PharMolix/UniProtQA huggingface dataset:
Protein: UVRC_VIBPA
Sequence: MNPPFDSASFLKTVTHQPGVYRMYNADAVVIYVGKAKDLQKRLSSYFRKKVDSEKTRALVSNIAKIDVTVTHTETEALILEHNYIKQYLPKYNVLLRDDKSYPYILISGHKHPRLSMHRGAKKRKGEYFGPYPDSGAVRETLHLLQKIFPVRQCEDTVYSNRTRPCLMYQIGRCAGPCVSSIISDEEYAELVGFVRLFLQGKDQQVLKQLIEKMEVASQQLRFEDAAKFRDQIQAIRRVQEQQYVSEDSMDDMDVLGFAQENGIACIHILMIRQGKVLGSRSHFPKIPQNTSQQEVFDSFLTQYYLSHNEARTIPSRIILNQELADDLEPIQKALSEVAGRKVHFHTSPTGARGRYLKLSNTNALTAITTKINHKMTINQRFKALRETLGMESIMRMECFDISHTMGESTIASCVVFNNEGPVKQEYRRYNITGITGGDDYAAMGQALERRYSKQLDVEKIPDIIFIDGGKGQLNRAHEIIAQYWGDWPKRPIMIGIAKGVTRKPGLETLITVDGEEFNLPSDAPALHLIQHIRDESHNHAIAGHRAKRGKTRRTSALEGIEGVGPKRRQALLKYMGGLQELKRASVEEIAKVPGISHSLAEIIFQALKQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_STRA3
Sequence: MGKEKLILAYSGGLDTSVAIAWLKKDYDVIAVCMDVGEGKDLDFIHDKALTIGAIESYILDVKDEFAEHFVLPALQAHAMYEQKYPLVSALSRPIIAQKLVEMAHQTGATTIAHGCTGKGNDQVRFEVAIAALDPELKVIAPVREWKWHREEEITFAKANGVPIPADLDNPYSIDQNLWGRANECGVLENPWNQAPEEAFGITKSPEEAPDCAEYIDITFQNGKPIAINNQEMTLADLILSLNEIAGKHGIGRIDHVENRLVGIKSREIYECPAAMVLLAAHKEIEDLTLVREVSHFKPILENELSNLIYNALWFSPATKAIIAYVKETQKVVNGTTKVKLYKGSAKVVARHSSNSLYDENLATYTAADNFDQDAAVGFIKLWGLPTQVNAQVNKG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHZ7_SCHPO
Sequence: MGIPDSTTDSRHSLSSAALSSASFENIYDPARKNESTNDVIDNHTDTEIDDHDNDHENLDSNNNNENNEAFNEKAAEKKLLPWYRRYFIWILIFIVALICSVLIGVLGGVLGHRTAVRDRHPSYKAKTYSLVKEYKGTTFFDGFDFMNITDPTHGFVQYLDRNSSAKLGLISANSSNVIMAADSKHNYSSGRPSIRLQSTQYFEHGLFILDLIHLPYGCGTWPAFWTLGDDWPNGGEIDIVEGVNVGTSNQVTLHTGDGCEMEDIKRVMTGTALQTNCWVDAPNSYNAGCGVENPSGPSYGEAFNKNGGGVFVLDWRSEGIRSWFFNRSEIPSDITSGSPQPAKWSEPVADFPDTKCDIDKMFSKQKILFDLTFCGDWAGSSVYSSAGCPGSCNDFVGNNPHNFTEAYWNIKSLAVYQY
What are the official names of this protein?
Probable glycosidase C21B10.07.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YI11_STRCL
Sequence: MSTRHDRIWVGIDAGKGHHWAVAVDADGETLFSTKVINDEAQVLTLIETAREREEVRWAVDISGRASTLLLALLVAHGQNVVYVPGRTVNRMSGAYKGEGKTDAKDARVIADQARMRRDFAPLDRPPELVTTLRLLTNHRADLIADRVRLINRLRDLLTGICPALERAFDYSAAKGPVVMLTEYQTPAALRRTGVKRLTTWLGRRKVRDADTVAAKAIEAARTQQVVLPGEKRATKLVCDLAHQLLALDERIKDNDREIRETFRTDDRAEIIESMPGMGPVLGAEFVAIVGDLSGYKDAGRLASHAGLAPVPRDSGRRTGNYHRPQRYNRRLRWLFYMSAQTAMMRPGPSRDYYLKKRGEGLLHTQALLSLARRRVDVLWAMLRDKRLFTPAPPVTQTA
What are the official names of this protein?
Insertion element IS116 uncharacterized 44.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the transposase IS1111A/IS1328/IS1533 family.
Protein: SELO_PSEFS
Sequence: MKALDELTFDNRFARLGDAFSTHVLPEPLDAPRLVVASPAAMALLDLDPSVAETPVFAELFGGHKLWAEAEPRAMVYSGHQFGGYTPQLGDGRGLLLGEVYNEAGEHWDLHLKGAGMTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRALCVIGSDTPVWREKQERGAMVLRMAHSHIRFGHFEYFYYTKKPEQQAELAEHVLNLHYPECREQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDAHFICNHSDHEGRYSFSNQVPIGQWNLSALAQALTPFIGVDALKEALGLYLPLYQANYLDLMRRRLGLTTAEDDDQKLVERLLKLMQSSGVDYTLFFRRLGDEPAALAVTRLRDDFVDLAGFDAWAEQYKARVERDGDNSEEQRRARMHAVNPLYILRNYLAQNAIAAAESGDYSEVRRLHEVLSKPFEEQAGMEQYAQRPPDWGKHLEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RLMN_SYNPW
Sequence: MISTAQSKTLLGLGASELERWAVSQGQSAFRGRQLHDWLYAKGACDLQDITVLPKAWRASLQDKGVIIGRLKEQDRKVAGDATTKLLLGTDDGETLETVGIPTDQRLTVCVSSQVGCPMACRFCATGKGGLQRSLYTHEIVAQVLSVREVMERRPSHVVFMGMGEPLLNIEAVLDAIRCLNDDLGIGQRRITVSTVGVPRTLPRLAELAMERLGRAQFTLAVSLHAPNQSLREELIPTAHAYPYDALLDDCRHYLAITGRRVSFEYILLGGLNDHPAHAEELADRVGGFQSHVNLIAYNPIEEEEFQRPTRDRIEGFRRVLESRGVAVSLRASRGLDQDAACGQLRRSRQK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGI_BRUAB
Sequence: MHCKILGLPVQEGTGRKGCNMGPDSYRAAGIADAIRELGHECTDLGNLAPAAQRPLQHPNHAIKALPYAVAWIEAISEAAYRESAEGFPIFLGGDHLLAAGTVPGIARRAAEKGRKQFVLWLDAHTDFHTLETTTSGNLHGTPVAYYTGQKGFEGYFPKLAAPIDPHNVCMLGIRSVDPAEREAVKKTEVIVYDMRLIDEHGVAALLRRFLERVKAEDGLLHVSLDVDFLDPSIAPAVGTTVPGGATFREAHLIMEMLHDSGLVTSLDLVELNPFLDERGRTAAVMVDLMASLLGRSVMDRPTISY
What are the official names of this protein?
Arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: TSN12_PONAB
Sequence: MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITLLWALYYDRREPGTDQMMSLKNDNSQHLSCPSVELLKPSLSRIFEHTSMANSFNTHFEMEEL
What is the function of this protein?
Regulator of cell surface receptor signal transduction.  Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction.  Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs.  Suprisingly, it only activates the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1).  Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP.  Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP).  Activates MMP14/MT1-MMP-dependent cleavage activity (By similarity).
What are the official names of this protein?
Tetraspanin-12, Tspan-12.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUSB_AERHH
Sequence: MKPSERRKARHCATQAIYQWQMTKANVGDIEEQFKIDQDTKGVDLNYFRDLLFGVALHCNELDKVFAPFLSRPLEEVDMVDKAILRLATYELTRRDDVPPRVAINEAIELAKSFAADDSHKFVNGVLDKVIKSLNKR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CSN7A_HUMAN
Sequence: MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDFASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQPSKKASKGKGLRGSAKIWSKSN
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.  The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases.  CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
What are the official names of this protein?
COP9 signalosome complex subunit 7a, SGN7a, Signalosome subunit 7a, Dermal papilla-derived protein 10, JAB1-containing signalosome subunit 7a.
What is the protein family that this protein belongs to?
Belongs to the CSN7/EIF3M family. CSN7 subfamily.
Protein: MRAY_STAAS
Sequence: MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVVIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFATISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGVH
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSB1_BOVIN
Sequence: MLSSVAAYSGAGRDLAMEPHSSVGPLQLRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALKVCIVTKEGIRGETVPLRKD
What is the function of this protein?
Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit beta type-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9.
Protein: MOAA_RHILW
Sequence: MNTRVGTIGNASLLTADAHPMIDPFGRAVTYLRVSVTDRCDFRCTYCMAENMTFLPKKDLLTLEELDRLCSAFVAKGVKKIRLTGGEPLVRKNIMYLVRRLGEKIGAGLDEVTLTTNGSQLSRHAEELYDCGVRRINVSLDTLDPDKFRKITRWGDFAKVMEGIDAAQKAGIKIKLNAVALKDFNDAEMPEIMRFAHGRGMDLTVIETMPMGEIDEDRTDQYLPLSKLRADLEKQFTLTDIDYQTGGPARYVRVAETGGRLGFITPMTHNFCESCNRVRLTCTGTLYMCLGQNDAADLRAALRATEDDALLHAAIDEAITRKPKGHDFIIDRTHNRPAVARHMSVTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: MURA1_CLOAB
Sequence: MNKFIIKGGETLNGEVDISCAKNSVLPIIAATILCGEKCTIKNCPMLLDVFVISDLLKSIGAQVDIDLNSGDMKIDTSNVKSIEPDAELVRKMRGSFLIMGPMISRYGRFKISLPGGCNIGTRPIDLHLKGLKALGVNIEIGHGYVEANAAKLLGDRIYLDFPSVGATENIIMASVFAEGETIIENAAQEPEIDDLINFLNKMGSDIKKIETGAIIIRGVKELKGIKYTPIYDRIEAGTFIIAAAITKSKIKINGVEEKSIKPMIAKFCEMGINMEIDGKSLIIDGRNELKPVDIKTMPYPGFPTDMQAQIMSLLCCTEGTSVITETIFENRFMHVPELKRFGANIKIDGRSAVIVGVKELTGCSARATDLRAGAALILAGLVAEGETQISDIYHVDRGYVSIEKKLTKLGAKIERVE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_DICT6
Sequence: MKIALDAMGGDYAPLETTKGALEAIKESNITVVLVGKEEELQKILKDYEYDKSRIEIVNAEEVIEMHEHPAFAVKEKENSSIVKAIKLLKERKVDGAVSAGNTGAVMSSALLYLGRIKGIKRPAISTLIPTLTEVPSIILDIGANVDCKKEYLEQFALMGKIYMEEVFNIKDPKIALLNIGEEEGKGNQLAQETYNLLKNNPIFNFIGNVEGKDLFKGIANVIVCDGFVGNIAIKTAEGVAETLFELLSSEIKSSLWSTILGMLLKPKFKNVKKKLDYSEFGGAPLLGVDGTVIISHGRSKAKAIKNALKLAEKVVKLEINRKILEGLSKITDRGD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ECFA_AYWBP
Sequence: MISIQNLTFYYGCNPILKDINLTIQNNSWVSIVGHNGSGKSTLAKILLGLLAFNKGQIVIDNIVLNEKNLPILRPKIGIVFQNPDYQFTGLTVREDIAFGLENYNVCREEIIAKVLKYAKMVKIDDLLDKNVNQLSGGQKQRVTIASILAMEPEIIIFDEATSFLDPQGALEVQKIIQTIKNKILITITHDLDFASKSDEIIVLYQGKLITQRPPKNLLQDPLFLQQYKLTPPLSLQLYYEILKDSTTKKIKNNQMLENLKDILWQYNLKK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA, ECF transporter A component EcfA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EFTS_WOLPM
Sequence: MKMNPDDIRELRDRTGLGLSDCKKALEECDGDIKKAVDKLRTIGLAKADKKSDRVASDGLVAMCLTENCGVLIELNCETDFVARNEKFIELVLNLASIAHQERCTSVDELKNAKYESIGTVQEAIMNGTSVLGEKLELSKLCYLEAKDGVIAGYVHGDVCGLGKIGALIALQSSGDKAKLQEIGKQIAMHVVAMKPEALSIDDLDQMKLNNERSIIEEQVRSLNKPEEVAKKIVDGRMAKYYEEVVLLEQKFIKDDKMKISDFIKSSELSAVKLSNYELLVLGDAD
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1433Z_MOUSE
Sequence: MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB.  Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (By similarity).  In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity).
What are the official names of this protein?
14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, SEZ-2.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes.
Protein: PDE8B_HUMAN
Sequence: MGCAPSIHVSQSGVIYCRDSDESSSPRQTTSVSQGPAAPLPGLFVQTDAADAIPPSRASGPPSVARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTCYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIVIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSDDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITINDVPPCISQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
What is the function of this protein?
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.  May be involved in specific signaling in the thyroid gland.
What are the official names of this protein?
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, HsPDE8B, Cell proliferation-inducing gene 22 protein.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
Protein: SUFS_YERPS
Sequence: MNFPIERVRADFPLLSRQVNGQPLVYLDSAASAQKPQAVIDKELHFYRDGYAAVHRGIHSLSAEATQQMEAVRTQVADFIHAASAEEIIFVRGTTEAINLVANSYGRHFLAAGDSIIITEMEHHANIVPWQMLAQDLGVEIRVWPLTATGELKITALAALIDDTTRLLAVTQVSNVLGTVNPIKDIVAQAKAAGLVVLVDGAQAVMHQPVDVQALGCDFYVFSGHKLYGPSGIGILYGKSALLQQMPPWEGGGAMIKTVSLTQGTTFADAPWRFEAGSPNTAGIMGLGAAIDYVTELGLLPIQQYEQSLMHYALAQLSQIKSLTLYGPTERAGVIAFNLGQHHAYDVGSFLDQYGIAIRTGHHCAMPLMAFYQVPSMCRASLALYNTREDVDRLVAGLQRIEKLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1095_DICDI
Sequence: MVNNNKRKEIENQENDNDDDNDGLLTYKKFKDVDYDSIRSKELQTIAKSLGLPNNGKKQEVYKRIEGYFLSKKVKNDLTNSTTNQPPQLQQKQPQQKQYVLLIKDVDQLEIYFWKAFRNMIIFKNIFSNFKSKQFGYHDLIGINENFLKSYSNSLEIIKDNIKGNINHQIIRSVNDIVNIIKTLKKKDNETISFYTTLFSTFSSSSSTTTTMQSTKSLIFQFDENIDLWIQRMILNENLVALDQFIKFFKINSDVLKKSIEMHINPSFFNVFSYNNLKIYNYLKSINAIPTSHIKQRFSNIDLSESLSFDYKFKRLIKSYKLLVDPTKFKEIREIHQQQQQQQQQQQQQQQQQQQEQQKQQEQKQQQQEQEQQQQQQQQQQQQQQQQQEQQQQQEQQQQEQQQEQEQQQQQQQEEQQQEQQQQQQQQQQQQEQQEQEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQREGRQLQILDYIEKLDQLILELNEIQFSHFTDDQLNSTIKNLLNQTKTTTTTPILITNNNNCSDLKDIIKKYYKSIYLFLKIIEEGKHDRNLMRPFHYYLYFKKKMNVSQLYEIFCGFFIKKYDDCLIFFKSILIDQQLERNQRLELVSKILDIENGVSFQNIGSNFNFTSFNSFCRVVFSTNDTELIDHLIKTIKKLQLAQNSKTQFPSISYIISINFQYINKNEIVDFFFENYRNETTLFDDQNQNWNNNHVNIIDHIEKIMESIGKKLQLYFVKYSNWFTNGNKNNEKKYNVNILLDQLKRAISKPLLYSFFFDSGYYCNTTLLNIFGWSLENGNEVVINFFLPNEIFKQPFRFSDIIYGAPSPNKIPNLIKLIFNNISKESIEPKLYQVKGNFNIPHLYYGRDDFIPLTSTISTTNSEEVGQFIIGETKSFDFIISPRMLFICLYYLDRFEDIFYLFDKIPEIFSSTYFPNFTKESYLYNICSSYYLELLINYFIENLNDNTINHLYNCLCVASGKGFTQIFKNILSSNKNSQSLLKVRTKTNQSSLFQLNFLCGMVLKSIDSSNFQLSNLLIDSIDFPPKNKRVLNQKYLVHLIINK
What are the official names of this protein?
UPF0746 protein DDB_G0281095.
What is the protein family that this protein belongs to?
Belongs to the UPF0746 family.
Protein: IHFB_MARMM
Sequence: MIKSELIDQLAEANPHLYHRDVERVVNTILDGITDALARGERVELRGFGAFSVRHRPARVGRNPRTGESVAVKEKHVPFFKTGKELRERVDASRESNPEIA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: TRPA_SALTI
Sequence: MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAELRSFVSAMKAASRA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: HSP70_PLEWA
Sequence: MSAPKGVAFGIDLGTTYSCVGVFQHGKVEIIANNQGNRTTPSYVAFTDTERLIGAPAKNQVSLNPQNTVFDAKRLIGRKFNDTVVQADMKHWPFKVVSDEWKPKVQVEYKGDNKTFFPDEVSSMVLIKMKEIAEAYLGHLVSNAVITVPSYLTASQRQATKDAGVLAGLNVLSIVNEPTAAAIAYDLDKAGRGELNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRMVNHFHEPFKRKHKKDITKNKRAVRRLRTACERAKRTLSSSTQASIEIDSLFEGIDFYTSITRARFEELCADLFRGPLEPVEKALRDAKLDKAQIHEIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDKSENLQDLLLLDVAPLSLGLETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNSLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSSGKQNKITITNDKGRLSKEEIERMVQEAERYKADDEAQREKVSAKNTLESIAFNMKSTVEGDNLKDKISEDDRKKIVDKCNQTISWMENNQMAEKEEYEHQQKELEKVCNSIITKLYQGGMPGGMPSGSSGAQARQGSSSTGPTIEEVD
What are the official names of this protein?
Heat shock 70 kDa protein, HSP70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CDPAS_ARCFU
Sequence: MLDLILKTIWLLLPCYTPNNFAVLVGGGTPIDFGKTFVDGKRILGDGKTWRGFVGGVAGGVLTANLQYAIEKLSGLAIYSSLPFNEFFTLTFLLAFGAMFGDLCGSFIKRRFGYERGSRFLIVDQLMFLLVALLIASLYPPFWKLFTAEIIALAVIITPALHMGINYIAYRLNLKEVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.  Can use CTP or dCTP, but not ATP, GTP or TTP.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.