PharMolix/UniProtQA huggingface dataset:
Protein: IF3_BORHD
Sequence: MINRSAGKDRDRSRSGDKELRINHKIKAREVRVIFDDGTQSVLPIEDAMRCARDAELDLVEVSPNVLPPVCKIIDYGKYKFHQGKRQKEQRKNQKIIKLKEVRMQPKIDTHDLDFKYRNILGFLKEGNKVKVTIRFRGRELAHTHLGYGILEGILERIGDANYILESPAKMEGKTMFLVIAPKSKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODD1_SINFN
Sequence: MRFKGLDLNLLVALDALMTERKLTAAARSINLSQPAMSAAITRLRTYFRDELFTMNGRELVPTPRAEALAPAVREALLHIHLSIISWDPFNPAQSDRSFRIILSDFMTLMFLERVVVRVAREAPAVSFELLPFSDEPDELLRRGDVDFLILPEMFMSHTHPRAKLFDERFVCVSCPTNQKLPPQLSIDNYVSMGHVAAQFGKQRPSVEEWLLREHGLRRRVEVAVPGFTMIPSFLSGTDRIATLPLRLAMHFAKAIPLRITELPQPIFPAFTEAVQWPAPHSSDPASLWMREIFLQEASRVEFQSETSAHALSKADGAIRHP
What is the function of this protein?
Regulates the expression of the nod abcFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D 1.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: NR1I2_MACMU
Sequence: MEVRPKEGWNHADFVYCEDTEFAPGKPTVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDAAVEERRALIKRKKRERIGTQPPGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCEMPESLQAPSREEAAKWNQVRKDLWSVKVSVQLRGEDGSVWNYKPPADNGGKEIFSLLPHMADMSTYMFKGIINFAKVISYFRDLPIEDQISLLKGATFELCQLRFNTVFNAETGTWECGRLSYCLEDPAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVVQHRVVDQLQEQYAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
What is the function of this protein?
Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds.  Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs.  Response to specific ligands is species-specific, due to differences in the ligand-binding domain.  Activated by naturally occurring steroids, such as pregnenolone and progesterone.  Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 1 group I member 2, Orphan nuclear receptor PXR, Pregnane X receptor.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DLX5_CHICK
Sequence: MTAVFDRRVPGIRSSDFQPPFQSAAAMHHPSQESPTLPESSATDSDYYSPTGAAPHGYCSPTSASYGKALNPYQYQYGMNGSAGTYPAKAYADYGYGSPYHQYGGAYGRGQSSAGQPEKEVAEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLGHHGHGHPPAANPSPGSYLESPSAWYPAASPLGSHLQPHGSLQHPLALPSGTIY
What is the function of this protein?
Transcriptional factor involved in bone development.  Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation.  Binds to DNA.
What are the official names of this protein?
Homeobox protein DLX-5, cDlx.
What is the protein family that this protein belongs to?
Belongs to the distal-less homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOC_LEUPS
Sequence: RIRYKGIVCDRCGVEVTSSKVRRERMGHIELAAPVTHIWYFKGIPSRMGLVLDMSPRSLEEIIYFASYVVIEPGDAPVEKKQMVTEREYRQLKKEYGAGFKAGMGAEAIKELLANVDLAGERDELKRELQEATGQKRVRAVRRLDIVEAFLQSDNKPEWMVMDVVPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVAGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIDVGPFLKMNQMGLPVPMAIELFRPFIMKELTTRKLAGNVKSAKRKIDKADGDVMDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVSGKAMRLHPLVTEAYNADFDGDQMAIHVPLSDEAQAEARLLMLAAGHILAPKDGKPIVAPSQDMVIGNYYLTTEEAGREGEGMIFSGVDEARIAFARKVVHYHTRVGIQTSSFPAEKPFTDEQRSKVMVTSVGKLIFNEILPTDFPFINEPSEDNFKGVDDRFFIESGEDIHDYLAETPIIGAFKKGFLSDIIAEVYKRYKVTETSLLLDRMKDLGYEKSTESGLTVAMTDVTDLKEKPAILEDAHNQVATVTKQFRRGLITDDERYQRVTEIWTKAKDIIQDKLIESFEPTNPIFMMQDSGARGNISNFVQLAGMRGLMAGPGGKIIELPVTANFREGLTVMEMFISTHGARKGMSDTALKTANSGYLTRRLVDVAQDVIVREFDNDSDRGVAVKAIMDGTSVVEPLYDRILGRYAMKSVFDPETGEKIVSRNEMIDEDVAKAIVNAGIEEVTIRSVFTSTTEHGVSVLDYGRNLASGEEVEVGEAVGTVAAQSIGEPGTQLTMRNFHTGGVAGGNDITQGLPRVQEIVEARIPKGRAEISEVTGVVTAIEENPAERTKAVTIEGETDTRTYTLPLTARMRFAEGDEIQRGDAINEGPIDPKELLAVTDTLTTESYMLTEIQK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: DNLI_MYCPA
Sequence: MSPSHAKLATVLLFDVATASADVGGTPSRLTKVARIADLLRRAAPNAALVAIVVSWLSGELRQRQIGVGWAALRSRPPAAAHPTLTVVAVDAAFAEIGAVAGKGAQARRAALLNALFAAATETEQTFLLRLLGGELRQGALAGIMADAVARAAGIPAAAVQRAAMLGGDLPAVAAAALSGEASALDAFTLRVGRPVAPMLAQTAAGVAQAIERHGGQAIFEAKLDGARVQIHRAGDQVTVYTRSLDDVTARLPEVVTATLALPVEALIADGEAIALRPDNSPQRFQVTASRFGRSLDVAAAVAAQPLSVFIFDILHCDGIDLLDAPTTDRLAALDALVPPAQRVDRLLTADPDAAGRFLEATLAAGHEGVMAKAPGAPYQAGRRGAGWLKVKPVHTLDLVVLAVEWGSGRRRGKLSNIHLGARDPATGEFVMVGKTFKGMTDAMLDWQTARFTELAVGGTDGYVVRVRPEQVVEVAVDGVQKSSRYPGGLALRFARVLRYRDDKGPAEADTIDAVRALY
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
Probable DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: MOS_MSVMT
Sequence: VSHVTVPSEGVMPSPLSLCRYLPRELSPSVDSRSCSIPLVAPRKAGKLFLGTTPPRAPGLPRRLAWFSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVNKCTEDLRASQRSFWAELNIAGLRHDNIVRVVAASTRTPEDSNSLGTIIMEFGGNVTLHQVIYDATRSPEPLSCRKQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILISEQDVCKISDFGCSQKLQVLRGRQASPPHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSGEPQYVQYAVVAYNLRPSLAGAVFTASLTGKALQNIIQSCWEARGLQRPSAELLQRDLKAFRGTLG
What are the official names of this protein?
Serine/threonine-protein kinase-transforming protein mos.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: HIS1_YERPB
Sequence: MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_BORBR
Sequence: MSAPLKRTPLAEEHLAAGARMVDFGGWDMPLAYGSQLEEHHAVRQDAGMFDVSHMLNVDVGGADATAFLRRLVANDVARLATPGKALYSCMLNPQGGIIDDLIIYYFAPDQWRVVVNAGTADKDIAWMQRVAAADGFDVAIAPRRDLAMVAVQGPNARAKVWAARPAWQAASEPLAPFSAAAVEAGTLVARTGYTGEDGFEIVLPADAVVQLWRDLLAQGVRPCGLGARDTLRLEAGMNLYGQDMDELVHPDQAGLSWTVALKDEARRFVGRDAIEQFAVPRAFVGLKLQERGVMRAHMPVRCAQGMGELTSGTMSPTLGVSVGFARVPVGVQPGDAVEVEIRGKWVPALVCKLPFVRHGKAVEHS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: GUN11_ORYSJ
Sequence: MSPSSSSSSWRALVLVAAAVLSFSGHVVVAAAAAGHPDYADALAKSILFFQGQRSGRLPPDQAVKWRSNSGLSDGSAANVDLTGGYYDGGDNVKFGFPMAFTTTMLSWGVVEYGGRMRGRVLRDARDAVRWAADYLLRAATATPGVLYVGVGDPDADHRCWERPEDMDTPRAVYSVSASSPGSDVAAETAAALAAASLALRAADPGYSRRLLAAARDVMAFAVRHQGKYSDHVGGDVGAYYASYSGYQDELLWGSAWLLWATRNASYLDYLASLGANDGVDMFSWDNKLAGARVLLSRRALVNGDRRLDAFRRLAEDFICRILPGSPSSTTQYTPGGMMYKSGHANLQYVTSASFLLTTFAKYMAVSNHTFSCQSLPVTAKTLRALARKQVDYILGANPQGMSYMVGYGARFPQRIHHRGASMPSVAAYPAHIGCQEGFSGYFNAGGANPNVHTGAVVGGPDQHDAFPDERGDYDRSEPTTYTNAALVGCLAYFAGSYRS
What are the official names of this protein?
Endoglucanase 11, Endo-1,4-beta glucanase 11, OsGLU4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYREL_METTP
Sequence: MKSIEDLIKKATELKSEGLSEGQISEELNVSRETITWLLTHAERATVPGPKDISVDWSMIGRSAYRLSHIAQALTEMIFDILDEKELDIDIVVGVALSGVPLASMVADHMGVGLAVYMPTKQMASQDVKPHGNLSTNFSDVSGRECVIVDDVITSGRTLEEAVAYLDDRGAKTNVIAVLIDKKGIDSIAGVPVCSLLKVIRVN
What are the official names of this protein?
PyrE-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: SECY_METJA
Sequence: MKKLIPILEKIPEVELPVKEITFKEKLKWTGIVLVLYFIMGCIDVYTAGAQIPAIFEFWQTITASRIGTLITLGIGPIVTAGIIMQLLVGSGIIQMDLSIPENRALFQGCQKLLSIIMCFVEAVLFVGAGAFGILTPLLAFLVIIQIAFGSIILIYLDEIVSKYGIGSGIGLFIAAGVSQTIFVGALGPEGYLWKFLNSLIQGVPNIEYIAPIIGTIIVFLMVVYAECMRVEIPLAHGRIKGAVGKYPIKFVYVSNIPVILAAALFANIQLWGLALYRMGIPILGHYEGGRAVDGIAYYLSTPYGLSSVISDPIHAIVYMIAMIITCVMFGIFWVETTGLDPKSMAKRIGSLGMAIKGFRKSEKAIEHRLKRYIPPLTVMSSAFVGFLATIANFIGALGGGTGVLLTVSIVYRMYEQLLREKVSELHPAIAKLLNK
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY, Protein transport protein SEC61 subunit alpha homolog.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FA10_TROCA
Sequence: MAPQLLLCLILTFLWSLSEAESNVFLKSKVANRFLQRTKRANSLFEEFKAGNIERECIEERCSKEEAREAFEDNEKTETFWNVYVDGDQCSSNPCHYGGTCKDGIGSYTCTCLAGYEGKNCQYVLYQSCRVDNGNCWHFCKPVQNEIQCSCAESYLLGDDGYSCVAGGDFSCGRNIKARNKREASLPDFQTDFSDDYDAIDENNFVETPTNFSGLVPTVQSQNATLLKKSDNPSPDIRVVNGTDCKLGECPWQALLINDQGDGFCGGTILSPIYVLTAAHCINQTKYIRVVVGEIDISRKKTGRLLSVDKIYVHQKFVPSTYDYDIALIQMKTPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRTRERGQTSNTLKVVTLPYVDRHTCMLSSNFPITQNMFCAGYNTLPQDACQGDSGGPHITAYRDTHFITGIISWGEGCAQTGKYGAYTKVSRFILWIKRIMRLKLPSTESSTGRL
What is the function of this protein?
Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
What are the official names of this protein?
Coagulation factor X.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VPS10_CANAW
Sequence: MRNNWNWLIFLVPFILSLTTAYTPDISVVKNKSPAREIKYFDDSSNLLVLRDEHLLISKNDGKSFEEIPDIKDPIIYFEMDPTNKNRAFAMTLSQKQYITEDQGNKWRTFEIDIFNGEMASIPKITFNFENPNYLMISNYECPEGQRLNRNCKHRYFFTKDGFKSKPNKLPVDAHVCRFAKSTKTSKIGKSETIFCTVNQLNSYGHIVESHLYNSNDFFQNKNEIKIKPLDSSSGEIIDVKIEEDFMIVVSRMDKFNEKSLINAYVSRDGENFVRADLDIDIKYGVMSFLPSSVSSLFLTIMDFNSRAFQTASFYGSDSSGLHFTKLLDNVAGGNIQKIENIDGAWIANIGVDSNNPYDGDESLLDNLFGGTYAKSIVSKVSINDGKDWSLIKLNDNSCKIEDECSLHLWDFTELDGEGKFVTGPTPGILLGVGNKGKNLAHEFEKMKTYVSRDGGVTWNKALDFPAVFAFGDQGNVILAVPYNGKKKYEAAKHFYFSLDQGKSWEKVDLEHPIYPLSILTTIDGTSRKFIIGGIDDSRRAENEYIYSVDFTNAFDGKTCGDDDFEEFVARKSNDNGNDEPLCVYGHREKFRRRKQDAKCFVNKLFEDIKVIEDPCQCTEHDFECGPGFRLSEKESTNVCVPDRKQLTQLCQSKSEITLPNKVLVEGNKCNMGDKKLEDFVSQETLKCSDYVDNGGDGNGDEKNPNQGDSNQIEVHINDFEGKLSQYQYIAESKDNNAADNVVIKTMDDRLWISNNGGVSFVRVPISDKILGFYAGPIPGQITLITATNIIYVSDDGGATFIKRKVPTQPSPRVDRAIAFHSKNVERFIWFGEECESNGRCTSNAYITDDAGATFNKLMANVRTCDYVGAVLESGDHELIYCSGQNSLDNNNNNNKNKNKLALFSLKESSSEEPKKIFENIVGYAITGTYVVVATIDDKTDSLLSKVTVDGDIFADADFPHDLKVEPHQAFTVLDSSSKAVFMHVTTNEKPNFEYGQLLKSNSNGTYFVLTLDNVNRNTVGYVDFDKIDGLEGTIIANVVANAQANEGTKNLQTLISHNDGSEWDKLVPPTIDSEGIKYPCTGQSLNKCALHLHGFTERADYRDTFSSGSATGFLIGVGNVGEFLTPMDDPSTATFLSTDGGVTWKEIKKGVYMWEYGDQGTILVLVNAVENTDVLYYSLDEGQTWKEYKFSEYKVNIYDLATVPTDTARKFIIFAENPKDHRDIQTFTIDFTNIYPRQCQLNLDDPEHDDYEYWSPTHPIGGDKCIFGHESKYLRRAKGHTDCFIGSAPLSEGYKLEKNCSCTRRDYECDYNYVRDVNDNTCKLVKGMTSADRKTTMCSKENAFQYFESTGYRKIPLSTCKGGQQFDNWNPKPCPGKEKQFNEYYGREVKGHKLFFLIFIPLIIFLATVLFVYDRGIRRNGGFKRLGQIRLNDDDDDFNPIENDQIDVVVNKIVKGGVYTVAVLIATVKTIRKIDRMMLEKLGNVIFRRSPGRRNYVSVPNDLDEEEELFGDYQDNLDDELEDAVFNQDDNLVRTPFADDVEEEEEEREGEGEGEQSNPSDERLFDIDDNEDEDEQHEVNKPTTS
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: MURC_ECO81
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYDDFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEMLAPVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_DESVV
Sequence: MLYNLLYPLSSDITVFNVFRYITFRSAWALATALLVSIVVGPRFIAWLQRLKCRQFIHEDVTCHMSKAGTPTMGGLLIGFAVTFSVLLWADLRNPYIWLTLLVFTGFGFIGFLDDYTKLRRRNNKGLTASAKFLWQVGVAVAAMYLLVQLPAYSTKLAFPFFKGLTPDLGWLYIPFAVAVMVGSSNGVNLTDGLDGLAIGPTIVAGIVFSIFIYVAGHSQIAGYLQVPYVPGVGEVAVFCGALVGAGLGFLWFNAYPAQVFMGDVGSLSLGGTLGFLAVLCKQELLLLVVGGLFVVETLSVILQVGYFKFSGGKRIFRMAPLHHHFELQGIPESKIIIRFWITSALLGLIALSVLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL15_SHEB9
Sequence: MRLNTLSPAAGSKHAPKRVGRGMGSGLGKTAGRGHKGQKSRSGGGVRPGFEGGQMPLKIRLPKFGFTSRRAMVTAEVRVLELAKVNGDVIDLNALKDANVITRNIQFAKIVLSGTIERPVTVKGLKVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: NANO3_HUMAN
Sequence: MGTFDLWTDYLGLAHLVRALSGKEGPETRLSPQPEPEPMLEPDQKRSLESSPAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATRERAHTRRFCPLTGQGYTSVYSHTTRNSAGKKLVRPDKAKTQDTGHRRGGGGGAGFRGAGKSEPSPSCSPSMST
What is the function of this protein?
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase.  Affects cell proliferation probably by repressing translation of specific mRNAs.  Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways.  Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
What are the official names of this protein?
Nanos homolog 3, NOS-3.
What is the protein family that this protein belongs to?
Belongs to the nanos family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body. Note=Co-localizes with PUM2, EIF2S1 and TIAL1 in the stress granules. Co-localizes with DCP1A in the P-body.
Protein: BIMC_EMENI
Sequence: MAGPQRATSGLPTRRTTTRQPTRRAGSAIPERQTSTASPAVSTKTAAISRTRTLKSPGEPASVLAKRKERDIEREINEDTSIHVVVRCRGRNEREVKENSGVVLQTEGVKGKTVELSMGPNAVSNKTYTFDKVFSAAADQITVYEDVVLPIVTEMLAGYNCTIFAYGQTGTGKTYTMSGDMTDTLGILSDNAGIIPRVLYSLFAKLADTESTVKCSFIELYNEELRDLLSAEENPKLKIYDNEQKKGHMSTLVQGMEETYIDSATAGIKLLQQGSHKRQVAATKCNDLSSRSHTVFTITVNIKRTTESGEEYVCPGKLNLVDLAGSENIGRSGAENKRATEAGLINKSLLTLGRVINALVDKSQHIPYRESKLTRLLQDSLGGRTKTCIIATISPARSNLEETISTLDYAFRAKNIRNKPQINSTMPKMTLLREFTAEIEKLKAELIATRHRNGVYMSVESYEEMKMENESRRIISEEQRAKIESMESSLRHKVQELLTLTSKFNDLKKDNDDTLAALCSTNDVLQQTDIVLQNTRAQLEEEEMLRCAHEETEHQLQDVGKGLISTLGQTVEDINSLQSKLDRKAELDATNAELWRASSTEVSDVTKRIDQRVEAFQTRHAKLLETTSVKVNEFIATEISNIERTRSDLSEYNRSLDAACNNAKAETSSAHEDMNNVLEEIKDLREEVKSKVGEGLNGLSAAAARISEEVIGEFTQLHSQLHTSFNNLGKDLKSIFETMATHLSEQKNEINRLRAELQSSNRQNIETTHKASAHLAQAIEEEHVAAEAEREILMSQIKALVEESRQKQFARLRAKIDGVRTEISASGDMLEQATTQHDRQIDEWVFKSEQFAKDVNASKDEIRTKLQNDWEAFDQRNSTIRKATESVHKETVRIVDVQVDDMGRQMEALDDFVAKARSQNGRYRDAHIATLDTIATGVRDSYSSIEGRVENLTGRMNQFQQEATHHHATLEESIAPLSNDVRKPLTDLSSSFQNRSLEEYVATGVTPKKRKYDYISVLPSTESHEVLKSRLRTTKEMEVLPFNSDDQLSGPSSSPGGSPSKGFVYNDVEDEVGTHAPTVTNVNPSNTGLREVDANVAARPLVYSTGEKSTDQDGSPVVSPDSATEAEGMNGPPSKRRRSNSVVADTKLPNKMLARRMAGMMEGRENVPPPGISNGRRLRGRPSP
What is the function of this protein?
Important role in mitotic dividing cells.  Microtubule motor required for spindle body separation.
What are the official names of this protein?
Kinesin-like protein bimC.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RPOZ_BURM9
Sequence: MARITVEDCLKQIPNRFELALAATYRARQLAQGHTPKIESRDKPTVVALREIAAGQVGVEMLKKVPA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: HEY2_MOUSE
Sequence: MKRPCEETTSESDLDETIDVGSENNYPGHATSSVMRSNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALATDFMSIGFRECLTEVARYLSSVEGLDPSDPLRVRLVSHLSTCASQREAAVMTSSMAHHHHPLHPHHWAAAFHHLPTALLQPNGLHTSESTPCRLSTSSEVPSAHGSALLTATFAHADSALRMPSGGTVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPSNAAAAAAVAAATAISPPLSVSAASSPQQTSTGTNNKPYQPWGTEVGAF
What is the function of this protein?
Transcriptional repressor which functions as a downstream effector of Notch signaling in cardiovascular development.  Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development.  May be required in conjunction with HEY1 to specify arterial cell fate or identity.  Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification.  Binds preferentially to the canonical E box sequence 5'-CACGTG-3'.  Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3.
What are the official names of this protein?
Hairy/enhancer-of-split related with YRPW motif protein 2, HES-related repressor protein 2, Hairy and enhancer of split-related protein 2, HESR-2, Hairy-related transcription factor 2, HRT-2, mHRT2, Protein gridlock homolog.
What is the protein family that this protein belongs to?
Belongs to the HEY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPB_ECO45
Sequence: MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASDVMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEASDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVEEKALADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BTBDJ_BOVIN
Sequence: METPGLVVHGEAAPFSTALRSLVNNPLYSDVRFVVGQERQEVFAHRCLLACRCNFFQRLLSSEPGPGVPSPVVLSTVPAEAFLAVLEFLYTNSAKLQRHSVLEVLTAAVEYGLEELRELCLEFVVKALDVELVCEALQVAVTFGLGQLQERCVAFIEAHSQETLRTRGFLELSAPALLPLLRSDKLCVDEAELVLAARSWARVGAAVLERPVAEVAAPVVRELRLALLAPAELSALEEQNRREPLIPVEQIVEAWKCHALRRGDAARGTPCRRRRGTLPREHHRFLDLPFK
What are the official names of this protein?
BTB/POZ domain-containing protein 19.