PharMolix/UniProtQA huggingface dataset:
Protein: SGCQ_ECOLI
Sequence: MSWLKEVIGTEKAVIAMCHLRALPGDPSFDAQLGMNWVIDKAWDDLMALQNGGVDAVMFSNEFSLPYLTKVRPETTAAMARIIGQLMSDIRIPFGVNVLWDPVASFDLAMATGAKFIREIFTGAYASDFGVWDTNVGETIRHQHRIGAGEVKTLFNIVPEAAVYLGNRDICSIAKSTVFNNHPDALCVSGLTAGTRTDSALLKRVKETVPDTVVLANTGVCLENVEEQLSIADGCVTATTFKKDGVFANFVDQARVSQFMEKVHHIRR
What are the official names of this protein?
Putative sgc region protein SgcQ.
What is the protein family that this protein belongs to?
Belongs to the BtpA family.
Protein: RL18_EHRRW
Sequence: MLATSNRFERRKRRVRLKLKNNLSLLRLSIFKSNRHFYVQLIDDSCGKTYAAASTLEREVIALAHRRVNSNSVKIVAKLMSERLNKLDNCKKFVFDRGPYKYIGVVAEFANELRSYGFEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL14_BURA4
Sequence: MIQTESRLEVADNTGAREVMCIKVLGGSKRRYAGIGDIIKVTVKEATPRGRVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLNNKLEPIGTRIFGPVTRELRSERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: LPTD_PHOLL
Sequence: MKKCYPTLLATTVWAALYGQYAHADLAAQCMLGIPVYDQPIINGDLNQLPINILADDSRADYPRSAKFIGNVNIKQGNKTLTADQVQLDQTEDKVPLRTVTATGNVHYDDPLIILKGPRAWSNLNNKDTDMYQSDYQMVGRQGRGTADKMKLRGENRYAILDNGTFTSCLPGNDSWSVVGSEVILDREEEVAEIWNARFRVANVPIFYSPYLQLPIGNKRRSGFLIPNASYSKNDGFEFLLPYYWNIAPNYDATITPHYISKRGLKLDNEFRYLTKAGTGTLALDWLNNDEQYVKDKKTNTRTARESDNRWLFYWRHSGVMDRVWRFNIDYTKVSDPEYFSDFSSQYGSTTDGYATQKFSLGYAQQNWNATLSTKQFQIFSKDTSRKAYRAEPQLDLNYYKNDLGPFDLKVYGQAAKFTSVGKNNPEATRWHLEPSINLPLSNGWASMNNEVKLMATHYQQDIPKATENAEYKESVNRVLPQFKSEAKMVFERSTYLNNNYTQTLEPQVQYLYVPYKDQDNINNFDSSLLQTDYNGLFRDRFYGGLDRISSANQVTTGLTTRIYDESLVERFNLSLGQIYYFERPRTGKETIINSKDSTGMMTWAGDTYWKINDSWGLKGGMQYDTRLGNVTMGNAVLEYRRDEDRLVQLNYRFVDRDYIQATAKSAPAFQQGISQVGLVASWPLSERWGLVGAYYYDTKEQQPASQLVGLQYNTCCWAINVGYERKIVGWKDNNSEYDNKWSFNFELRGLSNNHSLGSRKMLQSGIMPYQRAF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ORC3_YEAST
Sequence: MSDLNQSKKMNVSEFADAQRSHYTVYPSLPQSNKNDKHIPFVKLLSGKESEVNVEKRWELYHQLHSHFHDQVDHIIDNIEADLKAEISDLLYSETTQKRRCFNTIFLLGSDSTTKIELKDESSRYNVLIELTPKESPNVRMMLRRSMYKLYSAADAEEHPTIKYEDINDEDGDFTEQNNDVSYDLSLVENFKRLFGKDLAMVFNFKDVDSINFNTLDNFIILLKSAFKYDHVKISLIFNINTNLSNIEKNLRQSTIRLLKRNYHKLDVSSNKGFKYGNQIFQSFLDTVDGKLNLSDRFVEFILSKMANNTNHNLQLLTKMLDYSLMSYFFQNAFSVFIDPVNVDFLNDDYLKILSRCPTFMFFVEGLIKQHAPADEILSLLTNKNRGLEEFFVEFLVRENPINGHAKFVARFLEEELNITNFNLIELYHNLLIGKLDSYLDRWSACKEYKDRLHFEPIDTIFQELFTLDNRSGLLTQSIFPSYKSNIEDNLLSWEQVLPSLDKENYDTLSGDLDKIMAPVLGQLFKLYREANMTINIYDFYIAFRETLPKEEILNFIRKDPSNTKLLELAETPDAFDKVALILFMQAIFAFENMGLIKFQSTKSYDLVEKCVWRGI
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  It has a role in both chromosomal replication and mating type transcriptional silencing.  Binds to the ARS consensus sequence (ACS) of origins of replication.
What are the official names of this protein?
Origin recognition complex subunit 3, Origin recognition complex 62 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the ORC3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRAF2_MACFA
Sequence: MSEVRLPPLRALDDFVLGSARLAAPDPCDPQRWCHRVINNLLYYQTNYLLCFGIGLALAGYVRPLHTLLSALVVAVALGMLVWAAETRAAVRRCRRSHPAACLAAVLAVGLLVLWVVGGACTFLLSIAGPVLLILVHASLRLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS
What is the function of this protein?
May be involved in ER/Golgi transport and vesicular traffic.  Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis (By similarity).
What are the official names of this protein?
PRA1 family protein 2.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: HOA_MYCBT
Sequence: MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH
What is the function of this protein?
Involved in cholesterol degradation.  Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxohexanoate (HOHA) to pyruvate and propanal.  Can also catalyze the cleavage of 4-hydroxy-2-oxopentanoate (HOPA) to pyruvate and acetaldehyde.  The aldehydes produced by this reaction are directly channeled to the dehydrogenase HsaG.
What are the official names of this protein?
4-hydroxy-2-oxohexanoate aldolase, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase, 4-hydroxy-2-oxovalerate aldolase, HOA.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: RM22_XENTR
Sequence: MAASITASVWGTLLKIHRGLTASGCLPQSCVHTSAVLERSRHWEMKNRIVYPPQLPDEPRRPAEVYHCRKQIKYSKDKMWYLAKLIRGMSVDQAIAQLEFNDKKGAKIMKEVLLEAQDLAVRNHNVEFKSNLYVAESFSNKGKYLKRIRYHGRGMFGIMDKVYCHYFVKLVEGPPSPKEEPMTGFQQAKEYVQQLRSRTITHGL
What are the official names of this protein?
39S ribosomal protein L22, mitochondrial, L22mt, MRP-L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS5_BACLD
Sequence: MNMRRIDPSKLELEERLVTVNRVAKVVKGGRRFRFAALVVVGDKNGHVGFGTGKAQEVPEAIRKAVEDAKKNLIEVPMVGTTIPHEIIGRFGAGNILLKPASEGTGVIAGGPVRAVLELAGVSDILSKSLGSNTPINMIRATVQGLSELKRAEDVAKLRGKSVEELLG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PNP_STAA3
Sequence: MSQEKKVFKTEWAGRSLTIETGQLAKQANGAVLVRYGDTVVLSTATASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDDATLTARLIDRPIRPLFPKGYKHDVQIMNMVLSADPDCSPQMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGKYIINPTVEEKEVSRLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQRLVDFQQQIVDHIQPVKQEFIPAERDEALVERVKSLTEEKGLKETVLTFDKQQRDENLDNLKEEIVNEFIDEEDPENELLIKEVYAILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSEVGILPRTHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALKYIIPDTADFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITAIQMDIKIDGLTREIIEEALEQARRGRLEIMNHMLQTIDQPRTELSAYAPKVVTMTIKPDKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQAMINRAREIIEEITREAEVGQTYQATVKRIEKYGAFVGLFPGKDALLHISQISKNRIEKVEDVLKIGDTIEVKITEIDKQGRVNASHRALEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEGS_CANAL
Sequence: MDAEIKHRNSDKTFKFVTPPADSSIEVLNDFYWTDTDEPHVARRKMILQKYPEVTKLTGHEPKTKWYVMGVVLLQLGIAYYLRHTPVFSWKFLTLAYVIGATANQAIFLAIHELSHNLLFRKPLHNKLFAVFANIPIGVPYSASFQPYHQLHHKFLGDMYLDTDLPTEYEGRFLSSMPGKLFFAIFQIFFYALRPMFITQIKFTYVHLVNVVFQLIFDHVMVTCWGWKALGYFIVSTFLAGSLHPCAGHFIAEHYVLNENNVPRHQKIGGTNISKELLPAETYSYYGTLNMLTWNVGYHNEHHDFPYIAWTRLPELRRIAAEFYDPLPQVTSWCGVIWWFIFNDVNTVWNRVKREGKEKHGYRINRLDEN
What is the function of this protein?
Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.  Required for the formation of the monounsaturated sphingoid base (E)-sphing-4-enine during glucosylceramide (GluCer) biosynthesis.
What are the official names of this protein?
Sphingolipid delta(4)-desaturase, Delta 4-(E)-sphingolipid desaturase, Dihydroceramide desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LCB1_ROBPS
Sequence: MTSYNFKTQTSFPLLLSISFFFLLLLNKVNSTGSLSFSFPKFAPNQPYLIFQRDALVTSTGVLQLTNVVNGVPSGKSLGRALYAAPFQIWDSTTGNVASFVTSFSFIIQAPNPTTTADGLAFFLAPVDTQPLDVGGMLGIFKDGYFNKSNQIVAVEFDTFSNIHFDPKGRHMGINVNSIVSIKTVPWNWTNGEVANVFISYEASTKSLTASLVYPSLETSFIVHAIVDVKDVLPEWVRFGFSATTGIDKGYVQTNDVLSWSFESNLPGGNSVASVKNAGLSTYAA
What is the function of this protein?
N-acetyl-D-galactosamine specific lectin.  Bark lectins are storage protein that probably maintains stocks of nitrogen during dormant period.  Self-aggregatable molecules that can bind their own carbohydrate side chains.  They could also play a role in the plant's defense against phytophagous invertebrates or herbivorous higher animals.
What are the official names of this protein?
Bark agglutinin I polypeptide A, LECRPA1, RPbAI.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: TRHO_SHESA
Sequence: MSNVVVCALYKFVSLPHFESLREPLLSMMEQADIKGTLLLANEGINGTVAGSQAAIDALLAWLNNQNGLENIVYKLSFDDEMPFYRTKVKLKKEIVTMGVEGIDPLKVVGTYVKPQDWNALISDPEVILVDTRNDYEVQIGTFKNAINPVTETFREFPEYVKQNLDPAKHKKVAMFCTGGIRCEKSTAYLKEQGFEEVYHLEGGILKYLEEVKQEESLWEGECFVFDNRVAVDHDLKKGQYDQCNACRMPITEAEKLSPAYVQGVSCPHCIDKISDEQRKRFVERERQVNLAKSRNEAHIGSDVNQVIEARRQKKEALRQQSAEKNKAKQ
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: PURT_CUPTR
Sequence: MTTLGTPLSPSATKVMLLGSGELGKEVLIALQRLGVETIAVDRYDNAPGQQVAHHARTIAMSDPDQLKALIEAEKPHLVVPEIEAIATPMLETLEAAGTVRVIPTARAARLTMDREGIRRLAAESLGLPTSPYKFCDSLEELQAAIDGGIGYPCVVKPVMSSSGKGQSKIDGPEGVKAAWDYAMAGGRVSHGRVIVEGFIDFDYEITLLTVRAIGASGQVETRFCAPIGHVQVSGDYVESWQPQPMHPAALASAQRIAQAVTADLGGMGLFGVELFVKGEQVWFSEVSPRPHDTGMVTMATQWQNEFELHARAILGLPVDTTLRSPGASAVIYGGVEAQGVVFDGVDQALRVPQTEVRLFGKPESFARRRMGVALAYADDIDTARTRAKEAASRVRPRAVG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: TTCA_RHIME
Sequence: MELAQSSPDETDSVIVDDAAFEGAAHPLFSRMPSSVSFNKLRKRLLRQVRQALDDFGMLKGSRRWLVGVSGGKDSYSLLALLMDLQWRGLLPVELVACNLDQGQPNFPKHVLPDYLRSIGVKHRIEYRDTYSIVKEKVPAGATYCSLCSRLRRGNLYRIGREEGCDALVLGHHREDILETFFMNFFHGGRLASMPAKLLNDEGDLTVLRPLAYAAEDDLAKFAAAMEFPIIPCDLCGSQDGLERNAMKAMLADIERRMPGRKDTMLRALGHVNASHLLDPKLFDFQSLSPEPKE
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PYRAR
Sequence: MPGKKSPYGLFAGGKLKRKRKRFKWNDVTYKRKMLGLVEKYDPLEGAPMARGIVLEKVGVEARKPNAAVRKCVRVQLVKNGKVVTAFVPLDGSLNYINEHDEVVIERIGGPEGRSLGDIPGVRFKVIKVNGVSLWAIWSGKKQKPTR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NSRR_VIBPA
Sequence: MQLTSFTDYALRTLIYLASLPKDELTNITEVTDLFGVSRNHMVKVINRLGQLGYVHTVRGKNGGIRLMKPASEITVGGVVRDLEPLDLVNCGVEFCHITPACRLKDKLAKAKSAFLAELDECTIESLLSDNSELLILLARP
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: CP2A3_RAT
Sequence: MLASGLLLVASVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNYLQLNTEKMYSSLMKISQRYGPVFTIHLGPRRVVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSSGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIESFRKTNGALIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEQNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDIEAKVHEEIDRVIGRNRQAKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFREFLLPKGTEVFPMLGSVLKDPKFFSNPNDFNPKHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFCFKSPQAPQDIDVSPRLVGFATIPPNYTMSFLSR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2A3, CYPIIA3, Coumarin 7-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: IAPP_BOVIN
Sequence: MGILKLPVVLIVLCVALNHLEGGGKPTESHQMEKRKCGTATCETQRLANFLAPSSNKLGAIFSPTKMGSNTYGKRKKVEILKREPLSYLPI
What is the function of this protein?
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
What are the official names of this protein?
Islet amyloid polypeptide, Amylin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COBQ_PROA2
Sequence: MKNLAVFGTASDVGKSVIATALCRIFSNEGIDVAPFKAQNMSNNSGVTPDGFEIGRAQVVQAEAARVVPTADMNPVLLKPNTDTGAQVVLQGKAVANRSARDYFGNTRPWAEAAFESLRRLQAAHDMLVIEGAGSCAEMNLYDRDFVNFKTAEAADAPVILVADIDRGGVFAQVIGTVSVLPPEAKARISGVLVNRFRGDISLFEDGVRFLEEHSGIPVLGVVPFFRGFSIDSEDAVPLQTIVDPSGSPDPGKISIAVIYFPHISNFTDFAVLEREEGVELHYLHHAKALDGYQAVILPGSKNVRGDIEWLRQQGWESRLEDFRRNGGVIAGICGGYQMLGRSIADPYGVEGVPGRTAGLDLLPVETVLQQEKTLCNARGVMSGNGYSVHGYEIHMGETSCHGDALPLFDVTTRNGIAVSARDGVMTSDTKVFGTYFHGVFDAPLFRHWFFRQLSASYTPSERTEDRDEDYNRLARHVAAHLDLDKLYRIIEK
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: Y1093_OLEA2
Sequence: MVARRAAGSCPAHIAAGRLGEEAACAYLAASGMRILARNWRAGHLELDIIAQDNGTIVFAEVKTRAARGLESPHEALTPAKRSRLVRAAGMWLSSNDMWDRPCRFDLVCVTTEARAPEPEQMSLQAARAAGTAQARRAAGSGLPGILGKAASRLFGAGSPQRSHRAGGAPDSPEQLLRVEHIPHAFDLSESLGGGDAAWQPW
What are the official names of this protein?
UPF0102 protein Dde_1093.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: PROB_TRIL1
Sequence: MRRGLLQQVRRVVIKVGSRVLTVEGGGLDYDAISRLCDEMAGLRQQGIEVILVSSGAVAAGRDALRSADTTLTIPQKQAAAAVGQPLLMQAYQQACTRHGLVTAQILLTAEDLANRNRFLNARTTLEALLTAGALPVINENDSVAVAEIKFGDNDNLSALVTSLAEADLLLILTDIEGLYSANPASDPDAELIPLVRSITREIERMAGGSGSNVGTGGMATKVTAAKKAARFGVPTILAPGKQPGVITAAVSGQEIGTLFLPATDGLNRRKHWIAYTLRPAGKVLVDAGAQKALVEKGTSLLPSGITGVEGRFERGRCVRICGPDGTEIARGLADYSSSEIQLIAGHKSAEIEQLLGYRYGDDVVHRDNLVLMTHS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLAB_PARD8
Sequence: MKWYLWGAVVLLYSLFGSACSTEWRYDLSAYGLSPVENVDNAPAMARALEQIREKCEENQTIVVTLPKGRYEFYPDSAAERVYFISNHDQMNPKKVGLPFEGMKNMVFDGQGSELIFHGRMLPVSLLDSRNCVLKNFSIDFKHPQISQVKVVENDTVNGGITFEVAPWVHYEIRDSVFVAKGEGWELTPGSGIAFEGDTRHLVYNTSDIPVGVRGLIEVSPRLIKSPRWKDNRLVPGTVIAMRSWERPAPGVFLYHDVNTTLENIKVHYAEGMGLLAQMSENITLDGFSVCLKGADDPRYFTTQADATHFSACKGAIISKNGLYEGMMDDAINVHGTYLKVVRRVNDSTLVGRYMHPQSYGFEWGRVGDSVQFIHSSTMELIGARNRITAIKAVDQPDYRGAKEFEIRFENTVNPSIHEGSGFGIENLEWTPTVLFSDNLIRNNRARGSLFSTPRQTVVENNVFDHTSGTAILLCGDCNGWFETGACRNVLIRKNKFINSLTNMFQFTNAIISIYPEIPDLASQRKYFHSDIVIDANEFITFDRPLVYAKSVDGLVFTNNIVKQNKEYPAFHWNNYRFYFQRVIHSKIENNYFDEGFIRERDVLEENNGYDI
What is the function of this protein?
Alpha-galactosidase.  Removes both branched alpha-1,3-linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures.
What are the official names of this protein?
Alpha-1,3-galactosidase B, Exo-alpha-galactosidase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 110 family. B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TM135_RAT
Sequence: MAALSKSIPHNCYEIGHTWNPSCRVSFLQITWGALEESLRIYAPLYLIAAVLRKRKLEYYLYKLLPEILQSASFLTANGALYITFFCVLRKILGKFYSWTPGFGAALPASYVAILIERKSRRGLLTIYMANLATETLFRMGVARGTITTLRNGEVLLFCITAAMYMFFFRCKDGLKGFTFSALRFIVGKEEIPTHSYSPETAYAKVEQKREKHRGTTRAMSLIALVRSLVDSICKHGPRHRCCKHYEDNCISYCIKGFIRMFSVGYLIQCCLRIPSAFRHLFTEPSRLLSLFYNKENFQLGAFLGSFVSIYKGTSCFLRWIRNLDDELHAIVAGFLAGVSMMFYKSTTISMYLASKLVETMYFKGIEAGKVPYFPQADTIIYSISTAICFHAAVMEVQNLRPSYWKFLLRLTKGRFALMNRKALDVFGTGASREFHNFIPRLDPRYTVVTPELPIDFS
What is the function of this protein?
Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission (By similarity).  May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L (By similarity).  May be involved in peroxisome organization (PubMed:17522052).
What are the official names of this protein?
Transmembrane protein 135, Peroxisomal membrane protein 52, PMP52.
What is the protein family that this protein belongs to?
Belongs to the TMEM135 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein.
Protein: HIS7_HYPNA
Sequence: MRLRQFIWLSMTQTRTADVSRSTKETEISVSVNLDGTGKADIETGIGFFDHMLDSLARHSLIDLKVRCKGDTHIDFHHSVEDTGIVIGQAIAKALGDFGGITRFGHAYIPMDETLTRASVDLCKRPYLIWKVEFRRDKIGEMDTELFKEFFHALAGNGGMCLHVENIYGENNHHIAESCFKATARALRTAITVDPRLGGKPASTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROZ_HUMAN
Sequence: MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN
What is the function of this protein?
Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles.  Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.
What are the official names of this protein?
Vitamin K-dependent protein Z.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_BORDL
Sequence: MSVRIRLKRMGAKKRPYYRIVVMDSSSPRDGRAIEELGYYHPVERQNQVKINKNKFQEWVDKGAIPSDTVKRILNKSNFKVDN
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ILVD1_ACIAD
Sequence: MPDYRSKTSTHGRNMAGARGLWRATGMKDEDFGKPIIAVVNSFTQFVPGHVHLKDLGQMVAEQIQAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPVVFVSGGPMEAGKVKFRGNEKAIDLVDAMVVAADDSYTDEEVQAFERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSIVATHANRKKLFLKAGELIVSLAKRYYEQDDSSILPRSIATKAAYENAMTLDIAMGGSTNTVLHLLAAASEAEVDFTMDDIDRLSRNVPVLCKVAPAKQDVHMEDVHRAGGIMSILGELDRAKLLNTTVSTVHEKTLQDALNKWDIIRTEDADVYEFFRSSPGGVPTQVAFSQNRYYSTLDGDRENGVIRNAEHAFSKDGGLAVLYGNIALEGCIVKTAGVDESILKFNGTARVFESQDAAVEAILGNEIKAGDVVVIRYEGPRGGPGMQEMLYPTSYLKSKGLGKDCALITDGRFSGGSSGLSIGHISPEAAEGGAIGLVEDGDLIEIDIPNRSMNLKVDDETLAARRKAQDEKGWKPVEERKRKVSKALKVYAMHTTSAAKGAVRIL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 1, DAD 1.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CODY_STAA2
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHSEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PR1B3_ARATH
Sequence: MMANPPTLPISDHSGGGSQSQQPVSTPAFRTFLSRLSSSIRQSLSQRRPWLELVDRSAISRPESLTDAYSRIRRNLPYFKVNYVTIVSLVLALSLLSHPFSLLVLLCLFCAWIFLYLFRPSDQPLVVLGRTFSDRETLGVLVILTIVVVFLTSVGSLLTSALMIGFGIVCLHGAFRVPEDLFLDDQEPANTGLLSFLSGAATSAAVAAASTPASGRV
What is the function of this protein?
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
What are the official names of this protein?
PRA1 family protein B3, AtPRA1.B3, Prenylated Rab acceptor 2.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.