PharMolix/UniProtQA huggingface dataset:
Protein: PSAJ_BARVE
Sequence: MRDLKTYLSVAPVLSTLWFASLAGLLIEINRLFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUON_CAMLR
Sequence: MSGFSLEKFNFVLLFPVLSLLFWAIVLLLLDAFKKLSRNFYIGASIIALFSTLCFLLIYNGFVLDNSHAFFDLFVSDNYAIFAQIVILVFSMLYLLMDKDEQKAEFFSLFLFMIASLILMISSTNLIVIFLALEGSSLALYTLIALRGTHNAISSSIKYFTLAAVGAGFFVFACAFVYLKTKSLDLDNLLHSEYISDPILLCAGVMFLVIVGVKLSIAPFHFWLKDVYYGVHTNFIAFISIVPKIAMIIVVLRIFSALGGGVKFEYIVALLAIFSMLAVSIVALIQKDVKKMLAYSSITHSSFILAVIVSSMSVSSQGDGTSYLLSIFALFVYWISFAFANYGIFLILSLFQKSSFESFSGLFDQRPVLSIMLAIFILCIAGIPPFGIFWGKILILASILNSGYYALVFAVALSSMIMLYAYLKILIYVFFKKAQIVESANLDVKQKIILCLCLIGSVSCVFLLL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARNE_ECO7I
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AP2E_HUMAN
Sequence: MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSVGSGHGETKASEKDAKHRK
What is the function of this protein?
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.  AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development.  They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.  AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity).
What are the official names of this protein?
Transcription factor AP-2-epsilon, AP2-epsilon, Activating enhancer-binding protein 2-epsilon.
What is the protein family that this protein belongs to?
Belongs to the AP-2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIMCH_DICDI
Sequence: MIKANWTSTSAFNLELALDESRDWIERVINQKFPSDFQSSLRDGIFLCKLINQIQPNSVPKYNQSPSTDFAKRENIQLFIKSAKHSMGLRDTQLFESQDLFESIRIRNIAITLYWLGRAARASQTYKGPQLDLLKFQGMNCSACKKAITNNDYLTTMTQQFHTSCAVCCSCSCKLDPKKKFYQESNNFWCENCMLGATNLGGSNNSSGGKNKSNNNNNNKCSGCFGSLEKGYVPDENDKEKKYCTSCICDLCHDPLIGNFQVKDGKKVCDSCSCKSCGKSLEDGYYEEGISKYCEPCAKDRNKPKQVMDKDGHDHHHHNHNKPTTTTTTTNSNSPLAKKKSDSCKMCDKPVDNKTKKYGDDRDKYCTPHEKDGTCGKCNGELVGSAISVMDKNFHPQCFKCDSCNKNLNQNDQIKKSPTTGNPLCGPCSSNNNKSSKNCHDCKKPISGSSVEALDRPYHPNCLKCYSCSKNLKEDFTEVDNEPFCNPCASQLNQYTSGNQKQPKQGGSPFITSGWLDSDRCVVCVKPLNGEVAKIFDSFYHKGCFKCTDKSCNAPLLTGYFPHDKKPYCQKCSIKIQQSTTTDHCAKCSKPIIEGSILKVAGKVYHKSCYDNEKHTSSSSSSSSVNCFKCKSQITGTQFVRLDQKDYCMKCSPSASSSTTVTHGERLNYGMTVDPRSGKRVFNTSK
What is the function of this protein?
Involved in the regulation of phagocytosis.  May repress rab21.
What are the official names of this protein?
Calponin homology and LIM domain-containing protein, CH-LIM.
Protein: LEUC_BURA4
Sequence: MAQTLYDKLWNTHVVHTEDDGTALLYIDRQLLHEVTSPQAFEGLNVAHRPVWRISANLAVSDHNVPTTDRSHGIADPVSKLQVDTLDANCDAFGITQFKMNDVRQGIVHIIGPEQGATLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLQKKSKNMLVKVEGALPRGCTAKDIVLAIIGRIGTAGGTGYAIEFGGSTIRALTMEGRMTVCNMAIEAGARAGMVAVDDTTIDYLKGRPFVPTGAEWDQAVEYWREFKSDEGAQFDRVVELNAAEIVPQVTWGTSPEMVTSIDGRVPDPEREKDPVKRDAMERALAYMALEPNTPMESIKVDKIFIGSCTNARIEDIRAAAYVVKKLNRRIASNVRLAMVVPGSGLVKAQAEREGLDKVFTDAGFEWREPGCSMCLAMNADRLDPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAIEGHFVDIRQLG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: YOOC_SCHPO
Sequence: MARDVDNKQNAKRISRDEDEDEFAGESMVGRTLDNPFLGEDEFEDIFGSESQYISSSGQNSTNPFLADTRIENSPLGSESKANQLNKQGTNVNHIEIPLRDFNDPTQPESFLPPPKNTFTSRIKKIKNLFKKEKKQVKPEDLGPRQIILNDYSANHFLHNAVSTCKYSAFTFLPKFLKEQFSKYANLFFLFTAVVQQIPGITPVNRYTTIGPMLIVLSVSGIKEIMEDIKRKKQDQELNESPCYVLQGTGFVEKQWKDVVVGDIVKIVSETFFPADLVLLSSSEPEGLCYIETANLDGETNLKIKQALPETAGLLKPVELGQLSGEVKSEQPNNNLYTFDATLKLLPSDRELPLSPDQLLLRGAQLRNTPWVYGIVVFTGHESKLMKNTTETPIKRTSVEKQVNSQILFLLCIFVFLCFASSLGALIHRSVYGSALSYVKYTSNRAGMFFKGLLTFWILYSNLVPISLFVTFELVRYIQAQLISSDLDMYNEETDTPAACRTSSLVEELGQVGYIFSDKTGTLTRNQMEFRQCTIAGVAYADVIPEDRQFTSEDLDSDMYIYDFDTLKENLKHSENASLIHQFLLVLSICHTVIPEYDESTNSIKYQASSPDEGALVKGAASIGYKFLARKPHLVTVSIFGKDESYELLHICEFNSTRKRMSIVFRCPDGKIRLYVKGADTVIMERLASDNPYLQTTIHHLEDYATVGLRTLCIAMREVPEDEYQRWSTVFETAASSLVDRAQKLMDAAEEIEKDLILLGATAIEDRLQDGVPDTISTLQTAGIKIWVLTGDRQETAINIGMSCKLIDEDMGLVIVNEETKEATAESVMAKLSSIYRNEATTGNVESMALVIDGVSLTYALDFSLERRFFELASLCRAVICCRVSPLQKALIVKMVKRNTGEVLLAIGDGANDVPMIQAAHVGVGISGMEGLQAVRSSDFSISQFCYLKKLLLVHGSWCYQRLSKLILYSFYKNIALYMTQFWYAFCNAFSGQVIFESWSISLYNVLFTVLPPVVIGIFDQFVSAGQLFQYPQLYQLGQRSEFFNLKRFWSWITNGFYHSLLLFLCSIAVFYYDGPNKDGLASGHWVWGTTLYAAILATVLGKAALISNHWTQYTVIATLGSFLLWIVFMPIYAVAAPAIGFSKEYYGIIPHLYGNLKFWASLLVLPTIALMRDFVWKYSSRMYYPEEYHYVQEIQKYNVTDYRPRIVGFHKAIRKIRQMQRMRKQRGYAFSQGEEDQSRILDAYDTTHTRGAYGEMR
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids.
What are the official names of this protein?
Probable phospholipid-transporting ATPase C887.12.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: PG039_VAR67
Sequence: MDLSRINTRKSKQLKSFLSSKDTFKADVHGHSALYYAIADNNMRLVCTLLNAGALKNLLENEFPLH
What are the official names of this protein?
Truncated interferon antagonist OPG039.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG039 family.
Protein: RS19_FRATH
Sequence: MPRSLKKGPFVDHHLLKKVFEAQESNSKKPIKTWSRRSMIVPDMIGLTIAVHNGQQHVPVLMTEEMVGHKLGEFVVTRNYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SSRP_DESVH
Sequence: MSKKAPGANVIAQNKKARHIYELSDNHEAGISLTGSEVKSLRAGHVNFRDSYVDFRNGEAFLVGLHIAPYDNAGYAQHDPDRDRKLLLHAHEIENLARSVEQKGYTVVPTKLYFARGKVKVDIAVGRGKKLHDQREDLKRRAEDRDTQRELARF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RUVB_THET2
Sequence: MRRTGIRLSWRSVDDLALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDLAAILANSLEEGDILFIDEIHRLSRQAEEHLYPAMEDFVMDIVIGQGPAARTIRLELPRFTLIGATTRPGLITAPLLSRFGIVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGRRSRGTMRVAKRLFRRVRDFAQVAGEEVITRERALEALAALGLDELGLEKRDREILEVLILRFGGGPVGLATLATALSEDPGTLEEVHEPYLIRQGLLKRTPRGRVATELAYRHLGYPPPVGPLLEP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GCST_BURP6
Sequence: MTVLKTTPLHAAHRALNARMVDFGGWDMPVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHAIANNVAKLQTPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTAEKDIAWFNQLNEQGGFGLTIAPRRDFAIVAAQGPNARAKVWDTVPCARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEIIVPATHVEALWNALAERGVRPCGLGARDTLRLEAGMNLYGQDMDESVSPLDAGLAWTVDLSAPRAFVGRDALEAHGSRAAFVGLILQKENGRAGGVLRAHQKVATPHGEGEITSGTFSPSMQESIAFARVPKDVAIGDTVHVQIRDKQLPARVVKLPFVRNGKVLAA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: SIN1_MOUSE
Sequence: MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKTHPPSVPGDSGSEVQGSSGETQGYIYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQELKSLFEKKSLKEKPPSSGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRKGSQKISGPQYRLEKQSEPNIAVDLESTLESQNAWEFCLVRENSSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDCDLLCACDLAEEKSPSHAVFKLTYLSSHDYKHLYFESDAATVSEIVLKVNYILESRASTARADYLAQKQRKLNRRTSFSFQKEKKSGQQ
What is the function of this protein?
Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals.  mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive.  mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.  mTORC2 promotes the serum-induced formation of stress-fibers or F-actin.  mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation.  mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'.  mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'.  Within mTORC2, MAPKAP1 is required for complex formation and mTORC2 kinase activity.  MAPKAP1 inhibits MAP3K2 by preventing its dimerization and autophosphorylation.  Inhibits HRAS and KRAS signaling.  Enhances osmotic stress-induced phosphorylation of ATF2 and ATF2-mediated transcription.  Isoform 1 is involved in ciliogenesis, regulates cilia length through its interaction with CCDC28B independently of mTORC2 complex.
What are the official names of this protein?
Target of rapamycin complex 2 subunit MAPKAP1, TORC2 subunit MAPKAP1, Mitogen-activated protein kinase 2-associated protein 1, Stress-activated map kinase-interacting protein 1, SAPK-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the SIN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasmic vesicle. Nucleus.
Protein: 169L_IIV6
Sequence: MFSNISNQKLVLFFTIILIALCPFVYYLWDNEILGIGNWGRKRKDTFEDKNCSTEIEHAIEEHKRKNKEKKEAKEKRLAPGRVKISTYDVNNENYLLGDVNDELQPNIPGYLTKETAYPFDCEPDDRSNRWL
What are the official names of this protein?
Uncharacterized protein 169L.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL9_AERS4
Sequence: MQVILLDKIAKLGGLGDQVAVKAGYARNYLIPQGKAVMATKANIETFDARRAELEAKLAAGKAAAEERAAKLGELAAVVIASKAGDEGKLFGSIGTRDVADAITAAGVAVAKSEVRMGNVLRNTGEYEVVVQLHADVKATVQVQVVAL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RS18_BORBU
Sequence: MYKDRDTNQRDSRFENQQDGFKKNSNFRFFKRKSCKFCDSGKHPDYKDFDFLKKFITEQGKILPKRITGTSAKHQRRLALEIKRARYMALLPFVKK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MUA1_XENLA
Sequence: MKHIILCIHFLLMVVGLGQAQDCSVAPNMRVNCGYPTVTEADCRAVGCCFDSSILNTKWCFYNATAGPIKKLECSGDPTKRIDCGFPRITEKQCILRGCCFDSSISGVKWCYARTVITTPAPDTTTASTTAETTTVPTTPETTTVPTTPETTTVPTTPETTTVPTTPETTTVPTTPETTTVPTTPETTTVPTTPETTTVPTTPETTTVPTTPETTTVPTTPETTTVPTTPETTTASTTAETTTVPTTPETTTEPTTTPTTDTTPPTLPPTPETTTETTTETTTETTTETTTETTTETTTAPPPECAADRVDCGYSGITQADCEGKGCIFDSTIPETKWCFYTEAEAPARKAECTVDPSVRTDCGYPGITDKECREKGCCYDECIPDVIWCFEKAVPVVNS
What is the function of this protein?
Could be involved in defense against microbial infections.  Protects the epithelia from external environment.
What are the official names of this protein?
Integumentary mucin A.1, FIM-A.1, Preprospasmolysin.
What are the subcellular locations of this protein?
Secreted.
Protein: REX_STAAM
Sequence: MSDQVKIPRATLKRLPLYYRFVSSLKSKGIDRVNSKAISDALQIDSATIRRDFSYFGELGKKGYGYNIDSLLDFFKSELSESDMIKIAIVGVGNLGKALLTYNFSIHDDMTITEAFDVKEDVIGQKIGNVIVKDNDELITTLKKEEIDVVILTTPERVAQKVADELVQAGVKGILNFTPGRINTPSDVQVHQIDLGIELQSLLFFMKNYSE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_ALTMC
Sequence: MTIIRKKHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTSTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGMYYGSYNMIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDFLGVLILLMGLMILVLFFPDVLGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALLPLLHTSKQRGLTFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQTASIAYFTIIVILMPMAGMIENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RUVB_LEGPH
Sequence: MLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDYSEVKGNGIITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GSA_THEAB
Sequence: MFEIAKKYMPGGVNSPVRAFKSVEMEPIFVKSAKKSKLIDINNKEYIDYIQSWGALILGHAHEEVVEEIKKQAELGTSYGLCHELEVEMARLIVKHIPSVEMVRMVNSGTEAVMSAIRLARAYTNRELIVKFEGCYHGHSDGLLVKAGSGALTFGTPSSKGVTEKIVSNTLVARYNDIESVKELFDKYGENIACVIVEPVAGNMGVVLPKQGFLEGLREITKEYGSLLIFDEVITGFRVSINGAQGYYNVFPDITTLGKIIGGGLPVGAYGGRKEIMELISPQGPVYQAGTLSGNPLTLAAGIKTIKIIENDPDFYSKLDELGKYFEEGIVSALGDFDVKINRIKSMLSFFFSKQEVDSYEKVINSDVEIYKKLFKCLFENGILLPPSPFESLFISSSHTKEDIEKTVYYFEKFSKKLKEGKV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1628_METJA
Sequence: MFVDEVINNLKGNEFLNTTLLTKSNKNKLYYAVKQPDGNIKVVLPFVFENKNFLKLSEYKDGIEGATQRVIEEIKQEIIKKKRFLPLAGYFGRIYKALYEPLTVVNCNLNLGYDLWKVDKYNYIEGDKIYLMLRMIFKEKDSKEIVKQINELCNDLDKFIKKIPIDLLIDEAKNIINQKYLRDKLDELGLVCFIANNSKPARKYTEVRRHYRIAGPKDVNIPFECPEELEPIEIELKYGKKVKGLGIKKKEIFIITGRNAQGKTTLLQAIDSGRDDHLIGDGREFIITTKSLSKASTGSMEMSGQDISLFFQKLPPGIKGSPKAVYGTASGSMYMAYQIQRAIKNKTKLILIDEDNSAVNLLVSGVLSKWFEGVKSLAEIIMEDREKLGDSSFIIVTSSLDLLTALGDRAIYLEDHKAKYLDLTYFREELGRYYLELASKFIGVKIRE
What are the official names of this protein?
Uncharacterized protein MJ1628.
Protein: ARNA_PROMH
Sequence: MKAIVFAYHDIGCVGLKALEKAGFDIQAVFTHTDDPNENHFFSSVARVSAEMGLTVFAPENVNHPLWIERIREMKPDVIFSFYYRHMLSDEILNLAPKGAFNLHGSLLPKYRGRAPINWAIVNGETETGVTLHKMTAKADAGDIVAQEKVTIEDTDTSLILHEKVREAAAKLMAHTLPHIASGNYSTTAQDESQATYYGRRCADDGLIDWNADAKTVHNLVRAVTEPYPGAFTFLGERKMIIWRARPVADNQGKRPGTVISTEPLVIACAKGAIEVITGQSENGLYVQGSRLATEMGIVTDVRVGPKATAQVKRRQRVLILGVNGFIGNHLTERLLKDGNYDIYGMDIGSSAIERFIGNPRFHFIEGDVSIHTEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRYCVKYNKRIIFPSTSEVYGMCDDKEFDEDNSRLIVGPINKQRWIYSVSKQLLDRVIWAYGAKEGLKFTLFRPFNWMGPRLDNLNSARIGSSRAITQLILNLVEGSPIKLVDGGEQKRCFTDINDGIEALFRIIENRDNKCDGQIINIGNPTNEASIRELAEMLLDCFEKHELRGHFPPFAGFKKIESSSYYGKGYQDVEHRKPSIKNAERLLDWKPTIETRQTVEETLDFFLRGAVEELGNK
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: RIMO_SYNR3
Sequence: MPAGHGQTAMTREQQPPRFTLNCWADAAMASTATTARPTVAFAHLGCEKNRVDTEHMLGLLAQAGYGVSADEADAQVVVVNTCSFIQDARAESVRTLVDLAEQGKQIVIAGCLAQHFQEELLESLPEARAIVGTGDYQHIVEVLEQVEAGERVNRVSQVPTFVADENLPRYRTTSEAVAYLKVAEGCDYRCAFCIIPKLRGDQRSRPIESIVAEAQQLAAQGVKELILISQITTNYGLDLYGKPQLAELLRALGEVEIPWIRVHYAYPTGLTPEVLAAYREVPNVLPYLDLPLQHSHPEVLRAMNRPWQEGVNGQLLQRIREQLPDAVLRTTFIVGYPGETEEQFEHLLEFVQEQRFDHVGVFCFSPEDGTPAADLPNAVPAEVAEARRGRLMEAQQAISAERNGAWVGRIVDVLVEQENPSSGELIGRCLRFAPDVDGEVRIRAGSHGAAASAGTMVPVRITAADIYDLEGEVVGAQEMVDAVRHS
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1421_CORA7
Sequence: MAGHSKWATTKHKKAANDAKRGKEFAKLIKNIEVAARTGGGDPAANPTLDDMIKKAKKASVPNDNIERARKRGSGEEAGGADWETVMYEGYGPNGVAMLIECLTDNRNRAATDVRTAMTKNGGNLGESGSVAYMFSRTGLVMVEKGELSEDDILIAVLEAGAEEVNDNGEKFEITCAPGDVPAVREALVAADIEVDDTDTDFRASVEVPLQADDARKIFRLIDALEDSDDVQNVYTNMDLSEEVLAELGED
What are the official names of this protein?
Probable transcriptional regulatory protein cauri_1421.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.