PharMolix/UniProtQA huggingface dataset:
Protein: THIO_MYCGA
Sequence: MKHITNKAELDQLLSTNKKVVVDFYANWCGPCKILGPIFEEVAQDKKDWTFVKVDVDQANEISSEYEIRSIPTVIFFQDGKMADKRIGFIPKNELKELLK
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: PANB_BRUSU
Sequence: MSAPVTRKRLTPKVIQAMKGECPIVSLTAYTTPVARLLDPHCDLLLVGDSLGMVLYGMESTLAVTLDMMIMHGQAVMRGTSHACVIVDMPFGSYQESKEQAFRNAARVMQETGCDGVKLEGGEEMAETVAFLVRRGIPVFGHVGLMPQQVNTVGGFRSLGRGDDEAGKIRRDAQAIAQAGAFAVVIEGTVEPLAREITALIDIPTVGIGASSACDGQVLVSDDMLGLFQDFTPRFVKRFAHLAPQVSQAAEAYAEEVRARRFPGPEHVFGAKPGA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOMPP_CHLPS
Sequence: MKKLLKSALLFAAAGSALSLQALPVGNPAEPSLLIDGTMWEGASGDPCDPCATWCDAISIRAGFYGDYVFDRILKVDVNKTISGMAAAPTAASGTASNTTVAADRSNFAYGKHLQDAEWCTNAAYLALNIWDRFDVFCTLGASNGYFKASSDAFNLVGLIGLAGTDFANQRPNVEISQGIVELYTDTAFSWSVGARGALWECGCATLGAEFQYAQSNPKIEMLNVTSSPAQFMIHKPRGYKGTAANFPLPVAAGTATATDTKSATVKYHEWQVGLALSYRLNMLVPYIGVNWSRATFDADTIRIAQPKLASAILNLTTWNPTLLGVATTLDTSNKYADFMQIVSMQINKMKSRKACGIAVGATLIDADKWSITGEARLIDERAAHINAQFRF
What is the function of this protein?
Permits diffusion of specific solutes through the outer membrane.
What are the official names of this protein?
Major outer membrane porin, MOMP.
What is the protein family that this protein belongs to?
Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: NADE_STRPJ
Sequence: MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFVLGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQPDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGTDHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDKPGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: TATD_ECOLI
Sequence: MFDIGVNLTSSQFAKDRDDVVACAFDAGVNGLLITGTNLRESQQAQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFSTPEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREEMQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSSRRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WOX3_ORYSJ
Sequence: MPQTPSTRWCPTPEQLMILEEMYRSGVRTPNAAEIQQITAHLAYYGRIEGKNVFYWFQNHKARERQRLRRRLCARHQQQPSPPSSTVPPAPTAAAAGAVVQVHPAVMQLHHHHHHHHPYAAAAAAQSHHLQQQQQQQAEWPAAVDYCSTASASASATAADMAIPPCCRPLKTLELFPTKSTSGGLKEDCCSSSKSSSCSTSTN
What is the function of this protein?
Transcription factor which may be involved in developmental processes.  Seems to act as repressor of YAB5.
What are the official names of this protein?
WUSCHEL-related homeobox 3, OsNS, OsWOX3.
What is the protein family that this protein belongs to?
Belongs to the WUS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BAMA_ECO45
Sequence: MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALLSMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGNLAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKTVKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFKTDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDDHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNYDPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWDMGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: TSG13_HUMAN
Sequence: MSQKRQTKFQNGKSKTSENSSAKREKGMVVNSKEISDAVGQSKFVLENLRHYTVHPNLAQYYKPLKATALQKFLAQNRKNTSFMLKVTQYDQDKTLLIMTNNPPPCSITQQDKESASKYFSKELLLKVMESHHQHKPTENLWLPRMPQKKKLRSKLKPIFPLILSDDPTSKREQWFRFSTDNDFKSEGKYSKVYALRTQKKMYPQLTFAPVHERDMRKDASKKSASERPISKVIREPLTLASLLEDMPTRTAPGESAFRNGRAPQWIIKKATVIG
What are the official names of this protein?
Testis-specific gene 13 protein.
Protein: GLNA_ARCFU
Sequence: MVRRLRGDCMEEVERAKAVLKENNVRQVLCAFADVRGYLQMFSIPAREFVDGSAFENGIGFDGSSVRGFRTIEKSDMVWMPDASSLKIIPWIDDPIQKSAIMFGNVYEAWGTEIADCDPRGYVAKRYEDMLKSEGMSAIFGPEIEFFLFEGVDFTRLSWDMWVSPNGGAGDSWGPPRIMPISSELESGYMIRPKEGYFRPPPEDTTVEYRNELVYYLEQLGIDIEYHHHEVATAGQVELDFKPKQLVDVGDAFYLYKFAAKNIAAMHGLYATFMPKPLYLDNASGMHTHQSLWKGEPFSGEAVFADPDDEYMLSQKARYYIGGLLEHAKALTALCAPTVNSYKRLVPGFEAPIYICWSPRNRSALVRVPMYVKKPSAIRVEYRGVDPSCNPYLAITAQLAAGLDGIKKKIDPGDPLLEDVYELTPAQKRELGVGELPTTLRDAIDHLASDELMQEVLGSHIFDAFMELKIDEWNQYCLYITPWEFMKYFDI
What is the function of this protein?
Probably involved in nitrogen metabolism via ammonium assimilation.  Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Beta-glutamate is a much poorer substrate than alpha-glutamate.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_BLOPB
Sequence: MNIQKFLLKKIHRALLAITNESFFHLIQVQQSTKRKFGNYQINGLIAISKKLNIPIEEFAKKFIQFINLNDVAHTIKIEKPGFINIFLNTKWISNQINNIFSASHLGITPATPKTIVIDYSGPNVAKEMHVGHLRSTVIGDSIARVLSFLGHNVIRANHIGDWGTQFGMLIAYIEKNAQTRFLLNKTIQLSTLEHFYREAKKKYDIDPDFAELSRNYVLKLQKGDKHYRQIWKYLVDISILNNQDIYVRLNINLKKSDIIGESFYNDMLPDIVSDLKNKGLAVTSNGATVVFLENYHNKLGTPFGVIIQKKDGAYLYSTTDIACIKYRCKVLHADRIIYYIDSRQKQHLIQAWEIADKAGYIEKSVLLEHHMCGMLLGKDGKPFKTRAGNALKLKTLLDEALERARCLILSKNPNLKYTEINKLAHIISIGAIKYSELSKNRITDYIFDWNNMLNFEGNTAPYVQYACTRIFAIFKRSKQPNFQLKKNDIQLETEEEILLAICLLQFEEMIVAVSNQGAPHILCSYLYKLSVLFSSFYENCPIIKAHNTHIKYSRLKLALITMRTLKTGLNLLGIKTVRYM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APBC_SACS2
Sequence: MSSNPFRIQNPQPQPQRQPRDLRKVNQQVQAVDLKVQMKMKNIKYKIGVVSGKGGVGKSFVSSNLAMAIAASGRKVGIVDVDFHGPSVPKMLGVRGQMLTADDKGINPVIGPFGIKVVSIDFLLPRDDTPVVWRGAIKHSAIKQFLGDVNWGELDYLIIDMPPGTGDEALSIAQLVPGITGFVIVTIPSEVSTLAVKKSINFARTVNTKILGVVENMSHFVCPSDGKVYYIFGEGKGKKMAEEMGVDLLGQVPLDPSIAEANDAGEPFFLKHPDSPTSKEFLNIADKVIKIVESNQ
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: LSPA_XYLFA
Sequence: MTRPTHPNALIWLLLSIAIIALDQATKAWVLTSLPEYIPVPVIHGFWNWYRSYNTGAAFSFLSDAGGWQMWLFIALALGISGLLTFWLSRTPRREWRSALPYALIIGGGIGNVIDRFLHGHVVDFIQWYVGSHYWPSFNLADSAIVAGAIGIGLLSLFDSKHSPKTP
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSIC_ECOL6
Sequence: MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEADAQVIELVRQQLGLDQPLYHQFWHYISNAVQGDLGLSMVSRRPVADEIASRFMPTLWLTITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEILLFSLEFILINLVVDVLYAAINPAIRYK
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURA_MYXXD
Sequence: MPNVVVIGAQWGDEGKGKVVDLLTEHAQVVVRFQGGNNAGHTLVVGGQKTVLHLIPSGILHPGKTCVIGNGVVVDPAVLVGEIDALKVRGFLKDDAQLLISDNAHVIFPWHKLLDSFREKARGGSAIGTTGRGIGPAYEDKVARRGIRVRDLLNADRLRTRIEARLPAALDELKDLCAQAGDPVPQLEVPQILAEFTGLGERLKPFVHDASLYLSGQVRRGARILFEGAQGTLLDVDHGTYPFVTSSNCVAGNAAVGSGLGPTAIDKVMGISKAYTTRVGGGPFPTELHDAIGDQLRKMGDEFGTTTGRPRRCGWLDGVVLRYASRVNGLWGMALTKLDVLSGLKTLQICTAYELDGQKVMELPGDYEDLARVKPIYETLQGWDEQIAGVRTFDELPENAKRYVRRVEEVSGVPVVCVSVGADRGETVLLQNPFRS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_NEIGO
Sequence: VDRPFKEVEANEGYRLSIDLAEQTLTTPGGETFTFDITEHRKHCLLNGLDEIGLTLQHADKIKAFEEKRRQSQPWLFNG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: DAPB_TRIEI
Sequence: MISQTSTPVIVCGAAGKMGREVIKTVANASDMTLLGAIECQPEYIGQDIGELIGSGPLEVPILNDLQGILVMAAQEKQPAVMVDFTHPDSVYENVRSAIAYGVRPVVGTTGLSQEQIQDLAEFAEKASIGTLIIPNFSIGMVLLQQAAIAASKHFDHVEIIELHHNQKADAPSGTAIKTAQMLSELGKTYNVPNVEETEKIEGARGCLAEEGIRIHSVRLPGLIAHQEVIFGGPGQIYTLRHDTTDRSCYMPGVLLAIRKVQSLTKLIYGLEKIL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRA_MYCTO
Sequence: MTEQPPPGGSYPPPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPPPPGGGAYPPPPPSAGGYAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLVGIGWVIMLVTQTSSCVTSISEYDVGQFCVSQPSMIGQLVQWLLSVGGLAYLVWNYGYRQGTIGSSIGKSVLKFKVVSETTGQPIGFGMSVVRQLAHFIDAIICFVGFLFPLWDAKRQTLADKIMTTVCVPI
What are the official names of this protein?
Proline-rich antigen homolog, Pra.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial Pra family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WASC3_DICDI
Sequence: MQVYVDYRDVNSISNKKTLAYVNNFVINTTQFLNRFNYLCEQKLCDISNHLQKLEITMSLLEIKLGSIDGLESLPSSANVPVHNTQPTTQQNTPPPPTAAATTSSNIPPPPPPPPPPMTGVPPPPPPPPPPPISKSNIPPPPATQQNTQESDDDDEDNNNNDKNNNNRDDEDDDDETSSQAPPPPPMPTLPSSQSLMDNLAAVLAMKKQQRNPQPPQPQPQSPSPQPPPPPTTTSSIPVPPPPFSGANNNSDDDDDDDEGPSLSIPAPPSMMVMSGNNNSNSNSYSNNNNNKDDDDDDDDDDDDDDNSISIPKPPQMDDIMIPAPPTDLFIPAPPSIRNYDDADDDDDDDDESW
What are the official names of this protein?
WASH complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the CCDC53 family.
Protein: RSMJ_SALPC
Sequence: MQICLMDETGATDGALSVLAARWGLEHDEDNPMALVLTPQHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLTRGYADADIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVKRPDYAPPLADVATPNAVVTKGHRFDIYAGTPLTE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERR_PSEFL
Sequence: MENNLENLTIGVFAKAAGVNVETIRFYQRKGLLLEPDKPYGSIRRYGEADVTRVRFVKSAQRLGFSLDEIAELLRLEDGTHCEEASSLAEHKLKDVREKMADLARMEAVLSELVCACHARRGNVSCPLIASLQGGASLAGSAMP
What is the function of this protein?
Mediates the mercuric-dependent induction of mercury resistance operon.  In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site (By similarity).
What are the official names of this protein?
Mercuric resistance operon regulatory protein.
Protein: PRS55_HUMAN
Sequence: MLLFSVLLLLSLVTGTQLGPRTPLPEAGVAILGRARGAHRPQPPHPPSPVSECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQLEGRPFNAEKRRTSVKQKPMGSPVSGVPEPGSPRSWLLLCPLSHVLFRAILY
What is the function of this protein?
Probable serine protease, which plays a crucial role in the fertility of male mice including sperm migration and sperm-egg interaction.
What are the official names of this protein?
Serine protease 55, Testis serine protease 1, T-SP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm, cytosol. Note=Mainly found in the membrane part of the cells and only in small amounts in the cytosol. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytosol. Note=Present primarily in the cytosol and only in minor amounts in the membrane fraction.
Protein: LEPA_RICFE
Sequence: MNNQKYIRNFSIIAHIDHGKSTLADRLIEHCGGLQAREMSQQVLDSMDIEKERGITIKAQTVRLVYKAKDGNTYYLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDSTQGVEAQTLANVYQAIENDHEIVPVLNKIDLPASEPEQVKQQIKDIIGIDASEAVLISAKSGIGIDLVLEAIVNKLPPPKESSSDILKALLVDSWYDPYLGVVILVRIIDGTLRKNIRIKMMATNSVYTVENVGYFTPKKHISDVLHAGEIGFFTASIKQVADCKVGDTITDEKKPCEQALPGFKPNLPVVFCGLYPTDSAEFEHLKDSLAKLRLNDASFEYEMESSSALGVGFRCGFLGLLHLEIIQERLSREFDLDLITTAPSVVYKIHMRDGESLEIHNPADLSDLQKIESMEEPWIKATIMVPDEFLGAVLSLCTEKRGVQLDHSYIANRAKIIYKLPLNEIVYDFYDRLKSCSKGYASFEWQMDVYEPSELVKLGILVNGEEVDALSTIVHRSRAEQRGRALCVRLKDLIPRQQIDIAIQASIGSRIIARETIKALRKDVLSKCYGGDISRKRKLLEKQKAGKKRMRQYGNIEIPQSAFIAALKIGDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SODM_CRYNH
Sequence: MITAITRTALPRATLRTSLATMSTIRAKHTLPPLPYAYDALEPSISAEIMNLHHTKHHQTYVNGLNAAEESLQKASADGDFKTAISLQPALKFNGGGHINHSLFWKNLAPTGSAQVKVPTSGVFYDQVQADFGGFENLKKEMNAKTAAIQGSGWGWLGYNKATKKLEIVTTPNQDPLLSHVPIIGIDIWEHAFYLQYKNVKPDYLNAIWNVINYEEAESRLKAAQ
What is the function of this protein?
Destroys cytoplasmic radicals produced in low copper environments; a condition which inactivates the cytoplasmic copper-dependent superoxide dismutase SOD1.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. Note=Localizes to the mitochondrion both in copper-replete and copper-limiting conditions. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: SNP23_MOUSE
Sequence: MDNLSPEEVQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCICPCNRTKNFESGKNYKATWGDGGDNSPSNVVSKQPSRITNGQPQQTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADTNKNRIDIANTRAKKLIDS
What is the function of this protein?
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
What are the official names of this protein?
Synaptosomal-associated protein 23, SNAP-23, Syndet, Vesicle-membrane fusion protein SNAP-23.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Synapse, synaptosome. Note=Mainly localized to the plasma membrane.
Protein: MIAB_HAEDU
Sequence: MAKLHITTWGCQMNEYDSSKMADLLNSTHGLELTDKPEEADILLLNTCSIREKAQEKVFSQLGRWKNWKKDKPDLIIGVGGCVASQEGEHIRERAPFVDIVFGPQTLHRLPEMINQIRSGDRAVVDISFPEIEKFDRLPEPKAEGPTAFVSIMEGCNKYCSFCVVPYTRGEEVSRPVDDVLFEIAQLAEQGVREVNLLGQNVNAYRGETFDGGICTFAELLRLVAAIDGIDRLRYTTSHPIEFTDDIIEVYRDTPELVSFLHLPIQSGADRVLTMMKRNHTALEYKAIIRKLRAVRPNIQISSDFIVGFPGETAEDFEQTMKIIEQVNFDMSFSFIYSARPGTPASDLPDDVSENEKKDRLAHLQQRINHQAMQFSRLMLGTEQRILVEGPSKKDIMELTGRTETNRVVNFIGTPNMIGKFVDIKITDVYSNSLRGEVIRTEDQMGLRIVESASSVIARTRKEDDLGVGKYAVNL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_NITVU
Sequence: MAVQAYRSLKKYETFSYLPQMTPEQVRRQIAHAIAQGWNPAVEHTEKGTPAKASYWYMWKLPLFGEQSVDAVVAEIEACHREFPDQMVRFVAYDNYAQSQGMAFVVYR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
Protein: METAS_SERP5
Sequence: MPIRVPDELPAVSFLRNENVFVMASSRAKTQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQIDIQLLRIDSRESKNTPAEHLNNFYCDFEDIQDENFDGLIVTGAPLGLVDFCDVAYWPQIERVIDWAKNHVTSTLFVCWAVQAALNILYGIPKMTREVKLSGVYQHQTLQQHALLTRGFDETFLAPHSRYADFPTEIIRQYTDLDILAESEQTGAYLFASKDKRLAFVTGHPEYDALTLAGEYCRDNDAGLNPVVPLNYFPDDNPELTPKASWRSHGHLLFANWLNYYVYQITPYDLRHMNPTLE
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT13_DROPS
Sequence: MFERNQKTIFVLDHTRYFSIASEEYISMDFLKGKPSAHSSAGGSSQFSKSLWTCACESSIEYCRVVWDLFPGKKHVRFIVSDTAAHIVNTWSASTQNMSHVMNAMVMVGVPSRSMPQSSDYSVIHGLRAAIEALAEPTDEQSQAMASGVPDDLILNEGRVICITSARDNTSMKSLEDIFNTVLIQQNVLSATPPKKGLGINHCHLVILNIVPLGIDSMVTNRNLLEISPLLDVEIHTVGAPDISYKLTHLILDHYDLASTTVTNIPMKEEQNANSSANYDVEILHSRRAHSITCGPDFSLPTSIKQGATYETVTLKWCTPRGCGSADLQPCLGQFLVTPVDVTSRPSSCLINFLLNGRSVLLEMPRKTGSKATSHMLSARGGEIFIHSLCITRSCMDEAPSIADGPGGRVNDYRTSELGQLMKMSRMVPLKSRDPAAPNLPRRLPRYFPLTTTSTVLFHLQRHLSWLPHFLHLLVKEMDKQDEVRCQQHIHELYKSASRGDVLPFTHTNGARLKPHKAKDQYRLLYRELEQLIQLNASTVHHKNLLESLQTLRAAYGDAPSKSEAGTANLRSFTESPLSPERLEAMSNVSISSSTNSNSLLKASKRRMSNCGTRSLLDIISSAERSQSNKRLDFSGRICTPIGQIAKLYPDFGNKEKDAAAAAAASGVGVAPKE
What is the function of this protein?
Plays a role as a regulator of spermatogenesis.  Crucial regulator of the mitotic cell cycle and development.  Required for the correct dynein-dynactin perinuclear localization important for nucleus-centrosome coupling that occur upon meiotic progression of primary spermatocytes.  Crucial regulator of the mitotic cell cycle and development.  Plays a role in sperm motility and fertility.  May have a role in the PNG/PLU/GNU pathway (By similarity).
What are the official names of this protein?
Protein asunder, Cell cycle regulator Mat89Bb, Set apart in position or space protein.
What is the protein family that this protein belongs to?
Belongs to the asunder family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Colocalizes with dynein-dynactin on the nuclear surface at the meiotic G2/prophase transition in primary spermatocytes. Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M.
Protein: ISPE_SHIF8
Sequence: MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.