PharMolix/UniProtQA huggingface dataset:
Protein: GLMM1_SHESR
Sequence: MSERKFFGTDGIRGKVGSGQMTPELALKLGWAAGRVLSRSGTNKVIIGKDTRISGYMFESALEAGLSAAGLNVMLMGPMPTPAVAYLTRTFRAEAGVVISASHNPYYDNGIKFFSNDGSKLDDNLELEIEAELEKPLECVESHLLGKVSRIEDARGRYIEYCKGNFPADQTLTGLKIVVDCAHGATYHIAPAVFRELGAEVIAIGDKPNGVNINDKVGATSMAKICETVLTEGADLGIALDGDGDRIMMVNSRGEVIDGDQILYILACDAKARGVLRGGVVGTLMSNLGLDLALQALDIPFARSKVGDRYVMELLKELDWRIGGENSGHILNLDHGTTGDGIVAGILVLAAMRRQNATLEQLTAPMEMLPQVLVNVRFEGEHDPLSSDKVKAAQAQVESQLGARGRVLLRKSGTEPLIRVMVEGDDHNTVLAHANLIADAVKSAS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: YBEY_LACDA
Sequence: MQGIDVSYSDEVGFLTKGDRDWEDWIMQLLLMAKKEIGKDNAQEMSINFVDEDRSQAINRDYRDKDRPTDVISFAIEDGDDGLDLSMFTQDPDFTEDIGDLFMCPSVIERHSKEYGTGFDREFGYTIVHGYLHLNCYDHIEPDEAKEMFGIQGKVLEEYGLPLYPDQLDEGRGK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX24_RAT
Sequence: MEVYIPSFRHEDSDLERGYTVFKIEVLMNGRKHFVEKRYSEFHALHKKLKKCIKTPEIPSKHVRNWVPKVLEQRRQGLETYLQAVILENEELPKLFLDFLNVRHLPSLPKAESCGSFDETESEESSKLSHQPVLLFLGDPYVLPAASDFPNVVIEGVLHGIFFSHLQPR
What is the function of this protein?
May be involved in several stages of intracellular trafficking.
What are the official names of this protein?
Sorting nexin-24.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYL_BRUAB
Sequence: MAAERYNPRVAEAHWQKVWEENRTFETDNSDSREKYYVLEMFPYPSGRIHMGHVRNYAMGDVVARYKRAKGFNVLHPMGWDAFGMPAENAAMQNKVHPKEWTYQNIATMKRQLKSMGLSLDWSREFATCDVEYYHRQQMLFIDLYEKGLVTRKTSKVNWDPVDNTVLANEQVVDGRGWRSGALVEQRELTQWFFKITDFSEELLAGLDTLDQWPEKVRLMQRNWIGKSEGLQVRFALAAGTAPAGFSEVEVYTTRPDTLFGAAFVAISADHPLAKKLSEGNAALSSFIEECHQQGTSLAALETAEKKGFDTGIKVKHPFDDNWELPVYVANFVLMEYGTGAVFGCPAHDQRDLDFANKYKLKVTPVVLPKGEDAASFSIGETAYTDDGVMINSRFLDGMTPEAAFNEVASRLEKTDLVGRPQAVRKVQFRLRDWGISRQRYWGCPIPMIHCESCGVNPVPRADLPVKLPDDVEFDRPGNPLDRHATWRHVKCPKCGGDARRETDTMDTFVDSSWYYTRFTAPWENEPTDRKAADHWLPVDQYIGGIEHAILHLLYSRFFTRAMKVAGHVGVDEPFKGLFTQGMVVHETYKANGQWVSPADIRIEEIDGKRVATMLDSGAPVEIGSIEKMSKSKKNVVDPDDIIASYGADTARWFVLSDSPPERDVIWTEAGAEGAHRFVQRIWRLVAEAAPALKDVAPKAGTQGEALGVSKAVHKAVKAVGDDIEKLAFNRGVARLYELVNTLSGALQQAADGKADAEMKGALREATEMLVLMTAPMMPHLAEQCLAELGGKVAGKETLVARAPWPVFDPALVVENEIVLPVQINGKKRGDLTIARDADQASIQQAVLELDFVKAALNGGSPKKIIVVPQRIVNVVA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUS3_CRYNB
Sequence: MTDDPAATPRPETSVNARPAFSGQAPIKAEYLINTTPIVESASASELNNIHPDDAAEGRTDSRDSRDGRDRPDNKRRKPNKQDKKDKKGQNKGRHFPVIREASVRICRAWETTGICDRADKGDCRYAHSWEGYFEVKPNDISYRPDWSLVGEAPFVVEGERVVGGEDVVGKTLDLDTVCPVLKDLGYCPFGWRCRFLGAHVKRVAAAVDGEKEKEAGPEKRMGEWQVENWVQSEVENGWKQKETNWPEHEVLNALRRSTASFPFSEAYLKKVDPDKPFTLQNKKPTKQQPHKRKNNVLDEEEAANGPTGIPSAGDDEENAMNATENERNEEKGKVYGETEAIDVPLRPEEKRRLNWEGGRYLAPLTTVGNLPFRRLCVDYGATITVSEMALAQPLVYGAKEEWALVRRHESEKMFGVQVAGGFPNRMVPAAEVIANTIGKGGGVDFVDVNMGCPIDLVFNQGAGSALMDSPGRLGKLLVGMNRALGDIPLTVKFRTGVAHGKPNAHKLIPRFVTEWGAGALTIHGRSRQQRYSKPADWEYIKTCVTALRESVADANLPPVPIFGNGDCFSAASYYEEMDRSGVDGVMVARGALIKPWIFTEIKERREWDISAVERLEGIKKFAEFGLSHWGSDTQGVNTTRRFLCEALSFQHRYIPIGLLERLPAKLNERPPAYRGRNELETLLASPFAGDWVKISEMFLGKVDEGFSFVPKHKSNAYGGEEAQG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SARS_STAAC
Sequence: MKYNNHDKIRDFIIIEAYMFRFKKKVKPEVDMTIKEFILLTYLFHQQENTLPFKKIVSDLCYKQSDLVQHIKVLVKHSYISKVRSKIDERNTYISISEEQREKIAERVTLFDQIIKQFNLADQSESQMIPKDSKEFLNLMMYTMYFKNIIKKHLTLSFVEFTILAIITSQNKNIVLLKDLIETIHHKYPQTVRALNNLKKQGYLIKERSTEDERKILIHMDDAQQDHAEQLLAQVNQLLADKDHLHLVFE
What is the function of this protein?
Transcriptional regulator that controls expression of some virulence factors in a cell density-dependent manner (By similarity).  Acts as a transcriptional activator of the gene encoding protein A (spa).
What are the official names of this protein?
HTH-type transcriptional regulator SarS, Staphylococcal accessory regulator S.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC11_EMENI
Sequence: MLSFLSSNLSNTRQSIAQVLNFALVLSTAFMLWKGLSVVTASSSPIVVVLSGSMEPAFQRGDLLFLWNRSPRAEVGEIVVYNVKGKDIPIVHRVVRTFPEVEGKKEKTVKEVTVSTPTPPNMLLTKGDNNLADDTELYARGQEFLHRKEDIVGSVRGYMPMVGYVTIMLSEHPWLKSVLLGIMGLMVILQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit sec11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: HSLV_MYXXA
Sequence: MFHGTTILCVRRDGKVAIASDGQVSLEKTVMKNTAKKVRRLGEGQVLAGFAGSTADAFTLFERFEAKLKEHQKNMARACVELGKDWRTDRFLRRLEALLIVADKEKTFILSGAGDVIEPDYGIAAVGSGGPYAFAAARALMAHTQMSARDVVHQSLTIAGEIDIYTNANISIEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLCL1_HUMAN
Sequence: MAEGAAGREDPAPPDAAGGEDDPRVGPDAAGDCVTAASGGRMRDRRSGVALPGAAGTPADSEAGLLEAARATPRRSSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSDNTPSVSLVMKDSFPYLEPLGAIPDVQKKMLTAYDLMIQESRFLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKATESFAWNITVLKGQGDLLKNAKNEAIENMKQIQLACLSCGLSKAPSSSAEAKSKRSLEAIEEKESSEENGKL
What is the function of this protein?
Involved in an inositol phospholipid-based intracellular signaling cascade.  Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol.  Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity).  Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition.  Its aberrant expression could contribute to the genesis and progression of lung carcinoma.  Acts as an inhibitor of PPP1C.
What are the official names of this protein?
Inactive phospholipase C-like protein 1, PLC-L1, Phospholipase C-deleted in lung carcinoma, Phospholipase C-related but catalytically inactive protein, PRIP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_PYRAE
Sequence: MVRLAIVVAEFNYDITQLMLQKAVEHAKFLGAEITYIVKTPGVYDIPMILKELVAKEEVDAVATLGAVIQGATKHDELVATQAARKILDIAVESGKPITLGIIGHGANRIQALERVEEYARRAVEAAVKMARRKKALREAKYNGSTVYID
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: KAD_PHOLL
Sequence: MRIILLGAPGAGKGTQAQFIVEKYGIPQISTGDMLRSAVKAGTELGLKAKALMDHGKLVTDELVIALVKERIKQDDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIIERIIGRRIHAPSGRVYHIKFNPPVVENKDDVTGEELTVRKDDHEDIVRKRLVEYHQQTAPLVSYYQKEAEADYTKYFGIDGTRKVSEISEELSKILD
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_VIBVU
Sequence: MKAVVLGSGVVGLMSAWYLQKAGYQVTVVDRQARSAEETSFANAGQISYGYSSPWAAPGIPQKALRWLMEEHAPLKIKPSLDPQLLKWATQMLANCQLSRYQVNKARMLAIANHSRECLSQLRQEHDIEYQGRQQGTLQVFRTQKQLIAIEKDIALLEQSGTRYQRMSVDECIKQEPGLAAVSHKLTGGLYLPDDETGDCYLFCQQMTELAQQQGVTFLFNTNVKKVNTQGNQVVSVSTDAGELQADVYVVAMGSYSTALLAKLGITIPVYPVKGYSLTVPITDESQAPVSTVMDETYKVALTRFDDRIRVAGTAELAGFDPAIPEKRKATISMVVNDLFPHSGDFAKAEFWTGFRPMTPDGTPLIGKTPLKNLYTNTGHGTLGWTMACGSGHLLSQIITGEQSENPAGLDLFRYAS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: GLGB_COREF
Sequence: MTPASANDLLIPEEDLNRLRHCHHHNPHGFYGWHATDDGSVIRTRQIGAEKVELVLGDTQIVMNPIGDDIFAIKLGNREAFDYRLRVTWPGQDPVVTADPYIFLPTLGEMDTYLISEGRHERLWDVLGANVKTYETTLGQVRGTAFAVWAPNAIGVAVIGGFNGWNASQHAMRSLGGSGIWELFIPNIGPGEVYKFAIQTREGHRRDKADPMARLAELPPATGSIVVESDYQWQDSEWMDKRAEIDTATTPMSVYEVHLGSWRWGRSYAELATELVDYVADLGYTHVEFMPVAEHPFGGSWGYQVSGYYAPTSRWGSPDELRKLIDAFHARGIGVIIDWVPAHFPKDDWALARFDGQALYEHPDWRRGEQKDWGTYVFNFGRSEVRNFLVANALYWLEEFHVDGLRVDAVASMLYLDYSREHGEWEPNVYGGRENLEAVQFLQEMNATVQRVHPGALTIAEESTSWPGVTAPTWDGGLGFSLKWNMGWMNDTLEYFSKDPIHRSFHHNELTFSLVYAFSERFVLPISHDEVVHGKGSLWNRMPGDTWNKAAGMRTLLAYMWAHPGKKLLFMGQEIGQRDEWSEAHELPWGVVEGWQGEYHEGISDLVRELNSTYKEVTALHQRDFSGEGFTWNKADDASNNILVFTRHGDDGSQALCVFNLSGTSQPEYQIGVSGGGSWRLVLNTDDEQYHGANNPLPETIEAEKIDRDGFPYTTTLHSPAMSAQFYVWEG
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: NUSB_BRUA2
Sequence: MNSIPEGRPTPNLPRTANKRGVARLAAVQALFQMDVAGTGVMEVVAEYEAFRLGKEVDGTQYLDADPQWFRAIVAGVVEDQLKLDPMIHQALTEDWPLSRLDSTLRAILRAGAWELKARKDVPTAVIVSEYVDIAKAFYTEDEPKLVNAVLDRLALVIRGESRGAKPRHKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RECA_BORT9
Sequence: MSKLKDKIDDSLNDRLNREKAIELARIQIEKDFGKGSLIKMGESPVGKGIESISSGSILLDEAIGVGGYPRGRIIEIFGPESSGKTTLTLQAISEVQKNGGIAAFIDAEHALDPVYAKALGVNIDELWLSQPDTGEQALEIAEYLIRSGGVDLIVVDSVAALTPQAEIDGEMGDCQIGLQARLMSKALRKITGILSKSKTCIMFINQLRMKIGVMFGNPETTTGGNALKFYSSLRLEVRKIEQVTGSSADDVVGNKVRVKVVKNKVAPPFRKIELVIYFGKGISREASILDASIKYKLIQKIGSWYSIGDDKLGQGRESAIIYLIKEKELTNELEIKLRKIIFEGLSPDSIEIGPPNVKKDKE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFGH_HAEIN
Sequence: MKLIEQHQIFGGSQQVWAHNAQTLQCEMKFAVYLPNNPENRPLGVIYWLSGLTCTEQNFITKSGFQRYAAEHQVIVVAPDTSPRGEQVPNDAAYDLGQGAGFYLNATEQPWATNYQMYDYILNELPDLIEANFPTNGKRSIMGHSMGGHGALVLALRNRERYQSVSAFSPILSPSLVPWGEKAFSAYLGEDREKWQQYDASSLIQQGYKVQGMRIDQGLEDEFLPTQLRTEDFIETCRVANQPVDVRFHKGYDHSYYFIASFIGEHIAYHAEFLK
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: NORD_BRUME
Sequence: MLDFLELEETVGRAWHRLIGKTGSWPQYPDHAVQLVDIRQRLAICFRGFGGDIAVQIAPARARTSTHRLGLRQRMALGEEKLAQPLRDEATLMLPPEIALFPDRQLNYDLYVWLVGYMAVMPMDADALPEDALRRDLAALQIAEQTVERACRAFPGLKPRYKRLCAAILAERPKRPLHRLEQQVEARILSLLKQGADLPDDALPTIFPHRGPAGYLPALPVPLWPGLMKREEVAPRTGEDEPVRNSQSEGAETGRQIAQRERQDPRHADRSPFILNRFEKILAMAEMVSVDRPSDGSDEQNAKSADELDDLTLGERKGRPAARFRFDLDLPPEAVDRSLLTAELTYPEWDYRKGAYLPNHCAVLAAPVQEKEKPLELDAAAQSLVRRVRRQFEILRPGREVLRAQLDGTDLDLDAVVRSRCDLAAGGQGSDRVHLMSRPQANDLAVTLLVDVSLSTDAWVDNRRVLDVEKEALLVLANGIAACGDRCSILTFTSRRRSWVRVETVKDFDESFGPTVEHRIAALKPGFYTRMGAAMRHATAKLAEQPNRKKLLLLLTDGKPNDVDHYEGRFALEDSRRAAGEVRAKGVNVFAVTVDREASAYLPALFGRGGYALVANLAKLPVALPAIYRMLAG
What is the function of this protein?
Part of the operon norEFCBQD encoding nitric oxide reductase.  Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection (By similarity).
What are the official names of this protein?
Protein NorD.
Protein: GNT14_DICDI
Sequence: MFGFKTTKNKKRVRLLVVAIGVMIFFMCLSNFSSIQSRQSSSTDTPLQQNGKHQVIRVLETQPSININNSENNINNENINNNQNNNPNNNMDNNNKNNNKNNNIDNNNNKNNNNNDNIDNNINNNNNNNNNNNNINNNNNINNNNNIDNTDNNINNNINNNNININNNNKPSYKKPEKKPPLSSSQIFFNSLPPHIQKQVVIREKSNYAQALQYDSYGIVPAKDFFDGLDAVFETKPNYKISTVRKLFNIENLNSNNNNNNNNNNNNNNNNNNNNNYDINNYNNINIKEDDKFENKNYQNGDKNIMYSDYKGIDYGNNNNIEEIERIKEELKIELEKENVNDIFKYRVTIVTQTTVDRLYKVAAMAERWRSPISVSLFIKSQGDIDKLEKAISANKILATFADFHLFYHNNTRYPVNNLRNLAIRNALTEHVLLLDVDFIPPSHLHDHIAHYINLNYLNQDDSLNAFVIPSFSSNLQPKDIPDSKFEFIEMLTKNKIEPSNLKVCPKCHSPTDYTRWMTSTEPYAIEYHWIYEPFLVYNRSQTLPFDERFKGYGFDKNSQIFGMAAQGFTFSVLPEAYIVHINHPTSRWDGPSLDDQQWDSLRVVCDLLPEIRKRYAKGYKVDRLFDEPTTENCYSNDHW
What are the official names of this protein?
Glycosyltransferase-like protein gnt14.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family. Highly divergent.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: NCAP_I86A3
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYVQMCTELKLNDHEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRKDGKWMRELILHDKEEIMRIWRQANNGEDATAGLTHMMIWHSNLNDTTYQRTRALVRAGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVREGRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEKEGYSLVGIDPFKLLQNSQIFSLIRPKENPAHKSQLVWMACHSAAFEDLRVLNFIRGTKVIPRGQLATRGVQIASNENMETIDSSTLELRSRYWAIRTRSGGNTSQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTERRTSDMRTEIIRMMENARSEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEFDS
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: HFQ_NITMU
Sequence: MSAKGQLLQDPFLNTLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLKNTVTQMVYKHAISTVVPARAVNIPFEAPPISDA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: MUTS_ECOSM
Sequence: MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRALLENVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIAPGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: C6A17_DROME
Sequence: MLLLALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLNIQEAEDFYTKIVRETIDYRLRTKEKRNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNILISAENGIHLKVEKLAK
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 6a17, CYPVIA17.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: LGT_SALPC
Sequence: MTSSYLHFPDFDPVIFSIGPVALHWYGLMYLVGFVFAMWLAVRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPLFLDNPLYLFRVWDGGMSFHGGLIGVILVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPDFRFAMLFPGSRAEDIALLPSHPQWQPIFDTYGVLPRHPSQLYELALEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIIAGAIMMVWAYRRRPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL34_THEAQ
Sequence: MKRTWQPNRRKRAKTHGFRARMKTPGGRNVLKRRRRKGRWRLTPKVSG
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.