PharMolix/UniProtQA huggingface dataset:
Protein: LOLB_XANOP
Sequence: MSKALRTLALSGLVLVGLSACVSVPRGQGSGAAVVEQISDSARQGEAARQAWLQQHPNWSFQGRVAISKDRNGGSGRIDWQQDGPRYRVQLSAPVTRQSWVLTGDTTTGAGRLEGLDGGPRSGSDAEKVLLEATGWTIPVNQMPDWVRALRIADAGAARVELDAAGRPRTVQQDGWTIDFLAWTPASADQPELPQRIEARYGEAKVRLLVDQWTVSP
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y0019_DICDI
Sequence: MSNNKIIESLAILYLNNYINDNDIYSLSLINREFHINIIKDDYFYSTINKNYLFLYIKIFKLLSIKVKLNPNWINIINNNNNINNNNNNNNNNNNNNNNNNNNKIKLIKNNFSVISERLNFLIQCKFNLHRYLDNNDLFITILRGEKLSTLDRIICFSIIYSQDQILLFLLNFILSNINCNNNNNNNNNNNNNNNNNNISNISNSNRLLANNSYNIQFNQQIPTQNELINLNKCLQFSTSTTTTTTTTMVPPFNENILKVYPIYFAIVKVIGGGSLVRFLLSILPNVYNITNVNCKLPITNRSALFYSTTREMTLLLLQLGCNIHDMDYKGMLPIHYHSLNGHVDVVKCLIDDSTINALDQSNNTPLNLASLSGNLSLAKILLNSGARLSIDNLNGRYPIHNACVNGNIDLIRYFLELYSKMNSTTLLPSTTTTTTTTTTTMTTTTTTAITTTTATTIQNNSNNLTNSNSSSVGGLRISNGGNTQQQSIQIPDKENNTPIDLLVLNNHFTIAIELLKYEGYIVGKEEFNFKTARKIGAGAFGDVYLVEWRNKNVAVKRVKIEKILESGKSYQWIRDKFILEAVLMVKLSNFSSFVKLYATCIEEKELLLVLEFCDNGSLYTILNTIPIGGAGANNNNNNNNNNDIIQSLPSINTLSLNIANGMNYLHSLKPQIIHRDLTSQNILIDRNGIAKIADFGISRFKNDIGDKTMTSIGNPRFRSPEVTKGQKYSEKVDVFGFGMILYEMFTRRVPFHDYEQIAASFKIANAERPPLPQTIDHRWSNLIQICWDQNPNNRPSFDQILTIIQNLPIANIPKFLVPLQQNQNQIQNQNQNQNQNNGKLDLSTSSSSITNLNNAVTAKLSLSTSGGLFSGDSDYTVGTCSGYDIGYDNDGDIIDYSSDQNDSDLYD
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0278521.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TOPZ1_BOVIN
Sequence: MPRAPPSGPTTAPGREDDARGLRKRSRRPGLGEAGGCGPEAEGLEESRQKRRMVARASGREEVESDKSAKEKRKVTEASSDDPQPGIDLVRKESLTSSESFPTVECSEFQSMAFLQSLGKERLVEGIKRRIRIKKCKSLESPALKMTENKATQNSKVEFQDELYKNTLKYSCNSLSPGVENNSVLKLHDCSCLSHSKDCNDENNLAYKPDGGCMHVPENSSKSKKENPRSLIDKTDPSNIPQLLQTEENVMRVSQLLLEENDSYLSKNNGLFSCLQSEKTKHSIEESSIGRKSRKRMKVSEKGNGMVIEMKFSNMCNKSELMLQGNQTGADGKETEILEAKKSSLKVLRKVNNNTLSPMDPLLSLPETGKKTSPEHCANAVFQKALEQLSKEETKNVSQPLGCTSMDPPEDYFKSMKNSLVKSLSDCFPIEKRSSRESLKNEAEESKYSCQRTIPMTGKRTWPCYSCARISAQCWKKASLPQSSRQDDFLKHQMNQTHLTDSKLMLQSSVTETNSASSSIEKLDSNLNCLPSVSTVEPTSVVIKEPIVNDDEKMKSEELSRSASEVVSNTTEDTSLTNMTHNLTGSKKKDRGNLTKLNLTVASQDGQEANNSTSKTVHRKACITKQALVVPDLVKILNTGRLTNFKIPLLKNKTEKRKEINAKSSEREVYSPLELLDSVSGAEVRQSRTKENAVTVTSGPQSLSIQRSVIPVQASSDSFCSKNSCIIAPSFLKQGNNKQPSNHISASGRIISNNAAGSLTVENNTFSCDPGCIEKNPTFYSNEQEPFKAVSSEVSGRKMTENFSEIKVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFPSEVPMISQEPNVAEEHQSTDSKHMELPDKKEPSNALRELPVPDPGSMKSEICASLSAASEIKHDSKDANISLGEVTHETSSNEKPRGLSEQTKSSDLDEKCRFSDKVAIREEKETISEVCRRDSKNTEIMVGECHLAALVSKPLCLPVPLPPLNLNAHQEDTLLNPQMNDFRLPGKHSVLKLQNPEICEIFKREKNVGVFQKPLGLMIPHRYCKFHFNTLRGCERSQCKFGHVPEQGDEKVCMDVFKKYISINELCLLQRAANMFMEYYRKFLPGIHFDLQVLNDLLSSLLKHCLLKEVFQVMNLCIMIKMLPALKILLKIFEYVATMKLRNAVPALINIFCKLLEAGMVLDPEHFNYIVKLLYQVQASKQEITAVLEMKSRLHMRQFKKNWKCDLEAALNEIEHCKEKGDWTKLGNVYLNIKMSCEKFADFQRFCACIAETLTKDCKEERPGVPFCEFAETVSKDLQNSEVDKTLLGRIGISAMYFYHKLLQWSKGRKVLDKLYELKIHFTSLKGLIGPEKLAPRCQIVNIAAEIFLKSGSLDGAIWVLRESEWIINTPVWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSLLFNKLLDACIESNSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFLVSNASSIQSPGTSTQMLQIVLKRSEENKSRSKDDYQAAVERLITAARISDPKLFIKHMTVNVNKEQVYSLEQCSALKWLKENMKWAGKVWLFNNH
What is the function of this protein?
Important for normal spermatogenesis and male fertility.  Specifically required for progression to the post-meiotic stages of spermatocyte development.  Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
What are the official names of this protein?
Protein TOPAZ1, Testis- and ovary-specific PAZ domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL23_HAEIE
Sequence: MSQERLLSVLRAPHISEKATNNAEKSNTVVLKVALDANKAEIAAAVAQLFEVKVDSVRTVVVKGKTKRRGNKMGRRSDWKKAYVTLAKAKIWTSWTVQSNRRKLENGYR
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ALF1_PORGI
Sequence: MNKEQLQQMRQAPGFVGALDQSGGSTPKALKAYGIQPDAYQSEEEMFDLIHQMRTRMITSPAFATGKIIGVILFERTMRGKIEGMPTADFLWEKRHIVPFLKVDKGLQDEANGVQLMKPFPELGKLCEEAVGYHVFGTKMRSVIKQANEQGIRDIVEQQFQWGKEILSHGLVPILEPEVDIHCPEKAKAEEILKRELLAQLDKMTEPVMLKITIPTVDNFYKEIIEHPMMLRVVALSGGYSREQANELLSRNHGVIASFSRALVEGLSARQTDAEFNAMLEASIEDVYQASIK
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: SNX4_SCHPO
Sequence: MSDSVNLDEPSTNSTHFLQCLVTEPRKELQGSRDTHVSYLIITKTNLSIFTRAECKVRRRFSDFVKLQEILSRMNEDCVVPPLPAKHKLEYIKGGRFSDNFINRRAKLLNRYITRCALHPVLHQSPHFIAFLENPNWNNYVRFFIQPKLNNTSKLDEISDSLLNAFSKLKEEPTEFDIQRDHVQQFMFGISNLEGSIQKLLRLEKALESDYEDVSIQFDRLASLDQALDVPIESIQNALQQTGTEYANLTEKLTLLLDTIKDVESYAHSLKELLKRRDQKQQDVEALQEYSAKLSLERDKISSGGSNGFSLSKTLDDLRGIDHNDTRLKRLEHVQSELQAVEQAIQEASAVHDAFNQRVREESKLFDSVRQSEMLSAISDYANVHVEFFTNIRDLWIRVKQ
What is the function of this protein?
Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells.  Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), autophagy, mitophagy, and pexophagy.
What are the official names of this protein?
Sorting nexin-4, Autophagy-related protein 24.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures. Associates to phosphatidylinositol 3-phosphate, necessary for peripheral membrane localization to the perivacuolar punctate structures.
Protein: CUTC_PASMU
Sequence: MKIEVCIDNIESVHIAQNAGADRLELCACLSVGGVTPSYSLIKSAVDFANIPCYVMIRPRAGDFLFSTQEVNMMLDDIHLAKQLGAQGIVIGALTKHADIDLSVCETLIQAAEGLGVTFHRAFDLCRDPVTSLEQLIQLGCERVLTSGQKASAVEGQPLIKQLVSQASNRIRIMAGAGINAQNAALLVKNTGITELHLSGKGYRLSEMPYHANAVMGENSEDDQKIWRTDFATIRAVKTSVEKY
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXD3_HUMAN
Sequence: MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGERDNRCNRAHEEAQKLLPPPPPPPPPPALPSRRPGPEPCAPPAYAHPAPASLRECGSGRGKASPATGRRDLAI
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction delta-3 protein, Connexin-31.9, Cx31.9, Gap junction alpha-11 protein, Gap junction chi-1 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Delta-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: ISPD_HAHCH
Sequence: MFVDSMEEHKLWVIVPAAGVGSRMGGERPKQYLKLIDRSVLEHTLDRLLSAPGISQIYLPLHPQDKWWPEIADKYTGKVISVAGGEERSTSVLNALEKIESHAAIEDWVLVHDVARPCFRISDISNLMRLLWNTQPGGLLGVPVADTVKRTNEKGEVLATVSRANLWRAYTPQMFRFGALLSALRQGSEKGVHITDEASAIEAQGLKPVMVEGHSDNIKITHPQDLPLAEIFLRRIMQEEE
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PANB_PHOLL
Sequence: MKPMTMTDLNQLKKEKRKFATITAYDASFAHLFAEQGIDVMLVGDSLGMTVQGADTTIPVTVEDIVYHTRCVRAGTPYTFIIADMPFMSYATPEQSCENAAKLMRAGANMVKLEGGSWLYDTINMLTERSVPVCAHLGLTPQSVHILGGYKVQGRDEVSANQLIKDAITLEKAGIQLLVLECVPVDLAKRITDELQIPVIGIGAGNVTDGQVLVMHDTLGITVSPPKFVKNFLEEAGNIRDAIRLYKEQVESGIYPGKEHSFY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPS_SACS2
Sequence: MAKDLTRGLLFKPIYKLYELVLWNQIRNGPLPDHVGIIPDGNRRWARDNNLSLNDAYFYGYKKLKEVLIWLLELGIKNITVFVLSTENCDKRKQNELSIITTYIKRGIQDLLEDPIVDKYEVKVSAIGKLDKLPKDLIDYLNRVVEKTSNYDKRKLTLAICYGGRQEILDAVVRLLDDYRNGKIVKSEINEETFRKYFYDSELQDIDLVIRTSGEVRISNFLLWHVAYSELFFCEAYWPEFRKIDLWRAIRSFQKRKRNFGA
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP).  It is probably the precursor of glycosyl carrier lipids.
What are the official names of this protein?
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific), Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: TPX_VIBC3
Sequence: MTVTFQNNPVSISGSFPKVGDRLPSFTLCGADLNDLNNEDFKGKKIVMSIFPSIDTPVCSKSVKVLQNALMTRSDTVLLCVSADLPFAMSRFCTEHAVANVTNASFFREPAFTERFGVNLNEGALRGLAARAVIVADEFGVITHSELVNEITNEPDYDRILMSL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: HSCA_PASMU
Sequence: MALLQIAEPGQSASPHQHKLAVGIDLGTTNSLIATVRSGQVDILLDEKERPLLPSVVHFEQDNVIVGYEAAELASQSPQNTIVSVKRLIGRSLADVQQRYPSLPYQFEASENGLPLIRTSKGTLSPVEISAEILKKLTALAEKRLAGELSGAVITVPAYFDDAQRQSTKDAAKLAGINVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSKGVFEVLATGGDTALGGDDFDHQLMDWIVAQSGIAPQNAQQQRQLTELATQIKIALTDKLETSISYQGWQGNISREQFNQLIQGLVKRSLLACRRALKDADVSADEVCEVVMVGGSTRVPFVREQVAAFFQKEPLTSIDPDKVVALGAGIQADILVGNKPDADMLLLDVIPLSLGIETMGGLVEKIIPRNTTIPVARAQEFTTFKDGQTAMSVHVVQGEREMVADCRSLARFSLRGIPAMAAGAAHVRVTYQVDADGLLSVTAMEKSTGVQSSIQVKPSYGLSDDEITNMLKASMLNAKEDIQARLLAEQRVEAQRVLESVGSALSADQDLLNDEELSAVKNAIISLQRLQKEGDTQEIKQGIKQLDLATQEFASRRMDKSIRQALAGKAIDDVMKNAK
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL35_COREF
Sequence: MKNKTHKGTAKRVKVTGSGKLVREQANRRHLLEGKPSTRTRRLKGIVEVSPADTKRMKRLLGKA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MURA_SALCH
Sequence: MDKFRVQGPTTLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDASQVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHITGLEQLGATIKLEEGYVKASVEGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLVTLGAKIAGQGTDRITIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKILCRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGARAEIESNTVICHGVETLSGAQVMATDLRASASLVLAGCIAEGTTIVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LNPB_TAKRU
Sequence: MGAIISRWKTKLTTVEQLENIDKEIKQLEEFRAKNQRLQKLWVGRLLLYSSALYLLISLFVYLLYLPEQWLLRLAMALPFFIYPVLVWFIRRFLIFLFSKRSERNNDKLEDLKATKKKILEEVMETETYKNAKAILERFDPDAKKKPELEATPVRPQMTPGAGQELRQRGVALRHMPMGTPVAVTPGARPPLGPGGTPVERVPLSAPGGPPERSGLAASVQMTPRSLGSPVPGVGMHPPGPPLARPVLPKDRGAVDRVIEYLVGDGPQNRYALICQQCFSHNGMALKEEFEYLAFRCAYCYFLNPARKMRPQAPRLPEFNFEKRLRAESSTPGPAPHSATDTEESAPPSRGMDKHGRA
What is the function of this protein?
Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology.  Involved in the stabilization of nascent three-way ER tubular junctions within the ER network.  May also play a role as a curvature-stabilizing protein within three-way ER tubular junction network (By similarity).
What are the official names of this protein?
Endoplasmic reticulum junction formation protein lunapark-B, ER junction formation factor lunapark.
What is the protein family that this protein belongs to?
Belongs to the lunapark family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Localizes at endoplasmic reticulum (ER) three-way tubular junctions, which represent crossing-points at which the tubules build a polygonal network.
Protein: CSRP3_RAT
Sequence: MPNWGGGAKCGACDKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKVCYGRKYGPKGIGFGQGAGCLSTDTGEHLGLQFQQSPKPARAATTSNPSKFSAKFGESEKCPRCGKSVYAAEKVMGGGKPWHKTCFPCAICGKSLESTNVTDKDGELYCKVCYAKNFGPTGIGFGGLTHQVEKKE
What is the function of this protein?
Positive regulator of myogenesis.  Acts as cofactor for myogenic bHLH transcription factors such as MYOD1, and probably MYOG and MYF6.  Enhances the DNA-binding activity of the MYOD1:TCF3 isoform E47 complex and may promote formation of a functional MYOD1:TCF3 isoform E47:MEF2A complex involved in myogenesis (PubMed:7954791, PubMed:9234731).  Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes.  Could play a role in mechanical stretch sensing.  May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures.  It is essential for calcineurin anchorage to the Z line.  Required for stress-induced calcineurin-NFAT activation.  The role in regulation of cytoskeleton dynamics by association with CFL2 is reported conflictingly.  Proposed to contribute to the maintenance of muscle cell integrity through an actin-based mechanism.  Can directly bind to actin filaments, cross-link actin filaments into bundles without polarity selectivity and protect them from dilution- and cofilin-mediated depolymerization; the function seems to involve its self-association.  In vitro can inhibit PKC/PRKCA activity.  Proposed to be involved in cardiac stress signaling by down-regulating excessive PKC/PRKCA signaling (By similarity).
What are the official names of this protein?
Cysteine and glycine-rich protein 3, Cysteine-rich protein 3, CRP3, LIM domain protein, cardiac, Muscle LIM protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere. Note=Nucleocytoplasmic shuttling protein (PubMed:19376126). Mainly cytoplasmic. In the Z line, found associated with GLRX3 (By similarity).
Protein: RL23_PECAS
Sequence: MIREERLLKVLRAPHVSEKASAAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKTKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL33_NITWN
Sequence: MAKAVTIKVKLVSSADTGFYYVAKKNSRTMTDKMVKKKYDPVARKHVEFREAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: LRC40_XENTR
Sequence: MSRFRRGGKAPDPLSGFRAPKEQEPAVPHGLIKAARKSGQLNLSARGLTDVPVSVWRINVDTPPEAHQNVDFGGSDRWWEQTDLTKLILASNKLQLLSEDISLLPALVVLDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPEEISLLNGLERLDLSNNDLGSLPCTLGSLPNLKSLQLEGNPLRGIRRDILNKGTQELLKYLKGRVQVPDVKTQEDENSTATAMTLPSESVVNTHAIVTLKTLEYCEKQASLIPEAVFNATGSSFITTVNFSKNQLTEVPARIVEMKDSVCDVNLGFNKISSISLNLCMLLKLTHIDMRNNVLTSLPSEMEAMTRLQSVILSFNRFKHFPDVLYRIPTLETILISSNQIGSIDPTQLIKMTKLSTLDLQNNDLLQIPPALGNCESLRALHLEGNPFRNPRAAILAKGTVAVLEYLRSRIPT
What are the official names of this protein?
Leucine-rich repeat-containing protein 40.
Protein: PORTL_BPE15
Sequence: MAETEKERLLKQLAQLKNERTSFESHWLDLSDFINPRGSRFLTSDVNRDDRRNTKIVDPTGSMAQRILSSGMMSGITSPARPWFKLATPDPDMMDYGPVKIWLEVVQRRMNEVFNKSNLYQSLPVMYASLGTFGTGAMAVMEDDQDVIRTMPFPIGSYYLANSPRGSVDTCIRQFSMTVRQMVQEFGLDNVSTSVKGMWENGTYETWVEVNHCITPNVNRDSGKMDSKNKPYRSVYFESGGDSDKLLRESGFDEFPILAPRWEVNGEDVYASSCPGMLALGQVKALQVEQKRKAQLIDKATNPPMVAPTSLKNQRVSLLPGDVTYLDVISGQDGFKPAYLVNPNTADLLADIQDTRQTINSAYFVDLFMMLQNINTRSMPVEAVIEMKEEKLLMLGPVLERLNDEALNPLIDRVFSIMARKNMLPEPPDVLQGMPLRIEYISVMAQAQKSIGLTSLSQTVGFIGQLAQFKPEALDKLDVDQAIDAFSEMSGVSPTVIVPQEQVQGIREERAKQAQAAQAMAMGQAAAQGAKTLSETQTSDPSALTAIANAAGAPQQ
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.
What are the official names of this protein?
Portal protein, Head-to-tail connector.
What is the protein family that this protein belongs to?
Belongs to the podoviridae head-to-tail connector protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ATPB2_SYNC1
Sequence: MKRQADRSGTVVAVRGGIVDARFDGEMPALHSLLLAGAQDEIVVEVMLHLDGGHVRGNALTPTQGLACGDTIKDSGAPLQAPVGQAILGRVFNVFGQPIDRREPPDGCRWRSVLTKPAGLTERSSKTEMFITGIKAIDVLAPLERGGKAGLFGGAGVGKTVLITELIHNMVGQHEGVSLFCGIGERCREGEELFREMREAGVLDNTVMVFGQMNEPPGARFRVGLTALTMAEYFRDDQGRDVLLLIDNIFRFIQAGMEISGLLGLMPSRLGYQPTMGTELAELQERISSTRHAAITSIQAVYVPADDFTDPAAVHTFSHLSASIVLSRRRASEGLYPAIDPLASTSNILNPRIVGERHYRLAQEIRRTLATYEELKDIIAMLGLEELSREDRRIVFRARRLERFLTQPFHTTQQFTGMQGRTVALDAALNGCEAILNDEFSEAPEKILYMIGGLEEARQRLREEETAGHGEEPP
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEUC_MYCGI
Sequence: MAVANQPRTLAEKVWSDHVVVSGSGEGAAREPDLIYIDLHLVHEVTSPQAFDGLRLAGRPVRRPDLTIATEDHNVPTVDIDKPIADPVSRTQVETLRRNCEEFGIRLHPMGDVEQGIVHIIGPQLGLTQPGTTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGELPPGVSAKDVILAVIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMIAPDETTFEFLKGRPHAPQGADWDAAVEAWKLLRTDEGAQFDTEVYIDAASLSPFVTWGTNPGQGVPLSDSVPDPEMIFDEGERSAVEKALAYMDLRPGTPMREIPVDAVFVGSCTNGRIEDLRVVADVLRGRTVADDVRMLVVPGSMRVRAQAEAEGLGEIFTAAGAEWRQAGCSMCLGMNPDQLAPGERCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLTAEPTR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: LEPA_BACC3
Sequence: MNKEERAKRQSKIRNFSIIAHIDHGKSTLADRILEKTNALTQREMKAQLLDSMDLERERGITIKLNAVQLNYKAKDGEEYILHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNNLEILPVINKIDLPSADPERVRQEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDSEEPLQCMIFDSLYDPYRGVIAYIRVVNGTVKVGDKVRMMATGKEFEVTEVGVFTPKTTQRDELTVGDVGFLAASIKNVGDTRVGDTITHAKRPAAEPLAGYRKLNPMVFCGLYPIDSARYNDLRDALEKLELNDSALEFEPETSQALGFGFRCGFLGLLHMEIIQERIEREFKIDLITTAPSVIYKVFLTNGEDMIVDNPSNMPDPQIIDRVEEPFVKAAIMVPNDYVGAVMEICQGKRGTFIDMQYLDETRVTLTYEIPLSEIVYDFFDQLKSNTKGYASFDYELIGYKPSKLVKMDILLNSEQVDALSFIVHRDSAYDRGKVIVEKLKELIPRQQFEVPIQATIGNKVVARSTIKAMRKNVLAKCYGGDISRKRKLLDKQKEGKKRMKSVGSVEVPQEAFMAVLKMDDN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2275_LACPL
Sequence: MSSLDKTMYFDFDNDSVKDVHDTLTTVYEALQEKGYNPINQIVGYLLSGDPAYIPRLKDARNLIRKHQRDEIIEELVKSYLKADKDVDA
What are the official names of this protein?
UPF0297 protein lp_2275.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: HRCA_RHIL3
Sequence: MGIRSTSVSDAVAALDERSREIFRRIVEGYLESGEPLGSRNLSRILPMSLSPASVRNVMSDLEELGLIYSPHVSAGRLPTQIGLRFFVDAFMQVGDLSAEERASIDRQVRVESGGNPVESMMNEASRMLSGISRGAGLVITSKSDPVLKHVEFIRLEPTKALAVLVGDHDQVENRIIELPAGVTSSQLTEAANFLNAHMSGQTLPELRKQLSRLKDDVRHELDALSRDLVERGIAVWAGSPDEGKPTQLIIRGRANLLEGLAGAEDLDRLRLLFDDLEKKDSLIEILNLAESGSGVRIFIGSENKLFSLSGSSLIVAPYRDDDDRIVGAVGVIGPTRLNYSRIVPMVDYTAQLVSRLSRSQL
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.