PharMolix/UniProtQA huggingface dataset:
Protein: MLTG_HAEIN
Sequence: MKKFLIAILLLILILAGVASFSYYKMTEFVKTPVNVQADELLTIERGTTSSKLATLFEQEKLIADGKLLPYLLKLKPELNKIKAGTYSLENVKTVQDLLDLLNSGKEVQFNVKWIEGKTFKDWRKDLENAPHLVQTLKDKSNEEIFALLDLPDIGQNLELKNVEGWLYPDTYNYTPKSTDLELLKRSAERMKKALNKAWNERDEDLPLANPYEMLILASIVEKETGIANERAKVASVFINRLKAKMKLQTDPTVIYGMGENYNGNIRKKDLETKTPYNTYVIDGLPPTPIAMPSESSLQAVANPEKTDFYYFVADGSGGHKFTRNLNEHNKAVQEYLRWYRSQKNAK
What is the function of this protein?
Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
What are the official names of this protein?
Endolytic murein transglycosylase, Peptidoglycan polymerization terminase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase MltG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GATB_CAMFF
Sequence: MFETVIGLEVHCQLNTKTKIFCSCSTSFGDEPNTHVCPTCLALPGALPVLNKEAVKKAISFGKAINATVNKKSVFDRKNYFYPDLPKAYQISQFTIPIVEKGELFIKVGGEIKRIGITRAHLEEDAGKNNHETNKSLVDLNRAGTPLLEIVSEPDLRNSDEAVAYLKKLHSILRFLNISDANMQEGSFRCDVNVSIRPKGDEKLYTRVEIKNLNSFKFIQKAIEYEVERQILSWEDGKYDEEVYQETRLFDTNKLVTKSMRSKEDSAEYRYFPDPDLLPVIIPDKMMEEASVLPELPDEKKARYVKDLGIKESDAEVIISSYEMARYFEDLIEAKNSPKLAVTWLCVELLGRLKNGVTIETSPVDSKKLSNLINRIEDGTISQKAAKDVLDYVMEHDEDVSSVIEKLGLKQVSDDSAILAIIDSVLSANSDKVAEFKSGKDKLFGFFVGQVMKEGKGAFNPSKVNDLLKSKL
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: COAA_BACVZ
Sequence: MKSKELNLHTLYTQHSRESWAGFGGHLSIAVSEEEAKAVEGLNDYLSVEEVETIYIPLVRLLHLHVTSAARRNQHVNVFLKHPHSAKIPFIIGIAGSVAVGKSTTARILQKLLSRLPDRPKVSLVTTDGFLYPTAELKRKNLLSRKGFPESYDVKALLEFLNDIKSGKERVEAPVYSHLTYDREEGAVEVVEGADIVIIEGINVLQSPTLEDDREDPRIFVSDFFDFSIYVDAEESRIFTWYLERFRLLRETAFQDPASYFHKFKDLSDAEADTMAASIWESVNRPNLYENILPTKFRSDLILRKGDGHKVEEVLVRRV
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC2_CRYNB
Sequence: MSTAAKRRLIRDFKRLTSDAPIGISGSPNPDNIMVWNAVIFGPPETPFEDGSFRLTLTFTDAYPNKPPTVRFISKMFHPNIYANGELCLDILQNRWSPTYDVAAILTSVQSLLNDPNPASPANVDAAQLFKENLKEYERRVKKTVELSWVDNADEIEAEVVEADEGSSS
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1.  H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.  Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 2, E2 ubiquitin-conjugating enzyme 2, Ubiquitin carrier protein UBC2, Ubiquitin-protein ligase UBC2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CULP7_MYCTU
Sequence: MAPGSHLVLAASEDCSSTHCVSQVGAKSLGVYAVNYPASNDFASSDFPKTVIDGIRDAGSHIQSMAMSCPQTRQVLGGYSQGAAVAGYVTSAVVPPAVPVQAVPAPMAPEVANHVAAVTLFGAPSAQFLGQYGAPPIAIGPLYQPKTLQLCADGDSICGDGNSPVAHGLYAVNGMVGQGANFAASRL
What is the function of this protein?
May have a role in cell wall processes (PubMed:26177502).  Does not exhibit cutinase activity (PubMed:19225166).
What are the official names of this protein?
Probable carboxylesterase Culp7, Cutinase-like protein 7, Culp7.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Secreted, cell wall.
Protein: Y3736_SHEPW
Sequence: MLILVSPAKTLDFENPAATQSYSIPTLLGQSEQLIDVCRKLTPSDIASLMKVSDKIAGLNVARFSSWDSDFTPDNAKQAVFAFRGDVYTGLDADTLSEASLQKAQQQLRILSGLYGLLKPLDLMQAYRLEMGTRLSNARGTNLYQFWGDIITDEINQTTAAQGDEFIINLASNEYFKAVKHKQLTANLVTPVFKDKKNGQYKVISFFAKKARGMMVRYILDNNVESLDALIKFDSAGYYYSEAESTVTAPVFLREEQ
What are the official names of this protein?
UPF0246 protein swp_3736.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: DADA_ECOLC
Sequence: MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKFRFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: TIG_RICM5
Sequence: MGITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKKKYGTSVRNDIIERKINHSVNHVIKEHNLNIIGRPKIEELQNESDKALEFTVKIELLPKITIPDFKKISLDRPKLEVNSKDVEEQLEKLAALTKNYTKESKAKIKAGDQVTIDAIGYIKEKAFKDGKLNDFKVIIGSNALIPGFEKQLIGSKTGSEIDVNVTFPENYHAKDLAGKDARFVVQIKAVHTAEPTVIDDEFAKKFQSNSLEELRTHFTKQIENESEEAINTIMKMNLFDKLEKLLDFDVPESLLEQEKNILKSGTDKNEQDESLLKDKSSKEITAYYNKLALRRVRIGLLLAEYAKSKNLQLEPDDLRKVIMQQARNFPGQENMIFDFYKNNPRAIEGLKGPALEDKAVQYIFNHEIKLKEKKYTKEELEKYLEAEEQRITLI
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EFTU2_HALHL
Sequence: MSKEKFERKKPHINVGTIGHVDHGKTTLTAALTKVLAEAHGGDARAFDQIDNAPEERARGITIATAHVEYESESRHYAHVDCPGHADYVKNMITGAAQMDGSILVVSAADGPMPQTREHILLARQVGVPAIVVFLNKADMVDDAELLELVEMEVRELLSDYDFDGDNIPVVTGSALKALEGDDSEMGRPAIIKLVEAMDAHIPQPERPVDGDFLMPIEDVFSISGRGTVVTGRVERGVIKVGEEVEIVGITDTRKTTCTGVEMFRKLLDQGEAGDNIGALLRGIKRDDVERGQVLCKPKSITPHTHFEAEVYVLSKDEGGRHTPFFNGYRPQFYFRTTDVTGTVTLPEGTEMVMPGDNVKMTVQLIAPIAMEDGLRFAIREGGRTVGAGVVSKILD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA1_AILME
Sequence: MAASQVPGEINIQAGETAKSGDRDLLGNDCRDQDRLPQRSWRQKCASYVLALRPWSFSASLTPVALGSALAYRSQGVLDPRLLVGCAVAVLAVHGAGNLVNTYYDFSKGIDHKKSDDRTLVDRILEPQDVVLFGVFLYTLGCVCAACLYCLSPLKLEHLALIYFGGLSGSFLYTGGIGFKYVALGDLVILITFGPLAVMFAYAVQVGSLAVFPLVYAIPLALSTEAVLHSNNTRDMESDREAGIVTLAILIGPTLSYVLYNTLLFLPYLIFSILATHCSISLALPLLTVPMAFSLERQFRSQTFNKLPQRTAKLNLLLGLFYVFGIILAPAGSLPKL
What is the function of this protein?
Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10.  MK-4 is a vitamin K2 isoform required for endothelial cell development.  Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4.  Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme: coenzyme Q10, also named ubiquinone, plays an important antioxidant role in the cardiovascular system.  Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress.
What are the official names of this protein?
UbiA prenyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion.
Protein: DNAA_CHLAD
Sequence: MNLTHIWKTTLSALQSQTSRHDYEALLRPAMLLSLDNGIARIGVSSPIQKEGLENRLLMPLRNALTRVVGYPVQVQVLIANQALRPEVTAAPRNGTHVALEPEPFVTEPPTPAFTSGNGNGERAVQLDLASAMRSGMLNPRYTFASFIVGSSNRLAHAACLAVADNPGQAYNPLFLYGGVGLGKTHLLHAIGNRVLDRDPEINVLYVSSEKFTNDLINAIRRQQTEEFRMRYRNIDVLLIDDIQFIAGKDATQEEFFHTFNTLHSAAKHIVISSDRPPKAILTLEERLRSRFEWGLIVDVQPPDLETRTAILRAKAEQMSVHVPDEVIDFLAHKIQSNIRELEGSLNRVAAYAELNRLPITIDTATAALADLLGNQRRRRISAEAILQIVSEHYGIEVEQLRARNRSRHVVVPRQVAMYLLREETESSLVDIGNLLGGRDHTTVMYGCEKIAEEINTDSHLRSEVMAIRERIQMMRGL
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFA2_LACGA
Sequence: MSIEFKNVDYIYAPGTPFQTQGLTNISFKIRSGSFVAIAGHTGSGKSTLMQHFDGLLLPSKGSVTIADKSITSNTSSKSLKEIRKKVGLVFQFPESQLFEETVLKDVMFGPLNFGFSEQKAKEQAIQWIRKVGLSEQVMNKSPFELSGGQMRRVAIAGVMAYEPDILCLDEPAAGLDPEGQKQMFDIFKNYQREGHTVILISHNMDDISQYADDMLVLEHGHLIKHASPKEVFSDPDWLKKHFLDEPATSKFARKLEKGGFQFSEMPLTVDSLVNEITTKLKSKGGNE
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: STS1_ASPFC
Sequence: MNSLVATPPVPPHFYEYSRLSSPHPMSTPTHTPINRKRKADDDGNDHDGRMSASPTNSPAFTPRSLPAPRSFKRSRPNVSGRPLSLPRLLETLDTDALRGILRSMCERHPALADEVIHTSPRPSVSSALQVLRNYQSTLQNSFPLGGNPESDYAYNRVRQPLGNLLDALSDFTPHFLPPHETQASVSLSYLDGATDIIHALPRWHSPQNNIERDSAYDEICKAWILVIREAAKRGGGIQLQYGGWDQKLAKHNQNAGGRLQAAVNELGNSLGWMHGPDSQGYGSSTGGDLVSVREQLLSGTYGLGTPVKVGPW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome sts1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPOZ_JANMA
Sequence: MARITIEDCLKQIPNRFQLTLSATYRARQLLQGHTPKVDAKDKPTVIALREIAAGHVGIEMLKKVPS
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ILVC_SOLUE
Sequence: MPNRYYEKDGNLDFLAGRTVAIIGYGSQGHAHALNLRDSGVDVVVGLPAGSKSTAKAEAAGLKVLSPADAAKTANVVMILVPDHIQADLYNNEIAPHMTAGKTLMFAHGFNIHFGQIKPPVDIDVTMVAPKAPGHRVRELYTEGVGVPALVAVHQNATGQALERALAYALALGCLKAGVIDTNFREETESDLFGEQAVLCGGAAELVRAGFQTLVDAGYAPEIAYFECLHELKLIVDLIQEGGLSYMRYSVSDTAEYGDYTRGPRVVNDQTRAEMKKILSEIQSGEFARQWIEENKTGRKNFLAMREKGHNDQIEVVGRELREMMTFLKKKKEVGVPVA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: HIS6_CHLSY
Sequence: MLTRRIIPCLDVKAGRVVKGVKFLNHRDAGDPVELAAAYNAAGADELVFYDITASSDERAIMVEVVERTAAEVFIPLTVGGGLRSVDDMYRMLRAGADKVSLNTAAVYNPQLIAEGARRFGSQCIVLSVDAKRVNAPGEPPRWEVFTHTGANPRPTGLDAIEWIKRGIDLGAGEICINSMDADGARTGYDLELLQAITAISPVPVIASGGVGSPHDMYRGIVEGGADAVLAASIFHFGDYSVADVKRYLAERGVAVRMI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEX1_XENLA
Sequence: MEKRPYSVEWLSESSQRKAVYSNADLLGYKSGNPDKESNISLPSRATGPTLPSVDYREKENYCVRNVQNEERSPPVKDQLHSQPAPQELDTSRRALMVVPACERSTDQGNKVTGTTDTNKKAKPVCDEDAAARARTKFSPEQLEELERSFKENRYIGSSEKRRLSKVLKLSETQIKTWFQNRRMKFKRQTQDARVDAFFSGLYVPYYGYPDLPTPGYSVQPEFSVLAPHTMAAPSLPFGPLQSTVISPGLHPTAIPSANLGSYPYSSMLVHPMLNEPKRQRYSPY
What is the function of this protein?
Transcriptional repressor.  Acts in a ventral signaling pathway downstream of bmp4 to antagonize the Spemann organizer and ventrally pattern the embryonic mesoderm.  Represses transcription of the dorsal genes gsc and otx2.
What are the official names of this protein?
Homeobox protein vex1, Homeodomain transcription factor vex-1, Ventral homeobox protein, Xvex-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: METK_NITEU
Sequence: MSNYLFTSESVSEGHPDKVADQISDAILDAILQQDPHARVACETMCSTGLIVLSGEITTDATIDYNAIPRGIVREIGYTSSEIGFDASTCAVLTAFNKQSPDIAQGVNRSKDEEMDQGAGDQGLMFGYACDETPQLMPLPIYYAHRLVEQQAKLRKSGRLSWLRPDAKSQVSVRYEDGFPKNIETIVISTQHSPDVPRDELVEGVIEEVIKPVLPAEMLSNHIQYLINPTGRFVVGGPMGDCGLTGRKIIVDTYGGTAHHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLARKCEVQVAYAIGVAKPVSLMVQTFGTGKIPDGKLAELIARHFDLRPRAIIHELDLLRPIYGKTAAYGHFGREEPSFTWEKTDMAEQLKADAGI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNS7_SCHPO
Sequence: MADYWKSIPKYYCKYCQIFVKDTPFARRSHEQTYKHQDAIKKVMDDIHRSNLLRQELEKNLSIPKSATATTASAVSSELASYEKPKKEHPKLRPSKKKATLDDWDIPTSSTETDTISTTHTSYIPTLLAKQEENEETKETTTNKNESLPGTSLKRNREIIEKEERSSFHFRVKPKNLDKVPKLAENEGNKSLESKESNENKVVFKKKKSGKLRTKSSLKEYDQS
What are the official names of this protein?
Uncharacterized protein C18H10.07.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MTNA_ENT38
Sequence: MQTLQTTSLRVADNQLFILDQQALPQEKRWLDASTVEALVGHIHALRVRGAPLIGLSASLLLALLAENGHSRDQLAVALDTLRASRPTAVNLMNNLDRMKQALWQEDFVPALVTEALRLIEEDKQLCDAIARAGSQLVKPGSRLLTHCNTGGLATAGVGTALGVIAHAFAAGNVNNVWVDETRPLLQGGRLTAWELGELGVPYQLITDSMAASLMAKGQVDAVWVGADRIAANGDVANKIGTYSLAVLAKFHGIPFYVAAPQTTLDPHCPNGEAIPIEQRDAREVTGVAGSFGAVQWAPENAQVYNPAFDVTPAALISGWVLDTGVVLPEAVEQGVFKSSAV
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: PDCD1_MOUSE
Sequence: MWVRQVPWSFTWAVLQLSWQSGWLLEVPNGPWRSLTFYPAWLTVSEGANATFTCSLSNWSEDLMLNWNRLSPSNQTEKQAAFCNGLSQPVQDARFQIIQLPNRHDFHMNILDTRRNDSGIYLCGAISLHPKAKIEESPGAELVVTERILETSTRYPSPSPKPEGRFQGMVIGIMSALVGIPVLLLLAWALAVFCSTSMSEARGAGSKDDTLKEEPSAAPVPSVAYEELDFQGREKTPELPTACVHTEYATIVFTEGLGASAMGRRGSADGLQGPRPPRHEDGHCSWPL
What is the function of this protein?
Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:10485649, PubMed:11698646, PubMed:11209085, PubMed:21300912).  Delivers inhibitory signals upon binding to ligands, such as CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:11015443, PubMed:11224527, PubMed:22641383, PubMed:18287011, PubMed:18641123).  Following T-cell receptor (TCR) engagement, PDCD1 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation (PubMed:22641383).  Suppresses T-cell activation through the recruitment of PTPN11/SHP-2: following ligand-binding, PDCD1 is phosphorylated within the ITSM motif, leading to the recruitment of the protein tyrosine phosphatase PTPN11/SHP-2 that mediates dephosphorylation of key TCR proximal signaling molecules, such as ZAP70, PRKCQ/PKCtheta and CD247/CD3zeta (PubMed:11698646, PubMed:22641383).  The PDCD1-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (By similarity).
What are the official names of this protein?
Programmed cell death protein 1, Protein PD-1, mPD-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TARF_STAA8
Sequence: MIKNTIKKLIEHSIYTTFKLLSKLPNKNLIYFESFHGKQYSDNPKALYEYLTEHSDAQLIWGVKKGYEHIFQQHNVPYVTKFSMKWFLAMPRAKAWMINTRTPDWLYKSPRTTYLQTWHGTPLKKIGLDISNVKMLGTNTQNYQDGFKKESQRWDYLVSPNPYSTSIFQNAFHVSRDKILETGYPRNDKLSHKRNDTEYINGIKTRLNIPLDKKVIMYAPTWRDDEAIREGSYQFNVNFDIEALRQALDDDYVILLRMHYLVVTRIDEHDDFVKDVSDYEDISDLYLISDALVTDYSSVMFDFGVLKRPQIFYAYDLDKYGDELRGFYMDYKKELPGPIVENQTALIDALKQIDETANEYIEARTVFYQKFCSLEDGQASQRICQTIFK
What is the function of this protein?
Catalyzes the addition of a second glycerol phosphate unit from CDP-glycerol to the prenolpyrophosphate-linked disaccharide, to complete the linkage unit.
What are the official names of this protein?
Teichoic acid glycerol-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-glycerol glycerophosphotransferase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL3_VIBC3
Sequence: MIGLIGRKVGMTRVFTEDGVSIPVTVVEVEANRVSQVKTLETDGYAAIQVTTGSKKANRVTKPEAGHFAKAGVEAGRGLWEFRLENGEEFAVGSELTVELFNEVKKVDVTGTSKGKGFQGAVKRWNFRTQDMTHGNSLSHRAPGSIGQCQTPGRVFKGKKMAGHMGAERVTTQNLEIVRVDAERNLLLIKGAVPGATGGNVIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TP1A_RANLT
Sequence: LGALTQLLLNLGKL
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Temporin-1LTa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
Protein: PP2C2_SCHPO
Sequence: MGQTLSEPVLDKHSSSGGDRWLHFGVSHMQGWRISMEDAHCALLNFTDSNSSNPPTSFFGVFDGHGGDRVAKYCRQHLPDIIKSQPSFWKGNYDEALKSGFLAADNALMQDRDMQEDPSGCTATTALIVDHQVIYCANAGDSRTVLGRKGTAEPLSFDHKPNNDVEKARITAAGGFIDFGRVNGSLALSRAIGDFEYKKDSSLPPEKQIVTAFPDVVIHNIDPDDEFLILACDGIWDCKSSQQVVEFVRRGIVARQSLEVICENLMDRCIASNSESCGIGCDNMTICIVAFLHGRGLEDWYNWITQRVNSGEGPCAPPSYAELRGPNTIADARNLQLEYDHIASHEYGSGDTYDSDSDDETIAYDRYYLH
What is the function of this protein?
Has an important role in osmotic stability and cell shape control.  It may negatively regulate the osmosensing signal transmitted through wis1 map kinase.
What are the official names of this protein?
Protein phosphatase 2C homolog 2, PP2C-2.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: ERFL1_ARATH
Sequence: MVSLRRRRLLGLCCGPNGYVTPLPFLTAEEMITGIPNPNARAAYNPGPAETVTTVIVEKKAIEERSRRTRSKHMHFRSDYSDISPVNSDSISPKYQPPKRRKQHRRKRVHNQEPCLMRGVYYKNMKWQAAIKVEKKQIHLGTFSSQEEAARLYDRAAFMCGREPNFELSEEVIRELKQQSWEEFLNCTRRTITNKKPKSRIEHEDTKINASMPHQPEEEEQDSDKM
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor-like protein At4g13040.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RHGC_ASPFN
Sequence: MQVKLFYTLALWAPILVSAQLSGSVGPLVDFKTKAKNKTCDITDYGAVADGKTDVGPAILDAWGNCSTGGLIYVPPGTYSLATDLELKHGESTAFQLDGVLARGHEGSYQLILVRNCHDCEFFSGNSQGAVQGYGYEYLQDGNYGERLFRFQDVSDFSVHGFAAIDSPAYYLVFDTVSNGEIYNLLVRGIADLGMTDAFDIWGQNVWIHDIEVTNGDECVTVKSPASDFLIENIYCNLSGGTAIGSLGTGTNISNIHYRNLYMNQADACYLKTHNGDGIVKNIVWENVIVHGGPYPLAVNEAWGKDVGSTGVQVQNLTFRNWYGENTANSRPAIRIECDEDVPCYDITLDNVNLWTEDGDYVEWSCANAYGSGACLQEAKDTGDLATYTTAVTVTATPSYSATHMPGDFTTNPPSTAPFTIPPMPTSFYPGATPISTLLSLSGAGGL
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).
What are the official names of this protein?
Probable rhamnogalacturonase C, RGase C, RHG C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.