PharMolix/UniProtQA huggingface dataset:
Protein: XCT_HUMAN
Sequence: MVRKPVVSTISKGGYLQGNVNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEEDKL
What is the function of this protein?
Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane (PubMed:15151999, PubMed:34880232, PubMed:35352032, PubMed:35245456, PubMed:11417227, PubMed:14722095, PubMed:11133847).  Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress (By similarity).  The transport is sodium-independent, electroneutral with a stoichiometry of 1:1, and is drove by the high intracellular concentration of L-glutamate and the intracellular reduction of L-cystine (PubMed:11417227, PubMed:11133847).  In addition, mediates the import of L-kynurenine leading to anti-ferroptotic signaling propagation required to maintain L-cystine and glutathione homeostasis (PubMed:35245456).  Moreover, mediates N-acetyl-L-cysteine uptake into the placenta leading to subsequently down-regulation of pathways associated with oxidative stress, inflammation and apoptosis (PubMed:34120018).  In vitro can also transport L-aspartate (PubMed:11417227).  May participate in astrocyte and meningeal cell proliferation during development and can provide neuroprotection by promoting glutathione synthesis and delivery from non-neuronal cells such as astrocytes and meningeal cells to immature neurons (By similarity).  Controls the production of pheomelanin pigment directly (By similarity).
What are the official names of this protein?
Cystine/glutamate transporter, Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, Solute carrier family 7 member 11, xCT.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: GB_HHV1P
Sequence: MRQGAPARGCRWFVVWALLGLTLGVLVASAAPSSPGTPGVAAATQAANGGPATPAPPALGAAPTGDPKPKKNKKPKNPTPPRPAGDNATVAAGHATLREHLRDIKAENTDANFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRYSQFMGIFEDRAPVPFEEVIDKINAKGVCRSTAKYVRNNLETTAFHRDDHETDMELKPANAATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTSYAADRFKQVDGFYARDLTTKARATAPTTRNLLTTPKFTVAWDWVPKRPSVCTMTKWQEVDEMLRSEYGGSFRFSSDAISTTFTTNLTEYPLSRVDLGDCIGKDARDAMDRIFARRYNATHIKVGQPQYYLANGGFLIAYQPLLSNTLAELYVREHLREQSRKPPNPTPPPPGASANASVERIKTTSSIEFARLQFTYNHIQRHVNDMLGRVAIAWCELQNHELTLWNEARKLNPNAIASATVGRRVSARMLGDVMAVSTCVPVAADNVIVQNSMRISSRPGACYSRPLVSFRYEDQGPLVEGQLGENNELRLTRDAIEPCTVGHRRYFTFGGGYVYFEESAYSHQLSRADITTVSTFIDLNITMLEDHEFVPLEVYTRHEIKDSGLLDYTEVQRRNQLHDLRFADIDTVIHADANAAMFAGLGAFFEGMGDLGRAVGKVVMGIVGGVVSAVSGVSSFMSNPFGALAVGLLVLAGLAAAFFAFRYVMRLQSNPMKALYPLTTKELKNPTNPDASGEGEEGGDFDEAKLAEAREMIRYMALVSAMERTEHKAKKKGTSALLSAKVTDMVMRKRRNTNYTQVPNKDGDADEDDL
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: CH60_NEORS
Sequence: MANEVISGEQLQKVIRDAADLVVSSAGVTLGPEGRPVIMSKSYGGPEVTKDGYKVINNLKPEDEKIAKIVELLNQATSQANEKAGDGTTTATILVGNMIKNAHKHIAAQRSRTKLKSGMKRARDEVVKYIQSVAKKINSEEEIAQVGSISANGNSEIGNKIAEAMNKVGKEGVITVEEGKGLDEFSVSVVQGMVFDRGYVSPYFITNPEKMIVEFDNPYVLLANKKLSSIQPMVPLLETIVRSNRAVVIIAEDVEGEALTSLVLSKMRGSLKACAVKAPGFGDRRSEMLEDIRILTGAKTLVSDDLGVTVESLTVEDLGTAKSIIISKDSTTIVDGGGEKTSIDARVKQIKTQIDKTTSDYDKEKLQERLAKLAGGVAVLKVGGATEVEVKERKDRVEDALHATRAAVEEGIVPGGGATLLSAIAVLEKLSSDDDDEQAGINIVKSALKAPISQIVENAGEDASVITYNLLESKDPNRIFDARELKYVDAFKAGIIDPAKVVRVALESAVSVASVLVTTEALIVDLPTKDNGSPSMMPGGGMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BRUO2
Sequence: MSRRHKAEKREINPDPKFGDLVITKFMNAVMLHGKKSVAESIVYGALDAIEAKAKSEPVALFHQALDNVAPHIEVRSRRVGGATYQVPVDVRPERRQALAIRWLINAARGRNETTMVDRLSGELLDAANNRGSAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MSMF_STRMU
Sequence: MTIRKVLNKYWGWTFLIVPLILQVVFFYFPMFQGAFYSFTNWTGLTYNFDFVGINNYKILMTDGKFMKAIGFTLVLTLALIVGEIVLGIIIARALNAKIKGKTFFRAWFFFPAVLSGLTVSLIFKQVFNYGLPAVGSALGIKFLETSMLGTANGAVIASIFVLLWQGVAMPIILFLSGLQSIPSEIVEAAAIDGADSKQTFWSVELPYLLPSISMVFIMALKAGLTAFDQIFALTGGGPNNSTTSLGLLVYNYAFKSNQYGYANAIALILFIIIGIVSVLQIKLSKKFEV
What is the function of this protein?
Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose.
What are the official names of this protein?
Multiple sugar-binding transport system permease protein MsmF.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RHMD_VEREI
Sequence: MGMPFIKHVRAFTVRGGGADYHDQGGGHWIDDHIATPMSKYPEYRQSRQSFGINVLGTLVVEIEASDGTVGFSVTTGGDLGCFIVEKHLARFLEGARVTDIEKMWDQMYSATLYYGRKGIVINTISGVDLALWDLLAKIRKEPVHALLGGPVRDELIFYATGARPDLARQMGFIGGKMPLHHAPAEREEGLAKNLDMIGDMRSKVGKDFWLMLDCWMSLDVEYATRLATAARNEHGLKWIEEALSPDDYWGYAELRRNVPRGMLVTTGEHEATRWGFRLLLEMGCCDIIQPDVGWCGGITELIKISNLADAHGKLVVPHGSSVYSYHFVITRQNSPFAEFLMMAPKADEVVPMFNPQLLDEPVPVNGRIKASALDAPGFGVRLNPDIALHRPYPRQAA
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
Protein: GLPK_ECO45
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: FPG_BORA1
Sequence: MPELPEVETTRRGIDPVITGQTLRRLVVREPRMRWPIPADLPSLLTDRPVLATGRRGKYLLLRFEHGVQIVHLGMSGSLRRVAMDEAPRKHDHVDWVFDHAILRLHDPRRFGAVLWHPNTDGPVEAHPLLIGLGIEPFDPRFDGKWLHDHFRDKRVAVKQALLAGHAVVGVGNIYASECLFRAGIDPRTPAGKLSRPRCERLAQAVRATLADALASGGSTLRDYVGASGEPGAYFAIHAAVYERAGLACRVCGTPIRRLVQGQRATYFCPHCQKR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: ATP6_PONPY
Sequence: MNEDLFTPFTTPTVLGLPAAILVILFPPLLVPTSKHFINNRLITTQQWLIRLTLKQMMITHNTKGRTWSLMLTSLIIFIASTNLLGLFPYSFTPTTQLSMNLAMAIPLWASTVAMGLRFKAKISLAHLLPQGTPTPLIPMLIIIETISLFIQPLALAVRLTANITAGHLLMHLIGSATLTMLTINLPLTLITLTILTLLTILEIAVALIQAYVFTLLVSLYLHDNS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPB8A_ARATH
Sequence: MASNIILFEDIFVVDQLDPDGKKFDKVTRVQATSHNLEMFMHLDVNTEVYPLAVGDKFTLALAPTLNLDGTPDTGYFTPGAKKTLADKYEYIMHGKLYKISERDGKTPKAELYVSFGGLLMLLKGDPAHISHFELDQRLFLLMRKL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  Component of RNA polymerase V which mediates RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.
What are the official names of this protein?
DNA-directed RNA polymerases II and V subunit 8A, RNA polymerase I, II and III 16.5 kDa subunit, AtRPABC16.5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y453_METAC
Sequence: MKILLFICGEGLGHTSRCLALGKEFLAAGHEVSFGAYGYSRELVRKTGYSAWEIQPEIRLIGETGIFDIGKSIKETLRNLSPVGFRKLLKLIEVLEPDVVLSDGYYSGILAARSRKVPVYFIGHQFNMEEFFQKKGPLLAVAGKLVRRFYNYIFSSVDGIMVPDYPLPYSVNRRNFTIPRALNPNIFFSGPLIRSRYREVEAKAFRHPNVLSTIGAFGYRAAIFRKVLEAAKLDPDIHYTFIAGPGIVPEQFPEIPENVEFTGFTDNPFPYYRGSDLVITAGGHGTIMESLAFGLPVLSFPDEKHTEQENNATVLEDAGYGKRMSYLTRPEVILACIREVLEDENYRRKTRRLMELAEVLDGPAAVRKLLEEKFGERSAGKENSKEET
What are the official names of this protein?
Uncharacterized glycosyltransferase MA_0453.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
Protein: PYRR_DESOH
Sequence: MEMEKRTPVLDGQGINTVLIRLAREIIQRHTNLEPLVIIGVHTRGVHLARRLADTIAEINGRAIPTGDIDITLYRDDWTKIGYSPVVQSTQIGFPIDDKTVILVDDVLFTGRTTRAALDALTDFGRPAKVELAVLVDREGMRELPIQADYVGMFVKTDKAEMVNVLLSETDGEDAVVVNTP
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: Y399_BORBU
Sequence: MKKEFIMLLLLLQTIMNLNSINTNTSTSIVKELQKNLYIFNSKEYQKDKDTLNEFINSININDKEILQSLEKIKNELFIISVFFNNKKGILIALNLGAEINFKYKISPISISIINNEFEITKILIDYGISLNQIDDTGYSPIFWAIYTNNEKIFEFLKESGADLSFTLKNRKTPMQAAIETENIKLIKSLEKKKIYIDDNFKKKLKKLKNKEIVRILVK
What are the official names of this protein?
Putative ankyrin repeat protein BB_0399.
Protein: PVK2_MANKU
Sequence: SGLQFAVLDGQGFLPFSRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
CAPA-Periviscerokinin-2, CAPA-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MCRB_STRLA
Sequence: MTSSDGSDLTTLVNVGRSVARYFERIGITEIAQLRDRDPVELYERMSAAFGQRLDPCLLDTVMSAVDQAEGLPARPWWHYTPERKRLLAGEGHDRAGGTAGEGTA
What is the function of this protein?
Involved in mitomycin resistance.  May operate with McrA or may be a type of transcriptional activator protein.
What are the official names of this protein?
Mitomycin resistance protein McrB.
Protein: PSBM_THEVB
Sequence: MEVNQLGLIATALFVLVPSVFLIILYVQTESQQKSS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.  Probably involved in dimerization of PSII; at the monomer-monomer interface the only protein-protein contacts observed are between the 2 PsbM subunits.  Lipids, chlorophylls and carotenoids contribute strongly to PSII dimerization.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RT25_KLULA
Sequence: MKVQQEAVNVLERTSAYLKSGILKKTPAWYNVIAKVPPTKKFARTPQLTHPMNGKSRTALPDYSNWKANSSGLYKTRPNSLEKKDGASKLYQSPKLVYIEDKLRKLFFQQHPWELSRPKILVENTLETQEYDWSHIQQLGKPLDGESVVQRTLFLLKSGEKKELIDAYDQARFEFYRLRIQQEIQDQVAQEEAEMFGSVFHTTSIEYGIAKEQKVIDTWKRKALQQAELMAARASSPSASWTNETEEEQKPIDQDVEEIQL
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL28_HAHCH
Sequence: MSRVCQVTGKSPITGNNVSHANNKTKRRFLPNLQTHRFWVENEKRFVKLRVSTKGMRIIDKVGIDKVLSDIRARGGKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: COAA_COXBU
Sequence: MTVKPELNEITPYLQFNRQQWGNFRKDTPLTLTESDLDKLQGQIEIVSLKEVTEIYLPLSRLLSFYVTARQTLQQATYQFLGKPEPKVPYIIGIAGSVAVGKSTTSRVLKALLSRWPDHPNVEVITTDGFLYSNAKLEKQGLMKRKGFPESYDMPSLLRVLNAIKSGQRNVRIPVYSHHYYDIVRGQYEIVDQPDIVILEGLNILQTGVRKTLQQLQVFVSDFFDFSLFVDAQAQVIQKWYIDRVLSFWRTTFKDPHSYFHYLTQMSETEVAAFAKHVWNEINKVNLMENILPYKNRAQLILEKAADHSIQKVYLRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRNQL_STAAB
Sequence: MNKNTWVIGFTLFAMFFGAGNLIFPPNLGLDSGQFFWPAILAFVLTGIDLPLLGVIVGALDKEGYIGALNKISPKFSILFLIIIYLTIGPLFAIPRTASTSFEMTITPIIHSNSSIALFIFTIIYFIVVLYICLNPSKLIDRIGSLLTPLLLITILAMIIKGYLDFSGNTAGKGNEALYHSNFSSFAEGFTQGYLTMDAIAAIAFSMIVVNAVKLTGITKTNQIFKQTLTAGLIAAVALIFIYISLGYIGNHMPVSDMTLDQLKSKDRNIGTYLLTTMASTGFGSFGKYLLGIIVALACLTTACGLIGAVSEYFHRIVPKVSYKAFVLVFILMSFIIANQGLNAVISMSIPVLSIVYPVAITVVLLILIAKFIPTKRISQQIPVIIVFILSIFSVISKLGWLKINFIESLPLRAYSLEWFPVAIIATILGYLVGIFVKQDPIKYQQE
What is the function of this protein?
Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine), which is coupled to a proton motive force (Potential).  Contributes to NaCl tolerance (By similarity).
What are the official names of this protein?
Putative branched-chain amino acid carrier protein SAB1263c.
What is the protein family that this protein belongs to?
Belongs to the branched chain amino acid transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASSY_SHIF8
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGLPQVENMENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPH1_SALT1
Sequence: MFNIRNTQPSVSMQAIAGAAAPEASPEEIVWEKIQVFFPQENYEEAQQCLAELCHPARGMLPDHISSQFARLKALTFPAWEENIQCNRDGINQFCILDAGSKEILSITLDDAGNYTVNCQGYSEAHDFIMDTEPGEECTEFAEGASGTSLRPATTVSQKAAEYDAVWSKWERDAPAGESPGRAAVVQEMRDCLNNGNPVLNVGASGLTTLPDRLPPHITTLVIPDNNLTSLPELPEGLRELEVSGNLQLTSLPSLPQGLQKLWAYNNWLASLPTLPPGLGDLAVSNNQLTSLPEMPPALRELRVSGNNLTSLPALPSGLQKLWAYNNRLTSLPEMSPGLQELDVSHNQLTRLPQSLTGLSSAARVYLDGNPLSVRTLQALRDIIGHSGIRIHFDMAGPSVPREARALHLAVADWLTSAREGEAAQADRWQAFGLEDNAAAFSLVLDRLRETENFKKDAGFKAQISSWLTQLAEDAALRAKTFAMATEATSTCEDRVTHALHQMNNVQLVHNAEKGEYDNNLQGLVSTGREMFRLATLEQIAREKAGTLALVDDVEVYLAFQNKLKESLELTSVTSEMRFFDVSGVTVSDLQAAELQVKTAENSGFSKWILQWGPLHSVLERKVPERFNALREKQISDYEDTYRKLYDEVLKSSGLVDDTDAERTIGVSAMDSAKKEFLDGLRALVDEVLGSYLTARWRLN
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues (PubMed:10564523, PubMed:18005683, PubMed:16611232, PubMed:24248594).  This protein is an E3 ubiquitin-protein ligase that interferes with the host's ubiquitination pathway and targets host proteins for proteasomal degradation (PubMed:10564523, PubMed:18005683, PubMed:16611232, PubMed:24248594).  Can ubiquitinate ubiquitin, giving rise to polyubiquitin chains (in vitro) (PubMed:18005683).  Polyubiquitinates host PKN1, leading to its proteasomal degradation (PubMed:16611232, PubMed:24248594).  Down-modulates production of host pro-inflammatory cytokines by inhibiting NF-kappa-B-dependent gene expression; this depends only partially on its E3 ubiquitin-protein ligase activity (PubMed:12819095).
What are the official names of this protein?
E3 ubiquitin-protein ligase SspH1, RING-type E3 ubiquitin transferase SspH1, Salmonella secreted protein H1, Secreted effector protein SspH1.
What is the protein family that this protein belongs to?
Belongs to the LRR-containing bacterial E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into the host cytoplasm. Localizes predominantly to the host nucleus.
Protein: MYG_GOBGI
Sequence: MADFDMVLKCWGPVEADYTTHGSLVLTRLFTEHPETLKLFPKFAGIAHGDLAGDAGVSAHGATVLNKLGDLLKARGAHAALLKPLSSSHATKHKIPIINFKLIAEVIGKVMEEKAGLDAAGQTALRNVMAVIIADMEADYKELGFTE
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YJ08_YEAST
Sequence: MTTNSRLCPSSPSSSLIKHLTTSGGPSTSLTIMLSVIAIRILPAGMRNWIRQALGSLLFASFLLLSSFHYPITLTLVPVYHESLVKPTSASFGGIRLSQLTMIMERRATPTCQDPSLTEV
What are the official names of this protein?
Putative uncharacterized protein YJR038C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRPBP_PSEAE
Sequence: MRPRSALRYSLLLLALAASAAIQAQPKTLAVCTEAAPEGFDPARYTSGYTFDASAHPLYNALAAFAPGSATVIPALAESWDVSADGLVYTFRLRQGVKFHSTDYFKPTREFDADDVLFSFQRMLDPQHPAHDLSPSGYPYADAMQLRDIIERIEKIDEHQVRFVLKHPEAPFLADLAMPFGSILSAEYAGQLIARGKGDELNSKPIGTGPFVFTRYRKDAQVRYAANPDYWKGKPAIDHLVLAITLDPNVRVQRLRRNECQIALTPKPEDVAALRQDPQLTVLEEAAMITSHAAINTRHEPFDDPRVRRAIAMGFNKSSYLKIVFGDQARPAIGPYPPMLLGYDDSIRDWPYDPERAKALLKEAGVTPDTPLNLYISTGSGPGGNPARVAQLIQSDLAAIGIRVNIRQFEWGEMVKRTKAGEHDMMLYSWIGDNGDPDNFLTHNLGCASVESGENRARWCDKGFDEAIRKARMSNDESQRVALYKEAQRIFHEQMPWLPLAHPLMFDAQRKNVSGYRMSPMSARDFSRVKLD
What is the function of this protein?
Binds different tripeptides.  Probably recognizes specifically tripeptides composed exclusively of L-amino acids.
What are the official names of this protein?
Tripeptide-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TATA_MYCSJ
Sequence: MGGLQPWHWVIVIAVFVLLFGAKKLPDAARSLGKSMRIFKSEIKEMQSEGKSDNPPATPITSERVDTNPTAEQPDKRSA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.