PharMolix/UniProtQA huggingface dataset:
Protein: BTPSL_METMF
Sequence: MEKQRLKAQLSSLRVPLFSVPWPGQCSNKAEVIEARMMKWADEHNLLVTDEYRNRVIRTRYGLLAARCYPNAGEVLLQAIADYLVWFFLADDLFVDRVEVATDETIRNLTAMVDVLDLNVAGSPPVFGELAWLDVCQRLRRLLQAEAFERFAQGMRLWATTAALQILNHLRPTPVGIREYQTIRRHTSGLNPCTSLADAANKGSVQACEFYDADVQTLVRQTNNIVCWANDIQSLRIEIHQPGQFRNMVTIYAQQGQSLQDAVETTATRVNKEIAGFCELADAVTARPISDELHGLIDGLEYWIRGYLDWVVHDTMRYADQFIESDADDRRFSAPDLSLLKKNCSSVTESTSSLV
What is the function of this protein?
Terpene synthase that catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into sesquiterpenes which are important for fungi-environment interactions (PubMed:31239482).  Produces a mixture consisting of 8 sesquiterpenes including corvol ethers A and B, as well as traces of epizonarene, gamma-cadinene, delta-cadinene, alpha-cadinene, alpha-cadinol, and an unidentified sesquiterpene (PubMed:31239482).  The major product is corvol ether A (PubMed:31239482).
What are the official names of this protein?
Sesquiterpene synthase MAJ_08936, Bacterial terpene synthase-like protein MAJ_08936, BTPSL.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: PPE38_MYCTO
Sequence: MILDFSWLPPEINSARIYAGAGSGPLFMAAAAWEGLAADLRASASSFDAVIAGLAAGPWSGPASVAMAGAAAPYVGWLSAAAGQAELSAGQATAAATAFEAALAATVHPAAVTANRVLLGALVATNILGQNTPAIAATEFDYVEMWAQDVGAMVGYHAGAAAVAETLTPFSVPPLDLAGLASQAGAQLTGMATSVSAALSPIAEGAVEGVPAVVAAAQSVAAGLPVDAALQVGQAAAYPASMLIGPMMQLAQMGTTANTAGLAGAEAAGLAAADVPTFAGDIASGTGLGGAGGLGAGMSAELGKARLVGAMSVPPTWEGSVPARMASSAMAGLGAMPAEVPAAGGPMGMMPMPMGMGGAGAGMPAGMMGRGGANPHVVQARPSVVPRVGIG
What are the official names of this protein?
Uncharacterized PPE family protein PPE38.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: MRAZ_CAUVC
Sequence: MFLSTFEKQLDSKRRIVVPQEFRAAVSGPFDGIFCFPSIEADCLEAGGKALFDRYQAVIEEMPFGDPTRTALETSILGGMAKLTFDTAGRITLPDHLCDMFGLTDSVAVVGMGERFQIWSREAFQAHRAQQRDLAREGLAALRAQQRAAKFAGGAA
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: COAX_DESDA
Sequence: MQPELLLFDIGNTSIKIGLAHERQVVTSYTLRTDAGQTADDLGLKLATLLGHAGVTPQSLRACVASSVVPGFDPLLREAVARYVDCPLYRVGADLSVPLENRYERPAEVGADRLVGAYAARRLYPEFPGLLVVDFGTAVTIDCVNGNAYMGGLIFPGPRTALSALSREAAKLPRVNLDVRADEPTPGRSTATSIQHGLVFGFACMVEGLAQRLKRQLPGPARVLGTGGFAASIARVSPVFDHVLPALLLEGLRRLYYEERTAF
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_DICNV
Sequence: MTQRHWLELTLIADNDDDVLLLETALECAGAVAVTYQAANEEEIFEPEIGTTPMWSKTGVTGLFPLDTDPNAVIELLMQALGEDYPIAQHLLPESDWTRAWLEHFQPIAFGNHFWVAASEHVIEEHDAKVLRLDPGLAFGTGTHPSTAMCLHYLVNHAALHGKTVYDYGCGSGILGIAAAMMGAKAVYQTDIDPQALTASYENAQKNQVAEKIFLCEQPDLAPAVDLLVANILLEPLCALRAQFEKHLHAQSVMIFSGLLERQQQKLEQAYQDHYRIERINCRAGWILLRLTSL
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IGD_HUMAN
Sequence: RLQLQESGPGLVKPSETLSLTCIVSGGPIRRTGYYWGWIRQPPGKGLEWIGGVYYTGSIYYNPSLRGRVTISVDTSRNQFSLNLRSMSAADTAMYYCARGNPPPYYDIGTGSDDGIDVWGQGTTVHVSSAPTKAPDVFPIISGCRHPKDNSPVVLACLITGYHPTSVTVTWYMGTQSQPQRTFPEIQRRDSYYMTSSQLSTPLQQWRQGEYKCVVQHTASKSKKEIFRWPESPKAQASSVPTAQPQAEGSLAKATTAPATTRNTGRGGEEKKKEKEKEEQEERETKTPECPSHTQPLGVYLLTPAVQDLWLRDKATFTCFVVGSDLKDAHLTWEVAGKVPTGGVEEGLLERHSNGSQSQHSRLTLPRSLWNAGTSVTCTLNHPSLPPQRLMALREPAAQAPVKLSLNLLASSDPPEAASWLLCEVSGFSPPNILLMWLEDQREVNTSGFAPARPPPQPGSTTFWAWSVLRVPAPPSPQPATYTCVVSHEDSRTLLNASRSLEVSYVTDHGPM
What is the function of this protein?
Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).  IgD is the major antigen receptor isotype on the surface of most peripheral B cells, where it is coexpressed with IgM.  The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases.  Soluble IgD (sIgD) concentration in serum is below those of IgG, IgA, and IgM but much higher than that of IgE.  IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites.  After the antigen binds to the B cell receptor, the secreted form sIgD is shut off.  IgD is a potent inducer of TNF, IL1B, and IL1RN.  IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells.  Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD (PubMed:8774350, PubMed:11282392, PubMed:10702483, PubMed:16895553).
What are the official names of this protein?
Immunoglobulin delta heavy chain, Immunoglobulin delta heavy chain WAH.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: 2SS3_CAPMA
Sequence: EPLCRRQFQQHQHLRACQRYLRRRAQRGGLADEQRGPALRLCCNQLRQVNKPCVCPVLRQAAHQQLYQGQIEGPRQVRRLFRAARNLPNICKIPAVGRCQFTRW
What is the function of this protein?
Heat stable 2S seed storage protein having sweetness-inducing activity.
What are the official names of this protein?
Sweet protein mabinlin-3, Mabinlin III, MAB III.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: ADAM7_HUMAN
Sequence: MLPGCIFLMILLIPQVKEKFILGVEGQQLVRPKKLPLIQKRDTGHTHDDDILKTYEEELLYEIKLNRKTLVLHLLRSREFLGSNYSETFYSMKGEAFTRHPQIMDHCFYQGSIVHEYDSAASISTCNGLRGFFRINDQRYLIEPVKYSDEGEHLVFKYNLRVPYGANYSCTELNFTRKTVPGDNESEEDSKIKGIHDEKYVELFIVADDTVYRRNGHPHNKLRNRIWGMVNFVNMIYKTLNIHVTLVGIEIWTHEDKIELYSNIETTLLRFSFWQEKILKTRKDFDHVVLLSGKWLYSHVQGISYPGGMCLPYYSTSIIKDLLPDTNIIANRMAHQLGHNLGMQHDEFPCTCPSGKCVMDSDGSIPALKFSKCSQNQYHQYLKDYKPTCMLNIPFPYNFHDFQFCGNKKLDEGEECDCGPAQECTNPCCDAHTCVLKPGFTCAEGECCESCQIKKAGSICRPAKDECDFPEMCTGHSPACPKDQFRVNGFPCKNSEGYCFMGKCPTREDQCSELFDDEAIESHDICYKMNTKGNKFGYCKNKENRFLPCEEKDVRCGKIYCTGGELSSLLGEDKTYHLKDPQKNATVKCKTIFLYHDSTDIGLVASGTKCGEGMVCNNGECLNMEKVYISTNCPSQCNENPVDGHGLQCHCEEGQAPVACEETLHVTNITILVVVLVLVIVGIGVLILLVRYRKCIKLKQVQSPPTETLGVENKGYFGDEQQIRTEPILPEIHFLNKPASKDSRGIADPNQSAK
What is the function of this protein?
May play an important role in male reproduction including sperm maturation and gonadotrope function.  This is a non catalytic metalloprotease-like protein (By similarity).
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 7, ADAM 7, Sperm maturation-related glycoprotein GP-83.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NUOD_MYCSS
Sequence: MTTPPGPPNAGGDARTGTDTVIVVGGEDWEQVVAAAEQAQAGERIVVNMGPQHPSTHGVLRLILEIEGETITEARCGIGYLHTGIEKNLEYRNWTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGVTDAIPERVNVIRVMLMELNRISSHLVALATGGMELGAMSAMFYGFREREEILSVFEMITGLRMNHAYIRPGGLAADLPDGAVPRIRELLALLPGRLRDLENLLNENYIWKARTQGIGYLDLAGCMALGITGPVLRSTGLPHDLRRAQPYCGYEDYEFDVITDDGCDAYGRYLIRVKEMRESLKIVEQCVDRLKPGPVMIADKKLAWPADLELGPDGLGNSPAHIARIMGQSMEGLIHHFKLVTEGIRVPAGQVYTAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMCEGGMVADAISAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NARL_ECOL6
Sequence: MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF
What is the function of this protein?
This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted by either the NarX or NarQ proteins.
What are the official names of this protein?
Nitrate/nitrite response regulator protein NarL.
Protein: L_SENDE
Sequence: MDGQESSQNPSDILYPECHLNSPIVRGKIAQLHVLLDVNQPYRLKDDSIINITKHKIRNGGLSPRQIKIRSLGKALQRTIKDLDRYTFEPYPTYSQELLRLDIPEICDKIRSVFAVSDRLTRELSSGFQDLWLNIFKQLGNIEGREGYDPLQDISTIPEITDKYSRNRWYRPFLTWFSIKYDMRWMQKTRPGGPIDTSNSHNLLECKSYTLVTYGDLVMILNKLTLTGYILTPELVLMYCDVVEGRWNMSAAGHLDKRSIGITSKGEELWELVDSLFSSLGEEIYNVIALLEPLSLALIQLNDPVIPLRGAFMRHVLTELQTVLTSRDVYTDAEADTIVESLLAIFHGTSIDEKAEIFSFFRTFGHPSLEAVTAADKVRAHMYAQKAIKLKTLYECHAVFCTIIINGYRERHGGQWPPCDFPDHVCLELRNAQGSNTAISYECAVDNYTSFIGFKFRKFIEPQLDEDLTIYMKDKALSPRKEAWDSVYPDSNLYYKAPESEETRRLIEVFINDENFNPEEIINYVESGDWLKDEKFNISYSLKEKEIKQEGRLFAKMTYKMRAVQVLAETLLAKGIGELFSENGMVKGEIDLLKRLTTLSVSGVPRTDSVYNNSKSSEKRNEGMKKKNSGGYWDEKKRSRHEFKATDSSTDGYETLSCFLTTDLKKYCLNWRFESTALFGQRCNEIFGFKTFFNWMHPILERCTIYVGDPYCPVADRMHRQLQDHADSGIFIHNPRGGIEGYCQKLWTLISISAIHLAAVRVGVRVSAMVQGDNQAIAVTSRVPVAQTYKQKKNHVYEETTKYFGALRHVMFDVGHELKLNETIISSKMFVYSKRIYYDGKILPQCLKALTRCVFWSETLVDENRSACSNISTSIAKAIENGYSPILGYCIALYKTCQQVCISLGMTINPTISPTVRDQYFKGKNWLRCAVLIPANVGGFNYMSTSRCFVRNIGDPAVAALADLKRFIRADLLDKQVLYRVMNQEPGDSSFLDWAPDPYSCNLPHSQSITTIIKNITARSVLQESPNPLLSGLFTETSGEEDLNLASFLMDRKVILPRVAHEILGNSLTGVREAIAGMLDTTKSLVRASVRKGGLSYGILRRLVNYDLLQYETLTRTLRKPVKDNIEYEYMCSVELAVGLRQKMWIHLTYGRPIHGLETPDPLELLRGTFIEGSEVCKLCRSEGADPIYTWFYLPDNIDLDTLTNGSPAIRIPYFGSATDERSEAQLGYVRNLSKPAKAAIRIAMVYTWAYGTDEISWMEAALIAQTRANLSLENLKLLTPVSTPTNLSHRLKDTATQMKFSSATLVRASRFITISNDNMALKEAGESKDTNLVYQQIMLTGLSLFEFNMRYKKGSLGKPLILHLHLNNGCCIMESPQEANIPPRSTLDLEITQENNKLIYDPDPLKDVDLELFSKVRDVVHTVDMTYWSDDEVIRATSICTAMTIADTMSQLDRDNLKEMIALVNDDDVNSLITEFMVIDVPLFCSTFGGILVNQFAYSLYGLNIRGREEIWGHVVRILKDTSHAVLKVLSNALSHPKIFKRFWNAGVVEPVYGPNLSNQDKILLALSVCEYSVDLFMHDWQGGVPLEIFICDNDPDVADMRRSSFLARHLAYLCSLAEISRDGPRLESMNSLERLESLKSYLELTFLDDPVLRYSQLTGLVIKVFPSTLTYIRKSSIKVLRTRGIGVPEVLEDWDPEADNALLDGIAAEIQQNIPLGHQTRAPFWGLRVSKSQVLRLRGYKEITRGEIGRSGVGLTLPFDGRYLSHQLRLFGINSTSCLKALELTYLLSPLVDKDKDRLYLGEGAGAMLSCYDATLGPCINYYNSGVYSCDVNGQRELNIYPAEVALVGKKLNNVTSLGQRVKVLFNGNPGSTWIGNDECEALIWNELQNSSIGLVHCDMEGGDHKDDQVVLHEHYSVIRIAYLVGDRDVVLISKIAPRLGTDWTRQLSLYLRYWDEVNLIVLKTSNPASTEMYLLSRHPKSDIIEDSKTVLASLLPLSKEDSIKIEKWILIEKAKAHEWVTRELREGSSSSGMLRPYHQALQTFGFEPNLYKLSRDFLSTMNIADTHNCMIAFNRVLKDTIFEWARITESDKRLKLTGKYDLYPVRDSGKLKTISRRLVLSWISLSMSTRLVTGSFPDQKFEARLQLGIVSLSSREIRNLRVITKTLLDRFEDIIHSITYRFLTKEIKILMKILGAVKMFGARQNEYTTVIDDGSLGDIEPYDSS
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: UNG_VACCA
Sequence: MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
What is the function of this protein?
Plays an essential role in viral replication as a component of the DNA polymerase processivity factor.  Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Protein: CSPL9_SORBI
Sequence: MAAGQPRPPPPPSSVRTERVLRAACAAMAAAGALLLGFSAETKTVIFVQKKAVPKDVQALWVLIVAAAAAAAYHAAQLARCLCMDRLAGGGGGCRRLRRAVACATFLLDKGCAYMVLATTVAALQACFVGLLGVEALQWSKLCNIYTRFCEQAAAGMVCSLVAAAGMAVLSAFSARDLFRRRRPCSPCVQVQQV
What are the official names of this protein?
CASP-like protein 2C2, SbCASPL2C2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_SALTI
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPNNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTGENWFALPKERLWVTVYETDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIEAVAKVTGSTDLGNKSLRVIADHIRSCAFLVADGVLPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIEVMGSAGEELKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLQGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVEAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGAGFTFAVDDTQKYGQAIGHLGKLSAGALKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVAQKGSLVSDKVLRFDFSHNEAMKPSEIREVEDLVNAQIRRNLPIETNIMDLDAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGIRRIEAVTGEGAMATVHAQSDRLNDIAHLLKGDSQNLGDKVRAVLERTRQLEKELQQLKDQAAAQESANLSSKAVDLNGVKLLVSELAGIEPKMLRTMVDDLKNQLGSTVIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVQGWVSAKLQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM14_SCHPO
Sequence: MPTVQTPSQRRANTQFQKNITRRVKTNSKERYVAKHPPTKIPRNIAMFFILLMSGGIILGILRFLLTFFS
What is the function of this protein?
May interact with target proteins during translocation into the lumen of the endoplasmic reticulum.  May protect unfolded target proteins against degradation and facilitate correct glycosylation (By similarity).
What are the official names of this protein?
Protein tam14, Transcripts altered in meiosis protein 14.
What is the protein family that this protein belongs to?
Belongs to the RAMP4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: DXR_DESOH
Sequence: MKRLTLLGSTGSIGVNTLKVVSRFCDRFSVEALCARGSVDTLAEQVQRFSPSLAVVIDAPTAQALKERLPAGSRTEVLFGEAGYCHAVSLPGVDMVVSAMVGAAGLGPTIAAIKAGKAVALANKEVLVMAGETVMALAAQKGVPLLPIDSEHSAIFQCLQGNDKTFLSKIHLTASGGPFLNKTRQEIETATPEQALAHPTWTMGKKISIDSATLMNKGLEVIEARFLFDVPADCIEVVVHPQSIIHSMVSYIDGSMMAQLSVPDMKGAIAYALSYPERLDLNQPAPDLAALEQLTFFSPDLDRFPCLGLAFEACRRKKTFPAVLNAANEVAVDAFLREAIPFGRIPRVIEQVLAEHTGVTDPSLSDIKDADAWARQRAGALLP
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: T7390_ILLWI
Sequence: LKFVVLICLVIMASTSAQQCGDETCGAGTCCAVFSQNHCRRLSQMYDLCSDHADASPSGNYLFFCPCEPGLHCDRNTWTCTEGSSRSE
What are the official names of this protein?
U1-hexatoxin-Iw1b, U1-HXTX-Iw1b, Atracotoxin-Hs20f7390, AcTx-Hs20f7390.
What is the protein family that this protein belongs to?
Belongs to the MIT-like AcTx family.
What are the subcellular locations of this protein?
Secreted.
Protein: ALE1_SCHPO
Sequence: MAYLIDIPFEYFSSFLGVHPDQLKLLFCFLSAYPFAGILKRLPSAPWIRNLFSISIGLFYLIGVHHLYDGVLVLLFDALFTYFVAAFYRSSRMPWIIFIVILGHTFSSHVIRYIYPSENTDITASQMVLCMKLTAFAWSVYDGRLPSSELSSYQKDRALRKIPNILYFLGYVFFFPSLLVGPAFDYVDYERFITLSMFKPLADPYEKQITPHSLEPALGRCWRGLLWLILFITGSSIYPLKFLLTPKFASSPILLKYGYVCITAFVARMKYYGAWELSDGACILSGIGYNGLDSSKHPRWDRVKNIDPIKFEFADNIKCALEAWNMNTNKWLRNYVYLRVAKKGKRPGFKSTLSTFTVSAMWHGVSAGYYLTFVSAAFIQTVAKYTRRHVRPFFLKPDMETPGPFKRVYDVIGMVATNLSLSYLIISFLLLNLKESIHVWKELYFIVHIYILIALAVFNSPIRSKLDNKIRSRVNSYKLKSYEQSMKSTSDTDMLNMSVPKREDFENDE
What is the function of this protein?
Membrane-bound O-acyltransferase that mediates the incorporation of unsaturated acyl chains into the sn-2 position of phospholipids.
What are the official names of this protein?
Lysophospholipid acyltransferase, LPLAT, 1-acyl-sn-glycerol-3-phosphate acyltransferase, AGPAT, Lysophosphatidic acid acyltransferase, LPAAT, Lysophosphatidylcholine acyltransferase, LPCAT, Lysophosphatidylethanolamine acyltransferase, LPEAT.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Protein: PLPR3_HUMAN
Sequence: MISTKEKNKIPKDSMTLLPCFYFVELPIVASSIVSLYFLELTDLFKPAKVGFQCYDRTLSMPYVETNEELIPLLMLLSLAFAAPAASIMVAEGMLYCLQSRLWGRAGGPAGAEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCEVNPYITQDICSGHDIHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISDTTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKPAAPAPAKDALRALTQRGHDSVYQQNKSVSTDELGPPGRLEGAPRPVAREKTSLGSLKRASVDVDLLAPRSPMAKENMVTFSHTLPRASAPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEGRGLGLPDDASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEEDEGPAPPSLYPTVQARPGLGPRVILPPRAGPPPLVHIPEEGAQTGAGLSPKSGAGVRAKWLMMAEKSGAAVANPPRLLQVIAMSKAPGAPGPKAAETASSSSASSDSSQYRSPSDRDSASIVTIDAHAPHHPVVHLSAGGAPWEWKAAGGGAKAEADGGYELGDLARGFRGGAKPPGVSPGSSVSDVDQEEPRFGAVATVNLATGEGLPPLGAADGALGPGSRESTLRRHAGGLGLAEREAEAEAEGYFRKMQARRFPD
What are the official names of this protein?
Phospholipid phosphatase-related protein type 3, Inactive phospholipid phosphatase PLPPR3, Lipid phosphate phosphatase-related protein type 3, PAP-2-like protein 2, Plasticity-related gene 2 protein, PRG-2.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MARC2_PIG
Sequence: LWIYPVKSCKTEAYRCILTTVDPDTGVIDRKVGDPVYRMV
What is the function of this protein?
Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles.  As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability.  May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis.  Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction.
What are the official names of this protein?
Mitochondrial amidoxime reducing component 2, mARC2, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2, MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2.
What are the subcellular locations of this protein?
Peroxisome. Mitochondrion outer membrane; Peripheral membrane protein.
Protein: CVC2_EHV1V
Sequence: MAEYVNYVLGSLYVSDTATSTIPTDVRNFIAPPFPLNFWSGPTFTVRSNTRADPLKLVAARHRAAAAAIDTLEAQSQYGVANVDALIRPLERQVAKVADALAALEDAARAAESADAATPQVNASEADQRPDNIGQSLSEIQIAKNDVPMEFDTNLAVDLLATVFVSRAAGGSNGVVFGTWYRALQDRLVTERPVATRSIDYRDGRMSKTFMTTAVVSLQSCGRLYIGNRPYSAFEAAVLCLHLAHRAVNSNYTYPTSFSGLIEQLPVYIEAFSTALGDGTLGKVGYEFNGARLPKNQFHVPGGGGRYERGALNGHGVLETLIRLKVLPAIPGSLGTTSTAVGPELDADQTAYIDDVNKAAAAFLVRAQNLFLTEDQTLLRSTINTITALLLLRRLLWNGNVYTDRLRNNFQLGAIVPNLAVSQRDARGASGGDAAAMVSRSGNNNFTFLCERYVSPIYIANREVELTQLFPGLAALCLDAQTVARDQPQHRAVNVSTGRNQTNLTRLIGIELENRRRTAPVPINEVLAAHDAVALQYERGLGLLMQKPRLRASLEETRRLGQFNVASDYDLLYFVCLGYIPSLTSAM
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.  Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
What are the official names of this protein?
Capsid vertex component 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SEC65_CANGA
Sequence: MPKLEEIEDYDDIDNMDMDLAELDPTLNTPIAPKITPTVVRSQDIEEEERKKQYAGSNKEMISFINPQTGKVEESAPITKQELDEVKKFQVLYPCYFDKNRSHKEGRRVPIEMAVENPLAKTISDAVREYGLLSIFEGDKCHPQDFGNPGRIRVLLKEEGKLVPSASKFSGGKRQLMKLVAEYLQKHPTTVESLRELPYGPDFDNIEFKKIPKVKGFKMNDIVPLHSPYLWGHPMTKSIYEAPKIEAPEKQFKAPKNKFKVVRR
What is the function of this protein?
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane.  It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).
What are the official names of this protein?
Signal recognition particle SEC65 subunit.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDCB_KLEPN
Sequence: MKNLSPLHAESRVSWLAHTASACLIDEARLSPKPGLVDSRGNGAHQDLNLALMERSARSLQPTFHALAEQSWRRPADIALRETVGRLGREGEAQMMLATGGVNTHRGAIWALGLLVSAVAMLGGEGQSQAIADAAAALARLPDGFAPKSFSKGLRASRRWQVPGAREEAQCGFPHITRLALPQLQHSRARGASEPQAQLDALMAIMTSLSDTCVLSRAGMAGLQAMQQGACEVLAAGGCASFAGRAALARLDAIMLALNASPGGAADLLAATLFLDRVAG
What is the function of this protein?
Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.
What are the official names of this protein?
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.