PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_PECAS
Sequence: MKESEGIDLSTHTPMMQQYFRLKAEHPEILLFYRMGDFYELFFDDAKRASQLLDISLTKRGASAGEPIPMAGVPHHAVENYLARLVQMGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQEKQDNLLAAIWQDGRGFGYATLDISSGRFRVSEPADRETMAAELQRTNPAELLYPESFESMELIDNRHGLRRRPMWEFEPDTARQQLNLQFGTRDLTGFGVEQAKLALRAAGCLLQYAKDTQRTSLPHIRGITMERQQDGIIMDAATRRNLELTQNLSGGVENTLAAVLDCTVTAMGSRMLKRWIHMPSRDIDALKQRQQAISALQEITPDLQPYLRQVGDLERILARLALRTARPRDLARMRHAFQQFPDIREQLAPLDTDSVRRLVSLIGQFDELRDLLERAVVEAPPVLVRDGGVIAPGYHTELDEWRALADGASDYLDRLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKALYDELFDLLLPHLAELQQSAAALAELDVLTNLAERADTLNYVCPTLSDKPGIKIAGGRHPVVEQVLREPFISNPLSLSPQRRMLIITGPNMGGKSTYMRQAALIVLMAHIGCFVPADQAVIGPVDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAESLANRIKAMTLFATHYFELTTLPEKMEGVVNVHLDAREHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLKELETLSNNASSSHIDGAQLALLNTDEPSPAIEALEAIDPDALTPRQALDWLYQLKKML
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MNME_STAA9
Sequence: MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_SHEDO
Sequence: MSEKKINLLDLDRKGLRALFTEMGEKPFRADQLMKWIYHFGVSDFEEMTNINKVLRSKLAERCVIVAPEIASFQKSADGTIKFAINVGQGQEVETVYIPEDDRATLCVSSQVGCALECTFCSTGQQGFNRNLTVSEIVGQIWRVAQFLGFVKTTGERPITNVVMMGMGEPLLNLKNVIPAMDIMLDDFGFSLSKRRVTLSTSGVVPALDILGDSIDVALAVSIHAPNDELRDILVPVNKKYPLAEFLGGIRRYIAKSNANRGRVTVEYVMLDHINDSTEQAHELAKLMKDTPCKVNLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGFTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKRMQENQISVTMD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_RHOPT
Sequence: MTETDGQKDNNQDTAQAAADPVVSKPYIMPDDPEEGSNEALVREAADARDKMLRTLAEMENLRKRTQKEVADARTYGVTSFARDVLDIADNLQRALDAVPAEARANAEPGLKALIEGVELTERSLLNALEKNGVKKFDPKGQKFDPNFQQAMYEVPDPSVPAGTVVQVVQAGFTIGDRVLRPALVGVAKGGAKAAPSDGGSETGNLN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYDC3_PETCR
Sequence: MGSIDNLTAQKLTSSQFPMNTLEPEEFRRQGHLMIDFLADYYRKVENYPVRSQVSPGYLREILPESAPYNPESLETILQDVQTKIIPGITHWQSPNFFAYFPSSGSTAGFLGEMLSTGFNVVGFNWMVSPAATELENVVTDWFGKMLQLPKSFLFSGGGGGVLQGTTCEAILCTLVAARDKNLRQHGMDNIGKLVVYCSDQTHSALQKAAKIAGIDPKNFRAIETTKSSNFKLCPKRLESAILYDLQNGLIPLYLCATVGTTSSTTVDPLPALTEVAKKYDLWVHVDAAYAGSACICPEFRQYLDGVENADSFSLNAHKWFLTTLDCCCLWVRDPSALIKSLSTYPEFLKNNASETNKVVDYKDWQIMLSRRFRALKLWFVLRSYGVGQLREFIRGHVGMAKYFEGLVGLDKRFEVVAPRLFSMVCFRIKPSAMIGKNDENEVNEINRKLLESVNDSGRIYVSHTVLGGIYVIRFAIGGTLTDINHVSAAWKVLQDHADALLDDAFLPKKIVNILS
What are the official names of this protein?
Tyrosine decarboxylase 3.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: GSA_COREF
Sequence: MVDMSASPSGTSANVSRSIEWFEKAKMFTPGGVNSPVRAFGSVGGQARFIDRAHGSTLIDVDGNEYVDLVCSWGPMLMGHAHPAVLEAVQKTIVDGLSFGAPTIGEVELAQDIINRTSVEEVRLVNSGTEATMSAVRLARGYTQRPKILKFDGCYHGHVDSLLASAGSGVATFALPDSPGITGAQTRDTIVVPYNDIEAVRAAFAEFPGQIACIISEAAAGNMGTVAPQDHFNEHLLAIAHADGALLILDEVMTGFRTSYRGWFGVDKVRADLVTFGKVVSGGLPAAAFGGRAEIMNMLAPQGPVYQAGTLSGNPVAVAAGRASLSAATEEVYRTIDANADRLHGLISDALTREGVAHHIQRASNMLSIRFAEGEGHNFTDMKNADTFRFAPFFHALLDHGVYAPPSVFETWFVSSALTDDDFQKIDDALVPAARAAAAATA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_ECODH
Sequence: MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_TREPA
Sequence: MSLSGHTHTKEEVQAEVEAGEVQCPALCHQPVLVQECLTLLEPAIVGISRGADSTRDGAGAFFIDGTLGDGGHTQAFLHAYPALRALGVEIDPSMLARARARLTPFGKRLRYVLGWSDVFFASAYASAPASPATGRTAAGAAGVPGAYPAPQAVLLDLGISFFHYRGAMRGFSFAEEHMLDMRLDPQASQTAADLLNRLPQARLAQLFFEGGEERYARRIAQAVCAQRRQAPFCSARAFAEVVARVVPPMRTARFGKRRGVLGVLPKLHPATKAFQALRIAVNRELERLPRLLTAAFTALAPGGRLAVISFHSREDRIVKVHFRHWAKRCSCPARVPICSCGGVARASLITKKPLVPSCVERAANAASRSATLRVIEKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPL1_SELML
Sequence: MSEHRIPVAADKKISPPISAGEQKGCKGLKRTDLMLRFAAFVCCTVTMVVLITDKQTSAIQVPGFNNLTITKTVSFDLAKAFVYLVSAAGIGAGYTLLVLVLSIISAERSKAIAWFIFVFDQLITYVLLAAAAASTEVAYMGAHAPPEASWLKVCSLFGRFCHQLGASLVTSLISTVLFAFSAAISAYYLFSNTNVRPAYSKG
What are the official names of this protein?
CASP-like protein 2U6, SmCASPL2U6.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMH_DESTE
Sequence: MHITLLCVGKLKEDFLLLAQKEYLKRLSPYARIELVEVREESLPASGRAGALEAVLKKEGTRLLERIPDNCVTIALDRKGMMLSSKEFAGYLAELGLRGQNKLCFIIGGSAGLAGDVLARASLRLSFSKFTFPHQLMRIILLEQIYRAFKIIRGEKYHL
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_ECOSM
Sequence: MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNALLWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLETREMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: ISPG_YERPN
Sequence: MHNGSPIIRRKSTRIYVGKVPIGDGAPIAVQSMTNTKTTDVDATVAQIKALERVGVDIVRVSIPTMDAAEAFKLIKQQSTVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNESRIREVVACARDYNIPIRIGINGGSLEKDIQEKYGEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVNSYRLLAKQINNPLHLGITEAGGARSGSVKSAIGLGLLLSEGIGDTLRISLAADPVEEVKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDLITPMDVSIIGCVVNGPGEALVSTIGVTGARNHSGFYEDGVRQKERFDNKAMIDQLEAKIRAKASILDANNRIVINQLDDNK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PPIA_ECO57
Sequence: MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVLP
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PUR5_THEGJ
Sequence: MLTYAQAGVDDEKTVRALKNIIGLARETFKFRRGKPGEPAENLGHYSALLDFGNFYLAMTTDGVGTKVLVAEAVGKFNTIGIDMIAMNVNDLLCVGAEPIALVDYLAVREPDEKIFAEIAKGLYAGAEKAGIAIVGGETAVMPDLINGFDLAGTAIGIVEKGKVITGEEMRPDDAVIGISSSGIHSNGLTLARKLLIPKYGLDYEYEGRKLWEWLLEPTRIYVRAVLELLERVEVHGLAHITGGGLINLKRLTNYGFSLEMPPIEGIFKLIHENGVPLEEMFRVFNMGVGFVAIVPPEEKEEALGILNKYYESFELGRVTKEPGIRVENYGIKL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_CITK8
Sequence: MAKLTKRMRVIREKVDATKQYDINEAISLLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAEQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQSGLTATVAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: FBIB_MYCBP
Sequence: MTGPEHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLRDGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDRTLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLGVTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTEVAVADEIAAAADLVKGKLTATPVAVVRGFGVSDDGSTARQLLRPGANDLFWLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQILYDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVRGLGSCWIGSTIFAADLVRDELDLPVDWEPLGAIAIGYADEPSGLRDPVPAADLLILK
What is the function of this protein?
Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
What are the official names of this protein?
Bifunctional F420 biosynthesis protein FbiB.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the CofE family.
Protein: FUS_PI2HT
Sequence: MHHLHPMIVCIFVMYTGIVGSDAIAGDQLLNIGVIQSKIRSLMYYTDGGASFIVVKLLPNLPPSNGTCNITSLDAYNVTLFKLLTPLIENLSKISTVTDTKTRQKRFAGVVVGLAALGVATAAQITAAVAIVKANANAAAINNLASSIQSTNKAVSDVIDASRTIATAVQAIQDRINGAIVNGITSASCRAHDALIGSILNLYLTELTTIFHNQITNPALTPLSIQALRILLGSTLPIVIESKLNTNFNTAELLSSGLLTGQIISISPMYMQMLIQINVPTFIMQPGAKVIDLIAISANHKLQEVVVQVPNRILEYANELQNYPANDCVVTPNSVFCRYNEGSPIPESQYQCLRGNLNSCTFTPIIGNFLKRFAFANGVLYANCKSLLCRCADPPHVVSQDDTQGISIIDIKRCSEMMLDTFSFRITSTFNATYVTDFSMINANIVHLSPLDLSNQINSINKSLKSAEDWIADSNFFANQARTAKTLYSLSAIALILSVITLVVVGLLIAYIIKLVSQIHQFRSLAATTMFHRENPAFFSKNNHGNIYGIS
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with HN at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: RL17_THEVB
Sequence: MRHQRRVPQLGRPADQRKALLRALTTELIRHGRITTTKARAKAVRAEAERMITLAKDGSLAARRRALGYLYDKQLVHSLFAQAPERYGDRQGGYTRIIRSVRRRGDNAELAVIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: AKNOX_STRGJ
Sequence: MFVLNEFTRRGFLGTAAAVGGTTVVTTALGGAPAAQAAVPEAADGGACGARTALVKVDRVDRRYQDLVTRGFNGRFRGRPDVVYVVHTADQVVDAVNQAMAAGQRIAVRSGGHCFEGFVDDPAVRAVIDMSQMRQVFYDSGKRAFAVEPGATLGETYRALYLDWGVTIPAGVCPQVGVGGHVLGGGYGPLSRRDGVVADHLYAVEVVVVDASGRARKVVATSAADDPNRELWWAHTGGGGGNFGIVTRYWFRTPGATGTDPSQLLPKAPTSTLRHIVTWDWSALTEEAFTRIIDNHGAWHQSNSAAGTPYASMHSVFYLNSRAAGQILLDIQIDGGLDGAEALLNDFVAAVNEGTGVEPAVQRSTEPWLRATLANKFDTGGFDRTKSKGAYLRKPWTAAQAATLYRHLSADSQVWGEVSLYSYGGKVNSVPETATATAQRDSIIKVWMSATWMDPAHDDANLAWIREIYREIFATTGGVPVPDDRTEGTFINYPDVDLVDERWNTSGVPWYTLYYKGNYPRLQKVKARWDPRDVFRHALSVRPPG
What is the function of this protein?
Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group.  In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA).  In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 and the generation of the L-aculose terminal sugar moiety of aclacinomycin Y (AclY).  It can also use aclacinomycin analogs, epsilon-pyrromycinone glycosides, rhodirubins (A, B, C and E) and all triglycosides containing L-cinerulose, L-rhodinose or 2-deoxy-L-fucose as terminal sugar.
What are the official names of this protein?
Aclacinomycin-N/aclacinomycin-A oxidase, AknOx, Aclacinomycin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: HBA_CARCR
Sequence: VLSSGDKANVKSVWSKVQGHLEDYGAETLDRMFTVFPQTKTYFSHFDVHHGSTQIRSHGKKVMLALGDAVNHIDDIATALSALSDKHAHILRVDPVNFKLLSHCLLVVVARHHPTLFTPDVHVSLDKFMGTVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: VC14_VACCC
Sequence: MSILGVSIECKKSSTLLTFLTVRKMTRVFNKFPDMAYYRGDCLKAVYVTMTYKNTKTGETDYTYLSNGGCLHTIVMGSMVDY
What are the official names of this protein?
Protein C14.
Protein: RR18_CUSOB
Sequence: MDKITGPFRKSKKSFRKPLPPIQSGDRIDYQNIDVLRRFISQQGKILSRRVNRLTLKQQRLLNLAIKQARILSFLPFTNTESLEKMKARIREARLKAEEVRLKNKEARLKKAKDARLKAKEARNQKKTTLRKIFINPKTSKLNTETSQT
What are the official names of this protein?
Plastid 30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid.
Protein: CCNB1_MEDSV
Sequence: MKFSEEKNVSNNPTNFEGGLDSRKVGQNRRALGVINQNLVVEGRPYPCVVNKRALSERNDVCEKKQADPVHRPITRRFAAKIASTKTSNAEGTTKRSNLAKSSSNGFGDFIFVDDEHKPVEDQPVPMALEQTEPMHSESDQMEEVEMEDIMEEPVMDIDTPDANDPLAVAEYIEDLYSYYRKVESTSCVSPNYMAQQFDINERMRAILVDWLIEVHDKFDLMHETLFLTVNLIDRFLEKQSVVRKKLQLVGLVAMLLACKYEEVSVPVVGDLILISDRAYTRKEVLEMEKVMVNALKFNISVPTAYVFMRRFLKAAQADRKLELLAFFLIELSLVEYAMLKFSPSQLAAAAVYTAQCTMYGVKQWSKTCEWHTNYSEDQLLECSSLMVDFHKKAGTGKLTGAHRKYCTSKFSYTAKCEPASFLLENEL
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-1, B-like cyclin, CycMs1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: UTP25_ASPFC
Sequence: MDHETQMDDVLSDSDDDEDQQTARPYNELIQLLQVNTEPKGPARKRRKVEYNGGEKRDFVPAANGEEVDAALQGDDDLQEQEPSDEEEEDHPEEADGNHGSDDEEDANDPFETHFSAIDENKLALKIKSAEEKKWKNAKKEISSGLKLVRAIPDVGEGDVSLLPAMKHFSSVKLKKKLCGPATERIPEISGDAQHIAPYIFNYQDVLYGARTTSNSSAMRDILAVHAVNHILKTRDRVLKNNSRIAKEQDADLDLRDQGFTRPKVLYLLPTRQACVRAVESITRFFQPEQQENKKRFLDSFSAADDKSWENKPEDFRELFGGNDDDMFRLGLKFTRKTMKYFSQFYNSDIILASPLGLRTIMDQADVKKRDHDFLSSVELVIVDHADALLMQNWDHVGYILDRLNLQPKEAHGCDFSRVRTWYLDNHARFVRQMIVSASFITPEINSLFSTHMQNFAGKVKVTPVYVGAISEVPLPVSVKQTFSRFDSLTPTKDPDARFKHFTTTVLSSLVRNITSSRDKSSAGGTLIFIPSYLDFVRVRNYFATSSQTTNVSFGAISEYSEVREMTRARTHFMNGRHAVLLYTERLHHFRRYQLRGVKRIVMYGVPENPLFWGEIVGFLGLDPAGVVDAAEGGVRALFSKWDALKLERIVGTKRVGNMLREKGGDTFTFV
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HSCB_PSEA6
Sequence: MNYFALFNLTPSFDVDKAALAATYQQLQKLTHPDRFATASERDKLIALQKNAQVNDGYQVLKTPLSRAEHMLELRGVELQHEQKTMQDGAFLMQQMEWREQLDDAQHASDPLTALESLDDEVAADIKRLLSELGGFLEQSDDAANENAANLVRKLKFLFKLRHEIEIKEDALSDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: T2R31_PANTR
Sequence: MTTFIPIIFSSLVVVIFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVLNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVILVMLLGPLLFLACQLFMINMKEIVRTKEYEGNMTWKIKLRSAVYLSDATVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKVLQTVISFLLLCAIYFLSIMISVWSFGSLKNKPVFMFCKAMRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYWVKGEKPSSP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 31, T2R31, Taste receptor type 2 member 44, T2R44.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COBL_MYCTO
Sequence: MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLHSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
What is the function of this protein?
Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X.
What are the official names of this protein?
Precorrin-6Y C(5,15)-methyltransferase [decarboxylating], Precorrin-6 methyltransferase, Precorrin-6Y methylase.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: GLO2_ROSDO
Sequence: MPIEILTIPCLNDNYAFLVHDTATGQTALIDVPEAAPILKVLAERTWQLSEVWITHHHADHVQGLGDILSAHPAQVRGAARDAHRLPALDVELRDGESFDFAGHKVDVMDVSGHTVGHIAYYCADAKAVFTADSLMALGCGRLFEGTADQMWDSLSKLAALPSETQVYSGHEYTAANARFALTIDPHNPDLISRSEGITAARAAAKPTVPSTLATEAATNPFLRAADPAIRAHLNMQHASDSEVFAEIRARKDAF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: RDGC_VIBCH
Sequence: MWFKNCMVYRVNREVNFNADQLEKQLAEFRFTPCGSQDKQKFGWVSALGKHGDMMTHVSENRILVCAKREEKMLPASVIKDSLNAKVEEMEAEEGRPLKKKEKDALKEDIVIDLLPRAFSKSQLTFVLIMPTEGLILVDAGSYKKAEDVLSLLRKTMGSLPVVPAIPEIAVETTLTQWVKDGNLPQGFSLMEEAELKSLLDDGATIRCKKQELSSDEILSHIQANKVVTKLAINWQDRIRFVLAEDCSIKRLAYSDELKEQNDDIPHEDRAARLDADFSLLCGEMSVFLPDLFNALGGLPHPEA
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.