PharMolix/UniProtQA huggingface dataset:
Protein: RR15_MORIN
Sequence: MIKKSFISVISHEEKEKNRGSVTFQILSLTNRIRKLSSHLELHRKDYLSQRGLRKILGKRQRMLSYLSKNNRIRYKELINQLDIRESKTR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MRAZ_RICBR
Sequence: MNIFLSKFINNNIDKKGRVSVPANYRAVLGKEAFNGIIAYPSIRNNCIEACGISHIEKLRQMIESLDPYSEERDAFETIIFGEAVQLSFDGEGRVILPASLMQHAGIEDQVCFVGKGVIFEIWQPQNFKDYLASAQKLAHEKRLTLRNTN
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KLF11_MOUSE
Sequence: MHSPGSTGPGDGRAADIMDICESILERKRHDSERSTCSVLEQTDIEAVEALVCMSSWGQRSQMRPLTPVSDSGDVTTAVLMDTAAPDLPKDFHSFSTLCITPPQSPELTEPSTGTPVPSQVVNSKGCMVTALPPSPAGGPRTLSKREPLEPASGSSCRAVMTSVIRHTGESPAPTRFPTGPTQEQRASDSGEGQERLLDHLEALQDTRLANGLLVTNLVSCQPCLHKSGGSFPTDKGQQTGWPAAVQTCLPKNPESDLSRKITPLISVPVSSPPVLCQMIPVAGQNGLFSAFLKPPTQLPAGTIKPILPQAASMSQPVFMGPPVPQGTVMLVLPQNTFPQPAACPSSVMAIGNTKLLPLAPAPVFLASSQNCAPQVDFSRRRNYVCNFPGCRKTYFKSSHLKAHLRTHTGEKPFTCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRITLAESPGSILEPLPASG
What is the function of this protein?
Transcription factor.  Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding sites inhibiting cell growth (By similarity).  Represses transcription of SMAD7 which enhances TGF-beta signaling.  Induces apoptosis.
What are the official names of this protein?
Krueppel-like factor 11, TGFB-inducible early growth response protein 2b, Transforming growth factor-beta-inducible early growth response protein 3, TGFB-inducible early growth response protein 3, TIEG-3.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDEAS_HUMAN
Sequence: MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNGREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRERSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSEKKKKTETFSKTQNQENTFPCKKCGR
What are the official names of this protein?
Mitotic deacetylase-associated SANT domain protein, ELM2 and SANT domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAHD1_HUMAN
Sequence: MARQPEEEETAVARARRPPLWLLCLVACWLLGAGAEADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRSHHPTLHHSHHLQAAVTVHTVDAEC
What is the function of this protein?
May regulate voltage-dependent calcium channels.
What are the official names of this protein?
VWFA and cache domain-containing protein 1, Cache domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel subunit alpha-2/delta family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL22_STRZT
Sequence: MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTPNKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTAHITVAVAEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GRXS8_ARATH
Sequence: MEKIQKMISEKSVVIFSNNSCCMSHTIKTLFLDLGVNPTIYELDEINRGKEIEYALAQLGCSPTVPVVFIGGQLVGGANQVMSLHLNRSLIPMLKRFGALWL
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides.
What are the official names of this protein?
Monothiol glutaredoxin-S8, AtGrxS8, Protein ROXY 15.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TMCAL_STRA1
Sequence: MTVTGIVAEFNPFHNGHKYLLEQAQGIKVIAMSGNFMQRGEPAIVDKWTRSQMALENGADLVIELPFLVSVQSADYFASGAVSILARLGVDNLCFGTEEMLDYARIGDIYVNKKEEMEAFLKKQSDSLSYPQKMQAMWQEFAGITFSGQTPNHILGLAYTKAASQNGIRLNPIQRQGAGYHSSEKTEIFASATSLRKHQSDRFFVEKGMPNSDLFLNSPQVVWQDYFSLLKYQIMTHSDLTQIYQVNEEIANRIKSQIRYVETVDELVDKVATKRYTKARIRRLLTYILINAVESPIPNAIHVLGFTQKGQQHLKSVKKSVDIVTRIGSQTWDSLTQRADSVYQMGNANIAEQTWGRIPFYQPVSQSDL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK2_STRAW
Sequence: MTQTRARTVFLLAHTGRPAAIRSAELVVQGLLRSGLGVRVLEAEAADLPLPDEVELVKEATPQCLDGCELLIVLGGDGTLLRGAEFARASGVPMLGVNLGRVGFLAEAERDDLDKVVDRVVTKAYEVEERMTVDVVVHKNGDIVHTDWALNEAAVQKVSAERLLEVVLEIDGRPVTGFGCDGIVCATPTGSTAYAFSAGGPVVWPEVEALLMVPISAHALFAKPLVTSPNSVLAVEVQPDTPHGVLWCDGRRTVELPQGARVEVRRGAVPVRLARLHHASFTDRLVAKFALPVAGWRGAPH
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_ROSS1
Sequence: MYRSHTCGELRAEHIGQEVLLAGWVHRRRDHGPLIFIDLRDRYGITQIVFDSADSPVAHAVASDARVEYVLQVRGRVVQRPEEAYNPDIATGMIEVHATEATVLNPAKTPPLYINKEGGEEETLRLKYRYLDLRRERMQRNIMLRHRIVKFIRDFLDREGFVEIETPILIKSTPEGARDYLVPSRLHPGKFYALPQSPQQLKQLLMVAGFDRYFQIARCFRDEDQRADRQPEFTQLDMEMSFVDQGDVLDIIERLFTALCREIVPHKRLVTPFPRLTYAEAMERFGSDKPDLRYGLELVDVSDVVAASSFGVFRAALDTGGQVKGLRIPGAGSYSRKQIDEVVELAKQAGARGLLWAVVPGEGGEVRSSFGRQVSPDEMAAIIRRMEGAPGDLLLIVADPPKIVAQTLDRLRREFGARLNLADPNVLAWAWVIDFPLVEWNEEEQRWDAVHHPFTAPKDEDLHLMDTDPGRVRAKAYDLILNGYEAGGGSIRIHRRDVQQRLFDLLGIDRETAMRQFGHMLEAFEYGAPPHGGIAPGIDRICMILADEVTIREVMAFPKTQQAVDLMTNAPSPVDERQLRELHIALRLD
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_STRP7
Sequence: MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSIGGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIRLTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DNAA_BORBU
Sequence: MEKSKNIWSLILTEIKKELSEEEFYVWFENLCFLESIGDNIKISTPNLFHKNQIEKRFTKKIKEILIKNGYNNIVIVFTNQPPKTHSNKQETKNPALNETFSKFDKLKEKTTSKEAIQNIQDRIKMYIKKEEEEPTNFKNPFLKKRYTFENFIIGPNNKLAYNASLSISKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHHNLKILYVTAENFLNEFVESIKTHETKKFKKKYRYLDMLLIDDIHDLQKKEGIQEELFHTFNALYEDNKQLVFTCDRSPSELTNFTDRLKSRFTRGLNVDISKPNFELRAAIVEKKAEEDGINVPKNILNLVAQKVTTNVRDLEAAVTKLKAYIDLDNIEIDIEIVEKIIKEIIIYEKETTNEPNNKINIENIKKILLRELKITHKDIEGHSKKPEITKARHIYAYLLRNFTELSTVEIGKIIGGKTHSTVLYSINKIDRDRNNDKEINNLITELMNKIKKN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3C_CORMM
Sequence: MVGEPKIVSVWQFPFPIVTGRHLPYCPGNCAAHLNYEIAHQLLFSLSHQPRSRILVNRMIFSSPAWVPSPDQSAPDQVPIGDYVLSNHVLSKNDAPFVDAISGHVYTMAMLRTRVESLARGLAADLNWSPNTGSPEEKVVAIYSLNTVALSGPLLTIMYKIDYFILCWAVHRLNGICMPLHSTCTSAEITSHMITASCTTIFTCSGLMSTCLEAAKELQLPAEKIYTLALPSTYLDNANLEDSPRLKTLEQLADQGSQLPQLEPLRWSAGQGKSQVAFLCSTSGTSGRQKLAMLTHYGIITNLLQMSAFEGFANDTYGQTVAAAIPFSHSYGILIGHVGVLRGESHIVFPRFDMQRMLGSVASYRVNRLYLVPPILAVLGANSFLMEPFDLSSVTSVVTGAAALDRTVAGRLKSLQPSWEFLHAWGLTETCIVVTFTSKHDVWYGSSGSLLPGCQLRLVDAEGKDVENYDQSGEVYYKAPNMFVGYLGDHESTISSFDDDGWMRTGDMGAIQVSPNGVEHLFIRDRIKDMIKVKGMQVIPADVEAAMLTHPAVADVAVIGVPDELAGERAMAFVIRSTSVMSEFSEDDLRDSINDHLEDRLHETHWLGDRLEFVAEIPKSQSGKVLKKILREKAASN
What is the function of this protein?
Acyl-CoA ligase; part of the gene cluster that mediates the biosynthesis of beauveriolides I and III, cyclodepsipeptides acting as inhibitors of the acyl-CoA:cholesterol acyltransferase (PubMed:31926180).  The HR-PKS cm3B initiates the biosynthesis of beauveriolides by iteratively catalyzing the formation of the linear polyketide chain (Probable).  The ATP-dependent acetyl-CoA ligase cm3D converts the polyketide carboxylic acid to a CoA thioester which id shuttled to the first T domain in the NRPS cm3A by the acetyltransferase cm3C (Probable).  Cm3A contains 13 domains and assembles the polyketide chain, L-phenylalanine, L-alanine, and D-leucine (or D-allo-isoleucine) to form beauveriolide I (or beauveriolide III).  The production of both beauveriolides I and III suggests the substrate adaptability of cm3B, using different amino acids as substrates (Probable).
What are the official names of this protein?
Acyl-CoA ligase cm3C, Beauveriolides biosynthesis cluster protein C, Cyclodepsipeptides cm3 biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: KGUA_PARMW
Sequence: MGTLTVITGPSGVGKGTLVQRLLARNPSIWVSVSATTRAPREGEREGESYFFHSRERFDALVQEGGLLEWAEFAGNCYGTPRAPVEQQLQAGRPVLLEIELEGARQVRRSFSKARQIFLAPPSFEELERRIRGRGTDSEDAIQQRLLRAREELSAQGEFDAVVVNDDLDQALLKLEGLMGLG
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZMP to dZDP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCND_LACLC
Sequence: MFDKKLLESSELYDKRYRNFSTLIILPLFILLVGGVIFTFFAHKELTVISTGSIEPTKIVAKIQSTNANPIIENNLKEGEAVKENSLLLKYNGTPEQTQLSELLTQKKQALDKKVQLDLLQRSLTNEKNEFPTADSFGYEKSFENYEAQVKSLEATIQKSNQAVEDQNKSTESQKQAIQNQVATLQQAIQNYSEIENAVSSGGGVSQDNPYLSQYNSYQAQQATLEADLKNQKNPDETAKQAAKSQEESLKSQFLSGLASSKDSLKSQIQSFNVQESSLTGSNAYDNSQSSQILTLKSQALSASNKEMTDLNSTLTDLETKISLQKQDDQYSQVFAEQAGVLHVLPDILGMKKIPIGTPIAEIYPLLKSETQVNLTSYIPSTQISGMKVGQKVRFTVQQNLPQPEILTGIINQIDSAPTAFKEGNAYKVSATTTINAKDLPNIRYGLQGKTVTIIGKKTYFNYFLDKIMGRGNQ
What is the function of this protein?
Involved in the secretion of lactococcin A.
What are the official names of this protein?
Lactococcin A secretion protein LcnD.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: UBIB_SHEB5
Sequence: MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLAMQELGPVYIKLGQMLSTRRDLLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESLFDDFNEIPLASASISQVHTATLKSNGKDVVLKVLRPNVETKIQADLQLMSQTAKLIEYLLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLMVMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQLVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSSQQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGWRSRPKNRKF
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXC_VESOH
Sequence: MIKQRTIKKEVKARGIGIHSGSVVNMTLIPAKEDHGVVFRRMDVGDKLVRAHSAFVNEVVLSTGLENKGVKVSTVEHLMSAFSALGIDNVLVELDSFEVPIMDGSSAPFIFLVQSAGIEEQSTHKKFFVIKDTIRVENGDSWAQVSKYEGFKVSLEIDFDHKKVKESGEKLSINFSKQSYLKEISRARTFGYMKDVEMMQRQNLALGASMDNAIALSDDDVLNEDGMRYQNEFVKHKILDIVGDLYLLGSNLIGHYEGYKTGHLLNDQLLSTILAKPDTWSIETFEEDNSPIQFYSEDWQNSL
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: IF1_LISMF
Sequence: MAKEDVIEVEGVVQETLPNAMFNVELENGHKVLATVSGKIRMHYIRILPGDKVTVELSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAPT1_YEAST
Sequence: MQHKDTAVAKDTAKKRLLRRNSAPSAIHIISRLDKKWSFLWNTIDRHNIVEEQDESSAAKSEEEHEDDYELEQLLNMIRIPMFLEKFMLFALLTSLDCFLYYFTVLPIRLIKGYVKQFKSYRQHYRLQQRSGHKNKIPFRYRITSREYKERCMIFIIVISSILLSKLDTSKLYHRIKRQSTMKLYMLFSVLEMADKMLASLGQSLLTVMLSRKNSERILLHKCLLVSMSLTYVTIHGYVLVYQAISLNIAVNSYSNALLTLLLSMQFAEIKSSVLKKFDKEGFFQITIADVVERFKLTLLLSITGLRNLQSWSSSLSNTSINFWSPRSTLSIVINILCGPMVSVVGSEVLVDWAKHAYITKFNRIRPQIYDKFYYIIYKDYSTRTHKLEDRLGLPLPAFVVLFIVMVRPTLFKSSEPSYLPSLFRILFMGASVFLLALLAKFTLDLILIKWSKRIEQRFRDQAFNTVVTEEEYVPGLLSGGMGKVDVSTRIALHSDYNKENRIETESVSPMRKRKTTLTAECTPPSLNDIRRQKDSKNPRSLENVARYKMVSKRIW
What is the function of this protein?
May be involved in membrane protein folding.
What are the official names of this protein?
Endoplasmic reticulum membrane protein 65, 65 kDa endoplasmic reticulum membrane protein.
What is the protein family that this protein belongs to?
Belongs to the TAPT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion.
Protein: EFCC1_HUMAN
Sequence: MEPVSTGAEAGMEGAGGDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDCRGAGRLPRADFRALCAVLGLRAEGATTAGQAAGDGNSRDVTPGDAAAELATDGDSDTDEEARLALRAEPPELTFRQFHARLCGYFGTRAGPRLPRGALSEHIETQIRLRRPRRRRRPPCAPGPDSGPDCERVARLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQASTHEMGHGGPEAAVRELRQAQGALAAAEARAGRLRRGQAEVRRRAEEARQVVLRSLHRVRELEALAQQVPGLQRWVRRLEAELQRYRSEDSQLPTPQLANPEPGDKSNEPEDAGTRDPDPTPEGAWQSDSSSGSRALDEVDEQLFRSVEGQAASDEEEVEEERWQEEKKTPAAEAKTLLARLSSCRGRCDDQTAEKLMTYFGHFGGANHAHTLGELEACIAMLVEQLRTQGCGGRTLGTSEEEAELQQKVEENEHLRLELQMVETERVRLSLLEEKLVDVLQLLQRLRDLNISKRALGKILLSTLDAFRDPTHEGRPSPAAILDALHQALAACQLLRRQPSAPASAAAALTNPLLVSC
What are the official names of this protein?
EF-hand and coiled-coil domain-containing protein 1, Coiled-coil domain-containing protein 48.
Protein: SMC1B_MOUSE
Sequence: MGHLELLLVENFKSWRGRQVIGPFKRFTCIIGPNGSGKSNVMDALSFVMGEKTTNLRVKNIQELIHGAHTGKPVSSSASVTIIYIEDSGEEKTFTRIIRGGCSEYHFGDKPVSRSVYVAQLENIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFHFNVKKNVAAERKHAKIEKEEAEHYQNLLEELKINKIQLMLFQLYYNEEKINVLNTELEQMDGNLSVVKDTLSHHENIFKAKKKDYGMLTRQLQQTAKELKSVEAILNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCSKQEDGIRALVAELADLDRAWKSFEKQMEEKILQKGRDIELENSQLDRYKLLKEQVRRKVGIMTQQLEKLQWEQKAEKERLAFEKRRHGDTQGNLKQIKEQIEEHKKRIEKLEEYTKTCMDCLEDKKQQEEALKKEIENTKSRMSEVNEELSLIRNELQNAGIDNHEGKRQQKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKIAKDCIRFLKAERAEPETFLALDYLDIKPINERLREIKGCKMMIDVIKTQFPQLKKVIQFVCGNGLVCETVEEARHIAFGGPERRKAVALDGTLFLKSGVISGGSSDLKHKALCWDEKELHNLRDKRSQLVQELKELMKTLRKETDLKQIQTLVQGTNTRLKYSQNELEMIKKKHLATFYREQSQLQSELLNIDSQCTMLSEGINKQQQKIEEFQDKIDEVEDDIFQDFCEEIGVENIREFENKHVKQQQENDQKRLEFEKQKTRLNIQLEYSRNQLKKKLNNIDTLKTTIQKGKEDIDNLKKTEEECLKIVEELMVKQEQIKEVLATQSSNIEKIHIQIEEERKKVLAVDREVGKLQKEVVIIQGSLEQKLLEKHNLLLDCKVQDIDISLVLGSLEDIIEMELTETESTQATADIYEKEASIQIDYSPLREDLKALQSDKEVEAHLTLLLQQVASQENTLLKTTAPNLRAQENLKTVRDKFQESADVFEASRKEARICRQEFEQVKRRRYDAFSQCFEHISVSIDQIYKKLCRNNSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQSQEQFQMIIISLKEEFYSKADALIGVYPEHNECMFSHVLTLDLSKYPDTEDQEGSRSHRKPRVPRVSMSPKSPQSR
What is the function of this protein?
Meiosis-specific component of cohesin complex.  Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment.  Contributes to axial element (AE) formation and the organization of chromatin loops along the AE.  Plays a key role in synapsis, recombination and chromosome movements.  The cohesin complex is required for the cohesion of sister chromatids after DNA replication.  The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.  The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
What are the official names of this protein?
Structural maintenance of chromosomes protein 1B, SMC protein 1B, SMC-1-beta, SMC-1B.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. In prophase I stage of meiosis, localizes along the AE of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. Remains chromatin associated at the centromeres up to metaphase II. At anaphase II, dissociates from centromeres, allowing chromosomes segregation.
Protein: TYSY_METBU
Sequence: MTHDAAIGRLIKARTISDAWYRGLNVIWNHGSLITDERGSQIREFMNLMVVIEDPYSNEIPEDSAWNHERLEEYAKQLITGENAQDFEYTYGQRLRNWDGKVDQIEYVIEKLTNNKTTRRATAVTWVPTIDTKVDEVPCMIIDDFKIRDDTVHLTTLFRSHDFAGAYPANLYGLSKLLEYVADKVGLAPGTITTMSVSAHIYDHDWDKIEKIIKGVQ
What is the function of this protein?
May catalyze the biosynthesis of dTMP using an unknown cosubstrate.
What are the official names of this protein?
Putative thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM_MYCCH
Sequence: QHSKHHAAYVAGVNSAVAKLEEAREKGDHAAIFLNEKNLAFHLGGHVNHSIWWKNLSPNGGDKPTGDLAAAIDDQFGSFDKFQAQFTAAANGLQGSGWAVLGYDSLGQKLLTFQLYDQQANVPLGIIPLLQVDMWEHA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.