PharMolix/UniProtQA huggingface dataset:
Protein: PDXT_BACC2
Sequence: MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYAFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYEEAHIGAMDITVERNAFGRQKDSFEAALSIEGVGEDFVGVFIRAPYVVEVADNVEVLSKHGDRMVAVRQDQFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SCC4_DROSI
Sequence: MSASTSTSTAASQDACYISLLGLAEYFRTSQPPNIKKCIQCLQALFTFMPPSKVEARTHLQMGQILMAYTKNIDLARQHLEKAWSISEPLPNFDVKFDTASLLAQLHLQTDRNSHQAKAMLRRAVELSQNNVYWHCKLLLQLSQIHASDREYSLASELLAVGAESADEASATYLKVLFLLSRAMILMIERKTNDVLALLNSAGQIIDNNIPNPHQKEYLKVFFLVLQVCYYLALGQVKTVKPSLKQLQMSIQTIMAPNWPSDETIFGANQLEMFVWLPKEQLYVLVYLVTVSHSMMAGYMDKAQKYTEKALTQIEKLKQQEDKPILSVFKVILLEHIVMCRMVMGNRELAIREIAAARDVCMAAPQRSLLRRHSAQLHCLIGLYSMSTNLFEHAERQFVVCVSETSERDLKLFANLNLAIIYLRTKRDTDLKQILDAVSTENTHTYSSQALMGGFYYVQGLHAFHKNSFHEAKRFLRETLKMANAEDLNRLTSCSLVLLSHVFLSIGNSKESMNMVTPAMQLASKIPDIHVQLWGSAILKDLHRMSKDVQHEKDAYANHVKYSENLIADQRKCVQSAHHELVNWFQGDPPVTSGPPAAPVLLMPESSVTASVPVIASTSAAMQPAGQYGQFY
What is the function of this protein?
Required for association of the cohesin complex with chromatin during interphase.  Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity).
What are the official names of this protein?
MAU2 chromatid cohesion factor homolog, Cohesin loading complex subunit SCC4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC4/mau-2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Binds to chromatin from the end of mitosis until prophase.
Protein: DNBI_HHV1K
Sequence: METKPKTATTIKVPPGPLGYVYARACPSEGIELLALLSARSGDADVAVAPLVVGLTVESGFEANVAVVVGSRTTGLGGTAVSLKLTPSHYSSSVYVFHGGRHLDPSTQAPNLTRLCERARRHFGFSDYTPRPGDLKHETTGEALCERLGLDPDRALLYLVVTEGFKEAVCINNTFLHLGGSDKVTIGGAEVHRIPVYPLQLFMPDFSRVIAEPFNANHRSIGENFTYPLPFFNRPLNRLLFEAVVGPAAVALRCRNVDAVARAAAHLAFDENHEGAALPADITFTAFEASQGKTPRGGRDGGGKGPAGGFEQRLASVMAGDAALALESIVSMAVFDEPPTDISAWPLCEGQDTAAARANAVGAYLARAAGLVGAMVFSTNSALHLTEVDDAGPADPKDHSKPSFYRFFLVPGTHVAANPQVDREGHVVPGFEGRPTAPLVGGTQEFAGEHLAMLCGFSPALLAKMLFYLERCDGGVIVGRQEMDVFRYVADSNQTDVPCNLCTFDTRHACVHTTLMRLRARHPKFASAARGAIGVFGTMNSMYSDCDVLGNYAAFSALKRADGSETARTIMQETYRAATERVMAELETLQYVDQAVPTAMGRLETIITNREALHTVVNNVRQVVDREVEQLMRNLVEGRNFKFRDGLGEANHAMSLTLDPYACGPCPLLQLLGRRSNLAVYQDLALSQCHGVFAGQSVEGRNFRNQFQPVLRRRVMDMFNNGFLSAKTLTVALSEGAAICAPSLTAGQTAPAESSFEGDVARVTLGFPKELRVKSRVLFAGASANASEAAKARVASLQSAYQKPDKRVDILLGPLGFLLKQFHAAIFPNGKPPGSNQPNPQWFWTALQRNQLPARLLSREDIETIAFIKKFSLDYGAINFINLAPNNVSELAMYYMANQILRYCDHSTYFINTLTAIIAGSRRPPSVQAAAAWSAQGGAGLEAGARALMDAVDAHPGAWTSMFASCNLLRPVMAARPMVVLGLSISKYYGMAGNDRVFQAGNWASLMGGKNACPLLIFDRTRKFVLACPRAGFVCAASNLGGGAHESSLCEQLRGIISEGGAAVASSVFVATVKSLGPRTQQLQIEDWLALLEDEYLSEEMMELTARALERGNGEWSTDAALEVAHEAEALVSQLGNAGEVFNFGDFGCEDDNATPFGGPGAPGPAFAGRKRAFHGDDPFGEGPPDKKGDLTLDML
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: KRE1_YEAST
Sequence: MMRRTLLHSFATLLLSLSLWSAAVMAAVTTQVTVVTNVAGALVTETTIWDPATAAAAATTTAQTGFFTTVFTTTNDVGTTVTLTQTVNRATMLPTTTTSTSSTGKTTTTVPTATSSLSSGLYLSTVTTTNDLGTTVTLTQTFTHSSTSATSSASSSVSSSVSSSGSSSSVKTTTSTGSAVAETGTRPDPSTDFTEPPVSAVTSLSIDSYITITEGTTSTYTTTRAPTSMWVTVVRQGNTITVQTTFVQRFSSQYVTVASPSVGSIGMGTLTGTVGVIKSAIKKTVSHNEAQHLGMSSFTSILGGLLTVLIWFL
What is the function of this protein?
Involved in a late stage of cell wall 1,6-beta-glucan synthesis and assembly.  Has a structural, rather than enzymic, function within cell wall 1,6-beta-glucan assembly and architecture, possibly by being involved in covalently cross-linking 1,6-beta-glucans to other cell wall components such as 1,3-beta-glucan, chitin and certain mannoproteins.  Acts as the plasma membrane receptor for the yeast K1 viral toxin.
What are the official names of this protein?
Protein KRE1, Killer toxin-resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the KRE1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as GPI-anchored plasma membrane protein (GPI-PMP) as well as component of the cell wall. Concentrated at the surface of mother cells.
Protein: EXO1_SCHPO
Sequence: MGIKGLLGLLKPMQKSSHVEEFSGKTLGVDGYVWLHKAVFTCAHELAFNKETDKYLKYAIHQALMLQYYGVKPLIVFDGGPLPCKASTEQKRKERRQEAFELGKKLWDEGKKSQAIMQFSRCVDVTPEMAWKLIIALREHGIESIVAPYEADAQLVYLEKENIIDGIITEDSDMLVFGAQTVLFKMDGFGNCITIRRNDIANAQDLNLRLPIEKLRHMAIFSGCDYTDGVAGMGLKTALRYLQKYPEPRAAIRAMRLDKSLKVPVSFEKEFALADLAFRHQRVYCPKDKTLVHLSPPERELSVHEDAFIGSFFDNQLAIDIAEGRSNPITKCAFDIKDSSMQSFTKTTITISKRKGISKTDISNFFMKSIPPSKRPTKSTSLIDVTNVKVQRTHLANDISSEKQSIKSANEKAYVTPKSNSLKPGFGKSLSDISNSATKNENVPFLPPRTGVSKYFKLQKNTEKEIDEQVPSQSNNTTPTSAKSDSASPQNWFSSFSYQTPNSASPPFSSLSHTLPISALAKIGHDALNRKNHASLPSRRIVYKPPSSPSTPISMNPRPKGILSLQQYKFR
What is the function of this protein?
5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs.
What are the official names of this protein?
Exodeoxyribonuclease 1, Exodeoxyribonuclease I, EXO I, Exonuclease I.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: OBG_SYNY3
Sequence: MQFIDQAEIEVQGGKGGDGMVSFRREKYVPAGGPSGGNGGRGGSVIFEADANLQTLLDFRYARIFKAEDGKKGGSSNCTGANGKDVVVQVPCGTMVYDLDGECLLGDLVSPGQRLCVAAGGKGGLGNQHFLSNRNRAPEYALPGLEGEQRQLRLELKLLAEVGIIGLPNAGKSTLIAALSAARPKIADYPFTTLVPNLGVVRKPTGDGTVFADIPGLIEGAAAGIGLGHEFLRHIERTRLLLHVLDVTAGDPIANFRVIQQELDAYGRGITEKPQIIALNKIDALDGEMIGEIETELKRFSTAPCLHISAATRRGLDDLMQLVWQWLDEMAAADAEAQRLLELELQAQAAMNNPFNSDVPIDGVTYSS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_PELTS
Sequence: MAHKKGVGSSRNGRDSQPKMLGVKRADGQFVLAGSILVRQRGTRIHPGRNVGRGGDDTLFAKVDGVVSFERSGRDKKTVSVIPVEAAL
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: MINE_ACIBC
Sequence: MAGFWSKLFSSEEKPSSAQTAKDRLKVIVASEQGLGRRLSQDKIDQMKKEIMQVVSRYVSGVGEQHIQMQVRSEANIEMLEMNINLPEER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: FPG_KINRD
Sequence: MPELPEVEVVRRGVARWVVGRTVSSARFLHPRVTRRHVAGPDDAGARTRGLVVADAVRRGKYLWLPLATPDGRAEEAMVVHLGMSGQLLVEAADAPEEKHLRAVWTFDDGGEDLRFVDQRTFGGIAVVPLVATPDGGPGGLGETPDGSWSGSMPAPVAHIARDPLDPAFDDAVFARRLRERTTGLKRALLDQTLVSGVGNIYADEALWRAKLHYARPTRSVTPAQAAALLAGLREVMTAALDAGGTSFDSLYVNVNGASGYFDRSLAVYGQEGRPCPRCGALVRRDAFMNRSSFSCPVCQPVPRSPHW
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DER_NITSB
Sequence: MKKIAIIGKPNVGKSSLFNRILKQRDAIVSETEGTTRDVKRRIVQIGEKEAEILDTGGIEDRNELFEKVKQKSLEAAKDADIILYMVDGKKLPDEEDKQIFRSLQKLGKKIALVINKIDNDKEEENVWNFYEFGTQDIFPISVSHNRKVKRLLDWVEKQLPKKETIKIEIDEELDFDELLAINEGEKKQEESNEINVAILGRVNVGKSSLLNALLKEERSIVSDVAGTTIDTIDESTIYNDKVITFIDTAGIRRRGKIVGIEKYALNRTQKMLERADVALLVLDASEGITEQDERIAGYIDKYKLACIIVLNKWDIAKKSYEEAVKEVRDRFKFLSFAPIITLSAKTRKRVDRLYDLILKVYKNYSTWLPTGQLNRVIKEAQIRHQIPSYKGKPVKILYATQYDTKPPKIALVMNRPEGLHFSYKRYLANVLRENFDLEGTPIILRPRKRGERDEEMEEESY
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CRTX_PANAN
Sequence: MSHFAAIAPPFYSHVRALQNLAQELVARGHRVTFIQQYDIKHLIDSETIGFHSVGTDSHPPGALTRVLHLAAHPLGPSMLKLINEMARTTDMLCRELPQAFNDLAVDGVIVDQMEPAGALVAEALGLPFISVACALPLNREPDMPLAVMPFEYGTSDAARERYAASEKIYDWLMRRHDRVIAEHSHRMGLAPRQKLHQCFSPLAQISQLVPELDFPRKALPACFHAVGPLRETHAPSTSSSRYFTSSEKPRIFASLGTLQGHRYGLFKTIVKACEEIDGQLLLAHCGRLTDSQCEELARSRHTQVVDFADQSAALSQAQLAITHGGMNTVLDAINYRTPLLALPLAFDQPGVASRIVYHGIGKRASRFTTSHALARQMRSLLTNVDFQQRMAKIQTALRLAGGTMAAADIIEQVMCTGQPVLSGSGYATAL
What is the function of this protein?
Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside).  The reaction proceeds in two steps with the monoglucoside as an intermediate.
What are the official names of this protein?
Zeaxanthin glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: HLDE_SHEFN
Sequence: MKVSLPAFENARVLVIGDVMLDRYWVGPTGRISPEAPVPVVKINQIEDRPGGAANVALNIATLGGHVQLAGIVGQDETAQALTQGVKVFGVEPQWLTVADKPTITKLRVLSRNQQLIRLDFEEQFDKATSQALFAQSEAILDNVDVLVLSDYAKGAIDEPKDFIAKARAKGVKVLVDPKGHDFARYHGASLITPNMSEFEAVVGTVTSEDDLIEKAQKLIKLHDFEAILVTRSEKGMTLVSQNQPELHIPTVAREVHDVTGAGDTVISALATSIAAGASLAQACAIANTAAGVVVGKLGTSTVSRIELIQALALNHGESGFGVMTEDQLAYAMDQARLRGERIVMTNGCFDILHAGHVSYLQQAKALGDRLIVAVNDDSSVTRLKGPGRPVNPVDRRMAVLAGLASVDWVVPFTEDTPQRIITRLLPDSLVKGGDYKVEDIAGGAEVIAAGGKVEVLGFEDGVSTTAIIQNIMSQK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: CATB_RHOOP
Sequence: MTDLSIVSVETTILDVPLVRPHKFATTSMTAQPLLLVAVTTAGGVTGYGEGVVPGGPWWGGESVETMQAIVERYIVPVLLGRGVDEITGIMPDIERVVANARFAKAAVDVALHDAWARSLGVPVHTLLGGAFRKSVDVTWALGAAPAEEIIEEALDLVESKRHFSFKLKMGALDPAVDTARVVQIAQALQGKAGVRIDVNARWDRLTALKYVPRLVEGGVELIEQPTPGEQLEVLAELNRLVPVPVMADESVQTPHDALEVARRGAADVIALKTTKCGGLQKSREVVAIAKAAGIACHGATSIEGPIGTAASIHFACAEPGIDFGTELFGPLLFSEELLQEPIRYADGQVFLPEGPGLGVELNMDAVKTWTRN
What are the official names of this protein?
Muconate cycloisomerase 1, Cis,cis-muconate lactonizing enzyme I, MLE, Muconate cycloisomerase I.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: IBPA_SALPK
Sequence: MRNFDLSPLYRSAIGFDRLFNLLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIELERVIPEANKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDG_MOUSE
Sequence: MSSDTSPAVVTTPPPPSMPHKERYFDRINESDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPSGLLALQQIADYIVTSSFSGFSSPSLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLDEEEERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHGVAMSGGGGVNMASHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLVREKPRHKSDVEIPATVTAFSFEDDSAPLSPLKFMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSSGTPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFDDDDQGPPAPPNPFSHLLEGELEEYTKTIERKQQGLDDAEQGSLSDDAASVSQIQSQTQSPQSVPERLEENHELFSKSFTSMDAPVMIMNGKDEMHDVEDELAQRVSRLTTSTTIENIEITIKSPERTEEVLSPDGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA
What is the function of this protein?
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network.  Plays a role in actin filament capping.  Binds to calmodulin (By similarity).  Involved in myogenic reactivity of the renal afferent arteriole (Af-art), renal interlobular arteries and middle cerebral artery (MCA) to increased perfusion pressure.  Involved in regulation of potassium channels in the vascular smooth muscle cells (VSMCs) of the Af-art and MCA ex vivo.  Involved in regulation of glomerular capillary pressure, glomerular filtration rate (GFR) and glomerular nephrin expression in response to hypertension.  Involved in renal blood flow (RBF) autoregulation.  Plays a role in podocyte structure and function.  Regulates globular monomer actin (G-actin) and filamentous polymer actin (F-actin) ratios in the primary podocytes affecting actin cytoskeleton organization.  Regulates expression of synaptopodin, RhoA, Rac1 and CDC42 in the renal cortex and the primary podocytes.  Regulates expression of nephrin in the glomeruli and in the primary podocytes, expression of nephrin and podocinin in the renal cortex, and expression of focal adhesion proteins integrin alpha-3 and integrin beta-1 in the glomeruli.  Involved in cell migration and cell adhesion of podocytes, and in podocyte foot process effacement.  Regulates expression of profibrotics markers MMP2, MMP9, TGF beta-1, tubular tight junction protein E-cadherin, and mesenchymal markers vimentin and alpha-SMA (By similarity).  Promotes the growth of neurites (PubMed:33992672).
What are the official names of this protein?
Gamma-adducin, Adducin-like protein 70.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. Adducin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PA2HB_CERGO
Sequence: MRTLLIVAVLLVGVEGSVYELGKMILQETGKNAATSYGFYGCNCGVGRRGKPKDATDRCCFVHKCCYKKLTDCNSKTDRYSYSWKDKTIVCGDNNPCLQEMCECDKAVAICLRENLNTYNKKYKIHMKFFCKKPDAC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity (By similarity).  Is myotoxic (By similarity).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog Pgo-K49, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_RICCN
Sequence: MKRTFQPSNLVRKRRHGFRSRMATPTGRAILKKRRTKGRHKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PSAA_GLOVI
Sequence: MSTTPQEREKPVRVLVDNDPVPTSTEKWGKPGWFERNLARGPKTTTWIWDLHALAHDFETHTSDKEEISRKIFSAHFGHLAVVCVWLSGMFWHGAYFSNFTAWMENPLGLKPSAQTVWPVFGQEILNDPSTVAKGFEQGGIVITSGLFHLWRAVGFTTTGQLAAMSIAMLIIAALFLFAGWFHYHKRAPKLEWFQNVESMLNHHLAGLFGLGSLFWTGHLIHVALPVKAQLDAGIAPAQVNPFAGLDYGLMGQYFPKGFGPNGGLGAFFTLNWGQFTDFLTFKGGLEPATGALYLTDIAHHHLAIATLFIIAGHMYRTNWGIGHSIKEMLEAHKGPLTGEGHRGLYEVLTTSWHAQLAINLAMAGSITIIVAHHMYAMNPYPYMGTDYATQISLFTHHMWIGGFLIVGAGAHAAIFMVRDYDPVTNQNNLLDRVLRHRDAIISHLNWVTLFLGFHSFGLYVHNDTMQALGRPRDMFADFAIPLQPVFAQWIQNIHAAAPGGATAPWVGGTSPTWYTGALSSAATLQANQVLALANDKISISPIHLGTADFMVHHIFALCIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQSSAWDHVFLGLFWMYNTISVVIFHFSWKMQSDVWGTVDRSTGAVNHIIGNTDVLLGGQTVALSQYAASSININGWLRDFLWAQSSAVINSYGGPLSAYGLMFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSITQGRAVGVAHYLLGGIATTWAFFLARFLALP
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SAT_RUTMC
Sequence: MTKLVPPHGSDTLKSLALEGNALTVELERAKLLPKINCSSREEGDIIMMGVGGFTPLEGFMGKADWQSVCDNMTIESGLFWPIPITLSTDNEGVNQGDEVALVNGETDEIIATMVISEKYSIDKTHECNTVYKTTEIEHPGVVMVMAQGKYNLAGSIKVLSDGGFPEKYSSLYMTPMETRAYFDDKGWKTVAAFQTRNPMHRSHEYLVKIAVEVCDGVMIHSVLGNLKAGDIPANVRSEAISVLIENYFVDNTILQSGYPLDMRYAGPREALLHALFRQNYGCSHLIVGRDHAGIDDYYGPFDAHNIFDEIADDALMTKALKIDWTFWCHKCGGMSSMKTCPHSAEDRALLSGTKVRKMLSDSEDLPETFSRPEVAKVLQAYYAGIKDEDKVEIKLNGHSAK
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: 2AD1_SCHPO
Sequence: MKGIKSKMLSRGKSQDTQKSSKKKESKKSNSHDSSKAPKESPSTDPNGSVIGAQNDFLTVPKHSGKKVPIDTTPTPRDEILLENVRTVRKQRSSLYHISENRNLVRLPSFTDVPVNKWHSLALEKLEQCCVVFDFNDPSTDLYGKEVKREALQDLIDLISVRKEAIDESLYPSIVHMFAVNVFRPLPPPSNPPGEIMDLEEDEPALEVAWPHLHLVYDFFLRFFESPSLNTSVAKVYINQKFIRKLLVLFDSEDPRERDFLKTTLHRIYGKFLSLRAFIRRSINNLFLQFVYENEQFNGIAELLEILGSIINGFALPLKEEHKIFLSRVLIPLHKAKSLPLYYPQIAYGIVQFVEKDSSVTEEVVLGLLRYWPKVNSSKEVLFLNEIEDIIEVMEPSEFLKIQVPLFHKLATSISSQNFQVAERALYFFNNDYFVHLVEENVDIILPIIYPALFEISKSHWNRVIHSMVCNVLKLFMDINPSLFDEVDAEYSESRRKKEDEEIIREERWTILENIAKENAMKLKSQNPTTVHSTTERLKKLSLDYTNG
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.  Has a role in cell shape control and septum formation.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 1 isoform, PP2A, B subunit, B' delta 1 isoform.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSMG_DICNV
Sequence: MNDDFIAAEELLQRGAAALSFPVNQEVIEKLMHYLQLLAKWNRVHNLTAIREPQQQVIVHLLDSLVVAPFLPPAQTIADIGSGAGLPGIVLAIVCPQQQFFLVESNTKKSVFLREAVRQLALENVKVVAMRAEQWRPEAKLNVLISRAVSDINSFLMWTAALGDENSRWLLMKAHDDEVCTQKDFYVENVLPLTVPLLDAARVLFVVKKKS
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_ECOLC
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIADGHELSSVFFYREGVYNANQLTSPASDEFDLVRAWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSNLQQGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICHY_CAIMO
Sequence: ELDEGNGLRRPVCGEMAELLACPLVNLPVCGTDGNTYANECLLCVQKMKTRQDIRILNNGRCRDT
What is the function of this protein?
Inhibits chymotrypsin.
What are the official names of this protein?
Chymotrypsin inhibitor, DPCI.
What are the subcellular locations of this protein?
Secreted.