PharMolix/UniProtQA huggingface dataset:
Protein: ASTD_VIBA3
Sequence: MTQWIAGQWVAGQGDAMTSVSPYNNEVVWQGDSATPAQVESAVAAARDAFLVWKKLSFAEREAIVLNFAEKVKENSEEIAQIIAKETGKPIWETRTEAGAMAGKIAISIRAYHERTGEASREAAGNQIVLRHRPLGVMAVFGPYNFPGHLPNGHIVPALLSGNTVVFKPSEQTPWTGEFAMKLWQEAGLPAGVINLVQGAKETGIALADAKGLDGVLFTGSANTGHILHRQFAGQPGKMLALEMGGNNPMVISDQFGDADATVYTIIQSAFISAGQRCTCARRLYVPVGEKGDQLLDKLVAATLKIRVDQPFAEPAPFMGPQISEAAAKFILDAQANLQSLGGVSLVEAKAGEAAFVSPGIIDATNIAELPDEEYFGPLLQVVRYQSLEQAVELANDTRFGLSAGLVSTDDSEWEYFVDHIRAGIVNRNRQLTGASGDAPFGGPGASGNLRPSAYYAADYCAYPMASMEGGETQLPATFSPGIEL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: NDK_STAAM
Sequence: MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIRGDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2298_MYCSK
Sequence: MSGHSKWATTKHKKAIIDARRGKNFAKLIKNIEVAARTGGGDPGGNPTLYDAIQKAKKSSVPNDNIERARKRGAGEEAGGADWQTITYEGYGPNGVAVLIECLTDNRNRAAGEVRVAMTRNGGNMADPGSVSYLFSRKGVITLEKNGLSEDDVLMAVLEAGAEEVTDLGDSFEIISEPTDLVAVRTALQDAGIDYDSADASFQPSVTVPLDAEGARKVMKLVDALEDSDDVQDVYTNADIPDEILAQLEE
What are the official names of this protein?
Probable transcriptional regulatory protein Mkms_2298.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENLYS_BPT1
Sequence: MSLKNNVIGASIGAALTLTPTLLERIEGIEYEVYYDIAGVPTVCSGITGPDVIPGKKYTKRECDALLIKHIGVAQRYVDKKVKVDIPVTMRASLYSFTFNVGTGAFGSSTMLKLINQRKHKEACNQLWRWVYYYNPKTKKREVSRGIKNRRAEEYAYCVKEL
What is the function of this protein?
Signal-arrest-release (SAR) endolysin with lysozyme activity that degrades host peptidoglycans and participates with the pinholin and spanin proteins in the sequential events which lead to programmed host cell lysis releasing the mature viral particles.  Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm where it breaks down the peptidoglycan layer.
What are the official names of this protein?
SAR-endolysin, Endolysin, Lysis protein, Lysozyme, Muramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side. Note=Secreted as a signal-anchored, membrane-tethered, inactive endolysin which is subsequently refolded, activated and released by membrane depolarization driven by the pinholin.
Protein: PNP_XYLFA
Sequence: MAKITKTFQYGKHTVTLETGEVARQANGAVIVKMDDTVLLVTVVAAKTAREGQDFFPLTVDYQEKFYAGGRIPGSFFKREGRATEKETLISRLIDRPIRPLFPEDYKNEVQIIAMVMSLDPEIDGDIPAMIGASAALSLAGIPFKGPIGAAKIGYNDGQYILNPTVSELKKSQLELVVAGTANAVLMVESEAALLSEEVMLGAVIFGHREMQKVIQVIDSLTAEAGTQPSDWVPPAKNDALVIALKEVIGGRLSDAFHIRDKLQRRDAIAAVKDDVIQQLAGRLEVEGWNLAELLKEFGELEYRTMRDALLDTKVRIDGRSLEAVRPITVKVGVLPRVHGSGLFTRGETQAIVVTTLGTARDGQVIDAVTGEYKENFLFHYNFPPYSVGECGRFGVPKRREIGHGRLARRGVLAVMPSLDEFPYTIRVVSEITESNGSSSMASVCGSSLALMDAGVPVKAPVAGIAMGLVKEGERFVVLSDILGDEDHLGDMDFKVAGTSEGVSALQMDIKIEGITEEIMRQALQQAKVGRLHILGEMDKALAAPRAELSDYAPRLLTIKIHPDKIRDVIGKGGSTIQAITKDTGTQIDIQDDGTIIIASVNNAAAREAKCRIEQITSDVEPGRIYEGKVAKIMDFGAFVTILPGKDGLVHVSQISSERVERVGDKLKEGDVVRVKVLEVDKQGRIRLSIKAVEEEVASI
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3F_PANTR
Sequence: MATPAVPVSAPPATPAPVPAAAPVSAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAATTAAPGQTPASAQAPAQTPAPALPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPNPIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL
What is the function of this protein?
Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f, Deubiquitinating enzyme eIF3f, Eukaryotic translation initiation factor 3 subunit 5, eIF-3-epsilon, eIF3 p47.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y110_PASMU
Sequence: MLSAILHGKKTGSGLAGRQFKIGETQGAEDLLTATIFERISYLPNNTFQEVIKKLFDDKEDIGNLQNIEYWPKWMNKNRFIEPDVVLTGTNGKNIIIEAKRYDNTQQQYAIQLANEIMSYYDSTGLSNPILLAIGGMDSYDKKRVEKIKKEIKNILIQNSFNREFTLYCISWKKLYQILESSIHQSEIFLQRILSDIREAYIWHGVRYKSIQWLKSLKRNDIIHISIPIKIRIEKKWIELKKMNISKTHFPSFLGE
What are the official names of this protein?
Uncharacterized protein PM0110.
Protein: PSB_METST
Sequence: MNQTENMEGTTTVGFVCTDGVVLATETRATMGSLVANKNADKLFQIDDKIGATIAGTVSHAQSLMDILKAEISLYKLRNEKDMSIDALAVLTSNILKSRPYYVQTILAGVDKDGAKLYTLDPSGSYIPDTFTSTGSGSPYAFGVLEDRYNEDITTEEGKKIAIKAITSAMERDVYSGNNYRLGVITKDGMKIYTKEEIAQIKKQL
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REP_MSVK
Sequence: MASSSSNRQFSHRNANTFLTYPKCPENPEIACQMIWELVVRWIPKYILCAREAHKDGSLHLHALLQTEKPVRISDSRFFDINGFHPNIQSAKSVNRVRDYILKEPLAVFERGTFIPRKSPFLGKSDSEVKEKKPSKDEIMRDIISHSTSKEEYLSMIQKELPFDWSTKLQYFEYSANKLFPEIQEEFTNPHPPSSPDLLCNESINDWLQPNIFQSSDERSRKQSLYIVGPTRTGKSTWARSLGVHNYWQNNVDWSSYNEDAIYNIVDDIPFKFCPCWKQLVGCQRDFIVNPKYGKKKKVQKKSKPTIILANSDEDWMKEMTPGQLEYFEANCIIYIMSPGEKWYSPPELPPTEAVHSDRS
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities.  Acts as an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: SYH_CHLCV
Sequence: MKVALPKGVFDIFPYITDAKHMWRHTSLWHRVEDVIHEVCDLYGFSEIRTPVFEKSEVFLHVGEQSDIVKKEMYTFLDKKGRSLTLRPEGTAPIVRSFIDNPMSQREDNKFYYILPMFRYERQQSGRYRQHHQFGVEAIGVRHPLRDAEVLSLLWNFYSAIGLQYMQIQLNFLGGSATRKRYDQVLRGYFLQHLDSLSSLSKERFNTNLLRILDSKEPEDQEIIKSAPPILEYVSDEDRKYFDEILSALSALNIPYSINSRLVRGLDYYTDVVFEAITTFGGHSYALGGGGRYDGLIAASGGVATPACGFGVGLERVIQTLLAQGNLTLPSSHKLRLIPVEPEADSFCFVWAQHLRSLGIPTEVDWTHKKLKAALKTADTEKVTFVCPIGERELLSEQLTIKNMSLRQEFSGSKQEVEQRLLYEIQNTSL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXC5_HUMAN
Sequence: MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C5, Homeobox protein CP11, Homeobox protein Hox-3D.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAD20_CHICK
Sequence: MWTSGRMSNAKNLFGLGVSLYFWGLMDLTTTVLSGSARPLTEGPEDNLSDKLHQRMKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERSQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVASVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSRTGLIRTALMNMDREAKEYYEVIVQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPVSSTVGRVVAKDLDEGINAEMKYSLVDGDGLDVFDINTDPNYQVGIITVRKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFRDTTTVHISVEDVDEPPVFEPSFYFVEVPEDVEIGATIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITSGALMTARPLDREDVSWHNITVLAMELNNPSQVGSVSVTVKVLDVNDNAPEFARFYEAFVCENAKAGQLIQTVSAIDRDDPQEGQHFYYSLAPEAANNPNFTLRDNQDNTAWILTRRSGFRQHEQNIFYLPILISDNGRPVLSSTGTLTVHVCSCDEGGMVMSCNAEAYVLPVSLSRGALIAILACIFVLLVLVLLILSMRRQRKQPYIIDEEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQLVVKNRQDMLPEIESLSRYVPQACIMDNNVHNYVLAKLYEADMDLWAPPFDSLQTYMFEGNGSVAESLSSLQSVTTDSDQSYDYLTDWGPRFKKLAEMYGATDSSGALW
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
What are the official names of this protein?
Cadherin-20, F-cadherin, MN-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PSTB_PHOLL
Sequence: MNIVNDIASSKIQVHNLNFYYGKFHALKNITLNIAKNKVTAFIGPSGCGKSTLLRTFNKMYELYGEQRAEGKILLDGKNILTDKQDVALLRANVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRAEMDERVQWALTKAALWSETRDKLYQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELISELKSEYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSDTDTLFTTPKMKQTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COG8_CAEEL
Sequence: MDSDYIFHNGDDIRNMGLEEMRRQKVLLASELKAIDAQISDLAFNNYGTYADAGRATHDCSKTFGEMRDKTVNLSDQAEELTSAFVEFRAKAKQLSEEQDLVRKALDKSNPIWELLTLPSRMDICIRAGYYDLAYTLTNYGLQLQQQTQLYRNPLIKKVADHLVEARAYLLEELFNKFAGPLDLAESIKVVNNVRKMPSLTANQLRIAVLQHRDIYLEKQILDISGNVDMIVQAIEIYRTSMYDTLVLYLAVFPENEVVRKNPNADPRWESWPVLPPNSILSQWVISNVKKMLDLITKADVKSAVDLSAVWTKLMAMASSFGRMGIDFRPLIAGKLTKLIEQRFRQNVQEATSRLTGSSRDIVMIGIDPASLPQFETAPDSPPVAAAELSLWDDMTIYTNSVVDALNGLRFILTPVVLSTVVVSLRDSIRSILTWLASSHSNSANFSRAVRIVCTSVAPFFEKCVAFFFPPATVSKIFGSSISKRQYLQFIELDMKQLAASCDGAEKIEEIVKPLLQKRTLEEIGLENVLKPTKPEEEKTKFFLEETVEDGPGLAEPQEEASESVKEQETTSELEKKHGTDFETAETQEMVSEPVKEHETTSELTKEQEPAFEPEKLHETPPEPMEPQNFGESEAKAAHNPEAHLELGETSENQEIREQEHKEVVITSTEPEFHEIDLNSAVLIPKIAVEPQLDPISEYLTELTQDDPIEEEEGWGWGDDDGEEQEISSKEVESPKEKCKKDD
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 8, COG complex subunit 8, Component of oligomeric Golgi complex 8.
What is the protein family that this protein belongs to?
Belongs to the COG8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: GATY_SHIFL
Sequence: MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEVDALYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPVLDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFLQSLKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: RRF_BURA4
Sequence: MSVADVKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVEKAIREADLGLNPATAGDLIRVPMPALTEERRRELTKVVKSEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDDVQKLTDKHVAEVDKLVQSKEAEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DML1_YEAST
Sequence: MHEVVTISVSQRANHLTTQFFNIQEGYLQLSKEQQVNDSKIFLNSVVDKVSKTISYAPRALLWDARTGNGSLGTYQYSESQDYHFGNEDKFKEQTVIKTHPRIPKSEYQSSLDAGAPLPCLNRENTMYWSDYSKLIYGPSSFNILRNWYHDTENPNQPDFQNLGERKFDRYSIGYDEFTENYLQEFFDGNLHRELEKCDTLQGFNLVSDMESGWGGFSSALLVELRNELPKKAVFSWGHNEDDPFTDDFPMKRLSKKWLPIISNKLRSTINMMQESDLYFPLYAAPGLTNWETAGKSCRIFDSINATISQSNLEQRKTMDYLTTAITLGYSSRNMVTGMVIGDTDYSFCSRVLPFKNSHKPNSTHIFSKSFIDRGNQTHKHHSEPDSRSKMIEMYTHRYFPSDTIPTEFSNDREFVLELESSEKNRDIFKHWNEFVVRYFKNDSDREELKNELSDYASAYESGWYEDEDSGDDDM
What is the function of this protein?
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
What are the official names of this protein?
Protein DML1, Drosophila melanogaster misato-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
Protein: HGD_PSEA7
Sequence: MNLDSTALAYQSGFGNEFSSEALPGALPVGQNSPQKAPYGLYAELLSGTAFTMARSEARRTWLYRITPSAKHPPFRRLERQIAGAELDAPTPNRLRWDPLALPEQPTDFLDGLLRMAANAPGDKPAGVSIYQYLANRSMERCFYDADGELLLVPQLGRLRLCTELGALQVEPLEIAVIPRGMKFRVELLDGEARGYIAENHGAPLRLPDLGPIGSNGLANPRDFLAPVARYEDSRQPLQLVQKYLGELWACELDHSPLDVVAWHGNNVPYKYDLRRFNTIGTVSFDHPDPSIFTVLTSPTSVHGLANIDFVIFPPRWMVAENTFRPPWFHRNLMNEFMGLIQGAYDAKAGGFVPGGASLHSCMSAHGPDAESCDKAIAADLRPHRIDQTMAFMFETSQVLRPSRAALETPALQNDYDACWASLVSTFNPQRR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: GMEB1_MOUSE
Sequence: MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENSAAVVAVETHSIHKIEEGIDASSIEGNEDMEIAYPITCGESKAVLLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKESEEISEDTLMFWKGIADVGLMEEVVCNIQKEMEELLRGVQQRLIQAPFQVTDAAVLNNVANTFGLMDAVKRVLDNRRKQVEQGEEQFLYTLADLERQLEEQKKQAQDPRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSNSPDTVTIHPSSSLALLSSTSMQDGSSLGNMATMVSPMELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDSEADDTEGKAVILETGLRTEEKVVAEMEEHQHQVHNVEIVVLED
What is the function of this protein?
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids.  Binds also to the transferrin receptor promoter (By similarity).
What are the official names of this protein?
Glucocorticoid modulatory element-binding protein 1, GMEB-1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=May be also cytoplasmic.
Protein: NUOB2_BURMA
Sequence: MANHPLTLEKDGFIVTTLDAAMAAAQKNSLWYMTFGLACCAVEMMHAAGARYDMDRFGMIPRASPRQCDLMIVAGTLTNKMAPAMRRVYDQMAEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGLMQLQRKVAERSTHSRPKLFARP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LGT_MYCPA
Sequence: MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAGIVAALLIGDRRWEARGGERGVIYDIALWTVPFGLVGGRLYHLATDWRTYWGPGGAGFGAAVRIWDGGLGIWGAVALGAVGAWIGCRRHGIPLPAFADALAPGIILAQAIGRLGNYFNQELYGRETTLPWGLEIFYRRDPSGYIDPHSLDGVSTGQVALVVQPTFLYELLWNLLIFVALLYADRRLTLGHGRLFALYVAGYCVGRFCVELLRDDTATHIAGIRINSFTSTFVFIGAVVYLMAAPKGREDPESLRGNQYVEEEPAEPEPATVAATTEAATEGVAAPADGAEAAGADATAQRPEESAEPDVEKPESEETEAAEEASEPEAEEPEAPEAEEPEEPETEEPEADSGEEPEEESGEAPEQLVAEEPEPAPQQPETKRRWGARLRERLSGR
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GREA_ANASK
Sequence: MQRVPMTKGGLVRLKDELRRLKSVERPKIVKEIAEARAHGDLSENAEYHAAKEKQSHIEGRIAQVEHWIASAEVIDVTKHAGDRVVFGATVSLEDAESGDQVTYRIVGELEADLKQGKISVTSPIARALIGRSEGDTVVVRSPGGEKEYEIQSVAFVEEELPTESE
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ADDA_STRR6
Sequence: MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSAQNILVSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQETDDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLILENEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWLSESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQFAKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGRLIILKENFRSSSEVLSATNDVFERLMDQEVGEINYDNKHQLVFANTKLTPNPDNKAAFLLYDKDDTGEEEESQTETKLTGEMRLVIKEILKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMASSQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIHKSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQDSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLILLGKDEVQVVKV
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: ENOB_SALSA
Sequence: MSITKIHAREILDSRGNPTVEVDLYTAKGRFRAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIEKKFSVVDQEKIDHFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHKDVILPCPAFNVINGGSHAGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIEKAGYPDKIIIGMDVAASEFYKAGKYDLDFKSPDDPARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWTKFTAAVDIQVVGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGAKAKFAGKDYRHPKIN
What is the function of this protein?
Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate.
What are the official names of this protein?
Beta-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 3, Muscle-specific enolase, MSE, Skeletal muscle enolase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI17B_BOVIN
Sequence: MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGMRHRLRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSVPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPGQLPSKEGTPGPGYPSYQQYH
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim17-B.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.