PharMolix/UniProtQA huggingface dataset:
Protein: STAB2_RAT
Sequence: SLPSLLTRLEQMPDYSIFRGYIIHYNLASAIESADAYTVFVPNNEAIENYIREKKATSLKEDILRYHVVLGEKLLKNDLHNGMHRETMLGFSYLLAFFLRNDQLYVNEAPINYTNVATDKGVIHGLEKVLEIQKNRCDNNDTIIVRGECGKCSQQAPCPLETKPLRETRKCIYSIYFMGKRSVFIGCQPQCVRTIITRACCAGFFGPQCQACPGRGQNVCSGNGFCLDGVNGTGTCQCGLGFNGTACETCTEGKYGIHCDQACSCVHGRCSQGPLGDGSCDCDVGWRGVKCDMEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFRGNGTVCTAINACETSNGGCSTKADCKRTTPGNRVCVCKAGYTGDGIVCLEINPCLENHGGCDRNAECTQTGPNQAVCNCLPKYTGDGKVCSLINVCLTNNGGCSPFAFCNYTEQDQRICTCKPDYTGDGIVCRGSIYGELPKNPSTSQYFFQLQEHAVRELAGPGPFTVFAPLSSSFNHEPRIKDWDQQGLMSQVLRYHVVGCQQLLLDNLKVTTSATTLQGEPVSISVSQDTVFINNEAKVLSSDIISTNGVIHVIDKLLSPKNLLITPKDALGRVLQNLTTVAANHGYTKFSKLIQDSGLLSVITDSIHTPVTVFWPTDKALEALPPEQQDFLFNQDNKDKLKSYLKFHVIRDSKALASDLPRSASWKTLQGSELSVRCGTGSDIGELFLNEQMCRFIHRGLLFDVGVAYGIDCLLMNPTLGGRCDTFTTFDIPGECGSCIFTPKCPLKSKPKGVKKKCIYNPLPFRRNVEGCQNLCTVVIQTPRCCHGYFMPDCQACPGGPDTPCNNRGMCRDLYTPMGQCLCHTGFNGTACELCWHGRFGPDCQPRSCSEHGQCDEGITGSGECLCETGWTAASCDTPTAVFAVCTPACSVHATCTENNTCVCNLNYEGDGITCTVVDFCKQNNGGCAKVAKCSQKGTQVSCSCKKGYKGDGYSCIEIDPCADGVNGGCHEHATCRMTGPGKHKCECKSHYVGDGVDCEPEQLPLDRCLQDNGQCHPDASCADLYFQDTTVGVFHLRSPLGQYKLTFDKAKEACAKEAATIATYNQLSYAQKAKYHLCSAGWLESGRVAYPTTYASQKCGANVVGIVDYGSRANKSEMWDVFCYRMKDVNCTCKAGYVGDGFSCSGNLLQVLMSFPSLTNFLTEVLAFSKSSARGQAFLKHLTDLSIRGTLFVPQNSGLPGNKSLSGRDIEHHLTNVNVSFYNDLVNGTFLRTMLGSQLLITFSQDQLHQETRFVDGRSILQWDIIAANGILHIISEPLRAPPTAATAAHSGLGTGIFCAVVLVTGAIALAAYSYFRLKQRTTGFQRFDQKRTLMSWLLASSSPRISQTLCMRPQRRHPQSPPVTPSQTLENRIWRTATLWGHCGPDMRSQQATTVTVPR
What is the function of this protein?
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells.  Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA).  Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE).  May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan.  Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature.  Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection.  The proteolytically processed 175 kDa form also functions as an endocytosis receptor for heparin internalization as well as HA and CS.
What are the official names of this protein?
Stabilin-2, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2, FEEL-2, Hyaluronan receptor for endocytosis.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Single-pass type I membrane protein.
Protein: KDXD_HALVD
Sequence: MHYHQLAVSGERRLTASRDSTTYDLTSADADLRTFGDLARVASIARTSVDRLAAELTEDADVVDDAFVDRHATVPVDAEEIWAAGVTYQISEQAREEESSMPDMYFDVYDADRPEVFFKATPSRTVEPGDAIGVRGDSEWDVPEPELGIVLRRGEIVGYTVGNDVSSRSIEGENPLYLPQAKVYDRCCSIGPCVVTPEDVEDPHELEMSMTIERDGEVIYDDATNTSEMVRSCDELVSYFTRHNTVPELAVILTGTSLVPEQPFDLQEGDHVDITIEGIGTLSNSVTTV
What is the function of this protein?
Probable 2-keto-3-deoxyxylonate dehydratase involved in the degradation of D-xylose, a major component of hemicelluloses such as xylan.  Catalyzes the fourth reaction in the xylose utilization pathway through dehydratation of 2-dehydro-3-deoxy-D-xylonate into alpha-ketoglutarate semialdehyde (2,5-dioxopentanoate).
What are the official names of this protein?
Probable 2-keto-3-deoxyxylonate dehydratase, KDXD.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: TPP1_PONAB
Sequence: MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQHPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDEEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFLEPFLTTNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTHGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALPKTLLNP
What is the function of this protein?
Lysosomal serine protease with tripeptidyl-peptidase I activity.  May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases.  Requires substrates with an unsubstituted N-terminus (By similarity).
What are the official names of this protein?
Tripeptidyl-peptidase 1, TPP-1, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, TPP-I.
What are the subcellular locations of this protein?
Lysosome. Melanosome.
Protein: MNMG_GLUDA
Sequence: MTTEYDVIVIGGGHAGCEAAAAAARCGARTLLLTHRRDTIGAMSCNPAIGGIGKGHLVREIDALDGLMARAADRAGIHFKLLNRSKGPAVHGPRAQADRSLYRRAIQDLLAETANLDIAEGAAGDLIVDDAGQAAGVVCEDGRQFRAGAVVLTAGTFLRGVIHIGHDSHPAGRVGEPPAHALGERLQALGLPMGRLKTGTPARLDRTSIDWDSLAEDRGDAVPEPFSRLTQAIDNPQLSCRITATTPRTHALIREHLHLSAVYGGAIAGRGPRYCPSIEDKVVRFAERDSHQIFLEPEALPGNAGGDLVYPNGISTSLPADIQEQLIHSIPGLERCRIVRPGYAVEYDYVDPRALAPTLELTALPRLFLAGQINGTTGYEEAGAQGLLAGLNAARRAGGGEGIAIDRGAAYLGVMIDDLATQGVSEPYRMFTSRAEYRLSLRADNADLRLTGQGIGWGCVGSARAHLFTAERDAIDTAMQRAGAESFLPDALQQAGITVSADGRRRTLLDVLATAATPDAIARIAPWFAALPSRVSRHVETEARYSGYLVRQAREIRQLEAETRITLPADLDYRRIGGLSSEMQERLAAARPASFSAAQRVPGITPSALMALLSHVRQVA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_PSE14
Sequence: MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRTVQDIRNLLNAGADKVSINTAAVFNPEFVGEAAARFGSQCIVVAIDAKKVSGPGETPRWEIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGMKNGFDLGVTRAISDALGIPVIASGGVGNLEHLAAGVIEGHASAVLAASIFHFGEYTVPEAKAYMASRGIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHR_HUMAN
Sequence: MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRWTWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPFPAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAPFENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLYSIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQQQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFVPFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYPMGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQHTHVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFPDLTSSGFL
What is the function of this protein?
Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer (PubMed:30373764, PubMed:23275542, PubMed:7961644, PubMed:32818467).  Upon ligand binding, translocates into the nucleus, where it heterodimerizes with ARNT and induces transcription by binding to xenobiotic response elements (XRE) (PubMed:30373764, PubMed:23275542, PubMed:7961644).  Regulates a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation (PubMed:12213388).  Xenobiotics can act as ligands: upon xenobiotic-binding, activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene) (PubMed:7961644).  Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons (PubMed:7961644, PubMed:34521881).  Next to xenobiotics, natural ligands derived from plants, microbiota, and endogenous metabolism are potent AHR agonists (PubMed:18076143).  Tryptophan (Trp) derivatives constitute an important class of endogenous AHR ligands (PubMed:32866000, PubMed:32818467).  Acts as a negative regulator of anti-tumor immunity: indoles and kynurenic acid generated by Trp catabolism act as ligand and activate AHR, thereby promoting AHR-driven cancer cell motility and suppressing adaptive immunity (PubMed:32818467).  Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1 (PubMed:28602820).  Inhibits PER1 by repressing the CLOCK-BMAL1 heterodimer mediated transcriptional activation of PER1 (PubMed:28602820).  The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28602820).
What are the official names of this protein?
Aryl hydrocarbon receptor, Ah receptor, AhR, Class E basic helix-loop-helix protein 76, bHLHe76.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.
Protein: SYL_RICFE
Sequence: MNQIEQKWQQIWYDEKAFEVSNESSKPKYYVLEMLPYPSGKIHVGHVRNYSIGDVIARFMTMQGFNVLHPMGWDAFGLPAENAAIKNNSHPKDWTYSNIENMKKQLKSMGFSYDWSREINSCDPQYYKHEQKFFLELYERNLAYQKESLVNWDPVDNTVLANEQVVDGRGWRSGAIVEKRYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEDNTIEVFSTKPETIFGAGFIGIAFNHPIIEKLISKTPEILSFITKCSHITGSSELEKTEKEGVFTGLYVIHPFDSNIVLPVIITNFVLMDYGTGAVFGCPAHDERDHELAVKMNLPIKQVIETDIDVQKTAYTEDGILVNSDFLNGLTSNEAKQKVIDEFEKLGIGKRSVYYRLKDWGISRQRFWGCPIPMIHCEACGIVPVPCSDLPVTLPDDVSFDGHGNPLDHHPSWKHVNCPKCDKSAIRETDTFDTFFESSWYFTRYCNSNATEMTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQNYVSVREPFKGLFTQGMVLHATYKDEHNNWLYPEEVVKKGNEFFHKESNNRVVQGRIEKMSKSKKNLIDLVTMQEQYGADAIRLFVLSDSPPEKDLEWSASGIEGCSRFINKLEHMFEAIASLIDDVNSEINKELNRLVHFTIKHVADDIKHFVLNRAIARMRELSNAISAELNKEVVDVKTVRYGFNVIVQLLNPFIPHITEEIWQKLGNKERLYNSAFPAFDESMLELDTYVMAVQVNGKLRDTYEFKTSASEDEIKQITVNLPKVQKFLEGKEPKKIILVPRKIVNIIV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBBC1_HYAOR
Sequence: ERPLCNECFICDRSGDPRCLCEDHVPQCHEGCHQCEKVDTRSGTTMYQCRSFEYYDCANE
What is the function of this protein?
Serine protease inhibitor (PubMed:33666645).  Strongly inhibits trypsin (Ki = 0. 22 nM) and very weakly inhibits chymotrypsin (Ki = 1200 nM) (PubMed:33666645).  Does not inhibit bacterial subtilisin (PubMed:33666645).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor C1, HOSPI-C1.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: NUDL_ECOBW
Sequence: MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: RL31_SALTY
Sequence: MKKGIHPNYVEITATCSCGNVIKTHSTVGHDLNLDVCGKCHPFFTGKQRVVDTGGRVERFNKRFSIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: YCIU_ESCF3
Sequence: MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEERGGAELFDPSEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDIFARILLCREKDHKLCHILWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: BGAL_MACFA
Sequence: MPGFLVRILPLLLPLLLLGPTRGLRNATRRVFEIAYSQDRFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNTIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKEAILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPIITVQVENEYGSYFACDFDYLRFLQKRFHHHLGDDVVLFTTDGAHETFLQCGALQGLYTTVDFGPGSNITDAFQIQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEVVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNVIQKFEKVPEGPIPPSTPKFAYGKVSLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQYYGFVLYRTTLPQDCSNSTPLSSPFNGVHDRAYVAVDGIPQGVLERNRVITLNITGKTGATLDLLVENMGRVNYGAYINDFKGLVSNLTLDSNILTGWTIFPLDTEDAVRSHLGGWEHRDSGRHDEAWAHSSSNYTLPAFYVGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELERAPCSSDGPELCAVEFVDRPVIGSSQIYDHLSKPVEQRLMAPPPKKTKIRGWSMYDDESL
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
What are the official names of this protein?
Beta-galactosidase, Acid beta-galactosidase, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PYRI_SODGM
Sequence: MTQDNKLQVEAIRRGTVIDHIPAQVGMKLLSLFKLTATDERITIGLNLPSNQQGKKDLIKLENIFLTEEQANQLAIYAPHATVNRIDNYDVVRKQTLSLPERIDGVLTCPNSNCISRSEPVASGFRVQVHGQQVHLQCKYCEKEFEHQAVVQSA
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: AMPA_GEOTN
Sequence: MFTVKPWSSAEVVHEALAIGLFEGKDSWSGLAGEYDSRLGGQLSNLRKEGDISAKRGRIATIHTMLPTGVKRLYFVGLGKKEELTFERLREVFGKLFRTWKQAKRTEAAIALDTFTTETVDSNEAAHALAEAYYLATYEFPGYKQKKSEPDYALESLTVYTAADAAEIEASLFVGSVYGKATNSARTLVNTPGNLLTASDLADYAVELAKRYDFDYEILEKEEMERLGMGALLAVNQGSKQPPKLIVLKYQGKEQWENVIGLVGKGVTFDTGGYCLKPRDSMIDMKTDMGGAAAVLGAMEAIGELRPEQNVLAVIPATDNMISAEAFKPDDVITSLSGKTIEVRNTDAEGRLILADAITYAKQHGARYLIDVATLTGGVIVALGTDKTGAMTNNEALFEQLLEASMETGEFIWRLPITEKDRERVRSSKIADLNNSPGREGHAIMGGAFIGEFAEDTPWVHLDIAGTATTKKDGDLGPAGATGVMVRTLTAFVERFE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Q0182_YEAST
Sequence: MVSGPGHGSRNPERSFIINMKRVRMMMNSFNLFLMKYNFKMVFMVRPAPRGGADPEGVRSGINYNNYINIIIIYYIMMYLFMFYNINNYFMFNKYNMYIIFFNNYTINSYFGGIGRHDTTKMYYFTVWRFKSFK
What are the official names of this protein?
Putative uncharacterized protein Q0182, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DER_CUPMC
Sequence: MKPVIALVGRPNVGKSTLFNRMTRSRDALVADLPGLTRDRHYGEGRIGDRPFIVIDTGGFEPVAKEGIVAEMAKQTRQAVVEADVVIFLVDGRLGLAPQDRVIADYLRKTGRRVMLAINKAEGMKYTSVAADFYELGMGDPYAISSTHGDGVRELVDEALDLAVQERPELADQEDAGQHGVKIAIVGRPNVGKSTLVNTLIGEERVIAFDMPGTTRDAIYVEFERGGKPYTLIDTAGLRKRGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISEQDAHIAGFIVESGRALVVGVNKWDGLDGHQRDRVKHDLERKLQFLSFANIHFVSARERTGIGALLRSVDDAYAAAMIKLPTPQITRVLQEAVEFQQPKRVGVSRPKLRYAHQGGSNPPIIVVHGNALSGVTDAYRRYLENRFRTAFKLKGTPLRIEFRTNKNPYAESKD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: HIS4_LEIXX
Sequence: MSEFNNRPRLVLLPAVDVADGKAVRLTQGAAGSETSYGDPVDAAAEWADAGAEWIHLVDLDAAFGRGDNRGLLKRVIRQTKGVKIELSGGIRDDDSLEHALEIGATRVNLGTAALENPEWASHVIGQYGEAIAVGLDVRGTTLAARGWTREGGDLWQVLERLEEAGCARYVVTDVTKDGALKGPNLDLLRQVVERTERPVVASGGIASLDDIAALRELVSLGVEGAIVGKALYSGAFTLPEALDVAGH
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_RHIL3
Sequence: MTDLKPFLAKAASREPLTREEARSAFDILMSGQATPSQIGGFLMALRVRGETVDEIVGAVASMRSKMLTVEAPADAIDIVGTGGDASGTYNISTLAALIVAGAGVPVAKHGNRALSSKSGAADNLAALGVKLDVGPEIISRCIAEAGVGFMFAQMHHSAMRHVGPSRVELGTRTIFNLLGPLSNPAGVRRQLLGVFSPQWLVPLAEVMRDLGSECVWVVHGDGLDEITTTGITKVAALEDGKIRTFELSPADFGVSPCVLADIKGGDGVANAAALREVLGGAKNAYRDVSLANAAASLVIAGKVETIHDGMTLAAQSLDSGATALALDKLIAVSNDID
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ADH1_RABIT
Sequence: MSTAGKVIKCKAAVLWQLNKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHAVTGSIAVPLPVILGHEAAGIVESIGEGVTTVKPGDKVIPLFTPQCGKCRICKHPESNFCLINDLGKPKGMLLDGTSRFTCKGKPIHHFIGTSTFSQYTVVDEIAVAKIDAAAPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVIMGCKAAGASRIIAVDINKDKFPKAKEVGATECINPQDYKKPIQEVIQEISDGGVDFSFEVIGRLDTVVAALLSCHGACGTSVIVGVPPDSQSLTVNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFSLDPLITNVLPFEKINEGFDLLRSGKSIRTILTF
What are the official names of this protein?
Alcohol dehydrogenase 1, Alcohol dehydrogenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APIBP_RHIEC
Sequence: MKLTRRLTLAAFASALALGTAMPAFAADLIAIITPAHDNPFFKAEAVGAEAKAKELGYETLVMTHDDDANKQSEMIDTAIGRGAKAIILDNAGADASVAAVKKAKDAGIPSFLIDREINATGVAVAQIVSNNYQGAQLGAQEFVKLMGEKGNYVELVGKESDTNAGIRSQGYHDVIDDYPEMKSVAKQSANWSQTEAYSKMETILQANPDIKGVISGNDTMAMGAIAALQAAGRKDVIVVGFDGSNDVRDSIKSGGIKATVLQPAYAQAQLAVEQADAYIKNKTTPKEEKQLMDCVLINADNAGKLETFALTN
What is the function of this protein?
Part of an ABC transporter complex involved in D-apiose import (Probable).  Binds D-apiose, D-ribose and D-ribulose (PubMed:29867142).
What are the official names of this protein?
D-apiose import binding protein, D-apiose binding SBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PRIA_HELPJ
Sequence: MFYHLIAPLKNKTPPLTYFSKERHLKGALVNIPLRNKTLLGVVLEEVSKPSFECLELEKTPYFLLPFQIELAIFIAQYYSANLSSVLSLFAPFKECDLVGLEKIEPTLNALSQTQTNALKELQKHPASLLFGDTGSGKTEIYMHAIAQTLEQKKSALLLVPEIALTPQMQQRLKKVFKENLGLWHSKLSQNQKKQFLEKLYSQEIKLVVGTRSALFLPLKELGLIIVDEEHDFSYKSQQSPMYNARDLCLYLSHKFPIQVILGSATPSLSSYQRFKDKALVRLKGRYTPTQKNIIFEKTERFITPKLLEALKQVIDKNEQAIIFVPTRANFKTLLCPNCYKSVQCPFCSVNMSLHLKTNKLMCHYCHFSSPIPKICNACQSEVLVGKRIGTMQVLKELESLLEGAKIAILDKDHTSTPKKLHNILNDFNAQKTNILIGTQMISKGHDYAKVSLAVVLGIDNIIKSNSYRALEEGVSLLYQIAGRSARQISGQVFIQSTETDLLENFLEDYEDFLQYELQERCELYPPFSRLCLLEFKHKNEEKAQQLSLEASQTLSLCLEKGVTLSNFKAPIEKIASSYRYLILLRSKNPLSLIKSVHAFLKTAPNIPCSVNMDPVDIF
What is the function of this protein?
Involved in the restart of stalled replication forks.  Recognizes and binds the arrested nascent DNA chain at stalled replication forks.  It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
What are the official names of this protein?
Primosomal protein N', ATP-dependent helicase PriA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PriA subfamily.
Protein: RS23_PAPDA
Sequence: MGKPRGIRTARKHVNHRREQRWADKDYKKAHMGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPRDGCLNHIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRS
What are the official names of this protein?
40S ribosomal protein S23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: RL31B_ECOSM
Sequence: MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RS12_PARDP
Sequence: MPTIQQLIRKPRQPKVQRSKSQHLQSCPQKRGVCTRVYTTTPKKPNSAMRKVAKVRLTNGFEVISYIPGEKHNLQEHSVVLIRGGRVKDLPGVRYHILRGVLDTQGVKDRRQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL3_STAS1
Sequence: MTKGILGRKIGMTQVFGENGDLIPVTVVEASQNVILQKKSEEIDGYNAIQVGYEDKQAYKKDSRSSKYANKPAEGHAKKAGTAPKRFIREFRNVNVDEYEVGQEVSVNTFEAGDVIDVTGVSKGKGFQGAIKRHNQARGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQIDAENNVILVKGNVPGPKKGFVEITSSIKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ATP6_ACIB3
Sequence: MAAEEHALTSTEYIKHHLTNMTYGKMPDGTWKLAETAEEAHSMGFTAIHLDSMGWSIGLGVIFCLLFWIVARAANAGVPTKFQSAIEMIIEFVDSSVRDTFHGKSRLIAPLALTIFVWIFLMNLMDLIPVDWIPQVAAFVGANVFGMDPHHVYFKIVPSTDPNITLGMSLSVFVLILFYSIREKGVGGFVGELALNPFNPSNPVAKALLIPVNLILELVTFLARPISLALRLFGNMYAGELIFILIALLPFWIQWALSVPWAIFHILVITLQAFIFMMLTIVYLSMASEKH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y716_METJA
Sequence: MEFYNIGDIMALKFTIEELSNQKRDTLGRNIDVTVFRLIRFMDLERYLGRGAHGVIYECGRELGLALNPKTVEDVVKFCEEYKIGKVEIVNKEPL
What are the official names of this protein?
Uncharacterized protein MJ0716.