PharMolix/UniProtQA huggingface dataset:
Protein: LAMC2_HUMAN
Sequence: MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLSRAKTQINSQLRPMMSELEERARQQRGHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ
What is the function of this protein?
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.  Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.
What are the official names of this protein?
Laminin subunit gamma-2, Cell-scattering factor 140 kDa subunit, CSF 140 kDa subunit, Epiligrin subunit gamma, Kalinin subunit gamma, Kalinin/nicein/epiligrin 100 kDa subunit, Ladsin 140 kDa subunit, Laminin B2t chain, Laminin-5 subunit gamma, Large adhesive scatter factor 140 kDa subunit, Nicein subunit gamma.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Protein: GLK_ECOHS
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What is the function of this protein?
Not highly important in E. coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDH2_MOUSE
Sequence: MLRAALTTVRRGPRLSRLLSAAATSAVPAPNHQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAARAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEGVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQENVYDEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANDSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS
What is the function of this protein?
Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage.
What are the official names of this protein?
Aldehyde dehydrogenase, mitochondrial, AHD-M1, ALDH class 2, ALDH-E2, ALDHI.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y1984_AZOVD
Sequence: MMKGGMAGLMKQAQLMQEKMQKLQEEIANAEVTGQSGAGLVSVVMTGRHDVRRVTLDDSLMQEDKEVLEDLIAAAVNDAVRKIEQNNQEKMAGMTAGMGLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Avin_19840.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS3A_LENED
Sequence: MAVGKNKRLSKGKKGIKKKVVDPFSRKDWYDIKAPSIFDVRNVGKTLVNRSQGLKNANDSLKGRIIEVSLGDLNKEEEQSFRKIKLRVDEVQGKNCLTNFHGMDFTSDKLRSLVRKWQTLIEAHVDVKTTDGYLLRLFAIGFTKRRPTQVRKTTYAQSSQVREIRKKMFEIMTREATNCDLKELVQKFVPEAIGREIEKASRSIYPLQNVYVRKAKILKAPKFDVSKLMELHGESTDETGTKIAKDFKEPEVLESV
What are the official names of this protein?
40S ribosomal protein S1, Protein cyc07.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNUT1_RAT
Sequence: MGSSKKHRGEKEAAGTTAAAGTGGTTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGAERGSGRRGAEAEARSGAHGRERSQAEPSERRVKREKRDEGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVAADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVVLTLKDKGVLQEGEDVLVNVNMVDKERADKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRERELEEIRTKLRLQAQSLNTVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLGEDQTQDGDFGSRLRGRGRRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPSGPPELEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVLEIVKKLESRQRGWEEEEDPERKGTIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQHQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK
What is the function of this protein?
Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome.  May also bind to DNA.
What are the official names of this protein?
U4/U6.U5 tri-snRNP-associated protein 1, Squamous cell carcinoma antigen recognized by T-cells 1, SART-1, rSART-1.
What is the protein family that this protein belongs to?
Belongs to the SNU66/SART1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMO_MAGSA
Sequence: MSQTNPKVGIVSLGCSKALVDSERILTKLRAEGYDISGSYDGADVVIVNTCGFLDSARAESLEAIGEALAENGKVIVTGCMGGDEKAIRSAHPSVLAVSGPHQYQAVVEAVHAAIPPLHDPKLSLVPPEGLHLTPHHYAYLKISEGCNNSCSFCIIPDIRGPLMSRPAADVLGEAERLAEAGVRELLVISQDTSAYGLDLRHAESTWRGRPVRAHLTDLASALGELGIWIRLHYVYPYPHVDEIIPLMAEGKILPYLDIPFQHASPNVLKAMRRPANQEKVLGRIRSWRETCPDLTLRSTFIVGFPGETEEDFDSLLGWLEEAQLDRVGCFKYEDVKGAPANAFADQVDEDVKEERHQRFMEAARQIADERGAAKEGTRIEVIIDEVDEEGAIGRSKADSPEVDGAVFMNGETDLEPGDLVIVEVEAAEDYDLWGDVVERLPPPRPRR
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MZT2_DANRE
Sequence: MPSAPDSPSLSVNVSGNVQKYSIKKKKVLNAEETELFELTQAAGVVIDQEVFKIIVDLLKMNVAPLAVFQTLKTMCAGQKVSETSTGDASSTSHTTAVPTESRVRSKMSSGQGEKSARESSSQRVPRQVSATRGQKSTKSSGSSSSSSQLTSN
What are the official names of this protein?
Mitotic-spindle organizing protein 2, Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2.
What is the protein family that this protein belongs to?
Belongs to the MOZART2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
Protein: NDUC2_GORGO
Sequence: MIARRNPEPLRFLPDEARSLPPPKLTDPRLLYIGFLGYCSGLIDNLIRRRPIATAGLHRQLLYITAFFFAGYYLVKREDYLYAVRDREMFGYMKLHPEDFPEEDKKTYGEIFEKFHPIR
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 subunit C2, Complex I-B14.5b, CI-B14.5b, NADH-ubiquinone oxidoreductase subunit B14.5b.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFC2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: PEPE_SALHS
Sequence: MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQTWDEYTDKTAEVLAPLGINVTGIHRVADPLAAIEKAEIIIVGGGNTFQLLKESRERGLLAPMADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALDLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGEEAVALEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_ACIBT
Sequence: MRDKIRLVSSAGTGYFYTTTKNKRTMPEKMEIKKFDPKIRQHVIFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RSMJ_PSEU2
Sequence: MIEQQAGSRIRVEALAVGGQEQAAQWAQRLGLPLTDAHADFALQLTDEGLQLQQLGDDAPGAVRVDFVEGAVAHRRLFGGGTGQMIAKAVGIQPGIRPSVLDATAGLGKDAFVLASLGCDMSLIERQPIIAALLEDGLARGRGDRDVGSIIARMRLLTGNSIDLIRAWTGEPPQVIYLDPMFPHREKTALVKKEMRLFRPLVGDDMDAPALLEAALALATHRVVVKRPRKAPCIDGLKPGYALDGKSSRYDIYPKKALKPKAATDESGA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_VIBA3
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAQRYAEEGADELVFYDITASSDGRVVDKSWVKRVAEVIDIPFCVAGGIKSAEDAARILEFGADKVSINSPALANPQLITDLADKFGVQCIVVGIDSYFDKETGKYQVYQFTGDEARTKATKWETKDWVQEVQKRGAGEIVLNMMNQDGVRNGYDIDQLNMVRSVCNVPLIASGGAGAMEHFAEAYKKTNVDGALAASVFHKQIINIGELKQYLKQQDVEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDIP1_DICDI
Sequence: MGQDNINLNKVDGQPSSPPQEQQQQQQYPPQGYPQQQQYPPQQGYPPQQYPPQQGYPPQQYPPQQGYPQQQPPQQYPAPVGAPQQPYMATQQVVVQQVYVQPTFGVVPVDCICQHCQTRMSTKTSYKSGSMVWLVCVLLIIFGCWLGCCLIPFGIDSLKDVQHKCSHCKKVLYRFDRMSGK
What are the official names of this protein?
Cell death-inducing p53-target protein 1 homolog, Protein LITAF homolog.
What is the protein family that this protein belongs to?
Belongs to the CDIP1/LITAF family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LFTR_SHEFN
Sequence: MNSLSYLNQSIGFPPPEQALTDPNGLLAIGGDLRPDRLAQAYYQGIFPWFNANDPILWWSPDPRAVFTPSHPFGSKSLIKFLKKSAWRFTINQAFLDVVAGCAGPRNTQDGTWISAEIQMAYYELHLQGHAHSIEVWDGEQLVGGLYGIPVGGIFCGESMFHRQTNASKAAFAILNQHLVKHDFQLIDAQVMNPHLVSLGAKALPRSEFLTILHQYRDRATSASMWNKQEVFIEF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADCK2_HUMAN
Sequence: MVAPWRVSVRVCLSHLRCFELRQGLSLLRPSECPRDARLCWLLLGTLPKVVSLCGDVGEGAPDVLSRRRVRCSGAAGAGPAESLPRAGPLGGVFLHLRLWLRAGALLVKFFPLLLLYPLTYLAPSVSTLWLHLLLKATETSGPTYIKLGQWASTRRDLFSEAFCAQFSKLHVRVTPHPWTHTERFLRQAFGDDWGSILSFENREPVGSGCVAQVYKAYANTAFLETDSVQRLGRASCLPPFSHTGAVGGLRELFGYLGNGRKPPENLADQSFLERLLLPKADLVGSNAGVSRAQVPGHQPEATNLISVAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVPVSSYQQAGIPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGANGLSSSQEAQLQQADICDTLVVAVPSSLCPLRLVLLDAGIVAELQAPDLRNFRAVFMAVVMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARKNTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAARPFLLTGPVCPP
What is the function of this protein?
The function of this protein is not yet clear.  It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
What are the official names of this protein?
Uncharacterized aarF domain-containing protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KI26A_HUMAN
Sequence: MVGRGVPLCAAQPAVAEGGPAREPPPLLEVSPRKRLPAGPDQDPCGSRPAPEGAGAGPEQGHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTTLRDPCLSALLLDKLPAPGALPACRPEAERRCDVCATHLQQLTREAMHLLQAPASHEDLDAPHGGPSLAPPSTTTSSRDTPGPAGPAGRQPGRAGPDRTKGLAWSPGPSVQVSVAPAGLGGALSTVTIQAQQCLEGMWSVSRVNSFLPPACLAEAAVAAVAVADTVRECPPVAGPDGLSKAWGRGGVCTSALVTPTPGSVGGSTGPSAAASFFIRAMQKLSLASKRKKPHPPPPPATRGTSTYPTDFSGVLQLWPPPAPPCLLRAASKTKDNPGSIGKVKVMLRIWPAQGAQRSAEAMSFLKVDPRKKQVILYDPAAGPPGSAGPRRAATAAVPKMFAFDAVFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAISWLFRLIEERRERTGTRFSVRVSAVEVCGRDQSLRDLLAEVAPGSLQDTQSPGVYLREDPVCGAQLQNQSELRAPTAEKAAFYLDAALAARSTSRAGCGEDARRSSHMLFTLHVYQYRMEKCGRGGMSGGRSRLHLIDLGSCEAAAGRAGEAAGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESLATAGCRTTMIAHVSDAPAQHAETLSTVQLAARIHRLRRKKAKYASSSSGGESSCEEGRARRPPHLRPFHPRTVALDPDRTPPCLPGDPDYSSSSEQSCDTVIYVGPGGAALSDRELTDNEGPPDFVPIIPALSRHRPSKGPRDADHFRCSTFAELQERLECMDGNEGPSGGPGGTDGAQASPARGGRKPSPPEAASPRKAVGTPMAASTPRGSSGPDTHQGTPEPCKAIVWGDQREDSSAWPELLVPEKAAVSGGRRPLPSPAPPPPQLLEACRAPEEPGGGGTDGVARTPPVGMSGQVAGSPMLPGATCPRLAAGSRCPERGLLTTTVTLQRPVELNGEDELVFTVVEELSLGALAGAGRPTSLASFDSDCSLRALASGSRPVSIISSINDEFDAYTSQAPEGGPLEGAAWAGSSHGSSISSWLSEVSVCTADSRDPTPQPRFSPDSLAGLDPGGPPALDGSLGDGSSGFLGPDRPDSPGPTWGPCPGEVAAVAPSRPGREPQAGPSRWASAAQTIHSSLPRKPRTASATTRVGCARLGQSPPGRGGLFEDPWLLRVGECDTQAASAGRAPSPTLGSPRLPEAQVMLACAQRVVDGCEVAARAARRPEAVARIPPLRRGATTLGVTTPAVSWGDAPTEVVACSGSLKASPTSKKGLAPKAGFLPRPSGAAPPAPPTRKSSLEQRSSPASAPPHAVNPARVGAAAVLRGEEEPRPSSRADHSVPRATSSLKARASKVEAAHRLAGHASLERYEGLAHSSSKGREAPGRPPRAVPKLGVPPSSPTHGPAPACRSGAAKAVGAPKPPVGGGKGRGLVAGGSRALGPSVKLSTASVTGRSPGGPVAGPRAAPRAGPSVGAKAGRGTVMGTKQALRAAHSRVHELSASGAPGRGGSSWGSADSDSGHDSGVNVGEERPPTGPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFHHSGGSSGYESLRRDSEATGSASSAPDSMSESGAASPGARTRSLKSPKKRATGLQRRRLIPAPLPDTTALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRPRPTPREAPTQGLACVSTRLRLAERRQQRLREVQAKHKHLCEELAETQGRLMLEPGRWLEQFEVDPELEPESAEYLAALERATAALEQCVNLCKAHVMMVTCFDISVAASAAIPGPQEVDV
What is the function of this protein?
Atypical kinesin that plays a key role in enteric neuron development.  Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling (By similarity).  Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity).  Plays a critical role in cerebral cortical development.  It probably acts as a microtubule stabilizer that regulates neurite growth and radial migration of cortical excitatory neurons (PubMed:36228617).
What are the official names of this protein?
Kinesin-like protein KIF26A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF26 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RT02_ACACA
Sequence: MFNRIHITVNQLVASDLFLGYHIANWNPRTNFFLIGKYKNTNIFNLNYTYFLAKKFIVFLSELFVNKGHLWLVNENFSLFNRSSELYQLYSLFPEITFLNSKWCKGMLSNYKYVSIVKPAKFPHSIFVPNIQNNHYVINESFIINIPSIAIVDSIDNPSNVFFPIPGNSKSLKSLFFFYMVIAKSLFYSRYITSSKFIFNSINRLNGLNSKLYRNLFVRDYFAFFKKRFLLENIIFLFKSGFFSKKKFNFLFRPKMHITSKTLLFKWKMPLLILSSVFKNVLHWDIFNKIVLKKRLVVKNLQFFKTLMFVLI
What are the official names of this protein?
Ribosomal protein S2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS13_CORA7
Sequence: MARLAGVDLPRNKRMEVALTYIYGIGPARAKELLEKTGISPDLRTDNLDDDQLSALRDVIEATWKVEGDLRRQVQADIRRKIEIGCYQGIRHRRGLPVRGQRTKTNARTRKGPKKTIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: FTSZ_ENTFA
Sequence: MEFSLDNNINNGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITANTDVQALKHSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQVISESLQGADMIFITAGMGGGTGTGAAPVVAKIAKELGALTVGVVTRPFSFEGPKRGRFAAEGIALLKENVDTLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTVMENQGTALMGIGVASGEERVIEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEAQDASDIVTNAASGDVNIILGTSINEDLGDEIRVTVIATGIDESKKDRKPHRQTRQAVQPMQQTTQSVEMDQPKSQEEASAFGDWDIRREQNTRPKVDESSLEQVDKKEFDTFHREEPNHNDDELSTPPFFRRKR
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: LSPA_BRUA2
Sequence: MKRHAVWSSLFVVILAVLIDQGIKYLVESRMFYGQQIDLLPFLALFRTHNEGIAFSMLAWLHDGGLIAITLAVIAFVLYLWWTNAPERVFARYGFALVIGGAIGNLIDRVMHGYVVDYVLFHLPTWSFAVFNLADAFITIGAGLIILEEFLGWRRERISH
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL15_MONAL
Sequence: MGAYRYMQELWRKKQSDVMRFLLRVRCWQYRQLSNLHRAPRPTRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPVPKGATYGKPVHHGVNQIKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKAVHKHREMRGLTSAGKKSRGLGKGHKFHLTIGGSRRAAWKRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPX7_BOVIN
Sequence: MVAARAAAWLLLAAAACAPREQDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYLTETSGKEPTWNFWKYLVAPDGKVIGAWDPTVSVEEIRPQITALVRKLILKKREDL
What are the official names of this protein?
Glutathione peroxidase 7, GPx-7, GSHPx-7.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCKA_SHEB2
Sequence: MADGLNRVHFNPSTAQLVEFALLRGEGELTANGALVAKTGARSGRSPGDRFIVREPSSEAEIEWGPVNQAFDPGAFEGLWARVEAYLADKELFVSDLEVGADTEHYQPVRVTTQYAWHQLFARNLFIIPEEFNRKDKPVWQIINAPDFVCDPARDGTNSDATVILNFAERKVLLAGLKYAGEMKKSMFSVQNFLLPAQGVLPMHCSANVGKDGDTTLFFGLSGTGKTTLSADPKRFLIGDDEHGWAPGGVFNIEGGCYAKCIDLSQKNEPVIWDAIRFGTVLENVVMDKHRVPNYKDSSLTENTRAAYPLEHIAQRKEDNCGAEPHAVVFLTCDVSGVLPPVSILTKEQAAYHFLSGYTAKVGSTEIGSTSAIQSTFSTCFGAPFFPRPAGVYAELLMKRIESFGSQVYLVNTGWTGGPHGVGKRFDIPTTRAIVDAIVSGELKDVETVHLDTLNLAVPVAVSGVDSNLLNPINTWGDKALYAEYAQKLAEAFTKNFAKYQVSDAIRNAGPKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_ALIF1
Sequence: MTYFEAFFLALLQGFTEFLPISSSAHLILPSAILGWSDQGLAFDVAVHVGTLAAVVIYFRKEVVTLLTAWVGSIVKKEHNKESNLAWLIVLATIPAALFGLLFKDFIEIYLRSAWVIAATTIVFGLLLWWVDKNATLAKDEYQMTWKKALFLGIAQAMAMIPGTSRSGITITAALYLGFTREAAARFSFLMSIPIITLAGSYLGLKLAMSDISIHLGLLSTGVIVSFISAYICIHFFLKLISSMGMMPFVIYRILLGSSLLVWLALH
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYH_RICTY
Sequence: MIDNLQPLRGMKDLLPDDYQVHNYIINKARDVGVLYGYKQMSTPILEYTRVFNRCMGDSSDVISKEIYSFVDKSNNAIALRPEFTSGIIRSFISNGLHHKLPLKLFSTGPVFRYDRPQAGRQRQFHQLNYEYLGAKGAITDAETLKLAVDILKALEIEEDTTLELNSLGCSESRIVYQQKLVEYLNDFKDKLSGESKIRLNKNPMRILDSKSEIDQKIIANAPILSDYHTNESKKYFDELLKYLDILGIKYSINPRLVRGLDYYCHTVFEFTTQKLGSQATILAGGRYDMLSRIMGNYDVHAIGFAAGIERIALMKKYNIFVIKPVFVLPIGKNNICYALDIVDKLRLHNIISIIDPIGKIAKRIQRVLNEDAKFIIFVGDEEKMNNNLKFKDLKNQKEYIIDLEKVLELLK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERB_STRT2
Sequence: MSEVKGLLVMDVDSTLVQEEVIDLLGEEAGVGREVAEITERAMRGELDFRQALNERVATLKGLPDSIFEKVYARIHFNKGAKELVDELHSRGFKVGLVSGGFHETVDRLAKEAGIDYVKANHLEVIDGFLTGKVYGEIVTKDVKVAKLKDWAAENGLKLSQTIAMGDGANDLPMIKTAGIGIAFCAKPIVRVQAPYQITEPDLYKVIEILDEVGK
What are the official names of this protein?
Phosphoserine phosphatase, PSP, PSPase, O-phosphoserine phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.