PharMolix/UniProtQA huggingface dataset:
Protein: NU1M_DROAZ
Sequence: MEFILSLVGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALIGFKILLFSFL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1776_VIBC3
Sequence: MSTPFWQSKTLDQMTEAEWESLCDGCGKCCLHKLMDEDTDEIYYTNVACSWLNSDTCSCKDYPNRFSSGEECLKLTRDKIEEFNWLPDTCAYRLLGNGQTLPEWHPLLTGSKDAMHAADESVRGKIVYEVDVIDWEDHIVLMSRD
What are the official names of this protein?
UPF0260 protein VC0395_A0576/VC395_1072.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: HEK2_ASHGO
Sequence: MTMTDSSSPAPEGPAAPAEAAAPAKVDAQAPLVTLRLLLSLKEAARILGRGGNTIDNIRKANGVKIGISTKEKSCSDRLLEVTGSIDAVANSLADVVKVLTADDTNEEDAEPEPEQHIFKHLNFILPPPSPDEAEDPMKVKQIGNLRLIVTNSQVSSIIGTAGSKIKKLIDTHSSKLVVSKTFLPDSQDRILEIQGFPNSIANCIKDISQTLIKDDVLDTKEKRYYPHSKHSKDIHVTATVAIPAEYVGALLGHGGNRIANLRKYTRTKITVAQEPNQNNEREFTITGNDQKSVKLAQNMIMKNLGTEKERRLEKQ
What is the function of this protein?
RNA-binding protein involved in the correct localization of transcripts in the cell.  RNA localization is a widespread mechanism for achieving localized protein synthesis.  Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).
What are the official names of this protein?
Heterogeneous nuclear rnp K-like protein 2, KH domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the HEK2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Nucleus. Chromosome, telomere.
Protein: SECB_ERYLH
Sequence: MADEGDVLTDLDMDPAAGGNGADNRPTAGFITQYIKDMSVENPNAPGVYQWQEQPQIDLQFNIGANAVNEEVTEVELKINVEAKTDQGALYIIELVYAGLVGIRNLGDDQAHMFVYAEAPRILFPFARRVIADATRDLGFQPLMLDPIDFNGLYMQRLQQKAAEEAQGEGGETPAGDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_FRATM
Sequence: MRHRKQGRKFGRTSSHRKAMFKNMSASLINHELIKTTLPKAKELRTIVEPLVTLAKREHKLRQELDTNSNEFKAQSVALRRQAFDFLRNKAAVTKLFEEFGARYAERAGGYTRILKCGYRFGDKAPMAFIELVDRPQVEEAADEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CEP43_MOUSE
Sequence: MAATTAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNENLKKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFHPETSTIQGLEGRENLAQDLGIIEAEGTVGGPLLLEVIRRCQQKEKGPASVEGALDLSDGHPPSKSPEGKSSANSTPSKIPRYKGQGKKKTIGQKPGDKKTSSETSQSEPSVSLSESKSKSSLHSLAHETRIASFLSSSAVDARDSSALCPDGDDVEGDSFFDDPIPKPEKTYGWRAEPRKQVGGLASLSDKPHLRSGLSSLAGAPSLTDPESKRGSTVLKDLKLVGEKIGSLGLGTGEDEDYADDFNSASHRSEKSELSIGEEIEEDLSMGVEDGNTSDKLDDLTQDLTVSQLSDVADYLEDVA
What is the function of this protein?
Required for anchoring microtubules to the centrosomes.  Required for ciliation.
What are the official names of this protein?
Centrosomal protein 43, FGFR1 oncogene partner.
What is the protein family that this protein belongs to?
Belongs to the CEP43 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Associated with gamma- tubulin. Localizes on both mother and daughter centrioles. Localizes to an axial position on the mother centriole. Localizes to the distal end of the centriole partly to the subdistal appendage region.
Protein: HIS9_CLOAB
Sequence: MVFDTHLHTLFSTDSKMNIEEAIDAGEKKNLGIIITEHIDLNYPVKGEFVFDIDKYFKEYNKYRSNKVLLGVEIGMGEEIKEQNKSINDKYEFDYVLGSIHLLNGLDLYEKTIYKSSPKKEVFEMYFKTMLACLRCHEYIDSLAHIDYISRYAAYHDGEIYYNEYSDYIDEVLKFIVDREIVIEINTRRLNKKEVCENLMPIYKRYSELGGRFVTIGSDSHYKDSIGLNFKNALKMAENCNLKPVFFEKRLMKYA
What are the official names of this protein?
Probable histidinol-phosphatase, HolPase.
What is the protein family that this protein belongs to?
Belongs to the PHP hydrolase family. HisK subfamily.
Protein: CYSI_SERP5
Sequence: MSDKHPGPLVVEGKLADAERLKKESNFLRGTIAEDLKDGLTGGFTGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMMLRCRLPGGIISPQQWLGIDKFAQESTLYGSIRITNRQTFQFHGILKGNVKPVHQLLGRLGLDALATANDVNRNVLCTSNPVESELHQEAYEWAKKISEHLLPRTRAYAEVWLDQEKVATTDEEPILGATYLPRKFKTTVVIPPQNDVDLHANDMNFVAIAKNGKLVGFNLLVGGGLSIEHGNKKTYARQASEFGYIPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVDTFRAEVEKRAGITFEPIRPYEFTGRGDRIGWVKGIDNQWHLTLFIENGRLLDYPGRPLKTGVAEIARIHKGDFRLTANQNLIVAGVPESEKAKIEALARDHGLIDDGVSVQRQNSMACVSFPTCPLAMAEAERFLPEFVTKVEGILHRHGVGDEHIVLRITGCPNGCGRALLAEIGLVGKAVGRYNLHLGGNREGTRIPRMYRENINEEEILREIDQLVGRWATERTAGEGFGDFTIRAGVVRPVVDPAQDFWD
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: LACC_STRPF
Sequence: MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGDKGLNVCRVLNDFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEILEKGPLLSVEEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIGIANLNGKKTVLDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWIIVSLGADGVFAKHNDTFYNVDIPKIEIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: VATA_DEIDV
Sequence: MTQNKQGVVQSIAGPAVIADGMYGAKMYDIVRVGRERLVGEIIRLDGNTAFVQVYEDTSGLTVGEPVETTNLPLSVELGPGMLNGIYDGIQRPLDKIREASGDFIARGIEVSSLDRTKKWAFTPSVQPGDTVVGSGILGTVPEFSFTHKILTPPDKGGKLRWVAAAGEYTIDDTIAELEDGTKLRLAHYWPVRAPRPVQKKLDPSLPFLTGMRILDVLFPLVMGGAAAIPGPFGSGKTVTQQSVAKYGNADIVVYVGCGERGNEMTDVLVEFPELVDPKTGGPLMHRTILIANTSNMPVAAREASVYTGITLAEYFRDQGYSVSLMADSTSRWAEALREISSRLEEMPAEEGYPPYLGAKLAAFYERAGAVKTLSGDDGAVSVIGAVSPAGGDMSEPVTQATLRITGAFWRLDAGLARRRHFPAINWNGSYSLFTPILDKWYRQNVGPDFPELRQRITNLLQQEAALQEVVQLVGPDALQDNERLIIETGRMLRQDFLQQNGFDPVDASASMPKNYGLMKMFLKFYDEADLALKNGSTIDEIIQNPVIEKLARARYTPENEFAAYGEGVMDQLSTTFKGVKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: KAX33_LEIHE
Sequence: GVPINVPCTGSPQCIKPCKDAGMRFGKCMNRKCHCTPK
What is the function of this protein?
Potent inhibitor of shaker potassium channels as well as the mammalian homologs of shaker.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 3.3, Agitoxin-3, AgTx-3, AgTx3.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACT2_SUIBO
Sequence: MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAFYVSIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGFSLPHAILRLDLAGRDLTDCLIKNLTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSALEKSYELPDGQVITIGNERFRAPEALFQPAFLGLESAGIHETTYNSIYKCDLDIRRDLYGNVVLSGGTTMFPGIADRMQKELTSLSPSSMKVKIVAPPERKYSVWIGGSILASLSTFQNLWCSKQEYDESGPGIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ENGB_LARHH
Sequence: MPLFQNATFFTTVNHLRDLPPTSAEIAFVGRSNAGKSSAINALANRTRLAYVSKTPGRTQHINFFRLASHFDYFLVDLPGYGYAEVPESVRAHWVELLGRYLQTRESLIGLLLIMDARHPLKELDMRMLDFFRMRGQPVHILLSKSDKMNRQEQNKTLATVRQALAGYPQVSIQLFSSSKKQGLEQVETVVAGWFAGLEARQADELTDGEPDDRTPDPDSAS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: TINAL_MOUSE
Sequence: MWGCWLGLLLLLLAGQAALEARRSRWRRELAPGLHLRGIRDAGGRYCQEQDMCCRGRADECALPYLGATCYCDLFCNRTVSDCCPDFWDFCLGIPPPFPPVQGCMHGGRIYPVFGTYWDNCNRCTCHEGGHWECDQEPCLVDPDMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSTVMNMNEIYTVLGQGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHHQQGCRGGRLDGAWWFLRRRGVVSDNCYPFSGREQNEASPTPRCMMHSRAMGRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLGVWGRVGMEDMGHH
What is the function of this protein?
May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells.  This is a non catalytic peptidase C1 family protein.
What are the official names of this protein?
Tubulointerstitial nephritis antigen-like, Adrenocortical zonation factor 1, AZ-1, Androgen-regulated gene 1 protein, Tubulointerstitial nephritis antigen-related protein, TARP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NANR_ECOLI
Sequence: MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids (PubMed:9864311, PubMed:12897000, PubMed:23935044).  Represses expression of the nanATEK-yhcH, nanCMS and yjhBC operons.  Acts by binding directly to the Nan box, a region of approximately 30 bp covering the promoter region (PubMed:23935044).
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.
Protein: Y1238_STAAR
Sequence: MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGIQKGDKIVQIGKYKISEFDDVDKALDKVKDNKTTVKFERDGKTKSVELTPKKTERKLTKVSSETKYVLGFQPASEHTLFKPIVYGFKSFLIGSTYIFSAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTWNDIRRYFL
What are the official names of this protein?
Putative zinc metalloprotease SAR1238.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URED_ALIF1
Sequence: MPKINTSSSGWLADISLFYEKRGTNTKLVHREQVGPLMVQRPFYPETGIAHTYLLHPPGGVVGGDQLNINIHVSPQAHSLLTTPGATKFYRSSGATSSQTQNLTVESDGFLEWLPQENIFFPDSQAQLKTQVELHKNAHFIGWEMNCFGRPVLDEIFENGFVTGRTNIKVDDQLLLSESMYIDSIDEIKHAAGMRHYPMLGNLYIYPASEALEEKLRTLIDENFHEQPELFGSSNPICGITEIDGLLVIRYLGHQTEPMMACFSTLWQHTRQHWLGKLPEVPRIWAT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_RHIE6
Sequence: MNAIVEQLKSTAAATKATDLRAAFAADAQRFSRFSVALDDLLMDFSKTAVNDDILKLLVKLAEDGGVEKKREEMFSGKAINFTEDRAVLHTALRNRSNTPVLVDGKDVMPDVNAVLAAMGKFADEIRSGALKGATGKAITDVINIGIGGSDLGPVMATLALAPFHDGPRAHFVSNIDGAHIADILKLVQPETTLFIVASKTFTTVETMTNAQTARNFIAKALGEAAVQHHFAAVSTALDKVAAFGIDSARVFGFWDWVGGRYSIWSAIGLPLMIAIGPENFGKFLDGAHAVDNHFRKAPITENLPMLLGLIGFYHRNVLGYPTRAILPYDQRLSRFPAYLQQLDMESNGKGVTIDGTPVEGNSGPVVWGEPGTNGQHAFYQLIHQGTSIIPAEFMIAANAFEPELRHQHQLLISNVLAQSEALMKGRTFAEAKKQLTDKGMDDKKADFIAPHRVFTGNRPSITFVYDKLTPYALGRLIALYEHRVFVEGVLFRINSFDQWGVELGKELATGLLPVVEGKESAEGHDSSTQGLVAALAKLAK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRB1_MERUN
Sequence: ISALVSFLPILMHWWRAENDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKK
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  This receptor binds epinephrine and norepinephrine with approximately equal affinity.  Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity).  In dorsal pons neurons, involved in the regulation of sleep/wake behaviors (By similarity).
What are the official names of this protein?
Beta-1 adrenergic receptor, Beta-1 adrenoreceptor, Beta-1 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Colocalizes with RAPGEF2 at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity).
Protein: CAIT_SHISS
Sequence: MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURE_ACISJ
Sequence: MNALHTLTTLQEAVDWLRQRVTGTLQTDSRLIQPGDGFIAWPGAATDGRAHVGDAVARGAAACLVECEGVEPFALAGDHIAALRGLKAATGMIASEWFGHPTQRLQVLAVTGTNGKTSTAWWLADALNQLSKEELPALAGCALVGTLGMGVPPALQTTGMTTPDPVRLQRAFAQFAEAGHRACAIEASSIGLAEHRLDGTRIHVALFTNFTQDHLDYHPGMAAYWQAKRALFDWPGLRAAVVNVDDPQGAALHAELQGSDLDLWSISLQGPARLQAKHIVHTGAGLALTVAEGAHTEVLQTQVIGLYNVSNLLGVIAGMRALGVPLAQALQACARLRPVPGRMEQLAAAGQPLVAVDYAHTPDALHQALAALKPVAAQRGGRLWCVFGCGGNRDAGKRPLMGAVAQREADEVIVTSDNPRGEEPQSIIHQILLGTIAGTSVRAEVDRAAAIAQALAEAGANDVVLIAGKGHEDYQEAAGQRVPFSDMAHARAALARRGGVA
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPE_SALPK
Sequence: MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQTWDEYTDKTAEVLAPLGINVTGIHRVADPLAAIEKAEIIIVGGGNTFQLLKESRERELLAPVADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALDLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGEEAVALEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1259_AQUAE
Sequence: MMKRFVALSMAIFSLSFAQDVDEKIKALEEQIESLQKELQELKKAKEETEVLKEEFRKLRLEIVMPEAYKPYAGLGPAASKVYQVKKGVSIGGYGELHYINNPDNDPSSIIDLKRLILYFGYSFTENLKFNSEIEIEHAFVEGGEESGELAVEFAYLDYNFSPKFGLRGGMLLIPVGIVNELHEPPTFPTVDRPYLERNIIPTTWSENGIGIYGDTDLISYRAYIVNGMKAEEGEFKASAPLKKLRQNGGEAVSDSLAFTGRIDFKLPNNLTVGASTFISGVQNEDGKNLGNIYLFSPHLWWQYAGWDVRFVGAYATVSDAEKITLELSSATCDKSTCNVFPKRMQGFYLQVAYNILRHFDTEQELYVFGVYENYDTHASVPSGYEKPKGSEVQIFNFGISYKPHPLVALKADYVREDYKDKKDNDIYRAAITWMF
What are the official names of this protein?
Uncharacterized protein aq_1259.
Protein: GRAS_STAA3
Sequence: MNNLKWVAYFLKSRMNWIFWILFLNFLMLGISLIDYDFPIDSLFYIVSLNLSLTMIFLLLTYFKEVKLYKHFDKDKEIEEIKHKDLAETPFQRHTVDYLYRQISAHKEKVVEQQLQLNMHEQTITEFVHDIKTPVTAMKLLIDQEKNQERKQALLYEWSRINSMLDTQLYITRLESQRKDMYFDYVSLKRMVIDEIQLTRHISQVKGIGFDVDFKVDDYVYTDIKWCRMIIRQILSNALKYSENFNIEIGTELNDQHVSLYIKDYGRGISKKDMPRIFERGFTSTANRNETTSSGMGLYLVNSVKDQLGIHLQVTSTVGKGTTVRLIFPLQNEIVERMSEVTNLSF
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Functions as a sensor protein kinase which phosphorylates GraR through the auxiliary protein GraX.  In turn, GraR up-regulates many genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Sensor protein kinase GraS, Glycopeptide resistance-associated protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL16_RUBXD
Sequence: MLVPRKLKWRKPQRGRMKGRAKGGTEVQFGEYGLQALEPAWITNRQIEAARIAMTRKIRRGGKVWINIFPHKPVTKKPAETRMGSGKGSPEEYVAVVKPGRVMFEMSGVGEELAREAMRLAAQKLPIKTRFLVRGGGS
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ETFA_MYCLE
Sequence: MAEALVLVEHTEGALKKVSAELITAARVLGEPAAVVVGTPGTSAPLVDGLKTAGAAKIYVAESDAADKYLITPVVDVLAALAESSAPAAVLLAATADGKEIGGRLAARIGSGLLVDVVDVREGAVGVHSVFGGVFIVEAQANGDTPVITVRAGAVEAQPAEGAGEQVSVEVPAPAENATKITARAPAVVDNRPDLTEATVVVSGGRGVGSADNFSVVEALADSLGAAVGASRAAVDSGYYPGQFQIGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADFGVVGDLFKVAPQLTDGIKARKG
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases.  It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, Alpha-ETF, Electron transfer flavoprotein large subunit, ETFLS.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: Y1098_BARBK
Sequence: MTTDPKMLELLVCPITGGNLSFNRKTQELISLKAKLAYPIRDGVPIMLASEARPL
What are the official names of this protein?
UPF0434 protein BARBAKC583_1098.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: MURD_STRMU
Sequence: MKHVKNFENKKVLVLGLARSGEAAARLLAKLGAIVTVNDGKPFDENPSAQALLEEGIKVICGSHPLELLDEAFAYMVKNPGIPYTNPMVVRALEKNIPVITEVELAYLISEAPIIGITGSNGKTTTTTMIADVLNHAGQSARLSGNIGFPASEVAQPVTEKDILVMELSSFQLMGTESFHPHMAVITNLMPTHIDYHGSFENYIEAKWNIQKNMTKEDFLVLNFNQDLAKDLANQTQAKIIPFSTKEKVDGAYLDGQMLCFKGQAIMSASELGVPGSHNVENALATIAVAKLSGVSNEAIRETLIHFGGVKHRLQSLGNIAGVKFYNDSKSTNILATQKALSGFDNSKVILIAGGLDRGNEFDELVPDIKGLKKMIILGESAPRLKHAAVQAGVTYLNAKDVAQATRIAFQEASPGDVVLLSPANASWDMYKNFEVRGDEFITTFKSLKGE
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_FRATN
Sequence: MLGYILWTSLYVLLIVIPLILVVAYYTYAERKVIGYMQDRIGPNRVGSFGLLQPIFDALKLFLKEIIVPTNSNRYLFFIAPILAFAPAYAAWAVIPFSKGVVLSDMNLGLLYILAMTSFSIYGIVIAGWASNSKYSLFGALRAGAQVISYELAMGFAIVGVVIAAGSMGITGIIEAQSGGIWHWYFIPLFPLFIVYFIAGIAETNRAPFDVVEGESEIVAGHHIEYTGSRFALFFLAEYANMILISILTSIMFLGGWNSPFQATALESIFGFVPGVVWLFAKTGIFMFMFLWVRATYPRYRYDQIMRLGWKIFIPLTFVWVVIVACMVRLGVGPWW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.