PharMolix/UniProtQA huggingface dataset:
Protein: NANE_HAEDU
Sequence: MSKLSHSEVLIMIQGGLVVSCQPVDDGPMDQPAIVAAMAQAAIVGGAVGVRIEGVQNLKATRPMVTAPIIAIVKRDLPESAVRITPFLADIDQLAAAGADIIAVDGTDRERPVAVVAALERIHAQGCLAMADCSTLAEGLYCQQLGFDIIGSTMSGYTGGELPVEPDYQLVKDLKSAGCYVMAEGRYNSPALAKSAMQMGADCVTVGSALTRLEHMVSWFAVAVQSAKE
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: MNMA_RICM5
Sequence: MINLGDKQSTIVVAMSGGVDSSAVAAMLHEQGHNVIGITLQLYDHGMAVGKKNACCAGQDIYDAKMVANKLGIPHYVLDYESKFKESVIDNFVDSYLQGETPLPCVRCNKSVKFRDLIKTARELGADKLATGHYVRKINGDNGAELYTGLDPAKDQSYFLFTTTKEQLEYLRFPLGGLTKDETRKLASKFGLEVADKPDSQDICFVPDGNYKSVINKIRPNSSESGKIIHVNGFKLGEHSGIINYTIGQRRGLGIAYNEPLYVVKIDPKDNIVYVGPESALNVQEFIIRDVNWLADEIKDNEKLEVAVKIRSTRPPRLAEISKLGDDKMKVKFLCAEKAVAPGQACVIYAGERVLGGGWITREIR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMN_PARDP
Sequence: MEQQSQLERLGLFDARVPRYTSYPTAPHFTPAVGEPVFRDWIAAIPAGAAISLYMHVPFCRRLCWFCACRTQGTQSDEPVRAYAKALLAELDMLKSALAPGVRLSRLHWGGGTPTLMPAEMMRLVAGAVLDAFPLAEGAEFSVEIDPNEIDEARMDALAEAGLNRASIGVQDFDPEIQKIIGREQSFEVTKRAVDMIRDRGIASLNADILYGLPHQDPHRIAESVQKLLALSPDRVALYGYAHVPWMAKRQVMIPSEALPDPHGRLRLFETARELFLADGYDEIGIDHFARPGDGLARAQKAGLLRRNFQGYTDDRAEVLVGLGASSISRFPQGYAQNAPATGAHLARIRDGRFSTTRGHAFSAEDRWRSRMIEALMCDFEIRAEEFIRDHGFDAESLSRILTPVAAHFGDMVDADASGLRITPRGRPLTRMIARMFDGYDMAASGHSAAI
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
What are the official names of this protein?
Oxygen-independent coproporphyrinogen III oxidase, CPO, Coproporphyrinogen III dehydrogenase, CPDH.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMTL2_HUMAN
Sequence: MEPAPDAQEARTVREALGRYEAALEGAVRALHEDMRGLQRGVERRVAEAMRLAGPLARTVADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTPSPPPAPGVPDRAPRLGSARFASHATFSLSGRGQSLDHDEASESEMRKTSNSCIMENGHQPGAGPGDGPPEIAQNFSAPDPPRPRPVSLSLRLPHQPVTAITRVSDRFSGETSAAALSPMSAATLGGLNPSPSEVITPWTPSPSEKNSSFTWSVPSSGYGAVTASKHSNSPPLVTPPQSPVSPQPPAITQVHRQGERRRELVRSQTLPRTSEAQARKALFEKWEQETAAGKGKGEARARLKRSQSFGVASASSIKQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNHLRRFE
What are the official names of this protein?
Smoothelin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the smoothelin family.
Protein: DPO4_STRTD
Sequence: MLEFPLINDTSRKIIHIDMDAFFAQVEMRDDPSLKDKPVIIGNDPRKTGGRGVVSTCNYEAKKYGVHSAMSSKEAYERCPNAVFISGNYSHYREVGMQIREIFKCYTDLVEPMSIDEAYLDVTTNKLGIKSAVKVAKLIQYDIWQELHLTCSAGVSYNKFIAKLASDFQKPAGLTVVLPEEAQEFLKKLPIAKFHGVGKKSVERLHDMDIYTGADLLKISEITLIDRFGRFGFDLFRKARGISNSPVKPNRVRKSIGSERTYGKLLYNEDDIKAELTKNAKRVAESAQKAKKVGRIIVIKVRYSDFSTLTKRMTLDKSTQDFDTIDRISHSIFDQLEENSSGVRLLGVTLTGLEDQEGRQLDLDDLA
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGNB2_XENTR
Sequence: MARLVAVVKYSDEDYPFEKRQMPLYIDDSLTMVLEFSDNMLNLDKQQIDTVQLEQFIQRHRMLKEQDLASAMTVTSREVFNALSQLLPCVGCRRCVERLFSQVMQTGIQALDPLSVGANGVLTLSHGFMTDATKLYTLFYMCGSKMNNELDAIAKNKKGKKNNRCKFHSLDVRKPKPVGGHWMDVWEVMSPECRDEVALIDSNCLLETLENYLQKHRFCADCKNKVHRAFNILTGELDFSKVKGYCANVYQGLRCCPHEGHIHLCCETDFIAHVLGRAEPEFAGGYERRERHAKTIDVAQEEVLTCLGIHLYERLHRIWLKLRAEVQTRQMLFYLGVDALRKSFEVTVEKVRGISRMDQYFKDILEEEKVQELKQEKKRQKKNRKKNKSSCDLPTPLETKSANPSQKNEPPGFMESDGNPCNISEDSNMCAEVTVKNEDLLRSHKVKKGLTPHSNVSDCGYSSSLEGSEPGSQEGSDVACAEGICKHDEAGDDKEEEEGDSCVECWNNCTKDNIKGKNKKKKKKCKPFKCENENTLKQVPYNTESSDSVHSNPNEETKVYNFCMDSEFPRRPWIYHRNEFFSDMSSTESQTRFYSGRETKSLKELLDESECSSQEEDEITQDDIQAFKETYQTFYRDRQQFRQCLKENFKQFCLHQNPSLLVGNTGAIN
What is the function of this protein?
May be involved in spermatogenesis.
What are the official names of this protein?
Gametogenetin-binding protein 2, Protein ZNF403.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_SACD2
Sequence: MTNHEQDQQDNSELLDDDQVTLESQQAADSGAEAPASDDVAALQAEIARLNEELQTTKENALRAAAEAQNARRRAEQDVEKAHKFGLEKFVGDILPVADNLERAIDAAKAEGADLGVVVEGVELTLKTLVDGLKRHKVEQIDPQGEPFDPQLHQAMTMIEQPDVEPNTVINVFQRGYTLHGRLVRPAMVVVSKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_CROS5
Sequence: MSWQRPDGRQPNQLRPVNFELNFTRFSAGSVLAQCGETKVLCTASIEEYVPRFLLGSGQGWLTAEYRMLPSATQERQRRELLKLSGRTQEIQRLIGRSLRSCIDLQQLGERSITIDCDVLQADAGTRTTSITGGYVALALALNKLIKKGELIQSPLRFPVAAISVGLIEGEAFLDLNYPEDSKADIDFNVVMTGNLDLIEVQGTAEENSFTRSQLNDILDLAELGIKELVSLQNQALSQA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: MKAR_YEAS1
Sequence: MTFMQQLQEAGERFRCINGLLWVVFGLGVLKCTTLSLRFLALIFDLFLLPAVNFDKYGAKSGKYCVITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQHHVVVKILAIDIAEDKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKELRDIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQSWSNSLAGELSKDAIDVELIISYLVTSSMSKIRRSSLMIPNPQQFVKSTLRSVGRRCGSQERYATMTPYWAHAVYQFVITETFGVYSKIVNSINYSFHKSIRIRALKKAARQVKKE
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: YIBN_ECO57
Sequence: MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGEATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDGSGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK
What are the official names of this protein?
Uncharacterized protein YibN.
Protein: TYPH_RHOPS
Sequence: MNASHLSRPPLTIRRISLDTGRENVAVISRRSRALRADVFRGFSRVALRINTKVLLATLMITDDDAMIGPDELGLSEPAFRRFNEPVGSAVSVSPAQPPASLDAVRAKIQGHTLTPAEITAVIDDVAHFRYSDMEIAAFLISAARFTSTDELLALVDAMASVGTRLKWQNPIVVDKHCIGGIPGNRTTMIVVPIVAAQGLMIPKTSSRAITSPAGTADTMEVLARVDLDVEQMKRVVTTCGGCLIWGGHVNLSPADDILISVERPLSLDTPEQMVASIMSKKLAAGSTRLLIDFPVGPSAKIASASEAMRLRKLFEFVGDHFGIAVEVVTTDGRQPIGRGIGPVLEARDVMAVLGNEPNAPADLREKSLRLAAHLLEYDPLLRGGAGYARAKELLDSGAALKKMQQIIDAQGPSVCNSELGSHAADVLAPADGVVNGIDCLRINRLARTAGAPIVKGAGIDLFKKIGDRVDQGEPIYRIYASDRSELDLAIAAAEAESGFSVNHHSPAAVEPVS
What are the official names of this protein?
Putative thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: CWC27_ASPFU
Sequence: MSAHYTTEPPPTASATLHTTFGPIHIALFANQTPLTCKNFLQHCLDNYYAGTIFHRIVPDFIVQGGDPTGTGSGGTSIYEYPEFEYDPEARDPNEKVVLRDELHSRLRFNRRGLVGMAKSEDGTYGSQFFITLANAERELNGQCTLFGRVEGDSIYNVLKIAEAERVERTERPVYPVKVVSCEVGELGPFAGKLKRRETIATAPAAEEKPAAKKKKKAKGGKTLLSFGGDEGDEDVPLRPSKPKFNPTLVVDAGIPPANDAPKKTSPEAEQQTRKRPRSPSPRRSLSAERKHRPKTPDPLTQLPLPDPESPARSPPQSPPARQSILSRTRAEIENLKASMRRTVATGPADTGRKKSALEAMIPETAIRGRKRPPPGTVNGAGRGSSTNGVTGFSSAAEDETLRMFNAFKAKLESADAKSGPHGKTSISASDTTKYTSQAKSNTEPEDEEAQLCDLHFIANCQSCKSWDDTGTAEEAPDDDDRDWLTHELRFGKDMLGKDLQWKREHPDDVDSLVVIDPREREKEFVGGKRRGLERDRERDRKRERVGDQEWDRRRREKP
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Involved in pre-mRNA splicing (By similarity).
What are the official names of this protein?
Peptidyl-prolyl isomerase cwc27, PPIase cwc27, Rotamase cwc27.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PRH1_SCHPO
Sequence: MVKVSGKLRNGGSITKQNLTDGLVGGQRIKAPNKKKNRKASKNTTKKSTVSVVNFLEQDTDFGANEVVGSDNSSPEKRSENSPSKRKDILEQRKNLPIWEAHDTLCQQIQDNRVIVVVGETGSGKSTQIPQFLNECPYAQEGCVAITQPRRVAAVNLAKRVAAEQGCRLGEQVGYSIRFDDTTSKKTRIKYLTDGMLLRELINDPILSQYHTLILDEAHERTLMTDMLLGFVKKIIKKRPALRVIIMSATLNAERFSEFFDGAEICYISGRQYPVQIHYTYTPEPDYLDACLRTIFQLHTKLPPGDILVFLTGQDEIEALEALIKSYSKQLPSNLPQIQACPLFASLPQEQQLQVFLPALANHRKVVLSTNIAETSVTISGIRYVIDTGLAKIKQFNSKLGLESLTVQPISQSAAMQRSGRAGREAAGQCYRIYTEADFDKLPKETIPEIKRIDLSQAVLTLKARGQNDVINFHYMDPPSKEGLLRALEHLYSIGALDDNGHINDLGYQMSLIPLLPSLARAVLAAREHNCLSEVIDVVSCLSTDSMFLFPQEKRDEAIEARLKFLHSEGDLLTCLNALRQYLESSHDSRKQWCSQNFINRRALKTILDIRKQLREHCLKDGWELNSSPEVNSENLLLSFLSGYITNTALLHPDGSYRTIIGNQTISIHPSSSLFGKKVEAIMYHELVFTTKSYVRGVSSIRSNWLNAVAPHYLARRST
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Probable ATP-dependent RNA helicase prh1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
Protein: MSHD_RENSM
Sequence: MTTGPATPPQTNHAEDRTEWPIQVLRAAPETYLLQEILKLAEVAIDTDGHPPFSDQTLIQLRSANAPLLILLSYVPAAPEVPAALAGVAVVLEHDGQPASGTLELVVHPTYRNQGVGQVLLKSLQSARGFESLNAWSHGSHAAAQQLADQFGFEAVRALRRLRLALDAGHQLPAASLPTNISLRSFVPDQDEAAWLAVNAAAFAHHPEQGETSLADLKSLMEEQWFDAAGFLLAVDETDQIMGFHWTKIHAAPAGHQAIGEVYVVGIAPAAQGKGLGKALTLAGIDYLQKKGLSSIMLYVDADNTAAVSLYQSLGFARWDADTMYSYPSATNSNNKFQ
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: Y017_UREPA
Sequence: MLEKIKIIDTHTHPNIEPLIEEFDDIIFKCYEQGIGLNIVGVDLKTSQTAIQQAKKFKFLTCSVAIHPNDLHNIENDFVALEKLIAENIDYISCIGECGLDYYHEQNYDHDFQKHWFKKHIELAKKYHKPLMLHIRNAHDDAIAILKELAVQDVIIHCFTDKKEYAQQYIEMGYYISYPGVITFKPTKNNQLHELYEAIKITPLDKILVETDAPYLTPVPKRGQTNYPYYVLYTSAFIANLLGITHEKMQKILLENSLRILNFKK
What are the official names of this protein?
Uncharacterized metal-dependent hydrolase UU017.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Protein: YPT2_ECOLX
Sequence: MKITDHKLSEGIALTFRVPEGNIKHPLIILCHGFCGIRNVLLPCFANAFTEAGFATITFDYRGFGESDGERGRLVPAMQTEDIISVINWAEKQECIDNQRIGLWGTSLGGGHVFSAAAQDQRVKCIVSQLAFADGDVLVTGEMNESERASFLSTLNKMAEKKKNTGKEMFVGVTRVLSDNESKVFFEKVKGQYPEMDIKIPFLTVMETLQYKPAESAAKVQCPVLIVIAGQDSVNPPEQGKALYDAVASGTKELYEEADACHYDIYEGAFFERVAAVQTQWFKKHL
What are the official names of this protein?
Uncharacterized 31.7 kDa protein in traX-finO intergenic region, ORFC.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: YQEF_BACSU
Sequence: MKHFIILFLLLFVTAGCEGRGYEDVVAFGDSNTRGSNWDYRDYPKAQQWVNILKTAERGNLDILNAGIGGQTTEDARLRFQTDVLDQKPKYLFIMFGTNDAAILTEGKPRVSKQRFRENLVYFIEESRKHGIKPILMTCIPIIEGNGKHHLFYYSRYQAAAFEPKGGARKWHNSYNDITRDVSKRLDVPLVDNWKHFIEADGGKATDEALIQSGLIDPSGNHMTPKGARIVYEGIQDGQILQR
What are the official names of this protein?
Uncharacterized lipoprotein YqeF.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NUON_MARMM
Sequence: MTADMLSHDLSLLIPELVLAGGAMALLMLGVFLKGDGTEKLVQWLTVGLLAAAALAALFLVSGEGMAFNDSFVFDSLARFSKTAIGLVAAIAMLLAMPYLQAEKLGKIEYPVLVVLAVTGMMMMVSANDLIAMYMGIELQSLALYVLAAFNRDSLRASEAGLKYFVLGALSSGLLLYGASLVYGFAGSTGFGDIALAVESGSNIGLTVGLVFVICGLAFKVSAAPFHMWTPDVYEGAPTPVTAFFATAPKFAAIVLLARVLMEPFGAVVDQWRDVIWMIAVLSMAVGAFGALTQQNIKRLMAYSSISNMGYALVAVAAASQTGLWALLVFMVLYMVGAIGSFATILSMRTREGMVEQISDLAGLAQRNPGLGWSMTALMFSIGGLPFMVGFFGKFFVIYAAVQADLMILAVLAVLFSVVGAAYYLRIVKVIWFDSSEIEFVPSAVSTYWIARIAGLATVLLLPVLGWLVFRAYSVGLALL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLIE_BURVG
Sequence: MVANVSGIGSVLQQMQAMAAQANGGVASPAAALAGSGAATAGTFASAMKASLDKISGDQQHALGEARAFEVGAANVSLNDVMVDMQKANIGFQFGLQVRNKLVSAYNEVMQMSV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: EX7L_ECO27
Sequence: MLPSQSPAIFTVSRLNQTVRLLLEHEIGQVWISGEISNFTQPASGHWYFTLKDDNAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQLKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHETDVTIADFIADLRAPTPSAAAEMVSRNQQELLRQIQSVQQRLGMAMDYFLANRTRRLTLLHHRLQQQHPQLRLARQQTALERLQQRMNLAIDSQIKRTNKRQVRLLQRLNQQNPQPRIHRVQSRIQHLEHRLAEHVHSRLSAMRERFGNAVTHLEAVSPLSTLARGYSVTTVTDGKVLKKVKQVKTGDVMTTRLEDGWVKSEVKGITSAKRAQKKKPD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARSA1_ECOLX
Sequence: MQFLQNIPPYLFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIGITIQAIASVPGLSALEIDPQAAAQQYRARIVDPIKGVLPDDVVSSINEQLSGACTTEIAAFDEFTGLLTDASLLTRFDHIIFDTAPTGHTIRLLQLPGAWSSFIDSNPEGASCLGPMAGLEKQREQYAYAVEALSDPKRTRLVLVARLQKSTLQEVARTHLELAAIGLKNQYLVINGVLPKTEAANDTLAAAIWEREQEALANLPADLAGLPTDTLFLQPVNMVGVSALSRLLSTQPVASPSSDEYLQQRPDIPSLSALVDDIARNEHGLIMLMGKGGVGKTTMAAAIAVRLADMGFDVHLTTSDPAAHLSMTLNGSLNNLQVSRIDPHEETERYRQHVLETKGKELDEAGKRLLEEDLRSPCTEEIAVFQAFSRVIREAGKRFVVMDTAPTGHTLLLLDATGAYHREIAKKMGEKGHFTTPMMLLQDPERTKVLLVTLPETTPVLEAANLQADLERAGIHPWGWIINNSLSIADTRSPLLRMRAQQELPQIESVKRQHASRVALVPVLASEPTGIDKLKQLAG
What is the function of this protein?
Anion-transporting ATPase.  Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate.  Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents.
What are the official names of this protein?
Arsenical pump-driving ATPase, Arsenical resistance ATPase, Arsenite-translocating ATPase, Arsenite-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
Protein: SERC_PHOV8
Sequence: MKKHNFNAGPSILPREVIEKTAQAVLDFNGSGLSIMEISHRAKDFQPVVDEAVALFKELLNIPEGYSVLFLGGGASLEFCMIPFNFLEKKAAYLNTGVWAKKAMKEAKAFGEVVEVASSAEATYTYIPKDYTVPADADYFHVTTNNTIYGTELHEDLDSPVPMIADMSSDIFSRPIDVSKYICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPTMLNYQTHIDGGSMFNTPPVLPIYAALQTLRWIKANGGVAEMQKRAKEKADMLYAEIDRNKMFRGTVTDKADRSYMNICFVMNDEYKDLEADFLKFATEKGMVGIKGHRSVGGFRASCYNAMPKESVQALIDCMQEFEKLH
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2603_MYCTO
Sequence: MSGHSKWATTKHKKAVVDARRGKMFARLIKNIEVAARVGGGDPAGNPTLYDAIQKAKKSSVPNENIERARKRGAGEEAGGADWQTIMYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTRNGGTMADPGSVSYLFSRKGVVTLEKNGLTEDDVLAAVLEAGAEDVNDLGDSFEVISEPAELVAVRSALQDAGIDYESAEASFQPSVSVPVDLDGARKVFKLVDALEDSDDVQNVWTNVDVSDEVLAALDDE
What are the official names of this protein?
Probable transcriptional regulatory protein MT2678.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_ACTP7
Sequence: MSRTKKTRRITDIMPARKADKKPEQPKLSGGKNRKPTRYELDAKAREEKKKRKHKGLPTGSRNVDPAEQKKAAVKEVKDPRIGSRKKIPLMVEFVNKPEKGQIIKPVAVEEYKPHLSPELELEQLENNEILNQLLDEIEAGKTLSAKDQKFVDECLDRIDELMTELGIQDEDEDNGDALLRQFETMDINQFR
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: PNPH_DROPS
Sequence: MENNLAPINEDPFPIKIGIIGDADLDTTISLQDRMEYAVCTPFGKPSDIIIEGLIDGVKCALLCRNGRLHDIMPTNINYRANIWAMRKLGCTHILVTHSLSSLREDIMPGDFVVPNDLIDHTTRRAQTFYDGALGSPFGVCHLPMYPAFCERTRQHLLNAAQELDLATHSKATVLTLEGPRYSTLAENNIYRKWGADLLSMTLSPEATLAKEAGILYASIGLVTNIECWCANQPIATTHEIIYVFKNKVEKLQQVLSKAIANISKEDWSEDILKAKILVCSNFANRNK
What is the function of this protein?
Purine nucleoside phosphorylase involved in purine salvage.
What are the official names of this protein?
Purine nucleoside phosphorylase, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: 3HAO_BACAH
Sequence: MSKTLQSFNLLKWIDENKELLKPPVNNKVIWQDSEFIAMILGGPNRRRDFHVDPSDEFFYQIKGECYVECITEEGKREVVTVKEGDVFMLPAMVPHSPHRVANTYGLVIERKRSQGELEDFVWFCDECNHEMHRVRVQLSDIEKQVKEAIHSFNSNKEIRACKNCGHIMPEEVGEWKCE
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
Protein: SDMT_HALHR
Sequence: MATRYDDQAIETARQYYNSEDADNFYAIIWGGEDIHIGLYNDDEEPIADASRRTVERMSSLSRQLGPDSYVLDMGAGYGGSARYLAHKYGCKVAALNLSERENERDRQMNKEQGVDHLIEVVDAAFEDVPYDDGVFDLVWSQDSFLHSPDRERVLREASRVLRSGGEFIFTDPMQADDCPEGVIQPILDRIHLETMGTPNFYRQTLRDLGFEEITFEDHTHQLPRHYGRVRRELDRREGELQGHVSAEYIERMKNGLDHWVNGGNKGYLTWGIFYFRKG
What is the function of this protein?
Catalyzes the methylation of sarcosine and dimethylglycine to dimethylglycine and betaine, respectively, with S-adenosylmethionine (AdoMet) acting as the methyl donor (PubMed:10896953, PubMed:11319079).  It has strict specificity for sarcosine and dimethylglycine as the methyl group acceptors (PubMed:11319079).
What are the official names of this protein?
Sarcosine/dimethylglycine N-methyltransferase, SDMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: MNME_YERP3
Sequence: MSTTDTIVAQATPPGRGGVGILRVSGRAASEVAHAVLGKLPKPRYADYLPFKDVDGSTLDQGIALYFPGPNSFTGEDVLELQGHGGPVILDLLLKRILALPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSAVNSLQGAFSARIHQLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEGQLNGVMADLEQVRTEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHINGMPLHIIDTAGLREANDEVERIGIERAWNEIEQADRVLFMVDGTTTDATEPAAIWPEFMARLPATLPITVVRNKADITGETLGLTEVNGHSLIRLSARTGEGIDLLRDHLKQSMGFTSNTEGGFLARRRHLQALETAARHLIQGHEQLVSAYAGELLAEELRLAQQSLSEITGEFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMLA_SALTY
Sequence: MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGHDDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDQKGTAVSLEEKPLQPKSNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKNFINAQQVIELAGPLSKNDYGKYLLKMVKGL
What is the function of this protein?
Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.  Is the first of four enzymes commited to biosynthesis of dTDP-L-rhamnose in S. typhimurium LT2.  Is also able to convert non natural substrates such as a wide array of alpha-D-hexopyranosyl, deoxy-alpha-D-glucopyranosyl, aminodeoxy-alpha-D-hexopyranosyl and acetamidodeoxy-alpha-D-hexopyranosyl phosphates to their corresponding dTDP- and UDP-nucleotide sugars.
What are the official names of this protein?
Glucose-1-phosphate thymidylyltransferase, dTDP-glucose pyrophosphorylase, Ep, dTDP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the glucose-1-phosphate thymidylyltransferase family.