PharMolix/UniProtQA huggingface dataset:
Protein: CYMC4_MELCT
Sequence: GSIPCGESCVYIPCISSLLGCSCKSKVCYKD
What is the function of this protein?
Probably participates in a plant defense mechanism (Potential).  Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (By similarity).
What are the official names of this protein?
Cyclotide mech-4.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: MDTI_YERPS
Sequence: MQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYAMWGGFGIAATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSI_STREU
Sequence: YAPSALVLTIGQGATAAESGVQRAVTLTCTPKSSGTHPDAKGACTQLRAAGGDFDKVTRIKSDTVCTKEWNPTVVTAEGVWDGRRISYEHTFANPCMAKAGKGLVFEF
What are the official names of this protein?
Protease inhibitor SIL-V3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAAF3_XENTR
Sequence: MAAVVRRMGPVWWGLTPALDLQMHLHPPPPPEIYCSCSDDLPELNILLVGGGDGRHILKTICQASRWPHRKLKFFIIESDLELLARHMLFLSLALEHPEQMGLQEKSELFLELFGNSLIRNKTASYLQEKSELFIRYVTDPDYQQSNVPLLNLSSIKFKERDKLEDIFKFWRNADPKLFPIDKYWDEKNRQNLGRRYDSRKGAYDWDLSMKLHDRGAGVINSREYNYWREKGVAFMNREGVYDIPNKTLASQMVVPQSSGKVLARGYWGDITASPYIAFGIETEEESLLQTANGVHVKSAQDIAQHNMISLFHELAYGKIYSVPASGQAESELAKTDSDYKTNEEQTVGLITLNNVEIHFLPRFNNFFNLLYFSCSMVHFLKPEYKFIAASKATLVLELTKFMVDLQTEKLQDYVTIVAKLAQEAGFTPTETIDWKTDYIAKFERAHDS
What is the function of this protein?
Required for the assembly of axonemal inner and outer dynein arms.  Involved in preassembly of dyneins into complexes before their transport into cilia (By similarity).
What are the official names of this protein?
Dynein axonemal assembly factor 3.
What is the protein family that this protein belongs to?
Belongs to the DNAAF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle.
Protein: ATPB_LIMRD
Sequence: MSSGKVLQVIGPVVDVEFPLDEKLPEINDALKIKESDGKTLTTEVALELGDGVVRTIAMDGTDGLQRGMEVENTGASISVPVGDDTLGRVFNVLGEPVDNGPKFGPDAKRMPIHRDAPKYDDLNNATEILETGIKVIDLLAPYVRGGKIGLFGGAGVGKTVLIQELIHNIAQGHNGISVFTGVGERTREGNDMYYEMKASGVLEKTAMVYGQMNEPPGARMRVALTGLTIAEYFRDVKGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSITSIQAVYVPADDYTDPAPATTFAHLDATTNLERRLTQIGIYPAVDPLASTSTALTPEIVGKEHYEVATQVQHVLQRYHELQDIISILGMDELSDEEKTIVARARRIQNFLSQSFSVASQFTGLPGKYVPLKETIKGFKEILAGKYDDLPEEAFRLVGPIEDVVEKAKKMKAETDEDSSED
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MIAA1_AZOPC
Sequence: MELQEYELITVLGPTASGKTAFATRLANELNSEIISADSRQVYRNMTIGTGKDLDNYIIEGKFIPYHLIDICQAGEKYNVFRFQHDFHEIFTKIKKKGKLPILCGGTGLYIESVLKGYKLLDVPENLILRSNLKDKSVDELKKILKSYKNLHNQTDTDSVRKIIRAIEIETCYPTQKNNPINSYSSIKSLIIGVNIDRELRRNRISLRLKKRLEEGMIEEVKNLLETELSPDQLIYYGLEYKYITLYLIGQLSYSEMYQQLEIAIHQYAKRQMTWFRGMERRGFKIHWIDVYEMNHLNEIFNRIHF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRMD_NEIM0
Sequence: MLIQAVTIFPEMFDSITRYGVTGRANRQGIWQFEAVNPRKFADNRLGYIDDRPFGGGPGMIMMAPPLHAAIEHAKAQSSQTAKVIYLSPQGKPLTHQKAAELAELPHLILLCGRYEGIDERLLQTSVDEEISIGDFVVSGGELPAMMLMDAVLRLVPGVLGDMQSAEQDSFSSGILDCPHYTKPLEFQGMAVPEVLRSGNHGLIAEWRLEQSLRRTLERRPDLLEKRVLIPKESRLLETIRQEQREIQS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXDBA_DANRE
Sequence: MTDYDDRNNCASNMYLPYYVSTPDFSSVSSFLPQTTSCQVNFPYSSNIAQVQPVREVTFRDYGLDHPSKWHYRGNYASYYSTEEIMHRDLLQSTNRAEMIFKNDSMYSHHAGTNSSCSFFTNVGRNGVLPQGFDQFFETANSEKPNPEQSKQKPDTSVPGDAACNPSTDSAEQTKQDPTDTVEEESSVSTCDEEKNSGSSATKSRKKRCPYSKYQIRELEREFFFNVYINKEKRLQLSRMLSLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D11a, Hox-D11, Homeobox protein Hox-C11.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASSY_YERPN
Sequence: MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRB_ACIS7
Sequence: SHKVSGGLHGVGVSVVNALSSKLQLTIHRAGQIHEQEYQHGDPQYPLKVVGETSTTGTTVRFWPSGDTFSQTIFNVDILARRLRELSFLNAGVKIVLRDERVNFEHIYAYEGGLSEKSALDIAGLPGKLADCQEKDPALSELYLVEGDSPGGSAKQGRNRKMQAILPLKGKILNVERARFDKMISSQEVGTLITALGCGIGREEYNPDKLRYHKII
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1MA4_LOXDE
Sequence: WIMGHMVNAIAQIDEFVNLGANSIETDVSFDKNANPEYTYHGIPCGCGRTCTKSEKFNVFLQGLQKATTPGDSKYQEKLVLVVFDLKSSSLYDNQASDAGKKLAKSLLQNYWKNGNNGGRAYIVLSIPNLAHYKLITGFKETLKTEGHPELMEKVGYDFFGNDDIDQVAKAYKKAGVTGHVWQSDGITNCLPRGLDRVKQAVANRDSSNGFINKVYYWTVDKRSTTRGALDAGVDGIMTNYPDVIADVLSESAYKSKFRIATYEDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LdSicTox-alphaIB3aiv, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RUTF_ECO10
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: ARMX5_HUMAN
Sequence: MVDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPEVRDKVIRLILKL
What are the official names of this protein?
Armadillo repeat-containing X-linked protein 5.
What is the protein family that this protein belongs to?
Belongs to the eutherian X-chromosome-specific Armcx family.
Protein: DAPEL_LACAC
Sequence: MTVLSEKELIQIRRHLHEIPELALQEKETHDYLLKVIKNLKQDHLTIVVPKTLPTAILGLVKGINPKKTIGYRTDIDALPVQEKTGLPFTSKHSGIMHACGHDIHMTVALGLLSYFSENQPKDNLLFFFQPAEESESGGKQAYEKGLFQGKFKPDEFYGLHDNPELPAGSIGCRMGTLFAGTTEINIDVIGKSGHAAFPQNANDTVVAAANLIMQIQTIISRSIDPIQSGVITLGKVNAGVIRNVIAGHTRIEGTIRGLTQKMILQIDRRLQDVCDGIAHSYNVEVNLELNQGGYWPVENDPKITKNFISYMKKNPKVNFIETEPKMTGEDFGFLLAKFPGTMFWLGVGDPSSQLHSSTLNPDEKSIQSGIDAIKGFLIDRMG
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: Y3228_PHOPR
Sequence: MVSPLPLNKRQQGQVYEVMAEQYLQRHHLKPVERNFTCRSGEIDLIMRDKSCVVFVEVKFRKQNHFGSAAEAVNWRKQQKLKRAALLWLKKNSLSTEHTEFRFDVVAIQGPDQQIEWFTNTLVEG
What are the official names of this protein?
UPF0102 protein PBPRA3228.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: HACE1_CHICK
Sequence: MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKVRKVYDVVRKIDVKEMNFTKHAFINQTSHEQEPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWLKNTEYTSGYERGDQVIQWFWDVVEELTQEERVLLLQFVTGSSRVPHGGFAHIMGGSGLQNFTIAAVPYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
What is the function of this protein?
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases.  Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion.  Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division.
What are the official names of this protein?
E3 ubiquitin-protein ligase HACE1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, HECT-type E3 ubiquitin transferase HACE1.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane. Cytoplasm. Endoplasmic reticulum.
Protein: ZSC12_GORGO
Sequence: MASTWAIQAHMDQNEPLEVKIEEEKYTTRQDWDLRKNNTHSREVFRQYFRQFCYQETSGPREALSRLRELCHQWLRPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPGEQVSVHTGEQEMFLQEMVPLRKEGEPSMSLQSMKAQPKYESPELESQQEQVLDVETGNEYGNLKQEVSEEMEPHGNTSSKFENDMSKSARCGETREPEEITEEPSACSREDKQPTCDENGVSLTENSDHTEHQRICPGEESYGCDDCGKAFSQHSYLIEHQRIHTGDRPYKCEECGKAFRGRTVLIRHKIIHTGEKPYKCNECGKAFGRWSALNQHQRLHTGEKHYHCNDCGKAFSQKAGLFHHIKIHTRDKPYQCTQCNKSFSRRSILTQHQGVHTGAKPYECNECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLIQHQRIHTGEKPYKCDVCEKAFIQRTSLTEHQRIHTGERPYKCDKCGKAFTQRSVLTEHQRIHTGERPYKCDECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQRKKTSYKEILLKNHSEPQAGVNLLLSSLIPEWQSCFRKDL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 12, Zinc finger protein 96.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MVD1_CANAL
Sequence: MYSASVTAPVNIATLKYWGKRDKSLNLPTNSSISVTLSQDDLRTLTTASASESFEKDQLWLNGKLESLDTPRTQACLADLRKLRASIEQSPDTPKLSQMKLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYELPQDMSELSKIARKGSGSACRSLFGGFVAWEMGTLPDGQDSKAVEIAPLEHWPSLRAVILVVSDDKKDTPSTTGMQSTVATSDLFAHRIAEVVPQRFEAMKKAILDKDFPKFAELTMKDSNSFHAVCLDSYPPIFYLNDTSKKIIKMVETINQQEVVAAYTFDAGPNAVIYYDEANQDKVLSLLYKHFGHVPGWKTHYTAETPVAGVSRIIQTSIGPGPQETSESLTK
What is the function of this protein?
Diphosphomevalonate decarboxylase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (PubMed:12073030).  MVD1 converts diphosphomevalonate into isopentenyl diphosphate (PubMed:12073030).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase ERG12 first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase ERG8.  The diphosphomevalonate decarboxylase MVD then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase IDI1 then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase ERG20 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (Probable).
What are the official names of this protein?
Diphosphomevalonate decarboxylase, Mevalonate pyrophosphate decarboxylase, MPD, Mevalonate-5-diphosphate decarboxylase, MDD, MDDase.
What is the protein family that this protein belongs to?
Belongs to the diphosphomevalonate decarboxylase family.
Protein: P3_RDVF
Sequence: MDSTGRAYDGASEFKSVLVTEGTSHYTPVEVYNILDELKTIKITSTIAEQSVVSRTPIPLSKIGLSDVKKLFDINVIKCGSSLRIVDEPQVTFIVSYAKDIYDKFMCIEHDSAYEPSLTMHRVRVIYSMLNDYCAKMISEVPYESSFVGELPVKSVTLNKLGDRNMDALAEHLLFEQDVVNAQRENRIFYQRKSAPAVPVTFGDDLEPAVRERANLYHRYSVPYHQIELALHALANDLLSIQYCHPTVVYNYLSSRAPNFLRLDDQVSLKLTSAGIGTLMPRPVVQLLDYDLVYMSPLALNNLASRLLRKISLHLVMQMVTAVQQDLGEVVSVSSNVTNPASACLVRMNVQGVQTLAVFIAQSMLNPNISYGMLSGLTLDCFSNFIYGACLMLFQALIPPSALTARQRLDINNRFAYFLIKCHATQATTASVVPNQVIYPVDAIDQWQSNRRDVLVAIYNNLLPGELVLSNLIQTYFRGNTAQQAAEILIPADQTSYGANETRALSAPYLFGAPINMLAPDARLSTYKRDLALPDRSPILITTVEGQNSISIEILRHKTGLIRAMYLNGFVTQPPAWIRNANSNTALLSRFLDVTPNLLGIYEAILANTYANAVNVYCDSVYRADIPTEWKLHQSVDPQDLLFGVFGIVPQYQILNEAVPDFFAGGEDILILQLIRAVYDTLSNKLGRNPADIFHLDEVFKVIEEIVSVLVQQKVDARKYFTESMRSGSFSKPRWDNFLRRPVAQRLPNLDSVIMTQADHVYNYMTQLTHIIPITDCFYIVKNSGFVDRGSTGPVMASSSVYENVLKVVHTIADFEAANALRLQRRSVDNTSYTDSLSDMFNGLRSISSSEFVRSVNGRSVFTEGRIDAIKVNMRVKFDLQFITEEGGYSKPPNVKKLMFSDFLSFLDSHKSDYRPPLLTVPITIGLNNLGETNSNTLRMRSEAIDEYFSSYVGAQILVPINVVDTRVYTEFSELRNFFTGDVVITDDPFDVWDGVKATYIPIGVHGVRLDPNGDQPPL
What is the function of this protein?
Capsid protein which self-assembles to form the inner icosahedral capsid with a T=2 symmetry, and consisting of 60 P3 dimers.
What are the official names of this protein?
Outer capsid protein P3, Core protein P3.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus inner capsid protein P3 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Found in the interior of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: VINT_BPHC1
Sequence: MAVRKDTKNGKWLAEVYVNGNASRKWFLTKGDALRFYNQAKEQTTSAVDSVQVLESSDLPALSFYVQEWFDLHGKTLSDGKARLAKLKNLCSNLGDPPANEFNAKIFADYRKRRLDGEFSVNKNNPPKEATVNREHAYLRAVFNELKSLRKWTTENPLDGVRLFKERETELAFLYERDIYRLLAECDNSRNPDLGLIVRICLATGARWSEAETLTQSQVMPYKITFTNTKSKKNRTVPISKELFDMLPKKRGRLFNDAYESFENAVLRAEIELPKGQLTHVLRHTFASHFMMNGGNILVLKEILGHSTIEMTMRYAHFAPSHLESAVKFNPLSNPAQ
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: PYRG_SHEPA
Sequence: MTTRYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMNRRNNFTTGRIYEEVLRKERRGDYLGATIQVIPHITNAIKEKVLAGGEGHDVAIVEIGGTVGDIESLPFLESIRQLGVELGRDRTLFMHLTLVPFLGAAGEVKTKPTQHSVKELRSIGIAPDVLVCRGDRAIPANEKAKISLFCNVEERAVISLKDVDSIYKIPALLKAQGLDQLVTKRFGIDCKEADLAEWEKVVYQEANPVGEVTIGMVGKYIELPDAYKSVNEALKHAGLFNRVSVNIKYIDSQNVEAKGDEVLQGLDGILVPGGFGERGVEGKIMAAKFARENNLPYFGICLGMQVALIEFARHVAGLEGAHSTEFKPETPHPVVGLITEWINEDGQVEERHEESDLGGTMRLGAQLCHLEEGTKAAAAYKSTTCVERHRHRYEVNNNYKERLEKAGLIFSGLSSDRSLVEMIELPNHPWFVAGQFHPEFTSTPRDGQPLFEGFVAAAAAYQKRDLED
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: YCF76_ORYSJ
Sequence: MKKILFSMFYSILVGEEPDSVFLKKEGKQNQVKMIWVAPSSCAKDLTISEGTGATFLFNFHSRVSYLFPRPFLRPRNMKWTNSFS
What are the official names of this protein?
Uncharacterized protein ycf76, ORF85.
What is the protein family that this protein belongs to?
Belongs to the ycf76 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEM6_BURM7
Sequence: MTDSTYDVNRVRAYLQGLQMRIADALGAFDGTPLAADTWRRGPGERLRGGGCTRILEAGGFFERAGIGFSDVAGDALPPSANASRPQLAGRGFEALGVSLVLHPRNPYCPTVHMNVRMLIATKPGEAPVFWFGGGMDLTPIYGFEEDARHFHRTCRAALEPFGAELYPRFKKWCDDYFFLKHRNEARGIGGIFFDDFSELGFERSFEMLQSVGDAFLPSYLPIVERRRDTPYGERERAFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILLSMPPTAGWRYDWHPDPGTPEARLQSEFLVPRDWA
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NASP_BOVIN
Sequence: MAAESTATAAITAELVSADKIEEDAPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEEESLVENNDNIDEEAREELREQVYDAMGEKEAQKTEDKSLVKPEMDKEQETEMEKGGREDMDIGEPAEELQEKVKSAPDQLTETTEEGKGAAAPEGLSEAEVTSKKPDQEIPGAEEGKSVSETDVQEECREKGGQGEVIVSIEEKPKEASKEQPVVTLEKQGTPVEIEAVKPVDMGGDEPKEQVAASESERGKAILEQLVGQELPSAEESPEVTTQAADASAAEAGSEVSEKPGGQDTVLPQDGAVNGLSAAGDHASTKPQTNAEGLIGTKDGSALEKVRAELVPSQETKLSVEESEAAGDGVETEVAQGATEQSPEDKVKIAANEEAQDKEEQMKEGEETEGSEEEDKENDKAEETLNDSALENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQDTKEAQLYAAQAHLKLGEVSVESENYLQAVEEFQACLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEKRMAVLNEQMKEAEGSPTEYEKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPSGGSSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDTISTGTEVAENMEEEAENKAESRAAVEGTVEAGATVESTAC
What is the function of this protein?
Required for DNA replication, normal cell cycle progression and cell proliferation.  Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity.  NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
What are the official names of this protein?
Nuclear autoantigenic sperm protein, NASP.
What is the protein family that this protein belongs to?
Belongs to the NASP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LPXC_AZOVD
Sequence: MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFRRIDLDPVVDIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSAPEVPIMDGSAGPFVFLIQSAGLQEQEACKRFIRIKREVAVEEDDKRAVFLPFDGFKVSFEIDFDHPVFRGRTQTASIDFSSTSFVKEVSRARTFGFMRDIEFLRSHNLALGGSVDNAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNRLLRALLEQKDAWEVVTFEDAMSAPISYVRPIAAV
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: MGSA_LISMC
Sequence: MHIALIAHDEKKDLMVGFATAYKHLLEPHQLYATGTTGLRIIEATGLTVHRFKSGPLGGDQQIGARISENKMDLVIFLRDPLTAQPHEPDVTALIRLCDVYEIPLATNIGTAEILIRGLGAGFLDWRDLRRNDE
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: ATPE_RHOPS
Sequence: MATFHFDLVSPEQVAFSGEVDQVDIPGAEGDFGVLAGHAPVVAVIRPGILTVTAGGAQQKIVVLGGIAEVSEKGLTVLADVATAVADLDMQDFAATIATMEQQLPGKVGDVLDRSIERLDHYKSIQHQISTTAMH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.