PharMolix/UniProtQA huggingface dataset:
Protein: Y1367_MYCTO
Sequence: MNLDGNQASIREVCDAGLLSGAVTMVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEGKLALRDPITRWAPELCKVAVLDDAAGPLDRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLPFGQGPDVWLAALATLPLVHQPGDRVTYSHAIDVLGVIVSRIEDAPLYQIIDERVLGPAGMTDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWSTADDYLRFVRMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWVGRGFGLNLSVVTDPAKSRPLFGPGGLGTFSWPGAYGTWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKLRTAQPKFVRRTYRALGL
What are the official names of this protein?
Uncharacterized protein MT1414.
Protein: RIR2_ECO57
Sequence: MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.  R2 contains the tyrosyl radical required for catalysis.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase 1 subunit beta, Protein B2, Protein R2, Ribonucleotide reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: DAPEL_LACCB
Sequence: MKEADLITLRRQLHQIPELALQEKETHALLLKTIQGLPQTYLTIRTLPDLPTALLVKVQGRDPQRTIGYRTDIDALPVTEKTGLPFASKHSGIAHACGHDIHMTVALGILSYFAEHQPKDNLIFFFQPAEESKNGGKLAYDMGAFTGDWHIDEFYGLHDRPDLPAGTISTRLGTLFAGTTEINVDLIGKSGHAALPQNANDMIVAAASFISQIQTVVARNVGPTDSAVITFGLMRAGTIRNVIAGRAHLEGTLRGFTQQQIDFLQQRIRDIGQGIAASFNCQVKVALNQGGYYPVENNDKLTKDFIQVMKDDPDVTFVDTKPVMTGEDFGYLLNKIPGTMFWLGVNDPDSQLHAADFSPDEAALVPGVTAVVHFLEHRMLEKV
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: RNAS2_NOMLE
Sequence: MVPKLFTSQICLLLLLGLMGVEGSLHAKPQQFTWAQWFEIQHINMTSQQCTNAMRVINNYQRRCKNQNTFLRTTFANVVNVCGNPNMTCPSNKTRKNCHQSGSQVPLIHCNLTTPSPQNISNCGYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
What is the function of this protein?
This is a non-secretory ribonuclease.  It is a pyrimidine specific nuclease with a slight preference for U.  Cytotoxin and helminthotoxin.  Possesses a wide variety of biological activities (By similarity).
What are the official names of this protein?
Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: PP1B_DROME
Sequence: MGDFDLNVDSLIQRLLEMRSCRTGKQVQMTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPSEKKAKYLYSGMNSSRPTTPQRSAPMLATNKKK
What is the function of this protein?
Required for cell adhesion in non-muscle tissues and in maintenance of muscle attachment.  Vital for larval development.
What are the official names of this protein?
Serine/threonine-protein phosphatase beta isoform, Protein flap wing.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
Protein: RL3_MYCSJ
Sequence: MARKGILGTKLGMTQVFDENNKVVPVTVVKAGPNVVTRIRTPERDGYSAVQIAYGEISPRKVNKPVTGQFAAAGVNPRRHLAELRLDDESAAADYEVGQELTAEVFSDGAYVDVTGTSKGKGFAGTMKRHGFKGQGAAHGAQAVHRRPGSIGGCATPGRVFKGTRMSGRMGSDRVTTQNLVVHKVDAANGVLLIKGAIPGRNGGLVMVRSAIKRGEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CYF_THAPS
Sequence: MATNKFFKSLLFTLTIAISSFGFCVENSSAYPVFAQQGYSNPRAANGKLACANCHLNQKAIEIEAPQGVLPNSVFEIEIKVPYDVNRQQISADGKPADLNVGGILILPKGFKLASKTQISPEVKAKNKGVFISPYSTEFDNILVVGPIAGKTHQELIFPVVAPDPENNPDVKYLTYPFYAGGNRGRGQVYPTGERSNINSFGATQGGQITEITTTEKGESKITIVNSDGATTSQTLSAGLKLLVKQGDIVKQDQPLNIDPNVGGFGQEESEIVLQSSSRILGYLAFCFCLLLTQVLLVLKKKQYEKVQAAELNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PANC_CHLL3
Sequence: MQIVTDPAEMQATADKLRAGRQLIGVVMTMGALHEGHLSLVNLAREHAGTIIMTLFVNPSQFGPGEDFQRYPRPFEKDAAMARSAGVDYLFAPTPEAMYPEGFQTTVSCSGITRRFEGERRPGHFDGVATIVSKLLNITRPHVAVFGEKDAQQLALIRRINRDLDMGVQIVAAPTVRENDGLAVSSRNIYLTGDERQKAPAIHRAIQHAGEMLAAGENDLKAVAAEVAGMITENTQFKLEYAAFVDEESFEPAETVVKEHEYRLLIAAAAERVRLIDNQKFRV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR5A1_HUMAN
Sequence: MSITKAWNSSSVTMFILLGFTDHPELQALLFVTFLGIYLTTLAWNLALIFLIRGDTHLHTPMYFFLSNLSFIDICYSSAVAPNMLTDFFWEQKTISFVGCAAQFFFFVGMGLSECLLLTAMAYDRYAAISSPLLYPTIMTQGLCTRMVVGAYVGGFLSSLIQASSIFRLHFCGPNIINHFFCDLPPVLALSCSDTFLSQVVNFLVVVTVGGTSFLQLLISYGYIVSAVLKIPSAEGRWKACNTCASHLMVVTLLFGTALFVYLRPSSSYLLGRDKVVSVFYSLVIPMLNPLIYSLRNKEIKDALWKVLERKKVFS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5A1, OST181, Olfactory receptor OR11-249.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR3_CHLSC
Sequence: MGQKINPLGFRLGATQGHHSLWFAQPKSYSRGLQEDEKIKDCIKNYVQKNMRISSDYEGIAHIEIKKRIDLIQVIIYMGSKNSLMLIEGPTRGIEELQINVQKEFHSANQRLNIDITEVANPYGQPNLLAEYIARQLKKRVSFRKAMKKTIEFAEQADTKGIQVQISGRIDGKEIARVEWVREGRVPLQTIRAKIDYCSYTVRTIHGVLGIKIWVFVDDK
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ALR_SHEB8
Sequence: MNPFPRAEISSSALQTNLAALRQQAPASRVMAVVKANGYGHGLLNVANCLVSADGFGLARLDEALELRAGGVTARLLLLEGFFRATDLPLLVGHDIDTVVHHSSQLEMLEQTVLSKPVTVWLKVDSGMHRLGFTPEQFSTVYARLMACPNVAKPIHLMTHFACADEPDNSYTSVQMAAFNSLTAGLPGFRTLANSAGALYWPQSQGDWIRPGIALYGVSPVTGDCGANHGLVPAMELVSQLIAVRDHKANQPVGYGCFWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGQDAQDKVGDSALLWGKALPVEEVAEHIGTIAYELVTKLTPRVAVCLA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: GATA_WOLPP
Sequence: MNELRRLTITEMHDGLRRRNFSAVELVETHINAVENEQLNAFITKTPEIAIKAAKIADEHFLKQKDDIPPLMGIPVGVKDLFCTKGIKTTACSKMLENFIPTYESTVSNLLLKSGAAVLGKLNMDEFAMGSANTNSYFGPVENVWIRKSDGAKVVPGGSSGGSAASVAGFLCAGALGSDTGGSVRQPAAYCGVVGIKPTYGRCSRFGMIAFASSLDQAGVITRSVSDSALMLEIICGYDEKDSTSSKRTVPKFSSFINGDIKGKRIGIPKEYKMDGISDEIVHNWEKVSSNLKENGAEVVDITLPHTKYAIPVYYLICSAETSSNLARYDGVRYGFRVDADTLEEMYSLTRAEGFGKEVKRRILIGSYALSSGHYNEYYEKAQCIRALIRNDFIKAFEKIDYILVPSAPTEAFGLNEKPDPLIMCINDVFTVPASLAGLPAISVPVGLSNAGLPLALQVIGNYYDEAGILNMASVIEQNCGRIVNSLT
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: UIF_MOUSE
Sequence: MNRFGTRLVGATATPPPPPKARSNENLDKIDMSLDDIIKLNRKEGKKQNFPRLNRRLQQSGTRQFRMRVRWGIQQNSGFGKTSLSRRGRVLPGKRRPYGVITGLAARKATGIRKGISPMNRPPLSDKNIERYFPALKRKTSLLRQNEVQRKQVAVLKRPNQLNRKNNIPANFTRNGNKLSHQKDTRQATFLFRRGLKVQTQLNTEQLIDDVVAKRTRQWRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFLTKREQSDVKKVPKGVPLQFDINSVGKQTGMTLNERFGILKEQRANLTFSKGGSRFVTVG
What is the function of this protein?
Required for mRNA export from the nucleus to the cytoplasm.  Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore.  Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4 (By similarity).
What are the official names of this protein?
UAP56-interacting factor, Forty-two-three domain-containing protein 1, Protein 40-2-3.
What is the protein family that this protein belongs to?
Belongs to the UIF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle.
Protein: EFTU_SYNY3
Sequence: MARAKFERTKDHVNIGTIGHVDHGKTTLTAAITMTLAELGGAKARKYEDIDAAPEEKARGITINTAHVEYETDSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPKLVVFLNKKDMVDDEELLELVELEVRELLSDYDFPGDDIPIVAGSALKAIEGEKEYKDAILELMKAVDDYIDTPEREVDKPFLMAVEDVFSITGRGTVATGRIERGKVKVGEEISIVGIKDTRKATVTGVEMFQKTLEEGMAGDNVGLLLRGIQKEDIERGMVLAKPGSITPHTEFEGEVYVLKKEEGGRHTPFFANYRPQFYVRTTDVTGTIKSYTADDGSAVEMVMPGDRIKMTVELINPIAIEQGMRFAIREGGRTIGAGVVSKILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTMP_HUMAN
Sequence: MTSPCSPPLKPPISPPKTPVPQASSIPSPPLPPSPLDFSALPSPPWSQQTPVPPPLPLPPPPAATGPAPRHVFGLEKSQLLKEAFDKAGPVPKGREDVKRLLKLHKDRFRGDLRWILFCADLPSLIQEGPQCGLVALWMAGTLLSPPSGVPLERLIRVATERGYTAQGEMFSVADMGRLAQEVLGCQAKLLSGGLGGPNRDLVLQHLVTGHPLLIPYDEDFNHEPCQRKGHKAHWAVSAGVLLGVRAVPSLGYTEDPELPGLFHPVLGTPCQPPSLPEEGSPGAVYLLSKQGKSWHYQLWDYDQVRESNLQLTDFSPSRATDGRVYVVPVGGVRAGLCGQALLLTPQDCSH
What is the function of this protein?
Actin maturation protease that specifically mediates the cleavage of immature acetylated N-terminal actin, thereby contributing to actin maturation (PubMed:36173861).  Cleaves N-terminal acetylated methionine of immature cytoplasmic beta- and gamma-actins ACTB and ACTG1 after translation (PubMed:36173861).  Cleaves N-terminal acetylated cysteine of muscle alpha-actins ACTA1, ACTC1 and ACTA2 after canonical removal of N-terminal methionine (By similarity).
What are the official names of this protein?
Actin maturation protease, Actin aminopeptidase ACTMAP.
What is the protein family that this protein belongs to?
Belongs to the ACTMAP family.
Protein: QUEA_THEYD
Sequence: MKITELNYTLPTDLIAQKPLSERDKSRLLVLHKNTGEIEHRIFYEIVEYLNEGDILIINNTKVIPARLIAEKPSGGKIEILLIKEKKCSSQNVVWEVMTKGSYEGEVFIDEFIAELRNNCDGRYIVFKNMTSPKVRNLINEKGFMPLPPYIKRKPIQSDRQDYQTVYAKMNGSIAAPTAGLHFTKELLETIISKGVKLREITLHVGVGTFKPIKVDKLQEHKMDPEYFEIDKTLIEEIYAIKKAGKRIFSVGTTTTRALEGYASGKYEDRGSDNYKIKGSTDIFIYPEFSFKIVDALITNFHLPKSTPLAMVYAFCEMQKVKKAYREAIEKGYRFFSYGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC24_CANGA
Sequence: MFKKRSAASKTRKRVKVETPVQKPAVQKPAVAVKPVLDKSHVAKLEEEIASRPELDQKAVGEADATAVRLKRLKEQATKHDRLNSEPVASSKKIQQAANLRNTILTDFQPDVCKDFKQTGYCGYGDSCKFLHSRDDFKAGWTLATDWKIDEQKEETRKEAVPFKCVLCKESYERPVKTNCGHYFCQKCFVNRIKIDKSCFICGENTEGIAKMATDLVPMDNANKDK
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC24.
What is the protein family that this protein belongs to?
Belongs to the CWC24 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL33_NOSS1
Sequence: MAKSKGARIIVTLECTECRTNPDKRSPGVSRYTSTKNRRNTTNRLELKKFCTHCNKHTVHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: COXM1_YEAS7
Sequence: MEQNKDPQMISKHSSRLPIWVLSPREEQQARKNLKTETYKKCANFVQAMADCAKANGMKVFPTCDKQRDEMKSCLLFYQTDEKYLDGERDKIVLEKINKLEKLCQKQSSTK
What is the function of this protein?
Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.  Binds copper.  May be involved in copper trafficking and distribution to mitochondrial COX and SOD1 (By similarity).
What are the official names of this protein?
COX assembly mitochondrial protein, COX biogenesis factor CMC1, Mitochondrial metallochaperone-like protein CMC1.
What is the protein family that this protein belongs to?
Belongs to the CMC family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: TRUA_STRPM
Sequence: MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKIIIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHCRYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAAGTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQVKVILSSKNRQLAGPTISGNGLYLKEICYEN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PURA_ECO24
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN19A_HUMAN
Sequence: MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVVTQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR.  Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF19A, Double ring-finger protein, Dorfin, RING finger protein 19A, p38.
What is the protein family that this protein belongs to?
Belongs to the RBR family. RNF19 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Present in the hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specifically found in neurons from Parkinson disease patients.
Protein: SYL_ACIET
Sequence: MQDKYNHTEVERAAHAHWNANDAYRVTEDQAKPKFYACSMLPYPSGKLHMGHVRNYTINDMLTRSLRMKGHNVLMPMGWDAFGLPAENAALKNGVPPAQWTYDNIAYMKKQMQAMGLAIDWSREVATCDPDYYKWNQWLFLKMLDKGIAYRKTQVVNWDPVDQTVLANEQVIDGRGWRTGALVEKREIPGYYLKITDYAQELLDHVQIGNEKATLTGWPDKVRLMQENWIGKSAGVRFAFPHDIRNAAGERIQDGKLYVFTTRADTIMGVTFCAVAPEHPLAQHAAASNAPLAAFIEECKKGGTTEAELALKEKEGMPTGLFVTHPLTGEQVEVWVGNYVLMSYGDGAVMGVPAHDERDFAFALKYQLPIKQVVLVDGETFDFHQWQDWYGDKERGVTINSDNFSGLSYQDAVAAVAHALAEKGLGELKTTWRLRDWGISRQRYWGTPIPIIHCESCGAVPVPEKDLPVVLPQDLVPDGSGNPLAKCEAFLKVDCPCCGKPARRETDTMDTFVDSSWYFMRYCDPKNRDAMVAGGTDYWMRDQKAATGGSGMDQYIGGIEHAILHLLYARFWTKVMRDLGLVKVDEPFTKLLTQGMVLNHIYSRRTAKGAKDYFWPHDVEHVYDEAGKIVGAKLKNPAESGDGLLPVGTPIDYEGVGTMSKSKNNGVDPQQLIEKYGADTARLYTMFTAPPELTLEWNDAAVEGSYRFLRRVWNFGVKLSAIDKDAALASVAGAASLKDVQFGKEAKALRLEIHTVLKQVDYDYQRMQYNTVVSGAMKMINALEDFKATDSAGAQVALIEGFGILLRVLYPATPHIAHVLWDELGYAGTLGDLLDAAWPQVAPDALVQDELELMLQVNGKLRGAIRVAASADKAAIEQAALASEDFQKFAEGKAPKKVIIVPGRLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRDP1_ARATH
Sequence: MDKEKDHEVEWLEAQKIEISVDLLAAAKQHLLFLETVDRNRWLYDGPALEKAIYRYNACWLPLLVKYSESSSVSEGSLVPPLDCEWIWHCHRLNPVRYNSDCEQFYGRVLDNSGVLSSVDGNCKLKTEDLWKRLYPDEPYELDLDNIDLEDISEKSSALEKCTKYDLVSAVKRQSPFYYQVSRSHVNSDIFLQEAVARYKGFLYLIKMNRERSLKRFCVPTYDVDLIWHTHQLHPVSYCDDMVKLIGKVLEHDDTDSDRGKGKKLDTGFSKTTAQWEETFGTRYWKAGAMHRGKTPVPVTNSPYASDVLVKDPTAKDDFQNLIQFPEVEVVEVLLEIIGVRNLPDGHKGKVSVMFSKTQPDSLFNAERRLTILSEVGEKQVATFQCEPTGELVFKLISCSPSKIPVSREPKNLGFASLSLKEFLFPVITQLSVEKWLELTPSKGSQTDTKPISLRVAVSFTPPVRSPSVLHMVQSRPSCKGSCFFPIIGKSRLAKSSTHIVDETQTEVITLQIRNSADGGILKDDQRQVMGVTDSGETRVLAVYTGSFWSLLDSKWSLKQINASTADNPLFEILGPRVVKIFSGRKLDYEPKHCANLRSDLDFMTLVEFSKQHPYGKTVGLVDMRFGSIEAKENWLLLPGIVSAFILHTVLKKGGSEGFNVTTKDIKEESKQTKLVAATENNVNANSTNVETQTAITAPKKGSGCGGGCSGECGNMVKAANASGCGSSCSGECGDMVKSAANASGCGSGCSGECGNMVKAANASGGGYGARCKAAKASGCGGGCGGGCGGGCGDMVKSVNASGCGGGCNGECGNMVKAA
What is the function of this protein?
Plays a regulatory role in abscisic acid (ABA) signaling and tolerance to abiotic stress during germination.  May be involved in the regulation of the ABI transcriptional factors.
What are the official names of this protein?
Glycine-rich domain-containing protein 1, AtGRDP1.
Protein: RIMO_HELAH
Sequence: MQKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKSADVILINTCGFIESAKQESIQTILNAAKDKKEGTLLIASGCLSERYKDEIKELIPEVDIFTGVGDYDKIDILIAKKQNQFSEQVFLSEHYNARVITGSSVHAYVKISEGCNQKCSFCAIPSFKGKLHSRELDSILKEVEDLVLKGYKDMTFIAQDSSSFLYDKGQKDGLIQLISAIDKQQALRSARILYLYPSSTTLELIGAIENSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLNAMKQVQESFIRSTIIVGHPEENEGEFEELSAFLDEFQFDRLNIFAFSAEENTHAYSLEKVPKKIINARIKALNKIALKHQHNSFKALLNKPIKALVENKEGEYFYKARDLRWAPEVDGEILINDSELNTPLKPGHYTIVPSAFKDNILLAKVLSPF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISAA_STAEQ
Sequence: MKKTVIASTLAVSLGIAGYGLSGHEAHASETTNVDKAHLVDLAQHNPEELNAKPVQAGAYDIHFVDNGYQYNFTSNGSEWSWSYAVAGSDADYTESSSNQEVSANTQSSNTNVQAVSAPTSSESRSYSTSTTSYSAPSHNYSSHSSSVRLSNGNTAGSVGSYAAAQMAARTGVSASTWEHIIARESNGQLHARNASGAAGLFQTMPGWGSTGSVNDQINAAYKAYKAQGLSAWGM
What is the function of this protein?
Is able to cleave peptidoglycan.
What are the official names of this protein?
Probable transglycosylase IsaA, Immunodominant staphylococcal antigen A.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. IsaA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_MESH2
Sequence: MRFVDYVSIEVVAGKGGDGIISFRREAHVDKGGPDGGDGGWGGSIYFVGDSGMNTLLPFYQTKKIFGYNGENGRPKRQTGANGKDIFIKVPLGTQVFLKKSLICDIILEKKYLIAKGGRGGLGNFHFRNSKNKAPRISENGELGQNFYLDLQLKVMADIGLVGKPNAGKSTLLSLISNSKPKIANYEFTTLVPQLGVVKIYENSFVTADLPGLIQGASSGKGMGIIFLKHIERCRAIVHVIDFGSDNKNPIKDFIEIKSELEKFNKKLLDLNQIVIANKCDLPNFQFNLANFKRKFPKIKIIKSSLISAKQNEINIIKEKMFGLLEEKQKKLEIQEINTSKIEFNLKAPFLIKSRNNGFFEITGELIQKIIQKIPLNSQENILRFNAKVKKIGLWDELIKKGIKPGDLVRIYEFEFHWN
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.