PharMolix/UniProtQA huggingface dataset:
Protein: GLRX4_YEAST
Sequence: MTVVEIKSQDQFTQLTTTNAANKLIVLYFKAQWADPCKTMSQVLEAVSEKVRQEDVRFLSIDADEHPEISDLFEIAAVPYFVFIQNGTIVKEISAADPKEFVKSLEILSNASASLANNAKGPKSTSDEESSGSSDDEEDETEEEINARLVKLVQAAPVMLFMKGSPSEPKCGFSRQLVGILREHQIRFGFFDILRDENVRQSLKKFSDWPTFPQLYINGEFQGGLDIIKESIEEDPEYFQHALQ
What is the function of this protein?
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (By similarity).  Binds one iron-sulfur cluster per dimer.  The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit (Probable).
What are the official names of this protein?
Monothiol glutaredoxin-4.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. Monothiol subfamily.
Protein: MSBP2_ORYSJ
Sequence: MATCSAACARPAVVVFASPAAARRRAASSVYLPGRPLRGGGVVRCSAGPVSGGMISKKVAELWAAARSASPVAVIAAVAGAAVVYKVGSSLLAPPPPPARPREEPSEEAPPPPEPVQVGEITAEELLQYDGSDPEKPLLMAIKGQIYDVSQSRLFYGPGGPYALFAGKDASRALAKMSFEPQDLTDDISGLSLLELSALQDWEYKFSSKYVKVGTIKKVLVEQGGDSTADAIEEAAVDGEDSILTAKMSNQLLYEEEMEVGSDDP
What is the function of this protein?
Binds multiple steroid compounds.
What are the official names of this protein?
Membrane steroid-binding protein 2, OsMSBP2, OsMSBP1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: C71Z6_MAIZE
Sequence: MEDKVLLAVAMVALIAVLSKLKSLLETKPKLNLPPGPWTLPLIGSIHHLVSSPLPYRAMRELAHKHGPLMMLWLGEVPTLVVSSPEAAQAITKTHDVTFADRHMNSTVDILTFNGNDIVFGTYGEQWRQLRKLSVLELLSVARVQSFQRIREEEVARFMRNLAASAGAGATVDLSKMISSFINDTFVRESIGSRCKHQDEYLDALHTGIRVAAELSVANLFPSSRLLQSLSTARRKAVAARDEMARILGQIIRETKEAMDWGDKASNESMISVLLRLQKEAGLPIELTDDIVMALMFDLFGAGSDTSSTTLTWCMTEMIRYPATMAKAQAEVREAFKGKTTITEDDLSRANLSYLKLVVKEALRLHCPVPLLIPRKCRETCQIMGYDIPKDTCVLVNVWAICRDSRYWEDADEFKPERFENSSLDYKGTSHEYLPFGSGRRMCPGGNLGVANMELALASLLYHFDWKLPSGQEPKDVDVWEAAGLVGRKNAGLVLHPVSRFAPVNA
What is the function of this protein?
Involved in the production of antifungal dolabralexin phytoalexins in response to biotic and abiotic stresses (PubMed:29475898).  Catalyzes the epoxidation of dolabradiene at C-16, followed by hydroxylation at C-3, to yield the epoxides 15,16-epoxydolabrene (epoxydolabrene) and 3b-hydroxy-15,16-epoxydolabrene (epoxydolabranol) (PubMed:29475898).
What are the official names of this protein?
Dolabradiene monooxygenase, Cytochrome P450 71Z16, ZmCYP71Z16.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GDL60_ARATH
Sequence: MDYTVSSLQCFFLVLCLSLLVCSNSETSYKSNKKPILINFGDSNSDTGGVLAGVGLPIGLPHGITFFHRGTGRLGDGRLIVDFYCEHLKMTYLSPYLDSLSPNFKRGVNFAVSGATALPIFSFPLAIQIRQFVHFKNRSQELISSGRRDLIDDNGFRNALYMIDIGQNDLLLALYDSNLTYAPVVEKIPSMLLEIKKAIQTVYLYGGRKFWVHNTGPLGCAPKELAIHLHNDSDLDPIGCFRVHNEVAKAFNKGLLSLCNELRSQFKDATLVYVDIYSIKYKLSADFKLYGFVDPLMACCGYGGRPNNYDRKATCGQPGSTICRDVTKAIVWDGVHYTEAANRFVVDAVLTNRYSYPKNSLDRFW
What are the official names of this protein?
GDSL esterase/lipase At3g62280, Extracellular lipase At3g62280.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: INT6L_MOUSE
Sequence: MPILLFLIDTSASMNQRTDLGTSYLDIAKGAVELFLKLRARDPASRGDRYMLVTYDEPPYCIKAGWKENHATFMNELKNLQASGLTTLGQALRSSFDLLNLNRLISGIDNYGQGRNPFFLEPSILITITDGNKLTSTASVQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVASTEPEQLGSVPSDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVQSGVVINFEKTGPDPLPVGEDTLMELCRPSNLFAAQPWHSCHKLIYVRPNSKTGVPVGHWPIPESFWPEQNLPSLPPRTSHPVVRFSCVDCEPMVIDKLPFDKYELEPSPLTQYILERKSPHTCWQVFVTSSSKYNELGYPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQAFDSYLKTLPPYYLITKLESDQILASVGKKPPQEIGIKVKNHSACGLPLAHNKSFRKLLKEIIGESAPRLTELNPKEFAGFQVGLLNKDLKPQTYRNAYDIPRRGLLDQLTRMRSNLLQTRKFIVGQDEDSLHSVPVAQMGNYQEYLKMLASPLRELDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVVGPQNKVKRPGEPNSPMSSKRRRSMSLLLRRAQTAPTVTNHVGGKGPLSASWFPSCPSLVKHTFGHPDTTVIHDTHEEKMENGQSPPDGFLLKSAPAEFMNVSGESFISSQLDSLSDDFTGLRKDGFIHKPGNNILLGGAKTCSLSVADQKITMASALETVPNSMQITPAMAQGINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLETKKQFVEFTIKEAARFKRRVLIQYLEKVLEKIDSHHLLNNVNHINSRSSC
What are the official names of this protein?
Integrator complex subunit 6-like, Protein DDX26B.
Protein: RUVA_GEODF
Sequence: MIALLTGKLAHKSPDFIILDVNGVGYRVQIPFSTYYALPEGGSSVSLNIFTHVKEDAINLYGFRTMEEKEMFQLLISVSGIGPKLGNGILSNIEAQNLSDALIRGDLARLATIPGIGKKTAERLVLELREKVKKLGHGPLQQDVAPADAHNDMRDDVVSALVNLGYKEAVVQKTVDEIGVAADATVESLLKQALKKLMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: GATB_PHYPA
Sequence: MASWRCLELARGVGTSILFREAAALGSLKWKRTATAAGASQITNCLHSVASNSKREPRPVKTRVMTQERGSGETQTTADKYEAVIGIETHVQLGTSTKAFCSCPSEYGSEPNANVCPVCMGLPGALPVLNAAVVESGVKLGLALQANIALKSKFDRKQYFYPDLPKGYQISQFDIPIAEKGYIDVDLPVEFGGGHRRFGVTRVHMEEDAGKLIHAGNDRLSGSSSSQVDLNRAGVPLLEVVSEPEMRTGLEAAEYAAELQRMVRYLGISNGNMQEGSMRCDVNISIRPKGREQFGTKVEIKNMNSFSAMQKAIEFEMDRQIALLEEGERIKQETRLWEEGSQQTISMRSKEGLADYRYFPEPDLPEVVLSQEYIDTTRANLPELPDAKRRRYESLGLSMQDTLVLANDSDVAAFFDEVLEKGTEVKQAANWIMGDVAAHLKSIKLTITEAKLTPASLAELIGLIKDGTISGKIAKEILPELIEKGGSAKGAVESKGLSQISDPAVIESMVDKILADNVKQVEAYRGGKTKLQGFFVGQAMKASGGRVNPGLLNKILMAKLNG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Plastid, chloroplast.
Protein: RL35_PROM3
Sequence: MPKLKTRKAAAKRFKATVTGKFMRRRAFRNHLLDHKSPKLKRHLATKAVVDERDAENVRLMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PARC_SHIFL
Sequence: MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FT105_SCHPO
Sequence: MGGQESKLAFQRGIARLASQPDIPLDDEVWVSLWSVPESCPEVYDFFPPGLIREMRDHAFVNLEKLLLVLTSRLFALKNDKKFPNPETAPASEALNCIRLLTRIIPFLNEKLDLEEWHQKFWWSLRKKRNLPKENSELDLSNFQDDLDFENSISQKNEFSQKSPSVPLSPVSTFPASSISLDASSDVSAADVSVGGSSTIKEIGSIEETFTHEKTLMEELLDTVFRLLFCRGFTLPLSSPEQYAYIIWENGIGTTETQEKTTKELAFNRIEVLRLLLVLISKRLYRSSEVASHTLTYLTCVANKQLILVFLYSLINTTLRLRPDSWKASYSTLVPYNDSSIALSKLTSQILLLFLDHTPHETTVEYFRQRLNLSPGAAIENQYRLYFSRLQLQADYEFLVNELYRLLNAPVSAISAYISIVQKPNIAFPEIILFLWQAILYNKRFRAFLITSPYATEFLTSIQFYALRYREDNEHSGLVRICLFIVHYLSCEKVLCEKLNRNCMNAQSLMSSLGFSVPPMSYAEFLIISSFHISAVKRSPFSSLSPVILLTICNIAPFVENLSFVTCAKLMQLCSSLSSPRFLFRNPRNHLLLEYLLQAISSIVENKFSQNPNLSYSIIRLQQVFLNLNSMKLPAVAQTKSQPLVALNSEGSSDFESKSSDNTSLDGTPLQNTDFKKVATVEDDSPFDELDKFSSPFSSSSSRGGLSHISSRNVSISVPTVLQDVFSDSPLVLSRKLRGKIPENVSSSELIKKCASNPFGKDLEIDSNLFAPSNSWFNSWHSRLELDSILAIISQFSLPVYKKMNEELSTTDEAVKLLANSVLNDVHPRVPNFRYFIWSVPMNNWFQSLVWLYTLSFDEKGLMATPSLFTTSKVYKQHGNIMKVASPENSSNSMENATKSILDKLDLLYLQLPSSVNHDSSLRNK
What is the function of this protein?
Required for the localization of ubp5 to the Golgi apparatus.  Involved in detoxification of cadmium ion.
What are the official names of this protein?
Ubp5-interacting protein ftp105, Down-regulated in multiple cancers 1 homolog 3, Hid-1 family protein ftp105.
What is the protein family that this protein belongs to?
Belongs to the hid-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: CND1_XENLA
Sequence: MTFHFHIPLAFRDLLKSGGIGQYVVQEVLPVRHVDAQFAAFQTSFRTEAPLCILQHFDTLYSILHHFRSLDIAIKEDVLEVMVKVASRHANELPAILEDLNLSVPQRAAHLNALKMNCFILTQLIEAFEAETYKASLGSVEPSGKGKKAKSKPEGFSWESERESILQALTHLLQLDIRRLWSMSVVEEEFVSMMTSCCYKMMENPNIVMAKNKSTREALGHLLGVTVKRYNHMLSASVKVIQLLQHFEHLASVLVHTVSLWATEYGMKPVIGEIMREIGQKCSQDLSRESSGFKAFATFLTELAERIPAIMMPSISVLLDYLDGENYMMRNSVLTVMGEMVVRVLSGDQLEEAEKSSRDQFLDTLQEHLHDVNTYVRSCVIQIYNRIVQEKALPLSRFQSVVTLVVGRLFDKSVNVCKNAIQLLASFLANNPFTCKLSSVDLKVPLEKETKKLKEMREKYQGPKPVVVISPEEEWEAMLPEVLEAFKILQQESKEEEDIETEEIESSQHLREQILILLRKTSYKNSIRLTQKGIERFQEDPLFSEGDSEAKSELGILEKIFTEKKADLEQPTTKDQDDAQVNPTSEELPSQEVQNSDMDKQEMLVQYLSDAHHFALKIEEAIDVISKMMYETAVSVVQEVIEFFVTVSQFGVSQALLGVRRMLPLVWSKEPGVREAVLSAYRRLYLSSNGESERVKAQALVRSLSLLMVDSSAGILQCLEEIVSEFVQKGDIHPSVIQLLWEKFTQKSPCSEFERRAAVMLLGMMTRGQPEIVMSNLDTLVSVGLGEQVQKDYQLAREVCNCILKITDSQKQTLGKSTEPFRLPKDHSLFVCLTEAVAGGIGLSGLHWLPFKETAVRLVYELGEEPEEICSEILLRCSQNVLDGHQTQDEVPNVPAFLLTHLLSLAGDVALQQVVHLERAVSAELRRRRVLKEEQEAEKVGKQRKSKANESTMEEELGLVGASADDIEAELIRKICDTELLGGQQYLSAFLPLILRICNNPGRYSDPDLCTVATLALAKYMMISSDFCDTHLRLLFTLLEKSPLPSVRSNIMIALGDLSIRFPNLIEPWTPNLYARLRDPSREVRKTAGMVMTHLILKDMVKVKGQVSEMAVLLIESDQEISALARNFFNELSNKGNAVYNLLPDIISRLSDPDCGVEEEAFRTIMKQLLSYITKDKQTESLVEKMCHRFRTARTERQWRDLAHCLSLLPFSEKGLRKMQDCFDCYGDKLSDEAVYNSFLTTVAKMRRGAKPELKALIDEFEQKLSRCHNKGLENMDVPEEPSAESDAQPPKAKRPPLASVNVKKGKSEDDFQTPKPPASRKSRRKVAVNFSSDEESDLEAELSEAETPKNPTPIRRTARSRAK
What is the function of this protein?
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.  May target the condensin complex to DNA via its C-terminal domain.
What are the official names of this protein?
Condensin complex subunit 1, Chromosome assembly protein XCAP-D2, Chromosome condensation-related SMC-associated protein 1, Chromosome-associated protein D2, Eg7, Non-SMC condensin I complex subunit D2.
What is the protein family that this protein belongs to?
Belongs to the CND1 (condensin subunit 1) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Protein: LDH1_LACLC
Sequence: MADKQRKKVILVGDGAVGSSYAFALVNQGIAQELGIVDLFKEKTQGDAEDLSHALAFTSPKKIYSADYSDASDADLVVLTSGAPQKPGETRLDLVEKNLRITKDVVTKIVASGFKGIFLVAANPVDILTYATWKFSGFPKNRVVGSGTSLDTARFRQALAEKVDVDARSIHAYIMGEHGDSEFAVWSHANVAGVKLEQWFQENDYLNEAEIVKLFESVRDAAYSIIAKKGATFYGVAVALARITKAILDDEHAVLPVSVFQDGQYGVSDCYLGQPAVVGAEGVVNPIHIPLNDAEMQKMEASGAQLKAIIDEAFAKEEFASAVKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_AGRFC
Sequence: MNGKKLPDGGILFDETDDEDDDANLAATDTAEASRSVAGMDWNAGWKNESGLKGMDLIGEFVKHLPNSPGVYRMFNEAGDVLYVGKARSLKKRVGNYAQGRVHSNRIAQMVRFTTHMEFVTTRTETEALLLEANLIKRLRPRFNVLLRDDKSFPYILITADNRAPAIFKHRGARARKGDYFGPFASAGAVGRTINSLQRAFLIRTCTDSVFETRTRPCLLYQIKRCSGPCTHEVSDEGYAELVKEAKDFLSGKSQAVKTAIARQMNEASEDLDFERAAIYRDRLAALSHVQSHQGINPAGIEEADVFAIHHEGGISCIQVFFFRTGQNWGNRAYFPKADPSLPGSEILNAFLAQFYDDKPVPKQILLSETVEEQELLAAALGEKAGHKVTISVPQRGEKKDITDHVLANAREAHGRKLAETSSQARLLKGFAETFNLPYVPRRIEIYDNSHIMGTNAVGGMVVAGPEGFVKNQYRKFNIKSTDITPGDDFGMMREVMTRRFSRLLKEEGKPDRAQTPTPEEAADLPFPAWPDVILIDGGQGQMTAVRAILDELGIRDCVTAIGVAKGVDREAGRERFFADGRSDFSLPPRDPVLYFIQRMRDEAHRFAIGSHRARRKKEMVRNPLDEISGIGPGRKRSLLQHFGTAKAVSRAGLNDLMTVTGISETVARQIYNHFHESGSD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK1_HOPMA
Sequence: QGLIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPB_ECO45
Sequence: MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CTEME
Sequence: MTNTRKSHPLIKIVNHSFIDLPAPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFTILILMPSTALMENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RDRP_TBRFV
Sequence: MAYTQTATTSALLDTVRGNNTLVNDLAKRRLYDTAVDEFNARDRRPKVNFSKVISEEQTLIATRAYPEFQITFYNTQNAVHSLAGGLRSLELEYLMMQIPYGSLTYDIGGNFASHLFKGRAYVHCCMPNLDVRDIMRHEGQKDSIELYLSRLERGNKVVPNFQKEAFDRYAETPDEVVCHSTFQTCTHQQVENTGRVYAIALHSIYDIPADEFGAALLRKNVHVCYAAFHFSENLLLEDSHVNLDEINACFSRDGDKLTFSFASESTLNYCHSYSNILKYVCKTYFPASNREVYMKEFLVTRVNTWFCKFSRIDTFLLYKGVAHKGVNSEQFYSAMEDAWHYKKTLAMCNSERILLEDSSSVNYWFPKMRDMVIVPLFDISLDTSKRTRKEVLVSKDFVFTVLNHIRTYQAKALTYSNVLSFVESIRSRVIINGVTARSEWDVDKSLLQSLSMTFFLHTKLAVLKDELLISKFSLGPKSVSQHVWDEISLAFGNAFPSIKERLLNRKLIKVSGDALEIRVPDLYVTFHDRLVTEYKTSVDMPVLDIRKRMEETEVMYNALSELSVLKESDKFDVDVFSRMCQTLEVDPMTAAKVIVAVMSNESGLTLTFEQPTEANVALALKDSEKASEGALVVTSRDVEEPSMKGSMARGELQLAGLSGDQPESSYTRNEEIESLEQFHMATASSLIRKQMSSIVYTGPIKVQQMKNFIDSLVASLSAAVSNLVKILKDTAAIDLETRQKFGVLDVATKRWLIKPLAKNHAWGVIETHARKYHVALLEYDEHGVVTCDSWRRVAVSSESMVYSDMAKLRTLRRLLRDGEPHVSSAKVVLVDGVPGCGKTKEILSKVNFEEDLILVPGKQAAEMIKRRANASGIIQATRDNVRTVDSFIMNYGKGTRCQFKRLFIDEGLMLHTGCVNFLVSMSLCEIAYVYGDTQQIPYINRVSGFPYPAHFAKIEVDEVETRRTTLRCPADITHYLNRRYEGYVMCTSSVKKSVSQEMVSGAAMINPVSKPLNGKVLTFTQSDKEALLSRGYTDVHTVHEVQGETYADVSLVRLTPTPVSIIAGDSPHVLVALSRHTQTLKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAGTQXQLQVDSVFKGSNLFVAAPKTGDISDMQFYYDKCLPGNSTMLNNYDAVTMRLTDISLNVKDCILDFSKSVAAPKDPIKPLIPMVRTAAEMPRQTGLLENLVAMIKRNFNSPELSGIIDIENTASLVVDKFFDSYLLKEKRKPNKNVSLFCRESLNRWLEKQEQVTIGQLADFDFVDLPAVDQYRHMIKAQPKQKLDTSIQSEYPALQTIVYHSKKINAIFGPLFSELTRQMLESIDSSKFLFFTRKTPAQIEDFFGDLDSHVPMDILELDISKYDKSQNEFHCAVEYEIWRRLGLEDFLGEVWKQGHRKTTLKDYTAGIKTCLWYQRKSGDVTTFIGNTVIIAACLASMLPMEKIIKGAFCGDDSLLYFPKGCEFPDIQHTANLMWNFEAKLFRKQYGYFCGRYVIHHDRGCIVYYDPLKLISKLGAKHIKDWDHLEEFRRSLCDVANSLNNCAYYTQLDDAVSEVHKTAPPGSFVYKSLVKYLSDKVLFRSLFIDGSC
What is the function of this protein?
Is a methyltransferase active in RNA capping and an RNA helicase.  Methyltransferase displays a cytoplasmic capping enzyme activity.  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus.  Helicase region probably exhibits NTPase and RNA unwinding activities.  It also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  May mediate silencing suppression through either inhibition of HEN1-mediated siRNA or siRNA demethylation.
What are the official names of this protein?
Replicase large subunit, 183 kDa protein, RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: RNY_STRSV
Sequence: MDLFPIIMSVFAAIIGLVIGYVSVSAKMKSSKEAAELTLLNAEQEATNLRGQAEREADLIVKEAKRETSSLKKEALLEAKEEARKYREQVDAEFKSERQELKQIESRLTERASTLDRKDDNLSNKEKALEQKEQSLSDKSKHIDAREEQVAELEKQKAAELERVASLSQTEARDIILTQTEDKLSKEIATRIRDAEQDIKERSDKVAKNILVQAMQRIAGDYVAEQTNSTVHLPDDSMKGRIIGREGRNIRTFESLTGIDVIIDDTPEVVTLSGFDPIRREIARMTMEALLKDGRIHPARIEELVEKNRLEIDNRIREYGEAAAYEIGAPNLHPDLMKIMGRLQFRTSYGQNVLRHSIEVAKLSGIIAAELGENANLARRAGFLHDIGKSIDREVEGSHVEIGTELARKYKEHPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGARSESLESYIKRLQDLEEIANSFKGVKNSFALQAGREIRIMVQPDKIKDDKITILAHDVREKIENNLEYPGNIKVTVIREMRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MD342_PENRW
Sequence: MAFNFNWSPLMADASFYTRAQDLLTAALNKSPKPPIIVDDIHVTELNLGSIPPELEILEIGDLAEDRFRGIFKMSYTGDAFLTLKTRVQANPLNTFLLTRPTFGSPVPLAAATPLTIPLQITLSDFKLSGFVILVFSKQKGITVVFRNDPLESLKVSSTFDSIPFVRDFLQKEIEAQLRILFMDELPAIIHRLSLRLWVPEYRTGEEMNDETDNTAKSSEGPGQDPLASPPQDPVDSLGNALNESEIASLSLDSSVETHSLFSQKNLLRLAALTDSQRTLSLFTPSIQEVVYRAWTSPTDTSEFPSSVISPLSPTLSREQSQMGSMSSLHETASNASMQSRPSMSSHSFSTSTYGLSLGAGRHSKAHARKRKKRVVDLRRPKTTDDAMSVSDESVMTESSRPPSIASAPLPIVNEPSDDPVTPPLSPEVDCHLPIIPERHLPSFSRPTRRDADLSYSHETIRGPKAEDVDATPRATMRGYPQERAEAGPSSNQRTPLPAAVLPFSKDENANVDPVLVDRLAGEIARRMREDKLMTNACSGFWSRQHEDSPPPAYGH
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34-2.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: H2A2A_RAT
Sequence: MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Histone H2A type 2-A, H2A-clustered histone 18, Histone H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MAZF4_MYCTU
Sequence: MNAPLRGQVYRCDLGYGAKPWLIVSNNARNRHTADVVAVRLTTTRRTIPTWVAMGPSDPLTGYVNADNIETLGKDELGDYLGEVTPATMNKINTALATALGLPWP
What is the function of this protein?
Residues 29-56 inhibit ssDNA cleavage by DNA topoisomerase.  This fragment does not have mRNA cleavage activity but it inhibits growth upon overexpression in M. smegmatis.
What are the official names of this protein?
Endoribonuclease MazF4, Toxin MazF4, mRNA interferase MazF-mt7.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: CLPS_BRUSI
Sequence: MRRINTIMQGKTNGGNGPESGTVVVTRTQPKTRKPSLYRVLLLNDDYTPMEFVVHVLQRFFQKNLDDATRIMLHVHNHGVGECGVFTYEVAETKVSQVMDFARQNQHPLQCVMEKK
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.