PharMolix/UniProtQA huggingface dataset:
Protein: G6PD_CYBJA
Sequence: SYDSFGDRVTIIVFGASGDLARKKTFPALFGLFREKQLPSTVQIIGYARSHLSDKDFKDYISSHFKGGDDKTKEDFLNLCSYISDPYDTDEGYKKLEARCQEYESKHNVKVPERLFYLALPPSVFHTVCEQVKKNVYPKNEKSRIIIEKPFGRDLETYRELQKQISPLFTEDEVYRIDHYLGKEMVKNLLVLRFGNELFSGIWNNKHITSVQISFKEAFGTEGRGGYFDNIGIIRDVMQNHLLQVLTLLTMERPVSFDPEAVRDEKVKVLKAFDKIDVNDVLLGQYGKSEDGTKPGYLDDSTVKPNSKAVTYAAFRVNIHNERWDGVPIVLRAGKALDEGKAEIRIQFKPVAKGMFKEIQRNELVIRIQPNEAIYLKINSKIPGISTETSLTDLDLTYSTRYSKDFWIPEAYEALIRDCYLGNHSNFVRDDELEVSWKLFTPLLEAVEKEENVKLESYPYGSKGPKELRKYLIDHGYVFNDPGTYQWPLTNTDVK
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity).
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: PRP2_LOTGI
Sequence: MNLKVGIAVLIIALIVPSAQPYIYRGYDRSSDPNFDMFGRSVAGDNAYRQPLRTLQSPAPMVPRAMPLQRQMYVPPRAPMIAPRVPIRAPMSPVRPGVLQTQPVMPIPYHHPHYYPGYDPPSYDPPDISQPDPPGEYFYHPRPRPNLGIYNPSRITAFNRAYLR
What are the official names of this protein?
Proline-rich protein 2, Uncharacterized shell protein 21, LUSP-21.
What are the subcellular locations of this protein?
Secreted.
Protein: SYA_PYRIL
Sequence: MLSAKVLLNSNFLRKQCPLCKSYFWTRRADQIYCGDQPCVPYGFIGNPPTKTSIESPAELRERFLRFFERNGHVRIKRYPVVARWRDDVYLVGASIYDFQPWVTSGAVPPPANPLVISQPSIRLTDVDKVGRSGRHLTGFEMMAHHAFNYPDKYVYWIDETTQYAYEFFTKELGIPQDEITFKESMWEGGGNAGECFEVLVRGLEVATLVFMHYEVKDGKYVELPLKIVDTGYGLERIYWLLKGTPTIYDAVFSHYLAKVRQKVGIPEPPADIMGRASIYFGQMDPEVIGLDKAYDIIAEKIGVDPKWLREVVRPQEALYVLADHSRTVSWMIADGVIPSNTGAGYLARLLIRRILKNLRVVGIDAPLVELFDMHLAELKREYPEIWAARDLILELVDLEEKKYREVLKSAPAAVKKALEEARRRGRAGLDTDDLVALYDSQGIPPEIVAEVAKSLGAEVKVPDDFYTKLAARHAKREKKPESPLVEMSKVADLPRTRELFYEDSYMRSFKARVLRVIDGRYVVLDQTAFYPEGGGQPADRGVLKFQGGEAKVVDVQRVGHVVVHVVEGQLPPEGAEVVGEIDWERRYSLMKMHTGTHVLIQSIRRVLGPHIWQAGAQKDIPSSRLDVTHYKLPTAEEIAKIEELANKVVQENLPVYVKIMPRNEAEAKYGFILYQGGVVPTREIRVLQIGPDEEPFDIQACGGTHLRSTGEIGLIKIQKVERIADGVVRFVFTTGMHALAYIQELERKLAEAAHIIGGSREEFVESVKKLLQRAEEAERRAKHYAELYAAVVAENLRAEQIGKYRVAVVELNDDELAKHIALAATRRDKDLVLVFVGGDRVTIYTGGVDVTPVVKTLREAGFRGGGSKTFAQGLYKGDIQTLKEALKKALS
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOIAD_STRRI
Sequence: MKALVFEAPERALLTHRDIPDPAPGEALVRIAYNSVCGSDLSFYKGVWHGSTYPVVPGHEWSGTVVDVNGPLGAELIGTNVVGDLTVSCGTCAHCTARTPTLCEDLGELGFTRDGACAEYMTIPVGNLRRLPDTLPLRAACQVEPLAVALNAVDRLGVTAGEKVAVMGAGGIGLLLAQAVRLRGGSVTAVAEPVPERRAAALALGVPAAVSGEPGALVELTRTHPDAVPDVVLEASGYPTAVQESLEAVRPGGRVGLVGYRIGETAVMAPHHIVLKVLTIRASMGPGTRFEEAIEVLASGAVTVDALLSHEFALDDYAKALDVALRRADSNTRSYFNLQA
What is the function of this protein?
Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD(+) or NADP(+), forming 3-amino-2,3-dideoxy-scyllo-inosose (amino-DOI).
What are the official names of this protein?
2-deoxy-scyllo-inosamine dehydrogenase, DOIA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. DOIA dehydrogenase subfamily.
Protein: YSCI_YEREN
Sequence: MPNIEIAQADEVIITTLEELGPVEPTTEQIMRFDAAMSEDTQGLGHSLLKEVSDIQKTFKTAKSDLHTKLAVSVDNPNDLMLMQWSLIRITIQEELIAKTAGRMSQNVETLSKGG
What is the function of this protein?
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function.
What are the official names of this protein?
Yop proteins translocation protein I.
What is the protein family that this protein belongs to?
Belongs to the YscI/HrpB family.
Protein: RUVA_RUEPO
Sequence: MIGKLTGRLDYRSTDHVLIDVRGVGYIVYCSDRTLAALPGVGEVVALYTDMVVREDLMQLFGFMSLAEKEWHRLLCSVQGVGAKVSLAILGALGPDGVSRAIALGDWASVKSAKGVGPKTAQRIVLDLKDKAPGVMAMGGTVAQAMEGAVEVVEVIEPAAPAPRKAAPPGGAGAATAGALSALSNLGYGPSDAAAAVAQAAAEAPEAGETDLIRAALRLLAPKT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RS6_DEIDV
Sequence: MNQYDLNLILNPNLSAEQVQIEKDYIETALKNVGAEVSNLDDLGNRRLAYQVGKDREGYYLMYTIKAGGNPEKDIASSLRLRDHVRRVLVVKDRPEWKTKKA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: APT_LISMC
Sequence: MEIKDLQDYVAIVNDWPKKGIVFKDITPLMNDGEAYRFATDKIVEYAKELKIDIIVGPEARGFIIGCPVAYALGIGFAPVRKPGKLPRETIEMEYDLEYGTNKLSMHSDAIKPGQRVLITDDLLATGGTIEATIKLVEELGGIVAGCAFLIELKELEGHKKLNGYDRLILMQL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPDL_CLODC
Sequence: MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLLDVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQKTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNVVSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFDSGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVIQVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLTYTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCIDCFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLYDEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCLETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFEPHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKGQHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKDALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEEAQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYALFESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSETLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV
What is the function of this protein?
Glycyl radical subunit of the HPA decarboxylase that decarboxylates phenylacetates with a hydroxyl group in the p-position.  Active toward 4-hydroxyphenylacetate and 3,4-dihydroxyphenylacetate, forming 4-methylphenol and 4-methylcatechol, respectively.  Is likely involved in the catabolism of aromatic amino acids such as tyrosine fermentation.  4-methylphenol (p-cresol) formation provides metabolic toxicity, which allows an active suppression of other microbes and may provide growth advantages for the producers in highly competitive environments.  The large subunit is the catalytic subunit that binds the substrate.
What are the official names of this protein?
4-hydroxyphenylacetate decarboxylase glycyl radical subunit, HPA decarboxylase glycyl radical subunit, 4-hydroxyphenylacetate decarboxylase catalytic beta subunit, 4-hydroxyphenylacetate decarboxylase large subunit, p-hydroxyphenylacetate decarboxylase large subunit.
What is the protein family that this protein belongs to?
Belongs to the glycyl radical enzyme (GRE) family. HPAD subfamily.
Protein: GATC_AEDAE
Sequence: MFRHIFTLGPRSISAITVRSRRALSSTAKPVSAPVTSDDRPNLDVKHLKHPTKVPQQPHKSDIDRRQEPVPRISVDDQTVQLLERLSLVDLDSKEAHRTLEDSIEFASRILAIDTDGVEPLYTVLEKQKLALREDVVSDGNLQEDVLSNARITEEEYFVAPPGNIPLEQDSSGNKHKQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial, Glu-AdT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KCY_STAES
Sequence: MSSINIALDGPAAAGKSTIAKRVASRLSMIYVDTGAMYRAITYKYLQNGKPENFDYLINNTKLELTYDEVKGQRILLDNQDVTDYLRENDVTHHVSYVASKEPVRSFAVKIQKELAAKKGIVMDGRDIGTVVLPDAELKVYMIASVAERAERRQKENEQRGIESNLEQLKEEIEARDHYDMNREISPLQKAEDAITLDTTGKSIEEVTNEILSLL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_HYPNA
Sequence: MADLLIELFSEEIPARMQAKAEADLLAALTGKLKEAGLAWKTAFAVSGPRRLTAVVEGLDARSADVREEKKGPKVGAPEQAIAGFLRGAGLTDISEASVVSDPKKGDFYVAYSTVPGRDAKDVIAEAVPAIIRDFHWPKSMRWGTGELRWVRPLQRIVCVLDGAVVPFEVGGITSGNETEGHRVHGRGPYTVTGWADYKSQLEGQGHVVLSRDDRRAAILGGIEKACAKAGLQWIEDKGLLEEVTGLAEWPVVVLGQMDPDFLDLPPEVITLSMRTHQKYFAATHAKTGKLAPNFILVANIAATDGGAKIAEGNARVLSARLSDARFFWEKDKATPLEVMGEKLKTIAFKEELGSLGDKVERVAALARELAPAVGADPGLAERAARLAKADLVSEMVGEFPELQGVMGRYYALAVGEDARVADAIRDHYKPQGPSDSVPTDPVSIAVALADKLDTLVGFWAIDEKPTGSKDPFALRRAALGVVRINLENGVRLKLSNAILKAPLAVRPVVKGGQSDSVRSAASKAIDALIDPTLLSFFADRLKQVLRDQGKRHDLIDAVFALGEDDLVLIVKRVEALAAFLATEDGATLLAGYRRAANILKAEEKKGALPDGLSVDPALIAKGPAAEQALWASLNETTAALEAPLKTEDFAGAMTALAGLRAPVDAFFEDVLVNDSDAKVRENRLALLIAVRGALHKVADFSRIEG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERD_XANAC
Sequence: MQPADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRDGAGGGLLGIDRAALFDYLRWRTRANYSPRSTARLLSTLRAFYGLCLRDGARSDDPTALIDPPHLPRSLPKALTESQIEALLAAPDLDTPAGLRDRAMLELMYAAGLRVSELVNLPAVGVNLRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDVSRQPLSRQQFWALVKRYAAVAGIDPATVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLSTTQIYTLVARQHLQKLHASHHPRG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_CORGL
Sequence: MISIGTDLVHISAFAEQLAQPGSSFMEVFSAGERRKANERQASRYAEHLAGRWAAKESFIKAWSQAIYGQPPVIAEEAVVWRDIEVRADAWGRVAIELAPELAAVVRESIGEFSSSLSISHDGDYAVATCVLTIQ
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_SALDC
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTIPDAMGLGLYFEAGEGPRFTAPVTCKADVEKLPIPDPEGELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHLLLDKLAKSVTLYLNAQIKAGAQSVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRCVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGHKVALQGNMDPSMLYAPPARIEDEVATILAGFGQGEGHVFNLGHGIHQDVPPEHAGAFVEAVHRLSAQYHN
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNA_FUSSH
Sequence: MATSAPVTSRTETLAKYLKLDQKGQIMAEYVWVDAAGETRSKSRTLPEKDYKAEDLPVWNFDGSSTNQAPGDNSDVYLRPCAVYPDPFRGSPNIIVLAECWNAGGTPNKFNFRHDCVKVMDTYAEDEPWFGLEQEYTLLGPDNRPYGWPTGGFPAPQGEYYCGVGTGKVVQRDIVEAHYKACLYAGIQISGTNAEVMPAQWEYQVGPCLGIEMGDQLWVSRFFLARITEEFGAKVSLHPKPIAGDWNGAGLHSNFSTKAMREEGGMKVIEEALKKLEPHHAECIAEYGEDNELRLTGRHETGSIDSFSWGVANRGTSIRAPRETAAKGYGYFEDRRPASNADPYRVTKALLQFSLA
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPB_ECO81
Sequence: MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: PROF1_PHLPR
Sequence: MSWQTYVDEHLMCEIEGHHLASAAILGHDGTVWAQSADFPQFKPEEITGIMKDFDEPGHLAPTGMFVAGAKYMVIQGEPGRVIRGKKGAGGITIKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLVEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-1, Allergen Phl p 11, Pollen allergen Phl p 12.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CSN7_ARATH
Sequence: MDIEQKQAEIIDQLVKRASTCKSEALGPLIIEATSHPSLFAFSEILALPNVAQLEGTTDSVYLDLLRLFAHGTWGDYKCNATRLPHLSPDQILKLKQLTVLTLAESNKVLPYDTLMVELDVSNVRELEDFLINECMYAGIVRGKLDQLKRCFEVPFAAGRDLRPGQLGNMLHTLSNWLNTSENLLISIQDKIKWADNMSEMDKKHRKEAEEGVEEVKKSLSMKGDVDIRGNKEMFGEPSGVMDYEEDGIRPKRRRHPVTR
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes.  The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.  Regulates the TSO2 subcellular localization.  May be involved in nucleic acid binding.
What are the official names of this protein?
COP9 signalosome complex subunit 7, CSN complex subunit 7, Protein FUSCA 5.
What is the protein family that this protein belongs to?
Belongs to the CSN7/EIF3M family. CSN7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CALM_PNECA
Sequence: MSNEQNLTEEQISEFKEAFSLFDKDGDGSITTKELGIVMRSLGQNPTEAELQDMVNEVDADGNGTIDFPEFLAMMARKMKDVDSEEEIREAFKVFDKDGNGIISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGVIDYSEFVKMMLSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: THIC_ECOLU
Sequence: MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSKEQPQFEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGLLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSVQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CYAY_PSEFS
Sequence: MSLTEARFHDLVDSTQQALEDIFDDSGLDVDLENSAGVLTVKFESGQQLIFSRQEPLRQLWLAARSGGVHFDYDEESGKWQCDKSEELLSEMLARLVSEYTGADLDFDEI
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: SODC_CHICK
Sequence: MATLKAVCVMKGDAPVEGVIHFQQQGSGPVKVTGKITGLSDGDHGFHVHEFGDNTNGCTSAGAHFNPEGKQHGGPKDADRHVGDLGNVTAKGGVAEVEIEDSVISLTGPHCIIGRTMVVHAKSDDLGRGGDNESKLTGNAGPRLACGVIGIAKC
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PVK2_EUBPO
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, EubPo-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG_SALA4
Sequence: MSGQPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIDIDFIRISGLRGKGVKALLAAPLRIFNAWRQARAIMKRFKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNQWLAKIATTVMQAFPGAFPNAEVVGNPVRTDVLALPLPQVRLAGRDGPIRVLVVGGSQGARVLNQTMPQVAARLGDTVTIWHQSGKGAQLTVEQAYAGAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPAIFVPFQHKDRQQYWNALPLENAGAAKIFEQPQFTVEAVADTLAGWSREALLTMAERARAVSIPDATERVASEVSRVART
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MCAL_HALMA
Sequence: MTRLCRTFQTAPAAIPNDNSAKFLVSGLTSKGFQAPDWLVPDIEDGTAPSMKDEAVDNIIEHIPDHADDFAGDILPRVEWAYDDANARERGIEQVTRLAEAVGEELDGFVFPKVGRLDDVRDAAGVIADAERDAGLPEGTLEMAIILETAPGRSDLREICQYATDSRLSGLVFGPVDYTAELGGRTLDGERPRWDGLLEALSNETSAADIVAIGGPFDQLFHERAGVTYYNAEGYADQVAYEATIGIDGSWSLHPKQTEQANRIHMPTVEEMERDLHKIESFNEAKREGTGAVVVDGQMVDEATYKNFANTVKTVRAIDETHPAQTEAYYDDDLLARARDVELIFG
What is the function of this protein?
Involved in the methylaspartate cycle.  Catalyzes the reversible cleavage of beta-methylmalyl-CoA to propionyl-CoA and glyoxylate, as well as the reversible cleavage of (S)-malyl-CoA to acetyl-CoA and glyoxylate.  In addition, it has a small malyl-CoA thioesterase activity.  It can also catalyzes the cleavage of (S)-citramalyl-CoA to acetyl-CoA and pyruvate.
What are the official names of this protein?
L-malyl-CoA/beta-methylmalyl-CoA lyase, (3S)-malyl-CoA/beta-methylmalyl-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: LFG3_MOUSE
Sequence: MSNPSAPPPYEDHNPLYPGSPPPGGYGQPSVLPGGYPAYPAYPQPGYGHPAGYPQPVPPVHPMPMNYGHDYNEEERAGSDSFRPGEWDDRKVRHSFIQKVYCIISVQLLITVAIIAIFTFVEPVGKYVRNNVAVYYVSYAVFLVTYLTLACCQGPRRRFPWDIILLTIFTLALGFVTGTISSMYENKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLMVTGIVTSIVLIFKYIYWLHMVYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIVYIFTFVLQLVGSRD
What is the function of this protein?
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
What are the official names of this protein?
Protein lifeguard 3, Responsive to centrifugal force and shear stress gene 1 protein, Protein RECS1, Transmembrane BAX inhibitor motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the BI1 family. LFG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Lysosome membrane. Endosome membrane.
Protein: LFTR_PSEPK
Sequence: MLTWLTRDSLTFPPLEKALHDPNGLLAAGGDLSPERLVQAYRHGCFPWYQDGQPILWWSPDPRTVLLPDQLHVSRSLAKLMRQGRYQVSFDTDFPAVIAACAAPRDYADGTWITDTMRNAYCELHRRGIAHSVEVRQDGELVGGLYGLAMGQLFFGESMFSRADNASKVGFVTLVNHLRDAGFVLIDCQMPTNHLHSLGAHAISRAEFASYLARHLDQPNSASWVA
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1627_METJA
Sequence: MSKESKITLIGSKLAKTGGEFIYLGEIEECKNCKFKRLCHGNLEVGRKYKIVSVRSANHPCIVHEGGVKVVEVVLADLTIMIESKKALEGVVLNHEPITCDNFDCEYYSFCNSEGIKEGEKYKIKQVLNEKINCPFGNSLKKVIVELVENK
What are the official names of this protein?
UPF0179 protein MJ1627.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.