PharMolix/UniProtQA huggingface dataset:
Protein: DUT_GLAP5
Sequence: MKQIDLKILDKRIGTEFPLPTYATTGSAGLDLRALIEQPLTVEAGQTVLIPTGISVYIADPNLAAVILPRSGLGHKNGIVLGNLIGLIDSDYQGPLMVSLWNRSDKPFTVEVGDRIAQLVFVPVVQAQFNIVEEFTATDRGEGGFGHSGKQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PILP_PSEAE
Sequence: MRARLILSSLLLASLAGCGGGSDFADLQSYMDEVRARPKGTIEPLPKFQPYEAFTYSAASLRSPFQPPVKIDLTVRQKGNKVIKPDETRVKQFLEGFNIETFEMVGTLSNAQGTFALVKGAGGVHRVRVGDYLGRNDGKVVGISEGKIDVIEIVPDGEGNWLERPRSLTLKERS
What is the function of this protein?
Inner membrane component of the type IV (T4S) secretion system that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility.  PilN/PilO heterodimers form the foundation of the inner-membrane PilM/PilN/PilO/PilP complex which plays an essential role in the assembly of a functional T4 pilus (PubMed:19857645).  PilP connects PilO to the secretin PilQ.  In turn, the PilM/PilN/PilO/PilP/PilQ complex facilitates transit of the pilus through the periplasm and clamps the pilus in the cell envelope (PubMed:23457250).
What are the official names of this protein?
Type IV pilus inner membrane component PilP.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: Y1279_MYCS2
Sequence: MDYDAITALRDRHPAWRLLRAGNASLVLSFLGEFFVEANRGACPAGQVAEALDNHLYALSAGSGESRYPKEPRAYLEDWAATDAGYLRRFYPPGDDEVHYEVTPAFEKAYAWVVNLQSRSFVGTESRLHTVVALLRQIVHGTEVQPDVRLAELRRRRAELEAEIAAVEAGDIAVLDPTAVRDRYQQLSTTARELLSDFREVEENFRLLDRAARERIAAWEGSKGGLLEELVGSRSEITGSDQGRSFQAFYDFLLSEQRQAELAELIAKVSALDVLEADPRIRRIHHDWSEAADRAQRTVRQISEQLRRFLDDQVWLENRRVLDLVRAVESIALEVRDAPPTFGLEVDEPGIEIALPFERPLYQPPTEVAVESHVSAATEEVNADLLFAQTYIDQARLADTIRAVLPEDSSALLSDVVAVHPIEQGAAEIVGYLALNEDDLAIDVDDTEETVLEYPDPADPDITKRARLPKVTVRRR
What are the official names of this protein?
Uncharacterized protein MSMEG_1279/MSMEI_1241.
Protein: CISD2_DROSI
Sequence: MEPISHLVKSSLPNYLSSLPVPDSIGGWFKLSFKDWLALIPPTVVVAGIGYTAYLAYCPAARASCSAKISGRCNNQIRKNEPKVVDMIDVEDIAEKAAFCRCWKTKNWPYCDGSHGEHNKQTGDNVGPIVIKK
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RL20_LIMRD
Sequence: MRVKGGTVTRARRKRIMKLAKGYRGSKHRLFKTAKDQVMKSYAYAFRDRKVNKRKFRELWIARINAAARMNDISYSKLMHGLKVANIDINRKMLADLAVNDADAFKALVDEAKKALN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CMOB_SHESW
Sequence: MISFSSFYQQIADSNLQHWLETLPSILGKWQRDHKHGNLPKWEKVLNKLHYPAPDQVDFVDSVTVGSGEQLSPGEKEKLENLLRLFMPWRKGPFHIHGIHIDTEWRSDWKWDRVKQHISPLNNRTVLDVGCGSGYHMWRMLGAGAKRVVGIDPSPLFLCQFEAVKRLAGAHHPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRTGGELVLETLVIDGDENAVLVPQDRYGKMNNVWFIPSVAALMLWLKKCDFTDIRCVDTDVTALAEQRRTDWMPNESLLEYLDPTDITKTIEGYPAPKRATIIAIKNQPNQETVNG
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: C2CD3_XENTR
Sequence: MKSRKVKSVRPGRGRILGLTDVTPSTSLPPLVEGQVRSFLQVTVSKILWTVPKPPPSVLVRLRWWGETANGTVFRPRDSSQTEQKGAKTTTRYAVRCGPKQFTSYLTDMGMLVFEVMTKLDHFPIGRAQISGIAQLSLAHPVSGFFTIVSPTSEKLGELQVSVQLEPLPETYDSSSSAPNTDISFDHASESYGKALTGHPTTMNDPPQPIILSLASADKRESESSSRVTTPRGRDHLYFQENADPGKDSYRGTQDHVTVGWSNVTEGVQSIKPIYSEGTTAGKDALTVNSGPATKDLLSALLDQGSKLRDAMVVSALKSSPDLDHNPDIKLPLALNNYSLSQARATSEIPSPTLMRNLLNSRHSPQTRDILLQPADSFIPDMEAPSDAKAIELLLGSSVLSPGHYWDGTGSPPESISGSDFYNESELNDPLYDQSLLEKLFYKAPKSDSSASDFMSDDENTRSQNKKNKIALDRGRHRDNSPSEYKEDAKQTKGNDSLRDSKTSEKSTSRCEGISLSMDQAALLGQIHVAHVVVESLRVPLDGTAVTPSKTNSRGRPPRPVRPAKQTFFVEFQFPVLSKSRSGEVNSATEITRLVSSKVVNGSIKFQQRFTFPVLFSGQMIKHWWNTDLTFRIFLRKGTQNKPGPVGSATLPLRDVLQSPGLSVTCSLPVSCTAEDSHTAAGPLKISVALAGDNKNIHDISEKTLEPENQAPVLPAVTSKAELENSASYTDLRPVAEKSSPLRQSLPPHIGNGGPKVSFSQNPQQTAEEDGLLLHIVLMVPEGKGLVAAGGDSSGICNSYLNCKLFSAQEATRSSVVWGSTQPQYNFSQVAPLTLNARLLERMKNNVMIIEIWNRVASPGQDQLLGLAKLPLHQFYMSFSDPKITRLLLQAQYPVVAVDSYVPIIDVFSGCDRGKLKVLLAIGSGDQVVALQRLKNEEGTSQTAMPRPAHFLDPPLSSSQMGRPQEGMTDHIFEIHVENVKGLTPLQSTVWGEADCFVQYYFPAHGPDSHTAIDLPEIAMTLKPVRTATTLCVPDPVFNDRQSHTIVAQSDTPVQRLLLGAYSMQGLSGGGGVPFEIWCRYYYPNVRDQMVAKGVLPLSRLCAMVTMQHREDVGIQAFSLPLIPRSEKSAELPPQPSGLLNVNVTYRRSMRNPVGMLATRMASISVQIHRASGLQAAARLVAQQDASFQYSADVGVNAYVTIHPAFLPDVELRNTRTVARTFCPEFDHHYEFPCNMVIQRNNGEACSLAEVLYFSEIVLSIHHQNVASVGSTRPQPVRDYHLGMVRIPCRQLITKRSGVSGWYPVTVPEDSKLPTDSTILHSVVGGLELSVHFAHHSDRDRVLEVARGLGWNEYNEDFQEAIATEADEWHKREDLVNLSVNIPKIWLPLHCLLLAGHKHIHKSTYCYLRYKFYDREAVCSPLRRPRLSEDGQQATIMFELSENRELIKHQPLVWYLREERMEIQVWRSYGKDTNGPRPQDTDRLIGCAYVDLKALSENTSRTLAVSGVYPLFKRNVSSLWGAAVRVHLALSSAYHPSNSSRRLSCAGERSQSEGEEWAPTSGDSFEEKQDDSAKNDKPEAKTEVPLLDAKEQPVGEVDLKNTFAASIVVERAMHLSLKGTPLTERAAATPTCCVSYPVAGCSEPVTTPVIANTDSPLWNFQHQARLHKELLLDPQQRLVFKVWHKTDVERVVGFASVDLSPLLSGFQSICGWYNIVDFVGQCQGQVKVSITPLEGVAHLKTKVTSQRSSSYQSRPAFCSSFSYNPSQSEVPAFIPHIPTLHHQLSDRENSGPLFPFLRHEEHMENVRRFHESLQQAERNAHTVEGLDSLSQSSRSSLLSALRKNLGELDEIQKYFNQKLYRSISNAETSRCASVQIPQVQPPNSEPAEEDSDAKMLLQKSSFLVSQVSNLITGLQGIPKFAPAFSSTEQRLDVQGQTSVQHQQVDNMEPMAPERSEAYEREGQRSDTPPFSPLGSLNVSGEKLMEFIGTDMDEKERHLFAEKHQEEQDKHIIHGSSDEEYEEDVIEPRTLNEITTMTDRTSPWSSILSERDSDSMDHPQDQPVNPLAAENNRVITDFFSSFHQNDPSSVLSSARSTDSEVLAEGSRVRKISSSSGSEAETVGVQLSVDPAEQGALGEAESEAESQEMDGDPEANRTEEEQQDPVTVFSALSSGSDESEHITYGASEPDCSPPQDEPETDYPCSEPLEGNMHHIDEEEQPAGSESPQVPPSNLLSDPVIVPNFFLPPQHLEASMRHLSLSAVREGRSDTPGIPFRRSKRQKPRLAPADLPKEETNRIARIFAAQFPGPPTPP
What is the function of this protein?
Component of the centrioles that acts as a positive regulator of centriole elongation.  Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium.  Required for primary cilium formation (By similarity).
What are the official names of this protein?
C2 domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centriolar satellites. Also localizes to the distal ends of the mother and daughter centrioles (By similarity).
Protein: UVRC_LACE2
Sequence: MFNLEEELKKLPAKPGVYIMHDKWDNIIYIGKAKVLKNRVRQYFQSNRNKSAKIVQMVSHIQYFEYIITDSELEALVLECNLIKEHRPKYNTMLKDDKSYPFIKITVGEEYPRVLFARKMKHGAGKYFGPYTSAAAVKDTIELLCKLYKVRTCNRNLPKDEGRDRPCLNYHIGQCDAPCQGYVSGEEYRRRIDEVVAFLNGDYKKIMDRLTTQMQEASEKMEYEEAARYRDLLMSVKQVAQKQKITADDVNDRDVIACASDGQDAVVQVFFIRQGKLLGRDHFHMKVAEGDSKSDIISEFMKQYYGGTPFIPNIIMVQYEIEDADTIAQWLSARKSRKVSIVTPKKGDKEKMVELAYKNAQLVLTQDAEKIKREESRTTGAMKEIAGWLGLGTLHRAEAYDISNTNGVESVGSMVVFEDGKPKKNDYRKFRIRTVKGPDDYKSMREVLTRRFTRGMREREGLEDSHGFSRYPDLIMMDGGRGQVNIALDVLKELGLNIPVCGMVKDDTHSTRGLYYNNIEIPIDKHSEGFKLITRVQDEAHRFAITYHRSLRDKAQVSSVLDSIEGIGPVRRKALMKHFLDIEKIRQASVDELMKADGITENVAENIYKFFH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_ECOL5
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQVMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSQELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNLJ_CLONN
Sequence: MEDKKLLIYELVEELNKLAYEYYVLDNPSVSDKDYDKKYDKLVELEKETGLVLPYSPTQRVGDVVLSKFDKYTHKGKLWSLGKAQSLKEVEDWHNKNVKAVNEYNLTHDDKLPPIKYIITKKFDGLTINCTYNEDGILVTAATRGTGEIGEEITAQAKTIKTIPLKIDNDAVIEVHGEAIMTKEAFEEYNKVAVVPLKNLRNGAAGALRNLNVKETARRNLSAFFYDIGYNEGTPFKTYGEMLKFIKDHGIPMDDYAMECSTIEEIEKEINYIEEIRNKLNYDIDGAVIAVDDMKTRELLGYTVKFPKWALAYKFEAQEATTKLLEVEWNVGRSGRVTPTAILEPVEIGGVTVKRATLNNMDDIERKGVKLGSTVFLRRSNDVIPEIMGVVEESLEGSKDIEAPTTCPYCGSEIVQEGVHYFCENTLSCKPQLVKSIVHFGSREAMNIAGFSEKTAEQLFEELEIKSISDLYRIKKEDLLKLNRFGEKKAQNLIDAIESSKECDLPSFIYALGIPNVGKKTSTDLCKKFKTLDNLKKAKFEELVSVEDIGDIVAQSVLDFFNDETILKSIDELLSLGVTPKFKEEEIKENIFNGKTVVVTGSLSSFSRNEIKEKLQSLGAKVAGSVSKKTDYVLVGKDPGSKYEKALQLNIKIISEEDFKNMIG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ALF_BUCAP
Sequence: MKILNLIQPGVVTGNECQIIFELAKKKKFAIPAVNCIGTDSINAVLETASRVKSPVIIQFSYGGASFIAGYKRTSSKNPEDQAIQGSISGAQHVHLMSQYYQIPVILHTDHCSKEMLPWIDGLLEEGKKHYKNFGKPLFTSHMIDLSKEHLKENIAICSNYLKKIKKINMILEIELGCTGGEEDGIDNSNIDKKLLYTQPKDVNYAYKKLSKISTNFTIAASFGNVHGVYQPGNVNLKPNILKESQEYVSTKHNLKKLPLNLVFHGGSGSDLKEIHESIEYGIVKMNIDTDIQWASWKGVFNFYKKNKDFLQKQIGNKNGKNIPNKKYYDPRSWIRESQESMSKRLEKTFKDLNAFNIL
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase class 2, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase, Fructose-bisphosphate aldolase class II.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: CBIA_PRIMG
Sequence: MSNRRLVIAGTGSGVPKTTLTIGLMAALKQAGYRVQGFKCGPDYIDPTYHTAVTERTSRNIDSWMLEHDMVREIVARASQDADISIMEGVMGFFDGKNPLTNEGSTAEISLITNSPVLLVVNCASMARSAAAIVKGFQQFLPEANIVGVIANRVGSEGHYKLVKAAIEQECHIPVVGYLKTNDELTIPERHLGLIPSIERGELTPFFEQLGQLVHDTIDIEKVYELALAPKIEINDPIFTKPSVPQVKIAVARDAAFNFYYEENFELLKACGAELVEFSPLKGEMVPQDADGLYIGGGFPEEFAETLAQQIDVKNSVRAAIQKGLPTLAECGGFMFLTDGIVTTDDTCYEMVGLIPGQVRMQTKLAALGYREVTGKPGNFLFKGDIQAKGHEFHYSTFYSEKEFSPAYDTKGMRGMKEEGYMNNNLIAGYTHFHFGSSTKMVENWVEQCKAAKKERRDAV
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: LEUD_METTH
Sequence: MKGKVWKFPDDVDTDIIIPGRYLVMRDPEKLREHVMEGLDPEFPSKVKPGDFIVAGKNFGCGSSREHAPLALKGAGIAAVIAESFARIFYRNAINVGIPLLEAPGITEKLNEGDEIEVDLDRGVIIRGDDEFPFKKLPDFMVEILEKGGLIPYLKKKGDFKG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: SYP_MANSM
Sequence: MRTSKYLFSTLKETPNDAQVVSHQLMLRAGMIRPMASGLYNWLPSGIRVLEKVKNIIREEMNKSGAIEVLMPVVQPAELWQESGRWEQYGLELLRFNDRGNRDFVLGPTHEEVITDLVRREVSSYKQLPLNLYQIQTKFRDEVRPRFGVMRSREFIMKDAYSFHTTKESLQATYDVMYQTYSNIFTRLGLDFRAVQADTGSIGGSASHEFQVLASSGEDDVVFSTESDYAANIELAEAIAVGERAQPGAAMQLVDTPNAKTIAELVEQFNLPIEKTVKTLIVKGATEEQPLVALIIRGDHDLNEIKAEKLPEVASPFEFADEADIKAKIGAGVGSLGPVNLNIPVIIDRSVALMSDFGAGANIDGKHYFNINWERDVALPKIADLRNVVEGDPSPDGKGTLLIKRGIEVGHIFQLGQKYSEAMNATVQGEDGKPLVMTMGCYGIGVTRVVASAIEQHHDERGIIWPSDAIAPFTVAIVPMNMHKSESVQAYAEELYQTLLAQGVEVIFDDRKERPGVMFADMELIGVPHMVIIGEKNLENGEIEYKNRRTSEKQMIAKDQLLDFLKANVNV
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTYBC_VIBCH
Sequence: MAKITQTMMAQVLSLVGGSGNVAKCGNCMTRLRLTLNNSALADHAALKKISGVMGVVESDAQLQIILGPGKAQTAADMMNALIESGDNVAPAVSEADLSTIAAQQKKQMKSKQTSAVQRFLSKFATIFTPLIPGFIAAGLLLGIATLLEQIYVVGQTPSEFMLDLVAYLKVFGKGLFAFLSILIGYNAQQAFGGSGVNGAILASLFVLGYDPEATKGIYSGMSEFFGFAIDPRGNIIGVLLAAILGAQVERKVREYMPDDLDMILTSVVTLLIMGAVTFLIIMPIGGELFKGMSWLFLNLNDNPLGAAILAGLFLISVVFGIHQGFVPVYFALMEAQGFNSLFPILAMAGAGQVGASLALYARAKKETTIRTQIKGAIIPGILGIGEPLIYGVTLPRVKPFVTACIGGAAGGFFIGLISYLGLPVGLNTVFGPSGVVAIPLMTSADGIFAGMAVFVGGLLISYTVGFAATYFFGCKDVDLS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P.  Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
What are the official names of this protein?
PTS system N-acetylmuramic acid-specific EIIBC component, EIIBC-MurNAc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GGR_THEGJ
Sequence: MSWKYDVVVVGAGIAGPIVARNVARAGFSVLLIDKKWAIGTPKQCAEGISIKVFEKYDIPYDKRFINREIYGAKLYSPSGYELEMRYKDVSGVILERKVFDKMLAYYAAKAGADVLARTEALDVIRKDGKVVGIKAKHEDEPIEIYADVIVAADGVESTIARKAGINTYAPPHEFDSSYEYEMLIEGFDPDLIHLWFGNEIAPRGYVWVFPKDEDRANVGIGINSDNPQTAKYYLDKWLKENNIPAKKLLEINVGVVPVGGFVKELVKNNVLVVGDAARQVNPMHGGGMAEAMEAGTIASKWIVKALEEENLSLLQNYTKEWWETDGKRLEKVLKVRRVTEKLTDEDLDLFIQVLSGADAEKIAGGDYGEVIKALLKHPKVLMSKRRLSLLKSLL
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: SIGZ_BACSU
Sequence: MNIEDLWDQFHQPLKTYISHRVNDQSIVDDLLQIVFMKIQVHLPNLIDEQKIDSWIYRITRNTIIDFYRTKKTSEILPDVLHFNDSAEEENFTKEATVCIRSTIKRLPEKYREALELTDFQGLSQKELSEKLGISYSGAKSRVQRGRGKLKQLLEGCCHIEADRYGNIVDFRILKE
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
What are the official names of this protein?
RNA polymerase sigma factor SigZ.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: FUS1_YEAST
Sequence: MVATIMQTTTTVLTTVAAMSTTLASNYISSQASSSTSVTTVTTIATSIRSTPSNLLFSNVAAQPKSSSASTIGLSIGLPIGIFCFGLLILLCYFYLKRNSVSISNPPMSATIPREEEYCRRTNWFSRLFWQSKCEDQNSYSNRDIEKYNDTQWTSGDNMSSKIQYKISKPIIPQHILTPKKTVKNPYAWSGKNISLDPKVNEMEEEKVVDAFLYTKPPNIVHIESSMPSYNDLPSQKTVSSKKTALKTSEKWSYESPLSRWFLRGSTYFKDYGLSKTSLKTPTGAPQLKQMKMLSRISKGYFNESDIMPDERSPILEYNNTPLDANDSVNNLGNTTPDSQITSYRNNNIDLITARPHSVIYGTTAQQTLETNFNDHHDCNKSTEKHELIIPTPSKPLKKRKKRRQSKMYQHLQHLSRSKPLPLTPNSKYNGEASVQLGKTYTVIQDYEPRLTDEIRISLGEKVKILATHTDGWCLVEKCNTQKGSIHVSVDDKRYLNEDRGIVPGDCLQEYD
What is the function of this protein?
Interacts with SHO1.
What are the official names of this protein?
Nuclear fusion protein FUS1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUOD2_SALAI
Sequence: MTTDAELRELTVGTGAGGEQLGTDMVLNIGPQHPSTHGVLRLRLVLDGERVVSAEPIVGYMHRGAEKLFEVRDYRQIIVLANRHDWLSAFANELGVVLAVERLMGMEVPERATWLRMALAELNRVLNHLMFLGSYPLEIGAITPMFYAFRERETLQAVLEEVSGGRIHYMFNRVGGLKEEVPAGWTGRARTAIGEVRRRMPDLDRLIRRNEIFLARTVGVGVLSAAQAAAFGASGPVARASGLDLDLRRDEPYLAYDQLEVPVVTRTAGDCHSRFEVLLDQVYVSLDLAEQCLDQVDRLTGPVNTRLPKVLKAPEGHTYAWTENPLGINGYYLVSRGEKTPWRLKLRTASYANVQALATLLPGCLVPDLIAILGSMFFVVGDIDK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CHED_DESRM
Sequence: MELAKGNAEIQVGIADYKVAASPNRLITLGLGSCVGVVLYDPVKKVGGLLHIMLPDSTQFNNVTKPAKFADTGIPLMIDEIKRLGGIPSRLTAKLAGGAQMFSGLDEKFVLNIGQRNSKMVKEILSRMGIRILAEELGGNRGRTMIFDIASGQVTIRTIGSPLKVI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: PYRC_LACJO
Sequence: MTTVIKNGTVYQNGHLIKADVLIDGQKIKAIGTDLEGEEIIDASGMIVSPGLVDVHVHYRDPGQTYKEDIKTGSQAAARGGFTTVGAMPNVTPVPNTAELMDKMVRENQKKGLVHILQYGPVTNDETTDIIPDYAALKKAGAFALSNDGHGVQSAQTMYLAMQKAKENNLIIAAHAQDDSLFNKGIVNEGIAAEKLDLPPVTELAETTQIARDLLLAQKTGVHYHICHVSTKTSVELVRLAKARGIKVTCEVAPHHILLTDSDIPEDNAYFKMNPPLRSKEDQVALLVGLLDGTIDLIATDHAPHAKAEKQGGMRGAAFGITGSETAFSTLYTRFVKEEKVFTLEQLLSLLTDKPATVFGIENAGLLAPGENADIAIFDIEHQREIKEDDFKSKGVNTPFTGHKVYGETVMTFVDGKVVYQRGTK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: CYSH_MYCTU
Sequence: MSGETTRLTEPQLRELAARGAAELDGATATDMLRWTDETFGDIGGAGGGVSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIGTRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDVQEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTECGLHAS
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPH2_VACCA
Sequence: MEKNLPDIFFFPNCVNVFSYKYSQDEFSNMSKTERDSFSLAVFPVIKHRWHNAHVVKHKGIYKVSTEARGKKVSPPSLGKPAHINLTAKQYIYSEHTISFECYSFLKCITNTEINSFDEYILRGLLEAGNSLQIFSNSVGKRTDTIGVLGNKYPFSKIPLASLTPKAQREIFSAWISHRPVVLTGGTGVGKTSQVPKLLLWFNYLFGGFSTLDKITDFHERPVILSLPRIALVRLHSNTILKSLGFKVLDGSPISLRYGSIPEELINKQPKKYGIVFSTHKLSLTKLFSYGTLIIDEVHEHDQIGDIIIAVARKHHTKIDSMFLMTATLEDDRERLKVFLPNPAFIHIPGDTLFKISEVFIHNKINPSSRMAYIEEEKRNLVTAIQMYTPPDGSSGIVFVASVAQCHEYKSYLEKRLPYDMYIIHGKVLDIDEILEKVYSSPNVSIIISTPYLESSVTIRNVTHIYDMGRVFVPAPFGGSQEFISKSMRDQRKGRVGRVNPGTYVYFYDLSYMKSIQRIDSEFLHNYILYANKFNLTLPEDLFIIPTNLDILWRTKEYIDSFDISTETWNKLLSNYYMKMIEYAKLYVLSPILAEELDNFERTGELTSIVQEAILSLNLRIKILNFKHKDDDTYIHFCKILFGVYNGTNATIYYHRPLTGYMNMISDTIFVPVDNN
What is the function of this protein?
NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase.  Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm.  Required for replication and propagation of viral particles.
What are the official names of this protein?
RNA helicase NPH-II, Nucleoside triphosphatase II, NTPase II, Nucleoside triphosphate phosphohydrolase II, NPH II, RNA helicase I8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: SCA4_RICCN
Sequence: MSKDGNLDTSEFDPLANKEYTEEQKQTLEQEQKEFLSQTTTPALEADDGFIVTSASFAQSTPSMSALSGNISPDSQTSDPITKAVRETIIQPQKDNLIEQILKDLAALTDRDLAEQKRKEIEEEKEKDKTLSTFFGNPANREFIDKALENPELKKKLESIEIAGYKNVHNTFSAASGYPGGFKPVQWENHVSANDLRATVVKNDAGDELCTLNETTVKTKPFTLAKQDGTQVQISSYREIDFPIKLDKADGSMHLSMVALKADGTKPSKDKAVYFTAHYEEGPNGKPQLKEISSPKPLKFAGTGDDAIAYIEHGGEIYTLAVTRGKYKEMMKEVELNQGQSVDLSQAEDIIIGQGQSKEQPLITPQQTTSSSVEPPQYKQQVPPITPTNQPLQPETSQMPQSQQVNPNLLNTATALSGSMQDLLNYVNAGLTKAIDSNKQIDLIKEAATAILNNEKSDIAEKQANIIALAENTVNNKNLKPDAKVTGVNAVLETIKNDQNTPNLEKSKMLEATVAIVLNSENLEPKQKQQMLEKAVDVGLSLKDDASRAAAIDGIKDVVIKSNLSPEDKMLIAVGDKVNVSELSNAEKQKLLGSVLKKGVEAQVLSPAQQQLMQQHLYKIMAEQTKKDTIKKVNDILFDPLSNTELKTTNIQAITSNVLDGPATAEVKGEIIQAITNTIAGSSLEAQDKAAIIKGVGETIATHSDTSLSLPNKALIMASAEKGIAESQTNLPDRELMTKGLVDGIYEGKGGPEITKAVSSGIDNSNINDSEKEALKKAKDAASEAALDRDTQNLTEGFKGQNIEEHKPHDDIYNKAREVINAVNPVIEALEKSKEPVVSAEERIVQETSSILNNISKLAVEKVNNFRAMLSPNGNLKTLEEKKEEAIKKVDELVKAFGTKSSTEEQQSFIKTNLIDDKTLSKEVRLQTIDKLLQEQKRSEAIENPSVKTEDVRVVSGKSKLKPISKDNPDIEKAKMVVGRDRVNIKGNIKIMGALMNARDIIQSENLNKSTPIKRESSPPQR
What are the official names of this protein?
Antigenic heat-stable 120 kDa protein, 120 kDa antigen, Protein PS 120, PS120, RCA.
What are the subcellular locations of this protein?
Cytoplasm.