PharMolix/UniProtQA huggingface dataset:
Protein: DNAA_BURCM
Sequence: MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDASANTLSIAAPNRFKLDWVKSQFSGRISDLARDFWNAPIEVQFVLDPKAGMRSAAAHAAPAAQRAPLTPNGPAATVAAIAANLAANAGAAPSAPADVPMTASAAAAHHLNADDADIDLPSLPAHEAAAGRRTWRPGPGAAPANGGEADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLYGGVGLGKTHLIHAIGNQLLLDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEGVNLSEDVAFFVAKHLRSNVRELEGALRKILAYSKFHGREISIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_SHESH
Sequence: MSSKQEPVVLGKLGSSHGIKGWLKITTYTDSVEGIFDYSPWLIKEQGEWREVKVLQWRFQGKAVVACLEGVETREHAQMLTNCEIAVTPEQMDTLPEDEFYWRDLIGCEVMNTKGYNMGKVQEIVETGSNDVLLVKANAKDGFGKAERMIPFVTEQFIIEVNLTEKQITVDWDPDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_MYCA1
Sequence: MNPINYLYLSALLFTIGAAGVLLRRNAIVMFMCVELMLNAVNLAFVTFARMHGHLDGQMIAFFTMVVAACEVVIGLAIIMTIFRTRKSASVDDANLLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS9_ECOK1
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: GCSH_RHILO
Sequence: MNLMAKTYFTSDHEWLRVEGGIATVGITDYAQEQLGDLVFVELPETGKKLTKGDTAVVVESVKAASDVYAPVDGEITEANGTLSSDPSLVNSAATGAGWLWKMRLADESQLAGLMDEAAYKAHIA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: STF2_YEAST
Sequence: MTRTNKWTEREGKADPKYFSHTGNYGESPNHIKKQGSGKGNWGKPGDEIDDLIDNGEIPPVFKKDRRGSNLQSHEQKFENVQKE
What is the function of this protein?
This is one of two stabilizing factors of the inactive mitochondrial F0F1-ATPase.  It binds to the F0 part and facilitates the binding of both the inhibitor and the 9 kDa protein to F1.
What are the official names of this protein?
ATPase-stabilizing factor 15 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the STF2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PCSK9_MACNE
Sequence: MGTVSSRRSWWPLPLPLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPKGGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVARCAQDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCSALPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSEEAVAAVAICCRSRHLVQASQELQ
What is the function of this protein?
Crucial player in the regulation of plasma cholesterol homeostasis.  Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments.  Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway.  May prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation.  Can induce ubiquitination of LDLR leading to its subsequent degradation.  Inhibits intracellular degradation of APOB via the autophagosome/lysosome pathway in a LDLR-independent manner.  Involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway.  Inhibits epithelial Na(+) channel (ENaC)-mediated Na(+) absorption by reducing ENaC surface expression primarily by increasing its proteasomal degradation.  Regulates neuronal apoptosis via modulation of LRP8/APOER2 levels and related anti-apoptotic signaling pathways (By similarity).
What are the official names of this protein?
Proprotein convertase subtilisin/kexin type 9, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Endosome. Lysosome. Cell surface. Endoplasmic reticulum. Golgi apparatus. Note=Autocatalytic cleavage is required to transport it from the endoplasmic reticulum to the Golgi apparatus and for the secretion of the mature protein. Localizes to the endoplasmic reticulum in the absence of LDLR and colocalizes to the cell surface and to the endosomes/lysosomes in the presence of LDLR. The sorting to the cell surface and endosomes is required in order to fully promote LDLR degradation (By similarity).
Protein: FMO1_RAT
Sequence: MVKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSCDLGGLWRFTEHVEEGRASLYNSVVSNSSKEMSCYSDFPFPEDYPNFVPNSLFLEYLQLYATQFNLLRCIYFNTKVCSITKRPDFAVSGQWEVVTVCQGKQSSDTFDAVMVCTGFLTNPHLPLDSFPGIQTFKGQYFHSRQYKHPDVFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPVVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVLIKPSIKEVKENSVVFNNTPKEEPIDVIVFATGYSFAFPFLDESIVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMIPTGETQARWVVQVLKGATTLPPPSVMMKEVNERKKNKHSGFGLCYCKALQSDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVNVTKTRTVQETPSTFETLLKLFSFLALLVAVFFIFL
What is the function of this protein?
Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics (PubMed:8504165).  Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes (By similarity).  In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine (PubMed:8504165).
What are the official names of this protein?
Flavin-containing monooxygenase 1, Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, Hepatic flavin-containing monooxygenase 1, FMO 1, Trimethylamine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: DEF_RHOPS
Sequence: MALREIIILPDKRLREISKPVAEVTPEIRKLADDMFESMYDAPGIGLAAIQIAEPVRLITMDIVRKEGNGKSDPRAFINPEIVGASAEMNVYEEGCLSIPEYYADVERPAVVRIRYTDLDGNVKEEDADGLFATCIQHEIDHLDGVLFVDHLSKLKRAMVVRKFEKAAKRGIKYV
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: KCNH5_RAT
Sequence: MPGGKRGLVAPQNTFLENIVRRSSESSFLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKSSTCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKNRTPVWFYMQIAPIRNEHEKVVLFLCTFKDITLFKQPIEDDSTKGWTKFARLTRALTNSRSVLQQLTPMNKTETVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKTTWDWVILILTFYTAIMVPYNVSFKTKQNNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTIQIDSWLYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVIQDEEVVAILGKGDVFGDIFWKETTLAHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDVKKEEEERLRQKNEVTLSIPVDHPVRKLFQKFKQQKELRNQGSAQSDPERSQLQVESRPLQNGASITGTSVVTVSQITPIQTSLAYVKTSETLKQNNRDAMELKPNGGAEPKCLKVNSPIRMKNGNGKGWLRLKNNMGAHEEKKEEWNNVTKAESMGLLSEDPKGSDSENSVTKNPLRKTDSCDSGITKSDLRLDKAGEARSPLEHSPSQADAKHPFYPIPEQALQTTLQEVKHELKEDIQLLSCRMTALEKQVAEILKLLSEKSVPQTSSPKPQIPLQVPPQIPCQDIFSVSRPESPESDKDEINF
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated potassium channel.  Elicits a non-inactivating outward rectifying current.  Channel properties may be modulated by cAMP and subunit assembly.
What are the official names of this protein?
Potassium voltage-gated channel subfamily H member 5, Ether-a-go-go potassium channel 2, rEAG2, Voltage-gated potassium channel subunit Kv10.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.2/KCNH5 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TREF_ECOLC
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKMIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX21F_TRILK
Sequence: MKPIVSILIFCALAVVIMGHPLDSGYGIPHIVEKLPNGQWCKTPGDDCSKSNECCKPKDPENYSGGCVAQWSGMHGKRINMCRICYLESSMC
What is the function of this protein?
Probable neurotoxin with ion channel impairing activity.
What are the official names of this protein?
Toxin ICK-15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASTE1_MOUSE
Sequence: MGIRGLMSFVEDYSNEFFVDLKLRNTKLIIDGYSLFHRLCFNSDLELRYGGDYDLFADVVQKFFESLFVCHICPYVVLDGGCDISDKKLTTLKDRAKEKIQAARSLSLGGGGNVCPLLIREVFIQVLIRLEVCFVQSFSEADRDIMTLANHWNCPVLSSDSDFCIFDLRSGFCSLNSFQWRNLNTIKDTQDYYIPARSFSLNAFCHYFNNMNKALLPLFAVLCGNDHVNLPIMDTFISKVRLPLSSKGRRYHRVLGLLNWLSHFDDPTEALDNVLKSLPKKSRENVKELLCCSMEEYQQSPVKLQDFFQYGSYVCTDASDLGLPEWVLGALAKGQLPPFISDALVLRRTFLHTQVENMQRPNAHRISQPIRQIIYGLLLNGPSHAEDIAQNTLPSQLLAFNEVERIDTNIKTSTVYAKQLLKDQCDLSKLAELPLARRQMLLLEALKVKQVVLESIPTFLKLPIAVTCYWLQSTEAKAKLHHLQALLLGMLREPLHAIVNSPGTEDPQRGGAKMLYEELCQVKAPMRPGPRVDLDTAHVFCQWQSCLQMGLYLNQLLSTPLPEPNLTWLYNGSLVHRLCQQLPASSSVESLLSLCPEAKQLYEHLFNATKSYAPAELFLPKTKSKSKKKRQKKKVASLGTTADAKHWYDRSNRFGPLMPESLEEHVENSELE
What is the function of this protein?
Possible role in EGF receptor signaling.
What are the official names of this protein?
Protein asteroid homolog 1.
What is the protein family that this protein belongs to?
Belongs to the asteroid family.
Protein: GPDA_CAMJ8
Sequence: MRIAVIGAGKWGSALHLALKENHNCFISSLHQRDLEDFVSIKEALECEYLVFALSSQGMRAWLKENFINKGQKILIASKGIEDQSCQFLDEIFLDFVPKENFCVLSGPSFAAEVMQKLPTALMISGINQELCKKFASFFPDFIKTYIDNDVRGAEICGAYKNVLAIASGISDGLKLGNNARAALISRGLIEMHRFGKFFGAKEETFLGLSGAGDLFLTATSVLSRNYRVGLKLAQNQKLDSILVELNEVAEGVKTAYAIEKLAKMKGIYTPIVNEVVAIFKGKSVQEATQSLLKQND
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKHG4_HUMAN
Sequence: MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEELQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGESDTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCLLAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPRPEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQLPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKAVPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTAMDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEAGEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTEFSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPDLPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCVSQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVPPPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGHTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRHGPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRASIAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALEAEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
What is the function of this protein?
Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi.
What are the official names of this protein?
Puratrophin-1, Pleckstrin homology domain-containing family G member 4, PH domain-containing family G member 4, Purkinje cell atrophy-associated protein 1.
Protein: 3DHQ1_ASPFU
Sequence: MGKSILLINGPNLNLLGTREPHIYGNTTLADVEASCKAHAESLGATLATFQSNHEGAIIDRIQAARGNVDGIIINPGAFTHTSVAIRDALLGVGIPFIELHVSNVHAREPWRHHSYFSDKAAGIIVGLGVYGYKVAVEHVALNFKERAAL
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase 1, cDHQase 1, 3-dehydroquinate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RPOB_RICB8
Sequence: MVSLRDNIEVQPLSHNKRVRKNFGHINLVADIPNLIEIQKNSYEKNFLQLDTKDSERKNKGLQSILNSIFPISDPSNIANLEFVKYEFDTPKYDVEECTQRSLSYDSALKVTLRLSIWDIDEDTGSREIKGIKEQQVYMGNIPLMTKNGTFIINGTERVVVSQMHRSPGVFFYHDEGKVHSSRKLLYSARVIPYRGSWLDLEFDAKDIIYFRIDRKRKLYATTLLKAIGMSTEEIIKFYYDSVNYKVVKNKGWAVKFMPSHITAHRLTSDLIDADTGNVLLKAGQKITPRLAKKYAGEGLNNILVSHEALIGKYLSEDLKDPESDEILAKIGEMITVELLSVISDLKIKNISVLVINPQSGPYIRNTLFSDKNQDRESALFDIFRVLRPGEPANIEAAESLFYNLFFDPERYDLSEVGRIKMNSRLELNISDETTVLTTDDIKNILRVLVELKDRKGIIDDIDHLGNRRVRSVGELIENQFRIGLVRMEKSVVERMSAGDIDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRAGFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRKVKDGHVTDEVVYLSAIEEGKYKIGQANSKVDKDGILQGEFINCRVEGGNFVMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGTGVEGVVAKDSGASVLALNDGIVEQVDSNRIVIRAIGQKTESAPSVDIYNLLKFQKSNHNTCINQKPLVKVGHYVKKNDIIADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDVFTSVHIEEFEVIARDTRLGPEEITRDIPNVSEEALRHLDEVGIIYVGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQRAIAIEKQQIEKLAKDRDDELEIIEHFVFSWLEKLLVGQVSINGPKTVKTGQTITSEILKGLSKGQLWQFTVEDANVMNEIEQLKGHYDGKKEALNKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVISRIVPEEDMPFLEDGTVVDIVLNPLGLPSRMNIGQVLETHLGWASVNLAKKIAGLVEEHKTKHASIEKIKKFLIELYGENINHILEKSDEEIISFCNEAAKGVYFATPVFDGAKVEDVKDMLRLAGQDLSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKIYDSIVRGENNFESGIPESFNVMIKEFRSLCLNVKLEVTS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MNTH_PECCP
Sequence: MPGSRVIESTSRTSRKVKLSLMGPAFIAAIGYIDPGNFATNIQSGAAYGYTLLWVVVWANLMAMLIQLLSAKLGIATGKNLAEHIRDRFPRPAVWAYWVQAEIIAMATDLAEFIGAAIGFKLLLGVSLLEGAILTAIATFLILMLQQRGQKPLEMVIGGLLLFVAAAYIVELVFSQPELSALAKGMAMPSLPTSDAVLLAAGVLGATIMPHVIYLHSSLTQHEGSHTRAERYSATKVDVAIAMTIAGFVNLAMMATAAAAFHFSGNQDIADLDKAYLTLEPLLGKAAAVIFGLSLVAAGLSSTVVGTLAGQVVMQGFVRFHIPLWVRRSVTMLPSFIVILSGMDPTRVLVLSQVVLSFGIALALVPLLSFTGNRELMGTMVNGKWVQRIGQLIVVLVVSLNMYLLIDTMSGI
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEX20_PICPA
Sequence: MFTSNGSCGPATALDNLSKRVGQDRTLENDHVARFRDQNSSQNRAFRAESSFNTTAGAEFGQFQNTSVQRNYFPSAELIRKNTRFGDNWSSEFRQQQENNKWVEDFGAMNLENVRMEQEQSFQTMDQRTNMQAMSSTANAWTQEFNHMQHNKEMEYEMRIRETQRLVNAPAREVFSMVNQHSQQHNQNFTHNQTQLGDQSHYMTNLAFERQFETVQNEIDGMDMFSDSEQVEQQKELQKEDDNNDIETTKFAEIAQQVFNQMNNVDTTVSQNTEHKFKQSNFLRLMDKVAQREVEINGSGDRFIDKTGNDIRDYLPDPLSDLR
What is the function of this protein?
Coreceptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal, such as 3-oxoacyl-CoA thiolase (PubMed:16390998, PubMed:17209040, PubMed:23344950).  Acts via its interaction with PEX7, promoting association between PEX7 bound to cargo proteins and the PEX13-PEX14 docking complex (PubMed:16390998).  PEX20 along with PEX7 and PTS2-containing cargo proteins are tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex (PubMed:17209040, PubMed:23344950).  PEX20 coreceptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle (PubMed:17209040, PubMed:23344950).  Also mediates peroxisomal import of proteins that do not contain PTS1- or PTS2-type peroxisomal targeting signals, such as acyl-CoA oxidases (Aox) izozymes (By similarity).  Import of acyl-CoA oxidases (Aox) izozymes is independent of PEX7 (By similarity).  Required for PEX7 ubiquitination (PubMed:25009284).
What are the official names of this protein?
Peroxisome biogenesis protein 20, Peroxin-20, Pppex20.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
Protein: GLPG_ECOBW
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PERB_ECO11
Sequence: MKNNLREEKEVVFDGCMNVLSLPSGWKAITPKKNNATSEIIVLFIPPKASYHIILKYNKTKHCELFFSDHITGEQDIIYSQNAFFSHVINHTIALVDVLNKKSYASNVIKFLITMEGGGDILSESKRAP
What is the function of this protein?
Positive regulatory protein of bfpA, the gene coding for the bundle-forming pilus of EPEC.
What are the official names of this protein?
Protein PerB, Protein BfpV.
Protein: ISPT2_CORGL
Sequence: MSEFQVPEIPAQFLPKHIALVMDGNGRWATERGMKRTEGHKRGEAVLLDVVDACIELGVPYLSAYAFSTENWRRSTDEVRFLMGFNRDVLRRQRDDLHEKGVRVRWVGRRPRLWRSVIRELETAEELTKDNTTMTLAMCVNYGGRAEIIDAARDIARLAAEGKLRPEQITEKTFPNFLDEPDMPDVDLFLRPSGEKRTSNFLLWQSAYAEMVYQDKLFPDFTQQDLYDAVLEYAKRDRRFGSA
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase 2.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: CT0C_CONTS
Sequence: MLCLPVFIILLLLASPAAPNPLERRIQSDLIRAALEDADMKTEKGILSSIMGTLGKIVGLAP
What are the official names of this protein?
Conotoxin TsMLCL-02.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NSS_SFSV
Sequence: MINNNMMNSQYMFDYPAINIDVRCHRLLSSVSYVAYNKFHTHDVSTYEHCEIPLEKLRLGFGRRNSLADFYSLGELPASWGPACYFSSVKPMMYTFQGMASDLSRFDLTSFSRKGLPNVLKALSWPLGIPDCEIFSICSDRFVRGLQTRDQLMSYILRMGDSHSLDECIVQAHKKILQEARRLGLSDEHYNGYDLFREIGSLVCLRLINAEPFDTASSGEALDVRTVIRSYRASDPSTGLTEYGNSLWTPIHSHVDENDESSSDSDF
What are the official names of this protein?
Non-structural protein NS-S.
What is the protein family that this protein belongs to?
Belongs to the phlebovirus NS-S protein family.
Protein: ZN519_HUMAN
Sequence: MELLTFRDVAIEFSPEEWKCLDPAQQNLYRDVMLENYRNLVSLAVYSYYNQGILPEQGIQDSFKKATLGRYGSCGLENICLWKNWESIGEGEGQKECYNLCSQYLTTSHNKHLTVKGDKEYRIFQKKPQFLSAAPTEPCIPMNKYQHKFLKSVFCNKNQINFNHDSNISKHHSTHFLENYYNCNECEKVFYQSSKLIFPENIHIQKKPYNSNECGETSDPFSKLTQHQRIYIGESSQRCNKKCIIVFSQSHLKGHKIINTGEKSVKYKERGKAFTRGLHLGHQKIHTGEKPYKCKKCDKAFNKSSHLAQHQRIHTGEKPFKCKECGKAFNRGSYLTQHQRIHTGERAFKCEECGKAFNRGSYLTQHQRIHTGEKPFRCKECGKAFNRSSYVTQHQRMHTGEKPFKCKECGKAFNRASHLTQHQRIHTGEKHFKCKECGKAFNRGSHLTRHQRIHTGEKSFKCEECGKAFIWGSHLTQHQRVHTGEKFFKCKECGKAFTRSSHLTQHQRIHTGEKPFKCKECGKAFNRRSTLTQHQIIHTR
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 519.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.