PharMolix/UniProtQA huggingface dataset:
Protein: TRIM1_MOUSE
Sequence: MGESPASAVLNASAGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPSSAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVSDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPQLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNCRPQESPYVSGMKACH
What is the function of this protein?
E3 ubiquitin ligase that plays a role in microtubule stabilization.  Mediates the 'Lys-48'-linked polyubiquitination of LRRK2 to drive its localization to microtubules and its proteasomal degradation in neurons.  This ubiquitination inhibits LRRK2 kinase activation by RAB29.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase MID2, Midline defect 2, Midline-2, RING-type E3 ubiquitin transferase MID2, Tripartite motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
Protein: UD2A2_MOUSE
Sequence: MIKKVLQLLIFHLTLAEIVLSGNVVVWPTDGSHWLNIKILLEELVQRNHSVTVLAPSETLFINSRLDAFINFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMERLQKGGFDVLLADPVTMCGELVALKLGIPFVYTLRFSPAFTVERHCGKIPAPISYVPAALSELTDQMSFGERVKNIISYSLQDYIFKTYWGEWNSYYSKVLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGKTGKKKKRD
What is the function of this protein?
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile.  Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds.  Catalyzes the glucuronidation of endogenous estrogen hormone estradiol.  Contributes to bile acid (BA) detoxification by catalyzing the glucuronidation of BA substrates, which are natural detergents for dietary lipids absorption.  Potential role in detoxification of toxic waste compounds in the amniotic fluid before birth, and air-born chemical after birth.
What are the official names of this protein?
UDP-glucuronosyltransferase 2A2, UDPGT 2A2, UGT2A2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: HIS4_FRAAA
Sequence: MAGVTLTLLPAVDVADGRAVRLVQGEAGSETSYGDPLEAALTWQRDGAEWIHLVDLDAAFGRGSNRELIAEVVRSVDVAVELSGGIRDDDSLDAALATGAARVNIGTAALEDPDWVRRAIDRVGDRIAVGLDVRGTTLAARGWTQDGGELFEVLARLDADGCARYVVTDVRRDGTLTGPNVELLRSVTAVTDRPVVASGGVSALADLVAIAAVPGVEGAIVGKALYAGAFTLPEALAVTSTVVAG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM125_HUMAN
Sequence: MSEQEAQAPGGRGLPPDMLAEQVELWWSQQPRRSALCFVVAVGLVAGCGAGGVALLSTTSSRSGEWRLATGTVLCLLALLVLVKQLMSSAVQDMNCIRQAHHVALLRSGGGADALVVLLSGLVLLVTGLTLAGLAAAPAPARPLAAMLSVGIALAALGSLLLLGLLLYQVGVSGHCPSICMATPSTHSGHGGHGSIFSISGQLSAGRRHETTSSIASLI
What are the official names of this protein?
Transmembrane protein 125.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYS_HYPBU
Sequence: MTWSILRYLRENPDILKDSMRKRGLDPSVIDEAKRVDEEWRKLKRQVDEIRHRHNVITRQIASARDPEERRKLIEEARRLLAEREELEKKLKALEEERERILLSLPNIVHDSVPVGFSDEENVPIRFWGRPRVYRGHLDAFKAQTERWGFKVDYELIDWKPVGHADMLEYVLKLGNTMKAAEVAGSRFYYLFDDIVWLDFALLLYAIDRLTQKGYRLVLPPYMIRHKILMGVIDMETFKDAIYKVEDEDLYLIATAEHPLAGLYYNEEIMEDELPIKLVGISPCFRKEAGAGNRDLKGIFRVHQFHKVEQFVYAKPEESWDILEELIRNAEELFQGLGLPYRVVNVVSGELGAPAAKKYDLEVWMPAQGKYREMVSASNTTDWQSYRLNIRLVRKKDMKREYVHTLNSTAIASTRTITAILENFQEPDGTVVIPKVLRKYLEIFPKAPKDAIHPVKKVRG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_PSEPK
Sequence: MMDFWTAFQAIILGVVEGLTEFLPISSTGHQIIVADLIGFGGERAMAFNIIIQLAAILAVVWEFRSKIFEVVFGLTNQPKARRFTGNLLLAFMPAVVLGVLFADLIHEYLFNPVTVAAALVVGGVIMLWAERREHRVEVDHVDDMRWSHALKIGFIQCLAMIPGTSRSGSTIIGGLLFGLSRKAATEFSFFLAMPTMVGAAVYSGYKYRDLFQPGDLPVFALGFVTSFIFAMIAVRALLKFIANHSYAAFAWYRIVFGLFILATWQFGWVDWSTAHG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EXOL4_ARATH
Sequence: MAYNYRFAILLVLLSATVGFTAAALKPPVRTLNGNITLNLIWYGKFTPIQRSIIVDFIRSISSVTAAKGPSVASWWKTTEKYKTGVSTLVVGKQLLLENYPLGKSLKSPYLRALSSKLNAGGARSITVVLTAKDVTVEGLCMNRCGTHGSKSSSVNSGAYVWVGNSETQCPGYCAWPFHQPIYGPQSPPLVAPNGDVGVDGMIINIATLLVNTVTNPSPEAVSACTGIFGSGAYPGYAGRVLVDKTSGASYNALGLAGRKYLLPALWDPQTSTCKTMV
What is the function of this protein?
May play a role in a brassinosteroid-dependent regulation of growth and development.
What are the official names of this protein?
Protein EXORDIUM-like 4.
What is the protein family that this protein belongs to?
Belongs to the EXORDIUM family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, apoplast.
Protein: RRP15_BOVIN
Sequence: MAAAVGDSRVSAGKKLKISLRKKRMKMVVASVASELEDKDKDASDNEGSLGSCGLEKDHFSSGDEAVEADNEDEAEPREDDNDSAAEATAGANAGWADAMARILSKKIPESKPTILVRNKELEKEKEKLKQERLEKRKQLDKKREWEMMCRVKPDVVKDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGGSIRKRAKLISSVSKKDFISVLRGMDGSASEKNSAGKNSKAKQTEAKSEEGPGWTILRDDFMMGASMKDWDKESDGPDGSRLGCGSDSDT
What are the official names of this protein?
RRP15-like protein, Ribosomal RNA-processing protein 15.
What is the protein family that this protein belongs to?
Belongs to the RRP15 family.
Protein: PG136_MONPV
Sequence: MMPIKSIVTLDQLEDSEYLFRIVSTVLPHLCLDYKVCDQLKTTFVHPFDVFLNNSLGSVTKQDELQATISKLGINYLIDTTSRELKLFNVTLNAGNIDIINHPINISSETNPIINTHSFYDLPPFTQHLLNIRLTDTEYRARFIGGYIKPDGSDSMDVLAEKKYPDLNFDNTYLFNILYKDVINAPIKEFKAKIVNGVLSRQDFDNLIGVRQYITAQDQPRFDITYNIADAARHYGVNLNTLPLPNVDLTTMPTYKHLIMYEQYFVDDYDRVPIYYNGNRVIFNDEIINFTISMRYQSLIPRLVDFFPDIPVNNNIVLHTRDPQNAAVNVTVALPNVQFVDINRNNKFFINFFNLLAKEQRSTAIKVTKSMFWDGIDYEEYKSKTLQDMMFINSTCYVFGLYNHNNTTYCSILSDIISAEKTPIRVCLLPRVVGGKTVTNLISETLKSISSITIREFPRKDKSIMHIGLSETGFMRFFQLLRLMADKPHETAIKEVVMAYVGIKLGDKGSPYYIRKESYQDFIYLLFASMGFKVTTRRSIMGSNNISIISIRPRVTKQYIVTTLMKTSCSKNEAEKLITSAFDLLNFMVSVSDFRDYQSYRQYRNYCPRYFYAGSPEGEETIICDSEPISILDRIDTRGIFSAYTINEMMDTDIFSPENKAFKNNLSRFIESGDITGEDIFCAMPYNILDRIITNAGTCTVSIGDMLDNITTQSDCNMTNEITDMINASLKNTISKDNNMLVSQALDSVANRSKQTIGDLRQSSCKMALLFKNLATSIYTIERIFNAKVCDDVKASMLEKYKAFTDISMSLYKDLIAMENLKAMLYIIRRSGCRIDDAQITTDDLVKSYSLIRPKILSMINYYNEMSRGYFEHMKKNLNMTDGDSVSFDDE
What is the function of this protein?
Core protein 4a is the most abundant virion protein.  Major component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition.
What are the official names of this protein?
Major core protein OPG136 precursor.
What is the protein family that this protein belongs to?
Belongs to the orthopxvirus protein OPG136 family.
Protein: POMT1_DROPS
Sequence: MYNNNNDGGGGGSANGNTMQQRRKTTTRSRSKQQQQQQCTSENVIEKNQTNGAQNERLHFRGSSKDSALSTPLLPRSRSTTSAINSPSPLCCNGGLSILNCCRDVNCHLNAPLRGSVESSRSRRSESRQSSLTATPTTTPKQASPSPTISERSRSCSGSRSRSCSCDGRLVDCHKHSAAAAAASTAAPQFTVNLSIDLFSWTLFLLAFCTRFYKLATPPHIVFDELHYGKYIAHYMRNIFFFDQHPPLGKQLIAGLVSLAGYDGNYTFSRIGAAYAPDVPIFWFRFIPALCGSLLAPAVYRLLLEARLHRWAAALGGLLVVLDNSLLTQSRFVLMESMLLLASTLGIACLLRFQRCRLGSFQWLCNGSAAGVLLACAGAVKYIGFLALALAGYLLCRHLWQLLYDASLTNRQLWMHALSRLLLFVGIPIAVYIGVFYVHFRTLHRAGPHDSIMTSAFQASLEGGLASITSGQPLAVVHGSQITLRHTHGRTCWLHSHAAVYPVRYKDKRGSSHQQQVTCYSFKDVNNWWIVKRPERDDLVVGEQPDVIQHGDVIQLVHGITSRALNSHDVAAPMTPQCQEVSCYIDYEIKMAGELLWRVEILNRNSEGDSWHAIKSEIRLVHESTGAALKFSGRQLPDWGFNQHEVVADRDQVHEDAIWNVEEHRYTKTQDQRERERQLLSAEMIPTKRTKLSFWAKLLELQTKMFWHGKHLQAHMYSSLPHEWPLMDKGIAYWLDSQSSAQIYLLGNVLIWYTASAGILVYATLLAFYAVRRRRLCFDVSQHEWQRFLMAGDTFFVGYMMHYLPYYFVDRTLFLHNYLPAFVFKLLLLCFVVEHLDYLLRRHCSGRGVHLVRVYRLALLLWLLAVGSVFVKFLPLSYGARKMTIEEVRRLRWKDTWDFILQKNYALN
What is the function of this protein?
Rt/POMT1 and tw/POMT2 function as a protein O-mannosyltransferase in association with each other to generate and maintain normal muscle development.
What are the official names of this protein?
Protein O-mannosyltransferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, Protein rotated abdomen.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HIP17_ARATH
Sequence: MGCWLKQPQGITTMMGCWLTKSRENILDNVIVTDAKLKISMNFEDCAKKIRKVACQFEVKSCITDIDDQKVLVSGDFNLHKLVKTLKKKTGKKIEIVTKNEKSSEDKVDDTVQNEDSKDEIVPQNADKPETSIMEVEFDIPFLCEKYEKDFGKVISKCTGVETYVVDLENKKVVVIGNFDKDELSRKLNKKMHQKIKKAEKERQEWESEMMLREAEEEKRLADIYEEIDKDRNVSLNPITDYEKEMAKHYYMFSDENPNACSIS
What is the function of this protein?
Probable heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 17, AtHIP17.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: RLMF_YERPA
Sequence: MLSYAPENAYQRASTMENKKVFPKEKSGLHPRNRHCSRYDFDALSVSCPELIPFLAPTAYGDISVDFADPLAVKMLNKALLKHFYGIEYWDIPADSLCPPIPGRADYVHHLADLLASCNGEVIPKGKNIALLDIGVGANCIYPIIGQREYGWRFTGTDIDSHALSAAKMVVSMNPTLKNTLRLKQQKDPHAIFEGVWAVNERYDATLCNPPFHGSAEEAAATTRRKLHKLGKNEVAAKPVQNFGGKNSELWCEGGEEGFVSRMVAESVAKAQNCFWFTSLISKKTTLPAIYHALRYVKAVEVRTIEMAQGQKVSRFVAWTFLTPEQQAAWVAERWA
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5M_GADMO
Sequence: MHPTTLMYTSSLLLMFAVLLYPLLVTFTSLPLNNDWASSHAKTAVKSAFLISLAPLSLFLSTGMEAVTSSWTWMVTTTLDITLSFKFDHYSIIFIPIALYVTWSILEFATWYMHSDPFMNRFFKYLLTFLVAMLILVSANNLFQLFIGWEGVGIMSFLLIGWWHGRADANTAALQAVLYNRVGDIGLILGMAWLATNVNSWDIQQMFILSKNLDMTLPLLGLILAATGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRMSPLMENNQTALTLCLCLGALTTMFTATCALTQNDIKKIVAFSTSSQLGLMMVTIGLNQPQLAFLHICTHAFFKAMLFLCSGSVIHSLNDEQDIRKMGGLHHLAPFTSSCLTVGSLALTGTPFLAGFFSKDAIIEALNTSHVNAWALTLTLIATSFTAIYSLRVIFFVTMGTPRFLPLSPINENNPAVINPLKRLAWGGIFGGLLVMLNINLFKTPVLTMPAELKLAALAVSILGLLTALELATLTSKQFKVTPLRTPHHFSTSLGFVPAIIHRQIPQLSLLLGQKIASQMVDQTWLEKTGPKAIANATTPLASATSNMQQGLIKTYLTLFLMTLVLVTLISAT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PP103_ARATH
Sequence: MTLQSQSSHCLNVHSSMVRDIEKCEQKTKRDIEKKNTKSGGVRLNSRRLIHGRVAEKGTKSLPSLTQVTFEGEELKLKSGSHYFKSLDDAIDFFDYMVRSRPFYTAVDCNKVIGVFVRMNRPDVAISLYRKMEIRRIPLNIYSFNILIKCFCDCHKLSFSLSTFGKLTKLGFQPDVVTFNTLLHGLCLEDRISEALALFGYMVETGFLEAVALFDQMVEIGLTPVVITFNTLINGLCLEGRVLEAAALVNKMVGKGLHIDVVTYGTIVNGMCKMGDTKSALNLLSKMEETHIKPDVVIYSAIIDRLCKDGHHSDAQYLFSEMLEKGIAPNVFTYNCMIDGFCSFGRWSDAQRLLRDMIEREINPDVLTFNALISASVKEGKLFEAEKLCDEMLHRCIFPDTVTYNSMIYGFCKHNRFDDAKHMFDLMASPDVVTFNTIIDVYCRAKRVDEGMQLLREISRRGLVANTTTYNTLIHGFCEVDNLNAAQDLFQEMISHGVCPDTITCNILLYGFCENEKLEEALELFEVIQMSKIDLDTVAYNIIIHGMCKGSKVDEAWDLFCSLPIHGVEPDVQTYNVMISGFCGKSAISDANVLFHKMKDNGHEPDNSTYNTLIRGCLKAGEIDKSIELISEMRSNGFSGDAFTIKMVADLITDGRLDKSFSDMLS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g64100.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: YL761_MIMIV
Sequence: MNHLNNIINRIFSQDKNKAEKISRYLTTMIDQDYITDDDENILYQFSQEFNNMSDNLFEFIGNVVNQNIVFNVPQLSIYLSEDKIDVPCSRLNTYLKCYWHKITYKSGLLREKVWVPIKDFSGNIIIERANVISYQKEDLPYLLIYISRYLKTIDYRTS
What are the official names of this protein?
Uncharacterized protein L761.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L761/L899 family.
Protein: SBT3H_ARATH
Sequence: MGNSFLIADTSSLVIGLLLILNGVFISAAKHYGLNKIHIVHLGAKQHDTPELVTKSHYQILEPLLGSKEAAKNSLVYNYKHGFSGFAAKLTASQAKNLSAHPEVLRVVPSRVMRLKTTRTFDYLGLLPTSPKSLLHKTKMGSEAIIGVIDSGIWPESQSFNDTGLGPIPKRWKGKCLSGNGFDAKKHCNKKLIGAEYLTVGLMEMTDGIYDYPSLGESMSPRDHVGHGTHVAAIAAGSFVANANYKGLAGGTARGAAPHARIAMYKVCWREVGCITADLLKAIDHSIRDGVDVISISIGTDAPASFDIDQSDIGFGSFHAVMKGIPVVASAGNEGPNAQTVDNVAPWIITVAATSLDRSFPIPITLGNNLTILGEGLNTFPEVGFTNLILSDEMLSRSIEQGKTQGTIVLAFTANDEMIRKANSITNAGCAGIIYAQSVIDPTVCSSVDVPCAVVDYEYGTDILYYMQTTVVPKAKLSPSKTLIGRPIASRVPRFSCRGPNSVSPAILKPDIAAPGVNVLSAVSGVYKFMSGTSMATPAVSGIVGLLRQTHPHWSPAAIRSALVTTAWKTDPSGEPIFSEGSTRKLADPFDYGGGLINPEKVTHPGLIYDMGIDDYLHYLCSAEYDDDSISKLLGKTYNCTSPKPSMLDFNLPSITIPSLTGEVTVTRTVRNVGPARSVYRPVIESPLGIELDVKPKTLVFGSNITKITFSVRVKSSHRVNTDFYFGSLCWTDGVHNVTIPVSVRTKFMRNYV
What are the official names of this protein?
Subtilisin-like protease SBT3.17, Subtilase subfamily 3 member 17, AtSBT3.17.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GRPE_EHRCR
Sequence: MSDNGDNNTKSPQHNNPQPNEKSDGKVQPGQPQVNPQRKFTAGINKKKEKLNEDLSELDKLRQQLIHFQNQFRLAVADKENVKRIMQKNIDDTSIYAISNFARDLLSSCDNLETSLKNLKEGDSIHAGVLMTYKELLNTLERHNITRIDPIGEKFNPQFHKAVSQMVDAEKDDNTILHVVQPGYIIKDKLLRAASVIISKKSD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP9_HUMAN
Sequence: MSSRPGREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE
What is the function of this protein?
Is thought to be a target protein for the PIM1 kinase.  May play some roles in B-cell proliferation in association with PIM1 (By similarity).
What are the official names of this protein?
Retinitis pigmentosa 9 protein, Pim-1-associated protein, PAP-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTU_DROER
Sequence: MSASATRSRNKQSKLRDDERLDISKDEFNRIQEAFGQEEFRKLFFDYVEEIQDPENRKIYEEEITQLEKERGVEVRFIHPKPGFVIKTALDGELKCFINIAGSEEIERPKNEVATDPSSGNRGLSWSIPMAQTSSRDDCDAKNNHCKVFDVVFHPDALHLAKRNKQFRQCLIDTALDAVEREYKVSLDRANLKFPKLDYKGIPRPTVIRKLADNPTAEEQEPHPLAHMFPTQPPAPGKPEPRVLPLKTKPTPVPEFTVPRYSIKHSHDVDLSEYTDELDAKLHVTVPRALVVEIELPLLRSTAECQLDVTSKSVYLFSERQGAKYRLKLDLPFTVDDKAGQARFDTDLRRLSITLPVVRKSSKEQAQMHETLRHFSREDSGVELHSNSESPVEEDPDGELSDSKADISDISSPTAAPVRHSNSPFLKSSVHYQLPSKFDCNVLDNVMAFVLHVPNVQPDSIEQLREQRSLHLQFATIGSGYYPTHYAFYVELPAEHEDSAIESVEAEAWDNNVVLKLCLTSQSETPASYLAGLDATELKEYPVHGQYNVKSKEKVIARKENAPFEIKFEHNQEGQALKVSIRPGTKEEEKENQDQEPEIDQQHQQQVQNKKPGKKQRKRNKKERSLSESACADMILQEPLTKNSELQPKSTFNLPQRKQRSYSECNDSTGGSHRGILKRFSRYGPRPSMSDSCSSIDDCSSYSCSVDASGTSLFSHSFGGIPEEDRSDAGLSESCKKTVRFNDHIMKQVFRLDSSILGQRKKNQKRRDLKLRAQHRRLSEGDSVDYEESRGSALKQQENQSRNCNKPKGVSVLHDSGLDLTGAPGAHSNNNESEAKNAMMFEMDD
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal homolog, PP1-interacting protein 20.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_HELPY
Sequence: MEFLVQKIGMSRTIDANSTPVTLLKVLQAKVCQLENGKALVAYAMHKKHNKAIEGQQKKYQLSKEFNHFATLKASQQKELGDLDLSALETLKRVKASFKTKGRGFAGVMKRWNFQGGPAAHGSRFHRRPGSIGNREWPGRVQKGRKMAGHYGNELVTCQNEVLSFDKESMVLVLKGSVAGFSGAYGRIRAV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y3232_CLOD6
Sequence: MEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIVENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIAEDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNEPKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQKTGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTAILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGISWLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVPPLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD
What are the official names of this protein?
UPF0597 protein CD630_32320.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: RL23_HAHCH
Sequence: MNQERLYKVLLGPHVSEKATLLAEINNQVVFRVAADAKKPEIKKAVEALFDVKVESVQVVNIKGKTKRTARGMGKRNDIRKAYIRLASGQSIDFVDVE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: IPK_HALVD
Sequence: MSLVVLKLGGSVVTDKDEPETVDEAGLAAAADAVAPLAESRRVVVVHGGGSFGHHHAAEHGVSSESGSHDARGVRAIHDAMKRLNDAVLDALEERGVAALPVHPLSAGAREADGSLSLPLAATETMLDEGFVPVLHGDVISHAGKGATIVSGDDLVVSLASGLGADRVGLCSTVPGVLDADGDVIPEITAFADAADALGGSDSTDVTGGMAAKVRKLLALGAPAHVFGPEGLSAFVAGESPGTVIRGE
What is the function of this protein?
Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP).  Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
What are the official names of this protein?
Isopentenyl phosphate kinase, IPK.
What is the protein family that this protein belongs to?
Belongs to the isopentenyl phosphate kinase family.
Protein: APT_STAAU
Sequence: MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_MYCLE
Sequence: MPELPEVEVVRRGLQDYIVGKTITAVRVHHPRAVRRHVAGPTDLTNRLLGTRINGIDRRGKYLWFLLDTDIALVVHLGMSGQMLLGTVPRVDHVRISALFDDGTVLNFTDQRTLGGWLLADLMTVDGSVLPVPVAHLARDPFDPRFDVEAVVKVLRCKHSELKRQLLDQQTVSGIGNIYADEALWRAEVHGARIAATLTRRQLAAVLDAAADVMRDSLAKGGTSFDSLYVNVNGESGYFDRSLDAYGREGEGCRRCGAVMHREKFMNRSSFYCPRCQPRPRR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.