PharMolix/UniProtQA huggingface dataset:
Protein: SMBP2_MOUSE
Sequence: MASSTVESFVAQQLQLLELERDAEVEERRSWQEHSSLRELQSRGVCLLKLQVSSQRTGLYGQRLVTFEPRKFGPAVVLPSNSFTSGDIVGLYDTNENSQLATGVLTRITQKSVTVAFDESHDLQLNLDRENTYRLLKLANDVTYKRLKKALMTLKKYHSGPASSLIDILLGSSTPSPAMEIPPLSFYNTTLDLSQKEAVSFALAQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERLALCKKRILRLGHPARLLESVQHHSLDAVLARSDNAQIVADIRRDIDQVFGKNKKTQDKREKGNFRSEIKLLRKELKEREEAAIVQSLTAADVVLATNTGASSDGPLKLLPEDYFDVVVVDECAQALEASCWIPLLKAPKCILAGDHRQLPPTTVSHRAALAGLSRSLMERLAEKHGAGVVRMLTVQYRMHQAIMCWASEAMYHGQFTSHPSVAGHLLKDLPGVTDTEETRVPLLLIDTAGCGLLELEEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIAPYNLQVDLLRQSLSNKHPELEIKSVDGFQGREKEAVLLTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSHTVNNHAFLETLVDYFTEHGEVRTAFEYLDDIVPENYTHEGSQGHSRVPKPKCPSTSIRKPASDQESGQETRAAPRHGRRKPSEKPPGSHVQSQHSSSANGSDRTGGPDRTEHFRATIEEFVASKESQLEFPTSLSSHDRLRVHQLAEEFGLRHDSTGEGKARHITVSRRSPASSGSVAPQPSSPPSPAQAEPEPRAEEPVTVVQAHCPVQLDLKALHLERLQRQQSSQAQTAKGQPGGDSRPQKASQKKKKKEPKGPVMALPCEEDFDALVSAVVKADNTCSFSKCSVSTTTLGQFCMHCSHRYYLSHHLPEIHGCGEKARAHARQRISREGVLYAGSGTKDRALDPAKRAQLQRRLDKKLGELSSQRTSRKKEKERGT
What is the function of this protein?
5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction (PubMed:22965130, PubMed:8493094).  Specific to 5'-phosphorylated single-stranded guanine-rich sequences (PubMed:8493094).  May play a role in RNA metabolism, ribosome biogenesis or initiation of translation (PubMed:19299493, PubMed:19158098).  May play a role in regulation of transcription (By similarity).  Interacts with tRNA-Tyr (PubMed:19299493).
What are the official names of this protein?
DNA-binding protein SMUBP-2, ATP-dependent helicase IGHMBP2, Cardiac transcription factor 1, CATF1, Immunoglobulin mu-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, axon.
Protein: PEPT_STRP1
Sequence: MKYDNLLDRFIKYVKVNTRSVPDSETTPSTESQEAFALTILKPEMEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQGGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTSQPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMINALELAIDFHEKLPAKDRPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMTAIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERAVDVIIGLVCKA
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_VEREI
Sequence: MIENVMKEGFITTSYDSVVNWAKTGSLWPMTFGLACCAVEMIHSAAARYDLARFGAEVFRASPRQADLMIVAGTLCNKMAPALRKVYDQMSEPRWVLSMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGILQLQQKIRRSHTIARA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPB_DICT6
Sequence: MEGKIISVNGPVVDIYFPNDVPHIYEALEVENPIKNEKLVLETRILFGENKVRAIALGSTEGISRGLTVKRTFHPISVPVSEEILGRVVNVFGEPIDGGEKIRGEVTPIIKNAAEFRRVQPSYSILETGIKAIDLLTPFPQGGKIGLFGGAGVGKTVLIMELIHNVAVAHGGISVFAGIGERSREGNELWLEMKESGVLSKAALVFGQMNEPPGVRMRVPLTALTIAEYFRDYLGKDVLLLMDNIFRYVQAGMEVSSMLGRIPSAVGYQPTLITELGEVEERILSTDTGSITAVQAVYVPADDLTDPAPATIFSHLDSTLVLSRSIAEMGIYPAVDPLASSSQILEPKFVGYEHAEVARKVVEILQHYESLKDIISILGVEELSEEDRIIVNRARKIQMFLSQPLFVASAYTNIPGVYVPREKTIEGFKAIIEGEVDDLPEDAFYMVGTLEDVKKKAEEHGALMY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YBEY_CALS4
Sequence: MNVLIDNRQTKVDASGLEALVVRAIKATLEEEEVVDEVEVSVSFVDNEEIRKLNKYYRGIDSSTDVLSFPLMEFEEIEEGEEDEKDAEEIYPIGDIVISLEKAKEQAEEYGHSFEREVAYLTVHSMLHLLGYDHETEEERKLMREKEEKVMERLGLRR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKA2_RAT
Sequence: MEAEVDKLELMFQKADSDLDYLQYRLEYEVKINHPHSAGEKNAVAILKELSAIKSRYQALCARFKTVSVEQKETKSCICAILNKTMTMLQELQKQTNLELTLLTEEEKAVTERLKSHVPDVENGILQRNFDGEKISSKEIQRGV
What is the function of this protein?
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint.  The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies.  The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner.  In the complex, it is required for SKA1 localization.  Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Spindle and kinetochore-associated protein 2, Protein FAM33A.
What is the protein family that this protein belongs to?
Belongs to the SKA2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore- associated proteins.
Protein: CVP1_PIMHY
Sequence: MCRYALIVLVVVVVATNLSEANIFDVPTCEPNRIYKTCGPACPPTCEDPDPDCNETPQCKAGCFCIPGLIENMKGGNCISPSLCP
What is the function of this protein?
May be a phenoloxidase inhibitor that stabilizes or inhibits venom phenoloxidase while it is stored in the venom sac.
What are the official names of this protein?
Cysteine-rich venom protein 1, cvp1.
What is the protein family that this protein belongs to?
Belongs to the serine protease inhibitor-like (TIL domain-containing) family.
Protein: YL017_MIMIV
Sequence: MTTIISGLRFRGKICDENRVTETIEENNQENNKKFIEEFYPDKESDKNFSDDDSDDSDDSDDSENSDEEFDNKFTEKKPIGQYINIIDKMCRNKSDKEFLRKTIKNSIGYFDWTVQDRDKIYDFTQKKFGFKKLVCVKDNMEPIIELLALVLIPDSVDIIKSKNSNYKNQIKTDIMYVHSLFVLQNSNSEILDKDFANNLPQYQIPIDFFSKYYCVEGTGDMKRYYPSALIKKSFVKGITFFLDFNDAQKIKIMDDLDKLSISNLKKREIATAMFILNLESMINDSIINEKRALEKLKALTKGNLIGIVNHLNNMKIGRDVIEMMIIEDTLNHSHSNKIKELENKITELKYQNEIN
What are the official names of this protein?
Uncharacterized protein L17.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L17/R827 family.
Protein: MOS_PATPE
Sequence: MPCDTADNWARYEGQDNAIMVARRGSVNSAFVTNSSQYHQAEDTNGNCFINARNDNWDNRDCNACVGHSDFSIDGVIGSGGFGSVFLGRYCGRRVAVKSVRQCSRNKEASRQSFQAEFNALLLRHDNIVSVLATTAYEDFDSGAFIIMEYAGRNLQQIVNDPGSSLSPTRRTKYALHIIRALHYTHSQGIAHLDVKPANVIVDSNTDVCRLADFGCSQRVSEGEGRDSFTSRSYLTGTFAYRAPELLRGRPPTTKADIYSYGVTLWQMLTRETPFAGENHHVVIFGVVAQNLRPSLPENANDAWYESLVTRCWEGRVADRPSAAEILLALERRTDDTENLPRDLKRRHGTT
What is the function of this protein?
Suppresses the mitotic cell cycle in oocytes, forcing them to undergo meiosis II to produce haploid gametes.  Acts as a MAPK kinase kinase (MAP3K) that acts upstream of MAP kinase in oocytes.
What are the official names of this protein?
Serine/threonine-protein kinase mos, Oocyte maturation factor mos.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RL6_EXIS2
Sequence: MSRIGKKPVVIPAGVTVTVENSTVTVKGPKGELTREFNPTMAINVEGNELTVTRPNDEKANRTIHGTTRALIANMVEGVNNGFAKTLDIQGVGYRAQKQGNKIVLNLGYSHPIEYTPEQGIEVEVPTNTQIIVRGISKERVGHVAALIRSYRQPEPYKGKGIRYSDEVVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DCDB_MYCA1
Sequence: MLLSDRDLRAEITAGRLGIEPFDDALVQPSSIDVRLDCMFRVFNNTRYTHIDPAKQQDELTSLVEPQDGEPFVLHPGEFVLGSTLELITLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCILRLTSPAEHPYGSTRVGSKYQGQRGPTPSRSYQNFITST
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: Y1178_STRPS
Sequence: MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SPCG_1178.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TAT_SIVG1
Sequence: MDKEEEPHPLLQDLHRPLQPCTNKCYCKKCCYHCELCFLQKGLGVRYHVSRKRRKTSTQDNQDPIRQQSISTVQRNGQTTEEGKTEVEKAAAAN
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: BGLX_DICCH
Sequence: MEKSATRQKALLIALPLLFSPLASAVQQAVLDTRGAPLITVNGLTFKDLNRDGKLNPYEDWRLPAAERAADLVSRMTLAEKAGVMMHGSAPTAGSVTGAGTQYDLNAAKTMIADRYVNSFITRLSGDNPAQMAEENNKLQQLAEATRLGIPLTISTDPRSSFQSLVGVSVSVGKFSKWPETLGLAAIGDEELVRRFADIVRQEYRAVGITEALSPQADLATEPRWPRIDGTFGEDPDLTKKMVRGYVTGMQNGKNGLNAQSVISIVKHWVGYGAAKDGWDSHNVYGKYAQFRQNNLQWHIDPFTGAFEAHAAGIMPTYSILRNASWHGKPIEQVGAGFNRFLLTDLLRGQYGFDGVILSDWLITNDCKGDCLTGVKPGEKPVPRGMPWGVEKLTPAERFVKAVNAGVDQFGGVTDSALLVQAVQDGKLTEARLDTSVNRILKQKFQTGLFERPYVNATQANDIVGRADWQQLADDTQARSLVLLQNNNLLPLRKGSRVWLHGIAANAAQEVGFIVVNTPEQADVALIRTHTPYEQPHKNFFFGSRHHEGSLAFRNDNPDYQAIVRASAKVPTLVTVYMERPAILTNVVDKTRAVVANFGVSDSVLLNRLMSGAAYTAKLPFELPSSMSAVRNQQPDLPYDSAKPLFPFGYGLPH
What is the function of this protein?
Exhibits both beta-glucosidase and beta-xylosidase activities.
What are the official names of this protein?
Periplasmic beta-glucosidase/beta-xylosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: COXX_VEREI
Sequence: MSAAPPVAVSAPSRLRQFYALTKPRVVQLIVFCALIGMVLAVPGLPSAAQWGRIAWACAGVWLVAGAAAAFNCIVEQGIDAKMKRTAWRPTARGELSNAQTLLFSALLCVAGSALLYFLVNPLTMWLTFATFVGYAVIYTLILKPLTPQNIVIGGASGAMPPVLGWAAMTNTVGPEALILFLIIFLWTPPHFWALALYRVEEYRQSGLPMLPVTHGSAFTRLQVLLYTLILFAACLMPFIYGMSSWPYLAAAVLLGAGFCGYGFALWRNYSDALARKTFRFSLIHLSALFAALLLDHYLP
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPB_BORBR
Sequence: MIKWLARPADYGSVWDAMKAFTAARGPGTADEIWLCEHAPVYTLGQAGRPEHLLNPGLIPVVHCDRGGQVTYHGPGQVLAYTLFDLRRAGLYVREYVDMLEQATLATLRELGLEQACRKPGAPGIYVPQPGGELAKIAALGVKVRNGYAYHGLALNIDMDLSPFLGINPCGYEGLRTVDLAACGVRTSVERAGELLAAQLARAHGQAVQQRAAALAGVPG
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR277_MIMIV
Sequence: MDRQLIIVIGLPGSGKTHLCREISSLDSSRQIVDDFIGSFYNGNVMNLLTGKCKLCINDPRLCLKNVFKRFIKIFEQDIGQENIYLILFENNPEQCKFNVQNRNDNRKGILEIVDQYSQRYDIATYSKYDYEIRTVFK
What are the official names of this protein?
Uncharacterized protein R277.
Protein: RNT_SHEB5
Sequence: MSDICDANKLKYRFRGYFPVVIDVETAGFNSQTDALLEIAVTLLKMDNEGVIGIDKTLHFHIEPFEGANLEPEALAFNGIDPTNPLRGAVSEKEAFLEIFKAVKKAQKASDCHRSIIVAHNAAFDHGFVSKAIERCDLKRSPFHPFATFDTATLAGLAIGHTVLAKACIMAGIPFDNKEAHSALYDTERTAELFCHIVNRWKSLGGWPLLAVDEQDAQSDTEA
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: PSBB_HORVU
Sequence: MGLPWYRVHTVVLNDPGRLLAVHIMHTALVSGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITDSWGGWSISGGTVTNPGIWSYEGVAATHIVFSGLCFLAAIWHWVYWDLEIFSDERTGKPSLDLPKIFGIHLFLAGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQAVNPAWGAEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSNGLAENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRDKEGRELFVRRMPTFFETFPVVLVDEEGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVNYSDPATVKKYARRSQLGEIFELDRATLKSDGVFRSSPRGWFTFGHATFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGTFQKVGDPTTKKQAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RLME_SALA4
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_HAES1
Sequence: MEELNTIKLSDHLTPFLTFNRQQWAELRKSVPLKLTEQDLKPLLGFNEELSLEEVSTIYLPLARLINYYIEENLRRQTVLKRFLSGHNPKVPYIISIAGSVSVGKSTSARILQSLLANWPVARKVDLITTDGFLYPLEILQKKNLLQKKGFPISYDTQRLIRFLADIKSGKKNVKAPIYSHLTYDIIPNQFDIVDRPDILILEGLNVLQIGTNKSNQMFVSDFVDFSIFVDAEEDQLKEWYIKRFLKFCRSAFTDPNSYFKHYANLSEQEAIETASQIWDNINGLNLKQNILPTRERANLILKKGENHKVELVKLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_RICRO
Sequence: MHKLIIHGGTPLKGSINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKDLLRSHGADIEIIKHQDEFELIIDTKNINNFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKAMGAEIEIEDGYINASSKGRLKGTHFVFDKVSVGATINAILVAVLAEGETVLFNCGREPEIVDLCNCLITMGADIAGIGTSEITIKGKDSLNKASYKVLSDRIEAGTYMFAAAITKGDVKICGIDYHIVENIALKLIETGIKVVPINNGVQVTYEGKLNSVDLETNPYPGFATDLQAQFMSLMTLSSGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDRGFQDLEKKLSNCGADIKRV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRI_METMJ
Sequence: MSAKDPSRGLLVSPIKNGTVIDHITAGEALNVLRILGITGSTRECLSIATNVESKRMGKKDIVKIENRELRTEEVDRIALLAPQAKINIIRNYKVVEKKGVEIPEVIRGVVRCPNPGCITNTDEPVASTFEVLDKGLHCLYCDWLIKDDIANHII
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: ENO_CORDI
Sequence: MADIMHVFAREILDSRGNPTVEAEVFLDDGSHGVAGVPSGASTGVHEAHELRDGGERYLGKGVLNAVNNVNEEIADAIAGAEADDQRLIDQAMIALDGTENKSRLGANAILGVSIAVAKAAAESAGLPLYRYIGGPNAHVLPVPMMNIVNGGAHADSGVDVQEFMIAPIGAESFSEALRMGAEVYHSLKSVIKSKGLSTGLGDEGGFAPSVESTKAALDLIVEAIEKAGFKPGADIALALDVASSEFYKDGKYHFEGGEHTAEEMAKVYEQLIAEYPIVSIEDPLQEDDWEGYTALTAAIGDKVQIVGDDFFVTNPARLKEGIEKKAANALLVKVNQIGTLTETFDAVDLAHRNGYRTMMSHRSGETEDTTIADLAVALGCGQIKTGAPARSERVAKYNQLLRIEQQLDDAAVYAGRSAFPRFQG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL7A_YEAST
Sequence: MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKSMN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L7-A, L6, Large ribosomal subunit protein uL30-A, RP11, YL8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y046_AFV2P
Sequence: MALSSTMWCTFLSMMLTALLSCHQQVILMRHILLKLFHNSLHKAML
What are the official names of this protein?
Uncharacterized protein ORF46.
Protein: ZRAN1_XENTR
Sequence: MTEHGIKWACEYCTYENWPSAIKCTMCRAPRPSGAIITEEPFKNSTPDVGSMERESGSPLICPDSSARPRVKSSYSMETSTKWSCHMCTYLNWPRAIRCTQCLSQRRTRSPTESPQSSGSSLRAIPSPIDPCEEYNDRNKLNIKGQHWTCSACTYENCAKAKKCVVCDHPTPNNMDAIELANTDEASSIINEQDRARWRGGCSSSNSQRRSPPTSKRDSDMDFQRIELAGAVGSKEEFELDLKKLKQIKNRMRKTDWLFLNACVGVVEGDLSAVEAYKTSGGDIARQLSADEVRLLNRPSAFDVGYTLVHLSIRFQRQDMLAILLTEFSQHAAKCIPAMVCPELTEQIRREIAASVHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINWSLELGTRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHWFYSRWKEWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGFDNRGAGANLNTDDDVTVTFLPLVDSERKLLHIHFLSAQELGNEDQQEKLLREWMDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDGYRQIRPCTALSDGEEDEDDEDE
What is the function of this protein?
Ubiquitin thioesterase, which specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin (By similarity).  Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones (By similarity).  Positive regulator of the Wnt signaling pathway that deubiquitinates apc protein, a negative regulator of Wnt-mediated transcription (By similarity).  Acts as a regulator of autophagy by mediating deubiquitination of pik3c3/vps34, thereby promoting autophagosome maturation (By similarity).  Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).  Required in the stress fiber dynamics and cell migration (By similarity).
What are the official names of this protein?
Ubiquitin thioesterase zranb1, Zinc finger Ran-binding domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C64 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Protein: MINE_BURCJ
Sequence: MSILSFLLGEKKKSASVAKERLQLIIAHERVGGRPPADYLPALQKELVAVISKYVHISNDDIRVSLERQDDLEVLEVKIEIPQA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.