PharMolix/UniProtQA huggingface dataset:
Protein: VPS53_SCHPO
Sequence: MSNGNDNSLIIKNIGNNEFKFVETLHELLPEDITYDDLGSLRLSLSERLQESVKKLDANKKTYEDAKLSMGEKMDDLNSSIVSLLQELSTLQSVAENTQSSIVQMTSEIKNLDFAKQNLATSMTMLKRLQMLVTAYEKLRTLRQNQKFGEAISLMQATLQLLNFFKKYRSVERIASLSRSISEFQKSFYEQVFDTFQSQFKKESGMRGGFSPSSVQYLNELCRFIDIFAGDPPESVIRWYCRHQLEDFMKVFRENEEAGSLENLPRRYTWFKKLLQTYDQLHKPIFPPHWKVDFRLYEVFCEETKNDLSKLLKDDRLSLQVFVASLEQTLEFESFIDHRFYNTKSRFNSNFEPKERQAYNALSSVFEPHYTLYFNQQSQEFSILFENFALEKQTSTDESSQVLSSSIKLFQAYRKTLTQFVRLTRSSPLVGLKNLFIKWLRRYTQVELLDYQESSTFKDIAIRLNTAEYIYRTTIELEKRFQEISNKEFKDKMSFSEVLEVISSSRGTLLKFATGKFENVLNSDLEPLSKMDLKNIETVGDQSSYVGGAVQNMTAKASEFLSVVDLNMFARNFCDRSCESFTRQFLNAIYLAKPISEVGAEQLLLDLYSFKNALLKLPDLKQDYSITDSYINHLTIFMGYIETVLKTLLTPASPKAGFIQSYIFLVKDRSVTNFTVLLELKGVGKSDISSFLQQFSDFVKKTPQLEESSPIFKYLTINTAVEQAATRSRLSLDLAPESSRTLQNLGRLFTSKKKHV
What is the function of this protein?
Involved in retrograde transport from early and late endosomes to late Golgi, leading to the membrane fusion between late Golgi and endosomal vesicles.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 53, GARP complex subunit vps53.
What is the protein family that this protein belongs to?
Belongs to the VPS53 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: Y0004_DICDI
Sequence: MDFPSQSEKKKYITKKRTTLFSYDDDDDDDDFDQNREFIHMSSYEESKDQQNSFNTLLLSELSNCEDQKQQQQQQSSSPTQSDCDSSPTNNNNNNNTNNNIVHHLNNSNSIPISGSNNNNNNNNNNNNNNNNNNNNNNNSHHHHLRKGRRLFHDDNDDQPIYPASASLSSTKTNMFPSSPILYSSPSSQQQQQQQQQQSQSQQTNEFKVPSFTPLSFINNSSTNSMNIRPINNNRIYNNLNNNNNNNNNNNNNINNINNNNINNINNNYNNNNNNEEDQIFSSSLPTSPVSWSANGSMMNGHNINNITGNHSRFLSNGSYNKGNTFPSTEVKRVRPDQRAFNENSFSMSPTPSPPPTPSLKRNNYSSPKFEPVFIRLAEERTNRKRSTSMTSNVNNNNNNNANNNNVNNNNNNNNGPNSISSLIANVNPFTEEGRLQSLNKPCPSFQLVNNNNNNNNASNNNNDNNNNNNNNNNNNNNNDDTCNNNNNNSQNIDNNLITKFSLYKHTFQELDLIGEGSFGHVYKVRHRIDGCLYAIKKTKKPLKGQKDRDIVLREVYGLSAIKDHTNIVRYFNAWEEDSHIFIQMEHCNGGNIYKWVTEHIKQSESNLLLLAKQILTGIVYIHSLGLVHLDIKPENIYIIYKCNQNQIITNNNNTCSINNSSNGSDSYFKSKIKTTENDLDNFITTTNSVNNNNCNNNNNNNVDNQNNNNQNNYLIIDGNKINFNSITFKIGDLGLLNEATNTKIYSEGDSRYLSRELLHDDMSALKKSDIFSLGCTLYELARCKPLPKSGMEWDSIRNGILSFEKEDSIYDDNKNDFSTEFWQLIKSMIHPDPSVRPSAEQLLEHPLIKYGVIEIDDFENEIETLKNLLAEKEKVLIIQKEKQKLRQNQLQQKMQQPNFIELKQQPQQQQEKQQMLHQQKQQYLEQHNNNNDNNNNEFDESEKEYQIQLEQFKIQKMQFQLQQEQLQYQHQHKHQNFFTKQICTASQIEGGIKNMAL
What are the official names of this protein?
Probable protein kinase DDB_G0277539.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
Protein: PHOE_CITFR
Sequence: MKKSTLALVVMGITASASVQAAEVYNKNGNKLDLYGKVKAMHYMTDYDSKDGDQSYIRLGFKGETQINDELTGYGRWEAEFAGNKAESDSNQQKTRLAFAGSKLKNLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVVDGLDLTLQYQGKNQDRDVKKQNGDGFGTSVTYDFGGSDFAVSGAYTNSDRTNQQNLQTRGTGDKAEAWATGLKYDANDIYIATFYSETRNMTPISGGFANKTQNFEAVVQYQFDFGLRPSLGYVLSKGKDIEGVGNEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNKLGINNDDIVAVGMVYQF
What is the function of this protein?
Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes.
What are the official names of this protein?
Outer membrane porin PhoE, Outer membrane pore protein E.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: PEX2_MOUSE
Sequence: MAAREESTQSANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKAFLWLFLWRFTIYSKNATVGQSVLNIQHKNDSSPNPVYQPPSKNQKLLYAVCTIGGRWLEERCYDLFRNRHLASFGKAKQCMNFVVGLLKLGELMNFLIFLQKGKFATLTERLLGIHSVFCKPQNMREVGFEYMNRELLWHGFAEFLIFLLPLINIQKLKAKLSSWCTLCTGAAGHDSTLGSSGKECALCGEWPTMPHTIGCEHVFCYYCVKSSFLFDIYFTCPKCGTEVHSVQPLKAGIQMSEVNAL
What is the function of this protein?
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity).  PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase (By similarity).  PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-11', a modification that acts as a signal for PEX5 extraction into the cytosol (By similarity).  Required for pexophagy in response to starvation by mediating ubiquitination of peroxisomal proteins, such as PEX5 and ABCD3/PMP70 (By similarity).  Also involved in the response to reactive oxygen species (ROS) by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of PNPLA2/ATGL, thereby regulating lipolysis (PubMed:34903883).
What are the official names of this protein?
Peroxisome biogenesis factor 2, Peroxin-2, Peroxisomal membrane protein 3, Peroxisome assembly factor 1, PAF-1.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: PLSY_WOLTR
Sequence: MEKYIVFVLSYILGSIPFSLVITKIKGINLREVGSGNIGATNVARTGSKCIAALALLLDSLKGFIAVYIAKQFFDDGSFHMYASAILVVLGHMFPVWLKFSGGKGVATTLGILIALNISLVLAFVFVWLAVFFAFRYSSLASLTSTIAAVLSSFFFQRDLFFTLLTVAILIFFKHYRNIVNLLQGRERKFS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSRP_PROMT
Sequence: MSKKGKKQSKNNSSVDGNRRLAENRQARYEYEILETLETGLELLGTEVKSIRAGKVNLKDGFCLIKKDQIQLHNVHISPHNHAGKFFNHEPLRIKRLLAHRKEIEKLKISLERKGLTIIPLSLYLKGSWIKLKIGVGKGRKIHDKRDREKINDSKRDVANALKRF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MSY1_SCHPO
Sequence: MSSPTSPTSSPGRHHWSNSKDGMPPEYTNQDPNSDQADNENSDAKAHQPQHSPQHSTENQGHTGTSDTSSLEMELSKLHPESKQRQLPHSPEHERSRSPIASVVSYRSHMTLEDENQIFNAEMAVRGSQSLQRRPTGRSVRGSMRRLSSHRSKSMRTSKSKKSGDYERTAENEEAAQEAENHLDNFGVVTFGTEAPIKAPDHPVTIFGRIFKFIQQRSFYLRSLIYIIPLGVLLLIPVFIGRFYHPQPPYRDELGHEYERHLHVGGVDLMWMAIWWEIIWLSIWAARYAAKVIPYFFAFFVSFISNNVTKWRCMAVALEFPITLFLWMLAVYVSFLPIMTRRHIGDYGVPDHVRVKLPWQQSANNVLITLFITSIMNLVEKVLMQLIAMSLHRREYESRILYNKFAINELARLYGYARQRSFDFKDAIHRAQADVFKFADHQHGKKRAAAARVAQNALNKTTYKAISAFNFATDMVNKVAGEITNREVEKSSSPKSVVLHLLKTTRGCQSLARCLFEALVNPENPDLVLDDFIPVYTDETGEVDNATLEACYSIFDRDLNGDITCEEIELACVEIGKERKSISASLRDLNDSISKLDGICMFIVAVITLFIFLYLIARNFSGVLTSAGTTLLGLSWLFSGSAQELLSSIIFVFVKHPYDVGDRVDVMINGTVTSAMVKEISIMSTEFRLLTGKVIQAPNSLLNTLWILNMRRSDGIADPVTVNLKFGTTLQQIEQLRIKIIDFLKEEKRDYKPDLLTEVTDLPDLYSMSLCVVFFHKYNFQDEVLRMRRRNMFMCALMTYMQELDIVSPIFNSPGKSKDSPMYVNFNNGSMEGVKLSGGNDGGGTENHRDSTVGGGILKNPKAYPYREPTPPGSSDSDTASVSKKRVDFSLGTRHLMPAFDDVADIGSKRLGRDSLPDAVIENAGTEAMRREAEERRRAEEEEYERSQQESSSNEENENASRTSGARFSFSSKASRLSARPSARTVPPLQHISIQDLREPNENNTSKSARL
What is the function of this protein?
Regulates intracellular calcium levels and cell volume for survival in response to hypo-osmotic shock.  Acts as a mechanosensitive calcium channel in response to membrane stretch.  The conductance is about 0. 25 nanosiemens (PubMed:22910366).  Involved in maintaining vacuole integrity and protecting the nuclear envelope upon hypo-osmotic shock (PubMed:25041276).
What are the official names of this protein?
Mechanosensitive ion channel protein Msy1.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Perinuclear endoplasmic reticulum.
Protein: CIAO1_BOVIN
Sequence: MKDSLVLLSRILAHPDSRCWFLAWNPAGTLLASCGGDRSVRIWGREGDSWICKSVLCEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNEDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSEASWKCVCTLSGFHSRTIYDVAWCQLTGTLATACGDDAIRVFEEDPGSDPQQPTFSLTAHVPQAHSQDVNCVAWNPKERGLLASCSDDGELAFWKYQPSEGI
What is the function of this protein?
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity).  As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors.  The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins.  CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2 (By similarity).  Seems to specifically modulate the transactivation activity of WT1.  As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity).
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_CHLL3
Sequence: MELWLTGIVLKPRGLKGEVKVKPVTDYPEKFLSRKSYWVGGSPGDAVPLAVKHASLAGGFAWLFLEGVDSREKAEALAGRQLFIEASEAEPRKDDRAWLHELEGMKVLGAGRKEVGVLKEVLSMPAHEVYEIISGGRSVLVPAIEEFVEEISLEGRYIHVPRFDEFL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3925_PECAS
Sequence: MNLQHHFLIAMPALQDSVFKRSVVYICEHNEDGAMGLIINKPMDQFSVENVLEKLKIDPTPRDPAIRLDKPVFIGGPLADDRGFILHTPCSDFGSSISISEDTMITTSKDVLETLGTLKQPKNTLVALGYSAWENGQLEEELLENAWLTTPADKDILFHTPIAERWRAAARKLGIDIHNISTEAGHA
What are the official names of this protein?
UPF0301 protein ECA3925.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: GLPB_HUMAN
Sequence: MYGKIIFVLLLSEIVSISALSTTEVAMHTSTSSSVTKSYISSQTNGETGQLVHRFTVPAPVVIILIILCVMAGIIGTILLISYSIRRLIKA
What is the function of this protein?
This protein is a minor sialoglycoprotein in erythrocyte membranes.
What are the official names of this protein?
Glycophorin-B, PAS-3, SS-active sialoglycoprotein, Sialoglycoprotein delta.
What is the protein family that this protein belongs to?
Belongs to the glycophorin-A family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: DNAA_ECO8A
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PABP5_MACMU
Sequence: MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRVVGSKPLHVTLGQARRRC
What is the function of this protein?
Binds the poly(A) tail of mRNA.  May be involved in cytoplasmic regulatory processes of mRNA metabolism.  Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein 5, PABP-5, Poly(A)-binding protein 5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPAC2_YEAST
Sequence: MTEDIEQKKTATEVTPQEPKHIQEEEEQDVDMTGDEEQEEEPDREKIKLLTQATSEDGTSASFQIVEEDHTLGNALRYVIMKNPDVEFCGYSIPHPSENLLNIRIQTYGETTAVDALQKGLKDLMDLCDVVESKFTEKIKSM
What is the function of this protein?
DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.
What are the official names of this protein?
DNA-directed RNA polymerases I and III subunit RPAC2, RNA polymerases I and III subunit AC2, AC19, DNA-directed RNA polymerases I and III 16 kDa polypeptide, RPA19.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL33_TREDE
Sequence: MAKKTAVELIALQCSECKRRNYTTSKNRKNIQGKLELMKYCSFDRKHTLHKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NADK_RICCN
Sequence: MNINKIALIYNHNSKHLAIIEEIKKLYNYCKIEEAEVIIVIGGDGELLHNIHRYMHLNIPFYGVNLGSLGFLMNPLDTKKLLQNIHESTVSILNPLLMQVEDTSGQIYTALAINEVSIFRKTNQAAKFRIEVNGIERMSELVADGALVATPAGSSAYNLSASGPILPLESNMLCLTPICSFRPRRWHGALLLASATIKFEILNTNKRPVNATADFQEFNNITNVTVKSTKDKPVKLLFNKNHTLEDRIIKEQFGG
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIB_MYCPN
Sequence: MQMNHPIYIASDHTGLELKSLVIKHLEQQKLQVIDLGPTELDPLDDYPDYAFLLAQTMQANPNSLGILICGTGVGVCMAANKAKGILAALVVDSKTAALARQHDDANVLCLSSRFVVPEENIKIVDEFLQAQFEGGRHSKRVGKIIAYEREK
What is the function of this protein?
Catalyzes the interconversion of ribulose-5-P and ribose-5-P.
What are the official names of this protein?
Probable ribose-5-phosphate isomerase B, Phosphoriboisomerase B.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: UBIA_METCA
Sequence: MNVPHSVKSRADAYWRLMRFDKPIGIFLLLWPALWALWIAGEGRPDPGVAAVIVFGVVLMRAAGCVINDYADREFDPHVERTRLRPIAAGEVTSKEALILFMVLCLTAFALVLTMNWLTIALSVPGAFLAASYPFTKRYTHLPQAYLGLAFGWAIPMTFAAQTGSIPVVAWALYAATVLWALIYDTMYAMVDREDDVKIGIKSTAILFGKYDREIIGALQIAMLAILAGIGRYLGLGGLYALGLAAAAGFSVYQQVLIFRREKSKCFRAFLNNHWFGAAVFAGLFADYLWAG
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_STAHJ
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVVVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SYKM_YEAST
Sequence: MNVLLKRRSLTFAPRWLWCKCRSSRSRPYSLAHAVDTSKMEATRRNGQIVKDLGRYYPSMSESALHDLCQEYKEVTIADFNERFLGNPATLHHEDNPNLLLSINGRIKSIRFSGQKIVFIDLYNGSSGLKNDTQLQLIVNYNKIGGSSEDKANFSEYMNFLKKGDYIKALGYPGFSQSRVKMLSLICNKLPIVLSVSQLPLPSRLNDETKIKSNRVVDYQLNGTQTLLVRARIIKLLRKFLDDRNFVEVETPILSSKSNGAMAKPFITSSKDFDHLELRIAPELWLKRLIISGLQKVYEIGKVFRNEGIDSTHNAEFSTLEFYETYMSMDDIVTRTEDLFKFLITNLQKFFQDTRLPVPKTFSELHLALSENNWKFRKVEFLPTLNKELGIDLMNSGLDINKPSELLKALPKDIAKKYFPSADNTGQLSSLQILNKLSDVFLEQRHCQSTLPTVIYHQPAILSPLAKTDPQNKQVTKRFEVFIKGKEYINAYEEENCPQLQLQKFLQQKQINELTGNKTETLSPVIDYQYVETMKYGMPPVGGFGLGIDRLCMLFCDKKRIEEVLPFGCVDDVNRQ
What is the function of this protein?
Catalyzes the attachment of lysine to tRNA(Lys) in the mitochondrion.
What are the official names of this protein?
Lysine--tRNA ligase, mitochondrial, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: UREE_VIBPH
Sequence: MIRFTQVINSEGRDNFTDRENCLIVCLTMDERTKSRLKVCLNNGDEAGLFLPRGTVLKEGDLLQAETGEIALVEAAEEVVSTAFTDDLLLLAKACYHLGNRHVPLQVELGWCRYLHDHVLDDMVKGLGLGVRVERAKYQPEPGAYGGSISGASHGHHHH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_DEIDV
Sequence: MSKVRIYTLAKDLGVENARMLEILDGLGVAYKSVSSTIEEETVDLIKQILEEESAPQAQDSTPVAETPAAAQPAAPQAASSQPAAAQAAQAVAEPVAAPEPAVNEIPHRAPVVTIMGHVDHGKTSLLDYIRKTRVAAKEAGGITQHVGAFEAKTSKGKIVFIDTPGHEAFTTIRARGANVADIAIIVIAADDSLMPQTREAIAHAQAAKVPMIVAINKVDLPQADPERVKTDLTQLNLVPEEYGGDLIVVPVSAKTGEGVEDLLEYISLTAELEDLRADPKGPFSGVIIEGKVDRQAGVLATVMVQEGTLHVGDFLVVGENYGKIKAMTDSAGGRIKEAGPSTPVQVLGFSEVPASGEKVQSAKNEHAARDVIAARADVRRDQENARDRRKTQRTLEDIMGPIGEVRTVNLVLRADTQGSVEALQGILARKEGEDVKINVMLAGIGAPTEGDVLLASTAEATILCFSVTPSGSVTKMAENKGVDIKSYRIIYELIDEVDRLIKGNVEPVFEERYLGRAEVRMVIRHPKSGNIAGSYVTDGMFRRNAKAKVTRGKQTVYEGTIVGLKRFKDDVREVQTGYECGINLDWNDVMEGDIIEASEMVEVEQA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_SHIFL
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRTGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLCS_SACS2
Sequence: MKRKYPYSLAKGLTSTQIAVIVAVIVIVIIIGVVAGFVLTKGPSTTAVTTTVTSTFTTTTTIPSTTTSTPSNTVVFYTWWGGGDGGEALSQIIPAVKQYAGLQMQTYSIPGAGGTNAKYAILALIQAGKPPAAFQVHYGPEMISYVEAAPNGIHTFVNMTPYLIQWGLLNNAVYAVLQAGAYNGTLLSVPINVHRGAVLYVNTQLLREYNLPFPYNFSTLVYDTVQLANHGVSPWIIPGGDGGWDQFNVWEDIFLYLAGPQLYNELIYGTLNFSNPTVQKLINETNYWFLNFTSYNYPGWQSMSWEQAFALIAQGKVAFQANGNWVTNYASYINVTVYPPLPQYISNSSVSVVETPFPGTQHYYALVIDTIGIPVGPQEQQALQLAHFWSSYQGQEVWTKYKAVTYYKNGTDWYAQPAQWYDYQQLINTSEQNFVYQLSDGGVFDDVFAQIDSGLLTLQQVGKVGLSAWNSTLVSSMQQEQNEWLAAAKLGLGYLGFPGHPFAGYYPPWVTNPSAYGLTNNTQKTSNSVMLFLLPFLALPLAIASIDNKYYLLK
What is the function of this protein?
Part of the ABC transporter complex GlcSTUV involved in glucose uptake (Probable).  Binds glucose.  Can also bind galactose and mannose (PubMed:10400586, PubMed:11260467).
What are the official names of this protein?
Glucose-binding protein GlcS, GBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Extracellular side.
Protein: PUR7_NOVAD
Sequence: MSRRRQIYEGKAKILYEGPEPGTLIQYFKDDATAFNAQKRGTINGKGVINNRISEYVFTRLAHIGIPTHFIRRLNMREQLVRQAEIIPIEVVVRNIAAGSISKRLGIEEGEPLPHTLIEYYYKDDALGDPMIAEEHIACFGWASNEEMQDISSMAIRVNDFLCGMFAAINISLVDFKLEFGRIWDGDYSRVILADEISPDGCRLWDMTTGEKLDKDRFRRDLGGEEEAYQEVARRLGLLENDGGPSEVFDLGAHRKLRGKK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: CNCG_MOUSE
Sequence: MSDSPSLSPPAPSQGPTTPRKGPPKFKQRQTRQFKSKPPKKGVKGFGDDIPGMEGLGTDITVICPWEAFSHLELHELAQFGII
What is the function of this protein?
Participates in processes of transmission and amplification of the visual signal.  cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
What are the official names of this protein?
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma.
What is the protein family that this protein belongs to?
Belongs to the rod/cone cGMP-PDE gamma subunit family.