PharMolix/UniProtQA huggingface dataset:
Protein: DDL_STAAE
Sequence: MTKENICIVFGGKSAEHEVSILTAQNVLNAIDKDKYHVDIIYITNDGDWRKQNNITAEIKSTDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLWENMGLSYPELITKLIELAKERHQDKQKNKYKID
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTM1A_HUMAN
Sequence: MTSEVIEDEKQFYSKAKTYWKQIPPTVDGMLGGYGHISSIDINSSRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFREVDMVDITEDFLVQAKTYLGEEGKRVRNYFCCGLQDFTPEPDSYDVIWIQWVIGHLTDQHLAEFLRRCKGSLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLDVVRRIICSAGLSLLAEERQENLPDEIYHVYSFALR
What is the function of this protein?
Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved.  Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif.  Some of the substrates may be primed by NTMT2-mediated monomethylation (PubMed:24090352).  Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1).  Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET.  Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
What are the official names of this protein?
N-terminal Xaa-Pro-Lys N-methyltransferase 1, Alpha N-terminal protein methyltransferase 1A, Methyltransferase-like protein 11A, N-terminal RCC1 methyltransferase, X-Pro-Lys N-terminal protein methyltransferase 1A, NTM1A.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. NTM1 family.
What are the subcellular locations of this protein?
Nucleus. Note=Predominantly nuclear (PubMed:24090352).
Protein: METAA_GEOSW
Sequence: MPINIPKDLPAKEILEQENIFVMDEERAYSQDIRPLNIVILNLMPEKEKAETQLLRLLGNSPLQVNVTFLRPATHESKTTSKHHLEQFYTIFPHIRHRKFDGMIITGAPVEQMPFEKVTYWSELTEIMEWTKTNVTSTLHICWGAQAGLYYHYGIPKYPLPQKCFGIFEHSLEVKNVKLLRGFDDVFRMPHSRHTDVKREDIEKIPELTILSVSEKAGVCLVASNDGKQIFLTGHPEYDATTLKEEYERDLAKGLPIHIPESYFPNDDPTKEPLNTWRSHANLLFVNWLNYYVYQETPYEWE
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1401_STRP4
Sequence: MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAVRHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS
What are the official names of this protein?
UPF0291 protein SPG_1401.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SV2C_MOUSE
Sequence: MEDSYKDRTSLMKGAKDIAKEVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEDDDDYYPPGETYSGEVNDDEGSSEATEGHDEEDEIYEGEYQGIPSTNQGKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLVCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSDEYALLTRNVQKDKYANFSINFTMENQIHTGMEYENGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFDNTDFEPYKFIDSEFQNCSFLHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM
What is the function of this protein?
(Microbial infection) Possible receptor for C. botulinum neurotoxin type D (BoNT/D, botD) (PubMed:21483489).
What are the official names of this protein?
Synaptic vesicle glycoprotein 2C, Synaptic vesicle protein 2C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.
Protein: MTND_BACAN
Sequence: MAQIRIHEVNTRIENEVKVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSARRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: KPTA_METMA
Sequence: MIRKCTDHGYFRGGSCQQCKRPGRYVLDDGREEKLGRFVSGTLRHFPASAGVKMDKYGWIDLNAFCEVMKKRYNWMRKEYLYALVESDEKGRYQISGPMIRARYGHSVNVDLDYDESDTPYVYYGASPEEVDVLLENGIFPIKQRYVHLSTTYEKAAEVALIHTESPVILQVDAFRAQEDGISLKLATDYIVLAEKIPPDYLFVLED
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: MSPD1_HUMAN
Sequence: MHQQKRQPELVEGNLPVFVFPTELIFYADDQSTHKQVLTLYNPYEFALKFKVLCTTPNKYVVVDAAGAVKPQCCVDIVIRHRDVRSCHYGVIDKFRLQVSEQSQRKALGRKEVVATLLPSAKEQQKEEEEKRLKEHLTESLFFEQSFQPENRAVSSGPSLLTVFLGVVCIAALMLPTLGDVESLVPLYLHLSVNQKLVAAYILGLITMAILRT
What is the function of this protein?
Plays a role in differentiation and/or proliferation of mesenchymal stem cells.  Proposed to be involved in epithelial-to-mesenchymal transition (EMT).  However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.
What are the official names of this protein?
Motile sperm domain-containing protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: A1AT2_HORSE
Sequence: MPSSVPWCLLLLAGLCCLVPSSLAEDLQGCAVQETHATAHDEEHLQEPAEHKIAPNLADFAFSLYRHVAHQSNTTNIFFSPVSIATAFALLSLGAKGDTHTQILEGLSFNLTELAEAQIHDGFQHLLNALNHSDNQLQLTTGNGLFIDESAKLLDKFLEDVKKLYHSEAFSINFRDTEEAKKQINDYVEKGTQGKIVDLVKDLDKDTVLALVNYIFFKGTWEKPFEPEYTTEQDFHVDEKTTVRVPMMHRLSSFDVQYSDTLSSWVLLLDYAGNATAFFILPDQGKLQHLEDTLTKGILARFLGNRHSSFVNVHLPKLSISGTYDLTSILPELGITKVFSRQADLSGITEEVPLTVSKALHKAVLTIDEKGTEAAGTTMWEIMPISLPPDLKFNRPFVLIIYDRNTKSPLFVGKVVDPTQK
What is the function of this protein?
Inhibitor of serine proteases.
What are the official names of this protein?
Alpha-1-antiproteinase 2, Alpha-1-antitrypsin 2, Alpha-1-proteinase inhibitor 2, SPI2.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFG_THESQ
Sequence: MENVEARYVDLDKLRNIGIMAHIDAGKTTTTERILYYTGRKHFLGDVDEGNTTTDWMPQEKERGITIQSAATTCFWKGYRINIIDTPGHVDFTAEVERALRVLDGAIAVFDATAGVEPQSETVWRQADKYNVPRIAFMNKMDKVGADFYMAVETLVTKLKANPIPVQMPIGSEKDFQGVIDLIKMKAIYWVSEDGSVYEERDIPEELREEAEMRREEMLEKVAELDEEILEKYLEGEEISEEEIKRILRKATIENRAVPVLCGAAKANKGIQPLLDAVIDYLPSPLDLPPVKGWRVSDGEIVYRKPDENEPFTALVFKVQVDPYIGKLVYFRVYSGRLEKGSYVYNSTKGQRERISRIVFMHADKREEVDYVRPGDIAAGVGLKVSQTGDTLCDEKEPVILEKIDFPEPVISLAIEPATKADEEKLVKALLALSEEDPTLQVRVDKETGETIISGMGELHLEIVVDRLKREFGVNVRVGQPQVAYRETIKRPAEAEGKYIRQTGGRGQYGHVILRIEPIPEEEGKNFEFIDKTVGGVIPKEFMPAIEAGIKEAMMSGPLAGYPVVRVRAVVLDGSYHEVDSSEMAFKIAASMAFKEAMKKAQPVLLEPIMKLEITTPEEYMGNIISDLNSRRAKIESLETRGHLKIVVAKIPLSETFGYATVLRSLSQGRASYIMQFSHYQEVPEKIAEKIIKVV
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_PROM3
Sequence: MSPLPPSAEACRDELLNRLAREAYRHGDFTLASGRQSNHYVNCKPVSLSGSGLELLGLALLKYVEPDAVCVAGLTLGADPLVSAVAMAAAQAERTLNALIVRKQAKGHGTAAWLEGPLPPSGARITVLEDVVTTGGSSLKAVQQLRETGYLVTRVVTIVDRQEGGEEALNAAELELVSLYQLNQVAERARQLETET
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RPOA_YERE8
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASARIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: HIS8_RHOPA
Sequence: MSRPVPNPGILDIAPYTPGKSPVAEPGRKVFKLSANETPFGPSPHAIAAYKSAADHLEDYPEGTSRILREAIGKAYGLDPDRIICGAGSDEILNLLAHTYLAPGDEAISSQHGFLVYPIATLANGAKNVVAPEKNLTTDVDAMLAAVTPNTKLVWLANPNNPTGTYIPFDEVKRLRAGLPSHVVLVLDAAYADYVMKNDYELGIELVSTTENTVLTHTFSKVHGLAALRIGWMFGPANIVDAVNRIRGPFNVSVPAQLAAVAAIQDTGHVERSRAHTDKWRNTLAEELPKLGLTVTRSVCNFVLIHFPTTKGKTAAEADAFLTQRGLVLRALNNYGLPHALRMTIGTDEANALVLENLREFMGQP
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ACCD_AERS4
Sequence: MSWLEKILPKSKITTPRRHNIPEGVWTKCSACEQVLYRAELERNLEVCPKCDHHMRISARARLESFLDEQGRTEVGAELEPQDILKFKDSKRYKDRLSAAQKATGEKDALVVMKGTLKGVPVVACSFEFSFIGGSMSSVVGARFVRAVEECIKEGRGLVCFSASGGARMQEALFSLMQMAKTSAALDRLTKAGLPYISVLTDPTMGGVSASLAMLGDINVGEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLEKGAIDLIIDRREMRNRLASLLAKMLNTHVIEE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_STAAU
Sequence: MSHLALKDLFSGFFVIDDEEEVEVPDKQQQVNEAPAKEQSQQTTKQNAIKSVPQKSASRYTTTSEERNNRMSNYSKNNSRNVVTMNNATPNNASQESSKMCLFEPRVFSDTQDIADELKNRRATLVNLQRIDKVSAKRIIDFLSGTVYAIGGDIQRVGTDIFLCTPDNVEVAGSITDHIENMEHSFD
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RSMC_IDILO
Sequence: MSAAILSMLGRQSAQPWANGSLLVIHPGGGELSALPNASAWSFHAGHAAYWKAAGRPVFCQIQPPNLSHYDGVLFLVAKEKELNQYLLEQLASLPTGTPVWFAGEKRSGIQPLMKHLPAWLQPPQKLASANHCLLFASERNEQVHQSASIEDYAKNITYELNQQQESFVTLPGVFSREHIDPATLLLLQHIKDLPKGRGMDFACGAGVIAKQLASVATELMACDVSPIAIAASEITLANEPVKTELRLADGIPDNAGQFDFIVSNPPFHTGQRTDYEIAREFISNARQHLNKQGVFRVVANRFLPWPEVIESVFGNCSVIADDGRYRVYHATCR
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC9_MESAU
Sequence: MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITINQLFIGIQELLNEPNIQEPAQAEAYTIYCQNRVEYEKRFRAQAKKFCPS
What is the function of this protein?
Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451 (By similarity).  Can catalyze the formation of poly-SUMO chains (By similarity).  Essential for nuclear architecture and chromosome segregation (By similarity).  Necessary for sumoylation of FOXL2 and KAT5 (By similarity).  Sumoylates p53/TP53 at 'Lys-386' (By similarity).  Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity (By similarity).
What are the official names of this protein?
SUMO-conjugating enzyme UBC9, RING-type E3 SUMO transferase UBC9, SUMO-protein ligase, Ubiquitin carrier protein 9, Ubiquitin carrier protein I, Ubiquitin-conjugating enzyme E2 I, Ubiquitin-protein ligase I.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear (By similarity). In spermatocytes, localizes in synaptonemal complexes (By similarity). Recruited by BCL11A into the nuclear body (By similarity).
Protein: KCY_THEAC
Sequence: MRITIAGKIGSGKSTVSSELSRITGYTVYSSGTFFRETARKMNMSIEDFNVYSESHPEADYYTDETQKAFMQANDNIIVEGRLAGWISYLNGINAFRIFLYATYYTRLVRFAGRENIDIDSARDLMEKREKSEKERYRKLYGIDVDDLSIYDIVVNTEFMKPPEIAVYIANRIDEMSRKDIFTPRILR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_GEOKA
Sequence: MKLLTLLSHLPGFWVHHGGNPDIVALEMDSRRVASGSLFFCLKGFTVDGHDFAEEAVARGAAAIVAERPLSVDVPVVLVSDSRRAMAILADAFYGRPTHRLHLIGVTGTNGKTTTTSIIEQIARKTGKKTGLIGTVHIKVGDRSYPAANTTPESLILQRTFKQMVDEGVEFVAMEVSSHALHQGRVHGCDYDVAVFTNLTQDHLDYHGTMEEYRNAKGLLFAQLGNRYDERRPKFAVLNHDDPVSQYYKHMTAAPIVTYGMREKSDVMAEQIRMTAGGMAFRLCTPHGSAAVETKLVGSFNVYNILAAAAACLASGFSLETIAAALADVEPVPGRFETVDEGQNFTIIVDYAHTPDSLENALKTVRQLAKRNVYVVIGCGGDRDPSKRPLMAQVAVRYADVAIFTSDNPRSEDPKQILRDMEAGVSAEIGKHVTIPDREEAIRYAIGQAQEGDVVLIAGKGHETYQIIGNDVIEFDDRAVARAAVKERG
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS2_LISIN
Sequence: MTGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNANVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAVPLIGDYLIEKYGEEDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGDATERLQNSRIKEVITSDSIDLPEEKQFEKLTTISIGRILGRAIEGVQENRSLHPLF
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Putative ribose-phosphate pyrophosphokinase 2, RPPK 2, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 2, Phosphoribosyl diphosphate synthase 2, Phosphoribosyl pyrophosphate synthase 2, P-Rib-PP synthase 2, PRPP synthase 2, PRPPase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP24_MOUSE
Sequence: MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGPSPGPGGGPRGDSGSDGSGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMERCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERMKQDPIPIGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAISPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPALVTTVDALRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNADQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFEATSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAVKRSYIIKCIEDIKRPGEWSSLEKNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLLACHRLAAAVAGPGGLTGLTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELVGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSSSSSGAFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTSLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEASDFTATVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRSRLSSSGSNCSSSSEGEPAALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLASFYSLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPEVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMDQLRISPATMLEDEITWLDNFEPNRTADCETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIIVNSHSPASSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSLDACQWLVEYFISSEGRELVKVFLLECSVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGVSRQNSQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISVAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEVLVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP
What is the function of this protein?
Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains.  Deubiquitinates DDB2, preventing its proteasomal degradation (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 24, Deubiquitinating enzyme 24, Ubiquitin thioesterase 24, Ubiquitin-specific-processing protease 24.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: CENPI_YEAST
Sequence: MSLILDDIILSLTNANERTPPQALKTTLSLLYEKSKQYGLSSPQLQALVRLLCETSIIDTVTKVYIVENCFLPDGYLTKELLLEIINHLGTPTVFSRYRIQTPPVLQSALCKWLVHVYFLFPVHSEREHNISSSIWLHLWQFSFLQKWITPLVIWQATTPVDVKPWKLSIIKRCAMHPGYRDAPGSATLILQRFQCLVGASSQITESIITINCNRKTLKSHRNLKLDAHFLSILKRILSRAHPANFPADTVQNTIDMYLSEIHQLGADSIYPLRLQSLPEYVPSDSTVSLWDVTSLEQLAQNWPQLHIPNDVDYMMKPSLNSNVLLPRKVMSRDSLKHLYSSIILIKNSRDESSSPYEWCIWQLKRCFAHQIETPQEVIPIIISVSSMDNKLSSRIIQTFCNLKYLKLDELTLKKVCGGILPLWKPELISGTREFFVKFMASIFMWSTRDGHDNNCTFSETCFYVLQMITNWVLDDKLIALGLTLLHDMQSLLTLDKIFNNATSNRFSTMAFISSLDILTQLSKQTKSDYAIQYLIVGPDIMNKVFSSDDPLLLSAACRYLVATKNKLMQYPSTNKFVRMQNQYIMDLTNYLYRNKVLSSKSLFGVSPDFFKQILENLYIPTADFKNAKFFTITGIPALSYICIIILRRLETAENTKIKFTSGIINEETFNNFFRVHHDEIGQHGWIKGVNNIHDLRVKILMHLSNTANPYRDIAAFLFTYLKSLSKYSVQNS
What is the function of this protein?
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis.  Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
What are the official names of this protein?
Inner kinetochore subunit CTF3, CENP-I homolog, Chromosome loss protein 3, Chromosome transmission fidelity protein 3, Constitutive centromere-associated network protein CTF3.
What is the protein family that this protein belongs to?
Belongs to the CENP-I/CTF3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: PANB_VIBC3
Sequence: MKKITINDLMKWKQEGRKFATSTAYDASFAQLFESQEMPVLLVGDSLGMVLQGETDTLPVTVDDIAYHTRCVRKGSPNCLLMADMPFMSYATPEQACENAAKLVRAGANMVKIEGGDWLVDTVKMLTERAVPVCAHLGLTPQSVNIFGGYKVQGREQDKADRMVRDALALQEAGAQIVLLECVPAELANRITQILDVPVIGIGAGNGTDGQILVMHDMFGISANYMPKFSKNFLAETGDIRQAVAKYIEDVASGAFPDLAHTIA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.