PharMolix/UniProtQA huggingface dataset:
Protein: IOVO_TYMCU
Sequence: LAAVSVDCSEYPKPACTMEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPX_PASMU
Sequence: MEKDTELHCSFCGKEQKHVSKLIAGTSGYICNECIELCHDMLLSDAVETPEVESTEQQKLPTPHEIRAHLDDYVIGQDYAKKVLSVAVYNHYKRLRSDKQITDVELGKSNILLIGPTGSGKTLLAETMARMLNVPFAMADATTLTEAGYVGEDVENVLQKLVQSCDYDVERAEQGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPQQEMLRVDTSKILFICGGAFAGLDKVIEKRVHVGSGIGFSAEVKSKQDKATLSQLFEQVEPDDLMKFGLIPEFIGRLPVVAPLAELDEEALVKILTEPKNALIKQYQALFSLEDVALEFSPEALTAMAKKALARKTGARGLRSIVEAILLDTMYDLPSLQHLEKVIVEASTITDNQPPTLVYKA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: GCS2_SALCH
Sequence: MALNDFHVSEPYTLGIELEMQVINPPSYDLSQDSSTLIDAVKSRLTAGEIKHDITESMLEMATGVCRDIDQAAAQLSAMQHVILQAASEHHLGICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCANGDDAIYLLHGLSHFVPHFIALSAASPYMQGSDTRFACARLNIFSAFPDNGPMPWVSNWQEFAGLFRRLSYTTMIDSIKDLHWDIRPSPAFGTVEVRVMDTPLTLDHAINMAGLIQATAHWLLTERPFKPQEQDYLLYKFNRFQACRYGLEGVLTDAYTGDRRRLADDTLRLLDNVTPSARKLGADSAIDALRLQVKKGGNEAQYMREFIADGGSLIGLVQKHCEIWAGQ
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: MSHR_MACSY
Sequence: MPVQGSQRRLLGSLNSTPTATPHLGLAANQTGARCLEVSVPDGLFLSLGLVSLVENVLVVTAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVTLLLEAGALAARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVLCSTLFIAYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRLAHQGFGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLALIICNAIIDPLIYAFRSQELRRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G6PD1_MYCTO
Sequence: MVDGGGGASDLLVIFGITGDLARKMTFRALYRLERHQLLDCPILGVASDDMSVGQLVKWARESIGRTEKIDDAVFDRLAGRLSYLHGDVTDSQLYDSLAELIGSACRPLYYLEMPPALFAPIVENLANVRLLERARVAVEKPFGHDLASALELNARLRAVLGEDQILRVDHFLGKQPVVELEYLRFANQALAELWDRNSISEIHITMAEDFGVEDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGSSADDLNDKKAEVFRAMAPLDPDRCVRGQYLGYTEVAGVASDSATETYVALRTEIDNWRWAGVPIFVRSGKELPAKVTEVRLFLRRVPALAFLPNRRPAEPNQIVLRIDPDPGMRLQISAHTDDSWRDIHLDSSFAVDLGEPIRPYERLLYAGLVGDHQLFAREDSIEQTWRIVQPLLDNPGEIHRYDRGSWGPEAAQSLLRGHRGWQSPWLPRGTDA
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase 1, G6PD 1.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: FABZ_STRPM
Sequence: MDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFFNGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGG_SALPA
Sequence: MMKMRWLGAAIMLTLYASSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNSDKAYWNNLKTPFKLEFYHQGMYFDTLVKINEVTATTVKRIKYSPDYFNFGNVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFREFWIERPKPTDKRLTVYALLDSPRATGAYRFVIIPGRDTVVDVQSKVYLRDKVGKLGVAPLTSMFLFGPNQPSPTTNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSYAMENPQGFGLLQRGREFSRFEDLDDRYDLRPSAWITPKGDWGKGKVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTLTFSRDEDKLHAPDNAWVLQTRRSTGDVKQSNLIRQPDGTIAFVVDFVGADMKKLPPDTPVAAQTSIGDNGEIVDSNVRYNPVTKGWRLMLRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS10_LACE2
Sequence: MANQVIRITLKAYDHQLIDQSAKKIIETAKKTGAQVSGPVPLPTKKEVVTILRAVHKYKDSREQFEQRTHKRLIDVLSPSQKTVDALSKLEMPAGVFINLKVMN
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: YFII_BACSU
Sequence: MMLNGERIISKPLRWAMVGGGRLSQVGYKHRIGALRDNTAFQLTAGAFDIDAERGKDFGVNLGVDAERCYPNYQTMFAEEAKRQDGIEVVSIATPNGTHYEICKAALEAGVHVICEKPLFFTSAEGQEIKALAEKKGKIVGVTYGFSGNQMLLQMRAMIEQGMIGDIRVVDLQYTHGFCATDEGEKISAAQKWRVDPAIAGPSFVLGDLSTHTYYMSQLIMPKMKIKELLCDRQSFVGSRAPLEDNAHVLMHYENGAVGTMWTSSINAGCMDGHRIRIVGSKASIEWWDSKPNELTYEVQGEPGQTLVRGMPYLDDVCNADERLGALHSEGLSEAWANIYLKFAIAIDAKNREDEEILNNLVYPDIDAGIEGIRWIENCVRSANQGSVWVEFK
What are the official names of this protein?
Uncharacterized oxidoreductase YfiI.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: LOX_LYSSC
Sequence: MTNTTDGDLLLKNITAQAPFPICFADLEKAVAEKIPAGPFGYIRSGAGGEQTLRNNRSAFEKYSIVPRFLNDVSNVHTSINLFGKTYPTPLLFAPVGMNGMVHEEGELAAVRAAQQLNMPYIQSTVSTYALEDVAEAAPSATKWFQLYWSTNEEIAFSMAARAESAGFEAIVLTVDTVMLGWREEDVRNQFSPLKLGYAKGNYINDPVFMASLPNDSFESYVQGVLQNVFHPTLNWEHVRELKRRTNLPILLKGILHPEDAKLAIVNGVDGIIVSNHGGRQLDGVIGSLDALPSIVSAVKGQIPIILDSGVYRGMDALKALALGADAVAIGRPFIYGLALEGQQGVERVMTNIYDELKVSIALAGTTSIEGLRTITLVKNDGMEVK
What is the function of this protein?
Oxidase that catalyzes the oxidation of a broad range of 2-hydroxyacids in vitro, such as (S)-lactate, 2-hydroxyoctanoate, mandelate, 2-hydroxyoctadecanoate and (S)-2-hydroxyglutarate, to the corresponding 2-oxoacids, with a reduction of O2 to H2O2 (PubMed:34555022).  May be involved in the utilization of L-lactate as an energy source for growth (By similarity).
What are the official names of this protein?
L-lactate oxidase, LOX, (S)-2-hydroxy-acid oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Protein: PYRC_ORYSJ
Sequence: MQTAATSTFFANPHVKHLPGPFLRPSPHYGALVHLPSFRNKTPISIAMAASPSPPPLQELTITRPDDWHLHLREGDVLAAVLPHSAMHFGRAIVMPNLKPPVTTTARALEYREEILRALPPGSNFVPLMTLYLTDNTSPEEIKLAKKSGVVFAVKLYPSGATTNSQDGVTDIFGKCLPVLEEMARQEMPLLVHGEVTDQHVDTFDREKVFIEKILAPLVQRLPQLKIVMEHITTMDAVNFVESCKEGHVAATVTPQHLLLNRNALFQGGLQPHNYCLPVLKRETHRQAIVSAVTSGSKQYFLGTDSAPHDKRRKECSCGCAGIYSAPVALSLYAKVFEQAGALDKLEAFTSFNGPDFYGLPRNTSKIVLRKSAWKVPDTYSYSSGEIVPMFTGNTLEWLPSDQLEE
What are the official names of this protein?
Dihydroorotase, mitochondrial, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TGM4_HUMAN
Sequence: MMDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDCCISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLITK
What is the function of this protein?
Associated with the mammalian reproductive process.  Catalyzes the cross-linking of proteins and the conjugation of polyamines to specific proteins in the seminal tract.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase 4, Fibrinoligase, Prostate transglutaminase, Prostate-specific transglutaminase, Transglutaminase P, TG(P), TGP, TGase P, Transglutaminase-4, TGase-4.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
Protein: M2K1C_PHYPA
Sequence: MSRRVRRGGLRVAVPKQETPVSKFLTASGTFQDDDIKLNHTGLRVVSSEPNLPTQTQSSSPDGQLSIADLELVRFLGKGAGGTVQLVRHKWTNVNYALKAIQMNINETVRKQIVQELKINQVTHQQCPYIVECFHSFYHNGVISMILEYMDRGSLSDIIKQQKQIPEPYLAVIASQVLKGLEYLHQVRHIIHRDIKPSNLLINHKGEVKISDFGVSAVLVHSLAQRDTFVGTCTYMSPERLQGRSYAYDSDLWSLGLTLLECALGTFPYKPAGMEEGWQNFFILMECIVNQPPAAASPDKFSPEFCSFIESCIRKCPSERPSTTDLLKHPFLQKYNEEEYHLSKIL
What is the function of this protein?
The CERK1, MEKK1a/b, MKK1a/b/c and MPK4a/b proteins are involved in pathogen defense.  The pathway induces rapid growth inhibition, cell wall depositions and accumulation of defense-related transcripts.  This protein is required for full defense response to fungal pathogen chitin.
What are the official names of this protein?
Mitogen-activated protein kinase kinase 1c, MAP kinase kinase 1c, PpMKK1c.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: UBP36_DROWI
Sequence: MPVSLAVCETTTTTTANVVNAALRESLLGGSRSGAAVAGSGSASSLISGAGGAGASAANDDDSSSTATANTNLQNQIVASAKRVLLAKIEYEEVENYNDSVLDNLKTKYVVIKSPTPAAAAAATNNGNSNSAGSKILGANGHDNRQKQQNANGGCSTPTTTTTQTSSSSTSSSSIEHNNNPNELPKPKRVLYQRENIRIGWKQSERKWQIGAGMINVGNTCYLNSTLQALFHIPALANWLNSEQSHLENCNIGGESGGGGGGGGGNNGGFCIICAMAKTLQSTQSNASAIRPYHIYSKLKQICKHMVIGRQEDAHEFLRFLVEAMEKAYLMRYRNYKELDQLVKETTPLNQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKSDTLDEAFDGYFSRERLEDMGYKCEGCKKKVSATKQFSLQRAPITLCIQLKRFSMIGNKLTKQISFKPRIDLSRFAARSPTAQGQLPLTYRLVSLVTHLGVSQHCGHYTAIGLTESGSYYNFDDSYVRPIAMQSVCSTNSYIMFYELDLNQPLATPANKLNGLRQLSNGHHHHQQQQQQHQQQQQQQPTVVATIASSPMATTRFIGPQLPPGGLNGYAMTTTTTATNNTTNGHSQKTAIQFKPQQNGILTVGSGKFQESGQQKSPLVGTNHKNEAPAVAPNANANANGKSSSNPNTNTTINTNTNNGNSNNNNTNATTANNSNKLNQQQQQYLPMSSSDEEDSDEEKMKRPTTTTPQLPSMPKMDGGGDEKPKTLTLTPTTTPTASTPTVSNPLKRLVPYESASEEEESSSGTPSSSTPTTTTTAAAAAASSPMQATAAATLPPPPTPTNARKRSLPDHHHHHPHHHVMVNGHGKSPKPASMPPATNFNSSSSKQKTDAIDEIFKSLNNFNKKRINNKNQKHNEGDEEEDDEETLEKETNNSSRLVSSSTNTSPTTNGWKQSQIVSSSSSNSKNVSTSAAAAAATTSSSTSTSAPPSPKTPPSPAVINSKTGLWKVTRNLDDDDDEEEEDEDDEEHIAPTPPPVVAKTHKNPFSSQQKPTPSPSTEAAPKRQKLFNGTSSSTPHVGNGYQSEPSTPNGGGSGSGSNGCLNELLKQSHRGYGSSSVLSWNGKQTELDKEPFELVCAKRIAVDHGDHDDGGGGDDGGGVGVVTTTTTTTTTTKNTTKTLTADAQEQRQRDLDDDEENEMDRGRQRKVKTATANGKSSGNSNNTTPGYNPFQEYESQKRWHNKSSNGPPRFYTQHASSSYRSNFHQRNKFKCNRGGNGGGGSGGISKFDHRHGLQRHLAAGGGFPRRPNANQQQQQQQS
What is the function of this protein?
Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells.  May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).  Controls selective autophagy activation by ubiquitinated proteins.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 36, Deubiquitinating enzyme 36, Protein scrawny, Ubiquitin thioesterase 36, Ubiquitin-specific-processing protease 36.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FRDC_KLEP7
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMVREGTAVPTVWFSIVLIYGLFALKHGADSWAGYIGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANVIIKGEKMGPEPVIKGLWVVTAVVTVVILFVALFW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZAPA_HAEIE
Sequence: MSLKLVEILVLGQVLRLNVPIEQEELLRQAARNLDILVSEMKEKTGLIQLDRVLSIVALNLSFELSQEKNKTAKIEEVLRTGIQQLDHSLENIRVTKEPH
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division (By similarity).
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid- cell.
Protein: RSMH_COPPD
Sequence: MTNYIEHKPVMAKQVAELLVSNEEGIYVDATAGSGGHLGLLANTYPEASFIGIDIDPEAVKFLTEKFAGVSNVRIIRGNYADLPDILHSMEIGQVDGILLDLGISMHQALSAQRGFSIKNPGPLDMRFSIDQKVTAYELVNSLSEEQLADIIYRYGEERRARKIAKAVVEARKVKPLETTDELADLVARTVGYRGRIHPATRVFQALRIATNRELDNLQVALPRIFQVLKEGGRLAVISYHSLEDRIVKQFFKTWEEEGKGLRLTKKVVKPSLEEINENPSSRSAKLRVFKKGVGGNEN
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPE_CITFR
Sequence: MQTQKPTLELVACDAAYRENPTALFHQVCGARPATLLLESADIDSKDDLKSLLLVDSALRITAIGDTVTIQALSANGASLLPLLDAALPAGVENKQQPNGRHLRFPAVSPLLDEDVRLRSLSAPDAFRPLQELVNVPAQEREVMFLGGMF
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: ATPG_CYTH3
Sequence: MPSLKEVRNRIASVNSTQQITKAMKMVSAAKLRRAQDRAMKIRPYAEKLNGILQNIAASLEDGADNVYAEERELKRLLIVVVTSDRGLAGAFNANIVKAANALIEEKYSNLYQANKVDFICIGKKGAEAITKRGESANLEYQGLFQNLSFDTARGASEYVMNAYLTGKYDRVEVIYNEFKNVATQIIRTEQFLPIKGQALSAVKHSATEVDYIFEPSKEEIVKELIPKSLKVQFYKYLLESNASEHGARMTAMDKATENAKEMLKALKLTYNRSRQAAITKEILEIVGGAEALNN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y849_HELAH
Sequence: MEKLPRKRVSKTKSQKLINSLTTQKNRALLKKISSNEMLLELEKGAFKKNEAYFISDEEDKNYVLVPDNVISLLAENARKAFEARLKAELERDIIIQAPIDFEDVREVSLQLLENLRQKDGNLPNINTLNFVKQIKKEHPNLFFNFDNMFKQPPFNENNFENFDSNDEENF
What are the official names of this protein?
UPF0763 protein Hac_0849.
What is the protein family that this protein belongs to?
Belongs to the UPF0763 family.
Protein: MSCS_SHIFL
Sequence: MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLIIARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGAAGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADGKIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKDREMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVNFKRVKEDKAA
What is the function of this protein?
Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins.  Contributes to normal resistance to hypoosmotic shock.  Forms an ion channel of 1. 0 nanosiemens conductance with a slight preference for anions.  The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa.  The channel is characterized by short bursts of activity that last for a few seconds.
What are the official names of this protein?
Small-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHAF1_MOUSE
Sequence: MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIRNVQVLYSEQSPLSHDLILNLTQDGITLLFDAFNQRLKVIEVCELTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSTEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPVMPLSCFLGNVYAESVDVLRDGTGPSGLRLRLLAAGCGPGVLADAKMRVFERAVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENAGGQTEICTTYSKWDSIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP
What is the function of this protein?
Plays a regulatory role in autophagic activity.  In complex with BCAS3, associates with the autophagosome formation site during both non-selective and selective autophagy.
What are the official names of this protein?
Phagosome assembly factor 1.
What is the protein family that this protein belongs to?
Belongs to the PHAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure. Note=The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner.
Protein: HN_NDVA
Sequence: MNRAVCQVALENDEREAKNTWRLVFRIAILLLTVMTLAISAAALAYSMEASTPGDLVSIPTAISRAEGKITSALGSNQDVVDRIYKQVALESPLALLNTESIIMNAITSLSYQINGAANNSGCGAPVHDPDYIGGIGKELIVDDTSDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHCYTHNVIFSGCRDHSHSHQYLALGVLRTSATGRVFFSTLRSINLDDTQNRKSCSVSATPLGCDMLCSKVTETEEEDYNSVIPTSMVHGRLGFDGQYHEKDLDVTTLFGDWVANYPGVGGGSFIDNRVWFPVYGGLKPSSPSDTGQEGRYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRVQQAILSIKVSTSLGEDPVLTIPPNTVTLMGAEGRVLTVGTSHFLYQRGSSYFSPALLYPMTVNNNTATLHSPYTFNAFTRPGSVPCQASARCPNSCVTGVYTDPYPLVFHRNHTLRGVFGTMLDDEQARLNLVSAVFDNISRSRITRVSSSRTKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKDDGV
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: NUOD_HALHL
Sequence: MAEFQSYTLNFGPQHPAAHGVLRLVLEMEGEAVRRADPHIGLLHRATEKLAESKPYNQSIGYMDRLDYVSMMCNEHGYVRAIEKLLGIEPPLRAQYIRTMMDEVTRILNHLMWLGGHGLDVGAMTAFLYTFREREDLMDVYEAVSGARMHATYYRPGGVHRDLPDQMPKYEPSAYRSDKELREMNRAREGSVLDFLDDFCERFPACVDEYETLLTENRIWKQRLVDICPVSAERAVELGFTGPLLRGSGVAWDLRKKQPYAAYDRVDFDIPVGVNGDSYDRYLVRVEEMRQSVRIIKQCVDWLRANPGPVRIDDPKVTPPTREEMKDDMESLIHHFKLFTEGYCTPPGEVYAAVEAPKGEFGVYLISDGANKPYRLKVRPPCYYHLAATDEMIRGYMLADVVTLIGSLDVVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NADD_ECOL6
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSMQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: EFPL_YERPN
Sequence: MAKANEIKRGMAVNLNGKLLLVKDIDVQSPSARGASTLYKMRFSDVRTGLKVEERFKGDENLDTITLTRRAVNFSYIDGDEYVFMDDEDYTPYNFKKEQIEDELLFIPEGGMPGMQVLTMEGQLLALELPQTVDMEIVDTAPSIKGASASARNKPAIMSTGLSIQVPEYISPGEKIRIHIAERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: DAPB_STAAC
Sequence: MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKGADVAIDFSNPNLLFPLLDEDFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKENVTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.