PharMolix/UniProtQA huggingface dataset:
Protein: CHP3_HUMAN
Sequence: MGAAHSASEEVRELEGKTGFSSDQIEQLHRRFKQLSGDQPTIRKENFNNVPDLELNPIRSKIVRAFFDNRNLRKGPSGLADEINFEDFLTIMSYFRPIDTTMDEEQVELSRKEKLRFLFHMYDSDSDGRITLEEYRNVVEELLSGNPHIEKESARSIADGAMMEAASVCMGQMEPDQVYEGITFEDFLKIWQGIDIETKMHVRFLNMETMALCH
What is the function of this protein?
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity.  Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane.  Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage.  Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.  Also involved in granulocytic differentiation in a ERK-dependent manner.  Inhibits the phosphatase activity of calcineurin.
What are the official names of this protein?
Calcineurin B homologous protein 3, Tescalcin, TSC.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family. CHP subfamily.
Protein: CVFC_STAS1
Sequence: MEIVRVEPTPSPNTMKIVLNEKRKDNKSNTYTTILDNQPKFINDVLAVDGVKSIFYVMDFLAVDKKPKYDWEVLLPKVTATLSDESESIDTPAPDEHFGEVKAEVLQFKGIPYQVKLTSSSEEKRKQLPEVYIDSMLAAQKDDDNIVFQRKWENLGIRYGELDDIMSEVTEEILALYPEKDLNHLVENALNTDVVIPEKKYQHVTLETYQATDDWKERLRMLKAFPTPTERDFPLLGDAVSEEEKTPLRREAIVLLGMIEDKAVLPYLFKGLHDKSPAVRRTAGDCLSDLGFKQALPEMEKALDDPHKIVRWRAAMFIFDEGGPEQLDALRTHENDPAYEVKLQIEMAIARIENGDEALGSVWKQIANRNKS
What are the official names of this protein?
Conserved virulence factor C.
What is the protein family that this protein belongs to?
Belongs to the CvfC family.
Protein: PRMC_BACTN
Sequence: MNRITAYIRQSLQDIYPPEEVKALSMLICCDMLGVDALDIYMGKDIILSACKQRELENIIFRLQKNEPIQYIRGYAEFCGRNFRVAPGVLIPRPETAELVDLIVKENPDARRLLDIGTGSGCIAISLDKNLPDAKVDAWDISEEALAIARKNNEELDAQVTFRRQDVFSADGIQGTSYDIIVSNPPYVTETEKTEMEANVLDWEPELALFVPDEDPLRFYRRIAELGRELLRPGGKLYFEINQAYGQDMIRMIEMNQYRDVRVIKDIFGKDRILTANR
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: RL35_STAAR
Sequence: MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CEA7_ECOLX
Sequence: MSGGDGRGHNSGAHNTGGNINGGPTGLGGNGGASDGSGWSSENNPWGGGSGSGVHWGGGSGHGNGGGNSNSGGGSNSSVAAPMAFGFPALAAPGAGTLGISVSGEALSAAIADIFAALKGPFKFSAWGIALYGILPSEIAKDDPNMMSKIVTSLPAETVTNVQVSTLPLDQATVSVTKRVTDVVKDTRQHIAVVAGVPMSVPVVNAKPTRTPGVFHASFPGVPSLTVSTVKGLPVSTTLPRGITEDKGRTAVPAGFTFGGGSHEAVIRFPKESGQKPVYVSVTDVLTPAQVKQRQDEEKRLQQEWNDAHPVEVAERNYEQARAELNQANKDVARNQERQAKAVQVYNSRKSELDAANKTLADAKAEIKQFERFAREPMAAGHRMWQMAGLKAQRAQTDVNNKKAAFDAAAKEKSDADVALSSALERRKQKENKEKDAKAKLDKESKRNKPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHHEKPISQNGGVYDMDNISVVTPKRHIDIHRGK
What is the function of this protein?
Colicins are polypeptide toxins produced by and active against E. coli and closely related bacteria.
What are the official names of this protein?
Colicin-E7.
What is the protein family that this protein belongs to?
Belongs to the colicin/pyosin nuclease family.
Protein: Y2817_PROMH
Sequence: MIIPWQELSTETLDNLIESFVLREGTDYGMQEKTLEQKVADVKKQLVSGEAVLVWSELHESVNIMPAAQFRPD
What are the official names of this protein?
UPF0270 protein PMI2817.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: TRUA_COXB1
Sequence: MARIALGIRYDGSAYHGWQVQEALKTVQGEVEKALSAVANHPVFVTCAGRTDAGVHASAQVAHFDTTAYRSDHAWVFGANSNLPHDISILWAKAVEEDFHARYSAMARRYRYIVYNHEIRPAILRKAIGWHYRPLDEKRMQAGAQYLIGEHDFSSFQGAGCQSRTPVRKIFQIEIYRIRRMVVIEVQANAFLLHMVRNIAGVLIAIGSGEKHPDWAQTVLKAKDRRQGGVTVPPNGLYLVEVNYPPNFKLPRMPLGPFFLP
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: KDGT_XANOM
Sequence: MRIKATVERLPGGMMLVPLLLGALCHTLWPQAGSTLGSFSNGLISGTVPILAVWFFCMGATIQLRASGRVLRRSGSLVLTKIAVAWLVAVVCAPLLPIGGIPSGPLTGLSVLALVAAMDMTNGGLYAALMQQYGSSEDAGAVVLMSLESGPLISMLILGASGLATFEPQLFVGAVLPLLLGFALGNLDAQLRQFFAQATQTLVPFFGFALGNTLDLSTIVHTGASGVLLGVAVIVITGLPLLLADRWLGGGDGTAGVAASSTAGAAVATPALIAGMAPQFAPAAPAATALVASAVIVTSVLVPLLTALQAGRSRQRIG
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOXP2_HUMAN
Sequence: MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
What is the function of this protein?
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium.  May also play a role in developing neural, gastrointestinal and cardiovascular tissues.  Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential.  Plays a role in synapse formation by regulating SRPX2 levels.  Involved in neural mechanisms mediating the development of speech and language.
What are the official names of this protein?
Forkhead box protein P2, CAG repeat protein 44, Trinucleotide repeat-containing gene 10 protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURA_CHLP8
Sequence: MNKLVIRGGKKLSGTVAASGSKNSALPVIAATLLTPDGTFGINRIPDLKDVRTFIQLLEYLGAAVSFENNRLEVSSSDLKSIEAPYELVKKMRASIYVLGPLLARFGHTRVSLPGGCAFGPRPVDLHIMAMEKLGATVTIEQGFIDAKVNGSRLRGAEIDFPISSVGATGNALMAAVTAEGKTVLQNAALEPEIECLCRFLQKMGANISGIGTTTLVIEGVDQLKAVEFDNIFDRIEAGTLLGAAAITGGSVTVTGTVPEHLGSVLDAFRQAGCIVTVKDDAITLTAPEELQPVDITARPYPEFPTDMQAQWMALMTQAHGDSTIIDRIYLERFNHLPELNRLGAHIEIRDNWALVHGPQELTGTKVMSTDLRASACLVLAGLVAKETTEVLRVYHLDRGYESIEKKLSALGADIKREQYQEFS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERF4_NICSY
Sequence: MAVKNKVSNGDLKGGNVKTNGVKEVHYRGVRKRPWGRYAAEIRDPGKKSRVWLGTFDTAEEAAKAYDTAAREFRGPKAKTNFPLPSENQSTSHSSTMESSSGETGIHAPPHAPLELDLTRRLGSVAADGGDNCRRSGEVGYPIFHQQPTVAVLPNGQPVLLFDSLWRPGVVNRPQPYHVMPMAMGFNGVNAGVDPTVSDSSSVVEENQYDGKRGIDLDLNLAPPTEF
What is the function of this protein?
Transcription factor that binds to the GCC-box pathogenesis-related promoter element.  Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.  Probably acts as a transcriptional repressor and may regulate other AtERFs (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor 4, Ethylene-responsive element-binding factor 3, EREBP-3, Ethylene-responsive element-binding factor 4 homolog, NsERF3.
What is the protein family that this protein belongs to?
Belongs to the ethylene-response factor family. Class 2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTC_STRSY
Sequence: MTNVFKGRHFLAEKDFTRAELEWLIDFSAHLKDLKKRNIPHRYLEGKNIALLFEKTSTRTRAAFTVASIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQKMVEELAEFSGVPVWNGLTDAWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEVVALAEGFAKESGARVLITDNADEAVKGADVLYTDVWVSMGEEDKFAERVALLKPYQVNMELVKKAENENLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGDPFVPRV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_MYCGH
Sequence: MSNTSNFNERVTENAKPPKNVKSIIWKTIGIIIVMAIIIGLILFYVLPRNTIANISNIQYVDGNLVATATINGRSGRFILDLENSTYQTSYTSGLSLSISVFLRNLNNANGQSFFVSLIRPATSSANDAVFNIANLSINQTRGVATLVTEGGSYSAVLTTTLTALPLTGQKFLPEGFNLDTANTDAYRAAGAIPGIQRLLAVGNVQLPNQSTAILTQFLTSIIPFVILIVIYIVIARRFSRTMGAGGAIGEDGENVFTIGKSQAKLAKSTFKFTDVAGIEEEKSELIELVDYLKRPGKYVQMGARTPRGVVLYGPPGTGKTLLAKAVAGEAGVPFFQVTGSAFEDMLVGVGAKRVRNLFAKAKKAAPCIIFIDEIDSVGSKRGKYEISAGSATDQTLNQLLAEMDGFSTRTGIIVMAATNRLDVLDDALLRPGRFDRHIQVNLPDIKEREAILKIHSRNKNISSKVNLLDIARRTPGFSGAQLENVLNEATLLAVRADRTSISLTDIDEAIDRVIAGPAKKSRVISDFEKNQVAHHEAGHALVGLHLKGADEVQKITIIPRGQAGGYTLSTPKDAELNLKKKSDLLNMIAGALGGRASEELFFGKDAISTGASNDFYKATNIAKTMVTQLGMSDLGITQFLPSEGGINPNARYYSENTAQRIDEAIAKILEEQYQVAYNIIKDNQNELKLIVEALLIQETIVKNDIDYIHEHLKLPEAIIKLKEEQLKEKAAAEKEEQAEKAKLDHQSDSAQPQEEPTASTASSN
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: ROT_STAAW
Sequence: MHKLAHTSFGIVGMFVNTCMVAKYVIINWEMFSMKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILLTLWQKGSMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQQEKVELLNFISDAIASRATAMQNSLNAIIAV
What is the function of this protein?
Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence.  Also, modulates the expression of genes not previously implicated in pathogenesis (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator rot, Repressor of toxins.
What is the protein family that this protein belongs to?
Belongs to the rot family.
Protein: AURK_DICDI
Sequence: MSYPNNKENSNNIGGGSFSVPSKQPQRVLQQQNTNINNHQTTSTVKSTITKPTTTGATTSTNTSTIPPTTTASSSSSSSSSSSSSSSSSSSSSSSSSQSVPKKKWCIDDFDIGKLLGMGRFGHVYLAREKKSQFIVALKVLFKNQLQTHNIEHQLRREIEIQSHLRHPNILRLFGYFYDDKRVFLIIEFAKGGECFKELQKVGSFNEQTAATYTLQIADALRYCHSKHVIHRDIKPENLLIGVGGEIKIADFGWSVHAPNTKRSTFCGTLEYLPPEVIEKKGYDQTADVWSLGILIFEFLVGRSPFTSDEEKNIFHNIQENDVYYPSSISPEAKDLISRLLVSDPHQRITLKDVINHPWIKKHAHPKSLEPTKLGLPLPSQMTY
What is the function of this protein?
Part of a chromosomal passenger complex.
What are the official names of this protein?
Aurora kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Cleavage furrow. Cell projection, neuron projection. Note=When cells entered mitosis, found at spindle poles during prometaphase. With the onset of anaphase, localized at the central spindle and remained there during telophase and early cytokinesis. At the end of cytokinesis, localized at the cytoplasmic bridge and eventually to breaking points. Also found at the cleavage furrow, late in cytokinesis, when the furrow becomes a thin cytoplasmic bridge.
Protein: HISZ_MARMS
Sequence: MTLADRWLLPEGVDEALPEQAAKIEHLRRTLLNLHESWGYHLVIPPLLEYLDSLLTGAGSDLEIETFKVIDQLSGRLLGIRADFTSQVARIDAHCLKDDGVQRLSYCGSVLRTMPAGLDGTRSPIQLGAEIYGHGGVESDVEVLSLMLQTLSTAGLSNLVLDLGHVDIVSGVLAACNLNADQESKLIELYKAKDLPELDRYAEELGCLTDIQKQWLVGLPRLCGGKEVLKHATDLLGDVNESIRDAIVLLQKVSDSICQRFPKVGLHFDLSDLVSYSYHTGVIFAAYVPGHGNAIARGGRYNNIGQVFGRSRPATGFSTDVKALVALTDIVVNKPKTVLSPICSSDELWQKANSLRAEGYRVVEVLDDICAGDADFKLEFVDEAWQLMPVHN
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQR2_CAEEL
Sequence: MAEKILFYIYRDSGTSSENLVRAIVDEFKNFVFRDRGIAFTSKGYSGIPLLGELPIDSPLDDIWKVVAVLFKISAREEGLIFKVHTTDYEKNPLVAEAKKSDVLPNWAHSVKDFAENVFGMNGVIHLISPTVSEKFPKRSQIDILRAVPNETRNILVTESLSEKLHSSESRNFGMHNTSVNVPVSMAYVARERPDILSLAIREFVKTDERKIKELEKRLANEHDRVMIHTIINDTDWKEVTAVADIESPTDIVSHRVSLALLAFDEKHSSIPNGVDVPVSGLFQKVGDRFEREHLEALRAKLFGSPQSATHLYQCAKSLVTGNHVQECRKIFVDEGSTSNRESDCSGNEDDSSNAKYAKKQVFKKKKRNAFGKKRELAAILDHTKPSEHSEPDYVAPDNSAALKKFERAVNGDDYYKASSDEYSLGEEEDLELFMAKPRKKILEEMKNKNKARLGIKVTERLPTVSDDEEIDVADMLRAAPPIANAEDIEDFDDI
What are the official names of this protein?
Uncharacterized protein F19C6.2.
Protein: RS18_PSEPG
Sequence: MARFFRRRKFCRFTAEDVKEIDFKDLNTLKAYVSETGKIVPSRITGTKARYQRQLATAIKRARFLALLPYTDSHGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TCTP_SCHHA
Sequence: MNFREERYDTIMFTDSHCPRVVADFFYEVESRFTTASSKVDGRLIGANPSGEGEDDEDVDDTSERVIDLVHANGFISVPYDLKSYKAQLKSYLKAIKERLQKTVPDKLPLLESQVNKYRKDVFANFDQYECFTGPSTNPEAMVVLMNFVCGR
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITPA_ORYSJ
Sequence: MSGAAAAAARALPKAVTFVTGNAKKLEEVRAILGSSIPFQSLKLDLPELQGEPEDISKEKARMAASQVNGPVLVEDTCLCFNALKGLPGPYIKWFLEKTGHEGLNNLLLAYEDKSAFAMCIFSLALGPGEEPMTFVGKTAGKIVPARGPADFGWDPVFQPDGFDQTYAEMPKSVKNQISHRGKALALVKEHFAAANYKVQNDGSA
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROQ_PASMU
Sequence: MTEVQKLTNNKEVIAYLVEKFPLCFSLEGEAKPLKIGLFQDLAEALQDDERVSKTQLRQALRAYTSNWRYLHGCKAGAERVDLQGNVCGILEQEHAEHAAQQLAEAKAKVAAMRAAEKAAKPEKKRPARRVAAKGQHAKETTTNKAKVTRKPKVILNAIELASLQKGDSVKVKVGESAKKAIVLEVVKDSARVQLENGLVITVTAEHLFA
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_KLEP7
Sequence: MTTEIRALYTRLPAIDRLLRDPAFSPLLAQHGHSQVVAQLRQMLDEAREQISQRQTLPDWSHDWQHACEQRLTAGQRSALRPVFNLTGTVLHTNLGRAIQAESAVEAVASAMRAPVTLEYDLDDAGRGHRDRAIADLLCQITGAEDACIVNNNAAAVLLMLAATASGREVVVSRGELVEIGGAFRIPDVMRQAGCQLHEVGTTNRTHAKDYRQAVNDNTALLMKVHTSNYSIEGFTKAVDEAELAAIGRELDVPVVADLGSGSLVDLSQYGLPKEPMPQEMIAAGVSLVSFSGDKLLGGPQAGIIVGKRALIAQLQSHPLKRALRADKMTLAALEATLRLYQHPEALREKLPTLRLLTRPAEEIRRLAERLQPDLAAHYADFAVSVAACQSQIGSGSLPVDRLPSAALTFTPHDGRGSRLEALAARWRALPCPVIGRIYDGRLWLDLRCLEDETRFMEMLLR
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASO_TOBAC
Sequence: MASLGFLFFFLLPLILLELSSSRSVMAAKTRHFKWDVEYIHWSPDGEESVVMGINGQFPGPTIRAKAGDTVAVHLTNKLHTEGVVIHWHGIRQIGTPWADGTAAISQCAINPGETFLYRFKVDKAGTYFYHGHYGMQRSAGLYGSLIVEVGEGEKEPFHYDGEFNLLLSDWWHKGSHEQEVDLSSNPLRWIGEPQTLLLNGRGQYNCSLAARFSKPPLPQCKLRGGEQYAPQILRVRPNKIYRLRVASTTALGSLSLAIGGHKMVVVEADGNYVQPFSVQDMDIYSGESYSVLFKTDQDPTKNYWISINVRGREPKTPQGLTLLNYLPNSASKFPTLPPPIAPLWNDYNHSKSFSNKIFALMGSPKPPPQNHRRIILLNTQNKIDGYTKWAINNVSLVLPTQLYLGSIRYGINAFDTKPPPDNFPKDYDVLKQAPNSNSTYGNGVYMLKFNTTIDIILQNANALAKDVSEIHPWHLHGHDFWVLGYGEGKFSEKDVKKFNLKNPPLRNTAVIFPFGWTALRFVTDNPGVWAFHCHIEPHLHMGMGVIFAEGVHLVKKIPKEALACGLTGKMLMSNKHN
What is the function of this protein?
May be involved in a redox system involving ascorbic acid.
What are the official names of this protein?
L-ascorbate oxidase, ASO, Ascorbase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSA_RHOPA
Sequence: MTIEVRNIVKEFGSFRALDNVDLRVETGELMALLGPSGSGKTTLLRIIAGLEWPDSGVVTIDGEDALAHGAAERHVGFVFQHYALFRHMNVFENVAFGLRVQPRKIRKSEAEIKKRVGDLLDLVQLGWLADRYPNQLSGGQRQRIALARALAIEPRILLLDEPFGALDAKVRKELRAWLRNLHEEIHVTSIFVTHDQEEALEVANRVVVMDKGRIEQIGSPGDVYERPASAFVHGFIGESIVLPVEVRDGRVRLGDRDLDLGAQDAAAGPSKLFVRRHDVTVGPSGSGVFEGAVKAVRAFGPMQRADIVLNDLGSDTLIEIDAPRDHSLKVGDRIGLQPQRYRIFADR
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS2_METM7
Sequence: MNVLKEVYSTIEKRIQEKPEGSYVVKLTTDDKKTAVNKICEKIGEEAAEVIIAAKDDDKAEIIYESADLIFHTMVLLAKSGITYEELSEEFKKRMK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRBG2_HUMAN
Sequence: MEEAGGPMARAKARVVSATLTWRQRPPTQEEIKHGFHKVSLVSGAQMEAPQKEMFEFSRREEVEVNGFATQEEETVNCQGPRDTAGSKNFQSHGPIFSKKYIPPPKEKRPEGRLKEAVDQSDGSRQAPRTEPPCVGAMARTELLVPLPGPREPSPHPGVGLTSGSSRSLEEYRVTRTVRTTTVVGGHVDRRMSSSVTVRPVSSGEALPRGRQVSRMVPPVVVGSPPGSPSRSQAVKVLSNLVPAGHSPPASHLPRPTAGGPRSTGLGSTVGAALRQLPETGTAELKDSSALASTGIPASAHLPKNQDAPAACPDRDQGRAPDARACELWQVLGAPSSTELPLQTSQGQASVPSSPRLETHVPSPGLTHPAKQPVVPTHPGARLTPLVLPPKKKDGPVDPPAATVLPMVRSEHVTVPGQPPAPSTTRRKDVPSPGGLSAPSSPRNKFVQNSENVPVLPFTQREVVKGPGAPAASSPTRKEVVQGSSASAASSPTWKEVVKGPGAPAASSPTQKEVVQGSSAPAALFPTWKEVVKGPGAPDASFPTWKEVVKGPGAPAASSPTQKEVVQGSGAPAALSTTPKEVVKGPGAPAASSPTQKEVVKGPCAPAASSPTQKEVVQGSGAPAALSPKSTEVVQGPKGSSSIQKEAVQGIAGSLAPPLTKEETVQGPIAPATSLPKQDKGVQDSEGSPISSLTQKEVVQDPDALPAPSSSVDRVSPSPGGTPAPVPTGAEASTESQLVSDPTEGKTCTETSREEDEVALAADLEIFLDTLRSMEPPEILRTHRLPRAPRSSYLSMYATLPAIEEDQLGPWVLGPGPQEVPSLEEKEEEEEEEPENPYLSDDEKLQRRQEKAGPSPSRDLHPARPTQVSCSPLEMMKKHVAGTKGPHSELGLELQGGSRPTSRLGGSLLFGSLVPTAKEASTPEPLGTKLSALLPHGAPGLRKVPGQLPLLCSERSSPTEKLACSLPLEGWSPALKTQGKLNTRPGKVIFFSESGCQGSGREVWGDIVDASGWAPVASIRVVRGCWVLYEEPEFRGQKLVLPEGDMELRTPGTKWSPQGIGSLRRVVWDYSTPEISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEPGEYPTSEAWGTSDPSVGSLKPMRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYDELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQAALPASFRPQSCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMGCLASTVLGSLQKVSLHFSEPSIFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCEITNWLTYSGTQRVGSLYPIKQRRVYFRLWNAALGGFLAVPDHVEDMKAGRVVVADPQAGGSCIWYYEDGLLKNQMAPTMSLQVIGPPSPGSKVVLWAESRLPRQTWSISESGHICSQMFEGQILDVKGGRGYDRDHVVLWEPDEDRASQIWTIHVL
What are the official names of this protein?
Beta/gamma crystallin domain-containing protein 2, Absent in melanoma 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: CAS2_CONST
Sequence: MGMRMMFTVFLLVVLATTVVSFPSDRASDGRDDEAKDERSDMHESDRNGRGCCCNPACGPNYGCGTSCSRTL
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (PubMed:1390774).  This toxin potently inhibits the rodent muscle nAChR (IC(50)=120 nM (adult subtype, alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and IC(50)=370 nM (fetal subtype, alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND)) and weakly inhibits neuronal nAChRs (PubMed:35357806).  In contrast to alpha-conotoxins bearing 2 disulfide bonds (framework I), this conotoxin acts via a unique binding mode with the helix and the N- and C-termini buried in the binding pocket of muscle nAChRs (PubMed:35357806).
What are the official names of this protein?
Alpha-conotoxin SII.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.