PharMolix/UniProtQA huggingface dataset:
Protein: RIMP_PSEPK
Sequence: MHEGVQVSSKLEQLQALLAPVVEGLGYQCWGIEYVSQGKHSVLRIYIDKEGGILVDDCEAVSRQASAILDVEDPISSEYTLEVSSPGMDRPLFTLEQFASHAGEQVKIKLRSPFEGRRNFQGLLRGVEEQDVVVQVDNQEFLLPIDSIDKANIIPSFD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_LACAC
Sequence: MDNRPIGLLDSGFGGLSVAKKVIEKLPNESTIFIGDNAHIPYGDRTREDIINLTRRSVKFLLEKNVKLIVIACNTATAVAMPTMQKEVEQQIIGVIQSGALAAARTTKNKNVAVVATNVTVASHAYQKEIKFRDPEIKVTELAAPKLAPLVEAQKDYATNLKVVKESLAPLMGKEFDTLVLGCTHYPLIQKEFEEAINNKEVTILDPADQVAQYTFNVMRRDGLFSDSEKAVHEYYTTGNSETFDKLARTFMDDDTLTSKHVDTENY
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: Y4155_YERPY
Sequence: MDEWYGQVAPREKLLKYGAAVLTDAELLAIFLRTGIPGMHVMKMAEYLIETFGSLHGLISADYQTLCAHKGIGASKYSQIQAIGELACRCFSSHLMRESVLLNPGITQKFLQNILSHREREIFLVVFLDNQHRVIRHEEMFTGTISSVEVHPREIVREALKVNAAALILAHNHPSGKAEPSQADRLITTQVIKACSLLDIRVLDHLVVGRGECVSFAERGWL
What are the official names of this protein?
UPF0758 protein YPK_4155.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: ORTH5_ARATH
Sequence: MAIQTQLPCDGDGVCMRCQVNPPSEETLTCGTCVTPWHVSCLLPESLASSTGDWECPDCSGVVVPSAAPGTGISGPESSGSVLVTAIRAIQADVTLTEAEKAKKRQRLMSGGGDDGVDDEEKKKLEIFCSICIQLPERPVTTPCGHNFCLKCFEKWAVGQGKLTCMICRSKIPRHVAKNPRINLALVSAIRLANVTKCSGEATAAKVHHIIRNQDRPDKAFTTERAVKTGKANAASGKFFVTIPRDHFGPIPAANDVTRNQGVLVGESWEDRQECRQWGVHFPHVAGIAGQAAVGAQSVALSGGYDDDEDHGEWFLYTGSGGRDLSGNKRVNKIQSSDQAFKNMNEALRLSCKMGYPVRVVRSWKEKRSAYAPAEGVRYDGVYRIEKCWSNVGVQGLHKMCRYLFVRCDNEPAPWTSDEHGDRPRPLPDVPELENATDLFVRKESPSWGFDEAEGRWKWMKSPPVSRMALDTEERKKNKRAKKGNNAMKARLLKEFSCQICRKVLSLPVTTPCAHNFCKACLEAKFAGITQLRDRSNGVRKLRAKKNIMTCPCCTTDLSEFLQNPQVNREMMEIIENFKKSEEEAEVAESSNISEEEGEEESEPPTKKIKMDKNSVGGTSLSA
What is the function of this protein?
E3 ubiquitin-protein ligase.  Participates in CpG methylation-dependent transcriptional regulation and epigenetic transcriptional silencing.  Mediates ubiquitination with the E2 ubiquitin-conjugating enzyme UBC11.
What are the official names of this protein?
E3 ubiquitin-protein ligase ORTHRUS 5, Protein VARIANT IN METHYLATION 2, RING-type E3 ubiquitin transferase ORTHRUS 5.
What are the subcellular locations of this protein?
Nucleus. Note=Broadly distributed in the nucleus and enriched in the heterochromatic chromocenters.
Protein: SURE_GEOMG
Sequence: MKILVTNDDGVRAPGIRSLAEALRNIGDVVVVAPDRERSAVGHALTLHHPLRASEIRPAVFAVDGTPTDCVNLGIHTLLGSRPDIVVSGVNCGGNMGDDITYSGTVSAAMEATLMGIPALAVSLATSGRGDNYAVASAFAARLVRIVSERGLPPDTLLNVNVPDLPLEKLGGAVVTIQGKRDYEGKIVTKTDPRGRNYYWIGNGSLQFRDLEGTDYYAVKRGLVSITPLHLDLTNYASLTTLKTWDFAEMTL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_STAAN
Sequence: MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAIDEADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVSHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVNDVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RIMO_CLONN
Sequence: MNRYKIGLISLGCDKNRIDSELLLGKLNEKNDIVNDPNKADIIIVNTCGFIESSKQESIDTILEMAKYKEENCKMIIATGCLTQRYSKELLELIPEIDIMLGVNDYANIQNYIDDFFNEHNKICQCKYSDISINEGKRILTTAKHMAYIRISEGCNNLCTYCIIPKIRGKYRSRSIESIINEAKELANMGVKELILVGQDTAIYGSDLYKENRLSQLLRELSNIEDIEWIRILYTYPEEITDELIEEIKNNDKVCKYLDIPIQHISNTVLKRMNRKSSKELITDNIKKMRKEIDGLCLRTSIIVGFPGETEDEFNELKEFVEEIKFDNLGVFKYSQEEDTAAARMKDQVSEDLKEERLATIMSIQQNVSSKINKNKLEKVYKVLVEGQNDKYYIGRNYQMVPEIDGAIFFKCDKILNVGEFVYVKITDTLEYDLIGVVCDESGQ
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUG_ENT38
Sequence: MINDILAPGLRVVFCGINPGKSSAHTGFHFAHPGNRFWKVIHQAGFTDKLLKPEEEQHLLDTRCGITMLVERPTVQANEVNLHELRSGGRELVKKIEDYQPAALAILGKQAYEQAFSQRGAQWGKQRITIGMTQVWVLPNPSGLNRATLDKLVEAYRELDEALVVRGR
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_BACLD
Sequence: MPKVALYNQNGSTAGDIELNDSVFGIEPNESVVFDAILMQRASLRQGTHKVKNRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGIVFGPTPRSYAYKLPKKVRRLAIKSALSSKVNDNNLIVLEDLNLDAVKTKEMAAILKGLSIEKKALIVTADANETVELSARNLPGVTVVEANGINVLDVVGHEKLVMTKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NGN2_MOUSE
Sequence: MFVKSETLELKEEEEVLMLLGSASPASATLTPMSSSADEEEDEELRRPGSARGQRGAEAEQGVQGSPASGAGGCRPGRLLGLMHECKRRPSRSRAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCAGAGGLQGALFTEAVLLSPGAALGASGDSPSPPSSWSCTNSPASSSNSTSPYSCTLSPASPGSDVDYWQPPPPEKHRYAPHLPLARDCI
What is the function of this protein?
Transcriptional regulator.  Involved in neuronal differentiation.  Activates transcription by binding to the E box (5'-CANNTG-3').
What are the official names of this protein?
Neurogenin-2, NGN-2, Helix-loop-helix protein mATH-4A, mATH4A, Protein atonal homolog 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: HISZ_CUPTR
Sequence: MSNHWLLPENIADVLPSEARKIEELRRRMLDLFRTYGYELVMPPMLEYLESLLTGTGHDLDLRTLKLVDQLSGRTMGLRADITPQVARIDAHLLNRPGVTRLCYAGNVLHARPAGFHATREPIQIGAEIYGHAGLEADVEIQELMLAALTAAGLSDIRIDLCHAGILEALLAGLPSIRKIEDALFAALETKDVPALRELTAGMPQTERDALLALPTLYGGVEVIERARATLPASPAIGRALDELAALAVQVRGASVNIDLSDLRGYHYHSGVMFAAYVAGLPNYVARGGRYDKVGEAFGRARPATGFSLDLREVAALSPVEVRALAIFAPWDADPALRAAIAGLRAGGEIVIQSLPGHTHELDEFNCDRQLVRKDAGWVVVPR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C93C1_SOYBN
Sequence: MLLELALGLLVLALFLHLRPTPTAKSKALRHLPNPPSPKPRLPFIGHLHLLKDKLLHYALIDLSKKHGPLFSLYFGSMPTVVASTPELFKLFLQTHEATSFNTRFQTSAIRRLTYDSSVAMVPFGPYWKFVRKLIMNDLLNATTVNKLRPLRTQQIRKFLRVMAQGAEAQKPLDLTEELLKWTNSTISMMMLGEAEEIRDIAREVLKIFGEYSLTDFIWPLKHLKVGKYEKRIDDILNKFDPVVERVIKKRREIVRRRKNGEVVEGEVSGVFLDTLLEFAEDETMEIKITKDHIKGLVVDFFSAGTDSTAVATEWALAELINNPKVLEKAREEVYSVVGKDRLVDEVDTQNLPYIRAIVKETFRMHPPLPVVKRKCTEECEINGYVIPEGALILFNVWQVGRDPKYWDRPSEFRPERFLETGAEGEAGPLDLRGQHFQLLPFGSGRRMCPGVNLATSGMATLLASLIQCFDLQVLGPQGQILKGGDAKVSMEERAGLTVPRAHSLVCVPLARIGVASKLLS
What is the function of this protein?
Involved in isoflavonoid biosynthesis.  Converts liquiritigenin to 2-hydroxyisoflavanone which spontaneously dehydrates to daidzein.
What are the official names of this protein?
2-hydroxyisoflavanone synthase, Cytochrome P450 93C1v2, Isoflavone synthase 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: ADAM8_HUMAN
Sequence: MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP
What is the function of this protein?
Possible involvement in extravasation of leukocytes.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 8, ADAM 8, Cell surface antigen MS2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: U74G1_STERE
Sequence: MAEQQKIKKSPHVLLIPFPLQGHINPFIQFGKRLISKGVKTTLVTTIHTLNSTLNHSNTTTTSIEIQAISDGCDEGGFMSAGESYLETFKQVGSKSLADLIKKLQSEGTTIDAIIYDSMTEWVLDVAIEFGIDGGSFFTQACVVNSLYYHVHKGLISLPLGETVSVPGFPVLQRWETPLILQNHEQIQSPWSQMLFGQFANIDQARWVFTNSFYKLEEEVIEWTRKIWNLKVIGPTLPSMYLDKRLDDDKDNGFNLYKANHHECMNWLDDKPKESVVYVAFGSLVKHGPEQVEEITRALIDSDVNFLWVIKHKEEGKLPENLSEVIKTGKGLIVAWCKQLDVLAHESVGCFVTHCGFNSTLEAISLGVPVVAMPQFSDQTTNAKLLDEILGVGVRVKADENGIVRRGNLASCIKMIMEEERGVIIRKNAVKWKDLAKVAVHEGGSSDNDIVEFVSELIKA
What is the function of this protein?
Involved in the biosynthesis of steviol glycosides in leaves (PubMed:15610349).  Converts steviol to the mono-glycoside steviolmonoside (PubMed:15610349).  Converts the mono-glycoside steviolmonoside to the bi-glycoside rubusoside (PubMed:15610349).  Converts the bi-glycoside steviolbioside to the tri-glycoside stevioside (PubMed:15610349).  Converts the tri-glycoside rebaudioside B to the tetra-glycoside rebaudioside A (PubMed:15610349).
What are the official names of this protein?
UDP-glycosyltransferase 74G1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: TDCC_SALDC
Sequence: MSTTDSIVSSQAKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLQMPALNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLSNIALTGHDGILVTVWLGISIMVFSFNFSPIVSSFVVSKREEYEKEFGREFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPQNMADAKAQNIPVLSYLANHFASLSGTKSTFATVLEYGASIIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKTKVSMGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTLIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPP11_PORG3
Sequence: MKKRLLLPLFAALCLSQIAHADEGMWLMQQLGRKYAQMKERGLKMKEYDLYNPNGTSLKDAVVLFDGGCTGEVVSDRGLVLTNHHCGYDMIQAHSTLEHNYLENGFWAMREADELPNKDISVVFIDKIEDVTDYVKKELKAIKDPNSMDYLSPKYLQKLADKKAGKNFSAKNPGLSVEIKAFYGGNLYLMFTKKTYTDVRLVGAPPSSIGKFGADTDNWIWPRHTGDFSIFRIYADKNGNPAPYSEDNVPLKPKRFFNISLGGVQENDYAMIMGFPGTTHRYFTASEVDEWKSIDNDIRIRMRDIRQGVMLREMLADPQIKIMYSAKYAASQNAYKRAIGANWAIKTRGLRQNKQAMQDRLIAWGAKQGTPRYEEAVHEIDATVAKRADLRRRYWMIEEGIIRGIEFARSPIPTEDETKALQGNDASARKEAIDKIRTRYSKFANKDYSAEVDKKVAVAMLTEYLKEIPYENLPLHLRLVKDRFAGDVQAYVDDIFARSVFGSEAQFDAFAAVPSVEKLAEDPMVLFASSVFDEYRKLYNELRPYDDPILRAQRTYIAGLLEMDGDQDQFPDANLTLRFTYGQVKGYSPRDNVYYGHQTTLDGVMEKEDPDNWEFVVDPKLKAVYERKDFGRYADRSGRMPVAFCATTHTTGGNSGSPVMNANGELIGLNFDRNWEGVGGDIQYLADYQRSIIVDIRYVLLVIDKVGGCQRLLDEMNIVP
What is the function of this protein?
Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.  Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has a hydrophobic residue preference at the P2 position.  Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA.  Is involved in amino acid metabolism and bacterial growth of asaccharolytic P. gingivalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.
What are the official names of this protein?
Asp/Glu-specific dipeptidyl-peptidase, Dipeptidyl-peptidase 11, DPP11.
What is the protein family that this protein belongs to?
Belongs to the peptidase S46 family.
What are the subcellular locations of this protein?
Cell surface. Note=Is exclusively cell-associated.
Protein: INTD_ECOLI
Sequence: MSLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVEKLGDLPDVTFEEACLRWLEEKADKKSLDSDKSRIEFWLEHFEGIRLKDISEAKIYSAVSRMHNRKTKEIWKQKVQAAIRKGKELPVYEPKPVSTQTKAKHLAMIKAILRAAERDWKWLEKAPVIKIPAVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSNIINLEWQQIDMQRRVAWVNPEESKSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKAAKRADGTSTPAVRKMRIDSKTSWLSACRRAGIEDFRFHDLRHTWASWLIQSGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARKIDDIFGDNVPNMSHSEIMEDIKKA
What is the function of this protein?
Integrase from the cryptic lambdoid prophage DLP12.  Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
What are the official names of this protein?
Prophage integrase IntD, Prophage DLP12 integrase, Prophage QSR' integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: DAPB_PSEAJ
Sequence: MRRIAVVGAAGRMGKTLIEAVQQAPGAGLTAAIDRPDSTLVGADAGELAALGRIGVPLSGDLAKVADEFDVLIDFTHPSVTLKNLAFCRKAGKAMIIGTTGFSAEEKQRLVEAGKDIPIVFAANFSIGVNLCLKLLDTAARVLGDEVDIEITEAHHRHKVDAPSGTALRMGEVVASALGRDLEKVAVYGREGQTGARDRQTIGFATIRAGDVVGDHTVLFAADGERVEITHKASSRMTFAKGAVRAAMWLDGKAPGLYDMQDVLGLH
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_PSEA8
Sequence: MKASLLKKLDVLSDRYEELTALLGDAEVISDQTRFRAYSREYAEVEPVILAFRDYRKVQADLEGAQALLKDSDPELRDLAEEEVAEARGRLAALGDSLQRMLLPKDPNDSRNVFLEIRAGTGGDEAAIFSGDLFRMYSRYAERQGWRVETLSENEGEHGGYKEVIARVEGDNVYAKLKFESGAHRVQRVPETESQGRIHTSACTVAVLPEPDEQAAIEINPADLRVDTYRSSGAGGQHVNKTDSAVRITHIPSGIVVECQEERSQHKNRAKAMAWLAAKLNDQQQAAAQQAIASTRKLLVGSGDRSERIRTYNFPQGRVTDHRINLTLYSLGEVMEGAVEQVIEPLLQEYQADQLAALGD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAS_STAAR
Sequence: MNNLKWVVYFLKSRKNWIFWILFLNILMLGISLIDYDFPIDSLFYIVSLNLSLTLIFLILTFFKEVKLYRHFEKDKEIEEIKHKDLAETPFQRHTVDYLYRQILAHKDKVVDQQLQLNMHEQTITEFVHDIKTPVTAMKLLIDQEENQERKQALLFEWSRINSMLDTQLYITRLESQRKDMFFDYVSLKRMVIDEIQLTRHISQVKGIGFDIDFKVDNHVYTDIKWCRMIIRQILSNALKYSENYNVDISTELIDQHVALIIKDHGRGISKKDMPRIFERGFTSTANRNETTSSGMGLYLVDSVKDQLGIQLQVTSTIGKGTTVKLIFPLQNEIVERMSEVTNLSF
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Functions as a sensor protein kinase which phosphorylates GraR through the auxiliary protein GraX.  In turn, GraR up-regulates many genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Sensor protein kinase GraS, Glycopeptide resistance-associated protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL9_ECO8A
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SYI_PECCP
Sequence: MSDYKTTLNLPETGFPMRGDLAKREPDMLKRWYEQDLYGIIRNAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQLIGKPGEKVSAAEFRAECRKYAAEQVAGQKADFIRLGVLGDWDRPYLTMDFKTEANIIRALGRIIENGHLHKGAKPVHWCADCGSALAEAEVEYYDKTSPSIDVAFNASDVAAVLAKFGVSSVDGPVSLVIWTTTPWTLPANRAISLNAEFDYQLVQIDGQALILAADLVESVMKRAGVTQWTVLGDCKGADLELLRFKHPFLSFDVPAILGDHVTLDAGTGAVHTAGGHGPDDYVISQKYNLEIANPVGPNGCYLSGTYPELDGKFVFKANDLIVEILREKGMLLHVEKLQHSYPCCWRHKSPIIFRATPQWFVSMDQKGLRKQSLSEIKGVQWIPDWGQARIEAMVANRPDWCISRQRTWGVPMSLFVHKETEELHPRTAELIEAVAKRVEADGIQAWWDLDPADVLGADADNYVKVPDTLDVWFDSGSTHASVVDVRPEFGGHAADMYLEGSDQHRGWFMSSLMISTAIKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWIGSTDYSGEIAVSDEILKRSADAYRRIRNTARFLLANLNGFDPQKDSVKPEDMVVLDRWAVGCAKAAQEEILEAYESYDFHRVVQRLMQFCSIEMGSFYLDIIKDRQYTAKSDSVARRSCQTALYHISEALVRWMAPIMSFTADEIWSYLPGKRAQYVFTEEWYDGLFGLDASETMNDAFWADILKVRSEVNKVIEQARNDKRIGGSLEASVTLYADANLAGKLNQLRQELHFALLTSKALVERYENAPDSAQATELTGLKIALSEAEGHKCPRCWHYETDIGSNADHPEVCGRCATNVGGNGEERKFV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THY1_DICDI
Sequence: MGLDIQTEIDKIVIEKVKPEVEYYDVMGGSHRWEVKVHDHGKVALVDTMPRLAPVGQTADFSICQAARVSYGAGTKKVTEDKGLIRYLYRHQHTSPFEMVEFKFHCVMPVFIARQWIRHRTANVNEYSARYSVLPDKFYHPSIEEVRKQSTSNRQGGEEALEPKTAQEFLDYLDKVEENYKTYNELLEKGLSRELGRIGLPVSIYTEWYWKIDLHNLFHFLRLRMDSHSQKEIRDYANTIFALIRPIVPVACEAFIDYAFESLKLTRLEIEAIRTGSPLNTTNKREIEEFEEKKKLLFPNTQA
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase thy1, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: NUBP2_DANRE
Sequence: MDGSGKGNLDQVKHVLLVLSGKGGVGKSTITTELALAFRHAGKKVGILDVDLCGPSIPRMLSVGKPEVHQCDSGWVPVYADPQQQQLALMSIAFLLEDSDEAVIWRGPKKTALIGQFVSDVAWGELDILLVDTPPGTSDEHLAVLENLRKHRVDGAVLVTTPQAVSTGDVRREITFCKKTNLKILGIVENMSGFVCPHCSECSNIFSKGGGEELAKLTGSAFLGSVPLDPLLTESLEEGRDFLQAFPESSTFTAISHIANTLLNSLNA
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The nubp1-nubp2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor nubp2, Nucleotide-binding protein 2, NBP 2.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP4_PONAB
Sequence: MASSRASSTATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRASQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
What are the official names of this protein?
U4/U6 small nuclear ribonucleoprotein Prp4, U4/U6 snRNP 60 kDa protein, WD splicing factor Prp4.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: GCST_CUPPJ
Sequence: MTLQATPLNAIHRALGARMVDFGGWDMPVNYGSQIEEHNAVRSDAGMFDVSHMCVVDLNGANTRAFLRGLLANNVDKLQTPGKALYSCMLDEKGGVIDDLIVYFFAEDRFRLVVNASTALGDIEWIRARNDATGSGVTITPRRGDVAPAGALPLAIVAVQGPNARTKVWNTFPSTQPSDALKPFNAVVVHDPAIGEIMVARTGYTGEDGFELVVPAENVAAVWEKLDAAGVRPAGLGARDTLRLEAGMNLYGQDMDINTSPLDAGLAWTVDLQSERDFTGKAALAAAGQRQQFLGLILRDKGGVLRAHQKVVTAAGDGEITSGTFSPSLSQSIAFARLPMGVAVGDTVQVEIRDRKLAATVVKLPFVRNGKALVS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.