PharMolix/UniProtQA huggingface dataset:
Protein: CAS2_HALH5
Sequence: MLVLITYDVQTSSMGGTKRLRKVAKACQNYGQRVQNSVFECIVDSTQLTSLKLELTSLIDEEKDSLRIYRLGNNYKTKVEHIGAKPSIDLEDPLIF
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).  Functions as a dsDNA-specific endonuclease, acting on circular and linear DNA; has no activity on ssRNA or ssDNA.
What are the official names of this protein?
CRISPR-associated endonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: ADH4_YEAST
Sequence: MSSVTGFYIPPISFFGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERDLNVAIYDKTQPNPNIANVTAGLKVLKEQNSEIVVSIGGGSAHDNAKAIALLATNGGEIGDYEGVNQSKKAALPLFAINTTAGTASEMTRFTIISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGLPPALTAATGLDALTHCIEAYVSTASNPITDACALKGIDLINESLVAAYKDGKDKKARTDMCYAEYLAGMAFNNASLGYVHALAHQLGGFYHLPHGVCNAVLLPHVQEANMQCPKAKKRLGEIALHFGASQEDPEETIKALHVLNRTMNIPRNLKELGVKTEDFEILAEHAMHDACHLTNPVQFTKEQVVAIIKKAYEY
What is the function of this protein?
Reduces acetaldehyde to ethanol during glucose fermentation.  Specific for ethanol.  Shows drastically reduced activity towards primary alcohols from 4 carbon atoms upward.  Isomers of aliphatic alcohol, as well as secondary alcohols and glycerol are not used at all.
What are the official names of this protein?
Alcohol dehydrogenase 4, Alcohol dehydrogenase IV, ADHIV.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MTBB_BACIU
Sequence: MTQILETVDKSRLTVNPLLKNKSELGQFFTPSSISIFMACLFSEDKLNNAKVLDAGAGIGSLTSAFLARLISENIGKADLHLLEIDEMLEPYLSETLALFKDYIEINSQIIIDDFIEWAAYSLLDEESLLAKDKQRFTHAILNPPYKKIKSNSKHRKLLRKAGIETVNLYSAFVALTVDLMSDGGEIVFIIPRSFCNGPYFRHFRQHLLNKTSIKHMHLFESRDKAFKDDEVLQENVISKLEKGTVQEDVKISISTDDSFSVIRSYRYPFEKIVQPNDIEKFIHINTTNEETLIEKHPNVCYSLEELNIEVSTGPVVDFRVKENLREMPGEGTVPLFYPNHFVGTSLEYPKMMKKPNAIIRNEKVEKWLYPNGHYVVVKRFSSKEEKRRIVAGVLTPESVNDPVVGFENGLNVLHYNKSGISKEVAYGLYAYLNSTPVDKYFRIFNGHTQVNATDLRTMKFPSRDILISLGKWVIENIENVGQVEIDSKLEELLLNDRGNA
What is the function of this protein?
A beta subtype methylase that recognizes the double-stranded sequence 5'-CTGCAG-3', methylates A-5 on both strands, and protects the DNA from cleavage by the BsuBI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.BsuBI, M.BsuBI, Adenine-specific methyltransferase BsuBI, Modification methylase BsuBI, Type II methyltransferase BsuBI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: EPMA_HISS2
Sequence: MSLNEQWQPSASIQNLLARAKIIADIRRFFTERGLLEVETPVLSEFGVTDVHLSTFSTAFTSPFMEKSKTLWLTTSPEYHMKRLLAAGSGAIFQLCKVFRNEESGKKHNPEFTMLEWYRPHFDMHRLINEVDDLLQQTLDCEPAEMASYQFVFQEHVGIDPLSAPINELIEKARECHLDGAENEDRDTLLQFLFSTLVEPNIGQNKPIAVYHFPATQAALAQISSEDHRVAERFEFYYKGIELANGFNELTDAQEQEHRFNQDNRLREQLGLPQHEIDHRFLGALQAGLPNTAGVALGVDRLIMLALGAENISEVISFNIDCA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: RUTF_STAND
Sequence: MARSAPLDETNSGAAKAPAISREQYRDAMARLGAAVTIVTTDGPGGRAGFTASAVCSVTDSPPTLLVCLNKSSSAAHAVHANGVVCVNTLAAGHEALSNLFGGRTPPEERFAAGQWHTSATGAPILVGAVVAFDCRIVKTVEVGTHDVLFCEVVGLAEGGGREGLIYFSRRYHAVAGTPEG
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: SLB_ECHCA
Sequence: MGRFISVSFGLLVLLLSLSGTGANCLPDWSVYEGYCYKVFKERMNWADAEKFCTKQHKDGHLVSFRNSKEVDFVISLAFPMLKNDLVWIGLTDYWRDCNWEWSDGAQLDYKAWDNERHCFIYKNTDNQWTRRDCTWTFSFVCKCPA
What is the function of this protein?
Binding of echicetin to glycoprotein Ibalpha (GP1BA) receptor on platelets alone results in inhibition of platelet aggregation, while binding to both GPIba receptor and IgMk promotes platelet aggregation and signal transduction.
What are the official names of this protein?
Snaclec echicetin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYE2_WOLTR
Sequence: MPNIVTRFAPSPTGFLHIGGARTALFNWLYAKHHGGRFLLRIEDTDRKRSTQEAIDAIINGLKWLGVSYDGEIVYQSKRIERHIEVANLLVEKGKAYCCCCPEDKVAEKKAKAREERKIYKHKCTSVIPDAKPVVRFNVPDSQEIIVDDKIYGHIKVNSDQLDDMVILRSDNTPTYIFAVVVDDHDAGITDIIRGSDHLTNTFKQVLIYQALDFDIPRFAHVPLIHGRDGNKLSKRHGATSVCDYEKMGILPKAMRNYLLRLGWSHGNDEIISNEQAVKWFNLESIGRSPARLNFKKLEHLNNHYINNMSNEDILTLMLGESTLTNKKKNYLLQGLTELKKRANYLTELLDLAQFYIKDPPFDLSEEAEQVVKSNLDIIKLLASFLSNIGDKNWNKGFLSSQVKEFSKLHSAKISDIYHSLRAPITGVMDAPGIIDIMIILGKDECIRRLQAV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL451_MIMIV
Sequence: MRIISWDVGVIYLAYCVLEYVLSKNKEVIINIIDWNIINLMENNRLVINCCGMKKGNTICDKKASYCLRTPDKKLFGYCKTHLTQYNINWSIQDTEKMFTKISKPDNTCTFLKKTGDFCGKKATYKYKNNKSTNYYCNVHYKSELKNRTKEFSPQPIKNTIVKKYPTAQLQYNLIKKLDKLSKHFAMLGIERVVIENQPSQKNPKMKSIASTLFDYFLIRGFCDKIHNIDIKLVRYMCPSNKLKVNKDNTLEVFKANKDSKKKYKLTKALGIQYTKQLLNNEQEQLDYLSLFEKKDDLCDAYLQGRYYLEFIMDKTDKNYPIIKCQENKFNKPNNDDLQNESGDDSETESSLSWENIKIEISDDQADYYAKKYNKSVMNKSNKLMMNKSMMNKSESNKKSNRKSNKRSNKNIITL
What are the official names of this protein?
Uncharacterized protein L451.
Protein: ATP6_NAEFO
Sequence: SFFYSLFKGTYNFIYVTIYSYLVDRTKMFFPFFFYLFLFICLSNLVGIVPFSFTITSHLNITFSLSFLVWWATCLLGFYESGLAFIAIFYVKGIPFVLVPFWALIEVISFIFRSVGLSLR
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACYP_BORGP
Sequence: MYKQQYFISGKVQGVGFRFFTEQIANNMKLKGFVKNLNDGRVEIVAFFNTNEQMKKFEKLLKNGNKYSNIENIEKKTLDENYPFQFNNFKIYY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: GLYA_HALHL
Sequence: MFSRDMTIAGYDPELAAAIEDERQRQEDHIELIASENYASPRVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVAEQLAIDRAKQLFGADYANVQPHSGSQANAAVFHALLKPGDTILGMSLDHGGHLTHGAKVNFSGKLFNAVQYGINDDGQIDYDEIQRLATEHQPKMVIGGFSAYSQVVDWARLRQIADSVGAYLVVDMAHIAGLVAAGVYPSPIPHADAVTSTTHKTLRGPRGGIILARSNPDLEKKFQSLVFPGTQGGPLMHAIAGKAVAFKEALEPDFKQYQEQVVANARAMARRVIERGYNVVSGGTDNHLFLMDLTPKNLTGKDADAALGRANITVNKNTVPNDPQSPFVTSGLRIGTPAITTRGFKEAEATRLADWICDVLDNMGDESVVERVRGEVEQICREFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHFT_ECOLI
Sequence: MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYMNRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGAIWGVLILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLIAAVVVLMTRVVVVRYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGLSVFEERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLINQAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVDYLSPNPMVAAVLGAVVISAEVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAVAIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA
What are the official names of this protein?
Uncharacterized protein YhfT.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYL_STAES
Sequence: MNYNHKEIEKKWQNYWEENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTQKNIQTFKRQIQELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVVDGVSERGGHPVYRKPMKQWVLKITEYADRLLEDLDELDWPESIKDMQRNWIGRSEGAKVTFKIEQSDQNIEVFTTRPDTIYGTSFLVLSPEHPLVNEITTSDKEQEVKLYQNEASKKSDLERTDLAKEKTGVFTGTFAINPLSGDKLPIWIADYVLSTYGTGAVMAVPGHDERDHEFATKFNLPIIEVIEGGEVQKYAYTGEGKHINSGELDGLENEAAISKAIELLESKGAGEKKVNYKLRDWLFSRQRYWGEPIPIIHWEDGSMTTVPEDELPLLLPETDEIKPSGTGESPLANIDAFVNVIDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPHNEKMIADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLYNQGMILGEGNEKMSKSKGNVINPDDIVASHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLIITDENSINKKIVDSNNHSLDKVYNQTVKKVTEDFDTLSFNTAISQLMVFINECYKTNEVYKPYIEGFVKMLSPIAPHIGEELWDRLGHENTITYQPWPTFDESLLVDDEVEIVVQVNGKVRAKINIPKDLSKEEMQDLALSNDNVKMSIEGKEVKKVIAVPQKLVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_STAES
Sequence: MLRVALAKGRLLKSFIEYLQQVNQIDIATVLLNRQRQLLLTVDNIEMILVKGSDVPTYVEQGIADVGIVGSDILNGQKYNINKLLDLPFGKCHFALAAKPETSCYKKVATSYVHTATQFFNKEGMDVEVIHLNGSVELSCVVDMVDAIVDIVQTGSTLTANGLVEKKYISEINAKLITNKESYFKQSSEIERLIKQLGVSISYA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_CAMJE
Sequence: MVRKIITYPNPRLFLNSEIVNKFDTELHTLLDDMYETMIASNGVGLAAIQVDIPLRVLLVNIFDENDEQKKEDLLEIINPEIIPLDEEMITCTEGCLSVPDFFEEVKRYNHILLKYQDRFGEFKELEAKGFLAVAIQHENDHLNGHLFIEKISFAKRQKFDKEFKKKKKNHKKEK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: BIOF_PHEZH
Sequence: MPAPMDSLAAFATDKLAALESQSLRRRLRPTRRTDGVCVERGGRRLVSFSCNDYLGLSHHPAVKAAAAAAIESEGLGAGASRLVTGDNPLLATLERRLAALKGAEAACVFGSGYLANLGIIPTFMGAGDIVLVDELAHACIWGGARLSGAQVISFRHNDVDDLTGKLAAARGSARRALVATDGVFSMDGDIAPLDDISRTAQAWDAWLLVDDAHGLGVVGGGVGVGALFPSARIDLSMGTLSKALGAYGAYVCAAQPVIDLIKSRTRTVVYTTALPPAVAAGALAALDIIITEPKRVAAPRLRARRLTRSLGLPTAESAIVPIVLGDAETALAAAADLERQGLLAVAIRPPTVPANTARLRIACSALHTESQIDDLAAALQPWMQA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SYK_PSYA2
Sequence: MSKPNNQNQQNNQEQIPEDANELIAQLQAKLEDIVASGKQPYPNTFKRTDYAQDLQTAFEGISKQEIADNDAKGEKTQVNVAGRVMLNRGAFIVIQDMTGRIQLYVARKELDEETLADIKSLDLGDIVGVSGYIGRSGKGDLYVHIEEMQLLTKALRPMPNKFHGLADVEARYRNRHLDLMTNETTRDTFMVRSQVISGIRKFMLNERFMEVETPMMHPIPGGAVARPFVTHHNALDMPLYLRIAPELYLKRLVVGGFEKVFEINRSFRNEGVSTRHNPEFTMIEFYQAYADYHDLMDLTERLFNELATDILGTTEITYQEEDISLKAPFERLSMSNAIAKYAENFDMARINDRDYLAEYASTTLKQQVKDVFGVGKLQTIIFEETAEHQLRQPTFITEYPAETSPLARRSDDNPEITDRFELFVGGRELANGFSELNDPADQAERFLGQVAEKDAGDDEAMHFDAEYIEALSYGLPPTAGEGIGIDRLVMLLTDSASIRDVILFPHMRRKLEG
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RH5_ARATH
Sequence: MAGQKQELPVSGEPLAVESPMTNKKKKKSKKNKHTEENHEVEEVPQEVTNGVEEELSNKEKKKKRKREEKESEKNKKKDVPEKKLEAEDLGEGESEQQKVVVTGKGVEEAKYAALKTFAESNLPENVLDCCKTFEKPSPIQSHTWPFLLDGRDLIGIAKTGSGKTLAFGIPAIMHVLKKNKKIGGGSKKVNPTCLVLSPTRELAVQISDVLREAGEPCGLKSICVYGGSSKGPQISAIRSGVDIVIGTPGRLRDLIESNVLRLSDVSFVVLDEADRMLDMGFEEPVRFILSNTNKVRQMVMFSATWPLDVHKLAQEFMDPNPIKVIIGSVDLAANHDVMQIIEVLDERARDQRLIALLEKYHKSQKNRVLVFALYKVEAERLERFLQQRGWKAVSIHGNKAQSERTRSLSLFKEGSCPLLVATDVAARGLDIPDVEVVINYTFPLTTEDYVHRIGRTGRAGKKGVAHTFFTPLNKGLAGELVNVLREAGQVVPADLLKFGTHVKKKESKLYGAHFKEIAADAPKATKITFDNSDDED
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DPO3E_TREPA
Sequence: MIYDWVFAVHEHVAFTAFDTETTGLKAEEDRIIEIGAVTFDRKGIIARFSTLIFPDRAIPPDVSKINHITDDMLVNKPRFCEIVSDFSRFIKGTVLVAHNANFDVEFLNAELSLCKKQPLSHKVVDTYAMAQAVFPGLGRHQYRLQNLALQFGLTVHAAHRAEDDARVCMELFTTMIAHHAKQNGHCVNHAQSPTIKKLIQEIQASSTDCSQELF
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity).
What are the official names of this protein?
DNA polymerase III subunit epsilon.
Protein: FLZ17_ARATH
Sequence: MTKISVGLQLVTRDSREKLNNIVIKSSLRLNRSNPNISELCFLKTCHLCNKQLHQDKDVYMYRGDLGFCSRECRESQMLIDDRKELEASTKMMLASYRRCNNGAGKSESRNLFDDLRRRRQLFIVP
What is the function of this protein?
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
What are the official names of this protein?
FCS-Like Zinc finger 17.
What is the protein family that this protein belongs to?
Belongs to the FLZ family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles from the cytoplasm to the nucleus when associated with KIN10.
Protein: QUEC_ECO8A
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCSHCAACNLRANGLNHYLADKPTVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: UREE_BRASB
Sequence: MIRATRVLGQHRWTEAAADSVLLDFDDRHRRRLAMTGTRGLAFVLDLAHATALRGGDALVLEDGRLVEVVAAAEPLLEIRASDPHHLVRLAWHLGNRHLPTQIMAKSLRIRRDHVIEAMVKGLGARVIEIEAPFDPEGGAYAEPSHAQGHDEHDHHHGHDHHHDHGGHEHAHHGHDHGHAHDDHVHDEHCGHGHHHHGHAHAHDRK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAND_SPHSS
Sequence: MPKIIDAKVIITCPGRNFVTLKIMTDEGVYGLGDATLNGRELAVASYLTDHVIPCLIGRDAHRIEDLWQYLYKGAYWRRGPVTMTAIAAVDMALWDIKGKIAGLPVYQLLGGASREGVMVYGHANGTTIEDTVKVALDYQAQGYKAIRLQCGVPGMASTYGVSKDKYFYEPADADLPTENIWNTSKYLRIVPELFKAARESLGWDVHLLHDIHHRLTPIEAGRLGQDLEPYRPFWLEDATPAENQEAFRLIRQHTTAPLAVGEIFNSIWDAKDLIQNQLIDYIRATVVHAGGITHLRRIAALADLYQIRTGCHGATDLSPVCMAAALHFDLSVPNFGIQEYMRHMPETDAVFPHAYTFADGMMHPGDQPGLGVDIDEDLAAGYEYKRAFLPVNRLEDGTMFNW
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.  Has no detectable activity with a panel of 70 other acid sugars (in vitro).
What are the official names of this protein?
D-mannonate dehydratase, ManD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: Y027_SIFVH
Sequence: MEEFIIKIAGTKGISNFKSYHFSIISNYENFFNFILPKDVKDVLVVLPFDEEKTKTIKHAITNARSNVSVTIMYSGKIRDEMIIGWRT
What are the official names of this protein?
Uncharacterized protein 27.
Protein: SYDND_ARTS2
Sequence: MLRTHDLGSLRSEHIGQTVTLAGWVGRRRDHGGVAFVDLRDASGVSQVVVREEEVFHGLRNEYVLQVIGTVSQRPEGNENPALATGQIEVIAEKVTILNTSDPLPFQIDEHVEVGEEARLKHRYLDLRRPGPARNMRLRSEANRVARELLHRDGYVEIETPTLTRSTPEGARDFVVPARLAPGSWYALPQSPQLFKQLLQVGGFEKYYQIARCYRDEDFRADRQPEFTQLDIEASFVEQDDIISLGESIVKALWQLIDVEIPTPIQRITYADAMARYGSDKPDLRFGLELTELTEFFKDTNFGVFKAPYVGAVVMPGGASQARRALDAWQEWAKQRGAKGLAYVLFKEDGELAGPVAKNLTDTERAGLADAVGAKPGDCIFFAAGEKTPSRALLGAARVEIGHRTGLINPADWAFCWVVDAPMFEPAAAAVASGDVAVGAGQWTAVHHAFTSPKPEFMDSFDKDPESALSYAYDIVCNGNEIGGGSIRIHERDVQERVFELMGLDKADAETKFGFLLEGFKFGAPPHGGIAFGWDRVVALLAGVESIRDVIAFPKSGGGYDPLTQAPAPITAQQRKEAGVDFKPEAKKADPGATKA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRA_AGRFC
Sequence: MSELKTISIRGAREHNLKGIDLDLPRNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLEMMQKPDVDQIDGLSPAISIEQKTTSRNPRSTVGTVTEIYDYMRLLFARVGVPYSPATGLPIESQTVSQMVDRILAFEEGTRLYILAPIVRGRKGEYKKELAELMKKGFQRVKVDGQFYEIADVPALDKKYKHDIDVVVDRAVVRPDMAARLADSLETCLKLADGLAIAEFADKPLPPEDTAAGGSANKSLNETHERVLFSEKFACPVSGFTIPEIEPRLFSFNNPFGACPSCDGLGSQQKVDENLIVPEPARTLRDGAIAPWAKSSSPYYNQTLEALGKAFGFKLSSKWTDLSKEAQHAILQGTDDKIEFNYQDGARSYKTVKNFEGIVPNLERRWKETDSAWAREEIERYMSAAPCPACAGYRLKPEALAVKINKLHIGEVTQMSIRKARDWFEVLPENLNAKQNEIAVRILKEIRERLRFLNDVGLDYLSLSRNSGTLSGGESQRIRLASQIGSGLTGVLYVLDEPSIGLHQRDNARLLETLKHLRDIGNTVIVVEHDEDAILTADYVVDIGPAAGIHGGQVIAEGTPQDVMANPKSLTGKYLSGELGVAVPAERRKPKKGREIKVFGARGNNLQNVTAAVPLGVFTAVTGVSGGGKSTFLIETLYKSAARRVMGAREIPAEHDRIDGFEFIDKVIDIDQSPIGRTPRSNPATYTGAFTPIRDWFAGLPEAKARGYAPGRFSFNVKGGRCEACQGDGVIKIEMHFLPDVYVTCDVCHGKRYNRETLDVTFKGKSIADVLDMTVEEGVEFFAAVPAVRDKLQSLFDVGLGYIKVGQQANTLSGGEAQRVKLAKELSKRSTGRTLYILDEPTTGLHFHDVNKLLEMLHALVEQGNSVVVIEHNLEVIKTADWIIDIGPEGGTGGGEVVATGTPEDIVKVERSYTGHFLKELLDRRPAGKREAAE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H33_TETPY
Sequence: MARTKQTARKSTGVKAPRKQLATKAARKSAPVSGGVKKPHKFRPGTVALREIRKYQKTTDLLIRKLPFQRLVRDIAMEMKNDIRFQSQAILALQEAAEAYLVGLFEDTNLCAIHARRVTIMTKDMQLARRIRGERF
What is the function of this protein?
Macronuclear replacement variant which replaces conventional H3 in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  Functions redundantly to H3. 4.  H3. 3 deposition into chromatin is mainly transcription-associated and DNA replication-independent, but it can also enter a replication-coupled pathway.  Although not essential for vegetative growth, minor H3 variants are required for producing viable conjugation progeny by affecting late developmental stages of conjugation (By similarity).
What are the official names of this protein?
Histone H3.3, H3.2, Minor histone H3 variant, hv2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes mainly to the large, transcriptionally active, somatic macronucleus (MAC) and only faintly to the small, transcriptionally inert, germ line micronucleus (MIC).