PharMolix/UniProtQA huggingface dataset:
Protein: TRM5_NEUCR
Sequence: MSQSEKENQGSGEGKTQDMAIFSPPVVRSGAGALNRALFTKTVNLAAAAVNDNRLISKYRKELEHSKELLRQDRLSPIVNHPDKALADQGKKCLLLSPNVKAPEPETWGAALKEGVQKKELSVIPYELQLNYDYWTYHDIITSILPEELHDDIPSGFNTAGHVAHMNLRERYIPYKKVIAEVILDKTTNIRTVINKVDNVGAESEFRTFQYEVLAGPDDMQVQVTENACSFEFDYSKVYWNSKLEAEHRRLINMFEPGEVVCDVMAGIGPFAVPAGKKGVFVWANDMNPESNKYMQVAINRNKVSQYVRPICEDGRTFIHHAADSVLEAHKNGEHVLIAPKPPSRAKKAPKPEPKRVDIPPTISHFVMNLPATAIEFLGCYRGVYAGHEDLFSAESGRKLPLVHVHCFSFKADDETPLNDICERITKYLGFPVKPGNPDVEGEVAVHDVRDVAPAKRMFCASFRIPREVAFAERV
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: RUVC_YERPS
Sequence: MAIVLGIDPGSRVTGYGVIRQQGRQLTYLGSGCIRTVVDDMPTRLKLIYAGVTEIITQFQPDFFAIEQVFMAKNPDSALKLGQARGAAIVAAVNLNLPVSEYAARQVKQTVVGTGAAEKSQVQHMVRSLLKLPANPQADAADALAIAITHCHLSQNTLRLGNDQMTLSRGRIR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MURI_LEPIC
Sequence: MKEPLKIGLMDSGMGGLSVLKELLKYDSELEIVYYGDLKNSPYGEKDASEVLELVRSVCNFLQKENVSAILLACNTATSAAAQTLRKEFSIPIFGMEPAIKPAILQNPGKKVALLATPVTQREEKLQRLKSELKAEELVLSISCPGLAGLVDQGDFDKAEKYLRPILANLQEQDVENLVLGCTHYVFLKQIILKNFPNVKIYDGNSGTIKHLLNSLQVPRVILNGSQNNRSIYKLILNSEKEFHFRLASKLLSLKE
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: NOXA1_RAT
Sequence: MSSLGDQIRDWHRGVLAVAREDWDSALCFFSDVREPLAKMYFNMGCVHLMAGDPEAALRAFDQAVTKDTCMAVGFLQRGVANFQLQRLQEAVSDFQLALAQLRGNAAIDYTQLGLDFKLQAWEVLYNMASVQCQAGLWTKAANTLVEAISKRPEGAQDTLEAAMDKVQKQVPLQLRQVPKGEVFQPPRRYLKHLEPMDFLGKAKVVASVIPDDHNSDIQPQQSSQVEQAGLQSSSPVCKRVLSTRGGHMSPGLWDSLLATGGPVPGPSEDSSSAEGTATKDPESLVTVTVQCHFTVPLKVPRGTDLSSFRTLLSQALLQQTQKGQFSYKARGEDRAWVPISTEDSLQSVWRNVPVSPRGLQLQCRGAWGRPVLYQVVAQYDYRAQRPEDLDFRQGDTVDVLCEVDEAWLEGHRDGRVGIFPKCFVVPAATCVEALPVPEPQPGEQH
What is the function of this protein?
Functions as an activator of NOX1, a superoxide-producing NADPH oxidase.  Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction.  May also activate CYBB/gp91phox and NOX3 (By similarity).
What are the official names of this protein?
NADPH oxidase activator 1.
What is the protein family that this protein belongs to?
Belongs to the NCF2/NOXA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1.
Protein: LPXK_ECOL5
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPIPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTGAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVAIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAIAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGH
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: GLO2_SYNSC
Sequence: MHSSLHALPVLQDNVIWIWVRGAEAVVIDPAVAPPVRAWLEKRQLSLAAVLQTHHHADHIGGTPELLQRWPEAEVIASADDRERIPFQTMPVRGGDHVTVLGETVEVMDVAAHTRAHIAFFLPNPKGAEIRPLLFCGDTLFSGGCGRLFEGSAEQMHQALQKLAELPEATQVCCAHEYTEANLQWAVAQQPNNTVLVERYREVRSLRAKGELSLPSSIGLERRTNLFMQASSAAELGFLRSHKDQWRPT
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: HIS4_PELUB
Sequence: MKIFPAIDIKDKKCVRLIKGDFNNKTEYEISPVDQAGKYKDHGFKNLHIVDLDGALTGETVNLDIIKEIVHKFDLKIEVGGGVRSIDSIEKYINAGVEKVILGSAAIKNKNFLKEACQKFPNKIALGLDAKDGYLSVSGWKENSNQLTLDFLKEVNDYGASRLIYTDINRDGTKESPNFEETTNVANVSNCPVIISGGVSSIDDIKKAKGLKNIEGIIVGKAIYDGDIKLEELVKELDA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IORF_CVRSD
Sequence: MESSRRPLGLTKPSADKIMEIEAEGISPSRLQLLSPIPGVWFPITLGFRALPNSRREKSSSLQVDKECLLPMESHLLSKRDIGIDTTVVLLKHLMGSRSNYSPDGIFTILGRAPMLEPVSETALRESSGLQIVRRIPTPLLTLLKGTQVAMRLFLLGLRPVRYCLRVSMLKAREGLHLLVDLVRGHNPVGQIIALEAVPTSASLPLL
What is the function of this protein?
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host.
What are the official names of this protein?
Protein I, Accessory protein N2, N internal ORF protein, IORF, Protein in nucleocapsid ORF.
What is the protein family that this protein belongs to?
Belongs to the coronavirus I protein family.
What are the subcellular locations of this protein?
Virion.
Protein: NUP50_CAEEL
Sequence: MNSLIPPPTSEQQMNMFRLRDKMSLLNAEFLKVINGYFTEKNHYDFSGTMKSYMDHVAQLKQIYKVDDDVAADMTVPRRTENSSESSGETVAPRKIAKAVRKNGTPKNPLNSTVFAASSPAATVASVPKFGDISVITKETPAPLAKTAEPLVAPAAPATARKRAIRGGGPLGGAESVVFKSGEDGQAATSSVKIPATTIKFPEPTKDFWTKKSDAPAAPSNSGSLFAFLGKDGDKPKETPKFSGFSFGKKPAEPSEEPKAADSTPKLTFGSPKEADLPKPASSLFGASPSKPLVFGGSSADSTTSAPKPFSALSTAASLFGSSSASTTTTATQPLSFGSSSTGGSSLFSGFAGLAQKAMENQNQAKPEGSGEDDEGEYVPPKVETVENQEPDAVLSSKVSVFKFTGKEYTKLGVGMLHIKDNDGKFSVLIRAATATGTVWLNSLCNKAMKATVVDAKGDRIRLTCPSSSTEMATMMIRFGTADGAKKFTDKILEVAV
What is the function of this protein?
Component of the nuclear pore complex (PubMed:24011592).  Plays a direct role in nuclear protein import (By similarity).  Required for anoxia-induced prophase arrest; may function in concert with cdk-1 to arrest prophase blastomeres in response to anoxia (PubMed:20053678).
What are the official names of this protein?
Nuclear pore complex protein npp-16, Nucleoporin npp-16.
Protein: S45A3_MOUSE
Sequence: MIQRLWASRLLRHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASDQWRGRYGRRRPFIWALSLGVLLSLFLIPRAGWLAGLLYPDTRPLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLGGCLGYLLPAIDWDTSVLAPYLGTQEECLFGLLTLIFLICMAATLFVTEEAVLGPPEPAEGLLVSAVSRRCCPCHVGLAFRNLGTLFPRLQQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGIRMGSLGLFLQCAISLVFSLVMDRLVQKFGTRSVYLASVMTFPVAAAATCLSHSVVVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDAGGSSGEDSQTTSFLPGPKPGALFPNGHVGSGSSGILAPPPALCGASACDVSMRVVVGEPPEARVVTGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSHSVTAYMVSAAGLGLVAIYFATQVVFDKNDLAKYSV
What is the function of this protein?
Proton-associated sucrose transporter.  May be able to transport also glucose and fructose.
What are the official names of this protein?
Solute carrier family 45 member 3, Prostate cancer-associated protein 6, Prostein.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EX7L_YERPG
Sequence: MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQVLVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPHPAKQVGVITSASGAALHDVLHVLQRRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHETDVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLLKLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLATLARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVTQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2846_MYCVP
Sequence: MSDVVSVRVKPGSKKGPLVETGPDGELTVYVRERAVDGKANAAVIRVLAEHFGVPRSLVELTGGASSRIKRFRIG
What are the official names of this protein?
UPF0235 protein Mvan_2846.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: KATG_FRASN
Sequence: MSENHETVVSELNEESGGGCPVAHERAPHPTQGGGNRGWWPNRLNLKILAKNPAVANPLGEEFDYAAAFRTLDLPAVKRDIAQVLTTSQDWWPADYGHYGPFMIRMAWHSAGTYRISDGRGGGGAGQQRFAPLNSWPDNGNLDKARRLLWPVKKKYGQALSWADLMILAGNVALESMGFTTFGFAGGREDVWEPDEDVYWGPETTWLGDERYTGDRELENPLGAVQMGLIYVNPEGPNGTPDPLAAARDIRETFRRMAMDDEETVALIAGGHTFGKTHGAGDPDNVGPEPEGAPLETQGLGWKNAFGTGKGADAITSGLEGAWTPTPVSWDNSFFETLFGYEWALTKSPAGAYQWKPKGGAGAGTVPDAHDAAKSHAPTMLTTDLALRFDPVYEPISRRFLEHPDELADAFARAWFKLTHRDMGPVARYLGPEVPAETLLWQDPVPAVDHELVDAADVAALKVRVLASGLSVSELVATAWASASTFRGGDKRGGANGARIRLEPQRGWEVNEPDRLAAVLGTLTGIQEEFHAARTDGRRVSLADLIVLAGGAAVEQAAREAGFDVEVPFTPGRTDASQELTDVESFAALEPAADGFRNYLGKGQRLPAEYLLLDRANLLTLSAPELTVLVGGLRVLGANFRQSSLGVLTATPGVLTNDFFANLLDLGTTWRPSGEDDNVFEGRDAATGELTWTGSRVDLVFGSNSELRAFAEVYASDDAREKFVRDFVAAWAKVMNLDRYDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: IAPP_MESAU
Sequence: MHISKLPAALLIFSVALNHLKATPVRSGTNHQMDKRKCNTATCATQRLANFLVHSNNNLGPVLSPTNVGSNTYGKRSAAEIPDGDSLDLFLL
What is the function of this protein?
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
What are the official names of this protein?
Islet amyloid polypeptide, Amylin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU3C_PROMA
Sequence: MFTLPGYDAFLGFLLISAAVPALALVTNKLISPKSQPGERELTYESGMEPIGGAWIQFNIRYYMFALVFVIFDVETVFLYPWAVAFHKLGLLAFIEALIFISILIVALAYAWRKGALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CDIPT_DROME
Sequence: MTIAEHDNVFIFVPNLIGYARIVLALIAFWFMSTNYVISGWCYVTSALLDAVDGQAARAFNQSTRFGAMLDQLTDRCGTTGLLVTLAYFYPRYMFWFQLSIAIDVACHWLFMQTSVVVGRSSHKVNDNFIMRLYYQKDILTFMCCVNELFYVCLYLLHFTYGPLIFGASLFKILAFLTGPFAVLKALISVMHAYVAGIDLAAVDVRERQERRQKSEPVSGKKVE
What is the function of this protein?
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction (PubMed:17151285, PubMed:24828534, PubMed:24603715).  May thus act to reduce an excessive cellular PtdIns content (By similarity).  The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity).  Required for the regeneration of the signaling molecule phosphatidylinositol 4,5-bisphosphate (PtdInsP2) from phosphatidic acid (PA) and maintenance of its steady supply during signaling, thus playing an essential role during phospholipase C-mediated transduction (PubMed:17151285).  This function is essential in photoreceptors for light-activated recycling of PtdInsP2 during phototransduction (PubMed:17151285).  As a key enzyme of the phosphoinositide pathway, indirectly involved in the polarized secretion of basal membrane (BM) proteins in follicle epithelial (FE) cells through promoting PtdInsP2 synthesis in the apical and lateral plasma membranes of FE cells (PubMed:24828534).  PtdInsP2 controls the localization of Crag and perhaps the localization and expression of strat, both of which are essential for restricting the secretion of BM proteins to the basal surface (PubMed:24828534, PubMed:28228250).
What are the official names of this protein?
CDP-diacylglycerol--inositol 3-phosphatidyltransferase, CDIPT, Phosphatidylinositol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Lateral cell membrane; Multi-pass membrane protein. Note=In follicle cells, detected at the apical and lateral regions of the plasma membrane.
Protein: FTHS_THEMA
Sequence: MKPIKEIADQLELKDDILYPYGHYIAKIDHRFLKSLENHEDGKLILVTAVTPTPAGEGKTTTSIGLSMSLNRIGKKSIVTLREPSLGPTLGLKGGATGGGRSRVLPSDEINLHFTGDMHAVASAHNLLAAVLDSHIKHGNELKIDITRVFWKRTMDMNDRALRSIVIGLGGSANGFPREDSFIITAASEVMAILALSENMKDLKERLGKIIVALDADRKIVRISDLGIQGAMAVLLKDAINPNLVQTTEGTPALIHCGPFANIAHGTNSIIATKMAMKLSEYTVTEAGFGADLGAEKFIDFVSRVGGFYPNAAVLVATVRALKYHGGANLKNIHEENLEALKEGFKNLRVHVENLRKFNLPVVVALNRFSTDTEKEIAYVVKECEKLGVRVAVSEVFKKGSEGGVELAKAVAEAAKDVEPAYLYEMNDPVEKKIEILAKEIYRAGRVEFSDTAKNALKFIKKHGFDELPVIVAKTPKSISHDPSLRGAPEGYTFVVSDLFVSAGAGFVVALSGDINLMPGLPKKPNALNMDVDDSGNIVGVS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: SYN_CHLAD
Sequence: MSLLPTATVATIARHVGQRVTLAGWVYHKTEKGKLIFILLRDGSGTIQCVTFKKNVSEATFATAQALTQESSCRITGSVRADERAPGGYELDVEEIELVGPSHEYPITPKEHGVEFLMEHRHLWVRSAKQHAILRIRAEVIAAAQEWLNEQGFVRFDTPILTATAAEGTTNLFATDYFDLGKAYLAQTGQLYVEAGMMSFGKVYCFGPTFRAEKSKTRRHLTEFWMIEPEVAFADHEDNMRLQEQFVSAIVARVLDRRREDLKVLERDISLLEQVVPPFPRITYDQAIELIAAHQGEVEGAYPLPWGEDFGAPHETLIASKFDRPVFVERFPSAVKAFYMQPDPNRPEVALCADLLAPEGYGEIIGGSQRIHDPDLLEQRIRAHGLRLEDYQWYLDLRRYGTVPHSGFGMGIERVVAWITGTRHIRETIPFPRQLYRIYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAG1_RAT
Sequence: MTAKVKDHPPLWGFGTTKTFKIPIEHLDFKYIENCSDVKQLEKILCVLRSGEEGYYPELTEFCEKRLTGLAPRSRALRKDKPAATASSFSAEEWEKIDSDLKSWVSEIKREENTRHFHDPEKHPGVEDPLPPVRGSNSCPRGGKETSSKSKTAKKRIPRDYAEWDKFDVEKECSKIDEDYKEKTVINNKAHLSKIETKIDTAGLTEKEKNFLANREKGKGNEAFYSGDYEEAVMYYTRSLSALPTATAYNNRAQAEIKLQRWSSALEDCEKALELEPGNIKALLRRATTYKHQNKFLEAVDDLRKVLQAEPDNDLAKKTLSEVERELKNSEPASELQTKGKRMVIEEVENSGDEGGKGDEDDHEDDGVDMAAMGNIQKKLMVRSQGGRRSRRARTPMPGAEQQEGQPETGTASTSDNHDLEERRAADSPGDLKSRGNELFRGGQFAEAAVQYSGAIAQLEPTGSENADELSILYSNRAACYLKEGNCRGCIQDCDRALELQPFAVKPLLRRAMAYETLEQYRSAYVDYITVLKIDCRIQLASDSVNRITRILTELDGPKWRERLPPIPAVPASEPLRVWHPAAETPDQDPCPNSCTPTITDEKMFQALKEEGNQLVKDKNYKDAISKYNECLKINSKACAIYTNRALCYLKLGQFEEAKLDCDKALQIDSKNVKASYRLELAQKGLENCRERVADPSQVVLLSPDSSEAARHLDTKNDTAPPSRERERRRIEIQEVDDSSDEEPERPAEASAVEEGWSAERAGKIEVCKPRNAYEFGQVLSTISARKDEEACAQLLVFTAPQDLPVLLSNKLEGDMLLLIMQSLKSHLVAKDPSLVCKHLLYLSKAERFEMMLALTSKDQKEQMAQLFDDLSDAQADCLTAEDIQALRRQYVL
What is the function of this protein?
May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity).  Binds GTP and has GTPase activity (By similarity).  Plays a role in fertilization (PubMed:11517287).
What are the official names of this protein?
Sperm-associated antigen 1, HSD-3.8, Infertility-related sperm protein Spag-1.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle. Note=Colocalizes with tubulin.
Protein: ARGB_SHEB5
Sequence: MSTNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQQVLMVHGGGCLVDEQLAANGMETVKLEGLRVTPPEQMPIIAGALAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDERLGLVGEVTPKDGAYLKFILAQGWMPICSSIAMMDDGQMLNVNADQAATALAKLVGGKLVLLSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWRDASQLIALAKGEAVGTQIQP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_PARL1
Sequence: MSEAEVPEKLDSADINRVLELLPHRYPMLMIDRIIEMKSDESAIGIKNVTNNEPFFQGHFPGHPVMPGVLIVEAMAQTAGALVINHLGTSGSNQLVYFMTVDRARFRKPVVPGDVLHVHVTKIQSRGSVWKYHGEGKVNGQLVAECDLGAMIAGQGTK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMC_SHESM
Sequence: MSTLVQCGYFERGQCQSCRHIKLPMAQQLAAKTQELQQLLAPFVDNAEPQFLPPVVGDSSGFRNKAKMVALGAAHAPVLGIVSPSGEAVSLCDCLLYPADMQALLHRLERFVQQAGIPPYRVDKAKGELKFILLTRSQVRGEYMLRFVLRSRDAIARIERELPALMAEYPQIKVVSVNLQPVHMAILEGEEEIFLTENTRLEERFNDVPLFIRPKSFFQTNPQVAAKLYQTAREWVADFAPASLWDLFCGVGGFGLHCAAKDIPLTGIEIEAEAIACAKMSAQLMGLDKVQFMALDSTDFAKGDAAQTKPELIIVNPPRRGIGESLCHSLSEFAPKAILYSSCNPKTLAKDLGHIRGYRLTKVQLFDLFPHSDHFEVLALLVKD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: IRPL2_HUMAN
Sequence: MKPPFLLALVVCSVVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKRSIKLLSLIKWKGSKSSKLNSKFWKHLVYEMPIKKKEMLPRCHVLDSAEQGLFGELQPIPSIAMTSTSATLVSSQADLPEFHPSDSMQIRHCCRGYKHEIPATTLPVPSLGNHHTYCNLPLTLLNGQLPLNNTLKDTQEFHRNSSLLPLSSKELSFTSDIW
What are the official names of this protein?
X-linked interleukin-1 receptor accessory protein-like 2, IL-1 receptor accessory protein-like 2, IL-1-RAPL-2, IL-1RAPL-2, IL1RAPL-2, IL1RAPL-2-related protein, Interleukin-1 receptor 9, IL-1R-9, IL-1R9, Three immunoglobulin domain-containing IL-1 receptor-related 1, TIGIRR-1.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AMPA_VIBCH
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPVAEQLDKISDGYISSLLRRGDLEGKPGQMLLLHQVPGVLSERVLLVGCGKERELGERQYKEIIQKTINTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVEATKDGLYIFDQFKSVKPEIRRPLRKLVFNVPTRRELNLGERAITHGLAISSGVKACKDLGNMPPNIANPAYLASQARRLADDYESITTKIIGEEEMEKLGMASYLAVGRGSRNESMMSVIEYKGNPDPEAKPIVLVGKGLTFDSGGISLKPGEGMDEMKYDMCGAASVFGTMKAIAKLGLPLNVIGVLAGCENMPGSNAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPECVVDVATLTGACVIALGHHISAVMSNHNPLAHELVNASEQSSDRAWRLPLADEYHEQLKSPFADMANIGGRPGGAITAACFLSKFAKKYNWAHLDIAGTAWKSGAAKGSTGRPVSLLVQFLLNRSGGLDAEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H3_PISOC
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTELRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3, embryonic.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y839_STAAS
Sequence: MLHLHILSWVLAIILFIATYLNISKNQGGSPFFKPLHMILRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHKMFWITMALIIITMVLGVILPLGPISKLFGIG
What are the official names of this protein?
UPF0344 protein SAS0839.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.