PharMolix/UniProtQA huggingface dataset:
Protein: ASK1_SCHPO
Sequence: MNNLEQLERLEQSITLALYEIDANFSKCHRTVTTKILPIVEKYAKNCNTIWDSSKFWKQFFEASANVSLSGVEEPVPVESNPSDQDVMSNSTEADLQLHTKNEHLEKRHSFVGKSDFPDAAVQGDNTKNEDFVQSTPKKMDVSLEDISLDDAALTPIPARMQTPLRKPENNPHTGRSALLHRVLDTNWQVQVTPREPKNLQSQEVMDIDSSPFVSPSPISMKMDMPSLNDRNSSHALSLFAEFEHESYDSINPSGMSPPKTIQFSPHTMGVGSSQQANERSLSLQRKLETLNDSNDSFVKEEDSWEL
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.  Plays a role in meiosis.
What are the official names of this protein?
DASH complex subunit ask1, Associated with spindles and kinetochores protein 1, Meiotically up-regulated gene 181 protein, Outer kinetochore protein ask1.
What is the protein family that this protein belongs to?
Belongs to the DASH complex ASK1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore. Kinetochore association occurs only during mitosis.
Protein: MTNC_CITK8
Sequence: MIRAIVTDIEGTTSDIRFVHNVLFPYARERLAAFVTARQYAEPVKSILDNLRNEIARPDASTAELIETLFTFMDEDRKSTALKALQGIIWHDGYVNGDFTGHLYPDVLPALEKWKAQGIDLYVYSSGSVAAQKLLFGYSDEGDITHLFSGYFDTHIGAKRETQSYRNIASYIGVAPSQILFLSDVYQELDAAEEAGLRTLQLIRGEGDGASRHHQVHQFDDINPEQILS
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: TATA_SHESH
Sequence: MGGISIWQLLIVALIVVLLFGTKKLRSLGGDLGGAVKGFKSAMSSEEEKKAIEDSASEKTAQTEEKKTESKDKDKEQV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PP16A_CUCMA
Sequence: MGMGMMEVHLISGKGLQAHDPLNKPIDPYAEINFKGQERMSKVAKNAGPNPLWDEKFKFLAEYPGSGGDFHILFKVMDHDAIDGDDYIGDVKIDVKNLLAEGVRKGKSEMPPRMYHVLAHKIHFKGEIEVGVSFKLQGGGGCGGCYPWEN
What is the function of this protein?
Binds to both sense and antisense RNA.  Interacts with mesophyll plasmodesmata to mediate its own cell-to-cell transport and potentiate RNA trafficking.
What are the official names of this protein?
16 kDa phloem protein 1.
Protein: NRDR_BIFLO
Sequence: MHCPFCQNPDTKVIDTRISDDGHSIRRRRVCPKCSKRFTTVETSMLLVTKRSGGVEPFSRDKVISGVRKACQGRPVREEDLKLLGQKVEEDLRSRGLAEVTSDEVGKAILKPLRDLDVVAYLRFASVYQNFAGLEDFQSAIDGLRE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MPK_PEA
Sequence: MEGGGGAPAADAVMEDAAPQQQEPQQQAAMGIENIPATLSHGGRFIQYNIFGNIFEVTAKYRPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLVRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEADLGFLNENAKRYIRQLPLYRRQSFQEKFPHVHPEAIDLVEKMLTFDPRQRITVENALAHPYLTSLHDISDEPVCTTPFSFDFEQHALTEEQMKELIYREALAFNPEYQQ
What are the official names of this protein?
Mitogen-activated protein kinase homolog D5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: EFMT1_XENLA
Sequence: MEGSDDDDGVPQLSSHALAALQEFYAEQQQREAQKLGPDHEKFSVGSVEEDWQLSQFWYSDETALSLAKEAIEVCGENGRIACISAPSIYQKLRGLAGESVYIRLLEYDNRFAVYGDDFVFYDYNEPLKLPESLEPSSFDIVIADPPYLSEECLQNTAQTIKHLSRGKIILCTGAVMEDLAAQKLGLKKCKFIPEHTRNLANEFRCYSNYELALDKQGLA
What is the function of this protein?
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
What are the official names of this protein?
EEF1A lysine methyltransferase 1, N(6)-adenine-specific DNA methyltransferase 2, Protein-lysine N-methyltransferase n6amt2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y919_MYCBO
Sequence: MRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLHVGALAVLSQPDNGTGRYLRKVFSAAVARQQVAPWWRRRPHRSLTSLGQWSWRTETEVDLDYHVRLSALPPRAGTAELWALVSELHAGMLDRSRPLWQVDLIEGLPGGRCAVYVKVHHALADGVSVMRLLQRIVTADPHQRQMPTLWEVPAQASVAKHTAPRGSSRPLTLAKGVLGQARGVPGMVRVVADTTWRAAQCRSGPLTLAAPHTPLNEPIAGARSVAGCSFPIERLRQVAEHADATINDVVLAMCGGALRAYLISRGALPGAPLIAMVPVSLRDTAVIDVFGQGPGNKIGTLMCSLATHLASPVERLSAIRASMRDGKAAIAGRSRNQALAMSALGAAPLALAMALGRVPAPLRPPNVTISNVPGPQGALYWNGARLDALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLAHELELLVGVSEAGPGTRLRRIAGRR
What are the official names of this protein?
Putative diacyglycerol O-acyltransferase Mb0919, Putative triacylglycerol synthase Mb0919.
What is the protein family that this protein belongs to?
Belongs to the long-chain O-acyltransferase family.
Protein: HIS6_MAGMM
Sequence: MMAKRIIPCLDVKAGRVVKGVQFEGLVDAGDPVEAAKRYDEEGADELTFLDITATHEDRGIMEDVVRRTAEQVFIPLTVGGGIRTNDDIRRMLVAGADKCSINSAAVKRPEFVREAAEQFGSQCVVVAIDAKCVEHDKHGRPIRWEIFTHGGRQPTGIDALEWAHRMESFGSGEILLTSMDKDGTKSGYALEMTRAISDAVTIPVIASGGVGEPKHLLEGLRQGGADAVLAASIFHFREYTIPQVKRYLRDNHIAVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_MYCMS
Sequence: MQVKKIKKRKKVNFFQKNNIKYIDYKDIELLKKFISPNGQILPRRITGTSPKDQRQLALAIKRARQMALLPYVIE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MAD1_ASHGO
Sequence: MSQTGDSSSFVEEPASPEARQRELERQVLGLEYRLRTEHSEAEMARLALERELAGMQGKYKQCMGELEAALADTRYLYEQNAALEARARAADEDAGGAAAAERAAAAEERARAAEARARELEEALQAARGEAAAAGRAAAGAAAGAAAAEQSGLLRKYEAEIERQMGELRALAERLAEREDEVAGLKAQRVLQAHRSYSAEEVEELGVLRRTLQEQLALSKELERANLEQANELKRLRQRSESQQFLQLENSKLRARLEKTDALRQQLDDLQLENVQLQEKLTKWEVYQADGSSPENVLHEMALAKQERLALVEQVGKLQLDLNNMKILNDELALERNQLLDLNKKYESSILNLKKLNYEIEQQKLLSFEECKLLRQQLDDLSEVDKDHTPDTRDRKKIQTLVDTYKNQTEDLTNELKKLNEQLLERSDLDGNPRKRRKASDDLAFNYSQRLNELQLRNKDLERRLANSDENASLLEEKLRKLQSLNEKKIRILQLRNNPLLKDQFVKQKQLTLLKQENLELAQQLDAQQGLEAVPRSVYERQQYDIQLLEDELFSINKRTTRLKEMFNRKSLEFIDAVNSLLGFKLEFQVGGKVKMIPCFKTDRYLIADLQTNTLKSNLDKVMPEWDAMLAEYVGKRQQLPCFLAKIMLLLAESSSSQ
What is the function of this protein?
Central component of the spindle assembly checkpoint.
What are the official names of this protein?
Spindle assembly checkpoint component MAD1, Mitotic arrest deficient protein 1.
What is the protein family that this protein belongs to?
Belongs to the MAD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIM54_CANAL
Sequence: MPDANEVKPKKGWSNPALRMMGIPRISLPSRNWMIFWTVVTTIGGGIAYDKYEQKQMRKKWMDAVKQFGEVSYGANEIPRKLSIFIAPPPNDFLDESLKLFRKFIKPVLNAGVVDFEIFSESRQGDIRASVAEKIRELRRKQLVEETPKKNESNGNQDNDEEELKSRSDLYKAKDVLGLYKVFPADINVKSEDAIDDSSAGGIICVGRGAYKEYLSGVHEGLLGPLEKPQSVIDEETKLAEEKKKEKEENPDKDDDNDEEQSNLKPVPLRYIKPEDYANAQLAPELDLSTVVKDDKGVPVFFEQPVYTFPLPNLVGFTNIPRKIYRYFTKRFLVDDFGERTATIVNNKSRPFVYKDVLMAKEEEMDWPKKWVEKGKERNSEWVQELEHDERVTSRMKVFE
What is the function of this protein?
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM54.
What is the protein family that this protein belongs to?
Belongs to the TIM54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: THIG_ALKMQ
Sequence: MEGFNIGGKSLKSRLLVGTGKFASYDLMKQAIEGCGTQVVTMALRRVNLDHKEDNILEYIPKDTILLPNTSGARNAEEAIRIARLSRAMGCGDWVKIEVISDQKYLLPDNEETVKATEVLAKEGFIVLPYMNPDLMIAKRLESVGAAAVMPLGSPIGTNKGLQTKEMIRILIEEIKVPIIVDAGIGKPSQAAEAMEMGAEAVLVNTAIATAQNPVKMAKAFELAVRAGRLAFNGVTAPQAKVARASSPLTGFLHEGEA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF2_LOBMA
Sequence: MKGHQFKSWIFELREIVREIKNSHYFLDSWTQFNSVGSFIHIFFHQERFRKLLDPRIFSILLLRNSQGSTSNRYFTIKGVVLFVVAALLYRINNRNMVESKNLYLKGLLPIPMNSIGPRNDTSEESFGSSNINRLIVSLLYLTKGKKISESCFRDPKESTWVLPITQKFIMPESNWSSRWWRNWIGKKRDFCCKISNETVAGIYISFKEKDFKYLEFLFVYYMDDPIRKGHDWELFDRLSPSKRRNIINLNSGQLFEILVKDWICYLMFAFREKIPIEVEGFFKQQGAGSTIQSNDIEPVSHLFSRNKWAISLQNCAQFHMWQFHQDLFVSWGKNPHESDFLRKISRENWIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSSFVQVTDSSQLNGSSDQFIDPFDSISNEDSEYHTLINQREIQQLKERSILLDPSFIQTEGREIESDRFPKYLSGYSSMPRLFTEREKRMNNHLLPEESEEFLGNPTRAIRSFFSDRWSELHLGSNPTERSTRDQKLLKKEQDVSFVPSRRSENKEIVNIFKIITYLQNTVSIHPISSDLGCDMVPKDELDMDSSNKISFLNKNPFFDLFHLFHERKRGGYTLRHDFESEERFQEMADLFTLSITEPDLVYHKGFAFSIDSYGLDQRQFLKEVFNSRDESKKKSLLVLPPIFYEENESFYRRIRKNWVRISCGNYLEDPKPKRVVFASNNIMEAVNQYRLIRNLIQIQFQYSPYGYIRNVLNRFFLMKRPDRNFEYGIQRDLIGNDTLNHRTIMKDTINQHLSNLKKSQKKRFDPLIFLSRTERSINRDPNAYRYKWSNGSKNFQEHLEHFVSERKSRFQVVFDRLCINQYSIDWSEVIDKKDLSKSLRFFLSKLLRFFLSKLLLFLSKLLLFLSNSLPFFFVSFENIPIHRSEIHIYELKGPNDQLCNQLLESIGLRIVHLKKLKPFLLDDHNTSQESEFLINGGTISPFLFNKIPKWMIDSFHTRKNRRKSFDNTDSYFSIVSHDQDNWLNPVKPFQRSSLISSFSKANRLRFLNNPHHFCFYCNKRFPFYVEKARLNNSDFTYGQFLTILFIHNKIFSSCGGKKKHAFLERDTISPSSIESQVSNIFISNDFPQSGDERYNLYKSFHFPIRSDPLVRRAIYSIADISGTPLIEGQRVNFERTYCQTLSDMNLSDSEEKSLHQYLNFNSNMGLIHTPCSEKYLQRKKRSLCLKKCVDKGQMDRTFQRDSAFSTLSKWNLFQTYMPWFFTSTGYKYLNLIFLDTFSDLLRILSSSQKFVSIFHDIMHGLDISWRILQKKLCLPQRNLISEISSKSLHNLLLSEEMIHPNNESSLISTHLRSPNVREVLYSILFLLLVAGYIVRTHLLFVSRAYSELQTEFEKIKSLMIPSYMIELRKLLDRYPTSELNSFWLKNLFLVALEQLGDCLEEIRGSGGNMLWGGDPAYGVKSIRSKKKDLKINFIDIIDLISIIPNPINRITFSRNTRHLSHTSKDIYSLIRKRKNVSGDWIDDKIESWVANSDSIDDKEREFLVQFSTLRAEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGTIYLRYLVDIHKKSLMNYEFNTSCLAERRIFLAHYQTITYSQTSRGANSFHFPSHGKPFSLRLALSPSRSILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFFIDDIDIDDSDDIDASNDIDRELDTELELLTMMNALTMDMMSEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNYLALGLLVNSLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFESITMGSSARDLVALTNEALSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLISNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKKFTILLYLLSCSAGLVAQDLWSLPGPDEKNRITSYGFIENDSDLVHGLLEVQGALVGSSRTEKDCSQFDNDRVTLLFRSEPRDPLYMMQDGSCSIVDQRFLYEKYESEFEEGEGEGVLDPQQIEEDLFNHIVWAPRIWRPRGFLFDCIERPNELGFPYLAGSFRGKQIIYDEKYELQENDSEFLQSGTMQYQRRDRSSKEQGFFRISQFIWDPADPLFFLFKDQPFVSVFSHREFFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLIQRQRWLRTNSSLSNGFFRSNTLSESYQYLSNLFLSNGTLLDRMTKTLLKKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CNPY4_DANRE
Sequence: MEMFTVFLFYMFSLVLANQEERLPNKCEVCKLLTVELQDALDKTGRSKEVVELGEVLDTGKRRRKIKYNTSEMRLTEAMDNICERILQYKVHAERPGSLRYAKGTSQTMNTLKNLVEKGVKVELGVPYELWDEPTVEVAELKRQCETMLEEHEEVVEDWYFHHQDKGLERFFCEAHVLKDSDQECLTEIWKGDMGMKGSEEESEGKDGKETHDAGEL
What are the official names of this protein?
Protein canopy 4.
What is the protein family that this protein belongs to?
Belongs to the canopy family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMN_AROAE
Sequence: MLTPVNLLDFDVDGLVTWFAERGEKPFRARQVMRWMHRFGETDFGNMTDVAKSLRAKLAEEACIRAPRAIRDAVSVDGTRKWLLDVGSANAVEAVFIPETNRGTLCISSQAGCALDCAFCSTGKQGFNRNLSAAEIIGQLWLANRLLGGSASPAGSKDGDGGPDHASRATKLDHRAADAKGVQSDSWRSSDPEEDHNGRVISNVVMMGMGEPLANFDNVVTALRLMLDDHAYGLSRRRVTVSTSGIVPAMDRLRDECPVALAVSLHAPDDALRDRLVPINRKYPLRELMAACQRYLERAPRDFVTFEYVMLDDVNDSDAHARALVELVRDVPCKFNLIPFNPFPNSGFDRSPAERIRRFAAILIDAGIVTTTRKTRGDDVNAACGQLAGQVQDRSRRTVRLVKPMEGR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCG3A_HUMAN
Sequence: MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITITQGLAVSTISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKTNIRSSTRDWKDHKFKWRKDPQDK
What is the function of this protein?
(Microbial infection) Involved in Dengue virus pathogenesis via antibody-dependent enhancement (ADE) mechanism.  Secondary infection with Dengue virus triggers elevated levels of afucosylated non-neutralizing IgG1s with reactivity to viral envelope/E protein.  Viral antigen-IgG1 complexes bind with high affinity to FCGR3A, facilitating virus entry in myeloid cells and subsequent viral replication.
What are the official names of this protein?
Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted. Note=Exists also as a soluble receptor.
Protein: MRAY_STAA8
Sequence: MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFATISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGVH
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3122_ARATH
Sequence: MVRAEIETGAPFRSVKEAVTLFGERILLGDNYISKSVERSSCKSIQDELVEAKENLKKAEEENKVLSQLIESLTQELETTKEKLNHSLRNFPEHPQVEDDLKFIEESTVNEPDNITEIKMNRFDRNEVYGDRLEKRRSVKFANPPLLTKVIVGKEEKNQVMVKKQTKKMKPLVPLAAWLFARNRSS
What are the official names of this protein?
WEB family protein At3g51220.
What is the protein family that this protein belongs to?
Belongs to the WEB family.
Protein: TILS_RICM5
Sequence: MLYEKFEYNINNLIGNFGLSKISIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIQIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHRSKPAYREEFKGDTERSTAAYTSVGEEALLRGSILSLEAKFGTMSKAAIISQQLKTNKLIENELKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRAARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQETPNCFVTHLSLEDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFAPNFVSRFTHFC
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_SYNP6
Sequence: MAAPLAQLRDRFQAALAASFGPEWAATDPLLVPATNPKFGDYQSNVAMSLAKQLGQPPRAIAETLVQNLNLADLCEPPAIAGPGFINFTLQPSYLVAQLQQLQTDERLGIQPVSPPQRVIVDFSSPNIAKEMHVGHLRSTIIGDSIARVLEFQGHEVLRLNHVGDWGTQFGMLIAFLQEQYPQALSQPDALDISDLVAFYKQAKARFDEDPSFQETARQRVVDLQSGEATARQAWQLLCDQSRREFQKIYDRLDIQLEERGESFYNPYLPAIVEDLRRLGLLVEDQGAQCVFLEGFQNKEGQPLPLIVQKSDGGYNYATTDLAALRYRLGQDQAQRIIYVTDSGQANHFAQVFQVAQRAGWLPAAAQIEHVPFGLVQGEDGKKLKTRAGDTVRLRDLLDEAVDRARTDLTTRIAAEERSETPEFIEAVAQAVGLGAVKYADLSQNRNSNYIFSFDKMLALQGNTAPYLLYAYVRIQGIARKGGIDFAQLDPVAAELTEPTERSLAKQVLQLGEVLDEVARDLLPNRLCSYLFELSQTFNQFYDRCPILNAEEPQRTSRLLLCDLTARTLKLGLSLLGISVLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKH9_CAEEL
Sequence: MCSTMTATMNQTICEKQNITMDLLRSPIQIPSASDTIKIETPSTISSQPSPIQTPLAAASSDNFERPSLSYKDLIIEAIDRSPEKRLKLNEIYQVIRLLHPYYRHRPDQWGWQNSIRHNLSLHDCFVKLPLKQTSASGVVGHFWTVVPELSDKQTLRRRNRQQPRALAKKSDAGRTLSRDDRGSSGSGETSPSPSQPSISPPNENPMPSVQALNVLELLSGMNDYKGTLFQNNYRTNLIQDNSAVNGLQNLLTTTLMQINPQLGALLSLANLNNLTTNQLQIASPSLSPIKAESQSFLLQ
What is the function of this protein?
Transcription factor (PubMed:26963674).  Binds to the regulatory elements of genes that contain the sequence motif 5'-TTGTTTCT-3' (PubMed:26963674).  Involved in regulating intestinal transcription of vitellogenin vit-2, acting in concert with transcription factors elt-2, mab-3 and daf-16, and also the TGF-beta/Sma/Mab pathway (PubMed:26963674).  Functions downstream of the insulin/IGF-1-like signaling (IIS) mediated pathway, in regeneration of axons after injury and in short-term memory, perhaps acting in neurons, and in modulation of longevity, perhaps acting non-neuronally (PubMed:26675724).  Plays a role in the modulation of endoplasmic reticulum (ER) homeostasis during chemical and pathogen stress, including exposure to the Gram-negative bacterium P. aeruginosa (PubMed:30287474).
What are the official names of this protein?
Forkhead transcription factor fkh-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPA_BURP0
Sequence: MTDLTATPAPAEPAASAYDPTAKQKAQAKTARIPIKIVPIEKLKKPEWIRVKAATGSSRFNEIKTILREHNLHTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDADEPKNLARTIAALKLKYVVITSVDRDDLRDGGAGHFVECIREVREQSPATRIEILTPDFRGRLDRALAILNAAPPDVMNHNLETVPRLYKEARPGSDYAHSLKLLKDFKALHPDVATKSGLMVGLGETTDEILQVMRDLRAHDVDMLTIGQYLQPSEHHLPVREYVHPDTFKMYEEEAYKMGFTHAAVGAMVRSSYHADLQAHGAGVV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP35_HUMAN
Sequence: MAAFAVEPQGPALGSEPMMLGSPTSPKPGVNAQFLPGFLMGDLPAPVTPQPRSISGPSVGVMEMRSPLLAGGSPPQPVVPAHKDKSGAPPVRSIYDDISSPGLGSTPLTSRRQPNISVMQSPLVGVTSTPGTGQSMFSPASIGQPRKTTLSPAQLDPFYTQGDSLTSEDHLDDSWVTVFGFPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKPCIDKSVMESSDRCALSSPSLAFTPPIKTLGTPTQPGSTPRISTMRPLATAYKASTSDYQVISDRQTPKKDESLVSKAMEYMFGW
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  May play a role in the association of MAD1 with the NPC.
What are the official names of this protein?
Nucleoporin NUP35, 35 kDa nucleoporin, Mitotic phosphoprotein 44, MP-44, Nuclear pore complex protein Nup53, Nucleoporin NUP53.
What is the protein family that this protein belongs to?
Belongs to the Nup35 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein. Note=Tightly associated with the nuclear membrane and lamina.
Protein: TECT2_RAT
Sequence: MGSLSPLSFLWGLLLLQGVLRPLRGDPVFIPPFIRMSSPEVRASLVGGSEDVTVSLTPLQIKEGVLPVPTCGGLRNETGDWNLTVSPQANMLEVTVRWKRGLDWCSPDETASFSEAPCIVQTLLVSASHNASCLAHLLIQVEIYPNTSVTHNASENMTVIPNQVYQPLGPCPCDLTAKACDIRCCCDQDCQPELRELFERFCFSGVFGGYVSPPSHHRCAARTTHQTPDWFPFLCVQSPPSTSPFLGHFYHGAISPRHSPGFETHSHLDLRDFFADASYKQGDPIMTTNGYFTIPQASLAGQCLQDAPVAFLRNFHSVCTTDLEVQERDRLIPEDMRIRTTGGLVTPTVTYEEATDLDKLITSPDTILSAGSAPRNVTVEEHYVFRWQNNSISSLDITIIRAEINAHQRGTMTQRFTVKFLSPNSGGEKEFSGNPGYQLGKPVRALHTDGMNVTTLHLWQPAGRGLCTSAALRPVLFGEDASSGCLLEVGIKENCTQLRENVLQRLDLLIQATHVARRGNSDYGDLSDGWLEVIRVDAPDAGADLPLSSANGMCPEVPTHVTIRILTAEAGAVEGEAQREILAVETRFSTVTWQYQCGLTCEEDKADLLPLSASVKFINIPAQMPRPTRFQINFTEYDCTRNELCWPQLLYPLTQYYQGEPRPQCVAKGLMLLSLLMLAILLRHPWVGMCKAWSSASIQH
What is the function of this protein?
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Required for hedgehog signaling transduction (By similarity).
What are the official names of this protein?
Tectonic-2.
What is the protein family that this protein belongs to?
Belongs to the tectonic family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.