PharMolix/UniProtQA huggingface dataset:
Protein: OSTC2_DIPSG
Sequence: MKTLVLLSICALLSVCWSMGAVEPEVVVDTVADTTADAAPADPAAAAAPSSSSSESSESSESSESSESSESSESSESSESNSSSASDSNSSSDSSASDSNSSSDSSSSSSSSSSSSSSSSSSSESTESSESSESSSSSSSSSSSSSSSSSSSSSESSSSESNSADSSASDSPSSSSSSSSSSSSESASDEAAKVVVKRDLASVLLRRRRAAPGGDLTPLQLESLREVCELNIACDEMAETAGIVAAYVAYYGPVPF
What is the function of this protein?
Binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin 2, DsaOC2, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAF4_DEBHA
Sequence: MSDVSGGESSSHKRNVDSAANENDDMQNKRQKTEELGGHDDQLNDIFNDPLPGFGGSESNSTPYNDNAQEGELGPENFDATLPKEGDPLDIDFDNLPTNFLEAEQATNANNGSQVDTPSGPGSVPNMSVTTNSASMSASPNNTPRPTPLSKTNSRSETPVGNSSRATYDGTNLKQEFGINGLSNKQEALNRYSQMPPTNRMNHLAPQPQGIQGLNTSSIDRIPSTSTSNKEQLHTNDPSKLNDALAAAGVDIQHEEELLMQQHLNRSSRFPSAQQPPRQRFAQTSLFSPYHVAAFMQRVARENGVMQNFYQDAELLELMSTSCENWLSNIITKTIILSRHRRRGIPTITNTKQNKKTASSSASMSNPASRSELSKELRNLAAKQKEMEERRVSKRMALGLEKDGTDPGNGDPANGKAGAEETLHRAANATAAMMTMNPGRKKYSWMTANAGSGGGDDSKVASEKDGKSKQSSIIAARGDNGLRFREIRSGNSVTMKDLLGALEDERMGTEKAVLKGYAKLKD
What is the function of this protein?
Functions as a component of the DNA-binding general transcription factor complex TFIID.  Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation.  TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (By similarity).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 4, TBP-associated factor 4.
What is the protein family that this protein belongs to?
Belongs to the TAF4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GET1_PARBP
Sequence: MPSLLISVLFLHIAIYIINTIAASTIDSLLWLIYMKLPTSASCIAREQHQMKLEVVQLKREMNATSSQDEFAKWAKLRRRHDKALEEYEVKNKQFSRFKSFFDVAVKALRWAGTSGLIVFLQFWFSKTPIFTLPPSWIPWQVEWVLSFPRAPMGTVSIQVWGGACAVVVALIGEAIGATVRYLYASKDSMEAIKVGAGAVEKEKKRQ
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein GET1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MTLD_BUCBP
Sequence: MNALHFGAGNIGRGFIGPLLLKSGFNLTFVDNNQAIVDAINRHQKYDITVVGNNFSYITTVKKVKAIYINDPNIYFKIAKINVITISVGVHAINSLVVFFEKLIRYKIETNDFVFLTIIACENVFRCASKLKENIKILLPGIYHKYLDKNISFVDSVVDKIVCPNDKNNSDDINLSVKVEKFSEWIVDCTQFKHDRPNIIGMIYSNHLDAFFERKLFTLNTGHAIAAYLGLLIGYKNIYQAILDPLIFNIVYGAMKESGMVLIRKYNFFTDSEHKNYILKILSRFKNIYLTDSLKRVGRNPLQKLKKDDRLISPLIDTIKYNLPNANLMKGIAAALCYIDEKDIEAKKLRNMIINKGIKYVLSKISSLDSSLLIISEISIYFNIFMKVNI
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: SUCC_HALSA
Sequence: MKLHEYQAKEVFADAGIPTPESALATSVDEAVEVADALDYPVAVKAQVHVGGRGKAGGIKLAENTAEAREAAESILGMDLKGYTVDRVLVEEAVDFTNELYVGVTMDRSEGAPVVMVSERGGVDIESVAEEAPEDIVREHVDPSFGLQAYQARNAVYDAGIEQDVAGDVAKIVQGVYDLWADSDATEVEINPVMVTSERDVVAADAVMKLDEDALFRQPAFADMEEDAAEDDLEAKANEYGFDYVRLDGNTGIIGNGAGLVMTTLDLVDYYGGQPANFLDIGGGAKADRVANALDMVFSDENVDSVVFNIFGGITRGDEVAKGINSALEQFDEIPTPVVVRLAGTNAAEGREILNDDLVTVEETLEGAVQRAVEYADEEDIQ
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PRR5L_MOUSE
Sequence: MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPVLSELPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKLCEGDNRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDVLLLAQSKLPSSVIQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLSISGDRSCSGPTYSLARRHSRVRPKVTVLNYASLMTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEEAGGEDKHLLLPPSFPPPHRQCSSEPSILDSPDELELEDVASGSQEDSELNCASLS
What is the function of this protein?
Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton (By similarity).  Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration (PubMed:22609986).  Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress.  Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress.
What are the official names of this protein?
Proline-rich protein 5-like, Protein observed with Rictor-2, Protor-2.
What is the protein family that this protein belongs to?
Belongs to the PROTOR family.
Protein: CSRA_SYNAS
Sequence: MLILTRKLGESIVIGDQIQITLLDIKGKHVRIGVNAPKGIAVHRGEVYEMIQDENKKAFESDVKNSEMLSALWAQVKIL
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_SHELP
Sequence: MPIILGVDPGSRITGYGVIQCQGRQQIYLGSGCIRTQSDDLPSRLKVIFDGISEIIRQYQPDEFAIERVFLAKNADSALKLGQARGAAIVAATNAQLPVAEYSATQIKNAVVGTGRAQKSQVQHMVQQILKLPAAPQADAADALGVALCHFHTYQSLIAMGGKASVRTYGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ACTT1_HUMAN
Sequence: MFNPHALDVPAVIFDNGSGLCKAGLSGEIGPRHVISSVLGHCKFNVPLARLNQKYFVGQEALYKYEALHLHYPIERGLVTGWDDMEKLWKHLFERELGVKPSQQPVLMTEPSLNPREIREKLAEMMFETFSVPGFYLSNHAVAALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVTKLCMAGRDITEHLTRLLFASGFNFPCILNKAVVNNIKEKLCYIALEPEKELRKSRGEVLGAYRLPDGHVIHFGDELYQVPEVLFAPDQLGIHSPGLSKMVSSSIMKCDTDIQNKLYADIVLSGGTTLLPGLEERLMKEVEQLASKGTPIKITASPDRCFSAWIGASIMTSMSSFKQMWVTSADFKEYGTSVVQRRCF
What is the function of this protein?
Negatively regulates the Hedgehog (SHH) signaling.  Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression.
What are the official names of this protein?
Actin-related protein T1, ARP-T1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Nucleus. Note=Both detected in the nucleus and cytoplasm, localizes to the nucleus where it binds chromatin upon stimulation of the Hedgehog pathway.
Protein: THIO1_SYNY3
Sequence: MAVKKQFANFAEMLAGSPKPVLVDFYATWCGPCQMMAPILEQVGSHLRQQIQVVKIDTDKYPAIATQYQIQSLPTLVLFKQGQPVHRMEGVQQAAQLIQQLQVFV
What are the official names of this protein?
Thioredoxin-like protein slr0233.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: PAFA_GORB4
Sequence: MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLQNGARLYLDVGSHPEYATAECDSLIQLINHDRAGELVLEDLLVDAEQRLSDEGIGGDIYLFKNNTDSAGNSYGCHENYLVVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATFCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMSEMTTLLKVGSAALVLEMIEAGVVFRDFALDNPIRAIREASHDPTGRRPVRLAGGRQASALDIQREYHARAVEHMTNRRPDPEMDMVVDLWGRMLDAVERDDFSKVDTEVDWVIKRKLFQRYQDKYSMELSDPKIAQLDLAFHDIKRGRGVFDVLSRKGLVTRATTDEAIATAVNEPPQTTRAKLRGDFISAAQKAGRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVDRLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: RL18_STRP3
Sequence: MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CH602_VIBVU
Sequence: MAAKDVLFANDARQKMLKGVNLLADAVKVTLGPKGRNVVLDKSYGAPSITKDGVSVAKAIELKDKFENMGAQMVKQVASKANDEAGDGTTTATVLAQALINEGLKAVAAGMNPMDLKRGIDKAVDSAVEKLRAMAQPCSDKESITQVGSISANSDRAIGDIIAEAMEKVGRNGVITVEEGQGLSNELSVVEGMQFDRGYLSPYFITNQDSGAVELDNPYILLVDKKVSSIRELLPVLESVAKASRSLLIIAEDIDGEALATLVVNNLRGIVRAAAVKAPGFGDNRKAMLEDIAVLTAGTVISEEIGLELEKATIEQLGSAKKVTITKDTTTIVGGAAQESAIRDRVATIEKQIENTTSSYDKEKLQQRIAKLSGGVAVIKIGAATEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVALTKIASELADLKGDNDDQNVGIRVALRAMEEPLRQIAINAGDEGSVVANAVKAGDAHYGYNAATGEYGNMIEMGILDPAKVTRSALQYAASVAGLMITTEAMITDHVADTSSEI
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPZ_SHIBS
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: IPIPR_MENPI
Sequence: MAEVQRYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQLDVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAGAKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPRIVNVSSSFGSLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSKAALNAYTKIAAKKYPSFRINAICPGYAKTDITFHAGPLSVAEAAQVPVKLALLPDGGPSGCFFPRDKALALY
What is the function of this protein?
Monoterpene synthase that catalyzes the specific reduction of the 1(2)-double bond of (-)-isopiperitenone to produce (+)-cis-isopulegone.  Does not catalyze the reverse reaction.  Unable to reduce (+)-pulegone, (+)-cis-isopulegone, (-)-menthone or the 1,2-double bond of (-)-carvone.  Able to utilize NADH with 20% the efficiency of NADPH.
What are the official names of this protein?
(-)-isopiperitenone reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLN8_RAT
Sequence: MTPVSNHGVAESIFDLDYASWKIRSTLAVAGFVFYLGVFVVCHQLSSSLNATYRSLLAKEKVFWNLAATRAVFGIQSTAAGLWALLGDPVLYSNKALGQQNWCWFHITTATGFFFFENAAVHLSNLFFRTFDLFLVVHHLFAFLGFLGSAVNLRAGHYLAMTTLLLEMSTPFTCVSWMLLKAGWSHSLFWKVNQWLMIHMFHCRMILTYHMWWVCFQHWDALASSLYLPHLALFLFGLALLTVIINPYWTHKKTQQLLNPVDWNFAQPEAKGDRQERTNGQVPRKKRL
What is the function of this protein?
Could play a role in cell proliferation during neuronal differentiation and in protection against cell death.
What are the official names of this protein?
Protein CLN8.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: WCAM_ECOLI
Sequence: MPFKKLSRRTFLTASSALAFLHTPFARALPARQSVNINDYNPHDWIASFKQAFSEGQTVVVPAGLVCDNINTGIFIPPGKTLHILGSLRGNGRGRFVLQDGSQVTGEDGGSMHNITLDVRGSDCTIKGLTMSGFGPVTQIYIGGKNKRVMRNLIIDNLTVSHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILISDHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLSIPQNFRVNDIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHFFMRNINVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRINHHIVNVEKINFRLPELRE
What are the official names of this protein?
Colanic acid biosynthesis protein WcaM.
Protein: RECX_LACP3
Sequence: MSEITKITAQKRRGRYNIFIDGTYAFPVSETTLVDYRLAKGMVLTAETIAQIKSSEVTAMGLEIGLTYISHQSRTSKEVSDRLAKEDLPADVIQKVLTRLTDLGFLDDADYAHRYIEEHLKMGELGPRTLQHKLQQKGLKPDLLANELAAIPTTAWLDAAVRAGQKNLRHHQHRAYKDQLQRLRVALMQKGFDDTTIQTAIATIDPQPDPEAESDLLKLEAAKQWRLKAKYGDRERKQKV
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAIA_SYNY3
Sequence: MQSPLSLCLFAPEHVAHRLRSIFQGDRHYLSTFQALDDFCAFLEDKPERIDCLLVYYEANSLPVLNRLYEQGRLLPIILLEPSPSALAKTTDEHPTIVYHNAEIHLPESQWSELPTVVDRAIAHYLHLGPICTLPNQTETIPAPIVDESSQSFLLLQQRRLADKLKERLGYLGVYYKRKPSHFYRNFSPQEKQEYLEDLSSQYREIILSYFSDEGTVNDLLDQFVNQAFFADLAISQILEIHMELMDEFSQHLKLEGRSEEVLLDYRLVLIDILAHLGEMYRRSIPREDIPFDVYYQTD
What is the function of this protein?
Binds oxidized quinones via the N-terminal PsR domain, allowing it to sense redox changes and possibly mediate clock input.
What are the official names of this protein?
Circadian clock oscillator protein KaiA.
What is the protein family that this protein belongs to?
Belongs to the KaiA family.
Protein: PLSX_ACICJ
Sequence: MPSPPPTPETATASDRTATPAPGMPILAVDAMGGDSAPGMVIAGLDIAAERHPNARFEVFGDAVQIDELVRLSKRLRNRVSIRPTTEIIPNELKPTAALRLRDASLRRAIDAVANGEAAGVISAGNTGAMLALAKIVLKTMSGIDRPAMAAIGPSARGDVVMLDLGANVVCDARNLVEFAVMGELFARTVLGLPHPTIGLLNVGSEEMKGDETLRRAAEALRESPIGPQFRGFIEGHDIAGGTVDVVVTDGFTGNVALKTGEGALRLVGDLLRRVFSANIASRLAYLLARPGLTRLREWLDPRRYNGAVLLGLNGVVVKSHGGADAEGFAHAVDVAMDMIVNRFNDRIRDDLGRHADRERLASDAFRATPPASATSVTTG
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: G6PI_YERPE
Sequence: MKNINPSQTAAWKALQQHFEQMKDVTISSLFAKDDQRFNRFSATFDDQMLVDFSKNRITSETLEKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHIALRNRSNTPIVVDGKDVMPEVNAVLAKMKQFCDRVISGDWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEALKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLSAAGDPAHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSVGFEHFEQLLSGAHAMDKHFAETPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFPAYFQQGNMESNGKYVDRNGHPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPLSDHHAKLLSNFFAQTEALAFGKSLEDVEAEFAAAGKTPEQVAHVAPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIYTFDQWGVELGKQLANRILPELADDQEVTSHDSSTNALINRFKNWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG33_ZYGRC
Sequence: MSVCLGVTKGIAVSSLGIYAGILTTGTICTYMVPVDVITKHLNSVVCRVGEVASALGLLSTGFFSLSYFGAPSHLRHPYLIYSALVAPASALYLWAISRCNHKCHAKSKIAEQGKTNGDNKTQSPPLGDSVVDLGADSKVPSGHPPVKEGAKCPMGNAVVTNEPSSTDYARPAGCQSKFAKHLAVVTGVAIIGFLQSVIGVYGEPA
What is the function of this protein?
Involved in the selective degradation of mitochondria via autophagy during starvation and at post-log phase.
What are the official names of this protein?
Autophagy-related protein 33.
What is the protein family that this protein belongs to?
Belongs to the ATG33 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: DISA_MYCA1
Sequence: MTRPTLRETVARLAPGTGLRDGLERILRGRTGALIVLGNDENVEAICDGGFALDVRYAPTRLRELAKMDGAVVLSTDGSRIVRANVQLVPDPSIATDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVGGERHVVADSATILSRANQAIATLERYKIRLDEVSRQLSRAEIEDFVTLRDVLTVVQRLELVRRIGQVIDNDVVELGTDGRQLRLQLDELLGGNDNARELIVRDYHASPEPLSEAQMTATLDELDALSDTELLDFTALAKVFGYPTTTEAQDSAVSPRGYRALAGIPRLQFAHADLLVRSFGTLQNVLAASASDLQSIDGIGAMWARHVREGLSQLAESTITDSLS
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: Y079_ATV
Sequence: MVEVLRFKDEKEYREWLSWQSGSVKDKASEYERRYPGTVPIVIELDVDTCPYCGGGEGTHIFIPPHLENIISQIVFDSQ
What are the official names of this protein?
Uncharacterized protein ORF79.
Protein: MDH_METTH
Sequence: MKVSIIGSTGRVGRATALCLAEEEAVKTLHLISRKESLEQNLGEVLDMSDALAAKGVSVKLENSADIENVYGSRIVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVDVMTYVALRYSGFHPSRVFGLGNHLDSLRLKNYMARHFNVHVSEVHTRVIGQHGPYMVPLISSTSIGGIPIEHYARRDYFSGYKKFDLKKTIDKVIHAGSNIISRKGATEYGPAFAISNIVTTILNDERRILTVSTLMEGEIDGIRDVCLGVPVKLGKNGIEGVVPVLMDRDEREAFREAANHVRDSTRRVMEFLDEELPL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: KEFG_ECO57
Sequence: MMSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSAQELASHARAYGDWLANPLSPGGR
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CPXA_PSEPU
Sequence: MTTETIQSNANLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLKYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENACPMHVDFSRQKVSHTTFGHGSHLCLGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV
What is the function of this protein?
Involved in a camphor oxidation system.
What are the official names of this protein?
Camphor 5-monooxygenase, Cytochrome P450-cam, Cytochrome P450cam.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUB_BUCBP
Sequence: MCEKIQKILARHGYGSRRYIESLIKSHSVKINDEVVKVGQRISINVIQKVIINNNNYKPKLNINKSLKVLLYNKPEGEICTRKDQRNRRTIFEKLPKLSNARWINIGRLDLNSSGLLLFTTDGELAYRLTHPSFNIERIYKVRVFGQFTENILKQLNVRVKLLDGYANFKSIQFKYGEGKNKWFNVSLCEGRHRIVRRIWEKLGFQVNKLVRISYAHLTLPKTLFPGTWITLNKHDIDVLCKKVNLR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: RUVC_ANADE
Sequence: MIVLGIDPGSRRCGYGVVAREGARLTVVESGVLVPGDLPMAQRLGRILDGLDALIARARPAEASVEAVFSGASPRSALVLGQARGVALAAAARAGLPVFEYAPSEVKLAFTGNGRAGKDQMLRTARMLLGAAPGLSDEADALAIAVCHLARRAFAVPAAGAGRAAAARAAAARLRPSRRDHRGTP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.