PharMolix/UniProtQA huggingface dataset:
Protein: INPC_EMENI
Sequence: MIFTPPVWGPEMMAIPASRPIHEFLVERDSRHLYDWSEEKPALTIADRVDALARSLGRELGWSPNTGSPWSKVVGIFSFNTLDFLVASWAIHRIGGICMLMHPTSSAAEIKRHIELTECRVLFTCRSLLPTANEVLVASKVQDPRAYLLDLPEELGRKPSLPDQGQQTVEQLISAGATLPLIEALDWAEGQGKEQVAYLCPTSGTSGLQESALTVKKLAMITHYNIIANIIQATTFEAGPKKGRTEVALGFLPLSHSYGLILAHLTAWRGDTYILHARFDMQAALASIEKYRIERLYLVPPIISALVNNPFLLDLCDTSSVTSVVTGSGPFGPRLAEALSRVRPSWQVLPGYGLTETAVIISITDPNITYPGADGCLVPGVEARLINSNGNEVEAYNEPGELLLKSPSIMKGYLGQETATREVFDEQGWLRTGDIAVFRLTGQDGKVTPHLDIVDRKKDIMKVKGLQVAPVEIESHLAAHPAVAEVAVVGVRDEDAGERPYAFIVRSPRTMADLDEEALKADLNRHVEATLSEPHWLRKNIRFVEEFPKSSNGKPLKYKLKESLATSYARKTSPAIPNNTRNR
What is the function of this protein?
Acyl-CoA ligase; part of the inp gene cluster that mediates the biosynthesis of fellutamide B, a mycotoxin that acts as a proteasome inhibitor (PubMed:20952652, PubMed:27294372).  In the first step of fellutabmide B biosynthesis inpC activates 3-hydroxydodecanoic acid to generate 3-hydroxydodecanoyl-AMP that is then loaded onto the T0 domain of inpB (PubMed:27294372).  The 3-hydroxydodecanoyl-S-phosphopantetheinyl-T0 is sequentially extended with L-Asn and L-Gln by the two CAT modules of inpB (PubMed:27294372).  The linear lipodipeptide from inpB is then transferred onto inpA for the addition of the third amino acid, L-Leu (PubMed:27294372).  Reductive releasing of the lipotripeptide by the TE domain of inpA produces (2S)-fellutamide B (PubMed:27294372).  InpF might be involved in the release and transfer of the lipodipeptide from inpB to inpA (PubMed:27294372).  The inp cluster-encoded proteasome subunit inpE confers resistance to internally produced fellutamides (PubMed:27294372).  The MFS efflux transporter inpD may contribute to fellutamide resistance as well (PubMed:27294372).
What are the official names of this protein?
Acyl-CoA ligase inpC, Fellutamide B biosynthesis cluster protein C, Inp cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PIP_RAT
Sequence: MQGLSFTSTAATFFLVLCLQLGINEGQDNETIPQPLLFQLNVPSTPDENQEVDMSLTLQTQYKECLVVKAYLISNTPVDGGFNYIQTRCICNDHPTTLYWTFVVTQTLTFRIMVDIVKDKGICPNNVAVVPISGNRYFTDRTVYVN
What are the official names of this protein?
Prolactin-inducible protein homolog, Prolactin-induced protein.
What is the protein family that this protein belongs to?
Belongs to the PIP family.
What are the subcellular locations of this protein?
Secreted.
Protein: MICA_EMENI
Sequence: MVGSVVEAHRQSVGCLRNLSQLLAWASNTSGGLIFYSREDDVLTSTRISYAELLADAGEKARLIGQITGLSSESIILLHFDTQREVIEWFWAATLAGYLPAISTPFVDDTARRKAHLLHLHAQLNQPVVLTSKRLVPEFLGLEELRLHDVESLLSSAAKDGLIQYLGVQKLAEDVAVLMLTSGSTGSAKAVPLRHGQLLTAIQGKSTHHGTLPGDVFYNWVGLDHVASLTEIHLHALILGSDQVHTAASELLRNSLQFVRLLDTHKVAYTFAPNFFLTKVLDSLRENPTFTADLSSLKALISGGESNVVVTCDKLTRELRRRGVQAEVIRPGFGMTETCAGSIYSRACPSYDIRQSLEFASLGSCIPGMHMRIMSITEPGKLAAPGESGELQVAGPVVFDHYYNDETATRNAFTPDGWFITGDLGWIDDAGNLNLAGRTKDTIIVNGVKWSSTELEAAIEEEAVSGLVRSFTVVVPTRPPGSATEEIAVVYSPAYAPEDYHARYETAQVISKTVSLLTGTKPARLIPLPQSLLEKSSLGKISHSKVRAALESGEYASIERADQLILAQYRQFKWRPAKSDSERAVQKALVEFLQVPAEGINMDDSIYDLGVSSLNLILLRSTLQRMLDPKIDIPLSIILNNPTPGAIARSIDSSRSSLAGYNAIVPLQQHRHGGTPLFCIHPGSGEVLVFVALAAHFPTRPVYALRTRGYGSNEQLFGSIEETVETYATQIRQVQPHGPYAIAGYSLGSTLAFEVAKVLEAQGEEVKFLASIDYPPHIAHYVRDLNWTDVLLHIAFFLELIDEKTMVEVTPYLHTLDRQTALTHILNIGDAERARALAIDTKHLGLISDIAENFRVNVKTYKPQGKVQHLDVFVADPPTYAARDRKDWRENKLGRWVDFCETKVEFHDCPGIHAKMLNREHIAGFAKVFKAAMRRRGV
What is the function of this protein?
Microperfuranone synthase is the only protein required for the biosynthesis of the secondary metabolite microperfuranone from phenylpyruvic acid (PPA) (PubMed:22627757).  Several steps for the microperfuranione biosynthesis have been proposed (PubMed:22627757).  These steps include the activation of PPA, by the micA adenylation (A) domain to AMP-phenylpyruvic acid followed by loading of the PPA unit to the thiolation and peptide carrier (T) domain and eventually transferring to the thioesterase (TE) domain (PubMed:22627757).  After loading another PPA unit onto the T domain, aldol condensation establishes the carbon-carbon bond between the alpha- and beta-carbon of the two PPA units (PubMed:22627757).  Sulfur-assisted furan ring formation, TE domain mediated hydrolysis, decarboxylation, and keto-enol tautomerization would generate microperfuranone attached to the T domain (PubMed:22627757).  Finally, microperfuranone is released by the TE domain (PubMed:22627757).
What are the official names of this protein?
Microperfuranone synthase, Nonribosomal peptide synthase micA.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HLDE_NITOC
Sequence: MTHGLPHFTSAQVLVIGDVILDRYWHGTTSRISPEAPVPVVQVTGREDRPGGAGNVAVNVAALGAEVTLLGLIGADEAAAALRSLLAHRGVHCCLEGLPNIATLTKLRVISRHQQLIRLDFEDDFIPAHGEALLPAYSTALRGKSVVILSDYGKGTLQEPQRLIALGREVGVPILIDPKGADFSHYHGATIITPNLAEFEMVVGPCPDEASLVWKGEQLRQQLALKALLITRGEQGMTLLEQGHSPVHLPTEAREVFDVTGAGDTVISVLGAALAAGGTFKEATLLANQAAGIVVGKLGTASVTRDELQQALHPRAIRRGITSEEELLHFINLARSRGECIVMTNGCFDILHPGHVNYLAEARQLGDRLIVAVNDDASVQRLKGKNRPINSLAQRLTVLAALHDVDWVVPFSEDTPARLIERVLPDILVKGGDYTPEQIAGANAVVANGGKIIILTYQQGCSTSQIIDIIRKN
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RF1_CAUVC
Sequence: MRLPQARLDQVLDRFREVEARMGAATDGAEIVKLSKEHAELRPVAEAVERLAKLSAERAELDVMASDPEMAEMVRDEIQALDEKLPVMERELALMLAPKDKDENASAILEVRAGTGGDEAALFAGDLFRMYQRYAQTQGWRVEIDSISEGEMGGFKEIVASITGDGVFGRLKFESGVHRVQRVPATEAQGRIHTSAATVAVLPEAEDVEIEIKESDLRIDTYRSSGAGGQHVNKTDSAVRITHLPTGVVVTSSEKSQHQNRARAMKNLKARLYDMQREALDSARSEARKSQVGSGDRSERIRTYNFPQGRVTDHRINLTLYNLARIMEGDALDDVINPLIAEDQAERLASLEESFS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_MARSD
Sequence: MAEVKPVTAVFPGTFDPFTRGHFSLVMRGIKTFHKVIVAVAGSTSKNTKFSLEERVDMAKRIFEHHPQVEVDSFDGLLVHYVEQSPANVIMRGLRAVSDFEYEFQMALMNRRLDNDIQTVFLMTDYKWMYLSSSIIKDVAVNGGDIKGLVPRQIYDEVIERLVPGK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBOA7_BOVIN
Sequence: MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHVAQRKEMASGFSKGPPLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEMAASLEYDYETIRNIDCYNTDFCVTVREGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAERQLESALRWRLGPGGQKAWDWVHWFLKMRAYDYMSMGFVLLSLRDTLRYWASVYFCVHVLALAALGLGLALGRGGPGRRKSGAPAPSPASGKLREE
What is the function of this protein?
Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.  Prefers arachidonoyl-CoA as the acyl donor, thus contributing to the regulation of free levels arachidonic acid in cell.  In liver, participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation.
What are the official names of this protein?
Lysophospholipid acyltransferase 7, LPLAT 7, Leukocyte receptor cluster member 4, Membrane-bound O-acyltransferase domain-containing protein 7, O-acyltransferase domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localized in specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria.
Protein: RL10_XANOR
Sequence: MALNLSQKQEVVAELADVAAKAHSLIAAEYAGTTVSQMTAMRKQARETGVFLKVVKNTLAARAVEGTDFAVAADKLVGPLLYAFSMEEPGAAGRLIKEFAKSNDKLQAKVVSIGGELFPAGHVDVLASLPTRDQALAMLARVLSEPAAMFARAVKAVGDKQGGGDAAAAAVAETAEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RPOA_ORYSI
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGETEGTCITHAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRTASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPTDFRIELRIKRDRGYHTEVRKNTQDGSYPIDAVSMPVRNVNYSIFACGNGNAKYEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHTEEEGTRFQENKNRFTSPLLSFQKRLTNLKKNKKRIPLNCIFIDQLELPSRTYNCLKRANIHTLLDLLSKTEEDLMRIDSFRMQDGKQIWDTLEKHLPMDLPKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYB_PACSA
Sequence: MAPNIRKSHPLLKMVNNSLIDLPTPSNISSWWNFGSLLGICLMTQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYFHIGRGLYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTLIHLTFLHESGSNNPLGIVSNCDKIPFHPYFTLKDILGFTLMFLPLTTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLIPFLHKAKQRTMTFRPISQLLFWILVANLLILTWVGSQPVEHPFIIIGQLASVTYFTILLVLFPIIGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RIMO_PROM0
Sequence: MKQNSLNVKQKKLSKIAFSHVGCEKNLVDTEHMQGLLHKEGYEVDSNINDANVVVVNTCSFIETAREESIRKILEYTNQGKEVIVAGCMAQHFKDELIKEIPEIKGLVGTGDYQKIAKVLDRVEKGEIVNEVSKIPEFIADEEMPRFVDKNKFVAYLRIAEGCNYNCAFCIIPKLRGPQRSRTIESILSEAKSLAKKGIQEIILISQITTNYGQDIYGKPSLAKLLNELSKVPIPWIRIHYAYPTGLTDEVIRAFKDSKNIVPYFDLPLQHSHPDVLKSMNRPWQASLNESILEKIREEIPSAVLRTSLIVGFPGEKKEHFEHLLQFLDRHKFDHVGVFIFSPEEGTAAFHLPNKVSPEVAEARKDNVISVQQNISREKNQIYVGSKMKIMVEQISDNNELIGRSYNFAPEIDGTVILSVKEKIDLKNYIGKFVEANISFADEYDLYGETIKIL
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHAJ_ECO57
Sequence: MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFNGK
What is the function of this protein?
Positive regulator partially required for expression of genes in the locus of effacement (LEE) large pathogenicity island (PAI).  Also partially responsible for expression of neighboring gene dlsT (yhaO) during late exponential growth.  Binds to DNA of promoter 1 in LEE and DNA from the dlsT promoter region.
What are the official names of this protein?
HTH-type transcriptional regulator YhaJ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PHTF2_MOUSE
Sequence: MASRVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVVFFPFFSRWWLQVTSRVIFSWLLVLYLLQVAAIVLFCSAPSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLGTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQSYGAGAPYSVGTVFRDLWLAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKRTVKSSEDGAQYHELQCETVGPEDAAWATRTPRSVPAKDTQRKITNVSDEVSSEEGPETGYPLRGHVDRTSESGLRNRKPHHYKKHYANEDAPKSGTSCSSRCSSSRQDSESTRPESETEGVLWEDLLHCAECRSSCTSETDVGNPQINPCGKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNNHVPGIGYQVFGNAISLILGLTPFVFRLSQATDLEQLTAHSASELYVIAFGSNEDVMVLSMVLISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEIFLDCHCNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKLWKIKS
What are the official names of this protein?
Protein PHTF2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MATK_THUPL
Sequence: MDEFQRXSNKHXXWQQLFLXPLFFREDLXAIGHDHHLDRSGSSEPTEIFFSHFFSFLTVKRSIRRIRKQNKSISLFGNSDSNKLIEYNKNFSFKSMLEGFTIVLEVSIAMRSKHFIKGMDGWNXLRSIHCIFPFMEDKLPHSNYISDIRVPYSIHPEILVRIFRRWIRDVPSLHLLRLILHEWKNSFSQENLEKXXLITQRGNTRFSLFLWNSYVYECESFLIPLIKRFFNPXSLLYGSFPDGIHXEKKIKDIVIFLLQKISTKKIWLLKDSFIHYVRYGERSLIALKGTHLQVKKCRYHLFHFWQYYFHLWFQPYRICSLELSKTSFSFLGFFLNVKMRPLVVRAKMLDDLFITDLITNELNPIAPIRSILFSLAKEKFCDISGWPISKLSWTSLSDDDILDRFDRIWINLFHYYSGSINQDGLYHIKYILLLSCAKTLACKHKSTIRVVREQLGSELFTNSFSKEREFISSSFSKTRSQRERIWNSEISQRNPLXXFWQKMENKQIEN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PLB2_YEAST
Sequence: MQLRNILQASSLISGLSLAADSSSTTGDGYAPSIIPCPSDDTSLVRNASGLSTAETDWLKKRDAYTKEALHSFLSRATSNFSDTSLLSTLFSSNSSNVPKIGIACSGGGYRAMLGGAGMIAAMDNRTDGANEHGLGGLLQSSTYLSGLSGGNWLTGTLAWNNWTSVQEIVDHMSESDSIWNITKSIVNPGGSNLTYTIERWESIVQEVQAKSDAGFNISLSDLWARALSYNFFPSLPDAGSALTWSSLRDVDVFKNGEMPLPITVADGRYPGTTVINLNATLFEFTPFEMGSWDPSLNAFTDVKYLGTNVTNGKPVNKDQCVSGYDNAGFVIATSASLFNEFSLEASTSTYYKMINSFANKYVNNLSQDDDDIAIYAANPFKDTEFVDRNYTSSIVDADDLFLVDGGEDGQNLPLVPLIKKERDLDVVFALDISDNTDESWPSGVCMTNTYERQYSKQGKGMAFPYVPDVNTFLNLGLTNKPTFFGCDAKNLTDLEYIPPLVVYIPNTKHSFNGNQSTLKMNYNVTERLGMIRNGFEAATMGNFTDDSNFLGCIGCAIIRRKQESLNATLPPECTKCFADYCWNGTLSTSANPELSGNSTYQSGAIASAISEATDGIPITALLGSSTSGNTTSNSTTSTSSNVTSNSNSSSNTTLNSNSSSSSISSSTARSSSSTANKANAAAISYANTNTLMSLLGAITALFGLI
What is the function of this protein?
Sequentially removes both fatty acyl groups from diacylglycerophospholipids and therefore has both phospholipase A and lysophospholipase activities.  However, it does not display transacylase activity.  Substrate preference is phosphatidylserine > phosphatidylinositol > phosphatidylcholine > phosphatidylethanolamine (PubMed:10231538, PubMed:10497163).  The substrate specificity is pH- and ion-dependent.  In contrast with activities observed at optimum pH 3. 5, the order of substrate preference at pH 5. 5 is phosphatidylserine = phosphatidylethanolamine > phosphatidylcholine > phosphatidylinositol (PubMed:15588231).
What are the official names of this protein?
Lysophospholipase 2, Phospholipase B 2.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI- anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI- CWP).
Protein: ATPG_CAUVN
Sequence: MASLKEMRNRISSVKATQKITKAMQMVAAAKLRRSQDAAESARPYARRLASVIANLAAGVSGDGAPKLLAGTGRDDRHLVVVAAADRGLAGGFTSSIVRAARAHIDGLIAQGKDVRVVCVGKKVTAQLAKPYAGRIVETFDLSSYRQLTLSVAQPIADVITREYEAGETDVVTLFYSRFKSVVQQIPTGLQLIPAVVETGEAASGPTAVYEYEPSEEAILETLLPRNLTVQILSALLDNMAGFYASQMTAMDNATRNAGDMIKRYTLEYNRSRQAQITKELIEIISGAEAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GUAA_TRIV2
Sequence: MNTAVTLLTEQAPQPIEEFGQLERQIIIILDFGSQYSELIARRIRETQVYSEVLSYRTSAEHLRQLNPKGIILSGGPSSVYSDRAPHCDPEIWNLGVPILGVCYGMQLMVNQLGGEVAKADRGEYGKASLHIDDPTDLLTNVEDGTTMWMSHGDSVTKMPPGFEVLAHTDNTPCAAVADHDKKLYGVQFHPEVVHSIGGLALIRNFVYHICECEPTWTTAAFVEEAIREVRAKVGDKRVLLALSGGVDSSTLAFLMHKAIGDQLTCVFIDQGFMRKYEPERLVKLFQEQFHIPVEYVNARDRFLDIMVGVTDPEEKRRRIGHEFIQVFEETSRNLGPFDYLAQGTLYPDVIESADTNVDPQTGERVAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVRKVGRSVGLPEEIVQRQPFPGPGLAIRILGEVTADRLNILRDADLIVRQEINQRGLYNEYWQAFAVLLPIRSVGVMGDQRTYAYPIVLRIVKSEDGMTADWARVPYDVLEAISNRIVNEVKGVNRVVFDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PRSX_ECOLX
Sequence: MNNTDTLEKIIRHQKNKDPAYPFQEHLLMQLCIRANKRMQDNISEFLGAYGINHSVYMVLTTLFTAESHCLSPSEISQKLQFTRTNITRITDFLEKTGYVKRTDSREDRRAKKISLTSEGMFFIQRLTLAQSMYLKEIWGYLTHDEQELFEVINKKLLAHLDDVSS
What are the official names of this protein?
HTH-type transcriptional regulator PrsX.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_METFV
Sequence: MIISPEEERSLIIKILNALGVSEEHAKITADVIVDADLKGFTSHGIGRFPQYVEGIKLGTIKTSGNIEIEKETDSVALINGNHLLGQVVAYKGMKLAIEKAKNTGVGIVGIHDSNHFGIAGYYSDMAMKNDMIGITMTNTEPAVAPLGGKIPVLGTNPIAISIPSNEYYVAVDMSTAAVARGKLLEAARKNEKIPEGIAVDKNGNPTTDPNEALNGSILPFGGHKGYALCFMIEILAGPLVKAEFGSKVKGTVDPSQMCTKGDLLIAIDPSKFYDIEEFKRNVDEFVKEIKSTGKDVLIPGDRERMNIKKREKEGIELDKKLVEKLKEIADELNIELTW
What is the function of this protein?
Acts on oxaloacetate, sulfopyruvate but not on pyruvate.  Has a higher selectivity for the coenzyme NADH than for NADPH.
What are the official names of this protein?
Malate/(S)-sulfolactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_ECOSM
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: HIS6_PROM1
Sequence: MVALRLIPCLDVSNGRVVKGVNFVGLRDAGDPVELGCRYSKAGADELVFLDITATHEKRSTLVDMVRRTSEAVTIPFTVGGGISSLNGINELLRAGADKVSLNSSAVKDPSLISQGANRFGSQCIVVAIDAKKNKHIPNKWDVYVSGGRKNTGLDAIEWAEKIFEMGAGEILLTSMDGDGTQNGYDIELTRCISEKVSIPVIASGGAGSLSHIKDAFTLGKSSAALLASLLHDGQLTIREIKEYLIKENLPIRPIE
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_NCBVS
Sequence: MEDASKQLRVLDAQERAKAAFQLDFIASVETLEDAQEKYEGMMFRSGTKLPSTHIKLAIDLRVAEKDLRRHVKNVPTVLEIGPSVESVRYAVQTRDKERVHGCTFSDARDNLRHNKIGYEAHYDRKIGPDAALLAAGIPTDTFCVDGFSNCEYQSPLAIACHSLYPDGESNSIMDVAKGMALHGTHVIYAWMHLPVELLTLTDADNIFEGYSIRFEETGALPCTKRRKAIFSGYNDFGSAYVHDAHHWAGWLKHRGVDTPYGFSILIDIQQRFGMHTKLKITRGHSSGSITTVFPLSKLGLIWVPNIVKIMYPKAKHEPEYIVTDKKKYEGVCVYVGTRVQSSGKSITLAEIVQYIRTRLTRIILNGTVHEKTWTIAEQDIERLAVSIMFRKNVERAVSEKALMRAQKKCKSAEKQALLPVWMRRIANWFQDKFQIDEEVVRKRYLECLKAQPWIHADKVVNCETKRYNPTVAEVGPKNHLLATTGLRELQREIPSANEPQDRGAKAWHSAHADLDIYAEGLRLDSAKEAAAGKQSLAITLQQAFQVLGKTKCEGCNNIEIEYWTGPPGSGKSRAAKPRFADLQGGVLYCAPTRTLRDALDESVVHPSRVCTYHNALHVAAKESGNRPFDVIVIDEAETTPACYVGTMHHASPSSRIVCLGDPHQIGYIDFSDRKDDLKPFSIIAAECRTRRFNTTYRCPQDVLNLPIFKTLYPDAISFSKQLTSIRYLTRARSVTRTRHAQTLTQDQKPHSEPPVTAHEPQARRTDVIVHYAGTLPERALLEKVRHINVALTRHTNALYIRDESEKGELVPSLMTPPSWSTYRCTPVDKQMVPDPVAVERENGSSGPCDSHHIGAITILQELGKLTDTKGVRVFESEAVPTAHRRVVLDGNLDSGPDRYPMYQFTNLRGTKYTNIKDNQQALHTLVGRYARKINSSSREDAEFDVKRITARLKEWIPFRTAEPEQVDSCFADAMQKIAERGHGVDDIEDFWSNEGQRISYHLKGQQKVMDPTKLKLGQGISAHEKCANIALSAWVRIIQDQMSTSEKFIFANGQSDRDTMSIIEARLQEKAREFKSIDIKEFDTVHNWVSILVFSWRCDRGCPEHLIEYFEKRSKSRTLSSRIGSVDVSFMLDSGAVWTIARNTLFASGLMLALFVGVDFIAAKGDDVFLAGNNLYLDAERLRMGSYLAANNLKIEKTAVVSFIGFIVSQAAVTADVVRLATRTYGRSYKNADDLAKYKIAIADHCKLFRSPRTRLMTAINCATLYGTSKECINYLMDALDAFGHTKMSDLHLDPGFVMRVTPMKVDERVYSGQDGCQRADKTREKQPEPGQPGPQQQQQASTQEAGSKTSPRSRTDYQPRPDGRTREPREHPGQPRSDTREGVKASDDGESHGSDIRGMDSRLSRPGRRIQDEPGRRENSRRRDTSVNMRSISRDRGRQIPGTEFYDATAGWRDLASTSDASPVLQASVVVHHHHQQHGSRSDERRSGCVRERLEQQDGLDRSDVPKLGASRERVLHGRPDRSADGRTTPDSTGCIRVTRELPSDIERRHSVLQRTHSRESGSGGDRAVPTGQRTPEGEPGHSSRDHPNGRNVTARRFRAELHIDDDDRGPGRVRGRSNPATHGVDGADAGVGAAGVPDCEPDIRRRKHNHHHDHAATRVGDGNVAIHSQQRDGHRDRGRGSATVRVRSEFGRLGTESAGHQLNQDSTNEHEPNDAGNAQDHSVPTQRNEGLLYAPEGVPTRVRNDNGDVLWTGAMEDTEDNCGRLPPGNWWTPGYHRQQLRDRRCRDDRYVYINRTLLQGVPTLRSDTGGGEPLGPLRQCDTSEGRRGANSGSNLDRSAPIRIPGTIQRIRGPIRDGGQDHSPDTSLCAISSRSGECGDGLHRERDRECSLEFHLGEAATKSETCWRNRSRSPQSCGPHREP
What is the function of this protein?
RNA-dependent RNA polymerase replicates the viral genome.
What are the official names of this protein?
Methyltransferase/helicase/RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.