PharMolix/UniProtQA huggingface dataset:
Protein: RL15_CLOPE
Sequence: MKLHELRPAAGSKSAPKRVGRGTGSGLGRNAGKGEKGQNARSGGGVRPGFEGGQMPLYRRLPKRGFTNPFTKHFVTINVDRLNIFDNGTEVTPELLLERRVVSKLMDGVKILGNGNIEKSLTIAGCKLSKQAAEKIVAAGGKVEVK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ATPB_MYCLE
Sequence: MSTTKTTKMTVKTGSKGTSGRVVRVTGPVVDVEFPHGFVPELFNALNAKTTFSSLAKTLTLEVAQHLGDNLVRTISLQPTDGLVRGVEVTDTGNSISVPVGEGVKGHVFNALGYCLDEPGYGDEFEHWSIHRKPPSFEELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELQEVNVLKDTALVFGQMDEPPGTRMRVALSALTMAEWFRDEASQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRSVFAKGIFPAVDPLASSSTILDPGIVGEEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPVKETIDAFDRLCKGEFDHVPEQAFFLIGGLDDLTKKAESLGAKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y7957_DICDI
Sequence: MTFIIKKVKNIFSTKKINNKTNNNNFKNENLNIKNEILNNNNNNNNNKNNNNNNNNNNNIENNSKNENFNNFNKIHNSPISSPNLSPSLNSIDSINLNKIIIQNIDNFETNGNILNTSSPSLNSSVAKNNFIISDIQDIDWNNLVNIELLNNNINNNNNTNNNNNNNIIILVTFYNGYDDFNQVILKSSNTMVQDVYASVLQVILKYPVPEMRLIDSCEEEFNKMSINLLKQSKLQSEQLFNIIQTQIEKPFFLIMEYKNGGKFFSQLNHKEYFSSQKNGEKKLKQLGKLLSFDLICNINNNICNFNYNNCNNNNNNNNNNNNNNNNNNNNNNNNNNINNCNNNNNNNISLNNSNNNLNSIFNNNNFNIFSNIIFYEQPDKNGWYFGIIHSSILCLNSSSFTPGYRNTMDRIKLLLFSIFQNPTTESLQIYHFRKYLSNNCNINLPSSSVHWSTNIQNGIAKGIDELVNSLNYQVFASTKQIVNNMIFSTTDQNNNNVIINNNNSFTWKKGIDLIYIPFLFDVLKEIIIEHSNYKNKSKK
What are the official names of this protein?
Putative actin-fragmin kinase DDB_G0287957.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AFK Ser/Thr protein kinase family.
Protein: OTC_CAMJ8
Sequence: MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPVKDTARVIGTMVDFVMMRVNKHETLLEFARYSKAPVINALSEFYHPTQVLGDLLTIKEWNKMQNGIAKVAFIGDSNNMCNSWLIVAAILGFEFSIAIPKNYKISPEIWEFAMKQALISGAKISLSHDKFEALKDKDVVITDTWVSMGEENEKERKIKEFEGFMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRE
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_ECODH
Sequence: MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TRPD_GEOSL
Sequence: MIKKAIAKVVERIDLTEAEMIEVMDQIMSGGATPAQIAAFITALRMKGETVEEITGAARVMRDRATPIRVGKGVLDIDRDDINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKVAKHGNRAVSSACGSADVLESLGVNLDVTPETVEQAIAKIGIGFLFAPALHGAMKHAIGPRKEIGIRTIFNILGPLTNPAGADCQVLGVYREELVEPLARVLHKLGCRRGFVVHGMDGMDEITLTRETRIAEVTRDGVSVRTITPEEFGFASCPAGELRGGDAAGNARIVRGILEGATGPRRDVVLLNAAFGLVAAGKAVDPAEGVRIAAEAIDSGRALAKLEELITLTNE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CD2B2_HUMAN
Sequence: MPKRKVTFQGVGDEEDEDEIIVPKKKLVDPVAGSGGPGSRFKGKHSLDSDEEEDDDDGGSSKYDILASEDVEGQEAATLPSEGGVRITPFNLQEEMEEGHFDADGNYFLNRDAQIRDSWLDNIDWVKIRERPPGQRQASDSEEEDSLGQTSMSAQALLEGLLELLLPRETVAGALRRLGARGGGKGRKGPGQPSSPQRLDRLSGLADQMVARGNLGVYQETRERLAMRLKGLGCQTLGPHNPTPPPSLDMFAEELAEEELETPTPTQRGEAESRGDGLVDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFDLYT
What is the function of this protein?
Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.
What are the official names of this protein?
CD2 antigen cytoplasmic tail-binding protein 2, CD2 cytoplasmic domain-binding protein 2, CD2 tail-binding protein 2, U5 snRNP 52K protein, U5-52K.
Protein: DEOC_EXIS2
Sequence: MNLAGMIDHTALKAETSRAQIETLCKEALEYKFASVCVNPTNVALAAELLKSDDAVKVCTVIGFPLGANTPEVKAFETQDAIKNGATEIDMVLNIGALKDGDLSLVERDIRAVVEAANGTLVKVIFENCLLTKEEIKTAAELSVKAGADFVKTSTGFSTGGATVEDIRLMRETVGPDIGVKASGGVRDFEGAKAMIDAGATRIGASAGIAIVTGGTSDSDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_CLOPS
Sequence: MDKKKYIRNFSIVAHIDHGKSTLADRLLEKTGTLTQREMEQQVLDTMELEKERGITIKSQAARLIYKRENGEEYILNLIDTPGHVDFTYEVSRSLAACEGAILVVDATQGIQAQTLANCYLALDNDLEIVPVINKVDLASARPDEIKQEIEDVIGIEAEDAPLVSAKTGLNIEDVLEEIVEKIPAPEGDENAPLKALIFDSYYDSYKGVVCHIRVKDGKVKPGTKIKLMSTDKVYEVVETGVFTPALMPLKEGLSAGEVGYITASIKNVRDARVGDTVTEAARPTEEALPGYKPAIPMVYSGIYPVDGAKYEELKEALEKLQINDAALSFEPETSVALGFGFRCGFLGLLHMEIIQERVEREFNLDIITTAPSVIYKVTKTNGESFDLTNPTNLPPMTEIAYMEEPVVKASIITPTDYTGAVMELCQDRRGKFIDMQYLEETRVVIHYEIPLNEIVYDFFDTLKSKTRGYASLDYELKGYEQSKLVKLDILLNGDNVDALSMIVPEVKAYQRGRAIAEKLKEIIPRHMFEVPIQAAVGSKIIARETVKAMRKDVLAKCYGGDISRKKKLLEKQKEGKKRMRQLGTVEVPQEAFMSVLKVD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FETP_BURM1
Sequence: MARMIQCAKLGKEAEGLDFPPLPGELGKRIYENVSKEAWQGWLKQQTMLINENRLNMADPRARQYLMKQTEKYFFGEGADQASGYVPPTEG
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RL13_HISS2
Sequence: MKTFVAKPETVKRDWYVVDATGKTLGRLAAELARRLRGKHKAEYTPHVDTGDYIVVINAEKVAVTGNKETDKLYYWHTGYVGGIKQATFKEMIARRPEAVIEIAVKGMLPKGPLGRAMFRKLKVYAGSEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: KPTA_ECO24
Sequence: MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLILCAQKAGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQFLYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKRGLPFWQAENGVWLTSTVAVEFLEW
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: PNO1_MOUSE
Sequence: METQSTGTEDGFTPVTHRGGRRAKKRQAEQSSAAGQDGEAGRMDTEEARPAKRPVFPPLSGDQLLTGKEETRKIPVPGNRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVHVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
What are the official names of this protein?
RNA-binding protein PNO1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y2332_RHIEC
Sequence: MSKPPSDLPRRPPAAFAYEDEAAEPGDNGRQQQGRRRPESFSEDIVLTPDEEDPFINPDRDPSAVAVATPRKRRTSFGKIALAAFGILLSLGIGLWTDRLIRDLFSRADWLGYAALGVLAIGILAVLALVIREAAGMMRLAAVQTIKAEAEAAILETRPAKARAVVSRLTTLLAANPETSKGRATLKATEGEVIDPPHLIALAERELLAPLDRKARALIVNASKRVSIVTAVSPRAIVDLLYVLYESVRLIRAMAELYGGRPGTLGMFRLLRDVLAHLAVTGSIAVGDSLVQQVLGHGLASKLSARLGEGVINGLMTARIGIAAMDLCRPLAFRAVKRPGIGDFIGDLTPSMSPRGNNP
What are the official names of this protein?
UPF0283 membrane protein RHE_CH02332.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GDL54_ARATH
Sequence: MAISKITLAIIVLLLGFTEKLSALSSSCNFPAVFNFGDSNSDTGAISAAIGEVPPPNGVAFFGRSAGRHSDGRLIIDFITENLTLPYLTPYLDSVGANYRHGANFATGGSCIRPTLACFSPFHLGTQVSQFIHFKTRTLSLYNQTNGKFNRLSHTNYFSKALYTLDIGQNDLAIGFQNMTEEQLKATIPLIIENFTIALKLLYKEGARFFSIHNTGPTGCLPYLLKAFPAIPRDPYGCLKPLNNVAIEFNKQLKNKITQLKKELPSSFFTYVDVYSAKYNLITKAKALGFIDPFDYCCVGAIGRGMGCGKTIFLNGTELYSSSCQNRKNFISWDGIHYTETANMLVANRILDGSISDPPLPTQKACKLTKK
What are the official names of this protein?
GDSL esterase/lipase At3g27950, Extracellular lipase At3g27950.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOB_NAUPA
Sequence: MKKIYLCAISNIRSGACNEDCKFCTQSVKWGADINRYKQKDLKTIVNEAKLAKKNGATGFCLVTSGKGLDDKTLEYVCSAAKSVIKEVDISIIACNGTAGKDSLKELKKAGVKIYNHNLETSREYYPKICSTHTWDERFETCENIKSVGLQLCCGGIFGMGESNEDIESFIRSLKELKPNGIPLNFFIENEKLPLKATHNKDFALKTVKRFANEFKEAIIMLAGGREIVFGNEWTEALKVGANSIVIGDYLTTKGERPDRDLEILLNEGFEIANEC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ALR_CAMJ8
Sequence: MSLIKIDQKAYEYNLRHIAKKIGSFQRLICVFKDNAYGHGAKLLAPLAKNLGVSFVAVKSEEEAQEIEEFFENILILSHRPHGNENSRFIYALNDISQVKKYKQDIKIHLKIDTGMHRNGICVENLEHAIDLIRSSDLKLTGMFTHFASADEMDGSFFVQKENFQKAKKIVKKYFSNLLFHSHNSAALFRGKIPEDEYCRVGLVQFGYGDSNLKRVLSLYAHRLSQRILQKGQSIGYGGIFTAAKDMEVATYDLGYADGLFRYNGKGELVLGNGKVMLGKMSMDSFSCENSGEEICVFKDADIWADFFHTINYEILVKLNPNIQRVLV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: HYPA_GEOUR
Sequence: MHEMSITQSVVEICTQNAGGRRVTAVILEIGDLSGVVPDAIEFCFEACTRDTQLDGARLLIERVQALGRCRDCKAEFALSAYYDPCPACGGFGVDVLSGEELRVKELEVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: RELJ_MYCTU
Sequence: MSISASEARQRLFPLIEQVNTDHQPVRITSRAGDAVLMSADDYDAWQETVYLLRSPENARRLMEAVARDKAGHSAFTKSVDELREMAGGEE
What is the function of this protein?
Binds to and represses its own promoter, in combination with RelK repression is somewhat lessened.  Several DNA-protein complexes are formed in vitro depending on the RelJ:RelK ratio.
What are the official names of this protein?
Antitoxin RelJ, Antitoxin YefM.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: ISCR_YERPE
Sequence: MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINVNLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: LEU3_JANSC
Sequence: MTDRSLLILPGDGIGPEVMAEVRKIIDWFGSARGISFDVSEDLVGGAAYDAHGVPLTDATMEKAQSVDAVLLGAVGGPAYDDLDFSVKPERGLLRLRKEMDLYANLRPAQCFDALADFSSLKREIVSGLDIMILRELTSGVYFGEPRGIHTEGNERVGINTQRYTETEIARAAHSAFELARRRNNKVCSMEKANVMESGILWRDVVNEVHAADYGDVQLSHMYADNGAMQLVRAPKQFDVILTDNLFGDILSDCAAMLTGSLGMLPSASLGAPMANGRPKAMYEPVHGSAPDITGQGKANPIACILSFAMALRYSFDLGDEATRLEGAVESVLADGARTADLMGPDGGTPISTSQMGDAIVAKLAA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRYB2_MOUSE
Sequence: MLKRRLLLLWALSLLASLVYSAPRPANQRVGIVGGHEASESKWPWQVSLRFKLNYWIHFCGGSLIHPQWVLTAAHCVGPHIKSPQLFRVQLREQYLYYGDQLLSLNRIVVHPHYYTAEGGADVALLELEVPVNVSTHIHPISLPPASETFPPGTSCWVTGWGDIDNDEPLPPPYPLKQVKVPIVENSLCDRKYHTGLYTGDDFPIVHDGMLCAGNTRRDSCQGDSGGPLVCKVKGTWLQAGVVSWGEGCAQPNKPGIYTRVTYYLDWIHRYVPEHS
What is the function of this protein?
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.  Plays a role in innate immunity.
What are the official names of this protein?
Tryptase beta-2, Tryptase-2, Mast cell protease 6, mMCP-6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Tryptase subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Released from the secretory granules upon mast cell activation.
Protein: TBB_ASPOR
Sequence: MREIVHLQTGQCGNQIGAAFWQTISGEHGLDGSGVYNGSSDLQLERMNVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVVDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICMRTLKLSNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVSMKEVEDQMRNIQSKNQTYFVEWIPNNIQTALCSIPPRGLKMSSTFIGNSTSIQELFKRVGDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASISEGEEEYLEEEEPLEHEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MOM2_CAEEL
Sequence: MHINTPVLLAIIYFLVFAPKSADAWWLLSKTDTSSANSGSSPILCKNVPGLTPQQKRMCHENPNIIKYLISGLRSALHTCEYTFQREAWNCTLTLPGVGTSPLQIASRESAYVYAISAAGVSHSLARACSKGLIDDCGCGETPQGSGSVAVSQASSRSSSDFVWAGCSDNVKFGNTFGRKFVDQYDRQHATEPRSQMNLHNNRVGRRLLVNAMNKECKCHGVSGSCVTKTCWKVMPKFDEFASRLHQKYQLAKLVTNNDQKLTVRSSPSAGSSGRSERFARNMDASSKQMRNELIYLDASPNYCAIDVKDRECGENCPNICCGRGWRTTREIVDEPCHCQFVWCCEVKCKTCKKLVERNYCL
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Required in embryonic development for endoderm specification and the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells (PubMed:9288750, PubMed:9288749, PubMed:16678095, PubMed:25344071).  Involved in cleavage axis determination (PubMed:9288750).  Binds to receptor tyrosine kinase cam-1 (PubMed:17942487).  Together with wnt ligand lin-44, plays a role in controlling vulva precursor cell P7. p lineage orientation during vulva development, probably by acting as a ligand for tyrosine kinase receptor lin-18 (PubMed:15369677).  May act redundantly with other Wnt ligands such as cwn-1 and cwn-2 to control seam cell polarity (PubMed:22022276).
What are the official names of this protein?
Protein mom-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: FMT_ECOBW
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVAELQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RBL_MOROL
Sequence: SVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPIAGEENQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGAPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIFFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIRKASKWSPELAAACEVWKEIKFEFPAVDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUB4A_COCP7
Sequence: MVSMKFLSTVFAAITAANAAEILSVPNTQDVIPDSYIVVMKDEVATSDLEAHVTWVRNHHHSGHVRRNGTLTGLKTTFDISGFRGYLGAFDHDTLDEILADDKVKFVEPNRIMRIQGTQTQRGAPWGLARLSSSRPGGSDYVYDDRAGEGVIIYGVDTGIDVNHPDFEGRATWGINTIDQDNTDGNGHGTHTAGTFAGARFGVAKKATIVGVKVLDAQGSGSNSAIMEGISWSVDHARKNNALGRAVMNLSLGGSFSQAVNDAAERAVRAGVFLAVAAGNDNQDASNYSPASAPNVCTVGATDRMDVRATFSNFGSVLDIFAPGVDVESTMPGGGTQMMSGTSMAAPHIAGLGAYLMSTENLQPSQVCDRIKQLASNSVRNPGNGSTSKLANNGIGQ
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease CPC735_066880.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14_RALPJ
Sequence: MAKLSLIEREKKRAKLVAKYAEKRAALEAIVADQSKSEEERYEARLKLQALPRNANPTRQRNRCSITGRPRGTFRKFGLARNKLREIAFKGEIPGLTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: OBG_PSECP
Sequence: MASFVDRVVLHVSGGTGGHGCVSVHREKFKPLGGPDGGNGGNGGDVILRVDHQTTTLLDYHHAPHRHATNGGPGMGDWRGGKNGETLVLPVPDGTVVKSKDGTVLADLVGEGTEYIAAAGGPGGLGNAALSSQKRRAPGFALLGIEGESSDIVLELKSIADIALVGFPSAGKSSLIAAMSAARPKIADYPFTTLIPNLGVVQAGDVRFTIADVPGLIEGASEGKGLGHNFLRHVERCAALVHVLDCGTLESDRDPLSDLSIIETELEKYAVDMSYAGQDGEVVPLNHRPRLVALNKVDLPDGKDMAEFVRPELESRGYRVFEVSATSHEGLRQLGFAMAEIVKAARDAVEAAPPKVTPTVLRPRAVNETGFRIRREEKAHEPLFRVLGDKPVRWVKQTDFTNEEAIGYLADRLARLGVETELFKMGAKPGDTVVIGEDDGVVFDWEPTMMAGAELLASPRGTDIRFADTGDRPTRSQKREEQQERRDAKAAARAELEAERKAGIWTESVSGRRAAQPIKESGLDSGDES
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXD_ECOLI
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTLVQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGTVFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQVIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGAGWQWVNLAWLAGGVWLLWQKAIRWHIPLSFLVTLALCAMLGWLFSPETLAAPQIHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity).  Required to maintain the reduced state of SoxR.  Probably transfers electron from NAD(P)H to SoxR (PubMed:12773378).
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.