PharMolix/UniProtQA huggingface dataset:
Protein: PORED_CAEBR
Sequence: MLENLWEVRQALPIYLLTATIGLAVSCCFTLICPHVCRLIPALTTYGKAADQLEENSLVARISVPKKWFKHFYALGLLTLLLCLHCIHSLIHNPDFLPTIPIKFLTILTRSYSIPPIAPSTAVLALLLITFHVARRLYETLFVSVYSDSRMNVFHYIVGIVHYIILPISIMCETQGVITKKEIFHVSVDDITLTQWAGAVLFWVCNWKQHQIAEQIANTRKGPRGLIRNYAYGICFGRWFNLVSCPHFLFEICIYLSLLLVIPTAYVYRFVVLFVCVNQTFAALITHSWYHKTFPKYPKTRKALIPYVL
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol.  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity).
What are the official names of this protein?
Polyprenol reductase.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MESD_RAT
Sequence: MAASSWLRAVLLFLCASDLLLLSPPEAYATDTPGEAITPPRKKKDIRDYNDADMARLLEQWEKDDDIEEGDLPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTISGNPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVNQDRCAEVTLEGQMYPGKGGGSKEKNKTKPEKGKKKEGDPKPRASKEDNRAGSRREDL
What is the function of this protein?
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs).  Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane.  Essential for specification of embryonic polarity and mesoderm induction.  Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4.  May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.
What are the official names of this protein?
LRP chaperone MESD, LDLR chaperone MESD, Mesoderm development candidate 2, Mesoderm development protein.
What is the protein family that this protein belongs to?
Belongs to the MESD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Note=Released from apoptotic cells and shed photoreceptor outer segments.
Protein: ARGE_SALPB
Sequence: MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTALRPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLRC_ASPNG
Sequence: MVRQLILISSLLAAVAVRAPADPAHPMVTEAPDVNLVEKRATTCTFSGSEGASKASKSKTSCSTIYLSDVAVPSGTTLDLSDLNDGTHVIFQGETTFGYEEWEGPLVRVSGTDITVEGESDAVLNGDGSRWWDGEGGNGGKTKPKFFYAHDLTSSTIKSIYIENSPVQVFSIDGSTDLTMTDITVDNTDGDTDDLAANTDGFDIGESTYITITGAEIYNQDDCVAINSGENIYFSASVCSGGHGLSIGSVGGRDDNTVKNVTFYDVNVLKSQQAIRIKTIYGDTGSVSEVTYHEIAFSDATDYGIVIEQNYDDTSKTPTTGVPITDFVLENIVGTCEDDDCTEVYIACGDGSCSDWTWTGVSVTGGSVSDDCLNVPSGISCDL
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase C, PGC, Pectinase 3, Pectinase C, Polygalacturonase C, Polygalacturonase III, PG-III.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VNPA_PSEPO
Sequence: SGSKTANIGDGCFGVPIDHIGSTSGMGCGSPRPKPTPGGS
What is the function of this protein?
Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity).
What are the official names of this protein?
Natriuretic peptide PpNP-a.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASTB_ACIB3
Sequence: MKGYEVNFDGLVGPTHHYAGLSFGNEASTKNRNNLSNPKLAAKQGLLKMKALADMGMKQGVLAPHERPHVPMLRRLGFTGDDISVVAQAMRYSPELLSSLSSASPMWTANAATVSPSADSQDERVHFTAANLNNKFHRSIEAETTSQVLQAIFKNERHFVHHEALPQVALFGDEGAANHNRLGGDYAKRGVQVFVYGQQHLNNGLPGPKRYPARQTREASEAIARLHRLDEAHTVFVQQNPDVIDQGVFHNDVIAVSNQQVLFHHQHAFLNQDQAFAEIRQKMASIGEDFISIEVPENRVTVDDAVATYLFNSQILTRPDGGMTIVVPEESRQNAAVWSYLNDMIQMGTPIDAIQVYDLRESMRNGGGPACLRLRVALNETELNAVNPKVLMNDQLFMTLNQWVDKHYRDRLAQEDLADPHLLMESRMALDELTKILGLGSVYPFQK
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: AQPZ1_AGRFC
Sequence: MSRKFISEFLGTFWLVFGGCGSAVFAAAFPELGIGFLGVAFAFGLTVLTMAYAVGGISGGHFNPAVSVGLTVAGKFPAANLVPYIVAQVLGAVVAAAALYVILTGKAGAEIGGFAANGYGEHSPGGYSLLSALLIEIILTAFFLVVILGSTHGRVPVGFAPVAIGLALTLIHLISIPVTNTSVNPARSTGQALFVGGWALQQLWLFWLAPILGGAIGAVVWKIFGEEEKAGHAGSVQPAKT
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
What are the official names of this protein?
Aquaporin Z 1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SDC4_CHICK
Sequence: MPLPRAAFLLGLLLAAAAAESVRETETMDARWLDNVGSGDLPDDEDIGEFTPHLTSDEFDIDDTSGSGDYSDYDDAIYLTTVDTPAISDNYIPGDTERKMEGEKKNTMLDNEIIPDKASPVEANLSNKISMASTANSSIFERTEVLTALIAGGAVGLLFAVFLILLLVYRMKKKDEGSYDLGKKPIYKKAPTNEFYA
What is the function of this protein?
Cell surface proteoglycan which regulates exosome biogenesis in concert with SDCBP and PDCD6IP.
What are the official names of this protein?
Syndecan-4.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: EIF3A_DROWI
Sequence: MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCETLYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAILLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCQRIQSVVDTIESGPAETSLLTPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELASFCNVFELEKLLVESVRHNDMQIRIDHQKHCIYFGTDLTESQREYRPDGPTLQSMPSEQIRSQLVNMSTVLTRAVSIVYPDREREQRAKLRTQMVHHYHEIKDREHQRILQRQKIIEDRKEFIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRENEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLTEKQVKDKEFWEATEQTRIENAITERKDAVSQQERLKRMYPDRDEYLEALKKERASLYLEKVEKFEIALEVERKKRLADRVIRRREERRQAHLREKEEERLRKEEEIRMAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLAREVAVERERSDKERDTWRPRGDRPEGRPSAAAGGGGASEWRRPAPTADRADRDRGADRDRGADRDRGADRDRGADRERGADRDRKDNEAGGASDSWRVRREPDSQRNAAPKDGGGSSGGAQPSRDDKWRRGGDRERDRDFRNDGQGPRRGGDREDDRDRGGFRRNDGPRRNEEQQRETGGNWRDAPRQSDNRDNRRPAGGDRRDRDRDVRGAGPKEGGGGGGGNWRTAPAPRDEKPTTKQRDQPQDKENKAGDDGEWTSVKRR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_PSEPK
Sequence: MSRKYFGTDGIRGRVGEYPITPDFMLKLGWAAGMAFRKQGHCRVLVGKDTRISGYMFESALEAGLSAAGADVMLLGPMPTPAIAYLTRTFHAEAGIVISASHNPHDDNGIKFFSGQGTKLPDEVELMIEELLDQPMTVVESGKLGKVSRINDAAGRYIEFCKSSVPSSTSFEGLKLVVDCAHGATYKVAPSVFRELGADVTVLHAQPDGLNINEGCGSTHIESLQAAVLVGHADLGIAFDGDGDRVLMVDHTGAIVDGDELLFIIARDLQEHGKLQGGVVGTLMSNLGLELALKDLDIPFVRAKVGDRYVMAELLEREWLVGGENSGHVVCCNHTTTGDAIIAALQVLMALKRRGETLAQARQALRKCPQVLINVRFGASKVDPLEHPAVKEASAKVTEALAGRGRVLLRKSGTEPLVRVMVEGEDESQVRAHAEALAKLVGEVCV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RS7_MYCA9
Sequence: MPRKGPAPSRPLVNDPVYGSQLVTQLVNKVLLDGKKSIAERIVYGALEQARDKTGTDPVVTLKRAMDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWLVTFSRARREKTMVERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CAPP_PSYIN
Sequence: MTEEYSNLRSNVSLLGQLLGKSIGGHLGEEFLDKIETIRQLSKSSRAGNQQDGVALIDMLTHLSDDELVPVARAFTHFLNLANIAEQFHGISRHCDSGVCAPEPIKDLISKFKNSNLSQQEMQQSVNELKMEMVLTAHPTEITRRTLIHKHIAINDCLSYLEISDISDKERDLLLNRLEQLITQAWHTNDIRQKRPTPVDEAKWGFATIEKSLWQAVPQFIRDLESELQSGLGLSLPLEASPITFTSWMGGDRDGNPFVTAKVTQEVLLSSRWVAVSLYLKDISQLTDELSMDNCDPALRSVVGDNAAEPYRAILRKLRSELKETLASLSATLQNQRSDEKDIITTSKQLKEPLLLCYHSLKNMGMNSIANGLILDILRRLNCFGINLLKLDIRQDAERHGNTLSELTRYLGIGDYNAWNEEDKQAFLLQELNNKRPLFPSQWNPSAEVQEVLDTCKVVAQTDPEALGIYIISMARQASDVLAVQLILKEVGCPFRIPVAPLFETLDDLNNSAAVMKRLFAIDWYRGYINGIQHVMIGYSDSAKDAGVIAANWAQYTSQEALVKLSAENDINLVLFHGRGGTIGRGGAPARQALLSQPPGSLKGGLRVTEQGEMIRFKFGLPKVAVQSLNQYAAAVLEANLLPPPAPKQEWRDVMQQFSDQSCQEYRHFVREEPDFVPYFRSVTPEVELGKLALGSRPSKRKPSGGIESLRAIPWIFAWSQNRLMLPAWLGAGTSLKTLLNEGKKPLLQEMYQHWPFFHTRLEMFEMVFLKADEELTKFYEERLVPKELWPLGQRLRDNLTLTRETVLETIPDHQLMQEQPWIKESISLRNPYVDPLNMLQAELLYRSRENGDEICPVVDQALMVTIAGIAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: GET3_ASHGO
Sequence: MTDITPEASLRSLINSTTHKWIFVGGKGGVGKTTSSCSIAIQMALAQPTKQFLLISTDPAHNLSDAFNEKFGKDARKVTGMDNLSCMEIDPSAALKDVNDMAIANGGDDDGLSGLLQGGALADLTGSIPGIDEALSFMEVMKHIKKQEQGDGEHFDTVIFDTAPTGHTLRFLQLPTTLTKVLDKFGAIAGRLGPMLNSFAGNPNVDVLGKMNELKESVQKIKKQFTDPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAESDKEHNCKRCQARWKMQKKYLSQIDELYEDFHIVKMPLCAGEIRGLENLKKFSCFLNNKYDPETDGELVYQLEQGL
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting.  Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.  Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Golgi apparatus. Note=GET1 and GET2 are required for targeting GET3 to the endoplasmic reticulum.
Protein: RSMH_BRUA1
Sequence: MASLGGDNSQAEGAEVRHVPVLIAEVIDALKPAPGAVIVDGTFGAGGYTRRILETGADVIAIDRDPTAIEAGRAMEKEFPGRLNLVESRFSALDEAVARMSGAGKKVDGVVLDIGVSSMQIDEAERGFSFQKDGPLDMRMSSRGPSAADAVNRLKTGDLARIFNFLGEERHAGRIARMIEKRRAAKPFTRTLDLANAIETLVGRNPKDRIHPATRVFQALRVYVNDELGELARALLAAERILKPGGRLVVVTFHSLEDRMVKRFFADRAGGSAGSRHMPETHMRLPSFTPAVKGAVGPTPEEEERNPRARSAKLRAGIRTENPPLEDDLSLFGLPKLPETNELARS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_HELAH
Sequence: MAIYLDFENHIKEIQNEIELALIRGDEDAKEILEKRLDKEVKTIYSNLTDFQKLQLARHPDRPYAMDYIDLILKDKYEVFGDRHYNDDKAIVCFIGKIDNIPVVVIGEEKGRGTKNKLLRNFGMPNPCGYRKALKMAKFAEKFNLPILMLVDTAGAYPGIGAEERGQSEAIAKNLQEFASLKVPTISIIIGEGGSGGALAIAVADKLAMMEYSIFSVISPEGCAAILWDDPSKTEVAIKAMKITPRDLKEAGLIDDIILEPSKGAHRNKISAANTIKEYFLDTLRTIQQDPHFLDNRYKKLMSLGSFVESMPH
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_SBWMN
Sequence: MPIDSSSILGIISEEDVIRAAISTSATKFGSQLHSTVCDHVKETYLDAVERQKVKKKIDVRRDLSQEQLQLLNDLYPERHIVSSNCERGTHSFAAASRKIETDLLLSRIPKRSWVYDIGGNWATHVKRNDGRKVHCCCPTVDIRDSARKTVRWASIEKYLDEKEEIPPEIGERIKRLQADEDRIYANLKSEKAQPEDLDGKWYCGNRFEDCVFRADRAYAMAIHSIYDIDLSDLANALEEKRIKVMSGTFLFSVDLLLGKKSGTLPTMDGFFEVEDGYVKYGFHNDTNPGYKHNLNQLMKYLTKTFVVAKGGTIYYLELTEQRGDVMFFTMTDATEARMNGVVADESFKCIPIDNKDEVVFPIFEVDQKTDALVFSEILLSRDFVQRAIEYTGRLKPAQLTSDNVNTYLTSTNNTIIIGGSSKKNATKVDATLIQQITTTLIVWTELMNQRQKRVLEKLRMQMKDDVDFMTLAHATFLKMFGKVSYYQRALRCFANWISYVHGADAIQFRNVPLYAEVTDRIKLWKNYAPNQGFVLDLEELDVKIKLHEITEREKRDVSRCIVSGKLGELSSVDNTECGAVLDGKDYKDSRRKTTFEDLLDGEVATNFLDNWCDKTDHFNFSRSDAVSKYAWGMKLLKGVWEFLLPPLHFAPVYVDAEQARIRLNAEIVTVVEHAVTESNVGLTGVEKAEFADAMSFLVGAAKHLEKRKEVAQQAVVEAVEAVRELRKVHSPADVCNAVDLWSAFEKDLDDDDETGTTATIVEKGKAVCDDDVQVVLCGSSSTSSVEEVSKEAELFVETIESQASSVTETSDVTTEVAASSSDESVMSEVPEKSWASVAEDESDDSYYLRSMIISDKVQKSALPKRPDFSKYSTLQQKAKQEALWYLQCKIVSDRTTLRSIIDDHLRGMFHNGNCELPKDSAFLDYTVDNCGTWMYGKPSRPGHSYGVGFSLDTKQRITKCELVKLMWNRDCRGQMNQKPVNTRAFQYLLLSDLSFMMNELVIYRNLQQVVKKKERTKQARITLRDGVPGCGKSTWILNNANPMKDMVLCVGKEATEDLKEKFMKKHKCAESDLKRIRTVDSFLMHDYDKFRAATVHFDEALMAHAGIVYFCADILGAKKVICQGDSQQIPFINRVESITLQYAKLAIDETEYVRLTYRSPVDVAHYLTKKSWYSGGRVTTKNSVLRSMKVVGPRDAKPMTSVHCVPYHRDAQYLTFTQSEKADLYKALRAKGPVEVNTVHETQGKTFDDVIVVRLKTTENEIYPGGRKGQPYEIVATTRHRRSLVYYTAIEDRLFEDISDMQDVMESKLMKNLCSELTKXRFGSKYESILICDREVRVPDVGTPVIIQDFYDRVLPGNSTMDSHFDGYEVSTSDISIELENCTVQPNKNVKVWQDKRGLVPVLRTAMPPKRQNLPVEAMLALKKRNMAAPKLQEAVNEFEVIERTVNRAKEIFFDTSLIDDSEVSTRESNLRWWKRQSTTAKAQLKKETRLLHELDLCYYNYCIKGDEKPKMDRSPQHEYGALQTVVFPDKIVNALFGPAMKEINERIRLALKPHVVYNSRMNAEELNRTVEFLDPEEDFNAFEIDFSKFDKSKTSLHIRAVIELYKLFGLNDLFALLWEKSQCQTKIRDFVNGITAYLLYQQKSGNCDTYGSNTWSAALALLESMPLEKAKFMIFGGDDSLILFPKHLTIEDPCRRLASLWNFDCKLFDFKHNMFCGKFLLKVGDRFKFAPDPMKLITKLGRKDIVDGRLLSEIFVSVGDNYRSYRDYRILEQLTYALRERYRTTEDPTAALVALKKYIFDFKLWASMFNYKGEFVECRVDRNFEW
What is the function of this protein?
Is a methyltransferase active in RNA capping and an RNA helicase.  Methyltransferase displays a cytoplasmic capping enzyme activity.  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus.  Helicase region probably exhibits NTPase and RNA unwinding activities (Potential).
What are the official names of this protein?
Replicase large subunit, 209 kDa readthrough protein, RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: GLPK_ECO7I
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISADQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y526_METVS
Sequence: MKEVGIVGYGSDLPKYRIKAEEIAKAWGKDAEAIKKGLVVNEKSVPGPDEDSATIAVQAARRALSRSGINPKNIGAVYVGSESHPYAVKPTSGIVAEAVCTSPEVTAADLEFACKAGTAGIQMCMGLVSSGMMDYAMAVGVDTAQGAPGDALEYTAAAGGAAYIIGGKKEELIAKFNGTYSYTTDTPDFWRREHEHYPKHGGRFTGEPAYFRHVLSAAKGMMEKMDTTTKDYDYCVFHQPNGKFYLSAAKQLGFNENQYRYGLLTPYLGNTYSGAVPLGLSNILDHSKTGDRIFVVSYGSGAGSDAFDITVTDRISEVINKAVTTEELLSRKKYIDYAVYLKYRGKIRM
What are the official names of this protein?
UPF0219 protein Mevan_0526.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. UPF0219 family.
Protein: Y3085_CERSK
Sequence: MQEYRLVLVTGPSGAGRTTAINALEDMGYEVIDNLPLSFVPRLIEGPSIGRPIALGLDVRNRDFNATALIELIDRLTQDPRVALEVLYVDCSASELIRRYNQTRRRHPLAPAETPAEGVEREIDLLAPVRVRADHLIDTSEMSPHDLKAELSRWFDRGAATRLAVSVQSFSYKRGVPRGVDMIFDCRFLKNPYWVESLRALDGREASVADYISSDPRFAPFFEKLRDLVLFLLPAQLEEGKAHLSLGFGCTGGQHRSVAVAELLGNALAEAGWPVSKRHRELERRAAAVLPTHQGEKA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein RSKD131_3085.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RSGA_PROM3
Sequence: MAAAEAPRLAGMVVALQANFLEVELETFNPSSLVSWRRSTDAEPLRLLCTRRTRLDHRGAAVHVGDRVWVEAIDWQERRAVVGDVEPRQSWINRPPVANVTAVVVALAVKQPCFDADQASRFLLSAEQTGVDVHLILTKRDLITSDQLEQQLVRLRGWGYRPMAVSVQTGEGLGALKNKLSSTRLAVFCGPSGVGKTSLLNQLLPQLSLRVGAVSGRLQRGRHTTRHVELFRLCEGSLVADTPGFNRPELPADPRKLAVLFPEFDGQIEDYPCRFRDCFHRDEPGCGVDKSWERYPIYKRFLEEMECLSRSSRGGSGSGLL
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3E_XENTR
Sequence: MAEYDLTTKIAHFLDRHLVFPLLEFLSVKEIYNEKELFQGKLDLLSDTNMVDFAMDVYKNLYADKEIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDHLAEKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPSTDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNTVSSPLQSLQHRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISISMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLAFRSQMLAMNIEKKTNQNSRTEAPTWAAQDSGFY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e, Eukaryotic translation initiation factor 3 subunit 6.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SLEB_BOTJA
Sequence: DCPPDWSSYEGHCYRFFKEWMHWDDAEEFCTEQQTGAHLVSFQSKEEADFVRSLTSEMLKGDVVWIGLSDVWNKCRFEWTDGMEFDYDDYYLIAEYECVASKPTNNKWWIIPCTRFKNFVCEFQA
What is the function of this protein?
Snaclec that binds to von Willebrand factor (VWF) and induces its interaction with GPIbalpha (GP1BA) (via the vWF A1 domain), resulting in platelet aggregation.
What are the official names of this protein?
Snaclec botrocetin subunit beta, Platelet coagglutinin.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPA_SHEON
Sequence: MNSISNQTIPHQASRYQAAFSRLKAEGRGAFVPFVTLGDPSPELSLKIIDTLVQNGADALELGFPFSDPLADGPVIQGANLRALAAGTTPTACFELLAKIRAKYPELPIGLLLYANLVFANGIDAFYAKAQQAGVDSVLIADVPVEEAAPFIQAAKAHGIAPIFIAPPNADSDTLAKVSQSGEGYTYLLSRAGVTGADTKAGTPVEEILAKLQEFNAPPPLLGFGIAEPAQVSAAIKAGAAGAISGSAVVKIIETHQQDEVKLLAALGEFTRTMKAAT
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: YH071_YEAST
Sequence: MVGRLRLAEGLNIPSFLGLAHQFSVSKDVDLSLVDRLCQNKILSSVLYFLCGRRLLVRLLGTAVHYWRGLCSMALLKAEGMYYIFFFLRKCISVNNRYKNFSPKRL
What are the official names of this protein?
Putative uncharacterized protein YHR071C-A.