PharMolix/UniProtQA huggingface dataset:
Protein: TCAM1_MOUSE
Sequence: MDNPGPSLRGAFGILGALERDRLTHLKHKLGSLCSGSQESKLLHAMVLLALGQDTEARVSLESLKMNTVAQLVAHQWADMETTEGPEEPPDLSWTVARLYHLLAEENLCPASTRDMAYQVALRDFASQGDHQLGQLQNEAWDRCSSDIKGDPSGFQPLHSHQGSLQPPSASPAVTRSQPRPIDTPDWSWGHTLHSTNSTASLASHLEISQSPTLAFLSSHHGTHGPSKLCNTPLDTQEPQLVPEGCQEPEEISWPPSVETSVSLGLPHEISVPEVSPEEASPILPDALAAPDTSVHCPIECTELSTNSRSPLTSTTESVGKQWPITSQRSPQVPVGDDSLQNTTSSSPPAQPPSLQASPKLPPSPLSSASSPSSYPAPPTSTSPVLDHSETSDQKFYNFVVIHARADEQVALRIREKLETLGVPDGATFCEEFQVPGRGELHCLQDAIDHSGFTILLLTASFDCSLSLHQINHALMNSLTQSGRQDCVIPLLPLECSQAQLSPDTTRLLHSIVWLDEHSPIFARKVANTFKTQKLQAQRVRWKKAQEARTLKEQSIQLEAERQNVAAISAAYTAYVHSYRAWQAEMNKLGVAFGKNLSLGTPTPSWPGCPQPIPSHPQGGTPVFPYSPQPPSFPQPPCFPQPPSFPQPPSFPLPPVSSPQSQSFPSASSPAPQTPGPQPLIIHHAQMVQLGVNNHMWGHTGAQSSDDKTECSENPCMGPLTDQGEPLLETPE
What is the function of this protein?
Involved in innate immunity against invading pathogens.  Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis (PubMed:12855817, PubMed:16002681, PubMed:21703541).  Ligand binding to these receptors results in TRIF recruitment through its TIR domain (PubMed:12855817, PubMed:16002681, PubMed:21703541).  Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively (PubMed:12855817, PubMed:16002681, PubMed:21703541).  Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens (By similarity).  Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines (PubMed:21703541).
What are the official names of this protein?
TIR domain-containing adapter molecule 1, TICAM-1, Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, TIR domain-containing adapter protein inducing IFN-beta.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasmic vesicle, autophagosome. Mitochondrion. Note=Colocalizes with UBQLN1 in the autophagosome. Colocalizes in the cytosol with DDX1, DDX21 and DHX36 (PubMed:21703541). Colocalizes in the mitochondria with DDX1 and poly(I:C) RNA ligand (PubMed:21703541). The multi-helicase- TICAM1 complex may translocate to the mitochondria upon poly(I:C) RNA ligand stimulation (PubMed:21703541).
Protein: SLLC2_MACLB
Sequence: MGRSISVSFGLLAVFLSLSGTGAGLDCPPDSSPYRYFCYRVFKEQKNWADAERFCAERPNNGHLVSIESMEEAEFVAQLLSKITGKFITHFWIGLRIEDKKQQCRSEWSDGSSVSYDNLLKREFRKCFGLEKGTGYRSWFNLNCEEPYPFVCKVPPNC
What is the function of this protein?
Regulatory subunit of the blood coagulation factor X-activating enzyme.  Activates coagulation factor X (F10) by cleaving the Arg-Ile bond at position 234, activates coagulation factor IX (F9) by cleaving the Arg-Val bond at position 226 and is also able to activate protein C (PROC).  May serve as an exosite by which the enzyme recognizes and binds to the Gla domain of factor X (F10) in a calcium-dependent manner.
What are the official names of this protein?
Snaclec coagulation factor X-activating enzyme light chain 2, VL factor X activator light chain 2, VLFXA light chain 2.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: COWN_RHOP2
Sequence: MSGSFDRYVSFKNSNWEVRSERVMARLQKHIDAAENPFWAYFAQKRIELREKQGLDDLRVLHNYLPTLRELLEDNGDLETLAMLEELEVTLM
What is the function of this protein?
Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO).  Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
What are the official names of this protein?
N(2)-fixation sustaining protein CowN, CO weal-nitrogenase.
What is the protein family that this protein belongs to?
Belongs to the CowN family.
Protein: YFE5_CAEEL
Sequence: MRFFAVLLVPLVFAEICPMDKHAICNTGHLSCTCSVSQEDEAPVPEISCNALIARDLETGNFPVVSVEFDLNNSAEALEEFPEDAFRDKISSSLRVDEEDVIVLRTSCVGTDDTLTIQFVILKKDTNSSALPFAIEDLIDAESIATRMKAMGHLSQIANLDVDTIEYTEELVDLEFEPSNLELIFKAILLALIFGFFFVLGVWKLTKKGDEYADDLQKP
What are the official names of this protein?
Uncharacterized protein F13C5.5.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: FAS2_SCHAM
Sequence: MRTVACAVLLACFMGCLAGAWAQSAGLEILPNSENQTKPIGRSMLLTCKPNVTNKNLISQLRWTDPSGREVPFKNPTLLKPHIFVDWLPPPGEKVLTLMIPELREADTGTYTCSALYSNTKQLSKSVHVRTIMPITWDDAPEEQYPTVNETFKIRCRVSANPPAIVNWMRDGHIVETGDRYVVEQDGLTILNVTEMDDGTYTCRAIVIATGEMALRPIRVEVHTPPQMSGALPPKLEAVEGTDFTAKCAASGKPVPRYTWIRVDTARDLTKDGDRVSADVLLGELRIREVRPEDAANYSCTAKNAAGTATATVEVTVVVRPRIGRFDNISVASGKDSEAVLECHATGSPLPAVTFRKLSNPNRYINGIQPTEDRITVDGVDSPDGRTRIGKLIISNVLRSDDGLYECIATNKGGEVKKNGHLMVEFKPSFADTPQKEVWGWEQHAVNLTCLAHSIPNATISWHFNGADLFRGREGQELQQTGYTLFGSGPRSTLQVIPFNRKMYGNYKCTATNKHGTAVHEIMLREARVPSAVLQVKMDVMTATTVTFKFFGPGNDGGLPTKNYAVQYKQDSQGWEDALNRTWPVDSPYILENLKPQTRYNFRFAAQNEVGFGPWSSQQTHTTPRISAPEEPRLLGLPLSATSGTENEVVVSPYPNRYELRWQVPADNGEPITHYSVKSCPVEKYDTEWRLLPYPCQEHKLEGQATTFQLESLQPDTHYKVEVRATNAIGNSVPGQIIVRTVKDPSQMPGVANVEDGSEGQMSSAAIVVLVVAALLLALLVVDLVCCLVWRGGLIAALCHRCCSAAKTDDSDAKIASLYSWRFPLPYCSNKEDPAMLAPAKMQQATVKIPVIEEKEPLRDGKEPVPIIKERVKRETAVDFDVKKSVSRTSFVGKDSAV
What is the function of this protein?
Neuronal recognition molecule.  Involved in a pathway recognition for axons during the development of nerve fascicles.
What are the official names of this protein?
Fasciclin-2, Fasciclin II, FAS II.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: OBG_BIFAA
Sequence: MSDFVDRVTVHVKGGDGGNGSAGIRREKYKPLAGPNGGNGGDGGSVIFMADSNANSLLDYRFMPHREAESGTMGLGDTKDGSKGADLILPVPVGTVVFEAKGPQGKPKHPGEQLADLRHAGDKFVVAAGGNGGLGNAALANRTRRAPGFALLGEPGEERDVILELKSIADVALVGFPSAGKSSLIAAMSSAKPKIADYPFTTLVPNLGVVVAGDMRYTIADVPGLIPGASQGKGLGLEFLRHIERTEIIAHVIDCATLEPGRDPMSDYQALEHELAEYAGKLELPLGAIPIPERPRIIILNKVDVPEAKELAEFVKPEFEKLGLKVHIISTASHEGLKELNWALADLVTNMRAEVAKREQAEEEARVVIKPLEEPRNRRRRNDEGGNALDFTVERKENGNGEVWYEVLGTKPERWVMQTNFDNDEAVGYLADRLAKLGVEDELRHKGAKPGDEVRIGRGDRAVEFDWDPTIAAGAEMLDGTQLGARGVDLRLQESDGRAQRRSNTERRRQYHEMMDARQAVREAMMAERKAGHWADPSVDDDRHDETSLFGRGETADDEDVEQ
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_STRT2
Sequence: MIDFPIKYRLIKKEKYTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELQQMGSGIILANTYHLWLRPGDELIAKAGGLHKFMNWDQAILTDSGGFQVYSLAEKRDISEEGVTFKNHLNGSKMFLSPEKAISVQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSSHDLVSMDFPGYSIGGLAVGETHEEMNAVLDFTVPLLPENKPRYLMGVGAPDSLIDGVIRGVDMYDCVLPTRIARNGTCMTSNGRLVVKNAAYAEDFSPIDPECDCYTCKNYTRAYVRHLLKADETFGIRLTSYHNLYFLVNLMAKVRQAIVDDNLLEFRQDFIEKYGYNASNRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: LIGB_CHRSD
Sequence: MSRRPVWIDGSDMRPAPLRTAAWLRACLLVGLSTLAMPGWASAPPCPQMTPEAMQNDYQALDARIARWDRAYYRQGQRLVDDGTYDSAKRRLAHWAECFPLLAKPSVNTHEPTGAKHHPVAQTGIAKLPDRDAVAGWVARQGDHPLWVQPKVDGVAVTLVYRHGRLAAAISRGDGVSGQDWYTKALHIAAIPSHLPADAPPLVILQGELYARRTAHRQSRDGTDGARARIAGLMARDTLTDREGSTIGLFVWAWPNGPDTMPERLETLAGWGFGDVAEMTHGVATAEDIAAWRQRWYRHALPFATDGVVVKRGDRPPGSDWQASPPDWAMAWKYPAREALARVDALEFSVGRTGRIAVVAELEPVLLGDKRVTRVSLGSLAHWRRTDVRPGDQVRLRLAGLTIPQLQEVVVRTRPRPQVDAPEADQYDRLSCLRFTPACRDQFLARLEWLGSDEGLDFPGIGPATWNQLVDAGLVKGLLDWRTLDTAALEALPGVGKKTARAWQRHFALADTRSAVRWLRALGVPAVPRQALTDALERYGMAGLGTLAPPDWRDYSGIGETRAMQLTRFFRDTDIRHWLASLESTRALQKQHGTNTRNEQKGDVRRVDVKQDNGTTWLPEQDSNLRPND
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: DAPE_CUPNH
Sequence: MTATLALTEDLIRRRSVTPADEGCQAILETRLKALGFDCEALVSGPDDFRVTNLWAVRRGTQGKDGKLLVFAGHTDVVPTGPLEQWHSDPFAPTHRDGKLYGRGAADMKTSIAGFVVAVEEFVKAHPAHAGSIAFLITSDEEGPAHDGTIKVVEALSARGERLDYCVIGEPTSVDTLGDMVKNGRRGSLSGKLTVKGIQCHIAYPHLGRNPIHEAAPALAELAAEVWDQGNEYFPPTSWQMSNIHGGTGATNVIPGHVTIDFNFRFSTASTPEGLKARVHAILDRHQLEYALDWTLGGEPFLTPRGELSDALSSAIEAETGVKTELSTTGGTSDGRFIAKICPQVIEFGPPNASIHKIDEHVEVRFIEPLKNVYRGVLERLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: TLN_OSCPE
Sequence: MASLALRINIVDQNNVKTMQFEPSMIVYDACKMIRERIGEKPAAGQGYGLFLANEDPKRGVWLESGRTLDFYLLKPGDLLEYKNKMRPLRVRMMDESLKTVLVDDSFTVDQLVKTVCDRIGITNNEEFSLVCEDEEATPKKAAPPQIRNQKKMDELKKKLHTEDDVNWLSHDKTLRSQGISESQVLLLRKKFFFSDQNVDRNDPVQLNQLYAQARDAIVDGTHPCTYEEAINLAALQCQIVLGNHDSGKHKPGYITEELGSYLPREYVKAKGVERRVFTEHAKFTGLSQLNAKFRYIQVVRSLKTYGVTFFLVKEKMKGKNKLAPRLLGITRESIMRVDEKTKEVMKTWPLTTVRRWAASPNSFTLDFGDYSESYYSVQTTEGEQISRLIAGYIDIILKKKRATDRKVPEVEDETTLTEDLVLPARATQVSYVTSTSDRGEEGQVAHPGVLRAAGESGALFVPGDFLEGSHIQRQAAQTPGYSPAQQALQSSIAKGLGCADVAINELEAPTQLPPLGSDPQSLKWKQNTLDVSRQNVGSQLAAMTAAAAQMVGLTGADPADIDYTAVGAAVTTLSSNLTELSKGVRMIAALQGNSHDGEKLLEAARGLAGAVRHLLKSAEPSENQNRKDLLDAAAALGISGTQLMALMGDPDVTQEVQDALLSKAKAVAVATSGLVQNAKMVAGKCPDSTLQSSVITATKGTATATSQLVACTKIVASTITNPLCQEQLINSAKQVAGAVEGTVSSAQNACSDDDALRELGMSATKVTDALQDLLRYIRDIEAGGLRGGKYEEQIEMILAATERLINSLGNAQETVKSAKTVAMATSQMVSGVKDEASGLSDEDAKRRLLAAARGLADATAKMVDAAKVSARDPSNVEAQAALKAATEDLRAAVNAAANNALKKKLIKKLEVAAKHTAAAATQCIAAAQGAGPTNRNQSSQQQLLGNCKTVADHIGRLVQAVRASMANPESPSSQLGLINASQAMIQPCGKMIAASKAAVPTIGDQAAALQLANFAKQTATCLAELRTAAGKAAEACGSLEIESAIDVVRQLEADLLSVQRTAASGKFLPLPGETAESCALELGATSKTVGASMAQLLTAAAQGNENYTGIAARDTANALKVLSGSVRGVAAATDDRSAQEQIIVTAIQVMAHSRRLIEEAKKAIASPTNPENQSRLAQAAKAVSQALNQVINCLPGQRDVDAAIKDIAAASVALTTGQFPSAGGQSFQDVQTSLSVSSAALNVSASELVANSRGTHMQLAQSSQKFAGKYKTMLHSGLMLAGLSKEKAARSKIVGYLRSVSMSSSKLLLAAKALSADPNAPNVKNNLAAAARGVTDAINALVTVCTASAPGQKECDNALRKIQTVGGMLANPVEPVNDNSYFVCLDAVMENSKILGEAMGDITKHAKGERHDEFGSAVSTAASAVCTLTESAAQAAYLVAISDSSSTAAISGLVDTSQFARAQQAIREACEQLLNPSSAQQQVLSSATVIAKHTSGLCNACKIASGKTKNPVAKRKFVQSAKDVATSTANLVKSIKALAGTLNDGNRGDCAKTTKPLLEAIDDLVEFASAAEFASVPAQISPEARSAQAPILVAGNNMLIASSSLISSAKNLAVNPRDAATWQLLASHSKAVSDAIRRLVAAVKDKSPGQAECDQAIELLNMAINEVDQATLAAISSKLTPSSQSTLQGFHTQMMGGVSEISDLIEPVALAAKGDAEKLGHMVTNVVSYFVPLSKAAVGAASKTTNPDRQMAVLEQTKTLAESALQLMYAAKESGGNPAAAAAGAHANINEAAGNMTEAVKDLKGTLEMAASEAGLTAGMVDTIHKAAGTLDDPIHGEVSKSFGEYQESMVHSAKIIILKAQDMVGRAGTSPGELGVISKDATTSYCALATDCRGALATADDDVTGARLKAACQQLGDALGDLIQCAGSVQSNPTDAIGRKELSDCAKKVGSKVNFVLAALQAGAKGTQACINAVADVSGIVGDLDTSVMFATAGVLNPDREGDTFGEHREDILKTAKTLVEDTKTLVSGAAASQEQLAKAAVDAVGTITRLADHVKKGAAALTSEDQEAQVLLLNAVRDVASSLGALITATKNASGKSVQDPAMEHLRTCAKAMVSNVSSLLKTVKSVEDEAARGARALESAIDAINAQLEELLSPNEPGRDASPEDIIRVTKGVTLATAKAVAAGNSGRQDDVTASANLGRKAIIDMMLTTKAAALKAESEDSKIRSITAAKECTAAFRSLLELVHSILMKPSHDKKQKLTAYSKEVATCVSEVVQAAEVLKGTDWVDPSDPNIIAENELLNAAASIEAAAKKLALLKPREKKHEADETLSFDEQILEAARAIAAATGALIKSATTAQRELVAQGRLRPGVPGSDDSQWAEGLVSAARMVAAATQSLCEAANSAVQGVSSEEKLIASAKAVAASTAQLLLACQVKADADSENFKRLHKAGGAVKRAAENLVTAAKRSSEEGDDEEVSGGGQERFVGGIAREIEAQEAILRKERELDEAKRQLKKIRHDKYKRHGQDEP
What is the function of this protein?
Probably involved in connections of major cytoskeletal structures to the plasma membrane.
What are the official names of this protein?
Talin.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: LDTI_HIRME
Sequence: KKVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCPTGILN
What is the function of this protein?
Acts as an inhibitor of human tryptase, trypsin and chymotrypsin.  Probably acts to block host defense mechanisms.
What are the official names of this protein?
Leech-derived tryptase inhibitor C, LDTI-C.
Protein: Y724_NITEU
Sequence: MNAMNDKWYSGMARTEDWWAVWLGLIMFMASVSSLWGWELTGWMAKPDTWVWEKFSIEGVLKSSGKPEWHPALSLLVTYLVFTALTCLAAWSMKFDLKQFFIGWTILFIMTWVIWIIGNEAHFKASVYEMDKYGLSWGLSLGSGFSYLLALLVGLVIGNFFKNTARFLNEAAKPEWFIKTAIVFLGIKIGVMSIEAAGFITELVMTGVAATFVAYMLFWPIVYALGRRVFHLSRDAAAVLSSGISICGISAAIATAGAIRARPALPAFVSILVVIFAMFELIILPGFYTAIAPEQPIVNGSALGLTVKTDGADAAAGAMLDELMRANAEANLGIVWKEGWILMASLTTKIWIDMFIGVWAFVLALVWVYKVERKPGQSKIGLMEIWHRFPKFVLGYLLVWFSYIMLASSGSEAAETLHKAAAAVEGPMRNMMFMLTFISIGIITDFSKLKGMGKLALLYAIALFGIIAPIAYGVAWIFHRGMMPPVL
What are the official names of this protein?
UPF0324 membrane protein NE0724.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEPQ_KLEP7
Sequence: MESLAALYKNHIVTLQERTRDVLARFQMDALLIHSGELVNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEEIDVIALPKADGIGSQLPAARGNIGYIGPVPERALGLGIAADKINPKGVIDYLHYYRAYKTDYELACMREAQKSAVNGHRAAYEAFQSGMSEFDINQAYLTATGHRDTDVPYSNIVALNEHASVLHYTKLDHRAPAEMRSFLLDAGAEYNGYAADLTRTWAAHGDNDFAHLIKDVNDEQLALISTMKAGTSYIDYHIQFHQRIAKLLRKHQLVTDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDTGTHLAAPSKYPYLRCTRIIEPRMVLTIEPGIYFIESLLAPWREGPFSKHFNWQKIDAMKPFGGIRIEDNVVIHENSIENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: FABZ_CLOBB
Sequence: MLKIEEIKEILPHRYPFLLIDRVTEMDIEEKLFVKGYKNVSANEQFFQGHYPQEPIMPGVLQIEALAQAGAVAILSMEKFKGKTPLFAGTNKVRFKAKVVPGDRLDLYCEIVKLKGPIGIGKGIASVDGKTVCEAEILFAIG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_BURM9
Sequence: MSTPRIALIAHDAKKDDIVALAGAYRATLAQCRLVATGTTGGRIAQAHGLDVERKLSGPLGGDLQIGAELADGRVDIVIFLRDPMTAQPHDPDITALVRACDVHDVPVATNVATARVLLDDLARRLTANA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: PSBC_NASOF
Sequence: MKTLYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGVGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVCGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: METN2_OCEIH
Sequence: MISIEGLSKVFSLNKKDIKAVDSLTLNIENGDIYGVIGYSGAGKSTFVRLINRLEEPTSGKVTIGDQVITELNKNDLRVARQDIGMIFQHFNLLWSRTVEDNIGFPLEIAGVDKQEKARRVKELIGLVGLEGREKSYPSQLSGGQKQRVGIARALANSPKVLLCDEATSALDPETTNQILSLLQDINEKLNLTIILITHEMHVIRKICNRVAVMEQGKVVEEGQVLDVFTNPKQLVTRKFVEQVMSSNEDSDISTIIENYPDGVLYRVHFLGETTNQTLISQIAKQFSVDLNIIQGNITQTQAGSYGALVVQVTGNESEIERAKSFIESQESVELEVIQHAK
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UTP25_KOMPG
Sequence: MTEANSNRNRSKHARSHYGREELRTVRSVKRRTGGKNNYSKFTPMDNNESIVEESEDEGEEEDDEQEDPQPSSMAYDALLTLLDDESDHEQFHAEKEKALKKLEEEQEREEEELQEEDEDEDEEDEEINLEDFESDDESHDDPFHFHFNEEESIDRMINEYESSGLKVKMDRKVNHNGYNILEYLPSTSRCLNEVKTLDKLRIKKKLRDQFSSLDFKDELDKKLTLDIFNYKNINYQYYTRETDYQSLYLLHALNHLLKTRDRIFDHNNKISADPNLEFKDQGYTRPKILILLPTRNFCFNLMNKLIKLADIKTVENKKRFNTQFYSDFKIETLNGNKPKDFNEFFRGNSSDFFTLGVKFTRKSMKIYSMLKQSDIIFASPLGLKMLLDKEKNDYLSSIEVTILDKADGLLMQNWDHVKQIFTKSLIQAPKNFEELNCDFSRIRMWCINDQAKYVHQVLSFSKYTTPELNNIVKAPNLQGYALYKPIIDDTNNVMNQLNYQLFQSRIINKNIRLNHMFMRFPSSSPMESPKKRLNFFTKVILPNVLTKSPYTSGTLVYISSYLDYIQVKKHLSESRSEFLAVDEYTSLSASSKNRSLFEKGKYPIMLYTERMHFYKRYNLNGVRNVVFYNLPTDPDFYAQVVRQIVRNKLKDEELDLNLCSIKVMFDRFDTLKLEKIVGLKRASLLVNAEQEVFEFK
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DUS_STAAR
Sequence: MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTCKELLDLLRLHLSLFNKYEKDEIRQFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKLEL
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: SYL_STRT2
Sequence: MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYDWDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHDLVDAITSPEQAEAVANYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGREIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVEVLEGGNVEEAAYTEDGPHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIVAENNGGLDKVYNETVKSVTEQIELMKFNTAIAQLMVFVNAANKEDKLYVDYAKGFVQLIAPFAPHLAEELWQTLTATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREELQEVALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_RHORT
Sequence: MIEAEENTLALPRTLVLVGLMGAGKTCIGRRLAQMAGVPFVDADVEIERAAKRTIAEIFATYGESEFRALERRVMARLLAGRTCVLATGGGAFMAEDTRALIRLHGLSLWLRADLDLLVARTAGRTHRPLLNNGDAREKLAELMAKRHPVYAEADIVFDALDESQDASALRVRSCLLSYLADHAETAP
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y182_AERPE
Sequence: MPVNVDRLKDAVEVLGNRVRIRVYVKPEGRERRLRLEEGELVFYTDEPPLEGRANASLINFLARGLKVSVKNIEIVHGARSRSKVVEIRDVADPDALLERLASIVDEG
What are the official names of this protein?
UPF0235 protein APE_0182.1.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: SKP1_ASPFU
Sequence: MTTVTLTSSDGVDITVDRDVAERSILIKNMLEDLGESDEAIPIPNVNEVVLKKVIEWCTHHKNDPPSTGDDDDSRRKTTDIDEWDQKFMQVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPEEIRKTFNIQNDFTPEEEDQIRRENEWAEE
What is the function of this protein?
Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity).
What are the official names of this protein?
E3 ubiquitin ligase complex SCF subunit sconC, Sulfur controller C, Sulfur metabolite repression control protein C.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.