PharMolix/UniProtQA huggingface dataset:
Protein: AMPA_RICFE
Sequence: MLNINFVNEESSTNQGLVVFIDEQLKLDSNLIGLDQQHHGLISKTIQNKLQFTGKYGQIKVIPSVIKSGEVRYLIIAGLGNEEKLTEAKIEELGGKILQHAICAKISTICLKLTNRISRFTSQTFASLVASGAFLASYRFNKYRTTLKEAEKFAVESIEIFTDNSTEAAKLFEVKKLIAEAVFFTRDICNEPSNIKTPQVYAERIVDILEPFGVDVDVIGEREMKNLGMGALLGVGQGSQNESKLVVMEYKGGNKDVPTIALVGKGVIFDTGGISLKPSSNMHLMRYDMGGSAAVVGAMIAVAGQKLPVNIVGVVGLVENMPSGNAQRPGDVVTTMSGQTAEVLNTDAEGRLVLADAVWYAQEKFKPKCVIDVATLTGAITVALGSTYAGCFSNNDELADKLIKVGEEVNEKLWRMPLHDEYDAMINSDIADMANIGNVPGAAGSCTAAHFIKRFIKDGVDWAHLDIAGVANSNKASALGPKGAVGYGVRLLEKFIKEYI
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYP2_AMYS7
Sequence: MPVDLSTTLSWKSATGEAATMLDELQPNILKAHVRDRLTVLFLGFGDAAEARTFLNGLSGLMKSARTHLQEVEAHKLTKAVGTPYLGVGLTAHGYATLGVTAPADPSFTAGAKAAVEKLADPAVTEWEGHYQQTIDAVLLLGDATAGPVRTLRRQVEALRPASVTVVGEESGLGLANANGDGIEHFGYVDGRSQPLFLTEDVDAERDTTDGVNDWDPSAPLEQVLVPDPAAPDPTVHFGSYFVFRKLEQNVRLFKEAERDLAHDLGLRGEDRERAGAMLVGRFEDGTPLTAQSAPGSHHPVGNDFSYDSDKLGQKCPFHAHIRKTNPRGSGGAEAPEEERKHLMARRGQTYGRRHDDPNADLPPRLRPAKDVGLLFMAFNSNLGNQFEFTQQIWANNPAFPFPPDGSQPGLDPVIGQGARAPQKYAPEWGHNNVAEATDPIPQAVTMKGGEYFFMPSLAFLRSL
What is the function of this protein?
Displays both high peroxidase and manganese peroxidase activity.  Is likely involved in lignin degradation.  Also has a Mn-dependent oxidase mode of action that expands its substrate scope in vitro; is thus able to catalyze the O(2)- and Mn-dependent oxidative decarboxylation of 4-methoxymandelate to anisaldehyde.
What are the official names of this protein?
Multifunctional dye peroxidase DyP2, Dye decolorizing peroxidase 2, DyP2, Manganese peroxidase.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family.
What are the subcellular locations of this protein?
Secreted. Note=Although no signal sequence is found, the secretory machinery for actinomycetes is not fully characterized, and the low pH optimum for DyP2 along with the observation that many DyPs have been isolated from the secreted protein fraction imply that DyP2 could be secreted and still possibly play a role in extracellular oxidation chemistry (PubMed:23054399).
Protein: DCUP_FRAP2
Sequence: MRKLFLDAFKHEKLEKPPIWIMRQAGRYLPEYRAVRSKFENFMDMCRNADACCEVALHPLERYDLDAAIVFSDILTIPEAMGMDLKFIKGVGPVFSDPIESEKDLNRLKSAEDSVGDLEYVYNAVRTTKAAINVPLIGFTGSPWTLAAYMVEGSGSKQFSKLRKMMYANPQLMHALLQRLADITVIYLLEQVKAGASSLMIFDTWGGILPLEQYKEFSLKYMEYIAKNVKQKSNVPVVFFTKGGSNFFEELKDKSCDGVGVDWNVTLDQARHRIGVGKVLQGNFDPAFLYGTSDSIRNTVKKNMEFIQSDKLNNYIVNLGHGIYPDINPDNVKIMVDAIREFSV
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPT32_YEAST
Sequence: MSNEDYGYDYDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLTELRENADDNVAVGLIGNKSDLAHLRAVPTDEAKNFAMENQMLFTETSALNSDNVDKAFRELIVAIFQMVSKHQVDLSGSGTNNMGSNGAPKGPTISLTPAPKEDKKKKSSNCC
What is the function of this protein?
Required for protein transport through the secretory pathway.  Probably involved in regulation of secretory vesicle formation at the trans-Golgi compartment.  Mediates the proper polarized localization of SEC2, a GEF for SEC4, but does not alter the exchange activity of SEC2 on SEC4.  Plays a role in autophagy.
What are the official names of this protein?
GTP-binding protein YPT32/YPT11, Rab GTPase YPT32.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid-anchor.
Protein: RL5_PARD8
Sequence: MSNTASLKKEYQDRIVPALTKEFGYKSVMQVPVLKKIVINQGLGMATADKKIIDIAISELSTITGQKAVATVSKKDISNFKLRKKMPIGVMVTLRREQMYEFLERLVRVALPRIRDFKGIESKLDGRGNYTLGIQEQIIFPEINIDNITKILGMNITFVTSAKTDEEGYALLREFGLPFKNGKKD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y121_ENCCU
Sequence: MESDVCRLLDEIQRDIDEEHLVFARRDFECKLEHHKAIRPLLLRRDSVISEALLEMYWGRALAGFDAARGILPRDGCDRTSTQWMRSLVAEYLDGYGYRVHIELNENEFVSNRTLTKRVDLSLASVEKTGVVWRGNRRYPVFEFFESDTQDLDMFDILYELYVNSASYFLMSSRSHPMP
What are the official names of this protein?
Uncharacterized protein ECU01_0210/ECU01_1400.
Protein: RSMB_DROME
Sequence: MTIGKNNKMIQHLNYRVRIVLQDSRTFIGTFKAFDKHMNLILGDCEEFRKIRSKNSKVPEREEKRVLGFVLLRGENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMPINLSAVPAGLQGPVRGVGGPAQQHMAPMGRGVPRAPMMGAPPPGMIPGGMPSMPGNMGRGAPPPMRGPPPSMIRGAPPPGRGGY
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).  Involved in germline establishment and development (PubMed:20570937, PubMed:20659974).
What are the official names of this protein?
Small nuclear ribonucleoprotein-associated protein B, snRNP-B, Sm protein B, Sm-B, SmB.
What is the protein family that this protein belongs to?
Belongs to the snRNP SmB/SmN family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, Cajal body. Cytoplasm, cytosol.
Protein: RSGA_PEDPA
Sequence: MHTGQIIQLLAGFYDVLTEDHKIVRTRARGNFRNQKTSPLVGDMVDFKESENDTGYITKIHTRENELVRPPLANIDQAVIVTAATEPSFSANLLDRQLVALAEKHIEAILYFSKTDLLSPTEFQDLQKIAGYYQKIGYQVIFPISSQPDADLIELKESFKNQLTIFMGQTGAGKSTLLNRIDSKLNIATGEVSQALNRGKHTTRKVSLIPIEDGLVADTPGFSTYAVFEMADTQLKEYFIDFKKLSQNCRFRECLHLNEPGCAVKAAVEDGSVLSSRYANYEQFIELIRNQKPEYKRKGYQKKDRRKKK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_HALH5
Sequence: MSNLPNELKYSEEHEWVKVEGDKVRIGITDFAQSELGDIVFVELPEVGDEVEADEPFGSVESVKTVSELYAPVSGKVVEVNEELDDNPEYVNESPYEKAWMIVVEPSDASQVEELMSADEYKEMISEE
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: TAAR6_PANTR
Sequence: MSSNSSLLVAVQLCYPNVNGSCVETLYSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLIDCLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPAYIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood (By similarity).
What are the official names of this protein?
Trace amine-associated receptor 6, TaR-6, Trace amine receptor 6, Trace amine receptor 4, TaR-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIBBA_THEMA
Sequence: MEELREAFEEGKPVILIDRNRENEADFVFPAQLITEDVVSFFVTYGKGLFCVTADEEDLLKRGFVKLSSNYGANYFVPVDWGTGTGISALERAETCRKLAEGRYFHEFRYPGHVTVIGGIGFQRRKGHTEASLEISELAGFSRHAVIVEILDEKGNSHNLDYVLKLSEKFSLPVLEMDDVWREFVKRKLLMKKKAEATLPTDFGVFKVVSFENHLDGKEHFAIVKEPLEDPVAVRIHSECVTGDVLSSLRCDCGSQLANFLRYMSAHGGILIYLRQEGRGIGLSNKIAAYSLQDKGLDTVEANRVLGFSEDERDYAPAAQILKALGIERVLLFTNNQRKTVGLEKYGIEVVETKRLYGRVTPHNRFYLSTKMKKLGHELEEIFREVNS
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: PAGL2_LACP3
Sequence: MNQNKQFSIVIAGGGSTYTAGIVMMLLENAERFPLRALKLYDIDEERQATIAEAIAIELKEKAPAIDFTWTTDPQTAFTDVDFCFAHIRSGGYKMREQDEKIPLKHHVVGQETCGPGGIAYGMRSIGDIIELIDFIEKYSPDCWMLNYSNPASIVAEACRRLRPDAKILNICDMPVGTQRRMSQIIGLQPKDLEVRYFGMNHFGWWTSVKDKAGNEYLPQIRDYVAHHGYLTQIEVDTQHMDASWQATHKKAQDLLAVDPHYLPNTYLKYYLYPDYVVAHSDPDYTRANEVEDGREKCVFSAAQKIIDAGTSDVGSFPIDSHASFIVDLACAIAFNTHERMLLIVENNGAVANIDDNIMVEVPCIVGKDGAEPLTQGKIPMFQRGMILNQAMVEKLVVDAWINHDYQELWQALTLSKTLPSAQVAKEVLDDLIEANREYWPELKHDEHEVHLISESAVSEI
What are the official names of this protein?
6-phospho-alpha-glucosidase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
Protein: SUVHA_ARATH
Sequence: MGLVGLHSGTIDMEFIGVEDHGDEEGKQIAVSVISSGKNADKTEDPDSLIFTGFGGTDMYHGQPCNQKLERLNIPLEAAFRKKSIVRVVRCMKDEKRTNGNIYIYDGTYMITNRWEEEGQNGFIVFKFKLVREPDQKPAFGIWKSIQNWRNGLSIRPGLILEDLSNGAENLKVCLVNEVDKENGPALFRYVTSLIHEVINNIPSMVDRCACGRRSCGSKHVFREKLSVSSSLVISAKKSGNVARFMNHSCSPNVFWQSIAREQNGLWCLYIGFFAMKHIPPLTELRYDYGKSRGGGKKMCLCRTKKCCGSFG
What is the function of this protein?
Histone methyltransferase family member that may lack methyltransferase activity.  May methylate 'Lys-9' of histone H3.  H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression (Potential).
What are the official names of this protein?
Putative inactive histone-lysine N-methyltransferase family member SUVH10, Histone H3-K9 methyltransferase 10, H3-K9-HMTase 10, Protein SET DOMAIN GROUP 11, Suppressor of variegation 3-9 homolog protein 10, Su(var)3-9 homolog protein 10.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associates with centromeric constitutive heterochromatin.
Protein: TSAD_STRPJ
Sequence: MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAATYGPGLVGALLVGLSAAKAFAWAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETRDDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANKGLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDTME
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_BACAH
Sequence: MTAIRYEFIKTCKQTGARLGRVHTPHGSFDTPTFMPVGTLATVKTMSPEELKAMDSGIILSNTYHLWLRPGHEIIREAGGLHKFMNWDRAILTDSGGFQVFSLSDFRRIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPFPATFEYMKKSVERTSRWAERCLKAHERPQDQGLFGIVQGGEFEELRRQSAKDLVSMDFPGYAVGGLSVGEPKDIMNRVLEFTTPLLPDNKPRYLMGVGSPDSLIDGAIRGIDMFDCVLPTRIARNGTCMTSEGRLVVKNAKFARDFGPLDPNCDCYTCKNYSRAYIRHLMKCDETFGIRLTSYHNLHFLLNLMEQVRQAIREDRLGDFREEFFEQYGFNKPNAKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PG200_VARV
Sequence: MTANFSTHVFSPQHCGCDRLTSIDDVRQCLTEYIYWSSYAYRNRQCAGQLYSTLLSFRDDAESVFIDVRELVKNMPWDDVKDCVEIIRCYIPDEQKTIREISAIIGLCAYAATYWGGEDHPTSNSLNALFVMLKMLNYVDYNIIFRRMN
What is the function of this protein?
Contributes to virulence by binding to the host IKBKB subunit of the IKK complex and preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B.  Mechanistically, sterically hinders the direct contact between the kinase domains of IKBKB in the IKK complex containing IKBKB, CHUK/IKKA and NEMO.
What are the official names of this protein?
Protein OPG200.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG200 family.
Protein: PAPS3_ARATH
Sequence: MKKGGGRNKGFPQDDESSISLRQLMVNEGLIPSLEDEVKRRGVINQLRKIVVRWVKNVAWQHRLPQNQIDATNATILPYGSYGLGVYGSESDIDALCIGPFFASIAEDFFISLRDMLKSRREVSELHCVKDAKVPLIRFKFDGILVDLPYAQLRVLSIPNNVDVLNPFFLRDIDETSWKILSGVRANKCILQLVPSLELFQSLLRCVKLWAKRRGVYGNLNGFLGGVHMAILAAFVCGYQPNATLSSLLANFFYTFAHWQWPTPVVLLEDTYPSTGAPPGLMPIQLPCGSHQYCNSTITRSTFYKIVAEFLLGHNLTKDYLKLNFSWKDLFELYPYANTYTWFTKIHLSAANQEDLSDWVGWVKSRFRCLLIKIEEVYGICDPNPTEYVETYTKQPNIVFYWGLQLRTINVSDIESVKIDFLKNVNSGSFRGTVGRIQLTLVKASQLPKNGECGSNNRSKKVTKTCWRIREDKQCNNVPVYSKHLPGYVVGYQKMVNREADGMEVKC
What is the function of this protein?
Essential protein (PubMed:19956626).  Polymerase that creates the 3'-poly(A) tail of mRNA's (PubMed:15297145).  Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites.  May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity).
What are the official names of this protein?
Nuclear poly(A) polymerase 3, PAP(III), Poly(A) polymerase III, Polynucleotide adenylyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the poly(A) polymerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATF6B_HUMAN
Sequence: MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFRCPEQDVPFDGSSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSEALGVGEVLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSVNSEASLLSADSSSQAFIGEEVLEVKTESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTRKPPLQPKPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLPRPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAVLADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCIMVFLLFIAFNFGPVSISEPPSAPISPRMNKGEPQPRRHLLGFSEQEPVQGVEPLQGSSQGPKEPQPSPTDQPSFSNLTAFPGGAKELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKIPQRAQERQKSQPRKKSPPVKAVPIQPPGPPERDSVGQLQLYRHPDRSQPAFLDAIDRREDTFYVVSFRRDHLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGAPGDYEEMMQIECEVMDTRVIHIKTSTVPPSLRKQPSPTPGNATGGPLPVSAASQAHQASHQPLYLNHP
What is the function of this protein?
Transcription factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress (PubMed:11256944).  Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE (PubMed:11256944).
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein, Creb-rp, cAMP-responsive element-binding protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Processed cyclic AMP-dependent transcription factor ATF-6 beta]: Nucleus. Note=Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Protein: ERA_STRP4
Sequence: MTFKSGFVAILGRPNVGKSTFLNHVMGQXIAIMXDKAXTTRNKIMGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGDDMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSRLVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMKRDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWVKVKKNWRDKKLDLADFGYNEREY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: O1009_MOUSE
Sequence: MADENYTRITEFIFIGLRYHPNLQVFLFLLFLLFYLVTMTGNLGMIILIRVDSRLHTPMYFFLSHLSFVDICFSSVVAPKMLTDFFADKKAISFLGCVLQQWFFGFFVAIECLLLASMAYDRYVAICNPLLYSVAMSQRLCIQLVIGPYAVGFFNTMTHTTAAFRLPFCGSNIINHFFCDMSPILSLICADIRINKLLVFIVAGAVLIVSSTTIIVSYFHILIAILRIRSAEGRRKAFSTCSSHVTAVSILYGTLFFIYVRPSAISSLDLNKVVSVFYTAVIPMLNPLIYSLRNKEVKSAMGRTVAKAKVFLKN
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 1009, Olfactory receptor 175-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TOM5_MOUSE
Sequence: MFRIEGLAPKLDPEEMKRKMREDVVSSIRNFLIYVALLRVTPYILKKLDSI
What are the official names of this protein?
Mitochondrial import receptor subunit TOM5 homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom5 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: DLTA_STRPN
Sequence: MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDSLAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEVAEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTTGKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGTLFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDGEELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADSPTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGTMTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLLAYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKGLINEVNKR
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD25_XENTR
Sequence: MVFYFTSNVISPPYTMYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLQKDQTIEDIPKEVLLDCAQLVKANSIQGCKMNNINVVYTPWANLKKTADMDIGQIGFHRQKDVKTMTVEKVSKIVNRLEKTKDERFPDLAAEKEARDREERNEKKAQIQEIKRKEKEEMKKKKEMDELRSYSSLMKSENMSSNQDGNDSDDFM
What is the function of this protein?
Transmembrane receptor that senses neutrophil extracellular traps (NETs) and triggers the ILK-PARVB pathway to enhance cell motility.  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation.  Specifically binds NETs on its extracellular region, in particular the 8-OHdG-enriched DNA present in NETs, and recruits ILK, initiating the ILK-PARVB cascade to induce cytoskeleton rearrangement and directional migration of cells.
What are the official names of this protein?
Coiled-coil domain-containing protein 25.
What is the protein family that this protein belongs to?
Belongs to the CCDC25 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endomembrane system. Note=Localizes to cytoplasmic membrane in tumor cells.
Protein: RL18_CLOK5
Sequence: MFKKYDKKKLRKKRHLRVRKKIFGTSEVPRLSVYRSEKNIYAQIIDDIKGTTLVSASSVDKDFKGNGSNKEAAKVVGKMIADKAIEKGIKEVVFDRGGYIYHGRVQNLAEGAREGGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SYH_SULDN
Sequence: MISSLRGMNDILSEDYERFTHFITVATKIAQRYGFHFIETPLLEETALFKRSVGESSDIVGKEMYQFVDKGENDVCLRPEGTAGVVRAFVQKKLDRAGGIHRFFYHGAMFRYERPQKGRLRQFHQFGVESFGESSVYEDASMIMMASDILKELGIGYRLQLNSLGCNECMPPYREKLINFVTKHKDEICEDCTRRVETNPIRVLDCKNEKCQSIYTEAPKLLNCLCSTCESDFTTLKMILKQNEIDFEIDTNLVRGLDYYSKTAFEFVSDNIGSQSAIAGGGRYDRLVEFLDGRPTPAVGFAMGIERLMELIIMPEAKKDGYYLGAMDDEALDMIVKIAQKKRKSDIVILEYKTKNLKNHLKAADKSNAKYCAVIGSNEIKDGTIWVKNLEDKTEKTILSELF
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.