PharMolix/UniProtQA huggingface dataset:
Protein: TONB_MANHA
Sequence: MKKKHSRIGLLASLAIHTALIGGTFAWLHNHKVKKLPSKTLFLWKWWQALLDEPQVAVAPDPITEEVKEIEPEKAEVPPEPKLTPEPTPEPDEFQILRLNPKKEKPKEEKRKERHHHKHKHRHKEKREELQEQEKPKDKPKERPKHHHKHIKALDAGPEIKQGIVAKAIPNAAEGEKVVAGVVGGQKNGSPNSTSTTGSANTGASSGNASELPAYKVALQRALQRKANNSYPQREKMNAENRYSYD
What is the function of this protein?
Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates.  It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
What are the official names of this protein?
Protein TonB.
What is the protein family that this protein belongs to?
Belongs to the TonB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: CH10_AROAE
Sequence: MKIRPLHDRVIVKRLEAERKTASGIVIPDSAGEKPDQGEVLAVGNGKILDDGKVRPMAVKVGDKVLFGKYAGQTVKVEGDELLVMREEDIMGVVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_SALPC
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEYTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGGVPGATGCDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DGTL1_MYCSS
Sequence: MNPRLQDSYDEFDRQRRVDEPAKSAVLPGTGTEHRTDFARDRARVLHCAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAVGLGCDPDLVDLAGLAHDIGHPPYGHNGERALNEIAKAFGGFEGNAQNFRILTRLEPKVLDATGRSAGLNLTRAALDAVTKYPWQRGDRTKFGFYGDDMAAAWWVRDGAPAERPCLEAQVMDWADDVAYSVHDVEDGVVSGRIDLRVLADDDAAASLARLGAEAFPTLAPDDLLAAAERLSQMPVVSQVGKYDGTLGASVALKRMTSELVGRFANAAITETRSVAGGGALHRFVTELAVPTLVRAEVAVLKMLALQFIMSDHGHLGIQADQRTRIHEVALILWGQAPSSLDPLFAPEFVAAEDDGARLRVVIDQIASYTEGRLERVHEARSPRPLD
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: SYGB_ECOUT
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDKLEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y606_BACC1
Sequence: MGEENQPNYTISQENWSLHRKGYDDQQRHQEKVQEAIKNNLPDLVTEESIVMSNGKDVVKIPIRSLDEYKIRYNYDKNKHVGQGNGDSKVGDVVARDGSGGQKQKGPGKGQGAGDAAGEDYYEAEVSILELEQAFFKELELPNLKRKEMDENRIEHVEFNDIRKTGLWGNIDKKRTMISAYKRNAMRGKASFHPIHQEDLKFRTWNEVLKPDSKAVVLAMMDTSGSMGIWEKYMARSFFFWMTRFLRTKYETVDIEFIAHHTEAKVVPEEEFFSKGESGGTICSSVYKKALELIDNKYSPDRYNIYPFHFSDGDNLTSDNARCVKLVEELMKKCNMFGYGEVNQYNRHSTLMSAYKNIKDENFRYYILKQKADVFHAMKSFFREESGEKMA
What are the official names of this protein?
UPF0229 protein BCE_0606.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: MRAY_PARMW
Sequence: MTDISNRPRTWWENGTVSASLLAVAVLAGSLASDKWVPNSQLTLPLLISTSVAALVAAAGIPRLKALKMGQVIRVEGPQAHQSKAGTPTMGGLLVVPVGTIVGGLISLEGTEAQQLLAVSAITLGYMVIGGFDDWRSLTRQTNTGLTPRGKLLLQSLMGVLFLAVAAWQGWISSSVSLPFGWTLPLGWLIWPLGLFVFLAESNATNLTDGLDGLASGCGALVFLGMAVQLMLRGHTGDPALAGFCMTMAGAWLGFLMHNRHPARAFMGDTGSLAMGAALSGVALLSDSLWPLLVMGGVFLAESLSVIIQVWVFKTTKGPDGQGRRVFRMAPLHHHFELGGTSERTVVPCFWLATAGFVLLGLLLRPTI
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYAY_RICFE
Sequence: MNNTEFSKIAETTIAYIADKIEEQDKEASIDVDLQGDILNLDTDKGIYVINKQSAAKEIWLSSPVSGPYHFFYEQGKWKNKIGLELMAILTEELNIKFDNI
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: PDRP_LACP3
Sequence: MTQELNLYIMSDSVGETGLRLAQAVAAQFPNFEAHYVRFPFIHTEEKIYSALDEAKKENALAIMTFVTSGFAQLATHYAKDQGVIAIDVMSPILSGIKSITHEEPNHVPGAVHDLNERYFDRISAMEFAVLYDDGKDPKGFLEADIVLLGVSRTSKTPLSLFLANRNLKVANLPLVPNAHIPEEIWSVDPKKIVGLTTDASVLMEFRRQRMIAYGLNPDTAYSARDQVNQELKFAEDLYKKIGCMVINTAHRSIEETATLILEHMGLDEFDNTETH
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RECR_RUEPO
Sequence: MAGSTKDIDALIELMARLPGLGPRSARRAVLHLIRKRALLLTPLADLMGQVAATARECLNCGNVGTSDICDICTDERRATGELCVVEDVADLWAMERSGVFKGRYHVLGGTLSALDGVGPDELRIPRLADRVTAEAISEVILALNATIDGQTTAHYIADQLGGRVRLTSLAQGVPIGGELDYLDDGTISAAMRARKEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: AKR1_SCHPO
Sequence: MGSLFLAASQGELDTVKNLISSEKIDVNATDEGGATALHWAALNQQIPICKFLLEHGADVNAIGGDLQAAPIHWAAKRGSVKTVHYLVQHGADPLLKDKQGFNCLHLAVHAASPLLVVYLLHLDISVDLRDDQQHTPLMWASYHGNEPITNCLLRWGADVLATDEDKMTPLHWSIVGGNLKCMKLILKEGGIPCTAVTANLSGQLKTPWALASELRVSHLFKQALISNGLKVKETSEEPEKWVVVPSKFQFSQKTFIIFCFLSSFIITGVFFFIMSICPMVISLIIAPLWIYFTFKYITTCIHANIDIVHFYLETPFLAGIFSSIFFWVWCHSLLYIVPKTLPIKPLSSLLFVLISFTCIGLYVRTAFQNPGYVDKIGAVVQRREEISKLLDKDLFNQSHYCLKCFQVKPPRSYHCGACKRCINRYDHHCPWTGNCVGARNHRTFLLFVFTLSTLIPIYFYVAFYYLQNIPIQKKYESYRCLFISGTICQWSLKDMFVLVASLTLFVNWCWVVVLAFTQICQVAHNVTTAEFRLFKRYGTLVPPTKQNSSPKNGHGIHGSFLRTVCGILGLDQCILLIRESNCFVRCFPSRAELGSQNSTSLSRNLSTVNPYDEGSIIKNCKTFWKQNFLNDGRQDEATRHV
What is the function of this protein?
Palmitoyltransferase specific for casein kinase 1.
What are the official names of this protein?
Palmitoyltransferase akr1, Ankyrin repeat-containing protein akr1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: Y31E_CAEEL
Sequence: MGNVATRKRPGCHHHIGRNEENLDDDEDGPAKKRLRIGEPQAENEYQKLAFKSRLQKLKKCRPHLKRRTYKVEEADPRPPVPRFIVDDYGDYEKPEPTRKEFAIPWFEHLFLPEFPTRSVINEKSFVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKKLKQGSSTGTICGTLQYMSPDVASGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATHHANLKFIDYSTPIGCSREFANLMDRMLAVSITHRLCSFTVLHAHPFFRSIDFSKLEQKDYTPAAEIGNAEYDTYHKSEDALDDALFKENYDVSCGRNVIFAVLPVFW
What are the official names of this protein?
Putative serine/threonine-protein kinase F31E3.2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: YDDC_BACSU
Sequence: MDFMNFFILGADLPTLGGVKGWASDVVIQFITIVVMFIAAKNLMKLKMGGIIFVCCIGSAVTWVIKHWSEFSGWINALMEKL
What are the official names of this protein?
Uncharacterized protein YddC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VPS41_SCHPO
Sequence: MSVDESNSDSEIDSISSSDEDEEPKLIYERITEKFQGCFMNDTISACAISKEHFFFGSHNGAIYIYQKNGILLRKMILHSASVVDLSVDLESENLASCSMDGKMIISNITTRETTVHDFKRPLLSVAIDPYYSTRSSRQVLSGGRAGKVVLSEKGWLGNKDTVLQADCGAVYKISWYTTYIAWASDLGITVYSTEFGKVLGRLEPPKRLPNDEIFPYQLFWQSESRLVIGWSDQIMIVSIQRSNVANELPKISLQALLEIDSIVSGVLMLGFNILTLAYIANVEDFTSAIPSQRIEGCRPELRLIDSSFKELCGDAIGLANYSRLQPSDYHLLPDPSSNSHSFVISPNDIVYVRERNQIDHVKYLVSKEMYAEAIDAVKKLPEIPPSLQISELAKKYIFHLLGKGQYKEAGMVIPSLYNDNLAEWEQWVFVFAENDHLEDIADFLPTGENHLSPLVYEMILAQYLATDERTFNKKLHEWPTMLYSVSTIRNATLKKFKENQKSSTLTESLAFLYLEDNMPIDAFHLYLKLHSELCIDLILQHNLYDEARASVLLLMLISSKGKSSDTKSAMSSMLVQHVHSFPPQEVIMQIHSVPQFLYEYFCEFELMYPNSLMEYGDLKLDVFAEFDRKRFFDFLVNTQCYSLDHAAQICKQYNYLDELVYILGRMGNNKEALMLIINELLDIGRAIRYVKEQADRELWDDLISYSLDKPEFICTLLENIGTDENARNLLSKIPPGTKLPHMKKSISKLLADHQSQVQLYQSCYKLFKNESISMAIKYREQEQSGLEFLVKDNPFNSFGDEQLDYNYRKRIPMIYDLRTKKYIRPEDVRIDTDDVFKDDKIAYFKTRMHLKPEVQMRNKLDLLMMLYKQT
What is the function of this protein?
Required for vacuolar assembly and vacuolar traffic.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 41.
What is the protein family that this protein belongs to?
Belongs to the VPS41 family.
Protein: F16PC_STAAM
Sequence: MTQITEKELKKKYLDLLSQNFDTPEKLATEIINLESILELPKGTEHFVSDLHGEYEAFQHVLRNGSGNVRAKINDIFKERLSTKELNDLTALVYYPEDKLKLIKSDFQSCGQLNVWYITTIEHLIELIKYCSSKYTRSKLRKALPKQYVYIIEELLYKSNEYQNKKSYYETLVNQVIELKQADDLIIGLAYSVQRLVVDHLHVVGDIYDRGPQPDKIMDTLINYHSLDIQWGNHDVLWVGAYAGSKVCLANLLRICARYDNLDIIEDAYGINLRPLLTLAEKYYDADNPAFKPKKRPDKHERLTQREESQITKIHQAIAMIQFKLEIPIIKRRPNFEMEERLVLEKVNYDTNEITVYGNTYPLKDTCFQTINRNNPAELLPEEEEVMNKLLLSFQQSEKLRRHMSFLMRKGSLYLPYNGNLLIHGCIPVDENGEMESFEIDGHTYSGQELLDVFEYHVRKSFDEKENTDDLSTDLVWYLWTGKYSSLFGKRAMTTFERYFIADKASHKEEKNPYYHLREDVNMVRKMLSDFGLNPDEGRIINGHTPVKEINGEDPIKADGKMLVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHQQFNAKEKILSEGIDELSIKRVVDKELQRKKIRDTNIGKELQAQIDILKMLMHDRYLD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: UVRC_BACC7
Sequence: MHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVGEIVDFEYIVTSSNLEALILELNLIKKHDPKYNIQLKDDKTYPFIKITAEKQPRLLITRNVKKDKGKYFGPYPNAQSAHETKKLLDRMYPLRKCSNMPDKVCLYYHMGQCLAPCVKEVTEEQNKEIVDEIIKFLNGGHKEVRSELETKMYEASEKLEFERAKELRDQIAHIDAIMEKQKMIMSDLVDRDVFGYAVDKGWMCVQVFFVRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYENSSHFKPKEIVVPGSIDSELVERFLEVEATQPKRGKKKDLVELANKNAKIALEEKFYLIERDEERTIKAVENLGKQLGIETPYRIEAFDNSNIQGTNPVSAMIAFIDGKPAKKEYRKYKIKTVQGPDDYESMREVVRRRYTRALKEGLPLPDLIIIDGGKGHLAAASDVLENELGLYIPMAGLVKDDKHKTSHLIIGDPPEPVMLERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSALDDIPGIGDKRKKILLKHFGSLKKMKEASVTEFVEAGMPKNVAETIYSYLADKKTL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C25_HUMAN
Sequence: MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAIVVKKVLEEVDQRSKILTTRLHSLEEKSQSN
What is the function of this protein?
Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity).  Plays a role in the cytoskeleton organization (PubMed:26902920).
What are the official names of this protein?
Keratin, type I cytoskeletal 25, Cytokeratin-25, CK-25, Keratin-25, K25, Keratin-25A, K25A, Type I inner root sheath-specific keratin-K25irs1.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_PROMP
Sequence: MKWIIQEEKEEDHLQILNKDSEIGIDEVGRGSVFGPVFSVAVVLSKKSGLTLKKLGVNDSKKLTPKKRKDFFPKIIALSSDYALGQSSVREIDLLGIRHATELSMIRAVKKLKHMPSELLIDGPLTLRLWEGNQRNIISGDSKFISIATASIIAKVMRDSLMERLESKYPGYFIFKNKGYGTKQHFSSLKKHGLTNLHRKSFLNKLNLI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSK2B_PIG
Sequence: MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
What is the function of this protein?
Regulatory subunit of casein kinase II/CK2.  As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).  Participates in Wnt signaling.
What are the official names of this protein?
Casein kinase II subunit beta, CK II beta, Phosvitin.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: HIS82_NITMU
Sequence: MNICDLAPAYIRAISPYQPGKPISELAREMGMDEQSIIKLASNENPLGTSPMALNAMSKALDEVSLYPDGSGFELKAALSERYGVTSDQIVLGNGSNDVLELAARVFLKPGASTVYSQHAFAVYPLVTKAVGGIGISVPARNYGHDLDAMLDAVAPETRVVFIANPNNPTGTLLPADDVLRFLERVSPDVLVVLDEAYNEYLPPALKGDSIAWLKQFPNLLITRTFSKAYGMAGVRVGFGLGHPDVAGLMNRVRQPFNVNNIGLAGAVAALQDEEFVKRSYALNQAGMLQIVTGLRQMGIEYIPSYGNFLSFRVPGNVKAINESLLKQGVIVRPISIYEMPEHLRVTVGLESENEKFLKSLAIALETTEGAAADTIPEMAVSFPKVASGGTA
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: UBIA_POLNA
Sequence: MTAGAPSKFSLYLQLIRWNRPAGWLLLLWPTLSALWLASHGFPGWHLVTVFTLGTFLMRSAGCCINDVADRDFDRHVKRTAQRPVTSGAVSVREALGLGAVLALLAFGLVLTTNAVTIAWSFAALAVTLAYPFAKRYVSMPQAVLGVAFSCGILMAFAAVQSRVPPLAWALLLGNLFWVIAYDTEYAMVDRDDDLKIGMKTSAITLGRFDVAGVMLSYLIFISIWAFALIQRAQSAIFMIAIALALAQALWHGWLIRKRERDDCFKAFRLNHWLGFTVFAGVALSYWGR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NKX24_HUMAN
Sequence: MSLSPKHTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSPSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox protein Nkx-2.4, Homeobox protein NK-2 homolog D.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPK2_ORYSJ
Sequence: MLGRAIRSMEVMVHSSTFLLPKLHQPANSPAKKYALVVLNQNLPRFVPRLWTHAKLRICADGGANRIFDEMFQMTNDPDYESTRKRYIPEIIEGDMDSIRPEVKQFYSSQGSKISDKSHNQETTDLHKCISRIHRCTPDHEKTNLCVLVTGALGGRFDHEAANINILYLFSDMRIVLLSDDCLIRLLPKTHKHEIYIESSVEGPHCGLFPVGAPSGSTTTTGLKWNLSEAKMRFGSMISTSNIVHAEKVTVQSDADLLWTISLRNLT
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP).  TPP is an active cofactor for enzymes involved in glycolysis and energy production.  Plant leaves require high levels of TPP for photosynthesis and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Thiamine pyrophosphokinase 2, OsTPK2, Thiamine kinase 2.
What is the protein family that this protein belongs to?
Belongs to the thiamine pyrophosphokinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MEPA_SALDC
Sequence: MKKTAIALLAWFVSSASLAATPWQKITHPVPGAAQSIGSFANGCIIGADTLPVQSDNYQVMRTDQRRYFGHPDLVMFIQRLSHQAQQRGLGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWSQAQLLRPQALDLVSRDGKHVVPSRWSSDIASLIKLAAQDNDVTRIFVNPAIKQQLCLDAGNDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVL
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FIS_SHEB5
Sequence: MFDQTTNTEVHQLTVGKIETANGTIKPQLLRDAVKRAVTNFFAQLDGQEAQEVYEMVLSEVEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: NCAP_I77AH
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRVDGKWMRELVLYDKEEIRRIWRQANNGDDATRGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGIGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVASGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFDKSTIMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RSXB_SALTI
Sequence: MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAILPQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKMAELLNVEPQPCDGEEQQAAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCIELRPVNETPDSWKWDLNTIPVRIIPVEQHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: GPDA_AZOC5
Sequence: MSAFDRIGVVGAGAWGTALANVAARAGRAVKLWSRDPAQVAEMAARRENARGLPGIALEAGVTPTADLREAAACEAVLLVVPAQVCRAVSGELAPLLAAGTPLVSCAKGIERGTAAFMTDVIRAAAPAARPMVLSGPSFADDVARGLPTAVTLAGEDGALAETLAAALGSSTFRLYHSSDVRGVEIGGAAKNVLAIAAGIVAGRRLGASAGAALTARGFAELQRFGRAFGAQPDTLTGLSGLGDLILTAGGPQSRNFAFGLALGQTGEVPQGGKLAEGAFTASALVAMAAGRGVEMPICAAVDAVLSGRLSVDGAIEALMARPQRAEA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.