PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_NEPOL
Sequence: MIQNLQRKDSQWTPFILPDLISIQRDSFLLFLERGLATELSHVTPLTGSHFRITLCSHGYRLKRPKVSIQEAVYQATSYSAALYVNVETNQSNLGTQETQIQSVWMGDIPLMTSRGHFIINGSSRVVVNQIVRSPGIYFKEMIDQKHRRMFQASIISNRGSWVRLETDVDGMIWVRMDKAKKISILIVLEAMGLSKKTIFRSLKSPEFLFKALQQLLAKKRWQDKVYELIPQSTTDALFHLYTKLSPDKPGNTLTARRVLYEKLMDAKRYDVGLVGRVKLNKKLKLPVPEHVHTLRPVDFLAATDYLIGLEYGRGQVDDIDHLKNRRVRCAGELIQSQLRIGLNRLERTMQGRISRPGELPGMSSLMNPKPVMAALREFFGSNPLSQFMDQTNPLAELTHKRRLSSLGPGGLSQDRAGMAVREIHPSQYGRICPIETPEGPNAGLIGSMATYARLNQYGGLECPFYQVVEGKVLYEFGPIFLTAEQEDQVTVVAGDILDQRKLMVAVAEGRDPLDPAVRPTLPDRPLILRSRQEFHTGSFRDVNYVGIAPTQMISVATSLIPFLEHDDANRALMGSNMQRQAVPLLKTEAPIIGTGLEAQVAADAGGVVQSPFEGIVVYVDATRIVVSTSKSKLALSKKRKIHESNVFLQVYQRSNQGTCIHQRPIIPLHTPVIRGDLLADGSSTSGGQIALGKNLLVAYMPWEGYNFEDAILISERLIYDDLYTSLHIERYEVETQHTKLGPEEITKSIVHETDDKLPYRWLDERGIVMRGAWVEPGDVLIGKITPKEEKELTPELRLVYAIFGKRPKGFRDTSLRVPQGVRGRVVDVRMIRDEDTKVVHVYVCQQRQIQVGDKMAGRHGNKGIVSRIVPRQDMPYLQDGTPVDMVLNPLGVPSRMNVGQVFECLLGLAGQRLGQQLKVRAFDEMYGAEASRHLVYNKLHEASEVTGHHWLFDPNHPGKSRLIDGRTGDMFDQAVTIGQAYMLKLIHQVDDKIHARATGPYSLITQQPLGGRSKRGGQRLGEMEVWAFEGFGAAYTLQELLTVKSDDMQGRNEIMSAMVQGRQLPEMGTPESFKVMIRELQALCLDIGIYHRSKMTFKTEEIDLMQMR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARGB_ECO57
Sequence: MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_NITOC
Sequence: MTAPKAVVLVSGGLDSATVLAIAREQEFICHTLSFNYGQRHRVELQAAAEISRRMGAVEHKRITIDLGGFGGSALTDPSMAVPEASSGAIPITYVPARNTVFLSFALGWAEVLGAQDIFIGVNAVDYSGYPDCRPAFIKAFEHLAKLATCAGLEGRAFRIQAPLLHLSKAEIIREGMRLGIDYSRTISCYQADENGRACGVCDSCRFRKQGFWDAGVPDPTRYH
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: TATC_RICPR
Sequence: MKLYSFQEHLLEFKIRLLRIFTAFIIIFAICYYFSDYIYSFLLEPLAKLSGDTVRNIIYTGLTEAFFTYIKLSAFTAFTIIIPIIALECYLFISPGLYRHEKKIIAFILFMSPILFWCGSIFVFYFVMPKAWNFFLSFEKRDMIVPIILEARISEYLNLVIHLIIAFGIAFQLPIVIIVLNILKIVKTQTLKKKRRIAVVINFIIAGILTPPDILSQFALAIPLLLLYETSIIICNFIETPRTLNVKYQMD
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
What are the official names of this protein?
Sec-independent protein translocase protein TatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RF3_ACTP7
Sequence: MSYPQEVNKRRTFAIISHPDAGKTTITEKVLLYGNAIQTAGSVKGKGSSAHAKSDWMEMEKQRGISITTSVMQFPYNNCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEERTIKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVESVLKIRCAPITWPIGCGKLFKGVYHIAKDETYLYQSGQGSTIQEVRIVKGLSSPELDAAVGDDLANQLREELELVQGASNEFDHEAFINGELTPVFFGTALGNFGVDHFLDGLTEWAPKPQARQTDVRTVESSEEKFSGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLKHVRIGKDVVISDALTFMAGDRSHAEEAYAGDIIGLHNHGTIQIGDTFTQGEVMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPLMNNDLIVGAVGVLQFDVVVSRLKTEYNVEAIYEAVNVATARWVECCDAKKFEEFKRKNEQNLALDGGDNLTYIAPTMVNLNLAQERYPDINFFKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOST1_HUMAN
Sequence: MGECPHLVDVRLGHRSLATGPEQSDICHTGSEARWTTTWYGSLSFSRHKYKMLADLTPGVEMSCRHWARWLTPVIPALWKAEAGGLPELRSSRPAWTTW
What is the function of this protein?
May be involved in cell survival, proliferation and progression of cancer cells.
What are the official names of this protein?
Protein MOST-1.
What are the subcellular locations of this protein?
Cytoplasm. Microsome membrane. Endoplasmic reticulum membrane.
Protein: PYRB_METMJ
Sequence: MYHIISIRDFERSDLDYLLDRAQEFDTGKYRPGMLDDKLVALLFFEPSTRTRMSFATAMARLGGRSISVDSVEASSIVKGETLADTIRVVSGYADAIVLRHPKEGAARLASEFATVPVINAGDGAGQHPSQTLLDLYTIRQSMPVDGIDVGLLGDLRYGRTAHSLALALSLYGVTLHTIAPVGLEMPANIALELRERGMEVVEHPNVEEAIRELDVLYVTRIQRERFPDSASYYNVASSYRITTDLLDGVKERLMILHPLPRAGEIDPAVDRTPYARYFEQARNGVPIRMALLHEVMK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PPK5_LAXSS
Sequence: GGETSGETKGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, FXPRL-amide, LaxSp-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HTPG_PSYA2
Sequence: MSEQNPTDSKNPELKKHTFEAEVAQLLHLVTHSLYSNSDIFVRELVSNASDACDKLRFEATNDDSLYEDDGELRIRIAVDEDAKTITFTDNGIGMNEADAIENLGTIAKSGTKAFLDKLSDSQKQDGQLIGQFGVGFYSGFIVADTISVETRKAGDAAENGVRWVSDGTGSFTVENISKTERGSSITLHLKEQYSEGEDGYLDRSKIKRLVNKYSDHISLPIQMRKEIWQEDEVEEGDDTPANGQMVLTDEWETINKASALWTRTASDVEDDEYVDFYKNITYDMDAPLTWTHNRVEGRVQYTQLLYIPKKAPVDLYTREQQHGLKLYVKRVFIMDDAEQLLPMYLRFVKGVIDSADLPLNVSREILQESRDVKSIRDGNARRILTLLASLANSEDADKQEKFAQFYAEFGDVIKEGVGEDMGNQERIAKLLRYATSTQDGEMTSFEDYKARMKDGQKAIYYLTADNLAAAKNSPQLELFKKKGIEVILMTSRVDEWAMNFLTSFDETPLQNIAKGAVDLGDLQDEAEKAEAEKAQETMKPVVDKLKAALGDRAKDVKVSTRLVDSPACLVVGEGELSPQMIQMLKQMGQDVPESKPTLEVNPDHPLIKKLESSEQSAEDFDKLAQVIFDQALLADGGQLEDPAAYLRRVNELLMK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK1_TARBI
Sequence: QGLIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, Tarbi-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP25_NEUCR
Sequence: MSATPAVLRASACSACRFSALRLFVSSFASPRAPLPVARTRVLSPTAPYSTFRPSPRLLASPSSEEHAEPAAQEQPNKTEDAQAEASTEANNEGGADVPWYLQVDAPTHPTLVHEPPPLPDIPEGSPKLMEPLVKFVSDELGMDDLKLLDLREIDPPPALGPEVLMLFGTARSERHLHVSADRLVRWLRNRGVTAKADGLLGRNELKTKLRRKARKAKLLGTTGLPSGADDGITTGWICVNLGTLGWSDMEMEFKDEKGVTSGFGVPQSGTTLVVQLMTETRREELALEKLWSGILRRSLERQDKIAGKLPEASFTTSPDTVSGQSFSPSPIRSSGRNRKRPDRLYFSTSARQHAAAVDVSQTDLATAMAGWEYSNASPSTIDNLLAQDTDSKVQLLIQMQEYLSSLPRDQALSAVSLCEDGSPSTFMRLFNRAIENLPSAQAWEARLWVEKAARALQHPDHDLARLGDLIQEMKLSGAANVSREKFVDLLRMIFAIPETTDAGVRQQASLSMDVIDMLFSRGEKVIEYDVVVAVIESLLQTRARPPEARRLLSQFEDLLSEAQMDCPTEDEIIRLLDVYANHRAWDKFWNVWRVFPRHCERRTERMYTKVYERIAAEDHQGMATDALRWCVEEMWHEQPPVRVTAAMLKALEACIRIADPEAESLAKDIDDRISDAQYMDREFVRLWLTLHGSAAWGA
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GCST_BURPS
Sequence: MTVLKTTPLHAAHRALNARMVDFGGWDMPVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHAIANNVAKLQTPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTAEKDIAWFNQLNEQGGFGLTIAPRRDFAIVAAQGPNARAKVWDTVPCARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEIIVPATHVEALWNALAERGVRPCGLGARDTLRLEAGMNLYGQDMDESVSPLDAGLAWTVDLSAPRAFVGRDALEAHGSRAAFVGLILQKENGRAGGVLRAHQKVATPHGEGEITSGTFSPSMQESIAFARVPKDVAIGDTVHVQIRDKQLPARVVKLPFVRNGKVLAA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: MURI_BRUSI
Sequence: MKKAPAGSFPAKPTIAPERPILVFDSGIGGLTVLREARVVMPDRRFVYIADDAGFPYGNWEEEALKRRIIELFGEFIANYDPEIAVIACNTASTLVLEDLRRAYPSVPFVGMVPAIKPAAERTSSGLVSVLATPGTVKRAYTRDLIQSFASRCHVRLVGADGLAAIAEAHIRGESFDEALVMAQIAPCFIEKDGKRTDIVVLACTHYPFLVNVLRRLAPWPVDWLDPAEAIARRMKSLLPARSDDDEFHSQDDLAFFTSRKPDYAIRRLMQGFGLRF
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PIM1_BOVIN
Sequence: MLLSKINSLAHLRAAPCSDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHDCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIVRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK
What is the function of this protein?
Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis.  Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5).  Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity.  The stabilization of MYC exerted by PIM1 might explain partly the strong synergism between these two oncogenes in tumorigenesis.  Mediates survival signaling through phosphorylation of BAD, which induces release of the anti-apoptotic protein Bcl-X(L)/BCL2L1.  Phosphorylation of MAP3K5, another proapoptotic protein, by PIM1, significantly decreases MAP3K5 kinase activity and inhibits MAP3K5-mediated phosphorylation of JNK and JNK/p38MAPK subsequently reducing caspase-3 activation and cell apoptosis.  Stimulates cell cycle progression at the G1-S and G2-M transitions by phosphorylation of CDC25A and CDC25C.  Phosphorylation of CDKN1A, a regulator of cell cycle progression at G1, results in the relocation of CDKN1A to the cytoplasm and enhanced CDKN1A protein stability.  Promotes cell cycle progression and tumorigenesis by down-regulating expression of a regulator of cell cycle progression, CDKN1B, at both transcriptional and post-translational levels.  Phosphorylation of CDKN1B, induces 14-3-3 protein binding, nuclear export and proteasome-dependent degradation.  May affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3.  Acts also as a regulator of homing and migration of bone marrow cells involving functional interaction with the CXCL12-CXCR4 signaling axis.  Also phosphorylates and activates the ATP-binding cassette transporter ABCG2, allowing resistance to drugs through their excretion from cells.  Promotes brown adipocyte differentiation (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase pim-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DPSA_SYNP6
Sequence: MTNTGLVQSFSQIEPNVLGLETSVTSQICEGLNRALASFQVLYLQYQKHHFTVQGAEFYSLHEFFEDSYGSVKDHVHDLGERLNGLGGVPVAHPLKLAELTCFAIEEDGVFNCRTMLEHDLAAEQAILSLLRRLTAQVESLGDRATRYLLEGILLKTEERAYHIAHFLAPDSLKLA
What is the function of this protein?
Involved in protection of chromosomal DNA from damage under nutrient-limited and oxidative stress conditions.  Binds heme (By similarity).
What are the official names of this protein?
Nutrient stress-induced DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
Protein: LOR16_ARATH
Sequence: MGARSSQTVDPVLSRRYSSESETVLVVRRRPPMVNGGGFVVSNSKQVVVFRVDGCGVLGTKGKLLLRNGDGNDLLLIRKMGGIVQALNMVHNKWEGFGYDNEGTERLVFTLKDPKDSCLVQNSSIKILVHGKPPKISSTRNNYVEIKGSFAERACNIMDSDGKAIAKVRIEKEMEEMVGNKKDLYHVIVKPNVDQSFIVGLIAILDYIHGESTIC
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 16.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: OADG1_VIBCH
Sequence: MTHIGSLLLDAATLMVTGMAVVFLFLTLLVYLVQFMSRVIPQEVPEAAATPKKSQKVQPVTDSVSPQVVAAIAAAVHQHRSATAKQ
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
What are the official names of this protein?
Probable oxaloacetate decarboxylase gamma chain 1.
What is the protein family that this protein belongs to?
Belongs to the OadG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RAB6A_PONAB
Sequence: MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC
What is the function of this protein?
Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).  Has a low GTPase activity.  Involved in COPI-independent retrograde transport from the Golgi to the ER.  Recruits VPS13B isoform 2 to the Golgi membrane.  Plays a role in neuron projection development.
What are the official names of this protein?
Ras-related protein Rab-6A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid-anchor. Note=BICD2 facilitates its targeting to Golgi apparatus membrane.
Protein: YBRI_CAEEL
Sequence: MSEELLQKFLTSIEQEDGIAEIGKKKKNKSAARRDNVKTILHAASKGQVQLSAEESYIVQKPSTSKGSDYIDDRLASQGFSLIDQARSFKPKDLKKRNLKYMKFQEGRRIDKKKGRILVQAHMQTKQDLKSLRKEKKAIIGVKEPRRLLPGQKKKQKDKSVFSDADFAQVAHVAKRINSMADHSFL
What are the official names of this protein?
Uncharacterized protein C26F1.3.
Protein: RL9_BUCAI
Sequence: MEVILLSKIKKLGDSGAVINVKSGYARNFLIPKGKAILANKKNIESFEAQRIALEKEKINELLIAQSRAEKLKKINSITILSKVGKEGKIFGSVGVRNIIKEIILLGIKINKKEIRLPNGLLRQVGEHIVVFQPHSKVSINFIVKIIAKN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RL10_ECO27
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RR4_STAPU
Sequence: MSRYRGPRLKIIRRLNTPLPGLTSSPIVNSTVNTKSQRKDKSEYRIRLEEKQKLRFHYGITERQLLRYVRLARRAKGSTGQVLLQLLEMRLDNIIFRLGMAPTIPAARQLVNHGHVLVNERVVDIPSFRCKPQENISIRDRARSRALVDKNLNNSQESKKLSPSRDFLSKVPTHLRINTKNYKASVNQVVNRNSIGVKVNELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS21_PROM0
Sequence: MTQVTVGENEGIESALRRFKRQVSKSGIFADLKRLRHHETPVEKYKRKLQQRRKARRR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: MTURN_BOVIN
Sequence: MDFQQLADVAEKWCSNTPFELIATEETERRMDFYADPGVSFYVLCPDNGCGDNFHVWSESEDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ
What is the function of this protein?
Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression (By similarity).  Represses NF-kappa-B transcriptional activity by inhibiting phosphorylation of RELA at 'Ser- 536' (By similarity).  May be involved in early neuronal development (By similarity).
What are the official names of this protein?
Maturin, Maturin neural progenitor differentiation regulator protein homolog.
What is the protein family that this protein belongs to?
Belongs to the MTURN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMD2_DICDI
Sequence: MIIELDNTHKQDLSSLRSLSAEIISEFCKIALEFIKKGSNKKLYMGASQKLNIAADKIESLVDSITYLFSECTRFMLNENDFNDTLAPIKLSDEVIEILRESYFDNRKDIRNTLQEFYPHLDHYQNLEWRLDTQIANRSLGSSINPIYLLKLITKCGSDNPIEHLLQTDPNNLKHLCNELESALNEIRTYENRLIIRNIK
What are the official names of this protein?
COMM domain-containing protein 2.
Protein: COBT_MYCTA
Sequence: MIGFAPVSTPDAAAEAAARARQDSLTKPRGALGSLEDLSVWVASCQQRCPPRQFERARVVVFAGDHGVARSGVSAYPPEVTAQMVANIDAGGAAINALADVAGATVRVADLAVDADPLSERIGAHKVRRGSGNIATEDALTNDETAAAITAGQQIADEEVDAGADLLIAGDMGIGNTTAAAVLVAALTDAEPVAVVGFGTGIDDAGWARKTAAVRDALFRVRPVLPDPVGLLRCAGGADLAAIAGFCAQAAVRRTPLLLDGVAVTAAALVAERLAPGAHRWWQAGHRSSEPGHGLALAALGLDPIVDLHMRLGEGTGAAVALMVLRAAVAALSSMATFTEAGVSTRSVDGVDRTAPPAVSP
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: IF5A_METBU
Sequence: MKQQVEVKELKEGKYVLADDEPCVIKSIQKSKPGKHGSAKARIEAIGIFDGQKRSIISSVSAKTYVPIVERKSAQVLSISSNIAQLMDMETYTTFELTIPEDYKDRVTEGKDITYIEAMGKMKIDLR
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMC_ECOLI
Sequence: MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEAAPLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGDTASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGRYQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAANAAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNMAVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDALVAVFQAAFSK
What is the function of this protein?
Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD.  Efficient substrate folding and insertion into the outer membrane requires all 5 subunits (PubMed:20378773, PubMed:21823654, PubMed:27686148).  A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly complete Bam complexes show there is considerable movement of all 5 proteins (PubMed:27686148, PubMed:26900875, PubMed:26901871, PubMed:26744406).
What are the official names of this protein?
Outer membrane protein assembly factor BamC.
What is the protein family that this protein belongs to?
Belongs to the BamC family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ACCA_BRUA4
Sequence: MYNYLDFEKPVADLEGQILELKKLAQEQGSVEMSDEIRRLEKRSADALKDIYRKLTPWQKTQIARHPDRPHCLEYIDRLFTEFTPLAGDRKFANDEALQTGFGRFNGQAVAIIGQEKGSDTKTRLKHNFGSARPEGYRKAVRIMEMADRFQLPLITFVDTAGAYPGVSAEERGQAEAIARSTAECLRLRVPVISIIIGEGGSGGAIAIAVANRVYMLEHSIYSVISPEGAASILWHDSTRAKDAASSMRITAQDLFDLKVIDGVIPEPMGGAHRGKEAVIDAAGDIITASLRSMKDIDGETLKQERRQKFLEIGRNI
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_VESOH
Sequence: MLINFTKMHGLGNDFMVVDNLAGDITFNAKKITNLANRAFGIGFDQLLVVETSNIRGVDFRYVIYNSNGSEVEQCGNGARCFARFVNYKNLTHSNPITVKTRSNIISLHLNDDNTVCVDMGKPSFNPADIPLLVPQQSEYYQIEGFDLGAISIGNPHCVMLVKDVNTIDVNTIALKIQQSELLPNQANIGFMQILNTHEINLRVYERGSEETLACGSGACAAVAYGVEQGLLKKNVVVHLSGGDALIEYTQGGHIFLSGPAQFVFEGQVEI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_OPITP
Sequence: MLTEKQEAILDYIRSVQAQRGVPPSTREIQRHFGYESQNAAMNHLRALARKGQLHQVDGATWGLKVSEVQGHFELPIYGTIPAGVPSMQEQQPKETITFDPAVFRLRRPERLWGLEVHGDSMIDAHILDGDIAVLERREAKPGDIVAALVDETTTTLKRLAYVKGKPVLKPENARYALIVPKDRLEIQGVFVGLIGRAKR
What is the function of this protein?
Binds a consensus sequence 5'-TGTTC-N(4)-GAACA-3'; some genes have a tandem consensus sequence and their binding is cooperative (PubMed:27489856).  Binds to the promoters of a number of genes, including lexA and splB (PubMed:27489856).  Represses a number of genes involved in the response to DNA damage (SOS response).
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.