PharMolix/UniProtQA huggingface dataset:
Protein: TIG_BRUO2
Sequence: MQVTETLNEGLKREIKVVVPAGDLEAKLAERLETARGRARINGFRPGKVPTAHLRKMYGKSFMAEIVNEILNDSSRSILAERNEKSATQPEVIMSEDEKEAEKVLDGKADFVFSLNYEVLPAIEVKDFSKIAVTREVVDISDEEVDEQVKRIASSTRTFETKKGKAENEDRVTIDYLGKLDGEPFEGGADNDAQLVLGSGQFIPGFEEQLIGLKAGDEKVITVTFPAEYGAAHLAGKEATFDIKVKEVAKPNELVLDDETAKKLGIESLERLRQVVREQIESQYGQITRQKVKRQILDALDGDYQFETPQKLVDAEFNNIWQQINFDLQQAGRTFEDEETTEEAAREEYRKLAERRVRLGLVLSEIGEKAGVEVTEEELQRAVYDQVRRYPGQEKEIYDFLRRTPDAVANLRAPIFEQKVVDHLLANINVTDKKVSKEELTAEDEDAASEAKPAKKAAAKKKAAPKKKAEEGKSEEA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: SIGM1_REOVJ
Sequence: MSDLVQLIRREILLLTGNGESANSKHEIEEIKKQIKDISADVNRISNIVDSIQGQLGGLSVRVSAIESGVSENGNRIDRLERDVSGISASVSGIDSRLSELGDRVNVAEQRIGQLDTVTDNLLERASRLETEVSAITNDLGSLNTRVTTELNDVRQTIAAIDTRLTTLETDAVTSVGQGLQKTGNSIKVIVGTGMWFDRNNVLQLFLSNQQKGLGFIDNGMVVKIDTQYFSFDSNGNITLNNNISGLPARTGSLEASRIDVVAPPLVIQSTGSTRLLRLMYEAVDFVVTNNVLTLRNRSVTPTFKFPLELNSADNSVSIHRNYRIRLGQWSGQLEYHTPSLRWNAPVTVNLMRVDDWLILSFTRFSTSGILASGKFVLNFVTGLSPGWATGSTEPSTTTNPLSTTFAAIQFINGSSRVDAFRILGVAEWNAGELEITNHGGTYTAHTNVDWAPMTIMYPCLG
What is the function of this protein?
Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor).  The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis.  Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis (By similarity).
What are the official names of this protein?
Outer capsid protein sigma-1, Sigma1, Cell attachment protein, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the orthoreovirus sigma-1 protein family.
What are the subcellular locations of this protein?
Virion. Note=Found in the outer capsid (36 copies).
Protein: YIDC_UREPA
Sequence: MSSVDKQNLTNRMRISVSHFAGASNANSIKKERKKKIFNVLLKVFKIIVYAFFLGIGLYGCFQNMANHWTINSTIVGNGFELGFHVDPILGANDIRFDLIYSGTGPWYPMSDFSFDYGPFYALFVWPIAQILLHFMYATRDWPAGLNAILGLIIILLIIRVITMLISARATIQTERISEIQGKIAEINAKYKDAKDMQSRQKKQMETKELYQKHNVKPLAPFESMIITLPIFLIIYRVVTILRPLKFISIFYIWDLSATPISEIFSNFTTSGWPYIFFLLIIIPVQILSQKIPQLLARKRNRNATTVGAKNKQQLKRVRMTQNIIAIVLAVVVAISASGIGLYWFFNAIFTILQSYIIHVIIMKRRSNSATRIESKLAKLGIS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRMA_XYLFT
Sequence: MAFLEVSVQCQERSQARYEEVLESFGALAVTLLDADADTVRERGVFEPGVGETVLWDVVVLSALFPVETDALGLLAGLEGAEPGLDWGGVRFRVVVDEDWERVWMDQFQAMRFGERTFIVPWNQAVPVEASGMDAAVVRLDPGLAFGSGTHPTTGLCLRWLDRLGGDGVLGGGDVLDFGCGSGILALAALKLGAVYAVGVDNDPQALLASRENALRNRVAERLEVYLPAEAPVRRYPVVVANILASTLVALAERLAGYVAPGGRLALSGILRGEEEEVLRCYAVWLDVLGCEEEDGWIRIDGVRRC
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_PSEPK
Sequence: MKSVEEQLALIKRGAEEVLVESELVEKLKRGQPLRIKAGFDPTAPDLHLGHTVLINKLRQFQDLGHQVIFLIGDFTGMIGDPSGKSATRPPLTREQVLENAETYKQQVFKILDPAKTEVAFNSTWMDKLTPADFIRLASQYTVARMLERDDFDKRYTTNQPIAIHEFLYPLVQGYDSVALKADVELGGTDQKFNLLMGRELQRSYGQEAQNIVTMPLLEGLDGVKKMSKSLGNYVGIQEAPGVMYSKLVSIPDTLMWRYFELLSFRSMEEIEQFRADVANGANPRDIKIKLAEEIVARFHGEEAAANAHRAAGNRMKEGELPEDLPEIEVAAAEDLPIAAVLNRAGLVKNSAQARDLLNSGAVKVDGAVVDKDFMFVLGATHVCQAGKKSFGRVTLKAE
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4HPE2_BURM1
Sequence: MTIHGFTCIEGHTEGMPVRMVIDGAPTLQGATMNARREDFVAHHDWVRRTLMLEPRGHAHMSGTIFYPPVSDNADFSLLFIETSGCLPMCGHATIGSIAFAIEERLVVPKRPGTVTVDVPAGQIVARYQTDGERVTSVRFTNVPSFLLKRDVEIAIPALGTLAVDIAYGGNFYPIVEVQPNFPGCEHFTPDELLAWGRDVQRAVGDALEVVHPDNPAIRGVRHCMWTGKPIADDAHGRAVVIAGDSLVDRSPCGTGSSARVAQRFARGWLKEGEAYCHESLIGSRFIGRVESTVRLESGVDAVLSSIEGRAWVTGRAQYRVDPSQPYALGFSLQEFVN
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase 2, 4Hyp 2-epimerase 2, 4HypE 2.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: Y639_MYCPN
Sequence: MLGSMALKLRKWIWASIPSLALILSSCSALVASVELKSLSELQNLADRNTELTKNKRTLITTLRESYGLNPKGTLNLLFEGWRYTLLSQRILERWQTEVGRFAKSFGNGSNQNSVQPNATLKGLKLSERSTTEIQLLAEQAITVSKQEVKEFTYKVESNKQFEATVKIKADLKIDPTKAMSHIENIFKDDETKKKDAQNSLTMSMGQNEALEATFTYSPATQGIFGRASFDRFTSNIKLNTKLRIQVSSTSDLMKKLLENSLTSSLKDQSFDNEGVNLFPYTLFALL
What are the official names of this protein?
Uncharacterized protein MPN_639.
What is the protein family that this protein belongs to?
Belongs to the MG439/MG440 family.
Protein: SYDND_CHRSD
Sequence: MRSHYCGQLNETLVDEEVALCGWVHRRRDHGGVIFLDLRDRDGIAQVVVDPDTPEAFANADRARNEFVLRIRGRIRLRPEGTQNAHMPTGMIEVLAKDVEVLNTAATPPFQLDEHGKVGEEIRLKHRYIDLRRPEMIDKLRLRSRITHSVRAYLEGQGFLDIETPILTRATPEGARDYLVPSRTHAGEFFALPQSPQLFKQLLMVSGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASFVEESDIMSLTEDMIRRLFQDVLDVELPAFPKMPYSEAMNRYGSDKPDLRIPLELVDVDDLMQGVDFKVFSGPAKADDGRVAALKVTGGATLSRKEIDAYTDFVNIYGAKGLAWIKVNERAKGIQGLQSPIVKFMEDIIESLLDRVGAEDGDIIFFGADKARIVNEALGALRVKLGEDLDLYTQAWAPLWVVDFPMFEADDNGRLAALHHPFTAPSCTPEAFKADPANALSRAYDMVLNGTELGGGSIRIHDQTMQRAVFEVLGIGEEEADEKFGFLLDALKFGAPPHGGLAFGLDRLVMLMSGARTIREVIAFPKTQSAACLMTDAPGEVSAEQLKELNIRLRQKAQNNGDV
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_BTV10
Sequence: MVAITVQGAQLIKRVVERFYPGIAFDINEGACYIYKFSDHIRRIRMKHGTKYRRQAEEIMRSISLRKERLYGIPVLDEVEWKYVFDGQTFQSYAFEVYVNSILPWSELDPEEEFLRNYRVSRETTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIELNPIPLGMQVMADFVNRFNSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEDISALEFGDIKIDPVGLLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRYKALFRSSFYNESRRMNEEKILEAVKYSQNLGSHDRRLPLFEKMLKMVYTTPFYPHKSSNMILASFLLSIQTITGYGRAWVKNVSTEFDKQLKPNPSNLVRDVSDLTREFFKQAYVEAKERREEMVKPEDLYTSMLRLARNTSSGFSTEIYVKKRFGPRLRDKDLVKINSRIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITRPDYKKIGGKVIVGDLEATGSRVMDAADCFRNSADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRALRYEGYTLEQIIDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDKGSFKVPKGVLPVSSVDVANRIAVDKGFDTLIAATDGSDLALIDTHLSGENSTLIANSMHNMAIGTLIQRAVGREQPGILTFLSEQYVGDDTLFYTKLHTTDITVFDKVAASIFDTVAKCGHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKTTFIGAWKMKRTIKENAMYRDRKFDSNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIMAPIRRIVHDIPPCWNETQGDKRGLISATKLSFFSKMARPAVQAALSDPQIMNLVEELPLGEFSPGRISRTMMHSALLKESSAKALLSSGYRLEYQKALNGWIAQVSMRLGEESGVISTSYAKLFDVYFEGELDGAPYMFPDQNLSPQFYIQKMMIGPRVSSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLGTNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKLLKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDAISLYCTQMVMLRAALGLPKKKMKIVVTDDAKKRYKIRLQRFRTHVPKIKVLKKLIDPNRMTVRNLENQFV
What are the official names of this protein?
RNA-directed RNA polymerase, VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
Protein: THRC_HAEIN
Sequence: MNLYNIKHPEEQVTFSQAVRQGLGRDQGLFFPEVIPQLNNINELLELPLVERSQKILGALIDGELPQATLDAMVKNAFTFPAPLEKVEENIYALELFHGPTLAFKDFGGRFMAQALAAVRGDGKITILTATSGDTGAAVAHAFYGLENINVVILYPKGKISPLQEKLFCTLGGNIRTVAINADFDACQALVKQAFDDVELRQAIGLNSANSINISRLLAQVCYYFEAVAQLPKEKRDNVVVSVPSGNFGNLTAGLIAKTLGLPIKRFVASTNANDTVPRYLKSGNWDPKTTVATLSNAMDVSRPNNWPRVEELFKRNGWDLTDLGSGMLSDSETEDTLKAMQSKGYLCEPHGAIAYQVLKDQLKASETGIFLCTAHPAKFKESVERILGIQLPLPETLDKHNQLPLLSDEMDNDFAQLRAYLLKS
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: SSRP_PELTS
Sequence: MAVKVVTENRRARHEYHILETFEAGLALRGTEVKSLRAGKASLQDSFARVENGELLLYNMHISPYEQGNQFNHEPKRTRRLLMHKYEILRLMGKTREKGLALIPLKVYFKNGLAKIELALAKGKKIYDRREDIASRDARREIDRAIKERMRLH
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RBFA_COPPD
Sequence: MKPLRKERLQQAIKQELSKILLEDMNDERLKFVTITDVELSDDQKYLKVYFSTMPGKNSEQILQSLERVKGYVSGEVARTLRLRFAPEIKFELDNSIERGVRMVKLLEDLEKKDEVKEDESHEDESTDHTEETNEEP
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y429_METAC
Sequence: MKTLVFNPFSGAAGDMILACALDLGADKQAVKELVEASAPVSMDIREVVKEGIKALDVRIKVPENEHVRTYPEIVDLVKAAKLPLQLEASTLSIFLKMAEAEAAVHGQPDLEMLHFHEVGQSDALADVIGSSAALHSLNCDSVYCTPINVGSGTIECAHGTLPVPAPATLEILRKGKLYFRGGSVNKELLTPTGAAILSHFAKPVETFPQGKAIAIGYGAGNADLPGPNVLQGVLLEPDSHLISDIIEVLETNADDVSGEVLGNLFEELLSMGARDVAIMPATMKKGRPAHIIKVIAKPEDSAKLARKIIVETGSLGVRVMPARHRLMAARNIERIKIELEGQEFETAVKVARDSEGVLLNISAEFEDCKKIAKASGIPVREIMRRTEEVARKLFS
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: HCD2_BOVIN
Sequence: MAAACRSVKGLVALITGGASGLGLATAERLVGQGATAVLLDLPNSDGETQAKKLGKSCAFAPADVTSEKDVQAALTLAREKFGRVDVAVNCAGIAVASKTYNLKKSQAHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPMGIRVMTIAPGLFGTPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQAIIENSFLNGEVIRLDGAIRMQP
What is the function of this protein?
In addition to mitochondrial dehydrogenase activity, moonlights as a component of mitochondrial ribonuclease P, a complex that cleaves tRNA molecules in their 5'-ends.  Together with TRMT10C/MRPP1, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity.  The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; HSD17B10/MRPP2 acting as a non-catalytic subunit.  The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme.  Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
What are the official names of this protein?
3-hydroxyacyl-CoA dehydrogenase type-2, 17-beta-estradiol 17-dehydrogenase, 2-methyl-3-hydroxybutyryl-CoA dehydrogenase, MHBD, 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)), 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, 3alpha(or 20beta)-hydroxysteroid dehydrogenase, 7-alpha-hydroxysteroid dehydrogenase, Endoplasmic reticulum-associated amyloid beta-peptide-binding protein, Mitochondrial ribonuclease P protein 2, Mitochondrial RNase P protein 2, Short chain dehydrogenase/reductase family 5C member 1, Short-chain type dehydrogenase/reductase XH98G2, Type II HADH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein: RLME_TREPR
Sequence: MGRTSEWYARHVGDSFVRTSKAWGYRARAACKLKRLDAKYGLMSRQCDVLELGSSPGVWSQYISYERRVSGMAWRTVSVDTRAMVRVRGVSFIHGDITEAETMAEVSSRLPSGVGLILSDICPHPSCERYLDSIATAKVAETLLMVSRRFLLDGGALLHKTFVIRAEHIASVMERHFSSVEVYRDASSRSFNSEAYLLCVGD
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUV2_HUMAN
Sequence: MFFSAALRARAAGLTAHWGRHVRNLHKTVMQNGAGGALFVHRDTPENNPDTPFDFTPENYKRIEAIVKNYPEGHKAAAVLPVLDLAQRQNGWLPISAMNKVAEVLQVPPMRVYEVATFYTMYNRKPVGKYHIQVCTTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGACVNAPMVQINDNYYEDLTAKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLTSLTEPPKGPGFGVQAGL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial, NADH-ubiquinone oxidoreductase 24 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GCS22_MYCS2
Sequence: MRECRSQEASGQLTFAKTPRTVGIEEEFHLVDLTTRRLATRAPELLPLLPDGYVAELQSCVVETNGSVVSTLPELRADLTARRRVLVDTAATLGLGVVAAGAVPLSVPSEMRVTQTSRYQQMLADYQLLAREQLICGTQIHVGIDDPDESVLVAGRVAAYVPTLLALSASSPFWSDGSDTGYSSVRTLVWQRWPTTGLAPPATSAAEYDALISDLIATGVITDAGMSYFDVRPALRTPTLELRVCDSCPRADTIVLIAALFRALVEREIEGLRAGVPAAIVVPPLGRAALWRAARSGLEGDLVDLIHPASRPAGDVVTDLVQMLRPQLEASRDWQTVEELARRALAEGSSAARQRRAMRMRNSLLDVVDHLIAETADVATVANDALPTQRNGSDRG
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-2, Gamma-glutamylcysteine synthetase 2-2, GCS 2-2, Gamma-GCS 2-2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: SYS_BACSU
Sequence: MLDTKMLRANFQEIKAKLVHKGEDLTDFDKFEALDDRRRELIGKVEELKGKRNEVSQQVAVLKREKKDADHIIKEMREVGEEIKKLDEELRTVEAELDTILLSIPNIPHESVPVGETEDDNVEVRKWGEKPSFAYEPKPHWDIADELGILDFERAAKVTGSRFVFYKGLGARLERALYNFMLDLHVDEYNYTEVIPPYMVNRASMTGTGQLPKFEEDAFKIREEDYFLIPTAEVPITNMHRDEILSGDSLPINYAAFSACFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYEELEKLTNQAERVLQLLELPYRVMSMCTGDLGFTAAKKYDIEVWIPSQDTYREISSCSNFEAFQARRANIRFRREAKGKPEHVHTLNGSGLAVGRTVAAILENYQQEDGSVVIPKVLRPYMGNREVMKP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_THEM4
Sequence: MRFSQLYAPTLRENPADAEIPSQALLQRAGFIRKIAAGVYTYLPLARRTLLKIENIVREEMDRIGAQEILMPIIQPAELWIKSGRWDDYGPEMMKLKDRHNRDFTLGPTHEELVTELVKNELNSYKQLPVTLYQIANKYRDEIRPRFGVLRAREFIMKDAYSFHDSWESLDEVYKKFKEAYSRILERIGLRYTVIEASSGAIGGKESHEFVAFAEYGESNILYCDCGYAGSDEKVPYMGEYEVFDEDEKERELVHTPNVRTVEEVAQYLGVEIKRIVKSLIFKGRDGYVMVLVPGNRELNFEKLKAYLGDQSLQMALPENILEDFGVPIGFLGPVGISNVKIVADKGIKYMKNFVVGGMKKNYHYINVNLERDFQVEEWADLVVVNPGEPCPVCGKPLKSERGIELGHIFKLGTKYSETMDVKYMNKDGKMKPFIMGCYGWGISRTLGAIVEQLHDDNGIIWPVSVAPYEVVITVVGKENEKSFAEKLYRYLLDKGVDVLIDDRDVSPGVKFKDADLIGFPLRITIGKSYKDGKVELKERVGNVTIIEADEEVILKNVQHILKR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_ECOUT
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLNDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MOAC_ROSCS
Sequence: MSDLTHLDETGKARMVDVGAKDETLREAVVRGEVHMRPETLQRLAAGDMPKGDALATARIAGIMAAKRAPDLIPLCHPLLLTHVAVDVRLDAATSTVQIEATVRTVGKTGVEMEALTAVSVAALTVYDMCKAIDRTMQIGAIRLVRKSGGRSGEIVCE
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: EFTU_LEUCK
Sequence: MAKETYVRTKPHVNIGTIGHVDHGKTTLTAAISKVLAEKQGITATDFAEIDNAPEEKERGITINTSHIEYETETRHYAHIDAPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLARQVGVEYLVVFLNKTDLVDDEELVELVEMEVRELLSEYDFPGDDIPVIKGSALKALEGDPEQVKVIEELMDTVDSYIPEPKRETDKPFLMPVEDVFTITGRGTVASGRVDRGVLTTGTEIEIVGLKDEIKKTTVTGIEMFRKTLDEAQAGDNIGALLRGVDRNEIERGQVLAKPGSIKTHKKFKAEVYVLSKEEGGRHTPFFTNYRPQFYFHTTDVTGVVELPAGVEMVMPGDQVTFEIELISPVAIEQGLKFTVREGGHTVGAGTVTEIED
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1703_LISMO
Sequence: MNQNPVEEGQKFPLTIRRMGINGEGIGYFKKAVVFVPGAITGEEVVVEAVKVRDRFTEAKLNKIRKKSPNRVTAPCPVYEACGGCQLQHVAYSAQLELKRDIVIQSIEKHTKIDPTKLKIRPTIGMEDPWRYRNKSQFQTRMVGSGQVETGLFGANSHQLVPIEDCIVQQPVTIKVTNFVRDLLEKYGVPIYDEKAGSGIVRTIVVRTGVKTGETQLVFITNSKKLPKKREMLAEIEAALPEVTSIMQNVNQAKSSLIFGDETFLLAGKESIEEKLMELEFDLSARAFFQLNPFQTERLYQEVEKALVLTGSETLVDAYCGVGTIGQAFAGKVKEVRGMDIIPESIEDAKRNAEKNGIENVYYEVGKAEDVLPKWVKEGFRPDAVIVDPPRSGCDQGLIKSLLDVEAKQLVYVSCNPSTLARDLALLAKKYRIRYMQPVDMFPQTAHVETVVLLQLKDK
What are the official names of this protein?
Uncharacterized RNA methyltransferase lmo1703.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.