PharMolix/UniProtQA huggingface dataset:
Protein: ATPE_ERWT9
Sequence: MAMTFHLDVVSAEEQMFSGTVQSIQVSGSEGELGIRPNHAPLLTAIKPGMIRIVKQHGEEEVIYLSGGVLEVQPGAVTVLADTAIRGSDLDEARALEAKRKAEAHMNSSHGDVDFAVASAELAKAIAKLRVIELTKNAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TTCA_TERTT
Sequence: MDQLTRKNRLEFNKLQKRLRRHVGRAIADYNMIEEGDRVMVCLSGGKDSYGMLDILLSLQRTAPVKFELVAVNLDQKQPGFPEHVLPAYLDTLDIEYHIVERDTYSIVKSVVPEGKTTCGLCSRLRRGTLYGFAEKIGATKIALGHHRDDIVETLFLNLFYAGRLKAMPPKLRSDDKRNIIIRPLAYCPEEDLEAFAQARAFPIIPCNLCGSQENLQRQVIKEMLRGWDKQFPGRVETIFAALQRVSPSQLADNALFNFTDLTLDRSAPAAIEDDAPLSWSDLATTEDTTDAVNIINAVNIG
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_LISMC
Sequence: MIQQESRMKVADNSGAREVLTIKVLGGSGRKTANIGDVVVCTVKQATPGGVVKKGEVVKAVIVRTKSGARRQDGSYIKFDENACVIIRDDKSPRGTRIFGPVARELRENNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CBIM_CHLL2
Sequence: MKTILRPFTLLSRSIFLALFVLFLWSPDAHAMHIMEGFLPPSWSLFWWVLTLPFLVVGFRSLRKIVDANPRMKLLLAMAGAFAFVLSSLKIPSVTGSCSHPTGVGLGAVLFGPSVMSVLGVIVLLFQALLLAHGGLTTLGANAFSMAIAGPFVSYGIYRLMVMSKAPEWLAVFLAAAIGDLMTYVVTSLQLALAFPSVTGGIAASLGKFMTIFALTQVPLAISEGILTVMVFSAIREYASELFPASGTLAKEGV
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTA_PONAB
Sequence: MLRAKNQLFLLSPHYLKQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEITKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSV
What is the function of this protein?
Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.
What are the official names of this protein?
Methylmalonyl-CoA mutase, mitochondrial, MCM, Methylmalonyl-CoA isomerase.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA mutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion. Cytoplasm.
Protein: Y4761_MYCUA
Sequence: MPRTADDSWDIATSVGATAVMVALARAAETASETPLIRDQFAEPLVSTPELAAVREQVAAWWAQTDDDDDPDFTVDSQQMTDYLAVRTHFFDSYFIDAVAAGIRQVVILAAGLDSRAYRLDWPGGTMVYEIDLPKVLDYKEHTLARHGAAPVAALRAVPVDLRHDWPQALRDAGFQTSLPTAWLAEGLLPFLPAAAQHALFTAIDANSATGSRVAVEMFGVDEDARRAAEERAQRWARQRAKRQARGQDTSFDPFDLWFDDEGQPDPADWFAAHGWTTDSVQVGAEALRLGRTATSQEGPFVNRFVTAGKP
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MUL_4761.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: TYRP2_MOUSE
Sequence: MGLVGWGLLLGCLGCGILLRARAQFPRVCMTLDGVLNKECCPPLGPEATNICGFLEGRGQCAEVQTDTRPWSGPYILRNQDDREQWPRKFFNRTCKCTGNFAGYNCGGCKFGWTGPDCNRKKPAILRRNIHSLTAQEREQFLGALDLAKKSIHPDYVITTQHWLGLLGPNGTQPQIANCSVYDFFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERELQRLTGNESFALPYWNFATGKNECDVCTDELLGAARQDDPTLISRNSRFSTWEIVCDSLDDYNRRVTLCNGTYEGLLRRNKVGRNNEKLPTLKNVQDCLSLQKFDSPPFFQNSTFSFRNALEGFDKADGTLDSQVMNLHNLAHSFLNGTNALPHSAANDPVFVVLHSFTDAIFDEWLKRNNPSTDAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTAEQLGYNYAVDLSEEEAPVWSTTLSVVIGILGAFVLLLGLLAFLQYRRLRKGYAPLMETGLSSKRYTEEA
What is the function of this protein?
Plays a role in melanin biosynthesis (PubMed:33100333).  Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:1537333, PubMed:1537334).
What are the official names of this protein?
L-dopachrome tautomerase, DCT, DT, DOPAchrome conversion factor, DOPAchrome isomerase, DOPAchrome oxidoreductase, L-dopachrome Delta-isomerase, SLATY locus protein, Tyrosinase-related protein 2, TRP-2, TRP2.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Note=Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Protein: HSE1_COCIM
Sequence: MFRAQQNAYDDIVAKATDENLTSENWEYILDVCDKVSADESGAKDAVASMIKRLAHRNANVQLYTFELANALSQNCGPKAHRELASKSFTDALLRLANDRNTHPQVKSKILEHMEQWTEMFSSNPDFGIMEHAYMKLKSQNPNIQPPSKPTKRQITELDRQKEEEELQMALALSIKEKQSETSKQQDGSSQHVVTTSAQAEAAPSQGIPSGTTAATVSRVRALYDFQPSEPGELQFRKGDIIAVLESVYKDWWKGSLRGQVGIFPLNYVEKLSDPTQEELQREAQMEAEVFAEIKNVEKLLALLSTSSPELNVQENEEITKLYHSTLAIRPKLIELIGKYSKKKDDFTQLNEKFIKARRDYEALLEASMTHPAQSHYNRPAQPPFAYPPSGTHPGYPHHAPPQQEPQRYYTPRPSQDPQSAPHNTPGYYGAEPSTLPYPPDSQSPDFRKHTATGSMQLPQQQPSQPPQDAYSQGATTHYPPKTTYDHPQELGTSVYDSPQGNAPQAIQHSYHPAMQQELQQQQATGAEPTQRPYSPQENPPPQAPSSNPPYPVQTPQEPPQQSFAPPAPMHQPPPIPSVAPSQGAYGGGYQAYQPPTTQQHSPTSNPAAFYR
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein HSE1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CICA_CAUVN
Sequence: MAKRSWMAKGLSASRPMTGEMGHEPLLVAFDFDGTLTVKDSFNAFLKWRAGPRWSFGVLRLTPALIAYVFDRNRGKLKAAAVRQFLKGATVAQIENDARAFAEAFAPSLLRPDAVAVWRGWRAKGAKMVIVTASPDLIVAPFARGLGADLLIGTRLRCSDDGRILGGLDGNNCRAKEKVIRLREVFGPDVRLTAAYGDTSGDTEMLAIADEKGYRIFRGKPA
What are the official names of this protein?
Protein CicA.
Protein: ACTB_HORSE
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.  Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: THRB_HUMAN
Sequence: MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
What is the function of this protein?
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C.  Functions in blood homeostasis, inflammation and wound healing.
What are the official names of this protein?
Prothrombin, Coagulation factor II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: WHIA_STRP1
Sequence: MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSITTENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADSFFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQLMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDINRANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQVADALEFPITKSGVNHRLRKINKIADDL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: DBP3_ASPTN
Sequence: MTKRDYQNDTTAESRPTKKSKGEKKVKETKEKKEKKVKSYVQNPSLDTLPQAEIDEFLASNSIKITDTLPDATPLRPIISFSHLPECNSNLYEQLNSFKSPTSIQSATWPLLFGGRDVIGIAETGSGKTLAFGLPCLKKIEDSKKKKSKPYQPMAVIISPTRELAMQIHDQLQKFAGPVGAKVACIFGGVRKDEQREVLKTANIVVATPGRLKDLQNDGSVDLGKVRYLVLDEADRMLDKGFEQDIKDIIQPMPVSKRQTVMFTATWPPVVRELASTFMSSPVTVTIGGDPSADPRANTRIKQVVEVVKPHEKEGRLVQLLKQHQRGAEKVLAFCLYKKEATRIERFLQSRGFKVAGIHGDLSQQERFRSLDAFKTGAATVLVATDVAARGLDIPAVKLVINVTFPLTVEDYVHRIGRTGRAGAEGHAITLFTETDKAQSGALINVLKAAGQEVPEELLKFGGTVKKKQHDAYGAFFKDVDTTKAATKIVFDD
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DNLJ_ANADF
Sequence: MRADADRDSAETRAAELRARILDADHAYYVLDRPVLADAEYDRLVRELAEIEAAHPELATSDSPTQRVSGAPSERFERVVHREPMLSLGNIQSDGELDEFDARVHRLLGLAGDVQVGYVAEPKLDGLAVELVYEGGRLVQGSTRGDGVNGEDVTANLRTVGRTRANRGVPERLAGEVPPRVEVRGEVLLFKEHFEAMNRQILRAGDEPFANPRNAAAGSLRQLDWRVTARRPLSFIAYEALVPGAEPGGARAGPWAWRTHAEKLEALARWGFETNAENERCEGIAAVKAYRDRMAERRFALPYDTDGVVVKVDDLDWRRRLGAASKFPRWAVAFKYPPQEEATRIRRIWASVGRTGILTPVVDFEPVRLSGAMVSRATLHNEDEMRRKDVLEGDWILVRRAGEVIPEVVMPLKERRTGEERPFAFPAECPICGAKVVREEGEKVYRCTGAACPAQLVGRLTHFAQRRAMDIDGLGDKLALGLVERGLVKDFADLYAVPFPAWQELFSRPRKEERDAKAELPQKSAQNMVDALERSKATTLRRLLFALGIPQVGEATAATLARHFGELARFMDASEDALLAVRDVGPETAREIRAWTEEPQNRRVVERLLAAGVRPAPETVDAGGPFAGKTVVLTGGLAALSRDDAKAEIERRGGKVSGSVSRKTDLVVAGAEAGSKLEKAQALGVRVVGEEEFLRMLEE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DNLJ_BORA1
Sequence: MSAFEQAAREQAARLRAEIAQHNIRYYVYDEPSITDADYDALMRELMALEAQHPELVTPDSPTQRVGAAPLAEFGSVRHAVPMLSLGNGFEDEDVLAFDKRVSDTLREAGLLGPAEQAHYFCELKLDGLAISLRYENGELVQAATRGDGQEGEDVTANIRTIRAIPLQLRAGAPAVLEVRGEVLMNRADFEKLNQKQAARGEKIFVNPRNAAAGSLRQLDPRVTAQRPLRFFAYSWGEVQGLSRDDAPAFDEASPGLVSTLPRDTHGGMLDWLAGLGLPVNVRFNHKAQGAEGLLAFYRRIGAERGSLPYDIDGLVYKVDALAAQRVLGYVARAPRWALAHKFPAEEATTELLDIEVQVGRTGAITPVARLKPVFVGGVTVTNATLHNEDEIRRKDVRIGDRVIVRRAGDVIPEVVGPVLEKRSGELPQFVMPTHCPICGSAIERLVDEAIARCTGGLFCPAQRKQTLLHAAGRKALDIEGLGEKLVEQLVDNGSLKTLADVFRLNAFELAALDRMGKKSADNLVAAIDQARRPSLGRLLFALGIRHVGETTARDVARHFGNIDAIMDADEAALLAVPDVGPVVAGSIHRFFQEAHNREVIRELEKQGVHPQAEAQLQSGDLAGKTFVLTGTMPTWSRDEATRHILAAGGKVSGSVSKKTAYVVAGEEAGSKLVKARELGVTILDEDGLKALLSQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MUG1_MOUSE
Sequence: MWKSRRAQLCLFSVLLAFLHSASLLNGDSKYMVLVPSQLYTETPEKICLHLYQLNETVTVTASLVSQSGRKNLFDELVLDKDLFQCVSFIIPRLSSSDEEDFLYVDIKGPTHEFSKRKAVLVKNKESVVFVQTDKPVYKPGQSVKFRVVSMDKMLRPLNELLPLAYIEDPKKNRIMQWRDIKTENGLKQMSFSLAAEPIQGPYKIVVHKESGEKEEHSFTVMEFVLPRFNVDLKVPNAMSVNDEVLSVTACGKYTYGKPVPGHVKINVCRETETGCREVNSQLDNNGCSTQEVNITELQSKKRNYEVQLFHVNATVTEEGTGLEFSRSGTTKIERITNKLIFLKADSHFRHGIPFFVKVRLVDIKGDPIPNEKVFIKAQELSYTSATTTDQHGLAEFSIDTTCISGSSLHIKVNHKEEDSCSYFYCMEERHASAKHVAYAVYSLSKSYIYLDTETSSILPCNQIHTVQAHFILKGDLGVLKELIFYYLVMAQGSIIQTGNHTHQVEPGEAPVKGKFALEIPVEFSMVPMAKMLIYTILPDGEVIADSVNFEIEKCLRNKVDLRFSTSQSLPASQTRLQVTASPQSLCGLRAVDQSVLLLKPESELSPSWIYNLPGMQQNKFVPSSRLSEDQEDCILYSSWLAEKHTNLVPHGTEKDVYRYVEDMGLTAFTNLMIKLPIICFDYGMVPISAPRVEFDLAFTPEISWSLRTTLSKRPEEPPRKDPSSNDPLTETIRKYFPETWVWDIVTVNSTGLAEVEMTVPDTITEWKAGALCLSNDTGLGLSSVVPLQAFKPFFVEVSLPYSVVRGEAFMLKATVMNYLPTSMQMSVQLEASPDFTAVPVGDDQDSYCLSANGRHTSSWLVTPKSLGNVNFSVSAEAQQSSEPCGSEVATVPETGRKDTVVKVLIVEPEGIKQEHTFSSLFCASDAEISEKMSLVLPPTVVKDSARAHFSVMGDILSSAIRNTQNLLHMPYGCGEQNMVLFAPNIYVLKYLNETQQLTQKIKTKALGFLRAGYQRELNYKHKDGSYSAFGDQNGEREGNTWLTAFVLKSFAQARAFIFIDESHITHAFTWLSQKQKDNGCFRSSGSLFNNAMKGGVDDEMTLSAYITMALLESSLPATHPVVSKALSCLESSWKTIEQERNASFVYTKALMAYAFALAGNQNKRDEILKSLDEEAIKENNSIHWKRPQKSRKSEHHLYKPQASSAEVEMNAYVVLARLTAQPAPSPEDLTLSMSTIMWLTKQQNSNGGFSSTQDTVVALDALSKYGAVTFSRSQKTTLVTIQSTGSFSQKFQVENSNRLLLQQVALPDIPGDYTISVSGEGCVYAQTMLRYNMHLEKQLSAFAIWVQTVPLTCNNPKGHNSFQISLEISYTGSRPASNMVIADVKMLSGFIPLKPTVKKLERLEHVSRTEVSNNNVLIYLDQVTNQTLAFSFIIQQDIPVRNLQPAIVKVYDYYETDEMAFAEYSSPCSTDKQNV
What is the function of this protein?
A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor.  While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.
What are the official names of this protein?
Murinoglobulin-1, MuG1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AGAP1_XENLA
Sequence: MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERLDEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRLANYRNTSEIPMVLVGTQDAISGSNPRVIDDSRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHTSVCSTQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPAASTPTPVRKQSKRRSNLFTSRKGSDPDKDKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLSDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSSCAPVASPKTNGLTKEVSGLQISPNTGNVTSSTSVTQMASGPSGISLGSFSRMDGMHQRSYSVSSADQWSEGAVITNSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKVDGLSSTAEEQEENFEFIIVSLTSQSWHFEATSYEERDAWVQAIESQILASLQSCESSKNKSRLTSQNEALALQSIRNLPGNSHCVDCDAQSPDWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPPELIKVMSAIGNELANSVWEGSSQGHVKPCSESPREEKERWIRAKYEQRLFLSPLPCRDLPLGQQLLRATAEEDLRAVILLLAHGSREEVNETCGEGDRRTSLHLACRKGNVVLVQLLIWYGVDVMARDFHGNTALAYAKQAVTSEVRELLLQYGCPDEQFVLMATPNLSRKNNRNNNSNAGGSGLMPTLI
What is the function of this protein?
GTPase-activating protein.  Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system (By similarity).
What are the official names of this protein?
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1, AGAP-1, Centaurin-gamma-2, Cnt-g2.
What is the protein family that this protein belongs to?
Belongs to the centaurin gamma-like family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with the endocytic compartment.
Protein: MOCB_RHIML
Sequence: MKKFIIGIAAAVLVSTAAHAETIGASMAVFDDKFGTLLRNGMEDYAKTLDGVDLQIEDALNDVAKQQSQIQNFIAAGVDAIIVQPVDTDATTVMSKLAADAGIPLVYVNREPVNIDTLPEKQAFVASNEVDSGTLQTREICKLLDGKGKAVVIMGELSNQAARMRTKDIHDVLATDQCKGIEIVQEQTANWQRTQGADLMTNWLSAGIEFDAVIANNDEMAIGAIQALKAAGRSMDSVVIGGIDATDDALAAMAAGELDVSVFQDAVGQGKGSIDAALKLSKGEAVERKIYIPFELVTKANLAEFQGKN
What is the function of this protein?
Involved in rhizopine (L-3-O-methyl-scyllo-inosamine) catabolism.  Could be involved in its high affinity transport.
What are the official names of this protein?
Putative rhizopine-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSTB2_CALS4
Sequence: MKKIEVRDLDLFYGEVQALKKINLDVEPNSVLALIGPSGCGKSTFIRTLNRMNDLIEGVKISGTVLLDGKDIYKEVDVIELRKKVGMVFQKPNPFPMTVYDNVAYGPRIHGIRDKRTLNEIVEKSLKAAALWDEVKDRLHHSALSLSGGQQQRLCIARTLAVEPEVILMDEPTSALDPISTMKIEELIEELKKKYTIIIVTHNMQQAGRVSDYTAFFLNGELVEWGPTDQVFYNPKDKRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL19_BURO0
Sequence: MNLIAKLEQEEIERALAGKTIPDFAPGDTVIVNVNVVEGNRKRVQAYEGVVIAIRNRGLNSNFIVRKISSGEGVERTFQTYSPLLASIVVKRRGDVRRAKLYYLRERSGKSARIKEKLVSKDRAAAASQE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: TPS8_RICCO
Sequence: MAAEAKNDEQQDIARRLAKFPSTIWGCSFASFSLKDSEIESYTQQVEELKGKVKDMLMQSTKEITQNIEVINLLCRLGVSYHFESEIEQQLNLIFASLPSFLNDNGHLDLYTVALLFRVLRQHGRKVPCDVFNKYKDDNGEFKKDITSDVKGLLSLYEASVVSVHGEEILDEALVFTKQHLETLAAQVSPHFEQHIRNALLCPVHYGMERLQARLYISFYEEDESRNEILLKFAKLDFNRLQLLYREELAIVSRWWKDLDLTERLSYARDRIVEVYVWALGCVGSQPQFASSRLLVAKFTQTAMTVDDTYDAYGTIGELRLFTAAFERCSIDAIHELPEYMQYLYKAILKLFEETENDANEGSSYKTSYAKEMFKELTRADLQEGEWFNSLYVPAFDEYLHNASITTTGELLTAAFLLGLKEASMKEIVWVRDAPKIVRNAKLFARLLDDVATHEEEQKRGDCPSSVECYMNEYGVPKEKAYEEIKKILATSWKDINEDYMKQHRVSRTVVNYFINFARMSNFVYKVRDAYTYSTHLKTYVATLFLQPLPV
What is the function of this protein?
Probable sesquiterpene synthase.
What are the official names of this protein?
Probable terpene synthase 8, RcSeTPS8.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: FLIC_SALTY
Sequence: MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin, Phase 1-I flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: NUOD_MYCA9
Sequence: MTAQPEIHLMAGGQDWDEIVTAAGQATDERIVVNMGPQHPSTHGVLRLILEIEGETVTDVRCGIGYLHTGIEKNLEYRTWTQGVTFVTRMDYLSPFFNETAYCLGVEQLLGIADEIPERANVIRVLMMELNRISSHLVALATGGMELGAMTAMFLGFREREMILKVFEAITGLRMNHAYVRPGGLAQDLPDGAEQEVRDLLEILPGRLRDMENLLNENYIWKARTQGVGYLDLTGCMALGITGPVLRATGLAHDLRRAQPYCGYENYDFDVVTHQDCDSYGRYLIRVKEMHESIKIAQQCVDRLRPGPVMVDDKKIAWPADLASGPDGLGNSPKHIAKIMGTSMEGLIHHFKLVTEGVRVPAGQVYVAIESPRGELGVHMVSDGGTRPYRVHFRDPSFTNLQSVAAMCEGAMVADLIAAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y913_TREPS
Sequence: MPKHNKLLGAFGEAYAARWLATRGYIIITRNWRRATGEIDIIAQQDDTIVFVEVKTLRCTSYADLAIIVGKRKQKRICETAKHFLASAREYNHMCARFDVIVLRSDPFRRQDVDIVHLPHAFEDLV
What are the official names of this protein?
UPF0102 protein TPASS_0913.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.