PharMolix/UniProtQA huggingface dataset:
Protein: RISB_SYNY3
Sequence: MTVYEGSFTPPARPFRFALVIARFNDLVTEKLLSGCQDCLKRHGIDVDPAGTQVDYIWVPGSFEVPLVTRKLAVSGQYDAIICLGAVIRGQTPHFDFVAGEAAKGIAAIASQTGVPVIFGILTTDTMQQALERAGIKSNHGWGYAMNALEMASLMRAMAPLTEG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ANF_ACITR
Sequence: MMLKTVIYTGVLFLICNKVLVRADPLYSPYSSKDLANLKTLLERFEDTLGQDEGNDNQQDYDIANPEAEGPQAGSPWDRERERQWPASDYKKPQEGYQSQSSRLRDLLMAPRNNRGSSGCFGSRIDRIGSMSSMGCGGSRKG
What is the function of this protein?
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation.  Has a cGMP-stimulating activity (By similarity).
What are the official names of this protein?
Natriuretic peptides A, Prepronatriodilatin.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG_DICNV
Sequence: MILKGKKLLFMAGGTGGHVYPALAVARAAAEQGSIIHWLGNQSGFEGKKVPEAGFIFHDIAVYGLRGNGVIGWLKAPFMIGRAVFQAKKIMQHIQPDVVIGMGGFASGPGGIAAKILNIPLLIHEQNAVMGLTNALLSRVANTILLASQQAAAKIALKYPYRVTGNPVREDITLLPAPEERFHYRSGRIRLLVLGGSQGAKAINLLLPQALSLLPEEQRPQVLHQTGARWLEKTQTEYAALNVHAEIVPFIDDMAKAYANADWVIARSGALTVSEIATAGLAALFIPFPYAVDDHQTMNAQCLAEVGAAAILEEKTLTADILATAIQSRQDRSALLTQAERARLCSDEKALGEILRAIKELCR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL3_CROS8
Sequence: MIGLVGKKVGMTRIFTEEGVSIPVTVIEVEANRVTQVKDLANDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLADGEEYTVGQSISVELFAEVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQLGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: L_CDVO
Sequence: MDSVSVNQILYPEVHLDSPIVTNKLVSILEYARIRHNYQLLDTTLVRNIKERISEGFSNQMIINCIEIGSIINQTLLSYPKHNHVIYPNCNKLLFHAQDRVISLRLRNIFKRGNSIYSKITDGVKKCLNDINLNIGLGGALDKTIGTKIDEAGIIMQSSQWFEPFLLWFTIKTEMRSVIKSSTHNCRKRRQNPVFVKGESLNVLVSRDLVCIIDLTSHIVYYLTFEMVLMYCDVIEGRLMTDTAMAIDQRYSTLHVRIRYLWDLIDGFFPDLGNSTYQLVALLEPLSLAYLQLKDITFSLRGAFLSHCFAEIQEILQDNGFYTEETFQTLTQALDFVFITEDIHITGEIFSFFRSFGHPRLEAITAAENVRKHMNQPKVVSYETMMKGHAIFCGIIINGYRDRHGGTWPPMDLPVHASPIIRNAHASGEGITYSQCIENWKSFAGIRFKCFMPLSLDSDLTMYLKDKALAALRKEWDSVYPKEFLRYNPPRSTESRRLVNVFLEDSQFDPYNMIMYVISGQYLEDPDFNLSYSLKEKEIKEVGRLFAKMTYKMRACQVIAENLISNGIGKYFKDNGMAKDEHDLTKSLHTLAVSGVPKDKKDSHRGLTNQRKSLKPAPYRGTRHSVSSPSSRYIDPNPNFCTSRREDNDIEIYETVSAFITTDLKKYCLNWRYETISIFAQRLNEIYGLPSFFQWLHRRLEQSILYVSDPHCPPDLDRHVDLNTAPNSQIFIKYPMGGVEGYCQKLWTISTIPYLYLAAHESGVRIASLVQGDNQTIAVTKRVPSTWSYALKKSEASRVTTEYFIALRQRLHDVGHHLKANETIISSHFFVYSKGIYYDGMLISQSLKSIARCVFWSETIVDETRAACSNISTTLAKAIEKGFDRYLAYTLNILKIIQQVLISLGFTINSAMTRDVIEPLLQDHCLLTKMAILPAPIGGFNYLNMSRLFVRNIGDPVTSSIADLKRMIRSGLLGVEILHQVMTQYPGDSSYLDWASDPYSANLPCVQSITRLLKNITARHVLINSPNPMLRGLFHDESQDEDEALAAFLMDRKIIIPRAAHEILDNTITGAREAIAGMLDTTKGLIRASMKRGGLTPRIITRLSTYDYEQFRAGIRLFSGKGHDQLIDQDSCSVQLARALRNHMWAKLAKGRPIYGLEVPDILESMKGYMIRRHESCLLCASGSHNYGWFFIPANCQLDSITEGTSALRVPYIGSTTEERTDMKLAFVKSPSRSLKSAVRIATVYSWAYGDDDESWQEAWTLAKQRADISLEELRMITPISTSTNLAHRLRDKSTQVKYSGTSLIRVARYATISNDNLSFIIDDKKVDTNFIYQQGMLLGLGILEHLFRLSSTTGDSNTVLHLHVETDCCVIPMSDHPRVPGLRKVVIPRNICTNPLIYDSNPIIEKDAVRLYNQSHRKHIVEFVTWTTGQLYHVLAKSTAMSMVEMITKFEKDHLNEVTALIGDDDINSFITEFLLVEPRLFTVYLGQCAAINWGFEIHYHRPSGKYQMGELLFSFLSRMSKGVFKILANALSHPKVYRRFWDSGMIEPVHGPSLDSQNLHITVCNLIYNCYMIYLDLLLNDELDDFSFILCESDEDVIPERFDNIQARHLCILSDLYCNPRDCPQIRGLTPTQKCAVLSGYLKSKALESHVGLTWNDKPILIDQYSCSLTYLRRGSIKQIRLRVDPGFITDAVGCLERRPLRNNSTSKASELTSGFDPPKDDLAKLLSQLSTRTHNLPITGLGVRNYEVHSFRRIGINSTACYKAVEIASVIKNEFTSEEHGLFLGEGSGAMLTVYKELLRLSRCYYNSGVSVESRTGQREISPYPSEVSLVEHQLGLDKLVTVLFNGRPEVTWVGSVDCYKYILSQISASSLGLIHSDIESLPDKDIIEKLEELSAILSMTLILGKVGSVLVIKIMPVSGDWVQGFILYALPHFLRSFIVYPRYSNFVSTEAYLVFTGLRAGRLINPEGIKQQILRVGIRTSPGLVGHILSSKQTACVQSLHGPPFHAKSFNPHLQGLTSIEKVLINCGLTINGLKVCKNLLHHDISSGEEGLKGSITILYRELARFKDNHQSSHGMFHAYPVLIASQERELVSIIAKKYCGYILLYSGDLYEITRIVRNLKANHIIFDLHRNLFMDNLSRSDRSLILTTIPKKNWLFQLETKEIKEWFKLLGYSALIRNH
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: SYT_ECOL6
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y169_LISMO
Sequence: MNIVIALIPAVMWGIMPLVVSKIGGKPRQQIIGTTFGALAFAIGVFIFTNPEYTATIIIASFVSGAFWSLGQMNQFRAFTQVGVSKTMPLSTGMQLVGTSLFGVFAFHEWGTTSKLVLGFSALALIIIGIFLTSYQQHKDENSGQNMKKGIITLLISSVGYVGYVVITRWFDISGWDAILPQAIGMVVAGLLFSIKSEEKRFTKQTWLNMIPGVMWATGNLALLFSNKLVGIATGFSLSQMGVVISTIGGILFLGEKKTKKELILVIIGVVLVIIGGTMIGIAKS
What are the official names of this protein?
Putative sugar uptake protein lmo0169.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ALG11_CAEEL
Sequence: MSDTVISLISHSITTVFYLVPLIIALIIPFSLYSGFRRKSKTVAFFHPYCNAGGGGERVLWAAIRTMQKKFPDHKYFVYSGDTDATKEQILLKARQRFGIELDPSNIQFIYLHWRTLVEARHYKHCTMLFQALAGLILALEAWFRMVPAVFIDSMGYPLSLPAFRLSGSKVVAYVHYPTISCDMLDVVESRQETFNNSSTIAQSNVLSWGKLTYYRLFACLYWLAGKAAHVGMVNGSWTQRHITSIWSRRDVSIVYPPCDVEAFLNIESVAESLLEDTKTVRLLSVGQIRPEKNHKLQLEVLHDVKEPLEKMGYNVELCIAGGCRNEEDQERVKMLKNEAEKLDISEQLIWQLNVPYEDLVVELSKALISIHTMHNEHFGISVVEAMAASTIILSNDSGGPRMDIVKDYEGHCVGYLSITKEEYVETILKIVEEGLKKRNDTRKYARKSLTRFGEAAFETHWNKEIEKVL
What is the function of this protein?
Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.  Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain.
What are the official names of this protein?
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYI_STRP4
Sequence: MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELNQGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIEQVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYEAAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGKGVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPVGEARKFVVAAELLTSLSEKFGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGEDDYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGDWVISRQRTWGVPLPIFYAEDGTAIMVAETIEHVAQLFEKHGSSIWWERDAKDLLPEGFTHPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSSLITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTSVDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMTIRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQMQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILDTWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIVSELTIAEEPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASIVEENFADAVAEGFEEK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_PSEPK
Sequence: MAIVKCKPTSPGRRFVVKVVNKELHKGAPHAPLIEKKSKSGGRNNNGRITTRHVGGGHKQHYRLVDFRRNDKDGIPATVERIEYDPNRTAHIALLCYADGERRYIIAPKGVSAGDQLIAGALAPIKAGNSLQLRNIPVGSTIHGIELKPGKGAQIARSAGASAQLIAREGVYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGFPTKGAKTRGNKRTDNMIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: VP16_HHV23
Sequence: MDLLVDDLFADADGVSPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSGFPTNADMYRECKFLSTLPSDVIDWGDAHVPERSPIDIRAHGDVAFPTLPATRDELPSYYEAMAQFFRGELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRNRDLREMLRTTIADRYYRETARLARVLFLHLYLFLSREILWAAYAEQMMRPDLFDGLCCDLESWRQLACLFQPLMFINGSLTVRGVPVEARRLRELNHIREHLNLPLVRSAAAEEPGAPLTTPPVLQGNQARSSGYFMLLIRAKLDSYSSVATSEGESVMREHAYSRGRTRNNYGSTIEGLLDLPDDDDAPAEAGLVAPRMSFLSAGQRPRRLSTTAPITDVSLGDELRLDGEEVDMTPADALDDFDLEMLGDVESPSPGMTHDPVSYGALDVDDFEFEQMFTDAMGIDDFGG
What is the function of this protein?
May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.
What are the official names of this protein?
Tegument protein VP16, Alpha trans-inducing protein, Alpha-TIF, ICP25, Vmw65.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae tegument protein VP16 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus.
Protein: EFP_FUSNN
Sequence: MKIAQELRAGSTIKIGNDPFVVLKAEYNKSGRNAAVVKFKMKNLISGNISDAVYKADDKMDDIKLDKVKAIYSYQNGDSYIFSNPETWEEIELKGEDLGDALNYLEEEMPLDVVYYESTAVAVELPTFVEREVTYTEPGLRGDTSGKVMKPARINTGFEVQVPLFVEQGEWIKIDTRTNEYVERVKK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_SHEON
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMASSLVRHEIIKTTVAKAKELRRVVEPLITLAKSDSVANRRLAFARTRDAEVVGKLFTELGPRYQERPGGYTRILKCGLRAGDKAPMAYIELVGRPEAAQAVDVEAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: O52L2_HUMAN
Sequence: MNLDSFFSFLLKSLIMALSNSSWRLPQPSFFLVGIPGLEESQHWIALPLGILYLLALVGNVTILFIIWMDPSLHQSMYLFLSMLAAIDLVVASSTAPKALAVLLVRAQEIGYTVCLIQMFFTHAFSSMESGVLVAMALDRYVAICHPLHHSTILHPGVIGHIGMVVLVRGLLLLIPFLILLRKLIFCQATIIGHAYCEHMAVVKLACSETTVNRAYGLTVALLVVGLDVLAIGVSYAHILQAVLKVPGNEARLKAFSTCGSHVCVILVFYIPGMFSFLTHRFGHHVPHHVHVLLAILYRLVPPALNPLVYRVKTQKIHQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Putative olfactory receptor 52L2, Olfactory receptor OR11-74.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUD1_PYRFU
Sequence: MKARGRAWKYGDNIDTDVIIPARYLNTSDPKELAQHVLEDLDPEFRYKMKPGDIIVAGENFGCGSSREHAPLAIKAAGVSAVIAKSFARIFYRNAINIGLPILEAPEAVERIETGDEIEIDFSTGEIRNLTKGEVYHANPFPEFIMEIIKAGGLVEWAKRRLAK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit 1, Alpha-IPM isomerase 1, IPMI 1, Isopropylmalate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: SYM_YERPE
Sequence: MAQVAKKILVTCALPYANGSIHLGHMLEHIQADIWVRFQRMRGNQVHFICADDAHGTPIMLKAQQMGIEPEQMIAEMSQEHQQDFAGFAISYDNYHSTHSDENRELSSLIYGRLKANGYIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKAPEQYGDNCEVCGATYSPTELIDPKSAVSGATPVMRESEHFFFDLPAFSDMLQAWTRSGALQEQVANKMQEWFDSGLQQWDITRDAPYFGFEVPDAPGKYFYVWLDAPIGYMGAFKNLCDKRGDLDFDEFWGKDAKTDLYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKAGTYLKYLDADCLRYYYAAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFAGQLADQLADPVLYKTFTDAATSIADAYNNRESGKAIREIMALADVANRYVDEQAPWVVAKQEGRDADLHAICSMGINLFRVLMTYLKPVLPSLTERTEAFLNTELTWDSIEQPLLGHSITAFKALFNRIDLDKVNEMVASSKEDMAPATRVTGPLADDPIQETISFDDFAKVDMRIALIQQAEFVEGSDKLLKLTLELGGETRQVFSGIRSAYPDPKALEGRMTVMVANLAPRKMRFGVSEGMVMAAGPGGSDIFLLSPDSGAQPGMQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_ECOL6
Sequence: MKRMIALDGAQGEGGGQILRSALSLPMITGQPFTITGIRAGRAKPGLLRQHLTAVKAAAEICRATVEGAELGSQRLVFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLARIGVHQQTTLLRHGFYPAGGGVVATEVSPVASFNSLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLQTNIAVVERFLPVRFSLIETDGVTRVSIE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_KORVE
Sequence: MARIAGVDLPRNKYINIALTYIFGIGNSRAKAILAEANVEANRKVSDLNEEEVNRIRTAIENGSSVEGDLRKDVSMHIKRLIEIGSYRGYRHRRSLPVRGQRTHTNARTRKGPRKGTVANKKKATAK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ARGP_SHIDS
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPESRMMRKVTDALLDYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: CYB_PETXN
Sequence: MTNIRKTHPLIKIVNHSFIDLPTPSNISAWWNFGSLLGLCLVTQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLYLHVGRGLYYGSYTYFETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGLSVDKATLTRFFAFHFILPFIVAALAMIHLLFLHETGSNNPSGLISDSDKIPFHPYFTIKDILGVLLLILTLMILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHTSKQRGMMFRPLSQCLFWILAADLLTLTWIGGQPVEHPFIIIGQMASILYFTIILIVLPLISLLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RK16_CUSGR
Sequence: MLSPKKTRFRRQHRGRMKGLASRGNHISFGKYGLQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTIRPAETRMGSGKGSPEFWVSVVKPGRILYEMDGVTKNVAKRAFGIAASKMPIRTQFIFSEIK
What are the official names of this protein?
50S ribosomal protein L16, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid.
Protein: MURC_STRP4
Sequence: MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRDFVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHFMPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDAPIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIGLLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKYPSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLANKINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_SHESA
Sequence: MPEELSKKQITRLNKLQKRLRREVGSAIADYNMIEDGDRVMCCLSGGKDSYAMLDILLNLQQRAPVQFEIIAVNLDQKQPGFPEHVLPAYLDSLNIPYHILEKDTYSIVKEKIPEGKTTCSLCSRLRRGTLYGFAQRIGATKIALGHHRDDIIETMFLNMFYGGKMKAMPPKLLSDDGANVVIRPLAYCREKDLEEYAELKKFPIIPCNLCGSQENLKRQAVKDMLNQWDRLYPGRIETIFTAMQNTAPSQGVDREQFDFVSLKRDPNAPMKGDVAEADLPAFDFLDIANSGHIDLDAAKRINIVNVYEA
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_RALSO
Sequence: MAIRQATTPQHDAGTVLERKEQALKPPAMYKVLLLNDDYTPMEFVVMILQQYFSKDRETATQIMLTVHREGRGVCGIYTRDIAATKVELVSTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: ERA_NEIMF
Sequence: MDIETFLAGERAAGGYRCGFVAIVGRPNVGKSTLMNHLIGQKISITSKKAQTTRNRVTGIYTDDTAQFVFVDTPGFQTDHRNALNDRLNQNVTEALGGVDVVVFVVEAMRFTDADRVVLKQLPKHTPVILVVNKIDKDKAKDRYALEAFVAQVRAEFEFAAAEAVSAKHGLRIANLLELLKPYLPESVPMYPEDMVTDKSARFLAMEIVREKLFRYLGEELPYAMNVEVEQFEEEDGLNRIYIAVLVDKESQKAILIGKGGERLKKISTEARLDMEKLFDTKVFLKVWVKVKSGWADDIRFLRELGL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RF1_RICPU
Sequence: MRFSDNLAKILDKYENLGNTLSSGIMGDEFVKASKEYAELEDVVAKIKEYNKAKSELEEANNFKLEVGLDNATLEMIEDEIYTLENSLPKLERAVKIALLPKDDADSKSAIIEVRAGSGGEEAALFAAVLFNMYQRYAELKGWRFEILAISDTGIGGYKEASASIKGKDVFSKLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDIKIEDKDLRIDTYRASGAGGQHVNTTDSAVRITHIPTGITVALQDEKSQHKNKAKALKILRARIYEEERRKKEQERADSRRGQVGSGDRSERIRTYNFPQGRVSDHRINLTLYKIDEVVKNGQLDEFVEALIADDEAKKLLEI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.