PharMolix/UniProtQA huggingface dataset:
Protein: XERC_MYCTO
Sequence: MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids (By similarity).
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBB_SALCH
Sequence: MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLCIYERCALFGVMGAGLVGAIAPKTPLRYVAMVIWIYSAWRGLQLAYEHTMIQLHPSPFMTCDFMARFPDWLPLGKWLPQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAVVIAQAFKPKKRDLFGR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GAG_SIVSP
Sequence: MGARNSVLSGKKADELEKIRLRPGGKKRYQLKHIVWAANELDRFGLAESLLENKEGCQKILSVLAPLVPTGSENLKSLYNTVCVLWCIHAEEKVKHTEEAKQIVQRHLVVETGTADKMPATSRPTAPPSGKGGNYPVQQIGGNYTHLPLSPRTLNAWVKLIEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGEHQAAMQIIREIINEEAADWDLQHPQPGPIPPGQLREPRGSDIAGTTSTVDEQIQWMYRQQNPIPVGNIYRRWIQLGLQKCVRMYNPTNILDVKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGINPTLEEMLTACQGVGGPGQKARLMAEALKDALTQGPLPFAAVQQKGQRKIIKCWNCGKEGHSARQCRAPRRQGCWKCGKAGHVMAKCPERQAGFLGLGPWGKKPRNFPMAQMPQGLTPTAPPEDPAVDLLKNYMKMGRRQRENRERPYKEVTEDLLHLNSLFGEDQ
What is the function of this protein?
p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Matrix protein p17]: Virion. Host nucleus. Host cytoplasm. Host cell membrane; Lipid-anchor. Note=Following virus entry, the nuclear localization signal (NLS) of the matrix protein participates with Vpr to the nuclear localization of the viral genome. During virus production, the nuclear export activity of the matrix protein counteracts the NLS to maintain the Gag and Gag-Pol polyproteins in the cytoplasm, thereby directing unspliced RNA to the plasma membrane (By similarity). SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: GLOD5_DICDI
Sequence: MFIDRLDHLVLTVSDIEKTCNFYENILGMKVITFGKDNERKALTFGNQKINLHKKGAEFEPKALLPTAGSADLCFITITPLHEVITELFQKNITIEEGPCERTGALSKPILSVYIRDPDYNLIEISNYK
What are the official names of this protein?
Glyoxalase domain-containing protein 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: CASP2_SORBI
Sequence: MTSESATVIQMDDGRAPAPAAAGAAAAAAASSSYATAPTSISAAEPAAAPRKTTTVPFLLRSGAEGFRRCLAVIDFLLRVAAFGPTLAAAISTGTADERLSVFTNFFQFHARFDDFPAFTFFLVANAVAAGYLVLSLPFSVVVILRPNKATGGVRLLLLLCDVLIMALLTAAGAAAAAIVYVAHSGNRRANWVPICMQFHGFCQRTSGSVVATFLAVLVFIVLILMAACVIRRSK
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 2, SbCASP2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: SYW_RALSO
Sequence: MFPERVLSGMRPTGALHLGHYHGVLKNWVRLQAEYPCFFFVADWHALTTHYESPEVIEESVWEMLIDWLAAGVDPTQATLFIQSRVPEHAELFLLLSMGTPLGWLERVPTYKDQIEKLKEKDLSTYGFLGYPLLQAADILIYRAGFVPVGEDQVPHVEMTREVARRFNYLYGREPGFEQKALDAAKKLGGKRAKLYLELRTAHQERGEDDALEQARALLAESQSLSMGDRERLFGYLEGARKIILPEPQVLLTEASRMPGLDGQKMSKSYGNTIRMREDKASVEKKVRTMPTDPARVRRTDPGDPGKCPVWQLHQVYSDADTREWVQKGCRSAGIGCLECKQPVIDGILREQQPMLERAQKYMDDPSLLRAIIADGCDTAHKVTQETMREVREAMGLTYS
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFBG_SHIFL
Sequence: MATYNGECWIEEQLKSIIEQKDVDISIFISDDLSTDNTLNICEEFQLSYPSIINILPSVNKFGGAGKNFYRLIKDVDLENYDYICFSDQDDIWYKDKIKNAIDCLVFNNANCYSSNVIAYYPSGRKNLVDKAQSQTQFDYFFEAAGPGCTYVIKKETLIEFKKFIINNKNAAQDICLHDWFLYSFARTRNYSWYIDRKPTMLYRQHENNQVGANISFKAKYKRLGLVRNKWYRKEVTKIANALADDSFVNNQLGKGYIGNLILALSFWKLRRKKADKIYILLMLILNIF
What are the official names of this protein?
dTDP-rhamnosyl transferase RfbG.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: ISPG_SULDN
Sequence: MINRVKTKQIFVGNVAVGGDSPISVQSMTFSKTSDVFSTVEQIKRLHFAGCDIVRVAVPEMEDALALRAIKEQISLPLVADIHFNYRLALIAAEVVDCIRINPGNIGSRERVKEVVKACQERNIPIRIGVNAGSLEKEFLNKYGQTSEGMVASAEYNIKFLEDLGFDDIKISLKASDVQRTVDAYRMLRPKNNYPFHLGVTEAGTLFHATVKSSIGLGALLLDGIGDTMRVSITGELEEEINVARAILKDSGAAKDGLNIISCPTCGRIEADLVSAVGEIERRTTHIKAPLNVSVMGCVVNAIGEAAHADIAIAYGKGKGLVMVKGEVVANLDEHELVDRFVQEVEKMAKEF
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: ECFA1_OCEIH
Sequence: MSRKIVEFRNVSFRYDEEGPWVLKNCSFEIYEDEWLAIIGHNGSGKSTIAKLLNGLLFPQEGEIYIDGIKVDENSIWDIRKEVGMVFQNPDNQFVGATVQDDVAFGMENRGIPREIMKKRIDETLQAVRMQDYLLTEPHRLSGGQKQRVAIASVLAISPKILILDEATAMLDPVGRKEIMQTVNSIQDSQGLSLITITHDLKEITRADRVIVLNNGERWDEATPSQLFKRKDALREIGLDVPFVAHLSDAFRNNGITIEHSPLSHEQLLEELWTYHSKM
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: S31F3_MOUSE
Sequence: MMVPSFILWDVGSSVYTYGSLFIIALIIWHVRRSHRGLRLGPIKSCTKCFRRIKQKPSDRTLRVKKRTTKEETEKLQKLLSNMKRQGWLPQEGSVRRLLCSDPSCPICNAMALEIQQLLGVENKKTSSSLLRHSRSFSCLEALSPPKVLNDQSSELSKVLNGQSSELSKVLNGQSSELSKVLNDQSSELSKVLNDQSSELSSQHSKDISLPPKFMQSQSTDQKLTLSAPLSTGNTVLQCYHPAPQQQPEPQGSNAFQDVSGLSSSSMDEHGVPANQQKKRKKTKKLVSKNQAAPSEAEMENKMTFFSHWVNPEVKCDRPEESFAFYKSETGAKPKTGEPKKSSAKVRAEEPNLEKHAKDLKAKPLHAKRNI
What are the official names of this protein?
Protein SPATA31F3, Protein FAM205C.
What is the protein family that this protein belongs to?
Belongs to the SPATA31 family.
Protein: DNCH_PROM3
Sequence: MNPENWLLLRRVVRFGDTDAAGVMHFHQLFRWCHEAWEESLEQYGLTPAEIFPGSRKSEVTPEVALPIIHCQADFRRPIHSGDALAMELRPERLNPNSFQVHFEFRCEEQIAAHALIRHLAINAKTRHRCALPEGIDRWLEASGVGKIGSI
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: RS4_BLOPB
Sequence: MAKYLGPKLKLSRREGTDLFLKSGIRAIDSKCKLDQPPGQHNMRKSRFSDYGIQLREKQKVRRIYGILERQFSNYYKRAARIKGNTGENLLKLLESRLDNTVYRMGFGATRAEARQLVSHKSIMVENRIVNIASYQVVPNTVIKIHKKSHKQSRIRASLELSEQQREKLAWIEVDPIKLQGLFKRYPERSELSANIDEHLIIELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RNL1_PIG
Sequence: IPKNLTRAQWFTIQHIQPSPLQXNKAMNGVNXYT
What are the official names of this protein?
Ribonuclease PL1.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Lysosome.
Protein: CGOX_MYCTU
Sequence: MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.
What are the official names of this protein?
Coproporphyrinogen III oxidase.
What is the protein family that this protein belongs to?
Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHSD_PARDE
Sequence: MRYITPRKAAEGLGSAHEGTQHHWAMTVSAVALTVLTPLFMIVVARAIGLSQEQLLAYFGRPFPALITALFVIVGMVHFIKGTRIMIDDYFQGGTRKAAIIFSVIFGWAVIAAAVYALARMGLGAIVVL
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase hydrophobic membrane anchor subunit.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP2B1_YEAST
Sequence: MSKDLNSSRIKIIKPNDSYIKVDRKKDLTKYELENGKVISTKDRPIASVPAITGKIPSDEEVFDSKTGLPNHSFLREHFFHEGRLSKEQAIKILNMSTVALSKEPNLLKLKAPITICGDIHGQYYDLLKLFEVGGDPAEIDYLFLGDYVDRGAFSFECLIYLYSLKLNNLGRFWMLRGNHECKHLTSYFTFKNEMLHKYDMEVYDACCRSFNVLPLAALMNGQYFCVHGGISPELKSVEDVNKINRFREIPSRGLMCDLLWADPVENYDDARDGSEFDQSEDEFVPNSLRGCSFAFTFKASCKFLKANGLLSIIRAHEAQDAGYRMYKNNKVTGFPSLITMFSAPNYLDTYHNKAAVLKYEENVMNIRQFHMSPHPYWLPDFMDVFTWSLPFVGEKVTSMLVSILNICSEQELDPESEPKAAEETVKARANATKETGTPSDEKASSAILEDETRRKALRNKILAIAKVSRMFSVLREESEKVEYLKTMNAGVLPRGALARGTEGLNETLSTFEKARKEDLINEKLPPSLSEVEQEKIKYYEKILKGAEKKPQL
What is the function of this protein?
Calcium-dependent, calmodulin-stimulated protein phosphatase.  This subunit may have a role in the calmodulin activation of calcineurin.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2B catalytic subunit A1, Calcineurin A1, Calmodulin-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2B subfamily.
Protein: DNAK_FRATF
Sequence: MGKIIGIDLGTTNSCLAIMDGKTAKVIENAEGHRTTPSVVAYTDSGEILVGQAAKRQAVTNPDNTFFAIKRLIGRKYDDKAVQEDIKKKVPYAVIKADNGDAWVATKEGKKMAPPQVSAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGKIAGLEVKRIINEPTAAALAYGVDSKKGEQTVAVYDLGGGTFDISIIEIADVDGDNQIEVLSTNGDTFLGGEDFDLALMNYLIDEFKKEQGIDLHNDKLALQRVREAAEKAKVELSSAQQTDVNLPYITADATGPKHLNIKVTRAKFESLVSDLVMRSLEPCKKALEDAGLSKSDITEVLLVGGQTRMPLVQEKVKEFFGKEPRKDVNPDEAVAVGAAIQGGVLAGDVKDVLLLDVTPLSLGIETMGGVMTKLIERNTTIPTKKSQVFSTAEDNQPAVTIHVLQGEREMASANKSLGRFDLADIPPAPRGMPQIEVTFDIDANGILNVSAKDKATGKEQNIVIKSSSGLSEEDIEKMVQDAEANAEADKKFHDLVTARNTADNLIHSSRKAIQELGDKVTAAEKEKIEEACKELEAATKGDDKQAIEAKTKALEEAFAPIAQKAYAEQAQAAGAQGGAKAEEPKKEEDVVDADFEDVEDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ARGR_HAEIN
Sequence: MTENLTRAFKELLNQERFGSQSEIVDALKKQGFTGINQSKISRMLSKFGAVRTRNTKMEMVYCLPNELSVPNTSSPLKNLVLDVDHNAMLIVIKTTPGAAQLIARLLDSIGKSEGILGTIAGDDTIFVTPTNNKPIDELLQNIQRLFENTL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_EUCGG
Sequence: MVREKVRVSTRTLQWKCVESRADSKRLYYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRAKFEKIPHEYSTIVGIQESVHEILMNLKEIVLRSNLYGTRNASICVKGPGCVTAQDIILPTSVEIVDNTQYIANLTEPINLCIGLQIERNRGYHIKTPKNFQDGSYPIDAVFMPVRNANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHAEEENLHLENNQYKVTLPFFTFHDRLAKLRKTKKEIALKSIFIDQFELPPRTYNCLKRYNIHTLFDLLNKSQEDLMKMEYFRIEDVKQILDSLEIEKAFHNPFTEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPMT_PSEU2
Sequence: MKTDFWLQRWSAGQIGFHQSEVNQDLQQYWSSLSVAPGARVLVPLCGKSQDMSWLRGQGYHVVGAELSEAAVESYFTERGEQPQITSQGDFKVYAAPGIEIWCGDFFALTVRDIGHCAAFYDRAAMIALPADMRERYVRQLEALMPQACSGLLITLEYDQTLLEGPPFSVPRTWLQRVMSGNWEVTKVGGQDTLHSSPKALKAGLERMDEHVYVLERQSR
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINAL_SYNC1
Sequence: MSLNIAILTTGDELVNGEMSDTNTARIAQLLGSWGYIVRESRAIGDDEVEIETALKDMSGRRDVIISTGGLGPTDDDLTARIAARAFGRRLVLNEEALAQIRRFFAEKNKEMHPRNEKQALLPQKTVILPNRLGTAPGFHLCHEQCDMFFLPGVPREMVDMLKEQVLPRLHERSGGQAPRQERILKVFGLSEPKVEEHFSQAPLPEGVELAFGVEFPFVYVKLRACGDQAGALLDRAEMHTRKVLQPFVFAVGQETLAGNVARMLTDTGLTLALAESCTGGMISQMLTDIPGASRFLERGGVTYSNAAKQDWLQVSEDILNQEGAVSKACAQAMAQGIRQAAGTDLGLAITGIAGPDGGTPDKPVGTVFLALSTTGEERVQGYRFSGDREQIRHISACMALEWLRRYLGNLY
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: METK_HELPS
Sequence: MKDSFLFTSESVTEGHPDKMADQISDAVLDYIIERDQKAKVACETLVANGFCMITGELKTSVYAPMQEIAREVVKKIGYTDALYGFDYRSAAVLNGVGEQSPDINQGVDREDGEIGAGDQGLMFGYACKETETLMPLPIHLAHQLTFALAQKRKDNTLPFLRPDGKSQVSVRYENNKPVSIDTIVISTQHSPEVSQKHLKESVIEEIVYKVLPKEYLHDNIKFFVNPTGKFVIGGPQGDAGLTGRKIIVDTYGGSCPHGGGAFSGKDPSKVDRSAAYAARYVAKNLVASGVCDKATVQLAYAIGVIEPVSVYVNTHNTSKYSSAELEKCVKSVFKLTPKGIIESLDLLRPIYSLTSAYGHFGRELEEFTWEKTNKAEEIQAFFKR
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLP2_RABIT
Sequence: MADSERLSAPGCWAACTTFSRTRKGILLLAEIILCLVILICFSAGTSGYSSLSVVEMVLAIVFFVIYMCDLHTRAPFINWPWSDFFRTLIAAILYLITSIFVLVERGNHSKIAAGVLGLLATCLFGYDAYFTFPLRQQRHTAAPTDPTDGPV
What is the function of this protein?
May play a role in cell differentiation in the intestinal epithelium.
What are the official names of this protein?
Proteolipid protein 2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SEC11_AJECH
Sequence: MLSSLSPYMANPRNTLSQVLNFGLVLSSAFMVWKTLSVITNSTSPVVVVLSGSMEPAFQRGDLLFLWNRSPRVDVGEIVVYNVQGKDIPIVHRVMRVFPDVPTTGGKDVESVEASQKLLTKGDNNLSDDTELYAPGQEFLDRKTDLMGSVRGYVPAIGYVTIMLSEHPWLKSVLLGFMGLMVMLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: VP33B_CAEEL
Sequence: MAPGTAELEIDETLHLLRMVMQREFIHYLETLPGTKELFIDKCLLRPLDMIATSSDMKRHGVKRIMHFDLQKSPQVWNIEIDQRVFFLRPNVENARKIVEYVEESSENRSICVIWCNRQLEECDLAFESSGVIGHITQLSLNMCLLPLESDLFSLQHVESAQPDLFSVANMFVALQNLYGVIPTVYGLGSESKNLWNLVHALCSSNELRARPDQPISHLFLFDRQLDPVPVLLTGASYEGLLHEFFTIDCGKLAFPVDLRKQVQTGPLDFDWIEINPEEDKEAHQQNRGDTVKLDNCEDIFASIRNKHVTAALEFLHSKAKSIQKSIEKSSMIDDVADYRNFVEKDLRALKKDHKHCELHINACEMMMNKVKMEDYRTMFKLEHEMLLGTVTHEEYFDFVFERVPMRSCRDVVLSMMSLASLKLDGVPDDTYNEFVEMYLQKYGYEHMFELQNLRNSRVIYARRHIAHDRTISERARTWETLARKFRIVKGNEPMDMSNPSDMSYVFGARISPLLCKIVEDTIDHGWNQAEYERIIGKDKVLVEENTYIAADRRPDNRTRKAIMVFVNGGITYWEVAALRLLAIQKNFRILICTTHVIKKREYLEVRAKDASSVFGS
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes (PubMed:25273556).  Believed to act as a component of the putative CORVET endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (PubMed:25273556).  The CORVET complex is proposed to function as a rab-5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25273556).  Most likely within the CORVET complex, it is involved in the fusion of endocytic compartments (PubMed:25273556).  Required for sperm development and function (PubMed:19109425, PubMed:27558849).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 33B.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Early endosome. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle. Recycling endosome.
Protein: CYB6_ORYSJ
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFSSVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPWDQIGYWAVKIVTGVPDAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AIM6_ASHGO
Sequence: MMLLSQPGIWLLVSLFLCSSVNSISLWKSHPLVAGSNEPDQKRPDTPSSPRPLGITGAALLNYFEQNLRTMEVPDTAGVPQDSAYYTALTHYLGLCGARSENCDPGQSAVAKLTRDVPVLTRVHSHNDYWRRVPLLQALAYGVASVEADVWLENNGTTLLVGHNRVFLEPAHDLGRLYIEPITRMLQEVNCKSENKGDPYGIFYNAPEEQLLLYIDFKSLDRKLTYKLLLDYLKPLIDNNFISYYDMDAKRFVSRPVTVVLTGNYPSDEEIGVPSPRRYTFLDAPLGRLSSVGDEFTANNVSVVASSSLLELMLRCGKASNPSLTEQTAWESYGCLVEYVREAHRRDLRARIWGLPDWPVSTRENLWDMLTDMGVDYLNVDDLDAVSKF
What are the official names of this protein?
Altered inheritance of mitochondria protein 6.
What is the protein family that this protein belongs to?
Belongs to the AIM6 family.
Protein: TRUD_PYRAE
Sequence: MLEAPSFDKMLGMFYYATDTCPSGGVIKRSPEDFVVEEVLLDGTVIATSGVELRPRVGNWTWIHVVKRNVDTIKLVLRLARALGLSHRDVSVGGLKDTKAVTSQIISVRGPVANLPQLPGVQFLGMWSMDKPITPSQIYGNRFTIILRDVERISCAEGALEALKKTAAPNYYGYQRFGTIRPVTHLLGKALLKKDPHLFFEVMFCKIFSRESEVAKRAREAACKGDYAKALELFPKKFVEERVFLKRLAGGYDMWNAIMAIPPQILRVYIEAAQSYIFNRFLSIRMEIGPIDRPVEGDLVEINRQIAYYAEGLGGEVVLPVVGAGVRMPRGKVGEALLRVLREEGLDPSAFLKMPRGLRVYGTYRRVRLEPAGFEYKIMGNDVFMQFTLPRGSYATVLLREVVKPAEPHKHGF
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: ANGL8_HUMAN
Sequence: MPVPALCLLWALAMVTRPASAAPMGGPELAQHEELTLLFHGTLQLGQALNGVYRTTEGRLTKARNSLGLYGRTIELLGQEVSRGRDAAQELRASLLETQMEEDILQLQAEATAEVLGEVAQAQKVLRDSVQRLEVQLRSAWLGPAYREFEVLKAHADKQSHILWALTGHVQRQRREMVAQQHRLRQIQERLHTAALPA
What is the function of this protein?
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577).  May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (By similarity).
What are the official names of this protein?
Angiopoietin-like protein 8, Betatrophin, Lipasin, Refeeding-induced fat and liver protein.
What is the protein family that this protein belongs to?
Belongs to the ANGPTL8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSE_HAEIN
Sequence: MTLDVWQHIRQEAKELAENEPMLASFFHSTILKHQNLGGALSYLLANKLANPIMPAISLREIIEEAYQSNPSIIDCAACDIQAVRHRDPAVELWSTPLLYLKGFHAIQSYRITHYLWNQNRKSLALYLQNQISVAFDVDIHPAAKIGHGIMFDHATGIVVGETSVIENDVSILQGVTLGGTGKESGDRHPKVREGVMIGAGAKILGNIEVGKYAKIGANSVVLNPVPEYATAAGVPARIVSQDKAAKPAFDMNQYFIGIDDGMNLNI
What are the official names of this protein?
Serine acetyltransferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAAB_PICTO
Sequence: MLDPEKFIKDSVSFIEKNVKRGILACSGGQDSTLLAVISSMAKTDILTVFIDTGLLRNNDIKRIKEIFSSYNVNGRILDRSSLFISRLRNVTDPEEKRKIIGRTFIEVFEEEAKNYGAESLLQGTIAPDWIESGGGSRDTIKSHHNVGGLPEKMNLRLVEPLRDLYKDEVREVSRYLGLPEVQPFPGPGLAIRIIGEVTEEKLNILRRATDIVEYESSKLNDKPWQYFPVLLPVRTTGIHGDQRTYGLTIAIRFIDTIDGMSGTFSRPDWSVLENISNRITDEIPEINRVVYDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.