PharMolix/UniProtQA huggingface dataset:
Protein: ASPD_BURTA
Sequence: MRNAHAPVDVAMIGFGAIGAAVYRAVEHDAALRVAHVIVPEHQCDAVRGALGERVDVVSSVDALAYRPQFALECAGHGALVDHVVPLLRAGTDCAVASIGALSDLALLDALSEAADEGGATLTLLSGAIGGVDALAAAKQGGLDEVQYIGRKPPLGWLGTPAEALCDLRAMTAEQTIFEGSARDAARLYPKNANVAATVALAGVGLDATKVRLIADPAVTRNVHRVVARGAFGEMSIEMSGKPLPDNPKTSALTAFSAIRALRNRASHCVI
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: NPM_HUMAN
Sequence: MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
What is the function of this protein?
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF.  Binds ribosome presumably to drive ribosome nuclear export.  Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids.  Acts as a chaperonin for the core histones H3, H2B and H4.  Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA.  May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules.  In concert with BRCA2, regulates centrosome duplication.  Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication.  Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.  Antagonizes the inhibitory effect of ATF5 on cell proliferation and relieves ATF5-induced G2/M blockade (PubMed:22528486).  In complex with MYC enhances the transcription of MYC target genes (PubMed:25956029).  May act as chaperonin or cotransporter in the nucleolar localization of transcription termination factor TTF1 (By similarity).
What are the official names of this protein?
Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin.
What is the protein family that this protein belongs to?
Belongs to the nucleoplasmin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Generally nucleolar, but is translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. Has been found in the cytoplasm in patients with primary acute myelogenous leukemia (AML), but not with secondary AML. Can shuttle between cytoplasm and nucleus. Co- localizes with the methylated form of RPS10 in the granular component (GC) region of the nucleolus. Colocalized with nucleolin and APEX1 in nucleoli. Isoform 1 of NEK2 is required for its localization to the centrosome during mitosis.
Protein: LPXB_ALKEH
Sequence: MRVALVAGEHSGDRLGAGLIRAIRARCPEAEFDGVGGPLMQAEGLRSHYPMEALSVMGLVEVLRHLPRLLRIRRDLVARYRTDPPDVFVGIDLPDFNLSIERRLKAVGVPTVHYVSPQVWAWRQGRVRTIGRSVDRILALYPFEAEFYRRHGVPVDFVGHPAADRFPLQPDAGAARAALGLVDDGGGPWVALLPGSRLGEVQRHAELYARTVARLRERQPDVRFIAPLAWPGLRAVFYEALVQQGVSDAVQLFEGRADEVMAAADVVLTASGTATLEAMLLKRPMVVAYRLAPLTFWLMKRLVRVSHVSQPNLLAGEGLVEEYLQDAATPDNLAYALYRLLNDEPRSAYLRARFAELHGTLRRGADGQAAAAVLAAAGGNGS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: ICEA_PANAN
Sequence: MKEDKVLILRTCANNMADHGGIIWPLSGIVECKYWKPVKGFENGLTGLIWGKGSDSPLSLHADARRVVAEVAADECIAIETHGWIKFPRAEVLHVGTQNSAMQFILHHRADYVACTEMQAGPGGPDVTSEAKAGNRSLPVTDDIDATIESGSTQPTQTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGSDSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEDNSLTAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTSGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAEEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTAQEQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTAGYHSILTAGYGSTQTARTRSDLTTGYGSTSTAGPDSSLIAGYGSTQTAGYNSILTAGYGSTQTGQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDCILMAGDRSKLTAGINSILTAGCRSKLIGSNGSTLTAGENSVLIFRCWDGKRYTNVVAKTGKGGIEADMPYQMDEDNNIVNKPEE
What is the function of this protein?
Ice nucleation proteins enable bacteria to nucleate crystallization in supercooled water.
What are the official names of this protein?
Ice nucleation protein InaA.
What is the protein family that this protein belongs to?
Belongs to the bacterial ice nucleation protein family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: FLIE_HALH5
Sequence: MAEIQTVTAPVFLNQANSSSVNKHTPAEAQETFKQALSQAINNVNDLQKVSAEKTELLAKGKIEDLHDVMITGQKASITLSATVEIRNKVIEAYQEIMRMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
Protein: NFI_AZOVD
Sequence: MPDSPFGDWDGTPAGARLLQQELAGRVVLRDDFPDLGLIAGVDVGFEEGGGITRAAAVLLDANTLGVLAESLVRIPTSMPYIPGLLSFRELPAVLRALAELPRVPDLVFCDGQGIAHPRRLGIAAHLGVVSGLPTIGVAKKILVGTHAELGSHRGDQVPLMYRGEVLGAVLRSKDRVRPLIVSPGHRVSLASAPRLVMACVTRYRLPEPTRLADRLASRRA
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYP8_CAEEL
Sequence: MPPEVRGNKRAFFDISINGEPAGRIVFSLWNHCCPRTVENFRAFCTGELGKMNGHYASYQGSVFHRVIKGFMIQGGDITHGNGTGGYSIYGRTFDDENLALKHKKPYLLSMANRGPDTNGSQFFITSEEVPHLDGKHCVFGEVIKGVEVVKAIENLETGNEDKPVCKVEITHCGEMVRKGDVVGNAGAAASEPEPTGVKMEDEPKTRNWLMRYSKSPESREEKKKDKHGREEKRDRRRRSNDRHGRDRRSRSRSQSRDRNRRRDDRSGRDGRVGRNERDDRSGRDERRDDRRSAPTKDGIKVRGRGKLTFLGGRTRSTTPPHWKREESKKLTLEAHQKRQEELEERQKRAAQREKEEAERNARLEKERVERQNQRELERQKQEAERELKRQQENEESGNRRRRRSSRSGSENDESELEEPKNRSASPRKRSSSSSSSSSSGHSSDSD
What is the function of this protein?
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:8694762).  May play a role in the protein folding, transport and assembly (PubMed:8694762).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase 8, PPIase 8, Cyclophilin-8, CYP-8, Rotamase 8.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: ERA_BORAP
Sequence: MKSGFAAILGRPSTGKSTLLNSICGHKISIISPIPQTTRNKIKGIFTDDRGQIIFIDTPGFHLSKKKFNIAMMNNIHSSIGEVELILYIIDIQDTPGEEENKMLEIIKNSKIKFLVLLNKVDLKNTKIKEITQFLKEKGIEDSNIIKISAEKKINTEELKNKIYENFSEGPLYYPQEYYTDQKINFRISEIIREKAIENLKEELPYSLYVDIDTLENKKRGLFIRANIFVANESQKGIIVGKNGKEIKSIGERARKTIAKIFETKCNLFLQVKLKKNWNKEDKLIKRLIN
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RL13_LACCB
Sequence: MRTTFLAKPGEIERKWYVVDATDIPLGRLSSVVASILRGKNKPQFTPNVDTGDNVIIINASKLKLTGKKASDKIYYHHSQHPGGLKHEIAGDLLRDNPARLVEYSVKKMLPTKNTLGHQQFLKLHVYAGEEHPHLAQKPEVLDISNLI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: YF75_SCHPO
Sequence: MQSIIIRQYRFLARYLEPEFVKDPALRNANARPREKLQRLSHIQFSELLTDVADELQRRINNDPKVRFLPPVDSYHPKRNHARQKLSSLAPTRLRDLCMDVFFEVQSRYSGALKEVSSNTPPNMTRAASQPPPQVQRLPASAPKHDLYSSANASSASLHPTEQRTTSSPTIPSYANRTHTDSPTSLSHRLPNVPDTNALNTVQANNSSTSSLSQGAQTGIDSSSNYLSRIEMLESSLAKSNSLLDSSKSEMEALKAKSISDATKHKNEIFQLEEKLHEASHEAEISIKKLNDAENRIKELENNPTLSFNPELEKNLKLMQELIVAESSKTQHIVELESCIDSLKAETERWKKVAINAKSAKIDEDIRLFTMTTVPMKSIRELISPNGFLDEQLYIRYFVEMNVFVASLRRDSPSQWMSTAKDIALTLEAIVSSLREKSLLEELPDLGKKVDDLCSFTNSLMEQVRLAVINGALLPIYHVDASACSISISLMDIAKTYGLTNTGKSSLSVGRNSLHPVDDLKALSVAKTLLSEKSKQFSETNQKLLDAISSDSSSSTIQQRVHEDINVIRDTLFDVSSPLELMRDRAAYAVIHNALQEMRRYCMQLIEQEGHGENFGFTDNNSVPPLTDLAFSAAKCFKDILRAIEDAEFSVQRTQFSTR
What are the official names of this protein?
Uncharacterized protein C3G9.05.
What are the subcellular locations of this protein?
Barrier septum. Cell tip. Note=Localizes at the barrier septum and the cell tip.
Protein: HPR_BACAA
Sequence: MKSGEKDYSVKEAMIFSQRIAQLSKALWKCVEKDWQMWIKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDDKRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIELIAILRNIYGQDFIDIFEKSLEDIEENFTESDQKLVKK
What is the function of this protein?
Negative regulator of protease production and sporulation.
What are the official names of this protein?
HTH-type transcriptional regulator Hpr, Protease production regulatory protein Hpr.
Protein: RL31_LEPIN
Sequence: MKTEIHPNYKAAKISCASCGTVYETRTSIGDINIEICSACHPFFTGKSKLVDTTGRVDKFKKKYKMQ
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: NQOR_BRUAB
Sequence: MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEVPIATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGGAELALISTQWQMQHHGMIIVPLSYAYREQMGNDVVRGGAPYGMTTTADGDGSRQPSAQELDGARFQGRRVAEITAKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: FOLD_CAUSK
Sequence: MSQARIIDGKAFAARLREQVAAEVAVLKAEHGLTPGLAVVLVGEDPASQVYVRNKGEQTLAAGMHSETHRLPANASQAELLSLVDRLNDDPAIHGVLVQFPVPDHLSQAAIVAAISPDKDVDGLTVVNAGRLASGLPALTSCTPAGCMVLLRDVVGDLTGKRAVVIGRSNLMGKPMAQLLLAADCTVTIAHSRSRDLPAICREADILVAAVGRAEMVRGDWIKPGATVIDVGISRFPSRDPVAAAAGKTRLVGDVAFDEAKEVAGAITPVPGGVGPMTIAMLLANTVSAAKRLNGIAE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RS12_RALSO
Sequence: MPTINQLVRKPRVSEKLKSKSPALENCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQARSKYGAKRPKAA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DCNL4_MOUSE
Sequence: MHSDAAAVNFQLNSHLSTLASIHKIYHTLNKLNLTEDVGQDDHQTGSLRSCSSSDCFSKVMPPRKKRRPASGDDLSAKKSRHDSMYRKYESTRIKTEEEAFSSKRCLEWFYEYAGTEDAVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQCDTTEKLRTTLDYLRSLLNDTTNFKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWPLFPVFHQFLEQSKYKVINKDQWCNVLEFSRTISLDLSNYDEDGAWPVLLDEFVEWYKDKQMS
What is the function of this protein?
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which are necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs).
What are the official names of this protein?
DCN1-like protein 4, DCNL4, DCUN1 domain-containing protein 4, Defective in cullin neddylation protein 1-like protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: RHAB_LISMC
Sequence: MKHYVAVDIGASSGRLILGKLVNEKLQLEEIHRFKNGFTYRDGHERWEIDQLMQEIFIGLEKVKQLGISECVLGIDTWGVDYVLIGASGEKLADPISYRDKRTLNAVQNLTSEYPREYIYKKTGIQFMELNTLYQLYVEERDLLERAEKILLIPDYIGYVLTGVKVAETTNSSTTQMLNLREQLFDKDLLSHLNIDVEKFAPLTDAGTYLGKVKEEWLEEYDIPNCDVVTVATHDTASAVVGTPAEGENWAFLSSGTWSLIGMELSAPINNEAAFKENYTNEWGAYGTYRFLKNIMGLWIVQEIARMDDYKHSFAEMAEEASNYPYFKQIINVNDARFNNPENMVDEIKLYCQETGQTIPETIGELTNCVYGSLALYYALELEKMTEITGKKIEKLYIVGGGSNVAMLNQLTAKLAGIEVFAGPSEATAIGNLVVQMINQGEIESMRAGRKIIRNSFEIGEFSCGDVRFEEIKERFTKVLEFN
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: ERPA_ECOK1
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: NUSB_DESAL
Sequence: MGKRRRARELALQSLFYVDSTSAPPLEALDLFCQNFPPPKDLAQFFYELAKGVINNQDEIDRLIEQHSNNWKLYRMSAVDLNLMRIAAYEFLFCPDVPRRVSINEAIDIGKRFGTAESGAFINGILDSIHLHLGKEEKAEKKR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SYFA_BACAN
Sequence: MEARLKELKQKALELIEEAKELKGLNDVRVAYLGKKGPITEVLRGMGKLSAEERPRMGALVNEVREAIQTRLDDKISNLEKAVIEAKLATETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFGEDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_BURTA
Sequence: MKALAKLERGPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNREGAFAEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNLVGEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKMVAMLQSGLDLSPIITHRFAVDDYEKGFAAMLSGESGKVILDWAAA
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAD57_YEAST
Sequence: MPRALSIKFDNTYMDLYDELPESKLLYDEEFSYLLDAVRQNGVCVVDFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNGPECFTTADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCVYITTEGDLPTQRLESMLSSRPAYEKLGITQSNIFTVSCNDLINQEHIINVQLPILLERSKGSIKLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILAHDYSLSVVVANQVGDKPLANSPVAHRTYVTDYDYQLGWLVGWKNSTILYRQMNSLLGASSNNDEILSDDEDYMLIERVMSTVNDRNYDFFSKKKPPIIENKTVERNSSSPISRQSKKRKFDYRVPNLGLTWSNHVSTRILLQKSFKASTIIQRGEAHLYKGGDSASFWQVKRTMKVVYSTFAKPGQIAYQITKRGIETA
What is the function of this protein?
Participates in the repair of X-ray-induced damage to DNA and in meiosis.  It may act in part by stabilizing a repair complex of other RAD genes.
What are the official names of this protein?
DNA repair protein RAD57.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KEFB_ECOBW
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKVGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BHMT1_MOUSE
Sequence: MAPVAGKKAKKGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAGGVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASGRPYNPSMSRPDAWGVTKGAAELMQQKEATTEQQLRELFEKQKFKSAQ
What is the function of this protein?
Involved in the regulation of homocysteine metabolism.  Converts betaine and homocysteine to dimethylglycine and methionine, respectively.  This reaction is also required for the irreversible oxidation of choline.
What are the official names of this protein?
Betaine--homocysteine S-methyltransferase 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Predominantly localized in the cytoplasm with a small fraction detected in the nucleus. Translocates into the nucleus upon oxidative stress.
Protein: COAD_PSEFS
Sequence: MNRVLYPGTFDPITKGHGDLVERASRLFDHVIIAVAASPKKNPLFPLEQRVELAREVTKHLPNVEVVGFSTLLAHFAKEQNANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSERYSFISSTLVREIAALGGDITKFVHPAVADALTLRFKK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U6DD_CONCL
Sequence: MKFPLLFISLALAAFLTRVQDADSSVISKEKSVRDGEEFPCAGTMADCRGLADNSVCCDTGKCIGEVCYY
What are the official names of this protein?
Conotoxin Cl6.13.
What are the subcellular locations of this protein?
Secreted.
Protein: OPGD_SALTI
Sequence: MNRRRFIKGSMAMAAVCGSSGIASLFSQAAFAAESDIADGKIVRFDFAGLQSMAQALAKKPWGGAPGPLPDTLANLTPQAYNSIQYDAAHSLWNGVANRQLDIQFFHVGMGFRRRVRMFSVDTTTHLAREIHFRPELFKYNDAGVDTTQLEGQSDLGFAGFRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDGQEEFPDFTAFWFDTAKPGDTTFTVYALLDSASVTGAYKFVIHCEKTQVIMDVENHLYARKDIKQLGIAPMTSMFSCGNNERRVCDTIHPQIHDSDRLAMWRGNGEWICRPLNNPQKLQFNAYMDDNPKGFGLLQLDRDFSHYQDVMGWYNKRPSLWVEPRSKWGKGAVSLMEIPTTGETLDNVVCFWQPEKAIKAGDTLAFNYRLYWSAQPPVQSPLARVMATRTGMGGFPEGWAPGEHYPDKWARRFAIDFVGGDLKAAAPKGIEPVITLSSGEAKQVEILYVEPFDGYRIQFDWYPTSDSTAPVDMRMFLRCQGEAISETWLYQYFPPAPDKRRYVDDRIMR
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HPF_BACSU
Sequence: MNYNIRGENIEVTPALKDHVERKIGKLERYFDHSVDADVNVNLKFYNDKESKVEVTIPMTDLALRSEVHNEDMYNAIDLATNKLERQIRKHKTKVNRKFREQGSPKYLLANGLGSDTDIAVQDDIEEEESLDIVRQKRFNLKPMDSEEAILQMNMLGHNFFVFTNAETNLTNVVYRRNDGKYGLIEPTE
What is the function of this protein?
Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.  May not be the only factor implicated (PubMed:22950019).  Might negatively regulate the activity of the sigma-54 factor (SigL) (PubMed:9852014).
What are the official names of this protein?
Ribosome hibernation promotion factor, HPF, Hst23, Putative sigma-54 modulation protein, SigL modulation protein.
What is the protein family that this protein belongs to?
Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT5B_PLEJO
Sequence: SGSCSLKTCWLQLADFRKVGDHLKEKYDSAAAMRINRKGKLELVNSRFNTPTVEDLVYTDQSPDYCLRNESTGSMGTLGRLCNKTSEGMDGCELMCCGRGYDQFKTVQVERCHCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-5b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.