PharMolix/UniProtQA huggingface dataset:
Protein: MSB1A_DANRE
Sequence: MSFCSFSGGEIYKDHFESGMYVCAQCGYELFSSRSKYEHSSPWPAFTETIHEDSVSKQEERWGAYKVRCGKCGNGLGHEFVNDGPKHGLSRFUIFSSSLKFIPKVKNEQQ
What is the function of this protein?
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine.  While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue.  Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (mical1, mical2 or mical3) on actin, thereby promoting filament repolymerization.  Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages.
What are the official names of this protein?
Methionine-R-sulfoxide reductase B1-A, MsrB, MsrB1-A, Selenoprotein X-A, SePR, SelX-A.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton.
Protein: TRMB_AZOC5
Sequence: MTALSETEHKGAFYGRRVGKTLRQGQQQALARTLPRYLIDLPTVAEPAALFPCPVDEIRLEIGFGGGEHLLSEAKRFPRAGYIGIEPFLNGMAKAVLELDLAPQENVRLFNLDAALLLARLPEGSVSQVELLYPDPWPKRRHWKRRFVRPDNLDLLARALKPGGVFRFASDVPDYVDWTLREVRAHPAFRWTQTRADDWRTPYEGWPGTRYEAKAIAAGRVPTYLSFARV
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RS10_PSEU2
Sequence: MQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVSPHVNKDARDQYEIRTHKRVLDIVQPTEKTVDALMKLDLAAGVEVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: EAMB_ECOHS
Sequence: MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLAGMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQAKPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCWALAGHLFQRLFRQYGRQLNIVLALLLVYCAVRIFY
What is the function of this protein?
Exporter of O-acetylserine (OAS) and cysteine.
What are the official names of this protein?
Cysteine/O-acetylserine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMHL_STAEQ
Sequence: MEDIVIVGRHAVKEAIISGHAINKILIQDGIKKQQINDILKNAKSQKLIVQTVPKSKLDFLANAPHQGVAALVAPYEYANFDEFLQKQKKKARYSTVIILDGLEDPHNLGSILRTADASGVDAVIIPKRRSVALTQTVAKASTGAIQHVPVIRVTNLSKTIDELKDNGFWIAGTEANNATDYRDLQADMSLGIVIGSEGQGMSRLVSDKCDFHIKIPMVGHVNSLNASVAASLMMYEVYRKRHQLEEKS
What are the official names of this protein?
Putative TrmH family tRNA/rRNA methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: ROB_ECOLI
Sequence: MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMRYQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCELLIPIRR
What is the function of this protein?
Binds to the right arm of the replication origin oriC of the chromosome.  Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication.
What are the official names of this protein?
Right origin-binding protein.
Protein: TATA_BACCN
Sequence: MLSNIGFPGLILILVAILILFGPKKLPEIGRSLGETLKEFKKSTRELTDDAFQEKEKK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y1411_HAEIN
Sequence: MSDVKGKSTSGRGLTPKQEKFCQLYIELGNASEAYRQSYDCSKMTTEVINVKASELLNKNGKITVRVEELRQAHQQRHNLTLDNIIADLQEYRDICMGRKPLTITTVVKNAQEGTAQSVNTECFVFEPTGANKALELLGKHLGMFTNKVDVTTDGKPLPTVINVTFSDEPA
What are the official names of this protein?
Uncharacterized protein HI_1411.
Protein: PRP4B_RAT
Sequence: MAATEPPSLREQPEMDDADNSEKSVNEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDRDKKHKHKHKHKKHKRKEVLDASDKEGLSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTRGKLEITDNKNSAKKRSKSRSKERTRHRSDKRKSKGAVEMMREKANRSKSKERRKSKSPSKRSKSQDQARKSKSPTLRRRSQEKVGKARSPADEKIKSEEKGKIKDRKKSPIVNERSRDRSKKSKSPVDLRDKSKDRRSRSKERKSKRSEIDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKQRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILGRCERSKDASPINRWSPSRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRSRRSRSRLRRRSRSRGGHRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEAVIEQRRIQRQAIVQKYKYLAEDSNISVPSEPSSPQSSTRSRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVEQNNGSSQKKLLAPDMFTESDDMFAAYFDSARLRAAGIGKDFKENPNLRDNWTDAEGYYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKELEFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVRSYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSRFYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMIRKGVFKDQHFDQNLNFMYIEVDKVTEREKVTVMSTINPTKDLLADLIGCQRLPEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI
What is the function of this protein?
Has a role in pre-mRNA splicing.  Phosphorylates SF2/ASF (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PRP4 homolog, PRP4 pre-mRNA-processing factor 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROA_BURPS
Sequence: MDIDQYMTDVGRRARRASREIARASTAAKNAALEAVARAIGRDADALKAANARDVARAKDKGHDAAFVDRLTLSDKALKTMIEGLRQVATLADPIGEMSNLKYRPSGIQVGQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALESNTALAKLIGEGLAAAGLSQDAVQVVGTADRAAVGKLITMTEYVDVIVPRGGKSLIERLINEARVPMIKHLDGICHVYVDDRASVAKALAVCDNAKTHRYGTCNTMETLLVARGIAPAVLTPLGRLYREKGVELRVDADARAVLEAAGVGPLVDATDEDWRTEYLAPVLAIKIVDGIDAAIEHINEYGSHHTDAIVTEDHDRAMRFLREVDSASVMVNASTRFADGFEFGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGHGEGRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_METHO
Sequence: DKKIYALRDVTGTVQSIPLIASSIMSKKLATGSNCILLDVKCGNGAFMKDINEAKKLGKLMIEIGKKLNRKIAVEITNMQQPLGKTIGNKIEVLEAIDTLNGHGPKDFTEIIYSSGSTLLVLAQKAKDEVEARKMIDEVINNKKAYNKFLEWISRQGGNIKVFEKDSKWFNPQYKQEIIASQSGYLKIKSRIDFGLVAMKLGAGRSKKEDSIDYEAGIYLNKSSNEYVNKGDVLFTMYSSKPINPELQKELLSAIEFSESKHDIQTVFAKLM
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: GLUPH_PLAF7
Sequence: MDYENFVKSAEEINNLHNVNYLETKDLNDFNWKAAYYICKEIYDKQQINKDGYVVIGLSGGRTPIDVYKNMCLIKDIKIDKSKLIFFIIDERYKSDDHKFSNYNNIKFLFHNLNINEKEQLYKPDTTKSIVDCILDYNDKIKIMIEKYKKVDIAILGMGSDFHIASLFPNIFYNIYMNNYQNNYIYNEKTLDFINNDQDNDNLKYLKEYVYFTTTNQFDVRKRITVSLNLLANASSKIFLLNSKDKLDLWKNMLIKSYIEVNYNLYPATYLIDTSCTNENVNINNNNNNNNKNKNNYCYSNTTVISCGYENYTKSIEEIYDSKYALSLYSNSLNKEELLTIIIFGCSGDLAKKKIYPALFKLFCNNSLPKDLLIIGFARTVQDFDTFFDKIVIYLKRCLLCYEDWSISKKKDLLNGFKNRCRYFVGNYSSSESFENFNKYLTTIEEEEAKKKYYATCYKMNGSDYNISNNVAEDNISIDDENKTNEYFQMCTPKNCPDNVFSSNYNFPYVINRMLYLALPPHIFVSTLKNYKKNCLNSKGTDKILLEKPFGNDLDSFKMLSKQILENFNEQQIYRIDHYLGKDMVSGLLKLKFTNTFLLSLMNRHFIKCIKITLKETKGVYGRGQYFDPYGIIRDVMQNHMLQLLTLITMEDPIDLNDESVKNEKIKILKSIPSIKLEDTIIGQYEKAENFKEDENNDDESKKNHSYHDDPHIDKNSITPTFCTCILYINSINWYGVPIIFKSGKGLNKDICEIRIQFHNIMGSSDENMNNNEFVIILQPVEAIYLKMMIKKTGCEEMEEVQLNLTVNEKNKKINVPEAYETLLLECFKGHKKKFISDEELYESWRIFTPLLKELQEKQVKPLKYSFGSSGPKEVFGLVKKYYNYGKNYTHRPEFVRKSSFYEDDLLDIN
What is the function of this protein?
Bifunctional enzyme which catalyzes the first two steps of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
What are the official names of this protein?
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase, PfGluPho.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glucose-6-phosphate dehydrogenase family.
Protein: DCUP_COXB1
Sequence: MLRLKNDRFIRALLRQPVDRTPVWIMRQAGRYLPEYRQLREKVPNFMAFCKTPELACEATLQPLRRFPLDAAIIFSDILTIPDAMGVDLHIAPTVGPVIRNPVRSAQDVNRLQMPAVEEALSYLFDAIRLAVKALDHRVPLIGFAGSPWTLACYMTEGQSSKTFLTARAMLYQQPDVFHTLLQKLTTLTIAYLNAQIKAGADVVMLFDTWGGLLTPSLYRQFSLDYLSQIAAEVVRQKNGRKIPLIFFTKNGGQWLESIANSGCDAVGLDWTTDIGQARRRVGDRVALQGNLDPAILLSNPESISTAAVDILKSYGQGSGHVFNLGHGIDPSTPIENVAALVEAVQNFSIKNEEPINSYYR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AB38G_ARATH
Sequence: MAHYRVSSEVENIMNRDRSHRKNEEEDEEEALKLAAMEKLQRLPTYDRARKAVLKGITGGFKEIDMKDLGLAERRELFDRVMTMDDEDWHGEYLRRLKSRFDRVSLHLPTIEVRFEDLNVTAEAYAGSKTVPTVLNSYVNLLKGIGTKIRVLPDRKKRISILNDVSGIIKPGRLTLLLGPPGSGKSTLLKALSGKTETGLRSTGKVTYNGHELHEFVPERTAGYIDQYDVHLPDLTVRETLKFSAKCQGVGTGYDMLAELLRREKDLNIKPDPYLDALMKASVIKGHKEYVVTDYVLKVLGLEICADTIVGNHMKRGISGGQKKRVTTGEMLVGPVGAFFMDNISDGLDSSTTFQIVKSIKQMIHVFDKTALISLLQPPPETFELFDDVIILGEGHIVYQGPREDVLEFFEFMGFKCPERKGIADYLQEILSKKDQEQYWANPELPYRYVTAKKFEEGFKIHHFGRAMRSQLATPFDRLKNHRAALTRTTYGASKLELLKACLERESILMKRNLRTFVLKSLQLIINAILIGVVFWQQKNYPSTVEDGIIYMGAIYLEVQMIVFSGFFELPMTIDKLPVFYKQRHFSFYPSWAFSLPTSIITFPLSFVEVFIVVLITYFTIGYDLTVPSFLKHYLVLALCGQMSYGLFRCIAAVTRNHVVSNTMGCLAVMWLMTFSGYVLSRNQVHKWLTWAYWTSPMMYIQTAVSVNEFRSESWKDGLGVAVLKSRGFFVETYWYWIGLLALILSTILSNIITSLCLAFLKQYGISKTAVLPDEREEADSNNTTGRDYTGTTMERFFDRVVTTRTCNDKKLRIPFKPLYMTFENITYSVDTPKEMKEKGIRENKLVLLNGLSGAFRPGVLTALMGVSGAGKTTLMDVLAGRKNTGYIQGEIYVSGFPKKQDSFARVSGYCEQSDIHSPLLTVYESLLYSAWLRLPPDIDTHTRELFIEEVMELIELKALREMLVGYVGISGLSTEQRKRMTIAVELVANPSILFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFESFDELFLLTRGGEEIYVGPIGHHSSQLIEYFEGIRGVGKIKEGYNPATWALEVTTRAQEDVLGVTFAQVYKKSNLYRRNKDLIKELNNIPPHAQDIHFSTKYSQSYLSQFQACLWKQHKSYWRNVPYNAVRFSFGAAVGIMYGIIFWSLGKRKGTRQDIFNSVGAMSTVVGFLSSQSAATVRPVVIAERTVFYREAGAGMYSALPYAFSQVIIEIPYTMAQACIYGVIVYGMIGYEWTASKFFLNIFFTFISILYSIYTGIMVISVSPNQEIASILNGVISTSWNVFSGFTIPRPRMHVWLRWFTYVCPGWWGLYGLTIAQYGDVETRLDTGETVVEFMKNYYGYEYNFLWVVSLTLIAFSMFFVFIYAFSVKILNFQKR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
ABC transporter G family member 38, ABC transporter ABCG.38, AtABCG38, Pleiotropic drug resistance protein 10.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RCAB_HORVU
Sequence: MASAFSSTVGAPASTPTIFLGKKVKNYYHGGNKMKSRVVRVMAAKKELDQGKQTDADRWKGLAYDISDDQQDITRGKGIVDSLFQAPMGDGTHEAILSSYEYISQGLRKYDFDNTMDGLYIAPAFMDKLIVHLAKNFMTLPNIKVPLILGIWGGKGQGKSFQCELVFAKMGINPIMMSAGELESGNGEPAKLIRQRYREAADIINKGKMCCLFINDLDAGAGRMGGTTQYTVNNQMVNATLMNIADAPTNVQLPGMYNKEENPRVPIIVTGNDFSTLYAPLIRDGRMEKFYWAPTREDRIGVCKGIFRTDNVPDEAVVRLVDTFPGQSIDFFGALRARVYDDEVRKWVGEIGVENISKRLVNSREGPPTFDQPKMTIEKLMEYGHMLVQEQENVKRVQLADKYLSEAALGQANDDAMKTGAFYGK
What is the function of this protein?
Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4. 1. 1. 39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
What are the official names of this protein?
Ribulose bisphosphate carboxylase/oxygenase activase B, chloroplastic, RA B, RuBisCO activase B.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO activase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GPMI_PARD8
Sequence: MSKKALLIICDGWGIGDKGKDDVIFNTPTPYWDELLKTYPASQLQASGENVGLPDGQMGNSEVGHLNIGAGRIVYQDLVKINIACRENTIMENPEIKRAYSYAKENNKQIHFMGLVSDGGVHSSLEHLLKLTDIAKEYGISKAYVHCFMDGRDTDPKSGKGFIEELENHLKTTGGKIASIIGRYYAMDRDKRWERVKEAYDLLVEGKGKQAECMVKAMEESYAEGVTDEFIKPIVHVENGKPVAVIEEGDVVIFFNYRNDRAKELTVVLTQQDMPEAGMHTIPGLQYFCMTPYDASFKGVHILFDKENVNNTLGEFLANVGKTQLHIAETEKYAHVTFFFNGGRETPFDSEERILVPSPKVATYDLKPEMSAFEVKDKLVDAINTKKFDFIVVNYANGDMVGHTGIYKAIEKAVVTIDACLHDTVEAAKANDYEVIIIADHGNADHALNEDGTPNTAHSLNPVPFVYVTANKDAKVEDGILADVAPSILHILGLKQPKEMTGKSLIK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: ACP_BLOFL
Sequence: MSIVEEKVKTIIAEQLGVKQEEVVNHASFVDDLGADSLDTVELVMALEEEFDIEIPDEEAEKITTVQAAIDFIHTNQK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_YERE8
Sequence: MSEQLLTASMPIDAAPLSDHAVATAAPATSKINLLDLNRQQMREFFAEMGEKPFRADQVMKWMYHYCYDDFEQMTDINKGLRAKLQRVAEIRAPEVAEEQRSTDGTIKWAIKVGDQQVETVYIPEGDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIIGAVKATGIRPITNVVMMGMGEPLLNLNNVVPAMDIMMDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPTDDIRDEIVPINRKYNIETFLAAVRRYLAKSNANGGRVTVEYVMLDHINDSTEQAHQLAECLKDTPCKINLIPWNPFPGAPYGRSSNSRVDRFSKVLMEYGFTTIVRKTRGDDIDAACGQLAGEVIDRTKRTLKKKMAGEPIAIKTV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWNA_BACSU
Sequence: MINSRLAVAIHILSLISMDEKTSSEIIADSVNTNPVVVRRMISLLKKADILTSRAGVPGASLKKDPADISLLEVYRAVQKQEELFAVHENPNPKCPVGKKIQNALDETFESVQRAMENELASKSLKDVMNHLF
What are the official names of this protein?
Putative HTH-type transcriptional regulator YwnA.
Protein: METI_YERPE
Sequence: MSEAMMWLMARGVWETLMMTFVSGFFGFVLGLPVGVLLYVTRPGQIIANNKIYRTLSGVVNIFRSIPFIILLVWMIPFTRMIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPSGLVEAARAMGATPMQIIKKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQLSGDRIVKAVTHK
What is the function of this protein?
Part of the binding-protein-dependent transport system for D-methionine and the toxic methionine analog alpha-methyl-methionine.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
D-methionine transport system permease protein MetI.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KHSE_THEMA
Sequence: MKVLVPATTTNLGAGFDVFGLALDLFNEVEFSFDTKETTIESTGKYASDLKDHNLFFEVLRFFERKTGYRVPPVRIKQTCNIPVSSGLGSSAAVIVAALHIANEGTGRNLSREDLMKLAVELEGHPDNVVPAFTGGLVVCYQNGSHLDFEKFEIDLSLTFLVPNFPVCTNEMRKILPEKVPFEDAVFNIKNSCQFLAKIAAGKIKEALKYVGDRLHQNYRINGNKKMKEFVEAILSKNPEYWFVSGSGPSVCSNINDFEGIPYLKDVLKLRVNNRGMIVSE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBOH_BURM7
Sequence: MTAIRGGSRRAPGLALALLGGVLLGACHGDENAQVNALPGFVSGSVRKTAYDGASDDLLTAGLGKTGLGSDTRPGFANPAQPSAAELRRLAIYSNYRALVDITPNGGYGRFWGPNVDLAGNDTLGEGKIAGTEYLAYSDDGSGRKNVTLLVQVPASFDPANPCIVTATASGSRGVYGAIAAAGEWGLKRGCAVAYNDKGGGNGAHEIGTGVVTLIDGTLATASSAGSSSLFTASESSSTLAAFNSAFPNRYAYKHAHSQQNPEQDWGLVTLQAVEFAYWALNEQFGPVVDGTRHGIRYRPGDITTIAASVSNGGGSALAAAEQDTRGWITAVVVGEPQINVRMTPGVTVEQGGAPVPSFGRPLADYATLANLLQPCAAAAVAATGAPYLSALPMGVTQSIRTQRCATLAAAGLVSGADTASQASDALAQLYAAGYLADSDLLQAPMWDSQAMPAIAVTYANAYTRSRVTDNLCNFSFATTNPVTGAVAAPAVSPMTNLFGAGNGVPPTNGINLVFNGASGGVDHRLATPDASFAGAFCLRQLWTANQLGIGTNVDAVRVAANLQHKPAIIVHGRSDALVPVNHASRAYVAQNSATEGRASQLSFYEVTNGQHFDAFLSVPGFDTRFVPVHYYDEQALNLMWNHLKSGAPLPPSQVIRTVPRGGVPGAAPALSTANLPPIVQSPGANAIAVNAGVIDVPL
What is the function of this protein?
Participates in the degradation of poly-3-hydroxybutyrate (PHB).  It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
What are the official names of this protein?
D-(-)-3-hydroxybutyrate oligomer hydrolase, 3HB-oligomer hydrolase, 3HBOH.
What is the protein family that this protein belongs to?
Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDR_KLEP7
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEDKLRSGMLKALEKRPVSADDVEMAVNHIKTHLRGTGEREVASKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLQD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: TYSY_SINMW
Sequence: MRQYLDLLEHVIETGTDRGDRTGTGTRSVFGYQMRFDLSQGFPVLTTKKLHLRSIIHELLWFLKGDTNIAYLKEHGVRIWDEWADENGDLGPVYGYQWRSWPTPDGGHIDQIATLVEGLKTNPNSRRHIVSAWNPALVDDMALPPCHCLFQFYVADGKLSCQLYQRSGDIFLGVPFNIASYALLTMMVAQVTGLEAGDFVHTLGDAHIYRNHFEQAQLQLTRTPKPLPRMEINPAVKDLFSFRFEDFELTGYEADSHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_MYCPN
Sequence: MESKWLTVDTKHLYGFDEAIFIQKYQKKVNQIHQQFLNQQLPDGHMNGWYSQPDQDHKGLLKQINTIAKQFNALKVTDIVYLGIGGSYTGIRAILDFLKPEQKANIKVHFVPDISAFNIAAVARAIKGKSWALVVTSKSGRTLEPAVTFRYFRNLLHKQYKQKHALRTVVITDAVKGLLVGMSNQYGYAHLTIPSNIGGRFSTLSPAGLLLAKLCGHDPKQLLLGTLTAKQELANSDLNTNSAYYYAALRHWLYTTKKLKIEVTVAYHSAYEYLLLQHRQLFGESEGKGGKSLFPTFSLFTTDLHSMGQLYQEGEKNFFETVIQVQTQFHDLELPPSDFNNDDQLDYLLAKSMNEISNTALEAVVEAHFQSNVNIIKLTLKERTTFMFGYFYFWLSMATMMSGSLLGHNVFDQPGVEVYKQLMFAKLGRE
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_LACLA
Sequence: MALNIENIVAELENATILELSELVKAIEEKFDVTAAAPVAAAAGAGDAAAAKDSFDVELTSAGDKKVAVIKEVRGITGLGLKEAKELVDGAPTMIKEGLSESEANEVKEKLEAAGASITLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y1838_STAAT
Sequence: MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDEFRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQIIVKPLDEIYAD
What are the official names of this protein?
UPF0342 protein USA300HOU_1838.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: UVRB_CUTAK
Sequence: MRPVTDITRRVAPFHVVSEFQPSGDQPQAIAELEKRVNSGEQDVVLLGATGTGKTATVAWLAERLQRPMLVMQPNKTLAAQFAQELRTFFPDNAVEYFVSYYDYYQPEAYIPQTDTYIEKDSSLNEEVERLRHSATNSLLTRRDVIVVSTVSAIYGLGTPQEYVDRMIPLEVGQEWDRDELLRDLVTNQYVRNDISGERGTFRVRGDTLEIFPVYEENALRVEFFGDEIEALTTMHPLTGEIISEDEQVYVFPATHYVAGPERMERAIASIQQELEERLAVLERDGKLLEAQRLRMRTTYDIEMMQQVGACAGIENYSRHIDGRAPGSAPNCLLDYFPEDFVLVIDESHVTVPQIGGMYEGDMSRKRTLVEHGFRLPSAMDNRPLKFDEFTQRIGQTVYLSATPGSYETERAHGVVEQIIRPTGLVDPEIIVKPTRGQIDDLMGEIRTRVDRGDGVLVTTLTKKMAEDLTDYLMEHGIRTRYLHSEIDTLKRIELLKELRMGEFDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSERSLIQTVGRAARNVNGQVIMYADQITDSMQVAIDETNRRRDIQMAYNKEHGIDPQPLRKKIGDITEMLAREGADTDELVEKFNYGKGQRGYNSMITDEQRAAQGRRLDVSKMAEEDLGKLIVDLTTEMRSAAGELKFEVAARLRDEIADLKKELRQMVEANR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.