PharMolix/UniProtQA huggingface dataset:
Protein: FENR_RHOPS
Sequence: MTEAIKTDVLIVGAGPCGLFAVFELGLLDIKVHLVDILDKVGGQCAELYPEKPIYDIPGIPMITGHGLTESLMEQIKPFNPTIHLNEMIESVEKIGDPEFRVITNAGTVFECKVLVVAAGGGSFQPKRPPVPGVEAYEGKSVHYAVRKMEEFRGKDIVIVGGGDSALDWTLNLNPICKSMTLVHRRDDFRGAPHSVEQMRQLVASGKLDLKIGQITELQGDNGQLSGATIKLNDNSVAQIKCDAMLPFFGLTMKLGPVANWGLQLENNLIPVDTGTFETNVPGIFAIGDINTYPGKLKLILSGFHEGALMAQKAVKYVYPDKRVVFQYTTSSTNLQKKLGVN
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: YIDD_CAMC1
Sequence: MKKFAIKFIAFYQKYISILLPKSCRYYPTCSQYAIWEFQTNSFFSAFFATFMRILRCNQLFKGGINYPIIRKKFNSCFIFQKSDTKNVNFWFIPCQNSKFYVVKVLDKLKEKN
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARNC_SERP5
Sequence: MSRVEPIKKVSVVIPVYNEQESLPALLERTTAACKQLTQPYEIILVDDGSSDNSADMLTAAAEQPGSCVIAVLLNRNYGQHSAIMAGFNQVSGDLVITLDADLQNPPEEIPRLVKVAEEGYDVVGTVRANRQDSWFRKSASRIINMMIQRATGKSMGDYGCMLRAYRRHIIEAMLNCHERSTFIPILANTFARRTTEIEVLHAEREFGDSKYSLMKLINLMYDLITCLTTTPLRLLSVVGSVVALSGFLLAVLLIALRLIMGPEWSGGGVFTLFAVLFTFIGAQFVGMGLLGEYIGRIYTDVRARPRYFVQKVVGEQPNHNTQEEE
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TDA7_YEAS8
Sequence: MNSNSTIGRTTLGESDTISLSFSEPSSSLNSRSTDVVFASTSTLVPQQGSLTSLPPVSSTATPTYYSTSLTYDETLHTSIDVSSTSTLVSSTDSSSSSEQDTYSSQYDPATSSYSIITPSMSIFSSTSPMSSSSSITSEWSSLTSTTPTLSSSATSLSSSWSSLSSPSSLLVSSSLSSSSYSDTKLFSFDSRSSIFSPSTPTVISPSYTYLSSISATSFQISTTSELSSSWFSTISPSTTSNKDTTFPSSSRNTSTSFYSSSLSSTNDFSTISKSSKLSPSASSSTVSISTISVPTSSSVSSSSSKVPSNRPSSSSSSDDTTSAYSSTYTFQSLQSTTSSSIPPTTQTPSTSTISTSPIPTSSQVFNTAAISSSEDSKTIYYFYTQTYDITDSSTTFVTGLPTTIAVAKSEVTSFSAPSSTITADMSFYQHWLDGSLDNNKNQGPSKTNTGTIVGSVVGSVGGILICVLVVWFMLVRKRKAKRHFKENDSFCHEIGRRTGFPTTAQAKEASLQAQDSGSQQRNTETASANNPFSNEFNFKARGNPPPVPPPRNVTATNGSFQNMRSNFMDQENRFSYGSSFTYSSLGSSTQGGFSTLSSNSIRLGRGLDNDISHDERNTVQNNSQGFLREII
What are the official names of this protein?
Topoisomerase I damage affected protein 7.
What is the protein family that this protein belongs to?
Belongs to the TDA7 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: RL16_XANCB
Sequence: MLQPKRTKYRKMHKGRNDGLAWSGNAVSFGEYGLKATAHGQLTARQIEAARRTISRHVKKGGKMWIRVFPDKPITKKPIEVRMGSGKGNVEYWVAQIQPGRMIYEIEGIPEDIAREAFRLAAAKLSVTTTFVTRTVR
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: AC4CH_HAEIN
Sequence: MQPNDITFYQRFEADILAGHKTISIRDDSESHFKAGDILRVGRFEDNQYFCNIEVLSVSPITLDELTQPHAKQENMGLDELKEVIRGIYPNEIIFWVIQFSLKEYFNEEKCVREIIITDRKFN
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: PCNA_THEON
Sequence: MPFEIVFDGAKDFADLIATASNLIDEAAFKITEEGISMRAMDPSRVVLIDLNLPESIFSKYEVEEEETVGINMDHFKKILKRGKNKDTLILRKGDENFLEITFEGTAKRTFRLPLIEVEELELDLPELPFTAKVVVLGEVLKEAVKDASLVSDALKFIARENEFIMKAEGETNEVEIKLTLEDEGLLDLEVEEETKSAYGISYLADMIKGIGKADEVIIRFGNEMPLQMEYPIRDEGKLIFLLAPRVED
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: ECSIT_XENTR
Sequence: MRTLRFLISARHLCARGRGIPAGQALGTGNNAQKQVTCCLHTSPPPGPPQATSSAGSVTPYEDVFQREQRNKASFVEVLDLYCNRDVRRRGHVEIIEAALRWMTEFGVEKDLEVYNKLLDVFPKEVFVPQNYIQRMFNHYPRQQECAIRVLEQMENYGITPNKQTCFLLLQIFGARSHPIRKYQRMMYWFPRFKHTNPFPVPAELPADPVELSRMCLHRIANDLDSRVAVYQMPYTEKCDDGKEREHLHVVGIQSPSQVSLLAAHNPSTPVYVEGPFPLWLRKTCVYYYILRADPDPMRKEEEIDNERSLYYPLSLDLELDRDLGDDDSFDVDDVEEGPVFAMCMAGSGDELLLGKWIRGLQETNPILGQTPVVFRLNSGPQELSVPQEKEAEPKGELEDDEGEREPERRRMEQ
What is the function of this protein?
Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
What are the official names of this protein?
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ECSIT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: RL34_BARQU
Sequence: MKRTYQPSKLVRKRRHGFRARMATAGGRKVIAARRARGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS17_STACT
Sequence: MSERNDRKVYVGRVVSDKMDKTITVLVETYKTHKLYGKRVKYSKKYKTHDENNSAKLGDIVKIQETRPLSATKRFRLVEIVEESVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: TM231_RAT
Sequence: MALYHLFSHPIERAYRAGLCSKAALFLLLATALTYIPPLLVAFRSHGFWLKRSNYEEQPNVRFQHQVLLVALLGPEPGAFLAWSTYPTFNRLQGVHLRVPLVSTREEDRNQDGKMDVLYFKLELPLQSTEQVLGVQLILTFSYQLHRMSTFEMQSMAFLQSSFAVPGSQLHVNGDLRLQQKQPLSYRGLDVRYNVSVINGTSPFAHDYDLTHIVAAYQERNVTTVLSDPNPIWLVGRAAEAPFVIDAVIRYPVEVISYQPGFWEMIKFAWIQYVSILLIFLWVFERIKIFVFQNQVVTSIPVAVPQGEIRKEHLS
What is the function of this protein?
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
What are the official names of this protein?
Transmembrane protein 231.
What is the protein family that this protein belongs to?
Belongs to the TMEM231 family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Note=Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone.
Protein: VM2JA_BOTJA
Sequence: RTDTVSTPVSGNELLEAGEECDCGTPGNPCCDAATCKLRPGAQCAEGLCCDQCRFMKEGTVCRRARGDDMDDYCNGISAGCPRNPFHA
What is the function of this protein?
Binds alpha-5/beta-1 (ITGAV/ITGB1), alpha-V/beta-3 (ITGAV/ITGB3) and alpha-M/beta-2 (ITGAM/ITGB2) integrins.  Is a potent inhibitor of platelet aggregation induced by ADP, collagen, and thrombin.  Induces neutrophil chemotaxis and inhibits the chemotaxis of human neutrophils toward fMLP, IL-8, and jarastatin itself.  Directly activates an integrin-coupled signaling and modulate the MAPK pathway in different ways, leading the neutrophils to express different functional response.  Jarastatin-treated neutrophils accumulates F-actin at the plasmalemma.  Induces PTK2/FAK1 and phosphoinositide 3-kinase (PI3K) activation.  Induces Erk-2 translocation to nucleus and a delay of the spontaneous apoptosis of neutrophils.  Increases the IL-8 mRNA levels in neutrophils.  When injected simultaneously with melanoma cells in mice, jarastatin, flavoridin (FL) and kistrin (KR), significantly reduce tumor lung colonization.  Jarastatin inhibits B16F10 cell growth in vitro.  When it interacts with melanoma cells, it induces actin cytoskeleton rearrangement, increasing actin polymerization and PTK2/FAK1 phosphorylation.  Interferes with NF-kappaB translocation in melanoma cells.
What are the official names of this protein?
Disintegrin jarastatin, JT, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MYO1_LODEL
Sequence: MAIVKRGGRTRAKQQQAPAKVNNGLGAGAGAGGGIQKAEFDITKKKEVGVSDLTLLSKITDEAINENLHKRFMNDTIYTYIGHVLISVNPFRDLGIYTLENLNKYKGRNRLEVPPHVFAIAESMYYHLKSYGENQCVIISGESGAGKTEAAKQIMQYIANVSVDSGNAEISKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFSEGSYQPIAAHITNYLLEKQRVVSQITNERNFHIFYQFTKHCPPQYQQQFGIQGPETYVYTSAAKCITVDGIDDGKDFKDTLNAMNIIGLSQAEQDNIFRILALILWTGNISFVEDESGNAAIRDDSVTNFVAYLLDVNAEILKKAITERTIETSHGMKRGSTYHVPLNIVQATAVRDALAKGLYNNLFDWIVERVNLSLQGNQGQSEKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQDEYVQEQIKWTPIDYFNNKVVCDLIEATRPQPGLFAALNDSIKTAHADSDAADQVFAQRLSMVGASNRHFEDRRGKFIIKHYAGDVTYDVAGMTDKNKDAMLRDLLELLGTSSNAFVTQTLFPPNLLSELVDSKKRPETASDKIKKSANILVDTLSQATPSYIRTIKPNQTKKPRDYDNQQVLHQIKYLGLKENVRIRRAGFAYRSTFQRFVQRFYLLSPATGYAGDYIWQGDDLTAVKEILRACHIPTSEYQLGTTKVFIKTPETLFALEDMRDKYWHNMAARIQRAWRRYIKRKEDAAKTIQRAWRMKNHGNQFEQFRDYGNSLLQGRKERRRFSMLGSRAYMGDYLACNDKTGFGRFVVNQVGIKEPVVFSAKGVILLSKFGRSSKRFPRIFVLTKSNLYIIAEVLVEKRLQLQREFALPVHLIKSVGLSQLQDNWVAVCLLSPTTTTPDVFINLDFKTELVAQLKKLNSGLSILIGPTVQYQKKPGKYQTVKFAIGSGPHIPPLIDSYKSGTVTVNQGLPPTSKNPKRPRAKLGKVDYSKYYNRGVRSLAQPAFQSQPTASYRSEPAYPQPTTQLYATQHQPQQPQVPTRTASRKAPPPAPSTQTAAQVSTLPQAARKPAAPARPAKKIAPQPPVKKAVSPQPPAKKTVAAPPPPPPPPALSKPKHPTYRAMYDYDGSVAGSVPLVKDTIYYVLQINGKWGLVKTMDETQEGWSPIDYLQEESSPSASAATQSYAPTTASSNPVSTASSNTYTNTTQATTMLNGSLGNGLADALKAKKSEETTLAGSLADALKKRQGVTRDDSDAEDDDDDDDW
What is the function of this protein?
Type-I myosin implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
What are the official names of this protein?
Myosin-1, Class I unconventional myosin, Type I myosin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: MUTH_SALA4
Sequence: MSALCPLLTPPASEALLLAQARQLSGYTLGELAAMAGITTPKDLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWVPVEGDRSIPLAERRVGSPLLWSPSEEEDRQLRLDWEELMDMIVLGQVERITARHGEVLQLRPKAANARALTEAIGARGEPILTLPRGFYLKKNFTQALLARHFLLQNP
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDB1B_ARATH
Sequence: MSVWNYAVTAQKPTCVTHSCVGNFTSPQELNLIVAKSTRIEIHLLSPQGLQTILDVPLYGRIATMELFRPHGEAQDFLFVATERYKFCVLQWDYESSELITRAMGDVSDRIGRPTDNGQIGIIDPDCRVIGLHLYDGLFKVIPFDNKGQLKEAFNIRLEELQVLDIKFLYGCTKPTIAVLYQDNKDARHVKTYEVSLKDKNFVEGPWSQNNLDNGADLLIPVPSPLCGVLIIGEETIVYCSANAFKAIPIRPSITKAYGRVDLDGSRYLLGDHAGLIHLLVITHEKEKVTGLKIELLGETSIASSISYLDNAVVFVGSSYGDSQLIKLNLQPDAKGSYVEILEKYVNLGPIVDFCVVDLERQGQGQVVTCSGAYKDGSLRIVRNGIGINEQASVELQGIKGMWSLKSSIDEAFDTFLVVSFISETRILAMNIEDELEETEIEGFLSEVQTLFCHDAVYNQLVQVTSNSVRLVSSTTRELRNKWDAPAGFSVNVATANASQVLLATGGGHLVYLEIGDGTLTEVKHVLLEYEVSCLDINPIGDNPNYSQLAAVGMWTDISVRIFVLPDLTLITKEELGGEIIPRSVLLCAFEGISYLLCALGDGHLLNFQLDTSCGKLRDRKKVSLGTRPITLRTFSSKSATHVFAASDRPAVIYSNNKKLLYSNVNLKEVSHMCPFNSAAFPDSLAIAREGELTIGTIDDIQKLHIRTIPIGEHARRICHQEQTRTFAISCLRNEPSAEESESHFVRLLDAQSFEFLSSYPLDAFECGCSILSCSFTDDKNVYYCVGTAYVLPEENEPTKGRILVFIVEEGRLQLITEKETKGAVYSLNAFNGKLLASINQKIQLYKWMLRDDGTRELQSECGHHGHILALYVQTRGDFIAVGDLMKSISLLIYKHEEGAIEERARDYNANWMTAVEILNDDIYLGTDNCFNIFTVKKNNEGATDEERARMEVVGEYHIGEFVNRFRHGSLVMKLPDSDIGQIPTVIFGTVSGMIGVIASLPQEQYAFLEKLQTSLRKVIKGVGGLSHEQWRSFNNEKRTAEAKGYLDGDLIESFLDLSRGKMEEISKGMDVQVEELCKRVEELTRLH
What is the function of this protein?
Component of light signal transduction machinery.  Involved in repression of photomorphogenesis in darkness (By similarity).  Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB) (By similarity).
What are the official names of this protein?
DNA damage-binding protein 1b, UV-damaged DNA-binding protein 1b, DDB1b.
What is the protein family that this protein belongs to?
Belongs to the DDB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPF_METM6
Sequence: MFIKICGIKTPEELEIVENYGNATGVILECSSKRRIGFETAKNLVNLSNIPVFAVSTTSKVSVWENIIELTGTNYLQMHSDIDQKAIDFIKNEYGCFIMKSFKIPEKSESPENDAEKIISDIESYEVDRILLDTGKGCGQTHDHRISQIIAKKFEIVLAGGLDPDNVFEIVKVVNPFGVDVSSGVENNNSKDEELIKRFCENVKLGENYEM
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: TM209_HUMAN
Sequence: MMQGEAHPSASLIDRTIKMRKETEARKVVLAWGLLNVSMAGMIYTEMTGKLISSYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQTLLGLKTAVVQTTPPHDLAATQIPPAPPSPSIQGQSVLSYSPSRSPSTSPKFTTSCMTGYSPQLQGLSSGGSGSYSPGVTYSPVSGYNKLASFSPSPPSPYPTTVGPVESSGLRSRYRSSPTVYNSPTDKEDYMTDLRTLDTFLRSEEEKQHRVKLGSPDSTSPSSSPTFWNYSRSMGDYAQTLKKFQYQLACRSQAPCANKDEADLSSKQAAEEVWARVAMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQMRRMGCPELQIGEASITSLKQAALVKAPLIPTLNTIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAINPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE
What are the official names of this protein?
Transmembrane protein 209.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BPT_CUPPJ
Sequence: MSKLKELPLSALQFYATAPYACSYLDGRMARSQVATPAHLINADVYSRLVRAGFRRSGIFTYRPYCDECHACTPCRVLVEQFEPDRSQRRAWRRHGHLQALVAPLTYVEEHYSLYLLYQSMRHAGGGMDQDSRDQYEQFLLQSRVNSRLVEFREPPGSPEAGKLRMVSMIDVLDDGLSSVYTFYDPLERNASYGTYNILWQIRQTRELGLPHLYLGYWIAESRKMAYKARFRPLQVLTGNQWQAFEDDGVSAATAAPPDEPGPVQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPS_STAAC
Sequence: MELQLAIDLLNKEDAAELANKVKDYVDIVEIGTPIIYNEGLPAVKHMADNISNVKVLADMKIMDAADYEVSQAIKFGADVITILGVAEDASIKAAIEEAHKNNKQLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKNSKVAVAGGIKPDTIKDIVAESPDLVIVGGGIANADDPVEAAKQCRAAIEGK
What is the function of this protein?
Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
What are the official names of this protein?
3-hexulose-6-phosphate synthase, HPS, D-arabino-3-hexulose-6-phosphate formaldehyde lyase.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. HPS subfamily.
Protein: XTH_WHEAT
Sequence: MKATAGALLAVVAAVLLRGVAAAPRKPVDVPFDKNYVPTWAQDHIHYVNGGREVQLSLDKTTGTGFQTRGSYLFGHFSMHIKLVGGDSAGTVTAFYLSSQNSEHDEIDFEFLGNRTGQPYILQTNVFSGGKGDREQRIYLWFDPTKDYHSYSVLWNLYMIAFFVDDTPIRVFKNSKDLGVRYPFDQPMKLYSSLWNADDWATRGGREKTDWSKAPFVASYRGFHVDGCEASAEAKFCATQGARWWDQPEFQDLDAAQYRRLAWVRKEHTIYNYCTDHDRYAAMAPECKRDRDV
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
What are the official names of this protein?
Probable xyloglucan endotransglucosylase/hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: MPI7_LYMST
Sequence: MNASVESCLTFTFVLVALCVGLTIGQQVNTCTMFSRQHPRGLCGNRLARAHANLCFLLRNTYPDIFPRKRSVDNTFEKVYSIPLSVLAELDLSDDDWGAYVSKKDIPYRSETNGLSGANFESSAFDKQLELPAMKSTTSQLFRILKLRGSRLKREVMAEPSLVCDCCYNECSVRKLATYC
What are the official names of this protein?
Molluscan insulin-related peptide 7, MIP VII.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Protein: ZUPT_XANCP
Sequence: MLEVSSHNVWTALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVFVSLSEILNKSIASFSNAYNDKLGFTYGTLTFLGGMLLIMVIDRLVPNPHQSLSTDDPQFRDDNRAYIRRVGLLTAVAITAHNFPEGLATFFATLESPAVGMPLAFAIAIHNIPEGIAIAVPVYFATRNKFYAFGASLLSGLAEPIGAGIGYLLLSSVLSEAVFGAVFGVIAGVMVFLALDELLPAAKRYAQGHETVYGLVSGMGTLAISLVLFRYAAP
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXD1_LEGPH
Sequence: MNSSLRDIANLVQGMVIGNDAITVSTLSPIDNILPGSLVFAEGEDNIKLAENSEAAAILIGQGTIDSPKPLIQVKNPFKAFIALLNHFYPPRRISPGVHPTAVIGAEVQLGDEVYVGPFVVIESGSIIGNHSVLKSHIHIGHNVVIGDHTTIHPQVTIYDNCRIGSNVTIHASTVIGSDGFGYTFVDGQHLKVPHSGYVVIENNVEIGANTAIDKATLGATVIGEGTKIDNLVQIAHSVKLGKHNIICAFTGIAGSTTTGNNVIFAANVGVSDHVHIEDEVILGARTGVPPHKHLKKGTVYLGNPAKPKDVAIKHELSVNRIPLIRKNIKSLTEQVAVINKKLDIKAKEVE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: PNP_RUBXD
Sequence: MRLEIPVGERAIVLETGKLARQAGGAVTARFGDTTVLSTATRSEEPRPGATFLPLSVDIEERMSSAGKIPGGFLKREGKPSEKAILTARLTDRPIRPLFPKDYYYEVQVIGTVLVADQENPYDVVSMVGASAALALSDIPFGGPIGAVRVGRHPDGGFILNPTYQQLEESDLDIVVAGTKEAITMVEAGAREVTEDVVVEALEVAQGVIREQAEAIERWAAEHGEEKQPFEEPGENPFVEELRGAYLERIKEGLISTDRRARHEAIDLLKEELVEGRSEEEVPLVLDALAQLQKEAFRKLYLEDRKRTDLRAFDEIRPTTAEAHVLPRVHGTGLFTRGETQVLSSLALADLGLVQRLDTLEPQTTKRYMHHYYFPPYSTGETGRLGPPRRREIGHGALAERALLPVIPSEEEFPYAIRIISEVLESNGSSSMASVCGSTLALMDGGVPIKAPVAGVAMGLVKEGDDYVILTDIQGLEDHMGDMDFKVAGTRDGITALQMDMKITGVSAELLKEALEQARRGRLQILDIMREEIAEPRPEISDHAPRVEVIQIPTDKIGLLIGPGGKTINALQDEYGVNISVENDGTVYVAGVEGMSVKAAVSAIKGMTKEVEAGDIYVGKVVKTTNFGAFVELTPGRDGLLHISRLAPGKQRVRRVEDVLNEGDVVKVRVLEIDKQNRISLEMVED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_PARUW
Sequence: MRLSIIEIINSMFSIRLFSPAKINLFLKVIGKRADGYHELSSLFQTISAGDILTFQRQTIDTLTCSDPYLPTDDSNLVLKAMRLFRSKTGLDLHLRIHLDKRLPSQAGLGGGSSNAATTLWACNQLAGEIVTTEELMQWGSEIGADIPFFFSKGTAHCTGRGECVNSLEPLAHCKIWIVKPPFGLSTPEVYKHLNFSQPNENNNDYASFKEKPYFNDLEASAFEIKPELKILKNTLLSSGFDTVLMSGSGSSFFCIGQGQIPASFKAFSAYFINRSSNRWYSTLPKLT
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MYSC_CHICK
Sequence: KIKPLLKSAETEKEMANMKEEFLKLKEALEKSEARRKELEEKQVSLVQEKNDLLLQLQAEQDTLADAEERCDLLIKSKIQLEAKVKELTERVEDEEEMNSELTSKKRKLEDECSELKKDIDDLEITLAKVEKEKHATENKVKNLTEEMATLDENISKLTKEKKSLQEAHQQVLDDLQAEEDKVNTLSKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESVMDLENDKLQMEEKLKKKEFEMSQLNSKIEDEQAIVMQLQKKIKELQARIEELEEELEAERAARAKVEKQRSDLARELEELSERLEGAGGATAAQLEMNKKREAEFLKLARDLEEATLHYEATAAALRKKHADRRGEMGEQLDNLQRVKQKLEKEKSELKMEVDDLTANMEQTVKGKANAEKLWGTYEDHLNETKTKLDEMTRLMNDLTTQKTKLQSENGEFVRQLEEKESLISQLSRGKTSFTQQIEELRRQLEEETKSKNALAHALQAARHDCDLLREQYEEEQEAKAELQRALSKGNAEVAQWRTKYETDAIQRTEELEDAKKKLLARLQEAEEAIEAANAKCSSLEKAKHRLQNEQEDMMIDLEKANSAAASLDKKQRGFDKIINDWKQKYEESQAELEASQKEARSLSTELFKLKNAYEETLDHLETLKRENKNLQEEISDLTNQISEGNKNLHEIEKVKKQVEQEKSEVQLALEEAEGALEHEESKTLRFQLELSQLKADFERKLAEKDEEMQNIRRNQQRTIDSLQSTLDSEARSRNEAIRLKKKMEGDLNEMEIQLSHANRHAAEATKSARGLQTQIKELQVQLDDLGHLNEDLKEQLAVSDRRNNLLQSELDELRALLDQTERARKLAEHELLEATERVNLLHTQNTSLINQKKKLEGDISQMQNEVEESIQECRNAEQKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQKRLDEAEQIALKGGKKQIQKLESRVRELENELENELRRNSDAQKGARKFERRIKELTYQSEEDKKNLARMQDLIDKLQLKVKSYKHQAEEAEAQANLYLSKYRKQQHDLDDAEERAEIAESQVDKLRSKSRDIGMKKVDAEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin heavy chain, cardiac muscle isoform.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: ASC3_DIDFA
Sequence: MPAATTSIFYLPDINIAPWLESPTSPSGQQVVDQVRKACTSTGFFQLTGHGLSQDVVEDIFAASAKFFALPKDVKQGLNFTKNLGFRGYELIGAQVYESDVLPDLKEGFLAGIDLPFEDMRVQNKRFFAGQNVWPPPDVLPYAEFREPVEKYYKSIMQLCFTVMDLVAATLPYGPDVFDEWKSHEPACPLRLLHYPPTPAHVAGKTRQLGSSAHTDFGALTLLLQDSHEGLEVLNHDTGDWVLVPPKPGAFVVNIADMMTMVTVGEYKSSKHRVINRNETEDRYSVVFFMDGNVDYKLRRLDKIGQPIGDDEDLLTVEDYMLGKRNSTYVK
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of the selective antifungal agent ascochitine, an o-quinone methide that plays a possible protective role against other microbial competitors in nature and is considered to be important for pathogenicity of legume-associated Didymella species (PubMed:31554725).  The pathway probably begins with the synthesis of a keto-aldehyde intermediate by the ascochitine non-reducing polyketide synthase pksAC from successive condensations of 4 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit (Probable).  Release of the keto-aldehyde intermediate is consistent with the presence of the C-terminal reductive release domain (Probable).  The HR-PKS (orf7) probably makes a diketide starter unit which is passed to the non-reducing polyketide synthase pksAC for further extension, producing ascochital and ascochitine (Probable).  The aldehyde dehydrogenase (orf1), the 2-oxoglutarate-dependent dioxygenase (orf3) and the dehydrogenase (orf9) are probably involved in subsequent oxidations of methyl groups to the carboxylic acid of the heterocyclic ring (Probable).  The ascochitine gene cluster also includes a gene encoding a short peptide with a cupin domain (orf2) that is often found in secondary metabolite gene clusters and which function has still to be determined (Probable).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase, Ascochitine biosynthesis cluster protein 3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.