PharMolix/UniProtQA huggingface dataset:
Protein: RSEC_ECOLI
Sequence: MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFASDVAALCGAILGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSSEDASQ
What is the function of this protein?
May play a role in reduction of the SoxR iron-sulfur cluster.  May work together with the RsxABCDGE complex.
What are the official names of this protein?
Protein RseC.
What is the protein family that this protein belongs to?
Belongs to the RseC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Z_WWAVU
Sequence: MGLRYSKDVKDRYGDREPEGRIPITLNMPQSLYGRYNCKSCWFANKGLLKCSNHYLCLKCLTLMLRRSDYCGICGEVLPKKLVFENSPSAPPYEA
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.  Also selectively represses protein production by associating with host eIF4E.
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells.
Protein: RBCR_CYACA
Sequence: MTDLPFTLDQLRILRAILIQGSFKKAATSLYISQPAVSSHVHNIEKQLNIQLFDRSHRNAQLTEAGQLLLKYGGRILALCEETCRALEDLQNLQCGNLIIGASQTTGTYLMPKLIGLFRQKYPQISVQLQVHSTRRISWSVANGQLDLAIIGGEVPKELTEILEVRNFVEDELTLILPPSHPFSKFSCIQKEDLYRLRFIALDKNSTIRKVIDKILNRNGIDSSRLKTEMELSSIEAIKNAVQSGLGASFVSISAIDKELKLQLLNRVNIDKIKIKRMLSIITNYSRYRSKASETFCHEILGLLVNLPFKNAPSTEK
What is the function of this protein?
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
What are the official names of this protein?
Probable RuBisCO transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DOA1_YEAST
Sequence: MGYQLSATLKGHDQDVRDVVAVDDSKVASVSRDGTVRLWSKDDQWLGTVVYTGQGFLNSVCYDSEKELLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNVCSLSFQDGVVISGSWDKTAKVWKEGSLVYNLQAHNASVWDAKVVSFSENKFLTASADKTIKLWQNDKVIKTFSGIHNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGDVLRTYEGHESFVYCIKLLPNGDIVSCGEDRTVRIWSKENGSLKQVITLPAISIWSVDCMSNGDIIVGSSDNLVRIFSQEKSRWASEDEINELSTQVEKSTISSKTIEFDESKLSPYEILQSPGRKEGQIVVVKSPQGTIEAHQFSNSSWKKVGDVVGAGATGNDKKIEFEGKTYDYVFDVDIEDGKPPLKLPINVSDNPYTAADNFLARYELPMSYRDQVVQFILKNTNGISLDQPNDNASSSAVSPSKTSVMKVLPVKQYLIMENYNPDTIFNGIVKINSNEKTFDDEILAQIGGALHDIDESWELLLSFANTIRSNWEIKTPAYDIVRLIVKKLPYSSDIKDYIEEGLGNKNITLTMLTVRILVNCFNNENWGVKLLESNQVYKSIFETIDTEFSQASAKQSQNLAIAVSTLIFNYSALVTKGNSDLELLPIVADAINTKYGPLEEYQECEEAAYRLTVAYGNLATVEPTLRQFANSVTWLANIKRSYGNVPRFKDIFDDLS
What is the function of this protein?
Ubiquitin-binding protein involved in protein ubiquitination, sorting and degradation (PubMed:2111732, PubMed:8890162, PubMed:19805280, PubMed:18508771, PubMed:20508643, PubMed:27044889).  Acts as a ubiquitinated substrate-recruiting adapter for chaperone ATPase CDC48 by binding mono- or polyubiquitin chains (PubMed:15096053, PubMed:16427015, PubMed:16428438, PubMed:27044889).  Depending on the context, promotes or prevents proteasomal degradation of ubiquitinated proteins (PubMed:2111732, PubMed:8890162, PubMed:19805280, PubMed:27044889).  Involved in the ubiquitin fusion degradation (UFD) pathway by promoting the degradation of ubiquitinated proteins (PubMed:2111732, PubMed:8890162, PubMed:19805280, PubMed:27044889).  Involved in the mitochondria-associated degradation pathway (MAD) by promoting the degradation of several ubiquitinated membrane proteins (PubMed:27044889).  By competing with UFD2 to bind CDC48, prevents the multi-ubiquitination and subsequent degradation of UFD2-dependent substrates (PubMed:16427015).  Required for ribophagy, a process which relocalizes ribosomal particles into the vacuole for degradation in response to starvation (PubMed:20508643).  Involved in the ubiquitin-mediated sorting of membrane proteins into multivesicular bodies (MVBs) (PubMed:18508771).  In addition, plays an essential role in maintaining cellular ubiquitin levels (PubMed:7615550, PubMed:16427015, PubMed:16428438, PubMed:18508771, PubMed:19805280).  May affect indirectly the degradation of ubiquitinylated proteins by regulating cellular ubiquitin levels (PubMed:7615550, PubMed:23525333).
What are the official names of this protein?
Protein DOA1, Degradation of alpha protein 1, Ubiquitin fusion degradation protein 3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PLAP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Predominantly localizes to the cytoplasm. Probably localizes to endosomes and mitochondria in a transient manner.
Protein: Y2662_VIBCM
Sequence: MKLTHSFIKQQARLGLNFFRYLLARMNHDRVNVNAGYLAYITLLSMVPMLTVLLSILSSFALFANAGEVIQDFVITHFVPAAGEVVKTALIEFVANTGKMTAVGGAFLFVAAIMLISNIDKNLNYIWRVQQKRRAVFSFSMYWMILTLGPILVGASIAATSYITSLKILDNEALSGVYNLFLRWLPFVLSYCAFVGLYLLVPNKKVHWQHAMLGALIAAILFELSKKGFAAYITQFPSYQLIYGALAAIPILFVWVYLCWLIVLVGAEVTAALGEREHWSDSQDMLHFAPLPKNEKE
What are the official names of this protein?
UPF0761 membrane protein VCM66_2662.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL4_SPIKU
Sequence: MKLQVLDANGTSVKEISVNDAIWGIEPHQQAMFDAVIAQQASMRQGTHKTKTKTEVSGGGRKPWRQKGTGRARQGSIRAPQWKGGGIVFGPTPEKKYLKHVNKKVRKLAIKSAFSLKVQDKNIMIIDQFGIDKPSTKAMVKVLNNLKVNGEKLLIITTEGDEVNFKSSRNIEKVNIITSAGINIYDLLNANKLLVTEQAIKAIEEVYS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: KATIP_XENLA
Sequence: MHGKSLGSSRKNDSRSKIRQEKESNIDFDEKHDEYLINLQQRNRALNNSKAKDATQIKLQHLEEGFSLYLNGANADLRKQQSTQDLARESSKSSKIPDDGCSHLPGRRSQTAPGKIQRKAWVQNSIQIKSERGSRVYIGPNTKYSEDFESDDDMNEDQASDQYKYFTDSEKNVPQGPGKKRLVLDASDVKALRESLEISLCLQQDSKYSLDDDDADFVEEELIECETPELDSPSKTQLESKHQAFGHQRLLPGDFVVLEFNALDKKDGRMLTAKRKDNSEFYIPTKPVMVKNKTPRLKSSSFSSKDSFFPRPESRQEILLPTPRRSISENKDSRPSVSTVVDAINNENEAITRAISDGKTEKMTSGPSGISEGVVTKAIEKINLMKISQQKKLLKVLQDIDNDSSTNSNSEGEILKWDSVYLDPAVKDVICITVEILSNWGNQYYIGLTEIQFFDLKNEEIYVSPHDVDIRNVDVPGDPTCLVNGKTLTTKEHFMWTCPFHPPVQLYFIIRNATKSGDFDISKMKIWNYNKALSDLDIGAKLVKIYKDETLVFDGLLAKGSGNQDFDYSNTIDLHSGQIKSSSFISDQFSDETQISNSLGASNNIELKHQSDGLVYTSEQLSSILSEGSNQAKTSQQKDLHFENNTKGLRTFQDEALNKSFQHLALTSSSINCQEDITEGEVGIKMSYNKEEHFKINQSKDFNTMTAELQMVSATSSKEPPPCPRDDNDLTVTDQLERTPGRKECSSLNRFPPWLSSSSNFQQKSHNQPTKNHLNASSSTFTNKRSDQDINQFLDEYVKSSNTYSNKNFKNCSQSKMLCSSSKMDNEDDLENFSNQSSYNSDRPVSGRRKTVQMQDKSEKYEGASFHKTINPVDTKNLRPRWQNDQENNLLESWTSLIKFNKSHRGRISNLEFEGDIFDEFLQQQQKAGKQSDSTKNGSSLMPKGATEIHLESEKEEGSNFEIPVLPYGQHLCIKIVTTWGDRHYVGLNGIEVFASTGKPVEISRIRADPPDINILPAYGKDPRVVVNLIDGVNRTQDDMHLWLAPFSPGKLHFINLDFVEPCRVAMIRIWNYNKSRIHSFRGVKEVEIFLDNELIFKGEIAKASGTLSGAAEQFGDTILFTTDDEILQAMSLFDETFSEELKATETPTEHEIDSLRPSTADSIKEERPFTQAGLSEKLQSNLTDVSENYSDKLPGIYSGKCLLLNFTMTWGDPHYLGLTGMEIVGRDGKALAITLDALSACPQDLSILPEYKDDLRTLDKLIDGVNITNEDTHMWLIPFASGADHTITINFNKSEDIAGIRFWNYNKSPEDTYRGAKIVYVTLDGHAISPPGGFLIRKGPGNCHFDFAQEILFVDYIHEQQILEKQLRSHSKCMELATMDYEAPLMPCGFIFQLQLITSWGDPYYIGLNGLEM
What is the function of this protein?
May control cilium integrity.
What are the official names of this protein?
Protein KATNIP homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton. Note=When overexpressed, localizes to the cytoplasm where it associates with acetylated alpha-tubulin.
Protein: SPCS2_MACFA
Sequence: MAAAATQGGRSGGLGGNSGAGGGSNCGTGSGRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLAVERKIK
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 2, Microsomal signal peptidase 25 kDa subunit, SPase 25 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NFCP_CONGI
Sequence: MAGLLKESMRIKIYMEGTVNGYHFKCEGEGDGNPFEGTQNMRIRVTEGAPLPFAFDILSPCCAYGSKTFIKHTSGIPDYFKQSFPEGFTWERTTIYEDGGVLTAHQDTSLEGNCLIYKVKVLGTNFPADGPVMKKISGGWEPCTEIVYQDNGVLRGRNVMALKVSGRPPLICHLHSTYRSKKACALTMPGFHFADLRIQMPKKKKDEYFELYEASVARYSDVPEKAT
What is the function of this protein?
Non-fluorescent pigment protein that is mauve in color.  The wild-type form is non-fluorescent.
What are the official names of this protein?
GFP-like non-fluorescent chromoprotein, cgCP, cpCP.
What is the protein family that this protein belongs to?
Belongs to the GFP family.
Protein: CLPX_GLUDA
Sequence: MNNKSSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVKSRDGVPTPKEICKVLDDYVIGQFYAKKVLSVAVHNHYKRLAHSQKNNDVEIAKSNILLVGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNMLFICGGAFAGLDKIISARGKGSGIGFGADVQSPDERRTGAILRDVEPEDLLKFGLIPEFIGRLPVVATLEDLDEAALIEILTKPKNALVKQYARLFQMEGVKLTFTDDALKQVALRAIARRTGARGLRAIMESILLSTMFDLPGLENVDEVVINKDVAESKTSPVYVYGKEKPAEQSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SPLC_STAAS
Sequence: MNKNIVIKSMAALAILTSATGINAAVVEETQQIANAEKNVTQVKDTNIFPYNGVVSFKDATGFVIGKNTIITNKHVSKDYKVGDRITAHPDGDKGNGGIYKIKSISDYPGDEDISVMNIEEQAVERGPKGFNFNENVQALNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDNILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
What are the official names of this protein?
Serine protease SplC.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: NORW_ECOL5
Sequence: MSNGIVIIGSGFAARQLVKNIRKQDASIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDKLVLATGASAFVPPVPGRELILTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILATLDRQRCIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLRWHIYTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLSM
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_HELPY
Sequence: MIDRKLLLQDFDKVALSLKKRNNAMDDELERLREVITHYKKRLIELEGLQAFQNKVSKEFGIKMAQKVDTSDLKKELENNKIKLNELSKSVGELEQQIDLKLSIIPNLVDEKTPLGTNEEDNIEIKKILTPRVFTFKPKEHFELAQQNGWIDFESGVKLAKSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLYNDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDVMQEHMLESASEILKALELPHRFVQLCSGDLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQADGSIHIPKALEKYL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_CLOB6
Sequence: MARISGIDLPKEKRVEIGLTYIYGIGLPTSQEILKATGVNPDTRVKDLSEEEVNAIRDYVNKNVKVEGDLRREIKLNIKRLVEIGSYRGIRHRRNLPVRGQKTKTNARTRKGPKRAIGGKKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL27A_TETTH
Sequence: MVSHLKKTRKLRGHVSHGHGRVGKHRKGGCRGGRGKAGGMHHHRILMEKWHPGYYGKLGMRTFHLKKNPLHCPVVNIDKLWSLVSDATRQKYAEDKKKVPVIDVTKAGFFKVLGKGRLPNQPVVVKAKYFSKTAERRIVAVGGACVLTA
What are the official names of this protein?
60S ribosomal protein L27a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ENV_MLVFR
Sequence: AAPGSSPHQVYNITWEVTNGDRETVWAISGNHPLWTWWPVLTPDLCMLALHGPPHWGLEYQAPYSSPPGPPCCSGSGGSSPGCSRDCNEPLTSLTPRCNTAWNRLKLDQVTHKSSEGFYVCPGSHRPREAKSCGGPDSFYCASWGCETTGRAYWKPSSSWDYITVDNNLTTNQAVQVCKDNKWCNPLAIQFTNAGRQVTSWITGHYWGLRLYVSGQDPGLTFGIRLKYQNLGPRVPIGPNPVLADQLSFPLPNPLPKPAKSPPVSNSTPTMISPSPTPTQPPPAGTGDRLLNLVQGAYQALNLTNPDKTQECWLCLVSGPPYYEGVAVLGTYSNHTSAPTNCSVASQHKLTLSEVTGRGLCIGTVPKTHQALCNTTLKTNKGSYYLVAPAGTTWACNTGLTPCLSATVLNRTTDYCVLVELWPRVTYHPPSYVYSQFEKSYRHKR
What is the function of this protein?
The surface protein (SU) attaches the virus to the host cell by binding to its receptor.  This interaction triggers the refolding of the transmembrane protein (TM) and is thought to activate its fusogenic potential by unmasking its fusion peptide.  Fusion occurs at the host cell plasma membrane (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM.
Protein: MATK_ANEMR
Sequence: MTEAFSAIHELGGIRGIGGIRGIRRSSYWQQKFLYLFLFQDHFYGIVYNSFVNESEYVRNTTIHGLTYGFNFVMLKHLMKKLHQSQSPSILFDELTNQSQFVREILMIASNPILQPRSRDSAGRINEWNGYQSIHSVFPFIEDRIHNPSNYLDITIPHCVHPEILIRICRKHILDISFLHLLRLMLHTSNHFRIPNSSNRVINLFYRFLWNFCTQSIEYCLIHLWKQIYKFQCTPFWFLFDKTEFIRKIQSVSKKSNPRPDRTISRKNCLIHYVRSQNHLILVIDGEGDFESIKDWKILFIILWSKYLHSWLDPCRISVKNLSNNPLSILGYILYTKNDLIKIRIRFFDFSINTSLVIKGFCGIIPIISLIRSLAKEGFCNTSGRPICKLSWTTLTDNEIIYRFDRIMRNIFYYYSGCCKKKGLYQLQYIFRFSCAKTLACRHKSTIRTVWKRYGSNFARNYVVLEGVKSIPSNLWQRESDEKRFWCLTITQTNFLADLLRKSKNIYSVG
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: TRM1_BHV2B
Sequence: MADAFDPSDTRPDELAAVARQKLLVVLGQLQTYIFQVELLKRCDPQVARHQIGKLKLNALQVRAVSRHFMEGMSSQAATLITPLTLALELSLEYARREGEKLLEALNDLGERSSPVAYFEGTMGLARGCPHHQAVKLATYGGEIDKELCFLHDVENFLKQMNYCHLITPASAAAEALVSVKAFLARTVGSELIVPPEISDPSHPCHVCFEELCVTANQGATASRRLAGKICDHVTQQARVRLDADEMRRNLPHVVGLSEARRARALHALEVSSKMTEANSGGPAEAPGPAAAQEREASALLDAHHVFKSAPPGLYAVSELRFWLSSGDRTSGSTVDAFADNLSALAERERRYETGAVAVELAAFGRRGEHFDRTFGDRVASLDMVDALFVGGQSAAPDDQIEALVRACYNHHLSAPVLRQLAGSEHGDAEALRSALEGLHAAEDPPGDGNAEKEARRAPSLGGGPEDDWAALAARAAADVGARRRLYADRLTKRSLASLGRCVREQRGELEKMLRVSTYGEVLPTVFAAVCNGFAARTRFCELTARAGTVIDNRGNPDTFDTHRFMRASLMRHRVDPALLPGITHQFFELVNGPLFDHATHGFAQPPNTALYFSVENVGLLPHLKEELARFMMGKADSDWAISEFQKFYHFDGTSGITPTQRIA
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: PGS1_HORSE
Sequence: MPTMWPLWLLASLLALSQALPFEQKGFWDFTLDDGLPMLNDEEASGADTTSGIPDLDSLTPTFSAMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNEISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFQPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK
What is the function of this protein?
May be involved in collagen fiber assembly.
What are the official names of this protein?
Biglycan, Bone/cartilage proteoglycan I, PG-S1.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HFA2D_ORYSJ
Sequence: MEKMMPGMVKEEWPPSSPEEGEAPRPMEGLHEVGPPPFLTKTFDLVADPATDGVVSWGRAGSSFVVWDPHVFAAVFLPRFFKHNNFSSFVRQLNTYGFRKIDPDRWEFANDGFLRGQRHLLKMIKRRRPLSYLPGSQQALGTCLEVGQFGLDEEIDRLKRDKNILLAEVVKLRHKQQSTKANMRAMEERLQHAEQKQVQMMGFLARAMQNPDFFHQLIHQQDKMKGLEDTFSKKRTRSIDIVPFLNPGEVSQGDQLESTLLFDPRPFAELNDEPAKSELENLALNIQGLGKGKQDVNRTRNQPRNQASNETELTDDFWEELLNEGARDDAGIPGMERRRPRYVDALAQKLGYLSNSSQK
What is the function of this protein?
Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor A-2d, Heat stress transcription factor 7, rHsf7, Heat stress transcription factor 8, OsHsf-08.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NPW_PIG
Sequence: MGARGPGPGATARRRLLALLLLLLLLPLPARAWYKHTASPRYHTVGRAAGLLMGLRRSPYMWRRALRPAAGPLAWDTFGQDVPPRGPSARNALSPGPAPRDAPLLPPGVQTLWQVRRGSFRSGIPVSAPRSPRARGSEPQPELGASSWTSAE
What is the function of this protein?
Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland.  Stimulates water drinking and food intake.  May play a role in the hypothalamic response to stress (By similarity).
What are the official names of this protein?
Neuropeptide W, Preproprotein L8, PPL8.
What is the protein family that this protein belongs to?
Belongs to the neuropeptide B/W family.
What are the subcellular locations of this protein?
Secreted.
Protein: HFLD_ECO8A
Sequence: MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSIIDMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL
What is the function of this protein?
Negative regulator of phage lambda lysogenization.  Contributes to the degradation of the phage regulatory protein CII.  Acts probably by holding CII on the membrane surface, away from the target promoters, but close to the FtsH protease.
What are the official names of this protein?
High frequency lysogenization protein HflD.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARCA_CUTAK
Sequence: MTTPIGAWSEVGKLREVMVCEPRLAHRRLTPSNCRELLFDDVLWVEKAQEDHRDFVAKMRERGIVVHEMHQLLSEVLDISEGRSWVLDRKLSPNAVGLGVDEDVRDWLNDMPSDTLAEYLIGGVAYGEVPADRRKHVLGALIKAHSENEFLIPPLPNTQFTRDTTAWIFGGVTFNPMRWPARQQETVLASAIYTHHPIFAERDFKIWYGCAEADHGMSTLEGGDIMPVGNGTVLIGMGERSSWQAITQVARSLFAQNAARRMVVAAMAPDRASMHLDTVFSFCDVDLVTLYKPVVDTITPLVLEPSSEAAGFSVRVDDRHFTDVVASSLGLDGLRTVETGGDCWEAQREQWDDGNNVVALEPGVVVGYDRNTATNALLAKAGVEVVEIKAAELGRGRGGGHCMTCPITRDPVDY
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y701_POLAQ
Sequence: MMKGGLAGLMKQAQQMQEKMKTAQAELAALEVNGQAAGGLVKVAISGKYELKRVQIDPGAMDDREMLEDLIVTAYTEAFKQVEAASTQLMSGATAGMPMPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Pnuc_0701.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ARGE_ECO27
Sequence: MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASCGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYDAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHKLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.