PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_CLOP1
Sequence: MDKKKYIRNFSIVAHIDHGKSTLADRLLEKTGTLTQREMEQQVLDTMELEKERGITIKSQAARLIYKRENGEEYILNLIDTPGHVDFTYEVSRSLAACEGAILVVDATQGIQAQTLANCYLALDNDLEIVPVINKVDLASARPDEIKQEIEDVIGIEAEDAPLVSAKTGLNIEDVLEEIVEKVPAPEGDENAPLKALIFDSYYDSYKGVVCHIRVKDGKVKPGTKIKLMSTDKVYEVVETGVFTPALMPLKEGLSAGEVGYITASIKNVRDARVGDTVTEAARPTEEALPGYKPAIPMVYSGIYPVDGAKYEELKEALEKLQINDAALSFEPETSVALGFGFRCGFLGLLHMEIIQERVEREFNLDIITTAPSVIYKVTKTNGESFDLTNPTNLPPMTEIAYMEEPVVKASIITPTDYTGAVMELCQDRRGKFIDMQYLEETRVVIHYEIPLNEIVYDFFDTLKSKTRGYASLDYELKGYEQSKLVKLDILLNGDNVDALSMIVPEVKAYQRGRAIAEKLKEIIPRHMFEVPIQAAVGSKIIARETVKAMRKDVLAKCYGGDISRKKKLLEKQKEGKKRMRQLGTVEVPQEAFMSVLKVD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KDSA_FRATM
Sequence: MKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSSINSFRGLGVDKGLEILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQTPAFLCRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMVCERGVSFGYNNLVSDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMETHPNPDEAKSDGLNSFPMYKIKEFLSLLKELDHLVKSQPKTEL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_STAMF
Sequence: MVMLDTLANALATIQNAEMRAKSEALIWPASKLIINVLRVMQREGYIGEFEYIDDGRWGKIKVQLLGRINKTGVIKPRFPVKLRDLERMPHWLRKYLPAYNIGILILSTPHGVLSHKEAIAKKTGGVLLAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NEDD4_RAT
Sequence: MAADDTEAPVLSEDEVWEFCLDKNEEGGGSPGSDVTDTCEPPCGCWELNPSSLEEEHVLFTAESIISSFNNDDTRVVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGVLTSVQTKTIKKSLNPKWNEEILFRVLPQQHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPRSHKSRVKGYLRLKMTYLPKNGSDDENADQAEELEPGWVVLDQPDAATHLQHPPEPSPLPPGWEERQDVLGRTYYVNHESRTTQWKRPSPEDDLTDDENGDIQLQAHGAFTTRRQISEDVDGPDNHESPENWEIVREDENTIYSGQAVQSPPSGHPDVQVRLAEELDTRLTMYGNPATSQPVTSSNHSSRGGSSQTCIFEEQPTLPVLLPTSSGLPPGWEEKQDDRGRSYYVDHNSKTTTWSKPTMQDDPRSKIPAHLRGKTPVDSNDLGPLPPGWEERTHTDGRVFFINHNIKKTQWEDPRMQNVAITGPAEPYSRDYKRKYEFFRRKLKKQTDIPNKFEMKLRRANILEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATEDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPTELDLRFIIDEELFGQTHQHELKTGGSEVVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSLNHQVIHWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGFDGVD
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Specifically ubiquitinates 'Lys-63' in target proteins (By similarity).  Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes.  Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes.  Promotes ubiquitination of RAPGEF2.  Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity.  Is involved in ubiquitination of ERBB4 intracellular domain E4ICD (By similarity).  Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development (PubMed:20159449).  Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2 (By similarity).  Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (By similarity).  Ubiquitinates DAZAP2, leading to its proteasomal degradation (By similarity).  Ubiquitinates POLR2A (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase NEDD4, HECT-type E3 ubiquitin transferase NEDD4.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Recruited to the plasma membrane by GRB10. Once complexed with GRB10 and IGF1R, follows IGF1R internalization, remaining associated with early endosomes. Uncouples from IGF1R-containing endosomes before the sorting of the receptor to the lysosomal compartment (By similarity). May be recruited to exosomes by NDFIP1 (By similarity).
Protein: YTH1_CRYNB
Sequence: MAAASNSAPLDPKLGRAADFVRPDFHQVNLDLENYLKTERNFKLDADQQICPLSITPLGCPLPPSQCPYRHTTPSQLNFKPPPPLPAHPREREKKLTVCKHYLRNLCKMGDNCEYTHDFNLRTMPVCIWFVKQGKCELGGECLYFHPRDRRVECPDYNRGFCVLGPNCPRKHIRRRLCDAYAAGFCPDGKDCKLAHPSPNRPPAESYINPIPPDPEAFNGPPPQLPAGYGRWREYKYDPNAVVVPAAAWVEGGSLSGWRAGGFLSANARRDNQRNRDNDDEGGRGSGGERKGGWQKDLSTVLCFRCNQYGHFANNCPNQYVPGDRGGGRRRE
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
mRNA 3'-end-processing protein YTH1.
What is the protein family that this protein belongs to?
Belongs to the CPSF4/YTH1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL13_DINSH
Sequence: MKTFTAKPADIEKKWILIDAEGIVLGRLASIVATRLRGKHKATFTPHMDMGDNVIVINADKIQLTGNKRNKPNYWHTGYPGGIKSRTTGQILEGKFPERVVTQAVKRMLPGGPLSRQQMTNLRVYAGAEHPHEAQSPEVLDLASKNPKNTRS
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS12_SYNJB
Sequence: MPTIQQLIREERSVAARKTKSPALKACPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGTLDAAGVKDRKQGRSKYGAKRPKPGQAPAAAGKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: FOS_MSVFB
Sequence: MMFSGFNADYEASSFRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTVTATSTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTQSAGAYARAEMVKTVSGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDKKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEASTPESEEAFTLPLLNDPEPKPSLEPVKSISNVELKAEPFDDFLFPASSRPSGSETSRSVPNVDLSGSFYAADWEPLHSNSLGMGPMVTELEPLCTPVVTCTPLLRLPELTHAAGPVSSQRRQGSRHPDVPLPELVHYREEKHVFPQRFPST
What are the official names of this protein?
p55-v-Fos-transforming protein.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CUTC_SALA4
Sequence: MALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSFGVLRSVREHITIPVHPIIRPRGGDFYYTDGEFAAMLEDIRLVRELGFPGLVTGVLTVDGDVDMSRMEKIMAAAGPLAVTFHRAFDMCANPFNALKNLADAGVARVLTSGQKADAAQGLSIIMELIAQGDAPTIMAGAGVRANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGAAVAEMKGIIVRHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_LACGA
Sequence: MINVITGRQVDNLQNEIIDQAVKSYYQDKTHDVFIIVPNHIKFTTEVRALSKLSVLTNKKQVAVNKLHILSFSRLAWYFLKDEAIKLPQILDDAASVMLLEQIVKDHQDELKLFQNKNQITSGALRQMYEAILSVRAGNIDLENIDNEKLNEETSYKVHDLQIIYDDFIDRLSEKFATKDEMQLLLNEFLAKSDSLSTMVFYFSDFSHFSLQELTSVRLISKKAKNTTLAFKTKIGKIDSKAEQGDYDYVVQRTIRQLEHFWQNQQLNYQTTEFPLTKTNPSSLLNGVWTKTNGFDESLSKFLQPVKADSRYAEAYFVARTIYQQVALNNYRYQDFLVLAPNLNEYETYLTPILRQNNIPFFNDLQKEMKYHPLVVAVENLQQIFKRGFQTDNVIALMKTQLFIPEWYKSVARYQNDVDLLENFVLAHGIKGELWKKPLKSFVDAEVIALDKSEQEVEELDRLRKYFISILSEFFEDIETEKDPQAGVTIFWNFLIKNRVAKRLEAWRKEANDAGDLQLAQQPEQVWSTLNDLLKDYLLVAKEFSLEQFFDLLISGFSEANFSQIPSTLDAVNISEMGMVQGQGYKQVFIIGATSSNLPQIEKIPGFFSSENLEQLNDGNNASGYLEDQQKINNLDQNYQFGNALSLASDKIYISYPVINTANEQLEPSIFYKQLLRLTQANEFSQHDLPSSAGDLLTFMTNPEASLGYLTYLKGKQEVNVDSILELTEQEIGEVAQNVLEGSNFKNVPENLPPKLAQELYGDRIETSVSQLETYYQNSFEYFLNYGLHLKKRFENELDVIQAGNYYHETFDYLVKKIKEKNLDFADLTDSKLNQLLIEVREELKEKGRYRQLLNDPFNKYLFHKLDQTTSNVAHYWHSNVNKTTFRPQYSELSFGKNQKVTGLSYSWKDENNQKKIVDLRGKMDRVDLAKVNDRVLGEVIDYKSSAKKFDLGLFANGISMQMISYLEVLKKNNKFFAQGKNLDVLGAFYQNITSSLERLSSDKMILSNYQIKDLLKESTKKLMYNGILVADEEILDLIEPGMEKDRATSEIYSSIKRKVNGDISWPRNQSFTPDQLELLLAYNSYLIKNAGSEILSGKIKLDPYTYGQQSSLTYSDFKDIFFFDAMLKENNYHKIKAIDKKTLLNLIKEKLDLDGDE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: MGLA_MANSM
Sequence: MTAQSAQSDNQVLLTMTNVSKSFPGVKALDKANLTVKSHSVHALMGENGAGKSTLLKCLFGIYAKDEGEILFLGKPVNFKTSKEALENGISMVHQELNLVRQRNVMDNLWLGRYPLKGVFVDHTKMYNDTKAIFDELDIDIDPREKVANLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLSEKEVEHLFKIIEKLKDRGCGIVYISHKMDEIFKICDEITILRDGKWINTVPVKGSTMEQIVAMMVGRELTQRFPPKINEPKEVILEVEHLTALNQPSIQDINFELRKGEILGIAGLVGAKRTDIVETIFGVRERKSGTVKLHGKIMKNRTALEAINNGFALVTEERRSTGIYANLSIEFNSLISNMKSYMNKWGLLSDKKMKSDTQWVIDSMNVKTPSHKTTIGSLSGGNQQKVVIGRWLLTQPEILMLDEPTRGIDVGAKYEIYQLIMQLAQKDKGIIMISSEMPELLGITDRILVMSNGKVAGIVETAKTSQEEILQLAAKYL
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Galactose/methyl galactoside import ATP-binding protein MglA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SSB_BPB03
Sequence: MTNEIKATFDVTTLEGRMKILNAKNAGGASLKTCVDGTIIEAVGIAQYQQESDTYGDMKEETVTAIFTADGDVISAISKTVAEAATEIIDLVKEFNLDTFKVKVSKQKSSKGNEFFSLLLVG
What is the function of this protein?
Single-stranded DNA binding protein required for the elongation during viral DNA replication by strand displacement.  Displaced viral DNA strands are transiently coated with the ssDNA-binding protein and therefore protected againt nucleases.  The latter is then probably removed by the replisome that performs lagging strand synthesis or during the events that lead up to the recombination process.  Has helix-destabilizing activity since it removes secondary structure from the ssDNA in replicative intermediates.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB, Gene product 5, gp5, Protein p5.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus single-strand-binding protein family.
Protein: ADDA_STAHJ
Sequence: MNNIPIKPKDAQWTDAQWKSIYANGQDVLVAAAAGSGKTAVLVERIIQKIIRDEIDVDKLLVVTFTNLSAREMKHRVDQRIQQASIEDPRNEHLKNQRIKIHQAQISTLHSFCLKIIQQHYDVIDLDPNFRTISDVENVLLLEQSIDEVLEKHYDTPDIEFLTLVEQLSSDRNDDNFRDLLKRFYNFSIANPSPFEWLDSLVEIYTDDNKHKLYLDELERLSKIYIKAAYHTLLEAENNFLNCIEAEKHLDVIKLEKFKCEKMIEGNVINFEEIINYTSEKLPTITKKLKDTNEDEGISSQFLTNAKDFFDDYKKLLSEVKNKYLMRSYEDLKVDMKRLAPRIQYLVQIVKDIINGFAEKKRSRNVLDFSDYEHFALQILTDQEGNASPIAKEYRSQFEEILVDEYQDTNQVQEAIISKIKRGDESNGNLFMVGDVKQSIYKFRQADPTLFMDKYHRFTKDGDQSGLRIDLSKNFRSRKEVLATTNYLFDHMMDEEVGEIEYDADARLYFGATKYSDKSMPLELHALIQDKSSDNDLEKSEQEARYIAEQVKYIIEHKQVYDMKSETYRQATFKDIVILERGLKNARNLQQVFKDYNIPFHVNSKEGYFEQTEVRLVLSFLRTVDNPLQDIYLVGLMRSVIYQFTEDELANIRVQSMNDDYFYQSILHYMKDQEANPLLVEKLEHFMDDINMYQEYSQSHPVYQLIDKFYNDHYVIQYFSGLIGGKGRRANLYGLFNKAVEFENSSFRGLYQFIRFIDELIERNKDFGEENVIGPNDNVVRMMTVHSSKGLEFPYVIYSELSKNFNKGDLRKPLILNQKYGLGIDYFDLEQNVTYPSLSSVVIKSITEKELISEEMRLMYVALTRAKEQLILIGTIDKEEALEKLERLPISGNQIALHKRLSADRPFDLIYSILAKYQSTSLLPEYRFEKSIDNLDESLRPTVDIKIAQFEELSIEDSESEQESRNISDLEVEGSHDDTLKQQINDQLSFKYPYLKDTEKPSKQSVSELKRQLETEESGTSYERVRQYRIGVSTYERPKFLRENKKRKANEIGTLMHTVMQHLPFKETRMTETELNDYINELIEKHIIEEDAKKDIQFEAVMNFIRSDLYMTITQADKVYRELPFVVNQARVDEMPESDEDVSIIQGMIDLIFLKDDQYYFVDYKTDAFNKRRGMTDEEVGIQLRDKYKIQMKYYKNTLETILNSKVYGYLYFFQFGQMSIEEDV
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: FABH_PSET1
Sequence: MPYAHITGWGKCIPPASISNDEISKIVDTTDEWITSRTGIKSRRVSHVSTAELATVAAKHAIACAGIDAKDIDLVILATCTPSTMVANTASLVQKNIGAVGAAAMDTNAACSGFLYALQAATAQIQAGMIKKAVVIAAERMTWYVNWSRRDSAVLFGDGAGAVVLEAADTPAGLLATKTGCDSTDRDILHIENFGSDLNKYEPIGPSNLLFEGREIFKRAVKGMSEACDDVLAQANLSLDDINVLVPHQANLRIIQAIQHRLKVPDEKVMVNIGQYGNTSAATIAIALCEAVEQGLIKPHSNIMSAAFGAGLTWAASYIKWGERVTPISVSDAQLPPCDKTGLELVAPAVKACKEAEPT
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_PROM5
Sequence: MTSSIECQNIFRSLQLLDLFIKIGVKNLILCPGSRSAPLAIAAGELYKYGILNVFNSIDERSAGFHSLGISTASGDISLVVTTSGSAVGNLLPAAVEADRSCKSIVFITADRPLRLKNCGSNQTVNQEAFLNSVCRSTLSTNLNGIHKNNDDDILKIVKMIKKQLLQSPGPIHLNIPFEKPLDISLKNKRKTLKVFETLYLNKTCKFLKQNEQNKSIHFSKRIFESLDLSNSGIIIVGPYQGSIKDLVSFNNSLEKIQSITGWPVFADPVSGVSADLRGLVENWELIIKKNNNVIKCNQILRLGPLSSSNNLEKFLSDFDGIQILVKENNRRKLDPIKKSLEYEFGLTNFVNQLLGTYSDDQKKKKPLINLVKVLRREGQKISKILNEQIFLNKEITEYKLANFVPKIWPENYPIMLSASSPIRDWLTFSENGTLTRKCFSFRGASGIDGTLSLALGIARITQPLLLVTGDLALIHDINGFLIENSIDLNLTVLLINNNGGNIFNNLYKNNLEKEELKKLFLMPKSINWENLAKAFQVPIKIVSDLNKLPESFEWSLSMQKSVIIKVDINVDNEMKERSLILKKILNN
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: DNLJ_STRPC
Sequence: MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQSYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNATYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTITVRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQEASPTARNQQNEVLAELAGLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVVIKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIPKLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFLAGFVHDVADIYQLTKENFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGSKVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAGVNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVIAGSDAGSKLEKAKSLGIRIEDEDWLRQL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RF3_XANAC
Sequence: MSEVSNEAARRRTFAIISHPDAGKTTLTEKLLLFGGAIQMAGSVKGRKAARHATSDWMALEKERGISVTSSVMQFPYEGKIVNLLDTPGHADFGEDTYRVLTAVDSALMVIDVAKGVEERTIKLMEVCRLRDTPIMTFINKLDREGKNPIDLLDEVETVLGIQCAPVTWPIGMGQRLKGVVHLISGEVHLYEQGRNFTRQDSTIFPSLDAPGLVEKIGEQMLAELREELELVQGASNPFDLDAYRAGQQTPVFFGSGVNNFGVQPLLDFFVEHAPPPQTRETTGRRVEPTEAKLSGFVFKIQANMDPQHRDRVAFMRVCSGKFTAGMKTLHVRSGKDVKLANALTFMASDREIAAEAWPGDVIGIHNHGTISIGDTFTEGESLSFTGIPNFAPELFRRARLRDPLKLKQLQKGLAQLSEEGATQFFRPLMSNDLILGAVGVLQFDVVAYRLKDEYGVDAIFEPVSVTTARWVHCDNPKKLEEFREKNAGNLGIDAAGELVYLAPTRVNLQLAQERAPDVRFSATREHAHVKAVD
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_MYCCT
Sequence: MKSNYDVIVVGGGHAGVEAALASARLNKKTALINLYEDKIATMPCNPSVGGPAKGIVVREIDALGGEMAKAADATALQTKLLNSSRGPGVWALRVQSDKEEYSKYMRNVIKKQKNLDLITKACTGLVYDDNKSVTGIYLDDEIILNAKAVIITTGTYLKSEILKGIDRYESGPNNEKTTKGISKSLIDLGIKLMRFKTGTPARVYRDSVDLSRAIIEPGTDMKLAFSFSTNTYTPIEKQQPCYLIHSTLETKKIIEDNLEKSAMYSGTVESIGPRYCPSFEDKVVRFKEKDTHQIFIEPETLNGDTWYVQGFSTSMPIEVQELMLKSLPGFENVRVKHWAYAIEYDCIDPMQLSPSLELKDVRNLFTAGQINGTSGYEEAAGQGLIAGINASRKIDGLDPIILRRDEAYIGVMIDDLINKGVWEPYRLLTSRAEHRLLLRNDNAETRLKQYGREIGLISDTEWEQYLIYVKEIEQAIKELKEIRFTPKSQLAINLKNKKQADLSHGYSGYEIIKIPTVDINELIEFIPSLQKLKTNQLQSIVIEIRFEGYVKKERQLVDKLVKLERKKIPLDINYSKVDNLATEAKDKLEKIRPLNIGQASRITGVNPADIQMLLFYLKKQYPLESIDD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PETMO
Sequence: MPLKIEDLKPTPGSRKPKKRLGRGIGSGLGKTAGKGHKGEKARGRGKIGRTFEGGQTNIIRRTPKFGFSNAPFKKVYSVVNVETLEKYFSENEEVTPDILLEKKLIKKLNDGVKILGKGEISKPLVVKANIFSQTAREKIEAVGGKIEVIE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: GLMU_LACPL
Sequence: MTTKNAIIMAAGKGTRMKSKLVKVLHQVCGKSMVDHVLTQVEATHMANIVTIVGHGAKDVEAALGDRTEYAVQTEQLGTGHAVLQAESLLKDADGMTLIVSGDTPLFKAETFEELFEYHQAKGAAGTILTSKAPNPQGYGRVVRNRLGIVEKIVEQKDATKEEQEIHEINTGVYCFDNQKLFAALHEVTNDNAQGEYYLTDVIQIMKNQGDVVAAYQMDDFDESMGVNTRAALAQATKVMQQRINAQHMENGVSIINPDDTYIDAGVKIGADTIIEPGVLIKGHTTIGEDCFIGAHSEIHDMVIEDRVRVTASFLEDSIMHADSNIGPYSHLRPQAEIGEHVHLGNFVEVKKAKIGNRTKVGHLTYVGDATLGQDINVGCGVVFVNYDGVNKHHTNVGDSAFIGSNSNIIAPVEVADHSFIAAGSTITDDVNFHDMAIARARQTNKPDFWGRLPHEPENM
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCCT_SALEP
Sequence: MKTGALATFLALCLPVTVFATTLRLSNEVDLLVLDGKKVSSSLLRGAESIELENGPHQLVFRVEKTIRLPGNEERLYISPPLVISFDTQLISQVNFQLPRLENEREASHFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASLPQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQPPS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: COAD_AZOSB
Sequence: MRDGVAIYPGTFDPFTRGHEDLVRRASLLFDQVVVGVAESRGKAPIFTLEERVEIAREVVKPFPNVRVAGFDGLLMDFLRAQNGRVILRGLRAVSDFEYEFQMAGMNRKLFPDVETVFLTPAEEYMFISATMVREIARLGGDVSKFVQPSVLTQLQQKVSSKR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_BURA4
Sequence: MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLHPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRADKPQGPRPSSRYPRVIGTQSQQTLTIVDTSVVCSEIEVEASTLDEMPPRVIVGK
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.