PharMolix/UniProtQA huggingface dataset:
Protein: GREA_MYCTA
Sequence: MTDTQVTWLTQESHDRLKAELDQLIANRPVIAAEINDRREEGDLRENGGYHAAREEQGQQEARIRQLQDLLSNAKVGEAPKQSGVALPGSVVKVYYNGDKSDSETFLIATRQEGVSDGKLEVYSPNSPLGGALIDAKVGETRSYTVPNGSTVSVTLVSAEPYHS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: CUTI_KINRD
Sequence: MLRARPSHRLASAAAVVAATGAALLAGSSPAAAATCSDVDVVFARGTGETPGLGVVGGPFVRSLTGELSDRTVTSHAVDYAASSSQASAGPGATAMSAHVREVAAACPSTRFVLGGYSQGATVTDIALGIRTGTTTGTPVPAELAGRVAAVVVFGNPLGLSGRTIATASSTYGPKSKDYCNSSDSVCGSAPKTGTGGHLSYASNGSTTDGARFAAGLVRAAGTPTTPTPTPTPTPVPTTCVRDSTRDHVAADRAVSLYGRAYARGSRDSLGATSSYNVVSLQQVEGGWRLVTAC
What is the function of this protein?
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle (PubMed:34705546).  Shows esterase activity towards p-nitrophenol-linked aliphatic esters (pNP-aliphatic esters) (PubMed:34705546).  Can depolymerize synthetic polyesters such as poly(epsilon-caprolactone) (PCL) and poly(1,3-propylene adipate) (PPA) (PubMed:34705546).  Exhibits some activity on poly(lactic acid) (PLA) (PubMed:34705546).  Can bind but not hydrolyze poly(hydroxybutyrate) (PHB) (PubMed:34705546).
What are the official names of this protein?
Cutinase, KrCUT.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CND2_MOUSE
Sequence: MRIPRSETMNSSFLKARGQQDVLSSPLERVPPASRPGKAPLGTPKTPVLEDFPQNDDEKERMQRRRSRVFDLQFSTDSIHLASPNRNIDVSTTISKFTNTQITEHYSTCIKLSSENKITTKNAFGLHLIDFMSEILKQKDAEPTNFKVAAGTLDASTKIYAVRVDAVHADVYRVLGGLGKDTPPQGEESHSGDGSTLETERTKKPAKPKKKQSCKTIEQNLSNINVSEADGKCAVDPMFQKTAASFDECSTTGVFLSTLHCQDYRSELLFPSDMQTLSSGEPLELPDLGFVDMTDLEASLQQCVEDRPLCPSLAGFQFTKWDSETHNESVSALVDKFKKNDQVFDINAEAEDDEEDVPDGPLVEDFVDNDEPDLSAAGDHEEFRSWKELCQVQSNQEEVISLEDRDIQVMCSFLSMKPGEYSYFSPRTMKMWAGPDHWRFRPRPKQDATSCTEHKKKSAKKDFEINFDDDIDFDAYFQKTKAATILTKSTLENQNWKATTLPTDFHYETDNLIQLHLKPGKRSLKMDQDQKAKTEHYEEIEDYDYNNPNDTSNYCPGLQAADSDYEEADDLFADPVGTLDLESDPKTTQENGHISPENQGVDITTYQELNLVAEPQKVNKIEIHYAKTAKKMDMKKLKQSMWSLLTKFSRKEADTEANHTESGQEGAPEEVADEKKLSGLTKDLQTRLPPLMAQNLSIPLAFACLLHLANEKNLKLEGTEDLSDVLVMQGD
What is the function of this protein?
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.  Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.
What are the official names of this protein?
Condensin complex subunit 2, Barren homolog protein 1, Chromosome-associated protein H, mCAP-H, Non-SMC condensin I complex subunit H, XCAP-H homolog.
What is the protein family that this protein belongs to?
Belongs to the CND2 (condensin subunit 2) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).
Protein: PYRB_NEIG2
Sequence: MPNPLYRQHIISISDLSREQLECLLQTALKLKAHPRGDLLEGKLIGSCFFEPSTRTRLSFETAVQRLGGKVIGFSDGANTSAKKGETLADTARIISGYTDAIVQRHPKDGAARVAAEFSRVPVINAGDGTNQHPSQTLLDLVTIYETQGRLDKLKIAMAGDLKYGRTVHSLCQALKRWGCEFAFVSPPSLAMPDYITEELEEADCRYRALGSLEEAAEWADILYMTRVQRERFDEQEFAKIQGKFNLEASMLARAKPNLRVLHPLPRTDEIHPDVDAAPHAYYFEQATNGVYARMAILSLVLNEEV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MYPT2_MOUSE
Sequence: MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPAERQGAGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGRIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQDVLRSEKETRNKLIESDLNSKFQSGLFKNKEKMLYEEEIPKSQDTEEENKESSSSSSEEEEGEDEVSESETEKEADKKPEATVNHSNSEIKSRIMEQIPAPAQNTFSASSARRLSSLFNKAEEPKDESPSSWRLGLRKTGSHNMLSEVANSREALRDRGSSIYRSSSSPRISALLDDKDKERENKSYFSMLVPRRLSSTSDIEEKENRESAVNLVRSGSHTRQLWRDEAKGSETPQTIAPSTYTSTYLKRTPYKSQADSTAEKTADSVSSSTPLCVITNRPAPSTANGVPAATVFSSAGTDPSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAEKTFSRSRAERQAQEQPGEKLEDPGGLEGSTKKQEPSAAPTKGAGEGRSLEEEPIYHRLRYPTQPDKPTTPVSPSASRPSLYTGSHLLRTSRASGPDSENSETSTHATAAKEMDTSEKGEADLDDQSSNRLSVRERRRAKDRRRGTGINFWTNDEDETDVSEEVKEALHERLSRLESGGTNPTSSDSYSDRASARARREAREARLASLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKAKLEKMAQQKQEKTSDRSSVLEVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK
What is the function of this protein?
Regulates myosin phosphatase activity.  Augments Ca(2+) sensitivity of the contractile apparatus (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 12B, Myosin phosphatase-targeting subunit 2, Myosin phosphatase target subunit 2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Note=Along actomyosin filaments.
Protein: THIL_SHIZO
Sequence: MSTPSIVIASARTAVGSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLPAGEGQNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMSMAPHCAHLAGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFAVASQNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGATLDSMAKLRPAFDKEGTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASRKALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARILNTLLFEMKRRGARKGLATLCIGGGMGVAMCIESL
What are the official names of this protein?
Acetyl-CoA acetyltransferase, Acetoacetyl-CoA thiolase, Beta-ketothiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIT2_RAT
Sequence: MSKRLRSNDVCADCSGPDPSWASVNRGTLICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYSNGANSIWEHSLLDPASVMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTHDSSGKTPVDYARQGGHRELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQGSPLSRSKDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASRTNRQKSLDSDLSDGPVTVQEFMEVKHALVASEAKRQQLMKVNNNLSGELRIMQKKLQTLQSENSSLRRQATASACQVQTASDHKDTVSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANHPEESRTRLQPFPTHIGRSALVTSSSSLPSFPSTLSWSRDESTRRASRLEKQNSTPESDYDNTAYDPEPDDTVSGRKGRQRSMLWQGDGPLPDTAEPHAVPSPALPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHAAVTEMAALFPKKPKSDTVRTSLRLLTASAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENSS
What is the function of this protein?
GTPase-activating protein for ADP ribosylation factor family members, including ARF1.
What are the official names of this protein?
ARF GTPase-activating protein GIT2, ARF GAP GIT2, Cool-interacting tyrosine-phosphorylated protein 2, CAT-2, CAT2, G protein-coupled receptor kinase-interactor 2, GRK-interacting protein 2.
Protein: RPPH_ACIAD
Sequence: MIDSEGFRPNVGIILANDNGQVLWAKRIGHNAWQFPQGGIHFGETPEQALYRELREEVGLLPEHVQIIAQTKGWLRYRLPHRYIRPDSDPVCIGQKQKWFLLKLTASTRHIQLNLSDPPEFDEWQWVSYWYPLGQVVNFKRDVYRKAMMELCMLLPQQQTFEKSSL
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: BCHL_RHOCA
Sequence: MSPRDDIPDLKGFDGDGEGSVQVHDSEDIGLDVGGARVFSVYGQGGIGKSTTSSNLSAAFSLLGKRVLQIGCDPKHDSTFTLTGRLQETVIDILKQVNFHPEELRPEDYVTEGFNGVMCVEAGGPPAGTGCGGYVVGQTVKLLKQHHLLEDTDVVVFDVLGDVVCGGFAAPLQHADRALIVTANDFDSIYAMNRIIAAVQAKSVNYKVRLAGCVANRSRETNEVDRYCEAANFKRIAHMPDLDSIRRSRLKKRTLFEMDDAEDVVMARAEYIRLAETLWRSTGEPGLTPEPLTDRHIFELLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: PER1A_ARMRU
Sequence: MHFSSSSTLFTCITLIPLVCLILHASLSDAQLTPTFYDNSCPNVSNIVRDTIVNELRSDPRIAASILRLHFHDCFVNGCDASILLDNTTSFRTEKDAFGNANSARGFPVIDRMKAAVESACPRTVSCADLLTIAAQQSVTLAGGPSWRVPLGRRDSLQAFLDLANANLPAPFFTLPQLKDSFRNVGLNRSSDLVALSGGHTFGKNQCRFIMDRLYNFSNTGLPDPTLNTTYLQTLRGLCPLNGNLSALVDFDLRTPTIFDNKYYVNLEEQKGLIQSDQELFSSPNATDTIPLVRSFANSTQTFFNAFVEAMDRMGNITPLTGTQGQIRLNCRVVNSNSLLHDMVEVVDFVSSM
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase C1A.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted. Vacuole. Note=Carboxy-terminal extension appears to target the protein to vacuoles.
Protein: Y3201_ACIBS
Sequence: MTKQYMTHRCLIAPPEMADDFFANTVIYLARHDEEGAQGIIINRPAGIQIKELLNDLDIDADNVNPHEVLQGGPLRPEAGFVLHTGQPTWHSSIAVGENVCITTSKDILDAIAHNEGVGRYQIALGYASWGKNQLEDEIARGDWLICDADMDLIFNLPYDDRWDAAYKKIGVDRTWLASEIGHA
What are the official names of this protein?
UPF0301 protein ABSDF3201.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MNME_CHLTE
Sequence: MSPSDLHLPVPGHPIAAIATPVGVGALAIVRISGAGVLDLADRVFRKVHGSGKLAEAAGYTAHFGRLYDGEEMVDEVIALVFRAPRSFTAEQMVEFTCHGGPVVVGRVLRLMLDNGCRLAEPGEFTRRAFLNGRIDLLQAEAIGEMIHARTESAYRTAVSQMKGDLSVRLGGLREQLIRSCALIELELDFSEEDVEFQSRDELTMQIETLRSEVNRLIDSYQHGRIVSEGVSTVIAGKPNAGKSTLLNTLLGQERAIVSHMPGTTRDYIEECFIHDKTMFRLTDTAGLREAGEEIEHEGIRRSRMKMAEADLILYLLDLGTERLDDELTEIRELKAAHPAAKFLTVANKLDRAANADALIRAIADGTGTEVIGISALNGDGIDTLKQHMGDLVKNLDKLHEASVLVTSLRHYEALRNASDALQNALELIAHESETELIAFELRAALDYVGQITGKVVNEEVLNTIFDKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_WIGBR
Sequence: MNILLSNDDGIYSPGIQKLSKKLKKFLNVQVIAPSCDKSGSSSSLTINNPLKVHKFSNGDITVYSGTPIDCVYLGINFFMKPKPDFVVSGINLGANLGDDVFYSGTVGAAMEGRYLKYSSLAISLDGNKHLDVAVEIVYKFLKFLLNNPFRKKYILNINIPDSPLKYIKGFKITKCGRKNFKNTVIKSKDSENKNIFWIGPKTNCYNESIGTDFHAIKNNYISVTPLLSNLTNNKEINSISNWFENFYKS
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_AQUAE
Sequence: MEQTLRVSVFGATGYTGIELLRSLLTHPHFEVKNLISQSYKGKKVREVLPFFSNTYISEIEFLEEPVEDYELAFLCLPHEVSYEIVPKLLSQGKKVVDLSGAYRIKSPKAYEEFYGFKHEREDILQRAVYGLPEVFREEIKNSDLVANPGCYPTATLLAIYPFLKERVGIESVIVHALSGVSGAGRKPKQQFHFPEMTENFFNYAVEKHRHTPEMEDVIRRVYGREVKVRFTPTVVPTSRGMISTVYLKSEKLNVKELFKEVYEDEIFVKVVDEPPQTKWVLGTNYCFIYPHYDERTGYYVIISAIDNLGKGASLQAVQNANLMFGLAEDDGLLQLPVFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_GEOSL
Sequence: MITTLTCPRCRAETVWEGNPHRPFCSARCKTVDLAAWADEEYRIAGPEAPSDNDENDRE
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: RIMO_ACIC1
Sequence: MPASRTVRLIRLGCARNDVDAEELAARLVDAGWRLTEAPSADVTVVNTCGFIEAAKQESIDTLLEAADGSTRVVAVGCLAERYGAALADAMPEATILSFDDYPVIAQRLEDVLAGRPPAPHTPRDRRTLLPLTPVDRPRAAAEVGIPGHLGGPRVLRHRLDDSPVAPLKIASGCDRRCTFCAIPSFRGAFVSRPPADILREAQWLADHGAREIVLVSENSTSYGKDLGDPFALEKLLAAFGGVDGLVRVRVTYLQPAEVRPALIDVIATAPHVAPYFDLSFQHASPRVLRRMRRFGGSEEFLNLLAEIRRRNPRAAVRSNVIVGFPGETEEDVAELGEFLRAARLDGIGVFGYSDEDGTEASGFPEKIPEQEIRSRVDDIAGIAEEVTADRARARLGETVDVLIDGVDDDRPDACYGYTEVQAVDVDGVTVLRDCSAARGALVRAEIVEIDGVDFLAAPVTGSTAGTPSGATVEG
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_BACMK
Sequence: MARKTNTRKKRVKKNIEAGIAHIRSTFNNTIVTLTDTHGNALSWSSAGALGFRGSRKSTPFAAQMAAEAASKVAMEHGLKTLEVTVKGPGAGREAAIRALQAAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PG062_VACCT
Sequence: MNSHFASAHTPFYINTKEGRYLVLKAVKVCDVRTVECEGSKASCVLKVDKPSSPACERRPSSPSRCERMNNPGKQVPFMRTDMLQNMFAANRDNVASRLLN
What is the function of this protein?
Plays an essential role in virion assembly and morphogenesis.  Also plays a role in the inhibition of host immune response by dysregulating mTOR.  Sequesters host RICTOR and RPTOR, thereby disrupting mTORC1 and mTORC2 crosstalk.  In turn, blocks the host antiviral response in part through mTOR-dependent degradation of cGAS, the primary poxvirus sensor.
What are the official names of this protein?
Phosphoprotein OPG062, Phosphoprotein F17.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG062 family.
Protein: DAPA_PEDPA
Sequence: MLENVDLISAIITPFDDQLKINFTALERLTNHLIETGNTGFIIGGTTGETPTLTHAEKLGLYTRFAEIVAGRVPIIAGTGSNNTQATIDFTKEVRQIDGIIAALVVTPYYNKPNQRGMVAHFKTVARQADFPIMMYNIPGRTGVQMENATIVELSQEPNIIGIKQCTNLNDIGFLVENTPNDFAVYTGNDPETLGAVALGANGVASVASHIYGYQIRALLDAVKHGDLLKAGKLQRELTPKMEALFLYPSPAPVKAVLNAQNWSVGSPRLPILPLNQKEKLNLAHQLGVNHLADVQLHY
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_YERPB
Sequence: MSVLQVLHYPDERLRKIAAPVKEVNGEIQRIVDDMFETMYAEEGIGLAATQVDVHQQIIVIDISENRDQRLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELETDGLLAICIQHEMDHLIGKLFVDYLSPLKRQRIRQKLEKMAKLNARAN
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PWAPL_LOTGI
Sequence: MNHLWLFIVTVSCIYLVYGQGEESVPCKVKFMGTACPLGRLVCEEDGDCLGVNQVCCYDGCGTTCHNKTTTLIPSTTQPQIQPIIPSTQPQIQPIIPSTQPQIQPFIPSTQPQIQRIIPSPELLCPVVTVRYAFCRFSTYTPCHTSNDCAVPGMKCCPDVCGKRCKFPINSTDHQQFQQTPLKPTVPLPQYQQTPLQPTVPSSQPPLQPTVPSPQSYNYKGACST
What are the official names of this protein?
Perlwapin-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: BEND7_HUMAN
Sequence: MEFSERKRSRKSQSFKLVSRDYHHEVYKIPEFSNDVNGEAKETQPIFLGDESMEIKKQITGMRRLLNDSTGRIYQRVGKEGEKLKEEPQDLDLVWPPRLNSSAEAPQSLHPSSRGVWNELPPQSGQFSGQYGTRSRTFQSQPHPTTSSNGELPVVNSSAGSNCCTCNCQSTLQAILQELKTMRKLMQIQAVGTQNRQQPPISLICSQRTAVSRKRNKKKKVPPKTVEPLTVKQKPSGSEMEKKSVVASELSALQAAEHTSPEESRVLGFGIVLESPSSDPEVQLAEGFDVFMPKSQLDSILSNYTRSGSLLFRKLVCAFFDDKTLANSLPNGKRKRGLNDNRKGLDQNIVGAIKVFTEKYCTANHVDKLPGPRDWVQILQDQIKLARRRLKRGSEIADSDERLDGIALPPTGACGGPCTVLPGGSAAVTLVLQSSPQTMSQEKGQMAEPWEEQHLVLLNNLTRDRAETGALSQTSQDFKHHSFLITQVSATLHHQRGIRNFPTPGSAKSLTLHISCLSL
What are the official names of this protein?
BEN domain-containing protein 7.
Protein: DHYS_PYRCJ
Sequence: MREVVELYKRIGGFQALHVAQAYEVLKEALGEADVRFFSFTGNLVATGLREIIAEALRERLFNVVVTTAGALDHDIAKAMGASYRPGSFDLDDYELAEKGLHRLGNVVISREEYGPYVEKFVLQRCERLWGRSLATYELAEEFGRDLPEDSILGAAARAGVKVFVPGIVDGAVGTALLTCNDLARVRRGGARLVVDVLKDEEALREIVHGGKRLAALIVGGGISKHHVIWWAQFKGGLDYVVYISTAVEYDGSLSGARPREAVSWGKVKPTAKSVYVYADATLVLPILLKALCGK
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: UBIA_JANMA
Sequence: MNRLQLYFRLIRLHKPIGILLLLWPTLWALWMASDGKPDWTLVAIFTLGTVLMRSAGCAVNDYADRDFDKHVQRTVDRPITSGKIKPYEALLVALVLTLLAFALIWPLNTLTKQLSIAAVIIAATYPYFKRFFAIPQAYLGIAFGFGIPMGFAAVQNTVPAAAWWLLVANVFWSVAYDTEYAMVDREDDLKLGMKTSAITFGRYDVAIIMFCYAMTLGIIGIVGWQFGLRIWFVAGLLLAAVCAAYHYTLIRSRERAGCFAAFNHNNWLGGAIFGGVALDYLLR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTU1_RHORT
Sequence: MSKEKFARTKPHCNVGTIGHVDHGKTSLTAAITKVLAEAGGATFQAYDQIDKAPEERARGITISTAHVEYETEARHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPALVVFLNKCDMVDDEELLELVELEVRELLTSYDFPGDDIPIVKGSALAALEDSDPKLGHDAILELMKAVDDYIPQPERPKDKPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEIEIIGIRDTQKTTCTGVEMFRKLLDQGEAGDNIGALLRGTKRDDVERGQVLAKPGSITPHTKFKCEAYILTKEEGGRHTPFFSNYRPQFYFRTTDVTGTIELPEGTEMVMPGDNIGMTVQLIAPIAMDEGLRFAIREGGRTVGAGVVASIVQ
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PD_CULPI
Sequence: LWWLFRDNLLPSVTKFVGYARTKLTVAELKEKCHPYMKVDAAHEEKYDEFWALNFYVAGSYDGRRDFELLNQEIGKFEVGKTANRLFYLRLPPSVFETVTVHIRNTCMGLKGWNRIIVEKPFGRDADSSNKLSEHLAKLFTEDQLYRIDHYLG
What is the function of this protein?
Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD, Zwischenferment.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: LEU1_SYNS9
Sequence: MAKDPGRVLIFDTTLRDGEQSPGASLNLEEKLAIAQQLARLGVDVIEAGFPFASAGDFAAVQRIAQQVGGDNGPIICGLARASKADIKACADAVAPAPRGRIHTFIATSDIHLEHKLRKSRKDVLAIVPEMVSYARSLIEDVEFSCEDAGRSDPEFLYEVIEAAIAAGATTINIPDTVGYTTPSEFGGLIAGINQHVPNIDEAVISVHGHNDLGLAVANFLEAVKNGARQLECTINGIGERAGNASLEELVMAMHVRRRYFNPFLGRKEDSPTPLTAVRTEELTKTSRLVSNLTGMVVQPNKAIVGANAFAHESGIHQDGVLKNRLTYEIIDARTVGLSDNRISLGKLSGRSAVRARLEELGYNLTREDLDEAFARFKDLADRKREITDRDLEAIVSEQVQQPEARFQLKFVQVSCGSTSRPTATVALMDEEGGERTVSAVGTGPVDAVCRALNCLADVPNDLIEFSVKSVTEGIDAIGEVTIRLRRDGSLYSGHAADTDVVVAAAMAFVNALNRLVAGQERQSLHPQKDPVVLDARPTL
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.