PharMolix/UniProtQA huggingface dataset:
Protein: IF1_GEOKA
Sequence: MAKDDVIEVEGTVIETLPNAMFRVELENGHTVLAHVSGKIRMHFIRILPGDRVTVELSPYDLTRGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_ECOK1
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLIKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SALHS
Sequence: MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIERAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: COX2_CANLA
Sequence: MAYPFQLGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMAMRPGLYYGQCSEICGSNHSFMPIVLEMVPLSYFETWSALMV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARAB_ECO24
Sequence: MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDTTGSTPAPIDANGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: SFRP4_RAT
Sequence: MLLSILVALCLCVRLALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSSVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDRGVCISPEAIVTDLPEDVKWIDITPDMMVQERSFDADCKHLSPDRCKCKKVKPTLATYLSKNYSYVIHAKIKAVQRSGCNEVTTVVDVKEIFKSSSPIPRTQVPLITNSSCQCPHILPHQDVLIMCYERRSRMMLLENCLVEKWRDQLSRRSTQWEERLQEQQRTTQDKKQIASRTSRSNPPKPKGRSPASKPASPKKNIKARSAPKKSNPKKSTS
What is the function of this protein?
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts.  They have a role in regulating cell growth and differentiation in specific cell types (By similarity).  SFRP4 plays a role in bone morphogenesis (By similarity).  May also act as a regulator of adult uterine morphology and function (PubMed:12063187).  May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (PubMed:12960062).  Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (By similarity).
What are the official names of this protein?
Secreted frizzled-related protein 4, sFRP-4, DDC-4 protein.
What is the protein family that this protein belongs to?
Belongs to the secreted frizzled-related protein (sFRP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HFQ_WIGBR
Sequence: MAKGQSLQDPFLNTLRRERIPVSIYLVNGIKLQGYIESFDQFVILLKNSISQMIYKHAISTVVPNHTNNQEHNQSQYNNNNACISKP
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: Y331_METJA
Sequence: MDYKQWVREFKKELAHEIEKELVAEVDDNIQRGFQKKELKWKPLSKDYQKRKEKEGRNTKGLIYHGALLKATDSKVKITSKGLQVKVFNNMVYAGVHEFGSKKKNIPARPFIQPALKKVQKDLPKIVEKVIKRMR
What are the official names of this protein?
Uncharacterized protein MJ0331.
Protein: Y177_KLEP7
Sequence: MYDNLKSLGITNPDEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYVIDELDQICQRDRTEIDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein KPN78578_01770.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: RK5_GUITH
Sequence: MNKSLKEIYYQDVIPGLIEQFNYTNIHQVLKITKITLNRGLGEASKNNKILEASIKEFELISGQHPLINKARKSVAGFKIREGMPVGISVTLRKKLMYTFLEKLIHLSLPRIRDFRGVSVKSFDGRGNYNLGIKEQLIFPEIEYDQVDQVRGLDISITTTAKTQQEGIALLRALGMPFNDN
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CBID_PSEF5
Sequence: MREETAEQPAPLRSGLTTGSCATATSLAAARLLLEGSNADAVQIILPKGKQVQMRLEFCRHTADGAEAGTIKDAGDDPDVTHGALLYSRVRLTPEPGIRFIAGQGVGTVTRPGLVLAVGEPAINPIPRRMIGEHLQRLAEERAYPGGFEVTVNVEGGAELALKTMNPRLGILGGLSILGTSGIVRPFSCAAYIASIHQGIDVAKTNGYLHIAACTGNASEDTMRRVYELPEIALIEMGDFVGAVLKHLRKVPVDKLSLCGGFGKISKLAAGHMDLHSRHSSIDLSQLAQWAADAGADPALQQAIRQANTSQQALAMASAAGVALGDAVCRHALDFARSVVPPQVQVEVFAIDRQGGIVGHAGGFQ
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: SYR_PROMM
Sequence: MQAHFASEFMLSLAHALESQLRAAIDRAFPEAAASARESGTGLDPQLAPASKPEFGDFQANAALPLAKPLKQPPRQIAAAIVDQLMVDTAFTAICLTPEIAGPGFINLTVRPECLAAEVQARLADARLGVPLVEGDNDGQQPTPVVVDFSSPNIAKEMHVGHLRSTIIGDSLARVLEFRGHPVLRLNHVGDWGTQFGMLITHLKQVAPEALETADAVDLGDLVVFYRQAKQRFDDDEAFQTTSREEVVKLQGGDPISLKAWSLLCDQSRREFQKIYDRLDVRLNERGESFYNAYLESVVEDLNVSGLLVSDDGAQCVFLEGVTGKDGKPLPVIVQKSDGGFNYATTDLAAMRYRFAAPPQGDGARRVIYVTDAGQANHFAGVFQVAQRAGWIPDAGRLQHVPFGLVQGEDGKKLKTRAGDTVRLRELLDEAVERAESDLRRRLQEEGRDEDESFIEQVATTVGLAAVKYADLSQNRITNYQFSFDRMLALQGNTAPYLLYAVVRIAGIARKGGDLDVTTAELQFSETQEWALVRELLKFDAVIAEVEEELLPNRLCTYLFELSQVFNRFYDQVPVLKAEQPSRSCRLALCRLTADTLKLGLSLLGIPTLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_CITK8
Sequence: MSAVEQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPVNVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKAVPEDFHARFSATARRYRYIIYNHRLRPAILGHGVTHFYEPLDAERMHRAAQCLIGENDFTSFRAVQCQSRTPWRNVMHINVTRHGAYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRRLSAATAKAEGLYLVAVDYPERFDLPKTPLGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TGB3_P1AMV
Sequence: MHYPTEADTSTGPNPSATSAPVRPRHVTPSLSPSSSSSPSPDSFYYFLAAAVILTAALAAALLTPNPGCTIVITGHTTIIQGSCPIPPQLVLAAHPRGLSLEQYLKFTNTLPDGSQHRSHR
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata.  May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity).
What are the official names of this protein?
Movement protein TGBp3, 13 kDa protein, Triple gene block 3 protein, TGBp3.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: ARNC_SALG2
Sequence: MFDAAPIKKVSVVIPVYNEQESLPELIRRTTAACESLGKAWEILLIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQHAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYGCMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLGSVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTPFTEESHQ
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y4530_RHOPA
Sequence: MSNPEPDDSNNRIVAVTLDEESIGRSGPDIEHERAIAIYDLVEKNLFAPEGAGEGPFTLHIGITGNRLMFDIRREDGAPVITHLLSLTPFRRIVKDYFMICDSYYQAIRTATPDKIEAIDMGRRGIHDEGSRTLQERLAGKVRIDFETARRLFTLISVLHWKG
What are the official names of this protein?
UPF0262 protein RPA4530.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: Y3815_MYCBO
Sequence: MRILAMTRAHNAGRTLAATLDSLAVFSDDIYVIDDRSTDDTAEILANHPAVTNVVRARPDLPPTPWLIPESAGLELLYRMADFCRPDWVMMVDADWLVETDIDLRAVLARTPDDIVALMCPMVSRWDDPEYPDLIPVMGTAEALRGPLWRWYPGLRAGGKLMHNPHWPANITDHGRIGQLPGVRLVHSGWSTLAERILRVEHYLRLDPDYRFNFGVAYDRSLLFGYALDEVDLLKADYRRRIRGDFDPLEPGGRLPIDREPRAIGRGYGPHAGGFHPGVDFATDPGTPVYAVASGAVSAIDEVDGLVSLTIARCELDVVYVFRPGDEGRLVLGDRIAAGAQLGTIGAQGESADGYLHFEVRTQDGHVNPVRYLANMGLRPWPPPGRLRAVSGSYPPATPCTITAEDR
What are the official names of this protein?
Uncharacterized protein Mb3815c.
Protein: GSH1_SHIBS
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTQATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCCDISGTDAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGKAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMETADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: EFP_GLOVI
Sequence: MISSNDFRTGTTIELDGQVWRVIEFLHVKPGKGSAFVRTKLKNVMTGNVNERTFRAGETLPQAVVEKRDMQFVYPQGDNEYVFMDMESYEQEALTRETLGDGAKYLKEGMSVSILKWQERVIGVDLPNTVVLQVVETDPGVKGDTAQGGTKPAKVETGAEVMVPLFITIGEKIKIDTRDNSYLGREN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAI_LOTJA
Sequence: MTNLPSIFVPLVGLVFPAMAMASLFLYLQKNKIF
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PEPB_ECOLC
Sequence: MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVEWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPEMIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLASAAQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRGA_MYCSK
Sequence: MPKSKVRKKNDFTISPVSRTPVKVKAGPSSVWFVALFVGLMLIGLIWLLVFQLAATNPVDAPGMLQWMADLGPWNYAIAFAFMITGLLLTMRWR
What is the function of this protein?
Involved in cell division.
What are the official names of this protein?
Cell division protein CrgA.
What is the protein family that this protein belongs to?
Belongs to the CrgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL37_NITMS
Sequence: MVKGTTSMGGFTKKKVHIRCRRCGKNSLHKRHHQCASCGFPEAKRRKYSWIKWYT
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: UPPP_BURM7
Sequence: MDWILICKALALGIVEGLTEFLPVSSTGHLIVAGSFLRFHPEQAKTFDVVIQFGAILAVCWEYRRRIIDVVTGLPAQREARRFTMNVVIATVPAVALALLFEKTIKSVLFAPVPVAVALVVGGAAILWVEGRQRERSEPARVQSIDALTPFDALKVGLAQCCALIPGMSRSGSTIIGGMLFGLERRVATEFSFFLAIPVIFGATLYETAKDWRAFNVDSVGLFAIGLVAAFVSAFACVRWLLRYVASHDFTAFAWYRIAFGLFVLLVGYSGWIEWT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANB_SHEON
Sequence: MSKVTSSTLLKYKQEGRKFTALTAYDASFASAFDGEGIDVLLVGDSLGMVLQGHDDTLPVTTADIAYHTRCVRRGIERSLLIADMPFMSYATPEQAMENATTLMQAGANMVKLEGGHWLLETVTKLTERGIPVCAHLGLTPQSVNVFGGFKVQGRDAENAQRIIDEAKALEAAGAQLLVVECIPASLATAITQALTIPVIGIGAGATTDGQILVMHDVLGISSGYIPRFSKNYLKQTGEIRSAVRAYIEEVANGSFPSAEHTFN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLRA2_MOUSE
Sequence: MSEQEVTYTTLRFHKSSGLQNPVRPEETQRPRDVGHRECSVPWKFIVIVLGILCFLLLLTVAVLVIHIFRDGQEKHEQEKTLNNLRQEYQVMKNDSSLMEEMLRNKSSECKALNDSLHYLNREQNRCLRKTKIVLDCSQNKGKQVEGYWFCCGMKCYYFIMDDKKWNGCKQICQDYNLTLLKTNDEDELKFLKSQLQRNTYWISLTHHKSKEESQQIGDRPSKLDSAARNSVPNRQKCAYLSSFSTEEDDCARTHGCICEKRLNKFPIPGSCAKGRTQSALQRDEDES
What is the function of this protein?
Receptor on natural killer (NK) cells for class I MHC.
What are the official names of this protein?
Killer cell lectin-like receptor 2, Lymphocyte antigen 49b, Ly-49b, T-cell surface glycoprotein Ly-49B.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: CBPC2_HUMAN
Sequence: MFPALETHLKQTIPDPYEDFMYRHLQYYGYFKAQRGSLPNSATHQHVRKNNPQCLLNGSLGEKDDLIPDTLQKEKLLWPISLSSAVHRQIEAINRDFHSCLGWMQWRGLSSLQPPPPRFKDSPASAFRVAGITDSHMLSLPHLRSRQLLYDELDEVNPRLREPQELFSILSTKRPLQAPRWPIECEVIKENIHHIEWAPPQPEYFYQPKGNEKVPEIVGEKKGTVVYQLDSVPIEGSYFTSSRVGGKRGIVKELAVTLQGPEDNTLLFESRFESGNLQKAVRVDTYEYELTLRTDLYTNKHTQWFYFRVQNTRKDATYRFTIVNLLKPKSLYTVGMKPLLYSQLDANTRNIGWRREGNEIKYYKNNTDDGQQPFYCLTWTIQFPYDQDTCFFAHFYPYTYTDLQCYLLSVANNPIQSQFCKLQTLCRSLAGNTVYLLTITNPSQTPQEAAAKKAVVLSARVHPGESNGSWVMKGFLDFILSNSPDAQLLRDIFVFKVLPMLNPDGVIVGNYRCSLAGRDLNRHYKTILKESFPCIWYTRNMIKRLLEEREVLLYCDFHGHSRKNNIFLYGCNNNNRKYWLHERVFPLMLCKNAPDKFSFHSCNFKVQKCKEGTGRVVMWRMGILNSYTMESTFGGSTLGNKRDTHFTIEDLKSLGYHVCDTLLDFCDPDQMKFTQCLAELKELLRQEIHKKFHELGQDVDLEGSWSDISLSDIESSTSGSDSSLSDGLPVHLANIADELTQKKKMFKKKKKKSLQTRKQRNEQYQKKNLMQKLKLTEDTSEKAGFASTLQKQPTFFKNSENSSFLPMKNENPRLNETNLNRRDKDTPLDPSMATLILPKNKGRMQNKKPGFTVSCSPKRTINSSQEPAPGMKPNWPRSRYPATKRGCAAMAAYPSLHIYTYP
What is the function of this protein?
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins.  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein.  Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate.  Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK.
What are the official names of this protein?
Cytosolic carboxypeptidase 2, ATP/GTP-binding protein-like 2, Protein deglutamylase CCP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Colocalizes with gamma-tubulin in the centrioles and with glutamylated tubulin in the basal bodies of ciliated cells.
Protein: CP1A1_PLAFE
Sequence: MMLMMLPFIGSVSVSESLVAMTTMCLVYLILKFFQTEIPEGLLRLPGPKPLPIIGNVLGLGSKPYLSLTDMSKRYGHVFQIQIGMRPVVVLSGSETVRQALIKQGDDFAGRPDLYSFRFINAGKSLAFSTDQAGVWRARRKLAYSALRSFSNLEGTTPEYSCVLEEHICKEGEYLIKQLNTVMKADGSFDPFRHIVVSVANVICGMCFGRRYDHDDQELVGLVTLSDEFGRVVGSGNPADFIPILQYLPSAAMKNFLRINSRFTEFVQKIVTEHYTTFDKDNIRDITDSLIDHCEDRKLDENSNVQMSDEKIVGIVNDLFGAGFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGLDRMPLLSDKPNLPFLEAFILEILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPELWKDPSSFNPDRFLSADGSEVNKLDGEKVMAFGMGKRRCIGEVIARNEVYLFLAIIIQKLHFLPIPGEKLDMTPEYGLTMKHKRCHLKATMRARNEH
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: NDK_NOCSJ
Sequence: MSLRTLVLLKPDAVRRGLVGAILSRYEAKGLTIVAMEQRTIDAAVADQHYAEHVAKEFYPPLRDFVTGGPLVALVLEGDNSVDVVRLLNGATDGSKAAPGTIRGDFSLSNRENLVHGSDSPESAEREIGIWFPGL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_STAAN
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PROA_LACPL
Sequence: MVDLEQLGQQAQQASYTLGLLSTAQKNQVLTAMATALTSHQDEILAANAQDLENPQVPVKFVDRLRLTADRIQDMAIGLKQVVSLPDPIGNVDRAWRNEAGLMIAKERVPLGVIGMIFEARPNVTVDASALCFKTGNAVILRGGKEALHSNQALVQVLRGALRAEAVDENAIQLITDTSHATAAKFMQLTDYVDVLIPRGSARLIQTVLAKATVPVIETGAGNCHVYVDKDAQLQMATDIVINGKVQRPSVCNATEKLLIHREVAADYLPSMIQALREQGVEVRGDAATQAIVPDVVPATDADWGTEYNDLIIAVKVVDSEAAAITHINRYNTQHSEAIVTDNYQAGKLFQQRVNAACVYINASTRFTDGFEFGFGAEIGISTQKLHARGPMGLAELTSYKYVIDGNGQIRH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CHRSD
Sequence: MKLNNLSPAPGSKHAEKRVGRGIGSGLGKTGGRGHKGQKSRSGGSVKPGFEGGQMPLQRRLPKYGFTSAKSLVSEEVRLAELAKVDGEIVDLESLKKANVLKDNTQYAKVILSGELNKAVTVRGLKVTKGARDAIAAAGGKVED
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.