PharMolix/UniProtQA huggingface dataset:
Protein: CDK9A_XENLA
Sequence: MAKNYDSVEFPYCDEVSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKVSPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNKYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITPEVWPNVDKYELYQKLELPKGQKRKVKDRLKAYVKDPHALDLIDKLLVLDPTQRLDSDDALNNDFFWSDPMPSDLKNMLSTHNQSMFEYLAPPRRRGGHMPQQPANQARNPAATNQSEFERVF
What is the function of this protein?
Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) and SUPT5H.
What are the official names of this protein?
Cyclin-dependent kinase 9-A, Cell division protein kinase 9-A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPRX1_HUMAN
Sequence: MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEGSSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
What is the function of this protein?
Transcription factor expressed after fertilization required for zygotic genome activation (ZGA), a critical event in early embryonic development during which the developmental control passes from maternally provided mRNAs to the expression of the zygotic genome after fertilization (PubMed:35314832, PubMed:36074823).  Binds and activates expression of key ZGA marker genes, such as NANOGNB, ZSCAN4, DUXB, KLF5 and DPPA3 (PubMed:36074823).  Binds to regulatory DNA sequences containing a 5'-TAATCC-3' sequence motif (PubMed:36074823).
What are the official names of this protein?
Tetra-peptide repeat homeobox protein 1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AVEN_HUMAN
Sequence: MQAERGARGGRGRRPGRGRPGGDRHSERPGAAAAVARGGGGGGGGDGGGRRGRGRGRGFRGARGGRGGGGAPRGSRREPGGWGAGASAPVEDDSDAETYGEENDEQGNYSKRKIVSNWDRYQDIEKEVNNESGESQRGTDFSVLLSSAGDSFSQFRFAEEKEWDSEASCPKQNSAFYVDSELLVRALQELPLCLRLNVAAELVQGTVPLEVPQVKPKRTDDGKGLGMQLKGPLGPGGRGPIFELKSVAAGCPVLLGKDNPSPGPSRDSQKPTSPLQSAGDHLEEELDLLLNLDAPIKEGDNILPDQTSQDLKSKEDGEVVQEEEVCAKPSVTEEKNMEPEQPSTSKNVTEEELEDWLDSMIS
What is the function of this protein?
Protects against apoptosis mediated by Apaf-1.
What are the official names of this protein?
Cell death regulator Aven.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Note=Associated with intracellular membranes.
Protein: EBNA3_EBVB9
Sequence: MDKDRPGPPALDDNMEEEVPSTSVVQEQVSAGDWENVLIELSDSSSEKEAEDAHLEPAQKGTKRKRVDHDAGGSAPARPMLPPQPDLPGREAILRRFPLDLRTLLQAIGAAATRIDTRAIDQFFGSQISNTEMYIMYAMAIRQAIRDRRRNPASRRDQAKWRLQTLAAGWPMGYQAYSSWMYSYTDHQTTPTFVHLQATLGCTGGRRCHVTFSAGTFKLPRCTPGDRQWLYVQSSVGNIVQSCNPRYSIFFDYMAIHRSLTKIWEEVLTPDQRVSFMEFLGFLQRTDLSYIKSFVSDALGTTSIQTPWIDDNPSTETAQAWNAGFLRGRAYGIDLLRTEGEHVEGATGETREESEDTESDGDDEDLPCIVSRGGPKVKRPPIFIRRLHRLLLMRAGKRTEQGKEVLEKARGSTYGTPRPPVPKPRPEVPQSDETATSHGSAQVPEPPTIHLAAQGMAYPLHEQHGMAPCPVAQAPPTPLPPVSPGDQLPGVFSDGRVACAPVPAPAGPIVRPWEPSLTQAAGQAFAPVRPQHMPVEPVPVPTVALERPVYPKPVRPAPPKIAMQGPGETSGIRRARERWRPAPWTPNPPRSPSQMSVRDRLARLRAEAQVKQASVEVQPPQLTQVSPQQPMEGPLVPEQQMFPGAPFSQVADVVRAPGVPAMQPQYFDLPLIQPISQGAPVAPLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFLPQQPMEGPLVPEQWMFPGAALSQSVRPGVAQSQYFDLPLTQPINHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDVVQHQLDALGYTLHGLNHPGVPVSPAVNQYHLSQAAFGLPIDEDESGEGSDTSEPCEALDLSIHGRPCPQAPEWPVQEEGGQDATEVLDLSIHGRPRPRTPEWPVQGEGGQNVTGPETRRVVVSAVVHMCQDDEFPDLQDPPDEA
What is the function of this protein?
Plays an essential role for activation and immortalization of human B-cells.  Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters.  Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.
What are the official names of this protein?
Epstein-Barr nuclear antigen 3, EBNA-3, EBV nuclear antigen 3, Epstein-Barr nuclear antigen 3A, EBNA-3A, EBV nuclear antigen 3A.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae EBNA-3 family.
What are the subcellular locations of this protein?
Host nucleus matrix. Note=Associated with the nuclear matrix.
Protein: SYD_BUCBP
Sequence: MRTNFCGTLNVSHVGKTIKLCGWVNKFRNLKEILFIDIRDQTGIIQVLFSKKSELLFKKAADLRNEFCIQVLGIVQERITKNKNYTMSTGEIEIFALELKIFNKSQPLPIDLKSCNIEETRLKFRYLDLRHPNMIRNIIIRNDITIIIRNFMKKNKFLDIETPILTKSTPEGARDYIVPSRIHKNKYYALPQSPQLFKQLLMISGIDRYYQIAKCFRDEDLRSDRQPEFTQIDIEVSFLNAKKVRKIIERMITSVWNKIINVHLKKFQKLSFYDAIKMYGTDKPDLRNPIQLIDVTNIIHVKNNINAITLPNKKTQQNIVIAMCIPRGMSLNINYINSYHHLVQKYTKNKLFNVEVLNHCPIKEQKKTSFHKKPSSDLTFQLISKTSAKHGDMIFYLSEKSPLVYEIMGKLRIELGKDLNLIDYNSWKPLWITNFPLFKKNELNQYISTHHPFTAPKYMKIDTSITNYEEIVADSYDLVINGYEIGSGSVRIHDLELQKTVFNILGINTVLQKNNFNFFLNALKYGTPPHAGIALGLDRITMLLTNSHNLRDVIAFPKTTTGSCLTTGAPSKIIHF
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKH1B_AGRIP
Sequence: MNKIYFVIVFVACFCLFAEAQLTFTSSWGGGKRSGVAPMSCKNEEAVATIFKLIQNEAERFIICQQKS
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic prohormone type 1.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCG1_BOVIN
Sequence: MSQTKTLKVRVALLCILVGIVLALVAVVTDHWAVLSPHVEHHNSTCEAAHFGLWRICTKRIFVGDKERSCGPITLPGEKNCSYFRHFNPGESSEIFEVTTQKEYSISAAAIAIFSLGFIIVGTLCALLSFRKKRDYLLRPASMFYIFAGLCLSVSAEVMRQSVQRMVDSEHTAWIAHSLAWSFICACVAAALLLVGGLALLLLALPRMPRDPWESCMDAEPEH
What is the function of this protein?
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle.  Regulates channel inactivation kinetics.
What are the official names of this protein?
Voltage-dependent calcium channel gamma-1 subunit, Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Multi-pass membrane protein.
Protein: HIS1_CALS8
Sequence: MVTIALPKGRLTEEATELFQRSSLISIDISQETRKLVLEDPRGNLRFLMVKPFDVPTYVEYGIADMGIVGKDVLLEVNKKVYELLDLKIGKCFIALAGPKGLREELLKKPEKIIATKFPNITKEYFENVLGEDVQIIKLNGSVELAPILGLSDMIVDIVESGRTLRENGLEVYEKLYDISARLIINRASLKLKREIEGIVNCLERMILQ
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1449_MYCBO
Sequence: MLGDAQQLELGRCAPADIALTVAATVVSRQDCRSGLRRIVLDCGSKILGSDRPAWATGFGRLIDHADARIAALSEHHATVVWPDDAPLPPVGTRLRVIPNHVCLTTNLVDDVAVVRDATLIDRWKVAARGKNH
What are the official names of this protein?
Uncharacterized protein Mb1449.
Protein: CP2R1_HUMAN
Sequence: MWKLWRAEEGAAALGGALFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPDLKPRLGMTLQPQPYLICAERR
What is the function of this protein?
A cytochrome P450 monooxygenase involved in activation of vitamin D precursors.  Catalyzes hydroxylation at C-25 of both forms of vitamin D, vitamin D(2) and D(3) (calciol) (PubMed:12867411, PubMed:15465040, PubMed:18511070).  Can metabolize vitamin D analogs/prodrugs 1alpha-hydroxyvitamin D(2) (doxercalciferol) and 1alpha-hydroxyvitamin D(3) (alfacalcidol) forming 25-hydroxy derivatives (PubMed:15465040, PubMed:18511070).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:12867411, PubMed:15465040, PubMed:18511070).
What are the official names of this protein?
Vitamin D 25-hydroxylase, Cytochrome P450 2R1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: NOA1_HUMAN
Sequence: MLPARLPFRLLSLFLRGSAPTAARHGLREPLLERRCAAASSFQHSSSLGRELPYDPVDTEGFGEGGDMQERFLFPEYILDPEPQPTREKQLQELQQQQEEEERQRQQRREERRQQNLRARSREHPVVGHPDPALPPSGVNCSGCGAELHCQDAGVPGYLPREKFLRTAEADGGLARTVCQRCWLLSHHRRALRLQVSREQYLELVSAALRRPGPSLVLYMVDLLDLPDALLPDLPALVGPKQLIVLGNKVDLLPQDAPGYRQRLRERLWEDCARAGLLLAPGHQGPQRPVKDEPQDGENPNPPNWSRTVVRDVRLISAKTGYGVEELISALQRSWRYRGDVYLVGATNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNPTPYRMFKRHQRLKKDSTQAEEDLSEQEQNQLNVLKKHGYVVGRVGRTFLYSEEQKDNIPFEFDADSLAFDMENDPVMGTHKSTKQVELTAQDVKDAHWFYDTPGITKENCILNLLTEKEVNIVLPTQSIVPRTFVLKPGMVLFLGAIGRIDFLQGNQSAWFTVVASNILPVHITSLDRADALYQKHAGHTLLQIPMGGKERMAGFPPLVAEDIMLKEGLGASEAVADIKFSSAGWVSVTPNFKDRLHLRGYTPEGTVLTVRPPLLPYIVNIKGQRIKKSVAYKTKKPPSLMYNVRKKKGKINV
What is the function of this protein?
Involved in regulation of mitochondrial protein translation and respiration.  Plays a role in mitochondria-mediated cell death.  May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes.  Binds GTP.
What are the official names of this protein?
Nitric oxide-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. NOA1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RS17_PELTS
Sequence: MEGRGIRKTLTGRVVSNKMDKTVVVAVETLVRHPLYQRTIRRTKKFKAHDEENACRIGDKVKMMETRPLSKEKRWRVVEILERTKQI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PROB_RALPJ
Sequence: MALHSLIADARRLVVKVGSSLVTNDGRGLDQAAIARWAAQIAALRAAGKEVVLVSSGAIAEGMQRLGWAKRPKEIHELQAAAAVGQMGLAQVYESEFARHSIRTAQVLLTHGDLADRERYLNARSTLLTLLSLGVVPIINENDTVVTDEIKFGDNDTLGALVTNLIEGDALIILTDQRGLYTADPRKDPGARFVDEAQAGTPDLEQMAGGAGSSIGKGGMLTKILAAKRAAKSGAHTIIASGREADVLARLASGEAIGTQLRAPTGRMAARKQWMIDHLQLRGRVVLDAGAVEKLTAGGKSLLPIGVTEVQGEFARGEVISCVDAAGLEVARGLTNYSSAEARLIARKASSEIEAVLGYVSAAELVHRDNLVLL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND_DELAS
Sequence: MGALASHRVSDADFVAAIGVQWQHRPLAPEPGLAALLAQAQLDDGGKATVVQAVGMLVVDECVAHGYHSMDLVVLHPGTPGLDEALERFDKPHTHADDEVRYILEGEGLFGFFDAGGQERVLRVQPGDYLRIPAGVEHRFTLTATRRIKALRLFADTAGWVAQYTQRPAAAMEVPA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: IMB5_SCHPO
Sequence: MVESKIIKLLEQVQSADPNSRIQAELGLRDLEKYHDFAAKLTDIASSGASVPLRQGSLIYLQRYIVHHWSPLFEQFQDGPIPDENVKKHVRETLLHLLVSLDNFTLIKAVAYAVSLIANVDYPDEWPEVVPAVLHLLQSTNENSINASLDVLDELVDESLVEEQFFIIAPQLASILYQFIFSAPPNDSMRMLQARGIKLFRSCLELIEIYKETKAEHVRVFLEQILPPWMDMFSHKFEVSLVDDRQVILPDSCGYFCIMGEIAMTLTKLRELFPSKLTPYVVTFVELVWNIIEKLLDPYIREVVFSDGLDDSAFGDKYPIRYLVELLLFVSVALQSKFVQNLFVSNTVPVPPLPPCIPLLVQYTQLPKHQIEVYESDVSEYIANEFSMDFASDTVRGAAISVLSAFEEHTTLPIQQSLREMSATYILNNEINWIYQEALLYACCSVDAASDDTYDDYLDPIYEAIKVRIDYSDAPILLLSRFFLFIGYFSESTVVASQFFQIIMNNLVNALQVDTVQYAAMKAIERFCSVGKVKPILSLQPMILEVLSQYASKSSDEALVLLVEAISSAVKLDCAKAAELGNSVIPLLFNLVATNASDPYICGIIEDTFEDIIHAANNYESMCEITLPELLQVLNQEDPIMVNIGATLLSCLIRAGPSPLPNGFVGYVLPPVYKITQIHSGDTELLQLSQEILKGLLEKDTPQLLETEISGSSGFQYILFILHQLLDKESDDSACFLVGPILLELADHASQMVDLQSILLSCIKRLAIAEQPRFIQSIIYVFAKLIVKDSLGMMHFLTSSLLNEQGLTAFEVLMTVWCDNFVYFSNFKNISIICIAMTKIYSFDSPLLDSVQVKGELISHSNRIITRSQSKLHPEEYSYVSVGEKILRLLSEEFVSLSKDAIVEEVSDDGADDWDDGPISAETFGLSANDVNELSKDEFSGVDNSEDEDNTDLQFYLLEFFKEAMKSNLHNINEVVFRLPQEEQDALVQIKEK
What is the function of this protein?
Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.  Serves a receptor for nuclear localization signals.  Mediates the nuclear import of TATA-binding protein (TBP) and of histones H2A and H2B (By similarity).
What are the official names of this protein?
Importin subunit beta-5, 114 kDa karyopherin, Karyopherin subunit beta-5, Karyopherin-114.
Protein: ALG11_DEBHA
Sequence: MGYLVVIGVIACVAYGILQVVSTVLPRLLLVPSQNWQDKIKKEIEQPMVRYLKVGNKRSSYRRRLVLASKQPSFYTNFVNNKIKVASVDSQNDEGEFLAEMKKRDVRDPQRKIIYGFFHPYANNGGGGERVLWQAVQATLATSDRNIVAIYTTNYESDPTSILDKVEAKFQISRLDEDRIVFVYLRKYARLIDGDYWKRFTLIGQLFGSMVLSWEAMFELSPDVWIDTIGLPGSYLLVSLVLKIPIMSYVHYPIIQPEMFNKLKFQGLSQIRVPKLSEIKTDVFSIGKLIYWSGVFYFYKYLGSLVNITLANGSWTFNHISNIWTINKDEAGYEMDILYPPCGTETLTKNVETLGSRENKLLFIAQFRPEKRHSLILRQYSKFLVNATSIGTPLKNIPTLVFLGSCRTPDDTKTLHDLKQEVDDLELNGYVEFVVDCSYEDIMVWLSKVKFGLNAMWNEHFGIGVVEYMSRGVIPLCHASAGPLLDIVTNWDNEPTSVSWYNNTGFFFKDKSDPDFDLSLQSDTASEFLQFSSRDNKDSTSTYPTLARLLDELFITNPDLISETRLQSMRENGVKSVLEKFSNGVFTLKWMQYSNQLGDLEKSYREERRSGIEKVY
What is the function of this protein?
Required for N-linked oligosaccharide assembly.  Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).
What are the official names of this protein?
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Alpha-1,2-mannosyltransferase ALG11, Asparagine-linked glycosylation protein 11, Glycolipid 2-alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YAN6_SCHPO
Sequence: MNPSSSPNRSLNPTRGLNLYSTGNEVTWFSSTVDEVNELKPAKSKAFSISAQDQIYGTSSLKSRFSTHEASSEKDDSSDFTLVLPSNRMYIVIPGLMLSIFLSALDQTVITTAIPTIVANLDGGSSYSWIGTAYTLAQTSILPFCGIMSEVVGRKIVLYTSIVLFLFGSAMCGAAQNMLWLVLCRAVQGIGGGGITSLVTIVIADITPLQTRPYYTGCMGVTWGLASVMGPLIGGAISQKASWRWIFFINLPTGGLSLALLIFFLNLVPKPTVSFRVFLRDFDFVGIITITTGVVLFLVGLNIGSTTGHWAHANVLCYLIFGILCIAGFVVNEFYTTRTRIITPSAFKTLSLTSVMVTSFLHYYIVSTITYYIPVYFQNIKGDGPLMSGVHTLSLAVVSSLLSAVSGMGIGKLKNYRYPMIGGWIVLLAGTGSMIAIYYNTDISRTMGFLALTAVGTGNLFQPNLIAVQASVPPALIATSCSAFMLLRNMGASVGISMGAVIYDQQLTTLLKGTKYSAGLSYSQIASIPNVSEKNFVFNAYANAIRMIWIVNCPVAGVGMLLSFFTKQEKLSQSVTEYKEKDKGFKDAP
What are the official names of this protein?
Uncharacterized transporter C3H1.06c.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LPLT_SHIB3
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNLJ_PSET1
Sequence: MASSISEQINHLRSTLEQHSYNYYVLDTPSIPDAEYDRLLQQLSALETQHPELITADSPTQKVGGAALSKFEQVAHQVPMLSLDNAFSEDEFIAFNRRIKERLMSTEELTFCCEPKLDGLAVSIIYRDGVLVQAATRGDGLTGENVTQNVKTIRNVPLKLRGSDYPAELEVRGEVFMDNAGFEKFNIEAEKRGEKVFVNPRNAAAGSLRQLDSKITAKRPLMFYAYSTGLVADGSIAEDHYQQLEKLTDWGLPLCPETKLVEGPQAALAYYTDILTRRGELKYEIDGVVIKINQKALQERLGFVARAPRWAIAYKFPAQEEITKLLDVEFQVGRTGAITPVARLEPVFVGGVTVSNATLHNGDEIARLGVKVGDTVIIRRAGDVIPQITQVVLERRPDDARDIEFPVTCPICDSHVEKVEGEAVARCTGGLVCPAQRKQAIKHFASRKALDIDGLGDKIVDQLVDRELIKTPADLFILKQGHFESLERMGPKSAKNLVTALQDAKATTLAKFLYSLGIREAGEATTQNLANHFLTLENVINASIDSLTQVSDVGEIVATHVRSFFAEQHNLDVVNALVEQGINWPELTPPSAQEQPLAGLVYVLTGTLNTLNRNDAKARLQQLGAKVSGSVSAKTDALVAGEKAGSKLTKAQDLGIDVLTEEDLINLLEQHNG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RGN_MOUSE
Sequence: MSSIKVECVLRENYRCGESPVWEEASQSLLFVDIPSKIICRWDTVSNQVQRVAVDAPVSSVALRQLGGYVATIGTKFCALNWENQSVFVLAMVDEDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGSLYSLFPDHSVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYTVDAFDYDLQTGQISNRRIVYKMEKDEQIPDGMCIDAEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKDYSEMYVTCARDGLNAEGLLRQPDAGNIFKITGLGVKGIAPYSYAG
What is the function of this protein?
Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone.  Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis.  Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro).  Calcium-binding protein.  Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity).
What are the official names of this protein?
Regucalcin, RC, Gluconolactonase, GNL, Senescence marker protein 30, SMP-30.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_XANC8
Sequence: MNEFDRVRDYLTDLQDRICAAVEAIDGKARFAEDLWQRAEGGGGRTRILRDGAVFEQAGIGFSDVSGARLPPSASAHRPELAGATWRACGVSLVFHPHNPHIPTTHANVRYFRAERDGEMVAAWFGGGFDLTPFYPVDEDVMHWHRTAQALCAPFGEERYAAHKRWCDEYFFLRHRNETRGVGGLFFDDLGQDFERDFAYQRAVGDGFLDAYLPIVERRKDTPYGEAERAFQLYRRGRYVEFNLVYDRGTLFGLQSGGRAESILMSLPPQVRWEYGFQPQPGSAEARLADYLIPRDWLG
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNF93_HUMAN
Sequence: MGPLQFRDVAIEFSLEEWHCLDTAQRNLYRNVMLENYSNLVFLGIVVSKPDLIAHLEQGKKPLTMKRHEMVANPSVICSHFAQDLWPEQNIKDSFQKVILRRYEKRGHGNLQLIKRCESVDECKVHTGGYNGLNQCSTTTQSKVFQCDKYGKVFHKFSNSNRHNIRHTEKKPFKCIECGKAFNQFSTLITHKKIHTGEKPYICEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKHYKCEECGKAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVASSTLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIKHKKIHTREKPYKCEECGKAFHLSTHLTTHKILHTGEKPYRCRECGKAFNHSATLSSHKKIHSGEKPYECDKCGKAFISPSSLSRHEIIHTGEKP
What is the function of this protein?
Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305).  Not able to repress expression of all subtypes of L1 elements.  Binds to the 5' end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes.  Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs.  50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression (PubMed:25274305).
What are the official names of this protein?
Zinc finger protein 93, Zinc finger protein 505, Zinc finger protein HTF34.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YIDC_PSEPF
Sequence: MDIKRTILIVALAIVSYVMVLKWNQDYGQAALPTQNVASSTTTSGLPDTATGNNAAASDDIPRAASDTSAPAETPVAASKDLIQIKTDVLDLSIDPQGGDVAQLTLPLYPRRQDRPDVPFQLFDNGGERTYLAQSGLIGTNGPDANPAGRPIYSSEKKTYQLADGQDKLVVDLKFSKDGVNYIKRFTLKRGLYDVTVTYLIDNQSAQPWSGSMFAQLKRDASADPSSTTATGTATYLGAALWTSSEPYKKVSMKDMDKAQLKETVTGGWVAWLQHYFVTAWVAPKGENNIVQTRKDSKGNYIIGYTGPSLTAAPGAKVETSAVLYAGPKSQAVLKELSPGLELTVDYGILWFIAQPIFWLLQHIHSIVGNWGWSIIFLTMLIKGIFFPLSAASYKSMARMRAVAPKLAALKEQHGDDRQKMSQAMMELYKKEKINPLGGCLPILVQMPVFLSLYWVLLESVEMRQAPFMLWITDLSIKDPFFILPIIMGATMFIQQRLNPTPPDPMQAKVMKMMPIIFTFFFLWFPAGLVLYWVVNNCLSIAQQWYITRKIEAATKKAEA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.