PharMolix/UniProtQA huggingface dataset:
Protein: GCSPA_FRATM
Sequence: MSFIPHKLEQIKKMLDTIGASSVDQLFDEIPRHLRADTLKIKDGINEIQLANLMRKRANKNHHNINYIGAGAYSHHIPAAIWDIVARGEFYTAYTPYQAEASQGGLQVIYEFQTMMAGLTGMDASNASMYDGATALAESVLMAIRSNKKAKSQKVLIAEALHPTYLRVLETITKHQGIEFDIVNLDSKNGKTDVTKLEDFANTNYAAVVIQSPNFLGQLADVDGITNWAHKHGALVVAVTNPMSLAILKSPAEWGDNGADIVCGEGQPMGVPLASGGPYFGFMTCKMAHVRQMPGRIVGRTVDLDGNEGFCLTLQAREQHIRRAKATSNICTNQGLMVTAATIYMSLLGAEGLERVASISHENTQTLATELAKINGVSIRFNSAFFNEVVIDLPVNAETFVTEMEKEAIDAGYFLGEYHSDLANSIMVCATEIHTSEDIKEYIEATKKVLARIGG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: AMML_ASTMO
Sequence: ESGINLQGDATLANN
What is the function of this protein?
Lectin that binds strongly to galactose, lactose, D-raffinose, L-rhamnose and cellobiose, and less strongly to D-glucose, D-xylose and L-arabinose.  Does not bind D-galacturonic acid, D-fructose, D-mannose, D-ribose, L-sorbose, maltose and sucrose.  Has hemagglutinating activity towards human type O and rabbit erythrocytes.  Has strong antifungal activity against B. cinera with an IC(50) value of 1. 2 uM, and weaker antifungal activity against D. turcia, F. oxysporum and Colletorichum sp.  Lacks antifungal activity against F. oxysporum and M. arachidicola.
What are the official names of this protein?
Antifungal lectin AMML.
Protein: WZC_SALTI
Sequence: MTEKVKQSAAVTGSDEIDIGRLVGTVIEARWWVLGTTAIFALCAVIYTFFATPIYSADALVQIEQNAGNSLVQDINSALANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVTKNTFPLFGAGWERLMGRHNEMVKVTTFTRPETMSGQIFTLKVLGDKRYQLVSDGGFSAQGVVGQPLNKDGVTMRVEAIDARPDTEFTVSKFSTLGMINNLQNNLTVTETGKDTGVLNLTFTGEDRDQIRDILNSITRNYLQQDIAWKSEEAGKSLAFLAKQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLFTKAHPAYRTLLEKRKGLEDKKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITEASTVGNVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNRGIESPQALEEHGISVYASIPLSEWQKARDSVKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMLTGVSSSIGKTFVCANLAAVISQTHKRVLLIDCDMRKGYTHELLGTNNVDGLSDILAGKGEIASCAKPTAIANFDLIPRGQVPPNPSELLMSERFGELIAWASSRYDLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFDQNGIQVKGVILNSIFRRATGYQDYGYYEYEYQSDSK
What is the function of this protein?
Required for the extracellular polysaccharide colanic acid synthesis.  The autophosphorylated form is inactive.  Probably involved in the export of colanic acid from the cell to medium (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase wzc.
What is the protein family that this protein belongs to?
Belongs to the etk/wzc family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATC_THEAC
Sequence: MDSTYIGSYGRLRVYQTEFFSRQQIDQMLSMTDPKDVSAFLYNGPYREDYDSLSAVFKDPDLTEMAINRHMVRNNRLVLFAIPPLAKNAVVAYLSKWDIENIKTVISAKFLGHGIREAEPFLVSFRDIPLGIMSGTLTNEDYRNMINLPNIEAILNYLARFGYGTYMMQFLEDYRKTGDISPMLYSLDRYYYMNLLSALKYYRGDEAPVLNYVRSDIDRQNIVTMLKGKVLKIPFERMSSGIIDGGNIGVNRLREIYSSQDAVSVADALKQYYDLEEPKKKYMETGDLYHFDIAIRNIIARRFLDTMSMLPLSLDSLFYFILRSEIERHNLRTIYLSKVNGMPREITESLLITEMM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: Y482_TREPA
Sequence: MFERNVPSVLLRNIGVSAADPQARFSVAARVRNASNDAHGFGEPISFLLDVAAGAQDASLRGVVDLRRAHPDLVDVSCTARGIPLAVPAPAEGFPELSGVLGLHTQVFVRKDHSVELKMGARISDSVLRAAPFEPRVLFDVYADVLRQIRQIAFEATVRVSAEGALSISVESDADGAFVRALSRAFAQQVDALRRAVIAEGERFLAQQRRVYAQEIAQVTQLVSRAEDAIAQLGVSSRVIQQKRAEAERLLEAAARKALGEVTKRAADELQNKARDAFRSFF
What are the official names of this protein?
Uncharacterized protein TP_0482.
Protein: PROQ_EDWI9
Sequence: MENQPKLNSSKEVIAFLAQRFPQCFSTEGEARPLKIGIFQDLVARMQGEENGLSKTQLRSALRLYTSSWRYLHGVKLGAERVDLDGNACGVLDEQHVEHARQQLEEAKARVQAQRDARKREAAENGEKREPRRPRPAGKKPTARRDGEQGSKEVRKPRAAKATSERKPRAKSETTEQRSTPVTSLEQLHLGQTVKVSAGKHAMEASVLEITKDGVRVQLSNGLAMIVRTEHLQF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZFP62_HUMAN
Sequence: MSHLKTSTEDEEPTEEYENVGNAASKWPKVEDPMPESKVGDTCVWDSKVENQQKKPVENRMKEDKSSIREAISKAKSTANIKTEQEGEASEKSLHLSPQHITHQTMPIGQRGSEQGKRVENINGTSYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVHKRIHTGEKPYKCEECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKRIHTGERPYECDVCGKAYISHSSLINHKSTHPGRTPHTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDRCGKAFRNSSGLTVHKRIHTGEKPYECDECGKAYISHSSLINHKSVHQGKQPYNCECGKSFNYRSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTHTGEESLNVIYVGSYSGTSQKRTYEGGNALDGGRMRMPL
What is the function of this protein?
May play a role in differentiating skeletal muscle.
What are the official names of this protein?
Zinc finger protein 62 homolog, Zfp-62.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BGM_DROME
Sequence: MSTIDALYNRPGPNRLRQADAYRTTNRQDAVKIRMAKDGIGAEEPISVPGLLKRTVNNYGDYPALRTKNGKNGYHTVTYKQYEQKVHQVAKAFIKLGLEEHHSVGVLAFNCAEWFYSAMGAIHARGIIAGIYTTNSADAVQHVLESSHAQIVVVDDAKQMDKIHAIRDKLPKLKAAIQIQEPYSPYLKKEDGYYRWSEIESMNVSDVEDQYMTRLENVAINECCCLVYTSGTVGMPKGVMLSHDNITFDVRGIVKAMDRVVVGAESIVSYLPLSHVAAQTVDIYTCAFVAGCIWFADKDALKGTLVKSLQDARPTRFMGVPRVYEKFQERMVAVASSSGSLKKMLASWAKGITLKHYMVSQGKSSGGFRYKIAKSLIMSKVKQALGFDRVLTLASAAAPMSPETKKYFLSLDLKIVDAFGMSETAGCHTICLPDSVGLNTIGKTLPGCESKFINKDANGHGELCIRGRHVFMGYIDNKEKTEESLDDDCWLHSGDLGFVDDKGYVSLTGRSKEIIITAGGENIPPVHIENTIKKELDAISNAFLVGEQRKYLTVLITLKTEVDKDSGEPLDELSHESSVWVKSLGVEHKTVSDILAAGPCPKVWKSIEDAIKRANKQSISNAQKVQKFTILPHDFSIPTGELGPTLKVKRNVVSKMYADEIEKLYA
What is the function of this protein?
Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:10373116, PubMed:26893370, PubMed:29739804).  Probably by regulating lipid storage and catabolism, plays a role in neuronal function (PubMed:25409104).
What are the official names of this protein?
Very long-chain-fatty-acid--CoA ligase bubblegum.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily.
Protein: HSP1_NASLA
Sequence: MAKSRCCGSQSRSRCCRPRQRCRRRRRRSCRARRRAMRCCRRRYRLRCRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CCME_STRM5
Sequence: MTPVQRRRLVWVLLALLASGLATALVAMALERNIAYLYTPSEVLRGDVDAQSRFRLGGMVVKGSFNRPVGSLEARFEVTDGDAQLAVTTSRILPDMFAEGTAVVASGRLQDGIFVADEVLAKHDEKYVPKEVADKMGDAHRKHDVPVTAPEVR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: TRPD_XYLFM
Sequence: MSMTAQKALQRIIEHREILQDEMVQLMRQIMNGEVSGIMVAAILAGLRVKKETVGEIAGAATVMREFSRKVNVQDRTHLVDIVGTGGDGWHTFNISTCAMFVAAAAGAKVAKHGNRSVSSKSGSADVLEVLGASIELQPLEVAEAIGCIGVGFMFAPIHHPVMQVVSPVRREMGVRTIFNILGPLTNPADAPNILMGVFDPDLVCIQAHVLHKLGAERALVVCGRDGMDELSLGTTTLVGELRGGRVREYEVSPEDYGMAVSPISNLQVESPAESREMLLNVLAGKPGPALDVVALNAGAALYVAGVAQDIGHGVVLASEVLFDGRARDILDQYVAFTRRAHYV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: MSCA_EMENI
Sequence: MTTPVNEVPEPSYPAAERRRRSDSDSSPTVDGNAYVHDESQPHDGAYAGAQYGSHLQVDTTFQDFDKTSRSPSAAREQAMRLEDDLAVLEAERVASRSTHGTEKDARSGDVHSLTRSRSRRAEDVDEFDEATNPLHEKAAVYNPPENPSTGVSKFIKRVHESSFIVRYFTYIVPLVLILLIPLLVGALAYPDASVGGVELLWFSVWLEIVWLTLWAGRIVAKLLPTPVNIFASIFTNNSKKWRDVAKQLELPVTLFLWWLGVEISFLPTMKNHHVDGNSRTRDWENTLNKIIISVFVWTILNLIEKFLLQLIAMSFHRRTYSDRIEINKFQIGSLTKLYAFSRNKIAETDEAFEEKQDKSGSGAKTPLRYAGKARGLALGALNKVGDVAGAVAADFTGRKANSSSHPSQVVIALLRTTAGCQTLARRLYRTFVREGFDTVFPGDLKEAFDDNEEAEAAFSMFDKDMNGDISMEELEAVCVEIGRERKAITASLKDLDSVVSRLGNVFEFFVAVIAIIVFLTLISTSAAGVLTSAGSSILALSWLFSATAQEFLQSVVFVFVKHPFDVGDRVTIYGNSGEAGLGDDYYVKQISLLYTEFKKMQGHIVQAPNSYLNTLFVLNQRRSGALAEAVPVVIKYGTTLEQMDALRQRLLEFVRSERREFQTNILTELRAVTENFSVTLNVVFFYKSNWQNEGLRLQRRNKFICMLMVALQEIGIEGPRMNLQGASVDIPYHIAGFPPPYQARDGPPVNDDGGQHPPHTPSSGDDQHHQPGHSPSYRRPSILRKGMVAANARARGVSISSRKHVDFSLGMRDVASNDIMGDVFEARSPAADSAVRQVIAERRIQEEEAERQSVESSRQRNSGSRTNLTVPTSTNEARHSIDSQGASSLSSISRNRFFRHRSHSHSTRQEDLMEQGRSSEQGSSSAAAIRPISPSYHPDEKKL
What is the function of this protein?
Acts as a mechanosensitive calcium channel in response to membrane stretch (By similarity).  Regulates intracellular calcium levels and cell volume for survival in response to hypo-osmotic shock (By similarity).  Involved in maintaining vacuole integrity and protecting the nuclear envelope upon hypo-osmotic shock (By similarity).
What are the official names of this protein?
Mechanosensitive ion channel protein A.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
Protein: RL18A_HALMD
Sequence: MSEFTVTGTFESRDGNQPFEKTVEAPNENVARDRAFAAFGSEHGLKRTQVEISEVAQ
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: DNM1L_CAEEL
Sequence: MENLIPVVNKLQDVFATLGRKEDQIQLPQIVVVGSQSAGKSSVLENLVGRDFLPRGTGIVTRRPLILQLNHVALDDESKRRRSNGTLLTDDWAMFEHTGSKVFTDFDAVRKEIEDETDRVTGVNKGISLLPISLKIYSHRVVSLSLVDLPGITKIPVGDQPVNIEEQIREMILLYISNPSSIILAVTPANQDFATSEPIKLAREVDAGGQRTLAVLTKLDLMDQGTDAMDVLMGKVIPVKLGIIGVVNRSQQNILDNKLIVDAVKDEQSFMQKKYPTLASRNGTPYLAKRLNMLLMHHIRNCLPALKARVSIMNAQCQSDLVAFGEPVEDKNRTLLQIITRFATAYTSTIEGTARNIETTELCGGARICYIFHDTFGRSLESVNPLENLTQLDILTAIRNATGPRPALFVPEVSFELLVKRQIQRLEEPSLRCVELVHEEMQRMVQHCGFTTQQEMIRFPRLYDKINEVVSGVLKERLKPTNELVENLVAIELAYINTKHPEFTEANLVTLLKEELLLDDRHGRSRNRHASTGERAVSAHGEQQLQPVPGVNGVDLNAVLQQQQQQSQNQRASNGFLGLFGNAAASSKTSPQEKQSANFLPEVPETQLGRKLTSREQRDVAIIERLIRNYFIIVRKNIQDSVPKAIMALLVNFVRDNLQSELVRQLYKPDEMDDLLAETEDMAQRRRDTLETMKALQQASVIISEVRETQVW
What is the function of this protein?
Functions in mitochondrial division (PubMed:18722182, PubMed:10619028, PubMed:15716954, PubMed:19327994).  Functions in peroxisomal division (By similarity).  Mediates membrane fission, perhaps mainly of the mitochondrial outer membrane (PubMed:10619028).  Mitochondrial fission may be promoted by recruitment to mitochondrial membranes via the egl-1/ced-9 complex (PubMed:21949250).  Involved in the coordination of mitochondrial division with autophagy in response to acute heat stress during larval development (PubMed:33734301).  Plays a role in apoptosis by promoting mitochondrial elimination and cell-death execution, acting downstream of caspase ced-3, and perhaps independently of FIS1-related protein fis-2, caspase ced-9 and apoptosis-inducing factor AIFM/wah-1 (PubMed:15716954, PubMed:18722182).  Role in promoting apoptosis dependent upon cleavage of drp-1 by ced-3 (PubMed:18722182).  Involved in negatively modulating longevity in concert with the Insulin/IGF-1-like signaling (IIS) mediated pathway (PubMed:21463460).
What are the official names of this protein?
Dynamin-1-like protein drp-1, Dynamin-related protein drp-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Protein: LFTR_HERAR
Sequence: MIPWLEADDPFPNVSSALTEADGAPGLLAAGADLSAERLLLAYQNGIFPWFSEGQPILWWSTDPRMVLFIQDFKISASLKKTLKKIDRSMIANGRWQIRFDHAFEDVMRACAAPRNGEAGTWISDDIIAGYTRLHRLGYAHSSELWLDDELVGGLYGVSIGNMFYGESMFTRVTDASKIALAYLVRFLGSHGVSMIDCQQQTAHLASLGAMPISRTEFISLLRQAIAAPQIMDWKPIPMFEVN
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETG_MICAN
Sequence: MIEPLVLGIVLGLIPITLAGLFVAAYLQYKRGNQFGLD
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: TO1B_HADFO
Sequence: SPTCIRSGQPCPYNENCCSQSCTFKTNENGNTVKRCD
What is the function of this protein?
Inhibits insect, but not mammalian, voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-hexatoxin-Hf1a, Omega-HXTX-Hf1a, Omega-atracotoxin-Hf1a, Omega-AcTx-Hf1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 08 (Shiva) family. 01 (omega toxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DHAM_KLEOK
Sequence: MVNLVIVSHSARLGEGVGELARQMLMNDGCKLAIAAGIDDPASPIGTDPIKVMEAIESVADADHILVMMDIGSALLSAETALDLLDPAIAAKVRLCAAPLVEGTLAATVSAAAGAGIDKVIEDAMNALEAKRVQLGLPSQPQHASLTAAPVDDRDARSVSVVIQNHNGLHVRPASKLVAALAGFNADLVLEKGGKCVTPDSLNQIALLQVRRNDTLRLLARGPDADAALAAFQALAAENFGEPTEAAPARRPASADRVEGKVVLYPQPQDRISRETSAAIGQQQLRLKRAIDRTLEDLSALTTLAEATFSADIAAIFSGHHTLLDDPDLYAAACDIIRDEQCSAAWAWQQVLSDLSQQYRHLDDAYLQARYIDIEDILHRTLRHLNERNEALPQFSAPSILVADDIFPSTVLQLNAEQVKGICLQAGSELSHGAIIARQAGIAMLCQQSDALTLQDGENVILDIPGKRVIRG
What is the function of this protein?
Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone.  DhaM serves as the phosphoryl donor.  Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
What are the official names of this protein?
PEP-dependent dihydroxyacetone kinase, phosphoryl donor subunit DhaM, Dihydroxyacetone kinase subunit M.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: SRSF9_HUMAN
Sequence: MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY
What is the function of this protein?
Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.  Represses the splicing of MAPT/Tau exon 10.
What are the official names of this protein?
Serine/arginine-rich splicing factor 9, Pre-mRNA-splicing factor SRp30C, Splicing factor, arginine/serine-rich 9.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Note=Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post- transcriptional regulation of mRNAs in stressed cells.
Protein: GLE1_CHATD
Sequence: MAGSSPLNHHLWSSPSRTVEEILAEDRNSEARHRYLLELARKEHERVREEAARIYREQLAREERERLLAERRKEEERIRLEQQIAAENARLNALKATRIEIPPLLPDPVPAPSTVNGKPTLPAAVATEAKRCPSEPSLVNGIASNGVVEAPAAASIKTLEPAKPAASAFKAAGSATTAAPVAPIASVQPSTNGVVSAVASTPKTAPPAPTETPPDRYVEIHRNLKGLRKYMAEQAKTNLKLKQRMGDMRREIRKSVGQLTTGGMAANKDKQQKIKSILTEALSNQVESALVDPNNFVVEPRKPVEGATNNDPLLPSIFVYLINIFAKAAISQFINEAGARPETADPVGICVAAILSEPDFLWRGASLIDILIAKFRIVCPVLFGYRGSEKTEQGRQRLGWWKESGQWISEQQHMDRMTGLGAGFAAISLRKFALSKKQNPYPPRFYWMAMAKIVNTPPAEISNTQCVVLKAMVQNYEAKFIEFYGSAAIAALRTALIDFPARAPHKSAAVNSLEVLAQMLKRDTGLDLG
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.
What are the official names of this protein?
mRNA export factor GLE1, Nuclear pore protein GLE1, Nucleoporin GLE1, RNA export factor GLE1.
What is the protein family that this protein belongs to?
Belongs to the GLE1 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Biased towards cytoplasmic side.
Protein: NRDR_PETMO
Sequence: MKCPFCGYEETKVLDSRPVSNGTSIRRRRECLQCQARFTTYERYEQTRIRIIKKDGRRELYDRKKLMNGILKACEKRPVSTDQIEEIVDNIEEQLRRSGNSEIYSSEIGDKVMEQLKSIDQVAYVRFASVYKEFRDLDSFLQAIRELKNS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL3_TRIV2
Sequence: MSVGILGTKLGMTQIFDEAGVAIPVTVVQVGPCVVTQVKSKQTDGYAAIQVGYGEVKPKALNRPLLGHLAKSSAPALRHLKEYHTDSSSDYALGQEIKADIFSAGELVDVIGTSIGRGFAGNQKRNNFGRGPMSHGSKNHRAPGSIGAGTTPGRVYPGKRMAGRLGGTRVTIRKLTVIRVDAERNLLLIKGAVPGKPGSLLSIVPAKKVGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NFX1_MOUSE
Sequence: MAEAPPVSGTFKFNTDAAEFIPQERKTSGLNCGTQRRLDSSRIGRRNYSSSPPCHLPRHIPYEDISAVHQHSYASGSKPKSPQGFFQSSNKSLKNHGLQNQPWQKARNEKHQNRNKKAQGLSEQTSDTSSLESVARSESGTNPREHSPSESEKEVVIADPRGAKPKKAAQLTYNYGRGPKAKGRLRSEWGNRMSPKSEDENTRPVAISHTDSSDASCRKPVVDPCVCRRNEQRRYPQKRPPWEVEGARPRPGRNPPKQESQRHINAGPKTNMSPIPKDNLRERPTKSACDTGNLAVVSKSSRRVNQEKTAVRRQDPQVLSPFPRGKQNHMLKNVETHTGSLIEQLTTEKYECMVCCELVQVTAPVWSCQSCFHVFHLNCIKKWARSPASHADGQSGWRCPACQNVSAHVPNTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCPPCPAFTTKTCECGRTRHTVRCGQPVSVHCSNACENILNCGQHHCAELCHGGQCQPCRIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGSHTCSQVCHPQPCQPCPRLPHLVRYCPCGQTPLSQLLEHGSNARKTCMDPVPSCGKVCGKPLACGSSDFIHTCEKLCHEGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVDKEHKCPLICGRKLRCGLHRCEEPCHRGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARIHECDHPVYHSCHSEEKCPPCTFLTQKWCMGKHELRSNIPCHLVDISCGLPCSAMLPCGMHKCQRLCHKGECLVDEACKQPCTTPRGDCGHPCMAPCHPSLPCPVTACKAKVELQCECGRRKEMVICSEASGTYQRIVAISMASKITDMQLGDSVEISKLITKKEVQQARLQCDEECAALERRKRLAEAFDITDDSDPFNVRSSASKFSDSLKDDARKDLKFVSDVEKEMETLVEAVNKGKNNKKSHCFPPMNRDHRRIIHDLAQVYGLESISYDSEPKRNVVVTAVRGKSVCPPTTLTSVIERETQTRPPPPIPHHRHQADKAPGSSTLQKIVKEAVIDYFDVQD
What is the function of this protein?
Binds to the X-box motif of MHC class II genes and represses their expression.  May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma.  Together with PABPC1 or PABPC4, acts as a coactivator for TERT expression.  Mediates E2-dependent ubiquitination.
What are the official names of this protein?
Transcriptional repressor NF-X1, m-Nfx.1, Nuclear transcription factor, X box-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the NFX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAD_RHOPS
Sequence: MTSEQTLLVLGIETTCDETAAAVVERRADGSGRILSNIVRSQIDEHAPFGGVVPEIAARAHVDLLDGIVANAMREAGTGFAQLSGVAAAAGPGLIGGVIVGLTTAKAIALVHNTPLIAVNHLEAHALTPRLTDATEFPYCLFLASGGHTQIVAVLGVGDYVRLGTTVDDAIGEAFDKIAKMLGLPYPGGPQVERAAASGDAARFAFPRPMLGRPDANFSLSGLKTAVRNEASRLTPLEPQDINDLCAGFQAAVLDSMADRLGAGLRLFRERFGAPKALVAAGGVAANQAIRRSLREVAAKAQTTLMVPPPALCTDNGAMIAWAGAERLALGLTDTMDAAPRARWLLDANATAPGKFANTRAGF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_DESPS
Sequence: MNDTVEKSIERAKVLIESLPYMQEFRHKTIVIKYGGHAMVDEALKKQFALDVILLKQIGINPIIVHGGGPQINNLLDRLDIKPSYVQGMRVTDGETMDVVEMVLVGKVNKEIVGLINHCGGKAVGLSGRDGDLVCAEQLQMNQAQVGDNPPELIDVGRVGQVTKINSHVLETLSQDDFIPIIAPVGVGEDGRAFNINADLVASAIAAELSAEKLILLTDVPGVKNKAGDLLTTLEWQELNGLIEDGTIMGGMIPKVRCCEDAVKGGVAKTYIVDGRVEHAILLEIFTRDGVGTEIY
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.