PharMolix/UniProtQA huggingface dataset:
Protein: FUS7_GIBM7
Sequence: MNFDTFHNIIAGQHRSARETSSGVNPLDRSSLWPAPVATANDVEEAVRSAQEAFPAWSQKTYKQRTELLEKFADLYLAHANEFCQLIATECGRTAGNAAIEVYFAAQWLRYPSKYEISQEITEDDKKTSIVTQEPLGVVAAICPWNFPLMLALGKIAPALATGNCVILKPSPFTPYSSLKLVELAQQVFPPSVLQVLHGHDDLGPMLVKHSRIQKITFTGSTATGKQILRDAAETMKRVTLETAGNNASIILPDVNIKAVIPQLAGGLWFNAGQVCIATRRMYIHQDIFEEVVAQLAEASKDLTSSIEPIQNEMQLVRLKQALADANAAGYELLSLGKTEAAEGFFIRPTIIKNPPPDAHAVQQENFGPIVSCIKFSSLDEAIFLANNSDTGLAASVWSGDISAAKRVAAKLEAGNVYINGPPQPDPYVPFGGQKQSGLGVEYGLPGLLSFCQTKSTYVYK
What is the function of this protein?
Putative aldehyde dehydrogenase; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:22652150).  Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (By similarity).  The other FUS cluster members are not essential for fusarin C biosynthesis (By similarity).
What are the official names of this protein?
Putative aldehyde dehydrogenase FUS7, Fusarin biosynthesis protein 7.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: ARP6_ORYSJ
Sequence: MTGGSGVVVLDNGGGLLKAGFGGDMNPTAVVPNCMAKPPGSKKWLVADQLQAQDVDVTGMTLRRPIDRGYLINQEVQREVWERVIRNLLQVDPNNSSLLLVEPQFNPPALQHATDELVFEELGFKSLCVADAPSLVHLYEASRQPSLFRAQCSLVVDCGFSFTHASPVLQNFTLNYAVRRMDLGGKALTNYLKELISYRSLNVMDETLLIDDAKEKLCFVSLDVPGDLRLARLSSNDNPFRCSYILPDGITYKKGFVKDLDEACRYSSLPANGESVRKDSSDSDRSKFEDKKKPELSQNEFVLTNERFLVPEMLFHPIDLGMNQAGLAECIVRAIQACHPHLQPVLFERIILTGGSTLFPRFTERLEKELRPLVPDDYQVKIIAQEDPILGAWRGGSLLAHRPDFESMCITKSEYEEMGSMRCRRRFFH
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A. F/Z leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in several developmental processes.  May be involved in the regulation of pathogenesis-related proteins (PRs) (By similarity).
What are the official names of this protein?
Actin-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENGB_YERE8
Sequence: MTIRNFNYHMTHFVISAPDIRHLPRDEGIEVAFAGRSNAGKSSALNTLTGQKSLARTSKTPGRTQLINLFEVVEGVRLVDLPGYGYAEVPEEMKLKWQRALGEYLQKRNCLKGLVVLMDIRHPLKDLDQQMITWAVAVGTPVMLLLTKADKLASGARKAQLNMVREAIIPFMGDIQVEAFSSLKKIGVDKLREKLDTWFSEIPPEVMIDEYDDEEGK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ADH3_KLULA
Sequence: MLRLTSARSIVSPLRKGAFGSIRTLATSVPETQKGVIFYENGGKLEYKDIPVPKPKPNEILINVKYSGVCHTDLHAWKGDWPLPTKLPLVGGHEGAGVVVAMGENVKGWNIGDFAGIKWLNGSCMSCEYCELSNESNCPDADLSGYTHDGSFQQYATADAVQAARIPKGTDLAEVAPILCAGVTVYKALKSANLKAGDWVAISGAAGGLGSLAVQYAKAMGYRVVGIDGGEEKGKLVKQLGGEAFVDFTKTKDMVAEIQEITNGGPHGVINVSVSEAAMNASTQFVRPTGTVVLVGLPAGAVIKSEVFSHVVKSINIKGSYVGNRADTREAINFFANGHVHSPIKVVGLSELPKVYELMEQGKILGRYVVDTSN
What are the official names of this protein?
Alcohol dehydrogenase 3, mitochondrial, Alcohol dehydrogenase III.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TSR3_YEAST
Sequence: MGKGKNKMHEPKNGRPQRGANGHSSRQNHRRMEMKYDNSEKMKFPVKLAMWDFDHCDPKRCSGKKLERLGLIKSLRVGQKFQGIVVSPNGKGVVCPDDLEIVEQHGASVVECSWARLEEVPFNKIGGKHERLLPYLVAANQVNYGRPWRLNCVEALAACFAIVGRMDWASELLSHFSWGMGFLELNKELLEIYQQCTDCDSVKRAEEEWLQKLEKETQERKSRAKEEDIWMMGNINRRGNGSQSDTSESEENSEQSDLEGNNQCIEYDSLGNAIRIDNMKSREAQSEESEDEESGSKENGEPLSYDPLGNLIR
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA (PubMed:27084949).  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA (PubMed:27084949).  Required for processing 35S pre-rRNA at site D (PubMed:19806183).
What are the official names of this protein?
18S rRNA aminocarboxypropyltransferase, 20S rRNA accumulation protein 3, ScTsr3.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DUS1_BACSU
Sequence: MFKIGDIQLKNRVVLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILYNNARTMGMLYIDEREKPLSLQIFGGKKETLVEAAKFVDQNTTADIIDINMGCPVPKITKCDAGAKWLLDPDKIYEMVSAVVDAVNKPVTVKMRMGWDEDHIFAVKNAQAVERAGGKAVALHGRTRVQMYEGTANWDIIKEVKQSVSIPVIGNGDVKTPQDAKRMLDETGVDGVMIGRAALGNPWMIYRTVQYLETGKLKEEPQVREKMAVCKLHLDRLIDLKGENVAVREMRKHAAWYLKGVKGNANVRNEINHCETREEFVQLLDAFTVEVEAKELQNAKVG
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase 1.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: LEUD1_THEMA
Sequence: MIRGRVWKFGDNISTDHIAPGRYFHLRNNLEELAKHVLEDAMEDFAKKVQKGDIIVAGKNFGLGSSREHAARIIKIAGVSCIVAKSFARIFYRNAINVGLPVIELKEVDEINQGDELEIDLENGVLKNLTTGKEYRFTPIPKFLLEILKEDGIVNYLKKHGSFPKV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit 1, Alpha-IPM isomerase 1, IPMI 1, Isopropylmalate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: ARFA_HAEIN
Sequence: MRKKQKSAVENETVYLHTRGVIKDNAVMALLGDKLFRQRVEKKRKGKGSYQRKAKHPGKIFEKPDYKFF
What is the function of this protein?
Rescues ribosomes stalled at the 3' end of non-stop mRNAs.  Recruits release factor 2 (RF2) to the stalled ribosome, helping position it correctly in the ribosomal A site so its GGQ motif can hydrolyze the peptidyl-tRNA bond (By similarity).
What are the official names of this protein?
Alternative ribosome-rescue factor A.
What is the protein family that this protein belongs to?
Belongs to the alternative ribosome-rescue factor A family.
Protein: RNP3_METBU
Sequence: MAERSFYDLSIHYVPDGKNTAEELISMAKHLGFAGIGLSNHSTAEGPLKSDGTEGFDIFRTVELVASNPSKLHGLVGKYRNKVDVLAVHGGDEGINRAAVENSNVDILIHPFTPKGSGLNHVLAKSASENNVAIAFDIDSLIMSRGGRRVHSLSHFRDYLALSRKYDVPMLLTSNALSIFGLRAPREIIALAALFGMEKDEAIMALSETPLKIVQKKRHDKNYVCEGVEIFEPSPSVLGDE
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_LEPBJ
Sequence: MADDKKSVKKEKKVKKKEKKIVPRGKVYITASFNNTIVTITDMAGNTISWSTSGAMGFRGSKKSTPYAAQIAAGNAAEKAMDSAGLQEVDVMVSGPGIGRESAIRSLVARGLNIKMIKDVTPLPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: XYNA_DICTH
Sequence: MINQRFSILVLLLILLTFSLGFLKEEAKGMEIPSLKEVYKDYFTIGAAVSHLNIYHYENLLKKHFNSLTPENQMKWEVIHPKPYVYDFGPADEIVDFAMKNGMKVRGHTLVWHNQTPGWVYAGTKDEILARLKEHIKEVVGHYKGKVYAWDVVNEALSDNPNEFLRRAPWYDICGEEVIEKAFIWAHEVDPDAKLFYNDYNLEDPIKREKAYKLVKKLKDKGVPIHGIGIQGHWTLAWPTPKMLEDSIKRFAELGVEVQVTEFDISIYYDRNENNNFKVPPEDRLERQAQLYKEAFEILRKYKGIVTGVTFWGVADDYTWLYFWPVRGREDYPLLFDKNHNPKKAFWEIVKF
What are the official names of this protein?
Beta-1,4-xylanase, 1,4-beta-D-xylan xylanohydrolase, Endo-1,4-beta-xylanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CTP5A_MOUSE
Sequence: MDSVPRLNSVLTLVLSGLWHLGLTATNYNCDDPLSNFLSLKAFSSSSDITGSSSSAQLNWRMGTGGWSPADSNAQQWLQIDLQNRVEITAVATQGRYGSSDWVTSYRLMFSDTGHNWQPYNQEDSIWTFVGNMNSDSVVHHKLLHSVRARFVRFVPLEWNPNGKIGMRVEAYGCSYRSDVADFDGRSSLLYRFNQKTMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALYLNLDDSKARLSSTVPLVILGSLLDDQHWHSVLLERVGKQANFTVDMNTQHFRTKGDTDSLDIDYELSFGGIPVPSKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYSGNVTFSCSEPQIVPITFINSRSSYLMLPGTPQIDGLSVSFQFRTWNEDGLLLSTELSEGSGTLLLILEGGTLRLLIKKVARHGTEILTGSGLNDGLWHSVSINARRNRVTLTLDNDAASPAPDTSRIQIYSGKSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGSFSDLHIDLCSIKDRCLPNYCEHGGHCDQTWTTFYCNCSGTGYTGATCHDSIYEQSCEVYRHRGHTAGFFYVDSDGSGPLGPLQVYCNITEDKIWMTVQHNNTELTRVQGSSPENPYSMTLNYGGSMEQLEALIDGSEYCEQEVIYHCRRSRLLNTPDGAPFTWWIGRSTERHPYWGGAVPGVQQCGCGLEESCLDSRHFCNCDADIDEWANDTGLFSFKDHLPVTQIIIMDTNRTNSEAAWRIGPLRCYGDRHFWNAVSFSTEASYLHFPTFHTEFSADISFFFKTTALSGVFLENLGIKDFFRLEMSSPSEVTFAIDVGNGPIELLVQSPYPLNDNQWHYIRAETNLKETSLQVDNLPQSMREASEGGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLLLNGHKVDLEERAKVTSGVRPGCPGHCSSYGSNCHNGGKCVEKHTGYSCDCTNSPYEGPFCRKEISALFDSGTSVTYMFQEPYPVTKNTSLSSSAIYTDLAPFKETIMLSFMTTQAPTLLLYLNFSSQNFLAILLSRNGSLQVRYRLSKDESHVFNMDTENLANRRVHQVKISRDGPELSIQMDQQLFSYSFSPEVEFRTLRSLVLGKVTETLDLDPEVARANTLGFVGCLSSVQYNHIAPLKAALRHASIAPVTVQKTLTESSCGSMVDSDVNAVTTVHSLSDSFGKTDDHEPLQNAVRSDSAVIGGVIAVVTFITFCVIGIMTRFLYQHKQSHRTNQMKKEYPENLDNSFRNEIDLQNTATECKREYFI
What is the function of this protein?
May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
What are the official names of this protein?
Contactin-associated protein like 5-1, Cell recognition molecule Caspr5-1, Cell recognition molecule Caspr5a, Contactin-associated protein-like 5a.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: FHR5_HUMAN
Sequence: MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSLQNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHSVCINGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFRAICQEGKFEYPICE
What is the function of this protein?
Involved in complement regulation.  The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH.
What are the official names of this protein?
Complement factor H-related protein 5, FHR-5.
What are the subcellular locations of this protein?
Secreted.
Protein: FTHS_STACT
Sequence: MTHLSDLDIANQATIKPISEIAEKIGIPEDALEQYGHYKAKIDINKLDDKGDRGKVVLVTAMSPTPAGEGKSTVTVGLADAFHELGENVMMALREPALGPVFGIKGGATGGGYAQVLPMEDINLHFNGDFHAITTANNALAAFIDNHIHQGNELGIDQRRIEWKRVLDMNDRELRKVVVGLGGPTQGVPREDGFNITVASEIMTILCLSTGLKDLKASIANITIGYTRDRKPVTVADLKVEGALAMILKDAIKPNLVQSIEGTPALIHGGPFANIAHGCNSIIATETARKLADIVVTEAGFGSDLGAEKFMNIKARKAGFEPSAAVVVATIRALKMHGGVAKDDLKEENVQAVRDGLANLERHIENIRSFGVEPVVALNAFVSDTEAEEQVVEDWAKEHGVRIALTEVWEKGGKGGVELAKQVQEVLNEKHDFKHTYDLDLPIEEKIEKVVTNIYGGNKVTFTSGALKQLKQIKENGWDNYPVCMAKTQYSFTDDKDRLGAPDDFEITIRELQPKTGAGFIVALTGAIMTMPGLPKKPAALNMDVTEDGHAKGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: CHR23_ARATH
Sequence: MVKQLQEQEENDPVEKTKSLISALNYLSRDLLLPSHLYASVSSIYHASVSDLSPSPPLRGNSYTPNRGDLMSEFEDALLQQRLNYESGSRLAELKETRYKNRIHNRLSQLEGLPSNRGEDLQEKCLLELYGLKLQELQCRVRGEVSAEYWLRLNCADPERQLYDWGMMRLPRRMYGVGDSFVMEADDQFRNKRDAERLLRLEEEEKNLIETTQRKFFAEVLNAVREFQLQIQASHRRCKQRNDGVQAWHGKQRQRATRAEKLRIMALKSDDQEEYMKLAKESKNEKLTLFLEETNKIFVSLGAAVQRQKDAKLSENTKLLKGSESDLSDVDAPEDVLPAQDIEIIDSDNNDDSNDLLEGERQFNLAIHSIQEKVTKQPSLLQGGELRSYQLEGLQWMVSLYNNDYNGILADEMGLGKTIQTIALIAYLLESKDLHGPHLILAPKAVLPNWENEFALWAPSISAFLYDGSKEKRTEIRARIAGGKFNVLITHYDLIMRDKAFLKKIDWNYMIVDEGHRLKNHECALAKTLGTGYRIKRRLLLTGTPIQNSLQELWSLLNFLLPHIFNSIHNFEEWFNTPFAECGSASLTDEEELLIINRLHHVIRPFLLRRKKSEVEKFLPGKTQVILKCDMSAWQKLYYKQVTDVGRVGLHSGNGKSKSLQNLTMQLRKCCNHPYLFVGADYNMCKKPEIVRASGKFELLDRLLPKLKKAGHRILLFSQMTRLIDLLEIYLSLNDYMYLRLDGSTKTDQRGILLKQFNEPDSPYFMFLLSTRAGGLGLNLQTADTIIIFDSDWNPQMDQQAEDRAHRIGQKKEVRVFVLVSIGSIEEVILERAKQKMGIDAKVIQAGLFNTTSTAQDRREMLEEIMSKGTSSLGEDVPSEREINRLAARTEEEFWMFEQMDEERRKKENYKTRLMEEKEVPEWAYTSETQEDKTNAKNHFGSLTGKRKRKEAVYSDSLSDLQWMKAMESEDEDASKVSQKRKRTDTKTRMSNGSKAEAVLSESDEEKEEEEEERKEESGKESEEENEKPLHSWKTNKKKRSRYPVMTSSPNSRGKGSSKGSKRN
What is the function of this protein?
Probable chromatin-remodeling factor that is functionally redundant with CHR12 in root and shoot stem cell initiation and root apical meristem (RAM) and shoot apical meristem (SAM) maintenance.  Can associate with the promoter region of WOX5 (PubMed:23062007).  May promote seed maturation and repress initiation of germination (PubMed:24839909).  May repress plant growth (PubMed:24666886).
What are the official names of this protein?
Probable ATP-dependent DNA helicase CHR23, Protein CHROMATIN REMODELING 23, AtCHR23, Protein MINUSCULE 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS192_ARATH
Sequence: MATGKTVKDVSPHDFVKAYASHLKRSGKIELPLWTDIVKTGRLKELAPYDPDWYYIRAASMARKIYLRGGLGVGAFRRIYGGSKRNGSRPPHFCKSSGGIARHILQQLETMSIVELDTKGGRRITSSGQRDLDQVAGRIAAES
What are the official names of this protein?
40S ribosomal protein S19-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: COBQ_ANOFW
Sequence: MRRALPIMFQGTHSDAGKSMLATAFCRIFARNGWKTAPFKSQNMSLNSYVTLDGKEIGRAQGVQAEAAGVVATTHMNPILIKPSRDQEAQIVVHGKPYENMKASTYRNEFFHLGLELIQQSLHVLMNEYDRLVIEGAGSPAEVNLNDRELVNMRVARMANAPVVLVGDIERGGVFASLVGTLQLLEEQDRKRVIGVIINKFRGDLSLLEPGLRWFEQYTGVKVLGVVPYMHVRIDAEDSVALSRYATKKDDAKAIDVAVIRYPRISNFTDIDPFFAEPDCSVRFVSDASSLGEPDILILPGSKNTIEDVYFLTETGLFSSIQRLYERTNVTMIGICGGYQMLGECIKDPFHVETPLDAVAGLSLLPIETTLACEKTTVLSEGTLVYKNEMFDVKGYEIHMGRSIVKQGEPLILLSGKTDGCKTKDERVIGTYMHDLFHNDMFRHHLLNGVRRKKQLSPLMERPNYRQLRAQAFDDLADCVEKHVDVKAIERKMIEFQRGEHHAL
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: NU2M_SYLOL
Sequence: MNPMTFTVLLATIMSGTSIVLLSSHWFMTWLGFEMNMMAIIPVLMKKYNPRSMEAATKYFLTQATASMILVLAIIINTMYSGQWTIMNMENQLASILITLALVMKLGLAPFHFWVPEVTQGVSLDSGLILLTWQKIAPLSLLYQIYPSLNTNLLLTMSLLSIMIGGWGGLNQTQLRKIMAYSSIAHMGWMIAIMTYNPNLSLLNLIIYITMTSSMFMLLIINSTTSTLSLSLTWNKTPIVTTMMLISLLSLGGLPPLTGFMPKWMIIQELTKNNSLILPTLMSILALLNLFFYMRLAYSTTLTMFPTTNNTKLSWQFKNTNILPTTAPLISISTMILPLTPLLITLN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FOLR1_HUMAN
Sequence: MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGPWAAWPFLLSLALMLLWLLS
What is the function of this protein?
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells (PubMed:23851396, PubMed:23934049, PubMed:2527252, PubMed:8033114, PubMed:8567728, PubMed:19074442).  Has high affinity for folate and folic acid analogs at neutral pH (PubMed:23851396, PubMed:23934049, PubMed:2527252, PubMed:8033114, PubMed:8567728).  Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release (PubMed:8567728).  Required for normal embryonic development and normal cell proliferation (By similarity).
What are the official names of this protein?
Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18.
What is the protein family that this protein belongs to?
Belongs to the folate receptor family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane; Lipid-anchor, GPI- anchor. Basolateral cell membrane; Lipid-anchor, GPI-like-anchor. Secreted. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Endosome. Note=Endocytosed into cytoplasmic vesicles and then recycled to the cell membrane.
Protein: PYRF_MYCMM
Sequence: MTGFGARLAEAKAHRGPLCLGIDPHPELLRAWDLPATADGLAAFCDICVAAFAGFAVVKPQVAFFEAYGAAGFAVLEGTMAALRANGVLVLADAKRGDIGSTMAAYAAAWAGDSPLAADAVTVSPFLGFGSLRPLLEVATANDRGVFVLAATSNPEGATIQRADADGRTVAQLIVDQVGLFNSEVGEVTGPEPGSVGVVVGATVLNPPDVSGLGGPVLVPGVGVQGGRPEALGGLGGAAPQQLLPAVSREVLRAGPSISEVRAAAERMLDSVAYLSAV
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: FENR_POLAQ
Sequence: MLHSPIEADAVIIGAGPVGLFQVFELGLLEIKAHVIDSLPEAGGQCIELYPDKPIYDIPAVPVCTGRELTQNLLKQIEPFGAQFHLGQEVRTLEQQADGRLLIGTSQNQYFLSKTVFIAAGVGAFQPRKLALEGIEALEDKHIFYHVKHPEQFSGKKIVICGGGDSALDWALFLVEKAASVTLIHRRDDFKAAPKSIAKMRELCASKQMQLLIGQITSYEAQDDHLKEIVVTDIDGKTQALPVDDLLIFFGLSPKLGPIAEWGLDIERKQLVVDTEKFQTSIPGIYAVGDINIYPGKKKLILSGFHEAALAAFAAAAYLNPEKQIQLQYTTTSPKLHKALGVGSPTFE
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: HNMT_HUMAN
Sequence: MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
What is the function of this protein?
Inactivates histamine by N-methylation.  Plays an important role in degrading histamine and in regulating the airway response to histamine.
What are the official names of this protein?
Histamine N-methyltransferase, HMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family.
Protein: DNLI1_METBF
Sequence: MERKEIKDSAYLFLGSIGPAFENITLGIGDKLALKAIAGAYRVSEEEVKKRYSRTGDLGDVAFELNQGEEKSLAIDEVFGSLKEIKEASGKGSQEEKTGLLSSILQRASPKEGKYIVRIVLGKLRLGFGDQFLLEAFSIAFTGDKKYVVKIKESYSVCTDIGELAESLAEQGPKALGHFSIKLGRPVRSMLAQRVKTFEELEERIPGKKAAEEKYDGERVQIHKNGEEIKAFSRRLEDITAQYPDVIEAVRKGILAKKIVLDGEIIAYVEGGKANDSTGEFYSFQRLMKRRRKYEVQKYTEICPVAVFFFDILYLEGNSLLKKPYPERRAILEEHVKESEILHLARRIVTDNLEEIEDFFNEALEKRLEGIIIKSMGRNSAYEAGKRSWFWLKWKEEYASGMRETFDLAIIGKYYGRGKRKGSFGALLCAILNGEEQRFETFTKVGTGFTEADAKEIDSLLSEHIISEVPKNVLIKSRMLPDIFVEPSLVIEVLGSEITESPSHTAGQGEGDTGLALRFPRFLRIRHDKGPYDITTLTEVRNLKEGKSI
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase 1, Polydeoxyribonucleotide synthase [ATP] 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: CX6A1_RAT
Sequence: MASAVLSASRVSGLLGRALPRVGRPMSSGAHGEEGSARIWKALTYFVALPGVGVSMLNVFLKSRHEEHERPEFVAYPHLRIRTKPFPWGDGNHTLFHNPHMNPLPTGYEDE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6A1, mitochondrial, Cytochrome c oxidase polypeptide VIa-liver.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DADX_PSEPK
Sequence: MRPARALIDLQALRHNYRLARELTGAKALAVIKADAYGHGAVRCALALEAEADGFAVACIEEALELRAAGIKAPVLLLEGFFEASELALIAEHDLWCVVHSLWQLEAIEKTPLHKPLNVWLKLDSGMHRVGLHPKDYHDAYQRLLASGKVSRIVLMTHFARADELDADATSQQIAVFEAARQGLAAECSLRNSPGVLGWPQAPSDWVRPGLMLYGATPFEVAQAEAARLQPVMTLQSRVISVRELPAGEPVGYGAKFVSPRPTRVGVVAMGYADGYPRQAPNGTPVLVAGKRTQLIGRVSMDMLSIDLTDVPQATVGSPVEFWGKQVLASEVAAHAGTIPYQIFCNLKRVPRDYIGE
What is the function of this protein?
Isomerizes L-alanine to D-alanine which is then likely oxidized to pyruvate by DadA.  Shows racemase activity with both alanine stereoisomers, negligible activity with D-cysteine and L-serine, and exhibits no activity with the remaining natural chiral amino acids.
What are the official names of this protein?
Alanine racemase, catabolic.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PETN_SYNE7
Sequence: MELLTFGWAALLAVFTFSLAMVVWGRNGDGSIGF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: YIDD_SHEB8
Sequence: MAQTQSPLQWLATTLIRGYQVFISPILGPRCRFNPTCSHYAIEAIKVHGTAKGCWFALKRILKCHPLHPGGSDPVPPKNDRCNK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.