PharMolix/UniProtQA huggingface dataset:
Protein: CUPP_DROPS
Sequence: MHLLMSLFGVLAVMQQQLAVRAAAYIPDSDRNTKTLQNDLQVERDGNYRYAYETSNGISATQEGLGGVSVQGGSSYTSPEGSVISVSYVADETGYHPVGDHIPKVPDYILRALEYIRAHPYQVKDYYTGELKTVAHDAAAFNVYTRNIQDQTTPRSRPSSTPKTIYLTHPPTLSDAPTRRPLRQRQNDSRRR
What is the function of this protein?
Component of the cuticle of the pupa of fruit fly.
What are the official names of this protein?
Pupal cuticle protein.
Protein: FBK72_ARATH
Sequence: METTPKRSKTLLMSNGEERRSMTFGIEMLPDDLVLSCLARVPRMYYPILSLVSKRFRSFLTSTELYQTRNLLGSTESFLFVCLRIVNDSNPLRLFTLCRRPNSLTKVMVPILSPDSIPKFLPDVVLVGSNIYVIGGLINNNASHKVMVMDCRSHTWREAQGTCVARVSPSACVLDGKIYVAGGCKNLDATMWMEVFDTKTESWEFVSSPGEEICRDLTSCESIGYDGNVYVESMKTYGLYELHKGRWREGQYSMSRGGSLSSQCVIDNVLYRSWSYMVEWYDSENKLWNSLKGLEKLFIVTNQYVPTKCVNYGGKLAVFWLEKVYAKHLHQETKIWCAVITIERRKKEEIWGTREWFDLVFTTNEEMVDLTHVFAATL
What are the official names of this protein?
Putative F-box/kelch-repeat protein At3g43710.
Protein: SYS_LATSS
Sequence: MLDIRVIRENVQWAKDKLATRGIDAAEIDEVVALDEKRRALIVRTEELKKNRNAASEAIAVAKRNKEDATEQIAAMKNVGAEIKELDAQLAEVKEKVDYILVRLPNFPDDSAPVGLDESFSREERKWSTPREFDFEPLAHWDIGEKLGILDFERAAKVSGSRFVYYKGAGARLERAVYNFMLDQHAKEGYEEMITPYLVNGESMFGTGQFPKFTEDVYTMTNEGEPMTLIPTAEVPLTNFYRDEILDGAQLPIYFTALSPAFRSEAGSAGRDTRGLIRMHQFNKVEMVKFTKPEESFNELEKMTADAENILKALNLPYHVITLATGDASFTSAKTYDIEVWLPAQNTYREISSCSDCTDFQARRAQIRYRDEDGHVNLVHTLNGSGLAVGRTVAAILENYQNEDGTVTIPEPLVPYMGGMTKIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP178_ORIVU
Sequence: MDISISWVVIILLVLSYLILMEKWRAAKLPKNLPPGPPKLPVIGHLHLLGGGLPQHVLRGITQKYGPVAHVQLGEVSSVVLSSTEAARQAMKVLDPAFADRFVNIGSRIMWYDSEDIIFSRYNDHWRQIRKICVSELLSPKNVKSFGYIRQDEMARLIRLFESSEGAAINVSEEISKTVCTIVSRVAFGSVVKDQSLLLNLVKESLRMASGFELADLFPSSWLLNLLCFNKYRLWGMRRRLDNFLDGFLEEHRVKKSGEYGGEDIIDVLYRMQKDSQMKVPITNNGIKGFIYDVFSAGTDTSAATILWALSELMRNPEKMAKAQAEVREILKGKTNVDMAEVHELKYLRSVVKEALRLHPPFPIIPRLCIQESEVTGYTIPANTRILINVWSIGRDPLYWNEPDTFNPDRYDEVPRDIIGNDFELIPFGSGRRICPGLHFGLANIEVPLAQLLYHFDWKLPQGMTAADIDMTEKPGLSGPRKNPLILVPTIHNPTS
What is the function of this protein?
Involved in the biosynthesis of phenolic monoterpenes natural products thymol and carvacrol which have a broad range of biological activities acting as antimicrobial compounds, insecticides, antioxidants and pharmaceutical agents (Ref. 1, PubMed:26156773).  Catalyzes the C2- and C3-hydroxylation of gamma-terpinene to produce carvacrol and thymol, respectively (Ref. 1).  Mediates also the C6-hydroxylation of (4S)-limonene to form carveol and the C3-hydroxylation of (4R)-limonene to generate (+)-trans-isopiperitenol (Ref. 1).
What are the official names of this protein?
Cytochrome P450 71D178, (+)-trans-isopiperitenol synthase, Carvacrol synthase, Carveol synthase, Gamma-terpinene hydroxylase, Limonene hydroxylase, Thymol synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL10_BACC4
Sequence: MSKVIETKQQVVTEIADKLRASKSTIVVDYRGLTVSEATELRKQLREAGVEFKVYKNSLTRRAAESAEMAELNEFLTGPNAIAFSNEDVVAPAKVLNDFAKDHEALEIKAGVIEGKLVTLDEVKAIATLPSREGLLSMLLSVLQAPIRNLALATKAVADQKEEQGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SDHE_ACIAD
Sequence: MSEELTLEERKVIYRARRGLKEIDVYFDPYVKNYYLTAPASEKALFAELVAQEDPDLLDWFMEVSEPPQVELKQLIQKLKHYVHG
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_MYCTA
Sequence: MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GD_EHV1K
Sequence: MPAVLLVLYVNPPPSVCILTQKLSLGLYNQWWRVCRSVPPPWYVFFNKRSMSTFKLMMDGRLVFAMAIAILSVVLSCGTCEKAKRAVRGRQDRPKEFPPPRYNYTILTRYNATALASPFINDQVKNVDLRIVTATRPCEMIALIAKTNIDSILKELAAAQKTYSARLTWFKIMPTCATPIHDVSYMKCNPKLSFAMCDERSDILWQASLITMAAETDDELGLVLAAPAHSASGLYRRVIEIDGRRIYTDFSVTIPSERCPIAFELNFGNPDRCKTPEQYSRGEVFTRRFLGEFNFPQGEHMTWVKFWFVYDGGNLPVQFYEAQAFARPVPPDNHPGFDSVESEITQNKTDPKPGQADPKPNQPFKWPSIKHLVPRLDEVDEVIEPVTKPPKTSKSNSTFVGISVGLGIAGLVLVGVILYVCLRRKKELKVCTERLDSPTLDL
What is the function of this protein?
Envelope glycoprotein that binds to host cell entry receptors.  May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity).
What are the official names of this protein?
Envelope glycoprotein D, gD, Glycoprotein 17/18.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein D family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs.
Protein: BPT_RUEPO
Sequence: MRHTLPIAPQFYVTAPQPCPYLAGRMERKLFTALQGEGAERLNNALSQQGFRRSQNVLYRPSCADCAACLSARIDVSAFRASRSQKRAMRRNAHLTRRATSPWATDEQYELFRRYLDSRHADGGMADMDVFEFAAMIEETPIRSRVIEYAHRDTRALIGVSLTDVLDDGLSMVYSFYDPDLHRDSLGTHMILDHIAIAREAGLPYVYLGYWVPGSPKMGYKSRFSGLEIYLGGRWQAMTDPEAHDAIRHPLSTDPIAEQVANIQLPDRWPTGD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXD_SALNS
Sequence: MVFRIASSPYTHNQRQTSRIMLLVVIAALPGIAAQTWFFGWGTLFQIVLAAITALVAEAIVLRLRKQSVASHLQDYSALLTGLLLAVSIPPLAPWWMVVLGTGFAIIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPYEIAATTPDMLDTLRMIFTGHTASGGDMTLLRIGIDGISQATPLDTFKTSLRAGHSVEQIMQYPIYSGALAGVGWQWVNLAWLVGGVFLLWQKAIRWHIPVSFLLTLALCAALGWLFSPATLASPQLHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGVLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURB_AGARV
Sequence: MNQTFVKSVTEQLPQLGLLQDEPMKKHTTFRIGGPADYYAEPDMSRISKLIEMAKACDMPVTVIGNGSNLLVGDKGIRGLVIGIGKGLSEIEVTEAVAQDFTAQDNCHIITAGAGAILAAVAAKAAEASLSGLEFASGIPGSVGGAVVMNAGAYGGEIKDVLIDATVLTADGELKTVTRDELDLSYRHSIVPEKGYIVLSARFRLTPKPKDEIKSYMAELRAKRVEKQPLEYPSAGSTFKRPEGYFAGKLIMDAGLRGYSVGDAQVSEKHCGFVVNKGEAAAADVLTLIKDVQETVLKQFGVKLEPEVKMIGEF
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_ALIFM
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGSGVEIIDISPMGCRTGFYMSLIGTPAEQAVADAWVSSMEDVLKVEAQNKIPELNEYQCGTYEMHSLDEAKAIATTVLASGISVNKNDELALSDSMLKELSNH
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: TFXD_RHILT
Sequence: MSDENQHGFYRTSFEYASISWRRMIPNVADTIVVTLIGATALQVASNVLITILTLNIAFLNFCSLICMHNLKRGAKADVFAAIVRAACMMIGVYLALIAVSVATLEGAPRTQTIAFIALSALRPFVAGWNAYCAEVFFAQGKRQIVRSVITRSSLIYAGVNLLFVGLSHFAGTQNSIISLLIGVYLALFHNALAYARILPTEWRFSRQDLKDVFSLRKLDLVGIGAGLSASFINMLEMGFLALVGWVVAAKFPQIAVFYFPFFTLVELTSGLAIGLGRSVTERLITPRPFPRLHVLIAVYSTYSLLCFLIYVGLIGVSNRDIFALPLSLAGLALLFLICDGLQLVVRGYTLAKADGGKLTHLSAIAYLASGVILALAAVLGSVQALAIALVLGPLFLAISIPAVQSRTALNALPNR
What is the function of this protein?
The actions of the proteins TfxB, TfxD and TfxF are implicated in the processing of the inactive trifolitoxin (TfxA) precursor into the active peptide.
What are the official names of this protein?
Trifolitoxin-processing protein TfxD.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS7_VIBVU
Sequence: MSKQQKILFIDRDGTLIVEPPVDFQVDRLDKLKLEPFVIPSLLSLQDAGYRLVMVTNQDGLGTDSYPQEDFDAPHNMMMEIFESQGVKFDDVLICPHFEKDNCSCRKPKLGLVKEYLQAGKVDFQNSFVIGDRQTDLQLAENMAIRGIQYNPEIMGWKRILKDLTVKARVAEVVRTTKETDIKVFVNLDEQGGNAISTGLGFFDHMLDQIATHGGFQMVCKVEGDLHIDDHHTVEDTALALGQALKEALGDKRGIGRFGFSLPMDECLAQCALDLSGRPYLKFDAQFSREQVGDLSTEMVVHFFRSLTDTLACTLHLSSAGNNDHHIIESLFKAFGRTLRQAIKVEGTELPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPB1_METJA
Sequence: MISAKSKTKRITITFEIPEDIDAKKFKDDVKRYVRYKLLANKLYELLEGENIEEIEEEIRKRRE
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC1 (Potential).
What are the official names of this protein?
Putative antitoxin VapB1.
Protein: Y1917_HYDCU
Sequence: MAITDWHENDRPREKLLKFGAPHLSDAELLAIFLRVGVKGKSAVELAQDLLDHFGSLERLLNADEAAFCEAKGLGQAKYVQLKAVLEMSRRHFESGLKKGEALTQPEKVARLLQHHIGHQSREIFGLVLLDQQNQFIQFVPLFTGTINQATVHIREVLKTVLDHHAAAVILAHNHPSGDPTPSQSDRDLTHQIQQGLQLIETRCLDHIILGDHGRWYSFTQQGIL
What are the official names of this protein?
UPF0758 protein Tcr_1917.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: YHIS_ECOLI
Sequence: MSIDFTPGIINTYHGDIYNCTTNTDNAKTPDTPKWPCDNWEEQQPINSTFSGEGYISDQYDLAQHQLQQINACHTNTTYTNADYSKVVAQLVSLITNIETISSTQLTQQTQSILNQINNIRYEKNKSAECRIIVIANPKPDKAIITKISVEEGIPITFSVQTMFSDTNFIAEQRADLPTNIKDIQSLYQKMTKLYIEHSENKNRMKVFAGTNFIDFNMTGQNLSGFVLTLSRFYFEDLLNINFTDANLGKVRISGEILLG
What are the official names of this protein?
Putative uncharacterized protein YhiS.
Protein: TXI3_ERAAG
Sequence: MKLQLMICLVLLPCFFCEPDEICRARMTNKEFTYKSNVCNGCGDQVAACEAECFRNDVYTACHEAQKG
What is the function of this protein?
Toxin that paralyzes insects.  May have a direct effect on the insect central nervous system.
What are the official names of this protein?
U1-agatoxin-Ta1c, U1-AGTX-Ta1c, Insecticidal toxin 3, TaITX-3.
What is the protein family that this protein belongs to?
Belongs to the helical arthropod-neuropeptide-derived (HAND) family.
What are the subcellular locations of this protein?
Secreted.
Protein: M2_I71A1
Sequence: MSLLTEVETPIKNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: KPRS_SYNY3
Sequence: MSAVSRIATLTRQSMLSALSDNNRLRLFSGSSNPSLSQEVARYLGMDIGPMLRKRFADGELYIQIQESIRGGDVYLIQPCCHPVNDNLMELLIMIDACRRASARQITAVLPYYGYARADRKTAGRESISAKLVANLITGAGAQRVLAMDLHSAQIQGYFDIPCDHMYGSPVIIDYLKSKQLTDLVVVSPDVGGVARARAFAKKLNDAPLAIIDKRRQSHNVAEVLNLIGDVDGKTAVLVDDMIDTAGTLSEGSRLLRAQGARQVYACATHAVFSEPAINRLSGGLFEEVIVTNTIPVPDDHHFPQLTILSVANLIGEAIWRIHEESSVSSMFR
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_DEHMB
Sequence: MVSLKTGILGGTFDPIHTGHLILADEVKNRLGLDEVIFIPTGQPYYKADKTISPAEDRLNMVKLAISDKPYFRVMDIEIKRSGPTYTADTLNDLKTILPEKTELYFMLGWDNLEALPRWHKASEIIRLCRLVAAPRIGQVKPDVDELDDKLPGLQQSLILLSKPEVDISSSLVRERVENGQGVEHLVPAAVASYIKKHNLYCRK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: JMJD6_CAEBR
Sequence: MSLGKDRYSLPRSYKRVSHAKEKARPELRKFGWDTLGYAESFNPPPLKDTIPRVDGKKISVDEFRRDFERPRIPVILTGLTDDWNAHEKWTLERLSKKYRNQNFKCGEDDHGNSVRMKMKYYHDYMLNNRDDSPLYIFDSSFAERRKTKKLSEDYKVPKFFEDDLFHYADHKKRPPHRWFVMGPARSGTAIHIDPLGTSAWNSLLLGYKRWVLIPPNAPRDLVKPMAHEKGKHPDEGITWFQTVYKRVRSPAWPKEYAPIECRQGPGETMFVPSGWWHVVINEGLTVAVTHNYCSVENLHLVWPKTVRGRPKLSKHWHRKLAESRPEVLKIINSCTDTPPQSLNDSSSDSSSSSSSSDDSSDSETEEDSGRCGLGNRKRRNDVCTSECPEKISNSMV
What is the function of this protein?
Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase.
What are the official names of this protein?
Bifunctional arginine demethylase and lysyl-hydroxylase psr-1, Phosphatidylserine receptor 1.
What is the protein family that this protein belongs to?
Belongs to the JMJD6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRIC1_DROPS
Sequence: MSSLSAPPGGCGGDVAAAPATATSTATATATATATATATGSMEPAMVPRTANLLACKQWWRVCFLYGDQQKYYRQLYSKAAAQRLAGANQENDNAARGAGAGEGEGQEYDTVAMGDGDFIAAQLDAGEDVDDGIDLGDSSQPGGGATPTATATAGRPLFPLSSSPRRSKKLLRSLRAHVKGESRPEKPAKAAKPQSEPSSELTKRNARVTVLDDPFLFGIDADHLGDLVRGKQYSPLEATENIAKFYELQLETTEATAQVLEIIEQEEEPPEPPKPALPPKQKQPRPVPPLPARITQPAVLQPLTAGDLQFLNLSLRHRSLPRSMKPFKDPHDISFTFNELDTSTSATAAAAAAAVAAADVATGVGVGSSQQESNEPISRTPLTQISYLQKIPTLPRHFSPSGCPQGLPPPPALAGCGSALGLPSSSSASALYAAQNGGMLPTSPLPLQRHQQYLPPHHQQLPPLGAGPGQGQGHGLALGPGGAGLPQYSPAVSGCSSTAKYSNAQLPPHHHQLSPALSTPSPPSLLHHPAAGTSASAHAPFLAGPHMDMQRQSHSDDDSGCALEEYTWVPPGLRPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKELRLFSTQRKRDALGRGNVRQLMSARPCDGCDELISTGDIAVFATRLGPNASWHPACFTCCICRELLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSIACSKGEPPTPSDSSGTGMYTTPTPPTQRVRPQTRITSSHASSSPPMSPQQQQQHQASFNQAMYQLQTQQLEAAGGPVSQSQSYATSDSDAGVVKDLEHCRSGDHAGGGDFTDFSGGRASSTSHNMSPLNSPGDFQPHLMPKPMELQRDGVYNFNEMSSNLDTAWPAKPPLGATHSYQLQRQLMENQHTSSMPELAGKGPMLQHQMAAHFGQQPALHSSAQQFQHEYADIMHPPPPPPERGAVGEVPELPTPNLSVASTALPPELMGSPTHSAGDRSLNTPLSAHSATHGPTHPVSILSGASSSSPMSGEPAKKKGVRFEGIPDTLPRSRSYSGNGAGTSGGGDKDRDRDRERDRDRDRDKGGDKDRESGRHGPGHSSRRRRRRKSTSSTSSGNHHRSGSGHRSHSTTRADTYAPAQPLSSSYQGPPSVLQADSETAHKSPRQQREREREESAEESDVCSTCSSSSSSSEDYMMMYQLPQRRHYGGVRVSYVPNDALAYDRKRKPAEMAGDKDKNCIIS
What is the function of this protein?
Acts in a planar cell polarity (PCP) complex; polarization along the apical/basal axis of epithelial cells.  PCP signaling in the wing disk requires the receptor fz and the cytoplasmic proteins dsh and pk.  These act in a feedback loop leading to activation of the jnk cascade and subsequent polarized arrangement of hairs and bristles.  Dgo and pk compete with one another for dsh binding, thereby modulating fz dsh activity and ensuring tight control over fz PCP signaling.  Vang, stan and pk function together to regulate the establishment of tissue polarity in the adult eye (By similarity).
What are the official names of this protein?
Protein prickle.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL23_PSEA7
Sequence: MNQERVFKVLLGPHISEKATGLADGKSQFVFKVATDATKLEIKKAVESLFSVKVQRVTTLNVKGKTKRTARGLGKRNDWKKAYIALQPGQDLDFATSAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SERB1_ARATH
Sequence: MAATTNSFLVGSNNTQIPALKPKSSSQSFLHLSKPNTVNFVSKTKPVAVRCVASTTQVQDGVRSGSVGSQERVFNFAAGPATLPENVLLKAQADLYNWRGSGMSVMEMSHRGKEFLSIIQKAESDLRQLLEIPQEYSVLFLQGGATTQFAALPLNLCKSDDTVDFVVTGSWGDKAVKEAKKYCKTNVIWSGKSEKYTKVPSFEELEQTPDAKYLHICANETIHGVEFKDYPVPKNGFLVADMSSNFCSKPVDVSKFGVIYGGAQKNVGPSGVTIVIIRKDLIGNAQDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLVFEDLLEQGGLKEVEKKNQRKADLLYNAIEESNGFFRCPVEKSVRSLMNVPFTLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKHA
What is the function of this protein?
Involved in the plastidial phosphorylated pathway of serine biosynthesis (PPSB).  Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine.
What are the official names of this protein?
Phosphoserine aminotransferase 1, chloroplastic, AtPSAT1, Phosphohydroxythreonine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IFI5B_MOUSE
Sequence: MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ
What is the function of this protein?
May act as a transcriptional regulator in the myeloid lineage.  Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways.
What are the official names of this protein?
Interferon-activable protein 205-B, Ifi-205-B, Interferon-inducible protein p205-B, Myeloid cell nuclear differentiation antigen, Protein D3.
What is the protein family that this protein belongs to?
Belongs to the HIN-200 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NFUA_XYLF2
Sequence: MIQISDTAKSHFLKLIQREGVPGMGVRLSAVDPGTPRADARLEFADPSELVGDEWLIDCGDFTLYVASASVAWLDGAEIDYVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENEINPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMADVTLKQGVEKTLMDRVHGVIAVRDATDHSTGAAPYISRDFSP
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: EIF3J_PICGU
Sequence: MSWDDDDFDVPATKTAGVSWEDEDNDDPLLESWDIDEEEVARKKKEEEAKKKAEKEALKQKQQEAKNKKLSQKSGERKLLDIDLIDEETRQELLRKAQVTSDLNNAADLFGGLGVANDDDFDVNEHPRERAAKLAAAKQAAKPAAPRLTRDSPLEMHPLFQPTDKAEYEKLRKALATSLQQLAEDSPLNYSSALGIDLIRDAAQPLSLENVRKVISTLNVIVKDKERAERQARLKKAGGTATGGAGKKKAKPAVKTNVSDMYKKDAGDDFDDFDDDDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j, Eukaryotic translation initiation factor 3 30 kDa subunit homolog, eIF-3 30 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.