PharMolix/UniProtQA huggingface dataset:
Protein: ACCD_CUSRE
Sequence: MERREGGRDNSSCSNVNQLFGVKDSESLLYDDVFIVRDRNGDSYFAYWDIEKNTFLSEPFYSYRSRNSSYLPKIKAFMSEDRSQIHEVKNGFRSEDHSKINKINGVENLFHNYNMNVLTDDYNFKMGMNGFHRPQSKIHINRFIDSYLQSQICIATTPGSGSDNDSYIHGSRVYGESESYTRSEGRSSSIRTRTKGVELTLRERPGILDRTKKYMYLWLQCDNCYGLNYKKVLKSKMTICEQCGYHLQMSSSDRIELLIDPGTWDPMDEDMVSRDPIKFDSGGGEAYKDRLYFYQRKTGLTEAVQTGIGQLNGIPVAIGVMDFKFMGGSMGSVVGEKITRLIEHATNKFLPLIIVSASGGARMQEGSLSLMQMAKISSALYDYQSNKRLVYVSILTSPTAGGVTASFGMLGDIIIVEPRAYVAFAGKRVIEQTLNQTIPNDSQEAEFLFHKGLFDLIIPRHLLKSVISELFTLHDLFPLNQNSNQYSQYRALLNPIF
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid.
Protein: UGPC2_RHIEC
Sequence: MAPISIRDVKKSYGKHPVVHGVDLEIQSGEFIVILGPSGCGKSTLLRMIAGLEEITGGEIAIDGRVVNQMEPRERGCAMVFQNYALYPHMTVAENIGYALKVAGVAKTERSRRIAEVAKALSLEPFLDRRPAALSGGQRQRVAMGRAMIREPKVFLFDEPLSNLDAKLRIAMRAEIRRLHRRLGATSIFVTHDQTEAMTLADRLVVMNGGRVEQVGTPEEVYHHPVSRFVAGFVGTPAMNLLEGTINDEGVFVYDQSRKIALPRERAAALKGKRVVLGMRAEAARLVVPDAPGALVATADFIEELGASRVVHADFDGLPFAVALTEAVSVKSGDPIGIAIDHNAIHLYAADTGRLIENSAMSGAGAVHA
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YXAF_BACSU
Sequence: MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYHFFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPVEAIQLFIKKTASQFDNTESIKGIPVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMIEGGIMLSLTNKDKTPLLLIAEQIPVLVRKKG
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YxaF.
Protein: LPQB_MYCVP
Sequence: MRRIAALWLCALMVFAVGCAGVPSSSSPQAIGTVDRPAPPSLPKPTPAMDPDVLLREFLKATADPANRHLAARQFLTESASSTWDDAGSALLIDNVVFVETRAPERVSVTMRADILGSLSDMGVFETGAGALPDPGPIELVKTPDGWRIDRLPNGVFLDWQQFQATYKRHTLYFADPTGKTVVPDPRYVAVSEPDQLATELVSKLVAGPRPEMDKTVRNLLGSPLRLRGPVTRADGGKTGVGRGYGGARVDLENLSTTDPHSRQLLAAQLIWTLSRSGINGPYVLNADGAALDDRFAEGWDTADVAATDPGAADGAAAGLHALVGGSLVRLDGQRAPRVSGQFGQMPGQTAASLSRTGQEVASIVTLRPGAPDMASSLWVGPLGGNASQVLDGRSLTRPSWSLDDAIWTVVDGNNVVRVIQDASGQPARIPVDASAVVTRFPGAIAELQLSRDGTRAAMVIEGKIVLAGVEQTAGGNYALTYPRRLGYGLGETAVSLSWRTGDDIVVTRTVAQSPVSYVNLDGVNSDGPSRNLLMPVKTVAANPSAVYVADGRGILQLSGSAAEDPGWSEVRPLMSAGALPVLPG
What are the official names of this protein?
Lipoprotein LpqB.
What is the protein family that this protein belongs to?
Belongs to the LpqB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GCSH_SALCH
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYTGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: PBX1_XENTR
Sequence: MDDQPRLMHSHPGVGMAGHPSLSQHMQDGTGANEGEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPADPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGAGADNSAEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCAITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVNATNVSVHGSQANSPSTPSSAGGYPSPCYQSDRRIQ
What is the function of this protein?
Acts as a transcriptional activator in complex with isoform 2 of meis1, to induce posterior neural and neural crest gene expression, and thereby specify hindbrain and neural crest cell fate.  Binds to a highly conserved region in the promoter of the neural crest gene zic3.  Required for the nuclear transport or retention of meis1 (By similarity).
What are the official names of this protein?
Pre-B-cell leukemia transcription factor 1, Homeobox protein pbx1.
What is the protein family that this protein belongs to?
Belongs to the TALE/PBX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SODC_SAPAP
Sequence: MAMKAVCVLKGDGPVQGTINFEQKESNGPVKVWGSITGLAEGLHGFHVHQFGDNTQGCTSAGPHFNPLSRKHGGPEDEERHVGDLGNVTAGKDGVAKVSIEDSVISLSGDHSIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HIS6_LACP3
Sequence: MLTKRIIPCLDVDHGRVKKGINFVQLKDVGDPVAIAKAYQEQGADELVFLDITATNEARGTLVQTVEAVANQVFMPLTVGGGIQSVADMHALLRAGADKVSLNSAAVADPSLLTAGAEKFGRQAIVAAIDTRWQADQNRYQVTVNGGRTPVDLDAITWAKQAVAAGAGELLVTSMDADGTESGFDLRLYQQLTAAVQVPIIASGGAGSTADFVQLFTQTTVSAGLAASIFHFGELTVPQVKTALKQAKVAVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC5A3_MOUSE
Sequence: MRAVLEAADIAVVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMVKIGGFEEVKRRYMLASPDVASILLKYNLSNTNACMVHPKANALKMLRDPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRIVFADEIACINPEHCMQVCGSRAGCSNIAYPRLVMTLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAFTYRAPECDQPDNRPGFIKDIHYMYVATALFWITGLITVIVSLLTPPPTKDQIRTTTFWSKKTLVTKESCSQKDEPYKMQEKSILQCSENSEVISHTIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASMGHSEAETPVDAYSNGQAALMGEREREKETENRSRYWKFIDWFCGFKSKSLSKRSLRDLMDEEAVCLQMLEETPQVKVILNIGLFAVCSLGIFMFVYFSL
What is the function of this protein?
(Microbial infection) Functions as a retroviral receptor for M813 murine leukemia virus (MuLV) entry.
What are the official names of this protein?
Sodium/myo-inositol cotransporter, Na(+)/myo-inositol cotransporter, Sodium/myo-inositol transporter 1, SMIT1, Solute carrier family 5 member 3.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AROK_ACTP2
Sequence: MAEKRNIFLIGPMGAGKSTIGRQLAQMLGMEFIDSDAVIEERAGADIDWIFDLEGETGFRKREERIINELTQNQGVVLSTGGGSVLSKENRNVLSARGIVIYLETTVDKQFERTQRDKKRPLLQTENPRETLEALAKVRNPLYEEIADITLQTDEQSAKLVATHIIELIDNLQ
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_SHEPC
Sequence: MSKITSSTLLKYKQEGRKFTALTAYDASFAGAFDSEGVDVLLVGDSLGMVLQGHDDTLPVTTAEIAYHTRCVRRGIERALLIADMPFMSYATPEQAMINATELMQAGANMVKVEGGHWLLETVTKLTERGIPVCAHLGLTPQSVHVFGGFKVQGRDAENAQRILDEAKALEAAGAQLLVVECIPAPLATAITQALTIPVIGIGAGASTDGQILVMHDVLGISSGYIPRFSKNYLKQTGEIRSAVRAYIEEVAAGTFPSAEHTFS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALF1_OCEIH
Sequence: MNQKQLEQMKTSKGFIAALDQSGGSTPKALAAYGIPEDSYNNEDEMFDLVHEMRTRIITSKAFDSDSIIGAILFEQTMDREIEGMYTGDYLAEKKGIVPFLKVDKGLAEETNGVQLMKPIDNLDETLRRANERNIFGTKMRSVIKQANPKAIKEVVDQQFDIGKKIIAAGLVPIIEPEVDIHSPEKEKCEDLLKAEIINHLNQLSEDENVMLKLTIPTKKNLYKELIDHPRVVRVVALSGGYSTDVANEKLKENNGLIASFSRALSQDLNADQSDEDFNLALEKAVKSIYDASV
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: PHNX_SALTI
Sequence: MNRIHAVILDWAGTTVDFGSFAPTQIFVEAFRQAFDVEITLAEARVPMGLGKWQHIEALGKLPTVDARWQAKFGRAMSAADIDAIYAAFMPLQIAKVVDFSSPIAGVIDTIATLRAEGIKIGSCSGYPRAVMERLVPAAAEHGYRPDHWVATDDLVAGGRPGPWMALQNVIALGIDAVAHCVKVDDAAPGISEGLNAGMWTVGLAVSGNEFGATWDAYQTMSKEDVAVRREHAASKLYAAGAHYVVDSLADLPEVIAHINARLAQGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: ORC5_ORYSJ
Sequence: MSQPVTPRRTTRSSASASPSPAPASPTSPPKSRPKPSPRRQLLAAAAAPPKEDGSSADALLAELPGRRAQAMDILRLLAPAPALPLMLHGGAATGKTRALLLALRYLRPSQRLVYAALRSLPSPRALFASLLSQLSATPFSTSSRHRVPDKPSDFVAALRDALNGIVSQGEVVYLVFDNLEVVRSWDKGGQLLPLLLRLHDLLQLPQVVLVYVSSATPDAYYSMTGSVEPNYVYFPDYTVDEVRDILMHDHPNPKLYSSFLSVALKPLFRVTRRVDELSAVLEPLFRRYCEPLGDLKAVPDEGMKRRLFEHVQSHLAVALNETFNVPMRASMDEIKDGGSAGKGSAKRQFAGKDGLSSELEFHMSVSAKYLLLSAFLASRNPATLDAALFDSTGGLDNRKRKRKSSQASMHMKDTIVEEMLMKGPGTFPLERLLAIFQCITSVSEDILDEIDCPGNMASESGTTGLMSDVLLQLSTLCNSNFLSKSRSCPLEGSARYRSNIDEDLALKVARSVNFPLSKYMYRR
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
What are the official names of this protein?
Origin of replication complex subunit 1, OsORC1.
What is the protein family that this protein belongs to?
Belongs to the ORC5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HCAR2_RAT
Sequence: MSKQNHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLTDNYVQNWDWRFGSIPCRVMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHFLNKISNRTAAIISCFLWGITIGLTVHLLYTDMMTRNGDANLCSSFSICYTFRWHDAMFLLEFFLPLGIILFCSGRIIWSLRQRQMDRHVKIKRAINFIMVVAIVFVICFLPSVAVRIRIFWLLYKHNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPNFFSTCINRCLRRKTLGEPDNNRSTSVELTGDPSTIRSIPGALMTDPSEPGSPPYLASTSR
What is the function of this protein?
Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase.  This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.  Mediates nicotinic acid-induced apoptosis in mature neutrophils.  Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.  The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide.
What are the official names of this protein?
Hydroxycarboxylic acid receptor 2, G-protein coupled receptor 109, G-protein coupled receptor 109A, G-protein coupled receptor HM74, Niacin receptor 1, Nicotinic acid receptor, Protein PUMA-G.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUD_TOLAT
Sequence: MQEFKQHTGLAVPLDSANVDTDQIIPKQFLQRVSKLGFGQNLFHDWRFLDEAGTQPNPEFVLNFPRYKGASILLARENFGNGSSREHAPWALADYGLKAVIAPSFADIFYGNSLNNGLLVVRLKDDEVDALFKLVEANEGQNITVDLEAKEVRAADYCFKFEIDDFRRYCIMNGLDNIGLTLQHADAIDAYEAKQPVWL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: TRM1_HALLT
Sequence: MDIEEGGLTVSVPEARDGASEGTGGGVFFNPTQELNRDVTVAVLRAYRDREPRASSYLDAMAASGIRGVRAAAEGYDTTCADVDPDAVELAAENLAANDLDGETVHRDVNALLYENVFDVVDLDPYGTPIPFADAALANARNLVCVTATDTAPLCGAHLNSGIRKYGAVPRNTDYHPEMGLRTLISALVRTAARYDKAARPIVSHVSRHYARTYLELESGAQVADDCIDELGYIDNCEDCLWRDPTHGLIADPVDTCPVCGSDRVLTAGPLWLGPVADPDFARAVRERVTDDMGEAKRARKLLGTVARELDTPTHYDQHRLYKAWGEPAIGMDEFVDRLRGAGYEASRAHYRGTAVKSTASIPEMRDAILGNEGDADGDAD
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: YE1A_CAEEL
Sequence: MAKIFCMLVVLLVSSSFCSAKDLKRSKRQMQVYYMCNGGVSQYPCNSNNNCNNNNCNFNNYGNQVILPSSFYNPNMNCNSNCNNLNCNQYSGSWLNGQYVAYNMGSNAYSPCASSCCSNNNNNYNPYINNNYNGNYNPYGTSNGGYNAYGTIPVNVNVPSSSTNTNVNQYLPYGAQQFTGTYQNGQFFCGATEPSGGVCRNNGVCPSGHSCVAGNVCCRCPVGSSAGNCILQSDCSAGYECMGTGYCCPSQVLSTTKLGPCVDGACPLPGYTCGVGDLCYPDSYFL
What are the official names of this protein?
Uncharacterized protein C35A5.10.
Protein: Y1279_MYCTO
Sequence: MDTQSDYVVVGTGSAGAVVASRLSTDPATTVVALEAGPRDKNRFIGVPAAFSKLFRSEIDWDYLTEPQPELDGREIYWPRGKVLGGSSSMNAMMWVRGFASDYDEWAARAGPRWSYADVLGYFRRIENVTAAWHFVSGDDSGVTGPLHISRQRSPRSVTAAWLAAARECGFAAARPNSPRPEGFCETVVTQRRGARFSTADAYLKPAMRRKNLRVLTGATATRVVIDGDRAVGVEYQSDGQTRIVYARREVVLCAGAVNSPQLLMLSGIGDRDHLAEHDIDTVYHAPEVGCNLLDHLVTVLGFDVEKDSLFAAEKPGQLISYLLRRRGMLTSNVGEAYGFVRSRPELKLPDLELIFAPAPFYDEALVPPAGHGVVFGPILVAPQSRGQITLRSADPHAKPVIEPRYLSDLGGVDRAAMMAGLRICARIAQARPLRDLLGSIARPRNSTELDEATLELALATCSHTLYHPMGTCRMGSDEASVVDPQLRVRGVDGLRVADASVMPSTVRGHTHAPSVLIGEKAADLIRS
What are the official names of this protein?
Uncharacterized GMC-type oxidoreductase MT1316.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: CALM_LILLO
Sequence: MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: Y3637_SACD2
Sequence: MATLDSNDKHDNHAPEAAGEFVSLRDHFLIAMPGLQDPIFSRSLTYICDHTAQGAMGIVVNQPMNLTLGDIFEQLELQDKAQQAGRAVLAGGPVNTERGFVLHRDSGAWESTMHIAPDVNLTASRDIVHAIANNTGPKSSLFALGYAGWSAGQLEEEISANSWLTIPADSSIIFDIPVEDRWAAAARQLGIDIHLMSATAGHA
What are the official names of this protein?
UPF0301 protein Sde_3637.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: LYSY_THERP
Sequence: MVVSVAILGGSGYTGGELLRLLLSHPEVEVKQVTSRSRAGKFVHTVHPNLRKRTALKFVPPEALEPVDLLFACLPHGETAPIVDRLLELAPIVIDLSADFRLRDPAAYEQWYHWTHPRPDLLAQAVYGLPELHREEIRNARYIACPGCNSTTVILGLAPLFRAGLIDLDLPVTVECKVGSSGAGGEAGPASHHPERSGVIRPFKPGGHRHTAEVLQELTVCGRTPSLGLSVTSVEAVRGILATAHLFPKQPLTDRDLWQVYRAAYGQEPFIRLVKEASGIHRYPEPKILAGSNYCDIGWELDELPGGRQRLVVMSAIDNLMKGAAGQAVQAMNIRLGFPETLGLEFPGLHPL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.
What are the official names of this protein?
Putative [LysW]-L-2-aminoadipate 6-phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_JANSC
Sequence: MSTTSRTLITSAIPYINGIKHLGNLVGSQLPADLYARYLRARGQEVLFLCATDEHGTPAELAAAKAGKPVAEYCADMHAVQAEIARGFRLSFDHFGRSSSPQNHALTQHFAGKLADAGLIAEVEEKQVYSHADGRFLPDRYIEGTCPNCGYDKARGDQCENCTKQLDPTDLINPRSAISGSTDLEVRETKHLYLRQSQLRGQLSDWISSKTDWPILTTSIAKKWLNDGDGLQDRGITRDLDWGVPVKRGDADWPGMEGKVFYVWFDAPIEYIACAAEAVEEGSISDWERWWRVDKGADDVRYVQFMGKDNVPFHTLSFPATILGSGEPWKLVDYIKSFNYLNYDGGQFSTSQGRGVFMDQALEILPSDYWRWWLLSHAPETSDAEFTWEAFQQDVNKDLADVLGNFVSRITKFCRSKFGEVVPEGGDYGPQETALIADLDKRLAAYQTHMDAIDIRKAAAELRAIWVAGNEYLQSAAPWTAFKTDPDRAAAITRFALNLIPFYAGLSAPFIPDAAQAMAEGMHTNLTWPKDARLTTLPAGHAFTVPDVLFAKIADEQREDWAARFSGVRD
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_STAAW
Sequence: MLDNKDIATPSRTRALLDKYGFNFKKSLGQNFLIDVNIINNIIDASDIDAQTGVIEIGPGMGSLTEQLARHAKRVLAFEIDQRLIPVLNDTLSPYDNVTVINEDILKANIKEAVENHLQDCEKIMVVANLPYYITTPILLNLMQQDIPIDGYVVMMQKEVGERLNAEVGSKAYGSLSIVVQYYTETSKVLTVPKSVFMPPPNVDSIVVKLMQRTEPLVTVDNEEAFFKLAKAAFAQRRKTINNNYQNYFKDGKQHKEVILQWLEQAGIDPRRRGETLSIQDFAKLYEEKKKFPQLEN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPF1L_HUMAN
Sequence: MVGGGWKRRPGAGAGPQCEKTVDVKKSKFCEADVSSDLRKEVENHYTLSLPEDFYHFWKFCEELDSEKPADPLSASLGLQLVDPYNILAGKHKMKKKSTVPNFNLHWRFYYDPPEFQTIIIRDKLSATWGISDRDSPDELPVYVGINEAKKNCIIVPNGDNVFAAVKLYLMKKLKEVTDKKKTNLFKNVDEKLTETARELGYSLEQRTMKMKQRDKKVVTKTFHGTGLVPPVDKNVVGYRELPETDADLKRICKTIVEAASDDERRKAFAPIQEMMTFVQFANDECDYGMGLELGMDLFCYGSHYFHKVAGQLLPLAYNLLKRNLFAEIMKDHLANRRKENIDQFAA
What are the official names of this protein?
Putative histone PARylation factor 1-like.
What is the protein family that this protein belongs to?
Belongs to the HPF1 family.
Protein: LHB2_RHOAC
Sequence: MADKPLTADQAEELHKYVIDGARAFVAIAAFAHVLAYSLTPWLH
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800/820 beta-1 chain, Antenna pigment protein beta-1 chain.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: SIR2_MOUSE
Sequence: MAEPDPSDPLETQAGKVQEAQDSDSDTEGGATGGEAEMDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRKVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCRKEYTMGWMKEKIFSEATPRCEQCQSVVKPDIVFFGENLPSRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQAPNPSTTISPGKSPPPAKEAARTKEKEEQQ
What is the function of this protein?
Deacetylates alpha-tubulin.
What are the official names of this protein?
NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein defatty-acylase sirtuin-2, Regulatory protein SIR2 homolog 2, SIR2-like protein 2, mSIR2L2.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Perikaryon. Cytoplasm, cytoskeleton. Cell projection. Cell projection, growth cone. Myelin membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Chromosome. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes in the cytoplasm during most of the cell cycle except in the G2/M transition and during mitosis, where it is localized in association with chromatin and induces deacetylation of histone at 'Lys-16' (H4K16ac). Colocalizes with KMT5A at mitotic foci. Colocalizes with CDK1 at centrosome during prophase and splindle fibers during metaphase. Colocalizes with Aurora kinase AURKA at centrosome during early prophase and in the centrioles and growing mitotic spindle throughout metaphase. Colocalizes with Aurora kinase AURKB during cytokinesis with the midbody. Colocalizes with microtubules (By similarity). Deacetylates FOXO3 in the cytoplasm (PubMed:17521387). Colocalizes with PLP1 in internodal regions of myelin sheat, at paranodal axoglial junction and Schmidt-Lanterman incisures (PubMed:16933150). Colocalizes with CDK5R1 in the perikaryon, neurites and growth cone of hippocampal neurons (PubMed:16933150). Colocalizes with alpha-tubulin in neuronal growth cone (PubMed:18332217). Localizes in the cytoplasm and nucleus of germinal vesicle (GV) stage oocytes (PubMed:24334550). Colocalizes with alpha- tubulin on the meiotic spindle as the oocytes enter into metaphase, and also during meiotic anaphase and telophase, especially with the midbody (PubMed:24334550).
Protein: ARCA_SALTY
Sequence: MEKHFVGSEIGQLRSVMLHRPNLSLKRLTPSNCQELLFDDVLSVERAGEEHDIFANTLRQQGIEVLLLTDLLTQTLDVADAKAWLLDTQISDYRLGPTFAADIRAWLADMPHRELARHLSGGLTYGEIPASIKNMVVDTHDINDFIMKPLPNHLFTRDTSCWIYNGVSINPMAKPARQRETNNLRAIYRWHPQFAGGDFIKYFGDEDINYDHATLEGGDVLVIGRGAVLIGMSERTTPQGVEFLAQALFKHRQAERVIAVELPKHRSCMHLDTVMTHIDIDTFSVYPEVVRPDVQCWTLTPDGRGGLKRTQESTLVHALETALGIDQVRLITTGGDAFEAEREQWNDANNVLTLRPGVVVGYERNIWTNEKYDKAGITVLPIPGDELGRGRGGARCMSCPLERDGI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.