PharMolix/UniProtQA huggingface dataset:
Protein: PCOB_ECOLX
Sequence: MKRNLKAIPVLVAGLFTSQLSIAAGSVSADPHAGHDMSAMQMPADENFTEMTSMEPIVTESRTPIPPVTDADRKAAFGNLQGHAIHDSAINYLVLLDQLEWQRSDNTNNFSWSVNSWIGGDTDRIWLKSEGERSNGETEAAEAQLLWGHAVGPWWDLVAGVRQDFRPASARTWAAVGFQGLALYNFESEITGFVSNGGKAALRLGGEYDVLLTNRLILQPSYEVNFYSQDDESRGRGRGLTDTELGLRLRYEIRREFAPYIGVSWNQLYGKTSDMAKREGEKDHQVVFLAGARIWF
What is the function of this protein?
Required for the copper-inducible expression of copper resistance.
What are the official names of this protein?
Copper resistance protein B.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: MGT_STAHJ
Sequence: MKRSQRMNNSPERHSQYRNEPHYNTYYQPVGKPPKKKKNKRIFLRLFIIFVFIYALFIGLMYYLSSRANVDDLKTIENKSSYVSADNMPDYVKGAFISMEDERFYKHHGFDVKGTTRALFSTIGDRDVQGGSTITQQTVKNYYYDNERSFTRKLKELFVAHKVEQQYSKNEILSFYLNNIYYGSDQYTIESAANYYFGTTVNKNSDSMSQITVLQSAILASKVNAPSVYDISNMSDNFKNRIKTNLEKMKQQEYISDSQYQEALSQLNNY
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate.
What are the official names of this protein?
Monofunctional glycosyltransferase, MGT, Peptidoglycan TGase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FIXG_RHIME
Sequence: MLHQPKTKATVGRLDAETVNAARVRGPLYEKRRKIFPKRAEGRFRRFKWLVMLVTLGIYYLTPWIRWDRGAHAPDQAVLIDLASRRFYFFFIEIWPQEFFFVAGLLVMAGFGLFLVTSAVGRAWCGYACPQTVWVDLFLVVERFIEGDRNARMRLDAGPWSLDKIRKRVAKHAIWVAIGVATGGAWIFYFADAPSLMSSLVALDAPPVAYTTIGILTATTYVFGGLMREQVCTYMCPWPRIQAAMLDENSLVVTYNDWRGEPRSRHAKKAAAAGEVVGDCVDCNACVAVCPMGIDIRDGQQLECITCALCIDACDGVMDKLGRERGLISYATLSDYAANMALATSGGTAAIDPSRVRNAHGAFRDKVRHLNWRIVFRPRVLVYFGVWATVGFGLLFGLLARDRLELNVLHDRNPQFVVESDGSVRNGYMVKLLNMIPEQRTISLTIEGMPAATMRVAGQATGDGRRVTIGVEPDKVTPLKVFVTLPKGRFAEAEEGFSLIAEDPSSHERDVYQANFNLPGAAGR
What is the function of this protein?
FixG is predicted to be involved in a redox process.  The four proteins FixG, FixH, FixI, and FixS may participate in a membrane-bound complex coupling the FixI cation pump with a redox process catalyzed by FixG.
What are the official names of this protein?
Nitrogen fixation protein FixG.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS5_MARN8
Sequence: MSVNEQKAPELQEKLVQVNRVAKVVKGGRIFAFTALTVVGDGKGRVGFGRGKAREVPVAIQKAMEAARKNMVDVALDGTTLQYPVRAQHGGSKVFMQPASEGTGIIAGGAMRAVLEVAGVQNVLSKCYGSTNPVNVVRSTIKGLQAMKAPEDVAAKRGKSVEDILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: DNAK_ECOLC
Sequence: MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DAPA_PARUW
Sequence: MYLKGLYTALITPFTPTGQLDEEGLKKLIQIQLHHQVDGVVVLGTTGESPTLTQIEKRRIIEIALEEIQGRIKVIVGTGSYSTQQAIEQTLQAKQMGADAALIVTPYYNKPTQEGIFKHFEAINQAVSFPICLYNIQGRTGQNIQTHTLKRISTLSSIIGVKETSGDINQIMDVIEAFRQSHPNFAILSGDDALTLPMIALGGHGIISVVSNLVPAAMKSLVNAALNGNFKKARIIHNQLYSFIKAAFIETNPIPIKAALSLSKLPAGSCRLPLCDLSQNHSQKLAQILNELPQEWISHG
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTH_YERPY
Sequence: MALVSQARSLGKYFLLFDNLLVVLGFFVVFPLISIRFVDQLGWAALVVGLALGLRQLVQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFALMAMADEPWILWLACALSGLGGTLFDPPRTALVIKLTRPHERGRFYSLLMMQDSAGAVIGALIGSWLLQYDFHFVCWTGAAIFVLAAGWNAWLLPAYRISTVRAPMKEGLMRVLRDRRFVTYVLTLTGYYMLAVQVMLMLPIVVNELAGSPAAVKWMYAIEAALSLTLLYPLARWSEKRFSLEQRLMAGLLIMTLSLFPIGMITHLQTLFMFICFFYMGSILAEPARETLGASLADSRARGSYMGFSRLGLALGGALGYTGGGWMYDTGKTLDMPELPWFLLGIIGLITLAGLYWQFNRRRIESAMLSSS
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPSB_STRPJ
Sequence: MTSIIFSAKDIFEQEFGREVRGYSKVEVDEFLDDVIKDYETYATLVKSLRQEIADLKEELTRKPQVSSAPSPSHPDPIDVAASSSMTNFDILKRLNRLEKEVFGKQILDNTDL
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: SAM_RICCN
Sequence: MNDALKTYLTGIGWFLLSLVSSSANDVISKYLGTRLHSFEVAFFRFFFSSIVLLPFVVYYGKNTLKTSRPFVHILRGLLLFFGMTSWTYGLTIAPVTTATVVSFSIPLFTLILAVFFLNENIIWPRWVVTVVGFIGLVVTLKPHAEDFNPEILYFVLAAISFAMLDIINKKFVIKESMISMLFYSAIVTAIVSLPVASQYWLTPSSFELALLFVLGSSGSLILFFLLKAFSMVDATATAPYRYLELVISVIAAYFIFNEFPDKSTLHGAVIIIPTTLFIIYSEKKAMNRKHESQ
What is the function of this protein?
Transports S-adenosylmethionine.
What are the official names of this protein?
S-adenosylmethionine uptake transporter.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VL1_HPV27
Sequence: MMFMLILMSCSHWTITTQPLAAPWLIPRYLPPLHLHCEGPLQPLSRVVLMCLCILGLILNHPLFLVWGPSFLWLHRCHPLFTYLGGIIIYCQVISCGLNDVNVSTISLQMALWRPNESKVYLPPTPVSKVISTDVYVTRTNVYYHGGSSRLLTVGHPYYSIKKGSNNRLAVPKVSGYQYRVFHVKLPDPNKFGLPDADLYDPDTQRLLWACVGVEVGRGQPLGVGVSGHPYYNRQDDTENAHTLDSAEDGRENISMDYKQTQLFILGCKPSIGEHWSKGTTCNGSSAAGDCPPLQFTNSTIEDGDMVETGFGALDFATLQSNRSDVPLDICTNVCKYPDYLKMAAEPYGDSMFFSLRREQMFTRHFFNRAGKMGDTIPDELYIKSTTISDPGSHVYTSTPSGSMVSSEQQLFNKPYWLRRAQGHNNGMCWGNRIFLTVVDTTRSTNVSLCAAEVSDNTNYKATNFKEYLRHMEEYDLQFIFQLCKITLTPEIMAYIHNMDPQLLEDWNFGVPPPPSASLQDTYRYLQSQAITCQKPTPPKTPTDPYANMTFWDVDLRESFSMDLDQFPLGRKFLLQRGTTPTVSRKRTAVGRGH
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: YQGF_RICRS
Sequence: MIIKNLQEFYRLLIPNAPLIAIDYGSKKLGIALSNQELSIAMPLNTITEINTKIVITVLLNIIEKYKVCGVIIGLPIDMSGAVTEQTNIVMKFAEELAKSINLPIYLQDERLTTKAANNLLKSFGVKRKDRNNNDDAVAASMILETVLDSIKNI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG26_BPMD2
Sequence: MPNSAGVEVARISVKVSPNTKEFRRELKTDLEKIERELSADVPVNADLNAAQAKADFKRLMMQLKTEAARGVNIPVDVNVDKDTKGGFLSRLLGGKKGLSSLGDDAAKASSQVQHLGKSFLDLTRTAWIGVGIVAIAAPLVGLVAGLLAGLPSLLSAFGAGAGVVALGMDGIKAAAETMMPALEAAKTAVSSTFQTGLTPVFQQLGGLLTTLTPNLQNVATGIVNIAKGFTDVVSQGPGLQQLQNILDRTGEFFTGLGPVISTGTQAFLTLSNAGANAFGHLLAPLQEFANGFNDMVNRVTSNGVFDGAMQGLSQTLGSILNLFNRLMESGLQAMGQLGGPLSTLVNGIGDLFIALMPALTSVSSLLGNVLGTLGTQLAPIITALTPAFTTLADTLGTMLTGALQALGPVLTVVAETLGTALTTALQAIQPMLPTLVDSFKQLSETLVTSLGPYLPQIGEAFGQIVGAVIQLAPTIISSLIPAFQTLIPAIAQLAPSLVQIVQAFTKLMPVIVPVVQIVINLAAAVVQAGASIASFLIGGISRLVGVLADCVGAVAEWVGSWSSGVQQVSDFVGQLPGKIKSWFDDAGSWLIEAGKNVVQGLINGIGSMISSAVSKAKELASSVKNAVTGFLGIHSPSRVFAEIGQFTAEGFGNGFEEGFQPVIEKAKALAAELSQAMESGVDPSGILAGISTKELKQYSAALEQERKRIQVEKNAIPKEDKAGRAALQAQLDQIKAQKDILAYQRDRIKNEEDYVGAAGDDPLVKAASGLMNAPVDFAKATGKQFLTDLGISGDGAISKAITEGIQYIFQIGSVDEALSIKDREESKNALSVVGRA
What are the official names of this protein?
Minor tail protein Gp26.
Protein: PO5F1_HUMAN
Sequence: MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3').  Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206.  Critical for early embryogenesis and for embryonic stem cell pluripotency.
What are the official names of this protein?
POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus.
Protein: GPMI_TOBBP
Sequence: GEAVGLPAQQMGNSEVGHLNLGAGRVVHQSLTYINRKIKDGSFFKNKCFLKVIQHVKTNKSKLHLLGLVSDGGVHSHLDHF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: LIPB_BARHE
Sequence: MTFELKYTDRSYLPDQFKAISGNPPVEWKVTNNLVEYPEALRYMQERVENILAQNAHEQVWLLEHPSLYTAGTSAKKKDLLTPHLFPVYEAGRGGEFTYHGPGQRIAYIMLDLKRRRQDIRAFISALEEWIIQMLAKFNIKGERREDRVGVWVQRHSCQSTQNSLYSEDKIAAIGIRVRKWVSFHGVSINVDPNLAHYSGIVPCGITNHGVTSFLDLGLPTKMHDIDIALKQSFEQIFGPIIDIS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER1_STRGO
Sequence: MTMRVSADRTVCVGAGLCALTAPGVFDQDDDGIVTVLTAEPAADDDRRTAREAGHLCPSGAVRVVEDTE
What is the function of this protein?
Electron transport protein for the cytochrome P-450-SU1 system.
What are the official names of this protein?
Ferredoxin-1, Fd-1.
Protein: DDL_COREF
Sequence: MSNSNSAKVRVAVLYGGRSAEHSVSCVSAGAIIAHLDPEKYEVIPVGITTDGAWVVGESDPERLRLVDRTMPEVQRREEIRPSLDPAHRGEFHFADGSLYATADVIFPVLHGRFGEDGTIQGMFALSDIPVVGPGVLSSAAGMDKEFTKKLMAAEGLPIGREVILRDRAELTDAEKKLLGLPVFVKPARGGSSIGISKVSRWEDLPAAVDLARQHDEKVIVESEIVGPEVECGVLQYPDGRIVASLPAMLRGTEDGEGGFYDFDTKYLDNVVTAEIPAPLDEEIIELVQSLAVETFQALACEGLARVDFFVTANGPVLNEINTMPGFTPISMYPQMFAASGVGYEELLDVLVQQALHRSSN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOS7_SCHPO
Sequence: MDQNKSTQATGNGKKTEEINELLESFIKEGPKLLWGSTNLKYEDQISRSSEHELQQYRELFTRLKFSYIEQGTKERYLRAILDDPPMLVEAEDNEKLETTNSSLKGRLKSEKREVDLLTEELKTTSRELSSNYESVMEECKNTKSTLSKLESLESELLKLQQDSSTKTPILPEVEAAIHDLESELNITNESIETIDGKIDNDEKYFIQLTKNLSLLEKEYKIASERSNQIKAAIHTRTPDADAKKQVQNWYTSMLEIYDQLLQK
What is the function of this protein?
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle.  Essential for chromosome segregation and bipolar sister chromatid association.  Required for kinetochore targeting of MIND, but not Ndc80 complex components.
What are the official names of this protein?
Kinetochore protein Sos7, Suppressor of spc7 protein.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore.
Protein: DDA1_XENTR
Sequence: MADFLKGLPVYNESNFSRFHADSVCKASNRRPSVYLPTREYPSDQIIVTEKTNILLRYLHQQWDKKNAAKKRDQDQLEIGETSAPPRKIARTDSQEMSEDT
What is the function of this protein?
Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex.
What are the official names of this protein?
DET1- and DDB1-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDA1 family.
Protein: O164_CONCL
Sequence: MKLTCVLIVAVLILTACQFTAADDMEYPKWLRGLSTDXSERGCWLCLGPNACCRGSVCHDYCPR
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin cal6.4a, Conotoxin cal6.4c.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FPG_NEIMB
Sequence: MPELPEVETTLRGIAPHIEGKTVEAVVLRQLKLRWQINPDLGEILSGRQVLSCGRRAKYLLIRFQTGVLLIHLGMSGSLRIFTPSDGRIGRPDRHDHVDIVFSDGTVMRYRDPRKFGAILWYEGIEEHHPLLEKLGPEPLSEAFCADYLYARLKAQKRAVKLALMDNAVVVGVGNIYANESLFRAGISPHRPANRLKKKECALLVETVKAVLQRAIETGGSTLRDFVDSDGKSGYFQQEYTVYGRHNQPCPRCGGLVVKETLGQRGTFYCPNCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DER_STAES
Sequence: MTKPIVAIVGKPNVGKSTIFNRVVGERISIVEDTPGVTRDRIYSSGEWLTHEFNIIDTGGIEIGDAPFQTQIRAQAEIAIEEADVIIFMVNVREGLTQSDEMVAQMLYKSKKPVVLAVNKVDNLEMRNDIYDFYSLGFGDPYPISGSHGLGLGDLLDAVVENFNKESEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEERVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSEVVLVVIDAEQGIIEQDKRVAGYAHEEGKAIVIVVNKWDTVEKDSKTMKKFTDDVRNEFQFLDYAQIAFVSAKEGLRLKTLFPYINQASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYTTQVAIEPPTFVVFVNDVELMHFSYRRYLENQIRNAFGFEGTPIHIIPRKRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: Y1470_STRP3
Sequence: MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSVRHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS
What are the official names of this protein?
UPF0291 protein SpyM3_1470.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E13B1_PAPLA
Sequence: VPATIPLTITNDSGG
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase 1, (1->3)-beta-glucan endohydrolase 1, (1->3)-beta-glucanase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 64 family.
Protein: ACTP1_ANTAS
Sequence: MSRLIIAFIVVTMVCSAIALPKKKVEPLEKDEKRSLAVAGAVIEGGNLVMSVLDRILEAIGDVNRKIAIGVENQSGKSWTAMNTYFRSGTSDVVLPHSVPSGKALLYDGQKTRGPVATGVVGVFAYAMSDGNTLAVMFSIPYDYNLYSNWWNVKTYSGMKRADQSMYEDLYYHASPFKGDNGWHSRNLGYGLKCRGFMNSSGAAKLEIHVSRA
What is the function of this protein?
Pore-forming protein that forms cation-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers (By similarity).  This protein shows potent hemolytic activity (EC(50)=8. 8 ng/ml) that is specifically inhibited by sphingomyelin.  Shows no phospholipase A2 activity, nor antimicrobial activity against the four bacteria tested.  Is lethal to crayfish (Ref. 1).
What are the official names of this protein?
DELTA-actitoxin-Aas1a, DELTA-AITX-Aas1a, Bandaporin, Cytolysin bp-1.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: DDI1_ASPOR
Sequence: MTVELLKAIVESETSVPPSAQRIVYNNQLLGDDARTLEQVGIGEGDMLGVHVTLRSPQAPTRTAGGPSAPAAQQNLQRRQAMNPDPETIRLHILGDPRVREAVRRQNPELADAASDAQRFRDVFLNQQRREAQLEAEKEARIAMLNADPFNPENQRQIEEIIRQNAVTENLHNAMEHHPESFGRVTMLYIPVEVNGHKLNAFVDSGAQVTIMSPECATACNIMRLVDQRYGGIAKGVGTANILGRVHSAQIKIGSMFLPCSFTVMEGKHIDLLLGLDMLRRHQACIDLRRGALVIQDQAVPFLGEADIPKHLQDGFEDEPLVKGADGAEVGARTGAVTHQAQGPGGASSSTAPPSRPAPAQSSRWPQDSIAKITELGFTREEAMRALDAANGDLDGAIGFLI
What is the function of this protein?
Probable aspartic protease.  May be involved in the regulation of exocytosis.  Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation.  Required for S-phase checkpoint control.
What are the official names of this protein?
DNA damage-inducible protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_SARXA
Sequence: TEGPYFYVPMVNTTGIVRSPYEYPQYYLVNPAAFAILGAYMFFLIIVGFPVNFMTLYVTLEHKKLRTPLNYILLNLAVADLFMVIGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGMISLWSLAVLAIERWVVVCKPISNFRFGENHAIMGVSLTWGMALACTVPPLVGWSRYIPEGMQCSCGIDYYTRAEGFNNETFVLYMFCCHFTVPLTIIFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVVIMVIGFLVCWLPYASVAWFVFTHQGSEFGPLFMTIPAFFAKSSAIYNPMIYICMNKQFRHCMITTLFCGKNPFEGEEEGASSTKTEASSASSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: TF2B_META3
Sequence: MDIKLISKKKNIEERKQLLSELHASKSVIVEKDEELVCPMCDSKNIIKDYEKAEIVCEDCGCVLQDNLFDVGPEWRAFDHEQRVKRSRVGAPMTYTIHDKGLSTVIDWRNKDSYGKDISADKRAQLYRLRKWQRRIRVSDASERNLAFALSELDRIASKLGLPRNVRENAAVLYRGAVEKGLIRGRSIEGVAAAALYAACRRCKVPRTLDEIAEMSRVDRKEIGRTYRFISRELKIRLAPTSPIDYVPRFASELKLPGEVESKAISILQKAGDKGLTSGRGPTGVAAAAIYIASVLHGTRKTQREVADVAGVTEVTIRNRYKELTEHLDIDVTL
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: FAS3_DROME
Sequence: MSRIVFICLAAILTDALTWAQVNVEPNTALLNEGDRTELLCRYGRSINYCRIEIPGEQKVLNLSPEWSKTPGFTYFGAGLTAGQCGVSIERVKASNNGQVKCSLGVEGEELSGTIDLVVALRPQQPIIELLSRPNREGYFNEGTEFRARCSVRDGRPPANISWYIDNMPANKRTTPLEVMSSTNDNVELSTSVQEIQWHLSPEDSNRKLVCRSHHQTDRESVPPQEAAYIINVRYAPVHQPDAAVYGLYLEHTAIVNITIRASPQPKIEWTIDGAIVGQGRTDGRYSAYEPQYLGNDEYNVTLAIAGLTLEDTTKIYNLRASNELGLTDYQVRISSSSKPPSSSLDVAAIVGIVVAVAVLVLVVLLIVFARATGRWCFGGKSIKTPTNETSDTESADIKATSTATATTTMGGVGVSAEEEETVNEQESPQEQQQQQQKKAKRLPAFAAAILRRFNEKDSRKYKDNQESLNIVEGSVQEIPATNNAIDGNDNEPKAIVWQSTSPVWTFK
What is the function of this protein?
Mediates cell adhesion in a Ca(2+)-independent manner.  It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system.
What are the official names of this protein?
Fasciclin-3, Fasciclin III, FAS III.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PT100_HUMAN
Sequence: MGVKLEIFRMIIYLTFPVAMFWVSNQAEWFEDDVIQRKRELWPPEKLQEIEEFKERLRKRREEKLLRDAQQNS
What is the function of this protein?
Plays an essential role in mitochondrial complex IV maturation and assembly.
What are the official names of this protein?
Protein PET100 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PET100 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Mitochondrion. Mitochondrion inner membrane.