PharMolix/UniProtQA huggingface dataset:
Protein: IF1_CERS4
Sequence: MAKEDTLEFPGVVKELLPNATFRVELDNGHELIAVMAGKMRKNRIRVLAGDKVQVEMTPYDLSKGRINYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERI1_ASHGO
Sequence: MNDKVAATLVLVVTYSIVGASLWCLTYAWHDETKLYYWCIVQLLPVMLWVWCVISWCGAQLFGYAKRGKAD
What is the function of this protein?
Probable component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI-anchors for cell surface proteins.
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit, Endoplasmic reticulum-associated Ras inhibitor protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SBCC_STAAM
Sequence: MKPLHLKLNNFGPFLKEEIDFSKIDNNELFLISGKTGSGKTMIFDAMTYALFGKASTEQREENDLRSHFADGKQPMSVTFEFQLNHRIYKVHRQGPYIKEGNTTKTNAKFDVFEMVDGKYEIRESKVISGTQFIIELLGVNADQFRQLFILPQGEFKRFLISNSREKQGILRTLFDSEKFEAIREILKEELKKEKAQIENRYQQIDLLWQEIESFDDDKIKGLLELATQQIDKLIENIPLLQARSKEILAFVNESKETAIKEYEIIEKKTLENNILKDNINQLNKNKIDFVQLKEQQPEIDEIEAKLKLLQDITNLLNYIENREKIETKIANSKKDISKTNNKILNLDCDKRNIDKEKKMLEENGDLIESKTSFIDKTRVLFNDINKYQQSYLNIECLITEGEQLGDELNNLIKGLEKVEDSIGNNESDYEKIIELNNAITNINNEINIIKENEKAKAELDKLLGSKQELENQINEETTIMKNLEIKLDHYDKSKLDLNDKESFISEIKSAVKIGDQCPICGNEIQDLGHHIDFDSIAKRQNEIKEIEANIHAIKSNIAVHNSEIKFVNEKISNINIKTQSDFSLEVLNKRLLENENALNNQRDLNKFIEQMKEEKDNLTLQIHNKQLRLNKNESELKLCRDLITEFETLSKYNNITNFEVDYKKYVQDVNQHQELSKEIEDKLMQLSQRKLIEQNNLNHYENQLETYNNDLELNEQSIEMEMSRLNLTDDNDINEIIAWRGEQEELEQKRDTYKKRYHEFEMEIARLESLTKDKELLDSDKLKDEYEQKKEKMNTLIDEYSAVHYQCQNNINKTQSIVSHINYLNQELKDQQEIFQLAEIVSGKNNKNLTLENFVLIYYLDQIIAQANLRLATMSDNRYQLIRREAVSHGLSGLEIDVFDLHSNKSRHISSLSGGETFQSSLALALGLSEIVQQQSGGISLESIFIDEGFGTLDQETLETALDTLLNLKSTGRMVGIISHVSELKNRIPLVLEVKSDQYQSSTRFKRN
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: RL14_LACLM
Sequence: MIQTESRLKVADNSGAKELLTIRVLGGSSRKFAGIGDIVVATVKSAAPGGAVKKGEVVKAVIVRTKSGAKRPDGSYIKFDENAAVLIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y261_STRPQ
Sequence: MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAIREMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK
What are the official names of this protein?
UPF0154 protein SPs1598.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TYSY_MYCBO
Sequence: MSIVTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEYTYEDIVVKNYDPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_METJA
Sequence: MKVLDEIVANRKKMVEIEKRKDIIKNLRSFIDELDIDVEKKRKLRLSKAIKKAKEIKNPIITEIKPSSPSKGSIREINLEDVKNIANEMVEGGATALSILTEPKYFNGSYKNLIVAREFDIPILMKDFIVDFYQIDVASEIGANAVLLIVSSLKEDIGEFLDYAKENDLECLVETHSEDEIDIALDAGAKIIGINNRDLKTLKIDLSTTEKLAPLIPKNKIKVGESGIYTKEQLNYVLKFTDAALIGSSIMESENIREKVREFVIK
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LRKS5_ARATH
Sequence: MRFSLAWKLLFLILTCKIETQVKCLKFDFPGFNVSNELELIRDNSYIVFGAIQVTPDVTGGPGGTIANQAGRALYKKPFRLWSKHKSATFNTTFVINISNKTDPGGEGLAFVLTPEETAPQNSSGMWLGMVNERTNRNNESRIVSVEFDTRKSHSDDLDGNHVALNVNNINSVVQESLSGRGIKIDSGLDLTAHVRYDGKNLSVYVSRNLDVFEQRNLVFSRAIDLSAYLPETVYVGFTASTSNFTELNCVRSWSFEGLKIDGDGNMLWLWITIPIVFIVGIGAFLGALYLRSRSKAGETNPDIEAELDNCAANPQKFKLRELKRATGNFGAENKLGQGGFGMVFKGKWQGRDIAVKRVSEKSHQGKQEFIAEITTIGNLNHRNLVKLLGWCYERKEYLLVYEYMPNGSLDKYLFLEDKSRSNLTWETRKNIITGLSQALEYLHNGCEKRILHRDIKASNVMLDSDFNAKLGDFGLARMIQQSEMTHHSTKEIAGTPGYMAPETFLNGRATVETDVYAFGVLMLEVVSGKKPSYVLVKDNQNNYNNSIVNWLWELYRNGTITDAADPGMGNLFDKEEMKSVLLLGLACCHPNPNQRPSMKTVLKVLTGETSPPDVPTERPAFVWPAMPPSFSDIDYSLTGSQINSLTELTGR
What are the official names of this protein?
Probable L-type lectin-domain containing receptor kinase S.5, LecRK-S.5.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PURL_CAMJJ
Sequence: MDKETIKAHKISDEEYAQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGQGMAAVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVAGLNSLKFGDIHDEKCGKHQKYLVKGVVNGISHYGNCMGVPTIGGECAFDECFNGNILVNAFALGVCKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGDPFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPMRESGMTPYELMLSESQERMLICAKKGYEDKVIEIFKKWDLDAVVMGEVTNTGKMELFWHDELVGLIPIEPLSEKAPILSRPTSEPKYLSEIKNYKFELKSSVQELFIQMLQNENINNKAFIYDQFDSSVQTNTIKADGRLGASVIRIKENGASVAMAIECNSRLNYVNPKIGAALAVASAGRKVACTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVSIYPSPTIVSVGVLEDANKTLKASFEKENLSVYLLGESLGEFSGSMVMKIQDKKVSGSLKELDYKAELALWDLLYKANQNSLLECANSVGIGGIAMTLAKMFAISSVGANLTSDFDDEKMIFDESASRAIIGLSKENEEAFLNLAKEFGVKAYKLGVSTSQKHFKLDSIELSKAELDKLYFESFKEQIQ
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_CLONN
Sequence: MAKTFKLKIVTPEKIFFEGEAEKINLETTEGKTEILANHSAFIAMLVPTNSKLITDKGEEKKFFLSSGILKVNTEEVVILCDAAEWPEEIDKKRAEEAKKRAEERLSKKDGVDIKRAEFALMRAIKRIEMV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HEM1_SYNP2
Sequence: MNIVVVGLSHKTAPVEIREKLSIQEAKMDEAIAHLKSYPHVEEVAVISTCNRLEIYAVVQETEQGVREICQFLAETGQLQLNRLRRYLFTLLHQDAIRHLLRVAAGLESLVLGEGQILAQVKAAHKLGQQHKGLGRLLDRMFKRAITAGKRVRSETNIGTGAVSISSAAVELAQMKVKDLSNQKIAIIGAGKMSRLLVQHLVSKGAEDITIVNRSERGARDLAKKFPDVDLQLELLPEMLNVVEQADIVFTSTGATEPILDRAKLENLDLHTLILIDISVPLNVAADVEEIAGVRLYNVDALKEVVAQNQASRRKMAEEAEALLEEEVENYIQWWQSLETVPTISSLRSKVESIREQELEKALSRLGAEFEEKHQEVIETLTRGIVNKILHDPMVQLRAQQDIEARRVCLQSLQMLFNLETEEAI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RS17_BORBR
Sequence: MSETQNTQVAKRQRTLVGKVVSNKMDKTVVVLVERRVKHPIFGKIIMRSAKYKAHDESNQYNEGDTVEIAEGRPISRSKAWRVVRLVEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PSTB_HAEI8
Sequence: MISLQETKIAVQNLNFYYEDFHALKNINLRIAKNKVTAFIGPSGCGKSTLLRSFNRMFELYPNQKATGEINLDGENLLTTKMDISLIRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSKEKMNERVEWALTKAALWNEVKDKLHKSGDSLSGGQQQRLCIARGIAIKPSVLLLDEPCSALDPISTMKIEELITELKQDYTVVIVTHNMQQATRCSDYTAFMYLGELVEFGQTQQIFDRPKIQRTEDYIRGKMG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DXS_PROM0
Sequence: MLLSELSHPNQLHGLTVSQLEEIACQIRERHLQVVSTSGGHLGPGLGVVELTLALYQTLDLDFDKVVWDVGHQGYPHKLITGRFSQFDSLRQQNGVAGYLKRSESKFDHFGAGHASTSISAALGMAIARDRKGDNYKCVAVIGDGALTGGMALEAINHAGHLPNTPLVVVLNDNDMSISPPVGALSSYLNKVRVSPPLQFLSDSVQESVKNIPLIGKDIPEELKNIKGSVRRLSVPKVGAVFEELGFTYMGPIDGHDIGNLVKTFNAAHKLKRPVLVHVVTTKGKGYPYAEADQVGYHAQSAFDLTTGKSIPSKKPKPVSYSKIFGQTLLKICEQDSKVVGITAAMATGTGLDILQKNIPDQYIDVGIAEQHAVTLAAGMSCDGLKPVVAIYSTFLQRAFDQLIHDVGIQNLPVSFVLDRAGIVGADGPTHQGQYDISYMRSIPNFVLMAPKDESELQRMLITSINHNGPTALRIPRGSGLGVAIMDEGWEPLNIGEAEIIEGGEDILIIAYGSMVASAIETAKILKNMNINACIVNARFVKPLDKNLIMPLASRIQKVVTMEEGTLIGGFGSAIVELFNDNEINIPVYRIGIPDVLVDHASPDQSKEKLGLMPDQMADNIVKKFKLVN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RPOC_MESHJ
Sequence: MNTKVSRQYAKISENSIQKISLALATPEDVLEWSRGEVHRPETINYKTFKPERGGLFDELIFGPLVDYKCSVCGRKYRKSNENQLCIATKECKIRGSRILSKMARRYSMGHIALNAPILHFWFFKIDHSIIAKLLGLKVFEGNSKVPTTITKAAIENLIYYKSHIVLETGGLKSLEQNKIIDISEAGLIYKNALIEIIEFYPPGSEEHNALAESISELADVTSSKIGREYGVDYYELNEIIEEFSSARIATGALAIEYLLDKIDLRAEKAAVEAELAGVQKQIYKNKKIILKNQKRDKLYKRLQVINAFINSGQDPKMMIIRNLPVIPADLRPLVQLDGSRHSTSDCNELYRRIIIRNNRLKRWKAAHAPVIIIQNEMRMLQEAVDALIDNQKKSTNQVTTKEGRPLKSISDALTGKKGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQAGLPRKMAAVLFEPWIIRNLIQEKKVGSIKMARKMIEEENPIIWPHVAKVIQNKPIILNRAPTLHRLSIQAFEPVLVRAKAIQLHPLVTAGFNADFDGDQMAVHIPISPEAIRETQELMFADKNILGPKDGEPIVNPSQDMVLGLYYLSQEKAGAKGEGSFFSTYEAMLKAYEFRSVELHARVVLPFEQVKPFIAKTMRGHLISTVGKFILNNIFPANFPFIFDDNVDELELNYPSQIKKYVLPYGTNFREYIQNLKVNEPLNKKAIAKIVRQIFDTYDGLLAKEDIATVIDQLDFGNYQNCVLRYEKLRDYKKQKLPVPHLSKLSEFTIFEYSQLYKQLQQNGPVESYRVLEDHEKAELLEKIWFKYNNMVCSILDKIKDLGFHYSTLSGTSIAISDIKMAPKKHEFIKEGENYINKLNTFYAKGLITDDERYVLAIAKWTQIKNDIQEDLNQSIKDDNQNSLVMMMKSGARGNISNFVQLAGMRGLMANNVKALKVDAENERVVRSIVEVPVKSSFLEGLTSFEFYSSTHGARKGLTDTALNTAKSGYLTRRLVDVAQNIVVVAEDCFSDFGFVVKDIIDTKTNTIIVPLLERIEGRFLNKDVYDSRGIKLASAGTMVDLQTAKKIVAAGIKKVEIRSILSCHIKNSVCKKCYGKDLATNRLVSIGEAVGIIAAQSIGEPGTQLTMRTFHTGGVANVEDITGGFTRLIELIDSHEHPWGKPAKISPYYGIITKISDLAEKNAANKGFLITIEYKTSKNEKAEHIIRIEQSQKLRVKVGDKVIPGQKLVEGPIILKELLAVSDARTLQNYLLKEIQRIYRMQGISISDKYIEIIIRQMLSKVQIIENGDSNFFIGSIVDISDYQEVNGQLISQNKNPAFGNVIVKGAKQIPLLSNSFLAAASYQETSKILVHSVISSQIDKLEGLKENIIVGHKIPAGTNSNYEPKSKFDIRNPLSFFMKNNR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: HLX_HUMAN
Sequence: MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGDLGAAPEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEPAQGALGCL
What is the function of this protein?
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression.  Involved in embryogenesis and hematopoiesis (By similarity).
What are the official names of this protein?
H2.0-like homeobox protein, Homeobox protein HB24, Homeobox protein HLX1.
What is the protein family that this protein belongs to?
Belongs to the H2.0 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FADB_SHEAM
Sequence: MIYQSPTIQVELTADKIARLCFNAPGSVNKFDRETLASLNAALDVLKDSDAKAAVLTSGKDTFIVGADITEFLALFAEEDAKLMEWIAQANVVFNKLEDLPFPTVSAIKGFALGGGCEAILATDFRVADTSAKIGLPETKLGLIPGFGGTVRLPRLIGADNALEWITTGKDQRPEDALKVGAIDAVVAPENLEAAAIQMLNDALAGKLDWQARRARKQAPLTLPKLEAMMSFTTAKGMVYAVAGKHYPAPMAAVSVVEQAAGMSRAEALVVEHNAFIKLAKTDVATALIGIFLNDQLVKGKAKKASKLAKDIKHAAVLGAGIMGGGIAYQSASKGTPIVMKDINQAALDLGVNEAAKLLSAQVARGRSTPDKMAKVLNNITPALDYAPLKDVNVVVEAVVENPKVKAMVLADVENVVADDAIIASNTSTISIDLLAKSLKNPARFCGMHFFNPVHKMPLVEVIRGKDTSEETVASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLADGGDFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMADGFPDRMGKSDKDAIDVMYEAGRLGQKNGKGFYQYSIDKRGKPKKDVDPASYTMLAEAFGAQKAFEADEIIARTMIPMIIETVRCLEEGIVASPAEADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYAHLGGLYQVTDAMRELASNNGSYYPKA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: YIDD_CHRSD
Sequence: MRPGKRRPLTRLPFALLSWGMIGLLRVYQYGISPLLGPRCRFWPSCSQYAVEAIQVHGPLKGAWLALKRIVKCHPGHPGGVDPVPPGPHETPRKTSTHDDEPPSR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: METE_ECOHS
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHNVKPVLLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: IOLE_CLOPE
Sequence: MFNSNVKLGIAPIAWTNDDMPDLGKENTFEQCISEMALAGFKGSEVGNKYPRDVEVLKKALELRDMEIASAWFSAFLTTKPYEETEKAFIEHRDFLNAMGAKVIVVSEQGHSIQGQMETPIFDGKYVLNEEEWKTLAEGLNKLGALAKEKGMKLVYHHHMGTVVQTTEEIDKLMDLTDENLVYLLFDSGHLVYSGEDALEVLKKYVNRVKHVHLKDIRKKKVEEVKRDKLSFLQGVRKGAFTVPGDGDIDFEPIFKVLDDNNYEGYLLVEAEQDPAIANPLEYAIKARKYIKEKTNL
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: Y487_MYCBO
Sequence: MKALVAVSAVAVVALLGVSSAQADPEADPGAGEANYGGPPSSPRLVDHTEWAQWGSLPSLRVYPSQVGRTASRRLGMAAADAAWAEVLALSPEADTAGMRAQFICHWQYAEIRQPGKPSWNLEPWRPVVDDSEMLASGCNPGSPEESF
What are the official names of this protein?
Uncharacterized protein Mb0487.
What is the protein family that this protein belongs to?
To M.leprae ML2452.
Protein: FBL19_ARATH
Sequence: MEVNGGEGKVEMGSGLYPDWSELTRECLLDIFSRLSQEQRWIGPMLVSKNWMNACYDPTLNTIFDLETRFLSFPESINWWTPEFEDKVDSFLRSVVDRSEGGLTEIRIRHCTERSLSYAAERCPNLEVLWIKNCPNVTDASMEKIAMNCPNLRELDISYSYGITHESLITLGRSCQNLKILKRNLLPRLGPSLPTIVAPLDYLATFPRYGNIEARIIGKYMTQLKHLEIRYSTLTARGLDSVCKGCSNLEYMDLRGCISLTRSDINTNTSGLKNLTEIIKPDFNPPIAVLRVPRPGNPREE
What are the official names of this protein?
Putative F-box/LRR-repeat protein 19.
Protein: RS18_STRMK
Sequence: MSKFFRRRKFCKFTAEGVKEIDYKDLNTLRQYLTENGKIVPSRVTGTKSKYQRQLATAVKRARFLALIPYTDNHDV
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y566_SACD2
Sequence: MNEWLNVAPELLALLIFVSRVIDVSLGTFRTIVIFRGYKALAAFIGFFEIMIWLVAAGQVFKNLDQWYLALAYAGGFSMGNYVGMWIENRFAIGNELVRCLSFNRDVLAEKIREQGFKVISFDGDMGTDKLVELLFIVEKRRNVPALIKLIKELDASAVYSVSDVKSVYEGPEPLPRRLFFR
What are the official names of this protein?
UPF0316 protein Sde_0566.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL33_HALHL
Sequence: MAGKSAREKIKLVSSAGTGHFYTTDKNKRNTPHKLEMKKYDPVVRKHVTYRETKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MSCL_SALHS
Sequence: MSFIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAFTLREAQGDIPAVVMHYGVFIQNVFDFVIVAFAIFVAIKLINRLNRKKAEEPAAPPAPSKEEVLLGEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VL1_HPV10
Sequence: MAGISIFGLLPFTSPDIVAVNVSHIFLQMALWRSSDNLVYLPPTPVSKVLSTDDYVTRTNIYYYAGTSRLLTVGHPYFPIPKSSNNKVDVPKVSAFQYRVFRVRLPDPNKFGLPDARIYNPDAERLVWACTGVEVGRGQPLGVGLSGHPLYNKLEDTENSNIAHGPIGQDSRDNISVDNKQTQLCIIGCTPPMGEHWGKGTPCRNPPAQGDCPPLELITSPIQDGDMVDTGYGAMDFTALQLNKSDVPIDICQSTCKYPDYLGMAAEPYGDSMFFYLRREQLFARHFFNRASAVGDAIPDTFILKSNGGGRDVGSAVYSPTPSGSMVTSEAQLFNKPYWLRRAQGHNNGICWANQLFVTVVDTTRSTNMCLCVPSEASPATTYDATKFKEYLRHGEEYDLQFIFQLCKVTLTPDIMAYLHTMNSSLLEDWNFGLTLPPSTSLEDTYRFLSSSAITCQKDTPPTEKQDPYAKLNFWDVDLKDRFSLDLSQFPLGRKFLLQLGVRSRSAVSVRKRPATSATGSTAAKRKRTKK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RS14_CHLT2
Sequence: MAKKSAVAREVKRRKLVEANFQKRAELRKLAKSLSVSEEERERAREALNKMRRDTSPSRLHNRCLLTGRPRGYLRKFAISRICFRQMASMGDIPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: PAX_I68A5
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIMVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFVSPKEAKKQLKKDLKSQGQCAGLPTKVSRRTSPALRILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.