PharMolix/UniProtQA huggingface dataset:
Protein: ZP2_RABIT
Sequence: PGTVTCNENEIIVEFPSYVGTKTLHASVVDPLGVEMLNCTYILDPEKLTLRVPYKACTRAVHGGYQMSIRVMNNSAALRHTDVEYQFFCPVEQTLEFSKSAACTKDFMSLSFPHIPTGLGDSTMVNESQMGWMVQAGHGPGAQTLSLEEAKGQGFGVLIDDNKMTLSVLLNATGVTHYVEGTSHLHTMFLKLSLVSPGQKMPFPSRAICLSGPVTCNATHMTLTIPEFPGKLESVSIENRNITVSQLHDQGIDVEAINGLRLHFSKTVLKTKFSEKCLHDQLYISSLKLTFNLELDTVSTVINPECPCDSPASIVSGELCTQDGFMDFEVYTHQTKPALNLDTLRVGSSSCQPVFKAQSQGLVRFRIPLNGCGTRHKFEDEKVIYENEVHALWENLPPSKISRDSEFRMTVQCYYTRDDMLLNANIKSLPPPVASVKPGPLALSLQTYPDESYQQPYRVNEYPIVKYLRQPIYMEVRVLNRNDPNIKLALDDCWATSSMDPASLPKWSIVMDGCEYSLDNYQTNFHPVGSSVTHPEHYQRFDVKTFAFVSEAQARSSLVYFHCSALICNQHYPDSPLCSVTCPGSSRHRRATGNTEEERVTASLPGPILLLPNGSSFRGVGDSKEHGMAGDVTSKTMAAVAAVAGVVATLGFISYLCKKRTMMLSH
What is the function of this protein?
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy.  The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4.  ZP2 may act as a secondary sperm receptor.
What are the official names of this protein?
Zona pellucida sperm-binding protein 2, 75 kDa zona pellucida protein, Zona pellucida glycoprotein 2, Zp-2, Zona pellucida protein A.
What is the protein family that this protein belongs to?
Belongs to the ZP domain family. ZPA subfamily.
What are the subcellular locations of this protein?
[Processed zona pellucida sperm-binding protein 2]: Zona pellucida. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: TYSY_SACD2
Sequence: MKQYLDLMRHVRDTGTKKEDRTGTGTVSVFGYQMRFDLSEGFPLVTTKKCHLKSIIHELLWFLKGETNTQYLTDNGVRIWNEWATEEGDLGPVYGAQWRSWPTPDGGSLDQFALLVEQIKNKPDSRRHIISAWNPALLPDEGVSPQDNVRNGKMALPPCHTLFQFYVADNKLSCQLYQRSADIFLGVPFNIASYALLTMMVAQVTGLELGDFVHTFGDAHLYLNHLEQVETQLAREPLPLPTMKINPEVKDIFSFKFEDFELVDYQAHPHISAPISI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG35_ICHVA
Sequence: MTAPMSIEPETGSSPGLTELISKWGRLSDSFLERRLTNISSARQEITAIKTENEARAKALRQSLEEDRAFWTNKITALGYKVAKRRMAMVTTEPGESTAPHLEVVHSDKGLLGLFEISAGDQLLCPSAITPFIRDRGGPGTCPLCLRTFDQKLEGHIYTELISSGHGVSRGSDGAWRAHFTGDTPPVLFPRKTLGKERAATLSAAIKQFKCLQVDHCTLEGIIESLAIKAHKILDLCE
What are the official names of this protein?
Uncharacterized protein ORF35.
Protein: UBIA_HAEDU
Sequence: MQLMRFDKPIGTLLLLHPTLWALFAAAGGIPSSSILIIFILGVIVMRAAGCVINDYADRHIDGKVKRTSQRPLATGRVTTVEAKVLFFVLLIIAFLLDLSLNQYAFLLSFVAVALAVIYPFMKRFTHLPQVVLGMAFGWAIPMAYGAVIEDLPLTCWLLFLANILWTVAYDTQYAMVDRDDDLRIGVKSTAILFAQYDNKIIALLQFLSLILFILFGWLSEYHIGYFIVLALTSTLFIYQCWLTKQRVREQCFKAFLNNNYFGFGIFIAILVGIYGF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEP2_FUSSL
Sequence: MVNLHSLPQGSRPNAAIRNNGPDSLALERLKLRELAEGWPSYRDSCEWENFESIFHPGAYVYTTWSGRVAYQDFIAASKAGMDKGAFIMHRCHGSSTDINVDGTRAVTKLKATITQRFEVGGSEFDVEADCRFCFYFEKINGSWGARLVKHWYEKDKMIPVNPAKFPQVDEDKLKAYPPGYKYLAYWQETAMGIKVLLDMPGHRRHVGTVNLEKHDELYWLAKRWLEGEQIEV
What is the function of this protein?
Contributes to the ability of the fungus to cause disease on pea plants.
What are the official names of this protein?
Pea pathogenicity protein 2.
What is the protein family that this protein belongs to?
Belongs to the PEP2 family.
Protein: WDR64_HUMAN
Sequence: MDIRKEKRLNMALQMSNFKKALNRFEKLVEQTAAQKRDERAGLFIHKEDAIGYDKFYASVQKLFGPDVKNQDVKRFYRKLCNNTDASADWCEIFGYFSSEEDPIASQLDEENLVFFVSRKRRILISGSRRRDVIKSIVKIPHLDLLITATQKGLITVFNNQDTSWITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCLLCVCVVPLPDHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNFKSVKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFCYCVKANVIVTGGDDKVIRLWHPNISTKPVGKLVGHMFSIAEIVTNEKDQHVVSLSSAKVFRVWDIQTLSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVMDMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVYQILEPHGFNTEVTSAAVDESGFLFATGAYNGTVRIWDFGSGQEMKVLPEGKDWKEDEHCLRRLIFLKAQEKHQQLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKHAVHLRMSTRDRNMAIPFPDVELIVERNFSQPTDNPTMDLLRVNCIDLLQVEGYNLIAAGTLNGVIILWNFVTSTVKKVYRPEDCFTVNPDLHPKHFKINDILFLFRTPECARRSSQDSICSSSQCESSKGPQSSKGSKQSIHDSEVKGEQTDVMVGKQQPMDKKHPGIANLPEAQPPILVTAHEDGHLRLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAGNVEGHVILCNISSFLDPPHDEKKFKQLLSWRAHSLEIIQVIYVEEKQVVLTASIDGSVRLWHALNGHYCGYFGQRRLFELSQTRDFILPCDVTEYPIEIKEESKFTEKQKYEYPLIFDREKWRKMSSVSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGSLPIYSISSPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQREKAPRRRSLKKNLVPQINLASSFFPAIPK
What are the official names of this protein?
WD repeat-containing protein 64.
Protein: PUR9_XYLF2
Sequence: MASDFLPVHRALLSVSDKTGLVELARVLLAYNIELLSTGGTATIIREAGLPVQDVADLTDFPEMMDGRVKTLHPVVHGGLLGRAGIDDAVMAKHGIAPIDLLIVNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRSAAKNFARVAVATSPDQYPDLLAELQAHHGQLSAEKRFALAVAAFNHVAQYDAAISNYLSSVSDMHTTLPLRHEFPTQLNNTFVKMTDLRYGENPHQSGAFYRDVHPQPGTLATFKQLQGKRLSYNNLVDADAAWECVRQFEAPACVIVKHANPCGVAVGTACSDAYEAAYATDPTSAFGGIIAFNRTLDAVTMQSILDRQFVEVLIAPYYDADALAYATKKANVRVLRIPSTGAMNRYDFKRIGSGLLVQSADSLNIHSGALKVVTQLAPTYAQQRDLLFAWHVAKYVKSNAIVYAKDNRTIGIGAGQMSRVYSARIAGIKAADAHLAVTGSVMASDAFFPFRDGIDAAAATGIKAVIQPGGSMRDNEVIAAADEHGIAMVFTGIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: GCSP1_PSEAE
Sequence: MTDNLNLGAIDLGTDDEFIARHIGPRAADTQAMLQRLGYDSLDTLIGNVIPDSIKGSSVLDLPAGMGEAEALASLKAIAARNRALRSFIGQGYYNCHTPAPILRNLLENPAWYTAYTPYQPEISQGRLEALLNFQTLVSDLSGLPIANASMLDEATAAAEAMTFCKRLSKNRTSQAFFASRHCHPQTLDVLRTRAEPLGIEVVVGDESTIEDFSAYFGALLQYPTCDGEIVDYRELVSRFHAVDALVAVAADLLALTLLTPPGEFGADVAIGSAQRFGVPLGFGGPHAAYFATRDAFKRDMPGRLVGVSIDRHGKPAYRLAMQTREQHIRREKATSNICTAQVLLANIASMFAVYHGPQGLLRIARRTHRLTAILAAGLERLGVAVEQKHFFDTLSLATGARTAAIHAKARAAGINLREIDAGRLGLSLDETVRQTDVETLWGLLAEEGQALPDFAALAASSGDRLPVELLRQSAILSHPIFNRHHSETELMRYLRKLADKDLALDRTMIPLGSCTMKLNAASEMIPVTWAEFGNLHPFAPAEQSEGYRQLTDELEAMLCSATGYDAVSLQPNAGSQGEYAGLLAIRAYHQSRGDSQRDICLIPSSAHGTNPATASMVGMRVVVVACDARGNVDVEDLRNKASEHKERLAALMITYPSTHGVFEEAIREICAIVHDCGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVRAHLAPFLPGHARGERKEGAVSAAPYGSASILPITWMYIRMMGGEGLKRASEMAILNANYIAHRLEEHYPVLYAGGNGLVAHECILDLRPLKDSSGISVDDVAKRLMDFGFHAPTMSFPVAGTLMIEPTESESKAELDRFCDAMIRIREEIRAVERGELDKEDNPLKNAPHTAAELLGEWNHAYSREQAAYPLASLVEAKYWPPVGRVDNVYGDRNLTCSCPPIEAYSEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating) 1, Glycine cleavage system P-protein 1, Glycine decarboxylase 1, Glycine dehydrogenase (aminomethyl-transferring) 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: HIS3_CORGB
Sequence: MSDNPQEYELDWDVEKRLKLNDAGLVPAIVQADGTNEVLMMAWMDTHALAYTLATRRGTYFSRSRNEYWIKGLTSGNVQEVTGVALDCDGDTVLLTVKQTGGACHTGAHTCFDNDVLL
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_MYCMM
Sequence: MAEPVDLDVAGPVGRPVLVVDFGAQYAQLIARRVREARVFSEVIPHTTSIEEIKARDPLALVLSGGPASVYAPGAPQLDPALFDLGLPVFGICYGFQVMAQALGGTVAHTGTSEYGRTELKVLGGDLHSDLPDIQPVWMSHGDAVTAAPDGFEVVASSAGAAVAAFENRERRLAGVQYHPEVMHTPHGQQILGRFLHDFAGIGARWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRAIGDRLTCVFVDHGLLRAGERAQVERDFVAATKANLVTVDVADTFLAALSGVTDPEGKRKIIGRQFIRAFEGAVRDVLDGRDIEFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDLKFALVEPLRLLFKDEVRAVGRELGLPEEIVARQPFPGPGLGIRIVGEVTGQRLDTLRRADSIAREELTAAGLDNQIWQCPVVLLADVRSVGVQGDNRTYGHPIVLRPVSSEDAMTADWTRVPFEVLERISTRITNEVPEVNRVVLDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DTD_STAA8
Sequence: MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTLYADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CR1CB_BACTG
Sequence: MENNIQNQCVPYNCLSNPEEILLDGERISTGNSSIDISLSLVQLLVSNFVPGGGFLVGLLDFVWGIVGPSPWDAFLVQIEQLINERIAAYARSAAISNLEGLGNNFNIYVEAFKEWEADPDNPVTRTRVVDRFRILDGLLERDIPSFRIAGFEVPLLSVYAQAANLHLAILRDSSIFGARWGLTTINVNENYNRLIRHIDEYANHCADTYNRGLNNLPKSTYQDWITYNRLRRDLTLTVLDIAAFFPSYDNRRYPIQSVGQLTREIYTDPLITFNPQLQSVAQLPTFNVMESNAIRTPHLFDVLNNLTIFTDWFSVGRNFYWGGHRVISNRIGGGNITSPIYGREANQEPPRSFTFNGPVFRTLSNPTFRPLQQPWPAPPFNLRGVEGVEFSTPLNSFTYRGRGTVDSLTELPPEDNSVPPREGYSHRLCHATFVQRSGTPFLTTGPVFSWTHRSATDRNIIYPDVINQIPLVKAFNLTSGTSVVRGPGFTGGDIIRTNVNGSVLSMSLNFSNTTLQRYRVRVRYAASQTMVMSVTVGGSTTGNQGFPSTMSANGALTSQSFRFAEFPVGISASGSQGASISISNNVGRQMFHLDRIEFLPVTSTFEEEYDLERAQEAVNALFTSTNQLGLKTDVTDYHIDQVSNLVECLSDEFCLDEKRELSEKVKHAKRLSDERNLLQDRNFRSINGQLDRGWRGSTDITIQGGDDVFKENYVTLPGTFDECYPTYLYQKIDESKLKSYTRYELRGYIEDSQDLEIYLIRYNAKHEIVNVPGTGSLWPLSIENSIGPCGEPNRCAPHLEWNPNLDCSCRDGEKCAHHSHHFSLDIDVGCTDLNEDLGVWVIFKIKTQDGHARLGNLEFLEEKPLLGEALARVKRAEKKWRDKREKLEWETNIVYKEAKESVDALFVNSQYDRLQADTNIAMIHAADKRVHRIREAYLPELSVIPGVNAGIFEELEGRIFTAYSLYDARNVIKNGDFNNGLLCWNLKGHVDVEEQNNHRSVLVVPEWEAEVSQEVRVCPGRGYILRVTAYKEGYGEGCVTIHEIEDNTDELKFSNCVEEEVYPNNTVTCNDYTATQEEYGGAYTSRNHGYGKSYESNSSVQADYASVYEEKADTDGRRDNHCESNRGYGDYTPLPAGYVTKELEYFPETDKVWVEIGETEGTFIVDSVELLLMEE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.  Toxic to Spodoptera exigua and Trichoplusia ni.
What are the official names of this protein?
Pesticidal crystal protein Cry1Cb, 133 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIC(b).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: PYRR_PASMU
Sequence: MEKIIIDENQFLRTISRISHEIIEKHQRLDNIVIVGIKRRGAEIAELIKKKIADLANVELPSIDLDITFYRDDLEYAEPDSKSPTYSGASSFISIHNKEVILVDDVLYTGRTIRAALDALVDFGRAAKIELVIFVDRGHRELPIRADYVGKNVPTSRSEEVQVRTLKFDNCYEVALLSPTK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: WTPC_PYRFU
Sequence: MLEVQGISKKWKDFHLKDISFSVMDGEYFIVLGPSGAGKTVLLEIIAGIIPPDGGKVLLDGKDITLLPPEKRGIAYVPQNYALFPNMSVFDNIAFGLKVRRVPRSEIEKRVLEISEVLGIRHLLHRKPRTLSGGEQQRVAVARALVIEPEIILLDEPFANLDVQIRSRLINEMKRWRRELGFTAIHVTHSFEEALALGDRVGIMLNGKLVQVGEIREVFSRPNSEEVAKFLGFENIIEGIADGRVLHVGKLRIELPLEAKGRVRIGIRPEDILISTERIKTSARNVFKAKVEAIEDVGPLVKLTLNVCDITLRAFITRSSLVELGIEEGKEVYASFKASAIHVF
What is the function of this protein?
Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdate/tungstate import ATP-binding protein WtpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TIP42_MAIZE
Sequence: MAKLVNKLVDSFDHDEAPAPDVGCVRAVLAELVLTFLFVFTGVSASMAAGAGGKPGEAMPMATLAAVAIAHALAAGVLVTAGFHVSGGHLNPAVTVGILVRGHITKLRALLYVAAQLLASSLACILLRYLSGGMVTPVHALGAGIRPMQGLVMEVILTFSLLFVTYAMILDPRSQVRTIGPLLTGLIVGANSLAGGNFTGASMNPARSFGPAMATGVWTNHWVYWIGPLLGGSLAGFVYESLFMVNKTHEPLLNGDI
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin TIP4-2, Tonoplast intrinsic protein 4-2, ZmTIP4-2, ZmTIP4;2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC 1.A.8.10) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: SYFA_THETH
Sequence: MLEEALAAIQNARDLEELKALKARYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIKAALEAALEAREKALEEAALKEALERERVDVSLPGASLFSGGLHPITLMERELVEIFRALGYQAVEGPEVESEFFNFDALNIPEHHPARDMWDTFWLTGEGFRLEGPLGEEVEGRLLLRTHTSPMQVRYMVAHTPPFRIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALFGPDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLPPAYRGVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKFLEQFKGVL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_RHIFI
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSAWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATTFNSVTHICRDVNYGWLIRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNVGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSALVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPVLHTSKQRSMMFRPLSQCLFWLLVAILFTLTWIGGQPVERPFIIIGQTASVLYFLIILILMPVTSLMENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SNMP1_DROSE
Sequence: MQVPRVKLLMGSGAMFVFAIIYGWVIFPKILKFMISKQVTLKPGSDVRELWSNTPFPLHFYIYVFNVTNPDEVSEGAKPRLQEVGPFVFDEWKDKYDLEDDVVEDTVSFTMRNTFIFNPKESLPLTGEEEIILPHPIMLPGGISVQREKAAMMELVSKGLSIVFPNAKAFLKAKFMDLFFRGINVDCSSEEFSAKALCTVFYTGEVKQAKQVNQTHFLFSFMGQANHSDSGRFTVCRGVKNNKKLGKVVKFADEPEQDIWPDGECNNFVGTDSTVFAPGLKKEDGLWAFTPDLCRSLGAYYQHKSSYHGMPSMRYTLDLGDIRADEKLHCFCEDPEDLDTCPPKGTMNLAACVGGPLMASMPHFYLGDPKLVADVDGLNPNEKDHAVYIDFELMSGTPFQAAKRLQFNLDMEPVEGIEPMKNLPKLILPMFWVEEGVQLNKTYTNLVKYTLFLGLKINSVLRWSLITFSLVGLMFSAYLFYHKSDSLDINSILKDNNKVDDVASTKEPMPPANPMQSSTVHPVQLPNTLIPGTNPATNPATHLKMEHRERY
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y119_NPVOP
Sequence: MYFLILILVLLLIMVAAATAYVNLIDVHHEDVRPPLQMFDTGNVPLIEPPGEIVTEGNAHECHKALTPCDTHADCNACREGLANCQLFDEETMVQMRDADGNEQSATIRAGESYCFALDRERARSCNPGTGVWLLAQTETGFALLCSCLRPGLVTQLNMYEDCNVPVGCAPHGHVAGVGADARCVFDEGYVIDYDAATETPFCRPRTVRDVLFDEAFFPRAPCADGQVRLDHPGLNDYYRRYFRIEDICVVDPCSVDPISGRRTSGRLFYHAADGVEVSGCNCPAADGLLPVFNRHVADSGMVPRGDRTVANACLHPFNVHMLALRHVDYKFFWARPDHDEVADADVVFQADERQLSHERYRAMLYPLLRFHPEETSLVWGDSRVLKISVSYDTVLKNALLPPSLFQLFKRKERATSEPACFFPGEGRCIVHNSETCIRRHANGQVWTAETFTGSWCVLSRDGAAIKVWSRAERYPRGAAPAALRLRGFFFNNDRERNTVRVVNTGDMASGAQTDALTQVLDTFSNYSV
What are the official names of this protein?
Uncharacterized 59.0 kDa protein.
Protein: GRPE_RHIL3
Sequence: MTDDTTKNGPDATAADAAADATAYVENETAQQEPAQPDPIELLKAENGELRDRYLRLAAEMDNLRRRTEREVKDAKSYSVAGFARDMLAVSDNLRRALDAISPETKATADAGLSTLIEGVEMTERAMLSALERHGVRKLEPVGQKFDPNFHQAMFEVPNPDVPNNTVVQVVQAGFTIGERVLRPAMVGVAKGGPKPAEAETNSVFDEKDA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JAM1_BOVIN
Sequence: MGTKAKVGSTELLLFTSMILCSLALGRGAVQTYEPVVRVPENNPAKLSCSYSGFSSPRVEWKFTHGDIRGLVCYNNKITASYENRVTFSDTGITFHSVTRKDTGMYTCMVSDEGGNTYGEVTVQLIVLVPPSKPTINVPSSVTIGTRAVLTCSERDGSPPSEYKWFKDGVEMPLEPKSNRAFSNSSYTLNQKTGELIFDPVSASDTGDFTCQAQNGYASPVKSDTVHMDAVELNVGGIVAAVFVTLILLGALIFGIWFAYSRGYFDRAKKGTSNKKVIYSQPNARSDGEFRQTSSFLV
What is the function of this protein?
Seems to play a role in epithelial tight junction formation.  Appears early in primordial forms of cell junctions and recruits PARD3.  The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly.  Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier.  Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration.  Involved in platelet activation.
What are the official names of this protein?
Junctional adhesion molecule A, JAM-A, Junctional adhesion molecule 1, JAM-1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein. Note=Localized at tight junctions of both epithelial and endothelial cells.
Protein: NQRB_PSEAE
Sequence: MGLRNLLDKVEHHFEKGGRYEKWYPLYEAVDTFLYRPGSVTRTTAHVRDGIDLKRMMIIVWLCTFPAMFFGMYNVGHQANLIFAQSPDLLSAQDGWRFALIGALAGFDPNSLWDCLVQGAAYFLPVYLTTFIVGGFWEVLFASIRRHEVNEGFFVTSVLFALTLPPSVPLWQVALGISFGVVLGKEVFGGTGKNFLNPALVGRAFLFFAYPAQMSGDAVWTSVDGFAGATSLSLAAAGGVDNILGHGLTWMDAFLGHMQGSMGETSTLAIFIGGAVLLLTRIASWRIVAGVMLGMVAMSYLFNAIGSASNPMFAMPWYWHLVTGGFAFGMIFMATDPVSASMTDTGKWLFGALIGVMVMLIRVVNPAFPEGMMLAILFANLFAPLIDHFVVQANIKRRLARNG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SRRA_STAAN
Sequence: MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMDGIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRTQSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDREQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPAK
What is the function of this protein?
Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation.  Also plays an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate (By similarity).  Functions as a transcription regulator by direct binding to promoter regions of target genes (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein SrrA, Staphylococcal respiratory response protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM9B_MOUSE
Sequence: MASLWCGNLLRLGSGLSMSCLALSVLLLAQLTGAAKNFEDVRCKCICPPYKENPGHIYNKNISQKDCDCLHVVEPMPVRGPDVEAYCLRCECKYEERSSVTIKVTIIIYLSILGLLLLYMVYLTLVEPILKRRLFGHSQLLQSDDDVGDHQPFANAHDVLARSRSRANVLNKVEYAQQRWKLQVQEQRKSVFDRHVVLS
What is the function of this protein?
Enhances production of pro-inflammatory cytokines induced by TNF, IL1B, and TLR ligands.  Has a role in TNF activation of both the NF-kappaB and MAPK pathways.
What are the official names of this protein?
Transmembrane protein 9B.
What is the protein family that this protein belongs to?
Belongs to the TMEM9 family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass membrane protein. Early endosome membrane; Single-pass membrane protein.
Protein: RISB_ANOFW
Sequence: MNVYEGNLVGTGLKIGIVVARFNEFITSKLLSGALDGLKRHGVEEQHIDVAWVPGAFEIPLVAKKMAESKKYDAVITLGAVIRGATSHYDYVCNEVAKGTSHAALSSGVPVIFGVLTTDTIEQAIERAGTKAGNKGWEAALSAIEMANVMRTFS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.