PharMolix/UniProtQA huggingface dataset:
Protein: PSTB_RHOPA
Sequence: MTEISIATSVPSAMPPIGAQPDGPAKVTVRDLNFYYGQNHALKHINLALATNRVTAFIGPSGCGKSTLLRIFNRMYDLYPGQRAEGQVLLDNANILDPKLDLNLLRARVGMVFQKPTPFPMTIYENIAFGVRLYEKISKSEMDGRVEKALRGAALWNEVKDKLNASGLSLSGGQQQRLCIARTIAVRPEVILFDEPCSALDPISTAKIEELIDELKEQYTIAIVTHNMQQAARVSESTAFMYLGELIEFGPTNKIFTSPSDRRTQDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PATS_METJA
Sequence: MKVAIVFDSAGTLVKIMRVIKDLKKNKFICNSQTVDIVDKKKGRALVIIKEDPLKVVDKENPEKLISDLLKEVEIGISYCNPPINREGIFKDRKTKVKELQEPLNILKRYEVETGYGSALIIDTYAGEVEYTIATAGCLFKEVKETIKQLKDLGVKVFIASGDRKGFIKRLAEITGVDERYIMAEAHQELKRDLIRNLKKEGYFTIMVGDGANDVPAMIESDLAVVTLQNGNVSRRALETADIKIYNIKEIVDICKKVINGEIKGRMQIKECS
What is the function of this protein?
Most probably acts as a phosphatase in the cytosol.
What are the official names of this protein?
Soluble P-type ATPase-like phosphatase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
Protein: SYL_BURM7
Sequence: MHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTYENIAYMKKQMQAMGLAIDWSREVTTCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGAFVEKREIPMYYMRITQYADELLNDLDGLGWPERVKVMQHNWIGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLARDKPALQAFIDECKRGGVAEADIATMEKKGVATGFSVSHPLTGEPVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTRAVCVNSGKYDGLAYDAAVDAIAAELKAGGLGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDLVPDGTGNPLAKSDAFLNCTCPKCGAVAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYREDAAGKKTWYNPADVTVSFDDKGRPVGAVLKSDGQPVELGGIEKMSKSKNNGVDPQMLIDHYGADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDAAQLAEAGKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRVLYPVVPHVTFELWKVLGYADEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKDASREAIEAAAVADGMFAKFAEGRPAKKIIVVPGRLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_STRMU
Sequence: MTNRKDDHIKYALDYRSPYNSFDDIELIHHSLPDYDLAEIDLSTHFAGQDFDFPFYINAMTGGSQKGKEVNEKLAQVADTCGLLFVTGSYSTALKNPDDTSYQVKKSRPHLLLATNIGLDKPYQAGLQAVRDLQPLFLQVHINLMQELLMPEGEREFRSWKKHLSDYAKKLQLPFILKEVGFGMDVKTIQTAIDLGVKTVDISGRGGTSFAYIENRRGGNRSYLNQWGQTTAQVLLNAQPLMDKVEILASGGIRHPLDIIKALVLGAKAVGLSRTMLELVEQHSVHEVIAIVNGWKEDLRLIMCALNCQTIAELRNVDYLLYGRLREGQRQ
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGR11_CYCAE
Sequence: MQIILPDILQTWAYARLLNPHYDGAKLESSLWIHPLVAKLFDQKGQKAFQNDYTSLLASLMYSHQGKVPSRRCDMMNLFFVYDEYTDVVSPEIAHRLSKIVVDAMKNSDEMSPCGEHPIGDKAKEFWRLATTLLPATGSNSDVCKSRFINLTEEYLNAVTVEARDRNEGTIHSVKEYLTMRRATSGAGLMLALIEFELDLPKAVLEHKFVQALEEIYTRTRVSSGQANHNLITVVMHENPGLSLQGAFDWLGSYAAGVVECFQTNVRNLPSFCDVEGPACESVDGTLQERVDKYISGLGQAVRAEDDWAFETTRYYGEDGPKVRETRVLVIRPVKRITRRHLLQSLEIKYSMVRG
What are the official names of this protein?
Sesquiterpene synthase-like protein Agr11.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: MNMA_SHEB9
Sequence: MTSIEPTHTGKKVIVGMSGGVDSSVSAYLLMQQGYQVEGLFMKNWEEDDNNEYCAAAEDLKDAQAVCDKLGIKLHTVNFAAEYWDNVFEYFLAEYKAGRTPNPDIMCNKEIKFKAFLEFADEILDADYIAMGHYVRRRDNTDGSTQMLRGVDGNKDQSYFLYTLSHEQVARSLFPVGELEKHEVREIAKEMGLITHDKKDSTGICFIGERKFTEFLGTYLPAQPGNIETPEGEVIGTHQGLMYHTLGQRKGLGIGGMKNSNDDPWYVVDKDLERNVLIVGQGGHHPRLMSTGMTVNQLHWVDRTGPIDGCHIAVKTRYRQQDVPCTLTYTDEHTLRVVFDEPVAAVTPGQSAVFYDGEVCLGGGIIDQLIRG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H25_ARATH
Sequence: MAHRILRDHEADGWERSDFPIICESCLGDNPYVRMTKANYDKECKICTRPFTVFRWRPGRDARYKKTEVCQTCCKLKNVCQVCLLDLEYGLPVQVRDTALNISTHDSIPKSDVNREFFAEEHDRKTRAGLDYESSFGKIRPNDTIRMLQRTTPYYKRNRAHICSFFIRGECTRGDECPYRHEMPETGELSQQNIKDRYYGVNDPVALKLLGKAGEMGTLESPEDQSIRTLYVGGLNSRVLEQDIRDQFYAHGEIESIRILAEKACAFVTYTTREGAEKAAEELSNRLVVNGQRLKLTWGRPQVPKPDQDGSNQQGSVAHSGLLPRAVISQQQNQPPPMLQYYMHPPPPQPPHQDRPFYPSMDPQRMGAVSSSKESGSSTSDNRGASSSSYTMPPHGHYPQHQPYPPPSYGGYMQPPYQQYPPYHHGHSQQADHDYPQQPGPGSRPNPPHPSSVSAPPPDSVSAAPSGSSQQSADAAVTTGSSQ
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 25, AtC3H25.
Protein: RL14_BEII9
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRKYAGVGDIIVVSVKEAIPRGRVKKGDVMKAVVVRTAKDIKRADGSVIRFDTNAAVLINNQSEPVGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PP2C5_PARTE
Sequence: MGPYLSQPKTEKSTVTGQNQVFQYAATHMQGWRNTMEDAHISDMNIEPDVHLFAVFDGHGGSEVAIFAERHFREELMKNKNYQQKNYEKALTETFFKIDKMLQEPSGQDELNKIRGVNDETSLAGCTANVALIVGKTLYVANAGDSRSFLNRDGKPFDMSKDHKPDDDQEKKRIERAGGFVSDGRANGNLSLSRALGDLEYKKDSRFKPEEQIISALPDVKVTQLTASDKFLLMGCDGVFETWDHQQILNFVNQELKSSQNLQKATEKLLDQLLAKDTSLGTGCDNMTCILVLFK
What is the function of this protein?
Enzyme with a broad specificity.
What are the official names of this protein?
Probable protein phosphatase 2C 5, PP2C 5.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: BR1B_LITBE
Sequence: FLPAIAGMAAKFLPKIFCAISKKC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli.  Has activity against C. albicans.
What are the official names of this protein?
Brevinin-1Bb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: LGB1_PEA
Sequence: MGFTDKQEALVNSSSEFKQNLPGYSILFYTIVLEKAPAAKGLFSFLKDTAGVEDSPKLQAHAEQVFGLVRDSAAQLRTKGEVVLGNATLGAIHVQKGVTNPHFVVVKEALLQTIKKASGNNWSEELNTAWEVAYDGLATAIKKAMKTA
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin-1, Leghemoglobin I.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: YA042_YEAST
Sequence: MSSCISPESSIISRFTRSHGIDGNVTSILSSSFACRSRSTTNCGLVTTELNCPHSFTSRNNVVKMHDKVISPPALVRTRTSSSVLANASSDSNVDLFMMSIVSSYVCYITVLLRMYTRHKTSFPL
What are the official names of this protein?
Putative uncharacterized protein YAL042C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PURA_THEYD
Sequence: MSTVVIIGAQWGDEGKGKIVDFLTEKCDYVVRFQGGCNAGHTVVVGEEKYILHLIPSGILHKNKKCIIGNGVVLDPSGLLKEIETLTQKGVEIDNNLYIAKHCHLIMPYHVAIEEQSEKKKKIGTTKKGIGPCYTDKIARNGVRMIDLLYPDVLKNKIRANLEIINFLLKNLYNAETLDETEILTQYLNYAEKLKKYIADADILINKAIDSGKKVLFEGAQGTLLDIDHGTYPYVTSSNTIAGGACTGAGVSPRKIDNIIGIVKAYTTRVGEGPFPTEIKDSLGEEIRKRGGEYGATTGRPRRCGWLDLVGLRHAVRVNGFTGLAITKLDILDGIEKLKVCVGYKYGNSILEDFPKEIQILEDCMPVYEEFQGWKESTAGIKNYEKLPDNAKKYLKFIEDSLKVKIQIISTGQKRDEIIIKESPL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_STAA3
Sequence: MSKVHVFDHPLIQHKLSYIRDVNTGTKEFRELVDEVGMLMAYEVTRDLELQDVDIETPVTKMTAKRLAGKKLAIVPILRAGLGMTDGILSLVPAARVGHIGLYRDPETLKAVEYFAKLPQDITERQIIVVDPMLATGASAIEAITSLKKRGAKNIRFMCLIAAPEGVEKMHEAHPDVDIYIAALDEKLNDKAYITPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NDK_CAMHC
Sequence: MQQTLSIIKPDAVEKGVIGKIIDRFESAGLRIAAAKKIKLSKCDASQFYAIHKERSFFNDLVDYMTSGPVVVMVLEGENAVAKNRELMGATDPKKAAPGTIRADFAESIDANAVHGSDSEENAKNEIAFFFAGREIC
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_RHOPB
Sequence: MTTPSRIVTPERRVDDVGDTALRPQLLSEFVGQQQARANLQIFIDAARKRGEALDHVLFVGPPGLGKTTLAQIVARELGVGFRATSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEVLYPAMEDFQLDLIIGEGPAARSVKIELSKFTLVGATTRAGLLTNPLRDRFGIPVRLNFYTIAELESIVTRGARVLSIGITPDGANEIARRARGTPRIAGRLLRRVRDFASAADKSAIDRGIADHALSALEVDAAGLDAMDRRYLSTIAMNYGGGPVGVETMAAALSEPRDAIEDIIEPFLIQCGYLQRTPRGRLLTSHAFKHLGLAEPARDAAQFGLFGQGGEEG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: XOL1_CAEBR
Sequence: MDKTNFPPPINHDFHVHKSSSLPIEEDVGDNAPGPKIVGIAPHVVDKMGSLIMAVNKYCKATTRVESPSKPRSAEEHIIEMADSFHGDIRRGLIRNLLRDLELTRVYRIQITGEHDYNGRISQTAVLVAIWRSLKSFEHPYDRTFGEDCIWSNAETFYAMVKDYNFESAAKLSVLGATIFDNELKYFYDEKMDEDIQNPKGFRTLSSVGMLAEYDFVFVSTNLHTPKYTPELFWDKENPKARFERVKENVHYPDDNFAHQMVYFSDRRVASTSIPPSPIVKLTHQGLHAVNRNESDLIGFEIQQGGFLVVLKKGVFLADHTWMIQIASKLVENDESNSLEEIYFHLLEPGKRSEEWKPNLLKYMDENHHATVSLKKKTVQFAEPIFFGLTSEEEPKNKPPSHNPKPRDPADRSLSNDDTFDTASTS
What are the official names of this protein?
XO lethal protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Xol-1 subfamily.
Protein: TNFA_HORSE
Sequence: MSTESMIRDVELAEEELAKKAGGPQGSRRCLCLSLFSFLLVAGATTLFCLLHFGVIGPQREEQLPNAFQSINPLAQTLRSSSRTPSDKPVAHVVANPQAEGQLQWLSGRANALLANGVKLTDNQLVVPLDGLYLIYSQVLFKGQGCPSTHVLLTHTISRLAVSYPSKVNLLSAIKSPCHTESPEQAEAKPWYEPIYLGGVFQLEKGDQLSAEINQPNYLDFAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: ZFAN6_MOUSE
Sequence: MAQETNHSQAPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPAASVSSLSESLPVQCADGSVPDAQSALDSTSSSMQPGPVSNQSLLSESVAPSQVDSTSVDKAVSETEDLQGPRAEGLVPLECDPPSSVSDTTQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI
What is the function of this protein?
Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis.  Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1 (By similarity).  Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6.  In vitro involved in PEX5 export from the cytosol to peroxisomes.
What are the official names of this protein?
AN1-type zinc finger protein 6, Associated with PRK1 protein, Zinc finger A20 domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_SODGM
Sequence: MIPLSHGLILAAILFVLGLTGMIIRRNLLFMLLGLEIMINASALAFVVAGSYWGHADGQVMYILAVTLAAAEASIGLALLLQLHRRRRTLDIDSVSEMHG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IFI6_BOVIN
Sequence: MRQKAVSLFLCYLLLYTCGCCEEEDEKRYSEENSDSSFWGMVTYMAVGGGLMAAALPMLGFASTGIAANSLASSLMSWSAVANGGGVPAGGLVATLQSLGASGGSALMAKIGAFLGYTVHKQVESRQKESKEKK
What is the function of this protein?
Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (By similarity).  However, it has also been shown to have a pro-apoptotic activity (By similarity).  May have an antiviral activity (By similarity).
What are the official names of this protein?
Interferon alpha-inducible protein 6, Interferon-induced protein 6-16, Ifi-6-16.
What is the protein family that this protein belongs to?
Belongs to the IFI6/IFI27 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SPEB_NEIMB
Sequence: MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPYDMAVSGRSGARFGPEAIRRASVNLAWEHRRFPWTFDVRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNGSEYDHGTMFYTAPKEGLIDPSRSVQIGIRTEHSKKLPFTVLSAPKVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSFAPGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLYLQGAKKD
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: REBL1_HUMAN
Sequence: MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRCHLM
What is the function of this protein?
Binds GTP and exhibits intrinsic GTPase activity.  May activate NF-kappa-B-mediated gene transcription.  Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
What are the official names of this protein?
GTPase RhebL1, Ras homolog enriched in brain like-1 c, RhebL1c, Ras homolog enriched in brain-like protein 1, Rheb-like protein 1, Rheb2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rheb family.
What are the subcellular locations of this protein?
Endomembrane system; Lipid-anchor; Cytoplasmic side. Cytoplasm.
Protein: AZF3_ARATH
Sequence: MALEALNSPRLVEDPLRFNGVEQWTKCKKRSKRSRSDLHHNHRLTEEEYLAFCLMLLARDGGDLDSVTVAEKPSYKCGVCYKTFSSYQALGGHKASHRSLYGGGENDKSTPSTAVKSHVCSVCGKSFATGQALGGHKRCHYDGGVSNSEGVGSTSHVSSSSHRGFDLNIIPVQGFSPDDEVMSPMATKKPRLK
What is the function of this protein?
Transcriptional repressor probably involved in abiotic stress responses.  Binds DNA in a sequence-specific manner and can repress the transactivation activity of other transcription factors.
What are the official names of this protein?
Zinc finger protein AZF3, Zinc-finger protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPD_BACHK
Sequence: MYTLIIPAAGQGKRMGAGKNKLFLLINEVPIIVHTLRAFEKDKACKNIIMAINEEERPYFEELMQKYPVEKPVQFIQGGAERQDSVYNAIQHTTDVEYVLVHDGARPFVTNKVIQDVLTAAEKYGASICAVPVKDTVKKVEQGVVVETVERSQLKAVQTPQGFSVSLLLEAHRSAKQSCFLGTDDASLVERIGKQVGVVEGSYYNIKVTTPEDLLIAESFLHVQKK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: MTMRC_MOUSE
Sequence: MLGKGGVGGGGGTKAPKPSFVSYVRPEEIHTDEKEVTEKEVTLHLLPGEQLLCEASTVLKYVQEDSCQRGVYGRLVCTDFKISFLGDEDSALDNGGEAQFKNKIIGVNDVPLHCVDQIYGVFDEKKKPLFGQLKKYPEKLVIHCKDLRVLHFCLRYTKEEEVKRIVSGIIHHTQSPKLLKRLFLFSYAAAVHGTATDSRNCTVMFDTPKDWCWELERTKGSVKYRTVSVNEGYRVSDRLPAYFVVPTPLPEDDVRRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGALQVQKSFLDGIYKTIHRPPYEMVKTEDLSSNFLSLQEIQSAYCKFKQLFLIDNSSEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECLEAQNVNVLLLEENASDLCCLLSSLVQVMMDAHCRTRTGFQSLIQKEWVMGGHSFLDRCNHLHQSDKEEVPIFLLFLDCVWQLVHQYPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRENLDAQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEKPKLDRGQQKGSRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDDLQDSSREFYDSWHSKPTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGRVATMGKLLEMMEEVQSLQEKIEARHHRQEAVHAEAPGLLRNSVRLSSLFPFALLQRHSAKPVLPTSGWKALGGEDDLAKREDEFVDLGDV
What is the function of this protein?
Acts as an adapter for the myotubularin-related phosphatases (PubMed:23818870).  Regulates phosphatase MTM1 protein stability and possibly its intracellular location (PubMed:23818870).  By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (PubMed:23818870).
What are the official names of this protein?
Myotubularin-related protein 12, Inactive phosphatidylinositol 3-phosphatase 12.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Sarcoplasmic reticulum. Cytoplasm, myofibril, sarcomere. Note=Localizes to punctate vesicles when associated with MTM1 (By similarity). Localizes to triads, a structure formed by a T tubule and two sarcoplasmic reticulum terminal cisterna (PubMed:23818870). In skeletal muscles, co- localizes with MTM1 in the sarcomere (PubMed:23818870). Partially localizes to the sarcoplasmic reticulum in skeletal muscles (PubMed:23818870).
Protein: NUOB_DESRM
Sequence: MEIKDQDKAANPVAKDEMYEETVKRLKKLGAEPAVIGEVARTVSVGPLEKLLNLARANSLWPMGFGLACCAIEGLMAANMARFDLARFGYEVMRASPRQADVMLVCGTVTKKAAPFVVRLYEQMAEPKYVIAMGSCAISGGPFVDSYSVVPGVDKLIPVDVYIPGCAPRPDAVIHGFMKLKEKIINPEVVKRGDER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KINX_DICDI
Sequence: MGSVDTSVPSFDRAWSIKYEDLDFISEIGSGGFGKVFKGEYLGAPVAIKKIHILPDDPNRVDLEKFLNREIETIKLFTHPNVIQFVGISENNGILFIVTELIEGGDLQYYLKNQSIDLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIVEEDNNKSMTICGTDNWMSPEMITGLDYDERSDIFSFGIVLLEIISRVKPAPYMRDASFGLAEDIVRNQLIPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQIKTTLDSNIVYPEIRDFEQQQKISTTNGNNKQNGGAPKINNLPLQYSNNNNNIYDDDDDDDDDDDDNDSFPRPYSDNSNSNVTLESNSNYNSSTINGQEQQEQQEQQQQQQVKEERDEGEIEQDDDNIEVYDSDYQKKLEEHQKELLERQNQNQEGSTDENEVYEQEEEEEEEDEEEQVISTPAKKRISFGQDTFHTYEAYRTDDEDDDDDEEDEEEGDEYDHGYDDFDEDDEDDEEYDEDEDDEDERQIQYYQQQLQYQQQLQKQQEQEYQRQQQLQLQREEEEYQRQLQQQQQQQQQQQQQQQQHQQQYDDDDDDDDEEEEEYDDVIRHDTDSEEESKDKTPLPWDQHFEKQKESENKVEQEETNVVVANSQETEQQQQQQQQPKEEEEEEPTKVEDVKVETEEQTKEEHDVKVDEESTKVDEPVDEPTKVEESVEQVKAEEPNKVEELVEEVKVEEEPTNVEEVKAEEPVEEVKVEEPVEEVKAEEPVEEVKAEEPVEEVKTEEPVEEVKVEEPVEEVKVEEPVEEVEAEESVQEPVEEVKVDEPTKVEEPTKVEEPIEEVKVEEPTKVEESIEEVKVEEPTKVEEPVEEIKPEEPTKVEESVEDVKVEDVKVEEVKAEEPTKAEESVEDVKVEEPIKVEEPVKVEEPVKVEEPVKVEEPIKVEEPIKVEEPIKVEEPIKVEEPIKVEEPVKVEVASPVVQEQPPQQEEKPEVVSTSTITIASSPQQSSNSPPSTPVKQPQQQEIEVNSTPIKQQQQQQQTPTQQTQTPTKQHTEINVQPTPTKTPPLPPQTNEKIPLISPNNKSNRGCCSCFIQ
What are the official names of this protein?
Probable serine/threonine-protein kinase kinX.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Protein: H32_TETPA
Sequence: MARTKQTARKSTGAKAPRKQLASKAARKSAPATGGIKKPHR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.