PharMolix/UniProtQA huggingface dataset:
Protein: ATIF_CYBJA
Sequence: TAGATGATRQDGSTDAFEKREKAQEDLYIRQHEKEQLEALKESLKKQKKSLDDLEBKIDDLTK
What is the function of this protein?
This protein forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
What are the official names of this protein?
ATPase inhibitor, mitochondrial, ATP synthase F1 subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the ATPase inhibitor family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SCX29_CENNO
Sequence: LCLSCRGGDYDCRVKGTCENGKCVCGS
What are the official names of this protein?
Peptide Cn29.
What are the subcellular locations of this protein?
Secreted.
Protein: EDRF1_HUMAN
Sequence: MGDAKEAGAEGPPAGAAARGGLSLLSQGESEESSAQGSALFLGGNEVKSRAVVKYSSAPPRTAFARLEEKTDLKLPPANWLRESAKLGPAGTTILGNSKKSKPFSSFGMAYDFIDSVGNDVDVVSDSENIKKLLKIPYSKSHVSMAVHRIGRTLLLDELDIQELFMRSSQTGDWTWLKEFYQRLIDQKWQRKKKSKEHWYQKAILSKFLYYSINGDGAAQPVSSTAEQQESSSSDQTNDSEGASWPAPFEMPSSVSEDPSASSQGSEPLEPSYIVGHVASAPKEQNLITLFNDGEHSQGLKNDFVRNILWTFEDIHMLVGSNMPIFGGGRYPAVSLRLRDNNKPINVLTGIDYWLDNLICNVPELVMCFHVNGIVQKYEMIKTEEIPNLENSNFSTKVIKDIAQNILSFLKSNCTKEGHTYWLFKASGSDIVKLYDLTTLCEETEDKYQNPFTMPVAILLYKVACNMMMKKNQNKKHYGTIRTLLLNCLKLLDKSRHPQIIASANYMLSELFQLDEPKKEENSESPLNENSDESYSEEEEEMPDSDENGSYSTSSDPSDDSKAVAIIKSVGELSVPEKYKSIHQIRPSCAFPVCHDTEERCRLVLSYVLEGLKSVDSSIKKESDLPAADPSTPIPLKYEDESSRGGPEGLEKQMALFLDKMGSLQKGNYSSQSGMIPGSWQHKMKLQLILKSSKAYYVLSDAAMSLQKYGRALRYIKLALQSHDTYCCLCTNMLSEVLLFLSQYLTLCGDIQLMLAQNANNRAAHLEEFHYQTKEDQEILHSLHRESSCQGFAWATDLSTDLESQLSVSCKCYEAANEILQFSDLKSQNPEHYVQVLKRMGNIRNEIGVFYMNQAAALQSERLVSKSVSAAEQQLWKKSFSCFEKGIHNFESIEDATNAALLLCNTGRLMRICAQAHCGAGDELKREFSPEEGLYYNKAIDYYLKALRSLGTRDIHPAVWDSVNWELSTTYFTMATLQQDYAPLSRKAQEQIEKEVSEAMMKSLKYCDVDSVSARQPLCQYRAATIHHRLASMYHSCLRNQVGDEHLRKQHRVLADLHYSKAAKLFQLLKDAPCELLRVQLERVAFAEFQMTSQNSNVGKLKTLSGALDIMVRTEHAFQLIQKELIEEFGQPKSGDAAAAADASPSLNREEVMKLLSIFESRLSFLLLQSIKLLSSTKKKTSNNIEDDTILKTNKHIYSQLLRATANKTATLLERINVIVHLLGQLAAGSAASSNAVQ
What is the function of this protein?
Transcription factor involved in erythroid differentiation.  Involved in transcriptional activation of the globin gene.
What are the official names of this protein?
Erythroid differentiation-related factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: VIP1_BOVIN
Sequence: MWSLPASEGESATAHFFLGAGDEGLGTRGLGMRPEESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVIILGEDVILNEPVENWPSCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPMEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFSLFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASNEGQDTQREALAPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYNQLAPTGSTSLLSSMAVIQNPVKVCDQVFDLIENLTHQIRERMQDPKSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDTQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEEGSAPTGCGFRPASSENEERKADQGSVEDLCPGKASDEPDRALQTSPLPSEGPGLPKRSPLIRNRKAGSMEVLSETSSSRPGGHRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARSQGKKLPPASLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTEAQAQASAALFDSMHSNQASDSPFSPPRTLHSPTLQLQQRSEKPPWYSSGPSSTVSSAGPSSPTAVDGNCPFGFSDQPSVSSHVTEEYQGLGLLQEAPGSGAQEPPLEGQQEPFEQNQSPQEPPVETKKPCQEVAEEVSQPCQDIPEEVNQPCQQVSDICQPCEENHDDVDQTCQEVPQISQPCEDASQLYQKVSKEVCELCQNSEEVNQPCQGVPVEIGRLVHGFPVGVGGLAQEVLGEVGRPTQEIPEELSQSCQEFSVDIGRLAQEASAINLLSPDTPEVDNPPLEFPGEGALQAQEVSEWVKQQQSYVVPELIDQLSREEVPQVQCPPSNANPQSQSLAPDQNAPLPPATCDSSFSH
What is the function of this protein?
Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4.  PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation.  Phosphorylates inositol hexakisphosphate (InsP6) at position 1 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4.  Alternatively, phosphorylates PP-InsP5 at position 1, produced by IP6Ks from InsP6, to produce (PP)2-InsP4.  Activated when cells are exposed to hyperosmotic stress.
What are the official names of this protein?
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1, Diphosphoinositol pentakisphosphate kinase 1, Histidine acid phosphatase domain-containing protein 2A, InsP6 and PP-IP5 kinase 1.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Note=Relocalizes to the plasma membrane upon activation of the PtdIns 3-kinase pathway.
Protein: CH10_NITMU
Sequence: MQIRPLHDRVIVKRLEEERKTASGIVIPDSAAEKPDQGEIIAVGKGKVGDDGNVRPLEVKVGDKVLFGKYSGQTVKISGEELLVMREEDIMGVVEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHBA_PHOLL
Sequence: MQHNKIKVAFLDRDGVINKEVNYLHKIEDFEYTSKCIVGLKKIRDLGYEIIIITNQAGIARGYYSEKQYQLLTDWYRNDLKEKGVDILDIFHCPHYPDGIVPELSKDCYCRKPSPGMIEQARKKYSIDIKSSILVGDKNSDIHAGERAGIPRCFLVKTGHPTSEPTENAILSNNLFTISKLIE
What is the function of this protein?
Converts the D-glycero-alpha-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the GmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_CLAM3
Sequence: MPRSLKKGPFVDDHLLRKVISANEASSKNVIKTWSRRSMIIPAMLGHTIAVHDGRKHVPVFVTESMVGHKLGEFALTRTFRGHVKDDKKGRRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NU1C_PROM0
Sequence: MEYGLDLEYSFNEFLKGFGLSSEIAHIIWLPLPMLLVLVAAVVGVLVTVWLERKISAAAQQRIGPEYAGALGVLQPIADGLKLLVKEDIIPAKADGILFTAGPILVLVPVILSWLIVPFGQNLLISNVGIGIFLWIALSSIQPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLALSVLAIVLMTNSLSTIDIVNQQSGAGILSWNIWRQPVGFIVFWICALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYLGSYINLILSALLVSILYLGGWGFPIPVELIAKFLNLPINAPLIQVFTASIGIVMTVLKAYLLVFIAILLRWTTPRVRIDQLLDLGWKFLLPISLANLLITAGLKLAFPQFFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: NPL21_CAEEL
Sequence: MKPENGAATWHPAKRSCLGRLTTLETLLLVFLGLLITALLSVLFLWLWVLDGYKTFTDGRPIYPLPFENSSVAVDRSAKNHNDVVCTSRECVRLAGFLAENLNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNKQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKWGAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEKEMNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVFPFINFEKYLKTVFKELVALSPNHTVIVREIDYFVGIQHVLQSTPKRVLANYISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPREYLLHLTIRVKLVRFTEELLRLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW
What is the function of this protein?
Probable cell surface protease.
What are the official names of this protein?
Neprilysin-21.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: SYE_DEIGD
Sequence: MSVVTRIAPSPTGDPHVGTAYIGLFNHTLAQQARARGEEGKFILRIEDTDRNRYVPDSERRIFQMMAWLGLTPDESPLQGGPNGPYRQSERTAIYGEYARKLVEAGHAYYAFETPEELAALREAAQQEGRVIAVPSRDLDPAEAQRRVDAGESAVIRLKVPREGETVVNDALRKPIAFQNREIDDKVLLKADGYPTYHLANVVDDHLMGVTHVIRAEEWITSTPIHVLLYRAFGWAEPIFAHMPLLRNADKSKISKRKNPTSVEWYMAQGFLPEAMLNFLATMGWTHPEGKEIFDLAEFQRVFRLEDVTLGGPVFSLDKLRWMNGKYLREVLSEEEVAERLHAYLASQKHDLPDDDYFRAVVRMMIPRMDVFSEFLEKTPYFWSEDYPVSEKAQHLIEEGRPFLPELAARLKNLPSFDPATTEAALRAFAEERGLKPGKVMQPLRAAIAGTSESPGMFELLEVLGQERVVARVERAARGG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_STAA9
Sequence: MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMVNTELDRMVSEFAQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CARB_HYPBU
Sequence: MPRRIDVRKVLMLGSGAIKIAEAAEFDYSGSQALKALREEGIETVLVNPNVATIQTSYKLADHVYLGPLQPWFVEKVIERERPDAILLGFGGQTALSLGVELHRRGILSRYGIRVLGTPIEGIEKALSRGKFRETMMKAGLPVPPSTPATSVEEALRAANEIGYPVIVRVSFNLGGGGSLVAWSREELERWLVRAFAFSGTGEVLVEKYLHYWKEIEYEVVRDQYGNMVAVACLENADPMGVHTGESVVIAPCQTLTDQEYQLLREASLRVAEAIGLVGEGNVQLALNPRDSWEYYVIETNPRMSRSSALASKATGYPLAYIAAKLALGYRLDELLNRVTERTCACFEPSLDYVVVKVPRWDLEKFEGVEKSIGSEMKSIGEVMAIGRNFAEALQKAIRMLDIGEPGVVAGPRYEEPESLEEVLGKLRRREPYWPIWAAKAFRLGASVEQVYEATGVDPYFLSQIREIVEVAEKLRRTKPWSSEFLDLLAEAKRLGFSDEQVALLTGTTVEKVEKARRSIGLDRPRVRQIDTLAAEWPAATNYLYMSYNAYEDDEPITTGRPRLIVLGAGVFRIGVSVEFDWGVVSFADEARRLGYEVVIVNYNPETVSTDWDISDKLYFEELTLERVIDIYWFEKPVGVIAFLGGQIANNLAKPLEERGVRLLGTPGRSVDRAENRAWFSQLLEELGIKQPSWTAASSIEEVLKFAESVGYPVLVRPSYVLSGSAMKIAWSPEELKSYIEQAARVSPRYPVVVSKFLEDAVEAEIDAVGDSRRTVGTVIEHVEPGGVHSGDSTMVIPWFSLPETAVREMIRIAETLNEVLEIKGPFNIQFLVKDGSVYVVELNLRASRSMPFTSKVTGYNLMRAAAEAALRGRISYGFNGADGFKLLRPTGWWGVKSPQPSWQRLRGAYPGLGPEMRSTGEVAALGRTLHEALLKSWLSVQGNRIPPAGSIVLIYTPTGRGSSDLSQAAKLMTEKGYTVYTIEGMEVDGAEPLPLEQALRLVRMGGVGLLMTTDYAPQRDYRVRRLAVDLGVPVVLDARLARMLAEAINRVGLENLEALELREYWGPNVEPF
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: DER_HELP2
Sequence: MNTSPKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGHEVELLDTGGMAKDALLSKEIKALNLKAAQMSDLILYVVDGKSIPSDEDIKLFREVFKINPNCFLVINKIDNDKEKERAYAFSSFGTPKSFNISVSHNRGISALIDAVLNALNLNQIIEQDLDADILESLETPNNALEETKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDETILIGDQKICFVDTAGIRHRGKILGIEKYALERTQKALEKSHIALLVLDVSTPFVELDEKISSLADKHSLGIILILNKWDIRYAPYEEIMATLKRKFRFLEYAPVITTSCLKARHIDEIKHKIIEVYECFSKRIPTSLLNSVISQATQKHPLPSDGGKLVKVYYATQFATKPPQISLIMNRPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYI_YERPE
Sequence: MSDYKNTLNLPETGFPMRGDLAKREPDMLKRWYEQDLYGIIRAAKKGKKTFILHDGPPYANGNIHIGHSVNKILKDIIVKSKGMAGYDSPYIPGWDCHGLPIELKVEQLIGKPGEKVSAAEFRTACRKYAAEQVEGQKKDFIRLGVLGDWDHPYLTMDFKTEANIIRALSKIIDNGHLHKGAKPVHWCTDCGSSLAEAEVEYYDKTSQSIDVRFNAVDTATVAAKFGVSAVNGPISLVIWTTTPWTLPANRAISLNAEYLYQLVQVEGECLILAADLVESVMKRAGITQWAVLGSCTGSDLELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDFVIGQKYGLEVANPVGPNGCYLAGTYPTLDGLFVFKANDVVVELLREKGALLHVEKLLHSYPCCWRHKTPIIFRATPQWFISMDQKGLRKQSLQEIKGVQWIPDWGQARIETMVANRPDWCISRQRTWGVPMSLFVHKETEQLHPRSIELMEEVAKRVEQDGIQAWWDLDPAEILGADAADYVKVPDTLDVWFDSGSTHSSVVDVRPEFGGHSPDMYLEGSDQHRGWFMSSLMIATAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTISPQDVMNKLGGDILRLWVASTDYTGEIAVSDEILKRSADSYRRIRNTARFLLANLNGFDPAQHQVKPEEMVVVDRWAVGRAQAAQAEIMEAYENYDFHLVVQRLMQFCSVEMGSFYLDIIKDRQYTAKGDGIARRSCQTALFHIAEALVRWMAPIMSFTADEIWNHLPGERQQYVFTEEWYDGLFGLAGNESMNDTFWAELLKVRGEVNKVLEQARSDKRIGGSLEAAVTLYAEPELAARLNSLQDELRFVLLTSAAKVAAYADAGNDAQQSELIAGLKITFNKADGEKCPRCWHYTQDVGLVAEHAELCGRCVTNVAGDGEERKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1450_METJA
Sequence: MYDFAIIGSGVAGATLAKELRYRYKVAVIEKGKKPSYASEGKNVEINYVYGLGGSGVYSLGNAIKTEIKGYKIDKDIYKEIWEELKIKAPKDDFLNDIDKAFIELGFEKMEKFIDFDRCNKCGECARKICKAKWTPLNYLKESNANIITEFNIKAINYSNYYEILDDKGRKIKAKNLIISAGGINSPRILKKMIDDENIGKNLFIDTFVTVGGILEDSYLNKDISMLVYKKYKNFMLATHYSKLLINEIKKDYKDVKEKDIVGIMIKIKDENNGVVLDNDVKKEITKEDFKTLARGICKATKYLYKLGVDDIYTTIPRGSHPGGSLSLVVDEFEVREGLYVCDASLFKEALGVPPIVSIIALSKKFVREIL
What are the official names of this protein?
Uncharacterized protein MJ1450.
Protein: SKP1_ORYSJ
Sequence: MAAEGEKKMITLKSSDGEEFEVEEAVAMESQTIRHMIEDDCADNGIPLPNVNSKILSKVIEYCNKHVHAAAAAASKAADDAASAAAAVPPPSGEDLKNWDADFVKVDQATLFDLILAANYLNIKGLLDLTCQTVADMIKGKTPEEIRKTFNIKNDFTPEEEEEIRRENQWAFE
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, a RING-box and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
What are the official names of this protein?
SKP1-like protein 1, SKP1-like 1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y677_TREPA
Sequence: MQYSGPMQEEVSERTCLVSDPSLSSVAGAGSGVVQAYVARQLARQVHACVDCGMRGIRRAVRRFAADVIAREAPELTAAKREALLDAWVPSPSSEHVAVGSQPAQACGGAPLPADVQYSMVLHFVWYGLGVLSEQERVQLEQAVPHWPQVYWSCFSPQLKRLIKACLTGLLDVEAFCAAVRTLLGIAGMDTAADASIHPHEK
What are the official names of this protein?
Uncharacterized protein TP_0677.
Protein: ELT1_CAEEL
Sequence: MDYEGKPVEFTLGTSSGGASLAPTSSTTAASIAPFSYNTSATNYYNTTPSSYPMFLNYQYAGGTTVTTDMDAFSGMDMSMNNGVFGTQNNPSYFYPTTQLNTYGYDTLAAATTASGITVNNNQLNVNIVQGNGTIVPQPITQNIISTVSNVQSSVPINNSQPLTPTGLAGCSTSSGSSSASSSSANSTSTPKNTISKANRSSGGANNSQFSTEDRECVNCGVHNTPLWRRDGSGNYLCNACGLYFKMNHHARPLVKPKKRQQNAQKRTGIECVNCRTNTTTLWRRNGEGHPVCNACGLYFKLHKVERPITMKKDGIQTRNRKLSAKGSRRMKKENGGTPTSMGMPTTSSSISSGIELDQSGVWGMKNTQPMLMTPTAYAFPASNFYFNSIEDQLEYKTCPPMMVDFGGQMKNLNLN
What is the function of this protein?
Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof (PubMed:19591818, PubMed:21829390).  During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage (PubMed:9224715, PubMed:16303852, PubMed:11259601).  The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres (PubMed:9224715).  Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion (PubMed:16303852).  Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif (PubMed:21829390).  Probably represses expression of eff-1 to prevent fusion of seam cells with the hypodermal syncytium (PubMed:21829390).  Involved in regulating expression of elt-3, a probable downstream target in hypodermal development pathways, in dorsal and ventral hypodermal cells (PubMed:16303852, PubMed:11259601).  During postembryonic development, has a role in sperm development (PubMed:19591818, PubMed:29702639).  Specifically, binds the bipartite consensus sequence 5'-AGATCTx(8)GATAA-3' found in genes with sperm-specific expression (PubMed:19591818).  Furthermore, regulates timing of developmental steps, possibly in parallel with daf-12, by controlling the expression of the let-7 family of miRNAs which in turn determines the transcription of heterochronic genes such as lin-41 (PubMed:25816370).
What are the official names of this protein?
Transcription factor elt-1.
What are the subcellular locations of this protein?
Nucleus. Perikaryon. Cell projection, axon. Note=Expressed in pachytene nuclei during the first stage of meiosis.
Protein: RSMH_CORDI
Sequence: MTHGEPQEFSFDVEENHGHVPVLRARMAELIAPKVTAMGSDAVIIDGTLGAGGHSKYFLESFPEARVIGLDRDTNSLASARERLKEFGDRFLGIHTRFDRFAPKLEELAQSGNPIAATALEQGISGALFDLGVSSMQLDQAERGFAYRVDAPLDMRMDNTIGITAADVLNTYSHGELARILKTYGDERFAGKIASAIVREREKEPFDTSARLVELLYATIPAATRRTGGHPAKRTFQALRIEVNRELESLENVLPEITQRLTTGGRAVFMSYQSLEDKIVKRYFVDISTSKTPPGLPMELPEYAPKFKVVTRGAEKATDAEIEENPRAASVRVRAIEAL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMP47_PASMU
Sequence: MAKTSKFTQTLLASALAVVAGSASAAAFQLAEVSTSGLGRAYAGEAAIADNAAVVATNPALMSLLKQPEISVGAIYVDPNINLTSPMPGFAYKNIAPNALVPTVYGVYPINEKFAVGGGLNVNYGLATEFDDKYAGGFLGGKTDLTAINFNLSGAYRVTEKFSVGLGLNAVHAKAKLERYAGVALKLKVPNVAQLAALPANTVISKLQGDKWGFGWNAGLVYEFNERNRIGIAYHSQVDINFKGQYSNHFPLAAAALLQTKGITATGGKEIPGTLHLPLPAYWEISGYHKMTDRFAMHYSYKYTQWSKFKELRAKGTDGKTLFSKTEEFRDSSRIALGASYDVTDALTVRTGIAYDESAADEHNTISIPDTDRTWFSVGATYRFTPNVSIDAGFAHLKGKKNTFKEEGVPFTSKASANLYGLNVNYRF
What are the official names of this protein?
47 kDa outer membrane protein.
What is the protein family that this protein belongs to?
Belongs to the OmpP1/FadL family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: PROB_PSEPW
Sequence: MRSKVTGAKRWVVKIGSALLTADGKGLDRGAMAVWVEQMVALREAGVELVLVSSGAVAAGMSQLGWTARPSAMNELQAAASIGQMRLVQAWESSFGEHGKHTAQILLTHDDLSDRKRYLNARSTLRTLVDLGVVPVINENDTVVTDEIRFGDNDTLAALVANLVEADLLVILTDRDGMFDADPRNNPEAQLIYEARADDPSLDAVAGGTGGALGRGGMQTKLRAARLAARSGAHTIIIGGRIERVLDRLKAGERLGTLLSPERGMLAARKQWLAGHLQTRGTLVLDAGAVQALRQANKSLLPVGVKTVQGSFRRGEMVVCVGPDGLEVARGLANYSALEAQKIIGQSSDAIESLLGYSAEPELVHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYTL3_MOUSE
Sequence: MAHEVDLESFKELERDIILRVLYRDQTVQSTEEERVRKLKSHLQHLRWKGAKSSSQEYKEKCCARCQRALGLLLNRGAVCQGCSHRVCSECRVFLRRTRAWKCTVCFEDRNVKIKTGEWFFEERARKFPTAGRRETAGAKLLQSYQRLSKISVVPPTPPPFSESQCSSSSRLQELGHFRGFNKSVENLFLSVTTQMRKLSKSQNDMTSEKHLLAMDPRQCVGHTERRSQSDTAVNVTSRKASTPDILKAFHQEDPKHPPDPVLKQDTPPSSPTHSAVFSGGLRHGSLISINSTCTEMGNFDNANVTGEIEFAIHYCVKSCSLEICIKTCKNLAYGEEKKRKCNPYVKTYLLPDRSSQGKRKTRVQKNTLDPTFEETLKYQVDPGQLMTRRLQVSVWHLGTLARRVFLGEVILPLAMWDFKDSTAQNARWYPLRAKAEKYEENIPQNNGELAVRAKLVLPAGPRKPQEAQEGQLALNGQLCLVVLGAKNLPVRSDGTLNSFVKGCLTLPNQQKLRVKSPVLKKQACPQWKHSFVFNGVSSSQLRQSTLELTVWDQAIFGMNDRLLGEARLGSKGGAAGCPDSGSQSKLQWHRVLSSPNLWTDMTLVLH
What is the function of this protein?
May act as Rab effector protein and play a role in vesicle trafficking.  Binds phospholipids in the presence of calcium ions.
What are the official names of this protein?
Synaptotagmin-like protein 3, Exophilin-6.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein.
Protein: TLP5_PHONI
Sequence: QKKDKKDRF
What are the official names of this protein?
Tachykinin-like peptide-V, P.nigriventer tachykinin peptides V, PnTkP-V, U29-ctenitoxin-Pn1e, U29-CNTX-Pn1e.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_AQUAE
Sequence: MRSDGRKEDQLRPVSIQRDFLEYPEGSCLISFGKTKVICTASVIENVPNWLKGKGQGWITAEYSMLPRATQQRTIRESVQGRIGGRTHEIQRMIGRAMRTAVELTKIGERTIWVDCDVIQADGGTRTAAITGAFVAVADAIIKLHKEGIIEETPIKDFVAAVSVGIVNDRILLDLNFEEDSAAQVDMNVVGTGSGRLSEVHTMGEEYSFTKDELIKMLDLAQKGINELIELQKKLYVIQDGKWERSELKEVSSTT
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.