PharMolix/UniProtQA huggingface dataset:
Protein: CCN1_CHICK
Sequence: MGSAGARPALAAALLCLARLALGSPCPAVCQCPAAAPQCAPGVGLVPDGCGCCKVCAKQLNEDCSRTQPCDHTKGLECNFGASPAATNGICRAQSEGRPCEYNSKIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPSPRLVKVPGQCCEEWVCDESKDALEELEGFFSKEFGLDASEGELTRNNELIAIVKGGLKMLPVFGSEPQSRAFENPKCIVQTTSWSQCSKTCGTGISTRVTNDNPDCKLIKETRICEVRPCGQPSYASLKKGKKCTKTKKSPSPVRFTYAGCSSVKKYRPKYCGSCVDGRCCTPQQTRTVKIRFRCDDGETFTKSVMMIQSCRCNYNCPHANEAYPFYRLVNDIHKFRD
What is the function of this protein?
Probable secreted regulatory protein.
What are the official names of this protein?
CCN family member 1, Cellular communication network factor 1, Protein CEF-10, Protein CYR61.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted.
Protein: NPS3B_HUMAN
Sequence: MLVLRSGLTKALASRTLAPQVCSSFATGPRQYDGTFYEFRTYYLKPSNMNAFMENLKKNIHLRTSYSELVGFWSVEFGGRTNKVFHIWKYDNFAHRAEVRKALANCKEWQEQSIIPNLARIDKQETEITYLIPWSKLEKPPKEGVYELAVFQMKPGGPALWGDAFERAINAHVNLGYTKVVGVFHTEYGELNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPASFSPLK
What are the official names of this protein?
Protein NipSnap homolog 3B, NipSnap3B, SNAP1.
What is the protein family that this protein belongs to?
Belongs to the NipSnap family.
Protein: DLTC_LACJO
Sequence: MDTKQAVLDILNELTGEDLSDQMDENIFENGLLDSMATVQMLLELQDKCDVTAPVSEFHREDWDTPNKIIAKVESLRNE
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSUN3_BOVIN
Sequence: MVLTLLKAKPERKLAKQICKVVLDHFEKQYSKELGDAWNTVRDILTSPSCWQYAVLLNRFNYPFELEKDLHLKGYHSLLQGSLPYYPKSMKCYLSRTPHRMPSERHQTGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAAPGGKSLALLQCAYPGYLHCNEYDSLRLRWLRQTLESFIPQPLVNVIKVSELDGREMGDAQPETFDKVLVDAPCSNDRSWLFSSDSQKAACRISQRRNLPLLQMELLRSAIKALRPGGLLVYSTCTLSKAENQDVISEVLNSYSNIMPVDIKEMARTCSRDFTFAPTGQECGLLVIPDKGKAWGPMYVAKLKKSWTT
What is the function of this protein?
Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt-tRNA(Met).  mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5-formylcytosine (f(5)c) at this position.  mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation.
What are the official names of this protein?
tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial, NOL1/NOP2/Sun domain family member 3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RAC7_ARATH
Sequence: MSASKFIKCVTVGDGAVGKTCMLICYTSNKFPTDYIPTVFDNFSANVAVDGQIVNLGLWDTAGQEDYSRLRPLSYRGADIFVLAFSLISKASYENVLKKWMPELRRFAPNVPIVLVGTKLDLRDDKGYLADHTNVITSTQGEELRKQIGAAAYIECSSKTQQNVKAVFDTAIKVVLQPPRRKEVPRRRKNHRRSGCSIASIVCGGCTAA
What is the function of this protein?
Acts as a negative regulator of abscisic acid (ABA) responses.
What are the official names of this protein?
Rac-like GTP-binding protein ARAC7, GTPase protein ROP9.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: LPXK_MARMM
Sequence: MKEPAFWRTDGGRGSGALARALLAPLGWIHAWAVARRIRKATPVRIGPKVVCVGNLTVGGTGKTPVTQTLMQRLAEMDLTAASLSRGYGGREAGPLRIDPATHDASTVGDEPLLLARTGQAWIARDRAAGGRAIEAAGGVDLVLMDDGHQNPDLAKDCSIVVVDGLTGWGPGTIVPAGPLREPVATGLARADAVIVMMPDAATEPDWTGLGLSDLSIPVFHAWLEPLAPPPAGKLVAFAGIGRPEKFFDALRAAGGDIGEVAVYGDHHAFNAGDLRHLDALAAAHDAQLITTEKDWVRLPVDIQARVTAWPVRAVFANPGALDGLLRDVMDADMDAGGEAG
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: PPNP_YERPB
Sequence: MLKFNEYFTGKVKSIGFDSDSIGPASVGVMEKGEYTFSTAKAEEMTVITGSLKVLIPGSPDWQTFMPGETFYIPGESEFNLQVAEASSYLCKYLS
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: KAD_STRP7
Sequence: MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMVNQTEMGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLAELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDKPETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIX_HALSA
Sequence: MQALVIVGHGSHLNPGSSEPAYTHADTIRESGAFDEVREAFWKEEPSFRNVLRTLESDEVYVVPLFISEGYFTEQVIPRELRLDDFDPDDWDSDGTDADHVTLEADDVEKTIHYCGPVGTHDSMSEVIVQRASSVTGREEFGDDFGLAVVGHGTERNENSAKAIYYHADQIREMGVFGEVQAVFMDEDPEVDDVTDFFDTDDIVVVPLFVSDGFHTQEDIPEDMGLTDDYRTGYDIPTAVDGHDIWYSGAVGTEPLAADVVLERAADAGAPVGDAVDAVREQTRGANAAAGD
What is the function of this protein?
Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis.
What are the official names of this protein?
Probable sirohydrochlorin cobaltochelatase, CbiXS.
What is the protein family that this protein belongs to?
Belongs to the CbiX family. CbiXS subfamily.
Protein: GCSH4_DICDI
Sequence: MNKIISNKIINNNIIFRNNFNNLFFIRNFINNKNNNNNNNNNNNNNNNNNNRNKKLKYSPNHQWIKISENKDFATIGITNYVSDIVNNEFNKILKIKLPKINDKIRLNQPFLSIWTKEEENIQFKSPLSGIVSKVNNKFNNQQTTTISTKTTTTTTKIKPKLPLKSNSLFFNNDQDSWTIELKINEPFQTNHLMTEEEYAHYCENTDYK
What are the official names of this protein?
Glycine cleavage system H-like protein gcvH4.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: KRA59_HUMAN
Sequence: MGCCGCSGGCGSSCGGCDSSCGSCGSGCRGCGPSCCAPVYCCKPVCCCVPACSCSSCGKRGCGSCGGSKGGCGSCGCSQCSCCKPCCCSSGCGSSCCQCSCCKPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPCCSQSRCCVPVCYQCKI
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 5-9, Keratin, cuticle, ultrahigh sulfur 1, Keratin, ultra high-sulfur matrix protein A, Keratin-associated protein 5.9, UHS keratin A, UHS KerA, Ultrahigh sulfur keratin-associated protein 5.9.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 5 family.
Protein: PSBJ_COFAR
Sequence: MADTTGRIPLWIVGTVTGILVIGLIGVFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL6_YERPG
Sequence: MSRVAKAPVVIPAGVEVKLNGQVISIKGKNGELTRTVHSAVEVKQEENTLTFAPREGAVDGWAQAGTTRALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLALGFSHPVDHELPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NQRB_YERPE
Sequence: MGLKNFLEKIEHHFEAGGKLEKYYPLYEAAATIFYTQGKVTPGASHVRDAIDLKRMMILVWFAVFPAMFWGMYNVGYQAIPALNQLYSGAELQQVIAGDWHYRLAQMLGASLTPDAGWASKMLLGAAYFLPIYAVVFLVGGFWEVVFSIVRKHEINEGFFVTSILFSLIVPPTLPLWQAALGISFGVVIGKEIFGGTGRNFLNPALAGRAFLFFAYPAQISGDLVWTSADGFSGATPLSQWSVNGSHSLVNTVSGQPITWMDAFLGYIPGSIGEVSTLMILIGGAIIIFGRVASWRIVAGVMIGMIATAYLFNWIGSTTNPLFAMPWYWHLVLGGFAFGMIFMATDPVSASFTNKGKWWYGGLIGVMCILIRVANPAYPEGMMLAILFANLFAPLFDYVVVQANIKRRKARGE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HXC6B_DANRE
Sequence: MNSYFTNPSLSCHLNSGQEVLPSVAISSTNYDPVRHFSPYGAAVAQNRIYSNPFYSHQENVMFGSSRPYDYGSNMFYQDKDVLPSCRQGFGQTQGSLTQDYASDQGKTVEPKGVVQIYPWMQRMNSHRVGYGSDRRRGRQIYSRYQTLELEKEFHYNRYLTRRRRIEIANTLCLSERQIKIWFQNRRMKWKKESNLTSILNDNGSVGAGQDTDKEETGETAEKDEHD
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C6b.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASCL1_ORYSJ
Sequence: MGVAAAAGRLLAAVDWEREAYPAYRDFFALPLFAVFFLVVRYLLDCFVFEWIGRKLIFGKEKVDYEKEETRKKIRKFKESAWKCVYFLSGEILSLSVTYNEPWFTNTKYFWVGPGDQVWPDQKIKWKLKAVYMYAAGFYTYSIFALMFWETRRSDFGVSMSHHVATVALIVLSYVFRFARVGSVVLAIHDASDVFLEVGKMAKYSHCDLLANVAFLLFVVSWVLLRLTYFPFWILRSTSYEVLLTLDKKKHNFDGPIYYYVFNSLLFSLLVLHIYWWVLIYRMLVRQIKTRNVGDDVRSDSEGEDEHED
What is the function of this protein?
Mediates resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis.  Could salvage the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in ceramides-depleted cells after SAM exposure (By similarity).
What are the official names of this protein?
ASC1-like protein 1, Alternaria stem canker resistance-like protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: COBS_SHEON
Sequence: MSERESWHKEIDLFFVAMGYFTRIPMPKWVEVDADKLNKASRYFGLVGLLVGLLSAIIFWLTQNWLPAGVSVLLSMLTGILLTGGFHEDGLADTFDGFGGGWTAEDKLRIMKDSRLGSYGALALIMVLLLKWQLLVELALYDPVVAGSAMIVAHTVSRVVAASLIFTETYVRDDETSKSKPLAQHQGINDLFILIASGVLVLLVLKGIAALSLLLVMIGLRRLIVVIFRRQIGGYTGDTLGAAQQICEIVCYFVLLVVGGIL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_ECOLU
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PRLD2_HUMAN
Sequence: MGVSVDVHQVYKYPFEQVVASFLRKYPNPMDKNVISVKIMEEKRDESTGVIYRKRIAICQNVVPEILRKSLSTLVILCWKKVSILKVPNIQLEEESWLNPRERNMAIRSHCLTWTQYASMKEESVFRESMENPNWTEFIQRGRISITGVGFLNCVLETFASTFLRQGAQKGIRIMEMLLKEQCGAPLAE
What are the official names of this protein?
PRELI domain-containing protein 2.
Protein: HIS3_CHLT3
Sequence: MKESEGIDVKLMDIVRFDKNGLIPAITQDYETGKVLMLAYMNKESLEVTLKERKACYWSRSRQELWLKGATSGNFQEVMQISIDCDADAILLKVKQKGGACHVGYYSCFYRQVENDNSSLSICDKLVFDAEEVYGKSNKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLPHP_MYCTU
Sequence: MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRLGCRSVGESREQEASAKMAELNRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGSTCVRVGTALLGPRRLRSP
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
Protein: UREE_CORGL
Sequence: MIITAIDTNIYDQPEFVEGRDVIGVRFEDLVLDKRIQRVALPGGEELGLRLNHGHPILREGDVLKADDKTVFVVEIIPTDVLVITPSDIHQMGFVAHSLGNRHLPAQFSKPGELTEKAAMIVQYDHTVVSFLDEHGIEYQRTELVPPIPFRHSGHTH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_XANOM
Sequence: MSASTAAPARDRLRIAIQKSGRLAEPARSLLAACGLSWRQSRDKLFCYGESLPVDLLLVRDDDIPGLIADGVCDLGIVGQNELEEQAAERRGNGLPAAYHAVRGVGFGQCRLMLAVPEEWDWQGVAQLAGKRIATSYPAILADWLERQGIEATVVELSGSVEIAPRLGTADLICDLVSSGATLAANQLKPVELVMESEAVLAGAVREPADARAGLLAMLLRRMDGVLKLRDSKLLMFRADQDNVDALRRLLPDADPLVQLPDDGNGVLRLQTMCHGAVTWQRLEELERAGAQGLMVLTVERSLA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCES_ASPOR
Sequence: MADENPQAQGAEGGGKGKSSSMRLQERHQQLRKRGRTPPSAYARRDMNETAQQHNRNESSNRSPSPLAPPRSPSPDAQARKRKRPGGGARMGLVDRETLRRRQEERERSQQEEAMRFSQNRGVTDIVRHHYNAVPQRGREWRKTESKIKGLRSFNNWIKSTLIQKFSPDEEFVARSIGTKDWADETAPPPMEDKRLLVVDLGCGKGGDLGKWQLAPQPVDLYVGLDPAEVSIVQARERYNGMRTGRGPRGRRGPLFHAEFAPKDCFGEYLGDVPIVQQVGIDPNAGPGGSVMSSRWGGGGFDVVASMFTIHYAFESEEKARQMLRNVAGCLKKGGRFLGVCPNSDIISARVAEMNAKRKERETAAKKEEAEPEDGEVEEDDNKIEWGNSIYRVRFSGDTPEDGIFRPPFGWKYSYFMEEAVEEIPEYVVPWEAFRALTEDYNLELQYRKPFLEVWKDEKDDQELGPLSERMGVRDRNTGALLMTEEEKEAASFYHAFCFYKV
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSPM_BACSU
Sequence: MKTRPKKAGQQKKTESKAIDSLDKKLGGPNRPST
What are the official names of this protein?
Small, acid-soluble spore protein M, SASP M.
What are the subcellular locations of this protein?
Spore core.
Protein: RNZ_STRPD
Sequence: MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKMVQDLEEVII
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RNPA_SHEB8
Sequence: MTSYTFSRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNTEQHPRMGLTVAKRFVKRANQRNRIKRVIRDSFRLNQHDIPHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RUVB_HISS2
Sequence: MIEVDRIVSANAKVDDEYIDRAIRPKLLSDYIGQPQVREQMEIFIQAAKLRQDALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYSVEDLASIVTRSAVCLQLEIDVEAGQEIACRSRGTPRIANRLLRRVRDYADVKNGGKITALIAQEALKMLDVDLAGFDFMDRKLLQAIIERFDGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRIATSRTYRHFGLEQIEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y232_RICCO
Sequence: MESEQRRKRKRIYKPDSTSNSFFSVRSLTACLSFFVFLLFISSDRSPIKTVSFRPVLNVPVSLLPTPLGLTRDSFDTKSLPLIVEDRVLLPDHVLLIVSNKVATSQNLDCVYSNLYNSHDVVLKPALSVNQYHRDKSIVRCQLPPNNYSAAVYLRWSWEAAEGVAAAAPASVVSWDRVVYEAMLDWNTVAVFVKGLNLRPHKESDSSKFRCHFGLSKFDKDEGIVFTTEAITAAQEVIRCLLPRSIRNNPVKAQGIRVTVSRINAGEDGVDAPLPSVAKVYGAKSYEKRSNRGKYELCACTMLWNQASFLHEWITYHAWLGVQRWFIYDNNSDDGIQEVVDELNLQNYNVTRHSWPWIKAQEAGFSHCALRARSECKWLGFFDVDEFFYLPRHRGQDMLGENSLRTLVANYSDSSTYAEIRTICHSFGPSGLTSAPSQGVTVGYTCRLQAPERHKSIVRPELLDTTLLNVVHHFKLKEGYRYLNVPESTAVVNHYKYQVWDTFKAKFFRRVSTYVANWQEDQNQGSKDRAPGLGTVAIEPPDWRLRFCEVWDTGLKDFVLANFADTASGYLPWERSPF
What are the official names of this protein?
Glycosyltransferase family 92 protein RCOM_0530710.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 92 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TFE_CALMQ
Sequence: MQPYIELVRRYVYRRILIEFGDDELGKLAVAIFNTLLSRGEAMTDDKLTSIVGYNAIDVRRILQALYNMRLASVVEEFNEAAGRIEQSWSIKDEDIRRFLINLIGGVLDKVGVLMQQLTNTPIYICPKCFKRYSEDDALMYDYKCPLDRTPLEYINPADYLTVLGAVEARLKKMMESVSKGSV
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.