PharMolix/UniProtQA huggingface dataset:
Protein: ARGD_SALTY
Sequence: MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNVFTNEPALRLGRKLIDATFAERVLFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDEHQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQHLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADIHEGMQRFAQAVGKVVA
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Acetylornithine/succinyldiaminopimelate aminotransferase, ACOAT, DapATase, Succinyldiaminopimelate transferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_MERAN
Sequence: MSWQTYVDDHLMCDIDGQGQHLAAASIVGHDGSIWAQSASFPQLKPEEITGIMKDFDEPGHLAPTGLYIAGTKYMVIQGESGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLIEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Pollen allergen Mer a 1.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YMD2_CAEEL
Sequence: MPGTQTCIQNSRWTVVNLKNAFQAEGPWEFVLGNNSRSYLNLKRTYLVYTFNITDQNGAIVNIPNPITKDSLVYAPINNIAHSIVKNFSLHINSQLAYHNSSNYAYKAYFENALMYGKEIKNSTLTAAGYFHEDEIGTPTSKGFLNRCGTGTTQVAANISLDLMNQPRVLLNSCNVKLTAYPNNSEFLIEAYNHGQQKFKFNVTDVYALVNEFDLTDGLSNELEAAIIEHKMIQYPMISSQVRSFYIDGGRFDAPANTLFTSKMPRRLFLGLVSSEAYNGSFGTTPFNFKPYGVTDVHIDYCGQTIPGRPMNLDFENNKFVEAYVQLQETLGHTRNNFSCNSIDIGMFRSKGYTIFGFELSPVAQDNNLFELVRQTNVSVRLNFKKETPPGGLYCVVYAEFDQIFSLDFMRNPIVDSIV
What are the official names of this protein?
Uncharacterized protein F54H12.2.
Protein: LYS9_YEAST
Sequence: MGKNVLLLGSGFVAQPVIDTLAANDDINVTVACRTLANAQALAKPSGSKAISLDVTDDSALDKVLADNDVVISLIPYTFHPNVVKSAIRTKTDVVTSSYISPALRELEPEIVKAGITVMNEIGLDPGIDHLYAVKTIDEVHRAGGKLKSFLSYCGGLPAPEDSDNPLGYKFSWSSRGVLLALRNSAKYWKDGKIETVSSEDLMATAKPYFIYPGYAFVCYPNRDSTLFKDLYHIPEAETVIRGTLRYQGFPEFVKALVDMGMLKDDANEIFSKPIAWNEALKQYLGAKSTSKEDLIASIDSKATWKDDEDRERILSGFAWLGLFSDAKITPRGNALDTLCARLEELMQYEDNERDMVVLQHKFGIEWADGTTETRTSTLVDYGKVGGYSSMAATVGYPVAIATKFVLDGTIKGPGLLAPYSPEINDPIMKELKDKYGIYLKEKTVA
What are the official names of this protein?
Saccharopine dehydrogenase [NADP(+), L-glutamate-forming], Saccharopine reductase.
What is the protein family that this protein belongs to?
Belongs to the saccharopine dehydrogenase family.
Protein: NLTP_AMACA
Sequence: AVTCTVVTKALGPCMTYLKGTGATPPPANCCAGVRSLKAAAQTVADRRMACNCMKSAAQKTKSLNYKVAARLASQCGVRMSYSVSPNVNCNSVQ
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).
What are the official names of this protein?
Non-specific lipid-transfer protein, LTP, Phospholipid transfer protein, PLTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: OTU6B_CHICK
Sequence: MEGSEDEEAEAGGPLQQLVKRQRREKRELQAKIQGMKNAVPKNDKKRRKQLAEEVAKLEAELEQKHKEELKQLKEAMPEQNKIDSIADGVANFELEGREQQIQHPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHLESQKLASLLAARHLEIKQIPSDGHCMYRAIEDQLKDHHNSWTVATLRNQTAKYIHSHFDDFLPFLTNPNTGDMYSKEEFEKYCDDIANTAAWGGQLELRALSHILQTPIEVVQMDSPSIIVGEEYSGKPIILVYMRHAYGLGEHYNSVKLLTDATTENGS
What is the function of this protein?
Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of different cellular processes.
What are the official names of this protein?
Deubiquitinase OTUD6B.
Protein: GUAA_NITSB
Sequence: MQEVPIVILDFGSQYTQLIARRLREVGVYCEIYPFFEPIENIRAKKPQGIILSGGPASVYEPDAPRVDKAIYELGIPVLGICYGMQLITVDFGGQVVRALEHEYGKAKLYFDPIHGKVCPLFEGTKDGQIVWMSHGDKVTELPAGFIRIAHTDNSPYAAIANEEKQIYALQFHPEVSHSQEGQKILENFARKICGITSKWDMGHFAKEQIEKIRQRVGEDKVLCALSGGVDSSVVTALLYEAIGDKLIPVFVDNGLLREGEREKVEYVFKNMLKVPLIVVDAKERFLNALQGITDPEQKRKIIGHTFIEVFEEEAKKHTDVKYLAQGTLYPDVIESVSVKGPSETIKSHHNVGGLPDWMKFELIEPLRELFKDEVRKLGLELGLPREMVYRHPFPGPGLAIRILGEVNEEALDLVRKADTILLEEIKAHGLYEKLWQSFAVLLNVKSVGVMGDKRTYENTVALRIVESSDGMTATFAHIPHDLLELISNRIINEVDGINRVVYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ZNUC_RHIEC
Sequence: MLSPANAKNQRLVSLEDVGVLRGGRWLVRGVEFSVSRGEIVTLIGPNGSGKSTSAKAAIGVLKPDEGRVERLSGLKVGYVPQKLSIDWTLPLTVRRLMTLTGPLPERDMQAALEAAGIAHMIGAEVQHLSGGEFQRALMARAIARKPDLLVLDEPVQGVDFSGEIALYHLIKSIRNASGCGILLISHDLHVVMAETDTVICLNGHVCCRGTPEAVSRSPEYVRLFGSRAAQTLAVYSHHHDHTHLPDGRVLHADGSVTDHCHPEDGHHAHDSQEHAHGQDHVHAHEHSHDDHHGHDHAHEHAHSRSGEGRHA
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYL_ACIBY
Sequence: MTISHIDPEYQANTIEPSVQQDWENRKVFKVADTVEGKHRYILSMFPYPSGKLHMGHVRNYTIGDVISRFYRLKGETVLQPMGWDAFGLPAENAAIAHKVAPAKWTFENIAYMRDQLKKLGLSVDWDREFATCTPEYYHWEQWLFVQLYKKGLIYRKLSTVNWDPVDQTVLANEQVENGRGWRSGALVEKRDIPMYYFRITDYAQELLDDLDTLQDGWPQQVLTMQRNWIGRSTGMEITFPSANTEIYADGLTVYTTRADTLMGVTYVAVAAEHPLALKAAENNPELAAFIEECRMGSVAEADLATAEKKGMATGLFVKHPVTGEELPVWIANYVLMSYGSGAVMAVPAHDERDFEFANKFNLPIKQVIDAKGADDADYSATEWQEWYGSKEGKLVNSGEFDGLEFQAAFDAFLAKLEPQGLANSKVQFRLRDWGVSRQRYWGCPIPMINCDTCGQVTVPEDQLPVVLPTDVVPDGSGNPLNKMPEFYETKCPCCGGDARRETDTLDTFVESSWYYARYASPDFTGGMVKPEAAKNWLPVNQYIGGVEHAILHLLYARFFHKLMRDEGVVQGNEPFTNLLTQGMVLADTFYREAENGKKTWFNPADIELERDEKGRIISAKYSGDGQEVIIGGQEKMSKSKNNGIDPQAIIDQYGADTARVFMMFAAPPDQSLEWSDAGVEGANRFLKRVWRLVASFLEKGNSATAIDKANLSKDAQDLRRKTHETIQKVSDDIERRHAFNTAIAALMELLNASNKFEAKDDNDVAVEREAITTLLTLLAPFAPHLSQTLLAQFGTDLTEATFPEVDASALTRNTQTIVVQVNGKLRGKLEVSVDISKDELLAQAKALPEVQQFLTGPTKKEIVVPNKLVNLVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK_PHYMO
Sequence: AAGLFQFPRV
What is the function of this protein?
Myotropic peptide; increases the frequency of contraction of the heart and stimulates amplitude and tonus of the foregut.
What are the official names of this protein?
Periviscerokinin.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOA_STRTD
Sequence: MIEFEKPIITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLSSLPGAAVTSIKIDGVLHEFDTVPGVREDVMQIILNIKGLAVKSYVEDEKTIELDVQGPAEVTAGDILTDSDIEIVNPDHYLFTIAEGASFQATMTVSTNRGYVPAEENKKDDAPVGTLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIVTNGTIIPEDALGLSARILIEHLNLFTDLTDVAKATDVMKETEKVNDEKLLDRTIEELDLSVRSYNCLKRAGINTVHDLTEKTEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL2_CAMJ8
Sequence: MAIKTYKPYTPSRRYITGLSSEDITAKPSVRSLLVKLPAHAGRNSYGRITSRHKEAGAKKLYRIIDFKRRKFGIEGKVEAIEYDPYRNCRIALIAYKDGEKRYILQPRGLSVGDIVAAAESGLDIKPGNAMKLKNIPVGTIVHNVELKPGKGGQMIRSAGAYAQLMGKEEKYVILRLASGEMRQVLAECMASIGEVGNEEWANVTIGKAGRNRHRGIRPQTRGSAMNPVDHPHGGGEGKKNSGRHPVTPWGKPTKGAKTRRKKASDKLIISRRKGK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SYY_MYCPN
Sequence: MTKDLLALLKERGLFVQANFEKELKQLLNQGSFAFYVGFDPTAPSLHIGNYVLLHVAQIFQAMGHIPHVLLGSGTALIGDPTGRMELRQMMSRETIAENTRNIKKQIRRFLGSNVVFCQNETWLKKLNYIEVIRELGPCFSVNKMLATDAFSARWERGLTLMELNYMVLQAYDFYYLNQKYGVQLQIGGSDQWANILAGADLIRRKTQKQVYGMTTNLLVKANGEKMGKSASGALWLDPQKTSPYDFYQYWINLDDASLQKVFLMLTKLDTKAIETLCNLKGAAIKEAKAKLAFELTDAIHGTKAALVAQAKSARIFAFQPDTETKTVRAGTRLVDVIVDLGLVVSRSEARRVIQQGGLTINQEKVTDVEMVLQASSQPLVIGKGKKRFVTVQVIANTK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYNB_ASPFC
Sequence: MVSFSSLVLAASTVAGVLATPGSEQYVELAKRQLTSSQTGTNNGYYYSFWTDGGGQVTYTNGNGGQYQVDWNNCGNFVAGKGWNPASEKAVTYSGSWQTSGNGYLSVYGWTTSPLVEFYIVESYGSYDPSTGATHLGTVESDGATYNLYKTTRTNAPSIQGTATFDQYWSVRTSHRQSGTVTTKNHFDAWRNAGLQLGNFDYMIVATEGYQSSGSATITVS
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase B, Xylanase B, 1,4-beta-D-xylan xylanohydrolase B, Endo-1,4-beta-xylanase G1, Xylanase G1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: VP6_RYSV
Sequence: MSSQQETNDKSNTQGHPETDPEGKTGTDTGNTEDSPPDTDNVPITDDAIMDDVMDEDVKEEDIDYSWIEDMRDEDVDAEWLFELIDECNGWPD
What are the official names of this protein?
Protein 6.
What are the subcellular locations of this protein?
Virion.
Protein: MUTL_CHLP8
Sequence: MPSIAKLPDIVANKISAGEVVQRPASVVKELLENSIDSGASAITVVIKEAGRQLVRIIDNGCGMDSDDALLSVERFATSKISDVDDLNALRTLGFRGEALASISSVSHFELKTRRQSEPVGIQLISNGGEIEGPQPAQCEPGTSISVRNLFFNVPARRKFLKSNATEFKHIHETVKAFVLAYPEIEWRLINDDHELFYFRTPDVRERLSHFYGEGFGESLIEVTEENDYMTIGGYLGKPGMMVRQKYDQYFYINRRLIQNRMLVQAVQQAYAELLEERQSPFALLFLGLDPSLVDVNVHPAKLEVKFEDEKSIRSMVYPVVKRAVRTADFSPEATVAPSPAPVGSHGIGLPESSSRKLAYSDFSGKSSTTGDLYRNYRQGAFDLSGASVPPPSIDPVESSFGSGSGEPYPSMVQESLLTPSADQPSAADEQNPVAPDKEPKIWQLHNKYIICQIKTGLMIIDQHVAHERVLYERAIDVMNEAVPNSQQLLFPQKIDLKPWQYEVYEEISEELYRLGFTIRPFGGLSVMIEGVPPDVRDGNEATILQDMIAEYQENASKLKLEKRDNLAKSYSCRNAIMTGQKLDVEQMRMLIDRLFATRMPYVCPHGRPVIIRLSLGELDRMFGRT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: HIS5_XANOR
Sequence: MTDVALIDAGGANLGSVRYALERLGVEARVVRDAAGLQGAQRVILPGVGAAPEVMSRLRAQGLVAPLRELQVPLIGICLGMQLLFEHSEEGDVECLGLLPGIVRHMTPALGIRVPHMGWNRLVPMRESALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAIVQNGLRCGAQFHPERSADTGARILHNFLEMSFP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_SALTY
Sequence: MQAYFDQLDRVRYEGPQSTNPLAFRHYNPDELVLGKRMEDHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALELAKRKADVAFEFFHKLNVPFYCFHDVDVSPEGASLKEYKNNFAQMVDVLAAKQEQSGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMNATHKLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKMGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRGDAQLGWDTDQFPISVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALSLKIAARMVEDGELDKRVAKRYAGWNGELGQQILKGQLSLGELAQYAEQHNLAPVHQSGHQELLENLVNRYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5582_PHOPR
Sequence: MGRKFEVRKLSMAKTAGAKIKVYSKYGKEIYVCAKNGSLDPDSNLSLKRLIEKAKKDQVPSHVIEKAIDKAKGGAGEEFATARYEWFGPRYCMVIVDCLTDNNNRTFMDVRQAFVKNHAKIGGPGTVGHMFEHQAVFQFAGDDEDMVLENLMMEDVDVSDIECEDGIITVYAPHTEFFKVKNALAATMPDVAFDVEEISFVPQTMTEISGDDVAAFEKFLDVLNDCDDVQNIYHNAEIAE
What are the official names of this protein?
Probable transcriptional regulatory protein PBPRB1582.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP4_BOMTE
Sequence: VVGGKPAKLGAWPWMVALGF
What are the official names of this protein?
Venom protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2256_MYCBO
Sequence: MLWILGPHTGPLLFDAVASLDTSPLAAARYHGDQDVAPGVLDFAVNVRHDRPPEWLVRQLAALLPELARYPSTDDVHRAQDAVAERHGRTRDEVLPLVGAAEGFALLHNLSPVRAAIVVPAFTEPAIALSAAGITAHHVVLKPPFVLDTAHVPDDADLVVVGNPTNPTSVLHLREQLLELRRPGRILVVDEAFADWVPGEPQSLADDSLPDVLVLRSLTKTWSLAGLRVGYALGSPDVLARLTVQRAHWPLGTLQLTAIAACCAPRAVAAAAADAVRLTALRAEMVAGLRSVGAEVVDGAAPFVLFNIADADGLRNYLQSKGIAVRRGDTFVGLDARYLRAAVRPEWPVLVAAIAEWAKRGGRR
What are the official names of this protein?
Uncharacterized aminotransferase Mb2256c.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10E_PYRHO
Sequence: MALRPAKIDRYVDKPAYTRREYIRGAPGPKITIFDMGNPAGDFEFEVALHTAEPVQIRQNALEAARQQVNRYLQKNVGRSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARLKRDQKILSIRVNRQHLKFAIEGARRAAMKFPCKCYYRIYDKEGNDVTTKILSQGL
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: YBEY_MESH7
Sequence: MKAKINFLNQSRIKFKYLKLFRKIFKLLVEKEQITGEISLDLMLITQRKAQKLAIKFKNINYIPDVLSFPSNLIIAKKNFRLHFLGEIFMTPAKIIKQANEYGHSEEREFSYLFVHSIYHLLGFDHQDEKTNKLMDEKVENILINLGINR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL87_ORYSJ
Sequence: MASPSSFCLLAVLLALVSWQAIASDPSPLQDFCVADKHSPVLVNGFACLDPKYVNADHFFKAAMLDTPRKTNKVGSNVTLINVMQIPGLNTLGISIARIDYAPLGENPPHTHPRATEILTVLEGTLYVGFVTSNPNNTLFSKVLNKGDVFVFPEGLIHFQFNPNPHQPAVALAALSSQNPGAITIANAVFGSKPPISDDILAKAFQVEKGTIDWLQAQFWENNHY
What is the function of this protein?
Plays role in broad-spectrum disease resistance.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 8-7, Germin-like protein 6, OsGER6.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: VPS8_MOUSE
Sequence: METEPDQEHLDQNPCARTVEEELSKSFNLEASLSKFSCLDLDKELEFRSDLIDDKEFDIPQVDTPPTLESILNETDDEDESFVLEDPTLLNVDTIDSHSYDTSSVASSDSGDRANLKRKKKLPDSFSLHGSVMRHSLLKGISAQIVSAADKVDAGLPTAIAVSSLIAVGTSHGLALIFDQNQALRLCLGSTSVGGQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELTFKRVMGVRTCESRCLFSGSKGEVCCIEPLHSKPELKDHPITQFSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVAVNNSVNPMLAFCRGDMVHFLLVKRDESGAIHVTKQKHLHLYYDLINFTWINSRTVVLLDSVEKLHVIDRQTQEELETMEISEVQLVYNSSHFKSLATGGNVSQALALVGEKACYQSISSYGGQIFYLGTKSVYVMMLRSWRERMDHLLKQDCLTEALALAWSFHEGKAKAVVGLSGDVSKRKAVVADRMVEILFHYADRALKKCPDQGKIQVMEQHFQDTVPVIVDYCLLLQRKDLLFGQMYDKLSENSVAKGVFLECLEPYILSDKLVGITPQVMKDLIVHFQDKKLLENVEALIVHMDITSLDIQQVVLMCWENRLYDAMVYVYNRGMNEFISPMEKLFKVIAPPLNAGKTLTDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQVFEFLIRLHSVEASSEEEVYPYVRTLLHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIRMAEKAEFYQICEFMYEREHQYDKIIDCYLHDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMNHMEELVSLKPCKAAELVATHFSEQIEVVIGQLQNQLLLFKFLRSLLDPREGVHVNQELLQIPPHITEQFIELLCQFSPDQVIQTLQVLECYRLEETIQITQKYQLHEVTAYLLEKKGDAHGAFLLLLERLQSRLQEMTRQDENTKEDILLKGVEDTMVETIALCQRNSQNLNQQQREALWFPLLEAMMTPQKLSSSAAAPHPHCEALKSLTMQVLNSMAAFIALPSILQRILQDPIYGKGKLGEIQGLILGMLDTFNYEQTLLETTASLLNQDLHWSLCNLRASVSRGLNPKQDYCSICLQQYKRRQEMADEIIVFSCGHLYHSFCLQSKECTLEVEGQTRWACHKCSSSNKAGKLSENPSENKKGRITSSQVKMSPSYHQSKGDPPARKANSEPVLDPQQMQAFDQLCRLYRGSSRLALLTELSQNRGGDSCRPFAGPQSGPAFNSVFQKENFQLQLAPPPVAED
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway.  Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.  The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations.  Functions predominantly in APPL1-containing endosomes (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 8 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS8 family.
Protein: FAU1_SULIL
Sequence: MKGRVRIRGIYATALTSIFSSLSYEIVQQSVEIAERFMREVNNLPADITIKDFEYDRGKIIVMGNGTIEEDLHDVFKYSFHWKSPIKLYSVIEADESCTYGNFKVEPCLEEGIVIKPPYDGKIVLSETKAVSKYAMVWRGKGVTTFSEHINNEGERLRLLTLSSPLNRKGYNVKWRSNAKYATLNELKEDLERLVLRYENREFRDQGEDFYLITLSLPDKLHLDEVRKSIVNTVKYHHMLKLSYNREVDSLEKDKEGSPVKLLEALISDFMKIEHIKADGKAIYLRGGKVIEKEVNNDGYRITLRREINGNGVLDGIGKRIENGDYDIVEYNSDKWYQIHRYYSGIDNSLKGIYINISTPPELLKGKIRYLDLEIDIAIRDSEIIVLDEDELNKKSIYMHSSLVNKAKEVANYLIDCIQQNKLI
What is the function of this protein?
Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs.  Binds to RNA in loop regions with AU-rich sequences.
What are the official names of this protein?
Probable ribonuclease FAU-1, RNA-binding protein FAU-1.
What is the protein family that this protein belongs to?
Belongs to the FAU-1 family.
Protein: MDM10_CANTT
Sequence: MYTYMEYLQKCFYKSTNWNEDNIFSNITATSQAILEFPIPNGFKIDSSSKTTDYSASSFTLSNNHQINGSLAYLYSSVPLKNTMGTKDVSLQDAIAGFRIIEPMVRLQPKFNNKAPHSKSSLLYGRMYFPGSALEAMIIKRISENTQLLIKCVNNPHLSKNGTMIVYLQNNTAKYSREFIYSTNESLIGLRCLYNLGTPTSSSTVSSFNPRTIPKFDNSVVSIGTELWFATRSMSPGLSGALRYSTRSTSTGKPLTMTLAINPILGHISSTYTVKTSVASTFCSRYDFNVFSYASNLSLGFELYSYANKKRSDFYNHEIYSSSEENKYLKQHPELQKHHRVPIRAYKHHDNRTIINPIHNLDNVYHINPTLLSTTSGSGHTSETVTTAFQNLVNESDFSSVLKFSTSLNDKVVKILWEGRLRDFLVSTGVKLSLNPVTNTPEFNKLGISFSYAL
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: PRIO_CERNE
Sequence: MLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWHKPSKPKTSMKHMAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYEKESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: FOLD_MYCFO
Sequence: MAPVGSIVLDGKATRDEIFVDLKQRVAKLTEAGRTPGLGTVLVGDDPGSQAYVRGKHADCAKVGINSIRRDLPADITQAQLDETIDELNANPDCTGYIVQLPLPKHLDENAALERIDPAKDADGLHPTNLGRLVLGKDAPLPCTPRGIVHLLRRFDVPIAGAHVVVIGRGVTVGRPMGLLLTRRSENATVTLCHTGTRDLPALTRQADIIIAAVGVPHMVTADMVKPGAAVVDVGVSRVDGKLTGDVAPDVWEVAGHVSPNPGGVGPLTRAFLLTNVVELEESKLA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.