PharMolix/UniProtQA huggingface dataset:
Protein: TRPD_XANCB
Sequence: MPITPQQALQRTIEHREIFHDEMVDLMRQIMRGEVSDAMVSAILTGLRVKKETIGEIAGAATVMREFSRRVEVTDRCHMVDIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSSKSGSADALEALGAVIELQPEQVAASLAQTGIGFMYAPVHHPAMKVVAPVRREMGVRTIFNILGPLTNPACSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVGELRDGQVHEYEVHPEDFGIAMSASRNLKVADAAESRAMLLQVLDNVPGPALDIVALNAGAALYVAGVADSIADGIVRARQVLADGSARACLDAYVAFTQQATAQG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: FTHS_BACAN
Sequence: MTTTTTVKSDIEIAQEANMKKIQEIAADLNILEDELEPYGHYKGKLSLDIFKRLQNEKDGKVVLVTAINPTPAGEGKSTVTVGLGQAFNKIGKKTVIALREPSLGPTMGLKGGAAGGGFSQVVPMEDINLHFTGDIHAITTANNALAAFIDNHIQQGNTLGIDTRKIVWKRCVDLNDRALRNVVIGLGGPVQGVPREDGFDITVASEIMAVFCLATDIQDLKARLSRIVVAYNFANQPVTVKDLGVEGALTLLLKDALKPNLVQTLENTPAIIHGGPFANIAHGCNSVIATTMAAKLGDYVITEAGFGADLGAEKFLDIKARAAGIKPEAVVIVATIRALKMHGGVAKDQLKEENVDALAKGMENLQKHVETIQSFGVPFVIAINKFITDTDAEVAYLQEWCNERGYAVSLTEVWEKGGQGGVDLAEKVLKEIEKGENNYAPLYELELPLEEKIRTIAQKVYGAKDIEFAPKARKQLAQYEGEGWSNLPICMAKTQYSLSDDATKLGRPSDFIVTIRELKPSIGAGFIVALTGTMLTMPGLPKQPAALQMDVNEDGKAVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: NU2M_CANLF
Sequence: MKPPILIIIMATIMTGTMIVMLSSHWLLIWIGFEMNMLAIIPILMKKYNPRAMEASTKYFLTQATASMLLMMGVTINLLYSGQWVISKISNPIASIMMTTALTMKLGLSPFHFWVPEVTQGITLMSGMILLTWQKIAPMSILYQISPSINTNLLMLMALTSVLVGGWGGLNQTQLRKIMAYSSIAHMGWMAAIITYNPTMMVLNLTLYILMTLSTFMLFMLNSSTTTLSLSHMWNKFPLITSMILILMLSLGGLPPLSGFIPKWMIIQELTKNNMIIIPTLMAITALLNLYFYLRLTYSTALTMFPSTNNMKMKWQFEYTKKATLLPPLIITSTMLLPLTPMLSVLD
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YFMQ_BACSU
Sequence: MTWAIVMLILMSLVKIVLTCLPTGVIEWLLGKFEVHAKLSDENASLSLDGKRLEGAEKQKVIDQFNEAIFLEKYYIYPGDEERYLHPENGGTPLVIDTKKGKKDVKLFVYRYDDHIDVVKQYKKKVIAYRVLSESLQKESLSVAGSLA
What are the official names of this protein?
Uncharacterized protein YfmQ.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS4_CHLCV
Sequence: MARYCGPKNRIARRFGANIFGRSRNPLLKKPHPPGQHGMQRKKKSDYGLQLEEKQKLKACYGMILEKQLVKAFKEVINKQGSVTKMFLERFECRLDNMVYRMGFAKTIFAAQQLVSHGHVLVNGKKVDRRSFFLRPGMQVSLKEKSRKLQSVQESLENRDEGSLPSYISVDKGNFKGELLVSPEQDQIEAQLPLPVDVSVVCEFLSHRT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: W_NDVB1
Sequence: MATFTDAEIDELFETSGTVIDNIITAQGKPAETVGRSAIPQGKTKVLSAAWEKHGSIQPPASQDNPDRQDRSDKQPSTPEQTTPHDSPPATSADQPPTQATDEAVDTQLRTGASNSLLLMLDKLSNKSSNAKKGAHGRAPKRGITNVRLNSRGVNPVAETVRKDRRTKSRPPLETRAQT
What are the official names of this protein?
Protein W.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses W protein family.
Protein: Y586_LEGPH
Sequence: MAIISSLANHLLIAMPSLKDPNFERSVVYLCEHNEQGSVGLIINRPLQFPLSIVFEQLQIEPIRVEKNGLPLLFGGPVQPERGFVIHKQMGGWRSSLFLQDEVTVTTSNDIIRAIAYDEGPKDVLITLGYAAWTEQQLEREIMSNTWLVCPYKSEILYEVPFEERWEYAGLTLGIKMNQLSSDAGHA
What are the official names of this protein?
UPF0301 protein lpg0586.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: ATPB_TROWT
Sequence: MTGDAVGRIVRVTGSVVDVEFSRNNLPGVFNALKTRVNRSGKEIEITLEVAQHLGDDLVRTVAMQSTDGLIRGQEVLDTGGHITVPVGDATKGRVFNVVGEVLNSNGEDIKFDEYWSIHRKPPEFSLLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMIQRVAQDHGGVSVFAGVGERTREGNDLIREMQDAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFRDVQKQDVLLFIDNIFRFTQAGSEVSTLLGRIPSAVGYQPNLADEMGVLQERITSTRGHSITSLQAIYVPADDYTDPAPATTFAHLDATTELSREIASKGLYPAVDPLASTSRILDPKYIGKDHYRVAVTVKQILQRDKELREIIAILGIDELSEEDRVTVARARRIEQFLSQNTYMAKKFTGVDGSTVPLQETIDGFDAICRGDCDHIPEQAFFNVGGLEDVERKWSKLQKELG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSAB_ATRBE
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSAISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGESVRWNNFLDVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTAEGAGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLVAGHMYRTNFGIGHSMKDLLDAHIPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAILVIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTSGPAFNAGRSIWLPGWLNAVNENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ERMB_ENTFA
Sequence: MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIPYHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTVTYEQVLSIFNSYLLFNGRK
What is the function of this protein?
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
What are the official names of this protein?
rRNA adenine N-6-methyltransferase, Macrolide-lincosamide-streptogramin B resistance protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: Y4YJ_SINFN
Sequence: MDVAFDLVNYAYASRLRLLKEMQERDARRKLSKKEAQHHMAIVAAQNASRELEIAQQQRAGKEAQLYQELTSLNTLSSAALDHHHLHIERLAAEITIRGQVLDDARIAQEQAETAASETKALWVKRSEARHKWQQIQDDLRRAVDILSEAAGEIEADDEILLRYGRGSLDQRSRNEFR
What are the official names of this protein?
Uncharacterized protein y4yJ.
Protein: RPPH_FRATO
Sequence: MIDKSGYRANVAIVLLNKQNRVFWGQRRNRTSWQFPQGGVATGETPLQAMYRELHEEIGLRPQDVEVIASTRDWYKYDIPDSLVRTKEPICIGQKQKWFLLKLKSPESYIDLDANDSPEFDNWRWVSYWYPINHVVYFKQEVYRKALTYFKEYIA
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PIMT_CITK8
Sequence: MVSRRVHTLLEQLRAQGIKDEQVLDALAAVPREKFIDEAFEHKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEHQFLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_ERYLH
Sequence: MNSYLEFEKPVAQLEARIAELRSAAEGDEVDISNELKRLERKSAALLTSTYSALTPWQKTQVARHPQRPHFRDFVKHAFDEFVPLGGDRNYGEDEAIMGGLATLRGRKVVLIGHEKGNDTESRLRHNFGMGKPEGYRKAIRLMDLAGRFGLPVVTLVDTSGAFPGVEAEERGQAEAIARSTEACLALPVPMVATIVGEGGSGGAVALASAERVLMLEHAVYSVISPEGCASILWRTAEKAPDAAEAMKVTAQHLLDLKVIDRIVKEPTGGAHRDPSAICETLANAIDEELDALADLPGETLRRMREERFLQIGG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKE_VIBPA
Sequence: MSDNLAKAISNPLFPALDSMLRAGRHISTEDLDNHALLSDFELELSSFYQRYNTELVKAPEGFFYLRPRSTSLIGRSVLSELDMLVGKVLCFLYLSPERLAHEGIFTNQELYDELLALADEKKLMKLVTNRATGSDLDKEKLFEKVRTSLRRLRRLGMIINIGETGKFSISEAVFRFGADVRVGDDIREAQLRLIRDGEAVVHTKEPSQGSLLSEEDQEEQAQEEMTEEGEA
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Probably acts via its interaction with MukB and MukF.
What are the official names of this protein?
Chromosome partition protein MukE.
What is the protein family that this protein belongs to?
Belongs to the MukE family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: HSP1_PLEAU
Sequence: MARYRCCRSQSRSRCRRRRRRCYRRRRRCCRRRRRRVCCRRYTVVRCRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HIS4_CLOD6
Sequence: MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGAEYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVILGSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGVQTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAIIGKALYDKKIDFKEAQQLCLLGE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBB_XYLFA
Sequence: MNALQWSFRAQCLTGFLFCTGLLAYAIFLQLHQGLEPCPLCIFQRIAFAVLGILFLIAGLYNSSNVYTRKAYGLLIFLTAAIGTGIAGRHVWVQLMPHNTISSCGSPLSFLSETMGPFEVFRTVLTGTSDCGNIDWRFLGLSMPMWSMFWFVALALLGLLVGFKAERRKPLFS
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBFA_SALEP
Sequence: MAKEFGRPQRVAQEMQKEIAIILQREIKDPRLGMMTTVSGVEMSRDLAYAKVFVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTNVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBX6_BOVIN
Sequence: MYHPRELYPSLGTGYRLGPPQPGADSSFPPALAEGYRYPDLDTPKLDCFLSGIEAAPRTLAAPPPLPPLPPALGTEPSPPSAPEGLHSLPGVSLSLENRELWKEFNSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVVPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGVASFRFPETTFISVTAYQNPRITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATAGYGSGDAPGGPCDSTLGGDVRESDPEQAPVPGLPLPQLLPAVAPVLRPTCCTLPLSTGPPVTFQPGIPASRRLQTLPSALLSRLPGAAARASRLRIPSSSTLSILCLALPPRGPLPTALPWAWGLPRCGLQTNVLSLCSLPPGLLPPHFHYPFPHTK
What is the function of this protein?
T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal.  Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development.  Seems to also play an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).
What are the official names of this protein?
T-box transcription factor TBX6, T-box protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRMA_STACT
Sequence: MNWMEVSIVINHEVQEFVTSILEENESNGVVIEDSKDLDGELADKFGEIYELDPNDYPDTGVRVKAYFNEIDYSEELKNQLLRNIQELAELDKNIFDYNEQIIKESDWENEWKNYFHPFKASKNFTIVPSWETYQKESDSELCIELDPGMAFGTGDHPTTSMCLNAIEQYVKPSDSVIDVGTGSGILSIACHLLGVRHIKAVDLDELAVRVAKENFEKNSCENAIETTTGNLLKGETNKYDVVIANILAHIIEEMIEDAYNTLNEEGRFITSGIIIEKSDEIIEHMKRVGFNIISINHDNGWACIVGEKVSN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_SACHY
Sequence: MALTVMASSATAAAPFQGLKSTASLPVARRSTTSLAKVSNGGRIRCMQVWPAYGNKKFETLSYLPPLTQEQLLKQVDYLLRNNWVPCLEFSKEGFVYRENSTSPCYYDGRYWTMWKLPMFGCTDASQVYKELQEAIASYPELRAILGFDNIRQTQWLTFIAYKPAGSE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LRC40_CHICK
Sequence: MAAARRARAGDPRAGFRRAAEEQSPAVPQGLIRAARKSGQLNLAGRGLGEVPQHVWRINLDTPEEAHQNLSFGAADRWWEQTDLTKLILASNQLRCLSEDVRLLPALTVLDVHDNQLTSLPSALGQLENLQKLDVSHNKLKSIPEELLQLSHLKGLLLQHNELSHLPDGFGQLVSLEELDLSNNHLTDIPKSFALLINLVRLNLACNQLKDLPADISAMKSLRQLDCTKNYLESVPSELASMASLEQLYLRKNKLRSLPELPSCKLLKELHAGENQIEILNAENLKHLNSLSVLELRDNKIKSVPDEITLLQKLERLDLANNDISRLPYTLGNLSQLKFLALEGNPLRTIRRDLLQKGTQELLKYLRSRIQDDKASPNEEPPVTAMTLPSESRINMHAITTLKLLDYSEKQVAVIPDDVFSAVRSNPVTSVNFSKNQLTAIPPRIVELKDSVCDVNFGFNKISSVSLELCTLHKLTHLDIRNNVLTSLPEEMEALTRLQVINLSFNRFKVFPSVLYRMLALETILLSNNQVGSIDPLQLKKMEQLGTLDLQNNDLLQVPPELGNCETLRTLLLEGNPFRTPRAAILAKGTAAVLEYLRSRIPT
What are the official names of this protein?
Leucine-rich repeat-containing protein 40.
Protein: SYR_AGRVS
Sequence: MNLFADFENRIKTALETLDLVKEKRSELSFDRIVVEPPRDASHGDAATNAAMVLAKPLGVSPRVLADLIGEKLKEDADIAEVSVAGPGFLNIRLSVAYWQRLLANVIAGGTDFGRSQTGAGRKVNVEYVSANPTGPMHVGHCRGAVVGDALANLLAFAGYGVTKEYYINDAGSQIDVLARSVFLRYREALGEAVGEIPAGLYPGDYLIPVGEALAQEYGVRLHNMPEEQWMEIVKDRAIDAMMVMIREDLAALNVHHDLFYSERQLHANGAAAIRTAINDLTFKGHVYRGTLPPPKGQLPEDWEDREQTLFRSTEVGDDIDRPLIKSDGSYTYFAADVAYFKDKYDRGFDRMIYVLGADHGGYVKRLEAVAKAVSEGKAKLTVLLCQLVKLYRDGEPVKMSKRSGDFVTLRDVVEEVGRDSVRFMMLYRKSSEPLDFDFAKVTEQSKDNPVFYVQYAHARCMSIFRQAREAFGDIDLSPDVLEAAVTGITEPSEVQLIAKLAEYPRIIEASAQSMEPHRIAFYLYDLASSFHAHWNKGKDQPELRFVNDKNRQSSLARLGLVHAVASVLQSGLAITGTDAPQEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO5_SULIK
Sequence: MRGSSNRKIDPRIHYLVPKHEVLSIDEAYKILKELGIRPEQLPWIRASDPVARSINAKPGDIIRIIRKSQLYGEVVSYRYVISG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB1_XANAC
Sequence: MTLETPVRVLIVDDSAVVRQMLTEILSRDAGIEVVGSAADPLLAREKIKRLNPDVITLDVEMPRMDGLVFLENLMRLRPTPVVMISSLTERGADTTLQALSLGAVDFVSKPKIDVARGLEGYAEEIVSKVKMAAKAKVSALNRPSAPKVTLDMQSAPVAGSALRFRTTDRLIAIGASAGGTEALRVVLEHMPADAPAVVMTQHLPASFSTAFAERLNRHSAMSVREATDGEAILPGHAYLPPGGQHLRIIRDGARWRCRIDDGPPVNRHKPAVDVLFRSVAANAGPNAVGAILTGMGDDGARGLLEMLQAGAPTLVQDEASSVVWGMPGAAYKLGAAQEVVPLDRVAERLLALSAQAR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_CLONN
Sequence: MSNITGLTNKIIEDAKVSSKEIMDDAKKKEKIIIDEKVSIAENERKLILSKAEEESKVRAGRIISNANLQVRDMKLSAKIEVLDNVFNAAVEELSRMTGGELLNFIKNTILLLDIDGDEEIIVGENEDRVTTEFINEINKELNAKGKLGKIKLSQKRIKIKGGYILAKNGIEINNTFESRVKSLRDDMEAEVAKVLFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: ERR2_MOUSE
Sequence: MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGIALSTHANGLDSPPMFAGAGLGGNPCRKSYEDCTSGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYNCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSENSPYLNLPISPPAKKPLTKIVSNLLGVEQDKLYAMPPNDIPEGDIKALTTLCELADRELVFLINWAKHIPGFPSLTLGDQMSLLQSAWMEILILGIVYRSLPYDDKLAYAEDYIMDEEHSRLVGLLDLYRAILQLVRRYKKLKVEKEEFMILKALALANSDSMYIENLEAVQKLQDLLHEALQDYELSQRHEEPRRAGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
What is the function of this protein?
Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcriptional activity (PubMed:27601327, PubMed:23169531, PubMed:23508100, PubMed:26206133, PubMed:20534447, PubMed:18662995, PubMed:18957414, PubMed:27723719, PubMed:23019124).  Plays a role, in a LIF-independent manner, in maintainance of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways (PubMed:18957414, PubMed:26206133, PubMed:20534447, PubMed:23040478, PubMed:23040477, PubMed:23019124, PubMed:23169531).  Upon FGF signaling pathway activation, interacts with KDM1A by directly binding to enhancer site of ELF5 and EOMES and activating their transcription leading to self-renewal of trophoblast stem cells (PubMed:26206133).  Also regulates expression of multiple rod-specific genes and is required for survival of this cell type (PubMed:20534447).  Plays a role as transcription factor activator of GATA6, NR0B1, POU5F1 and PERM1 (PubMed:18662995, PubMed:23508100, PubMed:18957414).  Plays a role as transcription factor repressor of NFE2L2 transcriptional activity and ESR1 transcriptional activity (By similarity).  During mitosis remains bound to a subset of interphase target genes, including pluripotency regulators, through the canonical ESRRB recognition (ERRE) sequence, leading to their transcriptional activation in early G1 phase (PubMed:27723719).  Can coassemble on structured DNA elements with other transcription factors like SOX2, POU5F1, KDM1A and NCOA3 to trigger ESRRB-dependent gene activation (PubMed:23019124, PubMed:23169531, PubMed:18662995, PubMed:26206133).  This mechanism, in the case of SOX2 corecruitment prevents the embryonic stem cells (ESCs) to epiblast stem cells (EpiSC) transition through positive regulation of NR0B1 that inhibits the EpiSC transcriptional program (PubMed:23169531).  Also plays a role inner ear development by controlling expression of ion channels and transporters and in early placentation (PubMed:9285590, PubMed:17765677).
What are the official names of this protein?
Steroid hormone receptor ERR2, Estrogen receptor-like 2, Estrogen-related receptor beta, ERR-beta, Nuclear receptor subfamily 3 group B member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome.
Protein: RL36_RUEST
Sequence: MKVKNSLRSLKNRHRDCRVVRRKGRVYVINKTQRKFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.