PharMolix/UniProtQA huggingface dataset:
Protein: GPHR_XENLA
Sequence: MSFFADSVLMVISQLLFFGFGWLFFMRQLFKDYEVRQYVVQVVFSVTFAFSCTMFELIIFEILGLLNSSSRYFHWKLNLCVILLVLVFVVPFYIGYFVVSNIRLLHRQRLLFSCTIWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDADILALERRLLQTMDMIVSKKKRIAAVRRNMFQRGEEHSKPSGFWGMIKSVTSSAPVSENLYQIQQEVDALEELSRQLFLETADLHATKERIEYSKTFQGKYFNFLGYFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAL
What is the function of this protein?
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance (By similarity).  Plays a role in lymphocyte development (By similarity).
What are the official names of this protein?
Golgi pH regulator, Protein gpr89b.
What is the protein family that this protein belongs to?
Belongs to the Golgi pH regulator (TC 1.A.38) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RS8_SACD2
Sequence: MSMQDPIADMLTRIRNAQQVGKTSVTMPSSKLKKSIAGVLKEEGYVGEFSVNDAAKAELTVELKYFEGKPVIAELDRVSRPGLRSYVGKDELPSVRGGLGIAIVSTSKGVMTDRAARAAGVGGEILCTVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NOP9_YEAS1
Sequence: MGKTKTRGRRHQDKQRKDEFEPSSNSAKEHIQQEESTYNDEAEIKETQPQMFFGVLDREELEYFKQAESTLQLDAFEAPEEKFQFVTSIIEEAKGKELKLVTSQITSKLMERVILECDETQLKDIFQSFNGVFFGLSCHKYASHVLETLFVRSAALVERELLTPSFDNNEKEGPYVTMENMFLFMLNELKPHLKTMMNHQYASHVLRLLILILSSKTLPNSTKANSTLRSKKSKIARKMIDIKDNDDFNKVYQTPESFKSELRDIITTLYKGFTNGAESRSDISQSTITKFREYSVDKVASPVIQLIIQVEGIFDRDRSFWRLVFNTADEKDPKEESFLEYLLSDPVGSHFLENVIGSARLKYVERLYRLYMKDRIVKLAKRDTTGTFVVRALLEHLKEKDVKQILDAVVPELSMLLNSNMDFGTAIINASNKQGGYLRDDVIAQLIQKYYPEKSDAKNILESCLLLSASTLGNTRDDWPTAEERRRSVFLEQLIDYDDKFLNITIDSMLALPEERLIQMCYHGVFSHVVEHVLQTTRVDIIKRKMLLNILSKESVNLACNVYGSHIMDKLWEFTAKLTLYKERIAKALVLETEKVKNSIYGRQVWKNWKLELYVRKMWDWKKLIKEQEFEIFPNSKPLQPKPEKHSRERNNSKEGSAFKKQKHYR
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Component of the 90S pre-ribosome involved in production of 18S rRNA and assembly of small ribosomal subunit.  Component of the pre-40S ribosome required for release from the nucleolus (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DDX3_XENLA
Sequence: MSHVAVENVLNLDQQFAGLDLNSADAESGVAGTKGRYIPPHLRNKEASRNDSNWDSGRGGNGYINGMQDDRDGRMNGYDRGGYGSRGTGRSDRGFYDRENSGWNSGRDKDAYSSFGSRGDRGKGSLFNERGSGSRRTDDRRQDGFDGMGNRSDKSGFGRFDRGNSRWSDDRNDEDDWSKPLAPNDRVEQELFSGSNTGINFEKYDDIPVEATGSNCPPHIESFHDVTMGEIIMGNIQLTRYTRPTPVQKHAIPIIIEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGDAMKHLQENGRYGRRKQFPLSLVLAPTRELAVQIYEEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRQTMMFSATFPKEIQILARDFLDEYIFLAVGRVGSTSENITQKVVWVEEMDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNINITKDLLDLLVEAKQEVPSWLENMAYEQHHKSSSRGRSKSRFSGGFGAKDYRQSSGAGSSFGSSRGGRSSGHGGSRGFGGGYGGFYNSDGYGGNYGGSSQVDWWGN
What is the function of this protein?
Multifunctional ATP-dependent RNA helicase.  The ATPase activity can be stimulated by various ribo-and deoxynucleic acids indicative for a relaxed substrate specificity.  In vitro can unwind partially double-stranded DNA with a preference for 5'-single-stranded DNA overhangs.  Involved in many cellular processes, which do not necessarily require its ATPase/helicase catalytic activities.  Involved in the regulation of transcription and translation initiation.  Involved in innate immunity (By similarity).  Involved in both stress and inflammatory responses (By similarity).  May negatively regulate extrinsic apoptotic signaling pathway via death domain receptors.  May be involved in mitotic chromosome segregation (By similarity).  Required for canonical Wnt signaling involved in anteroposterior neural patterning (PubMed:23413191).
What are the official names of this protein?
Putative ATP-dependent RNA helicase an3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Cytoplasm. Cytoplasm, Stress granule. Inflammasome. Cell projection, lamellipodium. Note=Shuttles between the nucleus and the cytosol.
Protein: GOG8J_HUMAN
Sequence: MAEETQHNKLAAAKKKLKEYWQKNSPRVPAGANRNRKTNGSIPEKATSGGCQPPRDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFKEPNNENKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPMPSVPEDPESREAMSSFMDHLEEKADLSELVKKKELCFIHHWRERCHQKTHHLLSEPGGRAKDAALGGGHHQAGAQGGDEGEAAGAAADGIAAYSNYNNGHRKFLAAAHNSADEPGPGAPAPQELGAADKHGHLCEVSLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPGLGSNCCVPFLCWAWLPRRRR
What are the official names of this protein?
Golgin subfamily A member 8J.
What is the protein family that this protein belongs to?
Belongs to the GOLGA8 family.
Protein: RISB_PECCP
Sequence: MNVIEGVVATPDARVAIAIARFNHFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLTVRALTKSAKNGGYDAVIALGTVIRGGTAHFEFVAGECSSGLSSVAMDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: 3BHS_PIG
Sequence: MAGWSCLVTGGGGFLGQRIVHLLLEEKDLQEIRVLDKVFKPEVREEFSKLQSKIKLTMLEGDILDEQCLKGACQGASVVIHTASIIDVVNAVGRETVMKVNVKGTQLLLEACVQASVPVFIHTSSIEVAGPNSYREVIQNACEEDRLETAWSAPYPLSKKLAEKAVLEANGWALQNGGTLHTCALRPMYIYGEGSPFIFAHMNKALENNGVLTHNSKFSRVNPVYVGNVAWAHILALRALRDPRKALSVQGQFYYVADDTPPQSYDDLNYTLGKEWGFCLDSRRSLPPSLRYWLAFLLEIVSFLLSPIYNYQPPFNRHFVTLCNSVFTVSYKKAQRDLGYEPLFTWEEAKQKTKAWVGSLVKQHKEALKTKTH
What is the function of this protein?
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids.  The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase, 3-beta-HSD.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: TBA1_CHLRE
Sequence: MREVISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRCIFLDLEPTVVDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLALDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVMLDNEAIYDICRRSLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNAAFEPASMMVKCDPRHGKYMACCLMYRGDVVPKDVNASVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNSTAIGEIFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDFEEVGAESAEGAGEGEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ATPB_CHLPB
Sequence: MQEGKISQIIGPVVDVDFQEGGLPAILDALTVARPDGTKLVLETQQHLGEERVRTISMDATDGLVRGMPVINTGKPIQVPVGPNVLGRMLNVVGDPIDGKGPVKSEKSYSIHRPTPKFDVLSTKSEMFETGIKVIDLLEPYSRGGKTGLFGGAGVGKTVLIMELINNIAKQQSGFSVFAGVGERTREGNDLWEEMKESGVIDKTALVFGQMNEPPGARARVALTGLSIAEYFRDEENRDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLGTEMGELQDRIVSTNKGSVTSVQAIYVPADDLTDPAPATAFTHLDATTVLSRSIAELGIYPAVDPLDSTSRILDPNIVGDEHYNTAQAVKSLLQRYKDLQDIIAILGMDELSDEDKLTVSRARKIQRFLSQPFFVAEAFTGLEGKYVKLEDTIKGFNEIIDGKHDDLPESAFYLVGTIEEAVEKAKTL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SSUD1_RHILO
Sequence: MTGDVPDRIKVLWFLPTHGDSRYLGTAEGGRSVDLPYLTQVAKAADTLGYYGVLLPTGRSCEDSWVIASALVPLTERLRFLVAVRPGLQSPTLAARMTATLDRISNGRLLINVVTGGDPLENKGDGIFLSHAERYEVTQEFLRIYKRVLSGETVEHQGKHLHIEDGRLLFPPVQTPYPPLYFGGSSDAGSTVAAQEIDKYLTWGEPPADVERKLDAVRELAEKAGRKLSFGIRLHVIARETTEEAWAAADRLISRLDDATIASAQKVFARMDSVGQARMSALHGGDRAKLEIAPNLWAGVGLVRGGAGTALVGDPDTIAERIDEYRRLGIDTFILSGYPHLEEAYRFGELVLPKLPTDHPVKATGSSVNTGPFGETIAGDHRPKSLASAS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase 1, FMNH2-dependent aliphatic sulfonate monooxygenase 1.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: YADL_ECOLI
Sequence: MMTFKNLRYGLSSSVVLAASLFSVLSYAATDSIGLTVITTVEMGTCTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKRATCEGTANDGAGFANGSTAADKASAVAVEVWSTVTPATGSATQFSCVTPASQEVTISTAANAVVYYPMSARLVVEKNKTVNNVTAGKFSAPATFTVTYN
What is the function of this protein?
Part of the yadCKLM-htrE-yadVN fimbrial operon.  Could contribute to adhesion to various surfaces in specific environmental niches.
What are the official names of this protein?
Uncharacterized fimbrial-like protein YadL.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: LEPA_NITOC
Sequence: MGLSISHSMKNIRNFSIIAHIDHGKSTIADRFIQICGGLSKREMAQQVLDSMDLERERGITIKAQSVSLNYCGRNGEVYHLNFIDTPGHVDFSYEVSRSLAACEGALLVVDASQGVEAQSVANCYTAIEQGLEVVPVLNKIDLPSAEPERVCQEIEEIIGLDASDALQVSAKTGQGIEELLAALVARVPPPQGDPASPLRALIIDSWFDNYLGVISLVRVVDGCLKPKDKIKIMSTGQHYRVEKAGLFTPKRREVEQLLTGGVGYIIAGIKDVDGAPVGDTVTHVEQFATKALPGFKAVKPQVFAGLFPVDSDDYEDLREALAKLRLNDAALFYEPETSQALGFGFRCGFLGMLHMEIIQERLEREYSLNLITTAPTVVYQVLTSKGEVLRIDNPSILPEPGQVAEVREPIIQADILVPQQYVGAVIGLCEEKRGTQKQLQYLGNQISLNYELPLSEVVLDFFERLKSVSRGYASLDYHFSRFQSADLVKLDLLINGERVDALSLIVHRNQAHYRGRELAEKMRELIPRQLFDVAIQAAIGAHIVARTTVKALRKNVTAKCYGGDITRKRKLLEKQKAGKKRMKQVGSVEIPQEAFLAVLKVGKKP
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2302_BACAN
Sequence: MKKTFYHYMMKHRAALFSNEISNLAEAMYDDLSFPKQSEDYDEISSYLELSGMLESMSIFDEAWDLYIQDR
What are the official names of this protein?
UPF0346 protein BA_2302/GBAA_2302/BAS2147.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: ALR_JANMA
Sequence: MPRPLIATIDIAALRSNLALAKARAPHSKAWAVVKANAYGHGLERGMRGFAAADGLGLIELDAAARLRELGWNKRILLLEGFFDASDTKLLAEHRLDTVIHCEEQLLMLEQAKLRTQIDVHLKLNSGMNRLGFTPARYRAAYERLRAIPAVRHISFVTHFANAEDPDNPVLPVQEQVRRFKEATRDLPGEKSLANSATDLLHPAAAADWIRPGIMLYGATPGAQSAEQFGLRAAMSLHSEIIGVQHIVAGDAVGYGSAFVATAPMTIGVVACGYADGYPRHAPSGTPVIVDGVKTRMVGRVSMDMITVDLTPVAKPRIGSKVTLWGASLPIDEVANAAGTVGYELMCGLAPRVQIVEVN
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: NU6C_DRANE
Sequence: MDLPGPIHDFLLVFLGFGLLVGGLGVVLLPNPIFSAFSLGFVLVCISLFYILSNSHFVAAAQLLIYVGAINVLIIFAVMFMNDSEYSTDFTLWTVGDGITSLVCTTLLFSLISTILDTSWYRVIWTTRLNQILEQDLISNSQQIGIHLSTDFFLPFELISIILLVALIGAISVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LIPA_SHEDO
Sequence: MNRPERLQPGVKLRDADKVARIPVKIVPSERETMLRKPDWLRVKLPASNQRILEIKAALRKNGLHSVCEEASCPNLSECFNHGTATFMILGAICTRRCPFCDVAHGRPLKPDAEEPVKLAQTIRDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRKLNPDIKIETLVPDFRGRIDAALDILSAEPPDVFNHNLETAPAHYRKARPGANYQWSLDLLKRFKERHPHIPTKSGLMMGLGETNEEIAEVLRDLRSHNVEMLTLGQYLQPSKFHLPVVRYVPPAEFDELKVLADELGFTHAACGPMVRSSYHADLQAQGKEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSHB_PIG
Sequence: MKSLQFCFLFCCWKAICCNSCELTNITITVEKEECNFCISINTTWCAGYCYTRDLVYKDPARPNIQKTCTFKELVYETVKVPGCAHHADSLYTYPVATECHCGKCDSDSTDCTVRGLGPSYCSFSEMKE
What is the function of this protein?
Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer.  Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways.  Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
What are the official names of this protein?
Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted. Note=Efficient secretion requires dimerization with CGA.
Protein: YHAJ_ECOLI
Sequence: MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFNGK
What is the function of this protein?
Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity).
What are the official names of this protein?
Probable HTH-type transcriptional regulator YhaJ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GLHA_HUMAN
Sequence: MDYYRKYAAIFLVTLSVFLHVLHSAPDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSYNRVTVMGGFKVENHTACHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_ALIFM
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLKVTMMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMTKRNNFTAGRVYADVLRKERRGDYLGATIQVIPHITNAIKERVISGAEGHDIAIVEVGGTVGDIESLPFMEAIRQLAVELGRERAMFMHLTLVPYLGAAGELKTKPTQHSVKELLSIGIQPDILVCRSDRVIPANERKKIALFCNVQEKAVISMKDVDSIYKIPQLIKAQGTDDLVCQRFGITAPEADLSEWEQVIYEEANPTGDVVIGMVGKYIELPDAYKSVNEALKHAGLKNRLNVTIKYVDSQDVESKGTEILEGLDAILVPGGFGDRGVEGKILAAQYARENKVPYLGICLGMQVALIEYARNVANMEGAHSSEFSKDTKFPVVGLITEWIDSEGNVEERTEKSDLGGTMRLGSQLCHLAKGSKARELYGNATVEERHRHRYEVNNNLLPQLEKAGLKVSGLSADKKLVEIIEIPNHPWFVAAQFHPEFTSTPRDGHPLFEGFVKAAGESVRGELEK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PRMC_CHLAA
Sequence: MTIQQAIQHAITQLRTISPTARLDAELLLAHILGWSRAKVVAERDHVLTPEQEMAFNALIERRANREPVAYLIGHREFFGLDLFVDRRVLIPRPETELLVELTLKEAQRFNHTPLIIADIGTGSGAIAIALAMHLPHALIYGVDISPDALAVAAINVTRYRLDDRIRLLEGDLCTPLPAPVDILVSNPPYTILTEIDEGVYRHEPHLALDGGSDGLDCYRRLIAAAPTYLKPNGAILLEIGSTQAASVVHLLRQALPMAETGIERDLAGHDRIVWARNRYVIH
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: OLEO5_ARATH
Sequence: MADVRTHSHQLQVHPQRQHEGGIKVLYPQSGPSSTQVLAVFVGVPIGGTLLTIAGLTLAGSVIGLMLAFPLFLIFSPVIVPAAFVIGLAMTGFLASGAIGLTGLSSMSWVLNYIRRAGQHIPEELEEAKHRLADMAEYVGQRTKDAGQTIEDKAHDVREAKTFDVRDRDTTKGTHNVRDTKTT
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth (By similarity).
What are the official names of this protein?
Oleosin 5.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface (By similarity).
Protein: IF3_PHEZH
Sequence: MQAPPVKEGPRMNEDIRVPRVLLIDQHGEKQGVMPTSAAIEAAEEAGLDLVEIVPNADPPVCKILDYGKFKFQEQKKKNEARKKQKVVELKEIKLRPNIDQHDYEVKARSMHRFFEEGDKVKITLRFRGRELAHPELGMKLLQKVKVDFEEVAKVEYEPRMEGRQMIMILAPR
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: X_HBVF4
Sequence: MAARMCCQLDPARDVLCLRPVGAESRGRPLPGPLGALPPSSASAVPADHGSHLSLRGLPVCSFSSAGPCALRFTSARRMETTVNAPWSLPTVLHKRTIGLSGRSMTWIEEYIKDCVFKDWEELGEEIRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.