PharMolix/UniProtQA huggingface dataset:
Protein: Y920_TREPA
Sequence: MGVGRARLYFQYFKAKFLKRRVTPPVDYEEIVSEFWRADFSSTEHARWHAEAGDGYETARGAHGLTLHLRRKFLYAWSANPVFRYKDCVLTARIRFLPGTHPPGEARALPNSEQPEVPASLDSTSRPACLPEAVAVDPSAMGEAVPERAGTCAAGLLFRYLNESTFYALLVSDGGWLRLDAVVNNTPLPLLGWTDTGASDEVRVLSLIAVGTSFTLCVDDQWIAQIEDDTIQAAGKVCFAAQNWGVHAHRSFELSAFSLESQPFMVETACLRANEPARIPASAHLRLAESLYAMGRAACARAEMKKLKAKCTFGLREYLLAGDIACAQHLYDEAEEAFNAALVQDPHCMRALLALGGALYQQNAYEKLAHLLATHRVVAERDAFLSNLCGHLALAQNRHEDAAAAYQRAFRLDPHQGLFALHAAQELSLLGEKEQAIQAYLHAARLFLAQESYADLERVVLALRRLDPERTEVRSIAGKLYYATGRHRQAHTQFDALCRAGSADATVWYLYGLLLREAQGTHEHDAPAAAACEQRARDAFQRACALAPDCALYHFKYAESLFLSEKDCDEPLARALALDPDNGWLHNLCAQKALREQNFDAAAQSLQRARALLPHELVVLENYIELQRQRGALACCVPLFEVETQRADAAVIAQRGQAFHLLANAFYADGCYEHAAPWYDKALREEPQNVQMLVHKAENSIKLHLLHEADALLVKALDIQLTAHVYTLIALVAAQLGDFPRAELTLQEACTLWPQCTEVRIELIHLYLTMQDRQQAATQWNILVQKEDSDRVRALHALIFEEKPPAPQE
What are the official names of this protein?
TPR repeat-containing protein TP_0920.
Protein: RUTA_CROS8
Sequence: MPTFELNKAIVQKAEQQQFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMASTIDSISGGRFGVNLVTGWQKPEYEQMGLWPGDDYFSRRYDYLTEYVHVLRDLWDTGRSDFKGDYFTMNDCRVSPRPQQPMKVICAGQSDAGMAFSAQHADYNFCFGKGVNTPAAFAPTAARMKAAAEKAGRDVGSYVLFMVIADETDEAARAKWEHYKAGADEEALSWLTEQSQKDTRSGADTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVAAVPGTEGVLLTFDDFLTGIDAFGEHIQPLMRCRDHLRVTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: RUVA_BEUC1
Sequence: MIALVQGRVAAIGLDAVVVVVGGVGMRVLATPATLAGLRVEADCELHTSLVVREDSLTLFGFADADERDVFELVQTVSGVGPRLALAMLAVHTPDGLRRAVAQEDLAALVRVPGIGRKGASRIVLELGDRLGPAQGAAPAAPVAVDDGADVVDALVGLGWPVRQAQDAVRGVLEDADGTAPDAAGLLRAALRSLAGDARG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TAL_SHEB9
Sequence: MANTLEQLKLYTTIVADTGDIEAIKRYQPEDATTNPSLILKAAQIPEYESLIDNAIDWAKSQSDDLAQQLDDASDKLAVNIGVEILKLVPGRISTEVDARLSFDKEQSIAKAHKLVRLYKEAGVDKSRILIKLASTWEGICAARELEKEGINCNLTLLFSFAQARACAEAGAYLISPFVGRILDWYKKDTGKDYDAVNDPGVISVTEIYNYYKQHGFNTVVMGASFRNIGEIIELAGCDRLTIGPSLLEELANSQVDITPKLVAATSTVAAEAPLTEAQFRWDFNQDPMAVDKLAEGIRNFAIDQGKLEVMLTAKLAN
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM4_ZYGRC
Sequence: MTEKPNHEELGSKSIFYDPEWNPKGLAPPGFKNVAYNPATFTRKQSSLQRHMLGINADLPEEKKRMNKNGRE
What are the official names of this protein?
Altered inheritance of mitochondria protein 4.
What is the protein family that this protein belongs to?
Belongs to the AIM4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLB1_ARTBC
Sequence: MMFIPATLGTFVLASLLPATVGAGIPNAAADVAVRALPNAPDGYAPAEVDCPSTKPAVRSAAKLSQQEQDWLKKRRMKTTGAMADFFSRVKIEGFDAVAYLVGNADNVAKLPNVAIAVSGGGYRALMNGAGALKAFDSRTDNSTEPGQLGGLLQSATYLSGLSGGGWLLGSMYVNNDSTITELQKGGSNSLWKFNRSILEGPDDGSSGVVDTAEYYKEMIKEISRKKAAGFETSITDIWGRALSYQLINAPKGGPAYTWSSISQNSKFQSGDVPFPLLVADGRNPGEKLIGGNATIFEFNPYEFGTWDPTIFGFVPTQYIGSKFEAGTLPSDEKCVRGMDNAGFIMGTSSSLFNQFALHLDSQDLPKVVKDSLRDFLSSLDEANNDIAEYKPNPFFGYAKSTSPFAGVKSLPVVDGGEDKQNIPFHPLIQPARHVDVIFAIDSSADTELAWPNGDSIIATYQRSLNSTGIANGTSFPAIPDNNTFINLGLNHNPTFFGCDSSNTTNPTPLIVYIPNSPYVTHSNVSTFNLKYNTTQRDAIILNGYNVATMANATRDGNWPTCVGCAMLSRSLERTKTAVPDACKQCFKMYCWDGTLNSTKPDVYDPKLFLTEVDLQSAAKGLHASGKLSLVAAVVTLLSILLV
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids (By similarity).  Phospholipase B may well contribute to pathogenicity by abetting the fungus in damaging host cell membranes (By similarity).
What are the official names of this protein?
Lysophospholipase ARB_05919, Phospholipase B.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL15_ACIBC
Sequence: MTLRLNELAPAEGAKREHRRLGRGIGSGVGKTGGRGIKGQKSRKSGGVRPGFEGGQTAIYRRLPKFGFTSQIALKTAEVRLSELSKVEGDIVSLETLKAANVVRRDQIRARIVLSGEITRAFTVQGVALTKGAKAAIEAAGGKVEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RR7_HYDCA
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRALKKIQQKTETNPLSVLRQAICGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLWASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KBTB2_PONAB
Sequence: MSTQDERQINTEYAVSLLEQLKQFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAATLQIIITYAYTGNLAMNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQDAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVAQGLYKSMPKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSPPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRIKPSLVCCEGHIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVMTLNLMYCYFPRSDSWVEMAMRQTSRSFASAAAFGDKIFYIGGLHIATNSGIRLPSGTVDGSSVTVEIYDVNKNEWKMAANIPAKRYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDRWSLRQHISERVLWDLGRDFRCTVGKLYPSCLEESPWKPPTYLFSTDGTEEFELDGEMVALPPV
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of the insulin signaling pathway, modulating insulin sensitivity by limiting PIK3R1/p85alpha abundance in adipocytes.  Targets PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase (PI3K), for 'Lys-48'-linked polyubiquitination and proteasome-mediated degradation.
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 2.
Protein: PYRG_METB6
Sequence: MKYIFVTGGVMSGLGKGITAASVGRILKNRGYRVTAVKIDPYLNIDAGTMNPAQHGEVFVLKDGGEVDLDLGNYERFLDIELTSSHNITTGKVYRTVIEKERRGDFLGETVQIIPHITDQIKTCIRQAAEETFPDGTKADVCLVEVGGTVGDIESMPFLEAVRQMRGELDEHDYVLVHVTLVPEDAMGDLKTKPTQHSVKALRELGLHADIIVCRSERVVGANTKRKISAFCDLPLSAVISAATARDTYEVPMEMEKEGIADVLSTHLGLEKKETDPSWYRLVTKEYTNRVTVAIVSKYGIEDVYISIKEALKHAGRALSTEVKIVWLDAERYEPCSLKDYDGILIPGGFGKRGIEGKIGAIRFARENKVPFLGLCLGFQLATIEFARHKCGIADATSEEFGEGSHVIALLPEQESVTELGGTMRLGDYTSDIRDKTLAMKLYGKSQIIERHRHRYEVNPHYIEKLEKEGLVFSATNKNRMECLELPGHPFFFATQFHPEFKSRPTRPSPPYLGFVEACRANKRTT
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NRDI_ECODH
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: DENR_XENTR
Sequence: MASIAIENAEPVPSDCKGDLKISKFDGDLPLKVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPDEFSKLTLGISPKQETGTVEGQATSGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIELKDAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK
What is the function of this protein?
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon.  Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes.  Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).
What are the official names of this protein?
Density-regulated protein, DRP.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
Protein: ODPA_PANTR
Sequence: MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSGPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RUTE_ECOLI
Sequence: MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFTGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.  RutE is apparently supplemented by YdfG.  Required in vivo, but not in vitro in pyrimidine nitrogen degradation.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: KPYK1_ECO57
Sequence: MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
What are the official names of this protein?
Pyruvate kinase I, PK-1.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: HISZ_PSE14
Sequence: MATVDRWLLPDGIEEVLPPEAACIEVARRQVLDLFQSWGYEFVVTPHIEYLESLLTGAGSDLDLRTFKVIDPQSGRQMGFRADITPQVARIDAHTLKREGPSRLCYAGSVLHAQPRALSSSRSPIQLGAELYGDASPSSDVEVISLMLAMLQLADVPDVHMDLGHVGIYRGLARAAGLSGEVEQQLFDALQRKAIDEVVALTADLPQELASMLRALVDLCGGREVLDAARDRLAGAPAPVLAALNDLLAIAERLAARFPQLPLYFDLGELRGYHYHTGVVFAVFVPGVGQSIAQGGRYDDIGADFGRARPATGFSTDLKTLVTLGQAEIVLPSGGIWVPDSTDAALWQQVCQLRSEGQRVVQALPGQQASAAREADCDRQLIQHGEHWQVMPLAS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_STRA5
Sequence: MPKKTDTPAYKPSIYSLTRDELIAWAIEHGEKKFRASQIWDWLYKKRVQSFDEMTNISKDFIALLNENFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLNNGEITAQIMLVQKYFDERGQGERVSHIVVMGIGEPFDNYTNVLKFLRTVNDDNGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVSLHAPNNDLRSSIMRINRSFPLEKLFAAIEYYIETTNRRVTFEYIMLNGVNDTPENAQELADLTKKIRKLSYVNLIPYNPVSEHDQYSRSPKERVEAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSNTMKRDRQKAKVGQ
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDH8_RAT
Sequence: MSPVKRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSGDTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGQSPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSESAPVGTRIPLEVPVDEDVGANGLQSVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQASYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFTFGARTPPEARHLFRLDPRSGRLTLAGQVDYERQDTYELDVRAQDRGPGPRTATCKVIVRIRDVNDNAPDISITPLAAPGAPATSPFAAAAAAAALGGADAASSAGSGTQETGVTSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDENDNAPLFTKPVYEVSVRENNPPGAYLATVAARDPDLGRNGQVTYRLVEAEVGRSGEAVSTYVSVDPATGAIYALRSFDYETLRQLDVRVQASDGGSPQLSSNALVQVRVLDQNDHSPVLVHPAPANGSLEVAVPGRSTKDTAVARIQARDADEGANGELAFDLLQQEPREAFSIGRHTGEIVLTGDLSQEPPGRVFKALLVISDGGRPPLTTTATVSFVVTAGGGSAVPASAGSPEHFRPPGSRLAPSGPSLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEVRKGGALREERPGAAGGGASAPGSPDETARGTGPRPNMFDVLTFPGSGKAPFGSPAADAPPPAVAAAEVPGSEGGSATGESACHFEGQQRLRGAHAEPYSASPGFGKEPAPPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCAGPNTHPPPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYESPPGGRYVSPKKGTNENV
What is the function of this protein?
Calcium-dependent cell-adhesion protein.  May play a role in activity-induced synaptic reorganization underlying long term memory.  Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway.  In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis.
What are the official names of this protein?
Protocadherin-8, Activity-regulated cadherin-like protein, Arcadlin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Presynaptic cell membrane. Postsynaptic cell membrane. Note=Also expressed in the cell bodies of neurons of the hippocampus and cortex. Localized to excitatory, but not with inhibitory, synapses.
Protein: LCAT_GERGM
Sequence: TIWLDLNMFLSLGVDCWIDNTRVVYNRSSGRVSNAPGVEIRVPGFGKTYSVEYLDDNKLAEYMHTLVQNLVNNGYVRDETVRAAPYDWRLEPSQQDDYYQKLAGLIEEMYAAYGKPVFLIGHSLGCLHVLYFLLRQGIPIMSSIKLREEQRITTTSPWMFPDRDVWPEDHVFISTPEFNYTGQDFERFFSDLHFEEGWYMWLQSRDLLAGLPAPGVDVYCLYGVGLPTPHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQPVHLLPMNGTEHLNMVFSNKT
What is the function of this protein?
Central enzyme in the extracellular metabolism of plasma lipoproteins.  Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs).  The cholesterol ester is then transported back to the liver.  Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines.  Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels.  Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins.  Required for remodeling high-density lipoprotein particles into their spherical forms (By similarity).
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma. Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (By similarity).
Protein: YOR4_BPSPP
Sequence: MRPNDWRKKNRIQQIEYKKNNLTKDDIELLEEIVKRAKRGEFVDFMFAASLNTPDDMVFVGYTDYMSIRNMSSSRQNHYYACMTP
What are the official names of this protein?
Uncharacterized 10.2 kDa protein in GP2-GP6 intergenic region, ORF 4.
What is the protein family that this protein belongs to?
To phage SP01 gene 46 protein.
Protein: RL29_AMOA5
Sequence: MKYAEISSLAIEELKEKIKIEQENLRKLKFAHTISPIENPTKIKNTRRLIARLETALNVKGS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL14_MICLU
Sequence: MIQQESRLKVADNTGAKEILTIRVLGGSGRRYAGIGDTIVATVKDAIPGGNVKKAHVVKAVVVRTRKQSRRPDGSYIKFDENAAVILKTDGEPRGTRIFGPVGRELRDKKFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RLMH_ANADF
Sequence: MRLRVVAVGRDRSGLYAPAIEEYAKRLGRYVKFELVEVPEARKHAGTAQARDEEAEALLAKLGPRERVIALDERGAEWTSVAFAERVRRWTEGGRDVALVIGGSDGLSRAVLDRAEETLALSRMTLAHRLARLVLVEQLYRAMTILRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_STAA2
Sequence: MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_BACMK
Sequence: MNEVVAKGKKAKEIARELVLKSTNQKNEALAAIADQMIVETAYILEENKRDIEEGKAKGFSDSLLDRLMLNEQRIIDMAEGIKQLIELRDPVGECVSAWERPNGLSIQEMRVPLGVVGMIYEARPNVTVDAATICLKTGNAVILRGSSSAINSNKAIVSVIHRALKQTSLPPESVQLIEDTTRDSAKQLFTLNEYLDVLIPRGGKQLIDTVVREASVPVLETGAGNCHIFIDETADKQMAFNIIINAKTQRPSVCNAIETIVLHEKWAQQFGSELFSSLKERGVELRGDSKSLAIDSSIALASEEDWETEFLSLTLAVKVVSTTEEAIHHINTYGSMHSEAIITENEENVSKFFTSVDAAALYHNASTRFTDGSEFGFGAEIGISTQKLHVRGPMGLPALTSTKYVIRGNGQIRR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_RHOPB
Sequence: MSVQSAIKRKTAPEIRARKGGDPVVMLTSYHAHTAALVDRYCDVILVGDSLGNVMHGFETTVPVTLDMMILQGRAVMRGSKEALVVVDMPFGSYEASKEQAFHSAVRIMKESLCGAVKLEGGVKMAETIRFLSERGVPVMGHIGLTPQSINTLGSFRAQGREESNWAPIEADARAVAEAGAFSVVIEAVAEPLARKITADIAIPTIGIGASAACDGQVLVLEDMLGLSPWAPKFVKRFGDLGPGIEAAIKDYADEVRSRAFPGPEHVYGMKAKS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_PEDPA
Sequence: MLDLKMIRNHVEDVKAKLATRGVKPEAIDDLLAKDNERRELIVKSENLKKLRNEVSDQISQLKRNKEDANDKIQEMRKVSQDIKGLDEQLENIAEEVESKAAHLPNLPHEDVPVSLTEEGSVEQRRNGTPRTFDFTPKAHWEIGEELGILDFERAAKVAGSRFVYYVGDGARLERAVYNFFLDQNNAAGFTEEITPYMVNDASMFGTGQFPKFKETHAGYEVKDEGLTLIPTAEVPLVNYYRDEIIDEEKLPISVTALSPAFRSEAGSAGRDTRGLIRMHQFNKVEMVKIAKPEQSWNELEKLTTHAETLLQKLGLPYRVITLTTGDMSFTAAKTYDLEVWIPAQDKYREISSCSNCTDFQARRAHIRFRDENGKLQYVHTLNGSGLAVGRTVAAILENYQNEDGTVNVPEALVPYMQGTTVIGKK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_PSEAB
Sequence: METVVGLTAIAVALLIGLGALGTAIGFGLLGGKFLEGAARQPEMVPMLQVKMFIVAGLLDAVTMIGVGIALFFTFANPFVGQIAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MCPI_HIRME
Sequence: MFLLVFLCCLHLVISSHTPDESFLCYQPDQVCCFICRGAAPLPSEGECNPHPTAPWCREGAVEWVPYSTGQCRTTCIPYVE
What is the function of this protein?
Tightly binding, competitive inhibitor of different types of pancreatic-like carboxypeptidases.
What are the official names of this protein?
Metallocarboxypeptidase inhibitor, Leech carboxypeptidase inhibitor, LCI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I46 family.