PharMolix/UniProtQA huggingface dataset:
Protein: GATA_RAT
Sequence: MLGRTLREVSSALKQGHITPTELCKKCLSLIKKTKYLNAYITVSEEVALKQAEESEKRYKQGQSLGDLDGIPVAVKDNFSTSGIETTCASNMLKGYLPPYNATVVQRLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWTYSKQYRERSRQDAQEDSHWLITGGSSGGSAAAVAAFTCFAALGSDTGGSTRNPAAHCGTVGFKPSYGLVSRHGLIPLVNSMDVPGIFTRCVDDTAIVLGVLAGHDPKDSTTVNDPVKPTTLPSVPDVSGLCIGIPKEYLVPELSSEIRSLWSQAADLFEAEGARVIEVCLPHTCYSIVCYHVLCTSEVASNMARFDGLQYGHRSAVDMSSTEALYAATRQEGFNDVVKGRILSGNFFLLKENYENYFVKAQKVRRLIVNDFVNVFGSGVDVLLTPTTLTQAVPYLEFIKEDNRTRSAQDDIFTQAVNMAGLPAVNVPVALSSQGLPIGLQLIGRAFCDQQLLTVAKWFEKQVQFPVIQLQDLMDDGSLVPENGKLTSGSLTQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A, Glutaminyl-tRNA synthase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VG50_ICHVA
Sequence: MELLVVTLTCLGMSLLASNLALVGVVRSYTNETPTPGPETELITTTVARMTDPTAKPSDFPGDAVTGTQPVPREPSSLPRTTPSLAHTTISKMISLGTRPRPTIPGVPTTIPNTDAPVDPGSVHTTARVVTDITTKQTPTTPATPAGANDTANITTATPAGANDTANITTATPAGANDTANITTATPAGANDTAVTTTSATPAGANDTAVTTTPATPAGANDTANGTVVTTTPAMPAGANDTANGTAVTTTPAMPAGANDTANITTATPTGANDTANVTMPAGATDTVVTTTPAMPTGANDTANITTATPAGANDTANVTMPAGATDTVVTTTPAMPAGANDTANVTKPAGSTDTVVTTTPAMPTGATDTVVTTTPAMPTGATDTVVTTTPAMPTGATDTVVTTTPAKPAGANGTVVTTTPAMPAGANDTVVTTAPATPAGANDTANVTKPTGATDTVVTTATVKPTGATGTVTTTTAKPTGANDTANVTKPTGATGTVTTTTAKPTGATGTVTVATAKPTGATGTVTTTTAKPTGANGTVTTTTAKPTGATGTVTTTTAKPTGANGTVTTTTAKPAGANGTVTTTTAKPAGANGTVTTTTAKPAGANGTVTTTTAKPAGANGTVTTTTAKPAGAGHGHGHGHGHGHGHGHGHGGRGPPGGHKPKSGARR
What are the official names of this protein?
Uncharacterized protein ORF50.
Protein: MARH2_RAT
Sequence: MTTGDCCHLPGSLCDCSSSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRALDTPSDCPFCRICHEGANGENLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKRTLCCDMVCFVFITPLAAISGWLCLRGAQDHLRLHSRLEAVGLIALTIALFTIYVLWTLVSFRYHCQLYSEWRKTNQKVRLKIREADGSEDPHHSLLATGLLKKVAEETPV
What is the function of this protein?
E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.  Together with GOPC/CAL mediates the ubiquitination and lysosomal degradation of CFTR (By similarity).  Ubiquitinates and therefore mediates the degradation of DLG1 (By similarity).  Regulates the intracellular trafficking and secretion of alpha1-antitrypsin/SERPINA1 and HP/haptoglobin via ubiquitination and degradation of the cargo receptor ERGIC3 (By similarity).  Negatively regulates the antiviral and antibacterial immune response by repression of the NF-kB and type 1 IFN signaling pathways, via MARCHF2-mediated K48-linked polyubiquitination of IKBKG/NEMO, resulting in its proteosomal degradation (By similarity).  May be involved in endosomal trafficking through interaction with STX6.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF2, Membrane-associated RING finger protein 2, Membrane-associated RING-CH protein II, MARCH-II, RING finger protein 172, RNF172, RING-type E3 ubiquitin transferase MARCHF2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi- pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasm. Cell membrane; Multi-pass membrane protein.
Protein: IL1B_RABIT
Sequence: MATVPELTSEMMAYHSGNENDLFFEADGPNYMKSCFQDLDLCCPDEGIQLRISCQPYNKSFRQVLSVVVALEKLRQKAVPCPQAFQDDGLRTFFSLIFEEEPVLCNTWDDYSLECDAVRSLHCRLQDAQQKSLVLSGTYELKALHLNAENLNQQVVFSMSFVQGEESNDKIPVALGLRGKNLYLSCVMKDDKPTLQLESVDPNRYPKKKMEKRFVFNKIEIKDKLEFESAQFPNWYISTSQTEYMPVFLGNNSGGQDLIDFSMEFVSS
What is the function of this protein?
Potent pro-inflammatory cytokine.  Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.  Promotes Th17 differentiation of T-cells.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.  Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-1 beta, IL-1 beta, Lymphocyte proliferation-potentiating factor.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted. Lysosome. Secreted, extracellular exosome. Note=The precursor is cytosolic. In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.
Protein: FKB1A_XENLA
Sequence: MGVQVETITEGDGRTFPKKGQTVVVHYVGSLENGKKFDSSRDRNKPFKFIIGRCEVIRGWEEGVAQMSVGQRARLTCSPDFAYGATGHPGIIPPNATLTFDVELLRLE
What is the function of this protein?
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand.  May modulate the RYR1 calcium channel activity.  PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA2_RHOGU
Sequence: MKHVAAYLLLVSAGNTSPSAEDVKKVLAAADIQADEERLSVLIKELEGKDVNEVIAEGSKKLASVPSGGAAPAAAAGGAAAGGAAEEKAEDKPAEKDEESDDDMGFGLFD
What is the function of this protein?
Probable bifunctional protein.  The phosphorylated protein plays an important role in the elongation step of protein synthesis (By similarity).  The phosphopantetheinylated protein acts as an acyl carrier protein.
What are the official names of this protein?
60S acidic ribosomal protein P2, Acyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_DEIRA
Sequence: MSIVILDFGSQFTRLITRRFRELGAYSVILPGTASLERIQQENPQGIVLSGGPSSVYDEGAPRPAPGVLDLNVPILGVCYGMQYLAHEAGGDVKRAGKREYGKADLTEYGGRLFEGIQGEFVAWMSHSDSVTQLPQGYQVVARTEHTPVTAIENNDTRRYGVQFHPEVVHTPKGGQMLANFLDICGVTRDWNAEHIVDELIEGVRAQVGDTGRVLLGISGGVDSSTLALLLAKAVGERLTAVFIDHGLLRLGEREQVEAALTPLGVNLVTVDAKDEFLGQLAGVSDPEQKRKIIGREFIRAFERETAKLGDFEFLAQGTLYPDVIESAGGEGAANIKSHHNVGGLPDDVQFKLVEPFRTLFKDEVREIARLLGLPDHIRMRHPFPGPGLAIRCLGEVTAEKVDILQRVDDIFISGLREFGLYDGCSQALAVLTPIQSVGVMGDERTYSYTAALRAVTTDDFMTAEWARLPYDFLATMSNRIVNQVHEINRVVYDITGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GVPA1_HALSA
Sequence: MAQPDSSGLAEVLDRVLDKGVVVDVWARVSLVGIEILTVEARVVAASVDTFLHYAEEIAKIEQAELTAGAEAAPEA
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  GvpA type proteins form the essential core of the structure.
What are the official names of this protein?
Gas vesicle structural protein 1, GVP, P-VAC.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: PYRH_GEOKA
Sequence: MEQPKYKRVVLKLSGEALAGKQGFGIQPAVIQSIAKQVKEVVELGVEVAIVVGGGNIWRGKTGSEMGMDRATADYMGMLATVMNALALQDSLEQLGVETRVQTSIEMRQVAEPYIRRRAIRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYSADPNVDANAVKYDELSYLDVIKQGLGVMDSTASSLCMDNNIPLIVFSIMEEGNIKRAVLGENIGTIVRGK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_STRP7
Sequence: MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNERLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKLGKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITDYKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQEAAKNAVEKGLDSCI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEP1A_DANRE
Sequence: MICPRKKRPIKDEDFSAIVVPSMRGHGYLDYTVESHPSKALQNMDELRHHEMLCDLVLHVTYKDKIVDFKVHKLVLAASSPYFKAMFTSNFKECHASEVTLRDVCPQVISRLIDFAYTSRITVGETCVLHVLLTAMRYQMEEVAKACCDFLMKNLEPSNVIGISRFAEEIGCTDLHLRTREYINTHFNEVTKEEEFFSLSHCQLLELISQDSLKVLCESEVYKACIDWVRWDAESRAQYFHALLNAVHIYALPPTFLKRQLQSCPILSKANSCKDFLSKIFHEMALRKPLPPTPHRGTQLIYIAGGYKQHSLDTLEAFDPHKNVWLKLGSMMSPCSGLGACVLFGLLYTVGGRNLSLQNNTESGSLSCYNPMTNQWTQLAPLNTPRNRVGVGVIDGSIYAVGGSHASTHHNSVERYDPETNRWTFVAPMSVARLGAGVAACGGCLYVVGGFDGDNRWNTVERYQPDTNTWQHVAPMNTVRSGLGVVCMDNYLYAVGGYDGQTQLKTMERYNITRDVWEPMASMNHCRSAHGVSVYQCKIFVLGGFNQGGFLSSVECYCPASNVWTLVTDMPVGRSGMGVAVTMEPCPGILPEEEEEVDEEM
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination (PubMed:18057000).  Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes (PubMed:18057000).  In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine residues in KEAP1, leading to inactivate the ubiquitin ligase activity of the BCR(KEAP1) complex, promoting nfe2l2/nrf2 nuclear accumulation and expression of phase II detoxifying enzymes (By similarity).
What are the official names of this protein?
Kelch-like ECH-associated protein 1A.
What is the protein family that this protein belongs to?
Belongs to the KEAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic.
Protein: VKT16_DRYCN
Sequence: MSSGGLLLLLGLLTLWAELTPVSSKDRPDFCHLPADSGSCKGNFQAFYYHPVHRTCLEFIYGGCEGNANNFKTMDECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor 161, SPI-161.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: NTPP_STRCO
Sequence: MTPQPRRRLVLASQSPARLGLLRQAGLAPEVLVSGVDEEAVTAPTPAELALALAEAKASVVAAKPEVHGALVIGCDSVLDLDGQALGKPADAEEATARWKAMRGRAGTLQTGHCVWDTASGRHVSATASTVVRFGEPTDDEIAAYVASGEPLHVAGAFTLDGRSAPFIDGIDGDHGNVIGLSLPLLRRLLADLGTGITELWAPAED
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_ACICJ
Sequence: MADPSGSHLRAVILAGGAGRRLGGVDKALLILHGRTMLDHAIATVSGQVGAVALSAAGDPARFARFGIPVLEDGRHRGKGPLAGVLAGMRWAAASGGETLLSLPVDTPFAPRDLAARLGAAPAVAASHGRTHHLVALWPVAAADALERFLDGPGPYRVSGFAAEIGMRAVAFADERDPFVNINTQADLDAAEAGRC
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_RUEST
Sequence: MKDLENIPALMEDIGKRAKAAAQQLATASAAQKEQALNAAADAVWAQRGEIIAANAKDLEFGRDKGLSSAMMDRLMLDEARIQGIVDGLRAVAAQADPVGAVLDEWTQPSGLRIQRVRTPLGVIGVIYESRPNVTADAGALCLKSGNAVILRGGSESLHSAQAIHGCLAAGLRAADLPEDAVQLVPTRDRAAVQELLTMTAYVDVIVPRGGKGLVGLVQREARVPVFAHLEGIVHIYLDKDADRKKAIDVVLNAKTRRTGICGAAECLLIHEDIADSIGKDVLDLLAMGGVEIHAEEGLPGPDSMQVATSEDWGKEYLDAIIAAKKVASIDEAIAHIRRYHSAHTDCIITENDAAVAQFFSELDSAILMHNASTQFADGGEFGMGAEIGIATGKMHARGPVGATQLTSFKYLVRGDGTVRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_NEIMF
Sequence: MDTPVYLYTDGACKGNPGAGGWGVLMRYGSHEKELFGGEAQTTNNRMELTAVIEGLKSLKRRCTVIICTDSQYVKNGMENWIHGWKRNGWKTAAKQPVKNDDLWKELDTLVGQHQVSWTWVKGHAGHAENERADDLANRGAAQFS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_XYLF2
Sequence: MIKKTILNDTHQALGAKMVDFSGWEMPIHYGSQIDEHHHVRRNAGIFDVSHMTVIDLHGTQVRPLLRRLLANSVDKLKVPGKALYSCMLNPQGGVIDDLIVYYLREDYFRFIVNAATREKDLAWINTQASAFNVRVEERADLAMLAVQGPAARAQVTNLLAETHRDAVEKLGRFAALEVASHSKKPLFISRTGYTGEDGFEILLPQEETITLWNALLKTGVKPIGLGARDTLRLEAGMNLYGQDMDEQVSPYEAALGWTVMLDEGRNFIGRNVLEQQKTNGVSRQMIGLLMDEKGVLRHGQKVLTAQGEGHILSGTFSPTLNKAIGFARVPAGKPSEVRVNIRDREIPVRVVKFPFVREGQTQPNIFD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RPP1_ARATH
Sequence: MGSVMSLGCSKRKATNQDVDSESRKRRKICSTNDAENCRFIQDESSWKHPWSLCANRVISVAAVALTNFRFQQDNQESNSSSLSLPSPATSVSRNWKHDVFPSFHGADVRRTFLSHIMESFRRKGIDTFIDNNIERSKSIGPELKEAIKGSKIAIVLLSRKYASSSWCLDELAEIMKCRQMVGQIVMTIFYEVDPTDIKKQTGEFGKAFTKTCRGKPKEQVERWRKALEDVATIAGYHSHSWRNEADMIEKISTDVSNMLNSFTPSRDFDGLVGMRAHMDMLEQLLRLDLDEVRMIGIWGPPGIGKTTIARFLFNQVSDRFQLSAIMVNIKGCYPRPCFDEYSAQLQLQNQMLSQMINHKDIMISHLGVAQERLRDKKVFLVLDEVDQLGQLDALAKETRWFGPGSRIIITTEDLGVLKAHGINHVYKVEYPSNDEAFQIFCMNAFGQKQPHEGFDEIAWEVTCLAGELPLGLKVLGSALRGKSKREWERTLPRLKTSLDGKIGSIIQFSYDVLCDEDKYLFLYIACLFNGESTTKVKELLGKFLDVKQGLHLLAQKSLISFDGERIHMHTLLEQFGRETSRKQFVHHGFTKRQLLVGARGICEVLDDDTTDSRRFIGIHLELSNTEEELNISEKVLERVHDFHFVRIDASFQPERLQLALQDLIYHSPKIRSLNWYGYESLCLPSTFNPEFLVELDMRSSNLRKLWEGTKQLRNLKWMDLSYSSYLKELPNLSTATNLEELKLRNCSSLVELPSSIEKLTSLQILDLENCSSLEKLPAIENATKLRELKLQNCSSLIELPLSIGTATNLKQLNISGCSSLVKLPSSIGDITDLEVFDLSNCSSLVTLPSSIGNLQNLCKLIMRGCSKLEALPININLKSLDTLNLTDCSQLKSFPEISTHISELRLKGTAIKEVPLSIMSWSPLADFQISYFESLMEFPHAFDIITKLHLSKDIQEVPPWVKRMSRLRDLSLNNCNNLVSLPQLSDSLDYIYADNCKSLERLDCCFNNPEIRLYFPKCFKLNQEARDLIMHTCIDAMFPGTQVPACFIHRATSGDSLKIKLKESPLPTTLRFKACIMLVKVNEELMSYDQTPMIVDIVIRDEHNDLKEKIYPSIYPSIYPLLTEHIYTFELDVEEVTSTELVFEFPQLNKRNWKIGECGILQRETRSLRRSSSPDLSPESSRVSSYDHCLRGD
What is the function of this protein?
TIR-NB-LRR receptor-like protein that confers resistance to the pathogen Hyaloperonospora arabidopsis (By similarity).  Probably acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792, PubMed:31439793).
What are the official names of this protein?
Probable disease resistance protein RPP1, Probable NAD(+) hydrolase RPP1, Protein RECOGNITION OF PERONOSPORA PARASITICA 1.
What is the protein family that this protein belongs to?
Belongs to the disease resistance TIR-NB-LRR family.
Protein: SMOK_CERSP
Sequence: MGKITLRNVQKRFGEAVVIPSLDLDIEDGEFVVFVGPSGCGKSTLLRLIAGLEDVSDGQIMIDGRDATEMPPAKRGLAMVFQSYALYPHMTVKKNIAFPLRMAKMEPQEIERRVSNAAKILNLTNYLDRRPGQLSGGQRQRVAIGRAIVREPAAFLFDEPLSNLDAALRVNMRLEITELHQSLETTMIYVTHDQVEAMTMADKIVVLNAGRIEQVGSPLTLYRNPANLFVAGFIGSPKMNLIEGPEAAKHGATTIGIRPEHIDLSREAGAWEGEVGVSEHLGSDTFLHVHVAGMPTLTVRTGGEFGVHHGDRVWLTPQADKIHRFGADGKAL
What are the official names of this protein?
ATP-binding transport protein SmoK, Protein PolK.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: ATPL_SYNP2
Sequence: MDSLTAAASVIAAALAVGLAAIGPGIGQGNAAGSAAEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALVLLFANPFA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SYS_BURL3
Sequence: MLDIQLLRKDLDGVAQRLADRGYTLDVAAFSALEAERRAIQTRTEELQARRNSLSKQIGAMKGKGEDTSAVMAEVGGIGDEMKAGEAKLGEIQARLSDLMLGMPNVAHESVPVGKDEADNVEARRWGTPRQFDFEVKDHVDVGTPLGLDFETGAKLAGARFTMLRGSIARLHRALAQFMIDTHTLQHGYTETYTPYIVNPEILYGTGQLPKFADDMFRVEKGGEENKVTQYLISTSEISLTNTVRESIVDASALPIKLTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQVVAPEASYAALDEMVGHAEAILQKLGLPYRVITLCTGDMGFSAAKTFDLEVWLPAQNTYREISSCSNTEAFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVAVLENYQNADGSVTVPEALRPYMGGIERIDAPAQAS
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H31_ARATH
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRFRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVAALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.1.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localized at chromocenters.
Protein: RL33_KLEP3
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKMELKKYDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: KTHY_CAMJE
Sequence: MYVVFEGIDCVGKSTQISLLKEIYKDAIFTLEPGGTELGKHLREILLNKTHPINKRAELLLFLADRAQHFEEILKTNQNKLIISDRSFISGMAYAKDFENDLLFALNSFALENFFPQKIIFLKGDANLIQERLSQKELDSIEKRGIEYFLSVQDKLEKVLHFLKEKISVEILTLDAKESKEKLHQQIKEFLQ
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ASSY_SYNSC
Sequence: MGRAKKVVLAYSGGVDTSVCIPYLKQEWGVEDVITFAADLGQGDELEPIRQKALDAGASQSLVGDLIEPFIKDFAFPAIRANALYEGRYPLSTALARPLIAKRLVEVAREVGADAVAHGCTGKGNDQVRFDVAIAALAPDLKVLTPAREWGMSREETIAYGERFGLPAPVSKKSPYSIDLNLLGRSIEAGPLEDPMVAPPEEVFAMTRSVEAAPDASEEIEIAFEAGNPVGINGQKLDPVALIREANRLAGIHGIGRLDMIENRVVGIKSREIYETPGLLLFIQAHQELESLTLAADVLRSKRQLEMQWADLVYQGLWFGPLKDALDGFMDRTQATVNGVVRLRLHKGTATVTGRGSADSSLYVPEMASYGSEDQFDHRAAEGFIYVWGLPTRLWSASQRRSS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD_HAHCH
Sequence: MSSPVLKCQSVHKVYVQGKESIEVLRGVNIALYPEQTVAIVGASGSGKSTLLNIMGALDHPSSGSISISGQDVSDMDEKAKARLRNAHVGFVYQFHHLLPEFSALENVCMPLLLRGVAVKEAKKEAEYWLGRVGLSHRLKHRPGQLSGGERQRVAIARALSPRPSCVLMDEPTGNLDPETAESVQALLWDLVRQNQTSFVLVTHDYRLAARMDEQYSLEEGVLAKVAPNSL
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.