PharMolix/UniProtQA huggingface dataset:
Protein: DAPA_SYMTH
Sequence: MPTFGRLLTAMVTPMTPDGAVDYQRAGELAKHLVAAGSEGLVVSGTTGESPTLSHEEKLRLFETVVDAVGGQVSVIAGTGSNNTAESIRFSREAARTGVHGLLLVTPYYNKPPQEGLYRHFRAVAEAVDLPCILYNVPSRTSVNMLPATTLRLARDVPNIVGIKECADVGQLADILSGAPEGFRVWSGDDANLLPYLTVGAYGIISVASHVVGPQMRELIDAFLAGDTARAAAWHRRLLPVFRGLFAVTNPILVKAALRLTGFPVGPVRLPLVDATEEQEEALREVLAEAGVL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_SALAR
Sequence: MHEAQIRVAIVGAGGRMGRQLIQAALHMEGIQPGAALEREGSSLLGSDAGELAGVGKMGVIVQSDLALVKDDFDVLVDFTRPEGTLAHLAFCRKHGKSMVIGTTGFDEAGKQAIRDAAQEIAIVFAANFSVGVNVMLKLLEKTAKVMGDYSDIEIIEAHHRHKVDAPSGTALAMGETIAHALNKDLQDCAVYSREGHTGERVPGTIGFATVRAGDIIGEHTAMFADIGERVEITHKASSRMTFANGALRSALWLKTKKNGLFDMRDVLGLDVL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_MYXVU
Sequence: MAMYGGQIHLIIGPMFAGKSTELIRLVKRYQIARYKCLVVNYEKDARYGNGVRTHDNTCISAVPTASLDDVESISEHVEVIGIDEGQFFPNIVSFCERMANAGKVLIVAALDGTFQRKPFTNICELIPLAENVTKLNAVCMYCYKDASFSKRLGNETEIEIIGGSDKYKSVCRKCYFF
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
Protein: VNNL3_DROME
Sequence: MAVFLRRFLWLISFTLVLTDDNSVENKFYIAGVVEYRPTFMGGTSEQLLQANLAGYLEIMASGNGTTDIIVFPEATLNSVITLTAVPKFTEQSLCEEQGDDDPEIAPFLRSLACAAREYGTYLVVNVKERVSEQCTSDETCSSRGYSIHNTNVVFDRQGAVISRYRKWNLYLEPSTNRTESPEIATFTTDFNVTFGHFICFDMLFYTPAQDLVEQLGIRHVIVTKMFNSELPFLTASQFQQGWAWANRVNLLASGGSLPQGGISGSGIYAGQQGALARLMITDELVGQRKLLLAKVPLDPEEPIATDEILEPEIMTPVKLKLLQQPELKNFTTWELPMVRGSSVDKRICQEDLCCEFRVTWTLEDTQPEYNYRLGVWVGQRRYEEEQYSAIRLCGLFACKGASVESCGLVSEEEVHLQDHRVVFTDLQILGEFVRRPRRLILPSTLSSSSFYALQPSQLAWSMEELANVTRIKMELRQPHSQLMTFAIYGNYFDEYANGGAGRLGTLLFLLITPLIMMHLFRE
What are the official names of this protein?
Vanin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: H13_WHEAT
Sequence: MVSEAITALKERTGSMLTQIKKLVAAGKLTK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1.3.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CCD39_BOVIN
Sequence: MSSEFLAELRWEDGFAIPVANEENKTLEEQLSKLQDERSSMQDQLRDYEDRINAMTSHFKNVKQEFLFTQSLCKARDHEIESEEHFKMIAERELGRVKDEIQRLENEITSIREKKNDKENSIFKTTQKLDGLKCQMNWDQQALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLERLTVECNQRRKVLDNEFAETLSVQLELDKAAQDFRKIHNERQKLILQWESTIEQMQKRDKDIDNCAVALARIKQEIREKENLVKEKIKFLENEIGNNTEYEKKISVADRKVLKCRTEYQRHEANRIQLKDELDSLKATVNRSSSDLEALRKNISKVKMDINEETARLGKIKNHNQIVRKKLKEITEKTMSVEEKATNLEDMLREEERGVKEVEVQLNIVKDVLFKKVQELQTETMKEKALVSEIEGTRSSLKHLNHQLHKLDFETLQQQEIMYAQDFYIQQVERRMSRLKGDINSEEKQALEAKTVELQKTLEEKKSALCLLETQIKKLHNDLYFTKKSNSKYRDEKQSLMTKINELTLFNDRSEKELTKAKALKQDLMIEDNLLKLEVKRTRELLHSKAEEVLSLEKRKQQLHTAMEERTEEIKVHKTMLASQIRYVDQERQNVSAEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQAYYVIKQALVNNQMEKTGRSYEEEYSFVPMRIYDLVNQVQEINAWCCMSVPRSFQKVTPSSAEYEVKIQLEEQKRAVDEKYRYKQRQIRELQEDIQSMENTLTVIEHLTNNVKEKVTEKQAYVLQLNRETEEQKPKLERVTKQCAKLTKEVRLLKDTKDETLEEQDIKLREVKQLHKIIDEMIVDITQENAEIGVILQTYFQQSGLELPTTSTKGSRHSSRSPSQTSLLSARSSKSTSTSASQTSIKVLELNFPASPLTGSTSRPTSASSASSTGKSRKTNK
What is the function of this protein?
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella.  Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella.  Not required for outer dynein arm complexes assembly.
What are the official names of this protein?
Coiled-coil domain-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the CCDC39 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Note=CCDC40 is required for localization to axonemes.
Protein: BFR_MYCTU
Sequence: MQGDPDVLRLLNEQLTSELTAINQYFLHSKMQDNWGFTELAAHTRAESFDEMRHAEEITDRILLLDGLPNYQRIGSLRIGQTLREQFEADLAIEYDVLNRLKPGIVMCREKQDTTSAVLLEKIVADEEEHIDYLETQLELMDKLGEELYSAQCVSRPPT
What is the function of this protein?
Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.
What are the official names of this protein?
Bacterioferritin BfrA, Bfr.
What is the protein family that this protein belongs to?
Belongs to the ferritin-like superfamily. Bacterioferritin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Unlike its homolog BfrB, is not found in encapsulin nanocompartments.
Protein: RL37_SULIK
Sequence: MKGTPSFGKMNKSHTHIRCRRCGRNAYNVSKHYCAACGFGKTKKIRRYSWQNKKVNGVRIR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: RUVC_RUEPO
Sequence: MRILGIDPGLRTLGWGVIEQRGSRLSHVANGLCHSDGDDLGERLLSLHNQIVEVIEEYRPDQAAIEQTFVNKDGAGTLKLGQARGVALLTLAQAGLPVGEYAPNRVKKTVVGVGHAEKEQVIHMVKLQLPGCLPKGADAADALAIAICHAYYGSAQALSQREVRA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SMD1_SCHPO
Sequence: MKLVRFLMKLTNETVSIELKNGTIVHGTITSVDMQMNTHLKAVKMTVKGREPVPVETLSIRGNNIRYYILPDSLPLDTLLIDDSTKPKQKKKEVVRGRGRGRGRGTRGRGRGASRGF
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D1, Sm-D1, snRNP core protein D1.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to the nucleus predominantly.
Protein: TIG_KOCRD
Sequence: MKSAVEKLNPTEAKITIDIAYTDLKPFVQETYKELANQIQIPGFRKGKVPSKLIDQRVGFDFVVENALNEGLNAFYQQALTENELTPLSQPQVEVLSKPEENDREADTKVEISVAIRPEIELPDYKGLEIQVEAREATAEDEQKALDELRARFGTLKTVDRPAAEGDHVTLDLQALVDGEEVDAANDLSYEVGSGTMLEGIDEAVTGLSAGEDATFETTLAGGEHSGAEATVKVKVTAVKERELPEADDEFAQLASEFDTIAELKEDLKKQAAESAVVEQGIEARDKVLDKLVELIEVPVPEKVIEDQLAQHFDSEQAQASAEPGHDTEEHRAEVRQNAENAFRNEIILDAVAEAEEVGVEQSELIDYIINMSQQYGMDPNQFAQMLDGSGQAGMMVGEVRRRKALAKVLETATVTDSNGETVDLSSFVGTGDDAETDEVETEASATE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: LPXD_RICAH
Sequence: MVSSNFYKNLGPRKLMAIIDFLHDIIEPPKVHEDIVIHDIKILQEASSNDISFLSNHKYSEFLKTTKAAACIVPKNFTGEANPNTVLIRAENSYFAYGKLIDFFYAPIKSYHAKIMKSAIVADSATIGKNCYIGHNVVIEDDVIIGDDSIIESGSFIGRGVNIGKNARIEQHVSINYAIIGDDALILAGAKIGQEGFGFSTEKGVHHKIFHIGVVKIGNNVEIGSNTTIDRGSLQDTIIEDLCRIDNLVQIGHGVKIGKGSIIVAQAGIAGSSTIGKYCALGGQVGIAGHLNICDGVQVAAQGGVLQNIEACKIVGGSPAVPIMDWHRQSVIMKQLVKTSNSKLKK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: PSUG2_RHIL3
Sequence: MTLMKPRLSREMAEAIAAGSPVVALESTIITHGMPYPANLETALGVETVIRENGAIPATIAVVKGELRVGLEHDELEELAQSKGIVKASGRDLAVAMIRGQSAGTTVSATMLMADLAGIDVFATGGVGGVHRGAEQTFDISADLTELGRTKTAVVCAGVKSILDIAKTLEYLETQRVPVIAYGTEDFPAFFTRRSGFKADHRLDTPEEIAKAMWLHHQLGTGTGLLIANPIPEASALAPDFIDGTIADAVRDADERGIDRKELTPFLLARINELTKGESLKANIELVKNNARLAARIAVAYAPLKKARN
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase 2, PsiMP glycosidase 2.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: ANM7_DROYA
Sequence: MSCFSHVMNPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFAALKKTIAGMREAGREVHVLDIGTGTGILSMMAVEAGADSVTACEAFLPMANCAERILAANGAGDKVRLIRKRSTEIQVGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNSLKTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQFDFQRKLEREKQRAQLLTLQSKQPGAAELVFYWWDIQLDDGGEILLSCAPYWAHPQLKELAAEKGKDHPLANVLPWRDHWMQAIYYIPKPLQLVEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRSRIGQINQSTRNKRYLRYLEENIEAEKSNVLVLGNGCLLGLASSALGAASVLLHEPHRFSRRLLESIVTHNQLKNVQFLDKVEELEDSQLSALTHVFAEPYFLNAILPWDNFYFGTLLTKIKDRLPESVKISPCSARIYALPVEFLDLHKIRAPVGSCEGFDLRLFDEMVERSAEQAVSLVEAQPLWEYPCRALSEPQEVLNVEFSSFTQEHSLKGSIELKHPGTCNGVALWVDWQLVEENSPRSIVSSGPSEPVVPGEFVKWDMFVRQGVHFPRRPTGGITHLEWSTDFKPVLGELNFSFGQKKL
What is the function of this protein?
Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).  Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3 (By similarity).
What are the official names of this protein?
Protein arginine N-methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
Protein: METJ_SODGM
Sequence: MAEWKGEYVSPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDHDLRKERNDEIPEVAKDMMREMGIDPDTWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANIA_NEIMA
Sequence: MKRQALAAIIASMFALAACGGEPAAQTPAASAEAASSAAQTAAETPAGELPVIDAVTTHAPEVPPAIDRDYPAKVRVKMETVEKTMKMDDGVEYRYWTFDGDVPGRMIRVREGDTVEVEFSNNPSSTVPHNVDFHAATGQGGGAAATFTAPGRTSTFSFKALQPGLYIYHCAVAPVGMHIANGMYGLILVEPKEGLPKVDKEFYIVQGDFYTKGKKGAQGLQPFDMDKAIAEQPEYVVFNGHVGAIAGDNALKAKAGETVRMYVGNGGPNLVSSFHVIGEIFDKVYVEGGKLINENVQSTIVPAGGSAIVEFKVDIPGSYTLVDHSIFRAFNKGALGQLKVEGAENPEIMTQKLSDTAYAGNGAAPAASAPAASAPAASAPAKSDY
What is the function of this protein?
Catalyzes the reduction of nitrite to nitric oxide (NO).  It could be essential for growth and survival in oxygen-depleted environments (By similarity).
What are the official names of this protein?
Copper-containing nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RS19_BACAC
Sequence: MARSLKKGPFVDDHLMSKIAKLNETEQKQVVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTYKGHDADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RS7_STRZT
Sequence: MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVYGAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SYP_MACCJ
Sequence: MKQSKMFIPTLREVPSDADSKSHQLLLKAGMIKQVASGVYSYLPIAKRVLNKIESIVREEMEAIDGVEILMPALQPSELWSESGRWQSYGAELMRMTDRHGREFALGPTHEEIITSLVRDELKSYKKLPVTLFQIQNKFRDEKRPRFGLLRGREFIMKDAYSFHATEASLDETYQDMYNAYSKIFSRLNLQFRPVIADSGAIGGSHTHEFMALAEIGEDTICYTDGSDYAANIEKAEVVYHPNKKHTEENVLEKVHTPGVKTAQQLADFLKRDLDEIVKSMIVKVDDQFVMFLIRGHHELNDIKVKSFFGTEHVEMATDDDIRSILDASPGSLGPVGVNKIDIYADNSVQDLNNLAVGANEDDYHYVNANVDRDFNVKAYGDFRFILEGEPAADGSGPVKFAEGIEIGQVFKLGTKYSESMNATFLNDQGRAEPMIMGCYGIGVSRTLSAVIEQHNDDKGIIWPTAITPYEVHIISVNPKQEVQKNLADQLYDTYRTQYEVLYDDRAERAGVKFNDADLIGIPVRVVVGKQAADGIVEVKNRRTGDAVEVHIDNLQETIQSIYASFES
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTC_ACTSZ
Sequence: MKITLKKLLILAIVPFLYACSSDRANYDDVFAKDTHGLDLLTGQFSQNIDQIWGVNELLVASRKDYVKYNDSYYTRSHISFDEGMITIETLADVNRLHSAIVHTLLMGSDAKGIDLFASGDTPISSRPFLVGQVVNNFGQSITNVNVANNFATYLIQNKLQQRRLNNGRTVQFVSIQMIANHVNIRARKYLPFVRKASRQYGIDESLILGIMQTESSFNPYAISYANAIGLMQVVPHSAGRDIFKMKGRSGQPSKSYLFDPAKNVDAGTSYLWLLRNEYLAGIQNPTSMRYAMISAYNSGAGAVLRVFSDDPDEAIYIINRMQPEQVYRILTTGHPSAQARNYLVKVDKAQRSYRRVR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: WECF_SALPK
Sequence: MTVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLRFYGSKKALAQAVIAKAKANRRQRFFFHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSNGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGELLYFPTRMDPSLNAMAKERQRAGKLTILVGNSGDRSNQHIAALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQAGLALFSAENLQILSEKMEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQVVREAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MAIL1_ARATH
Sequence: MDIDVGPVDPSVLYEQDLHVSSAVWEGQERGLLRCQEHTSLLHQWKLTDEQINLVDKAGFGYFRKIGPMSLNNSLISALVERWRRETNTFHLPLGEMTITLDEVALVLGLEIDGDPIVGSKVGDEVAMDMCGRLLGKLPSAANKEVNCSRVKLNWLKRTFSECPEDASFDVVKCHTRAYLLYLIGSTIFATTDGDKVSVKYLPLFEDFDQAGRYAWGAAALACLYRALGNASLKSQSNICGCLTLLQCWSYFHLDIGRPEKSEACFPLALLWKGKGSRSKTDLSEYRRELDDLDPSKITWCPYERFENLIPPHIKAKLILGRSKTTLVCFEKIELHFPDRCLRQFGKRQPIPLKVKRRDRKNRRLDDLDTSMSLACEEWAERGDHIVDSPGGGNVVDDGAYMEWYARISITKLYREAFLESQVMNMIACMREFEEAASGIALERLSPAEREVMESVKDTFANSLTFGGWQEVAVNSGYGKRRRRNEHTPTPNNGGGNDISSLLLQKEDS
What is the function of this protein?
Acts as an important factor for cell fate determination and maintenance throughout plant development.  Required for the organization of the root apical meristem (RAM) and the shoot apical meristem (SAM).  Required to maintain genome stability and cell division activity in meristematic cells.
What are the official names of this protein?
Protein MAIN-LIKE 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CMOB_HELPY
Sequence: MLICNDKSNPKTLLEEIMALRPWRKGPFEISQIKIDSEWDSSIKWDLVKNATPLKDKVVADVGCNNGYYLFKMLEHGPKSLVGFDPGVLVKKQFEFLAPFFDKEKKIIYESLGVEDLHEKYPNAFDVIFCLGVLYHRKSPLEALKALYHALKIKGELVLDTLIIDSPLDIALCPKKTYAKMKNVYFIPSVSALKGWCERVGFENFEILSVLKTTPKEQRKTDFILGQSLEDFLDKTDPSKTLEGYDAPLRGYFKMLKPSKR
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: ISPE_CHESB
Sequence: MKLECIAPAKINLALHVIGRRTDGYHLLESLVAFAAFGDRLSVEKAEADTFLLAGPFRDGLEGSGNFVLNARDLLREKFASRASSPVAITLEKNLPVASGIGGGSSDAATGLKLLTRYWEIETEPAELAQIGLGLGADVPMCLFGQPLIASGIGEKLEPVSTLPSLPILLVNPGLPLATPAVFSSLVERENAPLPPAPRNKSAAELVNWLRLTRNDLEPAALSIMPVIGIVLRLLQTEGALIARMSGSGATCFGIFETASKARQAGEMISRRHPGWFVRATQTRASMPELSHV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: Y1486_MYCTO
Sequence: MWCPSVSLSIWANAWLAGKAAPDDVLDALSLWAPTQSVAAYDAVAAGHTGLPWPDVHDAGTVSLLQTLRAAVGRRRLRGTINVVLPVPGDVRGLAAGTQFEHDALAAGEAVIVANPEDPGSAVGLVPEFSYGDVDEAAQSEPLTPELCALSWMVYSLPGAPVLEHYELGDAEYALRSAVRSAAEALSTIGLGSSDVANPRGLVEQLLESSRQHRVPDHAPSRALRVLENAAHVDAIIAVSAGLSRLPIGTQSLSDAQRATDALRPLTAVVRSARMSAVTAILHSAWPD
What are the official names of this protein?
Uncharacterized protein MT1533.
What is the protein family that this protein belongs to?
To M.bovis Mb1522c, M.leprae ML1804 and M.avium MAV321.
Protein: FEN1_TALMQ
Sequence: MGIKHLYQVISENAPDAVKTGEIKNHFGRKVAIDASMSIYSFLIAVRSDGQQLMSEAGETTSHLMGMFYRTLRIVDNGIKPLYVFDGAPPKMKGGELAKRSARKREAHEAHEEAKETGTAEDMEKFSRRTVRVTREHNEECKKLLKLMGVPYIDAPTEAEAQCAVLARAGKVYAAASEDMDTLCFEAPILLRHLTFSEQRKEPILEIHLDKALEGLGMDMAQFIDLCILLGCDYLEPIPKVGPNTALKLIREHGSLEKVVEAIENDPKKKYVIPDDWPYQEARELFFNPDVRKADDPQCDFKWESPDVEGLVKFLVTDKGFSEDRVRNGAARLAKNLKTAQQSRLEGFFKPVAKTDAEKASMKRKHDEKIEEQKKRKKEDAKAKKEAKARPRGAV
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: SAHH_ARCFU
Sequence: MEGFRKIEWAERYMKVLGKIREQFRKERPLEGFTVGMALHVEAKTAVLVRTLVDAGAEVAITGCNPMSTQDDVADALRESGIACYAKRGMDVEEYYEALRNVIRAEPDIVIDDGADLIFLLHGEMESYAEKVKGASEETTTGVIRLRAMEREGVLKFPVIAVNDAYTKYLFDNRYGTGQSAIDGVIRATNLLMAGKIVVVAGYGWCGRGIAMRARGMGASVVVTEVDEIRALEAVMDGFRVMRMEDAAKIGDIFITATGNRDIIREEHIRLMKDGAILANAGHFNVEIDIPALERMAKAKREARKYVTEYDLGDKRVYLLAEGRLVNLVAADGHPVEVMDMSFANQALAAKYIAENWQKLERKVYRLPEELDRMVARMKLESMGVEIDQLTEEQVRYLSDWRCGT
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.