PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_SALSV
Sequence: MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGAISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS12_RHORT
Sequence: MPTINQLIRKPRKAVVKRNKVPAMQACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGVLDTQGVKDRRQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MRAZ_DESAH
Sequence: MFRASSFHTIDPKGRIIVPARFRDDIRAGGADGVMVSILDKALYAYTFNEWQAIEKKILSAKSEPMRRFKRFFLGNACECLCDKQGRILIPPSIRAYAGLEKEIVLVGMLDHFEIWSREQWDRENNLMEEELEKKEVREAIASLGL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MURE_RICBR
Sequence: MTPTLKQLFEKHNVKGLSNNSKTIKANDAFFAIKNGNDFIADALEKGAALVITDDKKNTTNKVIFVEDIKETLHEAIELFYPKKPKTMIAVTGTNGKSSVVSYIAQIYSLIGQKAASIGTIGVEVFGIDNFNESIGGLTTTDYLSFRKIAHKLAKNGIDYLAFEASSHGLDQQRLGDLKVNVACFTSFSQDHLDYHHTKENYLLAKLKLFTDHLAKDGIAILNSDIEEIKFIKDYLDKHKIKYLCVGANGNCKITKTNSSLKGQNINFIFDNKNYDFDTPIIGSFQASNLLIAGPSVYYTSFDFSKVINALTKVKAVKGRMERVNRTNIFIDYAHTPDALEKALTELKNIKAKGGKLSIIFGCGGNRDTTKRKLMGKIAASIADNVIVTDDNPRHEDPKAIRQEIISGIVTTNYIEIADRKEAIKYGINNLKKDDILLIAGKGHENYQIIGDEKIRFDDAEVASMSFLATAGIQ
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHPD_ANASK
Sequence: MATLDAIREALPEPARDIKLNLQAVLQPGTLTPAQRWGVAVATAAAARNERLLAAVLADARAEVEPAVVEDALAAAAVMAMNNVYYRFRHMVGKASYAEKPARLRMNRLVKPAASKVDFELFALAVSAVNGCETCVRSHEQVVVAGGLSEDQVHEAVRIAAVLHAAAVSLELAGYAAVPSAAAAAG
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: AC11_NPVAC
Sequence: MSLAAKLIIYNYYAKYNEVHDVYGESYHHYRIVQEYLSESYVNGMSCIERDVTAMRRLKSGSCTFDEAVKMIDAGDSIKSLSHWFSTSETMGIDDNVREVLEQIDAVVPVSVRVQNGWQIFSLNNFEREISQDMLDCLQIILGRFEYFMRNGKLLRIANVFNPNNDVVGWWYNKFCVVTYVHRIMYRSVPAELVPRLSEAVKKFIRLRKSDYDDRLHVDESYNCPRVIAEMYGRFCGIGKEHFSKHKLSCMHILFQYLRGKTTQEEKSFPCYRVIKDFGRQCKDVYKNLKDVFDLLHAHSMSDKDKNSLMDLLCVMDCEEIDVDCFYYIFESFLNNKHLQ
What is the function of this protein?
Plays an essential role in nucleocapsid egress from the host nucleus to form the budded virion (BV).  Does not participate in nucleocapsid formation.
What are the official names of this protein?
Protein AC11.
Protein: DBHA_VIBPR
Sequence: MNKTQLIDFIAEKADLSKAQAKAALEATLDGVTDALKEGDQVQLIGFGTFKVNHRAARTGRNPKTGAEIQIAAANVPAFVAGKALKDAVK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MAP1_XENTR
Sequence: MAAVESRVCETEGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWASHKLLHKKAKDDKIKPETSPWTMDGDINTDPWPGYRYTGKLRPHYPLTPMRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKILSTEDIEGMRVVCRLAREVLGVAAMMVKSGITTEEIDHAVHLACISRNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQDGDIVNVDITVYRDGYHGDLNETFYVGDVDEGAKRLVETTYECLMQAIDEVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKPGHVFTIEPMICEGGWQDETWPDGWTAITRDGKRSAQFEHTLLVTETGCEILTRRLEENGRPHFIS
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 1, MAP 1, MetAP 1, Peptidase M 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFA_ASPOR
Sequence: MPVSLHPLVDNGITKGDANFPGGNLYCLCPQNKVTVAIKGNVAHNHACGCSKCWKPAGALFSVVGVVPKENLSVAANADKLEILDKAAAIQRYACKECGTHLFGRIEIDHPFKGLDFVHAELSDKKGWQEPQFAGFVSSIIEQGFHPNGMDEVRSKFQSLGLQTYDTLSPPLMDLIATYTGKKNGKLSANL
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Putative glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: CMOA_HAES1
Sequence: MNKDCIFAAPIEKLGDFTFDENVAEVFPDMIQRSVPGYSNIITAIGMFAERFVTANSLVYDLGCSRGAATLSARRHITQPNVKIIGVDNSLPMVERCRQHINAYQSDIPVEILCDDIRNIKIENASMVILNFTLQFVPQQDRQLLLEKIYQGLNPNGGLVLSEKFRFENKKMDDLLIDFHHQFKRANGYSELEVSQKRTALENVMRTDSIETHKERLKSAGFSQIELWFQCFNFGSMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: LDH1_BACCZ
Sequence: MKKGINRVVLVGTGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPAPTRVWKGSYEDCKDADLVVITAGLPQKPGETRLDLVEKNAKIFKQIVRSIMDSGFDGIFLIATNPVDILTYVTWKESGLPKERVIGSGTTLDSARFRYMLGEYFNIGPHNIHAYIIGEHGDTELPVWSHVSVGIQKLQTLLEKDNTYNQEDLDKIFINVRDAAYHIIERKGATYYGIGMSLLRVTKAILNDENSVLTVSAYLEGQYGQKDVYIGVPAVLNRGGVREILEVELSEDEELKFDHSVQVLKETMAPVL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRAA_BACSU
Sequence: MSKKIAVLVTDQFEDIEYTSPVKAYEEAGYSVVAIDLEAGKEVTGKHGEKVKIDKAISDVDASDFDALLIPGGFSPDLLRADDRPGEFAKAFVENKKPVFAICHGPQVLIDTDLLKGKDITGYRSIRKDLINAGANYKDAEVVVSHNIVTSRTPDDLEAFNRESLNLLK
What is the function of this protein?
Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins.
What are the official names of this protein?
Putative cysteine protease YraA.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: MDH_NATPD
Sequence: MTKVSIIGAAGTVGAAAGYNIALRDIADELVFVDIPDQRETTIGQAADANHGIAYDSNTTVVQGEYEDTAGSDVVVITAGIPRKEGQTRIDLAGDNAPIMEDIGASLDEYNDDYVSITTSNPVDLLNRHLYEAGDRDRHKVIGFGGRLDSARFRYVLSERFDVPVQNVEATILGEHGDAQVPVFSKVRVDGADPEFDGDEKEEILGDLQESAMDVISRKGATQWGPATGVAHMVEAVLNDTGEVLPGSLVLDGEYGYEDTAFGVPVKLGANGIEEVVEWDLDDYESELMDDAAEKLSDQYDKIS
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: PP15_ARATH
Sequence: MAQQGQGSMDPAVLDDIIRRLLDYRNPKAGTKQAMLNDSEIRQLCFVSREIFLQQPCLLELAAPVKICGDIHGQYSDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNVKLWKVFTDTFNCLPVAAVIDEKILCMHGGLSPELINVEQIKNIERPTDVPDAGLLCDLLWSDPSKDVKGWGMNDRGVSYTFGADKVAEFLIKNDMDLVCRAHQVVEDGYEFFADRQLVTMFSAPNYCGEFDNAGALMSVDESLMCSFQILKPVDRRSRFF
What is the function of this protein?
Serine/threonine-protein phosphatase that possesses phosphatase activity toward para-nitrophenyl phosphate (pNPP) in vitro.
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1 isozyme 5, Type one protein phosphatase 5.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: END4_BIFLS
Sequence: MTELYIGSHLSTAGGWNALLERSHEEGGTAFAFFPRSPYGKRSKALDPADAATFGARLKAEDYGPLVVHAPYVYNLAGKDEAKRAFAIEALAEDIELLTAIREAGQEVYINIHPGAHVGQGTKTGCQLISEGLNQVFERTTGVMVLLETMAGKGTECGRNFEELATIMNGVKNKANVGVTFDTCHVLDAGYDLVNDYDGVMRQLDEAIGLAKVKAIHVNDSQFGLDSHKDRHANIGQGQLGIPFFTRLVNDPIMAKLPMILETKEQTPATHRDEIELLRGLVQK
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: C27AA_BACUH
Sequence: MNPYQNKNEYEILDAKRNNCHMSNGYPRHPLANDPQMYLRNAHYKDWLSMCNKNNPVGLIPPESFEWTWLNGTVAALTIVSVIAGILVTAPVSVTAGLITVLGAGAALLAGITPLIWPATTDNTFNKITDATEVLLNKEISEFVRKTANTKIDSLQQLIYYYQNALENWKKNPNDSAARNTVSTRFQIVNAFFVEAMPALSMPGYEVVQLGAYAQAANLHLILLREGIAYADQWNLARDPMHAAGDLHYKEFLDYRNQYINHCSTWYNEGQNEANLKNNGLVYQRTMTLFVLDLIAMFSTYDPRLYTMPIKTEILTRTIYTDGVNRNEPKSIHNPGLFRRLEQMKLHIYEYQGAQFLSGHQNIFRSMNYNHPLIYGPVQGYSSSNINKITTINLGDYDKIYSINTESRNRLVQGSTTFDKINFYGAFNENWLFSVYNQNGPIIKHSNIPGIDAPSTGLNYSNYTHYLSNCIFQSNRNGGSAPDYNTQSYVFGWNHYTIDPTGNYVTDAFEVNKNLPESRYVPQISQVPAVKASDIFNPGRVVNAKVESGPYFTGGDVIVSKAQLDGSGLARTLITFPIIPKRYRASGFRVRMYYAANHTGQVSYGVANINTTGYANFQKTFDGWEYFRARHEHFKYIEFDTTFSLRNSGQLEEHLLHIYYPNTTKISGDQLLIIDKIEFIPVGIPLNQTSEGYNTYDQNTNSYNQNYNNYNQNMDTTYQPNYDNYKQNSSGMYDNPYNQNPKDSYNQNYTDTYDSGYNNSQNVGSNYNQEYNTYNQDTENMYNQSYNNYNSDNNNYNQNSDCMCSPGYNGNYECRCNQRANGNYPK
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.
What are the official names of this protein?
Pesticidal crystal protein Cry27Aa, 94 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryXXVIIA(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: HIS1_THEGJ
Sequence: MRFVLPKGRLLRGSLEILRRAGYEIDEPGERRLIQRFNGNEVLLARAFDVPVYVEHGVDVGITGSDVVEERGSDVFVPLDLPFGKCRLSLAMPRESVTPPEDMDGYRIATKYERITRNYFSSLGVEVEVIKLSGSVELAPKVGIADAIVDIVETGTTLRANGLVEVDKVMDVSAQLLVNRISQKTKFDEINSLVLAIKEVVKDGA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_HAEIN
Sequence: MLTALNRYWDYLRIERQMSPHTITNYQHQLDATIKILAQQDIHSWTQVTPSVVRFILAESKKQGLKEKSLALRLSALRRFLSFLVQQGELKVNPATGISAPKQGRHLPKNMDGEQVQQLLANDSKEPIDIRDRAILELMYSSGLRLSELQGLDLNSINTRVREVRVIGKGNKERVVPFGRYASHAIQEWLKVRALFNPKDEALFVSQLGNRISHRAIQKRLETWGIRQGLNSHLNPHKLRHSFATHMLEASSDLRAVQELLGHSNLSTTQIYTHLNFQHLAEVYDQAHPRAKRKK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLT_SALSV
Sequence: MSESVRTNTSIWSKGMLSVIVAQFLSAFGDNALLFATLALLKAQFYPDWSQPVLQMVFVGAYILFAPFVGQIADSFAKGRVMMVANGLKLAGAAGVCLGINPFVGYTLVGIGAAAYSPAKYGILGELTTGDKLVKANGLMEASTIAAILLGSVAGGVLADWHVIAALVACALAYAGAVAANLFIPKLVAARPGQSWRLSAMTRSFFCACVVLWRNGETRFSLVGTGLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAVGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVAIFSLQHALLPAYALLLLIGMLGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGLYSLAVLVGVPAVAIGIGFGVLFALAIAALWIWQRRQASY
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTMR3_CAEEL
Sequence: MTVTSSAAIDIGGGGGGRRSDRLDSDRTSEDMSFIASPANESFQIGASFVDVQNESSGSIDTATATLHELNYTFGMPPVTEESENMPQNYETVVELLPGEERAPINKLTEFPIEGGSLFVTNFRIVVILKDKEVEEALRFLVFPLQDIEQIDLAIPAFIHLSLKIGRMFTICFKTAEDAALVHKILYTAFQRLNRPISSIYTSRPQDWTSKNTDNPMQSLNAFAWKFSEAVDELDRDGKLPSWLLRADSVAQEITHIDFNRLGMSEHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVGILSWRNPTDEKIIEEAVKASRIEGEEKKQFIIMDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPNEQLLTSLQTTGWLLNLSNLLVNAANCADHLSKGHSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRQLVAFGNWGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLIKLAKHAYSGLFGSFLFNSHKERREAMEKCKGTLVDIWRFIGPHNEEYVNQSFDEHYTGAVKPVNVSVINLRVWHEVFADEEEHYTQIFSPKEERPLSGCTTPMNTSTSTNLVKSKSSESINSLNVDGSAKESSQQHPTCSTTPSDNTNSLPMSTSFIQQSLYQPKVRGVAAIDRDGVIRFEDDEQAMLRKKNKLRAEEIRRKDEKIEELRRRAVLDTNKVSPGQRQSYSESDVETTGTLERVMSDVSMVDPVNELPHFKPNTTWEGESGHCAYCKKEFNKLSVYVEDRQHHCRNCGRVVCEDCSKNRFSVIEEGKSVQKRACDSCYDSMHETDLKLSSSSTTTTSSSTKIENDSNVPGLDNNSDNVSENVSENAIPDIIVEEKEAEDPIKEAESPSKETKCPKTLRNFISFSPKSSMRKNKVHSRDPLKSIDEGSSSQQAESDDVLDVNEQPL
What is the function of this protein?
Preferentially dephosphorylates phosphatidylinositol 3-phosphate (PI3P), and has some activity towards phosphatidylinositol 3,5-bisphosphate (PI35P) (PubMed:18393358, PubMed:25124690).  May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues (By similarity).  Positively regulates autophagy and is recruited to autophagosomes by PI3P where it catalyzes PI3P turnover to promote autophagosome maturation (PubMed:25124690).  Thought to have a role in maintenance of muscle function (PubMed:18393358).  Involved in locomotion and lifespan determination (PubMed:18393358).
What are the official names of this protein?
Myotubularin-related protein 3, ceMTM3, Myotubularin homologous protein 1, ceMTMH1, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: SYDND_CALS4
Sequence: MGEQLGGLKRTHMCGELGVKDVGKSVVVMGWVNSRRDHGGLVFIDLRDRTGIVQIVFSEQVSKEVFEKVQSVRSEYVLAVEGEVVKRLPENVNPKIPTGEIEIYAKNLKILSKSETPPFPIEDRSNVSEAVRLKYRYLDLRRPSMQRNLITRFKLTQAVREFLNDNGFIEIETPMLIKSTPEGARDYLVPSRIYPGKFYALPQSPQIFKQLLMIAGFDRYYQIARCLRDEDLRADRQPEFTQIDIEMSFVEVEDVLDINERMIKHVFKKVLDVDLDIPFRRLTYQEAMERFGTDKPDLRFGMELKDLSDILRESEFNVFKNALKNGGSIRGINVKGAASMTRKQLDELVEFAKNFGAKGLLWMQVLEGEVKSPATKFLTEGELNKILERLEAEVGDLLLIVADKDEVVFDTLGHLRVEMAKRFNLIDESKYEFVWVVDFPLLEYDEEEKRYVAKHHPFTSPKDEDIDLLEKEPLKVRAKAYDIVLNGTEIGGGSIRIHDTELQKRMFKVLGFSEEEAWKKFGFLMEAFKYGAPPHGGIAYGLDRLAMIMTGSDTIRDVIAFPKTQNAVCLMSDAPSEVSEKQLKELHIKIDL
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNC_LEPBP
Sequence: MQIKHNLLDIEGTTAPIAFVHQILFPYATKNIHRFLKEYQLTELQWKEVQTEFQKDTSSGDPLFIEKFRIKNVPSGLIVNEVPNTLSKDMVSVYFEYLIEKDRKFGPLKEIQGKIWKEGYESGEIKSTVFDDVPKFLNDAIQSGIQNHVYSSGSVEAQHLIYQYSVLGDLRQYFTMYFDTAVGGKREKTSYERIASTLAVSPSEIRFFTDIVEEAEAANATGMDVVILNRPGNLAQKPHPFPVWEHF
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: FIBA_ANAPL
Sequence: QDGKSSFQKEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH1_CLOPS
Sequence: MNITVISVGKLKEKYLKQAIDEYSKRLSRYCKLEIIELPDEKTPDNASEKEELQIKEKEGKLILSKIKDNMHVIAMDLKGNEITSEKFSKYIENCGVMGNSNITFVIGGSLGLSQEVIKRADYKLCFSKMTFPHQLFRVMLLEQVYRAFRIMKNEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H 1, 23S rRNA (pseudouridine1915-N3)-methyltransferase 1, 23S rRNA m3Psi1915 methyltransferase 1, rRNA (pseudouridine-N3-)-methyltransferase RlmH 1.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_YERPG
Sequence: MYAVFQSGGKQHRVSEGQTIRLEKLDIATGETIEFDQVLMIANGEEINIGAPLVDGGKIKAEIIAHGRGEKIKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: UREG2_STRGG
Sequence: MRHGHPPTDIHHGINQGEPMDDNVLRVGIGGPVGSGKTALIEALVPVLIERGHRPAVITNDIYTQEDAQHVRRTLAGVLEPERVVGVETGACPHTAVRDDPTMNLAAGAEMLERFPDTDTLLYESGGDNLTLTFSPALVDLFLFVLDTAEGEKMPRKRGPGITESDLLVINKIDIAQYVRTDIGIMEADAHRVRDDRPVVLTDCLTGVGIDDIALYLESRRKVLI
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 2.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YD172_YEAST
Sequence: MLFQLNIVFKELKNPDFFFFFFFFSLPLSSFKLNLSSSSSFKLWLIVFLLDFGEIMFPAPPLPIANFSGALLPLSLFLGFLDVDLIAAKALPLEVTTNRLSSFALIVSSSSILPPRISSSSFPPLLATFFLLKKMFPAPPLPTTIGALLFGDEVVACKD
What are the official names of this protein?
Putative uncharacterized protein YDL172C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIS8_RHORT
Sequence: MTKAIIPQPRPGIMEISPYVGGESKLAGVDRIIKLSSNEGALGASPRVRDALIASAGEAHRYPDGNATALREALGRTHGLDPARIVCGAGSDELIGLLCRAYAGPGDSIVQSAYGFLMYGIYARGVGAEPILAPESDLTADIDAMLAAVRDTTKLVFLANPNNPTGTCLPTSEVVRLREGLRDDIILVVDAAYAEYVERNDYDAGARLVDSHPNTVMLRTFSKIGLGGLRLGWSYGPAHIIDVLNRVRGPFNICGQALVAGEAALADPAFTDLSRAHNSLWREWTRAKLQAMGIRVGESSGNFVLATFDAEGPFTALAADAALRQQGIICRRVAGYGLPNCLRITIGRDDEMQAVVEALGAFMAGEGR
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RL1_GEOSE
Sequence: MPKRGKKYLEALKLVDRSKAYPIAEAIELVKKTNVAKFDATVEVAFRLGVDPKKADQQIRGAVVLPHGTGKVARVLVFAKGEKAKEAEAAGADYVGDTEYINKIQQGWFDFDVVVATPDMMGEVGKLGRILGPKGLMPDPKTGTVTFDVAKAVQEIKAGKVEYRVDKAGNIHVPIGKVSFDNEKLAENFAAVYEALIKAKPAAAKGTYVKNVTITSTMGPGIKVDPTTVAVAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.