PharMolix/UniProtQA huggingface dataset:
Protein: RUBR_CLOAB
Sequence: MKKYVCVVCGYIYDPAEGDPDNGVNPGTSFEDIPDDWVCPLCGVGKDQFEPSEE
What is the function of this protein?
Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide.  Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.  Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2 in which Rd serves as the proximal electron donor to the FDPs that exhibit H(2)O-forming NADH oxidase activity.  Also functions as the proximal electron donor to the Dfx and revRbr proteins that display superoxide reductase (SOR) and NADH peroxidase activity, respectively.  Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C. acetobutylicum, an obligate anaerobic bacterium.
What are the official names of this protein?
Rubredoxin, Rd.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
Protein: NUOB_PARDP
Sequence: MMTGLNTAGADRDLATAELNRELQDKGFLLTTTEDIINWARNGSLHWMTFGLACCAVEMMQTSMPRYDLERFGTAPRASPRQSDLMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRRIRRTGTLVR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NADH dehydrogenase I, subunit 6, NADH-quinone oxidoreductase subunit 6, NQO6, NDH-1 subunit B, NDH-1, subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATG23_YEAS7
Sequence: MELNQVLEKKEQILQYLGTLVGLHEKALSDVNSASQVTSIRKDITICLNDLCRINDLLVSHDGLLKREIGSLLRDKQELLELNEREQLLWKERKSWHIEQETDAAPADYVIDKDAIITISSHHRTSLNKYIESVGAENTILSNTDDSDAMIEEVQNAESSADQMIRNYKLLQLSHKQAKSEIIRLETLLRDFKKDNKFIEEELKRQSGRIRSEMGNIDFHLSKIEESKHQLMKRIGFESPLTQEKSLSEKIFNLRLSSADEDYNERQTINMKNFVHMKDLIELKIEDLQEQLTRNKNESSTVLTQRELWLDCQKKVGDLESKLITKLRSSSNSKIPPNEMSEMINSTIQYLNNLLDSSDEKLTTTLISNERDVLSKACEELHSESTTPQDGSSALPSKPIDIHKSHKGSNASSNLKQPSTPSFLVASKSPPKIGISESVVNANKNDAISKKVE
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy.  Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9.  Also plays a role in regulation of filamentous growth (By similarity).
What are the official names of this protein?
Autophagy-related protein 23.
What is the protein family that this protein belongs to?
Belongs to the ATG23 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein. Note=Found in pre-autophagosomal structure and other punctate structures. Correct localization of ATG23 to the membranes is strictly dependent of ATG9. Cycling through the pre-autophagosomal structure and correct location to other punctate structures is ATG1- and ATG13-dependent (By similarity).
Protein: DAPD_ERWT9
Sequence: MQQLQNVIEAAFERRADITPVNADTAIREAVSQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRFYDKVPMKFADYDEARFKKEGFRVVPPAAVRQGSFIARNTVLMPSYVNIGAYVDEGSMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIGQSTKIYDRETGEVHYGRVPAGSVVVSGNLPSKDGSYSLYCAVIVKKVDAKTLSKTGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAP_BRUSI
Sequence: MPNIDLPTLEAFVHAIPQNYKGPGGAVAVVRNGEIVLRHAWGFADLAARKAMTPETRMPICSVSKQFTCAVLLDCIGEPEMLDSALAAYLDQFEDGRPAVRDLCNNQSGLRDYWALTVLCGAAPEGIFLPDQAQNLLRRLKTTHFAPGTHYSYCNGNFRILADLIEQHTGRSLADLLAERIFAPAAMKTAELIPDTALFNECTGYEGDTVRGFLPAINRIHWLGDAGICASLDDMIAWEQFIDRTRHDENGLYRRLSSPQTFADGAPAPYGFGLKFEETGGKRLTGHGGALRGWRCQRWHCADERISTIVMFNFEGNASDAALKMMNAALGIPPAKPVRAQANPGWFGSWLNPETGLVLSLEDAGGGRMKARFGTGPEIMDISGENEAQSSMTTLRRDGDMIHLARKDENLHLAMHRLKGEARQDIAGRYRSDELEADLLLVSEGGAIYGAFEGFLGKSDMYPLYAAGPDVWLLPVQRSMDAPSPGEWKLVFHRDAAGRITGVTVGCWLARGVEYKRL
What is the function of this protein?
Hydrolyzes N-terminal residues in D-amino acid-containing peptides.
What are the official names of this protein?
D-aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family.
Protein: MSRA_YERPB
Sequence: MQNVDNTAVIDAANALPGRLTSIPVSPLHAVHGHSMTYIPEGMDLAFFAMGCFWGAERLFWQQPGVYSTAAGYSGGHTPNPTYHEVCSGRTGHAEVVRVVFDPAVISYQQLLQIFWENHDPAQGMRQGGDVGTQYRSAIYVLTPEQEEQAHKSRERFQQAMEKAGDQRVITSEITVALPFYYAEDDHQQYLHKNPHGYCGLGGIGVCLPPNV
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TRMD_SALSV
Sequence: MFIGIVSLFPEMFRAITDYGVTGRAVKKGLLNIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGVDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVLGHEASAIEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_BURO0
Sequence: MKTVLIALLRFYKVAVSPMLGNRCRFYPSCSDYAREAIQYHGAARGTYLAVRRVCRCHPFSAGGVDLVPPPNSDTRARGEADARSHRL
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
Protein: RUVA_RICAE
Sequence: MIGQLSGKVDAQGDDYVIIDVNGVGYLVYASGKTLGKLAEGEFYKLFIETHVREEHIHLYGFLNLEEKIFFNLLQSVNGIGTRMALFILSSLTPSDIQIAVNNEDKNIFKAISGVGAKLAERIVLELKGKVAKISSGSAIIKESLNIKHITPVASNEVIKALVNLGFSRFEAQNAVQGIITQNPEISIDELIKTALKNRNSNF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PSBZ_SORBI
Sequence: MTIAFQLAVFALIATSSVLVISVPLVFASPDGWSNNKNVVFSGTSLWIGLVFLVAILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: RUVB2_XENLA
Sequence: MATMAATKVPEVRDVTRIERIGAHSHIRGLGLDDALEPRQVSQGMVGQLASRRAAGVILEMIKEGKIAGRAVLIAGQPGTGKTAIAMGMAQALGSDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEVQIDRPATGTGAKVGKLTLKTTEMETIYDLGTKMIESLTKEKVQAGDVITIDKATGKITKLGRAFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIECFSFLNRALESDMAPVLIMATNRGITRIRGTNYQSPHGIPIDLLDRLLIISTSPYNEKETKQILKIRCEEEDVDMSEDAYTVLTRIGLETSLRYSMQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFMFNEMKTDTMDTS
What is the function of this protein?
Has single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5' to 3') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity).  Proposed core component of the chromatin remodeling INO80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding (By similarity).  Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway where it negatively regulates expression of ER stress response genes (By similarity).
What are the official names of this protein?
RuvB-like 2, Reptin.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus. Dynein axonemal particle.
Protein: GPDA_CHESB
Sequence: MSRHWTIAVLGAGAWGTALALTMQRAGHGARLWARDQNLVREINNARSNSRYLPGVKIDPAVLATDDMAAALEGADCVLAAIPAQSLRSVLAVAGTALKAHIPVVLCAKGIERETGQLMSEAARQALPENPLAALSGPSFAADLARGLPTAVTVAAQDGALAADLAKKLSAPNLRCYSSDDLMGVELGGALKNVLAIAAGATSGAGLGASAVAAITTRGFVELRRIGAAFGARAETLMGLSGLGDLILTCNSPQSRNFAYGAALGRGERLDNLPLAEGVFTASIAARMVSERGLEAPIIETVNGMLNGGLTVHAAMQALLARPLKSE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_ACIAD
Sequence: MPVMASYSTNEFKQGLKVMLDGNPCSIMENEYVKPGKGQAFNRVKLRNLKTGKVLEKTFKSGDSLEAADIVEVEMDYLYNDGELWNFMDPVTFEQIAADKVAMGDAAKWLKDDSNEKCSIMLFNGVPLNVSAPNFVVLKIVETDPGVRGDTSGGGGKPAKLETGAVVRVPLFVQQEDSVRVDTRTGEYLERA
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-37 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KMCP1_XENTR
Sequence: MTALNWKPFIYGGLASITAECGTFPIDLTKTRLQVQGQANDAKYKEIRYRGMLHAIVRIWKEEGVKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFVDCPEDETLVINVFCGVLSGVVSSCIANPTDVLKIRMQAQGSLIQGGMIGNFINIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLASFTCGLAGALASNPVDVVRTRMMNQRSIRNVSNSSYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKKLNL
What is the function of this protein?
Probable transporter.
What are the official names of this protein?
Kidney mitochondrial carrier protein 1, Solute carrier family 25 member 30.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1077_MYCTO
Sequence: MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAVPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGIGTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR
What are the official names of this protein?
Putative cystathionine beta-synthase MT1108, Beta-thionase, Serine sulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: DAPF_SPHAL
Sequence: MADRFTKMHGLGNDFVVIDARVAPVEMTPARAHAIADRRHGIGCDQLILLEPSTSADVKMRIFNADGGEVEACGNATRCVATLIGKPAVIETLAGMLRVTPADGGAEVTLGEPVFDWDHIPLAMPMDTRDMPVAWDELEHGAAVNVGNPHIVFFVPEADAVALDQLGPRIETDPLFPERVNVNVASLDGENQLQLRVWERGVGLTQACGTGACATAVAAIRAGLVRSPVTVALPGGDLVIRWAPGEPIVMSGAATRVFDGETDWAQFG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_PELHO
Sequence: MKNVTDSFVSLGRWPSAGSFGLNTDILATNPINLSVVLGVLIFFGKGVLNDLLDNRKQRILNTIRNSEELRGGAIEQLEKARARLRKVKTEAARFRVNQYSEAEREKLNLINLTYKSLEDFENYKNDSIRFEQQRAIHQVRQRVFQQALRGALETLNSCLNKELHLRTISANIRLFRSMKELTN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL28_BORPA
Sequence: MARVCQVTGKGPMVGNNVSHANNKTKRRFLPNLQSRRFWVESENRWVRLRVTAKAIRTIDKNGIDAVLADLRARGEAV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: HXD13_HUMAN
Sequence: MSRAGSWDMDGLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAAAPPSAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS
What is the function of this protein?
Sequence-specific transcription factor that binds gene promoters and activates their transcription (PubMed:24789103).  Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (By similarity).
What are the official names of this protein?
Homeobox protein Hox-D13, Homeobox protein Hox-4I.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYND_ASPFU
Sequence: MSVAKSIAAVLVALLPGALAQANTSYVDYNVEANPDLTPQSVATIDLSFPDCENGPLSKTLVCDTSARPHDRAAALVSMFTFEELVNNTGNTSPGVPRLGLPPYQVWSEALHGLDRANFTDEGEYSWATSFPMPILTMSALNRTLINQIATIIATQGRAFNNVGRYGLDVYAPNINAFRSAMWGRGQETPGEDAYCLASAYAYEYITGIQGGVDPEHLKLVATAKHYAGYDLENWDGHSRLGNDMNITQQELSEYYTPQFLVAARDAKVHSVMCSYNAVNGVPSCANSFFLQTLLRDTFGFVEDGYVSSDCDSAYNVWNPHEFAANITGAAADSIRAGTDIDCGTTYQYYFGEAFDEQEVTRAEIERGVIRLYSNLVRLGYFDGNGSVYRDLTWNDVVTTDAWNISYEAAVEGIVLLKNDGTLPLAKSVRSVALIGPWMNVTTQLQGNYFGPAPYLISPLNAFQNSDFDVNYAFGTNISSHSTDGFSEALSAAKKSDVIIFAGGIDNTLEAEAMDRMNITWPGNQLQLIDQLSQLGKPLIVLQMGGGQVDSSSLKSNKNVNSLIWGGYPGQSGGQALLDIITGKRAPAGRLVVTQYPAEYATQFPATDMSLRPHGNNPGQTYMWYTGTPVYEFGHGLFYTTFHASLPGTGKDKTSFNIQDLLTQPHPGFANVEQMPLLNFTVTITNTGKVASDYTAMLFANTTAGPAPYPNKWLVGFDRLASLEPHRSQTMTIPVTIDSVARTDEAGNRVLYPGKYELALNNERSVVLQFVLTGREAVVFKWPVEQQQISSA
What is the function of this protein?
Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable exo-1,4-beta-xylosidase xlnD, 1,4-beta-D-xylan xylohydrolase xlnD, Beta-xylosidase A, Beta-xylosidase xlnD, Xylobiase xlnD.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NIFT_AZOVI
Sequence: MPSVMIRRNDEGQLTFYIAKKDQEEIVVSLEHDSPELWGGEVTLGDGSTYFIEPIPQPKLPITVRAKRAGEA
What are the official names of this protein?
Protein NifT.
Protein: ACEK_POLNA
Sequence: MFPQRLDSTVAYAIAKAMIDGFNRHYRLFRTESARAKHRFETADWHGQQRAQRERIEFYDLRVREASIRLEREFKAGEQPMDVWHQVKLHYIGLLVNHHQPELAETFFNSVTTKILHRSYFQNDFIFVRPAVSTEYIENQEPTAQPTYRAYYPTQGNMHETLVKLVEDFGLCREFEDLRRDAGYVAEAMAARLGDVKLRANFQIQVLSGLFFRNKGAYVVGKIINGFGEIPFALPILHRQPAPGQVLPADGKGISSQSDAGKLVIDAALFGEDDLLILFSFARAYFMVDMGIPSAFVQFLRSMMPRMPRAEIYNALGLAKQGKTLFYRDFLHHLRHSTDKFRIAPGIKGMVMLVFDLPSFPYVFKVIKDYYPPQKDTTREQIKGKYLLVKQHDRVGRMADTQEYSEVAFPRERFSDELIAEIEKFAPSQLEISDRDGDGQMEVIIKHVYIERRMIPLNIYLQEAFDFGVAEPAARDQIERAVVEYGNAIKDMVAANIFPGDMLWKNFGITRHGKVVFYDYDEIEYITDCKFRKVPTPRNEEDEMSGEVWYSVGPKDVFPETFGPFLLGNDAVREVFMKHHADLLDAAFWQRHQARIQAGHVYDVFPYDQQKRFAVMHGPARAG
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_ACTPJ
Sequence: MAKLTKKMKAIKAGVDSTKAYEINEAIAVLKQFATAKFVESVDVAVNLGIDPRKSHQNVRGATVLPHGTGRTARVAVFTQGENAEAAKAPGADLVGMEDLAEQIKKGEKNFDVVIPSPDAMRVVGQLGQVLGPRGLIPNLKVGTVTPNVVEAVKNAKSGQIRPRNAKNGIIHTTIGKADFAPEQLKDNLVALLAALNKAKPTTVKGIFIKKVSISTTMGAGVAVDQASL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ENGB_PSEMY
Sequence: MLPKNPIIGLCQQASFLISAAKVDQCPEDSGLEVAFAGRSNAGKSSALNTLTHASLARTSKTPGRTQLLNFFRLDDERRLVDLPGYGYAKVPIPLKQHWQKHLEAYLGSRESLCGLVLMMDIRHPLTEFDRMMLDWSVASGMPLHILLTKADKLAFGAAKNALLKVRQEIRKQWGEGISIQLFSAPKRMGVEEAQMVLAGWLDLLPQEDEESAEEA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PURL_SULIK
Sequence: MGLNLLPIEMDDIRKRLDREPNEIEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGIKDWQDAGAVDIGDGWAIVIKVESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDMIRVGNLKIRKNVWLLKNIIAGIAAYGNSIGVPVVGGELSFDDTYNDNPLVDVAAIGIVRKDKIKPSIVDKAGLKLVLAGLTGIDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDITLEIADKVEAIKDLGGGGLAVAVTEMANGLGAIVDIEKIPLRVKNMNPADVIISETQERMLYAVEEKNVEEVCKAFEEYEYPCSVIGEITSEPIIKFRYFGKDLVSLPTNALLEPPKFLWPIKNVRKNVEEKNVDLPLESTIYTVLSHPDLVSKEWVYSQFDYEVNTSTVVKPGDANGAVVSLPNGKLLAIKADGNPDLCSEDAYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKPEVYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENSQGKPIKPTPLIVMAGLVQGKLLKNRVEDSSYVVLLGYTRKELGGSLLSKIFKVPSQAPKVRLQEDLLSSEVVIDAINEEKITFAKDISRGGLAASLFNIIVHGYGVEISTKSILSDTDNVVENLFSESSGRFVILTNEPEWIVEKSRSKGIVASIIGKVNKKTSILTIDNTDYDLKTIVNNYFNFLEEVIGNG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_PHOV8
Sequence: MGFNEFIGKLFGNKATRDMKEIKPWVDKIKAVYPEIAKLSNDELRAKTVELKKYISDSAAEEQKKIEELKGTIETTELEDREGIFAQIDKLEKEVLEKYEKALDDVLPQAFAIVKDTARRFSENPELVVTATDFDRELAAQGKDFVRIEDDKAIWQNHWIAGGNDMVWSMVHYDVQLFGGVVLHKGKIAEMATGEGKTLVATLPVFLNALTGNGVHVVTVNDYLSKRDSEWMGPLYQFHGLSVDCIDKHQPNSDARRRAYMADITFGTNNEFGFDYLRDNMAVSPKDLVQRKHNYAIVDEVDSVLIDDARTPLIISGPVPKGEDQLFEQLRPLVERLFEAQKKLATQYLADAKRLIASDDKKDQEEGFLALFRSHKALPKNKPLIKFLSEQGIKAGMLKTEEIYMEQNNKRMPEATDPLYFVIDEKQNSVDLTDKGIDLITGNAADPTLFVLPDITSQLSALENETDLTEEEKLAKKDELMTNYAIKSERVHTINQLLKAYAMFEKDDEYVVIDGQVKIVDEQTGRIMEGRRYSDGLHQAIEAKEGVKVEAATQTFATITLQNYFRMYHKLSGMTGTAETEAGELWDIYKLDVVVIPTNRPIARKDMNDRVYKTKREKYKAVIEEIEEMVKEGRPVLVGTTSVEISEMLSKMLAMRKIEHNVLNAKLHQREADIVAQAGQKSIVTIATNMAGRGTDIKLSPEVKAAGGLAIIGTERHESRRVDRQLRGRAGRQGDPGSSVFFVSLEDDLMRLFSSDRIASVMDKLGFKEGEMIEHKMISNSIERAQKKVEENNFGIRKRLLEYDDVMNKQRVAVYTKRRHALMGERIGMDIVNMIWDRCAYAVELGDFDNVKMEILQTLAMEVPFTEEEYNKMRKEDLAEKTFEAAMNNFKRKTDRMAQIANPVIKQVYEMQGHMYENIMIPITDGKRLYNISVNLKAAYETEGKEIVKSFEKAILLHTIDDAWKENLRELDELKHSVQNASYEQKDPLLIFKLESVNLFDNMVNKINNNTISVLMRGQIPVQEPEQVREAAPEPQAPRQQYREEKQDLSDPHQQAAAEHDTREVKREPVRAEKTVGRNDPCPCGSGKKYKNCHGQNA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RNZ_PROM0
Sequence: MNITFLGTSSGVPSLTRNVSSLALKLSQSSEVWLFDCGEGTQHQIMKSNIKSSQIKKIFITHMHGDHIYGLPGLLATLGLSGNSEGIQIYGPSGLRSFINSSLKSSFCKLSFPLNFVEVENFASENKILFENNKIKVNCACLKHKIPAYGYRVSEKDKPGIFDIKKAESLKIAPGPIYSELQQGKKVVLADGRTFDGKEFCGPPRKGESFVYCTDTVFSESAVSLSKNADLLVHESTFSVEDESMAYEKLHSTTIMAAKTALLSNTKKLIITHLSPRYTNKNAITPSDLLKEAQKVFPNTYLAKDFLTAEIK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.