PharMolix/UniProtQA huggingface dataset:
Protein: CLZ20_COCLU
Sequence: MVSTRGVLYYLLRPKELRPILQWKALHGLGHQRDEKNESPDVKACYQYLALTSRSFAAVCQQLDRELLMPICIFYLILRGLDTIEDDMTLSKEVKEPLLRNFYTTIYDQTWTFNDSGTDEKDRELLVHFDCVAREFHKIKDEYKIIITDITKQMGNGMADFVVSGDLTGIQKIKDYELYCHYVAGVVGDGLTRLFVEANVADPSLLKNPRLIESMGQFLQQTNIIRDVREDHDEVRHFWPKEVWSKYAQDFDHLVSPKPQDRKKALQCSSEMVLMALNRADDCLNYMAGVREQTVFNFVAIPQSMAIATLELCFQNPAIFDKNIKITKGATCQLMIDSTQDLQHVCQAFRRYARRIKKKNHPEDPHFHDINAACNKIDRFIDDRYPNLQDEQAKADTMYLAVLVLGVFGVVAAIL
What is the function of this protein?
Squalene synthase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS) (PubMed:28605916).  Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene (By similarity).  The presence of a gene encoding a squalene synthase supports the identification of the cluster as being responsible for SQS1 production and suggests a likely mechanism for self-resistance (Probable).
What are the official names of this protein?
Squalene synthase clz20, SQS clz20, SS clz20, Squalestatin S1 biosynthesis cluster protein clz20, Zaragozic acid A biosynthesis cluster protein 20.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS5_CAMJR
Sequence: MEKYNREEFEEVIVDIGRVTKVVKGGRRFRFTALVIVGNRKGLVGVGYGKAKEVPDAIRKAVDDAFKNIVEVKTKGSTIAHDVEVKYNASRILLKPASEGTGVIAGGSTRPIVELAGIKDILTKSLGSNNSANVVRATIKALTMLKG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RNP1_THEON
Sequence: MRRNGKEGKDRAPGRPQRKGQEVASRPWIFRGLDRNRVTAKNILWHELIGLKAKIIRASHPELVGIEGYVLDETRNTLTICGERVWVIPKDVVELEFEVGDKRIRINGRELIGRPEMRLKKRWRR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP1S1_BOVIN
Sequence: MRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes.  The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).
What are the official names of this protein?
AP-1 complex subunit sigma-1A, Adaptor protein complex AP-1 subunit sigma-1A, Adaptor-related protein complex 1 subunit sigma-1A, Clathrin assembly protein complex 1 sigma-1A small chain, Clathrin coat assembly protein AP19, Golgi adaptor HA1/AP1 adaptin sigma-1A subunit, HA1 19 kDa subunit, Sigma 1a subunit of AP-1 clathrin, Sigma-adaptin 1A, Sigma1A-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: EFG_LEPCP
Sequence: MARQTPIERYRNIGISAHIDAGKTTTTERILYYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMDRSLPEHRFNIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVVDQMKTRLRANPVPVVVPIGAEDSFTGVVDLLKMKAIIWDEASQGMKFSYEDIPAGLEGVAQEWREKMVEAAAEASEELMNKYLETGDLTEDEIKLALRTRTIACEIQPMLCGTAFKNKGVQRMLDAVIDYLPSPVDIPPVTGTDDDDQPISRRADDKEKFSALAFKLMTDPFVGQLTFVRVYSGVLQSGSSVYNPIRGKKERIGRILQMHANQREEIKEILAGDIAACVGLKEVTTGETLCDIDSPITLVKMIFPEPVISQAVEPKTKADQEKMGIALGRLAAEDPSFRVRTDEESGQTIISGMGELHLEIIVDRMKREFGVEANVGKPQVAYRETIRDLVKDVEGKFVRQSGGKGQYGHVVLTVEPQEPGAGFQFVDAIKGGVVPREFIPAVEKGLIDTLPNGVLAGFPVVDVKVTLTFGSYHEVDSNENAFKMAASMGFKDGMRKAKPVILEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGMDDMVGGGKVIKAEVPLSEMFGYSTSLRSATQGRATYTMEFKHYSEAPKNVADAIITARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_STRU0
Sequence: MKVIRVKNQEEGGQVAFSLLKESLAHGAKTLGLATGSTPLTFYKEIVKSDLSFSDVTSINLDEYVGLPVEHDQSYDYFMRENLFNHKPFKENYLPNGLAKDLSVEVSRYDNLIAEHPIDFQILGIGRNGHIGFNEPGTPFDIRTHVVDLEESTIEANSRFFASKEDVPKQAVSMGIASIMESKMIVLMAFGKEKAYAVKEMITGPITESLPASVLQNHDNVIVIVDEEAASELD
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ATPD_DESVH
Sequence: MTGNIVARRYARALFALGKKSGLSDLETFGNDLAALAGTLETAPELVRMFRNPVFTPDEKRNVIAKLLDKLKVCPTVRNFCLLLADRERLAFIQDIQAYYGILLDAEKGVIRGELVTAIELANAKRDKVKAQLEAQAGRKLELGFSVDKNILGGVVLKVGDRILDASLRAQLGILKDNIKRGE
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THII_LACDB
Sequence: MQYTEIMIRYGELSTKGKNRKDFINRLASNVQKVLHDFPDLKIQTHHDRMHILLNGTPFEPVNDRLKVVFGIQTYSPVIKTEKSLEAIEKTALELMQATYKAGMTFKVNTRRSDHKFIYDTNQLNQMVADYLYNHMEGLQAEMKHPDMVLLLEIRQDGAYISNQLLHGAGGMPVGTAGKAVMMLSGGIDSPVASYLAMKRGVNIEMVHFFSPPYTSEKALAKAKELTSILAKYSGRINFIEVPFAEIQETIKEKLPEGYLMTVQRRFMLRLADIIREKRHALAIFNGESVGQVASQTLESMSAINDVTTTPVLRPVATMDKTEIIAKAEEIGTFDLSIQPFEDCCTIFAPPRPKTKPKIDKAREYESRLDVDGLIERALAGVKVTPIYPGQSFLDDLDEEDADLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQV8_CAEEL
Sequence: MSEQDSSSPKYMRFLLGNFTSAEMVTDGNFLIYCIEMGLLVIGVLENIFMIGAVFSTSCLHLNLRILICNCCLGFILMAVGRAMIAVPLCIAHLRDVDISSHAWCFIANAVHHSSADSVCLSFVFIMLERTAGTIWSKDYEKTKIHIFPCIFAFLQWFIPMFMILGNFLDRANRMEHFLLYPHLPCQIEYLTPTMFMITIFIIVIGFIASVGGITIVYNKNIKKYNTRDIWFNTVNLSERYQITENIRSTHLLFPLLALMLIFSTLSVSVLIYGGYWVSVMTKEPARFEEVVKWFGRGGEAAQLFDIITAIYTISFPICAFICHPNLFRFLRKFIGWNSYAVRPSNLNEIGGFEMSTAPIRTQTEFHFQELSRQWNT
What are the official names of this protein?
Probable G-protein coupled receptor F27E5.8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KHSE_MYCSK
Sequence: MTQTLPAGLTATATVAASSANLGPGFDSLGLALSLYDEIVVETVDSGLTVTVEGEGAGQVALDSSHLVVRAIEAGLRATGCIAPGLVVRCRNDIPHSRGLGSSAAAVVGGLAAANGLVSQTDWTPLTVEQLIQLSSAFEGHPDNAAAAVLGGAVVTWTDGAGAQARYAAAPLRVHPDIHLFPAIPQQRSSTAETRVLLPDTVSHTDARFNLSRAALLVVALTERPDLLMAATEDVLHQPQRAAAMPASAEFLRVLRGCGVAAVLSGAGPAVIALSTEPVLPAEAVEFGIANGFTIAEMAVGDGVRWSTGVAAGR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CODY_STAAT
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHSEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_CALS8
Sequence: MFYTTVGKIIKELNLECLTEISNIEERKIKDMNLNRPALQLMGFFEYFDEQRVQIIGISEMAYLKTMTKTQRRNAIEKLFQRDIPCVIITSNQEPFDEFLEFSKKYGIPLLRTSEVTTRFMTNLSTFLTHELAPRITRHGTLVNVYGEGVLMLGESGVGKSETALELVKRGHILVADDAVEIRKVSEKTLVGEAPEIIRHLIEIRGIGILDVKNLFGVGCVKDSERIDLVIQLETWKTDKEYERLGLHDQYIEILGIKVPTLVIPVRPGRNLAIIVEVAAMNNRQKKMGYNAAKALTERLQRQMSRNGNE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: ACYP_PYRAB
Sequence: MGIVRAHLRIYGRVQGVGFRWSMQREARKLGVNGWVRNLPDGSVEAVLEGEEERVEALIGWAHQGPPFARVTRVEVKWEEPKGEKGFRIVG
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: UBIG_ECOUT
Sequence: MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-octaprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone-8 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: VA0D2_ARATH
Sequence: MYGFEALTFNIHGGYLEAIVRGHRAGLLTTADYNNLCQCENLDDIKMHLSATKYGPYLQNEPSPLHTTTIVEKCTLKLVDDYKHMLCQATEPMSTFLEYIRYGHMIDNVVLIVTGTLHERDVQELIEKCHPLGMFDSIATLAVAQNMRELYRLVLVDTPLAPYFSECLTSEDLDDMNIEIMRNTLYKAYLEDFYNFCQKLGGATAEIMSDLLAFEADRRAVNITINSIGTELTREDRKKLYSNFGLLYPYGHEELAICEDIDQVRGVMEKYPPYQAIFSKMSYGESQMLDKAFYEEEVRRLCLAFEQQFHYAVFFAYMRLREQEIRNLMWISECVAQNQKSRIHDSVVYMF
What is the function of this protein?
Subunit of the integral membrane V0 complex of vacuolar ATPase.  Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.
What are the official names of this protein?
V-type proton ATPase subunit d2, V-ATPase subunit d2, Vacuolar H(+)-ATPase subunit d isoform 2, Vacuolar proton pump subunit d2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: SYP_HELP2
Sequence: MLFSKLFAPTLKEPPKDAVLKSHKHLAQAGYIYQVGSGIYNFLPLAKKVLDKIENITHKRMQEHGAQNILMSFVVLASLWEKSGRLDKYGKELLVFKDRKDNDFVLSPTLEENITEIAANFIKSYKQLPVHLYQIHTKFRDEIRPRFGLVRAREFIMKDGYSFHEDAESLDKEFLNTQSAYKEILSDLGLDFRIVEADSGAIGGSKSREFVVLTECGEDTIVVCQNCDYAANIEIAKRSKRPEPLNVPKAQLAKFPTPNTTSAQSVAEFFKTEPYFVLKALVRKVIHKDKETLACFFVRGDDNLEEVKALNALNIIGANALELREANEEDLNKAGLIAGFIGPYGLKKHVSYIIFDEDLKESDCLIVGANEKDFHAVGVDLKGFENLVYADIVQVKESDRCPNCQGELKYHKSLEVGHIFKLGQGYAKSLKASFLDKNGKEQFFEMGCYGIGISRLLSAILEQKSDDLGCVWTKNTAPFDVVIVVSNLKDEAQKKLAFEVYERLLQKGVDALLDDRDARFGAKMRDFELIGERLALIVGKQTLESKEFECIKRANLEKQTIKDIELEEKILEMLASE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_FRAT1
Sequence: MLISVLKSKISYATVTGKDLFYVGSITIDSEIMKQANIIENEKVQVVNLNNGERLETYVIKGEPNSKTIALNGPAARRCEIGDQLFIISYTQVDPTRENIKPKLVDLKTGD
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_OLEA2
Sequence: MAVVKVYDQDKKETGELTLAPEVFEVEVRPEILNLVVRAQRAAKRAGTHSVKTRSTISGGGAKPWRQKGTGRARSGSNRSPVWRGGAVVFGPQPRDYSFKVNKKVRKLALKMALSSRLAEENLMVVKGIELPEVKTKHMVKVAGALGLGKALVVTPEMDDKLVLSARNIPGITLMTPEQLSVFEILKHAQLVLLEGAVEPVQERLK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: YAEH_SHIFL
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: Y589_RICBR
Sequence: MFNQLSDEQKMLKKLALLSGIKPCTASSMLFSFPYSQQKLIDASTQKLFDLFGKLRNTDRLKFLIEEAIDRGIDIDVQDKDGFTLLHKSINERDYNIAGFLLERKANPNIHDRDIVTPLNRIAGKPLSKTEEDFHMAKLLLQKGALTEPTDFSGWTPIQYAVFNEKIGIVELLIDYGANLDIIVPKGFYKGKNLIELVRAISSIFSDQSLNKQLQTLLKLATACQNNDFGLVDYSVKKENSDTEDDSVTKEDIEKFINHKISIKPSVKLLPKYLKELIRLKGFLETKEEFIKDNTIKRLEDNINSKSSLKYLLLSKIVESPSLYKFDVGMPEDLKESLEEHGLKLVGDID
What are the official names of this protein?
Putative ankyrin repeat protein RBE_0589.
Protein: BLI4_CAEEL
Sequence: MRISIGRIAWQILAVLIAVAFTIEHDSICDESIGACGEPIHTVIRLAKRDDELARRIAADHDMHVKGDPFLDTHYFLYHSETTRTRRHKRAIVERLDSHPAVEWVEEQRPKKRVKRDYILLDNDVHHSNPFRRSVLNRDGTRRAQRQQPQSPREIPSLPFPDPLYKDQWYLHGGAVGGYDMNVRQAWLQGYAGRNVSVSILDDGIQRDHPDLAANYDPLASTDINDHDDDPTPQNNGDNKHGTRCAGEVAALAGNNQCGVGVAFKAKIGGVRMLDGAVSDSVEAASLSLNQDHIDIYSASWGPEDDGKTFDGPGPLAREAFYRGIKNGRGGKGNIFVWASGNGGSRQDSCSADGYTTSVYTLSISSATYDNHRPWYLEECPSSIATTYSSADFRQPAIVTVDVPGGCTDKHTGTSASAPLAAGIIALALEANPELTWRDMQHLVLRTANWKPLENNPGWSRNGVGRMVSNKFGYGLIDGGALVNMAKTWKTVPEQHICTYEYRLANPNPRPIVGRFQLNFTLDVNGCESGTPVLYLEHVQVHATVRYLKRGDLKLTLFSPSGTRSVLLPPRPQDFNANGFHKWPFLSVQQWGEDPRGTWLLMVESVTTNPAATGTFHDWTLLLYGTADPAQSGDPVYSATPATSQGVLSRVHQLTSQVEESAPISFPDLTSAGNCHDECNGGCTESSSATSCFACKHLTQTLRNKGGSGFKCVQKCDDTYYLDGDKCKMCSSHCHTCTKAEVCETCPGSLLLIDVDNMPHYDHGKCVESCPPGLVADYESNLVQAKCIWRKDLCGDGYYINAVGKCDLCDSSCETCTAPGPMSCEKCSKGYGKGSIGYCRPCCPEGSTKSWQCEDCSKPDPTLLIDSNKSSGFGLMFWIVVSLIAACGICACKKCASETKSSNVEYAPLAQYNATNGAINLGAHTDDEDDDEDEVFVNPQIV
What is the function of this protein?
Serine endoprotease which cleaves proproteins at paired basic amino acids (Probable).  Involved in cuticle biosynthesis probably by cleaving pro-collagen into its mature form.  Acts in ASEL sensory neurons to regulate high salt chemotaxis responses probably by cleaving insulin-like protein ins-6 into its mature and active form (PubMed:24013594).  Essential for embryonic and larval development (PubMed:7774813, PubMed:10903434, PubMed:19716386).  isoform a, isoform e, isoform f, isoform g and isoform h are involved in cuticle biosynthesis but are dispensable for larval development (PubMed:7774813, PubMed:10903434).
What are the official names of this protein?
Endoprotease bli-4, Blisterase, Blistered cuticle protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ARC5_ARATH
Sequence: MAEVSAKSVTVEEMAEEDDAAIEERWSLYEAYNELHALAQELETPFEAPAVLVVGQQTDGKSALVEALMGFQFNHVGGGTKTRRPITLHMKYDPQCQFPLCHLGSDDDPSVSLPKSLSQIQAYIEAENMRLEQEPCSPFSAKEIIVKVQYKYCPNLTIIDTPGLIAPAPGLKNRALQVQARAVEALVRAKMQHKEFIILCLEDSSDWSIATTRRIVMQVDPELSRTIVVSTKLDTKIPQFSCSSDVEVFLSPPASALDSSLLGDSPFFTSVPSGRVGYGQDSVYKSNDEFKQAVSLREMEDIASLEKKLGRLLTKQEKSRIGISKLRLFLEELLWKRYKESVPLIIPLLGKEYRSTVRKLDTVSKELSSLDEAKLKERGRTFHDLFLTKLSLLLKGTVVAPPDKFGETLQDERTQGGAFVGTDGLQFSHKLIPNAGMRLYGGAQYHRAMAEFRFLVGAIKCPPITREEIVNACGVEDIHDGTNYSRTACVIAVAKARETFEPFLHQLGARLLHILKRLLPISVYLLQKEGEYLSGHEVFLKRVASAFNSFVESTEKSCRDKCMEDLASTTRYVTWSLHNKNRAGLRQFLDSFGGTEHNTTSGNAIGFSLPQDALGGTTDTKSRSDVKLSHLASNIDSGSSIQTTEMRLADLLDSTLWNRKLAPSSERIVYALVQQIFQGIREYFLASAELKFNCFLLMPIVDKLPALLREELENAFEDDLDSIFDITNLRQSLDQKKRSTEIELRRIKRIKEKFRVMNEKLNSHEFAQNLKAPSVQH
What is the function of this protein?
Mechanochemical GTPase component of both plastid and peroxisome division machinery (PubMed:32005784).  Required for the last steps of plastid division specifically in mesophyll-cell, when the narrow isthmus breaks, facilitating the separation of the daughter plastids (PubMed:29466386).  Necessary for peroxisome activities.  Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency (PubMed:29466386).
What are the official names of this protein?
Dynamin-like protein ARC5, Dynamin-related protein 5B, Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 5, AtARC5.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Plastid, chloroplast outer membrane; Peripheral membrane protein. Peroxisome. Cytoplasm, cytosol. Note=Plastid equatorial positioning (in a discontinuous ring shape) mediated by PDV2 in complex with ARC6 and dissociation from the outer envelope membranes (OEMs) is triggered by PDV1; this localization with OEMs is repressed by phosphatidylinositol 4-phosphate (PI4P) (PubMed:32005784, PubMed:25736058). Dynamic subunit exchange within chloroplastic DRP5B rings with a cytosolic pool during chloroplast membrane constriction in a GTPase activity-dependent manner (PubMed:32005784).
Protein: RL30_ACIBT
Sequence: MKTIKVTQTKSSSHRLKNHKLCLQGLGLRRIGHTVEVQDTPSNRGMINKVYYMVSVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: MSXA_DANRE
Sequence: MVLTQNVDTFSGMISANHKSKVSSDEDDDDHGSRSVRTQSLPFSVDALMSTKERSESTSQGSIHMTRIINQDDRSIYSDSVDFIKRRESAKEDSAWINKPRLSTSPRSQSPTICPLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELERFKMASKPILHPGLTLPFPLCTQPQTAALVCGQSFPFSRHMLPFAPIGIYSTPMGYSMCHLSKDGYSVEPV
What is the function of this protein?
Probable morphogenetic role.
What are the official names of this protein?
Homeobox protein MSH-A.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: I1BC_CONRA
Sequence: MKLCLTFLLVLMILASVTGEKSSKHTLSRAARVKNRGPSFCKADEKPCKYHADCCNCCLGGICKPSTSWIGCSTNVFLTR
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels (By similarity).  Causes circular motion, convulsions, copious urination, rigid paralysis and death upon intracranial injection into mice.  Causes unbalanced swimming, swimming in diagonal and vertical motion and death, when injected intraperitoneally into goldfish.  L-Leu and D-Leu forms are active on both nerve and muscle.
What are the official names of this protein?
Iota-conotoxin-like r11c, R11.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_THESQ
Sequence: MRINPGEITKVLEEKIKSFEEKIDLEDTGKVIQVGDGIARAYGLNKVMVSELVEFVETGVKGVAFNLEEDNVGIIILGEYKDIKEGHTVRRLKRIIEVPVGEELLGRVVNPLGEPLDGKGPINAKNFRPIEIKAPGVIYRKPVDTPLQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQGVYCIYVAIGQKKSAIARIIDKLRQYGAMEYTTVVVASASDPASLQYIAPYAGCAMGEYFAYSGRDALVVYDDLSKHAVAYRQLSLLMRRPPGREAYPGDIFYLHSRLLERAVRLNDKLGGGSLTALPIVETQANDISAYIPTNVISITDGQIYLEPGLFYAGQRPAINVGLSVSRVGGSAQIKAMKQVAGMLRIDLAQYRELETFAQFATELDPATRAQIIRGQRLMELLKQEQYSPMPVEEQVVVLFAGVRGYLDDLPVEEVRRFEKEFLRFMHEKHQDILDDIKTKKELTSETEEKLKKAIEEFKTTFRV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.