PharMolix/UniProtQA huggingface dataset:
Protein: YKY4_SCHPO
Sequence: MVKLSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGKIVLTSDTIQQWQKLLETNHSLTTLQKVVQAFKAAAFLNEEEAEDLKYTISDSKVFNDLLLLAIQYVPKVLNYHVPIQEDAKGKKFINTDSKVLPKLRPVLKSYGFSILRLLEGMTDAKNISLLLREAQNVLPYMITYRKFLKQFTQATVEVWSSTRDDSVRFSAVVLLRTLCLTADITLLEFVLKEVYLGMARQSAYTTVHTLDKINFLKNSAVNLFLLDAESCYLIGFRYIRQLAITLRNTIHQPSKDSRKPVQSWSYVHSLDFWARLLSQAAWLSREKGVASELQSLVYPLVQIALGVIMSSPSSQLFPMRFHIIRSLIYLSRHTGVFIPLAPSLFEVLDSSYVSRKAKASTLKPLDFDVELRASSSYLRTKVYQDGLIDQLLELLSEYYVLYATDISFPELVIPAIVRSKRFAKRSKNAKLNRGLLTLVNRLEQQSKFMTEKRNQQKFAPIDSDSVEQFAQTIDWQQTPLGIYVVTQRQTREEQRKLIRESVQQDQEHKEQMRQKKKQALKSDDIELDDLSEEEAEDIDE
What are the official names of this protein?
Uncharacterized NOC2 family protein C1142.04.
What is the protein family that this protein belongs to?
Belongs to the NOC2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TTR2_CAEEL
Sequence: MSKYAILGLVLVGTVASLDFIGRTQSAAIKGRLVCEGKPASGVKVKLMESDNSFGPGFLDSDDKMASGKADSHGEFNLSGSTKEITGIEPYLVVFHDCKDGITPCQRVFRVNVPKSYTNSGSSAKKTYDAGVIELAGKYPGETRSCLN
What are the official names of this protein?
Transthyretin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the nematode transthyretin-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL1_RHOCB
Sequence: MAAKTYDAGVKDYRSIYWEPQYQVKDSDILAVFKVVPQPGVSREEAAAAVAAESSTATWTTVWTDLLTDLDYYKGRAYAIEDVPGSDEAFYAFIAYPMDLFEEGSVVNVFTSLVGNVFGFKAVRALRLEDVRFPLWFVMTCPGAPHGMKVERDLLDKYGRPLLGCTIKPKLGLAAKNYGRAVYECLRGGLDFTKDDENVNSQPFLRWRDRFLFCQEAIQKAEAETGERKGHYMNVTAGTMEEIYERAEFAKEIGTPIIMSDYLTVGWAAHTSLSRWCRKNGMLLHVHRAMHAVMDRNPNHGINFRVLAKILRLMGGDHLHSGTVVGKLEGDREATIGWINLLRDRFIKADRSRGIFFDQDWGPQPGLFPVASGGIHVWHMPALVSIFGNDSVLQFGGGTLGHPWGNAAGACANRVALEACVQARNEGRHLEKEGKEILTKAAQSSPELRMAMETWKEIKFEFDTVDKLDVQHR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: PSBF_ORYNI
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUOK_ENT38
Sequence: MIPLTHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQPDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSELRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPIS_XANCP
Sequence: MRRKIVAGNWKLHGTRAFATELVAQVAAHMPLAGVDVVILPPLPYLGDLIEDFEAHHLAFGAQDVSSNEKGAYTGEVSASMLVDVGAEYGLVGHSERRQYHQESSELVARKFAAAMHAGLIPVLCVGESLEQREAGQTEAILRAQLEPVLSLVGSAGFARAVVAYEPIWAIGTGRTATPDQAQAVHAFIRGEVAKADARIADSLPILYGGSVKPDNASELFSQPDVDGGLVGGASLVAEDFLAIARAAAAC
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPY_ALLMI
Sequence: YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
What is the function of this protein?
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
What are the official names of this protein?
Neuropeptide Y, NPY.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: PQBP1_MOUSE
Sequence: MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRIEGLPPSWYKVFDPSCGLPYYWNVETDLVSWLSPHDPNFVVTKSAKKVRNNNADAEDKSDRNLEKVDRNHEKSDRSHEKPDRSHEKADRNHEKNDRERERNYDKVDRERDRDRERERAFDKADREEGKDRRHHRREELAPYPKNKKATSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASRTKQQD
What is the function of this protein?
Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development (By similarity).  Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species (PubMed:23512658).  May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner (By similarity).  Can activate transcription directly or via association with the transcription machinery (By similarity).  May be involved in ATXN1 mutant-induced cell death (By similarity).  The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit (By similarity).  Involved in the assembly of cytoplasmic stress granule, possibly by participating in the transport of neuronal RNA granules (By similarity).  Also acts as an innate immune sensor of infection by retroviruses, by detecting the presence of reverse-transcribed DNA in the cytosol (By similarity).  Directly binds retroviral reverse-transcribed DNA in the cytosol and interacts with CGAS, leading to activate the cGAS-STING signaling pathway, triggering type-I interferon production (By similarity).
What are the official names of this protein?
Polyglutamine-binding protein 1, PQBP-1, 38 kDa nuclear protein containing a WW domain, Npw38, Polyglutamine tract-binding protein 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasmic granule. Note=Colocalizes with SRSF2 in nuclear speckles (PubMed:23512658). Colocalized with POU3F2. Colocalized with ATXN1 in nuclear inclusion bodies. Localizes to cytoplasmic stress granules (By similarity).
Protein: MPTA_METM5
Sequence: MQCNDVQATEPDIKVSLTRVGVTNLKKLVKLKRKNKRDIVLLPTFEVFVDLPSSQKGIHMSRSPEVIEEVVENILLEKEIYGVEDLSVEIVMKLFEKHEYATRAEIMLYSDYMMEEKSPVTQKDSQEIGKIIARAYGVKDENGKIAVKKMVGAEVVGITACPCAQNMLKENAVANLKEKGFSSEEIEKILDSVTIATHNQRGIGTVMIEVPNGYAVGISKIIKIIKNSMSGEVYELLKRSDEAFVVEAAHKNPKFVEDCAREMIKRVVDVFDYLPEDTQVLVRQVNKESIHRHDAFAERNSTIRELRDELKTLTN
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: ELOC_RAT
Sequence: MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
What is the function of this protein?
Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins.  This includes the von Hippel-Lindau ubiquitination complex CBC(VHL).  By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.  As part of a multisubunit ubiquitin ligase complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A (By similarity).  A number of ECS complexes (containing either KLHDC2, KLHDC3, KLHDC10, APPBP2, FEM1A, FEM1B or FEM1C as substrate-recognition component) are part of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (By similarity).  ECS(LRR1) ubiquitinates MCM7 and promotes CMG replisome disassembly by VCP and chromatin extraction during S-phase (By similarity).
What are the official names of this protein?
Elongin-C, EloC, Elongin 15 kDa subunit, RNA polymerase II transcription factor SIII subunit C, SIII p15, Stromal membrane-associated protein SMAP1B homolog, Transcription elongation factor B polypeptide 1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GXLT2_HUMAN
Sequence: MKLRSKAAALLLLALAALLLALLSLRAGRAEPPALPARPASAPQRHPAPVPARWPGPGALPGASPGVRRRRPPRPRPRAGRRGAARLEKLARRPGEPRSFQAVLPPELWIHLAVVACGNRLEETLVMLKSAVLFSHRKIQFHIFTEDSLKPEFDKQLRQWPDSYTKKFEHRIYPITFSVGNPQEWKKLFKPCAAQRLFLPVILKDVDSLLYVDTDVLFLRPVDDIWKLLRLFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRSTQFKNSMIPTGLAWEDMLYPLYQKYKNAITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCREAEHEGVSVLHGNRGVYHDDKQPTFRALYEAIRDFPFQDNLFQSMYYPLQLKFLETVHTLCGRIPQVFLKQIEKTMKRAYEKHVIIHVGPNQMH
What is the function of this protein?
Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.
What are the official names of this protein?
Glucoside xylosyltransferase 2, Glycosyltransferase 8 domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: OLA1_HUMAN
Sequence: MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK
What is the function of this protein?
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency.  Has lower affinity for GTP.
What are the official names of this protein?
Obg-like ATPase 1, DNA damage-regulated overexpressed in cancer 45, DOC45, GTP-binding protein 9.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
Protein: PGK_PSYWF
Sequence: MNFARMENQDLSGKTVLIREDLNVPVQNGKISNDARLQSSLPTIKLALEKGAAVLVCSHLGRPTEGDYEEKYSLQPVADYLSEHLNQPVRLDKTYTEQEVTVAPGDVVLLENVRFNVGEKKNSDSLSQHYADLCDVFVMDAFGTAHRAQASTEGVIQAAAKAGKVVCAGPLLAAELDALDKALHKPKKPLVAIVGGSKVSTKLDVLISLAKICDQIIVGGGIANTFIAAQGHSVGASLYEAEMIDTAKQIMQQTDILLPKNVVVADKNQINFDDFLNSLESATPIHRSIEQVGEDEMILDIASEGAEHIFEAVKNAATILWNGPVGVFEVEAFSEGTRLLSEAVKDSAGFSIAGGGDTLAAIHKFNVEDGVSYMSTGGGAFLEFVEGKTLPAVAALEANHSK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO1_MYCTO
Sequence: MVTTASAPSEDRAKPTLMLLDGNSLAFRAFYALPAENFKTRGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSRQTFRLQRYPEYKANRSSTPDEFAGQIDITKEVLGALGITVLSEPGFEADDLIATLATQAENEGYRVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQYPDFAALRGDPSDNLPGIPGVGEKTAAKWIAEYGSLRSLVDNVDAVRGKVGDALRANLASVVRNRELTDLVRDVPLAQTPDTLRLQPWDRDHIHRLFDDLEFRVLRDRLFDTLAAAGGPEVDEGFDVRGGALAPGTVRQWLAEHAGDGRRAGLTVVGTHLPHGGDATAMAVAAADGEGAYLDTATLTPDDDAALAAWLADPAKPKALHEAKAAVHDLAGRGWTLEGVTSDTALAAYLVRPGQRSFTLDDLSLRYLRRELRAETPQQQQLSLLDDDDTDAETIQTTILRARAVIDLADALDAELARIDSTALLGEMELPVQRVLAKMESAGIAVDLPMLTELQSQFGDQIRDAAEAAYGVIGKQINLGSPKQLQVVLFDELGMPKTKRTKTGYTTDADALQSLFDKTGHPFLQHLLAHRDVTRLKVTVDGLLQAVAADGRIHTTFNQTIAATGRLSSTEPNLQNIPIRTDAGRRIRDAFVVGDGYAELMTADYSQIEMRIMAHLSGDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRVKAMSYGLAYGLSAYGLSQQLKISTEEANEQMDAYFARFGGVRDYLRAVVERARKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVAMIQVDKALNEAQLASRMLLQVHDELLFEIAPGERERVEALVRDKMGGAYPLDVPLEVSVGYGRSWDAAAH
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: Y5755_PSEFS
Sequence: MKNVSPTYLKHQFLIAMPHMADPNFAQTLTYIVEHTAKGAMGLVINRPQELNLADILEQLRPEVDPPARCQGVPIYIGGPVQTDRGFVLHPTGPKFQATVDLEGVSLSTSQDVLFAIADGVGPEQSVITLGYAGWEAGQLEAELASNAWLTCPFDAEILFNTPSELRLEAAAAKLRVNLNLLTSQAGHA
What are the official names of this protein?
UPF0301 protein PFLU_5755.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MU137_SCHPO
Sequence: MVSRFFSWTNEKPLGDQRAHLPDSFLELEQEIAIREEGLSKLFQATTIWIDSILKKVDGEDKEKCLACENLGKVMINHSKELPQDSSYGITLSQLGKANLKIGEHQTSLAYKARVCYLDFLKRYLVQAKDFHSARKKLESRRQAYESLLQKSFKEKKEDSRLEEDIRLALYKFEESTEQVKNRMIALKDVEADQYQQLTELIVYELNFFKESTGILNTIFNSQNSLTPQKKIQSSERSVENEFLASPMDPSLSKLFTKTTNTEKISPTPFSTPKRKSKKETVFVKAIYSFTGRNEKELDLHTGDVIQVSEQLGPDWYMGEKVNSKAEKLGNSGMFPVNYCTRIYDLHVQKSHETRSLERARSIRRIVSDDPRDYCSPIKQSPIQNLKFLDSDNSLLSSQNVEASSQPIKIRKPLPEIPNK
What is the function of this protein?
Has a role in meiosis and sporulation.
What are the official names of this protein?
Meiotically up-regulated gene 137 protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at the barrier septum.
Protein: GUAC_ALKCK
Sequence: MMENVFDYEDIQLIPAKCIVGSRAECDTSVELGGRTFKLPVVPANMQTIIDENIARYLAENDYFYIMHRFQPETRLAFVKDMHERGLYASISVGVKEEEYTFVQQLADQHVVPEYVTIDIAHGHSEAVINMIRHIKTHLPDSFVIAGNVGTPEAVRELEHAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTHGDIAKSVRFGATMVMIGSLFAGHEESPGDTIEKDGKLYKEYFGSASEYQKGERKNVEGKKMYVEHKGSLAETLLEMEQDLQSSISYAGGKRLDAIRNVDYVVVKNSIFNGDKIY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: XPOT_CANGA
Sequence: MLARIREVVSIANGSTSSDPESKRQAIEYFEQLKNDVQSTEIFVSLMTDEGSDDLMRFVALQVVCEQIGNGILSQAQLTFVRNAAIELLRSKVNVPNGNLKSTPEYIRTKIAELVTRLFYVLYQDQWQSFFPDLTEILQIQSLLENPNENFSLIGIDYFCRICVFINSEIADQTFVRSKEIQQKNNDLKDQMRVQDVQRLVTIWINTLKSIAPNKQPDIAIMIMACIGSYISWIDVTLIVVPEYVSLIINYLEFPETKISCAQCLCEIISKKMKPVDKLSLLSLLDLTTKVASFDNSVDDVDISEQLARLASAVGTELTIILEQCNEANPPTEESQQLFSAADQQILLQVIPLILKFMLHEYDSVTQQSFQFISQYLAVMKKMFAVGGKAGSVVAVNSKRQSLDSAHEEFLVSLLQVCFKKMKIDESCTEESVDDIEVFCESIRSKLKVFQDTVAVINPQIFLTNISACIQNLINSADWRDIELVIYQLHNLSESIRNNLFGLPKNQIINSEPSMIMNNFMRLLLDNSTVFQMDSSYVQISFFELIVRHYQFLSFSGTKDELSLLNIFCSPFGMFNKREKTRLRTWYLFSRLLKTTKPKFPISVLNEIVGKIAPLLPIKVYSLNNDGVEEDSIFESQLYLFEGLGVLIGGNTDSNFEILNEILTPLFTDLEACISSSQEQPQVVLQCHHILLAIGTLARAVHSGLVPENRVNNALVSKKLIHRSLIEKFMNIAEVVLVTFSYFSKHETIRDASRFTFSRLIPILSDDIVPFANKLILLYLESNLKMMEMSDFLSFLGQMIHMFHKEQSCFELFNNLLGPVISKVHVLMTQIEQERNGEENPEWNGTTLNKGHGSNGKNIIITDAFRDKMLLKKAYMGFLQSFVTNNVTSLLLTTQGREVLPTILNDVLEYTPQEIQELSVMKLSLNVLVNFVKFFGSGKCTDPEDMYAASIEKLDGLNEFFITKVIPLVFEIPFKPEYKFNVREGSCRVIASDLSRLLLELYLQSGGGTSIDTNPCLKYLTEVYLPMVQFPPELIMDLVQNLITSNPKSFEKYFVQLITNFTA
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: CCA_LACDB
Sequence: MTNIRITEVFTQAMPVLEKLEEAGFEAYFVGGCVRDLLLERPIHDVDIATSAYPEEVKETFAKSIDTGILHGTVTVLYGGSSYEITTFRTESGYQDFRRPDKVTFVQNLDEDLKRRDFTINALAMNRQGEIIDLFDGLGDLKRRVIKAVGVAEDRFHEDALRMMRAVRFMSQLSFSLEEKTRQAIINNHELLSKISVERIREEFVKLALGKDSRQAFKDFLATGLSEECPGLAGKKDQLSVLTDLKAGPDDEAVFWSLIAVLINLPADKISPFMRAWKNSNAMNQQVRQIVAAFDLLSRGEESDFDLFEIGQENLEAALKLAGLLGKPLSSQVLLDRYNRLPIKAAGELAIDGQWLIKEGIKPSPELGQLLRKALEGVVSGQVENSQAAIAEFLAI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: H2A_CAEEL
Sequence: MSGRGKGGKAKTGGKAKSRSSRAGLQFPVGRLHRILRKGNYAQRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLPKKTGGDKE
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS30_CRIGR
Sequence: KVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS
What are the official names of this protein?
40S ribosomal protein S30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS30 family.
Protein: RS14_CHLAB
Sequence: MAKKSAVARENKRRKLVEANYKKRSELRKIAKSLTASEEEKENARVALNKMKRDTAPIRLHNRCLLTGRPRGYLRKFAISRICFRQMASMGEIPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RIMM_GLOVI
Sequence: MQQWLEIGKVVAAQGLRGEVRVQPATDFAERLTRPGARLVGRSLDDGRVFRLQSGRAIPGKDLFVCRFEGVEERNAAEKLVGSTLWIGAAERPVLAAGEFWLPDLMGVRVFRQDTGEAIGEVSDMTRAGNDLLVIRLSGGKTVMVPFVHALVPVVDLEAGRIEVVAIPGLLDPEAAEADEA
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STREQ
Sequence: MKLQKPKGTQDILSVAAAKWQYVEGVARETFKQYHYGEIRTPMFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKGVTLHLNSLGNAASRAAYRQALIDYLSPMRDTLSKDSQRRLDENPLRVLDSKEKEDKIAVANAPSILDYQDEESQAHFDAVRSMLEALAIPYVIDTNMVRGLDYYNHTIFEFITEVDQSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIAVLGADANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADTFKAKVVITLGESEIKAGQAVLKHNQTRQEMTVSFDQIQTDFASIFAECVQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPID_SCHPO
Sequence: MSTYAYFKISIDGKIQPTIYFELFDNVVPKTVKNFASLCNGFEKDGRCLTYKGSRFHRVIKNFMLQGGDFTRGNGTGGESIYGEKFEDENFELKHDKPFLLSMANAGPNTNGSQFFITTVPTPHLDGKHVVFGKVIQGKSTVRTIENLETKNDDPVVPVVIEECGTCTKDQIEAPKPDVTGDSLEEFPDDYEGDKSETAIFKIASDLKGIANKQFAQQNLDTAVAKWQKALRYLMEYPVPNDDSKESPDFWKEYNALRYSIYANLALVALKQNKPQEAIRNANIVIEASNSTELEKQKAYYRLGCAQGLLKNFEESEKALAKAGNDPAISKKLAEIRQKKKDYKKRQQKAYAKMFQ
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
40 kDa peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin-40, CYP-40, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPMT_SHEB2
Sequence: MEPGFWHEKWHQQQIGFHQQDINPFLVKYWQKLGLPADTQVFVPLCGKSLDMCFLAEQGHQVIGCELNELAVQQFFSDNQLEMTQTTVGEHQHYHTEQISLYQGDIFTLPKTITQAVTAFYDRAALIAWPESMRAQYAKQLASLLPSGSVGLLVTLDYPQEALIGPPFAVSPTWVEQHLSDDFDIEVLASQDVLADNPRFIKKAVPWLNEAAYLLKRK
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_BRUA4
Sequence: MSLIDTRIPEPKRFISGATGDWEVVIGMEVHAQVTSESKLFSGASTSFGAEPNSNVSLVDAAMPGMLPVINLECVKQAVRTGIGLNAQINLKSVFDRKNYFYPDLPQGYQISQFKQPIVGEGKIMISVGPDNKGQFEDVEIGIERLHLEQDAGKSMHDQHPTMSYVDLNRSGVALMEIVSKPDLRSSDEARAYLTKLRTIVRYLGTCDGNMDEGSMRADVNVSVRRPGGEFGTRCEIKNVNSIRFVGQAIEYEARRQIAILEDGGSIDQETRLFDPVKGETRSMRSKEEAHDYRYFPDPDLLPLEFDQAFVDALAVDLPELPDVKKQRLVEKQGISIYDASILVTEKAIADYYESVAAGRDGKAAANWVINDLLGALNKAGKDIEESPVSPEQLGAVIDLIKEGTISGKIAKDLFEIVWNEGGDPKKLVEERGMKQVTDTGAIEKAVDDVIAANPEKVEQAKAKPTLAGWFVGQVMKATGGKANPQSVNELVKAKLGIEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.