PharMolix/UniProtQA huggingface dataset:
Protein: ISPH_SYNP2
Sequence: MDTKAFKRSLNHSENYYRQGFGHKDEVAGMMTSEYQSSLIQEIRDNNYELTRGDVTIYLAEAFGFCWGVERAVAMAYETRKHFPTEKIWVTNEIIHNPSVNNRLKEMNVHFIEVVDGDKDFSGVANGDVVILPAFGATVQEMQLLNDRGCTIVDTTCPWVSKVWNSVEKHKKKNYTSIIHGKYKHEETVATSSFAGTYLVLLNLEEAEYVRNYILHGGDRQTFLDKFKNAYSEGFDPDKDLDRVGVANQTTMLKSETEQMGKLFEQTMLEKFGPTEINDHFMSFNTICDATQERQDAMFDLVEKDLDLMVVIGGFNSSNTTHLQEIAVERNIPSYHIDSGDRLLGNNVIAHKPLDGEITTQTHWLPAGKLKIGVTSGASTPDKVVEDVIAKIFAEKAQPAALV
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NCPR_ASPFU
Sequence: MAQLDTLDIVVLVVLLVGSVAYFTKGSYWAVPKDPYAAANSAMNGAAKTGKTRDIIQKMEETGKNCVIFYGSQTGTAEDYASRLAKEGSQRFGLKTMVADLEDYDYENLDKFPEDKIAFFVLATYGEGEPTDNAVEFYQFITGEDVAFESGASAEEKPLSSLKYVAFGLGNNTYEHYNAMVRHVDAALTKLGAQRIGTAGEGDDGAGTMEEDFLAWKEPMWAALSESMNLQEREAVYEPVFSVIEDESLSPEDDSVYLGEPTQGHLSGSPKGPYSAHNPYIAPIVESRELFTAKDRNCLHMEIGIAGSNLTYQTGDHIAIWPTNAGVEVDRFLEVFGIEKKRHTVINIKGLDVTAKVPIPTPTTYDAAVRFYMEICAPVSRQFVSSLVPFAPDEESKAEIVRLGNDKDYFHEKISNQCFNIAQALQNITSKPFSAVPFSLLIEGLNRLQPRYYSISSSSLVQKDKISITAVVESVRLPGASHIVKGVTTNYLLALKQKQNGDPSPDPHGLTYAITGPRNKYDGIHVPVHVRHSNFKLPSDPSKPIIMVGPGTGVAPFRGFIQERAALAESGKDVGPTILFFGCRNRNEDFLYKEEWKVYQEKLGDKLKIITAFSRETAKKVYVQHRLQEHADLVSDLLKQKATFYVCGDAANMAREVNLVLGQIIAKSRGLPAEKGEEMVKHMRSSGSYQEDVWS
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes.  It can also provide electron transfer to heme oxygenase and cytochrome B5.  Involved in ergosterol biosynthesis.
What are the official names of this protein?
NADPH--cytochrome P450 reductase, CPR, P450R.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Mitochondrion outer membrane; Single-pass membrane protein; Cytoplasmic side. Cell membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: Y539_BACCR
Sequence: MGRKWNNIKDKKASKDANTSRIYAKFGREIYVAAKQGEPDPESNQALRVVLERAKTYNVPRTIIDRAVEKAKGGSEENYDELRYEGFGPNGAMVIVDTLTNNVNRTAADVRAAFSKNSGNMGVNGSVAYMFDATAVIGLEGKTSDEVLEILMEADVDARDILEEEDSVIVYAEPDQFHAVQSALKGAGVEEFTVAELTMLAQSDVTLPEDAQAQFEKMVDALEDLEDVQQVYHNVDLGE
What are the official names of this protein?
Probable transcriptional regulatory protein BC_0539.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM2S_SOLLC
Sequence: MAEILLTSVINKSVEIAGNLLIQEGKRLYWLKEDIDWLQREMRHIRSYVDNAKAKEAGGDSRVKNLLKDIQELAGDVEDLLDDFLPKIQRSNKFNYCLKTSSFADEFAMEIEKIKRRVVDIDRIRKTYNIIDTDNNNDDCVLLDRRRLFLHADETEIIGLDDDFNMLQAKLLNQDLHYGVVSIVGMPGLGKTTLAKKLYRLIRDQFECSGLVYVSQQPRAGEILLDIAKQIGLTEQKIKENLEDNLRSLLKIKRYVILLDDIWDVEIWDDLKLVLPECDSKVGSRMIITSRNSNVGRYIGGESSLHALQPLESEKSFELFTKKIFNFDDNNSWANASPDLVNIGRNIAGRCGGIPLAIVVTAGMLRARERTEHAWNRVLESMGHKVQDGCAKVLALSYNDLPIASRPCFLYFSLYPEDHEIRAFDLINMWIAEKFIVVNSGNRREAEDLAEDVLNDLVSRNLIQLAKRTYNGRISSCRIHDLLHSLCVDLAKESNFFHTAHDVFGDPGNVARLRRITFYSDNVMIEFFGSNPKLEKLRVLFCFTKDPSIFSHMACFDFKLLHTLVVVMSQSFQAYVTIPSKFGNMTCLRYLKLEGNICGKLPNSIVKLTRLETIDIDRRSLIQLPSGVWESKHLRHLCYRDYGQACNSCFSISSFYPNIYSLHPNNLQTLMWIPDKFFEPRLLHRLINLRKLGILGVSNSTVKILSTCRPVPKALKVLKLRFFSDPSEQINLSSYPKIVKLHLNVDRTIALNSEAFPPNIIKLTLVCFMVDSCLLAVLKTLPKLRKLKMVICKYNEEKMALSGEANGYSFPQLEVLHIHSPNGLSEVTCTDDVSMPKLKKLLLTGFHCGISLSERLKKLSK
What is the function of this protein?
Potential inhibitor of viral mouvements which may confer resistance to some tobamoviruses but not to the tomato mosaic virus (ToMV) and tobacco mosaic virus (TMV).
What are the official names of this protein?
ToMV susceptible protein tm-2, Disease susceptible protein tm-2.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNH22_METPP
Sequence: MRSRKSSRAEAPGLPTDRQLGLSWDVPGLLAGVDEAGRGPLAGPVVAAAVILDDVQPIRGLGDSKVLSERVRERLFDEIRAKALCCCIAEASVEEIDTLNILQATLLAMRRAVAGLRLRPNKVLVDGNRLPVLQVPAEAIVKGDAKVAAISAASILAKVHRDRLCLALHEAHPQYGFAGHKGYPTPDHLAALRVHGACGAHRRSFAPVREVLLERRP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII 2, RNase HII 2.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_HYDS0
Sequence: MAKKLTATVELMLPAGQATPAPPVGPALGQHGINIMEFVKQFNAASKDMEPGTIVPVVISIYADRSFTFIMKTPPTSFLLKKAAKVQKGSSDPKRQKAGKITLNQLKEIAQLKAKDMNTQDLDAVMRTIAGTARSMGIEIEGYKG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: AGO4B_ORYSJ
Sequence: MDAHDGEADELPPPPPVPANVVPIKADDVESEVPANKPAKPKRFPMARPGLGRKGQPIQLLANHYKVSVKSSEEYFFHYNVILKYEDDRPVDGKGVGRKVIDKLQQTYRSELSSKDFAYDGEKSLFTIGALPQVTNEFTVVLEDVSTGKTAANGSPGGNDSPGGSDRKRVRRPYQTKTFKVELCFAAKIPMNAIAQAIKGQESENSQEALRVLDIILRQHSAKQGCLLVRQSFFHNNPNNFVDLGGGVMGCRGFHSSFRGTQSGLSLNIDVSTTMIVKPGPVIDFLLANQKVDHPDRIDWQKAKRALKNLRIRTTPVNSEFKIIGLSDRNCNEQMFSLRQRNGNNGDVDEVEVTVYDYFVKNKGIELRYSGNLPCINVGKPKRPTYFPIELCSLIPLQRYTKALSTLQRSSLVEKSRQKPQERMSVLNDALRHSNYDSDPMLRASGISIAQNFTQVEGRVLQPPKLKAGNGEDIFPRNGRWNFNNKKLIQTCSVDKWAVVNFSARCDVRNLIRDLIRNASAKGIQMAEPFDVFEESPSLRRAPVSRRVDDMFEQIKSKLPGAPKFLLCLLPERKNCEVYGPWKRKCLAEFGIVTQCLAPQRVNDQYLLNLLLKINAKLGGINSLLQIEASPSIPLVSKTPTIILGMDVSHGQPGQSDRPSIAAVVSSRQWPLISKYRASVHTQSPKLEMMSSLFKPRGTEDDGLIRESLIDFYTSSGKRKPDHVIVFRDGVSESQFTQVINIELDQIIEACKFLDEKWSPKFTVIVAQKNHHTKFFQSGSPDNVPPGTVVDKQVCHPRNYDFYMCAHAGMIGTTRPTHYHVLHDEIGFSPDDLQELVHSLSYVYQRSTTAISVVAPICYAHLAAAQVGTFLKFEDMSDASSSQGGHTSVGSVPVPELPRLHEKVRSSMFFC
What is the function of this protein?
Probably involved in the RNA silencing pathway.  May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity).
What are the official names of this protein?
Protein argonaute 4B, OsAGO4b.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
Protein: ETFA_HUMAN
Sequence: MFRAAAPGQLRRAASLLRFQSTLVIAEHANDSLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAATSGGSASSEKASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK
What is the function of this protein?
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase (PubMed:27499296, PubMed:15159392, PubMed:15975918, PubMed:9334218, PubMed:10356313).  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (PubMed:9334218).  Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism (PubMed:12815589, PubMed:1882842, PubMed:1430199).
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: PSBD_CROS5
Sequence: MTIAVGRAPERGWFDVLDDWLKRDRFVFVGWSGLLLFPCAYLALGGWLTGTTFVTSWYTHGLASSYLEGCNFLTVAVSSPANAFGHSLLFLWGPEAQGDFTRWCQIGGLWTFTALHGAFGLIGFMLRQFEIARLVGIRPYNAIAFSAPIAVFVSVFLMYPLGQSSWFFGPSFGVAGIFRFILFLQGFHNWTLNPFHMMGVAGVLGGALLCAIHGATVENTLFEDGEQANTFRAFEPTQAEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWMSAIGIVGLALNLRAYDFVSQELRAAEDPEFETFYTKNILLNEGLRAWMAPQDQPHQNFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PGSA_YERPA
Sequence: MQLNIPTWLTLFRVVLIPFFVLAFYLPFVWAPMVCAIIFVFAAATDWFDGFLARRWKQTTRFGAFLDPVADKVMVAVALVLVAEHYHSWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWVGKVKTMAQMGSLVGLLWRPDHNVELASFVLLYIAAVLTFWSMFQYLNAAWSDLLEP
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YQGF_VIBCM
Sequence: MSRTVMAFDYGTKSIGSAIGQEITGTASPLKAFKANDGIPNWDEIEKQIKEWQPNLLIVGLPTDLHGKDLDTITPRAKKFAQRLHGRFGLPVELHDERLSTTEARAELFAMGGYKALSKGNVDCQSAVIILESWFESQWG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAT_ECOLC
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLISTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKSLIIHNVLLSTLGGLMWYLQFFFYAWGHAPIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMD_BART1
Sequence: MKFQARVLTLYPEMFPGFLGYSLAGHALERGIWSLETVQIRDFALDKHHSVDDTPAGGGAGMVMRADVLAAALDHCPQDSPRLLMSPRGRPFDQAYARRLADDSGITLVCGRFEGVDERVIEARELEEVSIGDYILSGGETAALVILDAIIRLLPGVMGNKASAKCESFENGLLEHPQYTRPSLFEGREIPPVLTSGHHKAIADWRQSQAELLTRQRRPDLYARYDKNRQKT
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_ACIBY
Sequence: MQRYAVGIEFSGIQYRGWQTQQPGVASVQETIERVLSKIADEPITLHGAGRTDAGVHATNMVAHFDTTAIRPERGWIMGANSQLPKDISIQWIKQMDEEFHARFKATARRYRYVVYNAPHRPALLHKQVTHIYQKLDVQKMIKAASKFEGTHNFETFRAAACQSNQPVRHVKHCRLFQHGRYLVLDIQADGFLHHMVRNIMGCLLEIGQGMYEIDHIDTMFAAEDRKAAGITAPPDGLYFIQCYYPEQFDLPQPPLGPHWLNLPE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: STX7B_DICDI
Sequence: MTDRQPLISKNDDIINNLTRFYTELTEFEKIIKDVGTGRDTTTLRSTLHKKKVNLADDLKVIAQQIKQLPSSKLPKFQQEKIVKQFKEASSKFEELLSTSNKKESSHEPIVPSQQQQQQQNNGNSNNNGYNTRGGYNQQQQQQQQQYNDYTNNNNNNNNNEVEQYNRLEQALKSGIEQDEEEYTNRILDERNANARQIARDVAMLKEAMDDIAVMVGEQGEMLEKVDDNVTNADVAVEDAVVELEKAYVYKSSYRKKMIIFVICLLVTLVAVGIFLAIYYGVIKKK
What are the official names of this protein?
Probable syntaxin-7B.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATG7_DEBHA
Sequence: MSSVSASTERKHIKFTPIQSFVESSFFTKLSELKLDEFKLDSTKKEIKGFLTHPKRLNKFNDYPTINFDYSSFDKGPDVNEDNNISWKGYIYNVNTIEEFKDIDKQAILKRWGTEIYNEIQDGSVDLSYECFNKVHVLAFCDLKKYKFYYWFAFPTLHSPWNIIGADGDSLKKFIPSIKEFVETSKFVQFFQINDGNIIERVSEFQESKIFVFIDTCLSQACTPSVQLKNYLYVLARKGFENIDLIIYRNNGNSFYWKLQLDKDKLGINEVPRISGWERLSNGKLGPRLADLGSLIDPQELAKQAVDLNLKLMKWRIAPNLDLDIIKNQRVLLLGAGTLGSYVSRALMGWGVRNITFVDNGRISYSNPVRQPLFSFKDCFSDEGQGEWKAIRAANTLKEIFPDVQSKGYNLEVPMIGHPVNNETKQKSSFDKLSDLFDDHDVVFLLMDSRESRWLPTVLGLAKNKIVLNAALGFDSFLVMRHGNISNANNDDTRVGCYYCNDVVAPNDSLSDRTLDQMCTVTRPGVALMASSLAVELFISMLQHPNKQYAEPGPSNNLILGEVPHQIRGFLHNYSQSKLQTPNYKHCSACSKYVIDKFNELGWEFVKNCLNDVTYLEETCGLLKVQQEADLASSELLKDLELSDDDDSEWLD
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.  Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine.  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: TVB66_HUMAN
Sequence: MSISLLCCAAFPLLWAGPVNAGVTQTPKFRILKIGQSMTLQCAQDMNHNYMYWYRQDPGMGLKLIYYSVGAGITDKGEVPNGYNVSRSTTEDFPLRLELAAPSQTSVYFCASSY
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 6-6.
What are the subcellular locations of this protein?
Cell membrane.
Protein: Y1216_METJA
Sequence: MPKRDIKAFLYDILEYMDDIINFTKNMEYEEFINNKAIKYAVVRCLEVIGEAVKKIPKDIREKYPHIPFKELAGMRDKLIHQYFGVDYLTVWETAKYEIPEIKKEFEKIIKDIEGKDENSL
What is the function of this protein?
Probable toxic component of a putative type VII toxin-antitoxin (TA) system, probably an RNase.  Probably neutralized by antitoxin MJ1215 or MJ1217.  Neutralization may be due to AMPylation by antitoxin.
What are the official names of this protein?
Putative RNase MJ1216, Putative toxin MJ1216.
What is the protein family that this protein belongs to?
Belongs to the HepT RNase toxin family.
Protein: DOR_ARATH
Sequence: MKSRRQNVSVARQTILGRDENFEPIPIDLVIEIFSRSPVKSIARCRCVSKLWASILRLPYFTELYLTKSCARPRLLFACQKHRELFFFSTPQPHNPNESSSPLAASFHMKIPFDGRFNIISPIGGLVFVRYEQILKGRKTPEFVSAICNPSTGQSLTLPKPKTRKRIWGTSHFGYDPIEKQFKVLSMNIGDGVYKEHYVLTLGTENLSWRRIECSIPHVHGSKGICINGVLYYRAKADMFSGTLMIVCFDVRFEKFSYIKILKPTTTLISYNGKLASLVWEGPSYICGKRFEMWVLGDPEKHEWLKHTYELRPRWQNVLGEDLLIFAGMTGTNEIVLSPKYPSHPFYVFYYNLERNTIRRVEIQGMGAFKVNEDYIFLDHVEDVKLI
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Negative regulator of guard cell abscisic acid (ABA) signaling, especially during drought stress.
What are the official names of this protein?
F-box protein DOR, Protein DROUGHT TOLERANCE REPRESSOR.
Protein: RL33_ECOSE
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TSAD_METEP
Sequence: MKILGIETTCDETAAAVVTLGEDERGQILANEVLSQIAEHAAYGGVVPEIAARAHVEVLDRLIARALQRAGTTLKEIDGIAVAAGPGLIGGVLIGLVTAKTLALVARKPLLAVNHLEAHALTPRLTDGLAFPYLLLLASGGHTQLVAVKGVGDYVRLGTTIDDAIGEAFDKVAKLLGLGYPGGPEVERQAESGNPERFALPRPMIGRRQADFSLSGLKTALRIEAERLEPLASQDVADLCASFQAAVVDVVVDRVRVALRAFAGVAGHPTALVAAGGVAANGAIRRALAAQAGEVGLSFVAPPLPLCGDNGAMIAWAGLERLRLGLVDDLTVPARARWPFAEVAPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPRR_RAT
Sequence: MRRAVGFPALCLLLNLHAAGCFSRNNDHFLAIRQKKSWKPMFIYDHSQDIKKSLDIAQEAYKHNYPAPSEVQISKRHQIVDSAFPRPAYDPSLNLLAASGQDLEIENLPIPAANVIVVTLQMDIDKLNITLLRIFRQGVAAALGLLPQQVHINRLIEKKSQIELFVSPGNRKPGEPQALQAEEVLRSLNVDVLRQSLPQFGSIDVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFIIIVTCLMIIYRLKERLQLSFRQDKEKNQEIHLSPIALQQAQSEAKAAHSMVQPDQAPKVLNVVVDPQGQCTPEIRNTASTSVCPSPFRMKPIGLQERRGSNVSLTLDMSSLGNVEPFVAVSTPREKVAMEYLQSASRVLTSPQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNITDPLSTYINANYIRGYSGKEKAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVIGVNECDNYTIRNLVLKRGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASEGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFESRLSPETVQ
What is the function of this protein?
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form.  The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase R, R-PTP-R, PC12-PTP1, Protein-tyrosine phosphatase PCPTP1, Tyrosine phosphatase CBPTP.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
What are the subcellular locations of this protein?
[Isoform 3]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane; Single- pass type I membrane protein.
Protein: G1L7_ORYSI
Sequence: MDPSGPGPSSAAAGGAPAVAAAPQPPAQLSRYESQKRRDWNTFLQYLRNHRPPLTLARCSGAHVIEFLRYLDQFGKTKVHASGCAFYGQPSPPGPCPCPLRQAWGSLDALIGRLRAAYEESGGTPESNPFAARAVRIYLREVRDSQAKARGIPYEKKKRKRSQAAQPAGVEPSGSSSAAAAAAGGGDTGSGGGAAATTTAQPGGSGTAPSAS
What is the function of this protein?
Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light.
What are the official names of this protein?
Protein G1-like7.
What is the protein family that this protein belongs to?
Belongs to the plant homeotic and developmental regulators ALOG protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIG_CHLMU
Sequence: MFSINIEETAGCVVSAKVQANPLVTQKCHKEALKTVKKNVVLPGFRKGKAPDNIIEARYATQVEQELRRFLLRASFEALSQMCDRKPLSPKAVRSSTVDSCNAADGGVVSFLYEAFPVIPSLPWEQLNLSDPEPVKEISDEDLENGLKNVAYFFATKTPVTRPSQEGDFISLSLHVSKKGDLNSNPVAIFENKYFKISEEDMTDAFKARFLNVSTGHRVEEEIASEDIQSFLNGDLLTFTVNAVIEISSPEMDDEKARQLQAESLEDLKKKLRIQLENQAKEEHHQKRFSAAEDALAQLIDFDLPQSLLQEREEILSREKLLNARLVKYCSDSELEEQKQTLLEEAKADARKAVKLLFLTQKVFSEKELSISREELQRMMDVCSRERFGAHPPKDISNEMLQELVLAARDRLTYHKAIEAISAEKKDLEVVPS
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: BL1S5_DICDI
Sequence: MNPKDKRVNFGSMEPLIRDIGTVYEFYFDQNTFIESEIKTFLKEFETKRGDRDLYSLSQQTINANNTIVNINRSIHQSSQFLENINNNLNQINSKLSTQVENESIHQEQRNNDRLNKFELELVEKKSIEDSFNQRKSQIENDFNEKASVLRDKYQIVL
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).  May play a role in intracellular vesicle trafficking (By similarity).
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 5, BLOC-1 subunit 5, Protein Muted homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S5 family.