PharMolix/UniProtQA huggingface dataset:
Protein: RL20_BACSU
Sequence: MPRVKGGTVTRKRRKKVLKLAKGYFGSKHTLYKVANQQVMKSGNYAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKLSGIEVNRKMLADLAVNDLTAFNQLADAAKAQLNK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RLMM_SHEB2
Sequence: MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDLPENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVGYSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDNGPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILETMQTILKENGVTDFKVQCKHLYHDRDEVTVHLWLRPNTAWN
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_HAMD5
Sequence: MSDIIKQIEEEQMKKDVPAFRPGDTLEVKVWVIEGTKKRLQAFEGFVIAIRKRGLNSAFTVRKISNGEGVERVFQTHSPIIDSITVKRRGAVRKAKLYYLRELTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SFH5_SCLS1
Sequence: MSAEVDTNIPKENVPEEVVEAKTTTTTTTMEPEPLIVEDLKSTTIESTPVKIGDPTSNEQIAREEPKPTITEPSTTKSVAAEPTTEQHQETAVKLESVKEADAEAAARVESTEDADGEKALSTSQPSVSFDKTTKTHDGSPLSKFFSELPEILKVAGHNEMWGIILDPSEDHVQTSIVLEKFLRANTKDVTKAKAQLTEALKWRKAMQPQKLLVDTEFDKVKFGKLGYVTSYPTSEGGKEVITWNIYGAVKDTKKTFSDVPEFLRWRAALMELSIRELDLASATEKIPENGPDPYRMIQVHDYLNVSFLRMDPGIRAASKETIQTFSMAYPELLKEKFFVNVPMVMGWVFTAMKIFLSADTIKKFHPLSYGSDLGAEIPGIAEKLPKEYGGKGEELESGFTVKYSGDDVPKSD
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.  Heme-binding protein that may play a role in organic oxidant-induced stress responses.
What are the official names of this protein?
Phosphatidylinositol transfer protein sfh5, PITP sfh5.
What is the protein family that this protein belongs to?
Belongs to the SFH5 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: APBC_AQUAE
Sequence: MAVQDVIEALKKETLEDVGINQNLAQLVKDIKMVGNVLTIVFEPPKQGLEDIIRAKVIDALGNLPEVQKIDVKFVKPQAQIPVKQQAPQQQQTPPPQTQQPMFTRKKVPGVKHIIAVGSGKGGVGKSTVAANLAVALSQLGYKVGLLDADVYGPSVPTLFGLKGERVTVDQFQRIIPVEKYGLKILSIGFMLPSEDTPIIWRGPMLMKALTEFLFSTKWGNLDFLVMDLPPGTGDVQITLAQNVELTGAVVVTTPQDVALADVKKAVSMFREVNIPVLGVIENMAYFICPSDKQKYYIFGKGKVAEFANAYGLKILGSIPIDPEVAEKSDKGEPIVISHPDSEVAKAFLSIAKVLSQVVESKVN
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: RS15_CLOPS
Sequence: MDKIRKQEIIAKHARHEGDTGSPEVQIALLTERINSLTDHLRTHKKDHHSRRGLLMMVGQRRGLLNYLYEQDIERYRAIIKELGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MIAA_BACC0
Sequence: MGEVQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTKEEVDGIPHYMVDIKNPEESFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDAIYREQMEKLALERGVEYVHKKLQEVDPESAERIHANNVRRVIRALEIFHTSGEKMSDQLEKQENELLYDVSLIGLTMDREMLYDRINLRVDIMMDQGLLEEVEGLYNRGIRDCQSIQAIGYKEIYDYFEDRVSLEEAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYXEGKLQLKSNNSK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: Y1730_STRSV
Sequence: MIEREERVGLIVYLYYNRDAKKLANFGDIIYHSKKHRYLHLYVNQEDAQNLQENLPKERYVKQVRISHIKELDQNFVGSLYREQENVII
What are the official names of this protein?
UPF0298 protein SSA_1730.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPA_HUMAN
Sequence: MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP
What is the function of this protein?
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen.  By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events.  During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (By similarity).
What are the official names of this protein?
Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: DEOC_BACC4
Sequence: MNIAKLIDHTILKANSTKEDVMKVIEEAKEYKFASVCINPTWVKLAADELAGHDVDVCTVIGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDADKMVAAGASRVGASASVAIVLNDAKGATDNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_BACCZ
Sequence: MKHAENEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHNNNIWNEWAFKSWVESDEYTGPDMTDFGLRSQQDEEFKVQYDKQMELFKKNVLEDDDFSNKYGYLGDVYGKQWRAWKTTAGETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTHLIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC_CERCA
Sequence: MVVKAVCVINGDVKGTVHFEQQDAKSPVLVTGEVNGLAKGLHGFHVHEFGDNTNGCTSAGPHFNPYGNSHGAPSDLNRHLGDLGNIEASGDGATKVEISDKLITLFGENSIVGRTIVVHADPDDLGKGGHELSKTTGNAGARLGCGVIGICKI
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn], Superoxide dismutase 1.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_SYNR3
Sequence: MAHPPLEPIEALASATAQSLGFLMESVVLHSHRAPQALIVAVRKGDGSDVNLDDCASFSQAFGEALETGELLTGAYVLEITSPGLGDVLQQDRDFRSFRGFPVCVRQRDAKGGEIQREGTLLGRDADAVELNLRGRIQRIPRSDVLEVRLTSPSA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHO_TRIV2
Sequence: MPVKKGEMVRAIREKLENSVEATASDTRFPAYLFETKGEVVDIKGDYALVMFGQVPTPNIWLRLDQIESF
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y951_METJA
Sequence: MLIGEIMDLNLKNFLEDREEIIRDAKRKDEKSFKDFKKIVEEIKERENKDKIVCDFTEYNPLHKGHKYALEKGKEHGIFISVLPGPLERSGRGIPYFLNRYIRAEMAIRAGADIVVEGPPMGIMGSGQYMRCLIKMFYSLGAEIIPRGYIPEKTMEKVIDCINKGYHIQVKPYKIICIETGEILGEKLNIDNYVIASMSQMIYKLNREGLKFNPKFVFVKRLEGISGTKIREAIFSGKFEDIKNMLPKTTLSILKELYDNGKLNELILKRFEDRILETANEYDLYEYLPSNVAEILEKKRPFNNIEEIKNSLPYGFSRHFRERILSKLEARIPNETLSKYINNYPAKIKILAVKL
What are the official names of this protein?
Uncharacterized protein MJ0951.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
Protein: NUON_CAMJR
Sequence: MLNNFLNLELLNISLSYPFLFLITTAIVLLLCSGFWKFHRSFYIGISSLSLIVSAFLILNNANAQGLEAKAFLATLNNDIVSFYASLVILCFSFLYLLMQKEENQGEFYALFLFMIASLLLMVSSSNLVLIFIGLESSSLALYTLIAMRGSDNAISSAIKYFSIAAVGAGFFVMAVAFIYLKTGTLDLSANLALKNEFQKDPMLLGAGVMIFVLCAIKLSLAPFHFWLKDVYYAAHTNLVAFISVVPKVAMLVVVIRLFDFLNNTGFEYIIIVLAIFSMLIGAFAALSQNNIKKMFAYSSVVHSSLVLIACIPLLKEQNFDGILLAIFGYWTLFAFANYAVFMILSNYENNSYESLNGLLVKKPLIAFCLSISVLSLAGIPPFGVFWGKFMILNTVILNGYWYLALFVALSSVIMLYAYLKILIHVLFMKNDRVYNIKFSFIQNFILAFCVCVSIFAILLML
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPD_PECCA
Sequence: MQATLIKPTIFTHQPILEKLFKSQSMTQEESXQLFAAIV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ERLL3_ARATH
Sequence: MASKNSTSLALFFALNILFFTLTTATDCRCNLSPKPRTVPSPKVPSPKYPSPSIPSPSVPTPSVPTPSVPTPSVPSPNPTPVTPPRTPGSSGNCPIDALRLGVCANVLSGLLNVQLGQPSAQPCCSLIQGLVDLDAAICLCTALRANVLGINLNVPISLSVLLNVCNRRLPSDFQCA
What is the function of this protein?
Probable lipid transfer protein (LTP).  May improve freezing survival.
What are the official names of this protein?
pEARLI1-like lipid transfer protein 3.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family. PEARLI1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SYA_RICTY
Sequence: MTKFTTEEVRSKFITYFKANNHTHVPASSLIPDNDPSLMFVNSGMVQFKNVFTGQEKRSYNKAVTSQKSLRAGGKHNDLEHVGYTARHHTFFEMLGNFSFGDYFKEQAIYYTWDLLTKEFELPKDKLYVTIYHTDDTAASYWEKISGLRDDRIIKIKTNDNFWSMGDTGPCGPCSEIFYDHGEEIYGGLPGTKDEDCDRFIEIWNMVFMQYEQINKETRIELPKKSIDTGMGLERMTAVLQHVNNNYDIDLFQEIINFTENIVKVKVDGEAKFSYRVIADHLRASSFLIADGIIPSNEGRGYVLRRIMRRAMRHAHMLGAKEPLMYKLLPKLVDLMGNIYPELKIAEGFISSILEQEEIRFKTTLERGLKLLTEETKTLTKGNKLSGEVAFKLYDTYGFPLDLTEDILKNRDIAVDHKGFEELMLIQKERARTSWLGSGESKTDQLWFDIKEQYGSTEFLGYTLNEAKCKIIALIKNNNLADTIQEVDTQFLLIANQTPFYGESGGQMGDIGMIFSQDSEVEVIDTLKYLRSIIVHKCILKKGKINIGENANFNIDIKYRKNLRIHHSATHILHAVLHKILGKQVIQKGSLVTSTYLRFDINHSKAITNEEITLIEDKVNEIIRNNHEVNTTVMFTEDAIKQGAIALFGEKYDSEVRVVKIGETSLELCCGTHVKRTGDIGAFKIISESSIAAGVRRIEAVCGEFVIKLIREKDNLIKLIESSVKTNKNELITKVTNILERNKELEKELEKAHLAGLDLSIEQIKKQAEQIAGIKLLYKKVGNINNKILRQAAENLTQKLENLIVVYIAHGVGKLSITVAVSKAITDKFNAGIIAKELSLFLGGSGGGGKASIAQSGGNDIVNLTNINKKLLSLIVT
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCA_ECOLU
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PININ_PONAB
Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEIEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDNECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQPQHQPQLQLQSQSQPVLQSQPPSQPENLSLAVLQPTPQVTQEQGHLLPERKEFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRGDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR
What is the function of this protein?
Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'.  Capable of reversing CTBP1-mediated transcription repression.  Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  Participates in the regulation of alternative pre-mRNA splicing.  Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites.  Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets.  Involved in the establishment and maintenance of epithelia cell-cell adhesion (By similarity).
What are the official names of this protein?
Pinin.
What is the protein family that this protein belongs to?
Belongs to the pinin family.
What are the subcellular locations of this protein?
Nucleus speckle. Cell junction, desmosome. Note=Cell-cell contact area, predominantly desmosome of intercellular adherens junction. Not a nucleocytoplasmic shuttling protein (By similarity).
Protein: CLC9_ANOGA
Sequence: MCILTLVERKHLKNMVHVRLLVMMHILIIYSTFGAVRRPINIRVLEGNSCDTPQVIGGKCMNISLCDPAFVHSIAYQEHTPVCQQNAFYRVICCQPFLDFCENSKQFQIMHGIEAEPGMFPHLARLGLKSEEDGIAWTCSANIISERFLLTAAHCNPVNIAGLGCAESMQCDQQNTVKSFISNPKYKTSFKYHDIALVELEQNIRFNKRVLPICPYISKTDLHESEDLVIAGWGATESHFQSPRLMFATVRTVLQNDCKDHYASLLKASPNKKLHQGITDEMYCAQGALVDNVTEYIDACSGDSGGPLQTKQNNNLYLIGVISTGFGCGSSSPGLYTRVASYFGWIKETVSATRDN
What is the function of this protein?
Probable serine protease which plays an essential role in the innate immune response against bacteria and protozoa infection by activating the melanization cascade (PubMed:33045027).  In the susceptible strain G3, appears to be dispensable for ookinete elimination which occurs by lysis (PubMed:33045027).
What are the official names of this protein?
CLIP domain-containing serine protease C9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the hemolymph (PubMed:33045027). Recruited by CLIPA8 to microbial surfaces where it is cleaved into the two chain active form (PubMed:33045027).
Protein: PMT3_ARATH
Sequence: MKGRSDGGQKKRVIALVCVAAVVLVFVYLFYGSSDHRASAIEYGRKLGLGGDDDDTKQDDTSSSFGVDDGFTPRSFPVCDDRHSELIPCLDRNLIYQMRLKLDLSLMEHYERHCPPPERRFNCLIPPPNGYKVPIKWPKSRDEVWKVNIPHTHLAHEKSDQNWMVVKGDKINFPGGGTHFHYGADKYIASMANMLNYPNNVLNNGGRLRTVFDVGCGVASFGGYLLSSDILTMSLAPNDVHQNQIQFALERGIPASLGVLGTKRLPYPSRSFELSHCSRCRIDWLQRDGILLLELDRVLRPGGYFAYSSPEAYAQDEEDLRIWREMSALVERMCWKIAAKRNQTVIWQKPLTNDCYLEREPGTQPPLCRSDNDPDAVWGVNMEACITSYSDHDHKTKGSGLAPWPARLTSPPPRLADFGYSTGMFEKDTELWRQRVDTYWDLLSPRIESDTVRNIMDMKASMGSFAAALKEKDVWVMNVVPEDGPNTLKLIYDRGLMGAVHSWCEAFSTYPRTYDLLHAWDIISDIKKKGCSEVDLLLEMDRILRPSGFIIIRDKQRVVDFVKKYLKALHWEEVGTKTDSDSDQDSDNVVFIVQKKLWLTSESLRDME
What are the official names of this protein?
Probable methyltransferase PMT3.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: GCST_YERE8
Sequence: MAKQTPLYDQHVACGARMVDFHGWMMPLHYGSQIDEHHIVRQDAGMFDVSHMTIVDLHGARTREFLRYLLANDVAKLTQPGKALYTAMLNASGGVIDDLIVYFLREDYFRLVVNSATREKDLNWIIQHAEPYQVDVTVRDDLALVAVQGPTAQQKVATLLTSEQQQAIAGMKPFFGIQADDLFIATTGYTGEAGYEIALPKERVVEFWQQLLAAGVKPAGLGARDTLRLEAGMNLYGQEMDEGVSPLAANMGWTVAWLPEDRQFIGREALEQQRANGTEQLVGLIMTEKGVLRNELPVHFSDDSGNQHVGVITSGSFSPTLGFSIALARVPAGIGENAVVQIRNREMPVRVTKPGFVRAGKPVAL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RECA_METNO
Sequence: MAQSSLRLVENPTMDKDKSKAIDAALAQIERAFGKGSIMRLGKGDKVQEVETISTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLALHTIAEAQKKGGVCAFVDAEHALDPVYARKLGVNLDDLLISQPDTGEQALEITDTLVRSGAIDVLVVDSVAALTPRAEIEGEMGDQQPGLQARLMSQALRKLTGSISRSNCMVIFINQIRMKIGVMYGSPETTTGGNALKFYASVRLDIRRVSTLKDRDEPIGNSVRVKVVKNKVAPPFKQVEFDIMFGEGVSKVGELIDLGVKAGIVEKSGAWFSYDSQRLGQGRENAKGFLRDNPDIAGRIEAAIRQNMGLVADKILENAVPTAEDYDEGAA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALT7_ALTAL
Sequence: MFRPDLDDIPALGSETSSLDNTVENGNYRVKLWRDKSGIRSPPSTFCTWFKQYQIGLSLGSLLLLILMFTCLPYYDNVSGTYTRGRDDLAFIFSGVVLFTALRAISMIYLLEPLARLCGVHKKLMVRFTEQGWLVIHHSLFWTTGMYINYNSEYWMDLDGVWSGFPERTMTGLTKGYYLLQLAFWLQQIVVVNFEKRRKDYSQMLTHHLITSVLLATSYSYYQTKVGNVILCLVDIVDVLFAFAKLLKYLGFQYACDVAFCVFLASWLVARHGLYLLVCWSIFTILPTVMPYGCYDTISGNRLSEFPADGGNEIMREVLQAFRDPGGPVCFNSRIGWAFLGLLVGLQVLMLIWLGMILKVAYKVFQGEGADDTRSDSEESGYGTSDHEGDCYGAQAGNPKVIRQFVASREKVHIEQAENQGLHLRQQKRSAR
What is the function of this protein?
Sphingosine N-acyltransferase-like protein; part of the gene cluster that mediates the biosynthesis of the host-selective toxins (HSTs) AAL-toxins, sphinganine-analog mycotoxins responsible for Alternaria stem canker on tomato by the tomato pathotype (PubMed:18435561, PubMed:19749175, PubMed:19449880).  The biosynthesis starts with the polyketide synthase ALT1-catalyzed C-16 carbon chain assembly from one starter acetyl-CoA unit with malonyl-CoA extender units (PubMed:18435561, PubMed:19449880).  ALT1 also selectively transfers methyl groups at the first and the third cycle of chain elongation for AAL toxin (PubMed:19449880).  The C-16 polyketide chain is released from the enzyme by a nucleophilic attack of a carbanion, which is derived from R-carbon of glycin by decarboxylation, on the carbonyl carbon of polyketide acyl chain (Probable).  This step is probably catalyzed by a pyridoxal 5'-phosphate-dependent aminoacyl transferase ALT4 (Probable).  The respective functions of the other enzymes encoded by the cluster have still to be elucidated (Probable).  The sphingosine N-acyltransferase-like protein ALT7 seems not to act as a resistance/self-tolerance factor against the toxin in the toxin biosynthetic gene cluster, contrary to what is expected (Ref. 6).
What are the official names of this protein?
Sphingosine N-acyltransferase-like protein ALT7, AAL-toxin biosynthesis cluster protein 7.
What is the protein family that this protein belongs to?
Belongs to the sphingosine N-acyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.