PharMolix/UniProtQA huggingface dataset:
Protein: YAAB_SCHPO
Sequence: MPDPNRVLAGKKATLHNPNVSQQAKERAEDYIESHSSGQETGDYSAQAGGRDLDYEDLGDYDEDADFDNEEGLNVLGDESGFVDDPMKTGDLVEEDQLEGKNIENVRGGYKATMHNPNVSKQAKTRAQRALEEIDDETQA
What are the official names of this protein?
UPF0654 protein C22G7.11c.
What is the protein family that this protein belongs to?
Belongs to the UPF0654 (con-6) family.
Protein: YIHY_SALDC
Sequence: MLKTVHQKAGRHTRPVRAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLIAVVFALFAAFPMFSDVSIQLRHFIFANFMPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYAIDSALNTIWRSKRTRPKVYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRILPLLLSWISFWLLYSIVPTTRVPNRDALVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEADQP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRB_ECOBW
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_CYTH3
Sequence: MSRIGKLPVTLPEKVELSVSPSNLVTVKGPKGTLTQQVDVDIKVSVEDGKVVVARPTEQKRHKALHGLYRSLISNMVQGVSQGYKVELELVGVGYKATATNNILELSLGYSHGIFLKLPSEISASALTEKGKNPIVTLECIDKQLIGQVSAKIRSLRKIEPYKGKGVRFKGEVVRRKAGKTASK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: IPYR_PSEAE
Sequence: MSYSKIPAGKDLPNDIYVAIEIPANHAPIKYEIDKDTDCLFVDRFMATPMFYPANYGFIPNTLADDGDPLDVLVVTPYPVAPGSVIRARPVGVLHMTDEAGGDAKLIAVPHDKLSVLYKDVKEYTDLPALLLEQIKHFFENYKDLEKGKWVKVEGWGNADAARAEITKAVAAFQK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QPCT_BOIDE
Sequence: MAGERRDSKAAAFFCLAWALCLALPGFPQHVGGREDRADWTQEKYSHRPTILNATSILQVTSQTNVNRMWQNDLHPILIERYPGSPGSYAVRQHIKHRLQGLQAGWLVEEDTFQSHTPYGYRTFSNIISTLNPLAKRHLVVACHYDSKYFLPQLDGKVFVGATDSAVPCAMMLELARSLDRQLSFLKQSSLPPKADLSLKLIFFDGEEAFVRWSPSDSLYGSRSLAQKMASTPHPPGARNTNQIQGIDLFVLLDLIGARNPVFPVYFLNTARWFGRLEAIEQSLHDLGLLNNYSSERQYFRSNIRRYPVEDDHIPFLRRGVPILHLIPSPFPRVWHTMEDNEENLDKPTIDNISKILQVFVLEYLNLG
What is the function of this protein?
Responsible for the biosynthesis of pyroglutamyl peptides.  Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue.  Also catalyzes N-terminal pyroglutamate formation (By similarity).
What are the official names of this protein?
Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, QC, Glutaminyl-tRNA cyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the glutaminyl-peptide cyclotransferase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CBPA_ECOLC
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TBB5_RAT
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-5 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DAPA_PROMP
Sequence: MIPNNTKFSNPLFGRILTAMVTPFKKNGAVDYELAIKLSNYLCENGSDGIVLCGTTGESPTLTWAEQHNLFVAVKGSLNSRSKVIVGTGSNCTSEAIEATQKAYEFGADGALVVVPYYNKPPQEGLYKHFSSIANAASDLPLMLYNIPGRTGCNLLPTTVNKLMNFPNILSIKAASGRIEEVTELRAACGSKLSIYSGDDSLLLPMLSVGAVGVVSVASHIVGLQLKTMIESFQKGEISIALDIHEKLQPLFKALFETTNPIPIKAALELRGWQVGSPRNPLTPLIKEKRESLLQIIQNLSL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAGO4_CAEEL
Sequence: MPALPPVYTPSGAPSSVHAPPAVPPVPVPTQPLRSEYQTSNDACIKRLEELNIAPAAKLYPTPTEPGKCGVEAEIQTNVFGIEMHQDSLFYQYSVNITTELKNGKEVTFTKKGKDDFVVTERHDKCCAILFRALGDYEEFFKTSDSCLIYDGQSILFSNVDLFQGFREGAVKTKYMQLDGGEMDHKDLKSLPCIKLEVFPTKNPAVKFTREAVARRATDSNLDSVSLAYQQILELALTQPCLRNTARYVVFDHGKMFFIDPLGEGFEKCDVVDVGDGKQVVPGLKKTINFIEGPYGRGRSNPSVVIDGMKVAFHKNQPILDKLKEITTQPVEHGLKGLEKDRCAAVIKGLDCYSTYGGRERHHKIEGIHHEGARNARFELNDGGSCTVAQYFEDVYNITLRYPDTNLIVSKERGNINFYPMELLKISSHQRVQIPQLTSAQSQKTTKESAVLPDVRQRLILTGKNAAQISSDNEVLGKMGVSVCEDPLMVKGRSIPAVKLANAEIGANPINVKDNKWRANRFTRPATAPNVWAMYVVGTASTRITLDTLKKFADEFAAMCKSKGVNMPAPADISLIHMDAIESRLYDATKANCTFVFIITDDSITTLHQRYKMIEKDTKMIVQDMKLSKALSVINAGKRLTLENVINKTNVKLGGSNYVFVDAKKQLDSHLIIGVGISAPPAGTKYAMENKGVLNPNVIGYAYNAQHNQEFSGDFVLNSASQDTLAPIEDIVMHSLNEYQKFHDGGLPRRVIVYRTGTSEGNHGSIMAYEIPLARAAMRDFSPDIQLVYIVVSKDHSFRFFKPDLASLASRPQATSSTASRHSAMPAAPKAWDLNIAPGILVDSIVTNPACKQFFLNSHITLQGTAKTPLYTVLADDAKVSMTALEDITYKLCHLHQIVGLPTSLPTPLYVANEYAKRGRNLWNEAVALNNVPTVSGPEADRLKELTKSICYKASGDLTGRRVNA
What is the function of this protein?
Argonaute protein which is involved in the endogenous small interfering RNA (endo-siRNA) pathway and is required for RNA-mediated gene silencing (RNAi) in the germline (PubMed:17110334, PubMed:29791857, PubMed:30728462).  Interacts with secondary 22G-RNAs, which are RNA-dependent RNA polymerase-derived endo-siRNAs, typically 22 nucleotides in length with a 5'guanosine residue (PubMed:29791857).  Also interacts with the mRNA targets of 22G-RNAs (PubMed:29791857).  Associates with znfx-1 to mediate small RNA-directed transgenerational epigenetic inheritance of both germline- and soma-expressed genes (PubMed:29791857, PubMed:29769721).
What are the official names of this protein?
Argonaute protein wago-4, Worm-specific argonaute protein 4.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. WAGO subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasmic granule. Cytoplasm. Note=Co-localizes with znfx-1 in P-granules in germline blastomeres until the 100-cell stage (PubMed:29769721). During oocyte maturation, co-localizes with znfx-1 in liquid-like condensates in the cytoplasm called Z granules (PubMed:29769721). Localizes to cytoplasmic P- granules in germline blastomeres.
Protein: MSRQ_XANCP
Sequence: MAKKSVSVIAAKTAVHAAVLAPIALLGWQFWQVWQQGSDALGADPVAEIEHRTGLWALRLLLITLAITPLRQLTGQAVLIRFRRMLGLYAFFYASVHLTAYLWLDLRGFWTQIFEEIVKRPYITVGFTAWLLLVPLAITSTQGWMRRLKRNWGRLHMLIYPIGLLAVLHFWWLVKSDIREPALYAGILALLLGWRVWKRLSARRTTARHSAPPPATPR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CR1IC_BACTU
Sequence: MKLKNPDKHQTLSSNAKVDKIATDSLKNETDIELKNMNNEDYLRMSEHESIDPFVSASTIQTGIGIAGKILGTLGVPFPGQIASLYSFILGELWPKGKSQWEIFMEHVEAIINRKISTYARNKALTDLKGLGDALAVYHESLESWVGNRNNTRARSVVKNQYIALELMFVQKLPSFAVSGEEVPLLPIYAQAANLHLLLLRDASIFEKNGGLSASEISTFYNRQVERTRDYSYHCVKWNNTGLNNLRATNGQSWVRYNQFRKDIELMVLDLVRVFPSYDTLVYPIKTTSQLTREVYTDAIGTVDPNQALRSTTWYNNNAPSFSAIEAAVIRSPHLLDFLEKVTIYSLLSRWSNTQYMNMWGGHRLESRPIGGALNTSTQGSTNTSINPVTLQFTSRDFYRTESWAGLNLFLTQPVNGVPRVDFHWKFPTLPIASDNFYYLGYAGVGTQLQDSENELPPETTGQPNYESYSHRLSHIGLISGSHVKALVYSWTHRSADRTNTIEPNSITQIPLVKAFNLSSGAAVVRGPGFTGGHILRRTKSGTFGHIRVNINPPFAQRYRVRMSYASTTDLQFHTSINGKAINQGNFSATMNRGEDLDYKTFRTVGFTTPFSFSDVQSTFTIGAWNFSSGNEVYIGRIEFVPVEVTYEAEYDFEKAQEKVTALFTSTNPRGLKTDVKDYHIDQVSNLVESLSDELYLDEKRELFEIVKYAKQIHIERNM
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.
What are the official names of this protein?
Pesticidal crystal protein Cry1Ic, 81 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryII(c).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: ARGR_BACMK
Sequence: MNKGQRHIKIREIIANKEIETQDELVDILRNVGFNVTQATVSRDIKELHLVKVPLHDGRYKYSLPADQRFNPLQKLKRNLVDSFVKLDTAGHMLVLKTLPGNAHSLGALIDHLEWDEIVGTICGDDTCLIICRTPEDTGVVSDRFLNML
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTF3_HUMAN
Sequence: MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDDDDEVPDLVENFDEASKNEAN
What is the function of this protein?
When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER).  Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER.  BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II.  Required for the initiation of transcription.
What are the official names of this protein?
Transcription factor BTF3, Nascent polypeptide-associated complex subunit beta, NAC-beta, RNA polymerase B transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the NAC-beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The heterodimer with NACA is cytoplasmic.
Protein: PLSX_OLEA2
Sequence: MSNSVPVIAVDAMGGDHGPSIVVPGAVRAARENSLKLILVGDKDAISAELNRLPLDGVAYDIVHASQVAGMEEKPSDILRRKKDASVQVACRLVRSGDADGIVSAGNSGATVACGMFIMGRIPGVERPALASVMPTEKKPCVLLDVGANVDCKPYHLFQFGLMAEAFARDLLEIETPRVGLLSIGEEEGKGNSQVKEAYELLREAKNINFVGNIEGCDLFTGNVDVAVCDGFVGNVALKLSEGLASSLARLLKRELLTGIKAKIGTFLARDAFRRFARFVDYAEYGGAPLLGLQGIAIVCHGASNEKAIASAVGMAGTFVSKGTYHHLVETISANEELTSYGKAVKQ
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ATP6_SYNPW
Sequence: MVPSLLNLPFAELEVGQHLYWQIGNLNLHGQVFLSSWVVIGLLLLLVVSGTRKMERDPKGVQNLLEYLWDYLRELAREQIGEKAYRDWLPFVGTLFLFIFVCNWGGALIPWRLVELPNGELGAPTADINTTVAMALLVSLSYFYAGLSRKGLRYFEYYVEPTPIMLPFKIIEDFTKPLSLSFRLFGNILADELVVAVLAFLVPVLVPLPAMFLGLFTSAIQALIFATLAANYIGEAVHEEAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: KAD_BAUCH
Sequence: MRIILLGAPGSGKGTQAQFIMKKYGIPHISTGDMLRTTVNKESVLGKNIQAIIKLGNLVPDQLVIELVKERIIQYDCSKGFLLDGFPRTLTQAYAMEVAGINVDIVLILRIPDKIIINRIVGRMVHEPSGRIYHVTFNPPKQKGKDDITGENLIIRQDDKEDTVRHRLIGYHQQMIPIITYYNNANIRNIRCFTIDANCPISTLNEKIVRILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_SHESH
Sequence: MKHIRNFSIIAHIDHGKSTLSDRLIQECGGLSDREMAAQVLDSMDIERERGITIKAQSVTLDYKAQDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTALEMDMDVVPVLNKIDLPQADPERVADEIEDIVGIEAADAVRCSAKTGIGIKDVLEVIVAQIPSPEGDPEGPLQALIIDSWFDSYQGVVSLVRIKNGVLRKGDKFKVMSTGQNYNADRVGIFTPKQTDTTELKTGEVGFIIAGIKEIHGAPVGDTLTHAKHGADKPLAGFKKVKPQVYAGLFPISTDDYESFRDALNKLSLNDASLFFEPETSSALGFGFRIGFLGLLHMEIIQERLEREYNLDLITTAPTVVYEIVKTSGETIYVDNPSDLPAINNIEEMREPIVETNILVPKEYLGNVITLCVEKRGVQKNLVYHGNQVALTYELPMAEVVMDFFDRLKSTSRGYASLEYNFIRFEPADMVRLDILINGDRVDALAMIIHKGLIRSKGLALVNKMKELIPRQMFDIAVQAAVGSQIIARSSIKAMRKDVTAKCYGGDVSRKKKLLNKQKEGKKRMKQVGNVEVPQEAFLAVLKLND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GAI_ARATH
Sequence: MKRDHHHHHHQDKKTMMMNEEDDGNGMDELLAVLGYKVRSSEMADVAQKLEQLEVMMSNVQEDDLSQLATETVHYNPAELYTWLDSMLTDLNPPSSNAEYDLKAIPGDAILNQFAIDSASSSNQGGGGDTYTTNKRLKCSNGVVETTTATAESTRHVVLVDSQENGVRLVHALLACAEAVQKENLTVAEALVKQIGFLAVSQIGAMRKVATYFAEALARRIYRLSPSQSPIDHSLSDTLQMHFYETCPYLKFAHFTANQAILEAFQGKKRVHVIDFSMSQGLQWPALMQALALRPGGPPVFRLTGIGPPAPDNFDYLHEVGCKLAHLAEAIHVEFEYRGFVANTLADLDASMLELRPSEIESVAVNSVFELHKLLGRPGAIDKVLGVVNQIKPEIFTVVEQESNHNSPIFLDRFTESLHYYSTLFDSLEGVPSGQDKVMSEVYLGKQICNVVACDGPDRVERHETLSQWRNRFGSAGFAAAHIGSNAFKQASMLLALFNGGEGYRVEESDGCLMLGWHTRPLIATSAWKLSTN
What is the function of this protein?
Transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway.  Transcription coactivator of the zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling (PubMed:25035403).  No effect of the BOI proteins on its stability.  Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes.  Positively regulates XERICO expression.  In contrast to RGA, it is less sensitive to GA.  Its activity is probably regulated by other phytohormones such as auxin and ethylene.  Involved in the regulation of seed dormancy and germination, including glucose-induced delay of seed germination (PubMed:24989044).  Involved in the process leading to microtubules (MTs) dissociation in response to gibberellic acid (GA) probably by mediating the translocation of the prefoldin co-chaperone complex from the cytoplasm to the nucleus (PubMed:23583555).
What are the official names of this protein?
DELLA protein GAI, GRAS family protein 3, AtGRAS-3, Gibberellic acid-insensitive mutant protein, Restoration of growth on ammonia protein 2.
What is the protein family that this protein belongs to?
Belongs to the GRAS family. DELLA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2302_STRP2
Sequence: MSISFRTNTSMMNIAYKNRDLSDEEFKEEAHQFRDKEIKILEEKLKELNISCKVVGINSIKDMNEYKEIMENVNQAKEELKRIDELIAVRSSRIDFLEDKTLRITGNQR
What are the official names of this protein?
Uncharacterized protein SPD_2302.
Protein: PS11A_CAEEL
Sequence: MRETSSREDTNNIGKAPEMSGGTIMDTMTSLPHQNDQNVIRHLTNLVKSPASGDDDIKKKEDSIMELGNILAQNKQTEELRNMIEQTRPFLVSLGKAKAAKLVRDLVDLCLKIDDQDGDIKVGLVKECIQWATEQNRTFLRQTLTARLVRLYNDLQRYTQALPLAADLIRELKKVDDKDVLVEVELEESKAYYNLSNIGRARASLTGARTTANAIYVNPRMQAALDLQSGILHAADEKDFKTAFSYFYEAFEGYDSVDEKVSALTALKYMLLCKVMLDLPDEVNSLLSAKLALKYNGSDLDAMKAIAAAAQKRSLKDFQVAFGSFPQELQMDPVVRKHFHSLSERMLEKDLCRIIEPYSFVQIEHVAQQIGIDRSKVEKKLSQMILDQKLSGSLDQGEGMLIVFEIAVPDEAYQTALDTIHAMGEVVDALYSNASKIN
What is the function of this protein?
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  In the complex, rpn-6. 1 is required for proteasome assembly.  Plays a key role in increased proteasome activity in response to proteotoxic stress: induced by daf-16, promoting enhanced assembly of the 26S proteasome and higher proteasome activity, leading to extended lifespan.
What are the official names of this protein?
Probable 26S proteasome regulatory subunit rpn-6.1.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S9 family.
Protein: HSLO_THET2
Sequence: MGRILRGLAGGGDLRVVAAETTDIVEEARRRHGLSPTATAALGRAMTGALLLAQLLLKTPKERITLRVEGTGPLGGLVVEADAFGHVRGYVKNPRAEVPLREDGKLNVGELVGAGALRVDRSLPSGEVYTSTVPLVSGEIAEDLAHYLWQSEQIPSAVLLGVRVKGEGEVEVAGGVAVQVMPGAKEEVLGRLEANLKDLPGLTPLLRERGLEGALEALLAGLGFERTDLRALGYFQNEIPARFRCRCNREKALEALVFFTPEEREEMIVKEGGAEVVCHWCGEVYRFSPEEVRSLVAEVRCPDCGALWLYPKGDGTLARIEGETCRCGRKVELPSETRPQA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SQLE_PHATC
Sequence: MLVDRVENNEKQQQQMASSSDAMSDSSLSDDEIIEHVVHGKEPKSTYELSWVSNAIAWSGALVWPLMLTVPLLLSSMYSPISYRQVFPESWYVYDTLSNCAPKPLGLVLGILAVAVGQVFVWIFFYLFKFGYLGTDPRSIQSKGAREYIFREGLLTHIGQPEGFVLLIGYLAITWMLKLMPQSYYSFEGTIQYKELFMCLVLQDGIQYTMHVLEHIVSPAFYQMSHKPHHRFTNPRLFDAFNGSLMDTFCMIIIPLFVTANLVRHCNVWTYMAFGSSYACWLTLIHSEYVFPWDGIFRKLGLGTPADHHVHHKFFKFNYGHLFMWFDQLGGTYRDPSGFAPRVFRENV
What is the function of this protein?
Catalyzes the stereospecific epoxidation of squalene at the terminal double bond to form (S)-2,3-epoxysqualene, the first oxygenation step in sterol biosynthesis.
What are the official names of this protein?
Alternative squalene epoxidase, AltSQE, Alternative squalene monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Detected in the outer envelope of chloroplasts, which is termed the chloroplast endoplasmic reticulum and is continuous with the nuclear envelope.
Protein: GSA_AROAE
Sequence: MTSRNETLFQRAQKSIPGGVNSPVRAFRSVGGTPRFISRAEGARVWDADGKAYVDYVGSWGPAIAGHAHPAIVEAVREAALAGLSFGAPSEAEVDIAELICELMPSIEMVRLVSSGTEATMSAIRLARGFTGRDAIVKFEGCYHGHADSLLVKAGSGLLTFGNPSSGGVPADFAKHTIVLDYNDLQQVEDAFRARGGEIAAVIVEAIAGNMNLVKPLPGFLEGLRRLCTEYGVVLIFDEVMTGFRVGPQGVQGLYGIMPDLTTLGKVIGGGMPVGAFGGRRDIMEKIAPLGSVYQAGTLSGSPVAVAAGLASLKLLREPGFYENLGARTTQLVTGLAAAANDAGVTFSADSVGGMFGVYFSAAVPKSFADVMASDRDAFNRFFHAMLDAGHYFAPSAFEAGFVSAAHTAADIDETIAAAREVFARLG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.