PharMolix/UniProtQA huggingface dataset:
Protein: HEM6_ECOL6
Sequence: MKPDAHQVKQFLLNLQDTICQQLSAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_CHLP8
Sequence: MRTGIFGGSFDPPHNGHLAMCLFARELLRLDRLIVSVSRNPFKTGAHASDDDRVSMARLLTDEVNAAGRFAESSSWELETDGPSYTVDLLRHIADLYPDDELLLLVGEDSYRQMGQWKAASEIPRLCQIVYFGREGYENCQHDAEALHLPVRRIDFDMPVSATEIRRLVAAGQPVSQLVPPSINHYIAEHGLYRS
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: IDI_SHIBS
Sequence: MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDFRYRATDPNGIVENEVCPVFAARTNSALQINDDEVMDYQWCDLADVLHGIDATPWAFSPWMVMQAANSEARKLLSAFAQHN
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDB1_HUMAN
Sequence: MSVGCACPGCSSKSFKLYSPKEPPNGNAFPPFHPGTMLDRDVGPTPMYPPTYLEPGIGRHTPYGNQTDYRIFELNKRLQNWTEECDNLWWDAFTTEFFEDDAMLTITFCLEDGPKRYTIGRTLIPRYFRSIFEGGATELYYVLKHPKEAFHSNFVSLDCDQGSMVTQHGKPMFTQVCVEGRLYLEFMFDDMMRIKTWHFSIRQHRELIPRSILAMHAQDPQMLDQLSKNITRCGLSNSTLNYLRLCVILEPMQELMSRHKTYSLSPRDCLKTCLFQKWQRMVAPPAEPTRQQPSKRRKRKMSGGSTMSSGGGNTNNSNSKKKSPASTFALSSQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQFDAANGIDDEDSFNNSPALGANSPWNSKPPSSQESKSENPTSQASQ
What is the function of this protein?
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors.  May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions.  Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1.  Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression.  Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.
What are the official names of this protein?
LIM domain-binding protein 1, LDB-1, Carboxyl-terminal LIM domain-binding protein 2, CLIM-2, LIM domain-binding factor CLIM2, hLdb1, Nuclear LIM interactor.
What is the protein family that this protein belongs to?
Belongs to the LDB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURA_KORVE
Sequence: MVSKGKTAVVIGAQWGDEGKGKIVDVLSENFRVVARYAGGHNAGHTVLIGGKKFVLQLIPCGVLRPGCRGVIGNGVVLDPIAFLNEVQRLRDLGVAVDGNLFVSSRAHVILPYHRMVELASENAPGRVKIGTTSRGIGPSYEDKMGRRGLRVADLLDSTLLKKHIENACKEKNTIVHALFNAEPIDPDKMYNEYAKAAEKVAPFVTDTAVLLNNAINSGESVMFEGAQGTMLDIDHGTYPFVTSSSATSGGAVIGTGVPPTSISTVIGVTKAYCTRVGEGPFPSELHDAMGDAIRKKGNEFGAVTGRPRRTGWLDLPLLRYSNMINGTEWLVVTKLDVLDELDEIPVATSYKIDGKESEEIPAQGCGFDKIEPIYTKLPGWKTDTTKISKYEDLPAKTKEYLKFVEQQSGAKVGILSTGPDRDQSIYTDAFVNALGLKHLGK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XNI_YERPN
Sequence: MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRHQCLPDYKAGRSPMPDNLQQEMPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQVTIVSTDKGYCQLLAPNIQIRDYFQKRWLDMPFVKQEFGVLPRQLPDYWGLAGISSSKIPGVAGVGAKTATLLLQQADTLEVLYQNLESIPEKWRKKLQQHQQMAFTCKQIATLKTDLLLSGNLQQLRLKK
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: SLYX_SHEB9
Sequence: MQGVQAQIEDLETKLAFQELTVEELNQEVIKLNRLVAHQQHQIHMLIGKLQDMEPSNMATQAEETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: COXE_DICDI
Sequence: MSHALPALIKMHITKDIGYGLLLGIIPGVWFKYQIGQSIQKREDFYAAYDKRN
What is the function of this protein?
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
What are the official names of this protein?
Cytochrome c oxidase subunit 7e, Cytochrome c oxidase polypeptide VIIe.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: RL1_BRUSU
Sequence: MAKISKRINKIREGVDRNKLYDLSAAIGLVKERAVAKFDETVEIAMNLGVDPRHADQMVRGVVNLPNGTGRTVRVAVFARGDKAEEAKKAGADIVGAEELFEIVNGGKIEFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTTDVAAAVAASKGGAVEFRVEKAGIIHAGIGKVSFDNAKLEENIKAFADAVIKAKPSAAKGEYVKRVSISSTMGVGVKVDPSTVKVVD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PYRG_ESCF3
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: HSPQ_SALAR
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPEYSLDEPSPDELAVNDELRAAPWYHVVMEDDNGQPVHTYLAEAQLRSEMRDEHPEQPSMDELARTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_NITEU
Sequence: MDENKNKALSAALAQIEKQYGKGSIMRLGDSDVAKDIQVVSTGSLGLDIALGVGGLPRGRIIEIYGPESSGKTTLTLQAIAEMQKLGGTAAFIDAEHALDPQYAQKIGVNVQELLISQPDNGEQALEITDMLVRSGSVDVVVVDSVAALTPRAEIEGEMGEPQMGLQARLMSQALRKLTANIKRTNTMVIFINQIRMKIGVIFGNPETTTGGNALKFYASVRLDIRRTGSIKRGEEMVGNETRVKIVKNKVAPPFKQADFDILYGEGISRESEIIELGVLHKLIEKAGAWYSYNGEKIGQGKDNVRDYLKEHKSIAHEIEQKIRAAVGLAETDSRVVPPSSGE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGA31_CANAL
Sequence: MKFLTAASLLTLSSSALAAIKDIQLYAQSSNNEVNDFGISSRHEGAALNYLFLAAPGVAENLKYDDETKTVYTELKAGSSTVRQPLNVGNTVLQLGGSGDGTKVDIAEDGTLSFDGSDSVGAAKNINDPYNYSKDSYAVVKGGDGAIPIKLVAKFTGDDKESASSSSSSAAPEPTASSSEAPKETPVYSNSTVTLYTTYCPLSTTITLTVCSDVCTPTVIETSGSVTVSSVQVPSKTASSEAAPPKTTVDSVSKPAPSGKKPTAAVTSFEGAANALTGGSVAIAVAAAIGLVF
What is the function of this protein?
Component of the cell wall involved in virulence which plays a role in the relationship between C. albicans and the host (By similarity).  Involved in the regulation or assembly of chitin within the cell wall.
What are the official names of this protein?
Cell wall protein PGA31, GPI-anchored protein 31, LDG family protein 5.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI- anchor.
Protein: MNME_CAMFF
Sequence: MNIVALASAYGVGSISIVRLSGDGAYDLAINLCKKPLTPRYAHLRKLYCENMVFLDEAIVIYYKAPFSFTGEDVVEFQTHGGVVVANLIIDELLRLGARVANPGEFSKRAFLNGKMDLVKAESIQSLINARSEGAAKILARTMNGELSVFVNSLRDELIKILAYTETCIDYADDDLPSDILHSSKDLLLNSYKKLEHIINISNSKKGLIDGYKVAIIGRPNVGKSSILNSLLHYERAITSETAGTTRDTIEEQIKFGSHLVRIIDTAGIRDEFDSSIEAAGIEYSKRAAREADIIFCVFDSSQKASLEDRQILEFISNLNKKTIYVLNKSDLEFKFDISLNAVLVSAKLDSTPLSKELESYLNSQDTNDIMLSSNRQIEASRLASEAIKNALELLNESELELFAYELNIALKHIGSITKPMENSELLDKMFSSFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_ECOHS
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PIMT_PROMH
Sequence: MLSRSMKDLLTMLKQHGINDERLLEAMSKVPRELFIDEALSHKAYENTALPIGNGQTISQPYIVAKMTSLLELQATDSVLEIGTGSGYQTAVLANLVHHVSSVERIKILQWQAKRRFKHLDLHNISTRHGDGWEGWVSKGPFNAIIVTACATEVPQRLLMQLADGGRMIIPVGEQQQMLKFIRRLGNDFHYQSIEAVRFVPLIAGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOA1_MIRAN
Sequence: MKAVVLTLAVLFLTGSQARHFWQQDEPQSPWDRVKDLATVYVDVVKDGGRDYVAQFEASALGKQLNLKLLDNWDSLSSTVAKLREQIGPVTQEFWDNLEKETEVLRQEMSKDLEEVKKKVQPYLDEFQSKWHEEVELYRQKVAPLGAELREGARQKLQELQEKLSPLAEELRDRARAHVDALRAQLAPYSEQLRERLAARLQALKEGGGAALTEYHAKASEHLSALREKAKPALEDLRQGLLPVLENFRVSLLAAVDEATKKLNSQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility (By similarity).
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_LEPBL
Sequence: MSHNSQIQKIQAREIIDSRGNPTVEVDVTLMDGSFGRAAVPSGASTGEYEAVELRDGDKQRYLGKGVLKAVEHVNVKIQEILKGQDALDQNRVDQLMLDADGTKNKGKLGANAILGTSLAVAKAAAFHSKLPLYRYIGGNFARELPVPMMNIINGGAHADNNVDFQEFMILPVGAKNFREGLRMGAEVFHSLKSVLKGKKLNTAVGDEGGFAPDLTSNVEAIEVILQAIEKAGYKPEKDVLLGLDAASSEFYDKSKKKYVLGAENNKEFSSAELVDYYANLVSKYPIITIEDGLDENDWEGWKLLSEKLGKKIQLVGDDLFVTNIEKLSKGITSGVGNSILIKVNQIGSLSETLASIEMAKKAKYTNVVSHRSGETEDVTISHIAVATNAGQIKTGSLSRTDRIAKYNELLRIEEELGKSAVYKGKETFYNL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TSAD_RICTY
Sequence: MKKILGIESSCDDTAISIITESRKILSNIIIPQNTEHAVFGGVVPEIAARSHLSNLDQALENVLTKSNTELTEISAIAATSGPGLIGGVIVGSMFARSLSSALNKPFIAINHLEGHALTVRLTDNISYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAIGETFDKVAKMLNLSFPGGPEIEKRAKLGNPHKYKFPKPIINSGNCNMSFSGLKTAVRNLIMSLKEVNDSVINDIAASFQFTIGAILSSKMLNAIRLYQQILNYYYENVDYTTNLNLKSFRQDEFNLNHLQDITRPKSRIYLQNSFRSNLLNDTIVIAGGVAANKYLQEILSNCTQTYGYRLIAPPMHLCTDNAAMIAYAGLERYNNKLFSPLNFCPKAKWSLEDI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_LIMRJ
Sequence: MVQRQINWSLIDRVRAKNPIVLNLANLVTIDKVADAVSAVGASPIMSVEPAEADEMVMLANALSINLGTINEHQATQIRTVLRAATPLKPLVLDPVAVSAVPSRLKFAHSLLNDFHFDVIRGNASEIAALVEADNTSHGIDAGKVPNQVQIAETCARRYHSIVVLTGETDIITDGQVVYENPFSAEMLTMNVGSGDMLSSIIAAFLGITTNTWDACIVATVLVSAAGVLANRYSVGLGSWQVQFFDQLSIMDTKALLEFFDESEEDYLD
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: IFT80_MOUSE
Sequence: MRLKISLSKEPKHQELVSCVGWTTAEELYSCSDDHQIVKWNLLTSETSLIVKLPDDIYPIDLHWFPKSLGIKKQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGSQPHEHPITSVAWAPDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSIDGTQIAGACGNGHVVFAHVVEQRWEWKNFQVTLTKRRTMQVRNVLNDAVDLLEFRDRVIKASLNHAHLVVSTSLQCYVFSTKNWNTPLIFDLKEGTVSLILQAERHFLLVDGGGIYLHSYEGRFISSPKFPGMRTDILNAQTVSLSNDTIAIKDKADEKIIFLFEASTGKPLGDGKLLSHKNEISEIALDQKGLTNDRKIAFIDKNRDLYITSVKRFGKEEQIIKLGTMVHTLAWCDTCNILCGIQDTRFTVWYYPNTIYVDRDILPKTLYERDASEYSKNPHIVSFVGNQVTIRRADGSLVHISISPYPAILHEYVSSSKWEEAVRLCRFVKEQSMWACLAAMAVANRDMVTAEIAYAAVGEIDKVRYINAIKDLPSRESKMAHILMFSGNIQEAETVLLQAGLVYQAIQININLYNWERALELAVKYKTHVDTVLAYRQKFLDTFGKQETNKRYLQYAEGLQIDWEKIKAKIEMEITKERDRSSSGQSSKSVGLKH
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
What are the official names of this protein?
Intraflagellar transport protein 80 homolog, WD repeat-containing protein 56.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Note=Basal body and ciliary axoneme in the chondrocytic ATDC-5 cell line.
Protein: FLIW1_HELPH
Sequence: MNYFLKAPILGFEHINEVRLEKIDSLFSRLMGQTNSPMALDMVLVNPYCLREYSFVIPKYIELLLELDSHSKVEVYCVVVLQKNLEDSMVNFLAPLVFNSKNGFGAQVALSMMDYPDFGFRDPLKSFVVKERERA
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW 1.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL24L_GLASK
Sequence: MTAQKSKYFNRIMTMNTLLFSLLTVGFSQAYADVVLEKQVKITDDGLHFDGKDLNHGNIDSADPGEKYDFFFGPNISAHGDAVKTYKHYVFMTWYKGGKSERNVMLSRYNTQTQTIATIEFPHRHTGFRGNPLIGESHNTIGLAVSPNNGTIHMVYDLHAYDDNNHDGKFKDDFFRYSFSVENAADLPDDQFTLDKFVKDTSSISQGPDDYKHISMTGDIADKSNFARLTYPKFFTTTDGTLLLYMRLGGNNNGAYVFNRYDEETQTWSKFTKFNENNQKNFGNPYNWGLYGNMKYVNGKLRVGFQQRSSDNNDRYQYQNGVYYAYSDHPEGFGDWKNHKDDEITYPLVNSDEIKVLEPGDYISHQEANSVYIVGSFDWTVTKKGDVHFISKVRSTNRSRPDYEEEYLHSYKPAGADEFITTTDFTGASQIYTAGDNIYIVGLKNGRPYVERAKGGTNDFVRVYEATSGPVFDHGTLYIKDGKVYYYLMEKTSGNAMPLYLQIIDLDLESEANAPQVAFPSTSLTVEQGYEQLSLGIDATSSIEGRTIESVTLYLNDELVRTDTTVPYLFGHASKPHETGAMGWKDEHEPNPNPLGPGEHIFKAVAVDSEGDTGLATMRLTVQSNAPMVSFPTQLIEVDEGYEKLSVSVDASSSVEGRTIESVTLFINGEEVRTDTTIPYLWGHGSKPHETGAMGWREDHAPNPNPFLAGEYVFTAIATDSQGEQSETSMTLIVNGEATPPIVTWPNEVVTVTEGYKRLGITIEAEASSENATIESVTLYRNDELVRVDTKYKWNFGHSFAPYEFGAMGWLETHEPNPSPLLAGTHTFKVVAKDSTGLEGEAFMTLIVLPPAGPSISFDEPDIELMTGYESLSVSTYVATVNESVDIISVALFIDDVLVRENLEAPYVWGDANHPNELLSLEVGSYEFKAIARDTNDQVSEVSLLVSITLFGDFDGDNDVDRTDVRAFSSAIRSGEALDQRYDFNEDGVVDRSDTRGLTKICSRPRCAS
What is the function of this protein?
Ulvan lyase involved in ulvan degradation (PubMed:28684315).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl).  Ulvan lyase catalyzes preferentially the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acid GlcA, but not IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end.  The most abundant end products in the degradation of the ulvan polysaccharide were deltaUA-Rha3S disaccharides and deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides (By similarity).
What are the official names of this protein?
Ulvan lyase, long isoform, Ulvan lyase A.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 24 family.
Protein: MTLD_NEUCR
Sequence: MAANNYTKKAVHFGAGNIGRGFVACFLHNSGYEVIFADVNADLINALNASPSYKVIEVGSEGTEESTITNYRAINSRTNEEELIQEIATAEVVTCSVGPNILKFIAPVIAKGIDRRSEDLPPVAVIACENAIGATDTLAEYIKDPKNTPSHRLENYEKRARFANSAIDRIVPAQDADAGLDVKLEKFYEWVVDRTPFKDMSPPDIKGINWVDNLLPYIERKLYTVNTGHATAAYHGYIRRKSTVYDALQDKDIQEEVKKALENTSHLITQKHGIDEQAQHEYVEKIVRRISNPHLEDAVERVGRAPLRKLSRKERFIGPAAELAEHGKDCSALLDAAEMAFRFQNVEGDEESAELAKIMASNKPEDVVKQVCGLNEQEKLFPKVVEVVQRVQADLHDD
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase, M1PDH, MPD, MPDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: AKTP1_DROWI
Sequence: MTLDLDASKKDDKLLLTTVQQEYKILAEYKMIESEKIGGVYVIPSYANSLQWFGVFFGRKDFYSEGVFRFTLLLPDRFPDDKTLPSIIFQQKIFHPLICPYTHSLDISHAFPEWRCGDDHLWQLLKYMQAVFSDPLESIRHVEMDKLKNSEAADLLINNREEFANRTRENIRESLAHIYDTPITEDPHYITFEKFQSEVHGPVLEGIKAGQSKHLESQSQQSNNGGNGGGGGAATGLSWVKEGEFKPLSVE
What are the official names of this protein?
Protein crossbronx.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: Y2282_SHEDO
Sequence: MELTEFEARVIGCLLEKEVTTPDQYPLSLNALTLACNQKSSREPVMSLTESQVQASLDELAKKRLVSEQSGFGSRVVKYKHRFCNTEFSELQFSSAELSLICLLLLRGPQTPGELKSRSQRLHEFSHVSEVEHCLYSLSQSDKPHVAMLAREPNKREHRYIELFSHGVSEALTLAADTQHQRPPQTPHLSSRTNVDNSYESDERFTQLEGRINQLEQQVASLEAKLLGLLSNT
What are the official names of this protein?
UPF0502 protein Sden_2282.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: DEF2_RAT
Sequence: MRTLTLLTALLLLALHTQAKSPQGTAEEAPDQEQLVMEDQDISISFGGDKGTALQDADVKAGVTCYCRSTRCGFRERLSGACGYRGRIYRLCCR
What is the function of this protein?
Active in vitro against S. aureus, fungi, Gram-positive and Gram-negative bacteria and to a lesser extent against an enveloped virus.
What are the official names of this protein?
Neutrophil antibiotic peptide NP-2, RatNP-2, Neutrophil defensin 2.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCNI2_HUMAN
Sequence: MASGAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDLDERRLLCHLQLAQDREARLWRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKKAQVGDMQYSCCKELVMQQLRSLQSSSCTDNFVSPAN
What are the official names of this protein?
Cyclin-I2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
Protein: TPM_SCHHA
Sequence: MDGIKKKMIAMKLEKENAMERAVQYEELLKKKEEEREKRESEIAELNTKMKQAQIDCDEVQETLQEQMNKLEETDKRATNAEAEVAAMTRRIRLLEEDLEVSSSRLTETLTKLEEASKTAEESERGRKDLEIRSIADDERLNQLEDQQKEAKYIAEDADRKYDEAARKLAIAEVDFKRAEARLEAAESKIVELEEELRVIGNNMKALEISEQESAQREESYEETIRDLTERLKAAEQRATEAERQVSKLQNEVDHLEDDLLAEKERYKALSGELDQTFAELTGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.