PharMolix/UniProtQA huggingface dataset:
Protein: STIM1_HUMAN
Sequence: MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGSIGEETDSSPGRKKFPLKIFKKPLKK
What is the function of this protein?
Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:15866891, PubMed:16005298, PubMed:16208375, PubMed:16537481, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:18854159, PubMed:19249086, PubMed:22464749, PubMed:24069340, PubMed:24351972, PubMed:24591628, PubMed:26322679, PubMed:25326555, PubMed:28219928).  Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain.  Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375, PubMed:16537481).  Involved in enamel formation (PubMed:24621671).  Activated following interaction with STIMATE, leading to promote STIM1 conformational switch (PubMed:26322679).
What are the official names of this protein?
Stromal interaction molecule 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single- pass type I membrane protein. Cytoplasm, cytoskeleton. Sarcoplasmic reticulum. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane (PubMed:19249086, PubMed:16005298, PubMed:16208375, PubMed:18854159). Associated with the microtubule network at the growing distal tip of microtubules (PubMed:19632184). Colocalizes with ORAI1 at the cell membrane (PubMed:27185316). Colocalizes preferentially with CASQ1 at endoplasmic reticulum in response to a depletion of intracellular calcium (PubMed:27185316).
Protein: NAPA_BORPA
Sequence: MSMARRDFIKQTAAAAAATVAGVPLTGYTQNIVTESEAAKLKWSKAPCRFCGTGCGVNVAVKDNQVVATHGDFNAEVNKGLNCVKGYFLSKIMYGSDRLTQPLLRIKDGKYAKDGEFAPVSWDQAFDVMAEQFKRVLKDKGPEAVGMFGSGQWTVWEGYAALKLMKAGFRTNNLDPNARHCMASAAVGFMRTFGADEPMGCYDDIENADAFVLWGSNMAEMHPILWTRVTDRRLSAPATKVAVLSTFEHRSYELADLTLTFEPQSDLAILNYIANHIIRTKRVNRDFVDKHTVFREGNADIGYGLRPEHPLQQAARNAGDAGGSKPITFDDFARFVSKYDLEYTAKLSGVPKNRLEELAELYADPKVRVTSFWTMGFNQHTRGVWCNNMVYNIHLLTGKISTPGNSPFSLTGQPSACGTAREVGTFSHRLPADLVVTNPEHRRHAEEIWKLPDGTIPSKVGAHAVLQNRMLKDGKINAYWVMVNNNMQAAANLMNEGLPGYRNPENFIVVSDAYPTVTTLSADLILPAAMWVEKEGAYGNAERRTQFWHQLVDAPGQARSDLWQLVEFSKRFKVEEVWPADLLAKKPEYRGKTLYDVLFANGKVNQFPNTELDPEYANQEAQAFGFYLQKGLFEEYAEFGRGHGHDLAPFDVYHKARGLRWPVVDGKETLWRYREGSDPYVKPGTGFQFYGNPDGKAVIFALPYEPPPEAPDKEYPFWLSTGRVLEHWHSGSMTRRVPELYKAFPEAVCFMHPDDAQALGVRRGVEVEVVSRRGKMRTRVETRGRDKPPRGLVFVPWFDAGQLINKVTLDATDPISFQTDFKKCAVKIVKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PHT2_ORYSJ
Sequence: MATVEVLTSEVVAPAEETPAGAVWLSNLDLAARRGYTPTVYFYRRNGDDEAAFFAADAVRDGLARALVPFYPLAGRLGLAGGGEDGRVQIDCTGEGAVFVTARSGHYALDDLMNEFVPCDEMRDLFVPPTPPPNPPCALLLVQVTHLRCGGVVLGMALHHSVVDARSAAHFAETWASIVRGAPAGDAPVPPCFDHKLLAARPARAVLYDHPEYKPEPAPAPAHAATASTYASAIITLTKQQVGALKAACAGASTFRAVVALVWQCACRARSLPPDKANLFLLYKYISEDWVDIQLNIQQRDNCIYAPTLKANCCFTPTF
What is the function of this protein?
Hydroxycinnamoyl transferase that catalyzes the transfer of an acyl from p-coumaryol-CoA to putrescine, to produce coumaroyl putrescine.
What are the official names of this protein?
Putrescine hydroxycinnamoyltransferase 2, OsPHT2.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: IPPK_HUMAN
Sequence: MEEGKMDENEWGYHGEGNKSLVVAHAQRCVVLRFLKFPPNRKKTSEEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQLCLKIQSERPESRCDKDLDTLSGYAMCLPNLTRLQTYRFAEHRPILCVEIKPKCGFIPFSSDVTHEMKHKVCRYCMHQHLKVATGKWKQISKYCPLDLYSGNKQRMHFALKSLLQEAQNNLKIFKNGELIYGCKDARSPVADWSELAHHLKPFFFPSNGLASGPHCTRAVIRELVHVITRVLLSGSDKGRAGTLSPGLGPQGPRVCEASPFSRSLRCQGKNTPERSGLPKGCLLYKTLQVQMLDLLDIEGLYPLYNRVERYLEEFPEERKTLQIDGPYDEAFYQKLLDLSTEDDGTVAFALTKVQQYRVAMTAKDCSIMIALSPCLQDASSDQRPVVPSSRSRFAFSVSVLDLDLKPYESIPHQYKLDGKIVNYYSKTVRAKDNAVMSTRFKESEDCTLVLHKV
What is the function of this protein?
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).  InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation.  It also protects cells from TNF-alpha-induced apoptosis.
What are the official names of this protein?
Inositol-pentakisphosphate 2-kinase, IPK1 homolog, Inositol-1,3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase, InsP5 2-kinase.
What is the protein family that this protein belongs to?
Belongs to the IPK1 type 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS13_CHRVO
Sequence: MARIAGVNIPNHAHAVIGLQAIFGVGQTRAQQICAAASVNPSTKVKDLTEAEMEALRDQVAKFTVEGDLRREITMSIKRLMDMGCYRGFRHRRGLPCRGQRTRTNARTRKGPRKAIAGKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RH6_ARATH
Sequence: MNNNNNNRGRFPPGIGAAGPGPDPNFQSRNPNPPQPQQYLQSRTPFPQQPQPQPPQYLQSQSDAQQYVQRGYPQQIQQQQQLQQQQQQQQQQQEQQWSRRAQLPGDPSYIDEVEKTVQSEAISDSNNEDWKATLKLPPRDNRYQTEDVTATKGNEFEDYFLKRDLLRGIYEKGFEKPSPIQEESIPIALTGSDILARAKNGTGKTGAFCIPTLEKIDPENNVIQAVILVPTRELALQTSQVCKELSKYLKIEVMVTTGGTSLRDDIMRLYQPVHLLVGTPGRILDLAKKGVCVLKDCAMLVMDEADKLLSVEFQPSIEELIQFLPESRQILMFSATFPVTVKSFKDRYLKKPYIINLMDQLTLMGVTQYYAFVEERQKVHCLNTLFSKLQINQSIIFCNSVNRVELLAKKITELGYSCFYIHAKMVQDHRNRVFHDFRNGACRNLVCTDLFTRGIDIQAVNVVINFDFPRTSESYLHRVGRSGRFGHLGLAVNLVTYEDRFKMYQTEQELGTEIKPIPSLIDKAIYCQ
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: SPI5_SOLTU
Sequence: MKCLFLLCLCLVPIVVFSSTFTSQNPINLPSDATPVLDVTGKELDPRLSYRIISIGRGALGGDVYLGKSPNSDAPCANGVFRFNSDVGPSGTPVRFIGSSSHFGPHIFEGELLNIQFDISTVKLCVSYTIWKVGDYDASLGTMLLETGGTIGQADSSWFKIVKSSQLGYNLLYCPFSSDDQFCLKVGVVHQNGKRRLALVKDNPLDVSFKQVQ
What is the function of this protein?
Inhibitor of trypsin (serine protease).  Protects the plant by inhibiting proteases of invading organisms (By similarity).
What are the official names of this protein?
Serine protease inhibitor 5, gCDI-B1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Vacuole.
Protein: DFG5_YEAST
Sequence: MIVNISAKMILSICFTFLSFFKATHAMDLDTTSKTSICDATALIQGGMLDYYEGTRYGGTVGMFQSPYYWWHAGEAFGGMLENWFLCENDTYQELLYDALLAQTGSNYDYIPSNQTMVEGNDDQGIWGITVMGAVERNFTDPGDGKPGWLAMVQAVFNTMYSRWDSEHCGGGLRWQIFTWNSGYNYKNTVSNACLFQIAARLGRYTGNTTYLEVAEQVFDWLVDVGYVVLNDTANVFDGAEIDTNCTDITKIEWTYNHGIVLGGLAYMYNATNGTGEWETSLTKILNGAKSYFFKDSIMYESACQDYGTCNTDQRTFKSIFSRMLGLTSVMAPFTRDTIDDLIKTSAEAAAKSCNGGTDGHTCGLNWQKQTNDGYYGLGEQMSALEVIQNLLIHDRPAPYKEDNGGTSKGDANAGMNSSTTNVLQNNLNIKKGDRAGAAIITAVILSVLTGGAVWMLF
What is the function of this protein?
Required for normal synthesis of the cell wall.
What are the official names of this protein?
Mannan endo-1,6-alpha-mannosidase DFG5, Endo-alpha-1->6-D-mannanase DFG5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 76 family.
Protein: ATPH_IPOPU
Sequence: MDPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CVP6_PIMHY
Sequence: MSRYALIVLIVVVVAANLCEASDCGPNRVYKSCGTGCPETCENPDPDCDRACHQGCFCSKGLLQDIDGNCISPDKCP
What is the function of this protein?
May be a phenoloxidase inhibitor that stabilizes or inhibits venom phenoloxidase while it is stored in the venom sac.
What are the official names of this protein?
Cysteine-rich venom protein 6, cvp6.
What is the protein family that this protein belongs to?
Belongs to the serine protease inhibitor-like (TIL domain-containing) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLYA_ACIC1
Sequence: MNSSPDPLAALTATDPTIADLIRAEERRQSEKIRLIPSENYVSKAVLEATGTVLTNKYSEGYPNRRYYEGQQFIDQIETIAIERAKQLFGVDHANVQPYSGSPANLAIYLALLSPGDTVMGMALPMGGHLTHGWPVSATGIWFRSVQYGVRRDTGRIDFDEVREVARRERPKVIFAGGTAIPRIIDFAAFAEIAREVNAVLVADIAHISGLVAGGVHPSPVGHADIISTTTHKTLRGPRGAMLMSTEQYAKALDKAVFPGLQGGPHNHTTAAIAVALLEAMQPEFRDYARNIVANAAVLAEELLARGFDLVSGGTDNHLILVDLTSKGVAGKPVARALDRAGIELNYNTVPFDPRKPFDPSGIRLGTPAVTSRGMGPAEMRQIAAWIDEVTTAVAKGDEEALAAVEQRVAGEVRELTKNFPTPGLDR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRF_PASMU
Sequence: MEITLGIAMFTVIVLALAVIILFAKSKLVNSGDITIEINDDPSKAIHLPAGGKLLGALASQGIFVSSACGGGGSCGQCIVKVTEGGGDILPTELSHISKREAKEGYRLSCQVNVKNSMKVELPEEVFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFRAGGYIQIEAEPHTVAYKDFDIPEEYHEDWDKYNLWRYVSKVDEHIIRAYSMASYPEEKGIIMLNVRIATPPPNNPDAPPGQMSSYIWSLKAGDKVTISGPFGEFFAKETDAEMVFVGGGAGMAPMRSHIFDQLKRLKSKRKMSFWYGARSKREMFYVEDFDTLQAENDNFVWHVALSDPQPGDNWDGYTGFIHNVLYENYLKDHEAPEDCEYYMCGPPIMNASVIKMLKDLGVEDENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BIOC_LARHH
Sequence: MTEAFYTDKSRVRASFDRAAATYDRAAVLQREVCDRMATRLDLIRHAPARVLDAGSGTGYGAGLLRARYPEAQVTELDLAPSMLRASRDKQLPQGRLRRLFARAPALVCADLEQLPLASGSLDMVWSSLALQWLNTPDAVLAEFHRVLRVDGLLMFATLGPDTLKELRQAFAGIDGATHVNQFIDMHDMGDALVRAGFATPVMDVERIVLTYDEVKAVMRDLKAIGAHNATAGRGRGLMGRQAWQRIEAAYDRLRQDGRLPATYEVVYGHAWRPAARPRRKLDDGRDIIEFHPHAPA
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: LITD1_HUMAN
Sequence: MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEFRDYVLHMPTLRELLGNNIP
What are the official names of this protein?
LINE-1 type transposase domain-containing protein 1, ES cell-associated protein 11.
What is the protein family that this protein belongs to?
Belongs to the transposase 22 family.
Protein: RHLB_VIBCM
Sequence: MKKTHITEHKFADFGLQPQVIDGLEKKGFVYCTPIQALALPVLLSGQDIAGQAQTGTGKTLAFLTATFNHLLTTPAAEGRAETQPRAIIMAPTRELAIQIFNDAEPLLASTGLKAALAYGGESYDKQLAKLQSGVDILIGTTGRIIDFYKQRVFNLNHIQAVVLDEADRMFDLGFIKDIRFLFRRMPEPKDRLNMLFSATLSYRVQELAFEHMNNPEHVVVEPEQKTGHRIQEELFYPSNEHKMALLQTLIEEEWPDRAIIFANTKHRCEQIWAHLAADNHRVGLLTGDVPQKKRERILEQFTQGDVDILVATDVAARGLHIPQVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISFACEEYAINLPAIESYIEHAIPTSDYDPSALLTDLPAPLSLRSSPQQRRTNTAGSRNSNNGGNRKPQQRRPRAPRPKKEA
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_ROSDO
Sequence: MSNAELETAIEAAWEARDSISPATKGAERDAIEATLAALDGGGLRVAERQADGNWHVNQWAKKAVLLGFRIKDMEMQSGGAQGGGWWDKVDSKFAGWGEADWKDAGFRAVPNCVVRKSAYIAPGVVLMPSFVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGKSTKIVDRETGEFTYGEVPAGSVVVAGSMPSKNGVNLYCAVIVKKVDAQTRSKTSINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDH3_SHV2C
Sequence: MIPSNKFVTNNPGSPGGPGGPGGPGGPGGPGGPGGPGGPGGPCGPGGPCGPGGPCGPGGPGGPGGPRSPVSSIGYLRFGSLAIFFKTVCVALVSCFLCYSIFF
What are the official names of this protein?
Uncharacterized 9.5 kDa protein in DHFR 3'region, ORF3.
Protein: HRCA_XANCP
Sequence: MRASQSPMLDPRARHLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDIGLLSSPHTSAGRVPTAHGYRVFVDSLVQMQPPGEEEVRRLRAELASSNGTQSLLGSASQMLSAMSHFVGVVSAPRREQFAFRHIDFVPLDARRVLAILVFADNEVQNRVIEPRRAYEPAELERVANYLNAQFAGRALSDIRASLLRELRLAKNEMEQLLAHSVDLASEALVPADDDGMVMAGQTRLMGVQDLSDLDRLRELFEAFASKREILQLLERTIQAPGVRIFIGEETGMVSLDDVSLVTAPYTAGGQVLGVLGVIGPKRMAYDRVIPLVQTAAQMLGAAMEPPGTR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: URE3_MYCTA
Sequence: MRLTPHEQERLLLSYAAELARRRRARGLRLNHPEAIAVIADHILEGARDGRTVAELMASGREVLGRDDVMEGVPEMLAEVQVEATFPDGTKLVTVHQPIA
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCA_ECO27
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: FLOA_STAA3
Sequence: MFSLSFIVIAVIIVVALLILFSFVPIGLWISALAAGVHVGIGTLVGMRLRRVSPRKVIAPLIKAHKAGLALTTNQLESHYLAGGNVDRVVDANIAAQRADIDLPFERAAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIARLVGGAGEETIIARVGEGIVSTIGSSKHHTEVLENPDNISKTVLSKGLDSGTAFEILSIDIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVATEQEMKARVQEMHAKVVEAESEVPLAMAEALRSGNISVKDYYNLKNIEADTGMRNAINKRTDQSDDESPEH
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: RS2_METHJ
Sequence: MNGNEMEIELNEPLVSVEEYLAAGVHIGTQQKSSDMKNFIYRVRGDGLYILDIRETDERIKLAAKFLSQYDPAKILVVTSRQYGQYPARRFADSIGATPIIGRYIPGTLTNPLLPRYAEPDVVVVTDPVSDLQVIREAIQVSIPVVALCDTNNMTSLVDVVVPTNNKGRKALSMIYFLLTKEFLRHKGYNTSLTPEDFETEM
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ZA2G_BOVIN
Sequence: MVPVLLALLLLLGPAVSEETQAGNYSLSFLYTGLSKPREGFPSFQAVAYLNDQPFFHYNSEGRRAEPLAPWSQVEGMEDWEKESALQRAREDIFMETLSDIMDYYKDREGSHTFQGAFGCELRNNESSGAFWGYAYDGQDFIKFDKEIPAWVPLDPAAQNTKRKWEAEAVYVQRAKAYLEEECPGMLRRYLPYSRTHLDRQESPSVSVTGHAAPGHKRTLKCLAYDFYPRSIGLHWTRAGDAQEAESGGDVLPSGNGTYQSWVVVGVPPEDQAPYSCHVEHRSLTRPLTVPWDPRQQAE
What is the function of this protein?
Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers.
What are the official names of this protein?
Zinc-alpha-2-glycoprotein, Zn-alpha-2-GP, Zn-alpha-2-glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Secreted.
Protein: NQOR_ECODH
Sequence: MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: ANMK_ZYMMO
Sequence: MLAIGLMSGTSLDGVDVALIETNGEKQVKPLNFASYPYSDTDKACLREACRRALTMAAPCFIPEDEVIYQAEHIVTLRHIQAVKDFLKKNALGNQAIKVIGFHGQTIAHRPDLGWTWQIGDGAALAQATKISVVDDFRSHDVQAGGEGAPLLPIYHWALFSEASHPLAVLNLGGIANITWIGADENDLIACDTGPANGMIDDWVKAKTGLDYDESGLIASKGVVHHDLVDAMMSQKFFSQLPPKSLDRSDFSIEAVANLSIEDGAATLTAFTAESVARSLSFFPERPSKIIVAGGGRHNVTMMKMLHDSLKMPVQPIEDFHLNGDATEAEGFAYLAVRRVFNKPISFPKTTGVPHPMTGGRIHYI
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ARGB_STAA8
Sequence: MKFIVIKIGGSTLSDMHPSIINNIKHLRSNNIYPIIVHGGGPFINEALSNQQIEPHFVNGLRVTDKATMTITKHTLIADVNTALVAQFNQHQCSAIGLCGLDAQLFEITSFDQQYGYVGVPTALNKDALQYLCTKFVPIINSIGFNNHDGEFYNINADTLAYFIASSLKAPIYVLSNIAGVLINDVVIPQLPLVDIHQYIEHGDIYGGMIPKVLDAKNAIENGCPKVIIASGNKPNIIESIYNNDFVGTTILNS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOOK3_HUMAN
Sequence: MFSVESLERAELCESLLTWIQTFNVDAPCQTVEDLTNGVVMAQVLQKIDPAYFDENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEILGQQINDFTLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQERDRLFHSLEKEYEKTKSQREMEEKYIVSAWYNMGMTLHKKAAEDRLASTGSGQSFLARQRQATSSRRSYPGHVQPATAR
What is the function of this protein?
(Microbial infection) May serve as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking.
What are the official names of this protein?
Protein Hook homolog 3, h-hook3, hHK3.
What is the protein family that this protein belongs to?
Belongs to the hook family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Golgi apparatus. Note=Enriched at the cis-face of the Golgi complex. Localizes to microtubule asters in prophase (PubMed:11238449). Localizes to the manchette in elongating spermatids (By similarity).