PharMolix/UniProtQA huggingface dataset:
Protein: MPH1_MAGO7
Sequence: MGSDYDSFDDDVADEVLMALDKPATSGLHSREQEQQRDISNATPHTSTDLELEDFGSDAFDYSPERERAKPIQTARNQARTFQQTTLLGRIASQAPEPLGTQPRNSRVFRADLPPEVPTHHALDPEALKTWVYPTNLGPIRDYQFSIVKNGLFNNTLVALPTGLGKTFIAATVILNFFRWTRNAQMVFVAPTKPLASQQVEACLNIAGIPRSQSTLLTGETKPVLREAEWEGKRLFFMTPQTLMNDLSKGYADPKRIVLLVVDEAHRATGDYAYVKVIEFIRRFSKSFRVLALTATPGSTVEGVQDVIDNLGVSHVEIRTEESIDIRNYVHSREIDRVVLEPSDEMLRISELFSQALKPLHSKISQQKIYIGRDPMSITTFGLLKARQDWMKGPGRFANQGLKMMLMAIFTILQSLAHAIKLLNYHGIRPFYDNLVAFRSETEDKGQKGSKYKRQLIGEQSFQEMMDLASKWLKIDGFAGHPKLTHLCDNLLNYFMDAGEGSSTRVIVFSEYRDSAEEITRVLNVHKPMISASLFVGQADSKKSEGMKQKQQIETIAKFRDGIFNVLVATSIGEEGLDIGQVDLIICYDASSSPIRMLQRMGRTGRKRAGKITLLLMKGKEEDNYAKAQDNYEKMQKLICEGSRFNFRHDLSSRIVPRDVKPEVDKRMVEIPIENTQDTSLPEPKARSTRGKKASKKKFNMPDGVETGFNSVASMLGISASKTKAKPNKSPKKAESKETDEISPVPPLEGVLLSVKELAELNKKYRDLPFFHQDTEEICMPSLTARPDLQRVLRPTVHVKHGSYTKRCVRLFKKLSHSQGIETRHTKPHGDTDKSRYLDISVPPFAEDSGEDVVVVPSGRKRSLSPSSAASPPPPGRKRKANTTAAPRSKRQSVVDEYASESEDDTAAARQRKTNAAASPESKRQSVLDEYASESDAEAVTQASEDEESVGSLADFISDGEANGNFPKDMTGFTSDEDDDYRSGSLAKSSLSGPLSGRQVHRSSGAASKSGSTASTAAKPFFVPASLPGTQQTDDDEDMPDIGILVGKKQPETRVRKPAKKSNAVFLSSDDDDDDNDDEDDVQPGPAKRTVRRRVIEDSESG
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase MPH1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS6_PARL1
Sequence: MALYEHIFIARQDVSQQQVEALTEQFSNIIKEQGGQVGKTEYWGLRNLAFKVKKNRKGHYTLVNIDAPHAAVAEMERQMGISEDVLRFITVRVEEHETEPSAMMQSRGDRGDRGDRRGGDRFGDRDRGDRGDRGSSRFGDRERPRRDDNSDGGQE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NLPD_ECOLI
Sequence: MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAPANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENGRIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVGQTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSANKMLPNNKPTATTVTAPVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASEGGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR
What is the function of this protein?
Activator of the cell wall hydrolase AmiC.  Required for septal murein cleavage and daughter cell separation during cell division.
What are the official names of this protein?
Murein hydrolase activator NlpD.
What is the protein family that this protein belongs to?
Belongs to the E.coli NlpD/Haemophilus LppB family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor. Note=Localizes at the septal ring.
Protein: DNBI_EHV2
Sequence: MNSNRAAAGPVEENVGTQASVGPCGFVYLYPGDTFPVEEASLLGNLHAGGEVFSLPLLSGLTVEADFHVNVKAVHKKLDPATVSVKASAYHREVIVFANAACFKPIFAGPGLEGLCAASRQLFGYAEFEERAGGAARPFELADLGHLLPGAESHIAGVVVTESFKERLYRGQLVVVESQIQSVRVGECDAFKVPLYDGELFAKSPCRENLRYFYHAGVSRYLFEAHYTSLAQALRVRDVPGLIGALERQSFHDQYKLPKVYECREFPATGHRGAGDCSLTIVDSVATELAVSYGLSFLEVPQEGTALLSYDKWPIFEGCETPEQRVEALTQFNAKQAVHVHSQLFSGNSVLYLARVQKQASNRGGGGENVYNSFFMGHGLACLAEPTQKENGLPSFPGVPASALSGSNYSLHHLAYAASFSPQMLARHCYYLQFAQHQKSSNNSGYNVPTYVGTAANTPMCELCRGSCPASCVNTLFYRLRDRFPPVVASVRRDPYVVTGVAGAYNDLDIAGNFANYRDKDEESNQSEEREKFTYWQVTQTVLERLSEAGICEGGEDVGDAIHNIGSFLKVFKEIDGIVDGEVARFINSMVKNNVNYRESIKSIHHIVQYVCNVYWQPPCPVFLNLYYRCVLAVVQDICLPTCMMYEQENPAVGVSPGEWLKMHYQTLWTNFKNSCIDKGVLTGTEYKVVHKDQFCDFFDVDSAARGEFVSCKTQVRISRALMMAPRVMKIKNRIIFSNSPGTESIQNAFVRGTPKGDSCVVSGPYMRFLSTYHSQLFPGAKISPLFLWHTFSKKRQLPVFPNVPRESVTELANYVEQNSRLHGETSIIDVVPENFYTYAKVRLNNALFRACGQTQFYATTIHCLTPKIQTVPAEEYPHALGARGVADVGEYLGAARELTVPTVQCTSRDNICEVGKCRPIVTLPLVVNKYTGVTGNSQIFQCANLGYFIGRGVDKNLIPDAGSFKKQGVSTSMRKRHVFMTPLSDHLLRRSVQGAAVAFEIEGVRRRVQQILSDGDNPHVIRDVVLQLVKSLGSECRSVSEYDLEYYMGQYYIFAGDVSERLQRLSDLGGDWSEEWALSVLGEEEDPLGGELEFEKVEDAECLGHPQQDEFALAPQAAAPQYSGSSSVAGKKRKANVILGDLDL
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: C13A8_CAEEL
Sequence: MIFELILISIVTYYFWHWTFWKRRGLPGPWGVPIFGKAGAMLEDSFPPGYTLQKWTKEYGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNFYGRKHNPVQGDPDKDKDIHIVGAQGFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREESENGKAVNMHLFYQEYTFDVISRVAMGQPDSQMFKNPLLKDVKGFFEHNRWQIWMFSGGFPFAVSFLKWLFIKVGKFGAGPFIVVQKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGESNDEFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDKECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQIVEAGVDVMIDTWTLHHDKNVWGNDVEEFKPERWDSPLTPQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTFETNAKTQLPIKLVGRATARPENLFLSLKPRV
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Putative cytochrome P450 CYP13A8.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: NAGB_LACDA
Sequence: MKIIVVKNASELGKQAFDLLAKAVDEGAKTLGLATGSSPVELYQEIVASQLDFSQMTSVNLDEYVGLSPENPQSYHYFMNQHLFQYKPFKRSYLPDGQTKDIQAECGRYNQILAENPVDLQVLGIGQNGHIAFNEPGTPFDSVTHEVALTESTIKANARFFNSIDEVPKSAICMGIANIMAAKEIVLLAKGESKAKAIKDMVEGPVTTDVPASVLQKHPNVTVIADQAAASLLK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: CPC_ARATH
Sequence: MFRSDKAEKMDKRRRRQSKAKASCSEEVSSIEWEAVKMSEEEEDLISRMYKLVGDRWELIAGRIPGRTPEEIERYWLMKHGVVFANRRRDFFRK
What is the function of this protein?
Transcription factor.  Determines the fate of epidermal cell differentiation.  Represses trichome development by lateral inhibition.  Together with GL3 or BHLH2, promotes the formation of hair developing cells (H position) in root epidermis, probably by inhibiting non-hair cell formation.  Represses the expression of GL2 and WER in H cells.  Positively regulates stomatal formation in the hypocotyl (PubMed:19513241).
What are the official names of this protein?
Transcription factor CPC, Protein CAPRICE.
What are the subcellular locations of this protein?
Nucleus. Note=Moves from developing non-hair cells (atrichoblasts) to developing hair cells (trichoblasts).
Protein: MPPA_SOLTU
Sequence: MYRCASSRLSSLKARQGNRVLTRFSSSAAVATKPSGGLFSWITGDTSSSVTPLDFPLNDVKLSPPLPDYVEPAKTQITTLANGLKVASEASVNPAASIGLYVDCGSIYETPASYGATHLLERMAFKSTLNRSHLRIVREIEAIGGNVTASASREHMIYTYDALKTYVPQMVEMLADCVRNPAFLDWEVKEQLEKVKAEISEYSKNPQHLLLEAVHSAGYAGPYGNSLMATEATINRLNSTVLEEFVAENYTAPRMVLAASGVEHEEFLKVAEPLLSDLPKVATIEEPKPVYVGGDYRCQADAEMTHFALAFEVPGGWMSEKESMTLTVLQMLMGGGGSFSAGGPGKGMYSRLYLRVLNQYPQIHAFSAFSSIYNNTGLFGIQGTTSSDFGPQAVDVAVKELIAVANPSEVDQVQLNRAKQATKSAILMNLESRMVASEDIGRQLLTYGERNPVEHFLKAIDAVSAKDIASVVQKLISSPLTMASYGDVLSLPSYDAVSSRFRSK
What is the function of this protein?
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain.  Mediates formation of the complex between cytochromes c and c1.
What are the official names of this protein?
Mitochondrial-processing peptidase subunit alpha, Alpha-MPP, Inactive zinc metalloprotease alpha, Ubiquinol-cytochrome-c reductase subunit II.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: ETFB_MYCTO
Sequence: MTNIVVLIKQVPDTWSERKLTDGDFTLDREAADAVLDEINERAVEEALQIREKEAADGIEGSVTVLTAGPERATEAIRKALSMGADKAVHLKDDGMHGSDVIQTGWALARALGTIEGTELVIAGNESTDGVGGAVPAIIAEYLGLPQLTHLRKVSIEGGKITGERETDEGVFTLEATLPAVISVNEKINEPRFPSFKGIMAAKKKEVTVLTLAEIGVESDEVGLANAGSTVLASTPKPAKTAGEKVTDEGEGGNQIVQYLVAQKII
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases.  It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit beta, Beta-ETF, Electron transfer flavoprotein small subunit, ETFSS.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: DABA_STAAT
Sequence: MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNVDVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTHFSIDQEDYQAYVEGHLLALPGWAGMLYYRSQQHYFEQHLLTDYLAIRLVVEQLLVGDEFKSVAKDCESRSENWFKQTVASWCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQMGTSTKAQIAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETTVFAVAEHHTSTDTLAWVYVPDTLSSIALDAYESLNDAMPMISEHANRERLDKLPTIGRVNHPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTLLNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRTMYHSPIRLLVVIQAPDYVVARLLANNEHFARKVSNHWLRLMSVNEEGRFKSWI
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSBI_PORPU
Sequence: MFTLKIFVYTTVIFFISLFVFGFLSNDPSRNPNRKDLE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RPOC_RHIE6
Sequence: MNQEVMNLFNPQVPAQNFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTLKDVERVLYFENYIVTEPGLTALKEHQLLSEEEYMLAVDEYGEDQFTAMIGAEAIYEMLASMNLEKIAGDLRSELADTTSDLKQKKLMKRLKIVENFMESGNRPEWMIMKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSILNQNEPGEGMAFSDLGELHHALESKVVTLHTKIRGRFKSVDEDGKPYSKIYETTPGRLLIGELLPKNGKVPFDICNQEMTKKNISKMIDTVYRHCGQKDTVIFCDRIMQLGFAHACRAGISFGKDDMVIPATKAKIVADTENLVKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDENTGRQKPMNSIYMMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIVTHVDCGTETGLTMTAIVDAGQVVASLGARILGRTALDDIDHPVTGERIVDAGKMILEPDVIEIEKAGIQSIRIRSALTCEIQTGVCSVCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTATVVDQSFLEASYEGTVQIKNRNVLRNSEGSLVAMGRNMTVQILDERGVERSSQRVAYGSKLHVDEGDKVKRGQRLAEWDPYTRPMMTEVAGTVQFEDLVDGLSVLEATDESTGITKRQVIDWRSTPRGSDLKPAIVIKDASGNVAKLSRGGDARFLLSVDAILSVEPGTKVSQGDVLARSPLESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTIRLGRDYKNKRRVIIEPAEDGVEPVEYLIPKGKPFHLQDGDYIEKGDYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVEITDAGDSTYIVGDNVDRIELEDVNDHLIEQGKKPAHGDPVLLGITKASLQTPSFISAASFQETTKVLTEAAIAGKTDGLQGLKENVIVGRLIPAGTGGTMTQIRRIATSRDELILEERRKGTGAAVATPMLQDMAEKAPAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: Y1588_LISMC
Sequence: MKISFHGQSCIKIITGDTTILVDPFISGNEKCDLKAEEQMPDFIVLSHGHDDHVGDTVEIAKNSGATVICNADLASFLAVEDGLENIAPMHIGGKRQFSFGQVKLTQAFHGSQTVRDGRIVNLGFPTGIVFTIEDKNIYFAGDTGLFSDMKLIGELNPLDVAFLPIGDNFTMGPEDAAIAARFLQAKLVVPMHYNTFPLIAQDPHKFVASLDEGITGKVLEIGEGIEI
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Lm4b_01588.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: PA2AB_BUNCA
Sequence: AVCVSLLGAANIPPQPLTFLQFNEMIECTIPGSFPLLDNMDCGCYCGTGGRGTPVDMLDRCCKEHDDCYAQIKENLKCSSLLNVPYVKQYSFTCSEGDLTCSDAAGTCARIVCDCDRTAALCFAEAPYKRRNFKIDYKTRCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 Bc-PL, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SXPLT_PARLS
Sequence: LCEKFKVQRLVELNCVD
What is the function of this protein?
Shows moderate insect toxicity coupled with mild effect on mice.
What are the official names of this protein?
Toxin Plt.
What are the subcellular locations of this protein?
Secreted.
Protein: ORTT_ECOLI
Sequence: MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATWPMSFPVALLFSLF
What is the function of this protein?
Acts as an orphan toxin which is important for maintaining cell fitness during stress related to the stringent response (decreased amino acid, purine and thymidine availability).  Overexpression inhibits cell growth and increases the formation of persister cells.  Causes 99. 9% of cells to undergo bacterial lysis within 2 hours after induction; nucleoids condense, the cytoplasm seems empty and the periplasmic space enlarges.  The intracellular ATP level decreases about 27-fold suggesting the membrane potential may be disrupted.
What are the official names of this protein?
Orphan toxin OrtT.
What is the protein family that this protein belongs to?
Belongs to the GhoT/OrtT toxin family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLYA_DICNV
Sequence: MFTKAMNIADFDNELAQAIADEATRQEDHIELIASENYCSPRVMEAQGSCLTNKYAEGYPRKRYYGGCEYVDIVEELAIARVKMLFAADYANVQPHSGSQANAAVFLALLEPGDTVLGMDLDHGGHLTHGSKVSFSGKTYNSIGYGIDDKGLIDYDAVAQLAEKHRPKMIIAGFSAYSQVLDFQRFREIADSVGAYLMVDMAHVAGLVAAGLYPNPVPFADVVTSTTHKTLRGPRGGIILAKANPTIEKKLNSAIFPGSQGGPLMHVIAAKAVAFKEALEPSFQKYQEQVVENAKTMAKVFIARGYDIVSGGTQNHLMLVSLINKGLTGKAANDALSRAHITVNKNSVPNDPQSPFVTSGIRIGTPAITTRGFGVNEVKKVANWICDVLDDIDNEEVILNVRNKVAELCAEFPVYGQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIGI7_ACET2
Sequence: MYSVTINQRVEAIKNNEEEINLFVEEYKPFIAACTQKVVGRYVAYGQDDELSIALMAFVETIRSYDVSKGNFLSFSQNVIKRRIIDYYRKEKKHSVVVNINGHLEDEEEETDLGIAMSIDKYSEEEISEYRRLELEQLKKELKEWDISFFDLVNISPKHKRTKKIYSKIIKFVLSRPDIMEKIKQKKYLPVAEIEQSLKIPRKTIERARKYIITVVIIFTGDYEFIRDYVNWEVE
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
What are the official names of this protein?
RNA polymerase sigma factor SigI7.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. SigI subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_HAES1
Sequence: MRLCDTDIERYLDQGIISLTPRPSNEKINGATIDVRLGNSFRVFREHTAPFIDLSGPKEEVTAQLDAVMSDEIIIGENEAFFLHPGELALATTLEAVKLPANIIGWLDGRSSLARLGLMVHVTAHRIDPGWEGKIVLEFFNSGKLPLALRPNMVIGALSFEVLSGTAARPYTSRKDAKYKHQQSAVASRISEDK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: G6PI_MESH7
Sequence: MSLKLEVKTEIKLDYQGFQNQINEFHKRINDKNSPDINFLGWNNFPEVAINPQEIARMRKIVENLHQNSINVLVVIGIGGSYLGAKAALDFILGLGPFENKPEVIFLGNSLSSTDLYQKIEYLKTKNFAINVISKSGSTIEPAITFQILYQFLIDQIGEKLAKTRTFVTTSIKSGELLEIAKSNELEIFEVIESIGGRFSVLSSVGFFPLLFAKINVDEIIQGAIEAHKKYSTSSISQNLAYKYALFRFLMYKNFNYKTEILISYEPFLIYFNEWWKQLFGESEGKNLKGLFPASAIFTTDLHSLGQFIQDGSKNFFQTIIYIKKPKFDLGIKKLVQFNSKINKLSGKTVSEINFQAFLATTLAHSSYGNNPNLVLEIADSSPKTFGHLVMFFEKACAMSAYLLGVNPFDQPGVESYKNELAKNLGWDR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_ECOLU
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQAGLSASVN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: COG6_ASPFU
Sequence: MESYFPSGAIANHSFIRASSPASTPLSPPTQRSNALSNRLTSVLSASYADSDIRDALETLSLRGVHNTAETRRQLRLDVQKEVVECNAEIVRDFGKVAEQLQRIGTVISSLNQTCEEMRQHIVRAKQDTAPVIEEASALMNQKKESETKQQLLDAFVKHFIVSEDDLLVLTSAEEPIDDRFFNVLDRVKQVHHDCEVLLGGENQRLGLELMEKSSRNLNSAYQKLFRWIQKKFKSLNLEDPRISSSIRRALRVLAERPSLFHSCLDFFADARDYALSDAFHYALTDTVSGSGGDRNVKPIEFSAHDPLRYVGDMLAWVHSTTVSEREALEALFVADGEEIAKGIQAGLSSEPWSRIDEGEEVSFDGRKALNDLVNRDLVGVSRALRQRIELVIQGHDEPVTCYKVVHLLSFYRATFSRLLGTKSNLADMMQTLEKFTFSRFESLMLEQVNTLSNDHAALTPPDDLSAPEFFLDALEELTSLMKTHDASLEAEDAESESTAENKFTPVLRVAFDPFLQLAKSSAAELPDATARAIYTTNVLLTARSTISAFAFASATHMDPISTALSSLRMELLEIQHRYLLDASGLGVLLTALEPFAPSPTISKPESEGKDGHAPPQVDKQPTDIAEIADLPAFQPEALIAVGQQLDDFLPSALMDATDNLKHLQSASFVQSVTEEAVEAFCRDFEFVEGMIIGADEARGRVHIKRMEDGSDAGVQDDVATESGKVSDGDEQESKLRRLFPRTTGEIRVLLS
What is the function of this protein?
Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking.  COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 6, COG complex subunit 6, Component of oligomeric Golgi complex 6.
What is the protein family that this protein belongs to?
Belongs to the COG6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: AROQ_METRJ
Sequence: MNDTVLVLNGPNLNLLGKRQPEIYGRETLADVEALCRETAAGFGLAVDFRQSNAEHALIDAIHEFRVGSAGIVINAGAYTHTSVALLDALNTCEVPVIECHISNVHRREAFRHHSYISLAATSVLAGFGTHGYALAIRHLAHLRAGRPA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RL22_WOLTR
Sequence: MKSMDPIIGASSRILRSTPRKLNLVADLVRNKKVSFATVQLRFCEKKAAGLIGKVLNSAIANAQYNYGLDIDNLYIKEILIGKSFTLHRVCPKAMGRANRVSKHYSNITIKLRQIV
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.