PharMolix/UniProtQA huggingface dataset:
Protein: DREB_RAT
Sequence: MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQSLEAEEAKRRLKDQSIFGDQRDEEEESQMKKSESEVEEAAAIIAQRPDNPREFFRQQERVASASGGSCDAPSPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPTRSPSDSSTASTPITEQIERALDEVTSSQPPPPPPPPPPAQEAQESAPRLDGEEVCKEAKVAAAPQVWAGCAEEPPRAQEPPLLQSSPTEDLMCTESPEQAVLAASPEPDASVTSVADAHAADTIETTTATTATTIADNVTPAAASLIDLWPGNGEEASTPQAEPRVPTPPSGAEASLAEVPLLNEAAQEPLPPVGEGCANLLNFDELPEPPATFCDPEEEAEGEPLAASQVLTMPSALEEVDQVLEQELEPEPHLLTNGETTQKEGTQQASEGYFSQSQEEEFAQSEEPCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD
What is the function of this protein?
Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (By similarity).  Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (By similarity).  Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity).  Involved in memory-related synaptic plasticity in the hippocampus (By similarity).
What are the official names of this protein?
Drebrin, Developmentally-regulated brain protein.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cytoplasm, cell cortex. Cell junction. Cell projection. Cell projection, growth cone. Note=In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC). Colocalized with RUFY3 and F-actin at the transitional domain of the axonal growth cone.
Protein: Y1430_BRUA2
Sequence: MAQGDDNKQAIGQIIRQEQALIFPSLDENDAFSLGQRIRDIAVKDKLGIAIDISLWDRRLFFAATAGATADNTEWLRRKFNVVRRFHVSTYRLVLEQNREDRMFAPYKALDVADYALAGGGFPIRVSGAGVIGAVIVSGLPQREDHNLVVRAVAEHVGQDPVALALPAA
What are the official names of this protein?
UPF0303 protein BAB1_1430.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: C81F4_ARATH
Sequence: MFNYVIILPLALFLLAYKFFFTSKKQRYYLPPSPSYSLPILGHHLLIKPPVHRLFHRLSNIHGPIFYLRLGSRRAVVISSSSLARECFTGQNDVIVSNRPRFLTSKYIAYNYTTIATTSYGDHWRNLRRICSLEIVSSKRLANFLHIRKEEIQRMLTRLSRDARVGKEVELESILYDLTFNNIVRMVTGKIYYGDDVSDKEEAELFKKLFTFITTNSGARHPGEYLPFMKIFGGSFEKEVKAAAKVIDEMLQRLLDECKSDKDGNTMVNHLLSLQQDDPEYYTDIIIKGLMLGIMVASSETSALTIEWAMASLLNHPKVLDKVKLEIDEIIGQDRLIEESDIANLPYLQNVVSETLRLHPAAPVLVPRSTAEDIKIGGYDVPRDTMVMVNAWAIHRDPDLWTEPERFNPERFNGGEGEKDDVRMLIAFGSGRRICPGVGLAHKIVTLALGSLIQCFDWKKVNEKEIDMSEGPGMAMRMMVPLRALCKTRPIMNKLPAYTKV
What is the function of this protein?
Involved in indole glucosinolate biosynthesis.  Catalyzes hydroxylation reactions of the glucosinolate indole ring.  Converts indol-3-yl-methylglucosinolate (I3M) to 1-hydroxy-indol-3-yl-methylglucosinolate (1OH-I3M) intermediate.  This hydroxy intermediates is converted to 1-methoxy-indol-3-yl-methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2).
What are the official names of this protein?
Cytochrome P450 81F4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RBD2_DEBHA
Sequence: MSSPSFINKLALPNLATITQYPALTVGLSVFTFLLLVIDLCSNQALSQKFSLYPNAPFEFDLNRLSFYLLFHRGFTHWLLNVVGLFSPLAIFERTNGTVFTGVTLNVLAVTAGLQFCIVGKLLYPNTQVIGLSGVVFSFMSFMAYKEHHTTPVIYTFKYQGSEVSIPTLYSPFIFLIVCMVLIPGSSFWGHLAGISSGYLLALGYIKFLYPPSKAILFIERKLQTPINALRSLVVYYKEEEAIEQRGVSYNPLLSSDPESALNDIPVTTGARTNSFAGEGQVLGAT
What is the function of this protein?
Probable serine protease.
What are the official names of this protein?
Rhomboid protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Protein: S22A6_PIG
Sequence: MAFNDLLLQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPAHHCRPPADTNLSRDTELEAWLPRDGQGRPASCLRFTSPQRGPPFPNGTGTNGTGTTEPCTNGWIYDPGTFPSTIVTEWDLVCSRRALRQLAQSLYMVGVLLGAMIFGYLANRLGRRKVLILNYLQTAVSGTCAAFAPNFPVYCAFRLLSGMSLAGISLSCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPRWRHLQMLVSVPFFAFFIYSWFFIESARWYSSSGRLDLTLKALQRVAWINGKREEGASLSMEVLRASLNKELTMDKGQASAMELLRCPVLRRLFLCLSLLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINTMGRRPAQMASLLLAGICILINGVVPQDQSIVRTALAVLGKGCLAASFNCIFLYTGELYPTMIRQTGLGMGSTLARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAATALLPETLGQPLPDTVQDVESRRKRQRRRQKQQQEQQKQMVPLQASA
What is the function of this protein?
Involved in the renal elimination of endogenous and exogenous organic anions.  Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc).  Mediates the transport of prostaglandin E2 (PGE2) and prostaglandin F2-alpha (PGF2-alpha) and may be involved in their renal excretion (By similarity).  May contribute to the transport of organic compounds in testes across the blood-testis-barrier (By similarity).  Also mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) and edaravone sulfate.  Mediates the sodium-independent uptake of p-aminohippurate (PAH).  PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), indomethacin, sulindac, diclofenac, carprofen, okadaic acid, benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, bumetamide, losartan, probenecid, phenol red, urate, glutarate and alpha-ketoglutarate (By similarity).  PAH uptake is inhibited by probenecid and alpha-ketoglutarate.
What are the official names of this protein?
Solute carrier family 22 member 6, Organic anion transporter 1, Renal organic anion transporter 1, ROAT1, pOAT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUC_PSEA8
Sequence: MAGKTLYDKLWDMHLVKQRDDGSALIYIDRHILHEVTSPQAFEGLRLAGRKPWRIDANIATPDHNVPTTRTERKGGIAAIADEVSRLQVQTLDENCDDFGITEFKMNDVRQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVAKKMKNMLVKVEGRLPAGVTAKDIVLAVIGRIGTAGGNGHAIEFAGSAIRDLSIEGRMTICNMSIEAGARVGLVAVDQKTIDYVKGRPFAPSAEQWDQAVACWQGLVSDADARFDTVVELDAAQIKPQVSWGTSPEMVLAVDQNVPDPARESDPIKRGSIERALKYMGLRPNQAITDIQLDRVFIGSCTNSRIEDLRAAAEVARGRKVAATIKQALVVPGSGLVKEQAEKEGLDRIFIEAGFEWREPGCSMCLAMNPDRLESGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVNGRFIDVRELLA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MURA_ECO8A
Sequence: MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPAR2_HUMAN
Sequence: MGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
What is the function of this protein?
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.  Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins.  Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway.  Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.
What are the official names of this protein?
Lysophosphatidic acid receptor 2, LPA receptor 2, LPA-2, Lysophosphatidic acid receptor Edg-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell surface. Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA colocalizes with RALA in the endocytic vesicles.
Protein: HXD9_HUMAN
Sequence: MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D9, Homeobox protein Hox-4C, Homeobox protein Hox-5.2.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPO3B_MYCBO
Sequence: MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVGVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAP2_PSEAE
Sequence: MDAVTVNNFFLIGAVLVGMSILVSSLSSRLGIPILVIFLAVGMIAGNDGVGGIVFDNYPMAYLVGNLALAVILLDGGLRTRVSSFRVALWPALSLATLGVLVTTGLTGIAAAWLFDLHWMEGLLIGAIVGSTDAAAVFSLLGGKGLNERVTATLEIESGSNDPMAVFLTVTLIEMLASGQTGLSWGFALHLVQQFGLGALLGLGGGWLLLQLINRMHLAGGLYPLLVISGGLLVFALANAVGGSGILAIYLCGLLLGNRPIRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLWPIALPALALALWMILVARPLSVLIGLIPFRAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNAQLFFNVAFFIVLVSLLVQGTSLPWAARLLRVVVPPDPAPISRAGLEIHPTSEWELFVYHLNKEKWCIGAALRELKMPGGTRIAALFRGTELLHPSGSTILEADDILCVIGHEHDLPALGKLFSQAPDRGLGARFFGDFVLEGDAQLSAVASLYGLKLDGIDGEQALGRFIAHEIGGEAVIGDQVEWNGLTWTVAALEGNRIRKVGVKFPEGRPGPGLFL
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UL10_HCMVA
Sequence: MRRLINHIVNHDLFRWSVMTAMIFYRYSETCMEVTVRVGDPVTLGSGHGYHPGQKVHWYNQSCVGISNGENTHPICTYDPPKPGRRKTMKTTPLPSPLLYECHNSTLSILHVNVSDPKNYCRRKCPPNGNCEFPTCFTLSLISRTTTTRKPGQKTTLSRLKTTPNKHTQHKRSTRRTSPRDYNVTGLPKGFADSFTGNVEAHRAKDAAHSAWILIVIIIIIVVILFFFKIPQRLREKWDTRGYLYKGTDGLPTTDYLS
What are the official names of this protein?
Uncharacterized protein UL10.
What is the protein family that this protein belongs to?
Belongs to the RL11 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IPYR1_PSESM
Sequence: MSYSKIPAGKDLPNDIYVAIEIPANHAPIKYEIDKDTDCLFVDRFMATPMFYPANYGFIPNTLADDGDPLDVLVVTPYPVTPGSVIRARPVGILHMTDDGGGDAKVIAVPHDKLSQLYVDVKEYTDLPALLLEQIKHFFENYKDLEKGKWVKIEGWGNADAARAEIMKSVEAFKG
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase 1, Pyrophosphate phospho-hydrolase 1, PPase 1.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPC_PSEAB
Sequence: MNAMHNAPASDPSLVYPSPLKEFWQSFAHNKGALGGLLFMLLIVFCALFAPWVAPYDPSEQFRDFLLTPPSWLEGGQARFLLGTDELGRDLLSRLIHGARLSLLIGLSSVVISLIPGILLGLLAGFSPNRAGPLIMRLMDIMLALPSLLLAVAIVAILGPGLINTVIAIAIVSLPAYVRLTRAAVMTELNRDYVTASRLAGAGTLRLMFVCVLPNCMAPLIVQATLSFSSAILDAAALGFLGLGVQPPTPEWGTMLASARDYIERAWWVVSLPGLTILLSVLAINLMGDGLRDALDPKLKNAA
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in the uptake of various di/tripeptides (PubMed:25338022).  Is also involved in the uptake of phaseolotoxin, a toxic tripeptide inhibiting the enzyme ornithine carbamoyltransferase (PubMed:25338022).  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Di/tripeptide transport system permease protein DppC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TX31C_SCOMU
Sequence: MKSWMAILLVMALIIFTLDNCYSTDDKPIGKCGDRQRNKLCLVCQDRSQIDYYYTECCIYDQTYYMCLDMLRH
What is the function of this protein?
Inhibits voltage-gated potassium channels.
What are the official names of this protein?
Kappa-scoloptoxin(03)-Ssm1c, Kappa-SLPTX(03)-Ssm1c, Kappa-scoloptoxin-Ssm1c, Kappa-SLPTX-Ssm1c.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAC_PSEAE
Sequence: MLTHLDSQGRANMVDVTEKAVTSREATAEAVVRMRPETLQLIQDGGHPKGDVFAVARIAGIQAAKRTHELIPLCHPLLLTSVKLELQAEAPDAVRIRARCRLAGQTGVEMEALTAASVAALTIYDMCKAVDRGMVIEQVQLLEKLGGKSGHYRKEEEGQA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PDH1_CANGA
Sequence: MNTPDDSSVSSVDSHQPYMGFDDNVEKRIRELARSLTQQSLTSSNRSVNKEAPADGSAPLDRVSTRASSIFSADFKGVNPVFSDEEEDDYDARLDPNSDEFSSKAWVQNMAKITTGDPEFYKPYSIGCCWKDLSASGESADVSYQSTFLNLPVKLLNAVWRKARPARESDTFRILKPMDGLLKPGELLVVLGRPGSGCTTLLKSISSTTHGFQISKDSVISYNGLTPNEIKKHYRGEVVYNAEADIHLPHLTVYQTLVTVARLKTPQNRVKGVTREDFANHVTDVAMATYGLSHTRDTKVGNDLVRGVSGGERKRVSIAEVWICGSKFQCWDNATRGLDSATALEFVRALKTQAHIAKNVATVAIYQCSQDAYNLFNKVSVLYEGYQIYFGDAQHAKVYFQKMGYFCPKRQTIPDFLTSITSPAERRINKEYLDKGIKVPQTPLDMVEYWHNSEEYKQLREEIDETLAHQSEDDKEEIKEAHIAKQSKRARPSSPYVVSYMMQVKYILIRNFWRIKNSASVTLFQVFGNSAMAFILGSMFYKIQKGSSADTFYFRGAAMFFAILFNAFSSLLEIFSLYEARPITEKHRTYSLYHPSADAFASVISEIPPKIVTAILFNIIFYFLVNFRRDAGRFFFYFLINVIAVFAMSHLFRCVGSLTKTLQEAMVPASMLLLALSMYTGFAIPRTKMLGWSKWIWYINPLAYLFESLMVNEFHDRRFPCNTYIPRGGAYNDVTGTERVCASVGARPGNDYVLGDDFLKESYDYENKHKWRGFGVGMAYVIFFFFVYLILCEFNEGAKQKGEMLVFPHSVVKRMKKEGKIRDKTKMHTDKNDIENNSESITSNATNEKNMLQDTYDENADSESITSGSRGGSPQVGLSKSEAIFHWQNLCYDVPIKTEVRRILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERTTMGVITGDVMVNGRPRDTSFSRSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNEYVEAVIKILEMETYADAVVGVPGEGLNVEQRKRLTIGVELAAKPKLLVFLDEPTSGLDSQTAWATCQLMKKLANHGQAILCTIHQPSAMLMQEFDRLLFLQKGGQTVYFGDLGKGCKTMIKYFEDHGAHKCPPDANPAEWMLEVVGAAPGSHANQDYHEVWRNSEQFKQVKQELEQMEKELSQKELDNDEDANKEFATSLWYQFQLVCVRLFQQYWRTPDYLWSKYILTIFNQLFIGFTFFKADHTLQGLQNQMLSIFMYTVIFNPLLQQYLPTFVQQRDLYEARERPSRTFSWKAFILAQIVVEVPWNIVAGTLAYCIYYYSVGFYANASQAHQLHERGALFWLFSIAFYVYVGSLGLFVISFNEVAETAAHIGSLMFTMALSFCGVMATPDAMPRFWIFMYRVSPLTYLIDALLSTGVANVDIRCSNTELVTFTPPQGLTCGQYMTPYLNVAGTGYLTDPSATDECHFCQFSYTNDFLATVSSKYYRRWRNYGIFICFIVFDYVAGIFLYWLARVPKTNGKIAKNGKTAKVNFIRRLIPF
What is the function of this protein?
Pleiotropic ABC efflux transporter that confers resistance to structurally and functionally unrelated compounds including caspofungin or azoles such as fluconazole, itraconazole, posaconazole, voriconazole, and isavuconazole (PubMed:11257032, PubMed:12244114, PubMed:12557277, PubMed:15105134, PubMed:15388433, PubMed:16803598, PubMed:17581937, PubMed:20038613, PubMed:24273749, PubMed:24838041, PubMed:26482310, PubMed:27486188, PubMed:29371812).  Does not play a role in the azole resistance in mature biofilms (PubMed:18651314).
What are the official names of this protein?
Pleiotropic ABC efflux transporter of multiple drugs PDH1, P leiomorphic drug resistance homolog 1, Pleiotropic drug resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EX7S_CHLT2
Sequence: MTKKAKNVEKVPFEDAMKRLEEIIDLMNQPTTSLEASLALYEEADQLMRICESRIQEVEARIKQLSDQRSES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPER1_ARATH
Sequence: MGSTFFGRPNVVGSSPPSSSPTSSSSSPATRRGKKNGSEKPKQPQRGLGVAQLEKIRLHGEMSCNSFNSYNPSLYPQEDVRMQGGYSSIPSQSSAPYGFYPNMMMGVHRDQYDRATMSWNPSYGILESQHSLEPNITRHFLNEDPSSTTRRSKSLGSGIQHSGSSENQEVDLELRLSL
What is the function of this protein?
Adapter-like transcriptional repressor recruiting TPL/TPR corepressors to inhibit TCP transcription factors.
What are the official names of this protein?
Protein SPEAR1, SPL-like, EAR-containing protein 1, TCP interactor containing EAR motif protein 2.
Protein: ISPE_PSE14
Sequence: MTALQDMAKAQLVLPAPAKLNLMLHILGRRPDGYHELQTLFQFLDYGDELGFTVREDGEIRLQTDVPGVPHDSNLIVKAARALQKQSGCTLGMDIWLEKRLPMGGGIGGGSSDAATTLLALNHLWQLGWDEDRLAQLGLTLGADVPVFVRGHAAFAEGVGEILTPVDPEEPWYLVLVPQVAVSTAEIFSDPLLTRDTPPIKVRPVPKGNSRNDCKAVVERRYPEVRNALNLLGNFTEAKLTGTGSCVFGAFPNKAEADKVSALLTETLTGFVAKGSNISMLHRKLQIL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: IF11_BURVG
Sequence: MAKDDVIQMQGEVIENLPNATFRVKLENGHVVLGHISGKMRMHYIRILPGDKVTVELTPYDLSRARIVFRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_TRIV2
Sequence: MKFSDIISKLEVTNYSLTQNPNNDPEITGMAAIDEATSGTLSYIEGAKFASFIAKTNASALILPQNEAMQAQAQERGIVWMATPEPRLLFAKAIALFYQPYTPTPEIHPTAVIHPTAKIGNDVYIGPHVVIQPGVEIGNGVIIHPNVVIYPGVKIGDRTILHANCTIEERSQIGADCVIHSGAVIGGEGFGFVPTRTGWYKMEQSGYVVLEDRVDIGCNTTIDRPSVGETRVGYDTKIDNLVQIAHGCQIGAGCAIAAQTGMAGGVKLGNRVILAGQVGIANQAKMGDGSTASAQTGILHDVKPGEVVSGTPAIPHKMYLKIAALYSRLPDMYQAFRQSQRQLEEEGKR
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: MNMG_HYPNA
Sequence: MPDFPDFDVIVIGGGHAGCEAAAASARFGARTALITHKRSTIGEMSCNPAIGGLGKGHLVREIDALDGVMGRLADKAGIQFRMLNRSKGPAVWGPRSQIDRKLYREAMQSELADYPNLTIIEDGAEDLIVEDGLIRGVVGLTGQRYGASKVVITTGTFLKGEIHIGAKRIPAGRIGEAPALGLSDRLYSIGLPMGRLKTGTPARLDGRTIHWDRLEMQPADEQPIPFSFLNSEITVRQVQCGITWTTPETHAIIEAHMNESAVYSGAISGRGPRYCPSIEDKVNRFGDRDRHQVFLEPEGLDDHTVYPNGISTSLPEEVQEKFIRTIPGLEDAVILQHAYAIEYDYVDPRALSPALEVKLMPGLYLAGQINGTTGYEEAGAQGLMAGLNAARAASGKDPVIFDRAEAYIGVLIDDLVTRGVTEPYRMFTSRAEYRLALRADNADQRLTQRGIDAGVVCETRAAMFHVKHRALESARNLLKTLNLSPAAAVRNGWAVNQDGRIRSAWEYLSYKEICFDHLAQVWPELSAIPAEIVAQIEIEALYSAYLDRQAEDVAALRRDEALSIPSDLDYDLIGGLSNEVRQKLKSVRPGTLGQAGRIEGVTPGALTALLGHVRRVRKAG
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.