PharMolix/UniProtQA huggingface dataset:
Protein: WRN_HUMAN
Sequence: MSEKKLETTAQQRKCPEWMNVQNKRCAVEERKACVRKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLGKVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKLKNFVELTDVANKKLKCTETWSLNSLVKHLLGKQLLKDKSIRCSNWSKFPLTEDQKLYAATDAYAGFIIYRNLEILDDTVQRFAINKEEEILLSDMNKQLTSISEEVMDLAKHLPHAFSKLENPRRVSILLKDISENLYSLRRMIIGSTNIETELRPSNNLNLLSFEDSTTGGVQQKQIREHEVLIHVEDETWDPTLDHLAKHDGEDVLGNKVERKEDGFEDGVEDNKLKENMERACLMSLDITEHELQILEQQSQEEYLSDIAYKSTEHLSPNDNENDTSYVIESDEDLEMEMLKHLSPNDNENDTSYVIESDEDLEMEMLKSLENLNSGTVEPTHSKCLKMERNLGLPTKEEEEDDENEANEGEEDDDKDFLWPAPNEEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQSENVLTDIKLGKYRIVYVTPEYCSGNMGLLQQLEADIGITLIAVDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVALTATASSSIREDIVRCLNLRNPQITCTGFDRPNLYLEVRRKTGNILQDLQPFLVKTSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSSRCRRQIILSHFEDKQVQKASLGIMGTEKCCDNCRSRLDHCYSMDDSEDTSWDFGPQAFKLLSAVDILGEKFGIGLPILFLRGSNSQRLADQYRRHSLFGTGKDQTESWWKAFSRQLITEGFLVEVSRYNKFMKICALTKKGRNWLHKANTESQSLILQANEELCPKKLLLPSSKTVSSGTKEHCYNQVPVELSTEKKSNLEKLYSYKPCDKISSGSNISKKSIMVQSPEKAYSSSQPVISAQEQETQIVLYGKLVEARQKHANKMDVPPAILATNKILVDMAKMRPTTVENVKRIDGVSEGKAAMLAPLLEVIKHFCQTNSVQTDLFSSTKPQEEQKTSLVAKNKICTLSQSMAITYSLFQEKKMPLKSIAESRILPLMTIGMHLSQAVKAGCPLDLERAGLTPEVQKIIADVIRNPPVNSDMSKISLIRMLVPENIDTYLIHMAIEILKHGPDSGLQPSCDVNKRRCFPGSEEICSSSKRSKEEVGINTETSSAERKRRLPVWFAKGSDTSKKLMDKTKRGGLFS
What is the function of this protein?
Multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang.  Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA.  Binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and Holliday junctions.  May play an important role in the dissociation of joint DNA molecules that can arise as products of homologous recombination, at stalled replication forks or during DNA repair.  Alleviates stalling of DNA polymerases at the site of DNA lesions.  Important for genomic integrity.  Plays a role in the formation of DNA replication focal centers; stably associates with foci elements generating binding sites for RP-A (By similarity).  Plays a role in double-strand break repair after gamma-irradiation.
What are the official names of this protein?
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, DNA helicase, RecQ-like type 3, RecQ protein-like 2, Werner syndrome protein.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecQ subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Nucleus, nucleoplasm. Chromosome. Note=Gamma-irradiation leads to its translocation from nucleoli to nucleoplasm and PML regulates the irradiation-induced WRN relocation (PubMed:21639834). Localizes to DNA damage sites (PubMed:27063109).
Protein: CEMA_LEPVR
Sequence: MAKKKAFIPFFDFTSIVFLPWLISLCCNKSLKTWITNWWNTRQCETFLNDIQEKSILEKFIQLEELFQLDEMIKEYPETDLQQFRLGIHKETIQFIKIHNEYRIHTILHFSTNLISFVILSGYSFWGKEKLFILNSWVQEFLYNLSDTIKAFSILLLTDLCIGFHSPHGWELMIGYIYKDFGFAHYEQILSGLVSTFPVILDTIFKYWIFRYLNRVSPSLVVIYHAIND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: HIS3_CHLTE
Sequence: MGENQETQKSFLETVKFDSNGLVPAIVQDHETGKVLMMAWMNLESLKMTLEKKKACYWSRSRNKLWLKGESSGNMQEVHDILIDCDGDTLLLKVSQKGGACHVGYHSCFYRRTVDGESMEICDTLMFDPEEVYGKQS
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_PEDPA
Sequence: MKIDVLTLFPKMVEVPLHESIVGKAIEAGKLNVDVTDFRQYSTNKHGNVDDYPYGGGAGMLLTPQPIFDAMEHVKSQNNQSTGRVILVDPGGKQFNQTMAEDFAKEEHLTFICGHYEGYDERIKTLVDDEVSLGDFVITGGELAALTMIDATVRLLPDILGNKDSAVDDSFSTGLLEFPQYTRPEDFRGLKVPSILLSGNHGKIDEWRRTESLKKTLARRPDLLETAQLTPEDKQILRELQTPDL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y089_BORBU
Sequence: MRSAVLFFFALPFSISLYSSSNKNFPYWILLEKGRQFLYSKSEFSKSNLTHAINYLQEALLRKGVYPEASYYLSVAYGMSGNAILEKLNLYKSFEDRYYLLDESFEKKILFSLAKMAELENNYVDTIDYLNDILNKFSTKKDYYSYHDYSQGENSMSNNELNASFYLTSYLKQVRGAFGIDFTFNLYRFKNYNVIDTHQLLSKVYLHLKAYELSITHGLIAAVGILTRMYDYVCYYEPVYQFKNLRSFVQKINKYKAIKNAFESTDFWEIVYNVAAATYAYSNGNYKFRAIDTWKLVVDLAPRFSPYIAKSRSQIKNSVYLKKN
What are the official names of this protein?
Uncharacterized protein BB_0089.
Protein: NEK5_MOUSE
Sequence: MDNFHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTKEKEASKNEVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQRGVMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYELCTLKHPFESNNFHHLVLKICQGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFLETLIARSLYPEVCSRRIQSHAHMENMAIGPTACWRVSPWSAAYLQRKFEAQQYKLKVERQLGLRPSSVEPHPNEGEKLQSHWEETKFQELQYRKNKMKDQEYWKQLEEIRQQYHNDMKEIKKKMGRELKRVVKFEISLDKCISEEDTVQENEAVDKLNATLSFEDGTKFQEHRCKEEHEDYTDRAFEELCGPEAEGFFQDVIAAENRRQWDAGAPHTLLRIMAMADVTSTCPTMPDDGQVIVMEGSVENGKQWWLDVPGTPCALAAECACSGSLSASKGETVMIKPQLPKEDQEKVEIATGIMVDDEQLEPGSDEDDIKFEESEDELRSEIIESLEKLAASTEEAEQAPSSSKNAEEPGEKEKTNLPVKKLQ
What are the official names of this protein?
Serine/threonine-protein kinase Nek5, Never in mitosis A-related kinase 5, NimA-related protein kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Protein: ARSC_BACC7
Sequence: MENKKTIYFLCTGNSCRSQMAEAWGKKYLGDNWNVYSAGIEAHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVVTLCSHADSVCPSTPPDVNRVHWGFDDPAGKEWSEFQRVRDEIGERIKRFSETGE
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KXDL1_MOUSE
Sequence: MDTPDSASRVFCGRFLSMVNTDDVNAIILAQKNMLDRFEKTNEMLLNFNNLSSVRLQQMSERFMHHTRTLVDMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEGSFLEDEDEDPIPPSITTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHIQPGSPAINGHRQTDDEEETHEE
What is the function of this protein?
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (By similarity).  May also be involved in the biogenesis of lysosome-related organelles such as melanosomes (PubMed:22554196).
What are the official names of this protein?
KxDL motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the KXD1 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: SYN_STRTD
Sequence: MSKQLVSIIDVPKHIGEEITIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFIEKFGEEEGLEKFDTIKHLSQETSIYVTGMVKEDERSKFGYELDITDIEVIGESQGYPITPKEHGTDFLMDNRHLWLRSRKQMAIQQIRNAIIYATYDFFDKNGFIKFDSPILSSNAAEDSTELFETDYFGTPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSFLSHDESLDLQEAYVKALIQGAIDRAPQALEILERDVDLLKKYIAEPFKRVSYDEAIDLLQAHEKDEDTDYEHLEHGDDFGSPHETWISNYFGVPTFVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDDYDALVAKMEELGMDRSEYEFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIKP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_GEOSM
Sequence: MTDKVRLTTMVQAAGUAAKLGPAGLEEAIHDITRSDDPNLIVGVEGAEDAGIYRIGDNLALVETTDIITPLVDDPFTFGRIAAANALSDVYAMGGRPVTAMNLAFFPACSLPTKVLAAILAGGSDALKEAGACLVGGHTVEDNELKFGLAVTGLIDPARVVRNCTARPGDLIVITKPLGTGIVSTAIKAEMVEPVLEAEATRWMTILNAQAAELMVACRATAATDVTGFGFIGHACEMALGAKVTFRIELARVPVIPGVPALIDDGLVPAGCYRNRQHYEQHVSGKSGDPLLPLFDPQTSGGLLITFAPDDARTFLSRAGEEGLFAACIGEVEPAGGTPLVFV
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: PRPE_GEOTN
Sequence: MHIDIIGDIHGCYREFTALTEKLGYVWDKGIPIHPDGRKLGFVGDLTDRGPESLKMIDIVCALVDRKLAHYVPGNHCNKLYRFFLGRNVQVTHGLETTVAEYRALPPSEQEMIRRKFIRLYEGAPLYAVLDEGRLVIAHAGIRHDYIGRMDKKVKTFVLYGDITGETNPDGTPVRRDWAKRYRGDAWIVYGHTPVEKPRFVGRTVNIDTGCVFGGALTALRYPEMTTVSVPSSMPHVPEKFRTFS
What is the function of this protein?
Asymmetrically hydrolyzes Ap4p to yield AMP and ATP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical], Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the PrpE family.
Protein: CHIB_MAIZE
Sequence: PQLVALGLALLCAVAGPAAAQNCGCQPNVCCSKFGYCGTTDEYCGDGCQSGPCRSGRGGGGSGGGGANVASVVTSSFFNGIKNQAGSGCEGKNFYTRSAFLSAVKGYPGFAHGGSQVQGKREIAAFFAHATHETGHFCYISEINKSNAYCDPTKRQWPCAAGQKYYGRGPLQISWNYNYGPAGRAIGFDGLGDPGRVARDAVVAFKAALWFWMNSVHGVVPQGFGATTRAMQRALECGGNNPAQMNARVGYYRQYCRQLGVDPGPNLTC
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Endochitinase B, Seed chitinase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: UC19_MAIZE
Sequence: NGRRYTTYGCSPPVT
What are the official names of this protein?
Unknown protein from spot 406 of 2D-PAGE of etiolated coleoptile.
Protein: RNZ_PYRHO
Sequence: MIEVIFLGTGGIKPTPERNVPSIAIKIGGEIILFDVGEGTLRQMEIARISPMKIKRVFITHFHGDHYLGLPALIQTMSLWKRKDPLHIYGPEGSSTFLQNLLNSGYFAPSFDILVHEISGKSRLKFKEYEVWAFEVSHGVPALGYVFKEKDKRGNFNLKKIKELGLEPGPWMKELERQKIIEINGKIVRLLEVTGPKKRGAKVVYSGDTEPCDEVIEFSRRGTLLIHEATYVNEEDRKDSYHTTIEEACEIWKKSKARKLVLFHRSPRYSFKEYKEKALSICPQAIIPRDFDRIAIEGAGDVLFKIR
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: Y6292_STRAW
Sequence: MSTGIETAGVPDAVIPELVIISGMSGAGRSTAAKCLEDLGWFVVDNLPPALIPTMVELGARSQGNVARIAVVVDVRGRRFFDNLRESLADLESKNVTRRIVFLESSDEALVRRFESVRRPHPLQGDGRIVDGIDAERELLRELRGDADLVIDTSSLNVHELRAKMDAQFAGDEEPELRATVMSFGFKYGLPVDADLVVDMRFLPNPHWVPELRPFTGLNEEVSAYVFNQPGAKEFLDRYAELLRLIAAGYRREGKRYVTIAVGCTGGKHRSVATSEKLAARLAAEGVETVVVHRDMGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SAV_6292.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: HIS4_DEHMC
Sequence: MFKRGVKIEIIPAIDILGGRCVRLFQGDYAQETVYSSDPVGTAMRWQSLGAPRLHVVDLDGAADGQSVNFELIKEIANSALIPVEVGGGIRSMETVKKLLVAGVDRVILGTAAVENPELVKEICARYADSVAVSIDARNGKVATRGWVTNTEIDALELARSMKKLGIRRFIYTDISRDGTLSEPNFAAIRDLISAINVPVIASGGVSSLSHLRLLKDIGAEGAIVGKAIYTGDLNLKRAFEDLS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_HALVD
Sequence: MTEEIVVIPGDGIGAEVIPAAVDVLKAVGDFEFVEADAGDHVKEETGEALPQETYDLAAEADATLFGAAGETAADVILPLRTAVDSFVNVRPAKAYPGVDALRPETDLVFLRENTEGVYSGHEDRLSEDLSTLTRVVTTSASERLAEYACDYVGGEGGSFQVAHKANVMRETDGRFRDAAVAVADERGVETEEVLMDAFATRVCLDPTQFDTIVCPNLAGDVLSDLAAGLVGGLGLLPSANIGPDAALFEPVHGSAPDIAGEGIANPAATILSAAMLLDYLDHEAEADRVRSAVEGVLADGPRTPDLGGDASTEDVTAAILDRL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK27_NEOYE
Sequence: MAHKKGSGSTRNGRDSNSKRLGVKKYGGEQVTAGNILIRQRGTKVKPGQNVGKGKDDTLFSLIDGFVLFEKSNQKQKTISVYSAKK
What are the official names of this protein?
50S ribosomal protein L27, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUVB_PSEPK
Sequence: MIEADRLIAASGRDREEVQDRAIRPLSLDEYIGQPVVREQMALFIQAARGRGESLDHTLIFGPPGLGKTTLANIIAHEMGVSVKSTSGPILERPGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYNDKDLSTIVSRSANILGLAIEDQGAYEIARRARGTPRIANRLLRRVRDYAEVRGKGQITKAVADMALNLLDVDERGFDHSDRRLLLTMIEKFDGGPVGVDNLAAAISEERHTIEDVLEPYLIQQGYIMRTPRGRVVTRHAYLHFGLNIPGRLGEGGDFSEPGDE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GACO_DICDI
Sequence: MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacO, GTPase activating factor for raC protein O.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LITA_LATHA
Sequence: LVIETIENIATKLSISISFKTDVTQTLIDITEIDLNAQDKILIRNTNAVINIKSKVGLTPLHLATLQNNLSVSKGAYLNDGDANGMTPLHYAAMTGNLEMVDFLKWTPLHLAILFKQLVIELLAKTFFDLAIENGRLNIVAFAVEKYIAAR
What is the function of this protein?
Insecticidal presynaptic neurotoxin that induces massive neurotransmitter release at insect (but not vertebrate) neuromuscular junctions.  Native toxin forms cation-permeable pores (with high permeability to calcium) in lipid membranes locust muscle membrane and artificial lipid bilayers (By similarity).  May bind to insect neurexin-1 homolog, insect adhesion G protein-coupled receptor L1 homolog, and insect receptor-type tyrosine-protein phosphatase S homolog, and induces neurotransmitter exocytosis both by forming tetrameric pores in membranes and signaling via G protein-coupled receptor (By similarity).  Oligomerization is a process independent of divalent cations (By similarity).  The toxin forms channels with 0. 55-0. 58 nm entrance diameter and a relatively small conductance in planar phospholipid membranes (By similarity).
What are the official names of this protein?
Alpha-latroinsectotoxin-Lh1a, Alpha-LIT-Lh1a, Alpha-latroinsectotoxin, Alpha-LIT.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 01 (latrotoxin) family. 02 (alpha-latroinsectotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: RL15E_METJA
Sequence: MGIYKYIREAWKRPKESYVRQLLWERLQQWRREPAVVRIERPTRLDRARALGYKPKQGIIVVRVRVRRGGLRKPRPKNSKKPATLGVNKITMGKSIQRIAEERAARKYPNMEVLNSYWVGEDGKHKWYEVILVDPYHPAIKADPQLNWLCTGKHRGRAFRGLTSAGKKGRGLRNKGIGAEKVRPSIRAHGRRGK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: ATL32_ARATH
Sequence: MMTRVECFNPHRWIILHVAIIIQSKANAQSFSPSPPDLQTGHTPSKTTVFAVLVTLFFLTGLLSVYIRHCARSNPDSSTRYFRNRANDGSSRRGGLDNAVVESFPVFAYSSVKESKIGSKDLECAICLNELEDHETVRLLPICNHLFHIDCIDTWLYSHATCPVCRSNLTAKSNKPGDEDDGVPLAAMRDHVVVDIETVEVAKSHHRRLSSEISGKFPRSNSTGHSMDRFSDGTERFTLRLPDDVKMRLMAVKGRRLKRTRSFDVDLTAEHYCRSGEESSNTIGSGAKSGRVNWPDRWGLTLFVSKSNSGSVRSQKSNGEPLK
What are the official names of this protein?
RING-H2 finger protein ATL32, RING-type E3 ubiquitin transferase ATL32.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYP_HELPJ
Sequence: MLFSKLFAPTLKEPPKDAVLKSPKHPGKAGYIYQIGSGIYNFLPLAKKVLDKIENVTHKRMQEHGAQNILMSFVVLASLWEKSGRLDKYGKELLVFKDRKDNDFVLSPTLEENITEIAANFIKSYKQLPVHLYQIHTKFRDEIRPRFGLVRAREFIMKDGYSFHEDAESLDKEFLNTQSAYKEILSDLGLDFRIVEADSGAIGGSKSREFVVLTECGEDTIVVCQNCDYAANIEIAKRSKRTEPLMSPSALAKFPTPNTTSAPSVAEFFKTEPYFVLKALVNKVIHKDKETLACFFVRGDDNLEETKALNTLNLLGANALELREANEEDLNKAGLIAGFIGPYGLKKHVCYIIFDEDLKEGDCLIVGANEKDFHAVGVDLKGFENLVYADIVQVKESDCCPNCQGALKYHKSLEVGHIFKLGQSYAKSLKASFLDKNGKERFFEMGCYGIGISRLLSVILEQKSDDLGCVWTKNTAPFDVVIVVSNLKDEAQKKLAFEVYERLLQKGVDALLDDRDARFGAKMRDFELIGERLALIVGKQTLESKEFECIKRANLEKQTIKDIELEEKILEMLASE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_LISMO
Sequence: MSKIPVIVIVGPTAVGKTSLSIELAKKLDGEIISGDSMQVYRGLDIGTAKITPEEMDEIKHYLIDVTDPSEPFTAAKFQTETRKWIETIHQAGKLPIIVGGTGLYIQSVFYDYDFGNVSEDKAYRAELEQLNKTLLWQMLEQQDPESAAQIHENNKRRVIRALEVMHLTGKPFSEYQVHNVLNDTYKPLFLGLDLDRALLYERINQRVNLMFEEGLVTEAKKLYDQHLVDVPAVCGIGYKELFPYFEGKSSLEEAKELIQKNSRHFAKRQLTWFRNRMEIDWIQAGVSTTEAEALNKAETFLSVK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GCSH3_AQUAE
Sequence: MGKQEKDLGTAWEYQGCLIPKDLYYDIENQVWVRVNEDGTVTLGLTDVGQTRAGRLLHIRVKPVGTKVKKGKPVATLESGKWAGPVPALVEGEIVEVNPKVVEDPNYINIDPYGDAWIVKIKPTSEETLKRDLSELAHGEKAHEEMKKHIDEWDIVCMRCV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein 3.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ADD_MYCVP
Sequence: MTTPLTFDNIRRAPKALLHDHLDGGLRPSTVLELAEQYGYEDLPAHDADGLATFFRTAAHSGSLVRYLEPFAHTVGVMQNPDALHRVARECVEDLAADNVVYAEVRFAPELHIDGGLSLDAVVDAVLAGFADGEKAAAADGRAITVRCLVTAMRHAARSREIAELAIRFRDKGVVGFDIAGAEAGYPPSRHLDAFEYMRSNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIEIDADGNAKLGRLASLLRDKRIPFEMCPSSNVQTGAVASIAEHPFDRLARLRFRVTVNTDNRLMSDTSMSMEMLRLVEAFGYGWSDLERFTINAMKSAFIAFDERLAIIDEVIKPRYAVLVG
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: Y2972_CHRSD
Sequence: MAIHEWPEGERPREKLLALGASALSDAELLAIFLRVGVKGRSAVDLARDLLLAFGGLRPLLEADLARFCAEHGLGEAKYVQLQASLELSRRHLGSLLERGAALTSPTLVRRFLTSQLRHLPHEAFAALFLDTQHRVIRFETLSKGTLDSASVYPREVSRRALALNAGALIFAHNHPSGVAEPSDADRRITQRLSDALGLFDIRVLDHFVVGDGEVVSFAERGWL
What are the official names of this protein?
UPF0758 protein Csal_2972.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: TSR2_XENLA
Sequence: MAARSVDSRGLFREATKAVLGSWPVLQIAVENGFGGSHSQEKAEWMVGAIDQYFSSNADLEQYEVEDSIMGMMNDEFDTIVEDGSQALVAQQLCVLFSQCRQGETAAVQAKIAQLAQKKYDVRAKVQEVTPSDDEEESSDDEEEAMDCENTPGSSSAASLSGALGPSSAPKKEEEPEDDGWTVVRRKKK
What is the function of this protein?
May be involved in 20S pre-rRNA processing.
What are the official names of this protein?
Pre-rRNA-processing protein TSR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the TSR2 family.
Protein: GLSA_SALNS
Sequence: MARAMDNAILETILQRVRPLIGQGKVADYIPALASVEGSKLGIAICTVDGQHYQAGDAHERFSIQSISKVLSLVVAMRHYPEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRALCGVSDITYDATVARSEFEHSARNAAIAWLMKSFGNFHHDVPTVLQNYFHYCALKMSCMELARTFVFLANQGEAFHLDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDPAGNSLAGIAALEQLTQTLGRSVY
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.