PharMolix/UniProtQA huggingface dataset:
Protein: PUN1_CAPFR
Sequence: MAFALPSSLVSICDKSFIKPSSLTPSTLRFHKLSFIDQSLSNMYIPCAFFYPKVQQRLEDSKNSDELSHIAHLLQTSLSQTLVSYYPYAGKLKDNATVDCNDMGAEFLSVRIKCSMSEILDHPHASLAESIVLPKDLPWANNCEGGNLLVVQVSKFDCGGIAISVCFSHKIGDGCSLLNFLNDWSSVTRDHTTTTLVPSPRFVGDSVFSTKKYGSLITPQILSDLNECVQKRLIFPTDKLDALRAKVAEESGVKNPTRAEVVSALLFKCATKASSSMLPSKLVHFLNIRTMIKPRLPRNAIGNLSSIFSIEATNMQDMELPTLVRNLRKEVEVAYKKDQVEQNELILEVVESMREGKLPFENMDGYENVYTCSNLCKYPYYTVDFGWGRPERVCLGNGPSKNAFFLKDYKAGQGVEARVMLHKQQMSEFERNEELLEFIA
What is the function of this protein?
Participates in the biosynthesis of capsaicinoids in pungent cultivars of Capsicum frutescens.  Capsaicinoids, the alkaloids responsible for the heat or pungency of chili pepper, are synthesized from phenylpropanoid intermediates in the placental tissue of chili peper fruit.  Can transfer an acyl from 8-methylnon-6-enoyl-CoA to vanillylamine forming capsaicin and CoA.
What are the official names of this protein?
Acyltransferase Pun1, Acyltransferase 3, Capsaicin synthase, Protein PUNGENT 1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: GUAA_STRPD
Sequence: MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVLSELKSHKITAQELHEINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSNDCPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEITKIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: CLPX_CLOPS
Sequence: MGKFEDKKQLRCSFCGKNQEQVKRLIAGPGVYICDECIELCSEIIEDEFEGNTESSPLETSNLPKPQEIKDYLDQYVVGQDRAKKSLAVAVYNHYKRINANKAEDDVELQKSNILLLGPTGSGKTLLAQTLAKMLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQINTSNILFICGGAFDGIDKIIEKRGTKSSIGFGAEVKGKSEKNVGELLKDIMPGDLLKFGLIPEFVGRLPVLVTLEALDNEALVSILTKPKNALVKQYKKLFELDNVKLDFTEEALKAIADEAINRKTGARGLRAIVEETMMDIMFDIPSEENIVKATITEETIKDRKDPELEKLPEGEVRPTLKTEKKNKARKDIETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YDAB_BACSU
Sequence: METLQHLILHDMPNSEEIEAVKSGDHTLTYKGYRKRINQLANAMLQKGIQKGDRVALLCKNGHPASTVMFAALEIGAVVVPVSWQLKPYEMTGILKASEPKAMFYGAEFKEILDEVLPELSSLCVTMETGTAYETSAEFEALFAGPDHLPETEMVSPDDTALLMFTSGTTGNPKRCMITHGGIYRYVKKSNSSIARMKGLRFLACHPIYHTSALICIMLGTFAETTFVFTKDQDPVHMLKVIEEEKIQTVMALPVFYTYLLEAWEKHQTDLSSLVILMTGGTKVPSSLISRYLDIGIPLAHGYGSTEAWGISTWTPDMGMDKAASAGKPVAGVKVKVEDPLTGEELPQGEIGEIVVHTPFLFKGYEDNPEATAKVLQNGWFRTGDSGYVDEDGFIFITGRYKDVIIYGGDNVYPDQVEEVIQQIPGILETAVVGIPDPLYGEKPKAFIVKNGGQRITEEDVIAFCKERLSAYKIPEVEFVNELPKNNLGKVKKDVLRNQAVHS
What are the official names of this protein?
Putative acyl--CoA ligase YdaB.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ERA_MYCSS
Sequence: MSEFRSGFVCFVGRPNTGKSTLTNALVGTKVAITSNRPQTTRHTIRGIVHRDEFQIILVDTPGLHRPRTLLGQRLNDLVKTTYSEVDVIGLCIPADEAIGPGDRWIHEQIRAVAPRTTLVVIVTKIDKVPRDRVAAQLMAVSELVGPDAEIVPVSATTGEQLDVLTDVLAGKLPPGPAFYPDGELTDEPEETLMAELIREAALEGVRDELPHSLAVVIDEVSPREDRDDLIDVHAILYVERDSQKGIVIGKGGARLREVGTAARLQIEKLLGTKVYLDLRVKIAKNWQRDPKQLGRLGF
What is the function of this protein?
Exhibits GTPase activity.  Binds RNA but is probably not involved in ribosome assembly in mycobacteria.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: NNAT_MOUSE
Sequence: MAAVAAASAELLIIGWYIFRVLLQVFLECCIYWVGFAFRNPPGTQPIARSEVFRYSLQKLAHTVSRTGRQVLGERRQRAPN
What is the function of this protein?
May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system.
What are the official names of this protein?
Neuronatin.
What is the protein family that this protein belongs to?
Belongs to the neuronatin family.
Protein: LERK_MYCS2
Sequence: MTYLLNSPDDFADEAVRGLVAANPDLLTEVPGGVVRSTETPKGQPALVIGGGSGHYPAFAGWVGPGMGHGAPCGNIFSSPSASEVYSVVRNAENGGGVILGFGNYAGDVLHFGLAAEKLRHEGIDVRIVTVSDDIASNSPENHRDRRGVAGDLPVFKIAGAAIEAGADLDEAERVAWKANDATRSFGLAFEGCTLPGATEPLFHVEKGWMGVGLGIHGEPGVRDNRLGTAAEVADMLFDEVTAEEPPRGENGYDGRVAVILNGLGTVKYEELFVVYGRIAERLAQQGFTVVRPEVGEFVTSLDMAGVSLTMVFLDDELERLWTAPVETPAYRRGAMPAVDRTPRTTTWDAAETTIPEASEGSRECARNIVAVLETFQQVCADNEAELGRIDAVAGDGDHGQGMSFGSRGAAQAARDAVDRNAGARTTLLLAGQAWADAAGGTSGALWGAALTSAGGVFSDTDGADEQAAVDAICAGIDAILRLGGAQPGDKTMVDAAVPFRDALVKAFDTQAGPAITSAARVAREAAEKTADITARRGRARVLGEKSVGTPDPGALSFAMLMKALGEHLTR
What is the function of this protein?
Kinase that has a preference for L-erythrulose, producing L-erythrulose-1P.  Involved in the degradation pathway of L-threitol, that allows M. smegmatis to grow on this compound as the sole carbon source.  Is also able to phosphorylate D-erythrulose and dihydroxyacetone in vitro.
What are the official names of this protein?
L-erythrulose 1-kinase.
Protein: GUAA_LEPIN
Sequence: MVIHKKIAVVDFGGQYAHLIASRIRRLGAYTEILSNEEPISNYQKYSGIILSGGPESVYEPNSPTVTTRIFDLGIPILGICYGHQLIMKLLGGVVERSGTGEYGPASLQLHGTNGNSILKNFVGGEQVWMNHADEVVKLPEGFSKIAFSKDCGYAVVANSSKKIFGIQFHAEVSHSEKGSVLLDNFIQICGVSKTWGIDQFLKEKIKEIQETVKQEQKIFMLVSGGVDSTVSYLLLCKALGAERVLGFLIDTGFMRKDEVVSLQKKLTFQNIHLTVRDESSLFYKSLKDKSDPEEKRKIVGNLFLEARDRAVKDLDLEYGDWLLGQGTIYPDTIESGGTKHSHTIKTHHNRVEAIQKLIEQGKVIEPIRDLYKDEVRDLGVLLGLESEWVGRHPFPGPGLVVRMLAVEKKGTDKDQLEIDSYLSTQDGLSGKILPIASVGVKGDRRSYANCVVLNDIETDWNTLDRVATHLSNRFSFINRVVLLPFESDLKKWNFQFTGMQLDKKCSDLLREADFTVESVIRKLGLYNKIWQMPVVLLPIGEKENEKSIVLRPVESQEAMTANFFRMERSVLQEIKIEVLKIPEIRYLFFDLTNKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
Probable GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NU4LM_FORLA
Sequence: MTPVHFSFTSAFILGLMGLAFYRTHLLSALLCLEGMMLSLFIALALWALQFESTGFSTAPMLLLAFSACEASAGPGLLVATARTHGTDRLQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PANCY_PARMW
Sequence: MLSTQAELAAFHSGLGQPLQFVPTMGGLHQGHGELIRRAAEQGPVLVSVFVNPLQFAPGEDFERYPRSLEADLALADRYGAAALWTPTVQTIYPDGATADSARQAPAALQQHLCGADRPGHFDGVVTVVARLLELTRPAGLWLGEKDWQQLVILRQLVADLVLPVKIHGVATVREADGLALSSRNQYLSAAQRLQAAALPAALRAADGTTPLDVTRSRLSAAGLEVEYVERVDPQSLQPCGSETALSLLAAAVRCGTTRLIDHSFLMTRQPLVAIDGPAGAGKSTVTRAFAERLGLIYLDTGAMYRAVTWLVQQQGVEPGDAAAVDALLRALDLQLQSLPGGGQQVMVNGEDVSQAIRSPEVTGSVSVVAAHRCVRQALTTQQKAMGAKGGLVAEGRDIGSAVFPDADLKVFLTATVAERARRRALDLEQRGFPVQERSELEAQIAERDHLDSTREEAPLVQAIDAVELVTDGMSIDAVIDALVEQFRARVPEEAWPTPAG
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_YERP3
Sequence: MSKPIQMERGVKYRDADKMALIPVKNVVTERQELLRKPEWLKIKLPTDSSRIQGIKAAMRKNGLHSVCEEASCPNLSECFNHGTATFMILGAICTRRCPFCDVAHGRPVTPDANEPEKLAQTIQDMGLRYVVITSVDRDDLRDGGAQHFADCISAIRAKNPTIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRVYRQVRPGANYDWSLKLLERFKEAHPDIPTKSGLMVGLGETNAEIVEVMHDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPAEFDEMKAEAMAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_ECO24
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALPA_ECOLI
Sequence: MNNRSAVRILRLPAVIQKTGMARATIYDWLNPKSPRYDATFPKKRMLGVKSVGWIEAEIDEWLSQRCKLI
What is the function of this protein?
Positive regulator of the expression of the slpA gene (PubMed:7511582).  When overexpressed, leads to suppression of the capsule overproduction and UV sensitivity phenotypes of cells mutant for the Lon ATP-dependent protease (PubMed:7511582).  Part of the cryptic P4-like prophage CP4-57 (PubMed:7511583).  Overexpression of AlpA leads to excision of the CP4-57 prophage by IntA.  This inactivates ssrA (the gene upstream of the prophage) that encodes tmRNA which is required to rescue stalled ribosomes in a process known as trans-translation (PubMed:7511583).
What are the official names of this protein?
DNA-binding transcriptional activator AlpA, Prophage CP4-57 regulatory protein AlpA.
Protein: ISPH_RUTMC
Sequence: MKVLLANPRGFCAGVDRAIEIVERALKLHGAPVYVRHEVVHNKFVVDGLKAKGAIFVEDIADVPNEQVVIFSAHGVSMAVRKQTQDIDATIYDATCPLVTKVHKEVIRKQKQQHQVILIGHKGHPEVEGTLGQSNEELQLVETIEDVGRLNLSKNTPISYTTQTTLSIDDTKHIVDYLKSKFPTIDAPKKDNICYATQNRQDGVKILMQSSDILLVLGSSNSSNSNRLREIAEKMDIPAYLINDADEIDELWLKDVNTIGVTAGASAPEVLVQEVIHYLCDKGVTKVIEVNGAKENIHFPVPKELR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NS1_I57A4
Sequence: MDPNTVSSFQVDCFLWHVRKQVADQELGDAPFLDRLRRDQKSLRGRGSTLGLNIETATRVGKQIVERILKEESDEALKMTMASAPASRY
What is the function of this protein?
Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated RIGI ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors like IRF3 and IRF7.  Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR.  This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm.  Also binds poly(A) and U6 snRNA.  Suppresses the RNA silencing-based antiviral response in Drosophila cells (By similarity).
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm (By similarity).
Protein: SCC1_CAEEL
Sequence: MFYAQFVLAKKGPLAKVWLAAHWEKKLTKAQIFETDVPQAIEEVIRPKVKMALRTVGHLLLGIVRIYSKKTRYLLADTNEAYQKMKINFRNGFSFEVDIPENAEIEEDFSNFIDKYNITVPEFHDADYNEQLIMANVSRREDITMKETVNFNVEFNIDADFDGFGDEGESWQLDHLYGSVEPLSLRPTPQPESLMEVERDRDVAANGTEISRIDADSVIFSEGPTRPNLIFDNQEGGNFMPEMNLKVENQTLENDGGVGPADMFSSMIHPVREHAVADVQNDDGMDFDYQPFEPENVEPSRPQSPESFALEPLDVEHMEGRKKRQRKARKLIVDAETMISNDAFREQQEDFSDTMRVVEMAPPTRKMFNLCVSGDLQHLSREPGCKMFNRELLQRYRRCLVTREFDLNYTMQELSDSSSFTPSMEAQAEPWEDLNLNEDIQEDIQAQGPAVDEFFNDVRMDDDDDRQPAQEMDFGDNFDFPQEVEHQECAPIPIQSGFAGENKENEDAEDWSDPFGSSNSSRRGQLEAYGFGNTSTYKEDDGKWAKRAKHILKKVSADIETSGQADFSSVTATAKNRKQAAEQFYSLLTLAKSQAISVDQSEPYGEIVIRPGANFKEACPLSSPKPMGLGNTMENSTMRTPMRPV
What is the function of this protein?
Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle (PubMed:12827206, PubMed:12808038).  The cohesin complex is required for the cohesion of sister chromatids after DNA replication (PubMed:12827206, PubMed:12808038).  The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity).  At metaphase-anaphase transition, this protein is cleaved and dissociates from chromatin, allowing sister chromatids to segregate (By similarity).
What are the official names of this protein?
Sister chromatid cohesion protein 1.
What is the protein family that this protein belongs to?
Belongs to the rad21 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Shows cell-cycle dependent localization to chromosomes, with an accumulation on chromosomes apparent during mitotic interphase and telephase, but more diffuse nuclear expression during prometaphase, metaphase and anaphase.
Protein: INT13_DROME
Sequence: MFERNQKTIFVLDHTRYFSIASEEYISMDFLKGKPSADGGATGAAGNATGSGGSQFSKSLWTCACESSIEYCRVVWDLFPGKKHVRFIVSDTAAHIVNTWRPSTQNMAHVMNAMLIVGVPSRNVPTSSDYSVIHGLRAAIEALAEPTDEQLAAMADFGTDELPRIPNKGRVICITSARDNTSMKSLEDIFNTVLVQQNTLAAPPSKKGLVIDHCHLVILNIVPLGVESLVTNRSLLKISPLLDVEIHTVSAPDISYKLTHLILNHYDLASTTVTNIPMKEEQNANSSANYDVEILHSRRAHSITCGPDFSLPTSIKQGATYETVTLKWCTPRGCGSADLQPCLGQFLVTPVDVTSRPSSCLINFLLNGRSVLLEMPRKTGSKATSHMLSARGGEIFVHSLCITRSCMDEAPSITDGPGGRVSDYRTAELGQLIKMSRVVPLKVKDPSAPPLTRRLPRYFPLTTSSSILFHLQRHISWLPHFLHLLVKEDMDKQDEVRCQQHIHELYKSASRGDVLPFTHTNGARLKLSKAKDQYRLLYRELEQLIQLNATTMHHKNLLESLQSLRAAYGDAPLKSEPGASLLRTYTESPLSPERLEPISSVGASGSSSSNSLLKASKRRMSSCGQRSLLDIISSAERSQSNKRLDFSGRLCTPLGQVAKLYPDFGTKDKDTVTTGASITPNVKEESVRS
What is the function of this protein?
Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing (PubMed:23097424).  Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1 and U5 (PubMed:23097424).  Plays a role as a regulator of spermatogenesis (PubMed:19357193).  Crucial regulator of the mitotic cell cycle and development (PubMed:15737938, PubMed:19357193).  Required for the correct dynein-dynactin perinuclear localization important for nucleus-centrosome coupling that occur upon meiotic progression of primary spermatocytes (PubMed:19357193, PubMed:23904267).  Plays a role in sperm motility and fertility (PubMed:19357193).  May have a role in the PNG/PLU/GNU pathway (PubMed:15737938).
What are the official names of this protein?
Protein asunder, Cell cycle regulator Mat89Bb, Integrator complex subunit 13, Maternal transcript 89Bb, Set apart in position or space protein.
What is the protein family that this protein belongs to?
Belongs to the asunder family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Colocalizes with dynein-dynactin on the nuclear surface at the meiotic G2/prophase transition in primary spermatocytes (PubMed:19357193). Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M (PubMed:23904267).
Protein: RL33_METI4
Sequence: MPREQIILECTEAKALGKPASRYYGTKNKKQQQGKIELRKYNPFLRRHTLHREIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ACPS_RHIL3
Sequence: MIIGIGSDLIDIRRVEKSIERFGERFTHRCFTEIERARSDKRANRAASYAKRFAAKEACSKALGTGIAQGVFWKDMGVVNLRSGKPTMLLSGGAALILESLLPAGHRPAIHLTITDDYPLAQAFVIIEALPESL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTBP2_HUMAN
Sequence: MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ
What is the function of this protein?
Isoform 2 probably acts as a scaffold for specialized synapses.
What are the official names of this protein?
C-terminal-binding protein 2, CtBP2.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
What are the subcellular locations of this protein?
Nucleus. Synapse.
Protein: HYAL2_SHEEP
Sequence: MWTGLGPAVTLALVLVVAWATELKPTAPPIFTGRPFVVAWDVPTQDCGPRHKMPLDPKDMKAFDVQASPNEGFVNQNITIFYRDRLGMYPHFNSVGRSVHGGVPQNGSLWVHLEMLKGHVEHYIRTQEPAGLAVIDWEDWRPVWVRNWQDKDVYRRLSRQLVASHHPDWPPERIVKEAQYEFEFAARQFMLETLRFVKAFRPRHLWGFYLFPDCYNHDYVQNWETYTGRCPDVEVSRNDQLSWLWAESTALFPSVYLEETLASSTHGRNFVSFRVQEALRVADVHHANHALPVYVFTRPTYSRGLTGLSEMDLISTIGESAALGAAGVILWGDAGFTTSNETCRRLKDYLTRSLVPYVVNVSWAAQYCSWAQCHGHGRCVRRDPNAHTFLHLSASSFRLVPSHAPDEPRLRPEGELSWADRNHLQTHFRCQCYLGWGGEQCQWDRRRAAGGASGAWAGSHLTGLLAVAVLAFTWTS
What is the function of this protein?
Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides.  Displays very low levels of activity.  Associates with and negatively regulates MST1R (By similarity).
What are the official names of this protein?
Hyaluronidase-2, Hyal-2, Hyaluronoglucosaminidase-2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: FLID_SALTY
Sequence: MASISSLGVGSNLPLDQLLTDLTKNEKGRLTPITKQQSANSAKLTAYGTLKSALEKFQTANTALNKADLFKSTVASSTTEDLKVSTTAGAAAGTYKINVTQLAAAQSLATKTTFATTKEQLGDTSVTSRTIKIEQPGRKEPLEIKLDKGDTSMEAIRDAINDADSGIAASIVKVKENEFQLVLTANSGTDNTMKITVEGDTKLNDLLAYDSTTNTGNMQELVKAENAKLNVNGIDIERQSNTVTDAPQGITLTLTKKVTDATVTVTKDDTKAKEAIKSWVDAYNSLVDTFSSLTKYTAVEPGEEASDKNGALLGDSVVRTIQTGIRAQFANSGSNSAFKTMAEIGITQDGTSGKLKIDDDKLTKVLKDNTAAARELLVGDGKETGITTKIATEVKSYLADDGIIDNAQDNVNATLKSLTKQYLSVSNSIDETVARYKAQFTQLDTMMSKLNNTSSYLTQQFTAMNKS
What is the function of this protein?
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament.  Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
What are the official names of this protein?
Flagellar hook-associated protein 2, HAP2, Filament cap protein, Flagellar cap protein.
What is the protein family that this protein belongs to?
Belongs to the FliD family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RUTB_ECOBD
Sequence: MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFAHIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: RNC_ACICP
Sequence: MIKHQFKLSDPRLLSRIGYQFKQLELLQLALTHRSVSHKYNYERLEFLGDSLLGMIIANYLYHAYPNENEGRLTRMRATLVRQEALGKIATDLQLSRCLILSTGELKSGGHHRESILADTVEAIIGAIYLDSGDLNLLKDIVLKWYIPYLDHIEPTDQLKDPKSRLQEYLQARKKPLPVYEVVDIQGDAPHQHFKVECVVDGLPKIYGEGSSRRFAEQAAAAEILKLLEQ
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_CORDI
Sequence: MTNVIKYLAEGEALPLEDHPSVLLPASYDIVWSLVVFIIVLILFWKFVRPKYQEVLTEREDRIKGGIQRAEAAQAEAKAALEKYNAQLAEARAEAAEIREEARAKGKQIEAEMKAKATEESNRIIESGEKQLAAQREQVVTELRREMGQNSISLAERLLGDQLSDDVKRSGTIDKFLAELDTVSPAGK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PYRD_ALISL
Sequence: MLYRIARAGIFKLDAEKAHDLAIQNFKRFNGTPLDIFYRQKLVSKPVEVMGIQFKNPIGLAAGLEKNGECIEAFGAMGFGFIEVGTVTPRPQAGNDKPRLFRLIEAEGIINRMGFNNLGVDNLVENVKKAKYDGVIGINIGKNKDTPIEKGTEDYLICMEKVYQYAGYIAINISSPNTPGLRTLQYGEALDDLLSQLKEKQKELAEKYGKYVPIALKIAPDLDDNELSQIADSLMKYKIDGVIATNTTLDRSMVEGMKHAEEMGGLSGRPIQTRSTEVVRRLKELLGDSLPIIGVGGVDSYVAAKEKMVAGADLVQVYSGFIYKGPNLIRDIVNNI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.