PharMolix/UniProtQA huggingface dataset:
Protein: GLO2_NOSP7
Sequence: MQVIRLEALSDNYIFLLYDDKRNIAAVVDPAEAQPVLKKLAELKADLVAIFNTHHHNDHVGGNKQLIEKFPQLIVYGGAEDRGRIPGQKVFLQQGDRVEFADRIAEVIFVPGHTRAHIAYYFPPQEASETGDLFCGDTLFSGGCGRLFEGTPTQMVDSLSKLRSLPDNTRIWCAHEYTLKNLQFALTVDGDNADLQRRFNEVKAYRSRGEATIPSLLGVEKHTNPFLRWDQASLQSTVKSSDGVQTFARIREMKNNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: F246C_HUMAN
Sequence: MAEPGRPWAQARSAYRASEVLRRGTGRRRDPGPQSNGPGQEDARAPGRMARLRGQLRAEAASRSEVPRLLKLVERAGAGAAGRGREDRRAQPRAPCARYAGSPAAGPPTRRGSWRSASGGCRRAWRQCARSWAPGLRRCARSFERSWMPCARCCRRRRPRLPAASPAPSPAPRPAARPCRGRSAPLAPWSPPPGPQTTPRTAQQNAERTEPRPGRTTRRCQCRLGPRKVAGTEGGRTRAA
What are the official names of this protein?
Protein FAM246C.
What is the protein family that this protein belongs to?
Belongs to the FAM246 family.
Protein: RS10_FRATF
Sequence: MAINNQRIRIRLKAFDHKLIDISTQEIVDTAKKTGAQVKGPIPLPVRKEKFTILISPHVNKKARDQYEIRTHKRLIDIVEPTDKTVDALMKLDLASGVDVQISLS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CAHS2_PARRC
Sequence: MEAMNMNIPRDAMFVPPPESEQNGYHEKSEVQQTSYMQSQVKVPHYNFPTPYFTTSFSAQELLGEGFQASISRISAVTEDMQSMEIPEFVEEARRDYAAKTRENEMLGQQYEKELERKSEAYRKHQEVEADKIRKELEKQHMRDIEFRKEIAELAIENQKRMIDLECRYAKKDMDRERTKVRMMLEQQKFHSDIQVNLDSSAAGTESGGHVVSQSEKFTERNREMKR
What is the function of this protein?
CAHS proteins are cytosolic heat soluble proteins that seem to contribute to the anhydrobiosis in tardigrades, but their specific mechanisms are yet to be identified (PubMed:28306513, PubMed:33545053).  It is possible that protection during anhydrobiosis might occur via the stabilization of vitrifying small molecules such as sugars, but not via the direct glass transition of CAHS proteins themselves (Probable).
What are the official names of this protein?
Cytosolic-abundant heat soluble protein 106094, CAHS 106094, Tardigrade-specific intrinsically disordered protein CAHS 106094, TDP CAHS 106094.
What is the protein family that this protein belongs to?
Belongs to the Cytosolic-abundant heat soluble protein (CAHS) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOX22_HORVU
Sequence: MQTATKPLVGARAVPLSRRASFLVAEARRKPSTNARRTRVGSTSTTTTTTTILTDVNGPALTTVAKPGHQYDLKQTVEMKATVSVHMKSFWWSDEKKERARDWAYDLILGSWLTLELVSSELDPKTGQEHDVISGKLKHSRETEKDYDLYEAIFTCRHRLAPSGAVRLVNYHHTEMLLGEVKIFPAGEDPTKSSAVTLFHCQSWIDPSHCSPDKRTFFPVEKSYIPSQTPKGVEKLRKSELEALRGNGCGERKKHDRIYDYDVYNDLGKPESKRPVLGGKEHPYPRRCRTGRPRSKTDPSSEEESHKKGEMYVPRDETFTERKEQAFLTKQLLSQLHGLCTGLKVNKDILPSFPTLASIDALYDDDFRNQPVQPEGGKVRLILDLLAKELVHLVKLEGAEFVEGIRRVFKFETPEIHDMDKLAWFRDEEFARQTLAGMNPLSIQLVTELPIVSKLDELKYGPADSLITKELIEKQINRIMTAEEAVAQKKLFMLDYHDLLLPYVHRVRKLDNKTMYGSRTLFFLADDGTLRPIAIELTRPKSPHKQQWRKVFTPGSGYSGSVTGSWEWQLAKIHVLSHDTGYHQLVSHWLRTHCCVEPYVIAANRQLSQMHPIYRLLHPHFRFTMEINAQARGMLICADGIIEKTFSPGEFSMEISSAAYDKQWRFDMEALPEDLIRRGMAVRGEDGKLELAIEDYPYANDGLLVWDAIKQWASDYVAHYYPCAVDIVDDEELQDWWTEVRTKGHPDKQDEPWWPELDCHESLVQVLATIMWVTSAHHAAVNFGQYPMAGYVPNHPSIARRNMPCEMGPEEMLAFKAAPEKVWLDTLPSQLQTVMVMATLDLLSSHASDEEYMGTHQEPAWQRDGEVDKAFQVFQKKMRDIAEQVEEWNKDDSRRNRHGAGVVPYVLLRPLNGNPMDAKTVMEMGIPNSISI
What is the function of this protein?
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  This enzyme exhibits linoleate 13-lipoxygenase activity.
What are the official names of this protein?
Lipoxygenase 2.2, chloroplastic, LOX2:Hv:2.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ETR4_ORYSJ
Sequence: MAMVTARQFLASAAELGSGRRRCGGGGACDMREDGGVEALMQCQRVSDLLIAASFLSIPLELFYFATCADLSEVKCAVLHFCAFIVLCGATHLLAAFTHAHPHSAPLLRALTAAKVLAAVASSAAAVSLLTFIPKLLRIKVRESLLRDKASRLHRDLGLVRRREEATSRAVRELTGRIRASPPDAHAILRTTALQLADALGLHACAVWMPAAGRPHDLVLVHHLTSRPDDAADLLLEVGDACTVAADDPDVVDVMASKVAKVLGPDSALAMASSVGAAPAGAVAAIRIPILRVSIYDGGGTPEVTEASYAILVLLLPPHDAAGGWSSHDLEIVQVVADQAAVALSHAAVLEESRSMRDRFAEQHRALMQAKHRAAMATRAFSSIQSAMCHAMRRPVHSVVGLVSMLQHPEADTMRPEQRLAVDAIARTSNLLSALMDEVTVNRQHLSVQRKPFSLHALIKEAISVAGCLSHCGGAGFLHQPECALPEWVVGDERRVFHLLLDMVGTLLNRCNTGSGACRLSFSVRICNVGEERYSLDWIPMRPTFSGCNVCVKFKVGIGRSRSCAIERSLPCELPRRSAATTSSQMGHIFSGYFNKIVQMMNGNMWSASDSEGVGESVTLILQFKLQQGHVEASPPYIPHLNGLRVLLADDDAMNRGVTKKILERLGCQVMSAPSGAHCLSLLASAEASFQLVVLDLDDRAVPSAAMDRFEVALRIRELRNSCWLLIVIAVAAGVVATDDGGAVQELCQRAGINGLVQKPVTLPALGAQLCRVLQDN
What is the function of this protein?
Ethylene receptor related to bacterial two-component regulators.  Acts as a redundant negative regulator of ethylene signaling.
What are the official names of this protein?
Ethylene receptor 4, OsETR4, OsPK3.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TAT_SIVV1
Sequence: MDKGEEDQDVSHQDLIKQYRKPLETCTNKCFCKKCCYHCQFCFLRKGLGITYHAFRTRRKKIASADRIPVPQQSISIRGRDSQTTQESQKKVEEQAKANLRISRKNLGDETRGPVGAGN
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: H32_MEDSA
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRFRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVSALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2, Histone H3.1, Major histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MINE_LARHH
Sequence: MSLIEKLFGKRQKTASIARERLQIILAHERNGRAEPDYLPQLQQELIAVISKYVKIAPEDIKVQLERQDDLEVLEVNIVLPEPQQRTVA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SYF2_ASPFU
Sequence: MPAECVNEVSAAKPSDDNAASNQTQSGAAPAEPAASEEPQQKTSSEKLESKEDDAAAKARQRQERFKALQARAKNAAERNLKETAAETQRLATDPALLSSLSRKHAFASHNLLKADTEAAGEDFERKRAWDWTIDESEKWDRRMEKKQRHRDDVAFQDYTQDARKVYKRQLRQMQPDMAAYEREKLAAIEKAAANGDLEIVETNDGEMIAVDKNGTFYSTADTIGFTENKPDRAGVDKLVADLRKAEEVRLKKRRERRGDEEPDVTYINEKNKQFNQKLARFYNKYTTEIRDSFERGTMI
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor syf2.
What is the protein family that this protein belongs to?
Belongs to the SYF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATP62_CHLP8
Sequence: MRVKANSKILALIVPVLLSLNSLVCANPVQEDMSAHESLPAAAAPAEVHAPVEVHNAAGTHVETAHESAVEGHEEKAGDVIMHHVQDSNVLAFEPFGEIELPHLQLGSLDISITKHVVMMWVAAVILILVGAAAGAGVKKISVKQAPSGIANVMEALVDFIRLDVAKSNIGHGYEKHLPYLISVFFFILVCNLLGLIPYGATATGNINVTLALSIFTFFITQIAAFKELGVGGYVKHLTAGTHWSLWIIMIPIEIIGQFTKPVALTIRLFANMTAGHIIILSLIFISFILESYIVAAAVSVPFAIFIYLLEIFVAFLQAFVFTMLSALFIGLATAHESHDSHELEASGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 2, ATP synthase F0 sector subunit a 2, F-ATPase subunit 6 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: S31A5_HUMAN
Sequence: MENLPFPLKLLSASSLNAPSSTPWVLDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSPGKRKCPVGRRRRPRGRMKNHSLRAGRECRRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEPMEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVPQSLSPHEDLVASVPAISGLGGSNSHVSASSRWQETARTSCAFNSSVQQDHLSRHPPETCQMEAGSLFLLSSDGQNVVGIQVTETAKVNIWEEKENVGSFTNRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGENSKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFNEMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTSQAKGKPSPWQSSMSTGEGSKEAQKVKFQLERDPCPHLGQILGETPQNLSRDMKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTHIENILKAHMGRNLGQTNEGLIPVCVRRSWLAVNQALPVSNTHVKTSNLAAPKSGKACVNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSATCESGAGSEVEVDMFLRKPPMASLRKQVLTKASDHMPESLLASSPAWKQFQRAPRGIPSWNDHEPLKPPPAGQEGRWPSKPLTYSLTGSIQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDVHGFEAPGTSKSSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVHEEPRNPNCQGSCKSQRPMFPPIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKKQPPSVSPFGENIKQIFQWIFSKKKSKPAPVTAESQKTVKNRSRVYSSSAEAQGLMTAVGQMLDEKMSLCHARHASKVNQHKQKFQAPVCGFPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQIRNQQPLKSVRCNNEQWGLRHPQILHPKKAVSPVSPPQHWPKTSGASSHHHHCPRHCLLWEGI
What is the function of this protein?
May play a role in spermatogenesis.
What are the official names of this protein?
Spermatogenesis-associated protein 31A5, Protein FAM75A5.
What is the protein family that this protein belongs to?
Belongs to the SPATA31 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TSAC_XANC8
Sequence: MPHTPDLDAAVATLARGGVIAYPTEAVWGLGCDPRQEDAVLRLLEIKRRPVDKGVIVVASGLDVLQDWIDIAALGSEQLTAVLAQWPGPHTWILPVTAQAPRWVTGDHDGLAVRISAHPVVAALCKAWGAPLVSTSANLAGEPPARSRAALDPALLARIDGVLDGEVGGLAQPTPIRDARTGQILRD
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXO_DROER
Sequence: MMDGFAQDWPTLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALDELTGTMADELTLCPQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQSPYALNGPAPGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQMSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNLSNISNISNISSNSGSSLSLNQLQAQLQQQQQQQAQQQQAQQQQQAHQQHQQQLLLNNNNNSSSSLELATQTASANLNARVQYSQPSVVTSPPSWVH
What is the function of this protein?
Transcription factor involved in the regulation of the insulin signaling pathway.  Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR.  Involved in negative regulation of the cell cycle, modulating cell growth and proliferation.  In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.  Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging.  Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis (By similarity).
What are the official names of this protein?
Forkhead box protein O.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation (By similarity).
Protein: MECA_ALKPO
Sequence: MDIERVNDTTIKFFITYKDIEDRGFDRDEIWYNRERGEELFFEMMNEANDRDEFELDGPLWIQVHALDKGLEIVVTRGQVSDGNVKLEIPVSQDKENTDENIVDLMTGHSSEDDEGIDTDQLEIVIGFNDFEDIISLSHNFFIDDLENELYHFEGRYYLHVLFNDDQYNEDEQDDMLSQMLEYGYETDLSIHRMQEYGKEIIGEYALKHLRGHFPQN
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.  Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease.  When overexpressed, inhibits sporulation.  Also involved in Spx degradation by ClpC.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: DNJ2_CAEEL
Sequence: MRSAIAAPILFLLVSFFVQECESVGFAPELYCGLENCYDVLEVNREEFDKQKLAKAYRALARKHHPDRVKNKEEKLLAEERFRVIATAYETLKDDEAKTNYDYYLDHPDQRFYNYYQYYRLRAAPKVDLRIVIVGTILIISLFQFLSAKHKFSEAIEYATGVGKFRNMAIKDGIDKGLLEMDRNGKLKKNKGVDNDEVIKQIIIDNLDVTGGYKRESIYDTLAWHTIIFPLTIFRYIKWTALWYWRFAIQKEEYDDDAKLYLIRKYIGVSQMEFDQKYTDEDIDDLFERECWLKRNCATWKAERDAAEQEKMAQSGRYKRYKRYMKNAGTISFVDED
What are the official names of this protein?
DnaJ homolog dnj-2, DnaJ domain protein 2.
What is the protein family that this protein belongs to?
Belongs to the DNAJC25 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL7_THIDA
Sequence: MAVAKADILDAIAGMTVLELSELIKEMEDKFGVSAAAAAVAVAAPAAGAGAAAAAEEQTEFTVMLNSAGEKKVEVIKVVRAATGLGLKEAKDLVDGAPKAVKEGVSKADADALKKQLEEAGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: COX42_THUOB
Sequence: MLRLTAGRVRSLLAGRATAAFSTSSARMASHDLEVAESVDMSKPLYWDRLDTPLPDRPYKEDLTAADKSLKQKEKGPWGQLSKEEKIALYRLMFCQTYSEMKQPSSEWKTVFGGIFIFLGFTGLVVWWQALYVYPPRPRTFDDEWKAKQLKRMLDMRVNPIEGFSAKWDYEKGQWK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial, Cytochrome c oxidase subunit IV isoform 2, COX IV-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: MENH_ESCF3
Sequence: MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTGLLRKTLVSYNILNFWLVGYSLGGRVAMMAACQGMPGLCGVIVEGGHPGLQSAEQRAERQLSDRQWAQRFRSEPLTAVFTDWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNTHRENPAGVIASLAQILRF
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: METK_STRPM
Sequence: MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTKAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVEAVKTVL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_XANC8
Sequence: MRLTALPAFDDNYIWALVANDGRAVIVDPGQAAPVLEAAQREGFTPVAALLTHHHADHIGGVAELQQHFPALELYGPDDERMPSATRHVAHGDTVTALGIDFAVLEVPGHTRSHVAYVGDGHLFSGDTLFSLGCGRMFEGTPPQMFDALQRLASLPGETLVCCGHEYTLANAAFALHVDPTNAALQRRQQEAQAMRHAARPTLPISLKSELATNPFLRLHTPEIRAAAAAHASISITSDVDVFAELRRWKDAFRA
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: PRSA_CLOBH
Sequence: MKSAKKLLSVLCLGIFILTFTACDMVEKTPEAKAKSTIAKVNGEKIQRKDLDESPSMQQVLSQIKTQYGEEFEKSEQGKEVIKEQKKQILENLITEKVLLQKGKELKVIPKDEELNKEADKKVNEIKAVYNNDEKKFEETLKSTGFTKETLKEYLRDQIVIEKVINEVTKDVKVEDKDAQKYYNENQSMFTEKPNTMNVSHILVKTEDEAKKVKKRLDAKEDFAKVAKEVSQDPGSKDKGGLLGDISYSDSNYDPTFMKAAIALKEGTISNPVHTQWGYHIIKVNSKKEYPVKKFDSVKEDIKKQLKQEKQQEAYTKKIEEWKKASKIKTYEKNLL
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ECFA1_STRPF
Sequence: MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGSGKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDDVAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPKIIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQVESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPIDYGYLTEKELENQLCQLISKM
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EI3EA_DANRE
Sequence: MAEYDLTTKIAHFLDRHLVFPLLEFLSVKEIYNEHELLHGKLDLLSDTNMVDFAMDVYRNLFPDKEIPNSLREKRTTVVAQLKQLQSETEPIVKVFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALNSLWGKLASEILMQNWEAAMEDLTRLRETIDNNTVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIELFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDSAQKKLRECEAVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISIGMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAISPYQQVIEKTKSLSFRSQMLAMNIEKKQSNANRNETPNWAAQDAGFY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E-A, eIF3e-A, Eukaryotic translation initiation factor 3 subunit 6-A.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL17_MYCTA
Sequence: MPKPTKGPRLGGSSSHQKAILANLATSLFEHGRITTTEPKARALRPYAEKLITHAKKGALHNRREVLKKLRDKDVVHTLFAEIGPFFADRDGGYTRIIKIEARKGDNAPMAVIELVREKTVTSEANRARRVAAAQAKAKKAAAMPTEESEAKPAEEGDVVGASEPDAKAPEEPPAEAPEN
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RS7_HELHP
Sequence: MRRRKAPVREVLGDPIYNNKVVTKFINKMMLDGKKSVSEKIIYAAFDKIEEKSGEKGIEVFEKALERVKPLVEVRSRRVGGATYQVPVEVRPARQQSLSIRWLLEATRKRNERTMIERLASELVDAANERGAAFKKKEDVHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.