PharMolix/UniProtQA huggingface dataset:
Protein: ZFP8_ARATH
Sequence: MDETNGRRETHDFMNVNVESFSQLPFIRRTPPKEKAAIIRLFGQELVGDNSDNLSAEPSDHQTTTKNDESSENIKDKDKEKDKDKDKDNNNNRRFECHYCFRNFPTSQALGGHQNAHKRERQHAKRGSMTSYLHHHQPHDPHHIYGFLNNHHHRHYPSWTTEARSYYGGGGHQTPSYYSRNTLAPPSSNPPTINGSPLGLWRVPPSTSTNTIQGVYSSSPASAFRSHEQETNKEPNNWPYRLMKPNVQDHVSLDLHL
What is the function of this protein?
Probable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin and cytokinin.  Is not involved in the regulation of trichome branching.  Is functionally equivalent to GIS2 (PubMed:17507408).  Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development (PubMed:24808098).
What are the official names of this protein?
Zinc finger protein 8.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRY_SMIMA
Sequence: MCSFLDVEVKDRFVEGDFGMSEMVKSNLANCSSRVKRPMNAFMVWSQTQRRKVALQNPKMHNSEISKQLGVTWKLLSDSEKRPFIDEAKRLRDKHKQVSDYKYQPRRKTKSFLKNVYNHKDHLTKATDQLIKTQHLKEDSTTIYENTMKCPEISSFYCAQESTYLDNWMNLPPEQENTEFWQGLFTNETETCRSLPHGQMDCNECRSI
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: THIG_CLOTE
Sequence: MDKLNIGGKQLESRLFIGTGKYGSNEILPKVIESSKSQVITVALRRVDLNSREENILNYIKDDCVLLPNTSGARNAEEAVRLARLSKAAGCGNWIKIEAISDNKYLLPDNYETIKATEILAKEGFYVFPYMNPDLMDAKRFVAAGAAAVMPLGAPIGTNKGLKTEEMIKILIEEIKEVPIIVDAGIGKPSDACKAMEMGADAVLLNTAIATAENPILMGEAFKNAVEAGRKAYLAGFGTEAKFANASSPLIGFLR
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_PARP8
Sequence: MSWLDKLLPPKIKQTDPKSRKGIPEGLWIKCPSCEAVLYRNDVEANLHVCPKCDHHMRIGARERLDGLLDPEGRYEIGQEILPVDALKFKDSRKYPDRLKEAMDETDETDAMVVMGGAIHTLPVVVACFEFAFMGGSMGSVVGERFARGAQNALEQNVPFICFTASGGARMQESLLSLMQMAKTTAMLTKLSEAKLPFISVLTDPTMGGVSASFAFLGDVVIAEPKALIGFAGPRVIEQTVREKLPEGFQRAEFLLQKGAIDMIVDRRKLREELAQLMALLTRQPADAVA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCC1_BOVIN
Sequence: MLYSLLLCECLWLITAYAHDDEWIDPTDMLNYDAASGRMRKSQVKYGISEKEEVNPDLSCANELSECYNRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETKKLGLPDENKHDMHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILINFKFHDFETWKWRFEEFFGVDPYNVFMVLLCLLCIVALVATELWTYVRWYTQLKRVFFISFLISLGWNWMYLYKLAFAQHQAEVAKMEPLNNVCAEKMNWSGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGAGEFIKALMKEIPVLLHIPVLIIMALAVLSFCYGAGKSVNMLRHVGGPEREAPQALQAGERRRQQKIDYRPHGGAGDADFYYRGQISPIEQGPNDNTYEGRRDVLRERDVGLRFQTGNKSPEVLRPFDLQEAEAREHPKVVPGLKSPNLESKPREMGEIPGESTPTESSTESSQPAKPVSGQKVSEGVEGCPAVEKAQLRTDAAGGPEEGSTCSPASTAVEVCG
What is the function of this protein?
Seems to act as a chloride ion channel (By similarity).  Plays a role in retina development (By similarity).
What are the official names of this protein?
Chloride channel CLIC-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the chloride channel MCLC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes.
Protein: SAPK5_ORYSJ
Sequence: MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGNRIDENVFREIVNHRSLRHPNIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHVSQPCRHLLSRIFVANPYKRISMGEIKSHPWFLKNLPRELKEEAQAVYYNRRGADHAASSASSAAAAAAFSPQSVEDIMRIVQEAQTVPKPDKPVSGYGWGTDDDDDDQQPAEEEDEEDDYDRTVREVHASVDLDMSNLQIS
What is the function of this protein?
May play a role in signal transduction of hyperosmotic response.
What are the official names of this protein?
Serine/threonine-protein kinase SAPK5, Osmotic stress/abscisic acid-activated protein kinase 5, RK3 kinase, stress-activated protein kinase 5, OsSAPK5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GIP1_ARATH
Sequence: MSRISGDGGSRVSIPADLLQTIQNIREVTGKQHSDEDIFSVFKECFSDPHETTQKLLYLDTFHEVRSKRERKKENLVPNTQGRGRTGRKNFASSYTDASNGRSAAFKKQSGANHIIGGSGTASSAPNNARNDTKPSSIMAPNPISLPSGISNQKIQDAIISPVDKVDTEEQPLSKATSSSKDVVEPDKSKESSVSVAVSDSVVENDTQYAVVETFQIPQQSERVIKSEVAASKCKNESLLKSDVGERPHVTFPVHIQVAKMLENGLTFGSFDSNFVREASSDKFTIGCDDSNIESSHGTAASARKDISTFSQDKNHEISNSAAQNELTLQPDQTVLPEEGSEGDKVKNEVLPITDTHQAAKCDAPPISYPDQYSLAAAQQAMHLYRQQYSLNYFPYGPYFPPYYMPQPYIHQYLSPNGFQQQSYLPPGDDAPAPPGAELPLTHIKPGSDIGNSPPTTIPFSYTSYAFNHIPSAATINATHKEEKKENMYTTGPLSLANLQASPMYNLSLQGQPIAFPTMQAGIRGLYQQTQPILAPLSISARTEPIGPSHVTNQQPQAARTNLGNNY
What is the function of this protein?
Plant specific protein that enhances G-box-binding factor (GBF) DNA binding activity.  May function as a nuclear chaperone or lever and regulate the multimeric state of GBFs.  May contribute to bZIP-mediated gene regulation.  Is able to refold denatured rhodanese in vitro (PubMed:16117846, PubMed:25387999).  Reduces DNA-binding activity of BZIP16, BZIP68 and GBF1 under non-reducing conditions through direct physical interaction.  Acts as negative co-regulator in red and blue light-mediated hypocotyl elongation.  Functions to promote hypocotyl elongation during the early stages of seedling development by regulating the repression effect by BZIP16 and the activation effect by BZIP68 and GBF1 on LHCB2. 4 expression (PubMed:25387999).  Enhances transcriptional activity of LBD18 in the EXP14 promoter.  May act as a transcriptional coactivator of LBD18 (PubMed:24484953).
What are the official names of this protein?
GBF-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the GIP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACCA_AGRRK
Sequence: MHNYLDFEKPISDLEGKIHELKKLASEDESIDTSDEVGRLEIRVRESMADIYSKLNAWQKTQVARHPQRPHFVDYAKALFTEFTPLAGDRKFSEDAAIQAGFARFRGQPVAVLGQEKGNDTKSRLKHNFGSARPEGYRKAIRILEMADRFQLPVITLVDTAGAYPGVGAEERGQAEAIARSTEMCLGLKVPIISVVIGEGGSGGAIAIAVGNRVYMLEHSIYSVISPEGAASILWRDSTRAKEAATNMKITAEDLKGLGIIDGIIPEPLGGAHRDPQTVIAAAGDVISNALGELSSRSGEQLRSDRRQKFLNMGRNL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGP1_ALLVD
Sequence: MIKSNRITACALAALFAGASFSASAWWGGPGYGNGLWDNMGDMFGDGYGDFNMSMGGGGRGYGRGYGRGNGYGYGAPYGYGAPYGYGAPYGYGAPYGYGAPYGAMPYGAMPPQMPAAPAQPQAAPSR
What is the function of this protein?
Structural protein of the sulfur globules, which are intracellular globules that serve for sulfur storage in purple sulfur bacteria.
What are the official names of this protein?
Sulfur globule protein CV1.
What is the protein family that this protein belongs to?
To C.vinosum CV2 and T.roseopersicina TR0.
Protein: SPF45_MOUSE
Sequence: MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRGGSSDDRQIADTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFSRRPDPDSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEPDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKGEAQDASKKSDSNPLTEILKCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV
What is the function of this protein?
Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step.  Involved in the regulation of alternative splicing and the utilization of cryptic splice sites (By similarity).
What are the official names of this protein?
Splicing factor 45, 45 kDa-splicing factor, RNA-binding motif protein 17.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIP80_YEAST
Sequence: MRNAGVQVDTNMQKISLQDTVLVNEMKGRVKFIGETQFAKGIWYGIELDKPLGKNDGSANGIRYFDIDLKKANSNGGYYGLFCKKDTLQFYKPDDDEHSLLNGNAAQETIKNLQVKCESLASKLNKIKIENHELKTSVEKLSTNETVLLSKISRLDKLVKELKVENGNMKTHLDNFNHLLDASDSVMAPDLDKGTLLERSHLLQGLLDQTKLSYDKAMKVQEDLLEENTQLLEENAVLSKKISDLGLQLQQTNNTIGDLALQIEAQSKSSNIVDKLTNDNILLTSNIKALNNELEELQAKEKLDENLRITYEQLEQELRLQLSNLQSALENEKEIAGTYIEENSRLKATLESIEAKTSHKFQSLELKVNTLQEELYQNKLLKKFYQIYEPFAQPHLAALSSQLQYLAEVIESENFGKLENIEIHIILKVLSSISYALHIYTIKNTPDHLETTLQCFKVNIAPISMWLSEFLQRKFSSKQETAFSICQFLEDNKFLDKDVTLILKILHPILETTVPKLLAFLRTNSNFNDNDTLCLIGSLYERSLSLIARIDKLIGKEEISKQDNRLFLYPSCDITLSSILTILFSDALFLRQDYKRISSLKKLEVFFQGIESLLENITIFPEQPSQQTSDSESQCNIKEGNFSNSLLSDRLNEENIRLKEVLVQKENMLTELETKIKIIIGRDLERKTLEENIKTLKVELNNKNEENCGKTEILNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKIYLDREKVDRVNLVSEIMELRETIRRQIKEQKRVSIDFSWLDELPAVENKQPFKEHINHSLDTLGIEMFNFVSTSRILDLKLDQPLAEDELWHERDHSYISYLKRKRKNIRLKSQNVVTYYK
What is the function of this protein?
Motor-binding component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity).  The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint.
What are the official names of this protein?
Protein NIP100, Protein NIP80.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to spindle poles throughout the cell cycle.
Protein: RNY_LACDB
Sequence: MMNNTVFPLATVAVIFLISLVVGCLIGYAIRKNVWETRAENARQSVEAILAKAKAEVEVAKAEIQAQKQAAEAVKRDAETEKKAKILEAQEEIRDYRQKVEDELNRRRDEAARKENRLQQKEDTLDHRSSLLDDREKQLTQRKAQIKQQEEKVAGLLEEAHGLVEKQNDKLLEISRLDEEEAKKIVLAQVSDHLTKEKAELIRANEEEISARADRFAHQIIVDAIQSSAADTVAETTVSVVDLPNDDMKGRIIGREGRNIRSFEAMTGVDLIIDDTPNTVTLSGFDSIRREVAKRALQKLIKDGRIHPARIEEMVDKARKEVNDDIYEAGESALMELGIHRMNPELVKILGRLKYRTSYGQNVLAHSIEVGKLAGTMAAELGLDEKLAVRAGLLHDIGKAIDHDIEGSHVEIGVELTRKYHEPDLVVNAIAAHHGDVPKLSFIADLVVAADTISSARPGARSESLENYIRRLTELEDIAGSYDGVKQAYAIQAGREVRVMVEPGKISDDEITVLAHEIRDRVEKELDYPGNIKITVIREKRAVAVAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NAS34_CAEEL
Sequence: MVSYWPVLIVLCLLPICHAKSYFADFVNGKGPFKQADALKFMDKMTILNKLQADILGIPQPDEFSALDFEDKIESKPDEIPYLFEGDMVLTDEQMDLIIKNVRDQYWARKSSTNEFLYAIRGKRSMTSFLSERWSFPVPYYIDTSSGVNTNAVLAGVAKWEQETCARFTRLNSYSSSSRQNALRFISGNGCYSNIGKVSRFPQDVSIGWGCTSLGTVCHEIGHALGFYHEQARYDRDDYVSILTQNIQDMYLSQFTKQSASSMVDYGVGYDYGSVMHYDQAAFSSTGGNTIATRDPNFQATIGQRVAPSFADVKRINFAYCNSTCSNYLDCQNGGYINPNDCNNCKCPPGFGGQLCDVAGTNSNGCGAGDITATSSIQTISASGALTCNYVIKAPVGAKVYFQMTAATFSRYSPCTTNYLEINYGRDFSRVGARFCASYPTISLSETNTLVVIYKGVNGARFSLNYRYDPVTFSTSAPTTTSTTTTTAPITVPTVSPTTTTTRQTTTTARTSTTTTTTQAPPTTTTSTSQCASWSACSAQCGGCGTQSRRCGTYVETVYCNTNPCTGGYCCRPFFYVTSFGTGYCRRPGADTPAAPQRYVEQRKG
What is the function of this protein?
Metalloprotease (By similarity).  Required for normal hatching and migration of neuroblasts.  May act by degrading eggshell proteins at hatching (PubMed:8861940).
What are the official names of this protein?
Zinc metalloproteinase nas-34, Defective hatching protein 1, Nematode astacin 34.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFA_COREF
Sequence: MTEASLNEAATAAITAFDGADNLEELAALRRDHLGDNAPIPQARRSLGTIPKDQRKDAGRFVNMALGRVEKHFAQVKAQLEEKRNREVLEQERVDVTVPTTRTQVGALHPITILNEQIADIFVGMGWEVAEGPEVEAEYFNFDALNFLPDHPARTLQDTFHIGPEGSRQVLRTHTSPVQIRSMLDREVPIYIACPGRVFRTDELDATHTPVFHQIEGLAVDKGLTMAHLRGTLDHLARELFGPETKTRMRSNYFPFTEPSAEVDVWFPNKKGGAGWIEWGGCGMVNPNVLRAVGIDPEEYSGFAFGMGIERTLQFRNGLSDMRDMVEGDVRFTLPFGIQA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_CLAM3
Sequence: MPVVLVVNSGSSSFKYQLIEMDTESVLASGLVERIGEPTGSTRHKAGGDSWERELPIADHTAGFQAMLDAFAEHGPSLEEEPPVAVGHRVVHGGDVFVEPTVVTDDVKADIDDLSALAPLHNPGALQGIAAAQTAFPDVPHVAVFDTAFHQTLPAEAYTYAIDRELAAAHRIRRYGFHGTSHKFVSEAAARLLGKPLEETRIIVLHLGNGASAAAVQGGRSIDTSMGLTPLEGLVMGTRSGDIDPAILFHLARHTDLGLDDLETLLNRRSGLLGLTGLGDMRDVQRAAADGDEAAQTALGVYRHRIRHYVGAYAAQLGGVDAVVFTAGVGENNPLVRRRSLAGLEFMGIGIDDDRNELISSEARFVSPEGSPVAVLVIPTDEELEIARQSLAATAG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_HELPJ
Sequence: MKKEVVVIGGGIVGLSCAYSMHKLGHKVCVIEKSDGTNGTSFGNAGLISAFKKAPLSCPGVVLDTLKLMLKNQAPLKFHFGLNLKLYQWILKFMTSANAKSTHRTIALFERYGWLSIDMYHQMLKDGMDFWYKEDGLLMIYTLEESFEKKLKTCDNSGAYKILNVKETKEYMPIANDNICGSVLLTENAHVDPGEVVRSLQQYLQNAGVEFLYNEEVIDFEFKNNLIEGVITHKEKIQAETIILATGANPTLIKKTKNDFLMMGAKGYSITFKMPEELKPKTSSLFADIFMAMTPRRDTVRITSKLELNTNNALIDKEQIANMKKNLAAFTQPFEMKDAIEWCGFRPLTPNDIPYLGYDKRYKNLIHATGLGWLGITFGPAIGKIIANLSQDGANEKNADIMLFSAFFRD
What is the function of this protein?
Catalyzes the oxidative deamination of D-amino acids.  Has broad substrate specificity; is mostly active on D-proline, and to a lesser extent, on several other D-amino acids such as D-alanine, D-phenylalanine and D-serine.  Mediates electron transport from D-proline to coenzyme Q1 in vitro, and is involved in the electron transport chain from D-proline to the c-type cytochrome in vivo.
What are the official names of this protein?
D-amino acid dehydrogenase, DAD.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VP1_BROAA
Sequence: IWSGIQGAF
What are the official names of this protein?
Venom peptide 1, BaP-1.
What are the subcellular locations of this protein?
Secreted.
Protein: YN8H_SCHPO
Sequence: MVREFYVTGRGRKLLPTVFRIKSFHGIVRQCVKQQRDFTSFLASSPAMGVAQGQQVKLILMLLIETWETKHQSCHSHFILLEFTHLFVRKFSQIFFEFRLFAHLLS
What are the official names of this protein?
Putative uncharacterized protein P35G2.17.
Protein: AT8B2_MOUSE
Sequence: MTVPKEIPEKWARAGAPPSWSQKKPSWGTEEERRARANDREYNEKFQYASNCIKTSKYNIVTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRHSQVLINGVLQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDVSQLARFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDSSLLEAVKMGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHELGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHPPTQELLSSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFVVTGHTVLEVREELRKARKKMVDSSHAVGNGFTYQGNLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAEATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIALTTAVCIMPVVAFRFLRLSLKPDLSDTVRYTQLVRKKQKAQHRCMRRVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFSTRSSSSWIESLRRKKSDSANSPSGGAEKPLKG
What is the function of this protein?
Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane.  May contribute to the maintenance of membrane lipid asymmetry.
What are the official names of this protein?
Phospholipid-transporting ATPase ID, ATPase class I type 8B member 2, P4-ATPase flippase complex alpha subunit ATP8B2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Efficient exit from the endoplasmic reticulum requires the presence of TMEM30A or TMEM30B.
Protein: UGPC_BORPA
Sequence: MATLSFRNVKKTYAGNVPVIHGSDMDVADGEFIVIVGPSGCGKSTLMRMVAGLETVTEGEILIDDKVVNTLEPAERDIAMVFQNYALYPHMSVFDNMAYGLKIRRLPKDEIRKRVEAAAQILELGKLLDRRPRALSGGQRQRVAMGRAIVREPKVFLFDEPLSNLDAKLRVAMRLEILKLHRRLNTTSLYVTHDQVEAMTLAHRMVVMYQGVPEQIGTPMEVFEKPASTFVAGFIGSPPMNLLEVAVGGDGIVHTSDGIALDISPLAVPQQVRGRKVVMGLRPEHMLLNAQGLAAEIEMIETLGSEQLVHGRCGKHMVVVRCSTRQFSETPARVGDTLTIGPDGRHPLHWFEADTGRRVEGL
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HBL1_MEDSA
Sequence: MGTLDTKGFTEEQEALVVKSWNAMKKNSAELGLKLFLKIFEIAPSAQKLFSFLKDSKVPLEQNTKLKPHAMSVFLMTCESAVQLRKSGKVTVRESSLKKLGANHFKYGVVDEHFEVTKFALLETIKEAVPEMWSPAMKNAWGEAYDQLVNAIKSEMKPSS
What is the function of this protein?
May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule.
What are the official names of this protein?
Non-symbiotic hemoglobin 1, MEDsa GLB1.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm. Note=But not in the nucleolus, and to a lower extent, cytoplasmic.
Protein: RM13_HUMAN
Sequence: MSSFSRAPQQWATFARIWYLLDGKMQPPGKLAAMASIRLQGLHKPVYHALSDCGDHVVIMNTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHLRDPVAIVKLAIYGMLPKNLHRRTMMERLHLFPDEYIPEDILKNLVEELPQPRKIPKRLDEYTQEEIDAFPRLWTPPEDYRL
What are the official names of this protein?
39S ribosomal protein L13, mitochondrial, L13mt, MRP-L13, Mitochondrial large ribosomal subunit protein uL13m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS12_ACAM1
Sequence: MPTIQQLIRSERYNTKKKTKSPALKSCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGTLDTAGVKDRRQGRSKYGAKRPKD
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: COX1_ORNAN
Sequence: MFINRWLFSTNHKDIGTLYLLFGAWAGMAGTALSILIRSELGQPGSLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLVSSTVEAGAGTGWTVYPPLAGNLAHAGASVDLAIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGDIKWTPPMLWALGFIFLFTVGGLTGIVLANSSLDIILHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLLSGFTLHPTWAKVHFTLMFVGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLWNALSSLGSFVSLTAVMVMIFMIWEAFASKREVLSVELTTTNIEWLHGCPPPYHTFEQPVYIKA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.