PharMolix/UniProtQA huggingface dataset:
Protein: YJGA_ECO5E
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: NCAP_IBVDE
Sequence: MASGKATGKTDAPAPVIKLGGPKPPKVGSSGNASWFQAIKAKKLNSPQPKFEGSGVPDNENLKTSQQHGYWRRQLRFKPSKGGRKPVPDAWYFYYTGTGPAADLNWGDSQDGIVWVAAKGADVKSRSNQGTRDPDKFDQYPLRFSDGGPDGNFRWDFIPLNRGRSGRSTAASSAASSRAPSRDGSRGRRSGSEGDLIARAAKIIQDQQKRGSRITKAKADEMAHRRYCKRTIPPGYKVDQVFGPRTKGKEGNFGDDKMNEEGIKDGRVTAMLNLVPSSHACLFGSRVTPKLQPDGLHLKIEFTTVVSRDDPQFDNYVKICDQCVDGVGTRPKDDEPRPKSRSSSRPATRTSSPALRQQPQKKEKKPKKQDDEVDKALTSDEERNNAQLEFDDEPKVINWGDSALGENEL
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the gammacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: MC6ZB_XENLA
Sequence: MDLVDPSQSAAAAAGTQLVKDEVAEKCQKLFQDFLEEFRGSDGELKYQSDAEELIRPERNTLLVSFVDLEQFNQQLATTIQEEFYRVYPYLCRAVKAFARDHGNIPQNKEFYVAFQELPTRHKIRELTTPRIGSLLRISGQVVRTHPVHPELVSGTFLCLDCQTLVRDVEQQFKYTQPSICRNPVCANRKRFMLDTNKSRFVDFQKVRIQETQAELPRGSIPRSVEVILRAEAVESCQAGDRCDFTGSLIVVPDISQLSTPGVRAETSSRVGGREGYEAEGVQGLRALGVRDLSYKLVFLACYVCPTNPRFGGKDLHEEDMTAESIKNQMSVKEWEKVFEMSQDKNLYHNLCTSLFPTVHGNDEVKRGILLMLFGGVPKSTMEGTSLRGDINVCVVGDPSTAKSQFLKHVEEFSPRAVYTSGKASTAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDTKDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVGGRYDRAKSLKQNVNLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYTLDEVRRYLLFARQFKPKISKESEDFIVEQYKRLRQRDGSGVTKSAWRITVRQLESMIRLSEGMARMHCSDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEDEHEVEEPQEGINGDADVPNGVNGHINGINGHAEETNAAPPKPSLRLNFAEYKRISNLLVLQLRKIEDEDDENETSQRKSELINWYLKEIESEIDSEEELVNRKQIIDKVIHRLVHYDQILIELIQTGLKGTEDENVAKEEDPYLVVNPNYILED
What is the function of this protein?
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.  The existence of maternal and zygotic forms of mcm3 and mcm6 suggests that specific forms of mcm2-7 complexes may be used during different stages of development.  May replace mmcm6 in the mcm2-7 complex.
What are the official names of this protein?
Zygotic DNA replication licensing factor mcm6-B, Zygotic minichromosome maintenance protein 6-B, zMCM6-B, zMCM6b.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses.
Protein: RL20_LARHH
Sequence: MPRVKRGVTARARHKKVLALAKGYRGRRKNVYRVAKQAVMKAGQYAYRDRRQRKRQFRQLWIARINAAARECGLSYSKFMNGLKKASIEIDRKVLADLAVFEKAVFAQLVEKAKASLAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL7_RICAH
Sequence: MADLAKIEEQLSSLTLMQAAELVKMLEEKWCVSAAAPVAVAAAGAAPAAEAVAEKTEFEIVLIAAGDKKVEVIKAVKDITGLGLIEAKKLVDEAPKLMKSNVKKAEAEEIKGKLEAAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DYN3_HUMAN
Sequence: MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQGTNLPPSRQIVIRKGWLTISNIGIMKGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVPSRRPPPSPTRPTIIRPLESSLLD
What is the function of this protein?
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.  Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).
What are the official names of this protein?
Dynamin-3, Dynamin, testicular, T-dynamin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
Protein: RL36_DESAH
Sequence: MKVRASVKKICKDCKIIRRKGVIRVICITKRHNQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PUR5_ECO45
Sequence: MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVNTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIKTSDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O16K_CONEA
Sequence: VLIIAVLFLTACQLTTAETYSRGRQKHRARRSTDKNSKWTRECTRSGGACNSHTQCCDHFCSTATSTCI
What are the official names of this protein?
Conotoxin Eb6.20.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PAND_PORGI
Sequence: MYVEVLKSKIHRVTITEANLNYVGSITIDEDLMDAANIIAGEKVQIVDNNNGARLETYTIPGKRGSGVICLNGAAARIVHPGDIIIIMAYAWMPMEEAKVFKPAVVFPDTATNKIILK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_RICBR
Sequence: MTKVITRFAPSPTGMLHVGNIRAALLNWLYAKKHDGQFILRFDDTDLERSKQEYKDAIRADLKFLNLNWDQTFNQLSRLSRYDEIKKLLLDKKRLYACYETPEELELKRKFQLSKGLPPIYDRAALNLTEDQIQKYIEQGRKPHYRFLVNHEPITWHDMIKGEVKYEGKALSDPIVIRADGSMTYMLCSVIDDVDYEITHIIRGEDHVSNTAIQIQMFEALDKYPPTFGHLSLIINKDEKISKRVGGFEIATLREEVGLEAMAIASFFSLLGSSAQIIPHKKMDELVKHFEISSFSKSPTIYQPEDLERLNHKLLISLEFNEVKDRLKEIDAEYIDENFWLSVRPNLKKLFDAKDWWEICHKTPNIQDLNLDKEYLKQAAELLPEEEITTETWGIWTKKLAAITNRKGKELFLPLRLALTGKESGPEISKVLPLIKREEIVKRLT
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UDP_ECOLI
Sequence: MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL
What is the function of this protein?
Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate (PubMed:16751).  Shows weak activity towards deoxyuridine and thymidine (PubMed:16751).  The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable).
What are the official names of this protein?
Uridine phosphorylase, UPase, UrdPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTCC_BURMA
Sequence: MSFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDPASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAHHAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYAYLGDARNNMGNSLLLIGAKLGMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEPVEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLQDGIEVTDEVFESPRCIAFEQAENRMHTIKAVLVSTLGGI
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_CAMJR
Sequence: MRRRKAPVREVLPDPIYGNKVITKFINSLMYDGKKSTATTIMYGALEAIDKKGGEKKGIDIFNDAIENIKPLLEVKSRRVGGATYQVPVEVRPARQQALAIRWIISFARKRSERTMIDKLAAELLDAANSKGASFKKKEDTYKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: Y2419_PSEU2
Sequence: MSIESSSTESSPNTEALQLNGTEVRILGCLIEKQATNPETYPLTLNALVTACNQKTSRDPVMNLTQGQVGQSLRALEGRGLTRLVMGSRADRWEHRVDKGLELVPAQVILTGLLLLRGPQTVNELLTRSNRMHDFEDSEQVVHQLERLIARGLAMLVPRQSGQREDRYMHLLGDPESLQELLAARQQAPERHSASPAANSRIDELEARVAALEERLARLEHAEE
What are the official names of this protein?
UPF0502 protein Psyr_2419.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: Y1032_METJA
Sequence: MEKEGVKNYLVLVVDIDDDIGRKAGLNTPILGREENIKALIKLGLADPGDSDVNAILGGVKIYDELKASGKDVEIATISGDVDVESEKCALRIKEQIDFLLYLYNPDFIYLVSDGKEDEMILKYLESKNIFVWKKRVIVKQSETLESTYYLIQEFIKKTMEEYIPLILTFIGFSLILYAIFADIGWRIVVGIIGLYILSEGVGVRKLLMEKIKKKEEFDVGRVFPISASISIFILIIGLIYSLSSINKTSSTLTEFIGEFLLHFVDSLTLSLLILMVGKFVDTIINSEKDLLEILKKYFFCLICIFISRELIISGGEYLLKKISFIMFVMCVIIYISIVIILSVILFTKSSKEDKFKKLKNSITKG
What are the official names of this protein?
Uncharacterized protein MJ1032.
What is the protein family that this protein belongs to?
To A.fulgidus AF2058.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXD1_GLOVI
Sequence: MGVQFSAAELTDLVGGELSGDPGRLVVGARPPEEAEGGDLTFALDLHARKLIETTRAGVAITPVRWPFEHLTQIVVANPRLAMAQVLAHMFPQPIAMPPAGIHPSAVVHPSAVVHPSASVAALVYVGPRAAVGANTHLFPGVYVGAEAVVGSECLIYPNVVLMDGIRLGDRVVIHAGSVLGSDGYGFVPTGERHLKVPQVGTVVIGDDVEVGANVAVDRATMGQTEIQAGTKIDNLVHIGHNDRIGRHCLIVSQVGLAGSVKVGDRTVIAGQAGVANQTTVGADCLVLARSGVTKDLPDHSKVSGFPAQDHLLELKQQAARSRLPQIVEQMRQMQRRIEQLEVQLLGRL
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: DNLJ_STAA2
Sequence: MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEYKTVDSPTVRVGGEAQASFKKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTAILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDAVTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKIIQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLGIRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQKLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSSVTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DTD_ALKCK
Sequence: MRVLVQRAKRGSVRVDQKTVGDIGPGLVLLVGIHQEDTEADVRFCAEKVAHLRIFEDSSAKMNESVLDQGGSVLSISQFTLYGDCKKGRRPNFMRAAKPEKAKLLYERFNSYLRELGLVVETGEFGAMMEVELINDGPVTILVESE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_THENN
Sequence: MIRVAAAGGGTGGHLYPLLAILETLSKDVETKVLFFAVKGKIDEKVVKQEHPEYEVVTLDVRGLFRPLYHPKNFWRAAKVVNAILKAKKELLRFKPDVIVLTGGYISGVVGLAAKNMGVPIFLHEQNVVPGLAVKTVAKYARKIFVSFERTREFLTEWKDRVLFTGCPVRETKEEVDLEDFVLVLGGSLGSDLINSLMEEVYRRISCIRFVHSTGSRRWAERLSVFPNVTAHPYIENMSSFWKKARASISRAGASTIGEMIYYGVPGVLIPWEGSAESHQLENALEAERLGYAIVVREKEATPQKIIEAIDKTMKKGKIEKMKENPATIISREILGEIR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MATB_NEUCS
Sequence: MDGNSTHPAPNLKTTMAWSRISNQLGHWNDRKVIAIPLSDFLNTHPDIQSGIIAEFKKATGEEGMFARDPESLGIMLLGPVKLFKPDSVVVDGNLFWDPKGIHASAPKEQQKKAKIPRPPNAYILYRKDHHREIREQNPGLHNNEISVIVGNMWRDEQPHIREKYFNMSNEIKTRLLLENPDYRYNPRRSQDIRRRVSPYLKIKLLNYDVNGNLLWGTVNAEDAALIRTHFHGVVRVEEMDDGCRIVCRPVAGSRKLRAAVVDTWMPRYTVDTTPVTEDDDAQAFNFNDPLGGAYFPLNEHLWITVNQNPPFNAPPPNPNPHLDFVHPDGMEAVVHNVQNMIAQVQEANEAAALTLPPPPPLRLLSLRLWLMIPLTQLSFPL
What is the function of this protein?
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion.  Transcriptional activator that induces the transcription of a-specific genes like mating factor mfa-1.  Required for mating as an a-cell, blocking of heterokaryon formation (vegetative incompatibility) and for perithecium induction.
What are the official names of this protein?
Mating-type protein a-1, Mt a-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH606_BRADU
Sequence: MAAKEVKFSVDARDKMLRGVDILANAVKVTLGPKGRNVVLDKSFGAPRITKDGVTVAKEIELEDKFENMGAQMVREVASKSADAAGDGTTTATVLAQAIVREGAKSVAAGMNPMDLKRGIDLAVEAVVADLVKNSKKVTSNDEIAQVGTISANGDAEIGKFLADAMKKVGNEGVITVEEAKSLETELDVVEGMQFDRGYISPYFVTNADKMRVEMDDAYILINEKKLSSLNELLPLLEAVVQTGKPLVIVAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLQDIAILTGGQAISEDLGIKLENVTLNMLGRAKKVMIDKENTTIVNGAGKKADIEARVSQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKERKDRVDDAMHATRAAVEEGIVPGGGVALLRASEQLKGLRTKNDDQKTGVEIVRKALSAPARQIAINAGEDGSVIVGKILENKTYAYGFDSQTGEYVNLVTKGIIDPTKVVRTAIQNAASVAALLITTEAMVAELPKKGGAGPAMPPGGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 6, 60 kDa chaperonin 6, Chaperonin-60 6, Cpn60 6.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_STAA2
Sequence: MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3_ARATH
Sequence: MEAKLLKPAFYNSPNLNLTNSSRLISRLSIWNDKSKVGLSSGSLFLRLSAASPIRYSRGLLRVDESEYLKLESIRHSLIRQEDSIIFNLLERAQYRYNADTYDEDAFTMEGFQGSLVEFMVRETEKLHAKVDRYKSPDEHPFFPQCLPEPILPPIQYPQVLHRCAESININKKVWNMYFKHLLPRLVKPGDDGNCGSAALCDTMCLQILSKRIHFGKFVAEAKFRENPAAYETAIKEQDRTQLMQLLTYETVEEVVKKRVEIKARIFGQDITINDPETEADPSYKIQPSLVAKLYGERIMPLTKEVQIEYLLRRLD
What is the function of this protein?
May play a role in chloroplast biogenesis.
What are the official names of this protein?
Chorismate mutase 3, chloroplastic, AtCM3, CM-3.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLPA_ECO57
Sequence: MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor (By similarity).
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit A, G-3-P dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase.
Protein: RNPA_NEIG2
Sequence: MDYRFGRQYRLLKTDDFSSVFAFRNRRSRDLLQVSRSNGNGLDHPRIGLVVGKKTAKRANERNYMKRVIRDWFRLNKNRLPPQDFVVRVRRKFDRATAKQARAELAQLMFGNPATGCGKQV
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: COX2_CERGA
Sequence: MAHPVQLGLQDATSPVMEELITFHDHALMAMSLISLLVLYALFSTLTTKLTNTNITDAQEMEIIWTILPAIILVLIALPSLRILYLTDEVNNPSFTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLNPGDLRLLEVDNRVVLPIEAPVRMMITSQDVLHSWTIPTLGLKTDAVPGRLNQTVFTATRPGVYYGQCSEICGANHSFMPIVAELIPLKIFEMGPVFTL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.