PharMolix/UniProtQA huggingface dataset:
Protein: RBL_DENCL
Sequence: SPQXETKASVGFKAGVKDYKLTYYTPDYKTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENHFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIAKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFQAVDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLGM1_TRYBB
Sequence: MQLQRLGAPLLKRLVGGCIRQSTAPIMPCVVVSGSGVFLTPVRTYMPLPNDQSDFSPYIEIDLPSESRIQSLHKSGLAAQEWVACEKVHGTNFGIYLINQGDHEVVRFAKRSGIMDPNENFFGYHILIDEFTAQIRILNDLLKQKYGLSRVGRLVLNGELFGAKYKHPLVPKSEKWCTLPNGKKFPIAGVQIQREPFPQYSPELHFFAFDIKYSVSGAEEDFVLLGYDEFVEFSSKVPNLLYARALVRGTLDECLAFDVENFMTPLPALLGLGNYPLEGNLAEGVVIRHVRRGDPAVEKHNVSTIIKLRCSSFMELKHPGKQKELKETFIDTVRSGALRRVRGNVTVISDSMLPQVEAAANDLLLNNVSDGRLSNVLSKIGREPLLSGEVSQVDVVLMLAKDALKDFLKEVDSLVLNTTLAFRKLLITNVYFESKRLVEQKWKELMQEEAAAQSEAIPPLSPAAPTKGE
What is the function of this protein?
Essential for RNA editing.  RNA editing in kinetoplastid mitochondria inserts and deletes uridylates at multiple sites in pre-mRNAs as directed by guide RNAs.
What are the official names of this protein?
RNA-editing ligase 1, mitochondrial, RNA ligase 1.
What is the protein family that this protein belongs to?
Belongs to the RNA ligase 2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PROA_NITMU
Sequence: MDIIDIKTYMHSIGREARAASRLIAKAETAAKNRALTQMAVAIKRDEQQLLAANARDVENAKERGLEAAMIDRLTLTPKSVASMAEGLLQIAALADPVGEISDLNYRPSGIQVGKMRVPLGVIGIIYEARPNVTADAAGLCLKAGNAAILRGGSEAIYSNQAIAACVREGLKTAGLPETAIQVIETTDRAAVGELVTMKEFVDVIVPRGGKGLIERISNEARIPVIKHLDGVCHIYIDEEADQEKAIRVADNAKTQRYGTCNTLETLLVHENIAGEVLPPLCRIYLDKGVELRGDPASQAIIPEMKEAREEDWYTEYLAPVLSVRVVSSLDQAIEHITIYGSQHTDSIITENYSNARRFLREVDSSSVMVNASTRFADGFEYGLGAEIGISTDKLHARGPVGLEGLTSQKFIVLGDGHIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAO1A_XENLA
Sequence: MPSTSRAGSLKDQDIAELFFRDDPEKLFSDLREIGHGSFGAVYFAHDASTREVVAIKKMSYSGKQSNEKWQDIVKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEIEIAAITHGALQGLAYLHSHNLIHRDIKAGNILLTEPGQVKLADFGSASIASPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEWSDFFRNFVDSCLQKIPQDRPTSDELLKNMFVLLERPETVLIDLIQRTKDAVRELDNLQYRKMKKLLFQEAHNGPAVETHEEEEEQEHGVGRTGTVNSIGSNQSIPSMSISASSQSSSVTSLPDASDDKSELDMMEGDHTVMSNSSVIHLKPEEENYPEEPEPRTRPSEPHSPPQVSRHKSHYRNREHFATIRTASLVTRQIQEHEQDSELREQMSGYKRMRRQHQKQLMALENKLKAEMDEHRLRLDKDLETQRNNFSAEMEKLVKKHQAAMEKELKSIANDEKKFQQHIQAQQKKELNNFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENFQHFQAEEEANLLRRQRQYLDLECRRFKRRMLLNRHNSEQDLVREELNKRQTQKDLEHAMLLRQHESMQELEFRHLNTIQKMRCELIKLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLDTTPKNEHKAVLKRLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHEREIHELEQRVSLHRGLLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMILSNLSPEAFSHSYPGASGWSHNPTGGPGPHWGHPMAGPPQAWGHPMQGGPQPWGHPSGSVQGVSRGSTMGVRNSPQALRRTASGGQTEQGMSRSTSVTSQISNGSRMSYT
What is the function of this protein?
Serine/threonine-protein kinase involved in various processes such as p38/mapk14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability.  Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of upstream MAP kinase kinases.  In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase TAO1-A, Thousand and one amino acid protein 1-A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_HYPBU
Sequence: MAHGPRYKVPRRRRREGKTNYYKRYVMVLSGKPRFVVRRTNQYIWVQVIIAKPQGDVTVAAAHSRELVKKYGWLGGTKNTPAAYLTGLLAALRALKAGITYAVLDIGLHRPTRGARVFAALKGALDAGLEIPHSEEVLPEEYRIRGEHIAKYAAMLKEQNPELYEKRFSLYLARGLNPEDLPQHFEEVKNKILEEYREVLEKVKAEAAVEA
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ACPM_HUMAN
Sequence: MASRVLSAYVSRLPAAFAPLPRVRMLAVARPLSTALCSAGTQTRLGTLQPALVLAQVPGRVTQLCRQYSDMPPLTLEGIQDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) (PubMed:27626371).  Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (PubMed:27626371).  Accessory protein, of the core iron-sulfur cluster (ISC) assembly complex, that regulates, in association with LYRM4, the stability and the cysteine desulfurase activity of NFS1 and participates in the [2Fe-2S] clusters assembly on the scaffolding protein ISCU (PubMed:31664822).  The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis.  This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner.  Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly.  Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5 (By similarity).
What are the official names of this protein?
Acyl carrier protein, mitochondrial, ACP, CI-SDAP, NADH-ubiquinone oxidoreductase 9.6 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NGFV3_DEMVE
Sequence: MSMLCYTLIIAFLIGIWAAPKSEDNVPLGSPATSDLSDTSCAQTHEALKTSRNTDQRHPAPKKAEDQELGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQSVEFLENEDALNRNIRSKRENHPVNDHGEYSVCDSVSVWVNKTTATDIKGKPVTVMVDVNLNNHVYKQYFFETKCKNPNPVPSGCRGIDSRHWNSYCTTTQSFVKALTKEGNQASWRFIRIDTACVCVISRKTGNF
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor 3, v-NGF-3, vNGF-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14_GLUOX
Sequence: MAKVSAVNRNNHRAALVKRDKEKRTALKNIIKDRTLSVEDRFDATLKLAQMPRNGSATRVRLRCKLSGRPRANYRKFELSRIALRDLASAGQIPGMVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ATPF_NEUCR
Sequence: MASRLARTAVGAARLRPSVVPRVLPALSTVASPRYSSGVPSEDPKTKAQSIIDSLPGSNLMSKTAILSSAAGLSIYALSNEYYVVNEETVVAFCLLSVWGGLIKFGGPLYKKWADEQSDKIKNILNSARADHTQAVKTRIGDVKQMSGVIDITKTLFAVSKETAKLEAEAYELEQRTALAAEAKTVLDSWVRYESQVKQRQQKELAQTVIAKVQKELENPKVLKQILEQSVADVEKIVSKA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/atp6 static relative to the rotary elements (By similarity).
What are the official names of this protein?
ATP synthase subunit 4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase B chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: HTPX_PSEAB
Sequence: MMRILLFLATNLAVLVIASITLKLLGVDRFTGQNYGSLLVFCAVFGFAGSLVSLFISKWMAKMSTGTEVISQPRTRHEQWLLQTVEELSREAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIFGNFVDKAILKNEDGPGIGYFVATIFAELVLGILASIIVMWFSRRREFRADAAGAHLAGTGAMIAALQRLRSEQGVPVQMPDTLNAFGINGGLKHGLAGLLMSHPPLEDRIEALRASAR
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_CLONN
Sequence: MNVKPEEITSIIKKQIESYEHKIQTVDSGTIIQIGDGIARVYGIEDCMEGELLEFPNDVYGMALNLEQDNVGCVLLGPEKGIKEGDVVKRTGRVVEVPVGEALIGRVVNALGQPLDGKGPIKCTQTRAIELEAPGVIERKSVKEPLQTGIKAIDSMVPIGKGQRELIIGDRQIGKTAIAIDTIINQKDKNVKCIYVAIGQKQSTVAHIVNTLTEMGAMDYTIVVSSTASDSAPLQFLSPYSGCSMAEYFMLKGEDVLIIYDDLSKHAVAYRTMSLLLRRPPGREAYPGDVFYIHSRLLERAAKLSDKLGGGSITALPIIETLAGDVTAYIPTNVISITDGQIFLESELFYAGQKPAVNAGISVSRVGGNAQIKAMKQVSGTLRLELAQYRELAAFAQFGSDLDNSSKERLEKGKRLVEILKQDQYKPMPVEKQIIILYAAVNNYLSDIKVSDIRTFEREFLEYVDTHYRDLGQKILDKKELTDDIKGELNTAIQEFKKVFLA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CYB_PLAGA
Sequence: MNYYSINLAKAHLLHYPCPLNINFLWNYGFLLGIVFFIQILKGVLLALVILQKLSYAYYSVQHILRAIMDGWCFRYMHATGASFVFILTYLHILRGLNYSYSYLPLSWISGLMIFLISIVTAFYGYVLPWGQMSFWNTTVITNLLYLFRTCFMDCGGYLVSDPTLKRFFVFIYFPFIALCQSLFGILPLSHPDNAITVDRYATPLHIVPEWYFLPFYAMLKTIPNKTAGLLVMLASLQILFLLAEQRNLTTLIHFKFAFGAREYSVPTICYMSSMLIWIGCQLPQILHFIWSFIYYIILF
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLYA_STAA8
Sequence: MSYITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFVDVTESIAIDRAKALFGAEHVNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHLTHGAPVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMILCKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKDEEKLQQAKERVAKLTAEYPLYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SULA_ECO7I
Sequence: MYTSGYAHRASSFSSAASKIVRVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: RS21_CAUVC
Sequence: MVGLSNGEIPLVQIFVRDNNVDQALKALKKKMQREGSFREMKRHVHYEKPSEKRARQKAEAVRRARKLARKRAQREGLLPMPKKPGR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: NRDR_BACHK
Sequence: MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREEFNKEKILRGLIKACEKRPVSLRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RBL_PORUM
Sequence: MSQSVESRTRIKSERYESGVIPYAKMGYWDADYVIKDTDVLALFRITPQPGVDPIEASAAIAGESSTATWTVVWTDLLTACDLYRAKAYRVDPVPNVADQYFAYIAYDIDLFEEGSIANLTASIIGNVFGFKAVKALRLEDMRMPVAYLKTFQGPATGLIVERERMDKFGRPFLGATVKPKLGLSGKNYGRVVYEGLKGGLDFLKDDENINSQPFMRWRERYLYSMEGVNKASAAAGELKGHYLNVTAATMEDMYERAEFSKVVGSVICMIDLVIGYTAIQSMAIWARKNDMILHLHRAGNSTYSRQKNHGMNFRVICKWMRMAGVDHIHAGTVVGKLEGDPLMIKGFYNTLLESETDINLPQGLFFAQNWASLRKVVPVASGGIHAGQMHQLLDYLGDDVVLQFGGGTIGHPDGIQAGATANRVALESMVMARNEGRDYVAEGPQILRDAAKTCGPLQTALDLWKDISFNYTSTDTADFVETPTANV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL13_THET8
Sequence: MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PANC_PSEPK
Sequence: MNTVKTVRELRAAVARARGEGKRIGFVPTMGNLHSGHAALVTKAAQRADFVVASIFVNPLQFGANEDLDKYPRTLAADQERLVQAGCNLLFAPTVEEMYPDGMSVQTRVSVPQLSEGLCGASRPGHFEGVATVVNKLFNMVQPDLAVFGEKDYQQLAVIRAMVRDLNMPIQIIGEPTVRAEDGLALSSRNGYLTPEQRTAAPALYRTLQHIAAGIGRGQRDFAALVAEGQAQLSAAGFRPDYLEVRHAVSLRPAVINDRDLVVIAAAYLGNTRLIDNLYLHLEEKTA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH601_RHILO
Sequence: MSAKEIKFATDARDRMLRGVEILTNAVKVTLGPKGRNVIIDKAYGAPRITKDGVTVAKEIELADKFENMGAQMVREVASKTNDLAGDGTTTATVLAASILREGAKLVAAGMNPMDLKRGIDQAVAAVVVEIKAKAKKVKSSAEIAQVGTIAANGDATVGAMIAKAMDKVGNDGVITVEEAKTAETELDVVEGMQFDRGYLSPYFVTNADKMRVELEEPYVLIHEKKLGNLQAMLPILEAVVQSGRPLLIISEDVEGEALATLVVNKLRGGLKVAAVKAPGFGDRRKAMLEDIAVLTAGQMISEDLGIKLENVTIEMLGRAKRVLIEKDTTTIIDGAGTKATIQARVAQIKGQIEETTSDYDKEKLQERLAKLSGGVAVIRVGGVTESEVKEKKDRIDDALNATRAAVEEGIVPGGGVALLRARSALSGLNGANADVTAGISIVLRALEAPIRQIAENSGVEGSIVVGKLADSKDHNLGFDAQNETYVDMIKAGIVDPAKVVRTALQDAGSIAALLITAEAMITDIPAKDAAPAGGGGGGMGGY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG14_MOUSE
Sequence: MLSILILAATAAGLVILLFQRLWTVLGPHHVTPRESLRLLIVAGSGGHTTEILRLVGSLSNAYSPRHYVIAESDEMSAKKIHSLEELSRAQNDSTTEYPKYHLHRIPRSREVRQSWLSSVFTTFYSMWFSFPLVLRIKPDLVLCNGPGTCVPICVSALLLGILGVKKVIIVYVESICRVETLSLSGKILRHLSDYFIVQWPTLKEKYPKSVYLGRIV
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway.  Anchors the catalytic subunit ALG13 to the ER (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit ALG14 homolog.
What is the protein family that this protein belongs to?
Belongs to the ALG14 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein.
Protein: YDIB_ECO5E
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDKFFDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENKSLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: FABH_CAMHC
Sequence: MKNAAMLSIGAYVPPYELSNFDLEKMVETSDEWIVKRTGIHTRHIAKNETAGDMAAKAADLAISRSGISKEEIDAIICATITPDFFCMPSTACITAEKLGLNKGITAFDISAACSGFIYLLEIGSALIKSGAKKNVLIIGTEKLSSIVDWKDRATCVLFGDGAGAAVLSCMDNKNNGISKPYGIIDIHTASDGNKAELLMTPTKNSNIKDIADENLGFLHMKGNEVFKIAVQTLSNDVVKILKKNNVKPEEIDLFVPHQANFRIIEAVKNRLNFTDNQCVVTVGKYGNTSSASIPIALNEAYENGRLKNGSLILLDAFGGGFTWGSALIRFGL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEACT_AGRFC
Sequence: MTSGEQAKTPLQAPILLTNVKPVGFGKGASQSSTDILIGGDGKIAAVGSALQAPADTQRIDAKGAFISPGWVDLHVHIWHGGTDISIRPSECGAERGVTTLVDAGSAGEANFHGFREYIIEPSRERIKAFLNLGSIGLVACNRVPELRDIKDIDLDRILECYAENSEHIVGLKVRASHVITGSWGVTPVKLGKKIAKILKVPMMVHVGEPPALYDEVLEILGPGDVVTHCFNGKSGSSIMEDEDLFNLAERCAGEGIRLDIGHGGASFSFKVAEAAIARGLLPFSISTDLHGHSMNFPVWDLATTMSKLLSVDMPFENVVEAVTRNPASVIRLDMENRLDVGQRADFTVFDLVDADLEATDSNGDVSRLKRLFEPRYAVIGAEAIAASRYIPRARKLVRHSHGYSWR
What is the function of this protein?
Esterase that catalyzes the deacetylation of acetyl-(R)-mandelate (in vitro).  Can also hydrolyze acetyl glycolate, but with lower efficiency.  Has very low N-acetyl-D-amino acid deacetylase activity with N-acetyl-D-serine and N-acetyl-D-threonine (in vitro).  Theoretical substrate docking studies suggest that other N-acetylated amino acids may optimally occupy the active site and may in fact be the physiological substrates.
What are the official names of this protein?
Deacetylase Atu3266.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Atu3266/EF_0837 deacetylase family.