PharMolix/UniProtQA huggingface dataset:
Protein: DNRF_STRPE
Sequence: MALTKPDVDVLVVGGGLGGLSTALFLARRGARVLLVERHASTSVLPKAAGQNPRTMELFRFGGVADEILATDDIRGAQGDFTIKVVERVGGRVLHSFAESFEELVGATEQCTPMPWALAPQDRVEPVLVAHAAKHGAEIRFATELTSFQAGDDGVTARLRDLGTGAESTVSARYLVAADGPRSAIRESLGITRHGHGTLAHFMGVIFEADLTAVVPPGSTGWYYLQHPDFTGTFGPTDRPNRHTFYVATTPERGERPEDYTPQRCTELIRLAVDAPGLVPDILDIQAWDMAAYIADRWREGPVLLVGDAAKVTPPTGGMGGNTAIGDGFDVAWKLAAVLRGEAGERLLDSYGAERSLVSRLVVDESLAIYAQRMAPHLLGSVPEERGTAQVVLGFRYRSTAVAAEDDDPEPTEDPRRPSGRPGFRAPHVWIEQDGTRRSTVELFGDCWVLLAAPEGGAWPGRPPAPPRIWASASTSISSAAMSPPPPAN
What is the function of this protein?
Involved in the biosynthesis of the anthracyclines carminomycin, rhodomycin and daunorubicin (daunomycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.  Catalyzes the incorporation of a hydroxyl group at position C-11 of aklavinone, resulting in epsilon-rhodomycinone.  It cannot accept substrates glycosylated at position C-7.  It can also hydroxylate 11-deoxycarminomycinone and can use both NAD or NADP.
What are the official names of this protein?
Aklavinone 12-hydroxylase DnrF, Aklavinone 11-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
Protein: RS11_GEOSW
Sequence: MARKTNTRKRRVRKNIETGIAHIRSTFNNTIVTITDVHGNTIAWSSAGALGFKGSRKSTPFAAQMAAEAAAKASMEHGMKTVEVNVKGPGAGREAAIRALQAAGLEITAIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CYB52_SCHPO
Sequence: MAEKTITVEEVLKHNTRDDLYIVVKDKVYDISKFLDAHPGGEEVLVDLAGRDASGPFEDVGHSEDAQELLEKFYIGNLLRTEDGPQLPTTGAAAGGSGYDSSQPVKPAMWLFVLVMVVAYFAFRKYVLK
What is the function of this protein?
Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
What are the official names of this protein?
Probable cytochrome b5 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side. Mitochondrion.
Protein: NSUN4_BOVIN
Sequence: MAALVVRGVRDMLKRADFATVPRRQRHKKKWASTEPKFPATRLALQNFDMTYSVQFGDLWPSIRVSLLSEQKYGALVNNFAAGDRVSAELEQLKARDFVNEAVFHREPEPENSQTAAPSPASWACSPNLRCFTFTRGDVSRFPPARLGSLGLMDYYLMDAASLLPVLALGLQPGDTVLDLCAAPGGKTLALLQTGCCRNLAANDLSTSRTSRLQRVLHSYVPQDVRDKNRVRVTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLHEEENSIFQRSRKKERQMLPVLQVQLLAAGLLATKPGGHIVYSTCSLSHLQNEYVVQGAIELLDNQYSIKVQVEDLTHFRKLFMNTFSFFPSCQVGELVIPNLMANFGPMYFCKMCRMT
What is the function of this protein?
Involved in mitochondrial ribosome assembly.  5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU).  Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled.  In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4 (By similarity).
What are the official names of this protein?
5-methylcytosine rRNA methyltransferase NSUN4, 5-methylcytosine tRNA methyltransferase NSUN4, NOL1/NOP2/Sun domain family member 4.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PEBP_PLAFA
Sequence: MTIPTISELKKDRIIPHVFPNDKIDLNVDLFISFKAGKEVNHGNVLDIAGTGSVPRNIKFSEEPPDGYCFVLFMVDPDYPSRLRPDGKEYIHWVVSGIKTKELIKGTQKNCVTILPYVGPSIKKGTGLHRISFIISLIKEEDKDNITGLPHYKGEKYITRVKFNNYESVHNIAQINNMKIVGYNWCQIEG
What are the official names of this protein?
Putative phosphatidylethanolamine-binding protein.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
Protein: PSB6_TOBAC
Sequence: MENTDVDQPHSMGTTIIGVTYNGGVVLGADSRTSTGMYVANRASDKITQLTDNVYVCRSGSAADSQIVSDYVRYFLHQHTIQLGQPATVKVAANLTRLLSYNNKDRLQTGMIIGGWDKYEGGKIYGIPPGGTVLEQPFAIGGSGSSYLYGFFDQAWKEGMTQEEAEKLVVTAVSLAIARDGASGGVVRTVTINKDGATRKFYSGDSLQLWHEELEPVNSLLDVVFASSPVPMVS
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit beta type-6, Proteasome delta chain, Tobacco cryptogein-induced protein 7, tcI 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SODC_SOLCS
Sequence: MVKAVAVLSSSEGVSGTIFFSQEAEGAPTTVTGDLSGLKPGPHGFHVHALGDTTNGCMSTGPHYNPHGKDHGAPDDEHRHAGDLGNVTVGEDGTAKFTIVDKQIPLIGAQSIIGRAVVVHADPDDLGKGGHELSKTTGNAGGRVACGIIGLQG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THN_PHOLT
Sequence: KSCCPTTTARNIYNTCRFGGGSRPVCAKLSGCKIISGTKCDSGWNH
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Phoratoxin.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL19_WOLTR
Sequence: MTNLLKKFNEQQMQVLAKEVPEFRPGDDLKVTFKVVDSTSERIQIFEGVCISKRNRGLHSSFAVRKVSHGESIVSQFFIYSPALVSVQVTRRGKVRRAKLYYLCKLFGKAARIKERATYKNNKSN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: CH60_CHLFF
Sequence: MAAKNIKYNEDARKKIHKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEIELEDKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYSEGLRNVTAGANPMDLKRGIDKAVKVVVDEIKKISKPVQHHKEIAQVATISANNDAEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDVVEGMNFNRGYLSSYFTTNPETQECVLEESLVLIYDKKISGIKDFLPVLQQVAESGRPLLIIAEDIEGEALATLVVNRLRAGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLISEELGMKLENTTLSMLGKAKKVIVSKEDTTIVEGLGNKEDIEARCENIKKQIEDSTSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATLAAVEEGILPGGGTALVRCIPTLEAFIPILTNEDEQIGARIVLKALSAPLKQIAANAGKEGAIICQQVLARSSNEGYDALRDAYTDMIEAGILDPTKVTRCALESAASVAGLLLTTEALIADIPEDKSSSAPAMPGAGMDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_ECO24
Sequence: MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: RK20_SOLTU
Sequence: MTRIKRGYIARRRRTKIRLFASSFRGAHSRLTRTITQQKIRALVSAHRDRDRKKRDFRRLWITRINAVIRERGVSYSYSRLIHDLYKRQLLLNRKILAQIAISNRNCLYMISNEIIKEVDWKESTRII
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ERA_SALEP
Sequence: MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: SWC4_CANAL
Sequence: MSANDILDVLNIQRDESNQPPKKKQKSSSTPTLPDGKQLTGMARELYNLVGPNTPPINLNSNSYTANKEKMKKFKPSPWTRMPFTPKQGIELNHWVKGSKELIEQQEFEEDGTPKPYFFEKYNVQLEIPEFVDEDTYDLYMIEIKEYESKMKEERARREKERKEREKRDLEEKKKKQQQQQQKSQQNPQNQIKDDEKNQDTRNNTDKKDSEQKSEDKPTVEAKKETDEKKDDVVLKDNTNETKPVTETTKSETETTEQNNSEKTNENETNKTNDKDGEGNLTKSKDSATEDQSNNKKENDEDTESEWTYKETKHLFELCQAFELKWPIIHDRFPNPNRTAEDLKEQFYRICIKILENQKNKNQALIDSLKAYCKPRELERKQYLENLLKRTPAEIAEEESLVIEARRFEIAAKKMLMERSNLLTLLDSPQTTQNVSQYQSSQGITNLYNNLLIYDKHQKKKQMANKSNPQQEPVPPPIPLAASSSVKRDRGFQTQLQQYLSSFLKQNHHTNPAVKQEINSIQQLLMKRLTQKEEEAYGLYFHGTEKLNPGVMLRSQQKLPGLNQRQSILKSVNILLQEMDIPTGGGTSWKPIMPTRKTMAKYDELIRSVVTLLDVKKAKDKLESEIKLIKSQRGL
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
SWR1-complex protein 4.
What is the protein family that this protein belongs to?
Belongs to the SWC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL271_ARATH
Sequence: MVKCMKPGKAVILLQGRYTGKKAVIVKSFDDGTVEKKYGHCLVAGLKKYPSKVIRKDSAKKTAKKSRVKCFFKVINYQHVMPTRYTLDLDLKNVVSADAISSKDKKVTALKEAKAKFEERFKTGKNRWFFTKLRF
What are the official names of this protein?
60S ribosomal protein L27-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL27 family.
Protein: NPLP2_DROME
Sequence: MAKLAICILVFALFALALSARVPREESNPAQEFLTKAQGDFNEFIEKLKALDAKKVEGLFKDGLNTVQEGLQKLNETFLQAPAAST
What are the official names of this protein?
Neuropeptide-like 2, NEF peptide.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1995_CITK8
Sequence: MKYELTATEARVIGCLLEKQVTTPEQYPLSVNGVVTASNQKTNREPVMNLSEHEVQEQLDNLVKRHFLRTVSGFGNRVTKYEQRFCNSEFGNLKLSPAEVALIATLLLRGAQTPGELRSRASRMYEFSDMAEVESTLEQLAARDDGPYVVRLAREPGKRESRYMHLFCGEVDEPVSSDDAPQAASGDLHARVEALEGEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein CKO_01995.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: SYC_MESHJ
Sequence: MTMNLINKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEKAQELGISEAELTEKYTNEYFKILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSKNDFVLWKKTQKGLFFKSLFGLGRPGWHTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFVNLNGKKMAKSLNNVLLAKNFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKICFEWYFDKKNEKTEKVEQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMRLDPESQEKIKNWNKLIMDKNYSEADKIREELWKIFKNS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHB_VIBHA
Sequence: MLKHSLIAASVITTLAGCSSLQSSEQQVVNSLADNLDIQYEVLTNHGANEGLACQDMGAEWASCNKVNMTLVNQGEAVDSKDWAIYFHSIRLILDVDNEQFKISRVTGDLHKLEPTDKFDGFAAGEEVVLPLVGEYWQLFETDFMPGAFVSAPNAEPKMIASLNTEDVASFVTGLEGNNLKRTPDDNNVFANAVSRFEKNEDLATQDVSTTLLPTPMHVEAGKGKVDIADGIALPKDAFDATQFAAIQDRAEVVGVDVRGDLPVSITVVPADFTGELAKSGAYEMSIKGDGIVIKAFDQAGAFYAVQSIFGLVDSQNADSLPQLSIKDAPRFDYRGVMVDVARNFHSKDAILATLDQMAAYKMNKLHLHLTDDEGWRLEIPGLPELTEVGANRCFDTQEKSCLLPQLGSGPTTDNFGSGYFSKADYVEILKYAKARNIEVIPEIDMPAHARAAVVSMEARYDRLMEEGKEAEANEYRLMDPQDTSNVTTVQFYNKQSFINPCMESSTRFVDKVISEVAAMHQEAGAPLTTWHFGGDEAKNIKLGAGFQDVNAEDKVSWKGTIDLSKQDKPFAQSPQCQTLITDGTVSDFAHLPSHFAEEVSKIVAEKGIPNFQAWQDGLKYSDGEKAFATENTRVNFWDVLYWGGTSSVYEWSKKGYDVIVSNPDYVYMDMPYEVDPKERGYYWATRATDTRKMFGFAPENMPQNAETSVDRDGNGFTGKGEIEAKPFYGLSAQLWSETVRNDEQYEYMVFPRVLAAAQRAWHRADWENDYKVGVEYSQNSNLVDKASLNQDYNRFANVLGQRELAKLEKSGIDYRLPVPGAKVEDGKLAMNVQFPGVTLQYSLDGENWLTYADNARPNVTGEVFIRSVSATGEKVSRITSVK
What is the function of this protein?
Hydrolysis of terminal, non-reducing N-acetyl-beta-D-glucosamine residues in chitobiose and higher analogs, and in glycoproteins.
What are the official names of this protein?
N,N'-diacetylchitobiase, Chitobiase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ATL_STAAM
Sequence: MAKKFNYKLPSMVALTLVGSAVTAHQVQAAETTQDQTTNKNVLDSNKVKATTEQAKAEVKNPTQNISGTQVYQDPAIVQPKTANNKTGNAQVSQKVDTAQVNGDTRANQSATTNNTQPVAKSTSTTAPKTNTNVTNAGYSLVDDEDDNSEHQINPELIKSAAKPAALETQYKAAAPKAKTEATPKVTTFSASAQPRSVAATPKTSLPKYKPQVNSSINDYIRKNNLKAPKIEEDYTSYFPKYAYRNGVGRPEGIVVHDTANDRSTINGEISYMKNNYQNAFVHAFVDGDRIIETAPTDYLSWGVGAVGNPRFINVEIVHTHDYASFARSMNNYADYAATQLQYYGLKPDSAEYDGNGTVWTHYAVSKYLGGTDHADPHGYLRSHNYSYDQLYDLINEKYLIKMGKVAPWGTQFTTTPTTPSKPTTPSKPSTGKLTVAANNGVAQIKPTNSGLYTTVYDKTGKATNEVQKTFAVSKTATLGNQKFYLVQDYNSGNKFGWVKEGDVVYNTAKSPVNVNQSYSIKSGTKLYTVPWGTSKQVAGSVSGSGNQTFKASKQQQIDKSIYLYGSVNGKSGWVSKAYLVDTAKPTPTPIPKPSTPTTNNKLTVSSLNGVAQINAKNNGLFTTVYDKTGKPTKEVQKTFAVTKEASLGGNKFYLVKDYNSPTLIGWVKQGDVIYNNAKSPVNVMQTYTVKPGTKLYSVPWGTYKQEAGAVSGTGNQTFKATKQQQIDKSIYLFGTVNGKSGWVSKAYLAVPAAPKKAVAQPKTAVKAYTVTKPQTTQTVSKIAQVKPNNTGIRASVYEKTAKNGAKYADRTFYVTKERAHGNETYVLLNNTSHNIPLGWFNVKDLNVQNLGKEVKTTQKYTVNKSNNGLSMVPWGTKNQVILTGNNIAQGTFNATKQVSVGKDVYLYGTINNRTGWVNAKDLTAPTAVKPTTSAAKDYNYTYVIKNGNGYYYVTPNSDTAKYSLKAFNEQPFAVVKEQVINGQTWYYGKLSNGKLAWIKSTDLAKELIKYNQTGMTLNQVAQIQAGLQYKPQVQRVPGKWTDANFNDVKHAMDTKRLAQDPALKYQFLRLDQPQNISIDKINQFLKGKGVLENQGAAFNKAAQMYGINEVYLISHALLETGNGTSQLAKGADVVNNKVVTNSNTKYHNVFGIAAYDNDPLREGIKYAKQAGWDTVSKAIVGGAKFIGNSYVKAGQNTLYKMRWNPAHPGTHQYATDVDWANINAKIIKGYYDKIGEVGKYFDIPQYK
What is the function of this protein?
Endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure.  One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.  Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells.  Acts as an autolysin in penicillin-induced lysis (By similarity).
What are the official names of this protein?
Bifunctional autolysin.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted, and then anchored on the cell surface at the peripheral cell wall above the completed septum (septal region), for the next cell division cycle.
Protein: VP7_ROTPB
Sequence: MYGIEYTTVLFYLISFVFVSYILKTITKIMDYIIYRITFIIVVLSILSNAQNYGINLPITGSMDTTYANSTQNDNFLSSTLCLYYPTEARTQINDNEWKDTLSQLFLTKGWPTGSVYFNEYSNVLEFSIDPKLYCDYNVVLIKFVSGEELDISELADLILNEWLCNPMDITLYYYQQTGEANKWISMGSSCTVKVCPLNTQTLGIGCQTTNVNTFETVADSEKLAIVDVVDSVNHKLDVTSTTCMIRNCNKLGPRENVAIIQVGGSNILDITADPTTSPQTERMMRVNWKKWWQVFYTVVDYINQIVQVMSKRSRSLDSSSFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: MRAY_RICCN
Sequence: MLYNLLLPHIHNSHIANLFHYITFRSALAIIITLSLSFITGPILIEFLRSLQKNGQPIRSDGPESHQTKVGTPTMGGIMIILSSCLSTLLLADLTNKYIWITLFGFISFGIIGFMDDYAKVTKDNHYGVRGKSKLLLQGIISFIICVLLEYLDKSPSHLLNVPFFKNLSLDLGYCYIVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTAGSFALISYLVGNLIYSNYLQLTYIPNTGELTVLCAGLVGSCLGFLWFNAQPAEVFMGDTGSLSLGGVLGIISVITKHEIVLAIVGGLFVIETASVILQVYYFKATKGKRIFKMAPLHHHFEKHGWAESKVVIRFWIISVIFALIGLSSLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TEG1_VZVD
Sequence: MFSRFARSFSSDDRTRKSYDGSYQSFNAGERDLPTPTRDWCSISQRITSERVRDGCLIPTPGEALETAVKALSEKTDSLTSPVLQSTERHSVLLGLHHNNVPESLVVSCMSNDVHDGFMQRYMETIQRCLDDLKLSGDGLWWVYENTYWQYLKYTTGAEVPVTSEKVNKKSKSTVLLFSSVVANKPISRHPFKSKVINSDYRGICQELREALGAVQKYMYFMRPDDPTNPSPDTRIRVQEIAAYTATGYGWMLWFLDVVDARVCRHLKLQFRRIRGPRASVIPDDLLRRHLKTGPAVSAGTGVAFILAATTASALTALLRISVLWRKEEWRDGLNGTAAAIVAAVELITLLHHHFQYLINMMLIGYACWGDGGLNDPYILKALRAQGRFLYFAGQLVRTMSTHSWVVLETSTHMWFSRAVAQSILAHGGKPTKYYAQVLAASKRYTPLHLRRISEPSSVSDQPYIRFNRLGSPIGTGIGNLECVCLTGNYLSDDVNASSHVINTEAPLNSIAPDTNRQRTSRVLVRPDTGLDVTVRKNHCLDIGHTDGSPVDPTYPDHYTRIKAEYEGPVRDESNTMFDQRSDLRHIETQASLNDHVYENIPPKEVGFNSSSDLDVDSLNGYTSGDMHTDDDLSPDFIPNDVPVRCKTTVTFRKNTPKSHH
What is the function of this protein?
Abundant tegument protein.  Trans-activates the immediate early genes (By similarity).
What are the official names of this protein?
Tegument protein UL46 homolog, Tegument protein VP11/12 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HHV-1 VP11/12 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host membrane; Multi-pass membrane protein.
Protein: TPIS1_LISIN
Sequence: MRKPIIAGNWKMNKTAAKAGQFAEDVKNNVPSSDAVESVVAAPALFLQELVRLTEGTNLRVAAQNCYFEDEGAFTGEISPFALADLGVSYVIIGHSERREYFHETDEDINKKAHAIFKHGMTPIICCGETLDQREAGQTDTWVRGQIRAALAGLTEEQVIKSVIAYEPIWAIGTGKSSTSADANETCAVIRAEVADAVSQKAADAVRIQYGGSVKPENIADYLAESDIDGALVGGASLEPASFLALLEAVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase 1, TIM 1, TPI 1, Triose-phosphate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPK1_DEBHA
Sequence: MEIYKITTPGEWTYFAKGNANILFKYTGSNDYLRHKLLRVRLLKEDEQYISTCELYDFIELKCKPLFPHQIIDIQLVVLTTDFVNQLNNEGNKLMVKERYGLLLPNILDGDYCKQFLSRNCQLYIGTDTTVQEAGVNRNTVPEKLQGQEQKKLQKQEQFNNDIDSVIFEIKPKWLYDNISSNYCRTCSLNQLRGFQRHFCPLDLLYEETIDQGLDDILSLIPQDLLIEISETNKIPVKQLFRIFLNNPNNVFQKLKEYQRINNKNDLIKNITSIYDVSQNLSLVMTLRDVGLFIKFEKYNKYNNIHNSHNNINNLINIEGYGKFLLTCNIYDLDLKSKLKYKHWLDTEEKLQSIYNSSNPDWRHCVKVHDNTNNLGT
What is the function of this protein?
Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
What are the official names of this protein?
Inositol-pentakisphosphate 2-kinase, Inositol-1,3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase, InsP5 2-kinase.
What is the protein family that this protein belongs to?
Belongs to the IPK1 type 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUS1_YARLI
Sequence: MTDQVRSDVQEKLVQSGEYEKLSQHIQARLRNSGWYDKVSALAQEEASKQDKVELSSLLEKVQPQACDLVDDDIKVETLKMIASFLEGALK
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body.