PharMolix/UniProtQA huggingface dataset:
Protein: RHAM_SHIB3
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQG
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GC_EHV1D
Sequence: MWLPNLVRFVAVAYLICAGAILTYASGASASSSQSTPATPTHTTPNLTTAHGAGSDNTTNANGTESTHSHETTITCTKSLISVPYYKSVDMNCTTSVGVNYSEYRLEIYLNQRTPFSGTPPGDEENYINHNATKDQTLLLFSTAERKKSRRGGQLGVIPDRLPKRQLFNLPLHTEGGTKFPLTIKSVDWRTAGIYVWSLYAKNGTLVNSTSVTVSTYNAPLLDLSVHPSLKGENYRATCVVASYFPHSSVKLRWYKNAREVDFTKYVTNASSVWVDGLITRISTVSIPVDPEEEYTPSLRCSIDWYRDEVSFARIAKAGTPSVFVAPTVSVSVEDGDAVCTAKCVPSTGVFVSWSVNDHLPGVPSQDMTTGVCPSHSGLVNMQSRRPLSEENGEREYSCIIEGYPDGLPMFSDTVVYDASPIVEDRPVLTSIIAVTCGAAALALVVLITAVCFYCSKPSQAPYKKSDF
What is the function of this protein?
Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Also plays a role in host immune evasion by inhibiting the host complement cascade activation (By similarity).
What are the official names of this protein?
Envelope glycoprotein C, gC, Glycoprotein 13.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein C family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: GLTA_WHEAT
Sequence: MKTFLVFALLALAAASAVAQISQQQQAPPFSQQQQPPFSQQQQPPFSQQQQSPFSQQQQQPPFAQQQQPPFSQQPPISQQQQPPFSQQQQPQFSQQQQPPYSQQQQPPYSQQQQPPFSQQQQPPFSQQQQQPPFTQQQQQQQQQQPFTQQQQPPFSQQPPISQQQQPPFLQQQRPPFSRQQQIPVIHPSVLQQLNPCKVFLQQQCIPVAMQRCLARSQMLQQSICHVMQQQCCQQLRQIPEQSRHESIRAIIYSIILQQQQQQQQQQQQQQGQSIIQYQQQQPQQLGQCVSQPLQQLQQQLGQQPQQQQLAHQIAQLEVMTSIALRTLPTMCNVNVPLYETTTSVPLGVGIGVGVY
What is the function of this protein?
Glutenins are high-molecular weight seed storage proteins of wheat endosperm.  Thought to be responsible for the visco-elastic property of wheat dough.
What are the official names of this protein?
Glutenin, low molecular weight subunit.
What is the protein family that this protein belongs to?
Belongs to the gliadin/glutenin family.
Protein: UCKL1_HUMAN
Sequence: MAAPPARADADPSPTSPPTARDTPGRQAEKSETACEDRSNAESLDRLLPPVGTGRSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTEQQQEQAAHNNFNFDHPDAFDFDLIISTLKKLKQGKSVKVPIYDFTTHSRKKDWKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPSFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHSQLEERELSVRAALASAHQCHPLPRTLSVLKSTPQVRGMHTIIRDKETSRDEFIFYSKRLMRLLIEHALSFLPFQDCVVQTPQGQDYAGKCYAGKQITGVSILRAGETMEPALRAVCKDVRIGTILIQTNQLTGEPELHYLRLPKDISDDHVILMDCTVSTGAAAMMAVRVLLDHDVPEDKIFLLSLLMAEMGVHSVAYAFPRVRIITTAVDKRVNDLFRIIPGIGNFGDRYFGTDAVPDGSDEEEVAYTG
What is the function of this protein?
May contribute to UTP accumulation needed for blast transformation and proliferation.
What are the official names of this protein?
Uridine-cytidine kinase-like 1.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.
Protein: TM129_CHICK
Sequence: MESPAVTFTLAYLVFAVCFVFPPDEVRSAGLTVQSLLAAWLGSEDAAFVQYHLRRSTGTLLAHSLLPLGYYFGMCFAAPEKHLCFFYLASKEWKTFFFFAVLLPAVSSTMAYYWSRKGWNNHPLARTLAVYALPQSGWRAVASSINTEFRRIDKFATGAPGARVIVTDTWVIKVTTYCLHVAQQQDIHLTVTDSRQHELTPDSNMPVQFLTIRVASVNPYVKAFDIRLNSAEYGELREKLRAPISNAANVVIHQSLSDLFLETFTSLVEMNQTYSVPSTQELEPCIGCMQTIANIKLIKNCQEPNEGECQQCYCRPMWCLTCMGKWFASRQDQQHPETWLSSHVPCPTCRAKFCILDVCIIR
What are the official names of this protein?
Transmembrane protein 129.
What is the protein family that this protein belongs to?
Belongs to the TMEM129 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y9487_DICDI
Sequence: MSKRNSTKNDIKLSDVGVAQWMDYQIILQEWKIGKLSSEIKNSIVKDMSSLSEFRGQSINANELESMIGDWSIYPITNKFKIIALWKIIENHRNKHNLGYILKSNVLEKTNKSKQNNNGFNGHKGNFSENEIRKTNNYRIIKKQKIEFEKNNKNTIITRKNNNNNNSNNNNNNNNNYNQKSNTTMDNNYSDDDYQNEQNEFEEEDYDSNDDENDSHDENENFNIIKPKTTNQLKRKVSSSFTNNNYHVNNNNNNNDNINNFNSNSNSNTSNNNNNNNSDNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNYINNNNNDSWNNQFQNQLMYCNNYQAQYQQLHPNHYQLQYQQQQQNINNNINANNNNNNNNNNNNNNNLNDSTPNNQTNNDLKSSNHSNYDFNYNTNERLSHSPIQTHSSSNNSTPSNQSPTFPSNYISQNANINYNPNQGSMFYPPQQFYVESMFYQQQLQQQQQQQQQIAQQPVSQQNNNVETNQDNVQQQ
What are the official names of this protein?
Putative uncharacterized protein DDB_G0267716.
Protein: MCPB_ARTBC
Sequence: MVAYRLLALISLGLGSHCASALQYGYNQLSTHKDSAVVAGAFPAINGTHLQSPAFTSPGTVPRGFSDGTSGPTRDETMEGFMRRLARSNSWMAYHEADFKSEEGRKFPYMYLSASNSSVENPSSHKLRVWLQGGVHGNEPAGDQSMLALLGDLAANQKWAAKLLEKMDILVLPRYNPDGVFYFQRYLATNFDPNRDHVKLARQQTRDIKELFTRFSPHIATDMHEFTAGRTFGPKKDIIYAADALFSAAKNLNIDEGIRQLSEKLFAKRMGKDIEAAGLRWDPYITQGESSSSKLLLLEAGTDAKIGRNAMGLSQCVVFLCETRGIGIADQHFERRTLSGLVMAKSILQTAVDNFDEVYNTIERGIRRFTNSRNDIVLTDKSPIMERTFGMLNITDASLFDYPIDFATTTPAEAVLTRSRPRAYLIPPSWPDIVKRLEVFGVKADKLPYSYVGPVEALNVTSVTFDKEYYEGVVTTTVQTKLVERNIRLPAGSYLVKTNQKNAALAFVALEVRTKDLLPVLIMDVY
What is the function of this protein?
Extracellular metalloprotease that contributes to pathogenicity.
What are the official names of this protein?
Probable carboxypeptidase 2, Carboxypeptidase M14B, Carboxypeptidase MCPB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MED29_DICDI
Sequence: MNLDSLSKIIKNKIQNVLYPTSKALLSSDDPSKRAETCYDLSQKIEEFELVCDELYGIIEIHKQNVIFSNINNGTHISKENNPEVLFNSLVSRLSTLRQTKSTMDSFAKEISIVQPIDNKANTNNNNNNNNNNNNNNNNNNNNNNNTNTNTNNTNNTNNTTNTNNTNNNNNNNYNNNNNNNNNNNNNNNNNNNNNNNNSINNSINNNSNNKVGSNDNPSTAPITENNTENNAGNTNNTNNNNNNNNNNNNNNNNNNNNNNNNTNQVAESSNISSNTTPPETTNIVNDPNSVSGGNLTNTEAPMEISDNSEIQHPQQEQQQQQQQQQQQQQQQQQQQQQPQEQIPQQQQPQLPMQQEQIQQLPQQQTPPSQQQPQQTPPLPQQFQQPLVNVNQITSPTLENQSISGNNNNNNDGQTISPQQQQEQLQLQMQQLQQLQMQQQQMNFNPTEPINTNFYNIDLQQPIQQQTLNNNNNNINSLENQINTNLGGNTFNTGTTPPLQQQPQPQQQQQINNPEINQIDDDNTMKETIDVDKIIEESNNVNNNVNNRQVIDLE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Putative mediator of RNA polymerase II transcription subunit 29, Putative mediator complex subunit 2, Putative mediator complex subunit 29, Putative mediator of RNA polymerase II transcription subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 29 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCF2B_ATRBE
Sequence: MRGHQFKSWILELREILREIKNSHHFLDSWTQFTSVGSFIHIFFHQERFLKLFDPRIWSILLSRNSQGSTSNRYFTIKGVILFVVAVLIYRINNRNMVERKNLYLIGLLPIPMNSIGPRNDTLEESVGSSNINRLIVSLLYLPKGKKISESCFLNPKESTWVLPITKKCSMPESNWGSRWWRNWIGKKRDSSCKISNETVAGIEILFKEKDLKYLEFLFVYYMDDPIRKDHDWELFDRLSLRKSRNRINLNSGPLFEILVKHWISYLMSAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFRQDLFVSWGKNPPESDFLRNVSRENWIWLDNVWLVNKDRFFSKVQNVSSNIQYDSTRSSFVQVTDSSQLKGSSDQSRDHLDSISNEDSEYHTLINQREIQQRKERSILWDPSFLQMERKEIESGRFPKCLSGYSSMSRLFTEREKQMINHLFPEEIEEFLGNPTRSVRSFFSDRWSELHLGSNPTERSTRDQKLLKKQQDLSFVPSRRSENKEMVNIFKIITYLQNTVSIHPISSDPGCDMVPKDEPDMDSSNKISFLNKNPFFDLFHLFHDRNRGGYTLHYDFESEERFQEMADLFTLSITEPDLVYHKGFAFSIDSCGLDQKQFLNEARDESKKKSLLVLPPIFYEENESFSRRIRKKWVRISCGNDLEDPKPKIVVFASNNIMEAVTQYRLIRNLIQIQYSTYGYIRNVLNRFFLMNRSDRNFEYGIQRDQIGKDTLNHRTIMKYTINQYLSNLKKSQKKWFEPLILISRTERSMNRDPDAYRYKWSNGSKNFQEHLEQSVSEQKSRFQVVFDRLRINQYSIDWSEVIDKKDLSKPLRFFLSKPLRFFLSKSLLFLSKLLFFLSNSLPFFCVSFGNIPIHRSEIYIYELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHDTSQKSKFLINGGTISPFLFNKIPKWMIDSFHTRNNRRKSFDNPDSNFSMIFHDQDNWLNPVKPFHRSSLISSFYKANRLRFLNNPHHFCFYWNTRFPFSVEKARINNSYFTYGQFLNILFIRNKIFSLCVGNKKHAFWGRDTISPIESQVSNIFIPNDFPQSGDETYNLYKSFHFPSRSDPFVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDMNLSDSEGKNLHQYLNFNSNMGLIHTPCSEKDLSSEKRKKRSLCLKKCVEKGQMYRTFQRDSAFSTLSKWNLFQTYMPWFLTSTGYKYLNLIFLDTFSDLLPILSSSQKFVSIFPDIMHGSGISWRILQKKLCLPQWNLISEISEISSKCLHNLLLSEEMIHRNNESPLISTHLRSPNAREFLYSILFLLLVAGYLVRTHLLFVSRASSELQTEFEKVKSLMIPSSMIELRKLLDRYPTSEPNSFWLKNLFLVALEQLGDSLEEIRGSASGGNMLGPAYGVKSIRSKKKDWNINLIEIIDLIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVNGDWIDDKIESWVANSDSIADEEREFLVQFSTLTTENRIDQILLSLTHSDHLSKNDSGYQMIEQPGAIYLRYLVDIHKKHLMNYEFNPSCLAERRIFLAHYQTITYSQTSCGENSFHFPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFLLDEIDIDDSDDIDDSDNLDASDDIGRDLDTELELLTRMNGLTMDMMPEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNDLSLGLLVNHLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFGSITMGSNARDLVALTNEVLSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLLSNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKRLTILLYLLSCSAGSVAQDLWSLSGPDEKNGITSYGLVENDSDLVHGLLEVEGALVGSSRTEKDCSQFDNDRVTLLLRPEPRNPLDMMQKGSCSILDQRFLYEKYESEFEEGEGEGALDPQEDLFNHIVWAPRIWRPWGFLFDCIERPNELGFPYWSRSFRGKRIIYDEEDELQENDSGFLQSGTMQYQTRDRSSKEQGLFRISQFIWDPADPLFFLFKDQPPGSVFSHRELFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLINRQRWLRTNSSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMTKTLLRKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2 B.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: BPPEA_BOTJA
Sequence: QWAQWPRPTPQIPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent.  Bradykinin-potentiating peptide 11a-F has much lower activity than BPP-11a.
What are the official names of this protein?
Bradykinin-potentiating peptide 14a, BPP-14a.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCN3B_MOUSE
Sequence: MPAFNRLLPLASLVLIYWVRVCFPVCVEVPSETEAVQGNSMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLFIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSVVPVEE
What is the function of this protein?
Modulates channel gating kinetics.  Causes unique persistent sodium currents.  Inactivates the sodium channel opening more slowly than the subunit beta-1.  Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity).
What are the official names of this protein?
Sodium channel subunit beta-3.
What is the protein family that this protein belongs to?
Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GPM6A_RAT
Sequence: MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFEMARTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGRCVSAWFIMLTYLFMLAWLGVTAFTSLPVYMYFNVWTICRNTTLVEGANLCLDLRQFGIVTIGEEKKICTVSENFLRMCESTELNMTFHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRSKERLNAYT
What is the function of this protein?
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells (By similarity).  Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation.  Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways.  May be involved in neuronal NGF-dependent Ca(2+) influx.  May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
What are the official names of this protein?
Neuronal membrane glycoprotein M6-a, M6a.
What is the protein family that this protein belongs to?
Belongs to the myelin proteolipid protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, growth cone. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, neuron projection. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons (PubMed:21426347). Localized to plasma membrane of cell bodies and neurites of hippocampal neurons (PubMed:16286650). Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons (PubMed:16286650). Localized to the growth cone edge membrane of elongating axons (By similarity).
Protein: DEOD_STRPS
Sequence: MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRNMFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRELVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFYSNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEERQNTFTDMMKVGLETLIAE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: RL361_KINRD
Sequence: MKVRASLKSLKQKEGSIVVRRRGKTYVLNKRNPRWKARQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: GCH1_CAUVC
Sequence: MDALTRERTLIGSDDTTGLDLEPVQRPSKDEAMAAVRTLLAWAGDNPEREGLIDTPKRVVEAFDEWFAGYHGDPAKELSRTFEDVQGYDDMVMLRGIDVQSHCEHHMAPFLGKAWIAYMPTGKVVGLSKLARLVEIFAKRLQTQETMTMQIADAIEDHLSAAGVAVLIDAEHQCMSTRGVHHHDVSTITTQFRGVFKTDKVLQQRFMDLVKK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GUAC_YERE8
Sequence: MRIEEGLKLGFKDVLIRPKRSTLKSRSEVELERQFTFKHSGWNWSGVPIIAANMDTVGTFRMAEVLASFDVLTAVHKHYTVEQWGEFVKRVPESVLRHVMVSTGTSSADFDKMKQILALSPALKFICIDVANGYSEHFVSFLQKAREACPDKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGQIVSDGGCSVPGDVAKAFGGGADFVMLGGMLAGHDECEGRVVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGSVDNTVRDIMGGLRSACTYVGASHLKELTKRTTFIRVAEQENRVFGSN
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: SIM24_HUMAN
Sequence: METLGALLVLEFLLLSPVEAQQATEHRLKPWLVGLAAVVGFLFIVYLVLLANRLWCSKARAEDEEETTFRMESNLYQDQSEDKREKKEAKEKEEKRKKEKKTAKEGESNLGLDLEEKEPGDHERAKSTVM
What are the official names of this protein?
Small integral membrane protein 24.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RLMG_SHESA
Sequence: MTTQFSVAGIELELFRYPASQESNLQAWDAADEHLINTLVEGGQTAVPTAIINDSFGALSCALSRLNPDWPLNVETDARTSFLGAEQNHHRNQLPMDNLTRFTSRDALPCDLALVLMKLPKNLTYFAHQLMRLSQVLPAGCKVLVGAKAKSINASLLEVFATHLGPASASLAWKKTRVITCISDGKPRALPKEVTWDIPEFNLHISNLSNVFAANKLDIGARIMLDNLPQGDFKTIVDLGCGNGVLGLRAAQLYPNADIHFIDDSEMAVASAKANWANNQLPAEKGHFHWDDCMTHLPDGVEPDLVLCNPPFHQGEAITDHIAWQMFLDARRRLKNGGILHIVGNRHLAYHVKLQRLFKNCTTVASNGKFVILQAQK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_BORBU
Sequence: MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGATLLRNNEVWTEKIVYFGPMGCRTGFYLIIFGDYESKDLVDLVSWLFSEIVNFSEPIPGASDKECGNYKEHNLDMAKYESSKYLQILNNIKEENLKYP
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: LGT_PSEAE
Sequence: MLTYPQIDPVALAIGPLKIHWYGLMYLIGIGGAWLLASRRMKRFDPTWTKERLSDLVFWVACGVILGGRLGYVLFYNLDEYIANPTLIFEVWKGGMSFHGGLLGVMLAVWWFGKRHGKSFFQLMDFIAPLVPIGLGAGRIGNFINSELWGKVSDVPWAMVFPNGGPLPRHPSQLYQFALEGVALFVILWLFTRKPRPTASVSGLFVLCYGIFRFVVEFVRVPDAQLGYLAWGWLTMGQVLCVPMVLAGIALMVWAYRRDAAQPKAA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LYSX_DROME
Sequence: MRALLGICVLALVTPAVLGRTMDRCSLAREMANMGVSRDQLSKWACIAEHESSYRTGVVGPPNTDGSNDYGIFQINDMYWCQPSSGKFSHNGCDVSCNALLTDDIKSSVRCALKVLGQQGWSAWSTWHYCSGYLPPIDDCFV
What is the function of this protein?
Unlikely to play an active role in the humoral immune defense.  May have a function in the digestion of bacteria in the food.  May be involved in the clearance of bacteria from the larval gut before metamorphosis.
What are the official names of this protein?
Lysozyme X, 1,4-beta-N-acetylmuramidase X.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: MRAY_STRSV
Sequence: MLIALIAGIVTFILTIIGIPAFIRFYHKARITGQQMHEDVKQHQAKAGTPTMGGTVFLLTSVLASFVIGLFSHQLSNGLIMILFILVLYGVVGFLDDFLKVFRKINEGLNPKQKLFLQLVGGVVFYFFYNQHGAGDQLNIFTVPVQLGFLYVFFVLFWLIGFSNAVNLTDGIDGLASISVVISLVAYAVIAVEQKRFDILIVIISMIGGLLGFFVFNHKPAKIFMGDVGSLALGGMLAAISISLHQEWTLLLIGIVYVFETTSVMMQVTYFKLTGGKRIFRMTPVHHHFELGGLTGHGKEWSEWKVDFFFWGIGIVGSLLTLAILYL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BL1S5_NEMVE
Sequence: MAGEKMVRDISGVYARLFDHRAVLQAECKYMLREFEGKRNDRELERLRESEQKIRQVQEEIPKCITESVKLKDLLEELKVAREKCHEILVKEEQDLFKERREEIFIESKKNWETFIGEIAEEEKRIEEEFEQSAEKLRARYGVQLVRNPKEPDDKGELQPQEIA
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).  May play a role in intracellular vesicle trafficking (By similarity).
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 5, BLOC-1 subunit 5, Protein Muted homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S5 family.
Protein: TRM61_SCHPO
Sequence: MVFADYKQRVENGDLAVAWIGRNKLIPLHIEAEKTFHNQYGAFPHSEMIGKRYGEQIASTAKQGFIYLLQPTPELWTLALPHRTQIVYTPDIALIHQKLRITYGTRVIEAGTGSASMSHAISRTVGPLGRLFTFEYHATRYQTALQEFREHEMLIDVGGNTHLTHRDVCKDGFLDTEVKVDAIFLDLPAPWEAIPHLSNHVNHDKSTRICCFSPCIEQIQHSAEALRELGWCDIEMIEVDYKQWAARKSRIVHIDEAIDRLKEVKRRRIEGFERRKMRREQNLSSDAKVEDQDNDSMLGENKSSVSTETALKPVTNKRIREGDGNYEWTDVARVDSNLKSHTSYLLFAVHLPSQLDKQNQETGP
What is the function of this protein?
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit trm61, tRNA(m1A58)-methyltransferase subunit trm61, tRNA(m1A58)MTase subunit trm61.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DIOA3_DIOJA
Sequence: MSSSTLLHLLLLSSLLFSCLSCLTNVEDEFSYIEGNPNGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNYRAVDARLRNSGHDVLVDFKGNAGSLSINRVEYQLKRIHFHSPSEHEMNGERFDLEAQLVHESQDQKRAVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEINAGVVDPNQLQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAVNENAINNARPLQPTNFRSVFYFEQLKSKLGVI
What is the function of this protein?
Storage protein of tuber.  Involved in protection against oxidative stress (Probable).  Has carbonate dehydratase, trypsin inhibitor, dehydroascorbate (DHA) reductase and monodehydroascorbate (MDA) reductase activities (PubMed:22195572).  Catalyzes the reactions of carbonate dehydratase and DHA reductase independently of zinc and glutathione (GSH).  The coupled reaction is capable of recycling a plant antioxidant ascorbate using ubiquitous compounds H(2)O and CO(2) (PubMed:25747844).  Exhibits antioxidant activity.  Able to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.  Exhibits immunomodulatory activity.  Activates Toll-like receptor 4 signaling pathways by up-regulating the gene expression of pro-inflammatory cytokines, such as tumor necrosis factor alpha, interleukin-1 beta and interleukin-6, and chemokines RANTES and MCP-1, in mouse RAW 264. 7 macrophages.  Stimulates the phagocytosis of E. coli by the LPS-treated mouse macrophages (PubMed:22796748).
What are the official names of this protein?
Dioscorin dioA3, Dj-dio5, Dj-dioA3, Tuber storage protein dioA3.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.