PharMolix/UniProtQA huggingface dataset:
Protein: SYS_BURTA
Sequence: MLDIQLLRKDLDGVAKRLADRGYTLDVAAFSALEAERRAIQTRTEELQARRNSLSKQIGAMKGRGEDTSAVMAEVGGIGDEMKASAVKLDEIQARLSELMLEMPNVPHESVPVGRDETENVEVRRWGAPRQFDFDVKDHVDVGTPLGLDFETGAKLSGARFTVLRGPIARLHRALAQFMLDTHTQQHGYSETYTPYIVNPDVLYGTGQLPKFAEDMFRVEKGGAENTVTQYLISTSEISLTNTVRDSIVDASALPIKLTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVAPEASYAALDEMVGHAEAILQTLELPYRVVALCTGDMGFSAAKTFDLEVWLPAQNTYREISSCSNTESFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVAVLENYQNADGSVTVPVALRPYMGGVERIAAPSSAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_CAMJR
Sequence: MEVITSIKEAKQTVKNWKSHNLSIGYVPTMGFLHDGHLSLVKNAKTQDKVIVSIFVNPMQFGPNEDFSSYPRDLERDIKMCQDNGVDMVFIPDAAQMYLKNFSTYVDMNTITDKLCGAKRLGHFRGVCTVLAKFFNILNPDIVYMGQKDAQQCVVVRHMVDDLNFDLKIQICPIIREEDGLAKSSRNVYLSEEERKASLAISQSIFLAEKLVQEGEKDTSKIIQAMKDILEKEKLIKIDYIELVDFNTMENIKNIADNVLGAVAAFVGKTRLIDNFLVQGLK
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_BACC1
Sequence: MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKQLEENNQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARRC_BOVIN
Sequence: MSRVFKKTCSNGKLSIYLGKRDFVDHVDMVEPIDGVVLVDPEYLKGRKMFVMLTCAFRYGHDDLDVIGLTFRKDLYVQVQQVVPAESSSPRGSLTVLQERLLHKLGDNAYPFTLQMVVNLPCSVTLQPGPDDTGKACGVDFEVKSFCAENLEEKVSKRDSVRLVIRKIQFAPLEPGPGPWARLCRRFLLSAQPLLLQAWMDKEVNYHGQPISVNVSINNSTNKVIKKIKISVDQITDVVLYSLDKYTKTVFVQEFTETIAANSTFSKSFAVTPLLADNCHKQGLALDGKLKQGDTNLASSTILRPGVDKELLGILVSYKVRVNLMVSCEGILGDLTASEVGVELPLILMHPKPSNEAASSEDIVIEEFAQQEPSGESQEALAAEGNEGS
What is the function of this protein?
May play a role in an as yet undefined retina-specific signal transduction.  Could bind to photoactivated-phosphorylated red/green opsins.
What are the official names of this protein?
Arrestin-C, Cone arrestin, cArr, Retinal cone arrestin-3, X-arrestin.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Protein: LMBD1_XENTR
Sequence: MATGSTELLIGWCIFGVLLLAILAFCWVYVRKYQSHQESEVISTITAISSLAIALITSALLPVDIFLVSFMKNHNGTFKDWAESNTTRLQIENTVLIGYYTLYSIILFCVFLWIPFVYFYYEEKDDTDGSQCSQIANAFKYTSGFILVCSCLLLIGAFAPLDIHTNKNSTDLDKIKLLFLELGSSNGLAALSFSISSLTLIGMLAAITYTAYGMSALPLNLIKGTRNAHYERLENSEDIEEVEQQVERIMSKCKDGRPLSSKDRQALYKLKEKLRTLKRRDRHLEYHENNCWTKCCIVIRPFKIIWGILFILVALLFIVSLFLSNLDKALHSAGIDSGFIIFGTNLTNPLNMLLPVLQTVFPLDYIFITIITMYFIFTSMAGIRNMGIWFFWIRLYKIRRRRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQKYLWENNSTQETAIGNSSASVLKDCDASAPEDQCTVTRTYLFLHKFWFFSSIYYFGNWAFIVVFVIGLIVSCCKGKKSVIEGEVEDDDSDLSDDEEHPYA
What is the function of this protein?
Lysosomal membrane chaperone required to export cobalamin (vitamin B12) from the lysosome to the cytosol, allowing its conversion to cofactors.  Targets ABCD4 transporter from the endoplasmic reticulum to the lysosome.  Then forms a complex with lysosomal ABCD4 and cytoplasmic MMACHC to transport cobalamin across the lysosomal membrane (By similarity).  May play a role in mediating and regulating the internalization of the insulin receptor (By similarity).
What are the official names of this protein?
Lysosomal cobalamin transport escort protein LMBD1, LMBD1, LMBR1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: FLAV_BUCAI
Sequence: MKKIGIFFGSDTGNTEKIAKLIQKYIGDNVSCLYDISNTSQKDIEDFNFLIFGVPTWYYGEVQCDWDDFLPTLKKINFSNKIVALFGCGDQEDYSEYFCDAIGTIYDILKKNKANIIGKWSTEDYYFEQSKALLNKKYFYGLILDEDRQANKTEYRIKQWVKQIIPYFNTH
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.
What are the official names of this protein?
Flavodoxin.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: MNMG_STAA2
Sequence: MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOCS3_CANLF
Sequence: MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVCKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPAPPTEPSSEVSEQPPSQPLPGNPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGAIREFLDQYDAPL
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway.  Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including IL6ST/gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors.  Binding to JAK2 inhibits its kinase activity and regulates IL6 signaling.  Suppresses fetal liver erythropoiesis.  Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells (By similarity).  Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
What are the official names of this protein?
Suppressor of cytokine signaling 3, SOCS-3.
Protein: TENS1_MOUSE
Sequence: MGCTVSLVCCEALEPLPSCGPQPPGTPPGPARPERCEPGGAAPDPRRRLLLQPEDLEAPKTHHFKVKAFKKVKPCGICRQAITREGCVCKVCSFSCHRKCQAKVAAPCVPPSSHELVPITTETVPKNVVDVGEGDCRVGSSPKNLEEGGSMRVSPSIQPQPQSQPTSLSRNTSVSRAMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRPDITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYLHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQASICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDEAFKDDRFPDYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHREDGMEEVVGHTQGPLDGSLYAKVKKKDSLNGSSGPVTTARPALSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVSGATTAPAALSPQEKKELDRLLSGFGVDREKQGAMYRAQQLRSHPGGGPTVPSPGRHIVPAQVHVNGGALASERETDILDDELPIQDGQSGGSMGTLSSLDGVTNTSESGYPETLSPLTNGLDKPYSTEPVLNGGGYPYEAANRVIPVHSSHSAPIRPSYSAQEGLAGYQREGPHPAWSQQVTSAHCGCDPSGLFRSQSFPDVEPQLPQAPTRGGSSREAVQRGLNSWQQQQPHPPPRQQERSPLQSLARSKPSPQLSAETPVAALPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLLGSSRQSHPLTQSRSGYIPSGHSLGTPELVSSGRPYSPYDYQLHPAGSNQSFHPKSPASSTFLPSPHSSAGPQEPPASLPGLIAQPQLPPKETTSDPSRTPEEEPLNLEGLVAHRVAGVQARERQPAEPPGPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPHSVARSPPGLAKTPLSALGLKPHNPADILLHPTGVARRLIQPEEDEGEEVTKPPEEPRSYVESVARTAVAGPRAQDVEPKSFSAPAAHAYGHETPLRNGTPGGSFVSPSPLSTSSPILSADSTSVGSFPSVVSSDQGPRTPFQPMLDSSIRSGSLGQPSPAALSYQSSSPVPVGGSSYNSPDYSLQPFSSSPESQGQPQYSAASVHMVPGSPQARHRTVGTNTPPSPGFGRRAVNPTMAAPGSPSLSHRQVMGPSGPGFHGNVVSGHPASAATTPGSPSLGRHPVGSHQVPGLHSSVVTTPGSPSLGRHPGAHQGNLASSLHSNAVISPGSPSLGRHLGGSGSVVPGSPSLDRHAAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSSPVANGMASGSSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTITQQGKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSVIPLALPCKLVIPSRDPTDESKDSSGPANSTTDLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR
What is the function of this protein?
May act as a protein phosphatase and/or a lipid phosphatase (By similarity).  Involved in fibrillar adhesion formation (By similarity).  Essential for myofibroblast differentiation and myofibroblast-mediated extracellular matrix deposition (By similarity).  Enhances RHOA activation in the presence of DLC1 (PubMed:26427649).  Plays a role in cell polarization and migration (By similarity).  May be involved in cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity).
What are the official names of this protein?
Tensin-1.
What is the protein family that this protein belongs to?
Belongs to the PTEN phosphatase protein family.
Protein: CSN11_ASHGO
Sequence: MDQFEVLVAVERLFFAWEQISDKETLVERLEGRLADMNLSLSTSPHRSLFLPYLGTRKDHNVADPDTISSEYGLQLLVLENALAHNYSKAISLLESSTVGDVGYIEWCRCMMRLNILGKSYGNNSELDIGLRSYLRNGAQGSSLLLTDEVSDCRMLGFASLFLQEEYFIAVHHMVRSIHEHPSLVDYLLREEDGRDIFILKEEYKLMLTIAVLVAIPLENYQDFLLLEDLNPLLQGLPELHVCLNLLVSTSFGSFFARWLGPIQELANRSCFLAPVWHSVNSHMRSKILVFYIKISERVTVSYLARTLDIPYDTVMADVSSLIQKFDINIGIEGDLVYYKEDLPVGNLVSKVSQIQREIDSKLLVMKQKNDALRSFIENMLKEQSVEPLNRSQDMDAFELHEQSEDEEYEEEHLEEGENV
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes The CSN complex is involved in the regulation of the mating pheromone response.  PCI8 may also be involved in transcriptional and translational control (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 11.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DDL_CLOAB
Sequence: MKKKVAILFGGQSTEHEVSRVSAASVLRNIDTSKYDLFPIGITKKGEWFEYTGSADKIENGEWEKDEFYKSPNGQAILFNKEVDVVFPVMHGLYGEDGTIQGLCKLVGVPCVGPSVLSSSVCMDKVYTKYVLEHFNIKQADYVVVHAHEYKTSKEEIIKEIENKLGYAVFIKPSNSGSSVGITKAHNRKELEAGLEEAMKYDRKILVEEALNAREIEVAVLGNEEPKAAIPGEIVPAKEFYDYEAKYENAASKLLIPANLSNENLEKIKNIAIEVYKALDCSGMSRVDFLVDKDTTEMYLNEVNTIPGFTSISMYPKLWAAAGKDYSKLIDELIELAASRNNA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_ALKCK
Sequence: MQVMQPARLPHHYREMSSAEKEARIREAKAFFGNDLLIPGHHYQREDVIQFADFTGDSLQLAQLCGQTSSANIVFCGVHFMAETADMLTSREQHVILPDLAAGCSMADMASIAQTERAWEALTERFGDTILPLTYVNSTAEIKAFCGRHGGACVTSSNAKNMVQWAFAQKPRVMFLPDQHLGRNTAFALGIPLEKMAVWNPHTHELELLPGANIEEIIVILWKGHCSVHEKFTVEQIKNVRDRSPHTQVIVHPECTHEVVQAADKAGSTHYIIETLKQAEPGTSWAIGTEMNLVNRLAKQHPDKQVFSLHSTMCLCLTMNRIDLDHLAWSLDLLREGKRQFEITVAEDVAAEARTALARMLATV
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_PARPJ
Sequence: MEFLDLGPFSRASGTIRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALEKLGVRLKRDGDTCVVTGTRGAFTARTADLFLGNAGTAVRPLTAALAVNGGDYRIHGVPRMHERPIGDLVDGLRQLGARIDYEENEGYPPLRIRPGQINADAPITVRGDVSSQFLTSLLMTLPLLRTESGVSTVQVDGELISKPYIEITIKLMERFGIKVERHGWHQFVVPAGQRYQSPGTIMVEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFADALIKMGANLQMGDDWIEVRGVGHDSGKLEPIDMDCNLIPDAAMTIAVAALFADGATTLRNIASWRVKETDRLAAMATELRKVGAKVQEGEDYLVIEPPEKLTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKTFPDYFERFTALAQP
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCA3_ARATH
Sequence: MGTMGKAFYSVGFWIRETGQALDRLGCRLQGKNHFREQLSRHRTLMNVFDKTPNVDKGAFVAPNASLSGDVHVGRGSSIWYGCVLRGDANSISVGAGTNIQDNALVHVAKTNLSGKVLPTVIGDNVTIGHSAVLHGCTVEDEAYIGTSATVLDGAHVEKHAMVASGALVRQNTRIPSGEVWGGNPAKFLRKVTEEERVFFSSSAVEYSNLAQAHATENAKNLDEAEFKKLLNKKNARDTEYDSVLDDLTLPENVPKAA
What is the function of this protein?
Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide.  Mediates complex I assembly in mitochondria and respiration (By similarity).
What are the official names of this protein?
Gamma carbonic anhydrase 3, mitochondrial, AtCA3, GAMMA CA3.
What is the protein family that this protein belongs to?
Belongs to the gamma-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein; Matrix side. Note=Probably integral to the membrane.
Protein: EFCB5_HUMAN
Sequence: MNESASQEELRPAQENRKEDKERKWNLTEVKELHETLQSVPDVPVKEDTNSVVEKAMDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKKNLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLDKLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQRLMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIIVKVANTRKQALQEQFDEWILDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKDLKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELFYDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEEQANLIYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVSETLTSFFKEGYVETEQEKMNALEQFSQNAFQVRQRLLLEAIFQKWDSDGSGFLDLKEVDELLYTYKEGMEKESMKKAKLHIQFPKPHPGHEVRLSSKQFQNYIELVVSELRGNEDQVLESVVEFLMNALERSHIESLRNSARRKWLHQIQCAAETSGVSLEPVYSETFKALMQDAEAHGNKKISAHISLLEENLLLPEKGNVLLRNVACTLDDAQFVLNRVLYRDMKGISFTVVDEGKPIHVPQVQYHGNIFFWNQSRNKHDYNGSFLALPLQDAYMRIFGVLAVDTLRDPHEINIFLPHEIRFYQGVANVFSTAYHYVHSREHILHIVITGIGWLYDVTSSITSITTYFVEPSPAQDSDYVLRNMMVTGQLGLTEIHKNPPTIHRKSCIFRDFLFKCTDSSEVVLASACGETHIVVPLRERTGEALGVLDFNIGQNRMLLCQEYKDLQKMMKVVQVACYEILGEFSGEIKKKYILEIENVREVQRAGILFFRIMLLELQESIQLLNSMEFVSLLLYDHTLVTEPNSPQDSKSMELEANVKLVRDILKAVILFFHPELEFSSDFGSWDKCKFYVNKYLVNNICAFDPTAKHVEVNVQLIDEYIRDHSRTEVWKFGNVVIEHLYHWIHICSALMKITKQLNSGITPPLPSKTDNYMYAKMPGEGLQEK
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 5.
Protein: PA_I68A3
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKGNRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLKLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNVVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPEPRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: GSHB_ECO27
Sequence: MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMADLYLINGEARARTRTLSVEQNYDKWYEFTGEQDLPLADLDVILMRKDPPFDTEFIYATYILERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILKPLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEPVPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIGDRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: RL9B_YEAST
Sequence: MKYIQTEQQIEIPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNGDRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFIVEDM
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L9-B, L8, Large ribosomal subunit protein uL6-B, RP24, YL11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_SYNWW
Sequence: MTAKLEKIENSEAYIEIEVSAEQVEEGLQYAYRKVIKQVAIPGFRKGKAPRELLELQFGKEVLFQDALEYIVPEAYDKALEELNIKPIAQPEFDINDPESGQPFKFNARVPVKPEVKLGEIEGIEVEIPDFQVKEEDVIQKFEDMRQQYAQVVEKIEEPAAMGDKLNIDFEGFIDGEAFAGGKGEDYSLELGSNTFIPGFEEQLVGLKAGESKDVLVTFPESYHAEDLAGKDAVFQVSVKRIETTEARELNDEFAQEVSQFNTIDELRQDIRKNLEEMAESRRKESIKTELMEKALEKCDIPVPDAVINMQVERMLQDFEQRMAYQGLTLEQYFQFTNSNREDFSQKIWPEAEKSVKGDFMLEKLAEEKGMEVSEEELNEHIMKLANNFGMEVDKIKEELGDAIENIRTGLKIDKAIDFLIDKAVVKEVAEITAAAAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: HSLV_SYNWW
Sequence: MFQATTIIAVRKGQQTAIAGDGQVTLGQNTIMKQNATKIRRLYEGKVIAGFAGAVADAFTLFAKFEEKLKQAGGNLSKAAVEIAREWRSDRILRRLEALLIVADAEKIFIVSGSGELIEPDDGIAAIGSGGAYALAAARALNAFSELNAREIAVESLKIASGICVYTNEQISVEVIEK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_PSYCK
Sequence: MTASTATETLLHKGSGLQVVVGLGQSGLSVAHYLAEQGYQVAVTDNQENPALANKLPATIDIRQFGAIDAELLQQAARIIISPGISLDNVAIAAARAANIPVVSDIQLFCEACTVPIVAITGSNAKSTVTTLVGQMAADAGINVGVGGNIGVPALSLLSNKEMELAVIELSSFQLETVTNLGAQVATVLNMSPDHLDRHGDMLGYHQAKHRIFQGAKSVVINREDALTRPLVSDSLPRLSTGIHAPNKGHYGLITDTAGQTYLARGTERLISADKLKIKGRHNLLNAQAALALGELAGLPLEIMLITLQQFAGLEHRCQYVSTVAGIDYFNDSKGTNIGSTMAAVEGLGAVYAPKDGKLLLILGGQGKGQQFGELSPFINQYVSQVLFIGEDGKQIEQHLRAAGLSDEVSLHQCQTLENAFATIEQVTASSLSQVQAVLLSPACASFDQFDGFVARGEHFSQLVKQLDVVS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBGA_ECOLI
Sequence: MNLQRFDDSTLIRIFALHELHRLKEHGLTRGALLDYHSRYKLVFLAHSQPEYRKLGPFVADIHQWQNLDDYYNQYRQRVVVLLSHPANPRDHTNVLMHVQGYFRPHIDSTERQQLAALIDSYRRGEQPLLAPLMRIKHYMALYPDAWLSGQRYFELWPRVINLRHSGVL
What are the official names of this protein?
Uncharacterized protein YbgA, ORF169, TKP.
Protein: GSH1_ECOL5
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.