PharMolix/UniProtQA huggingface dataset:
Protein: VEMP_BCHK5
Sequence: MLPFVQEQIGAFIVNFFILSVVCAVTLVVCLAILTAIRLCVQCVSGCHTLVFLPAVHIYNTGRAAYVKFQESHPPYPPEDWV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: RS13_MANSM
Sequence: MARIAGINIPDHKHTVIALTAIYGIGKTRSQAICAAAGIAENVKISELSEEQIDKLRDEVGKFTVEGDLRREVTLNIKRLLDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RBFA_SALPK
Sequence: MAKEFGRPQRVAQEMQKEIALILQREIKDPRVGMMTTVSGVEMSRDLAYAKVFVTFLNDQDEAAVKNGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTNVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHG25_HUMAN
Sequence: MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 25, Rho-type GTPase-activating protein 25.
Protein: CRYAA_TRIIN
Sequence: MDVTIQHPWFKRALGPFYHNRLFDQFFGEGLFEYDLLPFQSLFRTVLDSGISEVRSDRDQFLILLDHFSPEDLTVKVLDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDKSALSCSLSADGMLTFCGPKVQSGMDASHSERAIPVSREEKASSAPNS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: PETD_CITSI
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACTVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPTGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALCLGIGATLPIEKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: T3RH_HAEIN
Sequence: MRSIKRRKKMANDKTLFDWVEDRKSTLEEMEQTDFFALPEFVERNLKYPFFEWQKSALENFLIFDRTSKLKDFPDIKNRPTHLLFNMATGAGKTMMMAALILYYFEKGYRHFLFFVNQNNIVDKTENNFTDPTHAKFLFTEKILQGDTVIPIRKVETFSPHSDGIEIKFTSIQKLYNDIHTEQENQTTLTDLHDLNLVMLGDEAHHLNAQTKGKKQGELDLEKEMNDRTSKAEIERKGWEHMVLELLLNKNGNPSENVLLEFTATLPENAEVQQKYADKIITKFGLKEFLQKGYTKEINLVSSTLGKKERVLHALLFAWYRHQIALKYGIANFKPVMLFRSKTIDESKADYLAFLNWVENVQAVDFSFLTTFLASLNDSDNANEQGKTRTEQALKFIQDNKFEFVHLADWVKQNYQKHNVIITNSETNKSKTEKTDSETEKLLNNLEAADNPIRAIFTVDRLTEGWDVLNLFDIVRLYEGQNGGGSNKKSGKSCRHRIRKAVNWSWRALFSICV
What is the function of this protein?
A type III restriction enzyme that recognizes 2 inversely oriented double-stranded sequences 5'-CGAAT-3' and cleaves 25-27 base pairs downstream.  After binding to one recognition site undergoes random one-dimensional diffusion along DNA until it collides with a stationary enzyme bound to the second DNA site, which is when DNA cleavage occurs.  DNA restriction requires both the Res and Mod subunits (By similarity).
What are the official names of this protein?
Probable type III restriction-modification enzyme HindVIP Res subunit, Probable type III restriction enzyme HindVIP.
What is the protein family that this protein belongs to?
Belongs to the type III restriction-modification system Res protein family.
Protein: SBT4_LOTJA
Sequence: MDYFLFIALTFLLTFHVHNAQGSELPTTTTESTETSSSKIYIIHVTGPEGKMLTESEDLESWYHSFLPPTLMSSEEQPRVIYSYKNVLRGFAASLTQEELSAVEKKNGFISAHPQRVLHRQTTHTPKFLGLQQDTGVWKESNFGKGVIIGVLDSGITPGHPSFSDVGIPPPPPKWKGRCDLNVTACNNKLIGARAFNLAAEAMNGKKAEAPIDEDGHGTHTASTAAGAFVNYAEVLGNAKGTAAGMAPHAHLAIYKVCFGEDCPESDILAALDAAVEDGVDVISISLGLSEPPPFFNDSTAIGAFAAMQKGIFVSCAAGNSGPFNSSIVNAAPWILTVGASTIDRRIVATAKLGNGQEFDGESVFQPSSFTPTLLPLAYAGKNGKEESAFCANGSLDDSAFRGKVVLCERGGGIARIAKGEEVKRAGGAAMILMNDETNAFSLSADVHALPATHVSYAAGIEIKAYINSTATPTATILFKGTVIGNSLAPAVASFSSRGPNLPSPGILKPDIIGPGVNILAAWPFPLSNSTDSKLTFNIESGTSMSCPHLSGIAALLKSSHPHWSPAAIKSAIMTSADTINLGNKLIVDETLQPTDLFATGSGHVNPSRANDPGLVYDIQPDDYIPYLCGLGYSETEVGIIAHRKIKCSASIPEGELNYPSFSVELGSSKTFTRTVTNVGEAHSSYDLIVAAPQGVDVKVQPYKLNFSEVNQKETYSVTFSRTGLGNKTQEYAQGFLKWVSTKHTVRSPISVKFI
What is the function of this protein?
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e. g.  Glomeromycota intraradices).
What are the official names of this protein?
Subtilisin-like protease 4, SbtM4, Subtilase 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Note=Accumulates in the intercellular spaces and the periarbuscular space (PAS) during arbuscular mycorrhizal (AM) symbiosis.
Protein: SODCP_PICAB
Sequence: MTKKAVVVLWGISQVEGVVNLLQE
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn], chloroplastic, SOD I.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UBL4A_DANRE
Sequence: MILTVKPLQGKECNVQVTENEKVSTVKELVSERLNIPASQQRLLYKGKALADEHRLSDYSIGPEAKLNLVVRPAGERSSGAVGTSSANNDKGGSGVWQLLSTVLAKHFSPADAAKVQEQLIKDYERSLRQLSLDDIERLASRLLHPETEVMDTSYMD
What is the function of this protein?
As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation.  The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane.  Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum.  The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome.  It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
What are the official names of this protein?
Ubiquitin-like protein 4A.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: PELO_METTP
Sequence: MRVIKRNLRGDEGEISLVAESLDDLWHLKHLVSPGDLVFATTQRKISGATDKLRPEKAERRTVRLGISVEAVEFHTYSNWLRIHGVIKSGVDIGSYHTLNIEAGSELSIIKRWRPDELQRIEEAVAESNRPRVVLALVEEGEATIGVLRQFGVQTVAEIRGGSGKGSGSSVRDDFLKEVADQIANSAGDDAYVVLAGPGFTKEDLRKVMEARYPDLLKRLTMDDASSTGRSGFQEVLRRGTVDRIVEASRISRETRLMDDLMKEIATDGRAAYGIREVREAANYGAIETLMIVDQLVRRGDVESLIRDVAAGRGRVVIFSTEFEPGERLEALGGVAALLRFRIPGAS
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MD2L2_RAT
Sequence: MTTLTRQDLNFGQVVADVLSEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSINSDSLLSHVEQLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKNS
What is the function of this protein?
Adapter protein able to interact with different proteins and involved in different biological processes.  Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis.  Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions.  Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs).  During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection.  Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres.  May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1.  Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle.  Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
What are the official names of this protein?
Mitotic spindle assembly checkpoint protein MAD2B, Mitotic arrest deficient 2-like protein 2, MAD2-like protein 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm.
Protein: Y1443_STRP7
Sequence: MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDSYKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK
What are the official names of this protein?
UPF0223 protein SP70585_1443.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: PIGA_ARATH
Sequence: MAEPPKLRVLMVSDFFFPNFGGVENHIYYLSQCLLKLGHKVVVMTHAYGNRSGVRYMTGGLKVYYVPWRPFVMQTTFPTVYGTLPIVRTILRREKITVVHGHQAFSTLCHEALMHARTMGYKVVFTDHSLYGFADVGSIHMNKVLQFSLADIDQAICVSHTSKENTVLRSGLSPAKVFMIPNAVDTAMFKPASVRPSTDIITIVVISRLVYRKGADLLVEVIPEVCRLYPNVRFVVGGDGPKHVRLEEMREKHSLQDRVEMLGAVPHSRVRSVLVTGHIFLNSSLTEAFCIAILEAASCGLLTVSTRVGGVPEVLPDDMVVLAEPDPDDMVRAIEKAISILPTINPEEMHNRMKKLYSWQDVAKRTEIVYDRALKCSNRSLLERLMRFLSCGAWAGKLFCMVMILDYLLWRLLQLLQPDEDIEEAPDICLCHHRGVEVSEGLRKKIK
What is the function of this protein?
Necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis (Probable).  Required for pollen germination and pollen tube growth (PubMed:14671020).
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, GlcNAc-PI synthesis protein, Phosphatidylinositol-glycan biosynthesis class A protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RUVB2_AEDAE
Sequence: MAELDKIEVRDITRIERIGAHSHIRGLGLDDVLEARAVSQGMVGQKDARRAAGLVVQIVREGKIAGRCILLAGEPSTGKTAIAVGMAQALGNETPFTSMSGSEIYSLEMNKTEALSQALRKSIGVRIKEETEIIEGEVVEIQIDRPASGTGQKVGKVTIKTTDMETNYDLGNKIIECFMKEKIQAGDVITIDKASGKVSKLGRSFTRARDYDATGAQTRFVQCPEGELQKRKEVVHTVTLHEIDVINSRTHGFLALFAGDTGEIKQEVRDQINSKVMEWREEGKAEINPGVLFIDEAHMLDIECFSFLNRALESDMAPVVIMATNRGITKIRGTNYRSPHGIPIDLLDRMIIIRTVPYSAKEIKEILKIRCEEEDCQINNEALMVLGRIATETSLRYAIQSITTASLVSKRRKAAEITVEDIRKVYSLFLDEKRSSKIMKEYQDEYLFYDDSLSQAEQAMEVETN
What is the function of this protein?
Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
RuvB-like helicase 2, Reptin.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SP5G_GEOTN
Sequence: MEVTDVRLRRVNTEGRMKAIASITLDNEFVVHDIRVIDGNNGLFVAMPSKRTPDGEFRDIAHPINSATRGKIQEAILAEYHRLGKLEEELEEAGAS
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: YUZK_BACSU
Sequence: MEKAMQLSHGIGYEEYGRRLETRMKVERQRELDYEKSKRISAGAY
What are the official names of this protein?
Uncharacterized protein YuzK.
Protein: KLH41_RAT
Sequence: MDSQRELAEELRLYQSTLLQDGLKDLLEEKKFIDCTLKAGDKSFPCHRLILSACSPYFREYFLSEIEEEKKKEMALDNVDPAILDLIIKYLYSASIDLNDGNVQDIFALSSRFQIPSVFTVCVSYLQKRLAPGNCLAILRLGLLLDCPRLAISAREFVSDRFVQICKEEDFMQLSPQELISVISNDSLNVEKEEVVFEAVMKWVRTDKENRAKNLSEVFDCIRFRLMAEKYFKDHVEKDDIIKSNPEVQKKIKVLKDAFAGKLPEPSKSAEKGGTGEVNGDVGDEDLLPGYLNDIPRHGMFVKDLILLVNDTAAVAYDPMENECYLTALAEQIPRNHSSIVTQQNQVYVVGGLYVDEENKDQPLQSYFFQLDNVSSEWVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKVYGHNVISHNGMIYCLGGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIAGGVTEDGLSASVEAFDLKTNKWEVMTEFPQERSSISLVSLAGSLYAIGGFAMIQLESKEFAPTEVNDIWKYEDDKKEWAGMLKEIRYASGASCLATRLNLFKLSKL
What is the function of this protein?
Involved in skeletal muscle development and differentiation.  Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils.  Required for pseudopod elongation in transformed cells.
What are the official names of this protein?
Kelch-like protein 41, Kel-like protein 23, Kelch repeat and BTB domain-containing protein 10, Kelch-related protein 1, Sarcosin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, pseudopodium. Cell projection, ruffle. Cytoplasm, myofibril, sarcomere, M line. Sarcoplasmic reticulum membrane. Endoplasmic reticulum membrane. Note=Predominantly cytoplasmic but can colocalize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia.
Protein: RS11_SYNP6
Sequence: MARPTKKSGPRKQKRNVPSGVAHIQSTFNNTIVSIADPAGEVISWASAGSSGFKGAKKGTPFAAQTAAEAAARRAIDQGMRQLEVMVSGPGSGRETAIRALQSAGLEITLIRDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: UDT1_ORYSJ
Sequence: MPRRARARGGGGGGGEEVKVEDDFIDSVLNFGGGGGGEEDGDDGEEEQQQQQAAAAAMGKEFKSKNLEAERRRRGRLNGNIFALRAVVPKITKMSKEATLSDAIEHIKNLQNEVLELQRQLGDSPGEAWEKQCSASCSESFVPTENAHYQGQVELISLGSCKYNLKIFWTKRAGLFTKVLEALCSYKVQVLSLNTISFYGYAESFFTIEVKGEQDVVMVELRSLLSSIVEVPSI
What is the function of this protein?
Transcription factor that plays a crucial role in tapetum development.  Required for male fertility and pollen differentiation within the developing anther.  Plays a major role in maintaining tapetum development, starting in early meiosis.  Required for pollen mother cell meiosis.  May regulate the anther-specific cysteine protease CP1 and lipid-transfer proteins C4 and C6 (PubMed:16141453).  Required for anther development.  Functions in parallel with GAMYB to regulate early anther development.  Functions upstream of the transcription factor TDR and may positively regulate its transcription (PubMed:20590996).
What are the official names of this protein?
Transcription factor UDT1, Basic helix-loop-helix protein 164, OsbHLH164, Protein UNDEVELOPED TAPETUM 1.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSA_STRCO
Sequence: MSTPFYVSPQQAMADRAEYARKGIARGRSLVVLQYADGIVFVGENPSRALHKFSEIYDRIGFAAAGKYNEYENLRIGGVRYADLRGYTYDRDDVTARGLANVYAQTLGTIFSSQAEKPYEVELVVAEVGDSPENDQIYRLPHDGSIVDEHGSVAVGGNAEQISGYLDQRHRDGMTLAEALKLAVQALSRDTNGTEREIPAERLEVAVLDRTRPQQRKFKRIVGGQLSRLLESGAASADGEAETEAETDSGSDEE
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.  The S. coelicolor proteasome is able to cleave oligopeptides after hydrophobic residues, but not after basic or acidic residues, thus displaying chymotrypsin-like activity but not trypsin-like activity.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_CERS1
Sequence: MAKVIGIDLGTTNSCVAIMDGAQPRVIENSEGARTTPSIVGFTDSERLVGQPAKRQAVTNPSNTVFAVKRLIGRRVGDAEVEKDKKLVPYSIVNGGNGDAWVEVRGEKYSPSQISAFILQKMKETAEAYLGETVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKKDTKTIAVYDLGGGTFDITILEIDDGLFEVKSTNGDTFLGGEDFDMRIVNYLADEFKKEHGVDLTLDKMALQRLKEAAEKAKIELSSSQQTEINQPFISMDRNTGQPLHMVMKLTRAKLESLVGDLIKKSLKPCEAALKDAGVSKSDIDEVVLVGGMTRMPRVVEEVTKFFGKEPHKGVNPDEVVALGAAIQAGVLQGDVKDVVLLDVTPLSLGIETLGGVFTRLIDRNTTIPTKKSQVFSTAEDNQNAVTIRVFQGEREMAADNKLLGQFNLEDIPPAPRGMPQIEVTFDIDANGIVSVSAKDKGTGKSQNITIQASGGLSDEDIEKMVRDAEANAEADKKRRELVETKNQGESLLHSTRKSIEEHGDKVDPSTVEAIELAMGALEEALKSEDAGKIKGGIQNLTEAAMRLGEAIYKASQAEGGATPDEEGPRSVDDDIVDADFEDLGENKRK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RNY_CLOP1
Sequence: MVVGILIGIIILGVVGFIQYTLIQKASKNRVESLEKEASLTLEEAKREAESTKKEAILEAKEEVHKLRADLDKETRDRRNEIQRFERRLIQREESLDKKGEMLEKREDSINKKSIEIQELEERVQNLYGEQRAELERISNLSSEDARTLLLDEVRREIKHESAMLIKELETKAKEEADKKSREIITTAIQRCAADHVSETTVHVVALPNDEMKGRIIGREGRNIRTLETLTGVDLIIDDTPEAVILSSFDPIRREVARIALEKLIVDGRIHPARIEEMVERAIKDVENDIKEEGEQATFETGVHGLHPEIIKLLGRLKYRTSYGQNVLKHSIEVSYLAGLMASELGLDVNLARRAGLLHDIGKGVDQEYEGPHAVIGGELAKKYHESPAVVNAIAAHHGDTEMQTLEAVLVQAADAISAARPGARRETLEAYIKRLEKLEEIATSYEGVEKSYAIQAGREIRIMVKPDQVDDAGAIEMARNIVKKIEEQLEYPGQIKINVIRETRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MAP2_MOUSE
Sequence: MAGVEQAASFGGHLNGDLDPDDREEGTSSTAEEAAKKKRRKKKKGKGAVSAVQQELDKESGALVDEVAKQLESQALEEKERDDDDEDGDGDADGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDILLTAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
What is the function of this protein?
Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR.  Plays a critical role in the regulation of protein synthesis.
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Initiation factor 2-associated 67 kDa glycoprotein, p67, p67eIF2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About 30% of expressed METAP2 associates with polysomes.
Protein: NADE_SALPC
Sequence: MTLQQEIIQALGAKPHINPEEEIRRSVDFLKAYLKTYPFLKSLVLGISGGQDSTLAGKLSQMAIAELREETGDNALQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTHGVVVGTDHAAEAITGFFTKYGDGGTDINPLHRLNKRQGKQLLAALGCPEHLYKKVPTADLEDDRPSLPDEAALGVTYDNIDDYLEGKTLDPAIAKTIEGWYVKTEHKRRLPITVFDDFWKR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: METAA_STRZT
Sequence: MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDYWEEFTQVLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQMDSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEILNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDRDTLAKEYFRDCDAGLAPHIPENYFKDDDVNQTPCLCWSSSAALFFSNWVNYAVYQETPFDWRKIEDDASAYGYL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.