PharMolix/UniProtQA huggingface dataset:
Protein: GLPK_PSEPG
Sequence: MTDTQDKHYIIALDQGTTSSRAIIFDRDANVVGTSQREFAQHYPQAGWVEHDPMEIFATQSATMVEALAQAGISHAQVAALGITNQRETTVVWDKETGRPVYNAIVWQCRRSTEICAQLKRDGHEAYIRETTGLVTDPYFSGTKLKWILDNVEGARERAERGELLFGTIDTWLIWKFSGGKVHVTDYTNASRTLMFNIHSLQWDDKLLEILGIPRQMLPEVRPSSEVYGHTKSGIAIAGIAGDQQSALFGQMCVEPGQAKNTYGTGCFLLMNTGDQAVKSSHGLLTTIACGPRGEVAYALEGAVFNGGSTVQWLRDELKIVNDALDTEYFASKVKDSNGVYLVPAFTGLGAPYWDPYARGALFGLTRGVKVDHIIRAALESIAYQTRDVLDAMQQDCGQHLSELRVDGGAVANNFLMQFQADILGTCVERPQMRETTALGAAYLAGLACGFWSGLDELRDKAIIEREFSPQLDETQKEKLYAGWKKAVERTRDWEDHEA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: AROE_ECO45
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELTKLFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKLLQQELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MDM10_ASPCL
Sequence: MLDFMDYIQLAFAEATSWNRDNSYSSLTATAQSLLDFSTPERLRVHISSLATPHFATSYTLGTVGLIDGSVSYLYSTVPLDNTPSRSALIPLRKLARGYRQVQPPVAPVEDWGWNSLLDGLGSFQSTHAGDGNTHVSLSQKATLLHATLHLPPPTTLNALFLRRISPTMQLSLAVCSTRGPPLSKSAPQASLLGQLCHDTGKYSNEYLFSTDNSLFGWRGLWNFGPDPRHPRDPSSPPVSLLSAGAEAYYSPVSSLIGMSTGLRFSTLPAATETPSSTTTTTPISTFPYTLTLILTPLTGSLSTTYSLRASPNLAFSSRFGFNVYSWESEMVAGCELWRRRRKPQHQQDDPADHDGLEWARRKMRMHDPDYAPPTAPAPAPVAAESDEGNESVLKIRVDQSWNVRLLWEGRVKELLVSAGVGLGPSSFSPSSWSVPASGSAQAGGGGGHAKSYWHGVGVSVSYSS
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component mdm10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: Y2685_MYCTO
Sequence: MSIIAITVFVAGYALIASDRVSKTRVALTCAAIMVGAGIVGSDDVFYSHEAGIDWDVIFLLLGMMIIVSVLRHTGVFEYVAIWAVKRANAAPLRIMILLVLVTALGSALLDNVTTVLLIAPVTLLVCDRLGVNSTPFLVAEVFASNVGGAATLVGDPPNIIIASRAGLTFNDFLIHMAPAVLVVMIALIGLLPWLLGSVTAEPDRVADVLSLNEREAIHDRGLLIKCGVVLVLVFAAFIAHPVLHIQPSLVALLGAGVLVRFSGLERSDYLSSVEWDTLLFFAGLFVMVGALVKTGVVEQLARAATELTGGNELLTVGLILGISAPVSGIIDNIPYVATMTPIVTELVAAMPGHVHPDTFWWALALSADFGGNLTAVAASANVVMLGIARRSGTPISFWKFTRKGAVVTAVSLVLSAVYLWLRYFVFG
What are the official names of this protein?
Uncharacterized transporter MT2759.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MFSD6_MOUSE
Sequence: MAADDKVAILTDDEEEQKRKYVLADPFNGICREPEPPSNETPSSTETSAIPEEEIDWIEKHCVKVNNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFRKGKIVLLFSLLCWVLFNLGIGFVKPATLRCLPKIPPTAHPTNVSHPVTVLPMNSSTVAFFSTPPKLLQKRDVQLSETEPNISDIDLVSTALTLTSEPTRRPQTEAITHPVTGLILNTSTVTLPPTGNVTRETTIAVVTTTKSLPSDQVTLVYDQQEVEAIFLIILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIDVLIDGKGCKPPEYRNYQIVFIVFGVLMTMALIVATQFRFRYNHFNNSDGKGKEVEIPQVERDNSTESSEETPTAATHSQAFNFWDLIKLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQWLAVPDEEEDKTMLAERIPVPSSPVPIATIDLVQQQTEDVMPRVEARLPPKKTKHQEEQEDVNKPAWGVSSSPWVTFVYALYQVKELIQLTRESRASEIQPLQVTLCWASVASAPLLPPCSSKHMGNRKTGMLAKDISGLRSLCHSVYQVA
What is the function of this protein?
MHC class I receptor.  Binds only to H-2 class I histocompatibility antigen, K-D alpha chain (H-2K(D)).
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 6, Macrophage MHC class I receptor 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. MFSD6 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATSE_CLOD6
Sequence: MAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQDFNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKIGKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYMELKL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product.  It prefers L-threonine, L-serine and L-methionine.  It can also use O-acetyl-L-serine, L-tryptophan, L-isoleucine, L-valine, L-homoserine, 7-aminocephalosporanic acid, thiamine pyrophosphate and thiamine.
What are the official names of this protein?
Acetyltransferase CD1211, GCN5-related N-acetyltransferase, GNAT.
Protein: PFKA2_YEAST
Sequence: MTVTTPFVNGTSYCTVTAYSVQSYKAAIDFYTKFLSLENRSSPDENSTLLSNDSISLKILLRPDEKINKNVEAHLKELNSITKTQDWRSHATQSLVFNTSDILAVKDTLNAMNAPLQGYPTELFPMQLYTLDPLGNVVGVTSTKNAVSTKPTPPPAPEASAESGLSSKVHSYTDLAYRMKTTDTYPSLPKPLNRPQKAIAVMTSGGDAPGMNSNVRAIVRSAIFKGCRAFVVMEGYEGLVRGGPEYIKEFHWEDVRGWSAEGGTNIGTARCMEFKKREGRLLGAQHLIEAGVDALIVCGGDGSLTGADLFRSEWPSLIEELLKTNRISNEQYERMKHLNICGTVGSIDNDMSTTDATIGAYSALDRICKAIDYVEATANSHSRAFVVEVMGRNCGWLALLAGIATSADYIFIPEKPATSSEWQDQMCDIVSKHRSRGKRTTIVVVAEGAIAADLTPISPSDVHKVLVDRLGLDTRITTLGHVQRGGTAVAYDRILATLQGLEAVNAVLESTPDTPSPLIAVNENKIVRKPLMESVKLTKAVAEAIQAKDFKRAMSLRDTEFIEHLNNFMAINSADHNEPKLPKDKRLKIAIVNVGAPAGGINSAVYSMATYCMSQGHRPYAIYNGWSGLARHESVRSLNWKDMLGWQSRGGSEIGTNRVTPEEADLGMIAYYFQKYEFDGLIIVGGFEAFESLHQLERARESYPAFRIPMVLIPATLSNNVPGTEYSLGSDTALNALMEYCDVVKQSASSTRGRAFVVDCQGGNSGYLATYASLAVGAQVSYVPEEGISLEQLSEDIEYLAQSFEKAEGRGRFGKLILKSTNASKALSATKLAEVITAEADGRFDAKPAYPGHVQQGGLPSPIDRTRATRMAIKAVGFIKDNQAAIAEARAAEENFNADDKTISDTAAVVGVKGSHVVYNSIRQLYDYETEVSMRMPKVIHWQATRLIADHLVGRKRVD
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase subunit beta, ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase 2, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATG11_ACRCH
Sequence: MATQVLIAHTGQRLEVDTAQFSHLDDFKAWVGRNTPVAPKHFVALTPQGRTVKHASLYAEACCPSQKEIYIYDIRMSQAPSSDGSPSVVSQVPPPKRYSIPNAPNSIENVQAIASWQELYKQRRAWAVHLLEDCSAMDATARARFEEMDVMIKCVDAAVANLELSIKQIEPKYTELKKWVEPALEEHARLSTSWQQYLALARNTPVSPSMVKFMTRGQASKSNATLEDLIEPDTAKKAGTLAPTAHRRFNDKATELDRAAKKMYQTLDALIADFDKLMSRSVLGRSDESTQLLQDIEAVVKQIDSDYRTALSYSGSQKDVAQASKTASNHTERLVPNLKKRAKEMDDLLQYVTTSRNTVASDAVEFMRAITEITSLRGKLKDNIGILNQSEDDMTTFDYLRLIQQLPYMYASFLVEAIRRQEWNEKIKADSSTLANEMALFQDEEAKRRRRWQKMVGSTYGPGLDTNVIGLEVSVLGDDNSWPSVNKDELVAFLAALKDQETEEAILEDVGRLIQELNSPTKQQSKRLKAFKNGSVHEAALGRSGLMIRGDDELLRSLQDDKSKLESKLKTAESRVRRLEDLLHRQSQASRPGNLFQPQTNSIHERNDSASSVKAAPTDRQRASSEGTDTLLRRISELENELREEKQRSSRIQNDLSNRATQHDDMKNQIREVNSTKKDLLENMEALKREFVLERKSLEDEIKTLKARLEDTEDEMEHFGESREKERTSYEERAQQLEAELERIDKERRDEMLKAQGQVDFLRNENRIQREQRDTLERELQNTKDAGHATSKRLEALQEAADAHLQSLKELHSQLTGNDPVPDDGDLADVIQTKAADLLARLQNMESDTSLIRGDLDRTRDQVKELREELASTKDKLATEEAASIHVRECVSEEKAKVKALEHELAETREQLSRARARLADGETGSETLQKRVEEEEKKVASLSEELASRQSQVGSLEEELHLYKEKQEAACARASELTQRHETRDERSKELTQRLYSQNDRLCHLLERLGYAVSRKEGTMTITKVPRAERAAQNPNDSSDPGTSLRKSGMLGAKALHESADLDLLYWWNSADAATETEKYAAFMSKLGDFDADLFADTIYHRIKEVEHKARKWQKEARSYRDRAHIAQKDAHDKIAFRHFKEGDLALFLPTRNQQAGAWAAFNVGFPHYFLREQDSHRLRHREWLVARINRIQERVVDLSKSLQANDSASINDEENDNPFQLSDGLRWYLIDAQEDKPGAPATPGMGKSTVAANNVEATANIHTHMAGAKGKNRDSVHSIEGINKTLSKSLESRRSSSSSKRALPFAGAGAQALLKSNPIASETNSLRAAAPETPVATSPVQGGLLSTGEGGRPQPGAAGSSSARRPNDGPGEASGNGDAAKTAEPRRMLDRQESTGSPTKKSVVWDPLWSVDYTYESPGKK
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy (PubMed:28830792).  Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32 (By similarity).  Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation (By similarity).  Required for ATG9 anterograde transport from the mitochondria to the PAS (By similarity).  Recruits also the ATG19-prAPE1 complex to the PAS (By similarity).  Required for the Cvt vesicles completion (PubMed:28830792).  Plays a role in morphological differentiation and cephalosporin production (PubMed:28830792).
What are the official names of this protein?
Autophagy-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATG11 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole (By similarity).
Protein: Y133_MYCGA
Sequence: MPRKHLIANQINKKQQSNAKLWQKLAKEIKAAVKVGGTDPETNYRLKAAIDKALTYNLSKDSINRNIYGNSNKEDDQLIEAEYEIYGPGGLGIIVRTLSDNPNRVISSLNGYISKLKGSLAKPNSVKINFQEQGIILTDLNNYHDEALLELLIDYELIDINSDEEGYEIITVPNAYYEVKKKLEAAGFKIHHSELKLIPLLYVQLTPEQNEMFERFSASCENDDDIQWIVANNQ
What are the official names of this protein?
Probable transcriptional regulatory protein MYCGA1330.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_BRASB
Sequence: MPTINQLIANPREVQKSRKKVPALQQSPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHILRGVLDTQGVKNRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SCX10_TITOB
Sequence: MNYSTLIAVASLLTAGTESKKDGYPVEGSCAFPCGYDNAYCDKLCKERKADSGYCYWVNILCYCYGLPDNAAIKGYGRCKPGKK
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Toxin To10, T-alpha* NaTx3.9.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MES6_ARATH
Sequence: MENKNQKRFVLIHGVCHGAWTWDKVKTQLEVAGHCVTAVDLAASGINMTKVEEIQTLNDYCKPLLEFLSSLGSDDGKVIVVAHSMGGISAALAADSFACKIAAIVFLTAFMPDTINPPAYVYEKLLRSIPQEEWLDTTCVNYGKPDFPLQYTLLGPKFMAKKMYQNSPVQDLEVVKTLVRENPLVTNNLAGTRSFSEEGYGSVTRIYIVCREDLVEVEDYQRWMISNFPPKEVMEIKCADHMPMFSKPQEVCALLLEIANKYCKN
What is the function of this protein?
Putative methylesterase.
What are the official names of this protein?
Putative methylesterase 6, AtMES6, Alpha/beta fold hydrolase/esterase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
Protein: CYSZ_ECO24
Sequence: MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLIIYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSLFTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GAST_MACGI
Sequence: QLHPQDLPHLMTDLSKKKGPWQEEDAAYGWMDF
What is the function of this protein?
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes.  It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
What are the official names of this protein?
Gastrin.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YNAD_BACSU
Sequence: MHITTKRLLIREFEFKDWQAVYEYTSDSNVMKYIPEGVFTEEDAKAFVNKNKGDNAEKFPVILRDEDCLIGHIVFYKYFGEHTYEIGWVFNPNYQNKGYASEAAQAILEYGFKEMNLHRIIATCQPENIPSYRVMKKIGMRREGFFKKCIPKGNEWWDEYYYAILEEEWN
What are the official names of this protein?
Uncharacterized N-acetyltransferase YnaD.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: RIMP_SINMW
Sequence: MSDTTTAENANEPRLITETGLDRRVADIIEPVLVDLGFRLVRVRMSGQNGLTLQVMTERNDGTMTVEDCEEVSKAISPVLDVEDPIDKAYHLEVSSPGIDRPMVRRSDFIRWQGHLLKCETSVLVEGRKRFRGKIVSVDEDGFRLERDQPAYGEEAGVTIPFTALSEARLILTDELIRDALTADKKAKAARAANENFEEEDRDIE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_CROS8
Sequence: MNAEKPPVAHNVDLEEIAKFEAVASRWWDTEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILSESMAREGANVTGLDMGAEPLAVARLHALESGVELNYVQQTVEEHAAQHAGAYDVVTCMEMLEHVPDPRSVVQACAQLVKPGGHVFFSTLNRNAKSWLMAVVGAEYVLRMVPKGTHDAKKFIRPSELLGWVDETPLEERHIIGLHYNPLTNRFKLAPGVDVNYMLHTQAKKPV
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: PSBI_OEDCA
Sequence: MLTLKIFVYTVVTFFVSLFVFGFLSNDPGRNPGKRED
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TBB8_PAPHA
Sequence: MREIVLTQAGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSRLQLERIDVYYNEACGGRYVPRAVLVDLEPGTLDSVRSGPFGQIFRPDSFIFGQCGAGNNWAKGHYTEGAELMESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDARNMMAACDPRHGRYLTAAAIFRGRMPMREVDEQMFNIQNKNSSYFADWLPHNVKTAVCDIPPRGLKMSATFIGNNTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEFEEYAEEEEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.  Has a key role in meiotic spindle assembly and oocyte maturation (By similarity).
What are the official names of this protein?
Tubulin beta-8 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Protein: RLMKL_ALCBS
Sequence: MEFVATCMPGLADLLSDELGSLGISVTETGRAHVSFSGGVADALKVCLWSRLSERVLLHLATLGVTPDIAPEKLAASQDWLSLVGNNAPVHLHIEHGAEVRGDNRISAKRFIHALPEQFAISREPKGSCCIRARLDLNEAHLWLDLAGEPLHRRGYRLAGGRAPLRETLAAAILWAVGWGKEGRHSALIDPFCGSGTLVIEAALIAAGRAAGAQRQHYGFQQWRGCRRQLWLDAQKEAGESGKRPVPAVSLKGFDSEASTLQLALQNAERAGVRNAIHFERRELGALRRRDFVDNGIVVGNPPWGERLEEKPQAGWLHYALGRILSVRAPGYQALLLGADAEVMDRSGMNLEQQWRLKNGPFNNFIRLYSPRKQTPANVVKVADDSAFNVPEGAQPLLNRLRKNGKHLRRWLEREDIQCYRLYDRDLPEFNVAVDIYADQVLVQEFKAPKTIDPEKAKERRDWAVTAVRAALGVHREQVHLRTREKQKGNQQYQKLDAQGQYRVVREGQSQLLINLQDYLDTGLFLDHRPTRLRIAEEASGKRFLNLFAYTGSATVHAAVGGAKRTVTVDSSKRYLDWAACNLAANGFSTDQHELARADTMRWLDECKEQFDLVFCDPPTFSNNKSRSDFVVEEHHGDLIRKIMRCLEPGGVLYFSCNYRRFQMDESISKWYAVEDISRWSIPEDFRRNEKIHYCYAIRHVEDA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_CHLAA
Sequence: MSKIDSIIEMIEGLNVLELVELKKKMEEKWGVTAAAPVMAMGAAMPVAAAGDGAAAAAPVEEKTEFDVILKEAGPNKIQVIKVVRELTSLGLKEAKDLVEGAPKPVREGVSKEEAEAAKAKLTEAGAVVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RNJ1_STAAC
Sequence: MKQLHPNEVGVYALGGLGEIGKNTYAVEYKDEIVIIDAGIKFPDDNLLGIDYVIPDYTYLVQNQDKIVGLFITHGHEDHIGGVPFLLKQLNIPIYGGPLALGLIRNKLEEHHLLRTAKLNEINEDSVIKSKHFTISFYLTTHSIPETYGVIVDTPEGKVVHTGDFKFDFTPVGKPANIAKMAQLGEEGVLCLLSDSTNSLVPDFTLSEREVGQNVDKIFRNCKGRIIFATFASNIYRVQQAVEAAIKNNRKIVTFGRSMENNIKIGMELGYIKAPPETFIEPNKINTVPKHELLILCTGSQGEPMAALSRIANGTHKQIKIIPEDTVVFSSSPIPGNTKSINRTINSLYKAGADVIHSKISNIHTSGHGSQGDQQLMLRLIKPKYFLPIHGEYRMLKAHGETGVECGVEEDNVFIFDIGDVLALTHDSARKAGRIPSGNVLVDGSGIGDIGNVVIRDRKLLSEEGLVIVVVSIDFNTNKLLSGPDIISRGFVYMRESGQLIYDAQRKIKTDVISKLNQNKDIQWHQIKSSIIETLQPYLFEKTARKPMILPVIMKVNEQKESNNK
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J 1, RNase J1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_XANOM
Sequence: MRLVLLGPPGSGKGTQATRLKDTFEIPHISTGDLLRAEVAAGSPLGLKAKEVMARGDLVSDDILLGMLEARLGQADVAKGFILDGYPRNVAQANALCALLSKIGQPLDAVVQLDVASELLVERIAGRAKAEGREDDNPESVRKRLQVYTDSTAPVIGFYEQRGKLTRVDGVGSLDEVLERIRKALGR
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RELE1_METJA
Sequence: MKFNVEIHKRVLKDLKDLPPSNLKKFKELIETLKTNPIPKEKFDIKRLKGSDEVYRVRIGKFRVQYVVLWDDRIIIIRKISRREGAYKNP
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its cognate antitoxin is RelB1 (Potential).
What are the official names of this protein?
Putative toxin RelE1.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family.
Protein: EFTS_MYCS5
Sequence: MSQNKLELIKELRQRTNSALGDVKKALEATDYNIEAAIKWLKENGIVKAAKKSGRLASEGVVSAHGTPTQSLLLEVNSETDFVAQNEKFMTLVKNVTESVFKAGASTLEEALQVKVSDSETVEQALTDATAVIGEKITLRRVLASKAKEGHVLGTYLHANNRVAAVVEVTGSNSEVAKNVAMHLAAMNPEFVLVSDIPEDRMQEIKKAFEAPKDFDKKPAQIQERILSGWLDKQLGEVVLEKQPFVMEDSLTVAKYLANANAKLVSAHRYEVGEGLEKVQSNFAEEVASMTK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB5C_PONAB
Sequence: MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNRGVDLQENNPASRSQCCSN
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic.
What are the official names of this protein?
Ras-related protein Rab-5C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome.