PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_RHOPA
Sequence: MARYIFITGGVVSSLGKGLASAALGALLQARGYKVRLRKLDPYLNLDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPATKQDNITTGRIYQDILTKERRGDYLGATIQVVPHVTNAIKEFIVSDNDGYDFVLVEIGGTVGDIEGLPFFEAIRQIKNDLPRGDVIYIHLTLLPYIPSAGELKTKPTQHSVKELRSIGIQPDILLCRTDRPIPKEERRKLGLFCNVRESAVIEARDADSIYAVPEAYHAAGLDDEVLAAFAIAAKEPPQLGRWHEINERIRNPEGAVTIAIVGKYTGMKDAYKSLIEALSHGGIANKVQVKLDWIESEVFENEDPAPFLEHVNGILVPGGFGQRGAEGKIEAARFARERNVPYFGICFGMQMAVIEAARNLAGIEQANSTEFGPTPEPLVGLMTEWVRGNELEKRSQAGDLGGTMRLGAYPATLKRGSRVSQVYGGVTEISERHRHRYEVNTAYKDRLEQHGLKFSGMSPDGVLPEIVEYEDHPWFIGVQFHPELKSRPFDPHPLFASFVQAALVQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TY3H_BOVIN
Sequence: MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARKEREKAEAAASSSESAEAAAWLERDGEAVLTLLFALPPTRPPALTRAIKVFETFEAHLHHLETRPAQPLRAGSPPLECFVRCEVPGPVVPALLSALRRVAEDVRAAGESKVLWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYSTLRGLYPTHACREHLEAFELLERFCGYREDRIPQLEDVSRFLKERTGFQLRPAAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPECCHELLGHVPMLADRTFAQFSQDIGLASLGVSDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQTYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIRHALDGVQDEMQALAHALNAIS
What is the function of this protein?
Catalyzes the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of cathecolamines, dopamine, noradrenaline, and adrenaline.  Uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-Dopa (By similarity).  In addition to tyrosine, is able to catalyze the hydroxylation of phenylalanine and tryptophan with lower specificity (By similarity).  Positively regulates the regression of retinal hyaloid vessels during postnatal development (By similarity).
What are the official names of this protein?
Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Cell projection, axon. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=When phosphorylated at Ser-19 shows a nuclear distribution and when phsphorylated at Ser-31 as well at Ser-40 shows a cytosolic distribution (By similarity). Expressed in dopaminergic axons and axon terminals (By similarity).
Protein: KHSE_PHOPR
Sequence: MSVVVYAPASIGNVSVGFDVLGAAVSPIDGSLLGDRVEVAAGEQPFTLKCVGDFVAKLPVEQEENIVYHCWLVFARELDKKNIELKPVSMTLEKNMPIGSGLGSSACSVVAALDALNRFHNLPLNEVELLALMGEMEAKISGSLHYDNVAPCYLGGLQFMVQELGIISQPVPCFDDWYWVMAYPGIKVPTAEARAILPSQYRRQDVIAHGRYLGGFIHACHSQQPELAAKMVKDVVAEPYRERLLPGFSNARQYALEAGALASGISGSGPTMFSVCNDLEVAKRIARWLEDNYVQNDEGFVHVCRLDSTGSKVTGSEL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PESC_DROAN
Sequence: MRRPKKYESGEATQYISRRAALRKLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSEIRVLYHTKDIRFLLHEQIVWTLRDYKIFAKKSNRDRAIKDFRNLKRRLALFPEIKLDHIVKERYPTFIDALKDLDDCLTLLFLFSTFPSLHLIPREQSNLCRRLTVEFLHYVIASKSLRKVFISIKGYYFQAEIKGQKVTWIVPHYYPFKPQSRQEVDFKVMSIFVEFYTIMLGFTNFRLFHGLNLAYPPQFPTNMLQDNEDTFKDESSFVSDRIAALNFELLRTDKVQEDEEELDIDMELLEQDGDSKRIIKMKQEAQEVARLRTLFKGLKFFINREVPREPLVIIIRSFGGKVSWDSSIFPGSTFDESDETITHQIVDRPSLATQYISRDYIQPQWLFDCVNQRQLLPTNKYFIGEKLPPHLSPFVDSKRDTYIPPEEKALHDPSLIETHEQSDDDSDEEAAQEEEEAVDQELLDAQLQLAYQQETAEYKKYGGPDGVNEDEEDPEEDEEDEDEEEEEELDEQAKRLKEEKQKMSVQSGKVHKVNKRQLHKAEVDEHRLQARMVKPRHRNLFRKLIREKQTKEKEEWLLRKKRRTFEAGEKEARKTAKRAARKEAAAAAAKASKLGK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: LEF10_NPVOP
Sequence: MTHVLSAAANDLIACVLRDNLFSADGECLRYVVCKEAGHVESVYIGEIGAAQAHSGDQNAVLDASSASDVSSSASSRRVS
What is the function of this protein?
Involved in late/very late gene activation.
What are the official names of this protein?
Late expression factor 10.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-10 family.
Protein: ADH3_YEAST
Sequence: MLRTSTLFTRRVQPSLFSRNILRLQSTAAIPKTQKGVIFYENKGKLHYKDIPVPEPKPNEILINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGHEGAGVVVKLGSNVKGWKVGDLAGIKWLNGSCMTCEFCESGHESNCPDADLSGYTHDGSFQQFATADAIQAAKIQQGTDLAEVAPILCAGVTVYKALKEADLKAGDWVAISGAAGGLGSLAVQYATAMGYRVLGIDAGEEKEKLFKKLGGEVFIDFTKTKNMVSDIQEATKGGPHGVINVSVSEAAISLSTEYVRPCGTVVLVGLPANAYVKSEVFSHVVKSINIKGSYVGNRADTREALDFFSRGLIKSPIKIVGLSELPKVYDLMEKGKILGRYVVDTSK
What are the official names of this protein?
Alcohol dehydrogenase 3, mitochondrial, Alcohol dehydrogenase III, YADH-3.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RK3_PORPU
Sequence: MSVGILGTKVGMTQFFDETGLSIPVTVIQVGPCVITQIKSMSTDGYNAIQVGYKQVVEQKLSKPLLGHLKKSQSPPLKYLREYLVESIEDFEVSQVFSTNIFEVGQKVNVSSKSIGKGFSGYQKRHHFSRGPMSHGSKNHRQPGSIGAGTTPGRVYPGKNMAGQMGNKKVTIKNLQIVSINIENDLLLLKGAVPGKQGALVKVSK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VE4_HPV6A
Sequence: MADDSALHKKYPFLNLLHTPPHRPPPLCPQAPRKTQCKRRLENEHEESNSHLATPCVWPTLDPWTVETTTSSLTITTSTKEGTTVTVQLRL
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RS11_IGNH4
Sequence: MPKEIRWGVAHIFSSPNNTFVHITDITGSETASRVTGGMVVKADHEKPSPYAAMIAAARAAQQAMERGITAIHIKVRAPGGYGPKTPGPGAQAAIRALARSGFIIGRIEDVTPLPHDTIRRPGGRRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PPA6_PONAB
Sequence: MITGVFSMRLWTPVGVLTSLAYCLHQRRVALAELQEADGRRPVDRSLLKSKMVQVVFRHGARSPRKPLPLEEQVEWNPQLLEVPPQTQFDYTVTNLAGGPKPYSPYDAQYCETTLKGGMFAGQLTKVGMQQMFALGERLRKNYVEDIPFLSPTFSPQEVFIRSTNIFRNLESTRCLLAGLFQCQKEGPIIIHTDEADSEVLYPNYQSCWSLRQRTRGRRQTASLQPGISEDLKKVKDRMGIDSSDKVDFFILLDNMAAEQAHNLPSCPMLKRFAQMIEQRAVDTSLYILPKEDRESLQMAVGPLLHILESNLLKAMDSATAPDKIRKLYLYAAHDVTLIPLLMTLGIFDHKWPPFAVDLTMELYQHLESKEWFVQLYYHGKEQVPRGCPDGLCPLDMFLNAMSVYTLSPEKYHALCSQTQVMEVGNGE
What is the function of this protein?
Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol.  Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid.
What are the official names of this protein?
Lysophosphatidic acid phosphatase type 6, Acid phosphatase 6, lysophosphatidic.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSBC_MARPO
Sequence: MKILYSQRRFYPVETLFNGTLALGGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEIVDTFPYFVSGVLHLISSAVLGFGGIYHALIGPETLEESFPFFGYVWKDKNKMTTILGIHLILLGAGAFLLVFKALYFGGIYDTWAPGGGDVRKITNLTLSPGVIFGYLLKSPFGGEGWIVSVDNLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLGAIAVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYIMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLSKLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: GLNE_BURMA
Sequence: MTDASDLLSLSYSHYLARAAAARPALAERIAAWAAAPVTRAALDARLDELLAQGGQPPSEDALKKALRQLRGEAFGAVAERDLAGRADVAEVTGTMTDLAEAAIQRALALLAAELEAQYGEPRGPSGERLALGVVGMGKLGGRELNVSSDIDLIFVYEDDGETAGGARAPISVHEFFTRLGRRLIGVLSEATADGYVFRVDMRLRPNGDSGPLVCSLGMLEEYFYVQGREWERYAWIKGRLVTERASAAARRLAQQLDAIVKPFVYRRYLDFGVIGAIRSLHEQIRQEARRRATMRPDKADDIKLGRGGIREIEFSAQVFQLIRGGQDAGFRVQPTLAVLRHASASGLITEEVRAGLTHAYLFLRTLEHRLQYRNDAQTHAMPVDPAERAALAASLGFADYAALIDRLDQHRAFVEAQFDQVFADKADGGARREDDQAAGCIWSGALADDGADEALVARLAELGFADPAAVLARLQAVWRSSRYAGLPESSRVRFDRVAHRALEAAPGIDAAHRDETVVRCFDLLETVGRRGAYLALLTEYPAALRRVLSVLGATRWGGGYLIRHPQLLDELLDDEAIDSPFDWPAFKDALRRRLAAADGAEHQMDLLRHAHQAEVFRILLLDLAGRLSVEHVSDRLSELADAMLDVTIEVVWSQLAKRHRDTPCFAAIAYGKLGGKELGYASDLDLIFLYDDPDERAADVYTTFARRLITWLTTATGAGTLFDIDLRLRPNGEAGLLVTDLDAFRRYQLREGDAANTAWVWEHQALTRARYSAGDARIGAAFEAIRVQVLTTPRDAAVLAKEIVEMREKVLAGHPNTTERFDLKHDRGGMVDIEFAVQYWVLLHAARHPEMIRNTGNIALLREVSRFGLMSEEEAETVGAAYRTYRKLQHRLRLDGMEKARVEPERVAAERQAVAALWARVFGA
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: BIOF_YERPP
Sequence: MSWQDKIAQGLQRRRDAAAYRTRQVNEGANGRWLQSGERQYLNFSSNDYLGLSQNDEVIAAWQQGARRYGVGSGGSGHVTGYSQPHARLEQQLADWLGYPRALLFISGYAANQAVLTALTDADDRILADKLSHASLLEAAAHSPAQLRRFQHNQPEALQNLLIKPCQGQTLVVTEGVFSMDGDSAPLAALQQQTSAAGGWLLVDDAHGIGVHGEGGRGSCWLQGVQPELLVVTFGKAFGLSGAAVLCQEPVAEYLLQYARHLIYSTAMPPAQACALQAALRQVQQGDALRQQLQQRIRQFRTAAAHLPLQLGASKTAIQPLLVGDNQQSLIWAEQLRAAGLWVTAIRPPTVPPGSARLRITLSAAHQPEDIDRLLEVLYGLCH
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: IRAM_ECODH
Sequence: MKWIVIDTVIQPTCGISFSAIWGNMKMIIWYQSTIFLPPGSIFTPVKSGIILKDKEYPITIYHIAPFNKDLWSLLKSSQECPPGESKITNKCLHNSCIIKICPYGLK
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation.
What are the official names of this protein?
Anti-adapter protein IraM.
What is the protein family that this protein belongs to?
Belongs to the IraM/RssC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG30_KOMPG
Sequence: MFSRKQVQKRNNELSSLHCSNSSNSLNRIHKNEETAKGTVGVNARGNNRSDNVASPGQLRPRTSSILTDNSEWILFSPENAEGEYVITSSDGIRRTNSNHYYYNYNEDDILSSSRRSSEDVYDAEQEYTEQPVNNHVQVEDEEDDDSIINDLTHVVDDYDYEEEDDKQDLTTRIDNWRKKQVSELLNELNHDDDLDPVLNRDKIDLIQSWGIENEKLNTKPRAKKRQRKSKRASFYGQDLLSKYSMEDLKIIKQIVAQLRDDLDKVKHDKPSSPLPNYHNTLKQAPSSNSQNPSFISYYSNYLTKNNSQQTPNSQSTSGSLLNNPNLEKYLPLFLKNLLYEDSNGSHQHPETSEKEHFWDNDLKSVNSSILTLSSNSKLKQEIL
What is the function of this protein?
Acts as the peroxisome receptor for pexophagy.  Required for both micropexophagy and macropexophagy, but not for the cytoplasm to vacuole transport (Cvt) or autophagy pathways.  Required for functional micropexophagic apparatus (MIPA) and relocation of ATG11 to the peroxisome-sequestering arms of the vacuole.
What are the official names of this protein?
Autophagy-related protein 30.
What are the subcellular locations of this protein?
Vacuole lumen. Preautophagosomal structure. Peroxisome membrane; Peripheral membrane protein. Note=Surrounds the peroxisome cluster, but a small amount is also inside the vacuole in methanol-grown cells. Upon induction of micropexophagy, localizes inside the vacuolar lumen. Also localizes near peroxisomes during early stages of micropexophagy.
Protein: ISPH_HAEI8
Sequence: MKIILANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVNGLRDRGAIFVEELSEVPDGAIVIFSAHGVSQAVRQEAKDRNLKVFDATCPLVTKVHMQVARASRKGTKAILIGHKGHPEVEGTMGQYSNEDGGIFLIEKVEDIARLPMQDNDDLTFMTQTTLSLDDTAETIAALKEKYPAIQGPHKNDICYATTNRQEAVRELAKLSDLVLVVGSKNSSNSNRLAELASRMGIKSQLLDDPSDIQDDWFNDVKTIGITAGASAPEELVQSIISRLKEFGADTIEELQGLEENMFFEVPKELRIKEVN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: CP2D1_RAT
Sequence: MELLNGTGLWSMAIFTVIFILLVDLMHRRHRWTSRYPPGPVPWPVLGNLLQVDLSNMPYSLYKLQHRYGDVFSLQKGWKPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVILASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKEAGHLCDAFTAQAGQSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMVKLVEESLTEVSGFIPEVLNTFPALLRIPGLADKVFQGQKTFMALLDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRFTSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPHRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPVGQPRPSTHGFFAFPVAPLPYQLCAVVREQGL
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2D1, CYPIID1, Cytochrome P450-CMF1A, Cytochrome P450-DB1, Cytochrome P450-UT-7, Debrisoquine 4-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: CCL13_HUMAN
Sequence: MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT
What is the function of this protein?
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils.  Signals through CCR2B and CCR3 receptors.  Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation.  May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.  May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
What are the official names of this protein?
C-C motif chemokine 13, CK-beta-10, Monocyte chemoattractant protein 4, Monocyte chemotactic protein 4, MCP-4, NCC-1, Small-inducible cytokine A13.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCD_SALPB
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RPSE_CLOAB
Sequence: MKFLLRLLSKLLCRIKLFSNRLYYIGGNDALPPPLSKDEEDDLVNKLVNGDESIRSILIERNLRLVVYIARKFENTGVGVEDLISVGTIGLIKAVNTFDPTKKIKLATYGSRCIENEILMYLRRNSKVKAEISFYEPLNIDWDGNKLLLSDILGTDNDCVYNLIEGEVDKQLLLFALKKLNEREKRIVELRYGLTGVGEKTQKEVADMLGISQSYISRLEKRIIKRLKKEINKML
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is responsible for the expression of sporulation specific genes (By similarity).
What are the official names of this protein?
RNA polymerase sigma-E factor, Stage II sporulation protein GB.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: H2AZ_CHAGB
Sequence: MAGGKGKSSGGKSSGGKTSGVDGTKKQQSHSARAGLQFPCGRVKRFLKQNTQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPHINRALLLKVEQKKKAKAIEA
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received.  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins.  Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: POL2_BAMMN
Sequence: MMMNSTIRQGWQQVLKRFSIPASGDRLIISNPTDQPIGLFGAFDTSLQTLSQVGDDPEVLKQKIHIPTHLDIASALEASPRSFPWIFLTNSFCTFGGSIHAQNLQAFATAEFKSGFCYMNLLVPLSFDIIDAHADSFRVFVEQLPDMLGAYPSLSMVLNVMLHAATRFPEIVSSPVPTIAFDAESLQFHVTDKRGVPGMWNILKAGRVYELLSLAADGVGCEYMLYPVGAAPQYSFWKKSMDHFTSDRFVEFLAMQNLLASALEQDYTTHDALDALLAALQNAGYTNVVARERRFPNGHDPSTVWLNLSEAPISEKLTDLKRYLLVGHRSDDTADITHNVHQYVFEVLKTMSVQFSKRTNAYNRARFEVNHKVIWNAEYGRGPQQNAELEALVLFLNRQSLEIENILHRTTSPVVVTNWQPDVPTAAPEVSEGEPTHAVATPMTEAPAHATPVEVVNLPSTRSYWAETLVGVLTAVLGTIFALLTRALIRAKRLRRKPTFPWVTLDSGDEDDDHSGGGGGGPQTPGGQPPASPAHRTHQSRLSVQDIASDTSLLSVDLDEDTLSQYDETFQRIRRALFETSFTDILQNSARWISALEAMALADGNAPYTLLAQYLNGIEEAYTSFRNTGHVSRATLSSFFALEDSLRAAGIAFGATTPTQTIQNQFADSPARRWKTRFEQIACELGDASIKSLADLADIIDTERERSDLTQFDVLAASSISSLCRAVRIISDTTDPDAQLALVENATAMQNNINAILGTNVSIPFLSATRRLLVTRRIQQAGAENRSGATPETIQQLADAELIVSEANMFNEMATSQRDIANATQEATIREHVLSPVNALANVGMAAAFFRSGGMRSRALHPAMPTMPGVSAATGRPIFQAFRGRGHRLNR
What are the official names of this protein?
Genome polyprotein 2.
What is the protein family that this protein belongs to?
Belongs to the bymoviruses polyprotein 2 family.
Protein: PM47B_CANBO
Sequence: MSSREYDDLSHAFAGAGGGLLSMTLTYPLVTLTTHAQTMVRLKKNEEEEKENSNEDGSLSPKSSNTSNISQKKISQFEILKKILKDQGAKGLYNGLESALFGIAVTNFVYYYFYELTGKTLSRRSNPQTTSGSKKVTLKKGLSVWQSMAAGAVAGTISRVATNPIWVANTRMTILSKNQGKLGKLNTIEAIIYILKNEGWQKLFTGIVPALFLVLNPIIQYTIFEQLKSFIVKIKKRNVTPVDALLLGAFGKLIATIITYPYITLRSRMHVKSMTENNEDSEKERTDSVQSLPEDGSDEDNSKENPYAETINKIISKLPSPIVSMFIIGYKMYKEEGVSSFYRGLSVKLLQSILNAAFLFYFKEELLILSDAIIKSTKRVTGLANNPYNAKDVIHSFEKALCMRNPRSRTTTVPQTNEE
What is the function of this protein?
May have transport activity.
What are the official names of this protein?
Peroxisomal membrane protein PMP47B.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: KN14G_ARATH
Sequence: MATTSEINNDLSFSVVSIVEDVLQQHSSRSSDVGLVSRKVEESSLRRYEAAGWLRDMIGVSNGKDFPGEPSEEEFRLGLRSGIVLCNVLNKVNPGSVSKVVEAPDDVADGAALSAFQYFENIRNFLVAIEEMGLPSFEASDMEKGGKSIRIVNCILALKSYSEWKLKGENGPWRYGSNMKHNFGSRKLFLRKSSEPFVSSISRTQSTDMLSTDQPLSSDGDSRSINGLVRSFIADRKHEDIPNVVESVLNKVMEEVQQRLSIHNEMMKSSSKPIPEDDSSCETVVRSQLCDARQHEEAEENSPPQVVEKKFQRTNFEHHEEQKILLNQQKHIQELKQTLYTTKAGMKLLQMKYQEDFFHLGKHLNGLAYAATGYKRVLEENRKLYNLVQDLKGNIRVYCRVRPFLPGQESGGLSAVEDIDEGTITIRVPSKYGKAGQKPFMFNKVFGPSATQEEVFSDMQPLVRSVLDGYNVCIFAYGQTGSGKTFTMTGPKELTEESLGVNYRALADLFLLSNQRKDTTSYEISVQMLEIYNEQVRDLLAQDGQTKRLEIRNNSHNGINVPEASLVPVSSTDDVIQLMDLGHMNRAVSSTAMNDRSSRSHSCVTVHVQGRDLTSGSILHGSMHLVDLAGSERVDKSEVTGDRLKEAQHINKSLSALGDVISSLSQKTSHVPYRNSKLTQLLQDSLGGSAKTLMFVHISPEPDTLGETISTLKFAERVGSVELGAARVNKDNSEVKELKEQIANLKMALVRKGNGNDVQPTAIPINRERISRRRSLETPTIRPKLPTMGNTSNNSRPQIMDLSGPEAFNDSTASSRRHSLDIHELMKSSSPAWPRQPLNGKDEDRESKSGEWIDKHEELIQNQNPNSPEQFYQSMVPQQQSLYGGKQDFEVQSITDNESDEAATSDCSDSDLLWRLSVQVNVPKVSNIQNSANPKPKKIQPRTAKLSETRSLIPSLIPAPSKRPPNTVNSQPQRPTRDGKRRLSLGT
What is the function of this protein?
Microtubule-binding motor protein.
What are the official names of this protein?
Kinesin-like protein KIN-14G, Kinesin-like protein KatD.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.