PharMolix/UniProtQA huggingface dataset:
Protein: APPA_BACSU
Sequence: MKRRKTALMMLSVLMVLAIFLSACSGSKSSNSSAKKSAGKPQQGGDLVVGSIGEPTLFNSLYSTDDASTDIENMLYSFLTKTDEKLNVKLSLAESIKELDGGLAYDVKIKKGVKFHDGKELTADDVVFTYSVPLSKDYKGERGSTYEMLKSVEKKGDYEVLFKLKYKDGNFYNNALDSTAILPKHILGNVPIADLEENEFNRKKPIGSGPFKFKEWKQGQYIKLEANDDYFEGRPYLDTVTYKVIPDANAAVAQLQAGDINFFNVPATDYKTAEKFNNLKIVTDLALSYVYIGWNEKNELFKDKKVRQALTTALDRESIVSQVLDGDGEVAYIPESPLSWNYPKDIDVPKFEYNEKKAKQMLAEAGWKDTNGDGILDKDGKKFSFTLKTNQGNKVREDIAVVVQEQLKKIGIEVKTQIVEWSALVEQMNPPNWDFDAMVMGWSLSTFPDQYDIFHSSQIKKGLNYVWYKNAEADKLMKDAKSISDRKQYSKEYEQIYQKIAEDQPYTFLYYPNNHMAMPENLEGYKYHPKRDLYNIEKWWLAK
What is the function of this protein?
This protein is a component of an oligopeptide permease, a binding protein-dependent transport system.  This APP system can completely substitute for the OPP system in both sporulation and genetic competence.  AppA can bind and transport tetra- and pentapeptides but not tripeptides.
What are the official names of this protein?
Oligopeptide-binding protein AppA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: O22R_FRG3G
Sequence: MANATIKYTTMDLYGILKSCKCSSDERLTHQSLSGGRFSVTGSKVGEFWRAVADRIESGEPIDISEARQKETPLTLDFDVVDKDCKEPVPDVLVNNIHAAVARWARSSLKPAPEDRDLCGVVLTKPVRQCAKGWKKGFHIQYPKLVLETGVAKNLVVGPALRPICSKVWEAVTGTAKDYLDPLSCTVPWLVYGASKPDEPFAWKIARTLDHAGKTIDFNTAFGDVETPPSWGRPTSDRHREAMVLSIHPAGRSVFFRRYDFTAANPGRVTRLADYSAVMAKLDVARQRKPAWNTDATKAHRLKRVTDLTAMLTADLADDRQTWLNVGFCLWQQTSGSAEGYKVWLSFSKKSDKCDEDECWTIWNNQMRPNSFTEGTLVYLAQKHNPGAYLNWLQVKSTPVNDIGTNVAMAKIMWDYYGHQFVCCGGKTQTWYRFDGLTWVESNQGTDLRSLISAEGGPLRRLLMRQLDAVTAAKARGGRDSGNEDDEEDSATDEDDSNPWDSELRRLDSEVLDTMVKRLRNNLKGIEMTGVKNNVLRECAELFYQPEFGDVIDSDPLLFAFANGIYDFREGCLRDGRPEDKLSRRAPVDFVMFGPIPKARHPDNSPVMRPKRMPGESVQDHARRLAECFEQDDVSASAGTMGKEDVESFSCNPNDFKGPVTKLLAFFASVFPDEGTRRFFLRNAAATFVGGNPDKVVLFWTGTGNNGKTVTQTLFEKMLGCFAVKMSTQTLTGRKPSAGSANPEMARLGGGVRWAVMEEPNSDETINAGTLKSMTGNDSFFARDLYCAGKTTFEIKPMFKLHVICNALPGIKDADQATWNRVRVVPFESTFVTPGTTAPADAKYVFPADTDITRKLDRLTAPLAWYLVYCWACIQNERVKYVPPPKVMEATMAYQKEHDLFRQFVEEMLRKDPDSTLTCDDAYTAFRDWTSANSPHGTVRRPKGQVVKCLEAILGKKTVDGWPGYAVGAEQQE
What are the official names of this protein?
Putative helicase 022R.
Protein: TSAC_XANAC
Sequence: MTDTLDLDRAVAALTQGGVIAYPTEAVWGLGCDPRQRAAVMRLLEIKRRPVEKGVIVVASSVDVLRDWVDIDALEPARRRDVLTSWPGPHTWILPITDRAPRWVTGEHDGLAVRISAHPVVAALCGAWGAPLVSTSANLAGEPPARSRAALDPALLATIDGVVDGETGALAQPTQIRDARSGQILRD
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_AZOVD
Sequence: MQAYQREFIRFAIERGVLRFGEFTLKSGRTSPYFFNAGLFDSGLALARLGRFYASALVGSGIAFDVLFGPAYKGIPLAAATAVALAEHHGLDLPWCFNRKEAKDHGEGGSLVGAPLSGRVLIVDDVITAGTAIREVMQIIQGQGARAAGVLIALNRQERGQGALSAIQEVERDFAMPVVSIASLSDVLEYLAEDAQLKRHLSAVEAYRAQYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: KAIB_PROM4
Sequence: MSPRKTYILKLYVAGNTPNSMRALKTLHEILENEFKGVYALKVIDILKSPQLAEEDKILATPTLTKILPPPVRRIIGDLSDRERVLIGLDLLYEELSGNEFLSSIASPNSDEDN
What is the function of this protein?
May be a metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, and perhaps clock output effectors.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: SYE_MARMS
Sequence: MSEVRTRIAPSPTGDPHVGTAYIALFNMAFARKMGGKFILRIEDTDQTRSTPESEKMILDALRWLGLDWAEGPDVGGPYGPYRQSERGDIYGQYAQELIDKGHAFYAFETTEELDQMRNEQKEQGLPQKYDGRALNLTAEEVQAKLDAGVPYVIRMKIPEEGTCVVQDMLRGTIEIDWAQVDMQVLLKADGMPTYHLANVVDDHLMKITHVIRGEEWINSAPKHILLYQYFGWDMPTLCHMPLLRNPDKSKLSKRKNPTSILYYQRMGYMSEAVINYLGRMGWSMPDEREKFSLDEMIEHFDIQRVSLGGPVFDVEKLSWLNGMWIRENLTPETFAQKYVEWALNPEYLMKILPLVIPRVETFSDVADVAGFFLKGMLPITKEDFSSIKLEEETLRKAMQFALWRLEALSKWEKDEIFNEMKALAQVMEIKPKDFFAPLFVAISGTTASVSVFDSMAILGSDISRARMRTAVNVLGGPSKKEAKRWEKEYADL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_BIFLO
Sequence: MALETKPAKDPAAEDKHELDPKRKAALDTALAQVEKSFGKGSAMRLGDQPEQNVEVIPTGSLALDMALGIGGLPKGRIVEIYGPESSGKTTLALHVVANAQKKGGVAAYIDAEHALDPAYARKLGVDTDSLIVSQPDNGEQALEIADMLIRSGALDVIVIDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKMTGALAQAGTTAIFINQLREKIGVFFGNPETTTGGKALKFYASVRLDIRRIQTLKNGDEAVGNRTRVKVVKNKMAPPFKSAEFDMLYGEGISREGSVIDMAQQVGVVKKSGSWFTYEGDQLGQGREKVRQFLKDNPAITEEIENKVKAEFGLIGSADQFAEDGEAAAAAAVSEAAAADVAKDSKAAAAPAAKTTRAKAGTAKA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_YERPS
Sequence: MGTTSSQSKTLYQKLYDAHIVHEAPNETPLLYIDRHLVHEVTSPQAFDGLRAMGRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLYDLNHPFQGIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAKTMRIEVNGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMAIEMGAKAGLVAPDDTTFAYLKGRQFAPTGEQWEQGVAYWRTLKSDADAQFDTIVTLDAADIAPQVTWGTNPGQVIAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDKVFIGSCTNSRIEDLRAAAAIAQGRKVAKGVQAIVVPGSGPVKAQAEAEGLDKIFIAAGFEWRLPGCSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSGHFADVRELSAATH
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: ECPC_ECO57
Sequence: MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQAFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASVSEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSEDIGQSSVNTLSSNLSYNFGIYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIGSGQQDSELYKAMYERDFAGHRFAGGTLDTWNLQSLGPMTAISAGKIYGLSWGNQASSTIFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEVIVNGRVISKRTQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLAGASTSGSLSTLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSSIGSISATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSNANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYVNTNLTANGSVGWQGKNIAASGRTDGNAGVIFNTGLEDDGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVIEPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYSGNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity).
What are the official names of this protein?
Probable outer membrane usher protein EcpC.
What is the protein family that this protein belongs to?
Belongs to the EcpC/MatD family.
Protein: Y8KD_STRLI
Sequence: MHHQDRDQDQALAAVLAALLLVGGTLIVRELLGLWPAVAVGMAPALALYGGPPAARRIAVAVEVRRFRRHLAHHDRAAG
What are the official names of this protein?
Uncharacterized 8.4 kDa protein, ORF 79.
Protein: PETH1_THEFY
Sequence: MPPHAARPGPAQNRRGRAMAVITPRRERSSLLSRALRFTAAAATALVTAVSLAAPAHAANPYERGPNPTDALLEARSGPFSVSEERASRFGADGFGGGTIYYPRENNTYGAVAISPGYTGTQASVAWLGERIASHGFVVITIDTNTTLDQPDSRARQLNAALDYMINDASSAVRSRIDSSRLAVMGHSMGGGGTLRLASQRPDLKAAIPLTPWHLNKNWSSVRVPTLIIGADLDTIAPVLTHARPFYNSLPTSISKAYLELDGATHFAPNIPNKIIGKYSVAWLKRFVDNDTRYTQFLCPGPRDGLFGEVEEYRSTCPF
What is the function of this protein?
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle (PubMed:18658138).  Shows esterase activity towards p-nitrophenol-linked aliphatic esters (pNP-aliphatic esters) (PubMed:18658138, PubMed:25545638).  Also hydrolyzes the triglyceride triolein (PubMed:18658138).  Capable of degrading the plastic poly(ethylene terephthalate) (PET), the most abundant polyester plastic in the world (PubMed:25545638).
What are the official names of this protein?
Cutinase, Poly(ethylene terephthalate) hydrolase, PET hydrolase, PETase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Secreted. Periplasm.
Protein: NU2C2_VITVI
Sequence: MIWHIQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVSFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYIRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YKUE_BACSU
Sequence: MKKMSRRQFLKGMFGALAAGALTAGGGYGYARYLEPHMIETTEHTIKSSLIPHGFDGFKIVQFSDAHLSDYFTLEDLKTVILTINESKPDLIVFTGDIIDNPDTYQHHQAVIPLLRKLNAPFGKLCIYGNHDHGGYGTAVYKSLMTAGGFTVYRNGYQTLSLADGSKIEIASLDDLMLGNPDYEGTLSRLSDRLFSILLVHEPDAALKTTDYPVNLQLSGHTHGGQIQLPFYGPIITPPYGKVYTEGMYQTGSTHIYVNRGLGMTRLPLRFLAKPEITVFTLKSTN
What are the official names of this protein?
Uncharacterized metallophosphoesterase YkuE.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily.
Protein: O11H1_HUMAN
Sequence: MCPLTLQVTGLMNVSEPNSSFAFVNEFILQGFSCEWTIQIFLFSLFTTTYALTITGNGAIAFVLWCDRRLHTPMYMFLGNFSFLEIWYVSSTVPKMLVNFLSEKKNISFAGCFLQFYFFFSLGTSECLLLTVMAFDQYLAICRPLLYPNIMTGHLYAKLVILCWVCGFLWFLIPIVLISQMPFCGPNIIDHVVCDPGPRFALDCVSAPRIQLFCYTLSSLVIFGNFLFIIGSYTLVLKAMLGMPSSTGRHKAFSTCGSHLAVVSLCYSSLMVMYVSPGLGHSTGMQKIETLFYAMVTPLFNPLIYSLQNKEIKAALRKVLGSSNII
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 11H1, Olfactory receptor OR22-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH1_HUMAN
Sequence: MSWLLFLAHRVALAALPCRRGSRGFGMFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVRKSASPEVSEGHENQHGQESEAKASKRLREPLDGDGHESAEPYAKHMKPSVEPAPPVSRDTFSYMGDFVVVYTDGCCSSNGRRRPRAGIGVYWGPGHPLNVGIRLPGRQTNQRAEIHAACKAIEQAKTQNINKLVLYTDSMFTINGITNWVQGWKKNGWKTSAGKEVINKEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSED
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed:10497183).  Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed:21700224).
What are the official names of this protein?
Ribonuclease H1, RNase H1, Ribonuclease H type II.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG145_MONPV
Sequence: MSLLKMEYNLYAELKKMTCGQTISLFNEDGDFVEVEPGSSFKFLIPKGFYSSPCVKTSLVFETLTTTDNKITSINPTNAPKLYPLQRKVVSEVVSNMRKMIELKRPLYITLHLACGFGKTITTCYLMTTHGRKTIICVPNKMLIHQWKTQVEAVGLEHKISIDGVSSLLKELKTQSPDVLIVVSRHLTNDAFCKYINKHYDLFILDESHTYNLMNNTAVTRFLAYYPPMMCYFLTATPRPANRIYCNSIINIAKLSDLKKTIYIVDSFFEPYSTDNIRNMVKRLDGPSNKYHIYTEKLLSVDEPRNQLILDTLVEEFKSGTINRILVITKLREHMVFFYKRLLDLFGAEVVFIGDAQNRRTPDMVKSIKELNRFIFVSTLFYSGTGLDIPSLDSLFICSAVINNMQIEQLLGRVCRETELLDRTVYVFPNTSIKEIKYMIGNFVQRIISLSVDKLGFKQESYQKHQESEPASVPTSSREERVLNRIFNSQNR
What is the function of this protein?
DNA helicase which seems to act as a postreplicative transcription termination factor.  Involved in ATP-dependent release of nascent RNA.  Forms a stable complex with single-stranded DNA, and to a lesser extent RNA.
What are the official names of this protein?
Transcript termination protein OPG145, 56 kDa abortive late protein.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Poxviruses subfamily.
Protein: RNC_STAA1
Sequence: MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAKSAYKQLKQIK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1MA5_LOXDE
Sequence: WIMGHMVNAIAQIDELVNLGANSIETDVSFDKNANPEYTYHGIPCDCGRTCTKSEKFNVFLQGLQKATTPGDSKYQEKLVLVVFDLKSSSLYDNQASDAGKKLAKSLLQNYWKNGNNGGRAYIVLSIPNLAHYKLITGFKETLKTEGHPELMEKVGYDFSGNDDIDQVAKAYKKAGVTGHVWQSDGITNCLPRGLDRVKQAVANRDSSNGFINKVYYWTVDKRSTTRGALDAGVDGIMTNYPDVIADVLSESAYKSKFRIATYEDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LdSicTox-alphaIB3av, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HELS_PYRAB
Sequence: MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLEDEYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLRIEGIGAKIVEGIFKYLGKEVKITERPRKGTLDYFLNP
What is the function of this protein?
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
What are the official names of this protein?
ATP-dependent DNA helicase Hel308.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Hel308 subfamily.
Protein: IGA0_HAEIN
Sequence: MLNKKFKLNFIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGRFSVGATNVEVRDKNNHSLGNVLPNGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKSHRDVSSEENRYFSVEKNEYPTKLNGKAVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYKVNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGYNKKSWQEWNIYKPEFAKTVLDKDTAGSLTGSNTQYNWNPTGKTSVISNGSESLNVDLFDSSQDTDSKKNNHGKSVTLRGSGTLTLNNNIDQGAGGLFFEGDYEVKGTSDSTTWKGAGVSVADGKTVTWKVHNPKSDRLAKIGKGTLIVEGKGENKGSLKVGDGTVILKQQADANNKVKAFSQVGIVSGRSTVVLNDDKQVDPNSIYFGFRGGRLDANGNNLTFEHIRNIDDGARLVNHNTSKTSTVTITGESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLYLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNGDLKVEKGTLFLSGRPTPHARDIAGISSTKKDQHFAENNEVVVEDDWINRNFKATNINVTNNATLYSGRNVANITSNITASDNAKVHIGYKAGDTVCVRSDYTGYVTCTTDKLSDKALNSFNATNVSGNVNLSGNANFVLGKANLFGTISGTGNSQVRLTENSHWHLTGDSNVNQLNLDKGHIHLNAQNDANKVTTYNTLTVNSLSGNGSFYYLTDLSNKQGDKVVVTKSATGNFTLQVADKTGEPTKNELTLFDASNATRNNLNVSLVGNTVDLGAWKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVETPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNGEVAEEAKPSVKANTQTNEVAQSGSETEETQTTEIKETAKVEKEEKAKVEKDEIQEAPQMASETSPKQAKPAPKEVSTDTKVEETQVQAQPQTQSTTVAAAEATSPNSKPAEETQPSEKTNAEPVTPVVSKNQTENTTDQPTEREKTAKVETEKTQEPPQVASQASPKQEQSETVQPQAVLESENVPTVNNAEEVQAQLQTQTSATVSTKQPAPENSINTGSATAITETAEKSDKPQTETAASTEDASQHKANTVADNSVANNSESSDPKSRRRRSISQPQETSAEETTAASTDETTIADNSKRSKPNRRSRRSVRSEPTVTNGSDRSTVALRDLTSTNTNAVISDAMAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSMNENYSSSQYRRFSSKSTQTQLGWDQTISNNVQLGGVFTYVRNSNNFDKASSKNTLAQVNFYSKYYADNHWYLGIDLGYGKFQSNLKTNHNAKFARHTAQFGLTAGKAFNLGNFGITPIVGVRYSYLSNANFALAKDRIKVNPISVKTAFAQVDLSYTYHLGEFSVTPILSARYDTNQGSGKINVNQYDFAYNVENQQQYNAGLKLKYHNVKLSLIGGLTKAKQAEKQKTAELKLSFSF
What is the function of this protein?
Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.
What are the official names of this protein?
Immunoglobulin A1 protease autotransporter.
What are the subcellular locations of this protein?
[Immunoglobulin A1 protease autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Immunoglobulin A1 protease]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Immunoglobulin A1 protease translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: UN07_CLOPA
Sequence: XXAKQSMDGNTAAA
What are the official names of this protein?
Unknown protein CP 7 from 2D-PAGE.
Protein: COQ7_XANOM
Sequence: MTQTSPSRLHSPLDRLLVEAQRALDTVFGNPPAERPNPAADTPDIALDPEQRRHAAGLMRINHVGEVCAQGLYFGQAAVARDAHTQHHLLEAAQEETDHLAWCADRLHELDSRPSLLNPLWYAGSYALGALAGLRGDDWSLGFVVETERQVEAHLDEHLETLPDIDQRSRAILRVMKIDEARHADQAEQAGARQLPAPIPGAMALASKLMKTVAYRL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: T4G1E_AGEOR
Sequence: MRTIISLLLLSAMVFAVIEAISLEEGLQLFEGERGCVGENQQCADWAGPHCCSGYYCTCRYFPKCICVNDNGK
What is the function of this protein?
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects.  Modifies presynaptic voltage-gated sodium channels (Nav), causing them to open at the normal resting potential of the nerve.  This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons (By similarity).
What are the official names of this protein?
U3-agatoxin-Ao1e, U3-AGTX-Ao1e, Mu-2Aga_06.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 03 (aga-4) subfamily. Aga sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7L_HERAR
Sequence: MPTDYPNPNQTPTSNVLTVSALNQAVSRMLERSFPLTWIAGEISNFTRAASGHWYFTLKDDAAQVRAVMFRGRAQYTDFMPREGDRVEVRALVTLYAPRGDYQLSVEAIRRAGVGNLYEAFLQLKEKLATEGLFDPARKRPLPLFARTIGIVTSPQAAALRDILTTLQRRAPHVRAILYPTPVQGEGAANKIAQAIATASARAECDVLLVCRGGGSIEDLWSFNHEIVARTIVGCDIPVIVGVGHETDFTIADFAADVRAPTPTAAAELAATPRTEWLARLQTEADDMRRALKRQLSDTAQTLDWLSRRLISPSATIAHKQMKLQNLQARLGHATRIPLGKAQFALAHLRNRWLTQLPDTRIQRARVAEHARRLSNQMKTRSATQEQRLRALSAQLEMLNPQRTLERGYAIVSDEKGHIVRAPQELRPRQNVTVRLAEGSAQIGIASVQQTLE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_OENOB
Sequence: MAIKSDQISSLIKQQLEKYDSTLKIDEVGTVTYVGDGVARASGLANVMSGELVEFENGVYGMAQNLEESEVGIIVLGDFDGISQGDTVKRTGKVMEVPVGDEMIGRVVNALGQPIDGNGAIKTKHTRPVEFKAPGVMQRKSVFEPLQTGIKVIDALVPIGRGQRELIIGDRKTGKTSLAIDTILNQKDQDMIVVYVAIGQKDSTVRTQVETLREMGALDYTIVVSAAPSEPAPMLYLAPYVGAALGEYFMYNGKHVLIVYDDLSKQATAYRELSLILRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLDADQFYSGNRPAIDAGTSVSRVGGDAQIKAMKKVSGTLRLDLASYHELEAFAQFGSDLDAPTQAKLARGRRTVEVLNQPLHQPMPVEHQVIVLYALTHGYLDDIDVSDIQRFQKELIDFVSGDKSYKKIFAAIKKTGNLPDEKDINSAIDDFKKHFSKSVEPTDYVAPSTKQEANK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.