PharMolix/UniProtQA huggingface dataset:
Protein: TRMFO_SYNWW
Sequence: MQQVNVIGGGLAGCEAAYYLAQKGIRVRLWEMRPQKATAVHRTADLGELVCSNSLKSDQPNTAQGLLKREMRILGSLLLSCAEKARVPAGSALAVDRELFAGLVSQAILACPSIELCREEVNRVPTGELSIVASGPLTSEALAADLRRITGEENLFFYDAVAPSISADSLDMNKIFRASRYGKGSADYLNCPLDREEYESFYENLINADIKAGHSIDKSLFFNACMPAEVIARRGKDALRYGPMRPVGLEIPGSSKRAYAVLQLRQEDKAGTIYGMVGFQTRMRWGEQERIFRLIPGLEQAEFVRYGVMHRNTYINSPKLLWPSLQCKKRPEIFFAGQITGVEGYMESAATGIIAGINAARWLQGKALLTPHKATIIGALLDFISSSSSQDFQPMNANFGLLPPMEPPIKDKAKRYLAYVERALNKMGEFSESLLN
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_ANAMM
Sequence: MPIYEFAFIAQQGLTQYELEGLSKGLSALLVKIGAELVKYEYWGLLDFAYSIAKNNKGHYCMMYIRAEPAAMDEFRRRVRLNEDVLRFLCLKVDKVCEGKSAMMGSDQD
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: INTZ_ECOLI
Sequence: MSKTPLTAKAIDAAQPQDKPYKLTDSLTPGLFLLVHPNGSKYWRFRYWLNKREFLQAIGVYPLITLKEARRRATESRSLIANGINPVEQARKEKAIDALNMAAGFKKVAEDWFATRVGGWSESYAKQVRSALEKDVYPVLGKRSIVDITARDVLALLQKKERTAPEQARKLRRRIGEIFKFAVITELVTRNPVADLDTALKARRPGHNAWIPISEIPAFYKALERAGSVQIQTAIRLLILTALRTAELRLCRWEWINLEDATITLPAEVMKARRPHVVPLSRQAVELLQDQFTRSGYSAFVFPGRFMDKPLSASAILKALERIGYKSIATGHGWRTTFSTALNESGRYSPDWIEIQLAHVPKGIRGVYNQAAYLKQRRAMMQDYADAIDSILAGNGNPLEPE
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
What are the official names of this protein?
Prophage integrase IntZ, Putative prophage CPZ-55 integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: PYRG_ERWT9
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLKVTIMKLDPYINVDPGTMSPTQHGEVFVTDDGAETDLDLGHYERFIRTRMSRRNNFTTGRIYSEVLRKERRGDYLGATIQVIPHITNAIKERIIEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVDVGREHTMYMHLTLVPYMAAAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGMLKSQGLDDYICKRFSLNAPEANLQEWEQVIYQEANPGGEVNIGMVGKYVELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVELLKDLDAILIPGGFGYRGVEGKLMTAQYARENNIPYLGICLGMQVALMEFARNVAHMEGANSTEFVPDCKYPVVALITEWRDEEGNVEQRSEQSDLGGTMRLGSQQCQLTDGSLVRQLYGSDTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIVEIPNHPWFVACQFHPEFTSTPRDGHPLFSGFVKAASEYQKRLAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: GUC2B_CAVPO
Sequence: MGSRTLLGHLSVLAVVLLLLLQGTQSVDIKYQGYQVQLESVKKLKALEEQWVSSPRLQAQDPQPAVCHHPALPLDLQPICTSQEAASILQALRTMDNDECELCVNIACTGC
What is the function of this protein?
Endogenous activator of intestinal guanylate cyclase.  It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.  May be a potent physiological regulator of intestinal fluid and electrolyte transport.  May be an autocrine/paracrine regulator of intestinal salt and water transport.
What are the official names of this protein?
Guanylate cyclase activator 2B.
What is the protein family that this protein belongs to?
Belongs to the guanylin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPPH_ECOL5
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: FLIE_BUCBP
Sequence: MKIQNINNNLYSDDVIPYLSTEKITHPKNFYENFTNALKKTSANERNIFDKINNSQIDESNSSLNDIMVDLQKISISIQFLVQVKNKLVESYQEIMNMQI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: Y2293_MYCTU
Sequence: MGAPLRHCLLVAAALSLGCGVAAADPGYVANVIPCEQRTLVLSAFPAEADAVLAHTALDANPVVVADRRRYYLGSISGKKVIVAMTGIGLVNATNTTETAFARFTCASSIAIAAVMFSGVAGGAGRTSIGDVAIPARWTLDNGATFRGVDPGMLATAQTLSVVLDNINTLGNPVCLCRNVPVVRLNHLGRQPQLFVGGDGSSSDKNNGQAFPCIPNGGSVFAANPVVHPIAHLAIPVTFSRRRDPG
What are the official names of this protein?
Uncharacterized protein Rv2293c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HM24_CAEEL
Sequence: MSEKETPSPVLDVKKEKNEETGIDEEKSSEDDCSKRSKVKSNPSKFSVNSILSPLESLVRVQQQLLKMAASKSGTPGTNAGVPGAFPYGPGRLPGNYFAGPFPGYSGAQPNWYNGNDPRFAAAAALLPCSIDPVRSAINHQFSMSSMSQRRKRRVLFSQAQVYELERRFKQAKYLTAPEREQLANSIRLTPTQVKIWFQNHRYKCKRQEKEKAMSGLGHSEDGSSPPPDNDDDDDKYSIEMDDKDDEEEEESEKPVLKPSGVFGLPYPPNAAAAAAAAAAAFNFPFAAQGPNPAYYMRW
What is the function of this protein?
Probable transcriptional regulator that is required in neural development for the normal formation of sublateral cholinergic motor neuron processes.  Plays a role in regulating the expression of acetylcholine transporter protein unc-17 in the sublateral processes.  In particular, it is required in sublateral motor neurons for a left-right turning behavior that occurs during the lethargus phase of the normal sleep process called 'flipping'.  During 'flipping' animals rotate 180 degrees about their longitudinal axis.
What are the official names of this protein?
Homeobox protein ceh-24.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: A1AT_PAPAN
Sequence: LLLAGLCCLLPGSLAEDPQGDAAQKTDTPPHDQNHPTLNKITPSLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHSEILEGLNFNLTEIPEAQVHEGFQELLRTLNKPDSQLQLTTGNGLFLNKSLKVVDKFLEDVKNLYHSEAFSVNFEDTEEAKKQINNYVEKGTQGKVVDLVKELDRDTVFALVNYIFFKGKWERPFEVEATEEEDFHVDQATTVKVPMMRRLGMFNIYHCEKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENENRRSANLHLPKLAITGTYDLKTVLGHLGITKVFSNGADLSGVTEDAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFIGKVVNPTQK
What is the function of this protein?
Inhibitor of serine proteases.  Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.  Inhibits trypsin, chymotrypsin and plasminogen activator (By similarity).
What are the official names of this protein?
Alpha-1-antitrypsin, AAT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCR5_TRAPH
Sequence: MDYQVSSPTYDIDYYTSEPCQKVNVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSP1_XENLA
Sequence: MKGIFLLLMLVMPQTHQAAESGNDDNSVFDLFELTGYNRKAGSRKPQGLHLVKGPDPSSPAYRIEDADLIPPLPEDKFQDLLDAIRADRGFILLATLRQAKKSRGALLSVERKDGGGHIFSLISNGRARTLDLSLSGERKQQVVSVEDAVLATGNWTNITLFVQEDRAQLYVGCNKMENAELDVPIQKIFTENLASTAHLRVAKGGVKDNFQGVLQNVRFVFGTTLEAILRNKGCLSMTNSVITLDNPVNGSSPAIRTNYIGHKTKDLQAVCGFSCDDLSKLFAEMKGLRTLVTTLKDQVTKETEKNELIAQIVTRTPGVCLHNGVLHKNRDEWTVDSCTECTCQNSATICRKVSCPLMPCTNATIPDGECCPRCWPSDSADDDWSPWSDWTPCSVTCGHGIQQRGRSCDSLNNPCEGSSVQTRSCQIQDCDKRFKQDGGWSHWSPWSSCSVTCGSGQITRIRLCNSPVPQLNGKQCEGEGRENKPCQKDPCPINGQWGPWSLWDTCTVTCGGGMQKRERLCNNPKPQYEGKDCIGEPTDSQICNKQDCPIDGCLSNPCFAGVKCTSFIDGSWKCGSCPPGYRGNGITCKDIDECKEVPDACFTLNGVHRCENTEPGYNCLPCPPRFTGTQPFGKGIEEAKANKQVCKPRNPCADGTHDCHKNARCIYLGHYSDPMFRCECRPGYAGNGIICGEDTDLDGWPNENLTCVDNATYHCLKDNCPNLPNSGQEDYDKDGMGDACDKDDDNDGILDDRDNCQFVYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDRNGEGDACSVDIDGDGILNERDNCAYVYNVDQKDTDKDGVGDQCDNCPLEHNPEQTDSDSDLIGDKCDNNQDIDEDGHQNNLDNCPYIPNANQADHDKDGKGDACDHDDDNDGVPDDKDNCRLVPNPDQTDTNGDGRGDACQYDFDDDSIPDAEDVCPENVEISTTDFRKFQMVPLDPKGTSQIDPNWVVRHQGKELVQTVNCDPGIAVGFDEFSAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQITQTYWDTTPTVAQGYSGLSIKVVNSTSGPGEHLRNALWHTGNTPGQVRTLWHDPHQKGWKDFTAYRWHLTHRPKTGFIRVVMYEGKRVMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDS
What is the function of this protein?
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.  Can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1, alpha-V/beta-3 and alpha-IIb/beta-3 (By similarity).  May play a role in ER stress response (By similarity).
What are the official names of this protein?
Thrombospondin-1, Glycoprotein G.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
What are the subcellular locations of this protein?
Secreted. Cell surface. Secreted, extracellular space, extracellular matrix. Endoplasmic reticulum. Sarcoplasmic reticulum.
Protein: REG1_YEAST
Sequence: MSTNLANYFAGKKDIENEHVNRNASHESNSKSDVKISGNDNDNDEDMGPSVSMAVQAKNDDDFHKSTFNLKRTRSMGLLDEYIDPTKKLLGRSDDLYDNDNEYYDNSSNNSSSNSSDDDYDDGYQEHSTSVSPPPADNDSYLIPQDDNDVVVEPERHVDYLSHEWKESEISNSWKYIILKKKKRDVDLVNAARLENASWRTWAKARNNLKTVSPEVVNWSKDSDVTWLYGPIVRDSEGNAQSEEEHDLERGYGSDDENSKRISMPTKNSKSIAAAPKPILKKRTVTEIIEDNALWKLNEARKHMTEMKHASVIMDPNGNKNVHDDFDALAAQVNAQYYHYPKESNSSVSLKSQHSDKKDNSTIPNPVGENSNGGGDKGEEDLHLKSALHVQNNRSTAQSNKSILENSTNDRKANLDQNLNSPDNNRFPSSTSSSNRDNENNSMGLSSILTSNPSEKSNKPTKNRHIHFNDRVEQCMALRYPASQSEDDESDDENKQYVDVNNNANVTTINNNRTPLLAIQHKSIPINSATEHLNKNTSDDDTSSQSSSSSHSDDEEHGGLYINARFSRRSDSGVHSPITDNSSVASSTTSRAHVRPIIKLLPDTTLNYGSDEESDNGEFNGYGNAVSHNVNTSRGYDYIYDYNSVYTGDTSSFLPVDSCDIVDVPEGMDLQTAIADDNASNYEFNNAVESKEKHVPQLHKASANNTTRQHGSHMLLYDDDNYSSSSDSEQQFIEDSQYNSSDDEEEEDDDDQEVDDNHDEGLSLRRTLSLGKSGSTNSLYDLAQPSLSSATPQQKNPTNFTGGKTDVDKDAQLAVRPYPLKRNSSSGNFIFNSDSEEESSSEEEQRPLPANSQLVNRSVLKGSVTPANISSQKKKALPKQPKASDSSQSFRIVNNTPSPAEVGASDVAIEGYFSPRNESIKSVVSGGNMMDHQDHSEMDTLAKGFENCHINNASKLKDKKVDSVQTTRKEASLTDSSNESLHKVVQNARGMASKYLHSWKKSDVKPQENGNDSS
What is the function of this protein?
Involved in RNA processing and negative regulation of glucose repression.  Regulates the level of two antigens, P43 and P70.  Binds to protein phosphatase type 1.  Functions with REG2 and SNF1 protein kinase to regulate growth.  Might regulate SNF1 directly or indirectly.
What are the official names of this protein?
Resistance to glucose repression protein 1, Protein HEX2, Second-site suppressor of the rna1-1 mutation 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLUE_ECOL6
Sequence: MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPENQPTRVILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVEEPAWLWPRNPPIRERKSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWRDATD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase E, rRNA pseudouridylate synthase E, rRNA-uridine isomerase E.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: METK_THIDA
Sequence: MQKDFIFTSESVSEGHPDKMADQVSDAVLDAILTQDKHARVACETLLTTGLCVIAGEITTTAVIDYNQIARQTIKRIGYDSSDIGFDYNTCSVLVTVGKQSPDIAQGVDRAHDDYLDQGAGDQGLMFGYACNETPVLMPMPIHLAHRLTERQSELRKDGRLPWLRPDAKSQVSIRYVDGKPHSIDTVVLSTQHDPEVSHAQLSEAVIEEIIKPVLPKDMLSADTRYLVNPTGRFVVGGPMGDAGLTGRKIIVDTYGGASPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADKCMVQVSYAIGVAKPTSLMVDTFGTGKIPEAKIVELIQAHFDLRPKGIVNMLDLLRPIYTRTASYGHFGRDEPEFTWEVTDKAAELKAAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y013_OSHVF
Sequence: MKLVFIFATAAIMGVVVYGQGRDAGDRGKRSLSDDFISTLQELKEAMDDLPSIYAIINKHGVNICEPCSRLCDNVADTHVVCKRCRRCIGRGGIHGAVAFGMRDE
What are the official names of this protein?
Uncharacterized protein ORF13.
Protein: RF1_SHEB9
Sequence: MKESVIRKLEGLLERNEEVMALLGDASVISDQDRFRALSKEYAQLEDVVAGFKAYQQAQVDLDSAKEMLEEDDAEMREMAQEEMKAAKAKLEHLEDELQILLLPKDPDDDKNAFVEIRAGAGGDEAAIFAGDLFRMYSRYAEANRWQIEIMSCNEGEHGGFKEVIMKVSGDGVYGKLKFESGGHRVQRVPETESQGRVHTSAVTVVVLHEVPEAEAISINPADLKVDTFRSSGAGGQHVNKTDSAIRITHIPTGIVVECQDQRSQHKNRAQAMSVLAARIQAVEDEKRRSAEESTRRSLVASGDRSERVRTYNFPQGRVSEHRINLTLYRLNEVMEGDLDAILLPLMQEHQADQLAALADEQG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D5FAD_REBSA
Sequence: MPPRDSYSYAAPPSAQLHEVDTPQEHDKKELVIGDRAYDVTNFVKRHPGGKIIAYQVGTDATDAYKQFHVRSAKADKMLKSLPSRPVHKGYSPRRADLIADFQEFTKQLEAEGMFEPSLPHVAYRLAEVIAMHVAGAALIWHGYTFAGIAMLGVVQGRCGWLMHEGGHYSLTGNIAFDRAIQVACYGLGCGMSGAWWRNQHNKHHATPQKLQHDVDLDTLPLVAFHERIAAKVKSPAMKAWLSMQAKLFAPVTTLLVALGWQLYLHPRHMLRTKHYDELAMLGIRYGLVGYLAANYGAGYVLACYLLYVQLGAMYIFCNFAVSHTHLPVVEPNEHATWVEYAANHTTNCSPSWWCDWWMSYLNYQIEHHLYPSMPQFRHPKIAPRVKQLFEKHGLHYDVRGYFEAMADTFANLDNVAHAPEKKMQ
What is the function of this protein?
Fatty acid desaturase that introduces a cis double bond at the 5-position in 20-carbon polyunsaturated fatty acids incorporated in a glycerolipid that contain a Delta(8) double bond.
What are the official names of this protein?
Acyl-lipid (8-3)-desaturase, AN Delta(5)-fatty-acid desaturase, Acyl-lipid 5-desaturase, Delta-5 desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TTC12_MACFA
Sequence: MDADQEKDLQKFLKNVDEITNLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQEEDECRTTLNKTVISPPQTAVKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKDKGNEAFAEGNYETAILHYSEGLEKLKDVKVLYTNRAQAYMKLKNYEKALVDCEWALKCDEKCTKAYFHMGRANLALKNYSVSRECYKKILEINPKLQTQVKDYLNQVDLQEKADLQEKEAHELLDSGKNTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQTLFRMHDGFSIISDNEVVRRCFSTAGKDAIEETVCVSVLKLWQAVCCGNEENQRVLVMHPDRARLLATLLSSKVLAIRQQSLALLLQLAQTESGRSLIISHLDLTRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPAVTSVLKTDPKVSSSSALCQCIAIMGNLSAEPATRGHMAACEEFGDGCLSLLARCEENVALFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALQAGVVKKKKKKKKKKKKK
What is the function of this protein?
Cytoplasmic protein that plays a role in the proper assembly of dynein arm complexes in motile cilia in both respiratory cells and sperm flagella.
What are the official names of this protein?
Tetratricopeptide repeat protein 12, TPR repeat protein 12.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPS_KLEPN
Sequence: MSTAKLVKSKATNLLYTRNDVADSEKKATIELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALTEHLDTMAERAVQLGGVALGTTQVINSKTPLQSYPLDIHHVQDHLKALADRYAVVANDVRKAIDEAKDEDTADIFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP14_HUMAN
Sequence: MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAAATAPTTAATTAATAAQ
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:11089964).  SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (PubMed:11089964).  The complex of SRP9 and SRP14 is required for SRP RNA binding (PubMed:11089964).
What are the official names of this protein?
Signal recognition particle 14 kDa protein, SRP14, 18 kDa Alu RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the SRP14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_HELP2
Sequence: MANITTKETPKITPDLLKNPYQKIINASASVFDEKHGRSFFSPQFYEKIEPYLKEVLTHPIDLECDLNTAKKKNRLTPLKQLFKACFNTEEILIVNNNTSAVFLIANALAQEKEIVVSYGELVGGDFNLKDILLSSGARLHLVGNTSRTYLRDYRLALNENSKMLFKTHNPAFKKDTPFKDLQALAKEHDLIDYYNLGDVDLLDRTALEEVLALKPSLLSFSADKSFNSVQAGIIMGQKEWVETLKNHPLYRALRVDKITLTLLFHSLNAWVNHQEEITIHALLHQTKDALLQKALKLYALLKPLELNVSIASSFSKIGNLFGRELESFCVKIQSKNTRALNGEKLYLRLFQKGVITRISCEFVCFEVFSLNEKDFEKIALVLEEILNKA
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_THERP
Sequence: MEFETVIGLEVHAQLLTRSKMFCGCSADYAGAPPNTHVCPVCLGLPGSLPVINRRAVEMTVMTGLALGCRIPPYSKFDRKNYMYPDLPKGYQISQYDLPLCVDGALEFLVDGQRRRVRIRRVHLEEDTARLVHRTVAGESYSLVDMNRSGVPLIEIVTEPDLHSPEEARLFLQSLRQVLRYLGVSTGNMEEGAFRCDANISQRTVDGQQQWPKAEIKNLNSFRSVERALAYEEQRQRAAIRRGERLVQETRGWLEDQGITVTQRAKEYPDDYRYFPEPDLPPIFLTEDDLARIRAAMPELPLARWERFQVEYGLGPQEAALLTEERAVADFFEACVAGDRTLAREAANWITGELFALMRERGCGISEVGVQPRQLRQLIELVQRGTISTLTAKELLGAVSETGTDPEVLVAERGLAQVSDEAQLRAIVQRVLAENPKAVADYRKGKTAAIGFLLGQVNRALAGRANPAVARRLLEEALQQPVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: VATA_PYRIL
Sequence: MSGKIEYISGPVVKADLPGARLYELVFVGEIKLFGEVVRVQGDKAFIQVYEDTTGLKPGEPVVRTGEPLSAWLGPTIMGKIYDGVQRPLKNIEEISKSPFIARGVGYDQAPPLDLKAEFDFKPNVKPGEEVYPGDVLGSVKETELITHYILYPPLPEYVPGTVEWIADGKYKVDDVIARIKTKRGVIEVKMWHKWPVRRPRPFREKLPPVEPLITGVRTIDTMFPIAKGGTAAIPGPFGSGKTVAIRTLSMYAQSRIIIPVLCGERGNEAADALQGLLKLKDPNTGRPLLERTTIIVNTSNMPVAAREASVYMGTTIGEYFRDQGYDVLVLADSTSRWAEAMREVALRIGEMPSEEGYPAYLPTRLAEFYERAGRVVLMGSKERIGSLTIAASVSPPGGDFTEPVTSNTLRFIGAFWPLSPRLAYSRHYPAIDWLLAFSRYVDTVEVWWSKNISPDWRKIRDTLQSILVKEAELQEIVRILGTEALSEYEKHILNVAYMIREGFLKQDAYNPVDTPSSPIKQYLLMKAIYAYYEEGLKAIEAGIPASVLRELETVKRLPRLRMEITNDVAKEELTKFIEMLISEIRTTISKRQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: PFDA_META3
Sequence: MNEELQQQYYQLEMYGQQVQKLQEELEKIELMKMELLKSIDSMEGLKDSEDILIPLGGGAFIKAKAMDTKKVIMGAGADVFLEKDISDVVVDFNKSIEDLDKAGSMIIAKIEETAKVAEQMQKDLEEKVQAMEGQMGGAPTLQM
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOL12_BOVIN
Sequence: MGRNKKKRDGDDRRQRLILSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQKKLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLPTPEQGAGSGPEEEVSSMEKPTRALPRKSRDPLLSQRISSLTASLHAHSRKKVKKKRLRRAQDTTKKPPSATRTSKTRRRRLTGKARHSGE
What is the function of this protein?
May bind to 28S rRNA.
What are the official names of this protein?
Nucleolar protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRP17 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MU109_SCHPO
Sequence: MMKLENKLHRVLCSLHQNSISTHKTYVAVAAQDEYVRMGKVSLPRMYAVKPRIQKNFQDNYRFYGTLLCICWLYFFIWYPFALLALMVGVFLSFVMHGLGSLTINQNIRLDPKYSIPGVCAVTLIVIMFLAPVGRLFWSFCIVSSFAGLHCLLTTYENPAGIL
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 109 protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IAA5_ARATH
Sequence: MANESNNLGLEITELRLGLPGDIVVSGESISGKKRASPEVEIDLKCEPAKKSQVVGWPPVCSYRRKNSLERTKSSYVKVSVDGAAFLRKIDLEMYKCYQDLASALQILFGCYINFDDTLKESECVPIYEDKDGDWMLAGDVPWEMFLGSCKRLRIMKRSCNRG
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin-responsive protein IAA5, Auxin-induced protein AUX2-27, Indoleacetic acid-induced protein 5.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.