PharMolix/UniProtQA huggingface dataset:
Protein: WDR12_SALSA
Sequence: MSQLQTRFFTDNKKYSVDDVPFSIPAASEVQELSNVINKLLEAKNGSRSQIEFDFLVQGQFLRTSLSNHMEAEGISTEDVVEIEYVERFTAPQPEECMMHDDWISSVEADSEWILTGSYDKTAKIWSLEGKAVMTVAGHTDVVKDVAWVKRDGLTSLLLTASLDQTILLWEWNSERNKLKARHCCRGHAGSVDTIATDPTRTKFCSGSWDKMLKIWSAVATEEEEEEEEPPSRPRKKQKTEQLGLTRTPLMTLSGHNEAVSSVLWLDSEEICSASWDHTIRLWDAETGSVKTSLTGSKVFNHISYSPLCRRLASGSTDRHVRLWDPRSKDGSLVLLSLTSHSGWVTAVKWAPSHEHQLVSGSLDNLVKLWDTRSCKAPLYDVSAHEDKVLCVDWTDSRLMLSGGADNKLYTYRYTACETDAGA
What is the function of this protein?
Component of the PeBoW complex, which is required for maturation of 28S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein wdr12, WD repeat-containing protein 12.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: RS2_CLOK1
Sequence: MSIISMKQLLESGVHFGHQTRRWNPKMASYIFTERNGIYIIDLQKTVRKIEEAYEFVKKIASEGKDILFIGTKKQAQEAIKEEAKRSNMHYVNNRWLGGMLTNFLTIRNRIGKLEELEKMEEDGTFEVLSKKEVIKLRNEKQKLERNLGGIKAMNAENVGALFVVDPRKEKNAISEAKILGIPVVAIVDTNCDPDEVDYVIPGNDDAIRAVKLITSKVADAVIEGRQGEQLAEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: M1_I73A5
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVATTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRAIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: SFSA_HALH5
Sequence: MFLPFNTRLHHATFLRRPNRFIVEARLDTGEEVVAHLPDPGRLKELLLPEASIWLRHVDNPSRKTQWSVVCSQAPEGDVLVSLDTTLPNQLVTKALQQQEFLPLCQWAYVRQEFTYGGSRWDVLLREGEKQLLLEIKSVTLSEAGVAYFPDAVTARGTKHVKELTAIQQSGDYETAILLLAQREDVTEIRPAYHIDPHFSAALQEAEKCGVRLLGHTSKVTLEGIELGKPVKVDTSERKETSD
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: LEPA_PROM1
Sequence: MTNVPISRLRNFCIIAHIDHGKSTLADRLLQDTGTVSSRDMQEQFLDNMDLERERGITIKLQAARMNYKADDGEEYVLNLIDTPGHVDFSYEVSRSLQACEGALLVVDASQGVEAQTLANVYLALENDLEIIPVLNKVDLPGADPEKIKNEIESIIGLDTSKAISCSAKTGVGIPEILQAVVDRIPSPKDNTDQATKALIFDSYYDPYRGVIVYFRIMSGGISKKDKVLLMSSKKSYELDEIGVMAPDQVKVNSLHAGEVGYLAASIKAVADARVGDTITLVDRPAEDALPGYAEAKPMVFCGLFPTDADQYPDLRDALDKLQLSDAALKYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYDLDLIVTAPSVIYKVKMIDGEVKMIDNPATLPDPQKRETIEEPYVRMEIYAPNDYNGTLMGLCQDRRGDFIDMKYITTDRVTLIYEIPLAEVVTDFFDQMKSRTKGYASMEYHLIGYRENDLVRLDVLINSERADPLTTIVHKDNAYGVGKGLVEKLKELIPKQQFKIPLQASIGSRIIASEGISALRKDVLSKCYGGDISRKKKLLKKQAKGKKRMKSMGKVDVPQEAFMAVLKLNND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS2_HERAR
Sequence: MSVTMREMLEAGVHFGHQTRFWNPKMAPYIFGHRNRIHIVNLEKTLGMYQEAMKYIKQLSSNRGTVLFVGTKRQARETIAAEAARAGMPYVDQRWLGGMLTNFKTIKTSIKRLKELEALVEDGSMEKLSKKEALMFEREKIKLEKSIGGIKDMGGIPDAIFVVDVGYHKGAITEAAKLGIPVIGVVDTNHSPEGVAYIIPGNDDSSKAIMLYARGVADAILEGRASATNDLVESIKGGDDFVEVNEQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: XERS_STRPD
Sequence: MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTKVPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQKLFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_STRPD
Sequence: MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQIYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSVMDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVDMFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDILDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAITQEITEIVAGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UCP1_SUNMU
Sequence: MVASAEADVPPPTMLVKIASAGLSACLADIITFPLDTAKVRLQVQGERPNAPGVKYKGVLGTIATVAKTEGPLKLYGGLPAGIQRQISFASLRIGLYDTVQEYFNAHRKTPATLGNKISAGLMTGCVTVFIGQPTEVAKVRMQAQSSLHWLKPRYSGTYNAYYVIVKTEGFLGLWKGTSLNLTRNVIINCTELVVYDVLKEALVKNNVLADDIPCHLLAALTAGFCTTALASPVDVVKTRFINSPPGYYPHVHNCALNMLQKEGLRAFFKGFVPSFLRLGSWTVIMHVTFEQLKKELMKSRQTVDCAT
What is the function of this protein?
Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance.  Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane.  However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs.  Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP.  Regulates the production of reactive oxygen species/ROS by mitochondria.
What are the official names of this protein?
Mitochondrial brown fat uncoupling protein 1, UCP 1, Solute carrier family 25 member 7, Thermogenin.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TJB22_HUMAN
Sequence: NTGELFFGEGSRLTVL
What is the function of this protein?
J region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta joining 2-2.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RS11_MYCGI
Sequence: MAQAKKGAPKKGQKTRRREKKNVPHGAAHIKSTFNNTIVSITDPQGNVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAQEHGVKKVDVFVKGPGSGRETAIRSLQAAGLEVGAIADVTPQPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CLPP_YERPN
Sequence: MSYSGERDQFAPNMALVPMVVEQTSRGERSYDIFSRLLKERIIFLTGQVEDHMANLITAQMLFLEAENPEKDIFLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQACSMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGFQGQATDIEIHAKEILKVKSRMNELMAYHTGKSLEEIERDTERDRFLSAEQSVEYGLVDSVFTRRD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_BACC7
Sequence: MSHLLTMSELSEVEISEILKDAEDFANGKESKTTEQTFVANLFFENSTRTRFSFEVAEKRLGLDVLNFSADASSVQKGETLYDTIRTLESIGTKAVVIRHEQDRYFDELKDQVNIPILNAGDGCGNHPTQCLLDLLTIKQEFGRFEGLKIAIVGDVRHSRVARSNAEALTKLGATIYFASPEEWKDEDNTFGTYKPLDELVPEVDVMMLLRVQHERHDHYETDIMKEYHEKHGLTVEREKRMKEGSIIMHPAPVNRDVEIASELVECERSRIFKQMENGVYVRMAVLKRALPNVLGGMKHELFV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TRHO_BARBK
Sequence: MEKKFKVAALYCFADLKHYQKLQKPLLDLCQENGIKGTLLLAKEGINGTVAGSCAAIETLVRFITAEPAFQTPELKYSWASKMPFHRIKVRLKKEIVTMGVEGINPLKAVGTYVAPEDWNALIQDEETLVVDTRNDYEYMLGSFQGAVDPNIKTFREFPQWVANHQDELKKKKRIAMFCTGGIRCEKSTSYMRELGYEEVYHLKGGILQYLETIPKEESLWQGECFVFDERVSVRHGLEESGRELCRACRYPLGAEGKLSSHYEEGVSCDACYDTRSEFDKQRFRERHRQFQLAKARTMNSHQGL
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: MUTS_ECO24
Sequence: MNENIDKDFSSHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEEISPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RS15_BIFLO
Sequence: MALTAEEKQEIIAKYATHEGDTGSPEVQVALLSKRIADLTEHLKEHKHDHHSRRGMQLMIGDRRRLLDYLKRVDINRYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y100_STAAM
Sequence: MKRLNKLVLYISFLILVISFTAGCGMGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRDDQFDKNDKGTWIINSEMVVQPKGERMKSKGMVLYMNRNTKTTTGKYIVSETLHDEDGRPKSKDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYGSFKDLSKYKDGDISYNPEVPSYSAKYQLTNDDYNVKQLRKRYKIPTNKAPKLLLKGSGDLKGSSVGYKDIEFTFVEKKGENTFFTDSLHLEPSEDK
What are the official names of this protein?
Uncharacterized lipoprotein SAV0100.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RSMH_CARHZ
Sequence: MEFSHVPVLLNETIEHLNLKAGGVYVDATLGGGGHSEEILKRADCRVVGLDQDEDALNHAAKRLAPFGDRFIPVKSNFRNIRKVVYRLGLDAVDGVLMDLGVSSFQLDNPLKGFSFQHDGPLDMRMDPQNPKTAADVVNTYPEKELIRIFYEYGEERYAPQIARAIVKRREKKPFTSTLELAEEIIRAVPAKARREKHPAKRVFQAIRIEVNDELSSLEEGLVGAVEVLKPGGRIVVITFHSLEDRLVKNFFRREENPCICPKDFPMCVCGKKPRLKVITKKPLVPSEEEIEKNRRAHSAKLRAAEKLSFA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAKG1_MOUSE
Sequence: MESVAAESSPALENEHFQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLQELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGGEKKP
What is the function of this protein?
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.  In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.  AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.  Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.  Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits.  ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit.  ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive (By similarity).
What are the official names of this protein?
5'-AMP-activated protein kinase subunit gamma-1, AMPK gamma1, AMPK subunit gamma-1, AMPKg.
What is the protein family that this protein belongs to?
Belongs to the 5'-AMP-activated protein kinase gamma subunit family.
Protein: PERR_BACSU
Sequence: MAAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPNMSVATVYNNLRVFRESGLVKELTYGDASSRFDFVTSDHYHAICENCGKIVDFHYPGLDEVEQLAAHVTGFKVSHHRLEIYGVCQECSKKENH
What is the function of this protein?
Hydrogen and organic peroxide sensor.  Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA.
What are the official names of this protein?
Peroxide operon regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP58_ARATH
Sequence: MSFFPPQQQQTPQPLFQTQQTSLFQPQQTNSIFSQSQPQQTNSIFSQSQPQQTNSIFSQPQQQQQTSLFQPQQFQQQQQQLNQQQQQQVQQQLYLFTNDKAPANYSTKWADLHPDSQKLLLQIEEKILEHRSESQRLDQCSRLYDSSVSSEGFEFDASRIVQELGGINTAMDRQKAVLHELMIVAKDMLRNAEIAVRSFMMLQPRFPHWKQGGGVVSVGSQPSQGQGTNPAPASSGQQQAVTTTVQVSDFYRGIPKKPTAFLLQTVVRFEKYLNECRQWVEELEQLLALDSDKYSRHASLLESLPKVMSNVHDFFVHVAAKVESIHQYIESMRTSYLADQRRRGECHDPFLEADRRETAKQEAAAKRVHPTLHLPASTTSTQPSTQVAGLIASSATPGGSNPPQTSVPTSNPSSGAGFSFLNTPASGPSSSLFATPSSTAPTSSLFGPSPTPTQTPLFGSSPASTFGSTQSLFGQTTPSLTMPSQFGGATPGSGASFGSMTKSSRPKSRTTRR
What is the function of this protein?
Involved in nucleocytoplasmic trafficking.  May have regulatory roles in the gibberellin pathway, in auxin signaling and in light perception.
What are the official names of this protein?
Nuclear pore complex protein NUP58, Nucleoporin 58, Protein TRANSCURVATA1.
What is the protein family that this protein belongs to?
Belongs to the NUP58 family.
What are the subcellular locations of this protein?
Nucleus envelope. Nucleus, nuclear pore complex.
Protein: RL16_NITWN
Sequence: MMQPKKTKFRKAHKGRIHGVASSGATLAFGQFGLKAMAPERITARQIEAARRALTRHMKRAGRVWIRVFPDVPVSKKPAEVRMGSGKGAPELWVVRVKPGRVLFEIDGVAPQTAKEALTLAAAKLPIKTRFVARIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CBDC_BURCE
Sequence: MLHSIALRFEDDVTYFITSSEHETVADAAYQHGIRIPLDCRNGVCGTCKGFCEHGEYDGGDYIEDALSADEAREGFVLPCQMQARTDCVVRILASSSACQVKKSTMTGQMTEIDRGSSSTLQFTLAIDPSSKVDFLPGQYAQLRIPGTTESRAYSYSSMPGSSHVTFLVRDVPNGKMSGYLRNQATITETFTFDGPYGAFYLREPVRPILMLAGGTGLAPFLSMLQYMAGLQRNDLPSVRLVYGVNRDDDLVGLDKLDELATQLSGFSYITTVVDKDSAQLRRGYVTQQITNDDMNGGDVDIYVCGPPPMVEAVRSWLAAEKLNPVNFYFEKFAPTVGN
What is the function of this protein?
Electron transfer component of 2-halobenzoate 1,2-dioxygenase system.
What are the official names of this protein?
2-halobenzoate 1,2-dioxygenase electron transfer component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: PARC_RICPR
Sequence: MKEAKIENIDFGNALSERYLAYALSTIMSRSLPDVRDGLKPVHRRLLYAMLQLRLEPNSGYKKCARVVGDVIGKYHPHGDVAVYDTLVRLAQHFSLRYPLIDGQGNFGSIDGDNAAAMRYTESRMTEICMLLMEDIDKDTVDFRSTYDDSDLEPVIMPASFPNLLANGSEGIAVGMATNIPPHNLHELCDALLYLIDNPQAGINDIMNFIKGPDFPTGGIIIDKAEVINAAYTTGRGSFRVRSRWEKEELSYGTYQIVVTEIPYQIQKSKLIEQIAILLKDKKIPLISSIRDESTDIIRVVIEPRDRSCDPQIVMESLFKLTNLESRIQLNMNVIGSNNVPRVMNILEILQEFLVHRKNIIIRRSTYLLNKIKQRLEILKVLRIVYLNLDEIIEIIREEDEPKTIIMERFKISAIQVEVILNTRLRSLQKLEEHAIIDEHSNLQKQQAILEKILKNHKELWQIVKKEIKAVQTKFGLNTIIGARRTSFEEVDLTNQVVDITAFITKEPITIICSKMGWVRSLKGHNTDLSTIKYKEGDTEKFIIEAYTTDKILIISSKGRFFTLLADNISKGKGTGGVSIKLLVDIGNNDITNILVYKPNQLLLLASSIGKGFLVNSNEVIAQTKTGKQIMNIPEGYSCIACLPVNGDSIACIGESRRLLVFNIDEIPEMKKGQGVVLQRFKNAKLLDIKIFNKQDGLSWNDGTKIQLEKNIVAFLGKRGGFGTFPPIGFPKNNRFSP
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL20_STRPG
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVADAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: OFOA2_SULTO
Sequence: MTRIVWMIGGAQGLGVDTSANIFGNAVAKAGYYLFGNREYYSNIKGRHSYFEVVISEKPIRSLSSYVNILASFDAETVFQHFTETKEYLIYNVEYENTTVDLVKSMEPEMAEQVKEALSKERLGFTIKDVLEYLKRRGVKVIGFNYTELIKKIADTFKVPMSVVERAKNMIAVGASYGLLGLKFDYLKDAISSTFKNELFIKFNTMAAELGYNSVPNVYKLQEYKIEKQRIQVDGNTISAMGKLAGGLRFQSYYPITPASDESVYIEANQNLDMIVEGNELRKGGVVVVQAEDELAAINMAVGAALTGVRSATATSGPGFSLMSEGISWAGMNEVPVVITYYMRGAPATGLPTRSGQADLKFALNVGHGEFPRIVIASGDHVEIFWDAIWALNLAEKYQTPVIHIIEKTLANAYSVFEEELITNRPYVIERGKIVKPTSDYFNRFEVTEDGISPRVFLGQASIFYTGDEHNEEGHITENSINRMKMYEKRNKKLETADKEIPEEQRVNIVGDADIVLLTWGSPKGAILDAMEELSKDGIKTMMVQVKMFNPYPKNLMKKILSGKSKIIAVENNYNAQGAEVLAEKTGIFATNYILKWTGRPITREEVIEGIKKILERDEKRVVLYGGA
What is the function of this protein?
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
What are the official names of this protein?
2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha, OFOR2.
Protein: MNTR_GEOSW
Sequence: MPTPSMEDYIEQIYILIEEKGYARVSDIAEALSVHPSSVTKMVQKLDKDEYLVYEKYRGLVLTAKGKKIGKRLVYRHELLEQFMRIIGVDEENIYHDVEGIEHHLSWNAIDRIGDLVQYFQEDPKRIETLRNIQKRNEQAEE
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPCR_HUMAN
Sequence: MLTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVGIFLCTGGRRC
What is the function of this protein?
Binds activated protein C.  Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
What are the official names of this protein?
Endothelial protein C receptor, Activated protein C receptor, APC receptor, Endothelial cell protein C receptor.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.