PharMolix/UniProtQA huggingface dataset:
Protein: ATPB2_NITEC
Sequence: MSGMGEKSEQISKSARSTDPQEQESVALASQCVGEGRVLKIRGGVVDVFFTEHIPRIHDLVYAGDLAMEVAALLDQGTVRCIALTPVRGLGLGMPVHATGAPIQVPVGEAVLGRMLNVFGEPIDGKPAPNATISRSIHQAPPVLEERVVHSTILETGIKAIDLLSPIERGGKTGLFGGAGVGKTVLITELINNTAQHHKGVSLFCGIGERSREAEELYREMGEAGVRDKTVMLFGQMSEAPGVRFLVGKTALTMAEYFRDDLGQDVLLLIDNVFRFVQAGSEVSGLLGRMPSRVGYQPTLATELASLQERITSTRKGAITSIQAVYVPADDFTDPAAAHIFSHLSASVVLSRKRASEGLYPAVDPLASTSVMLTPAVVGQRHYDIARAVRRTLAEYEELRDIIAMLGLEELSAADRTVVARARRLERFLTQPFFSAESFSGEIGARVSVAETLAGCERILQQTKFADDEIDYYMIGALPEQKTAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: STK3_RAT
Sequence: MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDVQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIKNAKPVSILRELITEGMEIKAKRHEEQQRELEDEEENSDEDELDSHTMVKTSSEGVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCDQSMREPCPMSNNVFPDNWRVPQDGDFDFLKNLSLEELQMRLKALDPMMEREIEELHQRYSAKRQPILDAMDAKKRRQQNF
What is the function of this protein?
Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation.  Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.  STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation (By similarity).  Phosphorylates NKX2-1.  Phosphorylates NEK2 and plays a role in centrosome disjunction by regulating the localization of NEK2 to centrosomes, and its ability to phosphorylate CROCC and CEP250.  In conjunction with SAV1, activates the transcriptional activity of ESR1 through the modulation of its phosphorylation.  Positively regulates RAF1 activation via suppression of the inhibitory phosphorylation of RAF1 on 'Ser-259'.  Phosphorylates MOBKL1A and RASSF2.  Phosphorylates MOBKL1B on 'Thr-74'.  Acts cooperatively with MOBKL1B to activate STK38 (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase 3, Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The caspase-cleaved form cycles between nucleus and cytoplasm (By similarity). Phosphorylation at Thr- 117 leads to inhibition of nuclear translocation (By similarity).
Protein: YPE4_NPVLD
Sequence: MINEVCADAALGRHEARRDRELRTLQSQLYEVCRRSGVADSFCSSLMMSPVGVGGATSKPYFKGGVEEDRVQSSLRRNDVLVVPARVP
What are the official names of this protein?
Uncharacterized 9.7 kDa protein in PE 3'region, ORF 4.
Protein: CACP_YEAST
Sequence: MRICHSRTLSNLKDLPITSRRAMHSAIVNYSTQKAQFPVETNNGEHYWAEKPNKFYQNKRPNFQGITFAKQQDLPSLPVPELKSTLDKYLQTIRPFCNDVETFERQQLLCKDFSEHMGPILQDRLKEYANDKRNWMAKFWDEQSYLQYNDPIVPYVSYFYSHMPLPNHLSKIDNDPLIKATAIISTVVKFIEAIKDESLPVEIIKGMPFCMNSFSLMFNTSRLPGKPEDNQDTNIFYSVYENNFVTIAYKGKFYKLMTHDGNDKPLSENEIWRQLYSVVFQGSQSDPKLGGIGSLTSLPRDQWREVHLELMKDPISQDSLETIHKSSFMLCLDLDQSPVTLEEKSRNCWHGDGINRFYDKSLQFLVTGNGSSGFLAEHSKMDGTPTLFLNNYVCQQLNKLDVDDFMRKVITPSSTVAMKPMELPFIITPKIHKAIESAQLQFKETIGEHDLRVWHYNKYGKTFIKRHGMSPDAFIQQVIQLAVFKYLKRQLPTYEAASTRKYFKGRTETGRSVSTASLEFVSKWQNGDVPIAEKIQALKHSAKEHSTYLKNAANGNGVDRHFFGLKNMLKSNDDQIPPLFKDPLFNYSSTWLISTSQLSSEYFDGYGWSQVNDNGFGLAYMLNNEWLHINIVNKPAKSGASVNRLHYYLSQAADEIFDALENENKRKAKL
What is the function of this protein?
Carnitine acetylase is specific for short chain fatty acids.  Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex.  It may be involved as well in the transport of acetyl-CoA into mitochondria.
What are the official names of this protein?
Carnitine O-acetyltransferase, mitochondrial, Carnitine acetylase.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. SUBCELLULAR LOCATION: [Isoform Peroxisomal]: Peroxisome.
Protein: CLPX_LEGPH
Sequence: MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQQHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSNILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAALIDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESVVNGLSKPILIYEQDEKKSASGSKD
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: UP05_LONON
Sequence: VGEAFWSAEEQK
What are the official names of this protein?
Unknown protein 5.
Protein: YCF12_PINKO
Sequence: MDLEVIAQLTVLTLMVVSGPLVIVLSAIRKGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y1870_SULIA
Sequence: MSAPNSYDDEELEELLRRKAAQEQKRLEEERKRKAELESQKESILRVILTPEARQRLTNIKLVKPEFAESLENQLIALAQSGRIKVPLTDEELKQILEQISEQNRRDFKIQIRERGWK
What are the official names of this protein?
DNA-binding protein M1627_1870.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: GPDA_STAAW
Sequence: MTKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCHTNKKYLKYAKLDVNIIATSDMTKAIQFADIYLMALPTKAMREVASQINDKLTSKKTFIHVAKGIENGTFKRVSEMIEDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKSVSKLTQDLFMNDYLRVYTNDDLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTRGLAEISRLGEKLGADPMTFLGLGGIGDLIVTCTSTHSRNFTLGYKLGQGESMDQALSEMNMVVEGIYTTKSVYHLAKEKNVDMPITNALYRVLFENISVKECVKDLMERDKKSE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_PSEAE
Sequence: MSKSLQAIRGMNDILPEQTPAWRYLERTFAGLLDGYGYSEIRLPILEFTELFARGIGEGTDVVDKEMYTFLDRNGESLTMRPEGTAGCVRAVLEHGLSGGGQVQKLWYTGPMFRYEKPQKGRYRQFHQIGVEVFNLPGPDIDAELIILTWRLWQKLGMADAVTLQLNTLGSSEARARYREALVAYLQERFEQLDEDSQRRMTTNPLRILDSKVESTQALLVGAPTLHDYLDEESIAHFEGLKARLDAVGLRYEINQKLVRGLDYYCRTAFEWVTDKLGAQGTVCGGGRYDGLVSQFGGKPTPGVGFAMGVERLVLLLETLGVIPAELNRPADLYVCAFGEPAELAALTLAEQLRSAIPGIRLLVNAGAGSFKSQFKKADKSGARFALILGEDEVANRVVGFKPLRDEGEQQSIAWDALPEHLAACLAQA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSR3_METST
Sequence: MMKIVIYHSNECDPKRCTSIKLQKQNKVAITHNMRKIPYNAIVLDAEADKAVSREDREKITKYGLSALDCSWKKLKKSSFNFKSKKNHRLLPFLVAANPVNYGKPCILSSAEALSAALYIVGYKDEARDLMNSFKWGPHFITLNENLLEAYSEAKNSTEIVEVQNEFLGGK
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
What are the official names of this protein?
16S rRNA aminocarboxypropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASR_SALTY
Sequence: MKKVLALVVAAAMGLSSAAFAAETATPAKTAAPAKTTQTTQHHKKQHKKTVEQKAQAAKKHQKKGGKAPAKTTSKPTTQPAA
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ASTB_ECOUT
Sequence: MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQGLLKMKKLADAGFPQAVIPPHERPFIPVLRQLGFRGSDEQVLEKVARQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVFVSDAVSTYLFNSQLLSRDDGSMVLVLPQECREHAGVWRYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFNALNDWVDRYYRDRLTAADLADPQLLREGREALDTLTQLLDLGSVYPFQREGGGNG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: FETP_NITEU
Sequence: MVRSVKCIRLGCEAEGLDFPPYPGELGKRIFDNVSKEAWSQWIKHQTMLVNEMRLNLADIKARKYLASQMEAYFFGEGADQPAGYIPPDK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: INTU_XENTR
Sequence: MDYTRGVSVEAAEEEEERRGWDSHSAGTCSSSYTDCSSCCSSDLEPEWLDRVQKNGELFYLELSEGEEEILLPLSPLEPVGVNHVRFNDSEAEILSEERKNVGKNSEPRFRKLAKMLKKKHTSKKGSAGLNGPTCPTSILKQHSSQKAGIIVRYQYRDTCLYVNPDRLPEGEPKEKSNLLQALIGIVHQSSRNSKRIERQGSQEASQRLSNQEKLVVHGFIPGSPAIRCGQILIGDTLVAVNDVEVHVENIERVLSCIPGPTQVKLTFETPVLCSGTALQNQSTQVQTSINDLAALVWGDEHANSQQDLQRMSHIVMYLTLRLDSDTSKEEQEIIYQYPVSEASHKLKSIRGLFLTLSDMLQNVTGAPIISSSLILNDELVHVSYWKENDKLLLISVPAQRFPLLQLKNMTADIVRTLKFMYSTLDRAFCQAENISRLDHFFSLFFQRALRVFSLTGIAGYGSQFYDACSSLLVENLPGVRWLSLPEDIKMEIDTVLSDLEALDFAELSEDFYEMRRLYMIIGTCLFYKGYLLSNHLPKEDLVDVAIYCRQYCLLTLASERIGQLIIWREVYPQYHLKQCGSSATEECTEPGGRYFLLIVGLRHFMLCTLLEAGGCTSKATGHPGPDYIYVDQVKATLLQLEMLDMSIEDRLSSAPNPCLSCADWFLPSTRDKLGNFTNSAVLSKLQTPPKKAPSPVSKRRLFAEAASSLRTRRPSPTRSSGGSDSGTDGAGESVGVVTHSTPDMARKFGRRESLGSGGSDGSGGSGSLLKINKKKYSLPNPFSSGSLRKNLSERETDDIYNTIKLTSGPENTLFHYLYFETLQGVFISPTHKEVEQLGGSIHPQLIKNFHRCCLSIHSVFQQALNQKNSKQSDSVACMDVAGFGPIKEHGVLFECSPENWNDQKKSPPTMSYWVVGRLFMQPQPQELYVCFHDSVTEISVELAFKLSFGMPL
What is the function of this protein?
Plays a role in the definition of cell polarity via the planar cell polarity (PCP) cascade.  Required for ciliogenesis by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules.  Proposed to function as core component of a functional module called CPLANE (ciliogenesis and planar polarity effectors) involved in recruitment of peripheral IFT-A proteins to basal bodies.  Controls the localization of both rhoa and disheveled in multi-ciliated cells.  Has an indirect effect on hedgehog signaling (By similarity).
What are the official names of this protein?
Protein inturned, Inturned planar cell polarity effector homolog.
What is the protein family that this protein belongs to?
Belongs to the inturned family.
What are the subcellular locations of this protein?
Cytoplasm. Cell surface. Cytoplasm, cytoskeleton, cilium basal body. Note=Enriched at the apical surface in ciliated cells.
Protein: DAPD_DINSH
Sequence: MSNAQLETAIEAAWEARDTISPATTGETREAIEETLNALDSGALRVAERGADGSWHVNQWAKKAVLLGFRIKDMEAQSGGPQGGGWWDKVDSKFLGWNSGAWEKAGFRAVPSCVVRKSAYIAPGVVLMPSFVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRETGEVMYGEVPPYSVVVAGSMPSKNGVNLYCAVIVKRVDERTRSKTGINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR11_SCHPO
Sequence: MAATTASCISFSQFQRLKKLIDSPASKHKPMEFKGTSKDDLEDDLNSFFDCEEELFLSANKIFYSKLRVYQTVRHWSLKQNWSSMSLDQKRNFILHCHHELSSGELLRNSALYSILYIAAGAYDSVGSFEEHVHSISENVYLLREFDIPKTVYSLFIEWNRTRKHSFLDNSRDEGFLNLLLSLMFFFLTLNNTDKTWIHSIRSLNPPVLPTLVKLFIDITSDYQLNLDKVIHSSLKKLSFLIFKVCIRLWGSQSYLQEKKAGLAEVLNISTSQQKPKTTALDYEVFRHEMATKFSSFADSYYPVPLDREQAHILPTLNTDSFHKSSFISSTRLCSPENPSLLVNTAKTSKMSARREQFQTNQNLPFCFTPNLEKLTIPYSVTEAANVFQNKTKRTLAVEQLLSERELLRRFTLQQRLVADLHEFYNSVKGPAHSFETEDPVLKFVSQSYDDLFPYMDNFIQLAVQLFYHISKKVNCLYVEAFSSSDAVLQRIQDNAVVDSPTEELSEQAARNRKSNVKIEYTEDFATGFAISGEISHSINNLEFVLYSLSSLFLMMLKWFRLSHVLRFERLAFLLYENHFLEIFNRHLTEGDCNRNTEKDVKCVRGGFFSYSSKMYKYDRVSIPVITRASSSRNLLITMNCLRVLEKVCKYSNIRKEIIARSNLHENLKKLLAIPHDKLRLYALKVLKLSVPFLGLKWKQANMSIITQIYLNCSLDLRDSWMFHENGSDTYRSAQLQETFLAILIRFYHIRLYGKKCKSLYQFCILEEMRLKKSIEELAASNMMEYIPESLWSYSFERSDTGFFENEFAAMHINDIA
What is the function of this protein?
Participates in the control of the reentry into the cell cycle following pheromone treatment.
What are the official names of this protein?
Factor arrest protein 11.
What is the protein family that this protein belongs to?
Belongs to the FAR11 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: GRP33_ARTSA
Sequence: MAAKPEQEPVYVRDLVKDYDDARQMLTQAGVSEAVLGTIDAEIKHIKTGSRPKTVPNTDGSGFMDLYNDTKVKLVSRCCLPVDQFPKYNFLGKLLGPGGSTMKQLQDETMTKISILGRGSMRDRNKEEELRNSGDVKYAHLNEQLHIEIISIASPAEAHARMAYALTEIKKYITPEEDPNYMMMAGHGAGPMMGMGGMMGGPGPMGPQGRGRGRGRGGFSGPDRTFDLLEKARMNTSETMDPGYGFDESYCGMGGGYEMPYNGNAGWTASPGRGAGAGARGARGGLDQSRGGGKFPSARGGRGRAAPY
What are the official names of this protein?
Glycine-rich protein GRP33.
Protein: PG051_VACCW
Sequence: MTLVMGSCCGRFCDAKNKNKKEDVEEGREGCYNYKNLNDLDESEARVEFGPLYMINEEKSDINTLDIKRRYRHTIESVYF
What are the official names of this protein?
Protein OPG051, Protein F7.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG051 family.
Protein: K2C73_BOVIN
Sequence: MSRQFTYKSGAAAKGAFSGCSVVLSGSSSPSYRAGSKGLSGGFGSRSLYSLGCARSVSFNMASGSGRAGGYGFSRGRASGFAGSMFGSVALGPMCPSLCPPGGIHQVIVNKSLLAPLNVELDPEIQKVCAQEREQIKALNNKFASFIDKVRFLEQQNQVLGTKWELLQQQDLDNCKNNLEPILEGYISNLRKQLEMLSGDRVRLDSELRSMRDVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYMSKVELQAKVDALEREIKFFTCLYEGEIAQMQSHISDTSVILSMDNNRNLDLNSIIAEVRAQYEDIALKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEIAELTRLIQRLRSETESVKKQCSNLETAITDAEQRGHCALKDAQAKLDELEAALLQAKEELARMMCEYQELMSTKLALDIEIATYRKLLEGEECRMSGEYTNSVSISVISSSMAGTAGTGAGFGYSGSGTYGYRPSSVGGGYGFLLGGCVTGSGNCSPRGEAKTRLGSTSEIKDLLGKTPALSSPTKKTPR
What is the function of this protein?
Has a role in hair formation.  Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity).
What are the official names of this protein?
Keratin, type II cytoskeletal 73, Cytokeratin-73, CK-73, Keratin-73, K73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: DCUP_DANRE
Sequence: MMDKDSFILPKDFPELRNDTFLRAARGEEIEHIPVWCMRQAGRYLPEFRESRAGKDFFETCRSPEACCELTLQPLRRFPFDAAIIFSDILVVPQAMGMEVQMCPGKGPTFPEPLKEPEDLQRLKTQVDVYSELDYVFKAITLTRHKIEGKVPLIGFTGAPWTLMSYMIEGGGSATHSKAKRWLYRYPEASHKLLSQLTDVIVEYLLGQVKAGAQALQVFESHTGCLGPVEFKEFSLPYLRDIARRVKDKIKESGLDNVPMIVFAKDGHYGLEDLSESAYEVVGLDWTIDPRSARVRTGGKVSLQGNMDPCALYGTKESISEIVRRMLEGFGTKGYIANLGHGLYPDMDPENVGAFVEAVHNHSRQLLKR
What is the function of this protein?
Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway.  Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme (By similarity).  In vitro also decarboxylates pentacarboxylate porphyrinogen I (PubMed:9806541).
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_BUCAT
Sequence: MNYFNTLNFTQKINQINKCRFMKKEEFNKKNDILKNKNIVIVGCGAQGLNQGLNMRDAGLNISYALKKNSIANKNQSWINAIENNFKVDDYDALIPDADLVINLTPDKQHHSVIKKLQKLMKKNAVLGYSHGFNIVEFGEKIRKDITVIMVAPKCPGTEVREEYKRGFGVPTLIAVHHENDINKIGLEVAKAWAFSTGGHRAGVLESSFIAEVKSDLMGEQTILCGMLQTASLLCYEKLITEKCNPAYSAKLIQNGWETITESLKHGGITLMMDRLSNSSKIRAYKLSKEIKKILSPLFQKHMDDIISGEFSNEMMKDWENQDLKLLNWRYKTKNTSFETAPVYNEKIPEQEYYDHGILMIAILKSGIELSFEKMIETGIKEESAYYESLHELPLIANTIARKKLYEMNKVISDTAEYGSYLFSESAYPILKEFISTLNKSDLGCALSHQSVNNIELYRINQKIQNHPIEIIGCTLRNYMKKMKAITVAK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: FABH_GLOVI
Sequence: MPAVQMTGVGGAVPAQVLTNYHLSELVTTSDEWIASRTGIRSRRILAPGQSLTQLAARAATDALSQAGRSPLDVDLLILATSTPDDLFGGAAHLQHEIGAVRAVAFDLTAACSGFVFALATASQFVRTGTYRTVLVVGADALSRYTDWTDRATCVLFGDGAGAALLEAGEVEGILGFELRTDGARAGHLNIHCTAEAVPLAADMAATRARFASITMNGREVYRFAVEAVPDLIEKTLAACGVAPEQVKAYLLHQANQRILDSVASRLHVAPERMASNLADYGNTSSASVPLILQEWVQDGRIRAGDRVVLAGFGAGLSWGVLLARWGRL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_LEUMM
Sequence: MTESTFKSGFVAIIGRPNVGKSTLLNRIVGEKIAIMSDKAQTTRNKIQGIYTTDDAQVVFIDTPGVHKPQNSLGDFMVKSAFSALHEADAIWFVVDASMARGRGDDFIIDRLQEVKNTPIYLLINKVDLLAPNDLLDVIASYQNDAPEWAEVFPISATEGDNVPELLDNIVSHLDEGPQYFDADQLTDHPERFVIGELIREKVLQLTRQEVPHSVAVVIDKIARENEEKIHIQASIIVERPTQKNIIIGKQGAMIKDIGTRARKDIERLLGDKVFLETWVKVEPRWRDRPQALQTLGYRQEDY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: SYT_HALH5
Sequence: MADMINITFPDGAVKEFPKGTTTAEIAGSISPGLKKKALAGMLDGTLLDLNTPIEQDGTITIVTPESDEALEVLRHSTAHVMAQALKRLFKDRNVKLGVGPVIEGGFYYDVDMDESLTPEDLPKIEKEMKKIIGENLPIERVVVSREEALARYEEVGDPYKIELINDLPEDETITIYEQGEFFDLCRGVHVPSTGKLKEFKLLNLAGAYWRGDSSNKMLQRIYGTAFFKKADLDEHLRLLEEAKERDHRKLGKELGIFALSQKVGQGLPLWLPKGATIRRIIERYIVDKEEKLGYQHVYTPVLASSELYKTSGHWDHYKDDMFPTMEMENEELVLRPMNCPHHMMVYKTEMRSYRQLPLRIAELGLMHRYEMSGAVSGLQRVRGMTLNDAHIFCRPDQIKDEFVRVVRLIQAVYEDFGLKNYSFRLSYRDPEDKEKYFDDDNMWNKAQGMLKEAMDELELEYFEAEGEAAFYGPKLDVQVRTALGKDETLSTVQLDFLLPERFDLTYVGEDGQPHRPVVVHRGVVSTMERFVAFLLEEYKGAFPTWLAPVQVQVIPVSPEAHLEYAKNVQETLQQAGIRVEIDERDEKIGYKIREAQMQKIPYMLVLGDKEVEANGVNVRKYGEKDSSSMGLDEFVRHVAREAKK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: PGAM1_CHICK
Sequence: MAAYRLVLVRHGESAWNLENRFCGWYDADLSPAGQQEARRGGEALRDAGYEFDICFTSVQKRAIRTLWNVLDAIDQMWLPVVRTWRLNERHYGALTGLNKAETAAKHGEAQVKIWRRSFDIPPPPMQSDHPFFSTISKDRRYADLTEDQLPTCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGMSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate.  Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate.
What are the official names of this protein?
Phosphoglycerate mutase 1, BPG-dependent PGAM 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.