PharMolix/UniProtQA huggingface dataset:
Protein: RF1_FRATF
Sequence: MKDSIKAKLQSLIERHEEVSALLSEAGIISDQNKFRDLSKEYSHLEPIVKAFKEYTQALEDKQAAYEMLNEKDAELVEMAKEELKLANEAIEKLESELQIFLLPRDPNDDANVFLEIRAGTGGDEASIFSGDLFKMYSKYAEQRGWKIEVISASEGEHGGYKEIISRIYGDGVYSQLKFESGAHRVQRVPATESQGRIHTSACTVAVMPEADEVEGIDINPADIKVDTFRASGAGGQHVNKTDSAIRITHIPTGVVVECQDQRSQHKNRAAAMSMLKSKLLQAEIDKQQKEQSDTRKSLVGSGDRSERIRTYNYPQGRVTDHRINLTLYKLDEVMEGSLDSIIQPLVLEHQADLLATMSDE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD1_ROSS1
Sequence: MLQTQELQINIGPQHPSTHGVFRMIVTVDGETIVDLKPVFGYLHRNHEQLAEVSTYIQSMPYTDRLDYFNSMANNHALALAVEKLAGISVPQRAEYIRVLMVELTRILNHASAVGFLLNDMGAWQTPLMFGMREREKILDLFEMASGARMMCNYFRFGGVWRDLPPEFIPQLKELMQGLPSFFDEFERLLKENEILLSRTINVGVLPKEVAVSYSVTGPVLRASGIPYDVRRAEPYSVYDELDFDIPIGSVGDVYDRFLIRIEEMRQSYRILQQVIERLPDTTGGHINPAMANIGKQKALRPPPGDAYARIESPKGELGFYLVSDGSERPYRYKVRAPSFINLTPLGDMCRGHKVADVVVILGSIDIVMGEVDK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 1, NADH dehydrogenase I subunit D 1, NDH-1 subunit D 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACHB2_MOUSE
Sequence: MARCSNSMALLFSFGLLWLCSGVLGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEDFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSDVASLDDFTPSGEWDIIALPGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPTLLFLQQPRHRCARQRLRLRRRQREREGAGTLFFREGPAADPCTCFVNPASMQGLAGAFQAEPAAAGLGRSMGPCSCGLREAVDGVRFIADHMRSEDDDQSVREDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYTATTFLHSDHSAPSSK
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit beta-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-2/CHRNB2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: NDK_MACCJ
Sequence: MEKTFLMIKPDGVGRGLIGEIVKRIENKGIKVVGAKLMTVSEDLAKTHYGEHSEKPFFGELVEFITSGPVFAMVLEGDNVVEIGRTLVGKTNPAESAPGTIRGDFGMTVGKNIIHGSDSVASADKEIALWFKEEEILSYDLVTSAWVY
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM60_HUMAN
Sequence: MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALTELGYNVFFVRD
What are the official names of this protein?
Transmembrane protein 60.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GL13_ARATH
Sequence: MKYPFQCFLAKIILLALASSFVSCYDPSPLQDYCVAVPEKNGVFVNGEFCKDPKLVTSDDFFASGLNIPGNTNKRLGSFVNPANIPGLNTLGVGIARIDFAPGGLIPPHIHPRASEIILVIKGKLLVGFVSSNDYNYTLFSKILYPGDVFVHPIGLVQFHANIGKTNAVAIGAVGSQNPGYISVGDAVFGSKPPIDPKILAKAFALDINIVRYLRKVFSPQDDIVND
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 1 member 3.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RL21_ACIAC
Sequence: MYAVIKTGGKQYRVASGEKIKVEQIAADVGQEIVIDQVLAVGNGAELKVGTPLVSGATVTATVVAHGKHDKVRIFKMRRRKHYQKRQGHRQQFTELQIGAIAA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SBI_STAAR
Sequence: MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNEKDSIENRRLAQREVNKAPMDVQKHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYYNKYYQYKGLIDKTVLTTIGSGYGSYIKPLEVSKESGNLAKSYAQVRNYVTESINTGKVLYAFYQKPELVKTAIKAQETATTFKNALTGIFKSFWK
What is the function of this protein?
Plays a role in the inhibition of both the innate and adaptive immune responses.  Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH.  By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.
What are the official names of this protein?
Immunoglobulin-binding protein Sbi.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin-binding protein Sbi family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Occurs both extracellularly and associated with the cytoplasmic membrane where only the domains I and II are exposed to the extracellular media. Membrane association occurs via binding to lipoteichoic acid.
Protein: RL16_MARN8
Sequence: MLQPKRTKFRKVMKGRNTGLAQRANKVSFGEYGLKATSRGRITARQIEAARRTMTRRIKRGGKIWIRVFPDKPITGKPLEVRMGKGKGSVEYWVAEIQPGRMLYEMEGVAEEIAREAFTLAAAKLPVQTTFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PYRF_STAS1
Sequence: MKNLPIIALDFDSTEAVDQFLDQFNEPLFVKIGMELFYQTGPQLIASIKDRGHDIFLDLKLHDIPNTVGKAMEGLSKLNIDLVNVHAAGGTEMMKQALNGLQKHNPDIKLIAVTQLTSTTETMLHKEQNIQTSIEEAVLNYATLAQSSGLDGIVCSPLEAKLVKNELGNDFLKVTPGIRPKDASSDDQKRITTPEDAKELGSTHIVVGRPITKSENPVASYHKIKESWLG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: PROA_CLOTE
Sequence: MDDLNKYLINKGKKAKEASRFLSSVDSNFKNKALHKMGEDLKANMNKIIAANKIDMEKGKEKGLSKSLLDRLLIDEKRVNDMVNGLIEVAELPDPIGEVLNMWKRPNGINIGVKRVPLGVIGIIYEARPNVTVDATALCLKSGNAVILRGGSEAINTNKAIGKILENSAIESGLPEGTIQLIETTDREIVNKMLKLNEYIDVLIPRGGRGLIDNVVKNSTVPVIQTGVGLCHVYVDGSANLKMAQDIIVNAKTQRPGVCNALETLLVHKDVANSFLPEIVSEISKYGVESKLCEKSFEVVKGSIKDAKVLSLISEATEEDWDTEYLDLILSIKIVNSLDEALNHIYDHGTKHSEAIITENYTNSQRFLNEVDAAAVYVNASTRFTDGSQFGFGAEIGISTQKLHARGPMGLTQLTTTKYIIYGNGQIR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGT_ECO7I
Sequence: MQIKRSIEKIPGGMMLVPLFLGALCHTFSPEAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACSF_GLOVI
Sequence: MVDALREANTASQSERRETLLTPRFYTTDFEALAKLDISAMEADFEALLAEFQADYNREHFQRDAGFVEQAHQIDPQWRALMLEFLERSCTSEFSGFLLYKEISRRLKAANPLLAECFKAMSRDEARHAGFLNKAMGDYDLGLDLSNLAKQKKYTFFKPKFIFYATYLSEKIGYWRYIAIFRHLERHPENRIHPLFNYFKNWCQDENRHGDFFGLILKSQPQLLKGPINRLWVRFFLLSFCLTMYLNDRKPHNLYSALGLDASHYAMEVLRQTNLDSGKVFPLILDLDNPRFQRHLDRCADLNLQLEALSGKSPLARLPVIAALAGTIAQLFLLKPVAPPAPEMVR
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: IFI2_MOUSE
Sequence: MSNRNLRSSTNSEFSEGQHQTPSSDSSGHGEDQPQASPGPNKKSHTPKKNISKGAVLHEKPMTVMVLTATEPFNYKEGKENMFHATVATESQYYRVKVFNMDLKEKFTENKFITISKYFNSSGILEINETATVSEAAPNQIIEVPKNIIRSAKETLKISKIKELDSGTLIYGVFAVEKKKVNDKSITFKIKDNEDNIKVVWDKKQHNINYEKGDKLQLFSFHLRKGNGKPILHSGNHSFIKGEKLLKESFEGDGYHKGPKQVVALKATKLFTYDSIKSKKMFHATVATDTEFFRVMVFEENLEKKFIPGNTIALSDYFGMYGSLAIHEYSSVSEVKSQNKEDSSSSDERLIEHLKICDLHLQTKERLVDGEFKVYRKSTGNNCICYGIWDDTGAMKVVVSGQLTSVNCEIGNTIRLVCFELTSNADEWFLRSTRYSYMEVIMPEK
What is the function of this protein?
DNA-binding protein involved in innate immune response and has anti-inflammatory activity (PubMed:19131592, PubMed:23850291, PubMed:23567559).  Inhibits caspase activation in response to cytosolic DNA by preventing activation of the AIM2 inflammasome, probably by sequestering cytoplasmic DNA and preventing its being bound by AIM2 (PubMed:19131592, PubMed:23850291, PubMed:23567559).  Also inhibits activation of the AIM2 inflammasome via a direct interaction with AIM2, which prevents the interaction between AIM2 and PYCARD and formation of the AIM2 inflammasome (PubMed:23850291).  Binds double-stranded DNA (dsDNA) in the cytosol (PubMed:19131592, PubMed:23850291, PubMed:23567559, PubMed:24419611).  Has anti-apoptotic effects due to inhibition of the transcriptional activity of TP53/p53 (PubMed:16670293).  Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin (PubMed:8524315).
What are the official names of this protein?
Interferon-activable protein 202, Ifi-202, Interferon-inducible protein p202, Lupus susceptibility protein p202.
What is the protein family that this protein belongs to?
Belongs to the HIN-200 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Accumulates first in the cytoplasm, and is translocated to the nucleus after a delay, where it is primarily chromatin-associated.
Protein: GDPP_BACSU
Sequence: MPSFYEKPLFRYPIYALIALSIITILISFYFNWILGTVEVLLLAVILFFIKRADSLIRQEIDAYISTLSYRLKKVGEEALMEMPIGIMLFNDQYYIEWANPFLSSCFNESTLVGRSLYDTCESVVPLIKQEVESETVTLNDRKFRVVIKRDERLLYFFDVTEQIQIEKLYENERTVLAYIFLDNYDDVTQGLDDQTRSTMNSQVTSLLNAWAQEYGIFLKRTSSERFIAVLNEHILTELENSKFSILDEVREKTSFDGVALTLSVGVGASVSSLKELGDLAQSSLDLALGRGGDQVAIKLPNGKVKFYGGKTNPMEKRTRVRARVISHALKEIVTESSNVIIMGHKFPDMDSIGAAIGILKVAQANNKDGFIVIDPNQIGSSVQRLIGEIKKYEELWSRFITPEEAMEISNDDTLLVIVDTHKPSLVMEERLVNKIEHIVVIDHHRRGEEFIRDPLLVYMEPYASSTAELVTELLEYQPKRLKINMIEATALLAGIIVDTKSFSLRTGSRTFDAASYLRAKGADTVLVQKFLKETVDSYIKRAKLIQHTVLYKDNIAIASLPENEEEYFDQVLIAQAADSLLSMSEVEASFAVARRDEQTVCISARSLGEVNVQIIMEALEGGGHLTNAATQLSGISVSEALERLKHAIDEYFEGGVQR
What is the function of this protein?
Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP) and to a much lesser extent against cyclic-di-GMP (c-di-GMP) in the DHH/DHHA1 domains (PubMed:19901023, PubMed:21257773).  Also has ATPase activity, probably via the GGDEF domain (PubMed:19901023, PubMed:21257773).  Overexpression leads to increased sensitivity to methyl methanesulfonate (MMS) and H(2)O(2) (PubMed:25616256).  Overexpression leads to extreme sensitivity to the beta-lactam antibiotic cefuroxime (CEF), probably dependent on PDE activity (PubMed:22211522).  May monitor cellular heme or NO levels (PubMed:21257773).  In B. subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess (PubMed:26240071).
What are the official names of this protein?
Cyclic-di-AMP phosphodiesterase GdpP, c-di-AMP phosphodiesterase YybT, Cyclic-di-AMP hydrolase GdpP, Cyclic-di-AMP phosphodiesterase YybT.
What is the protein family that this protein belongs to?
Belongs to the GdpP/PdeA phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=After 3.5 hours of sporulation is present in a punctate pattern associated with the cell membrane. Does not co- localize with c-di-AMP synthase DisA.
Protein: NRDR_GLUDA
Sequence: MRCPFCGHEDTQVKDSRPHEDGAAIRRRRICAACSQRFTTIERVQLRDLYVVKADDRRVPFERDKLARSVRIALRKRPVDEERIERIVNGLVRQLEASGETDIPSRDIGKLVMGTLREVDIVAYIRFASVHWDFRETKDFAAILQSIPGTADGDVPVVPGDAAAAIAAESGPGGVKRR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: HRCA_PARMW
Sequence: MKPLSARQQQVLQATVHHYVDTMEPVGSRTLVQRFGIPASSATVRSAMGALEKRGLLTQPHTSAGRIPSALGYRCYVDDLLPEPGVAVQHLERELTGLSLRWAALDDLLQQLARRLTDFTGLMSLITRPQQPRAQLEAIRLVQSGDRLLVMLVEDSGRASHLNLRLPPGASDELTAIERWTDQQLEDGSINWRSLPPQLQRSGDVLRSALDHPSMSPETPLVVHGLSRLVAEPEFHSTAELRPLLELIDDQPCAVVSATDQPGVWIGEEHPQKALQACSVVQAPYRCGQEGVGQVALVGPMRMAYATAHAAVQRVARHLDLLLN
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SYT_CHLCH
Sequence: MSDHKESTGAIALTLPDRSVRNVAMGSTGYDVALSIGRKLAQDALAIKLNGVVCDLNTLINSDAAIEIITFTSPEGPEIFWHSSSHLMAQAIEELFAGSKFGAGPAIEQGFYYDVSSEHRFREEDLRAIEARMLEISKRDSSVQRQEMSREEAIAFFTSVRNDPYKVEILTETLKNVERVSLYHQGDFTDLCTGPHLPSTGKIKAVLLTNISASYWRGDSNREQMQRIYGITFPSEKLLKEHVARIEEAKRRDHRKLGAELELFLLSPEVGSGLPMWLPKGAIIRSELESFLREEQRKRGYVPVYTPHIGNIELYKRSGHYPYYSDSQFPPLTYHDEDGKQEQYLLKPMNCPHHHLIYSSKMRSYRDLPLRFTEFGTVYRHEQSGELNGLARARGFTQDDSHIYCRPDQLVDEICSAIELTQFVFKTLGFAEVQTRLSLHDPANQAKYGGTAEVWEQAEKDVQEAAERMGVDYFIGIGEASFYGPKIDFIVRDAIGRKWQLGTVQVDYVMPERFDLTYVGSDGQKHRPVVIHRAPFGSMERFIGLLIEHTAGNFPLWLAPVQVAVLPIAEENHDYATTVYRRLLAAGIRAELDTRSEKINRKIRDAEMSKTPCMLVIGQKEQANGEVSLRRHRQGDAGRFATDELIETLKQEIANRQ
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_LEVBA
Sequence: MKTKEINELTTAEMLDKEKSYKDELFNLRFQLATGQLENTARLKQVRKNIARLKTALRQQELNK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL10_ZYMMO
Sequence: MERAQKVELVAGLKSAFAEAGVIVVTRNLGLTVAQSTVLRSKMREAGASFKVAKNKLTRIAVEGTPQAPLSDLLTGPTAIATSADPVAAAKVAVEFAKTNKKLEIVGAVMGTTLLDIAGVQALAELPSLDELRGKIVGLISAPATKIAQTIQAPAGQLARVFGAYAAKDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: V07K_STMV
Sequence: MLLGDIGGKHIAFFYKRPSVAIITWRPILGFSCCFQLWGEVRLNQTVNRRVTIRMLLL
What are the official names of this protein?
6.8 kDa protein.
Protein: UPAR_MOUSE
Sequence: MGLPRRLLLLLLLATTCVPASQGLQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPRPGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSLKDEDYTRGCGSLPGCPGTAGFHSNQTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCATASWCQGSHVADSFPTHLNVSVSCCHGSGCNSPTGGAPRPGPAQLSLIASLLLTLGLWGVLLWT
What is the function of this protein?
Acts as a receptor for urokinase plasminogen activator.  Plays a role in localizing and promoting plasmin formation.  Mediates the proteolysis-independent signal transduction activation effects of U-PA.
What are the official names of this protein?
Urokinase plasminogen activator surface receptor, U-PAR, uPAR.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: G3P_BPPHL
Sequence: MSPSLFLGWGDDYFVVLWIHGRAVRLGRRQGVGRVIRVSLAMLILLALTFSPIVHATCVQTEPSTSANNGSWACSDQGEAFAKASSMGVPADLSVCRMKSIRAVSSGPGVFSQRMTYPGDTCGIGYDLDIGTGNATYPDTATCAKRPSQSGWTNPTAPTPSDVCNDGCYYTYAVDAGGPKGYTYVPSGATCTTDDAAPPIDDGGDGDDDGGGDGGGDGGGDGGGDGGGDGGGDGGGDGGGDGGGDGGGDGDGGGDGDGDGDGDGDGEEGGEGAPMSELYKKSGKTVESVLSKFNTQVRGTPMVAGIGDFMKVPSGGSCPVFSLGASKWWDAMTINFHCGGDFLAFLRAAGWVILAIAAYAAIRIAVT
What is the function of this protein?
Plays essential roles both in the penetration of the viral genome into the bacterial host via pilus retraction and in the extrusion process.  During the initial step of infection, G3P mediates adsorption of the phage to its primary receptor, the tip of host F-pilus.  Subsequent interaction with the host entry receptor tolA induces penetration of the viral DNA into the host cytoplasm.  In the extrusion process, G3P mediates the release of the membrane-anchored virion from the cell via its C-terminal domain (By similarity).
What are the official names of this protein?
Attachment protein G3P, Gene 3 protein, G3P, Minor coat protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus G3P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass membrane protein. Note=Prior to assembly, G3P is found associated with the bacterial host inner membrane. There are about five copies of this protein per mature phage that are located on the head side of the filamentous virion.
Protein: RNZ_ARCFU
Sequence: MLFKITFLGTSGTIPSVERNSPAIFVQFGGQRMLFDCGEGTQRQMMIAKTGFRNLDNIFITHLHTDHFIGLFGLIETMSLNERSRELNVYSPRAEVLRALFEAFGYDQLNYDIRVRELKDGEEVKFDGFKVVAFRTEHIVKSVGYAIIENDRRGKFNREKAEKELGIPPGPLYAKLARGESIVWKGRTITPDMVLGEKRRGRKVVYTGDSRPTKRTVEIARNADILIHDASFKEELKDWAIESGHSTAKEAAEVAREANVKKLILTHISTRYSKDASPLLEEAKKVFENTIIAEDFMSLEVTFDES
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RL18_DINSH
Sequence: MANSKRDLFLKRRLRVRNKLKKMADGRPRLSVHRSGKNISVQLIDDVQGRTLAAASSLEKDLGIVGKNNVEASAKVGAAIAERAKKAGIEECYFDRGGFLFHGKVKALADAAREGGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MDTC_SALG2
Sequence: MRFFALFIYRPVATILIAAAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILEFNFDRDINGAARDVQAAINAAQSLLPGGMPSRPTYRKANPSDAPIMILTLTSESWSQGKLYDFASTQLAQTIAQIDGVGDIDVGGSSLPAVRVGLNPQALFNQGVSLDEVREAIDSANVRRPQGAIEDSVHRWQIQTNDELKTAAEYQPLIIHYNNGAAVRLGDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDGIRAKLPELRAMIPAAIDLQIAQDRSPTIRASLQEVEETLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVISMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLVVSLTLTPMMCGWMLKSSKPRTQPRKRGVGRLLVALQQGYGTSLKWVLNHTRLVGVVFLGTVALNIWLYIAIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVNNVTGFTGGSRVNSGMMFITLKPRGERKETAQQIIDRLRVKLAKEPGARLFLMAVQDIRVGGRQANASYQYTLLSDSLAALREWEPKIRKALSALPQLADVNSDQQDNGAEMNLIYDRDTMSRLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYSQDISALEKMFVINRDGKAIPLSYFAQWRPANAPLSVNHQGLSAASTIAFNLPTGTSLSQATEAINRTMTQLGVPSTVRGSFSGTAQVFQQTMNSQLILIVAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRSGGLTPAQAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKNSKPVVEI
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPB_BIFA0
Sequence: MAENQANAAADEAAEPIVGHVTRIQGSVIDVEFPVGHMPDIYNALTVEIKQMGQQEEGEVKDSVITLEVEQHLGDSTARCVALKSTDGLVRGAIVHDTGGPIEVPVGDVTKGHVFDVSGHILNKKPGEKIVIKERWPIHRNPPAFDQLESKTQMFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMIQRVAQNHGGVSVFAGVGERTREGNDLIGEMDEAGVLEKTALVFGQMDEQPGTRLRVPLTALTMAEYFRDVQNQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPNLADEMGSLQERITSTRGHSITSLQAIYVPADDYTDPAPATTFAHLDATTELSRDIASRGIYPAVDPLASTSRILDPRYVGQAHYDCANRVKAILQRNKELQDIIALIGIDELGEEDKTTVNRARKIEQFLGQNFYVAEKFTGVPGSYVPAEETIEAFTRICDGVYDNVPEQAFSGIGGIEDLEKKWHKMQKEYGD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.