PharMolix/UniProtQA huggingface dataset:
Protein: LT_POVK3
Sequence: MDKTLSREEAKQLMQLLCLDMSCWGNLPLMRRQYLVKCKEYHPDKGGNEESMKLLNSLYLKLQDSVSSVHDLNEEEDNIWQSSQIPTYGTPDWDEWWSQFNTYWEEELRCNESMPSSPKRSAPEEEPSCSQATPPKKKHAFDASLEFPKELLEFVSHAVFSNKCITCFVVHTTREKGEVLYKKLLQKYQCSFISKHAFYNTVLIFFLTPHKHRVSAINNFCKGHCTVSFLFCKGVNNPYGLYSRMCRQPFNLCEENIPGGLKENEFNPEDLFGEPKEPSLSWNQIANFALEFDIDDVYYLLGSYIRFATKPEECEKCSKNDDATHKRVHVQNHENAVLLQESKSQKNACTQAIDRVIAERRYNCVTLTRKKLLTKRFKKLFNEMDKIVVGERKILLYMASIAWYTGLNKKIDELVVRFLKLIVDNKPKHRYWLFKGPINSGKTTLATALLNLCGGKALNINIPSEKLPFELGVALDQYMVVFEDVKGQIGIEKHLPSGNGVNNLDNLRDYLDGCVEVNLEKKHVNKRSQIFPPGIVTMNEYCIPETVAVRFEKTVMFTIKRNLRESLEKTPQLLSQRILHSGIAMLLLLIWYRPVSDFDEEIQSNVVYWKEVLDNYIGLTEFATMQMNVTNGKNILEKWFE
What is the function of this protein?
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation.  Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA.  Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.  Participates in the modulation of cellular gene expression preceeding viral DNA replication.  This step involves binding to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53.  Induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes.  Inhibits host TP53 binding to DNA, abrogating the ability of TP53 to stimulate gene expression.  Plays the role of a TFIID-associated factor (TAF) in transcription initiation for all three RNA polymerases, by stabilizing the TBP-TFIIA complex on promoters.  Initiates viral DNA replication and unwinding via interactions with the viral origin of replication.  Binds two adjacent sites in the SV40 origin.  The replication fork movement is facilitated by Large T antigen helicase activity.  Activates the transcription of viral late mRNA, through host TBP and TFIIA stabilization.  Interferes with histone deacetylation mediated by HDAC1, leading to activation of transcription.
What are the official names of this protein?
Large T antigen, LT, LT-AG.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CENPS_MOUSE
Sequence: MEEVEAEEPQEFSHRQRLKAAVHYTVGCLCQEVTLNKQVNFSKQTIAAISEVTFRQCENFAKDLEMFARHAKRSTVTTEDVKLLARRNNSLLKYITEKNEEIAQLNLKGKAKKKRKPEDESRSSRESMAEELDGAEELQSES
What is the function of this protein?
DNA-binding component of the Fanconi anemia (FA) core complex.  Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage.  In complex with CENPX (MHF heterodimer), crucial cofactor for FANCM in both binding and ATP-dependent remodeling of DNA.  Stabilizes FANCM.  In complex with CENPX and FANCM (but not other FANC proteins), rapidly recruited to blocked forks and promotes gene conversion at blocked replication forks.  In complex with CENPT, CENPW and CENPX (CENP-T-W-S-X heterotetramer), involved in the formation of a functional kinetochore outer plate, which is essential for kinetochore-microtubule attachment and faithful mitotic progression.  As a component of MHF and CENP-T-W-S-X complexes, binds DNA and bends it to form a nucleosome-like structure.  DNA-binding function is fulfilled in the presence of CENPX, with the following preference for DNA substates: Holliday junction > double-stranded > splay arm > single-stranded.  Does not bind DNA on its own.
What are the official names of this protein?
Centromere protein S, CENP-S, Apoptosis-inducing TAF9-like domain-containing protein 1 homolog, FANCM-interacting histone fold protein 1.
What is the protein family that this protein belongs to?
Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Assembly of CENPS and CENPX and its partner subunits CENPT and CENPW at centromeres occurs through a dynamic exchange mechanism. Although exchange is continuous in the cell cycle, de novo assembly starts principally during mid-late S phase and is complete by G2. CENPS is more stably bound at the kinetochore than CENPX. During S phase, rapidly recruited to DNA interstrand cross-links that block replication. Recruited to DNA damage sites about 20 minutes following UV irradiation, reaching a plateau after approximately 40 minutes.
Protein: FLGH_PSET1
Sequence: MRNIILFAAGTLLLSGCVSTQNSDVVQDDPYYAPMYPEPNVEPAVANGSLFNTYLSNDLYADKKALRTGDIITVKLQESTQASKAAKTETDKQSDAKLDPVIGLGGLPVNIGGDSIQFGIGSDASFKGDSKSNQSNSLAGDISVNVMRVLPNGNLVIRGEKWLTLNSGEEFIRLEGLVRPEDVTADNTVQSNRIANARIQYSGKGQTQEAQSAGWLTRFFSSSLFPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: RFLB_RAT
Sequence: MVGRLSLQDVPELVDTKKKGDGVLDSPDSGLPPSPSPSHWGLAAATGGGGERAPVAGTLEPDATVTSVVPNPASLSHSLAGICSPRLCPLSFGEGVEFDPLPPKEIKYTSSVKYDSERHFIDDVQMPLGLVVASCSQTVTCIPNCTWRNYKAEVRFEPRHKPARFLSTTIIYPKYPKTVYTTTLDYNCHKKLRRFLSSVELEATEFLGSDGLLDEC
What is the function of this protein?
Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins.  Plays an essential role in the formation of cartilaginous skeletal elements.
What are the official names of this protein?
Refilin-B, Regulator of filamin protein B, RefilinB.
What is the protein family that this protein belongs to?
Belongs to the Refilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with FLNA along actin bundle-like structures.
Protein: PSAA_PIPCE
Sequence: MIIRSPESEVKIVVDRDPVKTSFEEWAKPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQLWRASGITNELQLYCTAIGALVFAGLMLFAGWFHYHKAAPKLSWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLDAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPLFTLNWSKYAEFLTFRGGLDPTTGGLWLTDIVHHHLAIAILFLIAGHMYRTNWGIGHSLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWIQNTHALAPSATAPGAIASTSLTWGGADLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIVQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PAXI1_XENLA
Sequence: MAEDEVKVPEDMFKDVKFYPVGDLDPKVVQMLKAGKAKEVSYNALATHIIAEDGDNPEVGEAREVFDLPVVKPSWVILSVRCGVRLPENGFSPESGQIFFGVTACLSQVSPDDRNSLWALTTFYGGDCQLSLNKKCTHLIVPEPKGNKYEYAFQRGSIKIVTPDWVLDSVSEKTKKDEALYHPRLIVYEEEEEEEEEEAENEEQESQNGSDEDKYSSKSSPVTSRDGSPVHNRESSPKRSSSDKIKSELMFDDSSDSSPEKQERNLNWTPAEVPQMSTAKRQLHQGAPGSERPDMMAFRSPAVRTLRNITNSADVQQVNRPSNVAHILQTLSASTKSLEQRVNHPQQGHPNAVLFGQVKPLTSEAQHLIQQSHQPHHQQQQQQQNHPIVQLQPQQLLQLQQQQQQITQQVFPQHQFPQVNQQHPFTQLQFPQQQLHPQQQLHRPQQQTIQHFQQQHALQQQLHQLQQQHLQPKPQTLQQNMQQQNLQQPNLQQILQHQQTIQQTPSQQQALQPAIQQQQMLQPNIQQQQTLQSNLQQQTLQPIIQQQQGLQQQNLQQSLQQIQQQMQHLTPQQKQQIQQQQQQMLQKQQLQSQSLQQQQMQTHVLQQQQIQTQALQQQQQIQNQALQQPQQNQVQTHALQQHRLQSQTLQQQHHVQGQTVQQQTHQLQTQTLQQQHQIQTLQIPHQIPAPNQQHQIPPQMLQQQTLQLQQQMQPQIQQPQMQSGVQQQSSLQPQQMQQHKHNLQQVQHQLQQLQQQRMQQRQMALPQQIANQQPPQPHQLHGHDPSVEIPEDFFLLGCVFAIADYPEQMPDKQLLATWKRIIQTHGGTVDAALSSRCTHLLCESQVSSMYAQALKERKRCITAHWLNAVLKKKKMVPPYRALHFPVAFPPGGKPCSQHIISVTGFVDSDRDDLKLMGYLAGAKYTGYLCRSNTVLICKEPSGLKYEKAKEWRIPCVNALWLCDILLGNLEALRQIQHSRYTVFNLQDPLAPSPHLVTDDLLDAWRMPLKVSSEVLMSIRMPLKPKQNEPAVQPKRPRIEDIPPPTKKLSPDQTPHVIFTGFDPLQVQQYIKKLYILGGEVADTAQKCTHLVANKVTRTVKFLTAISVAKHIVTPEWLDESFKSQKFAEEQNYILRDAEAEVLFCFSLEESLKKAHVNPLFKGKYFYITPGICPSLSTMKAIVECAGGKILTKQPSFRKIMEHKQNKRLAEIILISCENDLHLCREYFAGSVDVHNAEFVLTGVLTQALDYESYKFT
What is the function of this protein?
Involved in DNA damage response.  Promotes ubiquitination of PCNA following UV irradiation and may regulate recruitment of polymerase eta and rad51 to chromatin after DNA damage.  May function as transcriptional cofactor in TGF beta signaling.  Accentuates smad2-dependent transcription.
What are the official names of this protein?
PAX-interacting protein 1, PAX transactivation activation domain-interacting protein, SMAD wing for transcriptional activation, Protein Swift.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_STAA1
Sequence: MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PSA_MYCBT
Sequence: MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALGIAVAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQESPQSDGESSG
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_TERTT
Sequence: MSLRIYNTATRQKEDFVPVDPAAIKMYVCGPTVYNLVHIGNARPVVVFDTLFRVLQYLYDNVIYARNITDIDDKIMKAAAENGEPISALAARYAAEYERDMAQLNALQPTIVPYATEHLEQMIAMTQALVNKGHAYAADGHVLFDVQSMGDYGELSNRSLEDMLDGARVEVAPYKKYAGDFVLWKPSADAEPGWESPWGRGRPGWHLECSAMIEKHLGNTIDIHGGGRDLIFPHHENERAQSQCAHDGEQYVKYWMHNGYINIDGEKMSKSLGNFRTVRELLESFPGEVIRFALLSAQYRSELDFSAELLEQSKASLDSLYGALRKTEEEILPAGPALAASPGFAALMDDLNTPLAISELHQLARTVHKAEPESEEAQSAKGMMLALANLMGLLQEDPETWFQGGAEQDVSWIEALIAERQQAKLDKQYARADEIREELKAKGILLEDSREGTTWKKA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_SALAR
Sequence: MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVSVEAADSFSLNNLGRFADKLPPEPRENIVYQCWERFCHALGKTIPVAMTLEKNMPIGSGLGSSACSVVAALVAMNEHCGKPLNDTRLLAMMGELEGRISGSVHYDNVAPCFLGGMQLMIEENGIISQQIPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPQLAAALMKDVIAEPYRARLLPGFSQARQAVAEIGALASGISGSGPTLFALCDKPETAQRVADWLSKHYLQNQEGFVHICRLDTAGARVLG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_PARPJ
Sequence: MIKQALISVSDKSGIVDFAKSLSDLGVKILSTGGTAKLLADAGLSVTEVADYTGFPEMLDGRVKTLHPKVHGGILARRDLPEHMAALEKHDIPTIDLLVVNLYPFVQTVSKEECSLEDAIENIDIGGPTMLRSAAKNHRDVTVVVDPADYAVVLDEMRANSNAVSYKTNFRLATKVFAHTAQYDGAITNYLTSLTDELQHSSRNTYPATFNLAFDKVQDLRYGENPHQSAAFYRDLSVPAGALANYNQLQGKELSYNNIADSDAAWECVKTFDVPACVIVKHANPCGVALGADAHDAYAKALQTDPTSAFGGIIAFNREVDEAAAQAVAKQFVEVLIAPSFSAEARQVFAAKQNVRLLEIALGEGHNAFDLKRVGGGLLVQSLDSKNVQPHELRVVTKRHPTPKEMDDLLFAWRVAKFVKSNAIVFCGNGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVVVAAGASCVIQPGGSMRDDEVVGAADEHNIAMVLTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: UVRB_HAEI8
Sequence: MSEKINTKPFILHSDFRPSGDQPQAIEKLAENLTDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYAEMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYLQMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSFGAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGYCSGIENYSRYLSGRNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSATPGPYELEKSGTEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYADSITKSMEKAITETNRRREKQIKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQQIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCAS_AGRSK
Sequence: MTRQMILAVGQQGPIARAETREQVVVRLLDMLTKAASRGANFIVFPELALTTFFPRWHFTDEAELDSFYETEMPGPVVRPLFEKAAELGIGFNLGYAELVVEGGVKRRFNTSILVDKSGKIVGKYRKIHLPGHKEYEAYRPFQHLEKRYFEPGDLGFPVYDVDAAKMGMFICNDRRWPEAWRVMGLRGAEIICGGYNTPTHNPPVPQHDHLTSFHHLLSMQAGSYQNGAWSAAAGKVGMEENCMLLGHSCIVAPTGEIVALTTTLEDEVITAAVDLDRCRELREHIFNFKQHRQPQHYGLIAEL
What is the function of this protein?
The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics.  Industrial production of beta-lactam antibiotics is now being developed using this enzyme.
What are the official names of this protein?
N-carbamoyl-D-amino acid hydrolase, D-N-alpha-carbamilase.
Protein: RPOA_DESVH
Sequence: MLIKQGDRLINTRNWSELVKPEQISRDGEVSDTMYGKFVCEPLERGYATTIGNAMRRVLLSSLQGAAFVAVKISGVQHEFTTIPGVLEDVTDVVLNLKQVRLAMDTEEPQYLELKVDKRGAITAGDVRTNQHVMVLNPDQHIATLTEDIELTFELEVRMGKGYVPADMHEGLSEEIGLIKLDASFSPVRKVAYTVEQARVGQMTNYDKLILEVWTDGSVSPEDAIAYSAKIIKDQISVFINFDERISGENSNGSADSGEFNEHLFKSIDELELSVRATNCLKSANIALVGELVQKSENEMLKTKNFGRKSLDEIRRVLGDMGLDFGTKVDGFEKKYQEWKRKQQHEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: FUMC_AGRFC
Sequence: MTATRTETDTFGPIEVQADRYWGAQAQRSLGNFKIGWEKQPASVVRALGIVKQAAARANMALAGLDPKVGDAIIAAAQEVIDGKLTEHFPLVVWQTGSGTQSNMNANEVISNRAIEMLGGEMGTKKPVHPNDHVNMSQSSNDTYPTAMHIACVEEIVHHLLPALKHLHTALEAKVKQFEKIIKIGRTHTQDATPLTLGQEFSGYAAQVASAIANIELTLPALSKLAQGGTAVGTGLNAPVGFAEKVAEEISEITGLSFVTAPNKFEALASHDSMVFSHGAINAAAAALFKIANDIRFLGSGPRAGLGELSLPENEPGSSIMPGKVNPTQSEALTQVCAHIFGNNAALSFAGSQGHFELNVYNPMMAYNFLQSVQLLGDAAVSFTDNCVVGIEAREDNIRKGVENSLMLVTALNGKLGYDICAKIAKTAHKNGTTLREEAVGGGYLTNEEFDQYVRPENMIGPK
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QOX4_STAAM
Sequence: MSTIMKHTVGFIASIVLTLLAVYVTLYTSLTFHAKLTIIFGFAFVQAGLQLLMFMHLTEGKDGRLQTFKVIFALVITLCFVVGTYWVMQGGHSSHL
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
What are the official names of this protein?
Probable quinol oxidase subunit 4, Quinol oxidase polypeptide IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS12_WOLSU
Sequence: MPTINQLIRKERKKAIKKSKSPALVNCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSGFEVISYIPGEGHNLQEHSIVLIRGGRVKDLPGVKYHIIRGALDTAGVQKRNVSRSKYGAKKGKAGAAPTTGKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PDS_SYNE7
Sequence: MRVAIAGAGLAGLSCAKYLADAGHTPIVYERRDVLGGKVAAWKDEDGDWYETGLHIFFGAYPNMLQLFKELNIEDRLQWKSHSMIFNQPTKPGTYSRFDFPDIPAPINGVAAILSNNDMLTWEEKIKFGLGLLPAMIRGQSYVEEMDQYSWTEWLRKQNIPERVNDEVFIAMAKALNFIDPDEISATVVLTALNRFLQEKKGSMMAFLDGAPPERLCQPIVEHVQARGGDVLLNAPLKEFVLNDDSSVQAFRIAGIKGQEEQLIEADAYVSALPVDPLKLLLPDAWKAMPYFQQLDGLQGVPVINIHLWFDRKLTDIDHLLFSRSPLLSVYADMSNTCREYEDPDRSMLELVFAPAKDWIGRSDEDILAATMAEIEKLFPQHFSGENPARLRKYKIVKTPLSVYKATPGRQQYRPDQASPIANFFLTGDYTMQRYLASMEGAVLSGKLTAQAIIARQDELQRRSSGRPLAASQA
What is the function of this protein?
This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.  Also active with phytofluene and 1,2-epoxyphytoene as substrates.
What are the official names of this protein?
15-cis-phytoene desaturase, Phytoene dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UPPP_ECO81
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ANKL2_DROME
Sequence: MSTYFGVYIPTSKAGCFEGSVSQCIGSIAAVNIKPSNPASGSASVASGSPSGSAASVQTGNADDGSAATKYEDPDYPPDSPLWLIFTEKSKALDILRHYKEARLREFPNLEQAESYVQFGFESIEALKRFCKAKPESKPIPIISGSGYKSSPTSTDNSCSSSPTGNGSGFIIPLGSNSSMSNLLLSDSPTSSPSSSSNVIANGRQQQMQQQQQQQPQQPDVSGEGPPFRAPTKQELVEFRKQIEGGHIDRVKRIIWENPRFLISSGDTPTSLKEGCRYNAMHICAQVNKARIAQLLLKTISDREFTQLYVGKKGSGKMCAALNISLLDYYLNMPDKGRGETPLHFAAKNGHVAMVEVLVSYPECKSLRNHEGKEPKEIICLRNANATHVTIKKLELLLYDPHFVPVLRSQSNTLPPKVGQPFSPKDPPNLQHKADDYEGLSVDLAISALAGPMSREKAMNFYRRWKTPPRVSNNVMSPLAGSPFSSPVKVTPSKSIFDRSAGNSSPVHSGRRVLFSPLAEATSSPKPTKNVPNGTNECEHNNNNVKPVYPLEFPATPIRKMKPDLFMAYRNNNSFDSPSLADDSQILDMSLSRSLNASLNDSFRERHIKNTDIEKGLEVVGRQLARQEQLEWREYWDFLDSFLDIGTTEGLARLEAYFLEKTEQQADKSETVWNFAHLHQYFDSMAGEQQQQLRKDKNEAAGATSPSAGVMTPYTCVEKSLQVFAKRITKTLINKIGNMVSINDTLLCELKRLKSLIVSFKDDARFISVDFSKVHSRIAHLVASYVTHSQEVSVAMRLQLLQMLRSLRQLLADERGREQHLGCVCASLLLMLEQAPTSAVHLPDTLKTEELCCAAWETEQCCACLWDANLSRKTSRRKRTKSLRAAAVVQSQGQLQDTSGSTGSSALHASLGVGSTSLGASRVVASASKDAWRRQQSDDEDYDSDEQVIFFDCTNVTLPYGSSSEDEENFRTPPQSLSPGISMDLEPRYELFIFGNEPTKRDLDVLNALSNVDIDKETLPHVYAWKTAMESYSCAEMNLFPSPRNVKVQKPEPWYSGTSSSHNSQPLLHPKRLLATPKLNAVVSGRRGSGPLTAPVTPRLARTPSAASIQVASETNGESVGTAVTPASPILSFAALTAATQSFQTPLNKVRGLFSQYRDQRSYNEGDTPLGNRN
What is the function of this protein?
Involved in brain development probably by regulating asymmetric division of neuroblasts (PubMed:31735666, PubMed:30550790, PubMed:25259927).  Regulates neuroblast asymmetric cell division by controlling asymmetric protein localization of Mira, Baz, Par-6 and aPKC, and spindle alignment (PubMed:31735666).  Also, regulates the localization of kinase Ball during mitosis, specifically maintaining Ball in the nucleus during interphase (PubMed:31735666).  Required for proper ER and nuclear envelope morphology in neuroblasts (PubMed:31735666).
What are the official names of this protein?
Ankyrin repeat and LEM domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the ANKLE2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Nucleus envelope. Cytoplasm. Note=In neuroblasts, recruited to the nuclear envelope at the initiation of mitosis and remains associated with it until the beginning of cytokinesis.
Protein: AMPA_SHEDO
Sequence: MEFSVKSGSPEKQRSACIVVGVYEPRRLSGIAEQLDKISEGYISNLLRRGDLEGKPGQMLLLHHVPNVLSERVLLVGCGKERELDERQYKQIITKTISTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVETTQASLYSFDALKTRKGETRRPLRKMVFNVPTRKELTIGERAVEHGMAVSAGMHLCRDVANMPPNICNPAYLASQARQMAETHDKLKVTTIGEEQMAKLGMNSYLAVGRGSSNESIMTVMEYKGAVDSADKPIVLVGKGLTFDSGGISLKPGEAMDEMKYDMGGAAGVIGAMKALCEMNLPINVIGILAGCENMPSGNSYRPGDILTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPELVIDTATLTGACVIALGKHASGLFSSHNPLAHELLNAGEQSGDRAWRMPLWEEYQDMLDSPFADMTNLGGRPAGSITAACFLSRFTKKYNWAHLDVAGTAWNSGANKGSTGRPVPILSQFLINRSGVEISE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_PSEA8
Sequence: MRLRLFLAASALALLSGCAGLTSHEALEGQGDAQTWKTHKQQLSELDAWQIDGKVGIRAPRDSGSGTLFWLQRQGYYDIRLSGPLGRGAARLTGREGAVSLEVAGQGRYQAESPEALLEEQLGWRLPVSHLLWWVRGLPAPDSKSRLTLDADSRLARLEQDGWQIEYTRYAEQNGYWLPERLKLHGQDLDVTLVIKDWQPRQLGR
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.