PharMolix/UniProtQA huggingface dataset:
Protein: ABHEB_RAT
Sequence: MANVELSEGTIQVRGQSLFFREARPGNGQAVRFSVLLLHGIRFSSETWQNLGTLHRLAEAGYRAVAIDLPGLGRSKEAAAPAPIGELAPGSFLAAVVDALELGSLVVISPSLSGMYALPFLVAPESQLRGYVPVAPICTDKINAADYARVKTPTLIVYGDQDPMGSSSFQHLKQLPNHRVLVMEGAGHPCYLDKPDEWHTGLLDFLQELA
What is the function of this protein?
Acts as an atypical protein-lysine deacetylase in vitro.  Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues.  Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo.  Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate.  May activate transcription.
What are the official names of this protein?
Putative protein-lysine deacylase ABHD14B, Alpha/beta hydrolase domain-containing protein 14B, Abhydrolase domain-containing protein 14B.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD14 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: AL1A3_MOUSE
Sequence: MATTNGAVENGQPDGKPPALPRPIRNLEVKFTKIFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLAAALESGTVWINCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLEEKNP
What is the function of this protein?
NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid (PubMed:11044606, PubMed:11013254, PubMed:14623956).  Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde (By similarity).  Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region (PubMed:14623956).
What are the official names of this protein?
Aldehyde dehydrogenase family 1 member A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, RalDH3.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: MCM10_DANRE
Sequence: MTEEENLDMLLSLFAESEGQDLESPAAEEGEDNLDDLFDEDDDGEQYIEPEEAEEEKEEEEEEVSPGKSSSSDLNKSKEDLEAELKLMQEKMQKLQQQLEASQKTTPAQNKPAVQRQSTKSLTSPQAGVKTTPPTVRDSDGSPSNITAKLKNKQRTAHQPKAASSERQIPIGQSTNQPQPMRDGAKVNSMLKSPPLIKTPPTVRQPTPRLPVNQEVAVEKFSGLRLRKPRLSSIDIEQKMASRKLIRLSQLPDRLARDNLEDSDWVTFAVIINKITPQSKNNGKTFSIWKLNDLHNLEVNVSLFLFGSVHTDLWKTDTGTVIGILNPNPMKNKEGSNELSLTVDHPQKVLIIGEAMDFGTCKAKKKNGDSCTQLVNLYECQFCQYHVKAQYKKMSSKRAELQSSFTGSAPGKGRGRGSLKERLCQSDFHYGGMSSLACAPSMSAPQPKKQPTIQSALASIPTKKLVLNSGQVSGCSDDFRGLMSMPTPGALNIKRHLGQSKSSAVAGSSVQSVSASDLLKQQKEQHQQRMMARKKRAEEIQKRVLQSGGAPVASSRPNVSRGPLLSPKAASEGPKGSGSSLSGPAVPTLGRGFSEGEDIVFDMSPPSSKSLSATKLAAVRKLQAKGSVIVKEDPNAVKRKRANSGDITGRVERNIVKAKVTDENSASEEEEPAMKKRREQLEYIQSEEFQRILNAKSSNSWMMGEIEERAMQEYFEPLVQKEKMEEKMKSIREMKCRAVTCKTCKYTHFKPADRCVEEKHDYHWHDAVKRFFKCPCGQRKICLARMPHGACSHCGLFKWERDGMLKEKKGPKIGGELLMPRGEEQPKFLNSLK
What is the function of this protein?
Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.  Additionally, plays a role in preventing DNA damage during replication (By similarity).
What are the official names of this protein?
Protein MCM10 homolog.
What is the protein family that this protein belongs to?
Belongs to the MCM10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURG_PSE14
Sequence: MDANVLIMAGGTGGHVFPALACAREFQARGYKVHWLGTPRGIENELVPQAGLTLHLINVTGLRGKGRLSLLKAPFMLLKALMQARKVVRQVKPVCVVGFGGYVTGPGGLAAKLAGVPLIIHEQNAVAGTANRSLASFASRVCEAFPNTFAASSKRRTTGNPVRVELFLETPRQALTGRKARLLVLGGSLGAEPLNKLLPEALARLPQDIQPEVFHQSGKNHDAVTAERYRNVGVEAQVAPFIQNMAQAYSWADLVVCRAGALTISELAAAGLPSLLIPLPHAIDDHQSRNADYLAREGAAFVMPQATTGAAEMAARLKEVLMQPEQLNSMARTARSLAKPDATNTVVNVCVEVAHG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLMKL_SALHS
Sequence: MNSLFASTARGLEELLKTELEKLGAVGCQVVQGGVHFQGDTRLIYQSLMWSRLASRIILPMGECKVYSDLDLYLGVQAINWTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLHLRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDETIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSEPALIALHSLLGRTMKNQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLRKNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLKTRERQKGKNQYQKMSEKGEFLEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSKGKDFLNLFSYTGSASVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKRMEESFDVQRDHVALMKDLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLIRAA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_ACIAC
Sequence: MSDQQHSAPQNAAATASPSDSPEAVEATMAAHAADELGRLQNELAELKAKSADLADQFLRAKAEAENARRRADEEVSKARKFGIESFAESLLPVADSLTAALAIKDATIEQLREGTDATLRQLTSALERNKVLAIQPGAGEKFDPHQHQAISMVPAEQEPNTIVSVLQKGYVIADRVLRPALVTVAAPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED24_HUMAN
Sequence: MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 24, Activator-recruited cofactor 100 kDa component, ARC100, Cofactor required for Sp1 transcriptional activation subunit 4, CRSP complex subunit 4, Mediator complex subunit 24, Thyroid hormone receptor-associated protein 4, Thyroid hormone receptor-associated protein complex 100 kDa component, Trap100, hTRAP100, Vitamin D3 receptor-interacting protein complex 100 kDa component, DRIP100.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 24 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NQRD_PSEA6
Sequence: MADTKEMKKVLFGPILDNNPIALQILGVCSALAVTTKLETALVMSLALTAVTAFSNLFISMIRSQIPSSVRIIVQMTIIASLVIVVDQILKAYSYEISKQLSVFVGLIITNCIVMGRAEAFAMKSPPFISFLDGIGNGLGYSFVLIVIGTIKELFGFGTILGFEILPLIQNGGWYQGNGLLILPFSSFFLIGGLIWFIRTIKPEQVEPKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSXD_ECO81
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTLVQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGTVFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQVIFSGHTTSGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEEIMQYPIYSGILAGAGWQWVNLAWLAGGVWLLWQKAIRWHIPLSFLVTLALCATLGWLFSPDTLAAPQIHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWMIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YIAG_ECOLI
Sequence: MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKGTGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YiaG.
Protein: TPI1_GIAIN
Sequence: MPARRPFIGGNFKCNGSLDFIKSHVAAIAAHKIPDSVDVVIAPSAVHLSTAIAANTSKQLRIAAQNVYLEGNGAWTGETSVEMLQDMGLKHVIVGHSERRRIMGETDEQSAKKAKRALEKGMTVIFCVGETLDERKANRTMEVNIAQLEALGKELGESKMLWKEVVIAYEPVWSIGTGVVATPEQAEEVHVGLRKWFAEKVCAEGAQHIRIIYGGSANGSNCEKLGQCPNIDGFLVGGASLKPEFMTMIDILTKTRT
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICK11_TRILK
Sequence: MMKLYSLVIIATLAAAAFAATSEEISAAVGEIISQHQEDLERYAKVVERGEEPKKYIRCSKQLGESCYLNCECCGAAAVCEDYKYICKEKVSDNSVLNALGQAWNAVGNSISRYYCDAE
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
Toxin ICK-11.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. ICK-8 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ADEC_LACDA
Sequence: MTKIDLLVKNAHVFNVYLRKFEDVNITIKDGKFYWINKELPGIEAAKVIDLQGKYVIPGFVDAHMHIDSSMTTPKVMGQTIGKYGTTTIIADDHEITNVAGVKGLKDFIDEKAPIDIFFGIPSSVPSTNPNMETTGGLIGVKETEELLKDPRFVCLGEVMNFKDMTSDHDTLIKKIIAACRKARPTMPLEGHVPAYHSEDLAKVIYAGITTDHTQQTSSLVDEKIRSGMFVEIQLKSMHQEVIDTVIEHGYFEHVALVTDDSMPDTLLKGHLNLLVKKAIDMGMRPEDAIYISTYTPARHMGLWDRGAIAPGRVADFIVLNNLEDLSIAQVYKNGLPFAAKDEKDNNVYPEELLHSVKAPKLSEADFDLKTDLVQNGKVVANIIQINEVGTFTNHIQKCLEVKDGHVQWKKAGLALMLCQERYGKNEGRYAFALIDRGIVGDGAIGATWAHDHHNLIILGTNIAGMVSVQNLLVEEQGGYIAAKGSQIVANAPLPLGGVVSLEPMSVLGKQISKVRETMVDLGYKNTNEIMSFSTLSLLVSPTLKISDKGIFEVKTQRHIPLFEC
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: GLMU_SHISS
Sequence: MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKVGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_ALKCK
Sequence: MIVSLIATVLFGYLLGSVSFSYIIAKKIKKIDIRSEGSGNAGATNTLRVLGIGPAICVLLLDVAKGVAPALLAIALTNGDYPLVPALAGLAAILGHNWPIYFGFRGGKGVATSIGVVATLLFLPALCAGIVAILSIVFTKYVSLGSLLFAVLTPIAALIMLPFFHYPLEYIYLAVLLAILSLWRHRTNMGRLIAGTENKLGKKHA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IL10_RAT
Sequence: MPGSALLCCLLLLAGVKTSKGHSIRGDNNCTHFPVSQTHMLRELRAAFSQVKTFFQKKDQLDNILLTDSLLQDFKGYLGCQALSEMIKFYLVEVMPQAENHGPEIKEHLNSLGEKLKTLWIQLRRCHRFLPCENKSKAVEQVKNDFNKLQDKGVYKAMNEFDIFINCIEAYVTLKMKN
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF3_LISMO
Sequence: MSKDMLVNDGIRAREVRLIDQDGEQLGVKSKIDALQIAEKANLDLVLVAPTAKPPVARIMDYGKFRFEQQKKDKEARKNQKVIVMKEVRLSPTIDEHDFDTKLRNARKFLEKGDKVKCSIRFKGRAITHKEIGQKVLDRFAKACEDLCTIEQRPKMDGRSMFLVLAPLHEK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_SARHA
Sequence: MINIRKTHPLMKIINHSFIDLPTPSNISAWWNFGSLLGMCLIIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNHGWLLRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIITALVVVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGFMLLLLTLLILALFSPDSLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPLLHTSNQRSMMFRPISQTLFWILTANLITLTWIGGQPVEQPFIIIGQLASVLYFLLILVLMPLAGLFENYMLKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PDXA_BACTN
Sequence: MEENKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPKVAAYHRKALDVQANFSIVNTASEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALERAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGNKSLMILMKNDFRVALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLGMEEQEIIIPAMKEMEEKGIICYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAMEDGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAIYVAIDVFRNRQREKAARVNPLRKQYYEKRDDSDKLKLDTVDED
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS8_BOVIN
Sequence: MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 8, 26S proteasome AAA-ATPase subunit RPT6, Proteasome 26S subunit ATPase 5, Proteasome subunit p45, p45/SUG.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y3713_POLSJ
Sequence: MLFLLSPAKSLDYDTPPHVSTYTKPLFTRQSAELIDVLQTKTPQQISTLMKLSDALSGLNVARYQAWSPKFTAKNSKQAVLAFNGDVYGGLDAKTLSEQQLGWAQEHVCILSGLYGVLRPLDWMQPYRLEMGTALATGQGKNLYQFWGSQIADYLNQRAAAHTSPVIVNLASEEYFKAVDRKALKARVVSCVFEEFRAGKYKIISFMAKRARGLMVRYATEHKLLTVRKLEGFDAEGYRFDPAASQADRLVFRRRQAA
What are the official names of this protein?
UPF0246 protein Bpro_3713.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: YPE3_RHORU
Sequence: MNVKGTPTRTIWPAREGGAVWIIDQTRLPHEFVTQRLNDLGAVAHAIRAMLVRGAPLIGATAAYGVALGMAEDPSDEGLTRACQTLLATRPTAVNLRWAIEAMAESLAAVPPDQRAQAAWAKAGAICDEDVALNEAIGDHGLGIIKDLARTKGVEKGGEGPINILTHCNAGWLATVDWARPWRR
What are the official names of this protein?
Uncharacterized protein in petC 3'region.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: RUTE_ECODH
Sequence: MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFTGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: ISPF_GEOTN
Sequence: MFRIGQGFDVHQFVEGRPLIIGGVHIPYEKGLLGHSDADVLLHAVADACLGAIGAGDIGRHFPDTDPRYKDADSAELLAHVWSLVRQEGYVLVNADCTIIAQKPKMAPYIEEMKKVIARLLEAERSQVNVKATTTEKLGFTGREEGVAAQVVVLLQKSEA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.