PharMolix/UniProtQA huggingface dataset:
Protein: PSD_BURL3
Sequence: MNYPHPIIAREGWPFIAIAAVIALLIHAVGGFGFAWPFWLLLVFVVQFFRDPQRPIPAQPNAVLCPADGRIVAVETAQDPYANREALKISVFMNVFNVHSQRSPVDGAISKVEYFPGAFLNAAIDKASTENERNAVVIQTASGKTVTAVQIAGLVARRILCYVRAGEPLSRGQRYGFIRFGSRVDVYLPLGSRAKVSIGEKVYASSTILAELEQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IORA_PYRAB
Sequence: MVKVTDIVLWDKPGERVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAAVASRAGVYMEYSTNEKVAFETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGVNGGLVVVVADDPSMWSSQNEQDTRAIAKFANIPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRGDVVLGELPQEIKEGKRKFGDFKKNPERYVDIPAFQRPKHKWLLETIEKFREEFNNSPFNWIEGPEDAKVGIIAPGLSYAYVKEALAWLGVDNVKVLKLGTPFPVPYGLLEKFFQGLERVLIVEELEPVVEEQVKVWAFDKGINVEIHGKDLVPRVYEMTTRRAVEAIAKFLGLETPINFEEIDEKYKKVQEIVPPRPPSLCPACPHRNTFFALRKAATPRAIYPSDIGCYTLGVLPPLKTVDTTIAMGGSIGVAHGLSIALNGSIAEEQRKTGKGKKIIAATIGDSTFFHTGLPALANAIYNRSNVLIVVLDNLVTAMTGDQPNPGTGETPHGPGKRILIEEVAKAMGADFVAVVDPYDIKETYETFKKALEVEGVSVVVARRACALYRIGQLRRAGKQWPIYQVNEDKCTGCKICINAYGCPAIYWDPEKKKAKVDPLMCWGCGGCAQVCPFDAFEKVREGEL
What is the function of this protein?
Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
What are the official names of this protein?
Indolepyruvate oxidoreductase subunit IorA, IOR, Indolepyruvate ferredoxin oxidoreductase subunit alpha.
Protein: HPRT_DICDI
Sequence: MSREVIFTEKEIKERVSELGRQITQDYKDSKNLVLVGILKGSFVFMSDLVRSIHLPNTNVSLEFMSISSYGAETSSSGVIRIMMDLRTSIEGKDVLIIEDIVDSGLTLKHLMELLNHRNPNSLHTAVLLRKKEGLKVEVPVKYMGFDIPMVFIIGYGLDFAENYRELPYLGELKEECYKK
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_HELP2
Sequence: MYVVLEGVDGAGKSTQVGLLKNKFKNALFTKEPGGTKIGESLRRIALNENISELARAFLFLSDRAEHVESVIKPALKEKKLIISDRSLISGMAYSEFSSLELNLLATQSILPTKIVLLLIDKEGLKQRLSLKSLDKIENQGIEKLLTIQRNLKTHAYALREKFGCKVLELNAKESVKNLHEKIAAFIKCVV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RL24_DEIGD
Sequence: MPRPSAGSHHNDKLHVKKGDTVIVLRGKHKGQTGKVLLALPRDAKVVVEGVNLVTKHVKPSAANPQGGIEQREAALHASKVALVDPETGKPTRVRKAIVDGKKVRVAVKSGKVID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: IAA17_ORYSJ
Sequence: MSPPLELDYIGLSPPVPAAADAAADNDLKGTELRLGLPGSHSPDRSPPAATLDLLPAAKGAKRGFSDEARPLPASAAAAAAAGKGKKAAAGEEDEDAEEEDKKVAAAPQAPAAKAQVVGWPPIRSYRKNTMATNQLKSSKEDAEAKQGQGFLYVKVSMDGAPYLRKVDLKTYKNYKDLSTALEKMFIGFTTGKDGLSESRKDGEYVLTYEDKDGDWMLVGDVPWEMFANSCRRLRIMKGSDAIGLAPRAVDKSKNRN
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
What are the official names of this protein?
Auxin-responsive protein IAA17, Indoleacetic acid-induced protein 17.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL15_DESRM
Sequence: MNLSELRPAPGARKKPTRKGQGIGSGLGKTAGKGHKGQNARSGGGVRPGFEGGQMPLQRRFPKRGFTNIFKKQITAINLDELNVFEAGTEVTPELLLEAGLIKKVGDGVKILGDGILEKALTVKVHAFSKSAVEKITAAGGKAEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LPXK_SHEB8
Sequence: MQALVNKIWYQGHPLRWLLLPLSWLFAVITYVRRALFRLGIKSQTVMPVPVIVVGNITVGGSGKTPTVIYLIELLRQHGFTPGVVSRGYGVDIQGVKTVNLGASAAEVGDEPAMIVARTQVPMVVGAKRVDAANALIAEFGVDVIICDDGLQHYALGRDIELVVIDGQRGLGNGLLLPAGPLREGAWRLDAVDFIVNNGGPAAKGQFEMQLAPTEVKPVKCDLTSGEYSFDKSQPLVAMAGIGNPARFFESLRAQGYQLALCQGFDDHQPYDKTQLRDLAQDLPLLMTEKDAVKCRDFAQENWWYLAVNAKLSPQFDEQLLARLREVAAAKQGNFHGIR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: DOCK9_MOUSE
Sequence: MGCTTSVILFKGIRTVFERNCAYMCKQPGESNALEYTAYNWSKEDSELSIAFCLAKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYLRSTVPANAEEEAQSLFVTECIKTYNSDWHLVTYKYEDYSGEFRQLPNKVPKLDKLPVHVYEVDEEADKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVIQNNRVRRFAFELKMQDKSSYLLAADSEAEMEEWVTVLNKILQLNFEAAMQEKRNGDPHEDDEQSKLEGSGSGLDSYLPELAKSTREAEIKLKSESRVKLFYLDPDTQKLDFSSAEPEVKPFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLAPTSPALMNGGQSPPAFQDALHTAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMRSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDTSGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDSVSCDFPNYLNSSYIPMRQFETCSKSPITFEVEEFVPCIPKHTQPYTVYSNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSALAAVLHHQQNPEFYDEIKIELPAQLHERHHLLFTFFHVSCDNSTKGSTKKKDAVETQVGFSWLPLLKDGRVLTSEQHIPVSANLPSGYLGYQELGMGRHYGPEVKWVEGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQASGSELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKFAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENNKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRVIAISMLKNLLIKHSFDDRYNSRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNPGSIVKDEALAVPAGNPLMTPQKGNTLDHSLHKDLLGAISGIASPYTASTPNINSVRNADSRGSLISTDSGNSLPDRNPEKSNSLDKQQQSGMLGNSVVRCDKLDQSEIKSLLMCFLYVLKSMSDDALFTYWNKASTAELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSVTFNHSYGHSEADVVHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSEMALKNVFTALRSLIYKFPSAFYEGRADMCASLCYEVLKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRIIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKGMFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKFAYIQVTHVTPFFDEKELQERRTEFERCHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSDIMREQMG
What is the function of this protein?
Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP (PubMed:25851601).  Overexpression induces filopodia formation (By similarity).
What are the official names of this protein?
Dedicator of cytokinesis protein 9, Cdc42 guanine nucleotide exchange factor zizimin-1, Zizimin-1.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Endomembrane system. Note=Associated with membranes.
Protein: VG18_BPMD2
Sequence: MRIQSTVNGGFAEVSDEYAQRLIAAGGWKRPRKPRTTKPKPAPKQEPATEE
What are the official names of this protein?
Gene 18 protein, Gp18.
Protein: ZN346_HUMAN
Sequence: MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED
What is the function of this protein?
Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (PubMed:24521053).  May bind to specific miRNA hairpins (PubMed:28431233).
What are the official names of this protein?
Zinc finger protein 346, Just another zinc finger protein.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5.
Protein: MGSA_BRUSI
Sequence: MTQRLRIALIAHDQKKDDMVAFARAHEQALSRYDIVATGTTGGLIQDACPSLNIHQVKSGPLGGDQQIGAMIAEGTVEVLIFFIDPLSPLPHDVDVKALTRLGSVYDIPMALNRATAEKLVRALD
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: G3P_ZYMMO
Sequence: MAVKVAINGFGRIGRLAARAILSRPDSGLELVTINDLGSVEGNAFLFKRDSAHGTYPGTVTTEGNDMVIDGKKIVVTAERDPANLPHKKLGVDIVMECTGIFTNTEKASAHLTAGAKKVLISAPAKGDVDRTVVYGVNHKDLTADDKIVSNASCTTNCLAPVLHVLQQKIGIVRGLMTTVHSFTNDQRILDQIHSDLRRARTASASMIPTSTGAARAVALVIPELKGKLDGISIRVPTPDVSLVDFTFVPQRDTTAEEINSVLKAAADTGDMTGVLGYTDEPLVSRDFYSDPHSSTVDSRETAVLEGKLARVVAWYDNEWGFSNRMVDTAAQMAKTL
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDIB_SALSV
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDFFEKAVAFAKRVNENTDCVVTVTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RL16_EHRCJ
Sequence: MFIPKKTKYKKDFKGRISGNAKGGYTLSFGSYGLKALEPCRLTSKQIESARRSISRTLKRVGKVWIRAFCHTSVSKKPMDVRMGKGKGSVEMWVCKVKPGKILFEISGVSLNLAREALNKAQAKLPMKCKFVSDEL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y545_RICPR
Sequence: MLKIISGKYKNQIIPTAQNIKYRPSTGKLKEAIFSILTSGEFIGNKLFNENTQILDLFAGSGSLAFESLSRGAGFATLIDIDTYSLKIAAGFAKSLNIENNVHFININALNLQKTTRYLSKQTDRNEFITTAESYIGISKHKSTNITYKLPLKEQFCNMSNKVFDLVFIDPPYNKDIVPKVMKLLIKNNWLKNGTIIVIEMSKTDDYDLDKNIEIIRAKLYGQSKLLVLRYSSHLR
What are the official names of this protein?
Uncharacterized methylase RP545.
Protein: FOS_PHOCM
Sequence: MMFSGFNAEYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCADLSVSSANFIPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGVPTPPTGAYSRAGMVKTVSGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDHLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEDMSVASLDLTGGLPEATTPESEEAFSLPLLNDPEPKTSLEPVKSISNMELKAEPFDDFLFPASSRPSGSETTARSVPDMDLSGSFYAADWEPLHSSSLGMGPMATELEPLCTPVVTCTPSCTTYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL
What is the function of this protein?
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor.  On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling.  Has a critical function in regulating the development of cells destined to form and maintain the skeleton.  It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity).  In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A.  This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Protein c-Fos, Cellular oncogene fos, Transcription factor AP-1 subunit c-Fos.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Cytoplasm, cytosol. Note=In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and only later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30 (By similarity).
Protein: PDXH_CUPMC
Sequence: MTQLADLRRNYMLSALSETDVAPDPIRQFQSWFDEAMQAKLPEPNAMTLATVGADGQPSARIVLLKGMDADGFTFFTNYESRKGVDLLANPRAALLFHWVQLERQIRVEGIVEKVEDAESDAYYASRPLGSRLGAWASEQSREVAGRDVIEAREADFRNKFGENPPRPPHWGGYRLKPTWIEFWQGRPSRLHDRIAYRQNADGNWQIVRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: MURA_MYCTO
Sequence: MAERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVARITAPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGAHCNIEHGCVVARAETLRGAEIQLEFPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLHPTEHRVIGDRIVAATWGIAAAMTRGDISVAGVDPAHLQLVLHKLHDAGATVTQTDASFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLVSLGAEIERVCC
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_MYCLB
Sequence: MLVRLVFAGTPESALPALCRLIDSPRHDVIAVLTRPDAASGRRGKPEPSPVAREALDRGIPLLRPARPNSPVFVSELSEWAPECCVVVAYGALLGSPLLAVPPRGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGPVYGVVTETIQPTDTAGDLLERLAVSGATLLSSTLDGIADAILTPRQQPVDGVSFAPKITVEQARVCWDLPAPVVERRIRAVTPNPGAWTLVGKLRVKLGPVRFDSGAVEVPRLLKPLLPGGIHVDHKSVWIGTGSDPVRLSKVQPQGKKFMNAVDWAHGARLDPAARAS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: HSLV_TREDE
Sequence: MSQKIRSTTVIAVRKDGKIVMAGDGQVTMGETVMKGNARKVRKIYDGKIITGFAGATADAFTLLEKFEIRVKEFSGDLTRAAVELAKDWRTDKMLKNLQALLLVADSKTTLLISGNGDVIEPEEDVLAIGSGGNYAYASALALMQNTNLSAREIAEKSLQIAGKICIYTNGKIITEEI
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_VIBVU
Sequence: MSITNEQILDAIAEMSVTQVVELISAMEEKFGVTAAAAVVAGGAAAGAAVEEQTEFNVILASAGANKVAVIKAVRGATGLGLKEAKALVDGAPAALKEGVEKAEAEALKKELEEAGATVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DNAA_STRPS
Sequence: MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFLPRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYSPKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLGKTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLIDDIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQTITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVKKIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVLARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKKKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_STRPM
Sequence: MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALMREYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_STRP3
Sequence: MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_DICCI
Sequence: MKSLFEQFEIDLYCIIITRFFDVSITTITVYLGLLMVIVIGMYKVSLYKATLIGNNNWQHIGEMIYEFVVDLILEQVGKPGILFFPFIMSLFLFVLTLNVMGLIPLSFTVTGQLLVTFTLAITIMIGITIWGFRIHGIKFLNIFVPSGIEPWLLPLLVFIEIMSYVLRPISLAVRLFANMLAGHLLIHIIGVAAIYLMQFYFIGILPWICVIAFMFLELGIAFLQAYVFVLLTLIYIANIINLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DPO4_STRP3
Sequence: MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKDPRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRIFKRYTDVVEPMSIDEAYLDVTDNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKFLAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLAVPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEISKNAKRVVALLQDHKKLGKTIVLKVRYADFITLTKRVTLPELTRDAAQIEQVAESIFDTLPEHTVGIRLLGVTMTNLEDKMADIALDLS
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_CLOPE
Sequence: MGKKYIESSKLIDKNALYTPAEALELAVKTAKAKFDETIELHVRLGVDPRHADQQVRGAVVLPHGTGKDVKVLVFAKGEKAKEAEAAGADFVGADELVQKIQGENWFDYDVVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVANAIKEIKAGKVEYRVDKTAIVHCPIGKKSFGTEKLVENFKALMDALVKAKPAAAKGQYLKSVSVSATMGPGAKVNPAKVLD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.