PharMolix/UniProtQA huggingface dataset:
Protein: SRB8_ASPTN
Sequence: MIPHSSAGVQQWGHHPLHALNPGAGRTDTASALGPSDLQLEKAPMSAPQPQLRQPAVVDLTTHSGDTSEREPPSKRLRLDLPSVASTGDASPASGNGEPRNTPSTSTPTAKPSSLSWRGRPVWSFQALISEIPGSGGMSEEDAAAVAQSGKPASPPPFPVLPWKYAPPEAAGNKSVKSRDSSPAKKVQTTPYHIECPSVAPVLKGQKVADFSPWTGNHPEDVLNEQTAKQGHYDRTQVSQNESNTARPSLYAQLKHRSGLQMLSSVFAAALEKRQSHNLVNAPSTFKPPPRVTLTDNKREAWLRDLANPSVPLRRLSRTIPHGIRGKALLDQCLSKWIPVNRAVWLAKCVGANEIRAFKRKGTSGAVVIGLEAKWVREWTAHVQQFLEGLVAACGTADWKMKMTYAVGLTARLFFERLLDDEQYLGWFLSSLEAASLNTVPVWLLMLGIYWDSIMRYRKRGRRLAEALLEKLRQVTNPEHATTLRPLVDRLSLHIRTLVVEHTSSVILPNSWAKYKDLVLSCLNMKDNTHKAIFQNVAERNARIQLSKDRQDSGQRSPQQRVIHLFDAVCSTHDVASAAAACLKTIDDKSLLVTKLLEWTATPFRCGLCRVYTAVRLLRKWKMSGVDIDTYILSFLTRTGNRASLTMDNIYHVISELVRSQTFSVGRYLQWLMAKGVSSSNQSDHSIDLYLLKQLPMTRLPDHVRNLRNTLLYRAGVPATLEDSTIAELKASIAGRLPNIFGNEVEHTMVVESPSLDLTWAVKSEIGQWLRRGISGHCRNATSAMAGITVPADRNVSRLTPDEFYHIRDVLESFGDLSMLADVVKQTTSCDDNIVLASAADTVNYHFDSFCVIGATSDLFRSLVESYARLKRLGTPNLDLVFSLIELGLRLPQECNTVALLRQDLLRIESKSALAAPSPLSDNPSTAINEADPSFRSKLDQLLSSGGGMDESTMASIFASLTNILTGRNEDVKLSANETCRYLAYLRPFHPKHFDAMLVRWVCGLLKSSARSTMPHILPPLIGVGCVTIHAFVFLVKKLLQSERIASKIPNPARLKMDILDLLVPPAPGQSRYFDLVTYRFHLAQQEFLLKYYKETLDIICDALSTNAAAAGINSELRSSATTLLRLLLAQEPEDVVQYCLQKISAQHSTFTSVLQDTLDQLLQSVSLHDPQVSMAENVIRTTDDFSLPFCQLKLQVLSNAESKENMGDGIVDVMFKAAVADTRAKGSNWIGLVRLMSPNSVQQIRERAEKEFFAVPLFAETLGDQSLSYAPNTEALETAKLYLTIIDKLAYSIPEAGVQSVGPILVEKMDLLLHKLVVMQTSLVTRQGVVSDQATQSRANFERALAFWFSALLRMIVIHRTAFNVPSSVPRATVVQDQSRLLVSIFCISLARLPTNILRLYPTADYFPHPISSEGYRPCPGILLQTHALDVAASLIDTFPDESRQQCARFLKDKCPPFLQFQNDNRFSYLLGPVPDAGTSNIPPPASVPSPAAAAASTPTPTPSSGLPPGSSTQQASSTLSGIPTGVSEDCVASRLRLQYRGRTIGPYPVRPWELLEDAAPIVGVNDTAVNLKFFDARRVRA
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YAJ9_YEAST
Sequence: MNKYLFDHKIWSTPYYFYCEEDCHRLFLSFIEGRTFEKPTSNAEENVQETEAGESFTLNPGEDFQNCFPRQRIL
What are the official names of this protein?
DUP240 protein YAR029W.
What is the protein family that this protein belongs to?
Belongs to the DUP/COS family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Punctate pattern.
Protein: RPR1A_PONAB
Sequence: MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAGDIYSED
What is the function of this protein?
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2.  May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
What are the official names of this protein?
Regulation of nuclear pre-mRNA domain-containing protein 1A, Cyclin-dependent kinase inhibitor 2B-related protein, p15INK4B-related protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0400 (RTT103) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS9_METKA
Sequence: MGRVVQTTGKRKTAIARAVIREGEGRVRVNKRPVNIIEPEMARMKIMEPLIIAGEDIVSQVDIDVKVQGGGWMSQAEAARIAIARGLVEWTGDPDLRDAYMAYDRHMLKGDPRRKEPKKFGGRGARARRQKSYR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS18_RHOPB
Sequence: MAEAGARRPFFRRRKTCPFTGPNAPKIDYKDSKLLMRYVSERGKIVPSRITAVSAKKQRELARAIKRSRFLGLLPYVIR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y4575_TERTT
Sequence: MLIVISPAKNLDYDSPVPTAKSTKAALLDDASELMDGLKTLAPQDVSQLMGISDKLGLLNYDRFQDWQLPLTKKNARQALLAFKGDVYVGLDAYNFSAEDFDFAQQHLRILSGLYGVLKPLDLVAPYRLEMGTRFANDRGKDLYAFWGDKVTAELNKPIKKLASNTLINLASNEYFKSVKPAHLQAQIITPVFKDWKNGTYKIISFFAKKARGRMSAYIIKNQITDPELIKQFDWDGYQYNSAMSDAGQWVFTRKQ
What are the official names of this protein?
UPF0246 protein TERTU_4575.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RR15_AETCO
Sequence: MIKNSFISLQEKKDESRGSVEFQVFSFTNKIRRLTSHLELHRKDYLSQRGLRKILGKRQRLLVYLSKKNRVRYKELIHKLNIRQLKTR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARSC_BACHK
Sequence: MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVVTLCSHADSVCPSTPPHVNRVHWGFDDPAGKEWSEFQRVRDEIGERIKCFSETGE
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_ECO55
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RBL_GEUQU
Sequence: VGFKAGVKEYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEESQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALFKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREAAKWSPELAAACEVWKEIKFEF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PCMD1_HUMAN
Sequence: MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK
What is the function of this protein?
Substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:35486881).  Specifically binds to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but does not display methyltransferase activity (PubMed:35486881).  May provide an alternate maintenance pathway for modified proteins by acting as a damage-specific E3 ubiquitin ligase adaptor protein (PubMed:35486881).
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor.
Protein: NS1BP_MOUSE
Sequence: MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHGVSHVKLDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNPLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISGSSTGCLSSPNASMQSPKHEWKIVASEKTSNNTYLCLAVLDSTFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQPDELLEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNIDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKSWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLDGKLFVGGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGITTVGNTIYAVGGFDGNEFLNTVEVYNPQSNEWSPYTKIFQF
What is the function of this protein?
May play a role in cell cycle progression in the nucleus.
What are the official names of this protein?
Influenza virus NS1A-binding protein homolog, NS1-BP, NS1-binding protein homolog, Kelch family protein Nd1-L, ND1-L2, Nd1-S.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with actin filaments. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Note=Not associated with actin filaments (PubMed:15684717).
Protein: TBH1_CAEBR
Sequence: MKCANAAALLFFVLCDIGVHGGEIVAELLHSNVTVKWQTDYERQTVDFSIWFGAKTPDLLFLGFSDFGDMNSSDVLMYDNVKREIMDSYTNRDYKIIPDLSQDFQQLRRRKDHFVVRRKLTTCDSRDYAFQRGTTQFYIAASFGYRNLVDIRDKKWILDKKFGKVIEGPTDQPSTDEGVSSLERDVQLVIVNSNSPDPVPNVETTYECIIRKMPFDTVHKTYHIVRMEPYITPGNEHLVHHMEVFLCRDEVEEWSGNCNDPKKPKKSKSCSHVIAAWAMGEGPIHYPREAGLPIGGKGKNEYVMVEIHYNNPELHKGVMDTSGFQFYVTGLLRIYDAGIMELGLIYSDANSVPPNQKAWAMNGYCPSQCTQNLPEEGINIFASQMHAHLTGRKLWTSQYRDGVQIGDVNRDEHYSPHWQHLQQLRPMVRVMPGDTLVTTCVYDTRRRSNVTFGGYGITDEMCVNYIYYYPASEVEVCKSAISNSTLRAYFSQRHGMDGKTMKISDMYNGVKDWSNGVDEEFYNVLNVGNVNMNCLKSNGESFEFKSKDPRQGWENMARPRLFSGSFIRTRDRFQCPAINDMINFE
What is the function of this protein?
Converts tyramine into octopamine, a neurotransmitter involved in pharyngeal pumping and egg laying.
What are the official names of this protein?
Tyramine beta-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
Protein: CAX6_ARATH
Sequence: MYMELYLMFSNFFKSIRWCKVPAFMQAKVEMGLVNEVELKSLLEQETDSPQTNAASLMEQGSLRERRAKAPRNSVVQSFKIVILSNKLNLLLPFGPLAILVHYLTDNKGWFFLLSLVGITPLAERLGYATEQLSCYTGATVGGLLNATFGNVIELIISIIALKNGMIRVVQLTLLGSILSNILLVLGCAFFCGGLVFPGKDQVFDKRNAVVSSGMLLMAVMGLLFPTFLHYTHSEVHAGSSELALSRFISCIMLVAYAAYLFFQLKSQPSFYTEKTNQNEETSNDDEDPEISKWEAIIWLSIFTAWVSLLSGYLVDAIEGTSVSWKIPISFISVILLPIVGNAAEHAGAIMFAMKDKLDLSLGVAIGSSIQISMFAVPFCVVIGWMMGAQMDLNLQLFETATLLITVIVVAFFLQLEGTSNYFKRLMLILCYLIVAASFFVHEDPHQG
What is the function of this protein?
Vacuolar cation/proton exchanger (CAX).  Translocates Ca(2+) and other metal ions into vacuoles using the proton gradient formed by H(+)-ATPase and H(+)-pyrophosphatase (By similarity).
What are the official names of this protein?
Putative vacuolar cation/proton exchanger 6, Ca(2+)/H(+) antiporter CAX6, Ca(2+)/H(+) exchanger 6, Protein CATION EXCHANGER 6.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: RRF_EHRCJ
Sequence: MINEMKQDAKNRMEKTLSVYLSDIDGIRTGRARTSVLDGIVVETYGGRVKLNTISSISVSDNKTLMIKVWDSNNIGAIKTAIMNSNLGFGFSCEATTIRLTVPEMTQDMRKNLVKLLGKISEDCRVSVRNIRRDIMDKLKVMQDNKEISEDDLRVSGTEIQKITDDVMKKINDAFSSKEKELLQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_SPIOL
Sequence: MATSYGFFSPSVPSSLNNKISPSLGINGSGFCSHLGISKRVFCSSIEASEKHAAAGVSSSESRVSRLVNRGCKLVGCGSAVPKLQISNDDLSKFVETSDEWIATRTGIRQRHVLSGKDSLVDLAAEAARNALQMANVNPDDIDLILMCTSTPEDLFGSAPQVQRALGCSRTPLSYDITAACSGFMLGLVSAACHVRGGGFKNVLVIGADALSRFVDWTDRGTCILFGDAAGAVVVQACDSEEDGMFAFDLHSDGGGGRHLNASLLNDETDAAIGNNGAVTGFPPKRPSYSCINMNGKEVFRFAVRCVPQSIEAALQKAGLTSSNIDWLLLHQANQRIIDAVATRLEVPSERVLSNLANYGNTSAASIPLALDEAVRSGKVKPGNIIATSGFGAGLTWGSSIIRWG
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  KAS III catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities (By similarity).
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, chloroplastic, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NPT2C_MOUSE
Sequence: MPNSLAGGQVPNPTLDAFDLVDRSLRNAGISGSIPGLEEGGTDPWTFSPLKNADQLKEVGMASRLRRVVSSFLKACGLLGSLYFFICSLDILSSAFQLLGSKMAGDIFKDNVVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVASKLLTVQVSVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLESATAALERLSELALGAASLQPGQQAPDILKALTRPFTHLIIQLDSSVITSGITSNTTNSSLIKHWCGFRGETPQGSSEGCGLFSSCTERNSSASPEEDRLLCHHLFAGSKLTDLAVGFILLAGSLLVLCVCLVLIVKLLNSVLKGRIAQAVKTVINADFPFPFGWLSGYLAILVGAGLTFLLQSSSVFTAAIVPLMGVGVIDLERAYPLFLGSNIGTTTTALLAALASPADMLIFAVQVALIHFFFNLAGILLWYLVPVLRLPIPLAKRFGNLTAQYRWVAIVYLLLTFLLLPLAAFGLSLAGGTVLAAVGGPLVGLVLLIILVNVLQQHRPSWLPRCLQSWAWLPLWLHSLEPWDRLVTACCPCRACSNSPMTSKVAHCYENPQVIASQQL
What is the function of this protein?
Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (PubMed:12690469, PubMed:16113079).  The cotransport has a Na(+):Pi stoichiometry of 2:1 and is electroneutral (PubMed:16113079).
What are the official names of this protein?
Sodium-dependent phosphate transport protein 2C, Sodium-phosphate transport protein 2C, Na(+)-dependent phosphate cotransporter 2C, Sodium/phosphate cotransporter 2C, Na(+)/Pi cotransporter 2C, NaPi-2c, Solute carrier family 34 member 3.
What is the protein family that this protein belongs to?
Belongs to the SLC34A transporter family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membrane in the kidney.
Protein: GALT1_RAT
Sequence: MRKFAYCKVVLATSLVWVLLDMFLLLYFSECNKCEEKKERGLPAGDVLELVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIAFNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRSQQWLLRNVTLPEIF
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:12199709, PubMed:12364335, PubMed:12419318).  Has a broad spectrum of substrates such as apomucin-, MUC5AC-, MUC1- and MUC2-derived peptides (By similarity).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 1, Polypeptide GalNAc transferase 1, GalNAc-T1, pp-GaNTase 1, Protein-UDP acetylgalactosaminyltransferase 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
[Polypeptide N-acetylgalactosaminyltransferase 1]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Polypeptide N-acetylgalactosaminyltransferase 1 soluble form]: Secreted.
Protein: SECA_ARTS2
Sequence: MASLIEKLLRTGDKKTLRQLRNYADSINALESSFQTFTDAELREETDRLRERHQDGEKLDDLLPEAFAAVREASSRTLGMRHFDVQLMGGAALHLGNIAEMKTGEGKTLVATAPAYLNALTGNGVHVITVNDYLAEYQSDLMGRVYRFLGLTSGCILSNQDPAVRREQYAADITYGTNNEFGFDYLRDNMAWDKSELVQRGHHFAIVDEVDSILIDEARTPLIISGPAQGDTNRWYSEFAKVVTRLKPDEDYEVDEKKRTVGVLEGGIEKVEDYLGIHNLYESANTPLIGFLNNAIKAKELFKRDKDYVILDGEVLIVDEHTGRILAGRRYNEGMHQAIEAKEGVEIKAENQTLATVTLQNYFRMYNKLSGMTGTAETEAAEFMSTYKLGVVAIPTNRDMQRIDQPDLVYKNEAVKFDAVVKDIAERHEKGQPVLVGTTSVEKSEYLSRLLAKEGIRHEVLNAKNHAREAAIVAQAGRKGAVTVATNMAGRGTDIMLGGNAEFTAVAELAAKGLDPEENSEEYEAAWPAAFEAAKQAVKDEHEEVLELGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLTDDLMRLFNSGAAERLMNSSVPDDVALESKLVSRAIASAQGQVEGRNAEQRKNVLKYDDVLNRQREAIYGDRRRILEGDDLHEKVQFFLEDTITALIDAATSEGTGDDWDFNQLWTNLKTLYPVSVTSHDVIDEAGGKSRITVDFLKEEILSDARLVYQAREQAIGSESMRELERRVVLSVIGRKWQEHLYEMDYLKEGIGLRAMAQRDPLVEYQREGFIMFQAMMEAIREESVGFLFNLEVEVTPAEDVVVADGAGEHTEHHEPQIHAAGLEAPEKPAQLQYTAPGEDGASQTRVEGRSSGRSGNPAKAAQDGARKPAPKKKKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RS20_METS4
Sequence: MANTVSAKKMTRKIAKRTAINRSRRSRMRTFIRKVEEAIASGDAATALTALRSAEPEIMRASQKGIVHKNTASRKVSRLTARVNALQA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: CAV1_CANLF
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMAEEMSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPFFEAVGKIFSNIRINMQKET
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1, Vesicular integral-membrane protein VIP21.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Golgi apparatus, trans-Golgi network. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
Protein: RBS2_HYDCU
Sequence: MSISQIDDYRTQYTLETFSFLPELTADEIYDQIVYIINQGWSPALEHEEPAKASDHYWGMWKLPMFGTRDPNEVLAEIDACRQAYPNHLIRLVGYDNYTQCQGHNFVVYRPRGM
What is the function of this protein?
Replacing the endogenous type I ccbLS genes in H. neapolitanus with this carboxysomally targeted enzyme reconstitutes RuBisCO with about 25% of normal activity; the active enzyme is targeted to carboxysomes (PubMed:18974784).
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit 2, RuBisCO small subunit 2, Carboxysomal form I RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: GATA_BACCQ
Sequence: MSLFDHSVSELHKKLNNKEISVTDLVEESYKRIADVEDNVKAFLTLDEENARAKAKELDAKIGAEDNGLLFGMPIGVKDNIVTNGLRTTCASKMLANFDPIYDATVVQKLKAADTITIGKLNMDEFAMGSSNENSGFYATKNPWNLDYVPGGSSGGSAAAVAAGEVLFSLGSDTGGSIRQPAAYCGVVGLKPTYGRVSRYGLVAFASSLDQIGPITRTVEDNAYLLQAISGLDRMDATSANVEVGNYLAGLTGDVKGLRIAVPKEYLGEGVGEEARESVLAALKVLEGMGATWEEVSLPHSKYALATYYLLSSSEASANLSRFDGVRYGVRSDNVNNLLDLYKNTRSEGFGDEVKRRIMLGTFALSSGYYDAYYKKAQQVRTLIKNDFENVFANYDVIIGPTTPTPAFKVGEKVDDPMTMYANDILTIPVNLAGVPAISVPCGFGANNMPLGLQIIGKHFDEATIYRVAHAFEQATDYHTKKASL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PMP37_PIG
Sequence: METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTWRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEIQSVGLLSRLRDFLSDRGRRLGEKIERIGQKIKDLSEFFQS
What is the function of this protein?
Exerts antimicrobial activity against both Gram-positive and negative bacteria with minimal inhibitory concentrations ranging over 1-4 micro molar.  Its activity appears to be mediated by its ability to damage bacterial membranes.
What are the official names of this protein?
Antibacterial peptide PMAP-37, Myeloid antibacterial peptide 37.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.