PharMolix/UniProtQA huggingface dataset:
Protein: WNT1_CAEEL
Sequence: MLKSTQVILIFILLISIVESLSWLALGLAANRFDRDKPGTSCKSLKGLTRRQMRFCKKNIDLMESVRSGSLAAHAECQFQFHKRRWNCTLIDPVTHEVIPDVFLYENTRESAFVHAISSAAVAYKVTRDCARGISERCGCDYSKNDHSGKSQFQYQGCSDNVKFGIGVSKEFVDSAQRRVLMMKDDNGTSLLGPSQLSADGMHMINLHNNQAGRQVLEKSLRRECKCHGMSGSCEMRTCWDSLPNFRHIGMAIKDKFDGAAEVKVVKEDGIEKPRIVMKNSQFKRHTNADLVYMTPSPDFCESDPLRGILGTKGRQCTLAPNAIDDCSLLCCGRGYEKKVQIVEEKCNCKFIYCCEVRCEPCQKRIEKYLCL
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.  Binds receptor tyrosine kinase cam-1 (PubMed:17942487).  Together with Wnt ligand cwn-2, regulates the migration of CAN, ALM, BDU and HSN neurons during embryogenesis, the migration of QL and QR neuroblast descendants during larval development, and polarity of ALM neurons (PubMed:16109397, PubMed:16516839, PubMed:18622031, PubMed:25917219).  Also acts with the Wnt ligand egl-20 to direct HSN neuron migration (PubMed:16516839).  Acts through the Wnt receptor cfz-2 to direct ALM migration (PubMed:16109397).  Also plays a role in axon growth and guidance in HSN and male CP neurons (PubMed:16109397).  In addition, together with Wnt ligand cwn-2, negatively regulates developmental neurite pruning of AIM neurons probably by acting as a ligand for receptor tyrosine kinase cam-1 (PubMed:19561603).  Probably by activating the Wnt/Frizzled pathway, may regulate vulva development (PubMed:17942487).  May act redundantly with other Wnt ligands such as cwn-2 and mom-2 to control seam cell polarity (PubMed:22022276).
What are the official names of this protein?
Protein Wnt-1.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: AROB_PYRIL
Sequence: MRRFFYRHTRGVTEVVVGRGLPYGEYIERPVVLAEEGLRPPIPGAPTLVLRGGEEVKSLEVLTKVYSFLKEVGADRSTTLVAVGGGALLDLATFAAGTYMRGIRLVHIPTTLLAMVDAALGGKGAVDWGPVKNLVGVFYQPAAILCDLSWLETLPERVYRSAFAEVVKYGLALDGDFYSWVRENAKALLARDWGALEYAVYRSLQLKAGVVEVDEFEERGIRQVLNVGHTVGHAVERVLGLLHGEAVAVGIVAELRLSSELGYLRESHVAEAAEVLSSLGLPTSVKATEQQLAEAAALVKFDKKRRGGHIYIPLVVRPGRWILEKIAVEEVEKAVRYVLHQGG
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL2_BPV5
Sequence: MAVRLRRVKRANPYDLYRTCATGDCPQDVKDRFEHNTIADKILKWGSAGVFLGGLGIGSTQARPGLGTYSPLGRGGVTGRIPVRGPGSTRPLGRPFSSGPIDTIGAGVRTSVETSVTVPDVVAVLPESPAVITPDSMPVDPGVGGLDISAEIIEEPSLTFVEPHGPEDVAVLDVNPAEHDRSVYLSSSTTHHNPSFQGQVTVYTDIGETSETENLLISGSNIGSSRGEEIQMQLFSGPKTSTPETDAVTKVRGRANWFSKRYYTQTSVRDPTFIQEPQTYFYGFENPAYEPDPFEDSFDVQLASPSEPVQPELRDITHVSAARTFRGESGRVGISRLGQKSSIQTRSGVTVGGRVHFRYSLSTIEDAIEDAGEIELQVTNGSQGPSGSLQHTAETILSEGHDAYVDVDMDSVGSLYSDIDLIDEHSETPHGILVFHDEAETDVVPVIDVSYVRKPLSTIPGSDLWPTNINIQNGPVDVDLQDSILPGIIITDSGVDGTYFLNTYLHPSLHKRKKRRFS
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: SPX_LISMO
Sequence: MVTLYTSPSCTSCRKARAWLEEHDIPYKERNIFSEPLSLDEIKEILRMTEDGTDEIISTRSKTFQKLNVDLDSLPLQQLFELIQKNPGLLRRPIIIDEKRLQVGYNEDEIRRFLPRRVRTYQLREAQKMVN
What is the function of this protein?
Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes.  Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP).  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
What are the official names of this protein?
Global transcriptional regulator Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANXA2_CHICK
Sequence: MSTVHEILSKLSLEGDHSLPPSAYATVKAYSNFDADRDAAALEAAIKTKGVDEVTIINILTNRSNEQRQDIAFAYQRRTKKELSAALKSALSGHLEAVILGLLKTPSQYDASELKAAMKGLGTDEDTLIEIICSRTNQELNEINRVYREMYKTELEKDIISDTSGDFRKLMVALAKGKRCEDTSVIDYELIDQDARELYDAGVKRKGTDVPKWINIMTERSVPHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKQLYFADRLYDSMKGKGTRDKVLIRIMVSRCEVDMLKIKSEFKRKYGKSLYYFIQQDTKGDYQRALLNLCGGED
What is the function of this protein?
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids.  It binds two calcium ions with high affinity.
What are the official names of this protein?
Annexin A2, Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In the lamina beneath the plasma membrane.
Protein: PAM17_KLULA
Sequence: MLRLGINLQNRLLVGLNGQSLLKRAVTRNAVAIRMNSTNAGKTASHEMTWPEFFKLRKKERVFNTASSVATAIVFVNGSWFYFSTLEIDPTQTIFGFDPLMAITAGMITCAAVGWLLGPIVGTALFKATSGPKLLQFQEKQLSFLAKIQKNRVNPQSQSFSNPVPDYYGEKINSIPQYRQWLRDCHSYKRKASEFL
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Presequence translocated-associated motor subunit PAM17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSBN1_MICAN
Sequence: METATILGILIAAAVVGITVLALDTAFGPPAAELSDPFEDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN 1.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CH60_LEIXX
Sequence: MAKIIAFDEDARRGLERGLNILADTVKVTLGPGGCNVVLEKKWGAPTITNDGVSIAKEIELDDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVKEGLRNVAAGADPISLKRGIEKAVEAVTAELVGNAKEVESKAQIAATASISAGDTTIGDIIAEAIDKVGKEGVVTVEESNTFGTELELTEGMRFDKGFLSQYFVTDQDRQEAVFEDAYILIANQKISSIKDLLPIVDKVIQANKQLLIIAEDVDGEALATLIVNKIRGIFKSVAVKAPGFGDRRKAMLQDIAILTGGQVISEEVGLKLENVTLDLLGKARKVVITKDETTIVEGAGDPDQIAGRVAQIRGEIDNSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALIQAGKLAFEKLSLEGDEATGANIVKVAIEAPMKQIAINAGMEPGVVVARVRELPLGHGLNAATGEYVDMLIAGINDPVKVTRSALQNAASIAGLFLTTEAVVADKPEKAAPVAAEPGAGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_ALKOO
Sequence: MKVILLQDVKGLGKKGEVVNASDGYARNFLFPKKLAAEATQGNVKTLNEQKTSQELKKQQEVEEAKELAKKIENSPIEIIAKAGDGGRLFGSVTSKDLAETLEKQHHIKIDKRKITLPEPIRELGVRHVEIKLHVGVVGKLTVNIKEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: LRC57_XENLA
Sequence: MGNSALKAHIETAQKTGVFQLTDKGLTEFPEDLQRLSGNLRTIDLSSNKIEVVPPMMGKFSLLKSLSLNNNRISRLPDELCKLKKLETLHLNGNQISQLPADFVQLLALKTLNLSGNRLKTLPAQLFKLRNLDVVDLSKNRIQAIPDEVSGLQAIELNLNQNQISQISVNISHCPRLKVLRLEENCLELSMLPPSILSDSQISLLAVEGNLFEIKKLRDLEGYDKYMEKFTATRKKFA
What are the official names of this protein?
Leucine-rich repeat-containing protein 57.
Protein: CRIPT_XENLA
Sequence: MVCDKCEKKLGTVITPDTWKSGARNTTESGGRKLNENKALTSKTARFNPYGKNKFAICRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLETKNYKQTSV
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
Cysteine-rich PDZ-binding protein, Cysteine-rich interactor of PDZ three, Cysteine-rich interactor of PDZ3.
What is the protein family that this protein belongs to?
Belongs to the CRIPT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYR1_SQUAC
Sequence: MATLFLDDGSSFKGRLFGASSTVSGEVVFQTGMVGYPEALTDPSYLSQILVLTYPLIGNYGIPKDEEDEHGLSKWFESAKIHAAALVIGENSQNPSHWSSVRSLDQRLKEHGIPALEGIDTRSLTKKIREKGTLLGKLVIDGTDENSLPYDDPNKRHLVKEVSIKEPKVYHPSGNVKIMAVDCGMKYNQIRSLCKRGAAVTVVPWDYLFDSNEFDGLFISNGPGDPEYCQQTINNVKKAISEEKPKPLFGICLGHQILSLAIGAKTYKMKYGNRGHNQPCIHEGTQRCFYTSQNHGFAVEPCSLPRDWSVLFTNANDQSNEGIIHNSKPLFSVQFHPEHKAGPTDLVDLFDIFLECARDVKLGVNLDKTVKGRVISHYSFKNGTENSKTPPGRIQPHKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENVQSVLINPNIATVQTSKGLADKVYFLPITPEYVTQVIMNERPDGILLTFGGQTALNCGVELQKRGVLEKYHVRVLGTPVSSIEMTEDRKIFVEKMAEINEYVVPSEAAFTLEQAQGAAERLGYPVLVRAAFALGGLGSGFAQNKEELVTLVTQAFAHTSQILVDKSLKGWKEIEYEVVRDAYDNCITVCNMENVDPLGIHTGESIVVAPSQTLNDKEYNLLRTTAIKVIRHLGVVGECNIQYALSPESEQYFIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPVLRNSVTNSTTANYEPSLDYCVVKVPRWDLSKFLRLSTKIGSSMKSVGEVMAIGRNFEEAFQKALRMVDENCVGFDHTLKPASDEELETPTDKRIFVLAAALRAGYEIDRLYELTKIDKWFLHKMKNIVEYSLKLSELYMKDEVPRHDLLKVKRLGFSDKQIAMAIQSTELAVRRLRQEWKILPVVKQIDTVAAEWPAQTNYLYLTYNGEGHDLDFTKPHVMVIGSGVYRIGSSVEFDWCAVRCIQQLRKMGYKTRMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGIILSMGGQLPNNIAMDLHRQQCRILGTSPESIDTAENRFKFSRMLDTIGISQPRWKELSDTESSKQFCTKVGYPCLIRPSYVLSGVAMNVAYSDNDLEKFLSSAVAVSKEHPVVISKFIQEAKEIDVDAVACDGVVIAVAISEHVENAGVHSGDATLVTPPQDLNQKTTERIKAIVHAIGQELQATGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDMIALATKVIMGEEVEPVGLMTGTGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNILLSIGSYKNKSELLSTVQSLEQLGYNLYASLGTADFYTEHGVKIKAVDWPFEDTDNGCPLKERHRNIMDYLEENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRLAVDYSVPLIIDIKCTKLFVEALRLVGDTPPVKTHIDSMSSHKLIRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMVCAMPNTNPAITDQTSFALVQKLATAGARCDFALFLGASSDNADVLPLISNSAAGLKMYLNDTFSTLKMDNVSLWMEHFEKWPKHLPIVVHAERQTVAAILMVAQLYQRPVHICHVARKEEIQIIRAAKQKGVQVTCEVAPHHLFLNEEDLESIGHGKGQVRPMLSTKEDVNALWENLDVIDCFATDHAPHSVEEKNSDSPPPGYPGLETMLPLLLTAVSEGRLTIDDLVKRLYENPRKIFSLPVQENTYVEVDLEQEWIIPSYMQFTKSKWTPFEGKKVKGRVRRVVLRGEVAYIDGQVLVPPGYGQDVRAWPLGVPLPPPPTTVKTPEHSKPTQTETVRTRTASPRRLASSGPAVDARFHLPPRIHRCSDPGLPNAEGEYKEKPVKKFIEQDTVSQDGYIYPPPVSRLLSPQNLAAQAVPHPYSLLLHPFVGQHILSVKRFTKDQLSHLFNVAHNLRLTVQKDRSLDILKGKVMASMFYEVSTRTSSSFRAAMHRLGGSVIHFSEATSSVQKGESLLDSVQTMSCYVDVVVLRHPEPGAVELAAKHSRKPIINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLAYLLTLYRVNLRYVTPRNLRMPPNIIRFLASRGIKQEEFDSLEEALPDTDVLYMTRIQKERFASEEEYEACFGQFILTPHIMTKGKKKMVVMHPLPRVNEVSVEVDSDPRAAYFRQAENGMYVRMALLATVLGKF
What is the function of this protein?
This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
What are the official names of this protein?
CAD protein.
What is the protein family that this protein belongs to?
In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SOX10_MOUSE
Sequence: MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQDGEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGEAEQGGAAAIQAHYKSAHLDHRHPEEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSLGEGGKPHIDFGNVDIGEISHEVMSNMETFDVTELDQYLPPNGHPGHVGSYSAAGYGLGSALAVASGHSAWISKPPGVALPTVSPPGVDAKAQVKTETTGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHAGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
What is the function of this protein?
Transcription factor that plays a central role in developing and mature glia (PubMed:24204311, PubMed:27532821).  Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (PubMed:24204311, PubMed:27532821).  Once induced, MYRF cooperates with SOX10 to implement the myelination program (PubMed:24204311).  Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).  Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
What are the official names of this protein?
Transcription factor SOX-10, Protein SOX-21, Transcription factor SOX-M.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL32_METEP
Sequence: MAVPKRKTSPSRRGMRRSADALKAPTYVEDKDSGELRRPHHIDLKTGMYRGRQVLKVKSAEA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NDK_SULDN
Sequence: MERTLSIIKPDAVAKGVVGKILDRFESNGLKIAATRKMQLSRADAEAFYAVHSERPFFGDLVDFMISGPVVVSVLEGEGALIKNRNLMGATNPKEAEAGTIRADFAENIDANAVHGSDSLENAAVEIAFFFSEREIS
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_PSEA6
Sequence: MYAILQKFLFTQDAEWSHDFTINWLKRTQHNFLNVAYKQHIDDKPVEFLGITFKNPVGLAAGLDKNAECIDAFAAMGFGFIEVGTVTPKAQAGNDKPRMFRLPAGQAIINRMGFNNKGVDYLVEQVKQAKYKGVLGINIGKNKTTPEDEALNDYLICLRKVYAHASYVTVNISSPNTPGLRNLQYGDALTQLLEGLKEEQANLEVKHNKRVPILIKIAPDLEDSELDSMVDSFLTVGIDGVIATNTTLDRDRVKGQEHAEEAGGLSGSVLTDKSQQIVSSLCTKLAGNVPVIGVGGIDSPHAAKARIEAGSPLIQVYSALIYQGPKLIKEIVDSL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRB_GLUOX
Sequence: MPERPSVPRHLLGIEGLSAEQLVPFLDLAESYALLSRSRSAPRDALRGRTVINLFYEDSTRTRTSFELAGKRLGADVINMSVATSSVNKGETLLDTAATLNAMRCDLLVVRHAQSGAPALLSRKVEASVVNAGDGTHEHPTQALLDALTIRRHFGRLEGLTVAICGDVGHSRVARSNIHLLTAFGNRVRLAGPPTLLPGAMAGLGNVELYSDMDRALEGADVVMSLRLQKERMGAGLVPSAREYFHFFGLDRRRLALAKPGALVMHPGPMNRGVEIASDVADSDQSVISEQVEMGVAVRMAVLDRLSRARMPA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: BPE_ARATH
Sequence: MDPSGMMNEGGPFNLAEIWQFPLNGVSTAGDSSRRSFVGPNQFGDADLTTAANGDPARMSHALSQAVIEGISGAWKRREDESKSAKIVSTIGASEGENKRQKIDEVCDGKAEAESLGTETEQKKQQMEPTKDYIHVRARRGQATDSHSLAERARREKISERMKILQDLVPGCNKVIGKALVLDEIINYIQSLQRQVEFLSMKLEAVNSRMNPGIEVFPPKEVMILMIINSIFSIFFTKQYMFLSRYSRGRSLDVYAVRSFKHCNKRSDLCFCSCSPKTELKTTIFSQNMTCFCRYSRVGVAISSSKHCNEPVTLCFYSYCLRKIYHFLLWNLKYKIQKSVLFS
What is the function of this protein?
Involved in the control of petal size, by interfering with postmitotic cell expansion to limit final petal cell size.
What are the official names of this protein?
Transcription factor BPE, Basic helix-loop-helix protein 31, AtbHLH31, bHLH 31, Protein BIG PETAL, Transcription factor EN 88, bHLH transcription factor bHLH031.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2687_STAAT
Sequence: MKKQDISVKTVVAIGIGAAVFVILGRFVVIPTGFPNTNIETSYAFLALISAIFGPFAGLMTGLVGHAIKDFTTYGSAWWSWVICSGIIGCLYGWIGLKLNLSSGRFSRKSMVYFNIGQIIANIICWALIAPTLDILIYNEPANKVYTQGVISAVLNIISVGIIGTILLKAYASSQIKKGSLRKE
What are the official names of this protein?
UPF0397 protein USA300HOU_2687.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS5_HAEI8
Sequence: MTNITIIDTGCANLSSVKFAFDRLGYNTEITFDLNKIKSADKLILPGVGTANAAMYNLQERQLIETIQNLTQPVLGICLGMQLMTEFSEEGNVPTLNLISGKTNRIPDTGLPLPQMGWNRVQFVKNCPLFDGIVQNSHFYFVHSYAVSPNEHSVAISNYGVNFSAAIAKENFYGVQFHPERSGKNGALLLKNFVEKVPF
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFD_HELPJ
Sequence: MIQSSLYRALNKGFDYQILACKDFKESELAKEVISYFKPNIKAVLFPELRAKKNDDLRSFFEEFLQLLGGLREFYQALENKQETIIIAPISALLHPLPKKELLESFKITLLEKYNLKDLKDKLFYYGYEILDLVEVEGEASFRGDIVDIYIPNSKAYRLSFFDAECESIKELDPATQMSLKEDLLEIEIPPTLFSLDEPSYKDLKTKVEQSPLNSFSKDLTSFGLWFLGEKANDLLGVYQSIISPRALEEIQELASLNELDDERFKFLKVLENAQGYEDLEIHVHALEGFIALHSNRKITLLAPNKTILDNSISVLDAGNMECVIAPFVLNFKTPDRIFISLNSFERKKKRQKSKLALNELNAGEWVVHDDYGVGVFSQLIQHSVLGSKRDFLEIAYLGEDKLLLPVENLHLIARYVVQSDSVPVKDRLGKGSFLKLKAKVRAKLLEIAGKIIELAAERNLILGKKMDTHLAELEIFKSHAGFEYTSDQEKAIAEISRDLSSHRVMDRLLSGDVGFGKTEVAMHAIFCAFLNGFQSALVVPTTLLAHQHFETLKARFENFGVKVARLDRYIKTSEKSKLLKAVELGLVDVLIGTHAILGTKFKNLGLMVVDEEHKFGVKQKEALKELSKSVHFLSMSATPIPRTLNMALSQIKGISSLKTPPTDRKPSRTFLKEKNDELLKEIIYRELRRNGQIFYIHNHIASISKVKTKLEDLIPKLKIAILHSQINANESEEIMLEFAKGNYQVLLCTSIVESGIHLPNANTIIIDNAQNFGLADLHQLRGRVGRGKKEGFCYFLIEDQKSLNEQALKRLLALEKNSYLGSGESIAYHDLEIRGGGNLLGQDQSGHIKNIGYALYTRMLEDAIYELSGGKKRLEKSVEIQLGVSAFLNPELIASDSLRLDLYRRLSLCENVDEVGQIHEEIEDRFGKMDDLSAQFLQIITLKILANQLGILKLSNFNQNITLTYSDEKKESLKAPSKDDNDILETLLKHLHAQISLKRR
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_SOLUE
Sequence: MLTIALDAMGGDHAPKAEVEGAVRAAGSLGVKVILVGQQDVVRRELEQHEGHRDLPIEIVHASERVTMEDSAAKAVRSKRDSSMRVASRLVRDGCAQGFVSAGNTGAVMATAKMVQGVVPGVDRPALLGVFPTMQGNPVVLVDVGANVDCSPEMLAQFAVMGDIYSRNILHRRNPRVGLLSIGEEEHKGNDLTRAAWPLLKSLRINFIGNVEGRDMYAGNVDVIVCDGFIGNVALKVSEGLVDMFKKLLRESLEATISGKIGYALSKSALTNFRKRLDHSEYGGAPLLGVRGGCIIGHGSSNANSIKNAIRVAAEFSGGKVNQQIEEELLRLGKAGD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: VLOM_LAMBD
Sequence: MRNVCIAVAVFAALAVTVTPARAEGGHGTFTVGYFQVKPGTLPSLSGGDTGVSHLKGINVKYRYELTDSVGVMASLGFAASKKSSTVMTGEDTFHYESLRGRYVSVMAGPVLQISKQVSAYAMAGVAHSRWSGSTMDYRKTEITPGYMKETTTARDESAMRHTSVAWSAGIQINPAASVVVDIAYEGSGSGDWRTDGFIVGVGYKF
What is the function of this protein?
Incorporated into the outer membrane of the host during infection.  Lom is expressed during lysogeny in E. coli.
What are the official names of this protein?
Outer membrane protein lom, ORF 206A.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. Ail family.
What are the subcellular locations of this protein?
Host cell outer membrane; Multi-pass membrane protein.
Protein: YOAA_ECOLI
Sequence: MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVEAGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKGRSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPLVTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPEADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLAQSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDAAFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSWIFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVLRNLPQTNQPGSARQLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIARAVRFLAIPSSR
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase (By similarity).  Involved in the repair of replication forks and tolerance of the chain-terminating nucleoside analog 3' azidothymidine (AZT).  May unwind potentially damaged 3' nascent ends such as those terminated by AZT, promote repair and AZT excision (PubMed:26544712).
What are the official names of this protein?
Probable ATP-dependent DNA helicase YoaA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily.
Protein: ASNA_FUSNN
Sequence: MAYISSLDILETEIAIKKVKDFFESHLSKELDLLRVSAPLFVIPESGLNDNLNGTERPVSFDTKSGERVEIVHSLAKWKRMALYRYNIENDKGIYTDMNAIRRDEDTDFIHSYYVDQWDWEKIISKEDRNEEYLKDVVRKIYSVFKKTEEYITTEYPKLTKKLPEEITFITAQELENKYPNLTPKNREHAAAKEYGAIFLMKIGGKLSSGEKHDGRAPDYDDWDLNGDIIFNYPLLGIGLELSSMGIRVDEKSLDEQLKIANCEDRRSLPYHQMILNKVLPYTIGGGIGQSRICMFFLDKLHIGEVQASIWSQEVHEICRQMNIKLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.