PharMolix/UniProtQA huggingface dataset:
Protein: CNIH2_CHICK
Sequence: MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYCIHGLFCLMFLCAAEWVTLGLNLPLLLYHLWRYFHRPSDGSEGLFDAVSIMDADILGYCQKEAWCKLAFYLLSFFYYLYSMVYTLVSF
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs) (By similarity).  Plays an important role in the proper development of cranial nerves by facilitating the secretion of HBEGF.
What are the official names of this protein?
Protein cornichon homolog 2, CNIH-2, Cornichon family AMPA receptor auxiliary protein 2, Cornichon-like protein.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MED19_CHAGB
Sequence: MSCHPQTPQSPSQFSPNTSDLMMSMTGSVTSTTTTLPTPAHSVNGSSIPSELTQDTAMGDDSPHKRKRDGDDMGSRAQKKVHVEDRKLGIDDLHMDVGEKYLLCRTPHPRPRPHVSEDLFEMYGLTGLAIEVARVRPNGEKNALRKTYKGHIKRLGVQGHFDEDKQDPNREYSLSHLMKLPQDVWDLQHVRGQDIRDGFTNEVQQKLSRAMTMGRGVVPRDQWDSSVLGEMGPGKGERQALSARPTAPNTPLPSAGPQGLPRPKTGTPLMQDASRSMRTIKKRSYGDSSFEGYGESYDDGADTGYSTGEGDMSSGQKRRKKVLIND
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VATD_CLOB1
Sequence: MKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEGSFKDFLMASAVMSPEFLEEAVAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLMADEIEKTRRRVNALEYMTIPQLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: RL2_STRA3
Sequence: MGIKVYKPTTNGRRNMTSLDFAEITTNTPEKSLLVSLKNKAGRNNNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKAYILAPKGLEVGQRIISGPEADIKVGNALPLANIPVGTVIHNIELQPGKGAELIRAAGASAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRNRWKGVRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNQK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: UVRC_ALIB4
Sequence: MNLQEKLQQLPNDAGVYQYFDKNGHLLYIGKAKILKNRVKSYFKFTPKLQPADKLSPRIYKMISEVESCEWIVVPNEHDALILENSLIKQLKPKYNILLRDDKTYPYIFVDFDEDFPRLDITRRIQKSKSIKYFGPYSTGARDMLDSIYEIVPLVQKKSCVKGKKACLFYQIQKCLAPCENKISKEEYAKIVENALEYIYNKTKLISKLNEKMLQYSNDFRFEEAMTLRDRIKTIEKSQIKSDIDLATNEDIDIFAINANNKKAVIVRMFLRDGKLTSSSHDFLKIDNFDEEFEFDYQEAYERAIINYYDNEIPLLPKEILIAHELEITNELEEFLHTRFNKKIKLINPKKDKKREIVNIALNNCDELLRIENSKNQTSIYEELKELFNLQTLPYLIESFDNSHMMGQATVGAMIVWNESLNTFDKKAFRHYNLESKDEYSQMKEMLIRRIESFEKNPAPDLWIIDGGETLLKLAFDIVQSVGVNLDIIAIAKEKIDAKAHRAKGKAKDIIHYKTKNGEFKSFNLLTSDKRLQFVQRQRDEAHRFAITFHKKQKRAQDKQISLLQIKGIGEAKIKKLLLYFGEFEKIKKASFDELKTVLNEKDASTILDYFTNFKD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPGS_RUBXD
Sequence: MRTLFLIDGEHYPPVVLDAMRRVREQLGAKGVAAAFLGGTEKIGEGADYGLPLVAAEDPVSAVRQALERYGVEAVVDLSDEPVVGYRERMRIASLALAAGARYVGSDFELRPPEMRRVPGKPSLAVIGTGKRVGKTAVTGYLARLLDREGFRPAVVSMGRGGPPEPEVLEGRRLEVGSDYLLRALERGAHAASDYYETAALSRVTTVGCRRCGGGLAGEPFVSNVLEGARIAAGLDTGITVFDGSGAAIPPVEVDRRVLVAGAHQDPEYVAGYLGAYRLLISDLLVLTMAEEPMAPPGRVEELVRRVREVRPDLPVIPAVFRPRPVGEVRGMRVAYVSTAPPAVLKRLAGHLEEGYGCEVVAVSGNLSNRSKLAEDLEGMPGVDAYLTEIKAAAVDVVTRRGAEEGRRVIYCDNDPVAEGLDGALLRLARAAGRGRSGDRGV
What is the function of this protein?
Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
What are the official names of this protein?
Cyclic 2,3-diphosphoglycerate synthetase, cDPGS.
What is the protein family that this protein belongs to?
Belongs to the cyclic 2,3-diphosphoglycerate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRKP1_PITHY
Sequence: MSILKKSLFLVLFLGLVSFSICEEEKREAEEEENEDEIEEESDEKKRESPDRPPGFSPFRIY
What is the function of this protein?
Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle (By similarity).  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
Phyllokininogen-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Bradykinin-related peptide subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UGTP_BACC4
Sequence: MIKNPKVLILTAHYGNGHVQVAKTLEQTFRQKGIEDVIVCDLFGESHPFITDITKYLYLKSYTIGKELYRLFYYGVEKIYDKKIASWYANFGRKRLKTLLQVEKPDIVINTFPIIAVPELKKQTGISIPVYNVLTDFCVHKIWIHREVDRYFVATDHVKELMVDIGVPAEQIVETGIPIRSSFELKVNPEIIYTKYQLCKNKKILLIVAGAHGVLGNVKELCQSFMSVPNLQIVVVCGKNEALKQDLLSLQKQNSDALKVFGYVENIDELFRVTSCMITKPGGITLSEAAALQVPVILYKPVPGQENENAMYFERKGAAVVIRDDSEVFAKTEALLQDDVKLLQMKEAMKSIYLPEPAGHIVDAILAENHAEPRHIPIKSPALAQSFT
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GNRHR_BOVIN
Sequence: MANSDSPEQNENHCSAINSSIPLTPGSLPTLTLSGKIRVTVTFFLFLLSTIFNTSFLLKLQNWTQRKEKRKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITKPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGMIHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMVICNAKIIFTLTRVLHQDPHKLQLNQSKNNIPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPDMVNRVSDPVNHFFFLFAFLNPCFDPLIYGYFSL
What is the function of this protein?
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH).  This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECA_HELPJ
Sequence: MAIDEDKQKAISLAIKQIDKVFGKGALVRLGDKQVEKIDAISTGSLGLDLALGIGGVPKGRIIEIYGPESSGKTTLSLHIIAECQKNGGVCAFIDAEHALDVYYAKRLGVDTENLLVSQPSTGEEALEILETITRSGGIDLVVVDSVAALTPKAEIDGDMGDQHVGLQARLMSHALRKITGVLHKMNTTLIFINQIRMKIGMTGYGSPETTTGGNALKFYASVRIDIRRIAALKQNEQHIGNRAKAKVVKNKVAPPFREAEFDIMFGEGISKEGEIIDYGVKLDIVDKSGAWLSYQDKKLGQGRENAKALLKEDKALADEITLKIKESIGSNEEIMPLPDEPLEEME
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAB2_CANGA
Sequence: MDNKPLITVAEASEYKELLALEKLPQSSQLSYKAIFKSVSSEWEQVKTDITHVNENILKDINEEIEQTDQIEKKLKSSFKSINQHYHKLLKHRRNRQNDEGTSDLFLKYKNDVNELASNIETIENGLDMVIQNMISFDSTSSLDGDSLFNSSIITKRHYPLLYDLIHKNYNKGQNSDKTSKDNSKITTDVTLPASDEDNSPDIEEQQSKLSSLSFSIEKAQNPIPVDKAKNTDNSSRSIINSNVKIKNPTLILPMIKQRAQPSVALDAKPVIARDSYKADTKSIIAPEIT
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit VAB2, BLOC-1 subunit VAB2.
What is the protein family that this protein belongs to?
Belongs to the VAB2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Vacuole. Cytoplasm.
Protein: CHS6_SORBI
Sequence: MAGATVTVEEVRKAQRATGPATVLAIGTATPANCVHQADYPDYYFRITKSEHMTELKEKFKRMCDKSQIRKRYMHLTEEYLAENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSMVGQALFGDGAAAVIVGADPDERVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERSLEEAFKPLGITDYNSIFWVAHPGGPAILDQVEAKVGLKKERMRATRHVLSEYGNMSSACVLFILDEMRKRSAEDGQATTGEGFDWGVLFGFGPGLTVETVVLHSVPITTGATITA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 6, Naringenin-chalcone synthase 6.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RL11_DESAL
Sequence: MAKKVLAMVKLQVQAGKANPSPPIGPALGQHGVNIMEFCKAFNARTADQEGMVIPVVLTVYQDRSFSFITKTPPASVLILKAAKLAKGSSDPKKIKVGKITKAQVEDIANLKMVDLNAKDMAGASKIIAGTARSMGIEVV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MDH_BARBK
Sequence: MKRKKIALIGSGMIGGTLAHMIGLKELGDIVLFDVAEGLPQGKALDIAESSPVDGFDINLTGANAYEAIEGADVIIVTAGVARKPGMSRDDLLGINLKVMEQVGAGIKKYAPSAFVICITNPLDAMVWALQKFSGLPAQKVVGMAGVLDSARFRYFLSQEFNISIKDITAFVLGGHGDSMVPLVRYSTVSGIPLPDLVKMGWTTHEKIDQIVQRTRDGGAEIVSLLKTGSAFYAPASSAVAMAEAYLKDTRRVLPVAARLSGEYGIKDMYVGVPVVIGAGGVERVIEIDLNDNEKSAFEKSVNAVKELCKTCSALAPNLKE
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: RS10_STRPS
Sequence: MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CYB_MYOOY
Sequence: MTNIRKSXPLMKIINSSFIDLPAPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGIYYGSYMYTETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVKWIWGGFSVDKATLTRFFAFHFLLPFVISAMVMVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGLLLMITVLLMLVLFSPDMLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIIIPLLHTSKQRSMTFRPLSQCLFWLLVADLFTLTWIGGQPVEHPYVIIGQLASILYFSIIXILMPXISFAENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TPM1_CIOIN
Sequence: MEAIKKKMTMLKLDKENAIDRAEQAETDKKSAEDKATGLEEELQGLQKRLKATEDELDTSQEKLRTAIENLENAEKKAADAEQEVASLNRRITLVEEELDRAQERLTISLSKLEEAEKAADESERGRKVIENRSLKDEERLEVQEIQLTEAKNIAEDADRKYVEVARKLVMVEAELERGEERAELAESKAIELEEELKIVANNLKSLEASAEKYAAKEGIFEEEIKTLSDKLKDSETRAEFAEKSVVKLEKNIDELEDSLYAEKCKIKAISEDMDVTLQGIGDL
What is the function of this protein?
The function of tropomyosin in smooth muscle and non-muscle cells is not clear.
What are the official names of this protein?
Tropomyosin, smooth muscle/fibroblast CTM1.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: TRPD_PSE14
Sequence: MNIKSALNRVVNQLDLTTDEMRDVMREIMTGQCTEAQIGAFLMGMRMKSETIDEIVGAVSVMRELASSVELKTLDGVVDIVGTGGDGANIFNVSTASAFVIAAAGCKVAKHGNRAVSGKSGSADLLEAAGVYLNLTPVQVARCIDSVGIGFMFAQSHHTAMKHTAGPRRELGLRTLFNMLGPLTNPAGVRHQIVGVFNQALCRPLAEVLLRLGSKHVLVVHSQDGLDEFSLAAPTFVAELKNGEVTEYWVQPEDLGIKSQSLYGLAVESPAVSLELIRDALGRRKTENGQKAAEMIVLNAGAALYAADHATSLKEGVALAHDALHTGLAREKLEELGAFTAVFKQENEA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: AQP2_AMBHO
Sequence: SIAFSRAVFSEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLAIGTLVQTLGHISGAHINPAVTVACLVGCHVSFLRATFYVAAQLLGAVAGAALLHELTPPDIRG
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
What are the official names of this protein?
Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, AQP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
Protein: Y1818_COXBU
Sequence: MSRLPSKTKYHSSHRSLNRKTPLLQRSSETNSLRESGIETASSQLSLAASSYTPIDEEMTELELKIYLFLFTRALNHKLGYTQENNPDDKAQKAGIDINLDCLNYLLEILYQNLEPQLEKGANLSYHKSSTARKALEYHETLNSRLKKKIAKDAEHKNPLTLLRILNTKTTSISTLIGTGGGIGITGAGAIAGSAAAGIGTAVTVGVLLFYLCWRTTSEYWKKKNAEKLFEHTDQIDNENIIELVSALSAFYIVKEFEHKNMQKASLKLSLNPESLFEIFQNIYHNKSFRLPSQLPIQKELKAIAKQAKIDADKIHTHLIEYVNTNKAQSISINLYALIIPSFAYNSEESPTVVKTVAALHAWLWALDKTLDMKDFLFRNSFEKRLEKVRAGVVKTMKTFKEEVNNVLLETDDSSSGVSLLADEDKTDRVKEWVNKQKLPSPGALSPIKSASHLALFSSLREQKDKAVNSSGSRLSLRLGN
What are the official names of this protein?
Uncharacterized protein CBU_1818.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HEMA_I85A1
Sequence: QDLPGNDYSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGRDCTLIDALLGDPHCDVFQDETWDLFVERSNAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPNSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTNLYVQASGGVTVSTRRSQQTIIPNIGSRPWVRGQSGRISIYWTVVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNADVLVALENQHTIDLTDSEMNKLFERTRRQLRENAEDMGNGCFKIYHKCDNVCIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: SMTA_CHLAA
Sequence: MAKASRLTRSTGQPTEVSEGQVTGTSEMPPTGEEPSGHAESKPPASDPMSTPGTGQEQLPLSGIRVIDVGNFLAGPYAASILGEFGAEVLKIEHPLGGDPMRRFGTATARHDATLAWLSEARNRKSVTIDLRQQEGVALFLKLVAKSDILIENFRPGTMEEWGLSWPVLQATNPGLIMLRVSGYGQTGPYRRRSGFAHIAHAFSGLSYLAGFPGETPVLPGTAPLGDYIASLFGAIGILIALRHKEQTGRGQLIDVGIYEAVFRILDEIAPAYGLFGKIREREGAGSFIAVPHGHFRSKDGKWVAIACTTDKMFERLAEAMERPELASPELYGDQRKRLAARDIVNQITIEWVGSLTRDEVMRRCLEKEVPVGPLNSIADMFNDEHFLARGNFACIEAEGIGEVVVPNVIPRLSETPGRVTNLGPPLGNATYEVLRELLDISAEEIKRLRSRKII
What is the function of this protein?
Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation.  Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity).
What are the official names of this protein?
Succinyl-CoA--L-malate CoA-transferase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: NUSB_BLOFL
Sequence: MKSITRRFARLCALQALYAWQLSKNDYTMISNYVIKIQNIQNFNISYFLTLYIGVIHTIKELNTLMIPYLSRGLKAIDYIEYSVLLIALFELTQCCDVPYKVVINEAIELAKIFGSEKSHKFINGVLDKIITEKLYKG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MGN1_ORYSJ
Sequence: MATVAGDDGGGGGEFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKKDTMIRKEVFVSPSVLREATRIIHESEIMKEDDSNWPEPDRVGRQELEIVMGNEHISFTTSKIGSLVDVQTSKDPEGLRIFYYLVQDLKCFVFSLINLHFKIKPIQS
What is the function of this protein?
Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD).  The MAGO-Y14 heterodimer inhibits the ATPase activity of EIF4A3, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation.  The MAGO-Y14 heterodimer interacts with the EJC key regulator PYM leading to EJC disassembly in the cytoplasm (By similarity).  EJC core heterodimers play essential roles in plant growth and development, and pollen and seed development (PubMed:25230811, PubMed:24820023).  The MAGO-Y14 heterodimer selectively binds to the UDT1 (UNDEVELOPED TAPETUM 1) pre-mRNA transcript and regulates the splicing of UDT1, a key regulator in stamen development (PubMed:24820023).
What are the official names of this protein?
Protein mago nashi homolog 1, OsMAGO1, Mago nashi-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the mago nashi family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA.
Protein: GUAA_VIBPA
Sequence: MTKNIHDQRILILDFGSQYTQLVARRVREIGVYCELWSWDVEEADIREFNPDGIILSGGPESVTEENSPRAPQYVFDSGVPVLGVCYGMQTMAEQLGGKVAGSNEREFGYAQVKVSGESAIFKDLEATQDVWMSHGDKVVEIPADFVKVGETDTCPYAAMANEEKKYYGVQFHPEVTHTKGGLQMLENFVLGVCGCERLWTSESIIEDAVARIKEQVGDDEVILGLSGGVDSSVVAMLVHRAIGDKLTCVFVDNGLLRLNEGQQVMDMFGDKFGLNIIKVDAEERFLEALKGKSDPEEKRKTIGHVFVDVFDEESKKLKNAKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEIKKEYCDLLRRADAIFIEELHAADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGKVSNRIINEVEGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL34_STRPZ
Sequence: MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.