PharMolix/UniProtQA huggingface dataset:
Protein: TRIM2_AILME
Sequence: MASEATHIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNVEESSILETVTAVAAGKPLSCPNHDGNVMDFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLEGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYITAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIVTDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ
What is the function of this protein?
UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11.  Plays a neuroprotective function.  May play a role in neuronal rapid ischemic tolerance.  Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity.
What are the official names of this protein?
Tripartite motif-containing protein 2, E3 ubiquitin-protein ligase TRIM2, RING-type E3 ubiquitin transferase TRIM2.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3395_BACP2
Sequence: MANEFRVCDDCDATNLKTLLPRLKSVDPDAKIEIGCQSYCGPGRKKAFAFVNNRPLSAPTEDELLEKVQKKVK
What are the official names of this protein?
UPF0741 protein BPUM_3395.
What is the protein family that this protein belongs to?
Belongs to the UPF0741 family.
Protein: PPK5_BANRO
Sequence: SGETSGEGNGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, BanRo-Capa-PK, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_ECO55
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_SALPA
Sequence: MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEANAHPHVSEHIVVVHNGIIENHEPLREALKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDTRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDNTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIELLAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDGT_SALCH
Sequence: MTVQDYLLKFRKISSLESLEKLFDHLNYTLTDDMDIVNMYRAADHRRAELVSGGRLFDVGQVPQSVWRYVQ
What is the function of this protein?
Binds to H-NS and modified the range of genes it silences; H-NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer.  Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity).  The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity).
What are the official names of this protein?
Transcription modulator YdgT, H-NS/StpA-binding protein 2, OriC-binding nucleoid-associated protein.
What is the protein family that this protein belongs to?
Belongs to the Hha/YmoA/Cnu family.
Protein: ENO_BORA1
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGAMGRAAVPSGASTGTREAIELRDGDKNRYFGKGVLRAVENLNTEISEALMGLDAQEQTFVDRTLIELDGTDSKERLGANAMLAASMAVARAAADESGLSLYRYFGGSGPMSMPVPMMNVINGGAHANNTLDLQELMILPVGAASFREALRWGAEVFHVLKKLIHAQGMSTAVGDEGGFAPNLANHEAAIQLILKAITEAGYEPGTQIALGLDCASSEFYRDGKYTLAGEGGVSLSSQEFANLLATWCDKYPIISIEDGMAENDWDGWKLLTDQLGKKVQLVGDDLFVTNTRILREGIQKGVANSILIKINQIGTLTETFAAIEMAKRAGYTAVVSHRSGETEDSTIADIAVATNAMQIKTGSLSRSDRMAKYNQLLRIEEELAEVASYPGIEAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: OTRF1_STAAM
Sequence: MNKTKGFTKYKKMRYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSDNIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYVIDSIGSLSFIVLILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWNKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
What are the official names of this protein?
Putative O-acetyltransferase SAV0974.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPIA_NEOCA
Sequence: MKLLFFFLVLAVSAAVAENAGVQKAFMDIEIDGESAGRIVLELRGDVVPKTVKNFIGLFDKYKGSTFHRVIADFMIQGGDFENHNGTGGHSIYGPRFEDENFTLKHDRGVISMANAGPNTNGSQFFITTVKTEWLDGRHVVFGKITNDSWPTVQAIEALGSSGGRPSKIAKITDIGLL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Up-regulates interferon gamma production by bovine T-cells.  Stimulates high levels of IFN-gamma production by peripheral blood mononuclear cells and T-cells.  The IFN-gamma-inducing effect is blocked by cyclosporin A (CsA).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin, NcCyP, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
Protein: CYSD_SHEFN
Sequence: MAGRSLSHLQQLEAESIQIIREVAAEFGNPVMMYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTGWKFKEMIAFRDAQAKAFGFELLTHTNQEGVEQGVGPFTHGSAKHTDIMKTQGLKQALNKYGFDAAFGGARRDEEKSRAKERVYSFRDKHHRWDPKNQRPELWRTYNGAVNKGESIRVFPLSNWTELDIWQYIYQENIEIVPLYFAAPRAVVNKGGQLIMKDDDRMPLEEGDVESVERVRFRTLGCYPLTAAMPSEADTLEKIIEEMLLTRSSERQGRLIDSDQSASMEQKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: ACEA_RHOFA
Sequence: MSTTGTPKTTAEIQQDWDTNPRWKGVTRNFTAQQVSDLQGTVVEEATLARRGSEILWDLVNNEDYINSLGALTGNQAVQQIRAGLQAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPSVVRRINNALLRADEIAKIEGDTSVKNWVAPIVADAEAGFGGALNAYELQKAMIVAGAAGVHWEDQLASEKKCGHLGGKVLIPTQQHIRTLTSARLASDVADVPSVIIARTDAEAATLITSDVDERDREFLDGTRTAEGFFGVKNGIEPCIARAKAYAPYADLIWMETGVPDLEVAKKFSESVRSEFPDQLLAYNWSPSFNWKAHLDDATIAKFQKELGAMGFKFQFITLAGFHSLNYGMFDLAHGYAREGMTAFVDLQEREFKAAEERGFTAIKHQREVGAGYFDRIATTVDPNTSTAALKGSTEEGQFH
What is the function of this protein?
Involved in the metabolic adaptation in response to environmental changes.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: PCP_STRP7
Sequence: MKILVTGFNPFGSEKINPALEAVKLLPSEINGAEVRWVEIPTVFYKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPIRIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMRAGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R4RL1_MOUSE
Sequence: MLRKGCCVELLLLLLAGELPLGGGCPRDCVCYPAPMTVSCQAHNFAAIPEGIPEDSERIFLQNNRITFLQQGHFSPAMVTLWIYSNNITFIAPNTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPAGIFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGQGIFRGLVNLDRLLLHENQLQWVHHKAFHDLHRLTTLFLFNNSLTELQGDCLAPLVALEFLRLNGNAWDCGCRARSLWEWLRRFRGSSSAVPCATPELRQGQDLKLLRVEDFRNCTGPVSPHQIKSHTLTTSDRAARKEHHPSHGASRDKGHPHGHPPGSRSGYKKAGKNCTSHRNRNQISKVSSGKELTELQDYAPDYQHKFSFDIMPTARPKRKGKCARRTPIRAPSGVQQASSGTALGAPLLAWILGLAVTLR
What is the function of this protein?
Cell surface receptor that plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system (PubMed:22406547, PubMed:27339102).  Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum (PubMed:27339102).  Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (PubMed:26335717).  Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans (PubMed:22406547).  Binds heparin (PubMed:22406547).  Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200).  Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200).
What are the official names of this protein?
Reticulon-4 receptor-like 1, Nogo receptor-like 2, Nogo-66 receptor homolog 2, Nogo-66 receptor-related protein 3, NgR3.
What is the protein family that this protein belongs to?
Belongs to the Nogo receptor family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Perikaryon. Cell projection. Note=Localized to the surface of neurons, including axons.
Protein: ADH6_YEAST
Sequence: MSYPEKFEGIAIQSHEDWKNPKKTKYDPKPFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKVVKLGPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDGYVSQGGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNGCGPGKKVGIVGLGGIGSMGTLISKAMGAETYVISRSSRKREDAMKMGADHYIATLEEGDWGEKYFDTFDLIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPYGLKAVSISYSALGSIKELNQLLKLVSEKDIKIWVETLPVGEAGVHEAFERMEKGDVRYRFTLVGYDKEFSD
What is the function of this protein?
NADP-dependent alcohol dehydrogenase with a broad substrate specificity.
What are the official names of this protein?
NADP-dependent alcohol dehydrogenase 6, NADP-dependent alcohol dehydrogenase VI, ScADHVI.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: PB27A_ARATH
Sequence: MASASATATLLKPNLPPHKPTIIASSVSPPLPPPRRNHLLRRDFLSLAATSTLLTQSIQFLAPAPVSAAEDEEYIKDTSAVISKVRSTLSMQKTDPNVADAVAELREASNSWVAKYRKEKALLGKASFRDIYSALNAVSGHYVSFGPTAPIPAKRKARILEEMETAEKALTRGR
What is the function of this protein?
Probably involved in repair of photodamaged photosystem II (PSII).
What are the official names of this protein?
Photosystem II repair protein PSB27-H1, chloroplastic, Psb27-H1, Thylakoid lumenal protein PSB27-H1.
What is the protein family that this protein belongs to?
Belongs to the Psb27 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with PSII on the lumenal side of the thylakoid membrane.
Protein: PEPE_SALSV
Sequence: MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQTWDEYTDKTAEVLAPLGINVTGIHRVADPLAAIEKAEIIIVGGGNTFQLLKESRERGLLAPMADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALDLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGEEAVALEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLG2_MYCVP
Sequence: MSELRVAVLGVGVMGADHVARITSRISGARVSVVNDYVTEKAEQIASEVDGCRAVVDPLDAIADPEVDAVVLATPGSTHEKQLLACLDHRKPVMCEKPLTTDVFTSLEIARREAELECPLIQVGFMRRFDDEYMRLKALLDGGELGQPLVMHCVHRNPGVPSYFDSSLIVKDSLVHEVDVTRYLFGEEIASVQIVRPVSNPAAPEGVIDPQIAILRTVSGRHVDVELFVTTGVAYEVRTEVVGERGSAMIGLDVGLIRKSAPGTWGGLIAPGFRERFGRAYDTEIQRWVDAVRAGTNIDGPTAWDGYAAAAVCAAGVESLESGLPVPVHLAERPDRSTIRPR
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase 2, Myo-inositol 2-dehydrogenase 2, MI 2-dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: HIS7_HALMA
Sequence: MTDRTAAVTRTTAETDIEVTLDVDGDGDSTIDTGIGFFDHMLDSFSTHGLFDLTVQCDGDLDIDDHHTVEDVAITLGEAFTEALDDKRGIRRFADRKVPLDEAVASVVVDISGRPYFEFDGEFSQASVGGMTSHMAKHFCRSLSMNAGLTLHCGVDGENAHHEIEALFKSLARSLDDATRIDERRSDVASTKGEL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPER4_ARATH
Sequence: MCSKTSSVSYGNREDDDNYSSLCPKKQKHNNGGKKRVPRRGPGVAELEKIRLGEQHISTAAPFTLHHPPSLEKSPTITDRTGLVYPFSSYFSAGSFPSDLIPPAPVFQRKHDSSLHYLPPMNLPKQGSGGFYQFIEPPSSQTSSLDNVTKFLDEEKISSAKRPWHFMADTAKCSVGPSTTISRDAKQTRSLDLRLKNHVQDSGTTIRNPITIDSPSSASPPTTIFANPSLGFPRFLQKEEDDHEIIQRKSGTNFPLNKKPFYSFLPANDQIIRDQDRSFSLRTERYDTVPDHGIDLRLKL
What is the function of this protein?
Adapter-like transcriptional repressor recruiting TPL/TPR coepressors to inhibit TCP transcription factors (By similarity).  May be involved in leaf development.
What are the official names of this protein?
Protein SPEAR4, SPL-like, EAR-containing protein 4, TCP interactor containing EAR motif protein 3.
Protein: LEPA_CUPNH
Sequence: MDHIRNFSIIAHIDHGKSTLADRIIQLCGGLSDREMEAQVLDSMDIEKERGITIKAQTAALSYKARDGKVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTAIELGVEVVPVLNKIDLPQADPDNAIQEIEDVIGIDAQDATPCSAKTGQGVQDVIEALIAKVPPPEGDADAPLQALIIDSWFDNYVGVVMLVRVVNGTLRPKDKVLLMANGSQHLVEQVGVFTPKSIPRDALTAGQVGFVIAGIKELKAAKVGDTITTMQRKAEAPLPGFKEVKPQVFAGLYPVEANQYEALRESLEKLRLNDASLMFEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDMDLITTAPTVVYQVEMRDGTVITVENPAKMPDPSKIEAILEPIVTVNLYMPQEYVGSVITLCTQKRGSQINMSYHGKQVQLTYEIPMAEIVMDFFDRLKSVSRGYASMDYEFKEYRPSDVVKVDILINSDKVDALSVIVHRSNSQYRGREVAAKMREIIPRQMYDVAIQAAIGANIIARENVKALRKNVLAKCYGGDITRKKKLLEKQKAGKKRMKQVGTVEIPQEAFLAILQVDDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSMA_ECOK1
Sequence: MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAAKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_GEOKA
Sequence: MKERLYELKRQALEQIGQARDLKALNDVRVAYLGKKGPITEVLRGMGALPPEERPKIGALANEVREAIQQALEAKQAKLEQEEVERKLAAEAIDVTLPGRPVSLGNPHPLTRVIEEIEDLFIGMGYTVAEGPEVETDYYNFEALNLPKGHPARDMQDSFYITEEILLRTHTSPMQARTMEKHRGRGPVKIICPGKVYRRDTDDATHSHQFTQIEGLVVDRNIRMSDLKGTLREFARKLFGEGRDIRFRPSFFPFTEPSVEVDVSCFRCEGRGCGVCKGTGWIEILGAGMVHPNVLEMAGFDSKTYTGFAFGMGPERIAMLKYGIDDIRHFYQNDLRFLRQFLRV
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_ALKCK
Sequence: MKQVKELIGKRVLVLGMAKSGVASALLLARIGAEVVINDSKSRADQPQAGELEAAGIQVVCGGHPLTVLDGCSLLVKNPGIPYTNIVVKEAEARGIPIWTEIELAYLISEAEMVAITGSNGKTTTTTLVKEMLEHSGRKPLIAGNIGTVASEVAQKAKAEHVIVLEVSSFQLMGTNAFQPKVAVWLNIFDAHLDYHGTREDYIAAKARIAANMGPADYLVYNADDPTVVQAIARIGATLVPFSRINVVEDGAYVKDGTIFFKDEPILALADAVLPGAHNVENMLAATAAARLAGATVEQIRHVLSHFPGVKHRLQYVGSWEGRQFYNDSKATNILATKAALSGFAKPVVLIAGGLDRGNDFDELLASLKYVKAVVAYGETKSKLLALAAKANVQAVTAERVQDATEKAVALSQPGDVVLLSPACASWDQYRSFEERGDEFLDYVNTIIKPS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_BURCH
Sequence: MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLRFADVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPEFADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVLYAMKHDITPLGTMAHEYLQACQALGPRLRDSQIYGFEMWAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRCDPRTKVLVFSDALDIPKVMQLYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVDEDASK
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: MOT13_RAT
Sequence: MVHRTEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTLACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLRPLSLTEDTAVGGPWAQITSLLCHGPFLRYTVALTLINTGYFIPYVHLVAHLQDLGWDPLPAAFLLSVAAISDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQASTTLVVLAVAYGFTSGALTPVAFSVIPELVGTGRIYCGLGLVQMIESVGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLITLPHFFSCISLSTSRPQDLVIEAPDTKIPLPKEEGLGEN
What is the function of this protein?
Proton-linked monocarboxylate transporter.  May catalyze the transport of monocarboxylates across the plasma membrane.
What are the official names of this protein?
Monocarboxylate transporter 13, MCT 13, Solute carrier family 16 member 13.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: Y2477_GEOSW
Sequence: MGREFLGLFEEWADSYDQSVEGYDEEYREVFANYEDILNTVASKAGSVVLEFGVGTGNLTKKLLEQGKTVYGIEPSEPMRKKAREKLGDKVLIVDGDFLQFPLPPKPIDTIVSTYAFHHLTDEEKGEAIAKYSQLLKKGDKIVFADTAFRDRQAFQRAIEEARERGFHHLADDLGREYYTTLDVLTKLFKENGFTVTFTQKNAFVWVMEAVKQ
What is the function of this protein?
Could be a S-adenosyl-L-methionine-dependent methyltransferase.
What are the official names of this protein?
Uncharacterized methyltransferase GWCH70_2477.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. YrrT family.
Protein: SAHH_PROMM
Sequence: MVAVPTSTASLQALPQYVVADIDLADFGRKELSIAETEMPGLIALRIKYGSEKPLKGARIAGSLHMTIQTGVLIETLVALGADVRWASCNIFSTQDHAAAAIAASGVPVFATKGETLDEYWAYTHRILEWGDGGTPNMILDDGGDATGLVMLGSKAESDSSVLDNPGNEEETALFASIRTKLAEDSSFYSRIKSSIQGVTEETTTGVARLYQMQKSGELPFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMVAGKVALVMGYGDVGKGSAQSLRGLGATVMIAEIDPICALQAAMEGYRVVRLDEVVQDVDIFVTSTGNFQVIRHEHLIRMKDEAIVCNIGHFDNEIDVASLKDYPWENIKPQVDHITLPSGNKIILLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQIELFSKGDQYADQVYVLPKHLDEMVARLHLEKIGARLTELTKQQADYISVPVEGPYKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.