PharMolix/UniProtQA huggingface dataset:
Protein: Y975_GRABC
Sequence: MNKKKDDCGGLSLPSDSVFCSLHANDSIWQHDKKVLRGGKASRDGLEAERIAAQALEADGWQILGRRLRTSAGEIDILAEMDGLLAIVEVKYRPTLSEAAHALGPRQRKRLIAAASYVLAQHPEYGTEGVRFDVIVVDMAGQVRRITDAFRLDEEGWP
What are the official names of this protein?
UPF0102 protein GbCGDNIH1_0975.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: SYL_SHEWM
Sequence: MQEQYQPSEIEAKVQQHWQDTKTFEVTEDENKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVARYQRLQGKNVLQPIGWDSFGLPAENAAIKNSSAPAPWTYENIDYMKNQLKMLGFGYDWSREIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQVQDGCCWRCDTEVVQKEIPQWFIKITDYADELLSDIDQLDEWPEQVKTMQRNWIGRSEGIEMTFQVADSDESFDIYTTRPDTVMGVTYVAIAAGHPLAEKAAANSPELAAFIEECKNADTTEAAMAAMEKKGVATGLYAIHPLTGKQVPIWAANFVLMNYGTGAVMSVPAHDQRDYEFAIKYGLAIEGVIKPEDAELDISEEAYTEKGVLFNSAEFDGLDFQAAFDAIDAKLTAEGKGKRQVNFRLRDWGVSRQRYWGAPIPMVTLADGTVVPTPEDQLPVILPEDVVMDGIQSPIKADKEWAKTQINGEDALRETDTFDTFMESSWYYARYCSPHADEMLDPAKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLRDIGLVNSDEPAKRLLTQGMVLADAYYYTNEKGARVWVSPADVTVQETDDKGRTVKAVDSHGNELVYTGMSKMSKSKNNGIDPQEMVDKYGADTVRLFMMFAAPPELTLEWQESSVEGAHRFIKRLWKVAHDHVAKGTTVSLDVKSLDAKQKELRRELHKTIAKVGDDIERRQMFNTAIASVMELMNRLQKAPTETEQDRALMQEALSAVVRLLYPIIPHTSFSLWKELGNEENIEDVRWPEADESALVEDSKLIIVQVNGKLRAKITVPADATKEAVEAQGFAEEGVIKHTEGKTVRKVIYVPGKLLNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDH_BOVIN
Sequence: MLTARLSRPLSQLPRKTLNFSDRENGTRGSLLLYSAPFVPVGRRTYAASVDPVGSKAVLITGCDSGFGFSLAKHLHSEGFLVFAGCLMKDKGSDGVKELDSMKSDRLRTVQLNVCKSEEVDKAAEVIRSSLEDPEKGLWGLVNNAGISTFGDVEFTSMETYKEVAEVNLWGTVRVTKAFLPLIRRAKGRVVNISSMMGRMANVARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYGGTERIQAIANKMWEELPEVVRQDYGRKYFDEKVARMESYCTSGSTDTSPVIKAVTHALTATTPYTRYHPMDYYWWLRMQIMTHFPGAISDRIYIH
What are the official names of this protein?
D-beta-hydroxybutyrate dehydrogenase, mitochondrial, 3-hydroxybutyrate dehydrogenase, BDH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Mitochondrion matrix.
Protein: Y2236_CERS4
Sequence: MNRICHIEIDQTSPIPPTAEIEQERQVAIFDLLEENSFALPAREGRAPAEGPFRLTLAIREGRLVFDIRSEEEETVGEFHLSLGPFRQVVKDYFQICESYFEAVKRLPPSQIEAIDMARRGIHNEGARVLKERLEGKAEVDIDTARRLFTLICVLHWG
What are the official names of this protein?
UPF0262 protein RHOS4_22360.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: BCCIP_CAEEL
Sequence: MGRVFKKKGGAKREAEEEKQEELVMRKKLRKEEEPEPVEDVEEDEDVSDEDDEDIDDEEEDEDEQNIMDFDFEAYPPSEDDRDGIVNMLTQTFLRTDIDLKAMSEGIIAKAPHGVVLTQAYDDEETEEDYMAYGLCTTVPLNDNKDDAPKFIKDLFTYVLNRAKKGAPTEIYKKIEEIQVSGDGKSALFVNERLLNFPTIVVPQIFGSIREDLSGFETKYKTIIYIQKLRIVETDGSEAKVGASSNGSSGVAGKKKGKMGKAEKKRAAAAALANAEIEFDNPEDRVLFEIKEGKEIHFDYPVHMDVEPGSKFHSTEKDGKKWNPFRRLVIMDDKRFDAFLKKGSDGIII
What are the official names of this protein?
Protein BCCIP homolog.
What is the protein family that this protein belongs to?
Belongs to the BCP1 family.
Protein: RDRP_I02A4
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPENHEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNDLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRIRDNMTKKMVTQRTIGKKKQRLNKKSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPDWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNELTKKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: UGPE_YERE8
Sequence: MIENRRGLDIFCHVMLIIGVLLILFPLYVAFVAASLDDTQVFQVPMTLIPGPHLWQNISHIWHAGVGNNSAPFGLMLFNSFVMAFAITVGKITVSMLSAYAIVYFRFPLRNLFFWLIFLTLMLPVEVRIFPTIQVIANLNMLDSYTGLTLPLMASATATFLFRQFFMTLPDELLEAARIDGAGAMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPILITSDASMGTAVAGIRSMISSSGAPTQWNQVMAAMILTLIPPVAVVLLMQRWFVRGLVDSEK
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpE.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LSPA_BRUAB
Sequence: MKRHAVWSSLFVVILAVLIDQGIKYLVESRMFYGQQIDLLPFLALFRTHNEGIAFSMLAWLHDGGLIAITLAVIAFVLYLWWTNAPERVFARYGFALVIGGAIGNLIDRVMHGYVVDYVLFHLPTWSFAVFNLADAFITIGAGLIILEEFLGWRRERISH
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS13_STAAN
Sequence: MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: Y2317_METFK
Sequence: MLIEIPEVLTKEQVAQCRQLMDAAEWVDGNVTSGSQSALAKNNMQLPEGSPVARQVGDLIQDALGMSPLFISAALPLKVFPPLFNRYEGGQAFGTHVDNAIRQLRGTNFRIRSDLSATLFFSEPEDYDGGVLTIEDTFGIQEVKLPAGHMVLYPSSSLHHVTPVTRGVRVSSFFWMQSMIRDDAQRTLLFQLDGSIQAIGAERGAGDPEVIRLTGVYHNLLRMWADS
What are the official names of this protein?
PKHD-type hydroxylase Mfla_2317.
Protein: PYRE_BACAA
Sequence: MKKEIASHLLEIGAVFLQPNDPFTWSSGMKSPIYCDNRLTLSYPKVRQTIAAGLEELIKEHFPTVEVIAGTATAGIAHAAWVSDRMDLPMCYVRSKAKGHGKGNQIEGKAEKGQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFTYELEAGKEKLEAANVASYSLSDYSALTEVAAEKGIIGQAETKKLQEWRKNPADEAWITA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: FTHS_RUEST
Sequence: MSYKSDIEIARAANKLPIQEIGAKLGMKNDDLLPYGHDKAKVSQEFINSVQGNEDGKLVLVTAINPTPAGEGKTTTTVGLGDGLNRIGKNAMICIREASLGPNFGMKGGAAGGGMAQVVPMEEMNLHFTGDFHAITSAHSLLSAMIDNHIYWGNEQEIDIRRVAWRRVVDMNDRALRQITASLGGVSNGFPRETGFDITVASEVMAILCLANDLKDLEKRLGDIIVAYRRDKTPVYCRDIKAEGAMTVLLKDAMQPNLVQTLENNPAFVHGGPFANIAHGCNSVIATKTALKVADYVVTEAGFGADLGAEKFMNIKCRKAGIAPSAVVVVATVRAMKMNGGVAKADLGAENVEAVKNGCANLGRHIENVKSFGVPAVVAINHFVTDTDAEINAVKEYVASHGVEAILSRHWELGSEGSAPLAEKVVELVEGGGANFGPLYPDEMPLFEKIETIAKRIYRADEVLADAKIRNQLKEWEEAGYGHLPVCMAKTQYSFSTDPNLRGAPTGHSVPVREVRLSAGAGFIVVVCGEIMTMPGLPRTPAAESICLNEEGLIEGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RR19_MESVI
Sequence: MARSLKKGPFVADHLLKKIEFLNVKKEKKVITTWSRGSTILPIMIGHTIAVHNGREHLPIFITDQMVGHKLGEFSPTRTFRGHTKSDKKSRRP
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMKL_YERE8
Sequence: MNSLFASTARGLEELLKSELEALGAHDCKIVQGGVHFQGDDRLMYQSLLWSRLASRILLPLNDFKVYSDLDLYLGVQAIDWPSIFGVDKTFAVHFSGVNDEIRNSQYGALKVKDAIVDSFTRKLDQRPTVAKQQPDIRVNVFLQRDMASVALDLSGEGLHQRGYRDLTGQAPLKENLAAAIIQRSGWQLGTPMADPMCGSGTLLIEAAMMASDRAPGLHREHWGFTAWNAFNQELWRELTTEAQVRARRGLQETTSRFFGSDIDRRVIEMARANARRAGVAELITFNANDVSKLVNPLPEGPVGTVISNPPYGERLDSEPALIALHNMLGRIMKASFGGWRLSLFSASPELLSCLQLRAEREFKAKNGPLDCVQKNYQLAANPQGAVGVQVAEDYANRLRKNVKKLDKWAKQQGIECYRLYDADLPDYNVAVDRYGSKVVVQEYAPPKTIDAQKARQRLFDVINATLAVLNLPSNQLVLKTRERQKGKNQYEKLAQKGEFLLVSEYNAKLWVNLTDYLDTGLFLDHRIARQMLGKMSQGKDFLNLFAYTGTASVHAGLGGARSTTTVDMSRTYLEWAEKNLRANGLTGQQHRLIQADCLSWLSNTDEQFDVIFIDPPTFSNSKRMETTFDVQRDHLVLMKELKRLLRRKGTIMFSNNKRGFQMDLDGIKALGLEAKEITAQTQSEDFARNRQIHNCWLVTHSHEEK
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_ECO5E
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSEIASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAAAHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PSTB1_HALMA
Sequence: MTENEMTSNDSTEPTPTTETAASSPDPSGDPLIEQSIDVEGTDSTAAETGKPVIESSDLNVFYGETQALQSIDLAIPEKQVTAMIGPSGCGKSTFLRCINRMNDLIDAARVEGDLHFEGKNVYDADVDPVALRRRIGMVFQHPNPFPKSIYDNVAYGLRIQDQTENIDEKVETALKRAALWDEVKDQLDKSALDLSGGQQQRLCIARAIAVDPDVILMDEPASALDPIATSKIEDLIEELAEEFTVVIVTHNMQQAARISDKTAVFLTGGELVEFDDTDKIFENPESQRVEDYITGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NU4LM_ZALCA
Sequence: MSMMYFNIFMAFTVSLVGLLMYRSHLMSSLLCLEGMMLSLFVMMSVTILNNHFTLASMAPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MTAP_RHORT
Sequence: MSEAYRQPVLGVIGGSGVYDIDGLEGARWQTVESPFGDVSDQILRGTLDGLEMAFLPRHGRGHVLAPSDVNYRANIDALKRAGVTEILSVSAVGSLAEDLPPGTFVIADQFIDRTFAREKSFFGKGLVAHVSMAHPVSAWLGDRVEEVLADLAIPHRRGGTYLCMEGPQFSTLAESNLYRQWGCHVIGMTNMPEAKLAREAEIAYCTVAMVTDFDCWHPDHDHVSVEAVVRVLLQNADKARSLVKAMPAKLKDRPYPLPDGSHRSLDNAIITHPDRRNPGMARKLSAVAGRVLG
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate (PubMed:23042035, PubMed:31950558).  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates (By similarity).  Also catalyzes the phosphorylation of 5'-deoxyadenosine (5'dAdo) to 5-deoxyribose 1-phosphate (PubMed:31950558).  Part of a bifunctional DHAP-shunt salvage pathway for SAM by-products (PubMed:31950558).
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: ACSA_MARMS
Sequence: MKSLYSATSNEAAKNANVSQAEFEKRYQESIENPDEFWGREGKRIDWFKPYTKVKNTSFKRGEVSIKWFEDGELNVAYNCIDRHLAKSANKVAYYCEGDKESDEKVAITYQTLHDEVGRLANLLKRQGVKKGDRVAIYMPMIPQAVYAMLACARIGAIHSVIFGGFSAHAIADRLNDCEVKLVITADEGRRAGNTIPLKHNVDMALDNNACPTVENVIVYRYTEKDVPWFEGRDLDWAVEVENESTECPAERMNAEDPLFILYTSGSTGKPKGVVHTTGGYLVYASLTHELVFDLKPDDVYWCAADVGWITGHSYMVYGPLANGTTSILFEGVPTYPDSGRIGRVVDKFDVTILYTAPTAIRALMAKGDEATRSSKRDSLRVLGSVGEPINPEAWSWYYSEIGNSSCPIVDTWWQTETGGMMMTPRIVQGDVKPGSCTGPLYGVQPALVDAQGVLQEEQGVLVEGGLVITDSWPGQARTVYGDHERFEQTYFSTFDGMYFTGDGASRDADGHYWITGRMDDVLNVSGHRLGTAEIESALVAHPSVAEAAIVGFPHDIKGQGIYVYVSAIAGVIPDEELTKSLKLFVRQEIGPIATPDLIQWTSKGLPKTRSGKIMRRILRKIAANEHDQLGDTSTLADPSVVDDLIENRLNV
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: DRRA_LEGPN
Sequence: MSIMGRIKMSVNEEQFGSLYSDERDKPLLSPTAQKKFEEYQNKLANLSKIIRENEGNEVSPWQEWENGLRQIYKEMIYDAFDALGVEMPKDMEVHFAGSLAKAQATEYSDLDAFVIVKNDEDIKKVKPVFDALNNLCQRIFTASNQIYPDPIGINPSRLIGTPDDLFGMLKDGMVADVEATAMSILTSKPVLPRYELGEELRDKIKQEPSFSNMVSAKKFYNKAIKDFTAPKEGAEVVSVKTHIMRPIDFMLMGLREEFNLYSEDGAHLSAPGTIRLLREKNLLPEEQIARIESVYNQAMSKRFELHAEHKKEHDEMPYSDAKAMLDEVAKIRELGVQRVTRIENLENAKKLWDNANSMLEKGNISGYLKAANELHKFMKEKNLKEDDLRPELSDKTISPKGYAILQSLWGAASDYSRAAATLTESTVEPGLVSAVNKMSAFFMDCKLSPNERATPDPDFKVGKSKILVGIMQFIKDVADPTSKIWMHNTKALMNHKIAAIQKLERSNNVNDETLESVLSSKGENLSEYLSYKYATKDEGREHRYTASTENFKNVKEKYQQMRGDALKTEILADFKDKLAEATDEQSLKQIVAELKSKDEYRILAKGQGLTTQLLGLKTSSVSSFEKMVEETRESIKSQERQTIKIK
What is the function of this protein?
Virulence effector that plays a key role in hijacking the host vesicular trafficking by recruiting the small guanosine triphosphatase (GTPase) Rab1 to the cytosolic face of the Legionella-containing vacuole (LCVs).  Acts as a GDP-GTP exchange factor (GEF) for the small GTPase Rab1 (RAB1A, RAB1B or RAB1C), thereby converting Rab1 to an active GTP-bound state, leading to the incorporation of Rab1 into LCVs.  Also shows RabGDI displacement factor (GDF) activity; however, this probably represents a passive activity following the GEF activity.  Also acts as an adenylyltransferase by mediating the addition of adenosine 5'-monophosphate (AMP) to 'Tyr-77' of host RAB1B, thereby rendering RAB1B constitutively active.  Also has adenylyltransferase activity towards Rab6 and Rab35.  Also displays guanylyltransferase activity by mediating the addition of guanosine 5'-monophosphate (GMP) to host RAB1B in vitro; however such activity remains uncertain in vivo.  Specifically binds phosphatidylinositol 4-phosphate (PtdIns(4)P) lipids on the cytosolic surface of the phagosomal membrane shortly after infection.
What are the official names of this protein?
Multifunctional virulence effector protein DrrA, Defects in Rab1 recruitment protein A.
What is the protein family that this protein belongs to?
Belongs to the DrrA family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Translocated into the host cell via the type IV secretion system (T4SS). Membrane association is mediated by PtdIns(4)P-binding.
Protein: HSLV_SOLM1
Sequence: MQLRGTTIVAVRTEAGVAVAGDGQVTLGQAIAVKHTARKVRRMYKDKVVIGFAGATADAFTLFERFEAKLEEFGGNLVRASVELAKDWRKDKYLRRLEAMMIVADAGNVLILSGTGDVIEPDDGVAAIGSGGPYAMAAARALLRNTELSAREIVEKSMAIAAEMCVYTNDQLVVETLEKPA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMC_AGRFC
Sequence: MSGGGDATVSAELIAARKRLQAAGVADPLVDARLLIADVTGFSLTDFVMKPEHPVTQDESARIAAMIERRAEGEPVHRILGHREFHGLDLLLSKETLEPRPDTEVLVDTLLPALKEAVSRKGSARILDLGTGTGAICLALLKECAQASGIGSDISADALETAAKNAARNGLDSRFETIRSNWFEKISGRFDIIVSNPPYIRTDIVATLDPEVRNHDPMAALDGGQDGLAPYRLIAADAGRFLVENGTVGVEIGFDQRLDVSAIFASHGFSLLDAVKDYGGNDRVLTFRR
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: DOF43_ARATH
Sequence: MDNFNVVANEDNQVNDVKPPPPPPRVCARCDSDNTKFCYYNNYSEFQPRYFCKNCRRYWTHGGALRNVPIGGSSRAKRTRINQPSVAQMVSVGIQPGSHKPFFNVQENNDFVGSFGASSSSFVAAVGNRFSSLSHIHGGMVTNVHPTQTFRPNHRLAFHNGSFEQDYYDVGSDNLLVNQQVGGYVDNHNGYHMNQVDQYNWNQSFNNAMNMNYNNASTSGRMHPSHLEKGGP
What is the function of this protein?
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
What are the official names of this protein?
Dof zinc finger protein DOF4.3, AtDOF4.3.
What are the subcellular locations of this protein?
Nucleus.
Protein: SURE_HISS2
Sequence: MHILLSNDDGIQAEGIKTLAKELRKFAQVTVVAPDRNRSAASSSLTLVEPLRPMKLDNGDYSINGTPADCVHLALNGFLSGQIDLVVSGINAGVNLGDDVIYSGTVAAALEGRHLSLPAIAVSLDGRQHYESAAIIVSQLIPKLYGRLLKSREIININVPDLPYSEIKGIKVCHLGYRAAAADIIKQKDPRGEEIYWIGPIGLAENESEGTDFHAVKNGYVSITPIQTDMTAYHSMTALQQWLDKE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROS_HYPSF
Sequence: MALSNSNSTTATVTLPDTLRFWPWQRHINPHYSACKKASSEWCESFKAFSPQAQRAFNKCDFNGCRIGCDLMNLFFIIDEHTDIASAETARTQANIIMEAIRDPEMPRSENEWVGGKAAQQFWLNATKSATPSAHRRFIDAFQMYMDAVVQQAADRSKNYVRDIDDYFVVRRDTIGAKPSFAICELYLNLPDSVMEHPVIMKLTELCIDVIIIGNDLCSYKVEHEHGDDGHNLITVVMNQFKITPQEAMNYISDLHDKLAVQFLDEWKNIPTFGGPLDLEVRTYCHGLGNWVRANDSWSFESERYFGKRGIEIQTTRQIEMNIQSHL
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to delta(6)-protoilludene.
What are the official names of this protein?
Delta(6)-protoilludene synthase HYPSUDRAFT_138665, Sesquiterpene synthase HYPSUDRAFT_138665, Terpene cyclase HYPSUDRAFT_138665.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RL27_SERP5
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGTNVGCGKDHTLFALKDGKVKFEVKGPSNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL36_THET8
Sequence: MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, Ribosomal protein B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: UVRA_VIBVY
Sequence: MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPDHKVPLAAQTISQMVDKVLELPEGAKMMLLAPIVKERKGEHVKTLENLAAQGFIRARIDGETCDLTDPPTLELHKKHTIEVVVDRFKVRGDLQQRLAESFETALELSGGIAVIAPMEGDGEEIVFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDPERVIQDANLSLAQGAIRGWDQKNYYYFQMLTSLAEHYDFDLHAPFNSLSKRIQEVILKGSGRTEIEFKYINDRGDIRLKRHPFEGILNTLERRYRDTESNSVREELVKYISTKPCTSCGGTRLRLEARNVFINDTTLPQIVELSIADALTFFATLKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLTHLRDLGNTVLVVEHDEDAIRCADHVIDIGPGAGVHGGQVVAEGTMAEILANPDSLTGQYLSGAKQIIVPTQRTPRDKNKTVELIGASGNNLKEVNLSVPVGLFSCITGVSGSGKSTLINDTFFKIAHTQLNGATTAQPAPYKSIKGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFSGTQESRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVHYKGKSIDEVLEMTVEDAHEFFAPVPVIARKLQTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHRLRDHGNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGEIIAQGTPEDVAQIEGSHTARFLKPMLK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.