PharMolix/UniProtQA huggingface dataset:
Protein: MNMA_RHILO
Sequence: MNSLDLPGRPENTRIVVAMSGGVDSSVVAGLLKREGYDVVGVTLQLYDHGAATHRAGSCCAGQDIDDARRVSETLGIPHYVLDYEERFRKAVIDPFAESYVAGETPIPCVSCNQTVKFADLLATAKELGADALATGHYIRSGANGAHRALYRPVDADRDQSYFLFATTQAQIDYLRFPLGGLSKPQVRAIAEEMGLTVAAKQDSQDICFVPQGKYSDIIAKLKPAAANPGDIVHIDGRVLGRHEGILRYTIGQRRGIGIASGEPLYVVHLDAERARVVVGPREALETHKIYLRNMNWLGDGPLGDIPEGGLELFAKVRSTRPPRPAVLRYVAGVTSVELADGESGIAPGQACVLYSDDGNEARVFGGGFIERSERGAEAEAMLTKLAARPAQIPAE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_MYCBT
Sequence: MSASDGNTAELWVPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTEV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: Y3246_MYCUA
Sequence: MSGHSKWATTKHKKAVIDARRGKMFARLIKNIEVAARVGGGDPAGNPTLYDAIQKAKKSSVPNENIERARKRGAGEEAGGADWQTIMYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTRNGGAMADPGSVSYLFSRKGVVTLEKNGLTEDDVLAAVLEAGAEDVNDLGDSFEVISEPGELVAVRSALQDAGIDYESAEAGFQSSVTVPVDVDGARKVFKLVDALEESDDVQNVWTNVDVSDEVLAELDEE
What are the official names of this protein?
Probable transcriptional regulatory protein MUL_3246.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1467_SHESA
Sequence: MNKNDDKEGMAMFSALIEGIKPIAQDKRHFRTPLKTKQEIELKEQQLHADSYFSDTYQPLLPVQGPMRWLDEGVDSLELKRLRRGDYQPDLLLDLHGYRQSEAKLELAALIQACVKQQSQCCCVMHGYGTGILKQQVPMWLVQHPKVKAFHQAPKEWGGDAALLVLIDIGDQPHRR
What are the official names of this protein?
UPF0115 protein Shewana3_1467.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: NAGB_ARTS2
Sequence: MEVVILPGSKQIGALAADAIEALLRRKPDAVLGLATGSSPLPVYDELARRHGQAGLDFSRVQAFALDEYVGLEPGHPQSYREVIRREFTDRVNIAPGNVHHPDGSAADIPAACQAYEDAIKAAGGVDLQLLGIGTDGHIGFNEPGSSLASRTRIKSLIEQTRRDNARFFTNIHDVPHHVLTQGLGTIMDARHVILIATGAQKAQAVRDFVEGPVAAICAASVLQMHPHVTVLVDEAAASSLRLADYYRHTYDSKPAWQGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RL24_STRA5
Sequence: MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVVVEGVALIKKHQKPNNENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYNKKSGEVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RS19_METVS
Sequence: MARQKFSGKGGKGKSKKGQQSTAPRRRVEFKYKGFTLPELQEMPIKKFIEIVPARQRRTMSRGITPNQRKLVMKIKKARRLVNRGKEPRVIRTHCRDFVITPEMIGLTISIYTGKQFKEIKLVEETLGRFLGEMAPTRGIVQHGSPGMGATRGSMFVPIK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CLPD1_ORYSJ
Sequence: MEVCCCSTSSAVPGRRFAAAGAAAAAVAARWGAVGVGRAVVLAHPLRPAPRGGHAHAQQAGARRARRAVVRAVFERFTERAVKAVVLSQREAKGLGEGAVAPRHLLLGLIAEDRSAGGFLSSGINIERAREECRGIGARDLTPGAPSPSGSGLEMDIPFSGSCKRVFEVAVEFSRNMGCSFISPEHLALALFTLDDPTTNSLLRSLGADPSQLASVALTRLQAELAKDCREPAGASSFKVPKKSPAGAGRSAFSKSLNSKKEKGALDQFCLDLTTQASGGFIDPIIGREEEIERVVQIICRRTKNNPILLGEAGVGKTAIAEGLALRIANGDVPIYLVAKRIMSLDVGLLIAGAKERGELESRVTSLIREVREAGDVILFIDEVHNLIGSGTVGKGKGAGLDIGNLLKPPLARGELQCIAATTLDEHRMHFEKDKALARRFQPVLVEEPSQDDAVKILLGLREKYETYHKCKFTLEAINAAVYLSARYIPDRQLPDKAIDLIDEAGSRARMESFNRKKEGQSSILLKSPDEYWQEIRAAQNMHEVVSSNQMKYSPRQENGSAAIKAPSEDMNELTSELQVEEPIVVGTEEIARVASLWSGIPVQQLTADDRKLLVGLDGELRKRVIGQDDAVMAISRAVKRSRVGLNDPDRPIATLLFCGPTGVGKTELTKALAASYFGSESAMLRLDMSEYMERHTVSKLIGSPPGYIGYGETGTLTEAVRRKPFTVVLLDEIEKAHPDIFNILLQIFEDGHLSDSQGRRVSFKNTLIVMTSNIGSTSISKGRRSMGFMTEDTESSSYVAMKSLVMEELKAFFRPELLNRIDEMVVFRPLEKTQMLAILDIILQEVKGRLLALGIGLEVSDAMKDLICEEGYDKSYGARPLRRAVTHLIEDVISEAILFGEYKPGDTILMDIDAGGKLCMSHLNEKVVQLSDPTRTF
What is the function of this protein?
Molecular chaperone that may function in heat stress response.  May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast (PubMed:20141629).  Chaperone involved in response to abiotic stresses.  Plays a positive role during dehydration and salt stress (PubMed:27457985).
What are the official names of this protein?
Chaperone protein ClpD1, chloroplastic, ATP-dependent Clp protease ATP-binding subunit ClpD homolog 1, Casein lytic proteinase D1.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HUTG_SALTI
Sequence: MTQWYPASPALWQGRDDSIEAPDARRLFQTVTRSEAFFPENWQQKIALMGFACDEGVKRNSGRPGAAGGPDALRKALANMASHQGHERLVDLGNWVAPTPDLEGAQQALRDAVSRCLRAGMRTLVMGGGHETAFGHGAGVLDAFAQESVGIINLDAHLDLRQTDRATSGTPFRQLAQLCDAQSRAFHYACFGVSRAANTQALWREAQWRNVTVVEDLDCHDALAQMTQFIDKVDKIYLTIDLDVLPVWEMPAVSAPAALGVPLIQVLRLIEPVCRSGKLQAADLVEFNPRFDEDGAAARVAARLGWQIAHWWR
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: HYBF_ECOLI
Sequence: MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAVRFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPLCHGERLRVDTGDSLIVKSIEVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.  HybF is involved in maturation of hydrogenases 1 and 2.  It may partially substitute for the function of HypA and vice versa.
What are the official names of this protein?
Hydrogenase maturation factor HybF, Hydrogenase nickel incorporation protein HybF, Hydrogenase-2 operon protein HybF.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family. HybF subfamily.
Protein: HIS5_PROMA
Sequence: MILNIGLIDYGMGNLHSVEQSFKRLNQSLKIISGPNDLSNCDALILPGVGSFDPAMKNLQQTNLIPELKKWVLNNKPLLGICLGLQLLFESSDEGKSKGLGLLKGTIKHLPKSEKQLIPHMGWAELNQDKECPLFKSNSSPQWMYFVHSYSAIPSDKNDIASSVNFGDEKITAVVWKKKLAACQFHPEKSGRSGELLLSNWLAWLKKETKDLY
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YERH_BACSU
Sequence: MKKTLALAATAAVLMLSACSSGFGGEKEEEITQKTAKSSEKAIVPKYNISDSYYKMVLPFKAGKARGLTTEQLNTRLDIDEFETGLMRLAQDSFSTDDYLFQEGQYLDEDTVLSWLARKKTGSDLKKAEKEDKNFKNEGLNPALPSSGSTEEKNESSPIYLASMLEHDYLVRKDKNSIQLGGVMIGLALNSVYYYREKTGDPQKEVEIKDSTLRQQGEKIAQEVINRLRKKDNLKNVPITVALYKQASKTSIVPGNFIAKTEVKAGSTDISNWDDINEKYVFYPADTTTAEKYPDDTEVFKRFKNSIEEYFPNYTGVVGTALYENDEMKKMKIDIPMQFYGKSEVVAFTQFLTGEVMDYYSKSSVDVEVNITSSDGQEAVIIRNAGDKEPTVHIYD
What are the official names of this protein?
Uncharacterized lipoprotein YerH.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane raft. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: Y124_THEMA
Sequence: MKIVEVKNLTYRINDFEILKNVTFSVEEGEFVGIIGPNGAGKTTLVRILVGDIKNYEGKVEVRGKIGYLPQLHQVQREFPITVKEFAAMGMYGRYRKIDWEKVRSTLKDVGILHKENDPIKNLSGGEFQRLSLARALLSDPDILVLDEPEAGVDEMGKASFYELLNRLRKEKNITVIMVSHDIGMVFKECSTIMCLNRTLHCHGPTETINPEDLKKIFTDFDIWIRGTRHYEIYHGRERD
What is the function of this protein?
Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Probable metal transport system ATP-binding protein TM_0124.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: APAH_ECOSE
Sequence: MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEAAAS
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: ALR_FUSNN
Sequence: MRTWIEIDKENLKYNVLKLKEIANNKEILGVVKANAYGLGSIEIAKILKEVEVKLFGVANLEEAIELQEAGIKDKILILGASFEDELVEATKRGVHVAISSMGQLQFLVSKNLNPNIHLKFDTGMTRLGFEVDDAEKVIEYCKNNNLNLVGIFSHLSDSDGNTIETKNFTLEQIEKFKKIVNSLNLEYIHISNSAGITNFHNDILGNLVRLGIGMYSFTGNKKTPYLKNIFTIKSKILFIKKVKKDSFVSYGRHYTLPADSTYAVLPIGYADGLKKYLSKGGYVLINNHRCEIIGNICMDMTMIRVPKEIENSIKIGDEVTVINADILDNLNIPELCVWEFMTGIGRRVKRIIV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PANC_RUEPO
Sequence: MSAPILRKLADLRAATAGWKRAGESIGVVPTMGALHDGHLSLVAAAKAGCDRVVVTIFVNPKQFNNPEDLAKYPRTELADASKLAPYGVDAIYVPDPDQIYPEGFATTVSVSGLTDVMEGACRPGHFDGVATVVAKLFLQTGADQAYFGEKDYQQMMLVTRMAQDLDIPITVVGCPTVREASGLAMSSRNMRLSAEGLERAGRLHPVMRQVAERLAAGASFGDLAPGAREALGAAGFVDIEYFDLRAADSLRALDRPTEPARLLVAAWLDGVRLIDNIAVSQLND
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAT3_NEUCR
Sequence: MRVNALLPLSGLIGTALAACPFADPSALGRRAEGGEVDARQRLKEVEVDDNGQFMTTDFGGNIEEQFSLKAGGRGSTLLEDFIFRQKLQHFDHERIPERVVHARGAGAHGIFTSYGDWSNITAASFLGAKDKQTPVFVRFSTVAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAIRFPDLIHSVKPSPDNEVPQAATAHDSAWDFFSSQPSALHTLFWAMSGNGIPRSYRHMDGFGIHTFRLVTEDGKSKLVKWHWKTKQGKAALVWEEAQVLAGKNADFHRQDLWDAIESGNAPSWELAVQLIDEDKAQAYGFDLLDPTKFLPEEFAPLQVLGEMTLNRNPMNYFAETEQISFQPGHIVRGVDFTEDPLLQGRLYSYLDTQLNRHRGPNFEQLPINRPVSGVHNNHRDGQGQAWIHKNIHHYSPSYLNKGYPAQANQTVGRGFFTTPGRTASGVLNRELSATFDDHYTQPRLFFNSLTPVEQQFVINAIRFEASHVTNEQVKKNVLEQLNKISNDVAKRVAVALGLEAPQPDPTYYHNNVTRGVSIFNESLPTIATLRVGVLSTTKGGSLDKAKALKEQLEKDGLKVTVIAEYLASGVDQTYSAADATAFDAVVVAEGAERVFSGKGAMSPLFPAGRPSQILTDGYRWGKPVAAVGSAKKALQSIGVEEKEAGVYAGAQDEVIKGVEEGLKVFKFLERFAVDGDDEE
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase-3.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: YABA_STRZT
Sequence: MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLENSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELLYRE
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: SOCA_CAUVN
Sequence: MPPLTQDPQSVDARAVANLLLDKAAALDIPISNLALQKLLYFAHGRFLVDKGRPLVNGFFEAWKFGPVHPVVYRCFSANGPKYIINRAIKKDILSGLHIIVSPPRDQDIHEGIERVLLTMGRMSASQLVAVSHASGGPWDVIANGPGTNLGLGLRICDKVIKDRFRFQKVSVSVPPGLGDTLEEAPPS
What is the function of this protein?
Antitoxin component of an atypical type II toxin-antitoxin (TA) system.  Unlike most type II TA systems, neutralizes the toxic activity of cognate toxin SocB by acting as an adapter to promote its degradation by ClpXP; degradation is dependent on the N-terminus of ClpX.
What are the official names of this protein?
Antitoxin SocA, Adapter protein SocA.
Protein: MTNC_SHEHH
Sequence: MGIRAIVVDTAGTTTDLNFIEEILFPYSAKALPAFLEENQHNVLVENCICDVQDIALEPDASLARVTEILLQWIKEDRKATPLKTIQGLIWKQGYANGEFKGHIFPDFIEALDGYKQQGLRVYSFSSGSVEAQKLLFSHSDAGDLNDKFNGHFDTRTGNKRFKQAYCNIVNTISLSPKQILFVSDVLEELKAASEAGLNVVQMVRDDSQRTGDFKTISSFAELSI
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: RIPL2_XENTR
Sequence: METEQDEVAQDELGPEIALDKDPFQLTVEDVYDISHIVGQDLLKISREARGVSSLVSDLQFKIVRVLEMLEALVNQSSLSAEELKMERDNLKAEVERLLKDGPQMGVGPDKMVIDLTDPNRPRFTLQELRDVLQERNKLKVKLLVAQDELQCYKSGIIPSPDDQIVTLENESMITCSPRENESKEKSTVKSLFSFKQGKQT
What is the function of this protein?
Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines.  Plays a role in cellular protein transport (By similarity).
What are the official names of this protein?
RILP-like protein 2, Rab-interacting lysosomal-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the RILPL family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.
Protein: RSAD2_BOVIN
Sequence: MWMLVPIAFALKLLNVFLQPLGSVWSSLGPLFLQLRAASWLAGGERSRPLQDRREAGEPGRAEGEDGGDLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKKGLLMLKEAGMEKINFSGGEPFLQDRGEYLGRLVKFCKQELQLPSVSIVSNGSLIRERWFQKYGEYLDILAISCDSFDEQVNVLIGRGQGKKNHVENLQKLRTWCKEYRVAFKINSVINRFNVDEDMKEQITALNPVRWKVFQCLIIEGENSGEDALREAERFVISDEEFEAFLDRHKDVSCLVPESNQKMRDSYLILDEYMRFLNCRNGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW
What is the function of this protein?
Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon.  Catalyszes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP) via a SAM-dependent radical mechanism.  In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication.  Therefore, inhibits a wide range of DNA and RNA viruses.  Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6.  Plays a role in CD4+ T-cells activation and differentiation.  Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities.  Can inhibit secretion of soluble proteins.
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2, SAND, Radical S-adenosyl methionine domain-containing protein 2, Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible, Viperin.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RSAD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Endoplasmic reticulum. Lipid droplet. Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane.
Protein: NNJA1_WHEAT
Sequence: MASRDFLGRFGGEKGAASDKAGGGAGEADEVAELSLGLSLGGCFGANSGRDAKKPRLVRSSSLAAMCSLPGTSDDLAAATPPPAPLMRTSSLPTETEEERWRRREMQSLKRLQAKRKRLERRTSMNSGKSGGSSSRDDAQEPLYPSAFQLRRSVVDQGNPSSSMPEQGSGDGAEVKSTSSMEISSDNNNNASNQNKSLPPPAPSPAAGKLPNGIVKEQPPLRTLRSLTMRTTSTGDLRKSMMEDMPMVSSKVDGPNGKKIDGFLYKYRKGEEVRIVCVCHGNFLTPAEFVKHAGGGDVTNPLRHIVVNPSPSVFL
What are the official names of this protein?
Ninja-family protein 1, ABI five-binding protein A1, ABI5-binding protein A1, TaAFP-A1.
What is the protein family that this protein belongs to?
Belongs to the Ninja family.
What are the subcellular locations of this protein?
Nucleus.
Protein: G37L1_HUMAN
Sequence: MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
What is the function of this protein?
G-protein coupled receptor (PubMed:27072655).  Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade (PubMed:23690594).  However, other studies have shown that prosaposin does not increase activity (PubMed:27072655, PubMed:28688853).  It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha (PubMed:27072655).  Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway (By similarity).  Regulates baseline blood pressure in females and protects against cardiovascular stress in males (By similarity).  Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity (By similarity).
What are the official names of this protein?
G-protein coupled receptor 37-like 1, Endothelin B receptor-like protein 2, ETBR-LP-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Note=Associates with the basal membrane of Bergmann glia cell primary cilia.
Protein: NS1_I78AC
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTFEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPPLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: RS16_BACLD
Sequence: MAVKIRLKRMGAKKSPFYRIVVADSRSPRDGRFIETVGTYNPLAKPAEVKIDEELALKWLQTGAKPSDTVRNLFSKEGIMEKFHNAKQSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NU5C_VITVI
Sequence: MEHTYQYAWIIPFLPLPIPMLLGVGLLLFPTATKNLRRMWSFTSVLLLSIVMTFSVNLSIHQINSSSIYQYVWSWTINNDFSLEFGYLIDPLTSIMSILITTVGIMVLIYSDNYMSHDQGYLRFFAYMSFFNASMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGLYWITGSFEFRDLFEIFNNLIYNYNNGTNFLFVSLCALFLFVGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLFPLFIVIPYIMNLISLIGIITILLGATLALAQKDIKKSLAYSTMSQLGYTMLALGMGSYRAALFHLITHAYSKALLFLGSGSIIHSMEAIVGYSPDKSQNMVLMGGLTKHVPITKNTFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIACLTAGLTAFYMFRIYLLTFEGYFNVHCKNYSGKKSSLFYSISLWGKEGQKTIKKKIRLLTLLTTNNNENEKASFFSKKVYRLDSNVRKMTRPFITINQFDNKNTFLYPQESDNTMLFPLFALALFTLFVGAIGIPFNQERMDFDILSKWLNPATNLLHKNLNNYGDWYEFVINAIFSVSISYFGIFLASLLYNPVYSSLQNLDLINSVAKKVPKRIFWDKIINKVYNWSYNRGYIDAFYETSLTKGIRGLAELTHFFDGRVIDGITNGVGVTSFFVGESIKYVGGGRISSYLFLYLSSVSILLLISYFFLNQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MPPA_MOUSE
Sequence: MATAVWAAARLLRGSAVLCARPRFGSPAHRRFSSGATYPNIPLSSPLPGVPKPIFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVDLLADVVLHPRLTDEEIEMTRMAVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPVENIAKIDREVLHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLVGAEPAWGAPGTVDVDRSVAQYTGGIIKVERDMSNVSLGPTPIPELTHIMVGLESCSFLEDDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLRGKPAVAALGDLTDLPTYEHIQAALSSRNGHLPRSYRLFR
What is the function of this protein?
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
What are the official names of this protein?
Mitochondrial-processing peptidase subunit alpha, Alpha-MPP, Inactive zinc metalloprotease alpha, P-55.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion inner membrane.