAAYPGSDLTCSALSGFLWLAGIDGDKPVRAPDNQAYRMAEAYAAVGSAIALFSAQRTGKGQLVDVACIEAEAMALENAAQFWDLEGKIRRGRGREAGSATLHPCADGYIALVAIMGRNKDMWTPFVRWMEAEGVEEWPLFDDDKWIDYAYRTSEEGYTTFCRVFERYTRSRSKAELYEIGQRFNVAVTPVSDGRDLLANPQLAHREFWQTQFNDTLGADITYPGAPYEFGELQWQLGRNAPRIGEHTREILVECGYPAFEIDNLLRMGAVYAEQH
What is the function of this protein?
Catalyzes the reversible conversion of (R)-2-benzylsuccinate to (R)-2-benzylsuccinyl-CoA.  Inactive with (S)-benzylsuccinate.
What are the official names of this protein?
Succinyl-CoA:(R)-benzylsuccinate CoA-transferase subunit BbsE.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: GLMM_CORJK
Sequence: MGKLFGTDGVRGLANKKLTAPLAMKLGAAAARVLVSKEEVGGRRPTAVVGRDPRVSGEMLTAALSAGMASQGVDVLDVGVIPTPAVAFLTDDFGADMGVMISASHNPMPDNGIKFFAAGGRKLQDDVEDEIEATMLELPETGPTGAAIGRILDESSDALERYLAHVGTAINHPLDGIRVVVDCANGAASTAAPEAYRQAGADVVAIHSRPNSFNINDGVGSTHIEVLQKAVLEHQADLGLAHDGDADRCLAVDSEGNVVDGDQIMAILAVAMKENGELKQNTLVATVMSNLGMKLAMRANGIKVLETQVGDRYVLAELLASDLSLGGEQSGHVIISEHATTGDGTLTGLTLMARMAQTGKPLSELASVMTVLPQTLINVPVADKSVIADDERVVEAIAKAEEDLGDAGRVLLRPSGTEELFRVMVEAADPGTARRIAGKLAAVVAEV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: YEJL_ECO45
Sequence: MPQISRYSDEQVEQLLAELLNILEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINEDKAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: GLYA_ACIF2
Sequence: MFSKTLTIADFDPVLWDAMRKEARRQEDHVELIASENYASPMVMAAQGSVLTNKYAEGYPGKRYYGGCEYVDIAEQLAMDRALELFGAEHANVQAHSGSQANQAVYLSVLQPGDKIMGMSLAHGGHLTHGAKVNVSGKLFQVAAYGVRAEDGRIDYDAMAEQAERERPKMIVAGASAYSRVIDFARIGEIARSIGAYLLVDMAHIAGLVATGLHPSPVPHADFVTTTTHKTLRGPRGGLILCREQYAKKVNSLIFPGLQGGPLMHVIAAKAVAFREALQPEFKSYQQQVIHNAQTLSKVLAGRGYGAVSGGTDNHLFLLNLGEKVTGKEAEEALGQANITVNKNAVPFDIRPPAVTSGIRIGTPAATTRGFGEAEMHRLGNGIADVLDASSDAAVIERVRADMKALCHQFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_BRUO2
Sequence: MSVDISTVKRVAHLARIAVSEDDAERMTGELNAILGFVEQLNEVDVEGIEPMTSVTPMKMRMREDKVTDGGIAAAVVANAPVTEDNFFVVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RS11_METCA
Sequence: MATTGRPVKRVKRDISDGIAHISASFNNTIITITDRKGNALSWASAGASGFRGSRKSTPFAAQVAAEKAGAVAKEYGIKNLDVHVTGPGPGRESAVRSLNALGFKIVNVVDTTPLPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CLCC1_XENLA
Sequence: MRLFLLVALYLSPVYGDYTDEWIDPSDMLNYDAASGKMKNKPQVESTQSYYSVENTVSQDATQQPAQKANELHQNPDMTCSAEYQEYKTKLENLKGQLEETKRMEKSKSKSQAIFKRYLNKILIEAGRIGLPDESYPKAHYDAEVVFTMEMLQEIQSFLNNGDWNVGALDDALSSTLVQFKHHNEEEWKWKFEDSFGVDVYTLFMLILCVLCLVKLIATEIWTHIGWFTQLKRLLILSTVISFGWNWMYLYKVAFAERQAELAKLQDFDKCSQKISWSESLFDWMKGAATFQNDPCEDYFKALIVSPTLMVPPTKALALTFTNFITEPLKHIGKGIGEFLNALLSEIPLFFQVPVLIFIAVLLLAFFYGAGTAVMNPVNLYRRLTGPEREKPLPVEPTRSNRKRFIEDVRVPPALGQLPRDNDVVNIPKQQPLDDIDGSNNPPVTAPADPSDTGQVKSNNTGEPLVQEDHSIKKSIKESRNDERPNTESPEAKPQRPEEPVVETLRST
What is the function of this protein?
Seems to act as a chloride ion channel (By similarity).  Plays a role in retina development (By similarity).
What are the official names of this protein?
Chloride channel CLIC-like protein 1, Mid-1-related chloride channel protein 1, MCLC.
What is the protein family that this protein belongs to?
Belongs to the chloride channel MCLC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes.
Protein: RGMC_MOUSE
Sequence: MGQSPSPRSPHGSPPTLSTLTLLLLLCGQAHSQCKILRCNAEYVSSTLSLRGGGSPDTPRGGGRGGLASGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPARGPALPGAGPAPLTPDPCDYEARFSRLHGRAPGFLHCASFGDPHVRSFHNQFHTCRVQGAWPLLDNDFLFVQATSSPVSSGANATTIRKITIIFKNMQECIDQKVYQAEVDNLPAAFEDGSINGGDRPGGSSLSIQTANLGSHVEIRAAYIGTTIIIRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFDVSVSGDPNFTVAAQTALDDARIFLTDLENLHLFPSDAGPPLSPAICLVPLLSALFVLWLCFSK
What is the function of this protein?
Acts as a bone morphogenetic protein (BMP) coreceptor.  Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.
What are the official names of this protein?
Hemojuvelin, Hemochromatosis type 2 protein homolog, Hemojuvelin BMP coreceptor, RGM domain family member C.
What is the protein family that this protein belongs to?
Belongs to the repulsive guidance molecule (RGM) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Note=Also released in the extracellular space.