PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_HUMAN
Sequence: MPSCGACTCGAAAVRLITSSLASAQRGISGGRIHMSVLGRLGTFETQILQRAPLRSFTETPAYFASKDGISKDGSGDGNKKSASEGSSKKSGSGNSGKGGNQLRCPKCGDLCTHVETFVSSTRFVKCEKCHHFFVVLSEADSKKSIIKEPESAAEAVKLAFQQKPPPPPKKIYNYLDKYVVGQSFAKKVLSVAVYNHYKRIYNNIPANLRQQAEVEKQTSLTPRELEIRRREDEYRFTKLLQIAGISPHGNALGASMQQQVNQQIPQEKRGGEVLDSSHDDIKLEKSNILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNSRKLRGETVQVDTTNILFVASGAFNGLDRIISRRKNEKYLGFGTPSNLGKGRRAAAAADLANRSGESNTHQDIEEKDRLLRHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEKTLVQILTEPRNAVIPQYQALFSMDKCELNVTEDALKAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSDIVCVEVDKEVVEGKKEPGYIRAPTKESSEEEYDSGVEEEGWPRQADAANS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease complex.  Hydrolyzes ATP (PubMed:28874591).  Targets specific substrates for degradation by the Clp complex (PubMed:11923310, PubMed:22710082).  Can perform chaperone functions in the absence of CLPP.  Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure (PubMed:22841477).  ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis (PubMed:28874591).  Important for efficient erythropoiesis through up-regulation of heme biosynthesis (PubMed:25957689, PubMed:28874591).
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein: YEQ6_YEAST
Sequence: MTSGYYTVSFFYAILLLCACTRAEIYLTGGESQGLPSGFWQMDDDLAIAPVSMVEFYQTIGLTANGTVPESFNKRDATEYPNIISNITTQAANFTQHSLVEQLQNDVTAISISNAINVAVDGSVETPADLQYNRNQETGESTLCRAKFYGVEVRTWSRLYNRAVSSTTLTTNLNSYIAQWVAWAVHGSGDKKFCGSQEFTNIFFDGQEGWSLFVKTWSTNSSCDITASEGNLTCAVRVSVSSMHNHGKTAFCVTYSHGDSWRAELRVVANDAWSHYYPWSIDCPEVDKNNMAINDCFDQAQG
What are the official names of this protein?
Putative uncharacterized protein YER076C.
What is the protein family that this protein belongs to?
To yeast killer toxin KHR.
Protein: DUT_LEPIC
Sequence: MKIFVQKLRPNAELPLLQTKQAAGYDIHACLDSKLVLEPGNVGLVPTGLSFAIPQEFHFEIRPRSGFSTKNRILIPNSPGTIDSDYRGELMIPLLNLGDSSFIIEHGMRIAQLLIRKTWYADWELVSEFADRTERGANGFGSTGH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: Y5695_CUPMC
Sequence: MIRRRLIIAAAAATALAACASGISNAPAPAPQPATTGSHAPGKTEVLWLGQAATRITTPGGKVIVIDPWLTGNPKTPPAFKQLSALGKVDMILLTHAHGDHLGDAPAIATTQHVPIWNGGGMGPQLVSLGLVTSDLVQPFGKSGTVMPFGPNGPKITAVHAEHSSELVWKNPATNKNESHYGGEPVGYIIEMENGFKIWHMGDTGLFSDMKLIAERYKPDLAMIPIGGHYTMGPQDAAIAVRDFIKPRYAIPMHYGTSPMLRGTPDEFKAALGAGATTAVIVPDPGQQVAF
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Rmet_5695.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: RL4_PSYA2
Sequence: MDLKTVTGAAVELSDTAFGREFNEALVHQVVTAYLAGARQGTRAQKTRAEVSGGGIKPWRQKGTGRARAGSIRSPIWRGGGRAFAAKPQDWSQKVNRKMYRGAMQCILAELIRQERLILVEEISVSGPKTKELIAKLNELGAPRALIVTKEVDENLYLAARNIPHVNVLDTSEVDPVSLIAFDKVIMSVEAAKQFEEALA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: HFQ_YERE8
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNPSGSTNNYHGSNPSAPQQPQQDSDDAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: R35A3_ARATH
Sequence: MVKGRQGERVRLYVRGTILGYKRSKSNQYPNTSLVQIEGVNTQEEVNWYKGKRMAYIYKAKTKKNGSHYRCIWGKVTRPHGNSGVVRAKFTSNLPPKSMGSRVRVFMYPSNI
What are the official names of this protein?
60S ribosomal protein L35a-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL33 family.
Protein: CP11A_RABIT
Sequence: RGLPSRSVFLRGCQASLSTAQERLGHPGVPTREGVRVATRSPRPYHEIPSPGDNGWLNLYHLAEEKGTHRVHYRHVQNFQKYGPIYRENLGNVESVYIMDPEDVALLFNSEGPQPERFLIPPWVAYHEYYRRPVGVLLKKAQGWKRDRVALNQEVMAPDAIKNFVPLLEAVSQAFVRMLHGRVQQGVFSGDISDDLFRFAFESMTNIMFGERLGMLEETVDPEAHEFIDAVYQMFHTSVPMLSLPPSLFRLFRTRTWRDHVAAWDVIFTNADKYTQSFYWDLRQKQDLGGSYRGILYSLLGTSKLSFEDIKANVTEMLAGSVDTTSMTLQWHLYEMGAALGMQEMLRAEVLAARRQAQGDMTAMLQSVPLLKASIKETLRLHPISVTLQRYLVNDLVLQDYMIPAKTLVQVANYGMGREPSFFANPEKFDPPRWLDKDKNATHFR
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones.  Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule.  Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
What are the official names of this protein?
Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450(scc).
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: TRPC_STRZJ
Sequence: MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDCLQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREISSQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLVETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTGQDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: HIS1_BURMS
Sequence: MSAPLTLALSKGRIFEETVPLLAAAGVTVAEDPETSRKLILPTTDPNLRVIVVRATDVPTYVEYGAADFGVAGKDVLLEHGGGGLYQPIDLNIARCRMSVAVPAGFDYANAVRQGARLRVATKYVETAREHFAAKGVHVDLIKLYGSMELAPLVGLADAIVDLVSSGGTLKANNLVEVEEIMPISSRLVVNQAALKLKRAALKPFLDAFERASLGSGA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIF9_ORYSI
Sequence: MSTRAPVELDFLGLRAAAADADDRHAKSGGSSASSSSSIRGMETSAIARIGPHLLRRVIAAARPPPPPSTAPVPEEMPGAAAAAAPMTLFYNGSVAVFDVSHDKAEAIMRMATEATKAKGLARGNAIVGNFAKEPLTRTKSLQRFLSKRKERLTSLGPYQVGGPAAVGATTSTTTKSFLAKEEEHTAS
What is the function of this protein?
Repressor of jasmonate responses.
What are the official names of this protein?
Protein TIFY 9.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
Protein: RUVC_JANMA
Sequence: MKILGIDPGLRTTGFGVIEKHGNKLTYIASGTIKTPDADLPQRLKTILSSVSEVIATYHPDCAAIEKVFVNVNPQSTLLLGQARGAAICALVHADLLVAEYTALQVKQAVVGQGKAQKAQVQDMVQRLLKLSGLPGTDAADALGVAICHAHSGEALSVLGALAPELARKGLRVRGGRLVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TERT_CANLF
Sequence: MPRAPRCRAVRALLRGRYREVLPLATFLRRLGPPGRLLVRRGDPAAFRALVAQCLVCVPWGARPPPAAPCFRQVSCLKELVARVVQRLCERGARNVLAFGFALLDGARGGPPVAFTTSVRSYLPNTVTETLRGSGAWGLLLRRVGDDVLTHLLARCALYLLVAPSCAYQVCGPPLYDLCAPASLPLPAPGLPGLPGLPGLGAGAGASADLRPTRQAQNSGARRRRGSPGSGVPLAKRPRRSVASEPERGAHRSFPRAQQPPVSEAPAVTPAVAASPAASWEGGPPGTRPTTPAWHPYPGPQGVPHDPAHPETKRFLYCSGGRERLRPSFLLSALPPTLSGARKLVETIFLGSAPQKPGAARRMRRLPARYWRMRPLFQELLGNHARCPYRALLRTHCPLRAMAAKEGSGNQAHRGVGICPLERPVAAPQEQTDSTRLVQLLRQHSSPWQVYAFLRACLCWLVPTGLWGSRHNQRRFLRNVKKFISLGKHAKLSLQELTWKMKVRDCTWLHGNPGACCVPAAEHRRREEILARFLVLVDGHIYVVKLLRSFFYVTETTFQKNRLFFYRKSVWSQLQSIGIRQLFNSVHLRELSEAEVRRHREARPALLTSRLRFLPKPSGLRPIVNMDYIMGARTFHRDKKVQHLTSQLKTLFSVLNYERARRPSLLGASMLGMDDIHRAWRTFVLRIRAQNPAPQLYFVKVDVTGAYDALPQDRLVEVIANVIRPQESTYCVRHYAVVQRTARGHVRKAFKRHVSTFADLQPYMRQFVERLQETSLLRDAVVIEQSSSLNEAGSSLFHLFLRLVHNHVVRIGGKSYIQCQGVPQGSILSTLLCSLCYGDMERRLFPGIEQDGVLLRLVDDFLLVTPHLTQAQAFLRTLVKGVPEYGCRANLQKTAVNFPVEDGALGSAAPLQLPAHCLFPWCGLLLDTRTLEVSCDYSSYAHTSIRASLTFSQGAKPGRNMRRKLLAVLRLKCCALFLDLQVNGIHTVYMNVYKIFLLQAYRFHACVLQLPFNQPVRKNPSFFLRVIADTASCCYSLLKARNAGLSLGAKGASGLFPSEAARWLCLHAFLLKLAHHSGTYRCLLGALQAAKAHLSRQLPRGTLAALEAAADPSLTADFKTILD
What is the function of this protein?
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes.  Active in progenitor and cancer cells.  Inactive, or very low activity, in normal somatic cells.  Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.  Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'.  The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension.  More active on substrates containing 2 or 3 telomeric repeats.  Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers.  Modulates Wnt signaling.  Plays important roles in aging and antiapoptosis (By similarity).
What are the official names of this protein?
Telomerase reverse transcriptase, Telomerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the reverse transcriptase family. Telomerase subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus. Chromosome, telomere. Cytoplasm. Nucleus, PML body. Note=Shuttling between nuclear and cytoplasm depends on cell cycle, phosphorylation states, transformation and DNA damage. Diffuse localization in the nucleoplasm. Enriched in nucleoli of certain cell types. Translocated to the cytoplasm via nuclear pores in a CRM1/RAN-dependent manner involving oxidative stress-mediated phosphorylation at Tyr-697. Dephosphorylation at this site by SHP2 retains TERT in the nucleus. Translocated to the nucleus by phosphorylation by AKT (By similarity).
Protein: IRAP_SHIFL
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPCQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_PARMW
Sequence: MPVWVASAARAALRALLGHPFEPNQQVVQPDGGEPLLVPVRSAARLSDDQALAISRCDPGPGLDLTRDLEIWVRVAWTPSADQGLVLMPGEGVGRIGAGGDACLSTYARQLLECTLLPLLPPGQGLEVEPVLPRGRSLAERTSNAAFGVVDGLALIGTQAEVQQSAAPEQLEQVLRELRALVADPGFGGSVALVIGENGLDLARRAGLSPLLKVGNWLGPVLVAAAEAGVKDLLLLGYHGKLIKLAGGIFHTHHHLADGRLEVLTALGLDVGLSLEELRHLRAAASVEDAFQRLNPETAMDLGRLLAATVEQRSQAYIARYGDWSLRIAAVLFDRSRTLRWRGPMAEERFFTLQD
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: TTCA_VIBCM
Sequence: MTAQTQELTKAQQYNFNKLQKRIRRNTGQAIADFNMIEDGDRIMVCLSGGKDSFTMLDILMSLQKSAPISFELVAVNLDQKQPGFPEHVLPEYLESLGVEYKIVEEDTYAIVQDKVPEGKTTCALCSRLRRGILYRTAKELGATKIALGHHRDDILETLFLNMFYGGKMKGMPPKLVSDNGEHVVIRPLAYCREKDIIKYSDMRGYPIIPCNLCGSQPNLQRQAVKQMLNDWDKRFPGRIETMFRAMQNVVPSHLADFSLFDFKSIDKNSGVINGGDIGFDKEEIAPQVVEDEDLVMEFDPSLQLNVTNI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_STAAN
Sequence: MTMTDPIADMLTRVRNANMVRHEKLELPASNIKKEIAEILKSEGFIKNVEYVEDDKQGVLRLFLKYGQNDERVITGLKRISKPGLRVYAKASEMPKVLNGLGIALVSTSEGVITDKEARKRNVGGEIIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NPTXR_RAT
Sequence: MKFLAVLLAAGMLAFLGAVICIIASVPLAASPARALPGGTDNASAASAAGAPGPQRSLSALQGAGGSAGPSVLPGEPAASVFPPPPGPLLSRFLCTPLAAACPSGAEQGDAAGERAELLLLQSTAEQLRQTALQQEARIRADRDTIRELTGKLGRCESGLPRGLQDAGPRRDTMADGAWDSPALLVELENAVRALRDRIERIEQELPARGNLSSSAPAPAVPTALHSKMDELEGQLLAKVLALEKERAALSHGSHQQRQEVEKELDALQGRVAELEHGSSAYSPPDAFKVSIPIRNNYMYARVRKAVPELYAFTACMWLRSRSGGSGQGTPFSYSVPGQANEIVLLEAGLEPMELLINDKVAQLPLSLKDSNWHHICIAWTTRDGLWSAYQDGELRGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTGPLMGNVLPWEDKLVEAFGGAKKAAFDVCKRRAKA
What is the function of this protein?
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
What are the official names of this protein?
Neuronal pentraxin receptor.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: HRCA_STRMU
Sequence: MITQRQKDILNLIVELFTKTHEPIGSKTLQNSIASSSATIRNDMAALEKLGLLEKAHTSSGRLPSQEGFRYFVEHSLNPDSLDEQDVYQVIKAFDFEAFRLGDLLQRASDVLANLTGYTALILDVEPKKQRLTTFDIVKLSNHDALAVLTLDEASPVTVQFAIPKNFLDSDLMTVAKIARERFLNQTVLDIHYRLRTELPQIIQKYFPRTDNVLDLFDHIFNPIFQEEVFISGKIKTLEFAGLNTYQFLENLQSVALEIRQSLPEDELHRVQVADSKEKSLADLTVISQKFLIPYRGFGILTVIGPVDLDYQRTISLINVISRVLAVKLGDFYRYLNSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: NAC77_ORYSJ
Sequence: MVESTTSLVKLEQDGGLFLPPGFRFHPTDAEVILSYLLQKLLNPSFTSLPIGEVDLNKCEPWDLPSKAKMGEKEWYFFSHKDMKYPTGMRTNRATKEGYWKATGKDREIFRQPAAVNTSSYGGSSNKKKQLVGMKKTLVFYMGRAPKGTKTNWVMHEFRLHANLHNHHPNLRLNPKDEWVVCKVFHKKQGDEAINNQQQQPQYAAVDQYSAETPNSGSSVVQAGDIDGGDDFFQLDDIIDPSIYFVSNSSNILSAPPNNNNAVYSVSASTTTTNTTAVSFQQQPNYYSLINKSSSSSSSNYSAPLQQHVSSWNITPGAGGAHGIGSSYYNLQQQQAAMVKALENVIAVPNFGTLLPSSNKLKGLSKSAMAGLTQQNPLGVPQYKIENYGDHYISRQ
What is the function of this protein?
Probable transcription factor involved in stress response (By similarity).  Binds to DNA-specific sequences of CLPD1 and OAT promoters in vitro (PubMed:18813954).
What are the official names of this protein?
NAC domain-containing protein 77, ONAC077, NAC domain-containing protein 300, ONAC300.
What are the subcellular locations of this protein?
Nucleus.
Protein: YI004_HUMAN
Sequence: MQCWQQPFLRFLQQPFFLATASLAGSSSSFNVLIPKRDEDGDGEGPGDVTAGVSRAAGSPSGWEAPWVQQPRCCRRATPVCCAGQGPPRSLQQGGSEVLLGQLCSPEPDWLPSSGPKVAKQVFQVAAELLQHPEHFVPSSVPEGCVHKPGSTCDGSLKGRAYPSCVPKRDPEHSREESHPLSG
What are the official names of this protein?
Putative uncharacterized protein UNQ6494/PRO21346.
What are the subcellular locations of this protein?
Secreted.
Protein: RR4_HUPLU
Sequence: MSRYRGPRLKIIRRLGELPGLTRKTPKLKPDYINKSTPNKKVSQYCIRLEEKQKLRFHHGLAEQQLLKYVRIARRAKGSTGQVLLQLLEMRLDNIIFRLGMAPTIPGARQLVNHKHILVNNRAINVPSYRCKPKDIITTRDRPESRARITKNYEFSQTYKIPNHLTLHSLQSVGLVNKIVDRESIDLNINELLVVEYYSRKA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YIDD_STAAN
Sequence: MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HPPD_XENTR
Sequence: MTSYTDKGEKHARGRFLSFHHLTFWVGNAKQAASFYCDKFGFEPCAYKGLETGSRDVVSHAIKQDKIIFVFQSPLNPGNQEMGQHMIKHGDGVKDVAFQVEDCDFLFQKAKDHGAVVVREPWIEEDEGGKVKYAVLQTYGDTTHTLLEYLGPYRGVFLPGYKEPLFRDPLLPTLPSGCLSFIDHIVGNQPDNEMVPIVEWYQKCLLFHRFWSVDDKQIHTEYSSLRSIVVTNYEETIKMPINEPAAGKKKSQIQEYVDYYGSAGVQHIALNTSNIIKAVKNLKSRGIEFLSAPDTYYEELRKKLKTAKITVKEDLNVLQELKILVDYDDKGYLLQIFTKPMQDRPTLFLEVIQRYNHFGFGAGNFKSLFEAIETDQDARGNLTIYAANGEHQVL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
What are the official names of this protein?
4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvic acid oxidase, 4HPPD, HPD, HPPDase.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: NS1_I80A8
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPPLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: NAGB_LIGS1
Sequence: MKIIKVKDQVEGGKEALKVFKEALDSGVKVFGLATGSTPETTYDELVKSDIDFSNSISVNLDEYVGLKPEDEQSYAYFMKEHLFNAKPFAKSFLPNGMAEDADQECERYDKLLEEYHVGLQLLGIGRNGHIGFNEPGSSFDGKTHKVALTQSTINANSRFFDNEEDVPKYAYSMGIGTIMKSDTILLEAFGKNKAEAVKAMIEGPVTPEVPASVLQNHPDVVVIIDEEAASLLK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ACCA_ECO57
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.