PharMolix/UniProtQA huggingface dataset:
Protein: CUPA5_CANPG
Sequence: QLANEPPIEIIRQESTDNGDGNFNFLFETANGIYKEVSGYPTANGAQAMTGSFRFPLDDGQIVEVSFTADENGYLPVSDFIPTPHPIPAHVLETLAIVDELVRQGATWDEQGRRIT
What are the official names of this protein?
Cuticle protein AM1274, CPAM1274.
Protein: PHOSP_HRSVB
Sequence: MEKFAPEFHGEDANNKATKFLESIKGKFASSKDPKKKDSIISVNSIDIEVTKESPITSGTNIINPTSEADSTPETKANYPRKPLVSFKEDLTPSDNPFSKLYKETIETFDNNEEESSYSYEEINDQTNDNITARLDRIDEKLSEILGMLHTLVVASAGPTSARDGIRDAMVGLREEMIEKIRAEALMTNDRLEAMARLRNEESEKMAKDTSDEVPLNPTSKKLSDLLEDNDSDNDLSLDDF
What is the function of this protein?
Plays critical roles in regulating RNA replication and transcription through its interactions with multiple proteins.  Tethers the RNA-directed RNA polymerase L to the nucleoprotein-RNA complex.  Recruits the M2-1 protein, a processivity factor that is required for efficient transcription of viral RNA.  Acts as a chaperone for neo-synthesized nucleoprotein by forming an N-P complex that preserves N in a monomeric and RNA-free state and prevents the association of nascent N with host cell RNAs.  Recruits the host phosphatase PP1 to inclusion bodies to regulate viral transcription.  Together with the nucleoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway.
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the pneumoviridae phosphoprotein P family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Localizes in cytoplasmic inclusion bodies.
Protein: YML33_YEAST
Sequence: MESIILSIAIFIGVLLGTSVGTFSGSGISAGVGASSGSGISAGVGASSGSSTSVGVGTFGGSSTSVGVGTFGGSSTSVGVGTFSGSRTSPDVDAGSGSSTSPDVGAGSGSSISAGVGTFSGSRTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGISTTMNARVAVLITAAILSAPVTAIALLEARR
What are the official names of this protein?
Putative uncharacterized protein YML133W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TA10_TREME
Sequence: EHDPSAPGNGYC
What is the function of this protein?
Tremerogen A-10 is produced by the a mating-type cells and induces formation of conjugation tubes in a mating-type cells.
What are the official names of this protein?
Tremerogen A-10.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: Y732_ACTPJ
Sequence: MAKKRSKNEIDWTDEEEEIIWVSKSEIKRDSEHLKKLGAELIELTPQNLEKIPLDDDLKDAIRQAQSFKLEARRRQIQFIGKLLRNRDPEPIQEALDKVKNRHNQQQALLHKLELVRDQLVNMGDSSLEHLLTEHPQLDRQHLRNLIRGAQKEREANKPPKNYREIFQYLKTEIAE
What are the official names of this protein?
UPF0307 protein APJL_0732.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: Y630_CHLCV
Sequence: MAKIPYAILEKGSLLLASPDTDQGVFARSVILLCEHSLNGSFGLILNKTLGLEISDDIFTFDKVSNNNIRFCMGGPLQANQMMLLHSCSEISEQTLEICPSVYLGGDLSFLQEIAASESGPTINLCFGYSGWQAGQLEKEFLEGNWFLAPASYEYVFSDNPDNLWSRILKDLGGKYASLSTVPENLLLN
What are the official names of this protein?
UPF0301 protein CCA_00630.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: DNLJ_ECOHS
Sequence: MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKQWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MUTS_YERPY
Sequence: MKNNDKLDSHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYSDAKRASQLLDISLTKRGASAGEPIPMAGVPYHSIENYLTKLVQLGESAAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDAKGFGYATLDISSGRFRVAEPADLETMAAELQRTNPAELLYPENFEPMSLIEHRHGLRRRPLWEFELDTAKQQLNLQFGTRDLIGFGVEQAHLALRAAGCLLQYVKDTQRTSLPHIRGLTMERQQDGIIMDAATRRNLELTQNLSGGSENTLAAILDCSVTPMGSRMLKRWLHMPIRDIRVLTDRQQAIGGLQDIAAELQTPLRQVGDLERILARLALRTARPRDLARMRHAFQQLPEIHRLLQPIDVPHVQNLLSQVSQFDELQDLLERAIVETPPVLVRDGGVIASGYNAELDEWRALADGATDYLDRLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALAIEKGLYEEIFDLLLPHLPELQLSANALAELDVLANLAERAETLNYSCPTLSDKPGIKIMGGRHPVVEQVLKEPFISNPLTLSPQRRMLIITGPNMGGKSTYMRQTALIVLLAHMGSYVPADQATIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEQSLVLMDEIGRGTSTYDGLSLAWACAENLASRIKAMTLFATHYFELTTLPEKMEGVANVHLDALEHGETIAFMHSVQEGAASKSYGLAVAALAGVPRDVIKRARQKLKELESLSNNAAASTIDGSQMTLLNEEIPPAVEALEALDPDSLSPRQALEWIYRLKNMV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y893_MYCTO
Sequence: MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKLPDHYLTTGDFGEHFVNFQGARTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLADYHIRPRAQRRSVAVDLRDEWQIALCNNGFDANRPSAWIAEGLLVYLSAEAQQRLFIGIDTLASPGSHVAVEEATPLDPCEFAAKLERERAANAQGDPRRFFQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVPEADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFKRFEAD
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MT0917.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: PTPB_STAEQ
Sequence: MKIIFVCSGNTCRSPLAESIAKSLLPHDSIASRGLFAVEGQAISKESLELIHKYDLPEPSRAQAFHIDDLDADIILTMTQAHKDLIFSMYGRQSNVFTLNEYVGDTQEIDDPFGGSFDVYEQTYTKIYDLVDKIKFKHE
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpB, Phosphotyrosine phosphatase B, PTPase B.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: VGLU2_MOUSE
Sequence: MESVKQRILAPGKEGIKNFAGKSLGQIYRVLEKKQDNRETIELTEDGKPLEVPEKKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISDGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATSQENGGWPNGWEKKEEFVQEGAQDAYTYKDRDDYS
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate (PubMed:17108179, PubMed:33440152, PubMed:25433636, PubMed:11432869).  At the synaptic vesicle membrane, mainly functions as a uniporter which transports preferentially L-glutamate but also, phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:17108179, PubMed:11432869).  The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane (PubMed:11432869).  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane therefore affects the proton electrochemical gradient and promotes synaptic vesicles acidification (By similarity).  Moreover, functions as a vesicular K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular glutamate uptake (PubMed:25433636).  The vesicular H(+)/H(+) antiport activity is electroneutral (PubMed:25433636).  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation (PubMed:33440152).  The symporter activity is driven by an inside negative membrane potential and is electrogenic (PubMed:33440152).  Also involved in the regulation of retinal hyaloid vessel regression during postnatal development (PubMed:30936473).  May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas (By similarity).
What are the official names of this protein?
Vesicular glutamate transporter 2, VGluT2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse, synaptosome. Cell membrane; Multi-pass membrane protein.
Protein: URE3_MYCSS
Sequence: MRLTPHEQDRLLISYAADLARRRRARGLRLNHPEAVAVITDHLLEGARDGRTVAELMVSGRDVLGRDDVMEGVPEMLHDVQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_CLOTE
Sequence: MAKVQYYGTGRRKKSIARVRLVPGEGKVLINKRDEEEYFGLETLRVIVNQPLVLTGTKDKFDVLVNVYGGGLTGQAGAIRHGISRALLKADESLRPELKKAGFLTRDPRMKERKKYGLKKARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: TNR6_BOVIN
Sequence: MSGIWVHLSLIFISVSGPLSKGENAHMAGINSEGLKLNITEANSCQEGLYREHQFCCQPCPPGKRKNGDCKRDGDTPECVLCSEGNEYTDKSHHSDKCIRCSICDEEHGLEVEQNCTRTRNTKCRCKSNFFCNSSPCEHCNPCTTCEHGIIEKCTPTSNTKCKGSRSHANSLWALLILLIPIVLIIYKVVKSRERNKKNDYCNSAASNDEGRQLNLTDVDLGKYIPSIAEQMRITEVKEFVRKNGMEEAKIDDIMHDNVHETAEQKVQLLRNWYQSHGKKNAYCTLTKSLPKALAEKICDIVMKDITNERENANLQNENENLV
What is the function of this protein?
Receptor for TNFSF6/FASLG.  The adapter molecule FADD recruits caspase-8 to the activated receptor.  The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.  FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft.
Protein: UREE_PARMW
Sequence: MTQAVLVLDQRLAARADQADLLLPLTADERSVVRGRRRTDCGREVLLQLPRDGALQPGDQLSDAAGTARVEVTAATEALLRVRATSALALMQAAYHLGNRHVALELHEQDLYLLEDAVLATMLESRGLQLSRCQRPFRPEGGAYAGHQHG
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_HERA2
Sequence: MRDRLYTTEALIIRRSDVGEADRILTIYTPHHGKLSVTARGVRKMTSKLAGHLELFIHTRLQLAKGRSFDVVTESRVVQPFRSLREDLSRISQGYYVAELLDQMTPDESDNPALFRLTCETLAALDVLDDVVRRDVILRYYELHTLILSGYRPHLFDCANCERELSPDADRYSPITGGVLCQQCSSNEPRTLPINLNTFKLLRYLARMPLETVVSLVPAPATVQEARLVLKASLSQILERELKSTQFLNLVRG
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: FUCM_SALDC
Sequence: MLKTISPLISPTLLKVLAEMGHGDEIIFSDAHFPAHSLGPQVIRADGLSVSDLLRAIIPLFELDSYAPPLVMMAAVEGDTLDPSVEARYRDALSLEAPCPDIVRIDRYAFYERAQKAFAIVITGECAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_CLOTE
Sequence: MARQNKQEAIYEFIKEQLREKGYPPSVREICNAVELRSTSTVHGHLKRLEEKGVIRRDPTKPRAIEVLEHSIMKKEMVDIPVVGTVTAGKPILAVENIEDTFALPINYVRNKKQLFALKIKGDSMIDTGILDGDLAIVEKNNSVLNGEIVVALLGDRATVKRFFKEKDYIRLQPENETMEPIIVKQCEIIGKVVGVYRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: DCDA_AQUAE
Sequence: MELLKEYNPYLEYRDGELFIEGVSLKELAQTFGTPLYVYSSNFIKERFEAYRKAFPDALICYAVKANFNPHLVKLLGELGAGADIVSGGELYLAKKAGIPPERIVYAGVGKTEKELTDAVDSEILMFNVESRQELDVLNEIAGKLGKKARIAIRVNPDVDPKTHPYIATGMQKSKFGVDIREAQKEYEYASKLENLEIVGIHCHIGSQILDISPYREAVEKVVSLYESLTQKGFDIKYLDIGGGLGIKYKPEDKEPAPQDLADLLKDLLENVKAKIILEPGRSIMGNAGILITQVQFLKDKGSKHFIIVDAGMNDLIRPSIYNAYHHIIPVETKERKKVVADIVGPICETGDFLALDREIEEVQRGEYLAVLSAGAYGFAMSSHYNMRPRAAEVLVENGSVKLIRKRENYDYIVEPSLDI
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: IL1RA_MOUSE
Sequence: MEICWGPYSHLISLLLILLFHSEAACRPSGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNIKLEEKIDMVPIDLHSVFLGIHGGKLCLSCAKSGDDIKLQLEEVNITDLSKNKEEDKRFTFIRSEKGPTTSFESAACPGWFLCTTLEADRPVSLTNTPEEPLIVTKFYFQEDQ
What is the function of this protein?
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A.  Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
What are the official names of this protein?
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: ARGB_PARL1
Sequence: MPDTDKGAKPQDDSRLERARILSEALPFMQRYDKRTVVVKYGGHAMGDEELGAEFARDIVLLKQAGLNPIVVHGGGPQIGAMLNRLGIKSEFSGGLRITDKATVEIVEMVLAGSINKQIVAQLNQAGGRAVGLCGKDGNLVVARKVHQKVHDPESNIEKLLDLGFVGEPEKINPEILDVIQKSDIIPVIAPVGVSRDGHTYNINADTVAGAIAAAMGAARLLLLTDVTGVLGKDGKLIEALTVAEAKALMKDGTISGGMIPKLETCIESVEGGVEAVVILDGRVRHAVLLELFTELGAGTLIQK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_XANP2
Sequence: MSLKIRLARGGAKKRPYYRIVIADARSPRDGRFIEKIGTFNPLLAKDAENRVVLDADKAKAWLEKGAQPTDRVARFLDAAGLMKRDAKNNPKKGEPGEKAKERAKERAEKAAAGSTEDAAAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CBHC_EMENI
Sequence: MHYSASGLALAFLLPAIQAQQTLYGQCGGSGWTGATSCVAGAACSTLNQWYAQCLPAATTTSTTLTTTTSSVTTTSNPGSTTTTSSVTVTATASGNPFSGYQLYVNPYYSSEVQSIAIPSLTGTLSSLAPAATAAAKVPSFVWLDVAAKVPTMATYLADIRSQNAAGANPPIAGQFVVYDLPDRDCAALASNGEFAISDGGVQHYKDYIDSIREILVEYSDVHVILVIEPDSLANLVTNLNVAKCANAQSAYLECTNYAVTQLNLPNVAMYLDAGHAGWLGWPANLQPAANLYAGVYSDAGSPAALRGLATNVANYNAWAIDTCPSYTQGNSVCDEKDYINALAPLLRAQGFDAHFITDTGRNGKQPTGQQAWGDWCNVIGTGFGARPSTNTGDSLLDAFVWVKPGGESDGTSDTSAARYDAHCGYSDALQPAPEAGTWFQAYFVQLLQNANPSF
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.  Active against carboxymethylcellulose, beta-glucan and lichenan.
What are the official names of this protein?
1,4-beta-D-glucan cellobiohydrolase C, Beta-glucancellobiohydrolase C, Exocellobiohydrolase C, Exoglucanase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 6 (cellulase B) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RISB_THEYD
Sequence: MKIIEGKLEAQGLKFGIIVSRFNEFITSRLLEGAIDALIRHGAIEKDIEIVRVPGSFEIPLIAKKLAQSGRFHAIICLGTLIRGATPHFDYIAAEVSKGIALVSLETSIPVSFGIITADTIEQAIERAGSKSGNKGWDAALVAIEMAKVMGQLK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: LPXC_AERS4
Sequence: MIRQRTLKTSVQATGVGLHSGRKVTMTFRPAPVNTGIVYLRTDLDPVVALPANADQVRDTVLCTALVNEAGVRVSTIEHLSAALAGMGIDNLYVEVDAPEIPVMDGSAHPFIYLLQEVGIREQNAAKQFVRIKQSIRVEDGDKWAEFHPYRNGFKMDLEIDFQHPVFEGRNQRCVLDFSGASFVKEISRARTFGFMRDIEYLRSQNLALGGSLENAVVLDDYRVLNEDGLRCEDEFVKHKMLDAIGDLYMCNRSIIGEFRAYKTGHALNNKLLRALLAKQEAWELVTFEGEGAKAPIAYYDNGLVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: VWA5A_RAT
Sequence: MEHHWGLITGNKEKVPLKSISVTLSINDFVAAVAATLHYENEEKVPIEAMFVFPMDEDSAVYSFEALVDGKKIVAELQDKTKAHSKYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGTKVAVTLRYVQELPLESDGALRYLLPAVLNPRYQLSEQSASSCLNVQKPIVPLEALPYTLSMVATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYREVHSPSVAVEKGMQDKKRDSLMGAPCAMVSFYPDIPEVNASKVCGEFVFLMDRSGSMQTPMRTEENSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEQFFPESVKYTQETIEEAVERVKRLDADLGGTEILTPLRNIYKTSSIPGHPLQLFVFTDGEVSDTYSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAEFITGKDRMQAKALGSLKLALQCALDDISLSWELPPGLSVNMLSPEQPTIFRGQRLIIYAQLTGPMPQAESRGAVCLKHTLQGKSLENKVAFSLQPKENANFTIHRLAAKFLIQTKDLGSHEVSKEEKKDVMNISLQSGVLSSFTAFVAINKELNKPVQGPLAHRVIPRPMIATSTSMFMRSCSRLTGPFKNSRLKRRLCAADYVPYGHESTVYSSMPSPAPIENQGVADSSNEKSNSQNEHKAFGENVVLQLIFLQNANGSWKLDENLTKILGTTLEDTKAANPSQHGDPSAWATILAVLWLHANGQDLKCEWELLERKAVAWLHDHAGRGTTPPPFPSFHLHPREPCLYVLQRTQESLWLSQLCCLRTLSLQLILHFQD
What is the function of this protein?
May play a role in tumorigenesis as a tumor suppressor.  Altered expression of this protein and disruption of the molecular pathway it is involved in may contribute directly to or modify tumorigenesis (By similarity).
What are the official names of this protein?
von Willebrand factor A domain-containing protein 5A, Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog, Mast cell surface antigen 1, Masa-1.
Protein: SPC19_YARLI
Sequence: MTNTLDDSIGSMQNCVSIVRDTSLKLRSRAQTPEETERIKKVLQLTRKYEEVTQSEVLAAQQRQAAEIAPQVQDLIGGVEKQISSLHSKERKLKSQSELNKSRLEQFPMTRREVVDVPRDADNVVEVTEEELQELEELQREREKLKMEISRLNLEKRKSVYGKLPQ
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit SPC19, Outer kinetochore protein SPC19.
What is the protein family that this protein belongs to?
Belongs to the DASH complex SPC19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: CYB_SCYCA
Sequence: MATNIRKTHPLLKIVNHALIDLPAPSNISVWWNFGSLLGLCLIMQIITGLFLAMHYTADISMAFSSVIHISRDVNYGWLMRNIHAYGASFFFICIYLHIARGLYYGSYLNKEAWNIGVVLLFLLMATAFVGYVLPWGQMSFWGATVITNLLSAFPYIGNLLVQWIWGGFSVDNATLTRFFAFHFLLPFLILALSVIHILFLHETGANNPMGINSNTDKISFHPYFSYKDLFGFLIVITLLATLALFMPNLLGDAENFIPANPLVTPLHIQPEWYFLFAYAILRSIPNKLGGVLALLFSIFILLLVPLLHTSKLRSNIFRPLTQIFFWSLVTNAIILTWIGGQPVEQPFIMVGQIASVAYFSLFLFVIPITSWCENKFLSLN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSHC_ACIC1
Sequence: MHAWPAPKIPSLPGRNRLPSLFDTASRRLVTVGSQQGASMYVCGITPYDATHLGHAATYVAFDLLVRTWHDAGVTVRYAQNVTDVDDPLLERARQVDQPWEAIAARETAKFRADMAALRVVPPDRYVGVVESLPQIIGLIEVLRSRGLTYELDGDQYFATHAIPDFGAVSHLGRDDMIALFAARGGDPDRAGKKDPLDALLWRGKRPEEPSWPAPFGRGRPGWHVECAAIALTHLPLPLDVQGGGADLVFPHHDMTAAQAEAATGRRFARAYVHTGLVAYQGEKMSKSLGNLVFVSDLCAAGADPMAVRLALLDHHYRTEWEWTPRLLDEATDRLAEWRAAVRRPRGAPGDGLLAAVRDRLADDLDAPGAIALIDEWTTQDGDDPDAPTLVAAMADALLGVHL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.