PharMolix/UniProtQA huggingface dataset:
Protein: GSPI_AERHY
Sequence: MNARGMTLLEVMVALAVFAIAGLAVMKTASEHLSALNYLEEKTLATWVVENQLVQQKLEAKWPGDSWVEGGEQMAGQTWYWRYRGVATADNNFKALDMEVRTAPKAESPVAFIRTYISR
What is the function of this protein?
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
What are the official names of this protein?
Type II secretion system protein I, T2SS minor pseudopilin I, General secretion pathway protein I.
What is the protein family that this protein belongs to?
Belongs to the GSP I family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL10A_BOVIN
Sequence: MSSKVSRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y504_METJA
Sequence: MKLFDYPGIQNTDETLKIAVERAKKGDIKSIVVASSTGYTAKKLLDLLEKEGLDLNVVVVTYHQGFHGEDTISMDKEVEEELKKRGAKVFRGSHALSGVERGISNKLGGYGPVQVIAETLRTFGQGVKVCYEITIMACDAGLIKAKEEVIAIGGTGRGADTAMVIKPANMNTFFNIEAREILCMPRIKKKVKEDDE
What are the official names of this protein?
Uncharacterized protein MJ0504.
Protein: ANMK_PECAS
Sequence: MRSGRYIGVMSGTSLDGVDVVLAAIDEHTVAQQARYCHPIPQDIKMAILGMCQGQAVTLSALGQLDTRLGILFAEAVLTLLKETGLRAQGITAIGCHGQTVWHEPTGEAPCTLQIGDNNRVAALTGITTIGDFRRRDLAYGGQGAPLVPSFHHALLLHPVERRIVLNIGGIANLSLLVPGAPVRGYDTGPGNMLLDAWIWRHCAQPYDKDALWAINGQANPLLLRRMLTDPYFALRAPKSTGREYFNLGWLERMLAGLPPIAPQDVQATLVELTAISIADQVLLVGGCERLLVCGGGAHNPLIMARLSALLPGIEVSTTDECGVNGDDMEALAFAWLASRTLSGLPGNLPSVTGASQETVLGAIYPVNVD
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: SYH_SALTI
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGAEVFGLQGPDIDAELIMLTARWWRALGISEHVSLELNSIGSLEARANYRDALVAFLEQHQETLDEDCKRRMYTNPLRVLDSKNPDVQALLNDAPVLGDYLDDDSREHFAGLCKLLDAAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFIASPVVDIYLVAAGAQTQSAAMTLAERLRDEMPGVKLMTNHGGGNFKKQFARADKWGARIALVLGESEVADGTVVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_BACLD
Sequence: MSDRQAALDMALKQIEKQFGKGSIMKLGEQTETRISTVPSGSLALDAALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQQQGGQAAFIDAEHALDPVYAQKLGVNIDELLLSQPDTGEQALEIAEALVRSGAVDIVVIDSVAALVPKAEIEGDMGDSHVGLQARLMSQALRKLSGAINKSKTIAIFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRRAEQLKQGNDVMGNKTKIKVVKNKVAPPFRTAEVDIMYGEGISKEGEIIDLGTELDIVQKSGAWYSYQEERLGQGRENAKQFLKENKDILLMIQEQIREHYGLDTGGAAPAQEDEAQAQEELEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C78A3_SOYBN
Sequence: MTSHIDDNLWIIALTSKCTQENLAWVLLIMGSLWLTMTFYYWSHPGGPAWGKYYTYSPPLSIIPGPKGFPLIGSMGLMTSLAHHRIAAAAATCRAKRLMAFSLGDTRVIVTCHPDVAKEILNSSVFADRPVKESAYSLMFNRAIGFASYGVYWRSLRRIASNHLFCPRQIKASELQRSQIAAQMVHILNNKRHRSLRVRQVLKKASLSNMMCSVFGQEYKLHDPNSGMEDLGILVDQGYDLLGLFNWADHLPFLAHFDAQNIRFRCSNLVPMVNRFVGTIIAEHRASKTETNRDFVDVLLSLPEPDQLSDSDMIAVLWEMIFRGTDTVAVLIEWILARMALHPHVQSKVQEELDAVVGKARAVAEDDVAVMTYLPAVVKEVLRLHPPGPLLSWARLSINDTTIDGYHVPAGTTAMVNTWAICRDPHVWKDPLEFMPERFVTAGGDAEFSILGSDPRLAPFGSGRRACPGKTLGWATVNFWVASLLHEFEWVPSDEKGVDLTEVLKLSSEMANPLTVKVRPRRG
What are the official names of this protein?
Cytochrome P450 78A3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: MET3_ASPTN
Sequence: MANSPHGGVLKDLLARDAPRHDELAAEAETLPAIVLSERQLCDLELIMNGGFSPLEGFMTQKDFDGVCENCRLADGHLFSMPITLDASQQVISDSNLKPGSRVTLRDFRDDRNLAILTIEDIYRADKEKEAKLVFGGDPEHPAIKYLNTKVEDFYIGGKIEAVNKLNHYDYVALRYSPAELRVHFDKLGWTRVVAFQTRNPMHRAHRELTVRAARARQANVLIHPVVGLTKPGDIDHFTRVRAYQALLPRYPNGMAVLGLLPLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKNSKGEEFYGPYDAQHAVEKYREELGIEVVEFQQVTYLPDTDEYKPKDEVPAGIKTLDISGTELRNRLRTGAHIPEWFSYPEVVKILRESSPPRATQGFTIFLTGYMNSGKDAIARALQVTLNQQGGRSVTLLLGDTVRHELSSELGFSAEDRHTNVQRIAFVAGELTRAGAAVIAAPIAPYERSRKAAREAVSGLGGSFFLVHVNTPLEYCEKTDKRGIYAKARRGEIKGFTGVDDPYEAPENADLVVDVSKQSVRSIVHEIILMLESEGYFDRL
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUCB2_HUMAN
Sequence: MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKAKLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYENIIALQENELKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI
What is the function of this protein?
Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner.  May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
What are the official names of this protein?
Nucleobindin-2, DNA-binding protein NEFA, Epididymis secretory protein Li 109, Gastric cancer antigen Zg4, Prepronesfatin.
What is the protein family that this protein belongs to?
Belongs to the nucleobindin family.
What are the subcellular locations of this protein?
Golgi apparatus. Membrane; Peripheral membrane protein. Cytoplasm. Secreted. Endoplasmic reticulum. Nucleus envelope. Note=Golgi retention is mediated by its N-terminal region. SUBCELLULAR LOCATION: [Nesfatin-1]: Secreted.
Protein: DENR_CRYNJ
Sequence: MASAVSGPSTKQVHPFYCAVCSLPTEYCEFGPSVSKCKAWLEEQDKDEYERVWGEGALASRIGTLSLDKQEKLEADAAKLEKKAAKKAEAEAKKKEQTKIIIKRSERTKRKHQTHIQNLELFGVDLKKAAKQFAGKFATGSSVSKTPQGEEEIVIQGDVGDEIVEMIRQQVGALKGVPADQITRVEVKKKKEAEEPAA
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT_HELPY
Sequence: MDNTLKHLAIIMDGNGRWAKLKNKARAYGHKKGVKTLKDITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKMLKKYLKDERSTYLNNNIRFRAIGDLEGFSKELRDTILQLENDTRHFKDFTQVLALNYGSKNELSRAFKSLLESPPSHINLLESLENEISNRLDTHDLPEVDLLLRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFGELKC
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: LECS_STYJP
Sequence: MATSNSRPHLLQTHKPFSVVLAISITFFLLLLNKVNSAEILSFSFPKFASNQEDLLLQGDALVSSKGELQLTTVENGVPIWNSTGRALYYAPVHIWDKSTGRVASFATSFSFVVKAPVASKSADGIAFFLAPPNNQIQGPGGGHLGLFHSSGYNSSYQIIAVDFDTHINAWDPNTRHIGIDVNSINSTKTVTWGWQNGEVANVLISYQAATETLTVSLTYPSSQTSYILSAAVDLKSILPEWVRVGFTAATGLTTQYVETHDVLSWSFTSTLETGDCGAKDDNVHLVSYAFI
What is the function of this protein?
Mannose/glucose-specific lectin.
What are the official names of this protein?
Seed lectin, LECSJASG.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: RSMH_LIGS1
Sequence: MAEFKHITVLLNEAVDGLNIKPDGTYVDCTLGGGGHSGLILSKLSENGKLYSFDQDITAINFNKDKFEEENELGKINFIKSNFRNISEELNKRNILGVDGILYDLGVSSPQFDNADRGFSYNYDAPLDMRMDQSQSLTARDVVNDWSYEQLVRIFFRYGEEKFAKSIARRIEKVRQQTPIETTGQLVDLIKEAIPAKARRKGGHPAKKTFQAIRIAVNDELGALEESLEQALDLLNPGGRISVITFQSLEDRLVKVMFKQKTSLPELPPGLPVIPDSQKVEYKLITRKPIVPSEDEITHNNRAHSAKLRIIEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_ALIFM
Sequence: MLEDLRLYQLISPSLPVGSFTYSQGLEWAIEKGWVTNVTELKHWLSNQLMDSLATLELPVLAKLTQLLQQEEWQQAQEWCDFIIANRETKELRLEERQRGLAFSMLLPKLGIELNQTTLPMVKQTQVAAFALAANHWNLTPTKLAAAYAWGWLENAVIVGIKLVPLGQSAGQQLLLEMADVIPQAVEKSQHWPEHLIGSFTPAQVLASSRHESQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL39_THEKO
Sequence: MARNKPFAKKLRLAKAAKQNRRVPVWVIVKTNRKVITHPKRRHWRRTKLKE
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: Y356_LIMF3
Sequence: MAEQLEVVIITGMSGAGKTVAVQSFEDLGYFVIDNMIPSVATKFVDAVKQSGEITRMAMVMDSRSRGFYDQVVPCVAQLRGRSDLTLRLLFLEATDEELVSRYKESRRAHPLSHQDGVLPGIMRERQLLNDLKSQADLVVDTTTLTPRQLKQRITERFSPDEAHSFYVNVMSFGFKYGLPLDADLVIDVRFLPNPYYIPDLKYQTGNDPAVQAYVMDNPLAQNFYQHLYSLIEVALPGYIKEGKSSLTIAIGCTGGQHRSVTIANRLAADLKNNQYPVHVHHRDVDKAN
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein LAF_0356.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: ACPS_LACAC
Sequence: MIKGVGIDSIEVERVKKIIDKGDLFAKKVLTPNEFAQYQKLEGKRKVEYLGGRFSLKESFSKAMGTGLGKSVGFQDIETLWDDLGHPVMTSTKFDGNIFPSITHDNHEIITFVVLEEK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLCA2_ECOLX
Sequence: MTDVQIPSPIVATRVAEADRLRFLPTYFGPSMLRMLRGEALVFGWMGRLCAAYHGGFWHFYTLSNGGFYMAPEHDGRLRIEVDGNGFAGELSADAAGIVATLFALNQLCAELAGTADADALIDRYHHLAAFASEHAEAAAIYRAID
What is the function of this protein?
Could be involved in overcoming restriction barriers during establishment after conjugative transfer.
What are the official names of this protein?
Antirestriction protein KlcA.
What is the protein family that this protein belongs to?
Belongs to the antirestriction protein family.
Protein: LEUC_SPHAL
Sequence: MTRPRTLYEKIWDAHVVERRGDGTCLIFIDRHLVHEVTSPQAFAGLRASGRTVRRPDLTLAVPDHNVPTTPRKDAAGNRLPIADPESAAQLAALEKNAPEFGIRYIDAIAPEQGIVHVVGPEQGFSLPGATIVCGDSHTACHGGIGALAFGIGTSEVEHVLATQTLLLQPAKTMEVRVEGDVGPGVSAKDIILHITGTIGAAGGTGHVIEYTGSAIRALSIEGRLTISNMAIEGGARAGLIAPDETTFAYLKGRPYAPKGADWDAAVAYWKSLTTDPGATYDKVVVIDAADIAPSVTWGTSPEDVVPITGTVPDPASFSDPSKRAAAAKSLAYMGLEPGTRMQDVPVENIFIGSCTNSRIEDLRAAAAVLKGRRKAPGVKWAIVVPGSGLVKAQAEAEGLDRIFIDAGLEWREPGCSACLAMNPDKVPAGERCASTSNRNFVGRQGPGARTHLVSPAMAAAAAVTGKLTDVRELMA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: LIPB_PELPD
Sequence: MILNDLGVVDYAAAFSLQERIADGVYRNATPETLLLLEHHPVYTIGRAGCEENILDHSIQAIRISRGGDVTFHGPGQLVGYPLINLRPRGCDLRHYLRFLEELLISVVADFGVSAFRVPGKTGVWTDQGKLAAIGVGVRHWVTMHGFAMNVNNDLSSFERINPCGIATCPIASLERLCGCPIAMDEVKSRVAGRFQGLLDEWLPAAGAL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_TRIV2
Sequence: MGTNYRRVLLKLSGEALMGNMGYGIDPEVVKEIAQEIAEVIATGVQIAIVVGGGNIFRGVKAASAGMDRATADYIGMIATVMNAMTLQDSLERIGVQTRVQTAIAMQELAEPYIRRRAIRHLEKGRVVIFGAGSGNPFFTTDTTAALRAAEIDAEVIFKATKVDGVYDADPEVYPNAKRYNSLTYAHVLAQDLRVMDSTAIALCKENNIPILVFDLTTRGNIRRAVLGESIGTLVGGSCEIS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_YERPY
Sequence: MSMQDPIADMLTRIRNGQAANKVAVTMPSSKLKVAIANVLKEEGFIEDFKIEGDTKPVLELALKYFQGKAVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RT10_PROWI
Sequence: MQQVQLKLKSFDPVYINQLISLLNDVLDTLEIQNSKEIFLPSKIKKITVIRSPHIHKKSRDQFQIKRYKRSMIISFTNIDILHAFLEICKDLHVVGVQIHISVKYHS
What are the official names of this protein?
Ribosomal protein S10, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LEPA_TRIL1
Sequence: MDISKIRNFSIIAHIDHGKSTLADRLLEYTGALTAREMQSQFLDKMDLERERGITIKAQTVRLNYTADDGNTYVLNLIDTPGHVDFTYEVSRSLAACEGGLLVVDASQGVEAQTLANVYLALDNDLEVFPVLNKIDLPAAEPERVKHEIEEIIGIDAHDAVLASAKEGIGTREILEEIVKKIPAPQGDVAAPLKALLFDSWYDQYQGVIILVRLFEGSLKKGDKIQLMSTNKAYEALKVGVFSPVMVEVPQLTAGEVGFVIAGIKDVADAKVGDTVTLLHRQCAEMLGGFKEVKPMVFSGLYPIDTAQYEQLRDALAKLKLNDSSFSFEPETSVALGFGFRCGFLGLLHMEIIQERLEREFGLDLITTAPTVVYRVHKMNGDVYSIQSANQMPELQSTEYLEEPFILAHIHVPNDYVGGVLALCEDKRGVQREIKYLTPTRVMIIYELPLNEIVLDFYDRLKSITKGYASLDYEHLEYRRSDLVRMNVLINGEVVDALSLILHRDKAYFRGRDLVSKMKELISRQMFEVAIQAAIGSKIIARETVKAMRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKNVGNVELPQEAFLAILKVDDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EAK4_CAEEL
Sequence: MGQCLAVHRRIMASQEFPNIPQPESQCHDAFIRYSPGRYERRAARSQVDYYLLPQAPRLMTEDLDKKEFQRLYDARCELVECPAGRRAMQLDVQIYADRYEATLNKILETSQELDKGLEDIFQAYTKDDPLADKVMNCRLTVDEMGRVYEHFFRESAWNLDSFVEYRKNLARDAYLLLADLKIAIQRLGMHFNPNFEDAQVKVDFQIMQAEQIIFHFKRTYRDALKHNPDSITEFVEDELEDPGTPL
What is the function of this protein?
Together with eak-6 and sdf-9, negatively regulates dauer larva formation downstream of the insulin-like receptor daf-2 and in parallel with age-1, pdk-1 and akt-1 (PubMed:16839187).
What are the official names of this protein?
Protein eak-4, Enhancer of akt-1 null 4.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: NU5M_ROUAM
Sequence: MNLRTSSTLLSLLILTVPIMASNFYPYTKKSYPIYVKTMVSYAFLVSLIPTMIFIQSGQETMISNWHWMTIQTLKLSLSFKLDYFSMILMPVALSVTWSIMEFSMWYMHSDPYINRFFKYLLLFLITMMLLVTANNLFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDVGFLVAMAWFLFNLNTWELQQIFTLNPTNTNLPLTGLLLAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFYPLTESNKTIQTMMLCLGAITTLFTAICALTQNDIKKIVAFSTSSQLGLMMVTVGINQPHLAFLHICTHAFFKAMLFLCSGSIIHSLNDEQDIRKMGGLYKSLPFTTTALITGSLALTGMPFLTGFYSKDLIIESINTSYTNAWALFITLIATSLTAVYSTRIIYFALLGQPRFPTLILINEDIPLLINPIKRLLVGSIFAGFFISNNITPTTIPQMTMPTYLKTTAMLVTLLGFIVALELNTATQNLKLTPPSNYLKFSNLLGYFPTIMHRLQPLTSLLTSQKVASMLLDLAWLENALPKSISIFQMKTSTLISSQKGQIKLYFLSFLITLTLSLIMLNFT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PCDA7_PANTR
Sequence: MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRVVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVERRVGERALSSYISVHAESGKVYVLQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSLIKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination.  Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-7, PCDH-alpha-7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CHBG_ECO7I
Sequence: MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAIDHAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRADRQMVFDLPVNLRTTQGFSSAFYGEEISESLFLQVLDDSSHRGERSLEVMCHPAFIDNTIRQSAYCFPRLTELDVLTSASLKYAIAERGYRLGSYLDV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG085_MONPV
Sequence: MIVLPNKVRIFINDRMKKDIYLGISNFGFENDIDEILGIAHLLEHLLISFDSTNFLANASTSRSYMSFWCKSINSATESDAIRTLVSWFFSNGKLKDNFSLSSIRFHIKELENEYYFRNEVFHCMDILTFLSGGDLYNGGRIDMIDNLNIVRDMLVNRMQRISGSNIVIFVKRLGPGTLDFFKQTFGSLPSCPEIIPSSIPVSTNGKIVMTPAPFYTVMVRINPTLDNILGILYLYETYHLIDYETIGNQLYLTVSFIDETEYESFLRGEAILQISQCQSINMNYSDDYMMNIYLNFPWLSHDLYDYITRINDDSKSILISLTNEIYTSIINRDIIVIYPNFSKAMCNTRDTQQHQIVVLDATNDGLIKKPYRSIPLMKRLTSNEIFIRYGDASLMDMITLSLSKQDISLKRNAEGIRVKHSFSADDIQAIMESDSFLKYSRSKPAAMYQYIFLSFFASGNSIDDILTNRDSTLEFSKRTKSKILFGRNTRYDITAKSSFVCGIVRGKSLDKTSLVEMMWDLKKKGLIYSMEFTNLLSKNTFYLFTFTIYTDEVYDYLNNNKLFSAKCLVVSTKGDVENFSSLKKDVVIRF
What is the function of this protein?
Probably involved in maturation of some viral proteins by processing them preferentially at Ala-Gly-|-Ser/Thr/Lys motifs.  Does not seem to be responsible for the cleavage of major core proteins.
What are the official names of this protein?
Metalloendopeptidase OPG085, Metalloendopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M44 family.
Protein: APEB_MYCBO
Sequence: MAATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQVPFRIVGAHTDSPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRDGTGVSHRLVRIDDPILRVPQLAIHLAEDRKSLTLDPQRHINAVWGVGERVESFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPRLDNQASCYAGMEALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYPDRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSAALQAFLSAELSEA
What are the official names of this protein?
Probable M18 family aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.