PharMolix/UniProtQA huggingface dataset:
Protein: SYK_SODGM
Sequence: MSESHSQDGAPQALDMNNELRSRREKLGQLRQQGIAFPNDFRRDAVSDQLHARYGEKSNEELEALNIEVSIAGRMMTRRIMGKASFATLQDVGGKIQLYVARDDLPEGQYNEQFKKWDLGDILGTRGKLFKTRTGELSVHCSEIRLLTKAMRPLPDKFHGLADQETRYRQRYLDLIANDESRQTFKVRSRIMAEIRRFMMDNDFMEVETPMMQTIPGGAAARPFITHHNALGIDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGLSPRHNPEFTMMELYMAYADYRDLIVLVETLFRTLTQRVLGSSVVHNGDQTFDFGKPFTQMTMKEAICHYRPETRPEALDDMASATAIAESLGIKVDKSWGLGRVQTEVFEETAESHLIQPTFITAYPAEVSPLARRNDDNPFFTDRFEFFIGGREIGNGFSELNDAEDQAARFAEQAQAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRLMMLLTNSHTIRDVILFPALRPQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTC36_CAEBR
Sequence: MTTSHDRAVLNQILNPLMPTSDSGMGEVHLESDKVDHPGYTLSSQLEREAVRLAESMNVTDAIEKFTEAIQVCPLNPSAYNNRAQAYRLQNSPEKALEDLNESLRLAGPKTKTACQAYVQRASIYRLQGDDEKARADFAAAAELGSSFAKMQMVALNPYAAMCNKMLAEVFEKAKTGDN
What are the official names of this protein?
Tetratricopeptide repeat protein 36, TPR repeat protein 36.
What is the protein family that this protein belongs to?
Belongs to the TTC36 family.
Protein: SSTT_CHRSD
Sequence: MSATLASPLRALLRLGLIPQIVIGIALGVGVAIVWPDAATSVALLGQVFISALKAVAPILVFLLVMTAIANHRRGQPTHIRGVLLLYVVGTLCAALVAVLASFIFPTSLVIDAPQASGEPPGGIAEILRNLLLNVVDNPVNALLNANFVGILAWAMGLGMMLRGASETTLVVLNAFSDAVSSIVQLVIRCAPLGIFGLVAGTLADTGLNALLDYAHLLAVIVGCMLFVALVTNPLIVFLATRRNPYPLVFACLRGSAITAFFTRSSAANIPVNMELCKRLDLHPDTYSISIPLGATINMAGAAVTISVITLAATHTLGIGVDFATALLLCVVASLAACGVSGVAGGSLLLIPMAASLFGISPDVAMQVVAIGFVISVVQDATETALNSSTDVLFTAAACRARR
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C90A4_ORYSJ
Sequence: MAAAALLLLAAAAAAVVVAMALRWLLLLGGPAAGRLGKRARMPPGSTGLPLIGETLRLISAYKTPNPEPFIDERVARHGGVFTTHVFGERTVFSADPAFNRLLLAAEGRAVHSSYPSSIATLLGARSLLLTRGAAHKRLHSLTLTRLGRPASPPLLAHIDRLVLATMRQWEPAATVRLMDEAKKITFNLTVKQLVSIEPGPWTESLRREYVKLIDGFFSIPFPLAYFLPFTTYGQALKARKKVAGALREVIKKRMEEKAENGGSIGDDEGKKEKKDMVEELLQAEGGSFSEEEMVDFCLSLLVAGYETTSVLMTLAVKFLTETPAALAELKEEHANIRDMKGKNQPLEWSDYKSMPFTQCVINETLRVGNIISGVFRRANTDIHYKDYTIPKGCKIFASFRAVHLNNEHYENARTFNPWRWQINNKLQNAVGANIFTPFGGGPRLCPGYELARVVVSIFLHHLVTRFSWEETEEDRLVFFPTTRTLKGYPINLRLLSESIC
What is the function of this protein?
Catalyzes the C23-alpha-hydroxylation step in brassinosteroid biosynthesis (Probable).  Converts 6-deoxocathasterone to 6-deoxoteasterone in the late C6-oxidation pathway and cathasterone to teasterone (TE) in the early C6-oxidation pathway of brassinolide (BL) biosynthesis (Probable).
What are the official names of this protein?
Cytochrome P450 90A4, OsCYP90A4, Protein CONSTITUTIVE PHOTOMORPHOGENESIS AND DWARFISM 2, OsCPD2, Steroid 23-alpha-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SELA_SULDN
Sequence: MFLLKSIPQVDKFIKNEKFASLPLTLLVQITAEVLQDLRERILKNEIESFSEDELVKKVLQKYKDITKPSLQKIINATGVIVHTNLGRSLIDANAFERVKGIVTSYNNLEYDLEKGKRGERYSHISDAICRLLGCEDVLIVNNNASAVFLILNTFAKQKEVVVSRGELVEIGGSFRVPDVMKQSGAKLVEVGATNKTHLYDYENAISKKTSMLMKVHKSNYSIEGFSSEVEFKELVKLAREKNLIDYYDMGSGHLVNLPYGLDQHEPSVLKYMQENPSLLSFSGDKLLGSVQAGIIVGKKEYIAKLKKNQLLRMLRVDKLTLALLEDSVISVLLNKLDEIPTLKMLFASTCELKENALVLQDAIKDICDCEVLETKTVIGGGTTPNKMIPSIALAIKIDNYKQNKMEKLFRAKNIIGRIENDRFLLDFRTIRKSEIQEIAHVVKEIANV
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH_SHEPA
Sequence: MTSKIKCALIGSGNIGTDLLYKLLRSDVLEPVWMVGIDPDSDGLAKAKAAGLKVTADGIDGLLPFVEADEIKIAFDATSAYVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLEQLDENINNINMVTCGGQATIPMVAAVSQVQAVEYGEIVATVSSRSVGPGTRQNIDEFTRTTAGAVEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKDQPDEQAITASVHKMIEQVQQYVPGYTLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNVKTHLNVTKEAALA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: Y1640_SHELP
Sequence: MAFDKKLLEIVACPVCKGKLEYDKANQQLICKADRLAYAINEGIPVLLENKATPWNEEA
What are the official names of this protein?
UPF0434 protein Shew_1640.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: YOHJ_ECO24
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAISTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROK_BURL3
Sequence: MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEAGFRDRETQVITDLTQRENIVLATGGGAVLRPENRDCLKNNGIVVYLRANPHDLWLRTRKDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPSVNGLVNMVLMQLELAGVIAKPLQA
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_CHLPB
Sequence: MKVHLDRTSSGFCIGVQGTIHLAEEKLEELDSKLYCLGDIVHNEVEVKRLEDLGLITIDNEEYNKLKHAHVLVRAHGEPPSTYKRADSNELSITDSTCPVVSKLQRTARLLFELGFQIIIYGKKTHPEVIGINGQCADQAVIIKHADLSVPEETDPIDFTRQTALISQTTMDVPGFYILKKNLESLFADRTDAAEQKSTHSWKTIRDIDITAEMTGICPLPDLVYKDTICRQVSSRNAKLHDFAAANDIIIFVAGKKSSNGQVLFNICRESNPRSYFIADQTGLQDEWFYDNGRPVGSVGVCGATSTPMWLLENVAHSIEQTYAG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: TREC_ECOLI
Sequence: MTHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQHLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYLHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLDGDGRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALADDSSVFYTYQKLIALRKQEAILTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSREIQPWQAGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK
What is the function of this protein?
Hydrolyzes trehalose-6-phosphate to glucose and glucose 6-phosphate.  Can also very effectively hydrolyze p-nitrophenyl-alpha-D-glucopyranoside, but it does not recognize trehalose, sucrose, maltose, isomaltose, or maltodextrins.
What are the official names of this protein?
Trehalose-6-phosphate hydrolase, Alpha,alpha-phosphotrehalase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGRO1_DICDI
Sequence: MEKKLLIIVIVFLFSTIQVFCRIDDKTFVISNETYLSYHFPVDSEYFSSLNFEHYEGPSFQLDFECITFNGTICFSQIYPEIKKKIYGTSISYSTQKTYKLDQELFPTPIVSSPFQPPTKGGISILKGTFLTFSEKTFYQVIYPKKQKIFILDSESLSFDATNFKVNCPPGCGYQIIKWDNGNLFNFSYSNPSISVVKINPSNIIVNGSDFCDSSYSSNITIDGVIIPNSNYEKDEDSIVIIYTQQHTIKSLMKIETSNVTSVEIEIVFKPEPLLINSVPYSKGGLLILEGLRLSSNTTNKNNNNNNIIIKIGNITCSNAISISNDSITCNLNPGFNNKSVTLNNLPVSVTINNITNENKLLFNYGIVKLNPNKYSLPDRVLQLNGDCLGNSNGTIVYLNGKETLLNDLKINNQETTLSFKIPDEFKSKLNVSIKVNDILSNEIQIDISFYASHSNEQPSTNGNTNIIFTLYNIKSENYNKIPSIIIIPEQIVINGVSVNSPTNQDVHSYSFLIPAGCGKKDIQIIIGSQSCLSSITYFEPIIKNCLVSGFDGTNGNIICDGSFGNKDYLIKSSVLFSNDEIIPPSINSTTFSFPLISGYHSDDLIFQMCGVQSKPFKLNISPSLKGINQSQMETLGGKFYILGEFFSANINCSVFCNDKEYEKKFENSKTISFDLQIPGPNDITCNYTFDNGKNTGDFKIEYPLPLIENTSSINVNGGNLTIYGKNFYNVSNIKVEVDNQLKCNKIEFINLNSLTCFLPPFIETLFNDQKLLLNSSTTIFSKKLLLNVTFESKTWSGYIFQYSKEEIKNNDTSENSTNDILNHEKNNNNQKDGSSLSKKSIILLSILLPSFIILIVSLAIVILVIKRNKTKHSKNMSSKEKELMKQ
What are the official names of this protein?
Tiger protein O1, Transmembrane, IPT, Ig, E-set, Repeat protein O1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MTP_HUMAN
Sequence: MILLAVLFLCFISSYSASVKGHTTGLSLNNDRLYKLTYSTEVLLDRGKGKLQDSVGYRISSNVDVALLWRNPDGDDDQLIQITMKDVNVENVNQQRGEKSIFKGKSPSKIMGKENLEALQRPTLLHLIHGKVKEFYSYQNEAVAIENIKRGLASLFQTQLSSGTTNEVDISGNCKVTYQAHQDKVIKIKALDSCKIARSGFTTPNQVLGVSSKATSVTTYKIEDSFVIAVLAEETHNFGLNFLQTIKGKIVSKQKLELKTTEAGPRLMSGKQAAAIIKAVDSKYTAIPIVGQVFQSHCKGCPSLSELWRSTRKYLQPDNLSKAEAVRNFLAFIQHLRTAKKEEILQILKMENKEVLPQLVDAVTSAQTSDSLEAILDFLDFKSDSSIILQERFLYACGFASHPNEELLRALISKFKGSIGSSDIRETVMIITGTLVRKLCQNEGCKLKAVVEAKKLILGGLEKAEKKEDTRMYLLALKNALLPEGIPSLLKYAEAGEGPISHLATTALQRYDLPFITDEVKKTLNRIYHQNRKVHEKTVRTAAAAIILNNNPSYMDVKNILLSIGELPQEMNKYMLAIVQDILRFEMPASKIVRRVLKEMVAHNYDRFSRSGSSSAYTGYIERSPRSASTYSLDILYSGSGILRRSNLNIFQYIGKAGLHGSQVVIEAQGLEALIAATPDEGEENLDSYAGMSAILFDVQLRPVTFFNGYSDLMSKMLSASGDPISVVKGLILLIDHSQELQLQSGLKANIEVQGGLAIDISGAMEFSLWYRESKTRVKNRVTVVITTDITVDSSFVKAGLETSTETEAGLEFISTVQFSQYPFLVCMQMDKDEAPFRQFEKKYERLSTGRGYVSQKRKESVLAGCEFPLHQENSEMCKVVFAPQPDSTSSGWF
What is the function of this protein?
Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:25108285, PubMed:22236406, PubMed:16478722, PubMed:15897609, PubMed:8876250).  Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:8876250, PubMed:16478722).  May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (By similarity).
What are the official names of this protein?
Microsomal triglyceride transfer protein large subunit.
Protein: Y096_MYCPN
Sequence: MLLGLGIVVLIYSLIALSVSLTTPNGAFSGLGDWLKHKKLGWFFGVLNLLIALGVAGIINGFVMWTGKLTQSLIKSGELWVPDKCKLCLNKPKPVVGLIHAGILMVLTTVALSSLGGLLYLPKVNASYDGKGFKSMGCLLEFADLIATWTSVGIFWFLGLVLLGGLLQIKKPKRWYFRTTGWLAVVVIGLTTLVVMVQPFVDLGIAVFNRSYERIVANTILIAILVIIVLVMFFPTEPIKLRLWRKRIQAMEACGEDCDACVEY
What are the official names of this protein?
Uncharacterized protein MPN_096.
What is the protein family that this protein belongs to?
To M.pneumoniae MPN_308 C-terminal region.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSY_ECO81
Sequence: MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUTF_ECOLC
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: 1433Z_PONAB
Sequence: MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB.  Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (By similarity).  In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity).
What are the official names of this protein?
14-3-3 protein zeta/delta.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes.
Protein: PBCF_EMENI
Sequence: MVDATSPPGVNAVVNYYVPNSDGSPPATNDMAVMLGQKDMISHKMRIRDLRPYKEEYSLDRNGFQYATIHSTLTDATDETQIKEVYYREIEKLVQDITGAKRVLAFHHAVRTRTGNEFGEQIKDRYQGVEGPAYRVHIDQTPQGALSIVQFMFPDLADDVRNGSFQVINVWRPLTRVQRDPLMVADAAEMPPEDLLLISRKYYNGLHSSNFVIKYDGRMAAGEGPTDGLSGDGKHSWWYIGDQEPTEALVFSSSGFRNGKAIIGTAHDLYSAEPMINAYERKNASSLYGHDESQI
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of the diterpene ent-pimara-8(14),15-diene (PD) (PubMed:22506079, PubMed:27098256).  Within the cluster, the HMG-CoA reductase AN1593 functions in the mevalonate pathway, which produces isoprenoid precursors (PubMed:22506079, PubMed:27098256).  The geranylgeranyl pyrophosphate (GGPP) synthase AN1592 is needed in the formation of GGPP, the precursor for diterpenes (PubMed:22506079, PubMed:27098256).  Lastly, the pimaradiene synthase pbcA performs the 2 cyclization steps that convert GGPP to ent-pimara-8(14),15-diene (PubMed:22506079, PubMed:27098256).  The putative roles of the remaining cluster enzymes in ent-pimara-8(14),15-diene biosynthesis is unclear (Probable).  The cytochrome P450 monooxygenase AN1598, the glutathione S-transferase AN1595, the oxidoreductases AN1596 and AN1597 probably function as decorative enzymes (Probable).  It is possible that in biological conditions the compound is oxidized to ent-pimara-8(14),15-dien-19-oic acid, which is a bioactive diterpene compound predominant in many plant extracts (Probable).
What are the official names of this protein?
Oxidoreductase AN1597, Pimaradiene biosynthesis cluster protein AN1597.
What is the protein family that this protein belongs to?
Belongs to the asaB hydroxylase/desaturase family.
Protein: GCSH_SHESW
Sequence: MSNIPTELKYASSHEWIRKEEDGSYTVGITEHAQELLGDMVFVELPEVGDTVTAGDDCAVAESVKAASDIYAPISGEVIAVNEALEDSPELVNSDAYGEGWFFRVMPSDETEVDALLDAEGYQAVIDEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: VPP2_BOVIN
Sequence: MGSLFRSETMCLAQLFLQSGTAYECLSVLGEKGLVEFRDLNQNVSSFQRKFVGEVKRCEELERILAYLVQEINRADIPLPEGDTSPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRKNLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPPLENESLLDYSCMQRLGAKLGFVSGLINQGKVEAFEKMLWRVCKGYTIVTYAELDEPLEDPETGEVIKWYVFLISFWGEQIGHKVKKICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVIQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLHELRRALEEGSRESGGTIPSFMNTIPTKETPPTLIRTNKFTEGFQNIVDAYGVGSYQEVNPALFTIITFPFLFAVMFGDFGHGFVMFLFALLLVLNENHPRLNQSQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVNLFGSRWNVSAMYSSSHSPEEQRKMVLWNDSIVRHHSVLQLDPSVPGVFRGPYPFGIDPIWNLATNRLTFLNSFKMKMSVILGITHMTFGVILGIFNHLHFRKKFNICLVSIPELLFMLCIFGYLIFMIIYKWLVYSAETSRTAPSILIEFISMFLFLASDTGGLYPGQEHVQRLLLLITVLSVPVLFLGKPLFLLWLHRGRSCFGVGRSGYTLVRKDSEEEVSLLGGQDIEEGNNQMEDGCREVTCEEFDFGEILMTQIIHSIEYCLGCISNTASYLRLWALSLAHAQLSEVLWAMLMHVGLRVDTAYGVLVLLPVIAFFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFRLLSSKFSDDLA
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Essential component of the endosomal pH-sensing machinery (By similarity).  May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH (By similarity).  In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).
What are the official names of this protein?
V-type proton ATPase 116 kDa subunit a 2, V-ATPase 116 kDa subunit a 2, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane.
Protein: DNRC_STRS5
Sequence: MQDSSYKKQVTQAFDQSSSTYDRLGVEFFTPMGRRLVDISEPVTGERVLDIGCGRGACLFPAAEKVGSQGCVHGIDIAPGMIEEARKEATERGLRNISLMVMDAETPGFPARSFDLVMGSYSVIFLPDAVGALARYADILDHGGRIAFTSPVFRAGTFPFLPPEFTPLIPQALLEHLPEQWRPEALVRRFNSWLERAEDLVRTLEGCGYARLRQSTSRCG
What is the function of this protein?
Involved in the biosynthesis of aklavinone which is an important precursor common to the formation of the clinically significant anthracyclines such as carminomycin, daunorubicin (daunomycin), rhodomycin, aclacinomycin T (aklavin) and aclacinomycin A (aclarubicin).  These compounds are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.  Catalyzes the methyl esterification of aklanonic acid to yield aklanonic acid methyl ester.
What are the official names of this protein?
Aklanonic acid methyltransferase DauC, AAMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. DnrC family.
Protein: SYFB_CHLCV
Sequence: MRVSLSSLQRFFSSPLPIKQIIEACDHIGIETEVETLLTCSFSSIITAKVLKTVPHPNADKLVVATLFDGQQEYQIVCGAPNCRPGIIIPLALPGAKLHDHEGNAYTIKKSKLRGVESQGMCCGADELGFAHLQTTERGLFEFPENTPLGESACALLADTFIECSLTPNLGHCASLLGLAREITYVTNVDLVLPPEFVCTPLETITKETSGQDQHLCPIFCCVKISGVSAQASPQELQNALGGLKQKSINSIVDITNYIMLSLGQPLHVYDANAVDIDSLHAQKAQKDEPLKLLNNEEVLVPQGTAIICDKDHTVGLAGVMGSLDSSFNDATTEIILEAAYFLPSAIRASQTHVPIHSEAAYRFTRGIDPNNVLPALYAAIHYIQKLFPNAKVSPIQVLGSTPQASTLSFRTELVGKILGMPLHASQVRDQLHSLGFNISSEENSILSVNIPSYRHDIQEEIDLVEEVCRTQPWKVENKKAPAIYSPMYSLKRRVVDFLANSGLQQFFTCDLLDTETAALNREEADCISLQGSKQATVLRDSLLPGLLKSTATNLNRQAPYVHAFEVGTTYTKKSSKYQETQSLGIILSGQAEEISWISHERPLSFYSIKGWIERLFQYLHVSSQAYAIQPYEHANFHPYQQAEIHLHKHVLGRFGTLHPQLCKKAQIKHSVFFAELSLDSLLHTQKKALHLYKPYPIYPSSFRDITLTVHESVPADSLRKKLLSFHSKWLESVSIISIYQNKNPTTQNKNVSLRLVFQDKERTLSNQEIEEEHERLLAMLNAQINDTKGTID
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_MYCTU
Sequence: MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAARLWPTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVGAAGGREAAARSARYSALEEHRDGPVLLAHTLDDQAETVLLGLGRGSGARSIAGMRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTEVLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRGQELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVTAWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SALL3_MOUSE
Sequence: MSRRKQAKPQHLKSDEELPPQDGASEHGVPGDGAEDADSGSESRSGSEETSVCEKCCAEFFKWADFLQHKKTCTKNPLVLIVHDDEPAPPSEDFPEPSPASSPSDRTESEVAEEVAPTEGSEVKAATKEAEPMDVEVSTDKGPPGPSVPPPPPALPPQPEPAAFSMPSTNVTLETLLSTKVAVAQFSQGARAGGTTGAGGSVGAVAIPMILEQLVALQQQQIHQLQLIEQIRSQVALMSRQPGPPLKPSASAPGTASVQLQGLTPHAALQLSAGPATASAGSGSTLPAAFDGPQHLSQPASGTSTPCSTSAAPPDSGAHPACSTGPAPGAVAAASSTVGNAVQPQNASTPPALGPGPLLSSASNLPNPLLPQTSSSSVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGTHNYTDSPSITPVSRSPQRPSPASSECTSLSPGLNNTESGITVRPESPQPLLGGPSLTKAEPVSLPCTSTRTGDAPVVGGQVSGLPTSAATAVTDSACTSLGSPGLPAVSDQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGLQEAMDADLPFDEKNAETLSSFDDDIDENSMEEDSELKDTASDSSKPLLSYSGSCPPSPPSVISSIAALENQMKMIDSVMNCQQLANLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAHSNGESFRSKSPGLGHQEDPQEIPLKTERLDSPPPGPGNGGALDLTAGHPGRPLIKEEAPFSLLFLSRERGKCASTVCGVCGKPFACKSALEIHYRSHTKERRFVCTVCRRGCSTMGNLKQHLLTHKLKELPSQVFDPNFTLGPSHSTPSLASSPAPTMIKMEVNGHSKAIALGEGPALPAGVQVPTGPQTVMSPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGGAIPPLGAMASGVDKARTGSSPPIVSLDKASSETGASRPFARFIEDNKEIGIN
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Sal-like protein 3, MSal, Spalt-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the sal C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VREP_BPPHH
Sequence: MHRRVEWMTPTDDAILSLLGPPKQLELRSGDIARNTGYSRRRISDRCTVLVDRGLLFRDDEAGHPYYGLTDFGERYVAGELTVDNLEKA
What is the function of this protein?
Possibly prevents RNA polymerase access to the promoters for lytic cell cycle transcription.
What are the official names of this protein?
Putative repressor.