PharMolix/UniProtQA huggingface dataset:
Protein: RPO3_HALMA
Sequence: MTQDYEVEFVERGEREARILVRGITPAFANGIRRAMVADVPTFSIDTVRVIENTSVMFNEQIGLRLGLVPLTTDLDDFEIGDEVTLSLSVDGPSTAYSSDLVSSDPMVEAADDNIPIIDLKEGQRLEVEADAVLDTGREHAKHQGGVAVGYRHLQQVEVVGDLGEFEDDDPNILRGVIEEQAAEHAAGDATNGELVATDEFDNDLRNRYPGKDVEVSDVPNAFVFHVETDGSFTTEELVLRAVETLRDRATELKDAVQL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo3, DNA-directed RNA polymerase subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSK22_BACSU
Sequence: MHLTLQSVYPAIIIIFFLYKKIKRSIGYQPLKPRWLFTRIILFSLFAFGLSIFSAIHPFLYGYLILGILGGWLLVFFAKKNISFEKRRGKIYFRTHIWVEVILLTLFLSRFLYRVTELYLTSPDLNRLGSYSQSIGTDPLTIGVCFLIAVYYIGFSSFIIKLSRNELEQHEYNKEKDILAR
What are the official names of this protein?
Protein csk22.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BCHN_ACIRU
Sequence: MSVCTTAPSATAPDIIRQRGQRTVFCGLTGIVWLHRRIQDAFFLVVGSRTCAHLVQSAAGVMIFAEPRFATAIIEERDLAGRADLDDELDRVVTRLIERRPDIKLLFLVGSCPSEVIKLDLTRAAARLDERFGRLPRILAYSGSGIETTFTEGEDACLEALVPTLADAGSTTSLMVVGAVADIVEDQFRRLFTAIGIERVDFLPARHAGAMPAVGPHTKFILAQPFLAATARALHERGARRIAAPYPLGAEGTRLWIEAAAAAFGIDPARTESVLALPARRATESLAAVRAKLAGRKIFFFPDSQLEIPLARFLARECGVELVEVGTPFLHRDLMDAELALLPFATQLSEGQDVERQLDRCRAEQPDLVICGLGLANPLEAEGIATKWSIELVFSPIHGFEQAADLANLFARPLARRALLSV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: KTHY_CHLL2
Sequence: MLITFEGIDGAGKSTQIRKLQKLLIGAHIDSITLREPGGTEVAEKIRQILLESRHEISPIGELLLFSASRAELVQQVILPAIDNGTTVILDRFFDSTIAYQGYGREIDQVMLQTIITLSTFSLQPDITFYLDISPENALMRKFSEKSLPIAFDESELDRMERSGLDFFRKVRQGYLDIIHKNERRFVLLDALDDPQMIHKRIIASLKERFPVFSGIKTR
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NP03_HHV1F
Sequence: MVKPLVSYGSVMSGVGGEGVPSALAILASWGWTFDTPNHESGISPDTTPADSIRGAAVASPDQPLHGGPEREATAPSFSPTRADDGPPCTDGPYVTFDTLFMVSSIDELGRRQLTDTIRKDLRLSLAKFSIACTKTSSFSGNAPRHHRRGAFQRGTRAPRSNKSLQMFVLCKRTHAARVREQLRVVIQSRKPRKYYTRSSDGRLCPAVPVFVHEFVSSEPMRLHRDNVMLASGAE
What are the official names of this protein?
Nuclear phosphoprotein UL3.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL3 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: AAEB_ECOL5
Sequence: MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELKIYQEKLRIWQAPPQVTEPVHRLTGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRF_PENCH
Sequence: MSSKSQLTYTARAQSHPNPLARKLFQVAEEKKSNVTVSADVTTTKELLDLADPSTGLGPYIAVIKTHIDILSDFSQETIDGLNALAQKHNFLIFEDRKFIDIGNTVQKQYHNGTLRISEWAHIINCSILPGEGIVEALAQTAQATDFPYGSERGLLILAEMTSKGSLATGAYTSASVDIARKYPSFVLGFVSTRSLGEVESTEAPASEDFVVFTTGVNLSSKGDKLGQQYQTPQSAVGRGADFIISGRGIYAAADPVEAAKQYQQQGWEAYLARVGAQ
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: GLN1B_MYCS2
Sequence: MAEKTSDDIFKLIKDENVEYVDIRFCDLPGVVQHFSIPASAFDESVFEDGLAFDGSSVRGFQSIHESDMMLLPDPNTARIDPFRAAKTLNMNFFVHDPFTREAYSRDPRNVARKAENYLASTGIADTAFFGAEAEFYIFDSVSFDSKINGTFYEVDSESGWWNTGEPFESDGSANRGYKVRPKGGYFPVAPYDHYVDLRDQMATNLQNAGFTLERGHHEVGTAGQAEINYKFNTLLAAADDVLLFKYIIKNTAWQAGKTVTFMPKPLFGDNGSGMHAHQSLWKDGQPLFHDESGYAGLSDIARHYIGGILHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGNNPKAKRLEFRCPDSSGNPYLAFAAMLMAGIDGIKKKIEPLQPVDKDLYELPPDEAAAIPQAPTSLSAVIDKLEEDHEYLTEGGVFTEDLIETWISYKRENEIMPIQIRPHPYEFSLYYDV
What is the function of this protein?
Involved in nitrogen metabolism via ammonium assimilation.  Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_PASMU
Sequence: MMRILLFLATNMAVLVVFNIILSLTGIQAQDATGLLLMAALFGFSGSLISLFLSKTMALRAVGAEVIKQPRNDMERWLVNTVRSQAERANLPMPDVAIYHSEDVNAFATGPSKNNSLVAVSTGLLRAMTQDEAEAVLAHEVAHIKNGDMVTMTLLQGVLNTFVIFVSRMIAKVVSSNRDGESSTGIYFLVSMVLEILFGFLASMIAMWFSRYREFRADAGSAKLVGKHKMIAALQRLQRLHEPQELEGQLAAFAINGKRGGLAALFMSHPPLEKRIAALQQLDSFK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDRP1_LISMO
Sequence: MTQPAVYVVSDSTGETAELVTRAALSQFGQTPKFIHRFHHVDSSHMIEEIVDLVAVNNGIIVHTIVLESVREELNKTAQAFGVPIIDLFGPLLNQLEETYKIKPLSEPGRVRSMDEAYFNKVAAIEFAVENDDGRNPRGILQADYVLIGISRTSKTPLSQYLALKGLKIVNIPIVPEAQIPDELFEIDPKKIIGLKISKQKLTKIRQERLISIGLPGAGTYASNQRIDEELAIFNKLASKLNCFVLDVTNKAIEETANEILIHIGEIVDENLEL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 1, PPDK regulatory protein 1.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: KUP_PSEF5
Sequence: MGQASSQAASGEHSGVKPLGMLVAAVGVVYGDIGTSPLYTLKEVFSGSYGVQVNHDGVFGILALIFWSLVWVVSIKYVLFILRADNQGEGGIMALTALARRASASYPRLRSVLVILGLIGASLFYGDSMITPAISVLSAVEGLELAFSGLEHWVVPLALVVLVALFLIQKHGTDRIGKLFGPVMVAWFLVLGGLGINGILQHPEVLQALNPVWGVRFFIVHPGMGVAILGAVVLALTGAEALYADMGHFGRKPIARAWFALVLPALVLNYFGQGALLLENPEAARNPFYLLAPGWALIPLVVLATLATVIASQAVISGAFSLTRQAIQLGYIPRMHIQHTSSAEQGQIYIGAVNWSLMVGVILLVLGFESSGALASAYGVAVTGTMLITSILVAAVMLLLWKWPPVLAVPVLLGFLLVDGLFFAANVPKIFQGGAFPVLAGIVLFILMTTWKRGKELLVDRLDEGGLPLPIFISSIRVQPPHRVQGTAVFLTARPDAVPHALLHNLLHNQVLHEQVVLLTVVYEDIPRVPANRRFEVDSYGEGFFRVILHFGFTDEPDVPEALKLCHLDELDFSPMRTTYFLSRETVIASKLVGMARWREALFAFMLKNANGNLRFFKLPVNRVIELGTQVEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1336_AQUAE
Sequence: MKPKVRFFDLQPYGDKFVVRDPVGISQPFIATPELLFLLSLMDGTRDITDLQAEFFKKTGHLIPKEEINQVINFLDENYLLYNERFLNKLKEEREKILKKGYREPSHAGQAYPENPQELKNFIEETVNKNSEKFKARGILVPHMDLRVASGVYGSVYSAIKENEYDTVVLLGVSHYFHETPFSVLPLDLRTPLGDLKVDIERVEELQKMFDYDLSHDVLAYKNEHSIEFQTIFLKYLFPEVKVIPAIVSYGDTKSLKEIAHKITKVLEDSQNPLIISSVDFSHVGRKFGDPHSYDPSPRDREYINLLAELKNEEAFNLLQSDNNRTRIDGQFTNFVFLEILKNLGVKEGKLLDYDVYHEAPTDSKVSYAGMVFY
What are the official names of this protein?
MEMO1 family protein aq_1336.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: TDXH_METTM
Sequence: MPLIGDKFPEMEVQTTHGLMKLPAEFKGRWFILFSHPADFTPVCTTEFVAFQEVYPELRELDCELVGLSVDQVFSHIKWIEWIEENLDTEIEFPVIADTGRVADTLGLIHPARPTNTVRAVFVVDPEGIIRAILYYPQELGRNIPEIVRMIRAFRVIDAEGVAAPANWPDNQLIGDHVIVPPASDIETARKRKEEYECYDWWLCHRSASGD
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEMP_CVBLY
Sequence: MFMADAYFADTVWYVGQIIFIVAICLLVIIVVVAFLATFKLCIQLCGMCNTLVLSPSIYVFNRGRQFYEFYNDVKPPVLDVDDV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: FUCT1_HUMAN
Sequence: MNRAPLKRSRILHMALTGASDPSAEAEANGEKPFLLRALQIALVVSLYWVTSISMVFLNKYLLDSPSLRLDTPIFVTFYQCLVTTLLCKGLSALAACCPGAVDFPSLRLDLRVARSVLPLSVVFIGMITFNNLCLKYVGVAFYNVGRSLTTVFNVLLSYLLLKQTTSFYALLTCGIIIGGFWLGVDQEGAEGTLSWLGTVFGVLASLCVSLNAIYTTKVLPAVDGSIWRLTFYNNVNACILFLPLLLLLGELQALRDFAQLGSAHFWGMMTLGGLFGFAIGYVTGLQIKFTSPLTHNVSGTAKACAQTVLAVLYYEETKSFLWWTSNMMVLGGSSAYTWVRGWEMKKTPEEPSPKDSEKSAMGV
What is the function of this protein?
Antiporter specific for GDP-l-fucose and depending on the concomitant reverse transport of GMP.  Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-fucose transporter 1, Solute carrier family 35 member C1.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CYB6_POPAL
Sequence: MSKVYDWFEERLEIQTIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLGVLTASFGVTGYSLPWDQIGYWAVKIVTGVPEAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFPMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SLMA_EDWI9
Sequence: MAEKENTKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTRMFDSLIEFIEDTLTSRINLILQDEKDTFHRLRLILLLILGFAERNPGLTRIMTGHALMFEQDRLQGRINQLFERIEAQLRQVLKERRLREGSGFDHDETLLASQLLAFCEGMLSRFVRSEFRYRPTQEFETRWPLLACQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KLK3_MACMU
Sequence: MWVLVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRSNSVILLGRHNPYYPEDTGQVFQVSHSFPHPLYNMSLLKNRYLGPGDDSSHDLMLLRLSEPAEITDAVQVLDLPTWEPELGTTCYASGWGSIEPEEHLTPKKLQCVDLHIISNDVCAQVHSQKVTKFMLCAGSWMGGKSTCSGDSGGPLVCDGVLQGITSWGSQPCALPRRPSLYTKVVRYRKWIQDTIMANP
What is the function of this protein?
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
What are the official names of this protein?
Prostate-specific antigen, PSA, Kallikrein-3, Semenogelase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_PROMH
Sequence: MSNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRENVVSIIANGVVLSPEALMKEMTQLEERGIPVRSRLLLSEACPLILPYHIALDNAREKARGEKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKKAFAQKLKEIIEYHNFQLVNYYKVEPVDYQKTLDDIMAIADILTGMVVDVSDLLYKATQKGELVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVGYVLGIIKAYSTRVGAGPFPTELFDETGDFLREKGQEFGATTGRSRRTGWLDIIAIRRAVQINSLSGFCMTKLDVLDGLKEVKVCVGYRLPNGEVIETTPLAADDWEGIEPIYESMPGWNESTFGVKDKAQLPQAALNYIKRVEELTGVPVDIVSTGPDRSETIILRHPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2CB_BOVIN
Sequence: EAKDDLARLLRDYQDAMNVKLALDVEIATYRKLLEGEECRMSGECPSAVSISVVSSSSTTSASAGGFGGGYGGGVGVGGGARSGFGGGSGFGGGSGISGSSGFGGGSGSGFGGGSGFSGSSGFGGGSSGFGSGSGGRSGVSGGGLSSGSSRGGSVRFSQSSQRTSR
What are the official names of this protein?
Keratin, type II cytoskeletal 68 kDa, component IB.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: GUNB_CLOC7
Sequence: MNKRLSRGKISLLASVFVTTTFMGGVNVLASTAKTGIRDITSQQVVKEMKVGWNLGNTMDATGGETNWGNPLTTHAMIDKVKAAGFNTLRLPITWDGHIGAAPDYAIDATWMNRVEEIANYAFDNNMYVIINLHHEDGWLKPYYANEAEVKAKITKVWTQIANRFKDYGDYLIFETMNEPRPVGAADEWSGGSYENRDMVNRYNLTAVNTIRATGGNNALRHIMVPTLAAAALSTTMNDYIVPNNDSRVIVSLHMYSPYFFSADLTSQWTTATWGSDADKAALSADFDAVYNKFVKNGRAVVIGEMGTINKNNLDSRVKHAEYYAKEATVRGITPIWWDNGYCVAGKEQTFGIFNRKNLTWCCPEVMQAFIRGAGATQTQTSYSLGDVNKDGKVNAIDYAVLKSILLGTNTNVDLSVSDMNKDGKVNALDLAVLKKMLLS
What is the function of this protein?
Has endoglucanase activity on carboxymethyl-cellulose (CMC), xylan and lichenan, but not Avicel.
What are the official names of this protein?
Endoglucanase B, Cellulase B, Endo-1,4-beta-glucanase B, Endo-1,4-beta-xylanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: TAF1D_RAT
Sequence: MAQSEVDSVDCVTSDRDGDIGNQSDDSSNSSLFKTQCVPSPTRKQRIPTVKCVPSLASVETDSSSDSSLEPRPLTLKAIFERFKKKKRKKRKKRKYKPKLRRQGRPSGTRNIRRSQIDAKQIKDKGAVFPFLESESGRKTLPWKKILTYEQAVARGFFHHIEKLKYEHHLKECLSQMHAGEDLEKEDFDSRRHKYMDDDGPLSPIEEPSTEDEATDPQSECDIKLVEDSCFIISTEFPRKRNLEQGKIKKESAFSKKSKAKDATQRGNRRSWKGGEHACLHSEVS
What is the function of this protein?
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription.  The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter.  SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.  Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits (By similarity).
What are the official names of this protein?
TATA box-binding protein-associated factor RNA polymerase I subunit D, TATA box-binding protein-associated factor 1D, TBP-associated factor 1D, Transcription initiation factor SL1/TIF-IB subunit D.
What are the subcellular locations of this protein?
Nucleus.
Protein: BL1S1_YEAS1
Sequence: MFLTFSMCVNWIIVKMPNRSEELDRLLDKIINSPHRTEASKTLQEIENNQSYILNVQLKKLLRLHDDSFKNKCVSPINYMLEKYTPYMGHTEALQKEAELVDRDLRILEMTYQLIEKNRNSK
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLS1, BLOC-1 subunit BLS1, BLOS1-homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: SYK_PROM3
Sequence: MARSVLSALSELRETRLEKAQALKELGNGPYALRFESSHRTANLQADHADLAKGEERLLSVSVAGRVMARRVMGKLAFYTLADETGTIQLYLDKATIDAAASNELASGTFVQLTTLVDAGDWIGVTGVLRRTDRGELSVKVQQWQILSKSLQPLPDKWHGLADVEKRYRQRYLDLIVSPQSRETFRRRALMVSAIRRWLDDRAFLEIETPVLQAEAGGAEARPFITHHNTLDLPLYLRIATELHLKRLVVGGFERVYELGRIFRNEGMSTRHNPEFTSVEVYQAYADYIDMMVLTEQLISSVCTQICGSTRITYQGIEIDLTPPWRRASMHELVQEATGLDFMGFADRAVAASAMARAGLEVPSKADSVGRLLNEAFEQAVEVSLIQPTFVLDYPIEISPLARQHRSKPGLVERFELFIVGRETANAFSELIDPLDQRQRLEAQQARRQAGDLEAHGVDEDFLQALEVGMPPTGGLGIGIDRLVMLFTDSPSIRDVIAFPLLRPELKT
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP88_RAT
Sequence: MAAAAGPVGDGELWQSWLPNHVVFLRLREGLKNQSPAEADKPATSTSPSCPPLPPHLPTRNLVFGLGGELFLWDAEGSAFLVVRLRGPSGGSVEPPLSQYQRLLCINPPLFEIHQVLLSPTQHHVALIGTKGLMALELPQRWGKDSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAWYPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLVTVSKNMFEQKDREAVAYPLYILYENGETFLTYVSLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEDDDQTLEKSWDPRADLIPSLYVFECVELELALKLASAEDDPFASDFSCPIKLHRDPKCPSRYHCSHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELTAEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLCTREDAGVAESPLRILAEAPDSFEKHIKRILQRSAANPALLKSSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKRKQLEDLNYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHTQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
What is the function of this protein?
Component of nuclear pore complex.
What are the official names of this protein?
Nuclear pore complex protein Nup88, 88 kDa nucleoporin, Nucleoporin Nup84, Nucleoporin Nup88.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.
Protein: RL18_HAHCH
Sequence: MSDKKISRLRRAKKTRYKIRELGVDRLSINRTPRHIYAQIISADGSKVLATASTLDKDLRAGATGNVEAAGKVGAMIAERAKAAGITKVAFDRSGFKYHGRVKALADAARENGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DNSL3_RAT
Sequence: MSLYPASPYLASLLLFILALHGALSLRLCSFNVRSFGESKKENHNAMDIIVKIIKRCDLILLMEIKDSNNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFLYKEKLVSVKAKYLYHDYQDGDTDVFSREPFVVWFQAPFTAAKDFVIVPLHTTPETSVKEIDELADVYTDVRRRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPNFVWLIGDQEDTTVKKSTSCAYDRIVLRGQEIVNSVVPRSSGVFDFQKAYELSEEEALDVSDHFPVEFKLQSSRAFTNSRKSVSLKKKKKGSRS
What is the function of this protein?
Has DNA hydrolytic activity.  Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends (PubMed:7957253).  Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA.  Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis.  The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells.  Is active on chromatin in apoptotic cell-derived membrane-coated microparticles and thus suppresses anti-DNA autoimmunity (By similarity).  Together with DNASE1, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity).  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity).  Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation (By similarity).
What are the official names of this protein?
Deoxyribonuclease gamma, DNase gamma, DNaseY, Deoxyribonuclease I-like 3, DNase I-like 3.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Nucleus. Secreted. Note=May first pass through the ER membrane before being imported in the nucleus. Contradictory reports exist about the subcellular localization under normal physiological conditions. Under conditions of cell death, may diffuse and/or be actively transported to the nucleus (By similarity).
Protein: SYE_LATSS
Sequence: MAKNKIRVRYAPSPTGHLHIGNARTALFNYLFARHNKGTFVIRIEDTDTKRNIADGENSQLDNLKWLGMDWDEGPDKPGNYGPYRQSERREIYTPLIQELVEKGLAYESYKTEDELTAEREAQKAAGEAPRYVYEYEGMSDDEIKASQEAARAKGLQPVVRLRLPKDHVYKFDDIVKGEISFESDRLGGDFVIMKRDGMPTYNFAVVVDDHLMEITHVLRGDDHIANTPKQLAVYEAFGWEPPIFGHMTLIINTETGKKLSKRDESVLQFIEQYRELGYLPEAMFNFIALLGWSPVGESELFNRQEFIKQFDPRRLSKSPASFDQKKLEWVNNQYVKQSDPNKIMDLSLDSLIKAGKIAANPDSKTIEWARHLIALYQDQMSYTAQIVEMSDVFFEEPEQLDAEALEELNNETAPVVLKEFSERLKDLTLFTAPRIMQIIKGIQKDTKIKGRLLYMPIRIATTREMHGPSLPDSIELLGKDRVLAHLEKTLAEIK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM19_RECAM
Sequence: MLNLIQTLRMEATQKSRHKKTQIQSGDILSITTTQYKNKKRKQNLKGICIGIKKRIGYTTIQLRNFIGGVSQEQSFILESPIINNIEIIGKIKGNTKAKKYYLRTKSPSENKV
What are the official names of this protein?
60S ribosomal protein L19, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
What are the subcellular locations of this protein?
Mitochondrion.