PharMolix/UniProtQA huggingface dataset:
Protein: PNP_CAMHC
Sequence: MKYAVEVNNNVEIFEINKVAKQAAGACLMKVKNTVVLATVARENTQVEEDFLPLTVQYIEKQYAAGRIPGGYIKRETKPGDFETLTSRIIDRSLRPLFPKGYAYPTQIVVFVLSADPEIDLQVVGLNAASVALYLSDIPMKAPVCGVRVGYINDSFVINPTNSELQNSALDLYVAGVKDEMLMIEMRSLPNMNGENQNMNEFSEDKMVEAIDFASKAILAGSTAYENTFSALKKPDAALEYKPEVEDENIANFIEQNFTSDVQAAINQMAKSERATELDKIVNKIMQSETAIQNEWQKNVVSNIIGKFKRKIIRSQIINERRRADGRALDEIRPISIETNILPNAHGSCLFTRGQTQALVVTTLGGETDAQVSDSLTSNTPISERFMFQYNFPGFCVGEASPLKSPGRRELGHGNLAKRALTPSVPLNNPQVIRTVSEILESNGSSSMASVCGGSLSLRAAGVSTLKLVAGVAMGLIFEDDKHAILTDIMGLEDHDGDMDFKVAGTREGITALQMDIKLGGISLEILREALNQAKDGRNYILNLMEVANDDIIINEEILPKIEIFGVDPNKMVDIIGQGGKTIKELIDKYEVSIDLERDSGEVKIQGANKINVENAKSDILNIVKKSNDFKKGSKFGHHHERKETSNFQVGEEFDGVVKKIMDFGAFISLKDGIDGLLHVSKIKTQLSEGDTLRVKVEEIKRGKISLELCE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARA_STAA3
Sequence: MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
What is the function of this protein?
Global regulator with both positive and negative effects that controls the expression of several virulence factors and the biofilm formation process in a cell density-dependent manner.
What are the official names of this protein?
Transcriptional regulator SarA, Staphylococcal accessory regulator A.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2_THAPS
Sequence: MTSASIHIGSYTSTTNGNTTVVKAPTKESLSTCLSATATTTSPLDSIDIYINTSDLPTHYDSLALASIVPSLSPGGVLSVHVVSASSSAASNESAAVDVVNWSAITTSFVLAGLKAESEQRDGSGGRVYTARKATASQSASSAAATGRINLGGAKTKVKLSLDDDDDDQLIDEDDLLNGGGGMLAPPPTIDTEARAKSNLDDCGGRKACDNCTCGRAEQEAADAAGGPNEQQSKSSACGNCAKGDAFRCAGCPYLGMPAFKEGEEHLVLKLNDDV
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: MED20_DROME
Sequence: MGVTILQPYPLPEGKSGAHIIDQLSKRLLALGATHAGQFLVDCETFISTPQPHNGAPGRAVHVLHNSEYPASTFSIIDNGTGKQVAIVADNIFDLLMLKMTNTFTSKKQTKIESRGARFEYGDFVIKLGSVTMMEHFKGILIEIEYKSCVILAYCWEMIREMLQGFLGIAVNKDFPSYFAPQTIMTAMGQQQLHAKHNDIFEPMDTVKQYLEQFTNYRKHVTLMGGMGSGPGSQQVGPNVHMSPAVAGLHRS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Required for activated transcription of the MtnA gene.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, Protein trf-proximal, dMED20, dTrap26, dTrfp.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 20 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OBG_XANOP
Sequence: MKLVDEAEILVTAGHGGNGCVGFRREKFIPLGGPDGGDGGSGGSVWIVADENVNTLVDFRHERTFKAQRGENGMGRQAYGKGGEDRIIVVPVGTVVINVQTDEVIGDLTRHGDRLLVAKGGKGGLGNMHFKSSVNRAPRQSTTGEEGEERLLKLELRLLADVGLLGFPNAGKSTLIRAVSSATPKVADYPFTTLYPNLGVVSVEAYRSFVIADVPGLIEGAADGAGLGTQFLRHLQRTRLLLHLVDMAPMDGGVDGVSPADQVRTLERELERHDPQLLKKPRWLVLNKADLMFEDEARAAAETIVAELGWTAPWYLVSALGRDGTFPIMKDVMAFFDRQREDELEARNAG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFI2_PETHY
Sequence: MSPSVSVTKVQVENYVFPPTVKPPASTKTLFLGGAGHRGLDVEGKFVKFTVIGVYLEESAVQFLAPKWKGKSAEELIHSVDFFRDIVTGPFEKFTRVRFILPLTGKQFSEKVAENCVAHWKATGTYSDAGSRAIEKFLNVVKSETFLPGASILFTQSPLGSLTISFTKDDSISEAGNAVIENKQFSEAVLETIIGEHGVSPAAKCSIAARMSELFKNSLF
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase B, CHI-B, Chalcone isomerase B.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: MIAA_TROWT
Sequence: MLAVAFVGATGTGKSLLSLDAARDFNGHIVNADSMQLYRDMDIGTAKLSHSARQGIPHHQIDVIDPSSEASVARYKLSAQTCIKHIHALNSIPFLVGGSGLYVSSVVHNLQFPPTDGRVRKLLEDEADKSGIGVLHDRLLKLHPGFTVSRGNRRRIIRALEVAYITGRSPNPVLPLQNRANNFIVINLICDKGTLDIRLQKRVESFYDNGLIDEVRLLQEKYVLGRTAAKAIGYKQAIMYLAGEISCADAKDSTLQETIRLANKQIKWFRRYSGQHIVDTTDMSVAYEQIRSILNKSFRIS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PIWI2_SCHMD
Sequence: MEEIPVKVAKLEANGSETRGKMGNRGGLRGTFRIVEPNLQPADITEKTGNIGRTVKLQSNFTKFSVLRSEKFMMYDSVFSQVGLSPKVKLQFIVRVCQENKLPGAFCFDGRRLFTSEKWHGESDIQEFSHDEKKMTLRLVSTILPETEEYYQMINVLLNNLQVMLGQERIGKGYFLSPNITKDEVPRNSGPTFFETNSFKVLGGFGTTLQRGTKPTGELTTLLYIERINRVLNDNSVMKAYNRRSIDQLIGRDIITKYNNKTYRISEIKEMNVDEKFEMGGRTLSYAEYFKERYNIRLTQGDQPFVLTRVKKPMRRERKKKDEEGVEKEKEKEAPEEKDMTLNIPGELCFLCGFSDQEKSNMDLQKNLGCVLKREPRERLDDIPAYCNWIKNSDAATGMCNKWQLKIDNKPLEIEGRELPPCDVISGGSKINEKMGDDWKFGRVQFDIKRDRKHEIDVVIVDRNDFQYKNFMNDVEQELRNMRIDARVGKVNTCGPNDVERCLNDAARSGSGCAKMALVFVPDDRVYAKVKSFTMSTGLLTQCVTTRNGTNRNDKRRKVVSSKTVMQIFAKFGYDPWTVEIKLRPTMIVGMDTYHNKSSKKSIQASVFSINSTFTQYMSFVVNSPKGRQEFHETLGKNFNLALEDFKKRYDILPQRILVFRDGVGDNQLQFTKNFEVDAMKPLIENIYKGNGFPVPQIIYVIVKKRVGTKLFNRGNNPNPGTVVDKEIVKPNFYEFFLVSQRTTKGTATPTNYNVLEDTRLLTKKGTMDPMAPNELQKITYALTHLYFNWMGTIRVPVPVHYAHRLAELVGKVHKGSNPVAINERIRNRLFYL
What is the function of this protein?
Required for the production of functional progeny from adult somatic stem cells (neoblasts).
What are the official names of this protein?
Piwi-like protein 2, SMEDWI-2.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Piwi subfamily.
Protein: CAVEJ_VAEME
Sequence: ADCLAHLKLCKKNNDCCSKKCSRRGTNPEQRCR
What is the function of this protein?
This toxin stabilizes ryanodine receptor 1 (RyR1) opening in a long-lasting subconductance state (60% of the full conductance state) (PubMed:27114612).  Furthermore, it triggers calcium release from sarcoplasmic vesicles (31 nM are enough to induce a sharp release, and 65% of the total calcium is released after toxin (100 nM) addition) probably by acting as a cell-penetrating peptide (CPP) (PubMed:27114612).  In addition, it has been shown to dose-dependently stimulate ryanodine binding to RyR1 (EC(50)=3. 7 nM) (PubMed:27114612).  It also augments the bell-shaped calcium-[3H]ryanodine binding curve that is maximal at about 10 uM calcium concentration (PubMed:27114612).  It binds a different site as ryanodine (By similarity).  It acts synergistically with caffeine (By similarity).  In vivo, intracerebroventricular injection into mice induces neurotoxic symptoms, followed by death (By similarity).
What are the official names of this protein?
Vejocalcin, VjCa.
What is the protein family that this protein belongs to?
Belongs to the scorpion calcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VKTA_BUNCA
Sequence: MSSGGLLLLLGLLTLCAELTPVSSKDRPKFCNVPPEPGRCNANVRAFYYNPRLRKCIEFTYGGCGGNANNFKSRGECKRTCAE
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor A, Kunitz inhibitor A.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACP_CHLTB
Sequence: MSLEDDVKAIIVDQLGVSPEDVKVDSSFIEDLNADSLDLTELIMTLEEKFAFEISEDDAEQLRTVGDVIKYIQEHQN
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAC_RHIS5
Sequence: MQPFVYTTAPARIVFGTGSSVGVAEEIRRLGLSRALVLSTPHQKGDAEALAARLGPLAAGVFSDAAMHTPVEVTKRAVEAYRAAGADCVVSLGGGSTTGLGKAIALRTDAPQIVIPTTYAGSEVTPILGQTENGVKTTLRGPEILPEVVIYDAELTLGLPVGISMTSGLNAMAHAAEALYARDRNPIASMMAVEGLRAMIEALPGVRMEPQDTKARETALYGAWLCGTVLGAVGMSLHHKLCHTLGGSLDLPHAETHAVLLPYTIAYVEQAVPDQLAPLAALVGGRAGTGLYDFAARLGAPASLAALGVGGEDLDAMAELATANPYWCPRPVEKTAIRALLQRAFEGARPE
What is the function of this protein?
Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (PubMed:17158677).  Catalyzes the reduction of maleylacetate to 3-oxoadipate (PubMed:17158677, PubMed:27040018).
What are the official names of this protein?
Maleylacetate reductase.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: Y1205_PASMU
Sequence: MKKSEFKNSFIELLSNNIDNLNYDEKIHFIKKILTEYEIEKDKTDRTPVNKGQPWNDHQLELILSLPATKKNCLKFAKIFGRGYGSIEQIYRWASTPKNQLTKERLNDAFIQQIMRVKRNLELRN
What are the official names of this protein?
Uncharacterized protein PM1205.
Protein: OPGG_SHESM
Sequence: MVSLLRCQSFKPSSSLICSLALSAAFALSSSAFAEETKPAENKPATPVVSPPKATAQPANKNQVRFTKTGTFDGDSVVKLARKLASKPYVVLKDPLPAGLAKLSYDEYRDIRFNPVSSIWRDQGLPFQMQMFHRGFYFQDLIEIAIVEANQATHLAYEPKYFTAGEVITQALPNDDIGYSGFRIHNQLNTNGVYDELMVFQGASYFRALGKGNSYGLSARGLALKTADPEGEEFPIFRAFWVERPSYDSNLIVVHALLDSPSVAGAYRFSVRPGDNTQIDVEATLFPRVELSKVGLAPSTSMFLHSLNGRHDTDDFRPEVHDSDGLLMFNGRGEHLWRPLANPRQLQVSAFSDNSPQGFGLIQRERNYASYQDLEAHYERRPSLWIEPVGNWGQGAVVLTEIPTESEIHDNIVSFWKPRQPIPAGSEYHFAYRMSWGDEPVAKTNSVVVSRTASGRADIAKATPRRLFVVDYHLNGAMPDELPLAKVESSGGVIANVVIARNAANNGYRLAFELEPEDKELIELRAELKFSTPRQVETWLYRWTL
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: BIOB_ACIF5
Sequence: MNNSTALQTLDAILEIYARPFNDLIYAAQQVHRLHFDPNAIQCSTLLSIKTGGCPEDCGYCSQSVHHQTALQAEPLMDLEQVRAAAREAKANGAQRLCMGAAWRSPHDRDIEKVAAMIGVVKEYGLESCVTLGMLKPGQAERLQHAGLDYYNHNLDTSPEFYGEVIHTRSYQDRLDTLEAVRDAGIRICSGGILGMGESRRDRARMLQVLAQLPQAPESIPINALVPIPGTPLEAAEPIDGFEFVRTVAVTRILFPKAYVRLSAGREAMSDELQALAFLAGANSIFLGDRLLTTGNASTGHDQALFNRLGLHRSAD
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CNIH1_BOVIN
Sequence: MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS
What is the function of this protein?
Involved in the selective transport and maturation of TGF-alpha family proteins.
What are the official names of this protein?
Protein cornichon homolog 1, CNIH-1, Cornichon family AMPA receptor auxiliary protein 1, Protein cornichon homolog.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane. Note=Located primarily in the ER; may cycle between the ER and the Golgi apparatus.
Protein: RUVB_GLUOX
Sequence: MSDDYRETDPTRQPEDMGEGSLRPETLADFTGQKASRENLAIFIEAARARNEALDHVLLHGPPGLGKTTLAQIVARELGVGFRATSGPVIQRAGDLAAILTNLQPRDVLFIDEIHRLQPAIEEVLYPAMEDFQLDLIIGEGPAARSVRIDLAPFTLVAATTRAGLLATPLRDRFGIPLRLVFYTPEELRAIVSRGALKLGMRLTDDGAEEIARRSRGTPRIAGRLLRRVRDFALVSKHAVVDRALADAALGRLEVDERGLDAMDRRYLKRIAEHHHGGPVGVETLAAGLAEARDTLEDVIEPYLIQEGLVLRTARGRMLGEAGWRHLGLTPPASQVDLLSSLEQDDSAP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GLYA_RICFE
Sequence: MNIFNNHLHETDKEIDEIIKHEKLRQNSVIELIASENFVSPAVLEAQGSILTNKYAEGYSGKRFYNGCEEVDKAENLAIERVKKLFNCKYANVQSHSGSQANQAVYLALLQPGDTILGMSLDSGGHLTHGAAPNMSGKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGFSAYPRNIDFARFREIADKVGAYFMADIAHIAGLVATGEHQSPIPYTHAVTSTTHKTLRGPRGGLILSNDEEIGKKINSALFPGLQGGPLMHIIAAKAVAFLENLQPEYKSYIKQVISNAKALASSLQERGYDILTGGTDNHIVLVDLCKDGITGKLAANSLDRAGITCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGHMVADILDGLKNNEDNGKAEQKVLTEVTKLIKLFPFYTR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPYR2_CHLRE
Sequence: MSFYRGTASHPWHDLHPGNDAPNFVSCVIEIPRGSKVKYELDKDTGLCFVDRILYSSVVYPHNYGFVPKTLCEDGDPLDVLVLMQEPVVPMCFLRAKPIGVMQMLDQGERDDKLIAVHADDPEYKGFTDISQLPPHRLAEIKRFFEDYKKNEHKEVVVDDFLGAEEAKKVVKDSLNMYQEHYVPRKLRNVYE
What are the official names of this protein?
Soluble inorganic pyrophosphatase 2, Pyrophosphate phospho-hydrolase 2, PPase 2.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL28_SHEFN
Sequence: MSRVCQVTGKKPMVGNNRSHAKNSTRRRFLPNLQNHRFWLEEEKRFVQLRVSTKGIRIIDKKGIEVIVKELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: SAM37_YEAST
Sequence: MVKGSVHLWGKDGKASLISVDSIALVWFIKLCTSEEAKSMVAGLQIVFSNNTDLSSDGKLPVLILDNGTKVSGYVNIVQFLHKNICTSKYEKGTDYEEDLAIVRKKDRLLEYSLLNYVDVEISRLTDYQLFLNTKNYNEYTKKLFSKLLYFPMWYNTPLQLRSQARENCEEIIGSLTLEDDEEFVESKAMESASQLAQSKTFKIAHKNKIKGKQELQQVKYNLQFDNRLQSCVSNWLAARKKLDDSVILSSDLLFLANLYVQLGLPDGNRIRSKLEQTFGSELLNSMSNKIDDFVHRPSNNLEQRDPQFREQGNVVMSLYNLACKYI
What is the function of this protein?
Component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex.
What are the official names of this protein?
Sorting assembly machinery 37 kDa subunit, MAS37 protein, Mitochondrial 37 kDa outer membrane protein.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: RS12_CHLP8
Sequence: MPTIQQLIRHGRSMKASKTASPALEKCPQKRGVCTRVYTTTPKKPNSALRKVARVRLSNKIEVTAYIPGEGHNLQEHSIVLIRGGRVKDLPGVRYHIVRGSLDTSGVADRKQSRSKYGAKQPKAGAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL25_BORAP
Sequence: MENSRFLSCKYRSSFGSSNARRIRAKCEIPAVVYGQGNDVLHLKIKSSEFNKKFAKFTDNTVLILDDGKVERCVFVKDVAENIASKLIYHIDFYEVDKRVELEKYIPIKLVGASIGVKEGGILTVLKEQVKVRSLPLDLPEFIELDLTPVNKGDSVLLKDLVLPSNVKLAESDDNLEVVIIK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RNC_ALIF1
Sequence: MNSSLQRLEKKIGYQFKDESFLKLALTHRSANGTHNERLEFLGDSILSFVVADDLYHRFPKVDEGDMSRMRATLVRGHTLAELGREFQLGDYLYLGPGELKSGGFRRDSILADAVEAIIGAIYLDSDTETVRGIILSWYNTRLESIEPGVSQKDPKTRLQEYLQGRRKPLPTYTVTKIKGEAHNQEFTIECIVAGLDKPVIGKGSSRRKAEQSAADIALGQLN
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GELS_PIG
Sequence: LGALVVALCALSPPARAATASRGAPQARAPQGRVSPMRPSTMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVAVQRLFQVKGRRVVRATEVPVSWESFNRGDCFILDLGNDIYQWCGSNSNRYERLKATQVSKGIRDNERSGRAHVHVSEEDAEPAGMLQVLGPKPTLPEGTEDTVKEDAANRKLAKLYKVSNGAGTMTVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFISKMNYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQVDGPGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYRGGTSREGGQTAPASTRLFQVRASSSGATRAVEVIPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDSFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVVEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPINVVKQGFEPPSFVGWFLGWDDNYWSVDPLDRAIAELAA
What is the function of this protein?
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping).  It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (By similarity).  Plays a role in ciliogenesis (By similarity).
What are the official names of this protein?
Gelsolin, Actin-depolymerizing factor, ADF, Brevin.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
[Isoform 2]: Cytoplasm, cytoskeleton. SUBCELLULAR LOCATION: [Isoform 1]: Secreted.
Protein: EFG_CLOBK
Sequence: MANKEYPLAKFRNIGIMAHIDAGKTTATERILFYTGKTHKIGETHEGAATMDWMEQEQERGITITSAATTCFWKDHQVNIIDTPGHVDFTVEVERSLRVLDGAVTILDAKSGVEPQTETVWRQADNYKVPRMVFINKMDKLGADFLMSVGTLRERLHANAVPLQLPIGAEDSFSGIIDLVKNDAIIYKDDLGTVMDETEIPEDMKEMAEEYRTMLLEAVAEVDEDIMMKYLEGEEISVEEIKTALRKGVLANKIVPVLCGSAYKNKGVQLLLDAIIEFMPSPLDIEDVKGTEPTTGEEMTRPADAKAPLAALAFKIATDPFIGKLAFTRIYSGTMKSGTYVFNSNKGKRERIGRLVKMHANHREDVEELKAGELGAIVGLKDTTTGDTLCDDADPIILENMEFPEPVIDVSIEPKTKAGQEKMGIALAKLAEEDPTFRTYTNQETGQTIIAGMGELHLEIIVDRLIREFKVECNVGQPQVAYKETIKKHVKAEGKFIRQSGGRGQYGHCWIEMMPTEGEYEFQNAVVGGSIPKEYIPAIDNGIQEASQSGIIAGYPVINFKVKLFDGSYHDVDSSEMAFKIAGSMAFKNAMSKADAVLLEPSMKVEVVVPEEYMGDVIGDINSRRGRIEGMTPRAGAEVIRAFVPLSEMFGYATTLRSKTQGRGNYVMQFDHYEEVPKSIQDKVIGERK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.