PharMolix/UniProtQA huggingface dataset:
Protein: SYR_CHLAD
Sequence: MRYALERFITDIKDAIAATGKVPVDLIEITTPKPNIPADRTFVTFKAAKVLGVDPAKLAAELAATIAPPPDSLIGEVTATGAFLNFSLHPQRLAAAVLNEIETAGEAYGTVADGAGRTVVIDYSSPNIAKRMHVGHIRSTIIGQALVHIFRALGYRVIGDNHLGDWGTQFGIILAAMQRYGRPQNEGEAAMAELEALYARYNAEMKDDPALEDEARRWSLALERGDPEARSLWQWCVDLSLRAAQRNYDRLGIRFDYAYGESFYEAMLPGVIEEALRSEAAFRDVDGAVVAELDKLPKFIIQRSDGGTVYMTRDIATIKFRLQEFSPSHIIYVVDARQELHFRQLFAIVRAMGYARDVELVHVPFGVITTPDGQPLSTKKGNMVYLEALLDDAVARARALVDAKSADLPLEERAAIAEAVGIGAVIYNDLYQDPRRNITLDWDRMLSIEGNSAAYLQYSHARCRSILRRAADEGVALAEADLTLLTHPSEQRLIRHLARLPEAVREAGARYAPFVIADWCYTTAREFGIFFEQCPVLRAETPALRAARLQLVAATANALRNGLALLGIQAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2791_GEOSL
Sequence: MIITTTPTIEGKRIVRYCGVVAGEAILGANLFKDLFANIRDMVGGRSATYERELQRARDIALRELEERAEELGATAVVGVDLDYEVMGQGNGMLMVSASGTAVVVE
What are the official names of this protein?
UPF0145 protein GSU2791.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: TAL2_HUMAN
Sequence: MTRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDRTLLENYQVPSPGPSHHIP
What are the official names of this protein?
T-cell acute lymphocytic leukemia protein 2, TAL-2, Class A basic helix-loop-helix protein 19, bHLHa19.
Protein: APBC_DEIRA
Sequence: MNDALLRALSTVNDPELHRDLVSLGMIERAELSGDVAQVKVNLTTPACPLKGQIELDVRSALLQVPGVRDVQIEFGAMVRAATQPALPGVKHVVLVGSGKGGVGKSSVAVNLAASLARDGARVGLLDADVYGPSVAHMLGQGQARVTANEDRKMRPIEAHGVRFISMANLSPAGQALVWRGPMLHSAIQQFLKDSAWGELDYLIVDLPPGTGDVQLSLTQTVQVTGAVIVTTPQDVALIDAARAIDMFRKASVPVLGVVENMSYFVAPDTGLTYDIFGRGGSRKLGEQYPLLGEIPLDVEVRKDADAGAPAILAHPESVAAQALRAVARTLAGQISVRTLSELPEQLPVL
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: MIAB_STRCO
Sequence: MSSIDRSQSAGGTRTYEVRTYGCQMNVHDSERLSGLLEDAGYVRAPEGADGDADVVVFNTCAVRENADNKLYGNLGHLAPKKASRPGMQIAVGGCLAQKDRDTIVKRAPWVDVVFGTHNIGKLPVLLERARVQEEAQVEIAESLEAFPSTLPTRRESAYAAWVSISVGCNNTCTFCIVPALRGKEKDRRPGDILAEVEALVAEGVSEITLLGQNVNAYGSDIGDREAFSKLLRACGNIDGLERVRFTSPHPRDFTDDVIAAMAETPNAMPQLHMPLQSGSDPVLKAMRRSYRQERYLGIIEKVRAAIPHAAITTDIIVGFPGETEEDFEQTLHVVREARFAQAFTFQYSKRPGTPAAEMENQIPKAVVQERYERLVALQEEISWDENKKQVGRTLELMVAEGEGRKDGATHRLSGRAPDNRLVHFTKPDQEVRPGDVVTVEITYAAPHHLLAEGAVLDVRRTRAGDAWEKRNTAEQAKPAGVLLGLPKIGVPEPQPVVASGCGCD
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I3B1_CONPL
Sequence: MKLVLAIVLILMLLSLSTGAEMSDNHASRSATALTDRLLGPKASICRGTGGRCTKDKHCCGWLCCGGPSVGCATSFAPCN
What are the official names of this protein?
Conotoxin Pu11.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUA_STAAR
Sequence: MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRIHKRHVRIHPSSRTDRGVHAIQQYFHFDTDLNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQQRDPFQSGLKTFIPEPLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RF3_FRATF
Sequence: MSEYLQQIAKRRTFAIISHPDAGKTTITEKMLLFGNAIKTAGTVKAKKSGIHATSDWMEMEKQRGISITTSVMQFPYNGRIINLLDTPGHEDFSEDTYRTLTAVDSALMVVDAVKGVEDRTIKLMNVCRLRDTPIVTFMNKFDRDTRDPLELLDEVENILKIKCAPMNWPIGMGKYFKGVYDLYNDEVTLFETGHGHEIYPYKKIKGLANAKDSIGIDLYEDLEMEIDLVRGASHEFDEQEFLEGNLTPVYFGTALSNFGVKEMMDGFTRYAPAPQHREADQRVVAADEQKLTGFVFKIQANMDEKHRNRIAFFRICSGKYEKGMKIFHERTGKQMQISKALTFMAGEREQVEEGYAGDIIGLHNHGSIQIGDSFTQGEKLKFKGIPNFAPEIFKRVKLNDPLKMKALQKGLVQLSEEGATQVFKPFISNDLVLGAVGVLQFDVVAQRLASEYNVKCSYEGVNVTLARWIFCNDEKKLNDFKKKYEVNLAYDGAGYLTYLAPTGVNLQLAQEKNPDIIFSATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALM2_EMIHU
Sequence: MGSASSKTRKDKAKSSTIAACPTDTAAAKACPTRLDDGLAQVAMFAGLRQVTMGVLRIDYDYQTNLGDILDPRSFDFRLVSATVEGLTFKRAQEGEPLPCYVMSNLDGAVKKLIDAGADFIVGDCGFLVYWQVYVRDFAQQYAGGRACPVMLSSLVLSLPLLATIPVGGKIGILTASKGSLMKMQKKLASVIELQKEEARTRAVPAAVQPSGIEINFSDPRFKVVGLDTVNSFKTALADDSGVDDRRSIAIEIAKYCKQVACEDPAICAWLIECTEAGGFSWAIKLGTGLPVWDPVTIGRFLSLGFTSSLPSVALTLGETGQVALDPNETDVSKGRPTKAEHRFGPEFEEMLQ
What is the function of this protein?
Mediates cleavage of dimethylsulfonioproprionate (DMSP) into dimethyl sulfide (DMS) and acrylate.  DMS is the principal form by which sulfur is transported from oceans to the atmosphere and is a key component of the ocean sulfur cycle.
What are the official names of this protein?
Dimethylsulfonioproprionate lyase 2, DMSP lyase 2, Dimethylpropiothetin dethiomethylase 2.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family. ALMA1 subfamily.
Protein: ODP2_BOVIN
Sequence: VETDKATVGF
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RPIA_LACLS
Sequence: MENLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRVAEEQLEITGVTTSSVTSEQAKALGIPLASIDEVDYVDLTVDGADEIDSHLNGIKGGGAALLMEKIVATYSKDYIWIVDESKLSENLGSFKVPVEVIRYGSEQLFKEFERAAYAPTWRLNEEGEKLITDMQHFIIDLHIAKIENPQKLADELDLMVGVVEHGLFNDMVKKVIVAGSDGVKIISQ
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PQQA_VARPS
Sequence: MKWETPTATDLRFGFEITMYVSAR
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: SBT44_ARATH
Sequence: MAKGTTFIFLFSSLLVLSLSSVSADKDDHGDQQVYIVYLGSLPSREEYTPMSDHMSILQEITGESLIENRLVRSYKKSFNGFAARLTESERKRLAGMERVVSVFPSRKLKLQTTSSWNFMGLKEGIKTKRTRSIESDTIIGVIDSGIYPESDSFSDQGFGPPPKKWKGTCAGGKNFTCNNKVIGARDYTAKSKANQTARDYSGHGTHTASIAAGNAVANSNFYGLGNGTARGGVPAARIAVYKVCDNEGCDGEAMMSAFDDAIADGVDVISISIVLDNIPPFEEDPIAIGAFHAMAVGVLTVNAAGNNGPKISTVTSTAPWVFSVAASVTNRAFMAKVVLGDGKILIGRSVNTYDMNGTNYPLVYGKSAALSTCSVDKARLCEPKCLDGKLVKGKIVLCDSTKGLIEAQKLGAVGSIVKNPEPDRAFIRSFPVSFLSNDDYKSLVSYMNSTKNPKATVLKSEEISNQRAPLVASFSSRGPSSIVSDILKPDITAPGVEILAAYSPDSSPTESEFDTRRVKYSVLSGTSMACPHVAGVAAYVKTFHPQWSPSMIQSAIMTTAWPMNASGSGFVSTEFAYGSGHVDPIDAINPGLVYELTKADHINFLCGLNYTSDHLRIISGDNSTCTKEISKTLPRNLNYPTMSAKVSGTKPFNITFQRTVTNVGMQKSTYNAKVVKFPGSKLSIKVSPRVLSMKSMNEKQSFMVTVSSDSIGTKQPVSANLIWSDGTHNVRSPIIVYAMS
What are the official names of this protein?
Subtilisin-like protease SBT4.4, Subtilase subfamily 4 member 4, AtSBT4.4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCAR_SHIBS
Sequence: MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPVLLETEARVLTADESKS
What are the official names of this protein?
UPF0434 protein YcaR.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: ACH10_HUMAN
Sequence: MGLRSHHLSLGLLLLFLLPAECLGAEGRLALKLFRDLFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENVEWRVLGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAFHLPADSGEKVSLGVTVLLALTVFQLLLAESMPPAESVPLIGKYYMATMTMVTFSTALTILIMNLHYCGPSVRPVPAWARALLLGHLARGLCVRERGEPCGQSRPPELSPSPQSPEGGAGPPAGPCHEPRCLCRQEALLHHVATIANTFRSHRAAQRCHEDWKRLARVMDRFFLAIFFSMALVMSLLVLVQAL
What is the function of this protein?
Ionotropic receptor with a probable role in the modulation of auditory stimuli.  Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.  The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane.  In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing.  This may protect against acoustic trauma.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-10/CHRNA10 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: EGGS_SCHMA
Sequence: YGYDKYGYDKYGYDKYGYDKYGYDKYGYEKGYDKYGYDKYGYEKYGYDKYGNEKYGYDKYGDDKHGHGKDYEKYGYTKEYSKNYKDYYKKYDKYDYGSRYEKYSYRKDHDKHDHDEHDHHDDHHDHRHHHHEHDHHHHHEHDHKNGKGY
What are the official names of this protein?
Putative eggshell protein.
Protein: 8ODP_MOUSE
Sequence: MSTSRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELLEESGLSVDTLHKVGHISFEFVGSPELMDVHIFSADHVHGTPTESEEMRPQWFQLDQIPFADLWPDDSYWFPLLLQKKKFCGHFKFQDQDTILSYSLREVDSF
What is the function of this protein?
Oxidized purine nucleoside triphosphate hydrolase which is a prominent sanitizer of the oxidized nucleotide pool (PubMed:11572992, PubMed:29281266, PubMed:7592783, PubMed:30304478).  Catalyzes the hydrolysis of 2-oxo-dATP (2-hydroxy-dATP) into 2-oxo-dAMP (By similarity).  Has also a significant hydrolase activity toward 2-oxo-ATP, 8-oxo-dGTP and 8-oxo-dATP (PubMed:11572992, PubMed:29281266, PubMed:7592783, PubMed:30304478).  Through the hydrolysis of oxidized purine nucleoside triphosphates, prevents their incorporation into DNA and the subsequent transversions A:T to C:G and G:C to T:A (PubMed:11572992, PubMed:29281266, PubMed:7592783, PubMed:30304478).  Also catalyzes the hydrolysis of methylated purine nucleoside triphosphate preventing their integration into DNA (PubMed:30304478, PubMed:32144205).  Through this antimutagenic activity protects cells from oxidative stress (PubMed:11572992, PubMed:29281266, PubMed:7592783, PubMed:30304478, PubMed:32144205).
What are the official names of this protein?
Oxidized purine nucleoside triphosphate hydrolase, 2-hydroxy-dATP diphosphatase, 7,8-dihydro-8-oxoguanine triphosphatase, 8-oxo-dGTPase, Methylated purine nucleoside triphosphate hydrolase, Nucleoside diphosphate-linked moiety X motif 1, Nudix motif 1.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus membrane. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein: SYGB_PSEPK
Sequence: MSAQDFLVELGTEELPPKALASLGDAFLAGIEKGLQAAGLNYTGKQVYAAPRRLAVLIRQLDVQQPDRSINIDGPPLQAAFNAEGEPTQAALGFAKKCGVELAEIDQSGPKLRFSQHIPGKATVGLLPTIVEDSLNDLPIPKRMRWAASREEFVRPTQWLVMLLGDQVVDCTILSQKAGRESRGHRFHHPENVLITTPANYVEDLRKAYVLADFAERRELISKRTAELAMQQEGTAIVPPALLDEVTALVEWPVPLVCSFEERFLEVPQEALITTMQDNQKYFCLLDSEGKLLPRFITVANVESRDPKQIVQGNEKVVRPRLTDAEFFFKQDKKQPLETFNERLKNVVFQAQLGTVYDKAERVSRLAAFIAPLIGGDAQRAGRAGLLSKCDLATEMVGEFPEMQGVAGYYYALNDGEPEDVALALNEQYMPRGAGAELPQTLTGAAVAIADKLDTLVGIFGIGMLPTGSKDPYALRRAALGVLRILIEKQLDLDLTGAVEFAVKQFGAKIKAPGLAEQVLEFIFDRLRARYEDEGIDVATYLSVRALQPGSALDFDQRVQAVQAFRKLPEAEALAAVNKRVSNLLSKAEGAIAEQVEPKYFDNANEFSLYSAIQQADQAVQPMAAARQYSESLARLAALRDPVDAFFEAVMVNAEDAKVRANRYALLSRLRGLFLGVADISLLG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_DESVM
Sequence: MSTYPLRDAVAAIATPLADALGIALWGIEIIDGGRMVLRVYVDAKPGMPVPADTAEATESATPEGVALEGSTPEGVTIDQCARLSRQLGLALDVEDVVRDAYVLEVSSPGLERPFFEIAQVVPYVGRTIELTLAVPHPEWPGRRKFRADIVRVEGDTLTFLPDTAPRPDEDPAPISVAWDDVKKAHLIHVFPDTTRPQPGGKTGQRKKAQPKKPARGGAPHDDTTD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_STRP2
Sequence: MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFEGVVIARKGAGISENYTVRKISNGIGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: BACHL_HUMAN
Sequence: MIKEAGAIISTRHCNPQNGDRCVAALARVECTHFLWPMCIGEVAHVSAEITYTSKHSVEVQVNMMSENILTGAKKLTNKATLWYAPLSLTNVDKVLEEPPVVYFRQEQEEEGQKRYKTQKLERMETNWRNGDIVQPVLNPEPNTVSYSQSSLIHLVGPSDCTLHSFVHEGVTMKVMDEVAGILAARHCKTNLVTASMEAINFDNKIRKGCIKTISGRMTFTSNKSVEIEVLVDADCVVDSSQKRYRAASVFT
What is the function of this protein?
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.
What are the official names of this protein?
Putative cytosolic acyl coenzyme A thioester hydrolase-like, Acyl-CoA thioesterase 7-like.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCR1_PICST
Sequence: MSFSRSFSRLASSKFVLPVAAAAVGLASYSFTSSSFIANEPSKAFKGGDEWIDLKLISSHDLSHDTKHLVFELPNKDDVSGLVTASLLMTKFVTPKGSNVIRPYTPVSDTEQAGTIDFVVKKYEGGKMSSHIHDLKPNDTLSFKGPFVKWKWEPNQFKSIALIGGGTGITPLYQLIHEITKNPADKTQVSLFYGSQTPDDILIKKELDALAAKHKDQVKIVYFVDKADASWKGETGYISKEFLQKNLPAPGPDNKIFVCGPPPLYKAVSGPKVSPTDQGELTGSLAELGFSKENVFKF
What is the function of this protein?
May mediate the reduction of outer membrane cytochrome b5.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, Mitochondrial cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: DAPE_BURMS
Sequence: MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLEQWRSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MKNK1_HUMAN
Sequence: MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL
What is the function of this protein?
May play a role in the response to environmental stress and cytokines.  Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
What are the official names of this protein?
MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
[Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus.
Protein: STX8_YEAST
Sequence: MDVLKLGYELDQLSDLVEERTRLVSVLKLAPTSNDNVTLKRQLGSILELLQKCAPNDELISRYNTILDKIPDTAVDKELYRFQQQVARNTDEVSKESLKKVRFKNDDELTVMYKDDDEQDEESPLPSTHTPYKDEPLQSQLQSQSQPQPPQPMVSNQELFINQQQQLLEQDSHLGALSQSIGRTHDISLDLNNEIVSQNDSLLVDLENLIDNNGRNLNRASRSMHGFNNSRFKDNGNCVIILVLIVVLLLLLLVL
What is the function of this protein?
t-SNARE which may play a role in determining the specificity of membrane fusion, protein transport and vesicle trafficking within the Golgi/endosomal and plasma membrane/endosomal systems.
What are the official names of this protein?
Syntaxin-8, SNARE protein related to mammalian syntaxin 8, ULP1-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Endosome membrane; Single-pass type IV membrane protein.
Protein: RSMG_THEVB
Sequence: MVMRNPSALLLEQFPWQETLQWQPTPQQQEQFQRFYGALLAANQGMNLTRITAVPDFWEKHLWDSLRGILPWLQPTGETLWGAKIQQVIDIGSGGGFPGVPVAIARPDWSVTLLEATQKKVKFLHSLGSAVGLANIYPEWGRAESHGRRYDLALIRAVGDVARCCAYGLPLLRSGGILVLYRGQWSDEDTQHLETLLPRYRSRRLDIQGFTTPLSHAQRHCVYLQRQG
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CHLCH
Sequence: MNLSSLRPAKGSVRNKKRVGRGQGSGNGTTAGKGNKGQQARSGYKRPIIEGGQVPVYRRLPKFGFTSRSRKTITTINLLQIEQWLEQGVVSNELTVQDFKTLLHASNTDYFKVLGAGEVTQPITITAHFFSKSAEEKIAAAGGKTIIAFRTLAEAVNIKGLPIEEALLKEKVKLVKVKKAKPTA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: UGT11_PANGI
Sequence: MKSELIFLPAPAIGHLVGMVEMAKLFISRHENLSVTVLIAKFYMDTGVDNYNKSLLTNPTPRLTIVNLPETDPQNYMLKPRHAIFPSVIETQKTHVRDIISGMTQSESTRVVGLLADLLFINIMDIANEFNVPTYVYSPAGAGHLGLAFHLQTLNDKKQDVTEFRNSDTELLVPSFANPVPAEVLPSMYVDKEGGYDYLFSLFRRCRESKAIIINTFEELEPYAINSLRMDSMIPPIYPVGPILNLNGDGQNSDEAAVILGWLDDQPPSSVVFLCFGSYGTFQENQVKEIAMGLERSGHRFLWSLRPSIPKGETKLQLKYSNLEEILPVGFLDRTSCVGKVIGWAPQVAVLGHEAVGGFLSHCGWNSTLESVWCGVPVATWPMYGEQQLNAFEMVKELGIAVEIEVDYKNEYFNMNNDFIVRAEEIETKIKKLMMDEKNSEIRKKVKEMKEKSRLAMSENGSSYNSLAKLFEEIM
What is the function of this protein?
Component of the dammarane-type triterpene saponins (e. g.  ginsenosides or panaxosides) biosynthetic pathway (PubMed:26032089).  Glycosyltransferase that catalyzes the biosynthesis of ginsenoside F1 from protopanaxatriol (PPT) and the conversion of ginsenoside F1 to ginsenoside Rg1 (PubMed:26032089).  Triggers C20-OH glycosylation of ginsenoside Rg3 to produce ginsenoside Rd (PubMed:26032089).  Mediates the conversion of protopanaxadiol (PPD) to the ginsenoside compound K (PubMed:26032089).
What are the official names of this protein?
UDP-glycosyltransferase 101, UGTPg101.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: MT1_TETTH
Sequence: MDKVNNNCCCGENAKPCCTDPNSGCCCVSETNNCCKSDKKECCTGTGEGCKWTGCKCCQPAKSGCCCGDKAKACCTDPNSGCCCSSKTNKCCDSTNKTECKTCECCK
What is the function of this protein?
The metallothioneins are involved in the cellular sequestration of toxic metal ions.  Binds 12 cadmium ions per molecule (By similarity).
What are the official names of this protein?
Metallothionein-1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 7 family.
Protein: SYA_SYNWW
Sequence: MWSSAEIRKTFLEYFEERGHSVVESSSLVPVNDPTLLFTNAGMNQFKDVFLGLDKRKYVRATSSQKCVRAGGKHNDLDTVGRTPRHHTFFEMLGNFSFGDYFKREAIGYAWEFLTEVVGLPEEKLWVTIYQDDDEAADLWPEISGIDPGRIVRLGEKDNFWSMGDTGPCGPCSEILYDRGIEYSCGAPDCGIGVCDCDRWLEIWNLVFMQFNRDESGEMTPLPRPSIDTGMGLERLSSILQGVDSNFDTDLFIPIIKRIEELTGKAYEQGERGFPFRVIADHSRACSFLIADGVLPSNDGRGYVLRRILRRALRFGRFLGIEGSFLYKNVDVVCDIMQEAYPELLEKQDFIKEVIRLEEERFLLTLNDGLKKAEEIMERARQRGDNVIPGEEAFMLYDTYGFPLDLTEDMAEENQFTLDKAGFDRSMEEQRQRARQANKGEDLLGQERLLSEKLAGIAPSSFTGYENSRDESVLLAIIKGSELMDKALNGEEVILITARTPFYAESGGQVADCGIIKGQEGLLRVQDVKKLSAWILHYGIVEGVLTTGEGVSLQLDDPARMDTARNHTATHLLHRALREVLGEHAQQKGSLVEPARLRFDFSHLKALSSEELSRIEQMVNEAIWKLYPVTTTVTALGQAREMGAMALFGEKYGEEVRVVQVDTYSSELCGGTHVQNTGQIGLFKITGEGSIGSGLRRIEAITGSYALEYIKQLEDELKKAASALRSSPLELAKRIENLNNSLKEKDKEIENLLQRLSRSSSDELVNKAFQLNDAWILIEEVDIEDPGSLRQNAEMLKDKLGRAIVMLASIKGEKVSFVCFVSKDLLEQGLHAGKIVAAAAQVAGGGGGGRPDMAQAGGRDKSKISEALAEARKMVKKTLS
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.