PharMolix/UniProtQA huggingface dataset:
Protein: RPB2_ASHGO
Sequence: MLEYYDDDAYVYDDDDEDAPITAEDSWTVISAFFREKGLVSQQLDSFNQFINYTIQDLILEDSTLILEQLAQHTTEADNISRKYEISFGKIYLAKPSMTESDGVSHAMYPQEARLRNLTYASGLFVEIKKRTYEAVDIPGRDLKYEIIQEESEDTEEGKIFIGRVPIMLRSKYCLLDDLSESDLYRLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKSAPSPISHIAEIRSALEKGSRFISTLQVKLYGREGSTSRTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDQNDWQMLEMLKPCVEEGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFRKLTRDILRFMQRSVEEAKDFNLKLAVKATTITAGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPVPIITFLNEWGMEPLEDYVPHQSPDATRVFVNGVWHGIHRNPARLVDTIRKLRRKGDITAEVSIVRDIREKELKIFTDAGRVYRPLFVVADTQHADGHKDLKVRKGHIRKLMLTEYQDIEGGFEDEDINYTWTSLLNDGIVEYIDAEEEETILIAMQQEDLDPSVPQTVDPSDELDPARRIKAIHHSNTFTHCEIHPSMILGVAASVIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDSGLFRSLFFRSYMDQEKRIGMSITESFEKPHRTNTLRMKHGTYEKLDDDGLIAPGVRVSGDDIIIGKTTPIPPDAEELGQRTAFHSKRDASTPLRSTENGIVDQVLITTNQEGLKFVKVRVRTTKVPQIGDKFASRHGQKGTIGITYRREDMPFTAEGVVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVDGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAAFLKERLMEASDAFRVHICGICGLMTVVAKLKHNQFECRGCKNKIDIYQVHIPYAAKLLFQELMAMNIAPRLYTDRSRDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB2, RNA polymerase II subunit 2, RNA polymerase II subunit B2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PANB_PSEPK
Sequence: MPEVTLTTLNGLKAKGEKITMLTCYDATFAKAASQAGVEVLLVGDSLGMVLQGHDSTLPVTTAEMAYHTASVKRGNDGALILTDLPFMAHATPEQAFANSATLMQAGAHMVKIEGAAWLAETIRLLAERGVPVCAHMGLTPQTVNVLGGYKVQGRQEAQARQMRADAIALEQAGAAMLLLECVPSELAAEITNAVGIPVIGIGAGSATDGQVLVLHDMLGLSLSGRVPKFVKNFMQGQPDIHSALVAYVEAVKQVSFPGSEHGFSA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_LATSS
Sequence: MKVAVDAMGGDFAPQSVIEGVLQARSEFTDLDFILYGDQAQIEPLIDDMTRLTIVHTTEKIASDDEPVRAIRRKKQASMVLAAQAVKDGQADALFSLGNTGALLAAGLFIIGRVKGIDRPGLMPTLPSINSDQGFNMLDVGANAEAKPEHLHQYGLMGNFYAKDVRGIENPRIALLNNGTEATKGDELHKATYQLLADDPDLNFVGNVEANDLLKGVADVVVTDGFTGNATLKAIEGTATIVMSQVKHAIMDAGVKEKIGGLLLRGSVGGIREKFDTSIYGGAVLLGLKAPVIKAHGAADARTVYYTVKQIHAMLANQTVQKVIDYFSDQAAQKNSN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RS9_KINRD
Sequence: MSEYTTEADTVEDITESDEFTGTYTSESSTPATGGNSIIAPGGATGRRKEAVARVRIVPGTGKWTINGRELDNYFPNKVHQQLVNEPFRVTALEGSFDVIARIHGGGSSGQAGALRLGVARALNAIDLEANRPQLKKAGFLTRDPRATERKKAGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: PURP_PYRNV
Sequence: MLISGANPTHVSAALKRYDVEKLAVATVASHTALQILRGAKRFGFRTIAVAGRADAAEFYRQFGFIDEVWTADFRNFVKTAEKLVEANAVLVPHGSYVEYVGWRQALEAPVPTLGCRELIRWEADQYKKMELLQRAGVPTPRVYKTPEEVDRPVIVKLFGAKGGRGYFLARDREELRRRLAGLGEYIIQEYVFGVPAYYHFFSSPVYGRVEVFGADIRYESNVDGRTFGWVEPTFVVVGNLPLVLRESLLPTIWKYGVQFAKAVEEAVGCRLAGPYCLESIIRDDMSISVFEFSGRIVAGTNIYMGYGSPYSVLYFDRPMDMGERIAHEIREAARRGRLEDLFT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RS5_LIMRD
Sequence: MASSEFIDPAKLDLDDQVVAINRITKVVKGGRRMRFAALVIVGDRKGHVGFGTGKAQEVPEAIRKAQAAAEKNLITVPIVGTTIPHEVIGVYGGGKIMLKPAVEGSGVAAGGAVRNVMDLAGVADVTSKRLGSNTPVNVVRATFEGLKQLKNAEEVAKLRGVSVDHLAE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y132_TREPA
Sequence: MEPRMSGSNLRFPYSRAYGGAGVGRNFEKSSRFSVQKEGIGAPGSARTALQFKLFLLSRLFFIFTSHIP
What are the official names of this protein?
Uncharacterized protein TP_0132.
Protein: GOSR2_HUMAN
Sequence: MDPLFQQTHKQVHEIQSCMGRLETADKQSVHIVENEIQASIDQIFSRLERLEILSSKEPPNKRQNARLRVDQLKYDVQHLQTALRNFQHRRHAREQQERQREELLSRTFTTNDSDTTIPMDESLQFNSSLQKVHNGMDDLILDGHNILDGLRTQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCVVMFLVVQYLT
What is the function of this protein?
Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
What are the official names of this protein?
Golgi SNAP receptor complex member 2, 27 kDa Golgi SNARE protein, Membrin.
What is the protein family that this protein belongs to?
Belongs to the GOSR2 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein. Golgi apparatus membrane. Endoplasmic reticulum membrane. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus.
Protein: RECA_PARMW
Sequence: MPAEMKSAASGSDPRSSGERDKALNLVLGQIERNFGKGSIMRLGDASRMRVETISTGALTLDLALGGGYPKGRVVEIYGPESSGKTTLTLHAIAEVQKRGGVAAFVDAEHALDPVYAASLGVDVENLLVSQPDTGEMALEIVDQLVRSAAVDIVVIDSVAALTPRAEIEGEMGDLAVGSQARLMSQAMRKITGNIGKSGCTVIFLNQLRLKIGVTYGNPETTTGGNALKFYASVRLDIRRIQTLKKGTEEFGIRAKVKVAKNKVAPPFRIAEFDILFGRGISTLGCLLDLAEETGVVIRKGAWYSYEGDNIGQGRDNTITWMEENPEAAITIEQLVRQKLTEGSEVKANSMKPLAAAARTAAAAAPKATADEAAA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_PEA
Sequence: MKVAASVRKICEKCRLIRRRGRLLVICSNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DXR_BACFN
Sequence: MNEIKKKQIAILGSTGSIGTQALQVIEEHPELYEVYALTANNKVDLLIAQARKFMPEAVVIANEEKYAQLKEALSDLPVKVYAGAAALCQIVESGPIDVVLTAMVGYAGLKPTMNAIRAGKAIALANKETLVVAGELINQLARQYRTPILPVDSEHSAVFQCLAGEVGNPIEKVILTASGGPFRTCTMEQLKTVTKVQALKHPNWEMGAKITIDSASMMNKGFEVIEAKWLFGVQPSQIEVVVHPQSVIHSMVQFEDGAIKAQLGMPDMRLPIQYAFSYPDRINSSFDRLDFSKCTNLTFEQPDTKRFRNLALAYESMYRGGNMPCIVNAANEVVVAAFLRDEISFLGMSDVIEHTMGQVSFVQTPTYDDYVATDAEARRIARELICK
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: YIDC_BRUSU
Sequence: MENKRNFFITIALSILILALWQVFYLGPKTEAQREQARIEEQQRQAQQAAQNRQASSSTGDTPQMPANPDSIPGQGDTKAAGAPLTRDAAIAQSPRIEIDTPSLRGSINLTGARLDDLYLKKYHETVSDKSPEIELLAPSSLKQGYFVELGFTGNDATGAVPGPNTVWVVEGNNKLTPSTPVTLTYTNDKNLTFKRVISVDDAYMFTVDDTIINNGGSTVSLASYGRVTRFNQPEHASATYVLHEGLIGVMGQDGLQEIKYAKIKDNKDISFKDVIGGWVGITDKYWAATLIPPQDEKFTGRFSHFTNDRPRYQSDLLSAPLTVAPGQSQKIQNRVFAGAKVVNTIQNYETKYHIKQFDLLIDWGWFYFITKPMFYLIDWIYKFTGNFGVAILVVTVLLKALFFPLANKSYKSMARMKLMQPKMTEIREKYADDKMKQQQAMMELYKREKINPLAGCWPVLVQIPVFFALYKVLYVTIEMRHAPFFGWIQDLAAPDPTSIFNLFGLLPYTVPHFLMIGVWPIIMGITMFLQMRMNPTPPDPTQAAIFTWMPIIFTFMLASFPAGLVIYWAWNNTLSIIQQSVIMKRQGVKIELFDNLKGLFRRKPKEANK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CODY_BACSU
Sequence: MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLFNVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNNKFLIELENLKSH
What is the function of this protein?
In B. subtilis, CodY targets include several hundred genes involved in many different processes, including sporulation, competence, transport systems and catabolic processes (PubMed:12618455, PubMed:23569278).  CodY bound to GTP represses many stationary-phase and some early-sporulation genes during growth in excess nutrients (PubMed:11331605).  Among others, it binds to the ilvB promoter region and mediates regulation of the ilvB operon by GTP and branched-chain amino acids (BCAAs) (PubMed:15228537, PubMed:17993518, PubMed:18083814, PubMed:19749041).  It represses expression of the dipeptide transport operon (dpp) during the exponential growth phase in rich medium (PubMed:7783641, PubMed:11331605, PubMed:18083814).  Is also involved in the repression of competence by casamino acids via direct binding and repression of the srfA and comK promoter regions (PubMed:8830686).  CodY acts predominantly as a repressor of transcription, but it can also activate transcription of a few genes, including the acetate kinase gene ackA, whose expression is primarily dependent on BCAA levels and only secondarily on GTP levels (PubMed:16995897).  Binds to a 15-bp canonical consensus DNA motif, the CodY-binding site (PubMed:18083814, PubMed:21764931, PubMed:23569278).  CodY operators may contain multiple CodY-binding sites with 6-bp overlaps (PubMed:21764931).  Most CodY-binding sites are in intergenic regions, but sites located within coding regions were also identified (PubMed:23569278).
What are the official names of this protein?
Global transcriptional regulator CodY, Branched-chain amino acid-responsive transcriptional regulator, GTP-sensing transcriptional pleiotropic repressor CodY, Vegetative protein 286B, VEG286B.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_SHEPW
Sequence: MSKKYVIALDQGTTSSRAIVFDHDANMVASSQREFGQIYPQPGWVEHDAMEIWASQSSTLIEALARADIHSEDVAAIGITNQRETTVIWDKMTGKPVYNAIVWQCRRSKAICDELKAQGLEEYVKDCTGLLLDPYFSGTKIKWILDNVEGVRERAEKGELLFGTIDTWLVWKLTEGKVHVTDPTNASRTLLFNIHQQAWDEKLLNALGIPRSLLPEVKPSSAIYGQTRIAGEGSSIAIAGIAGDQQSALFGQLCIDEGMAKNTYGTGCFLLMNTGTEAVKSQQGLLTTIAVGAKGEVNYALEGSVFMGGATIQWLRDELGLIRDAQDTEYFASKVENTNGVYLVPAFVGLGAPYWDPDARGALVGLTRGANRNHIIRAALEAIAYQSRDLLDAMSKDSGVELKQIKVDGGAVANDFLMQFQADITNVDVLRPELTETTAMGAAFLAGLAVGFWSSTAELKHKAGIERRFKPKINDAQRATLYDGWKEAVARTR
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MURD_STRPG
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPLLTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLNDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_SHEFN
Sequence: MAELKNDRYLRALLKQPVDVTPVWMMRQAGRYLPEYKEVRAQAGDFMSLCRNAELACEVTLQPLRRYDLDAAILFSDILTVPDAMGLGLYFEAGEGPRFERPTDTIDAIKKLCIPDPEDELGYVMRAVSTIRRELNGSVPLIGFSGSPWTLATYMVEGGSSKTFEKIKRMAYAEPAALHMLLDKLADSVVLYLNAQVANGVQSLMIFDSWGGALSHHAYREFSLRYMQKIVDGLTRFADGRKVPVTLFTKGGGLWLESMAETGCDALGLDWTVDIGDARRRVGHKVALQGNMDPSMLYATPERIHQEVDQILASYGEGTGHVFNLGHGIHQHVDPEHAGAFINSVHELSGKYHK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAF_DROMO
Sequence: MMMTKQKPTLTERLNIGGDEVRELKLGATFNPKNTATAFHTIKYDFKPASVDTSRMATVDVGSNNQVTVTVPNLESSGVPQTVYKGNHKKYTKECLIIFDKETGAITLEKLNHNIQVKKTRSEMTNKPSLMPATNAAPMSSGPNGVPMPSGAMAGTGSGPKLENSTMRITSKTKVSTGSRRNNIIDFKPRNSPMQQSSPSRPVASHRSPQSAPAWHANNAQQTLPSIPMIMDDDDFGLSAALHNGGGGGGGQANISGSSTGSSVGQPDYGSVNMGKQRQASSQGHAKRQQQTQRSSPPMQQQQQQQNYGRGGANNNYAQQLHQQQQQQQQQQLQQQQQQMQQRASFSHSNHSNSMPLDLDSPTHHEQAAQSMAQAAAVLEQQIGGELSASSSSSESESSDSDSGSDSDDSTEDDRSTHQQQQPPGQLSQHHHHHMQQQQHMHQLPNLGLGSISPTYNSHQHHQQQQQQHQQQQQQQSHHHHHQQQQQQSSIYASNGGFPNDLLQNDLQLSSNSSDDDD
What is the function of this protein?
Promotes transcriptional elongation by Su(Tpl)/ELL.  Essential for development (By similarity).
What are the official names of this protein?
Ell-associated factor Eaf.
What is the protein family that this protein belongs to?
Belongs to the EAF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OXSR1_PIG
Sequence: MSEDSSALPWSINKDDYELQEVIGSGATAVVQAAYCTPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEATIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEYLQEKILQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESLTNSELFSTTHPVGTLLQVPEQISAHLPQSAGQMPAQLTPVSLPPAAELAPVQAAQAQSSGAGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDSKLIGFAQLSIS
What is the function of this protein?
Phosphorylates RELL1, RELL2, RELT and PAK1.  Phosphorylates PLSCR1 in the presence of RELT.
What are the official names of this protein?
Serine/threonine-protein kinase OSR1, Oxidative stress-responsive 1 protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAV1_HORSE
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNVRINLQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: RS2_SALEP
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKISARKGKILFVGTKRAASEAVKEAANSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVSLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y2588_VIBPA
Sequence: MSEITLPEYQSIAAELQSASLAVTPAELHGLLVGMLSGGLAINDQTWQPILFDYTNDGMGWPTTALAFAQTVFKVTANELTGSSMELSLLLPDESGEEGLFALADSLSDFVNHFISGLGLAGIALNNASDDAKEALADLEEIAKLGIDEDDDFGEQAQLLEQVIEHVKACVLTIHAEFGARPESSESKPTIH
What are the official names of this protein?
UPF0149 protein VP2588.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: Y2071_STRP8
Sequence: MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
What are the official names of this protein?
UPF0337 protein spyM18_2071.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: TLP4_TAXBA
Sequence: DDPTSTFTCPGGSNYK
What are the official names of this protein?
Thaumatin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: RPA34_HUMAN
Sequence: MEEPQAGDAARFSCPPNFTAKPPASESPRFSLEALTGPDTELWLIQAPADFAPECFNGRHVPLSGSQIVKGKLAGKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEGPQQSLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRKQQQQQPV
What is the function of this protein?
Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA34, A34.5, Antisense to ERCC-1 protein, ASE-1, CD3-epsilon-associated protein, CD3E-associated protein, DNA-directed RNA polymerase I subunit G, RNA polymerase I-associated factor PAF49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPA34 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome. Note=Found at the fibrillar centers of the nucleolus in interphase and during cell division it is localized to the nucleolus organizer regions of the chromosomes.
Protein: TLDD_SHIFL
Sequence: MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA
What is the function of this protein?
Metalloprotease involved in CcdA degradation.  Suppresses the inhibitory activity of the carbon storage regulator (CsrA) (By similarity).
What are the official names of this protein?
Metalloprotease TldD homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase U62 family.
Protein: CBPA_SALSV
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQLWQHRNDPQFNRQFQQHEGQPYNAEDFDDIFSSIFGQHGRHSHHRHAARGHDIEIEVAVFLEETLEEHQRTISYSVPVYNAFGLVEREIPKTLNVKIPAGVSNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVNQDLEVVLPLAPWEAALGAKVSVPTLKERILLTIPPGSQAGQRLRIKGKGLASKKHTGDLYAIIKIVMPPKPDEKTAALWQQLADAQSSFDPRQQWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TRPA_PSEAE
Sequence: MSRLQTRFAQLKQENRAALVTFVTAGDPDYASSLEILKGLPAAGADVIELGMPFTDPMADGPAIQLANIRALDGGQTLARTLQMVREFRSGDSETPLVLMGYFNPIHHYGVERFIAEAKEVGVDGLIVVDLPPEHNEDLCHPAQAAGIDFIRLTTPTTGDQRLPTVLEGSSGFVYYVSVAGVTGANAATLEHVEEAVARLRRHTDLPIGIGFGIRSAEHAAAVARLADGVVVGSALIDRIAKARDNAQAVKDVLALCGELAEGVRNAR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.