PharMolix/UniProtQA huggingface dataset:
Protein: REP_HAEIN
Sequence: MKLNPQQQQAVEYVTGPCLVLAGAGSGKTRVIINKIAHLIEKCGYSPKQIAAVTFTNKAAREMKERVAHSIGKEQSKGLLVSTFHTLGFDILKREYKALGFKSNMTLFDEHDQFALLKELTADVLKEDKDLLRELISVISNWKNDLISPKQAFALARDAKYQTFAKCYERYATQIRTYNALDFDDLIMLPTLLFKQNEEVRSKWQAKIRYLLVDEYQDTNTSQYELIKLLVGDRACFTVVGDDDQSIYSWRGARPENMVRLRDDFPRLNVIKLEQNYRSTQRILHCANILIDNNEHVFDKKLFSTIGKGEKLLVIEAKNEEHEAERIVAELIAHRFSRKTKYKDYAILYRGNHQSRLLEKVLMQNRIPYKISGGTSFFSRAEIKDMMAYLRLVVNQDDDAAFLRIVNTPKREIGTATLQKLGELAQEKHISLFEAIFEFELIQRITPKAYDSLQKFGRWIVELNDEIQRSEPERAVRSMLSAIHYEEYLYEYATSPKAAEMQSKNVATLFDWVADMLKGDETNEPMNLNQVVTRLTLRDMLERGEDDDDSDQVQLMTLHASKGLEFPYVYLIGMEEGILPHQTSIDEDNVEEERRLAYVGITRAQKELTFSLCRERRQYGELVRPEPSRFLAELPNDDVLWERDKPKLTTEQKQEKTQNQLDRLRAILKS
What is the function of this protein?
Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA.  It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
What are the official names of this protein?
ATP-dependent DNA helicase Rep, DNA 3'-5' helicase Rep.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: RLMH_STAHJ
Sequence: MKITILAVGKLKEKYWKQAISEYEKRLSAYSKIEIIEVPDEKAPENMSDKEIEQVKEKEGQRLLAKIKPQATVITLEIQGKMLSSEGLAEEMQRRMTQGQSDFVFVIGGSNGLHENVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_SHELP
Sequence: MLVYLAEYLTQFYTGFNVFSYVTFRAILGLLTAMVFSLWWGPKMIERLQLLQIGQVVRNEGPESHFAKRGTPTMGGLLILAGVFISVLLWGDLGSRYVWVMLFVLGAFGLIGFIDDYRKVVRKDTKGLIARWKYILQSLAALAIAFYLYASAGSEGETQLVLPFFKDVMPQLGAFFILLAYFTIVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLSGHVQFANYLHIPYLPGSGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLSLGAALGTIAVLVRQEILLVIMGGVFVMETVSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLFLVLLGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SRA6_CAEEL
Sequence: MSNLSCAAPDVLERLDSFNMKLSQFVDLLAIILAFFASYFAIKIVINQSFFELSTKILLLQNLFYTNLYQISYGIEAIGMLYRGFFMLSEPCSILQSETSCAPYFKVLMIGTSGMIFGQTGLLIERAFATFATTYKTKKSVYIGVCISLIVLVCSTSSGFIILWDDPLEGWTIGCFAVSKSVVPRFNLFSILSTVLTLFNLIVSIFIQRYNKRFEFETRFKVGARFQKQELIESTGAICFLALSQFLWMFMYSFGILILRIIREDILPSTFYFWIAWCYTMPFIALMFPVLLIYRIRKTRARRTEKMKGITTEKQTQDDHIKQINAMWT
What are the official names of this protein?
Serpentine receptor class alpha-6, Protein sra-6.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TIM29_MOUSE
Sequence: MVTAALKRFWSGGHGEAGGEAGGATTVAVKPGLWTRLSTWAGALLRDYAEACGDAAAAARARPGRAALYVGLLGGAAACCALAPSEAAFEEALLDASGSLLLLAPATRNRHSEAFLQRLLWLRGRGRLRHVNLGFCSLVYEAPFDAQASLYQARCRYLQPRWVDFPGRILDVGFVGRWWILQNRMHDCDINDDEFLHLPAHLRVVAPHQLHSEANERLFEEKYKPIILTDDQVDQALWEEQVLQKERKDRLALSEADSLVQSDVSR
What is the function of this protein?
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force.  Required for the stability of the TIM22 complex and functions in the assembly of the TIMM22 protein into the TIM22 complex.  May facilitate cooperation between TIM22 and TOM complexes by interacting with TOMM40.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim29, TIM29.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Protein: PTH_BACCN
Sequence: MKLIVGLGNPGREYELTRHNIGFMAIDELAKRWNISLNEQKFKGMFGAGFVNGEKVILLKPLTYMNLSGESIRPLMDYYKIDLEDFIIMYDDLDLPVGKLRLRMKGSAGGHNGVKSTIAHLGTQEFQRIRMGIDRPKNGMKVVDYVLGRFTAEEMVDVNHAIEKAANACEEWLNKSFLQVMNDFNN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_PROMT
Sequence: MNKNKSNKLKGIVVALKANFLIVEIDHKNFKDHSFDQFYGKIRLLCIRRSKLNYQGLFIDVGDIVCVESIDYKNKRAVVSDVEPRQSFLKRPAVANVTLVSICISADEPLFDMEQTSRFLLTAECANIEPLIILTKIDLITKNDLILYINKFKSWGYDCIPVSIHNSQGIDSLIERLRKTKLTVLAGPSGVGKTSLINHLIPTVSLPTSSVSKKLKRGTHTTRHVELFAIGNGSLLADTPGFNRPEIVCEPSDFAFLFPEFRTQLSNSQCKFRNCLHRDEPGCVIDKDLERYPFYRQNLEEMINSPLPYQAG
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_STRR6
Sequence: MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAETAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSPDIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRLAELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDKVIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVAESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALKEAVK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHH7_PENJP
Sequence: MSLAMTAFRMMAVALVVVVASSTTWARSLEGSSSPVTSLTRGRSLNKRAAFDPSCTGVYDRELLGRLSRLCDDCYNVFREPKVAMECRSNCFFNPAFVQCLEYLIPAELHEEYQALVQTVGK
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction.
What are the official names of this protein?
Crustacean hyperglycemic hormones 7, Pej-SGP-VII.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_VARPS
Sequence: MKHAIRHIHFVGIGGSGMSGIAEVLFNLGYRITGSDLADSATLRRLAGLGIGTFVGHAAAHIDGADAVVTSTAVQSDNPEVLAAREKRIPVVPRALMLAELMRLKQGIAIAGTHGKTTTTSLVASVLDAAGLDPTFVIGGRLNSAGANAQLGSGDYIVVEADESDASFLNLLPVMAVVTNIDADHMETYGHDFAKLKKAFVDFLHRMPFYGVAILCTDDPAVRDIVAEVTCPVTSYGFGEEAQVRAIDVRAVGGQMHFTAQRRNGVTLPDLPIVLNLPGEHNVRNALSVIAVAVELGIPDEAVQRGLAGFKGVGRRFQSYGEVAAQGEPAGSFTVIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFEDFVKVIGNADAVLLGEVYAAGEPPIVAADGRTLARALRVAGKVEPVFVDDIGAMPQAILDNARAGDVVLCMGAGSIGAVPGKVVEIAAAASLPQQTTRTRRKGEAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCXE_BUTOC
Sequence: MSSLMISTAMKGKAPYRQVRDGYIAQPHNCAYHCLKISSGCDTLCKENGATSGHCGHKSGHGSACWCKDLPDKVGIIVHGEKCHR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin is active only on insects.
What are the official names of this protein?
Alpha-insect toxin Bot14, BotXIV, Neurotoxin XIV.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP8_ORNAN
Sequence: MPQLDTSTWYTTILLMILAIFCIFQLKMIKHLYMNVPLILNQELFIKHQTPWHSKWTKIYLPPSLLLQS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: LIPA_ACIET
Sequence: MSTPDVVREAQSTEAYNPLAKQKAAAKLSRIPIKVEQGEVLKKPEWIRVKAGSPTTRFYEIKNILREHKLHTVCEEASCPNIGECFGRGTATFMIMGDKCTRRCPFCDVGHGRPDPLDKDEPLNLAKTIAALRLKYVVITSVDRDDLRDGGSGHFVECIQRTRELSPSTQIEILTPDFRGRDDRALEILKAAPPDVMNHNLETVPRLYKEARPGSDYQFSLNLLKKFKQLHPGVPTKSGLMVGLGETDEEILEVMRDMRAHGIEMLTIGQYLAPSNSHLPVRRYVHPDTFKMFEEEAYKMGFSHAAVGAMVRSSYHADQQAHAAGV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL332_MYCPA
Sequence: MASSTDVRPKITLACEVCKHRNYITKKNRRNDPDRLELKKYCPNCGKHQAHRETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DNAA_GEOTN
Sequence: MENIHDLWDRVLGEIERKISKPSFETWLKSTKAHSLRGDTLVIVAPNEFARDWLDSRYSHLIAETIYAITGEELAVKFIIPPNQADEKLELPSSAKKQRKPYEEANDFPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPSAKVVYLSSEKFTNEFINAIRDNRPDDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNTLHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGFDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKEITADLAAEALKDIIPSAKPKVITIQDIQRVVGQHFNIKLEDFKAKKRTKSVAFPRQIAMYLSRELTDCSLPKIGDEFGGRDHTTVIHAHEKISKLLQTDTQLQKHLKEIQEKLKQL
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS2_STRPF
Sequence: MVLSDIEIANSVSMEPISKVADQLGIDKEALCLYGKYKAKINARQLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLKAGGALADLLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVQKTDLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACNKRGVDVVISDVWANGGAGGRELAEKVVTLAEQDNQFRFVYEEDDSIETKLTKIVTKVYGGKGITLSPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKTLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 2, Formyltetrahydrofolate synthetase 2, FHS 2, FTHFS 2.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: TR43A_MOUSE
Sequence: MESDNLQDPQEETLTCSICQSIFMNPVYLRCGHKFCEACLLLSQEDIKFPAYCPMCMQPFNQEYINDISLKKQVSIVRKKRLMKYLNSKEHKCVTHKAKKMIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWRRLKIQQNYVEIERRTTLWWLSVKLREEVIKRVYGKQCPPLCEERDQHIECLRHQSNTTLEELRKSEATIVHERNQLIEVYRELMTMSQRPYQELLVQDLDDLFRRSKLAAKLDMPQGMIPRLHAHSIPGLTARLNSFRVKISFKHSIMFGYTSVRPFDIRLLHESTSLDSAETHRVSWGKKSFSRGKYYWEVDLKDHEQWTVGVRKDPWLRGRSYAATPTDLFLLECLRKEDHYILITRIGGEHYIEKPVGQVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFSAVYT
What are the official names of this protein?
Tripartite motif-containing protein 43A.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: MAGI3_XENTR
Sequence: MSKTLKKKKHWLSKVQECGLSGVGGDPCSLLEIRGGAEHGEFPYLGRQREDVASFIVGKVPSQGDVLLEVNGTPVSGLTHRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRSPRDGEVPGVDYNFISVEQFKALEDSGVLLESGTYDGNFYGTPKPPAEPNPFQADPVDQVLFDGEFDTETQRKRTTSVSKMQRTDSSLPEEEDEEEREAVNGSSGSTDHRDRQEPSEWGKTVPSYNQTNSSMDFRNYLTRDENLEPLPKNWEMAYTEAGMIYFIDHNTKTTTWLDPRLCKKAKAPEDCEDGELPYGWEKIEDPQYGTYYVDHINQKTQFDNPVLEAKRKKQLNPAPSEGTVHQEPENSQFTRDPSQLKGALLHTSLKKSAMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGTCVLGHTHAEVVQMFQLIPINQYVNMTLCRGYPLPEDSDDPVADIVNTVPPIINGQMLTQGDINMGSQELKSGVIDLDQRGKPGLMVVNGRLNGPSLDIQDQRTSMASSGNSLPELVTIPLLKGPKGFGFAIADSPMGQKVKMILDSQWCPGLQKGDVIKEICHQNVQNLTHIQVVEVLKQFPVGAEVPLLILRGGPPSPSKVTKVKSDKQELMGSIEAIAPGEPLPQPLPFPPNLARSCSPKLDPSEVYKKSKNIFEDKPPNTKDLDVFLRKQESGFGFRVLGGDGPDQAIYIGAIIPLGAAEKDGRLRAADELICIDGVPVKGKSHKQVLDLMTNAARNGHVLLTVRRQIYYTDKQQEEEELQHTPPAHNGSPRLNRIEVSAIPKLPAEAYDVILQRKDNEGFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCRKLKVGDRISAVNGQSIVELSHDNIVQLIKDAGNTVTLTVIAEEEHRGPPSGSNSARQSPAPQHRPMGQTQPTYGTLDRYSWSDHKADCGPALPAGSWQALSVGCYPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINNEPTQGITHTRAIELIQAGGSKVLLLLRPGTGLIPDYSLAPSSLCSYVKPDQQ
What is the function of this protein?
Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes.
What are the official names of this protein?
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3, Membrane-associated guanylate kinase inverted 3, MAGI-3.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell junction, tight junction.
Protein: MUTL_BRUA1
Sequence: MTIRHLSETIINQIAAGEVIERPASVIKELVENAIDAGATRIEVVTAGGGKTLLRVTDNGSGIPADELALAVSRHCTSKLTDDVHDIRALGFRGEALPSIGSVSKLTLKSRPQDADSGFEVCVTGGHLDGPRPTALNRGTIVEVRDLFYATPARLKFMKTDRAEATAITDVVKRIGIAFPHIRFSLAGTDRTPFEMPATGTGAEATLERIGQVLGREFGENALAIDAERDGVRLAGFVGIPSFNRGNALHQFAYVNGRPVRDKQIFGALRGAYSDVIARDRHPVAVLFLTLDPALVDVNVHPAKADVRFRDPGLVRGLIVGAIKQALAQSGIRPATSGAEAMLQAFRAEGFGAQQSAPRPANSYSPASWRTAPPAPRSEWSPQTAHPAHRPLDLQAAPALRENGQAVLGDVAVPAADARASVAEAPVELMQKPLGAARAQIHENYIVAQTEDSLVIVDQHAAHERLVYEALKNALHARPIAGQMLLIPEIVDLPEEDAQRLAGHAETLARFGLGVEQFGPGAIAVRETPAMLGEMNVQQLIRDLADEIAEHDTADGLKAMLHHVAATMACHGSVRSGRRLKPEEMNALLRDMEATPGSGTCNHGRPTYIELKLTDIERLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: END4_ECO55
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: REG9_PYRAB
Sequence: MAEILDKVDRRLLEELKINARENIATLSKKLGIPRTTVHYRIKRLVEEGIIERFTIKPNYKKLNLGTTAFILIRYDPDSGLTQRQVAEQIAKIPGVYEVHIIAGEWDLLLKVRASNAEEVGRIVIDKLREIRGVGQTVTMVSFDTVKEEI
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator PYRAB16920.
Protein: YIDZ_ECOHS
Sequence: MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELAAESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSRELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHETWNLDTFLRYPHISICWEQSDTWALDNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPLPFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA
What is the function of this protein?
Involved in anaerobic NO protection.
What are the official names of this protein?
HTH-type transcriptional regulator YidZ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: FDHD_YERPG
Sequence: MSQIKPSRLSSSAEIRGARQLDVLQRHKLAEPQQDWLAEEVPVALVYNGISHVVMMATPKDLAAFALGFSLSEGIISSPQEIYSIEMTPGCNGIEVNIELSSRRFAGLKERRRAMAGRTGCGVCGIEQLDDIFRPITPLPFTQAFNLEHLDTALAQLKQVQPVGQLTGCTHAAAWINPEGELLGGCEDVGRHVALDKLLGIRAKQPWQQGAVLVSSRASYEMVQKTAMCGAEILFAVSAATTLAVEVAERCNLTLVGFSKPGRATVYTHPQRIK
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_LEGPA
Sequence: MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPGVLMLEALAQACGILANLSRQPKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLAGQKRDFWRMHGEAYIGDKLACSADLLSAAKEIKK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_SHEDO
Sequence: MLKIYNSMSREKQEFKPITPGKIGMYVCGITIYDLCHIGHGRTFVSFDMIVRYLRYLGYEVNFQRNITDVDDKIIKRAAENNESCDALTERLTAEMHKDFDALNMVRPDFEPKATLHMPEIIEMVQRLLDRGHAYVAPDGDVLFSVASYKEYGRLSGQNIDQLQAGARVEIDHNKQNPMDFVLWKMSKPGEPTWESPWGAGRPGWHIECSAMNGKHLGTHFDIHGGGSDLQFPHHENEIAQSCCAHDTPYVNYWMHTGMVMVDREKMSKSLGNFFTIRDVLKHYDAQTVRYFLLSGHYRSQLNYSEDNLKQARSALERLYTAFKDLDLTVTAAPADEYVTKFKSAMNDDFNTPEAYSVLFDMVREINRLKTTDMGAASALGVSMKQLADVLGIVSVDIETFFKGSGSDDEVAEIEALIVERNRARTEKDWAAADVARDRLNQLGVVLEDGENGTTWKKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_PSET1
Sequence: MKEGIHPKYEVISATCSCGNEFETSSTLCKNIHLDVCSACHPFYTGKQKILDTGGRVDRFNKRFGALGSKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: NDHI_PROMS
Sequence: MKNFLQQINSYIKEAFNAGKYLYNGLSVTFDHLRRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPVVDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATFDRHNLNFDNVALGRLPTNVTTDPSVKPLRELAYLPKGVMDPHEIPASDTRVGKLPEEVYDWMRPESNKNKDKVSNSNN
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: YACG_RHIL3
Sequence: MPEDKKAAAKVEPLRKTRPCPECGKPSNREHYPFCSNRCREADLSRWLTGAYAIPVADDETKAEYPDGEN
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: RS12_PSYA2
Sequence: MATTNQLIRKGRKTIKEKSKVPALEACPQRRGVCTRVYTTTPKKPNSAMRKVCRVRLTSGYEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGALDCAGVKDRKQGRSKYGAKKPKV
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.