PharMolix/UniProtQA huggingface dataset:
Protein: RFS_RHIO9
Sequence: MPVASSEYQNEHYASFATTSRLVTCLVSETLVPVFFVPVKSVDRNNQFIGLCLLLRPTTVKQESELPTNITASDILTVVPLRGLPILNNERVALFNGIRCPQIDLVDFLDMLPHIYSVESSGSLKSGDSLKQKTFDTLSAILDGNKTFDLVDGYSAVQLWNHFAQDLEINSKLREQIGQELGSSILFQKYTYDNPKPLPTLNSSTIKWEQSVVEGHATHPMHKARKSFPPMPPLNPGSYDLDHPAVRLVGIPRENAILRGEYEELSAPLVNALMDAGGNHKDIRAQYQNYVFIAIHELQLPNIQEKFKDAVIFSKEHQLNVEALASLRSVARPDILPGLSVKLCLGIKISSALRTVTPFTTYFGPGFSFNVVPKLTYDHEVLAIERELGTITYRHEDSDVAKHCSSVIREALEYDPKYQDDLFIPCGALVEKIQRPDTDETLVAHVWNLDTKEKRVEFLDRYVDFALRSFLPPCLINGVAFEAHGQNTLARFDRKTGLLKGFVIRDFGGVKAHNETLKKSAGVELDILPDSCVEAHSLEEVFKLLYHTLFHCQLQRLIRVLDLHYSGEGWEIVRKYLTQYVPKDHVMWPMFMESSKVPGKCLVRMKIDELYRDYIYRPVPNMIKYEPQSVPEAI
What is the function of this protein?
NRPS-independent siderophore synthetase that catalyzes the rhizoferrin biosynthesis from citrate and diaminobutane via an ATP-dependent condensation of citrate with diaminobutane followed by the addition of a second citrate to the monocitryl-diaminobutane intermediate (PubMed:28610916).  Can also use as substrates the citrate and diaminobutane homologs oxaloacetic acid, diaminopropane, diaminobutane, diaminopentane, tricarballylic acid, hydroxylamine and ornithine (PubMed:28610916).  Forms only a mono-substituted intermediate with oxaloacetic acid and diaminopentane whereas both mono-citryl intermediates and full rhizoferrin derivatives were detected when diaminopropane, and ornithine were used as substrates (PubMed:28610916).  Tricarballylic acid only forms a rhizoferrin derivative, but no mono-substituted intermediate (PubMed:28610916).
What are the official names of this protein?
NRPS-independent siderophore synthetase rfs, NIS rfs, Rhizoferrin biosynthesis protein rfs.
Protein: NORW_ESCF3
Sequence: MSNGIVIIGSGFAARQLVKNIRKQDTGIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDKLVLATGANAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTNSGILATLDRQRSTEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRRDLRWQICTESQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_SALEP
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDALNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDLEQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAGGEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLGLLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLAEMGIILEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS51_METMP
Sequence: MIAIIDYNAGNLRSIEKALELYTKNIVVTSDPETILSADKLVLPGVGNFGDSMKNISQKTGDCSLNEIINKCVQKVPFLGICLGMQLLLEKSEECPETPGLGVIKGDVIKFKHSEKIPHMGWNTVNQVQDIPLFEGIANNEYFYFVHSYHVNPSEKDVISGTTNYGYEFPCILNKKNVYATQFHPEKSGKNGLKMIENFVELI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 1, IGP synthase glutaminase subunit 1, IGP synthase subunit HisH 1, ImGP synthase subunit HisH 1, IGPS subunit HisH 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THS1_VITVI
Sequence: MASVEEFRNAQRAKGPATILAIGTATPDHCVYQSDYADYYFRVTKSEHMTELKKKFNRICDKSMIKKRYIHLTEEMLEEHPNIGAYMAPSLNIRQEIITAEVPRLGRDAALKALKEWGQPKSKITHLVFCTTSGVEMPGADYKLANLLGLETSVRRVMLYHQGCYAGGTVLRTAKDLAENNAGARVLVVCSEITVVTFRGPSEDALDSLVGQALFGDGSSAVIVGSDPDVSIERPLFQLVSAAQTFIPNSAGAIAGNLREVGLTFHLWPNVPTLISENIEKCLTQAFDPLGISDWNSLFWIAHPGGPAILDAVEAKLNLEKKKLEATRHVLSEYGNMSSACVLFILDEMRKKSLKGEKATTGEGLDWGVLFGFGPGLTIETVVLHSVPTVTN
What is the function of this protein?
Mediates resistance to pathogens which are sensitive to stilbenes such as Botrytis cinerea, Eutypa lata and Plasmopora viticola by enhancing the production of phytoalexins.  Confers resistance to Phytophthora palmivora when expressed in papaya.
What are the official names of this protein?
Stilbene synthase 1, PSV25, Resveratrol synthase 1, Trihydroxystilbene synthase 1, StSy 1, Vitis stilbene synthase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL332_RHOJR
Sequence: MAARNEIRPIVKLKSTAGTGYTYVTRKNRRNDPDRLVMKKYDPVGRKHVDFREEK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: KIT_BOVIN
Sequence: MRGARGAWDFLFVLLLLLLVQTGSSQPSVSPGELSLPSIHPAKSELIVSVGDEIRLLCTDPGFVKWTFEILGQLSEKTNPEWITEKAEATNTGNYTCTNKGGLSSSIYVFVRDPEKLFLIDLPLYGKEENDTLVRCPLTDPEVTNYSLTGCEGKPLPKDLTFVADPKAGITIRNVKREYHRLCLHCSANQRGKSMLSKKFTLKVRAAIKAVPVVSVSKTSYLLREGEEFAVTCLIKDVSSSVDSMWIKENSQQTKAQTKKNSWHQGDFSYLRQERLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMMNTTVFVNDGENVDLVVEYEAYPKPVHRQWIYMNRTSTDKWDDYPKSENESNIRYVNELHLTRLKGTEGGTYTFHVSNSDVNSSVTFNVYVNTKPEILTHDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSVPVGPVDVQIQNSSVSPFGKLVVYSTIDDSTFKHNGTVECRAYNDVGKSSASFNFAFKGNSKEQIHAHTLFTPLLIGFVIAAGLMCIFVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEVALYKNLLHSKESSCNDSTNEYMDMKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPHRENPAVDHSVRINSVGSSASSTQPLLVHEDV
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.  In response to KITLG/SCF binding, KIT can activate several signaling pathways.  Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL.  Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase.  Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1.  Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B.  Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.  KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor.  Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.  Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1 (By similarity).
What are the official names of this protein?
Mast/stem cell growth factor receptor Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: DCD_GEMAT
Sequence: MGLCSDRWITRMSREHGMIEPFEDRQVRQGVISYGVSSYGYDMRVAREFKIFTNVLSSVVDPKAFDPKSFVEFEGDVCIVPPNSFALARSVEYFRIPRNVLTLTVGKSTYARCGIITNVTPFEPEWEGYVTLEISNTTPLPAKIYANEGIAQVVFFTGDEPPEVSYGDKKGKYQGQHGVTLPRI
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CODY_STAAW
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHSEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_YERPG
Sequence: MDQKFAVFGNPISHSKSPRIHTLFSEQTGIEHRYGKVLAPSEAFENTLVSFFADGAQGANITTPFKERAYDQCDELTDRASLAGAVNTIKRLEDGRLLGDNTDGIGLLSDLERQNLIRTTDHILLVGAGGAARGVILPLLSYGCTVVVTNRTHTRAQQLAKVFNHIGDIDVCEMSELAGQRFDLVINATASGLHGEVPNLPAAILTSQTRCYDMFYQAGTTPFLAWAQRLGLADYADGLGMLVGQAAHAFKLWHGVMPEITPVLAQLRSELGK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RL29_SHESH
Sequence: MKASELTEKSVEELNAELLGLLREQFNLRMQHATGQLTQTHQLKIVRRNIARVKTIITSKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y855_SULIN
Sequence: MIQGDLVQIQELNNEIGRFLIEIARKAIKEEFKLDKLDLSNYNNPILDKKGLAFVTLEKITYNTSSLRGCIGYVEAVAPLKQIVASAAKAAAFSDPRFNPLQKDELSEIIIEVTVLTKPEEIKVKDRWDLPKIIKVGEDGLIVEKGILHSGLLLPQVPMEYCWDEETFLAETCIKASLEPDCWLDNSVRIKRFHGIIFRETRPDGSDIIVVKPSDIKCKLNELLNNF
What are the official names of this protein?
Protein YN1551_0855.
Protein: RLMG_SALA4
Sequence: MSHVDDGFRSLTLKRFPQTDDVNPLLAWEAADEYLLQQLDETEIRGPVLILNDTFGALSCALAEHSPYSIGDSYLSELGTRENLRHNGIAESSVTFLDSTADYPQAPGVVLIKVPKTLALLEQQLRALRKVVTAQTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFSHPQLADAPQTLSWKLEDTGWTIHNHANVFSRTGLDIGARFFMQHLPENLDGEIVDLGCGNGVIGLSLLAKNPQAKVVFVDESPMAVDSSRLNVETNLPEAFERCEFMINNALSGVEPFRFNAVFCNPPFHQKHALTDNIAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCATIATNNKFVILKAVKQGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_VIBVY
Sequence: MPVVKVRENEPFDVALRRFKRSCEKAGILSEVRRREHYEKPTTVRKRAKAAAQKRHAKKLARENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RS19_PSEAE
Sequence: MPRSLKKGPFIDLHLLKKVEVAVEKNDRKPIKTWSRRSMILPHMVGLTIAVHNGRQHVPVLVNEDMVGHKLGEFAATRTYRGHAADKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: XDH_CAUVC
Sequence: MSSAIYPSLKGKRVVITGGGSGIGAGLTAGFARQGAEVIFLDIADEDSRALEAELAGSPIPPVYKRCDLMNLEAIKAVFAEIGDVDVLVNNAGNDDRHKLADVTGAYWDERINVNLRHMLFCTQAVAPGMKKRGGGAVINFGSISWHLGLEDLVLYETAKAGIEGMTRALARELGPDDIRVTCVVPGNVKTKRQEKWYTPEGEAQIVAAQCLKGRIVPENVAALVLFLASDDASLCTGHEYWIDAGWR
What is the function of this protein?
Involved in the degradation of D-xylose (PubMed:22709678, PubMed:25073011).  Catalyzes the initial reaction in the xylose utilization pathway by oxydizing D-xylose into D-xylonolactone (PubMed:22709678, PubMed:25073011).  Shows some activity with L-arabinose and D-lyxose, but D-xylose is clearly the best substrate (PubMed:22709678).  Has no activity with D-ribose, D-glucose, D-galactose or D-mannose (PubMed:22709678).
What are the official names of this protein?
D-xylose 1-dehydrogenase, XDH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TEMPT_APLCA
Sequence: MEQKRTLRVFLAVSLLCALANAYPQYQAVIPNGSSVPNPCNTSQIAQGVGHINFQGTGPLNPFGEDFKAAGKQWTTDLCDMDSDGDGRSNGVELGDPECVWSQGETPARTTDLSHPGFDEATVSC
What is the function of this protein?
A component of the complex of water-borne protein pheromones that stimulates attraction and mating behavior.  Modulates pheromone signaling by direct binding to attractin.
What are the official names of this protein?
Temptin.
What are the subcellular locations of this protein?
Secreted.
Protein: Y966_HAEIN
Sequence: MKLIATLGMAALLSGCSMFDSQQSAIPAEFAGADYQLSDQHAKQWAIASKQVEQCVYPNLTRILQQHFSKEDSYIHSQYVFFYPLEKIIGEQYVKIIQADEKSMNYASYQFKKFRTRVSNVEPLTKQSCLKLRNEARDDLAAVKGQYKNGMVEVQKNEDGTPKNSDGIATNQNKFFFDIIKWGSMLLL
What are the official names of this protein?
Uncharacterized protein HI_0966.
Protein: ALLS_MANSE
Sequence: QVRFRQCYFNPISCF
What is the function of this protein?
Strongly inhibits juvenile hormone biosynthesis in vitro by the corpora allata from fifth-stadium larvae and adult females.
What are the official names of this protein?
Allatostatin, Mas-AS.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PFF1_PARBA
Sequence: MSPAMANPRVRKFNPIAFTPLPVTLITTIVYLAVLILVLVTYLVVPPAPTLEMSPRGVNLTEAWRDLQHLTGGFHPYNSRRNDDVHAWLLHRIEAIVREHSAAADDVPEVFVFDDNLSNLTYSNGGVSKSPIVGVYFESTNIIVYIRGSEDDPQNWWEWSNGKPKGKGGVLVNAHYDSVSTGYGATDDGMGVVSLLQLLRYFTIAGNKPRKGLVLLFNNGEEDYLNGARVYSQHAMSNFTHTFLNLEGAGAGGRACLFRTTDTEVTRFYKNAKHPFGSVLAGDGFKLGLIRSQTDYVVFNGVLGLRGLDVSFIAPRSRYHTDQDDARHTNVDSLWHMLSVAIATTEGLVSYTGTDFDSKTTDQDKVNSGDGTLGVWFDIFGSAFAVFRLHTLFALSVTLLVSAPLVLFITSIALSKTDRMYLFSMSKSLGGTSETVSLRGLRGLFRTPIILTVTTVITIGLAYLLEKINPYIVHSSQFAVWSMMLSVWIFVAWFLARVADFFRPSALHRAYSYTWIFIATWIMLVISTVYANQKGIAAGYFIFFYFAAVFLATWVSYLELFSLPRKGYYAHQTSRGQRRRSSSLSSRLLTPSADELPSDIGPNGAENLGDPDETDPTESTSLLRGQRTTFANYRTGGNSGVTEYTAEGEHVREAGIFGHEQSWSWTLPRWTWILQLLLLAPIVIILVGQVGLLLTTAMSQIGSDGVSTFIVYLACALLSTLLFAPLFPFIHRFTYHVPTFLLLIFIGTLIYNLVAFPFSPANRLKIFFIQEVNLDDGTNKVSLTGIQPYLTNTINAIPSAAGQTANCTQGPFGSLVRCSWSGPPPRVVKEDPGNDQTMGPYTWISYNITKTVGKNEARIKVSGRNTRACKLKFDNPVADYRISGSAVDHRLPHTSRQGVAEIRLWSRTWENTWVVDVDWHSNPVKPGESKDGDEKQDVSKNELSGKVICLWSDNNESGVIPALDEVRLYAPAWVAISKSADGLVEASHDFIIQ
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RLMH_ENT38
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELVEIPAGKRGKNADIKRILDKEGELMLAAAGKNRIVTLDIPGKPWDTPQLAQELERWKLDGRDVSLLIGGPEGLSSACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_SYNPW
Sequence: MSAASLKVTTTSRPGSRLAVEVAVPAERSQASYEEAITRLSRSVNLPGFRKGKVPRTVLVQQLGALRIRATALESLVESVWRDALAQETIEALGQPELSGSFEELLDTFKPGEALTVTMETDVAPSPTLKSTKGLKAEAETVAFDAAKVDEMLEQSRRQLATVVPVEGRKAEQGDIAVVGFKGTYSDDGSEIEGGSADSMDVDLEHGRMIPGFVEGVVGMAVGDSKTVDCTFPEDYPKEDARGRKASFAIELKDLKTRELPELDDAFAKQASEQETLAELRSDLEQRLKDDAERRSRSNRHDALLAALVEQLEVELPESLIQQEVRNLVEQTAGQFAQQGMDVQSLFTPELVRNLMESSRPEAEERLRRSLALTALAESEKLSVDDADLNAKLKEVKGQLSGERDIDPERLRQAVLDDLLQEKLLGWLEENSTVTEKAPEAESDAAKASKPAAAKKDASKAKTAKTSKAKTAKAESESAES
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RSMH_NOSP7
Sequence: MKSDLETPLNLEELAFSHISVLGREVIEGLAVRPGGHYLDVTVGGGGHSRLILEAAADVRVTAVDQDEDALVAANKNLAEYSDRIQFIYSNFADYEFPPNTFDGILADLGVSSYHLDQAERGFSFRQAANLDMRMDRGRSLTAADVINNWDEAELADIFFKYGEERLSRRIARRIVERRPLHTTTELADAIASSVPPKYRYGRIHPATRVFQALRIVVNDELKSLETFLDKAPNALVPGGRIAIISFHSLEDRPVKHGLRNSPLLKVLTKKPIIAQEEEISNNPRSRSAKLRIAEKLV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLF_MOUSE
Sequence: MEKMSRQLPLNPTFIPPPYGVLRSLLENPLKLPLHPEDAFSKEKDKGKKLDDESSSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSTAPSVMDLSSRATAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL
What are the official names of this protein?
Hepatic leukemia factor.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. PAR subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: USO1_DROME
Sequence: MEFLKSGIKTVLGSTEPGQQPSAAETVEKLVDRVYSSTLLEDRRDACRALKALSRKYRIEVGAQGMPPLVQVLQNDGQDAEIISYALDTLCNVVTSEEFDEEADNPTVSVNVGEQFTEMFIKTPEHVTLVMGYLDEYDFRVRRAAIQLITSLISNKTRELQDLILVSPMGVSKLMDLLTDSREVIRNDVLLLLIELTKGNSNIQKIVAFENAFDRLFEIVREEGCSDGGIVVEDCLILLLNLLKNNSSNQQFFKEGSYIQRLSPMFELSQDAEEVGWSPQKVSNFHCLLQVVRALVTPSNQQQVVAACQRVMQKSRLLHALCEILMSSGVPADILTETINAVAEVVRGDRDNQDELGRVMAPSSPPRPAIVVLLMSMINEKQLLALRCAVLYCFECFLYRNADGQRAVVQTLLPSSASDVSALSTGQLLCTGLFSTDALANWFSAVALMHSLVENVALKEELLRVLLATPGGQKPITLLEQCTNLMQQERYRLQSKVGLLMLLSLWLAHCPGAVKALLETQGTMAYLTAQLCSNEHDEREFLVQGMCAFLMGLCIQFNDNSLPGQKREDISQLIIKRIGQESFCSKLAEVSRHEAYSRACKQAQIRAKSAGELLLDFEYCKLYKGLEALIAKLVSGFDVDGIELTELTLSSEASALVSQYKGIIRGMDAQIQALQQSSKELEQENAELKEKLGEEQSLKAQLLDQNTLLKAQLGASTGQVQSAQGAEATPPNEEELNAARYQANMYFAENIRLTKELETLRQQLSAEKQSADAAQDSLAAMQKDQEDLLELLADQEAKLTRYEEAGSTNTLPTSNVAPSVPAAGGGSPIPSGTASR
What is the function of this protein?
Essential for maintaining the architecture of the Golgi stacks and for normal organization of the transitional endoplasmic reticulum (tER).  Required for both the formation of the Golgi stacks and the maintenance of the individual cisternae.
What are the official names of this protein?
General vesicular transport factor p115.
What is the protein family that this protein belongs to?
Belongs to the VDP/USO1/EDE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, Golgi stack. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Associates with the tER membrane (PubMed:12876273). Localizes in developing Golgi stacks (PubMed:11514618).
Protein: GUAA_AERS4
Sequence: MTKDIHQHRILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPSGIILSGGPESVTEAGSPRAPEYVFNAGVPVFGICYGMQTMAEQLGGKVQSSTEREFGYAQVEVLGQTNALLRSIEDAIAPNGNALLDVWMSHGDKVTAIPADFTTIAQTATCPHAAMACESKHFYGVQFHPEVTHTRQGARMLEHFVKDICGCECLWTPATIIDDAVARIREQVGDDEVILGLSGGVDSSVVAMLVHRAIGDRLTCVFVDNGLLRLNEGEQVMEMFGDHFGLNIIKVEAEERFLSALAGEDEPEAKRKIIGRVFVEVFDDEAKKLKNARWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGMPAEMKMGLVEPLRELFKDEVRRVGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDILRRADAVFIEELRKADLYNQVSQAFAVFLPVRSVGVMGDGRKYDWVIALRAVETIDFMTAHWAHLPYDFLGHVSNRIINEINGISRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: HOA3_CUPNH
Sequence: MVQHITLHDMTLRDGMHPKRHQISLEQMKDIARGLDAAGVPLIEVTHGDGLGGASVNYGFPAHSDEEYLRAVLGELKQARVSALLLPGIGTVDHLRMAHEIGVHTIRVATHCTEADVSEQHIGMARKLGMDTVGFLMMAHMAPVQTLVQQALLMESYGANCLYITDSAGHMLPHDVTEKLGAVRQALRPETELGFHGHHNLAMGVANSLAAIACGASRIDAAAAGLGAGAGNTPMEVLVAVCERMGIETGVDVYRIADVAEDLVVPIMDHPIRIDRDALTLGYAGVYSSFLLFAKRAEAKYRIPAREILVELGRQRLVGGQEDMIEDTAITLARERGLLVP
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 3, HOA 3, 4-hydroxy-2-keto-pentanoic acid aldolase 3, 4-hydroxy-2-oxopentanoate aldolase 3.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: F10A1_CHICK
Sequence: MDSRKLGELRAFVRLCKQNPGLLHTEELGFLREWVESMGGTIPPAPASTSTDETSKGKAEEQPEEPVKSPEPESEESDLEIDNEGVIEPDNDDPQEMGDENVEVTEEMMDQANEKKMEAINALSEGDLQKAVNLFTDAIKLNPCLAILYAKRASVFVKLQKPNAAIRDCDRAIKINPDSAQTYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEKEIKERMERVKKAREEHERAQREEEARRQAGGAQFGGFPGGFPGGFPGAMPGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMAAFQDVAQNPANMSKYQNNPKVMSLITKLSAKFGSKP
What is the function of this protein?
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40.  Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein.  Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity).
What are the official names of this protein?
Hsc70-interacting protein, Hip, Protein FAM10A1, Protein ST13 homolog.
What is the protein family that this protein belongs to?
Belongs to the FAM10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSC7_SCHPO
Sequence: MDSTAGSDASTPTNHTVSSKKRRGRPPKGSYAAYGSSDDDDEEYSGRTRRRNRNTRPRVSAPSSSSTVVPKDLYSHRATLEDDELNFGVVDPEGEKKVNELGYLNGGREYRCRTFTCLGRGNRLYMLSTEPARAMGYRDSYLLFLKHRSLHKIIVDDSEKWDLIERNIIPHSYKGRAVGIVAARSIFREFGARIIVGGRRIVDDYWEGEFRARGFVEGELADPDDKLPPPGMPYNRNQYVAWHGASAVYHPQPSLEAQLPAAARKRKKEPPKDATWLFQHAKATAAYNNDITKYLVQKQDIGYFEPHTNLLHVPLNTQPTKTHWIQAKTGTECPAPKLDILVALNSDVAPQVSIANIPPSVYASCPLHVQEAIRKRQEQEIRSIRLNSMY
What is the function of this protein?
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  Controls particularly membrane and organelle development genes.
What are the official names of this protein?
Chromatin structure-remodeling complex subunit rsc7, Remodel the structure of chromatin complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the RSC7/SWP82 family. RSC7 subfamily.
What are the subcellular locations of this protein?
Nucleus.