PharMolix/UniProtQA huggingface dataset:
Protein: INO1_CITPA
Sequence: MFIENFKVESPNVKYTDHEIHSVYDYETTELVHENRNGTYQWIVKPKTVKYEFKTDVHVPKLGVMLVGWGGNNGSTLTGGVIANREGICWATKDTVQQANYFGSLTQASAIRVGSYNGEEIYAPFKSILPMVNPDDIVFGGWDISDMNLADAMARARVFDIDLQKQLRPYMESMVPLPGIYDPDFIAANQGSRANNVIKGTKKEQMLQIIKDIREFKEKNKVDRVVVLWTANTERYSNVIVGLNDTVESLLASLDKNEAEISPSTLYAIACVLENIPFINGSPQNTFVPGLIDLAIRRNCLIGGDDFKSGQTKMKSVLVDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVSSNVFFMGLVNTRPRWIKYVPYVAIERAMDEYTSEIFMGGKSTIVLHNTCEDSLLAAPIILDLVLLAELSTRIQLKAEGEGKFHSFHPVATILSYLTKAPLVPPGTPVVNALSKQRAMLENILRACVGLAPENNMILEYK
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner.
What are the official names of this protein?
Inositol-3-phosphate synthase, MIP synthase, Myo-inositol 1-phosphate synthase, IPS, MI-1-P synthase.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB324_ARATH
Sequence: MMSNLPLDLVEEILSRVPATSLKRLRSTCRQWNALLKDRRFTEKHFRKAPKESLVLMLKEISVNLNVTPPSIEFKDALGLKDSHSNSEQVDIVQVLHCDGLLLCTTKDNRHVVWNPCLGETHWIQFKVDYGRVYSSFALGYIQNNESCRSYKILWRWKSNDYKSSPRQRGFEIYEFISDKWRVIDDVNHDSLVNHNYLGRCCRVSLKGNIYWLVDDVEDNSRSLLMFDFKTERFKRLCLPHFENVGHMVLSFVREEQLSVLYWSRATPKMEIWITNNIDTDATLLWRLHLDTRFNCVRIFSSLYFEEEKKVVLCCNVKLLMMIRSARTWYTLSERTMDI
What are the official names of this protein?
F-box protein At3g22700.
Protein: YRAN_ECO8A
Sequence: MATVPTRSGSPRQLTTKQTGDAWEVQARRWLEGKGLRFVAANVNERGGEIDLIMREGRTTVFVEVRYRRSVLYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: NPD4_PSESM
Sequence: MRLPAEALKDARKIVCFSGAGISAESGILTYLDQMPKLWAPYDPRALETANAFRESPALVWGWYLWRRRQVDRAQPNAAHLVWPQMVNLGYEVSVVTQNVDDLHERAGSTDVIHLHGSLTMPKCFACHRPAELTSDQMEIPDEGALVEPPRCKRCRGKLRPGVVWYGEDLPPGTWKNAVSLVKNCDALISVGTSGVVTPAADLPHIALASGATVIHVNTVDVGAQAANELMLVGRATDVLAKIHESLSTGKNNDNG
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase 4, Regulatory protein SIR2 homolog 4.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPGS2_HUMAN
Sequence: MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCVMPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLADLEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETDSFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK
What is the function of this protein?
Subunit of the tubulin polyglutamylase complex (TPGC).  The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility.
What are the official names of this protein?
Tubulin polyglutamylase complex subunit 2, PGs2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Associated with microtubules.
Protein: TRPC_BACP2
Sequence: MLNQIIARKKEHIQTLQLPDDGHFERRSFKEALVNTHRSIGLIAEVKKASPSKGIIQPNFDPLQTAKAYEKSNADCLSVLTDEPFFQGKNEYLSLIKKHIARPILRKDFIIDSIQIEESRRIGADAILLIGEVLEPQQLHELYIEAKEKGLDILVEVHAAETLEQILNLFTPEIIGVNNRNLKTFNTTVEQTKEIAPLVPKDCLLVSESGIQTFDDLTFVKKHGASAVLVGESLMREPSQEKAVQTLFGE
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: Y745_LYSSC
Sequence: MQSIVLILILQLVYVPFLTLRTIFLVKNITFLAAIFGMLEMLVYVFGLSLVFSGKQSMLAMVVYAVGFGLGIFLGAKIERKLAIGYVYTTINTQNKNEELVRFLRNEGFAVTIYVGEGRDSNRYKYEILTKRNRETELFQIVEQFEPNAFIISYEPKSFKGGFLLARMKAKQK
What are the official names of this protein?
UPF0316 protein Bsph_0745.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DMXR3_CRYX8
Sequence: MASRAKTRRSCGVGFSICKAFAEAGVARIAIVSRSPEPLEKARAELAEAWPATQILTYQGSVTDSARMTDILQQLSTVDVLVMCAAIVHNRAPATKLSTEDVQTSFDTNVLATFNLTKAYLATPMPASGSKTVINVSSAAAQVSHTRRAAYGASKAAAAQLLQCFATERDSEAVRIFSFHPGAFYTPAVAEHFSRDEIQWDDVELPAHFARWLAGPESGFLNGRYLWAHWDVDELIALKDRLAKDPAFLTIGLVL
What is the function of this protein?
Short chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the dimeric xanthones cryptosporioptides (PubMed:30996871).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase dmx-nrPKS (Probable).  The atrochrysone carboxyl ACP thioesterase dmxR1 then breaks the thioester bond and releases the atrochrysone carboxylic acid from dmx-nrPKS (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase dmxR15, and oxidized by the anthrone oxygenase dmxR16 to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by the oxidoreductase dmxR7 (Probable).  A-ring reduction by the short chain dehydrogenase dmxR18, dehydration by the scytalone dehydratase-like protein dmxR17 and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:30996871).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) dmxR6 then yields monodictylactone in equilibrium with monodictyphenone (PubMed:30996871).  In the case of the cryptosporioptides biosynthesis, monodictylactone is reduced at C-12 to an alcohol (by the short chain dehydrogenases dmxR12 or dmxR8) and hydroxylated at C-5 by dmxR9, yielding the electron-rich aromatic which could eliminate H(2)O to form the ortho-quinonemethide, followed by tautomerisation to paraquinone and complete the formal reduction to produce the 10-methylgroup (Probable).  Conjugate addition of C-4a-OH to the resulting paraquinone by the monooxygenase dmxR10 then gives cyclohexadienone, which is then reduced at C-5 by the short chain dehydrogenase dmxR3 to give the dihydroxanthone (Probable).  The 6,7-epoxide in the cryptosporioptides could be introduced by the cytochrome P450 monooxygenase dmxL3 (Probable).  The highly reducing PKS dmxL2 manufactures butyrate, which is further carboxylated by dmxL1 to form ethylmalonate (PubMed:30996871).  It is not yet clear whether the carboxylation occurs while the butyrate is attached to the ACP of dmxL2, but this unusual fungal metabolite could then be esterified to O-5 by the O-acetyltransferase dmxR13 (PubMed:30996871).  Finally, dimerization performed by dmxR5 gives the observed dimers cryptosporioptides A, B and C as the final products of the pathway (PubMed:30996871).
What are the official names of this protein?
Short chain dehydrogenase/reductase dmxR3, SDR dmxR3, Dimeric xanthone biosynthesis cluster protein R3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RS14Z_HALWD
Sequence: MSESETEQTGEHASHRTGQTHECRRCGRNQGLVGKYDIYLCRQCFREVARDMGFKKYR
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RPO12_METKA
Sequence: MYEEEKYEYICMRCGKKVRLDINEDPIRCTHCGFRLVMKPRHPVPRRYKAR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo12, DNA-directed RNA polymerase subunit P.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_CORK4
Sequence: MSAYCQVTGRKPSFGKSVSHSHRRTNRRWNPNIQRRSFYLPSEGRTITLNVSTKGLKTIDRYGIESVVAKLRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MRAY_CHLP8
Sequence: MLYYFLRYINEMFNPPGMRVIEYLTFRASAAAITALLITVFAGPSFIRFLKSHFLEPVKEEAPEEHRKKKDVPTMGGLLIILAVEISALLWAKVDDPHVWLIMLAVLWMGLIGFIDDYRKVVLKIKGGLAGKYKLVGQVALGLVVGFYTWNDPAFSVLLSKTSVPFLKNFSVDYGIFYIPVVIFIITAVSNAVNLTDGLDGLAAGNAAIVTMALGLFAYLGGNAVYAGYLSIPFISGAGEIAVVSMAIVMACVGFLWFNSNPAEVFMGDTGSLALGSAIAVIALMIKQELLLPVLAGIFFIETLSVSMQVAWFKFTKWRFKEGRRIFLMAPLHHHFQLKGWPEQKIVIRFWIISILLFLTSLMTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSPA_ECOL6
Sequence: MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKDNPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLYMHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCYLAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS
What is the function of this protein?
Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme.
What are the official names of this protein?
Stringent starvation protein A.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. HSP26 family.
Protein: SFXN1_HUMAN
Sequence: MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL
What is the function of this protein?
Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria.  Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778).  May also transport other amino acids including alanine and cysteine (PubMed:30442778).
What are the official names of this protein?
Sideroflexin-1.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
Protein: Y005_THET2
Sequence: MGALRGRWAEEEALRFLLGKGYRLLWRNRRTPFGEVDLFLEKDGVYVVVEVKQRASARFGAPLEAITPGKVRRLLQSARFLLGRDDLPVRLEAVLVHGTPKDFRLEHLVLEL
What are the official names of this protein?
UPF0102 protein TT_C0005.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: Y613_PELPD
Sequence: MFIHPEEILETLKMVNNEHLDIRTVTMGISLRGCCHPDMATFNSNVYDRILRCAEKLVRTTEEIQSLYGMPIINRRISVTPIAIVAESCQADDYCSVAETLDRAARETGIDFIGGFSALVQKGMTPGDLKLIESIPRALAITEKVCSSVNLASTKAGINMDAVALMGRIIRETARLTADRGAIGCAKLVVFANAPEDNPFMAGAFHGVGEPDCVINVGVSGPGVVNAAVRGLQGSPTLGDIAECIKKTAFKITRMGEMVGREVARRLDAQFGVLDLSLAPTPAVGDSVAAILEAMGLESCGTHGTTAALALLNDAVKKGGSMASSNVGGLSGAFIPVSEDEGMIRAVKRGSLSLDKLEAMTCVCSVGLDMVAVPGDTPAATLSAIIADEMAIGMINKKTTAVRIIPAPGTVVGDVVEFGGLLGSAPVMAVHNFSAETFIGRGGRIPAPIQALTN
What are the official names of this protein?
UPF0210 protein Ppro_0613.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: PIF1_BDEBA
Sequence: MNSESKCYRFYICFARLGSGMIAGLMPVHEIELSPEQASALDLLRSGENVFLTGGAGSGKSFLIRQFMRELDPKEMPILASTGAAAVLLGGRTFHSFFGLGIMEGGADATYERASKDKRLMSRLRKVEGVIIDEISMIPGQALMIAEALSQRARESKLPWGGMRVIAVGDFAQLPPVTHTGQRDWCFLNGVWEVSGFQTVMLSHNQRVSDNLFLDVLSDVRHGKVTERVREFLNEHVQDHDEDDPGTRLFPRKINAEKFNERKLAEIDETEVVIESIYSGSERHIETLKKASPIAEKLILKIGCQVMFLQNDPQRRWVNGTRGTVVDITADQITVRKDRGREVQVSKSSFAIQDAEGNIMAQVEQFPLTLAYATTIHKSQGATLDDLWCDLSQLWEPGQAYVALSRLRSAKGLHLIGWNPRSIIVDPKVLHFYKQFEGL
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase that efficiently unwinds G-quadruplex (G4) DNA structures.  May be involved in resolving commom issues that arise during DNA replication, recombination, and repair.
What are the official names of this protein?
ATP-dependent DNA helicase pif1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PIF1 subfamily.
Protein: FOLD_SYNS9
Sequence: MALRLDGKALAKAVESRLQAQIESNLPQAGRPPGLAVLRVGDDPASAVYVANKEKACARIGVASYGAHLPSSTPFAEVLSTIQQLNADPRVDGILLQLPLPEGLDEGPLLMAIDPEKDADGLHTLNLGRLLKGEQGPRSCTPAGVMAMLRSQGIDPAGQRAVVIGRSILVGQPMALMLQAANATVTVVHSRTKDLVAHTREADIVVVAAGRPGMVGAEHIKPGAAVVDVGIHRKPEGGLCGDVRAAEVEPIAAALSPVPGGVGPMTVTMLLVNTVVAWCRRHGVDHDLADLLS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PSSM_RHILV
Sequence: MKMFAYRGKHENFGDELNHWLWERLLPGFFDEDESQLFLGIGSILYDNFDPNMQKIVFGSGYGGYTNPPKVDGNWTFYFVRGKKTAEVLGIDPSYAIGDSGILTRSCWDAKSIEKRYPVSFMPHYESAMYGSWDKVCELAGIHYIDPRWPVEKVLTEISASHKVVSEAMHGCIISDALRVPWRAIRPIAPGNRAKWYDWASALDLEIDFDPIGPSNVVEAGASLVRNNTYLLKNITFRHRRIRQLTGNYVFGSTVKTLQRVAEKPGQLSSDESMVNAHNRMLLELDRLKQDFSKKTASVL
What is the function of this protein?
Catalyzes the pyruvylation of subterminal glucose in the exopolysaccharide (EPS) repeating unit.
What are the official names of this protein?
Exopolysaccharide glucosyl ketal-pyruvate-transferase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide pyruvyl transferase family.
Protein: SVOP_RAT
Sequence: MEEDLFQLRQLPVVKFRRTGESARSEDDAASGEHDVQIEGVRVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGRFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMSSSTLWGNISDQYGRKTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMPSLGWRWLLLLSAAPLLVFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISSRKKAVEAKCSLACEYLSKEDYMDLLWTTLSEFPGVLVTLWVIDRLGRKKTMALCFVIFSLCSLLLFICIGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRALQESSHREWGQEMVGRGTNSTGVPRSNSGSQE
What are the official names of this protein?
Synaptic vesicle 2-related protein, SV2-related protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Protein: H2AZ_ONCMY
Sequence: MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Histone H2A.Z, H2A/z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
Protein: MSCL_POLNA
Sequence: MGMMQEFKEFAIKGNVIDLAVGVIIGAAFSKIVDSVVGDLIMPVVGAVIGKLDFSNMFVVLRSVPPGIPTTLDALKKAGVPVFAYGNFITVAVNFAILAFIIFLMVKQINRLKRREVVKPTTAPAEDIMLLREIRDSLKKQA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCGL_ECO8A
Sequence: MPKPGILKSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMILPLDGRKKLVNADIEKVKLALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK
What are the official names of this protein?
Protein YcgL.
Protein: GLPB_CITK8
Sequence: MKFDTVIMGGGLAGLLCGLELQKHGLRCAIVTRGQSALHFSSGSLDLLSTLPDGQPVTNITEGLNALREQAPTHPYTTIGASAVLELAQQAQALLEASGAHLQGDVQQSHQRVTPLGTLRATWLSSPEVPVWPLAAQRICVVGISGLLDFQAHLAAASLRQHHLTVETAEIDLPELDVLRDNPTEFRAVNIARLLDNEEKWPLLHDALLPIAKTCDMIIMPACFGLADDSLWRWLNERLPCSLNLLPTLPPSVPGIRLHNRLQRQFVRQGGIWMPGDEVKKVTCRNGVVSEVWTRNHADIPLRPRFAVLASGSFFSSGLVAERDGIREPIMGLDVQQTATRAEWYQRDFFDAQPWQQFGVTTDDALRPSLAGQTVENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAARHIAERAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: GRP_HUMAN
Sequence: MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSSVSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKDVGSKGKVGRLSAPGSQREGRNPQLNQQ
What is the function of this protein?
Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
What are the official names of this protein?
Gastrin-releasing peptide, GRP.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, neuron projection. Note=In neurons of the retrotrapezoid nucleus/parafacial respiratory group, expressed on neuron projections which project into the pre-Botzinger complex.
Protein: PCP_BACAA
Sequence: MKTVLLTGFDPFGGESINPAWEVAKSLHEKTIGEYKIISKQVPTVFHKSISVLKEYIEELAPEFIICIGQAGGRPDITIERVAINIDDARIADNEGNQPVDVPVVEEGPAAYWSTLPMKAIVKKLQEEGIPASVSQTAGTFVCNHLFYGLMHELEKHDTKMKGGFIHIPFLPEQASNYPGQPSMSLSTIRKGIELAVEVTTTVEVDIVEVGGTTH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_RUEST
Sequence: MTKRTSAKYKIDRRMGENIWGRPKSPVNRREYGPGQHGQRRKGKLSDFGIQLRAKQKLKGYYGDLTEKQFRRIYGEAERVKGDTGENLIGLLERRLDAVVYRAKFVPTVFAARQFVNHGHVLVNGKRVNIPSYRVKEGDVIEVREKSKQNVAVLEAVQLAERDVPDYIEVDHSKLTATFVRAPGLADVPYPVVMEPNLVVEFYAKN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TOL4_ARATH
Sequence: MANDAAACAERATNDMLIGPDWAINIELCDLINMDPSQAKEAVKVLKKRLGSKNSKVQILALYALETLSKNCGENVYQLIIDRGLLNDMVKIVKKKPELNVREKILTLLDTWQEAFGGRGGRYPQYYNAYNDLRSAGIEFPPRTESSLSFFTPPQTQPDEDAAIQASLQGDDASSLSLEEIQSAEGSVDVLMDMLGAHDPGNPESLKEEVIVDLVEQCRTYQRRVMTLVNTTTDEELLCQGLALNDNLQHVLQRHDDIANVGSVPSNGRNTRAPPPVQIVDINHDDEDDESDDEFARLAHRSSTPTRRPVHGSDSGMVDILSGDVYKPQGNSSSQGVKKPPPPPPHTSSSSSSPVFDDASPQQSKSSEVIRNLPPPPSRHNQRQQFFEHHHSSSGSDSSYEGQTRNLSLTSSEPQKEEKPEDLLFKDLVEFAKTRSSKANNNNRSL
What is the function of this protein?
Might contribute to the loading of the ESCRT machinery.
What are the official names of this protein?
TOM1-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the TOM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: TYRP1_AMBME
Sequence: MLGPATFLPLTAALLLLIPGGRAQFPRQCVTPEALRSGQCCPGLFPALTPDPADRCGASVGRGRCAPLQVDARPHGPQYPHDGVDDREQWPTRFFNNSCLCAENFSGYDCGSCKPGWVGVNCNQRVLAVRRNILDLTAQERRRFIAALDLAKRTTHPHYVIASRRYAEIMGPDGNSTQFENVSIYNFFVWTHYYSIGKTFLGAGRESFGGIDFSHEGPAFVTWHRYHLLQLERDMQEMLQDPTFALPYWNFAIGGNECDICTDDFMGARSNFDSILLSSNSVFSQWRVLCESLEGYDTLGTICNSTEGGPIRRNPGGNVARPMVQRLPEPQDVALCLEVGLFDTPPFYSNSSESFRNTVEGYSEPSGKYDPSVRSLHNLAHLFLNGTGGQTHVSPNDPIFVLLHTFTDAVFDEWLRRHNADISLYPLENAPIGHNRQYNMVPFWPPVSNNEMFVTAPESLGYSYEVQWPSRALNFTEIITIAVVAALVLVAVIFAAASCAVHRSRKDDVHQPLLGEQYPRYSEEYERDASQSAV
What is the function of this protein?
Plays a role in melanin biosynthesis.  Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid.  May regulate or influence the type of melanin synthesized.  Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.
What are the official names of this protein?
5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, Tyrosinase-related protein 1, TRP-1, TRP1.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Protein: HSCB_BUCAT
Sequence: MNYFTLFDLPRKFNIDKKLLSQNFYKLQLKFHPDLFINDSESKKKIILEKSIQINKGYKTLKNFLNRAIYFLCLNGYEVKKETLLLKNNDFLIRYFSLYEQLDNLKENNFNKKELNNLEQIIQKKIIYCKKKIELEFEKTRYKKVIKIISELLFFEKIKDVLKKEYNIYLRQIN
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: LEU1_STAAE
Sequence: MSSHIQIFDTTLRDGEQTPGVNFTFDERLRIALQLEKWGVDVIEAGFPASSTGSFKSVQAIAQTLTTTAVCGLARCKKSDIDAVYEATKDAAKPVVHVFIATSPIHLEHKLKMSQEDVLASIKEHVTYAKQLFDVVQFSPEDATRTELPFLVKCVQTAVDAGATVINIPDTVGYSYHDEYAHIFKTLTESVTSSNEIIYSAHCHDDLGMAVSNSLAAIEGGARRIEGTVNGIGERAGNAALEEVALALYVRNDHYGAQTALNLEETKKTSDLISRYAGIRVPRNKAIVGQNAFSHESGIHQDGVLKHRETYEIMTPQLVGVSTTELPLGKLSGKHAFSEKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAEVHVNLLIEGKTVNGFGIDHDILQASCKAYVEAHAKFAAENVEKVGN
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.