PharMolix/UniProtQA huggingface dataset:
Protein: MBOA2_ARATH
Sequence: MELLDMNSMAASIGVSVAVLRFLLCFVATIPISFLWRFIPSRLGKHIYSAASGAFLSYLSFGFSSNLHFLVPMTIGYASMAIYRPLSGFITFFLGFAYLIGCHVFYMSGDAWKEGGIDSTGALMVLTLKVISCSINYNDGMLKEEGLREAQKKNRLIQMPSLIEYFGYCLCCGSHFAGPVFEMKDYLEWTEEKGIWAVSEKGKRPSPYGAMIRAVFQAAICMALYLYLVPQFPLTRFTEPVYQEWGFLKRFGYQYMAGFTARWKYYFIWSISEASIIISGLGFSGWTDETQTKAKWDRAKNVDILGVELAKSAVQIPLFWNIQVSTWLRHYVYERIVKPGKKAGFFQLLATQTVSAVWHGLYPGYIIFFVQSALMIDGSKAIYRWQQAIPPKMAMLRNVLVLINFLYTVVVLNYSSVGFMVLSLHETLVAFKSVYYIGTVIPIAVLLLSYLVPVKPVRPKTRKEE
What is the function of this protein?
Lysophospholipid acyltransferase with broad specificity (PubMed:18154737).  Mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity) (PubMed:18154737).  Catalyzes the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity) (PubMed:18154737).  Can convert lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity) (PubMed:18154737, PubMed:24189065, PubMed:25268378).  Exhibits preference for C18-unsaturated acyl-CoA when transferring an acyl group to lysophosphatidylcholine (PubMed:24189065, PubMed:25268378).  Can also utilize lysophosphatidylglycerol (LPG) as substrate in vitro (PubMed:18154737).  Has neither activity towards lysophosphatidic acid (LPA) nor lysophosphatidylinositol (LPI) (PubMed:18154737).  Lysophospholipid acyltransferases catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (PubMed:18154737).  The primary function of the Lands cycle is to provide a route for acyl remodeling to modify fatty acid (FA) composition of phospholipids derived from the Kennedy pathway (PubMed:23150634, PubMed:22932756).  Is involved in PC acyl editing and phosphocholine headgroup exchange between PC and diacylglycerols.  This processes control the majority of acyl fluxes through PC to provide polyunsaturated fatty acids for triacylglycerols synthesis in seeds (PubMed:22932756, PubMed:24189065).  Involved with LPCAT1 in the direct incorporation of newly synthesized fatty acids exported form the chloroplast into PC through acyl editing (PubMed:31511316).
What are the official names of this protein?
Lysophospholipid acyltransferase 2, AtLPLAT2, 1-acylglycerophosphocholine O-acyltransferase, 1-acylglycerophosphoethanolamine O-acyltransferase, 1-acylglycerophosphoserine O-acyltransferase, Lysophosphatidylcholine acyltransferase 2, LPCAT2, Lysophosphatidylethanolamine acyltransferase, LPEAT, Lysophosphatidylglycerol acyltransferase, LPGAT, Lysophosphatidylserine acyltransferase, LPSAT.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LEG4_CHICK
Sequence: MSCQGPVCTNLGLKPGQRLTVKGIIAPNAKSFVMNLGKDSTHLGLHFNPRFDAHGDVNLIVCNSKKMEEWGTEQRETVFPFQKGAPIEITFSINPSDLTVHLPGHQFSFPNRLGLSVFDYFDTHGDFTLRSVSWE
What is the function of this protein?
This protein binds beta-galactoside.  May participate in host antiviral defense through specific interaction with glycans on the viral envelope glycoproteins.
What are the official names of this protein?
Beta-galactoside-binding lectin, 14 kDa lectin, C-14, Galectin CG-1B.
Protein: SECD_RICTY
Sequence: MQNLPKWKIVLSIICTVFAIICALPNFIQINWKFLPHDSVNLGLDLRGGANLLLDVDFDTYLNDSMENIADTLRKNFREHKIGYKNLLVRHNNIQLEVRSTEVLKSLKKIIHKIDPEIIIEVNKNKIKLRYSESRLNDLLNKVVEQSIEIVRMRIDSTGTKEPILQRQGNKHILLQVPGVDNPSYLKNILGKTAKLTFHLVDENANIEEAIKGHIPLDSMLIKGDSEHHGEYYIVIKKKVLLSGTHLTKASASFDQNSQPMVAFSFNNLGSKIFTEITKNNTGKRLAIVLDNKLLSAPMINGAIIGGDGIITGNFTIESANELALLLRVGSLPTPLKIIEERSIGPNLGADSIESGKKAGLIGFTAVCIFMILSYGVIGLFANIALILALLYILALLSLFQATLTLPGIAGIILTMGMAVDANVLIYERIKEELHKGVSNLYAIRTGFESAFATIIDSNLTTLIVAFALYIFGVGAIKGFAVALTIGIISSMFSAIIITKLLIDIWVKYFKPEKLGLL
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL35_STREM
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHLRKAGMVHAGDFKRIKAMVTGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MNMG_BORAP
Sequence: MDFDAIVIGGGHAGIEAALAISRLNFKTLMITQNLDTIGKLSCNPAIGGLAKGNMVREIDALGGEMGRIIDFSMIQFRVLNKSRGPAVQAPRAQADKLMYQTKAKETLERQDNLDLFQDTVVDFLLNSMRNEIEGVVTERGNKFRSSVVVLTTGTFLRGKIFIGEYRANMGRLAEFSAYGLDKTLLGLGFEMGRLKTGTPARIHRKSVDFSKTEVQFGDSDIIPFSFSNGKLDKSQLSCYVTYTNKRTHEIISENMHLSPLYSGEIVGNGPRYCPSIEDKIVKFKDKDRHQIFIEPEGFNTEEMYLNGLSSSLPENVQQKLINSIEGLEHAVITRPGYAVEYDYINPIELYPSLESKRVKGLFIAGQTNGSSGYEEAAAQGLMAGINAALRLQNKKPMILTRTSSYIGVLIDDLVTKGTKEPYRMFTSRAEHRLNLRHDTSDKRLIKIGYDLGLVDEERYSKYLFKKRRVEEIKELLKQRRLSLKDIADEQLKKHVNKDFYHILKDPSISLDNLIKIDPSLSDSKVILEQVELDIKYEGYINRQKDLIKKLHNLELVKLPFDFNYGIIEGLSREAREKFSKVQPATLAQASRIPGIRNTDITVLFIYFSNPKNKVVLNFSV
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYOC_RAT
Sequence: MPSCAYCCSCGPKMPALQLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPSESSCPREDQAMSAIQDLQRDSSIQHADLESTKARVRSLESLLHQMTSGGVTGTQEVQEGLQGQLGALRRERDQLETQTRDLEVAYNNLLRDKSALEEEKRQLEQENKDLARRLEGSSQEVARLRRGQCPSTHHPSQDMLPGSREVSQWNLDTLAFQELKSELTEVPASQILKNQSGHPRSKEGDKGCGVLMWVGEPVTLRTAETITGKYGVWMRDPKPTHPYTQETTWRIDTVGTGIRQVFEYSQISQFEQGYPSKVHVLPQALESTGAVVYSGSLYFQGAESRTVLRYELNTETVKAEKEIPGAGYHGQFPYAWGGYTDIDLAVDESGLWVIYSTEETRGAIVLSKLNPENLELESTWETNIRKQSVANAFVICGILYTVSSYSSVHATINFAYDTNTGISKTLTIPFKNRYKYSSMVDYNPLERKLFAWDNFNMVTYDIKLSEM
What is the function of this protein?
Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration.  Promotes substrate adhesion, spreading and formation of focal contacts.  Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction.  Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways.  Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling.  Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling.  Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling.  Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex.  Involved in positive regulation of mitochondrial depolarization.  Plays a role in neurite outgrowth.  May participate in the obstruction of fluid outflow in the trabecular meshwork.
What are the official names of this protein?
Myocilin, Trabecular meshwork-induced glucocorticoid response protein.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Cytoplasmic vesicle. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Secreted, extracellular exosome. Mitochondrion. Mitochondrion intermembrane space. Mitochondrion inner membrane. Mitochondrion outer membrane. Rough endoplasmic reticulum. Cell projection. Cell projection, cilium. Note=Located preferentially in the ciliary rootlet and basal body of the connecting cilium of photoreceptor cells, and in the rough endoplasmic reticulum. It is only imported to mitochondria in the trabecular meshwork. Localizes to the Golgi apparatus in Schlemm's canal endothelial cells. Appears in the extracellular space of trabecular meshwork cells by an unconventional mechanism, likely associated with exosome-like vesicles. Localizes in trabecular meshwork extracellular matrix. SUBCELLULAR LOCATION: [Myocilin, C-terminal fragment]: Secreted. SUBCELLULAR LOCATION: [Myocilin, N-terminal fragment]: Endoplasmic reticulum. Note=Remains retained in the endoplasmic reticulum.
Protein: CAN1N_EMENI
Sequence: MGDRHTIQQNLNGLLSKLNDPDPDMRYMSLNDLYGILSNPCSSYLAHDQASATRLAEGLLKALDDQHGDVQNQALKCLGPLVARLPLEGLRTLLERLSNLTTSQTIDTSVPNTALRVIVTALPRPQPNQAPSPDANMAYSAVSEVLIPRLIGPGPHKRRGSVTKGMLEKDPAKGFSSDAIDVLIQVASCFGALLQESELTALEKAVMSIIDNDTAGTVVTKRALAAISALVVYFSDEQFGILVSELVERFNSPQLSTVHRRHLIAAVGCLARTVPAKFGPHLSTLAPFIFSAVGEDNLEVSHVLHYLCTSASNVYSSRNKPKIYHQYRQLPKEKLITGM
What is the function of this protein?
Assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.  Acts as a F-box protein exchange factor when interacting with candA-C (By similarity).
What are the official names of this protein?
Cullin-associated NEDD8-dissociated protein 1, N-terminal part, Cullin-associated and neddylation-dissociated protein 1, N-terminal part.
What are the subcellular locations of this protein?
Nucleus. Note=Requires candA-C for nuclear localization.
Protein: YCX2_AUXPY
Sequence: MFILGKSNYTNFIYGHLVIRHIKYKLFDDYKKLIKKLSSKLKTSNSTKANLGDNFSLTLPTWPFFILSWFLHIRTLEFSSNGNKTANSISSVFFLFPKLLNVV
What are the official names of this protein?
Uncharacterized 11.9 kDa protein in 16S-23S DNA spacer.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLMM_GRABC
Sequence: MTQKRLFGTDGIRGTANTAPMTAEIALRVGQAAGLLFTRGDHRHRVIIGKDTRLSGYMIEPALTAGFIGAGMDVTLVGPLPTPAIAMLTRSLRADLGVMISASHNPYEDNGIKLFGPDGEKLSDATEMEIERLLHADLSGQLAAPAALGRAARLEDAAGRYIESAKSTFPKSQRLDGLKIVLDCANGAAYRVAPTVLWELGATVIPLGVSPDGFNINSGCGSTAPDYLCAQVVKHGADLGIALDGDADRLLVSDERGHLVDGDQIIALIARSWSASGRLRGDGVVATVMSNLGLERFLKANGLILDRTRVGDRYVAEQMRATGRNIGGEQSGHVILSDYATTGDGLIAALQILSVLVEEGRPASETCRVFAPLPQKLKNVRYHRDNPLLHPRVKQAIADAESGLNGHGRLLIRRSGTEPLIRVMAEAEDETTVIRIVDELCDIIAVSAESETQVHLS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: AL1B1_HUMAN
Sequence: MLRFLAPRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS
What is the function of this protein?
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde.  They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
What are the official names of this protein?
Aldehyde dehydrogenase X, mitochondrial, Aldehyde dehydrogenase 5, Aldehyde dehydrogenase family 1 member B1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SECF_MAGMM
Sequence: MQVFLKATHFDFIGRRKPAIYASLFLIGVSLVSLFTQGLNFGIDFAGGTLIQVRFEKPMDLAPVRQAIAPLDLGDTVVQSFGTPEEVLIRVEKQGADNAAQQAIVSGVLDALKPIAGEHGVEMRRVEYVGPQVGEELTEKGMLAMLYAMVAILIYISFRFELRFALGAVLALVHDVVLTMGFFSVLQKEFTLVVVAALLTVVGYSLNDTIVVYDRIREEMKRMKRQPLATIINEAVNRTLSRTLITSLTTVLVLIALFVLGGAVIHDFALTLLFGVGIGTYSSIFVASPLVLLMDPGSRRKVAAETAEETP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSPL2_SELML
Sequence: MSEHRIPVAADKQISPPISAGEQKGCKGLKRTDLMLRFAAFVCCAVTMVVLITDKQTSAIQVPGFNNLTITKTVSFDLAKAFVYLVSAAGIGAGYTLLVLVLSIISAERSKAIAWFIFVFDQLITYVLLAAAAASTEVAYMGAHAPPEASWLKVCSLFGRFCHQLGASLVTSFISTVLFAFSAAISAYYLFSNTNVRPAYSKG
What are the official names of this protein?
CASP-like protein 2U5, SmCASPL2U5.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YD007_YEAST
Sequence: MFLPIIFHTILTLLNFGKYYCLPIQEDDDKSGKEIEQILDNNIESLGLLLNSMSLSSNFTTGDPELDSLFQDDLIPELYSVLDGF
What are the official names of this protein?
Putative uncharacterized protein YDL007C-A.
Protein: UPP_WOLSU
Sequence: MAVIEVKHPLIEHKITNIRDVNTDTKSFKENLAEISSLILYEATKQLELQEVEVETPLTKTKAYRLSDSSLAVVPILRAGLGMVDGVMSLIPNARIGHIGVYRDEETLEPKHYYCKLPEDIAKRSVFLVDPMLATGGSAIYAIDYLKSQGVPKVTFLCILAAPEGIKAVTTAHPDVDIFIAKIDERLTEHGYIFPGLGDAGDRVFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: MAK_MYCUA
Sequence: MNSPATLAAKLPWSEWLPQQRWYAGRNRELAAAEPGAVVALRDDLDLVLVDVSYTDGSAERYQVLVRWDAGPVSEFSTLATIGSADDHTGFDALYDPVAPQVLLSLIDSSAVRSSSDGQVSFAREPDVELPLDAYPRVSDAEQSNTSVIFDRGQAAILKVFRRVSSGINPDIELNRVLGRAHNPHVARLLGTYEIGIPGEPPEAACPLGMATAYAANAAEGWAMATASVRDLFAEGDLYAHEVGGDFAGESRRLGEAVASVHATLAEQLGTAQATFPVDHVLARLSSTAAAVPELQQYAGTIEERFVKLVDETISVQRVHGDLHLGQVLRTPESWVLIDFEGESGQPLRERRAPDSPLRDVAGVLRSFEYAAYGPLVDHADDKQLAARAREWITRNRTAFCEGYAAASGNDPRDSELLLAAYELDKAVYEAGYESRHRPGWLPIPLRSIARLTAT
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate.  Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity).
What are the official names of this protein?
Maltokinase, MaK, Maltose-1-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
Protein: SYT13_HUMAN
Sequence: MVLSVPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQQFNVKKSTEPVQPRALLKFPDIYGPRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDSRLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
What is the function of this protein?
May be involved in transport vesicle docking to the plasma membrane.
What are the official names of this protein?
Synaptotagmin-13, Synaptotagmin XIII, SytXIII.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EDL17_ARATH
Sequence: MVMEEGRSIEEGLLQLKNKNDDSECRITACVILSTFVAVCGSFSFGVATGYTSGAETGVMKDLDLSIAQFSAFGSFATLGAAIGALFCGNLAMVIGRRGTMWVSDFLCITGWLSIAFAKEVVLLNFGRIISGIGFGLTSYVVPVYIAEITPKHVRGTFTFSNQLLQNAGLAMIYFCGNFITWRTLALLGALPCFIQVIGLFFVPESPRWLAKVGSDKELENSLFRLRGRDADISREASEIQVMTKMVENDSKSSFSDLFQRKYRYTLVVGIGLMLIQQFSGSAAVISYASTIFRKAGFSVAIGTTMLGIFVIPKAMIGLILVDKWGRRPLLMTSAFGMSMTCMLLGVAFTLQKMQLLSELTPILSFICVMMYIATYAIGLGGLPWVIMSEIFPINIKVTAGSIVTLVSFSSSSIVTYAFNFLFEWSTQGTFFIFAGIGGAALLFIWLLVPETKGLSLEEIQVSLIHQPDERNQT
What is the function of this protein?
Sugar transporter.
What are the official names of this protein?
Sugar transporter ERD6-like 17, Sugar-porter family protein 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PNRC2_DANRE
Sequence: MGGGERYNIPDRPAPKKSQPVSRGKQRSRDQNGVMHSAASGALGVPHHLRRGEKGTSYSWSPEARQAVSVDKKNGSVRFATPYDQNWESHLNKLLSAQCGQNYAGAKFSEPPSPSVLPKPPSHWVSLPMGDHRELMTFQLKSLLKVQA
What is the function of this protein?
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.  May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs.  Required for upf1/rent1 localization to the P-body.  Also acts as a nuclear receptor coactivator (By similarity).
What are the official names of this protein?
Proline-rich nuclear receptor coactivator 2.
What is the protein family that this protein belongs to?
Belongs to the PNRC family. PNRC2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, P-body.
Protein: HFLD_ACIBS
Sequence: MVELPFQQSQALNVRQNRALALAGVFQATQLTHMTAMTGQQSIGESGNFYFELLIKASLNIRPTTNNNAVQTLDFFNQLADISLGLKTLENCITQPFTNAPKSRLPKMRSAKLPMSYAMSLLQLEKKVYSNPEYVAIIEKAQQKILKQLSFFDNNYLHPSILANLAQTYVDTAGQINPRILVRGNAEAFKDTNHTNRIRACLFTGLQMAHLWRQLGGSSWNMIFSKRKLLQDIQALARLQYQVI
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCNL5_RAT
Sequence: MPVKKKRKAPGVAAAVAEDAGLKKCKISSYCRSQPPARLISGEEDFSRKKCLAWFYEYAGPDEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQSRFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPVLLDEFVEWQKIRQTS
What is the function of this protein?
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs).  May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth.
What are the official names of this protein?
DCN1-like protein 5, DCUN1 domain-containing protein 5, Defective in cullin neddylation protein 1-like protein 5, Squamous cell carcinoma-related oncogene 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Subcellular localization is independent of the interaction with cullins.
Protein: Y1812_CALS4
Sequence: MNKVKIGEKYEVDITSMGHEGEGVGRIDGIAVFVKGALKGERVIVEIEEVHKNYLKGYTVKILEKSQHRVNPLCQYADRCGGCSLQHLSYKGQLEYKTQKVKDNLERIGKIYTKVHYAIGMENPLNYRNKGQFVVGEIGREKITGFYSFHSHEIVPVDNCLIQHPLSNKVVSVVKEWLNECDISVYDRKKGKGLIRHVVAKVAFKTGEVMAIIVINGEDIPCKEELIEALKEKVPGLKSVILNINTRRTKMILGNKNIVIYGKNTIEDFIKDLRFEISPLSFFQVNPIQTEILYDKAIEYAGLTGKEVVIDVYSGIGTISLFAAKKASFVYGIESVKEAVEDAEKNAQVNGVKNVKFIWGKAEREIAKLYKEGVKAEVVIVDPPRDGCDKEVIRAIVGINPKRIVYVSCNPSTLARDLRYLEDAGYRTVEVQPVDMFPYTYHVESVALVERM
What are the official names of this protein?
Uncharacterized RNA methyltransferase TTE1812.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: PCKG_RALSO
Sequence: MNQPVMQGVPALNVPAYVKHARLVAWVSEIAALTKPERVVWCDGSQEEYDRLCAEMVAAGTLKQLNPAKRKNSYLALSDPSDVARVEDRTFICSQKQEDAGPTNNWTAPAEMRQTLNGLFDGCMRGRTLYVVPFSMGPLGSPIAHIGVELSDSPYVAVNMRIMTRMGRAVYDVLGADGEFVPCVHTVGKPLAAGEQDVPWPCNPTKYIVHFPETREIWSFGSGYGGNALLGKKCFALRIASTMGRDQGWLAEHMLILGVTSPEGKTYHVAAAFPSACGKTNFAMLIPPAGFDGWKVTTIGDDIAWIKPRQDANGQTRLYAINPEAGFFGVAPGTGEKTNFNAMATLKENVIFTNVALTDDGDVWWEGMTDTPPAHLTDWQGQDWTPAIAKETGRKAAHPNSRFTAPAAQCPSIDPEWDNPAGVAIDAFIFGGRRSTTVPLVTEARDWTEGVYMAATMGSETTAAAVGQQGVVRRDPFAMLPFCGYNMADYFAHWLKLGDQLAKSGAELPKIFCVNWFRKDEQGRFVWPGFGENMRVLKWMIDRIEGQARGDEHVFGVSPRYEELRWDGLDFSAEQFAKVISLDAQAWQQELTLHAELFAQLAHHLPQALPEAKARLEARLQG
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_BORHD
Sequence: MRKMFLAGNWKMHYTSVEAAGVAKQIVDGVQNINDDVVIMITPAFTSLCKVCEVTKGSNVLLGAQNMSYENSGARTSEISPSMLLEFGVDYVILGHSECRTYLGDTDEVINKKILAGLKHPFKYLILCIGETLSERENNKTLDVVLNQIRRGLMSVSESDLKRIILAYEPVWAIGTGKTATKEEAQEVHRAIRLEIESLYSTSAADDIIIQYGGSVNVDNVGGLMGENDIDGALIGGASLKADSFLNIVNKVAK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_TRIEI
Sequence: MKKTPRSTARELALLALSQLPKKSGSLEKKQLQEVVLAAVRTLRIEAQDILETAAAELQRGSDRLLNSQIDTTDIESARVMLYEAIELGQTAINRIGTAVELPEMLQLTNQLEVRSYAMEVLTKVNGNRKEVDKLLQESIVDWQIERLPRIDLDILRIAVAEMMFIGIQKQVAISEAVELAKRYSGEDGYKFINGVLRRVFDKINVI
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ACDD_ARCFU
Sequence: MKKFTLEEFLDLLKKYNVEEIEGVKIEGDLEIEFEGSSIDLSAIAPLYSMLSEFGNFLYHANMALGYLQRLSAALGIPTPFAAQPQLAPAAPAAPAEVPAVEELKIPAELVRAKFEPYKEEYPGKIEEVVLGATKADGGTREYTVTLGGERSLAFYTFDAPQPHLPAIAIDVFDRRPMLAKAVRMHYEDVLDNPAEWARKCVKKFGADLVTLHLISTDPLLDDTPASEAVKVLEDVLQAVKCPIIVGGSGNKEKDPEVLEKAAEVAEGERIMLASATLDMDWERIANAAKKYGHVVLSWTQMDINNQKTLNRYLLKRVEMPRDSIVMDPTTAALGYGLDYAFTNMERIRISGLKGDTDLNFPISSGTTNAWGAREAWMVDSPIEEDTPWGPRELRGPIWEIITGLTLSLAGVDLFMMMHPVAVAVLKEVFNTLGGKVSGGVADPGEWIFMEV
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).  Probably maintains the overall quaternary structure of the ACDS complex.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit delta, ACDS complex subunit delta, Corrinoid/iron-sulfur component small subunit.
What is the protein family that this protein belongs to?
Belongs to the CdhD family.