PharMolix/UniProtQA huggingface dataset:
Protein: RRF_CAMJE
Sequence: MLNEIFNKQKTQSEKSLEALKKDFTTLRTGKVNIHILDHITVDYYGTQTPLNQVATVLASDASTISITPWEKPLLKTIESAIAAANIGVNPNNDGESVKLFFPPMTREQREENVKQAKAMGEKAKVSIRNIRKDANDAVKKLEKDKAISEDEAKKAYDEVQKLTDTYTTKIDEGVKSKESELLKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX7_MOUSE
Sequence: MDMNSFSPMMPTSPLSMINQIKFEDGPDLKDLFITVDAPESHVTTIETFITYRIVTKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKVFLTAQAEELSSYKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIETFSQKINLIDKISQRIYKEERDYFDEMKEYGPIHILWSASEEELVDTLKGMAGCIEQCCKATEKRMAGLSEALLPVVHEYVLYSEMLVGVMKRRDQIQTELDSKVEALTYKKADIDLLTEEIGKLEDKVECANNALKADWERWKQNMKNDLRSAFTDTAEQNIRYYEQCLATWESFLTSQTDLPSEEDSEEKL
What is the function of this protein?
Involved in the regulation of endocytosis and in several stages of intracellular trafficking.  Together with SNX4, involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A.
What are the official names of this protein?
Sorting nexin-7.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS10_LEUCK
Sequence: MAQKKIRIRLKAYEHRILDQSAEKIVETAKRTGAEIAGPIPLPTERTLYTILRSPHKHKDSREQFEMRTHKRLIDIVNPTDKTVDALRKLELPSGVAIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RGS4_PONAB
Sequence: MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVIICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQASKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein.  Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 4, RGS4.
Protein: GRP1_CUCME
Sequence: YKRGGGGWGGGGGWKGGGGGGGGWKGGGGGGKGGGG
What is the function of this protein?
Possesses antifungal activity against a number of phytopathogenic fungi, including H. sativum and F. culmorum.
What are the official names of this protein?
Glycine-rich protein GWK.
Protein: PCNA1_SACS2
Sequence: MFKIVYPNAKDFFSFINSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIMRIPKDVLSEYSIDSPTSVKLDVSSVKKILSKASSKKATIELTETDSGLKIIIRDEKSGAKSTIYIKAEKGQVEQLTEPKVNLAVNFTTDESVLNVIAADVTLVGEEMRISTEEDKIKIEAGEEGKRYVAFLMKDKPLKELSIDTSASSSYSAEMFKDAVKGLRGFSAPTMVSFGENLPMKIDVEAVSGGHMIFWIAPRL
What is the function of this protein?
One of the sliding clamp subunits that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.  Heterotrimer stimulates the Holliday junction resolvase Hjc.  DNA polymerase I, DNA ligase and the flap endonuclease may be constitutively associated with the PCNA heterotrimer forming a scanning complex able to couple DNA synthesis and Okazaki fragment maturation.
What are the official names of this protein?
DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen homolog 1, PCNA1.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: PYRE_STRP4
Sequence: MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLAYPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMNLPFAYIRSKPKDHGAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKADKNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: HIS1_MOOTA
Sequence: MVTNLLTLALPKGKLGQDALQLLQAAGLPVEGVATEARQLTFTFPAPGIRYLICRPTDVPTYVEYGAADLGIVGKDTLAEAGADVFELVDLGFGYCRFVVAAPRERWEEAGRSLENLLAGSRRVATKFPRVAASFFQERGLPVEIIKLHGNIELAPRAGLADLIVDIVSTGRTLKENDLVEVAPIFSSTARLIANRVSYRINYRRLTSVVEALKRAAGQGGEKIATTN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_SHELP
Sequence: MMTKLDPYFGEYGGMFVPQILMPALKQLEAAFVDAQNDPSFQAEFTDLLKNYAGRPTALTLTRNLSPNPLVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVERQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSASYDKAHYLLGTAAGPHPFPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIDEPSVKLIGVEPAGLGIDTPKHGAPLKHGKTGIFFGMKAPLMQDKEGQIEESYSISAGLDFPSVGPQHAHLAATGRATYESATDDEALAAFQLLARSEGIIPALESAHALAYAIKLAEAATEETLLVVNLSGRGDKDIFTVADILEKQQANNEESGNE
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: TX101_RAT
Sequence: MGACRIQYILLVFLLIASHWTLVQNIYCEVSRTLSLEDNPSGTFNWTSKAEKCNPGEFCQETVLLIKAEGTKTAILASKSCVPQGAETMTFVQYTAPPGLVAISYSNYCNDSLCNNRNNLASILQAPEPTATSNMSGARHCPTCLALEPCSSAPSMPCANGTTQCYHGKIELSGGGMDSVVHVKGCTTAIGCRLMAKMESVGPMTVKETCSYQSFLHPRMAEIGASWMPTSLWVLELLLPALSLPLIYFP
What is the function of this protein?
Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity).  May play a role in signal transduction and promote protein tyrosine phosphorylation (PubMed:11809740).
What are the official names of this protein?
Testis-expressed protein 101, Lipid raft-associated glycoprotein TEC-21.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted. Cytoplasmic vesicle. Note=Located on plasma membrane of spermatocytes, round and elongated spermatids, and testicular spermatozoa.
Protein: FPG_PASMU
Sequence: MPELPEVETTKNGISPYLEGAIIEKIVVRQPKLRWMVSEELAQITQQKVIALSRRAKYLIIQLETGYMIGHLGMSGSLRVVEKGDLIDKHDHLDIVVNNGKVVRYNDPRRFGAWLWTEKLDEFPLFLKLGPEPLSEEFDSDYLWQKSRKKQTALKTFLMDNAVVVGVGNIYANETLFLCNLHPQKTAGSLTKAQCGQLVEQIKQVLSNAIQQGGTTLKDFLQPDGRPGYFVQELRVYGNKDKPCPTCGTKIESLVIGQRNSFYCPKCQKR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: NFSB_SALTY
Sequence: MDIVSVALQRYSTKAFDPSKKLTAEEADKIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYTFNERKMLDASHVVVFCAKTAMDDAWLERVVDQEDADGRFATPEAKAANDKGRRFFADMHRVSLKDDHQWMAKQVYLNVGNFLLGVAAMGLDAVPIEGFDAEVLDAEFGLKEKGYTSLVVVPVGHHSVEDFNAGLPKSRLPLETTLTEV
What is the function of this protein?
Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred.  Capable of reducing nitrofurazone (By similarity).
What are the official names of this protein?
Oxygen-insensitive NAD(P)H nitroreductase.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: SOP2_CAEEL
Sequence: MSSNLTSNEMSSTSAIVEPPEAVKGNERDKSTRRSTSQVVRPEKHEVENALEDQCSSSSLPKEAQYYAKLDKKLEGKDPRSQFYEAVRLSADIFAHKFEKAVCSRQTFEPTNSIIKVLNTAEEEMLHEKVVPLPVSSKLQYYLNRGRYDTIFDRDEQLQRTADPMADEPDHVEKRVTSILEQASREMEEGEVEPVFYDGSDEDQELPIDLGAMRNLQRTNKFAARSSRMAARRGGRPGYRGAFRGAARGAPSRRPAPAAEVAPETPVAAPMAPAAPAAPATPEAAPAAEVMDTSIATEMPQESAVDLSNVSAATEMDTSKEGEASRPTSEKKKKIRTTEMDRLMSMDLGPKDGGRVGELGHMWPESRRRPAAPLPETPAAQPRKSLPRRAAEKKKPEDSDAAEEQEVEMEVDNDASTSTPRNARGGRGGGNRRGSRRGQKRTSGGSGKLVEPKKEPVDEPAEKIPKRSEAAPEVPATATTKEAPPSTSSSPPDAPATPATPASSDSRDSPRKIRAMIFSLTGSPPESETPPVLQQEQVISTAAPTAGRHPNIIQQVPHINRIPPQPLRRLTAPQAPPASQPEEPPVQQTVPVVKVELASAPAPIVRDPQSTEPVPPAMPTLVENNHEATLILPPNKTSDYTRWNAQDLINWVRLLITNNVDSTIAIMVREEFDGETLACLVLDDDFRKEVPIPYGHYKKMKIYGTEVLNHYRTEKYQADLRKFHEELAAWKAQQR
What is the function of this protein?
Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  Also required to repress expression of other genes and for localization of sor-1.  Binds RNA.
What are the official names of this protein?
Polycomb protein sop-2, Suppressor of pal-1 protein 2.
What are the subcellular locations of this protein?
Nucleus. Note=Forms subnuclear bodies.
Protein: RS5_METAR
Sequence: MAAPYQREQAAWIPKTRLGKMVAEGKITTMEEAFETGLPIKEYQIVDALLPDLVDEVLDISMVQRMTDSGRRVKFRTTVVVGNGNGYVGLAQGKGVQVGPAIRKAIENAKLNIIKVARGCGSWECGCGLTHTVPSQVEGRAGSLKVVLMPAPRGLGLAAGGPAKKVLEMAGYKDVWSRTEGETRTTINFALATYKALESTTTVRTRQKEEAQ
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PYRH_CLOBH
Sequence: MNEPKYKRVMLKLSGEALSGEKGFGFDFDFTKEISEQIKKLVDMGIEVGAVVGGGNIWRGRSGSEMDRTTADYMGMLATCINALALQDSLEQLGVNTRVQTAIEMKEIAEPFIRRRAMRHLEKERVVIFASGTGNPYFSTDTAAALRAAEIEADVILLAKKVDGVYDKDPHKYDDAKKYNKLSYIEVLEQGLQVMDSTATSLCMDNDIPILVFGLDEPCNIIKAVTGEEIGTLVSNSK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA_PROMH
Sequence: MTTTLSNALLSDILQQIRPLIGQGKVADYIPALAQVPANQLAMAVYTVDGELYQAGMADKRFSIQSISKVLSLTLALTRYDESEIWQRVGKEPSGLPFNSLIQLEMEKGLPRNPFINAGAIVITDMLQSRLSAPKQRMLEVIRALTNTADICYNTVVAKSEMEHLSRNAAIAYLMKSFDNFDNDVITVLETYFHYCSIEMSCVELVRCFSYLANQGICVGSKNQIITPRQARQINALMLTCGMYDGAGEFAFRIGIPGKSGVGGGIIAVVPDAFTVAVWSPELDKSGNSLAGCAALELLANKVGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RND2_MOUSE
Sequence: MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGHRQLRRTDSRRGLQRSTQLSGRPDRGNEGEMHKDRAKSCNLM
What is the function of this protein?
May be specifically involved in neuronal and hepatic functions.  Is a C3 toxin-insensitive member of the Rho subfamily (By similarity).
What are the official names of this protein?
Rho-related GTP-binding protein RhoN, Rho family GTPase 2, Rho-related GTP-binding protein Rho7, Rnd2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Lipid-anchor; Cytoplasmic side. Note=Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome.
Protein: ARLY_NITOC
Sequence: MSHNNVTHGKPWSGRFHEPTDTFVEEFTASIGFDHRLYRQDIHGSIAHARMLAKVGVLSREECDAIIQGLETIAQDISRGQFSWSVALEDVHMNIEAALTERIGPVGKKLHTGRSRNDQIATDIRLYLRDAIDLITAQLQRLQEGLLAIAEREAATIMPGFTHLQTAQPVTFGHHLMAWFEMLLRDTGRLADCRHRVNVLPLGAAALAGTTFPIDRAYTAELLGFDGIAENSLDAVSDRDFAIEFTAAGALLMTHLSRFAEELVLWSSAQFDFITLPDRFCTGSSIMPQKKNPDVPELVRGKTGRVNGHLVSLLTLMKGQPLAYNKDNQEDKEPLFDTVDTLLGCLRAFADMIPAITTNPDKMREAATKGYATATDLADYLVRKGVSFRDAHEIVGKAVALAIEQSKDLAALKLATLQDFSPVIEEDVFDVLTLEGSVAARNHLGGTAPAQVRAAIQRGREKLNSLA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_NOCFA
Sequence: MLISQRPTLTEEVIAENRSKFTIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTDIILNLKGLVVSSEEDEPVTMYVRKQGPGTVTAGDIVPPAGVVVHNPDMHIATLNDKGKLEIELVVERGRGYVPAVQNKASGAEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDRLILDVETKNSISARDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFGLPIEDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKVKLHALGLSLKDSPASFDPSSVVGYDASTGTWSDSGTFSDNDGGEQDYAETEQL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TRMB_BURPS
Sequence: MIHDDDPNAPGAPHDDDATAAPASATRAAPAAGDDDDANPLHLRRIRSFVTRAGRVSTGQRRAIDELGPRFVIPYGSAQPDWDAIFGRRAPRVLEIGFGMGASTAEIAALRPGDDFIGVEVHEPGVGALLKLIGEQQLSNIRIIQHDAVEVLAQMIAPDSLDGVHIFFPDPWHKARHHKRRLIQPPFVAQLAAHLKPGAYLHCATDWQNYAEQMLEVLSADPSLENTAQDYAPRPGYRPVTKFERRGLRLGHGVWDLVFRKKHAG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: NORW_SHIDS
Sequence: MSNGIVIIGSGFAARQLVKNIRKQDATIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLHLFPHTWVTDIDAEARVVKSQNNQWQYDKLVLATGASAFVPSVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKMVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILATLDRQRSIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLRWQINTESQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPV
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RORB_RAT
Sequence: MCENQLKTKADGTAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSSISNGLSNLNTETGGTYANGHVIDLPKSEGYYNIDSGQPSPDQSGLDMTGIKQIKQEPIYDLTSVHNLFTYSSFNNGQLAPGITMSEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLLEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPDIVNTLFPPLYKELFNPDCAAVCK
What is the function of this protein?
Critical for hindlimb motor control and for the differentiation of amacrine and horizontal cells in the retina.  Regulates the expression of PTF1A synergistically with FOXN4 (By similarity).
What are the official names of this protein?
Nuclear receptor ROR-beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, Retinoid-related orphan receptor-beta.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: SSB_BPNF
Sequence: MTNEIKATFDVTTLEGRMKILNAKNAGGASLKTCEDGAIIEAVGIAQYQQESDTYGDMKEETVTAIFTADGNVISAISKTVAEAASEIIDLVKEFNLDSFKVKVSKQKSSKGNEFFSLLLVG
What is the function of this protein?
Single-stranded DNA-binding protein required for the elongation during viral DNA replication by strand displacement.  Displaced viral DNA strands are transiently coated with the ssDNA-binding protein and therefore protected againt nucleases.  The latter is then probably removed by the replisome that performs lagging strand synthesis or during the events that lead up to the recombination process.  Has helix-destabilizing activity since it removes secondary structure from the ssDNA in replicative intermediates.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB, Gene product 5, gp5, Protein p5.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus single-strand-binding protein family.
Protein: COBQ_DEHM1
Sequence: MNAMAKLIMVQGTSSNVGKSILVTALCRIFKQDGYKVAPFKSQNMALNAFVTQEGGEIGRAQAVQAEACGIAPSVDMNPILMKPEADSKSQIVVNGKVDRTISAREYYEYAPLLLDTALAALNRLREQNDIVVIEGAGSPAEINLRQREIVNMRIAKTAGAPVLLAGDIDRGGVFASLIGTIDLLEPEERSYVKGYLINKFRGDASLLKPAIDVLEDRTSIPVLGIIPYLRNMAIAQEDSVYLDECKSGLGETDLDIAVIRLPRISNYDDFDALATDGASVRFVSKTGEIGNPDLIIIPGTKSTIPDMEYLWQNGLAETIIKKAGKGTHVLGVCGGYQILGKMIYDPHKTESETTELKGLGLLDTETTFEKEKSTTQVSGQVRFNNGLLADMAGCEVGGYEIHMGRTRLFTAQPAFQITKTPKGPADYLDGASNAEGTVLGTYIHGIFESDSFRRGFLNAIRRYKGIPERQAGYFDRDKEYDKLADIVRASIDMNKIYDILNEGIR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RL1_BACAH
Sequence: MAKRGKKYVEAAKLVDRAAAYSATEAVELVKKTNTAKFDATVEAAFRLGVDPKKADQQIRGAVVLPHGTGKVQRVLVFAKGEKAKEAEAAGADFVGDADYIGKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTFDVTKAVNEIKAGKVEYRVDKAGNIHVPIGKVSFEDAKLVENFRTIADTLQKVKPAAAKGTYMKNVTVASTMGPGVRVDVSTLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RL30_CLOBM
Sequence: MAKVKITLVKSLIGRKKDQIATVNALGLKKIGNIVEHEETPQISGMIKKVSYLLKVEEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: EFP_TERTT
Sequence: MATYSTNEFKSGLKVMLDGDPCSIVENEFVKPGKGQAFNRVKMKNLKSGRVWERTFKSGESLEGADVVDRDMQYLYNDGEFWHFMEPESFEQFQGDASVVGDSAKWLNEQDTVVVTLYNGSPLAVTPPNHVELEIVETDPGLKGDTAQGGTKPATLSTGAVVKVPLFLSTGETVRVDTRTGEYLGRANK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_SHIFL
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity through direct physical interaction.  Can inhibit both RecA recombinase and coprotease activities.  May have a regulatory role during the SOS response.  Inhibits DNA strand exchange in vitro (By similarity).
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAT_MACCJ
Sequence: MTKSQDIIEITNHYGAPNYHPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKEQADRVTLTSRAFHSDQLGPWYEKICKLAGKEMVLPMNTGAEAVETAIKAARRWAYDVKGVAKDQAEIIAMKGNFHGRTLAAVSLSSEAEYQRGYGPLLGGFKLVEFGDIEQIKSAITPNTAAVLLEPIQGEAGINIPEDGFLKQVRDVCTENNVLFIADEIQAGLGRSGKMFATDWDNVVPDMYILGKALGGGVFPISCVLADKEILEVFNAGSHGSTFGGNPLACAVSNAALDVLVDEKLAERSLELGEYFQSKLKEIDNPVIKEVRGKGLFIGVELNEAARPYCEQLKELGLLCKETHDTVIRFAPPLIISQEDLDWAIDKVKQVFSK
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR2_SALTY
Sequence: MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPAVVFDDIVTNEQIQKRAEGISAYYDELIEMTSYWHLLGEGTHTVNGKTVVVNLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGVDDPEMAEIAEECKQECYDLFVQAAQQEKEWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.  R2 contains the tyrosyl radical required for catalysis.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase 1 subunit beta, Protein B2, Protein R2, Ribonucleotide reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: FXL15_DICLA
Sequence: MDEEAKIRTCQLLDLPWEDVLIPHILCYLPLQHLVSLQRVSKQFHSLIQVYLTNCRTFDLTSIGPSIPKEAFCSMLKDNKVLHSLSLQNCSDWVTDKELLPVIGQNQHLQRVDMSGCVCLTRHSLVAVSLSCMHLQHLGLAHCEWVDSLSLRSLADHCGGLQSIDLTACRQLKDDAICYLAKKCLKLRSLSLAVNANITDESVEEVAKNCRGLEQLDLTGCLRVRNQSIRTLAEYCPKLQSLKVNHCHNVTESSLDPLRKRNVVIDVEPPLQRALVLLQDVLGFAPFINLQI
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Acts as a positive regulator of the BMP signaling pathway.  Required for dorsal/ventral pattern formation (By similarity).
What are the official names of this protein?
F-box/LRR-repeat protein 15.
What is the protein family that this protein belongs to?
Belongs to the FBXL15 family.
What are the subcellular locations of this protein?
Cytoplasm.