PharMolix/UniProtQA huggingface dataset:
Protein: RLME_THEVO
Sequence: MTGDRRDEYYWKAKKEQLRSRAAFKLEFLLDRYRVVRKGDAVIEIGSSPGGWTQVLNSLARKIISIDLQEMEEIAGVRFIRCDIFKETIFDDIDRALREEGIEKVDDVVSDAMAKVSGIPSRDHAVSYQIGQRVMEIAVRYLRNGGNVLLKQFQGDMTNDFIAIWRKNFSSYKISKPPASRGSSSEIYIMFFGFKAP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_GEOMG
Sequence: MGDLAAIILAAGKGTRMKSDLVKVMHPLAGAPMVAWPVEAARQAGTSRMVLVVGHQADTIREHFAGTEQVAFALQEEQLGTGHAVASAAAALDGFTGRVLILCGDVPLIRPETLRGMIDAHGATGAALTVLTTRLENPFGYGRIIRGFDGRVIRIVEEKDATPEERGRREVNAGIYCAEAAFLFDAVTRIGNDNAQGEYYLTDIVTMANEQGLRCTAHPVADPVEVMGVNDRAQLAEAGRFARQRINRELMLDGVTIVDPAATYIDRGAVVGRDTTVHPGVHLSGETRIGEGCTIEQGAVIKGSTLGNGCVVEPGAVIRSCRLGSHVMVKAGSVMEDAIIHDHTAIGPMAHLRPGTELMAHVKIGNFVETKKITMGEGSKASHLTYLGDASIGNNVNVGCGTITCNYDGVRKHRTVIEDDVFVGSDVQFVAPVTVGRNSLIAAGTTVTRDVPPDSLAIARAPQVNKDGWKLKQRDQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADM_METB6
Sequence: MKRGFYVGRFQPYHNGHQAVLSELARTCDEIILGVGSAQLSHTLENPFTAGERVLMITRALTDLRCPYYVIPIEDVQRNALWAAHVRSMTPPFDTCYSSNPLVVRLFFEAGVDVQSPAMYERDRHSGTEIRRRMLAGEPWENLVPPAVVTVVREIDGVERLREIARAD
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_ECOL6
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I, NUO9.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GG1_ARATH
Sequence: MREETVVYEQEESVSHGGGKHRILAELARVEQEVAFLEKELKEVENTDIVSTVCEELLSVIEKGPDPLLPLTNGPLNLGWDRWFEGPNGGEGCRCLIL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.  Involved in the abscisic acid (ABA) and ethylene signaling pathways.  Regulates acropetal transport of auxin (IAA) in roots and hypocotyls, and thus modulates root architecture (e. g.  lateral root formation).  The heterotrimeric G-protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression; involved in resistance to fungal pathogens such as Alternaria brassicicola, Plectosphaerella cucumerina and Fusarium oxysporum.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit gamma 1, Ggamma-subunit 1, Heterotrimeric G protein gamma-subunit 1, AtAGG1.
What are the subcellular locations of this protein?
Cell membrane. Golgi apparatus membrane. Golgi apparatus, trans-Golgi network membrane. Cytoplasm. Note=Localized to the cell membrane when attached to beta subunit GB1 (Probable) (PubMed:17158913). Present in the cytoplasm when associated with NUDT7 (PubMed:22068106).
Protein: XYLS_PSEPU
Sequence: MDFCLLNEKSQIFVHAEPYAVSDYVNQYVGTHSIRLPKGGRPAGRLHHRIFGCLDLCRISYGGSVRVISPGLETCYHLQIILKGHCLWRGHGQEHYFAPGELLLLNPDDQADLTYSEDCEKFIVKLPSVVLDRACSDNNWHKPREGIRFAARHNLQQLDGFINLLGLVCDEAEHTKSMPRVQEHYAGIIASKLLEMLGSNVSREIFSKGNPSFERVVQFIEENLKRNISLERLAELAMMSPRSLYNLFEKHAGTTPKNYIRNRKLESIRACLNDPSANVRSITEIALDYGFLHLGRFAENYRSAFGELPSDTLRQCKKEVA
What is the function of this protein?
Regulatory protein of the TOL plasmid xyl operons.  XylS activates the xylXYZLTEGFJQKIH operon required for the degradation of toluene, m-xylene and p-xylene.
What are the official names of this protein?
XylDLEGF operon transcriptional activator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINP1_CHICK
Sequence: MAPRRAACLLPLLVAVASAGLGGYFGTKSRYEEVNPHLAEDPLSLGPHAAASRLPAACAPLQLRAVLRHGTRYPTAGQIRRLAELHGRLRRAAAPSCPAAAALAAWPMWYEESLDRLAPRGRRDMEHLARRLAARFPALFAARRRLALASSSKHRCLQSGAAFRRGLGPSLSLGADETEIEVNDALMRFFDHCDKFVAFVEDNDTAMYQVNAFKEGPEMRKVLEKVASALCLPASELNADLVQVAFLTCSYELAIKNVTSPWCSLFSEEDAKVLEYLNDLKQYWKRGYGYDINSRSSCILFQDIFQQLDKAVDESRSSKPISSPLIVQVGHAETLQPLLALMGYFKDAEPLQANNYIRQAHRKFRSGRIVPYAANLVFVLYHCEQKTSKEEYQVQMLLNEKPMLFHHSNETISTYADLKSYYKDILQNCHFEEVCELPKVNGTVADEL
What is the function of this protein?
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) (PubMed:9472008).  Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate (By similarity).  May play a role in bone development (endochondral ossification) (By similarity).  May play a role in the transition of chondrocytes from proliferation to hypertrophy (PubMed:8660956, PubMed:9472008).
What are the official names of this protein?
Multiple inositol polyphosphate phosphatase 1, 2,3-bisphosphoglycerate 3-phosphatase, 2,3-BPG phosphatase, Band 17, Histidine phosphatase of the endoplasmic reticulum 1, HiPER1.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family. MINPP1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: LIN7B_BOVIN
Sequence: MAALVEPLGLEREVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYS
What is the function of this protein?
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.  Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.  The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).  This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.  Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.  Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.  May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity).
What are the official names of this protein?
Protein lin-7 homolog B, Lin-7B.
What is the protein family that this protein belongs to?
Belongs to the lin-7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Mainly basolateral in renal epithelial cells.
Protein: EX7S_EDWI9
Sequence: MAKKAPAAPAFEQALSELEQIVVRLESGDLPLEEALSEFERGIRLARQGQQTLQQAEQRVKILLSDDQDAPLSPFNAEQE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBH_ORYNI
Sequence: MATQTVEDSSRPGPRQTRVGNLLKPLNSEYGKVAPGWGTTPFMGVAMALFAVFLSIILEIYNSSVLLDGILMN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATP6_PAPHA
Sequence: MNENLFTSFSAPTILGQPATIPIIMFPTLLIPTSKHLINNQLTTVQQNLIKLTLKQMMAPHNAKGQSWSLMLMSLITFITMTNLLGLLPHSFTPTTQLSMNLAMAIPLWAGTIITGLRFKTKNFLAHMLPQGTPTPLIPMLVMIETISLLIQPMALAVRLTANITAGHLLMHLIGNTMLTLSTINLSTTLLTSVLLMLLTILEIAVALIQAYVFTLLVNLYLHNNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UVRC_CLOAB
Sequence: MFDFEYQLKNLPDKPGVYIMKNSLGEVIYVGKAKILKNRVRQYFRNSKNHSEKVKAMVKNISEFEYIVTDSEIEALILECNLIKKYKPRYNILLKDDKHYPFIKVTMNEDFPRIIVTRNMVKDGSKYFGPYPDVSAVHETVDLMRRIFPIRTCKKYIKENGENIRPCLNYHIKRCNAPCAGLISKEEYGEIIKKAVGLISGKNNDIIRELKEEMEKASMNLDFEKAADLRDKMLAAQKVTEKQKIIIGNFENEDYISLYSDEKDSCVQVFFLREGKIVGREHFIVENTAGENEGDIIGEFIKEFYSGTAYVPKSIYASAGEDLNLLENWLTMKRGSKVEIKIPQKGEKKDIIEMVKRNSKITLEKFKIKLLSDKRLNENILIEMTEVIGLEEVPHRIEAYDISNIQGVDSVGSMIVFEEGKPKNSDYRRFKIKTVKGANDYDSMREILTRRFKHGLEEVNSIVNKNLSLSAGKFCVFPDLILMDGGKGQVNIALEVLKEFNIDIPVCGMVKDDRHNTRGIIYNNNEIDIKSNRKIINFVTRVQDEVHRFAITYHRSLRDKRVLHSVLDDIPYIGEKRRKALLKHFGSIENIKKATYEELMKTPSIDKKAAESIVSYFRGRKGE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_HELPJ
Sequence: MSRNEVLLNGDINFKEVRCVGDNGEVYGIISSKEALKIAQNLGLDLVLISASAKPPVCKVMDYNKFRYQNEKKIKEAKKKQKQIEIKEIKLSTQIAQNDINYKVKHAREFIESNKHVKFKVVLKGRESQNSKAGLDVLFRVQTMMQDLANPEKEPKTEGRFVSWMFVPKAKEAPKNEKKTKENNPPFNRINLMKGENHAKNED
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPP2_BOVIN
Sequence: MAASTASHRPIKGILKNKSSTTSSVVSTAEQPGKSVDEELSKKSQKWDEMSILATYHPADKDYGLMKIDEPSTPYHSMVADDEDALSDSETTEALTPDILARKLTAAAAESLEPKYRVREQESSGDEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLNDEEEDEEMSETAAGESMNMEESSQGSATSDQLQNKSQSS
What is the function of this protein?
Inhibitor of protein-phosphatase 1.
What are the official names of this protein?
Protein phosphatase inhibitor 2, IPP-2.
What is the protein family that this protein belongs to?
Belongs to the protein phosphatase inhibitor 2 family.
Protein: SDCG8_DANRE
Sequence: MKPSLESDEEEELGALQKTLRERANRSIQHLSSMLAGHSSDSETSEPNQQELLSSVQQNPCSPVQQSEAVSQLRSLLQMKTKDANIQSLSPSRRKLAAKRATDDGSSSQPGVHNLVPIINNQSEYIQHLEAEVKFCKEELLEMKQRVRVVIVENEKLHHELKAKTIEDTLKEYTFVDSTLNMEHTAENTLKERLGSVNQAEDHKWRKEMEQLKCLYQAQTETLEAQVVSLKKDLACIQKEYEESKERLRHKEAMAVAAGTGQRVSGLCLKCAQHEAVLAETHTNVHVQSIERLTKERDELMTVLCSLRASQTDAQQREWGAYQQVKQAVEMAEEANLEKTRALVQCEHFHNELTRQRERLERELASEQDKISQAREAARSESKKEREELMQTLSSLSQKVAELQGLLDRGERDRNSLNSQLEEAYKKLTVQETDSSKMCAELRFLLSQAQLKKEEAERDVRDISSKLGRQLELAEQEVQKLGVELSGYRQRLEEAQRAEGRARAEAAGLAEGLSRAQRQLHLTRQEKEASERCCGEDMAALTFQAQRRERELTQTLQQMEAQHEKSVRETDALLSAQNSLIRKLKEECHTLGAKLEELAQSSRAEMEQLSLEREHLQESAEKLRGRCEEMEEQCVQHGRMHQRMKQRLQQLDQHCQASSQQVLQLLSRQKQLMQERQQLTEDLHSLKSQVHAGKRMDRLAV
What is the function of this protein?
Plays a role in the establishment of cell polarity and epithelial lumen formation (PubMed:20835237).  Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation.  Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis (By similarity).
What are the official names of this protein?
Serologically defined colon cancer antigen 8 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cell junction. Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.
Protein: RL6_PROMM
Sequence: MSRIGKNPIPIPDKVAVTLDGLAVSVKGPKGELSRTLPEGVSVSQVENTIVVTPTSQKRKSRERHGLCRSLVANMVEGVSKGYTRKLELIGVGSRAQVKGKKLVVSAGFSHPVEMDPPEGVTFAVENNTNVTVSGADKELVGNEAAKIRAIRPPEPYKGKGIRYEGERILRKAGKSGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: Y859_STACT
Sequence: MSKNDLVKTLRMNYLFDFYQALLTKKQRNYLELFYLQDYSLSEIADTFDVSRQAVYDNIRRTGDLVEDYETKLELYSKFEQRREIYNQMKASIEDPDALKRYIEELEELE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein Sca_0859.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: EX7S_STAAR
Sequence: MTKETQSFEEMMQELERIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_PHOPR
Sequence: MQTQRLRIAIQKKGRLSKECQDLLKRCGVKFNMMGERLVVHSENMPIDLLLVRDDDIPGLIMDGVVDLGVIGENELEEVGLERAARNEPSDYKKLRRLDFGDCRLSIAIDKDATYNGPQDLQGKRIATTYPQLVKRYMDKQGVTFSTCMLNGSVEVAPRAGLADAICDLVSTGATLEANGLKEAAVILRSKAVLIQCTAELSAEKQALIDRLLTRMQGVIQAKESKYIMLHAPTDRLEQIKMLLPGAEDPTVLPLSQNNNRVAVHLVSTENLFWETMEQLKELGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_PEDPA
Sequence: MANADLSNFDKIIVLDFGSQYNQLITRRIREFGIYSELLSHKITAEEIKKINPKGIIFSGGPNSVYDKDAFRIDPEIYKLGIPILGICYGMQLMTYNLGGRVEPADNREYGHADIDVTDDQAVMFKELPAKQTVWMSHGDLVREVPEGFKTVATSANCPIASMADDARKFYGVQFHAEVRNTQYGNEILRHFAFDVCEAKANWSMNDFIDMQVQQIRETVGDRKVLLGLSGGVDSSVVGVLLNKAIGDQLVCIFVDHGLLRKGEAKQVMDSLEGKFGLNIIKVDAQDRFLSKLAGVSEPEQKRKIIGNEFIQVFNDEAQKLKGIDFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMHFELIEPLRTLFKDEARDLGEKLGMPEDLVWRQPFPGPGLGIRVIGEITEDKLQIVRDSDLILREEIKKAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVNSIDGMTADFARIPWDVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GRPE_NITOC
Sequence: MANEERTIPETNVASERPEDPVESQTRAEGGEQIQEAAPETAELEAVQQLLEDARSKADEHWNELLRARAELENQRRRHERELEKGRKYALEKFAQDLLPVKDSLEMGLAAAQAEDANVTALREGTELILKMFNEVAARFGIETIDPQGEAFNPDFHQAISTQESSEAAPDTVLTVVRKGYALNGRLLRPAMVVVSKPGEQTTAGVDTQA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_LAGOB
Sequence: MTNIRKTHPLMKILNDTFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMSQETWNIGVLLLLAVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAAVHLLFLHETESNNPTGIPSNMDMIPFHPYYTIKDILGALFLILALLTLTLFTPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILVFIPMLQTSKQRSMMFRPFSQLLFWTLIADLLTLTWIGGQPVEHPYIIVGQLASILYFFLILVLMPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MUTS2_STRS2
Sequence: MNNKIIETLEFHKVRQKIEPYLLTEQGFEELRQLEPMVEVHRIQQAFDELTDIAQIFVENPYFSLAATSDIGPAMRRLELDTDLNIAELLAVKKVLEVSKSLLDFYGNLENVSLSQQLDKLFEKIELFPHLQGSLQSINDAGFVEDFASEKLARIRRKIREAEDQVRQVMQDILKTKGDMLSDSILASRNGRNVLPVKNTYRNKIAGVVHDISASGSTVYIEPRAVVTLNEEISHLRAEERHELNRILQELSDMLRPHGGVIRNNAWLIGHIDFVRAKHLFARDHQAVVPKLSEKQDIALLNVRHPLIAKPVPNDLYFGSQLTAIVITGPNTGGKTIMLKTLGLTHLMAQSGLPILADKGSRVAIFKEIFADIGDEQSIEQSLSTFSSHMTHTVEILRAADQDSLILFDELGAGTDPQEGASLAMAILDDLRLRGIKTMATTHYPELKAYGIETSGIENASMEFDSNSLRPTYKFMQGVPGRSNAFEIARRLGLSDIIIQSAQSWTDTDSDVNRIIEKLESQTVESRQRLDKIRDVEQENYKMNRALRKLYDELNRERENELNKARLEAKEIVDMALAESEDILKNLHAAASLKPHQIIEAKAELKKLAPEVVDLSKNKVLKKAKIKREAKVGDDIIVTAYGQRGTLTNQLKDGRWEAQVGLIKMTLAKDEFELVKAEKAEQPKKRQVHTVKRANVRGPKARLDLRGKRYEEAMMELDEFIDQALLNNLAQVDIVHGIGTGVIREGVTKYLRRNKQIKEFGYAPQNAGGSGCTIVTFK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: IPI3_YARLI
Sequence: MEELIIYTTNKGACAVDLHSGNNITHFKNDETAPNLSVFLTNTPSGNPLLFSAQTKGAMMHVYNWNRESVDQQIVLPEKLSCLAASTCGTWLAGGSASGRLFVWELASGKLVFSREVHYQAVTKLAFTDGLLFSTSKDARVLGWSLVTMASDPKDCQPCITWTEHNLGVVDLVVGGGPTRDTRVFTVSTDKTVRIWDVSSTALLTTITLPAAETPTTLAVDQLERTLFVGCASGNILSVSLYDVSPSTGLVSVGGASGVVESGNVALSHHKSAVTSLALSFDATLLVSADDKGFICVWDLPSRQVSRSIKQPRAEMNPVTYVQTITTHGLPTEKYNPKTAVKLPMLKRVQDDKPEDHDILVKIQPRQKTVAHEDTLQQMVESAQFGGDSLAGKVVQLENELSQAKSSFASLKESHDTLWNIYQRQQ
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat IPI3/WDR18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_SHIBS
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.