PharMolix/UniProtQA huggingface dataset:
Protein: CTF18_EMENI
Sequence: MPFISSAELSSRATPPDLQKRKYGEQSQPSEPKRQKIMGGFLDDDDDDDHDGLEAFNEAQYQSEFEIQEQRVDLPQISQSGSRAEPKRPKIMGGFLDNDDDDDDGLEAFNDAHLESQIDTQEQPVKLTEVSRSQSTLESVVINSVTERSTIVPAYAPPNISPTSVKIKTCNGKALNVPLKKPSARVSYERLIASRSTTAPGRAQKSYYGIDIHSLLNESAKEVKAAEAPKPAPVADVRPSIEAPIGDKRSKKLSTAMWTEKYRARKYTELIGDERTNRSILRWLRGWDPIVYPSLARAKQNKKYNNDEEERPHRKVLLLCGPPGLGKTTLAHVCARQAGYEVLEINASDERSRDVVKGRIRDALGTENVKGMNVELGEQKVRKVGRPVCVVVDEVDGVVSGSGGSGEGGFMKALTDLVLLDQRNSARTSERASDGRKRKGDNFRFLRPLILVCNDVYHASLRPLRQSSVAEIIHVRQAPLENVVSRMKSIFTLEGIPSDSDGVRRLCEASWGLAKRKQRGVRSTGAAEGDIRSVLVAAEWVAHKLRNESSAPLRLTRNWLEQRVLADAGGGSFFKGMNRGGVRDIVDRVFTEGAGFPDVPLGDESLQDPYDRSEAVSVDVANIKKRHAIRRLCEMVDASGDHDRCTSECFSSYPLQPYQDDTFLTKPNAAYDWLHFHDTISSRIYSAHDWELGAYLSQATSAFHLLFATAQGKAQQQYREIDEEEEEAHPFSGPRADYAAFEATKQNQAILSTFQSSFSAPLLRLFRSSNNVATELIPNVIRMLSPDIKPVVVRGSEQKSVASVRKESERALVQSAVRVMTGLGVTFEKVRIENEGGGHGGWAYRMEPPLDALVSFSKVPGFSSATNPVRYAVRQVLDQEYRKESIRKNSENLSSTGSKKSTTKSDDIETPANPAEAAKLKYGTAVKRDFFGRIIQDRVPSPQEDMEQALSRKAKSAQQELSSAGRKVWVTYHDGFSNAVRKPISMAELLSGL
What is the function of this protein?
Essential for the fidelity of chromosome transmission.  Required for the DNA replication block checkpoint.  Replication factor C (RFC) complex has an essential but redundant activity in sister chromatid cohesion establishment (By similarity).
What are the official names of this protein?
Chromosome transmission fidelity protein 18.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. CTF18 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: COBT_OLEA2
Sequence: MSHSVEYIIQHIPPVDTSLAGAAQAHLDNLTKPRGSLGRLEELALRLYCIQGGDTPLAADPARIYTIAGDHGVAAEGVSPFPQEVTRQMVLNFLSNGAGINVLCNTVGCEQFVVDAGSCGGAYPEHPRLIQRKIHPGTASIAQGPAMTAEQCRQALQLGIDLAGMAREAGCRTVGTGEMGISNTTPSTALYCAYLGLDPAGITGPGAGITPDLVKHKTDIIRRALAVNAGAVQSQNAVDILAALGGYEIAALTGLILGAAYHRMAVLVDGFISTAAWTAAWKICPAVSDYSFFSHASAEAGHKTALRSMGIEPLHDLGLRLGEGTGAALTLFLLRSAAAIFNDMATFSSAGVATQSSC
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: GCSP_PECAS
Sequence: MTQTLSQLEHDGAFIERHIGPSVSQQQHMLSVVGATSLDALIRQIVPADIQLPSPPAVGEAVTEHEALAELKAIAGRNQRYKSYIGMGYSAVLMPPVILRNVLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTQDLTGLDLASASLLDEATAAAEAMAMAKRISKLKQAERFFVADDVHPQTLDVVRTRAETFGFEIVVGKAEEALKDDAVFGVLLQQAGTTGELHDYSDLMAALKARKVVSCVASDIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFACRDEHKRAMPGRIIGVSRDAAGNTAFRMAMQTREQHIRREKANSNICTSQVLLANIAGMYAVFHGPEGLKRIAGRIHRLTDILAAGLTQGGLLLRHRSWFDTLTIEVADKDVVLSRALSFGINLRSDLASAVGITLDEATTREDVLALFAVLLGDDHGLDIEALDASIAQEVATIPAGLLRHDAILSHPVFNRYHSETEMMRYLHRLARKDLALNQAMIPLGSCTMKLNAAAEMLPITWPEFAELHPFCPPEQALGYRQMIEQLSGWLVQLTGYDAVCMQPNSGAQGEYAGLLAIRRYHESRNEAGRHLCLIPSSAHGTNPASAQMAGMEVVVVACDKQGNIDLHDLREKAQAAGEQLSCIMVTYPSTHGVYEETIREVCQIVHQYGGQVYLDGANMNAQVGITTPGYIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHQVVKIDGVLTEQGAVSAAPFGSASILPISWMYIRMMGAEGLKQASQMAILNANYIATRLQQAYPVLYTGRDGRVAHECILDIRPLKESTGISEMDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESQVEIDRFIDAMLAIRSEINRVAQGEWPLDDNPLVNAPHTQAELVADWAHPYSRELAVFPAGSEHKYWPSVKRLDDVYGDRNLFCSCVPMSDYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: Y677_HAEIN
Sequence: MKLFKAEQWNIEVLLPLFEAYRQAYGQAENPERTLAFLTNRMRFNESLFFIAVDENEKAIGFVQLFPRLSSLQLQRYWQITDIFVLEHAQQTEIYAALISKAKDFVHFTQSNRLVAELAQNQYSMLESEGFKLNPKERLFELSLSC
What are the official names of this protein?
Uncharacterized protein HI_0677.
Protein: NDB4T_CHATC
Sequence: MNSKYLFVFLILNVIFIDLCQGFLWSLIPSAISAVTSLIKKGRRRRELGSQYDYLQDFRKRELDLDDLLSKFPDY
What are the official names of this protein?
Peptide Ctri10036.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_AZOC5
Sequence: MIETKPIDGKAFAAGLRARIAEEVAVLVRDHDLKPGLAVVLVGEDPASQVYVRNKAAQTAEAGMASFEYKLPADTAEADLLALVEKLNADPAVNGILVQLPLPAHLDSMKVLAAIDPAKDVDGFHVVNAGRLAVGLDALVPCTPLGCVMLLKHHLGNLSGLNAVVVGRSNIVGKPAAQLLLREDCTVTIAHSRTRDLPGMCRQADILVAAVGRPEMVRGDWIKPGATVIDVGINRVPKADGKTRLVGDVAYEEALGVAGLITPVPGGVGPMTIACLLQNTLTAARRQKGL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: APOA5_MOUSE
Sequence: MAAVITWALALLAVFASTQARKSLWDYFSQNSWSKGVMGQPQKLAQENLKGSFEQDLYNMNNYLEKLGPLRGPGKEPPLLAQDPEGIRKQLQQELGEVSSRLEPYMAAKHQQVGWNLEGLRQQLKPYTAELMEQVGLSVQELQEQLRVVGEDTKAQLLGGVDEALNLLQDMQSRVLHHTDRVKELFHPYAERLVTGIGHHVQELHRSVAPHAAASPARLSRCVQTLSHKLTRKAKDLHTSIQRNLDQLRDELSAFIRVSTDGAEDGDSLDPQALSEEVRQRLQAFRHDTYLQIAAFTQAIDQETEEIQHQLAPPPPSHSAFAPELGHSDSNKALSRLQSRLDDLWEDIAYGLQDQGHSHLSDPEGHSG
What is the function of this protein?
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL.  May also be associated with chylomicrons.  Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate).  Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages (By similarity).  Binds heparin (By similarity).
What are the official names of this protein?
Apolipoprotein A-V, Apo-AV, ApoA-V, Apolipoprotein A5, Regeneration-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Early endosome. Late endosome. Golgi apparatus, trans-Golgi network. Note=In the presence of SORL1, internalized to early endosomes, sorted in a retrograde fashion to late endosomes, from which a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network.
Protein: ILVC_LEIXX
Sequence: MAEIYYDNDADLSIIQGKKVAVIGYGSQGHAHAQNLRDSGVEVVIGLKDGSKSTPKAEEAGFRVLSAAEAAQWADVVVILAPDQVQRTLYADDIRANLEAGNALVFGHGFNIRFGYIEAPEGVDVIMVAPKGPGHTVRREYEAGRGVPVIVAVEKDATGAAWPLVLSYAKGIGGLRAGGIKTTFTEETETDLFGEQAVLCGGVSQLVQYGFETLTEAGYQPQVAYFEVLHELKLIVDLMWEGGIAKQRWSVSDTAEYGDYVSGPRVIGPHVKENMKAVLSDIQDGTFAKRFIADQDAGAPEFLALRVKGEQHPIEATGRELRKLFAWNASNDDDYVDGEVAR
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CPG4_CAEBR
Sequence: MLRVNLLILLCFVPFSLNNPLPTLPPDTANAYLRSFLPWWPNNTDFSLRAAPTPSESENSTEAVLLGAEYENGTDSTTGNQEDLDPATLRVQALPDSPLDALSPENAPKSFVSESMNHHDGNFIINFDEMGECPRDCSNDLREALGIVLQDMSHVERYHRICEKYSNASTCVNEDGRCDKDDRGMFEMMTSGLHYMCVEQELAFNATIKCIDDEAGLVQSECDAQCQTKNLFMNWMMRTAFQDTIQQGVNGIVGAATGTNANPLAFLQGAEGAAGGTPTGWADMLATVEQRPPSPQDAQQGFENFRQFTNDLCRIGDCMLDCIRSKFNTRCEGSAGTLLSEVFVRPIAASQNKLSILRPVLGSFMPEQCNYLTNNADLKKHRIDSTMDEELKRMYAEKMAKEIRDRNAQDELLSNLVPLDENGVPLPRALPELKSVDSPLDVSVKTLDQLILDMYSKNETKKAETTKKSYPNTTTVAPKNDDQAANTTAETTKTTSANITHVETTTLGNPKTEEVLSDVSLDTSGNNSTVADSGEGSAEGAGEGTEEDAEYSGSGNESTTEEEYSGSEEVSATDEGHPLAADESNEGLLTGSGEPAEEASGTGNSSVEGSGSGLDSLRSYIETSGEASGGAPGEASGEASGEASGEVSGEEEFSGYSGESPGENESSGEVPLTTTLHELY
What are the official names of this protein?
Chondroitin proteoglycan 4.
Protein: RLMH_SORC5
Sequence: MRLVVAAVGRVKDKPLRAAMDEYLGRIRRYVACDEIEIQDGPPAKVGPLLARASAGASVIAMEVGGKALGSEAFAAGVERWGSRGKGVVAFLIGGADGLPPDVSAAADDRWSLSPLTFPHRLARLVLIEQLYRAMTLLRGEPYAH
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_SALRD
Sequence: MSDDDSQDDSVPEGDPRRYATDFHAPVLSHDVQARLVTDASGRYVDATLGGGGHARALLDVLDPDGVVLGIDRDPEALETARDRLADEREAGRFWAVHGTFGNLRDVLAAEDLIPIDGLLLDLGVSSHQIDVPERGFSFRDEGPLDMRMDPQRGLTAQQVVNGWGERDLRDVLREYGEESRAGQIARALCDARPLDTTRALAEVVEDCAPPPDTVKTLTRVFQALRIVVNAELDELEQVLEQATEVVRTGGRIAAISYHSLEDRRVKRYLRYGNFEGEPRRDLYGTLVAPWAETPRGPIEAGESEVEANPRARSAHLRVAERRDDDEAGAPLPPLS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATD_PANVC
Sequence: MFDIGVNLTSTQFASDRQKVVKRARDAGVTGMLITGTNALESQHAQRLAEAQPGFCWSTAGVHPHHASEWSTEIASTLRRLAEKPEVVAIGECGLDFNRNLSAHEQQEYAFDAQLALAAELNMPVFLHCREAHARFAAVLEPWLPKLAGAVIHCFTGTRDELEACLAMGLSVGITGWVCDERRGLELRELLPLIPADRLLLETDAPYLLPRDMRPRPTSRRNEPCFLPHIVNQVATWRGESAEELATRIDQNARTLFRLA
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_SYMTH
Sequence: MKAILYVIVAVIALILGGAAGVAGGYYWFERESRKKLNSAEARARHIVDEALREAEAKKKEAILEAKEEVHRLRTEAERELKERRAELQRLERRVLQKEEQLDRKVEQLERKEETLSRKERELDRKNQQAQELVNKQMAELERISQLTMEEARELFLKQVEQEARADAAKLIREIDAEARENAEKRARELVGLAVQRVAADHSSELTVTVVSLPNDEMKGRIIGREGRNIRTLETLTGVDLIIDDTPEAVVLSAFDPVRREVAKIALQKLIQDGRIHPARIEEMVEKAQKEVEARIREEGDAACFELGIHNLHPELVKLLGRLKFRTSYGQNVLKHSIEVAHLAGIMAAELGVNVEVAKRAGLLHDIGKAVDHEIEGSHVAIGVSLLRRYKEHPDVIHAMECHHGDVEPRSVEAHLVAAADAISAARPGARRETLETYIKRLEKLEALADSFDGVDKSYAIQAGREIRVMVKPEKIDDYAALKLTKEIARKIEEELEYPGQIRVVVVRETRAVEYAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL6_RUEST
Sequence: MSRIGKKPVELPSGVSASLSGQTIEVKGPKGAQTFTATDDVTLTVEDNVVKVEPRGKSKRARQQWGMSRTMVANMVQGVTQGFKKELEIQGVGYRAQMQGNTLKLNLGYSHDVDFTAPEGVTITAPKQTEIVVEGADAQAVGEVAAKIRDWRRPEPYKGKGIRYKGEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HIS7_KLEP7
Sequence: MTQKYLFIDRDGTLISEPPEDFQVDRFDKLAFEPQVIPALLKLQQEGYKLVMITNQDGLGTDSLPQEAFDGPHNLMMQIFASQGVNFEEVLICPHFPGDNCACRKPKTQLVLPWLEEGVLDKSHSYVIGDRATDLELADNMGITGLRYDRETLDWPTICEQLTRSDRYAHVERITKETQVDVKVWLDREGGSKIHTGVGFFDHMLDQIATHGGFRMEVNVGGDLYIDDHHTVEDTGLALGEALKLALGDKRGINRFGFVLPMDECLARCALDISGRPHLEYKADFTYQRVGDLSTEMVEHFFRSLSYTMAVTLHLKTKGKNDHHRVESLFKAFGRTLRQAIRVQGDALPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF2_GIBBA
Sequence: QSATTCSSKPYSAQQVRAAANAACQYYQSNDTAGSTTYPHTYHNYEGFDFAVNGPYQEYPIRTSGVYSGGSPGADRVIINTQCQFAGAITHTGASGNQFVGCSNT
What are the official names of this protein?
Extracellular guanyl-specific ribonuclease Fl2, RNase Fl2.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease N1/T1 family.
Protein: DEGS_ECO57
Sequence: MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEYPATN
What is the function of this protein?
A site-1 protease (S1P) that cleaves the peptide bond between 'Val-148' and 'Ser-149' in RseA.  Part of a regulated intramembrane proteolysis (RIP) cascade.  When heat shock or other environmental stresses disrupt protein folding in the periplasm, DegS senses the accumulation of unassembled outer membrane porins (OMP) and then initiates RseA (anti sigma-E factor) degradation by cleaving its periplasmic domain, making it a substrate for subsequent cleavage by RseP.  This cascade ultimately leads to the sigma-E-driven expression of a variety of factors dealing with folding stress in the periplasm and OMP assembly.  Required for basal and stress-induced degradation of RseA (By similarity).
What are the official names of this protein?
Serine endoprotease DegS, Site-1 protease DegS, S1P protease DegS, Site-1-type intramembrane protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL32_BACHK
Sequence: MAVPFRRTSKTVKRKRRTHFKLSVPGMVECPSCGEAKLAHRVCKACGTYKGKEVISK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MRAZ_LIMRJ
Sequence: MLMGEFTHTIDSKGRLIIPAKFREQLGAHFIVTRGLDGCLFGYPLNEWAILEQKLKALPLTKRDARAFVRFLYSAATDCEIDKQGRINIPITLRTHASLEKKCVIVGVSNRLEIWSAERWNKFTSETADNFDEIAEDLNIDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: OBG_ORITB
Sequence: MQFIDEAKIFIKGGNGGDGCVSFRREKFVPNGGPDGGNGGCGGDIIFIGDRHLNTLINFKFKQHFLAQNGRAGAGNNRTGKSGQNLVLKVPVGTQILSNNKEHVIFDLTKDGQEFIIIRGGKGGLGNTYFKSSINQKPRKNTVGEIGDSMWVWLHLKLLSDVGLVGLPNAGKSTFLSAITSAKPKIADYPFTTLTPNLGVVYINNNSFVVADIPGLIAGAHLGQGLGDKFLKHIERCRIIVHLLDITAENLLQNYYTIRDELSSYSLSLKDKTEILCFTKTDTQSNEVIMSKLLELQPVINRVIYPISSYTKYGIKKLLANILSELQKS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG41_ICHVA
Sequence: MYLRDFHELAPSQTGKGYEVFFVVGFTKAGLKLGRLVLVNKRYLIQKKGCVTIPNKWMYWDPFQAFVVHDREYLQIFFRSLPEVIVNQLCLTHRFPQVSGSFTREICGFATDWIRNLVVSLDPRSEARLGLQQRLSLVDHLKTTFPDDYLDLRQLPPSTGGLYTTVSTAEMFNPTGTPDFLAAFDALFEEGGGTHKPPIQFPTVRFDKCEGTCEAADHIHELTRRIIGEVRRVYISNATGKVIPLLVVLTAVITAENRGVEVPERVGARPIHATGNIHFDTVLSYVVQMMYLGKVRVCAP
What are the official names of this protein?
Uncharacterized protein ORF41.
Protein: YR009_MIMIV
Sequence: MKSKQIIAFYVITTNYHHNKKTYKIGIHTGTLEDLISRYMTYFPDLIVKYFQYTVIAREVETNLKKNLRKHRVVNIKGGRSEWINMEYEKLYAHIKCEINSDKNIIINDVTNMELVNKYTKELLINKLSRTIYQTIFDIEICKPELLAGIDESKYNLDELLTKQTLSETKSLALKKMLFMKTFGITDSSHQEEFIEFYNEYASKIVIIRRFERFFSYDKQYNEIDYNLNHHNDGKDKLRDKIILEFINFILGKNKTNYKSDSLSYILSQDEHNTAVLTVAEQSMYFANEDKFRPLFNKNKGKFKEINEFNFKHYFETVQAILRSYGIDYCRGKRKRINGGREFEYSLSVNKQIRDIIDFKYGLSDSVNDFPNLFHK
What are the official names of this protein?
Uncharacterized protein R9.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R1 family.
Protein: SYM_CUTAK
Sequence: MSATDRVNLMCANVLAAVAWPYANGPRHIGHVSGFGVPSDVFARYMRMSGHRVLMVSGSDCHGTAISVKADQEGVTAQECAEKYHRIIAADLQGLGLSYDLYTSTLTDNHAHVTQEIFTRLHENGYVVKRSEMGAFEPSTGRTLPDRYIEGTCPVCGYDDARGDQCDNCGRQLDPADLIGPRSKTTGAAPEFRETEHFFLDLPALAESLASWIDTRTDWRPNVLKFSHNLLEELRPRAITRDLDWGIRVPVEGWQDNPMKSIYVWFDAVIGYLSASIEWARRIGRPDAWREFWNDEDARSYYFMGKDNIVFHSVIWPGILLGTNGRGDKGGEPSEELGTLNLPTEIVSSEFLTMSGSKVSNSRGATIFVGDFLHEFGPDALRYFIAVAGPENQDTDFTWEEFVRRVNFELANEWGNLVNRSISMAFKNCHEIPAAGELTDADRELLDAAAAGFDTVGGLLAHARFKAAITEAMRIVGLANAYISAEEPWKLKDNPERRDTVLHVALQVVSDVNTMMTPFMPHSAQKIYEALGGEGVWAAQPELIETDGAPILMGDYATEQASWGRHEITVGTPLSKPSPIFRKLDAKLAQTGPQWAPVNPQ
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_STUST
Sequence: MSADFLALAVPGVQKLSPYVTGKPIDELARELGIEPARIVKLASNENPLGPNPRVLEAVRGELSELTRYPDGSGFRLKAKLAERFGLKSEQITLGNGSNDIIDLVARCCGAGPNAVFSAHAFAAYPLCTQAAGAESRVVPAVDYGHDLDGMLKAIDEQTAVIFIANPNNPTGNLVRAQALESFLDRVPERVLVVLDEAYIEFYRGTNCQRLNYLVRYPNLLVSRTLSKVYGLAGLRVGYSASSPQIADVLNRVRQPFNVNSLALVAACAGWMTSSIWLKGGGWIAPVWELEQGLAELRLKWIPSRGNFLAVDLGRDAAPINAGLLRDGVIVRPIAGYDCPTFLRVSIGTEQENARFLEALRVVLDQ
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: MNMA_ECOHS
Sequence: MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USPG_SHIFL
Sequence: MYKAIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSASLSLHRFAADVRRFEEHLQHEAEERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAEELGADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR
What are the official names of this protein?
Universal stress protein G.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: Y1698_LACJO
Sequence: MQKNQIVDLEITDLSYEAMGVAHLDGMTVFVNNALPGEIVSAKLLKVKKNFAFAKIEKIKKESPDRINVKLRQWVQTGLASLAHIKYDKQLEFKRNQVVNLLHKADLDNVKVGQTMPSPEETGYRNKAQVPVREVNGKLDIGFFRKHSHDLVPLTSFFTTDPEIDRVLIKVRDILRKNHVPAYDEIHNKGEVRYLEVRRSKATGEIMVILVCLHKDFPQLKEVTKEISEIKGVTSVVLNHNPKKTNVILGKKDYLLWGEPQITDKIGDVSFKISPQSFFQINSLQTPRLYDLAIQKADLKPDDVVIDAYSGIGTIGLSVAKHVKAVRGMEVIEPAVEDANANAKLNGITNAEYVVGKAEEVMPRWAKEGLKTDVIFVDPPRKGLTPEFIDAAVETNPKKIVYISCNPATMVRDLQLFKEQGYDFDEIDPVDMFPQTPHVEAVAVLERTEK
What are the official names of this protein?
Uncharacterized RNA methyltransferase LJ_1698.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: BRKRN_SYLVI
Sequence: MFTMKKSLLLLFFLGTISMSLCEEKRDADEEETEGEAKMEDIKRAEAVPPGFTPFRKP
What is the function of this protein?
Induces contraction of intestinal smooth muscle in isolated guinea pig ileum.  May induce relaxation of arterial smooth muscle.  May target bradykinin receptors (BDKRB).  Lacks antibacterial activity against the Gram-positive bacterium S. aureus and the Gram-negative bacteria E. coli and B. dysenteria, and antifungal activity against C. albicans.
What are the official names of this protein?
Ranakinin-N.
What is the protein family that this protein belongs to?
Belongs to the bradykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_CAUSK
Sequence: MTERTFSIIKPDATRRNLTGKINAVIEEAGLRIVAQRRVKLTDAQAKKFYEVHAERPFYGELVAQMTAEPVVVQVLEGDNAVLKYREVMGATNPDNADEGTIRKLFALSIGENSVHGSDSLENAAIEIAQFFKDEDIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_BACC2
Sequence: MENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEDIDLPPVKRNPAQDDSAHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINGILK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.