PharMolix/UniProtQA huggingface dataset:
Protein: FPS_DICDI
Sequence: MNNQSLQRAAMISEHLAPTSELNMNQTSAPIKTAKEELADFVEIFPILTNEILKELPGMDMPPQTIAWVEKMINVNVSGGKMNRGLTVLHSLQLLVEGRQLSRSEIFLANVLGWCVEWLQAFFLVADDIMDQSITRRGQPCWYRQANPISNNGTIGSIAINDSFILESCIYILIKKYFRNEPYYADILDIFHETSYQTELGQLLDLTTQPNRGDFSLFTLNTYRRIVKYKTAYYSFYLPVALAMLMAGITSTPAFSTAKDILLPMGEFFQVQDDFLDCYGSPAVIGKIGRDIEENKCSWMICQAILNGTPEQINLLKKHYGLDNPTDVELVKKIYGEIGLKKIFKDYEDESYAFLISKIKSVRIMPQEVFIKLLSKIYKRDL
What is the function of this protein?
Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a sterol precursor.  Involved in the inhibition of cell growth.
What are the official names of this protein?
Farnesyl diphosphate synthase, Dfps, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMY_METHJ
Sequence: MTSFTVIGHTACTDASFPLDDLPGKGGRMDLLCRAVASSLFLSHGIREDTTCDIMLLGQPHPGRIIRFDGSALRSLSPDERNIASSIKRALAIPAGKTFREAGPGLLTRKGTLADQLSEKHYAVLDESGVDIRKVATEELPDAFLLSDNRNFSDDEMELIRDIPKYSLGPAIVHADHAIVLILNEIDRRRSGWI
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTE_ECOL6
Sequence: MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPGSVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELNSAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAVEQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQDFLRMKEEVASGQIKQVQGSTPVQLNLENGKRYGQTGTLKFSDPTVDETTGSVTLRAIFPNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ
What is the function of this protein?
Part of the tripartite efflux system MdtEF-TolC, which confers resistance to various compounds.
What are the official names of this protein?
Multidrug resistance protein MdtE.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: SYC_THEPD
Sequence: MLRVYNTLSRSLEVFEPVEEGRVSIYVCGPTVYDYSHVGHARTYVAFDVIKRYLRLRGYDVVHVQNITDIDDKIINRARDEGRDWREIVDEYTKDYLEALQKLRVLVDVHPRVTEHISEIIDFVQKLIDSGHAYVAPSGSVYFDVDTYPDYGRLSGRLDKKMWSQEEFASEKKNPYDFALWKARKPGEPYWDSPWGPGRPGWHIECSVMSSKYLGRRFDIHGGGTDLIFPHHENERAQSEALFGEKPWVKYWMHTGMLQVRGEKMSKSLKNIVPLRDLFRSYDPLVVRLWLATAHYRTVLQFSDEVLEQAKSNLQRLRGAVQLLKNLAKEVEPEGRLSDWELGVFREMLDARREFYASMDDDFNASGAFAAVMKLTGLVYSQVSAKPTYLLVLRALRLFEEFNRVLGVLDEDLALGAAEVLPVDELLDLIVEVRAKLREQKNYELADYIRSKLSSLGVQLMDQGEKTRWILTRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_THENN
Sequence: MCELKELERELQPRQHLWYFEYYTGNNVGLFMKMNRVIYSGQSDIQRIDIFENPDLGVVFALDGITMTTEKDEFMYHEMLAHVPMFLHPNPKKVLIIGGGDGGTLREVLKHDSVEKAILCEVDGLVIEAARKYLKQTSCGFDDPRAEIVIANGAEYVRKFKNEFDVIIIDSTDPTAGQGGHLFTEEFYQACYDALKEDGVFSAETEDPFYDIGWFKLAYKRISKVFPITKVYLGFMTTYPSGMWSYTFASKGIDPIKDFDPEKVRKFNKELKYYNEEVHVASFALPNFVKKELGLM
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOPA_SALDC
Sequence: MKISSGAINFSTIPNQVKKLITSIREHTKNGLASKITSVKNTHTSLNEKFKTGKDSPIEFALPQKIKDFFQPKDKNTLNKTLITVKNIKDTNNAGKKNISAEDVSKMNAAFMRKHIANQTCDYNYRMTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLSLQATSSPSSPADWAKKLTDAVLRQKAGETLTAADRDFSNADFRNITFSKILPPSFMERDGDIIKGFNFSNSKFTYSDISHLHFDECRFTYSTLSDVVCSNTKFSNSDMNEVVLQYSITTQQQPSFIDTTLKNTLIRHKANLSGVILNEPDNSSPPSVSGGGNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTIDSLPDKYSQEKVQAMEDLVKSLRGGRLTEACIRPVESSLVSVLAHPPYTQSALIREWLGPVQERFFAHQCQTYNDVPLPTPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMTGVDCTDGTRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSSDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDTAWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQATQRRFGELIDIILSTEEHGELNQQFIAATNQKHSTVKLIDDASVSRLATIFAPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALMQKAWELSPAIFPSSEQFTDWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLSWA
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway.
What are the official names of this protein?
E3 ubiquitin-protein ligase SopA, HECT-type E3 ubiquitin transferase SopA, Salmonella outer protein A, Secreted effector protein SopA.
What is the protein family that this protein belongs to?
Belongs to the SopA E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host cell. Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cell.
Protein: ATPB_CORGB
Sequence: MTTALEEQNAQQAATAGRVVRVIGAVVDVEFPRGELPALYNALTVEVTLESVKKTVVLEVAQHLGDNLIRTIAMAPTDGLVRGAAVTDTARPISVPVGDVVKGHVFNALGDCLDDVSLNNNPEIERWGIHREPPSFDQLEGKTEILETGIKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMITRIAREFSGTSVFAGVGERTREGTDLFLEMEEMGVLQDTALVFGQMDEPPGVRMRVALSGLTMAEYFRDVQNQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGVLQERITSTKGRSITSLQAVYVPADDYTDPAPATTFAHLDATTELDRSIASKGIYPAVNPLTSTSRILEPAIVGERHYEVSQRVIGILQKNKELQDIIAILGMDELSEEDKITVARARRIERFLGQNFFVAEKFTGLPGSYVPLTDTVDAFERICNGDFDHYPEQAFNGLGGLDDVEAAYKKLTGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LDH_FERNB
Sequence: MKVSIYGAGRVGVSIAFSLLHTSLVDEMVLIDIDKKRAEGEALDLLHSSSMFKSCNIWAGDSKDIEDSDFIVITAGRSQRPGETRLELLGDNVRIMKEISEDIVKYSPNSIIINVTNPVDVLTYFIWQFTNLPSQRVIGTGTTLDTARLRVLLSQQCGISPASIHAYVIGEHGDSEFVPFSNATIGGLKLIDYCKLCENNSEQGFCLNLKIIEEKVRKAAYEIIERKGATNLAIGAVTARLISSMWRNEKRVWTISVLVDGIYIGYPSVIGKSGVEKVLRLNLSEDEEKKFQYSRSVIQKSIEEIKSKIF
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_ORITB
Sequence: MHKLNNVAVLYAKILFKQAIKLNIVSKVKQDLKALKQFCKFLAKQNMSLQLIALMKNKINLMDYLSSTYGLNHLTYNFLKLLQKNNRLTYLSHIIIAFDAQVRNYQGVTLGYLITTKKWSKSAIKEIKDIFERKLNRKLIISNIVDKSIVGGIILRYEDYEYDLSMLGAINRFKSRIKLNY
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: G6PI_CLOB1
Sequence: MKNSLSLDLTKTKPYVEEHELQYLESIIREMDNTLGKKTGSGNKFLGWMDLPINYNKEEFARIKKAAEKIKNTCDVFIVIGIGGSYLGSRAAIEMISNTFYNNLDKNQRKVPQIYFAGNNISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFKELLENKYGKEGAKERIFATTDAAKGALRTLADSEGYETFVIPDDVGGRFSVLTPVGLLPIAASGIDIDEMMKGAADAREEYSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGIFPAAADFSTDLHSMGQYIQEGLRNIFETFINVENPRKSIIVKEDKENLDGLNFLADKDMDYVNHQALRGTVLAHNDGGVPAMVLNVPELSAYYFGQLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYENMKATLEERLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_RHOCS
Sequence: MQRWKLTLEYDGRPFVGWQRQDNGPSVQQALEEAIYRFTQETVTVFCAGRTDAGVHALAMVASVDLAREATADKVQAALNFHLKPHPVAVLRVEPVAPDFHARFSCLGRAYLYRILNRRAPAALEAGRVWHVQGGLDAEAMHEAAQRLVGQHDFSSFRASLCQAKSPVKTLSDLSVARVGEEVRIVARARSFLHHQVRNMVGTLKLVGEGRWTADDVSRALAARNRSAAGPTAPAAGLYFTEAWY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ACCA_CHLL2
Sequence: MAGKVILDFEKPLFELEAKLEEMRVCLRGSAREQDQQDADMLHRDIALLEQKVDALRRSIYKNLTRWQKVQLARHPERPYTLDYIYMMTRDFVELSGDRHFKDDKAIVGGFARLEESASGFSQTVMMIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMKLAEKFRKPVITLIDTPGAFPGIEAEERGQAEAIARNLFEMARLSVPIICVIIGEGASGGAIGIGVGDRVFMAENSWYSVISPESCSSILWRSWNYKEQAAEALKLTADDLLRQGIIDRIVPEPLGGAHTEPEAMAGTLKEMLVEELRDLMSKESDVLVRERVDKFSGMGVWDE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_BORDL
Sequence: MQEGKNIWSLILAAIRKELSEEEFYIWFENLYFIDAIGENIKIATPNSFHKNQVEKRFSKRIKEILIEKGHSTINVEFIHSQNELKDHNTESKDISLKAITHQQDLQTKNKDIKTHAKNIINNTKQYSIKEEIHIKYRNPFLKKKYTFENFIIGTNNKLAYNASLSIAKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHKEFKILYVTAENFLNEFVESIKTNETKRFKKKYRHLDMLLLDDIHDLQKKEGIQEELFHTFNALYEDNKQMVFTCDRQPSELVNFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKAEEDGIKVPKNILNLVAKKVTTNIRDLEAAVTKLKAHIDLEDIEIDTNIVDKIIKEIIAYENDNTNTPNKINIENIKKVILRELKLTNKDIEGNSKKPEITKARHIYAYLLRNFTELSTIEIGKIIGGKTHSTVLYSINKIDKDRNKNLEINNLIIELMNKINKN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A2MG_XYLFA
Sequence: MRDRVAMMLRPLVRGWIPRAVLLLTVAFSFGCNRNHNGQLPQSSGEPVAVAKEPVKGFVLVRAYPDQHDGELALALEFSQPLAATQEFDTLVRLEQDSGNHDGGWSLSDDAKTLRYPYVEADKHYTVLISAGLLAATGSRLGKPRKEPVYTGELDPVVGFASRGSILPARGSRGVPVVSVNVPEVDVEFMRVREKALPAFLARYHKAGQRSSWELSNQGNSRKRLSELADPVYVTRFVLDGKKNERALTYLPIQSIRELREPGLYFAVMKPTGSFSDAFETAFFSVSNIGLHTRAYKDKLFVHTASLRSGNPYKQVDLLVLDAKGETVLQGATDDNGNALLNYTLNAGHVLVSRNGRDISILPFNQPALDLSEFAVAGRENPWFDVFAWSGRDLYRPGETLRISALLRDRDGKPVKPQPVFLRLKQPDGKTFRETRLQPAEQGYLEFTQKIPSDAPTGRWRVEFRTDPASKEAVQGLAVRVEEFLPERMKLELSSAQPVLRAKAPFTLTADAAYLYGAPAAGNRFTANLAVAVEQHPLDNMPGWFFGDATLQLPRGAKETIDITLGADGHLVHDIVLPEEAKPVSPMAVVVSGSVYESGGRPVTRSLKRVLWPADALVGVRPLFDVASGADANGMARFELTRVGVDGKPQSAKGLKATLVRELRDYHWRYSDGRWDYDFTRRFENKETRTVDISTSHTTTLALPVEWGDYRLEVFDPVTGLTMRYPFRAGWSWGDDNRGLDARPDKVKLALDKTSYRAGDTLKVTITPPHPGKGLLLVESDKPLYVQAIDANPSTTLEIPVTADWERHDVYVTALVFRGGSASNNTTPARAVGEVYVPMQRKDRRVAVGLVVPKQMRPAQSLPVTVSVPELAGKQAHVTISAVDAGILNITGFPVPDAAAHFFAQRRLSVDAYDIYGRVIESFEGGTGRLKFGGDMALPPLPQAKRPTARSQTVDLFSGAVKLDAKGNAHIQLPVPDFNGALRVSALVYSDTRYGQRDAETVVRAPILAEASMPRVMAPGDRSTVTVDVQNFTGKQGKFAVKVEGVGPLAVAEAGRSVTLGIDGKTTLNFPLRALEGNSVAQVRVRVEGNGSKAERHYDLPVRAAWPQGLRTQAHVLNVLAPIAFDPALAKGLMPDSVNARLSVSALAPIPFASVLQGVFEYPYGCAEQTASKGYAALWLDDATIKSLGIHGVTPAQRLERLEGALGRLASLQTMNGHFSMCGGNSDVNPVLTPYIAGFLLDAKDAGFAVSDAVLQKALNRLSEDLLSGAHLFYGNDQSEALMFAHQAWSGYVLARVNRAPLGTLRTLYDNERGKAVSGLSLVHLGVALSLQGDRKRGEAAIEAGFAKSEGGRPEVFGDYGSVIRDNALMIALVRAHGLAKPAYEARVMALGRDLEARRRSGWLWLSTQEQVALAQLGRALLVDQKKQVSGTLYVGKQREEIAASRLIGRSFDAAALARGVRFVPQGDVPLYASFEVAGIPRQAPVSDDSQLLVVRRWYTVDGKPWTPGPLKEGQALIVRVSVTSKQNMPDALLTDLLPAGLEIDNFNLGETRQWADVTVDGIALSERANAADIKHEEFRDDRYVAMLQLTGGRTANLFYLVRAVTPGTYKVPPSLVEDMYRPALRGTGRVAPATVTVVQP
What is the function of this protein?
Protects the bacterial cell from host peptidases.
What are the official names of this protein?
Alpha-2-macroglobulin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: YIDC_POLNS
Sequence: MDFKKTIFWAAFSMSGLMLYNNWQVHEGKPSLFGGAPASAPAVADKATTNNKVDVPTQISGAPSVAATPIINGGAIESAEKFTLQNDVLVLEISASGANVIDAKLLKSLTAENKPVELFQYTPTHKYFARSGLVSLNNNDLPNHTSTFKLVQSGKDGSGRPFAVFASERNGVRLEKTFILNPGSYVVDVGHRVTQSTSNPNPLVLYTEIVRDASQEQKIGPFGGAFSANTFTGPVAYTDKEKFNKLEFSAIDKNKITIPTLVAAGEPAWIAMVQHYFASAWIPGDKVARDIYTGRIDNGLYRIGMQTPLGMVGPGSTVVEKAKLFVGPQEERVLETIAPGFELLKDYGYLTILAKPIFWLLDNIHFYVGNWGWSIILLTILIKLVFFPLSAASYKSMARMKEVQPRLVAMKEQYKGEPQKLNQAMMEMYRKEKINPLGGCLPVVIQIPVFISLYWVLLSSVETRGAPWILWIHDLSVPDPYYILPVIMAVSMFVQTKLNPTPPDPIQAKVMMYMPIVFSVMFFFFPAGLVLYWVVNNLLSIAQQWQINQMFGKKPAK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURG_OENOB
Sequence: MRIIVSGGGTGGHIYPALALVESLLKHEPDSKVLYIGSFRGLEGSIVPKTGLDFKQLHVQGFSRSLSLTNFKTVNLFIKAVKKSKHIIHDFKPDIVLGTGGYVSGAVLYAAQRLRIPTVINEQNSIAGVTNKFLSRGADRIAISFPHAANQFPKDKVVLTGNPRGQQVFEKKGDFSLTEFDLDPKLPTVLIFGGSGGALKLNSAVVNFANRFSEQKKFQAIFVTGRKYFDSVSNQLADLKINSSNFVVLPYLDNMDDVLPKIDLLISRSGATTLAEITALGIPSILIPSPNVTANHQEKNARQLEERGAAEVILESDLSSAMLYHDLSELLSHKSKLESMAQAAKKLGHPDAADKLYKLLVQVINERKQETTK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DEF_ECO5E
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: Y3147_YERE8
Sequence: MPSFDIVSEIDMQEVRNAVENATRDLANRWDFRNVPASFELNEKNESIKVASESDFQVEQLLDILRAQLTKRGIEGAALEIPEEMDRSGKTYSVEAKLKQGIESVQAKKLVKLIKDSKLKVQAQIQGEQVRVTGKARDDLQSVMALIRGADLGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein YE3147.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: CTU1_CRYNJ
Sequence: MPPTPCSLCHTARALVKRPKTGQQVCKDCFFEVFETEVHNTIVEGEGIFKRGERVAIGASGGKDSTVLAHVLSVLNKRYDYGLDLYLLSIDEGITGYRDDSLETVKQNQAEYGLPLKILSYSELYGWTMDKIVEQVGKKNNCTFCGVFRRQALDRGAAQLGVDHIVTGHNADDIAETVLMNIMRGDIARLARCTAVTTQSEDTIKRSKPFKYAYEKEIVMYAYFKKLTYFSTECIYSPDAYRGHARVFLKDLEAVRPSAIVDIIHSGESFVLEQSVQRGMKALQTCLRCGYISSNDLCKACALLEGLESGLSRSALRQTQESTSAAPEGHRTIPMFERYASLNGTPRTPPTPAEPVEGIERAA
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5NTD_VIBVU
Sequence: MKQRLIVKTALSAAILATLAGCATQPTQEWAADTTYKLTVLHTNDHHGRFWQNKYGEYGMAARKTLIDELRAEIQAEGGSVLLLSGGDINTGVPESDLQDAEPDFKGMSKIGYDAMALGNHEFDNPLDVLMKQKEWANFPMLSANIYDKKTGERMFQAYEMFDKQGIKIAVIGLTTEDTAKLGNPEFIGAIDFRDPKEEAKKLIAELKETEKPDLIFAVTHMGHYEDGKRGINAPGDVALARYLNEGDLDMIVGGHSQEPVCMEAPNVVKKNFKPADECKPDQQNGTYIVQAHEWGKYVGRADYEFRNGELRMVSYDLIPVNLKKKVEVDGKSQRVFIESEIKEDTALLEFLRPYQEKGQEQLNVKIADTNGKLEGDRNVVRFQQTNLGRLIAVSHMERAKADFAVMNSGGVRDSIEAGEVTYKDVLTVQPFANILTYTDMTGKEVLDYLNVVATKPVDSGAYAQFAGISMTVANGKVSNVFIGGKQLRLDETYRFTVPSYNAAGGDGYPKLTGHPGYVNTGFVDAEVLKEFLEKNSPIDVNKFAPNGEIVYK
What is the function of this protein?
Degradation of extracellular 5'-nucleotides for nutritional needs.
What are the official names of this protein?
5'-nucleotidase.
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ATPA_RHOPB
Sequence: MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLETDNVGIVIFGADREIKEGQTVKRTRAIVDTPVGKGLLGRVVDALGNPIDGKGPIQSTERKRVDVKAPGIIPRKSVNEPMATGLKAIDALIPVGRGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPEGQKLYCVYVAIGQKRSTVAQFVKVLEEQGALEYSIVVAATASDPAPMQYIAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNEDHGSGSLTALPIIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDASTQRLLNRGSRLTELLKQPQFSPLKMEEQVVVIYAGVNGYLDPLPVSKVRAFEDGLLSLLRGKNVEILNTIRDSRDLSNETAAQLKSVVEGYAKTFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NAR21_ORYSJ
Sequence: MARLAGVAALSLVLVLLGAGVPRPAAAAAAKTQVFLSKLPKALVVGVSPKHGEVVHAGENTVTVTWSLNTSEPAGADAAFKSVKVKLCYAPASRTDRGWRKASDDLHKDKACQFKVTVQPYAAGAGRFDYVVARDIPTASYFVRAYAVDASGTEVAYGQSSPDAAFDVAGITGIHASLKVAAGVFSTFSIAALAFFFVVEKRKKDK
What is the function of this protein?
Acts as a dual component transporter with NTR2. 1, NRT2. 2 and NRT2. 3.  Required for high-affinity nitrate transport.  Involved in the regulation of NRT2. 1, NRT2. 2 and NRT2. 3 expression, and in both, HATS (high-affinity transport system) and LATS (low-affinity transport system) activities in plant roots.  Imports nitrate with high affinity when expressed with NTR2. 1, NTR2. 2 or NTR2. 3 in a heterologous system (Xenopus oocytes).
What are the official names of this protein?
High-affinity nitrate transporter-activating protein 2.1, OsNAR2.1.
What is the protein family that this protein belongs to?
Belongs to the NAR2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ATPB_STAAB
Sequence: MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIAMDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAPAFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEHYEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQKGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CSN8_XENLA
Sequence: MKLSESVMAQNSVSFQKLQEQCEEQELEAPGGIASPQVYNQLLALYLLHNDLNNARYLWKRIPSAIKSSHSELGGIWEVGQKIWQRDFPGIYTSISAYQWSENIQQIMEAVRDATQQRAFGLVSQAYTSISADDFAAFVGLPVEEAVKGVLEQGWQADSATGMVMPKKPDSAPLSLIPNEQQLARLTDYVAFLEN
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 8, Signalosome subunit 8.
What is the protein family that this protein belongs to?
Belongs to the CSN8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL3_MYCBP
Sequence: MARKGILGTKLGMTQVFDESNRVVPVTVVKAGPNVVTRIRTPERDGYSAVQLAYGEISPRKVNKPLTGQYTAAGVNPRRYLAELRLDDSDAATEYQVGQELTAEIFADGSYVDVTGTSKGKGFAGTMKRHGFRGQGASHGAQAVHRRPGSIGGCATPARVFKGTRMAGRMGNDRVTVLNLLVHKVDAENGVLLIKGAVPGRTGGLVMVRSAIKRGEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.