PharMolix/UniProtQA huggingface dataset:
Protein: PP276_ARATH
Sequence: MRKALCLTESLSAIAENSTTLLNLNRRLTGLTRSGENRNALKLFADVHRCTTLRPDQYSVSLAITTARHLRDTIFGGQVHCYAIRSGLLCHSHVSNTLLSLYERLGNLASLKKKFDEIDEPDVYSWTTLLSASFKLGDIEYAFEVFDKMPERDDVAIWNAMITGCKESGYHETSVELFREMHKLGVRHDKFGFATILSMCDYGSLDFGKQVHSLVIKAGFFIASSVVNALITMYFNCQVVVDACLVFEETDVAVRDQVTFNVVIDGLAGFKRDESLLVFRKMLEASLRPTDLTFVSVMGSCSCAAMGHQVHGLAIKTGYEKYTLVSNATMTMYSSFEDFGAAHKVFESLEEKDLVTWNTMISSYNQAKLGKSAMSVYKRMHIIGVKPDEFTFGSLLATSLDLDVLEMVQACIIKFGLSSKIEISNALISAYSKNGQIEKADLLFERSLRKNLISWNAIISGFYHNGFPFEGLERFSCLLESEVRILPDAYTLSTLLSICVSTSSLMLGSQTHAYVLRHGQFKETLIGNALINMYSQCGTIQNSLEVFNQMSEKDVVSWNSLISAYSRHGEGENAVNTYKTMQDEGKVIPDAATFSAVLSACSHAGLVEEGLEIFNSMVEFHGVIRNVDHFSCLVDLLGRAGHLDEAESLVKISEKTIGSRVDVWWALFSACAAHGDLKLGKMVAKLLMEKEKDDPSVYVQLSNIYAGAGMWKEAEETRRAINMIGAMKQRGCSWMRL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g49740.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: IGF1R_XENLA
Sequence: MKAELVPVCTAWILGLLLCLGPAAAKVCGPNMDIRNDVSELKQLRDCVVIEGYLQILLISNAKAEDFRNLRFPNLTVITDYLLLFRVSGLVSLSNLFPNLTVIRGRVLFYNYALVIFEMTDLKEIGLYNLRNITRGAVRIEKNSELCYVSTVDWSLVLDAVYNNYIVGNKPPKECVDLCPGAREKMQICEKSSINNEFADRCWSDEHCQKVCPSVCGKRACSDNNECCHPECLGSCTAPDNDTACVACHHYFYEGRCVPTCPSNTYKFEGWRCITREVCAKMHIWIHSTIPFIIHKGECVYECPSGYMLNKSQSMTCSPCEGPCPKICEEKMKTIDSVTSAQMLEGCTVLKGNLQLNIRKGQNIAAELENFLGLIETVTGYVKIRHSHALVSLSFLKSLRYILGEEQMPGNYSFYVFDNNNLQQLWDWSKHNLTIKEGKIRFAFNSKLCASEIYRMEEVTGTKGRQAEEDISLSTNGNMASCESHVLNFTSRSKIKNRIKLTWERYRPPDYRDLISFTVYYKEAPFRNVTEYDGQDACGSNSWNMVDVDLPASKESDPGILLQGLKPWTQYAIYVKAITLTMLENRHIHGAKSKIIYMRTDAAVPSIPQDMISASNSSSQLVVKWNPPSLPNGNLSYYIVRWQQQPQDRHLYQYNYCFKDKVPNRKYANGTIDTEGGTEPTKPEGSVGEKGHYCACPKTEAEEKAEKDEAEYRKVFENFLHNSIFVPRPNRRRRDVLAVGNSTVTSYEKNSTTEDFSNFSDSERDDIEYPFYETKVDYKWERTVISNLQPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAAGADDIPGIVNTKEEDDGVIFLGWPEPLRPNGLILMYEIEYKHQGEVHRECVSRQDYRKNGGIKLVRLPPGNYSAQVQAISLYGNGSWTEMVSFCVKLKPDVRNNILQMVVAIPLALSFLLVGIISIVCFVFKKRNSNRLGNGVLYASVNPEYFSAAEMYVPDKWEVPREKITMNRELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIISSIKDELDPGFKEVSFFYSEENKPPDTEELDLEAENMESIPLDPSCALQNSEHHAGHKSENGPGVVVLRASFDERQPYAHMNGGRKNERALPLPQSSAC
What is the function of this protein?
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity.  It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade.  Plays a role in oocyte maturation.  Promotes head development by inhibiting Wnt signaling during embryogenesis.
What are the official names of this protein?
Insulin-like growth factor 1 receptor, xIGF-1R, xIGFR.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Expressed at the oocyte surface.
Protein: PYRG_CLOB8
Sequence: MSTKYVFVTGGVVSALGKGITAASLGRLLKNRGVKISIQKFDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDESLTQNSNVTTGKIYSSVIEKERRGEYLGGTVQVIPHITNAIKDKVYQVAKDRDVDVVITEIGGTVGDIESQPFLESIRQIKSEVGAENVCYIHVTLVPYLGKAGELKTKPTQHSVKELRMIGIQPDIIVCRTEKELSDDVKAKIGLFCNIDGRSVIQNLDAENLYEVPLMLHSEGLDNLVCEKLHLGCKDIDNSEWIQMVQKIKNLKNNVKIALVGKYVELHDAYISVVEALSHGGYANNTNVEIKWINAENIENSNAQELLKDVDGILVPGGFGDRGIEGKIAAIKWARENKKPFLGICLGMQCAVIEYARSVLGYEDANSSEINPGTNYPVIDLMPDQKDIENLGGTMRLGLYPCRLAENTNSYEVYKNEIINERHRHRYEFNNEFRKQITEAGMKIAGTSPDERLVEIVEVEDHPWYVAVQFHPELKSRPNKPHKLFVGFIKAALEENKSK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SDHE_YERPE
Sequence: MEIDNKARIHWACRRGMRELDISIMPFFEYEYDSLSDNEKQAFIRLLECDDPDLFNWLMNHGEPQDSELYQMVKLIQSRNKARGPVAM
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLN1B_STRVR
Sequence: MFQNADEAKKLIADEDVKFIDVRFCDLPGVMQHFTIPASAFDPAEELAFDGSSIRGFQAIHESDMAVRADLSTARVDPFRRDKTVNINFFIHDPITGEQYSRDPRNVAKKAEAYLASTGIGDTGYFGPEAEFYVFDSVRLANSATESFYHIDSEAGAWNTGALENNRGYKVRYKGGYFPVPPVDHFADLRAQISLELDRAGLQVERHDHEVGTAGQAEINYKFNTLLAAADDLQLFKYIVKNVAWQNGKTATFMPKPIFGDNGSGMHVHQSLWTGGQALFYDEAGYAGLSDTARYYMGGILKHAPSLLAFTNPTVNSYHRLVPGFEAPVNLVYSQRNRSAAMRIPITGSNPKAKRVEFRAPDSSGNPYLAFSALLLAGLDGIKNKIEPAEPIDKDLYELAPEEHAGVPQVPTSLPAVLDRLEADHEFLLAGDVFTPDLIETWIDYKRTNEIAPLQLRPHPYEYEQYYDV
What is the function of this protein?
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHYS_SACS2
Sequence: MINREDLLKNPVEDITLSDLKKYNDIVSVFDKIYGFSSEGIVNGSKILKEMIKNADLRFLSFTANLVSTGLRGLFADLIKKGYFNIVVTTGGTIDHDLARSFGGVYYKGSFDIDDTMLKDLEIHRLGNVLVPFESYGKVIEDVVRKFLPEITKDRKEISAYELLWEFGKRITDSNSILRAAYDKNVPIIVPGILDGSFGTNLFIQSQFLNFRINLFEDMRLIKDLIFSSKKSGALIIGGGISKHHTIWWNQFKDGLNYAIYITTAQEYDGSLSGAKPREAISWNKIRPDAKHVTIYGDATIIVPILAASLLS
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: CPS1_ISOER
Sequence: MLQSMGDGEISISPYDTAWVALVEDDGGGRRQPQFPSSLEWISSNQLADGSWGDAGTFSIFDRILNTLACVVALRSWNIHPHKTDKGIWFMKKNMCRIDEENLEHMPIGFEVALPSLIDIAKKLEIDIPTQTRGLQEIYARREIKLKKIPRDIMHQVPTTLLHSLEGMAGLKWEKLLKLQSQDGSFLFSPSSTAFALQQTRDHGCLKYLTNHIHKFNGGVPNVYPVDLFEHLWAVDRLQRLGLSRYFQPEIEECIAYVHRQWTEKGICWARNSQVEDIDDTAMGFRLLRLHGYEVSADVFRHFKSDGGEFFCFKGQSTQAVTGMYNLYRASQLMFPGENILVDAARFSANFLQLKRANNDLLDKWIITKDLPGEVGYALDVPWYASLPRVETRFYLDQYGGDDDVWIGKTLYRMPYVNNNKYLELAKLDYNNCQALHQQEWQNIQKWYRSCSLGEFGMTERSLLQTYYVAAASVFEPEKSQERLAWAKTAILMETISSHFEFQQLSRDQKRAFITEFEHDSILKYTNGGRYKRRSSLVGTLVRTLNHLSLDILLAHGRDIHQPLKNAWCKWLNSWEEGGDAELLLRTLNLMSGGGRRRRWASEELLSSNPKHEQLLKATIGVCDKLRLFQRRKVQGGNGCMNATGITTVEIESEMRELVKLVVTRSSSEDLDSEIKQNFLTIARSFYYAAYCNQGTINFHIAKVLFEKVL
What is the function of this protein?
Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities, and in the production of gibberellins phytohormones (PubMed:22284743).  Catalyzes the conversion of (2E,6E,10E)-geranylgeranyl diphosphate (GGPP) to ent-copalyl diphosphate (ent-CPP) (PubMed:22284743).
What are the official names of this protein?
Ent-copalyl diphosphate synthase 1, IeCPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsc subfamily.
Protein: TNPF_STAAU
Sequence: MNKQVRNTTEIVRLAKLKSQKTREKVDKAISKFCIEGFAINFNSIAKERNVSKSWLYKEHDIRQRIESLRERQITSNVVSKPKKSSRSEEILIKTLKRRVMELEKENKKLQNQIQKLYGDLYNKE
What are the official names of this protein?
Transposase C from transposon PsiTn554.
Protein: ZC12C_HUMAN
Sequence: MPGGGSQEYGVLCIQEYRKNSKVESSTRNNFMGLKDHLGHDLGHLYVESTDPQLSPAVPWSTVENPSMDTVNVGKDEKEASEENASSGDSEENTNSDHESEQLGSISVEPGLITKTHRQLCRSPCLEPHILKRNEILQDFKPEESQTTSKEAKKPPDVVREYQTKLEFALKLGYSEEQVQLVLNKLGTDALINDILGELVKLGNKSEADQTVSTINTITRETSSLESQRSESPMQEIVTDDGENLRPIVIDGSNVAMSHGNKEVFSCRGIKLAVDWFLERGHKDITVFVPAWRKEQSRPDALITDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFESDGIIVSNDNYRDLANEKPEWKKFIDERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPIVPEHKKQPCPYGKKCTYGHKCKYYHPERGSQPQRSVADELRAMSRNTAAKTANEGGLVKSNSVPCSTKADSTSDVKRGAPKRQSDPSIRTQVYQDLEEKLPTKNKLETRSVPSLVSIPATSTAKPQSTTSLSNGLPSGVHFPPQDQRPQGQYPSMMMATKNHGTPMPYEQYPKCDSPVDIGYYSMLNAYSNLSLSGPRSPERRFSLDTDYRISSVASDCSSEGSMSCGSSDSYVGYNDRSYVSSPDPQLEENLKCQHMHPHSRLNPQPFLQNFHDPLTRGQSYSHEEPKFHHKPPLPHLALHLPHSAVGARSSCPGDYPSPPSSAHSKAPHLGRSLVATRIDSISDSRLYDSSPSRQRKPYSRQEGLGSWERPGYGIDAYGYRQTYSLPDNSTQPCYEQFTFQSLPEQQEPAWRIPYCGMPQDPPRYQDNREKIYINLCNIFPPDLVRIVMKRNPHMTDAQQLAAAILVEKSQLGY
What is the function of this protein?
May function as RNase and regulate the levels of target RNA species.
What are the official names of this protein?
Probable ribonuclease ZC3H12C, MCP-induced protein 3, Zinc finger CCCH domain-containing protein 12C.
What is the protein family that this protein belongs to?
Belongs to the ZC3H12 family.
Protein: NXF3_HUMAN
Sequence: MSLPSGHTTGHTDQVVQRRARCWDIYQRRFSSRSEPVNPGMHSSSHQQQDGDAAMHGAHMDSPVRYTPYTISPYNRKGSFRKQDQTHVNMEREQKPPERRMEGNMPDGTLGSWFKITVPFGIKYNEKWLLNLIQNECSVPFVPVEFHYENMHASFFVENASIAYALKNVSGKIWDEDNEKISIFVNPAGIPHFVHRELKSEKVEQIKLAMNQQCDVSQEALDIQRLPFYPDMVNRDTKMASNPRKCMAASLDVHEENIPTVMSAGEMDKWKGIEPGEKCADRSPVCTTFSDTSSNINSILELFPKLLCLDGQQSPRATLCGTEAHKRLPTCKGSFFGSEMLKNLVLQFLQQYYLIYDSGDRQGLLSAYHDEACFSLSIPFNPEDSAPSSFCKFFKDSRNIKILKDPYLRGELLKHTKLDIVDSLSALPKTQHDLSSFLVDMWYQTEWMLCFSVNGVFKEVEGQSQGSVLAFTRTFIATPGSSSSLCIVNDKLFVRDTSHQGTQSALFTLVPTAFSSSVPAFSQEQQKMLPS
What is the function of this protein?
May function as a tissue-specific nuclear mRNA export factor.
What are the official names of this protein?
Nuclear RNA export factor 3, TAP-like protein 3, TAPL-3.
What is the protein family that this protein belongs to?
Belongs to the NXF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: PRS41_MOUSE
Sequence: MGIQGPVLLLLLLCVMLGKPGSREESQAADLKSTDIKLLSMPCGRRNDTRSRIVGGIESMQGRWPWQASLRLKKSHRCGGSLLSRRWVLTAAHCFRKYLDPEKWTVQLGQLTSKPSYWNRKAYSGRYRVKDIIVNSEDKLKSHDLALLRLASSVTYNKDIQPVCVQPSTFTSQHQPRCWVTGWGVLQEDLKPLPPPYHLREVQVSILNNSRCQELFEIFSLHHLITKDVFCAGAEDGSADTCSGDSGGPLVCNMDGLWYQIGIVSWGIGCGRPNLPGIYTNVSHYYNWIETMMILNGAVRRDLALPLLSITLLQAPWLLRPT
What are the official names of this protein?
Serine protease 41, Testis serine protease 1, TESSP-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: FBCD1_MACFA
Sequence: MLCTVLLALAVLLAVAVTGAVLFLNHTHTPGTAPPPVVSTGAAGANSALVTVERADSSRLSILIDPRCPDLADSFARLESAQASVLEALTEHQAQPRLVGDQEQELLDTLADQLPRLLTRASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVGDVLDALQRDRGLGRPRAKADLQRAPARGARPRGCATGSRPRDCLDVLLSGQQDDGIYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQTAYELHVDLEDFDNGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHTSYADGVEWSSWTGWQYSLKFSEMKIRPVREDR
What is the function of this protein?
Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts.  Can facilitate the endocytosis of acetylated components (By similarity).
What are the official names of this protein?
Fibrinogen C domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: LOLB_SHIB3
Sequence: MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTHGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKTHPAMPANMELTDGGQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DTD_PECAS
Sequence: MIALIQRVSSASVTVEGNIIGEIDKGLLILLGVEQGDDEQKATRLCERVLGYRIFADDDGKMNLNVRQAGGNVLVVSQFTLVADTQRGMRPGFSRGADPSEADRLYQYFVEQCREQGVHTETGQFAADMKVALVNDGPVTFWLQT
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U21_HHV7R
Sequence: MWTILLFCVPVIYGELYPDFCPLAVVDFDVNATVDDLLLFDISLSKQCSDDKIRHSAVAAMTDNAFFFGNSETQIETDFGKYLAFNCYQVFSTLNHFLFKNFKKTKGLMKRYDKLCLDVESYIHIQIICSPFKSFIRLRRMNETGISPRILETTFYLQNKRNSTWVAIKNYLGEDDPFTYRIWHTLTHAKNFLINSCENDFNQLFFWQRKYLSLAKTFEATFKQGFNPMIEQRNEQRYRTNNIDCSFSKFRQNGVKVAVCKYTGWGVSGFGSLEVLQKIKSPFGEEWKRVGFNSTGAFTPLYGSDVLWGLIFLRVEMTTYVCTCTNKNTGTQIQVTLPDVDLDLLDSEKTSSNVFVDMLCYTLIAILFLAFVTAVVLLGVSCLDGVQKVLTWPLQHIQKEPVSEKIINLTNLMFGQEPLPKKESLKQQCL
What is the function of this protein?
Binds to MHC class I molecules in the endoplasmic reticulum and targets them from the Golgi directly to the lysosomes.  Once in the lysosomes both proteins are degraded.  In consequence, surface class I molecules are down-regulated and infected cells are masked for immune recognition by cytotoxic T lymphocytes.
What are the official names of this protein?
U21 glycoprotein, gp60.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U21 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: ARLY_LACLS
Sequence: MVEKLWGGRFEASLDKQTEEFGASIKFEQRLAPFDLKGSLAHVKMLGETGIITAEEATTIANGLIKVEEKLMKGQIEFKIENEDIHMNMETYLHDEIGPLAGKLHTARSRNDQVATDMHLYLKSVLSDLLKALRTLRETIVNLSVNHVDTLMPGYTHLQHAQPISFAQHLMAYYQMFTRDFDRFEFNVKHTDMNPLGAAALAGTTFPIDRELTTNLLQFEKAYANSMDAVSDRDFILEFLSNSSLLMMHLSRLCEELLLWSSHEFNFVSLSDNYSTGSSIMPQKKNPDMAELIRGKSGRVYGNLMSLLTVMKGLPLTYNKDLQEDKEGMFDSADTILTSLSVMDGMLSTMTVNRVNMEKATEQDFSNATELADYLAAKGLPFREAHELVGQLVLTCIKKGIYLQEVSLKDYQALSQLIEEDVYEILQSRTAVSRRNSLGGTGFESIKKQIEQAKKELQK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCRB_STAA8
Sequence: MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVVFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.  To a much lesser extent, is also able to use geranylgeranyl diphosphate (GGPP; C20) as the prenyl donor.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: ATPF_PROM4
Sequence: MISSLFFATKGFGLNLNLFETNVINLAVVIFGLYKFLPNFLGGILERRRSAILADLKDAEDRLTEANTALAKAKNELASAEQKAEKIRSDCKVRAEAIRLESEKKTVEEMARVKQGAAADLNAEASRVSTQLRREAAKLAIEKALVSLPNKLDEKAQLNFISQSIKNMGKD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SSRP_BAUCH
Sequence: MKNQTPCRVSKITTITQNKRVRYEYFIEQEFEAGISLLGWEVKSLRAGIVHINDSYILLKDSEAFLLGATLRPLIVASSHILYSPMRSRKLLLRRRELDTLLGKVHRKGYTIVPISLYWRNSLAKIQLGIAKGKKQYDKRHCIKEREWLLNKARITKLVHR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: TBP_DROVI
Sequence: MDDIMSPNFSIPSIGHAPTPIHHSLDADQQIEALPHQVYHPAALDPTPTATTTVQQQQQPDGNNGVSAADGSGGSNLFGHEPSIPLAHKQSYQPSASYQQQQQQQQNQSSNTGGTTPQSLMQPQTPQSMMSHMMPMTSAAPPDASLSNIHQTMGPSTPMTPATPGSADPGIVPQLQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAPVIMRIREPRTTALIFSSGKMVCTGAKGEDDSRLAARKYARIIQKLGFRAKFLDLKIQNMVGLCDVKFPIRLEGLVLTHCNFSRYEPELFPGLIYRMVRPRIVLLLPAPGKVVLTGAKVRQEIYDAFDKIFSILKKFKKQS
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MCRB_METTH
Sequence: MAKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTKVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPGVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase I subunit beta, MCR I beta, Coenzyme-B sulfoethylthiotransferase beta.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_AFIC5
Sequence: MYRAVTRQIEVLVEPEFLPERSSPEKQQFFWAYSITIVNGGPDSVQLKTRHWVITDGFGQQQEVRGEGVVGEQPVIGPGERYEYTSGVPLTTSSGFMTGSYQMVTEDGEAFDLAIPLFSLDSPDIRRTLN
What are the official names of this protein?
Protein ApaG.
Protein: SCAF8_MOUSE
Sequence: MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKVPGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKNNVFKSEIIQPLLDMAAGIPPPVVTPVLASTTAAMSNTPGTPVTPVTPANVVQGLPDPWVSQIANTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQLTAAAAAANTLTPLDQGVSFNKKLMDRFDFGEDSEHSEESKKEMPTPQLSHVSESVNNSIFHQIAEQLQQQNLEQLRQQLLEQQQPQKVTPQDSQEGTFGSEHSASPSQGSSQQHFLEPEANLDDSIDIQQQDMDIDEGQDVVEEEIFEPEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSHSREKKRKASRSYSSERRAREREKERQKKGLPPVRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQDSFRALQKLSSGSYKIGSKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLDGFAEGGMIDQETVNAEWETVKASEPVKEPVQTAQSPAPVEKESVVTTQAEVFPPPVAMLQIPVAPAVPAVSLVPPAFPVSMPVPPPGFNPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPAIPPVVPTSLVQPPLSMTPEAVKDVGFGSLVLPSGSVAGSLAPSTLPAGNVFNPPSKAEPEEKVPHLIEHQIPSGENTRPVIPSDIPSSAAMLAQPPGASSTSGILCVQRPNVSSNSEILGVRPANVSNSAAIMGAQPPNILNNSGILAIQPPNVSSGSGLLGVLPPNLPNNSGLVGLQPPNVTSPAGLLGTQPPIGPQNLPPLAIPAQRMPALPMLDIRPGLIAQAPGPRFPLLQPGIPPQRGIPPPSVLDAALHPPPRGPFPPGDLFSQPERPFLAPGRPSIDNVPNPDKRIPLGNDNIQQEGDRDYRFPPIETREGITRPPQVDVRDVVGRRLDPREGPGRPPLDARDHFGRPPVDMRENLVRPSLDHLGRRDHFGFPPEKPWGPRDFDEREHRVLPVFGGPKGLHEERGRFRAGNYRFDPRSGPWNRGFGQEVHRDFDDRRRPWERQRDRDDRDFDFCREINGNRLGRDRIQNTWVPPPHARVFDYFEGATSQRKGDNVPQVNGENTERHAQPPPLPVQKDPELYEKLASSGDVDKEESGTVAGVESEAVVESTETEGT
What is the function of this protein?
Anti-terminator protein required to prevent early mRNA termination during transcription.  Together with SCAF4, acts by suppressing the use of early, alternative poly(A) sites, thereby preventing the accumulation of non-functional truncated proteins.  Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A), and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation.  Independently of SCAF4, also acts as a positive regulator of transcript elongation.
What are the official names of this protein?
SR-related and CTD-associated factor 8, RNA-binding motif protein 16.
What are the subcellular locations of this protein?
Nucleus. Nucleus matrix. Note=Detected in granular nuclear foci which correspond to sites of active transcription.