PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_ESCF3
Sequence: MRSNYIVIEGLEGAGKTTARNVVVETLEQLGIREMIFTREPGGTQLAEKLRSLVLDIKSVGDEVITEKAEVLMFYAARVQLVETVIKPALAKGTWVIGDRHDLSTQAYQGGGRGVDQTMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDASIRTIDATQSLECVMADIRQTVTTWVKEQGA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RUVB_CHRSD
Sequence: MIDTDRLIAAQPQGSEVHVDHAIRPRRLAEYIGQPRVREQLDIFISAARKRGDSLDHTLVFGPPGLGKTTLANIIAAEMDVDIKSTSGPVLERAGDLAAMLTNLQAGDVLFIDEIHRLPASVEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPAFTLVGATTRAGLLTSPLRDRFGIVQRLEFYAVEELTEIVVRSAHLLGVDAERDGAAEIARRARGTPRIANRLLRRVRDFAEVRGDGRLTAAIADQALNMLHVDRHGLDHMDRRLLMAMIEKFDGGPVGVDSLAAAISEERDTIEDVLEPYLIQQGFMMRTARGRVVTRSAYEHFGLTPTDAVATAVPLTPPGESDA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HHLA2_HUMAN
Sequence: MKAQTALSFFLILITSLSGSQGIFPLAFFIYVPMNEQIVIGRLDEDIILPSSFERGSEVVIHWKYQDSYKVHSYYKGSDHLESQDPRYANRTSLFYNEIQNGNASLFFRRVSLLDEGIYTCYVGTAIQVITNKVVLKVGVFLTPVMKYEKRNTNSFLICSVLSVYPRPIITWKMDNTPISENNMEETGSLDSFSINSPLNITGSNSSYECTIENSLLKQTWTGRWTMKDGLHKMQSEHVSLSCQPVNDYFSPNQDFKVTWSRMKSGTFSVLAYYLSSSQNTIINESRFSWNKELINQSDFSMNLMDLNLSDSGEYLCNISSDEYTLLTIHTVHVEPSQETASHNKGLWILVPSAILAAFLLIWSVKCCRAQLEARRSRHPADGAQQERCCVPPGERCPSAPDNGEENVPLSGKV
What is the function of this protein?
Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation.  Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
What are the official names of this protein?
HERV-H LTR-associating protein 2, Human endogenous retrovirus-H long terminal repeat-associating protein 2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GMHA_YERP3
Sequence: MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHLSCVSNDFGYDYVFSRYVEAVGREGDVLLGISTSGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH2_ALKMQ
Sequence: MDNHEEKRQRRVRYNGTHPKVFKEKYKELQPDKYADAVAKVIQKGSTPAGMHRSICVNEILEFLKITPGQTGLDATLGYGGHTLEMLKRLNSKGHLYAIDVDSIELPRTQERLEGLGYGSEILTIKQMNFSNIDQIALESGPLNFVLADLGVSSMQIDNPERGFSFKSEGPLDLRLNPNRGISAAARLKTISQDELQGMLLENADEPNSAAISRAIISEIKKGIDISTTTQLQQIIKDALKFIPQNTRKDEIKKSCQRCFQALRIDVNDEFEMLYEFLEKLPATLAEGGRVAILSFHSGEDRLVKKSFQRFFREGVYREIAPNFIRPSTEECNTNGRARSAKLRWAIKA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H 2, 16S rRNA m(4)C1402 methyltransferase 2, rRNA (cytosine-N(4)-)-methyltransferase RsmH 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_BRUAB
Sequence: MIQKNWQELIKPNKVDFITHGSRTHATVVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAVQIDGVLHEFSSIPGVREDVTDIVLNIKEIAIRMEGEGPKRMVVRKEGPGVVTAGDIQTVGDVEILNPEHVICTLDEGAEIRMEFTVNTGKGYVPADRNRAEDAPIGLIPVDSLYSPVRKVSYKIENTREGQVLDYDKLTLNIETNGSVTGEDAVAYAARILQDQLSIFVNFEEPQKEAPQEQVAELAFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLASMGLHLGMEIPAWPPENIEDLAKRYEDQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: FTSZ_MYCPU
Sequence: MSDLENFVPTANIKVIGVGGGGNNSVETMIQAGIQGVEFIVANTDIQALQRSSAPNFIHLGENKRGLGAGANPEVGKKAAEESIVEIKEKLKGADMVIITSGMGGGTGTGASPIIAKIARELGALTISIVTTPFEFEGNLRNKNAQEGIKNLRAVSDSIIIISNNKLLEQYGDAPMKDSFLFADTILKHTVKTITDIIAIPAHINLDFADVKTVMKDKGDALIGIGRASGKDRAVKAAIHAISSPIIETSIQGASHTIINITGSANLTLTEVHSAVNVIKNAVGPEMNTIFGATINESIGDEIYVSVIATGLSSSKKFNSEQEIKDEVSSMLKTMEIDLQASETKTILINDPLPKDEKMVLTSLLDRDSKILEKDDSQDDTLPFFLKRNV
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: BAKOR_MOUSE
Sequence: MASPSGKGSWTPEAPGFGPRALARDLVDSVDDAEGLYVAVERCPLCNTTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSQLKNKQEEFQKEVLKAMEGKRLTDQLRWKIMSCKMRIEQLKQTICKGNEEMKKNSEGLLKNKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLKSHYERLARLRRSHILELTSIIFPIDEVKTSGRDPADVSSETDSAMTSSMVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYNWVEEKKTTQGPDMEHNNPAYTISAALGYATQLVNIVSHILDINLPKKLCNSEFCGENLSKQKLTRAVRKLNANILYLCSSQHVNLDQLQPLHTLRNLMHLVSPRSEHLGRSGPFEVRADLEESMEFVDPGVAGESDASGDERVSDEETDLGTDWENLPSPRFCDIPSQPVEVSQSQSTQVSPPIASSSAGGMISSAAASVTSWFKAYTGHR
What is the function of this protein?
Required for both basal and inducible autophagy (PubMed:19270696, PubMed:19270693).  Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (By similarity).  Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:19270693).  Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (By similarity).  Enhances PIK3C3 activity in a BECN1-dependent manner.  Essential for the autophagy-dependent phosphorylation of BECN1 (By similarity).  Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation of PIK3C3 by AMPK (PubMed:23332761).  Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (By similarity).  Modulates the hepatic lipid metabolism (PubMed:22992773).
What are the official names of this protein?
Beclin 1-associated autophagy-related key regulator, Barkor, Autophagy-related protein 14-like protein, Atg14L.
What is the protein family that this protein belongs to?
Belongs to the ATG14 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Note=Cytosolic under nutrient-rich conditions (PubMed:20639694). Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:20639694). Accumulates on highly curved PtdIns(3)P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (PubMed:21518905). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (PubMed:24089209).
Protein: RNC_PSEPW
Sequence: MSASLARLERKLGYTFKDQDQMVLALTHRSYAGRNNERLEFLGDAILNFVAGEALFERFPQAREGQLSRLRARLVKGETLARLARGFDLGEYLRLGSGELKSGGFRRESILADALEALIGAIYLDADMQTARERVLAWLTDEFESLTLVDTNKDPKTRLQEFLQSRSCELPRYEVVDIQGEPHCRTFFVECEVVLLNNKSRGQGVSRRIAEQVAAAAALIALGVENGND
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNJ_RHIME
Sequence: MNDLATYNFAYLDEQTKRMIRRAILKAIAIPGYQVPFASREMPMPYGWGTGGVQVTASILGPDDVLKVIDQGADDTTNAVSIRAFFQKVADVAVTTRTTEATIIQTRHRIPEEQLREGQTLVYQVPIPEPLRFLEPRETETRKMHALEEYGLMHVKLYEDIARNGHIATTYAYPVKVEGRYVMDPSPTPKFDNPKMHMSEALQLFGAGREKRIYAVPPYTEVVSLDFEDHPFEVQKFDKPCALCGAENVYLDEVVLDDKGGRMFVCSDTDHCEDRRAHGHAGAMLAPAAKESQEAAE
What is the function of this protein?
Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP).
What are the official names of this protein?
Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase, PRPn C-P lyase.
What is the protein family that this protein belongs to?
Belongs to the PhnJ family.
Protein: MQO_SHISS
Sequence: MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDADKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: CGR1_ASPTN
Sequence: MSASESAPSAPPVKGMRKNGKNWHDSKKPFRPTAGMTSYAKRLEARKHQEAVKEHERELKEEKEAERQAHIQRIKDRRAAKEEKERYDKMAEKMHRKRVERLKRREKRNKLLNS
What is the function of this protein?
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
What are the official names of this protein?
rRNA-processing protein cgrA.
What is the protein family that this protein belongs to?
Belongs to the CGR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: 3BHS_VACCW
Sequence: MAVYAVTGGAGFLGRYIVKLLISADDVQEIRVIDIVEDPQPITSKVKVINYIQCDINDFDKVREALDGVNLIIHTAALVDVFGKYTDNEIMKVNYYGTQTILAACVDLGIKYLIYTSSMEAIGPNKHGDPFIGHEHTLYDISPGHVYAKSKRMAEQLVMKANNSVIMNGAKLYTCCLRPTGIYGEGDKLTKVFYEQCKQHGNIMYRTVDDDAVHSRVYVGNVAWMHVLAAKYIQYPGSEIKGNAYFCYDYSPSCSYDMFNLLLMKPLGIEQGSRIPRWMLKMYACKNDMKRILFRKPSLLNNYTLKISNTTFEVRTNNAELDFNYSPIFNVDVAFERTRKWLEESE
What is the function of this protein?
Catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids.  The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.  During viral infection, steroid production contributes to virulence by inhibiting the host inflammatory response.
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase, 3-beta-HSD.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
Protein: EMC3_DICDI
Sequence: MTESPIVLDVEIRNWVVIPILIVLFIVSALKLNISRIMQINSGKPQDVEKTMQMQTINRVRRLVSFYNRIPQKSFFIRKAYLCGTTGSKTNKGILSSIAPTQEDSNPMNMMFANSMFTDPSGITDMLKGNIMHLIPQVTMMSWVNHFFSGFVACKLPFFPLTIRFKTFLQRGIEMGSLDVSYVSSLSWYFLCWFGSEGINAILLGENMVSADSQLLQSSIEPGPPTQQTPIHKIYASEKENIEMIRYDSLMTNIEDRFLDNIKKKTSFDFNQINKNNNNNNNNTSNIKPKPIKSNLSNSKQSKRITYQKPSSLI
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 3, Transmembrane protein 111.
What is the protein family that this protein belongs to?
Belongs to the EMC3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL147_PLAVT
Sequence: MRGAFYVTTALLITNSIRTAAEANPPGRQPMSHHDGVVPGKSSPRRFLQGSHEPHDKFAVSAANEERMPEPSAKITASLSEEALDTVRKAAHFTFDLNAPPEETPTGMVEAYQVLRQKDPRTVTASHPKRTAEALTSLDEALGYANPKYSAGGQSKKLRTSVSFKATEVRNSISRDRMTPTPRTLSDDDVQNVHKLYMEHLERNLAVFAPTVGGRRE
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 147.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: DER_LACP7
Sequence: MSKSIVAVVGRPNVGKSTLFNALAGDRISIVKDTPGVTRDRIYADITWLDKQFTLVDTGGIEPESKDMMLTYMREQAEIAIATADVIMFVVDVRQGLLDADNKVADMLRRSGKPVILVVNKVDNFDKFMPDVYEFYNLGIGDPVPVSAASMLGFGDLLDLVVGHFPPEALEEEEDERPRIAIVGKPNVGKSSIINKLLGENRVIVSDVAGTTRDAIDTAVTWNKKDYVFIDTAGLRRKSKIKEELERFSIIRTVSAVERADVVVVVIDANEGVTEQDAKIAGIAHERGKGIIIAVNKWDAIEKDDKTIYKYTNRIREILSFLPYAEIMFLSAKTGQRVTKLFDSIEVVIQNRNLRISTGVLNEIMMEATALQQPPSDKGKRLRLYYITQVAVKPPTFVIFVNDKELMHYSYTRYIENKIREAFGFSGTSLKFFIRERKEND
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYE_SHEAM
Sequence: MTVKTRFAPSPTGFLHVGGARTALYSWLHARANQGEFVLRIEDTDLERSTQEAVDAILEGMEWLNLNWDEGPYYQTKRFDRYNEIIDQMLKAGTAYKCYCSKERLEAVREEQAAKGERQKYDGCCRGAAPRAEGEPHVVRFLNPQGGSVVFDDHVRGRIEIANEELDDLIIRRTDGSPTYNFCVVVDDWDMGITHVVRGEDHINNTPRQINILKALGAPIPEYAHVSMILGDDGAKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSMDELVEFFRLDDINKAASAFNSEKLLWLNQHYIKALDPEYVAKHLEWHMKDQGIDTSNGPALADVVTALSERAKTLKELAASSRYFYEDFEEFDADQAKKHLRGVALEPLKLVQQKLAALTEWTREAIHQAIEETATELEVGMGKVGMPLRVAVTGAGQSPGLDITLELIGKARSEQRISKAVDFVADRINS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AB15B_ARATH
Sequence: MGKEEEKESGRNKMNCFGSVRSIFMHADGVDWLLMGLGLIGAVGDGFTTPLVLLITSKLMNNIGGSSFNTDTFMQSISKNSVALLYVACGSWVVCFLEGYCWTRTGERQTARMREKYLRAVLRQDVGYFDLHVTSTSDVITSVSSDSFVIQDVLSEKLPNFLMSASTFVGSYIVGFILLWRLAIVGLPFIVLLVIPGLMYGRALISISRKIREEYNEAGFVAEQAISSVRTVYAFSGERKTISKFSTALQGSVKLGIKQGLAKGITIGSNGITFAMWGFMSWYGSRMVMYHGAQGGTVFAVAAAIAIGGVSLGGGLSNLKYFFEAASVGERIMEVINRVPKIDSDNPDGHKLEKIRGEVEFKNVKFVYPSRLETSIFDDFCLRVPSGKTVALVGGSGSGKSTVISLLQRFYDPLAGEILIDGVSIDKLQVKWLRSQMGLVSQEPALFATTIKENILFGKEDASMDDVVEAAKASNAHNFISQLPNGYETQVGERGVQMSGGQKQRIAIARAIIKSPTILLLDEATSALDSESERVVQEALENASIGRTTILIAHRLSTIRNADVISVVKNGHIVETGSHDELMENIDGQYSTLVHLQQIEKQDINVSVKIGPISDPSKDIRNSSRVSTLSRSSSANSVTGPSTIKNLSEDNKPQLPSFKRLLAMNLPEWKQALYGCISATLFGAIQPAYAYSLGSMVSVYFLTSHDEIKEKTRIYALSFVGLAVLSFLINISQHYNFAYMGEYLTKRIRERMLSKVLTFEVGWFDRDENSSGAICSRLAKDANVVRSLVGDRMALVVQTVSAVTIAFTMGLVIAWRLALVMIAVQPVIIVCFYTRRVLLKSMSKKAIKAQDESSKLAAEAVSNVRTITAFSSQERIMKMLEKAQESPRRESIRQSWFAGFGLAMSQSLTSCTWALDFWYGGRLIQDGYITAKALFETFMILVSTGRVIADAGSMTTDLAKGSDAVGSVFAVLDRYTSIDPEDPDGYETERITGQVEFLDVDFSYPTRPDVIIFKNFSIKIEEGKSTAIVGPSGSGKSTIIGLIERFYDPLKGIVKIDGRDIRSYHLRSLRRHIALVSQEPTLFAGTIRENIIYGGVSDKIDEAEIIEAAKAANAHDFITSLTEGYDTYCGDRGVQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSQSERVVQDALERVMVGRTSVVIAHRLSTIQNCDAIAVLDKGKLVERGTHSSLLSKGPTGIYFSLVSLQTTSG
What are the official names of this protein?
ABC transporter B family member 15, ABC transporter ABCB.15, AtABCB15, Multidrug resistance protein 13, P-glycoprotein 15.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VQ10_ARATH
Sequence: MSGRGKVKSEPMKVVFINTQYVETDARSFKTVVQELTGKNAIVAAGPFDSPSAFDGRCYDGGSKIGEDTRQLHGGGGGGGRMGTTTEFDRLFKEMPHMEELYKLWSEY
What is the function of this protein?
May modulate WRKY transcription factor activities.
What are the official names of this protein?
VQ motif-containing protein 10, AtVQ10, Tobacco rattle virus-induced protein variant 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS8_GLOC7
Sequence: MASNDTIADMLTRIRNACAVRHPTTKVPTTKMTRSIAQVLKQEGFIEDFSEAGEGVGKHLVISLKYKGKTRQPIITTLKRVSKPGLRVYSPCKDLPRVLGGIGIAIVSTSQGIMTDREARRQGVGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: COX3_DROSI
Sequence: MSTHSNHPFHLVDYSPWPLTGAIGAMTTVSGMVKWFHQYDMSLFLLGNIITILTVYQWWRDVSREGTYQGLHTY
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLAH_PSEPK
Sequence: MNAFTQIDELVMPLPLEPQGYTIAPSKQSPRLLELTFARETVEAFVQAVAQWPVQALEYKSFLRFRVGEILDELCQGTLRPVLLNTILDRATGGMLITPIGLDDVSQAEDMVKFTTACAHLIGRSNYDAMSGQFYARFVVVNSDNSDSYLRQPHRVMELHNDGTFVNQITDYVLMLKIDEKNMEGGNSLLLHLDDWEQCEAFFRHPLARREMRWTAPPSKKVAEDVFHSVFDTDAEGRPTMRYIDQFVQPENYEEGIWLNALSESLEGSGKKVSVPVGVGSFLLINNLFWLHGRDRFTPHEGLRRELMRQRGYVAFPKPLYQRGQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG) (PubMed:31064836).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate (By similarity).  Is extremely specific for glutarate, but it can use both 2-oxoglutarate and 2-oxoadipate (2OA) as a cosubstrate for L2HG formation (PubMed:31064836).
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: VSP4_CROAD
Sequence: MVLIRVLANLLILQLSYAQMSSELVTGGDECNRNEHRFLVALYDPDRFLCGGTLLNEEWVLTAAHCDRRNMWIKLGMHSKTVPNEDEQRRVPKEKFFCLSTKNYTLWDKDIMLIRLDSPVSNSEHIAPLSLPSSPPSVGSVCRIMGWGTISSNKETYPNVPHCANINILDYEVCLAAYPEFVLPATSRTLCAGILEGGKDSCKGDSGGPLICNGQFQGILSWGNDVCGYILQPALYTRVFDHLDWIQRIIAGNTDATCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine proteinase 4a, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSC_STAHJ
Sequence: MSQSSNITWHDSEVTKSDRQQQNGHKSVVIWFTGLSGSGKSTVSVELEKALFQLEKHSYRLDGDNVRHGLNKNLGFSPEDRKENIRRIGEVSKLLVDAGTIAITAFISPYRADRDEVREILEDGEFIEVYTECSVEACEQRDPKGLYKKARSGEIKEFTGISASYEAPHQPEITINTEHQSVEESVSTIIEYLKNKEII
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: DMP4_ARATH
Sequence: MEIKVDEGHQKGTKEDITRPLLEEDKDFPDIERTTWIQKAIGQTFQTTAHLANLLPTGTVLAFQLLSPIFSNGGQCDLVSKIMTSTLVAICGFSCFILSFTDSYKDKNGTICYGLATIHGFWIIDGSTTLPQELSKRYKLRFIDFVHAFMSLFVFGAVVLFDRNAVNCFFPSPSAEALEVLTALPVGVGVFSSMLFATFPTTRNGIGFPLSSK
What is the function of this protein?
Involved in membrane remodeling.
What are the official names of this protein?
Protein DMP4, AtDMP4.
What is the protein family that this protein belongs to?
Belongs to the plant DMP1 protein family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.