PharMolix/UniProtQA huggingface dataset:
Protein: SPC42_YEAST
Sequence: MNGSPTPKRYSSKSSRLYDDYYNIPYQYSNPTPMNRDYNDVGSRINADKLVPEEYKRNTEFINKAVQQNKELNFKLREKQNEIFELKKIAETLRSKLEKYVDITKKLEDQNLNLQIKISDLEKKLSDANSTFKEMRFPKVKDPMVDDDPVSENYDQINVPKHRAPDATGNPRTTNKVSNTSDQDSRLKAIERTLSVLTNYVMRSEDGNNDRMSPLPSPLNTILPINNRLNFQEPKRYNPTVKVNPSDDDIMMYESAELKRVEEEIEELKRKILVRKKHDLRKLSLNNQLQELQSMMDGDDNIKLDNVSKHNHATHRHSSQSSRDYSPSSDACLECSNDLYEKNRVKPENNMSETFATPTPNNR
What is the function of this protein?
Forms a polymeric layer at the periphery of the spindle pole body (SPB) central plaque which has an essential function during SPB duplication and may facilitate attachment of the SPB to the nuclear membrane.
What are the official names of this protein?
Spindle pole body component SPC42.
What is the protein family that this protein belongs to?
Belongs to the SPC42 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: PTP11_STYPL
Sequence: WRMIWEHNTRNIIMLTQTVEKGKIKCDHYWPFDNEPIVSGDITIQMTSESMLPEWTIREFKITHGANTRRVRQFHYTVWPDHGVPETTETLVKFIRYVRRTIDGEAKHTGPTIV
What are the official names of this protein?
Tyrosine-protein phosphatase 11.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: SYFA_ESCF3
Sequence: MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4M_DEBHA
Sequence: MTMLFVIFSGLTSMTSRLVNSMSKHMFTVASMLMAMPTLYDWEEIDVYYTSDGMADVLMLLTMYMLPLSMISNWNNMKSTLYFELVLNLGMMLLINFMCQDMTSFYMYFEASLAPLFMLMGLYGAANRDKAADYVLMYTLFSSLFMLLAMALYEVMLDNTDYQATSLLVLSLDLQCMLFLAMSMGIAVKTPLAPLHTWLPVVHSESPLAGSMLLAGMILKLAVFAMIRLILPTLSDASVTYTPFVYVMCVMTMMYTSIITLRQTDLKVIIAYSSISHMAVCMLGMLSNTMTGITGSLVLCIAHGFVSPGLFMMVGGMLYDRYHNRLMYYFQGLISYMPYLSVYFMMLSFCNMGTPLSINFIGEMLSLTGAINRAPVLGAMAALSVLLSACYQMKLTNRLTGGIKTPYMSLTSDCTYRETVLMITLIVPTMFLGFFPSWVMDFLWDAPNLLYMFMVYRTFIKMSIPWL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: URE22_BRUAB
Sequence: MAKEPTEAAHPQPEQTKTNHKAHRPVGGYVLAKDPIEINQGRPRTTLTVRNTGDRPIQIGSHFHFFEVNRYLEFDRSKAFGLRLDIPANTAVRFEPGDEKEVTLVPFAGKRFIFGFNNLVDGWSGDGPTPDYQPNREIAAERAEKLGFKSCKSGGKDAK
What are the official names of this protein?
Urease subunit beta 2, Urea amidohydrolase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBL_SCHPO
Sequence: MPSDCKYSVDTELVHVEGNEDQYHASSVPIYQSATFKQPCLEHMGKFDYTRSGNPTRSVLQVHLAKLMKAKHAFVTSNGMSALDMILRCCKSNSHVVAGHDLYGGSDRLLSFNQRQYGFKVDNVDTSDLAAFEAALRPDTNLVLIESPTNPRISICDIRAIVKITRSKAKDALLVMDNTMLSPVLCNPLDFGYDIVYESATKYLSGHHDLMGGVIATKSDEIAKSVFFNINAMGAAMAPFECFLLLRGIKTMGLRVERAQQNAIEIAKFLKSKGLQVNFPGLDPDAKSTAIFYSFARGPGAVMSVFTGDVEVSKTIVNTTKLFEISVSFGAVNSLISMPAYMSHASIKKEVRDARGLSEDLIRICVGIENVDDLKADLENALAQANFKQN
What are the official names of this protein?
Cystathionine beta-lyase, CBL, Beta-cystathionase, Cysteine lyase, Cysteine-S-conjugate beta-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYR_METS4
Sequence: MNIFAAFEERIGEALATLTRAGQLPEGLDLGRVVVEPPRDPGHGDLATNAALVLAKEARTNPKALAELLAAELRQDPRVTEASVAGPGFLNLRLAPEVFAEVVRAALASGEAFGRGARRPGLVNVEYVSANPTGPMHVGHGRGAVFGDALANLLAASGREVVREYYINDAGAQVDVLARSAYLRYREALGDAIGAIPEGLYPGDYLKPVGRRLAETHGRALLREPESAWLPVVRDFAIAAMMDLIRDDLAALGIRHDVFFSERTLQGGGDGGAVGALIAELREKGLVYVGRLPPPKGQLPEDWEDRDQTLFRSTAFGDDIDRPLLKSDGTYTYFASDIAYHASKVARGATDLIDVLGADHGGYVKRMQAAVRAVSDGRASLDVKLCQLVRLLRGGEPVKMSKRAGEFVTLREVIDEVGRDPVRFMMLYRKNDATLDFDLAKVVEQSKDNPVFYVQYAHARTASVFRQAREAFPGEDLSPQALAGADLSLLRDSGEADIMRLVAQYPRVIEAAGSAHEPHRLAFYLYELASAFHSFWNKGKDLPQLRFVNQTDRKSTLSRLALVAALRGVLASGLGILGVTAPDEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3C_CARPA
Sequence: MFLLYEYDIFWAFLIISSAIPILAFLISGVLAPINKGPEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSVFIEALIFVLILIVGSVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ATPE_THESQ
Sequence: MKVKIVTPYGIVYDRESDFISFRTVEGSMGILPRRAPIVTQLSVCDVKIKSGDDEYHLKVAGGFLLCDGKDVIIITEEAGREEDISPDRFMEARERVERVRRFFQSSL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRE_CHRSD
Sequence: MTAQLQPYQREFIEFAIDEGVLKFGEFTLKSGRISPYFFNAGLFKSGRALARLGRFYAQAIAHSGLEADVLFGPAYKGIPLATTTAVALADHHDRDLPFAFNRKEAKAHGEGGNIVGAALAGRVLIIDDVITAGTAIREVMQLIDAAGAEAAGVVIALDRQERGQDENGLKAQSAIQEVTSQYGMPVVSIVTLDQVLAYLETRQSQGDESDQSLRQHADAIRAYRDRYGVRLDG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CYOE1_SHEB8
Sequence: MAKPLSITSSLPTFSVTWRAYFEMTKPKVVALMLLTVLVGMCLAVPHAVPVQPLLAGMLGIAMMAGSAAALNHLIDRRIDGLMARTYNRPLPKGRISATRALIFAASLGSLGFIVLYSLVNPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAMPPLLGWTAVTNEFHGHALLLVIIIFTWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTVLLAIACLLPVLVGMCGPVYFVCSSLLSTGFIYKAWQLKYRDHDGSAMQVFRFSIYHLMLLFMALLLDHYLWN
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOCD_CERSK
Sequence: MSLDQAIPEALQALRTRFGAAVRAEQATGEAFPVLWLDASVWEAAHRFLREEIAAPFPLLADLWAIDESLRQHRTGQPASRITLCSHLVSLVRNADLRLKLATDGRAPSIAGVYANADWYEREAHDMFGLDFGRETRRILMPPTWEGHPLLKTHYARATEKPPFVLTDRLFEAEERATITDPDLLGLPTLRDGEELMVLNFGPHHPSTHGVFRILLGLDGEEVVWAWPDIGYHHRGAEKMAERQTWHGFIPYCDRIDYLGGVISELPYLLAVERLCGIAVPPRAQMIRVMLCEFYRIMNHLLFYGTMAQDVGAMSPVFYMFTDREKGHEILNAITGARMHPAFFRIGGVAMDLPNGWDAMVRGFLDWMPARLDEYERMVLRSELFRARTVGVGAYDTDMALTWGTTGPGLRATGCDWDLRKLRPYSGYEQFEFEVPLGQRGDIFDRTRVRADEMRESLKIIRQCLENMPEGPVKADHPLTTPPPRGAMQKDIETLIAHFLQSSWGTVVPAGEATGQIEGHRGLTQYSVVSDGGTQSYRTRIRTPSFAHLQMIPKIVPGMTVADLVAHIASIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: METE_LACLA
Sequence: MTMKKSIIAFPRIGSNRELKFALEKYFRKEITEEELQTVAKEIRLENWKSQKEAGIDSPISNDFSFYDQTLDLSIALGAIPGSYKNLELSELDTLFALARGFQDEQNDVKARPMKKWFNTNYHYLVPEINKDTIIKANFSKLLNEYKEAKSAGFETRPTIIGPYTFLVLADYKSGATKDTVLSDVIVAFQTLLKELNQLGVEWLQIEEPALVLDQTEEEKKLFVSIYEELLKSKNNLNILLQTYFGDVRDSYKEIIKLDFDGIGLDFIEGRDSLALIQKYGFPKKKILFAGLVNGKNIWRNNYQKTLELLTALDEVADIVINTSCSLQHVPVTIKNETKLSKEILKHFSFATEKLNEIDEISDIYFNKNTSFLKKNVELFENERVRENSKLKQKLDKLTEKDFTRQPSLVERRASQSQSLNLPVLPTTTIGSFPQTAEVRKVRLQNKRGELRQADYDTFLEEKIKECLKLQEDIGLDVLVHGEFERNDMVEYFGEKLEGYVFTQKAWVQSYGTRCVKPPIVWTDVTRPEAMTVRWSAYAQSQTSKPVKGMLTGPVTILNWSFPREDISLKASTLQLALAVQEEVLDLEKAGIKIIQIDEAALREKLPLRKSDWYKEYLDWAIPAFRLVHSKVKPETQIHTHMCYSEFEDIIPSIDAMDADVISFEASRSELSIIDALKAHHFKTLVGPGVYDIHSPRIPSVKEIQNQLEKILDKLPIEQVWVNPDCGLKTRGNAETIPSLRHLVEATRVLRKEKVVYDK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: MRAZ_HAEIG
Sequence: MFRGATAVNLDSKGRVAIPTRYRAEILEKNQGKMVCTVDIRQPCLLLYPLMNGKKSNKKLLALSNFDPTQRRLQRVMLGHATECEMDAQGRILFSGPLRQHAKLEKGLMLVGQLNKFEIWSDVEWHTQIAEDIEIGSSADFAADALNDFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FIXA_BRADU
Sequence: MHNIVCIKQVPDSAQIRVHPVTNTIMRQGVPTIINPYDLFALEAALGLRDRFGGEITVLTMGPPSAEESLRKALTYGADRAVLLTDRCFAGSDTLATTYALATAIRKIGKEYGPANLIFTGKQTIDGDTAQVGPGIAKRLGVGQLTYVAKVRSVDVANETIEAERRSEGGVQVLHTRLPCLITMLEATNQIRRGAMADALRAARAKIVKWSAQDAGVEDISKCGLKGSPTVVKRVFAPPARAERAALVESAEQPAQALIDAIFLNQPKLETDLATLARDARSGLSGQC
What is the function of this protein?
May play a role in a redox process involved in nitrogen fixation.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: RL9_ENDTX
Sequence: MKVILKSDIANVGRQGEIKEVSAGFARNYLIPQSLVMEANDLNLKIWKRERGILEKHREEIINSAREIAFKMEASKFTAKVKIGENGKIFGSITTATLVKIFEDNGFKVNKRDIILSDNIKEIGDHEISVRFHPEVVAKIKLSVINEKE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RS15_STRZT
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIKQHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RS16_DESAH
Sequence: MSVKIRLARRGAKKKPFYRIVAADVESPRDGKFLESVGTYDPMVEPAAIILNEERIRYWMGEGATPTTTVKSILKKQGFSSNPA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FLGG_ECOLI
Sequence: MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGFFQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVTQQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGYVETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL
What are the official names of this protein?
Flagellar basal-body rod protein FlgG, Distal rod protein.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: FMT_RICRH
Sequence: YFSYNDKIIKILEAEYLNADHHFTSGTVISDKLEIACGSGILRVKKLQQESKKALNIEEFLCGTNILKDTVLK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: YODT_BACSU
Sequence: MSSYLIKPELSSAYPVVSYAKGSYVYDQTGKKYLDGSSGAVTCNIGHGVRDVTEKLKEQLDQVSFAYRSQFTSEPAEQLAALLAQELPGDVNWSFFVNSGSEAIETAMKIAIQYWQEKKQTQKSIFLSRWSSYHGITLGALSLSGFYERRYRFTHLIERYPAISAPHIYRLNHETEEDFVQTAADELDTMIKRIGSQFIAGFVAEPIIGAAGAAITPPPGYYERLSEVCRTHDVLFIADEVMTGLGRTGRMLATEHWDTVPDIAVLGKGLGAGYAPIAAAVVSDSIIETIKQGSGVIMSGHTYSAHPYSAKAALEVLRYVLKHGLIKQSEKKGAVLKKKLDEAASQSGIIGEVRGKGLLLGIEFVADQKTKKVFPPEQAITQLIVSEAKKRGLIVYPSKAGIDSGEGDAVIIAPPFTISDGEMEELISIFSETVAAVEKNLKKD
What are the official names of this protein?
Uncharacterized aminotransferase YodT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: Y2137_SYNFM
Sequence: MNRWARWPLIILIGILGISAVVILSSLASVDYLINIWWFDSLGYGLYYWLRLLYRYIVFGAVTLLFFLIFFLNFWVASRYVGNVPPAPSKFRIAALDRYLNVVRMFRSGSLWVYTPLSLILAVIIALPIFEKWEAFLLYVAGPKTGVPDPVYGKDISYYLFSYPIYTLVQRRLLIAFVLLLVGLVALYLLERRLLARQEQPIPAGARLHLSILILLIFLIETWDYVLQRYELLYSEAHMPLFYGGGFVEMYVIWALIWLTLFFLMGTAFSMIAFIQTRKGLKPLVVFAVGFVLVLGLRYSAFLPATVEKLVVKPNEVSRERDFIVNNIKATLSAYNLNTVQTRDFTPARTAADVASPKVKAQLRNIPVWDGELLDDVYKQLQQLRTYYTFPSVDVARYTVNGMPQQVFLSVRELDYTLIPEAARNWVNEHLSYTHGYGAVMTPASQGGDEPMTWFIKGIPPESEYGFRIEQPGVYIGLGSYTYVIAPNDAGEIDYPKGNSNTMVSYKAEDGVPLSSFLRRILFAYHFGDRNLLFTTKTTPDSKILFRRNLLERIRVLTPFLLLDGDPYAVVTPGKLYWIQDAYTTSEFYPGATPTLWGRDRFNYIRNSVKIVVDAFSGKVEYYVFEPGDPIVRAYSRIYPGVFRNADQMPPELKAQVRYPQDIFEIQMNIYAKYQQTDPEVYYQQEDMWEPAKTFQDRTPVTIKPYYVTLDLIDPSRFDFLLLAPMSPKGRDNLRALALAGSDPPHYGKIIVYNFPKGELIYGPSQIYALINQDTRISEQFTLWDQVGSQVARGKMIILPISNMILYIQPVYLKSATKLKIPELKRIIMSQGQIVVMEPSLEEAYAKLQERIKLEIDRVDKRFAPLLPGSPAGR
What are the official names of this protein?
UPF0182 protein Sfum_2137.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NANT_ALIF1
Sequence: MEAQSFGTLNYIALFAYLGAIMAVGVYFARRQKSADDYFKAGGRIPGWAAGFSVFATTLSSITFMSIPAKAYTSDWTFLIGQYVAIAILPIVFWFYIPFFRKLNLTSVYEYLERRFDVRMRLFGSISFMLFHIGRIAIVTYLTALALMPFIDISPLMIVFLIGVLCIIYTFLGGIEGVIWTDVIQGVMLSVAAILIFVVICFNVDGGIVEVFSMSNQADKYFPAEQFSWSWTDSTIPVLMIGFFFASLQQFTASQDVVQRYIVTDNIDETKKALITNAKLVACVPIFFFAVGSALFAYYTQNPELLPENFNTGGILPFYVISQMPVGVAGLIIAAIFAASQSSISSSLNSIAACFTSDIYEKVSKNPTSEQKLRIGRTLTVVAGLLGVVASTYLIMSNESEIWDAFNSLLGLMGGPMTGLFMLGIFVRRANANSALLGVVASIATVLWVRSATDLNFFFYGVIGTLMVVIVGYLTAPMFKNNLNSDEIDELSATKEKRSTTAEKA
What is the function of this protein?
Seems to be involved in N-acetylneuraminate transport.  Complements an E. coli nanT deletion mutant.
What are the official names of this protein?
N-acetylneuraminate transporter.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YJEN_ECOLI
Sequence: MDDTSRDPAITEDEIRALQFSAGDVAEIEQTILSFVDACHTRKVAMVVGSTINTLKDRDGKRWGNLPDIYCAYLIRCLVFRGELVGYGDLFRMRYSEIKRPVTL
What are the official names of this protein?
Uncharacterized protein YjeN.
Protein: ZIC2A_XENLA
Sequence: MLLDAGPQFPALGVGTFARHHHHHHHHHAAVAAAAAAAAEMQERELSLAQNTFVEPTHMAAFKLNPGGGSGGGSGGGGGGGGAGPNGGAGASGPHDLSPPGQTSAFTSQAGYPTSALAPHSAYSGAAAFNSPRDFLFRGRGFAEGSAAAGGGQHGLFGPPAGSLHHHPHHHHQLSHAEHPQGHLLFPGIHDQHAAASQNTLGGQMRLGLPGEVFGRTEQYRQVSSPRGDPYTAAQLHNQYSPMNMGMNMAAHHHHHHHHHPGAFFRYMRQPCIKQELICKWIDPEQLNNPKKSCTKTFSTMHELVTHVSVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPNSETQNPNLSPAAAAVSAVHNVSSGASGALASNFNEWYV
What is the function of this protein?
Transcriptional repressor that inhibits neurogenesis and induces neural and neural crest differentiation.  Regulates anteroposterior patterning in early development by inhibiting expression of the nodal genes through the inhibition of vegt.  Required for gastrulation movements and for proper anterior neural and axial development.  May also act as a transcriptional activator.  May bind to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'.
What are the official names of this protein?
Zinc finger protein ZIC 2-A, Zinc finger DNA-binding protein fZic, Zinc finger protein ZIC 2, XlZic2, xZic2, Zinc finger protein of the cerebellum 2-A.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TIP39_DANRE
Sequence: MALSLPPRPALLFLVLMSVTLMASAFPQPQLRPLQSNLPAIGQEDSKGEQWEVVYPSISLRDWSIQMLTAPDFGAAKTGREQLVADDWLPLSQSQMEEELVKGWTGDWPSRVGHQQKRNIVVADDAAFREKSKLLTAMERQKWLNSYMQKLLVVNSK
What is the function of this protein?
Plays a role as a potent and selective agonist of pth2r resulting in adenyl cyclase activation and intracellular calcium level elevation.
What are the official names of this protein?
Tuberoinfundibular peptide of 39 residues, TIP39, Parathyroid hormone 2.
What is the protein family that this protein belongs to?
Belongs to the parathyroid hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRE_XANCP
Sequence: MTDHRTRFLQLALDADALRFGEFTLKSGRLSPYFFNAGRFDSGAKTAQLAQCYADAIDAAGVEFDLLFGPAYKGIPLATALACAYAGRGRDLPLAFNRKEAKDHGEGGTLIGAPLQGRKVLIVDDVITAGTAIREALGIIRAAGGTPSGIVVALDRQEIASEQDRRSAAQAVAAEAGIPVIAVANLADLLAFAAGNADLVGFREPLLAYRGRYGTDTTG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: YCJF_SHIDS
Sequence: MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDEAQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNACQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRVFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETL
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ELFN1_HUMAN
Sequence: MAGRGWGALWVCVAAATLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGQGRRGHRSILSKLQSVCTEDSYAAEVVGPPRPASGRSQPGRSPPPPPPPEPSDMPCADDECFSGDGTTPLVALPTLATQAEARPLIKVKQLTQNSATITVQLPSPFHRMYTLEHFNNSKASTVSRLTKAQEEIRLTNLFTLTNYTYCVVSTSAGLRHNHTCLTICLPRLPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRRRRRQEEKHKKAASAAAAGSLKKTIIELKYGPELEAPGLAPLSQGPLLGPEAVTRIPYLPAAGEVEQYKLVESADTPKASKGSYMEVRTGDPPERRDCELGRPGPDSQSSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGPVSVAEPPLVLLSEPLAAKHGFLAPGYKDAFGHSLQRHHSVEAAGPPRASTSSSGSVRSPRAFRAEAVGVHKAAAAEAKYIEKGSPAADAILTVTPAAAVLRAEAEKGRQYGEHRHSYPGSHPAEPPAPPGPPPPPPHEGLGRKASILEPLTRPRPRDLAYSQLSPQYHSLSYSSSPEYTCRASQSIWERFRLSRRRHKEEEEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS
What is the function of this protein?
Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment.  Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity).  Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
What are the official names of this protein?
Protein ELFN1, Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1, Protein phosphatase 1 regulatory subunit 28.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Localizes to excitatory synapses onto somatostatin (Sst)-containing oriens-lacunosum moleculare (O-LM) interneurons.
Protein: MIAA_HYDCU
Sequence: MQSMNVAQLIEQKICLAIMGPTASGKSGLTMALAKHLPIEIISVDSALIYRGMDIGTAKPTLDEQVAVPHHLIDILDPTESYSAADFVEDVHELVKEIFARGNLPVLAGGTMMYFNALQQGMAKLPSADEAIRAKIHQAWQANPAAVHAQLKQVDPEAAERIHQNDPQRLIRALEVYEMTGKPLTQLQREGQQEGLTEFKLAKVALIPEDRKKLHEQIAVRFHEMLNNGFLKEAEKVFSLDGLSADLPAIRSVGYRQAWLFFAQEYDYDTFVEKSIVATRQLAKRQITWLRKEQDLLVLDPFKTNVDDRVEAVLDYLSALTKNA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: FXL22_BOVIN
Sequence: MHITQLNRECLLHLFSFLDKDSRKNLARTCPQLQDVFEDPALWPLLHFRSLTELKKDNFLLSPALRSLSICWHSSRVQVCSIEDWLKSALQRNICSRHESLVNDFLLQVCDRCPNLASVTLSGCGHVTDDCLARLLRCCPRLRALHLENCARVTNRTLTAVAAHGRALQTLHVDFCRNVSAAGLRRLRAACPRLTLRAEHSAAMIPDQLPRGPHAPGAALRKLLLR
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC) (By similarity).
What are the official names of this protein?
F-box and leucine-rich protein 22.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line.