PharMolix/UniProtQA huggingface dataset:
Protein: PE2R2_HUMAN
Sequence: MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
What is the function of this protein?
Receptor for prostaglandin E2 (PGE2).  The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase.  The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
What are the official names of this protein?
Prostaglandin E2 receptor EP2 subtype, PGE receptor EP2 subtype, PGE2 receptor EP2 subtype, Prostanoid EP2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GSA_COXB1
Sequence: MVDHSAALFNKAQNYMPGGVNSPVRAFGAVGGVPRFIKKASGPYLIDVDEKKYIDYVGSWGPMILGHAHPAVIQAAQEAVQNGLSFGAPCENEIKLAALIGEFMPSIEKVRMVNSGTEATMSALRLARGVTGRSKIIKFEGCYHGHADCLLVNAGSGALTFGMPSSPGVPLGTVQDTLTATFNDLDSVAALFEKYSKDIAAIIVEPIAGNMNLIPAAPDFLTGLRELCNQYGSLLIFDEVITGFRVAKGGAQSLYNIRPDLTALGKIIGGGMPVGAYGGRREIMNQLSPEGPVYQAGTLSGNPVAMAAGLATLKELTAENFYSNLKEKTERLVMGILSRAKAAKIPLTANFSCGIFGLIFTSEERVTRYAQAVNGNVEHFRSFFHKMLDNGVYLAPSAFESGFISAAHTNKEVDKTLDIIENIFSVSETYLRISV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANR29_DANRE
Sequence: MSFKKETPLANAVFWAARKGNLALLQLLLNSGRVDVDCKDAYGTTALMVASYSGHYECVRELIMQGADINLQRETGSTALFFASQQGHNEIVKLLFEFGASTEFQTKDGGTALCAACQFGHSRVVDTLLKNGANVHDQLNDGATALFLASQEGHVNLIRQLLSSGAKVNQPREDGTAPLWMAAQMGHSEVVKVLLLRGADRDADRKDGSTALFKAAHKGHCSVMEELLKFSPSLGILKNGSTALHAAVMGGSLKAVDLLLKANADPALPNTNNELPRDLTKSERILRVLRLPLMNGES
What are the official names of this protein?
Ankyrin repeat domain-containing protein 29.
Protein: WHIA_STRPZ
Sequence: MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSITTENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADSFFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQLMQKFMLDAKTIEHKSGAVTYVQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDINRANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQVADALEFPITKSGVNHRLRKINKIADDL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RL4_PSYIN
Sequence: MELVLKDAQSALEVSETTFGREFNEALVHQVVVAYAAGARQGTRAQKTRSDVSGGGKKPWRQKGTGRARSGTIRSPIWVGGGVTFAARPQDHSQKVNKKMYRGAVKSILSELVRQDRLIVVEKFSVEAPKTQELKAKLKELDLKDVLIITEELDENLFLAARNLYKVDVRDVQGIDPVSLIAFDKVLVTAAAVKKIEESLT
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SYA_DESAP
Sequence: MNSSEIRKRYLEFFAARGHRVIPSASLIPGNDPTLLWTSAGMVPFKPYFTGVATPEFRRVVTCQKCLRTPDIEMVGRTARHHTFFEMLGNFSFGDYFKERAIPWAWEFVTRDLGLAPEHLWISVYLDDNEAFDHWRGLGVPAERIVRLGRDTNFWEIGVGPCGPCSEVYYDRGPAYGCESASCGPGCDCDRWLEIWNLVFIQYFRNEAGDYSPLESPGIDTGMGLERVASVLQGVNTNFDTDLFRGLIDYTAGVLGVRYGDDPAGDAALKVIADHGRAITFAIADGVLPSNEGRGYVIRRLLRRAVRKALLLGREKPFLEGVALAVIEQMAGAYPELETARDSVRKVVRFEEERFRQTLTQGNEIIGRLIAEARAEKRSTLEGAAAFQLYDTYGFPLELTREICAEQGLAVDEAGFEAALKAQQQKARSSRRETRYVEERETFFRNLRDEIGLTRFVGYEQLEADAGVRALIRDGQRVPAAGSGEQVSLVVDTTPCYAESGGQVGDHGLIEGENVRGRITDTFAPVEGLHVHEVVVEAGVLEEGARIRILVDGSRRRKICRNHTATHLLHRTLKAVLGTHVNQAGSLVAPERLRFDFTHIQPLSEAELAEVESRINEIVLSNLRVESFQTSFDRARELGAVALFGEKYGDLVRVVQIDGVSMELCGGTHVLSTAEIGPVKITAESSVGAGLRRLEAVTGMEALAFLNSRNEQLHRIAQAVRVPVSELVVHVERLLDHQKKLQRENEQLQDRLQVYEVKELLDRASTHEGVRILATSVRARDMAELRSMLDLLRERLGSAVIVLGSAVNGKVSLVASVSRDLVARGLHAGAIIKEAAAVAGGGGGGRPEMAQAGGKNPEKLTEALEKARQVVLRRVDGGSA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYAL1_HUMAN
Sequence: MAAHLLPICALFLTLLDMAQGFRGPLLPNRPFTTVWNANTQWCLERHGVDVDVSVFDVVANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFGGLPQNASLIAHLARTFQDILAAIPAPDFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQHPDWPAPQVEAVAQDQFQGAARAWMAGTLQLGRALRPRGLWGFYGFPDCYNYDFLSPNYTGQCPSGIRAQNDQLGWLWGQSRALYPSIYMPAVLEGTGKSQMYVQHRVAEAFRVAVAAGDPNLPVLPYVQIFYDTTNHFLPLDELEHSLGESAAQGAAGVVLWVSWENTRTKESCQAIKEYMDTTLGPFILNVTSGALLCSQALCSGHGRCVRRTSHPKALLLLNPASFSIQLTPGGGPLSLRGALSLEDQAQMAVEFKCRCYPGWQAPWCERKSMW
What is the function of this protein?
May have a role in promoting tumor progression.  May block the TGFB1-enhanced cell growth.
What are the official names of this protein?
Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted. Lysosome.
Protein: PSUG_METNO
Sequence: MPHPLLDFAPEVRSALDAGAPVVALESTIVTHGMPHPQNVETARAVAAVVRANGAVPAIVAVVAGRIRIGLPEEILDWLGTAKEVLKLSRADLPHAVAAGLHGSTTVAATMICAHRAGIRVFATGGIGGVHRGVEETLDISADLDELARTPVAVVCAGAKAILDLPRTLEYLETRGVPVVGYRTDRFPAFWSRDSGLPAPLRLDTPEAIAALMRTKEALDLGGGILVANPVPEADEIPAREIAALIATAVAQARAAGIAGKAVTPFLLSRLLDLTGGRSLSTNIALVKNNAALAAQLAVALRGARSSGPQAGAGAPGAEPGPARRTSPARAPSGEGW
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: ARH_MOUSE
Sequence: MDALKSAGRALIRSPSLAKQSWAGGRHRKLPENWTDTRETLLEGMVFSLKYLGMTLVERPKGEELSAAAVKRIVATAKASGKKLQKVTLKVSPRGIILTDSLTSQLIENVSIYRISYCTADKMHDKVFAYIAQSQQNESLECHAFLCTKRKVAQAVTLTVAQAFKVAFEFWQVSKEEKEKREKANQEGGDVPGTRRDSTPSLKTLVATGNLLDLEEVAKAPLSTVSANTNNVDETPRPQVLGNNSVVWELDDGLDEAFSRLAQSRTNPQVLDTGLSAQDIHYAQCLSPTDWDKPDSSGIDQDDDVFTF
What is the function of this protein?
Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts).  May be required for LDL binding and internalization but not for receptor clustering in coated pits.  May facilitate the endocytosis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits.  May also be involved in the internalization of other LDLR family members.  Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface.  Required for trafficking of LRP2 to the endocytic recycling compartment which is necessary for LRP2 proteolysis, releasing a tail fragment which translocates to the nucleus and mediates transcriptional repression (By similarity).
What are the official names of this protein?
Low density lipoprotein receptor adapter protein 1, Autosomal recessive hypercholesterolemia protein homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM115_BOVIN
Sequence: MQRALPGARQHLGAILSSASVVVKALCAAVLFLYLLSFAVDTGCLAVTPGYLFPPNFWIWTLATHGLMEQHVWDVAISLATVVVAGRLLEPLWGALELLIFFSVVNVSVGLLGAFAYLLTYMASFNLVYLFTVRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVSVVPMLLLGLLLLLRLATLLQSPALASYGFGLISSWVYLRFYQRHSRGRGDMADHFAFATFFPEILQPVVGLLANLVHGLLVKVKICQKTVKRYDVGAPSSITISLPGTDPQDAERRRQLALKALNERLKRVEDQSVWPSMDDDEEEAGAKVDSPMPSDKAPTLPGKGAVPESSLITFEAAPPTL
What is the function of this protein?
May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum.  May indirectly play a role in protein glycosylation in the Golgi.
What are the official names of this protein?
Transmembrane protein 115.
What is the protein family that this protein belongs to?
Belongs to the TMEM115 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein.
Protein: Y3154_BACHK
Sequence: MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAAVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDHHVS
What are the official names of this protein?
UPF0316 protein BT9727_3154.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PETN_JASNU
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: GATB_METEP
Sequence: MTERVDPKKLIKGGLHDWEVVIGMEIHAQVTSRSKLFSGASTEFGGEPNDHVSLVDAAMPGMLPVINEECVAQAVRTGLGLKAQINLRSVFDRKNYFYPDLPQGYQISQYKDPIVGEGEVLVDLPEGESMTVGIERLHLEQDAGKSLHDQDPTKSFVDLNRSGVALMEIVSRPDLRSSEEARAYVTKLRTILRYLGTCDGDMEKGSLRADVNVSVRRPGEPLGTRCEIKNVNSIRFIGQAIETEARRQIAILEDGGKIDQETRLYDPGKGETRSMRSKEEAHDYRYFPDPDLLPLEFDQAYVDALASGLPELPDAKKARFIKDFGLSAYDAGVLVAERASADYFEAVARGRDGKAAANWVINELFGRLNKEGRSIEDTPVSAEQLGTIVDLIGDGVISGKIAKDLFEIVWSEGGDPRAIVEARGMKQVTDTGAIEAAVDAIIAANPDKVEQAKAKPTLLGWFVGQTMKATGGKANPAAVNALLKDKLGIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: MYCBP_BOVIN
Sequence: MAHYKAADSKREQFRRYLEKSGVLDTLTKVLVALYEEPEKPNSALDFLKHHLGAATPENPEIELLRLELAEMKEKYEAIVEENKKLKTKLAQYEPPQEEKRAE
What is the function of this protein?
May control the transcriptional activity of MYC.  Stimulates the activation of E box-dependent transcription by MYC (By similarity).
What are the official names of this protein?
c-Myc-binding protein, Associate of Myc 1, AMY-1.
What is the protein family that this protein belongs to?
Belongs to the AMY1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates into the nucleus in the S phase of the cell cycle.
Protein: EXC6B_MOUSE
Sequence: MERAKMAEESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDVYTIFDAEVESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLHIYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHTTQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVNQLFDMLLEIRDQYSETLLKKWAGVFRNILDSDNYSPIPVTSEETYKKVVGQFPFQDIELEKQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLDNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFAQFRKNERDKQKLIDTVAKQLRGLISSHHS
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 6B, Exocyst complex component Sec15B, SEC15-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the SEC15 family.
Protein: CHLN_CHAGL
Sequence: MNSAISDTLTFECETGNYHTFCPISCVAWLYQKIEDSFFLVVGTKTCGYFLQNALGVMIFAEPRYAMAELEEGDISAQLNDYQELKNICLQIKKDRNPSVIVWIGTCTTEIIKMDLEGMAPRLEAEIGIPIVVARANGLDYAFTQGEDTVLAAMAQRCPEISVASKQNQPMGSAFSQTLKVSNQQDHPPLVLFGSLPSTVASQLDLELKRQSIEVSGWLPSQRYTDLPLLGEGVHVCGVNPFLSRTATTLMRRRKCKLISAPFPIGPDGTRAWIEKICSVFGIQPQGLEERENQIWDGLKDYIDLVRGKSVFFMGDNLLEVSLARFLIRCGMVVYEIGIPYMDKRYQAAELALLQKTCQDMNVPMPRIVEKPDNYNQVQRMRELQPDLAITGMAHANPLEARGISTKWSVEFTFAQIHGFTNARDILELVTRPLRRNHSLQGLGWSSLVKEQNQLIPS
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPG_THEMA
Sequence: MRKSVKVGKVVIGGEAPVSVQSMTTTKTADVEKTVSQIKSLERAGCEIVRVAVQDEEDAKAIRRIKEQIEIPLVADIQFDYRLAILSIENGADKIRINPGNMSRDRLKDVVAAAKGKGIPIRVGANVGSIKRRTSERWKDLAESALEEVRLLEKEGFYDIIVSVKSSDVLETIKANEYIAEKVEYPIHLGVTEAGVSETAIVKSSIAIGHLLLKNIGDTIRVSISGDPVREVIVGKKILIALGLREGVEVIACPTCGRAEIDVENMAKMIEENFFHVQKRLKIAVMGCVVNGIGEGKDADLGVAGLRDGAVIFVKGEIKERVSKEFVLERLKYYLNELLEEVER
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PYRB_SHIDS
Sequence: MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RHG42_HUMAN
Sequence: MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILEKHLNLSAKKKESHLQEADTQIDREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDIDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKSGGIPWIATPSSSNGQKSLGLWTTSPESSSREDATKTDAESDCQSVASVTSPGDVSPPIDLVKKEPYGLSGLKRASASSLRSISAAEGNKSYSGSIQSLTSVGSKETPKASPNPDLPPKMCRRLRLDTASSNGYQRPGSVVAAKAQLFENVGSPKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL
What is the function of this protein?
May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle.
What are the official names of this protein?
Rho GTPase-activating protein 42, Rho GTPase-activating protein 10-like, Rho-type GTPase-activating protein 42.
Protein: SYE_LYSSC
Sequence: MTKEVRVRYAPSPTGFLHIGGARTALFNYLYAKHHNGKFIVRIEDTDIERNVEGGEASQLDNLKWLGIEYDESIDIGGPYAPYRQMERLDIYKEHAEKLLAQGAAYKCFCSSEKLEASREEQKARGVAAPTYDGTCRHLSAEEVAAKEAAGEPYTIRMRVPENVTYDFEDLVRGQVTFESKDIGDWVIVKANGIPTYNYAVVLDDHFMEISHVFRGEEHLSNTPKQMMIFDAFGWEYPRFGHMTLIINENRKKLSKRDESIIQFVTQYKDLGYLPEAMFNFFALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPSMFDKQKLTWMNNQYIKKLSLEEVVALSLPHLQKAGLLPDELSAVQHAWATDLIGLYHDQMSFGAEIVELSSLFFKDHIEYDEEAKAVLAGEQVPEVMAAFKAQLEELEEFTPDAVKAAIKAVQKATGHKGKNLFMPIRVVTTGETHGPELPNAICLIGKEKAIDRVEKFAQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDJI_BACSU
Sequence: MSFFRNQLANVVEWEEFRDDMIFYKWNNREIKKGSRLIIRPGQDAVFLNNGRVEGVFQDDGDYDIESEIIPFLSTLKGFKFGFNSGMRAEVLFVNTKEFTVRWGTKQAINIPAAGMPGGMPIRANGTFNFKVQDYISLIDKIAGVKDQYFVEDIKTRIISILDQLLMKWITREGKDMFNLQANAFDIAKGIQEDLDMQLISDGMTVTGFQIMSFNYPQEVQDMITKNASYGMVGDVNRYQQISMTDGMASGKMSGSGAASDMAGMMMGMNMANQMMNQMNQNQQAQSSGPQSTGSGSKPNFCPNCGTKTGEANFCPNCGQKLV
What are the official names of this protein?
Uncharacterized protein YdjI.
Protein: HDT2_ARATH
Sequence: MEFWGVAVTPKNATKVTPEEDSLVHISQASLDCTVKSGESVVLSVTVGGAKLVIGTLSQDKFPQISFDLVFDKEFELSHSGTKANVHFIGYKSPNIEQDDFTSSDDEDVPEAVPAPAPTAVTANGNAGAAVVKADTKPKAKPAEVKPAEEKPESDEEDESDDEDESEEDDDSEKGMDVDEDDSDDDEEEDSEDEEEEETPKKPEPINKKRPNESVSKTPVSGKKAKPAAAPASTPQKTEEKKKGGHTATPHPAKKGGKSPVNANQSPKSGGQSSGGNNNKKPFNSGKQFGGSNNKGSNKGKGKGRA
What is the function of this protein?
Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
What are the official names of this protein?
Histone deacetylase HDT2, HD-tuins protein 2, Histone deacetylase 2b.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase HD2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus.
Protein: E4PD_SALPC
Sequence: MTVRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRHEREQLFVGDDVIRILHERTLADLPWRELGVDVVLDCTGVYGNREHGEAHIAAGAKKVLFSHPGSNDLDATVVFGVNQNQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKASEVNQLLQKAAQGAFHGIVDYTESPLVSIDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAVGFRLDASASTKL
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1195_STRP3
Sequence: MADKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIVTLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQTYGPKCLEDGEYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN
What are the official names of this protein?
Uncharacterized acetyltransferase SpyM3_1195.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: PPE49_MYCTO
Sequence: MVLGFSWLPPEINSARMFAGAGSGPLFAAASAWEGLAADLWASASSFESVLAALTTGPWTGPASMSMAAAASPYVGWLSTVASQAQLAAIQARAAATAFEAALAATVHPTAVTANRVSLASLIAANVLGQNTPAIAATEFDYLEMWAQDVAAMVGYHAGAKSVAATLAPFSLPPVSLAGLAAQVGTQVAGMATTASAAVTPVVEGAMASVPTVMSGMQSLVSQLPLQHASMLFLPVRILTSPITTLASMARESATRLGPPAGGLAAANTPNPSGAAIPAFKPLGGRELGAGMSAGLGQAQLVGSMSVPPTWQGSIPISMASSAMSGLGVPPNPVALTQAAGAAGGGMPMMLMPMSISGAGAGMPGGLMDRDGAGWHVTQARLTVIPRTGVG
What are the official names of this protein?
Uncharacterized PPE family protein PPE49.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: EPI1_PHYIN
Sequence: MKSALLFTLVVAAVHAQSPQVISPAPRRESNEIDCPEYCLDVYDPVGDGEGNTYSNECYMKRAKCHNETTPPAWKDLVLITGSSTGEQPPSKKCSTVCPDVELPVCGSNRVRYGNPCELRIAACEHPELNIVEDSGKACVGSKVTPQEG
What is the function of this protein?
Secreted effector that interacts with and inhibits the pathogenesis-related P69B subtilisin-like serine protease of host tomato (PubMed:15096512).  Inhibition of host proteases by a pathogen extracellular protease inhibitor forms a specific type of defense-counterdefense mechanism between plants and microbial pathogens (PubMed:15096512).
What are the official names of this protein?
Extracellular protease inhibitor 1, Secreted effector EPI1.
What are the subcellular locations of this protein?
Secreted. Note=Localizes to host apoplast where it targets defense proteases for inhibition.
Protein: NRDR_METSB
Sequence: MRCPYCGSLETQVKDSRPTDDASAIRRRRVCPDCGGRFTTFERVQLRELTVLKKSGRRAPFEREKLMRSLEIALRKRPVEPERVERMVNGIVRQLESQGESEIASDRIGELVMEGLRALDSVAYVRFASVYRNFREARDFNALIDELDGAAQPEAPSKDDGGTDEPPAKTRAPTRA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.