PharMolix/UniProtQA huggingface dataset:
Protein: SYCC_XENLA
Sequence: MTESWEQGKGRRTQPPWSAPNTNEQPGLRLYNSLTRSKELFFPQVGRKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFKYDVFYCMNITDIDDKIIKRARQRHLFQQYRESNPPHSDLLQDVNTALIPFLQRISETNDPDKKQMLERIQTAVSAALLPLQDALNKNTGAEELQKHSQVLMEAAVDLLSDWLDEKHGAQIADNSIFSQLPKYWEGEYHKDMEALNVLTPDVLTRVSEYVPEIVAFVQKIVDNGYGYVSNGSVYFSTAKFHDSENHFYAKLVPEAVGDQKALQEGEGDLSISADRLSEKQSPNDFALWKASKPGEPSWESPWGKGRPGWHIECSAMAGSILGESMDIHGGGFDLRFPHHDNELAQSEAYFDNDHWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALQKNTARQLRLAFLMHSWKDTLDYSNNTMESAVQYEKFMNEFFLNVKDLLRAPTDITGQFVKWEVLEIELNNCFYSKKAAIHEALCDNIDTRTVMEEMRSLVSQCNSYIASKKVAKQFPNRMLLRSISSYLTSMLKVFGAIEGEEVIGFPIGGSENSMNLESTVMPYLQVLSQFREGVRQIARQHKVTEVLQLSDLLRDDILPELGVRLEDHEGLPTVVKLVDRETLLKEKEEKRKAEEEKQRKKEEAARKKQQQEAAKLEKMKISPSQMFTLETDKYSQFDESGFPTHDTEGKELSKGQTKKLRKLFEVQEKLHKEYLQMVQNGTTA
What is the function of this protein?
Catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).
What are the official names of this protein?
Cysteine--tRNA ligase, cytoplasmic, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECOT_SHIB3
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAEVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1851_SYNY3
Sequence: MKTMDAQEILRCYAQGQRDFSHINLVRVCLSNASLIGAQLIFVDLGGANLTRAQLDSATLKNANLALANMTEVCLIYADLSNADLSGANLVGADLTNADLSGAKLGGADLRKANLSEASLRGADLRGVNLIEANLTNTDFSEADLTGAYISDGAVINVVNLS
What are the official names of this protein?
Uncharacterized protein slr1851.
Protein: PSAJ_SYNR3
Sequence: MKKFLTTAPVFAAIWFTVTAGIMIEFNRFFPDLLFHPL
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RL14_HAEDU
Sequence: MIQEQTMLDVADNSGARSVMCIKVLGGSHRRYAAIGDIIKVTVKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNTEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RLMD_VIBC1
Sequence: MARIFQPKKKTQLNTRHQAVQVERLDHHGAGIAYLKKKPLFIDGALPGEEVVTQLVEEKSKFARGKLIKILKPSEARVEPFCSHYHECGGCDLQHLNYDQQLTHKQQTLRQLMRKFAGSDIELGAPVLGESLGYRRRARVSLFVDKKTRQLHFGFRKKQSKQIAQVTDCPVLAPELNVLLPEIYSTLKAFKKPEQLGHVELVLGDNAPCITLRHLNKLTEKETNTLVELAKRHQASLYLMPETDQLDLVEGEVPFYQEAGVTVPFTPNNFIQVNQAVNQKMVAQAVDWLDPKSDERVLDLFCGLGNFSLPIAKRAKHVVGVEGVAEMVEKAVNNASLNQINNARFYHANLEQDFEGQVWAAEQFDKVLLDPARAGASGIIDQVSVLGARRIVYVSCNPATLARDSQSLLEQGYQLTKLGMLDMFPHTSHLESMALFEKS
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: YPQE_BACSU
Sequence: MLKKLFGMGKIQEKVTEEVIYSPADGTVMDLSDVPDPVFSQKMMGEGIAVEPSSGEIVSPAEGEVIQIFHTKHAVGIRTRSGIELLIHVGLETVNMNGEGFTAHIKEGDKVKVGDPLITCDLELIKEKASSTVIPIVIMNGEAVGSMVSAGEKAARKGESKLFTIKAK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.
What are the official names of this protein?
Putative phosphotransferase enzyme IIA component YpqE, Putative PTS system EIIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_MYCLE
Sequence: MTPADLAELLKTTAIVVLAERGLDAAALPQTVTVERPRNPEHGDYSSNLAMQLGKKVGANPLELAGWLAEVLAQAGGIADVEVAGPGFINMRLDASAQAMIVNTVINADKNFGHSDDLAGYQINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAAVVREYYFNDHGAQIDRFTNSLIAAAKGELTPADGYAGTYVTDIAAQVMQQAPYALSLPESEMHETVREIGVDLMFTHIKKSLHEFGTDFDVYTHEDSMHASGRVDEAIARLRDTGNVYEKDGALWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPAIVEVLIGQMVNLVCDGQLVRMSKRSGNVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSSSNENPVYYVQYAHARLSALARNAAEFGLIPDTGHLELLSHDKEGALLRTVGEFPQVLKTAAALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEKPTDLHTARLALCQANRQVIANGLAILGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_RUEPO
Sequence: MICETVEEFAAALPPFSALAGLDLGDKTIGVAVSDRMRGVATPLETIRRKKFGLDASALLAIVEQREIAGIVLGLPRNMDGSEGPRCQSTRAFARNLSRLTEVAITFWDERLSTVAAEKALLEADTTRKRRSEVIDHVAAAYILQGALDRLRNL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLR24_PLAVT
Sequence: MRGAFYVAIALLGSHTAAECNQDEPQGAPNNDFLTFGGTIEKMLPRRVLRERRDSKDKLTVHAGAEERVMDPPPEAVEQAIMKTAGVMRTDSDDVIARAAGAIRAHEEIEALFRRIDPTLYNVNGQALHALPKPTNYMVSVASDIPTVPAKRAKVKASADVINNAAWRVSKHDLRLAPPEPSPSSIASSGIRFDNQPIAEKAFKLDLNKHSDEVEIINSNSKRKRIDLTPSHVGEQAPHPLPELQKYKVSVAVSIPMVLATKLEGDGPTLIMRNAANIITTHDFRPAPFGSSTRTVASSNSQIHSQPIAQEASKFALNVDPNEVKSLFHENLPLVGHALHTRVGNDELVPLATVNSIKAGNTQGPYVHKPRMATDEEIHAAFLEAFNLPFHQYLYETSIMIKIVKRQYKTSPGNHRIVESFSSLVNNQELSKLKESLGPDLQNLLAGMLELQDDLKSLREAYYVKLLIMYELFYDFCYVRLDLFDALVPKVDRTVWILKLKNYETLPSHD
What is the function of this protein?
Secreted effector that acts as an elicitor that induces cell death in host plant cells.
What are the official names of this protein?
Secreted RxLR effector protein 24.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Localizes to speckle-like structures within the nucleus.
Protein: ATG7_BOTF1
Sequence: MNLPEYHRLAAYITSDHSQDYTQDTNVAFIEEGPWDGEEEELITSFSTVEDLYTAICVREDNNQLDMALKFAPFASEIELPFYTALSQLKIDHDKLDDSARPVLGLYEPRATQSPDQSSRMRVLGNALSSNEVPSGHIRAEGKIKNVNTIEDFKNMDKQAMLQTSAKQIWDAINDGTIYSIPSLLSSFTILSFANLKKYTFTYWFAFPALHSEPAWRKVEQPPKFSAEETTALTEELGTWRYSHDNREHGFFLAKRVYPSSEHPQDPESESTSDLPFKWVIGSLREFESGFFNGVDAKNQYVSFVDPSTYHENPGWMLRNLLVLVRRRYKLDKVQILCYRDNHAKRHVPQSLILILESIYDPEYQSTAPDQIPKVTGWERNSLGKLTAKVTNLAQYMDPAQLADQAVDLNLKLMKWRIAPELNLDAIKNTKCLLLGAGTLGTYVSRLLMGWGVRKITFVDNASVSFSNPVRQPLFDFKDCIDGGAKKAYRASEALQEIYPGVDSTGHVMAVPMLGHPITDEAATKMNFELLQKLIEDHDAIFLLMDTRESRWLPTVMGKAAGKIVMNAALGFDTYVVMRHGVTPEDGGPAALGCYFCNDVVAPSDSVKDQTLDQQCTVTRPGVAPEASSKLVELLASVLQHPLKGAAPAPKLSSNHQSGQLEFDRDPPNHPLGLVPHQIRGFLAAYKTMLISGPSYDCCSACSPKIVNAYKEDGWEFIKRALTEKDYITELSGLAEVQRKAEAAANDVEWDSDEEGMEDEEPELL
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy (PubMed:29417220).  Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity).  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity).  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Required for normal mycelial growth and conidiogenesis, and regulates sclerotial formation (PubMed:29417220).  Plays an essential role in pathogenesis (PubMed:29417220).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme atg7, ATG12-activating enzyme E1 atg7, Autophagy-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: NUDC_EMENI
Sequence: MSEQEPSSADLAAREAEEKQRKAAEEAEQATLPYKWTQTIRDVDVTIPVSANLKGRDLDVVLKKDSIKVKVKGENGEVFIDGQFPHPIKPSESSWTLETTSKPPGKEVSIHLDKVNQMEWWAHVVTTAPKIDVSKITPENSSLSDLDGETRAMVEKMMYDQRQKEMGAPTSDEQRKMDILKKFQKEHPEMDFSNAKIG
What is the function of this protein?
Required for nuclear movement.  May interact between microtubules and nuclei and/or may be involved in the generation of force used to move nuclei during interphase.
What are the official names of this protein?
Nuclear movement protein nudC, Nuclear distribution protein C.
What is the protein family that this protein belongs to?
Belongs to the nudC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RNPH_OCEIH
Sequence: MRNDQREVNQLRNINITTNYISHPEGSVLIEMGNTKVICNASIEDRVPPFMRGQGKGWITAEYAMLPRATAQRNIRESSKGKVSGRTMEIQRLIGRALRSVVDLDQIGERTVWIDCDVIQADGGTRTASITGAFVAMSLAFAKLVEAKTLKKTPIQDYLAAISVGVLTNGTEILDLNYEEDSEAAVDMNIVMTGEGEFVEIQGTGEEATFTPNQLQNMLKLGEEGIQQLVKIQKELLADKLLID
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: GPMB_ECO45
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLETRNIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: XTH21_ARATH
Sequence: MVSSTLLVMSISLFLGLSILLVVHGKDFNQDIDITWGDGRGNILNNGTLLNLGLDQSSGSGFQSKAEYLYGKVDMQIKLVPGNSAGTVTTFYLKSQGLTWDEIDFEFLGNVSGDPYIVHTNVYTQGKGDREQQFYLWFDPTAAFHNYSILWNPSHIVFYIDGKPIREFKNLEVLGVAYPKNQPMRMYGSLWNADDWATRGGLVKTNWSQGPFVASFMNYNSENACVWSIVNGTTTTSPCSPGDSTSSSSSSTSEWFSQRGMDSSSKKVLRWVQRKFMVYNYCKDKKRFSNGLPVECTAKNKNTKS
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
What are the official names of this protein?
Probable xyloglucan endotransglucosylase/hydrolase protein 21, At-XTH21, XTH-21.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 2 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: PYRB_DESVH
Sequence: MQNETRSLWPHKDLLDVDQLSKDELLHLLDTAAQFHEINRRPVKKVPTLKGKSVILFFAEPSTRTKTSFDVAGKRLSADTFSLAKSGSSLQKGESLKDTALTLEAMNPDVLVIRHSSSGAARFLAERLACGVVNAGDGWHAHPTQALLDCYSLRQVWGDTFEGRTLCILGDIAHSRVARSNVKLLTSLGVRVRLCAPRTLLPAGVGNWPVEVFTDLDAAVRDADAVMCLRLQLERQQAGLLPDLREYSNRYCLTPRRLELAKPEAKVLHPGPMNRGLEIASSIADAPASLVLDQVAAGVATRMAILFLLATRTDGGR
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: KDSB_OLEA2
Sequence: MTATACYGIIPARYDSSRFPGKPLADIQGRPMFWHVWHRASLCPQLQQVVLATDDGRIAEAAHALDVPYVMTRSDHPSGTDRVFEAATLLQLDEDAVVVNIQGDEPALEPRMLSELVRPFAEDAAVQVTTLARAISPQQAACPDVVKVVCTAGGDALYFSRAAIPYCRDGQSGAPCMGHVGLYAFRYQALRRFTQLEQSVLERTEKLEQLRLLENNIPIRVVETAYRTHGVDRPGDIDVIINMIRENEG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPT_LEPIN
Sequence: MIQNKLQNFVDTLPISPEKSCSYYPERLSQIQYFPFPEEISKEVLQFFFDSGFRRNGNILYRTSCCGCKDCLSYRIPLDQFVPSRNRKKLLKKNSDLKICFESPNLTLEKEILYLRYQRSRYQNFVIEESDQELLEGMRWNLFEYKENSLEMTLSLDGKILCFMILDFASDSLSAVYSVYDPDYPDRSLGSFAILSSILYAKELGMKYFHLGYFLPGHPNMDYKKYWTPAQIREPVSNENRWIETDDFQKRYSDFSW
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_COXBU
Sequence: MSSDEKLQILYCSFCGKSQHQVRKLIAGPAVFVCNECVDLCNDIIREEEIAQAGGAQKKLPTPPEIHRMLDEYVIGQEFAKKVLSVAVYNHYKRLGNQTKKDSVEISKSNILLIGPTGSGKTLLAQTLAKILDVPFAIADATTLTEAGYVGEDVENIIQKLLQKCNYDVEKAKTGIIYIDEIDKIARKTDSPSLTRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPQQEYLQVDTSNILFICGGAFADLHKIIQRRTDKSGIGFAAEVRPKEDFSREASKLIKQTEPGDLIKYGLIPEFVGRLPIITTLEELDEDALMRILTEPKNALVKQYRKLFEFEGVEIDFREDALKAIAKRAIQQKTGARGLRSIVEHTLLDLMYDLPGVAAGLRKVVIDSGVIDQASPPIFIYHHEKASRKVAQE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MURI_STRPD
Sequence: MDTRAIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVILPGASAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPIVESNEMCSSIAKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTANPEIFQEIASIWLKQKINVEHVTL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: FOLD_TREPS
Sequence: MDARLIDGKQAAHECTARLATRVQALRAAVGTAPFLAAVLVGDDPASCTYVAAKQRALARAHLRGETHRLPAHASHAQVLELIARLNEDARVHGILIQLPLPAHLDAARVCRAVAPEKDVDGFHPLNCGALFLAQPGFVPCTPAGIVHLLRRAQVPLAGARVVIVGRSAIVGRPLAVLLASPGCDATVTLCHSHTRGLADICVQADILVAALGKARFIGAPFVRTGAVVIDVGIHHVPDATAPRGRRLCGDVDFDAVAHKVQAITPVPGGVGPMTIAMLLHNTLCAAEYAAGMIPPFRAALYADLDGRAAGDVPH
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MGAT1_CAEEL
Sequence: MHAVTKIFIIFIFVFILWTLYVENDITNRTRNTDNIDDLLESANRLERLLKFEAKKIAALAEDVHKIRANRKGKHVIMEEMVSQDLKQWKDPIPVLVFSCNRAMAVRDHVEKLIRYRPSQEKFPIIVTQDCDNENVKNEVKKFGDKVEYIKHLAGDKANITIPPSHRQYTAYYRIARHYKLALNHVFVDKGYSSVIITEDDLDISPDFFSYFSSTRYLLENDEKLWCVTAWNDNGKQENIDMTAASTLYRSDFFAGLGWMMSSKTWHELEPIWPVGFWDDWMRDPARRKDRQCIRPEISRTGMMSYGKEGASKGQFFSKHLAKIKVNDKYINFGKIDLDYLLPANFAKKTNLEVMKEAVELSIDNVASFVLSSENKGKSVRVMYDGNIDYIRKADKLHIMHDFKAGVPRTAYDGIVTCFINGIRIYLVPDRTKVSAYNPDWSVPPSFGE
What is the function of this protein?
Initiates complex N-linked carbohydrate formation.  Essential for the conversion of high-mannose to hybrid and complex N-glycans (By similarity).
What are the official names of this protein?
Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, GNT-I, GlcNAc-T I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 13 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasm, perinuclear region.
Protein: HIS2_BIFAA
Sequence: MKTFESLFAELSEKAATKQAGSLTVDELAKGTHFIGKKIVEEAGETWIAAEYEGADRTAEEMSQLIYHLQVMMIDRGITLEDIYKNL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL332_STRPN
Sequence: MALKKASLACAVCGSRNYSIKISGNLKPTRLEVNKFCKHCGKYTTHRETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PCP_VIBVU
Sequence: MRKVLLTGFEPFGGESINPSLELVKQMASRALPQVEIIGCEVPVVRYQAIETVLQAVETHQPDLVLMIGQASGRCAITPERVAINLDDYRIEDNAGHQPVDEPIIATGPAAYFSTLPVKAITHALQQAGIPCQLSHSAGTFVCNHLFYGVQHHLHTRAIRSGFIHIPLLPEQASASNQPSMSLETLVHGLEMMMMTCLETEQDTKHTGGTIC
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_LACGA
Sequence: MNKLLIGLVNVYKKFISPVLPPTCRYYPTCSTYMIDALKKHGAILGLIMGISRIIRCNPFIKGGVDPVPDYFTLRRNPHPERYEDEIIAQAFHSNKK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: C_SENDN
Sequence: MASATLTAWIKMPSFLKKILKLRGRRQEDESRSRMLSDSSMLSCRVNQLTSEGTEAGSTTPSTLPKDQALLIEPKVRAKEKSQHRRPKIIDQVRRVESLGEQASQRQKHMLETLINKIYTGPLGEELVQTLYLRIWTMEETPESLKILQMREDIRDQVLKMKTERWLRTLIRGEKTKLKDFQKRYEEVHPYLMKEKVEQVIMEEAWSLAAHIVQE
What is the function of this protein?
The different products prevent the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways.  They inhibit IFN-alpha/beta induced tyrosine phosphorylation of STAT1 and STAT2.  Blocking the IFN-alpha/beta pathway requires binding to STAT1 in the cytoplasm.  They inhibit IFN-gamma induced serine phosphorylation of STAT1.  Block the IFN-gamma pathway by binding to and stabilizing the parallel form of the STAT1 dimer, further inducing high-molecular-weight complex formation and inhibition of transcription by IFN-gamma (By similarity).  May also have a role in preventing the cell to enter apoptosis.  Modulate regulation of viral transcription and replication.  Overexpression inhibits the viral RNA polymerase.  The absence of all C', C, Y1 and Y2 proteins leads to viral delayed growth.  Plays an important role in virion particles release.  Modulates virion shape.
What are the official names of this protein?
Protein C'.
What is the protein family that this protein belongs to?
Belongs to the respirovirus protein C family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Protein C' seems to localize around the Golgi.
Protein: 3MGH_MYCPA
Sequence: MRDAAEQLLVDPVEAARRLLGATLTGRGVSGVIVEVEAYGGVPDGPWPDAAAHSYKGLRARNFVMFGPPGRLYTYRSHGIHVCANVSCGPDGTAAAVLLRAAALEDGTDVARGRRGELVHTAALARGPGNLCAAMGITMADNGIDLFDPDSPVTLRLHEPLTAVCGPRVGVSQAADRPWRLWLPGRPEVSAYRRSPRAPAPGTSD
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: PURR_SALHS
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVIDNAFAGGYMAGRYLVERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALINVPDNWIVQGDFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: DPCKG_PICTO
Sequence: MQLKFDHDLVLNQESINRIKEFSHSICSIDDIKKHGGRIITVGDVTTENLERAGLDIFIEVVDLKTKRGEKTYNHRENSISIENRPGTISLSLIRAIESSIKSNKKTRIEINGEEDLAVIPIIFYGDINTLVVYGVPDTGMACIFINTEIKSMVTDILRDLNGKT
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: HIS1_BURP1
Sequence: MSAPLTLALSKGRIFEETVPLLAAAGVTVAEDPETSRKLILPTTDPNLRVIVVRATDVPTYVEYGAADFGVAGKDVLLEHGGGGLYQPIDLNIARCRMSVAVPAGFDYANAVRQGARLRVATKYVETAREHFAAKGVHVDLIKLYGSMELAPLVGLADAIVDLVSSGGTLKANNLVEVEEIMPISSRLVVNQAALKLKRAALKPFLDAFERASLGSGA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_STAAS
Sequence: MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVSVYLEEMDQRNAVIIK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.