PharMolix/UniProtQA huggingface dataset:
Protein: YTEP_BACSU
Sequence: MKTAEAQAPAVDAVIFKKEKRKRLLIKLIQQKYLYLMILPGCIYFLLFKYVPMWGIVIAFQDYQPFLGILGSEWVGLKHFIRLFTEPTFFLLLKNTLVLFALNLAIFFPVPILLALLLNEVRIALFKKFVQTLIYIPHFMSWVIVVSLSFVLLTVDGGLINELIVFFGGEKINFLLNEEWFRPLYILQVIWREAGWSTIIYLAAITAVDPQLYEAAKMDGAGRLRQMWHITLPAIKSVIVVLLILKIGDTLELGFEHVYLLLNATNREVAEIFDTYVYTAGLKQGQFSYSTAVGVFKAAVGLILVMLANRLAKKFGEEGIY
What is the function of this protein?
Involved in pectin degradation (PubMed:29240795).  Part of the ABC transporter complex YtcQP-YteP involved in the uptake of polygalacturonan and rhamnogalacturonan type I (PubMed:17449691, PubMed:29240795).  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Polygalacturonan/rhamnogalacturonan transport system permease protein YteP.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTH_ECOLC
Sequence: MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEELMDMIVLGQVERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFTSALLARHFLIQ
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_OPITP
Sequence: MKIGFLGGSFDPVHFGHLIAAQDAFEQFRLDRLILVPAAQAPLKPNDVQSSPEDRFAMLRAAVEWDQRFEVSDVELRRGGTSYTIDSARYFRKQFPRDELYWIIGGDQLPQLHLWRDVSELGQLVDFIFLERPGFPIKARVDIPGLRLHRCDGHLLAISSTELRDRVKRNLSLDYFVPHKAIVYIREKHLYRPSQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RL9_BORGP
Sequence: MKVILKEDFTNLGREGDTVEVKDGFARNYLLPKGFAVFSNKHNVEIFNQKKRSILKKQETKKQIANDLKSKLDLVKLEFFMKSNDSGKLFHSINSLNIAEELLKLGFDIERKKIDIHHGTLKAFGTYDVTVKLYEGISAIIKVEIKKEKKQEDKKSLNKKLNKVDE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RNC_IDILO
Sequence: MSLPKPPLTELEKIVGYSFEQQGLLHQAMTHRSASSTHNERLEFLGDSILGLVIAEALYQKFPKVAEGDLSRMRAAIVCGRSLAKLGKKMGLGDFLSLGQGELKSGGYRRESILADAVEAIIGAIYLDSDMDTIRQVILNWFEPQLTLIEPGTSQKDPKTRLQELLQARQKPLPEYDVVATQGQAHNQQFTVNCSVEGIESPFKGTGTSRRKAEQAAATAALEHLQESA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_BARQU
Sequence: MATFSQKPTEVVKKWVIIDAENLVLGRLAAFVANRLRGKHKATFTPHVDDGDNVIVINADKIVLTGKKYTDKKYYWHTGYIGGIKERTARQILEGRFPERVVEKAVERMIPRGPLGRRQLRNLHVYAGSQNPHAAQQPEALDVGALNRKNKRIA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CBPO_BOVIN
Sequence: MKPLLGTFYLLGMLVPGWLGYDRSLTQQRQEVVDKVVSPWSILETYSYNRYHPMGEIYQWMSEIREKYTEVVTQHFLGMTYESRPMYYLKISQPSSNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNYEDNSRIRRLLKNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSSHNNGTCFGTDLNRNFDASWCSIGASHNCESLTFCGTGPMSEPETKAVSSFIESKKENIACFLTMHSYGQLILVPYGYTKNKSNNHEELIQVGQKAANALKAKHGTNYRVGSSADILYATSGSSRDWARDIGIPFSYTFELRDNGTYGFVLPETQIQATCEETMEAVLSVLDDVYEKYWYTNSARKAKSTALVLGLLMSFMSLL
What is the function of this protein?
Carboxypeptidase which preferentially cleaves C-terminal acidic residues from peptides and proteins.  Can also cleave C-terminal hydrophobic amino acids, with a preference for small residues over large residues.
What are the official names of this protein?
Carboxypeptidase O, CPO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor, GPI-anchor.
Protein: FTHS_RENSM
Sequence: MTSTTEPMTDLHIAQQAVLHPIFDIADAAGIPEEALEQYGRYKAKVDVRKVPDSGRAGRVVLVTAVSPTPAGEGKSTTTVGLADSLNRAFEQEGTGRRSMIALREPSLGPTLGMKGGATGGGYSQVLPMDEINLHFTGDLHAINSANNALCALIDNHIYQGNVLNIDPRRITFKRVLDMNDRALREVVIGLGGPTQGVPRQDGFDITVASEIMAVFCLATDLNDLKSRIGKITFGYNYDRQPLTVAGLGVEGVLTLLLKEAIKPNLVQTLAGTAALVHGGPFANIAHGCNSVIATSLARRRADVVVTEAGFGADLGAEKYMDIKSRFADVAPSAVVIVATIRALKMHGGVPKTELSVSDVAALRRGVTNLARHISNVRQFGLDPVVSINRFTSDSEEELDWLVSWCESQGVSIAIADVWGRGGGGDDLAAKVLAALDAPSDFRHLYELELPVKEKIELIAQKIYGAERVEFSSSALKRIAEISANGWDSLPVCMAKTQYSFSDDASLLGAPSGFVLHVRDLVPKTGAGFIVALTGAVMTMPGLPKQPAALKMDVDAEGNSVGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: GREA_RICPR
Sequence: MNTKFPITAKGFKKLEHELKHLKHVERKKISEDIAEAREHGDLSENAEYEAAREKQAFIEGRIKELEDMTARAEIIDICKLSGDNIKFGATVTLIDDDTEEEVTYIIVGEYEADITKKRVSIASPIAKALIGKSVGDFVEVTTPKGLKSYEVVTVEYKELDL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: US33A_HCMVM
Sequence: MSLRFPERAGYEKLGYRPHAKRVWVHDPLGLTRFIMRQLMMYPLVLPFTFPFYVPRS
What are the official names of this protein?
Uncharacterized protein US33A.
Protein: SOMA_ESOLU
Sequence: MGQVFLLMPVLLVAGYLSLGAAMENQRLFNIAVNRVQHLHLLAQKMFNDFEGTLLPDERRQLNKIFLLDFCNSDSIVSPIDKHETQKSSVLKLLHISFRLIESWEYPSQTLTHTMSNNLNQNQMSEKLSNLKVGINLLIKGNQEDVPSLDDNDSQQLLPYGNYYQNLGDNDNVRRNYELLACFKKDMHKVETYLTVAKCRKSLEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMO_ECO7I
Sequence: MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPI1_BRUME
Sequence: MSFIRSALAAAAFVALSIGAVQTASAADPENTVILKLKDGDVALELRPDLAPKHVAQIKKLVREGAYNGVAFHRVIPGFMAQTGDVKFGNMDKGFDAARVGTGGSNYPDLPAEFSKEPFVRGTVGMARSQNPNSANSQFFIMFDDGPFLNGQYTVVGKVVSGMDAVDKIKKGSEAENGAVKNPDKIIKATIEADTK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Probable peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CH60_STRTD
Sequence: MAKDIKFSSDARAAMVRGVDTLADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPIGIRRGIEAAVAAAVEELKVIAQPVANKEAIAQVAAVSSRSEKVGEYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPYILVTDKKISNIQDILPLLEEVLKTSRPLLIIADDVAGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAVLTGATVITEDLGLELKDATMESLGQASKVTVDKDSTVIVEGAGSAEAIANRVNLIKSQLETTTSEFDREKLQERLAKLSGGVAVIKVGAATETALKEMKLRIEDALNATRAAVEEGIVAGGGTALVNVIAKVAELDLEGDDATGRNIVLRALEEPVRQIAYNAGYEGSVIIDKLKNSPVGTGFNAANGEWVDMVESGIIDPVKVTRSALQNAASVASLILTTEAVVADKPEQKAPAAPATDPGMMGY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHJ_ECO7I
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAVSTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KATG_RHOP5
Sequence: MDAKTDDKDAGKCPFSSGSHAHRNRDWWPDQLDIQVLHHNSKKSDPLGEAFNYAEEFKKLDLAALKQDLTALMTDSQDWWPADFGHYGGLFIRLAWHSAGTYRISDGRGGAGAGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGNKISWADLFVLSGNVALESMGFKTFGFAGGRADTWEPEELYWGPEGTWLGDSRYSGERELSDPLGAVQMGLIYVNPEGPNGNPDPVGSAKDIRETFYRMAMNDEETVALIAGGHTFGKTHGAGDPSLLGPDPEAGALEDQGLGWKSGYGTGFGADAITGGPEVIWSQEPTKWSNHFFENLFNFDYELTKSPAGAQQWVAKNAEPSIPDPFDPSKKRLPTMLTSDLALRFDPIYEKISRRFFENPDQFADAFARAWYKLTHRDMGPVPRYLGPEVPKEVLLWQDPVPAVDHELVSEQDIAALKAKILASGLSVAQLVSAAWASASTFRGSDKRGGANGGRIRLSPQKDWEVNHPAELAQVLSKLEAIQSEFNAQGGGKKVSIADLIVLGGAAAIEKAAQEAGTAVTVPFTPGRTDASQEQTDVESFKPLEPRADGFRNYVSSIRHQFMKPEEALVDKAQLLKLTGPELTVLVGGLRVLGANYGHTTHGVLTDRPERLSNDFFVNLLDMKYAWAPSPTTTGIYEARDRKSGELKWTGTRVDLIFGSHSQLRAFAEVYAQADAKEKFVHDFVAAWTKVMNADRFDIVR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: NQRA_HAEIN
Sequence: MITIKKGLDLPIAGKPAQVIHSGNAVNQVAILGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVIFTAPASGTITAINRGEKRVLQSVVINVEGDEKITFAKYSTEQLNTLSSEQVKQNLIESGLWTALRTRPFSKVPSIESEASSIFVNAMDTNPLAADPSVVLKEYSQDFTNGLTVLSRLFPSKPLHLCKAGDSNIPTADLENLQIHDFTGVHPAGLVGTHIHFIDPVGIQKTVWHINYQDVIAVGKLFTTGELYSERVISLAGPQVKEPRLVRTTIGANLSQLTQNELSAGKNRVISGSVLCGQIAKDSHDYLGRYALQVSVIAEGNEKEFFGWIMPQANKYSVTRTVLGHFSKKLFNFTTSENGGERAMVPIGSYERVMPLDILPTLLLRDLIVGDTDGAQELGCLELDEEDLALCSFVCPGKYEYGSILRQVLDKIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: GTRA_BPSF2
Sequence: MLKLFVKYTSIGVLNTLIHWVVFGVCIYAAHTSQALANFTGFVVAVSFSFFANARFTFKASTTAMRYMYYVGFMGILSVIVGWAADKCSLPPIVTLITFSAISLVCGFVYSKFIVFRDAK
What is the function of this protein?
Involved in O antigen modification.  Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane.
What are the official names of this protein?
Bactoprenol-linked glucose translocase.
What is the protein family that this protein belongs to?
Belongs to the GtrA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HEM1_PSET1
Sequence: MTIIALGINHKTAPVELREKVAFSPEQISEALQQLSGHAHFNEAVIVSTCNRTEVYCSLAQQNSQTLLQWLSSFHGLDEHELSKNIYCHEGSDAINHLMRVACGLDSLVLGEPQILGQIKQAYNSAKTHNAVGVTFDRLFQKTFSVAKQVRTETNIGASAVSVAYAAVNLAKHIYGKLDKTNVLLIGAGETIELVAKHLYQNEPQNITVANRTLERARSLADQVSGDVIALAQLPERLHKADIVISSTASTLPIIGKGVVEQALKQRRYKPMLFIDIAVPRDIESQVGELDDAYLYSVDDLQTIVSENMSAREEAAEQAEVIITERTKEFLMWIRSLDSVDLIRHYRNDVQTIKSELVERAVSQLNTGKDAEKVILELANKLTNRLMHAPTRAIQDAAKKGEVAQLNQLKKMLGIDQE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CRL1_CANAW
Sequence: MTPNGSRRHSAYMGSPRSQHSSTMETGYNPYEAVQKKQELYQNNNGNSPTVIIEEDPYIPNYKESSLANKKTNYNMKIVVVGDGGCGKTCLLLAYTQNKFPSIYVPTVFENYVTAVQSPNGKTVELALWDTAGQEEYDRLRPLSYPDVDILLVCFAVDNEVSLENVKDMWFPEVNHYCPGIPIILVGTKSDLSSDMNHDASIRVAKEIGAIGLIFTSAKTMFNVRTVFNFALNHFQRNMELQEQYEKTLGSRKRISRVLGGSNGGSGNHSRHHSRNYSNVSNNRRGHLKNTSYDSTALLDQPLTEDTYVKNPYGNFGYKANVESPYNQDEFAFTRERKKKKKCVIL
What are the official names of this protein?
GTP-binding RHO-like protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: CAPSD_HEVMY
Sequence: MRPRPILLLLLMFLPMLPAPPPGQPSGRRRGRRSGGSGGGFWGDRVDSQPFAIPYIHPTNPFAPDVTAAAGAGPRVRQPARPLGSAWRDQAQRPAVASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRAAILRRQYNLSTSPLTSSVATGTNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVVRATIRYRPLVPNAVGGYAISISFWPQTTTTPTSVDMNSITSTDVRILVQPGIASELVIPSERLHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSPVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRVSRYSSTARHRLRRGADGTAELTTTAATRFMKDLYFTSTNGVGEIGRGIALTLFNLADTLLGGLPTELISSAGGQLFYSRPVVSAHGEPTVKLYTSVENAQQDKGIAIPHDIDLGESRVVIQDYDNQHEQDRPTPSPAPSRPFSVLRANDVLWLSLTAAEYDQSTYGSSTAPVYVSDSVTLVNVATGAQAVARSLDWTKVTLDGRPLSTIQQYPKTFFVLPLRGKLSFWEAGTTKAGYPYNYNTTASDQLLVENAAGHRVAISTYTTSLGAGPVSISAVAVLAPHSALALLEDTLDYPACAHTFDDFCPECRPLGLQGCAFQSTVAELQRLKMKVGKTREL
What is the function of this protein?
Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter.  The capsid is composed of 60 copies linked to each other.  Binds to the 5' end of the genomic RNA to mediate genome encapsidation (By similarity).  Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry.  Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes (By similarity).  Inhibits IFN production by blocking host TBK1-induced IRF3 phosphorylation (By similarity).  The nuclear form probably modulates host gene expression (By similarity).
What are the official names of this protein?
Pro-secreted protein ORF2, Protein ORF2, pORF2.
What is the protein family that this protein belongs to?
Belongs to the hepevirus capsid protein family.
What are the subcellular locations of this protein?
[Isoform Secreted protein ORF2]: Secreted. SUBCELLULAR LOCATION: [Isoform Capsid protein ORF2]: Virion. Host cytoplasm. Host endoplasmic reticulum. Host Golgi apparatus. Host cell surface.
Protein: RUVC_BORT9
Sequence: MIMRILGIDPGLANVGWGILDRKGSKYMYVQDGTVITHPFMSLKDRLKLISDEIILIIDNFKPDVASIENIYFAKNKKTAISVSEARGAIILTFALKNLDFYEYTPIQVKNSISGFGRIEKVQVKYVIRILLGMKPDFIFTSDHSSDALALAICHGNYHIL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CAPP_ECO27
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQLDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVRIDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDVYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKELRNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGQEPDPRVEQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: PAU18_YEAST
Sequence: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSTRLKPAISKALSKDGIYTIAN
What are the official names of this protein?
Seripauperin-18.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
Protein: YMX1_RAPSA
Sequence: MITFFEKLSTFCHNLTPTECKVSVISFFLLAFLLMAHIWLSWFSNNQHCLRTMRHLEKLKIPYEFQYGWLGVKITIKSNVPNDEVTKKVSPIIKGEIEGKEEKKEGKGEIEGKEEKKEGKGEIEGKEEKKEVENGPRK
What is the function of this protein?
Involved in cytoplasmic male sterility (CMS) by leading to pollen abortion.  Not expressed in fertile (normal) plants.
What are the official names of this protein?
Uncharacterized mitochondrial protein ORF138.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: DAPB_BURO1
Sequence: MKIAIAGASGRMGRMLIEAVLNDADAQLVGALDRAGSPFLGQDAGAFLGKDTGVKLTDDLDAVFAQAEYLIDFTRPEGTMAHIEAALRHDVKLVIGTTGFTAEQKADLQAAAARIGIVFAANMSVGVNVTLKLLEFAAQHFSHGYDIEIIEAHHRHKVDAPSGTALMMGEAVAGALGRSLDDCAVYGRHGVTGERDPSSIGFAAVRGGDIVGDHTVLFAGIGERIEITHKSSSRVSYAQGALRAVRFLSARGAGLFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
Protein: CUL3_DICDI
Sequence: MMAKPNGKIQFKNLQSHGVLADPDFPKRTWKLLKTAMRQIHQQNASNLSFEELYRNGYNMVLQKHGDLLYNNLKKMVDKHLKAVAKTVSESIDEKFLLELNSSWINHKTSMLMIRDILMYMDRNYVKQNNLSSVFDLGLYLFRDNVAHCSTIKDRLLNTLLSMVQKEREGEVIDRILIKNIVQMLIDLGVNSKNVYIEDFEKPLLLKTSSHYQAQSQTLIQTCSCPDYMKKVEICLKEELERVSHYLDSSSEPKLKEVCEKQLISNHMRTLIDMENSGLISMLKDDKIEDLKRMYNLFSRVSDGLNLMKDVISSYVKEIGRGIVMDEEKTKESGTYFQSLLDLKDKYDNLLQNALYNDKQFIHSIQQAFEYFINLNPKSPEYISLFIDEKLKKGLKGVSEEEVDIILDKILMLFRLIQEKDVFEKYYKQHLAKRLLLGRSISDDAERNMIAKLKTECGYQFTSKLEGMFTDMRLSQDTMSGFKTYIQNLKKALPIDLNVHVLTTGFWPTQNTANCNLPREILLCCEAFKSYYLSNHNGRLLLWQTNMGTAEIKANFPSKSHELQVSSYQMVILLLFNDQSKLTFKEIADQTGIPTIDLKRNLLALTNPKNKILDRELPSTTSSTTTTTTTATSSSTSTSPSSSSSSISTPTPSKSIDESDVFAFNTKFKSKLFRVKVMAVVQKETPVEEKETRDKVDEDRKHQIEASIVRIMKARKTLEHSNLVSEVIKQLQSRFVPNPVIVKKRIESLIEREYLERSKQDRKIYNYMA
What is the function of this protein?
Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity).
What are the official names of this protein?
Cullin-3, CUL-3, Cullin-C.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL18_SALNS
Sequence: MDKKSARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ENGB_HAHCH
Sequence: MTQTTKRPVSYQSARFLMSAEQLQQCPPDVGVEVAFAGRSNAGKSSALNAITQNGKLAKTSKTPGRTQLINFFTLNSEGCRLVDLPGYGYAKVPKAMLEKWRSNLQRYLEHRLTLNALILVMDIRHPLSPFDCSMLDWCEARDLPTLVLLTKADKLKYGPAKTTLQEVKKELKQKWRFPVEAQLFSSVSKVGVEEAHAFMDRFFIPPDETTSDVETTEEPQA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RIMP_BACC3
Sequence: MDKKVTEVVEAFAQPIVEELNLELVDVEYVKEGQDWFLRVFIDSEKGVDIEECGAVSERLSEALDKEDPIPHLYFLDVSSPGAERPLKKEKDFQQAVGKQVAIKTYEPIDGEKMFEGKMLSYDGTTITLLLTIKTRKKEIQIPMDKVANARLAVTF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.