PharMolix/UniProtQA huggingface dataset:
Protein: NDHJ_CERDE
Sequence: MQGRSSAWLVKHELVHRSLGFDYQGIETLQIKPEDWYSIAVISYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIQYGVDQPEEVCIKVFAPRGNPRIPSVFWIWKSADFQERESYDMFGISYDNHPRLKRILMPESWIGWPLRKDYIAPDFYEIQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RL23_HALHL
Sequence: MNQERLYTVLRGPHISEKSTVIADGAGQVVFQVAPDANKKEIKAAVEKLFDVQVTGVRTVNAKGKRKRFGMIRGRRRDWKKAYVTLAEGQDIDFLGGE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RUVB_STRPC
Sequence: MARILDNDVMGNEEFSDRTLRPQYLREYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTRAGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CP51_CANAL
Sequence: MAIVETVIDGINYFLSLSVTQQISILLGVPFVYNLVWQYLYSLRKDRAPLVFYWIPWFGSAASYGQQPYEFFESCRQKYGDVFSFMLLGKIMTVYLGPKGHEFVFNAKLSDVSAEDAYKHLTTPVFGKGVIYDCPNSRLMEQKKFAKFALTTDSFKRYVPKIREEILNYFVTDESFKLKEKTHGVANVMKTQPEITIFTASRSLFGDEMRRIFDRSFAQLYSDLDKGFTPINFVFPNLPLPHYWRRDAAQKKISATYMKEIKSRRERGDIDPNRDLIDSLLIHSTYKDGVKMTDQEIANLLIGILMGGQHTSASTSAWFLLHLGEKPHLQDVIYQEVVELLKEKGGDLNDLTYEDLQKLPSVNNTIKETLRMHMPLHSIFRKVTNPLRIPETNYIVPKGHYVLVSPGYAHTSERYFDNPEDFDPTRWDTAAAKANSVSFNSSDEVDYGFGKVSKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILTTFVYNLRWTIDGYKVPDPDYSSMVVLPTEPAEIIWEKRETCMF
What is the function of this protein?
Sterol 14alpha-demethylase that plays a critical role in the third module of ergosterol biosynthesis pathway, being ergosterol the major sterol component in fungal membranes that participates in a variety of functions (PubMed:8647850, PubMed:9559662, PubMed:10393548, PubMed:28258218).  The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane (By similarity).  In filamentous fungi, during the initial step of this module, lanosterol (lanosta-8,24-dien-3beta-ol) can be metabolized to eburicol (By similarity).  Sterol 14alpha-demethylase catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of both these sterols in the form of formate, and converts eburicol and lanosterol to 14-demethyleburicol (4,4,24-trimethylergosta-8,14,24(28)-trienol) and 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol, respectively, which are further metabolized by other enzymes in the pathway to ergosterol (PubMed:8647850, PubMed:10393548, PubMed:28258218, PubMed:9559662).  Can also use susbtrates not intrinsic to fungi, such as 24,25-dihydrolanosterol (DHL), producing 4,4-dimethyl-8,14-cholestadien-3-beta-ol, but at lower rates than the endogenous substrates (By similarity).
What are the official names of this protein?
Lanosterol 14-alpha demethylase, LDM, Cytochrome P450 51, Cytochrome P450-14DM, Cytochrome P450-LIA1, CYPLI, Ergosterol biosynthesis protein 11, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: AACS_MOUSE
Sequence: MSKLARLEREEIMECQVMWEPDSKKDTQMDRFRAAVGTACGLALGNYNDLYHWSVRSYMDFWAEFWKFSGIVYSRMYDEVVDTSKGIADVPEWFRGSRLNYAENLLRHKENDRVALYVAREGREEIVKVTFEELRQQVALFAAAMRKMGVKKGDRVVGYLPNSAHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHGHLEKLQRVVKGLPDLQRVVLIPYVLPREKIDISKIPNSVFLDDFLASGTGAQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHMLHGNMTSSDILLYYTTVGWMMWNWMVSALATGASLVLYDGSPLVPTPNVLWDLVDRIGITILGTGAKWLSVLEEKDMKPVETHNLHTLHTILSTGSPLKAQSYEYVYRCIKSSVLLGSISGGTDIISCFMGQNSSIPVYKGEIQARNLGMAVEAWDEEGKAVWGASGELVCTKPIPCQPTHFWNDENGSKYRKAYFSKFPGVWAHGDYCRINPKTGGIIMLGRSDGTLNPNGVRFGSSEIYNIVEAFDEVEDSLCVPQYNRDGEERVVLFLKMASGHTFQPDLVKRIRDAIRLGLSARHVPSLILETRGIPYTLNGKKVEVAVKQVMAGRTVEHRGAFSNPETLDLYRDIPELQDF
What is the function of this protein?
Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity).  Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (PubMed:22985732).
What are the official names of this protein?
Acetoacetyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL16_BART1
Sequence: MLQPKRTKFRKQFKGRIHGVAKGGTDLNFGAYGLKAVEPERVTARQIEAARRAITRYMKRSGRVWIRIFPDLPVTSKPTEVRMGKGKGSVDYWAARVAPGRVMFELDGVPEDVAREALRLGAAKLPIKTRFIQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL22_POLNS
Sequence: MMMEVKAIHKGARISAQKTRLVADQIRGLPIARALNILNFSPKKAAFIVKKVVESAVANAEHNKGADIDELKVSAIIVDKGTSLKRFTARAKGRGNQIEKQTCHISVTLSN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: AEE21_ARATH
Sequence: MEGTMRCSANYVPLSPISFLERAAVVFGSRTSVVYGDIQYTWHQTRDRCVRLASALSDLGLSRHDVVAALAPNVPALCELYFGAPMAGAVLCVLNTTFDSQMLAMALEKTKPKVFFVDSEFLSVAEESLSLLSNIEEKPLIITITENPTEQSKYEQYEDFLSTGNPNFKPIRPVDECDPIALNFTSGTTSTPKCVVYSHRGAYLNATAVGVMNEMKPMPVYLCTVPMYHCSGWCYIWTVTAFGGVIVCLREVNDEVIFDSIVKHKVTNFGGSPPVLNMIANARDSVKKSFPWTVQVMSGGSSPPEVMLKLKKLGFKVMMAYGCSEVYGLGTACLWMPEWETLPEEESLRLKARDGLNHFAKEAVDVLDPTTMKSVPHDGKTIRVIALRGNTVMSGYFKDKEATEAAFRGGWYWSRDMGVIDPDGYIQFKDRSQDVITCGGEIVGSKEIEGILYSHPAVYDAGVVGRPDETLGESMCAFVKLKEGAEAREEEIIEFCKRKLGNKNMKMIPKTVVFSDVPKTPTGKIRKNVLRKMAKDMGYVQLRAVE
What is the function of this protein?
May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs.
What are the official names of this protein?
Probable acyl-activating enzyme 21.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: GPDA_DECAR
Sequence: MKITLLGAGAWGTALSIAFSGKHDLTLWSREVDVADDLRKTRENHRFFPGYKLPESVAVSTDFEVAVAGAELLVVATPIAGLRPTVERLQALGCKLPVLWVCKGFEAGSGKLPHQVVAEVLGKEALCGALSGPSFAEEVAAGQPTAVSLATNDPAFAREAARQLHTTRLRIYANDDLVGVEVGGAVKNVLAIATGVCDGLGLGLNSRAALMTRGLAEIARLGLALGAERQTFMGLAGMGDLILTCTGDLSRNRRVGLALAQNKSLPQILEELGHVAEGVYTAREVDRLAARLGVEMPISAAVAAVLDGRLTAAQAVEQLMARDPKEELA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_BRADU
Sequence: MTANRKELAVERAAKKEAVEQLNGVFKTTSVAVVAQYSGLTVAQMQKLRQQMKQAGASVKVSKNRLAKIALEGTDVVAIGPMLKGPTVIATSNDPVAAPKVAIEFAKANEKFVIVGGSMGKTVLNVDGVKALASLPSLDELRGKIVGLIVAPATKLAQLANAPAGKLARVIQAHASKGEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MSL4_ARATH
Sequence: MAVDSTDQRRDFVVRIDGEDNGDSEKFWRESSINFWHNDKSSKPPGGEEDDGSFDFMRRSSEKSEEPDPPSKLINQFLNKQKASGDEISLDMEANMPELQKNTVPPLSSTAVSGSASPVTAPVTASYRNGTGDAIRRRQNRVTLSPSVKDGDSSEDEENRVDGSEVVKCTSNRSTMRTKTLMKMKTRSRLMDPPTPTYPDMVSGRTPRSGNLNPGFSGRNTKPGTPNQGGSKDLEEEEDPFSEEDLPEGLRKEKICVWVIIEWIFLILIIASLICSLVIPYLRGKTLWDLALWKWEVMVLVLICGRLVSSWIVKLFVYFVESNFLWRKKVLYFVYGIRKPVQNCLWLGLVLIAWHFLFDKKVEREMRSTVLKYVTKVLICLLVAVIIWLIKTLLVKVLASSFHMSTYFDRIQESLFTQYVIETLSGPPRIEIHIEEEKVANDVKTFEIVGRKLSPLGPKAVSSPPQVTVGSGRLQKSPSRVGKSPVLSRSGSKKEGGEEGIRIDHLQRMNTKNVSAWKMKKLMNVIKKGTLSTLDEQIQDTTTQEDDKATQIRSEFEAKLAARKIFQNVAEPGSRYIYMEDFMRFLSEDESERAMDLFEGASECHKISKSCLKNWVVNAFRERRALALTLNDTKTAVNRLHRIVDVLVSIVILIIWLLILGIATTKFLLVISSQLLLVVFVFGNSCKTIFEAVIFVFVMHPFDVGDRCEIDGVQMIVEEMNILTTVFLRFDNQKIVYPNSLLGTKPIANYYRSPDMQDAIEFFVHIATPPEKTTALRQRILSYVDNKKDHWHPSPMIVFRDMCGLNSVKIAMWPTHKMNHQNMGERYVRRGQLLEEIGRLCRELDIEYRLYPLNINVKSLPAATPITSDRIPPSWNQQRSV
What is the function of this protein?
Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer.
What are the official names of this protein?
Mechanosensitive ion channel protein 4, Mechanosensitive channel of small conductance-like 4, MscS-Like protein 4.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RNY_CLOPS
Sequence: MVVGILIGIIILGVVGFIQYTLIEKASKNRVESLEKEASLALEEAKREAESTKKEAILEAKEEVHKLRSDLDKEIRDRRNEIQRFERRLIQREESLDKKGEMLEKREDSINKKSIEIQELEERVQSLYGEQRAELERISNLSSEDARTLLLDEVRREIKHESAMLIKELETKAKEEADKKSREIITNAIQRCAADHVSETTVHVVALPNDEMKGRIIGREGRNIRTLETLTGVDLIIDDTPEAVILSSFDPIRREVARIALEKLIVDGRIHPARIEEMVERAIKDVENDIKEEGEQATFETGVHGLHPEIIKLLGRLKYRTSYGQNVLKHSIEVSYLAGLMASELGLDVNLARRAGLLHDIGKGVDQEYEGPHAVIGGELAKKYHESPAVVNAIAAHHGDTEMQTLEAVLVQAADAISAARPGARRETLEAYIKRLEKLEEIATSYEGVEKSYAIQAGREIRIMVKPDQVDDAGAIEMARNIVKKIEEQLEYPGQIKINVIRETRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CITX_ECOSM
Sequence: MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGDILSRRDYSLPPRRCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
What is the function of this protein?
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.
What are the official names of this protein?
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, Apo-ACP nucleodityltransferase, Holo-ACP synthase, Holo-citrate lyase synthase.
What is the protein family that this protein belongs to?
Belongs to the CitX family.
Protein: PA2AC_CALRH
Sequence: MRTLWILAVLLVGVEGSLVQFETMIMKLAKRSGFFWYSFYGCYCGWGGHGLPQDPTDRCCFVHDCCYGKVTNCNPKTATYSYTEENDGIVCGGDDPCKKQVCECDRVAAMCFRDNKDTYDGDKYWKLPPQKCQEDPEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits ADP-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Acidic phospholipase A2 S1E6-c, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARLY_BRASO
Sequence: MSNKMWGGRFTERPDEIMEDINVSIDVDRHLYAQDIAASKAHAAMLAAQGIITSGDAKNMARGLDTILSEITKGSFEFKRALEDIHMNVESRLSELIGPAAGRLHTARSRNDQVATDFRLFVRDEIDDIDAALAAYQQALATRALEFAGTVMPGFTHLQTAQPVTFGHHLLAYVEMAGRDRGRFADARERLNESPLGAAALAGTSFPIDRHATAQALGFDRPMANSLDAVSDRDFVLETLSAASICAVHLSRFAEEIVIWTSPLVGLIKLSDKFTTGSSIMPQKRNPDAAELVRAKTGRVIGALNGLLIVMKGLPLAYQKDMQEDKQGAMEAFAALSLAIRAMTGMALDLVPDEARMKAAAGEGYATATDLADWLVRTLKMPFREAHHVTGRIVALASKQGVALHELPLEAMQEVEPKITADVLGVLSVEASVKSRTSFGGTAPKNVASQAKAWLKRLEKQRK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_ALKEH
Sequence: MERRADAATGKRPIRSFVRREGRLTAGQQRALELLWPAFGLERPPAGQPLDLDRAFGRRAPRILEIGFGNGESLAEQAATHPERDYLGIEVHRPGVGHLLMEVEKRHLGNVRVMMADAAEVLAHHIPDGSLHGVQLFFPDPWPKKRHHKRRLVQPQWVRAVAAKLAPGGFLHLATDWADYAEHMLDVLEAEPDLENTCGPRQFSPRGERPETKFERRGLRKGHQVFDLYYRKREHPG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: LFTR_RHILW
Sequence: MAGSRRKSPGITPEILLRAYSIGLFPMAESADDPEIFWVEPELRGVLPLDHFHLSKSLAKTVRRKPFEIRFDHAFDSVIAACAEETSGRPSTWINKTIRSLYATLFDMGHAHTVEAWDGDKLVGGLYGVSLGSAFFGESMFSRRTDASKICLVHLVERLRERGFTLLDTQFTTEHLKTFGAIDVAKADYAVMLAAAMQSPHLKF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJJB_ECOUT
Sequence: MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HNF1A_HUMAN
Sequence: MVSKLSQLQTELLAALLESGLSKEALIQALGEPGPYLLAGEGPLDKGESCGGGRGELAELPNGLGETRGSEDETDDDGEDFTPPILKELENLSPEEAAHQKAVVETLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHAGQGGLIEEPTGDELPTKKGRRNRFKWGPASQQILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEVRVYNWFANRRKEEAFRHKLAMDTYSGPPPGPGPGPALPAHSSPGLPPPALSPSKVHGVRYGQPATSETAEVPSSSGGPLVTVSTPLHQVSPTGLEPSHSLLSTEAKLVSAAGGPLPPVSTLTALHSLEQTSPGLNQQPQNLIMASLPGVMTIGPGEPASLGPTFTNTGASTLVIGLASTQAQSVPVINSMGSSLTTLQPVQFSQPLHPSYQQPLMPPVQSHVTQSPFMATMAQLQSPHALYSHKPEVAQYTHTGLLPQTMLITDTTNLSALASLTPTKQVFTSDTEASSESGLHTPASQATTLHVPSQDPAGIQHLQPAHRLSASPTVSSSSLVLYQSSDSSNGQSHLLPSNHSVIETFISTQMASSSQ
What is the function of this protein?
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity).  Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (PubMed:12453420, PubMed:10966642).  Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity).
What are the official names of this protein?
Hepatocyte nuclear factor 1-alpha, HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1.
What is the protein family that this protein belongs to?
Belongs to the HNF1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCKA_ASHGO
Sequence: MSPSKVYQTPEEKIRAELGLSSGVLTIRRNAPAAVLYEDALAERKTAISSTGALIAYSGEKTGRSPKDKRIVDEPTSSDNIWWGPVNRKASEKTWLINRERAADFLRTREHLYIVDAYAGWDPRYRIKIRIVCCRAYHALFMTNMLIRPTEEELAEFGEPDFTVWNAGQFPANTHTEGMSSKTTVEINFRAMEMVILGTEYAGEMKKGIFTVMFYLMPINHNVLTLHSSANQGPNNDVTLFFGLSGTGKTTLSADQHRKLIGDDEHCWSDYGVFNIEGGCYAKCIGLSGEKEPEIFNAIKYGSVLENVVYDPVTRVVDYEDSSITENTRCAYPIEYIPSAQIPCLSENHPSNIVLLTCDASGVLPPVSRLTPEQVMYHFISGYTSKMAGTEQGVTEPEATFSSCFGQPFLALHPMKYATMLAEKMSQHNASAWLINTGWTGSSYTAGGKRCPLKYTRAILDSIHDGTLAQAEYETLPVFGLSIPKAVEGVPAELLNPAKNWVEGEGKYASAVSALASKFTENFKIYQDQATEEVVRAGPQI
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP).
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
Protein: CSRA_PASMU
Sequence: MLILTRKVGESLLIGDDISITILNIRGNQVKIGIKAPKDVSVHREEIYQRIKQALEAPHVGE
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_AZOPC
Sequence: MRQIVLRGMGVALITPFKCDGTVDYPALSYLVDYQLQNGIDYLIVLGTTAETPTLSYEEQKEIVRLVVSIVRERIPIVVGVGGNNTQAVIHKLNTEDFGKIDAILSVVPYYNKPTQDGIYQHFKYIAQATSLPIILYNVPSRTGVNMTAETSLLLANDFENIVAIKEASGNIDQIGVIIENKPSGFQVLSGDDELSLSLIGIGAVGVISVIGNVFPKEFGKMIRLALNGDSDNARIIHGQFAELFELLFIEGNPAGVKGMLNVMGFIENKLRLPLVPVLEATYERIKKALLMFRTQ
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPHB_METBF
Sequence: MLTFIGLGLFDEYDISLKGLEAIREADMVYAEFYTSCLMGTNLEKMEKLYGKKVFLLSREDVEQHPDWLSKAKNRNLCFLTGGDTMVSTTHVDLRLRAEKLGIDTRLIHGASIASAVSGLTGLQNYRFGKSASIPHPYESRRGTRIISETPYDTIKQNLELGLHTLVFLDIDKEKGYMTVNTALELLLEVEEKRGEGIMRGAAAVGIARAGSEKPVIRADYAENLKDFNFGKPLHILVIPGKLHFLEAEALVKLAGGPVGFMKEVE
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: Y3078_ARATH
Sequence: MAEIKNAKVEQRQTKIRNVPVAVTPEGFWCCPSPVAFQKTLKSHNSLTKHKQSSPALQPPKPEKKPSSTTIRSVIASDETQQNLGSFDTVHSIAVPATVQERPQRQKVETLPRKVAIEFGEPGSSDAKVILVGKQGFCVKLSVHKKVLVDHSCFFAKKLAEKDSVFACLEIESCEDAELYVETIGLMYCKDMKQRLMKQNVSRVLRVLKVAELLGFSSCIQSCLDYLEAVPWVGEEEEEKVISSILRLKTEGVGVTPVLKRVASNAVDPPKETLSRIIELVLRSKEEKSRREMKSIVLKLLREQNGANVADNFNDTIYSSCQTCLDSVLSLFKQASEGEKPETDTKQIAVEADNLTWLLDVLAERQAAEEFSVTWANQKELALLHEKLPLMSRYHISRVTSRLFIGIGRGELLPSKDTRLLLLTTWLQPLFNDYNWLQHGCRSFDGKLVEEGIGRTILTLPLEDQQSILLSWLGSFLNGGDGCPNLQRAFEVWWRRSFIRPYSDRQANGSCQTDSTSKEE
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At3g50780.
Protein: YPF07_PLAF7
Sequence: MENISVLTNNNMSVKNLNPYNNNDEEKQNSDVLNQERNSTNDLFSSFYEKFNDIFLFIEDTTKNNNCLEDEVDDNLIKTLYNLCELFLNYMKNINDFANFKISQQDQELIIHSYENFVRQCKEYNDKPKVKQLENEISNLLDLLFNNTSEAVNTLFSADSFFMDHVENLKLKMSEKNQKIQFENERLKKLELEKQVEQFDESFEANKKKNNEMDETINKLKKDINKLNEKIEKYDNFMKMKRKEIDIDFSDTLDCKERIKLLENCIKTTERNMKTTQLAPLKIVENCADYIIFEFMTTRNLMRFKVSNYESDNVHIEINPYEENILAYINKNVKKCKDISEISYLIKEAIYLNFLDL
What are the official names of this protein?
Uncharacterized protein PF3D7_1446700.
Protein: QUEF_SALG2
Sequence: MSSYENHQALDGLTLGKSTDYRDNYDASLLQGVPRSLNRDPLGLTADNLPFHGADIWTLYELSWLNSQGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQTRFDTWETVRQTLERDLRACAQGNVSVRLHRLDELEGQPVAHFHGTCIDDQDISIDNYQFTTDYLQHAVSGEKQVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRKIDREKLLRYLVSFRHHNEFHEQCVERIFNDILRFCQPETLSVYARYTRRGGLDINPWRSNTDFVPATGRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.