PharMolix/UniProtQA huggingface dataset:
Protein: GDF15_MOUSE
Sequence: MAPPALQAQPPGGSQLRFLLFLLLLLLLLSWPSQGDALAMPEQRPSGPESQLNADELRGRFQDLLSRLHANQSREDSNSEPSPDPAVRILSPEVRLGSHGQLLLRVNRASLSQGLPEAYRVHRALLLLTPTARPWDITRPLKRALSLRGPRAPALRLRLTPPPDLAMLPSGGTQLELRLRVAAGRGRRSAHAHPRDSCPLGPGRCCHLETVQATLEDLGWSDWVLSPRQLQLSMCVGECPHLYRSANTHAQIKARLHGLQPDKVPAPCCVPSSYTPVVLMHRTDSGVSLQTYDDLVARGCHCA
What is the function of this protein?
Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.  Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem.  It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which constitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886, PubMed:28846097, PubMed:28846099, PubMed:28572090, PubMed:23468844, PubMed:29046435).  On hepatocytes, inhibits growth hormone signaling (PubMed:28572090).
What are the official names of this protein?
Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSA_BRADU
Sequence: MSSSTSAAPVVTIGRVKFGNDLPISIIAGPCQLESRQHALEVASALKEIAARLNIGLVYKTSFDKANRTSASAARGLGLAQSLPIFAEIRSSLGLPVLTDVHEATQCAEVAQAVDILQIPAFLCRQTDLLLAAAATGKVVNVKKGQFLAPWDMANVVTKITSANNPNVLVTERGASFGYNTLVSDMRALPILARTTGAPVIFDATHSVQQPGGKGTSSGGEREFVPVLARAAVAVGVAGVFIETHPDPDSAPSDGPNMVPLREFEGLIRRLMAFDALAKNPR
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH_MYCTA
Sequence: MPSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVDWLLAQPDKPDLVFEATSAYVHRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAPNVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQTIGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLLNEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVGGAR
What is the function of this protein?
Involved in cholesterol degradation.  Catalyzes the conversion of propanal to propanoyl-CoA, using NAD(+) and coenzyme A.
What are the official names of this protein?
Propanal dehydrogenase (CoA-propanoylating), Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: NEF_HV2KR
Sequence: MGASGSKKCSRSLQGLRERLLRARGETCGGQWDGSAGEYLQFQEGSGRGQNLPSCEGQRYQQGDFMNTPWRTPAAGREGTLYKQQNMDDVDADNDNLIGVPVTPRVPLRAMTYKLAVDISHFLNEKGGLDGMYYSERRHRILDIYMEKEEGIIPDWQNYTHGPGVRYPKFFGWLWKLVPVDVPQGEEDHCLLHPAQTSGSDDPHGETLMWRFDPRLAYEYTAFNRYPEEFGYKSGLPEEEWKAKLKARGIPFS
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.
Protein: SYDND_NITMU
Sequence: MRTNYCGLIDVQYLDQTVILYGWVHRRRDHGGVIFVDLRDREGLVQVVCDPDNPTAFQVAEKIRNEFVVRITGRVRHRPPGTVNPNLISGEIEVLVSSIDILNASLTPPFLMDDESLSEATRLEHRYLDLRRPQMQENLRLRYKVAMAVRLFLDQHGFIDVETPMLTKSTPEGARDYLVPSRVNTGHFFALPQSPQLFKQLLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDIETSFLNESQIMQMMERMICTVFKSVRNIDLPTPFPRLTHGEAMSKYGSDKPDMRVSLVLTELTDVMQEVEFKVFREAALRTGGRVAALRVPGGGALSRKEIDDYTGFVAIYGAKGLAYIKVNALEKGMDGLQSPILKFLPENVIQIVLERTGAKDGDLIFFGADKAQVVNEALGALRAKVGHDRGLAESGWKPLWVVDFPMFERDEEENRWKALHHPFTSPAEGHEDLLETDPEKALSKAYDMVLNGSEIGGGSVRIHRQEVQSKVFRALNIGADEANEKFGFLLEALQYGAPPHGGIAFGLDRIVAMMAGAESIREVIAFPKTQRAQCLLTHAPSTVGEKQLRELHIKLRHA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INVA6_PAXIN
Sequence: MAPVAITPATLVGHDLKSSRASERATELSPVTLLDIFSRAVSLYPKHELSFVTSSAHDSSVQTRSFSEFDQYARALAWAMLAWGKPTGSVIVVYFTEHEDNMAAVWACLLAGHVPCLQPALSEQQAHKEGHVAHIKNLFSSATWLTNESGAEQVHSITGLDIRLLSELKARAETVGADFHAHQPNPDDEAILFLTSGSTGFSKVVVHTHRTILAACNAKGQSYGLTSESKTMNWVGFDHVAGSLEMHIAPLLYGASQLHVHVSAILADPSRFLRLIEEKSIQLAFAPNFLLAKLTRDLEKCSDLFGKFDLSSIKRINSGGEAVVSSTAQAFARTLKNFAKDGNASFVISAGFGTTETCAGCIYDPIDVLFTPPSYEFLELGTPLTGCEMCIVNPQDGVTPRPDGESGELQVRGPMVFVRYYNDPKATTSSFIEGVWYRTGDVGIIEKGKMRLNGRIKDTVIVHGVSYGIAELETYLQTVEGVTHSFLAAAPHRDPGQETEGFVIFYSPTFELDSEDAPAKLYATHRALRDVSVKMITLPPQQIIPIPLNQMEKTTLGKLSRVCLVNLFKQGELANHIARAEELLSIARGATFIAPSTETEKTLGRLYAEIFNLRVSDVSASDNFFELGGNSIDVIKLKREAESLFELPEILTVQILKHPVISSLAKYVDSLVSKDGSQEEYDPVVPLQLTSNKTPIFMVHPGIGEVLAYVDLAKYFQNERPFFALRVRGFEGQPLFTSMDEMASSYAAGAKRTQPHGPYAIAGYSYGGVVAFEVAKRLESMGDEVKFIGLVDIPPHIADRMHDWTSGMLNLSHLLGLMSKQDADNLAPSLRTLTRKEQFEVLWKLSPPERLTELQLTPEKHENWVYIAGGLSECGMTYQPGGSVSVLDVFYAMPPHDTKEDWLNQHLRRWADFCRSEPSFTNVPGHHDTLMDFDHVSGFQKIFRDALEARGL
What is the function of this protein?
Inactive atromentin synthetase homolog.  Does not accept 4-hydroxyphenylpyruvate (4-HPP) as substrate.  Both the adenylation (A) and the thioesterase (TE) domain of the invA6 enzyme are inactive.
What are the official names of this protein?
Inactive atromentin synthetase invA6, Nonribosomal peptide synthase-like enzyme invA6, NRPS-like.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: MTNA_YEAS2
Sequence: MSLEAIVFDRSELENVSVKVLDQLLLPYTTKYVPIHTIDDGYSVIKSMQVRGAPAIAIVGSLSVLTEVQLIKHNPTSDVATLYSLVNWESTKTVLNKRLDFLLSSRPTAVNLSNSLVEIKNILKSSSDLKAFDGSLYNYVCELIDEDLANNMKMGDNGAKYLIDVLQKDGFKDEFAVLTICNTGSLATSGYGTALGVIRSLWKDSLAKTDKADSGLDNEKCPRMGHVFPLETRPYNQGSRLTAYELVYDKIPSTLITDSSIAYRIRTSPIPIKAAFVGADRIVRNGDTANKIGTLQLAVICKQFGIKFFVVAPKTTIDNVTETGDDIIVEERNPEEFKVVTGTVINPENGSLILNESGEPITGKVGIAPLEINVWNPAFDITPHELIDGIITEEGVFTKNSSGEFQLESLF
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RBL_COUGU
Sequence: KASVGFKAGVKDYKLTYYTPEYKTLDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTTLDRYKGRCYHIEPVPGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEALYKAQAETGEIKGHYLNAPAGTSEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGXVVGKLEGEREITLGFVDLLRDDYIEKDRSRGIYFTQDXVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIRAASKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRPG_PORPU
Sequence: MILIIDNYDSFTYNLAQCVGELGHDVLVCRNDEIDVVKIKKLNPEKIIISPGPGKPTESGISLDVISSLAEYIPILGVCLGHQSIGYINGGSIIKVPKIMHGKTSQIYHDREDLFINLPNPFIATRYHSLIIDRANFPTNLAVTAWTDNNIIMACRHKHYKMLRGIQFHPESLWTVCGQQLLKNFLDSD
What are the official names of this protein?
Anthranilate synthase component 2, AS, Anthranilate synthase, glutamine amidotransferase component.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHCT1_BOVIN
Sequence: MEASDGQADEREEPLEQGTNARSLERRSSTTPAKDSLVRHAKGLDRDTFKICKEYLRPLKKFLRKLHLPKDLPQKKKLKYMKQSLVVLGDHINTFLQHYCRAWEIKHWKKMLWRFVSLFSELEAKQLRKLYKYTKNNQTTKFLMAFCPLDAPESSLLADQEDSLPKLCTAWGLRSHLNGMKERLSKLQAPGHPARLLKELRARGPRRRGSKLPQEPKLKRRRIKEAPDTPETCL
What is the function of this protein?
May play a role in regulation of apoptosis.
What are the official names of this protein?
CHD1 helical C-terminal domain containing protein 1, Uncharacterized protein C17orf64 homolog.
Protein: GSID_ECOLI
Sequence: MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAALFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVLGSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTVLLRHILPGTVSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPALAIFLTVLAFNLLGDGLRDALDPKIKG
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EAD_EBVA8
Sequence: METTQTLRFKTKALAVLSKCYDHAQTHLKGGVLQVNLLSVNYGGPRLAAVANAGTAGLISFEVSPDAVAEWQNHQSPEEAPAAVSFRNLAYGRTCVLGKELFGSAVEQASLQFYKRPQGGSRPEFVKLTMEYDDKVSKSHHTCALMPYMPPASDRLRNEQMIGQVLLMPKTASSLQKWARQQGSGGVKVTLNPDLYVTTYTSGEACLTLDYKPLSVGPYEAFTGPVAKAQDVGAVEAHVVCSVAADSLAAALSLCRIPAVSVPILRFYRSGIIAVVAGLLTSAGDLPLDLSVILFNHASEEAAASTASEPEDKSPRVQPLGTGLQQRPRHTVSPSPSPPPPPRTPTWESPARPETPSPAIPSHSSNTALERPLAVQLARKRTSSEARQKQKHPKKVKQAFNPLI
What is the function of this protein?
Acts as a DNA polymerase processivity factor; a transcriptional activator for several EBV promoters and inhibits the host DNA damage response (DDR) to double-stranded DNA breaks.  Plays an essential role in the viral lytic DNA replication by acting as a polymerase accessory subunit.  Stimulates the viral DNA polymerase activity and appears to function with it as a holoenzyme.  Increases the processivity of the viral polymerase, probably by acting as a sliding clamp that prevents dissociation of the polymerase from the active template.  In addition, BMRF1 transcriptionally activates the oriLyt early BHLF1 promoter.  Promotes G1/S cell cycle arrest through p53 induction.
What are the official names of this protein?
DNA polymerase processivity factor BMRF1, Early Antigen Diffused, EA-D, Polymerase accessory subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA polymerase accessory subunit family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Note=BMRF1 shows homogeneous, not dot-like, distribution in the replication compartments, which coincides with the newly synthesized viral DNA.
Protein: DHX32_MOUSE
Sequence: MDEEELDHPNASPEKRYFPESLDSSDGDEEGVLACEDLELNPFDGLPYSSRYYKLLKEREELPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLLTSKLSSYYGDVPVIEVRNKHPVEVVYLSGAQKDSFESVIRLIFEIHRSGEKGDVVVFLACEQDIEKTYELVCQEGSNLNPDVGDLVVIPLYPKEKCSLFRPVDETEKRCQVYQRRVVLTTSCGESLIWSHTVKFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEEFASKDMRPLKPAEMQEANLTSMVLFMKRVDIAGLGRCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHGAEEAAVTCWKTFLHPEGDHFTLINVYNAYQDTVLNSANEHCVEMWCHDCFLSCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENGLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSSYSITKKMPEWVLFHQFSISENNYIRVASAVSPELFMQLVPQYYFSNLPPSESKDILQQAAGHLPTETVNKDQDVCDKCPDATEQRCTIQ
What are the official names of this protein?
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32, DEAH box protein 32, MuDDX32.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: P5CR_STAAS
Sequence: MKLVFYGAGNMAQAIFTGIINSSNLDANDIYLTNKSNEQALKAFAEKLGVNYSYDDATLLKDADYVFLGTKPHDFDALATRIKPHITKDNCFISIMAGIPIDYIKQQLECQNPVARIMPNTNAQVGHSVTGISFSNNFDPKSKDEINDLVKAFGSVIEVSEDHLHQVTAITGSGPAFLYHVFEQYVKAGTKLGLEKEQVEESIRNLIIGTSKMIERSDLSMAQLRKNITSKGGTTQAGLDTLSQYDLVSIFEDCLNAAVDRSIELSNVEDQ
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYS2_PSEAE
Sequence: MAVNDYEPGSMVITHVQGGGRDIIQYIPARSSYGTPPFVPPGPSPYVGTGMQEYRKLRSTLDKSHSELKKNLKNETLKEVDELKSEAGLPGKAVSANDIRDEKSIVDALMDAKAKSLKAIEDRPANLYTASDFPQKSESMYQSQLLASRKFYGEFLDRHMSELAKAYSADIYKAQIAILKQTSQELENKARSLEAEAQRAAAEVEADYKARKANVEKKVQSELDQAGNALPQLTNPTPEQWLERATQLVTQAIANKKKLQTANNALIAKAPNALEKQKATYNADLLVDEIASLQARLDKLNAETARRKEIARQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQWQDQTPDSVRYALGMDAAKLGLPPSVNLNAVAKASGTVDLPMRLTNEARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPSTTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVPVYEGATLTPVKATPETYPGVITLPEDLIIGFPADSGIKPIYVMFRDPRDVPGAATGKGQPVSGNWLGAASQGEGAPIPSQIADKLRGKTFKNWRDFREQFWIAVANDPELSKQFNPGSLAVMRDGGAPYVRESEQAGGRIKIEIHHKVRIADGGGVYNMGNLVAVTPKRHIEIHKGGK
What is the function of this protein?
Causes breakdown of chromosomal DNA as well as complete inhibition of lipid synthesis in sensitive cells.
What are the official names of this protein?
Pyocin-S2, Killer protein.
What is the protein family that this protein belongs to?
Belongs to the colicin/pyosin nuclease family.
Protein: ARAA_SALPA
Sequence: MTIFDNYEVWFVIGSQHLYGAETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTSPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKEAHTRIGAWMRQAVSKQDTRQLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSIGDGDISALIDEYESSYTLTPATQIHGDKRQNVREAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKEDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALDLNDMRQFAEIHDIEIAVIDNDTRLPAFKDALRWNEVYYGLKR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: G6PI_CHLTR
Sequence: MMGKGFLDCESLVALQEMALHPIDLTASGCLSEERIQKNSLSAEGFTYSYATERVDDRCLEALQGLTEERELIKQMECMQQGAIMNRIEGFQSESRPVLHTATRAWVRDQDLHEEAAAIARHSKEEALRLAEFLYIARAKFSTLVQMGIGGSELGPKAMYFAMQGSCPSDKRIFFVSNIDPDNAAEVLREIDLEQTLVVVVSKSGTTLEPAANEELFRQAYQNKGLSIAEHFVAVTSQGSPMDDKSRYLEVFHLWDSIGGRFSATSMVGGVVLGFAFGYEAFIEFLQGAAAIDAHALTPKMRENLPLLSAMLGVWNRNLLGYPTTAVIPYSTGLKYFTAHLQQCGMESNGKSISREGKEISFRTSPIIWGDVGTNCQHSFFQSLHQGTDIVPVEFIGFLHNQRGLDCVLSGSSSSQKLFANLVAQSLALAQGRDNANSNKRFKGNRPSSILVAQQLSPRIAGSLLAFYEHKFAFQGFCWGINSFDQEGVSLGKELATQIIGIMSGNAPVEFSEARGMLRLFNVLT
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_BRUA4
Sequence: MAEPGFLSLTLIGALVFGYFLGSIPFGLILTRLAGLGDVRSIGSGNIGATNVLRTGNKKLAAATLIFDMLKGTVAVLVASRYGPDAAIGAGFGAFIGHLFPVWIGFKGGKGVATYLGVLIGLAWPGALVFAAVWIVTALLTRYSSLAALIASIVVPIALYSRGYPAIAVLFAIMTVIVIFKHKANITRLLNGTESKIGAKG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNP_MYCSJ
Sequence: MSVVEIEDGVYESTAVIDNGSFGTRTIRFETGRLAQQAAGAVVAYLDDETMLLSATSASKSPKDHFDFFPLTIDVEERMYAAGRIPGSFFRREGRPSTDAILTCRLIDRPLRPTFVSGLRNEIQVVVTVMSLDPKDLYDVVAINAASASTQIAGLPFSGPVGGVRVALIDGTWVAFPTVEQLERAVFDMVVAGRKTADDVAIMMVEAEATDKVVELVAGGAQAPTEAVVAEGLEAAKPFIKVLCEAQQELAGRAAKPTADYPLFPEYGEDVYYAVASVATDALSEALTIAGKEERNNRTDEIKVEVLGRLADQFAGREKEIGGAFRSLTKKLVRQRILTDHFRIDGRGVTDIRALSAEVAIVPRAHGSALFERGETQILGVTTLDMVKMAQQIDSLGPETSKRYMHHYNFPPYSTGETGRVGSPKRREIGHGALAERALMPVLPSVEEFPYAIRQVSEALSSNGSTSMGSVCASTLSLLNAGVPLKAPVAGIAMGLVSDDVEVDGKTERRFVTLTDILGAEDAFGDMDFKCAGTKDFVTALQLDTKLDGIPSQVLAGALAQAKDARITILEVMAEAIDAPDEMSPYAPRITTIKVPVDKIGEVIGPKGKMINSITEETGASISIEDDGTVFVGASNGEAAQAAIDKINAIANPQLPKIGERFLGTVVKTTDFGAFVSLLPGRDGLVHISKLGRGKRIAKVEDVAKVGDKLRVEIADIDNRGKISLVLVAEEEAAEASDNGSATPSDKAPATADATTAGN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS1_CRYNB
Sequence: MPTDLPYAAEAESSLSPDELEVLRRQYYREIEQGHVTIQSKFNYGWGLIKSPSPELETEGVKLLQEIYSASPDHRRECTYYIAVGYYKLRNYAYARKFNNLLLSVEPGNMQAQSLSTLIENAVKRDGLVGIGMITGAVAVVGLIAGSVWKRSRR
What is the function of this protein?
Has a role in mitochondrial fission.  Has a role in outer membrane fission but not matrix separation (By similarity).
What are the official names of this protein?
Mitochondrial fission 1 protein.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: AMT2_SCHPO
Sequence: MSSVNSIPTATSTVYISVLPATATPSGGSGGNVLHEDLNKFYDYGNTSWILACTPLCLIMVPGVAFFYSGLARRKNTLALIMLSMLGLCVSFFQWYFWGYSLAFSQTGTSGYIGNLRHFAFIRTLADYSPGSNNIPELVFANFQGMFAAITVALFTGAAAERGRIGPMLIITFVWLTVVYCPIACWIWNPNGWAFKFGVYDFAGGGPVEVGSGFAALAYTVCLGRRSKFVEEQFRPHSVLNVVLGTSLLWFGWLGFNGGSAYGSNLRAAMAITNTNLAGAVAGLVWVIYDYIFRTRKWSTIGFCSGVVAGLVAATPCAGFVSPHASLAIGAITGLCCNWAIKLKSHMRIDDAMDIFAIHGVAGFVGTFLNGLFAVDYIAAMDGIYVGENKIRGGWFDHHWRQLGLQMAYICAVGAYDFVVTFIILFITDKIPYLQLRVSPDAEEIGVDADQIGEYAFDYIEERREYKHWKISPAGVPEEIIISNGVAQPTGNVAAPGKILESTNPLELGLTI
What is the function of this protein?
Transporter for ammonium to use as a nitrogen source.
What are the official names of this protein?
Ammonium transporter 2.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: XERC_CHLTA
Sequence: MITSFYAFLDYLKNMKASSLHTLRNYCMDLSSLKCFLEKKSDLSPTPPLSLHDNTYDYPPLSFSLFTKDNIRLYLLEQIQTHHSKRTVRRRLSAIKSFARFCVKNQLIPENPAEMIRGPRLPQELPSPLTYEQVLALMAAPELDKVTGFRDRCLLELFYSSGLRISEITALNRADIDFQSHLLHIRGKGKKERIVPMTKVAVQWLQDYLNHPDRASVEQDHQACFLNRFGKRLSTRSIDRKFQQYLLKTGLSGSITPHTIRHTIATHWLERGMDLKTIQLLLGHTSLETTTIYTHVSMKLKKQIHDETHPHNLEE
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_OENBI
Sequence: MKIRASVRKICTKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUVA_CHLAB
Sequence: MYDYIRGVLTYISSSTMVIESQGLGFSIFAPERWLIELSSQLHRELIVYTYTVVRETEHVLYGFHTRGERECFRMLISFSGVGPKTGLAILNTFSLSQLCSIARAEDIKAIASVPGIGKKTAEKLMVDLKQKLADLLPLDAQILASWEPAKPSCMEEGIQALAALGYPKSSAERMIAEAMSELPDHASVAEILPIALKKNLQGLNKI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CFBC_METAC
Sequence: MKKQKIVAIYGKGGIGKSSTASNVAAACAEAGKKVMIIGCDPKSDSSITLLRGKRIPTILDLLREGVDVQEKDVVFEGYAGVKCVEAGGPEPGIGCAGRGIIVAIQKLKSISGDLLKEQDLIIYDVPGDIVCGGFVAPVRKGYVNEAYVLTSGEYMPLYAANNICKGLSKIGMPLSGVICNSRNASREEEIVRKFSEEIGSQLMAFIPKRQIVQDCEREGYSVMEKAPDSDIAEVYRQLGKSILTNEKKVMASHLSDERLREMTK
What is the function of this protein?
Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes both the six-electron reduction of the tetrahydroporphyrin ring system and the gamma-lactamization of the c-acetamide side chain of Ni-sirohydrochlorin a,c-diamide to yield 15,17(3)-seco-F430-17(3)-acid (seco-F430), the last intermediate in the biosynthesis of the coenzyme F430.
What are the official names of this protein?
Ni-sirohydrochlorin a,c-diamide reductive cyclase complex, component CfbC, NifH homolog component CfbC.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: NQOR_SERP5
Sequence: MAKILVLYYSMYGHIETLAEAVAEGARRVSGVEVTLKRVPETIPAEAFAKAGGKQDQKAPVASPQELADYDGIIFGTPTRFGNMAGQMRTFLDQTGGLWASGALYGKVGSVFSSTGTGGGQEHTITSTWTTLAHHGFIIVPIGYATPELFDVSHVRGGTPYGATTIAGGDGSRQPSQEELTIARYQGEHVAKITAKLKS
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.