PharMolix/UniProtQA huggingface dataset:
Protein: COXX2_RHILO
Sequence: MALVDETSIDEAGFRMSEATAGDFFALLKPRVMSLVVFTAFVGLVAAPVTINPLLAVIAILSIAIGAGASGALNMWYDADIDAVMTRTASRPVPSGRIQPHEALSFGLVLSVLSVMTLGVLVNWLSATLLAFTIFFYAVVYTMWLKRWTPQNIVIGGAAGAIPPVIGWAAVTGSVSLESIVLFLIIFLWTPPHFWALALFKSGDYERAGIPMMPNVAGHASTRRQIFAYALVLAPVGVAPWLLGYTTPFYGVAAMLLGLGFVWYAWKVLGMADDDRAMKPAKALFAYSLLYLFAIFAAYLADSVVERALAMGGA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OPLA_DICDI
Sequence: MTIDKLKKSIKFNIDRGGTFTDIYAEFPYEPYYIVEKLLSVDPENYSDAPREGIRRILERIQGKSISKENVDTYAIKSIRMGTTVGTNALLERKGEKVLLVTSKGFRDLLQIGNQSRPKIFELNITKPELIYNSVVELDERVQIVTNDQVLNDIKLESPNSLKKGTTGDYIKVLEIPNRDKIKSELLKYFVKGIKSIAVVFIHSYTFHDHELLVGEIAKEIGFEHISLSHQLMPMIKAVPRGLTSCVDAYLTPLIELYIKNFTKGFDSNIGDVDISFMMSDGGLCPVDSFRGFRSILSGPAGGVVGYSKTTSTVIESHKNNNGNNEIKQQPIIGFDMGGTSTDVSRYNGTLDHVFETEISGLTIQAPQLDIHTVAAGGGSRLFFKSGLFLVGPESVGAHPGPVCYKKNGQLAITDANLLLGRLLPEYFPPIFGPNQNEPLDLEATKKAFKELTDEINQFQQNNNLPLMTEDQVAFGFIRVANEAMCRPIRNITEAKGFDCSQHVLACFGGAGGQHSCSIAQNLGMPKVFIHRFSGILSAYGLGLADLVIDTQEPCSLIYNKENKSTFEKQLNQLKENAKQQLLNKGFPEEEIFCEGFLNLRFSGTDTAMMIKTPDNHDYEAEFKSNYKREFGFLILGRDLLIDDIRVRVHARGSDLNSLRINDSTGEPLKPETIQKCYFESVGRIDTPIYLLKSLCGGDSIDGPAIIIDNTTTIVVEPNCKANILKPSGNIEILIGGGKSKTVTTELDPIMLSVFSHRFMSIAEQMGKIIIRTSISTNIKERLDFSCALFSPDGGLVANAPAIPIHVGSMQNAVKYQVETLGSNWKEGEVVLSNHPQAGGSHLPDLTVMTPVYHKGEIVFFVASRGHHADIGGITPGSMPPFSKSISEEGAAIMSLKIVKDGHFQEEAVRKTFEKSRNLSDNISDLKAQIAANHKGIQLMQELINHYGLDVVHAYMYHIQKNAELAVRDMLYDISISNNLKPLDTLISTDYMDDGSKIELKLTIDREKKSAIFDWSGSGVEVYGNTNAPTSITLSATIYSLRAMVKSEIPLNQGCLAPILTVIPPGSILNPSFDSAVVGGNVLTSQRLTDVILSAFGACANSQGCMNNLTFGDETLGYYETIAGGTGAGPNFNGFTAVQSHMTNTRITDVEIMEKRYPVIVKEFSVRYGSGGDGKFKGGDGVVREIQFLKNFTVSILSERRSLQPRGLMGGENAERGLNLVLKNNGKYINIGSKNSINIERNESIIIFTPGGGGFGQKDSMITDN
What is the function of this protein?
Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase, 5-oxo-L-prolinase, 5-OPase, Pyroglutamase.
What is the protein family that this protein belongs to?
Belongs to the oxoprolinase family.
Protein: Y2157_YERPN
Sequence: MTIKPSDSVSWFQVLQRGQHYMKTWPADKRLAPVFPENRVTVVTRFGIRFMPPLAIFTLTWQIALGGQLGPAIATALFACGLPLQGLWWLGKRAITPLPPTLLQWFHEVRHKLFEAGQAVAPIEPIPTYQSLADLLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YPN_2157.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TUSA_PSEA8
Sequence: MTHSVDAILDATGLNCPEPVMMLHNKVRDLAPGGLLKVIATDPSTRRDIPKFCVFLGHELVEQQEEAGTYLYWIRKKAD
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_MYCPA
Sequence: MTTILAIETSCDETGVGIARLDADGAVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPTMRRALSAAGVTKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYQHGPLPECVALLVSGGHTHLLQVRSLGDPIVELGSTVDDAAGEAYDKVARLLGLGYPGGRVLDELARTGDREAIVFPRGMTGPRDAPYAFSFSGLKTAVARYLESHPDAVNADVAAGFQEAVADVLTRKAVRAATDLGVTTLLIAGGVAANSRLRELAEQRCAAAGLTLRIPRPGLCTDNGAMIASFAAHLVAAGAPPSPLDVPTDPGLPVVKAQVS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZC21B_MOUSE
Sequence: MGEAQLLVEDGNQKLFPCEVCGRCFATDVLERHGPICKKVFNKKRKPFNSLKQRLQGTDIPTVGKSPQPKVQPVRKSNWRQQHEDFINTIRSAKQFTLAIKEGRPLPPPPRPTSNPDYIQCPYCMRRFNETAAQRHINFCKNQTSRPVFDPIQMAARLVSRAQCKAQASLKK
What are the official names of this protein?
Zinc finger C2HC domain-containing protein 1B.
What is the protein family that this protein belongs to?
Belongs to the ZC2HC1 family.
Protein: VATB_CLOB1
Sequence: MLKEYRTVKEVVGPLMLVDQVDGVSFDELVEIELHNGEKRRGKVLEINKDKAMVQLFEGSAGINLKGAKVKFLGKPLELGVSEDMLGRVFDGLGNPKDGGPKIIPDKKLDINGIPINPVARNYPDEFIQTGVSAIDGLNTLVRGQKLPVFSGSGLPHAELAAQIARQAKVLNSDSKFAVVFAAIGTTFEEAQYFIDDFTKTGAIDRAVLFINLANDPAIERIATPRMALTAAEYLAFEKGMHVLVIMTDITNYCEALREVSAARKEVPGRRGYPGYLYTDLSTLYERAGRILGKEGSITQIPILTMPEDDKTHPIPDLTGYITEGQIILSRELYKKGIMPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFSAYAQGKQAKELSVILGESALSDTDKLYAKFADAFEEEYVSQGFTTNRTIEETLNLGWKLLTILPKSELKRIRDEYLEKYLNKAEESK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: NDK_SULIM
Sequence: MVMQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDIAEKLYDEHKGKSFFEELVNYVTSGPVVCMVIEGDDVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASDSIEKAQREMSLFFDKSDL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GT14C_ARATH
Sequence: MKRSHISSPRSYSRPAISIFGVFLLFLLVLTLSSRKPSDSSSGLAPNRNLATKSTIPRFAYLVTGTKGDGKRVKRLLKAIHHPRNYYLLHLDLEASDEERMELAKYVRSEKKKFENVMVMGLADLVTEKGPTMLASTLHGVAILLKKAKDWDWFINLSASDYPLMPQDDILHIFSYLPRYLNFIEHTSNIGWKENQRARPIIIDPGFYHLKKSGVFWAKERRSLPASFKLFMGSTSVALTRPFLEFCIWGWDNLPRTLLMYYTNFLLSSEGYFQTVVCNNKDYQNTTVNHDLHYTKWDPLQQRTLNVTVENFRDMVQSGAPFAREFREDDLVLDKIDIELLGQTDTGLELKTPDVVKPTVSWKRLEKLMVRLLDHENFRAKQCK
What is the function of this protein?
Beta-glucuronosyltransferase involved in the biosynthesis of type II arabinogalactan (AG).  Modifies both the beta-1,6-linked galactan and beta-1,3-linked galactan present in type II AG.
What are the official names of this protein?
Beta-glucuronosyltransferase GlcAT14C, GT14 family glucuronic acid transferase 3, AtGlcAT14C.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: ASTD_SPHAL
Sequence: MSEELLSFEPATGEQLWRGKVSDVDAEVEIARRAWPEWAAKPVTFRTETLRRFADRVKAESEAFADLIARETGKPLWEARTEVESVANKVDISVKAYAERTPNRRIEGAMGLRSAVRHKPHGALAVLGPYNFPAHLPNGHIVPALIAGNSVVFKPSEKTPAVGAKLVELLHSAGVPQEVLRLVVGGPDTGKALAAHPGIDGLLFTGSARTGLALNRQFAGQPGKMLALEMGGNNPIVAWDTADIRTAAILIVQSAFLSAGQRCSNARRLIVKDSLADALIAEVRELANRLIVDHPHADPAPYMGPVIDNEAADGLTESFLVLMSNGGQVIRHMTRPVAGRPFLTPGIIDVTTMAERPDVELFGPLLQVIRVETFEAAIAEANNTAFGLSAALIGGTPQLYDQFWANARAGVINWNRPTNGASSAAPFGGVGLSGNHRPSAFYAADYCAYPVASAESDALRASIGVGLRDPEGSQLVTKKYL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: MOAC_VIBC3
Sequence: MMSQLTHINASGEANMVDVSNKADTVREARAEAYVRMAPETLQLILSGQHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEVQLEALPEQSSVRIESLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIENVRLLEKSGGKSGHFKVDA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PER6_VITVI
Sequence: MGNISPLTGTNGEIR
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 6.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IDI_CLAMS
Sequence: MPQHTELVVLLDDDGETIGTAPKATVHTRDTALHLAFSCHVFDAEGRILVTRRAIGKLTWPGVWTNSFCGHPAPDEDMLEAVHRRAEQELGLTLESVELVLPDFRYRATDAAGVVENEICPVFRAVAATPVDPRPEEVGEYQWVDPEQLIPAVAHTPWAFSPWLTLQLPLLYPEHAAHAGLADAAAVPAA
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIAH1_CAEBR
Sequence: MSNRKGGGGAGDYQEVIESLRRSQLIFEEDENAGPEIPTVVTSSSSASSQRSSASQHHRLNNMVVGGGGRDNEMSNNQNGNTPSVTIPSQCQVMTPRISSPSSVMAPSVTVTSGTVQQGKTFARIQGSSPSNTTHSTPTVAQAMQSVAPHIPIVGAGADDSSAEILSVFECPVCLEYMLPPYMQCPSGHLVCSNCRPKLQCCPTCRGPTPSVRNLGLEKIANTVRFPCKFSNSGCPLNFHHIDKMDHEELCEYRPYSCPCPGASCKWQGALADVMDHLKKVHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFDYNFMLVLEKQEKYDPAQSTQMFYAVVQLIGSKKEADNFVYRLELSANRRRMSWEATPRSIHEGVAFAIQQSDCLAFDTSAAQLFAENGNLGINVTISRIDGQQRRHPNESDAVDVEYD
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  It probably triggers the ubiquitin-mediated degradation of different substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase siah-1, RING-type E3 ubiquitin transferase SIAH1, Seven in absentia homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
Protein: MOAC_BORA1
Sequence: MSDSLPTLSHLDDSGQVRMVDVGDKADADRLAIARAAVRMSPQAYGLLTQPGQGKGEVLNTARVAGVLAAKRCAELIPLCHSLPLAFVGIEFSLDDEGHRVEIRATCRTRYKTGVEMEAMTACSMAALTIYDMCKAADKGIVIEQVRLAYKSGGKSGEWRND
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CHMP7_SCHPO
Sequence: MGKKEKVNALEFSVNKGIFTKTRLKSLYSDFTSLFIKNPEGFLANVNTWREAIETSAWSGKLNSRIILVFDETFESAFSSPALGRPLSLGAVAAYWIQQGVWLRKQDFLNDCKKGNLVREDGFSIFSILRWSFQKLGFQNQASSILSNRSPSGQYVIRKNIEKLACLVHNEAMRRCSSYTSAIYTWDFFQDTFGSLYWEEGKLNKDEMECLLNWMCYQKHVLIFDSKIIKFLPNSQIDAQLASIDKSIDGSVADLIQARASIAQRSEFLNEELEQLSQVLNQAVKKGEKTIAITYLRRKKILSKDLERKVSSRLQLDTIISNIDNAVDNKILLIAMSSGSEALDAILAQMGGTEKVEDVLENVNDTLARSEEIDATIQTYNPQNIDLEDEAVEKEWQDLVAEEQKVEDIVSTLGNVSLKTPSDTFTLTNTDSDKKTSKPEKIQAELVEQ
What is the function of this protein?
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase (By similarity).  Plays a role in regulating nuclear envelope (NE) morphology and nuclear integrity, particularly during spindle pole body (SPB) extrusion or insertion through the NE, and perhaps during karyokinesis (PubMed:28242692).
What are the official names of this protein?
Charged multivesicular body protein 7, Chmp7, ESCRT III complex subunit Cmp7, Cmp7.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_GEOMG
Sequence: MKITKAEVDAVALLARLELTPEETETFTGQMDAILAYVEKLNELDTSGIIPTSHAVPVENAFRDDAVRPSIGVENALANAPDRVEGFFRVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: TPIS_RAT
Sequence: MAPSRKFFVGGNWKMNGRKKCLGELICTLNAAKLPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHIFGESDELIGQKVNHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWCKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKCNVSEGVAQCTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_XYLFA
Sequence: MLILTRRSGETLMIGDQVTVTVLGVKGNQVRVGINAPKHVAVHREEIYHRIQRGDELACSSGTRGDSGSSI
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_BEII9
Sequence: MRVYYDRDADINLVKGKKVAIIGYGSQGHAHALNLRDSGVKEIAIALREGSSTAKKAEAEGLTVKTVVDAAQWADVVMVLTPDELQADIYHQLLAKNLKQGAALLFAHGLSVHFNLIEPRADLDVLMVAPKGPGHTVRSEYKRGGGVPCLIAVAQNASGNAHDIALSYASAIGGGRAGIIETTFKEECETDLFGEQAVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLEDIQGGKFTRDWMLENKVHQTSFKATRAKVAAHPIEKVGAELRAMMPWIGASKLVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: BZP50_ORYSJ
Sequence: MDVEFFADLDLDALLASFSSSAAAAGSGVSGLFAPSPPHDAEAGSPESVSSRRPSPSREAALSEIERFLMEEGPAAEEGVGAEDFFDALLVDGGEEEEEEEGKGSEAGGSTDGDSGKENEVATPDAEKEDVEAEVDGDDPMSKKKRRQMRNRDSAMKSRERKKMYVKDLETKSKYLEAECRRLSYALQCCAAENMALRQSLLKDRPVGAATAMQESAVLTETLPLVSLLWLVSIVCLLPVPGLPNRNPVARSSAGRDLATVTGKKTSSEQQLEETLLLHGRRCKGSRARIKLDTGPFRLAAAAC
What is the function of this protein?
Transcription factor involved in endoplasmic reticulum (ER) stress response (PubMed:21223397, PubMed:22050533, PubMed:22199238).  Acts downstream of the ER stress sensors IRE1, BZIP39 and BZIP60 to activate BiP chaperone genes (PubMed:22050533, PubMed:22199238).
What are the official names of this protein?
bZIP transcription factor 50, OsbZIP50, OsBZIP74.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Note=The bZIP domain is translocated into the nucleus in response to ER stress.
Protein: CYB_RHISO
Sequence: MTNIRKSHPLIKIINHSFIDLPTPSNISSWWNFSSLLGICLILQILTGLFLAMHYTPDTTTAFSSVAHICRDVNYGWMIRYLHANGASMFFICLFIHVGRGLYYGSHTFLETWNIGIILLLTLMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAITHLLFLHETGSNNPSGIPSNTDKIPFHPYYTIKDILGALLLIMVLLTLVLFSPDILGDPDNYIPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALTFSILILLLIPSLHTSKQRSMMFRPLSQCMFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFSLILVLMPLAGIIENSLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL39_METM5
Sequence: MAGNKPLGKKIRLAKALKQNRRVPMFAIARTKGSVKQHPKMRHWRRKNLKK
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: FOLD_RHOPS
Sequence: MTARIIDGKIISADLRGRVAAEVTRIKAEHGITPGLAVVLVGSDPASEVYVRSKHKQTQEAGMASFEHRLPADVAQADLLALIGQLNADPAVHGILVQLPLPKGLDSNAVIDAIDPAKDVDGLNPVNAGRLASGLFALTPCTPLGCIIMAKQVHASLEGMNAIVIGRSNLVGKPLVQLLLNENATVTIAHSRSRDLPALCRQADLVFAAVGKAEMVKGDWIKPGATVIDVGINRTPSPDGGKDKLVGDVAFHEAKDVAGAITPVPGGVGLMTVACLLVNTVRAASAIHGLPKPGV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CSRA_HAHCH
Sequence: MLILTRRVGETLMVGDDVTVTVLGVKGNQVRIGVNAPKEVAVHREEIYQRIQREKSAQAGESDHQDD
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTH_SALPK
Sequence: MTDNRVENSSGRAARKLRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELFFSQPDMAQLGKGMVIPALPNPEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGIADLDQAYLTLEPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFVRFHIPLWVRRTITMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSNATLMGELVNTRRVKQIGWIIVVLVVALNIWLLVGTVMGLS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIVB6_BRUSU
Sequence: MKKIALTALAVFSLAASAAYADVVKVGVIGPFSGPFALQGKNFKAGIDAYMAEHGNKVGDDTVEVVYRDVPQADPAQSKALAQELVVKEGVQYLAGFYFTPDAMAVTPILKQGNVPMVVMNAATSSIVTKSPYVVRTSFTTWQTSTPIARVALDKGVKKVISVVSDYGPGVDAENAFKAAFTDAGGEVVEAIRMPLATNDFSPIMQRIKDSGAQGVFAFLPSDPTTLGFMKAYVDNGLKSSGIQLFAPGDLTQESDLPALGENALGVLTTFHYAVSHDSPENRKFVEEARKAIGNPAELSFPSVGAYDGMHVIYKMIEATGGKKDAAKAVEAVKGMEWVSPRGPVSIDPESRHITQNIYLREVAKADDGTYYNKEIQTFEKQGDPGLKAQ
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 6.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: METK_ACIBT
Sequence: MREYAVFTSESVSEGHPDKMADQISDAILDAILKEDPYARVACETLVKTGAVVLAGEITTTANIDVEAVVRQTVNGIGYHHSDLGFDGSTCAVINMIGKQSPEIAQGVDRQKPEDQGAGDQGLMFGYASRETDVLMPAPISYAHRLMERQAELRRSGALPWLRPDAKSQVTFAYENGKPVRLDAVVLSTQHDPEITQTQLKEAVIEEIIKPIIPAEMFHAATKFHINPTGMFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADKCEIQVSYAIGVAEPTSISINTFGTAKVSDELIIQLVREHFDLRPFGITRMLNLIQPMYKQTAAYGHFGREGSDTAFTWEKTDKVEALKDAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.