PharMolix/UniProtQA huggingface dataset:
Protein: NU170_YEAST
Sequence: MFQSFFHNNGPAAAGETFSDSRSYPLTNHQEVPRNGLNELASSATKAQQQPTHILNSYPITGSNPLMRASAMGATSGSINPNMSNMNEHIRVSGMGTSKPLDLAGKYIDHLQHKDSNTPVLDERSYYNSGVDYNFSREKNGLGAFTPFEKQDVFNIPDEILHEFSTSQTKTDMGIFPELNRCWITIDNKLILWNINNDNEYQVVDDMKHTIQKVALVRPKPNTFVPAVKHLLLISTTMELFMFAISLDKATNELSVFNTHLSVPVQGIDVIDIVSHERSGRIFFAGQASGLNIWELHYSGSDDWFNSKCSKVCLTKSALLSLLPTNMLSQIPGVDFIQALFEDNSNGNGGFSQETITQLTIDQQRGIIYSLSSKSTIRAYVITEKSLEGPMSIEPAYISRIIGTTTARAAPILGPKYLKIVKISSVAPEENNNLFLVALTVGGVRLYFNGSMGRFNIEALRLESIKFPPSSVTPEVIQQELLHQQQEQAKRSFPFFSNLMSSEPVLLKFQKKSSVLLETTKASTIISPGIFFSAVIKSSQQTHQQEKKENSSVTGTTATAGSKTVKQQPVTLQHKLFVSVPDYGILKTHGKYVENATFLETAGPVQQIIPLSGLFNATTKPQGFANEFATQYTSETLRVAVLTSTSIEIYKYRTPDEIFEDLIDNPLPFVLNYGAAEACSTALFVTCKSNKSEKLRSNALTFLTMGIPGVVDIKPVYNRYSVSTVSSLLSKPTLSTATTNLQQSITGFSKPSPANKEDFDLDDVILSPRFYGIALLITRLLRDIWGRHVFMTFTDNRVTSHAFISSSDPITPSINNLKSDEISQNRNIISKVSISKDCIEYYLSSINILNEFFITYGDSISQISAPYVLANNSNGRVIDKTEEVANQAESIAINAMIKMVQSIKEGLSFLNVLYEESEVEGFDNQYLGFKDIISFVSLDVQKDLVKLDFKDLFAPNDKTKSLIREILLSIINRNITKGASIEYTATALQERCGSFCSASDILGFRAIEHLRRAKEIGLRNYDSLNYHLKNATALLEQIVDDLSIEKLKEAVSMMLSVNYYPKSIEFLLNIANSMDKGKLACQYVANGFLENDDRKQYYDKRILVYDLVFDTLIKVDELAEKKQSSKTQNQISISNDDEVKLRQKSYEAALKYNDRLFHYHMYDWLVSQNREEKLLDIETPFILPYLMEKAGSSLKISNILWVYYSRRSKFFESAEILYRLATSNFDITLFERIEFLSRANGFCNSVSPLSQKQRIVQLASRIQDACEVAGIQGDILSLVYTDARIDSAIKDELIKTLDGKILSTSELFNDFAVPLSYHEIALFIFKIADFRDHEVIMAKWDELFQSLRMEFNNTGKKEDSMNFINLLSNVLIKIGKNVQDSEFIFPIFELFPIVCNFFYETLPKEHIVSGSIVSIFITAGVSFNKMYYILKELIETSDSDNSVFNKEMTWLIHEWYKSDRKFRDIISYNDIIHLKEYKIDNDPIEKYVKNSGNNLGICFYKE
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  NUP170 probably plays an important role in NPC assembly and organization.  In addition it is required for chromosome transmission fidelity.
What are the official names of this protein?
Nucleoporin NUP170, Nuclear pore protein NUP170.
What is the protein family that this protein belongs to?
Belongs to the non-repetitive/WGA-negative nucleoporin family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: RUNX2_HUMAN
Sequence: MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
What is the function of this protein?
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed:28505335, PubMed:28738062, PubMed:28703881).  Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification.  CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters.  In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity).  Inhibits KAT6B-dependent transcriptional activation.
What are the official names of this protein?
Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, CBF-alpha-1, Oncogene AML-3, Osteoblast-specific transcription factor 2, OSF-2, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEA2-alpha A, PEBP2-alpha A, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: FBPAP_METS5
Sequence: MRSTVSVIKADIGSLAGHHVVHPDTMAAANRVLAEAKRQGIILDYYITNVGDDLELIMSHTRGELDTKVHETAWDAFKEATKVSKELGLYAAGQDLLSDSFSGNLKGMGPGIAELDIEERPSEPIAIFMADKTEPGAFNLPLYKMFADPFNTAGLVIDPTMNEGFKFEVLDVYEGQSVVLNSPEEMYSLLGLIGTPARYVIRRVYRKADNMIGSVTSIERLNLIAGKYVGKDDPVLIVRLQHGFPALGEALEAFSFPYLVPGWMRGSHYGPIMPVSQRDAKATRFDGPPRLIGLGFNVKNGKLTGPSDLFDDPAFDETRRMASVITDYMRRHGPFMPHRLEPTEMEYTTLPTLIEKLKPRFKKEEDVKKAKPSVYTSKDQGMD
What is the function of this protein?
Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
What are the official names of this protein?
Fructose-1,6-bisphosphate aldolase/phosphatase, FBP A/P, FBP aldolase/phosphatase.
What is the protein family that this protein belongs to?
Belongs to the FBP aldolase/phosphatase family.
Protein: CC014_MOUSE
Sequence: MASLFTQEIHLSKRHEEILSQRLMLLQKMKNKFGDENTERASLLQATETASRRNLRLLKDIDAAEEAFQTKLIPHPQPSMLSLETRYWASVEEHIPKWELFLLGRAPYPIGAENQNEVPFVQTEAKL
What are the official names of this protein?
Uncharacterized protein C3orf14 homolog.
Protein: MGSA_HISS2
Sequence: MQTTYRKLAKNKKIALVAHDHCKQDLIQWCQTNRTLLQPHILYATGTTGNLIHQETNLEIKNLLSGPMGGDQQLGGLIAEGKIDLLIFFWDPMNAVPHDPDVKALMRIATVWNIPVAMNIATADFLISSPAFQQETEIRIPDYQGYLKERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: GLMM_SYNP2
Sequence: MMIMPEEGHPLSRMLASYPPQALRCDLPAGSLFGTDGIRGKAGDLLTAPFALQVGYWAGQVLQETAARRAPVIIGQDSRNSSDMLAMAIAAGLTASGLEVWHVGLCPTPCVSYLARTTDAIGGIMISASHNPPEDNGIKFFSDAGTKLLKDLSAKIEAGLRGDRLENILSQTNNCGSYQHQKELTQQYRNAVFATLPQGLSLDGLKIVLDLAWGASVHLAPELFQALGAEVIALHHQPDGNKINVNCGSTHIDQLQGAVQFHNADLGFAFDGDADRVIAVDNTGRIVDGDYILYLWGKQLQAAGQLPNNLIVGTVMANLGFERAWEKLGGQLHRTAVGDQYVQAAMWQTGAMLGGEQSGHILCHHHSVSGDGIQTALHLAALVREAGVPLNELIDQSFQTYPQFLKNVRVEDRDRRLNWQNCDVLQTEIAKAEAAMGDKGRVLVRASGTEPVIRVMVEAEEQYLAEYWTQHLVNVVQSHLG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PYRD_CANAL
Sequence: MFRPSIKFKQSTLSIIARRLKSSAQHQPLRSSFVPSPIVFVAGLAVAAVGGYYCLDSRSAIHEYVLCPLIRTFTDAESGHKLGIFFMKYGLSPRLLDDGKNDQSDVLGVQVFGHKLKNPIGLAAGLDKDGEAIESLFNCGFSYVEIGSITPEPQPGNPQPRFFRLPKDDAVINRYGFNSSGHFNVLATLKLRFNKLLNKFGTSHSSEQHPFSNAFQQGKLLGINLGKNKFGDEVNDYVKGVERLGPYADVLVINVSSPNTPGLRDLQSEAKLTNLLTTVVKERNVLGKNLLGNKPPVLVKVAPDLTEPEIESIANSAKEAKVDGIIISNTTIQRPVDRLLTTDKQLINQAGGLSGKPLKPLSLKALRTLRKYTKDSDLVLIGCGGISNGKDALEFGKAGATFIELYTAFAYKGPGLVGKIRDELAEELRKEGKTWEQIIGSDDK
What is the function of this protein?
In the de novo pyrimidine biosynthesis pathway, catalyzes the stereospecific oxidation of (S)-dihydroorotate to orotate with reduction of flavin and the transfer of electrons to ubiquinone, which is part of the repiratory chain.  Does not use fumarate and NAD as electron acceptors.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOD, DHODase, DHOdehase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PLSY_PECCP
Sequence: MSVTALGMMLIAYLCGSISSAILFCRIAGLPDPRQHGSGNPGATNVLRIGGKAAAATVLVFDVLKGMLPVWAAYALGVSPLYLGLTAIAACLGHIYPVFFHFRGGKGVATAFGAIAPIGWDLTGLMTGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVAMLSCLILMRHHDNIQRLWRGQESKIWNKLRKKKQPEDEKTSPEE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNPA_RHOJR
Sequence: MLPEPHRLRRHSDFSMTVRRGRRMGRRDLVVHAFDRAQADELVSSGGPRFGLVVSKAVGPAVIRHRVARRLRHICIDLVDVVPRGTDVVIRALPGAATASSRDLEKQLRAGLLRLDLLAPVSTSA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: NGFV3_PSEAU
Sequence: MSMLCYTLIIAFLIGIWAAPQSEDNVPLGSPATSDLSDTSCAQTHEGLKTSRNTDQRHPAPKKVDDQEPGSVANIIVDPKLFQKRQFQSSRVLFSTQPPPLSRDEQSVEFLNNEDALNRNIQAKRQNHPVHDLGEHSVCDSISEWVTKTTATDIKGNTVTVEVDVNLNNEVYKQYFFETKCRNPNPVPSGCRGIDSRLWNSYCTTTQTFVKALTMEGNQASWRFIRIDTACVCVITKKTDNL
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor 3, v-NGF-3, vNGF-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: SN25A_CARAU
Sequence: MAEDADMRNELSDMQQRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKDAEKNLNDLGKFCGLCSCPCNKMKSGGSKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTDDARENEMDENLEQVGGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG
What is the function of this protein?
May play an important role in the synaptic function of specific neuronal systems.  Associates with proteins involved in vesicle docking and membrane fusion.
What are the official names of this protein?
Synaptosomal-associated protein 25-A, SNAP-25A, Synaptosome-associated protein 25.1, SNAP-25.1.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Synapse, synaptosome. Cell membrane. Note=Complexed with macromolecular elements of the nerve terminal.
Protein: U79B5_ARATH
Sequence: MGSKFHAFMYPWFGFGHMIPYLHLANKLAEKGHRVTFFLPKKAHKQLQPLNLFPDSIVFEPLTLPPVDGLPFGAETASDLPNSTKKPIFVAMDLLRDQIEAKVRALKPDLIFFDFVHWVPEMAEEFGIKSVNYQIISAACVAMVLAPRAELGFPPPDYPLSKVALRGHEANVCSLFANSHELFGLITKGLKNCDVVSIRTCVELEGKLCGFIEKECQKKLLLTGPMLPEPQNKSGKFLEDRWNHWLNGFEPGSVVFCAFGTQFFFEKDQFQEFCLGMELMGLPFLISVMPPKGSPTVQEALPKGFEERVKKHGIVWEGWLEQPLILSHPSVGCFVNHCGFGSMWESLVSDCQIVFIPQLADQVLITRLLTEELEVSVKVQREDSGWFSKEDLRDTVKSVMDIDSEIGNLVKRNHKKLKETLVSPGLLSGYADKFVEALEIEVNNTKFS
What are the official names of this protein?
UDP-glycosyltransferase 79B5.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: MALB_MAAAM
Sequence: ATSNSKPTQVLLATFLTFFFLLLNNVNSSDELSFTINNFVPNEADLLFQGEASVSSTGVLQLTRVENGQPQQYSVGRALYAAPVRIWDNTTGSVASFSTSFTFVVKAPNPTITSDGLAFFLAPPDSQIPSGRVSKYLGLFNNSNSDSSNQIVAVEFDTYFGHSYDPWDPNYRHIGIDVNGIESIKTVQWDWINGGVAFATITYLAPNKTLIASLVYPSNQTSFIVAASVDLKEILPEWVRVGFSAATGYPTQVETHDVLSWSFTSTLEANSDAATENNVHIARYTA
What is the function of this protein?
Sialic acid-binding lectin specifically recognizing the trisaccharide sequence Neu5Ac/Gc-alpha-2,3-Gal-beta-1,4-GlcNAc/Glc.
What are the official names of this protein?
Bark leucoagglutinin, Bark leukoagglutinin.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: GLMU_BARQU
Sequence: MRSCLSIVLAAGEGTRMKSSLPKVLHKIAGLPLVCHVIKQIELAGASQLAVVVGAGAQDVTHVVQSFIKSVMIFEQKERLGTAHAVLSARLALQKEVDDVLIVFGDTPLIKQDSLLKVREQLAVGADVVVAGFYASDPTGYGRLLEKNGKLIAIVEEKDASDEEKKISFCNGGILALNGKRALSLLEKVNNYNSKQEYYLTDIVSIASREGLEVQVVEVPFDNIVGINNCFELFEADSLWQKRKARDLMLSGVTILKPETVYFSYDTEIEQGVVIEPNVYFGLGVKVQSGAVIHAFSYLEGAVVGIDAQIGPYAHLRPGTELARSVKIGNFCEVKKAKIGEASKINHLSYIGDAEIGAQTNIGAGTITCNYDGFHKYKIVIGDHAFIGSNSALVSPLMIGNGSYIASGSVITEDVPINSMAFGRARQVTKKDYAAKLRVRLSGNQQKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_DAUCA
Sequence: MAKGKDVRITVILECTGCVRNGVNKVSTGISRYITEKNRHNTPNRLELRKFCPFCYKHTMHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PETD_STIHE
Sequence: MAVIKKPDLSDPVLKMKLAKGMGHNYYGEPAWPNDLLYIFPVCIFGTFAIVIGLSVMEPAAMGEPANPFATPLEILPEWYFYPVFQLLRVIPNKLLGVLLMAAVPAGLLTVPFIENINKFQNPFRRPIATTVFLLGTVVAVYLGIGSTFPIDQSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: VC04_SWPVK
Sequence: MNSLLLRLHDFFKHGIMCDIKIVSIENNKTISAHRLILSMYSKYFYNIFNSDFIDKNNDEIYICADYDILYIILEFMYTGNIVLTKDNIELVIQVCDYLCIDSLIKICEEYICGIIDETNCIHLLNFSDTYNLQRLREMSKWYLPKIINNNKLVVELDIDDMILIIKEIKYIACEYIVKKIILNWIVHKDERIIYTKKLMKHINDQDHYTSLSDIELYNNIRERIYDNKEHDVDISHNFIIMVGGKKIFNITAFNPLSNKKHIIDRYDDMFGCKTHFSVVYLNSILYIIGGKKRGYFTKEVLSYNIKNKLWCYEPELNYFRYDTSVCVSNGMIYSIGGKDTNGYMTNIVEFWKPEWKSWYDGQHLCYPRCYMSLVDYNNEVYTIGGLKTSITDEFNIEMIVSDDAVEKLTDHSWMKLKQFPIAKSGISSIVYNDFIYCIGGRIDTPHISIEHTNDVYIYSSRDDCWKYLSNTNVKRSFCLSCVFNNELYIIGGYNTNSVEKYNKLKNTWKRLNDIPKFEECVNEASAIYL
What are the official names of this protein?
Protein C4.
What is the protein family that this protein belongs to?
Belongs to the poxviruses Kelch family.
Protein: RL6_NOSP7
Sequence: MSRIGKRPITIPAKVQVAINGTNIVVKGPKGELSRTLRDNVSLSQEGEILHVNRRDETRTSKQLHGLSRTLVANMVEGVSQGFQRRLEIQGVGYRAQLQGRNLVLNMGYSHQVQIEPPDGIQFAVEGTTNVIVSGYDKEIVGNTAAKIRAVRPPEPYKGKGIRYAGEVVRRKAGKTGKGGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PAX5_HUMAN
Sequence: MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH
What is the function of this protein?
(Microbial infection) Plays an essential role in the maintenance of Epstein-Barr virus genome copy number within the host cell by promoting EBNA1/oriP-dependent binding and transcription (PubMed:31941781).  Participates also in the inhibition of lytic EBV reactivation by modulating viral BZLF1 activity (PubMed:23678172).
What are the official names of this protein?
Paired box protein Pax-5, B-cell-specific transcription factor, BSAP.
What are the subcellular locations of this protein?
Nucleus.
Protein: GFA_RHIME
Sequence: MLKLHPSIDNGFPPASPGFAGGTLKCKCASNPVTVRIGSQTAHNHACGCTKCWKPEGAIFAQIAVVGRDNVNVTSGAEKLQVVDPSATIQRYACRDCGTHMYGRIENTKHPFYGLDFVHTELSDETGWSPPEFAAFVSSIIESGVNPESMPEIRARLTELGLQPYDCLSPPLMDAIATHIAKQTGALPA
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: FADA_ENTCL
Sequence: MEKVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALDPAALDDIYWGCLHQTLEQGFNLARNASLLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHMGHVPMSHGVHFHPGMSRNVAKAAGMMGLTAEMLSRLHGISREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFSYDEVIRPETTVEALSTLRPAFDPVTGTVTAGTSSALSDGAAAMLVMSESRARELGLTPRARVRSMAVVGCDPSIMGYGPVPASKLALKKAGLTASDIDLFEMNEAFAAQILPCIKDLGLMGQIDEKINLNGGAIALGHPLGCSGARISTTLINLMEGKDAQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_PSET1
Sequence: MHCPFCTAKDTKVIDSRLVGGGHQVRRRRECNDCHERFTTFEGAELVMPRVIKQDGSREPFNEDKLLNGLNRALEKRPVSTEQVEEVVNIIKSQLRATGEREVSSHLVGECIMEALKKLDKVAYVRFASVYRSFEDIREFGEEIARLGE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RS11_MACCJ
Sequence: MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFRGSRKSTPFAAQMASETASKAAMEHGLKTVEVTVKGPGQGREAAIRALQSAGLEITAIKDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HFQ_BART1
Sequence: MAERSQHLQDVFLNTVRKQKISLTIFLVNGVKLTGIVTSFDSFCVLLRRDGHAQLVYKHAISTIMPGQPVQMFEGESPE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: LEU1_ECO5E
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRATEVEKELQRKAQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: GRPE_ECO57
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_BRUO2
Sequence: MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: Y425_CAUVC
Sequence: MIKINHLEIRFQGEQNSPYPGNGNLSNNAFLRIRAILERLGFSQRGIHGPVVHASSQIGGRDLRPAHGRGLELWLHPAGRGSGLPHPWRPALRLRAHRQPDRAPPARASEQPLRQGRRALRRRPDQRRHRPRMTAAALRLGAARIGPGLLAGLLMAVLAKLLSQSLHAPAPLLAVVLGMMLGALGLQGQLGAGLDVFAKPGLRLGVAMMGAQISWSEFAALGGPAVLASGAVVLGGLGIGALAGAALGLPLAEALIAAAACSICGASAALAASQAAPSSPENQRTTALVIVGVNLLSTVAMLAYPPIANALGLTAHQAGVFFGLSIHDVAQVAGAGASVSPEVAGTAALAKLSRILWLGPAVVLIGLMLTRTAQGGRISGLQAPPLFVWGFAALAAARGLNLIPPALVSALGACSGFLLLAGVGAISAKLGPKALLEVKPRLAILLVTLTVAVAILAYALTRIFF
What are the official names of this protein?
UPF0324 membrane protein CC_0425.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.