PharMolix/UniProtQA huggingface dataset:
Protein: NNRD_BOVIN
Sequence: MALGPGCRAVRGCRPVLKRAFSLHKAHSVKDMESILQLVRSVVPALTTKKHKGQDGRIGVVGGCREYTGAPYFAAISALKVGADLSHVFCTQEAAPVIKAYSPELIVHPVLDSPEAVRDVEQWLPRLHALVVGPGLGRDDALLENVKGILEASKARGIPVVIDADGLWLIAQQPALIQGYRKAVLTPNHVEFGRLSEAVLGVPLDGGDRHGAVLRLSQALGNVTVVQKGEQDVISDGEQVLECSQEGSGRRCGGQGDLLSGSLGVLAHWALRAGPQKTGGPSPLLVAAFGACALTRQCSQQAFQKYGRATTTSDMVAEVGPAFRRLFEA
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase, Carbohydrate kinase domain-containing protein, NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ISPE_CAMJR
Sequence: MKAYAKANIFLKLTGFDSRKYHLLESRFILLKDVFDELELVDKESDSKKEFEIISNFKCENNIIQKAYLLLSRRYNNELKELFSKKSLKLTKNIPVCAGLGGGSSDCASFLLLINETLNLKLNLQELINLSIQLGSDIAFFLSGFHSANVSSCGEIIEEFEDDIPNLKWTFPQISCQTKAVYDEFDRGIFDFQKNNNQAQIYKKLSTKELLQNFKNKELNDLFTPCATLYPKMKSYLQEDFFLSGSGSSVFKVDR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RL362_PSEA7
Sequence: MKVLASLKQAKLRHRDCQVVKRRGRLYVICKSNPRFKCVQGRPKPKIKRR
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CCA_YERPN
Sequence: MNIYLVGGAVRDSLLNLPVTEQDWVVVGATPEQLLKLGYQQVGKDFPVFLHPVSHEEYALARTERKSGQGYTGFTCYAAPDVTLEDDLLRRDLTVNAIARSADGEFIDPYHGKQDLENRVLRHVSDAFGEDPLRVLRVARFAARFAYLGFTIAPETMSLMSNMAQSGELSALTPERVWKETEKALKTQSPHVYFQVLRDCGALAVLFPEIERLFGVPAPEKWHPEIDTGIHTLMTLAIAAQLSPEVDIRFAALCHDLGKGLTPKEHWPHHHGHGPAGVKLVEQLCQRLRIPNPVRDLAKLVAEYHDLIHTVNKLRPETLLKLFNAIDVWRKPERLEQMIMTSEADARGRTGFENNPYPQGDYLRAAFQIANGVSIQEVVASGLQGLAIRDELQRRRQQALAEWKQTQETASI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: NRDR_ECOSM
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL32_DESVH
Sequence: MAVQQNKKSRSRKGMRRSHDRVAVPAVVYCACGEPTAPHRACPSCGTYKGRQVTKQDNE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NADD_BORPE
Sequence: MGVTRIGLLGGSFDPVHVAHIALADTARQFLGLDQVQLIPAANPWQRQPLKASAPHRLRMLELAIAGHPALAINPVEIERGGATYTADTVRALPGGPQYFWLLGTDQLQNFCTWRDWQDIAARIELAVATRPGASIAPPAELAAWLAAHRRQLHELPFAPMAVSASDIRQRLAAGAATDGLLPEPVAAYIATHHLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RRF_DESOH
Sequence: MLELVYEEIEEKMGKTLEVFKNDLKKVRTGRASLALLDGIVVDYYGTPTPLNQLASLSVPESRLIVIQPWDATAIKDVEKAILQANIDLTPSNDGKVIRLSIPPLTEDRRKEIAKRVNQMAEEHKVAMRNIRRDANETLKQMKKDGDISEDESFAGKDKVQKVTDGYIERIDEVFKAKEKEILEL
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP6V1_DROME
Sequence: MVYSTNILLAIVTILTGVFIWSRRTYVYWQRRRVKFVQPTHLLGNLSRVLRLEESFALQLRRFYFDERFRNEPVVGIYLFHQPALLIRDLQLVRTVLVEDFVSFSNRFAKCDGRSDKMGALSLFLAKQPEWREIRTRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAIVSIKDVCDLYNTDMIASIAFGLRSYSLRNTQSEIGSHCQDLFRPNVRRIIDLFVIFYLPKLVPLLRPKLFTEPHAEFLRRVIQLVIEERERGGDLRNDLIEMLLTLKKEADLQQDKSHFTHHRDFLAAQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGRLTYEAVARMEFLDMVVEETLRKYPIVPLLERECTPINKKRFYSLRPHAECYTRRGMPVFISNLAIHHDPKYWPDPDRFDPERFSAANKALQAPMSYMPFGAGPRNCIGMQIGLLQIKLGLVYFLHQHRVEICDRTVERIQFDAKFALLASEQRIYLKVDCL
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 6v1, CYPVIV1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: MAP12_DANRE
Sequence: MAAPCAAQCLYRTGGLRLLQRISRLPHCHKDASLAHQCQFHRSFFWRKPKTSHSVVRPAIVRPAYPVPKHIQRPDYVSSSKVPEWPDYIEIKDEEQIQGLRRACQLARHILLLTGNSLKVGMTTDEIDFIVHQEAIRHNGYPSPLHYGGFPKSVCTSVNNVVCHGIPDSRPLQDGDIINIDVTVYLEGYHGDTSETFLIGSVNDQGRKLVDVARQCRDQAIAACGPGQPLCVIGNIISNIANSNGFRVCPYFIGHGIGEYFHGHPEIWHHANDNDLKMEEGMSFTIEPILMEGTSGFRILSDKWTAVSVDDKRSAQFEHTVVITSDGVEILTKLPEED
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase 1D, mitochondrial, MAP 1D, MetAP 1D, Methionyl aminopeptidase type 1D, mitochondrial, Peptidase M 1D.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HSLO_BACCR
Sequence: MKDYLVKALAFDGEVRAYSVRTTNTVSEAQRRHDTWRTASAALGRSLTAGTMMGAMLKGEQKLTIKVEGNGPIGPILVDAHANGDVRGYVTNPHVDFEGTEQGKLRVYQAVGTEGFVTVIKDIGMREPFIGQSPIVSGELGEDFTYYFAVSEQTPSSVGVGVLVNGDDSILAAGGFILQIMPGAQDETISFIEDRLQKIPPVSTLIEQGLSPEELLYAVLGEDKVKVLETMDVQFNCTCSRERIESVLISLGKTELEQVREEEEETEVHCHFCNERYKFSKEDITNLIENL
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_BRUSI
Sequence: MTKTVFVLNGPNLNLLGKREPGIYGVATLDDIEASCKREAGQLELQIDFRQSNHEGDLVSWIQEAGEKNAYVLINPAAYSHTSVAIHDAIRSARVTVVEVHLSNIHAREAFRHHSHVSAVAKGVICGFGAEGYLLGLRALAAIAKEEENNGQSIKGA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: ATPB_COREF
Sequence: MTTALTEQNAQQAATAGRVVRVIGAVVDVEFPRGELPALYNALTAEVTLESVAKTVVLEVAQHLGDNLIRTIAMAPTDGMVRGATVTDTGKPISVPVGDVVKGHVFNALGDCLDVPGLGRDGEQWGIHREPPSFDQLEGKTEILETGIKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMITRIAREFSGTSVFAGVGERTREGTDLFLEMEEMGVLQDTALVFGQMDEPPGVRMRVALSGLTMAEYFRDVQNQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGVLQERITSTKGRSITSLQAVYVPADDYTDPAPATTFAHLDATTELDRSIASKGIYPAVNPLTSTSRILEPSIVGERHYEVSQRVIGILQKNKELQDIIAILGMDELSEEDKITVARARRLERFLGQNFFVAEKFTGLPGSYVPLADTIDAFERICNGDFDHYPEQAFNGLGGLDDVEAAYKKLTGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CANC_DROME
Sequence: MASKYERILSDCRSKNVLWEDPDFPAVQSSVFYYQTPPFTFQWKRIMDLADSGSGAVAANSSAAPVFLNESAEFDVVPGKMGDRWLVSCLGLLSSLRNLFYRVVPADQTLASAHGVFRFRLWWCGEWVEVLVDDRLPTINGRLAFMQPQASNCFWAALLEKAIAKLHGSYEALKYGTRSDGLTDLLGGVVRQMPILSDNIRPQTLKELLTTTCIVTCLADKSATVAKKNLAERMPNGILVNVNYRLSSLDKVKTLMGDSVQLVCLKDTFSSKPFGEKTHFLGDWSPMSKTWERVSQVERARLIRQLGPGEFWLSFCDFVEIFSTMEVVYLDTETSNDEEMLKSRPLHWKMKMHQGQWKRGVTAGGCRNHESFHINPQLLISVQDEQDLVIALNQHTAVEPKVIGFTMYTWDGEYMLSECLQKDFFKNHVSYLNSDYGNTRHVSYHTHLEAGHYVLIPTTYEPAEEAHFTVRILGTGSFRLSCLETQTMILLDPFPALKSTDAERCGGPKVKSVCQYEPVYMQLADENKTINCFELHELLEACLPNDYIKGCANIDICRQVIALQDRSGSGRITFQQFKTFMVNLKSWQGVFKMYTKEKAGILRAERLRDALCDIGFQLSTDIMNCLIQRYIRKDGTLRLSDFVSAVIHLTTAFNQFHLKNYGQVNVIEVHLHDWIKSILSC
What is the function of this protein?
Not known; does not seem to have protease activity.
What are the official names of this protein?
Calpain-C, Calcium-activated neutral proteinase homolog C, CANP C.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA1_ACIGU
Sequence: YPMIPLSSLFTNAVLRAQYLHQLAADIYKDFERTYMPNEQRHSSKNSPSAFCYSETIPAPTGKDEAQQRSDVELLQFSLALIQSWISPLQSLSRVFTNSLVFLTSDRVFEKLKDLEEGIVALMRDLGEGGFGSSTLLKLTYDKFDVNLRNDDALFKNYGLLSCFKKDMHKVETYLKVMKCRRFVESNCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin-1, Growth hormone I, Somatotropin I.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LSRD_SALCH
Sequence: MNPWRRYSWEIALAALLIFEILAFGLINPRLLDINVLLFSTSDFICIGIVALPLTMVIVSGGMDISFGSTIGLCAITLGVLFQLGMPLPLAIIITLLLGAICGLINAGLIIYTGVNPLVITLGTMYLFGGSALLLSGMAGATGYEGIGGFPTAFTDFANISFLGIPMPLIFFLVCCLFFWLLMHRTHMGRNVFLIGQSARVAQYSAIPVNRTLYTVYAMTGCASAIAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIMGSALAALLVGFLQQGLQMAGVPNQISSALSGALLIVVVVGRSVSLHRHQILEWYSRRRNAHQA
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIBB_ECO57
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: KAD_HALH5
Sequence: MNLILMGLPGAGKGTQAEKIIEKYGIPHISTGDMFRAAMKNETELGLKAKSYMDAGELVPDEVTIGIVRDRLSQDDCQNGFLLDGFPRTVAQAEALEDILASLDKKLDYVINIDVPEQLLMDRLTGRRVSPTSGRTYHVIFNPPKVEGICDVDGSELIQRDDDKPETVKKRLEVNQKQAQPLIDFYSEKGYLQNINGDQDISRVFEDINELLKGLSS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
Protein: IF2_BACMK
Sequence: MSKIRVHEYAKKNNISSKDLMTKLKEMNIEVSNHMTMLEDEVVNKLDNQYSAGAEKPSVADEFEVEEKVVRSKKNSNKNKKKGKANEDKRQDNFAGRQQTPIVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIATDYGIEVEEEVVVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVDVNDKKITFLDTPGHAVFTTMRARGAQVTDITILVVAADDGVMPQTVEAISHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYAAGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTSFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALVAQRGEKSKFSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELEKVDVRLHRIIYKVIEEIESAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVIDGKITRDSGVRIIRDGVVVFEGKLDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYVMEEVKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_BACCQ
Sequence: MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEIDAEEIVKEAEIVFLATPAGVSAELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRAAAKEEILSKAVYGLSEWKRSEVQNANLIANPGCFATAALLATLPLVRSGIIEEDSIIIDAKSGVSGAGKTPTTMTHFPELYDNLRIYKVNEHQHVPEIEQMLAEWNRETKPITFSTHLIPISRGIMVTLYAKVKREMEIEQLQKLYEETYEQSPFIRIRLQGEFPSPKEVRGSNYCDMGIAYDERTGRVTVVSVIDNMMKGAAGQAIQNANIIAGLEETTGLQHMPLYL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_YERPY
Sequence: MKVGIIGAMEEEVTLLRDRIENRQTLARAGCEIYTGQLNGIDVALLKSGIGKVAAAMGTTLLLEHCQPDLVINTGSAGGLASSLKVGDIVVSNEVRYHDADVTAFGYEPGQMAGCPAAFVADEDLIALAENCIQQLKLNAVRGLICSGDAFINGAEPLARIRAAFPTVAAVEMEAAAIGHVCYLFNTPFVVVRAISDVADQASHLSFEEFLVVAAKQSTLMIEAMLTTLAQRG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: UBQL_CAEEL
Sequence: MATESALIKVHVKSPSNKYDVEIAADASVSELKDKVLVFVPTANKEQVCIIYTGKILKDEETLTQHKIADGHTVHLVIRNQARPTPAPAAATPTASSAPSSNPTPSSQPNPTNNPFAAMGGMGSPADILNNPDAMRSVMDNPITQQLLGNPEFMRTIIQSNPQFQALIERNPEVGHILNDPNVMRQTMEMIRNPNMFQEMMRNHDQAIRNLQGIPGGEAALERLYNDVQEPLLNSATNSLSGNPFASLRGDQSSEPRVDRAGQENNEALPNPWASNANQATNNQSNNRSADFNSLLDSPGISSLMEQMMSNPSMQASMFSPEVINSIRQNMSNNPGLIDSIVGQIPSARDNPQISEGIRRSFPQMLNMMSDPSVMEAMRNPRVSEAFRQIQEGFSTLRREAPQLLNLFQAGAMGGGAFGSDANASSAGANSANGLADLFNSMNMGGGRPSSTAAPVNPEQTYASQLEQLQSMGFSDRARNVAALTATFGDLNAAVERLLNSP
What is the function of this protein?
May play a role in the ER-associated protein degradation pathway (ERAD) possibly via its interaction with ER-localized proteins ubxn-4 and cdc-48. 1 and/or cdc48. 2, providing a link between the polyubiquitinated ERAD substrates and the proteasome (PubMed:19822669).  Also plays an important role in the regulation of other protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS) and autophagy (By similarity).  Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome (By similarity).  Collaborates with POST (F36D4. 5) in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234).  Also acts as a regulator of DNA repair by inhibiting homologous recombination repair, thereby redirecting double-strand break repair toward non-homologous end joining (NHEJ) (PubMed:30612738).
What are the official names of this protein?
Ubiquilin.
Protein: GELLY_BACSP
Sequence: MRFSWKKLVSAALVMALLVGIVYPAASGRGAVASAASGTTVELVPTDDAFTSAVAKDANANGTWMQLKGSIGGQRYIYMKFDLTALAGVEADRIENAKVWLKKMGTNGTAMTVGLRAVDDTSWSESTLTWNNAPVYGSQVLSQQSVLSTPDVYYPFDLDEYLKTQLAAGKSKLAIAFVPISTLNENMEFYARESTANTPKLVVELKDEPPAPTGLMQLVQSFGGHNKGHLRVVEFDATPASTTGNGTVGITADGAAPAAAADFPIALRFGTDGTIKAANAAGFESKTPVNYTAGQKYHVKAMINLSLGTYDLWLTPPNAGQPVLLAADYAFAASAPALNDIGGVHATADAQSTDVPAVANARLIADHFVSKAPFKDEQGQSLAIRLESDNSLANRSYAIKFDMNLTGNPLETDALISYADRSVTLNGFPDLAYIVRSNFGNFDVRNDNVYASSHPSTAQSNRTYQVEVRINPASGTGQPTRTYDVWIAPEGEQPVQLADQFKARNYANTGYALNNIGQAFVYSQADGLLSIDNHVVQDGQRLDEALARVNAASGEAAMTAALESNALGLPMERYRLMDAAKRAQVAQDVLAGRPAEGYAHALSVQAVFVSAVANRLDTENPTAPANVQVAISNTMQAHVSWTASSDDTGILYYKVFRDGALVGTVTNATSFVDNGLAPATEYTYVVKAYDLVLKEAVSQPATATSPGEQAQVRIPFSAEAIATAFGQPLLDYNLETHSGTLKWVMEWREEYEKSANALKLLTLLSASAPDYIGPDGVTTASAKALQHLRSVTAGGNEPGFAGNGLSGQGYMPLLSAIVMAKKKAPAIWNALTAAEKEKLDLMILAGLYGAKFAYDDENDNKTGIDATGNFDKEWNPNHRSGIAGAIMAMYYFEDAQWLNDQMRSFNYDDWLARLTAAGLTNVRTIYQNSGKTLTEREIRKDAAGDGFVYKGHPLSQPGKIMAEFVNYTFSHPVSPVGGFDSGIGKYRGYIVDGQDDLPNLGADSMGFEFDTLDANGKRSSLVYVFMGWKPNVDAITPVLLLDNIDSGLTSAETRDVVSRLSIGTTDMLYKNEHGYMTYAKGVNEGVKSLNGPILTINEEIWNRILNNPAAPMEAVNQASSAGQMRTALEASALGMILYGYGALSETGKNAVAQHVLDARPAAGYANKAAAQNELYEGVRLQALLALSQAQTAEQMRSALESRALGLYKPKYETASQDKKQFVAQYLLDNKPADGFLTKTEVREQVESALEPQGNQLRNLPPLASGEKRINLADYDHWPQQHGDAEVALWADDKTGAFSLTIDDNFENEHDTWRSLAQQYGFKFSWFVITSLIKDPNKWRTLAAEGHEIGSHTVTHEDKGSTLDPAHLHSEYADSQALLNTIEGVRATTLAYPFGSGREDIAAEYYIAARGTVGLPNPADSINYMNTQSLSVRPGSLELTNQAANGNSVEAMVKTLVDPNHKVWSASYYRGWSNMLVHSLNESGKTPSDGVTRTSRDLTQYLLTLLDTYRDQIWVGRYGDIVRYSQQRDTAHIVVTRKDDRKITFNLTDRMDDTLFDYPLTVKVRVDDAWSDIGATQAGEPIPFVETIRDGKRYLLVKAVPDKGSVSIVPDAASPLNVVNGAVTSEQMLSAIAAPGLGLDLGEFNALGAGKKRMVGSRLLEVRPADGYADAAALQDALDAAVEEANNAPSLSENASLSDLKVNGVTIAGFAPETYAYDIMLPEGTTALPVVSFKVADTGKATAVLQNAPALPGTAKVTVTAEDNWTVATYTLRFQVRISALQRVNTAPDASAMRTAIENAALGLVLAAYNGLTSEQKNSVAASVLTHRPATGYADVQAVQAELNAALPKINAPLLAHAIVDQLNPDTVSTANWTNLYGGTSGRKGGVYMKFNIASLAGLEADAIGDAKVQFFTTREGTVIGYAAPSSWEAPLTWNTQPLADLKNSNMAALAEIGRTAVQATGANYEMNITQYVKDAAAADKTELSLVLLGSNNTNITMQKIPTAFALSVTLATYGEPNPEPSPLAAVNEAGDAAAMQGAIAAVELDLNLTAYNGLTAAQRIDVAQALLDNRPAAGYAHALAVQVALDAAVAAAQPANQAPGGTLAASAEQLQPGQQLELTVGVSDASRFTGADILVHYDPQALTFATELYEGVRMLKAEAIASLQANYQVAAAMAEQPGTIKILLFTAGAGQPLSGTLPLFKLRASVKDDAQTGVSTAVSLSDFELTFEGEDSVWPDTTRAAVSLQIAAHPVEADKTALIAKIAHAQALLTGATVGANPGQYPQAAYDALADAIGLAEEKRDLTGVSQAAVDEAVASLGTAEQQFLNAVIPGVPADLTALNAAIAKAQRLHDNGPYGEKIGQYPQSAKVPLKSALDAAKAVGGSGASSQESVNAAAASLNGAIQTFERSLVTLVGGGATKVGIRDLSIVAKYYGVTSSDPNWGKVSAAAIDGGNEITIEVLAAVARMILADWAAGQ
What is the function of this protein?
Cleaves the glycosidic bonds of gellan backbone and releases tetrasaccharide units of glucuronyl-glucosyl-rhamnosyl-glucose with unsaturated glucuronic acid at the non-reducing terminal.  The enzyme is highly specific to the heteropolysaccharide gellan, especially deacetylated gellan.
What are the official names of this protein?
Gellan lyase.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3143_PYRAE
Sequence: MTVPRVRSYVPGLDEILFGGIPERSVVLLSGGPGTGKSILGKQFLYNGLKRGDAGVFVALEEHPVAVRRSFRHFGWDIAQYEREGKFAIVDAFTGGVGTAAQRERYIVKQVDDVHELSDVLRQAIRDTGARRVVIDSVSTLYLTKPAVARGTIMTLKRVIAGLGCTAFFVSQVSVGERGFGGPGVEHAVDGIIRLDLDEFDGRLYRSIIVWKMRDTKHSMVRHPMEIKDGGIEIMWDKYIKITGSSVRIEPLPKEEAEAMRKAVEDVEKQPAPKKIEIEEE
What are the official names of this protein?
UPF0273 protein PAE3143.
What is the protein family that this protein belongs to?
Belongs to the UPF0273 family.
Protein: EFTS_UREU1
Sequence: MTKAELVKELRTRTQASMSECIKALDASENDIEKAIIWLRENGAIKAANKLKNAATDGVTLAKKVGNKAILIEVNCQTDFVAKNENFLAYANQILEEALAKVESKEDFDKLIINGKPIAESGLDLTAYIGEKIVFRRGEILKANDQQTLGVYTHNNNRVAAIILVDGKVEDEVVRNVAMHAAAMRPRYLNEQVVDQVWLAKEREIIVNQLEHEGKPAAFAAKIIEGRLNKILKENCLVDQSYFKQPELTIEKYLKNNNAVAVGYYSYEVGEGIEKAPQMSFADEVAAQMKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R27AB_ORYSJ
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHKHKKVKLAVLQFYKVDDATGKVTRLRKECPNNDCGAGTFMANHFDRHYCGKCGLTYVYNQKA
What is the function of this protein?
Ribosomal protein RSP27a-2 is a component of the 40S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a-2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.