PharMolix/UniProtQA huggingface dataset:
Protein: ARP2_YEAST
Sequence: MDPHNPIVLDQGTGFVKIGRAGENFPDYTFPSIVGRPILRAEERASVATPLKDIMIGDEASEVRSYLQISYPMENGIIKNWTDMELLWDYAFFEQMKLPSTSNGKILLTEPPMNPLKNREKMCEVMFEKYDFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLSHLTRRLDVAGRDVTRHLIDLLSRRGYAFNRTADFETVRQIKEKLCYVSYDLDLDTKLARETTALVESYELPDGRTIKVGQERFEAPECLFQPGLVDVEQPGVGELLFNTVQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWFSRVLHNDPSRLDKFKVRIEDPPRRKHMVFIGGAVLASIMADKDHMWLSKQEWQESGPSAMTKFGPR
What is the function of this protein?
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the pointed end of the daughter actin filament (By similarity).
What are the official names of this protein?
Actin-related protein 2, Actin-like protein ARP2, Actin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: M1_I81A4
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: PLSY_BORA1
Sequence: MILTEPSPLFAALLIVLAYLIGCVPFAVVVSKLMGLKDPRSYGSKNPGATNVLRTGNKTAAALTLLGDAAKGWFALWLALKLAPGLSSLGYGLVLIAVFLGHLYPVSLGFKGGKGVATALGVLFAVSPWLALATVATWLLVAVVTRYSSLAALVAAFLAPVYYFFGGGTIWPLNAPTAAALVGVSALLFYRHSANIDRLIKGKESRIGSKKA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL35_RALPJ
Sequence: MPKMKTKKSASKRFTARPGGTIKRGQAFKRHILTKKTTKNKRHLRGTEGVHETNLKSVRAMMPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ATPB_STRA5
Sequence: MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKNGDKSQKVVLEVALELGDGLVRTIAMESTDGLTRGLEVLDTGRAISVPVGKDTLGRVFNVLGDAIDLEEPFAEDAERQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALTPEIVGDEHYEVATEVQRVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAETFTGQPGSYVPVEETVRGFKEILDGKHDQIPEDAFRMVGGIEDVIAKAEKMNY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NRDR_VARPS
Sequence: MKCPFCGHLETQVVETRVSEDADFVRRRRQCSACDKRFTTYERPDVNFPVVVKKDGSRADFESGKVRASMMLALRKRPVSIEQIDNALLRIEQKLLASGLREIDSTKVGELVMRELKKLDKVAYVRFASVYRSFEDVDEFRQLLRDI
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: TFB1A_ARATH
Sequence: MAGGQIEKLVKYKSTVKDPGTPGFLRIREGMLLFVPNDPKSDSKLKVLTQNIKSQKYTKEGSNKPPWLNLTNKQAKSHIFEFENYPDMHACRDFITKALAKCELEPNKSVVSTSSEQLSIKELELRFKLLRENSELQRLHKQFVESKVLTEDEFWATRKKLLGKDSIRKSKQQLGLKSMMVSGIKPSTDGRTNRVTFNLTPEIIFQIFAEKPAVRQAFINYVPSKMTEKDFWTKYFRAEYLYSTKNTAVAAAEAAEDEELAVFLKPDEILARETRHKIRRVDPTLDMEADQGDDYTHLMDHGIQRDGTMDVVEPQNDQFKRSLLQDLNRHAAVVLEGRSIDVESEDTRIVAEALTRVKQVSKADGETTKDANQERLERMSRVAGMEDLQAPQNFPLAPLSIKDPRDYFESQQGNVLNVPRGAKGLKRNVHEAYGLLKESILEIRATGLSDPLIKPEVSFEVFSSLTRTIATAKNINGKNPRESFLDRLPKSTKDEVLHHWTSIQELLKHFWSSYPITTTYLHTKVGKLKDAMSNTYSKLEAMKESVQSDLRHQVSLLVRPMQQALDAAFHHYEVDLQRRTAKSGERPNGYV
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit TFB1-1, AtTFB1-1, TFIIH subunit TFB1-1, RNA polymerase II transcription factor B subunit 1-1.
What is the protein family that this protein belongs to?
Belongs to the TFB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADEC_ECOL6
Sequence: MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGIISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIDRQPVSASDFALQFTPGKRYRVIEVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: CYSI_SHEHH
Sequence: MSEQKLAVNEYLKTDSDYLRGTIQQGLNTAVTGAFSEGDQQLIKFHGFYQQDDRDLRNERKEQKLEPLYSFMLRARVAGGVCSPEQWLAVDKIASNLTSANSIRLTTRQTFQYHGIPKRNLKTIIQDLDREALDSIAACGDVNRNVMCNPNPVESKLHQQAYAYAKQLSDNMLPHTKAYAEIWLDNEKLVTTEGEEVEPVYGQTYLPRKFKMAVAVPPDNDVDVYTNDLGFIAVAEGDELVGFNMVAGGGMGSTHGEVSTFPRLADDFGYIKAEDSLKFAEAVMTIQRDWGNRENRKLSRLKYTIVKHGFETFKAEIEARTGIKFEPRRDVVIGDRGDRYGWKQGVDDNWHLTLFIEGGRVKDLPGQPLQTGLREIAKIHRGDFRMTSNQNMIIAGVASADKEQIEGLARQYGLLGKLITETRGHSIACVALPTCALAMAEAERYFPDFLTKVEALQQKHGFLDQGIVIRMTGCPNGCARPFAAEIGLVGKAPGRYNLYLGASFEGTRLNKLYRENIQEAEILDQLDTLFAQYASQRQAGETFGNYTVRSGVVAAVNDAAKDFHG
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RL28_STAEQ
Sequence: MGKQCFVTGRKASTGNHRSHALNANKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RL18_ECOL6
Sequence: MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL29_ECOBW
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL36_ACIB3
Sequence: MKVQASVKKICGSCKVIRRNGVIRVICSAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ISPE_MYCVP
Sequence: MSARDGNTASEWVPTGSVTVRVPGKVNLYLDVGDRRDDGYHELTTVFHAVSLLDEVTVRTADILSLEMTGEGAESLPTDERNLAWRAAELMADHVGRSPDVAISIEKTIPVAGGMAGGSADAAAVLVAMNSLWELGVPRRDLHALAAQLGSDVPFALHGGTALGTGRGEELATVLTRNTFHWVLAFSPGGLSTAKVFAEIDRLRAEEDRTLPPRLESPEPVLAALASGDPAQLAPLLGNDLQPAALSLDSTLRRTLRAGVDAGALAGVVSGSGPTCAFLCGSAGAAVDVGTELAGAGVCRTVRVASGPVQGARVVPSPSNAG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: NXPE3_HUMAN
Sequence: MWTNFFKLRLFCCLLAVLMVVVLVINVTQVEYLDHETVSATFIDSSGQFVSSQVTGISRNPYCGYDQQTLSSQERMEEDSLLAALHRQVPDVGPVPFVKSTDPSSSYFVILNSAAFFKVGSQLEVLVHVQDFQRKPKKYGGDYLQARIHSLKLQAGAVGRVVDYQNGFYKVFFTLLWPGKVKVSVSLVHPSEGIRVLQRLQEDKPDRVYFKSLFRSGRISETTECNVCLPGNLPLCNFTDLYTGEPWFCFKPKKLPCSSRITHFKGGYLKGLLTAAESAFFQSGVNIKMPVNSSGPDWVTVIPRRIKETNSLELSQGSGTFPSGYYYKDQWRPRKFKMRQFNDPDNITECLQRKVVHLFGDSTIRQWFEYLTTFVPDLVEFNLGSPKNVGPFLAVDQKHNILLKYRCHGPPIRFTTVFSNELHYVANELNGIVGGKNTVVAIAVWSHFSTFPLEVYIRRLRNIRRAVVRLLDRSPKTVVVIRTANAQELGPEVSLFNSDWYNFQLDTILRRMFSGVGVYLVDAWEMTLAHYLPHKLHPDEVIVKNQLDMFLSFVCPLET
What are the official names of this protein?
NXPE family member 3, Protein FAM55C.
What is the protein family that this protein belongs to?
Belongs to the NXPE family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAO1_ESCF3
Sequence: MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: HXT16_YEAST
Sequence: MASEQSSPEINADNLNSSAADVHVQPPGEKEWSDGFYDKEVINGNTPDAPKRGFLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKIDKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEETQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN
What is the function of this protein?
Probable glucose transporter.
What are the official names of this protein?
Hexose transporter HXT16.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MBB1A_DANRE
Sequence: MVAVMQTDMGETENSAVRPKVTDAKGILKQNRQFLDYFWDIAKPDRQIRLKAIEDLINYLKNSEQADELKYTLKRLVDGLSHTREDARSGYSVALAQLLSVFEEISLKSTLNSVKEKHNLLTASKKLIRNAVFGNFFGVLALSQSTRLHKEPQVMLECVQLLQSLSEYREHLRDLPRKTMVDILSETSQDVFEEVLFSALQSDLTSALKSPEQLELLLVALQKFPSVLKPKKLKKLLGTTAVITKQNMPRLVEVLKTAARSVKKENILPAVALDLLQVSLREDNFEMFWTDAIITGMMSEMPGPTHYLSFRLLGASLPLLSIPQLQFVLSGDVMRQYGEHTMSAQMPDRFKFAPEMAGYVGEFMQSCTDPDKQLVVVLGFTQLTNQGNPVVPSYWKALENMHPSAVQRYVDWLIEAFCKPQLENCLDFSTRRQKGNQEAAVESESCVSRFRKWIIPRLTFIVENQQIKKQEALVMKVVRFIFFHAFFEVKKPTSEIPETTQALSVPINQQTRTAVVSGFYSLLQALNSMMVLGESVEVQGLNFRRIVGVQADGSMWIYSVFQFASMLLNQNKYVKSLQSFSPEQRQGWDSVLESVEALRKKAKTASSPEHTAFQQLFLLIGIQMFTSPEESLDLLKDLQTCMEKAQAKKSKKKKATDEPHWVEVIVEILLSLVSQPSRLVRSVCKTVFGRICPHLTQAALSSILNVLDPNKDEDESGVVVTDDKKRKLKEEDEDDDDEEEDDDNDEGDDDDDDDDEEEGGEEGEESSDSSDDEEEDEAMEEGQEVDQNFRLELMKVLQGQNALATEEDGSDDEELDDAAMMKLDGSLASLFLEQRKKIQAKKDEKDRLNKEKGLVRDFKIKVLDMVEVFLSKQGFSPLVLGMVEPLLSVIENGMSSESSQPEQDYLRRVADIFRNRLCRGKFYCKEIDGREAELHEMLERLIGRAQKLTDSSVALYYFSAALYVLKVLRGSVVDQELSTMGKVEVERATTCLKNALTSFMTKRKSPLTGAMFIDLFHRFPVLCVNLMDTALENITAGLRDHQQGQACFIMLKALQCKHVKNLMTGEQTTELYKKVVDQLTKSLENVQCKNKTAHDKVVKALELCLHVVKIVLNQKMRVNLELLQDVLASMNAEGCLEKTGKLEDTYWSVMRLFGVIKPKMEKVKKVPEAEQTEETTKKKKGFLPETKKRKNRKKPTILEGKETETPVEKTPEGASGEGKKNKNKKKNKKRKQQAGEETQDQPTPKKAKMQQQQQQKQKKKKKKKGADGE
What is the function of this protein?
May activate or repress transcription via interactions with sequence specific DNA-binding proteins.  May play a role in the repression of the circadian clock gene expression.
What are the official names of this protein?
Myb-binding protein 1A-like protein.
What is the protein family that this protein belongs to?
Belongs to the MYBBP1A family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MU153_SCHPO
Sequence: MGSPSLTKTINASLSLHSITQPITLLKTMHYVLQLTILPSAMQHYATLRNFTHPACSVNKQAEQGKEQQQYAMKSQFQFRSGICSKVRSDELGFKGNSLQLNDLPKNPY
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 153 protein.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YCIB_YERPG
Sequence: MKQLLDFLPLVVFFIFYKMYDIFVASGALIVATLVALAFTWLKYRKVEKMTLVTAAMVLVFGTLTLAFHSDLFIKWKVTVLYVLFALALLVSQWVMKKPLIQRMLGKELTLPDKVWSTLNLSWAIFFLVCGLLNIYVAFWLPQDIWVNFKVFGLTALTLIFTLISGVYIYRHMPEEQKKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARX_MOUSE
Sequence: MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQEKAMQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAGAVAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELSGPGGVAHPEERLSAASGPGSAPAAGGGTGAEDDEEELLEDEEDEEEEEELLEDDDEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC
What is the function of this protein?
Transcription factor (By similarity).  Binds to specific sequence motif 5'-TAATTA-3' in regulatory elements of target genes, such as histone demethylase KDM5C (By similarity).  Positively modulates transcription of KDM5C (PubMed:31691806).  Activates expression of KDM5C synergistically with histone lysine demethylase PHF8 and perhaps in competition with transcription regulator ZNF711; synergy may be related to enrichment of histone H3K4me3 in regulatory elements (By similarity).  Required for normal brain development (PubMed:12379852).  Plays a role in neuronal proliferation, interneuronal migration and differentiation in the embryonic forebrain (PubMed:12379852, PubMed:31691806).  May also be involved in axonal guidance in the floor plate (PubMed:9256348).
What are the official names of this protein?
Homeobox protein ARX, Aristaless-related homeobox.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMG_NEIMF
Sequence: MERKERLRAGIAAMGLDISETAQDRLLAYVDLLKKWNKTYNLTALRDEEKMIVHHLLDSLTLLPHIEGVQTMLDVGSGGGQPGIPAAVCRPDVQITLLDANTKKTAFLQQAVIELGLDNVRVVSGRVEAVSDVRADVVTSRAFAELADFVSWTGHLLKDGGYWAAMKGVYPQGEIGRLPQDVCVEKVQRLDVPGLDAERHIVILSKR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN729_HUMAN
Sequence: MPGAPGSLEMGPLTFRDVTIEFSLEEWQCLDTVQQNLYRDVMLENYRNLVFLGMAVFKPDLITCLKQGKEPWNMKRHEMVTKPPVMRSHFTQDLWPDQSTKDSFQEVILRTYARCGHKNLRLRKDCKSANEGKMHKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEECGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECAKAF
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 729.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNAS6_GORGO
Sequence: MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMIGINNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCRYSAAAQYKFFIVACDPPQKSDPPYKLVPVHLDSIL
What is the function of this protein?
Ribonuclease which shows a preference for the pyrimidines uridine and cytosine.  Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P. aeruginosa, A. baumanii, M. luteus, S. aureus, E. faecalis, E. faecium, S. saprophyticus and E. coli.  Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria.  Probably contributes to urinary tract sterility.  Bactericidal activity is independent of RNase activity.
What are the official names of this protein?
Ribonuclease K6, RNase K6.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted. Lysosome. Cytoplasmic granule.
Protein: GOLS2_AJURE
Sequence: VGLAKGLRKVGTIYPLVVAVLPDVPPEHRRILVEQGCVVREIEPVYPPENHTEFAMAYYVINYSKLRIWEFVEYSKMIYLDGDIQVFENIDHLFDLENGYFYAVMDCFCEKTWSHTPQYQIGYCQQSPKRVHWPKQLGPKPPLYFNAGMFVYEPSLPTYHDLLHTLKITPPTPFAEQDFLNMFLRDVYRPIPNVYNLVLAMLWRHPENVNLEAVKVVHYCAAGSKPWRYTGEEENMDRNDIKMLVNKWRDIYDDEMLDYNAVADPAADGLQLTAVLTEAAGVVRFIPAPSAA
What is the function of this protein?
May promote plant stress tolerance (By similarity).  Galactinol synthase mainly involved in the biosynthesis of transport raffinose family oligosaccharides (RFOs) that function as osmoprotectants.
What are the official names of this protein?
Galactinol synthase 2, ArGolS2, GolS-2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family. Galactosyltransferase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_CLONN
Sequence: MTREEMIQAIKEMSVLELNELVKACEEEFGVSAAAPVAVAGVAGAVGAAEEKSEFDVVLANAGSQKIKVIKAVRELTGLGLKEAKEIVDGAPKTLKEGVAKEAAEEMKAKLEEVGATIELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PSRP_XANOM
Sequence: MSTIRPVFYVSDGTGITAETIGHSLLTQFSGFNFVTDRMSFIDDAEKARDAAMRVRAAGERYQVRPVVVNSCVDPQLSMILAESGALMLDVFAPFIEPLERELNAPRHSRVGRAHGMVDFETYHRRINAMNFALSHDDGIALNYDEADVILVAVSRAGKTPTCIYLALHYGIRAANYPLTDEDLENERLPPRLRNYRSKLFGLTIDPERLQQIRQERRANSRYSAAETCRREVAIAERMFQMERIPSLSTTNTSIEEISSKVLSTLGLQREMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: LFTR_PARXL
Sequence: MVPWLGPDDPFPPVERALGANSGAPGLLAASGDLLPSRLIDAYRRGIFPWYSDGQPVLWWSPDPRMILRPAEFKVSPSLRKTLRRVLRDDAWEIRVDHDFAAVMRACAQAPRRGQRGTWITADVVEAYSSLHRVGDAHSIETWFEGRRVGGLYGVSFGKMFFGESMFAEVTDASKMALAALVGHLRRHEIEMIDCQQNTSHLASLGGREIARKAFIAHVRASVEAPPIPWLFDKTVLLEIVAPAA
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.