PharMolix/UniProtQA huggingface dataset:
Protein: RS12_XANP2
Sequence: MPTINQLIRKPREAQKARDKAPALQASPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNSYEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHILRGVLDTQGVKNRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MYL3_RAT
Sequence: MAPKKPEPKKDDAKTAAPKAAPAPAAAPAAAPEPERPKEAEFDASKIKIEFTPEQIEEFKEAFQLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMAS
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium.
What are the official names of this protein?
Myosin light chain 3, Myosin alkali light chain 1, ventricular, MLClV, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB, Ventricular myosin light chain 1, rVMLC1.
Protein: RPN5_YEAST
Sequence: MSRDAPIKADKDYSQILKEEFPKIDSLAQNDCNSALDQLLVLEKKTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHGQLKLSIQYMIQKVMEYLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIKKEEGKIDEAADILCELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKKTFKNPKYESLKLEYYNLLVKISLHKREYLEVAQYLQEIYQTDAIKSDEAKWKPVLSHIVYFLVLSPYGNLQNDLIHKIQNDNNLKKLESQESLVKLFTTNELMRWPIVQKTYEPVLNEDDLAFGGEANKHHWEDLQKRVIEHNLRVISEYYSRITLLRLNELLDLTESQTETYISDLVNQGIIYAKVNRPAKIVNFEKPKNSSQLLNEWSHNVDELLEHIETIGHLITKEEIMHGLQAK
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit RPN5, Proteasome non-ATPase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit p55 family.
Protein: RETR1_BOVIN
Sequence: MASPAPPEPAEQGSPALAAAPQAPPPPTRAPPEEPEGAAPPEEGAAAGAGRQVEEAAGGVAAVVTWLLGEPALWLGGRADELLSWKRPLHSLLAFVGANLVFWFLALTPWRVYHLISVMILTRVIMQIIKDMILSRTRGAQLWRSLSESWEVINSKPDERPGFSHCLAESWMNFSIFLQEMSVFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLCAFLCPLFKCNDIGQKIYSKIKSCLLKLDFGIREYINQKKRERSEADKEKSHKDDSELDFSALCPKISLTTAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPSEEVFSRDLSDFPSLENGTGTNDEDELSLGLPTELKRKKEQLDGGPRRSTEKKSAAGLSLPLSSDQTLHLMSDLAGDVITAAVTAAVKDQLAGVRQALSQAAPSLGEDTDTEEGDDFELLDQSELDQIESELGLSQDQEAEAQQNKKSSGFLSNLLGGH
What is the function of this protein?
Endoplasmic reticulum (ER)-anchored autophagy regulator which mediates ER delivery into lysosomes through sequestration into autophagosomes.  Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins.  Active under basal conditions.  Required for collagen quality control in a LIR motif-dependent manner.  Required for long-term survival of nociceptive and autonomic ganglion neurons.
What are the official names of this protein?
Reticulophagy regulator 1, Reticulophagy receptor 1.
What is the protein family that this protein belongs to?
Belongs to the RETREG family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IFNA3_HORSE
Sequence: MALPVSLLMALVVLSCHSSCSLGCDLPHTHSLGNTRVLMLLGQMRRISPFSCLKDRNDFGFPQEVFDGNQFRKPQAISAVHETIQQIFHLFSTDGSSAAWDESLLDKLYTGLYQQLTELEACLSQEVGVEETPLMNEDSLLAVRRYFQRIALYLQEKKYSPCAWEIVRAEIMRSFSSSTNLPQS
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-3.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAD_MYCTU
Sequence: MIKVNVLYFGAVREACDETPREEVEVQNGTDVGNLVDQLQQKYPRLRDHCQRVQMAVNQFIAPLSTVLGDGDEVAFIPQVAGG
What is the function of this protein?
Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin (By similarity).  Probably plays a role in host phagosome maturation arrest (PubMed:20844580).
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit.
What is the protein family that this protein belongs to?
Belongs to the MoaD family.
Protein: ATPB_STRPG
Sequence: MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIVLEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDLEEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVADTVRGFKEILEGKYDDLPEDAFRSVGPIEDVIKKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DPS_SALTY
Sequence: MSTAKLVKTKASNLLYTRNDVSESDKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALTDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHNVQDHLKELADRYAVVANDVRKAIGEAKDEDTADIFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_LEIXX
Sequence: MDDDLALQRAVALRSGLDDYELDDADLDLLEVDGEDADAIAFLPALPVLAIVGRPNVGKSALVNRILGRREAVVEDTPGVTRDRVSYRAEWNGRRFTVVDTGGWEPDARGIDASVAAQAEVAIDLADAVMFVVDAMVGATSTDEHVVRLLRKSDKPVFLAANKVDDARQEPSATELWSLGLGEPHPVSALHGRGVADLLDKILKALPDVSAVAKQEVGGPRRVAILGRPNVGKSSLLNKAAGEERVVVNELAGTTRDPVDEQVELGGRVWRFVDTAGIRRRVHLQQGADFYASLRTSTALEKAEVAVVVLDVSQPISEQDVRIIDLVLESGRALVLAFNKWDLLDDERRRYLEREIEQDLAHVSWAPRVNISARTGRHLEKLVPALERALESWETRIPTGKFNAFLAELTSAHPHPVRGGKQPRILFGTQSTSRPPTFVVFTTGFLDPGYRRYVIRRLREVYGFEGTPIVLNMRVREKRKH
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TOMB_ECO57
Sequence: MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRKSGNRLFRCFVNATKENPASLSC
What is the function of this protein?
Attenuates Hha toxicity and regulates biofilm formation.  Binds to various coding and intergenic regions of genomic DNA (By similarity).
What are the official names of this protein?
Hha toxicity modulator TomB.
What is the protein family that this protein belongs to?
Belongs to the TomB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL38_HUMAN
Sequence: MPRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKEKAEKLKQSLPPGLAVKELK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L38, Large ribosomal subunit protein eL38.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL38 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTAP2_HUMAN
Sequence: MVVGTGTSLALSSLLSLLLFAGMQMYSRQLASTEWLTIQGGLLGSGLFVFSLTAFNNLENLVFGKGFQAKIFPEILLCLLLALFASGLIHRVCVTTCFIFSMVGLYYINKISSTLYQAAAPVLTPAKVTGKSKKRN
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (PubMed:22467853).  May be involved in N-glycosylation of APP (amyloid-beta precursor protein).  Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1 (PubMed:21768116).
What are the official names of this protein?
Keratinocyte-associated protein 2, KCP-2, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2, Oligosaccharyl transferase subunit KCP2.
What is the protein family that this protein belongs to?
Belongs to the KRTCAP2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TMED8_MOUSE
Sequence: MSDRQAAEGPAFWSPAARRGSAGGVGDRRGVEESQAAASEKEDLESTNVSSPLASASDPAAESSPYRPQMVSPASKDTTEDLQNVAGASEGQAPGEQAALPAGQTQVLSEMAKYQAPQRPEDTVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCVWTFAKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSEDEEEEEDEEEEIEEPVPVGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHIYYTS
What are the official names of this protein?
Protein TMED8.
Protein: SPNE_DROYA
Sequence: MDQDVMDFFDFSKEFKREVAPQGYISSDPKMMATDSIDSKVPKREVIGTEYVTEIVAKEKGLLNRTLRDECPQSKRKHTLDDLDTDDEEEETEIRRDDEYYKKYRFNLNRDKNLPIYAKREEILAAINANPVVILKGETGCGKTTQVPQYILDEGYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQDTVCSYQVGLHRPTSLEDTRLLYCTTGVLLNNLIRNKTLTHYTHIVLDEVHERDQDMDFLLIVVRRLLATNSRHVKIILMSATIDARELSDYFTTTNSIPPVISASHGRKHSIEKFYRDQMGSIKWKEEEDDQLVPQINDHGYRAAVKIIMVIDNMEREGAIHSRMSYDEALRYGAVLIFLPGIYEIDTMAENITLMLENDRNVKVFIVRCFSLMTPENQRDVFHPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLTKVLVTDTATNFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKSFYQREMSEFGIPEMLRLPLQNSVLRAKELEMGSPVEILALALSPPNLSDIQNTILLLKEVGALFLTVDGVYNAMDGDVTYWGTIMSRLPLDPRLSRLIILGYVFNLLEEAIIMAAGLSMRGLYVHEGSSSRSTRAQFDSFWMHYIFADGSGSDLVAIWRVYLTYLNMVEIGHEQESAIRWANRFHVSLRSLKEMHLLVQELRVRCTNLGLIPFSVNPSQIMDDREKSFILKVIIAGAFYPNYFTRSKEMWNEHDRHIYQTISGHDPCRTVYFTNFGPSCMGELYTRRIKDFFHDARIPPENMDVTFQPGSEKVFVTFKQDDCVADSSKLVSVPGRVQSEVYKAVRMRLSCMQRIIRIMRPKQFMNYVQERGIGDVIEGRWIPPTKPLNVELLALPSVFSKTITGLITGIINCGKFYFQPLSLAECIRNMSEIFNAPQQLRKYVVDACDISKGMMVLAKRDSNFQRATVIRPENQSNRQPMFYVRFIDYGDCALLPMQQLRFMSEELIQQYGDLPPRVFECRLALVQPSSMVHGNYSWPTAANDLLQFVAKCGRIDIEVYSLFNNVAAVLIHMRNGTINDKLVAQKLCRRSDEDYMSRKDHDFRLRSQESGRYLSSAERQQINEEYLRSCQLPQDFDLPPPPQDLCGTNVRLKGPYSPLECSMQSIIRVGSSKRVNIDSASVNAVLLDTDPQDHHDHLIVAHATVESPNGQTLTARGTTLMPNVQGYGALMVMLFCPTMQLKCNEEGTSYVSILAGLGCDPVTGEPYYAEHDVLINLDVNILEDDLVLINQIRYYIDSVFFNFKEENYPAVSVNERESIYTQLRSLIKRLLSKDRSYIGKNMSNSDFVWETNPELPMPNEPFGKRAIFPMHSLTELKEDDMGRLMNLRENCSMLHKWRNFEGTLPHMTCKLCNQLLESVPQLRLHLLTILHRDREKQIDFCNQ
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons.  Involved in the repression of LTR retrotransposon copia.  Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements.  Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin.  Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats.  Required for anteroposterior and dorsoventral axis formation during oogenesis (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E, Homeless.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: HIS6_HELMO
Sequence: MLAKRIIPCLDVHGGRVVKGTNFVNLRDAGDPVELAAVYDKEGADELVFLDITASSDGRAIMLDVVRRTAEEVFIPFTVGGGLRTVEDIREMLKAGADKISLNTSAVQTPQLIGDSAWKFGSQCIVVAIDARRRRDEEGRLLEGWEVYTHGGRKPTGIDVLEWARKVEELGCGEILLTSMDKDGTKDGYDIPLTRAVSEAVKIPVIASGGVGNLEHICEGLTAGKADAALAASIFHYKEYTIRETKEYLRGKGVHVRKWRD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_STAA2
Sequence: MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDIYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRIEEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_RHOP2
Sequence: MNQEIMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGQLLDMTLKDLERILYFEYYVVLEPGLTDLKERQLLSEEEYLRAQDQYGQDSFTAMIGAEAIRELLKGLELEKIDAQLRVEMAETDSDIKHKKLAKRLKIVEAFRFSGNKPEWMILTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSILREGLPGEGKVFGDLAELEHALFSKVIHLHTKIKYRWDSLDDEGKPYQRLIETTAGRILLGQVLPKSVKLPFEVINKLMTKREISSVIDQVYRHCGQKETVIFCDRIMALGFFNAFKAGISFGKDDMVVPASKWKIVDTTRTLAKDFEQQYNDGLITHGEKYNKVVDAWSKATEEIAKEMMKEISAVRKNASGAETQVNSIYMMAHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITQDDCGTSLGIKMRAIIDAGTVVASLGSRILGRTAGEDVRDPQTNEVIVKKGQLMEERDVEAIHQAGVQEVKIRSALTCELVNGICGKCYGRDLARGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQINEQSVIESNFEGKVVIKNKAIARNGENHSVAMVRNMVVAIVDPDGTERATHRIQYGARMHVDEGDTVKRGQRIAEWDPYSRPVLTEVEGTIDFEDLVEDQSISETLDESTGIAKRIVIDWRSTRGGADLRPAIVVKGKDGKVLKLARGGDARYMLSVDAILSVDVGAKVKPGDILARISTESAKTRDITGGLPRVAELFEARKPKDAAIIAEIAGTIRFGRDYKNKRRISIEPMDSEEEAREYLIPKGKHIHLQDGDIVEKGDFIVEGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITDQGETDMISGEQIDKIEFDQLNAKARDEGKKIATGTPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGASMAKLREVAMKRDRMILDEREKQATIVPPAAPEAEPLALPPVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MPHES_MICSP
Sequence: SATAAREEYQRKRSQFIEIG
What is the function of this protein?
Probably involved in the metabolism of xenobiotics and of natural substrates.  Hydrolyzes medium-chain monoalkyl phthalate esters.
What are the official names of this protein?
Monoalkyl phthalate esterase.
Protein: RL16_SHESR
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGTFGLKAVGRGRLTARQIESARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMNGVSEVIAREAFALAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PG067_VACCC
Sequence: MLILTKVNIYMLIIVLWLYGYNFIMSGSQCPMINDDSFTLKRKYQIDSAESTMKMDKKRTKFQNRAKMVKEINQTIRAAQTHYETLKLGYIKFKRMIRTTTLEDIAPSIPNNQKTYKLFSDISAIGKASQNPSKMVYALLLYMFPNLFGDDHRFIRYRMHPMSKIKHKIFSPFKLNLIRILVEERFYNNECRSNKWRIIGTQVDKMLIAESDKYTIDARYNLKPMYRIKGKSEEDTLFIKQMVEQCVTSQELVEKVLKILFRDLFKSGEYKAYRYDDDVENGFIGLDTLKLNIVHDIVEPCMPVRRPVAKILCKEMVNKYFENPLHIIGKNLQECIDFVSE
What is the function of this protein?
Major early protein present in virus factories.  The presence of BEN domains suggests a possible role in organization of viral DNA during replication or transcription.
What are the official names of this protein?
Protein OPG067, Protein E5.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG067 family.
Protein: CRVP_ERYPO
Sequence: MIVFILLSFAAVLQQSFGRIDIDSQSTRRPEIQNLIVDTHNSYRRSVSPTATNMLKMEWYPEAAANAERWAYQCVYDHSQKYERVLDGIQCGENIYMYSEFRPWTEVMQSWYDEYRNFIFGVGAHPANALIGHYTQIVWYKSYRVGCAIANCPSYPYNYFYVCQYCPAGNFGGQTATPYNSGTTCADCPSACDNGLCTNPCTSENVFTNCNDMVKESGCQDERMKSICPASCF
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein LIO1, CRVP, Cysteine-rich secretory protein LIO1, CRISP-LIO1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: F6H12_IPOBA
Sequence: MPAVLSSVLSNITDFVVHEGNGVKGLADMGLEALPKQYVQPEEERITTSTVIVDDTIPVIDLSEWGSDPKVGDMICEAAEKWGFFQIVNHGVPLEVLEEVKAATYRFFRLPAEEKNKHCKDNSPSNNVRYGTSFTPHAEKALEWKDFLSLFYVSDEEAAALWPSACRDEALTFMRNCDAVIKRLLKSLMKGLNVTEIDGTKESLLMGSKRINMNYYPKCPNPELTVGVGRHSDVSTLTILLQDQIGGLYVRKLDSDTWVHVPPINGAIVINVGDALQILSNGRYKSIEHRVIANGSNNRISVPIFVNPRPNDIIGPLPELLESGEKAVYKNVLYSDYVKHFFRKAHDGKETVDFAKIN
What is the function of this protein?
2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD) involved in scopoletin biosynthesis (PubMed:22169019).  Converts feruloyl CoA into 6'-hydroxyferuloyl CoA, and, at low efficiency, caffeoyl-CoA into 6'-hydroxycaffeate, but has no activity with p-coumaroyl-CoA (PubMed:22169019).
What are the official names of this protein?
Feruloyl CoA ortho-hydroxylase F6H1-2, IbF6H1-2, 2-oxoglutarate-dependent dioxygenase F6H1-2, 2OGD F6H1-2.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: TRUB_RALSO
Sequence: MTEQRPSQQAKQPRRDVHGVLLLDKPIGWSSNDALIRAKRLLWAKKAGHTGTLDPLATGLLPLCFGEATKFSQDLLEADKTYEAVVRLGIRTSTADAEGEVLSERPVAVTPEQLRAAIGRFVGEIDQVPPMHSALKKDGKPLYEYARAGQTVERAARRVTIRAIDVLATDLDAAAPTVTLRVCCSKGTYIRTLGEDLGEALGCGAHLVALRRTQVGSLTLDGAVTLEALEAASEDQRAALLAPVDALLQTLPRVELGAEDSRRFLHGQRLPLQLSLPSAEQVRVYGARGEAGASLLGVAAWQGGVLRPERLVHL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: PIMRE_HUMAN
Sequence: MASRWQNMGTSVRRRSLQHQEQLEDSKELQPVVSHQETSVGALGSLCRQFQRRLPLRAVNLNLRAGPSWKRLETPEPGQQGLQAAARSAKSALGAVSQRIQESCQSGTKWLVETQVKARRRKRGAQKGSGSPTHSLSQKSTRLSGAAPAHSAADPWEKEHHRLSVRMGSHAHPLRRSRREAAFRSPYSSTEPLCSPSESDSDLEPVGAGIQHLQKLSQELDEAIMAEERKQALSDRQGFILKDVYASP
What is the function of this protein?
During mitosis, may play a role in the control of metaphase-to-anaphase transition.
What are the official names of this protein?
Protein PIMREG, CALM-interactor expressed in thymus and spleen, PICALM-interacting mitotic regulator, Regulator of chromosome segregation protein 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Partially localizes to the nucleolus.
Protein: HCP_CLOBJ
Sequence: MSMFCYQCQEAAGGRGCTVKGVCGKTEDIAKTQDLIIYVVKGIAIYSSQAREMGLNTSEADKFIVESLFSTITNANFDAKALNARVQKGLKIRQSLKDAIIKAGGSYNSKENKSWTSKFLSVLGIKNDKDEKEIHDAAVWAANNPEDFKKKAETVGVLATENEDIRSLRELLTYGLKGMAAYLEHANNLGYDEDSIHAFMEKALVATLDDTLSADELTALVLECGKYGVDVMALLDKANTSTYGNPEITKVNIGVRNNPGILISGHDLKDMEELLKQTEGTGVDVYTHSEMLPANYYPAFKKYKHFVGNYGNAWWKQNEEFEAFNGPILMTTNCIVTPKASYKDRMYTTGVTGFEGVKHINTSKDGKKDFSEIIEHAKRCTSPKEIEKGEIIGGFAHNQVLALAPQVVDAVKTGAIKRFFVMAGCDGRMKSRNYYTDFAKALPKDTVILTAGCAKYKYNKLDLGDINGIPRVLDAGQCNDSYSLAVIALKLKEVFELEDINELPISYNIAWYEQKAVIVLLALLHLGVKNIHLGPTLPAFLSPNVAKILVENFGIGTISSVDEDIKMFMN
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_SALPK
Sequence: MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.