PharMolix/UniProtQA huggingface dataset:
Protein: TOP1_HELPY
Sequence: MKHLIIVESPAKAKTIKNFLDKNYEVIASKGHVRDLSKFALGIKIDETGFTPNYVVDKDHKELVKQIIELSKKASITYIATDEDREGEAIGYHVACLIGGKLESYPRIVFHEITQNAILNALKTPRKIDMSKVNAQQARRFLDRIVGFKLSSLIASKITKGLSAGRVQSAALKLVIDKEREIKAFKPLTYFTLDAYFESHLEAQLISYKGNKLKAQELIDEKKAQEIKNELEKESYAISSIVKKSKKSPTPPPFMTSTLQQSASSLLGFSPTKTMSIAQKLYEGVATPQGVMGVITYMRTDSLNIAKEALEEARNKILKDYGKDYLPPKAKVYSSKNKNAQEAHEAIRPTSIILEPNALKDYLKPEELRLYTLIYKRFLASQMQDALFESQSVVVACEKGEFKASGRKLLFDGYYKILGNDDKDKLLPNLKENDPIKLEKLESNAHVTEPPARYSEASLIKVLESLGIGRPSTYAPTISLLQNRDYIKVEKKQISALESAFKVIEILEKHFEEIVDSKFSASLEEELDNIAQNKADYQQVLKDFYYPFMDKIEAGKKNIISQKVHEKTGQSCPKCGGELVKKNSRYGEFIACNNYPKCKYVKQTESANDEADQELCEKCGGEMVQKFSRNGAFLACNNYPECKNTKSLKNTPNAKETIEGVKCPECGGDIALKRSKKGSFYGCNNYPKCNFLSNHKPINKRCEKCHYLMSERIYRKKKAHECIKCKERVFLEEDNG
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: CA050_HUMAN
Sequence: MEDAAAPGRTEGVLERQGAPPAAGQGGALVELTPTPGGLALVSPYHTHRAGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDAHRDANLHHVACNIVKKPGNIYYLYKRESGQQYFSIISPKEWGTSCPHDFLGAYKLQHDLSWTPYEDIEKQDAKISMMDTLLSQSVALPPCTEPNFQGLTH
What are the official names of this protein?
Uncharacterized protein C1orf50.
Protein: NUOH_PSEPF
Sequence: MTWFTPEVIDVILTVIKAIVILLAVVVAGALLSFVERRLLGWWQDRYGPNRVGPFGMFQIAADMLKMFFKEDWTPPFADKVIFTLAPVVAMSALLIAFAIIPITPTWGVADLNIGLLFFFAMAGLSVYAVLFAGWSSNNKFALLGSLRASAQTVSYEVFMGLALMGIVVQVGSFNMRDIVEYQAQNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFVGEYIGIILISALLVTLFFGGWHGPFGILPQLSFVWFALKTAFFILLFILLRASIPRPRYDQVMDFSWKFCLPLTLINLLVTAAIVLWNTPAVAVQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ODF3A_XENLA
Sequence: MGTDLWVGTWRPHRPRGPIAAFYSSPGPKYSLPGNTGFVSHDPSRHRAPAYSMGNRRFKLVDDCSPGPGYLVPSNITVKGKDGTPAYSIYGRPRDISSFRTPGPGSYSPERAGKSAYRSAPTYSLGERTKTFGNDQTPGPAAYMLPSVIGPRIVNRSSAPNYSMTGRSKIGSFHEDLQKTPGPGTYRVIDPGTYKHKPPQYSMTARNVLPGDTTIKPGPGAYSPEKVVMSKAQAPNFSFGIRHSEYVAPLIVDVAD
What are the official names of this protein?
Outer dense fiber protein 3, Outer dense fiber of sperm tails protein 3.
What is the protein family that this protein belongs to?
Belongs to the ODF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Expressed in the cytoplasmic lobe of spermatids.
Protein: HIRA_CHICK
Sequence: MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMAPVLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNNGVYLASGGDDKLIMVWKRAAYIGPSTVFGSSSKLTNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKSSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSNIHQSTYGKSLAIMTEAQLSTTIIENPEMLKYQQRQQQQQAEQKNASIREASGAATTAPKVASMVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPISGTLAGSIMSSQNNQQLMSLDSNAANSLNTSKPSAEPTAASIKPTDDAASKDGVNATSVSTAPPASSSSVLTTPSKIEPMKAFDSRFTERSKATSGTAVVTNTNQTVVDRLKDQNLIKDNKPKDILESSSDSEEKIPAAKPLSAPKRKLELEGETVEKKKKGRPRKDSRLVPVTLTVQSPAALASEKDAACISAPALALKLPTPIPQKSFTLQVSSDPSMYLEVENEMTTVGGSKLSRLKCNREGKEWETVLTSRILTAAGSCEIVCVACEKRMLSVFSACGRRLLPPIILNTPISTLHCTGSYIMTLTTAATLSVWDVHKQTVIVRDESLQTILSGSDTTVSQILLTQHGIPVMSMSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQEAMLCSGPLAVIQGRTSNSGRQAARLFSMPHLVQQETTLAYLENQIAAALMLQSSHEYRHWLLIYARYLVNEGFEYRLRELCKDLLGPVHYSRGSQWESTVMGLRKRELLKELLPVIGQNLFQRLFTEYQEQLDIL
What is the function of this protein?
Cooperates with ASF1A to promote replication-independent chromatin assembly (By similarity).  May regulate the transcription of a variety of genes controlling cell growth.
What are the official names of this protein?
Protein HIRA, cHIRA, TUP1-like enhancer of split protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URE1_CITK8
Sequence: MTEISRQAYADMFGPTTGDRVRLADTELWIEVENDLTAYGEEVKFGGGKVIRDGMGQGQMRARACVDLVITNALIVDHWGIVKADIGIKDGRIFAIGKAGNPDIQPNVTIPIGVGTEAIAGEGKIVTAGGVDTHIHWICPQQAEEALVSGVTTMIGGGTGPAAGTNATTCTPGPWYIARMLQAADSLPVNIGFLGKGNGSNPDALREQIAAGAIGLKIHEDWGATPAAIDCALTVAEEMDIQVALHSDTLNESGFVEDTLAAIGDRTIHTFHTEGAGGGHAPDIITACAHPHILPSSTNPTLPYTVNTIDEHLDMLMVCHHLDPDIAEDVAFAESRIRRETIAAEDVLHDLGAFSLTSSDSQAMGRVGEVILRTWQVAHRMKVQRGPLAEETGDNDNQRVKRYIAKYTINPALTHGIAHEVGSVEAGKLADLVLWSPAFFGVKPATLIKGGMIVCAPMGDINASIPTPQPVHYRPMFGALGAARHHCRLTFLSQAAVENGIAQQLNLRSATAVVKGCRTVKKADMIHNSLQPNITVDAQTYEVRIDGEPITSEPADVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIME_MYCTO
Sequence: MCRTLIDGPVRSAIAKVRQIDTTSSTPAAARRVTSPPARETRAAVLLLVLSVGARLAWTYLAPNGANFVDLHVYVSGAASLDHPGTLYGYVYADQTPDFPLPFTYPPFAAVVFYPLHLVPFGLIALLWQVVTMAALYGAVRISQRLMGGTAETGHFAAMLWTAIAIWIEPLRSTFDYGQINVLLMLAALWAVYTPRWWLSGLLVGVASGVKLTPAITAVYLVGVRRLHAAAFSVVVFLATVGVSLLVVGDEARYYFTDLLGDAGRVGPIATSFNQSWRGAISRILGHDAGFGPLVLAAIASTAVLAILAWRALDRSDRLGKLLVVELFGLLLSPISWTHHWVWLVPLMIWLIDGPARERPGARILGWGWLVLTIVGVPWLLSFAQPSIWQIGRPWYLAWAGLVYVVATLATLGWIAASERYVRIRPRRMAN
What is the function of this protein?
Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol tetramannoside (AcPIM4) to generate a monoacyl phosphatidylinositol pentamannoside (AcPIM5).
What are the official names of this protein?
Polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol pentamannoside mannosyltransferase, Alpha-mannosyltransferase, Alpha-ManT, PPM-dependent mannosyltransferase, Polyprenol-phosphate-mannose alpha-mannosyltransferase, PPM alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 87 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VATI_BORBU
Sequence: MIVKMKKVLLLTLSKYKKESLEILRDFGAVHINSCNKNSDSLKKSIDDRRILMQAFSLLKEDGGVKALKSSNGNFLDIAKSIVNLGNEIKEFQDIKRSLLHERNLISVWGNFSLENIDELKESNIYIQFFKIQKSEYKNLLRDPNVNVLLIKNVKNTSYFVSVGEFEQKIEIADEFKFNFDLDYINNKLKVVDEILDQKLTQISLFNKYIDILRDEIKNYDQIVEFEQVLADMQTDXEDFSYITGFVPAESQESLKNAVLKAGFAAQFADPEENDIIPTYIKRKGIANLAAPIFNILETIPGYKERDISFIFMLFFFVFFGMIIGDAAYGVIFFLIGILLSLSFLLKGKPLTPFHGLIFYLSVSSILYGAMTGTWFGSPLILEMFPILNSFKVSYLTEKNSVQNIIFICFSIGVLQISLAHVWNFFRQVKEKPHIHSIAQIGWLMCIVGLYYLVLNLILSQSRFPMYNVVYNVIYFGVALVFVFGKQDGSNFFKCILKSFGGIIEQFLTTVSGFADIISYIRLFAVGLAGLSISASFNTMSIPLLKSSNIGLIVAGIIVILFGHVLNIMLSLLSVIVHGVRLNMLEFSNHLGQEWSGCAYRPFKKMKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit I, V-ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSD2_CANAL
Sequence: MRSSGYLNSNNGSSSSLESTNVNKSTDKNQLYLKVVCNCATDLVPQDTTGTGSESKKAYSSSKSINPVLVVQLNNTIKSTSKKLNTNQPSWNDELYMPLKNQDDSSLLIFSVWDKHTRYKNYLGELRLNVKDIFVDNGNFVDKTELKWYHLNSNTKYHSFVTGSILAGFELVIKNKKKRFHSSYNDKFQQLSIDSDVESAFKKWLSSLTKPTIYSVNNKINPNDQGFYDDELVNEFELESVLTERSKKSHLNVPGGNGLLSVPGDDCHDAGSFSDASFLSDGGYASDASANLFDQKETSSDSKKSRIKSKMRLRRSKQEYENFELASRQVLGVVFIEIVSCEDLPPYKNFTRTSFDMDPFVVVSFGKKTFRTGWKRHTLNPVFNERLAFELLPHESNFSIQFLVLDKDHFSFHDNVAHISLPLRTLTEYATAKPTEGDSSDVNTSDSTSFSQTGNGFTTEDTEFPENDSVQIIENETPSNKQSRKRYLSRKKVVGTQLDLKKFKAMSLSLQLHDQKYIGKYAPKLKIRVRFETYTELRKKFWRVLLEESNSTPENRDSCDYIELISLLDTLGCVNSDELVELFYSNLGKSSWGGDLLTFDEIIDQMETYVNQNVESGKVKIFEFEKCPICNEKRVSKKQDLDIITHFAICASKDWSVVGKLLSSSYVTPTQATKKWFTKALIKLTYGKYKLGGNSANILVQDRMTGIIVEEKMSVYVRLGIRLLYKGLDKARSKRVRILLKNMSIKQGKKFDAPQSKSDIASFIKFHKLDLDECEIDDPSQFATFNDFFYRKLKPGAREIEDEKNSKIVTSPADCRSVVFESIDKATQLWIKGAGFTIPKLIHNDHSMRVSSYTLGIFRLAPQDYHRFHSPVDGVIESIKHIDGEYYTVNPMAIRSELDVFGENVRTIVTIKTKDFGNIYFIAVGAMMVGSIVLTKDTGYEISKGEELGYFKFGGSTVLLLIESDKFKFDTDLVKNSSSGLETLLRVGQSIGHSPDVEEYKRDHISFDKLDKSKQLRLIRVLTGGDLKDKHKLSNWEATKIDMEDFQEIEDEEVFDKDMPDEDASIKSED
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine (By similarity).  Important for virulence (PubMed:20132453).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme 2.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: 2SS8_HELAN
Sequence: MARFSIVFAAAGVLLLVAMAPVSEASTTTIITTIIEENPYGRGRTESGCYQQMEEAEMLNHCGMYLMKNLGERSQVSPRMREEDHKQLCCMQLKNLDEKCMCPAIMMMLNEPMWIRMRDQVMSMAHNLPIECNLMSQPCQM
What is the function of this protein?
This is a 2S seed storage protein.
What are the official names of this protein?
Albumin-8, Methionine-rich 2S protein, SFA8.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: ADCY7_BOVIN
Sequence: MPAKGRYFLNEGEEGPDQDALYEKYRLTSQHGPLLLMLLLVAIAACTTLIVITFSYGDPSRHRAVLGTAFFTLAMFVLLYALVYVECLDRRGLRISALLIWGCLVTLGYVLVFDFDSPRKDTLCLWGRCPSSSFVVFVVYTLLPFSMWGAVTAGLVSSISHLLVLAMHQEDFTSPVGLKLLATAVVFVCGNLTGAFHKHHMQDASHDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAHISMGMKLAIIERLKERGDRRYLPDNNFHNLYVKRHQNVSILYADIVGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPNHARNCVKMGLDMCEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPQPSQHNSKNKGNATLKMRASVRMTRYLESWGAARPFAHLNQRESVSSSETLVSHGRRPKAVPLRRHRTPDRSASPKGRSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFSTFGSIFLEKGFEREYRLAPIPRVRYYFACASLVFVCILLIHVLLLYSMKTLGVSFGLVACVLGLVLGLCFADVFLRCCPALGKLRAIAESVETQPLLRVSLAILTIGSLLVIAVVNLPLMPFRDRGLTAGNETGLRAVSGWEMSPCYLLPYYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNVYPSWQWDCCGHSLGNLTGTNGTLSSSSCSWHLKTMTNFYLVLFYTTLIMLSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVPSGPENQDLERQHAHIGIMVEFSTALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLIDVKGKGELRTYFVCTDTAKFQGLGLN
What is the function of this protein?
Catalyzes the formation of cAMP in response to activation of G protein-coupled receptors.  Functions in signaling cascades activated namely by thrombin and sphingosine 1-phosphate and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G alpha protein with GNA13 (By similarity).  Also, during inflammation, mediates zymosan-induced increase intracellular cAMP, leading to protein kinase A pathway activation in order to modulate innate immune responses through heterotrimeric G proteins G(12/13) (By similarity).  Functions in signaling cascades activated namely by dopamine and C5 alpha chain and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G protein with G beta:gamma complex (By similarity).  Functions, through cAMP response regulation, to keep inflammation under control during bacterial infection by sensing the presence of serum factors, such as the bioactive lysophospholipid (LPA) that regulate LPS-induced TNF-alpha production.  However, it is also required for the optimal functions of B and T cells during adaptive immune responses by regulating cAMP synthesis in both B and T cells (By similarity).
What are the official names of this protein?
Adenylate cyclase type 7, ATP pyrophosphate-lyase 7, Adenylate cyclase type VII, Adenylyl cyclase 7.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL15_STAAC
Sequence: MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGGGVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVVKNEKSGIKILGNGSLDKKLTVKAHKFSASAAEAIDAKGGAHEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: AZOR_SHEB5
Sequence: MSKVLILKSSILGGYSQSAVLIDHLASHWETQGAAITVRDLGGKDVLPMVDGEIASGLRGGAELSARQQEMLALSDTLVAELKANDTIVIAAPMYNFTIPTQLKNWIDFIARAGVTFTYTETGPKGLVEGKRAVLVTTRGGAHKDGPTDHVVPYLKTVLGFIGITNVEVVYAEALNMGPEAHDKGMSEAKHSIEQLKA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: ATPB2_BURMA
Sequence: MADPQATNGTGAVCAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVFVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL23_LEGPL
Sequence: MNAERLMMVLREPHTSEKATVMADKFKQFTFKVLKNATKTEIKLAVEHIFNVKVKSVSVVNVKGKSKRFKQTSGKRSDWKKAFVSLHADQDIDFTVTE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MIP1_SCHPO
Sequence: MNDRISEVSGSSRARRSVLSYGTTETGSDRYTENSNIATENGVDTASSMIDGIQSGFPQPRHGFEEEYNNAEYINMLEQVFYMYYTDKRHRGVISKKNAEPTETIHDWRMRERLKTVSAALLVCLNIGVDPPDVIKPNPAAKYECWIDPFSLPASKALEAIGKNLQQQYETLSMRTRYRHYLDPAIEEVKKLCIGQRRNAKEERILFHYNGHGVPMPTASGEIWVFNKNYTQYIPVSLYDLQSWLGAPCIYVYDCSAAGNIIVNFNRFAEQRDKEALRIAKQNPNVLAMPSHTSCIQLAACGPKETLPMNPDLPADLFTSCLTSPIEISVRWYVLQNPFPNKLNLNMLLKIPGRLQDRRTPLGELNWIFTAITDTIAWNVFPKHLFRRLFRQDLMVAALFRNFLLAERIMLVHSCHPQSSPELPPTHDHPMWNSWDLAIDNCLSQLPDMLDAESKGIAYEYKHSTFFSEQLTAFEVWLSQGLISRKPPDQLPLVLQVLLSQVHRLRALILLSKFLDLGVWAVDLALSIGIFPYVLKLLQSPAIELKPVLVFIWARILAVDDSCQADLLKDNGYGYFVQILNPNSSIFPSSNISEHRAMCAFILSVFCRGFPQGQLACLNPQVLSHCLSHLNSPDSLLRQWACLCISQLWENYSEAKWSGTRDNAHVKLAEIIVDSVPEVRASVLTAFTTFLGFPEKTEEVVAVETYIAIAALAALSDASPLVRHELVIFLSHFVVNYKKQLMVVAYESSLADILEKKNHNSISASTIYETVWQAVLVLAADPSIEISLAAEAIINYVYQSMLNSELRESFLAFLLQHLPALHKASLSKDTDTNSVTSDPKPHPFVPSVSENKILNRSFSLTRSLKGLALSLAGSDRASELLSLNGENKPAESNLNHLTSAKVPGPPAFNELEYQSELDMPLTSYLFDWSRKYFTEPQMRPNEDDEPGSICYNQRLWRRNRNEKLIYRTRPLAEYSTNGRWNQQLMTFNNTIAPRKLMFHQFEDQLITLGDKDIIQVWDWRRNRCLNSFKTSASATTNVTDMQLLNEDDVALLMTGSSDGTIKLYRDYENEKVELVTSWNSLSDLVFGDRNASLLMSWQQNCGHLLVAGDVRVIRIWDASKEICYANLPVRSSNSITSLTSDLVGCNIIVAGFSDGVLRVYDKRLPARDSLTDVWKEHSSEIVNVEMQSSGMRELISASSDGEVKLWDIRMNHSLQTFSTDNSGLTSLTVHSHAPVYATGSSNQSIKIWDTLGQNINTFRENPRFLNQPKPSSLMCLKFHPHHLLLACGDNTDSRVNLYSCTKNEIHTDSPNEF
What is the function of this protein?
Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals.  Tor2 is essential for growth.  Nutrient limitation and environmental stress signals cause inactivation of TORC1.  Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression.  TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake.  Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcription factor ste11 and the meiosis-promoting RNA-binding protein mei2.
What are the official names of this protein?
Target of rapamycin complex 1 subunit mip1, TORC1 subunit mip1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RAPTOR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMLA_YEREN
Sequence: MKGIVLAGGAGTRLHPITRGVSKQLLPVYDKPMIYYPISVLMLAGIQDILIISTPEDLPSFKRLLGDGSQFGIRLQYAKQPSPDGLAQAFIIGEEFIAGERCALVLGDNIYFGQSFGKQLREVASRNDGATVFGYQVVDAERFGVIEFDENFNALSIEEKPQKPKSDWAVTGLYFYDKDVVEMAKEIKPSERGELEITTLNEMYLAKGKLRVELLGRGFAWLDTGTHDSLIDASLFIHTIEKRQGFKVACLEEIAYQNQWLSREKLNELAEALNKTYYGQYLLKLAKES
What is the function of this protein?
Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.
What are the official names of this protein?
Glucose-1-phosphate thymidylyltransferase, dTDP-glucose pyrophosphorylase, dTDP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the glucose-1-phosphate thymidylyltransferase family.
Protein: TRM6_CRYNB
Sequence: MTEKQQNSQQPSQLDSTASISALPPQLQQPAAGITGAPGNAEATTSEPPSTKRPRKAIESSEPLTEVILRRLTTIKEGDTVLLRLPSDLVKSVVVQGDNLVQLGKYGAFPASQLIGLHYDITYEIVSSSGSGASTPQPQSLDFSTEETQSKKGNKKNKNKGKDTAAVSKNNPGWNNILRPLKRQLVVDAVIDDIVETNEFIEDLSETEKTTLSHDEIAELRAQGCTPEEIIQAQIARHEKFGLKTDFSKEKWRRRKEKKFYQTVQPLAPSIPNVLYHYNLRSPQSILHLRDDTLSQLLTMANVRPGGRYLVVDDTGGLITAAVLERMGSEGSILLFNESDSPPAWGILQTMNFSDRELEPIKWLNWLEAEEEYQKPAPPVQAEPPTNPIKAAAKQRKYAAQVAELNNTRNELHLGGWDGLILATTLNPISVVARLTPYLLGSAPIVVYSPYYQVLAELLSWSKKDPNYLNDTLTESWERTYQVLPGRTHPMMTTSATGGYLWNATRVHPSQFQPESHQRFKRRKTGKAPGKEQLSSVAKDEEAVNESLEIDPEELANEGE
What is the function of this protein?
Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, tRNA(m1A58)-methyltransferase subunit TRM6, tRNA(m1A58)MTase subunit TRM6.
What is the protein family that this protein belongs to?
Belongs to the TRM6/GCD10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUCC_ECOSM
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: EXB10_ORYSJ
Sequence: MASSCLLLACVVAAAMVSAVSCGPPKVPPGPNITAAYGKQWLEARGTWYGKPKGAGPDDNGGACGYKDIDKAPFLGMNSCGNDPIFKDGKGCGSCFEVKCSKPEACSDKPVIIHITDMNTEPIAAYHFDLSGHAFGAMAKEGKDEELRKAGIIDMQFRRVRCKYPGETKVTFHVEKGSNPNYFAVLVKYVGGDGDVVKVELKEKGSEEWKPLNESWGAIWRIDTPKPLKGPFSLRVTTESDQKLVANDVIPDNWKANALYKSEIQVD
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-B10, Beta-expansin-10, OsEXPB10, OsaEXPb1.5.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: UPE37_UPEMJ
Sequence: GVGDIFRKIVSTIKNVV
What are the official names of this protein?
Uperin-3.7.
What are the subcellular locations of this protein?
Secreted.
Protein: CDD_SHEB8
Sequence: MQDRFIRSITQLPTPLADALIPMLHQNFAGHLDAQQLATLTSASKMTEAEVLLALLPIAAALAKPPISEFYVGAIAKGKSGDIYMGANLELPGEALFHSVHAEQSAISHAWLSGESQIVDIIVNASPCGHCRQFMNELVEGSKISIHLPAQESHPLAYYLPYAFGPKDLNVTSPLMAKQQTEFALDSADPMIIEGLDHAGLSYAPYTQSFAAVVLETRDGATYCGRYAENAAFNPSMLPMQMALSNLVRHNREFSDISRAVLIESSQGKISLVGATMDALHTVAAIELEHIVIDPV
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: HEMH_XYLFM
Sequence: MNHTSDTALLIVNLGTPEAPTAAAVRRYLGEFLSDRRVVSIPPLFWKPLLHMVILPIRGPRSASKYAKVWLQEGSPLSVYTRRIAEGLTQHLPDWRVAWAMRYGAPALTKALDALQAQQVRRIVILPLYPQYSTTTTASVQDVVEAWCKRTPQVQVECIQDYAEDPAWVAAVAASIRRHWQAHGRSEKLMFSFHGLPQRVANNGDPYPQRCQVSASLIAAALNLNESEWVLGYQSRFGTERWLQPYAEPTLWALAESGIRRFDLVCPGFSVDCLETLEEVALGFSETLAARGATMRYIPCLNDDPAHVQALAGLAQRALL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.