PharMolix/UniProtQA huggingface dataset:
Protein: KDPC_BURO1
Sequence: MKSLIRPLVVLFVVLNAVTGLAYPAVMTVFGQAVFPSQANGSLIEQNGKVVGSALIGQPFDAPKYFWGRLSATAPMPYNAAGSGGSNLGPLNPSLADQVKARIAALRDAGTDLSKPVPVDLVTASASGLDPEITPAAAAYQVERVAKARNLTPDAVAQLVAANTTGRQFGVLGEPRVNVLKLNLALDAAQAAH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
Protein: FLPA_METJA
Sequence: MEDIKIKEIFENIYEVDLGDGLKRIATKSIVKGKKVYDEKIIKIGDEEYRIWNPNKSKLAAAIIKGLKVMPIKRDSKILYLGASAGTTPSHVADIADKGIVYAIEYAPRIMRELLDACAERENIIPILGDANKPQEYANIVEKVDVIYEDVAQPNQAEILIKNAKWFLKKGGYGMIAIKARSIDVTKDPKEIFKEQKEILEAGGFKIVDEVDIEPFEKDHVMFVGIWEGK
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: CC50A_PONAB
Sequence: MAMNYNAKDEVDGGPPCAPGGSAKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTEPSSPCNKCLSPDVTPCICTINFTLEKSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDSSALLNPSKECEPYRRNEDKPIAPCGAIANSMFNDTLELFLIGNDSYPIPIALKKKGIAWWTDKNVKFRNPPGGDNLKERFKGTTKPVNWLKPVYMLDSDPDNNGFINEDFIVWMRTAALPTFRKLYRLIERKSDLHPTLPAGRYSLNVTYNYPVHYFDGRKRMILSTISWMGGKNPFLGIAYIAVGSISFLLGVVLLVINHKYRNSSNTADITI
What is the function of this protein?
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids.  Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules.  The beta subunit may assist in binding of the phospholipid substrate.  Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex.  ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE).  The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane.  Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes.  Involved in uptake of platelet-activating factor (PAF).  Can also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations (By similarity).
What are the official names of this protein?
Cell cycle control protein 50A, P4-ATPase flippase complex beta subunit TMEM30A, Transmembrane protein 30A.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle membrane. Apical cell membrane. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Protein: TXBA_ANDCR
Sequence: DDLHPFNENNMYYGCKGLSNSNKFED
What is the function of this protein?
Binds to sodium channels (Nav) and affects the channel activation process.
What are the official names of this protein?
Toxin b subunit alpha.
What are the subcellular locations of this protein?
Secreted.
Protein: YL120_MIMIV
Sequence: MNSYMTSSDFVEPRSELELNFSSWISENEINRFRDMTLDDNFMNLFFELPDTQKKQLCGRFLLENRKDNIVFIIENITHNNKNILNIILLALIEELEVDNEFDDLFILMINLGLDVTYNDNEAIVHASFFCKLSIITKLIEYGADIHVKNDLPLRLSVQKFEVFKFFVENGADIHVNNDYCIRAAAYLSNYDVMKYLIEFGCDPNIDNGYLLKTIVNSENVFGKMFVASMTQCLDYLFGLGVKADCLGIFELKNCIKKQNFLLLDVLTMNGVDFSVLNQLYENSEVDMCHEVKLINYLVSNGVNYESTVRLVISDMRSFQDNFINGQSPSFTICNTNYQ
What are the official names of this protein?
Putative ankyrin repeat protein L120.
Protein: ICAD_STAAR
Sequence: MVKPRQREYPTLKSSLNIIRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQKGRES
What is the function of this protein?
Necessary for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide.  Is required for full IcaA N-acetylglucosaminyltransferase activity (By similarity).
What are the official names of this protein?
Poly-beta-1,6-N-acetyl-D-glucosamine synthesis protein IcaD, PGA synthesis protein IcaD, Poly-beta-1,6-GlcNAc synthesis protein IcaD, Biofilm polysaccharide intercellular adhesin synthesis protein IcaD, Biofilm PIA synthesis protein IcaD, Intercellular adhesion protein D.
What is the protein family that this protein belongs to?
Belongs to the IcaD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UB2V2_PONAB
Sequence: MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
What is the function of this protein?
Has no ubiquitin ligase activity on its own.  The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.  This type of poly-ubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  Plays a role in the control of progress through the cell cycle and differentiation.  Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage (By similarity).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: GLMM_SHIDS
Sequence: MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVYSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVSAEVEAALGSRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GNTR_PSEAE
Sequence: MSITKNDKNTRTTGRPTLNEVARRAGVSPITASRALRGVASVAEELAQKVRDAARELGYVANPAARALASAQSHSVAVLVPSLANLLFIETLEAIHAVLRPQGLEVLIGNFHYSRNEEEDLIRNYLAYQPRGLLLTGFERTESARRMIEASGIPCVYMMDLDSGSGLNCVGFSQLRAGEAAAEHLLARGRRRLAYIGAQLDQRTLLRGEGFRRALQKAGCYDPGLEILTPRPSSVALGGELFVQLLASQPQVDGVFFCNDDLAQGALLEALRRGVKVPEQIAVLGFNDLPGSDCTVPRLSSIRTPREAIGRRAAEQLLALIAGKEVRDSALDMGFELMAREST
What is the function of this protein?
Involved in the regulation of glucose metabolism.  Represses its own expression as well as that of the gluconate permease GntP (PubMed:28752954).  It employs an effector mediated de-repression mechanism: in the absence of ligand, GntR binds to the gntR and gntP promoters and represses their expression.  The release of promoter bound GntR is induced by gluconate and 6-phosphogluconate that bind with similar apparent affinities to the GntR/DNA complex.  The release of GntR leads to transcription of the genes (PubMed:28752954).
What are the official names of this protein?
HTH-type transcriptional regulator GntR.
Protein: LONP2_CANDC
Sequence: MAKYNNNNYANKATNLKQQVVLPTYTLDSNLVLLPGIMYNVTFSRFKAAALLYRYKNFISQVSIINNLLSEYDFNSGNSNEEERSETEQKIEQSSLGQPETYHEINPSVISTEAVEGIKEFFQYETNMKTGRGGKGEKEAKSTNDGIKEFDWLTLAIIPNLDKIKDPETNYSIGDAAKLTNVVTVARIIGIVDDSTNIKLTLQAITRGVQITDDSKMNQHKNGLKTNEQVIGIDWNHNVSDLKGKFNALQKNYQQLFQSIDKFLIDYREALDYNKNNSNNKNGNLSLIKGNATINNNKNSDDKSNQDIKSQNLLTLNPLANALYMQLVGSKDFNKAFHRLEKLFSQVSKNDEYKIDNETYLRLVDLTCGILPFPNFQKLALLNKYKLDDRSVLINEMILQLIQIFENLQTNNSFVNNWFHSEATNIQKANVVANQLKSIRNLLEGMTKNRPIKSNKRNPGPASSSGPSFSNGKSSPGRANARPKSNHQDGFNGNDGDYNDVDDDDDGDEDLKAIFNFIKHKLPTISTLSADSKRLILKDFKRVKASANSPGGGGNSDFHVLRNYLEIVMDIPWDNYVTKFKSNKDIDLKLAKKQLDDDHYGLEHVKKRLIQYLVVLKLLGINAEKDQSDKSQPIKDNSKDSPNSSSKALTKSPTSSLSRKTISSIVIANKDETYLAKQQAKTTNQKSITEAKTNPSTTMITSNESIHVSKNNKSPIIMLAGPPGTGKTSLAKSIASALGRNFQRISLGGIKDESEIRGHRRTYVGAMPGLLIQALRKSRCMNPVILLDEIDKVIGGNNSGGVNKFNGDPSAALLEVLDPEQNNTFIDHYLGFPIDLSQVIFICTANDPWNMTRPLLDRLETIEIGAYDYNEKLIIGKKYLLPRQIKRNGFPVVDTKKMTTVVAGSSNQDEFIRINDATMKKVILDYTRGEAGVRNFERRLGTLCRFKAVEYCEWLNKDIKNYNPIIDENDLPIYLGVPYSSGDVTTEGTVGVGVVHGLSYNSDGSGSVLVFESIGFDRRISNKEHNGGNGATLNMTGRLGEVLMESGKIGLVFIKSMIYKNILKFDNNNNNKHLLLDKYNNLDIHMHVPMGSVSKDGPSAGVTMALSFLSVLLDKPVPSDIAMTGEITLRGIILPIGGVKEKLMGAHLNSNIKRMIVPRENRKDLIKEYSRSIEEAGEVLDHHLINDLIKDNEDKEFKLTQVEEYYQNKYGISLFYAKEFYDIIKIVWNEDEVLLKQDNSRLLEYHI
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix.  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: CYB_LAGHO
Sequence: MTNIRKTHPLMKILNDAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMFQETWNIGVLLLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAAVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGALLLILTLLALTLFTPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILVLIFIPMLQTSKQRSMMFRPFSQLLFWTLVADLLTLTWIGGQPVEHPYIIVGQLASILYFLLILVLMPTAGLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL24_FLAPJ
Sequence: MIKLKIKTGDIVRVIAGDHKGAEGKVVKVDREKNKAIVEGVNMVSKHTKPSAKSPQGGIVKKEAPIQISNVSLIDPKTKEATRVGIRVEGDKKVRFSKKSNQVL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: NDK_FRATW
Sequence: MTKQRTLSIIKPDAVEKNVIGEIYSRFEKAGLRIIAAKMKHLSKAEAERFYAVHKDRPFFSALVEFMISGPVMIQVLEGENAIAKNRELMGATNPKEAKAGTIRADFADSIDANAVHGSDAEDTAAQEIRYFFSDTEIFG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_CITK8
Sequence: MSHNDTIVAQATPPGRGGVGILRISGLKAREVAEAVLGKLPKPRYADYLPFKDADGTALDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTLPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNGVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPDFIARLPAKLPITVVRNKADITGETLGISEVNGHSLVRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALAEAAEHLQQGKSQLLGAWAGELLAEELRLAQQALSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_PSEPW
Sequence: MATERHYSPLDRLLLQADTAMRTLLPFSGQPSRPSPAIVQPDVELDESQTRHIAGLMRINHTGEVCAQALYQGQALTAKLPQVRKAMEHAAEEEIDHLAWCEQRIRQLGSHPSVLNPLFYGMSFGIGALAGMVSDKVSLGFVAATEHQVCKHLDEHLEQIPHEDEKSRAILEQMRVDEEQHADSALEAGGYRFPAPVRFGMSMLAKVMTKSTYRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YBAP_ECOLI
Sequence: MDLLYRVKTLWAALRGNHYTWPAIDITLPGNRHFHLIGSIHMGSHDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEEQLQNLQHISQEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEGAENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQSLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR
What are the official names of this protein?
Uncharacterized protein YbaP.
Protein: FABH_XANC8
Sequence: MSKRIYSRIAGTGSYLPEKVLTNDDMSKIVDTSDEWIRSRTGIRERHIVADDQTTSDLAYFASLKAMEAAGVTADEIDLIVVGTTTPDLIFPSTACLLQARLGNVGCGAFDVNAACSGFVYALSVADKFVRSGDAKTVLVVGAETLTRIVDWTDRTTCVLFGDGAGAVVLKADEDTGILSTHLHADGSKKELLWDPVGVSVGFGEGKNGGGALLMKGNDVFKYAVKALDSVVDETLAANGLDTHDLDWLIPHQANLRIIEATAKRLDLPMEQVVVTVDRHGNTSSASVLLALDEAVRSGRVQRGQLLLLEAFGGGFTWGSALLRY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities (PubMed:27595587).  Can use a wide range of acyl-CoAs as the primer substrate in vitro, with a slight preference for short, medium-straight chain acyl-CoAs (PubMed:27595587).  Can also use branched-chain acyl-CoAs and acetyl-CoA (PubMed:27595587).
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III, Branched-chain beta-ketoacyl-[acyl-carrier-protein] synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_EULMA
Sequence: MAYPVQLGFQDAASPIMEELLYFHDHTLMIMFLISSLVLYIISLMLTTELIHTSTMDAQEVETVWTILPAVILILIALPSLRILYMMDEISTPSLTLKTMGHQWYWSYEYTDYENLCFDSYMAPPSDLKPGELRLLEVDNRVVLPTELPIRMLISSEDVLHSWTIPSLGVKTDAIPGRLNQATLMASRPGVYYGQCSEICGANHSFMPIVLELVPLKHFEEWLLSML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYC_WOLPM
Sequence: MVRLYNTLTKKKELFTPIDKDHVKMYVCGPTVYDTAHIGNARSVVVYDVLFQLLKFCYGKVTYVRNITDIDDKIINAASEKNSNIESISTYYTKAFHEDMRSINCAEPTHEPKATKNVDYIIKLIEHLLQSGHAYESDKHVYFNIESYHEYGALSGKKTDELVPGSRVEVNENKKHPGDFVLWKPANDIDYKLSSYWNSPWGEGRPGWHIECSAMSYAYLGKDFDIHGGGIDLQFPHHENEIAQSKSAFAGSMFAKYWIHNGFLTVNEEKMSKSLFNIVKVRDLLDSGIKGEVIRYALLKTHYRKPLDWTENVISDAQETLNKFYRLSRGLDTINIDESNAEISKDFIDALKNDLNIPEALAILHEMAAKINKMSNESEKLKLTESFVKSARFIGLLESSYEKWFAVDVNHQEIERLIDLRKIAKKNKNYDTADKIRDQLKQMGITISDNEDGTTTW
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_ECOHS
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIVEGHELSSVFFYREGVYNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSNLQPGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_TRIEI
Sequence: MADQLIRAMAAEGGIRAVGVITTRLTEEARQRHKLSWVASVVLGRTMAAGLLLASSMKTPESRVNIRVQGNGPLGEVLVDAGLDGTVRGYVNNPTIELLPNKIGKHDIGKAVGNQGYLYIVRDIGYGYPYSGTVELVSGEIGDDITHYLAKSEQTPSALVLGVFVDKEGVQTAGGILLQVMPKVAIDEELVQVLESRIASLSGFTSLLHSGKTLPEIFQELLGDMGLNILPEAQIVRFKCDCSMEKVLRALRMFGVDELQNMIEEDKGAEVTCEFCSQLYQASPKELTQIIQDLQQPSTEVPLGQLRRSSH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_SYNS3
Sequence: MSKQAVLLDEAARQSLYSSCPAWTIASDGLVREWRFHSFVEAFGFMTQVALLAERANHHPEWSNVYNRVTIRLTTHDLGGLSSRDAELAQAIDSLSPTT
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: TYSY_PAEAT
Sequence: MSIPTPYEDLLRDVMANGTHKSDRTGTGTRSVFGRQLRFDLAESFPLITTKRVHFKSVAVELLWFLRGDSNVKWMQDQGVSIWDEWADADGELGPVYGVQWRSWPTPDGGHIDQISELMTNLAANPDSRRHIVSAWNVSELKDMALPPCHAFFQFYVADGKLSCQLYQRSADTFLGVPFNIASYALLTRMVAQQLGLEPGEFVWTGGDVHVYDNHVDQVAEQLSREPYEYPQLKILRKPDSIFDYTLDDFEVVDYRHHPTIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_THEP3
Sequence: MAISRSEVEHVAKLARLKFSQEEIEEFTVQLSKIIDYVNKLNELDTENVEPTAHIVPIHNVFREDEVKPSMDRDKILMNAPYKENGCFKVPKIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: THIG_ECO81
Sequence: MLHIADKTFASHLFTGTGKFASSQLMVEAIRACGSQLVTLAMKRVDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAETLVQQGFIVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAKAFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHMD_BURA4
Sequence: MAMPTIKHVRAFTVRGGGADYHDQDDGHWIDDHIATPMSRYPEYRESRRSFGINVLGTLVVEIEASDGSVGFAVTTGGEIGAFIVERHLARFLEGRCVTDIETMWDQMYYATLYYGRKGVVLNTISGVDLALWDLLGKVRGEPVYQLLGGPVRDELVFYATGARPDLAKQMGFIGGKLPLQHGPAENEEGLRKNLEKLADMRNRVGDDFWLMFDCWMSLDVRYATRLANAAHEYGLKWIEECLPPDDYWGYADLRRNVPRGMMVSTGEHEATRWGFRMLLEMGCCDLIQPDVGWCGGITELIKISALADAHNVMVVPHGSSVYSYHFVVTRHNSPFAEFLMMAPKADEVVPMFTPLLLDEPVPVNGRMKVPDRPGFGVRLNPECALVRPYTH
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.