PharMolix/UniProtQA huggingface dataset:
Protein: LEF5_NPVAC
Sequence: MSFDDGVVKAQTDPFALKRGGHNVQKWTSYALFKLFKEFRINKNYSKLIDFLTENFPNNVKNKTFNFSSTGHLFHSLHAYVPSVSDLVKERKQIRLQTEYLAKLFNNTINDFKLYTELYEFIERTEGVDCCCPCQLLHKSLLNTKNYVENLNCKLFDIKPPKFKKEPFDNILYKYSLNYKSLLLKKKEKHTSTGCTRKKKIKHRQILNDKVIYLQNSNKNKLFELSGLSLKSCRHDFVTVESQTRAGDEIASFIRYCRLCGMSGC
What is the function of this protein?
Plays a role in the transcription of late viral genes.  May function as an transcriptional initiation factor.
What are the official names of this protein?
Late expression factor 5.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-5 family.
What are the subcellular locations of this protein?
Host nucleus. Note=Co-localizes with IE1 in the nucleus of infected cells.
Protein: VP3_POLMJ
Sequence: FLSALLGMLKNL
What are the official names of this protein?
Venom peptide PPM3.
What are the subcellular locations of this protein?
Secreted.
Protein: TLP_CLOBL
Sequence: MKNKPDDRKDNVDKIQYNITKTIQNCELADEMIAKTDDEKTKKTLIEKNERRREALDGMREEIKDEARDKKNGYM
What are the official names of this protein?
Protein Tlp homolog.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
Protein: SYL_SALCH
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADSSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPT2_BOVIN
Sequence: MSKQQQTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIICYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQLQLQGGDGDSGVHGQHV
What is the function of this protein?
Filament-forming cytoskeletal GTPase.  Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity).  Required for normal organization of the actin cytoskeleton.  Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin.  Required for the progression through mitosis.  Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression.  During anaphase, may be required for chromosome segregation and spindle elongation.  Plays a role in ciliogenesis and collective cell movements.  In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein (By similarity).
What are the official names of this protein?
Septin-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cleavage furrow. Midbody. Cytoplasm, cell cortex. Cell projection, cilium membrane. Cell projection, cilium, flagellum. Note=Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localized to fibrous or granular structures, depending on the growth state of the cell. Localizes at the base of the cilia near the morphological distinction between the cilia and plasma membranes. Found in the sperm annulus (By similarity).
Protein: CDPF1_BOVIN
Sequence: MACETERTPLGVFKCQLCALTAPYSYQGRQPPDSQSVVLLEESYVMRDPFTPDKGRFLVVGSRCSMCGRLVCVGPECSLFYSKRFCLPCVQDNVDAFPQEIQQDLEKRKVPFTRPASQRSS
What are the official names of this protein?
Cysteine-rich DPF motif domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CDPF1 family.
Protein: SYM1_KLULA
Sequence: MNGFVNWYTASVKRSPRLTNGIMTGSLFGIGDVIAQVGFPEKKGQKYDLARTVRAVVYGSLIFSIIGDSWYKFLNQKVIVKPGKHWTNTAARVGCDQLLFAPVGIPMYYGVMSILEGKSLVDAKKKIEDNWWPTLVTNWYVWPAFQLINFSLVPVHHRLFSVNIISIFWNAFLSFKNSISPSDKKVPVNFPPVPE
What is the function of this protein?
May be involved in cellular response to stress.  Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).
What are the official names of this protein?
Protein SYM1.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PANB_SALPA
Sequence: MKPTTISLLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLVGDSLGMTIQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLSDLPFMAYATPEQACENAAIVMRAGANMVKIEGGAWLVDTVKMLTERAVPVCGHLGLTPQSVNIFGGYKIQGRGDAGQVLLDDALALEAAGAQLLVLECVPVELAKRVTEALSIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAEAGDMRAAVQQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRRD1_MOUSE
Sequence: MSEDGSNVEPGGFPRFESLEEPGSEISDLLDEASPYSKSKDSNQIYEANPSKDTEQSAASFTSQLDRNEEKNTGIPFSETNIADIIPLSIEESLQSSGSSETKMAEDYYPVKFPTGRKFRGRIFNGNQKGLDMKSDNFTVNLDAKGLQEFPVDIVKVKYVKYLYLDKNQIKNFQGIDPGDLLGLEILSLQENGLSSIPLEIQLFHNLKILNASYNEISQIPKELLQLENMRQLLLNSNHIDTLPSGLEHLRYLETLSLGKNMLTYIPDSLSSLKNLRILNLEYNQLTIFSKSLCFLPKLNSLNLTGNMIGSLPKEVRELKNLESLLMDHNKLTFLAVEIFQLPKIKELHLADNKLEAISPKIENFKELRLLNLDKNLLQSIPKKISHCVNLESLSLSDNNIEELPKKIRKLKNLRQLHVNRNKMITMTEEISHLSNIHILEFSGNQITHVPIEIKNCRKITRVELNYNNIMYFPVGLCALQSLDYLSFNGNYISEIPVDMSFSKQLLHLELNRNKLTVFSKHLCSLTNLEYLDLAKNQIMTIPSCISAMVSLHVLILSDNKFESFPKELCSLKNLRVLDISENKLQKIPLEISKLKRIQKLNLSNNIFTNFPVELCQLQTLEELNISQTSGKKLTRLPEEVSHMTQLKILNISNNAIKDIPKNIGELRSLVSFYASNNQISSLPSSFLSLEVLQSLDLRGNNMTALPSGIYKLSSLKEINFDDNPLMRPPMEICKGKEMHMITCYLQRADERDEKILEKIFNIVANSITETNFEFLQQKLNMASSANNMPVRPTTPLNERIYQALIKWKAEKDVQFTATALRDKLFRALNMIGAYDIMDKITALNLYTSAIKL
What are the official names of this protein?
Leucine-rich repeat and death domain-containing protein 1.
Protein: SNPH_RAT
Sequence: MAMSLQGSRRASAGSRRRTSPPVSVRDAYGTASLSSSSNSGSCKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGVAKEEGTGESAGGSPARSLTRSSTYTKLSDPAVCGDRQAGDPSNTPAEDRADSGFVAADDTLSRTEALEASSLLSSGVDCGFEEASLHSSFNLGPRFPASNTYEKLLCGMEAAVQASCMQERAIQTDFVQYQPDLNTILEKVGQAQGCSSVLKDRHSELDLHPSGPRDPDSAVVVTVGDEPEAPEPITRGPAIHRPAVNSNPGLPVSVVCPVEEEEEAAAAAAAAAAATTTTTTTEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCSLSQPSAGSSGGSQL
What is the function of this protein?
Inhibits SNARE complex formation by absorbing free syntaxin-1.
What are the official names of this protein?
Syntaphilin.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Synapse, synaptosome.
Protein: IHFB_ACTSZ
Sequence: MTKSELIELLAKKNPSISTKIVENSVKEILEQMSGSLENSDRIEIRGFGSFSLHYRQPRLGRNPKTGESVKLDAKCVPHFKAGKELKERVDFKA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: AROA_SALGL
Sequence: MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGGPLRAPGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGGDIEVDGSVSSQFLTALLMTAPLAPKDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARMSTPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_ANAMM
Sequence: MSIVSSGDILKILKERIEGFDSPVKTSSVGDVVAIKDGIALVYGLSGVKFGETVAFSSGVRGVVAGLERDTCSVVVFGEDREIREGDSVQCTGELMTVPAGLSVLGRVVNPLGSPVDGGNAIVADSRLPVEAKAPGIMARQPVCEPLQTGIKTVDMLIPIGRGQRELVIGDRKTGKTAIALDTIINQKKTNDTADAKNRMYCIYVAIGQKNSSIARVVHKLKETGAMDYTIVVAAGASDPVSIQYLAPYAACAMGEFFRDNGMHCLIVYDDLSKHAVAYRQMSLLLRRPPGREAYPGDVFYIHSRLLERAAKLSDDLGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFHKGFRPAINVGLSVSRVGSAAQVKSVKKVAGSMKLTLAQYRELEDFARFGSDLDPSSQAMLEKGRRFMELLKQGQYSPLSVEEQVAVVLAGADDCVNGIPVSEISKFERGLLERLRAEHGGLMSSLSADIADDIKGKLLEVIRGFAASF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YB11B_YEAST
Sequence: MESQQLSQHSPIFHGSACASVTSKEVQTTQDPLDISASKTEECEKVSTQANSQQPTTPPSSAVPENHHHASPQAAQVPLPQNGPYPQQRMMNTQQANISGWPVYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKSNMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELTFLCHTFQLFAPSQFLPPWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLATLHYNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLPYARHRCIHMTVADLFSDIHSMYEEQQESKRNKSTYRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNNSQSRTARAHNVSTFNNSPGPDNDLIRGSTTEPIQLKNTHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSNDLNIESDHDFQSDIELYPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTDSGGMHRLDVPLLAPMSQSNTHESSYASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYHITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNLNSNKRIIDKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-BL Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TIAM2_MOUSE
Sequence: MGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLHGWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANTPGNDFQGNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLGKLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQRPSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVEGSFLAPSTPDPSLPSSFPPSDTKKPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVDHRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGSEYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMRELEMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERKLELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEHVFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFSSLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSALRDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALVCKMRQLEPTHYGLQLRKVVDKSVEWCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISDVLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCASWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLDQVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDAISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAMEKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVRLGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSLSSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGSPTKDIEIQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLLKAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
What is the function of this protein?
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities.  Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them.  Activates specifically RAC1, but not CDC42 and RHOA.  Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth.  Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons.  Promotes migration of neurons in the cerebral cortex.  When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane.
What are the official names of this protein?
Rho guanine nucleotide exchange factor TIAM2, SIF and TIAM1-like exchange factor, T-lymphoma invasion and metastasis-inducing protein 2, TIAM-2.
What is the protein family that this protein belongs to?
Belongs to the TIAM family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, growth cone. Cell projection, neuron projection. Perikaryon.
Protein: NMCPA_ORYSJ
Sequence: MFTPQGKGWTGWSTPAPANQRSGGGAPAASAPLGKGKGTTLRVAELEQELHEYQYNMGLLLIEKKEWTAKLDEINQALTQKEEILKREQAAHLNAISEYERREESMRKALGVEKQCVTDLEKALREIRGEIAEVKFMSEKKITDAQSLEASLEEKRLEIEGKLHAADAKLAEANRKKSQADRDLEEVEARQRRLEKEKLYFENERKAGEDRIKRQEDSLRDWDKKLKESQNRILDLQRSLNDREERANENDKLFKIKQEELEEAKKALEHTKATLKIKEDDINKRLAELHLQEKEAESKNRKLEEREKKIAEREEKVSAREKVGLQKLLEDHNVKLESKRRDFDLQLENEKKSFDAMLVQKEADLVQREKDVRSSEEKLSKKEQVLNESKKKLEEWQNDLDTKSNALKKWEESLQNDEKQLSEQKLQIENERKQAEMYKLELESLKATVVAEKEKILQEQNNLKLTEEERQEHIMLTAQLKKEIDEYRMRSNSLSEETEDLRKQRQKFEEEWEQLDEKRTHLEEEAKKLNNEKKNLERWHDNEEKRLKDREDELDIKYKEQGENLALKEKSLIDNIDHQRLENEELLKRERADLQRNLQLHRHELEMEMEKKQASKERELEEKENELNRKMDFVENELKRAAELNESKIQKILLEKKQLQKEKEVLVEDRQKLETDKADIRRDIDSLNTLSKSLKERREAYNRDRNNLIDIFEKYKVCKNCGVIIFEGLDALALKDSTDIEYPSLAVEADDRSPNPDTLAQETGALVNSGGRLSLLQKCSRIFKFSPRKKAEQSSEQQAVKNTDFGARLEEASQSDDDYEPTPVYQVAYNSFDAEDLPSESGAFENEESERQDIADDVQMESSLGVADNCVDIHGTQSFDGNTDMVVDTTIVDVDQNGKDSAVLPVVDLEPETSKQGRRQQNRKGRAKGGVKRTRSVLAVVEDAKEILGENLEVKKDDGQGDSVTVGGTRKRRFAGATISEQDEDSEAHSESVSLGGQRRKRRQTAAAVTQAPGEKRYNLRRTTVANAATAAQTNKKKAAKKGSKQTVEATADDTEGTSKAEEPATGSKGASQSADDASQLPEYSQAEAGDTHGPVEVTSAEGVDIVDGIDAAPDAMPMTPSGSELGAEQDDEEDDDSERRNQSIGKKLWSFFTT
What is the function of this protein?
Architectural component of nuclear structure that plays different roles in controlling nuclear size and morphology.
What are the official names of this protein?
Nuclear matrix constituent protein 1a, OsNMCP1a.
What is the protein family that this protein belongs to?
Belongs to the CRWN family.
What are the subcellular locations of this protein?
Nucleus matrix. Nucleus lamina. Note=Forms aggregated foci in the inner nuclear matrix region (PubMed:15659629). Localizes in the nuclear periphery (PubMed:15659629).
Protein: SYGB_OENOB
Sequence: MADYLLEIGLEEIPAHLVTESENQLIERIKNFFSDNLLDYKKIQTFSTPRRLAVLVHDLSNYSQSKDEELRGPSLKVAKDESGNWSRAAEGFARSQGTSPAEFDERDGYVYLNKHIEGVSAEEILKKIGIEVVEKMKFSTYMKWADFKLEYVRPIRWLVSLLDSKIVPFQILDVKADRFTRGHRFLSGGKISISEAGDYEETLNNAYVIVDAKVRKNSIRNQIRKIADTNDWNLHVDPDLLEEVNNIVEYPTAFAGVFDDKYLNLPEIVLTTSMRDNQRFFYVTNKQGKILPHFISVRNGDSNQIENVVKGNEKVLVARLEDAEFFFEEDQKHNIDFFMKKAERLVFHEKIGTMTEHMKRVEKIAALLANQLAFNDQEKKDLKRAANICKFDLTTAMVGEFAELQGTMAGIYAKIFGENQTVCQALSEQYLPTSSEGDLPKSKVGAMLALADKLDTLFSFFAAGIIPSGSNDPYGLRRAALGIVRIIGQQKWNFSVSKLLHSLKTAVDKHEDGFLIDFADTKEISRKVIEFFLDRIRQQSSDIRYDLLDASTGKVNEGIINYIFKRVRILASHVADPDFRDVIEALTRVQNLAEKNKSNVEIDPELFVTNSEKRLYQLTKDKDPIVLLSKGDHTVYQFLASLKEPINNYFDENMIMDKNPIIKNNRVAQINLLNNLISSLGDLRKVVVK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCS_SHIB3
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCNA_SALAR
Sequence: MGEFSILLQQGNGWFFIPSAILLGILHGLEPGHSKTMMAAFIIAIKGTIKQAFMLGLAATLSHTAVVWLIALGGMYLSRAYAAESVEPWLQLISAIIILGTACWMFWRTWRGEQQWLTGSHHDHDHDHDHDHDHDHDHDHDHDHHGHTYPEGAMSKAYQDAHERAHAADIQRRFHGQKVTNEQILLFGLTGGLIPCPAAITLLLICIQLQALTLGATMVLCFSLGLALTLVAVGVGAAISVQQAVKRWNGFTTLARRAPYFSSILIGLVGLYMGIHGYTGIMQ
What is the function of this protein?
Efflux system for nickel and cobalt.
What are the official names of this protein?
Nickel/cobalt efflux system RcnA.
What is the protein family that this protein belongs to?
Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CX7A2_MOUSE
Sequence: MLRNLLALRQIAQRTISTTSRRHFENKVPEKQKLFQEDNGMPVHLKGGASDALLYRATMALTLGGTAYAIYLLAMAAFPKKQN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7A2, mitochondrial, Cytochrome c oxidase subunit VIIa-liver/heart, Cytochrome c oxidase subunit VIIa-L.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RL31_DESOH
Sequence: MKQEIHPEYHQATARCACGNEFTVGSTKESIKVEICSQCHPFFTGKQKLVDTAGRIERFRRKYAKFEQQKSGK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ISK1_HORSE
Sequence: DSLGREAKCNNNAGGCTKIYNPVCGTDGNTYPNECMLCVENQKRQMPVLIQRSGPC
What is the function of this protein?
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 1, Pancreatic secretory trypsin inhibitor.
What are the subcellular locations of this protein?
Secreted.