PharMolix/UniProtQA huggingface dataset:
Protein: HKM10_ASPHA
Sequence: MSTFESLLARNEGLGQLFYQQMLEDPDAIAIVDGDYSLTYASLHAQATHLAQRLDQNDFVHEEPVGIVVQHGILDAVAQVAIIYAGGTCVTLDPALPNQQIERRLNRLRARYILVDTPNKSRGLPFSQIEVEDLPISTELIPTDSPYPVNLSLEHRSHLIHTSGTTSESKAVQIVGRSIVHVANYAPFEPVVKTDVVAHGNSTSFDVALFDIWAPLVQGASIAVLSKATLLDLSAFEAAIDRYKISVMAITAPLVNLAATTRPGMFSSMRVVLMGGEAVNIPAMRKIFEAGPPVHMVNAYGPTECCVYCLARKITLEDLDTGAVSIGKAIGNNIATVCDEMGKPVPDGEEGELLVGGPGVSPGYVNLPGKNAASFIEVPDLVDANGTPYHMYRTGDLVKRRPDGQYDFVGRFDHQVKIRGYRVELGAIETVLMDTGYFSEGVVMKVDSKAEGAGSALVAFAVLAPTAPPSAVTDATAALTAALPHYMIPNIHIVESIPLTNHAKVDRKQLADWCLQRQEKNMCAMQDKVPSEGASTRDQLGALWATILATPVREYSDNDDFFGLGGTSLQASLLISLIRRTFNTEVSLLALYDNSTLGQLAHIVDRNQGGALATVQNLREMWIADTMIGDALETPVGPVVDWRRDTEGRVFLTGATGFVGAFLLSDMLKMPGIHQVGCLVRAPDEATGVRRLRHALEKYNLWREEYLPKLLPLCGKLEDPWLGLGEQRFREIADWASVIFHLGALVNYTQPYSWHRPANIEGTVNVVRLACTGRSKALHYCSSISCFGPTGIINGTKVVHEDGALMPHLNALPYDHGYAQSQWVAEELLRRLIHRRFPIAVYRPGFITGHSETGACNPDDFFSRLIRACSSIGCYPGLPNQRKEFVPIDYVTSTMIHIASSSLSLGHAFHIVPPTREESPEMNDTMSLIGELTGTSIQPVSYREWIEQLSSTKDLSLQPLLPMLAEVVIDGMTRWEMYENMPTYENTNTLRALASCPDLPKFPMVDEALLRKYLDYLADH
What is the function of this protein?
Non-canonical nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of hancockiamides, an unusual new family of N-cinnamoylated piperazines (PubMed:33242032).  The NRPS hkm10 and the NmrA-like reductase hkm9 are proposed to convert two molecules of L-Phe to the intermediary piperazine called xenocockiamide A (Probable).  Xenocockiamide A is then converted to hancockiamide D via a series of hydroxylations and O-methylations (Probable).  The tyrosinase hkm6 may catalyze an aromatic hydroxylation, then the 2-oxoglutarate-dependent Fe(II) dioxygenase hkm4 and the FAD-dependent phenol hydroxylase hkm7 may catalyze consecutive hydroxylations to install 2 more hydroxy groups, and the methyltransferase hkm8 probably catalyzes two methylations using 2 molecules of S-adenosyl-L-methionine (SAM) (Probable).  The NRPS hkm11 activates and transfers trans-cinnamate supplied by the PAL hkm12 to hancockiamide D and produces hancockiamide A (PubMed:33242032).  NRPS Hkm11 has the flexibility to tolerate the bulky hancockiamide G as a substrate and the absence of the acetyl-transferase hkm3 opens up the opportunity for hkm11 to introduce a second N-cinnamoyl moiety (PubMed:33242032).  The cytochrome P450 monooxygenase hkm5 catalyzes the methylenedioxy bridge formation, converting hancockiamide A into hancockiamide G (PubMed:33242032).  Hkm5 can also convert hancockiamide B into hancockiamide C, and hancockiamide D into hancockiamide H (PubMed:33242032).  The N-acetyltransferase hkm3 finally transfers an acetyl group to 1-N of piperazine, converting hancockiamide A into hancockiamide B and hancockiamide G into hancockiamide C (PubMed:33242032).
What are the official names of this protein?
Non-canonical nonribosomal peptide synthetase hkm10, Hancockiamides biosynthesis cluster protein 10.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: CYAE_BORP1
Sequence: MAAVQVRRRGRALALALWAGFALSVGGGVRARDGLATPPAFEGQAAPAVSWPCPPPADRLDDLALLEAIDLALCHSPALRQGWARIKARSAEVGLARAPYYPSVALSAGRSAQRRSTGLGEDGVRNNVMAVTLAWRLFDSGARSAALRAAQAQLDEAAQAYGAVLQDKLAEVVGAYYEAATARQALHTAVEDTEIARRSASIAARRARAGLDSHGDVLHAQAALERARLAQAQAEGAQARALAGLAQVLGVDPATPIVLAPGPLAPQRIEDRELAQWLRDARQRHPAIKAAQAGLAAATAQVDVARATDMPTVDLSLGHYRNSSENVSVFAGSSRSVSASLNLRIPLFDGFARRHRIQGARAEVQRQEALLDQARLATGAAVARAYADLRAARASHEASLRWLKAARAAYESDLRRYEAGVGGVAELLRAQSDWLSARQRHVLYAAQLRTRALALLAAAGELGRSTIDGDPPKE
What is the function of this protein?
CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).
What are the official names of this protein?
Protein CyaE.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: NOP58_MACFA
Sequence: MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKKIVKEAHEPLAVADAKLGGVIKEKLNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGEDSSSAMGVENRAKLEARLRTLEDRGIRKISGTGKALAKTEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVEEEEEEEKVAEEEETSVKKKKKKGKKKHIKEEPLSEEEPCTSTAIASPEKKKKKKKKRDNED
What is the function of this protein?
Required for 60S ribosomal subunit biogenesis (By similarity).  Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles.  Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs (By similarity).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
Nucleolar protein 58, Nucleolar protein 5.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: Y2003_STAA8
Sequence: MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGVINNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLDVKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELIAKQGAYEHLYSIQNL
What is the function of this protein?
May be involved in multidrug export.  Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Putative multidrug export ATP-binding/permease protein SAOUHSC_02003.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2580_HALH5
Sequence: MQQIEVKRLLVNYKTLEEFRNFREFGAAELSMKDDLEANIIENDSESPFYGIYFGGKLVARMSLYRIDGKYDRYFEPPQDYLELWKLEVLEPYRGKGFGRALVDFAKSFNLPVKTNARQRSNEFWTKMGFEPVTYQTDRDRGESPYVWYPEGVKEQLSEDEGSVETLEN
What are the official names of this protein?
Uncharacterized N-acetyltransferase BH2580.
Protein: RS8_BACC4
Sequence: MVMTDPIADMLTRIRNANMVRHEKLEVPASKIKKEIAELLKREGFIRDVEYIEDNKQGILRIFLKYGANNERVITGLKRISKPGLRVYAKADEVPRVLNGLGIALVSTSKGVMTDKDARQLQTGGEVVAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TURM_CURLO
Sequence: LCPLDVLQLSSELLDIDGNEVEASRILSDITAFGGIRCPLTVVQSRGIGTIISSPYRFIAEGHPLSLKDMDGWFRVSDDEFNNYK
What is the function of this protein?
Inhibition of trypsin (By similarity).  Has anticarcinogenic activity, prevents transformation of DMBA-treated JB6 cells.  Has antipromoter activity, prevents promotion by tetradecanoyl phorbal acetate (TPA) in JB6 cells.  Prevents tertiary butyl hydroperoxide-induced mutagenesis.  Protects AT base pairs and shows antimutagenesis activity in TA102 and TA104 S. typhimurium mutagenesis tests.  Inhibits paw edema formation induced by phospholipase A2 in Swiss Wistar mice.  Prevents the release of arachidonate, the parent compound for the synthesis of prostaglandins and prostacyclins.  Has antimalarial activity, kills P. falciparum.  Has antivenom activity, nullifies the lethal effects of N. naja venom and inhibits phospholipase A2 present in N. naja venom.  Has antifungal activity, inhibits cilia formation by A. niger.  Is not toxic or allergenic.
What are the official names of this protein?
Turmerin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: HRPZ_PSESY
Sequence: MQSLSLNSSSLQTPAMALVLVRPEAETTGSTSSKALQEVVVKLAEELMRNGQLDDSSPLGKLLAKSMAADGKAGGGIEDVIAALDKLIHEKLGDNFGASADSASGTGQQDLMTQVLNGLAKSMLDDLLTKQDGGTSFSEDDMPMLNKIAQFMDDNPAQFPKPDSGSWVNELKEDNFLDGDETAAFRSALDIIGQQLGNQQSDAGSLAGTGGGLGTPSSFSNNSSVMGDPLIDANTGPGDSGNTRGEAGQLIGELIDRGLQSVLAGGGLGTPVNTPQTGTSANGGQSAQDLDQLLGGLLLKGLEATLKDAGQTGTDVQSSAAQIATLLVSTLLQGTRNQAAA
What is the function of this protein?
Harpins are proteins able to elicit hypersensitive response (HR) in non-host plants and are required for pathogenicity in host plants.  HrpZ forms ion-conducting pores permeable for cations.  Such pore-forming activity may allow nutrient release and/or delivery of virulence factors during bacterial colonization of host plants (By similarity).
What are the official names of this protein?
Harpin HrpZ, Harpin-Pss, HrpZ-Pss protein.
What is the protein family that this protein belongs to?
Belongs to the harpin HrpZ family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=Secreted via type III secretion system (TTSS), delivered into the host intercellular space. HrpZ travels through the hrp pilus and it is secreted only from the pilus tip (By similarity).
Protein: Y1392_DICDI
Sequence: MRVLSVLLVALTVAGSAYSQCTVNDASSAQLDSTFGPTTGGDALTFNNNLGNQIQIANNYNFVSNGVVQSNGGDNLVLTGTLTPANSSLTDKFSLRAAFVRTTTPSDVKRELQAGAYTSNGGTVDPSTWSFYQILPDNTKMVSLTNPNTVVTMSENPNTALQVGVGANGKNLQNGASGWFQFKATDGSVSIQSGNGEMEVVDININLGCSSTFDCVSNTYTISKASIDKSLTDQQNDQALYVDQVSTVFGNQQRFDTSSGTVNTISIDQTNGNLRLGAGFTSISDSSITVNCDLRFSPALPSANYQPKLELMNSAYVSGGGSIDPNTWAYYTVNVSGSSCTRNDGTVVTITGDQDNMYLQWGKGANGKNGNFGLSVWLNYVDAALTNPFFDINVDTVCETNPSTNLPETSPPTEQPTAPPATCPPGCIPAIPVVNVTETPAAGNSASSIEMSKLVVAILSLFILAFFH
What are the official names of this protein?
Uncharacterized protein DDB_G0291392.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: THIF_ECOLI
Sequence: MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTALQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMVLTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGELRLFDGKSSQWRSLALRRASGCPVCGGSNADPV
What is the function of this protein?
Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS.
What are the official names of this protein?
Sulfur carrier protein ThiS adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the HesA/MoeB/ThiF family.
Protein: DM7B_DROSI
Sequence: MSKRAKKRDKSTVEILQVYSASRDEEQMTDLKKTDYLPYLFNLVMPKQFYKSPNRIVMARLYPDVQKHDEQAAEYFEGFQTPCFDLPTKLFPEKTPIDKIVFMPKVMLPMGFEAGGVFGPGVLPRRCYPVDLISPDHKGPMPPLFVGLRGMKVSLSSMINTFLNMYDSPDGKEPHLYEMHATNHHYENDLAPEELMLRPDFTLSVAYTLPASMCLPSPYPYPSVPEQDNIYTPDLSKVLMLMPHQFNITVAILSTVNNPHDPSVAFATMGDDEECPKFELPNDVFPICEGVNRPIFLPKRFMPKGFDACCVFKPGSLSELWYIKRIGRFGTPQEQYNCSITPPLFVGKYTRNAASINMLEEISVHFDQKARECAKSLARLRLDALRLNSRNGSTKGFLVMESDKPTTPAGAYSVESYEEASEDGCVAKVTQECATESTDTRDDGINTADYQSQFPELEPDSEPEPEPEPQTEDEGEDEGDKKCLSCFKVDSDIDLISHAIAEMGVAELSMLGEVDPVPGVDTKLALDQLHEVFETRDEIRSNIDDLMRDHVCRMERDIMLALRQPIRKCSACAKHS
What are the official names of this protein?
DM7 family protein GD16138.
What is the protein family that this protein belongs to?
Belongs to the DM7 family.
Protein: POTH_ECOLI
Sequence: MSTLEPAAQSKPPGGFKLWLSQLQMKHGRKLVIALPYIWLILLFLLPFLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQSLQVAAISTFCCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAALDLGARPLKTFFTVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQEFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG
What is the function of this protein?
Part of the ABC transporter complex PotFGHI involved in putrescine uptake (PubMed:8416922, PubMed:23719730).  Responsible for the translocation of the substrate across the membrane (Probable).  Imports putrescine for maintenance of the optimal concentration of polyamines necessary for cell growth in the presence of glucose (PubMed:23719730).
What are the official names of this protein?
Putrescine transport system permease protein PotH.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARLY_STAEQ
Sequence: MSNKAWGGRFETQPEEWVDDFNASIDFDKNLIKQDVQGSIAHATMLAKQHIITDDEAQSIINELKNIQSDFEEGKLKFKASLEDIHLNIEHELIQRIGEAGGKLHTGRSRNDQVATDMHLYTKEQVQYIIELIASFQETIVQLADQHVDTIMPGYTHLQRAQPISFAHHIMTYFWMLERDKGRFMDSLKRIDISPLGAAALSGTTHPIDRHLTQELLGFANLYENSLDAVSDRDYIVETLHHISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLVTLKGLPLAYNKDMQEDKEGLFDAVHTLKGSLRIFEGMVASMKVNSNRLSQTVKNDFSNATELADYLVSKSVPFRTAHEIVGKIVLNCIHKGIYLLDVPLSEYQEHHENIEEDIYDYLTPENCLKRRQSYGSTGQESVKHQLKVAKALLKDNESK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_SORBI
Sequence: MATLRVDEINKILRERIEQYNRKVGIENIGRVVQVGDGIARIIGLGEIMSGELVEFAEGTRGIALNLESKNVGIVLMGDGLMIQEGSFVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEIVASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQDVICVYVAIGQRASSVAQVVTTFHEEGAMEYTIVVAEMADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSLLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELQAFAQFASALDKTSQNQLARGRRLRELLKQSQSNPLPVEEQVATIYTGTRGYLDSLEIEQVKKFLDELRKHLKDTKPQFQEIISSSKTFTEQAETLLKEAIQEQLERFSLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PEN3H_PENVA
Sequence: MRLVVCLVFLASFALVCQGQVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPISCRGISFSQARSYCSRLGRCCHVGKGYSG
What is the function of this protein?
Antibacterial and antifungal activity.  Presents chitin-binding activity (By similarity).
What are the official names of this protein?
Penaeidin-3h, Pen-3h.
What is the protein family that this protein belongs to?
Belongs to the penaeidin family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Protein: RL21_SULDN
Sequence: MYAIIKNGGKQYKVQEGDILLFDRMTLEPKATFEIKEVLAVNAGELKMGAPFLEGAVVTAEVINEGRDKKVITFKKRRRKDSKVKRGFRRDYTRVRITKIAA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TILS_BORPE
Sequence: MAAALRALDPAPARLAVAVSGGADSAMLAVAAAAALPPGCTLRLFHVHHGLQAAADQWAAQVRGLGALLGVPVDEARVTVPPGQGLGMEAAARLARYQALAGLARQHGVRHILLAHHRNDQAETVLLRLLRGTGLQGMAAMAPFSERDGVAYLRPWLDVDHAAILALAGAVRAQCGWQAVQDPTNTDPRYARAAVRTQLAPALDARWPGWQAIVARHARQMAEAAEIVAEVAQADFATLEPADAGRSFSLAAWRGLSAARQAQALRHWLASQDAPMPTEARLAELQRQLRQLHALGHDRHLRWQHAGRVVRCERGRVWIDD
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPYR_OCHDN
Sequence: XYAFGINGTXRI
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
Protein: KEFF_ECO45
Sequence: MILIIYAHPYPHYSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LEPA_ROSDO
Sequence: MTPLSHIRNFSIVAHIDHGKSTLADRLIQSTNTVADRDMKEQMLDSMDIERERGITIKAQTVRINYTAQNGEEYVLNLIDTPGHVDFAYEVSRSMRAVEGSLLVVDSTQGVEAQTLANVYHAIDADHEIVPVLNKIDLPASDCDRVAEQIEDVIGIDASGAIQVSAKTGQGIMETLESIVQNLPAPKGDRDAPLKAMLVDSWYDSYLGVIVLVRIMDGVLKKGDRIRMLSNNSTHNVDRIGVFRPEMTAIDELGPGEIGFLTASIKQVRDTRVGDTITHEKKGTEVALPGFKPSQPVVFCGLFPVDSSEFEELRDSIEKLALNDASFSYEMETSAALGFGFRCGFLGLLHLEVIRDRIEREYDIELITTAPSVIYHVYMKDGAMIELHNPADMPDLTLVDHLEEPRIKATILVPDDYLGDVLKLCQDRRGIQQDLTYAGSRAMVVYDLPLNEVVFDFYDRLKSVTKGYASFDYAMIGYRTDNLVKMSILVNDEPVDALSIMVHRERAEGRGRAMVEKLKDLIPRHMFKIPIQAAIGGKVIARETLSAMRKDVTAKCYGGDATRKRKLLDKQKAGKKKMRQFGKVDIPQEAFISALKMDG
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MHPB_KLEP7
Sequence: MHAYLHCLSHTPLVGFVDPEQAVLDEVNRVIADARRRIAEFDPELVVLFAPDHYNGFFYDVMPPFCLGIGATAIGDFASAAGDLPVPAELAEACAHAILNSGIDLAVSYNMQVDHGFAQPLEFLLGGLDRVPVLPVFINGVAAPLPGFQRTRLLGEAMGRFLNTLNKRVLILGSGGLSHQPPVPELAKADAHLRDRLLGGGKQLPPDERERRQQRVISAARRFTEDPHSLHPLNPVWDNRFMSLLEQGRLSELDAIGNDELSAMAGKSTHEIKTWVAAFAALSAFGRWRSEGRYYRPIPEWIAGFGSLSATTEI
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: PROS_HUMAN
Sequence: MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKNS
What is the function of this protein?
Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa.  It helps to prevent coagulation and stimulating fibrinolysis.
What are the official names of this protein?
Vitamin K-dependent protein S.
What are the subcellular locations of this protein?
Secreted.
Protein: HFQ_BACVZ
Sequence: MKPINIQDQFLNQIRKDNTFVTVFLLNGFQLRGQVKGFDNFTVLLETEGKQQLIYKHAISTFAPQKNVQLELE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: GLMM_NITEC
Sequence: MKKKYFGTDGIRGKVGEFPITPEFFLRLGYAVGKVLLASDWKLAADKRPTILIGKDTRISGYMLESALEAGFSAAGVDVLLSGPLPTPAVAYLVRALRIQAGAVISASHNPFYDNGIKFFSSEGSKLPDSMELQIEAELDFPIETAPSIKLGRVQRLKDEEGRYIEFCKSTFPNQLDLRGWKIVVDCANGADYQVAGHVMHELGADVVTIHANPDGFNINHECGATHIMTLQGAVLQHGADFGIAVDGDGDRVLMVSGEGVVYDGDSLAYIIAKHRQQRGVLQGGVVGTLMTNLAVEQAFERIGIPFARANVGDRYVSELLQQNDWYLGAENSGHIICRDKHTTGDGIISALQVLYALRDTGLMFADLMHDVTFFPQRLINVKISRDFDFQNDQAVEICKNEAEQALGNDGRILLRASGTEPLIRVMVEGKDPQQIEYWAEKIAGTIQQQAVASTVGH
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GOT1_ARATH
Sequence: MASLEMNDLKKIGLGLTGFGVFFTFLGVIFVFDKGLIAMGNILFLAGVTLTIGINPAIQFFTKRQNFKGTISFGLGFLLVVFGWPIFGLLLESYGFLVLFSGFWPTLAVFLQRIPLLGWLLQQPYIRSLLDRYRGRRVPV
What is the function of this protein?
May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
What are the official names of this protein?
Vesicle transport protein GOT1, Golgi transport 1.
What is the protein family that this protein belongs to?
Belongs to the GOT1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: IF3_CLOTE
Sequence: MNIIKKGFLMNEEIREKEVRVIAEDGEQLGVIPTSEALKRAEEKELDLVMIAPTGKPPVCKIMNYGKFIYEQTKKDKEAKKKQKVINVKEIRLSATIEEHDIGIKANNARKFLKAEDKVKVTVRFRGREMEHSNVVGNKILKTFLSKVEDVCVVEKPARLEGKNMTMVLAPRK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.