PharMolix/UniProtQA huggingface dataset:
Protein: JOS1_HUMAN
Sequence: MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIMNLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGKNCELLLVVPEEVEAHQSWRTDV
What is the function of this protein?
Deubiquitinates monoubiquitinated probes (in vitro).  When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme.  May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis.  May enhance membrane dynamics and cell motility independently of its catalytic activity.
What are the official names of this protein?
Josephin-1, Josephin domain-containing protein 1.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Note=Ubiquitination increases localization the plasma membrane. In the cytosol, the unubiquitinated form may be associated with the cytoskeleton via ACTB-binding.
Protein: Y568_CLOK1
Sequence: MAIFREFDVNDHHDRSLEDRRRHRQLVEKSIKDNLADIISEESIIGQSKNKKVKIPIKGIKEYQFIYGDNSSGVGSGDGSQKKGDRIGKAIKDRDGKGNQGAGNQEGEDMYEIEVTIEDVLDYLMEDLELPLMDKKKFSQILSNNSPKKSGYQRKGINPRLAKKRTVVEKLKRQQGTKRALREIHGELESDPKNKLPENTTIKSRFPFKQDDLRYFRVKRKPKLELNAAIICVMDTSGSMDSTRKFLARSFFFVLYRFIKMKYNNVEVKFISHSTSAKVVTENEFFHKVESGGTYISSGLKKALEVIEENYNPAYWNVYTFYVSDGDNWSEDNSLALKCAKDLCKVCNLFSYAEIIPSPYGSSIKHIFQNKITDNNFTVVTIHEKQDLWKSLKKILNKELEER
What are the official names of this protein?
UPF0229 protein CKR_0568.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: GPA6_DICDI
Sequence: MAFLCKSNDNTKVSMEIEKSIKDDKRTFLGITQVLLLGAGESGKSTIFKQLKILQENGLWTTKELQEFSNTIYINIITQLQVLINAAESIGIQLQPENIQLSKDYLELNHSSVTWTKEIGENSVRLWNDSGIKSTFEKRDKEFQLNDSAEYFFNNLQRVTQDNYIPTPQDALRARVTTKGIIEADVTFDNINMKIIDVGGQRSQRRKWIHCFDKVSAVIYVAGLSEYDQALREDINVNKMDESLSLFKEICNSKWFDSSSIILFLNKKDMFIEKLKRVPFKTYDKKYTGENSFEAVSLHIQRKFESVKIDPNKKIYTHFTIAVDTENIEFVFKVIKKIIVGHVMDLV
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  G alpha-6 is involved in the folic acid chemotaxis signal transduction pathway.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-6 subunit, G alpha-6.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: PGK_STRPJ
Sequence: MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEAAINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAFAGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPO_MACFA
Sequence: MGVHECPAWLWLLLSLVSLPLGLPVPGAPPRLICDSRVLERYLLEAKEAENVTMGCSESCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQAVLANSSQPFEPLQLHMDKAISGLRSITTLLRALGAQEAISLPDAASAAPLRTITADTFCKLFRVYSNFLRGKLKLYTGEACRRGDR
What is the function of this protein?
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass.  Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
What are the official names of this protein?
Erythropoietin.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSH_PARPJ
Sequence: MSIPADLKYTESHEWVRTEADGTLTVGITDHAQEALGDIVFFEVQELGKTVTAGDTVAVIESVKAASDIYAPVSGEIIEANTAVADTPDSVNSTPYESWLFKIKPAADATQDRLIDADAYTKSIGA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: TRUB_NITEU
Sequence: MLNKPSGISSNRALQISKRLLSAAKAGHTGTLDPMAQGLLPICLGEATKFSSTLLGVDKTYIASLRLGYISNTGDAEGEIRQVVGSDVNPPDFGQVTGILQTFLGRSSQIPPMFSALKQHGKPLYRYAREGITVERKAREIVIHAASLDTLSGFEMTITVRCSSGTYVRTLAEDIGKALGYGGAYLTALSRISVGHFELSQACDLDQLESETPVNRQKLLCPIDSLLNDIPSIVLDDDEALRLRQGQKIRKNMSRYGLPVNTQLKLYDDRNVFLGLGERIDPEVIVPRRMISLHEVVTGAIAGSVDLQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: XYL5_PHACH
Sequence: MAYLKVSGTKIVDKDGNEVILRGAGLGGWMNMENFITGYPGCEFQIRAALADVVGQEKSEFFFDKFLEYFFTDADAAFFKSLGLNCIRLPFNYRHFEDDMNPRVLKPEGFKHLDRVIDICAKHGIYTVLDLHTAPGGQNTDWHSDAGTHIAKFWEHKDFQDRVIWLWEELAQHYRDNTWIAGYNPLNEPTDPYQTRLIAWYDRVYAAIRKHDPHHALFLDGNTFASDFSHFGDAEKRWENTAYAIHDYSVFGFPAAPEPYVSSEAQRRRLRRSYEKKREWMDARGLCVWNGEFGPVYARREYEGDLTDSINEERYRVLKDQLEIYNKDRLSWSIWLYKDIGFQGMVHVSRDTPYMTLFRDFLAKKHRLAIDAWGADDSAVRHVYQPLIDLIKQEVKPEHQELYPAPVWKLSDRVGRLARNILVSEFLVREWAEHFRGKSTEELDAIAKSFAFENCLHRDGLNKVLTDNASLVAQGA
What is the function of this protein?
Catalyzes the hydrolysis of xylo-oligomers to xylose units and plays an important role in xylan degradation.  Can also perform the transglycosylation of xylose and alcohol.  Has no endoglucanase activity.
What are the official names of this protein?
Beta-xylosidase, 1,4-beta-D-xylan xylohydrolase, Xylan 1,4-beta-xylosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAF1D_HUMAN
Sequence: MDKSGIDSLDHVTSDAVELANRSDNSSDSSLFKTQCIPYSPKGEKRNPIRKFVRTPESVHASDSSSDSSFEPIPLTIKAIFERFKNRKKRYKKKKKRRYQPTGRPRGRPEGRRNPIYSLIDKKKQFRSRGSGFPFLESENEKNAPWRKILTFEQAVARGFFNYIEKLKYEHHLKESLKQMNVGEDLENEDFDSRRYKFLDDDGSISPIEESTAEDEDATHLEDNECDIKLAGDSFIVSSEFPVRLSVYLEEEDITEEAALSKKRATKAKNTGQRGLKM
What is the function of this protein?
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription.  The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter.  SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.  Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
What are the official names of this protein?
TATA box-binding protein-associated factor RNA polymerase I subunit D, RNA polymerase I-specific TBP-associated factor 41 kDa, TAFI41, TATA box-binding protein-associated factor 1D, TBP-associated factor 1D, Transcription initiation factor SL1/TIF-IB subunit D.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATA_MYCTU
Sequence: MGSLSPWHWAILAVVVIVLFGAKKLPDAARSLGKSLRIFKSEVRELQNENKAEASIETPTPVQSQRVDPSAASGQDSTEARPA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: IF1_CERS1
Sequence: MAKEDTLEFPGVVKELLPNATFRVELDNGHELIAVMAGKMRKNRIRVLAGDKVQVEMTPYDLSKGRINYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_ANADE
Sequence: MPKLKTKSGAKKRFVPKKSGKVKFRRAGVRHLATFGKTKKQKRHLRGTDHLAPMDEKKIKECFPYAR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PSTS_HAEIN
Sequence: MKKKSYYVLTLGTLPFAQANSITGAGASFPYPIYAKWASLYEKETGNKVNYQSIGSGGGQQQIIAKTVDFGASDDPMKSELLQQHQLVQFPAVIGGIVPVVNLPEIKPGKLKLSGKLLAEIFLGKIKKWNDPDLVALNPTLPLPNKNIIVIHRSDGSGTTFGFTNYLSKISNDWKNQVGEGKSVKWLTGQGGKGNEGVASYVRQMKYSIGYVEYAYAKQNQLAWISLQNQAGQFVQPSNESFMAAASHAKWHEKAGMGVILTNETGEKSWPITAASFILLNKYSDNPETTKNVLAFFDWAFSRGQDAATELDYVPIPADVVSTIKSQWKTELKQ
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HEMA_I76A6
Sequence: MKTIIALSYIFCLVFAQDLPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKICDNPHRILDGINCTLIDALLGDPHCDGFQNEKWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINEGFNWTGVTQNGGSRACKRGPDNGFFSRLNWLYKSGSTYPVQNVTMPNNDNSDKLYIWGVHHPSTDKEQTDLYVQASGKVTVSTKRSQQTVIPNVGSRPWVRGLSSRVSIYWTIVKPGDILVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: SYY_NEIG2
Sequence: MSVIQDLQSRGLIAQTTDIEALDALLNEQKIALYCGFDPTADSLHIGHLLPVLALRRFQQAGHTPIALVGGATGMIGDPSFKAAERSLNSAETVAGWVGSIRSQLTPFLSFEGGNAAIMANNADWFGSMNCLDFLRDIGKHFSVNAMLNKESVKQRIDRDGAGISFTEFAYSLLQGYDFAELNKRHGAVLEIGGSDQWGNITAGIDLTRRLNQKQVFGLTLPLVTKSDGTKFGKTEGGAVWLNAKKTSPYQFYQFWLKVADADVYKFLKYFTFLSIEEIGVVEAKDKASGSKPEAQRILAEEMTRLIHGEEALAAAQRISESLFAEDQSRLTESDFEQLALDGLPAFEVSDGINAVEALVKTGLAASNKEARGFVNAKAVLLNGKPAEANNPNHAAERPDDAYLLIGEYKRFGKYTILRRGKRNHALLVWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_BARQU
Sequence: MNHPDIAQRVYNHTWKLDPIIRSLLDTDFYKLLMLQMIWGLYPNVNVTFTLINRTKTIRLADDIDEGELRAQLDHALSLRFTKKEMIWLAGNTFYGRKQIFKPDFLHWLKNFQLPEYELTRKDGQYILHFHGPWSHSSMWEIPALAIISELRSRAAMKNLDRFALDVLYARAKAKMWSKVEQLKKLPDIKISDFGTRRRHSFLWQRWCVEALKEGIGDSFTGTSNVLLAMATDLEALGTNAHELPMVIAALTNNDNELCKAPYQVLQDWNRYYGGNLLIVLPDTFGTETFLRNAPDWVADWTGFRPDSAPPIEGGERIIQWWKEKGKDPREKLLIFSDALDVNTIEQTYHHFHGRVRMSFGWGTDLTNDFVGCAPQKIATFDALSLVCKVTHANGRPAVKLSDNPEKTIGDPREIQRYLNFFGNENFITRPINT
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: FTHS_STAAN
Sequence: MTHLSDLDIANQSTLQPIKDIAASVGISEDALEPYGHYKAKIDINKITPRENKGKVVLVTAMSPTPAGEGKSTVTVGLADAFHELNKNVMVALREPALGPTFGIKGGATGGGYAQVLPMEDINLHFNGDFHAITTANNALSAFIDNHIHQGNELGIDQRRIEWKRVLDMNDRALRHVNVGLGGPTNGVPREDGFNITVASEIMAILCLSRSIKDLKDKISRITIGYTRDRKPVTVADLKVQGALAMILKDAIKPNLVQSIEGTPALVHGGPFANIAHGCNSILATETARDLADIVVTEAGFGSDLGAEKFMDIKAREAGFDLAAVVVVATIRALKMHGGVAKDNLKEENVEAVKAGIVNLERHVNNIKKFGVEPVVAINAFIHDTDAEVEYVKSWAKENNVRIALTEVWEKGGKGGVDLANEVLEVIDQPNSFKPLYELELPLEQKIEKIVTEIYGGSKVTFSSKAQKQLKQFKENGWDNYPVCMAKTQYSFSDDQTLLGAPSGFEITIRELEAKTGAGFIVALTGAIMTMPGLPKKPAALNMDVTDDGHAIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: FPG_MYCSJ
Sequence: MPELPEVEVVRRGLDAHVTGKAITAVRVHHPRAVRRHEAGPADLTARLLGMRITGTGRRGKYLWLTLDGGDEPLARRAESSVALVVHLGMSGQMLLGPIPKEDHLRIAALLDDGTALSFVDQRTFGGWLLADLVTVDGTDVPVPVAHVARDPLDPRFDRDAVVKVLRGKHSEIKRQLLDQTVVSGIGNIYADEALWRAKVNGARLAESLTKPKLAEILDHAADVMRDALGQGGTSFDSLYVNVNGESGYFDRSLDAYGREGEPCRRCGAIMRREKFMNRSSFYCPRCQPRPRVRRA
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL4_RICB8
Sequence: MKTKILNLANEEIGEISLNEDIFAVEFIRDDIIKQVVDWQRAKAMAGTHKTKTVSEVSGTTKKPFKQKGTGNARQGSLRSVQMRGGGVIHGPVVRSHATKLPKKVRKLGLIHALSEKFSEGKLLVIDSLKLETPKTSNLVNILNKFQGKSFFVIDGNEVDVNFSLAAQNIYNTVVVPQIGANVYDIIRHEYVLLSQEAVNVLEERLK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: COAA_STRPI
Sequence: MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIKNGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWISINLTNLQNYIEPTRNRAEVILHKSKNHEIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_STAAW
Sequence: MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGEALKKYHQMRGE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: MTOX_ECOL5
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQMLWDELSRHNEDDPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: SYP_CHLL2
Sequence: MADKITSRSQDYSQWYIDLVRSAKLADYSDVRGCMVIRPNGYAIWEKMQAALDAMFKETGHVNAYFPLFIPESYIAKEAEHIEGFAPECAVVTHGGGEELAEKLYVRPTSETIIWASYKKWIQSYRDLPILINQWANVVRWEMRTRLFLRTTEFLWQEGHTAHATKEEASEEVLRMITIYKKFAEEYMALPVIMGRKTESEKFAGADETFCIEAMMQDGKALQAGTSHHLGQNFAKAFDCQFQTSAGELDFVWATSWGVSTRLIGALIMAHSDDRGLVLPPKLASRQVVVIPILRGDKTAVLEQADAIVCTLKKHGIPAFVDSSDQNSPGWKFAEYELQGIPLRIELGPRDLAGKKCVVARRDTLEKTELPLDDTFSMQVSEILNSIQQNLYDRALSFRNEKTVEVKSYEEFKTAVENGFVIAHWDGTDETESKIKEETKATIRVLPEEQEYLDRYTMMEPGVCIYSGRPAARKVVFAKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_METJA
Sequence: MKKVEPVNFRELDKKIKKFWEENDIYQKVKKKNERNKEFYFVDGPPYCSGAIHLGTAWNKIIKDTYLRFKRMQGYNVLDKAGWDMHGLPIEVKVENEFGIKNKKEIETKIGVKQFIEKCKEFALKHKEIMEKQFKNLGVWLDWENAYMPITKEYMEIGWWTLKVAHEKGLLTRDLRVVYWCPRCETALAEHEVRGEYKEVYDPSVYVKFRLANEENTYIVIWTTTPWTLVANLAVTVHPDYDYAYVEVEFDDKKEVWIIAEKLVEEVINKAKKFHNIKNYKIIKKVKGKELEGIKYIHPLLEENERQKEFAELENAHTVILGEHVTLEGGTGLVHTAPGHGEEDFEVGKKYNLPIYSPIDDEGKYVEGKWKGVFVKDADAEIIETLKNKGLLVYAGKIKHSYPHCWRCKTPLLFRATEQWFLEISKIKDNIIEHAKTVQWIPHWVETRYINGVKFVGDWNISRQRYWGIPIPVWVCEKCGKYIVVGSVEELEEKMINKDEVGEINDLHKPTVDKIKLRCECGGEMKRVPDVLDVWFDSGLAPYASIGVKELKKADFITEGHDQVTKWFYSQHALSAIVFNDIPYKKCLMHGFTLDEHGDKMSKSLGNVVNPDDVVEKYGADLLRFYLLSANKVWEDLRFVWSEMDDVLSLFNTLWNAYMFAVNYMVLDNFKPDEKYFEYLKDEDRWIVSRINSVAKIAIENLEVPYFHTYTWTLKDFILNDLSRWYIRLIRDRTWKEKDDADKLAAYQTLYYVLLKLATILAPVAPHTAEAIYQNLKTEDMEESIFMNKIEVDEEFIDEELERDMAIVRDVVDAIYRGRDRIKYTLRYPLKEITIAGGEEVKKAVERFEYIIKEQGNVKNIKFGEVEGSKYIIKPNYRELGKRYRSEVPKVVEALNKADAKELMERLKEGAVILDGYEIKPEYVEIRLEIPEHIAGVEFSKGTVFINTEITDDLIKEGLMREVIRRIQAMRKDMDLDIEEKIKIKVEGIDLDEFKEIIEREVRGQFVDEIKADYEKDWEIKTPNGEKYNVKIAIERINK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CR021_RAT
Sequence: MRQKYYIEAAARGLVGSCPGQARYLLWAYSSTHEDNSTFQETCPHCFQLLVLDNSRVRLKPKAKLTPKIQKLLNREARNYTLSFKETKLLRKYRDSASVLLITCRTCNRTVRHHGKSRSFLSALRSSRAASAASKASPKTPKRAAAGSTNISQSVHGSKGRSPSSTVRTPTSGQSTPICSSRNGSKRKKHFSQLKALLSQSASDKNPTLDFRHFLSSL
What are the official names of this protein?
UPF0711 protein C18orf21 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0711 family.
Protein: PTMCB_STRPN
Sequence: MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGYLPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGAMVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLTGAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFLLEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAMAGGISGTFTFQLLDAGLKSPASPGSIIAIIATAPKGVWPHLNVLLGVLVAAVVSFLVAALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMGSSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHVSVDNFLASSRYDEIVASLTGASPIAEIEGDIPTSAPVDSQESDLNHIDAVVVAYGKAQGTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNSQFLIVDSLVTTPEYDKMAARMYK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METXA_DESPS
Sequence: MEKEIKDHKSVGIVEKQFFTCAQVPSPLILENGAKLGPITIAYETYGNLSARKDNAILINHAFSGDSHVAGHYATDGPKEKPGWWDFLVGPGKGIDTDKYFIICSNILGSCNGTTGPASKNSETGEAYALDFPMVTIGDMVATQKLLIDHLGIPKLLAVIGGSVGGMQTLEWAIRYPEMMHSVIPIATTMRHSALAIAFNEIARQAIMTDPHWNRGKYYGQAHPDTGLAVARMVGHVTYLSDEAMRRKFGRNLQEKENLSYGFDADFQVESYLRYQGNKFVHRFDANSLLYITKASDYFDIVERISTSGPETELTAPQQKYLVISYSSDWLYPTYQARDLVKALKRSGRNVSFSEIESDCGHDAFLIPDDRLEQLMRGFLAGIYTGIAEI
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_UREPA
Sequence: MSFEKYKTIIQKYNQIFNLTRLDSDDKIYQNFFLDSLAPYKELDFFTQNTNLKLIDIGSGSGIPGVVLKIIFKNLNLTLLEANQKRCEFLKILTQELGLNDVLIWNMRAEDLTQSMRESFDIATSRAVASLDKILEISAAFVKVNGYLIQPKSIKFYEEELKAKNIIKTLYLERIALKDFWENDYHHLVGVYLKKQITPLQFPRPWNLILKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.