PharMolix/UniProtQA huggingface dataset:
Protein: NDK_STAAC
Sequence: MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIRGDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1061_METJA
Sequence: MFQDISNFYKDKTILVTGGTGSIGKEIVKTLLKFNPKTIRVLDINETALFELEHELNSEKIRCFIGDVRDKDRLKRAIEEVDVVFHAAALKHVPLCEYNPFEAVKTNVIGTQNLIEVAMDEEVEKFITISTDKAVNPVNVMGATKLLAERLTISANLYKGKRKTAFSVVRFGNVLNSRGSILPLLKEQIKKGGPVTLTHPDMTRFIMSINEAVKLVLKACYLAKGGEIFILKMPSVRIKDLIEVVIEELAPKYGYKPEDIEIKIIGKRPGEKLYEELIIEEEIYNLEELEDMFVVYPYGVDGNKNNKIIYNSKDAKFLNKEKIKKILKEISYL
What are the official names of this protein?
Uncharacterized membrane protein MJ1061.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family.
Protein: RL20_PROMM
Sequence: MARVKRGNVARKRRNKILRLARGFQGSNGSLFRTANQRVMKALCNAYRDRRRRKRDFRRLWIARINAAARINGVSYSRLIGGLKKADVRINRKMLAQLAVMDPKSFTSVVTSAKS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CF050_HUMAN
Sequence: MANTQLDHLHYTTEFTRNDLLIICKKFNLMLMDEDIISLLAIFIKMCLWLWKQFLKRGSKCSETSELLEKVKLQLAFTAYKYVDICFPEQMAYSRYIRWYIH
What are the official names of this protein?
Putative uncharacterized protein C6orf50, Nasopharyngeal carcinoma-associated gene 19 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YQGF_STRA5
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEESGNFGFDRLAELVKEYKVDKFVVGLPKNMNNTSGPRVEASQAYGDKITELFNLPVEYQDERLTTVQAERMLVEQADISRGKRKKVIDKLAAQLILQNYLDRMF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 143G1_DANRE
Sequence: MVDREQLVQKARLAEQAERYDDMAAAMKSVTELNEALSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELETVCQDVLNLLDNFLIKNCGETQHESKVFYLKMKGDYYRYLAEVATGEKRAAVVESSEKSYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDEGGEGNN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner (By similarity).
What are the official names of this protein?
14-3-3 protein gamma-1.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_STAAE
Sequence: MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDGASQSYVRSKKKAAEKIGMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVDGFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEGKNAVVIGRSHIVGQPVSKLLLQKNASVTILHSRSKDMASYLKDADVIVSAVGKPGLVTKDVVKEGAVIIDVGNTPDENGKLKGDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIDS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PURA_PORGI
Sequence: MEKVDVLLGLQWGDEGKGKIVDVLTPHYDIVARFQGGPNAGHTLEFNGEKYVLRSIPSGIFQGEKTNVIGNGVVLDPLLFKEEAEALARSGHDLTKRLVISRKAHLIMPTHRLLDAANEMAKGSGKIGTTGKGIGPTYTDKVSRNGLRVGDLEHGFEEAYSVAKERHLRILNSLNYPTDKLADLEERWMEATKYLRKFEFVDSEFLINGALLSGKKVLAEGAQGSLLDIDFGSYPFVTSSNTICAGCCTGLGVAPRNVGDVYGIFKAYCTRVGAGPFPTELFDETGDKLCELGREFGSVTGRKRRCGWIDLVALRYTIMLNGVTKLIMMKSDVMDLFPTIKACVAYEIDGKETRNFPFHLTEGVTPVYKELPGWQQSMTNVVSEADFPKEFSDYIAFLEKELGVGIAIVSVGPDREQTIIRQA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3C_SCHPO
Sequence: MSRFFKGGSSDSDAESVDSSEENRLTSSRLKKQDDSSSEEESSEEESASSSESESSEEESESEESEVEVPKKKAVAASEDSESDSESSEEEEETESEEDSEVSDESESESESESESEEESESEEESDESERSGPSSFLKKPEKEEAKPAGLKFLRGESSEESSDEEEGRRVVKSAKDKRYEEFISCMETIKNAMSSNNWIVVSNEFDHLNKVSQKCKEAGRNPPPYIEFLSALDQKLESADKAFIKSLDAANGRAFNALKQRVRKNNRQFQSDIDRYRKDPEGFMKPAELNEIPKPAGKAGQDEVIVDGVATRGIVAPTEGLGKPEEITPADIFKYLRAIFEARGKKSTDRSEQIRLLEKLSTIAVTDYQRLRVKVALLAVRFDINTGSGQYMPIDQWNAALTELHSILDIFDANPKIVIVEQVEDENEEEEEAIAAAENNNGVIQVQGSVVSFLERLDDEFTRSLQMIDPHTPEYIDRLKDETSLYTLLVRSQGYLERIGVVENTARLIMRRLDRVYYKPEQVIRANEEVAWRSFPPTFDLTITPRATTTTPDILIHSLCVYLYNNGVSLLRTRAMLCHIYHEALQNRFYKARDMLLMSHLQDSVHAADIATQILHNRTMVQIGLCAFRNGMVQETQYALQDISTTGRVKELLGQGIQAPKFGQFTPDQDRLDKQLVLPFHMHINLELLECVYLTCSMLMEIPAMAAASSTASDSRKRVISRPFRRMLEYIDRQLFVGPPENTREYIMQASKALADGEWRRCEEFIHAIKIWSLMPDADKIKQMLSEKIREEGLRTYLLAYAAFYDSVSLEFLATTFDLPVQRVTVIVSRLLSKREIHAALDQVHGAIIFERVEINKLESLTVSLSEKTAQLNEANEKLYEQKTQHTNPQENRRRDKGGSVKRRNERTENRNRSDMN
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIBCH_DANRE
Sequence: MSLIIFTSAQRLRSVCRLQRIHGHMMSSKAGSEVLFEKVGKAGVITLNRPKALNALTLNMIRHIYPQLKKWDKDSETDIVIIKGAGEKAFCAGGDIRAIAEAGKAGNLLSQVFFREEYILNNTIGTYQKPYVALINGITMGGGVGLSVHGQFRVATEKTLFAMPETGIGLFPDVGGGYFLPRLQGKLGLFLALTGFRLKGRDVQRVGVATHFVQSEKIESLEKDLVDLKSPSISDVAQLLDSYQEQSHLDAEKPFVLQEQTEAIDRLFSAGSVEEIVENLKKDGSAFALKQAETLAKMSPTSLKLTFRQIEEGARMSLQEVFMMEYRLSQACMNGHDFYEGVRAVLIDKDQSPKWKPSTLAGVSEQFVDKCFSSLDERDLKL
What is the function of this protein?
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite.  Has high activity toward isobutyryl-CoA.  Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.  Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity).
What are the official names of this protein?
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YIZB_BACSU
Sequence: MKTNQVNDRWIVQFRKGIFELAILSLLRSKPMYGYELTSSLKTTSALAISEGAIYPILKRMTEKGWIEFFWEDSLDGPKRKYYKMTQKGEEMLKERLEKYLETHQALLSLSGDLL
What are the official names of this protein?
Putative DNA-binding protein YizB.
Protein: TDCC_SALEP
Sequence: MSTTDSIVSSQAKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLQMPALNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLSNIALTGHDGILVTVWLGISIMVFSFNFSPIVSSFVVSKREEYEKEFGREFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPQNMADAKAQNIPVLSYLANHFASLSGTKSTFATVLEYGASIIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKTKVSMGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTLIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_PIG
Sequence: MTNIRKSHPLMKIINNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWVIRYLHANGASMFFICLFIHVGRGLYYGSYMFLETWNIGVVLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAAVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGALFMMLILLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVASILILILMPMLHTSKQRGMMFRPLSQCLFWMLVADLITLTWIGGQPVEHPFIIIGQLASILYFLIILVLMPITSIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RCORA_CAEEL
Sequence: MDSYTSSDEDASRKENISDEGLNMLNASPEPMEEDDPEEQAEQEEETSRMARPIRSMRKRETTSGESMGDEDEDLEDEEDEDEEAEAREHHESGAHDTSFSNPLSNVDNLIHVGTEYQAIIQPTAEQLEKEPCRDQQIWAFPDEMNENRLTEYISEATGRYQLPIDRALFILNKQSNDFDAAMVQAMRRKEIHDDWTAEEISLFSTCFFHFGKRFKKIHAAMPQRSLSSIIQYYYNTKKVQNYKTMINVHLNETDTYDELFKEVNHLERVPSGYCENCNAKSDLLILNRVMSRHECKPCILYFRLMRVPRPASLRALTKRRQRVLCPEYMKIYVYGYLELMEPANGKAIKRLGIGKEKEEDDDIMVVDDCLLRKPSGPYIVEQSIEADPIDENTCRMTRCFDTPAALALIDNIKRKHHMCVPLVWRVKQTKCMEENEILNEEARQQMFRATMTYSRVPKGEIANWKKDMMALKGRFERFTPELDTTATNGNRSGKVRINYGWSPEEKKNAIRCFHWYKDNFELIAELMATKTVEQIKKFYMDNEKLILESIDTYRAELKSKLGK
What is the function of this protein?
Probable corepressor protein acting as a component of a complex that represses transcription (Probable).  May play a role, as part of a CoREST-like complex, together with the chromobox protein homologs hpl-1 and hpl-2, in the formation of the vulva and in fertility (PubMed:26476455).
What are the official names of this protein?
REST corepressor rcor-1.
What is the protein family that this protein belongs to?
Belongs to the CoREST family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SAA_CANLF
Sequence: MKLFPGLLFCSLVLGVSGQWYSFVSEAAQGAWDMWRAYSDMREANYKNSDKYFHARGNYDAAQRGPGGAWAAKVISDARENSQRITDLLRFGDSGHGAEDSKADQAANEWGRSGKDPNHFRPAGLPDKY
What is the function of this protein?
Major acute phase reactant.  Apolipoprotein of the HDL complex.
What are the official names of this protein?
Serum amyloid A protein, SAA.
What is the protein family that this protein belongs to?
Belongs to the SAA family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRYGS_RABIT
Sequence: MSKTGTKITFYEDKNFQGRRYDCDCDCSDFHTYLSRCNSIRVEGGTWAVYERPDFAGYMYILPQGDYPEYQRWMGLNDRLSSCRALHLSSGGQYKIQIFEKGDFNGQMYETTEDCPSIMEQFHMREIHSCKVLDGAWIFYELPNYRGRQYLLDKKEYRKPVDWGAVSPAVQSFRRIVES
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin S, Beta-crystallin S, Gamma-S-crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: RS12_POLNA
Sequence: MPTINQLVRQGREVEKIKSKSPAMENSPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEIISYIGGEGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQSRSKYGAKRPKAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: LUXS_SHIDS
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: COTF_BACSU
Sequence: MDERRTLAWHETLEMHELVAFQSNGLIKLKKMIREVKDPQLRQLYNVSIQGVEQNLRELLPFFPQAPHREDEEEERADNPFYSGDLLGFAKTSVRSYAIAITETATPQLRNVLVKQLNAAIQLHAQVYRYMYQHGYYPSYNLSELLKNDVRNANRAISMK
What are the official names of this protein?
Spore coat protein F.
What is the protein family that this protein belongs to?
Belongs to the CotF family.
What are the subcellular locations of this protein?
Spore coat.
Protein: RL23_LEGPA
Sequence: MNAERLMMVLREPHTSEKATVMADKFKQFTFKVLKNATKTEIKLAVEHIFNVKVKSVSVVNVKGKSKRFKQTSGKRSDWKKAFVSLHADQDIDFTVTE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: TRAJ1_ECOLI
Sequence: MYPMDRIQQKHARQIDLLENLTAVIQDYPNPACIRDETGKFIFCNTLFHESFLTQDQSAEKWLLSQRDFCELISVTEMEAYRNEHTHLNLVEDVFIQNRFWTISVQSFLNGHRNIILWQFYDAAHVRHKDSYNQKTIVSDDIRNIIRRMSDDSSVSSYVNDVFYLYSTGISHNAIARILNISISTSKKHASLICDYFSVSNKDELIILLYNKKFIYYLYEKAMCIINTR
What is the function of this protein?
This protein is essential for positively regulating the expression of transfer genes that are involved in the conjugal transfer of DNA between bacterial cells.
What are the official names of this protein?
Protein TraJ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPT_HAEIG
Sequence: MISQIDKTELLERFLHYVSFHTQSKPHAKHSPSSVGQMKLAMQLQKELIQLGLENVEVSKYAVVTAFLPANDPNLTKTIGLVAHLDTSPQCSGKNVRPEVIEEYRGGDIALGIGEEFISPVYYSFMQKLVGQTLIVTDGTTLLGADNKAGIAEIMTALSILQKENIPHCNIRVAFTPDEEIGLGIHYFPMEKFSCDWAYTIDGGEVGELEYENFNAATAKVRFFGRNIHTGYAKGKMLNALTLACEFQQVFPVDEVPEKTDGKVGFYHLEDFSGDIEQVELTYLIRDFDEQNFAQRKAFIKNQVEKFNAKKGLKKPIELEIQDSYQNMYDVVKNVPQSIELADRAMKAVGIKPNHKPIRGGTDGAFLASKGLACPNIFTGGYNFHSKHELVSLQGMENTVQVIIEMLKCKDL
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IN21B_ORYSJ
Sequence: MAAAAAAPASSEKEVLPPSLTSSSEPPPLFDGTTRLYVAYHCPYAQRAWIARNYKGLQDKIKIVAIDLADRPAWYKEKVYPENKVPSLEHNNQVKGESLDLVKYIDTNFEGPALLPDDSEKQQFAEELLAYTDAFNKASYSSIVAKGDVCDEAVAALDKIEAALSKFNDGPFFLGQFSLVDIAYVPFIERFQIFFSGIKNYDITKGRPNLQKFIEEVNKIHAYTETKQDPQFLLEHTKKRLGIA
What are the official names of this protein?
Protein IN2-1 homolog B, Glutathione S-transferase GSTZ5.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. HSP26 family.
Protein: DXS_PARUW
Sequence: MTQSILSNLNHPNDIKNLSYSDLKYLAHEIRQRIIEVLSVNGGHLASNLGVVELTLALHKVFESPDDKFIWDVSHQTYVHKLLTGRNDRFHEIRQFKGLCGFSHPKESIHDHFHAGHAGTALSLALGVAKNRDLTKRKDYIIPIIGDATLTCGLTLEALNNISRELKRFIVILNDNAMSISKNVGAITHILSRLLSNPTTNKIHQELDTIVSKIPNYGPILSQQGHKITESLKNLVSPAVYFEQYGLSYIGPIDGHDTKKLVDVLEGVKDSNWPVIIHVLTRKGEGMDEAIKNPISYHGAKPFSKDTGKFLPNPVTKPTFPKIFGSHLLKMAEKDPSIVAITPAMSAGSCLDDFMKTFPERCIDVGIAESHAITFAGGMAYGGKMKIVASIYATFLQRAFDNVFHDICLQELPVVFAIDRAGISGPDGSTHHGIYDISFLNAMPNMIIAQPRNGQVLKELMESAFSWKRPTAIRYPNLMTEEFNHPICERELGKGEVLIEGTEILIVALGHMNQAALKVRDLLAQTGIEATVLDPIFVKPLDSELFCKLLLNHNKIVTIEEHSVVSGMGSIINNFLVGQGFNQIQVLNLGIPEAFLDHGRNQDLLNEIGLVPEKIFRQIQSHFNLIAQNTLNPVA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: GLO2_FRATW
Sequence: MQIKRWFLNNSLRNYQYLLYDKSHAIVIDPLKSDIFAEFIAKNKLQLEAILITHKHGDHIAGVKKLLAIYLNAKVYAYTGNDLFKPDIYVKDGSFINLGFTSFRVMYIPGHIDDHVCFLFEQERALFCGDTLFNAGVGGVQAESADINQLYDSLVKITKLDGDIKPYPAHDYWLGNLDFALSILADDSYFNYYRNQVAELAAEDKPIVNLAEEAKLNIFIRAMSDKALLKALPDYSLGREMFVKLRQLKNNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: HPRT_CANLF
Sequence: MATRSLGVVISDDEPGYDLDLFCIPHHYAEDLEKVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDGSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVKEHNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_CYAP4
Sequence: MTTDLQAELETEVERRRNFAIISHPDAGKTTLTEKLLLYGGAIHEAGAVKARRAQRHATSDWMEMEQQRGISITSTVLQFEYQGYQINLLDTPGHQDFSEDTYRTLAAADNAVMLVDAAKGLEPQTRKLFEVCKLRSLPIFTFINKLDRPGREPLDLLDEIEKELGLQTYAVNWPIGMGDRFKGVYDRRLQQIHLFERTAHGKREARDTIVDLGDPQIEALLDQDLYFQLKDDLELIEGLGPELDLEAVHQGKMTPIFFGSAMTNFGVELFLNAFLDYALKPATYRSSQGAIAPTHEDFSGFVFKLQANMDPKHRDRVAFVRVCAGKFEKDMTVNHARTGKMIRLSRPQKLFAQGRESLETAYAGDVIGLNNPGVFAIGDTIYSGQKLEYEGIPCFSPELFAYLRNPNPSKFKQFQKGVSELREEGAVQIMYSVDESKREPILAAVGQLQFEVVQFRLQNEYGVETRIELLPYTVARWVVEGWPALEAVGRIFNAVTVKDSWGRPVLLFKNEWNAQQVLADHPKLKLSGIAPVVSGQQPEAL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LETM2_HUMAN
Sequence: MAFYSYNSVLAIARTRFPSHFVHPTCSSYSPSCAFLHLPDSHLNKTCMKNYESKKYSDPSQPGNTVLHPGTRLIQKLHTSTCWLQEVPGKPQLEQATKHPQVTSPQATKETGMEIKEGKQSYRQKIMDELKYYYNGFYLLWIDAKVAARMVWRLLHGQVLTRRERRRLLRTCVDFFRLVPFMVFLIVPFMEFLLPVFLKLFPEMLPSTFESESKKEEKQKKKMAVKLELAKFLQETMTEMARRNRAKMGDASTQLSSYVKQVQTGHKPSTKEIVRFSKLFEDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEEQLRQQLTEWQDLHLKENVPPSLLLLSRTFYLIDVKPKPIEIPLSGEAPKTDILVELPTFTESKENMVDLAPQLKGTKDEDFIQPPPVTSSPITPSTPISLPKGPITSSEEPTLQAKSQMTAQNSKASSKGA
What are the official names of this protein?
LETM1 domain-containing protein LETM2, mitochondrial, LETM1 and EF-hand domain-containing protein 2, Leucine zipper-EF-hand-containing transmembrane protein 1-like.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YHAM_ECO8A
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.