PharMolix/UniProtQA huggingface dataset:
Protein: Y1694_ANASK
Sequence: MGRIFETRKATMFARWNKMAKAFTRISKDIAIAVKGGGPNPDNNPALRRVLQNARHLNMPKDKVEAAIKRASGQDQQAYEVVVYEGYAPHGVAVMVETATDNVVRTVANVRMHFKNNGGNMGNTGSVAFQFRRMGVFRLAPEGIDQDALELDLIDHGLEEMGESTGEKGEKLLVIRCAFESFGQLQAALEERKLNVLSAESEYVAQTPVQLGEEQAREVLELVDALEQDEDVQHVFHNLA
What are the official names of this protein?
Probable transcriptional regulatory protein AnaeK_1694.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPP1_HUMAN
Sequence: MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP
What is the function of this protein?
Lysosomal serine protease with tripeptidyl-peptidase I activity (PubMed:11054422, PubMed:19038966, PubMed:19038967).  May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases (PubMed:11054422, PubMed:19038966, PubMed:19038967).  Requires substrates with an unsubstituted N-terminus (PubMed:19038966).
What are the official names of this protein?
Tripeptidyl-peptidase 1, TPP-1, Cell growth-inhibiting gene 1 protein, Lysosomal pepstatin-insensitive protease, LPIC, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, TPP-I.
What are the subcellular locations of this protein?
Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: PRMA_CAUSK
Sequence: MTDYTPQQIVARGARADAEAAADAIDNHPGLEGATYSILEEDEDKGLWRIDAFPTTDEEDAGLLEVLAGYPLKVVRETLADADWLAMALSGLPPVRAGRFFVYGMHDRGRLPASTVNLRIEAGAAFGTGHHGTTVGCLMAYDKLIKARKFKKVLDVGAGTGLLAIAAARTGSRIAVGTDIDRPSVRISKENAKVNRANAKFVHASGLGHRLVTDNAPYDLVFANILARPLISLAQDIKTALVPGGTVILSGLLRTQERMVKAAYVSRGFKVVNRIHRDAWAALVLQRP
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLI1_SCHMA
Sequence: MTGSDSSMCDLEVKSSLSLTSHLHEYQRNPLFHINTTTLTTTTTINNHINTTSTNNYQQQNDTMYDNNNNNVDNDMKVKSSMNDCINDNTINDTHSTTVIHAENENPRRPIPLTNTSNLEGSTSNVGGNSNFQTMSGNTIPFLPISATNDGRYEWPPSMRYSSANTDRFIQGINTNTDNRQEDFRNQLTSNNNNNYNFKSNNTADNEINQTNHHNLPQFANEKLLDSVRSKNFNNTNISNKVECSSPDANMVAAVAFNAVRRWFTNSSTLTNSDNTMKSVWNENMRTGNSGTNSIGFMNQSNILPYASLNSRLQHPLLPPPLVLNSTVGNATTQNSTHNNYGMFMHRGHHSSGYVPNHTAPMLRGGKKRSHSQSSVNELFDISSLTRSSQGSLNIMQSMRGSHSMGPSAEGSYGHLSAASLGASPGASCDIRRTLSSNGNSSHTAPPAPFSERSPFWSPNSPHSSGSGFDNYQTSSHKSLPLPSTLQTYQQHSGYTSTSGSSGNRSTGCLNRAPFGHLAVLSSSNSLNKQIQQQSDSNSVSNCSIDVPKKLTTNSSNMILPSCRTLGLPTNSVTVSSSEITKNCNNNVLQSAMAFAAVAVAAAAASSTTSSITERENSSLLNKHVLENTLHRECRDHGLHQHPSSECESCSSTLTMGNNNNKLNESINSVYNNLVPSCFMKPPSSATIKSLATTTDNNNSNTNILSNDLSTDNRNKSLNKLPCYNNDADANDTCMDATNNENIQQGVLRKIIPSTPSHFQFSSKTYNQLTQNNSSNKPITAVNNGNDVNNGGNMSSSFTNPLHWPFESIPTPDWSHTWFNNNNNNNTNSTIRFQLNPNETIRRNGRVKIEQIDLNSTVLSKSEMSELLINENSNNNHHHLFGKGNNLLCPTLTKDLLKQHCALNNSDINSITNSLLNQQSSQRKQIDGTLNQMRGIKNFGRTCRITPVLEAITPGITTSISETSAVASSSTTAATPTTTGLFKQKSIEHSHKWQNQNVFSSRRNSTRDPSNNNNSGVGRCSVDEPDVDDDEELDDDGRVPQEGDPDFVETTCRWGDCTLQFDDQDELVKHLSTEHIAGNKKSFVCLWRECVRGTRPFKAQYMLVVHMRRHTGEKPHKCIFEGCIKRYSRLENLKTHLRSHTGEKPYQCEIPGCNKAFSNASDRAKHQNRTHSNEKPYTCKVDGCSKRYTDPSSLRKHVKTVHGAESLMKTSLQKKNSFGVNMLMKVYANKKHKGESWSDRPCGGSGFGGGHLFGNSNNNNSYPSQDKRSNGSMPGIRGRFGPRGMNDNGNIFHRGTYTDREQRPSSSSNPRDSCLACLSNPVHTTTIHPVDINAESIITEYPNQDLSKLKRFSIEESGRNTSHNMNWYLPETDNQNVHSSVLMMASSPAVYNTRNDYFPSFKCEHSIYPNYFSFARNMIHTEDTNQNDNNNNNLVLSWTSPTTPSPCDNLYLDQKINPSITLQPLSTTSNPVQSLSPSIDNPINSTGTKQKNLFSPVNESVTMIRNENCDQSKPVCVYGTSDDLAKDFKKSLKTEENNLIWNWKYSQPSIDGMNKDHCNKKHSILRFDDQDMKKPLPGYLSTSLESRSNTQLALNPNDQTVNQLTRSINNEHFNEMSNMSTTTINETYRENNLQFNFPLKWKVEDPLAYSKNMDNNSQTKNNNELNEENSPQSNQNECISNVPLLNNHYLEDVTEQKSQLCVIECPNRLRSMQDICSSNDIWDSESAAASSGIGSGVTTTTASDNSNPTAQNHHHQKQQPKHSHQHQNRTKSINSDNNYSNQDNVSTMDNDETFFNNENIKSDLGSIDRSSLFGTPRTDSNSTGCSYERTFNPQINYKNDNLIHSSCTCIQKRQKRDNSQSTCSYHRHYHDQLVDGNISSQLDSEQLSATSSQVSSGLGSMTSSNAGSGCNCTGTGLNNTNINVLDNVSGNVSSNICVNTLPRLVEGDNSSNLTNDYPNNSQVFNEDDNNISKMWRKYYKSYGYCSPCNNQPETFYPEVFNSETECYSNTPATVINGLSSTASPVPPSISTYHYHHNPHLHHQHQQRQSQHNLDLVMSNSNHYNDEMHFSPHSYVHSSSSNSSPFNSNRPHSVETFSHNNLTNNSLFDHRRYTHTSLSTTNNNHVNEMNNSINQINPKHPYNICLSSINNNNNQCDTNSNMILKRHSITDDLCHVNGTWFTNEYNGNDNHHYWTHPYNVNQLSIGNQIPNWLNKSVLTSSSPSSSSRLTSTSLTEAIRTHNSSDSLCVTSRFNDSINYYQEYTNCCQPTINSFQINQSSLSSTMSTKTSAKLQSKLSWTTDDNYSEYLCSNHSQNSYIQSNRLVNNNNSSNNDNLIEMDRNNRTNIQRNCSSELNCYTNFQNNTTQLENMDHINTNPLLISLASSQPFLMSSFNTTSISTTSEQTPYSSYHLTPTSNTVHQISQRGIEQMNKMNNLHSNNQLSTIASVTASETTTSTSTVSSYQNLKEREVYNFPVPNPLHTYINPFHSSNSLYSSFLQSVFEEPTFTSSSSSSSPSPSLLLSSSSSTHLGHFNQLFVNADPISNNLVVCNMSTMDTDCAPFHSSN
What is the function of this protein?
Probable transcription factor which plays an essential role in males to trigger female sexual development by inducing NRPS expression in male (PubMed:35385687).  NRPS produces the pheromone beta-alanyl-tryptamine (BATT), which stimulates female sexual development (PubMed:35385687).
What are the official names of this protein?
Zinc finger protein GLI1.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
Protein: LEXA_STAEQ
Sequence: MRELTKRQSEIYDYIKKIVQTKGYPPSVREIGEAVGLASSSTVHGHLSRLEEKGYIRRDPTKPRAIEIVSEQLDEVNVEETIHVPVIGKVTAGVPITAVENIEEYFPLPEHLTSTHNSDIFILNVVGESMIEAGILDGDKVIVRSQTIAENGDIIVAMTEDEEATVKRFYKEKNRYRLQPENSTMEPIYLDNVIVVGKVIGLYREM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RNC_NITSB
Sequence: MKQLEEFEKKLGYSFEDKKLLKEALTHKSYKSPVNNERLEFLGDAVLDLVVGEYLFKKFPKANEGELSKLRASLVNEEGFAKLAQKLDIGKYIFISQAEENNQGRTKPSLLSNAFEAVMGAIYLEKGLEKVRELSLKLLEEAYPKIDLDSLFKDFKTALQEFTQAHYGITPTYKLLGSSGPDHKKEFEVAVLLHEETISTAKGRSKKAAQQEAAKEALKILKARNE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_CUPPJ
Sequence: MNIHEYQGKEILRKYNVPVPRGIPAFSVAEALKAAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIDDVKTYATNILGMQLVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQKIALMASSEGGMDIEEVAAHTPEKIHTLIIEPSTGLTDADADDIARKIGVPDASVAQARQALQGLYKAFYDTDASLAEINPLILTGEGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDANEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPNVEAILVNIFGGIMRCDVIAEGVISASKAVNLTVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMEEAAQKVVAAAAGKK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: KYNU_BACCN
Sequence: MDQNPFEASYEYAIQSDKQDELAAFQNEFYKKADTIYLDGNSLGLLSKRAEKSLLTMLNSWKEHGIDGWTEGEYPWFFLSEQLSEHIAPLIGALSEEIIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPNEHLVRVKSRDGRTLDEEDIIAAMTDDIALILLPAVLYRSGQILDMKRLTAEAHKRGIHIGFDLCHSIGAIPHQFQEWGVDFAVWCNYKYLNAGPGSVGGLYVNKKHFARLPGLSGWFSSRKDKQFDMEHTLTAAEHAGAYQIGTPHIFSIAPLIGSLEIFKEAGIDRLRQKSLHITRYMLHLIDYELTDKGFTIGNPLEDEKRGGHIYLEHPEAARICKALKANGVIPDFRAPNGIRLAPVALYNTYEEVWKSVRILKKIMTNEEYKQFENKRGVVA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: OBG_BORDL
Sequence: MHLFKDSLNLIVSSGNGGAGCVSFLREKFKAKGGPDGGDGGRGGDVIFKVKSNLKTLSLYRNGQKLSASNGKSGMGLKKSGAAGSDLIIFVPPNTSIYDADSNCMLFELKNFDDEVVVLKGGRGGLGNVNFKSSTKRTPRFAQPGESGLTLNLRLELSLIADIGLVGLPNAGKSSLISKITASRSRVANYPFTTKIPHFGVVRVSYNDLIIADLPGIIEGASKGIGLGFEFLRHISKTQILVFLIDVSSDDFMSAYDILINELRVYDIGLLKKKRIIVASKLDLEGATENFNQLKSILSEERVLGISIYDNIGINELVSEFFSLVKI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSFI_PENAE
Sequence: MAIPQSCTVLVAGGGPGGSYTAAALAREGVDVVLLEADCHPRYHIGESLLPSMRYLLRFIDLEDTFEQHGFQKKLGAFFKLNAKSAGYTDFIRANGPNGYSWNVVRSESDEILFRHATKSGAKTFENVSLKSVNFEPYENDKFTSQDKLTNPGRPVSAEWKTKDGCSGTISFDYLVDATGRVGILSTKYLKNRKFNESFRNIAMWGYFKGNIPPSPGTDRENQPISEGMRDGSGWVWMLPLHNGTVSIGAVVRKDIFQAKKKALPEGTTEAQTLASLVALCPTISSYLEPAELASGIRQAADYSYSANAYAGPNFRIVGDAGCFIDPFFSSGHHLALSSALAAATSINACIRGDCNEFDASRWFAKKVDEGYTLFLVVVMAALKQIRMQEQPILSDLDEEGFDRAFTILRPVIQGAADKETAPKAKGESITETIDLCLTALNDLHDTELQRKLTSIVEAKGTPEQEQLLGKLSPDETAALHRMRAMHSILPMGELEDFENSNIDGFKARLEKGSLGLRRERALCRDHAGDLQM
What is the function of this protein?
Flavin-dependent halogenase; part of the gene cluster that mediates the biosynthesis of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections (PubMed:20534346, PubMed:23978092).  The first step of the pathway is the formation of the heptaketide backbone by gsfA which is initiated by priming with acetyl-CoA, followed by sequential condensations of 6 malonyl-CoA units (PubMed:20534346, PubMed:23978092).  The resulting benzophenone can undergo a spontaneous dehydration to form norlichexanthone (PubMed:23978092).  However, the true precursor for the griseofulvin biosynthesis is not norlichexanthone, but the heptaketide benzophenone that is O-methylated at 3-OH by gsfB to produce griseophenone D which is further methylated at 9-OH by gsfC to yield griseophenone C (PubMed:23978092).  Griseophenone C is then substrate of halogenase gsfI which is responsible for the regio-specific chlorination at the C13 position to form griseophenone B (PubMed:23978092).  The cytochrome P450 gsfF catalyzes the coupling of orcinol and phloroglucinol rings in griseophenone B to form desmethyl-dehydrogriseofulvin A which is further methylated at 5-OH by gsfD to yield dehydrogriseofulvin (PubMed:23978092).  Finally, gsfE performs stereospecific reduction of enone 18 of dehydrogriseofulvin to afford the final product griseofulvin (PubMed:23978092).
What are the official names of this protein?
Flavin-dependent halogenase gsfI, Griseofulvin synthesis protein I.
What is the protein family that this protein belongs to?
Belongs to the flavin-dependent halogenase family.
Protein: FX1AA_DANRE
Sequence: MADAAQNQMVEIDPDFEPLSRPRSCTWPLPRPEFPNPAAADSNTSSPAPSVKQEPSSTADFINNLSLLEENEDYPDQKPLMLCSEFQCQENCIHQQQIPSQQQQVPVLSSPVAAAAAAAAAAQRKSSSSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKLALQGGPEGGADSPGSQYGKWPGSPNSHSNDDFEAWTAFRPRTSSNASTLSGRLSPFIDDELGDSDVHMVYPGPGSGTKMTSTLPSLSEMAGSLGHSGSENVMENLLDNLNLLSPKNPSTGGPGSGSNQSSPSSLMQASPGYSPYSSPGLSAVSQQTQQDFRKCLYGQAGMGSMSPMPMQPLPESKPSFGPGGGTMGQFNCTAGLLKELLTSDGEPGDLMPSVDTVVSQSAGGSGCMLPPYSSGRNELMGGGPTHSHTLSHPHNMHGQAPPTSVALNGRSLHPLTAIGHSSVGGRLGSGKSPMQMQYGGSGHLGGGLPPYCSMSSNGYGRGPGMMAHQQLQHLEKLPSDLDGMPIERFECDVESILHDTLMDGESLDFNFDPMNSQQGFVPHSVKTTTHSWVSG
What is the function of this protein?
Transcription factor that regulates metabolic homeostasis in response to oxidative stress (By similarity).  Binds to the consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3' (By similarity).  Main regulator of redox balance and osteoblast numbers and controls bone mass.  Orchestrates the endocrine function of the skeleton in regulating glucose metabolism (By similarity).  May be involved in regulating cellular homeostasis in the eye (PubMed:17993506).
What are the official names of this protein?
Forkhead box protein O1-A.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and nucleus.
Protein: RS11_PROM2
Sequence: MAATVKKTGSKKSKRNVPNGVVHIQSTFNNTIVSISDTSGHVISWSSAGASGFKGARKGTPFAAQTAAEAAARRALDQGMRQIEVLVRGPGAGRETAIRALQVAGLEITLIRDVTPLPHNGCRRPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: NU4M_CERCA
Sequence: MLKLILMMIFISPICFMQGLFWMVHNLLFVITFVLILMNFCLNYFVNISYFMGFDVLSYGLILLSFWICSLMIVASESVNKYNNYKNLFLFNVLMLLIFLVLTFSSMNLFMFYLFFESSLIPTLFLILGWGYQPERLQAGVYLLFYTLLVSLPLLVGIFYLYKNCNTMNFYLLSNYMFNCNLLYLAMILAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGLLAVFSFLQLIGLKYNYIWVSISLIGGVLISLVCLRQTDLKALIAYSSVAHMGIVLGGLMTLSYWGLSGSYTLMIGHGLCSSGLFCLANITYERLGSRSLLINKGLLNFMPSMTLWWFLLSVCNMAAPPSLNLLGEISLLNSIVSWSWLTMISLSFLSFFSAAYTLYLYAYSQHGKIFSGVYSFSGGNIREYFLLFLHWFPLNLLILKSEVCLFWI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RL34_CAMJE
Sequence: MKRTYQPHGTPRKRTHGFRVRMKTKNGRKVINARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ALF1_AERPE
Sequence: MISSQDVGKRVRLSRILPDGRSVIFAFDHGIEHGPGEIPEERLDPRLLIREVVEAGVDAIMTTPGIARLTWDIWANRVAMIIKVSGKTSIRPQDDQFLQSAISSVDEVVALGGDGVAATVYWGSQFEDKMLERWTRIRLRAEKLGLPALQLAYPRGPHIKNRYAVDIVAYGARAAMETGADLIKTYYTGSTESFRRVVSAAGGVPVLMSGGARTPSPQEFLHKVYSVMEAGGGGVVVGRNIFQAGDIRAMVKAIRAIVHEGFDPEKASKLLG
What are the official names of this protein?
Probable fructose-bisphosphate aldolase class 1, Probable fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_BURCM
Sequence: MFQGASALTLDAKGRMSVPSRYREALQGQAEGRVTVTKHPDGCLLLFPRPEWEVFRAKIAALPMDAHWWRRIFLGNAMDVDLDSAGRILVSPELRMAAGLEKEVMLLGMGSHFELWDSQTYIAKEQAAMAQGMPDALKNFTF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CLPS_ZYMMO
Sequence: MSGDKDFDKDSDVTVITRTTPQTKKPQPYKVLMLNDDYTPMEFVVLCLQRFFRMGIEDATKVMLQVHQRGVGICGVFTYEVAETKVNQVVDFARQHQHPLQCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: MCM6_MOUSE
Sequence: MDLAAAAEPGAGSQHPEVRDEVAEKCQKLFLDFLEEFQGSDGEIKYLQFAEELIRPERNTLVVSFADLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPFAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIKDVEQQFKYTQPNICRNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDRCDFTGALIVVPDVSKLSTPGARAETNSRVSGADGYETEGIRGLRALGVRDLSYRLVFLACHVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVDEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDMRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKRLRQRDGSGVTKSSWRITVRQLESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMETDEGQGGVNGHADSPAPVNRFNGSSEDASQETVSKPSLRLGFAEYCRISNLIVLHLRKMEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKTIIEKVVHRLTHYDHVLIELTQAGLKGSSEGSESYEEDPYLVVNPNYLLED
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
What are the official names of this protein?
DNA replication licensing factor MCM6, Mis5 homolog.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Binds to chromatin during G1 and detach from it during S phase.
Protein: MOAC_CROS8
Sequence: MSQLTHINAAGEAHMVDVSGKAETVREARAEAFVEMRPETLSMIVSGSHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEVQLFADEARSRVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFQVDAHD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: FLIL_TREPA
Sequence: MAEKDSIGDIADDFEEQLVAPAADRVGFLPGLLRWVAIAVGAVIFIVTVVTATALVLAKQGSSHTAYPVSQEFRESRELLQYYESVGLIRTNTADALPGTVVVSVALGYPLNDKTAQQELSARLVELKDFLRSYFQRKTLSELRPEHEQKVKIEIRNEINDNVLSRSKVKDIRFTQFDVLKP
What is the function of this protein?
Controls the rotational direction of flagella during chemotaxis.
What are the official names of this protein?
Flagellar protein FliL.
What is the protein family that this protein belongs to?
Belongs to the FliL family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HIS4_ECO24
Sequence: MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTPA_ASPNA
Sequence: MATSENDKRSKPSSLRSIIAGSTAGAVEIAITYPAEFAKTRSQLNRRLPDAKKLPWPPFGSQWYAGCTTLIIGNSLKAGIRFVAFDWLKSLLQDENGQISGPKTVIAGFGAGFTESLLAVTPFESIKTQLIDDRKSQNPRMRGFLHGSRVIFQERGVRGFFQGFVPTTARQAANSATRFSSYTMLKQMAQGYVAPGEKLGTASTFALGGIAGLITVYVTQPLDTVKTSRMQSLEASKNYKNSFVCAARIFKDEGIFTFWSGAVPRLARLIMSGGIVFTMYEKTMDALDGLDPERRYI
What is the function of this protein?
Mitochondrial transporter that mediates citrate export from mitochondria to cytoplasm (PubMed:36177470).  Both ctpA, ctpB, and ctpD play important roles in citric acid transport across the mitochondrial membrane and function in a redundant manner (PubMed:36177470).
What are the official names of this protein?
Mitochondrial citrate transporter A.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: MSHD_STRGG
Sequence: MTTDAPLPAPGREVHTLDALDSAQAESVLALLSEAARSDGRQAVSEQGRLRIRGGHRDGVRHFLLTVDGALAGYAQLEDTDPVEAPAAELVVHPDRRGHGHGRALGAALLAATGKRLRVWAHGGSSAARHLAQVLGLSLFRELRQLRRSLVPLDLAEPVLPEGVTVRTFEPGRDDAAWLAVNRAAFAHHPEQGSLTQQDLDDRKAEPWFDPKGFFLAERDGEIVGFHWTKVHAEERLGEVYVVGVLPEAQGGGLGKALTSIGLHHLAAEALPTAMLYVDADNTAAVTVYERMGFTTHEVDLMYRTES
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: FUCR_ECOLI
Sequence: MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQLKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSLVTA
What is the function of this protein?
Transcriptional activator of the fuc operon.
What are the official names of this protein?
L-fucose operon activator.
Protein: SECB_ENT38
Sequence: MSEQNNNEMSFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSVGGIEGNQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.