PharMolix/UniProtQA huggingface dataset:
Protein: IRU_DROME
Sequence: MAEAMVVEDRPAEAKRFFCHMCNVEINIPNSDFTCPLCANGFVEELPANAPEMDSSTAGASGSARSGSSGSGSSGSHDTLSRGSSSSGSQVNVESLRNDIVSLLNMRNVPNLEITIEPNRRHSNVLHLGGFGGPSGSDSARGLTAGGRVRPANLDRLDNVLFDFLQSLPLAGATAEIVTGPGGGGVGGGGNSHMFFMGNPGDYAWGREGLDTIVTQMLNQMETSGPPPLSAQRINEIPNVQINAEEVNRKIQCSICWDDFKIDETVRKLPCSHLYHENCIVPWLNLHSTCPICRKSLADDGNDADDEFVMLDAFGPEMAADGSNSERRSASTATGTDNPSPANNPSQAAAEGGRTRPDANPAQAARNNIFTFDDDNMFLD
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates (PubMed:30503771).  Recognizes miRNA-empty Ago1 and triggers its degradation via polyubiquitination independently of the Bag6 complex (PubMed:30503771).  By targeting miRNA-empty Ago1, eliminates dysfunctional Ago1 not able to bind miRNA and thereby plays a role in the quality control of miRNA-mediated silencing (PubMed:30503771).
What are the official names of this protein?
E3 ubiquitin-protein ligase Iruka.
Protein: GLYA_MYCLE
Sequence: MVAPLAEVDPDIAELLGKELGRQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGLPGRRYYDGCEHVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHLTHGMRLNFSGKLYETGFYGVDATTHLIDMDAVRAKALEFRPKVLIAGWSAYPRILDFAAFRSIADEVGAKLWVDMAHFAGLVAVGLHPSPVPHADVVSTTVHKTLGGGRSGLILGKQEFATAINSAVFPGQQGGPLMHVIAGKAVALKIATTPEFTDRQQRTLAGARILADRLTAADVTKAGVSVVSGGTDVHLVLVDLRNSPFDGQAAEDLLHEVGITVNRNVVPNDPRPPMVTSGLRIGTPALATRGFGEAEFTEVADIIATVLTTGGSVDVAALRQQVTRLARDFPLYGGLEDWSLAGR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD5_MOUSE
Sequence: MNTNDAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSKLFPNKEAPMDSSDLDPSMMFDAGEIIDTGSDYDNQDDDQLNVFGEDTEGGFMEDLRKCKIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLRKVNAEGTPEQVFLQLCTAIDSVF
What is the function of this protein?
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  Active on AMP and dAMP with ATP as a donor.  When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP.  Also displays broad nucleoside diphosphate kinase activity.
What are the official names of this protein?
Adenylate kinase isoenzyme 5, AK 5, ATP-AMP transphosphorylase 5.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POR_DAUCA
Sequence: MALQAASFLPSSFSINKEGKANVSLKETSLFGVTFSDSLRTDFSSLRTRRGCRQISQTGAIRSQAVATTPSVNRATGEGKKTLRKGSVIITGASSGLGLATAKALAETGKWHVIMACRDFLKAERAAKSAGMPKENYTIMHLDLASLDSVRQFVETFRRSERPLDVLVCNAAVYFPTAKEPTYTADGFELSVGTNHLGHFLLSRLLLDDLNKSDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLAGGLNGMNSSAMIDGAEFDGAKAYKDSKVCNMLTMQEFHRRYHEETGITFASLYPGCIATTGLFREHIPLFRTLFPPFQKYITKGYVSEAESGKRLAQVVSEPSLTKSGVYWSWNKDSASFENQLSEEASDVEKARKVWEVSEKLVGLA
What is the function of this protein?
Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
What are the official names of this protein?
Protochlorophyllide reductase, chloroplastic, PCR, NADPH-protochlorophyllide oxidoreductase, POR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ANR37_XENTR
Sequence: MLQLCDSECDGLSSLMECGGAVNSPGDTLGQSPAHLAACGGQAFFLLWQLQTGVDVNQQDCFGEAPIHKAARSGSMECLSLLIASDARIDMCNKDGHTAEDVALSCGFLDCARYLATIKLTQDTFSRAQSSLHNLKETAAGVKRGQCCQSISHGKRRRSDGFV
What are the official names of this protein?
Ankyrin repeat domain-containing protein 37.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RL11_CHLL3
Sequence: MAKKVIGFIKLQIPAGAANPAPPVGPALGQKGVNIMEFCKQFNAKTQSEAGMIIPVVITVFSDKSFTFITKTPPAAVLLLKEAKLQKGSGEPNRNKVGTVTREQVKKIAELKMPDLNAFDLRGAEEMIMGTARSMGIVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HPBP1_MACFA
Sequence: MSDEGSRGSRLPLALPPASQGCSSGGGGGGGGGGSSSAGGSGNPRPPRNLQGLLQMAITAGSEEPDPPPEPMSEERRQWLQEAMSAAFRGQREEVEQMKSCLRVLSQPMPPTAGEAEQAADQQEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEHRGTLCSMGMVQQLVALVRTEHSPFHEHVLGALCSLVTDFPQGVRECREPELGLEELLRHRCQLLQQHEEYQEELEFCEKLLQTCFSSPTDDSMDR
What is the function of this protein?
Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding.  Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of target proteins (By similarity).
What are the official names of this protein?
Hsp70-binding protein 1, HspBP1, Heat shock protein-binding protein 1, Hsp70-interacting protein 1.
Protein: QUEF_BACC0
Sequence: MAGRLDEDLKDVTLLGNQNTKYLFEYSPEILEVFDNNHPNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPEQRMVESKSLKLYLFSFRNHGDFHEDCMNVIMNDLIKLMDPRYIEVWGKFTPRGGISIDPYCNYGRPGTKYEQMADYRMMNHDLYPETIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCXB_ECOLI
Sequence: MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHAKTVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPDCNAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQKQGIPLDAGSWQAICDAARQIGMPEETLQAFCQQLAS
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of 2-oxoglutarate, phenylpyruvate and (4-hydroxyphenyl)pyruvate, leading to the respective 2-hydroxycarboxylate in vitro.  Shows a preference for NADPH over NADH as a redox partner.  Do not catalyze the reverse reactions.
What are the official names of this protein?
Hydroxycarboxylate dehydrogenase B, 2-oxoglutarate reductase, Hydroxyphenylpyruvate reductase, Phenylpyruvate reductase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family.
Protein: HIS5_CHLCH
Sequence: MVFIADYGAGNLRSVLKAFEFLGIKAIVSNDPRKMAGYRKVLLPGVGAFGQAMQSLEALGFVSALLEHVDKGGHLLGICLGMQLLLSESEEMGTHKGLNLVPGKVKHFVSSSDKIPQIGWNAVDFSKQSDLFRNVADHSFFYFVHSYYCETESVEAVAATTLFAGQNFCSAIEKNGIFAVQFHPEKSADAGLKVLANFAEL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLUQ_NOCFA
Sequence: MADVQAPTIGGAGRYAPSPSGDLHLGNLRTALLAWLFARASGRRFLLRVEDLDRVRPGAQQRQLADLRAIGLDWDGPVVCQSQRRTRYEAAITRLREAGLTYECYCTRREIQQAATAPHGPLGAYPGTCRDLSDADRAERRAQGRPAALRLRAERTDFEIVDQLHGRYRGPVDDVVLRRGDGLPAYNLAVVVDDAAQGVDQVVRGDDLLPSTPRQAYLATLLGLPVPAYAHVPLVLNKDGQRLAKRDGAVTLADQQRAGKSPEQVLALLTDSLGLPPRPPRELLADFDPARLPREPWILTDNGLLQPSECP
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: KATG_EDWTA
Sequence: MGNNNEFSSGKCPVMHGGMTSAGMASKDWWPNALNLDILHQHDTKTNPMGQQFNYREALKQLDVQALKDDLRALMTDSQPWWPADWGHYGGLMVRMAWHSAGSYRIADGRGGAGTGNQRFAPLNSWPDNVNLDKARRLLWPIKKKYGNKISWADLIVLAGTMAYESMGLKTFGFAFGREDIWHPEIDTYWGSEKEWLAPSGSEGSRYSGERDLENPLAAVMMGLIYVNPEGVDGHPDPQKTANDVRVTFARMAMNDEETVALTAGGHTVGKCHGNGSAANLGAAPEGADLQEQGLGWNNHTTRGIDRDTVSSGIEGAWTSKPTQWDNGYFDMLLGHEWTLTKSPAGAWQWVPIQIAEEDKPVDVEDPSIRLLPIMTDADMAMKVDPTYRQIAERFRQDPAYFSDVFARAWFKLTHRDLGPKSRYFGPDVPQEALIWQDPVPAGRSEYDVAAVKAKIAASGLSIADMVSTAWDSARTFRGSDKRGGANGARIRLAPQNTWEGNEPARLAKVLAVLEPIAAEFNVSVADVIVLAGNLGIEQAAKAAGVAIEVPFAPGRGDATQAMTDEASFEVLEPLADGFRNWLKKDYVVTAEELLLDRAQLMRLTACEMTVLIGGMRVLGANYGGSKVGVFTDRIGVLSNDFFVNLTDMSYTWKPTASNLYEIRERANGALKWTASRVDLVFGSNSILRAYAEVYAQDDNKEKFVRDFVAAWTKVMNADRYDLR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: MRGX2_PONPY
Sequence: MDPTTPAWGNESTTMNGNDQALPLLCGKETLIPVFLILFIALVGLVGNGFVLWLLGFCMRRNAFSVYVLSLAGADFLFLCFQLINCLVYLSNFFCSISIDFPSFFTTVMTCAYLAGLSMLSTISTERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFFFSDGDSGWCQTFDFITAAWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLLCGLPFGIQWFLILWIWENSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGTFRKQWRLQQPILKLALQRALQDTAEVDHSEGCFRQGTPEMSRSSLV
What is the function of this protein?
Mast cell-specific receptor for basic secretagogues, i. e.  cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core.  Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium.  In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction.
What are the official names of this protein?
Mas-related G-protein coupled receptor member X2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VKT39_CYRSC
Sequence: MGTARFLSAVLLLSVLLMVTFPALLSAEYHDGRVDICSLPSDSGDCLRFFEMWYFDGTTCTKFVYGGCGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Protein with unknown function.
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hs1g, U15-TRTX-Hs1g, Huwentoxin HW11c39.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHI_PERCD
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PSBT_GOSBA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKILTKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GMT_ASPCL
Sequence: MADDKKTNDYTVEMDKLDQGSKNFEAPLPPVQPRSAPNAQLANNPILPVLAYCGSSIMMTVMNKYVLSGTDFNLNFLLLCVQSIVCIVAIQTCKASKLITYRDFNADEAKKWFPITLLLIGMIYTGSKALQFLSIPVYTIFKNLTIILIAYGEVLWFGGSVTGLTLFSFGLMVLSSIIAAWADIKHAVESSGDATAKVSTLNAGYIWMLINCLCTSSYVLGMRKRIKLTNFKDFDTMFYNNLLSIPVLLVLTFLMEDWSSANITRNFPPADRNGIMFAMILSGLSSVFISYTSAWCVRVTSSTTYSMVGALNKLPIAVSGLIFFDAPVTFPSVSAIVVGFVSGIVYAVAKIKQNAKPKTGVLPTSNPVSASSQSMRDSLRS
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-mannose transporter, GMT.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MIAB_BACC4
Sequence: MNEQQRLASQQANSSTKKEEKDYSKYFENVYQPPSLKDAKKRGKEEVKIERDFGLPEEFRNFGTGRKFYIRTYGCQMNEHDTEVMAGIFTALGYEPTFSTEDADVVLLNTCAIRENAENKVFGELGHLKSLKRRNPDLLIGVCGCMSQEESVVNKIMQKNQHVDMVFGTHNIHRLPYILKDAMFSKETVVEVWSKEGDVIENLPKVRRGDIKAWVNIMYGCDKFCTYCIVPYTRGKERSRRPEDIIQEIRHLAANGYKEITLLGQNVNAYGKDFEDIEYGLGDLMDELRKVDIARIRFTTSHPRDFDDHLIEVLGKGGNLVEHIHLPVQSGSTDMLKIMARKYSREHYLELVRKIKEAIPDVVLTTDIIVGFPNETDEQFEETMSLYREVGFDTAFTFIYSPREGTPAAKMKDNVPMEVKKERLQRLNTLVNTLAIEKNSRYKGQIVEVLVDGESKNNPEVLAGYTRTNKLVNFVASKSLIGQLVKVKITEAKTWSLNGELVEEPIEVK
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPC3_METJA
Sequence: MDAVIDTSVIIEIFRGNKDTLYQICDYNCKITSITVFELYCGNLKENEMIMIDSLPKLNFDDKSSKIAGNIFKKLKKEGKIPSVKDLLIASIFY
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB3 (By similarity).
What are the official names of this protein?
Ribonuclease VapC3, RNase VapC3, Putative toxin VapC3.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: PSUG_SALTO
Sequence: MPGLLRARRTDAVRLDAVTTFHLRHGVEVADALRVGRPVVALESTIVSHGLPRPDNLRVAREIEQTVRDAGAVPATIGMVAGQLVVGLDDAELTRLATVDDVAKLSVRDLAVAAATDADGATTVAATSAVAAAAGIRVFATGGLGGVHREAAQSFDESADLTTLARTPIAVVCAGVKSILDSGATLERLETLGVGVVGYRTRRFPGFYLTDGGFDLDWSVDSPEQVAAALAAQEQHGLHSGGLVVANPLPTDEQLDPALHDRTLAEGLMLLRREGVTGKAVTPFLLAHFHSATEGASLAVNIRIILRNADLAAQIAVASAARQA
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: SYFA_BACC2
Sequence: MEARLKELKQKALELIEEAKELKGLNDVRVAYLGKKGPITEVLRGMGKLSAEERPRMGALVNEVREAIQTRLEDKISNLEKAVIEAKLATETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFGEDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HS2ST_CRILO
Sequence: MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRAKLERAIARHEVREIEQRHTMDGPRQDAAVDEEEDIVIIYNRVPKTASTSFTNIAYDLCAKNRYHVLHINTTKNNPVMSLQDQVRFVKNITTWNEMKPGFYHGHISYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATDLYRTGKKSHLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN
What is the function of this protein?
Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS).  2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes.  Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity).
What are the official names of this protein?
Heparan sulfate 2-O-sulfotransferase 1, 2-O-sulfotransferase, 2OST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RL17_DESOH
Sequence: MRHRKSGVKLGRTGSHRNAMFRNMVTSLLKHEKIQTTDAKAKELRRWADHVITLAKRGDLHARRQVMAIVREKNVVHKLFAEAAERFGSREGGYTRLTKIGARPGDAAPVTLIELVSLTETTEKKKKKPAKTAAKPAPTPSAPAVEKEAAADTPAPAAEESAPAKAAEPEAEAAAPEAEAAPEEPEVPAADTPVEDDGASEEAPPKTE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: XERC_ESCF3
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNAS1_ACOCA
Sequence: MGLEKSLILLPLLVLVLAWVQPSLGKETPAMKFERQHMDSAGSSSSSPTYCNQMMKRREMTKGSCKRVNTFVHEPLADVQAVCSQKNVTCKNGKKNCYKSRSALTITDCRLKGNSKYPDCDYQTSHQQKHIIVACEGSPYVPVHFDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPED_CLOAB
Sequence: MKVNIDNKIKLHGFNNLTKTLSFNMYDICYAKSAEDREAYISYIDEQYNADRLTEILTNVTEIIGANILNIAKQDYDPQGASVTILVCENPIEEERKEALVKETPGPLPEIVLAHLDKSHITVHTYPEYHPDEGICTFRADIDVSTCGMISPLRALNYLVHSFEADIMTMDYRVRGFTRDITGRKLFIDHKINSIQNYIPSNIKTKYNMIDVNVYQENIFHTKCRLKQFDLDNYLFGYTKKDLYPKERKKITHKLKKEMDEIFYGKNFDEVYYK
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: ARSA_PROVB
Sequence: MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNLQLGAEPTKIKENLHAIEVNPYVDLKENWHSVQKYYTRVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKSTGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIVRPLSKPLSKMSDKIAYYIPPEDAIESVDQVFDELEDIRDILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKVDMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVFAHDIYGDTDPSDMMYDEPPIKFVRKGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGNQRKIITLPVSLTGLEPGDAVFRDKWLHIPFDLEKQGQHHRTREFNKA
What is the function of this protein?
Anion-transporting ATPase.  Catalyzes the extrusion of arsenite (By similarity).
What are the official names of this protein?
Putative arsenical pump-driving ATPase, Arsenical resistance ATPase, Arsenite-translocating ATPase, Arsenite-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
Protein: EI3D1_DROAN
Sequence: MSETINTASQFPTFEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTSTSNNDKKYQNKYASTFGTGNQYSYYHEEDETTFHLVDTARVQKPPHQRGRFRNMRNSRSGRGRNARGGINTHGMTTLSGKNVKARDPRRGMGKKFGNRGPPPKMRESSVAVRADWASIEEMDFPRLIKLSLPNIKEGVDIVTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTIGNVFATDAILATIMCSTRSNYSWDIVIEKVGEKIFMDKRDHTEFDLLTVNETSVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEAKFKFQESNPFISEDEDIQVASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGEPQFMSIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDGEGFQQVYNYANNGNKI
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-1, eIF3d-1, Eukaryotic translation initiation factor 3 subunit 7-1, Eukaryotic translation initiation factor 3 subunit p66.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.