PharMolix/UniProtQA huggingface dataset:
Protein: HBA_BOVIN
Sequence: MVLSAADKGNVKAAWGKVGGHAAEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGAKVAAALTKAVEHLDDLPGALSELSDLHAHKLRVDPVNFKLLSHSLLVTLASHLPSDFTPAVHASLDKFLANVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS8_ALCBS
Sequence: MSMQDTLADMFTRIRNAQMAKKVQVEIPASKAKEAVAKVLKDEGYIAGYEVTGDKKPVMTVELKYYEGSPVIEKIARVSRPGLRVYKSAGEIPKVKDGLGVMIVSTNQGIISDRAARKANIGGELICEVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: URED_SPOPA
Sequence: MEFQYRGNKTVLSNCYQNPPLRASRPLYINPANRSEATVYLVETSGGIVEGDHNVFDIDIKEGADVCLIPQSATKIYPSYNGIWSSQDMDITIGPKASLSFKTEAVIPFEQARFNSKTVIQMTSDSTFLWGDILSPGRVARGEVFEYTDVRTNFQVWMDDECLIYDPLLISKDNMGLKKMGMLEDHLFIGSMWFVTPTIEEFDIRELNERLQESPHSKASASMLEGKAVNVRWLASDLVDLKKEMNRIWDEFANYIV
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMCB_CHLMU
Sequence: MNKLIRRAVTIFAVTSVASLFASGVLETSMAESLSTNVISLADTKAKETTSHQKDRKARKNHQNRTSVVRKEVTAVRDTKAVEPRQDSCFGKMYTVKVNDDRNVEIVQSVPEYATVGSPYPIEITAIGKRDCVDVIITQQLPCEAEFVSSDPATTPTADGKLVWKIDRLGQGEKSKITVWVKPLKEGCCFTAATVCACPEIRSVTKCGQPAICVKQEGPESACLRCPVTYRINVVNQGTATARNVVVENPVPDGYAHASGQRVLTYTLGDMQPGEQRTITVEFCPLKRGRVTNIATVSYCGGHKNTASVTTVINEPCVQVNIEGADWSYVCKPVEYVISVSNPGDLVLRDVVIEDTLSPGITVVEAAGAQISCNKLVWTLKELNPGESLQYKVLVRAQTPGQFTNNVVVKSCSDCGICTSCAEATTYWKGVAATHMCVVDTCDPICVGENTVYRICVTNRGSAEDTNVSLILKFSKELQPISFSGPTKGTITGNTVVFDSLPRLGSKETVEFSVTLKAVSAGDARGEAILSSDTLTVPVSDTENTHIY
What is the function of this protein?
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin.  It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan.  It is present but the disulfide bonds are reduced in reticulate bodies (RBs) (By similarity).
What are the official names of this protein?
Large cysteine-rich periplasmic protein OmcB, Large-CRP, 60 kDa CRP, 60 kDa outer membrane protein, Cysteine-rich outer membrane protein.
What are the subcellular locations of this protein?
Periplasm.
Protein: AMT1_CANGA
Sequence: MVVINGVKYACDSCIKSHKAAQCEHNDRPLKILKPRGRPPTTCDHCKDMRKTKNVNPSGSCNCSKLEKIRQEKGITIEEDMLMSGNMDMCLCVRGEPCRCHARRKRTQKSNKKDNLSINSPTNNSPSPALSVNIGGMVVANDDILKSLGPIQNVDLTAPLDFPPNGIDNKPMESFYTQTSKSDAVDSLEFDHLMNMQMRNDNSLSFPMSANQNEVGYQFNNEGNNSMNSTMKNTITQMDQGNSHSMTLHDIDEILNNGIELGNVN
What is the function of this protein?
Trans-acting regulatory protein that activates transcription of the MT genes (metallothionein) in response to copper or silver ions.
What are the official names of this protein?
Metal-activated transcriptional activator protein AMT1.
What are the subcellular locations of this protein?
Nucleus.
Protein: IHFA_RHILO
Sequence: MGGKTLTRADLAEAVYRKVGLSRTESAELVEAVLDEICEAIVRGETVKLSSFATFHVRSKNERIGRNPKTGEEVPILPRRVMTFKSSNVLKNRILRSHQNSKAKGGK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ACPS_ZYMMO
Sequence: MIIGIGTDLCNIDRITTILGKKESGRFIKRLFSCEEIEASSAFSMTKAAFFAKRFAAKEAFVKALGTGFRHSISFQDISISNDSLGAPKVNISGKAALLLEEKKPPRHTLSIHLSLSDDHPWALAFVVIEACPE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_DESHY
Sequence: MAKHRSNRLAETLKQEISQLIREELKDPRIGFVTVTSVEVADDLGNAKVYVSVLGDSQQAKDSLDALKRAAGFVRSEIGKRVRLRHAPEIVFKYDTSIEHGAHIAQLLRGVKQEEEKDEGESHDQ
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK14_RABIT
Sequence: MCDLIEPQPAEKIGKMKKLRRTLSESFSRIVLNVISFVFQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFKSSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPENVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPESGESMRAFGKNSSYGKSLSNSKH
What is the function of this protein?
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin.  Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway.  Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3.  Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo.  May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 14, Cell division protein kinase 14.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Note=Recruited to the cell membrane by CCNY.
Protein: UCAL_HORSE
Sequence: MNLLLLAMGLILPRRPHALHMGPGDPNFDEKLVKGKWFSVALASNEPKFIAKDTDMKFFIHKIQVTPESLQFHFHRKVRGMCVPTMMTAHKTKKKFQYTVNHSGHKTIFLEKVDPKHFVIFCAHSMKHGKETVVVTLFSRTPTVSPDVMWMFKKYCKTHGIHTSNIVDLTQTDRCLHARH
What is the function of this protein?
Binds fatty acids and retinol.  Is specialized for the preattachment embryo.  May be important to maintain the pregnancy and may transport small hydrophobic ligands from mother to the developing embryo.
What are the official names of this protein?
Uterocalin, Concepticalin, Equicalin, Lipocalin P19.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
Protein: METK_THEP1
Sequence: MRRLFTSESVTEGHPDKIADQISDAILDAMLEQDPRSRVAVETLVTTGLVIIAGEVTTRAYVEIPDIARKTILEIGYTRAKYGFDGETCGVLTSIHSQSPDIALGVDKALEVKTGEEVADEFEALGAGDQGIMFGYATNETPEYMPLPITLAHKLAMRLAEVRKNGTLPFLRPDGKTQVTIEYEDDKPVRVDTVLISTQHDPDISQADLREAIIEHVINPVIPEQYRDDKMKILVNPTGRFVLGGPMADTGLTGRKIIVDTYGGWVPHGGGAFSGKDPTKVDRSAHYMARYVAKNVVAAGLADKFLIQLSYAIGVAKPVSIMIDTYGTAKVDEDKLLKVITELFDFRPGAIIKKLNLLRPIYRKTAAYGHFGRNEEEFTWEKLDMVDELKRAFNM
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTD_PSEPW
Sequence: MTTHYIAGSWQAGQGEALQSLNPVTQAVVWQGQGADASQVDAAVLAARQAFPAWAQLSLEARIDVLEKFAEQLKQHSEALAYCIGEETGKPLWESATEVTSMVNKVAISIQSYRERTGEKSGPLADATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNCVVFKPSELTPKVAELTVNCWIAAGLPAGVLNLVQGARETGVALAANPGIDGLFFTGSSRTGNLLHQQFAGRPDKILALEMGGNNPLVVDGVKDLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDALVIRLVEVCKSITVGAFDQQPAPFMGSVISLQAARALVAAQSELLAKGATQLLEMTQPQADAALLTPGIIDVTAVADRPDEEFFGPLLQVIRYADFDAAIDEANNTQYGLAAGLLSDSRARYQYFWLRSRAGIVNWNKQLTGAASSAPFGGIGASGNHRASAYYAADYCAYPVASLETASLALPATLTPGVTL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: CLPX_XANP2
Sequence: MSKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGIPTPKEIRKVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDKIISSRSKGSTSIGFQAKVAPPEDRRPGEVFREVEPEDLLKYGLIPEFIGRLPVLATLGDLDEEALKKILSEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKAIERKTGARGLRSIMESILLDTMFDLPGLEGVEEVVISREVVEQSARPLYIYADRVGDAGASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: LPLT_ECO8A
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMIGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAK_DICNV
Sequence: MGKIIGIDLGTTNSCVAVMDGDSAKVIENSEGTRTTPSIIAFSDGEVLVGQPAKRQAVTNPKNTLYAIKRLIGRRFDEKEVQKDINLVPYNIVKSDNGDAWVEIDGKKMAPPEISARILQKMKKTVEDYLGETITEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAYGIDRGAKDAKIAVYDLGGGTFDISIIETIDLDEEGQQFEVLATNGDTFLGGEDFDRRIIDYLVNEFKKEQGIDLTSDSLALQRLKEAAEKAKIELSSSQQTDINLPYITADASGPKHMNLKLTRAKLESLVADLIERSLEPCRIAMKDAGLSNSDITDVILVGGQTRMPKVQEAVKNFFGKEPRKDVNPDEAVAMGAAIQGGVLGGQVKDVLLLDVTPLSLGIETLGGVMTKLIEKNTTIPTKASQIFSTAEDNQSAVTIHILQGERQQASANKSLGRFDLSDIPPAPRGMPQIEVSFDIDANGILNVSAKDKQTGKEQSIIIKASSGLSDEEVARMVKDAEAHAEEDRKFQERIETKNSAESMINGVEKAISELGDEVTSDEKEKTEAAIKALREVMKGEDSDAIKEKTNALMEAASSIMQKAYAKMTEKQQSDDGAGTQNADHKEDDVVDADFEEVKSDKKD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MURA_BRADU
Sequence: MAPIQYIVEGGHRLSGSIEPSGNKNSALPIIAAALLTEHPVTLENVPRIRDTETLVELIRSVGAAAEWTARNTLHIHAKSIRAADLDPELCVRIRASILLAGPLLARCGEVMLPPPGGDVIGRRRLDTHVLALEQLGAKVTATDRLEFRAPKLAGADVFLDEPSVTATENALVAAVAADGVTYLRNAASEPHVQDLANFLVALGAKIEGIGTNTMIIHGPATLGEATYRIQPDHIEVGSLIGLAAVTRSPLRIVRAGVEHLRSIRMGFERLGIVCRVEGDDLIVPSNQTLKIQDDFGGHVPKLEDQPWPAFPADLMSIAIVTATQCEGVILMFEKMFESRMFFVDKLIAMGARIVLCDPHRAIIAGPSRLRGAPMTSPDIRAGMAMLLAAVCAEGTSTINNADQIERGYERIEERLNALGAKIKRVPERKS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLK4_CAEEL
Sequence: MQQNIRIQKNQYDTATHPTASSTTWKYVTYDETSETFGMSEQVADPCNHCPKPRNYNSECKDEDVEKHFEKVMPCVHTYTIIYGNVHHLPNHPIIRNLRHNHY
What are the official names of this protein?
Uncharacterized protein D1044.4.
Protein: HYALP_CAVPO
Sequence: MGAFTFKHSFFGSFVECSGVLQTVFIFLLIPCCLADKRAPPLIPNVPLLWVWNAPTEFCIGGTNQPLDMSFFSIVGTPRKNITGQSITLYYVDRLGYYPYIDPHTGAIVHGGLPQLMNLQQHLRKSRQDILFYMPTDSVGLAVIDWEEWRPTWTRNWRPKDIYRNKSIELVKSQHPQYNHSYAVAVAKRDFERTGKAFMLETLKLGKSLRPSSLWGYYLFPDCYNTHFTKPNYDGHCPPIELQRNNDLQWLWNDSTALYPSVYLTSRVRSSQNGALYVRNRVHESIRVSKLMDDKNPLPIYVYIRLVFTDQTTTFLELDDLVHSVGEIVPLGVSGIIIWGSLSLTRSLVSCIGLENYMKGTLLPYLINVTLAAKMCGQVLCKNQGICTRKDWNTNTYLHLNATNFDIELQQNGKFVVHGKPSLEDLQEFSKNFHCSCYTNVACKDRLDVHNVRSVNVCTANNICIDAVLNFPSLDDDDEPPITDDTSQNQDSISDITSSAPPSSHILPKDLSWCLFLLSIFSQHWKYLL
What is the function of this protein?
Involved in sperm-egg adhesion.  Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida.  The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation.  This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
What are the official names of this protein?
Hyaluronidase PH-20, Hyal-PH20, Hyaluronoglucosaminidase PH-20, Sperm adhesion molecule 1, Sperm surface protein PH-20.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: YBAB_ECO57
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SJ766_SCHJA
Sequence: MKQFYSVVLTIIIYISSQSNVVSLDCRKLNEDCSKTVFSPCCDPLSCALSTAFNGKCKACLAGGYFCWRSDECCSGTCSWLKCTNPLTDIINKLTD
What are the official names of this protein?
Uncharacterized protein SJCHGC09766.
What are the subcellular locations of this protein?
Secreted.
Protein: AT1A1_HORSE
Sequence: MGKGGGRDKYEPAAISEHGNKKKAKKERDMDELKKEVSMDDHKLSLDELQRKYGTDLSRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVVRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVTFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLSLSRIAGLCNRAVFQANQENIPILKRAVAGDASESALLKCIELCCGSVKEMRDRYPKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLNGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPLENLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTPEQLDDILRHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWVNDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-1, Sodium pump subunit alpha-1, Na(+)/K(+) ATPase alpha-1 subunit.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection, axon. Melanosome.
Protein: RS6_THEPX
Sequence: MRSYETMYILSPDLSEEERKGLIERFKNLIIENGGEITNFDEWGKRKLAYLIDKKPEGYYVLMNFNSDSKVSQELERVYKITDGVLRYLIIRTDE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: HEMA_I79A0
Sequence: QNLPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDSPHRILDGKNCTLIDALLGDPHCDGFQNEKWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINEGFNWTGVTQSGGSYACKRGSDNSFFSRLNWLYESESKYPVLNVTMPNNGNFDKLYIWGVHHPSTDKEQTNLYVRASGRVTVSTKRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDILLINSNGNLIAPRGYFKIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPXQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMXXGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKXGYKDWILWISFAISCFLLCVVLLGFIMVXCQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: NQRD_VIBCH
Sequence: MSSAKELKKSVLAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTLAVMFVTALSNFFVSLIRNHIPNSVRIIVQMAIIASLVIVVDQILKAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSEPIPSFIDGIGNGLGYGFVLMTVGFFRELLGSGKLFGLEVLPLISNGGWYQPNGLMLLAPSAFFLIGFMIWAIRTFKPEQVEAKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF2_LIMRJ
Sequence: MAKERIYELAKELKMPSKDLVNMANRQGMGVKSHMSSVTPDQAQQLRQLAKGGQKTTNNQHQPVKKNDGHNKQNNHQAQNHNQHHDHDKTQNERPQKKNNSRSNNGTKDNNQHQNNGGRFGGSLNNDQGRNGKRFNKKNKKNKKHNKNKRLREVAHKQPTQRKDKPLPEVLEYTDGMNAQDLGKILHRSPAEIVKKLFMLGVMINQNQSLDKDTIELLATDYGIEAKEKVQVDVSDIDKMFEDEQNNTEHQVTRPAVVTVMGHVDHGKTTLLDKLRHSHVTEHEAGGITQEIGAYQVHYNDQLITFLDTPGHAAFTEMRARGANITDITVLVVAADDGVMPQTVEAIHHAQAAQTPIIVAVNKIDKPGANPDRVTEELAKYNLIPEDWGGDTIFVKISAKFGKNLDELLDMILLQAEMLELKANPDQNAAGSVVEARLDQGRGSVATVLVQQGTLHVGDPIVVGNTFGRVRTMTNENGRRIKEATPSTPVEITGLNEVPEAGDRFVVFDDEKTARAAGEERAKRAMDKERQKTSHVTLDNLFATMKKGQMKTLPIIIKADVQGSVEALSQSLQKIKVDGVRVDIIHQAVGAINQSDVTLAEASNAVIIGFNVRPTAVAKTLADSNSIDIRLHRVIYDAIEEVEDAMKGMLEPVYKEETIGQVEVRQIYKASKVGTIAGGMVTSGKITRDAKVRLVRDGVVIYEGELGSLKRFKDDVKEVKQGYECGLTIENYNDIKEMDVIEAYKMKEVPVK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTRAL_STAHJ
Sequence: MDNDKKHVIPREQYRRKRHEYFHNEEREERLEREREQRERLAKKEQEQAKVNEERVKDNMRKARIEKLTQEEIHQQQHLAKLRSDNESDQELNDTNTHHLTLPEEQQLKNEHKENNDKVTKPTDEMEKQEKEDNNSASSKHDEIEPKYSRVEKNKGKQKQDNINKSEVNHLDKSEQTKKHKETKESSEDVLETNKSQKIEQKEQKASSNETSNKELNSYTKDKNNKVEDNQDLKKASSQNLAHSNKLEENEHLENEPKNNDTMDKVKDFLKLHWLKIVIVVAIILIVILISAIISTMNQNSSIEQSSNNDTKYTTTMKNAETAVKSVVTIENDTPKNITTQTIDKTNINSNNEVGSGVVYKAVDDTFFILTNTHIVGSNKRVNITYDDDKTATATVVGRDMWSDIAVLKATIKNKNMQPIKIGHSKHLKLGESILVVGNPLGNDFKNTVTKGIISGLNRAVPVDFDKDNKNDEWVNTFQIDASVNPGNSGGAVVNRVGELVGLVSLKINMPNIEGMGFAIPIDAAREIAEELEKKGEIQYPNTGIGIKNVSDLMPYERNLLKVPEDVQNGIVVEKLKENGLGKKSGLKIGDVVVELDSKSIQNNLQYRQIIFNHRQDLKTLSAKIYREGKSQEIRIKLK
What are the official names of this protein?
Serine protease HtrA-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CBID_METVS
Sequence: MTIDFRTETTFGYTTGACAVSGAYSALYFLKNNKKLDFVEILNLKNETLIIPIQNIERSENTAFATVKKFSGKDIDITNNMTINVEVTLQKLDNNSNLKLIEIFGGNGVGIVTKRGLQIDVGDYAINPKPREMIEKNLISLLNDGEKAVVRISIPNGDEISKKTLNPKLGIIGGISILGTTGIVRPMSNDAYKESLLPQIDIAIQNGFENLVFVPGNIGTKYAKSVLNIEEDQIIEVSNFWGFMLEKAGEKGVKDITVFGHAGKIVKLAGGIFDTHSKVSDARNEILCAYTSTLCNNQELMKKILQSNTTEEIIEILAEKDILNEVFNLISKRVVERLCLRFPNIKFSCIIVDINGKILGKCFLGDRFD
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.