PharMolix/UniProtQA huggingface dataset:
Protein: HIS1_ACIF5
Sequence: MSTGITIALSKGRILQEAIPLFAGAGIHLAEDPEESRKLIIPSTDPTVRFLVIRASDVPTYVTWGAADVGIAGKDVLLEQEGLDLYEPLDLRIGICHMAVAEPAAMAADDAPQSWERVRIATKYPHITRHYFHSRGVQTEIIKLYGSMELAPLVGLADRIVDLVSSGRTLKENGLVEVEEIMPISSRLVVNRAAMKLKRRAIETLIRQLEAQVTP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_YERPB
Sequence: MVRFESTDSLMLARQLPNKTVALILAGGRGSRLKDLTATRAKPAVHFGGKFRIIDFALSNCLNSGVRRIGVITQYQSHTLVQHIQRGWSFLNEEMNEFVDLLPAQQRLSTEQWYKGTADAVCQNLDIIRRYDAEYIVILAGDHIYKMDYSRMLLDHVEKGAECTVACIPVPISEGSEFGIMEVTADYQITAFYEKPANPPPIPGDPSNALASMGIYIFNADYLFKLLEEDNNTPGSSHDFGKDIIPQLTARKVVWAHPFDLSCVTSNAELPPYWRDVGTLDAYWRANLDLASVTPELDMYDRAWPIRTHMEPLPPAKFVQDRSGSHGMTMNSLVSGGCIVSGSVVVHSVLFPRVRVNSFCTIDSSLLLPDVHVGRSCRLRRCIIDRACHIPEGMVIGENANEDSARFYRSEGGVVLVTRDMLAKLEAK
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: YO019_YEAST
Sequence: MISVCPQNDLQKCYRSLTFDVPGQQFEERNEQNLKKRAKKKGSFQPSVAFDTVPSTAGYSSIDDSREGFKGVPVPNYYTMEECYDDETDSFSPNLQYYLRDTFQSSPFLNTRKENKSESSSFPMRSSKLLEKNSDIKKYFLVSKNGKIVRRDYPSTPVIVNETLMINRFEKNWIKLWRQRKLQINERLNDKKKWFTYPELIFSEERIKPLYRGDDSAPCTKEQKRKHKILQQKVGYPNNPKTIVCHINGKKHTWVALDWTVYKFARNLDHIVVITTLPKMISNRKKTAKDDTEWAPGYQKEVIDQKLNDIFDYILQLVKVVKISVKITLEIIVGKIKKSLVDVINVHTPDFLVLATLKHERNENLITYKSKKLTDVFPVSYPIPTFVVPSKRMYSFELNLQREVNEHYVSKNHMKHEHTDVESMSSSMFKKNTISDISSHISVDSYAEDFKRQGYIKKQFNTSNDSIPRKLTGLAQHSRRKITGDIEKLQDDEKDRECTKEKLLLKKIDIIIRESLKSSLAIETLPGKNVSQSSHGDQISSFKNALIGNGSKNTKFRKSLIPYSSSEEQNTTTTIKLSSSPTSQIKFATSVKHKDGRAALGKARNLPDIRHSISFDKENSFDPSDKSSSVDNSIPLRKVKSAGALRKVKTNDSSSSAGSKKSSSSFSTVNTFTGGGVGIFKVFKSGSSSGNKSSSRRNSSSGDVFESDDRNDKKKKKKKKKKSLFLFGKI
What are the official names of this protein?
Uncharacterized protein YOR019W.
Protein: RS5_HELAH
Sequence: MTERKGMEEINREEFQEVVVNVGRVTKVVKGGRRFRFNALVVVGNKNGLVGFGLGKAKEVPDAIKKAVDDAFKNLIHVTIKGTTIAHDIEHKYNASRILLKPASEGTGVIAGGSTRPIVELAGIKDILTKSLGSNNPYNVVHATFDALAKIKA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ATG29_YEAS7
Sequence: MNSTNTVVYIKVKGKRPQGFLDPPKFEWNGTKERQLWTMVSNLNYSQDQIDWQNLSKIFETPEFFLKKRTYKLFAEHLELLQLQLEKKRDLEKYSNDQVNEGMSDLIHKYIPTLQNDNLLNVSASPLTTERQDSEEVETEVTNEALQHLQTSKILNIHKKTSDSENKPNDKLDKDGINKEMECGSSDDDLSSSLSVSKSALEEALMDRL
What is the function of this protein?
Plays a role in autophagy.  Functions at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions.  Also plays a role in mitophagy and regulation of filamentous growth (By similarity).
What are the official names of this protein?
Autophagy-related protein 29.
What is the protein family that this protein belongs to?
Belongs to the ATG29 family.
What are the subcellular locations of this protein?
Preautophagosomal structure. Note=Localizes also to other perivacuolar punctate structures.
Protein: COFC_METSF
Sequence: MKVLIPVSPINSLKTRLSEFLSSEERKNLLLNMLRDINKALEGLDVVIISRDEEILEFGKNELKAETIKEKYKGLNKAIKQAFEEIEDDEVIIIPADIPLIKKRHIEDILKLSKDYDVIIAPSRGGGTNLLYLKSKNLIEIKYEGFSFLKHLEEAKKKNLRYYIYDSFLISVDINTPEDLGEIFIHGDSTYTKNYLKGLGIEVESKHSSAGRFVVKRGGDNEVSNPM
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
2-phospho-L-lactate guanylyltransferase, LP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: MNME_THEM4
Sequence: MFDTIAAVSSPHGTGAIAVIRIDGPKSHDIAKKLTGLNKVEYRRVYTTYLNFEGDILDQVNIVFFKSPNSYTGNDLIEIYTHGGILVTQNVLDAILKSGARIAKRGEFTKRGFLNGKISLVQAEAIYQIIEAKSEVSLKMSLQNLKGKLGEEIEYYRGEILNVLSEIEVTFDYPDDIELDEKSILNLLSKLKDEVGRKIEDSKKSIMLNNGIVMTIVGKPNSGKSTLLNRLLLEDRAIVTDIPGTTRDVIKGEIEINGIRFVIVDTAGIRETKDVVEKIGIERSLKEIQKADVILFVLDATTGFTKEDKLILRKIEGGNYIPVWNKCDEGNNFNKIFDGEIKISALNGEGLKNLENKIVSKVKNIIESGTASHVITQRQVEILERVYTHLESAVNNLNMGYEIDLISIDLRRALEELDMLIGRKFSDDLLDNIFSNFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_CLAMS
Sequence: MAKQQDVRPIIKLRSTAGTGYTYVTRKNRRNNPDRLVLKKYDPVVRTHVDFREER
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SRM1_ARATH
Sequence: MTVEEVSDGSVWSREDDIAFERALANNTDESEERWEKIAADVPGKSVEQIKEHYELLVEDVTRIESGCVPLPAYGSPEGSNGHAGDEGASSKKGGNSHAGESNQAGKSKSDQERRKGIAWTEDEHRLFLLGLDKYGKGDWRSISRNFVVTRTPTQVASHAQKYFIRLNSMNKDRRRSSIHDITSVGNADVSTPQGPITGQNNSNNNNNNNNNNSSPAVAGGGNKSAKQAVSQAPPGPPMYGTPAIGQPAVGTPVNLPAPPHMAYGVHAAPVPGSVVPGAAMNIGQMPYTMPRTPTAHR
What is the function of this protein?
Transcription activator that coordinates abscisic acid (ABA) biosynthesis and signaling-related genes via binding to the specific promoter motif 5'-(A/T)AACCAT-3'.  Represses ABA-mediated salt (e. g.  NaCl and KCl) stress tolerance.  Regulates leaf shape and promotes vegetative growth.
What are the official names of this protein?
Transcription factor SRM1, Myb-related protein SRM1, Protein SALT-RELATED MYB 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCUP_RHOCA
Sequence: MTDKTILRALKGEVLPTPPVWLMRQAGRYLPEYRATRAQAGDFLSLCYTPDLAAEVTLQPIRRYGFDAAILFADILLLPQALGLDLWFETGEGPRMSTVTSMEGVKGLKGKDDIHDKLAPVYETCKILSRELPKETTFIGFAGMPWTVATYMIAGRGSKDQAAAHKFKDTDRAAFSALIDAVTVATIEYLSKQVEAGCEVVKLFDSWAGSLKGQDFEDFAVEPARVITAEMKRRFPGLPVIAFPREAGQGYIGFAEKTGADCVAIDNSVSPDWAAENVQKGKTCVQGNLDPSYMVTGGQELVEATKKVVAAFKNGPHIFNLGHGITPEANPDNVTLLMETIRKG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_METAR
Sequence: MTGNTFGNAFRITTFGESHGPGLGVVIDGCPAGLPLTEADVQAELDKRKPGQSEVTTQRKEADMVEILSGVFEGLTTGTPIAMLVRNADARSAAYENIRNIARPGHADFGYMEKYGMRDYRGGGRSSGRETLSRVAGGAVAKKLLSLYGVEVHAHTVAIGNVRAKPATIEEIKANVWKNPVRCADLSAADAMLREVSAAREASDSVGGIVEIVATGVPAGVGTPAFDKLDACLAYALMGIGGVKAVEIGAGIASAGMRGSEMNDEFCTEDGKVRTKTNRCGGILGGISTGMPIVCRAAIKPTPSISRPQRTVNLETGAETIIEITGRHDPSIVPRAVPVAEAMVALVIVDQMISGGLINPVSAGAVDASRNR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: AAMP_BOVIN
Sequence: MESESESGAAADTPPLETLSFHGDEEIIEVVELDPGPPDPDDLVQEMEDVDFEEEEEEEGNEEGWVLEPQEGVVGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVPTGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGNSIHVLKGTEGHQGPLTCVATNQDGSLILTGSVDCQAKLVSATTGKVVGVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLSTQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAKVFCVQRPDR
What is the function of this protein?
Plays a role in angiogenesis and cell migration.  In smooth muscle cell migration, may act through the RhoA pathway.
What are the official names of this protein?
Angio-associated migratory cell protein.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm.
Protein: HIS5_BACC4
Sequence: MIAIIDYGMGNIRSVEQALKYIGAEYIVTSNKKEILRSDGVILPGVGAFPKAMDVLEERDLVCVLKEVCDIGKPLLGICLGMQLLFERSEELKDCSGLGLLPGEIRKLKVSYKIPHMGWNELRKEREFPLWNGLVDGSFVYYVHSYYADCPDEIVCGVSDYGMQVPGFVAKGNVFGAQFHPEKSGEIGMQILKNFQGVVEAWKSSQLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM49_HUMAN
Sequence: MAATMFRATLRGWRTGVQRGCGLRLLSQTQGPPDYPRFVESVDEYQFVERLLPATRIPDPPKHEHYPTPSGWQPPRDPPPNLPYFVRRSRMHNIPVYKDITHGNRQMTVIRKVEGDIWALQKDVEDFLSPLLGKTPVTQVNEVTGTLRIKGYFDQELKAWLLEKGF
What are the official names of this protein?
39S ribosomal protein L49, mitochondrial, L49mt, MRP-L49, Mitochondrial large ribosomal subunit protein mL49, Neighbor of FAU, NOF, Protein NOF1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL49 family.
Protein: RL31_MYCBO
Sequence: MKSDIHPAYEETTVVCGCGNTFQTRSTKPGGRIVVEVCSQCHPFYTGKQKILDSGGRVARFEKRYGKRKVGADKAVSTGK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ENO_MARMS
Sequence: MSQIVDIKAREVLDSRGNPTVEADVILADGSVGSACAPSGASTGSREALELRDGDKSRYLGKGVLKAVAAVNGPIRDALIGKDALAQAEIDHIMIDLDGTENKSTFGANAILAVSLAVAKAAAISKKVPLYAHIADINGTPGVYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAPNFREALRYGAEIFHALKKVLSDRGLSTAVGDEGGFAPDLSSNAEALAVIKEAVAAAGYELGKDITLAMDCAASEFYDKEANIYDLKGEGKKFTSEEFNFFLQDLTKQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDLFVTNTKILQRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEEQLGGKAPYKGRSEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: OAT_MOUSE
Sequence: MLSKLASLQTIAALRRGVHTSVASATSVATKKTEQGPPSSEYIFERESKYGAHNYHPLPVALERGKGIYMWDVEGRQYFDFLSAYGAVSQGHCHPKIIDAMKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYNKVLPMNTGVEAGETACKLARRWGYTVKGIQKYKAKIVFADGNFWGRTLSAISSSTDPTSYDGFGPFMPGFETIPYNDLPALERALQDPNVAAFMVEPIQGEAGVIVPDPGYLTGVRELCTRHQVLFIADEIQTGLARTGRWLAVDHENVRPDMVLLGKALSGGLYPVSAVLCDDEIMLTIKPGEHGSTYGGNPLGCRIAIAALEVLEEENLAENADKMGAILRKELMKLPSDVVTSVRGKGLLNAIVIRETKDCDAWKVCLRLRDNGLLAKPTHGDIIRLAPPLVIKEDEIRESVEIINKTILSF
What is the function of this protein?
Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate.
What are the official names of this protein?
Ornithine aminotransferase, mitochondrial, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PG061_VACCC
Sequence: MKVVIVTSVRSLLDASIQFQKTACRHHCNYLSMQVVKEIEEFGTINEKNLEFDTWKDVIQNDEIDALVFYRVKQISISTGVLYESMMRNRTKPISMYFVRDCLAFDGNPPSFRMTSCNINAYNRSKIKDLIILMNMKTCNKKIIGEFIIDNFGSVDALLSIVNSNVTWVTSVINNSNGRGINIRVSNNKMLTITSFRRFVNKLKMYKTTKCASQLDNLCTEMNKMDIIDKK
What are the official names of this protein?
Protein OPG061, Protein F16.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG058 family.
Protein: FZD6_HUMAN
Sequence: MEMFTFLLTCIFLPLLRGHSLFTCEPITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVPTCIEQIHVVPPCRKLCEKVYSDCKKLIDTFGIRWPEELECDRLQYCDETVPVTFDPHTEFLGPQKKTEQVQRDIGFWCPRHLKTSGGQGYKFLGIDQCAPPCPNMYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQAKAKARPELALFMIKYLMTLIVGISAVFWVGSKKTCTEWAGFFKRNRKRDPISESRRVLQESCEFFLKHNSKVKHKKKHYKPSSHKLKVISKSMGTSTGATANHGTSAVAITSHDYLGQETLTEIQTSPETSMREVKADGASTPRLREQDCGEPASPAASISRLSGEQVDGKGQAGSVSESARSEGRISPKSDITDTGLAQSNNLQVPSSSEPSSLKGSTSLLVHPVSGVRKEQGGGCHSDT
What is the function of this protein?
Receptor for Wnt proteins.  Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.  Together with FZD3, is involved in the neural tube closure and plays a role in the regulation of the establishment of planar cell polarity (PCP), particularly in the orientation of asymmetric bundles of stereocilia on the apical faces of a subset of auditory and vestibular sensory cells located in the inner ear (By similarity).
What are the official names of this protein?
Frizzled-6, Fz-6, hFz6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell surface. Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with FZD3 at the apical face of cells (By similarity). Localizes to the endoplasmic reticulum membrane in the presence of LMBR1L (By similarity).
Protein: B31K_ONYPH
Sequence: DQDDDIENVITLIETKENQTEQIKXQXXQLLQD
What are the official names of this protein?
Unknown 31.6 kDa protein from 2D-PAGE.
Protein: CLPX_LEPBP
Sequence: MTKRASQTGNSREKLHCSFCGKAQDEVRRLVAGPGVYICDECISLCNEIIAEEPQSGEKTAIVGDIPKPTEIKKILDQYVIGQEQAKKALAVAVYNHYKRIFHNERKAGDVELEKSNIMLIGPTGSGKTLLAQTLARILKVPFAIVDATALTEAGYVGEDVENIILKLIQNADNDVKRAEMGIIYIDEIDKISRKSDSASITRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEYIPVETKNILFICGGAFVGLTDIIKQRVGVKSIGFHSNEVVNDRGRKIEEGESLVHHVIPDDLMKFGLIPEFIGRLPIIATLDELTIESLKSIFTEPKNSLLKQYQKMFDIENVKLKFTESAIEAIAQTAIKRESGARGLRAIVEEIMMELMFQIPSRKDVLEVVVTDDTVLKKEAPITILKGDIEKIA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL3_SHEB5
Sequence: MAIGLIGRKVGMTRIFTEDGVSIPVTVIEVAGNRVTQVKTLETDGYRALQVTTGTKKANRITKPEAGHFAKSGVEAGRGLWEMRLVDGEGEGIEVGAELNVDIFADVAKVDVTGQSKGKGFQGGVKRWNFRTQDMTHGNSLSHRSNGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLVVVRVDVERNLLLVRGAVPGATNGDLIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: VARIA_DERVA
Sequence: NTFSDENPGFPCDCTSADAKRACGIQCACWPRGDTPGGGRRIIDGQQ
What is the function of this protein?
Potently inhibits platelet aggregation induced by ADP (IC(50)=157 nM, complete inhibition at 514 nM).  Also inhibits platelet aggregation induced by collagen and by the thrombin receptor peptide SFLLRNP.  Is a potent antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (ITGA2B/ITGB3) and the vitronectin receptor alpha-v/beta-3 (ITGAV/ITGB3).
What are the official names of this protein?
Variabilin, Anti-platelet agent, Platelet aggregation inhibitor, PAI.
What are the subcellular locations of this protein?
Secreted.
Protein: TM268_HUMAN
Sequence: MACEPQVDPGATGPLPPSSPGWSALPGGSPPGWGQELHNGQVLTVLRIDNTCAPISFDLGAAEEQLQTWGIQVPADQYRSLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVVVWANIYSTSQMFALGNHWAGMLLVTLAAVSLTLTLVLVFERHQKKANTNTDLRLAAANGALLRHRVLLGVTDTVEGCQSVIQLWFVYFDLENCVQFLSDHVQEMKTSQESLLRSRLSQLCVVMETGVSPATAEGPENLEDAPLLPGNSCPNERPLMQTELHQLVPEAEPEEMARQLLAVFGGYYIRLLVTSQLPQAMGTRHTNSPRIPCPCQLIEAYILGTGCCPFLAR
What are the official names of this protein?
Transmembrane protein 268.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ERA_STRPM
Sequence: MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: NU4LM_AVAOC
Sequence: MPPIFTNVILAFATAFLGTLIFRSHLMSSLLCLEGMMLSLFILSTLIILNMHLTVSFMMPILLLVFAACEAAIGLALLVMVSNTYGLDHIKNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL3_LACP7
Sequence: MKKAILATKIGMTQIFNENGVLTPVTVLQAGPCAVTQVKTVDNDGYAAVQVGFGDIRETLVNKPQKGHFAKAGVANKRFLKEFRFENAADYTVGQEIKVDIFTAGDKIDATGTSKGKGFQGAIKRHGLSRGPMGHGSKFHRHAGSNGAATTPGRVFKGKHMPGQMGNVKVTVQNLEVVKIDVDNNLILVKGAVPGPKKAMIMLKETVKSGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MIAB_CELJU
Sequence: MSATQTPTKKLYIKTHGCQMNEYDSNRMRDLLGESHNMVATENPEEADVILINTCSIREKAQEKLFHELGRWKNLKKQNPELIIGVGGCVASQEGAAIAERAPYVDLIFGPQTLHRLPEMMETKKSNGVVVVDISFPEIEKFDKLPQPDADGVSAFVSIMEGCSKYCTFCVVPYTRGEEVSRPVADVMAEVIHLAKQGVREVNLLGQNVNAYRGAAADGTIVDLAELITYIAAVDGIDRIRFTTSHPVEFTDALIEVYNQVPELVSHLHLPVQSGSDRILMAMKRGHTVLEYKSKLRRIKKNRPNISFSSDFIIGFPGETDADFEATMKLIHDMEFDTSFSFIYSPRPGTPAADLPDDTPEEVKKQRLAILQDRITQQAMAISRRMVGNTERILVSGYSKKDPGQLSGRTENNRVVNFRCDNPALIGKFADVLIEEALPNSLRGSLIASELDQDWH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_NYMAL
Sequence: MNVLPCSINTLKGLYEISGVEVGQHFYWQIGGFQVHAQVLITSWVVIAILLGSAAIAVRNPQTIPTDGQNFFEYVLEFIRDVSKTQIGEEEYGPWVPFIGTLFLFIFVSNWSGALLPWRIIQLPHGELAAPTNDINTTVALALPTSVAYFYAGLTKKGLGYFGKYIQPTPILLPINVLEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVIPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y2365_ARCFU
Sequence: MFGEMSGEYGELGVDKERLKEVGIELDKSKRSGVYLQEDQDAKTFSSFFEGVEVMSIKQAMEKYDWVKDYFWKILRKDQDEFTRMADTEDVNGYFIRSLPGAKVEIPVEACLYLKKVEKQRVHNIVIAEEGSELNIISGCTSHPGVAGMHIGISEFFVKKNAKLSFTMIHSWDTTIEVRPRTAIKVEEGGTFISNYILLNPVKLVQTYPTAYVEKDATAIFNSVIVALEGSVVDSGSRAVLMGENSRAEIISRTISKGGKIIARGHIIGDAPEVKGHLECKGLMLSESGLIDAIPELEARYPNVELSHEAAIGKIAEEGIFYLMSRGLSRDEAISAIVRGFMEIEIKGLPEALQEAIRRTIEMAERDLL
What are the official names of this protein?
UPF0051 protein AF_2365.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.