PharMolix/UniProtQA huggingface dataset:
Protein: NQRB_NEIMB
Sequence: MGLKHFLEKIEPHFLPGGKHEKWYALYEAAATIFYTSGAVTRKAAHVRDALDSKRMMILVWLALFPAMFYGMYNVGAQAFGALTPDLLQQNIANDWHYAFANALGINMSSEAGVSDKMLFGAIYFLPIYATVFVVGGFWEVLFATVRKHEINEGFFVTSILFALIVPPTLPLWQAALGISFGVVVAKEVFGGTGKNFMNPALAGRAFLFFAYPANLSGDAVWTAVDGYSGATALAQWAAHGADGLKNAVTGQTITWMDAFIGKLPGSIGEVSTLALLIGGAFIVFARIASWRIIAGVMIGMIAMSSLFNFIGSDTNAMFAMPWYWHLVVGGFAIGMLFMATDPVSASFTNVGKWWYGALIGVMCVLIRVVNPAYPEGMMLAILFANLFAPIFDYFVAQANIKRRKARSNG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH602_AZOC5
Sequence: MAAKDVKFAGDAREKMLRGVDILANAVKVTLGPKGRNVVIEKSFGAPRITKDGVSVAKEIELEDKFENLGAQLVREVASKTNDLAGDGTTTATVLAQAIVKEGSKAVAAGMNPMDLKRGIDLAVDAIVKDLAAKAKKVTSNAEIAQVGTISANGDADVGKFLAEAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNAEKMRVEFEDPYILIHEKKLSNLQELLPVLEAVVQSGKPLVIVAEDVEGEALATLVVNKLRGGLKVAAVKAPGFGDRRKAMLQDIAILTGGQAISEDLGIKLENVNLSMLGRAKKVVIEKENTTIVDGNGEKADIEARVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKEKKDRVDDALHATRAAVEEGIVPGGGVALLRAIKVLEGLKVENTDQKTGIDIVRRAIQAPARQIVANAGDDGSVVVGKILENETYTFGYNAQTGEYVDMVASGIIDPAKVVRTALQDAASISALIITTEALVVELPKKAAAAPAMPGGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCS_PSEF5
Sequence: MKLPIYLDYSATTPVDPRVAQKMSECLLVDGNFGNPASRSHVFGWKAEESVENARRQVADLVNADPREIVWTSGATESDNLAIKGVAHFYHTKGKHLITSKIEHKAVLDTMRQLEREGFEVTYIEPGEDGLITPAMVEAALRDDTILVSIMHVNNEIGTINDIAAIGELTRSKGVLFHVDGAQSTGKVDIDLQALKVDLMSFSAHKTYGPKGIGALYVSRKPRVRLEATMHGGGHERGMRSGTLATHQIVGMGEAFHVAKEDMAAENLRIKALSDRFYKQVEHLEELYINGSMTARVPHNLNLSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFTFGRFTTEEEIDYAAQKVCEAVTKLRALSPLWDMYKDGVDISKIEWAAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL39_ASHGO
Sequence: MAAKKSFKIKQKLAKAKNQNRPLPQWFRLKTNNTIRYNAKRRHWRRTKMGI
What are the official names of this protein?
60S ribosomal protein L39.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: RUVA_STRPB
Sequence: MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEALLALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: DXO1_YEAST
Sequence: MSTEQDAVLGLAKDLEGINLLTVPNLERGHQSKLCKEKTTSDSSSSRKPSQQRDNYRKRRPKLICIPYTSFLHTGMHNFLTKPPRDIFHESKEVALFTNGRAYTILRKDLIPNLKESIAELYESSLLEAKKRKVPYLGHDLFANIDEFVPMTISELDSVSPCFSYIENWILDNPGKDFKIGKKFTVVTTRHHIVDLTMHLFNRRNRQTSLIVTYMGAGLLSFCRNVKKDSQMSKEGIYSNDPNMKKICYSGFEFENWVTENSKVADLTGSKCPIFSLVESKLSEEIGLLIRCEMDAFNPVSETNTELKCFAPLSMHNSNHRRKLLKTWVQTGLLPNSDIMIGLRDSHSGQLLDIQWYSRDLLCKKFNHPGLPTNKKELNYNAQIAVEWCHYCIEAICKLVEANISDYSSTKPESFEIGIDTNNAIVITKLKTTPRNVELFGM
What is the function of this protein?
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity).  The NAD-cap is present at the 5'-end of some RNAs and snoRNAs.  In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (PubMed:22961381).  Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (PubMed:22961381).  Also has 5'-3' exonuclease activity (PubMed:22961381).
What are the official names of this protein?
Decapping and exoribonuclease protein 1, 5'-3' exoribonuclease DXO1, NAD-capped RNA hydrolase DXO1, DeNADding enzyme DXO1.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
Protein: PSTS_STAA8
Sequence: MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDHSDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTVAVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVMNKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKKTIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQLDDLKAFIDKNQKSDDKKSDDKKSEDKK
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ACTNA_DICDI
Sequence: MSEEPTPVSGNDKQLLNKAWEITQKKTFTAWCNSHLRKLGSSIEQIDTDFTDGIKLAQLLEVISNDPVFKVNKTPKLRIHNIQNVGLCLKHIESHGVKLVGIGAEELVDKNLKMTLGMIWTIILRFAIQDISIEELSAKEALLLWCQRKTEGYDRVKVGNFHTSFQDGLAFCALIHKHRPDLINFDSLNKDDKAGNLQLAFDIAEKELDIPKMLDVSDMLDVVRPDERSVMTYVAQYYHHFSASRKAETAGKQVGKVLDTFMLLEQTKSDYLKRANELVQWINDKQASLESRDFGDSIESVQSFMNAHKEYKKTEKPPKGQEVSELEAIYNSLQTKLRLIKREPFVAPAGLTPNEIDSTWSALEKAEQEHAEALRIELKRQKKIAVLLQKYNRILKKLENWATTKSVYLGSNETGDSITAVQAKLKNLEAFDGECQSLEGQSNSDLLSILAQLTELNYNGVPELTERKDTFFAQQWTGVKSSAETYKNTLLAELERLQKIEDSLVEFAKRAAQLNVWIEAADDHVFDPINVDSVQGVQEIQEKFDAFLHDQSQQFAELEALAALTQQLRELGRSENDYSVISYDELSAKWNNLLAGIEERKVQLANELTTQTNNDVLCQSFSVKANEISDYVRVTLDAISQNTSSDPQEQLNNIRAIITAHAEKKPELDELYTIASQLEEAQVVDNKHTQHSLESIKLKWDKLNTLAKKNEQVVEGEILAKQLTGVTAEELSEFKACFSHFDKDNDNKLNRLEFSSCLKSIGDELTEEQLNQVISKIDTDGNGTISFEEFIDYMVSSRKGTDSVESTKAAFKVMAEDKDFITEAQIRAAISDSKQIDYLLASMPAVEGGFDYNSFAEKLYQ
What is the function of this protein?
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures.  This is a bundling protein.  Increases the actin-stimulated ATPase activity of myosin.  Involved in vegetative cell growth, phagocytosis, motility and development, probably through stabilization of the actin network in the cortical cytoskeleton.
What are the official names of this protein?
Alpha-actinin A, Actin-binding protein A, F-actin cross-linking protein.
What is the protein family that this protein belongs to?
Belongs to the alpha-actinin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Contractile vacuole. Cytoplasmic vesicle, phagosome. Note=Expressed diffusely throughout the cytoplasm. Accumulates in the cell cortex, contractile vesicle and phagosome.
Protein: YTFE_YERPB
Sequence: MDYRNQSLGALAIAIPQATKLFRQHQLDFCCGGKQTLLRAANKLNLDIDALEAQLSALQTEPHSSEDWQQQPLTNLISFIISRYHDRHREQLPELVLMAEKVERVHGEKPTCPRGLAAELSAILEELTQHMYKEEQILFPMIQRGMGSQASGPIFVMEAEHDAVGQQLEVVKQLTQNVTPPEGACNTWRALYTGINEFITDLMEHIHLENNLLFPRALRGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK20_OLIPU
Sequence: MTRIKRGYIARRRRTKLRLFASSFRGAHSRLTRTMTQQRIRALVSAHRDRGKRKRDFRRLWITRINAVIHEMGVFYSYNQFIHNLYKKQLLLNRKILAQIALLNRSCLYTISNDIKK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS14_YERP3
Sequence: MAKQSMKAREVVRVKLANKYRAKREELKAIISGVNSSDEDRWDAVLKLQSLPRDSSPSRQRNRCNQTGRPHGFLRKFGLSRIKVRETAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: HSCA_BURL3
Sequence: MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRNSVPEVLPDEAGRVLLPSVVRYLEKGGRRIGHEAKEQAATDPRNTIVSVKRFMGRGKAEVEGAANAPYEFVDAPGMVQIRTIDGVKSPVEVSAEILATLRYRAEDSLGDDLVGAVITVPAYFDEAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNGSEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDFDHALFGHVLAQAGIDVKTLAPEDVRLLLDRVRVLKEALSSAPQASLDVTLSGGAHLVQTISHDTFASLVEPLVQRTLTPTRKALRDAQVTSADIKGVVLVGGATRMPVIRDAVAKYFGQPPLVNLDPDQVVALGAAIQADLLAGNRGTGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPIARAQEFTTFKDGQTAMAIHVVQGERELVADCRSLARFELRGIPPMTAGAARIRVTYQVDADGLLSVFAREQLSGVEASVVVKPSYGLADDDIAKMLEDSFKTAEIDMRARALREAQVEAERMLEATQAALAADGELLDADERTQVDTLAAALRAVAQGDDTNAIEAATKALAEGTDEFAARRMDKSIKRALSGRRLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HIS6_METC4
Sequence: MLKTRIIPCLDVKDGRVVKGVQFLELRDAGDPVESAKAYDAAGADELCFLDITASHEARGTLLDVVSRTAEACFMPLTVGGGVRTVADVRTLLLAGADKVGINTAAVKNPDFVAEAAEKFGDQCIVVAIDAKRVSGPDEAARWEIFTHGGRNPTGIDAVEFARTVSERGAGELLVTSMDKDGTRSGYDLALTRAIADAVRVPVIASGGVGGLDDLVAGVRDGGASAVLAASIFHFGQHTVGEAKAHMAAAGLAMRLDP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2_YEAS1
Sequence: MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINKLNDGSITLENAKYETVHYLTPEAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDALINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTSNLPSFKKADHSRQPIVKETDSFKPPSFKMATEPKVYRVVDDLIEDSDDDDFSSDSSKAQYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEGKEINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFKPGQPINLDSISDDL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: RECJ_DICD3
Sequence: MNVVTQLRRRPTAETELPDSLPALLRRLYAQRGVRQMQELERSLRGLLDYRLLGGITQAVEVLRQALADNRRIVIVGDFDADGATSTALTVLALRSMGGREVQYLVPNRFEDGYGLSPEVVAQAAAKGAELIVTVDNGISSHAGVDDAHRRGIAVVVTDHHLPGETLPAAEAMINPNLSDCAFPSKALAGVGVAFYLMMALRANLRECGWFAERGLAEPNLAELLDLVALGTVADVVPLDANNRILISQGLSRIRAGKCRPGIRALLEVSNRDAAQLVASDLGFALGPRLNAAGRLDDMSVGVELLLCNDIVQARMLASDLDALNQSRREIEAGMQVEALHLCEQLERSRDTLPLGLAMYHPQWHQGVVGILASRIKERFHRPVIAFAPAGDGILKGSGRSIAGLHLRDALERLDTCHPGLMLKFGGHAMAAGLSLVEDRFDEFRQRFADLVGEWLDASQLEGVVWSDGELASPELTLGTAEMLREAGPWGQAFPEPTFDGRFRLLQQRLVGERHLKVMVEPLGGGPLLDGIAFNVDTLLWPDSSVREVELAYKLDVNEFRGKRSVQLLIEHLWPL
What is the function of this protein?
Single-stranded-DNA-specific exonuclease.  Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available (By similarity).
What are the official names of this protein?
Single-stranded-DNA-specific exonuclease RecJ.
What is the protein family that this protein belongs to?
Belongs to the RecJ family.
Protein: CLF1_NEUCR
Sequence: MESSRGPPRVKNKAPAPVQISAEQLLREAVDRQEVNLQTPTQRFADLEELKEYQGRKRKEFEDYVRRNRVRLSNWLQYAQWELEQKEFARARSVFERALDVHPNNTQLWIRYVQAEIKNRNINHARNLLDRAVTRLPRVTSLWYQYLYVMEMLGDIPGTRQVFDRWMKWQPDEQAWSAYIRLEKRYGEFDRAREIFRAFTAVHPEPRTWLKWAKFEEEYGTSDTVREVFQTAIQTIAETLGDDAVDERIFIAFARYEARLREYERARAIYKFGLDNLPRSKSMTLHAHYTTFEKQFGDKEGVEDVILTKRRRLYEEQVKENAKNYDVWFDFARLEESGGDVDRTREVYERAIAQVPPTQEKRHWRRYIFLFLFYAIWEERETKDIGRARQIYDTCLNLIPHKKFTFAKVWVAKAHFEIRQGQLTTARKTLGRAIGMCPKDKIFKEYILLEQKLYEFERCRTLYEKHVMYNPANCQTWIKWAELERGLDDLERTRAIFELAVSQPILDMPEVVWKAYIDFEEEEGEYERTRALYERLLEKADHPKVWISYAQFEINIPDEAEEEEETEEEVEEKPVSEEAKARARKIFERAHKSMKERELKAERVSLLNAWLAFEKTHGSAEDIEKIQKQMPRKTKKKRKLEDDTWEEYVDYIFPADDQQTKNLSSLLAMANAWKQQAAGGAGGAAVDEAAQGGSS
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle progression.  Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor clf-1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL23_BUCAI
Sequence: MISEERLLKILLSPHVSEKTSISMEKFNTVVLKVLNNATKYEIKYAVKKIFDVDVDSIKTLKVKGKKKRQSNRIIQRSHWKKAYIKVKKGCNLDFIGNTE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: UFO_HUMAN
Sequence: MAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVPLGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDAVPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWPWWYVLLGAVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTELREDLENTLKALPPAQEPDEILYVNMDEGGGYPEPPGAAGGADPPTQPDPKDSCSCLTAAEVHPAGRYVLCPSTTPSPAQPADRGSPAAPGQEDGA
What is the function of this protein?
(Microbial infection) Promotes Zika virus entry in glial cells, Sertoli cells and astrocytes (PubMed:28076778, PubMed:29379210, PubMed:31311882).  Additionally, Zika virus potentiates AXL kinase activity to antagonize type I interferon signaling and thereby promotes infection (PubMed:28076778).  Interferon signaling inhibition occurs via an SOCS1-dependent mechanism (PubMed:29379210).
What are the official names of this protein?
Tyrosine-protein kinase receptor UFO, AXL oncogene.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MMM1_PYRTR
Sequence: MADEVPTAVPLATPAGSSSLSFTQGFLLGQLSIAILIFCFIKFFIFGEPPSADDRALHLNSLRRARTLAHQQSYKQLRTRANSTSLSLRHKPSTSIIRKGEETRGGPSIATILAKTYYNVKGHQPESLDWFNVLIAQTIAQLRADARQDDAILTSLTEVLNTGSKPDWIGEIKVTEIALGDEFPIFSNCRVMPAEDGFWYGPGSTGNDKERLQARMDVDLSDVITIGVETTLNLNWPKPMSAVLPVALAVSIVRFSGTLAMSFIPSSSPPSTTAPMPSPTSNTHRSSSPSRPASSSGAPPHRPTTLAFTFLDDYRLDLSVRSLVGSRSRLQDVPKIAQLIESRVHAWFDERAVEPRFQQIVLPSLWPRKHNTRGGAPEDTEAAAEGEEGLDEDDFAVVDGNGTAPGSTSYIPSPIAENVTLEERIEAEGAKMREAEIRAGVRKPSASQERSRGRDDRADGMRWRGALPR
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: VATE_METKA
Sequence: MGVEELERKILEDAEKEAEEILEEAKRDAERIREKAEREAEEVRREILDRARREAETRRRREIAQAKLEIRQERLRVKEEYIEKAIERAEEKIRELAEEGRKEYLEFLKRSAIEAVNAISSDEVVLRANENDLMLLDEMLSEIRDETGKDVELGEPVEAVGGVIAESKDGSEAYDNTVDARLRRRRSEIVRRVSETLFGG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: UBIG_RICCN
Sequence: MSSIDKKELEKFEKISHNWWNKDGEFGILHRINPIRLEYIIEKITTHYNRHLSKLTYREELVGNMQHSTAAYALVREDASSRLTHKLPLEAEFEKMSNDISKLEILDVGCGGGLIATPLAAQGFNVTAIDALQSNIETATAYAKENGVKINYLQSTIEELDSDKLYDVVICLEVIEHVENVQQFILNLVKHIKPNGMAIISTINRTKKAYILGIIVAEYILGWVPKNTHDYSKFLKPLEIYEMLTDTKIEIKELKGLVYDPAKNEWKLSDDIDVNYFMCLGRKSMCYPS
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: HINT_CAEEL
Sequence: MSEVDKAHLAAINKDVQANDTLFGKIIRKEIPAKIIFEDDEALAFHDVSPQAPIHFLVIPKRRIDMLENAVDSDAALIGKLMVTASKVAKQLGMANGYRVVVNNGKDGAQSVFHLHLHVLGGRQLQWPPG
What are the official names of this protein?
Histidine triad nucleotide-binding protein 1.
Protein: Y1815_LISIN
Sequence: MNQNPVEEGQKFPLTIRRMGINGEGIGYFKKAVVFVPGAITGEEVVVEAVKVRDRFTEAKLNKIRKKSPNRVTAPCPVYEACGGCQLQHVAYNAQLELKRDIVIQSIEKHTKIDPAKLKIRPTIGMEDPWRYRNKSQFQTRMVGSGQVETGLFGANSHQLVPIEDCIVQQPVTIKVTNFVRDLLEKYGVPIYDEKAGSGIIRTIVVRTGVKTGETQLVFITNSKKLPKKREMLAEIEAALPEVTSIMQNVNQAKSSLIFGDETFLLAGKESIEEKLMELEFDLSARAFFQLNPFQTERLYQEVEKALVLTGSETLVDAYCGVGTIGQAFAGKVKEVRGMDIIPESIEDAKRNAEKNGIDNVYYEVGKAEDVLPKWVKEGFRPDAVIVDPPRSGCDQGLIKSLLQVEAKQLVYVSCNPSTLARDLALLAKKYQIRYMQPVDMFPQTAHVETVTLLQRR
What are the official names of this protein?
Uncharacterized RNA methyltransferase lin1815.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: LPXC_WIGBR
Sequence: MIKQSTLKKSINIKGFGLHSGKPVKLTLNPAPVNSGIIYRRIDISPPVEFISNVNLIKNTNLCTSLENKNGVNISTVEHLSAAICGLGIDNIIIEITSSEIPIMDGSSWPFVDIIINSSGIKTLEHDKKFIYIKKIVRVEKEDKWIEVTPSNKFTLDFSIDFDHPVISSTSQNFFFTFSVNSFINQISKARTFGFLRDIKYLQSNKLALGGNCNCAIVIGNKRILNKEGLRFSNEFIRHKILDAIGDFFVSGYNIVGAFKAFKPGHNMHYMLLKKIFRNKNTWEFSTMKNNHSYVNNF
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RF1_CAMHC
Sequence: MLADRLKPFLKRYDEISESLSDPKILSDISLVTKLSKEQRSIEPVRNATLQYLEVLKNIEDNKSLINDTELGDLAKEELKNLEISQNKLEEEIKILLIPKDPNDEKNIFLEIRAGTGGDEAALFAGDLLDAYLRYAELRGYKTEIVSQSEGSAGGFKEVILLVKGDGAYSRLKFEGGTHRVQRVPETESQGRVHTSAITVAIMPEIEDSEIQINENDLRIDVMRASGHGGQCVNTTDSAVRITHIPTGLVVTNQDGKSQHKNKEAAMKVLKARLYDLQEKERKAKEQSERKDQVGTGDRSGRIRTYNYPQNRITDHRINLTLYRLDAIMAGGLFDEIIDPLIAHAQAEAINKSEI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.