PharMolix/UniProtQA huggingface dataset:
Protein: TRUB_SHESM
Sequence: MARRSKGRFIDGIVLLDKATGMSSNFALQRVKRFFNANKAGHTGALDPLATGMLPICLGEATKFSQHLLDSDKRYLVTAKLGQRTDTSDSDGEVVQTRPIEFTEAQLMSALEHFRGDTLQVPSMYSALKYQGQPLYKYAREGIEVPREARPITVFELNFISLEGDELTLDIHCSKGTYIRTIIDDLGEMLGCGAHVIMLRRTQVAHYPYDKMVTLEQLEALVAKAQEEQLDPSSLLDSLLLPMDTAVADFPEVNVPDASAAYLMQGQAVRVSGLVADKLVRITLGTERRFVGIGEMNEDGLLAPKRLVVIHDQAKAS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: TIG_HAEIG
Sequence: MSLNIETTQGLERRVAITVPTEIVSKAIHEEFKRAAKNVRVDGFRKGHVPAHIIEQRFGASIRQDVLNDLLPRHFFDAVIAEKINIAGRPTFAIETFEEGKDLVFTATFEVYPEVKLQGLENIKVEKPTVEITEADIDKMIDVLRKQQATWAESQDIAKADDRVTIDFVGSVDGEEFEGGKATDFVLFMGQGRMIPGFEEGIVGHKAGEQFDIDVTFPAEYHAENLKGKAAKFAITLKKVENMVLPELTDEFVAKFGPNTKSVADLRAEIRKNMERELKNALVSRVKQQVINGLIEQNPIDVPASVVEEEINVLRNQAAQRFGGNTQQAAQLPRELFEAEATRRVQVGLLFSEVIKSNELKADKERAKAMIADIASAYEQPAEVVEYYSKNKELMNNIRNVVLEEQAVDAVLAKAQVTEKVSSFDEIMNPQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: 5057R_ASFB7
Sequence: MFSLQDLCRKNTFFLPNDFSKHTLQRLGLYWKEHGSVHRIEKDSIMIQNELVLSINDALQLAGEEGDTDVVQLLLLWEGNLHYAIIGALKTENYNLVCEYHSQIQDWHILLPLIQDPETFEKCHDLSLGCDLICLLQHAVKCDMLSILVKYKEDLLNVRIRHRTQSLFVLACENRRFEIIEWIGQNLSIPEPEAIFSIAIVTKDVELFSLGYKIIFDYMQRQGIFQLTNVVRMLLLNRHIGMAIEKGLLPFILETLKYGGSVKRALSYAVIDNKRKIIDYLVRHENIPRGTIERLLHLAVKKQSSRKTLNLLLSYINYKVKNVKKLLEHVVKYNSTLVIRILLEKKKNLLDATLTRYVKDSTYFQVKEFMQDFSISPEKFIKIAVREKRNVLIKGISEDIWENPAERIRNLKQIVCTIKYESGRQFLINIIHTIYQSYSLKPEEILKLATFYVKHNATTHFKDLCKYLWLNRGTESKKLFLECLEIADEKEFPDIKSIVSEYINYLFTAGAITKEEIMQVYALEYAMY
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.  Interferes with host NF-kappa-B promoter activity mediated by TLR8.  Mechanistically, inhibits the phosphorylation and subsequent nuclear translocation of host NF-kappa-B RELA subunit downstream of TLR8 (PubMed:34696476).  Promotes the expression of the autophagy-related protein host ULK1 to degrade host STING and inhibit the interferon response (PubMed:33712518).  Inhibits also JAK1- and JAK2-mediated signaling and thus negatively regulates the IFN-gamma signaling (PubMed:34517008, PubMed:34696476, PubMed:33712518).
What are the official names of this protein?
Protein MGF 505-7R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RL20_MARMM
Sequence: MSRVTSGPATAKRHKSVIKKAKGYYGRRKNTFRVAVQAVEKAGQYAYRDRRAKKRNFRALWIQRINAGARQHEMSYSVFMNGLTKAGIEVDRKVLADIAMHEPDAFKALVDQARAALG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MYC_BOVIN
Sequence: MPLNVSFANKNYDLDYDSVQPYFYCDEEENFYHQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVASFSPRGDDDGGGGSFSSADQLEMVTELLGGDMVNQSFICDPDDETLIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDGGSPSPARGHGGCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKPCASPDSTAFSPSSDSLLSSAESSPRASPEPLALHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQPPAKRSESGSPSAGSHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCASPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEQQKLKSEIDVLQKRREQLKLKLEQIRNSCA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: RL21_FRATM
Sequence: MYAIIKNGGKQYKVKEGEVVKLEKFDLGIGEKVEFDTVLMGQTAAGEVKIGAPTVAGAKVVGEVVEQGRHKKVKIMKFRRRKHSMKQQGHRQYFTAVKVSSISL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GPMI_SALRD
Sequence: MDSSKRHLLLILDGWGLADDPSVSAVEQADTPFVDHLYDEYPHGVLKASGLEVGLPDGQMGNSEVGHTNLGAGRVVYQEILRISKAIEDGSFFENDALVRAARHAKASDQKLHLMGCFSDGGVHSHLEHLYGLLELARREGLAPAQVNVHAFTDGRDTDPHGGVDYVEQFQKKADEIGVGRLASIVGRYYAMDRDERWARTERAYRLLTDGTGAAFDDPVTALKASYDDGVTDEFVEPRRIRADDADAFGDHGTRIEDGDAVVYYNFRSDRARQLTRAFTEADFDGFERERPDDLLFVTMSPYDDEFDLPVAFEKLNLEGTLGEVLSARGGRQLRAAETEKYAHVTYFFSGGREAPFDGEDRVLVPSPKVDTYDQQPEMSAPELADRVSRSLREADYTLAVLNFANPDMVGHTGDFEAAVAACEAVDRGARQVVEAARDQGYSVSIIADHGNADRLQNPDGSPHTAHTTALVPHIILKDGFEGPVRDGKLGDVAPTILTLLGEDVPDAMDGEVLVPAERAAAS
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: YUSN_BACSU
Sequence: MNQQNQKISNPQTPVPTTSEMNDRDFVNELLTTEKYMTTAYCTALHEFSHESLYQDIQSIFDESQKAQRKLYDLMFQYGWYSVEAEDSQKLQQSYQKFQQTIQQQSPYQQ
What are the official names of this protein?
Uncharacterized protein YusN.
Protein: YBEY_RHIE6
Sequence: MAELDIQISIENIGWPEEETLLAFCGRVLGAAAVYLRDSEKQPFPTMPPEVSLVFTDDASIQDINAEWRGKDKATNVLSFPAFPVQPGKMPGPMLGDIIIARETVEREAHELEKSFDDHLTHLLVHGFLHLLGYDHMNSAEAEIMEGLETRILAQLGLSDPYEGQDLKMEP
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_SPIOL
Sequence: MGGSSKTVRKLEVATPVPADIDIANAVEPLHIADIAADLNLSPRHYDLYGKYKAKVLLSVLDEVQETQDGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITASNNLLAAAIDTRMFHESTQSDKALFNRLCPPNKEGKRTFCNIMHRRLKKLGIDKTNPDDLTPEEVTKFARLDIDPDSITWRRVMDVNDRFLRKISVGQGPDEKGMVRETGFDISVASEIMAVLALTTSLADMRERLGKMVIGNSKAGEPITADDLGLGGALTVLMKDAINPTLMQTLEGTPVLVHAGPFANIAHGNSSIVADKIALKLVGPGGFVVTEAGFGSDIGTEKFMNIKCRYSGLTPQCAIVVATVRALKMHGGGPQVVAGKPLDRAYLTENVGLVEAGCVNLARHIINTKAYGSNVVVAINMFSSDTEAELNAVKKAAMDAGAFDAVICTHHAHGGKGAVDLGIAVQKACENVTQPLRFLYPLDISIKEKIEAIAKSYGAAGVEYSEQAEKKIEMYSKQGFSNLPICMAKTQYSFSHNAAEKGAPSGFILPIRDVRGSIGAGFIYPLVGTMSTMPGLPTRPCFFDIDLDTTTGKVIGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, 10-formyletrahydrofolate synthetase, FHS, FTHFS, Formyltetrahydrofolate synthetase.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: UBIE_WOLWR
Sequence: MSTIKIEKKSQLVKEVFDSVASRYDTMNDIMSLGMHRLWKDRMVNSVHFTKNSKVLDVAGGTGDIAIRIVRKEPSAKVTVCDINQNMLSRGRDKAINSNQINFDWVCANAESLPFEDSEFDYCTIAFGIRNVSDRKKALNEAHRVLKPHGKFICLEFAPMHYQNEIFTKLYDLYSFKVIPKIGSIVAKDKSSYEYLVKSIREFPTQADFKMEIEEVGFKNVEFHNMSYGIVALHIGTK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SNX8_MOUSE
Sequence: MTGRAMDPLPSPAVAAAAEAEADEEADPPATGPRTSQVTEWRALDPGRMQMPQGNPLLLSYTLQELLAKDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFHEVLLHKFPYRMVPALPPKRVLGADREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFMNCKLAARAKDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELSALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALLADRAAQQGKKEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAAHGREPESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLKPKLSCLFAGPHSVLTPPRSPQEDGVCPH
What is the function of this protein?
May be involved in several stages of intracellular trafficking.  May play a role in intracellular protein transport from early endosomes to the trans-Golgi network (By similarity).
What are the official names of this protein?
Sorting nexin-8.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with retromer components.
Protein: DNAA_STRPQ
Sequence: MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATIYLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQALNSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHLLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQSLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNITPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQIDTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLARQVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_STAAS
Sequence: MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHSFKPVGRALEEIADGKIRPVISSDYYGKE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PYRE_CLOPE
Sequence: MKNTDAMVIDTLKEVGALLEGHFLLSSGRHSNRYCQCAQLLKYPEKAEKVLKVVADQLKDIDFDLVVGPAMGGVIVAYELGRQLGKPAIFTERENGEMTLRRGFTIEKGQKVVITEDVVTTGKSFKEAAKVIEEQGGEVVAVVCIVDRTPGNVTDFPMYSSIKLDIESFEAENCPLCKEGVPYIKPGSRNIK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: MOBA_HELPJ
Sequence: MKNPIINNIPCVLLAGGKSSRFIINNIPINKALMPLKSYPSLLEYQYTRLLKLFKQVIISAKKSYELNAPYLLEKEGGLFSPLFGIHNAFLTLQTPYIFFIAIDTPLVSFESIKILCGIQNFSVVYAKSPTKEHYLISLWHQSILNALNYTLKTQNYRLSDLIKNASSTAIHFDKEEEFLNLNTLKDYELAVQILKEGSNGRRRKDRTP
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_METFK
Sequence: MYQVMLVALGGAIGSAARFTLSGLVLRYSLDWRFPLPTFTVNIIGCLVIGMLAGLASKEGFISPDMRVLLFTGLVGGFTTFSAFGLETLVLLREGLVGIAAAYIVSSIVVGLVLMWLGFELVKMTMQA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DHDH_MACFA
Sequence: MALRWGIVSVGLISSDFTAVLQTLPRSEHQVVAVAARDLSRAKEFAQKHDIPKAYGSYEELAKDPNVEVAYVGTQHPQHKAAVMLCLAAGKAVLCEKPMGVNAAEVREMVTEARSRGLFLMEAIWTRFFPASEALRSVLAQGTLGDLRVARAEFGKNLTHVPRAVDWAQAGGALLDLGIYCVQFISMVFGGQKPEKISVMGRRHETGVDDTVTVLLQYPGEVHGSFTCSITAQLSNTASVSGTKGMAQLLNPCWCPTELVVKGEHKEFLLPPVPKNCNFDNGAGMSYEAKHVRECLRKGLKESPVIPLVESELLADILEEVRRAIGVTFPQDKH
What are the official names of this protein?
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, Cmo2DD, D-xylose 1-dehydrogenase, D-xylose-NADP dehydrogenase, Dimeric dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: MCP5_SCHPO
Sequence: MEKKQDNEVELYSIDLKNRNESAKIKLAYAKALEESILCETRKIEQEIKDQVVQKENKTYFNNKFDNRYKLRDLEKNLAEEEVRITEMLTIQRQDIAIERRKNTNCFSESSQVDQYSVTETNLQYATNIGLNLLQQLRYLRLQLSEKEDLHKKLSVDNAHLIKQLDLLSSNMKTLMKEKTKVQGQRDLLEQRLQGLMKKLTEVESLTVSLNDEKNKLTLELTNLRICLHELQLNAEKGETIDESEDSKNTLVTEDENDDSVFLESSSDKYFDSSSFDAEQEEKHDFPIDPFLSLESNVQTSVSQSSAVLKSINLAKQELVSVNHLVADDTKTPSPNLSSEIIENTKADIKKSIRSLNKAVSPENSIDIEDETDRDDEFICFLLSYQQLQKALKSNLGLFQLSCLYPLSLNHLIQSFFQSLTSQISIKDIDSKNKQVIKLFKPTKSSDRQEIFELAQFEPRQKFPIDTNSSKCDMSASTEMHLKDTEKFANFKLKENILNHSSIYERDVSYLPALNKGGRENYLNNRVSSYRLVKPILNSYGNHVLNRIQHDILENHFCCLKNVKDFVCGANTISMQWNLQKNMEFISSVFSLIKNEVNDTSANSVILRTDALSNVATTRLKRKLTSAIIDCSIPRRRLRHYSNPEIAEFKNFRLSTDISHSNVRNSKKLCSNGSMNCMRQGKAVFPRKIPYQEHDWEQWEKIAQSSMFKNRSIASRQSLETSDVTLDINMSSRHSNGTSSMLFKDFTKHNNWEASTYPSAPKNTRTYPTAEVEKTRHDSSQSARQLKARSTATTISISLSTVSDVFTLPRNNLKSKTNTKKCRDNLNLSGLSSSTCNANSVNKLMKHVMMGNEMMKYPRSESFKMFKKSHWRYFWINPHCEMLCWSKTNPFIEKGRKNQVKSVKIKGMTIIKAPDALKNANLHNEVIVMQTTDKPIVLKAKSKKIHNIWVQAIKQINHKAIFDTKPGI
What is the function of this protein?
Involved in chromosome segregation.  Facilitates nuclear oscillation during meiotic prophase I, the 'horsetail' phase, by acting as a dynein anchor.  Essential for anchoring dhc1 to the cortex.  Required for proper sliding of the microtubules along the cell cortex, which leads to the proper U-turn movement of the nucleus.
What are the official names of this protein?
Meiotic coiled-coil protein 5, Meiotically up-regulated gene 21 protein, Nuclear migration protein num1.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes to the cell cortex during the 'horsetail' phase of mitosis.
Protein: CF251_TETTS
Sequence: MYQQEEYEVNNEGQEDVSKINALNLKWTLGFNFQLTDGVHNLTNEKRKEIFYPVAHTGVIYDYENNTQRLLQGHCNRITATAYCKFSDIIVTADCGPDSMLVVWDASTGIPKKTIFEPHPNGCQALDISQDGQFIVTLSKEANTDTDVQSLSLWEWNKDDEPCLITNEFDRRIKDYQYFVRFNSDDNTEFATTGKTRIVFWRREGEQKGFNYYSPGNIPSLKVLTQTVFIPDNTQVVTGTTDGHIIVWDISLIIEKVDTPKERRAIKLVDLMNKSKKPDGKKGSNSINILKIQDNYLVIGSSNGSIRFYDFQYRIIAWFEDAIIGSISNISFANTPMIEDNEDEDGFDDERKDKGENEPKFICPDFIVVDLDATITMLNYKLFEELDDEKKKGTTLMKSIVSPIIAMSCRPNSNVIGICCENGYLYEWNFQEKSSVLSILRVFDTDKENIPNCIDYSPDGNWLSVATKSGKIHIFDCKEKQWQNSVLEVSENEQGKPKVNMQVFSSDSKNLATMDADYAVSLFTIDHRQFDVNIPEKEWQFVGKHRIHHSEIKSIAFGESKNENDKKYYRLFSIGADMKMVEYEVLEIDYSKQKEKGQQINYIDRLKLKSIYPIEQETIPTACIWYPINMYKEDVLLTVNEEFKIKLWQFMKDNFKFCKKTCLGPIYGGAINKLLILNQNDAQNDYQDKYLAYSTKEKVVGIIKLPLEGNPNQTMGLIAHPDKITSISCSNDGKHFFSSGSDDYCVNVWSVNVQALEQIFATNPNEDPYPKLLEGGEDGQTHQDLKNFFYYSQIRSKDEHTTKARKLDGKVPLIAIPDMMRSMGYYPTNKEIENMQNEIRFSKYLDPGEQVEELDLNMFLKLFVNHRPVQGIGKSKIAESLNTLTKSLSDSAKEIAEQAKGQSVQPKTYNIDGIGEISLQDLKKILTTEGERMTNEEFDECLKILCGENEDQIPQQINVNNLCEDILGFEDLEGEERDDNIEDQYEDEENEEYDQD
What is the function of this protein?
As component of a spoke-associated complex, regulates ciliary mobility by mediating a stable and functional assembly of the radial spoke 3 (RS3).
What are the official names of this protein?
Cilia- and flagella-associated protein 251.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: LUKL2_STAA3
Sequence: MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTAPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
What are the official names of this protein?
Uncharacterized leukocidin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: RS8_GLUDA
Sequence: MSLSDPLGDMLTRIRNAQRARHAACVAPASKLRANVLEALRREGYIRGYAQEDLRKGVAQLRIELKYLDGEPVIKEIHRVSKPGRRVYSKIKELPRVYAGLGVSILSTPRGVLSDAEARAANVGGEVLCRVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: 73C11_BARVU
Sequence: MVSEITHKSYPLHFVLFPFMAQGHMIPMVDIARLLAQRGVKITIVTTPHNAARFENVLSRAIESGLPISIVQVKLPSQEAGLPEGNETFDSLVSMELLVPFFKAVNMLEEPVQKLFEEMSPQPSCIISDFCLPYTSKIAKKFNIPKILFHGMCCFCLLCMHVLRKNREILENLKSDKEHFVVPYFPDRVEFTRPQVPMATYVPGEWHEIKEDIVEADKTSYGVIVNTYQELEPAYANDYKEARSGKAWTIGPVSLCNKVGADKAERGNKADIDQDECLKWLDSKEEGSVLYVCLGSICSLPLSQLKELGLGLEESQRPFIWVVRGWEKNKELLEWFSESGFEERVKDRGLLIKGWSPQMLILAHHSVGGFLTHCGWNSTLEGITSGIPLLTWPLFGDQFCNQKLVVQVLKVGVSAGVEEVTNWGEEEKIGVLVDKEGVKKAVEELMGESDDAKERRKRVKELGQLAQKAVEEGGSSHSNITSLLEDIMQLAQSNN
What is the function of this protein?
Catalyzes the transfer of a glucose (Glc) moiety from UDP-Glc to the C-3 position of the oleanane sapogenins oleanolate and hederagenin, and to the C-28 carboxylic group of the lupane sapogenin betulinate (PubMed:23027665).  The monoglucosylated hederagenin 3-O-beta-D-glucoside is a feeding deterrent of the yellow-striped flea beetle (Phyllotreta nemorum) (PubMed:23027665).
What are the official names of this protein?
UDP-glycosyltransferase 73C11, Oleanolate 3-O-glucosyltransferase UGT73C11.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: DPCD_HUMAN
Sequence: MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGAMGQWQLEVGDPAPLGAGNLGPELIKESNANPIFMRKDTKMSFQWRIRNLPYPKDVYSVSVDQKERCIIVRTTNKKYYKKFSIPDLDRHQLPLDDALLSFAHANCTLIISYQKPKEVVVAESELQKELKKVKTAHSNDGDCKTQ
What is the function of this protein?
May play a role in the formation or function of ciliated cells.
What are the official names of this protein?
Protein DPCD.
What is the protein family that this protein belongs to?
Belongs to the DPCD family.
Protein: CD1E_HUMAN
Sequence: MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW
What is the function of this protein?
T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface.  The membrane-associated form is not active.
What are the official names of this protein?
T-cell surface glycoprotein CD1e, membrane-associated, hCD1e, R2G1.
What are the subcellular locations of this protein?
[T-cell surface glycoprotein CD1e, membrane- associated]: Golgi apparatus membrane; Single-pass type I membrane protein. Early endosome. Late endosome. Note=Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells. SUBCELLULAR LOCATION: [T-cell surface glycoprotein CD1e, soluble]: Lysosome lumen.
Protein: RPOZ_EDWI9
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQTGGKEPLVPEENDKTTVLALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CCR5_MIOTA
Sequence: MDYQVSSPTYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLLFLLTVPFWAHYAAAQWDFGNTMCRLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSMGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CNPY3_DANRE
Sequence: MNVFISVVLFLGSARAASKTGDDEWVHLPNKCEVCKFVSIEMKSAFDETGKTKEVIDTNYRFLDDKGAPPIKYVKSDIRFIEVTENVCSRIMQYNLHKERDGSNRFAKGMSETFSTLHNLVNKGVKVVMDIPYELWNETSAEVADLKKQCDVMVEQYEDVIEDWYKGSQEEDLTTYLCEKHVLKGQDTGCLKETWAGKKGDMAAIAEDKKKKKGKKKKGKDGEDGQKKEKKVKKKKKKSKISDSESSKRRMEAAGFTSDEEEIQKKVPLNQPKTEL
What is the function of this protein?
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1.  Required for proper TLR folding and hence controls TLR exit from the endoplasmic reticulum.  Consequently, required for immune responses (By similarity).
What are the official names of this protein?
Protein canopy homolog 3, Trinucleotide repeat-containing gene 5 protein.
What is the protein family that this protein belongs to?
Belongs to the canopy family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.