PharMolix/UniProtQA huggingface dataset:
Protein: VWC2_MOUSE
Sequence: MPSSSAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDSPGRVSELGRASRDEGSSARDWKSKGSRALSGREAWSKQKQAWAAQGGSAKAADWQVRPRGDTPQGEPPAAAQEAISLELVPTPELPEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDNSQCCPQCKEKKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM
What is the function of this protein?
BMP antagonist which may play a role in neural development.  Promotes cell adhesion.
What are the official names of this protein?
Brorin, Brain-specific chordin-like protein, CR (chordin-like cysteine-rich) domain-containing adhesive protein, Cradin, von Willebrand factor C domain-containing protein 2.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Synapse.
Protein: AGN9_PAEDI
Sequence: MADFAQLEVYIGDLSTAITSLITQCQRNGHATGSPSENLSRLFGLEAPTEAHRARESALVILTKLQIMLAGPTDLLQQMTIQTQLLACIRWLGEFQVPACIPLDGSALMKDVSELIDVPENQLGRIVRMAATCGFLREPEPGHITHSALSASFVTNPSYLDAAMFLAETAAPAALDMVAATKQRLGSSEPASQNVVFDQGFFSAANKTQLRRLQRQWQAYLRHGMAHLCDITTDFLTCLEPLRMGNASIVEVGARSAERAMALVDQYPTLHFTVQLSPASTLSSASKNGTAASKVRHPRIRVQHRVPGTPQPIQDAMVYIINFPVPEPGVSYNSPVAQISAELRAHLAPLRMNRSATIVLTAPSLPERGNVAAVGVARIRDLSLLQLANEQEVEMSDLLSLLNGVGDGEGRLVLVNEMRSAGNHGAVALEVKYQSYTDR
What is the function of this protein?
Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of agnestins, dihydroxy-xanthone metabolites.
What are the official names of this protein?
Agnestins biosynthesis cluster transcriptional coactivator AgnL9, Agnestins biosynthesis cluster protein L9.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDH_CHRVO
Sequence: MKAPVRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILHLLDLPQAQTALKGVMMELEDCAFPLLAGMVATDDPNVAFKDVKVALLVGARPRSKGMERKDLLEANGAIFTVQGKALNDHAARDVKVLVVGNPANTNAWIAMKSAPDLDPKNFTAMLRLDHNRALSQIAAKTGKPVASIEKLAVWGNHSPTMYADYRFATIDGQSVKAMINDDVWNRDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHIRDWVLGTNGKWVTMGVPSDGSYGIPEGVMYGVPVVCENGEYKRVEGLEIDAFSRERMDLTLAELEEERAAIAHLFG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: COX1_TINMA
Sequence: MTFITRWLFSTNHKDIGTLYLIFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPVMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSTVETGVGTGWTVYPPLASNLAHAGASVDLAIFSLHLAGVSSILGAINFITTAINMKPPALTQYQTPLFVWSVLITAILLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVAYYAGKKEPFGYMGMVWAMLSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGIKVFSWLATLHGGTIKWDP
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LA_MOUSE
Sequence: MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARNANNGNLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRRRGPMKRGRDGRDREEPASKHKKRENGARDK
What is the function of this protein?
Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
What are the official names of this protein?
Lupus La protein homolog, La autoantigen homolog, La ribonucleoprotein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPE1_CUPNH
Sequence: MHATELNTGHGSQRAIRLAPSILSADFARLGEEVCAIEAGGADLVHFDVMDNHYVPNLTIGPLVCEAIRPLVSIPIDVHLMVEPVDALIPLFAKAGANIISFHPEASRHVDRTIGLIRDHGCKAGLVLNPATPLGWLDHTLDQLDLVLLMSVNPGFGGQAFIPGVLDKVRQARARIDRQVDAGGRPVWLEIDGGVKADNIAAIARAGADTFVAGSAVFGAPDADGGYSSILYRLREAATVT
What is the function of this protein?
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
Ribulose-phosphate 3-epimerase 1.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: AROB_PAEAT
Sequence: MSNEATVIKVTGQSVNENYDVVVGRGLLDTLPAKLGERVRRVLVIHPRALRLTGDTVRDELEAAGFTALTAEIPDAEEGKHIQVAAFCWQVLGQNDFTRSDAIVAVGGGAVTDLAGFVAATWLRGVKVIHMPTSLLGMVDASVGGKTGINTAEGKNLVGSFHPPAAVLADLDTLQTLPKNELISGMAEVIKCGFIADPAILDLVEKNTDAVMDPGSDVVRELIERAISVKADVVSQDLKESGLREILNYGHTLGHAIELVERYSWRHGAAVSVGMMFAAELSRSVGRLSDADADRHRTILESLGLPITYRRDRWQGLLDGMRRDKKSRGDLLRFVVLDGVAKPGILEVPDTSLLFAAYQEIAS
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_ATRBE
Sequence: MVREKVTVSTRTLQWKCVESRTDSKRLYYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRVKFEKVPHEYSTITGIQESVHEIIMNLKEIVLRSNLYGTSEASVCVKGPGYVTAQDIILPPYVEIVDNTQHIASLTEPIDFCIGLQIERNRGYLIKTPQNFQDGSYPIDAVFMPVRNANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHMEEDNLYLQDNQHTVPLSPFTFHDKLAKLIKNNKKIALKSIFIDQSELPSRIYNCLKMSNIYTLLDLLNNSQEDLMKIEHFRSEDIKQILGILEKYFVIDLAKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LIFR_HUMAN
Sequence: MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIKIRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPDTWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEMNPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPNPAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEEDLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSNGGGWSFTNFFQNKPND
What is the function of this protein?
Signal-transducing molecule.  May have a common pathway with IL6ST.  The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
What are the official names of this protein?
Leukemia inhibitory factor receptor, LIF receptor, LIF-R.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 2 subfamily.
Protein: RS2_SODGM
Sequence: MATVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEQTVPLFNDALAELNKIASRKGKILFVGTKRAASEAVKEAANSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELDKLENSLGGIKDMGGLPDALFVIDAEHEHIAINEANNLGIPVFAIVDTNSDPDGVDFIIPGNDDAIRAINLYLTAVATTVRKGRSQDLAEQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PPR19_ARATH
Sequence: MRSIIALMRQREYFVQAIRRTTCVASPALNQTNFQASSFLTTLISSKKSPEETCIGSEEEEEEPNKCLSLRIEKLPKGVTVGSALQSWMGDGFPVHGGDVYHAINRLRKLGRNKRALELMEWIIRERPYRLGELEYSYLLEFTVKLHGVSQGEKLFTRVPQEFQNELLYNNLVIACLDQGVIRLALEYMKKMRELGYRTSHLVYNRLIIRNSAPGRRKLIAKDLALMKADKATPHVSTYHILMKLEANEHNIDGVLKAFDGMKKAGVEPNEVSYCILAMAHAVARLYTVAEAYTEEIEKSITGDNWSTLDILMILYGRLGKEKELARTWNVIRGFHHVRSKSYLLATEAFARVGNLDRAEELWLEMKNVKGLKETEQFNSLLSVYCKDGLIEKAIGVFREMTGNGFKPNSITYRHLALGCAKAKLMKEALKNIEMGLNLKTSKSIGSSTPWLETTLSIIECFAEKGDVENSEKLFEEVKNAKYNRYAFVYNALFKAYVKAKVYDPNLFKRMVLGGARPDAESYSLLKLVEQYKP
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g07590, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL34_THEMA
Sequence: MKRTYQPSRRKRKRTHGFLARKRTPGGRRVLKNRRRKGRWRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GLYA_STRP2
Sequence: MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVMAAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQANCAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAILKQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPVPYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFKEVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQNLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKNSENEAVLEEVRSAVKELTDAFPLYED
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_BRUC2
Sequence: MSEQKSSNQMWGGRFASGPDAIMEEINASIGFDRKLYAQDIQGSLAHAAMLAKTGIIAAEDHKQIENGLKTIRKEIEEGKFTFSRKLEDIHMNIEARLAELIGPAAGRLHTARSRNDQVAVDFRLWVKQELEKTAAALKNLIEAFLERAEEHAATVMPGFTHLQTAQPVTFGHHCMAYVEMFGRDLSRVRDAIERMDESPLGAAALAGTGFPIDRHMTAKALGFREPTRNSLDSVSDRDYALEFLSLAAICAGHLSRLAEEIVIWSTPQFNFVRLSDAFSTGSSIMPQKKNPDAAELVRAKTGRINGSLVALLTIMKGLPLAYSKDMQEDKEQVFDAAENLELAIAAMAGMVRDLTVNVAAMKKAAGSGYSTATDLADWLVRTLGLPFREAHHVTGRAVALAESRKVDLAKLSLEELQSINPAITAEVFGYLTVEKSVKSRQSFGGTAPQEVRRQIRYWKKRIAKA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_MYCTO
Sequence: MLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSAISVADVVASLTRDVADFPVPGVEFKDLTPLFADRRGLAAVTEALADRASGADLVAGVDARGFLVAAAVATRLEVGVLAVRKGGKLPRPVLSEEYYREYGAATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAVVVELAGLSGRAALAPLPVHSLSRL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6867_DICDI
Sequence: MKFIYKLLFILSIVLFLFNNIITINGEIEEVEEINDECSGVRCDKVDKLLCLTSHRPVARYIDRKMAKEKNVLLCCPICLIPSTSFCNHSTSSLHDPKLKYLSGNVYTCYDGEKECNLHTNECEILPQYR
What are the official names of this protein?
Uncharacterized protein DDB_G0286225.
What are the subcellular locations of this protein?
Secreted.
Protein: PPN1_YEAST
Sequence: MVVVGKSEVRNVSMSRPKKKSLIAILSTCVLFFLVFIIGAKFQYVSVFSKFLDDRGDNESLQLLNDIEFTRLGLTPREPVIIKDVKTGKERKLHGRFLHITDIHPDPYYVEGSSIDAVCHTGKPSKKKDVAPKFGKAMSGCDSPVILMEETLRWIKENLRDKIDFVIWTGDNIRHDNDRKHPRTEAQIFDMNNIVADKMTELFSAGNEEDPRDFDVSVIPSLGNNDVFPHNMFALGPTLQTREYYRIWKNFVPQQQQRTFDRSASFLTEVIPGKLAVLSINTLYLFKANPLVDNCNSKKEPGYQLLLWFGYVLEELRSRGMKVWLSGHVPPIAKNFDQSCYDKFTLWTHEYRDIIIGGLYGHMNIDHFIPTDGKKARKSLLKAMEQSTRVQQGEDSNEEDEETELNRILDHAMAAKEVFLMGAKPSNKEAYMNTVRDTYYRKVWNKLERVDEKNVENEKKKKEKKDKKKKKPITRKELIERYSIVNIGGSVIPTFNPSFRIWEYNITDIVNDSNFAVSEYKPWDEFFESLNKIMEDSLLEDEMDSSNIEVGINREKMGEKKNKKKKKNDKTMPIEMPDKYELGPAYVPQLFTPTRFVQFYADLEKINQELHNSFVESKDIFRYEIEYTSDEKPYSMDSLTVGSYLDLAGRLYENKPAWEKYVEWSFASSGYKDD
What is the function of this protein?
Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.  Has both exopolyphosphatase and endopolyphosphatase activities at different ratios depending on divalent cations by cleaving phosphate from the chain end and by fragmenting long-chain polymers into shorter ones, respectively.  The limited digestion products are 1 and 3 P(i) residues (PubMed:11102525, PubMed:11447286, PubMed:15170373, PubMed:15342119, PubMed:15792812, PubMed:8900207, Ref. 16, PubMed:31175919).  Also releases phosphate from dATP.  dATP phosphohydrolase activity is about 7-fold lower than the exopolyphosphatase activity (Ref. 16).
What are the official names of this protein?
Endopolyphosphatase, Deoxyadenosine triphosphate phosphohydrolase, dATP phosphohydrolase, Exopolyphosphatase, Phosphate metabolism protein 5.
What is the protein family that this protein belongs to?
Belongs to the endopolyphosphatase PPN1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Cytoplasm. Note=The cytoplasmic form appears in the cytosol during the transition of cells from stationary growth phase to new budding on glucose addition and phosphate excess.
Protein: SYS_EXISA
Sequence: MLDIKRLRQDFEGIKEKLAHRGEDLSALDRFPQLEEKRRDLINEVEVKKAKRNEATKQIAELKRNKEDAEGPILETRRLGDEIKLLDEELREVEAELNLILLSIPNIPHESTPIGETEDDNVTIREIGTKPEFDFEPKQHWDVMEDLQIVDVERAGKVTGSRFVFYKGLGARLERALINFMMDLHSDEHGYAEVLPPYMVNRDSMTGTGQLPKFEEDAFKVADTNYFLVPTAEVPVTNMHREEILPETQLPIAYTAYSANFRSEAGSAGRDTRGLIRQHQFNKVELVRFVKPEESYEQLELLTGHAEEVLKRLGLPYQVLSMCTADLGFTAAKKYDIEVWMPAQGVYREISSCSNFEDFQARRAGIRFRRDANAKPEFVHTLNGSGLAVGRTVAAILENYQQADGSVVIPEVLRPYMGGKEKIEMPN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED25_ARATH
Sequence: MSSEVKQLIVVAEGTAALGPYWQTIVSDYLEKIIRSFCGSELNGERNPVSTVELSLVIFNSHGSYCACLVQRSGWTRDVDIFLHWLSSIQFGGGGFNEVATAEGLAEALMMFSPPSGQAQPSNDLKRHCILITASNPHILPTPVYRPRLQNVERNENGDAQAESRLSDAETVASYFAKCSVSLSVVCPKQLPTIRALYNAGKPNQQSADLSIDTAKNTFYLVLISENFVEACAALSHSATNLPQTQSPVKVDRATVAPSIPVTGQPPAPVSSANGPIQNRQPVSVGPVPTATVKVEPSTVTSMAPVPSFPHIPAVARPATQAIPSIQTSSASPVSQDMVSNAENAPDIKPVVVSGMTPPLRTGPPGGANVNLLNNLSQVRQVMSSAALAGAASSVGQSAVAMHMSNMISTGMATSLPPSQTVFSTGQQGITSMAGSGALMGSAQTGQSPGPNNAFSPQTTSNVASNLGVSQPMQGMNQGSHSGAMMQGGISMNQNMMSGLGQGNVSSGTGGMMPTPGVGQQAQSGIQQLGGSNSSAPNMQLSQPSSGAMQTSQSKYVKVWEGNLSGQRQGQPVLITRLEGYRSASASDSLAANWPPTMQIVRLISQDHMNNKQYVGKADFLVFRAMSQHGFLGQLQDKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQIPNQQQQQQQQLHQQQQQQQQIQQQQQQQQHLQQQQMPQLQQQQQQHQQQQQQQHQLSQLQHHQQQQQQQQQQQQQHQLTQLQHHHQQQQQASPLNQMQQQTSPLNQMQQQTSPLNQMQQQQQPQQMVMGGQAFAQAPGRSQQGGGGGQPNMPGAGFMG
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Positive regulator of shade avoidance and of jasmonate signaling.  Acts in repression of PhyB-mediated light signaling and regulates the expression of FLOWERING LOCUS T (FT) and of CONSTANS (CO).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 25, AtMED25, Phytochrome and flowering time 1 protein, Phytochrome and flowering time regulatory protein 1.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 25 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APTH1_USTMA
Sequence: MSVLKTLVINPRSGVKPTATLFFLHGLGDSSAGWSDVAQMLSQRPSLSHVRFVLPNAPIQPVTLNMGMPMPSWFDILALDDLSGAEDEAGLLKSTDEIKKLIKAENDGTAKDLDGHKIPSERIVVGGFSQGGAISLLTGLTNPTPVAGVAALSTWLPLRAKIATLRTPTSKTLKVFQAHGDADPVVKYEYGQRTVDFLKNELALNDKDVEFHTYPRMPHSACPEEIRDLAAFLEKVIPAQ
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates.  Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins.  Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
What are the official names of this protein?
Acyl-protein thioesterase 1, Palmitoyl-protein hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1859_PSEAB
Sequence: MLMVISPAKTLDYETPPVTHRFTQPQYLDHAQELIQQLRQLTPLQISELMKLSDKLAGLNAARYASWHPEFTPENAKQALLAFKGDVYTGLNAEDFGEDDFAFAQDHLCMLSGLYGVLRPLDLMQPYRLEMGTRLANARGKDLYAFWGERISQWLNEALAAQGDDVLLNLASNEYFGAVKRKALQARVIDTEFKDLKNGQYKIISFYAKKARGMMARYVIRERLRDPAGLKDFNAHGYYFSAEQSGPDQLVFLRDAPQD
What are the official names of this protein?
UPF0246 protein PA14_18590.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: AHL19_ARATH
Sequence: MANPWWTGQVNLSGLETTPPGSSQLKKPDLHISMNMAMDSGHNNHHHHQEVDNNNNDDDRDNLSGDDHEPREGAVEAPTRRPRGRPAGSKNKPKPPIFVTRDSPNALKSHVMEIASGTDVIETLATFARRRQRGICILSGNGTVANVTLRQPSTAAVAAAPGGAAVLALQGRFEILSLTGSFLPGPAPPGSTGLTIYLAGGQGQVVGGSVVGPLMAAGPVMLIAATFSNATYERLPLEEEEAAERGGGGGSGGVVPGQLGGGGSPLSSGAGGGDGNQGLPVYNMPGNLVSNGGSGGGGQMSGQEAYGWAQARSGF
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity).  Negatively regulates plant innate immunity (PTI) to pathogens through the down-regulation of the PAMP-triggered FRK1 expression (PubMed:20738724).  Positively regulates defense against fungal Verticillium infection (PubMed:21864046).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 19.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAF5_MOUSE
Sequence: MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTPNNGPNGGGGGNVAVAAAAGGDGGTPKPGVAVSAAAPAGAAPVPAAPAEAGAPHDRQTLLAVLQFLRQSNLREAEEALRREARLLEEAVAGSGAPGELDGAGAEAASALLSRVTASVPGSAAPEPPGTGASVTSVFSGSASGPAAPGKVASVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRIYRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13.  The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C.  TAF5 is involved in two modules of TFIID, in TFIID-A together with TAF3 and TBP, and in TFIID-B with TAF8.  Involved in contacts between TFIID and TFIIF in the PIC.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID 100 kDa subunit, TAF(II)100, TAFII-100, TAFII100.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TAF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_LACGA
Sequence: MDLKVTLIKSVAHRLPKQRKIVKALGLGKVNSTVVLPDNAATRGALLKIAHLISVEEVNK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.