PharMolix/UniProtQA huggingface dataset:
Protein: MTNN_ECO57
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: OBG_DESAP
Sequence: MFKDYAKIHVKAGDGGNGCVAFRREKYVPYGGPSGGDGGRGGHVILRADGGLRTLVDFRYRTHYKAGRGTHGQGKNMHGRKGEDLVLRVPVGTEVRRAGDATLMADLTVDGQEYRVARGGRGGRGNARFAAANRRAPSFAEKGEPGEELWLELELKLLADVGLVGFPNAGKSTIISKVSAARPKIADYPFTTLEPHLGVVRVGEGESFVLADIPGLIEGAHRGAGLGHRFLRHVERTRVLIHVVDVSGREGRDPVADFEAINRELAAYDPRLAARPQLVAANKTDLPGARDNARRLAEAAGGRYEVFEISALTGEGLDRLIYRTYRLLETIPVEPAPAPIVPDERETDVTLFLVAREGNTYVVEGEGIERRVAMTDLDNPEAVQHLQELLVRIGVEDALRAEGIRPGDNVRIGRFEFEYSENPTG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNT_ECOK1
Sequence: MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFTLRLWRNKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYLPVIIAGSLPWLGLLPGALYAGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFAPLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADVIDRQERLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTNB_BACC4
Sequence: MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHVGVPVLETELRPSAETILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDSGAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: TPIS_VESOH
Sequence: MRQVIIAGNWKMNASKEATNILVMDILSGMVDVKSKVIICVPFPYMAQVEALVGCSQLNLGAQDLNINKSGAFTGEVSVDMIKDFGARYVIVGHSERRSLYFENNEIVAQKVQVALNNNLTPLLCIGELLEDRDSGKTQEVVSEQIQAVIDLVGIDAFKDIIVAYEPVWAIGTGITATPQQAQDTHAFIRSMLAKYDDNVSQITSILYGGSMNPRNAAELMNCKDIDGGLIGGASLKAQDFLQICKAS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C_CHAGL
Sequence: MEIQNNLYGIDLYTILPESILIFCLLTTLIIDLSLDSKNKSWIIYLNTIGLILSGLFLCLQWNGIIPVTPFPSFKGDSFSIAFRFCIIIASLLSLLLSIDYIKRAGVQLMEFVIFLLGATIGGMFLCGANDLITIFTSLECLGLSSYLLAGYSKQDIRSNEAAMKYLLVGGASSAILAYGFSWLYGLSGGKIILSEIVDGLIFADFVNPLIKWITLTCIIVGLGFKISAVPFHQWTPDVYEGSPTPVVAFLSVASKTAGLALTIRIIATIFPYLENEWQFLLQILACLTMIVGNLVAITQTSMKRMLAYSSISQAGYLMIGIISSTNDGYASSLVYMLIYIFMNLGAFGCVILFGLRTGTDQIRDFSGLYLKDPWLASCLTIFLLSLGGIPPFAGFFGKIYLFWSGWQAGLYILTFVGLLTSVISIYYYLRIIKIMFVREAKEFSSYVKNYVIPVNSLLPQSSVETAMIVCMIASSVMGIAINPIIQVAQKTILSTIPFI
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic, NAD(P)H dehydrogenase, subunit 2, NADH-plastoquinone oxidoreductase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MUTS_NITEU
Sequence: MNKAEQSSHTPMMQQYLRIKAQHTDKLLFYRMGDFYELFYEDAEKAAKLLDITLTQRGSSAGEPIKMAGVPFHAADQYLARLVRLGESIAICEQTGDPATSKGPVERQVIRILTPGTLTDAGLLEERSNSIVLALALHRGSIGLAWLNLAAGDMRVLETSSDNLTSELERLHPAEILLPESLDLPATLNNFAGPKRLPDWQFDYEHAMQQLTRQFGTRDLNAFGCEDLHAAIMAAGALFEYVRLTQQTATDGSSGQLPGHLHTLQVERQDAYLRMDAATRRNLEITLTLRGEDAPTLSSLLDTCSTGMGSRLLRHWLHHPLRNRITLQQRLDTVSDLIGAQPETLYAGIRQQFKHIADIERITSRIALRTARPRDLSGLRDSLMRLPGIIELIATSAAAAVHRFIPPMQPDPLLTQLLVRALQPVPGAVIREGGVIADGFDAELDELRGLQGNCDEFLLQLEARERERTGIPNLKVEYNRVHGFYIEVTRAQGEKIPPDYRRRQTLKNAERYIIPELQAFEHKTLSAREQALAREKMLYERLLEQLADFIIPLQEIARSVAELDVLCAFAERAALSGYTKPVFTDDPVLIIEAGRHPVVENQVEHYIANDVQLGAITRENRQMLVITGPNMGGKSTYMRQTALTVLLAHCGSFVPAQIARIGPIDQIFTRIGAADDLAGGRSTFMVEMTEAAGILRNATAQSLVLVDEIGRGTSTFDGLALAFAIARHLLTQNQSYTLFATHYFELTRLAEEFPQAVNIHVTAVEHKRRIVFLHRIEEGPASRSYGLHVAALAGVPDRVIRNAAKILARLEQETLSRSPQQTLFETVEENAKAVPASVHPVLDYLERIHPDELTPRGALEQLYLIKSMLNQTD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: C102_BACCR
Sequence: MEKKVSAIPQPKTYGPLGNLPLIDKDKPTLSFIKIAEEYGPIFQIQTLSDTIIVVSGHELVAEVCDETRFDKSIEGALAKVRAFAGDGLFTSETHEPNWKKAHNILMPTFSQRAMKDYHAMMVDIAVQLVQKWARLNPNENVDVPEDMTRLTLDTIGLCGFNYRFNSFYRETPHPFITSMTRALDEAMHQLQRLDIEDKLMWRTKRQFQHDIQSMFSLVDNIIAERKSSGDQEENDLLSRMLNVPDPETGEKLDDENIRFQIITFLIAGHETTSGLLSFAIYFLLKNPDKLKKAYEEVDRVLTDPTPTYQQVMKLKYMRMILNESLRLWPTAPAFSLYAKEDTVIGGKYPIKKGEDRISVLIPQLHRDKDAWGDNVEEFQPERFEELDKVPHHAYKPFGNGQRACIGMQFALHEATLVMGMLLQHFELIDYQNYQLDVKQTLTLKPGDFKIRILPRKQTISHPTVLAPTEDKLKNDEIKQHVQKTPSIIGADNLSLLVLYGSDTGVAEGIARELADTASLEGVQTEVVALNDRIGSLPKEGAVLIVTSSYNGKPPSNAGQFVQWLEELKPDELKGVQYAVFGCGDHNWASTYQRIPRYIDEQMAQKGATRFSKRGEADASGDFEEQLEQWKQNMWSDAMKAFGLELNKNMEKERSTLSLQFVSRLGGSPLARTYEAVYASILENRELQSSSSDRSTRHIEVSLPEGATYKEGDHLGVLPVNSEKNINRILKRFGLNGKDQVILSASGRSINHIPLDSPVSLLALLSYSVEVQEAATRAQIREMVTFTACPPHKKELEALLEEGVYHEQILKKRISMLDLLEKYEACEIRFERFLELLPALKPRYYSISSSPLVAHNRLSITVGVVNAPAWSGEGTYEGVASNYLAQRHNKDEIICFIRTPQSNFELPKDPETPIIMVGPGTGIAPFRGFLQARRVQKQKGMNLGQAHLYFGCRHPEKDYLYRTELENDERDGLISLHTAFSRLEGHPKTYVQHLIKQDRINLISLLDNGAHLYICGDGSKMAPDVEDTLCQAYQEIHEVSEQEARNWLDRVQDEGRYGKDVWAGI
What is the function of this protein?
Functions as a fatty acid monooxygenase.  Catalyzes hydroxylation of fatty acids at omega-1, omega-2 and omega-3 positions, yielding primarily omega-1 and omega-2 hydroxylated products.  Metabolizes unsaturated and saturated fatty acids as well as N-acylamino acids.  Has a preference for long-chain unsaturated fatty acids over saturated fatty acids.  Shows activity toward saturated fatty acids with a chain length of 9-18 carbons with preference for longer fatty acids.  Also displays a NADPH-dependent reductase activity in the C-terminal domain, which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain.
What are the official names of this protein?
Bifunctional cytochrome P450/NADPH--P450 reductase, Fatty acid monooxygenase, Flavocytochrome P450.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the cytochrome P450 family.
Protein: RL22_BORA1
Sequence: METTAIIRGVHISAQKTRLVADLIRGKSVAQALNILTFSPKKAAVILKKAVESAIANAEHNDGADIDELKVTTIFVDKAQSMKRFSARAKGRGNRIEKQTCHITVKVGA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RF1_HISS2
Sequence: MKASIISKLESLKERHEELEALLGESSVINDQDKFRAYSKEYAQLEDVVKCFARWNWLNNNIEETQLLLDDPDMKEMAELEIEESKAEIENAEQQLQILLLPKDPNDEYNAYLEIRAGTGGDEAGIFAGDLFRMYSRYAESKRWRVEVLNANESEQGGYKEIIVKVNGEGVYGQLKFESGGHRVQRVPKTESQGRIHTSACTVAVMPELPENEMPEINPSDLRIDTYRSSGAGGQHVNTTDSAVRITHIPTGIVVECQDERSQHKNKAKALSVLASRIAQAEQERQAQAQADTRRNLLGSGDRSDKIRTYNYPQGRVTDHRINLTVYRLDEVMNGKIDELIQPIITEYQADQLAMLSEQN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_SYNC1
Sequence: MTLQDEIKQLAKEARDASRTLAQVSTTVKNDLLKGMADALVAATTALMAENAKDLEAGREKGLSDAMLDRLRLDEARIQGMADGLREVAELPDPVGEVTGMWRRPNGIQVGRMRIPLGVIGIIYESRPNVTADAAGLCLKSGNAVVLRGGSEAIHSNRAIAGVLKGVLAALGLPAGALQLVGTTDRAAVTELLKQEDYIDLIIPRGGEGLIRFVSENSRIPVIKHYKGVCHSFVDADADFDMAEKICVNAKVQRPGVCNAMETLLIHKDAAEVFVPRIARVLGELGVELRGCAETCRLAPGTTPAVDSDWGAEYLDLILAVKVVDGLDAAIAHIQQYSSLHTEVIVTRNYPNSQRFLREINSSVVMVNASSRFSDGNQFGLGAEIGISTTKLHSFGPMGLEDLTTRKFIVFGEGQVRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGKZ_HUMAN
Sequence: MEPRDGSPEARSSDSESASASSSGSERDAGPEPDKAPRRLNKRRFPGLRLFGHRKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
What is the function of this protein?
Does not regulate RASGRP1 activity.
What are the official names of this protein?
Diacylglycerol kinase zeta, DAG kinase zeta, Diglyceride kinase zeta, DGK-zeta.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Cell membrane. Cell projection, lamellipodium.
Protein: IBPB_ENT38
Sequence: MRNHDLSPLLRQWIGFDKLANALQSTAEHQAFPPYNIEKSDDNHYRITLALAGFRQDDLDIQLEGTRLTVKGTPEKPETETKWLHQGLVIQPFSLSFTLADHMEVTGATFTNGLLHIDLTRNVPEALAPQRIAISDRPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_CAMHC
Sequence: MGEILSVKDIKFKKGEKVFIRCDFNVPMDEFLNITDDRRIRAAIPTIRYCLDEGCSVILASHLGRPKNGYEAKFSLEPVAKRLARRMNREIKFVNDVIGKEAVEAVKNLKENEVLLLDNLRFEKGETKNDPEFAQKLASYANYYINDAFGVCHRAHASVEAITKFYDNKHKAAGFLLIKEVNFAANLTKRPVRPFVAVAGGSKVSGKLQALKNLLPKVDKLIIGGGMAFTFLKAIGYEIGNSLLEEDLVEEALNILREGKRLGVKIYIPVDAIVAPAISQDSVMKNVTVQEIPAGWMGLDIGPATIALFREALSDAQTIWWNGPMGVFEIDKFARGSLRMSHAIAESNATTVVGGGDTADVVERAGNSDEMTFISTGGGASLELIEGKELPGVRVLTIKNDEMEC
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCIN_HUMAN
Sequence: MQACGGGAAGRRAFDSICPNRMLALPGRALLCKPGKPERKFAPPRKFFPGCTGGSPVSVYEDPPDAEPTALPALTTIDLQDLADCSSLLGSDAPPGGDLAASQNHSHQTEADFNLQDFRDTVDDLISDSSSMMSPTLASGDFPFSPCDISPFGPCLSPPLDPRALQSPPLRPPDVPPPEQYWKEVADQNQRALGDALVENNQLHVTLTQKQEEIASLKERNVQLKELASRTRHLASVLDKLMITQSRDCGAAAEPFLLKAKAKRSLEELVSAAGQDCAEVDAILREISERCDEALQSRDPKRPRLLPEPANTDTRPGNLHGAFRGLRTDCSRSALNLSHSELEEGGSFSTRIRSHSTIRTLAFPQGNAFTIRTANGGYKFRWVPS
What is the function of this protein?
Transcription regulator specifically required for multiciliate cell differentiation (PubMed:25048963).  Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis.  Required for the deuterosome-mediated acentriolar pathway (PubMed:25048963).  Plays a role in mitotic cell cycle progression by promoting cell cycle exit.  Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211).
What are the official names of this protein?
Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas.
What is the protein family that this protein belongs to?
Belongs to the geminin family.
What are the subcellular locations of this protein?
Nucleus. Note=Excluded from the nucleolus.
Protein: RL7_MYCPN
Sequence: MAKLDKNQLIESLKEMTIMEIDEIIKAVEEAFGVSATPVVAAGAVGGTQEAASEVTVKVTGYTDNAKLAVLKLYREIAGVGLMEAKTAVEKLPCVVKQDIKPEEAEELKKRFVEVGATVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: EFP_SALAI
Sequence: MATTNDLKNGMVLNLDGELWAVVEFQHVKPGKGGAFVRTTLKNVLSGKVVDKTFNAGTKVDTATVDKRTMQYLYADGEDYVFMDLETFDQITVLGDTVGEAANYLLPEAEAVVATHESVPLYVELPTSVVLEVTYTEPGLQGDRSTGGSKPATVETGATVQVPLFITTGEKIKVDTRDGRYLGRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACINU_HUMAN
Sequence: MWRRKHPRTSGGTRGVLSGNRGVEYGSGRGHLGTFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPAVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEPPVPPQVSVEVALPPPAEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR
What is the function of this protein?
Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets; ACIN1 confers RNA-binding to the complex.  The ASAP complex can inhibit RNA processing during in vitro splicing reactions.  The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis.  Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function.  Induces apoptotic chromatin condensation after activation by CASP3.  Regulates cyclin A1, but not cyclin A2, expression in leukemia cells.
What are the official names of this protein?
Apoptotic chromatin condensation inducer in the nucleus, Acinus.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Nucleus, nucleoplasm. Note=Phosphorylation on Ser-1180 by SRPK2 redistributes it from the nuclear speckles to the nucleoplasm.
Protein: VCLC_PEA
Sequence: MAATTMKASFPLLMLMGISFLASVCVSSRSDPQNPFIFKSNKFQTLFENENGHIRLLQKFDQRSKIFENLQNYRLLEYKSKPHTIFLPQHTDADYILVVLSGKAILTVLKPDDRNSFNLERGDTIKLPAGTIAYLVNRDDNEELRVLDLAIPVNRPGQLQSFLLSGNQNQQNYLSGFSKNILEASFNTDYEEIEKVLLEEHEKETQHRRSLKDKRQQSQEENVIVKLSRGQIEELSKNAKSTSKKSVSSESEPFNLRSRGPIYSNEFGKFFEITPEKNPQLQDLDIFVNSVEIKEGSLLLPHYNSRAIVIVTVNEGKGDFELVGQRNENQQEQRKEDDEEEEQGEEEINKQVQNYKAKLSSGDVFVIPAGHPVAVKASSNLDLLGFGINAENNQRNFLAGDEDNVISQIQRPVKELAFPGSAQEVDRILENQKQSHFADAQPQQRERGSRETRDRLSSV
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
Vicilin.
What is the protein family that this protein belongs to?
Belongs to the 7S seed storage protein family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Vacuole. Note=Cotyledonary membrane-bound vacuolar protein bodies.
Protein: H2B7_ARATH
Sequence: MAPKAEKKPAEKKPVEEKSKAEKAPAEKKPKAGKKLPKEAGAGGDKKKKMKKKSVETYKIYIFKVLKQVHPDIGISSKAMGIMNSFINDIFEKLASESSKLARYNKKPTITSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.7, HTB11.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SPED_CLOPS
Sequence: MLGLKEKICLYGFNNLTKTLSFNIYDICYAKTEREKEDYIKYIDEQYNSERLTKILCDVTEMIGAHVLNISKQDYEPQGASVNVLITEEALPVALIDPSCNKGELSYLELRDSVVGHLDKSHLTVHTYPEFHPNNDIISFRVDIDVSTCGKISPLNALDYLIGSFDSDVITIDYRVRGFTRDVDGRKCYIDHDIKSIQDYIDEETLKKYDAMDVNVYQSNIFHTKMMLKDIGLNNYLFNSDPYELSPNDRREIRDRISKEMIEIYGGVNIY
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: NADD_GLUOX
Sequence: MRIGLLGGSFNPAHAGHLMLARRALRALRLDQVWLMVSPGNPLKPSKGMAPFRVRLASAERIADGRRIVATDIESRLGQRFTVKTVGLLKQRFPHVRFVWLMGADGLAQLSHWKRWRRLAAMVPIAVLPRPGSVSPALRGAAASVLRHQRRPSRESPVLAERKGNAWTFLSAPQNDISATALRESGQFRPDSDQE
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.