PharMolix/UniProtQA huggingface dataset:
Protein: YBEY_SALAR
Sequence: MSQVILDLQLACENHSGLPDEAQFQRWLDGVIPQFQEASEVTIRLVDEAESHDLNLTYRGKDKPTNVLSFPFEAPPGIEMPLLGDLIICRQVVEQEAQEQDKPLEAHWAHMVVHGSLHLLGYDHIDDDEAEEMESLETEIMLAMGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3725_ARATH
Sequence: MSVTTSFGIWLNHINLDNQASFLYNNPHFCNRRFNRISMLRTVSLARNRLRSETPSSFLARDRLRSKTPSSSPFSSKRHTPKTSEIEEESTPKDSVLLNPKDPSSAPKLFLVQPRLAPPKYLQAKLNEALCLANSLEEQRYGYFESDFFDKELPSHVVVQNPVRRSSKPRVDTYFGSGTVDNIKCHLNAEDSKEEVDAVFVNAILTAIQQRNLERIWAKPVLDRVGLIIEIFNAHAHTKEAKLQAELAALMYNKSRLVRVRGTDGRHTFGQFGEAEVVSARGRAGSKGTGGGFVGGAGETELQLQRRRISDRRIRLLSQIKEAQRTRLLQRAGRKKRVGLEGESSGTIAVVGYTNAGKSTLISALTKTALYCNERLFATLDPTLKSAHLPSGNFVLLSDTVGFISDLPIQLVKAFQSTLEEVVEADLLLHVVDSTAPNIEEHRSTVLHVLNQIGVPEEKLQNMIEVWNKIDYEEDEVEEEKYLDDGEGVGEEDEDEADLKAEETVDASEATVDEDQIQNGDGDDADGWLLSEDENADDPEFWKVPEVAKVDAANKKGPDVRVSALTGVGLKELLYLIDDKMKEKKLKSPTIVERSELHKRKWRPPRNDDEEERLIPLDQR
What are the official names of this protein?
GTP-binding protein At3g49725, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: STPG2_HUMAN
Sequence: MYDRAPRLLKLAEGGSTEAHVGPGSYQVPFLKQQATGSNAPFLSLTARESTFTIASSIEKAVPGPGHYNVSEAQKISRSPTLTRSVDVPSIPSCGKSYGYHINDDGSIIKCFPPACDSTLGPAYYKPQFDVSNATLKYKGIHFGNSSGRQELPKKSGPGPGQYDIVQKKTSYYENVNIKRDQQQNYCSFIPRLYEIIVLQEKKKRFLPMKSITPAPGTYNEPRTALKSLKKTSGLKNIPFGQSAVRFTQDIRTEEMPGPGFYNVLNNTIIASVRNICSKKQKKSAFGSSVPRTFFSVQKEACATPGPADYQEFWHSQGVGISDELPNLTNKYAAFLSRAKRTMKVPDMVIPAPGSYDVHKSYEMSQVKHKYMPPRSLVAKRKHASFLSATPRCLEKVTDGPGPAAYNPVLRKSCPIPLFVKASKRFEESKEITPGPATYEISQEKKKGNLIGEMAADIM
What are the official names of this protein?
Sperm-tail PG-rich repeat-containing protein 2.
Protein: PFKA_AQUAE
Sequence: MRIGILTAGGDAPGMNAVIRAVVRSAEREGHEVIGIKRGYKGLIEGDFIKLTSRDVGGILDRGGTILLSSRDPRYKKLEYREKAYKNLNEQGIEALIILGGEGTLAGAKLTAEETGIPVIGVPCTIDNDVGGTEYCIGYDTALRNAVDAIDKIRDTASSHERIFIVEVMGRNRGFIAVEAGLATGAELILIPEERFPREQIPEEIEKAKKLGKLHFIIVLAEGYCRAKELEDFLLEKIGDKYGEIRSTVLGHIQRGGIPTHFDRIMGTKFGVVAYESLIAGERSGFVAYEKGKFYIEDFEKAQEYKPIDREAYKLNTRLAI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_BURCJ
Sequence: MELNNLKPAAGAKHAKRRVGRGIGSGLGKTAGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKRGFTSLTKEFVGEVRLGDLEKLPVDEIDLLALKQAGLVGELTKSAKIIATGELKRKIVVKGLGATKGARAAIEAAGGSFAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RNH2_ACICJ
Sequence: MPDFSRELALGGVVAGVDEVGRGPLAGPVVAAAAILPADLPPEIAALIDDSKRLSPAQREAALAALIESGAAISAAAASVAEIARLNILQASLLAMRRAVARLAVRPDHVLVDGQVAPDLPMPCTPVVGGDGLSLSIAAASIAAKLVRDRAMSRLDRRYPGYGWARNSGYGTKTHRDAILGLGITPHHRRGFGPLLPPA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_ECO24
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RLMH_METTP
Sequence: MHMRIIAVGRIRERFWQDAASYYLRRLSPYTRLDVVEVREEDPIKEGRGILAHLCGGVTVALDEHGESMSSQELALWLQNRIVEGCGSINWIIGGPEGLSQDVLNRSDLQLSLSKMTFPYQMARILLLEQLYRAFKIIKNEPYHR
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Putative ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTOX_ECOSM
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQMLWDELSRHNEDDPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEQLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTEIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPAHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: Y038_MYCBO
Sequence: MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVVTMNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGSAVYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAAAATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTIVGRRGQPVIGR
What are the official names of this protein?
Uncharacterized MFS-type transporter Mb0038c.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Drug:H(+) antiporter-3 (DHA3) (TC 2.A.1.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAPA_STUST
Sequence: MSLTRRQFAKANAAAIAATVAGMPIASTASNLVTEADATNLKWDKAPCRFCGTGCGVMVATRENRVVATHGDVKADVNRGINCVKGYFLSKIMYGTDRLTQPLLRMKDGKFDKQGEFQPVTWDQAFDIMEEKYKAALKAGGPEAIGMFGSGQWTIWEGYAANKLMKAGFRSNNIDPNARHCMASAAFGFMRTFGMDEPMGCYEDIEAADAFVLWGSNMAEMHPVLWTRLTDRRLSAPHVKVAVMSTFEHRSFELADIPMIFNPQTDLVILNYIANHIIQSGAVNKEFIDKHTRFAKGATNIGYGLRPTDPLELKAENAAVANTWTDIGYEDYVEFLKPYTLEHAAKESGVPAERLKALAELYADPKVKVMSFWTMGFNQHTRGVWANNMIYNIHLLTGKISEPGNSPFSLTGQPSACGTAREVGTFSHRLPADMAVTNPKHRAITEKIWKLPEGTIQEKPGFHAVDQSRKLKDGVLKVYWTQVTNNMQAGPNVMQEILPGWRNPETFVIVSDVYPTVSAQAADLILPSAMWVEKEGAYGNAERRTQFWHQLVTAPGEARSDLWQLVEFSKRFRVDEVWPAELLSKAPEFKDKTLFDVLFKNGQVDRFSNDEIAEGYANYEAEAFGFYLQKGLFEEYAEFGRGHAHDLAAFDVYHRERGLRWPVVDEKETQWRYREGYDPYVEAGSGVQFYGNADKKAIIFALPYEVPAEVPDEEYPFWLSTGRVLEHWHTGSMTQRVDELHKAVPDALVYMHPEDARKLNVRRGSVVKIVSRRGEMQGRVETRGRNKPPMGLVYVPFFDANKLINKVTLDATDPISKQTDFKKCAVKIEVVSIA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
Protein: SPAG1_MOUSE
Sequence: MTAKAKDCPSLWGFGTTKTFKIPIEHLDFKYIENCSDVKHLEKILYVLRSGEEGYYPELTEFCEKCLTNLAPKSRALRKDKPAETASSFSAEEWEKIDSDLKSWVSEIKREENTCHFHDPENHPGVEDPLPPVRGSTCCPHSGKETYSKSKTAKKRIPRDYAEWDKFDVEKECSKIDEDYKEKTVINNKAHLSKIETKIETAGLTEKEKSFLANREKGKGNEAFYSGDYEEAVMYYTRSLSALPTAIAYNNRAQAEIKLQRWSSALEDCEKALELDPGNVKALLRRATTYKHQNKLQEAVDDLRKVLQVEPDNDLAKKTLSEVERDLKNSEPVSELQTKGKRMVIEEVENSGDEGGKGSADEREDGGSDEAAMGNIQKKLMVRRSEGGRRSRRGRTPGPRAEQQGGLRETATASTGDSHYPEEPRAADNPSGLKRRGNELFRGGQFAEAAAQYSVAIAQLEPTGSANADELSILYSNRAACYLKEGNCRDCIQDCNRALELHPFSVKPLLRRAMAYETLEQYRNAYVDYKTVLQIDCGIQLASDSANRIARILTELDGSKWRERLPPIPAVPTSEPLRVWLPAAETPDQDPCPNNCMPSITDEKMFQALKEEGNQLVKDKNYKDAISKYNECLKINSKACAIYTNRALCYLKLGQFEEAKLDCEQALQIDGENVKASHRLALAQKGLENCRESGVDPSQVLLSPDSSEAARHLDTKNDTAPPSKGRERRRIQVQEVDGSSDEEPERPAEASATSAPARDGVEDGGSAEPAEKLDVSKPTNAYEFGQVLSTISARKDEEACAHLLAITAPKDLPLLLSNKLEGDTFLLLIQSLKSHLVAKDPSLVYEHLLYLSKAERFKTMLTLINKGQKEQMAQLFDGLSDTQSDGLTAEDVQALRRQYEL
What is the function of this protein?
May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity).  May play a role in fertilization.  Binds GTP and has GTPase activity (By similarity).
What are the official names of this protein?
Sperm-associated antigen 1, Infertility-related sperm protein Spag-1, TPR-containing protein involved in spermatogenesis, TPIS.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle. Note=Colocalizes with tubulin.
Protein: NKAP_HUMAN
Sequence: MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK
What is the function of this protein?
Acts as a transcriptional repressor (PubMed:14550261, PubMed:19409814, PubMed:31587868).  Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development (PubMed:19409814).  Also involved in the TNF and IL-1 induced NF-kappa-B activation.  Associates with chromatin at the Notch-regulated SKP2 promoter.
What are the official names of this protein?
NF-kappa-B-activating protein.
What is the protein family that this protein belongs to?
Belongs to the NKAP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBSA_OCEIH
Sequence: MKIVMENIHKSFGSNNVLEGVDFSLEPGEIHALMGENGAGKSTLMNILTGLFPSNQGSITIDGVKTQYKDSKESEQAGIAFIRQELNILPQMTVLENLFIGKEMTNSFGFLREKVMKEKAEEVFSRLDFSIPFDKEAGECSVGEQQLIEIAKALMLDAKIIIMDEPTAALTDREIDKLFEIMKELTQQGVALVYISHRMEEIFAICDRITVMRDGISVKTSWIKDTNYNEIVKQMVGRELDERYPERTPTFGKPVLQVNNFSRKGYFNDIKFSVREGEILGVSGLMGAGRTEIMRAIFGIDEVDQGEILLDGKKLTIKDPTDAMKAGLAFITENRKDEGLVLDFSIRENIGLSNLNSFSNKGFIKGKDEKDFVELMIKRLQIKTQTQELPVGNLSGGNQQKVVIAKWVGTSPRVLIMDEPTRGIDVGAKREIYQLMNELTERGLAIIMISSDLPEVLGMSDRIMVIHEGEISGELVREEATQEKIMTYATGGNGHE
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KHSE_RHOE4
Sequence: MTITLPIGLSVTARVPASSANLGPGFDTLGLALGLYDEIVVTTTDSGLQIRVEGEGAADVPWGPSHLVVRAIERGLEAAGVWASGLDVLCRNAIPHSRGLGSSASAAVGGLAAANGLARALDAEIGLTEEQLVQLSSEFEGHPDNASASVLGGAVVSWSCPPAVEGDEPIYSAAKLDVHPDIRAVALVPEERSSTAHTRGLLPELVPHQDASFNASRSALAVVALTARPDLLMAATEDRLHQAQRAPALPLTTRWIGILREAGIAATVSGAGPTVLALSTEPFPVELAEAARADGLRVLELDIADGVEVSTTTV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_STRPN
Sequence: MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQMLESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: Y248_TREPA
Sequence: MWHLRCSNWRGSGVFGMCFSLSGCVMGQWCVSRAIVRGHTQGGAVREVVRELLLGPQHHGYARLVDPAVRPLSCFSRGDTLYIDLPVGVLSPKYRTCSLHRAYELXERSVVLNCAPVKRVCFYVGGRAGFESDG
What are the official names of this protein?
Uncharacterized lipoprotein TP_0248.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ADA1D_HUMAN
Sequence: MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEMQAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVEAVSLGVPHEVAEGATCQAYELADYSNLRETDI
What is the function of this protein?
This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
What are the official names of this protein?
Alpha-1D adrenergic receptor, Alpha-1A adrenergic receptor, Alpha-1D adrenoreceptor, Alpha-1D adrenoceptor, Alpha-adrenergic receptor 1a.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OBG_FRAP2
Sequence: MRFVDEVVIKLQAGKGGNGCVSFRREKYVPRGGPDGGDGGHGGSIYLKADENVNTLIDYRYKREYYAENGRPGEGRNCYGKAGEDMYLIVPVGTSVFDLETNKKIGEVLNNGEILKLVSGGKRGIGNTHFKSSTNQAPRKFTLGEEGEYKEVRLELNLLADIALLGLPNAGKSTLIRSVSEATPKVADYPFTTMYPHLGVVKVGVDSFVMADIPGVIEGAAEGAGLGLRFLKHLTRARCVLHVVDICPFNESDPVENYFAVEKELKKYSEELYDKPRFLVINKIDLLADEVEEKCQEFVKQIGYEGNYYMISAAMKKGTEELAKKLNEFLHKQE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFIB_ECOLI
Sequence: MIKHLVAPLVFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAGDWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNEGLSLKRANVVADAWAMGGQIPRSNLTTQGLGKKYPIASNKTAQGRAENRRVAVVITTP
What are the official names of this protein?
Putative lipoprotein YfiB.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: E4PD_ECO81
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDTTVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_ECOBW
Sequence: MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: GET3_CANAW
Sequence: MDFELEPSLEELIKQDTLKWIFVGGKGGVGKTTTSSSIAVQLALQHPNDEFLLISTDPAHNLSDAFCQKFGKDARKVEGLSNLSCMEIDPEAAMSDLQQQAQQYNNDPNDPLKSIMNDMTGSIPGIDEALSFMEVLKHIKNQKVNESDDSKDKISYRTIIFDTAPTGHTLRFLQLPSTLQKLLGKFQQLSGKLGPMMSMLGGGGQGQQDMFAKLNEVQKNVEEVNEQFTNPDLTTFVCVCISEFLSLYETERMIQELMSYQMDVNSIVVNQLLFADDDENPCKRCVARWKMQKKYLDQMAELYEDYHLVKMPLLGSEIRGVENLKKFSKFLIKPYDPKVDRGIITDLKEQ
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting.  Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.  Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Golgi apparatus. Note=GET1 and GET2 are required for targeting GET3 to the endoplasmic reticulum.
Protein: KAD_BURM7
Sequence: MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGTPLGVEAKTYMDEGKLVPDSLIIGLVKERLKEADCANGYLFDGFPRTIAQADAMKEAGVAIDYVLEIDVPFSEIIERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLVQRDDDKEETVKKRLDVYEAQTKPLITYYGDWARRGAENGLKAPAYRKISGLGAVEEIRARVFDALK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMP_AMACA
Sequence: MVNMKCVALIVIVMMAFMMVDPSMGVGECVRGRCPSGMCCSQFGYCGKGPKYCGRASTTVDHQADVAATKTAKNPTDAKLAGAGSP
What is the function of this protein?
Chitin-binding protein with a defensive function against numerous chitin containing fungal pathogens.  It is also a potent inhibitor of Gram-positive bacteria.
What are the official names of this protein?
Antimicrobial peptide 2, AMP2.
Protein: SLE2_SOYBN
Sequence: MASRQNNKQELDERARQGETVVPGGTGGKSLEAQQHLAEGRSKGGQTRKEQLGTEGYQEMGRKGGLSTVEKSGEERAQEEGIGIDESKFRTGNNKNQNQNEDQDK
What is the function of this protein?
Late embryogenesis abundant (LEA) protein interacting with non-reducing sugars and phospholipids.
What are the official names of this protein?
Protein SLE2, Em protein, Protein Glycine max physiologically mature 11, Protein GmD-19, Soybean group-1 late embryogenesis abundant protein 2, Soybean group-1 lea protein 2, Sle2.
What is the protein family that this protein belongs to?
Belongs to the small hydrophilic plant seed protein family.
Protein: SURE_CAMJJ
Sequence: MKEILITNDDGYESEGLKKLIKMLTKEFKAKITIVAPASEKSACSHSITLTKPLRFVKVGKRFYKLDDGTPADCVYLALHALYKKRLPDLVISGINKGANVGEDITYSGTCAGAMEAVLQGIPAIALSQFYKKSEKELDYKNALQITKKIIQNIFDKGFPLEKKEFLNINFPAKSKIKGIKICKAGKRVYNFEAYSNVNPRGVEYYWLAAANLDFEDEKNSDIALLKKGYATITPIMLDLTAYERMKKVKKWLKANDE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LON_BORDL
Sequence: MKSREIEYFMEEIKDTVSKEKKRSKNSGGILPHFDKPVRVPLIAVPSHPVFPSMFIPIVIVSDIDMKAVDYVIKGNGIISLFVLRDKFLEKSGNNKDGKLTINYQKDIYSVGVTAKIVKKINLPDGGYNIFVSTIDRVKFVKVVLNEDFPIIEVDYLKQIPIKKYDVNLKAIYSSILLKTKEIFSHRKMPEFQLNMVNIEDKGRLCDVVAGMIASSKESHQEVLETLSVKDRLKKVLELLYEELNLIEIQNKIAKGIQEKLEKQQKEFFLKEQLKAIKTELGVGDEKNSEFLKMKSKIDALALKGEALDAVGRELEKFSFLERHSSEYIVVRNYLELITNLPWEDTKVDFDKFNLQRAEKILDKTHYGMREVKDRILEYISVLKLRKSQKGAIMLLVGPPGVGKTSIGAAIAEVLNTKFFRFSVGGIRDESEIKGHRRTYVGALPGKIIQGLRITKTNSPVFLIDEIDKVSSSHYGDPFSVLLEVLDPEQNVNFRDHYLDLPFDISNVFFILTANSLETIPTPLLNRMEVIQLSGYVDDEKIEIARKYLIPKVLKENGVDKDSLKFQSSSLVQIAREYARDNGLRNFEKYLKQIVRKIARKLVEDQSVKAYQISKENLEEYIGIPVFRKEKFLDKAMSPGMVMGLAWTNYGGSTLIIETVKTESKSPGIKLTGRLGDVMKESANIAFTYVNSISNELKVHKSFFEKYMIHLHIPEGATPKDGPSAGITIASAFISLALNKTVRPNLAMTGELSLTGNVMAIGGLKAKIIAAKRNGVEHIIIPKANKVDLDDIPINIKNGINFHLVDSMKEVIKLLF
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_MYCMM
Sequence: MAGRESDAVSLAGVVLAGGESRRMGRDKATLVLPGGSTTMVEHVLGIVGQRCEPVFVMAAQGQPLPPLQVPVLRDELRGLGPLPATGRGLRAAAEAGARFAFVCAVDMPGLTVDLIDDLVRSAIETDAEVVLPWDGRSHYLAAIYRTDLAERVDALVAAGERKMSALADSSDTQRIVMSDSAPLANVNTAADLPAPVRPGH
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.