PharMolix/UniProtQA huggingface dataset:
Protein: PMGE_BOVIN
Sequence: MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSDGLQEARNCGKQLKALNFEFDLVFTSILNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALISLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYHEIYNDRKYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTVLISAQGNSCRALLKYLEGISDEEIINITLPTGVPILLELDENLRTVGPHQFLGDQEAIQAAIKKVDDQGKVKRADK
What is the function of this protein?
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG).  Also exhibits mutase (EC 5. 4. 2. 11) activity.
What are the official names of this protein?
Bisphosphoglycerate mutase, BPGM, 2,3-bisphosphoglycerate mutase, erythrocyte, 2,3-bisphosphoglycerate synthase, BPG-dependent PGAM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ACPH_ECO57
Sequence: MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYAALETRFWQFYPRMMAQASRKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: APOE_GRASU
Sequence: MKALWAVLLATLLTGCLSEGEPEVTEQLSWQSDQPWEQALNRFWDYLRWVQTLSDQVQEELQNSQVTQELTVLMEDTMTEVKAYKKELEEQLGPVAEETRARLAKEVQAAQARLGADMEDLRNRLAQYRNEVHTMLGQSTEELRSRLSSHLRKMRKRLMRDAEDLQKRLAVYKAGAREGAERGVSAIRERLGPLVEQGRQRTANLGAGVAQPLRDRAQALGDRLRGRLEEVGNQARDRLEEMREHMEEVRSKMEEQTQQIRLQAEIFQARLKGWFEPLVEDMQRQLANLVEKIQASTNSVLSTSVPQENQ
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: UL32_HHV7J
Sequence: MAYKGWNSDSFSMNSELFNEILLYAHLDSSGIDSDDLNTNPNTLENEINSVEKTLNIEELKKITTALNIDNRCNICSIINICLRHETDKMWIYDYALLCYKCNAAPRTPLAVVIIATEFMQLIQKHFLNINFDGLFLNNILSILDFHVHFFINRCFSNTNDDLLHNENITLYHMAILKSLLLEDESIPNIRIKKFKLKGKPTKKQHGNAILEKQTLPLNTHFTHLIFYMWAGTNIFDRISLTDLAIKKRQILKAIYSTKNELNCSAGPILLSQIPISITKNATSSVCLLCELMTSSQKNFDLLQFIYTSVINYCQNNLKMIDRIQFVLANLLDLARIYTNVKTTSDCSKIVLANEQEFSNSDFVIDCHSFLILKQVGPVGLYKHFFCDPLCIANIKTIKPHILFYTTESCILQDFKVAICYQNEYLNSVEKHVWLAIHFFKAFQVSKLNHKNKTLISDFLKDFTQLLADQNFEIVDPTFTIHYYV
What is the function of this protein?
Plays a role in efficient localization of neo-synthesized capsids to nuclear replication compartments, thereby controlling cleavage and packaging of virus genomic DNA.
What are the official names of this protein?
Packaging protein UL32.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL32 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Mainly cytoplasmic in transfected cell culture.
Protein: ANR39_HUMAN
Sequence: MATPRPCADGPCCSHPSAVLGVQQTLEEMDFERGIWSAALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNPRVVDDDGMTSLHKAAERGHGDICSLLLQHSPALKAIRDRKARLACDLLPCNSDLRDLLSS
What are the official names of this protein?
Ankyrin repeat domain-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the ANKRD39 family.
Protein: YVDG_VACCC
Sequence: MYEHRPPSLETNSFSSTRRLFSNSDWCCKDPGRSKLTNMVNSCTLLTIGVADKQIILWFFNAMVLDKKLYTERVGRILPSSLINDLEMKL
What are the official names of this protein?
Uncharacterized 10.4 kDa protein.
Protein: MINE_AGRFC
Sequence: MSIFSIFRKQKSAPLARERLQVLLAHERASSGTDLVAVLREEILSVIAKHVQIDNDRVHVKMDRDEHVSILEIDVEIPLGAHLRAA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: GLGB_BACLD
Sequence: MAGVSASDIKAHLFHEGRLYESYRFFGAHQTEQDGRQGFRFCVWAPHAKEVRIAGTFNGWSGVLHRMEKRHQEGIWELFIPGIGEGELYKYEMITAANETKLKADPYAFFSEVRPKTASVTYQLAGYQWGDRKWQKKKQQKAVYEKPISIYELHIGSWKKKADGRFFTYRELSETVIPYVKEHGFTHIELMPLTEHPFDRSWGYQTTGYYSPTSRYGEPHDLMYFIDQCHQHEIGVIMDWVSGHFCKDDHGLYLFDGMPLYEYKHEHDRENWEWGTANFDLGKREVHSFLISNALYWIEMYHIDGFRVDAVANLLYWPNRPQPEANGFAIEFIQTLNEQVFAKDPHFLMIAEDSTDWPLVTHPTYEGGLGFNYKWNMGWMNDVLTYMEASPEQRKHLHHLVSFSLMYAYSENYILPFSHDEVVYRKKSLLHKMPGDYWQKFAQYRLLISYFMMHPGKKLLFMGGEFAQFDEWKDEEELDWFLDDFDMHRKARMFTKEALHLYKKSRILYENDHRQQGFEWIDVNNAEQSIVSFIRYGKQPGEALIIVCNFTPSVYHEYRVGVPFQTEYIEVLNSDDAKYGGSHQINPKRLQARKGVLHGKPYSISMTVPPLGAAVFRAVKKRGAKKG
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: NECT1_PIG
Sequence: MARMGLAGAAGRWWGLALGLTAFFLPGAHTQVVQVNDSMYGFIGTDVVLHCSFANPLPGVKITQVTWQKATNGSKQNVAIYNPAMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPAGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGKDDKVLVATCTSANGKPPSVVSWETHLKGEAEYQEIRNPNGTVTVISRYRLVPSREDHRQSLACIVNYHMDRFRESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFRGPINYSMAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGQVPTAIIGGVVGSILLVLFVVGGIVVALCRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPEDSDDEKKAGPLGGSSYEEEEEEEGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV
What is the function of this protein?
Probably involved in cell adhesion.  Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells.
What are the official names of this protein?
Nectin-1, Herpes virus entry mediator C, Herpesvirus entry mediator C, HveC, Nectin cell adhesion molecule 1, Poliovirus receptor-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RR18_TOBAC
Sequence: MDKSKRPFLKFKRSFRRRLPPIQSGDRIDYRNMSLISRFISEQGKILSRRVNRLTLKQQRLITLAIKQARILSLLPFLNNEKQFERTESTARTTGFKARNK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCL_ECO57
Sequence: MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSELDNVMEFEDIADNAADAPTETCFMHYE
What is the function of this protein?
Catalyzes the condensation of two molecules of glyoxylate to give 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).
What are the official names of this protein?
Glyoxylate carboligase, Tartronate-semialdehyde synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: COBS_PSEPG
Sequence: MLPFLIALQFLSSLPVSLPGMPAAREVGRSLLYYPLVGLLFGLLLWLASHLLQGTPAPLHAALLLTAWVLLSGALHLDGLADSADAWLGGFGDRERTLQIMKDPRSGPIAVVTLVLVLLLKFCALWVLVEQGVGAQLLLAPLIGRTAMLGLFLCTPYVRPGGLGQALAEHLPRRAAGWVLLCCALFCLLLGGWVVLLAVAVFAWLRHLMYRRLGGATGDTAGALLELLELAVVLGLALGL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OCA2_SCHPO
Sequence: MSVTPPNVQFNLNGDSDHKSDNSSSSLENKLDTELKITSPPRNPPQRLHPVDFSEHADTDDDMNHPLPRVQSPVHIKNHIDPKLAEDRYRSSAARHFEPISIPPSAITSEDEDDYHGSANSSTVLPPRTENALHAASPKPSGSTGYTSPALSQNSGSGGEGESDEGSFNTQHHRSPIFQAYPSSEDLVGDPNDPYRRTRRAPIKTNPHDIPSQFIFRKLGLHHGKHGHHGHSGSLSLKSLVPNHHDKHDKHDKHEKHHSSLDLRRFFKSHQKTDKEKKPSVSKSKSSANLQDDHFGLFKKYGKFGRMLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETEREYARKVTAEFCIGSALHHTNIIETLDIVEENKKFYEVMEYAPYDMFSIVMSGKMTMPEVYCCFKQLLSGVAYLHSMGLAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETLVRKLYDPRAVDIWSSAIIFCCMALRRFPWKYPKLSDNSFRLFCMKQPSNDAESPSDILADIKKQRLVEQGCEPIRKTDESHSPNSKTDNSSTHKQELYGPWRLLRLLPRETRAVIAHMLELDPVKRYDIHRVFADNWINDISMCHMENGKVIHSPTHVHNLVASEESPAPPAKH
What is the function of this protein?
Overexpression causes cell cycle arrest.
What are the official names of this protein?
Serine/threonine-protein kinase oca2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Barrier septum. Cell tip.
Protein: SYWC_BOVIN
Sequence: MADMSNGEQGCGSPLELFHSIAAQGELVRDLKARNAAKDEIDSAVKMLLSLKTSYKAATGEDYKVDCPPGDPAPESGEGLDATEADEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELVNRIERATGQRPHRFLRRGIFFSHRDMHQILDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYGYAVENAKDIIACGFDINKTFIFSDLDYMGMSPGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDVQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTVEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRRDYTSGAMLTGELKKELIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSYDFQ
What is the function of this protein?
T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it.  T1-TrpRS and T2-TrpRS possess angiostatic activity.  T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells.  Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression (By similarity).
What are the official names of this protein?
Tryptophan--tRNA ligase, cytoplasmic, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANXA4_PIG
Sequence: MAAKGGTVKAASGFNAAEDAQTLRKAMKGLGTDEDAIISVLAYRSTAQRQEIRTAYKSTIGRDLLDDLKSELSGNFEQVILGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQLQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDMMDIRANFKRLYGKSLYSFIKGDTSGDYRKVLLILCGGDD
What is the function of this protein?
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
What are the official names of this protein?
Annexin A4, 35-beta calcimedin, Annexin IV, Annexin-4, Chromobindin-4, Endonexin I, Lipocortin IV, P32.5, PP4-X, Placental anticoagulant protein II, PAP-II, Protein II.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Zymogen granule membrane; Peripheral membrane protein.
Protein: ZMYM2_PONAB
Sequence: MDTSSVGGLELTDQTPVLLGSTAMATSLTNVGNSFSGPANPLVSRSNKFQNSSVEDDDDVVFIEPVQPPPPSVPVVADQRTITFTSSKNEELQGNDSKITPSSKELASQKGSVSETIVIDDEEDMETNQGQEKNSSNFIERRPPETKNRTNDVDFSTSSFSRSKVNAGMGNSGITTEPDSEIQIANVTTLETGVSSVNDGQLENTDGRDMNLMITHVTSLQNTNLGDVSNGLQSSNFGVNIQTYTPSLTSQTKTGVGPFNPGRMNVAGDVFQNGESATHHNPDSWISQSASFPRNQKQPGVDSLSPVASLPKQIFQPSAQQQPTKPVKVTCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHKPAPKKLCVMCKKDITTMKGTIVAQVDSSESFQEFCSTSCLSLYEDKQNPTKGALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRMANGLIMNCCEQCGEYLPSKGAGNNVLVIDGQQKRFCCQSCVSEYKQVGSHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCRFFDMTQCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQTTMPDGKLYNFCNSSCVAKFQALSMQSSPNGQFVAPSDIQLKCNYCKNSFCSKPEILEWENKVHQFCSKTCSDDYKKLHCIVTYCEYCQEEKTLHETVNFSGVKRPFCSEGCKLLYKQDFARRLGLRCVTCNYCSQLCKKGATKELDGVVRDFCSEDCCKKFQDWYYKAARCDCCKSQGTLKERVQWRGEMKHFCDQHCLLRFYCQQNEPNMTTQKGPENLHYDQGCQTSRTKMTGSAPPPSPTPNKEMKNKAVLCKPLTMTKATYCKPHMQTKSCQTDDTWKTEYVPVPIPVPVYIPVPMHMYSQNIPVPTTVPVPVPVPVFLPAPLDSSEKIPAAIEELKSKVSSDALDTELLTMTDMMSEDEGKTETTNINSVIIETDIIGSDLLKNSDPETQSSMPDVPYEPDLDIEIDFPRAAEELDMENEFLLPPVFGEEYEEQPRPRSKKKGAKRKAVSGYQSHDDSSDNSECSFPFKYTYGVNAWKHWVKTRQLDEDLLVLDELKSSKSVKLKEDLLSHTTAELNYGLAHFVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDPGYQTFEQELNKILRSWQPSILPDGSIFSRVEEDYLWRIKQLGSHSPVALLNTLFYFNTKYFGLKTVEQHLRLSFGTVFRHWKKNPLTMENKACLRYQVSSLCGTDNEDKITTGKRKHEDDEPVFEQIENTANPSRCPVKMFECYLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSTSLDRNTLENMLVRVLLVKDIYDKDNYELDEDTD
What is the function of this protein?
May function as a transcription factor.
What are the official names of this protein?
Zinc finger MYM-type protein 2, Zinc finger protein 198.
What are the subcellular locations of this protein?
Nucleus.
Protein: XGPT_KLEP3
Sequence: MSEKYVVTWDMLQIHARKLASRLLPVEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPIAGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NU6C_OENBI
Sequence: MDLPGPIHDFLLVFLGSGLIVGGLGVVLLTNPIFSAFSLGLVLVCISLFFSLSNSYFVAAAQLLIYVGAINVLILFAVMFMNGSEYSKDLTLWTVGDGITSLVCTSIFISLITTILDTSWYGIIWTTKSNQIIEQDLIGNSQQIGIHLSTDFFLPFELISIILLVSLIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL14_ACET2
Sequence: MIQVQTMLKVADNTGAKKVMCIKVLGGSKRKYANIGDVIVASVKDATPGGVVKKGDVVRCVIVRSKRGIRRPDGSYIRFDENAAVLIREDKNPRGTRIFGPVARELRDKEYMKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: YBEY_HAEIN
Sequence: MGSVLVDLQIATENIEGLPTEEQIVQWATGAVQPEGNEVEMTVRIVDEAESHELNLTYRGKDRPTNVLSFPFECPDEVELPLLGDLVICRQVVEREASEQEKPLMAHWAHMVVHGSLHLLGYDHIEDDEAEEMESLETQIMQGLGFDDPYLAEK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEMA_DROME
Sequence: MSKGGEHKRVTLTSIIQGDAGFSRFGSNILEPDAASAAPDNSSKPTTKTAKCIRIKLDLFETDSNKYPEFNYSRLLYLEKKKTKKLKQVSTTNGSASTDPFADNDDDVARIVKELEAKYGNSYATGRGKSKKDDYRDIGMGYDESDSFIDNTEAYDEIIPEEAETLEGGFYINCGALEFKNLTKKSYTTRTDAIIKMPERSRKRMVSSSSESSSSSSGDDDENDDGNNEEDDESDSEDDSEENDESDSEDDSESESLEDEDSAATAKSSSKYKDNHQAKRAKVIVTGKSKPSSSSLTSGKKPPTKPITTSSSSNSPRPSTVEISDTEDGQDPIQTQPSSQLQSLPQSQAQAQALKKVVKTTTVKDMLKAKRDSFLKSQSGTAAVKGVGNGELKCVSTDVSSSDSSDMESEHGRADRQAGQHGKDGQENLRTADTLLPTTLDADIVTAVNSFKEAVKSRDMCGKKFNLDVKLSPLLLRVYEAVLCTDRNERNMVFSHIEYQLQLPKYYMLRKGKQVRAKEEKRKSTIMLEKLRRAVAVVMPKAVANYETELRTFAEQAAADVNSELPPKMPRKKFQWTSELRHLLYDVYQARWTSYAFLAKRKESLEEFINWYLKEKVVELWPPGWMRLDELQREITRYKNAKLKAKEKPKAPPASASPKPVGVVSAPEQMPPASSYLKAVEDPRSRGNSDTDSATSASSNSLKRKLKEMPKQTSKPPKKKVAKQVPLQPQLTPHPQFQLAPAATAAVSIPAISNNNNHLPHLDTLLSMPSTSAQAAALNAAAVAAASTVLDLASPSRKIDLNTSNNFYNLITAASLAASGNPSPHSGDGQAKVIVGARPSPHVINLDDYQCTSDILQTSKQLAATTTVITAISKAAQTTSVARESSSESDGVEIVGVFPASKPQKKVQSKPKNKTQNRGRSSLGAVGQVNGSLGYSANNMYIYNSPRTLGPVYDLTDPHIMKTMSNLKEMEKQFIQAAFSPNSVKGASGGMGSSAPSTPTRQ
What is the function of this protein?
May play a key role in egg organization.  May be a transcriptional regulator having a role in chromatin remodeling in concert with Hira, a histone chaperone.  Involved in chromosome segregation by affecting kinetochores function in the first meiotic division.
What are the official names of this protein?
yemanuclein, Yemanuclein-alpha.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Chromosome. Chromosome, centromere, kinetochore. Note=Abundant in the nucleoplasm. Only a fraction of the protein is associated with the chromosomes. Localizes to the chromosome arms and coexpresses with cid at the centromere.
Protein: NU4LM_CAPHI
Sequence: MSLVYMNIMTAFAVSLTGLLMYRSHLMSSLLCLEGMMLSLFIMATLMILNSHFTLASMMPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: C525A_DICDI
Sequence: MDTTKNNDEFDISYFLTCSIFGFILWILTEQILKYYNKTNKNNKYNLPKGPSFLKWFINYLFNFYDLKLSNNKEEDNNNNNNKSNNSLSQEELIEDTSENTVLKWFNQLNSDNYSVSFFGRPMIFTRDTTISKYILSSNNIDNYTKPPDSSGVLIRLAQNSILMSEGDQWRYHRSIINQPFSSKNVKLMIPTIITTINKLINHLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTIIIDIHSYCTKLTFDIIGKLSIGYDFNSIESSDNDNDNNDDDDISKQFDFILNEMIRPIRRFSSYLPLYNDIKLFKFLNELESIIKGAINSRSLITDNNNNKTYKKNFLLDNLLDDNVKEKDIIGNINTFLLAGHETSANLLTFIFYLLSTHNNVQNDLYNHLIENQKKKINKDNKFTEEDEDYQSIEFLDWVIYETLRLFPPAPMIGRTSKNDDILKSGNNNNNNNNNISIPSETLILISVYAIHRDPKLWKDPNIFNPYRWKNIENINNRSDFIPFSSGGRVCVGQKFSIVEARIIISKLILNFELSFNNLKSKPFKIYQRATLTPKYPVFLNFKKRENK
What are the official names of this protein?
Probable cytochrome P450 525A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TIG_MESH2
Sequence: MIKREFLPESAELKIKLTADSKKWAEFYQKAEQKQAAKVSLRGFRKGKVPLEKARAYLNPQAVFELALRMFLPELEKQAATNIIDSDNVIESPIFNIVNMDKNNLEIEFLYPVYPEIKLPDYKNLKTKFAIKKITKEDIELQKQKLLEAKGRFIEVNRPVKIGDVINFNFKGFIDDEPFDGGEGENFDLRIGSNSFIAGFEEQLVGLEIKKEADIYVTFPENYQVHTYANKKARFRVKINKIKENQPAKLTNEFVASLKIQNVETISQLEVYLENLTERENIERAKIDFQKNALTEIGEQVEVPLAKKLINLEIERLNEVFHSTLKQQEIPLKEYLKITKFTEKDIYDQFEVEAKKLLKNSFIFAEIAKLEGLVPTQQEYESHVEKLAKFTGKSVQEISETVSYNEIQINITNQKVIDKLIEFNHETKDEEIVNKNQNDNEIEQDKEQKDNNEEKIKQENNLENK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.