PharMolix/UniProtQA huggingface dataset:
Protein: SYFB_RICTY
Sequence: MKFTLSWLKQFLEISASVTEIAEALTDIGLEVEEVIDKATELQKFEVAYIRNIKPHPSADKLKLCDVETKNGILQIVCGASNVRADIKVVLANIGIEIPKGNFKIKESIIRGEKSYGMLCSEEELLLSSDSNGIIELPEYAVVGDNFTRYYGLDDPIFVINVTPNRGDVLGVYGIARDLSAKGLGTLKKLELPEIKSTFFSKIKLNVHDKAACPLFTFREIRNLKNKPSPSWLQQLLKNVGIKTISSLVDITNYIAYSFGQPIHVYDADRIYGALSVGRDCNCKVISYKNHEIATAVLKSSNDTANFYAINGKEYLLTENDLTIKDESGIQGLAGIICGAKSSCNDSTINVILEAACFNARLVAASGRRLKIDTESRYRNERNIDRNFTEKALDIATNLILSICGNCEVSEVVKVGEQELQKIPLDFSVYFLEKITGIKLSIKEIEVILNKLGFITDVKGDIIKVIAPSWRHDINILEDIAEEIVRIYGYDKIESIKLPELHQDNNNLREYKRISSFKRILASQGYDEVVTNSFMSSEDAKLFAELKEELFLLNPMSIDENYMRPTVLPNLISIVSKNLARAIKDMAFFEVGPSFINLNTELTYLTAIISGSFNNKNPHSLGRSYDIFDIKGALEQVIEYAGLSLDKCIVANETVLPQYYHPTRAINIRLGKNLLGHFGQIHPKILKYYDINQEIFAFELNITNLPLIKAKFGKRNELKVSDFQANFRDYSFIVNQDHRVGEIISYINNFNKNLVKSVMLFDIYSGDKLPEGKKSISIKIELQADDRTLSETDLNAFSQDLVESISQKFQGTLRE
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_THENN
Sequence: MSEKLWEKGYTVDEEVEKFTVGDDYIVDMRIIKYDIKASIVHSKMLQRTGLLTQEEQKKIEEALNELLHLVEEGKFQIKPEDEDCHTAIENFLVKKLGETGKKIHTARSRNDQVLTALRLMYKDELKKIKDLVVELQKSLDGFIERFGQIKFAGFTHTRKAMPTDFATWAGALRDALQDDLKLLETVYDIIDQSPLGTGAGYGVPIEVDREFTAKELGFSRVQWNPIYTQNSRGKFEYLLLHVLSQISYDLNRFASDIIFFSLPEIGFLKLPKELCTGSSIMPHKINPDPLELVRAYHHFVVSRMVMAVSLPSNLILGYHRDLQLLKKPVIESIDVVKNILRIMKIIFDRIEVDREKSEDSITEEVLATHRVYELVKKGIPFRDAYRMVAEKYGREKD
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_STAA3
Sequence: MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPSGSIKDQDSIDMANKHGIAMVVTGTRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: EBR_SALTM
Sequence: MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFYFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSPSWKSLRRPTPW
What is the function of this protein?
One of the determinants for resistance to ethidium bromide and quaternary ammonium compounds.
What are the official names of this protein?
Putative ethidium bromide resistance protein, E1 protein.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBC_PINTH
Sequence: MKTLYSLRRSYPVETLFNGTIALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEIVDTFPYFVSGVLHLISSAVLGFGGIYHALIGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGVGAFLPVLKALYFGGVYDTWAPGGGDVRKITNPTLNPSAIFGYLLKSPFGGEGWIVSVDNLEDVIGGHVWLGSICIFGGIWHILTKPFAWARRAFVWSGEAYLSYSLAALSLFGFIACCFVWFNNTVYPSEFYGPTGPEASQAQAFTFLVRDQRLGASVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLSKLRKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: R18AL_ARATH
Sequence: MDEEAAKPRDSTVNQQHQYYYGTFQGVANFPTPTPPPQFMQPQHPITTFPGHAYQNLQGHGGGVNYAQGFPVVVPDYTVVEVRPMIEHELPCCGLGMGWFLFIMGFLFGGIPWYLGAFIVLVTSVDHREKAGYVACSIASVVYLIAVMLGMTGDINIW
What are the official names of this protein?
60S ribosomal protein L18a-like protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: KUP1_CHRVO
Sequence: MSAGYRSMAISASDRERGQQSMAMLVLAALGVVYGDLGTSPLYALQEAFNGDHGVRPTPDNVVGVVSLFLWSLILMVSVKYVMVLMRADNKGEGGILALLAQITGGRSGDGRRVAVGWVLLGLAGAAMLYGDGVITPAVSVLSAMEGLQVATPALAAYVVPATVVILAMLFMIQPFGSGRVGAAFGPILAAWFVAIAALGLAQLWRNPAILQAVNPWHGIAYFQRNGFAGFVSLGAVVLCLTGAEALYADMGHFGARPIRLAWYGLALPALILSYLGQGALLLAHPQLSGRPFYSMVPEWGLLPMVALSTLATIVASQALITAVFSLTHQSAQLGFFPRVKVLHTSGSHKGQIYLPLLNWTLMLATIAVVLGFRESGKLAAAFGLAVSTTMAITTVLFAVLARRRWHWPWWAVALVAGSLFAIDLAFWLANALKFLDGGWLPLLLGLAVFCVMGCWFGGRRLQMRESRGRQLPLEALLSSLGMNPVARIPGVGVFLSERADGTPLVLLHHLKHNQALHETAILLTLQMLDVPRAAGERVSAQWLGQGMARVTARYGYMEEPDVPEAMARAAEALGLPPLEPLSTSYYLGRQTLVAAPGSGGLKRWLVGVFAFLRQNERSATLYFGLPPNRVVELGARIEL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WECG_SALPC
Sequence: MTNNAAAPLYSLRGLPLIGWRDMSHALNYLFADGQLKQGTLVAINAEKLLTAEDNPEVRALIAAAEFKYADGISVVRSIRKKFPQAQVSRVAGADLWEALMARAGKEGTPVFLVGGKPEVLAQTEAKLRTQWNVNIVGSQDGYFTPEQRQALFARIHASGAKIVTVAMGSPKQELLMRDCREVHPHALYMGVGGTYDVFTGHVKRAPKIWQNLGLEWLYRLLSQPKRITRQMRLLRYLRWHYTGDL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: GATB_FRACC
Sequence: MSTVAPAGALPSYSDVLARYEPVIGLETHVELGTASKMFCGCATAFGAEPNTQVCPVCLGLPGSLPVVNEAAVRFAVMIGLALHCEIASWCRFARKNYFYPDMPKNFQISQYDEPLCTNGWLDVEVEGEVHRVGITRVHMEEDTGKSLHVGGATGRIHGATHSLVDYNRAGIPLVEIVTEPDVRSPEVARAYVDELRELIRALGVSDVRMEQGSLRCDANVSLRPRPAPGDPDAPFGTRSETKNLNSLRSVERAVRYETTRQAALLDDGQRIIQETRHFDEASGRTSSGRSKEEATDYRYFPEPDLTPLALPAEYVERLRAGLPELPAARRARLIAEHGYTARDLQDLRNAAVLDLVEETIAAGAAPATARKWWLNELARRASDAGLQPRDLKITPTDVARITALVAAGELTDALARKVIDGVLAGEGTPDEVIAGRGLAIVADDSALTAAVDAALLGAPDIAEKVRGGKVNAVGPLVGAVMKAMKGQADAAAVRRLLLERLGVS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: HIS7_BURM7
Sequence: MRVAQVVRNTSETQISVKIDLDGTGRQKLATGVPFLDHMLDQIARHGLVDLDIEAHGDTHIDDHHTVEDVGITLGQAVAKAVGDRKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQLETVFKAFGRALRMAVELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_ENTBH
Sequence: MSDSSIKMPPVFGKLLLATQAHLGGVKVTKPMKKYIYGERQDKVSVFDLKKTWDKFILAARAFCGLNYGDDVTVISCKTFGKKPVLKFAETTGAKSYTGRFIPGSFTNTTIRNSCEPRLIIVSDPIVDKQAIEEAAKVNCPTIAFCNTDCDLKYVDIAIPLNNRSPKAIGASFFILSRIIRYIKFGTPMDQDIKEVELFFYRDPIELEKLQEDQNEDNYNEIFNKFSNANEDEFGKIIYK
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPH_MOUSE
Sequence: MAPRKNAKGGGGNSSSSGSGSGSGSGSPSTGSSGSSSSPGARREAKHGGHKNGRRGGISGGSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLGLKERSPSERTFPPEEEAETHAELEEQAPEGADIQNVEDEVKEQIQSLLQESVHTDHDLEADGLAGEPQPEVEDFLTVTDSDDRFEDLEPGTVHEEIEDTYHVEDTASQNHPNDMEEMTNEQENSDPSEAVTDAGVLLPHAEEVRHQDYDEPVYEPSEHEGVAISDNTIDDSSIISEEINVASVEEQQDTPPVKKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVNAFEELVRKYPQSPRARYGKAQCEDDLAEKQRSNEVLRRAIETYQEAADLPDAPTDLVKLSLKRRSERQQFLGHMRGSLLTLQRLVQLFPSDTTLKNDLGVGYLLLGDNDSAKKVYEEVLNVTPNDGFAKVHYGFILKAQNKISESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPRETGYTELVKSLERNWKLIRDEGLMVMDKAKGLFLPEDENLREKGDWSQFTLWQQGRKNENACKGAPKTCALLEKFSETTGCRRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETRTWEEGKVLIFDDSFEHEVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI
What is the function of this protein?
Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.
What are the official names of this protein?
Aspartyl/asparaginyl beta-hydroxylase, Aspartate beta-hydroxylase, ASP beta-hydroxylase, Peptide-aspartate beta-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Sarcoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: PUR8_STAAN
Sequence: MIERYSREEMSNIWTDQNRYEAWLEVEILACEAWSELGHIPKADVQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFRELIEQDESITSVLTKEELDECFDPKHHLNQVDTIFERAGLA
What is the function of this protein?
Catalyzes two reactions in de novo purine nucleotide biosynthesis.  Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
What are the official names of this protein?
Adenylosuccinate lyase, ASL, Adenylosuccinase, ASase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: Y494_PASMU
Sequence: MTPNCAKELVTLSAAHKSFKDYKPQNNYDSIVYSDFKEVEELYGEAQSRRMEHLAKQALLDISTHEPVENAVTLTRITIGALKGDETAKAQLR
What are the official names of this protein?
Uncharacterized protein PM0494.
Protein: Y281_MYCPN
Sequence: MKFKYGTVVLGSFLGLSVVLAACGARGKFDQFDDGKIKLASSLTSKAAANALQTIIEKYNIVKSGKDYPIEITQIAGGYDGGRTDLQTRVSVKDKTNFYNLILNYPDLVSVLARSGMELLFDKVNVDKLEPNFLKFNEQISGVAKSGNYGIPVSLSTDILVLNGPVLHYILNSAKKEEANSQVKSQIKTSQIQAKGSLTIDTDENTKSLWEKIQNSAKANGETNQKGRKAAKSNKTALVQLKNGADTTTNEENKDTKTSDDKVKQTWGDYVEKDDGLKNYTFRASVFENWHDFLDFSTRVAKSFTEKVSNITNKKGTDIQGVLGVDSSPNVLFASVFAAGGGNYENFFYKLKDGRADFSNFKNKGSSYQNLQSVFKD
What are the official names of this protein?
Uncharacterized lipoprotein MPN_281.
What is the protein family that this protein belongs to?
Belongs to the MG185/MG260 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y8796_DICDI
Sequence: MITPHNYINNSCTTTITTTTTTTAMNKGGTLFEALVIKKQ
What are the official names of this protein?
Uncharacterized protein DDB_G0290235.
Protein: CLPP3_SYNE7
Sequence: MPIGVPSVPYRLPGSSFERWIDIYNRLAMERIIFLGQEVTDGLANSIVAQLLYLDSEDSSKPIYLYINSPGGSVTAGMAIYDTMQYIKSPVITICLGLAASMGAFLLCAGSKGKRLALPHSRIMIHQPLGGTGRRQASDIEIEAKEILRIKKLLNQIMADRTGQPLEKIEKDTDRDYFMSAEEAREYGLIDQVIAERPV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 3, Endopeptidase Clp 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_SYNJB
Sequence: MSRRGVTVWFTGLSGAGKTTLSCGVAQQLRAWGLPVEVLDGDLVRQHLTKGLGFSKVDREENIRRIGFVAEMLTRHGVIVLVSAISPYRAARQEVRRYIGSFIEVFVDAPLEVCERRDVKGLYRKARAGLIQHFTGIDDPYEPPEQPEVVCKTAEQSIPECIDLVIQSLKSRGYV
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: ATPL_METPP
Sequence: MEHVLGFVALAAGLIIGLGAIGACIGIGIMGSKYLESAARQPELMNELQTKMFLLAGLIDAAFLIGVGIAMMFAFANPFVLK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IHFA_RHORT
Sequence: MSGKTITRAQLSEAVYQEVGLSRNESADLLEMVLNEMSEALVEGDTVKISSFGSFSVREKGERVGRNPKTGEEVPILPRRVLVFRPSQLLKARINDGAVGSQING
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: OR8S1_HUMAN
Sequence: MALGNHSTITEFLLLGLSADPNIRALLFVLFLGIYLLTIMENLMLLLMIRADSCLHKPMYFFLSHLSFVDLCFSSVIVPKMLENLLSQRKTISVEGCLAQVFFVFVTAGTEACLLSGMAYDRHAAICRPLLYGQIMGKQLYMHLVWGSWGLGFLDALINVLLAVNMVFCEAKIIHHYSYEMPSLLPLSCSDISRSLIALLCSTLLHGLGNFLLVFLSYTRIISTILSISSTSGRSKAFSTCSAHLTAVTLYYGSGLLRHLMPNSGSPIELIFSVQYTVVTPMLNSLIYSLKNKEVKGERSLRDSSHLPQLHKGQARWKRPAFTEGRREPGHPELSIPVTPQPQGACACSALRAAPTALP
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 8S1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVB_LEGPA
Sequence: MLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIVQRLEYYSVDSLTKIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDYSEVKGNGIITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HTPX_BRUA2
Sequence: MNMTKTAMLIALMTVMFMSIGYLLGGGGGMMIALVIAVAMNLFGYWNSDKMVLRMYNAQEVDERSAPEYYRMVSGLAANAGLPMPKVYIIHEDQPNAFATGRNPENAAVAATTGLLNRLSPEEVAGVMAHELAHVQNRDTLTMTIVATLAGAISMLGNFAFFLGGNRENGNGVMGVVGTLLAMIVAPFGAMIVQMAVSRTREYAADKRGAEICGNPLWLSSALGRIARGAKVIPNEEAEHNPATAHMFIINPLSGRGADNLFSTHPDTDNRIAALEQMAAEMGIRSAAMTARAAAPSQNSGPWGQRSDNAGGNSNGGSRYRGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FANK1_HUMAN
Sequence: MEPQKIMPPSKPHPPVVGKVTHHSIELYWDLEKKAKRQGPQEQWFRFSIEEEDPKMHTYGIIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGECEYSPLVSVSTTREPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLLEERKKKQRPKKSCVC
What is the function of this protein?
Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis.
What are the official names of this protein?
Fibronectin type 3 and ankyrin repeat domains protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium.
Protein: ATPA_CHLAD
Sequence: MTTITEELIARLKQGIISGVDLQPRQVNVGTVIAVGDGVARLSGLDQVVASEIVEFPPKAGRNESIYGIALNLEQDSVAAIILGDDESIEEGDLVTSTGRVISVPVGQGLLGRVVNPLGQPIDGKGPIQYEKMRPIERIAPGVITRKSVDTPVQTGIIAIDALIPIGRGQRELIIGDRQTGKTAVAIDTIINQKGQGMVCIYVAIGQRRAQVAQVVGTLEKYGAMEYTIVVSATASESAALQYIAPYAGCAMGEEIMENGVMLNGQLVKDALIVYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLNEEYGGGSLTALPVIETQANDVSAYIPTNVISITDGQIYLEADLFNAGQRPALNVGISVSRVGSAAQTRAMRAVAGKLKGELAQFRDLAAFAQFASDLDATTKAQIERGQRLQELLKQPQFQPLAVEDQVAVLYAATNNYLDDVPVAMITKWRDDFLAFLRTAHPEVRKLIYDNRLDRKFPTPEVKEALEAAIKEFKATSNYS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GAI1_VITVI
Sequence: MKREYHHPHHPTCSTSPTGKGKMWDADPQQDAGMDELLAVLGYNVKASDMAEVAQKLEQLEEVIVNAQEDGLSHLASETVHYNPSDLSNWLGSMLSEFNPTPNCALDNPFLPPISPLDYTNCSTQPKQEPSIFDSPSLDYDLKAIPGKALYSHIEQPPQQPPAPPLYQRDNKRLKPTTSATANSVSSVIGGWGVPTESARPVVLVDSQETGIRLVHTLMACAEAVQQENLKLAEALVKQIGFLAVSQAGAMRKVATYFAEGLARRIYRLYPDKPLDSSFSDILQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMKQGMQWPALMQALALRPGGPPSFRLTGIGPPSTDNTDHLHEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRDGESVAVNSVFELHSLLARPGGIERVLSAVKDMKPDIVTIVEQEANHNGPVFLDRFTESLHYYSTLFDSLEGCGVSPVNTQDKLMSEVYLGQQICNVVACEGPERVERHETLAQWRARLGSAGFDPVNLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQLANKPALPSSTPASN
What is the function of this protein?
Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway.  Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes.  Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway.
What are the official names of this protein?
DELLA protein GAI1, Gibberellic acid-insensitive mutant protein 1, VvGAI1.
What is the protein family that this protein belongs to?
Belongs to the GRAS family. DELLA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ANMK_KLEP7
Sequence: MRSGRFIGVMSGTSLDGIDVVLATITENMVAQQASLTWPIPHAIKEEILAICQGQSLTLSQLGRLDTRLGRLFADAVLALMRQESLKPTDVIAIGCHGQTVWHEPQGEAPHTLQIGDNNQIAAHTGITVVGDFRRRDMALGGQGAPLVPAFHHALLAHPVERRMVLNIGGIANVSLLAPGQPVRGYDTGPGNMLLDAWIWRQKGKPYDKDAQWASEGKVLLPLLQDMLSDPWFALPAPKSTGREYFNYGWLEQHMARYPGLRGEDVQATLAELTAVTISEQVLLSGGCERLLVCGGGARNPLLMARLAALLPGTEVSTTDEAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASEASVLGAIFPANPPQNRS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RM49_MACFA
Sequence: MAVTMFRAALRGWRTDVQRGCGLRLLSQTQGPPDYPSFVESVDEYQFVERLLPATRIPDPPKHEHYPTPSGWQPPRDPPPNLPYFVRRSRMHNVPVYKDITHGNRQMTVIRKVEGDIWALQKDVEDFLSPLLGKTPVTQVNEVTGTLRIKGYFDQELKAWLLEKGF
What are the official names of this protein?
39S ribosomal protein L49, mitochondrial, L49mt, MRP-L49.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL49 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DRRB_STRPE
Sequence: MTTSPGTVESTTPVSGQLRTVLSAGERPARATAVSATLTHLWRAMMAFKHFPVQLIDIVLMPLIFLLMFTYLFGGAFADSTEEYLQFYLPGVTVQAVVMMTVYTGTSLNTDIHKGVFDRFRTLPFWQPATLAGSLLGDVLRYVVALATTVSLGLLLGFRADGGFLGVVGAMLVLIVFGFSVSWIFAALGVVASEPERVSGTSMIVLYPLLFMSNIFVMPETMPGWMQAIVDANPMSHAATASRELMHGTAGFWDVGLVLCVSAGLVAVFAPLTMRLYRNKNAH
What is the function of this protein?
Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Daunorubicin/doxorubicin resistance ABC transporter permease protein DrrB.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.