PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_METTM
Sequence: MILNIRLDHKTSDVKTMETASGRIEEIVGELEALGAVTEKVPLMTCNRVEYYLHVTGVPPEFDFNGFTVEKDEDALLHLLRLASGLESMIIGEDQILGQIKAARLQALREGTCGPLLDMVFTKAVHVGQTVRRKTKINRGSVSIGSAAVDLAESIHGDLKCKKVLVIGAGKMGTLVARALAEKHLKAIMVANRTYERAYQLACELGGDAIHFDRLNRALRDADVVISATGSPHYILTRERVMDAVPPERRSSIVMVDIANPRDIEESVRELGVRLFTIDDLRGVAEENRKRREAEAREAEGIVRAELELLLRAMKHREVEPLLAEIRGRMESLRQREAGKAIKKIENSKDPERVVEGLTRSIVDKIFHDIALKIRDAAERDDREFLRMCSELFDCDES
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: BTUC_YERPG
Sequence: MQTSQLFTALQQRQRQRDYRYLTGLVVMLLFALLISLCAGDVWIWPEHWFSESGKLFVWQLRLPRSMAVIMVGASLAVSGAVMQALFENPLAEPGLLGVANGAGVALVTAVLLGHGLLPIWVLSTCAIIGALLMTSILLSFTRRRLLTNAQLLLVGVALGIICSAMMTWAVYFSTSLDLRQLMYWMMGGFSGVDWRQQSLVLALLPTVIWLCCQGRVLNFMSLGEQQARQLGVSLHLWRNLLVLAIGLLVGISVALAGVISFIGLVIPHILRLTGLTDQRRLLAGCAFAGGGVLLLADVVARTVLSSAELPIGVVTATLGSPLFIWLLIRVKGVK
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_CORGL
Sequence: MTVAPRIGTATRTTSESDITVEINLDGTGKVDIDTGLPFFDHMLTAFGVHGSFDLKVHAKGDIEIDAHHTVEDTAIVLGQALLDAIGDKKGIRRFASCQLPMDEALVESVVDISGRPYFVISGEPDHMITSVIGGHYATVINEHFFETLALNSRITLHVICHYGRDPHHITEAEYKAVARALRGAVEMDPRQTGIPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCN1_PANTR
Sequence: MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVSGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD
What is the function of this protein?
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion.  Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity).  CCN1-mediated gene regulation is dependent on heparin-binding (By similarity).  Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity).  Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 (By similarity).
What are the official names of this protein?
CCN family member 1, Cellular communication network factor 1, Cysteine-rich angiogenic inducer 61, Protein CYR61.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted.
Protein: YURZ_BACSU
Sequence: MEGFSLNQDRGSMQDALKQYKHGLGTFEQKMPLMGRKFNEFTEQCFAGNSLTEREKQLIALGIAINAQDEYCMIYHTKGCLDQGASEENILEAVSVAAAFGGGAAFSQGVTVVQQCIEEFGNTTH
What are the official names of this protein?
Uncharacterized protein YurZ.
Protein: NPM3_HUMAN
Sequence: MAAGTAAALAFLSQESRTRAGGVGGLRVPAPVTMDSFFFGCELSGHTRSFTFKVEEEDDAEHVLALTMLCLTEGAKDECNVVEVVARNHDHQEIAVPVANLKLSCQPMLSLDDFQLQPPVTFRLKSGSGPVRITGRHQIVTMSNDVSEEESEEEEEDSDEEEVELCPILPAKKQGGRP
What is the function of this protein?
Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning (PubMed:22362753, PubMed:20073534).  Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM (PubMed:22362753).  Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM (PubMed:15596447).
What are the official names of this protein?
Nucleoplasmin-3.
What is the protein family that this protein belongs to?
Belongs to the nucleoplasmin family.
Protein: RS12_ALKCK
Sequence: MPTINQLIRKGRVDKVKKSDSPALNKGYNSFKKSQTDVSSPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNQIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVQNRMQGRSKYGTKKPKDKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: IDI2_STAAB
Sequence: MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVNDIDLTSQTPDLTMAYPVYINAMTGGSEWTKNINEKLAVVARETGLAMAVGSTHAALRNPRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPEGNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNFVDIENERRANKDMDYLSSWGQSTVESLLETTAYQSKISVFASGGLRTPLDAIKSLALGAKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPEILSWIEQRNLNIHRG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_ECO81
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_PASMU
Sequence: MPLNLRHRHFLRLMDFTPTEIQFLLDLSANLKKAKYTGTEQPRLKGKNIALIFEKTSTRTRCSFEVAAYDQGANVTYIGPSGSQIGHKESMKDTARVLGRMYDGIQYRGYGQELVEILAQYSGVPVWNGLTDDFHPTQILADFLTMLEHGEGKRLNQMKMAYLGDARNNMGNSFVEGAALMGMDLRLVAPKAYWPEQKLLDEVAEMAKKTGAKITCTENVEEGVKGVDFLYTDIWVSMGEPEEAWEQRINLMKPYQVNKALLEKTGNPKVKFMHCLPAFHDENTTVGKEMAQKYGMNGLEVTDEVFESDASIVFDEAENRMHTIKAVMVATLGQ
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_ECOK1
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRINLQSGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RL32_SYNWW
Sequence: MGVPQRRQSHARKNKRRSEWRKIDKPGLVECPQCHELKMPHRACLNCGYYKSNKVM
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ACCO_PERAE
Sequence: MDSFPVINMEKLEGQERAATMKLINDACENWGFFELVNHSIPVELMDEVERLTKEHYKKCMEQRFKELMASKVEGAVVDANDMDWESTFFIRHLPVSNLSEIPDLTDEHRKVMKEFAEKLEKLAEQVLDLLCENLGLEKGYLKMAFAGTTTGLPTFGTKVSNYPPCPRPELFKGLRAHTDAGGLILLFQDDRVAGLQLLKDGEWVDVPPMNHSIVINLGDQVEVITNGKYKSVMHRVVAQTDGNRMSLASFYNPGSDAVIFPAPALVEKEAEEKKEVYPKFVFEDYMNLYAGLKFQAKEPRFEVMKMKAVETANLSPITT
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase, ACC oxidase, Ethylene-forming enzyme, EFE, Ripening-related protein PAVOE3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: HSCB_ACIBY
Sequence: MNHFELFNLPVALDIDLASLKSNFLSLQQQYHPDKAADKDQALIKSSEINQAFKTLSQVDSRAAYLLALKKQDHHLDQSISDFEFLQSALELREQLDEATSSEHLRTLRLEVQQWIDGLVREFKIDYSEEDWAEARDTVRKLRFFQRVLNDIDKAEDQLLDDEDSFDLDDDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: SYP_THEFY
Sequence: MLLRMSNLFLRTLREDPADAEVPSHKLLVRGGFVRRTAPGVYSWLPLGKIVLENVAAVVREEMNRIGAQEVLLPALLPREYYEATGRWTEYGDTLFRLKDRKGADYLLGPTHEELFTLLVKGEYTSYKDYPVILYQIQEKFRDEARPRAGILRGREFHMKDSYSFDLDDEGLQRSYEAHRQAYIRIFDRLGLEYVIVKATSGAMGGSASEEFLAIAPTGEDTFVRSTGSDYAANVEAVVTPAPPERPIDGLPEARVHHTPNTPTIESLVEFLNNAGLGRTFTAADTLKNVMVKTRAPGEKEWELLGIGVPGDREVDMKRLEASLAPAEVALLDEEDFAKHPFLVRGYIGPGALQANKVRYLVDPRVVTGTAWVTGADKADHHVVDLVCGRDFTPDGTIEAAEVRDGDPAPDGKGTLYTARGIEIGHVFQLGRKYTDAFSLDALGPDGKPVRITMGSYGIGVSRVVAAIVEQSHDERGIIWPREVAPADVHVVGTGKGDQVEVALRISQELVDRGVRVLVDDRKGVSPGVKFTDAELLGVPTVLIVGRGLANGVVELRDRASGDRSEVSVDTVVDTIVNLVRG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_PSEMY
Sequence: MNQERVFKVLLGPHISEKATVLADKQGQFVFKVATDATKLEIKKAVESLFNVKVERVTTQNVLGKSKRTARGLGKRNDWKKAVISLQPGQDLDFTSSAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RECX_ECO55
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM14A_HUMAN
Sequence: MDLIGFGYAALVTFGSIFGYKRRGGVPSLIAGLFVGCLAGYGAYRVSNDKRDVKVSLFTAFFLATIMGVRFKRSKKIMPAGLVAGLSLMMILRLVLLLL
What is the function of this protein?
Inhibits apoptosis via negative regulation of the mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
What are the official names of this protein?
Transmembrane protein 14A.
What is the protein family that this protein belongs to?
Belongs to the TMEM14 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.
Protein: IDI_KLEP7
Sequence: MAGEHVILLDEQDQPAGMLEKYAAHTFDTPLHLAFSCWLFNQQGQLLVTRRSLGKKAWPGVWTNSVCGHPQQGETFEQAVTRRCRFELGVEISDIAPVHPAFRYRAVAPNGIVENEVCPVYAARVVSEVQPNDDEVMDYQWVDLATMLSALAATPWAFSPWMVLEAENRDARQALTDFVARLRG
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCB_MONBE
Sequence: MKYLERLTPSCWRIKPGFVPNMKVEGRFYVNKALEALMLEELQQFASARGVGGFLPAVKQIANVASLPGIVGASVGLPDVHSGYGFAIGNMAAFDMDDPEAIVSPGGVGFDINCGVRLLRTNLTLEDVEPVKEQLAQSLFDHIPVGVGSKGVIPMNAKDLEEALEMGMDWSLREGYAWAEDKEHCEEYGRMLQADASKVSARAKKRGLPQLGTLGAGNHYAEIQVVEEIYDKEAAAKMGINKKNQICVMIHSGSRGLGHQVATDALVAMEKAMKRDGIEVNDRQLACARIHSEEGQNYLKAMAAAANYAWVNRSTMTFLCRQAFAKQFNTTPEELDMHVIYDVSHNIAKTERHMVNGTERTLLVHRKGSTRAFPPHHPLIPVDYQLIGQPVLIGGTMGTCSYVLTGTDTGFRDTFGSTCHGAGRALSRAKSRRTLDYQQVLDKLDKKGIAIRVASPKLVMEEAPESYKDVTAVVDTCHAAGISKKVVKLRPIAVIKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: DPHB_HALMA
Sequence: MLTFVGLGLYDERSVTVAGRDAIRDADRVFAEFYTSRLIGTDIETLEDTLETSIERRDRAGIEQDPEPILEAAESEHVVFCTAGDTMVSTTHADLRLRAADRGIETRIVHGTTAQTAAGSLTGLQNYRFGKATTLPFEDAHGGDGVPDSVVATIEDNRDRDLHTLVYLDIKVDDPHWEESDDTYMTASQAATMLSEPFPDTLGVVVARAGSPDPLVAADTLDELATQTFGDPLHLLVIPGSLHPLEADTLESVAGAALE
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: HIS7_MYCTU
Sequence: MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRVSGVPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_PROM2
Sequence: MKRVALLVQYDGYHYSGWQKQKNATTVQEILESALFKITNHTVKTFAAGRTDAGVHASGQVVHFDIDSVIPGFSYSNILNNLLPSTIRILESVEVKNSWHACYSAVYRHYRYVINNGKFPNLFINNWSWHRYQKVLDEVLMLHASKTMEGEHDFFAFQKSGSNRRNSVTLIKNIDIKRVEDLILVDIKATGFLYGMVRLIVGQLVLVGEKKISSDIFIDRWVNKKKNDVKESAPAKGLCFVNAVYEENVFKKVNNNDFFPLFLINGFS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: IRL1_GINBI
Sequence: MGKSRILIIGATGYIGRQVAKASAALGHPTLILVRETTASNPEKAQLLESFKSSGITIVHGSLEDHASLVEAIKKVDVVISTVGGAQIADQLNIIKAIKEVGTIKRFLPTEFGNDVDKTSAVEPAKGLFALKVKIRRAIEAEGIPYTYVSSNCFAGYFLPNLGQPGLTAPPRDKIVIFGDGNAKAVFVKEEDIGTFTIKSVDDPRTLNKTLYLRLPANTFSFNELVALWEKKIGKTLEKVYVPEEQVLKTIAETPFPGNIIISIAHSIFVKGDQTNFEIGDNGVEGSELYPDVKYTTVDEYLNQFV
What is the function of this protein?
Oxidoreductase involved in lignan biosynthesis.  Catalyzes the NADPH-dependent reduction of phenylcoumaran benzylic ethers.  Converts dehydrodiconiferyl alcohol (DDC) to isodihydrodehydrodiconiferyl alcohol (IDDDC), and dihydrodehydrodiconiferyl alcohol (DDDC) to tetrahydrodehydrodiconiferyl alcohol (TDDC).  May regulate changes in lignin content and accumulation of flavonoids.
What are the official names of this protein?
Phenylcoumaran benzylic ether reductase IRL1, Isoflavone reductase-like 1, GbIRL1, IFR-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: RS5_METAC
Sequence: MAFDQDWVPKTRLGKLVVEGQVASMDEAIKSGLPIREPQIIDMLLPDLEDEVLDINMVQRMTDSGRRVKFRATVIVGNRNGYVGLGQAKDVQVGPAIRKAIDAAKLNITYIRRGCGSWECACGLPHTVPYEVTGKAGSVSVTLIPAPRGLGIAAGNTATKVLEKAGIKDVWTKTFGTTRSTLNFAKATYDALNQVNVVRLPVYYGKEEV
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PX12B_XENLA
Sequence: MAERGAHITTTSPLDDRPSIFEVVAQESLMAAARPALHHIVKVLAESNPARYGTLWRWFDELYTLLECLLQQHYLSWASASFSENFYGLKRVTLGKQVGQRNLARKEYWKSLLLLVLIPYLRIKLEKLVNSLREEEDYSIQNPTSFHKRCYKAILASYPFLKLGWEAWFLFYQLRYILWNGKHHSPLLRLAGVQLARLTMEDLRAMEKQEELTNTVSNVVSISQHIRSILKKALGAVTLSVSSSLSLGVFFLQFLDWWYSAENRETLKSLGNLPVPPPPIHFDLETYSPLLPKLRTVCPLCRKVRVNDTALGTSGYVFCYRCAYYYVKTHQRCPVSGYPTELQHLIKLYTPDG
What is the function of this protein?
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (PubMed:35931083).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity).  PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity).  When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Peroxisome assembly protein 12-B, Peroxin-12-B.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
Protein: YFDT_ECOLI
Sequence: MTTFTNKELIKEIKERISSLEVRDDIERRAYEIALVSLEVEPDEREAYELFMEKRFGDLVDRRRAKNGDNEYMAWDMTLGWIIWQQRAGIHFSTMSQQEVK
What are the official names of this protein?
Uncharacterized protein YfdT.
Protein: RECR_BURCH
Sequence: MKQPSALSALVEALRVLPGVGPKSAQRMAVHLMQHDREGAERLGRSLLFATEHLQHCEKCNTFTEAQICEVCSDEERDPTLLCVVETPADQIMLEQTMTYRGLYFVLMGRLSPLDGIGPKEIHFDRLVRRASDGVVKEVVLATNFTNEGEATAHYLGQTLKARGLAVTRLARGVPVGGELEYVDAGTIARAMLDRRTM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: COXX_BACMK
Sequence: MNHATSELHDESAVSIVPETTRLQDLSALVKMGIVNSNTLTVFTGFWLALHFNGLSVMDNLDKLFFTIVGSALIMAGVCCLNNYIDRDIDPLMERTKNRPTVTGKYKPGFALAFGLVILLLGFVFLLLTTPMAVLISFIGAFTYVVLYTLWTKRKYTLNTVVGSISGAVPPLIGWAAIDPSLNHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVQGFDITKRQIMIWTVCLLPLPFYMSGLGITFMVIATLLNIGWIALGLYGFRQQDDIKWSVKMFVYSLNYLTILFVSMIVVTFF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YDJC_BACCR
Sequence: MMIKLIVNADDFGLTEGTNYGIIDGHINGLVNSTTMMMNMPGTEHAVRLAKEYNLLGVGVHLVLTAGEPLLKDVPSLVGENGSFHKQSVVREGNINPEEVEREWTAQIEKFLSYGLTPTHLDSHHHVHGLPILHDVLERLAAKYNVPIRRCEEDRAVHPFSDVFYSDFYADGVTEDYFVKLKERVQGEQTVEIMVHPAYIDPELVKRSSYVMDRVKELRILTESELPEGIELVKF
What is the function of this protein?
Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
What are the official names of this protein?
Carbohydrate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family.
Protein: Y4503_PHOLL
Sequence: MAENQWVLYLLKTKSGMLYTGITTNIHRRFAQHENGKGAKSLRGKGPLQLVFSSYAGDRSNASQLEYQVKQLSKQQKERLVICQPVCIAEYLASIRNGQSVRSK
What are the official names of this protein?
UPF0213 protein plu4503.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: DCTA_YERE8
Sequence: MKASVFKSLYFQVLTAITLGVLLGHFYPELGAQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAIALLYFEIVSTIALLIGLVIVNVVQPGAGMNIDPATLDAKAVALYAEQASQQGIIPFLLDIIPGSVVGAFASGNILQVLLFAVLFGFALHRLGEKGQLIFNVIESFSRVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLVQLGQLIICFYITCVLFVVVVLGSIAKFNGFNIFKFIRYIKEELLIVLGTSSSESVLPRMLDKMEKAGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTHMDVIHQVTLLVVLLLSSKGAAGVTGSGFIVLAATISAVGHLPLAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWCNQLDNDQLQAVLSNKTLPNNEIKSSTSA
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.