PharMolix/UniProtQA huggingface dataset:
Protein: AROL_SHIFL
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAASTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_LACP3
Sequence: MTEQIRIIDAKEHVNEEVKIGAWLTDKRSSGKITFLQLRDGSAYFQGVVSKADVPEEVFSLAKELRQESSMWITGVIHQDSRSHFGYEIEVRNIELVGDSHDYPISPKEHGIEFLLDHRHLWLRSKRQFAIQQIRNEMIRATFEFFNNEGFIKMDPPILTDSAPEGTTELFETDYFDKKAYLSQSGQLYAEAGAMAYGKVFTCGPVFRAEKSKTRRHLTEFWMIEPEMAFCHQEESLKVQERYVAYLVQSVLDNCAYPLHLLDRDPEVLKQYTKLPYPRITYKQAIKMLQDAGMDVKYGDDFGSPEETYLSDQFDQPVFVLNYPKTIKPFYMLTDPEDDQQYVCADMLAPEGYGEIIGGSERETDYDTLKNAIEHAGLDLDEYEWYLDLRKYGSVPHSGFGLGLERAITWVCKLDHLREAIPFPRMINRLKP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR11_ATRBE
Sequence: MAKAIPKISSRRNGRIGSRKGARRIPKGVIHVQASFNNTIVTVTDVRGRVVSWSSAGTSGFKGTRRGTPFAAQTAAANAIRTVVDQGMQRAEVMIKGPGLGRDAALRAIRRSGILLTFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FBPC_NEIGO
Sequence: MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRETTFGLPRTGRCSVPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAVLFIGEGIVFPAALNADGTADCRLGRLPVQSGAPAGTRGTLLIRPEQFSLHPHSAPVVSIHAVVLKTTPKARYTEISLRAGQTVLTLNLPSAPTLSDGISAVLHLDGPALFFPGNTL
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEU3_STRMU
Sequence: MKKIVTLAGDGIGPEIMAAGLEVFDAVAQKINFDYEIEAKAFGGAGIDASGHPLPDDTLAAAKTADAILLAAIGSPQYDKAPVRPEQGLLAIRKELNLFANIRPVRIFDALRHLSPLKAERIAGVDFVVVRELTGGIYFGQHTLTENSACDINEYSASEIRRIMRKAFAIARGRSKKVTSIDKQNVLATSKLWRQIAEEVAKEYSDVTLEHQLVDSAAMVMITNPACFDVVVTENLFGDILSDESSVLPGTLGVMPSASHSESGPSLYEPIHGSAPDIAGKGIANPISMILSVAMMLRDSFGETAGAEMIEHAVNKTLTQGILTRDLGGLANTKQMTAAIIANL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGB1_LVX
Sequence: MEFCGGTLRTRFQRTSVPNSPVTVVHTVAGSGKTTFIRNLLIDHPQLVARTYGTPDVPNLLGYGIRDRHGDAHIVDEYPAADLRSHPSVSIVFADPLQHHGEVRPAHFTCSHTHRFGKSTCSLLGTLGVYCTSDKEDSVTFAGAYLAEPVGTLIALGEDAELVLDNHRVEYFTPCQALGLTFPSVTLLTDAPIEDQPPVSRYIALTRHTDSLLILN
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Increases plasmodesma size exclusion limit.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).
What are the official names of this protein?
Movement and silencing protein TGBp1, 25 kDa protein, Silencing suppressor P25, Triple gene block 1 protein, TGBp1.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp1 protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PLCX3_HUMAN
Sequence: MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESGINIVTADFVELGDFISTVIKLNYVFDEGEANT
What are the official names of this protein?
PI-PLC X domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG8_COCIM
Sequence: MRSKFKDEHPFEKRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDDDGFLYITYSGENTFGN
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: AHPD_ACIC5
Sequence: MPIDTVMETLPGYAKDIKLNYSTLVRQNTELTPQQLWGTVVASAIATRNDTLTAAALEDGAQHLSEQALEAARIAAALMSMNNIFYRFQHLSSNEKYATMPARLRMNGMRTHGVEPVDFELWSLAVSAINGCGKCVDSHEKVLREKGAGEDLVLAAVRVASVIHAIGAVLDAEKVHQPEAAMA
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: PLA3_ORYSI
Sequence: MCCFLLVSVLLATTLTDVASAQRWRQTSGGGKDRWDGLLDPLDADLRRDIIRYGELAQATSDALIGDPASPFAGASRYAPDAFLRKVRASDPDAYRVTRFVYATSSVRLPDAFMPRPAPSAGAAWSGESNWMGYVAVAADGVAANAGRRDIVVAWRGTKRAVEWANDLDITLVPADGVVGPGPGWTQPSVHRGFLSVYTSKSFSSPFNKLSAREQVLAEITRLLRAYKNENCSITITGHSLGAALSTLNAIDIVANGYNVRGSSRVPVPVTAIALASPRVGDDQFKRAFDSTPNLSLLRVRNAPDIVPTILPSAFFKDVGAELLVDTRRSPYLKNPAGPAQWHNLECYLHAVAGTQGAGDGAGFSLVVDRDLALVNKEVDALRDEYQVPAAWWVEKNKGMVQNASGRWVLQDHEEGNLAM
What is the function of this protein?
Acylhydrolase that catalyzes the hydrolysis of phospholipids at the sn-1 position.
What are the official names of this protein?
Phospholipase A1-II 3.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_SYNJA
Sequence: MTLMVRVITPDRTVWDAPAEEVILPATSGQLGILTNHAPLLTAIGNGVMRVKAGGKWSAIAVMGGFAEVENNEVTVLVNRAERGEKVDKAAAQALLDKASQVLNTSSDKQERLQAKLDQQRARALIQAAEMGHKS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: FETP_SALPK
Sequence: MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: GUN1_SCLSC
Sequence: AXSGKLQWIGASESGAEFGQGNLPGVVGTDYTFP
What are the official names of this protein?
Endoglucanase 1, EG1, Cellulase, Endo-1,4-beta-glucanase.
Protein: MP2K3_XENLA
Sequence: GKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINKEGQVNMCDFGISGYLVDSVAKTMDAGCK
What is the function of this protein?
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases.
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, MAPK-ERK kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: SURA_YERPE
Sequence: MKNWRTLILGLVICANTAFAAPQEVDKVAAVVDNGVVLQSDIDGLLQSVKMNAQQSGQQVPDDSTLRHQILERLIMDNIQLQMAKKMGITITDQALDKAIADIAAQNRMTLAQMRSRLAADGLSYDTYREQIRKEMLTSEVRNNEVRRRITILPQEVESLAKQMGNQVSGDTELNLSHILIPLPENPTQQQVDQAEDLANKLVADIKGGADFGKLAIANSADSQALKGGQMGWGKLQELPSLFAERLQSAHKGEIVGPIRSGVGFHILKVNDMRGADQTISVTEVNARHILLKPSPMMTDEQARAKLEAAAAEIKSGKTSFATIAKEISQDPGSAMQGGELGWASPDIYDPAFRDALMKLKKGEISAPVHSSFGWHLIQLVDTRQVDKTDAAQKERAYRMLFNRKFAEEAQTWMQEQRAAAYVKILDGSNAQPQ
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: RNH_EHRRG
Sequence: MKDELNKVVVYTDGACSGNPGPGGWGAVLLFDNGEKTICGGHPNTTNNRMELTAVVQALKFLDVTYVIDLYTDSVYVKSGITSWIKKWKINGWRTADKLPVKNLELWLELDKIVKYHKITWYWVKAHSGNLYNEKADMLARSQIVK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_ESCF3
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GRPE_CORGL
Sequence: MTTPNGMPDNPGDPENTDPEATSADRAEQAAEEAAARQAEESPFGQASEEEISPELEAEINDLLSDVDPDLDGDGEVSAVETQLAERTEDLQRVTAEYANYRRRTERERQGIIDTARAGVVTQLLPLLDDLDLAEQHGDLNEGPLKSLSDKLINILGGLKVESFGEIGEAFDPEIHEAVQDLSQGDVKVLGTVLRKGYRLGDRVIRTAMVLIGDPEES
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAR6B_MOUSE
Sequence: MNRGHRHGASSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIRKKNMLSNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSSQSTDNSLLGFPQQVEASFEPEDQDSDEDDIIIEDSGEPQQIPKATPAQSLESLTQIELSFESGQNGFSPPQDTSLVPVPGSLDTELESRAPDQKLLEEDGTIITL
What is the function of this protein?
Adapter protein involved in asymmetrical cell division and cell polarization processes.  Probably involved in formation of epithelial tight junctions.  Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly.  The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
What are the official names of this protein?
Partitioning defective 6 homolog beta, PAR-6 beta, PAR-6B.
What is the protein family that this protein belongs to?
Belongs to the PAR6 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cell junction, tight junction. Note=Colocalizes with active form of CDC42 or RAC1 at membrane ruffles. Also localizes to tight junctions.
Protein: PVK2_DERKE
Sequence: GGSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.1, PVK-2.1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EPSM_BACSU
Sequence: MKNVAIVGDGGHGKVIRELINARSDTRLAAVLDDKFKTFEGGKEWYTGPPKAVTELRRLIPDVLFLIAVGNNSVRKQLAERLGLGKDDFITLIHPSAIVSKSAVIGEGTVIMAGAIIQADARIGAHCIINTGAVAEHDNQISDYVHLSPRATLSGAVSVQEGAHVGTGASVIPQIIIGAWSIVGAGSAVIRSIPDRVTAAGAPARIISSIQTSNKG
What is the function of this protein?
Catalyzes the conversion of UDP-2,4,6-trideoxy-2-acetamido-4-amino glucose to UDP-2,4,6-trideoxy-2,4-diacetamido glucose, commonly known as UDP-N,N'-diacetylbacillosamine (UDP-diNAcBac).
What are the official names of this protein?
UDP-N-acetylbacillosamine N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: HOG2_ZYGRO
Sequence: MATHEEFIRTQVFGTVFEITNRYTDLNPVGMGAFGLVCSATDTLVGQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFSEMIEGKPLFPGKDHVHQFSIITDLLGSPPRDVINTICSENTLKFVTSLPHRDPVPFQERFKTVEPDAVDLLRRMLVFVPKKRITAADALVHPYLAPYHDPTDEPTAEAQFDWDFNDADLPVDTWRVMMYSEILDFHKIGGGDGQIDTNAAFDDQVAAAHAAAMAQHHHQTQQQSSGKHTNPTTSSSAATITVTVPIAITMPSLIMVIKRFTT
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes.
What are the official names of this protein?
Mitogen-activated protein kinase HOG2, MAP kinase HOG2, ZrHOG2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AGK_XENLA
Sequence: MARVVRIFKTLRNHWKKSTVGFCLLAYGSHWLYGKHCDNLLRRAACEEAQVFGNHQILPHSAIKKATVFLNPAACKGKARTLFEKNAAPVLHLAGIDITVVKTDYEGQAKKLLELMEKTDLIIVAGGDGTVQEVITGLLRRDDEASFSKIPIGFIPLGGTNTLSHTLYPERENKVEQITEATLSILKGETVPLDVLQIKGEQDQPVFAVQGIRWGSYRDASVKVSKYWYLGPLKARAAHLFSALKEWPQQHQASISYLGPAERPPEEPEQKPSRPPLYVRIYRRLALYWSPPKVEVPVEPTPEPWEEAQLSAVELSITTQNHQPDLLRTLDSMSIHIEPDTISKGKFIQLGAQKMTDPLLHPEDSQVLLASRCSLHLPQGTEGHFSIDSEEYEAMSVDVTLLPRKLHFLCHPTRKQELLQSPTATAQS
What is the function of this protein?
Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively (By similarity).  Phosphorylates ceramide but not sphingosine (By similarity).  Phosphorylates 1,2-dioleoylglycerol more rapidly than 2,3-dioleoylglycerol (By similarity).  Independently of its lipid kinase activity, acts as a component of the TIM22 complex (By similarity).  The TIM22 complex mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane by forming a twin-pore translocase that uses the membrane potential as the external driving force (By similarity).
What are the official names of this protein?
Acylglycerol kinase, mitochondrial, Multiple substrate lipid kinase, MuLK, Multi-substrate lipid kinase.
What is the protein family that this protein belongs to?
Belongs to the AGK family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space. Note=Localizes in the mitochondrion intermembrane space, where it associates with the inner membrane. It is unclear whether the N-terminal hydrophobic region forms a transmembrane region or associates with the membrane without crossing it.
Protein: HLY4_AERSA
Sequence: MLASLQSEQGLVYLNASSWLDEQQAAKALTRDQLRERVLGQGERIFIDFSGITDKAEPEQARKAMEQLAGISFDADWVLVSAYKGELLFTPLGPPDDPAFYQVMERIDTLAGQGKRHKRSLTQTATAEAGLPRGAFYLKLNRKISVAECTFPRSRTWDRGDRLFCDSPNISLVYRVNLERSLQFGNTGSATPDAKIVRISLDDESAGGGIQLNEDLTWSENIADYLLLDGWARDYATDAIAQDYRFTIDASNTKAAVLKSLPTNLNSKYEHRRISGFEVGVTGGVEVNKDGPKASWRRRPSSASSVTMPTTPRIIGSNARPECPEGEFQLGAGSIRDGGVTALLQDRHRLGNGVRCGSQPHPAAELQGLRAESGCHLQGGADETGSTEFKIDSSVNIRPIYTGIYKHYYVVGGHVSFQGFEDVDKRRRVTASTSFKVDWNHPVFTGGRPVNLQLGGFDNRCLSAGAEHGLSAVTCDETSAAQSFIYDQYGRYVSALDTRRCLDGNNLGQLQSCRLSLGQRWEWKADSDALSNLSAHQLLGHNKQTGELALYDENGNPADVSVRTLTSYTRILRATAGN
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.
What are the official names of this protein?
Hemolysin 4.
What is the protein family that this protein belongs to?
Belongs to the HlyA hemolysin family.
Protein: MNTP_ECOL6
Sequence: MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ETT1_SCHPO
Sequence: MIGRRPQGLRAAASLKKQQQLEKQKQEASYELSGNSSPSKENGSENVDNGEMEDETMLVYTEEDNISQLWGLYEMSREKLENDDIDASVSLVFGTIHEADRILRNTEDISTLPKDFHAAYSSALLAVSELFEIAQKRLKETNTEESYIDAAIERAQLGLDAPGNESRLFLALARAYLEKVRVLVWRHDNEESLANIPVTQLVNPYIEKAIQYLRPLAQDSTEYFDALTPDSLRPLYILSSYLFQFGDQFSEAFLLDVCSIITALWLKSVVDPNTPAYYKLIAQEAVLNNYTTFAEYYMDLLDNSESNVDDLINKASSWLNNSVDTWNVIYTLDKSPERLLKLADIKMDLAQIVQDEASQDNYLKEACNAIKEAQGSGVELSPDYVEFVEAYSA
What is the function of this protein?
Required for correct translation termination (By similarity).  Positive regulator of the stability of the N-terminal transcription factor domain (Sre1N) of sre1 which is released from the membrane and enters the nucleus to activate hypoxic gene expression.  Acts also as a direct inhibitor of ofd1.  Functions probably by inhibiting the ability of the ofd1 to accelerate Sre1N degradation in absence of oxygen.
What are the official names of this protein?
Negative regulator of ofd1.
What is the protein family that this protein belongs to?
Belongs to the ETT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: USB1_DANRE
Sequence: MIVNYSSSSSEEESGSSSSPSGKRQKLDTETSEALDHGSAQRKVCKSSHLTPRLPLPESVKEMFRDSEELWTDKSEEHGGRLRSFQHERGNWATYVFFPYDPEEAFLEVLNKMMAAAEAHDIPLTVSEEFHLSLSKTVVLRHHWIQPFVQSIRTSLTHFQKFYCVAYKLKVYSNAEKTRTFLGMEVSTGTPHLLELSKIVDETMKEFNLSTFYEDPSFHISLAWCVGDQTERLKKACLLELQGLIDAHEDGPFHARLNCNELRCKTGNKVFVFPLQ
What is the function of this protein?
3'-5' RNA exonuclease that trims the 3' end of oligo(U) and oligo(A) tracts of the pre-U6 small nuclear RNA (snRNA) molecule, leading to the formation of a mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.  Participates in the U6 snRNA 3' end processing that prevents U6 snRNA degradation.  In addition also removes uridines from the 3' end of U6atac snRNA and possibly the vault RNA VTRNA1-1.
What are the official names of this protein?
U6 snRNA phosphodiesterase 1, 3'-5' RNA exonuclease USB1.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. USB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAO1B_XENLA
Sequence: MPSTSRAGSLKDPDVAELFFRDDPEKLFSDLREIGHGSFGAVYFAHDARTSEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQRIQHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEIEIAAITHGALQGLAYLHSHNLIHRDIKAGNILLTEPGQVKLADFGSASIVSPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCVELAERKPPLFNMNAMSALYHIAQNESPTLQSTEWSDYFRNFVDSCLHKIPQDRPTSDELLKHMFVLRERPETVLIDLIQRTKDAVRELDNLQYRKMKKLLFQEAHNGPAVETQEEDEEQEHGVGRTGTVNSIGSNQSIPSMSISASSQSSSVNSLPDASDDKSELDMMEGDHTVMSNSSVIHLKPEEENYPEEPDPRTRPSEPQSPPQVSRHKSHYRNREHFATIRTASLVTRQIQEHEQDSELREQMSGYKRMRRQHQKQLMALENKLKAEMDEHRLRLDKDLETQRNNFAAEIEKLVKKHQAAMEKELKLMANEEKKFQQHIQAQQKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENFQHFQAEEEANLLRRQRQYLELECRRFKRRMLLSRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESMQELEFRHLNTIQRMRCELIKLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLKSTPKNEHKAVLKRLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHEREIRELEQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMILSNLSPEAFSHSYPGASGWSHNPTGGPGPHWGHPMAGPPQAWGHPMQGGPQPWGHPSGSVQGVSRGSTMGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT
What is the function of this protein?
Serine/threonine-protein kinase involved in various processes such as p38/mapk14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability.  Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of upstream MAP kinase kinases.  In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase TAO1-B, Thousand and one amino acid protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH3Y1_RAT
Sequence: MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNRKFYCQDIRAYDILFGDVPQPAQAEDLYEILNSFTEKYETEGQRINLKKVAREQRKAKELPPKPSSRPQPSRPPVQLNAGSQSNRNEYKLYPELSSYHEKTGSLSQPIEVTALYSFEGQQPGDLNFQAGDRIIVISKTDSNFDWWEGKLRGQTGIFPANYVTMN
What are the official names of this protein?
SH3 domain-containing YSC84-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SH3YL1 family.