PharMolix/UniProtQA huggingface dataset:
Protein: X_WMHBV
Sequence: MAARLCCYLDPERDVLCLRPLQAEPSGRPFSGLSRPAETAAAAAVPAFHGAHLSLRGLPSCAFSSAGPCALRFTSATWRCMETPMNSVTCLRKRTLGLRTAPPTVMEQYIKDCLFEQWEEQGEEPRLKVFVLGGCRHKLVGTASPCIFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: SYK_HAEIN
Sequence: MSEQEVKELDLNGEMLVRREKLAALRAKGNAFPNKFRRDALAQDLHNQYDAEDGEILKEKGIEVQVAGRIMTRRAMGKATFITIQDMSGKIQLYVARDNLPEGVYKDDVGTWDLGDIVGIKGTLFKTKTDELTVKTTEVQLLTKALRPLPDKFHGLTDQEVRYRQRYLDLISNEESRRTFIIRSKVVAGIREYFISKGFMEVETPMLQVIPGGASARPFVTHHNALDVDMYLRIAPELYLKRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMLEYYQAYADYHDLMDNTEELLRKLAIDILGTTIVKYGDLEFDFGKPFERITLHDATIKYGADKGIVKEDLYDFDRAKATAERLGIEVQKSWGLGSIVNAIFEEVAEHHLIQPTFLNGSPAEISPLARRNDENPEVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEAMFKDEDFVVALEHGLPPTAGEGLGIDRLAMLYANAPSIRDVILFPAMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS7_CVFE3
Sequence: MLVFLHAVLVTALILLLIGRIQLLERLLLSHLLNLTTVSNVLGVPDSSLRVNCLQLLKPDCLDFNILHKVLAETRLLVVVLRVIFLVLLGFSCYTLLGALF
What is the function of this protein?
May function in the formation of membrane-bound replication complexes or in the assembly of the virus.
What are the official names of this protein?
Non-structural 7a protein, ns7a, 11 kDa protein, Accessory protein 7a.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns7/ns7a protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: YCP11_KLEPN
Sequence: MSLKLKTIKSTKWSALSSLTIIVLGFLQMVILSRILEPFEFGVLSIMTVVFLFTDMLADCGLSNAIIQKKNITLDELSALYWVNIFLGVFLFVVTIILSYEISSWMRLDRLSFLIQLTALVFIIMPHGQQYRALMQKELEFDILSKIESFSYLTGFCLTVIIGIITKNASCAVFGYLLTVSMRTVILSFVGRKYYHPTWKRSKLREIKKQLLFSFYLTLDSILNYINSSITTPIVARVLGAIYVGGYNLSFNVAVNPPSKISPIITRVLFPALSKIQDDKERLRINFFKLLHVISYINFPALLGLCIIAKDFVYLVFGEKWLFIVPTLQLLCIAGAMRMVANPIGSLLMAKAKMELSVRFNFVKIIIFIPVLYFSTIWNGMVGAAIGFLICQAINALLSYFFLLKPVLGNCIVDYINSFFIPFVHTLPMILLLLVCDIYIDKISLTFFILKIVIGGGVYILTIFISPNKLLAEMKGLFRQLLLKS
What are the official names of this protein?
Uncharacterized membrane protein in cps region, ORF11.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS10_ALTMD
Sequence: MPNQRIRIRLKAFDHKLIDQSTAEIVETAKRTGAQVSGPIPLPTRKERYTVLISPHVNKDARDQYEIRTHKRLVDIIEPTDKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RGS2_YEAST
Sequence: MASVPSLCDILIPLEKNSRSDGDAESSNTVLIQLRKGHHERMRSPYTIQKFYKFLKRAHCEENLEFFEKAHQFLQLKQNRSISEEKLLEVWNKSLYIKYIAVDSPKECNFSQDTREIFEKCFANNEVPADVDVLCAISHVMGLLMDGYHRFVSSVNEKKYSATYAHNDSATEQDLKNESTTSFSSLGVEDISEDRNSYLKKPDINGLSTIIQETSANTTNESQCSDRTSRPSESSSSLNTTSSTYKNTSTRNLQKPQNTGILNSGKGLLQKLNFVKKRKSFKQPSGVICSHYNSNVQNRLKGQNSHQQR
What is the function of this protein?
GTPase activating protein for GPA2.  Negatively down-regulates glucose-induced cAMP signaling via GPA2.
What are the official names of this protein?
Regulator of G-protein signaling 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NANK_CITK8
Sequence: MSTLAIDIGGTKLAAARVDDDLRIRERRELPTPASKTPDALREALKVLVEPLQTTAQRVAIASTGIIREGALLAINPHNLGGLLHFPLVPTLEDLTGLPTLAVNDAQAAAWAEYHALASDVRDMVFITVSTGVGGGVVSDGRLLTGMSGLAGHLGHTLADPQGPVCGCGRRGCVEAIASGRGIAAAAQGSLAGCDARTVFAHAAAGNEQAVRLVQHSAQVVARLIADVKATTDCQQVVIGGSVGLAEGYLAQVRHFLAQEPAVYQVALSAAHYRHDAGLLGAALLAQGDK
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: CITD_ECO57
Sequence: MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDAIRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_THENN
Sequence: MRIGLLGFGKSNRALLDYLLENGEAEIFVSEEKRLDDDTKSYLRKCGVDFEEEGNTEKLLDCDVVYVSPGVKPRSDIVKKLLAGGVNISTELQFFLDRADKEKVIGITGTNGKSTSAALMHHALSHRGLKVFLGGNFGTPAVEALREDYDYYVLEVSSFQLFWCERPRVSRFVLLNISEDHLDWHSSFKEYLNSKLKPAFFQEEKDTFVYNKNIETLEDLSRVKPKKIPFWTEDTFVEENRLVLQGKSFPLPGSYPLQMKENILAVSVLYNELFGDVEGFLDSLRSFKPLPHRMEFLGKIKGRSFYNDSKATSTHAVLGALSNFDRVILIMCGIGKNENYSVFIERARPRIKHLIVFGEIYRDLRPFLSNVPYSIVSDLEEAFRKALEVSEEGDVILFSPGGASFDMYENYAKRGEHFREIFERYKKEEGES
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DT3E_PSECI
Sequence: MNKVGMFYTYWSTEWMVDFPATAKRIAGLGFDLMEISLGEFHNLSDAKKRELKAVADDLGLTVMCCIGLKSEYDFASPDKSVRDAGTEYVKRLLDDCHLLGAPVFAGLTFCAWPQSPPLDMKDKRPYVDRAIESVRRVIKVAEDYGIIYALEVVNRFEQWLCNDAKEAIAFADAVDSPACKVQLDTFHMNIEETSFRDAILACKGKMGHFHLGEANRLPPGEGRLPWDEIFGALKEIGYDGTIVMEPFMRKGGSVSRAVGVWRDMSNGATDEEMDERARRSLQFVRDKLA
What is the function of this protein?
Catalyzes the epimerization of various ketoses at the C(3) position.  It is able to interconvert D-tagatose and D-ribulose to D-sorbose and D-xylulose, respectively.  The enzyme is also able to accept other ketopentoses such as D-psicose with lower efficiency.
What are the official names of this protein?
D-tagatose 3-epimerase, DTE, D-ribulose 3-epimerase, Ketose 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the hyi family.
Protein: CBAR2_BOVIN
Sequence: MNIILSRDSQVRVMEDTVTNAEKSFGQFCSLLAAYTRKTARLRDKADQLVKQLIDFANTENPEMRATLRNFAEDLAKVQDYRQAEVERLETKVINPLKLYGVQIKQTRAEIKKFKSVRNNEIKQLEKLEKLRQKSPSDRQTISQAETSVQRASVDASRTSHQLEETVDTFQKQKLKDIQKIFSDFVTIEMVFHAKAVEVYSSAFQTLESYDLEKDLEDFRAKMHGVYGRYDARPPLMDTTLSPALPWSLAQSAQSTIRSQRKEAVSEDDSAEEDPVEDLRGQAQRLNQ
What is the function of this protein?
May play a role in ciliogenesis.  In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis.
What are the official names of this protein?
CBY1-interacting BAR domain-containing protein 2, Protein FAM92B.
What is the protein family that this protein belongs to?
Belongs to the CIBAR family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Extensive colocalization with CBY1 at mother centrioles.
Protein: RL14_BACVZ
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKQATPGGVVKKGEVVRAVIVRTKSGARRTDGSYISFDENACVIIRDDKSPRGTRIFGPVARELRENNFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PDXT_STAAT
Sequence: MKIGVLALQGAVREHIRHIELSGHEGIAVKKVEQLEEIEGLILPGGESTTLRRLMNLYGFKEALQNSTLPMFGTCAGLIVLAQDIVGEEGYLNKLNITVQRNSFGRQVDSFETELDIKGIATDIEGVFIRAPHIEKVGQGVDILCKVNEKIVAVQQGKYLGVSFHPELTDDYRVTDYFINHIVKKA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SYR_SHESR
Sequence: MKSHIQSLLEQTIESFKQQGILPADFEARIQVDRTKDKSHGDLATNLAMMLTKAAGKNPRELAQLIIDNLPASAYVAKVEIAGPGFINFFIDDSALANQLQAAISDEHLGIKLPTPQTIVVDYSSPNLAKEMHVGHLRSTIIGDSVVRTLEFLGHKVIRQNHVGDWGTQFGMLLAYMEELRAQNGEQAQLELSDLETFYRAAKLRFDESAEFATRARQLVVELQSGDEYCNKLWREFNDISLSHCHEVYERLGVSLTRADVHGESAYNADLEQVVKDLDAQGLLTQSNGAKVVFQEEFRNKEGEALPVIIQKADGGYLYATTDLAAMRYRSSVLKADRVLYFVDLRQALHFQQVFSLAKLAKFVRNDMSLEHLGFGTMNGEDGRPFKTRTGGVVKLVDLLDEANTRALELVRSKNPDMDEATLAEIARVVGISAVKYADLSKNRTSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRATDIDLSQAKIVLEHEKEKDLGNKLAQFGEILSRVVDKGQPHVLCGYLYELAGAFSSFYEACPVLAADNDEQKHSRLLLSQLTANTLQKGLNLLGIETLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC1_XENTR
Sequence: MGDVEKGKKIFVQKCAQCHTVEKTGKHKTGPNLWGLFGRKTGQAPGFSYTDANKSKGIVWGEDTLFEYLENPKKYIPGTKMIFAGIKKKNERADLIAYLKKSTSE
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
What are the official names of this protein?
Cytochrome c, somatic.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: DEOC_DEIRA
Sequence: MSLASYIDHTLLKATATLADIRTLCEEAREHSFYAVCINPVFIPHARAWLEGSDVKVATVCGFPLGAISSEQKALEARLSAETGADEIDMVIHIGSALAGDWDAVEADVRAVRRAVPEQVLKVIIETCYLTDEQKRLATEVAVQGGADFVKTSTGFGTGGATVDDVRLMAEVIGGRAGLKAAGGVRTPADAQAMIEAGATRLGTSGGVGLVSGGENGAGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_CAMJR
Sequence: MGQKVNPIGLRLGINRNWESRWFPTKANLVENIGEDYKIRAFLKRKLYYAGISQILVERTAKKLRVTVVAARPGIIIGKKGSDVDNLRKELQDLIGKDVNINIKEERKAGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKAGAKGIKVSVSGRLGGAEMARTEWYLEGRVPLHTLRAKIDYGFAEARTTYGNIGVKVWIFKGEVLHKGMQPEKTEESAPAKKPRRTRRGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NADE_SACS2
Sequence: MHEYIRKSLTIDCEAVTNYIVERIREYLEFSNKKGGVIGVSGGVDSAVTATLLAKATDNFFILLMPSSSTPKIDLDDSFEMIKFLNAQNKYKLINIDEIVKSFSNKIETENKYIIGNIKARVRMIILYAYAQMLDYLVVGTGDKSELLLGYFTKYGDGGVDVLPIGDLYKTQVRMLGKCLGLPERIVTKPSSPALWEGQTAEGELGIDYETIDSILYLRFDEMRSEDEIVKMLGIPIDIVKKVDRLVKISQHKRLPPEIFRLSGRAINSDWRFPRRWA
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: YNFB_SHIF8
Sequence: MKITLSKRIGLLAFLLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: METK3_ATRNU
Sequence: MAAAVDTFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPESKVACETCTKTNLVMVFGEITTKANVDYEKIVRQTCRDIGFVSADVGLDADNCKVLVNIEQQSPDIAQGVHGHLTRRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNENGAMVPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIVAAGLARRCIVQISYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKESFDFRPGMIAINLDLLKGGSRYLKTAAYGHFGRDDADFTWETVKPLKWEKPQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate (By similarity).  May be involved in the synthesis of betain in response to abiotic stress such as high salinity (PubMed:15695433).
What are the official names of this protein?
S-adenosylmethionine synthase 3, AdoMet synthase 3, Methionine adenosyltransferase 3, MAT 3.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE7_HPV24
Sequence: MIGKEVTLQDIVLELTEPQTVDLHCEEELPEQDTEVEPERRAYKIILCCGGGCGTRLRLFVAATQFGIRGLQDLLLEEVVILCPDCRNSDLQHGGQ
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: FGF1_PONAB
Sequence: MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
What is the function of this protein?
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.  Functions as potent mitogen in vitro.  Acts as a ligand for FGFR1 and integrins.  Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades.  Binds to integrin ITGAV:ITGB3.  Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling.  Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1.  Can induce angiogenesis.
What are the official names of this protein?
Fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, HBGF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1. Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59 (By similarity).
Protein: RBPS2_CHICK
Sequence: MSNLNKDTEHTNGGGNVEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVTFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMATPNPTNIHPALGAHFIARDPYDLTGAALIPASPEAWAPYPLYTTELTPAIPHAAFTYPAAAAAAAALHAQMRWYPPSEATQQGWKSRQFC
What is the function of this protein?
RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (PubMed:22683258, PubMed:25064856).  Binds NOG mRNA, the major inhibitor of the bone morphogenetic protein (BMP) pathway (PubMed:25064856).  Mediates an increase of NOG mRNA levels, thereby contributing to the negative regulation of BMP signaling pathway and promoting reversible dedifferentiation and proliferation of smooth muscle cells (PubMed:25064856).
What are the official names of this protein?
RNA-binding protein with multiple splicing 2, Heart and RRM expressed sequence, Hermes.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_BORBU
Sequence: MEKKIALIAHDKKKEDLVNFVKQNYLFLSKFKLIATGTTGSKIQQATDLTIFKYKSGPMGGDQQIGAEVAEGNILAIFFFRDPLTSQPHEPDVSALIRLCDVHKIPLATNVKTAEILIKGLESLIF
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RS25_PYRAE
Sequence: MGGKKKPTLSQLAKKAEKEKAQQAQKAKKEVKKEETPAKRTIQVLDEKVFQAIAKEVQNMRVITPYEIASKYGIKMSVAFKVLRNLKERGDLVLVAKGHRTEIYVPAKRS
What are the official names of this protein?
30S ribosomal protein S25e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: ATPE_EXISA
Sequence: MNTVHVNVVTPDGAAFEGDARMVIAKSVTGELGILPKHIPMVTPLDVSVLKLRHEDGGRTLIAISGGFMEVRPDTVTILAETAEMADKIDYDRASAAKVRAERRLQDTKLSELEFRRAELALKKAINRLSIRDMKE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS18_KINRD
Sequence: MAKVPVRKPKKKQNPLKAAKIEAVDYKDTALLRKFISDRGKIRARRVTGVSVQEQRQIAKAIKNAREMALLPYSSSAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GMHA_ESCF3
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGMADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMAK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_CLOBA
Sequence: MANVLDELLDRGYIKQFTHEEETRKLLENEKVTFYIGFDPTADSLHVGHFIAMMFMAHMQRAGHRPIALLGGGTAMVGDPSGKTDMRKMLTKEQIQHNVDSIKKQMERFIDFSDDKALIVNNADWLLDLNYVDFLREVGVHFSVNRMLSAECFKQRLEKGLSFLEFNYMLMQGYDFYVLNQKYGCKMELGGDDQWSNMIAGVELVRRKAQGDAMAMTCTLLTNSQGQKMGKTVGGALWLDADKVSPFDFYQYWRNVDDADVEKCLALLTFLPMDEVRRLGALEGAEINGAKKILAFEVTKLVHGEEEAKKAEEAANALFSGGADMSNVPTVTIAKEDLGSTVLDIIAKTKIVPSKKEGRRLIEQGGLSINGEKIIDLTRTLNEDDFEDGSALIKRGKKNYNKIEIQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_STRP8
Sequence: MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSITTENAKIARYIYSFIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADSFFGLETGIEPQVLSDDNAGRSYLKGAFLTAGSIRDPESGKYQLEIYSVYLDHAQDLAQLMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDINRANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQVADALEFPITKSGVNHRLRKINKIADDL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.