PharMolix/UniProtQA huggingface dataset:
Protein: AEX1_CAEEL
Sequence: MREEALESICAALSISFTEDPDHLESIIDRFSEIFKVKDHLNQLRKKCEKFQTFTLEIRPVGSSNCTENVYAYIIESETCRQLELKPTGTTKLEIGSDKNVSLKFGLSQKKDSTTSKKGLSRSASLLKKLKFSDKKNLDELKISIFPLDIAVRKNINLGSGKSTLLEMKLIRNDHRNMIQCLEFDDFLEMTRSFHEWQAQISESELYDGSLGDPTFSMFYSIAFFFEIPSFVLKLTEMTCFLVWDDEMKKLDERALADVSLKMTACESEVDLQHPLLSPALSYLNDCTCNTIRCILVPFSTEPFFPPVSPSRLKSINVALKLIADICVLDVWDEFENLANPSNFLSSELKKLLESSAERYGESLKKQEFNELCRTILNLWMSLSNESQPYYIFFHQFDINYIGAAMLKLDKYLAESIQISLKCQLDLLNLRIPTELENFTKTTMRLFVTLRNLLNMVEAFHLPECQLFHFEEWFTDISVFWTYSWREVTLQMVERTITLDEDGDSVKYGARRPLPAGLYSFLCIQKGISDDLARLEFTFPHHLVVCAASVVNIMCQNINAYARKLFSEAMRNHEEKASRLVRATNGIEQAMCFVEEGYRRFAQFQRLEEYVDVDDLSAVRSTSIRLLKSTRDTCEIQVSTLLSHFVNLKTDIVLKIAKNLCADGKESNSGLKSYMRELASSERIESILECCYGLVDDVRCLLLPNCFKLSTQHFATSLEQQIRKNIRQKQPAEYYSNIYVGFLNILIFKRLKQMYLKFQIALKYIYEFLEIEDRKDIELLSNLHLNSFSTKDLILSYYDSLCEKIDRTRFGNAPHVDVHISYVKMVDEDTISIQIKLIKMSPIEWIDVISDRVDYFVRLELFPKILFPSNKFESPTTNPMPQSTRPQWKQLFEIRVPLECFFLRGACLAISVFDHERFIDRLVGRGFISLHSVPQASEEKPTQRLQVPLLPNDFSDQNNVFYQLLKTRACRDSIAKEFIETRTRRHQRIRALQHYIRINRNRVGHMLLG
What is the function of this protein?
Involved in retrograde signaling from post-synaptic cells to pre-synaptic neurons, probably by regulating vesicle exocytosis in post-synaptic cells (PubMed:11804572, PubMed:2323555, PubMed:19028454).  Acts in muscles, to regulate the localization of synaptic vesicle fusion protein unc-13 likely during vesicle exocytosis and thus regulate retrograde signaling at the neuromuscular junction (NMJ) (PubMed:11804572).  Regulates anterior body muscle contractions (aBOC) and the expulsion steps during the defecation motor program (DMP) (PubMed:11804572, PubMed:2323555, PubMed:19028454).  Probably by regulating DMP, plays a homeostatic role in the uptake of triglycerides (PubMed:25849533).  Regulates locomotion (PubMed:11804572).
What are the official names of this protein?
C2 domain-containing protein aex-1.
What is the protein family that this protein belongs to?
Belongs to the unc-13 family.
Protein: REP_CLVK
Sequence: MRTPRFRIQAKNVFLTYPKCSIPKEHLLSFIQTLSLQSNPKFIKICRELHQNGEPHLHALIQFEGKITITNNRLFDCVHPSCSTSFHPNIQGAKSSSDVKSYLDKDGDTVEWGQFQIDGRSARGGQQSANDAYAKALNSGSKSEALNVIRELVPKDFVLQFHNLNSNLDRIFQEPPAPYVSPFPCSSFDQVPVEIEEWVADNVRDSAARPWRPNSIVIEGDSRTGKTIWARSLGPHNYLCGHLDLSPKVFNNAAWYNVIDDVDPHYLKHFKEFMGSQRDWQSNTKYGKPVQIKGGIPTIFLCNPGPTSSYKEFLAEEKQEALKAWALKNAIFITLTEPLYSGSNQSHSQTSQEASHPA
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep, 40.4 kDa protein, Protein AC1, Protein AL1.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: EBRA_BACSU
Sequence: MLIGYIFLTIAICSESIGAAMLKVSDGFKKWKPSALVVIGYSLAFYMLSLTLNHIPLSLSYATWSGAGTVLTTVIGVKWFKEDLNAKGLIGILLLLSGVVLLNWP
What is the function of this protein?
Part of a multidrug efflux pump.  Confers resistance to cationic lipophilic dyes such as ethidium bromide, acriflavine, pyronine Y and safranin O.  The efflux is probably coupled to an influx of protons (By similarity).
What are the official names of this protein?
Multidrug resistance protein EbrA.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. EbrA/EbrB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL18_RALSO
Sequence: MNKNDSRLRRARQTRLKIAELNVARLAVHRTNLHIYAQVFSEDGTKVLASASTAEAEVRKELNGNGGNTAAATLVGKRIAEKAKAAGIEAVAFDRSGFRYHGRVKALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL30_OCEIH
Sequence: MSKKLEITLNRSVIGGTGVQKKTVEALGLKKIRQSVVREDTPAVRGMVNRVSHLLTVKEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RS8_BRASB
Sequence: MSTHDPISDLITRIRNAQMRSKSKVTTPGSKMRASVLEVLKSEGYIRGYATLEHPSGRSEIEIELKYFDGEPVIREIERVSKPGRRVYTSVKNLPRVNNGLGISVLSTPKGIMADHSARDANVGGEVLFTVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CMOA_NITSB
Sequence: MEKDKVFAKPIEKRFEFDEEVASVFDDMIARSVPFYKENMALVRDIVVKNVVQKDRVYDLGCSTGSLLIDIAKRSPFSLELIGLDSSEAMLQRAHHKAKAFGVSIDFQKADIISYAYKPAKIFISNYTLQFIRPLKREPLVQKIYDALVDEGIFVFSEKVISADKTLDKQLLDIYFDFKKKQGYSDFEIAQKREALENVLVPYTLEENMEMVKKCGFGFVEPIFRWANFVTFVAIKRKK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RS20_STAA8
Sequence: MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: YIDD_ANASK
Sequence: MIRAALVLLVRIYQRLVSPLLPPACRFYPSCSAYAVTALQRHGALRGSWLTVRRLCRCHPFHAGGVDPVPELTPKR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: WRT5_CAEEL
Sequence: MCSMWLMASWLMAFVAGSTLADYCGDHKVPFGMEVHKNGNVNILCSRPSCHEKKYAECPERATSTTCSTNSSWVGGVTQHSDGSLRLMCCEYDLLPTYSTIQYEKLTIRTGEYFEGDEQMEGDVVTAFDLIGNIEQVKEPDGKYSYNLLIYRYHCGNIPDTPPAWYMKKQWPYWEK
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.
What are the official names of this protein?
Warthog protein 5.
Protein: Y2072_ARCFU
Sequence: MREAKDGVLISVHVSPGSKEVSFSYDEWRRAVEVRIKSPAKEGKANRELLGIFRQIFGEVELVSGEKSRSKVLKGKRE
What are the official names of this protein?
UPF0235 protein AF_2072.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: SYT_STRZT
Sequence: MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKLIDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGFYYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIEEHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIYGTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRELERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPMNCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTPEQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAALDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADGEDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVAKKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQTVSVDNFVQAILADIANKSRVEK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAM1_KLULA
Sequence: MSQRPNTPQRDRPTEYRLSLSSNASSRRSSLGNNGRDQHASNQTMIEKYVLPQLQELSDSMVTLDGNMTHMNFIHESIADLNEALSALLYGLMCNSWCVDFPNISHDTPHELKLIQRLEELKQERQALQAKLKPKELTKGSILPLSRQPLSRGSQMLYRDENVPGSTASSNVNIDINDDEDNTAASFVSNPTTFKPQMISSVGASTDFMGKQTVGSASSKLRRRSILHQIRNNAAIGTIPNTLTGITPGERKRSLAVSAKRIPILAGSSTTAGSASSANRESTNTEPALPNRVVRTRQRTYNPKNLASRPPFR
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit DAM1, Outer kinetochore protein DAM1.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: RL21_YERPN
Sequence: MYAVFQSGGKQHRVSEGQTIRLEKLDIATGETIEFDQVLMIANGEEINIGAPLVDGGKIKAEIIAHGRGEKIKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: C77A4_ARATH
Sequence: MFPLISFSPTSLDFTFFAIIISGFVFIITRWNSNSKKRLNLPPGPPGWPVVGNLFQFARSGKPFFEYAEDLKKTYGPIFTLRMGTRTMIILSDATLVHEALIQRGALFASRPAENPTRTIFSCNKFTVNAAKYGPVWRSLRRNMVQNMLSSTRLKEFGKLRQSAMDKLIERIKSEARDNDGLIWVLKNARFAAFCILLEMCFGIEMDEETIEKMDEILKTVLMTVDPRIDDYLPILAPFFSKERKRALEVRREQVDYVVGVIERRRRAIQNPGSDKTASSFSYLDTLFDLKIEGRKTTPSNEELVTLCSEFLNGGTDTTGTAIEWGIAQLIANPEIQSRLYDEIKSTVGDDRRVDEKDVDKMVFLQAFVKELLRKHPPTYFSLTHAVMETTTLAGYDIPAGVNVEVYLPGISEDPRIWNNPKKFDPDRFMLGKEDADITGISGVKMIPFGVGRRICPGLAMATIHVHLMLARMVQEFEWCAHPPGSEIDFAGKLEFTVVMKNPLRAMVKPRI
What is the function of this protein?
Catalyzes the epoxidation of physiological unsaturated fatty acids in vitro.  Can use laurate, oleate, linoleate, linolenate and vernolate as substrate.
What are the official names of this protein?
Cytochrome P450 77A4, Fatty acid epoxidase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CCZ1_MOUSE
Sequence: MAAAAAGPGAWAAQEKQFPPALLSFFIYNPRFGPREGEEENKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPSKPAKSLHTQKNRQFFNEPEENFWMVMVVRNPIIEKQSKDGKAVVEYQEEELLDKVYSSVLQQCYSMYKLFNGTFLKAMEDGGVKLLKERLEKFFHRYLQTLHLQSCDLLDIFGGISFFPLDKMTYLKIQSFINRMEESLSVVKYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHIEPELAGRDSPVRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASTPLTLDFCRRLDSIVGPQLTVLASDICEQFNINKRISGSEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLTSVHPDLMKILGDINSDFTRADEDEEIIVKAMSDYWVVGKKSDQRELYVILSQKNANLIEVNEEVKKLCATQFNNIFFLD
What is the function of this protein?
Acts in concert with MON1A, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.
What are the official names of this protein?
Vacuolar fusion protein CCZ1 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCZ1 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: CH60_ECOL5
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKTLSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLB_SYNE7
Sequence: MKLAYWMYAGPAHIGTLRISSSFRNVHAIMHAPLGDDYFNVMRSMLERERNFTPVTTSVVDRNVLARGSQEKVIDNILRKDTEERPDLIVLTPTCTSSILQEDLQNFVERAKESAQCDVLLADVNHYRVNELQAADRTLEQIVRFYLDRAQRQGTLPSQRTEQPSVNILGMTTLGFHNRHDTTELQRLMADLGITVNAVIPAGASVEELQHLPRAWFNLVPYREVGLLTAQYLQDTFDQPMVAIAPMGITATADCIRQIQQVLNQQGAAVDFEPFIDRQTRFASEAAWFSHSIDCQNLTGKRAVVFGDNTHAAAFTKILSREMGIHVVLAGTYCKHDADWFEAEVAGYCDRVLISDDHNAIADAIAELEPAAIFGTQMERHVGKRLNIPCGVIAAPVHIQNFPVGYRPFVGYEGANQIVDLVYNSFTLGMEDHLLEIFGGHDTKEVLTKTVSAGSDLDWKPDGLTELNRIPGFVRGKVKRNTEKYAREQGLTAITAEVLYAAKEALGA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: C560_PIG
Sequence: MAALLLRHVGRHCLRAHLSPQLCIRNAVPLGTTAKEEMERFWNKNLGSNRPLSPHITIYRWSLPMAMSICHRGTGIALSAGVSLFGLSALLLPGNFESHLELVKSLCLGPTLIYTAKFGIVFPLMYHTWNGIRHLIWDLGKGLTIPQLTQSGVVVLILTVLSSVGLAAM
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial, Succinate-ubiquinone oxidoreductase cytochrome B large subunit, CYBL.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b560 family.
Protein: DJLA_ECOL6
Sequence: MQYWGKIIGVAVALIMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
What is the function of this protein?
Regulatory DnaK co-chaperone.  Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway.  The colanic acid capsule may help the bacterium survive conditions outside the host.
What are the official names of this protein?
Co-chaperone protein DjlA.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type III membrane protein.
Protein: COBS_PYRAE
Sequence: MRCLKSLLAFFTAFPIGGAELSFKCVWALPYVAAPIIAAIPTTLLYLGASPAIAYIALLAATGLHHLDGLADVGDALLVRDREAARRVLEDPRRGTGGIFAVTAVVVTTAAHLHSPLQLLLGEVFSKSTALLFAGFSKSFKPGLGEAFTEAAKRQWPAALPALAVLAYLAPVTTAVSLATSALLYQLAYRHLGGANGDVYGYLLEVSRSAFVIWSAYVPVPTAF
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOD_NEIM0
Sequence: MKGVYFVSGIDTDIGKTVATGVLAKQLLQQGKSVITQKPVQTGCQNIADDIAVHRKIMGKPMQEADKQGLTMPEIFSYPASPHLAARLDGRALDLDKIRTATQQLAAQYEIVLVEGAGGLMVPLTENLLTIDYIRQQGYPVILVTSGRLGSINHTLLSFAALKQYGIRLHSLVFNHIHDSRDAHIAQDSLNYLKCRLKADFSEAEWMELAKTDAV
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN32A_CANLF
Sequence: MEMGRRIHLELRNRTPSDVKELVLDNCRSIEGKIEGLTDEFEELEFLSTINVGLTSVANLPKLNKLKKLELSDNRISGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDDEEDEDEEEYDEDAQVVEDEEDEEEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEDVGEEERGQKRKREPXDXGEDDD
What is the function of this protein?
Multifunctional protein that is involved in the regulation of many processes including tumor suppression, apoptosis, cell cycle progression or transcription.  Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation.  In addition, plays a role in the modulation of histone acetylation and transcription as part of the INHAT (inhibitor of histone acetyltransferases) complex.  Inhibits the histone-acetyltranferase activity of EP300/CREBBP (CREB-binding protein) and EP300/CREBBP-associated factor by histone masking.  Preferentially binds to unmodified histone H3 and sterically inhibiting its acetylation and phosphorylation leading to cell growth inhibition.  Participates in other biochemical processes such as regulation of mRNA nuclear-to-cytoplasmic translocation and stability by its association with ELAVL1 (Hu-antigen R).  Plays a role in E4F1-mediated transcriptional repression as well as inhibition of protein phosphatase 2A.
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member A, Inhibitor-1 of protein phosphatase type 2A.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Shuttles between nucleus and cytoplasm. Translocates to the cytoplasm during the process of neuritogenesis (By similarity).
Protein: KIF27_RAT
Sequence: MEEIPIKVAVRIRPLLCKEVLHNHQVCVRDIPKTQQIIIGRDRVFTFDFVFGKNSTQDEVYSTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHVASVVDGQKGIIPRAIQEIFQSISGNPNIDFKIKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECQVDSVEDVMGLLQVGNAARHTGTTQMNEHSSRSHAIFTISVCQVGKSAEATEDGEWCSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHVPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPQADRMDEMEFEIKLLREALQSHQASISQTSQTASENVPDQNRIHSLEEQIAQLQEECLGYQDCIEQAFAFLVDLKDAVRLNQKQQHKLQQWFSRTQEVRKAVLTPLPGNQSIGNLEEGPQHVTVLQLKRELKKYQCALAADQVVFTQKELELEELRRQMQLMAQESKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELAKRSSSMPTSTKESCGDGPDARAPEKRPHTAPFDSHWGHYVYIPSRQDFKKVCSSSPVYSLDQVFAGFRTRSQMLMGHLEDQDEVLHCQFSDNSDDEDSEGQEKPRVRSRSHSWVKKPGSVCSLVEMSDTQAECQRSYLGNGDLKMESLQESQELNLQKLRTSELILNKAKQKMRELTINIRMKEDLIKELIKTGDNAKSVSRQYSLKVTKLEHEAEQAKVELTETRKQLQELEGKDLSDVALKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRASELEQNVDHLKYQKVQLQRRLREESEKKKQLDAEVKRDQQKLKELQLNAGQGEGLHPKAEDTDAFNLNRRKGPFRSVDQLQKLDEQRKWLDEEVEKVLSQRQELEMLEEELKKREAIVSKKEALLQEKSHLENKKLRSSQALSTDSLKISARLNLLDQELSEKSLLLENSPTEEKVKISEQVQALQREREQLQRQRNSVDEKLRHGRVLSPKEEHLLFQLEEGIEALEAAIEFKNESIQNRQSSLKSSFQNLSQSESNVLEKLVCLNIAEIRAILFKYFNKVINLREAERKQQLQNKEMKMKVLERDNMVHELESALEYLRLQCDRRLTLQQKEHEQKMQLLLHHFKDQDGEGIIETLNKYEDKIQQLEKDLYFYKKTSRDLKKRLKDPVQGAVQWQRTLTEHHDAGDGVLNPEEAAVLSEELKWASRTENTKLNGREKEVDNSSSSLKTPPLTQQILEDGPDSLPVCGSLAPSSGQLQSSADKTEAHAFTQSQSPPPPQLQPVRSIAQLQGVKPVKVCRRELRQISALELTLRRSSLGAGVRSVTADSLEEPEES
What is the function of this protein?
Plays an essential role in motile ciliogenesis.
What are the official names of this protein?
Kinesin-like protein KIF27.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF27 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Note=Localizes to centrioles and basal bodies.
Protein: P4548_PLAF7
Sequence: MMLYISAKKAQVAFILYIVLVLRIISGNNDFCKPSSLNSEISGFIGYKCNFSNEGVHNLKPDMRERRSIFCTIHSYFIYDKIRLIIPKKSSSPEFKILPEKCFQKVYTDYENRVETDISELGLIEYEIEENDTNPNYNERTITISPFSPKDIEFFCFCDNTEKVISSIEGRSAMVHVRVLKYPHNILFTNLTNDLFTYLPKTYNESNFVSNVLEVELNDGELFVLACELINKKCFQEGKEKALYKSNKIIYHKNLTIFKAPFYVTSKDVNTECTCKFKNNNYKIVLKPKYEKKVIHGCNFSSNVSSKHTFTDSLDISLVDDSAHISCNVHLSEPKYNHLVGLNCPGDIIPDCFFQVYQPESEELEPSNIVYLDSQINIGDIEYYEDAEGDDKIKLFGIVGSIPKTTSFTCICKKDKKSAYMTVTIDSAYYGFLAKTFIFLIVAILLYI
What is the function of this protein?
Gametocyte surface protein required for male fertility.
What are the official names of this protein?
Gametocyte surface protein P45/48.
What are the subcellular locations of this protein?
Cell surface. Cell membrane; Lipid-anchor, GPI-anchor. Note=Present on the surface of male and female gametocytes.
Protein: GMHA_TOLAT
Sequence: MYQELIKQELVTAQQALADFIADAENINAIERAATLIAASLRDGGKVMSCGNGGSHCDAMHFAEELTGRYREDRPGYAGIAISDPSHLSCVSNDYGYQYVFSRYLEAVGRPGDVMLGISTSGNSQNIITAIESAKAKGIKVVVLTGKDGGKMAGLADVEIRVPYFGYADRIQEIHIKVIHILIMLIEKELAV
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITD_OENOB
Sequence: MEIKKTALAGTTESSDIQITLSKGNDGIDVDLTSDVKKQFGDQIVKVITDTLNKFQITNAKVRAVDKGALDCVIKARTITAASRALNQEDQINWEVL
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.