PharMolix/UniProtQA huggingface dataset:
Protein: 3HAO_CHAGB
Sequence: MIGPPVNLPKWLEENSHLLKPPINNYCVYNGDFTVMIVGGPNARTDYHINTTPEWFYQHRGAMTLKIVDPTEGNNTFRDIVIREGDMFLLPANTPHNPVRFADTVGIVLEQKRPAGSLDRMRWYCQREGCGAVVKEAAFHCTDLGTQIKEAVEAFKADEEGRRCKQCGEVAEWCPKPGSIRDPNLE
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD, Biosynthesis of nicotinic acid protein 1.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLS_JAEV1
Sequence: MTKKPGGPGKNRAINMLKRGLPRVFPLVGVKRVVMSLLDGRGPVRFVLALITFFKFTALAPTKALLGRWKAVEKSVAMKHLTSFKRELGTLIDAVNKRGRKQNKRGGNEGSIMWLASLAVVIACAGAMKLSNFQGKLLMTINNTDIADVIVIPTSKGENRCWVRAIDVGYMCEDTITYECPKLTMGNDPEDVDCWCDNQEVYVQYGRCTRTRHSKRSRRSVSVQTHGESSLVNKKEAWLDSTKATRYLMKTENWIIRNPGYAFLAAVLGWMLGSNNGQRVVFTILLLLVAPAYSFNCLGMGNRDFIEGASGATWVDLVLEGDSCLTIMANDKPTLDVRMINIEASQLAEVRSYCYHASVTDISTVARCPTTGEAHNEKRADSSYVCKQGFTDRGWGNGCGLFGKGSIDTCAKFSCTSKAIGRTIQPENIKYEVGIFVHGTTTSENHGNYSAQVGASQAAKFTVTPNAPSITLKLGDYGEVTLDCEPRSGLNTEAFYVMTVGSKSFLVHREWFHDLALPWTSPSSTAWRNRELLMEFEGAHATKQSVVALGSQEGGLHQALAGAIVVEYSSSVKLTSGHLKCRLKMDKLALKGTTYGMCTEKFSFAKNPVDTGHGTVVIELSYSGSDGPCKIPIVSVASLNDMTPVGRLVTVNPFVATSSANSKVLVEMEPPFGDSYIVVGRGDKQINHHWHKAGSTLGKAFSTTLKGAQRLAALGDTAWDFGSIGGVFNSIGRAVHQVFGGAFRTLFGGMSWITQGLMGALLLWMGVNARDRSIALAFLATGGVLVFLATNVHADTGCAIDITRKEMRCGSGIFVHNDVEAWVDRYKYLPETPRSLAKIVHKAHKEGVCGVRSVTRLEHQMWEAVRDELNVLLKENAVDLSVVVNKPVGRYRSAPKRLSMTQEKFEMGWKAWGKSILFAPELANSTFVVDGPETKECPDEHRAWNSMQIEDFGFGITSTRVWLKIREESTDECDGAIIGTAVKGHVAVHSDLSYWIESRYNDTWKLERAVFGEVKSCTWPETHTLWGDDVEESELIIPHTIAGPKSKHNRREGYKTQNQGPWDENGIVLDFDYCPGTKVTITEDCSKRGPSVRTTTDSGKLITDWCCRSCSLPPLRFRTENGCWYGMEIRPVMHDETTLVRSQVDAFKGEMVDPFSAGPSGDVSGHPGSPSQEVDGQIDHSCGFGGPTCADAWGYHLH
What is the function of this protein?
May play a role in neuroinvasiveness.
What are the official names of this protein?
Structural polyprotein.
What are the subcellular locations of this protein?
[Peptide pr]: Secreted. SUBCELLULAR LOCATION: [Small envelope protein M]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Note=ER membrane retention is mediated by the transmembrane domains. SUBCELLULAR LOCATION: [Envelope protein E]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Note=ER membrane retention is mediated by the transmembrane domains. SUBCELLULAR LOCATION: [Non-structural protein 1']: Secreted. Host endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Note=Located in RE-derived vesicles hosting the replication complex.
Protein: YNCC_BACSU
Sequence: MDMNEHRNRRLKLIMISATFGGLLFGYDTGVINGALPFMARPDQLDLTPVTEGLVTSILLLGAAFGALLCGRLADRYGRRKMILNLSFLFFLASLGTALAPNVFIMAVFRFLLGLAVGGASAMVPAFLAEMAPHEKRGRMVTQNELMIVGGQFLAYVFNAILGVTMANTGHVWRYMLVICAVPAIMLFASMLKVPESPRWLISKGKNSEALRVLKQIREDKRAEAECREIQEAVEKDTALEKASLKDFSTPWLRRLLWIGIGVAIVNQITGVNSIMYYGTQILKESGFGTKAALIANIGNGLISVIAVIFGIWLVGKVRRRPILLIGLAGTTTALLLIAIFSIVLDGSMALPYVVLSLTVLFLAFMQGCVGPVTWLVIAEIFPQRLRGLGSGISVFFLWILNFVIGFAFPILLSSVGLSFTFFIFVALGVLAIGFVYKFMPETKGRTLEELEEHFRSRHDHNTPEQSVIEV
What are the official names of this protein?
Putative metabolite transport protein YncC.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DDX60_HUMAN
Sequence: MERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRSQAPVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSISVSLRELCENEDDNVVLAFEQLSTTFWEKLNKV
What is the function of this protein?
Positively regulates RIGI- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection.  Binds ssRNA, dsRNA and dsDNA and can promote the binding of RIGI to dsRNA.  Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV).
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX60, DEAD box protein 60.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTX2_MOUSE
Sequence: MAMAPSSSLPQVYPSHVVVAVWEWQDGLGIWHPYSATVCSFIEQHFVRQRGQHFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQNTGTMRSVRRHLFSQNSAPGQGIVWEWLGDDGSWVAYEARICDYLEQQVARGIQVVDLAPLGYNYTVNYATLTQTNKTSSFCRSVRRQVGPVYPVTSDIAVPRQMGLICFCQQCLHGSGTGPVSGRYRHSMTNLPAYPAPQAPHRTTTVSGAHQAFAPYNKPSLSGARSAPRLNTTNPWAAAPPVAGNQSLFHSSLSHLGPQLLPSGPSTSSGASASFPSGPSSSSPGSAPTTVPVQMPKASRVQQALAGMTSVLSAIGLPVCLSRAPRPTGPPASRPASKSHSSVKRLRKMSVKEGAPKPEPEQVIRKYTEELKVAPEEDCIICMEKLAVASGYSDMTDSKALGPMVVGRLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPWGKMEVFRFQMSLPGHEDCGTILIVYNIPHGIQGPEHPSPGKPFTARGFPRQCYLPDSPQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ
What is the function of this protein?
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.  Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context.  Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1.  Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity).
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase DTX2, Protein deltex-2, Deltex2, mDTX2, RING-type E3 ubiquitin transferase DTX2.
What is the protein family that this protein belongs to?
Belongs to the Deltex family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Partially nuclear.
Protein: DAPB_HAES1
Sequence: MTLKIGIVGAGGRMGRQLIQAVYHTEGVELGAAFERVGSSLVGTDAGELAGVGKLGIKVSDNLTQEKDNFDLLVDFTRPEGTLQHLAFCVEHHKNIVIGTTGFDDQSKQAIQQAAQNIAIVFASNYSVGVNLVFKLLKKAAKVMGDYCDIEIIEAHHRHKVDAPSGTALSMGEHIAKTLGRDLKTHGVFSREGITGERKPDEIGFSTIRAADVVGEHTVWFADIGERVEISHKASSRMTFANGAVRAAKWLSTKQEGLFDMTDVLDLNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARL8C_ARATH
Sequence: MGLWDSLLNWLRSLFFKQEMELSLVGLQNAGKTSLVNAIATGGYSEDMIPTVGFNMRKVTKGNVTIKIWDLGGQRRFRTMWERYCRGVSAIVYVIDAADRDSVPISRSELNDLLTKPSLNGIPLLILGNKIDKSEALSKQALVDQLGLESVTDREVCCYMISCKDSINIDAVIDWLIKHSRTAT
What is the function of this protein?
(Microbial infection) Component of tomato mosaic virus (ToMV) RNA replication complexes.  Required for tobamovirus multiplication, especially for efficient negative-strand RNA synthesis and viral RNA capping.
What are the official names of this protein?
ADP-ribosylation factor-like protein 8c, AtARL8c, ADP-ribosylation factor-like A1A, AtARLA1A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Late endosome membrane. Lysosome membrane. Cytoplasm, cytoskeleton, spindle. Note=Localizes with microtubules at the spindle mid-zone during mitosis.
Protein: ATPF2_RHOBA
Sequence: MKRLLAISSLTLLASLVLLVVSPARSLAAQDEVTVVDALADAADSEDGDHDHDHEGDDHGHDEAAGDEHGHGDGDHAATPLLSFDGGSAIWNLIIFLCVLAILSKFVWPAVLGGLQAREEKIREDLESAEKASAEAKQMLSDYQLKLDEAASQVQTMLADARRDAEANGQKIVDAAKVEAAAQRERALSDIENAKKVAMAEMAGQTSKLAMQVARSVVGRELSADDHADLIRQSMERLPSQN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SCAM1_ORYSJ
Sequence: MAGRYDSNPFEEDDVNPFSEQARGKAGGQPSYGGGAFYMPNPRNVPSVSSNSRLSPLPPEPAAFGATVDIPLDSSKDLKNREKELQAREAELNKREKELKRREEAAARAGIVIEEKNWPPFLPLIHHDITNEIPSHLQRMQYVAFASFLGLACCLFWNVIAVTSAWVKGEGVKIWLLAIIYFISGVPGAYVLWYRPLYNAMRTDSALKFGLFFLVYLFHILFCVFSAVAPPVVFEGKSLAGILPAIDLISKNALVGIFYFVGFGLFCVESLLSIWVIQQVYMYFRGSGKAAEMKRDATRGAMRAAF
What is the function of this protein?
Probably involved in membrane trafficking.
What are the official names of this protein?
Secretory carrier-associated membrane protein 1, Secretory carrier membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the SCAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein.
Protein: RS13_SPOFR
Sequence: MGRMHAPGKGISQSALPYRRSVPTWLKLTADDVKEQIFKLGKKGLTPSQIGVMLRDSHGVAQVRFVTGKKILRIMKAMGLAPDLPEDLYYLIKKAVAMRKHLERNRKDKDSKFRLILVESRIHRLARYYKTKSVLPPNWKYESSTASALVA
What are the official names of this protein?
40S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PISD_MOUSE
Sequence: MAASGGRACVRSLRGGVLWRSSPCHYESTATRHFLGTLQKLPLQAGVRNFHTAPVRSLFLLRPVPILLATGGGYAGYRQYEKYRERKLEKLGLEIPPKLASHWEVSLYKSVPTRLLSRACGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHCVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGPRANTEDLPFPPASSSDSFRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPRYSKGSYNDLSFVTHANKEGIPMRKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKIRFGEALGSL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.  May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane (By similarity).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
Protein: NRDR_OCEIH
Sequence: MRCSNCQNKNTKVLDSRPIEEGRAIRRRRECERCGFRFTTFERIEEVPLIVVKKDGVRQEFSREKLMRGLIRACEKRPVALETIESIALEVEKKLRNAGNPEVSSNSIGEMVMELLSKVDEVSYVRFASVYRQFKDITVFLDELKDIINTDKSMKDK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: EF2_HALSA
Sequence: MGRRKKIVEQCERLMDNPEQIRNIAIAAHVDHGKTTLTDNLLAGAGMISEDTAGQQLAMDTEEDEQERGITIDAANVSMTHEYEGDDHLINLIDTPGHVDFGGDVTRAMRAVDGALVVVDAVEGAMPQTETVVRQALREGVKPTLFINKVDRLISELQEGPEEMQERLLSVIGDVNELIRGMTEEKDDIEDWTVSVEDGTVAFGSALYKWGVSMPSMQRTGMDFGDIIDLERSDKREELHEQTPLADVVLDMVAEHFPNPIDAQPRRIPTVWRGDADSEIAESMRLVDEDGEVVLMVTDIGVDPHAGEIAAGRVFSGTLEKGQELYVSGTAGKNRVQSVGIYMGGEREEVDEVPAGNIAAVTGLKDAIAGSTVSNEEMTPFESIDHISEPVITKSIEAQNMDDLPKLIETLRQVSKEDPTISIEINEDTGEHLISGQGELHLEVQTQRIERNQGIPVTTGEPIVVYRETPTSDSQEVEGVSPNRHNKFYITVEQLSDDVLEEIRLGEVSMDMPEQERREVLQEAGMDKETSQDVENIIGRNIFIDDTKGIQHLNETMELVVDGLTDSLEDGPLAAEPVEGALIRLHDARLHEDAIHRGPAQVIPATRDAVHRALIDADIRLLEPIQDVRIDVPSEHMGAASGEVQGRRGRVDDMYQEGDLMVVEGIAPVDEMIGFSSDIRSATEGRASWNTENAGFRVMADNLQREIIMEIRERKGMKTELPESITHF
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG3_DANRE
Sequence: MQNVINSVKGTALGVAEFLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWKWASGEEAKVKPYLPNDKQFLLTRNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTFHNSGVTGVTEAVREISLDNKDNMNMNVKTGACGNSGDDDDDEEGEAADMEEYEESGLLETDDATLDTSKMADLSKTKAEAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEDRQPLTVDQMYEDISQDHVKKTVTIENHPNLPPPAMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8-like proteins (gabarap, gabarapl1, gabarapl2 or map1lc3a).  The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8-like proteins from atg3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of atg8-like proteins.  The formation of the atg8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of atg12 to itself, atg12 conjugation to atg3 playing a role in mitochondrial homeostasis but not in autophagy.  atg7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with atg3 (By similarity).
What are the official names of this protein?
Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_ACIBS
Sequence: MKFTTYTTFPEQTSNESLWILVDSEQLQSNLNTYQINNLESILTATQFKANFNETLPLFGQLSTQPHSQLLGLGKAAELQAAKLAKLAQTIIKSAQNKFKHIAIDIAALPVEYHYLFALSLTQAAYGYDEFKSTKNEFVLQQVDLISSQTSLDENQLALVHAVQSGQSYARDLGNRPGNICFPEYLAEQALALAAEFPDLLKVTVLNEQQMADLGMYAFLAVSKGSERPGRIVTLEYQAQLEQAPVVLVGKGVTFDTGGISLKPGLGMDEMKFDMCGAASVLGTIRALCEARLPIHVVGAIAAAENMPSGKATRPGDIVTTMSGQTVEILNTDAEGRLVLCDTLTYIKRFNPAVVIDIATLTGACVVALGKVLSGLFSPDDTLAAELQQAGEQSFDRVWRMPVIDDYQELLDSPFADIANIGGPHGGAITAACFLERFTRDYRWAHLDVAGTAWLSGSAKGATGRPVPLLMQFLANRVSTNG
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_PROMA
Sequence: MDLAFSTEENIAAIASAVAPGQGAIAIVKVSGASAKEVVKNVVRTPSNKIWSSHKILYGHVIDKSTKKNIDEVLILIMDGPRSFTGEDVVEIHCHGGLIVVQQVLDAILKQPKTRRAFPGEFSQRAVLNGRLDITQAEAINDLIHARSQKAAQLAIAGIDGDITNKINYLREKLLDQLSEIEARIDFEEDLPKLNSKKLLTDLMLIRAELKQLINDAKQGSLIRNGLKVALVGLPNVGKSSILNLLSKHERAIVTDLPGTTRDLLESEIILEGVPITLIDTAGIRETNNEIEKIGVSLSQKTLFTADIVVLIFDLSKGWNKNDQNLLEKIPKGTPTLIIGNKADLKSQSTNIQPHATMTAITGEGEKELIQELLKLAGANELEGIEVALNQRQLDLVKVAVNALDQIEKVAAESLAWDFWTIDLREAIYKLGELTGEEVTEALLDRIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF7_BYDVP
Sequence: MYTRSSGLKTLKLDDLVQVVKLTRVDTPHPAQHVGIPTIRNVGLLEPLPVMQGRV
What are the official names of this protein?
Uncharacterized protein ORF7.
Protein: TOLB_BURCH
Sequence: MSLMTKLGFRALVASCLITAGSAANAQVNVLITGVGSTQFPIATANFTNEANLPQQVTSIVRADLARSGKFTNIDAGSTPVPETASVDLGAWKAKGANAFVAGSVNRDANGQYKVNFILYDTVKQQSLGGLSLTATDTTLRTAGHKIADYIYQKLLGVRGVFATRLSYVIKTGNRYQLQISDSDGQNARIALSSTEPIISPAWSPSGTKVAYVSFERKKPIVYIHDLPTGRRYMVSDQKGNNSAPAWSPDSNTLAVALSLTGNTQIYTVNANGGGLRRLTQSSSIDTEPFYSPDGRWIYFTSDRGGAPQIYRMPAQGESAGAAQRVTFTGSYNTSPRVSPDGKLLAYISRTGGGFKLYVQDLQTGAANAITNTNRDESPSFAANGQYVLYATQSGGRNVLAAVPSDGSAPPQILSVQGGSVREPSWGPFMQ
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MTFA_ECO24
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPGFPSLWQRFCQFYQQDPLQRLHRTNDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_COXB2
Sequence: MIYRYLRPWLFKLEPETAHALTLNCLKWFYCYWLINRRLQRFPQKPTVVFGIEFPNPVGLAAGLDKNGEYMDELLGLGFGFIEVGAVTPKPQPGNSKPRIFRLPQARALINRMGFNNLGVDYLVEQLKRRKVKGIVGVNIGKNLTTPLEKAHEDYQNCFEKLYSYVDYVTINISSPNTPELRQLQSERYLADLLTRLKEDQRRLEDQYHKRVPLFLKIAPDLTPEEIQTIATLALQHRIEGIVATNTSCSRQGTEKLPNANEAGGLSGKPLFPMTLQVVKQLHSFLGDEIPIVAVGGIFSGENAQTLINAGARLVQLYTGLIYEGPELVKNIVEFLTLSRQTREGIN
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ASK1_YEAST
Sequence: MDSASKEETLEKLDQEITVNLQKIDSNLSFCFHKITQDIIPHVATYSEICERIMDSTEWLGTMFQETGLVNLQANAAAPVGNAPVKSLVSNNVGIFPTSAEEASRQSQTDNGPNEADSAVHVNRDVHSMFNNDSIDDFHTANITSTGQILKLPDSSDEDTGSEAVPSREQTDLTGEGHGGADDEQDESTIQRQSRKRKISLLLQQQYGSSSSMVPSPIVPNKMRKQLAHEEHINNDGDNDDENSNNIESSPLKQGHHHPKGQADDNNEGPDEEESTKEVPKPGTIIHFSTNR
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.  The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B.  Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
What are the official names of this protein?
DASH complex subunit ASK1, Associated with spindles and kinetochores protein 1, Outer kinetochore protein ASK1.
What is the protein family that this protein belongs to?
Belongs to the DASH complex ASK1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: IRAP_SHIF8
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPCQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_LEPCP
Sequence: MQIVHTLADLRAALAPVRRSAGTIAFVPTMGNLHEGHLALVRQARERVGAAGTVVASIFVNRLQFAPHEDFDRYPRTLARDAELLAPAGCDLVFAPAEAELYPQPQTFKVQPDPALAELLEGHFRPGFFTGVCTVVMKLFSIVQPQVAVFGKKDYQQLMVLRRMVEQFALPIEVLGGETLRAHDGLALSSRNGYLGAAEREQALQLSAALRDLLGAVRAGGAPLETLEAQACTALRAQGWLPDYLCVRRRTDLLPPGADEIAAGLPLVALGAARLGNTRLIDNLEG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_LACAC
Sequence: MKVIVTENKIQGSAKAFEIFEKGIKNGAKVLGLATGSTPEILYQNWVKSDLNCDDLTSINLDEYVGLTPDNPQSYHYFMQKHLFDKKTFKKTYIPDGMTKDVPAYCKEYDQIIKDNPIDIQLLGIGQNGHIAFNEPGTPFDIGTHEVKLTENTIKANARFFDNEDEVPKSAICMGTANIMDSKKIVLMAFGEKKAKAIKEMIEGPITEEVPASILQKHPDVTVIVDTYAAQELDDKYKN
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.