PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_SYNY3
Sequence: MAIILAIETSCDETAVAIVNNRNVCSNVVSSQIQTHQIFGGVVPEVASRQHLLLINTCLDQALQASGLGWPEIEAIAVTVAPGLAGALMVGVTAAKTLAMVHQKPFLGVHHLEGHIYASYLSQPDLQPPFLCLLVSGGHTSLIHVKGCGDYRQLGTTRDDAAGEAFDKVARLLDLGYPGGPAIDRAAKQGDPGTFKLPEGKISLPQGGYHPYDSSFSGLKTAMLRLTQELKQSSAPLPVDDLAASFQDTVARSLTKKTIQCVLDHGLTTITVGGGVAANSRLRYHLQTAAQEHQLQVFFPPLKFCTDNAAMIACAAADHFQNGDRSPLTLGVQSRLSVEQVSQLYERN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_SALPA
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDAKNVNADMATGEIEVLASSLTIINRADSLPLDANHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELVDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGAQLSRKQIDDYGNFVKIYGAKGLAYIKVNERAKGLDGINSPVAKFLTADIVEAILERTGAQDGDMIFFGADNKKVVADALGALRLKLGKDLSLTDEDKWAPLWVIDFPMFEDDGEGGLTAMHHPFTAPRDMTASELKTAPEEAVANAYDMVINGYEVGGGSVRIHNGEMQQTVFGILGINEQEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANQAALTELGIPVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F4ST_FLACH
Sequence: METTKTQFESMAEMIKKLPQHTCSSLKGRITLYKYQDFWGLQNNIEGAILAQQSFKARPDDVFLCSYPKSGTTWLKALAYAIVTREKFDEFTSPLLTNIPHNCIPYIEKDLKKIVENQNNSCFTPMATHMPYHVLPKSILALNCKMVYIYRNIKDVIVSFYHFGREITKLPLEDAPFEEAFDEFYHGISQFGPYWDHLLGYWKASLERPEVILFLKYEDVKKDPTSNVKRLAEFIGYPFTFEEEKEGVIESIIKLCSFENLSNLEVNKSGNSKGFLPIENRLYFRKAKDGDWKNYFTDEMTEKIDKLIDEKLSATGLVLK
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of quercetin 3-sulfate > kaempferol 3-sulfate > isorhamnetin 3-sulfate > patuletin 3-sulfate, but not tamarixetin 3-sulfate.  O-sulfation of position 4' of flavonol.  May play a role in auxin transport.
What are the official names of this protein?
Flavonol 4'-sulfotransferase, F4-ST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y182_STRP4
Sequence: MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYVLLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE
What are the official names of this protein?
UPF0473 protein SPG_0182.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: MENG_STAEQ
Sequence: MAENQAKKEQVHTVFQNISQKYDRLNNIISFEQHKVWRKHVMSTMNVQKGSKALDVCCGTADWTIALSEAVGSKGQVTGLDFSENMLEVGKQKTASLENIQLVHGDAMNLPFDDNSFDYVTIGFGLRNVPDYLSALKEMHRVLKPGGMVVCLETSQPTLPLFKQIYSLYFKFVMPIFGKMFAKSKEEYEWLQQSTFNFPDKQTLKGLFFEAGFNDIIVRSFTGGVAAMHLGYKENSSSKGD
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: YACG_SHEDO
Sequence: MSLVVQCPICQSSVPWTDDAKFKPFCSERCKLIDLGDWASEKHVIPVKSPFEAGLLDPDLLDDAGFEQDDFFKE
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: CILK1_RAT
Sequence: MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFIWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQIGHPLGISTQDSGKPQKDVQDKTGPPPYVKPAPPAQAPTKAHTLISSRPNQASQPHQHFVYPYKGEASRTEQLSHVQEGQPNPPFFPSLHNKNLPPKILAGLEQKSGDMKPKSRRRWGLISRSTKGSDDWADLADLDFSSSLTRIDVKNKKRQSDDPLCRFESVLDLKPSEPVGTGTSVSTQASSQRRDTPTLQSTAKQHYLKHSRYLPGINIRNGVLPNPGKDFLPSSSWSSSGLSGKSSGTVSVVSKITSVGSGSTSSTGLTGSYIPSFLKKEVGSVMQRVQLAPLAAPSPGYSSLKAVRPHPGRPFFHTQPRSTPGLIPRPPAVQPVHGRIDWSSKYPSRR
What is the function of this protein?
Required for ciliogenesis, particularly in neuronal and retinal progenitor cells (By similarity).  Phosphorylates KIF3A (By similarity).  Involved in the control of ciliary length (By similarity).  Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity).  May play a role in cardiac development (PubMed:8570168).  Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase ICK, Intestinal cell kinase, MAK-related kinase, MRK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium. Nucleus. Cytoplasm, cytoskeleton, cilium basal body. Note=Also found at the ciliary tip.
Protein: GNA11_BOVIN
Sequence: MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHRYVSAIKTLWNDPGIQECYDRRREYQLSDSAKYYLTDVDRIATSGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIVTYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  Acts as an activator of phospholipase C (By similarity).  Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs) (By similarity).  Together with GNAQ, required for heart development (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein subunit alpha-11, G alpha-11, G-protein subunit alpha-11, G-protein subunit GL2 alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cytoplasm.
Protein: RNC_AGRVS
Sequence: MKAPKALTAEEREKVEAVIGYHFIGKERLDKALTHSSARPAKGSDYERLEFLGDRVLGLCVAEHLFKVFRAATEGELSVRLNQLVSAETCAAVADEIQLHRYIRTGADVKKLTDKNMLNVRADVVESLIAAIYLDAGLEAARAFVLKFWAERASRQDAGRRDAKTELQEWAHAKFAVTPVYRVADRSGPDHDPSFTVTVEIGKLEPETGIDRSKRAAEQAAATRLLEREGVWTRSTASD
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEHQ_ECOLI
Sequence: MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHENDALIATFSDGVRTQLANGQALKEAQCSCGANGMCRHRVMLVLSYQRLCATTQSTEKEEEWDPAIWLEELATLPDATRKRAQALVAKGITIELFCAPGEIPSARLPMSDVRFYSRSSIRFARCDCIEGTLCEHVVLAVQAFVEAKAQQAEFNHLIWQMRSEHVTSSDDPFASEEGNACRQYVQQLSQTLWLGGISQPLIHYEAAFNRALQAAETCNWRWVSESLRQLRASVDAFHARASHYNAGECLHQLAALNSRLNCAQEMARRDSIGEVPPVPWRTVVGSGIAGEAKLDHLRLVSLGMRCWQDIEHYGLRIWFTDPDTGSILHLSRSWPRSEQENSPAATRRLFSFQAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVALREYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNVLTLSLPASASAPYAVERMAALLQQTDDPVCLVSGFVSFVEGQLTLEPRVMMTKTRAWALDAETTPVAPLPSASVLPVPSTAHQLLIRCQALLIQLLHNGWRYQEQSAIGQA
What are the official names of this protein?
Protein YehQ.
Protein: RNFA_YERP3
Sequence: MTEYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGLATTFVLTLASVCAWMVNSFILLPLGLIYLRTLAFILVIAVVVQFTELVVRKTSPTLYRLLGIFLPLITTNCAVLGVALLNVNQSHNFMQSAVYGFSAAAGFSLVMVLFAAIRERLAVADVPAPFRGSSIALITAGLMSLAFMGFTGLVKF
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS8_METPE
Sequence: MQPSIRSYLRTGPGYVYAAHSGTARETGRIACLASNENPFPPSEAAIAAGAAALATVNRYPDDRMTDLTEALKRLHGDHTFVVGNGMDGIIETVLRCFIGHGDRVVVSTPTFSFYGIAAAGQGAIVENIQRKEDFTVDIPAFTRACTGAKVAFLCTPNNPTGTVTTPAEVRKVLDGIGDCMLFLDNAYVDFARDDYRPLMGEYENLIIGRTMSKIFGLAGLRVGYAFIPAWLEPFYMKAATPFSGISSVSAAAAVAALADREHRERTLAHMLEWRERVRSAVRFPVLPSEANFLMIDVAPHTADDVVATLAGRGVLIRSCRSFPGLGDHYVRVSIGDAWENERFIEEINRI
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SYP_LACLM
Sequence: MKQSKMLIPTLREMPSDAQVISHALLMRAGYVRQVSAGIYAYLPLANRVLEKLKNIMREEFDEIGAVELLAPSLLTADLWRESGRYETYGEDLYKLKNRDSSDFILGPTHEETMTSLVRDEITSYKKLPLNVYQIATKFRDEKRPRYGLLRGREFLMKDGYSYHADQDSLDETYLDYKKAYEKIFERAGLNFKPIIADAGAMGGKDSQEFIAITDDRINLEKWLVLSKNITSIDEIPESVLSEIQEELGKWLVAGEDTIVYAEGGDYAANIEMATSQFEPNVAYTEELELEKVATPGAKTIDEVSDFLEIDEEQTVKTLVYHADDELIVILLNGNDQLNEVKLTNHLGASFIEAASEAEVEEKFGAHFGSLGPIGLENVRIIADRKVELIKNAVVGANVDGYHYKNANFGRDFEVEEFVDLRTVNEGEISPDGRGTLKFARGIEIGHIFKLGTRYTEAMNANILDANGRSIPMLMGCYGIGVSRLLSAILEQFARIYVEKTPREEFKFSWSINFPKELAPFDIHLVPVNVKDEAAMELTSELEEKLRGKGYQVLVDDRNERAGVKFADSDLIGLPVRVTIGKKAAEGIVEVKIRATGEVVEINKDELVNTIEILSK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_DICT6
Sequence: MEITEIKLKKRDKIGKQYAKKYRRSNLIPGVVYGAHLKENIHVLVEKKDLWNLIKKGHSKEQHILRLIIEDGENTITENAILQDIQIDPIKDDLLHVDFHAVSLEEVVDVYVPVVLVGESKGVKQGGILQHGVEEILIRALPLDVPPHIEVDITDLEIGDSITVGDLNLPENIKVLTPADEVIVNIIPPKGYTEEASTEESQTESQS
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ALG11_KLULA
Sequence: MKLADFVTYVFGSLLAGLVTLKVLSSFIPSLLVTLPAKVRLRVNNSLLKCSNNLNRIPVLDFGWKNSSVRRAFILASERPSDYTNKIYGDRVHIAYNDRIKRESFVNKLGFDSKRKLLGFFHPYCNAGGGGEKVLWKAVETSLNQDKNNICVIYTGDTDVNGSDILNSVRRRFEYDLDSDRIVFIFLQKRRLVESKSWPKFTLLGQAYGSIILSIEALTTLAPDYWIDTMGYPFAYPFVSLFARIPIVTYTHYPVISTDMLQKLKTMPGFHTNFKLIGKYVYWKIFMLAYKFSGLFVEIASTNSTWTYNHIKSIWSSTKNIHIIYPPCSTESLIEGCDKSDPVKRLNQAVVIAQFRPEKRHELILSSFSSFIDATTKKDLIPKIIFIGSTRNVEDREYVETLKKYAFEALKIPTHLVDFKTDCKYDDMKSILYSSWFGINAMWNEHFGIAVVEYMASGLIPLCHASAGPLYDIVVPWDSKKNEQSTDKANETGFFFIDETDPDFLAKDSSKYSSLRTLFAQVSKLNTVQRIDISNRAKMCSLSKFSDSEFERSWNEVLEELNLTHNRMFS
What is the function of this protein?
Required for N-linked oligosaccharide assembly.  Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).
What are the official names of this protein?
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Alpha-1,2-mannosyltransferase ALG11, Asparagine-linked glycosylation protein 11, Glycolipid 2-alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CDC68_HALSA
Sequence: MKTPFRDRVELFANKDVLKDHYEPEEIRERDEEIDQYANALQDVVDGWEPDNVFVYGKTGVGKTAVTRYMMDALEYEADDRDGVDSVTSVEVNCHHHPSSYQAAIALVNELRGDTDSDPLTTGLSTSDVLNALFDEIEAREGTVLIVLDEIDNLDDDDMLLYQLPRAKTNGNIEDSQVAVVGISNDYTFRNDLSPKVQDTLCEREIKFPPYDANELVTILDDRAERALSSGVLTGGVIPQCAALAARDRGSARQAIDLLRESVNVAIEDERETVTEDDVETAVRRVERGRIKDSIKDLTTHGQYVLLAVTQTAIADDTPVRAKELYEVYADIAAEYASDPLSQRSVHDHLNDLSMLGFLRQHDRNYGRGGGQFFEYELDVDATMVQEAIADADDATV
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 8.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: RL3_CHLPB
Sequence: MAAILGKKIGMTSIYNANREAEPCTVIQAGPCFVSQVKTTENDGYEAYQLSIGERKEAKVSKPLRGHFAKAGIAPGYKVVEFGKDDMGLDLEQGSAVSVEIFSAGDAVEVQGVSKGKGFAGVVKRHNFSGGQRTHGQSDRLRAPGSVGGASDPSRTFKGTKMGGRMGGKTVKVKGLEIVKVIPESNLLVIKGSVPGVKNSYVQIVSSKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YKBH_SCHPO
Sequence: MDRISAQKDIFKKVVNKENSSIFVSLGVFAVSVAILKSRLGNFLVPQL
What are the official names of this protein?
Uncharacterized protein SPAC823.17.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ILVD_SHEFN
Sequence: MPKLRSATSTEGRNMAGARALWRATGVKENDFGKPIIAIANSFTQFVPGHVHLKNMGSLVAGAIEEAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKTKLSDQIIKLDLVDAMIAGADSNVSDEDSKQIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHEDRRELFLEAGRRVMMLAERYYKHDDETALPRNIASFKSFENAMVLDVAMGGSSNTVLHLVAAAQEAEIDFTMADIDRISRLVPHLCKVAPSTPKYHMEDVHRAGGVMGILGELDRAGLIHNDVPHVAADNGGDLKSVLAKYDIKQTNDPDVIRFFSAGPAGIPTTKAFSQNCRWDSVDDDRENGCIRSREFAFSQEGGLAVLSGNVAVDGCIVKTAGVDESNLTFVGSARVYESQDDAVAGILGGEVVEGDVVVIRYEGPKGGPGMQEMLYPTTYLKSRGLGAKCALITDGRFSGGTSGLSIGHVSPEAASGGTIALIENGDQIAIDIPKRSIQLNVSEAELTQRRTAMDAKGPLGWKPVSRERYVSLALKAYALLATSADKGAVRDRTKLEG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TXH2A_ETHRU
Sequence: MKSFFVVFAIVFQATLVALSLAADADDGQCINTTAVVEYFNPFIQECCPNEEPPSRDCVTCGLKGAGLVVTEDGKEMFDFDKYRRKLRGRIIRNERLIYRSLRECCRRRLCEAEPTFTCFHDKVKEQCPGDRTTSLLRSPLKDLPLRSPSC
What are the official names of this protein?
U-scoloptoxin(17)-Er2a, U-SLPTX(17)-Er2a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENGB_ALKOO
Sequence: MKVISSEIVISAVAPKQYPENGLPEIALAGRSNVGKSSTVNTILKRRKLARVSASPGKTRTINFYIVNNEFHIVDLPGYGYAKVSKGEKETWGKMMETYLSSRKNLYEVILLVDIRHEPTADDKMMYDWIKHYGYGSIVIATKSDKISRGAYQKHFKMIREKLGMSPEDKIIPISSLKREGIDKLWHSIEEIFIANNLPITIEEAEEY
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: EXGA_ASPNC
Sequence: MFVESAKKALLALSLLAASAQAVPRVRRQGASSSFDYKSQIVRGVNLGGWLVTEPWITPSLYDSTGGGAVDEWTLCQILGKDEAQAKLSSHWSSFITQSDFDRMAQAGLNHVRIPIGYWAVAPIDGEPYVSGQIDYLDQAVTWARAAGLKVLVDLHGAPGSQNGFDNSGHRGPIQWQQGDTVNQTMTAFDALARRYAQSDTVTAIEAVNEPNIPGGVNEDGLKNYYYGALADVQRLNPSTTLFMSDGFQPVESWNGFMQGSNVVMDTHHYQVFDTGLLSMSIDDHVKTACSLATQHTMQSDKPVVVGEWTGALTDCAKYLNGVGNAARYDGTYMSTTKYGDCTGKSTGSVADFSADEKANTRRYIEAQLEAYEMKSGWLFWTWKTEGAPGWDMQDLLANQLFPTSPTDRQYPHQCS
What is the function of this protein?
Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall.  It could also function biosynthetically as a transglycosylase (By similarity).
What are the official names of this protein?
Probable glucan 1,3-beta-glucosidase A, Exo-1,3-beta-glucanase 1, Exo-1,3-beta-glucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCX12_TITOB
Sequence: MKGLILFICGFMMIGVILAKEGYPMDHEGCKFSCFIRPSGFCERYCKTHLSASTGYCAWPACYCYGVPANQKVWDYYNNKCGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin To12, T-beta* NaTx5.5.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_BRUA4
Sequence: MVDINQIPTRRPFHRRRKTCPFSGANAPKIDYKDIKLLQRYISERGKIVPSRITAVSQKKQRELAKAIKRARFLGLLPYVVK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RS16_ORYSJ
Sequence: MAAALTRPPPGTVQCFGRKKTAVAVSYCKPGRGLIKVNGVPIELIRPEMLRLKAFEPILLAGRSRFKDIDMRIRVRGGGKTSQIYAIRQAIAKALVAYYQKYVDEASKKEVKDIFARYDRTLLVADPRRCEPKKFGGRGARARFQKSYR
What are the official names of this protein?
40S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_ECO55
Sequence: MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQCEILR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: THII_PROMH
Sequence: MKFIIKLFPEITIKSQSVRIRFIKILTSNIRNVLSTLGDDITVVRHWDNIVVVSKDESKSEAVCDALTRIPGIHHFLQVEEHSYTDLHNIFEQTFAAFGHLVENKTFCVRAKRRGKHSFTSNEVERYVGGGFNQHVESAKVKLTRPDVTINLEIEDDKLILVNARYEGIGGFPIGTQEDVLSLISGGYDSGVSSYMLMRRGSRVHYCFFNLGGSAHEIGVKQVAHYLWNRFGRSHKVHFVAVDFEPVVAEILEKIDDGQMGVVLKRMMVRAASRVAERYGVQAIVTGEALGQVSSQTLTNLRLIDNATDTLILRPLITHDKENIINIARQIGTEDFARTMPEFCGVISKNPTVKAVKAKIEAEEEKFDFSILDSVVENAKNMDIRRIAEETVQQVTEVEMVSEFATNDVVLDIRSPEEQENSPLKLEGVDVKELPFYKLSTQFGDLDNSKTYLLYCERGMMSRLQALYLREQGFNNVKVYRKK
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDD_ECOSE
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.