PharMolix/UniProtQA huggingface dataset:
Protein: LGT_RHOJR
Sequence: MTSTVDVLAYIPSPPQGVWYVGPVALRAYALFIIVGIVVAIVWGDRRWVARGGEKGTVLDIAIWAVPFGLIGGRLYHVMTDWPTYFGEGGDPVDALKVWQGGLGIWGAVALGGVGAWIGCRRRGIPLPALGDAVAPAILLAQAIGRLGNYFNQELYGRETEVPWGLEIFERRNDVGQVSPQLIDGVSTGEVAFVVHPTFLYEALWNVLIVLLLVWVDRRFRIGHGRLFALYVAGYCAGRFWIELMRSDHASLIAGVRVNSFTSALVFVAALVYFFAATKGREDPAELRPADGGPVGGGGEPVDGEIAQKEPEKNVEDAGKDEGTSASEPVSDDKAASTASTGGEAGTKTIDSKKDDAND
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSB1_YEAS1
Sequence: MSNATNNTLGSLLPQLEAAANSNSLYGGMVPNLRFNITMIVIWGILLTIHVVQLLMRQYWFSIAFICTGILEVLGFIGRTWSHSNVADMDAFLLNMICLTIAPVFTMGGIYYQLAKLIEVYGHRFSLLPSPMAYSFIFICSDIVSLVVQAVGGGLCGVAVTDGTSTTTGNHVFIAGLAIQVASMAIFLMLWFHFLFRIYISVRWEHINSRPISLSLLKISQTEVDYLYREKFHFLRLEPKRWVFHYFNLAMTVAVLTIFTRCCYRLAELVVGWDGYLITHEWYFIILDALMMAIATVTLTIFHPGFAFKGRSTSIPITPGHVDPETLPHTDDVEDILDTSDSKQFDIEKEEFQASMKYPISTFKQFMSKIANLFSSKKKAKL
What is the function of this protein?
Catalyzes the ATP-dependent translocation of sphingoid long-chain bases (LCBs) from the cytoplasmic site toward the extracytoplasmic side of the membrane (flip-flop).  Involved in the establishment of the functional lipid asymmetry of the plasma membrane.  Regulates intracellular levels of LCBs, sphingolipid precursors that are growth inhibitory at increased levels (By similarity).
What are the official names of this protein?
Sphingoid long-chain base transporter RSB1.
What is the protein family that this protein belongs to?
Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBL_CARTI
Sequence: MSPQTETKTSVGFKAGVKDYKLTYYTPDYKTKDTDILAAFRVTPQPGVPPEEAGXXVAAESSTGTWTTVWTDGLTSLDRYKGRCYGIEPVPGEETQFIAYVAYPLDLFEEXXVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPXHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFIFCAEAIYKAQAETGEIKGHYLNATAGTCEDMMKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLATEGNEIIREATKWSPELAAACEVWKEIKFEFEAMDTLDV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YS25_CAEEL
Sequence: MVLEIVFFTSCLILSVVGVYLNLCYLRATHRSTVYPKFTGNNLRFLSVAHIVLACSNVVAAAAMWGANVNRTTKSEAFFSTTLSVSRAIPALTVFWTTVERITYNRSPTIRESPKFRYVAVFRVIEVVVSVIMEMIIRGIYLNSDDQLKEAAGLEVLQSSNDEISIKSSLIANVYYDFYHGILFLPCIIISVLMFKSAKGSHTRACLLGGMRNDQKIQNLSGQMTFFKNSYIMLYIACLADFILHVIVKRFINLEDSTLDMMYINARCFLPIVYPLSLIANNKNLRIDYFGNFILCRKARNLHKESKVKVIATRESQESIIANLKMIGILSDVDTSQGGAGAASLAMMGMGGGGAPRPPSGGRMASISKDPNSITSSGSLAKQSTASMGSGGASGMMMFHTRPKSSVPSMGSVG
What are the official names of this protein?
Uncharacterized protein ZK1320.5.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RF2_THERP
Sequence: MAQPMLIDLEELVERLDRIGVRLCLPSKRQQIEQLEHEAADPDLWQDPQRAQSLLRRLSQLRDLVQEWETLSQQARDLLELRALASDDLELAGQVEQEATELAERVRQLELRLLLTGQYDGHDAILAVHAGTGGVDAQDWAEMLLRMYLRWAQRAGFAAEVVDLLEGEEAGIKSATVEVRGPYAYGYLKGEAGTHRLVRLSPFDAAHRRHTSFALVEVLPLVEEDDDVEIREEDIRIDTFRASGHGGQHVNKTESAVRITHLPTGIVVTCQNERSQIQNRETAMKILKARLLELKIRQRQEEQARLKGKPVVTGWGNRIRSYVLHPYTMVTDHRTEVSTPNIQAVLEGEIDPFIEAYLHQQAAEGEETAAASDR
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_STRTR
Sequence: MAKKTKKTEEITKKFGDERWKALDDALKNIGKDFGKGAVMRLGERAEEKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQTQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIACKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGIMFGNPETTPGGRALKFYAYVALDVRGNTQIKGTGDKKDQNVGKETKIKVVKNKVAPPFKEAFVEIMYGEGISQTGELVKIASDIGIIQKAGAWFSYNGEKIGQGSENAKKYLADHPEIFAEIDHKVRVHYGLIELDEDDVVEDTQVEDTSDELILDLDSTIEIEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_BUCAI
Sequence: MHIIKTIKVLYKEIKILKKSNKKIGLVPTMGNLHDGHIKLILLAKKYSDIIIVSIFINPMQFDNLSDLKNYPKTFMKDSIILKKYHVDILFFPHINEIYPNGIEHQTFVEVIKLSKILEGQSRPGHFRGVTTIITKLFNFIQPDFAFFGEKDYQQLLIIKILVKELNYMIKIISLPTIRLKNGLALSSRNNYLSSQENEIAPYLYKIIKKTCEKIIKEDDNIRPKIIHESKILLIKKGFSVDIFDIYDYKNLEHPSKKVKKVILLASVWLGNTRLIDNKKIILNY
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_BLOFL
Sequence: MSAFTQHTGIALPLNITNIDTDNIIPKQFLKITSRSNLGKYLFFNWRYLENTPHTPNINFVLNNPYYQNASILITRKNFGCGSSREHAVWALIDYGFRVIIASSFANIFYKNSFNNRLLLVTLSESEIHSIFQNIHIHTHNNNKLFITVNLCENTVSIKNKKYFFKIKDSYRNYMLNNLDKISLTLKFESNIQKHENNQPLFLK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RANSP_LEPVA
Sequence: LLEGFLVGGGVPGPGTACLTKALKDSGDLLVELAVIICAYQNGKDLQEQDFKELKELLERTLERAGCALDDIVADLGLEELLGSIGVSTGDIIQGLYKLLKELKIDETVFNAVCDVTKKMLDNKCLPKILQGDLVKFLKDLKYKVCIEGGDPELIIKDLKIILERLPCVLGGVGLDDLFKNIFVKDGILSFEGIAKPLGDLLILVLCPNVKNINVSS
What is the function of this protein?
Acts as a surfactant (PubMed:24442854, PubMed:18689424).  Is the major protein constituent (45%) of foam nests (PubMed:27460953).  Has no antimicrobial activity, no larvicidal activity, and is not toxic to mice (PubMed:18689424).
What are the official names of this protein?
Ranaspumin, Lv-RSN-1.
What are the subcellular locations of this protein?
Secreted.
Protein: RFA2A_ARATH
Sequence: MFSSSQFEPNSGFSGGGFMSSQPSQAYESSSSTAKNRDFQGLVPVTVKQITECFQSSGEKSGLVINGISLTNVSLVGLVCDKDESKVTEVRFTLDDGTGRIDCKRWVSETFDAREMESVRDGTYVRLSGHLKTFQGKTQLLVFSVRPIMDFNEVTFHYIECIHFYSQNSESQRQQVGDVTQSVNTTFQGGSNTNQATLLNPVVSSQNNDGNGRKNLDDMILDYLKQPACTARQQGIHIDEIAQQLKIPKNKLEGVVQSLEGDGLIYSTIDEYHFKHVEL
What is the function of this protein?
Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication.  The activity of RPA is mediated by single-stranded DNA binding and protein interactions.  Required fo cell division in meristems.  Involved in the maintenance of transcriptional epigenetic gene silencing (TGS) at specific loci (including some transposons) by regulating histone H3 acetylation, 'Lys-4' and 'Lys-9' methylation.
What are the official names of this protein?
Replication protein A 32 kDa subunit A, AtRPA32A, RP-A p32 A, DNA replication protein A2 subunit A, Protein SUPPRESSOR OF ROS1, Replication factor A protein 2 A, AtRPA2 A, RF-A protein 2 A, Replicon protein A2 A.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage.
Protein: SYI_STRT2
Sequence: MKLKETLNLGKTSFPMRAGLPNKEPIWQKEWEEAKVYQRRQELNQGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIEQVLAKQGVKRKELDRAEYLKMCRDYALSQVDKQREDFKRLGVSADWENPYVTLTPDYEAAQIRVFGEMAKKGYIYQGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGKGVLDTDTYIVVWTTTPFTVTASRGLTVGADIEYVLVKPAGETRKFIVASELLNSLSEKFAWEEVEVLNTYRGDELNQIVTEHPWDSEVDELVILGEHVTTDSGTGIVHTAPGFGEDDYNVGVANGLEVVVTVNERGIMMENAGPDFAGKFYDKVAPIVMEKLGDLLLAKEEISHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDRTPIMTEETIEHVAKLFEEHGSVIWWERDAKDLLPEGFTHPGSPNGEFTKENDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSSLITSVANHGVAPYKQLLSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTSVDTSNDVRISMDILSQVSESYRKIRNTLRFLIANTSDFNPTTDAVAFEDLRSVDQYMTIRFNQLVKNIRDAYENFEFLTIYKSLVNFINVELSAFYLDFAKDVVYIESAKSLERRQMQTVFYDILVKITKLLTPILPHTAEEIWSYLEFENEDYVQLSELPEAEDFANQDALLEKWNAFMDFRGKAQKALEEARNEKVIGKSLEAHLTIYPDAEVKELLESLNTNLAQLLIVSALTIAEGDVPESAVRFQGVSFTVERAEGEVCDRCRRIDPTTKERSYNATICNHCASIIEENFAEVVAEGFEV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_MYCTU
Sequence: MATLADPRDIILAPVISEKSYGLLDDNVYTFLVRPDSNKTQIKIAVEKIFAVKVASVNTANRQGKRKRTRTGYGKRKSTKRAIVTLAPGSRPIDLFGAPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RBL_CEDDE
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEESQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRIHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREASKWSPELAAACEVWKEIKFEFEAIDVL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPIS_STELP
Sequence: MGRKFFVGGNWKCNGTQESVSKIVDTLNEPTIAANDVVTVVVSPPYVFLPDENAELKHEIQVAAQNCWVKKGGAFTGEVSAQMLANLGITWVILGHSERRTLLGESNEFVGKKAAYAQSEGLGVIACIGELLEEREAGKTFDVCFKQLKSFARFPAKPWDNVVVAYEPVWAIGTGKVASPEQAQEVHVAVRDWLKTNVSEEVASKTRIIYGGSVNGGNSLALAAQEDVDGFLVGGASLKGPEFATIINSVTAKKVAA
What are the official names of this protein?
Triosephosphate isomerase, cytosolic, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAC6_ACIHA
Sequence: MNIKPASEASLKDWLELRNKLWSDSEASHLQEMHQLLAEKYALQLLAYSDHQAIAMLEASIRFEYVNGTETSPVGFLEGIYVLPAHRRSGVATMLIRQAEVWAKQFSCTEFASDAALDNVISHAMHRSLGFQETEKVVYFSKKID
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including amikacin, kanamycin, tobramycin and netilmicin.
What are the official names of this protein?
Aminoglycoside N(6')-acetyltransferase type 1, AAC(6')-Ig, Aminoglycoside resistance protein.
Protein: PB2_I83A8
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPVTNTVHYPKVYKTYFDKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSIYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDSVMGMVGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSHNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDESTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: H2A10_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQPMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.10, HNTX-II.10, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UXUA_SALA4
Sequence: MKQTWRWYGPNDPVTLSDVRQAGATGVVTALHHIPNGEIWSVDEIQKRKAIVEEAGLEWSVVESVPIHEDIKTHTGQYDLWIKNYQQTLRNLAQCGIYTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEIAQAERRFATMSEEDKARLTRNIIAGLPGAEEGYTLDQFRQHLATYKDIDKAKLREHFAYFLKAIIPVADEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVETVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTLREENPKTFHEAAHLHGDVDMYEVVKAIVEEEHRRKAEGSDDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: SH3G2_RAT
Sequence: MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDMEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQASSQPRREYQPKPRMSLEFATGDGTQPNGGLSHTGTPKPAGVQMDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYVEILVALPH
What is the function of this protein?
Implicated in synaptic vesicle endocytosis.  May recruit other proteins to membranes with high curvature.  Required for BDNF-dependent dendrite outgrowth.  Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes (By similarity).
What are the official names of this protein?
Endophilin-A1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2, SH3p4.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Early endosome. Presynapse.
Protein: ASTC_YERP3
Sequence: MEQPSPVTRQSFDEWIVPTYAPADFIVVRGEGSTLWDQQGKSYIDFAGGIAVNALGHGHPAVRAALIEQADKVWHLGNGYTNEPVLRLAKQLIDATFAEKVFFCNSGAEANEAALKLARKYALDNFANKAGQQGEKNQIVAFRNAFHGRTLFTVSAGGQPKYSQDFAPLPGGIHHGIFNDLASAEQLITDQTCAVIVEPIQGEGGVLPADKEFLHGLRALCDRHNALLIFDEIQTGVGRTGELYAYMHYGVSPDVLTSAKALGGGFPIGAMLTTTKYASALSVGSHGTTFGGNPLACAVAGTVLSLINQPTLLAGVKARHQWFIDELAEINARHNVFAEIRGRGLLIGCVLNAQYAGKSKEIVQAAAQYGLIALIAGPDVVRFAPSLIISPKEIKEGLARLAMGIEQVCQKVTS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: FENR_SPIOL
Sequence: MTTAVTAAVSFPSTKTTSLSARSSSVISPDKISYKKVPLYYRNVSATGKMGPIRAQIASDVEAPPPAPAKVEKHSKKMEEGITVNKFKPKTPYVGRCLLNTKITGDDAPGETWHMVFSHEGEIPYREGQSVGVIPDGEDKNGKPHKLRLYSIASSALGDFGDAKSVSLCVKRLIYTNDAGETIKGVCSNFLCDLKPGAEVKLTGPVGKEMLMPKDPNATIIMLGTGTGIAPFRSFLWKMFFEKHDDYKFNGLAWLFLGVPTSSSLLYKEEFEKMKEKAPDNFRLDFAVSREQTNEKGEKMYIQTRMAQYAVELWEMLKKDNTYFYMCGLKGMEKGIDDIMVSLAAAEGIDWIEYKRQLKKAEQWNVEVY
What is the function of this protein?
May play a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power.
What are the official names of this protein?
Ferredoxin--NADP reductase, chloroplastic, FNR.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=In the vicinity of the photosystem I in the non-stacked and fringe portion of the membrane.
Protein: RL3_SHESH
Sequence: MAIGLIGRKVGMTRIFAEDGVSIPVTVIEIASNRVTQVKTLETDGYRALQVTTGTKKANRITKPEAGHFAKAGVEAGRGLWEVRLADGEGESIEVGAELNVDIFADVAKVDVTGQSKGKGFQGGIKRWNFHAQDMTHGNSLAHRSNGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLDVVRVDAERNLLLVKGAVPGATNGNLIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ISPE_COLP3
Sequence: MTCASNSNSFLNKAIEFPSPAKINLFLHIVGQREDGYHNLETLFQFIDHSDTLTLTATETPDIELLTPIDGVNNDDNLIVKAARLLKNRSNTDLGVKISINKILPMGGGLGGGSSNAATVLVALNLLWQCEFSLSELSSLGLSLGADVPIFIHGFSAFAQGVGDHLTAIKPQESWYLITKPECSISTKEIFTAVDLPRNTKKLDPTALNTSDFVTESFHNDCQTLVIKQYPEVAKLLAWLVEYAPSRMTGTGACVFTQFSSYQEARSLQAKLPKGISSFVAQGLNKSPLCSVIAKLSLSE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CYSD_PARD8
Sequence: MSDYKLSHLQELEAESIHIIREVAAEFENPVMLYSIGKDSSVMVRLAEKAFAPGKVPFPLMHIDSKWKFKEMIEFRDSYAKKFGWNLIVESNMEAFHAGVGPFTHGSKVHTDLMKTQALLHALDKYKFDAAFGGARRDEEKSRAKERIFSFRDKFHQWDPKNQRPELWDIYNARVHKGESIRVFPLSNWTELDIWQYIRLENIPIVPLYFAKERPCVEIDGNLIMADDDRLPEQYRDQIRMRMVRFRTLGCWPLTGAVESEADTIEKIVEEMMTTTKSERTTRVIDFDQDASMEQKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: DIAA_YERP3
Sequence: MLERIKGCFTESIQTQIAAAEALPDAISCAAMALVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNADNVVLTAITNDRLHDEVYAKQVRALGQAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGQLDVEIRIPSHRGARVQELHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: CTSR3_MOUSE
Sequence: MSQHFHHNPVRVKSGSLFATASEALQARLSKIKRKDKECQAYFRKVIKSTFFQIVMITTVTTNSFLLVLGTNYDIQFEFFRTFEVSELFFVSVYVCEFLMKVYVDPITYWKDGYNILDVIILIILTIPYLLRKIKGNHSAYLHFADGIQSLRILKLISYSRGIRTLIIAVGETVYTVASVLTLLFLLMFVFAILGFCLFGVTDRGDLENWGNLASAFFTLFSLATVDGWTDLQEELDKRKFTVSRAFTILFILLASFIFLNMFVGVMIMHTEDSMKKFERDLTLERNLAIMEEKQIILKRQQEEVNRLMNTQKSGSMNFIDMVEGFKKTLRHTDPMVLDDFSTSLSFIDIYLVTLDNQDVIVSKLQELYCEIVNVLSLMLEDMPKESSSSLSGLS
What is the function of this protein?
Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation.  Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization.  Activated by intracellular alkalinization.
What are the official names of this protein?
Cation channel sperm-associated protein 3, CatSper3.
What is the protein family that this protein belongs to?
Belongs to the cation channel sperm-associated (TC 1.A.1.19) family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.