PharMolix/UniProtQA huggingface dataset:
Protein: SBNO2_MOUSE
Sequence: MLAVEPTMDGDFPPHELPPPGGGIQLQNRLLHCPWWGSFSPSLYPTFSSENQQFVGSTPFLGGQSCPETSYPTTATVPSFFSKSSDFPQDPSCLEDLSNASVFSSSVDSLSDIPDTPDFLQADSLNEVPTIWDVSTTSTTHDKLFIPSGPFSAPEDPVTSLSSTPLLISYQSHSQPEEEEGEEEEETEELGHAETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLALPTSDNSTLSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGIIVENYLRGRKKALWFSASNDLKYDAERDLRDIEAPGIAVHALSKIKYGDNTTSEGVLFATYSALIGESQAGGQHRTRLRQILQWCGEGFDGVIVFDECHKAKNASSTKMGKAVLDLQSKLPQARVVYASATGASEPRNMIYMSRLGIWGEGTPFRTFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLSPAFQQVYNRAARLWAEALSVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVHRLVELAQQELSRDKCVVIGLQSTGEARTREVLDENEGRLDCFVSAAEGVFLSLIQKHFPSTRRRRDRGGGKRKRRPRGRGPKASRLSLEAAGVIRISDGSSTESDAGLDSDFNSSPESLVDDDVVIVDAPTHPTDDRGSLYPLQRDLQGPGVVERVERLKQGLLAKVRALGRELPVNTLDQLIHQLGGPECVAEMTGRKGRVVSRPDGTVVFESRAEQGLSIDHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENKYGARALSRVLATIMGQTDNRVPLPQGYPGGDTAFFRDMKQGLLSVGIGSRESRSGCLDVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEIDKKEGRYDMGILDLAPGINEIHEESQQVFLAPGHPQDGQVVFYKQISVDRGMKWEEALTRSLELKGPYDGFYLSYKVRGSKMSCLLAEQNRGEYFTVYKPNIGRQSQLETLDSLCRKFHRVTVEEAREPWESSYALSLEHCSHTTWNQRCRLTQEGKCCAQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDKKKQVGIKIPEGCVHRVLQELQLMDAEVKRRSTHGLAARPPTPRAITLPCGPGEVLDLTYSPPAEAFPTPPRFAFPSLPPPDPSSLMLGARDPATNPVELAHQSCDINFREVLEDMLRSLRAGPTETPAPLVGVGGGGTERQSVIHFSPPFPNS
What is the function of this protein?
Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions (PubMed:18025162, PubMed:23980096).  Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast (PubMed:23980096).  Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway (PubMed:23980096).  May also be required in the regulation of osteoblast differentiation (PubMed:23980096).  Involved in the transcriptional corepression of NF-kappaB in macrophages.  Plays a role as a regulator in the pro-inflammatory cascade (By similarity).
What are the official names of this protein?
Protein strawberry notch homolog 2.
What is the protein family that this protein belongs to?
Belongs to the SBNO family.
Protein: CD123_YEAS7
Sequence: MSSQEYTTFIDIPVTRAQVEHCSYSFWSSLYPKYVPKSIVLKSLPKKFIQYLEQDGIKLPQEENSRSVYTEEIIRNEDNDYSDWEDDEDTATEFVQEVEPLIDFPELHQKLKDALNELGAVAPKLNWSAPRDATWILPNNTMKCNEVNELYLLLNASNYIMHDLQRAFKGCVDGDDIKGLKFDLVLRQWCDMNPALEFRVFVKNAHIVGATQRDLNYYDYLDELSDTFKDLIDEIVHDVVLPKFPDKSFVLDVYIPRPFNKIFIVDINPFARKTDSLLFSWNEIAAIAPPKNDVEDYELRLVTRHNTGRFASKEHSENHVPQDLVEASLNPEAIRELTQKWKELLSQQAKEESSDSESET
What is the function of this protein?
Regulates the cell cycle in a nutrient dependent manner.  Accumulates in presence of nutrients and directs the destabilization of DMA1 and DMA2, whose accumulation results in a G1 block.  Regulates also the abundance of GCD11 an essential component of the translational initiation factor 2 (By similarity).
What are the official names of this protein?
Cell division cycle protein 123.
What is the protein family that this protein belongs to?
Belongs to the CDC123 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_ECOLI
Sequence: MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAAMLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
What is the function of this protein?
Could have an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: RL18_STRP8
Sequence: MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DAPA_STRM5
Sequence: MSLSGLITALATPFRADGALDPDGWQRLLHLQLEGGVHGVVVAGSTGEAATLTDAEYDQLLASAVERIGGRIPVMAGTGLSGTAKTIEQTRRAAALGASHALVVTPPYVRPTQAGLIAHYRAVADQGGLPVVLYNVPGRTGCDMQPETVAELASHPNIVGIKEAVGDTGRVQALLALRSAQFAVLSGDDGTAARSIRAGIDGLISVGSNVLPGAYRRMCELAAAHDHEATESWDGRLQPFHEFCGVEPNPIPVKALLRRIGIGHDLRLPLLPLSAVHHPAADHLAGDIAALEALSSH
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM2_MAIZE
Sequence: MALRTLASKNALSFALGGAARPSAASARGVTTVALPDLSYDFGALEPVISGEIMRLHHQKHHATYVVNYNKALEQLDAVVVKGDASAVVQLQGAIKFNGGGHFNHSIFWENLKPISEGGEPPHGKLGWAIDEDFGSFEALVKRMNAEGAALQGSGWVWLALDKEPKKLSVETTANQDPLVTKGASLVPLLGIDVWEHAYYLQYKNVRPDYLNNIWKVMNWKYAGEVYENVLA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 3.2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: IKKA_DANRE
Sequence: MEKPPFRQNQVCGSWVMKERLGTGGFGHVYLYQNQETSEKIAVKLCRLELNSKNKDRWSRGIQIMKKLKHLNVVTAKDVPEEMMHIALNDLPLLAMEYCSKGDLRKLLSKPENCCGLKESEVLSLLNDVGSGIQYLHENKIIHRDLKPENIVLQEINGKLVHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFEGKSYTVTVDFWSFGTMIFECCCGFRPFLHNLQPVQWTSKVRNKGPKDIMAVEDMNGEVRFSTHLPYPNNLSRTLLEPLEGLLQLMLKWDPVQRGLGLNTDSKQPQCFVLLDQILSMKVVHILNMTTTQVHSFLLSPDEGLHSLQQRIENETKIELLNQDLLQETGVMSDPRKPAAQCVLDGVRGWDSYIVYLFDKSLTKYMGPLTARTLPESVNFIVRETKTQLPLSTLKKVWGEAVSYICGLREDYSRLFQGQRAAMLSLLRFNTNLTRYKNMMFSFSQQLKAKLDFFKTSIQYDLEKYSDQMQYGISSEKMLKAWHENEERAAAFAQVAEIGHLDEEIMALHSEIVELQRSPYARRQGDVMEQLQEKAIELYKQLKAKCKMPDPQHGYSDSSEMVKVIVQTVQNQDRVLRDLYAHLSKILLSKQKIIDLFPKIERTLECIKEADTTVMQMQIKRQREFWHLLKIACAQNTTRSSVSQSGEMPSSLSTWNQTQAQCSSRLPMSLQVPHEGDSVNHLLEENQRYLTQLTSLLQETTEEKSESIMAQDWSWTKYESLVAKSPRL
What is the function of this protein?
Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor.  Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines.
What are the official names of this protein?
Inhibitor of nuclear factor kappa-B kinase subunit alpha, I kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, IKK1, Nuclear factor NF-kappa-B inhibitor kinase alpha, NFKBIKA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus.
Protein: TCTP_XENLA
Sequence: MIIYKDCITEDEMFSDIYKIIETPDGMCLEVEGKVIQREEGAIDDALIGGNASAEFQEDDVGGSSLTSGVDIVMNHKLQETGFTKDSYKNYIKDYVKQLKAHLEKTNPERVNTFMKGAQETVKKILGNFKNYQFYTGERMNPDGMVGLLDYREDGITPFMIFFKDGLIIEKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_HELPY
Sequence: MNETLKEELLQSIREVKDYPKKGILFKDITTLLNYPKLFNKLIDTLKKRYLALNIDFIVGIEARGFILGSALAYALGVGFVPVRKKGKLPAHTLSQSYSLEYGSDSIEIHSDAFRGIKGVRVVLIDDLLATGGTALASLELIKALQAECIEACFLIGLKELPGIQLLEERVKTFCLLEC
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_CMVKO
Sequence: MDKSESTSAGRNRRRRLRRGSRSAPSSSDANFRVLSQQLSRLNKTLSAGRPTINHPTFVGTERCKPGYTFTSITSKPPKIDRGSYYGKRLLLPDSVTEYDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVPAISAMFPDGPSPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYAKDDALATDELVLHVDVEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: TSAD_VARPS
Sequence: MLLLGIESSCDETGVALVETHGSALPQLRSHALHSQIAMHQAYGGVVPELASRDHIRRVLPLTEAVMAEAGRSLAEIDVVAYTRGPGLAGALLVGAGVACALGAALGKPVLGVHHLEGHLLSPFLSADPPEFPFVALLVSGGHTQLMRVDGVGRYELLGETIDDAAGEAFDKSAKLMGLPYPGGPWLAKLAEAGNPAAFKLPRPLLHSGDLDFSFAGLKTAVLTQAKKLGAELEANKADLAASTQAAIVEVLLKKSLAALGQTGLKRLVVAGGVGANRSLREQLNAACAKRGVRVHYPELHLCTDNGAMIAMAAAMRLQSGLAEASERYAFDVKPRWPMASLMASSAAPVAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_SACEN
Sequence: MMRTHEAGSLRAGHAGQSVTLAGWVARRRDHGGVIFIDLRDASGVAQVVFREGEMAERAHRLRSEFCLRITGEVVRRPEGNENPEIGTGDIEVTATELEVLSESAPLPFPLDEHLEVGEETRLRHRYLDLRRNGPAKAMRMRSEVNRIARDVLHGRDFVEVETPTMTRSTPEGARDFLIPARLQPGNWYALPQSPQLFKQLLMVGGLERYFQIARCYRDEDFRADRQPEFTQLDIEMSFVDQDDVIELGEEIISALWRETAGHEIPRPIQRMTYADAMARFGTDKPDLRFGLELTEMTEYFADTPFRVFRAPYVGAVVMPGGADQPRRQLDAWQDWAKQRGAKGLAYVLVGQDGTLSGPVAKNLSDGERDGLVKAVGAAPGDCVFFAAGDRSSSRALLGAARLEIGERCGLIDHDAWSFVWVVDAPMFESIDDTDDVAVGSGRWTAVHHPFTSPNADWVDNFESDPANALAWAYDIVCNGNEIGGGSIRIHRSDVQKRVFELLGISEEQAQDKFGFLLEAFKYGPPPHGGIAFGWDRICMLLAGADSLRDVIAFPKSGGGYDPLTGAPSPITVEQRKEAGVDAKPAAKVGDESISVFPPGVVEKQG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ1_OPITP
Sequence: MTPVEAQSRIAELRAQVARHDELYHRRAQPQIGDFEYDALKRELAELEAAWPQFARGASPTEQVGDDRTEGFQVYRHRERMMSLDNTYSETELREFHDRLVRELERDGLKFVIEPKIDGLAVSITYEKGKLVRAVTRGNGIEGDDITTNALTIKSLPRELKRADGVPLPAVIEIRGEVFLTTEEFLRINRQREEAGEPLYANPRNLAAGTIKQLDPREVAQRKLEVVLYGRGYVEPASALPETQAQFHGWVKAWGLPTVERFWTATGADEIWAAVQELDALRDTFAYATDGAVVKLDAVPLQRRAGSTSKSPRWAMAYKFAPDRAETQLRAITVQVGRTGVLTPVAELDPVQLAGTTVSRATLHNRDEIARKDIRVGDFVYVEKAGEIIPAVIGVNPARRAPECVPYVFPEKCPECGTAVVQLEGEVAVRCPNFSCPVQVRRRVQHFASKACVDIEGMGEAMVDVLVEKGWVHSVPDIYQLKRENLLTLGKSVEKSTDKLLEAIEASKRAELWRFIHGLGIPHAGAAAAKDLARTFGGLERLASARYEDFIREKASVIGGIGETMALAILAYFAEPRNRAVVDELVRVGVQPVVPNSGSALAGKTFVLTGTLPTLTRDEATAQIEAAGGKVSSGVSKKTSYVLAGEEAGSKLEKARALAVPVIDEAEFLRLLSGG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase 1, Polydeoxyribonucleotide synthase [NAD(+)] 1.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: IRX9L_ORYSJ
Sequence: MSRRNAGAMQREGSVKDWEEFDPSPSPKLAYSQSYVAMRGLLTSVASLDLVLMSSSLKSAWAAISSHKHARSLERSRSKGMSLKRAMLQLLVCFMVGIFIGFTPPFSVDLPGKIASENGRLPFDGDAIDRRQMVERQGTKLEPFVAEAESEASSEPQVEEGPPVPAMLDDEADFVEASPIVHSVNDSGIVVRKHLIIITTTSVRPHQAYYLNRLAHVLKDVPPPLLWIVAEWPYQSRETAEILRSSGIMYRHLICNRNTTNIRKIVVCQKNNAIFHIKKHRLDGIVHFADEERAYSADLFEEMRKIRRFGTWPVAIHVGTKYRVVLEGPVCKGNQVTGWHTNQRRGVSRRFPIGFSGFAFNSTILWDPQRWNSPTLESIIVHSGGRGGLQESRFIEKLVEDESQMEGLGDNCTRVMVWNFELEPPQVNYPIGWLLQRNLDAVVPIT
What is the function of this protein?
Probable beta-1,4-xylosyltransferase involved in xylan biosynthesis in cell walls.
What are the official names of this protein?
Probable beta-1,4-xylosyltransferase IRX9L, OsGT43F, Probable glucuronosyltransferase Os01g0675500, Protein IRREGULAR XYLEM 9 homolog L, OsIRX9L.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RS4_SALEP
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTYKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CTR2_OCTVU
Sequence: MYQAMEVESTSPSGFFLDFYTQSTIPTTDFLNNTNSSHPIRDEKLVKIEIAVLGTCFTLAIINNLCVLLVLLWRRKKVRRMQMFILHLSIADLIVAFFNILPQLIWDITFRFMAGDAMCRFIKYAQMFSLYLSTYILIMTAVDRYRAICHPLSNQTWTPCMVYCKIFIAYAIATIFSIPQAILFQMQEVNEGSGIYDCWVHFEPAWVLTAYALYIFFALYLIPILILFFTYGSICYTIWAKYRHAIKTKKDANTRYPQRRKKKGVILRTHSVHGFSKAKLNSVKLTFAVIVTYIICWSPFFVSQIWWLFDETVVGNAGVVVILLMACLNSCTNPWIYLIFNRNYISNVLPCKCLRRHRVEVAATTETERLSLGSVRRDSRKTSDPKRISESRRISDARRISGKTQKNNSSSPRKTSDQFIYSDKTT
What is the function of this protein?
Acts as a receptor for cephalotocin.
What are the official names of this protein?
Cephalotocin receptor 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SDHD_BACSU
Sequence: MSVHSEVLHALLKDPFIQKLIDAEPVFWANSGKKEGPLPRADEWATEIAEAEKRMQRFAPYIAEVFPETKGAKGIIESPLFEVQHMKGKLEAAYQQPFPGRWLLKCDHELPISGSIKARGGIYEVLKYAENLALQEGMLQETDDYRILQEERFTGFFSRYSIAVGSTGNLGLSIGIIGAALGFRVTVHMSADAKQWKKDLLRQKGVTVMEYETDYSEAVNEGRRQAEQDPFCYFIDDEHSRQLFLGYAVAASRLKTQLDCMNIKPSLETPLFVYLPCGVGGGPGGVAFGLKLLYGDDVHVFFAEPTHSPCMLLGLYSGLHEKISVQDIGLDNQTAADGLAVGRPSGFVGKLIEPLLSGCYTVEDNTLYTLLHMLAVSEDKYLEPSALAGMFGPVQLFSTEEGRRYAQKYKMEHAVHVVWGTGGSMVPKDEMAAYNRIGADLLKKRNEK
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: RNH2_TRIV2
Sequence: MMLKKAQTTDNLKLPISLNATGWLESSPDWSNISGLVAGVDEVGRGALFGPVVAASVILPASSFPQLMTAEIKDSKKLSHSRRVQLAQQISTLAIDWRIGYATTAEIDRINILQATLLAMRRSVKKLKLQPILCLVDGNQPVQDLPILQQTIVKGDERSLNIAAASIMAKVWRDDLIQRLSTKYPMYDLKSNKGYGSKKHLLALEKHGASPLHRQSFRPCQISLD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG10_MOUSE
Sequence: MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKECSDGYMCKTQFRIKNEASTPHVGTPASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE
What is the function of this protein?
E2-like enzyme involved in autophagy.  Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5.  ATG12 conjugation to ATG5 is required for autophagy.  Likely serves as an ATG5-recognition molecule.  Not involved in ATG12 conjugation to ATG3.  Plays a role in adenovirus-mediated cell lysis.
What are the official names of this protein?
Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10, APG10-like, mAPG10.
What is the protein family that this protein belongs to?
Belongs to the ATG10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_COLP3
Sequence: MSRFFRRRKFCRFTAEGATSIDYKDIATLKNYITESGKIVPSRITGTAAKYQRQLTRAIKRARYLSLLPYTDLHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GLHA_PANTA
Sequence: MDYYRKYAAVILAILSVFLHILHSFPDGEFTMQGCPECKLKENKYFSKLGAPVYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNAKVENHTECHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCIB_BRUA2
Sequence: MEHPVFERDPSEKSETERREVPPLLKLALELGPLLVFFFANARGEMLIERFPILGSIGAPIFLATALFMAATVIALAISWSMTRTLPIMPLVSGIVVLVFGALTLWLHNDTFIKMKPTIVNTLFGGILLGGLFFGKSLLGYVFDSAFRLDAEGWRKLTLRWGLFFIFLAIVNEIVWRNFSTDTWVSFKVWGIMPITIVFTLLQMPLIQKHSLTDEENTAS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOD_RHORT
Sequence: MAQTEIKSYTLNFGPQHPAAHGVLRLVLELSGEVIERADPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYACPMNQEHAYVLAVEKLLGITVPPRAQYLRTLFNEVTRLINHIMNTTSMALDIGAMTPLLYGFEEREHLLEFSERASGARMHAAWFRPGGVARDVPPDLLEDILKFCDSFPKYLDDVEHLLDENRIFKQRTVDIGKVTAQQALDWGFTGPVLRGCGVPWDLRKSQPYDAYAAMDFDIPTGANGDCYDRYLVRMAEQRQSIRIMRQCIEKMPDGPVKAVDHKVTPPSRGEMKSSMEALIHHFKLFTEGFKVPEGETYTAVEAATGEFGVYLVSDGTNRPYRCKIRSPGYVHLQGLDLMSRGHMLADVVANIGSIDVVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARGJ_PODAN
Sequence: MVGFSRCALSQLRQPKAQLVRSFSHIPSRAYSAPSSSIPAAKKKYIPTSGTYPLGFQVSGTIVGVKPSNTTKPDLALLTSEVPCAAAAVFTKNKFQAAPVTFSRALLQKKGNKGIQGVVINSGCANAVTGKGGLEDAAKMAQAADKCLGQSDSIIVMSTGVIGQRLPIDKIINNVPKAHSALGGSHEHWLTMAKAICTTDTFPKLISRTFTLPSSPGVEYRIAGTTKGAGMIHPNMATLLGVIATDAPISSSALPSVLKHAVDRSFNSITIDGDTSTNDTVALLANGMAGGKEVVEGTPDYEAFREVLTKFSTELAQLIVRDGEGATKFVTIKVVDSASEEAARKIASTIARSPLVKTALYGKDANWGRILCATGYSLISEPSEPINDVPEIVPENTNVSFVPTDGTAELKLLVNGEPEQVDEARAAEILELEDLEILVRLGTGDKQATYWTCDYSHEYITINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GLDS1_YEAST
Sequence: MALANSRPLQIPTLENEILHNSNSPVFQLNSMGFTTRADTISNPGTDLIGNQPGMALDDNNLAGSSFSSSQEIKATKPKKDFGAPKKDNPLLEISKLIPVTGERPKPENRDSPLDDDVLHAVFLILWEMDPNQQGMTVKQLCDLLLQKHPDMSNLSTKLSNLISAKLNAYVKKIEKGEKTLTYALSREWSNSSPRRMLYIYRGILSPDYKEHAQAVTMQLKQQLETSGDTSDFNSNGKKKRESSSNQLVNNDSYSSSMTDMKNMSSNSSFSKNLNVGNLAFSLSPEFNIPYSTSPVSLNLSPSMSNNQQQLLTPNSASKSKNNNKKRNYMDEDTNESMTEPKKTKTTKPGKQTKSQSLSVLSTPKKGSSASLSTFASSKNISPDSSLSHNASSNTYVTAAAAAPRLSKLLPKNGFKKNSRSSSELAAIHKVISTQTPIESSSESSQYNSSSSSPVNSAAASSAESLSDINSSQDNGRESNPSSQESRNEVTNWMKIVRNGFLTHDIESPESITLDDLENIFN
What is the function of this protein?
Involved in nuclear control of mitochondria.
What are the official names of this protein?
Protein GDS1.
Protein: SOTB_PSEU2
Sequence: MITSPPNEQAGSWLGVFALALAAFIFNTTEFVPIGLLSNIGQSFEMTPAQVGLMLTIYAWVVSLMSLPMMLATRNIERRKLLMFVFGLFVVSHVLSAIAPSFAILLVSRVGIAFAHAVFWSVTASLAVRIAPPGKQVQALGLLATGTSLAMVLGIPLGRVLGEALGWRTTFLGIAAIAALVVFLLVRALPLLPSQNSGSLRSLPILFKRPRLMAIYLLTAIVVTAHFTAYSYIEPFTQTVSLLSGEMTTILLLVFGGAGIMGSIIFSLFSDRFPNGLLITAIGTLTLCLLMLLPLSGDAVTLGTLTIIWGMAIMCFGLTLQARVLSLAPDATDVAMALFSGIFNIGIGGGALLGSVVSSHLGVANVGIVGGLLALGGLGLCCYTTHHFGKVRPAAEMQAESK
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y6575_BACAN
Sequence: MEEIKCLLCRYLKERQEKFISDWKKKVIIRERDPYKEEIIKNGEHLLSAFIMYLKEEISLQEIEITSKKIARERIDAKVNIAEFIHNTNVAKIEIMNILTLLNPDLQQYQALVKKINQFFDHLIYYTVHSYYEQKA
What are the official names of this protein?
Uncharacterized protein pXO2-61/BXB0075/GBAA_pXO2_0075.