PharMolix/UniProtQA huggingface dataset:
Protein: NU3M_GADMO
Sequence: MNLISTVILIASALSLILILVSFWLPQLSPDYEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLSNPTLTFMWATSVLALLTLGLIYEWLQGGLEWAE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TRES_MYCS2
Sequence: MEEHTQGSHVEAGIVEHPNAEDFGHARTLPTDTNWFKHAVFYEVLVRAFYDSNADGIGDLRGLTEKLDYIKWLGVDCLWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFVTLLDAAHRRGIRIITDLVMNHTSDQHEWFQESRHNPDGPYGDFYVWSDTSDRYPDARIIFVDTEESNWTFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMLDVLRFWLDLGIDGFRLDAVPYLFEREGTNCENLPETHAFLKRCRKAIDDEYPGRVLLAEANQWPADVVAYFGDPDTGGDECHMAFHFPLMPRIFMAVRRESRFPISEILAQTPPIPDTAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPRMKANVGIRRRLAPLLENDRNQIELFTALLLSLPGSPVLYYGDEIGMGDIIWLGDRDSVRTPMQWTPDRNAGFSKATPGRLYLPPNQDAVYGYHSVNVEAQLDSSSSLLNWTRNMLAVRSRHDAFAVGTFRELGGSNPSVLAYIREVTRQQGDGGAKTDAVLCVNNLSRFPQPIELNLQQWAGYIPVEMTGYVEFPSIGQLPYLLTLPGHGFYWFQLREPDPEPGAQQ
What is the function of this protein?
Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation (PubMed:15511231, PubMed:18505459, PubMed:20118231, PubMed:21840994).  Maltose is the preferred substrate (PubMed:15511231, PubMed:18505459).  To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose (PubMed:18505459).  TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P) (PubMed:20118231, PubMed:27513637).  Might also function as a sensor and/or regulator of trehalose levels within the cell.  Thus, when trehalose levels in the cell become dangerously low, TreS can expedite the conversion of glycogen to maltose via its amylase activity and then convert the maltose to trehalose; but this enzyme also can expedite or promote the conversion of trehalose to glycogen when cytoplasmic trehalose levels become too high.  Is also able to catalyze the hydrolytic cleavage of alpha-aryl glucosides, as well as alpha-glucosyl fluoride in vitro.
What are the official names of this protein?
Trehalose synthase/amylase TreS, Maltose alpha-D-glucosyltransferase, MTase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. TreS subfamily.
Protein: COBS_TRIV2
Sequence: MVKLLLLNLLASIIFYTSIPLPYIKGLDFQKVARLVPMVGLIIGVILGLLDGGMNYLGMPVLTRSALVVALWIFITGGLHLDGAMDTADGLAVGDPERRLQVMADSATGAFGAMSAIAILLLKTSALTEIGEYRWLVLMAACGWGRWGQQVAIACYPYLKATGKGAFHKQAIRSYKDLLPGLCLMVAVSSLFWLVNNHHLLITVVGLITGSAIASLTAAWFNHKLGGHTGDTYGAVVEWTEALFLCVLTILT
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PVK1_MANRE
Sequence: QGLISFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, Manre-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACCA_CLOAB
Sequence: MENSQELTPWQRLTIARMLERPTSLEYIDLIFDSFMEFHGDRAFGDDAAIVGGVAEFNGMPVTVIGQQKGRNTNENIKRNFGMPSPEGYRKALRLMKQAEKFNRPLICFVDTSGAYCGVEAEQRGQGEAIAKNLISMANLKIPVISVVIGEGGSGGALAMAVADEVWMLENSVYSLLSPEGFASILWKDSSRAKEAAEVMKITADDLKGYGIIDKVIKEPDGGAQNDITMVANALRENLKKAIEGLSSTGINELLDNRYNKFRQIGKFIENEDN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_BURP1
Sequence: MPKMKTKKSAAKRFVVRPGGTVKRGQAFKRHILTKKTTKNKRHLRGATAVHDSDLNSVRAMLPFA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PUR1_PYRHO
Sequence: MRGEIMKEKCGIFGAYSQDATKKTYYGLMALQHRGQEGAGISVWDGDIRTVKGHGLVSEVFKGGSIRRLNGNPVIGHVRYSTSGSLSEVQPLEVECCGYKVSIAHNGTLTNFLPLRRFYESRGFKFRSSIDTEVIAVSFLNHYSELKDEFEAMSRVFEEVKGAYSVLMLFNGKLIAVRDPVGFRPLSFGAGDGYYFSSEDSALRMFCTNIRDVSPGEVIVVKDGEAESKIVGRSEHAYCVFEYIYFARPDSIINGISVYWARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGREIKVRLKLSPVKEVIKGRRIVLVDDSIVRGTTMKNIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWKSIEEIKKEIGADSLAYLSVEGLKRAIGTDKLCMACLTGNYPEWAFDFKV
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: ISPD_CHLP8
Sequence: MKTVAIIAASGVGKRMKLDGGMSKQMIEIGGHTVIWHTMKAFQDAESVDAVYIATKSDSIEPFKQLARENGFTKIHSIIEGGKERQDSIRNCMDLIEEEIESSGVMPDAILVHDGARPFIQPEEIDEIARISAEHGACVPATKPKDTIKYIGRTPEVFGETLDRSRLLQVQTPQGFTPAKLIEAHRKAASDGVYATDDAALVERYFPEQEIHVYEMGYHNIKITTPEDVPVGEAILAGLKARKSEN
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PJA2_RAT
Sequence: MSQYTEKEPSVMDQDSSKAAWPRAAGGYQTITGRRYGRRHAYVSFKPCMTRHERSLGRAGDDYEVLELDDVAKENTAGSSSLDQVHPSLPSETTVEKSETEIPTCGPALNQSTESNPSVATVCHSEEVRETLDSSTNLQNHAERECTPAVCNASSVQNGIVLVHTDSYDPDSKHDENDSLQLCAQAVEGGRRQKVLGNAVFELENGEVERYADLCPSVPSLSGEIREESEELGSALLEKNSAGDAEAVHQDGQEFQRSSEDGIVRKRRQDDTDQGRQTENSTEDADCVPGHVEQNTSERANHHGSSPEQVVRPKVRKVISSSQVDQESGFNRHEAKQRSVQRWREALEVEECSSDDPIIKCDDYDGDHDCMFLTPSYSRVTPREAERHRATAENGATASGRQEARENAFWNACGEYYQLFDKDEDSSECSDGEWSASLPHRFSGTEKDQSSSDESWETLPGKDENEPELQSDSSGPEEENQELSLQEGEQTSLEEGEIPWLQYNEVNESSSDEGNEPANEFAQPEAFMLDGNNNLEDDSSVSEDLDVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDGLPETLVLEDHTAIGQEQCCPICCSEYIKDDIATELPCHHFFHKPCVSIWLQKSGTCPVCRRHFPPAVIDASAAASSEPDLDASPANDNAEEAP
What is the function of this protein?
Has E2-dependent E3 ubiquitin-protein ligase activity.  Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation.  Essential for PKA-mediated long-term memory processes (PubMed:21423175).  Through the ubiquitination of MFHAS1, positively regulates the TLR2 signaling pathway that leads to the activation of the downstream p38 and JNK MAP kinases and promotes the polarization of macrophages toward the pro-inflammatory M1 phenotype.  Plays a role in ciliogenesis by ubiquitinating OFD1 (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase Praja-2, Praja2, RING-type E3 ubiquitin transferase Praja-2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Synapse. Postsynaptic density. Note=Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus. Expressed in the postsynaptic density region of synapses. Colocalizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane (By similarity).
Protein: RL6_SYNWW
Sequence: MSRIGKKPISLPAGVEVSIKDNAISVKGPKGVLEWALPEGITVVQEGNELVVKRPSDIKQHRAMHGLSRALIANMVQGVSAGFEKKLELVGVGYRAQMQGKKLVISIGFSHPVEVEPPEGIEFEVPAVTRITVKGIDKQLVGNTAAHIRAIRKPEPYKGKGIKYENEVIRRKAGKAGGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: END4_SALTY
Sequence: MKYIGAHVSAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPDIWAEEIAWLKAQQIAEAMA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL13_FRAP2
Sequence: MKTFTAKPSDIKRQWLLIDATDKTLGRLASEVAMILRGKNKPEYTPSMDTGDYVVIINAEKVAVTGNKRKGKIYHHHTGYIGGIKSISFEKLIATHPERAIEKAVKGMLPRSPLGRAMYKKLKVYAGENHPHTAQQPQAHNI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TKTP_CUPNH
Sequence: MNAPERIDPAARCANALRFLAADAVELARSGHPGAPMGMAEMAEVVWRRHLRHNPANPAWPDRDRFVLSNGHASMLQYALLHLTGYDLPMSQLRQFRQLHAVTPGHPEVDVTPGVETTTGPLGQGLANAVGMALAEKLLAATFNRPGFDIVDHHTYVFLGDGCLMEGLSHEACSLAGTLGLGKLICLYDDNGISIDGEVAGWFADDTPKRFAAYGWHVIADVDGHDAHALDAALHEAKAERDRPTLICCRTVIGKGAPAKAGGHDVHGAPLGAPEIAAMRTALGWEAEPFTVPADVADAWDARAQGAAREAEWEARFVSYCAAHPELAEEFVRRANGRLPEGFDAELMALLDAPSPLQGKIATRKASQLCLEALTPALPELLGGSADLTGSNLTNVKASVWVNHAGHGNYVSYGVREFGMAAVMNGIALHGGLIPYGGTFMTFSDYSRNAIRMAALMRLRVVHVLTHDSIGLGEDGPTHQPVEHAASLRLIPNNQVWRPCDGAETAYAWLAALQRENGPTCLVLSRQALMPFERDAAQRADIARGGYVLRDVPAPRVVLIATGSEVEIAARAALDLADAGIAARVVSMPCVELFYAQDAAYRDSVLPPGLPRISVEAGATWYWRGVVGEQGLALGIDSFGESAPAEALYQHFGLTPAHVAAAARVLLEDA
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase, plasmid, TK.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: PYRDA_STRP3
Sequence: MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVTKTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVVGLSPTETETILKVIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTKPLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGIGGDYIKPTALANVHAFYKRLKPSIHIIGTGGIKTGRDAFEHILCGASMVQIGTALHQEGPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Putative dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADC_HELPJ
Sequence: MEIKTFLECALKEDLGHGDLFERVLEKDFKATAFVRAKQEGVFSGEKYALELLQMTGIECVQNIKDKERFKPKDTLMEIRGDFSMLLKIERTLLNLLQHSSGIATLTSRFVEALNSPKVRLLDTRKTRPLLRIFEKYSVLNGGASNHRLGLDDALMLKDTHLKHVKDLKSFLTHARKNLPFTAKIEIECESFEEAKNAMSAGADIVMCDNMSVGETKEIAAYREAHYPFVLLEASGNISLESINAYAKSGVDAISVGALIHQATFIDMHMKMA
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Probable nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: MIAB_BURPS
Sequence: MTKKVYVKTFGCQMNEYDSDKMVDVLNAAEGLEKTDTPEDADIILFNTCSVREKAQEKVFSDLGRVRELKEAKPDLLIGVGGCVASQEGASIVARAPYVDLVFGPQTLHRLPQMIDARRESGRAQVDITFPEIEKFDHLPPARVEGPSAFVSIMEGCSKYCSYCVVPYTRGDEVSRPLDDVLTEVAGLADQGVREVTLLGQNVNAYRGAIAAGSAEIADFATLIEYVADIPGIERIRYTTSHPKEFTQRLLDVYAKVPKLVDHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPNLSLSTDIIVGFPGETDADFDKTMALVHEMSYDTSFSFIYSPRPGTPAANLADDTPRELKLKRLQHLQATIEENVARISQSMLGKVERILVEGPSRKDPNELAGRTENNRVVNFPAPSAAHPRLIGQMIDVKINHAYPHSLRGELVLAHGDASAATH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAT_BACAN
Sequence: MSSKTLAKFLEENLEDLKSKGLYNVIDPLESSNGPIITIGGKEYINLSSNNYLGLATDSRLQEAAIGAIHKYGVGAGAVRTINGTLDLHIKLEETIAKFKHTEAAIAYQSGFNCNMAAISAVMDKNDAILSDELNHASIIDGSRLSKAKIIVYKHSDMEDLRQKAIAAKESGLYNKLMVITDGVFSMDGDVAKLPEIVEIAEELDLMTYVDDAHGSGVLGKGAGTVKHFGLSDKVDFQIGTLSKAIGVIGGYVAGKQNLIDWLKVRSRPFLFSTAVTPADAAACMRSIEILMESTELHDRLWENGRYLKQGLKELGFNIGESETPITPCIIGDEVLTQEFSKRLNEEGVYAKSIVFPTVAKGTGRVRNMPTAAHTKEMLDEAIRKYEKVGKEMGII
What are the official names of this protein?
Putative pyridoxal phosphate-dependent acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: RCN3_HUMAN
Sequence: MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGNFQYDHEAFLGREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVSAAWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAEPGEEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKAEILGNWNMFVGSQATNYGEDLTRHHDEL
What is the function of this protein?
Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891).  Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (By similarity).  By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (By similarity).  Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891).  This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634).
What are the official names of this protein?
Reticulocalbin-3, EF-hand calcium-binding protein RLP49.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: CYB_URSMA
Sequence: MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVHYGWVIRYVHANGASMFFICLFMHVGRGLYYGSYLFSETWNVGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLTLALATLVLFSPDLLGDPDNYIPANPLSTPPHIKPEWYFLFAYAILWSIPNKLGGVLALIFSILILALIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UVRC_FRATM
Sequence: MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRVNSYFSKGAKDSKTLMMVEQIARIEITITPSDYEAYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCENSYYKSRVRPCLQYQIKRCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISAKMYQASEDMEYEKAQVYRDQLVVLRKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKNIILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLELEKDIKRIECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKGIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQAEAVFREYGIQDKVQLVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSIIEEIEGVGSKRRKALLRYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLR_ECOL6
Sequence: MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSLYAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK
What is the function of this protein?
Involved in the repression of the expression of the mannitol mtlADR operon.  Does not bind the operator/promoter regulatory region of this operon.  Therefore, seems to belong to a new class of transcription factors in bacteria that may regulate gene expression indirectly, perhaps as a part of a larger transcriptional complex.
What are the official names of this protein?
Mannitol operon repressor, Mannitol repressor protein.
What is the protein family that this protein belongs to?
Belongs to the MtlR/FumE family.
Protein: KAD_FRATT
Sequence: MRIILLGAPGAGKGTQAKIIEQKYNIAHISTGDMIRETIKSGSALGQELKKVLDAGELVSDEFIIKIVKDRISKNDCNNGFLLDGVPRTIPQAQELDKLGVNIDYIVEVDVADNLLIERITGRRIHPASGRTYHTKFNPPKVADKDDVTGEPLITRTDDNEDTVKQRLSVYHAQTAKLIDFYRNFSSTNTKIPKYIKINGDQAVEKVSQDIFDQLNKR
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN672_HUMAN
Sequence: MFATSGAVAAGKPYSCSECGKSFCYSSVLLRHERAHGGDGRFRCLECGERCARAADLRAHRRTHAGQTLYICSECGQSFRHSGRLDLHLGAHRQRCRTCPCRTCGRRFPHLPALLLHRRRQHLPERPRRCPLCARTFRQSALLFHQARAHPLGTTSDPAAPPHRCAQCPRAFRSGAGLRSHARIHVSRSPTRPRVSDAHQCGVCGKCFGKSSTLTRHLQTHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACGDCGRCFSESSTLLRHRRSHQGERPHACATCGKGFGQRSDLVVHQRIHTGEKPFACPECGRRFSDRSDLTKHRRTHTGEKPYRCELCGKRFTCVSNLNVHRRNHAGHKPHKCPECSKAFSVASKLALHRKTHLGERPAECAECGKCFSHSRSLSQHQRAHTRARTAAAVAIQSAVGTALVFEGPAEQEKPGFSVS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 672.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: G1091_PHOV8
Sequence: MIKNLSTFFVGIALSCLAGCTPIPKETTATKEYAPLEVPVPERPAGQQDVIELTTPKLDTVRVGFIGLGMRGPSAVERWTHIPGTKIVALCDLLPENAEKAQKIVTNAGMEAPALYSGSEDAWKQLCERNDIDLVYIATDWKHHTEMGIYAMEHGKHAAIEVPAAMSLDEIWALINTSEKTRKHCMQLENCVYDFFELTTLNMAQKGLFGEVLHVEGSYIHNLEEFWPYYWNNWRLDYNREFRGDVYATHGLGPACQLLNIHRGDRMKTLVAMDTKAVTGPELVKQYQKEEAPDFQNGDHTMTFIRTENGKTIHIQHDVMNPRPYSRMYQLTGTKGFANKYPIEQYCFRPDQIDSTSIPDHENLSMHSAVPEKVKEALMSQYKHPIHQELEETAKKIGGHGGMDFIMDYRLVYCLRNGLPLDMDVYDLAEWCCMADLTRLSIENGNAPVAVPDFTRGNWNKVDGYHHAFAQ
What is the function of this protein?
Glycosidase.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein 1.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CL141_CAEEL
Sequence: MRSSSTLLIAFGLFLASMSVEAIIRPGYGSGGHRPPSSYHGGHHNDDDCTTKPPKSTSTPSTSTSTPTTTTTTTTTTTTTPTTTTTTTTTTTPEPTTTKVKVCPQGYTSFLRTPAADNSFTSEWCMQLIWSPRQPMPINNASALCQASNTEAVVTTFANEEELNVFSLQMAQQFDRVGPATRGAIAVDGRRIAACVSRDRGILDSEECNGTNSFVMVDKHTSPGFTWSKWATNEPSANAWTYDIEQCIQFTVYPALTGPGDNPYNMLNRNNKFNDIYCNMDKAPNEPTNTAYWNFGALCGVLPS
What are the official names of this protein?
C-type lectin domain-containing protein 141.
Protein: MED8_NEOFI
Sequence: MASLNQDQIKTLEQSRQRLVQLTRSLASLIGSLNQSDPLPSWSSLQSQAGIISNNLLSISEHLSDNKDLLSALVAYPGPSYPGRTQAPTLEQLLRTKLDPRVEDWVSRGRRAGASALEDRGALSESALAELWDWAPVEANQEARRRNWGGNFTLEEREMGIQNVVTGLRRQLEDEDEEESESESEEEGEGEEEEMEVVGVRRRSGAGAGLEFDIAAPTPGSRQQQQQKAAGPAVPLEDILRYMTTGIPPTQR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8, Mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS15_PROM2
Sequence: MSLDTAEKQKLIETHQVHPTDTGSAEVQVAMLSKRISKLSDHLQGNIHDFSSRQGLLKMIGKRKRLLSYIKDKNIQRYQELVKKIGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.