PharMolix/UniProtQA huggingface dataset:
Protein: LGT_MYCGA
Sequence: MYTTGNHTINDSFGTAFMIGSFDVRYYGILYATGILVAIIAGILTLKYKYKVDDNPYFYYVFIGIISIIFGARTWSFIIGDSIVGVTPFFAIHQGGLAIQGGVIFTITTGLIFFFFILRKPKYYVKKNYLVYENHNLVTKTFYKQASMWIYADAIIPTILIGQAIGRWGNFFNHEVYGQGLTAEQALNQWGFLKVLMPGVFEHMFINENGVTLFRVPIFLIESFFNVIAFIIIVFLLDFVKELKTGGRTMLYFFTTGIIRLIIETQRDSQFKFVTSIVTSVLFLLGGSIGFIFTQWIFPRFRNKKNYFFLFNKVKIYFIGLFKNYLNKYKNLTKEEIRKKLEPSSTIYSKNFSEMFFYADDYDLMIKKD
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TPIS_RUEST
Sequence: MARKLAAGNWKMNGTGEHLAELENLAQGDLPEGVDVLICPPATLISRAADRAGDIAIGGQDCHAKTSGAHTGDLSADMLRDAGATYVIIGHSERRADHGEGDADVRAKTEAAQAAGLVAVVCIGETLEEREAGTTLEVVGAQLAGSLPDGVTAENTVVAYEPVWAIGTGKVPTLDQIAEVHDALRADLVARFGAAGKDLPLLYGGSVKPGNAAEIFGVSNVDGALVGGASLKAADFGPIIAALAAS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_ALISL
Sequence: MAEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFLDSDTVIEERTGADIAWVFDVEGEEGFRIREEGVINDLTQEQGIVLATGGGSVISKESRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQTDEPREVLEALAKERNALYEEVSDYVVRTDDQSAKVVANQIIQMLEER
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNE_CAEEL
Sequence: MAGRKSSRTAERVPTTQKPERKSAILSPHDELRERLLETAIDMKENIPQRNTRNSSVGSQKSDCSETRKRRSTKEGPAAKRHSGEKHRNGSREDSLEYISEYSDDREVGSSSSQSSRTRGQPLPAMPEEEEVFDKSSSSDNLAESEESHEMVRLEERQDIEEEIEDDFDDEEEDVVNDKEEYEEIESEDEDDYPVQNEGFAVTKRLMNDEHMVTAPTFLSTAKCDGIGSPTKVWSLMVKRDEIPRATRFLLGNHPDMDDEKRRILIDWMMEVCESEKLHRETFHLAVDYVDRYLESSNVECSTDNFQLVGTAALFIAAKYEEIYPPKCIDFAHLTDSAFTCDNIRTMEVLIVKYIGWSLGPITSIQWLSTYLQLLGTGKKNKSDHYEEQNMYVPELLRSEYLEMCKILDFLLFEIDSFTFSYRTIAAAVLFVNYEPTCAVEKATGFMQAQLEKVIEYVEPVCRAFAKQRQLLDDVIPKHESIKSDDSHNIQVYVKRSSMEPIVKSERERIQHLKARRLHPQRLF
What is the function of this protein?
Essential for the control of the cell cycle at the G1/S (start) transition (PubMed:12606285).  In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages (PubMed:10952902, PubMed:17476329, PubMed:21558371, PubMed:21455289).  In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase (PubMed:17115027).  During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase (PubMed:10952902, PubMed:20005870).  During hypoderm development at early larval stages, controls syncytial fate of seam cell daughter cells (PubMed:17476329).  Involved in the progression of cell division in the intestinal lineage in larvae, and in particular in endoreplication, a specific growth pathway in the intestinal epithelium, required for feeding and gut development in growing larvae (PubMed:17466069).  By controlling the activity of translational repressor gld-1, regulates the pool of germline stem cells and the size of the mitotic zone by preventing entry into meiosis (PubMed:21455289).  In addition, repression of expression by gld-1 prevents mitosis re-entry in meiotic germline cells (PubMed:19758560).
What are the official names of this protein?
G1/S-specific cyclin-E.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin E subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Co-localizes with cdk-2 in the sperm centrioles before the first embryonic mitosis and then to the male and female nuclei upon entry into mitosis.
Protein: MCPAL_TRIVH
Sequence: MQSLLLLATLLGSALGGAIPSQSANYNGYKVMRVSGDDTSKISHIVSKLGLETWKFPKAANANVDIVVPPKKVAEFEKMSHAAGLKKQVMHENLGDSIKSEMSFRPYSCELLTLDGGANDTWFQSYHKYEDHLKFMQDFQSAHSQNSEIVTSGKSHEGRDITGVHVWGSGEKGSKPAVVFHGTVHAREWITTMTVEYILAQLFDDKEAGAALLEKFDFYIFPIANPDGFVFTTESDRMWRKNREQNEGGCYGTDLNRNWPYKWEGDGSTTDPCSETYRGPSPGFAPETKASTSFIKGLADGAGVKMFVDWHSYSQLFMTPYGYSCSARAPNDDVLQEMASSFADAVKAVHGTSFTTGPICNTIYQANGNSVDWIVDEIKGETAFAAELRDTGMYGFVLPPEQIIPSGEETWAGVKAMFSKLK
What is the function of this protein?
Extracellular metalloprotease that contributes to pathogenicity.
What are the official names of this protein?
Metallocarboxypeptidase A-like protein TRV_02598.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZIPA_SHEPC
Sequence: MEDLQLVLFILGAIAIVAVLVHGFWSIRRQQPKSLKDSPMGNFYKQQADKESPPKRVDADGFDADGIGAVRVRKVGESNSHETPPISPYLKQDVKAEPKPLFKHTTSTEIKQEPVPQPDFSLQSPLATEQQRGAKVSRQEPVLNGHVPPLGQSHAAMVAQKALEQEKHAQSTTVPTQTALFDEDAYLENTESEDEYVEETVDEGLDEPRDVLVLHVVAKEGQQLNGAELLPCFLTLNFKYGDMNIFHRHVDNAGNGKVLFSIANMLKPGVFDPDNMEQFSTQGVVFFMTLPCYGDALMNFSIMLNSARQLADDIDAVVLDGQRQPWGEFTKQDYLHRIRANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: Y3081_VIBC1
Sequence: MNQQWNQYIQIIKQVVKPALGCTEPIAAAYAAAVAKRELGCQTPDTIEVRVSDNLFKNSMGVYVPGTGKIGLKIAASVGALAGDPNAELEVLAKINQDDVTAAQQLIDEERVSVARIDTQELIFCSVTMSAGEDTVSVTISGGHTNIIQITRNGVVTFDAPQQQRVATGSVCEGVDISIKQIYDFALQAPFDDIKFILQAAELNSSLAQEGIDRGYGLEIGRTLKGNIEQGLLGNDLMSRIQMMTSAASDARMGGATLPAMSNFGSGNQGIAATMPVVIAAEAFQSSEEHLARALIMSHLGAIYIKSYYPPLSAFCGNTVTSAAASMALVYLAGGTFEQSCYAIQNVISDSSGMVCDGAKSSCAMKVCTSATTAVRSYLMAMGNHSVKNQGIIGDEVEQTIRNVGSMVRLGMPYTDKSIIDIMSA
What are the official names of this protein?
UPF0597 protein VIBHAR_03081.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: GP350_EBVA8
Sequence: MEAALLVCQYTIQSLIQLTRDDPGFFNVEILEFPFYPACNVCTADVNATINFDVGGKKHKLNLDFGLLTPHTKAVYQPRGAFGGSENATNLFLLELLGAGELALTMRSKKLPINITTGEEQQVSLESVDVYFQDVFGTMWCHHAEMQNPVYLIPETVPYIKWDNCNSTNITAVVRAQGLDVTLPLSLPTSAQDSNFSVKTEMLGNEIDIECIMEDGEISQVLPGDNKFNITCSGYESHVPSGGILTSTSPVATPIPGTGYAYSLRLTPRPVSRFLGNNSILYVFYSGNGPKASGGDYCIQSNIVFSDEIPASQDMPTNTTDITYVGDNATYSVPMVTSEDANSPNVTVTAFWAWPNNTETDFKCKWTLTSGTPSGCENISGAFASNRTFDITVSGLGTAPKTLIITRTATNATTTTHKVIFSKAPESTTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPPVTTAQATVPVPPTSQPRFSNLSMLVLQWASLAVLTLLLLLVMADCAFRRNLSTSHTYTTPPYDDAETYV
What is the function of this protein?
Initiates virion attachment to host B-lymphocyte cell, leading to virus entry.  Acts by binding to host CR2 at the surface of B-lymphocytes, facilitating the binding of viral glycoprotein gp42 to HLA class II molecules.  Attachment triggers virion-host membrane fusion and invasion of the host cell (By similarity).
What are the official names of this protein?
Envelope glycoprotein GP350, Membrane antigen, MA.
What is the protein family that this protein belongs to?
Belongs to the Epstein-Barr GP350 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host membrane; Single-pass membrane protein. Note=Most abundant component of the viral envelope.
Protein: RL18_HAEDU
Sequence: MDKKVARIRRASRARHLMREQGATRLVVHRTPRHIYAQVIAPNGSEVLAAASTVEKVIKEQVQYTGNKDAAAIVGKLVAERALAKGIQVVAFDRSGFKYHGRVQVLADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PNS1_CRYNB
Sequence: MSAQEFYQGGNQRGYQQQQFPPPPGGPPQDQNGGKQEYVPPQGQPPNYNMKPSQPYASTNPETGGQPVYQDTAPFSQANEKTGERMNPRKRVNDIIPLILFIAAVVGFAVVSGIAIHGFVQVNGLGGGMGDSSIGRTGSSITLDYHTVYLLLVVVALGLVIASLYLAALRAFTKIILEVTLALTVILNIGICIYYFIIQYWSGAIIFLIIALVSVFFYWGMRKRIPLAKLLLQTTIDVTKHHPSVYVVVFIGLIIQAAVSVWYTFTCIAIYVKWTPGSAACSDGGCSSSKVAGLVFYATFSYLWLSQVIGNVILCTLAGGVFGGWYYYGPRTPGGGVPKRASLLAFVRASTLSLGSIAFGSLLVTILELLRLILQLFRQYEAGQGDMIGSILICIAQCCIGCIQWMVEYFNKYAYIEIALYGKSYIPAAKDTWRLLKDRGIDALVNDSLVGTALMWGAYINGFLCAVLGYFYLRFTHPAYNSDGQYSAPVILFSFLIGLNESFTVGSAIDAGVSTIFVGLGEDPMVLAERSPGLFEMIRQVYPRVVQGVPH
What is the function of this protein?
Probably involved in transport through the plasma membrane.
What are the official names of this protein?
Protein PNS1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS27A_CAEEL
Sequence: MVFVKTLHRTLFLEVAANEDVLSIKQKIEAAEGIPAEEQRLCYAGRQLEDSDCGIDSEATIYVNLELLGGAKKRKKKVYTTPKKNKRKPKKVKLAVLKYYKIDENGKITRLRKECQQPSCGGGVFMAQHANRHYCGRCHDTLVVDTATAAATSGEKGGKKGKK
What are the official names of this protein?
Ubiquitin-like protein 1-40S ribosomal protein S27a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
Protein: KISHA_XENTR
Sequence: MSAIFNFQSLLIVILLLICTCAYLRALVPNLLDKNKTGILGIFWKCARIGERKSPYVAVCCVVMAFSILFMQ
What is the function of this protein?
Involved in the early part of the secretory pathway.
What are the official names of this protein?
Protein kish-A, Transmembrane protein 167, Transmembrane protein 167A.
What is the protein family that this protein belongs to?
Belongs to the KISH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein.
Protein: 6PGL_ECODH
Sequence: MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: SODC_CAVPO
Sequence: MATKAVCVLKGDGPVQGIIHFEQKANGPVVVKGRITGLVEGKHGFHVHEFGDNTQGCTSAGPHFNPLSKKHGGPQDEERHVGDLGNVTAGADGVANVSIEDSLISLSGANSIIGRTMVVHEKPDDLGKGGNEESTKTGNAGSRLACGVIGIAQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RHAD_CITK8
Sequence: MQNITHSWFVQGMIKATSDAWLKGWDERNGGNLTLRLDEADIAPFTDDFHQEPRYIALSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKVDSDGAGYHILWGLNHEAVPTSELPAHFLSHCERINATDGKDRVIMHCHATNLIALTYVLENNTPLFTRKLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAEVLVKIYSMGGMKQTITREELVALGKRFGVTPLASALALY
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPA3_PSEAB
Sequence: MRKILPLRAWLAAGLILGSPFSHAASNLVFCSEGSPAGFDPAQYTTGTDYDATSVTLFNRLVQFERGGTRAIPALAESWDIGDDGKTYTFHLRKGVKFHSTDYFKPTREFNADDVLFTFERMLDKNHPFRKAYPTEFPYFTDMGLDKNIARVEKLDEHRVKFTLNEVDAAFIQNLAMDVASIQSAEYAGQLLEAGKPQQINQKPIGTGPFILSRYQKDAQIRFKGNKDYWKPEDVKIDNLIFSINTDAAVRAQKLKAGECQITLNPRPADLKALQEAANLKVPSQPGFNLGYIAYNVTHKPFDQLEVRQALDMAVNKQAIIDAVYQGAGQLAVNGMPPTQWSYDETIKDAPFDPAKARELLKKAGVAEGTEITLWAMPVQRPYNPNAKLMAEMIQADWAKIGIKARIVSYEWGEYIKRAHAGEHDAMLFGWTGDNGDPDNWLATLYGCDSINGNNVSKWCDAAYDKLVKAAKRVSDQDKRSELYKQAQHILKEQVPITPIAHSTVYQPMNKSVHDFKISPFSRNAFYGVTNQP
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in the uptake of various di/tripeptides (PubMed:25338022).  Prefers dipeptides with acidic residues at the C-terminal end.  Involved in the uptake of phaseolotoxin, a toxic tripeptide inhibiting the enzyme ornithine carbamoyltransferase (PubMed:25338022).
What are the official names of this protein?
Di/tripeptide-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
Protein: RUVB_DESOH
Sequence: MKEKILTFSSDPSSPVTRHETEEDTGDDLFSLRPCDFEDYVGQDRTVETLRIAIAAAKQRSEPLEHVLFHGPPGLGKTTLAHIIAAEMGTSLTITSGPALEKGGDLIGMLTHLKRGDILFVDEIHRLPRTTEEFLYPAMEDFAVDFVFDKGIHARCHRYRLNQFVLVGATTRVGLLSAPLRDRFGIFRKFDFYSRQDLARIVSRSAALMGLTIDETCTMELARRSRGTPRIVNRLLKRVRDYVQVRHGGVITVSAIDDALALEGVDEKGLTGLDRSYLETIIQYYGGGPVGIEAIGATLQEETDTLVDVVEPFLLAEGLLQRTSSGRKATEAAYRHLGVQWRG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y1262_PROM9
Sequence: MNFLTNQLLIQEEIEALIKNLNKENTLWEDGKKTAGSHASMVKNNLQLNRESEISKKLSHLIKKKILSSPLIKSFALPKIIHGIMFTKSLKDMQYGRHIDNPFMSSGRADLSFTISLTDKNTYDGGELIIEEMNSEKEFKLNAGEIIIYPSTYLHSVKEIKNGERLVCVGWIESYVKSIEQREYLFDLDAGAKGLLAKNGRSDELDLIFKSYSNLLRLLGN
What are the official names of this protein?
PKHD-type hydroxylase PMT9312_1262.
Protein: DNLJ_YERPN
Sequence: MESIIQQINQLRTSLRHHEHQYHVLDAPEIPDAEYDRMMQQLRDLEAQHPELVTNDSPTQRVGAAPLDAFEQVKHEVPMLSLDNVFDEESYLAFDKRVHDRLKTAEPLTFCCELKLDGLAVSLLYENGELVRAATRGDGTTGENITANVRTIRAIPLRLHGDNVPRRVEVRGEVFMPQAGFEQLNEEARRKGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGLLDGGELPRSHIQCLMQFKAWGLPVSERVKLCTGSDQVIAFYRQIEQDRAGLGFDIDGVVIKVDDLALQEQLGFVARAPRWATAFKFPAQEQITQVREVEFQVGRTGAITPVARLEPVQVAGVIVSNATLHNADEIERLGLRIGDTVIVRRAGDVIPQVVGVVMEQRPDDTKEITFPSQCPVCGSDIERVEGEAVARCTGGLFCAAQRKEALKHFVSRRALDVDGMGDKIIEQLVEKQYVENPADLFQLTAGKLTGLDRMGPKSAQNLIAALEKAKQTTFARFLYALGIREVGEATAANLAAHFRTLDNLRAADIETLKSVPDVGEVVAKHVMNFLSEEHNQKVIEELEKVVSWPEPQQIVVEESDSPFAGKTVVLTGSLTILSRDEAKDRLTALGAKVSGSVSKKTHLVIAGEAAGSKLAKAQELGIKVIDEAEMIRLLGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ATPE_GEOUR
Sequence: MAEKLKVELVTPYKRVLSEEVDEITATGALGEFGVLPGHAPFLTSLKIGELAYKKDGVQQHMALNWGYFEVEGDKVTVLVETAERADEIDLERAKAALGRAEEALKKLSPEDKSFRIYEAALERAAIRMQVAAKAARK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPF_NEIMF
Sequence: MRKIRTKICGITTPEDASAAVAAGADAVGLVFFQGSSRAVDIARAKKITAALPPFVSVVALFVNESAQNIRRILAEVPIHIIQFHGDEDDTFCRQFDRPYIKAIRVQTASDIRNAADRFPDAQALLFDAYHPSEYGGTGHRFDWTLLAEYSGKPWVLAGGLTPENVGEAVRITGAEAVDVSGGVEASKGKKDPAKVAAFIATANRLSR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: LEU3_LACLA
Sequence: MSKKIVTLAGDGIGPEIMSAGLSVLKAVSKKIDFEYELEAKDFGGIAIDKHGHPLPEETLQAVKNADAILLAAIGHPKYNNAKVRPEQGLLALRKELGLYANVRPLKIYPALKKLSPIRNVENVDFLVIRELTGGIYFGQHELADDKARDVNDYSADEIRRILHFAFKSAQSRPRKLLTSVDKQNVLATSKLWRKMADEIADEYPDVRLEHQLVDSCAMLLITNPQQFDVIVTENLFGDILSDEASSLAGSLGVMPSSSHGFNGLALYEPIHGSAPDIAGKGIANPVSMILSIAMMLRESFGQEDGAAMIEKAVTQTFTDGILTKDLGGTATTKEMTEAILKNCQ
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_STRTD
Sequence: MSNYAIILAAGKGTRMKSDLPKVLHKVSGITMLEHVFRAVSVIEPAKNVTVIGHKAELVREVLDGQSAFTMQTEQLGTGHAVMMAEEELAGLEGQTLVIAGDTPLITGESLKNLIDFHVNHKNVATILTATADNPFGYGRIIRNENGEVTKIVEQKDANKFEQQVKEINTGTYVFDNKRLFEALKNINTNNAQGEYYLTDVISIFRENGEKVGAYTLRDFEESLGVNDRVALATAEDVMRRRINKTHMINGVTFQNPNATYIDVDVEIAPDVVIEANVTLKGKTKVGAESVLTNGTYIVDSTIGANTVITNSMIEHSVVEKGATVGPFAHIRPDSMLKEGVHIGNFVEVKGSTIGENTKAGHLTYIGNAEVGSDVNFGAGTITVNYDGQHKFKTQIANNAFIGSNSTLIAPLEIGDNALTAAGSTITDNVPADSVAIGRSRQVNKEGYAIKKPHHPSQQK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_ECOLC
Sequence: MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OXDD_BACSU
Sequence: MLLEQQPINHEDRNVPQPIRSDGAGAIDTGPRNIIRDIQNPNIFVPPVTDEGMIPNLRFSFSDAPMKLDHGGWSREITVRQLPISTAIAGVNMSLTAGGVRELHWHKQAEWAYMLLGRARITAVDQDGRNFIADVGPGDLWYFPAGIPHSIQGLEHCEFLLVFDDGNFSEFSTLTISDWLAHTPKDVLSANFGVPENAFNSLPSEQVYIYQGNVPGSVASEDIQSPYGKVPMTFKHELLNQPPIQMPGGSVRIVDSSNFPISKTIAAALVQIEPGAMRELHWHPNSDEWQYYLTGQGRMTVFIGNGTARTFDYRAGDVGYVPSNAGHYIQNTGTETLWFLEMFKSNRYADVSLNQWMALTPKELVQSNLNAGSVMLDSLRKKKVPVVKYPGT
What is the function of this protein?
Converts oxalate to formate and CO(2).
What are the official names of this protein?
Oxalate decarboxylase OxdD.
What is the protein family that this protein belongs to?
To B.subtilis OxdC.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IES4_YEAST
Sequence: MSQESSVLSESQEQLANNPKIEDTSPPSANSRDNSKPVLPWDYKNKAIEIKSFSGYKVNFTGWIRRDVREERQRGSEFTASDVKGSDDKATRKKEPADEDPEVKQLEKEGEDGLDS
What are the official names of this protein?
Ino eighty subunit 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_BRUA4
Sequence: MSRRHKAEKREINPDPKFGDLVITKFMNAVMLHGKKSVAESIVYGALDVIEAKAKSEPVALFHQALDNVAPHIEVRSRRVGGATYQVPVDVRPERRQALAIRWLINAARGRNETTMIDRLSGELLDAANNRGSAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS7_MAGMM
Sequence: MSRRREVPKREVIPDARYNDKLVAKFMNCLMVDGKKSLAERVFYGAFDLIEQRTKEDPIKVFKEAVDNVRPTLEVRSRRVGGANYQVPVEVRPVRRQTLAIRWLIGYARSRGEKTMRERLAAELIEASQGRGATIKKRDDTHRMAEANKVFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.