PharMolix/UniProtQA huggingface dataset:
Protein: HIS1_METM7
Sequence: MILLALPNKGRISKPVNEILEKAGLKISVHGRSLFAQTVDPEIKVMFARAKDIPEFVRDGVADVGVTGYDLMLERDTEEELEMLLDFKFGNARLVIAAPENSTVNSIKDVKDGMKIATEFPGLTKRYLEKKGLNLEIIELSGATEIAPFIGVSDLICDLTSTGTTLQLNRLKEVENVVSSTTRLVANKKSMEDPEKCAKINQVLSGIKSVLYAQSKRLIMMNAPKDKVSEITSIIPGMGGPTVSEILSNDKMLAINAVIDENKVFETVTNLEMLGARDILVVPIERIL
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPT1_HUMAN
Sequence: MAAAQEADGARSAVVAAGGGSSGQVTSNGSIGRDPPAETQPQNPPAQPAPNAWQVIKGVLFRIFIIWAISSWFRRGPAPQDQAGPGGAPRVASRNLFPKDTLMNLHVYISEHEHFTDFNATSALFWEQHDLVYGDWTSGENSDGCYEHFAELDIPQSVQQNGSIYIHVYFTKSGFHPDPRQKALYRRLATVHMSRMINKYKRRRFQKTKNLLTGETEADPEMIKRAEDYGPVEVISHWHPNITINIVDDHTPWVKGSVPPPLDQYVKFDAVSGDYYPIIYFNDYWNLQKDYYPINESLASLPLRVSFCPLSLWRWQLYAAQSTKSPWNFLGDELYEQSDEEQDSVKVALLETNPYLLALTIIVSIVHSVFEFLAFKNDIQFWNSRQSLEGLSVRSVFFGVFQSFVVLLYILDNETNFVVQVSVFIGVLIDLWKITKVMDVRLDREHRVAGIFPRLSFKDKSTYIESSTKVYDDMAFRYLSWILFPLLGCYAVYSLLYLEHKGWYSWVLSMLYGFLLTFGFITMTPQLFINYKLKSVAHLPWRMLTYKALNTFIDDLFAFVIKMPVMYRIGCLRDDVVFFIYLYQRWIYRVDPTRVNEFGMSGEDPTAAAPVAEVPTAAGALTPTPAPTTTTATREEASTSLPTKPTQGASSASEPQEAPPKPAEDKKKD
What is the function of this protein?
Involved in GABAergic but not glutamatergic transmission.  Binds and traps GABAA receptors in the endoplasmic reticulum (ER).  Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors.  Altered GABAergic signaling is one among many causes of cleft palate (By similarity).  Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one (By similarity).  Required for efficient glycosylphosphatidylinositol (GPI) inositol deacylation in the ER, which is a crucial step to switch GPI-anchored proteins (GPI-APs) from protein folding to transport states (PubMed:29255114).  May play a role in T-cell development (By similarity).
What are the official names of this protein?
Putative lipid scramblase CLPTM1, Cleft lip and palate transmembrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the CLPTM1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KCMB4_MOUSE
Sequence: MAKLRVSYEYTEAEDKSIRLGLFLIVSGILSLFIFGFCWLSPALQDLQATAANCTVLSVQQIGEVFECTFTCGTDCRGTSQYPCVQVYVNNSESNSRALLHSDQHQLLTNPKCSYIPPCKRENQKNSESVMNWQQYWKDEIGSQPFTCYFNQHQRPEDVLLQRTHDEIALLHCFLWPVVAFVVGVLIVVLTICAKSLAVKAEAMKKRKFS
What is the function of this protein?
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel.  Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.  Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics.  May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations.  Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations (By similarity).
What are the official names of this protein?
Calcium-activated potassium channel subunit beta-4, BK channel subunit beta-4, BKbeta4, Calcium-activated potassium channel, subfamily M subunit beta-4, Charybdotoxin receptor subunit beta-4, K(VCA)beta-4, Maxi K channel subunit beta-4, Slo-beta-4.
What is the protein family that this protein belongs to?
Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPG_EXIS2
Sequence: MPKMVHRSKTRPVRVGDLVIGGNNEVIIQSMTTTKTHDVEATVAEILRLEEAGCQIVRVACPEERDALALAEIKSRINIPLVVDIHFNYKLALMAIEAGVDKIRINPGNIGRREKVEAVVTAAKAKNIPIRIGVNAGSLEKHILEKYGYPTARGMVESALHHIKILEDLDFHDIIVSLKASDVQLALEAYQLASESFDYPLHVGITESGPLRTGSLKSAAGLGAILSRGIGNTVRVSLSADPVEEVKVAKEVLKSFGLAANAATLISCPTCGRIEIDLMAIAAEIEDYIDKIQVNIKVAVLGCAVNGPGEAREADIGIAGARNEGLLFRHGEIIRKVPEATMVEELKKEIDAIVLEKEAEKEAAKASQA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PHC2_XENLA
Sequence: MTSGNGSSPVPTAATGNRTQNGENKPPQAVVKPQILTHFIEGFVIQEGAQPFPSHRSRAVLEVGHSSLLTGAQEKYQQSLLAEKVPQQDNNTTTTTTDSEMEETLVPGFPESKGDGDPPKLKCELCGRVDFEYKFKRSKRFCSMACAKRYNVGCTKRVGLFHPDRSKLQKPTVAKHARRRSRKTPLQTVGADPKKQQAAPVTPMNPGPIPSPSALKLSNSQEDSSRCSDNSSYEEPLSPMSASSSLSRARQEHNVEPPNLHSRDPIAMSQDFLPSDPTKWNVEDVYDFVRSLPGCQEISEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKLYARISMLKDS
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
What are the official names of this protein?
Polyhomeotic-like protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUC_STRT1
Sequence: MSGKSIFDKLWDRHVITGDEGQPQLMYVDQHYIHEVTSPQAFQGLRDAGRKVRRPDLTFGTFDHNVPTVNIFDIRDAISKAQIDKLAENVIEFGIDNASHGSDKQGIVHMVGPETGRTQPGKFIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQVKPKKMLLEFTGKPQKGIYSKDYILALIAKYGVACGVGYVVEYRGEAIDRLTMEERMTICNMSIEFGSKMGIMNPDQTTYDYMRGRECVPEDFDAAVADWKTLVSDDDAEYDKVIRMDVSELAPMVTWGTNPSMGVDFDTPFPEVRDMNDERAYHYMGLRPGQKAEDINLGYIFIGSCTNARLSDLQLAARIVKGKKISPNLTAIVVPGSRPVKRAAEKIGLDKIFKDAGFEWREPGCSMCLGMNPDKVPDGVHCASTSNRNFEDRQGFGAKTHLCSPAMAAAAAISGHFVDVRRMPEVQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: 4EBP3_MOUSE
Sequence: MSSSTSCPIPGCRDQLPDGYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTLPAVPPSKLELLKEQKQTEVEITDDEQFEMDM
What is the function of this protein?
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation.  In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-binding protein 3, 4E-BP3, eIF4E-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the eIF4E-binding protein family.
Protein: MRAY_CLOB8
Sequence: MGEAINLLINSKILAPLIMGFLFSIVLGPIFIPILHKLKFGQNIRKEGPKSHQKKSGTPTMGGLIFFIATATAILIMGQKPMSREMILLYSFLAFGFIGFLDDILKIIHKDNLGLRAAQKMILLVLFSVALAWYGYTNVGTDILIPFINQNFRLNLGILYIPFIVVYYAAVTNAVNLTDGIDGLATSVTVIVLTFFAIIGFRTQNVEVAVFAIALAGALLGFLKFNAFPAKIFMGDTGSLALGGVIGTIALMLKMELFVIIVGGIYLIETLSVIIQVTSFKLTGKRVFRMSPIHHHFEQVGWSEVKIVTIFSSITAILCIIGFVAL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMO_CHLAA
Sequence: MKYHIVTLGCPKNAVDSEGMDGLLSTQGHQAVASAEEADVIIVNTCSFIAAARAETLGVLKELAGRKRPGQRLIAAGCMAQSHPHEVAGVQGVDATLGTQQWTQINALVGQLERPVIPLTPGQPVATIPLTTTTNGQPTSYADWRTTQIRRTHQTPSAYLKISDGCNLRCAFCTIPSFKGDMRSKPVGAVLAEAQELVAGGVREIVLVAQHLTDYGRDLGLKDGLATLLAELCQVTPPETWIRLMYAYPHGISERLITTMASYPQICHYLDMPLQHAHPATLRRMRRPPDTDRTLRIIAELRAAMPDIAIRSTFIVGYPGETTAEFHALLEFLQTAQLDRVGAFRYSREPGTPAAELPDQVRPQVIERRWHELMRLQQTISYTRNQRWVGRTIKVLIEGNGTADDGSALSIGRSFRDAPEIDGQVFVWGNYPAGTMIPVQVTQATAYDLWGEALS
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_STRP6
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTRLEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVEAERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_BORPD
Sequence: MTDHSPAPAAQDENRLIAERRAKLSKLREAGVAYPNDFVPDAHAADLHRQYGEQDQEALAAAGVQVKVAGRMMLKRVMGKASFATVQDGSGRIQIYLDRGTLGDEAYAAFKQWDIGDIIAIEGSVFKTNKGELSVHAATARLLSKSLRPLPDKFHGVADQELRYRQRYVDLIMTDATRRTFETRSKAVGSIRQVMLDAGFLEVETPMLHPIPGGAAAKPFVTHHNALDMEMFLRIAPELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYADYRWLMDFTEHVLRQAAIAATGSAVLTYQDRELDLSRPFDRLTICEAILKYAPAYTQAQLDDAAFVRAELKKLGADVDGPVLARAGLGALQLALFEETAEAQLWNPTYIIDYPVEVSPLARASDTRPGITERFELFMTGREIANGFSELNDPEDQAERFRAQVEAKDAGDEEAMYFDADYIRALEYGMPPTGGCGIGIDRLVMLLTNSPSIRDVILFPHLRRED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_CAMJE
Sequence: MGGWSSPSHWLIILLIVVLLFGAKKIPELAKGLGKGIKTFKDEMNNDDEVAKNTQKIEENKNTTNNTNADASIDETKKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: EFG_STAS1
Sequence: MARDFSLDRTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAEWDNHRVNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTIHDRLQANAQPIQLPIGAEDEFEAIIDLVEMTCFKYTNDLGTEIEEIEIPEDHKERAEEARAALVEAVAETDDELMEKYLGDEEISIPELKAAIRKATTDVEFYPVLVGTAFKNKGVQLMLNAVIDYLPSPLDVKPIIGHRADNPDEEVIAKADDNAEFAALAFKVMTDPYVGKLTFFRVYSGTLSSGSYVKNSTKNKRERVGRLLQMHANSRQELNTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILESMDFPEPVIHLSVEPKSKADQDKMTTALVKLQEEDPTFHAHTDDETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMVSYRETFKSSAEVQGKFARQSGGRGQYGDVKIEFSPNETGGGFEFENAIVGGVVPREYIPSVEAGLKDSMENGVLAGYPLIDVKARLFDGSYHDVDSSEMAFKVAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNSGNKAE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAS_SALCH
Sequence: MTVLHSVDFFPSGKAPVAIEPRLPQAAFPEHHHDFHEIVIVEHGTGIHVFNGQPYTISGGTVCFVRDHDRHLYEHTDNLCLTNVLWRSPDAFQFLAGLDQLLPQEQDGYYPSHWRVNQSVLQQVRQLVGLMERAGDGMDAPAVANREILFMQLLVLLRRSSLMEGATKNDAKLNQLMAWLEDHFAEEVCWEAVAEQFSLSLRTLHRQLKQHTGLTPQRYLNRLRLIKARHLLRHSDHSVTEIAYRCGFGDSNHFSTLFRREFNWSPRDIRQGRDAIIQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1404_CLOPS
Sequence: MEGNLLVIDKRVLPEVFEKVINAKRLLKEGKVKEITEATKQAGISRSVYYKYKDYIFEFAETLQGRKVIFNMVVTHEKGVLSSVLNILSDVGGNILTIDQGLPIHGLAHVSFTIDISTMKCDIKEMLNEIELVHGVEKVEFVAME
What are the official names of this protein?
UPF0735 ACT domain-containing protein CPR_1404.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: KDSB_YERPS
Sequence: MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIPWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDLDRVRAIMLNQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y77A_MYCSE
Sequence: MLAGLRRRGSMTTPPGPEIPPPHQGGFYSAGHHPQRPWPETPPPKTRGGVKWMLGAVALLAVVGVTVAVTLAVTGKDKRDAIPPGSGVSGSPTASDIASADDSGPVSVITEDPTCAAQGPILETFAAQQSQLWVERDPALGRESWSPELRADYEKVGKAMRTAADQVAQLAKITPHRAMRELYEQFIAYARAYADNIPNYTPPTDNLARVAVTAADAISYICAAVSYGSAAARAPLVENRPAPTNVAPLGNPSEPERFLTAPNPVCGEWSSVLNAFQTDTTEWLKTDPDISSSQWSIEQKQINENVIPIMKRFANQLYLLGKDSGNPTFRDIADLSVQYRLAYVAAIPTYTPADKYLANASIRLATMANVACRAAAD
What is the function of this protein?
May be involved in the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB (Probable).  Involved in DNA conjugation in the recipient strain (PubMed:18554329).
What are the official names of this protein?
Uncharacterized protein D806_0077.1.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GEP3_CLAL4
Sequence: MLKAQIQTGLQLLQRAAVSHMRPSSCTSMLMRMRVHLAPRALQSQRSLSSSEFSPLIADAILPKCSSCGVLLQNEDRSKPGFYLAPGSSRDFRKETDVVYEKHLASLEEADRDLLLNGAQGLQVSGQKETPKSQKQPANKVSCIRCRDSHYRSQFPLDQFAVAAVSDVMHSIPAYANLAYVVSATDFPMSINEDVFRHRSPREMQFVVTKNDLFFQKNSVASKYGLQFYQDYFWRMFNVPVENVHCVSGTVDWNTEKLFDSLRDNTYFIGCVNSGKSTLIQSLVHLAHKRRLALPNAKRDRALQKIDNQVISTQQEPKTRQALIKHNRALASAFKKQNGPGASYMPGFTRGNLPFELSRSVTIYDVPGFSSAQTAQLYDFLAPQAIKALHKGQKVYKAGTYKSHYETLKSGQVLTVGGLFFLQAPKNTMFQVKNLISHPHHIFKDMEKAMDVWRSPEIYPALKNVFVVPGTRNNAPTPLVKHIVPSFYGSIDLVLRYLGYVSLKPTGAKDPESGPLVVYLPKEVDAIIRQPITKYISRTLSGRDANGNVLRKENWVQKSVTEVKRYTGKTPFTSRLIPAVGEDASADEAEVMERCVEKIKGHAVAHAQISEETKYANWL
What is the function of this protein?
May be involved in the mitochondrial lipid metabolism.
What are the official names of this protein?
Genetic interactor of prohibitins 3, mitochondrial, Found in mitochondrial proteome protein 38.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RUVA_RHOPT
Sequence: MIGKLKGIIDSYGEDYVILDVQGVGYQVHCASRTLQALPSPGEAATLSIETYVREDQIKLFGFRTDTEREWFRLLQTVQSVGAKVALAVLSTLPPHDLANAIALRDKAAVARTPGVGPKVAERIVTELKDKVPALSAVDPAVVKLSGAIDDNRAPRAVTDAISALVNLGYGQPQAAAAVATASRTAGEDAETAQLIKLGLKELSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: LNX2_MOUSE
Sequence: MGTTSDEMVPVEQASSTSSLDPLCFECGQQHWARENHLYNYQGEVDDDLVCHICLQPLLQPLDTPCGHTFCHKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSPVCQDVMQRCDLEAHLKNRCPGASHRRVDLERRKTSQTQTQIEGETGSTVIDPPGTLPPETDCSGTVPGERNLTPASLPVWTEEPGLDNPAFEESAAADSVQQPLSLPEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYDISNVSHNHARAVLSQPCSTLQLTVLRERRFGSRANSHADGSAPRDEVFQVLLHKRDSTEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLNSNDRVLAINGHDLKHGTPELAAQIIQASGERVNLTIARPGKPQPSNGSREAGAHSSSNHAQPPSHSRPGSHKDLTRCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVILKALEVQIAEEAAQATEEQPSAFSENEYDASWSPSWVMWLGLPSALHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSLV
What are the official names of this protein?
Ligand of Numb protein X 2, Numb-binding protein 2.
Protein: ARCA1_STAES
Sequence: MVQGPIQVNSEIGKLKTVLLKRPGKELENLVPDHLSGLLFDDIPYLKVAQEEHDKFAQTLRDEGIEVVYLEKLAAESITEPEVRENFINDILTESKKTILGHETEIKEFFSKLSDQELVNKIMAGIRKEEIQLETTHLVEYMDDRYPFYLDPMPNLYFTRDPQASIGRGMTINRMYWRARRRESIFMTYILKHHPRFKDKDVPVWLDRNSPFNIEGGDELVLSKDVLAIGISERTSAQAIEKLARNIFKDANTSFKKIVAIEIPNTRTFMHLDTVLTMIDYDKFTVHAAIFKEENNMNIFTIEQNDGKDDIKITRSSKLRETLAEVLEVEKVDFIPTGNGDVIDGAREQWNDGSNTLCIRPGVVVTYDRNYVSNQLLRDKGIKVIEITGSELVRGRGGPRCMSQPLFREDI
What are the official names of this protein?
Arginine deiminase 1, ADI 1, Arginine dihydrolase 1, AD 1.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TP7_LITCT
Sequence: FLSAIASMLGKFL
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus (MIC=200 uM).  Shows no detectable hemolytic activity towards human erythrocytes.
What are the official names of this protein?
Ranatuerin-7, Temporin.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
Protein: SCX6_CENEX
Sequence: AREGYLVNKSTGCKYECFWLGKNEFCDKECKAKNQGGSYGYCYSFACWCEGLPESTSTYPLPNKSCGRK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin Cex6.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL19_STRPS
Sequence: MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFEGVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ABCA2_DICDI
Sequence: MGEFKSQLRTLLKKNLLLKGKSKCAICCEILFPIIVILVIFAILVLVMAFKANYDPYNASNFVNRFENTVLLYGNADGALNVEQLGVMNILKNEVATAKNLNSTQIDQLFIEINDQTAMEAFFQNKSDFVFSAVWFNNSALSSGTNPFQYNIRVDSDDVMDTEELIKEDDTSDSEVYVKKRFVATQVAMDQAIFSYFGLNKTLNVKGQRYPDPWTELWQKWIQGRDGIFKDAGSVFITAALMIFGFRLITDLVIEKETKIRESMKMMGLNDLAYFISWMITSLVTALPVNLIISIILKGSSVIHHTNWGVVIFTLILYLLTLLLLAFILSMFFDKSKFCGLLSFVIIIAINIGGIFVAKYDFAPGAKLFLCLISPIAIACSIFAMSARDLEEINTYNWDMMVTENQVIGMLVLDIFFYIFLVWYLDNVVTTEFGTKQKWYFLFTKKYWFPKKCNENGDEQDIESTYQNEDVEMTPVGVGQKVTISIRNLRKEYNTGDGLRVAVNDLYLDMYENQIHALLGPNGSGKSTTIGMMTGLTPPTNGNAFVHGYGILNQMSSVRKHLGVCPQTDIIWQQLTVLDHLKIYASLKGVSPSEIQREAEKMAVEVDLGEKIHSQAGSLSGGQKRKLCLGIAFIGRSDVIFLDEVSSGMDPLSRRVVWDFLLKYKKGRTIILTTHYLEEADYLGDRIAIISHGKLRCDGSSLYLKNKFGCGYLLTCSKILSSMNNFNAQQVTEFIHNYIPEATILSNAGTELSYRLPTASLPHFAQFFREFDDRLQSFGLLTYGISVTTLEEVFLSLGREAALEKGGFNIDQNENQDLEQLRKSIAISSTGVKAGQQFKGLLIKRIKTSIKDAKSFFLTLVIPLVFIIGSIIMYKAMDKPQIFYNNATVPLTMNLGIYSGLENNFVPMQSSNELNWENSLNSSPYFNKFRFIPQTENFEDYLIEGKTNGSFAYKSSAGAINFTLPIDVSSTTIDYTAFYNKDYIHSLPVHINLVNDAVLRKHNNIGIQVTNMPFKHVLSNFDLASEGMNISSIVYFIIIMMAGYALMAGSFAGNVAQERTNRVKRLLYISGCKKYVYWLSNLVWDYFFSFILILLTTCILAGIRENYKSQFGLMFLCLILFCVSVVPLSYLLSYRFASFGKATGAITAIHFAIGIIFVIISLNLRIQVLIDQDVDFQKAADAVDIVFCILSPLFAYSRILFLVSEFPGSVRVGTLKVDNYWSMDYGGSPMIILAAHCIVWVSWIMILDYTPELIGKIRNPKNIEAPPPPDDEDSDVTAERTRLLSVGPNDEPLQFRNLHKLFPAVGKAAPKAAVYNSTLSIPKGQTFGLLGLNGAGKTTTIAMLCGDIVPSSGEVTINGHDLITDRGQALRSNGLCPQFDALITLLSAREQLTLYCAIKGVPEDKVKEVVEAFIKMMDLGAIANSNTGGYSGGNKRKTSLSIAMLGNPSIVSLDEPSTGCDAVVRKYIWNVVSELAKDKVIILTSHSMAEVEALCYRMTIMRDGKMKCLGSIQHIKSKFGAGYTFDVKFKKEYLDSGIQTVLKAIPNSIVLDEHDVMASFEIPNPPDNPVKISTLFESLSHLTILDDYNVSQTSLESVFLKLTGASYEDRLNLNNQKHTSD
What are the official names of this protein?
ABC transporter A family member 2, ABC transporter ABCA.2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: XYLA_YERPY
Sequence: MQSYFNELEQVRYEGSQSTNPLAFHHYNPDEMILGKRMADHLRFAACYWHTFCWGGADMFGANAFDRPWQQPGDALALAKRKAEVAFEFFHKLNVPYYCFHDVDVSPEGASLQEYLNNFAVMTDVLAEKQAASGVKLLWGTANCFTHPRYGAGAATNPDPEVFSWAATQVFTAMNATRQLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDPQLGWDTDQFPNSVEENTLVMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKFAAKMIEDGQLDQIVAKRYAGWNSELGQQILQGKMSLEELSRYASQHNLNPQHQSGHQELLENKVNRYLFG
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.