PharMolix/UniProtQA huggingface dataset:
Protein: PNP_POLAQ
Sequence: MTMFKKAVKSFQWGNHQVTMETGEIARQSGGAVIVNVDDTVVMGTVVASKSAKPGQSFFPLTVDYLEKTYAAGKIPGGFFRREGRPSEGETLISRLIDRPLRPLFPEGFLNEVQVVIHVLSINPDVPSDIPALIAASAALAISGIPFAGPVGAARVGYANGQYLLNPTRTEQATSELDLIVAGTQAAVLMVESEANQLSEEVMLGAVVYGHDQMQTAINAINELVAEAGKPEWDWTAAPKDEPFIAKVTALAEAPLREAYQIRQKGARSDKLKEITKEVMAKLQEEGDVDAVAVNDILFEIEAKIVRSQILNGEPRIDGRDTRTVRPIEIRNGVLPRTHGSALFTRGETQALVVATLGTARDEQIIDALEGEYRDRFMFHYNMPPFATGETGRVGSPKRREIGHGRLAKRALIPVLPSAEDFAYSIRVVSEITESNGSSSMASVCGGCLAMMDAGVPVKAHVAGVAMGLILDGNRFAVLTDILGDEDHLGDMDFKVAGTANGITALQMDIKVQGITKEIMQVALAQAKEGRLHILSKMQEAMGSVRTELSAHAPRMVSFKIHPDKIREVIGKGGATIQALTKETGCSIDIKDDGTVTIASTSAEGMAEAKARIEGITAEAEVGKIYEGPVVKLLEFGALVNILPGKDGLLHISEISNERVKEVKDYLAEGQVVRVKLLAADERGRLRLSLKAAMADEGGTIAPLAGAAEVVAEEAPASGESA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_SODGM
Sequence: MLFEPALKPARLIQRYKRFLADVVTPDGEALTLHCPNTGAMTGCATPGDTVWYSASDNRKRRYPHSWELTETASGQWIGVNTLHANTLVGEALRAGTIPELAGYAHLRGEVRYGAENSRIDWLLSAEGRADCYIEVKSVTLLQHQSGYFPDAVTLRGQKHLRELQAMAEMGYRAVLFFAVLHSGIDRVSPARHIDPHYADLVLQAQQYGVEVLCYGCQLSRHGMRIHTPLPIIIS
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RLMH_BRASO
Sequence: MHMRLVVIAIGRLKQGPERQLAERYRERFDDIGRKLGFRGLDIHEIPESRARDAATRMAEEAAAIAAAIPDNSMLVCLDERGHNIDSATFAGHIGRWRDEGVAATAFVIGGADGLSPELRRKAKLGVAFGAATWPHQIVRVLLLEQIYRTATILAGHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKI31_ARATH
Sequence: MSVSDEEDECFARFLESEVSSVEDKEETKEPEAKRQRIEKGETKALEKDEDQKENGNKDKTDAKRIESGVFTNVPTELFRHILKFLSSEDLVSCSLVCKFLNFAAADESLWRRLYCIRWGLTLPSRKLRESAWKKLYIDRDEQDMIELVRTCPSDFKEYYVHMQAAKRSQAPLPSQMVDDRIILDNTVLEQVSLWKKSKGLTDKAVTGHICLGTKCSYHQIDDVFICKETGNVHVCDDNCKEVILSPEGDLMVCTISGVCSDTLLVQTEPDADGCYEEEAELEAEVFTDKSRLARAFELGYNCDDEQELERTLRFC
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
F-box protein SKIP31, SKP1-interacting partner 31.
Protein: G1PDH_THEAC
Sequence: MEFQKFRTMHFPRDVYIGHDVLEHIVDVVGENSRNKNAIIVSGDLTYELAGRKVHDLLSTYGYEVHVFLAGNANYDTLERIEYESLDIQAGIVIGVGGGAKIDLAKKLAFDRKLPFVSVPTAPSHDGIASPRASLRRNGISYSEEGAMPIGVIADTAIMIKAPYRYLAAGAADVISNLSAVKDWKLAHRLKGEEFSSSAAAMSEYSAQEVLSQINEIKKYEESSVWLVTKNILASGTAMAIAGNSRPGSGSEHLFAHALEAAGVENMLHGEMCAMGTVISMYLHDENWQQIKEAFDNLGISIRSRDYGIEDEIVINALRTAHAIRPERYTILGESDMSYDAAVKALELTGII
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIN37_HUMAN
Sequence: MFPVKVKVEKSELEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTPSDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERECSPSSPLPPLPEDEEGSEVTNSKSRDVYKLPPPTPPGPPGDACRSRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYERQ
What are the official names of this protein?
Protein lin-37 homolog, Antolefinin.
Protein: PSAD2_ARATH
Sequence: MATQAAGIFSPAITTTTSAVKKLHLFSSSHRPKSLSFTKTAIRAEKTESSSAAPAVKEAPVGFTPPQLDPNTPSPIFAGSTGGLLRKAQVEEFYVITWNSPKEQIFEMPTGGAAIMREGPNLLKLARKEQCLALGTRLRSKYKITYQFYRVFPNGEVQYLHPKDGVYPEKANPGREGVGLNMRSIGKNVSPIEVKFTGKQSYDL
What is the function of this protein?
PSAD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.  PSAD may encode the ferredoxin-docking protein (By similarity).
What are the official names of this protein?
Photosystem I reaction center subunit II-2, chloroplastic, Photosystem I 20 kDa subunit 2, PSI-D2.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: CHEB_OCEIH
Sequence: MRKVRAIVIDDSAFMRKIISDILDNDPRIEVVAVARNGEDGLNKVIQLSPDVVTLDVHMPKMDGMQALQRIMNEHPVPVVMLSSVTKAGAEKTIQAISNGAVDFIMKPSGSISLDIRNVEDEIRKKVILASTVRVKSTQEASEEDFQSTRTVPTINREKKYRRSIVSIGTSTGGPKALQKVLTELPKDIQAPIVIVQHMPPGFTKSLADRLNSICAISVKEAVHGEILQSGTAYIAPGGFHMQVENVGMSLAIALDKSPPLKGHRPSVNKLFSSLQHIKNYNKITCILTGMGNDGTDGLQQLRLNEGSTISLAESADTAIVYGMPKAAVNAGLIDYEMSLHEIPSLIVKQLT
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCDB_LACLA
Sequence: MGRKWANIVAKKTAKDGATSKVYAKFGVEIYAAAKQGEPDPESNSSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMVIAETLTSNVNRTIANVRTTFHKNGGNIGAAGAVSYMFDNTGVIVFEGTDPDHIFEILLDAEVDVRDVTEEEGNIVVYTEPTDLHKGIAALKEAGITEFSTTELEMIPQSEVELSPEDLEIFEGLIDALEDDDDVQKVYHNVANL
What are the official names of this protein?
Probable transcriptional regulatory protein YcdB.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_BIFLD
Sequence: MSNETATLVKLSAAEQAAAVKKGDVTSRELVEAHLKVIEAAEPSIKAFLKVSGDVALEQADAFDAKSAEDKAALPELAGVPIAIKDMIVTKGIETTAASKILEGWVPPYDATVIEKLKAAGMPILGKTNLDEFAQGSSTEHSAYQTTHNPWDTERVPGGSGGGSASAVAAFEAPIALGTDTGGSIRQPGALTGTVGVKPTYGGVSRFGAIAMASSLDQIGPVSRTVLDSALLQEIIGGHDKRDSTSIPEGPRPMVAAAREGAKRDLKGMKVGLIKELGGDGFQPGVEARFNEAVDKLKEMGAEVVEVSVPHIGYSLGAYYIIMPSEVSSNLARYDGMRYGLRVMPPTGVPQTAANMMAYTREAGFGDEVKRRIILGTYALSAGYYDAWYGSAQKVRTLIIEDFKKAFEQVDVLVAPTSPSTAFKFGEKMDDPLAMYMNDIATIPANLAGVPAMSIPAGLSDDGLPVGFQFIAPQQRDEVMYKPAAALEAALEDSWNGPIWNDLKTPWLDGLGK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: TRMB_ASPTN
Sequence: MGNSRNKRGKREANRQRTVEALARAQSGADTGAALQLPQKKFYRQRAHANPFSDHQLKYPLSPAHMDWASHYPAFENPDPAQTNLGGFRKLLKDVEVVDIGCGFGGLLIGLAPLLPETLIVGMEIRIQVLDYVNTRIQALRTQQRHFKLKSAGGGGSDAAPESPAAPPTPSEAASPDSTTPSEQQAPTTLVPGGFQNISAIRSNTMKFFPNFFGRGQLSKIFICFPDPHFKARKHKMRIISETLNAEYAYALRPGGLLYTITDVEEYHHWILRHFREPEVDGAVPCDDGADGIKELFERVSDEELQQDPCVEVMREATEEGKKVSRNKGNKYVAVFRRKADPEWPA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMO_BRUO2
Sequence: MSAPRVSFVSLGCPKALVDSERIITGLRSEGYEISRKHDGADLVIVNTCGFLDSARDESLEAIGLALNENGKVIVTGCLGAEPDVIRERHPNVLAITGPQAYESVMNAVHEVAPPPPHDPFVDLVPPQGVKLTPRHYAYLKISEGCSNRCSFCIIPALRGDLVSRPINEVLREAEKLVQAGVKEILVISQDTSAYGLDIKYQEAMWQDRTVRTKFLDLSRELGEMGVWVRMHYVYPYPHVDEVIPLMAEGKILPYLDIPFQHASPAVLKNMRRPAHQEKTSRRIQAWRETCPDLAVRSTFIVGYPGETEEDFQMLLDWLDEAKIERAGCFKYEAVKGAKANDLGLEQVPEEVKEARWHRFMAKQQQISTNLLKKKVGKRLPVIIDEANGTIGKGRTRYDAPEIDGSVHISSRRPLRVGDIVTVKIEASDAYDLHGTAV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TERT_TAKRU
Sequence: MSITDLSPTLGILRSLYPHVQVLVDFADDIVFREGHKATLIEESDTSHFKSFVRGIFVCFHKELQQVPSCNQICTLPELLAFVLNSVKRKRKRNVLAHGYNFQSLAQEERDADQFKLQGDVTQSAAYVHGSDLWRKVSMRLGTDITRYLFESCSVFVAVPPSCLFQVCGIPIYDCFSLATASLGFSLQSRGCRERCLGVNSMKRRAFNVKRYLRKRKTETDQKDEARVCSGKRRRVMEEDKVSCETMQDGESGKTTLVQKQPGSKKRSEMEATLLPLEGGPSWRSGTFPPLPPSQSFMRTLGFLYGGRGMRSFLLNRKKKTAEGFRKIQGRDLIRIVFFEGVLYLNGLERKPKKLPRRFFNMVPLFSQLLRQHRRCPYSRLLQKTCPLVGIKDAGQAELSSFLPQHCGSHRVYLFVRECLLAVIPQELWGSEHNRLLYFARVRFFLRSGKFERLSVAELMWKIKVNNCDWLKISKTGRVPPSELSYRTQILGQFLAWLLDGFVVGLVRACFYATESMGQKNAIRFYRQEVWAKLQDLAFRSHISKGQMVELTPDQVAALPKSTIISRLRFIPKTDGMRPITRVIGADAKTRLYQSHVRDLLDMLRACVCSTPSLLGSTVWGMTDIHKVLSSIAPAQKEKPQPLYFVKMDVSGAYESLPHNKLIEVINQVLTPVLNEVFTIRRFAKIWADSHEGLKKAFIRQADFLEANMGSINMKQFLTSLQKKGKLHHSVLVEQIFSSDLEGKDALQFFTQILKGSVIQFGKKTYRQCQGVPQGSAVSSVLCCLCYGHMENVLFKDIINKKSCLMRLVDDFLLITPNLHDAQTFLKILLAGVPQYGLVVNPQKVVVNFEDYGSTDSCPGLRVLPLRCLFPWCGLLLDTHTLDIYKDYSSYADLSLRYSLTLGSCHSAGHQMKRKLMGILRLKCHALFLDLKTNSLEAIYKNIYKLLLLHALRFHVCAQSLPFGQSVAKNPAYFLLMIWDMVEYTNYLIRLSNNGLISGSTSQTGSVQYEAVELLFCLSFLLVLSKHRRLYKDLLLHLHKRKRRLEQCLGDLRLARVRQAANPRNPLDFLAIKT
What is the function of this protein?
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes.  It elongates telomeres.  It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
What are the official names of this protein?
Telomerase reverse transcriptase, Telomerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the reverse transcriptase family. Telomerase subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: CX07_CONZO
Sequence: GFRSPCPPFC
What is the function of this protein?
Strongly inhibits the human alpha-3-beta-4/CHRNA3-CHRNB4 (IC(50)=15. 7 uM) and alpha-7/CHRNA7 (IC(50)=77. 2 uM) nicotinic acetylcholine receptor (nAChR).  Incomplete inhibition of responses is observed for both subtypes, indicating a potential non-competitive mode of action.
What are the official names of this protein?
Conotoxin Czon1107.
What are the subcellular locations of this protein?
Secreted.
Protein: YVAF_BACSU
Sequence: MDKRILAETFRLIKQKGFSFTMNDLAAALGTSKRTLYAYYSSKDQLVEAVVEQFIAEMKQIERDIYENESLNVLEKVKQMLISLPQGMELLNMGLLNELKKYHYDAWLTLDAFIKEEWAIVLALLNECKQQKRIRNINPDLFVHMYIGSINQVYDPEYPLKHQFTTGEVLESIVDVLFNGITADEEADAT
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YvaF.
Protein: GLMU_XYLF2
Sequence: MPLSLPLHIVILAAGEGKRMKSALPKVLHPIAGKPMLAHVITTARALTPDAIHVVYGHAGNQVRAAFADQTDLHWVEQTQQLGTGHAVKQTMSAIPNAANVLVLYGDVPLIRAETLQRLPRASTPIAVLVTELANPAGYGHIVRNSEGKVAAIIEDKDADEEQRRIHTVNTGILCAESTALRRWLSKLSNTNMQGEYYLTDIFASATADLTPANMIMVTDAQEVEGVNDLWQLTQLERAWQIRAARALCLQGARVADPARLDQRGTIRIGQNVHIDIDVVLEGEIELGDNVVIGPFVRLKNVKLGPGTKVHAHCDLEGVTTTGSALIGPFARLRPETMLADGVHIGNFVETKNTSIGADSKANHLTYLGDAQIGTKVNIGAGTITCNYDGVNKSITLIGDGAFIGSHSALIAPVSVGAGATLGAGTVLTHDAPAHQLTVARARQTTLDGWQRPKKKT
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICK5_TRILK
Sequence: MKTLVLVAVLGLASLYLLSYASEVQQLSRDEEEFRALVASFGGLFDTEERGVDKEGCRKLFGGCVGDGDCCLHLGCKTRKLPPFADPYCAWDWTFGRK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U11-barytoxin-Tl1b, U11-BATX-Tl1b, Toxin ICK-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 25 (ICK4) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PCHDS_PENRW
Sequence: MADKITDEYAVGIDPEIYANNPAYSSLFNPYIHKQTIIADHVSVQCHIDLNGIDAVGSKFGNLNAHAGNFTSLCAPNCLPERFALVAYTVEYAFLHDALNQSGMTSVSTRVSDKAQRKSEVQAKIAAEYLRLDPVFGEWFLNKWQTFTACVKDVRSLEFPSLDDYLEFRIVDAAADWTLYNFRWGSGITLTPEEEKIADPMSYVAYAELCLVNDLFSWDKEYASHIKSNGDVPLVNAVHIVAVTQGLTHCAAKAVVQAEVRAHEERFCQLKEQYEATDKPSHEVLRWLRLLEHSMAGNWVWSLCVPRYCKVDRNPYKDHLEKYGSDAVRVLTPLDRLCWPKQEIKDMKQSELKDPSSSTYKSHFSPLEPNPGPEQMRLTISQTQQQRPVLNPYTYINSLPSKNVRQTLIAALNSWYKVPVKSLLIIEGAVNFLHNSSLLLDDIQDGSFLRRGRPVAHQIFGVGQTINTATYLMNEALYLIQMLSPSAVSVYTEIDEMRNLQLGQGRDLYWSYHTHVPTPAQYISMVDGKTGGLFRLISRLMRSEATKNSDLDISQFATLLGRHFQIRDDYQNLQSEDYTKNKGFCDDLDEGKLSFPIILSMQSPGFSNTALSSVFKGSQKGQTLSLEMKQYMLEEITARGAFSETKAVLRKLHTELLRLLIETEKKAGGVENWALRLLIMKLDIAEEKKVAPPKSDSHWGVNQRRAWKGCQKNGRPIDKACFLRAMEETLQK
What is the function of this protein?
Bifunctional terpene synthase; part of the gene cluster that mediates the biosynthesis of conidiogenone, a diterpene known to induce the conidiation (PubMed:30343633).  The bifunctional terpene synthase PchDS converts isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) into deoxyconidiogenol (PubMed:30343633).  The C-terminal prenyltransferase (PT) domain of PchDS catalyzes formation of GGPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GGPP into deoxyconidiogenol (PubMed:30343633).  The cytochrome P450 monooxygenase PchP450 then catalyzes two rounds of oxidation to furnish conidiogenone (PubMed:30343633).
What are the official names of this protein?
Conidiogenone synthase, Bifunctional terpene synthase PchDS, BFTS PchDS, Conidiogenone biosynthesis cluster protein PchDS, Diterpene synthase PchDS, DS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.
Protein: THRE_MYCTU
Sequence: MDQDRSDNTALRRGLRIALRGRRDPLPVAGRRSRTSGGIDDLHTRKVLDLTIRLAEVMLSSGSGTADVVATAQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSRLAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGAAGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQRVFGAGIATLVAVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTGYMLTALARLGDALFLTAGIVVGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLGAAGFGRVVATWTAAIGVGFLATLISIRRQAPALVTATAGIMPMLPGLAVFRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPTGTGGQRWRSVALEPTTADDVDAGYRGDWPATCTSATEVR
What is the function of this protein?
Catalyzes the export of L-threonine and L-serine from the cell to the extracellular environment (By similarity).  Export is dependent on the proton motive force (By similarity).  Required for in vitro growth and survival of bacteria inside macrophages (PubMed:35287590).
What are the official names of this protein?
Probable threonine/serine exporter.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YPFJ1_PLAF7
Sequence: MSNRQSIDDMNLSVKNKKSKSIFSCRPVKYVCLSVAVAAVGYANYMNNGDRNSLSCVDLNNVYSRNLSESQENHNSSFTRTNLVENENEEDDIFGVHRDESFAETVLNGQDIISYLEHQNTKIHEDNIHDDISHTLLNEGDVQNYYDVLNVNEHSDLNELKRNFHNLSLQHYPKITSDNSFELNDEFNQLSEAYQVLSYQIRKNIYDNEGVYGTKKMAIVNPLIYFNGIFTTQLMHEYIGTTEVAQFVQLFLERNIAPENIVSFLEESVSDMMKGQDYRELQLTELLKQKLDLYINDDEKWQNIIKSEINVLTKSPFSKFILEAVGWTYENVGNIYMEQTDNFDNVYHGIYVNLADERINRNYAILDENVNDFVSLLKKFYPFTETVNPYLRRAKHNLNNLQGGINNLYSSVNVVYDNLFNENINISSNEHYHLLQELLKIILNINLCDIEETIRECAYNVLKDKTVDASVHSKRAHRMNILGSLMLESSNE
What are the official names of this protein?
Uncharacterized J domain-containing protein PF3D7_1401100.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS2_ACTSZ
Sequence: MAQVSMREMINAGVHFGHQTRYWNPKMKPFIFGARNGVHIVNLEKTLPLFNEALAELTRIANNNGKILFVGTKRAASEAVKAAAVDCQQFYVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALDRSREMAKLELSLGGIKDMAGLPDAIFVIGADYEHIAIKEANNLGIPVFAIVDTNSSPDNVDFVIPGNDDATRAIQLYLTAAAAAVKEGRKAEQAVEEKFSEEAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: HFLD_ESCF3
Sequence: MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSIIDMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL
What is the function of this protein?
Negative regulator of phage lambda lysogenization.  Contributes to the degradation of the phage regulatory protein CII.  Acts probably by holding CII on the membrane surface, away from the target promoters, but close to the FtsH protease.
What are the official names of this protein?
High frequency lysogenization protein HflD.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EF1B_YEAST
Sequence: MASTDFSKIETLKQLNASLADKSYIEGTAVSQADVTVFKAFQSAYPEFSRWFNHIASKADEFDSFPAASAAAAEEEEDDDVDLFGSDDEEADAEAEKLKAERIAAYNAKKAAKPAKPAAKSIVTLDVKPWDDETNLEEMVANVKAIEMEGLTWGAHQFIPIGFGIKKLQINCVVEDDKVSLDDLQQSIEEDEDHVQSTDIAAMQKL
What is the function of this protein?
Catalytic subunit of the guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) of the eukaryotic elongation factor 1 complex (eEF1).  Stimulates the exchange of GDP for GTP on elongation factor 1A (eEF1A), probably by displacing GDP from the nucleotide binding pocket in eEF1A.  The 30-fold higher concentration of GTP compared to GDP in cells favors the formation of eEF1A-GTP, which rapidly forms a ternary complex with aminoacyl-tRNA that in turn displaces eEF1B from the complex.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, Eukaryotic elongation factor 1Balpha, eEF1Balpha, Translation elongation factor 1B alpha.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: UVRB_COXB1
Sequence: MSKAFKLTSKFKPSGDQPQAIEKLVAGLEDGLAYQTLLGVTGSGKTFTIANAIEKVQRPTLILEPNKTLAAQFYAEMREFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDASINDHIEQMRLSATKAITERHDTIIIATVSAIYGLGDPDSYLKMLLHLTRGDQIDQRKILQRLAELQYTRNDLELRRATYRVNGDIIDIYPADSEREAVRVELFDDEVENLSYFDPLTGEMLRRVPRITVYPKTHYVTPREKLLSTLDQIKIELKERLSQLEKANKLVERQRLEQRTKFDMEMILELGYCSGIENYSRYLSGRNEGEPPPTLIDYLPKDALLIIDESHVTIPQLGGMYRGDRARKETLVEYGFRLPSALDNRPLRFDEFEKLAPQTIFISATPGPYEEKQSDQVVELLVRPTGLIDPEIEVRPVATQVDDLLSEIKKRAAQNERVLVTTLTKRMAEDLTEYFTEHNVRVRYLHSDIDTVERVEIIRDLRLGVFDMLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTMGRAARNVHGKAILYADRITDSMKRAMEEAERRRIAQSAYNEKHHITPKSIQKAVTEIIEGARTYTERGRFVNQAQLIAEEEAKYIAMTPKQLAKELRKLEEQMYHHARNLEFEEAAAVRDKIQHIRKGLLEVKE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPRA_STRR6
Sequence: MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGKTIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF
What is the function of this protein?
Protein that helps load RecA onto ssDNA during transformation (PubMed:17803906, PubMed:22904190).  Required for DNA transformation (PubMed:9535083, PubMed:10223974, PubMed:12123453).  Not required for DNA uptake but for a later stage of transformation (PubMed:12123453).  Thought to interact at the cell pole with newly imported transforming ssDNA which it binds cooperatively, protecting linear and circular ssDNA from nuclease action (PubMed:14617176, PubMed:17803906).  Forms bridges between DNA segments (PubMed:17803906).  Favors the loading of RecA onto ssDNA and formation of RecA-DNA filaments, triggering RecA-catalysis of ATP-driven homologous DNA pairing (PubMed:17803906).
What are the official names of this protein?
DNA processing protein DprA.
What is the protein family that this protein belongs to?
Belongs to the DprA/Smf family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the cell poles during competence (By similarity).
Protein: OBG_BORT9
Sequence: MHTFKDSLNITVSSGSGGAGCVSFLRERFKAKGGPDGGDGGRGGNVVFKVKPDLKTLSFYKNGQKLAANNGKPGMGSRKSGASGEDLVIFVPPNTRVYDVFTDSMLFELQNFDDEVIALKGGRGGLGNVNFKSSTKRTPRFAQPGESGTTLDLRLELVLIADIGLVGLPNAGKSSLISTITASRSKVGNYPFTTKVPHLGVLKSSYEDLVIADVPGIIEGASRGMGLGFEFLRHISKTKILVFLIDVASNDFMSTYSILVNELSVYDVGLSSKKRIIVANKLDLEGAIENFNQLKRALDGEKVLGISIYDNRGIDELVNELFALSRI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.