PharMolix/UniProtQA huggingface dataset:
Protein: CAHM5_RAT
Sequence: MDAFQSILKFFLNQKTAIGYSFMALLTVGSERLFSLVAFKCPCSIENTAYGLVFLFAPAWVLLILGFFLNNKAWRLFTGCCMNPQKIFPRRRCCRFFYVLGHITLSSLVAPVMWLSVALLNGTFYECAMSGTRSTRLLEMICKGKPKECWEELHKVSCGKSSMAAMDSEEVRLSLQAQSQILGWCLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQREKEQLENKLLEYANKLSERNLKCFFENKKPDPFPMPSFAAWEAASELHSFHQDREHYSTLHKVVDDGLEQTPQEEETTMILVGTAQSL
What is the function of this protein?
Pore-forming subunit of a voltage-gated ion channel.
What are the official names of this protein?
Calcium homeostasis modulator protein 5, Protein FAM26E.
What is the protein family that this protein belongs to?
Belongs to the CALHM family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FAIM1_RAT
Sequence: MASGDDSPIFEDDESPLCSLEKMTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRREWMFKLVGKETFFVGAAKTKATINIDAISGFAYEYTLEIDGKSLKKYMENRSKTTNTWVLHLDGEELRVVLEKDTMDVWCNGQRMETAGEFVDDGTETHFSVGNHDCYIKAVSSGKRREGIIHTLIVDNREIPELTQ
What is the function of this protein?
Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.
What are the official names of this protein?
Fas apoptotic inhibitory molecule 1, rFAIM.
What is the protein family that this protein belongs to?
Belongs to the FAIM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPAA_PENRF
Sequence: MVGSMENPGSWGLACLLISTSRFNRYMPYYTMMAAVWSTLIAGALKLQEDPASLSVEYILFKAGLCFVHCLLLCGAGNTWNDLIDRDIDARVERTKMRPLASGKVSTVEALVWMVGQYFLSVKMLDLILDNRSIWGLMLPLTASIMLYPYLKRPVFSRVFIYPQYILGLAVAYPSITGWASINGQEQSMSEIFTHCTPICLLIFFWCLYFNTAYSHQDSVDDRKMNINSAYVVAGQRIRLFLAFLGALPLAVIPYVVLKINSPWLWFSWMAVWTVSIVMQIVRFDSKKLESGGRIHWDNFLLGLWTTVACIVEVGLQKVEFWNLI
What is the function of this protein?
Polyprenyl transferase; part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 (PubMed:26751579).  MpaA is a Golgi apparatus-associated enzyme that catalyzes the prenylation of 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) to yield farnesyl-DHMP (FDHMP) (PubMed:26751579).  The first step of the pathway is the synthesis of 5-methylorsellinic acid (5MOA) by the cytosolic polyketide synthase mpaC.  5MOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) by the endoplasmic reticulum-bound cytochrome P450 monooxygenase mpaDE.  MpaDE first catalyzes hydroxylation of 5-MOA to 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid (DHMB).  MpaDE then acts as a lactone synthase that catalyzes the ring closure to convert DHMB into DHMP.  The next step is the prenylation of DHMP by the Golgi apparatus-associated prenyltransferase mpaA to yield farnesyl-DHMP (FDHMP).  The ER-bound oxygenase mpaB then mediates the oxidative cleavage the C19-C20 double bond in FDHMP to yield FDHMP-3C via a mycophenolic aldehyde intermediate.  The O-methyltransferase mpaG catalyzes the methylation of FDHMP-3C to yield MFDHMP-3C.  After the cytosolic methylation of FDHMP-3C, MFDHMP-3C enters into peroxisomes probably via free diffusion due to its low molecular weight.  Upon a peroxisomal CoA ligation reaction, catalyzed by a beta-oxidation component enzyme acyl-CoA ligase ACL891, MFDHMP-3C-CoA would then be restricted to peroxisomes for the following beta-oxidation pathway steps.  The peroxisomal beta-oxidation machinery than converts MFDHMP-3C-CoA into MPA_CoA, via a beta-oxidation chain-shortening process.  Finally mpaH acts as a peroxisomal acyl-CoA hydrolase with high substrate specificity toward MPA-CoA to release the final product MPA (PubMed:26751579) (Probable).
What are the official names of this protein?
Polyprenyl transferase mpaA, Mycophenolic acid biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Note=Membrane association is functionally relevant because mpaA must ostensibly interact with its membrane-embedded substrate FPP.
Protein: LEXA_GEOSM
Sequence: MEQLTARQTEVLQIITRHLETCGYPPTLREIAAKLGISGTLGVMKHLEALEKKGYLRRQEGSTRGITLCNQNQATSLPIVGVVRAGLLHPAIQDIEGHFAIDRSQLASGGAFFLRVKGDSMIHAHIVEGDLALVRPQPDASNRDIVVAMVEGEATLKRFYREADRIRLQPENPNYEPIIIQKGEQEVSIVGKVVGIYRQME
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL9_VIBVY
Sequence: MQVILLDKIGNLGSLGDTVNVKSGYARNFLIPQGKAVMATKGNVEMFEARRAELEAKVAEQLASAEARAEKVNALEAVVIASKAGDEGKLFGSIGTRDIADAITAAGVEVVKSEVRLPEGALRTTGEFEISVQLHSEVFATVKLQVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RL4_METKA
Sequence: MEAPVFNLEGEEVDTVELPSFFEEPVRKDLIRRAVLAAQANRRQPYGTDPRAGFRTSAESWGAGHGVAMVPRVKGRRHPAAGRAARVAQAVGGQKAHAPTPEKDWTQRVNRKERRAALRSALAATAKPEFVKERGHVIDDVPHLPVVVVDELKSLNKAREVREFFKSVGLWADVERAKSNRRIRAGKGKRRGRRYVKPKSVLIVVDEDEGIKLGARNHPGVDVVEAMHLGVEHLAPGAHPGRLTVFTPGALEVLEERLGE
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y4396_MAGSA
Sequence: MSDLHSSPTDQTSAPAHAGGGNRVVIVTGMSGAGKTMALKALEDMGWEAVDNLPLALAASLVRSGGGMARPLALGVDIRTRDFGVEPVLAALDHLMGESGLDVRLLFLDCEDDVLCRRFTETRRRHPMAVDRPLLDGIRHERALVSPLKRRADVMIDTTNQPPGEFKRLLAGHFGLESNGGLGVFVTSFAYRNGLPREADLVFDARFLANPHYVPELKPLTGRDPAVAQYVAADPAFGPFIESLTRLLEPLLPRFAAEGKSYLTIAVGCTGGRHRSVAIAEHLAQWMQRRGGKVELRHRELDERGS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein amb4396.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: YHFA_ECO57
Sequence: MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAAGGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVARAVDLSAEKYCSVALMLEKAVNITHSYEVVAA
What are the official names of this protein?
Protein YhfA.
Protein: RPOB_SACEN
Sequence: MAVSRATKVSAASNMMSGIPGAPKRVSFANIREPLEVPDLLDLQVQSFEWLVGDETWFQRRVDAGDENPVGGLEEVLSEISPIEDFSGSMSLSFSDPRFDEVKASVEECKDKDMTYAAPLFVTAEFTNHTTGEIKSQTVFMGDFPVMTDKGTFIINGTERVVVSQLVRSPGVYFDQSVDKTTDKDVYSVKIIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTAEAIRERFGFSETLMATLEKDHTAGQDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLDLPFESGVLTEEDIVTTIEYLVRLHAGEAEMPDRGQGGDATIPVEVDDIDHFGNRRLRTVGELIQNQVRVGLSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQTNPIAGLTHKRRLSALGPGGLSRERAGMEVRDVHPSHYGRMCPIETPEGPNIGLIGSLATFARVNPFGFIETPYRKVVDGRVTDQIDYLTADEEDRFVKAQANTPIDDEGNFLADRVLGRRKGGEVELLAPTEIDYMDVSPRQMVSAATAMIPFLEHDDANRALMGANMQRQAVPLLRSEAPLVGTGMELRAAVDAGDVVTAEKAGVIEELCADYITVMADDGTRRTYRLQKFSRSNHGTCTNQKPIVNEGDRVEAGQVIADGPCTQNGEMALGKNLRVAIMPWEGHNYEDAIILSQRLVQDDVLTSIHIEEHEVDARDTKLGAEEITRDIPNVSEDVLADLDERGIIRIGAEVQGGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGETGKVIGVRVFNREDDDELPPGVNELVRVYVAQKRKIQDGDKLAGRHGNKGVIGKILPAEDMPFTEDGTPVDIILNTHGVPRRMNIGQILETHLGWIASQGWSIDGDPEWAKRLPEELYDVDPGTNTASPVFDGAREEEITGLLASTKPNRDGERMVKANGKAQLFDGRSGEPYPYPVAVGYMYILKLSHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDVVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIEMRDGDDEDLERAAANLGINLSRNESPSVDDVVQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: LEUD_NEIG1
Sequence: MKAFTKITAIVAPLDRSNVDTDAIIPKQFLKSIKRSGFGPNAFDEWRYLDHGEPGMDNGKRPLNPDFSLNQPRYQGAQILLTRKNFGCGSSREHAPWALDDYGFRAIIAPSFADIFFNNCYKNGLLPIVLTEEQVDRLFKEVEANEGYRLSIDLAEQTLTTPGGETFTFDITEHRKHCLLNGLDEIGLTLQHADKIKAFEEKRRQSQPWLFNG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RS18_CAMC1
Sequence: MAEKRKYSRKYCKFTEAKIDFIDYKDTSLLKYCLSERFKIMPRRLTGTSKRYQEMVEKAIKRARHAAIIPYIVDRKNVVSNPFEGL
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RS17L_METAC
Sequence: MRDIGINGIKLPTEDCNDPECPFHGKLSVRGQILKGIVISDKMTKNIVMKRYREKWSYKYQRKQRVSSKIHAYSPPCMEAKIGDIITIAECRPLNKGSSFVVIENKSNINFVDNLLNVDDKWREELYVKDLKEMISLIQKEIKSLPSKSSELPIRLDQLANCQRNLYFISGDIKQLEDSVDNFSKSVSLTPINSSDKLIRLISLGKTQSFLYKTTNDVSSLDSAINAYGEAIETYNVLSTITNNYLPYFLTASKNLADLLIFEYEKNKNASDLKRAVYYYNEFLNSAPTGTSNTPIVLKRLSSAMKYYYTLNQDIDYLEKEINYIQKAVNITNSSSANLPGLLIDLGDSLNEYYECGKSKIPFDKLEKILIESRNSYMKAKGLISDDSINLLKIFNNIGNVSRELYIHTNEISYLKEAIDFWRKSIKSEDLNKQNYSSNNILRLNNLAVGLIDLYEVESDPKYLDESQKIWNRLKRELWTRKNYKS
What are the official names of this protein?
Putative 30S ribosomal protein S17-like protein.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PHNO_ECOLI
Sequence: MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRDPNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL
What is the function of this protein?
Aminoalkylphosphonate N-acetyltransferase which is able to acetylate a range of aminoalkylphosphonic acids, including aminomethylphosphonate, (S)-1-aminoethylphosphonate and 2-aminoethyl- and 3-aminopropylphosphonate, using acetyl-CoA as acetyl donor.  Is required for the utilization of aminomethylphosphonate and (S)-1-aminoethylphosphonate as a phosphate source via the C-P lyase pathway.  Is also essential for the detoxification of (S)-1-aminoethylphosphonate, a structural analog of D-alanine that has bacteriocidal properties due to inhibition of cell wall synthesis (PubMed:23056305).  Also acts as a N-epsilon-lysine acetyltransferase that catalyzes acetylation of several proteins (PubMed:30352934).
What are the official names of this protein?
Aminoalkylphosphonate N-acetyltransferase, KAT, Peptidyl-lysine N-acetyltransferase.
Protein: SYD_XANCP
Sequence: MRTHFCGLVDETLIGQTVTLAGWTDVARNLGGVCFIDLRDHEGIVQVTVEPAEGDANSAEVFKVAASLGYEDVLQVEGVVRARHAVNDKIRTGKVEVIATRITILNKAAPLPFHAHENPGEDTRLKYRYLDLRRPEMQRMQRTRIKLVQALRRHLDARDFQDIETPILTKATPEGARDFLVPARMHPGEFYALPQSPQLFKQILMVAGFDRYYQIARCFRDEALRADRQLEFTQLDMEFAFVRERDVQDFVEDMIRAIFKEVVDVELAAQFPRMTWAEAMRRYGSDKPDLRIALELVDVAELVKTSEFPVFAAAANDADGRVAALRIPGGATLSRKQIDDYAAHAAKYGAKGLAYSKLSETGEVSSPIAKFFGEEAFAALLAHVGAANGDIVFFGAGSYNKVSDFMGALRLKAGKDFGLVAAGWAPLWVTDFPMFEWDEEAQRYVALHHPFTAPAVDDIADLRANARTAVSRGYDMVLNGNEIGGGSIRIHRPDMQSAVFELLGIGAEEARAKFGFLLDALNYGAPPHGGIAFGIDRIAALMAGTESIRDVIPFPKTTGAQDLMTDAPSPIAAEQLAEVHVQVRPKQA
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24E_METAC
Sequence: MEQRKCYFCGKMLEPGTGKLYVKKDGSTYFMCSSKCMSNFALGRLPRRTEWTEKGKIQLKKA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: X_HBVB3
Sequence: MAARLCCQLDPARDVLCLRPVGAESRGRPLPGPLGALPPASPPIVPSDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHWNLPKVLHKRTLGLSAMSTTDLEAYFKDCVFTEWEELGEEFRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: GLO2_SYNE7
Sequence: MRIDCLPALQDNYIFLLVDVEQRQAAVVDPAEAEPVLAALQAEGLTLTAILNTHHHGDHVGGNRRLLRQFPEAAVSASAVDRDRIPGQTVLLEAGDRLQICGQTAEVLFVPGHTRGHIAYYFPEVAEGNPRGALFCGDTLFAGGCGRLFEGTPAQMLDSLQQLRSLPDDTAIYCAHEYTLNNLRFALTVEPDNFDLQQRYQAVAIARQQGQATIPSRLDIEKATNPFLRWDQAALQAAVSSQDPVQTLARLRSRKDQF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: DAPE_MANSM
Sequence: MKNTIINLAQDLIRRPSISPDDQGCQQVIAERLTKLGFNIEWMSFNDTINLWAKHGTTSPVVAFAGHTDVVPTGDENQWNYPPFSAQIVDDMLYGRGAADMKGSLAAMIVAAEEYVKANPNHAGTIALLITSDEEAAAKDGTVKVVESLMARGENIDYCLVGEPSSAKQLGDVVKNGRRGSITGDLYIQGIQGHVAYPHLAENPVHKATKFLTELTTYEWDNGNEFFPPTSLQIANIHAGTGSNNVIPGELYVQFNLRYCTEVTDEFIKNKVAEMLQKHDLTYRIDWNLSGKPFLTKPGKLLNAVVESLESVAGIKPKLDTGGGTSDGRFIALMGAEVVELGPLNATIHKVNECVSCRDLATLGEVYRQMLVNLLGK
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RS6_SALHS
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYSAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TIG_LEPBL
Sequence: MDYKTKKNSNATVDIKLTFEASDLEKAFDKTYAEKQKNIKIPGFRPGKAPLNMVKRHLGDTVASDAINTLIVDGMASILTKLEHPMVRFPKFEIQDYQPGKNLIATAVYETNPEITLGKYKKIKVKLPEVSVSDSDIFDEIENIRKQLARKQLKEDGQTAASGDIIDMEYTVCEKGQEPKNASNTSNDYHLGHENNLKGFDENLYGLGVGDRKEFSHTFPEDYLQNEVAGKTFEYSVTIKALYVNILPTVDDDLAAEFDGSDSLNTLKDKIRKNLKERFEEGIRNKKLEEIFKEIIDDSKYIFPDSYVKEESEHVFHNMIHEFKLPHITMEKYAKMIKKDLKEVQESFRNLAENRLKHFFTRQKIAEIENVTYTETDFDADLEKLASSYQIPLSDLKEELEKGKLMDQYRENFFAKKVDHTLFDLVEKKYTNKLSIGQVKDYLNQKEEQKV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: LFTR_NITMU
Sequence: MIPWLSSDSLFPPLHTALIQPNGLLAVGGDLSPRRLIEAYSQGIFPWFNDGDPILWWSPDPRMVLFPRELKVSRSLQKSLRKGNYEIRTDRNFTPVMRACAAPRRDSCGTWIQNKMIFAYSALHEMGFAHSVETWMDGELVGGLYGVALGRVFFGESMFSRVSNASKIAFVHLVRQLERWGFEMIDCQMKTAHLASLGAREIPREEFSQRLKELVNYMERGEKWCFDHEQVE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VC15_VACCC
Sequence: MSLESFIITTFNNNSSTNIDNMCHLYVKVCPSSLLFRLFVECCDINKLVEGTTPLHCYLMNEGFESSVLKNLLKEYVMNTFNVHDIHYTNI
What are the official names of this protein?
Protein C15/B21.
Protein: BLA13_KLEPN
Sequence: MRYIRLCIISLLATLPLAVHASPQPLEQIKQSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
What is the function of this protein?
Broad spectrum beta-lactamase which hydrolyzes penicillins, as well as cephalosporins except cephamycins.  Also hydrolyzes aztreonam, but not imipenem.  Confers highly resistance to ceftazidime, cefotaxime, aztreonam and piperacillin.
What are the official names of this protein?
Beta-lactamase SHV-13.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: PUR7_VIGAC
Sequence: RDSTTHQSHFRGGVGVTKISFKPHGFRAIRASVMPSEGQQQSSLGDSLVNSPHRNDVVDVIRKSAISNCLSETNLHNTVPGLVSKTRGKVRDIYDAGDYLVLVTTDRQSAFDRILASIPFKGQVLNETSLWWFERTKQIVPNAVVSAPDKNVTIAKKCSVFPVEFVARGFVTGSTDTSLWTVYNKGARNYCGNVLPDGMVKNQKLSENILTPTTKAADHDVPVTPDEIIERGLMTRSDYEEVSEKALSLFEYGQQVASEHGLILVDTKYEFGKANDGSIMLIDEVHTPDSSRYWIASSYPERFQNGLEPENIDKEFLRLWFKSHCNPYEDEVLPDAPEDLL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CRGA_MYCLE
Sequence: MPKSKVRKKNDFTITSVSRTPVKVKVGPSSVWFVTLFVGLMLIGLVWLMVFQLAALGTQAPTALHWMAQLGPWNYAIAFAFMITGLLLTMRWH
What is the function of this protein?
Involved in cell division.
What are the official names of this protein?
Cell division protein CrgA.
What is the protein family that this protein belongs to?
Belongs to the CrgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPE_VIBVY
Sequence: MTDSPVLALTKDLISRQSVTPEDAGCQDVMIARLEALGFTIERMVFEDTTNFWARRGTQAPLFAFAGHTDVVPAGKLEHWHTPPFEPTEKEGYLYGRGAADMKGSLAAMIVATERFIAEHPDHQGSIGFLITSDEEGPFINGTVRVVETLMARDENIDMCIVGEPSSTEVVGDVVKNGRRGSITGDLTVIGTQGHVAYPHLADNPVHKSLLAIHALATTEWDKGNEYFPPTSFQIPNVQAGTGASNVIPGEFHVQFNLRFSTELCNERIVERVTQTLDQHDLNYDLKWTYNGDPFLTDTGALLDAVVDAVDSVNQTKPALLTTGGTSDGRFIARMGGQVVELGPVNATIHKVNECVKIDDLEKLTDMYQKTLENLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: IF3_RALSO
Sequence: MRTFNIATEKSHRINREITAPEIRLTGVEGEQLGIVKLFDALRLAEEKDVDLVEIAPTAQPPVCRLMDYGKFKYQEQKKAHEAKLKQKVIQVKEVKFRPGTDDGDYEVKLRNLKRFLDEGDRTKITLRFRGREMAHQEIGARMLDRLKTDLEEFGQVEQMPKMEGRQMVMMLAPKKRK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRS11_ARATH
Sequence: MDKVMRMSSEKGVVIFTKSSCCLSYAVQVLFQDLGVNPKIHEIDKDPECREIEKALMRLGCSKPVPAVFIGGKLVGSTNEVMSMHLSSSLVPLVKPYLC
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides.
What are the official names of this protein?
Monothiol glutaredoxin-S11, AtGrxS11, Protein ROXY 6.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPS_BLOFL
Sequence: MILSQFDQNIQPLSSAILPRHIAIIMDGNGRWARGRGKLRIVGHQAGFQAARRAVRFAVHCRFNALTLYAFSSENWTRSNTEISSLMQLFIYALNSEINNLNKNNIKLRIIGDVNRFTQELQDCIYRSEQLTSNNNGLNLNIAANYGGRWDIVQGVKKIIAQIQKGVLKPNQINENILCKYVCMNELSPVDLVIRTGGEHRISNFLLWQIAYAELFFTDVLWPDFNDIVFRRALHSFMKRDRRFGKSAFI
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.