PharMolix/UniProtQA huggingface dataset:
Protein: Y3195_ARATH
Sequence: MTSLSVNDRKDFVDGQMKYWRQIAESDGFDIDDVPVPRGTRAGLWSVDCKHPRFRLRACLPKIYAMVGLHRYNLLRGTNFEHLELLKYNESMNCVCSYYITSVAVDLSSQLQKTFQIRVDEKSFGDLDLTVSVARPNDEEKVTTEKRFIHHFHCEAAADDFYKGALPDWPSVGDLNNQKRFYMVKKCELQSNDWIRLYLELAVGVRYQQTSESDLSKLQVLKVAIETKEEDVQPPNRRLKSKSLHVYITFKGLAKAPIGDEIGEHVERKAIVRRVIDERSGHLTLLGGFSNAKNDLNQSSDDEQPFGKRRRI
What are the official names of this protein?
UPF0725 protein At3g19520.
What is the protein family that this protein belongs to?
Belongs to the UPF0725 (EMB2204) family.
Protein: CP27A_HUMAN
Sequence: MAALGCARLRWALRGAGRGLCPHGARAKAAIPAALPSDKATGAPGAGPGVRRRQRSLEEIPRLGQLRFFFQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAPLLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQRQC
What is the function of this protein?
Cytochrome P450 monooxygenase that catalyzes regio- and stereospecific hydroxylation of cholesterol and its derivatives.  Hydroxylates (with R stereochemistry) the terminal methyl group of cholesterol side-chain in a three step reaction to yield at first a C26 alcohol, then a C26 aldehyde and finally a C26 acid (PubMed:9660774, PubMed:12077124, PubMed:21411718, PubMed:28190002).  Regulates cholesterol homeostasis by catalyzing the conversion of excess cholesterol to bile acids via both the 'neutral' (classic) and the 'acid' (alternative) pathways (PubMed:9660774, PubMed:1708392, PubMed:11412116, PubMed:2019602, PubMed:7915755, PubMed:9186905, PubMed:9790667).  May also regulate cholesterol homeostasis via generation of active oxysterols, which act as ligands for NR1H2 and NR1H3 nuclear receptors, modulating the transcription of genes involved in lipid metabolism (PubMed:9660774, PubMed:12077124).  Plays a role in cholestanol metabolism in the cerebellum.  Similarly to cholesterol, hydroxylates cholestanol and may facilitate sterol diffusion through the blood-brain barrier to the systemic circulation for further degradation (PubMed:28190002).  Also hydroxylates retinal 7-ketocholesterol, a noxious oxysterol with pro-inflammatory and pro-apoptotic effects, and may play a role in its elimination from the retinal pigment epithelium (PubMed:21411718).  May play a redundant role in vitamin D biosynthesis.  Catalyzes 25-hydroxylation of vitamin D3 that is required for its conversion to a functionally active form (PubMed:15465040).
What are the official names of this protein?
Sterol 26-hydroxylase, mitochondrial, 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase, Cytochrome P-450C27/25, Cytochrome P450 27, Sterol 27-hydroxylase, Vitamin D(3) 25-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Post-translationally targeted to mitochondria. All three of the receptor proteins in the TOM complex, TOMM70, TOMM20 and TOMM22 are required for the translocation across the mitochondrial outer membrane. After translocation into the matrix, associates with the inner membrane as a membrane extrinsic protein.
Protein: KCY_GEOKA
Sequence: MKRRISIAIDGPAAAGKSTVAKRIAERLSYVYIDTGAMYRALTYRALACGVDIHDEQALLSLLRDTSIELKPSPHGQIVLVNGDDVTDIIRGEAVTNAVSLVAKHPLVREEMVARQRALAEGGGVVMDGRDIGTHVLPNAEVKIFLKASVEERARRRHEENLARGFPSDLEKLKEEIARRDRLDSERETAPLRKAPDAVEIDTTSLSVEEVVERIMEIVNERIG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT1_NEOLU
Sequence: SPCTCSTCNCAGACNSCSCTSCSH
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 8 family.
Protein: NFUA_SALEP
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: TRHO_CHLTR
Sequence: MEKNYYALAYYYFGPVSNPHEEIALHKQLFKTMDVSCRIYISEEGINGQFSGYQPDAERYMAWLKQRPDFASIKFKIHHIEENIFPRVTVKYRKELVALGCSVDTTKQGKHISPEEWHEKLQENRCLVLDVRNNYEWKIGHFENAVLPDIETFREFPDYADRLAKEHDPAKTPVMMYCTGGIRCELYSALLLEKGFKEVYQLDGGVIAYGLKMGTGKWRGKLFVFDDRMAMPIDEADPNVSPIARCSLCNTDSDTYYNCANTDCNNLFICCESCIATHKGCCSEECSQAPRIRAFSAERGNKPFRRKHLCPTIEQSCCLKEQENQPA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RHAA_CLOB8
Sequence: MNVKEKYELAKKEYEKWGIDVDKVLDELNKVKISIHCWQGDDVKGFEVVQNELSGGIQCNGNYPGAARNAEELRKDLDKALSLIPGKHKVNLHAIYLETNGEFVDRDEIKPEHFANWVKWAKENGLGLDFNPTIFSHPKSADGLTLSHPDKEIRDFWIRHSIASRKIGEYFGKELGQTCLTNIWIPDGYKDIPSDRLGPRRRLKESLDEIFKVQIDKKYNLDCVESKVFGIGAEAYTVGSNEFYLNYAAKNNIMSLMDTGHYHPTEVVSDKLSAMLLFDEKVALHVSRPVRWDSDHVVVYDDELKEIAKEIVRNDALDRVIIGLDFFDASINRIAAWTIGSRNMIKALLNAMLTPNDKLRELQEEGNFTERLALMEEFKTYPMGDIWNYYCEKNNVPVGESWIKEVKEYEKDVLSKRN
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_RALPJ
Sequence: MAIRQATTPQHDAGTVLERKEQALKPPAMYKVLLLNDDYTPMEFVVMILQQYFSKDRETATQIMLTVHREGKGVCGLYTRDIAATKVELVSTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: ACBD7_MOUSE
Sequence: MSLQADFDQAAQDVRKLKSRPEDEELKELYGLYKQSVIGDINIACPAMLDLKGKAKWEAWNLQKGLSKEDAMCAYISKARELIEKYGI
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters.
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the ACBD7 family.
Protein: AURF_CALAK
Sequence: MCRFVDAIKSLLDESDITTLVALANRLSPFRVDYRRVVVGDALSVKPILVLEHEQPPCDGAWRSAAHINLGLGAAQQQHHPVPTRAVHGAAVGGVQCDGLASPPVSNNVMSDGTVDGDDDDLGYDQDTLYNQGTDYENEGGAVGQDGLPAPDAGLFQECMFSHRSASTPRAGGHGESYCQEVAQSSHAITCRELLERCILPNFEINHLENCESSTSGGIHHCLPDEHSGMTGLARNTPSASPVENSITVELDGALEIATDVRTGKFNTLRAAKRHRRNTSSLRLSSHDAGCVGDARSSAGVVKSPARRSTAVSDAALRKVKYAARTCIRADYFQFLEANLPRWVRDGIWGKEWSPNQTANVDGYENLQKAYWHVCRLDRQMRDDAIRSRMAMVLLHLEYENTCLSWKTCAHSGKKPVTKVGRGNISSLIDNIIENTHPEWRTADPGERSELRAKFHDRKRYGKRWWMLVKPLGSSILMLCSSKFAGMIKNTTVTAAMINEIKLAIQRSETGLMSLLSLANPIAESLFLDQGYDGHNAEQVLKALRAARLEVAPGEGVA
What is the function of this protein?
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of aurovertins, fungal polyketides that exhibit potent inhibition of adenosine triphosphate synthase (PubMed:26340065).
What are the official names of this protein?
Aurovertin biosynthesis cluster transcription factor aurF, Aurovertin biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDM34_YEAS6
Sequence: MSFRFNEAVFGDNSFNERVREKLSTALNSPSKKKLDILKSGIKVQKVDFPTIPQLEILDLDIITQPKSLAKGICKISCKDAMLRIQTVIESNLLLINEQDTPSFTMPQLINNGSFTIPITMTFSSIELEAITNIFVKNPGIGISFNDVDLDFKFDCSVKILQSTIERRLKESMHVVFKDVLPSLIFNTSQNWFTNRGESTSTIPGKREHHHQQTTMSRNVILDGSDFQELSPINMLRLSSIVSSRSTLSLHSTVMNSLSAIPGCLERQNLYRFISRMPSLNNYYSSQSFPQPKSSTVSSKQLVKPFYCSHNLLPKTVLDSSQYDLATITKIQSRLFDRSNSNDDNAKPRRRKIKCKKTRTPSNLQSQGEQAVDDSTAIETVTSTPVQTPIPELEEQSPPYLKTTVSIRDKYVIPEKISLNLDSKKDTSKKKPFYFIGLNSQEPSNNWKWGMEDSPPPYH
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34, Mitochondrial outer membrane protein MMM2.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: SMP09_NAUMA
Sequence: SFDSSVLTK
What are the official names of this protein?
Uncharacterized protein SMPP9.
Protein: HMDH_CANAL
Sequence: MLSFLTEVTGAIAQTSARRPIQFMVVPALLASIAYLSIIDDYIPEHIKSSSGSSGISYYHPYTSSHYKSQPDLDKWTAIDKEHINDDIYTQANQISVIPLRFRRFQDVVPNVPNAIHISDNEQILIVPTDQIENSLDQLQEITNNGITWKARNNDKLAKYYDYIRYGLNKVQDAIQHAENFDILLIFVAYLGMWYALIKVFVDMRKIGSKFWLAFSTLTSSTFAFLLALLVSNKFLHTKVSLLSLSEGIPFLVSVIGFKHKVSIATIVANSSTASPEDVPHVVGKAVSSHCLSMLRDHLVVIGGLLSCAIYAHHLTGLRNFCILSSLILSFDLILVYTFFSAILGLKVEINRARRTEDLQNALEEEGISSLVAARVAEQSATIEHPNEHNFFKSNNSSIAYFKVIMSLGFFAFHAFWLGSSWLYSTTDGGESFSRFSFLSNIPTLSQDISQQIPIGRKGTVVTILPTIFFMPSGFMVQLEDFIYLVLSKFSSAIRDSIISKFLVFGFALSIVTNVYFLNAARYQVSATHKLIEKEISRPQDSSVTATTTTTATGTTSSGAATSKTIGNNKGLKSVQEIPDNEDESSDEELEIKAPVKVLPLEECVKVLKEGKVKTLSNDEVSSLVVGGKLPLYALEKQLADNKRAVIVRRKAIAKLANAPVLDTNRLPYAHYDYDRVFGACCENVIGYMPLPVGVAGPLIIDEKPYHIPMATTEGCLVASTMRGCKAINAGGGVETVLTRDGMTRGPCVRFPTLKRAGAAKLWIDSEQGQATIKKAFNSTSRFARLQHIQTALAGTSLFIRFRTTTGDAMGMNMISKGVEYSLKYMVEECGWDDMEIVSVSGNYCTDKKPAAINWIEGRGKSIVAAARIPADVVTKVLKSDVDALVELNISKNLVGSAMAGSVGGFNAHAANLVTAVYLACGQDPAQNVESSNCITLMEKDKETGDLNVSVSMPSIEVGTIGGGTILEPQGAMLDLLGVRGPHPTNPGANAQQLAKIVASAVLAAELSLCSALAAGHLVQSHMQHNRSKAPAAGATTTTTPAITDSKASNGSIASNGKDLKRLEEGSVTCIKS
What is the function of this protein?
HMG-CoA reductase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (By similarity).  HMG1 catalyzes the reduction of hydroxymethylglutaryl-CoA (HMG-CoA) to mevalonate (By similarity).  The first module starts with the action of the cytosolic acetyl-CoA acetyltransferase ERG10 that catalyzes the formation of acetoacetyl-CoA.  The hydroxymethylglutaryl-CoA synthase ERG13 then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.  The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase HMG1 finally reduces HMG-CoA to produce mevalonate (Probable).
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, HMG-CoA reductase 1.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RF1_DICT6
Sequence: MLQKLVLDKLEEIEKRFKEIENLLTKEEIISDLSRYQSLLKERAKIEEIVEKFSEYKKLLKEREDLEVMTKEEQDEDLRSLAEAELEEIEKKLEKIEFDLKALLLPKDPNDEKNIIMEIRAGTGGEEAALFAADLFRMYVGYAQKKGWKVEIVSSNPTGLGGYKEIIFIVEGKGAYSRLKFESGVHRVQRVPITESSGRIHTSTATVAVLPEMEEVDVEIDPKDLRIETFRSGGAGGQHVNKTESGVRITHIPSGIVVQCQDERSQHQNREKAMKVLRARLYEYYQREKENEIASQRRQQVGTGERSEKIRTYNFPQRRVTDHRINYSSFQLEEVLSGELDEFIDRLILAEKEEQIKKLFEEVGATS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_SHEPW
Sequence: MSDVTTAEFNEEGKYLRKVRSFVLREGRLTKGQAQAMEQQWPSMGLDYTPEAIDLVEVFGREADTVLEIGFGMGGSLVEMAKASPELNFIGIEVHKPGVGACLSVAAEAGVTNLRVYHHDALEVLENSIAEGSLARVQLFFPDPWHKKRHHKRRIVQAPFAELIRSKLKVGGVFHLATDWENYSEHMLEVMTAAPGYKNQSATGDVVERPEHRPLTKFEARGHRLGHGVWDLMFERV
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: 1107L_ASFM2
Sequence: MLVIILGVIGLLASSNLVSSSTSTRVGGHLPLTFDPPENELGYWYTYVESCRFCWDCEDGVCTSRVWGNNSTSIVENDYVKYCEVSRWGDQCRYDVEEHIYYTMNCSDPKPWNPYKIAKEGVEKG
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-7L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
Protein: YAN9_YEAST
Sequence: MEDHTLVAIVVFFGNGEPFHVSLSVEMVFVLLLSSTRIHEVVVLICYKLQHATWSWGNMSKNFSLKPDISLSFLLDIISINDICIYGCIALTVVFIL
What are the official names of this protein?
Putative uncharacterized protein YAR069C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CSPV_VIBCH
Sequence: MSTKMTGSVKWFNETKGFGFLTQDNGGNDVFVHFNSIQSEGFKTLAEGQRVSFIVEQGKKGPQASNVVAL
What are the official names of this protein?
Cold shock protein CspV.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODPA_ACHLA
Sequence: DQNGKVVNEKMEPKLPKETLLKMYKTAVLGRNADIKALQYQRQGRMLTYAPNMGQEAAQIGMAAAMEPQDWNSPMYRELNTLLYRGDKLENVFLYWYGNERGSIKPEGVKILPTNIIIGSQSNIAAGLAMASKIRKTNEVTAFTIGDGGTAHGEFYEGLNFAASFKAPVVAVIQNNQWAISTPVRKASNSETLAQKGVAFGIPYIQVDGNDMLAMYVASKEAMDRARKGDGPTLIEAFTYRMGPHTTSDDPCSIYRTKEEENEWAKKDQIARFKTYLINKGYWSEEEDKKLEEEVLAEINDTFKKVESYGANVELIEIFEHTYAEMTPQLKEQYEEHKKYLEGVK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha.
Protein: CCMK3_SYNY3
Sequence: MPQAVGVIQTLGFPSVLAAADAMLKGGRVTLVYYDLAERGNFVVAIRGPVSEVNLSMKMGLAAVNESVMGGEIVSHYIVPNPPENVLAVLPVEYTEKVARFRT
What is the function of this protein?
A probably minor shell protein component of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered.  This subunit probably does not form homohexamers.
What are the official names of this protein?
Carboxysome shell protein CcmK3, Carbon dioxide-concentrating mechanism protein CcmK3.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family. CcmK subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: MIAA_BIFA0
Sequence: MPSAGVERHDGARVISIVGPTASGKTGLGIAIARRLADRGERAEIVNADAYQMYRGMDIGTAKASDEERAAVRHHLLDVIEPSETMSVARFQQMARETIADLKSRGIRPILVGGSGLYARAAIDDISFPGTDPQIREHLEERERTEGATALFRELAVKDPQAAEHMDPRNPRRIIRALEVIEVTGKPYSATLPRYRYVIPSVQLGLDLDRADLDKRIDVRTRQMFDGGFVDEVARLRSHLGPTAARALGYQQVIDHLDGLVDLDDTMADIAQKTKRLARKQMGWFGRDPRIHWLSALNPALVDNAMAVIDHADAGDYDAIDMHAQEYVQHHLGDIRRPSGAGPV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PG33_MYCTO
Sequence: MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAEAASAAPLEGVLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIGNGGAGGSGAAGMPGGNGGAAGLFGNGGAGGAGGNVASGTAGFGGAGGAGGNGGLLFGAGGAGGVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNGGLLFGAGGVGGVGGDGVAFLGTAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSGGSALLWGDGGAGGAGGVGSTTGGAGGAGGNAGLLVGAGGAGGAGALGGGATGVGGAGGNGGTAGLLFGAGGAGGAGGFGFGGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAILVGNGGNGGNAGSGTPNGSAGTGGAGGLLGKNGMNGLP
What is the function of this protein?
Induces TNF-alpha release through human Toll-like receptor 2 (TLR2) signaling pathway, leading to macrophage apoptosis.
What are the official names of this protein?
PE-PGRS family protein PE_PGRS33.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell surface. Cell outer membrane. Note=Exported to the cell surface via the ESX-5 / type VII secretion system (T7SS).
Protein: SYH_GEOKA
Sequence: MAFQIPRGTQDVLPGDSEKWQYVEHIARSLCSRYGYQEIRTPIFEHTELFLRGVGDTTDIVQKEMYTFEDKGGRALTLRPEGTAPVVRAFVEHKLYGSPNQPLKLYYSGPMFRYERPEAGRFRQFVQFGVEALGSSDPAIDAEVMALAMHIYEALGLKRIRLVINSLGDLDSRRAHREALVRHFSNRIHELCPDCQTRLHTNPLRILDCKKDRDHELMATAPSILDYLNDESRAYFEKVKQYLTALGIPFVIDARLVRGLDYYNHTTFEIMSEAEGFGAAATLCGGGRYNGLVQEIGGPETPGIGFALSIERLLAALDAEGVELPVESGLDCYVVAVGERAKDEAVRLVYALRRSGLRVDQDYLGRKLKAQLKAADRLGASFVAIIGDEELERQEAAVKHMASGEQTNVPLGELAHFLHERIGKEE
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMDA_ORYSJ
Sequence: MVLEATMICIDNSEWMRNGDYSPSRFQAQADAVNLICGAKTQSNPENTVGVMTMAGKGVRVLVTPTSDLGKILACMHGLEVGAEANLAAAIQVAQLALKHRQNKRQQQRIIAFIGSPVKYDKKVLETIGKKLKKNNVALDIVDFGETDDDKPEKLEALISAVNSSDSSHIVHVPPGENALSDVLISTPIFTGEEGGSGFAASAAAAAATGAAGFEFDVDPNVDPELALALRLSMEEERARQEAIAKKAAEESSGAENKDHASSSNADSVMAEAEPASNAADDKKDQPKEDDDAQLLQQALAMSMEEGSSGAAAADAAMAEAAVDDQDLALALQMSVQDAGGSSQSDMSKVFEDRSFVTSILNSLPGVDPNDPSVKDLLASLHGQGEQEKKEDKSDKPEDEKK
What is the function of this protein?
Plays a role in maintaining the structural integrity of the 19S regulatory particle (RP), subcomplex of the 26S proteasome.  Plays a major role in both the direct and indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).  Binds and presumably selects ubiquitin-conjugates for destruction.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 4 homolog, 26S proteasome regulatory subunit RPN10, OsRPN10, 26S proteasome regulatory subunit S5a homolog, OsS5a.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5A family.
Protein: YNL5_YEAST
Sequence: MKANGLDNDPARTGMERTDIDSEHPEAQPLLNNNHRTLGAGSANGPAVNEGRDIESDGFIKDSLFQIRKGYRIFIHNSKWILNILILINTIWLVTTLISDFFFNINILFGFSNRYASFNDLTLIFISIIANSFNLWFNKLGLYSALDYSLNVTLCVLTLFNLALTYLIKYTRQRIGFVGTFTYLWTSFSFFIGAILDWYLLFYNNSINEPLEERRIDDANISTFNENHTNSTENRDRSQYGSGSPTPTHRSQLVQNKHTLTEWVSIGFRNTIKFLILIFFALFTLNTLLTTLDTYRLTHKLPITVQSPSYEAFHYVDAAKTYQLHITCYGDVFDQENNTDLSENKKQPIILFEHGGYDTGYLSATWIEELYHLDKIQRYCLYDRPGYGLSDSPPAPISIAMVAESLRYALIKDAKIKGPFTTVGYDLGGLFTRVFTAKNVDIVDSMMLVESWHEELLLKNYIQRLLPPGRGDGDDGDDGNGNDGDGRNHDKTWLPSEIERHNEFRLWWKGIWSSLGWRLQTSWLLAHHGSKERIYGRDMKYQGRFLRSKFLESVTSSILSYRDVTNNAESLQNVKTSIVSSKEMVKKSALWGDWQRDLTKISHKTQEWKIVEGGHEIYKYGLGKQQTQEVLLRLIGELGKLTED
What are the official names of this protein?
Uncharacterized vacuolar membrane protein YNL115C.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: EPSE_RALSL
Sequence: MQKTAPRPLPARISFLSASVLGLGAAVASRGAVFVSNILLAHSLTVHDFGLFSYAYVTALNLGLFLATGVSQAAGHVLPLIENPERKRTQLCAFIVLLMALIAVAAAALYLSSASISVAAFGSEQGSGALRMAAIVLIATAFTQALQSFQYAMHEHRSSATISIGAAVLLLTMLWAMGPIRQPALALTIFLAVNAGAAVSQLLVLARATPSQRGPWRTGREELRLAVKHALPSVLTTSMGAPVHWICLSMLAAMTDGAHQLALFSVAFQWYIAITFIPATLGNLALPFLARHAGATETTVRQRFRSALLFGGGLSLALGCASFLLAGEIFAWFYPAEYGSAASSMRSLSVAAALCGVSVLLQQRIAAAGKFWRNFAMAAVYSVIYVAASYLALRLGFGATSIGLAMSAAYCCLILFQTLTLQGDSGAAIRLGRSFS
What is the function of this protein?
Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor.  May play a role in export of EPS I or its intermediates across the membranes.
What are the official names of this protein?
EPS I polysaccharide export inner membrane protein EpsE.
What is the protein family that this protein belongs to?
To E.coli bicyclomycin resistance protein (BCR).
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL23_ONCVO
Sequence: MSKRGRGGTSGAKFRISLGLPVGAVMNCADNTGAKNLFVIAVYGIKGR
What are the official names of this protein?
60S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y3503_METJA
Sequence: MRDCKVQVGGFGEWIIKCDLELTFDEVMRGEIEELVEFIKSLESLLKSSSEDSFRKNVLNALISTLKTLPWTSRLEYADDEHNIIDVYPDDKNKKWIIKCNLCLFPDE
What are the official names of this protein?
Uncharacterized protein MJECL03.
Protein: EBFC1_ARATH
Sequence: MASTATNTDFFKTLLSPFSNGNAAQRSSRQNIVWLNRKQSGNNNRSLRVNGLFGGGKKDNKEDGQSKAGILGNMQNLYETVKKAQMVVQVEAVRVQKELAVAEFDGYCQGELVKVTLSGNQQPIRTDITDAAMELGSEKLSLLVTEAYKDAHSKSVLAMKERMSDLAQSLGMPPGLDGLK
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein At4g30620, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Plastid, chloroplast.