PharMolix/UniProtQA huggingface dataset:
Protein: TRM2_HHV8P
Sequence: MEYASDQLLPRDMQILFPTIYCRLNAINYCQYLKTFLVQRAQPAACDHTLVLESKVDTVRQVLRKIVSTDAVFSEARARP
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.
What are the official names of this protein?
Tripartite terminase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM2 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: RUTA_ECO24
Sequence: MQTSHYAAEKDMQDAVPRLTFTLRDEERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGSGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: NTPPA_GEOSM
Sequence: MKNSSIVLASASPRRSELLESAGIQFRVVPADINEEPLPGEEPVDHVQRLAEGKARAAAELAEGRFFLGADTIVLCDGEIMGKPKDAVDAERMLKKLSGVPHEVVTGFAIYDRERKGAVVEAVRTKVFFKHLRDEEIRDYVATGCPFDKAGAYAIQGGAAHMVRKIEGSYTNVVGLPLCEVVDALRVIGALGN
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXB_ECO8A
Sequence: MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGVQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: RS2_STRA3
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVAEEAKRAGQYFINHRWLGGTLTNWGTIQKRIARLKEIKRMEEEGTFELLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVMYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITSKLADAVIEGRQGEDADVDFAQEAQADSIEEIVEVVEGSNND
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PSD_BACCN
Sequence: MRRTLYRLMIELTNGRFTSYILRKFAQSRFSSIIIPSYAKVFQINQDEMEKDLKEYRTLHELFTRKLKEGKRMIHAEAAAVVSPVDGIFADFGPIEESKTFDIKGKRYSIVDMLGNEERASRYAGGTYVVIYLSPSHYHRIHSPLSGTVTERFELGGKSYPVNAAGMKYGKEPLSKNYRSVTEVDSEGKRMALVKVGAMFVNSIELLHKRNTVQKGEEMAYFTFGSTVVLLFEKGMIEAVSTLTSGQELRVGEKIATRLTS
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GSTX3_TOBAC
Sequence: MAEVKLLGFWYSPFTHRVEWALKLKGVKYEYIEEDRDNKSSLLLQSNPVHKKVPVLIHNGKPIVESMVILEYIDETFEGPSILPKDPYDRALARFWSKFLGDKVAAVVNTFFRKGEEQEKGKEEVYEMLKVLDNELKDKKFFVGDKFGFADIAANLVGFWLGVFEEGYGVVLVTSEKFPNFSRWRDEYINCSQVKESLPSRDELLAFFRARFQAVVASISAPK
What are the official names of this protein?
Probable glutathione S-transferase, Auxin-induced protein PCNT103.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. HSP26 family.
Protein: TAL_YERPE
Sequence: MTDKLTSLRQITTVVADTGDIAAMKLYQPQDATTNPSIILNAAQIPEYRKLIDEAIAWAREQSSDHAQQIVDATDKLAVNIGLEILKLIPGRISTEVDARLSYDTVASVAKAKRLIKLYNEAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANGDQKEFAPSEDPGVVSVTEIYQYYKKHGYKTVVMGASFRNLGEIIELAGCDRLTIAPSLLKELAESEGPVERKLAYTGEIQAKPAPLTEAEFYWQHNQDPMAVDKLADGIRKFAIDQGKLEKMISDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB_BLUHO
Sequence: MREIVHLQTGQCGNQIGAAFWQTISGEHGLDGSGVYNGTSDLQLERMNVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICMRTLKLSNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVTVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVSMKEVEDQMRNVQQKNVSYFVEWIPNNVQTALCSIPPRGLKMSSTFVGNSTSIQELFKRVGDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEASISEGEEEYPEEVSNEEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ARGJ_PSYA2
Sequence: MAVGNVAVPETIYPIEGIKLSATAAGVRYKDRDDLVVIEIATDAATAVVTTKNAFCAAPVRVLREHFAKASPRYLVTNTGNANAGTGADGKRRAIDICAALAAKAGVNNNTVLPFSTGVIGEPLNSEAIIAGLDNALANLAPDNWLAAANGIRTTDTIPKLTSKKVNVAGSHYHITGMSKGSGMIRPNMATMLGYVATDANIAADLLQEMLSAINEQSFNRITVDGDTSTNDCCVLIATGAASSDIIDSPEHPHYQPLFDALAEVFIRLAQLIVRDGEGATKFMTVKVTGGKTTQECCDVAYAVAHSPLVKTAFFASDANWGRILAAVGYAGVEDLDTEQVDVYLDEVMICQNGGVAPTYTEEAGKTVMSRPEITIHIDLARGEAIDTVYTCDLSYDYVKINADYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWD3_YEAST
Sequence: MFQFVTPVGTQNGLKATCAKISPDGQFLAITQGLNILIYDINRRTVSQTLVTSHARPFSELCWSPDGQCIATASDDFSVEIIHLSYGLLHTFIGHTAPVISLTFNRKGNLLFTSSMDESIKIWDTLNGSLMKTISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCLKTLTYDKDWKRENGVVPISQVKFSENARYLLVKSLDGVVKIWDCIGGCVVRTFQVQPLEKGVLHHSCGMDFLNPEDGSTPLVISGYENGDIYCWNSDTKSLLQLLDGSLYHHSSPVMSIHCFGNIMCSLALNGDCCLWRWV
What is the function of this protein?
The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
What are the official names of this protein?
COMPASS component SWD3, Complex proteins associated with SET1 protein SWD3, Set1C component SWD3.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: LS14A_PONAB
Sequence: MSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCEPPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTRSLKTQLSQGRSSPQLDPLRKSPTMEQAVQTASAHLPAPAAVGRRSPVSTRPLPSTSQKAGENPEHRRAEVHKVSRPENEQLRNDNKRQVAPGAPSAPRRGRGGHRGGRGRFGIRRDGPMKFEKDFDFESANAQFNKEEIDREFHNKLKLKEDKLEKQEKPVNGEDKGDSGVDTQNSEGNADEEDPLGPNCYYDKTKSFFDNISCDDNRERRPTWAEERRLNAETFGIPLRPNRGRGGYRGRGGLGFRGGRGRGGGRGGTFTAPRGFRGGFRGGRGGREFADFEYRKDNKVAA
What is the function of this protein?
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for translationally inactive mRNAs and protect them from degradation.  Acts as a repressor of mRNA translation.  May play a role in mitotic spindle assembly.
What are the official names of this protein?
Protein LSM14 homolog A, Protein FAM61A, RNA-associated protein 55A.
What is the protein family that this protein belongs to?
Belongs to the LSM14 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm, cytoskeleton, spindle. Cytoplasm, Stress granule.
Protein: SPB10_HUMAN
Sequence: MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP
What is the function of this protein?
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF.  May regulate protease activities in the cytoplasm and in the nucleus.
What are the official names of this protein?
Serpin B10, Bomapin, Peptidase inhibitor 10, PI-10.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mostly found in the nucleus.
Protein: DAPE_BURPS
Sequence: MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLEQWSSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: ATPL_ACTPJ
Sequence: MESVITATIIGASILLAFAALGTAIGFAILGGKFLESSARQPELASSLQTKMFIVAGLLDAIAMIAVGISLLFIFANPFIDLLK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZN257_HUMAN
Sequence: MGPLTIRDVTVEFSLEEWHCLDTAQQNLYRDVMLENYRNLVFLGIAVSKPDLITCLEQGKEPCNMKRHEMVAKPPVMCSHIAEDLCPERDIKYFFQKVILRRYDKCEHENLQLRKGCKSVDECKVCKGGYNGLNQCLITTQSKMYQCDKYVKVFYKFSNSDRHKIRHTEKKTCKCKECGKSFCMLSQLTRHKRIHIRENSHKCEECGKAFNQSSALTRHKMTHTGEKPYKCEECGKAFNRSSHLTQHKVIHTREKPYKCEECGKAFNRSSHITQHKRIHNREKPFKYDECCKAFKWSSALTTLTQHKRIHTGEKPYKCEECGKAFNQSSALTRHKMIHTGEKPFQCEECGKAFNRSSHLTQHKIIHTKEKPYKCEECGKAFNRSSHLTKHKRIHTREKAYKCDEYCKAFNWSSALTTLTQHKIIHTGEKPYKCEECGKAFNRSSYLIRHKIIHTGEKPYKCEECGKAFNQSSHLTQHKIIHTGEKPYKCEECGKAFNRSSHLSQHKIIHTGEKPYKCEECGKPFNRFSYLTVHKRIHAGENPNKYEECGKACNHSSNLTKHNS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 257, Bone marrow zinc finger 4, BMZF-4.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDTL_ECOLC
Sequence: MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWAMAMMGIAVLMLSLFILKETRPASPAASDKPRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA
What is the function of this protein?
Confers resistance to chloramphenicol.
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS8_STRZP
Sequence: MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREGFVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLGIAILSTSEGLLTDKEARQKNVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: 5NTC_CHICK
Sequence: MTTSWSDRLQNAADLPANMDGHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFDLTVERLVSIGYPHELLNFVYDPAFPTRGLVFDTHYGNLLKVDAYGNLLVCAHGFNFLRGPETRDQYPNKFIQRDDTDRFYILNTLFNLPETYLLACLVDFFTNCDRYTSCETGFKDGDLFMSFRSMFQDVRDAVDWVHYKGSLKEKTLENLEKYVVKDGKLPLLLSRMNEVGKVFLVTNSDYKYTDKIMTYLFDFPHGPKPGSAHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTVTGKLKIGTYTGPLQHGIVYSGGSSDTVCDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSALFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINEKESPMATRNRTSVDFKDSDYKRHQLTRSISEIKPPNLFPQAPQEITHCHDEDDDEEEEEEEVEEEEEEEE
What is the function of this protein?
Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates (PubMed:6060459).  In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine (By similarity).  Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP (PubMed:6060459).  Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency (By similarity).  Through these activities regulates the purine nucleoside/nucleotide pools within the cell (PubMed:6060459).
What are the official names of this protein?
Cytosolic purine 5'-nucleotidase, Cytosolic nucleoside phosphotransferase 5'N.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RS14_ANAPZ
Sequence: MSRKSVVQRNLKRVAISAALSEKRKALVAIIKDESLSMSERFAAQLKLSKMPRDSSYIRIRNRCLITGRPRGYYRKFKMSRIVLRQLGSIGQIPGLTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RL25_STRCO
Sequence: MSEVKLTAETRTEFGKGAARRIRRDNKVPGVLYGHGSDPLHLTLPGHELLLALRTSNVLIALDIDGKTNELAIPKSVQRDPIKGFLEHVDLQLVKRGETVSVEIPVQAEGELAPGGFLLEYVLDALPVEAEATHIPQQVTVSVAGLEAGASIHAKDIALPSGVKLDVDGDTVVLQVLSAQAEEAPAEGEGEGEGAAEA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: COXX_LISMF
Sequence: MNQIEKTGELSASRFTVRDFTELVKIGIVNSNTITAFTGMWLAFQLNGISFIQNVDVIFFTIVGSALIVAASGAFNNVIDRDIDGIMERTKNRPTMTGKISGKRALMVALVLGVVGTIMLFMTTWQAGVLGVIGVFLYVVVYSLYAKRKLVSNTVIGSFSGAVPPLIGWFAVEPSFSIVPIMLFLVMFCWQPPHFYAIAIKRKEEYAAAGIPMLPVVKGIERTKKSMFFWVILLTILPFFMFELGIVYVVLATLLNIGWLALSIYGFKMEDSIKWAKWMFVYSLNYMTILFVAMVVISIFL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACEA2_MYCTO
Sequence: MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGVKELNGHLLYALGDSEYAAAGGWLERQGIFGLVSDAVNAWREDGQQSIDGIFDQVESRFVAAWEDDAGLMTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA
What is the function of this protein?
Involved in the persistence and virulence of M. tuberculosis.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
What are the official names of this protein?
Isocitrate lyase 2, ICL2, Isocitrase, Isocitratase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: RSMA_ANAPZ
Sequence: MKITKYRTKKSLGQCFILDPAIAEKIVSYAGCLEQYNVIEVGPGLGIMTQSILNKEVRRLTAIEKDRRLSNIHSKLKEAHAEYDCIFEDILDVNIEQLLSQSPLKMISNLPYNISVILLLKLLPYIHRFEKLILMFQKEVADRIVAQPNTKSYSILSILVQLLCDVRKVEDFPPEIFSPSPKVYSSVIEITPLLSPRFSVDNSYFAQVLKKLFHCRRKTIRNSLKSCIKDADALFIGCNIDPNARAESLTIEQLCSLTNALKARNINII
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_XANCB
Sequence: MARTTPIERYRNFGIMAHIDAGKTTTSERILFYTGVSHKIGEVHDGAAVMDWMEQEQERGITITSAATTAFWTGMDKSMPQHRFNIIDTPGHVDFTIEVERSLRVLDGAVFVLCAVGGVQPQSETVWRQANKYSVPRMAFVNKMDRTGANFDKVVEQLKARLGAYAVPMQVPIGAEDGFEGVVDLLKMKAIHWDTASQGTTFEYRDIPADLVDVATEARSFMVEAAAEASEALMDKYLNDGDLSEDEILSGLRERTLKVEIVPVFCGSAFKNKGVQAMLDGVVHLLPSPADRPPVQGIDENEKEDTRDATDTAPFSALAFKIMTDPFVGSLTFFRVYSGTLNSGDQVYNPVKSKKERVGRILQMHSNNREEIKEVRAGDIAAAVGLKDVTTGDTLCAQDKIITLERMVFPEPVISMAVEPKTKSDQEKMGMALGRLAQEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFNVEANVGKPQVAYRETIRKSDVKSDYKHAKQSGGKGQYGHVVIELSPMTEEDRKNDSVKDDFLFINDITGGIIPKEFIPSVEKGLRETITSGPIAGFPVVGVKVKLVFGSYHDVDSSEMAFKLAASMAFKQGFAKASPVLLEPIMKVEIVSPEDYLGDVMGDVSRRRGVLQGQDDSPSGKIINAMIPLGEMFGYATSLRSMSQGRATFSMEFDHYEEAPANIADAVTKKG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_SALTI
Sequence: MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLESENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSLESAQREIAFFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEP15_BOVIN
Sequence: MAARRDGWLGPAFGLRLLLATVLQTVSALGAEFSSESCRELGFSSNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCGUKLGRFPQVQAFVRSDKPKLFKGLQIKYVRGSDPVLKLLDDSGNIAEELSILKWNTDSVEEFLSEKLERI
What is the function of this protein?
May be involved in redox reactions associated with the formation of disulfide bonds (By similarity).  May contribute to the quality control of protein folding in the endoplasmic reticulum.  May regulate protein folding by enhancing the catalytic activity of UGGT1/UGCGL1 and UGGT2/UGCGL2 (By similarity).
What are the official names of this protein?
Selenoprotein F.
What is the protein family that this protein belongs to?
Belongs to the selenoprotein M/F family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=The association with UGGT1/UGCGL1 is essential for its retention in the endoplasmic reticulum.