PharMolix/UniProtQA huggingface dataset:
Protein: EFP_SALPA
Sequence: MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_BRAHW
Sequence: MAKKVVGIVKVRIPGGEATPAPPLGPALGQKQIQIAAFVKDFNAKTSKMKGQLLNTYITVYEDKTYTFVTKGTSTSTLIKKKLGIEKGSGEPNKTKVATINQKQLEEIAQEKMAYMSANDIEAAKKIVAGTARAMGIKVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: WRK10_ARATH
Sequence: MSDFDENFIEMTSYWAPPSSPSPRTILAMLEQTDNGLNPISEIFPQESLPRDHTDQSGQRSGLRERLAARVGFNLPTLNTEENMSPLDAFFRSSNVPNSPVVAISPGFSPSALLHTPNMVSDSSQIIPPSSATNYGPLEMVETSGEDNAAMMMFNNDLPYQPYNVDLPSLEVFDDIATEESFYIPSYEPHVDPIGTPLVTSFESELVDDAHTDIISIEDSESEDGNKDDDDEDFQYEDEDEDQYDQDQDVDEDEEEEKDEDNVALDDPQPPPPKRRRYEVSNMIGATRTSKTQRIILQMESDEDNPNDGYRWRKYGQKVVKGNPNPRSYFKCTNIECRVKKHVERGADNIKLVVTTYDGIHNHPSPPARRSNSSSRNRSAGATIPQNQNDRTSRLGRAPPTPTPPTPPPSSYTPEEMRPFSSLATEIDLTEVYMTGISMLPNIPVYENSGFMYQNDEPTMNAMPDGSDVYDGIMERLYFKFGVDM
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).  Modulates seed size by negatively regulating the cellularization of syncytial endosperm (PubMed:16293693).
What are the official names of this protein?
Probable WRKY transcription factor 10, Protein MINISEED 3, WRKY DNA-binding protein 10.
What is the protein family that this protein belongs to?
Belongs to the WRKY group I family.
Protein: TTC36_DROME
Sequence: MPQANLTLSPHDQQVLDSIFNPLELSSLQTNNLIPAESDLKDEEPDTQAIKASRELELKAIALSESGELDGALELFQQSLNLAQRASVLNNRAQTLRLAKRDEEALDDLNKALELANDQQTRTKCHAHCQRGVLYRKLDNLEAARADFEAAAQLGSKFAREQLVEINPYAALCNQMLRQAFDQLK
What are the official names of this protein?
Tetratricopeptide repeat protein 36 homolog, TPR repeat protein 36 homolog.
What is the protein family that this protein belongs to?
Belongs to the TTC36 family.
Protein: UB72_DEIRA
Sequence: MFERDEHHFPVKRLLLLGALVGAGAYYLSREQNRKALDAKLAELGLKDAAQDVGSSVTKGWEKTKDAAQNAGSVIADKAQDVAGEVKSAVAGATAEIKDAGKEVADTAKDAGQNVGQNVKREAADLADQAKDKAQDVKADVSKAADQAKDKAQDVAQNVQAGAQQAAANVKDKVQDVKADASKAADQAKDKAQDVAQNVKQGAQQAASDAKDKVQDVKADASRAADQAKDKAQDVAQNVKQSAQDAKTDVDAKAKSWAFDLRTDAEAGKQGGQTGSTTNNAGTAGNTGMTGNTNTRKN
What are the official names of this protein?
Protein DR_1172.
What is the protein family that this protein belongs to?
Belongs to the LEA type 1 family.
Protein: HSLO_LACJO
Sequence: MKDYLVKAIDKTKNLRLITVDAKDLVSEAQKRHDTWSASSAVLGRTLIGGLLLSAALLKDKDELTVRLLGNGPVGATIVTAKADLTIKGYIQNPHIALPPKKDGHIDVAKAVGKDWLEVTKDQGLKEPYTGQVPIVSGEIAEDFTYYLAKSEQIPSAVGLSVFVEPNNEIGAAGGFILQALPGATDEQLAEVEKRIKALPNLSTLFLDGMTPENLAERILGTDCKILAKEDVSFACDCSKEKYSQILATLKPAQLKEMIEKDHGAELVCRFCKEKYHFTEDELKDVLKKAN
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_STAS1
Sequence: MDYKDIATPTRTKALLNQYGFNFKKSLGQNFLIDVNIIHNIIDASDIDEQTGIIEVGPGMGSLTEQLAKSAKKVMAFEIDQRLIPVLKDTMRPYDNVTVINEDILKADIAHYITEHLTDCEKIMVVANLPYYITTPILLNLMQQKLPIDGYVVMMQKEVGERLNAQVGTKAYGSLSIVAQYYTETSKVLTVPKSVFLPPPNVDSIVVKLMKRPTPIVDIDDENKFFKMTKAAFSQRRKTINNNYQSLFVNGKVNKEKILEWLEAAGIDPRRRGETLSIKEFANLYNELQNFTELEF
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_MYCTU
Sequence: MAEQPAGQAGTTDNRDARGDREGRRRDSGRGSRERDGEKSNYLERVVAINRVSKVVKGGRRFSFTALVIVGDGNGMVGVGYGKAKEVPAAIAKGVEEARKSFFRVPLIGGTITHPVQGEAAAGVVLLRPASPGTGVIAGGAARAVLECAGVHDILAKSLGSDNAINVVHATVAALKLLQRPEEVAARRGLPIEDVAPAGMLKARRKSEALAASVLPDRTI
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RSMH_MYCTO
Sequence: MQTRAPWSLPEATLAYFPNARFVSSDRDLGAGAAPGIAASRSTACQTWGGITVADPGSGPTGFGHVPVLAQRCFELLTPALTRYYPDGSQAVLLDATIGAGGHAERFLEGLPGLRLIGLDRDPTALDVARSRLVRFADRLTLVHTRYDCLGAALAESGYAAVGSVDGILFDLGVSSMQLDRAERGFAYATDAPLDMRMDPTTPLTAADIVNTYDEAALADILRRYGEERFARRIAAGIVRRRAKTPFTSTAELVALLYQAIPAPARRVGGHPAKRTFQALRIAVNDELESLRTAVPAALDALAIGGRIAVLAYQSLEDRIVKRVFAEAVASATPAGLPVELPGHEPRFRSLTHGAERASVAEIERNPRSTPVRLRALQRVEHRAQSQQWATEKGDS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_RUEPO
Sequence: MPPAVSVCASSGISVLRKRSDFLKAARARRQGAGSMMVQARKRDAGEAEGIRVGFTCSKKVGNAVARNRAKRRLREAARLVLPDMGRPGWDYVLIGRPSDTASRPFDGLLDDLRRALRKLHAPKP
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: UVRC_BORRA
Sequence: MRKHLNDLYKQIEKFPKTSGCYKMYSKDNKILYIGKAKNLRSRVKNYFSKRTSHKTKILMNNVTNIEIITTNSEYEALLLECNLIKKYKPTYNIKLKDDKGYPMIRITCEKYPRIFKTRKIINDGSEYFGPYVNVKNLDLVLDLINKTFKTKKCKKKSKNPCLYFHMGQCLGVCYREDLEDEYRKEIEQIKHILNGNISKLLNDIEIKMKEVIMKENFEAAIKLKETKKSLIEISQTQIITKIDKLSEDYLYIHKTNSLNTIVILKYKDGKLTEKDIHFDESIYEEDELIEKFITQYYTSPNMIVPDKIHIFKKIDTSNITKLINELKNIKTEIIYKETKDNIKIIEMATSNAKLALITYNHEKNKAIENLKTILEMKKLPKTIEGFDIAHINGYKTVASLVTFKMGKPFKDGYRVYKINSLSNGEIDDCKAIKEVISRRYSKLINEQLKLPDLILIDGGKGQLNSAYSILKGLRIEEKIAICALAKKEEIIFLPNKNQGIKLQKRNSALQVLQNVRDEAHRRANNFNNKLHNNIKLNYTKIKGIGEQKAKKILKVLGTYKDILLLNEDEIATKMKINITMANKIKKFAEEQNLNNKQNNHI
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_AZOVD
Sequence: MAIVKCKPTSAGRRFVVKVVNQELHKGAPYAPLLEKKSKSGGRNNNGRITTRHIGGGHKQHYRLVDFRRNKDGIPATVERIEYDPNRTAHIALLKYADGERRYIIAPKGVVAGDQLISGVNAPIKAGNTLPLRNIPVGSTIHGVELKPGKGAQIARSAGASAQLVAREGAYVTLRLRSGEMRKVLADCRATLGEVSNSEHSLRSLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGFPTKGAKTRSNKRTDNMIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RISB_PROMT
Sequence: MATIEGTFVNSSSLRVAIVIARFNDLITNKLLSGCMDCLSRHGIDVSESSNQLDIAWVPGSFELPIISQKLARNGNYDVVITLGAVIRGDTPHFDVVVSEASKGIATVSRETGVPIIFGVLTTDTMQQALERAGIKNNLGWSYALQALEMGSLMKAVN
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: HLDD_PECAS
Sequence: MIIVTGGAGFIGSNIVKSLNDIGYRDILVVDNLKDGTKFVNLVDLDIADYVDKEDFVASIVAGDDLGDIEAVFHEGACSSTTEWDGKYMMDNNYQYSKDVLHYCLDRSIPFLYASSAATYGGRNDNFIEDRQYEQPLNVYGYSKFLFDQYVREILPEAESQICGFRYFNVYGPREGHKGSMASVAFHLNNQINQGENPKLFSGSENFKRDFIYVGDVAAVNLWFWQNGVSGIFNCGTGRAESFQAVADATLAFHNKGGVEYIEFPEKLKGRYQAYTQADLTNLRAAGYDKPFKTVAEGVAEYMTWLNRTV
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: CARF_RAT
Sequence: MAQEVSEYLSQNPRVAAWVETLRCEGETDKHWRHRREFLLRNAGDLVPATEETADAESGARSRQLQQLVSFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPIHTTRDELVAKVKKRGISSSNEGVEEPSKKRSIEGKNNSSVERDHGKKSAKTDRSAQQENSSGSKGSSTKSESSGTSARSNSGVSHQNSSTSEGDRSVCSQSSSNSSQVTSAGSGKASEPEAPDKHGSASFVSSLLKSSLNSHVTKSTDSRQHSGSPRKNALEGSSVSVSQSSSEIEVPLLGSSGSSEVELPLLSCKSSSETASSGLTTKASSEANISSSVSKNSSSSGTSLLMPKSSSTNTSLLTSQVAASLLASKSSSQSSGSVASKSTSLGSMSQLASKSSSQSSTSQLPSKSTSQSSESSVKFTCRKLTNEDIKQKQPFFNRLYKTVAWKLVAVGGFSPNVNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGNEIEDLVLLDEESRPVNLPPALKHPQELL
What is the function of this protein?
Regulates DNA damage response and cell proliferation in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence.
What are the official names of this protein?
CDKN2A-interacting protein, Collaborator of ARF.
What is the protein family that this protein belongs to?
Belongs to the CARF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: RL20_METC4
Sequence: MARVKRGVTSHAKHKKVLKAAKGYYGRRKNTIRIAKQAVEKGLQYAYRDRKNKKRTFRALWIQRLNAAVREHGLTYSRFINALAQSGIEVDRKALSELAIHEPAAFAAVVAKAKSALPKAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: REG2_PYRAB
Sequence: MRKLDKVDIQLVKILSQNSRLTYRELAELMNTTRQRIARRITKLKKLGVIKKFTIIPDLDKLGYMYAFVLVKLRVPSEVDAMISEISNVEYVKEIEKGVGRYNLIVRLLLPKDLKEAEGIINEFLQKIKNAESVEVVLISEIKKFEII
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator PYRAB00690.
Protein: RL132_BRANA
Sequence: MKHNNVIPNGHFKKHWQNYVKTWFNQPARKTRRRVARQKKAVKIFPRPTAGPLRPVVHGQTLKYNMKVRTGKGFTLEELKAAGIPKKLAPTIGISLDHRRKNRSLEGLQSNVQRLKTYKAKLVIFPRRARKVKAGDSTAEELANATQVQGDYMPIVREKQAMELVKLTSEMKSVNAYDKIRLERTNKRHAGARAKRAADAEKEEKK
What are the official names of this protein?
60S ribosomal protein L13-2, Cold-induced protein C24B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
Protein: TPIS_ACIBY
Sequence: MSGSTITPWVVGNWKMNPMRANANQLIEEFKQLLQQNQIADENCHVGVAPVSIALTTVQAQLQDAARTVHTVAQDVSRVAGTGAYTGEVSAELLKDSQINFVLVGHSERRDIFGDNVEILKAKLQNALNAGMTVIYCVGESLEQREQGQAEQVVLQQICDIAPVVTAEQWQNQVVIAYEPIWAIGTGKTASPQDAQAMHAKIREGLCQLTPAGSNIAILYGGSVKAENAVELAACPDINGALVGGASLKAASFYQIVQAFAQSK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBE_LOTJA
Sequence: MSGSTGERSFADIITSIRYWIIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDPLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ARLY_STRAW
Sequence: MSSNSGDVRLWGGRFADGPAEALAKLSASVHFDWRLAPYDIAGSRAHARVLHKANLLTDDELDRMLAGLDRLEADVADGTFVGTIADEDVHTALERGLLERLGPDLGGKLRAGRSRNDQVATLFRMYLRDHARVIGGLLADLQDALIGLAEAHPDVAMPGRTHLQHAQPVLFAHHVLAHVQALSRDAERLRQWDERTAVSPYGSGALAGSSLGLDPESVAKDLGFEHGSVANSIDGTASRDFVAEFAFITAMIGVNLSRIAEEVIIWNTKEFSFVTLHDAFSTGSSIMPQKKNPDIAELARGKSGRLIGNLTGLMATLKALPLAYNRDLQEDKEPVFDSCDQLEVLLPAFTGMMATLTVHRERMEELAPAGFSLATDIAEWLVKQGVPFRVAHEVAGECVKVAEGEGIELDGLTDEQFAKISSHLTPEVRGVLNVPGALASRDGRGGTAPSAVAVQLAEVRTDVAAQHAWATAKQKN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDST_CAEBR
Sequence: MIITPYLNPRLVKPLKWLAIIILLYFLYFSLFSINKKPGKPRKPPKAVENYTCPFEKADFSNFKDKKLEFHKNNGTDPKILVILDSLFSRHGKSIIQILNSQKFAFKAEAISKNLPVLTSAKRGKYSLIIVENYYKYLNMARWNRQLLDKYCKEYRVPLFSFIASKPNDQLKRIRIKGSSLWMWQNQRINRLTVSPSPIHKISKIGAYRNLTTQESDWILFEISENFESILTGTVKNGYERAVVLRDLGREDGVEKVIFGRNLTDFQIKITFLDALWWAMGDEKLFGLDRFVQVDIDDVFVGAQSTRIVEEDVRHLISAQNHFRNFIENFKFLLGFSGSYFRNGDDFEDRGDEILIENAEKFVWFPHMWRHNHAHEHNFTYLESIMVQNRLFAQNMHLPIDYPYAIAPQHDGVFPVHEQMYEAWKKIWNVTVTATEEYPHLKPATGRKGFIHSGIHVLPRQTCGLYTHTQFFDEYPEGFQKVIKSIQGGDLFFTILLNPISIFMTHQQNYAHDRLALYTFENLFRFLNCWTNIRLKWQSPVESAKMYFEKFPEERIPLWTNPCSDPRHQAILPPSMSCSKKSLPDLLIIGPQKTGSTALASFLALHPNVSQNMEIPGSFEEIQFFSGQNYLKGVEWYMSKFPNETTVIFEKSATYFDNPSAARQAAAMVPHAKLVIILQNPTQRAYSWFQSLFQHLIAHKDPIAMSSESLDVILNSTSSESAKFKIRQRCLSGGRYVHHLDKWLEHFSLQQIQFIDSDELRKEPAKVLSSLSKWLDLPEFPFETHIRFSPSKGFHCRLINGKTECLGESKGRKYSEMSQELRQKLDGIFALDNSALFKFLRKNRLKIPDWLEEAVRIRV
What is the function of this protein?
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate.  Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis (By similarity).
What are the official names of this protein?
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, Glucosaminyl N-deacetylase/N-sulfotransferase 1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family. NDST subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: HSLU_PECCP
Sequence: MSEMTPREIVSELDSYIIGQHKAKRAVSIALRNRWRRMQLDEALRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAIKMVRLQSIEKNRFRAEEMAEDRILDVLIPPAKNNWGQAESTPEPSAARQAFRKKLREGQLDDKEIEIDLAAAPVGVEIMAPPGMEEMTNQLQSMFQNLAGQKQKARKIKIKDAFKLLIEEEAAKLVNPEELKQQAIEAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVASPSDLIPELQGRLPIRVELQALTTEDFERILTEPSASLTEQYKALMATEGVDISFTADGIRRIAEAAWQVNESTENIGARRLHTVMERLIEDVSYDASEMNGQSVTIDADYVRNHLDELVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_PECCP
Sequence: MTAQPTILKIRRPDDWHIHLRDDRMLETVLPYTSRFFGRAIVMPNLTPPITTVASAIAYRQRILAAVPQGDDFHPLMTCYLTDALDANEIVSGFEQGVFTAAKLYPANATTNSSHGVTSVANISGILEKMQKIGMPLLIHGEVTDAAVDIFDREARFIETVLEPLRQQFPELKVVLEHITTKEAAQYVVEGNDYLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNTHQQALREAVASGCERLFLGTDSAPHAKHRKESSCGCAGVFNAQAALSTYATVFEEMNALDKLEAFCSLNGPRFYGLPVNDSWIELYRETVTFPEEISLGDESLIPFLAGQSLNWSVR
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: TSPY4_HUMAN
Sequence: MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS
What is the function of this protein?
May be involved in sperm differentiation and proliferation.
What are the official names of this protein?
Testis-specific Y-encoded protein 4.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OSBL1_MOUSE
Sequence: MNTEAEQQLLHHARNGNAEEVRKLLAAMARMEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVEDLLKAGAKVNMLNDMGDTPLHRAAFTGRKELVLLLLEYDADSTVVNGSGQTAKEATHDKEIRNMLEAVERTQQRKLEELLLGAAREGRTAEVSALLSRPNPPDVNCSDQLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDLAQGAEMKHILVGNKVVHKALKRYEGPLWKSSRFFGWKLFWVVLEHGVLSWYRKQPDAVHNSYRQGCKHLTQAVCTVKPTDSCLFSIRCFDDTVHCFRVPKNSVQQSREKWLEAIEEHSAYSTHYCSQDQVTDDEEEDVVSAMDLKESLARAQTCQQRLDREIYNFLKMIKECDVAKDMLPSFLQKADIVSEASRETCVALNDCLNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEHHELERSLVEGSPPVSILSEEEFYDALSGSESEGSLTCLEAVTAHSFEENEVPGSSGKHRMSEGKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLDHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQTSSSEESDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDLASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY
What is the function of this protein?
Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate.  Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A.  Binds 25-hydroxycholesterol and cholesterol.
What are the official names of this protein?
Oxysterol-binding protein-related protein 1, ORP-1, OSBP-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Late endosome. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes.
Protein: SECB_NEOSM
Sequence: MPDKDEITHDAQSENEESLPLARPEGQFMKSIALDTPNSPEVFSIMKNPPEVDVQCNIDSRAIDERNGVYEVVLDLKTEARIKDKDSPDETRVAFVCKLKYCGVFTIKNLTQEQLRQTLLVEAPTLLFPFARRIIATATTDAGFPPLMLAPINFAQKYAESQRD
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQBG_BACSU
Sequence: MLLITPDELKSYSVFESVKTRPDELLKQDILEATADIILKVGHDFSDAEYIPLPETVRLALLKLSQFYALINGDESIIKGYTTEKIGDYSYTLGDGSSLQKPDVYALIKDYVKPADPDLEGIEAKVRMRSI
What are the official names of this protein?
Uncharacterized protein YqbG.
Protein: NADE_SULAC
Sequence: MPEYVREKLTLNFPLVTEYLVKRIKDYINNSGKSGGIIGLSGGIDSSVASVLLSKATENFHVLLMPSSSTPKEDLDHAFMILRLINATESKYTIINIDPIVDQFRLAVKTNDKIISGNIKARSRMILLYAFAQKFNYLVVGTGDKSELMLGYFTKYGDGGVDILPLGDLYKTQVRMLGRYLGVPEDIVKKPPSPALWEGQTAEGEIGLDYETIDSILYLRFEEMRSENEISALVNVPIDLVRRIVRMVKISQHKRLPPEIFRLSGRSINSDWRYPRQWA
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: GDS_OCIBA
Sequence: MTNMFASAAPISTNNTTVEDMRRSVTYHPSVWKDHFLDYASGITEVEMEQLQKQKERIKTLLAQTLDDFVLKIELIDAIQRLGVGYHFEKEINHSLRQIYDTFQISSKDNDIRVVALRFRLLRQHGYPVPSDVFKKFIDNQGRLDESVMNNVEGMLSLYEASNYGMEGEDILDKALEISTSHLEPLASRSRRINEALEMPISKTLVRLGARKFISIYEEDESRDEDLLKFAKLDFNILQKIHQEELTHIARWWKELDLGNKLPFARDRVVECYFWILGVYFEPQYNIARRFMTKVIAMTSIIDDIYDVHGTLEELQRFTDAIRSWDIRAIDELPPYMRLCYEALLGMYAEMENEMVKQNQSYRIEYARQEMIKLVTTYMEEAKWCYSKYIPNMDEYMKLALVSGAYMMLATTSLVGILGDPITKQDFDWITNEPPILRAASVICRLMDDVVGHGIEQKISSVDCYMKENGCSKMEAVGEFSKRVKKAWKNLNEEWVEPRAASMVILVRVVNLARVINLLYVGEDSYGNSSVKTKELIKGVLVHPIK
What is the function of this protein?
Sesquiterpene synthase that catalyzes the formation of germacrene D from trans,trans-farnesyl diphosphate (FPP).
What are the official names of this protein?
Germacrene-D synthase, (-)-germacrene D synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.