PharMolix/UniProtQA huggingface dataset:
Protein: ZAPB_HAES1
Sequence: MSLEILDQLEEKIKQAVETIQLLQLEIEELKEKNELSRQTNEQLRSENEHLKTEHHNWQERLRSLLGRIDNI
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: EIF3A_ASPFC
Sequence: MPPPPHIKPENVLKRAQELIAVGQAPAALNVLHEHVTSKRTRSSPIASLEPVMLLFVELCVDLRKGKAAKDGLYQYKNIAQNTNVGTIEVVLKKFIELAEKKVTEAQAKADEIQSSLESAAPSSNVEDLEAIETPETILLATVSGEQSRDRTDRAVVTPWLKFLWETYRTVLEILKNNARLEVMYQTTALQAFQFCLKYTRKTEFRRLCELLRNHVQNAAKYSAQMHAINLSDPDTLQRHLDTRFQQLNVAVELELWQEAFRSIEDIHTLLSLSKRPAKNVMMANYYEKLARIFLVSENYLFHAAAWNRYYNLLRQSAAALAAGQGTKKENPSVTEADMTKAASFVLLSALSIPVISTSRSRGALVDVDEARKNKNARLTNLLGMAQPPSRAVLFRDALNKGLLKRARPEIRDLYNILEVDFHPLSICKKITPILKQIGADPEMEKYVLPLQQVILTRLFQQLSQVYESVELKFVYELAQFPDPFQITPAMIEKFIMNGCKKGDLAIRVDHTAGVLTFDTDIFSSAKALHSGSAAGSAESEVGSVQRLQNTPAEIARLQLTRLAKTLHVTCMYVDPSYNEARIQAKKAAQARAEAGAAKEHEETLARRVLIEKKKEAATDALQRKQREEETRKRIRNQQLQEAEKQRLLDEQREREKKRLRDEQERIRQQELKKQLEELKSGVKGIDISEIDLEDLDANRLRAIKLAQLEKEKNELNERIRTTAKRIDHLERAFRREELKHIPEDYEAQKKRDMELYEAIKAETLKEAEEKHKEAVALKHRLSRLVPVFSSFRKEVSEKRHEEFEKRRKAAEREFEAKKKQRIKEVQERRRRERAEREAEERRRKEEEERAKREEEERIAKEEERRRILAEEKAKREEERKRLDEIAQRQKQREEEAEARRAARKSGLAEPPTRAAELERPVERTAPRLNLVSRTGSGPSWRERQAAKEAAGAAPAPAAAEAPKEEVQLPRRTGGYVPPHLRSGANASPATPPSNGPAPEKYVPRHMRESSSSQPPSRTQTPPAAAPASSDKPEASPAPQKWVPRWKQQQQ
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_CLAMS
Sequence: MTDIVYDKDADLSLIQGRKVAVIGYGSQGHAHALNLRDSGVEVVIGLKEGSTSRAKAEEQGFTVKTPSDASAWADVIVILAPDQHQRGLYADSVRDNLTEGKTLVFAHGFNIRFGYIEAPEGVDVVLVAPKGPGHTVRREFEAGRGVPVIVAVEVDASGKAWDLAWSYAKGIGGLRAGGIRTTFTEETETDLFGEQAVLCGGTSQLVQYGFETLIEAGYQPQIAYFEVLHELKLIVDLMWEGGIAKQRWSISDTAEYGDYVSGPRVISPDVKENMKAVLADIQSGAFADRFIKDQDAGAPEFLELRKKGEEHPIESTGRELRKLFAWNKADDDYTDGSVAR
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: GST5_CHICK
Sequence: PNYKLTYFNLRGRAEISRYLFAYAGIKY
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase 5, GST class-sigma, GST-CL5.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Sigma family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_SHEB2
Sequence: MRLTDIEIEQALDNGTIVIEPRPGIEAISGVSVDVRLGGQFRVFKDHTAPYIDLSGPSVEMQAALDRVMSEIIEIPDGEAFFLHPGELALAVTYESVTLPADIVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFYNSGKLPLALRPRMTIGALNFERLNHAVARPYNTRKSAKYKDQQEAVASRISQD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: SSAA1_STAAC
Sequence: MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
What is the function of this protein?
Not known; immunogenic protein.
What are the official names of this protein?
Staphylococcal secretory antigen ssaA1.
What are the subcellular locations of this protein?
Secreted.
Protein: PTTH_BOMMO
Sequence: MITRPIILVILCYAILMIVQSFVPKAVALKRKPDVGGFMVEDQRTHKSHNYMMKRARNDVLGDKENVRPNPYYTEPFDPDTSPEELSALIVDYANMIRNDVILLDNSVETRTRKRGNIQVENQAIPDPPCTCKYKKEIEDLGENSVPRFIETRNCNKTQQPTCRPPYICKESLYSITILKRRETKSQESLEIPNELKYRWVAESHPVSVACLCTRDYQLRYNNN
What is the function of this protein?
Peptides P2K and P6K are presumed to be cleaved post-translationally and may play some unknown physiologically or developmentally important functions.
What are the official names of this protein?
Prothoracicotropic hormone, PTTH.
Protein: ILVC_AERHH
Sequence: MANYFNTLNLRQQLAQLGKCRFMQREEFADGCNVLKGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKAAITEKRASWQKATDNGFAVGTYEELIPTADLVLNLTPDKQHSDVVKTVMPLMKQGAALGYSHGFNVVEEGQQIRADITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWASATGGDRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCYDKLVAEGTDPAYAGKLIQFGWETITEALKQGGISLMMDRLSNPAKLRAFELSEQLKTLMRPLFEKHMDDIIAGEFSRGMMADWAEDDAKLFGWREETGKSAFENAPAFAGKIAEQEYFDNGVVMVAMVKAGVELAFETMVASGIYEESAYYESLHELPLIANTVARKRLYEMNVVISDTAEYGNYLFANAAVPLLREHFMPTLKAGDLGASKAEGQSVDNLALLAANEATRNHPIEKIGQVLRGYMKDMKRIAVGG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: DBR1_ORYSJ
Sequence: MKIAVEGCMHGELDKVYDTLRELEKAEGVKIDLLLCCGDFQAVRNENDLQCLNVKPRFREMKSFWKYYSGQAVAPYPTIFIGGNHEASNYLWELYYGGWAAPNIYFLGFAGVVKFGNIRIGGLSGIYKQQHYHLGHYERPPYNENTIRSVYHVRHYDVLKLMHVKEPLDIFMSHDWPLGITEYGNWQKLIREKRFFEEEVNKRTLGSEPAARLLNKLKPPYWFSAHLHCKFPAVIQHGEGGPTTKFLALDKCLPRRGFLQVIDIPSGPGPHEIQYDEEWLAITRKFNNVFSLTRMPFTMLDEQVDTQDDLQWVRNKLNARGAKPIDFVQTAASYDPSCQASNPSITVHCRNPQTESFLQLLNLPYLLDSSNSYGVSRNESSSQTGQALDSDDIELPDDEDDPADDDD
What is the function of this protein?
Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded.  It thereby facilitates ribonucleotide turnover.  It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis.
What are the official names of this protein?
Lariat debranching enzyme.
What is the protein family that this protein belongs to?
Belongs to the lariat debranching enzyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLVAP_RAT
Sequence: MGLSMDRSPYSRTGDRDRGCWYYLRYFFLFVSLIQFLIILGLVLFMIYGNVHATTESSLRATEIRADNLYSQVVGLSAAQANLSKQLNISTLVKDTVMQQLLTTRREVERINASFRQCQGDLITYINYNRFIAAIILSEKQCQEQLKEGNKTCEALLFKLGEKVKTLEMEVVKEKAVCSKDKDSLLAGKRQAEMQQEACGKAREQQKQDQQVTEEQLRKVQSLCLPLDQEKFQADVLNVWRDSLVYRSLDNIGYHYSLMPEFSSLRRTCESLPGIMTTKVEELARGLRAGIERVTRENGELRRQKLELERAIQGEREARTRAGTEAQARETQLRTECARQTQLALEEKAALRTQRDDLERQLEARKRELEQLRTEVDVRISALDTCVKAKSLPAIQPRLPGPPPNPPPIDPASLEEFKKRILESQRPPLVNPAVPPSG
What is the function of this protein?
Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae.  It is also required for the formation of stomata of caveolae and transendothelial channels.  Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs.  Plays a specific role in embryonic development.
What are the official names of this protein?
Plasmalemma vesicle-associated protein, Plasmalemma vesicle protein 1, PV-1, gp68.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Membrane, caveola; Single-pass type II membrane protein. Cytoplasm, perinuclear region. Note=Membrane-associated protein of caveolae (PubMed:10366592). Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels (PubMed:10557298). Also colocalized with CAV1 in perinuclear region (PubMed:15640522).
Protein: RTL1_HUMAN
Sequence: MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGSGVRGEAGPASGPAQEKKEPPSGPLQEMEELPTDLLQDMEEPSSGPRKEIEDPPNDLLQDLEESCNGSHQARGDPLSGASDRMKEASVNPSGAREEQEAHTDLKESGREETPQEQNQTEHSTAELMAMVRSIISLYFRMQDLKEQQRVAEEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSYPRMFYNDRLRVGYVINHLSGLALEWAKALLQENSPLIGDFPAFLEAMSEVFEYRQALRVAEEAMFTIRQGGRSATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLFRVPQPDSLDSLIVLILQIEEKLAERRAMLRLPPEARPRNLTWIDSPAPERWMVSSWLPSEVHPDINRAHLFLLLMVRVNPYHSVAVQALVDSGADGNFMDEKFAQEHYVELYEKPYPQPVQSVDGSLIGNEPVWLYTEPLVCIHQNHQESIEFDIVPSPNFSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLKNCFRPPPPCIALERHGMSLLPGLPHPYSDLADVFNPKEADDETSDQPSSDGSDDLSESEPSELQQAGDSDHSETFYECPSTAPWEPVGARMQERARLQEEYWDLQDMLTNRQDYIQMIPELFDQLHGAEWFTKLELRGTIVEESVNGHRTEDVWKAAFGLELEEMKSYQPFALSPDPIIPQNVIHFILKDMLGFFVLSYGQEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQFHRQTVEFLGFVVTPKGVKLNKNVMTIITGYPTPGSKLSLRNFIEFVFPYRHFVERFSIIAEPLVRQLLSSYQFYWGVEEQEAFECLKRAFRKAPLLHHPKPQNPFYLETGVTGTALHASLIQIDDQTGKRACCAFYSRNISPIEVEYSQAEMKILPIRAAFMVWCRYLENTEEPIMILLNTEDLASLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDGGRALPPVRNLRWRRAFQRNTAARQTLLLASRGFPRDPSTESGEEENEEQDELNEQILRQELLAMIPIDQILNSFLAHFSMAQIRAVILHFFRGLLYWKNTLALAAILVLLRVRQCLSLRPAPAMRVARPQPQRSLRLILDSSLIAGSSITTAITQLLTQMPALVGANTIPAQELAELFLGPGRWQRNALHSQAHRGLQFTPGFWLTLCEFFGVRVTPQEGHLPALRQNRYLELHVVGDEDVVLREALQDDLQRYRQCGLHDGLQDTSQDKQDNDVQEAPPSHTAATHPPRPRHLMDPQVLEFLGSRLLHIHSADGQLHLLSREQAARALSQFLTLIYRRALPIPAWESQPREQARLEELPDEDEDANLD
What is the function of this protein?
Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta.
What are the official names of this protein?
Retrotransposon-like protein 1, Mammalian retrotransposon derived protein 1, Paternally expressed gene 11 protein, Retrotransposon-derived protein PEG11.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y087_MYCPN
Sequence: MTLIYVPTTLNLIDSFNYSESIYKWGDYFFRHLESRDFYFSNFGFISLFLLLFVIPTITLTTLGCFLFSYLRFTDINKIKIQIYSLLTVFIFIDVFGLVVSVLFGYLLPLAFDSLPFSVNLTREVFLSLAMIVIFANSVIFTLRQKRNID
What are the official names of this protein?
Uncharacterized protein MPN_087.
What is the protein family that this protein belongs to?
To M.pneumoniae MPN_085 central region.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIBA_SHEB9
Sequence: MSIKYVATSKLPTPWGVFAMHGFEDTESGKEHVALTFGTLSADEPVLGRIHSECLTGDALFSLRCDCGFQLQAAMQNIAETGSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQLGFEADMRKYDMIKPMLEQIGVKHVRLMTNNPRKVKAMKEFGIEVVERVPLQVGKNRYNEAYLKTKSTELGHMMSEYHFMDENK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: RL2_BACFR
Sequence: MAVRKFKPTTPGQRHKIIGTFEEITASVPEKSLVYGKKSSGGRNNEGKMTMRYLGGGHRKVIRIVDFKRNKDGVPAVVKTIEYDPNRSARIALLFYADGEKRYIIAPNGLQVGATLMSGENAAPEIGNALPLQNIPVGTVIHNIELRPGQGAALVRSAGNFAQLTSREGKYCVIKLPSGEVRQILSTCKATIGSVGNSDHGLESSGKAGRSRWQGRRPRNRGVVMNPVDHPMGGGEGRASGGHPRSRKGLYAKGLKTRAPKKQSSKYIIERRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PYREL_METAR
Sequence: MKNVNDLIEKAIELRNRGLRSGEIADELNISRETATWLLTRARKETGAQAPKDIFIDWSTIGKSSSRLMLIATCMADMVEEVLNEMDTNVDVVVGIALSGVPLANVVAYQYGVDLAVIHPGKHRSDDTGKHHQMQPTVSENYANVKGKRCVIIDDVITTGSTMEETIKLIEDQGGEAVAIAVIIDKRGADTISNVPVKHLIRIGRVD
What are the official names of this protein?
PyrE-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: TRHO_WOLTR
Sequence: MSFVIATFYHFVKLSNYYDMKDEIKAACDNFELKGTILLAEEGINATISGERNAINKIFNFLCSDYRLKDLTWKESAAKYQPFSKMKVRLKREIVNLGVSNLDTSLRGKYIDPDHWDDFISQPDVLVIDTRNEYEVKLGKFKNAINPYIQYFREFPQWAKSFSKNKNLKVAMYCTGGIRCEKSTAYMKSLGFNDVYHLKGGILSYLERTHNKNGNWEGECFVFDDRIAINSSLAPSNKIKCIFCSNQVSADELKSVSRGQVVCSDCNPS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CRYGS_HUMAN
Sequence: MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin S, Beta-crystallin S, Gamma-S-crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: RPOA_COLP3
Sequence: MQGSVTEFLRPRLVGIETVSPRRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDIIEILLNLKGLAVILEGKNEAVLTVTKSGEGPVTAADIQHDGDVTIANPDHVICTLTGEGSISMRIKVEMGRGYVPASARRDAEEEDRAIGRLLVDASFSPVVRIAYDVDSARVEQRTDLDKLVLDMETNGTLDPEEAIRRASTILAEQLDAFVELRDIKEVEQVEEKPLFDPILLRPVDDLELTVRSANCLKAEAIQYIGDLVQRAEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPESIVDND
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: NCAP_BUNSH
Sequence: MSDLVFYDVASTGANGFDPDAGYMAFCVKYAESVNLAAVRIFFLNAAKAKAALSRKPERKANPKFGEWQVEVVNNHFPGNRNNPINSDDLTIHRLSGYLARWVLEQYKENEDESRRELIKTTIINPIAESNGVRWDSGAEIYLSFFPGTEMFLETFKFYPLTIGIYRVKQGMMDPQYLKKALRQRYGSLTADKWMSQKVTAIAKSLKEVEQLKWGRGGLSDTARSFLQKFGIRLP
What is the function of this protein?
Encapsidates the genome protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication.  Seems to participate in the nuclear relocalization of host PABP1, thereby inhibiting host cellular translation (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Internal protein of virus particle.
Protein: FABA_NITOC
Sequence: MIRPSAFSYEDLLQCGRGEMFGPGNAQLPMPPMLMFDRITYISDEGGAFGKGEINAEMEIKPDSWFFNCHFPSDPVMPGCLGLDAMWQLLGFYLAWRGGPGHGRALGSGEVKFTGQVTPKNKLVTYHINLKRVIMRKLVMGIADGIMAVDGREIYLAKDLRVGLFVSTDSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U633A_HUMAN
Sequence: MRKLRLRASNPGPSGAPGTRRHFSTSGGGHHCGRRWLRRVRRSRSQTPSCQNLDPNPPIARFPLPLERISEVPRRACLHGRDASSVWPPPERSD
What are the official names of this protein?
Putative UPF0633 protein MGC21881.
What is the protein family that this protein belongs to?
Belongs to the UPF0633 family.
Protein: QUEF_PROM3
Sequence: MSSTEAQASKPLYGERVIAEGELICFDNPRPERPYEISIELPEFTCQCPFSGYPDFAVLRLLYQPGPRVIELKAIKLYVNSYRNCSISHEEAANKILDDLVVACDPVWMQLEADFNPRGNVHTVVRVSHGSRQPC
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDOC_RAT
Sequence: MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQEKGILVGIKVDKGVVPLAGTDGETTTQGLDGLLERCAQYKKDGADFAKWRCVLKISDRTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQFVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCSLPRPWALTFSYGRALQASALSAWRGQRDNAGAATEEFIKRAEMNGLAAQGKYEGSGDGGAAAQSLYVANHAY
What are the official names of this protein?
Fructose-bisphosphate aldolase C, Brain-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: USP1_PINMG
Sequence: MQFRPSIALVLSIVGILSLEISWTDGCTCFMETRREKCQRSTFGFIGYPYFAGRTNIGGMEYNRFCFFIVRIHKGLSVVFGEPCVYSSVSSAACGTGFYSGSLSIVNGYIESGVKQVNLCGWNERWRSVPSFVKFMFLTQPNWCYA
What are the official names of this protein?
Uncharacterized shell protein 1, Prism tissue inhibitor metalloproteinase protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: BETB_RHILW
Sequence: MKAQPKASHFIDGEYVEDTDGTVIESLYPATGEVIARLHAATPAIVEKAIAAARRAQPEWAAMSPMARGRILKRAADIMRERNRALSELETLDTGKPIQETIVADPTSGADAFEFFGGVAPAGLNGSHIPLGQDFAYTKRVPLGVCVGIGAWNYPQQIACWKAAPALISGNAMVFKPSENTPLGALKIAEILHEAGLPKGLFNVIQGDRDTGPLLVNHPDVAKVSLTGSVPTGRRVAAAAAGNLKHVTMELGGKSPLIVFDDADLDSAVGGAMLGNFYSTGQVCSNGTRVFVQKGIKTEFLKRLKARTEAMLIGDPLDEATQIGPMVSWAQREKVVAYIEKGKAEGATLVAGGGIPNNVSGEGYYIQPTVFADVTDDMTIAREEIFGPVMSVLDFDDEDEVIARANASEFGLSGGVFTADLSRAHRVVDRLEAGTLWINAYNLAPVEIPFGGSKQSGFGRENSLAALEHYSELKTVYVGMGPVQAPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PRS52_MOUSE
Sequence: MKRWKDRRTGLLLPLVLLLFGACSSLAWVCGRRMSSRSQQLNNASAIVEGKPASAIVGGKPANILEFPWHVGIMNHGSHLCGGSILNEWWVLSASHCFDQLNNSKLEIIHGTEDLSTKGIKYQKVDKLFLHPKFDDWLLDNDIALLLLKSPLNLSVNRIPICTSEISDIQAWRNCWVTGWGITNTSEKGVQPTILQAVKVDLYRWDWCGYILSLLTKNMLCAGTQDPGKDACQGDSGGALVCNKKRNTAIWYQVGIVSWGMGCGKKNLPGVYTKVSHYVRWISKQTAKAGRPYMYEQNSACPLVLSCRAILFLYFVMFLLT
What is the function of this protein?
Probable serine protease.
What are the official names of this protein?
Serine protease 52, Testicular-specific serine protease 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GLYA_PROM2
Sequence: MNILQNLKDSDPVISNFINSEKNRQETHLELIASENFASIAVMQAQGSVLTNKYAEGLPQKRYYGGCEFVDEIEELAINRAKKLFNANWANVQPHSGAQANAAVFLSLLKPGDTIMGMDLSHGGHLTHGSPVNMSGKWFNAVHYGVNKETSELNFDEIREIALETKPKLIICGYSAYPRTIDFESFRNIADEVGAFLMADIAHIAGLVASKLHPNPIPYCDVVTTTTHKTLRGPRGGLILCKDAEFGKKFDKSVFPGTQGGPLEHIIAAKAVAFGEALQPDFVNYSQQVIKNAKVLASTLINRGINIVSGGTDNHIVLLDLRSINMTGKIADLLVSEVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFNENAFEEVGEIIADRLLNPNDSLIESQCKERVLSLCNSFPLYEGKLEASIK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_BEAHI
Sequence: MTNIRKTHPLMKIINHSFIDLPTPSNISSWWNFGSLLGICLILQIMTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYTYMETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIIVALVMVHLLFLHETGSNNPTGLESNADKIPFHPYYTIKDILGAFLLVFFLIFLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSVPNKLGGVLALILSILILALLPHLHMSKLRSLMFRPISQICFWLLVSDILILTWIGGQPVEYPFITIGQVASILYFIIIIILMPASTMIEDKILKWD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.