PharMolix/UniProtQA huggingface dataset:
Protein: METK_STAAN
Sequence: MLNNKRLFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVDIPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEATGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYDENDNPVRIDTIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLADQCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQPIYKQTAAYGHFGRTDVLFPWEKLDKVEELKDAVKY
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHPT_BRUA2
Sequence: MSLPVTLSALDLGALLCSRICHDIISPVGAINNGLELLEEGGADEDAMALIKSSARNASARLQFARIAFGAAGSAGVQIDTGDAQNVATEYFRNEKPEFTWEGARVLLPKNKVKLLLNMLLIGNGAIPRGGSLAVRLEGSDTDPRFVITVKGRMLRVPPKFLELHSGAAPEEPIDAHSVQPYYTLLLAEEAGMKISIHATAEDIVFSAE
What is the function of this protein?
Component of a regulatory phosphorelay system that controls B. abortus cell growth, division, and intracellular survival inside mammalian host cells.  This signaling pathway is composed of CckA, ChpT, CtrA and CpdR.  ChpT efficiently and specifically shuttles phosphoryl groups from the CckA kinase to the receiver domains of both CtrA and CpdR.  Does not bind ATP.  Overexpression of chpT results in a defect in cell morphology, DNA content, and intracellular survival in human macrophages.
What are the official names of this protein?
Protein phosphotransferase ChpT, Histidine phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the ChpT phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_HALH5
Sequence: MKPLILASGSPRRKQLLEQMNVPFTVCKSTIDETFDPTFPPDEVVQQLARQKAQDVAKKHEDSFILAADTIVVFQGRILGKPATEQEARQMLSQLSDQSHEVLTGVALLHQGQVETFVETTEVRFWPLTDTEIETYLQTGEPFDKAGAYGIQGLGAYLVKELKGDYYNVVGLPLSRTVRALKVHGFSTRF
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
Protein: DPPA5_HUMAN
Sequence: MGTLPARRHIPPWVKVPEDLKDPEVFQVQTRLLKAIFGPDGSRIPYIEQVSKAMLELKALESSDLTEVVVYGSYLYKLRTKWMLQSMAEWHRQRQERGMLKLAEAMNALELGPWMK
What is the function of this protein?
Involved in the maintenance of embryonic stem (ES) cell pluripotency.  Dispensable for self-renewal of pluripotent ES cells and establishment of germ cells.  Associates with specific target mRNAs (By similarity).
What are the official names of this protein?
Developmental pluripotency-associated 5 protein, hDPPA5, Embryonal stem cell-specific gene 1 protein, ESG-1.
What is the protein family that this protein belongs to?
Belongs to the KHDC1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPD_DANRE
Sequence: MHTVKLLCVVFSCLCAIGWASHHSHRQPCHSPQLTSGTMKVVSTGGHDLASGEFSYDSKTNKFRFVEDTTHANKTSYMDVLIHFEEGVLYEIDSKNESCKKETLQFRKHLMEIPVDATHESESYMGSPSLTEQGLRVRVWNGKFPELHAHYSLSTTSCGCLTVSGSYYGEKKDLFFSFFGVETEVDDLQVFAPPAYCEGVSFEEAPDDHSFFDLFHD
What is the function of this protein?
May play a role in neural plasticity.  May be involved during axon regeneration.
What are the official names of this protein?
Ependymin, EPD.
What is the protein family that this protein belongs to?
Belongs to the ependymin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_ECOL6
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation (By similarity).
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL3_METST
Sequence: MTRHHQPRKGSVAFSPRKRVARETPRVSTWPELDEAGLLAFAGYKVGMTHVTALDSRKGSPTENMELSVPVTILEAPPLVVLGIRAYTKTTYGLKTLTDVIANDNLDDELSRKISVPKFDDIEAKIEELRNKIDDIDEIRVLIHTKPKLTSVPKKKPEVLEFGLGGKSVEDKLEYAISILGKEITPQDVFQEGEYTDAIATTKGKGVQGPVKRFGVRIQYGKAARSGIERHVGSIGPWTPNRTMWTVAMQGQMGYHKRTEYNKKLLKIGDESEVDLINPDGGFVKYGFVKNNYILVKGSLPGPSKRLVVLRKGVRNASKQVTAPEISYISTTSKQGV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GATA_BARQU
Sequence: MTDLTTLTIAQARYALTKREFKATELTEAYLKAIELANPTLNTYVAITAEQAMKMATESDSRLARGQGGILEGIPLGIKDLFATQGVHTQACSYILDGFKPPYESTVTANLWRDGAIMLGKLNMDEFAMGSSNETSYYGPVINPWRKKGSNEKLVPGGSSGGSAAAVAAQLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGVIAFASSLDQAGPIGRNVRDCAILLKSMASFDEKDSTSVNLPVPDYENYIGQSIKGMEIGVPKEYYLEGMASEIVELWQKGINCLKEAGAKIIDISLPHTKYALPAYYIVAPAEASSNLARYDGVRFGLRVPGKDAIEMYENTRSAGFGDEVKRRILIGTYVLSSGYYDAYYLQAQKVRTLVKRDFDQCFASGIDAILTPATPTPAFGIADEKIKNDTVAMYLNDIFTVPVNMAGLPGISVPSGLSSTGLPLGLQLIGKPFAEEVIFQIAHIIEQAIGTFSTEKWWTQQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS17_SHEAM
Sequence: MSDKIRTLQGRVTSNKMDKSITVAVERLVKHPIYGKFIKRTTKIHAHDELNQCNEGDIVTIRECRPLSKTKSWTLVDVVSKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: MATK_ARTFM
Sequence: MEEIQRYLQLERSQQHDFLYPLIFQEYIYAFAHDRDFGRSILSENLGYDSKSSLLVVKRLISRMYQQNRFILSLDDSNQNPFWTCNNNFYSQTVSEGFAFIVEIPFSLRFKSCLEEKKIVNSQNLRSIHSIFPFLEDNFAHLNYILDILIPHPVHVEILVQNLRHWLKDASSLHLLRFLLNEYWNWNSLITPKKASSSFSKKNQRLFLLLYNSHVCEYEYFFVFIRNQSSHLRSTSSGVFLERIYFYEKIERLVNIFIKVKDLQANLWLVKEPCMHYVRYQRKSILASKGTSVLMNKWKCYLVTFWQWHFSLWFHPRRIYINQLSNHSLEFLGYLSSVRMNPSVVRSQILENSFLINNAIKKLETLVPIFLLIASLAKAKFCNVLGHPISKPVWADLSDSNIIDRFGRISKNLSHYYSGSSKKKSLYRVKYILRLSCARTLARKHKSTVRAFLKRLGSELLEEFLMTEEDILSLTFPKPSSALRGVYRSRIWYLDIIWINDLANYK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TIG_LACP7
Sequence: MSFKVEDLGKNMVKLTIEATAEDFDKAIEQAYQKNKGKMNVQGFRKGKAPRAIIEKMYGVGVFYEDAANFIIPEAYEQAIEESKLDVVARPEIDVVQVEKGQPFIFTAEVAVKPEVTLGAYKGVEVSKSEIEVTEDEIMAELDKVREQNSRTITVEDRAVMDKDIVTIDFEGFVDGVAFEGGKGEDYALTIGSHSFIDTFEDQLVGKNIGEDVEVNVTFPTEYHAADLAGKPALFKVKVKEIKAKELPAADDEFAGDVSEFNTLEEYKADLKKSLTEKKDKAAKTAKEDAVVDKVIENATMEIPDAMVDTQKRQMAEDFAQRLKMQGLSLEQYFQFTGLNPNTFMENLGPQALKRIQSRLVLEAVVKAENITVSVEEIDKELAEMASAYQMEVDKLKELIGEKEKEQIVMDMAVQKAIDLVASEAKEV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CYC6_RIPO1
Sequence: MKRLLSLIFLVFVFFAVMLTPPALAGDAAAGKTVFTAKCAQCHLGGKNLVNPAKTLSKADLEANGMASLDAIITQVTNGKAAMPAFGKLLTAEQIENVATYVLAQAEADWK
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: MTRH_METMA
Sequence: MFKFDKKQEVFELGGVKFGGQPGENPTVLVSTMFYARHKIVTDEDKGIFDRAAAETLWNTQVSLSDATGLPYVNQIVGETPESIKRYIEWFVGIDDRTPFLIDSSAGNVRAAAAQYCTEIGVADRAIHNSINASIEQSEIDVLTESDVSAAIVLAFNATDPTVKGKIDILEVGGSGQTKGMLQVAKECGIKYPIIDVAAMPLGAGSGATIRSVPTLKGKFGLPIGGGYHNMASAWDWLRKFKKTQPDPKAIYMPTDIGTNLVAQIAGSDYLLYGPIENVNQIFPAVAMVDIMLGETAKELGVEIADLENHPVTKLT
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.  MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit H, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit H.
What is the protein family that this protein belongs to?
Belongs to the MtrH family.
Protein: GPI_THEON
Sequence: MEYKAPIGVKIDLETGVIPGAKKLVRRLSDLKGYFIDEEAYNELLREDPVVYEVYAIEQEEKDGDLNFATTVLYPGKVGKEFFFTKGHYHAKADRAEIYYAIKGKGGMLLQTPEGNAKWVPMEPGTVVYVPPYWAHRTVNTGDEPFIFLAIYPADAGHDYGSIKEKGFSKLVIEEGGEVKVVDNPKWKA
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_CARHZ
Sequence: MGVPKRRVSKARKNKRRSQWKIAAPKLVSCPHCHQLMIPHRVCKNCGYYDGRQVVNME
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MEMO1_DANRE
Sequence: MSNRMVCREASHAGSWYTASGSQLNAQLEGWLSQAQSIAGPARAIIAPHAGYTYCGACAAHAYKQVDPSITRRVFILGPSHHVPLSRCALSPAEVYRTPLYDLRIDQKVYADLWKTGMFERMSLQTDEDEHSIEMHLPYTAKAMENHKDEFSIVPVLVGALSGSKEQEYGKLLSKYLADPSNLFIISPDFCHWGQRFRYTYYDESQGEIYRSIEHLDKMGMGIIEQLDPISFSNYLKKYHNTICGRHPIGVLLNAVAELKKNGIDMNFSFLNYAQSSQCRNWSDSSVSYAAGALIVH
What is the function of this protein?
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton.  Mediator of ERBB2 signaling (By similarity).
What are the official names of this protein?
Protein MEMO1, Mediator of ErbB2-driven cell motility 1, Memo-1.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: CRL_VIBC3
Sequence: MSEMTKTPTHYRLLSTLKAMGPYLREGQCSERFYLFDCLASCVNDKKSPEKREFWGWWMELTQNEQEMSACYHIGRYTLAGDWVAEAIPESAQAEVNHTQAEFHKKLVKTLRERFEISVTVSTESAPFA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_LATSS
Sequence: MQERHLFTSESVSEGHPDKIADQISDAILDAMLEQDPQARVACETTVTTGLVLVVGEISTTAYVDIQKVVRETIKKIGYRDGQYGFDGDNCAVIVALDEQSPDIAQGVDDSLESREKDEDPLDKIGAGDQGLMFGFAVDQTPELMPLPIALSHRLMRKVAELRKSGQLAYLRPDAKAQVTVEYDENEQPKRVDTVVISTQHDEDVTLETIQKDMLEQVIKTVIPAEYLDDKTKYFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLARKCEVQLAYAIGVAQPVSVSVNTFETGTVSEEAIQTAIRENFDLRPAGIIKMLDLQRPIYKQTAAYGHFGRTDVDLSWERLDKVDALKASIAKLNH
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I2B3_CONEB
Sequence: MMFRLTSVWCLLVIVLLNSAVDGFIPCTGSEGYCHSHMWCCNSFDVCCELPGPATCTREEACETLRIALGRRAQYKRFFRR
What are the official names of this protein?
Conotoxin Eb11.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: H4_MYTGA
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: UNC5_PETMA
Sequence: HREEQARYIVKNKPVTMSCAASPATQIYFKCNGEWLHQKAHHIEEREDETTGRSVREVQTDVSRQQVEELFGLEDYWCQCVAWSAAGTSKSRKAYVRLAYLRKNFEQKPLGKYALLDHEVLLHCRPPDAIPQAEVEWLKSEEIIDPVIDQNFYITVDHNLIIKQTRLADSANYTCVAKNLVAKRRSSTATITVYVNGGW
What is the function of this protein?
Receptor for netrin required for axon guidance.  Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity).
What are the official names of this protein?
Netrin receptor unc-5 homolog.
What is the protein family that this protein belongs to?
Belongs to the unc-5 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: BETB_CERS5
Sequence: MRAQPAASHFVDGRPLEDAAGAPIPVIHPANGEEIARLHEATPAVIEAALASGARAQKDWAALRPVERARILRRASDLIRARNEELSILETLDTGKPLQETLVADWPSGADALEFFAGLAPAVTGETVPLGQDFVYTIREPLGLCVGIGAWNYPSQIACWKAAPALALGNAMVFKPSEVTPLGALKLAEILIEAGLPPGLFNVVQGRGAVGAALVSDSRVAKVSLTGSVPTGRRVYAAAAEGVRHVTMELGGKSPLIVFDDADLESAIGAAMLGNFYSSGQICSNGTRVFVQKGIKEAFLARLAERADAIQMGDPLDPEVQMGPLVSPAQLEKVLSYIEKARAEGGRLVCGGEASVSPGCYVQPTVFADVTDGMTLAREEVFGPVMAVLDFETEEEVIARANATDFGLAAGVFTADLTRAHRVVAQLQAGTCWINAYNLTPVEAPFGGVKMSGVGRENGRAAVEHYTQVKSVYVGMGPVDAPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: KTHY_NEIMB
Sequence: MKPQFITLDGIDGAGKSTNLAVIKAWFERRGLPVLFTREPGGTPVGEALREILLNPETKAGLRAETLMMFAARMQHIEEVILPALSDGIHVVSDRFTDATFAYQGGGRGMPSEDIEILEHWVQGGLKPDLTLLLDVPLEVSMARIGQTREKDRFEQEQADFFMRVRGVYLDRAAACPERYAVIDSNRNLDEVRNSIEKVLDGHFGC
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CALM_ONCSP
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
What is the function of this protein?
Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding.  Calcium-binding is required for the activation of calmodulin.  Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: CH101_RHOPA
Sequence: MAKINFRPLHDRVVVKRIDAETKTKGGIIIPDSAKEKPQEGQVIAVGPGGRDETGKLTPIDVKVGDRVLFGKWSGTEIKLDGEELLIMKESDIMGVVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES 1, 10 kDa chaperonin 1, Chaperonin-10 1, Cpn10 1.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELU_NITEU
Sequence: MRNPDIGIDDLTALFIADTPLIDVRAPVEFTQGSLPGAVNLPILNDEERALVGTTYKQQGSEAAIKLGYEMVSGSVKQNRLQQWLDFIHQHPRAILYCFRGGKRSQITQQWLRDTGIDSPLITGGYKRARQFLISTIDRFSEHRKLLVITGPTGSGKTRLIHDISNSHPVLDIEALARHRGSAFGGMSVPQPSQIDFENHLAVNLLKLEQNNLSEPVIVEDESRHTGKVYLPDSFFHHLRNSEIIWVDEPLATRVDNIFEDYILTTPIGQAQRIRQAIPPLASTVETREILRQQARQLFDKYAGALQAISKKLGGDRFQEVSEDLENARSDFENKNEIQSNKIWIEKLVRYYYDPLYLGSLQRRRVNPCFKGSGQAVMDYLQARK
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: DEF4_PANTR
Sequence: MRIIAILAAILLVALQVRAGPLQARGDEAPGQEQRGPEDQDISISFAWDKSSALQVSGSTRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD
What is the function of this protein?
Host-defense peptide that has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi (By similarity).  Exhibits antimicrobial activity against Gram-negative E. coli and E. aerogenes and Gram-positive S. faecalis, S. aureus and B. cereus and the yeast C. albicans (in vitro) (By similarity).  Inhibits corticotropin (ACTH)-stimulated corticosterone production (in vitro) (By similarity).  Inhibits enzymatic activity of B. anthracis lef/anthrax lethal factor (in vitro) (By similarity).
What are the official names of this protein?
Defensin alpha 4, Corticostatin HP-4, HNP-4, HP-4, Neutrophil defensin 4.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Stored as mature peptide in neutrophil granules.
Protein: MENG_STAAE
Sequence: MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKLVHGDAMELPFEDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLPVFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKGD
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: ACPS_ALKMQ
Sequence: MIKGIGIDIIEIERIARALEKNPRFKERLFTLEENRGFIEKGGHPASIAGVFAAKEAVVKALGTGISNMKWKDIEVLKDSAGKPYIKLHNNALEIAYSKNINEIFISISHSKENAVAQAIAT
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_SYNC1
Sequence: MERTLAIIKPDAFAAGHAGGILARIYEEGFRVIGMKKLALSEKQAAGFYYVHEGKPFFDDLKGFMSSGPCVVMVLEADGAIRKWRDLMGATNPADAAAGTLRKEFGTSLGRNAVHGSDAPETAAFEVGYFFAGLDLL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAGP_CITRI
Sequence: MVVNVVIVAKKYFLFITLLIIQVSLPAHAGTDEKGWFNTFTDNVAETWREPEHYDLYIPAITWHARFAYDKRKTDRYNERPWGGGFGQSRWDEKGNWHGLYVMAFKDSWNKWEPIGGYGWESTWRPLPDDNFHLGLGFTAGVTARDNWKYIPVPVLLPLASIGYGPATFQMTYIPGTYNNGNVYFAWMRFQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PUR2_CAUVC
Sequence: MEKLTILLVGSGGREHALAWKIAQSPLCGRLVAAPGNPGIEAVAELRAVKATDADGLVALAQEIGADLVVVGPESALEVGLADKLAAVGIPCFGGSQRAAQLETSKAFTKDFCQRHGLPTAAYGVFEDAASAGAFLDTLEAPFVIKADGLAAGKGVVIAPDRAAADAAVVDMLGGRFGSAGARVVIEEFMHGEEASLFAVCDGKTAVLFGAAQDHKRAYDGDEGPNTGGMGTYSPPPVLTDALIDQAWRELIVPTVEGMAAEGNPYVGVLYAGLMLTPTGPKLVEYNARFGDPECQTLMLRLDSDIVPILLAAAKGELANAEPPKWREEAAICVVLAAEGYPDAPKTGGRIQGADADFGDDVVVFHAGTTREFEGRLVASGGRVLNVCALGATLSEAREAAYGALETISLEGGFYRTDIGWRALQQR
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: VF62_ASFWA
Sequence: MNRGSISSGTPGLFVGSMRNTPFVVKINVIFLKVISNTAVSVFWRDRRIRFESDWLNSYFQK
What are the official names of this protein?
Uncharacterized protein C62L, pC62L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C62L family.