PharMolix/UniProtQA huggingface dataset:
Protein: LONH_ECOLI
Sequence: MTITKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQFALEQLLHTRASSSFMLAKAPEESEYLNLIANAARTLQSDAGQLVGGHYEVSGHSIRLRHAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRTLLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQEMEPELSEQAIYSEFEDTLQIVDAESVTQWCRWVTFTARHNHLPAPGADAWPILIREAARYTGEQETLPLSPQWILRQCKEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDEILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAELGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISALADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVRHLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQQEGRHRFPWPLRWLNWFIPN
What are the official names of this protein?
Putative Lon protease homolog, ATP-dependent protease La homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
Protein: CLPX_SALTY
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RS19_XANOR
Sequence: MARSLKKGPFVDHHLAKKVESAAGSKKPIKTWSRRSMILPEMVGITIAVHNGKNHIPVLVNENMVGHKLGEFAVTRTFKGHGGDKKSSR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RS20_CAUVC
Sequence: MANNPGAKKAIRKIARRTEVNTARRSRVRTFLRKFEDAIAKGDVAVAKAAFVEAQSELMRAVSKGVVHPNTGSRKVSRLAARLKKLDKAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PURA_SYNR3
Sequence: MANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVDGQVLKLHLIPSGILYPDTTCLIGSGTVVDPKVLLGELAMLASNDIDASGLKVASTAHVTLPYHRLLDQAMEQQRGNQRIGTTGRGIGPTYSDKAERSGLRMIDLLDEQLLRERLQGPIAAKNLQLQKLYGLEPLDAEEVIAEYADYGRRLSSHVVDCTRAIHDAARARKNILFEGAQGTLLDLDHGTYPYVTSSNPVAGGACIGAGVGPTLIDRVIGVAKAYTTRVGEGPFPTELEGSLSDHLCDRGGEYGTTTGRRRRCGWFDGVIGRYAVEVNGLDCLAITKLDVLDELDEIQVCVAYELDGQRVNHFPSSASEFARCQPVFETLPGWQTSTADCRSLDDLPEKAMSYLRFLADLMEVPIAIVSLGASRDQTIVVEDPIHGPKRALLSA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_PROM4
Sequence: MAVPKKKTSKGKRNQRHSIWKAKAGIAAQKALSLGKSVLTGRSQGFVYPIDEQEEAEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RSMH_GLUOX
Sequence: MNAITLVHSGHVPVMLHEVLEALSPRAGGRYLDGTFGGGGYARAILNAADCTLDAIDRDPAAIERGNAMAVQANGRLRMHQGTFGDMEALAGAEGPFDGIVLDLGVSSFQIDQAERGFSFRNDGPLDMRMGSDGPSAADLVNTCKEAELADILYRYGEEKLSRRIARAIVAARAEAPITTTGQLAHIIRCCVPRDRANIDPATRSFQGLRIAVNDELGELERALEAAPRLLAPGGIFVVVTFHSLEDRLAKRAMAVLAGRTGNPSRYEPAPLRQEAPAFSLLYSRPLSATDEESRENPRARSARLRALVCNPAPKMPVSGMPS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U6_HHV6Z
Sequence: MPNLAAAVPCRPFVNLAQETGTTNLLVAGSRPTNTGVRNFVINLTVSESSSSRRTANRILLRSFTSLL
What are the official names of this protein?
Uncharacterized protein U6.
Protein: IHFA_SALPC
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKEE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ILVC_PROMA
Sequence: MAKLFYDSDADLQLLSQKTVAIIGYGSQGHAHALNLKDSGIDVVVGLYEGSRSASKASSDGLEVMSVADASAKADWIMILVPDEFQRDIYAKEVAPHLKPGKILSFAHGFNIRFGLIEPPSFVDVVMIAPKGPGHTVRWEFQNGQGVPALFAIEQDASGQARSLAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLCGGLSALVKAGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLTAMRDSISNTAEYGDYVSGPRLINADTKKEMKKILADIQDGTFAKNFVAECEAGKPEMKRIREEDSLLPIEKVGKGLRAMFSWLKTD
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: VL96_IRV1
Sequence: MCDIDLKTCEKSSKYKKKDIVDLGKKCGVDPYLPNGREKTRQVICTEIVNQYSTNPPSSSSESDDDEDMGKQDQDPICGISEKECNKLDNVNLLALGEYCGVDIYTPEGNLKTSKTICKSVSLKQSSPKAQKSPNKNDLINMDPANLKKLAKKLDIDWKKKDIKELQYLIAKKLNSIKSVSPSRSPSPRRSRSPSPNIQNMKKKELKALAKALGASDKKLDKMDKNQLIEYILSRKKSPSPVRKSRSPSLRQRSRSPGRSRSNSPVRPKYRAADLLGKKVVELKELAKMEGLKKWKDKTPSKMLKQDLVDFLLHVGGGGQLPKTPSPVKPSASPKTRAELALLKVPELKAMALSYGLKNFKDKTPSQLRKNDFIDFIILSTQKSQSPPPSIRSKPRSSSPKYKTKDLVTTDESDGEIVVKKITRKPKSPRRSPPASVRRSRTPSVPKSPSARPRSKSPSVRAEITDDEGETPPSSVRPKSPSVRPKSPSVRPRSKSPSVRPKSPSARPRSKSPSVRSKSPSVRPKSPSVRPKSPSVRPRSKSPSVRPKSPSVRPPPPDPSNSPSITVDPSVTPPSSVKIKKRPELPEYKGGNADRDLEILARRRGYKVIPVKGDGNCLFRAVGKSLRLNQNIKYSHEDLRAQVVTYLTSHKEFLEPYLEYVTESGDTTPQEYAKNVERYIKNISKPGTWGDFICLRVLSEILKVKFNLLILNTRNFQVISNNDTFKPLIPLGFIDDYHYTALTPLYAEPIAVLENETPTPSIAPSIRPPPSIIPSIAPSVRPSIAPSVRPSIVPATPSIVPSLKPSVVPKLTPSIAPKIPPPVFGPVKPLSSTRELLEEADKVHPYVREDISQLARAEEQILVSLGM
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation (By similarity).  May be involved in TIV genomic DNA packaging in a manner related to the Gag polyproteins of the mammalian viruses.
What are the official names of this protein?
Putative ubiquitin thioesterase L96.
Protein: GSDMC_RAT
Sequence: MLYTFDQVSKDVVKKLQGKDLRPVRCLSDATKFRQFDILQKTPQSLFFKSEDTPVGYSLLQILEPNFPVPETEVSAPMPLKHITSQKWKADVDVKATIADGGASAEFVQSCGYDIEVQSRSIPDSKLESLQNRQGPWGKLLDKKLSFVTDCQMGRNNLYVVTEVFEVTKDTVVQGSSSIDLSGKALVSQLVKGEAQGQWQRETTDLVPIPKGAVLAYKKKQLVIENNTCAILLSANAKKKTFPGIFNFGMSSRSQTMEIVNSSWIDYIPPIGRIEEPVHLDFKYLEKEVFLRKEQLAMLSKDVQDVVFSNLLPMLSDSDVLFDLINMLELDQLGHMDGPAGLILDELRKNSSTPWIDLKGLILYLLQALMVLSDTQLDLLAQSMEMRILLQQRELVRSILEPNFKYPWNIPFTLQPQLLAPLQGEGLAITYELLKGCGLKMEPNSPRSTWDLEAKMPLSALYGILSCLQQLVEA
What is the function of this protein?
Pore-forming protein that causes membrane permeabilization and pyroptosis (By similarity).  Released upon cleavage and binds to membrane inner leaflet lipids.  Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis (By similarity).  The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown (By similarity).
What are the official names of this protein?
Gasdermin-C.
What is the protein family that this protein belongs to?
Belongs to the gasdermin family.
What are the subcellular locations of this protein?
[Gasdermin-C]: Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Gasdermin-C, N-terminal]: Cell membrane; Multi-pass membrane protein.
Protein: SYP_BRUSU
Sequence: MRLSRYFLPILKENPKEAEIVSHRLMLRSGMIRQQSAGIYSWLPIGLKVLNKVCTIIREEQNRAGANEILMPTIQSADLWRESGRYGAYGKEMLRIQDRQEREMLFGPTNEEMVTDIFRSYVRSYKDLPLNLYHIQWKFRDEVRPRFGVMRSREFLMKDAYSFDLDYEGAKMAYYRMFVSYLRTFARVGLQAIPMRADTGPIGGDLSHEFIILAETGESQVYCDRAYLDLAVPGADTDFRNDAQLTDIVTRWTTPYAATDEMHDEADWAKVKPESQVSARGIEVGHIFHFGTKYSEPMGAKVQGPDGKEHLVSMGSYGIGPSRLVAAAIEASHDDAGIIWPKAIAPFGAGIVNMKPGDEGCDGVSEKLYEALTNAGVDPLLDDKDERPGAKFATMDLIGLPTQVIVGPRGVAAGEVEVKDRKMGERQSLGIEAAINMLTAQA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_SHEWM
Sequence: MSKDNLHRYLFENADVRGELVQLEQSYQEVLSAHNYPAPIQNLLGQLLAATSLLTATLKFNGDISVQLQGDGPVSLAVINGNNLQQLRGVARFKGELSSDGDLQQLFGKGHMVITLTPTEGERYQGVVALDKPTLAGCLEEYFAQSEQLPTSITLFANGKQAAGMLLQVLPTEGDHNAEFEHLEQLTATVKAEELFELEAEEVLHRLYHQEEVRLFEPVAVTFSCTCSRERSASAIRTVSREEIESILAEQGKIEMGCEYCNTNYSFDSIDVAAIFSNTQAPETKQ
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECDF_ASPRU
Sequence: MFLHILCLLAGQALADDYRPVFHFVPEKNWMNEPNGLIKIGSTWHLFYQHNPTANVWGNLNWGHATSSDLVHWTHEPLAITSENGIEAFTGTSYYDAENTSGLGTSDNPPYLAWYTGYFPSNGTQDQRLAFSIDAGETWTKFEGNPVISAAQEAPHDATGGLETRDPKVFFHADSGKWIMVLAHGGQNKMSFWTSVDAKRWSWASDLTSTQVPGLPSAVKGWEVPDMFEVPVHGTDKTTWVLIFTPAEGSPAGGNGVLALTGSFDGTVFHPNPVNVSTLWLDYGRDFDGALSWENLPDSDGHRILAAISNSYGANPPTNTWKGMLSFPRTLSLHQSQTGQYFLQQPVSNLDTVSTPLVSVKNQTIAPGQVLLSSVRGTALDIRIAFSANAGTVLSLAVRKAGSQETVIQYRQSDATLSVDRTTSGLTSYDPAAGGVHTAPLRPDASGVVQIRALVDTCSVEVFGGQGEVVISDLIFPDETSDGLALQVIGGTAVLRSLEKFPRLGAVL
What are the official names of this protein?
Putative glycosyl hydrolase ecdF.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: CYSJ_THIRO
Sequence: MVLSQLNGLTSPLDERHVHALQIALKGMTPTQLAWVSGYLAGIGGGPLRMPTEPKAVERITILFGSQTGNAKAVAEQLGARASEQGMDARVISMGDFNPRKLSKEQWVLIVVSTHGEGEPPENAYALHAFIQDQGAGRLEQLPFAVLGLGDSSYEHFCRTAVDFDRRLAELGAQRILPLQCCALDYRSDTERWSSDALNRLSALAPRKASNVVAMPTLRSHQDLRSHQEQSRNRARPYDKDNPYTATLLENRRITTLDAVSDVRHLALAIEPDAMHYRPGDALGVWVENDPSLADTILAGVGIDGAARIELGDEELDLRHALIERLELTQLHPTTVRGWSRASGRTGAEDAGERLEREEQTRIYLAGNDAFRLPDAGDTPLIMIGAGTGVAPYRAFLQQRAANGHPGRNWLIFGNRHFHRDFLYQLDWQAHRKAGRLDRVSLAFSRDGAEKPYVQQRLREEGKEILRWLDAGAHLYVCGATAMGQAVDHALVEIFTIEAGLDPDCASLRRYPARECYATDDL
What is the function of this protein?
Catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavo-protein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (By similarity).
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SIR-FP.
Protein: YH21D_YEAST
Sequence: MEDHTLVAIVVFFGNGEPFHVSLSVEMVFVLLLSSTRIHEVVVLICYKLQHATWSWGNMSKNFSLKPDISLSFLLDIISINDICIYGCIALTVVFIL
What are the official names of this protein?
Uncharacterized protein YHR214C-D.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PNP_PSECP
Sequence: MEGPEIQFSEAVIDNGRFGKRVIRFETGRLAKQAAGAAMVYIDEDTALLSATTAGKHPREGFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTEAILACRLMDRPLRPAFVKGLRNEVQIVVTVLAINPDELYDVVAINASSMSTQLSGLPFSGPIGGVRVALVADENGSQWVAFPKHSQLENSVFNMVVAGRVAGDDVAIMMVEAEATDNSWNLIKEQGATAPTEEVVSEGLEAAKPFIKALCDAQADLAARAAKPTVEFPVFLDYQDDVYAAVEAAAADKLAAVFQIADKQERDTASDALKDEVTSSLAGQFEGREKELSAAFRSVTKHVVRQRILKDQIRIDGRGLTDIRQLTAEVEVLPRVHGSAIFERGETQIMGVTTLNMLKMEQQIDSLSPVTRKRYMHNYNFPPYSTGETGRVGSPKRREIGHGALAERALVPVLPSREEFPYAIRQVSEALGSNGSTSMGSVCASTLSMLNAGVPLKAAVAGIAMGLVSDQVDGQTRYAALTDILGAEDAFGDMDFKVAGTSEFVTAIQLDTKLDGIPASVLAAALKQAREARLHILEVINSAIDTPDELSEFAPRVIAVKIPVDKIGEVIGPKGKMINQIQEDTGADISIEDDGTVYIGATNGPSADAARSAINAIANPQVPEIGERYLGTVVKTTTFGAFVSLTPGKDGLLHISELRKLANGKRVDNVDDVVSVGQKVQVEITKIDDRGKLSLSPVVAEEEGAEGAERAHATEPAEGAEI
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y338_SHESW
Sequence: MGIKDWPEGEGPRDKLLQKGAAYLSDAELLAVLLRNGLAGLNAVDLARSLISEFGGLRNLLCAPKNQVCRLPGVGPVKYAQLQAAAELARRVAQENLQRGQVLTNPDLTRDYLMRQLTDRSYEVFAILLLDSQHRVIQFVELFRGTIDSASVYPREVVSLVLEKKAAAVIVCHNHPSGIAEPSQADRRITERLKNALATIDVSLLDHMVVGDREIVSFAERGWIN
What are the official names of this protein?
UPF0758 protein Sputw3181_0338.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: FABV_BURP0
Sequence: MIIKPRVRGFICVTTHPAGCAASVREQIAYVARRGPIERGPKKVLVIGASTGYGLAARIAAAFGAGAATLGVFFERAPADAKPGTAGWYNSAAFHDEAAARGLQATSVNGDAFSDEIKHKTIDAIRRDLGQVDLVVYSVAAPRRTHPKTGVTHQSTLKPIGHAVRLRGIDTDNEAIKETLLQPATPDEIADTVAVMGGEDWRMWIDALDAAGVLADGAKTTAFTYLGEQVTHDIYWNGSIGEAKKDLDRTVLALRGKLAARGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKARGTHEGCIEQVDGLLRDSLYGAQPHVDAEGRLRADRLELDPAVQARVLELWDQVTDDNLYPLTDFAGYKAEFLRLFGFGIDGVDYDAPVEPNVRIPNLIE
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: ATPF_YERE8
Sequence: MNLNATILGQAIAFVLFVLFCMKYIWPPIMAAIEKRQKEIADGLSSAERAKKDLDLAQANATDQLKKAKAEAQVIIEQASKRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MIG18_CAEEL
Sequence: MTFTLRLLVLCTVYSYVISQCDDNGVIYTNGDKWIRNNHFLVTCRDGNIQTLKCVTDSGHLLEVGSKSYVENGYEYMCAREVTDNLNTNTCPTFADFSDDIFKDRFAICCISRRFKGCVDANGDIVKSGFFVIGNKSLKYCRIQANQLQARIEPKGCFNGTEKDDVNDEELHIKKYAVWREGDIEYRCGDDGVHIQRCFPPELKKKAIWAGTAWIQEDGQVKTCGKIN
What is the function of this protein?
Required for the directional control of distal tip cell migration during gonadogenesis, probably by recruiting fibulin fbl-1 to the gonad basement membrane.
What are the official names of this protein?
Abnormal cell migration protein 18.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Colocalizes with metalloprotease mig-17 to the gonad basement membrane.
Protein: SMF_ECOLI
Sequence: MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVNGVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCALEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDEVTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
What is the function of this protein?
Partially complements natural chromosomal DNA transformation defect of an H. influenzae dprA disruption mutant (PubMed:16978360).  May help load RecA onto ssDNA (By similarity).
What are the official names of this protein?
Protein Smf.
What is the protein family that this protein belongs to?
Belongs to the DprA/Smf family.
Protein: MSRP_CAMJE
Sequence: MLITPEKLYKQRRNFLKLGAGALISSSVLASKLSALNFTSDTNPNKLEISDEELATNYVNFYEFSTDKRKAVSLAQNFNTQNWKIDISGEIEKPLTLSMEDILKFPLEERIYRFRCVETWSMVVPWVGFELRRLIEMAKPTSEAKFVKFTTLLDKSQFPDQDALFPTIDYPYVEGLRMDEAMHPLTLLAVGMYKKALKPQNGAPIRLVVPWKYGFKSIKSIVKIEFTKEQPKSTWESYAPSEYGFYANVNPNVSHPRWSQANERALGDFFTKPTLMFNGYEKEVASLYKNMDLKVNF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: EZRA_STRA1
Sequence: MSSGIILLLVAIVLLVIIAYVVGVVIRKRNDTLIANLETRKQELVDLPVQEEIEQVKLLHLIGQSQSTFREWNQKWTDLSTNSFKDIDFHLVEAENLNDSFNFVRAKHEIDNVDSQLTIIEEDIVSIREALEVLKEQEEKNSARVTHALDLYETLQKSISEKEDNYGTTMPEIEKQLKNIEAEFSHFVTLNSTGDPIEASEVLNKAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKDIEQRFQEVREAIRSNSDGLVSLDLDRARDENEHIQEKIDKLYDIFEREIAAYKVAHKDSKIIPQFLAHAKSNNEQLGHEIKRLSAKYILNENESLSLRSFTNDLEEIETKVLPSVENFGQEASPYTHLQILFERTLKTLTTVEENQMEVFEAVKTIESVETRARQNMDKYVNKLHMIKRFMEKRNLPGIPQDFLSTFFTTSSQIEALINELSRGRIDIEAVSRLNDVTTNAIANLEQATYLVVQDATLTEQLLQYSNRYRSFEQNVQKSFEQALYLFEVEHNYKASFDEISYALETVEPGVTDRFVTSYEKTQERIRF
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: DPH3_SCHPO
Sequence: MSFYDEIELEDFTFDAGTNLYTFPCPCGDRFEISLEDLQLGEDVARCPSCSLIVRVIYDEDEFMEVDNDASTAPIIIAA
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase, predominantly cbr1.  Acts as an electron donor to reduce the Fe-S cluster in dph1-dph2 keeping the [4Fe-4S] clusters in the active and reduced state.  Restores iron to dph1-dph2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM.  Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex.  The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
What are the official names of this protein?
Diphthamide biosynthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the DPH3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IF2_JANMA
Sequence: MASNNVAQFATELKMPADVLLTQLRDAGVEKSSTSDELSKADKDKLLDHLRRAHGVAPDGEKKKITLTRKETTEIKQADATGKSRTIQVEVRKKRTFVKRDESTPEEAPVKAAAPVIDEAEIERRAEEARRQAELIARQEADLREKQERLAKLEAEKEAQAKALKQAEQAEAEAQKADAAKPVEAKADESAQEEKKRVAAEESKKKAAQLAKDAAKEASEKAVATEAARKAVADEVAQIKAMMNAPRRAIKAPEPAAPVAAKPAEGTLHKPADKKAGEKKDEKKPAVTADKKSIKSANVSSTWQDDAKKRGAGIKTRGNTGGGRDGWRAGPKGRRPSHHDDRESNFQAPTEAVVKDVHVPETITVAELAHKMSVKASEVIKHLMKLGQMCTINQVLDQETAMILVEEMGHTAHAAKLDDPEALLEQGEEHADIEALPRAPVVTVMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAAGVPLVVAINKIDKPGANMDRVKQELIAEQVVPEEYGGDSPFVPVSAKTGEGIDALLEQVLLQAEVLELKAPVDAPARGLVVEAKLDKGRGPVATILVQSGTLKRGDVVLAGSAYGRVRAMLDENGKSITEAGPSIPVEIQGLTEVPNAGEEVMVMADERKAREIGLFRQGKFRDVKLAKQQAAKLENMFENMGEGEVKNLPMIIKTDVQGSQEALVGSLQKLSTSEVRVQVVHAAVGGISESDVNLAVASKAVIIGFNTRADASARKLAEANGVDIRYYNIIYDAVDEIKAAMSGMLAPEKREQALGLVEIRQVILVSKVGAIAGCYVLEGVAKRGSSVRLLRDNVVVWTGELDSLKRFKDDVKEVKAGFECGLTLKNFNDIKEGDQLEVFEVQEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_MOOTA
Sequence: MTTISDIYAREILDSRGNPTVEVEVFLESGGWGRAAVPSGASTGAYEAVELRDKDPKRYGGKGVLDAVNNINAIIAPELVGSDALDQREIDRQLIEMDGTPNKGKLGANAILGVSLAVAKAAADALGLPLYRYLGGVNAHTLPVPMMNILNGGKHADNNVDIQEFMVMPAGASDFASALRMGAEVFHSLKAVLQSKGLNTAVGDEGGFAPNLRSNVEAIEVLLEAIAKAGYEPGKDCFIALDPASTELYKDGKYVFAGEGVTRTSDEMVEFWASLVDKYPIISIEDGLAEDDWEGWQNLTKRLGHKVQLVGDDLFVTNTERLSRGIEMGAANAILIKVNQIGTLTETLEAIEMAKKAGYTAVVSHRSGETEDTTIADIVVAVNAGQIKTGAPSRTERVAKYNQLLRIEEELDAAALYPGLKAFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.