PharMolix/UniProtQA huggingface dataset:
Protein: Y1183_CLOB8
Sequence: MKKINKDIGSFSEDLAKKYLEKNDYSILDCNFKNFLGEIDIICKKNTLLIIVEVKSRYNNNYGLPRESVNFSKQRSIIKVANSYINYKRLPNINVRFDVIEVYLNLESTNFKINHIKDAFRLN
What are the official names of this protein?
UPF0102 protein Cbei_1183.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: ADF1_MAIZE
Sequence: MANSSSGLAVNDECKVKFRELKSRRTFRFIVFRIDDTDMEIKVDRLGEPNQGYGDFTDSLPANECRYAIYDLDFTTIENCQKSKIFFFSWSPDTARTRSKMLYASSKDRFRRELDGIQCEIQATDPSEMSLDIVRSRTN
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers (By similarity).
What are the official names of this protein?
Actin-depolymerizing factor 1, ADF-1, ZmADF1, ZmABP1.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: RK20_PINTH
Sequence: MTRVKRGYIARKRRKKILAFVSGSRGAHSKLFRTANQRKARALVSAHRDRGKRKRDLRRLWITRINAAARANGVSYNRFIQYLYKRQLLPNRKTLAQIAVLDSNCFSTIFNNLSYDEIG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURG_ECOL6
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCUP_CHESB
Sequence: MAERKLLEALNGRTVFPPPIWLMRQAGRYLPEYRETRKKAGSFLDLCYNPELAVEVTLQPIRRFGFDAAILFSDILVIPHALGRDLRFEEGAGPLMSPIQANEIPGLDPNLIHNRLQPVYETVRRLRSELSEETALIGFCGAPWTVATYMIAGRGTPDQAPARLFGYRHPKEFSELLDTISAASADYLIRQIDEGADAVQIFDSWAGILDETSFDQWCLRPVAEIVRRVRERHPNVPIIGFPKGAGWLYSRYRQQTGVTALGLDWTVPLSEASRLQAEGPVQGNLDPMRLVAGGQALSKGVEDILSALGGAPFIFNLGHGITPETPIGHVEAMIQQVREGRL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_BURP1
Sequence: MARYIGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRISGARTSDYGTQLREKQKVKRIYGVLERQFRRYFAEADRRKGNTGETLLQLLESRLDNVVYRMGFGSTRAEARQLVSHKAITVNGIVANIPSQQVKAGDVVAIREKAKKQARIVEALSLAEQGGMPSWVAVDAKKFEGTFKQVPERADIAGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PCKA_COXBN
Sequence: MEQIAARVTYINLSPDELIQHAVKNGEGVLSSTGALAVTTGKRTGRSPKDRFIVKDEQTADQVAWGNINQPVEQRTFDQLWERALRYLSERAVYISHLQVGADDNYFLPLKVVTEFAWHNLFACDLFIRPSGDHANGKPSWVILSAPGLKTDPERDGVNSDGAVMINLSQRRVLLVGMPYAGEMKKAMFSVLNYLLPPHDVLPMHCAANAGQSGDVALFFGLSGTGKTTLSADPHRFLIGDDEHGWSATSVFNFEGGCYAKCIDLSQEREPMIWNAIRHGAIMENVVLDENGVPDYADARLTQNSRAAYPREHIPLRVENNRGRPPDAVLFLTCDLDGVLPPVALLTKEQAAYYFLSGYTALVGSTEVGSVKGVTSTFSTCFGAPFFPRPPTVYAELLMKRIEATGCQVYLVNTGWTGGAYGEGGERFSIPTTRAIVNAVLSGKLKEGPTEVLSGFNLTIPKSALGVDDHLLNPRKTWEDVSAYDARAQRLIQKFRENFEKFKVPAAIREAGPSDVH
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1419_MYCTO
Sequence: MGELRLVGGVLRVLVVVGAVFDVAVLNAGAASADGPVQLKSRLGDVCLDAPSGSWFSPLVINPCNGTDFQRWNLTDDRQVESVAFPGECVNIGNALWARLQPCVNWISQHWTVQPDGLVKSDLDACLTVLGGPDPGTWVSTRWCDPNAPDQQWDSVP
What are the official names of this protein?
Uncharacterized protein MT1462.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MYH1B_CHICK
Sequence: MATDADMAIFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVHAKESYVKSTIQSKESGKVTVKTEGGETLTVKEDQIFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGDKKKEEQPAGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPELIEMLLITTNPYDYQYVSQGEITVPSINDQEELMATDSAIDILGFTPDEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPGGTEVADKAAYLMGLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKSVFEKMFLWMVVRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPGKGKAEAHFSLVHYAGTVDYNITGWLEKNKDPLNETVVGLYQKSSLKTLALLFASVGGAEAESGAGGKKGGKKKGSSFQTVSALFRENLNKLMSNLRSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPIRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLMRVEFKKMMERRESIFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVSLLQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTADVGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESGEYSRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKAKKCPAHALQSARHDCDLLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQKNFDKILSEWKQKYEETQAELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKAIHELEKVKKQIEQEKSELQTALEEAEASLEHEEGKILRVQLELNQVKSDIDRKIAEKDEEIDQLKRNHLRVVDSMQSTLDAEIRSRNEALRLKKKMEGDLNEIEIQLSHANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLLQAEIEELRAALEQTERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLESDISQIQSEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLDQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRAKSREIGKKAESEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-1B, Myosin heavy chain 1B, skeletal muscle, Myosin heavy chain 3, Myosin-3, Myosin heavy chain, fast skeletal muscle, embryonic.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: HP1B3_BOVIN
Sequence: MATDTSQGELVHPKALPLIVGAQLIHADKLGEKVEDNTMPIRRAVNSTRETPPKSKLAEGVEEKPEPDVSSEESISTVEEQENETPPATSSETEQPKGQPENEEKEENKPSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQVKGKGASGSFVVVQKSRKPPQKSRNRKNRSSAVDPEPQVKLEDILPLAFTRLCEPKEASYSLIRKYVSQYYPKLRVDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQRCEKNGWMEQISGKGFSGTFQLCFPYYPSPGVLFPKKEPDDSKDEDEDEDEDDSSEEDSEDEEPPPKRRLQKKTPVKSPGKAAAMKQRGSKLAPKVPAAQRGKTRPLPKKAPPKAKSPAKKARPSPSVIKKPSGSSSKKPAASVRKEVKLPGKGKSTMKKSFKAKK
What is the function of this protein?
Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity.  May play a role in hypoxia-induced oncogenesis.
What are the official names of this protein?
Heterochromatin protein 1-binding protein 3.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=localized in nuclei but not in nucleoli in interphase. Colocalized with chromosomes in mitosis, with a gradually increased during G1 progression and a maximum level during late G1 phase (G1/S).
Protein: RL25_AZOC5
Sequence: MTAIKELKAVARARGGKGAARAERRAGRVPAVIYGEKQEPVTISLGHKEITRIIYAGHFLTTLFEIDVDGVKHRVIPRDYQLDPVKDLPLHVDFLRVSQGASVTVEVPVHFENQDKAPGLKSGGTLNVVAHAVALECPAEAIPDHVVADLTGLEIGDSLHLSKVKLPAGVSSAVTGDDTLATIVAPSGLKEAEADEAAAAAAAAAKA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PANB_LISW6
Sequence: MKRPVDFYAMKESGEKITMITAYDYPSAKNVEQAAADMILVGDSLGMVVLGYDSTVPVTIDDMIHHTKAVKRGAPNTFVVTDMPFMTYHGSVDETIQNARQIIQESGAHAVKLEGAGEVVNKIARLTEAGAPVVAHLGLTPQSVGLTGSYKVRAKSVQEAQELIDNALAVEAAGAIAIVLEAIPRQLAEKVTKALTIPTIGIGAGVETDGQVLVYHDIIGYGISRRAKFVKAYADIDETIEPALTSYVKEVKEQTFPEVKHSFTMAEEDLKGLYGRE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_DESHY
Sequence: MDFLNYPEPLADLITGLSRLPGIGPKTAGRLAFYLLQQPQVAENLAETMIRAQREIRQCSLCCNYTDHDPCPICTGEKRERTLLCIVEQPRDVVSLEKTREFKGLYHVLHGVISPLEGVGPEQLTISKLLGRLEGVQEVVMAMNPTVEGEATALYLSRLLKPLGIKVTRIAHGLPVGGDLEYADEITIARALEGRRQI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: LEUC_POLAQ
Sequence: MSRTLYDKLWDDHVVYSEEDGTATIYIDRQLLHEVTSPQAFEGLNLAGRPVWRISANLAVSDHNVPTTDRSEGIADPISKLQVDTLDQNCDAFGITQYKMNDTRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLLMKKSKNMLVRVDGRLQPGSTAKDIVLAVIGKIGTAGGTGYTIEFAGEAIRNLSMEGRMTLCNMAIEAGARAGLVAVDETTIEYIQGRPYSPKGPAMLQALQYWRTLHTDADAKFDAVVELRAEEIAPQVTWGTSPEMVLAISERIPDPEKERDPNKRSAMERALEYMNLTPNTPLSSITIDKVFIGSCTNSRIEDIRAAAKVVDRLGKKVAPNVKLALVVPGSGLVKAQAEREGLDRIFKAAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAIEGHFVDVRKIS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RL25_COXBN
Sequence: MAAESFELIAELREFTGKSAARRMRRFEDKVPGTVYGAGKAPQSITLLQKDLLKALESESTFSSILTLKVGDKKQKVILKALQRHHTKPKIVHIDFQRIKASEKLIMNVPLHFLGEDDCPGVEAGGVVSHLQSEVEIRCLPADLPEYIEVDLSHLQLDESVHLSNLKLPAGVGLTSAVDEEHDSPIASVHMPRVSKADVEAEAAEAALAKEAATEAAEEEETEKPASEAEASGEAEQADTDKKE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: KPRS_PROMP
Sequence: MTSFITAVDNEEPTFNLTNSRLRLVSGTSNPKLAEEIASYLGIENVPLVSKRFADGELYVQIQQSIRGCDVFLIQPTCAPVNDSLMELMIMVDACKRASARQITAVIPYFGYARADRKTSGRESITAKLTANLLEKSGVDRVLAMDLHSAQIQGYFDIPCDHIYGSPVLIDYLESLKLEEVVVVSPDVGGVARARAFAKLMSDAPLAIIDKRRSAHNIAESLTVIGEVKGKTAILIDDMIDTGGTICSGANLLKKEGAKRIFACASHAVFSPPSYERLSSKDLFEQVIVTNSIPVIDNYEFPQLKVLSVANMLGEAIWRIHEESSVSSMFR
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFRP_RAT
Sequence: MPYLLISTQIRMEVGPTMVGDEHSDPELMQQLGASKRRVLGNNFYEYYVNDPPRIVLDKLECRGFRVLSMTGVGQTLVWCLHKE
What is the function of this protein?
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1.  This inhibition is reversed by L-phenylalanine.
What are the official names of this protein?
GTP cyclohydrolase 1 feedback regulatory protein, GFRP, GTP cyclohydrolase I feedback regulatory protein, p35.
What is the protein family that this protein belongs to?
Belongs to the GFRP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus membrane. Cytoplasm, cytosol.
Protein: HIS1_CHLPM
Sequence: MSNSNRVLKLGLPKGSLQDSTIELFGNAGFHFSVQSRSYFPSIDDDELEAILIRAQEMAHYVELGAFDVGLTGKDWIIETGADVVEVADLVYSKASMRPVRWVLAVPENSPIKTVKDLEGKHIATEVVNITRKYLESNGVTAAVEFSWGATEVKPPDLADAIVEVTETGSSLRANKLRIVETILESNTKLIANKSSWDDPWKREKIESMALMLQGAINAQGKVGLKMNAPESALEAITAMIPALRQPTVSHLAHNQWVALEVIVLEREVRKLIPELKKAGAEGIFEYDINKLID
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE7_HPV28
Sequence: MHGPHPTVKDIELSLAPEDVPVQCNVQLDEEDYTNVEEPAQQAYRVVTLCPKCSSPLRLVVECSHADIRALEQLLLGTLTVVCPRCV
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: METAA_PARD8
Sequence: MPLNLQKNLPAIELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMPLKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMQEFYKDFDEMADDFYDGMIVTGAPVEQMPFEEVSYWEEITQIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAKMFGVFRHSLREPFVPIFRGFDDEFFVPHSRHTEIRREDIMKVPELTLLSESEESGVYMAMARGGREFFITGHSEYSPYTLNDEYMRDLGKGLPINKPRNYYRNNDPAQGPVVRWRGHANLLFTNWLNYYVYQETPFRREDIKKLGSL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBX4_ECHGR
Sequence: SRRERTIYTPEQLEAMEEVFGVNRYPDVSMREELASRLGINESKIQVWFKNRRAKLRNLE
What are the official names of this protein?
Homeobox protein EgHBX4.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SNL1_YEAST
Sequence: MSHNAMEHWKSKLSKTSTSTYVLLAVIAVVFLVTIRRPNGSKGKSSKKRASKKNKKGKNQFEKAPVPLTLEEQIDNVSLRYGNELEGRSKDLINRFDVEDEKDIYERNYCNEMLLKLLIELDSIDLINVDESLRRPLKEKRKGVIKEIQAMLKSLDSLK
What is the function of this protein?
Stimulator of ATPase activity of molecular chaperones of the HSP70 family (principally of the SSA class).  Stimulation is important for HSP70-substrate complex dissociation after folding of newly synthesized or refolded proteins.  SNL1 is probably involved in nuclear pore biogenesis and in particular the folding or refolding of misfolded NUP116, GLE2 and NIC96.
What are the official names of this protein?
HSP70 co-chaperone SNL1, Suppressor of NUP116-C lethal.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus membrane; Single-pass type II membrane protein.
Protein: ISPE_RHOP2
Sequence: MPTTALSDQARAKVNLTLRVVGRRVDGYHDLESVVAFADCADRLTLHPGAELSLVTSGPGAQDCGDTADNLVLKATRLLAERVPKLRSGAFVLDKHLPVAAGIGGGSADAAAALRLLARANDLAADDPRVVEAARLTGADVPVCLPSRPCVMTGVGDTLTPLPLPRLPAVMVNPRVPVATKDVFKALGLRAGQLNVGIVDVLKSKGWPAVDASVADWIVAVRRGTNDLEAPALKVEPIVGDVLRALAALPGVRMSRMSGSGATCFALFASDEDTKAGAEVLRAAHPGWWIHAGSLS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RL28_STRA5
Sequence: MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTVLIDGKPKKVWVSARALKSGKVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TUSA_ECOLI
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA (PubMed:16387657).  Interacts with IscS and stimulates its cysteine desulfurase activity (PubMed:16387657, PubMed:23281480).  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation (PubMed:16387657).  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin (PubMed:23281480).  Seems to affect the stability of sigma-S, particularly during the logarithmic growth phase (PubMed:9555915).
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_SHEAM
Sequence: MSWDQVWIDINIATMDPSMNEAYGAITDAALAVKDGKIAWLGKRSDLPEFDVLATPVHRGHGGWLTPGLIDAHTHLVFAGNRANEFELRLQGASYEEIARAGGGIVSTVKACRDADEAELFDLARRRLNALAKEGVTTVEIKSGYGLDLDTELKLLRVARELGQHHHVDVVTTFLGAHAVPPEFKTLGEAGTDAYVDLVVNEMLPAVVAENLADAADVFCENIAFNLEQTERVLSAAKTLGLDIKLHAEQLSNLGGSELAARLGAKSVDHIEYLDEAGVKAIAQSGTCAVLLPGAFYFLRETKLPPIDLLRQYQVPMVLASDFNPGSSPICSTLLMLNMGCTLFRLTPEEALAGVTRNAARALGRDQRVGVLREGMEADFCLWRISTPAELAYSYGVNPLVDVVKGGRLIHQ
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX23A_AGEAP
Sequence: KKKCIAKDYGRCKWGGTPCCRGRGCICSIMGTNCECKPRLIMEGLGLA
What is the function of this protein?
Omega-agatoxins inhibit neuronal voltage-gated calcium channels.  This toxin acts by modifying the gating of the high voltage activated P-type Cav2. 1/CACNA1A channel.  Is a potent blocker in both insect and mammalian central neurons.
What are the official names of this protein?
Omega-agatoxin-Aa4a, Omega-AGTX-Aa4a, Omega-agatoxin IVA, Omega-Aga-IVA, Omega-agatoxin-4A.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family. 03 (omega-agtx) subfamily.
Protein: EX7L_CHLTB
Sequence: MSITSPPIEVSVLTDSIKNLLEKNFLRVVVKGELSNVSLQTSGHLYFAIKDSKAVLNGAFFHFRSKYFDRKPKDGDYVILHGKLTVYAPRGQYQIVAYALTFSGEGNLLQQFEERKQRLAAEGYFDPKRKKPLPSGARVIGVITSPTGAVIQDILRVLSRRCHQFQVILYPVTVQGATAAQEISQAIQFFNQNSMRVHALIIARGGGSIEDLWAFNEEELVKSIVASSIPIISAVGHETDFTLCDFASDVRAPTPSAAAEIVCKSSDQYRQELQNLRRYVSSHARQFIAAKKNLLTHWQRHLASVDFYHTAQQTLDYTRAALERGIETKLEYYKQRFAQYRRWLKSDVLIRIEKHLADLNQSLMLSIKNKIYTKKTSLNQLYTSCLKNELLNLQHRTQHSRNILSQLSRRLHIAIASSQQTHQECLVRLQNELSFTIQHLLTKAKERCQAIQEQASSLNPKNVLKRGFAQLFDFNKHFVIISAESLKQSDLVRVCLQDGEAVVSVKEVWLNNDKKG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_BURM9
Sequence: MTKKVYVKTFGCQMNEYDSDKMVDVLNAAEGLEKTDTPEDADIILFNTCSVREKAQEKVFSDLGRVRELKEAKPDLLIGVGGCVASQEGASIVARAPYVDLVFGPQTLHRLPQMIDARRESGRAQVDITFPEIEKFDHLPPARVEGPSAFVSIMEGCSKYCSYCVVPYTRGDEVSRPLDDVLTEVAGLADQGVREVTLLGQNVNAYRGAIAAGSAEIADFATLIEYVADIPGIERIRYTTSHPKEFTQRLLDVYAKVPKLVDHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPNLSLSTDIIVGFPGETDADFDKTMALVHEMSYDTSFSFIYSPRPGTPAANLADDTPRELKLKRLQHLQATIEENVARISQSMLGKVERILVEGPSRKDPNELAGRTENNRVVNFPAPSAAHPRLIGQMIDVKINHAYPHSLRGELVLAHGDASAATH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.