PharMolix/UniProtQA huggingface dataset:
Protein: TGT_NITMU
Sequence: MKFQLHRTDGLARRGTLSLTHGVVETPAFMPVGTYGAVKTMSPADLQVINAHIVLGNTFHLWLRPGLQVIEAHGGLHRFMGWDGPILTDSGGFQVFSLGVLRKITEQGVKFKSPVNGDTCFLTPEESMRIQYVLNSDIVMIFDECTPYPADERAVGESMELSLRWAERSRQAHDEGGNRNGLFGIVQGGMYEKLRDESLAGLLDIGFDGYAIGGLSVGEPKADMRRILRHTAPGLPAGKPRYLMGVGTPADIVDAVAQGMDMFDCVLPTRNARNGWLYTRTGVIKLRNSQYRLDTRPADEQCTCYTCRHFSRAYLHHLQRTGEILGARLNTLHNLYYYQQLMGEIRTAIENGQFQEYAQAFQAQTAS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: BSK3_ORYSJ
Sequence: MGGRVSKAVACCCCRSQHHGVVVESSEKTAEEDHGESYELPAFQEFSFEQLRLATSGFAVENIVSEHGEKAPNVVYKGKLDAQRRIAVKRFNRSAWPDPRQFLEEAKSVGQLRSKRLANLLGCCCEGDERLLVAEYMPNDTLAKHLFHWEAQAMKWPMRLRVVLYLAEALEYCTSKGRALYHDLNAYRVLFDDDCNPRLSCFGLMKNSRDGKSYSTNLAFTPPEYMRTGRITPESVIYSFGTLLLDVLSGKHIPPSHALDLIRDRNFNMLTDSCLEGQFSNEEGTELVRLASRCLHYEPRERPNVRSLVQALAPLQKDLETPSYELMDIPRGGATSVQSLLLSPLAEACSRKDLTAIHEILEKTGYKDDEGTANELSFQMWTNQMQDTLNSKKKGDNAFRQKDFSSAIDCYSQFIEVGTMVSPTIYARRCLSYLMNDKAEQALSDAMQALVISPTWPTAFYLQAAALLSLGMENEAQEAIKDGCAHETSSSSGH
What is the function of this protein?
Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of BRI1.
What are the official names of this protein?
Probable serine/threonine-protein kinase BSK3, Brassinosteroid-signaling kinase 3, OsBSK3, Receptor-like cytoplasmic kinase 173, OsRLCK173.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Plasma membrane localization is required for its function in the regulation of brassinosteroid signaling.
Protein: SYA_ACIAC
Sequence: MTKPTPPSSVADIRKSFLDFFASKGHTVVPSSPLVPGNDPTLMFTNSGMVQFKDVFLGTDKRPYVRATSVQACLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRDSLKWAWELLTEVYGLPKERLLATVYAEDDEAYDIWTKEIGLPPERVIRIGDNKGGRYKSDNFWMMADTGPCGPCSEIFYDHGPHIPGGPPGSPDEDGDRFIEIWNNVFMQFDMAEDGSVTPLPAPCVDTGMGLERLAAILQHVHSNYEIDLFAALIQAAARETGTADLANPSLKVIADHIRATAFLVSDGVIPSNEGRGYVQRRIVRRAIRHGYKLGRKTPFFHSLVKDLVAQMGDAYPKLREQEQRITEVLKAEEERFFETLANGMDLLDSALDIQLASKALQNKTLRWFASEGREEKLVSFKDDVQVAEAVLISDELRSTEYMQRLKETVPGLNEVKTLHSVIRDWSGLTLPGDLAFKLHDTYGFPLDLTNDVCRERGVTVDEDGFKAAMDRQKAQARAAGKFKMDKALEYGGEANRFSGYDGLTESAKIVAIYVDGTSAQALEAGQNGVVVLDNTPFYAESGGQVGDQGVIHAGGARFAVDDTLKIRADVYGHHGRLESGTLRVGDAVQAEVDAALRAATMRNHSVTHIMHKALREVLGSHVQQKGSLVNAERTRFDFAHNAPVTDAQIREIERRVNEEILANTPTGARVMDIESAQKTGAMMLFGEKYGETVRVLDIGTSRELCGGTHVARTGDIGLFKVVGESGVAAGVRRIEAVTGAGALAYLQQLEDTVAKAAGALRAPAAEITGRIGQALEQVKALEREVAALKGKLASSQGDELAGQAVDVKGLKVLAATLPGADAKTLRDTMDKLKDKLKSAAIVLAAVDGAKVQIAAGVTPDAMAKVKAGELVNFVASQVGGKGGGKPDMAMAGGTDAAALPAALASVAAWVGERA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRTP_HHV2
Sequence: MAAAPPAAVSEPTAARQKLLALLGQVQTYVFQLELLRRCDPQIGLGKLAQLKLNALQVRVLRRHLRPGLEAQAAAFLTPLSVTLELLLEYAWREGERLLGHLDTFATTGDVSAFFTETMGLARPCPYHQQIRLETYGGDVRMELCFLHDVENFLKQLNYCHLTTPPSGATAALERVREFMVAAVGSGLIVPPELSDPSHPCAVCFEELCVTANQGATIARRLADRICNHVTQQAQVRLDANELRRY
What is the function of this protein?
This protein may affect translocation of the virus glycoproteins to membranes.  It is involved in capsid maturation.
What are the official names of this protein?
Processing and transport protein, Infected cell protein 18.5, ICP18.5 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae PRTP family.
Protein: RL4_CHLFF
Sequence: MVLLSKFDFFGNKAGEVELPDAFFAQEGNGLQLVKDYIVAIRANKRQWSACTRNRSEVSHSTKKPFRQKGTGNARQGCLAAPQFRGGGIVFGPKPKFDQHVRINKKEKRAAIRLLLSQKIQTNRLIVADDSVFTKSLTAPKTKEALRFLKSCNVECRGVLFIDDLNHAQNNEGLRLSLRNLPAVRGFAYGMNVNGYDLVSARNIVISEKALTGLVGHLTSGTKD
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: LOLB_SHESW
Sequence: MNNLKRFTESIFSCIALSTLLFLGGCQTLPPADDLTPITVSHPDQAKAWELQGKLAIKTPEDKLSANLYWRHSEERDELTLTTMLGTTVLTLEATPNSAHLHIDGKDFKDNNAQDLLERVSGWSIPLADLPLWITGQIGSQDRVLSRDSKANPKQLINDQTPPSWVVEFLSWQLQSGAHIPHQLKLERGDLQLKLQINQWQALGKATIMIGEKP
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YEAL_ECOL5
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFPWIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CPNT_MYCTU
Sequence: MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAGCAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNYSLAEAMSDVAGRAAPLPAPPPSGCVGVGAPPSAVGGGGGAPKGWGWVAPYIGMIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIRAQQLPEAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEAVITAMADHAGKQWDRFLHSNPVGVVIDGTGQQLKGFGEEAFGMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLIHWDEWTTNPNEALGKTVFDAATLALPGGPLSKLGSKGRDILAGVRGLKERLEPTTPHLEPPATPPRPGPQPPRIEPPESGHPAPAPAAKPAPVPANGPLPHSPTESKPPPVDRPAEPVAPSSASAGQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVESAPATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHDGASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGEGWHRLSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPYTQERYQERFNSVGPWGQQYSNFPPNNGAVPGTRIAYTNLEKFLSDYGPQLDRIGGDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQNEMRKVEELIRRGVLRQ
What is the function of this protein?
Has a dual function in uptake of nutrients and induction of host cell death.  The N-terminal domain (NTD) forms an outer membrane channel and is used for uptake of nutrients across the outer membrane.  The secreted C-terminal toxic domain (TNT) acts as a glycohydrolase, which hydrolyzes the essential cellular coenzyme NAD(+) in the cytosol of infected macrophages, leading to necrotic host cell death.  Both functions are required for survival, replication and cytotoxicity of M. tuberculosis in macrophages.
What are the official names of this protein?
Outer membrane channel protein CpnT, Channel protein with necrosis-inducing toxin.
What are the subcellular locations of this protein?
[N-terminal channel domain]: Cell outer membrane. SUBCELLULAR LOCATION: [Tuberculosis necrotizing toxin]: Secreted. Cell surface. Host cytoplasm, host cytosol. Note=Secreted into the cytosol of infected macrophages while the bacteria are still confined to the phagosome. Access to the macrophage cytosol depends on the ESX-1 / type VII secretion system (T7SS).
Protein: RSMF_SHIFL
Sequence: MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTTEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASWVKVLHANISRCGISNVALTHFGGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEAVCRWLKETYPDEVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKDREAGQIRQAAASVGLNWDGNLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIAHASPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTSNA
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Putative ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_SYNC1
Sequence: MNIKQLGWNAHFESHFENYRGQDLVPARVIRVGGGFYTLLGADGEQTATLAGQLRHGSTQDALPAVGDWVGIDSPQEGGIRIHAILPRQTALKRATVSNRKGLVEKPGVPQVLAANVDIAIIVCGLNRDYNPRRIERYLTLVHESGAMPLIVLNKSDICPETQARRAEIESIAFGTPVLVTSAQCGDGLDELASHLKAGSTLVLIGSSGAGKSTLLNRLACAEHQQTSEISAAVGKGMHTTTHRELFPLPGGALVIDTPGLRELHLWGESEAGLASTFPEVIGFAAQCRFSDCQHDQEPDCGIRQALHDGTLDPARLESYLKQRAEIASATLQSELAAQVAQKRKRKTIPRQGKRWRREHGDGQ
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAJD_ECOLI
Sequence: MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTVHHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYNPFADLKAMMNKKK
What are the official names of this protein?
Putative HNH nuclease YajD.
What is the protein family that this protein belongs to?
Belongs to the HNH nuclease family.
Protein: ATPF_STRPC
Sequence: MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDEAKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDDLGEA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NIKE_STAAN
Sequence: MIELKHVTFGYNKKQMVLQDINITIPDGENVGILGESGCGKSTLASLVLGLFKPVKGEIYLSDNAVLTIFQHPLTSFNPDWTIETSLKEALYYYRGLTDNTAQDQLLLQHLSTFELNAQLLTKLPSEVSGGQLQRFNVMRSLLAQPRVLICDEITSNLDVIAEQNVINILKAQTITNLNHFIVISHDLSVLQRLVNRIIVLKDGMIVDDFAIEELFNVDRHPYTKELVQTFSY
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import system ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LPXD_RHILO
Sequence: MTDPVFFAPSRRYTAAEVANLTGSVLVDSGQSDVSIEALAPASEGGANALVFVDGRRNSALMPSLRAAAVLCPAEFANKAPSSVAVLIHPRPQQAFALVGRLLFPTAATPGPMTSETGVSAHAHIDPTAHVEAGAIIEAGVVIGPGVSIGSGTVIAPNAVIGQSCQIGRDGYVGPGASIQYALIGNRVIIHGGARIGQDGFGFVGGAKGPERVPQIGRVVIQDDVEIGSNSTVDRGAMSDTIIGQGTKIDNLVQIAHNVRIGRNCIVAGLSGISGSVVVGDNVTMGGGVGLADHLTIGSGAKLAARSGFMSNVPAGEIWGGYPAQPMAEAMREIAMLRTMARARKQGKDNG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: FAR9_LOBRE
Sequence: GHGGASNYVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-9, FMRFa-9.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS3_BURP1
Sequence: MNAEAKPGDWLGKVRWDANGLVPVIAQDAATNDVLMFAWMNRDALAKTIELKRAVYYSRSRQRLWFKGEESGHVQHVHEVRLDCDEDVVLLKVEQVEGIACHTGRRSCFFQKFEGTVDDGEWVAVDPVLKDPEHIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMF_SERP5
Sequence: MVSYVPEIPLREPVTVEKKKSFPQQKSGLHPRNRHRSRYDFPALIASCPALEPFVKPNAWGDISVDFADPAAVKMLNRALLQHFYGIEHWDIPADYLCPPIPGRADYLHHLADLLATSNDGEIPRGKGVAILDVGIGANCIYPIVGLREYGWRFTGSEIDPVSLNSAKMIVEMNPTLRNSVRLRLQKQPEFIFNGIIGVAEKFDATLCNPPFHGSEQEAQASTRRKLHKLGKGEVADKPVQNFGGKNNELWCEGGEEAFVRKMVEESVSKAQNCLWFTSLISKHTTLPSIYHAAKLAGVAEVRTIEMAQGQKISRFVAWTFHDAEQQAAWAAERWR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH603_BRADU
Sequence: MSAKEVKFGVNARDRMLRGVDILANAVQVTLGPKGRNVVLDKSFGAPRITKDGVAVAKEIELDDKFENMGAQMVREVASKAADAAGDGTTTATVLAAAIVREGAKSVAAGMNPMDLKRGIDLAVEAVVADLQKNSKKVTSNDEIAQVGAISANGDQEIGKFLADAVKKVGNEGVITVEEAKSLETELDVVEGMQFDRGYISPYFVTNADKMRVEMDDAYILINEKKLSSLNELLPLLEAVVQTGKPLVIVAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLQDIAILTGGQAISEDLGIKLENVTLNMLGRAKKVMIDKENTTIVNGAGKKADIEARVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKERKDRVDDAMHATRAAVEEGIVPGGGVALLRASEQLKGLRTENDDQKTGVEIVRKALSWPARQIAINAGEDGSIVVGKVLDNEQYSFGFDAQTGEYSNLVSKGIIDPAKVVRIAVQNASSVAGLLITTEAMVAELPKKATAGPAMPAAPGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUMC_SALTY
Sequence: MVTVRREKDSMGAIEVPADKLWGAQTQRSLEHFRISTEKMPVSLIHALALTKRAAAKVNQDLGLLAAEKASAIIQAADEVLAGKHADEFPLAIWQTGSGTQSNMNMNEVLANRASEILGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALREHLIPQLSALTDTLRDKSHAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLRHIEHSLPHVAELALGGTAVGTGLNTHPEYARRVAEELATITAAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEIAIPENEPGSSIMPGKVNPTQCEAVTMLCCQVMGNDVAINMGGASGNFELNVYRPMVIHNFLQTVRLLADGMESFNKHCASGIEPNRERITQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKASAVALGYLSDEEFDAWVRPELMVGSMTPGR
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM10A_BOVIN
Sequence: MSSEMLPAFSETCNVERQKNLSEDGEQNQKPGSSERFQPISKRQMKKLMKQKQWEEQRELRKQKRKEKRKRKQLERQCQPESNSDGSDRKRIRRDVVHSPLRLIIDCSFDSLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSEFIQKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDHGIDHAQLPLGNFVKMNSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDQACESCSHDKKFARVEGGLNSDSSEEENRHELDSTHEEEKQDKENSTESTVNSVPH
What is the function of this protein?
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs.  Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs.
What are the official names of this protein?
tRNA methyltransferase 10 homolog A, RNA (guanine-9-)-methyltransferase domain-containing protein 2, tRNA (guanine(9)-N(1))-methyltransferase TRMT10A.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: YOA2_SCHPO
Sequence: MDKKIADLLQELQSSSNVTSNQLENVDKSSIPLSKARKPSDFELNNSIEDAEKIKTYPAALRYIFALNSRHPEKLQKLRKMKAMQERQERNWSLERQRLVQHFESKTKLQEILKPLSSDPKLKQPSNCLNDQTNNDSAQTLDDNRALQEFDEQVVQLTNRMYKEQLAILADLKIPLFLSVNNDEELSEDQKRLLQLLQDLLGA
What are the official names of this protein?
Uncharacterized protein C557.02c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDHM_TRIEI
Sequence: MLLKSTTRHIRIFAGTVENNELVPDDQALTLDIDPDNELNWNDTAVEQVYRKFDELVESYSGSDLTEYNLRCMGSDLEHFVRSLLQSGEISYNLGSRVNNYSLGLPRVDVDAEAK
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit M, NAD(P)H dehydrogenase I subunit M, NDH-1 subunit M, NDH-M.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhM subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLN1B_PSEAE
Sequence: MSYKSHQLIKDHDVKWVDLRFTDTKGKQQHVTMPARDALDDEFFEAGKMFDGSSIAGWKGIEASDMILMPDDSTAVLDPFTEEPTLILVCDIIEPSTMQGYERDPRNIAKRAEEYLKSTGIGDTVFVGPEPEFFIFDEVKFKSDISGSMFKIFSEQASWNTDADIESGNKGHRPGVKGGYFPVPPVDHDHEIRTAMCNALEEMGLVVEVHHHEVATAGQNEIGVKFNTLVAKADEVQTLKYCVHNVADAYGKTVTFMPKPLYGDNGSGMHVHMSISKDGKNTFAGEGYAGLSETALYFIGGIIKHGKALNGFTNPSTNSYKRLVPGFEAPVMLAYSARNRSASIRIPYVSSPKARRIEARFPDPAANPYLAFAALLMAGLDGIQNKIHPGDAADKNLYDLPPEEAKEIPQVCGSLKEALEELDKGRAFLTKGGVFTDEFIDAYIELKSEEEIKVRTFVHPLEYDLYYSV
What is the function of this protein?
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_GLOC7
Sequence: MERNTNPNRQPVELNRTSLYLGLLLVAVLGILFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: FPG_CROS5
Sequence: MPELPEVETVCRGLNQLTFGQTIRGGKVLLPRTLAYPVSIEEFLEQINNATFGQWQRRGKYLLVPLEEKKGWLGVHLRMTGQLLWVKQNEPLSRHTRLRLFCDRSKELRFVDIRTFGKVWWVPPNQPPETIITGLQKLGLEPFSNAFSLDYFIDKLKGRQRNIKTILLDQSVVAGIGNIYADEALFKSGIRPTTLGKELSQPQVKRLREAMIEVLKTAIEEGGTTFSDFRGVTGINGNYSGVAWVYGRHNQPCRVCGTPIERIKLGGRSSHFCPQCQPLGNKK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: ILVC_KLEP7
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVASGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKEFMTTLQTGDLGTAIAEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.