PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_PROM3
Sequence: MGFLPIALPFAELEVGQHLYWQIGNLQLHGQVFLTSWIVIGAILALVVVGTRKMERDPHGVQNLLEFLWDYIRDLARTQIGEKAYRDWMPFIGTLFLFIFVSNWGGSLVPWKLIHLPSGELGAPTADINTTVALALLVSLSYFYAGLSRKGLRYFEYYVHPTPIMIPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLFLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PSBJ_PROMM
Sequence: MSTKLKGPDGRIPDRLPDGSPAVSWERRWTEGSLPLWLVATVGGMAVLSVLGLFFFGSFTGVGSA
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: K2C7_POTTR
Sequence: MSVQFSSQTFSSRSAAFPRRGGQGRLSSVSSRAGSVSQMGGFGSSSLYGLGSGRPRVSVGFRSAYGGSSGGGFGARGAGLQEVTINQSLLAPLNLEIDPQIQQVRKEEREQIKTLNNKFASFIDKVRFLEQQNQMLETKWRLLQEQKSSKGSSLPAIFEAHIANLRRQLDGLQGDRGRLEGELKNMQDVVEDFKNKYEGEINKRTAAENEFVVLKKDVDNAYMNKVELEAKVDGLTDEINFLRTLYEMELNELQTQISDTSVVLSMDNSRSLDLDSIISEVKAQYEDIANRSRAEAEYQYQIKFETLQAQAGKHGEDLRSTRNEISEMNRAIQRLQAEIDNVKNQRTKLEASIAEAEERGELALKDARAKQEELEAALQRSKQERARQVREYQDLLNVKLALDIEIATYRKLLEGEESRLSGDGVGAVNISVVNSVGGSLGGGVSLGGTMGGNALGFSSGTGSTIFKTYSTRTTSSSRRSVRN
What is the function of this protein?
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.
What are the official names of this protein?
Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Type-II keratin Kb7.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: NTPB_ENTHA
Sequence: MIKEYRTIKEVVGPLMAVEKVSGVKYEELIEVRMQNGEIRRGQVLEVQEDKAMVQIFEGTSGINLKNSSVRFLGHPLQLGVSEDMIGRVFDGLGRPKDNGPEILPEKYLDINGEVINPIARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKELAAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPAIERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGYLYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELYKSGIQPPIDVLPSLSRLKDKGTGAGKTREDHAATMNQLFAAYAQGKQAKELAVVLGESALSDIDKIYAKFAERFENEYVNQGFYTNRTITETLDLGWELLAMLPRTELKRIKDDLLDKYLPEGK
What is the function of this protein?
Involved in ATP-driven sodium extrusion.
What are the official names of this protein?
V-type sodium ATPase subunit B, Na(+)-translocating ATPase subunit B, V-type sodium pump subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RPOZ_CAMLR
Sequence: MRVEQIAAKALKKLKDDRYKLALVVAKRAEELANGAEPLVNLDKNKYKYTDIALHEIAEDKIVLEGFVETSK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: VSR_PNLV
Sequence: MQNVNIPVGICNNRIVFRSLGFALSENNLTIEVLSRPIESLGRVLLFLYLYPSFAADYAQRYYGATWNQAYDISVRSLAFLLPFLFSPAVEWAVGPVFKSFVPLTELLKWSLAVGYYPTFPGSRQQLPSVPYDVNYGVQSTKAATVKLLRRAMLDDCIQSKTRLEAMLERGPDTFRNVLKAHISRIDRFTSSSGWHVADDYHMDLVLDISSGISRPSVHDNISFIQRSMRRISDILYDLCVPAHFLDLWRFTGLQCFWIDPNLGKF
What is the function of this protein?
Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Putative suppressor of silencing.
Protein: CRCB_WOLSU
Sequence: MQTLLAIFVGAGFGALLRWFLGLKLNALAPLIPLGTLGANWLGGYLIGLALAFFSTHPLLSPEWRLLIITGFLGGLTTFSTFSAEMVSLLQWGRYGALALGVALHVGGSIGMTLLGIFTFSFIQRIGG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_PERFP
Sequence: MTIIRKSHPLIKLVNHAFIDLPTPSNISGWWNFGSLLGVCLVIQISTGLFXSMHYTSDTLTAFSSVSHICRDVNYGWLIRYMHANGASLFFICLYFHIGRGIYYGSYLYMETWNIGIILLFMVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGXSVDKATLTRFFAFHFIXPFIIAAMAMVHLLXLHETGSNNPLGIPSDADKIPFHPYYSFKDLLGIVSLLSFYLTIVLFFPDAMGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVMALVLSILVLAMFPFLHTSNQRGMMFRPISQAXYWXLVSDLFILTWIGGQPVEPPFIIIGQLASIFYFSIILILLPVAGXXENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRMFO_XANP2
Sequence: MPQSADPVHVVGGGLAGSEAAWQIATRGVPVVLHEMRPQRTTDAHLTDGLAELVCSNSFRSDDPEGNAVGVLHAEMRQAGSLILTAADQNQVPAGGALAVDRDGFSRAVTKALEDHPLIEIRREELTTLPPAEWDKVILATGPLTSPALAEAVLSLTGETALAFFDAIAPIVHFDSIDMGKAWFQSRYDKPGPGGTGADYINCPLDEAQYHAFVDALIAGEKAPMRDFEAKTPYFDGCLPIEVMAERGRETLRFGPMKPVGLTNPHNPTVKAYAIVQLRQDNKLGTLYNMVGFQTKLRHGEQARVFRTIPGLENAEFARLGGLHRNTYLNSPRLLDGTLRLKADPRLRFAGQITGCEGYVESAAVGLMAGRFAAAERRGEALVPPPLTTAHGALLAHITGGHVEAEEAGAPRSFQPMNINFGLFPPLEEAPRGEPGKRLRGAEKTLAKKKAMAARALAHMAAWLDTPARAA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_XANAC
Sequence: MAKITKTFQYGKHTVTLETGEIARQAGGAVIVKVDDTVLLVTAVAAKSAREGQDFFPLTVDYQEKFYAGGRIPGGFFKREGRATEKETLISRLIDRPIRPLFPEDYKNEVQIIATVMSMNPDIDGDIAALIGASAALSLAGTPFKGPIGAAKVGYKNGEYILNPTVTELKDSQLELVVAGTANAVLMVESEAELLSEEVMLGAVTFGHREMQKVINVINELTVEAGTKPSDWVAPAKNDGMIAALKEAVGDQLASAFQVRDKLQRRDAISAIKKDVLGALAPRATIEGWAAGDLAKEFGELEYQTMRGSVLSTKVRIDGRALDTVRPISATAGVLPRTHGSALFTRGETQAIVITTLGTARDGQVIDAVSGEYKENFLFHYNFPPYSVGECGRFGAPKRREIGHGRLAKRGVLAVMPTLEEFPYTIRVVSEITESNGSSSMASVCGSSLALMDAGVPIKAPVAGIAMGLVKEGNDFVVLSDILGDEDHLGDMDFKVAGTAEGVSALQMDIKIEGITEEIMKQALQQAKAGRLHILGEMAHALTTPRQELSDYAPRLLTIKIHPDKIREVIGKGGSTIQAITKETGTQIDIQDDGTIIIASVNAIAAQAAKSRIEQITSDVEPGRIYEGKVAKIMDFGAFVTILPGKDGLVHVSQISSERVEKVGDKLKEGDLVRVKVLEVDKQGRIRLSIKAVEEGEGVQASAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRR3_RABIT
Sequence: MSSYQQKQPFTPPPQPQQHQVKQPCQPPPQDTFVPITKDPCHPNVPSPGNTNIAEQGYVKIPEQGSIKVPDTGYTKIPDSGNTKVPESGCTSVPGSGYSVVPQPGYTKVPDQGYTKVPESGCTSVPGSGYSVVPQPGYTKVPESGCTSVPGPGYPTVPQPGYTKVPESGCTSVPGSGYSVIPQPSYTKVPESGCTSVPGPGYPTVPQPGYTKVQEPNPSIVTPGLSQKKTK
What is the function of this protein?
Can serve as a substrate in transglutaminase-catalyzed cross linking reactions and can function as a cross-linked envelope precursor.
What are the official names of this protein?
Small proline-rich protein 3, Cornifin beta.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_ALIF1
Sequence: MKIDLTTLVTESRNKASENIDVLSTVEMLTVINQEDQKVALAVEAILPQIADVVDAIAVAFQSGGRLIYTGAGTSGRLGILDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRELGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMEYAKSVGATVATLSCNPNSPMTELADINMTPVVGPEVVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQKNIVIEATGCSEVEASEALSQCDNHCKTAILMVLSGLDAQSAKAKLAQHNGFIRNALSDQ
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: HEM1_SHELP
Sequence: MSLVAIGINHKTATVDLREKVAFAPDKIHEAMKSLASRTKTGEAVIVSTCNRTELYCNTGDEADVISWLESYHQLSHDDVLPCLYKYQGQQVVQHLMRVSSGLDSLILGEPQILGQVKQSFVKAKEAGTVAVTMDRLFQNTFSVAKKVRTETEIGAAAVSVAFAAVSMAKHIFSALSATKVLLIGAGETIELVARHLKDNGVDSMIVANRTISRAEAMCEEFGATAITLEQIPDFLPKADIVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEAEVADLDDAFLYTVDDLQSIIEQNMASRREAAEKAELIVEEESHHFMEWIRSLESVDSIREYRSQSMAIRDELVERAINKLAQGGDSEQLILELANKLTNKLIHAPTQALTQASRRGDLNSLGQLRAALGLDKD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: C2C2L_MOUSE
Sequence: MDPDWGQRDVGWAALLVLFAASLITVLGWMLQYARGLWLSRADGGRDSRPASAAEPGGSLRELGVWRSLLRLRATRTSTPEEAGVRGLLASLFAFKSFRENWQRAWVRALNEQACRDGSSIQIAFEEIPQLPPRASISHVTCVDQSERTMVLHCQLSAEEVRFPISVTQQSPAAVSMETYHVTLTLPPTQLEVSLEEIPDEGLLVSWAFTDRPELSLKVLPKLQTRERDEEQPELSTVEELIKDAIVSTQPAMMVNLRACSAPGGLVPSEKPPTMSQAQPSIPRPTRLFLRQLRASHLGSELGGTEELCCAAELDNPMQQKWTKPMRAGPEVEWTEDLALDLGPQSRELTLKVLRSSSCGDAELLGQATLPVGSPSRPMSRRQVCPLTPGPGKSLSPAATVTAELHYEQGSPRNLGTPTSSTPRPSITPTKKIELDRTIMPDGTVVTTVTTVQSRPRVDGKLDSPSRSPSKVEVTEKMTTVLSESSGPSNASHSSSRESHLSNGLDPVAETAIRQLTEPSGRAAKKTPTKRSTLIISGVSKVPIAQDELALSLGYAASLEASMQDDAGTSGGPSSPPSDPSATSPGPVDALSSPTSVQEADETTRSDISERPSVDDVESETGSTGALETRSLKDHKVSFLRSGTKLIFRRRPRQKEAGLSQSHDDLSNTTATPSVRKKAGSFSRRLIKRFSFKSKPKANGNPSPQL
What is the function of this protein?
Lipid-binding protein that transports phosphatidylinositol, the precursor of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), from its site of synthesis in the endoplasmic reticulum to the cell membrane (By similarity).  It thereby maintains the pool of cell membrane phosphoinositides, which are degraded during phospholipase C (PLC) signaling (By similarity).  Plays a key role in the coordination of Ca(2+) and phosphoinositide signaling: localizes to sites of contact between the endoplasmic reticulum and the cell membrane, where it tethers the two bilayers (By similarity).  In response to elevation of cytosolic Ca(2+), it is phosphorylated at its C-terminus and dissociates from the cell membrane, abolishing phosphatidylinositol transport to the cell membrane (By similarity).  Positively regulates insulin secretion in response to glucose (PubMed:24012759).  Phosphatidylinositol transfer to the cell membrane allows replenishment of PI(4,5)P2 pools and calcium channel opening, priming a new population of insulin granules (By similarity).
What are the official names of this protein?
Phospholipid transfer protein C2CD2L, C2 domain-containing protein 2-like, Transmembrane protein 24.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Peripheral membrane protein. Note=Localizes to sites of contact between the endoplasmic reticulum and the cell membrane. Embedded into the endoplasmic reticulum membrane via its N-terminal transmembrane domain and associates with cell membrane via its C-terminus. In response to elevation of cytosolic Ca(2+), it is phosphorylated at its C-terminus and dissociates from the cell membrane and localizes to the reticular endoplasmic reticulum. Reassociates with cell membrane upon dephosphorylation.
Protein: GLO2_SYNY3
Sequence: MDIHRLPALADNYIFLLHDRQRNQAAVVDPAEAKPVLDCLETLGADLVTIYNTHHHGDHVGANRELLAKYPNLEVYGGVEDQGRIPGQTVFLRDGDRLSFADREATVYFVPGHTRGHIAYYFAPGSGETIGDLFCGDTIFAGGCGRLFEGTPAQMVQSIGKLRQLPDQTRLWCAHEYTLGNLKFALTVDPSNKDLQERFQTVQGDRQRGQATIPSWLGTEKRTNPFLRWDNPAIQARVGMTEPARVFGKLRGMKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: RL29_FRATH
Sequence: MKRKDTLKDYRGKSIDQLQEVKIELLQQLFSLRMQKGTGQLKKNHLFKSAKRDIARINTIISEKNK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DXS_ARATH
Sequence: MASSAFAFPSYIITKGGLSTDSCKSTSLSSSRSLVTDLPSPCLKPNNNSHSNRRAKVCASLAEKGEYYSNRPPTPLLDTINYPIHMKNLSVKELKQLSDELRSDVIFNVSKTGGHLGSSLGVVELTVALHYIFNTPQDKILWDVGHQSYPHKILTGRRGKMPTMRQTNGLSGFTKRGESEHDCFGTGHSSTTISAGLGMAVGRDLKGKNNNVVAVIGDGAMTAGQAYEAMNNAGYLDSDMIVILNDNKQVSLPTATLDGPSPPVGALSSALSRLQSNPALRELREVAKGMTKQIGGPMHQLAAKVDEYARGMISGTGSSLFEELGLYYIGPVDGHNIDDLVAILKEVKSTRTTGPVLIHVVTEKGRGYPYAERADDKYHGVVKFDPATGRQFKTTNKTQSYTTYFAEALVAEAEVDKDVVAIHAAMGGGTGLNLFQRRFPTRCFDVGIAEQHAVTFAAGLACEGLKPFCAIYSSFMQRAYDQVVHDVDLQKLPVRFAMDRAGLVGADGPTHCGAFDVTFMACLPNMIVMAPSDEADLFNMVATAVAIDDRPSCFRYPRGNGIGVALPPGNKGVPIEIGKGRILKEGERVALLGYGSAVQSCLGAAVMLEERGLNVTVADARFCKPLDRALIRSLAKSHEVLITVEEGSIGGFGSHVVQFLALDGLLDGKLKWRPMVLPDRYIDHGAPADQLAEAGLMPSHIAATALNLIGAPREALF
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).  Is a limiting enzyme for plastidic isoprenoid biosynthesis and essential for chloroplast development.
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS, Protein CLOROPLASTOS ALTERADOS 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RL3_PELPD
Sequence: MKKGIIGKKIGMTQIFTEDGTRVPVTVIQAGPCVVTQKKTASIDGYSAVQVGFDSTPAANASKPMLGHCTKSGQGVFRYLREFKFDAASEMNLGDVLTVEQFTAGDFVDVTGTSIGKGFQGVIKRYNFRGGRASHGSRFHRAPGSIGASATPSRVFKNKKMPGQLGNTQVTMQCLQVIRVDADDNLLLIKGAIPGHRNNIVLIKNSVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: STS1_YEASV
Sequence: MGFEWGFKPSSKITQSTVSSQGTGNVMIPTAGVKQKRRYANEEQEEEELPRNKNVMKYGGVSKRRPQPGSLIRGQPLPLQRGMELMNKNQLQQLLVDLMTKHPEIQQSVHTRVIGLDFSIQKCLDMLKQKSEAVYQSIPYNRSYESNKLDDYAFVRMKPQILEFLNCLVDFILDNIPPRLENLHASLKFLDICTELVIKLPRFELASNNYYYDKCIEQLSHVWCTLIEHVARDRIILLADNSSVWKSHMTRLQVYNEHSNGLLERPLQLFKSLDMGSPSAASSSTLSLQESIIYHHDTMTANENNNNSGSAATDSPFN
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1, Dumbbell former protein 8, SEC23 suppressor 1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y4014_GEOUR
Sequence: MKIWIDADACPRVIKEMVFRASERLQVPVCLVANKDLSKAHSRLITSILVADGFDIADDYIAEHAAPEDLVITADIPLAARIVANGGVALDPRGELYTEENVGERLSIRDLMQELRSAGLVQGGPAQFGLTDRKRFASALDRTLTRMVKRKR
What are the official names of this protein?
UPF0178 protein Gura_4014.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: ACTM_STYCL
Sequence: MSDGEEDQTAIVCDNGSGLVKSGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTMYNELRVAPEEHPTLLTEAPHNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVMDAGDGVSHNVPIYEGYALPHAIARLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFEQEMATAASSTSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, muscle.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RBFA_BURO1
Sequence: MSRKRTSPNRNVQIADQIQRDLSELIMREVKDPRIGIVTIQSVELTPDYAHAKVYFTALTGDPEKTQEALNHASGHLHNLLFKRLHIHTVPTLHFHYDQTIEKAVEMSRLIKEANSTRAKDDDEADTPAKDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
Protein: TPDA2_COMSP
Sequence: MQESIIQWHGATNTRVPFGIYTDTANADQEQQRIYRGEVWNYLCLESEIPGAGDFRTTFAGETPIVVVRDADQEIYAFENRCAHRGALIALEKSGRTDSFQCVYHAWSYNRQGDLTGVAFEKGVKGQGGMPASFCKEEHGPRKLRVAVFCGLVFGSFSEDVPSIEDYLGPEICERIERVLHKPVEVIGRFTQKLPNNWKLYFENVKDSYHASLLHMFFTTFELNRLSQKGGVIVDESGGHHVSYSMIDRGAKDDSYKDQAIRSDNERYRLKDPSLLEGFEEFEDGVTLQILSVFPGFVLQQIQNSIAVRQLLPKSISSSELNWTYLGYADDSAEQRKVRLKQANLIGPAGFISMEDGAVGGFVQRGIAGAANLDAVIEMGGDHEGSSEGRATETSVRGFWKAYRKHMGQEMQA
What is the function of this protein?
Component of the terephthalate 1,2-dioxygenase multicomponent enzyme system which catalyzes the dioxygenation of terephthalate (TER/TPA) to 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylic acid (DCD).  It can also use 2,5-dicarboxypyridine (PDC) and 1,4-napthalenedicarboxylic acid (NDC) as substrates, and preferentially uses NADPH which is the physiological electron donor.
What are the official names of this protein?
Terephthalate 1,2-dioxygenase, terminal oxygenase component subunit alpha 2, TPADO terminal oxygenase component, TER dioxygenase system, TERDOS, Terephthalate 1,2-dioxygenase large subunit 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: TVB57_HUMAN
Sequence: MGPGLLCWVLLCPLGEGPVDAGVTQSPTHLIKTRGQHVTLRCSPISGHTSVSSYQQALGQGPQFIFQYYEKEERGRGNFPDQFSGHQFPNYSSELNVNALLLGDSALYLCASSL
What is the function of this protein?
Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain (PubMed:24600447).  Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
Probable non-functional T cell receptor beta variable 5-7.
What are the subcellular locations of this protein?
Cell membrane.
Protein: HLOX2_HELRO
Sequence: NNNNNINNNNSRLNIATSSSATPSTTFQQKSPYYDTTTSTTVTSLTSTDYSSYQQQQQLLLAEFDTDYKENAEQFADVSVQNVNISCSNSNNNNTDLNNNSSKCMNNSNIIIDNNSTDSFQQKQHPETTEDTKYNAETEEDRKSHGKAFGGHFASSRYGIDDDVISNRTGSRPSSPASTTPSCENFSPHSPSMKGGKMGSAPSYPWMSIVGPNSNQRRRGRQTYTRYQTLELEKEFKFNRYLTRRRRIELSHTLYLTERQIKIWFQNRRMKEKKEVQAIRELNEIEKTKIGCFGSLRSPCDDDDDDDDDIDGSGSSGVCGVASGGIGGGDCRKVSGNSGSSRNGLSSNGGNVMGGINGAGGGANVVNHDELITSCRDVPSQQNCLNGNNNNNNNINNNNINNNNGVEMMVGMVCSSGRMMMEGVDYGGG
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  May play a role in midgut regionalization.
What are the official names of this protein?
Homeobox protein LOX2.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL27_SULDN
Sequence: MAHKKGQGSTQNNRDSAGRRLGVKKYGGEVVIPGNIIIRQRGTKIHPGKNVGMGKDHTIFALVAGVVTFHRKDKKRQQVSIVPAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.