PharMolix/UniProtQA huggingface dataset:
Protein: SNG4_HUMAN
Sequence: MHIPKSLQELANSEAVQFLRRPKTITRVFEGVFSLIVFSSLLTDGYQNKMESPQLHCILNSNSVACSFAVGAGFLAFLSCLAFLVLDTQETRIAGTRFKTAFQLLDFILAVLWAVVWFMGFCFLANQWQHSPPKEFLLGSSSAQAAIAFTFFSILVWIFQAYLAFQDLRNDAPVPYKRFLDEGGMVLTTLPLPSANSPVNMPTTGPNSLSYASSALSPCLTAPKSPRLAMMPDN
What are the official names of this protein?
Synaptogyrin-4.
What is the protein family that this protein belongs to?
Belongs to the synaptogyrin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MED18_EMENI
Sequence: MHELLLFASVPSHQHHELLQQLTGLTAMQPRHCLERRLIFKATRKPDLANMRSGTGQGPDIVRLNKMLNGQMFYTQVVGPLSEADFDGKPSSSDSQDVSMSGTHEAAGSSYDYDSQPWRLEFRDTPEAGFRSTITARLAASAALPKGDVVPSMNAWGYSFVTEYVVEGDMFIYNDIVIFLHRVLQYPATGQEPHEPRRQLPSFRDLAPLEKTGSYILQAAITVQDGSNQELMRTASQHLFGLREQLKSAVRLEHADRLSLDTRAR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y028_MYCPN
Sequence: MQFKYLFTVIIPTYNCGQYIPKALDSLLLQGEYFTKTQVLIVNDGSTDNTKQIVEPYTQQYSNIEYLEKPNGNWGSVVNFVKQNQLAKGQYITVLDSDDYFLANAFQRVAAHFGHDMIVSAFYCYISPKRRRFLKPYFGKTGVIEQKTKLRTPHSQPLAKFYRHEIFHLLDPLKEKLFYQDCLLYHNAINKVQSVFYICEPLAVWYATRPGNSTTMPWNNADKFQAWCDLLKQMNLYGAGIVIYIYTMLPGFLKELKRQQLVLDLAKKPAYTWLPQPLAFLFGGLMALRTRKYIRYPKN
What are the official names of this protein?
Uncharacterized glycosyltransferase MG025 homolog.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: SYS_EHRRG
Sequence: MHDIDFIKNNPELFDEAMQNRNFGKIAHKIIELSANKKHTLTQLYSLQKERNNITQEIEKLKKDNIQCDTQIELSKEITKKINHINNMIKTDSELIDLLNILPNIPDKKVPIGKDENDNIEIRRYGKKVDFKFPPKTHYELGENLNLMDFKQAAKLSGSRFVILKSQLAQLDRALANFMLDVHTQEFGYSEISHPVLVHESAMYGVGQLPKFADDSFKTTDNFRLIPTSEVALTNLVSNANINANELPIRLTACSQCFRSEAGSAGKDVRGMMRQHQFNKVELVSIVTEEQSELELERMTQVAEEILKKLELPYRVMMLCTGDLGFSASITYDIEVWIPSQNQYREISSCSNCKAFQARRMNAKYHTISNGNKVNKFVHTLNGSALAIGRTIIAILENYQNQDGSITIPHVLRKYMNNQDIIKKQ
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_BRUSI
Sequence: MSITAERKQALIKEYATKEGDTGSPEVQVAVLSERIANLTEHFKGHKNDNHSRRGLLKLVSQRRRLLDYVKGVDHARYQALITRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YIDD_HERAR
Sequence: MKTILLLLVRAYQLGISPFLGQNCRFYPSCSAYAFEAIGEYGALKGSFLATKRLCKCHPWHPGGVDPVPKKSSSKKTSSTTACGCGHS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VM3BG_BOTAL
Sequence: SISACNGLKGHFLIEPLKLSDSEKTDLLNRSHDNAQLSPINLVVAVIMAHEMGHGMVLPGTK
What is the function of this protein?
Snake venom Zinc metalloproteinase that inhibits ADP-induced platelet aggregation and inhibits the alpha-5/beta-1 (ITGA5/ITGB1) integrin, a fibronectin receptor.  Has caseinolytic activity.  Induces the detachment of cells that are bound to fibronectin.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like BaG, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIc sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LDH2_BACAN
Sequence: MKKGINRVVLVGTGAVGCSYAYSMINQGVAEEFVLVDVNEAKAEGEAMDLSHAVPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGIFLIATNPVDILTYVTWKESGLPKERVIGSGTTLDSARFRYMLGDYLDVDPRNVHAYIVGEHGDTELPVWSHATIGVQKLETILANNEQYKQEDLDKIFENVRDAAYHIIERKGATYYGIGMSLLRVTKAILNNENSVLTVSAYLEGQYGEKDAYVGVPAVINREGVREIVELELNEEEKAKFAHSVKVLKETMAPVL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R1AB_CVTMI
Sequence: FNKFGKARLYYEMSLEEQDQLFESTKKNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQFHQKILKSIVNTRNAPVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRAMPNLLRITASLVLARKHTNCCTWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDATTAYANSVFNIIQATSANVARLLSVITRDIVYDDIKSLQYELYQQVYRRVNFDPAFVEKFYSYLCKNFSLMIFADDGVVCYNNTLAKQGLVADISGFREILYYQNNVYMADSKCWVEPDLEKGPHEF
What is the function of this protein?
The replicase polyprotein of coronaviruses is a multifunctional protein: it contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products.
What are the official names of this protein?
Replicase polyprotein 1ab, pp1ab, ORF1ab polyprotein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses polyprotein 1ab family.
Protein: RPOZ_XANOR
Sequence: MARITVEDCLEVVNNRFELVMMASKRARQLANGVQPLIENAAASDKPTVMALREIAARRIDNALIDEVEKAERERAEREALEWAAAEVVADEDMSKNDD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MATK_TRIBU
Sequence: MKEYRVYLERARFFQQDFLYPLIFREYIYGLAYSHKDPRSIFVENGGYDNKYSLLNVKRLITRMYQQNHLIISTNDSNKNPFFGYNKNFDFQIIAEGFAILVEIPFLPQLSSSLEEAEIIKSYKNVRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDVSFFHLLRLFLYDFSNWIPTKKSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSSHLRLKSFSVFFERIFFYAKREHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWNHYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPFIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICRNLCHYYHGSSTKKSLYRIKYILRLSCIKTLACKHKSTVRAFLNRSGSEELLEEFFTEEEEILPWKFQILTLLCHSQSFSLHRYERKYRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IOLE_ALKCK
Sequence: MANRKIRWGIAPIGWRNDDIPEIGAENTLSHLLGDIVVARFEGTEAGGFFPEPQILNKELQLRNLKVAGKWFSSYIIRDGIASAAQAFDTHCQFLQAIGAEMAIVSEQTYSIQGLEANIFRDKPTFSKEEWKCLYEGLEELGAIAHSYGLTLAFHPHLGTGVQTKAEVDQLMAHTDPSLVSLLYDTGHAYVSDGAFLPLLDDYMDRIKHVHFKDVRSEVTDACRRDGLSFQQAFLKGMFTVPGDGCIDFTKVYRRLIRGGYDGWIVVEAEQDPNIAHPLEYALKARRYIDSYLLAGGEKQATI
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: MNME_ENDTX
Sequence: MNYLKEDTIAALSTAAGKSAIAVIRLSGENSFQIIGKIFKTHSKPEQQVKHGYITDGIEKKDEVLCTFFKAPHTYTGENLVEIAAHGNPVIINEILNLLYKNGARPAGPGEFTYRAFLNDKMNLAEAEAVCALITSKTEMSAKAALNSLSGEFSSKIKNIRDAVTNLIASMEANLDHPDEDNMFLSRSEKLSRFDSCIKDVQNLLNSYKTGKILQYGIKVVIIGKPNAGKSSLLNAILGKNRAIVTDIAGTTTDTVEETIDCCGIPLIITDTAGIREHSENLIEILGQAKTREAVCKADILIWLFDSSSEPDCNDAKIADFLKKSDLNIPIICVLNKSDLPPLFSSSLLNRENKVKVKISAKTGVGIADLLDEIVKIAGVSESKNDYLMINTRHFILLQNTLESLIRTKQSLSAKDADEIACFEALSAQISLNEILGINVKQDILDTIFSTFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IEND1_USTMA
Sequence: MKTRLFNFTKWWLTGFTQADGGFVVNFDARKQGNLPYYPRPSFVLTQNIREEQMMIELHGVGKLYYSRNEINIVVRSQDDITNVIIPHFDNYSLRGHKLSSYFLFKEVVLMMNNGKHLSPFLQILELCYFTNHTTRRTLDTKKAILDKIYNKFGFVQFEPIIESNLSKPNSNPINNDYMVGLVDGDGSFNFGFKSTRRRIVPNFTIVQGVEDRSVLEDVQSYLDCGKVYDLQSQTSRYQVENVTDLVEKVLPEFKENKFNTTKKDYTL
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded DNA endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SMP3_ASPOR
Sequence: MWRRTYLLLLVIRVYFALSPSYLHPDENFQGPEVFAGRVLSYPSKLPWEFTADKPIRSVFPLWPIYDVPISLLKWFYAETGAPTPPPPQVIYYVLRGVMFLLGFVLEDWAVYELVPFARHRRATVVLVASSYVTWTYQTHTFSNSLETLLVAWGLVLIRRIVVNKRRSSVFSCAVLAFIAVAGVFNRITFPAFLAIPGLQLLPHFRRKSVSPPVSLFSFVGFGIFFFGIAVLVDTAFYRPSATLWDALHSPIITPINNLLYNSDSSNLALHGLHPHYQHFLVNLPQLLGPAYAMMAISLWGLPVIPTWLKNARAVSALSATVILSIFPHQEPRFLIPCVPLLLSCFRVSKSRLFLAVWMIFNAALGFLMGIYHQGGVVPAQLAMPSIISASSVESNDALPGEIPVVSATVFWWKTYSPPLWLLGTNDNSSLNIETRDLMGVPGPNLIEELEKLLPPCNVAGSKQAGSVFVVAPKSAAFLDRYTFLPSSSSVSSALELHELWSYRKHINLDDLDFGTEGVYPTLRRVIGRRGLAVWRAKRAGCN
What is the function of this protein?
Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly.  The presence of a fourth mannose in GPI is essential in fungi (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 4, GPI mannosyltransferase IV, GPI-MT-IV.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ASSY_BACCR
Sequence: MEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKALSVGAIKSYMIDVQEEFANEYALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGATAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENDVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLNGTAYSLAELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLTHVKEVAHFKPVIEQKITELIYNGLWFSPLKQALHAFLQETQKNVTGTVRVKLFKGHAIVEGRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_PSYIN
Sequence: MRLFVFFMLCLLVLLQYHLWFGKNGLGDRHNLQEEVTLILENNSELRQRNQMMFSEIKDLKEGTDAIEERARNELGLVKEGETFFRIVPKED
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: RT04_MARPO
Sequence: MFASRFKVCRQILENVWQTKKLTLKQKFLISELQKQKKNKKQSDFSIQLQTIKKLSLFYGNLPIKKMQRAKTHTYIDKKNSLLFNIEKRLDVILVRLNFCSTMFQARQLISHKNICVNYKKVNIPGFQVSNGDLISIQENSLDFFKSNIRKNFQTNRIRRMKPNHLEVNYKTLKAVVLYEPQQIQFPYKIDLDLLD
What are the official names of this protein?
Ribosomal protein S4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RRF_CLOK1
Sequence: MIKDILNKADEKMNKTVDVLVKELASMKAGRANPAILDKIEVEYYGAMTPISQLAGISIPEARILAIQPWDKSALKSIEKAILKSDLGINPSNDGEIIRLIIPELTEETRKNIVKNIKKTGEDSKVAIRGIRRECNDKFKALKKKNDISEDEIKKGEEQIQKKTDIFIKNIDAILEKKEKEIMSL
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_FRATH
Sequence: MSKLNAYFGEYGGQFVPQILVPALDQLEQEFIKAQADESFKQEFKELLQEYAGRPTALTKTRNIVKNTRTKLYLKREDLLHGGAHKTNQVLGQALLVKRMGKKEIIAETGAGQHGVATALACALLDLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVHSGSATLKDACNEALRDWSANYSKAHYLLGTAAGPHPFPTIVREFQRMIGEETKQQMLAKEGRLPDAVIACVGGGSNAIGMFADFIDEKNVKLIGVEPAGKGIETGEHGAPLKHGKTGIFFGMKAPLMQNSDGQIEESYSISAGLDFPSVGPQHAHLLAIGRAKYASATDDEALDAFKLLCKKEGIIPALESSHALAHALKLAYEDPNKEQLLVVNLSGRGDKDIFTVHDILKEKGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SYT_THEPD
Sequence: MKTLLIHAKHFEYEAREKALDAAESIDGNRSGSFENALVVFVTVEKGDGSSQDVVEEAAADVLDVFRRVGASRVVVYPYAHLSDDLADPEEAKRVLSQLAERISSAGVPVSRAPFGWYKRFSVECYGHPLSELSRTIKPGRRVRPGYADFAVMFPDGRIVGIEELRAEELPEDFVALLEAEVFKKKREGGEPKYLEYCRKFGFEWEPMSDLGHMRYGPEATIMLDAVAEYAWQCARSLGIPVYKVRGTNTFNLSFKPVAQHAQLFGDRLYQMEVDEKKLILRYAACHQQFAMVKDWEISYRDLPFGAFEVADSYRLEQPGELLLCFRLRKFYMPDLHVFCKDLAEAMEVSFRIHSKIYEEIRKLGRDYVSIYNLTRSFLEQHRDYLKRLVEMEGKPVLLHFVPEGKYYWVINVEYNIIDELGRPREIGTFQIDVGNAERFGITYVDENNTRRYPVIIHTAIIGSLERYVFAVLDTAAKKARAGEVPSLPLWLSPVQVRVIPHSSEYLKLADSIADKLEEQGIRVDVDDREESLAKRIRDAEVKWIPYVVVVGKREAESGKLTVRVRGQGQYEMSLEELVGRLVSELKGYPRVSAALPRYVSARPRYSP
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_ACIBS
Sequence: MTQQNAQSTSEPTISENDLIAQRHAKLKQIQDVAKETGKSPWPNTFKREHYAADLQEQFKDQSKEQIESAEHVYVKVAGRVMLNRGSFMVIQDMTGRIQLYVDRKGLPKDTLETIKGLDLGDIIAAEGYIGRSGKGDLYVHLEGFELLTKSLRPLPDKFHGLNDTEVKYRKRYLDLIVNEETRKTFEIRAKVVAGIRAFLTNERFMEVETPMMHVIPGGASARPFETHHNALDMPLFLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSTRHNPEFTMIEFYQAYADYKDLMALTENMLEKLALDILGTTDVPYQGEVFSFKGPFKKISMFDAILENNPQFTPENVGDREFLAKFVREELKEEVKPGFGLGKLQTIVFEETVETKLRQPTFITEYPAETSPLARRNDDNPHITDRFEFFIGGRELANGFSELNDPIDQAERFQAQVAEKDAGDDEAMHYDAEFVEALEYGLPPTAGEGIGIDRLVMLFADAPSIRDVILFPHMRRKEG
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_CAMC1
Sequence: MTKQEYEKAVDTLNAWAKAYYDEDEPLASDEEYDALYHAVLAFEQANPSEISLFSPTKRVGGGVKEGFSKASHIKRMWSMEDIFSLGELDAWLKRGEKENLTFVAEPKFDGASLNLLYENGVLVRAITRGDGVTGEDVTQNARTISSVPKSISYKGLIEIRGEVVIRKDDFELLNMERAKEGEAPLSNPRNAAAGSLRQLDSAVTAKRKLLFIPWGVGEQSLGLKDHSEVMKFVRDLGFERDDFFKILKKDELEAAYNELLANRDSKSVMMDGMVIRVNDLARCEQLGYTVKFPKFMVAFKFPAIEKVTRLKDVALQVGRSGVVTPVGVLDEVNIDGANVKSATLHNFDEIERLGVMKNDYIGIIRSGDVIPKITKVFKDRRDGSEQAIERPKFCPVCGSHLLDEGVFVKCQNLSCRARVVGSIIHYASKKCLNIDGLGDAIVNLLFDKGLIACIKDIYGLKFDDLMSLEGFKEKKVNNLLNAIEASKGAELSRFITGLGCEHIGEVAAKKLASSFGLDWLDASFEELTALEGFGVEMANSLIDFAEVNRDEILALSQIVQPSVTQVQSISNALSGKTVVITGTLSRPRDEIKAELESFGAKVSGSVSKKTDFVLAGEEAGSKLDKANELGVLVIDESEYERLKLEV
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RK20_BIGNA
Sequence: MTRVKRGKITCRTRKKRMQSVKGFRGAWSTLSRPAMQGSLRALNYSYKHRRKNVKTFRRLSIVRFNALIRNSGLPFTYNRLIALINLYNCRLNRNVLSQLGIRDSNTFTKLMKFYYH
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GC_MEHVH
Sequence: MVSNMRVLRVLRLTGWVGIFLVLSLQQTSCAGLPHNVDTHHILTFNPSPISADGVPLSEVPNSPTTELSTTVATKTAVPTTESTSSSEAHRNSSHKIPDIICDREEVFVFLNNTGRILCDLIVDPPSDDEWSNFALDVTFNPIEYHANEKNVEVARVAGLYGVPGSDYAYPRKSELISSIRRDPQGSFWTSPTPRGNKYFIWINKTMHTMGVEVRNVDYKDNGYFQVILRDRFNRPLVEKHIYMRVCQRPASVDVLAPPVLSGENYKASCIVRHFYPPGSVYVSWRRNGNIATPRKDRDGSFWWFESGRGATLVSTITLGNSGLESPPKVSCLVAWRQGDMISTSNATAVPTVYYHPRISLAFKDGYAICTIECVPSGITVRWLVHDEPQPNTTYDTVVTGLCRTIDRYRNLASRIPVQDNWAKTKYTCRLIGYPFDVDRFQNSEYYDATPSARGMPMIVTITAVLGLALFLGIGIIITALCFYLPGRN
What are the official names of this protein?
Envelope glycoprotein C homolog, A antigen, Glycoprotein A.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein C family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: ICP34_HHV1D
Sequence: MARRRRRHRGPRRPRPPGPTGAVPTAQSQVTSTPNSEPVVRSAPAAAPPPPPAGGPPPSCSLLLRQWLQVPESASDDDDDDDWPDSPPPEPAPEARPTAAAPRPRSPPPGAGPGGGADPSHPPSRPFRLPPRLALRLRVTAEHLARLRLRRAGGEGAPEPPATPATPATPATPATPATPARVRFSPHVRVRHLVVWASAARLARRGSWARERADRARFRRRVAEAEAVIGPCLGPKARARALARGAGPANSV
What is the function of this protein?
Plays essential roles in viral nuclear egress to mediate capsid transit across the nuclear membrane and also in the inhibition of host immune response.  Facilitates nuclear egress cooperatively with host C1QBP and protein kinase C/PKC to induce lamin A/C phosphorylation and subsequent reorganization.  In turn, lamina disassembles and nuclear egress occurs.  Recruits the serine/threonine protein phosphatase PPP1CA/PP1-alpha to dephosphorylate the translation initiation factor eIF-2A, thereby couteracting the host shutoff of protein synthesis involving double-stranded RNA-dependent protein kinase EIF2AK2/PKR.  In turn, controls host IRF3 activation and subsequently inhibits host interferon response.  Controls the DNA sensing pathway by interacting with and inhibiting host STING/TMEM173.  Also down-modulates the host MHC class II proteins cell surface expression.  Acts as a neurovirulence factor that has a profound effect on the growth of the virus in central nervous system tissue, by interqcting with host BECN1 and thereby antagonizing the host autophagy response.
What are the official names of this protein?
Neurovirulence factor ICP34.5, Infected cell protein 34.5, protein gamma(1)34.5.
What is the protein family that this protein belongs to?
Belongs to the PPP1R15 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host nucleus, host nucleolus. Virion. Note=At early times in infection, colocalizes with PCNA and replication proteins in the host cell nucleus, before accumulating in the host cytoplasm by 8 to 12 hours post-infection.
Protein: CCME_LEGPL
Sequence: MTPVRRRKLFILLFALSVLSAAAALVLYALRQNISLFYTPTQIVAGEAPAKHHIRVGGMVEANSIVRAKKGLAVQFKITDFENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHATQVLAKHDANYMPPQVKSALADKVKQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: MURB_BURTA
Sequence: MPMSRPDSSVQLLSDYSLRAHNTFGFDVRARVAARIGSPEQFASLARDPRVAGLDALVLGGGSNVVFTRDFDGLVLLDEIRGRALAREDDDAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAPIQNIGAYGIEMKERFASLRAVELATGEIVEFDAARCAFGYRDSFFKREGRGRFAIVSVTFRLPKVWAPRLGYADVARELAARGIDASRASARDVFDAVVAIRRAKLPDPLELGNAGSFFKNPVIDAHAYAALRAREPDVASYPQPDGRMKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGASGADVLALARAIQRDVLERFGVELEMEPVCL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_BORBR
Sequence: MSKPALRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQKALKGVIMELEDCAFPLLHEVTAHSDPRTAFKDADVALLVGARPRGPGMERKDLLSVNAQIFTAQGRALNDVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALSQLSAKSGKRVADIEKLIVWGNHSPTMYPDFRFATVGGQGLTQLINDDAWNRDTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGIPSDGSYGIPEGIIYGFPVVTENGEYKMIKDLEIDAFSRERLDFTLKELLEERDGVKDLLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.