PharMolix/UniProtQA huggingface dataset:
Protein: RLMF_PSEAE
Sequence: MPRPTSPHPDAERKSASPLHPRNRHLGRYDFPRLIAGSPELERFVILNPYGRQSIDFADPAAVKAFNRALLQQFYDVREWDIPDGYLCPPIPGRADYLHYLADLLGASHDGLIPRGPGLRALDVGTGANCIYPLLGHHEYGWRFVGADIDPQSLASAAAILAANPRFAAAIELRRQPDRRQIFQGLIGVDERFDMTLCNPPFHASLDEATRGSRRKWKNLGKLDPTRTLPLLNFGGQGAELYCEGGEAAFLAGMAEESRAFATQVFWFTTLVSKASNLPNLQERLKTLGASDIRVVDMAQGQKQSRFVAWTYLDKKQRRAWRKERWTAALLEPLGE
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_SPIOL
Sequence: PAGHGARARTRDLFAR
What are the official names of this protein?
60S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: PUP_NOCFA
Sequence: MAQEQTKRTGGGDEDEGSAGPEAAGQERREKLAEDTDDLLDEIDDVLEENAEDFVRAYVQKGGQ
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: CYOE_NITOC
Sequence: MTTITLIRGALTNWREYLVLCKPRIVSLIVFTAIVGMFLSVPDLAPWRVFLFGTLGIGLGAASAAAINHLIDEKADAVMNRTQGRPLPTGKLSREQALAFAITLGLSSMIILYFLVNPLTAWLTLASMIGYGIIYTAFLKPATPQNIVLGGASGAMPPVLGWAAVTGELHVHAFLLFLIIFVWTPPHFWALALARREEYSRTKYPMLPVTHGVDFTKQQIVLYTFLLFAVSLLPFVSHMSGLLYLVGAIGLGGRFVYLTIVLYRNTSNELAMKTFGYSIVYLAALFAFLLVDHYLPKFL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZDH1_STAAS
Sequence: MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNPVDTKQRQMEVTQAPRVLGFDAIGTVEAIGPDVTLFSPGDVVFYAGSPNRQGSNATYQLVSEAIVAKAPHNISANEAVSLPLTGITAYETFFDTFKISHNPAENEGKSVLIINGAGGVGSIATQIAKRYGLTVITTASRQETTEWCEKMGADIVLNHKEDLVRQFKEKEIPLVDYIFCTYNTDLYYNTMIELIKPLGHITTIVAFNEDQDLNALKLKSITFTHEFMFARPIHRTPDMIKQHEYLEDITKNIESGHYQPTTTQVFEGLSPENLYQAHQLLEKQSMIGKLVINI
What are the official names of this protein?
Zinc-type alcohol dehydrogenase-like protein SAS2087.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: RL1_SYNC1
Sequence: MSIGKLHKQAKEKVDRSQVYPIGEALALVKEVAHAKFDETVEISVRLGVDPRKADQMVRGAVVLPNGLGKDVKVLVFAKGEKAIEAKEAGADYVGGDDLVAKIQEGWFDFDTAIATPDMMGTVGKIGRLLGPRGLMPNPKVGTVTFEVGKATSEAKSGKVEYRVEKAGIVHAPVGKVSFDAEKLQENLVALFDALVKAKPATAKGTYFKKMSLSSTMGPGINVDLPTVQALVK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NRFC_ECO57
Sequence: MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDESLCIGCTACMDACREVNKVPEGVSRLTIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVDVCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTNLQAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKYGEVSQ
What is the function of this protein?
Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes.
What are the official names of this protein?
Protein NrfC.
Protein: Y1013_VIBCM
Sequence: MSTPFWQSKTLDQMTEAEWESLCDGCGKCCLHKLMDEDTDEIYYTNVACSWLNSDTCSCKDYPNRFSSGEECLKLTRDKIEEFNWLPDTCAYRLLGNGQTLPEWHPLLTGSKDAMHAADESVRGKIVYEVDVIDWEDHIVLMSRD
What are the official names of this protein?
UPF0260 protein VCM66_1013.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: Y1308_PYRFU
Sequence: MILKPSKPYSFCFTTYPWKKLKLKEHSKVIIKIIDEEEIEKILDSMIIEKVEGIDYKKLKETHYESL
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Putative antitoxin PF1308.
What is the protein family that this protein belongs to?
Belongs to the UPF0165 family.
Protein: SPY2_CHLAE
Sequence: MEARAQSGSGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
What is the function of this protein?
Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2 (By similarity).  Thereby acts as an antagonist of FGF-induced lens retinal fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis (By similarity).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells (By similarity).  Inhibits CBL/C-CBL-mediated EGFR ubiquitination (By similarity).
What are the official names of this protein?
Protein sprouty homolog 2, Spry-2.
What is the protein family that this protein belongs to?
Belongs to the sprouty family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF (epidermal growth factor).
Protein: LPXK_RHIME
Sequence: MVSEAPPFWWTKADWRAYALWPFSWVYGRIAGMRMDRARRATSAVPLICIGNFTVGGAGKTPTAIAIARAARARGLKPAFLSRGYGGSLDVTTVVDPEHHRARDVGDEPLLLAREALTVICRRRVDGARKLAAEGADIIIMDDGFQSARLVFDFALLVVDSGRGIGNGHLVPSGPVRAPIGNQLRHANALLKLGHGSAADPLVRRAARAGKPVYVAETVRTDAGSLDGVKVLAWAGIADPEKFFKTVRETGAVIEETRSFPDHHHFSEDEIADLIDRAASRGYTLVTTAKDMVRLEPGHGRAGELAAKSRVIEIEVRFDDPAAPGKIIDAALASARARRLRERKAG
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: ARNB_PSEF5
Sequence: MNQAFLPFSRPSIGEEEIAAVEQVLRSGWITTGPKNQELEQQFAERVGARHAVALSSATGAMHITLLALGIGPGDEVITPSQTWVSTANMICLLGATPVFVDVDPDTLMSDAATIEAAITPRTKAIIPVHYAGAAFDLDPLYALADKHGIAVIEDAAHAAGTTYRGRAIGARGTAIFSFHAIKNMTCAEGAMFVSDDEALANRVRMLKFHGLGVDAYDRLTHGRKPQAQVIEPGFKYNLADMNAAIALVQLQRLDEINAKREVLAKAYLQRLEGLPVQPLLLPQYPQQHAWHLFILRIDAERCGLDREAFMKGLQEQNIGTGIHFIATHLHTYYRQRFPEVQLPHTEWNSARLCSIPLFPDMTLDDVERVTGAIANLLD
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: HRCA_LEPBA
Sequence: MDLSPRHRSILKALVEEFVSDNKPVGSKTLSEKYDIGLSPATIRSCLAELEDMGFIVARHTSGGRVPTERGYRLYVDSLVTLFELTMREKQRIQEEYLRMQFRLDQVLIATSKVLASLSQSASVVLGPEGSLDTLKHIELIHVNGGEVLMILVMRSGTVLNRNIFFDFHISQETLYQISRYLNDNVKGFDVHEIQSNLIPQMMLKKEGPEGFTLFAPSIARAMGTDSHSVDNLYIDGLKNLYENFKDEEEQLENILHLFDEKQFLKEFFSDYVPMDGVYTIIGKDGNEKLGGVTIITTNYRMGEKRIGSMGIIGPQRMNYNKALPLIEFTSKLVSEMITKLSR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: EFTU_FRATF
Sequence: MAKEKFERSKPHVNVGTIGHVDHGKTTLTAAITKVMAEKNGGMARKFDEIDSAPEEKARGITINTSHVEYESPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPKIVVFLNKCDMVDDEELLELVEMEVRELLDQYEFPGDDTPVIMGSALRAIEGDEAYVEKIVELVQAMDDYIPAPERDTEKPFILPIEDVFSISGRGTVVTGRIERGVVNVGDEVEVVGIRPTQKTTVTGVEMFRKLLDRGEAGDNVGILVRGLKRDDVERGQVLCKPGSIKPHTKFEAEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDITGAVELPEGVEMVMPGDNVKMTITLINPIAMDEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGAM5_CAEEL
Sequence: MVSKIIKLGVPTATLAVGTLLLGDDEKRSAFFRTASAFTQNHGHKTFDEHFPRGEWDKNWDFRDPISLVDKGKWEKADEEGKKKLIEEKKATATRNIFLIRHGQYHLDHEVKMLTPLGREQAELLGKRLANSDIKFTNMTMSTMVRATETANIILKHLPDDLTRTSSPFIEEGPPYPPVPDHKTWRPLDPEFYTEAARIESAYRKIFHRASPSQKEDSFELIVCHANVIRYFICRALQFPPEGWLRMSLGNCSLTWITIRPKGHVSVRSIGDIGHLPPNKISFT
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues.  Has apparently no phosphoglycerate mutase activity.
What are the official names of this protein?
Serine/threonine-protein phosphatase Pgam5, mitochondrial, Phosphoglycerate mutase family member 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: SYE1_MARMM
Sequence: MTKVRFAPSPTGKLHVGNVRTAIFNYLFARKAGGTFVLRIDDTDVERSTKAYEDGIRADLTWLGISWDETFKQSDRFDRYEAAAETLKAKGLLYPCYETGEDLDRKRRLQMANGRPPVYDRAALDLTDAEKAGFEAEGRKPHWRFKLSGNPVQWDDMVRGHVSIETSSLSDPILIREDGSFLYTLPSVLDDIESEITHIIRGEDHTTNSGAQIEIFEALGGKAPIFGHQALLVGADGGKLSKRTGSLGIADLRDVDGLEPMAIMSLLARIGTSDPVEAFADVEGILEGFDLGKLSRSPARFDDEELKRVNAKLLHAMPYDVAQPKLAVLGADKGEAVWEAVRPNLETLADAKAWAVLIDGPVTPVIEEPDYAAAAAQHLPAGELDGDSWSVWTNALKEATGRKGKQLFMPLRLMLTGEARGPEMAVLLPLIGRDKVLKRLAGEAA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_ACIBC
Sequence: MSNATKFGKVAVLLGGKSAERAVSLDSGQAVLDALLRSGVQAEAFDPQDRSVTELVNYDRAFIVLHGRGGEDGQIQGVLEWLNIPYTGTGVQGSAIGMDKVKTKQIWQGSDLPTAPYRIITKETDLDSVIAELGLPVIIKPVHEGSSVGMSKVEKAEDFAAAIEKATQHDAVVMAEKWITGREFTISFLNGQPLPVIRLQPPADVAFYDYEAKYQRNDVEYGIPCGLSETEEKKLQALCLRAFQAVGAEGWGRIDAMQDEQGNFWLLEVNTVPGMTSHSLVPKAAKAVGYSFDELCVAILEQTLEGTA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL_VZVD
Sequence: MASHKWLLQIVFLKTITIAYCLHLQDDTPLFFGAKPLSDVSLIITEPCVSSVYEAWDYAAPPVSNLSEALSGIVVKTKCPVPEVILWFKDKQMAYWTNPYVTLKGLAQSVGEEHKSGDIRDALLDALSGVWVDSTPSSTNIPENGCVWGADRLFQRVCQ
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: SC61A_PYRSA
Sequence: MGTSGVRFLTLVKPFMFALPEVSSATKKIPVNEKLLWTSIVVFLYLVCCQIPLYGITNTKSSDPFYWMRVILASNKGTLMELGISPIVTSGLVMQLLAGSKIIDVDQGTKEDKTLFQGAQKLLGILITIGESVAYVLSGMYGDVKDLGAGNAILIIVQLFTSGIIVICLDELLQKGYGIGSAISLFIATNVCESIVWKSFSPTTINTGRGTEFEGALVALFQLMITKTDKVRALQEAFYRQNLPNVTNLLATVLVFVLVVYFQGFQVELPITPAKSKGMAGQFYPIKLFYTSNMPIILQTALVSNLYFISQILYKRYPENIIIHILGRWEEPEMSVSGQMRPVGGIAYYISPLNSFAEIVSDPVHALLYIIFILASCALFSKTWIQVSGTSASDVSKQLRDQQMVMKGFRASSMQRELNRYIPTAAAFGGMCIGALSIVADFMGAIGSGTGILLAVTTIYQSWETILLAVTTIYQSWETIRKESRDTDALKMFG
What is the function of this protein?
Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER.  It is required for assembly of membrane and secretory proteins.
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DERL1_CAEEL
Sequence: MDLENFLLGIPIVTRYWFLASTIIPLLGRFGFINVQWMFLQWDLVVNKFQFWRPLTALIYYPVTPQTGFHWLMMCYFLYNYSKALESETYRGRSADYLFMLIFNWFFCSGLCMALDIYFLLEPMVISVLYVWCQVNKDTIVSFWFGMRFPARYLPWVLWGFNAVLRGGGTNELVGILVGHAYFFVALKYPDEYGVDLISTPEFLHRLIPDEDGGIHGQDGNIRGARQQPRGHQWPGGVGARLGGN
What is the function of this protein?
Specifically required for the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins.  Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.
What are the official names of this protein?
Derlin-1, Coelomocyte uptake defective protein 2, DER1-like protein 1, cDerlin-1.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RUVB_VIBPA
Sequence: MIEADRLIAPENPAFRDEDVIDRAIRPKKLADYQGQDHVRDQMEIFIKAAQLRSEALDHLLIFGPPGLGKTTLANIVANEMEVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGITQRLEYYKVQDLQNIVQRSADCLGLSMEPEGALEVARRARGTPRIANRLLRRVRDYAEVKGNGHICADVADKALNMLDVDAQGFDYMDRKLLLAIMEKFGGGPVGLDNMAAAIGEEKDTIEDVLEPYLIQQGYLQRTPRGRIATDRAYLHFGIEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ASSY_STRAW
Sequence: MQCEEKPVTERVVLAYSGGLDTSVAIGWIAEETGAEVIAVAVDVGQGGEDLDVIRKRALACGAVEAEVADAKDEFADEYCLPAVKANALYMDRYPLVSALSRPTIVKHLVAAAQKHGATTVAHGCTGKGNDQVRFEAGIVALAPGLKCIAPVRDYAMTRDKAIAFCEEKRLPIATTKKSPYSIDQNVFGRAVETGFLEDIWNAPIEDIYEYTSNPAEPREADEVVISFKEGVPVAIDGRPVTVLQAIQQLNERAGAQGVGRIDMVEDRLVGIKSREVYEAPGAIALITAHQELENVTVERELARYKRQVEQRWGELVYDGQWFSPLKRALEGFIDEANQHVNGDIRMTLHGGRAVVTGRRSETSLYDFNLATYDTGDSFDQAAAKGFIDIYSLSSKIAAKRDLA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_METEP
Sequence: MHDIRAIRENPEAFDRDLERRGLAPLSAELIALDDARKGAVSAAQAAQERRNALSKEIGAAKKAKDEARATELMAEVARLKEEAPGLEAAQGEAAKALDERLAAIPNRPKDDVPPGADEHGNVEYRRFDSSRERLAQGRQHFELGEATGLMDFEAAAKLSGSRFVVLKGQLARLERALGQFMLDLHTGEHGYTEVVPPVLVREEAMFGTAQLPKFRDDQFAAGENFWLIPTAEVPLTNLVRESILAEDELPLRFTALTPCFRAEAGAAGRDTRGMLRQHQFNKVELVSITAPEKSAEEHERMLACAEAVLQKLDLTYRVMTLCTGDMGFASQKTYDIEVWVPGQQTYREISSCSVCGEFQARRMNARYRAKEGRGVGFVHTLNGSGVAVGRALIAVMENYQNPDGSVTIPSALQPYMGGLTRIEGPKN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2_MONBE
Sequence: MADLQGKAVLTIAVPEAKADQIEAEILRLRAATTEAGSVQLEQFDRLEQVFLAPSSYDVIFSGHIALPAKSHADSALAKLAAALKPGGRLALRESLNSRNETALRSALTMGGFVNVQVSTSEHALEAHADKPVYEVGAAAPLKLSFAKKKQSGAAAPAAQVAEVWTIATDDFDDDDLLENDGDELLDAEDLALATTAPEGDDCEVGAGGKRRACKNCTCGRADAEAEQAAKPTLTGPLPASSCGNCYLGDAFRCASCPYLGMPAFKPGEKVTLSDRQLKADA
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: F16PA_BRUAB
Sequence: MTLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIARGYLPGDPGKLVGVNSDQDQQKSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGLVAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGNRQIAAGYVSYGNSVDLGFSVGEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGPRGRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGGKATDGSRPILDIVPQTYHERSALVFGVAEEVDILGEYFVK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_SALHS
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNLVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLTSVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEGLCEAAQEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHLMLEEGVYLAPSAFEAGFMSVAHSMDDINNTIDAARRVFATL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_BRASB
Sequence: MVERLSAEARTDALRKLSGWSELDGRDAISRSFTFRDFNEAFGFMTRVALVAEKRDHHPEWRNVYRTVDVVLSTHDAGGVTLLDVELAEAMDAIAASMA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: FIXS_RHIME
Sequence: MNTLIYLIPVALSLGGLGLVAFLWALKSGQYEDLDGASWRILDDGDGEGESSQTL
What is the function of this protein?
The four proteins FixG, FixH, FixI, and FixS may participate in a membrane-bound complex coupling the FixI cation pump with a redox process catalyzed by FixG.
What are the official names of this protein?
Nitrogen fixation protein FixS.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RS5_RICAH
Sequence: MSKVKKNEDTLSEVLVDVNRVTKVVKGGRRFAFSAYVVVGDKAGRVGAGHGKAKEVNEARGKAKQAAKKRMMKVPLYQNRTIHHDVVGKSGAAKVILRRAKAGTGVIAGGSMRAIFDSLGVHDIVAKSIGSTNVYAMISATFDALNKLASPKSIAMRRDKKVNEISIKSSDIQVNE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ISPH_MACCJ
Sequence: MEIIKITPRGYCYGVVDAMVIARNASLDKTLPRPIYILGMIVHNKHVTDAFESDGIITLDGPNRLEILEQIETGTVIFTAHGVSPEVKRRAKEKGLVCIDATCPDVENTHTLIRRKKADGYHVIYIGKKGHPEPEGAVGVAPDIVHLVENKQDIEQLPESLNDQKLIVTNQTTMSQWDVKHLMEDLEEKFPHIEVHKEICLATQVRQEAVANQAPSADVLIVVGDPKSNNSNRLAQVSKEIAHTEAYRISDISELKLEWLEGKSTIAVTAGASTPTPIVKEVIDYIKGYDPLNITPIPETSGVPVDKILPKIKNAAPVKILD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.