PharMolix/UniProtQA huggingface dataset:
Protein: TIPIN_RAT
Sequence: MLEQEENGLFEIPDYEHVEDETFPPFPPPGSPERDPAEAEPDEGSGAPVPVPPKRIVKRNIPKLDATRLTSERGLPALRHVFDKTKFKGKGHEAEDLKTLIRHMEHWAHRLFPKLQFEDFIDRVENLGNKKEVQTCLKRIRLDLPIVHEDFVNNNDEVEETNSLDAAATGFDAFVTSSSDSKRFASEASRNLTEEQQQRIEKNKQLALERRQAKLLSNSQSLENDVTVEESSTGENQEESNGLISADGPHDVPSASTQEEGQLEAEETQLDHPNLD
What is the function of this protein?
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.  Important for cell survival after DNA damage or replication stress.  May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.  Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.
What are the official names of this protein?
TIMELESS-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CSM3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLMM_PSYWF
Sequence: MSYFGTDGIRGLFGKFPITPDFVLKLGYVTGQVLVEQNPNPKKKPSVVIGKDTRLSGYVIEAALQAGFNSAGVDVHMIGPLPTPAIAHLTRSFHADAGVVISASHNPYYDNGIKFFAADGRKLSDEMQNAINDKLKTVVEGHADYTQDDPAQLGKHFRINDAKGRYIEFCKGSFPYQYDLSNLTVVIDCANGAGYSVGPRVLRELGANVIAIHNKPNGININDNCGSTHPETLQKAVLEHKADVGIALDGDGDRIIMVDEKGVVVDGDGILYILATKSEAKAEGVVGTQMSNMGLQLALEAAGIALERAKVGDRYVMQGLEAKGWILGGEPSGHILCLDKSRTGDAIIAGLQVLAVMAQTQKSLSQLTEGFKLLPQCLVNVRLEQMQDPYDFPELVAAFEAASKQIEGRGRILIRKSGTEPLIRVMVELDNAEECDKLAHELADKVKQVMA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: VGP_TAFVC
Sequence: MGASGILQLPRERFRKTSFFVWVIILFHKVFSIPLGVVHNNTLQVSDIDKFVCRDKLSSTSQLKSVGLNLEGNGVATDVPTATKRWGFRAGVPPKVVNYEAGEWAENCYNLAIKKVDGSECLPEAPEGVRDFPRCRYVHKVSGTGPCPGGLAFHKEGAFFLYDRLASTIIYRGTTFAEGVIAFLILPKARKDFFQSPPLHEPANMTTDPSSYYHTTTINYVVDNFGTNTTEFLFQVDHLTYVQLEARFTPQFLVLLNETIYSDNRRSNTTGKLIWKINPTVDTSMGEWAFWENKKNFTKTLSSEELSFVPVPETQNQVLDTTATVSPPISAHNHAGEDHKELVSEDSTPVVQMQNIKGKDTMPTTVTGVPTTTPSPFPINARNTDHTKSFIGLEGPQEDHSTTQPAKTTSQPTNSTESTTLNPTSEPSSRGTGPSSPTVPNTTESHAELGKTTPTTLPEQHTAASAIPRAVHPDELSGPGFLTNTIRGVTNLLTGSRRKRRDVTPNTQPKCNPNLHYWTALDEGAAIGLAWIPYFGPAAEGIYTEGIMENQNGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPQDWTKNITDKIDQIIHDFVDNNLPNQNDGSNWWTGWKQWVPAGIGITGVIIAIIALLCICKFML
What is the function of this protein?
GP2delta is part of the complex GP1,2delta released by host ADAM17 metalloprotease.  This secreted complex may play a role in the pathogenesis of the virus by efficiently blocking the neutralizing antibodies that would otherwise neutralize the virus surface glycoproteins GP1,2.  Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production.  GP1,2delta does not seem to be involved in activation of primary macrophages (By similarity).
What are the official names of this protein?
Envelope glycoprotein, GP1,2, GP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[GP2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In the cell, localizes to the plasma membrane lipid rafts, which probably represent the assembly and budding site. SUBCELLULAR LOCATION: [GP1]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=GP1 is not anchored to the viral envelope, but forms a disulfid-linked complex with the extravirion surface GP2. In the cell, both GP1 and GP2 localize to the plasma membrane lipid rafts, which probably represent the assembly and budding site. GP1 can also be shed after proteolytic processing. SUBCELLULAR LOCATION: [GP2-delta]: Secreted. Note=GP2-delta bound to GP1 (GP1,2- delta) is produced by proteolytic cleavage of GP1,2 by host ADAM17 and shed by the virus.
Protein: SF3BB_ARATH
Sequence: MQASDRFNINSQLEHLQAKYVGTGHADLSRFEWAVNIQRDSYASYIGHYPMLSYFAIAENESIGRERYNFMQKMLLPCGLPPEREEE
What are the official names of this protein?
Uncharacterized protein At4g14342.
What is the protein family that this protein belongs to?
Belongs to the SF3B5 family.
Protein: PONA_DICDI
Sequence: MLVLRNLLALVTLALLFTLSSAQYTLSVSNSASGSKCTTAVSAKLNACNTGCLNSFNIVESSNGKGLVFKTFINAACSGEYESLSQFTCAANQKIPTTSYIVSCNSTPSSNSTTDSDSSSGSTVMIGLASSLLFAFATLLALF
What is the function of this protein?
Binds F-actin and nucleates actin assembly.  Major high affinity link between the plasma membrane and the cortical actin network.
What are the official names of this protein?
Ponticulin.
What is the protein family that this protein belongs to?
Belongs to the ponticulin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor, GPI-anchor. Note=Preferentially localized in some actin-rich membrane structures. Must span the plasma membrane, probably via beta-strands.
Protein: LFG2_RAT
Sequence: MTQGKLSVANKAPGTEGQQQANGEKKDAPAVPSAPPSYEEATSGEGLKAGAFPQGPTAVPLHPSWAYVDPSSSSGYEGGFPAGHHELFSTFSWDDQKVRQLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTIFSFQTKFDFTSCHGVLFVLLMTLFFSGLLLAILLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE
What is the function of this protein?
Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis.  Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation.  Plays a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development (By similarity).
What are the official names of this protein?
Protein lifeguard 2, Fas apoptotic inhibitory molecule 2, Neural membrane protein 35.
What is the protein family that this protein belongs to?
Belongs to the BI1 family. LFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft. Postsynaptic cell membrane.
Protein: KCY_DESVH
Sequence: MPDTTGGHPAALKVVTLDGPAGVGKTTLARRVADALGIPYLDTGAMFRTMAWRLGPDGPDLDEALLRDRLAGFVFTLRGRGGASVLSCNGEDIGNEIRTEEVGAMASRIAALPVVRECLKAAQQRMGAAQPLVVEGRDMGTVVFPGARHKFFLDAAPEIRAMRRYTQLQTMGEAHDLALLTEQIRSRDEQDRNRAVAPLRPAADAIIVDTGDLDIDGVFGVIMQHIRSRDGL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P23A_BRANA
Sequence: MSRHPTVKWAQRSDWVYITVELPDAEDVKLKLEPEGKFFFSATSGASKTLYEVDLDLLDSVDVNESKASVSSRSVFYLVKKAESKWWNRLTKPEGKHPLYLKVDWDKWVDEDDEDKGGEGDMDFGDFDFNGLNMGDTDEIGEEVAEEDGDGEGETAAETKEKKIDGEKDEEGVNAKKD
What is the function of this protein?
Acts as a co-chaperone for HSP90.
What are the official names of this protein?
Co-chaperone protein p23-1, Bnp23-1.
What is the protein family that this protein belongs to?
Belongs to the p23/wos2 family.
Protein: URE2_BACSU
Sequence: MKPGAFQIAEGTITINEGREIREVTVKNTGSRSIQVGSHFHFAEANGALLFDRELAIGMRLDVPSGTSVRFEPGEQKTVSLVEIRGRKTIRGLNGMADTFIDERGKEKTLANLKQAGWMEGVIR
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_LACGA
Sequence: MAIIKYKPTTNGRRNMTSSDFAEITKKKPEKTLLESQSHTAGRNSYGHITVRHRGGGHKQKYRIIDFKRNKDDVKAVVKAIEYDPNRTANIALLHYTDGIKAYILAPKDLKVGTVVESGPNADIKPGNALPLSAIPAGTEIHNIELKPGKGGQLVRSAGTVAQVLGNDGKYTLVRLQSGEVRKILSTCRATIGSVGNEQHSLIQLGKAGRKRWLGKRPQSRGSVMNPNDHPHGGGEGKAPVGRPQPMTPWGKKSRGIKTRNSKARSEKLIIRHRKGNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: LACB_STAAM
Sequence: MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPIFGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGRIIGELLMCDIIDAFINAEYKATEENKKLIAKIKHLETSNADQADPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: SURE_LEGPL
Sequence: MKILVSNDDGVLAPGIKILANELSTLGEVKVVAPDRNRSGASNSLTLTQPLRVKQLDNGYYSVDGTPTDCVHLALTGFLEPMADIVVSGINEGANLGDDVLYSGTVAAAMEGRYLGLPAIAISMVGDNIQHYETAAIIAKQLVIKLSANKLPSQTILNVNVPDLPLNQIRGLQVTRLGTRHSAEPIIKEYDPRGRPIYWVGPPGIEADAGAGTDFFAIKTGHVSITPLHLDMTHYKLFDHLSNLLNEICIEN
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5977_ARATH
Sequence: MKMSSRIGLFKLLILLFFQIYSVYAFTDGSDFTALQALKNEWDTLSKSWKSSDPCGTEWVGITCNNDNRVVSISLTNRNLKGKLPTEISTLSELQTLDLTGNPELSGPLPANIGNLRKLTFLSLMGCAFNGPIPDSIGNLEQLTRLSLNLNKFSGTIPASMGRLSKLYWFDIADNQLEGKLPVSDGASLPGLDMLLQTGHFHFGNNKLSGEIPEKLFSSEMTLLHVLFDGNQFTGSIPESLGLVQNLTVLRLDRNRLSGDIPSSLNNLTNLQELHLSDNKFTGSLPNLTSLTSLYTLDVSNNPLALSPVPSWIPFLNSLSTLRLEDIQLDGPVPTSLFSPLQLQTVSLKHNLINTTLDLGTNYSKQLDFVDLRDNFITGYKSPANNPVNVMLADNQVCQDPANQLSGYCNAVQPNSTFSTLTKCGNHCGKGKEPNQGCHCVYPLTGVFTLRSPSFSGFSNNSNFLKFGESLMTFFKNGKYPVDSVAMRNISENPTDYHLLINLLIFPSGRDRFNQTEMDSINSAFTIQDYKPPPRFGPYIFVADQYKTFSDLEDSKTVSMKVIIGVVVGVVVLLLLLALAGIYALRQKKRAQRATDQMNPFAKWDAGKNEMDAPQLMGTKAFTFEELSKCTNNFSDANDVGGGGYGQVYKGTLPNGQVIAIKRAQQGSMQGAFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQMLVYEYIPNGSLRDGLSGKNGVKLDWTRRLKIALGSGKGLAYLHELADPPIIHRDVKSNNILLDEHLTAKVADFGLSKLVGDPEKAHVTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVMLELLTGKSPIDRGSYVVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLKGFEKYVDVALQCVEPEGVNRPTMSEVVQELESILRLVGLNPNADSATYEEASGDPYGRDSFEYTGVFPTPKP
What are the official names of this protein?
Probable leucine-rich repeat receptor-like protein kinase At5g49770.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: IKIP_HUMAN
Sequence: MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAWFVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEIAHISDMN
What is the function of this protein?
Target of p53/TP53 with pro-apoptotic function.
What are the official names of this protein?
Inhibitor of nuclear factor kappa-B kinase-interacting protein, I kappa-B kinase-interacting protein, IKBKB-interacting protein, IKK-interacting protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization.
Protein: PSBB_WHEAT
Sequence: MGLPWYRVHTVVLNDPGRLLAVHIMHTALVSGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITDSWGGWSISGGTVTNPGIWSYEGVAGTHIVFSGLCFLAAIWHWVYWDLEIFSDERTGKPSLDLPKIFGIHLFLAGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQAVNPAWGAEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSNGLAENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRDKEGRELFVRRMPTFFETFPVVLVDEEGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRSQLGEIFELDRATLKSDGVFRSSPRGWFTFGHATFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGTFQKVGDPTTRKQAA
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RSMF_AERHH
Sequence: MHDNTYLPDHFLRHIAAIMPAHLSMDEFVASCRRPLRRSIRVNTLKISVAAFVARMQPLGWQLDPVPWCDTGFWLSREDESVPLGNTAEHLSGLFYIQEASSMLPVTALFACEQTRRDGMLLDAAAAPGSKTTQIAALMNNQGMLVANEYSSSRLKVLSANLQRCGVTNVGMTHFDAKVFGQWLPETFDAILLDAPCSGEGSVRKDEDALRNWSIESIDEIAAVQQGLLESAFHALKPGGVLVYSTCTLSLQENQAVCQSLLDKFGAAFSFDSLADLFPAAEQACTPEGYLHVWPQIFDSEGFFVARLRKHYSVPNTMFKPGKLGKFPFLPLPAKESEPMLREIEAAFGVVPQGNLFGRSEEIWLFPQRFEQVQGKLRFDRIGLKLAETFKKGYRLTHEWALAYGDGASKGFVELGIADAREFMMGRDVWPEQAAGTGEVIVRYQGHTLGMGKWVGSRVKNALPRELVRDNNLFV
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMDH_HAEIN
Sequence: MSLRIKQEALTFDDVLLVPAHSTVLPNTANLSTQLTKEIRLNIPMLSAAMDTVTETKLAISLAQEGGIGFIHKNMTIERQADRVRKVKKFESGIVSEPVTVLPNLTLAELAEMVKKNGFAGYPVVDGENNLIGIITGRDTRFVKDLSKTVSQVMTKKEDLVTVKEGASREEILELMHQHRVEKVLVVNDSFKLKGMITVKDFQKAEQKPNACKDEFGRLRVGAAVGAGAGNEERIDALVKAGVDVLLIDSSHGHSEGVLQRVRETRAKYPNLPIVAGNVATAEGAIALADAGASAVKVGIGPGSICTTRIVTGVGVPQITAIADAAAALKDRGIPVIADGGIRFSGDIAKAIAAGASCVMVGSMFAGTEEAPGEIELYQGRAFKSYRGMGSLGAMAKGSSDRYFQSDNAADKLVPEGIEGRIPYKGYLKEIIHQQMGGLRSCMGLTGCATIDELRTKAEFVRISGAGIKESHVHDVAITKEAPNYRMG
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: RECA_DESVM
Sequence: MAKKPALTPEEMRREALSTALSTIERKYGQGSVMKLSDTAHVNIPVIPTGSIGLDLALGVGGIPRGRVSEIYGPESSGKTTLALHIIAECQKLGGTAAFIDAEHALDTNYARRLGVKTDELLISQPDFGEQALDIADMLVRSSAVDIVVIDSVAALIPQAELEGVMGEMQVGGQARLMSHALRKLTGTIHKSRTAVIFINQIRMKIGTMGYGNPETTTGGNALKFYSSIRMDIRKIQTLKDKEEVYGSRTRVKVVKNKVAPPFREALFDILYGTGISRTGELIDLGSDVGIIEKSGSWFAFGSERLGQGKENVRALLEENEALRLNVEAKLIEHLGMMPSKVVDPDDNAGAMDDDEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_COLGM
Sequence: MDAPATASRQPIAEEPRMSQESSLSTVSTTSLVFDRLHEHNEKSYHSSSQRRRAPSASRGGYADHPDDDDDDDESYKEADTNDLETGPFLAPASVMMRRVGVDRGLKKVILILAAAFLFAWGAALFVFLSNKSYKHASTIDHDPSATSRGSGKPVTLDQVISGFWYPTSHSISWIEGPNGEDGLLLEQGARGKDYLVVEDVRSGNKDSQVSANVVQSRTLMKNPWINVGGRQLAPSDTRPSKDMKKVLVSTDRQRNWRYSYTALYWIFDVETQTAEALDPEHPDGRVQLATWSPQSNAIVFTRDNNLFLRKLDGDKKVTQITNDGGPEYFYGIPDWVYEEEVFATNSATWYSEDGKYVAFLRTNETGVPEYPLQYFLSRPSGKEKPPGEETYPDEKRIKYPRAGSHNPVVDLLFFDVERGDVFSVDIDGGFADDDRLINMVLWANDKVLIKETNRVSDIMRVVLVDVVARTGKTVNTIDVGELDGGWFEISHTTQFIPADPANGRPQDGYIDTVVHGNGDHIAYFSPMDNAEPVYLTGGDWEVDDGPSAVDLKNNLVYFVATKESSIQRHVYSVHLNRSDLKPFTDTKFESYYDISFSSGAGYALLSYQGPKIPWQKVVSTPSSPVSYEHVVEKNEDLAENAKKYELPILNYGTLKVDGVELNYVERRPPHFDEKKKYPVLFQQYSGPGSQSVHKKFAVDFQSYVASALGYLVVTVDGRGTGFIGRKNRVLIRDHLGYWEAHDQIAAAQAWAAKKYVDPARIAIWGWSYGGFNTLKTLEMDAGRTFSYGMAVAPVTDWRFYDSIYTERYMRTPQLNPSGYDQTAVSNVSALAGNVRWLMMHGVGDDNVHYQNTLTLLDKLDLNGIENYDVHVFPDSDHGIYFHGANRIVYDKLSNWLINAFNGEWLKVAGAKPIVEPKARV
What is the function of this protein?
Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Probable dipeptidyl-aminopeptidase B, DPAP B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Note=Lysosome-like vacuoles.
Protein: RS2_PASMU
Sequence: MAQVSMRDMLQAGVHFGHQTRYWNPKMKPFIYGPRNGVHIINLEKTVPMFNEALVELTRIAGNNGKILFVGTKRAATEAVKAAALDCQQYYVNHRWLGGMLTNWKTVRQSIRRLKDLETQSQDGTFDKLTKKEALMRTREMEKLELSLGGIKEMGGLPDALFVIGADHEHIAVKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAARAIQLYLSAAAAAVKEGRHQDAVTEENFVAEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: AMPP1_PYRTT
Sequence: MLLPRIPQLSHATRAAYVAAKSPFSPVPVRPFHASAALRAIDMAKVDTTHRLAELRKLMKERNVDIYMVPSEDSHQSEYIAPCDARRAYISGFTGSAGYAVITHEKAALSTDGRYFNQAEKQLDSNWELLKQGIQDVPTIQQWTADQAGGGKVVGVDPSVVTAGDARKLAEKIKKKGGEYKAIDENLVDLVWGSERPARPSEKVIVQPKKYAGKGFEDKIDDLRKELEKKKSLGFVVSMLDEVAWLFNLRGSDIPYNPVFFSYAVVTPTTATLYVDENKLPEDVKEHLGDKITIRPYEAIFGDVTALSKELFEANDKNETQKKFLTSNTASWALNKALGGDDKVEETRSPVGDSKAVKNEVELEGMRQCHIRDGAALSEYFAWLEDQLINKKATLDEVDGADKLEEIRKKHDMFMGLSFDTISSTGANAAVIHYKPEKGECATIDSKAIYLCDSGAQYRDGTTDTTRTLHFTEPTEMERKAYTLVLKGNMALERVKFPKGTTGFALDALARQFLWAEGLDYRHGTGHGVGSFLNVHEGPIGIGTRVQYSEVSLAVGNVVSDEPGYYEDGKFGIRIENMVMVKEVETKHKFGDKPYLGFEHVTMTPYCRNLVDMKLLTEDEKKFINDYHKEVYEKTSKYFDKDALTLEWLKRETAPY
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: GEP7_YEAS2
Sequence: MVLSNVKIFRLKSHRAFRIGPMIKAVAGNLLVKRFYQPKLERIPPASLLLKQKIRLAQNGSTTSTENPISFSQTMSEIFSVLQPSAPDLDEDKTSGLKRDHLLTERLNNGELGVIMNKFFNPSSTHNNQLIDTNILLQNFPKLSGNDLDLLDFAINEKMRGNWNDLKQDFIQLWYYKSFGFLGPRTQFVLTNSSPSLRSQFLKLPFTEYNWFLLQNNKNANILPADVQNVVKVFHLDDKRFTWKSIDPFSKAIISFVVFVSIYVWLDESAKQKTKDLPAQKSTVISE
What is the function of this protein?
Involved in respiratory growth and required for cell survival in the absence of prohibitins or GEM1.
What are the official names of this protein?
Genetic interactor of prohibitin 7, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GEP7 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: EI3D2_DROVI
Sequence: MSQYAPFIKPYIEYNQFGWGPCDMPDMEVPYQPFCKSDRLGKISDWMMPVQEKKYANKYASTFGSNNSQYAYFHEDDDATFHLVDGGNPRALKPYQRNRYRPNQRNNVRVHGRNVRGNAAIGGGQGGAGGTGGAGVGNKYGKGRDMRRGNMGRRFMRNAPVRLRESSVVVRSDWVSIEEIDFPRLLKLSLPNIKDGVDVVTCGTLEYYDKQCDRINVKNERPLQKIDRIINVPGTIDDPIIRRLSKSMGNVFATDDIIATLMCCTRSNYSWDIVIEKLGTKVFLDKRDNAQFDLLTVNETALEPPQDEEGSINSPQSLSLEATLINHNFSQQVLKIGEQEPKHKFDEPNPFEEPGVELASVAYRYKEWQLGDDVVLIARCKHNGVIKSPAGELQFLSIKALNEWDSKAANSVEWRQKLDSQRGAVLASELRNNACKLAKWTVEAVLAGSDQLKLGYVSRVNRKDHLRHVILGMQQFKPQEFATQINLNMDNAWGVLRCLVDIVLKQPDGKYLIMKDPNKPMIRLYDIPDNAFDSDGNDDEETSDDRPFLKSLGN
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-2, eIF3d-2, Eukaryotic translation initiation factor 3 subunit 7-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_METRJ
Sequence: MATPSLDSARAADAAIEKAPDLLPEALPGRRPSLVGLTRDALKAQLIGMGVPERESRMRAGQVWHWVNFRGASDFAEMTNVGKALKAQLAEHFTLERPEVASRQVSRDGTRKWLLRMAPTNRQEHNRGAEIECVYIPGPDRGTLCVSSQVGCTLTCSFCHTGTQRLVRNLSAAEIVQQLVTARDELGDWPGQMPSRDAGGSGEVGRLVTNIVFMGMGEPLYNLDAVVDAVGVMSDQEGLGLSRRRITVSTSGVVPQIPRLGEQANAMLAISLHAVRDDLRDELVPLNRKYPIAELLAACRAYPGLSNARRITFEYVMLKGVNDSDADARELVRLLKGIPAKINLIPFNPWPGSRYECSDWDRIERFSEIVFNAGYASPVRTPRGRDILAACGQLKSETEKLRARARLMQEEGIGVESFYAGADD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAT1_MAGO7
Sequence: MAESDLWSVDANSALELSLVEPTEDGLTTVTRFHPRFTYPLFGEEEQIFGYQDLKINLQYHAPDMRPNVKITHSKKFKSIGETQPTDLDALLQGYLPPVAFAKKREFEDAIRLMPADWTPPGEILSEFDGVDGAKFEIRRSNLADDASRQIIDRVQLLILLFIEGGSYIGTDTTDSLDRWDIFFLYNIKPSTTDGTSRYQFAGYSTVYKFFPLQRFPLEPKEAHENLELPSGEFPFSNLRSRTRISQFLILPPFQKSGNGSRLYRTIYDYCLRDPNVIEVTVEDPNEAFDDMRDVADLDFLRQKSEFTDLRINTDIHIPKQGAAPRGVVDEVKSEEARCLYRIAPRQFSRVLEMHLMSRLAETVRPTLVDDKVVAKPTKIETHEYDLWKLFVKQRLYRHNKEVLSQLDRHDRIERLNETLGSVELEYARILALAERRTQATSSNLKRKLDDDENTEGSSSKKARVEDA
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG (By similarity).  Involved in DNA double-strand break repair (PubMed:30776962).  Required for appressorium turgor pressure, autophagy and conidial nuclear degradation (PubMed:30776962).  During the germination process and upon starvation conditions, translocates from the nucleus to the cytoplasm where it acetylates ATG3 at 'lys-262' and 'Lys-267', thus influencing autophagy through controlling ATG3-ATG8 interaction (PubMed:30776962).  Also acetylates ATG9 at 'Lys-621' to regulate ATG9 binding to vesicles, which is also important for autophagy and pathogenicity (PubMed:30776962).
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Preautophagosomal structure. Note=Is only present in the nucleus under nutrient-rich condition, and translocates from the nucleus to the cytoplasm with the assistance of SSB1 during germination or upon starvation.