PharMolix/UniProtQA huggingface dataset:
Protein: PRMA_METFK
Sequence: MAWISLRIDARDDNAELLSDTLMELGALSASIEDANAETPDEQPIFGEPGDPPPGIWQQNVVTALLDESADLDSLLEELSAATGITDFRYSTETIAEQDWVRATQSQFEPIRIRDDLWIVPSWHDAPNPDGLNIVLDPGLAFGTGSHPTTHLCLSWLADTVKPDTSVLDYGCGSGILAIAARKLGAGKVVGVDIDAQAIQSSVYNADQNQVDASFYLASDLPGGQFDIVVANILSSALSVLAPALARAARSGGRIALSGILREQADQVSAIYQEWFEMDAPVFMDSWVLLTGSRR
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPHA_NOSS1
Sequence: MRILKIQTLRGPNYWSIRRHKLIVMRLDLETLAETPSNEIPGFYEGLVEALPSLEGHYCSPGCHGGFLMRVREGTMMGHIVEHVALELQELAGMHVGFGRTRETATPGIYQVVIEYLNEEAGRYAGRAAVRLCQSIVDRGRYPKAELEQDIQDLKDLWRDASLGPSTEAIVKEAEKRGIPWMQLSARFLIQLGYGVNHKRMQATMTDKTGILGVELACDKEATKRILAASGVPVPRGTVINFLDDLEEAIEYVGGYPIVIKPLDGNHGRGITIDIRSWEEAEAAYEAARQVSRSIIVERYYVGRDHRVLVVDGKVVAVAERVPAHVIGNGRSTVAELIEEINQDPNRGDGHDKVLTKIELDRTSYQLLERAGYTLNSVPPKGTICYLRATANLSTGGTAVDRTDEIHPENVWLAQRVVKIIGLDIAGLDIVTTDISRPLRELDGVIVEVNAAPGFRMHVAPSQGIPRNVAGAVMDMLFPNEQSGRIPILSVTGTNGKTTTTRLLAHIYKQTGKVVGYTTTDGTYIGDYLVESGDNTGPQSAHVILQDPTVEVAVLETARGGILRSGLGFESANVGVVLNVAADHLGIGDIDTIDQLANLKSVVAESVYPDGYAVLNADDRRVAAMAEKTKANIAYFTMNSESELVRKHIQKGGVAAVYENGYLSIVKGDWTHRIERAEQIPLTMGGRAPFMIANALAASLAAFVQNVSIEQIRAGLRTFRASVSQTPGRMNLFNLGNYHALVDYAHNPASYEAVGAFVRNWTSGQRIGVVGGPGDRRDEDFVTLGKLAAEIFDYIIVKEDDDTRGRPRGSASELITKGITQVKPDARYESILDETQAINKGLDMAPANGLVVILPESVSRAIKLIKLRGLVKEEIQQQNSSTTVIDNQNGVASSSVINTLL
What is the function of this protein?
Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
What are the official names of this protein?
Cyanophycin synthetase, Cyanophycin synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MurCDEF family.
Protein: TRAY2_ECOLX
Sequence: MRRRNARGGISRTVSVYLDEDTNNRLIRAKDRSGRSKTIEVQIRLRDHLKRFPDFYNEEIFREVIEENESTFKEL
What is the function of this protein?
Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell.  It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations.  Part of the relaxosome, which facilitates a site- and strand-specific cut in the origin of transfer by TraI, at the nic site.  Relaxosome formation requires binding of IHF and TraY to the oriT region, which then facilitates binding of TraI.  Also positively regulates tra gene expression (By similarity).
What are the official names of this protein?
Relaxosome protein TraY.
What is the protein family that this protein belongs to?
Belongs to the TraY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_PSECP
Sequence: MSRAVGIDLGTTNSVVSVLEGGEPTVIANAEGGRTTPSVVAFSKSGEVLVGEIAKRQAVNNIDRTIASVKRHMGTDWKVDIDGKKYTAQEISARTLMKLKNDAESYLGEKVTDAVITVPAYFNDAERQATKEAGEIAGLNVLRIVNEPTAAALAYGLDKGKEDELILVFDLGGGTFDVSLLEVGKDEDNFSTIQVRATAGDNRLGGDDWDQRVVDYLLNQLKVKGIDLSKDKIALQRLREAAEQAKKELSSSSSTNVSLQYLSVTPDGPVHLDEQLTRAKFQDLTKDLLERTKKPFHDVIKEAGIKLSDINHIVLVGGSTRMPAVSELVKELAGGKEPNKGVNPDEVVAVGAALQAGVLKGERKDVLLIDVTPLSLGIETKGGVMTHLIERNTAIPTKRSETFTTADDNQPSVAIQVFQGEREFTRDNKPLGTFELTGIAPAPRGVPQVEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGTALSKEDIDRMVKDAEEHAAEDKARREATDTRNSAEQLAYSVDKLIADNADKLPEEVKTEVQADVDALKKALEGTDDAEVKTAFEKLQASQTKLGEAIYSQAGSPDGATGAAGAEGAAAGDGSKADEDIVDAEIIDEDEAKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MS116_YEAST
Sequence: MLTSILIKGRTPVLASRNLLAALSNCNHITWAVSRRLYNDGNRDQRNFGRNQRNNNSNRYRNSRFNSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSYRSCIKEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPIGKAMFEIRDYSSRDGNNKSYDYDDDSEISFRGNKNYNNRSQNRDYDDEPFRRSNNNRRSFSRSNDKNNYSSRNSNIY
What is the function of this protein?
ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns.  Specifically involved in the ATP-dependent splicing of the bl1 intron of COB.  Also required for efficient mitochondrial translation.
What are the official names of this protein?
ATP-dependent RNA helicase MSS116, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
Protein: ACPM_MYCTU
Sequence: MPVTQEEIIAGIAEIIEEVTGIEPSEITPEKSFVDDLDIDSLSMVEIAVQTEDKYGVKIPDEDLAGLRTVGDVVAYIQKLEEENPEAAQALRAKIESENPDAVANVQARLEAESK
What is the function of this protein?
Acyl carrier protein involved in meromycolate extension.
What are the official names of this protein?
Meromycolate extension acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_SALTY
Sequence: MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEAPVDFATLFGREAPVTLEIGFGMGASLVAMAKARPEQNFLGIEVHSPGVGACLASANEEGVENLRVMCHDAVEVLHKMIPDNSLSMVQLFFPDPWHKARHNKRRIVQVPFAELVLSKLKLGGVFHMATDWEAYAEHMLEVMSSIDGYKNLSESNDYVPRPESRPVTKFEQRGHRLGHGVWDLMFERVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MTGA_BACFN
Sequence: MKLRKPFRILRNLILFFFISSIGAVIFYRFVPVYVTPLMIIRSVQQLVSGEKVVCKHTWVPFDKISPSLPMAVIASEDNRFASHNGFDMIEIKKAMKENETRKKKRGASTISQQTAKNVFLWPQSSWIRKGFEVYFTFLIETCWSKERIMEVYLNSIEMGKGIYGAQATAKYKFKTTAAKLTRGQCALIAATLPNPIRFDSAHPSPYIKRRQGQILRLMNLVPKFPPVDKEKAKGQDTKKQKNKKKKK
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RNH2_YERPS
Sequence: MSETFIYPQANLIAGVDEVGRGPLVGAVVTAAVILDPNRPIVGLADSKKLSEKRRLSLYDEITEKALSWSLGRAEPEEIDQLNILHATMLAMQRAVSGLHIVPDYVLIDGNRCPKLQMPSLAVVKGDSRVAEISAASILAKVTRDREMTELDLLFPEYGFAQHKGYPTAFHLEKLAALGATVHHRRSFGPVKRVLGLV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_DECAR
Sequence: MDALMNFGTGIFGGAWPAVWTLIKIVLIVAPMMLGVAYLTYFERKVIGYMQVRIGPNRVGPWGLIQPIADGLKLLMKEIIVPSGANKGIFIIAPMLAIAPALAAWAVVPFTDSLVLANIDASLLYIMAITSMGVYGIILSGWASNSKYAFLGAMRSAAQMVSYEISMGFSLICVLMVSNSLNLVEIVNVQNQGRFAGWGLSFLSWNWLPLFPMFLVYLISGVAETNRAPFDVAEGESEIVAGFHVEYSGMAFAVFFLAEYANMILVSALTSIMFLGGWLSPVSFLPDGILWLFAKMSAILFLFLWFRATFPRYRYDQLMRLGWKVFVPICLIWLVVVGVWMMSPLNIWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS8_STAAM
Sequence: MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RS5_METHJ
Sequence: MAFDKSEWVPLTGLGRMVQAGEIKSIDEILSSGKPIKEPEIVDAFLPDLVDEVLDINMVQRMTDSGRRVKFRAVVVVGNRDGYIGFGQGKDAQVGDAIKKAIVSAKINLVKVRRGCGSWECGCSNPHSIPMLVTGDAGSVRVTLRPAPQGIGLVTGDIGKKVLELAGIRDVWAQTQGQTRTTINYAKATFNALKATNMIRLGGME
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: UP13_PSEMZ
Sequence: KLQELRMWSMLKKWILMFILDFPTR
What are the official names of this protein?
Unknown protein 13.
Protein: C75A1_PETHY
Sequence: MMLLTELGAATSIFLIAHIIISTLISKTTGRHLPPGPRGWPVIGALPLLGAMPHVSLAKMAKKYGAIMYLKVGTCGMAVASTPDAAKAFLKTLDINFSNRPPNAGATHLAYNAQDMVFAHYGPRWKLLRKLSNLHMLGGKALENWANVRANELGHMLKSMSDMSREGQRVVVAEMLTFAMANMIGQVMLSKRVFVDKGVEVNEFKDMVVELMTIAGYFNIGDFIPCLAWMDLQGIEKRMKRLHKKFDALLTKMFDEHKATTYERKGKPDFLDVVMENGDNSEGERLSTTNIKALLLNLFTAGTDTSSSAIEWALAEMMKNPAILKKAQAEMDQVIGRNRRLLESDIPNLPYLRAICKETFRKHPSTPLNLPRISNEPCIVDGYYIPKNTRLSVNIWAIGRDPQVWENPLEFNPERFLSGRNSKIDPRGNDFELIPFGAGRRICAGTRMGIVMVEYILGTLVHSFDWKLPSEVIELNMEEAFGLALQKAVPLEAMVTPRLQLDVYVP
What is the function of this protein?
Catalyzes the 3'5'-hydroxylation of naringenin and eriodictyol to form 5,7,3,'4',5'-pentahydroxyflavanone and 3',5'-hydroxylation of dihydrokaempferol and dihydroquercetin to form dihydromyricetin.
What are the official names of this protein?
Flavonoid 3',5'-hydroxylase 1, F3'5'H, CYPLXXVA1, Cytochrome P450 75A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: LEPA_STRA5
Sequence: MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MVP_CMVTR
Sequence: MAFQGTSRTLTQQSSAASSDDLQKILFSPDAIKKMATECDLGRHHWMRADNAISVRPLVPQVTSNNLLSFFKSGYDAGELRSKGYMSVPQVLCAVTRTVSTDAEGSLKIYLADLGDKELSPIDGQCVTLHNHELPALISFQPTYDCPMELVGNRHRCFAVVVERHGYIGYGGTTASVCSNWQAQFSSKNNNYTHAAAGKTLVLPYNRLAEHSKPSAVARLLKSQLNNVSSSRYLLPNVALNQNASGHESEILNESPPFAIGSPSASRNNSFRSQVVNGL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: DEF69_ARATH
Sequence: MGSSKLLVAFTLIVMMTISYDLFTGIGIDARTVPPTCYESCNATFQNPECNKMCVGLAYKDGSCIYPPPEVDGLPPKRPYFPRCCCNPIILSPPSP
What are the official names of this protein?
Defensin-like protein 69.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2199_YERPE
Sequence: MPITANTLYRDSFNFLRNQIAAILLLALLTAFITVMLNQTFMPASEQLSILSIPENDITSSGNLSISEIVSQMTPEQQMVLLRVSAVATFSALVGNVLLVGGLLTLIAMVSQGRRVSALQAIGLSLPILPRLLVLMFISTLVIQLGLTFFIVPGVAIAIALSLSPIIVTNERMGIFAAMKASAQLAFANVRLIVPAMMLWIAVKLLLLFLISRFTVLPPTIATIVLSTLSNLASALLLVYLFRLYMLLRPVSLDKQ
What are the official names of this protein?
UPF0259 membrane protein YPO2199/y2042/YP_1997.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ERG3A_SCHPO
Sequence: MDYLLNYADQYALDSIYNAVYPLARDNIVRQSISLFFLTWFGGMFLYLTFASLSYQFVFDKSLMDHPKFLKNQVFMEVLTALQNLPGMALLTVPWFLAELHGYSYLYDNISDYGLKYFLCSLPLFVMFSDFGIYWAHRFLHHRYVYPRLHKLHHKWIICTPYASHAFKSADGFLQSLPYHLFPFFFPLHKLTYLALFTFVNFWSIMIHDGKYISNNPIINGAAHHNGHHIYFNYNYGQFTTLFDRLGNSFRAPDEAWFDKDLRQNEDVLRVELMEYEAIRNEVEGDDDREYIANSAKKNH
What is the function of this protein?
C-5 sterol desaturase; part of the third module of ergosterol biosynthesis pathway that includes by the late steps of the pathway (PubMed:18310029).  Erg31 and erg32 catalyze the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol (By similarity).  The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane.  Firstly, the squalene synthase erg9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids.  Secondly, squalene is converted into lanosterol by the consecutive action of the squalene epoxidase erg1 and the lanosterol synthase erg7.  The lanosterol 14-alpha-demethylase erg11/cyp1 catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.  In the next steps, a complex process involving various demethylation, reduction and desaturation reactions catalyzed by the C-14 reductase erg24 and the C-4 demethylation complex erg25-erg26-erg27 leads to the production of zymosterol.  Erg28 likely functions in the C-4 demethylation complex reaction by tethering erg26 and Erg27 to the endoplasmic reticulum or to facilitate interaction between these proteins.  Then, the sterol 24-C-methyltransferase erg6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.  The C-8 sterol isomerase erg2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol.  The sterol-C5-desaturases erg31 and erg32 then catalyze the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol.  The C-22 sterol desaturase erg5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain.  Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase erg4 to produce ergosterol (PubMed:18310029) (Probable).  In the genus Schizosaccharomyces, a second route exists between lanosterol and fecosterol, via the methylation of lanosterol to eburicol by erg6, followed by C14-demethylation by erg11/cyp1 and C4-demethylation by the demethylation complex erg25-erg26-erg27 (PubMed:8586261) (Probable).
What are the official names of this protein?
Delta(7)-sterol 5(6)-desaturase erg31, C-5 sterol desaturase erg31, Ergosterol Delta(5,6) desaturase erg31, Ergosterol biosynthetic protein 31, Sterol-C5-desaturase erg31.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RF3_ACAM1
Sequence: MPTELQTELAEAVEARRNFAIISHPDAGKTTLTEKLLLYGGAIHEAGAVKARRAQRHATSDWMEMEQQRGISITSTVLQFAYQHCQINLLDTPGHQDFSEDTYRTLAAADNAVMLVDAAKGLEPQTRKLFEVCKLRSLPIFTFINKLDRPGREPLELLDEIEQELGLQTYAVNWPIGMGDRFQGVFDRRSRKIHLFQRSDHGKREAIDTQIDLGDPQIESLLDQELYFQLKDELELIEELGSPLDLEQVHNGQMTPIFFGSAMTNFGVELFLEAFLDYALKPGAYESTQGTIEPTYEDFSGFVFKLQANMDPKHRDRVAFIRVCSGKFEKDMTVSHARTGKTIRLSRPQKLFAQGRNSLEEAYPGDIIGLNNPGVFAIGDTIFKGKKLAYEGIPCFSPELFAYLKNPNPSKFKQFQKGVSELREEGAVQIMYSEDEIKRDPILAAVGQLQFEVVQFRLQNEYGVETRLELLPYSVARWVKGGWSALESVGRIFNAITVKDSWGRPVLLFKNEWNLHQVHGDHPDLELSAIAPLAVDQNMVS
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF140_ARATH
Sequence: MSKSLQLIVTVLCIFTILVLGEICLAKGQPLEEMVECKEVLWPEECKYDACAFACALKRHGKGGCLEGPDYRSACICQYACKRS
What are the official names of this protein?
Defensin-like protein 140, Low-molecular-weight cysteine-rich protein 15, Protein LCR15.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: CDN1C_HUMAN
Sequence: MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTPRKRLR
What is the function of this protein?
Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2.  Negative regulator of cell proliferation.  May play a role in maintenance of the non-proliferative state throughout life.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2.
What is the protein family that this protein belongs to?
Belongs to the CDI family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FUT7_MOUSE
Sequence: MPTPCPPACLSTPGTHRLLPFPDWKAPSWESRKEATCNSSSPGPWAEPTVQGYHPTRRLRAWGGLAGGATFMVIWFFWLWGSAPGSAPVPQSTLTILIWHWPFTNRPPELPGDTCTRYGMASCRLSANRSLLASADAVVFHHRELQTRQSLLPLDQRPHGQPWVWASMESPSNTHGLHRFRGIFNWVLSYRRDSDIFVPYGRLEPLSGPTSPLPAKSRMAAWVISNFQERQQRAKLYRQLAPHLQVDVFGRASGRPLCANCLLPTLARYRFYLAFENSQHRDYITEKFWRNALAAGAVPVALGPPRATYEAFVPPDAFVHVDDFSSARELAVFLVSMNESRYRGFFAWRDRLRVRLLGDWRERFCTICARYPYLPRSQVYEDLESWFQA
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein or a glycolipid-linked sialopolylactosamines chain through an alpha-1,3 glycosidic linkage and participates in the final fucosylation step in the biosynthesis of the sialyl Lewis X (sLe(x)), a carbohydrate involved in cell and matrix adhesion during leukocyte trafficking and fertilization (PubMed:8752218, PubMed:8626519, PubMed:15843584, PubMed:10882744, PubMed:11535629, PubMed:12359718, PubMed:11485743).  In vitro, also synthesizes sialyl-dimeric-Lex structures, from VIM-2 structures and both di-fucosylated and trifucosylated structures from mono-fucosylated precursors (By similarity).  However does not catalyze alpha 1-3 fucosylation when an internal alpha 1-3 fucosylation is present in polylactosamine chain and the fucosylation rate of the internal GlcNAc residues is reduced once fucose has been added to the distal GlcNAc (By similarity).  Also catalyzes the transfer of a fucose from GDP-beta-fucose to the 6-sulfated a(2,3)sialylated substrate to produce 6-sulfo sLex mediating significant L-selectin-dependent cell adhesion (PubMed:8752218, PubMed:10894166).  Through sialyl-Lewis(x) biosynthesis, can control SELE- and SELP-mediated cell adhesion with leukocytes and allows leukocytes tethering and rolling along the endothelial tissue thereby enabling the leukocytes to accumulate at a site of inflammation (PubMed:15843584, PubMed:8752218, PubMed:10882744, PubMed:11535629).  May enhance embryo implantation through sialyl Lewis X (sLeX)-mediated adhesion of embryo cells to endometrium (By similarity).  May affect insulin signaling by up-regulating the phosphorylation and expression of some signaling molecules involved in the insulin-signaling pathway through SLe(x) which is present on the glycans of the INSRR alpha subunit (By similarity).
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase 7, Fucosyltransferase 7, Fucosyltransferase VII, Fuc-TVII, FucT-VII, Galactoside 3-L-fucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single- pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: MURI_HAEDU
Sequence: MKPTILLYDSGMGGLTVYDEIRKKLPNAHYLYYFDNACFPYSEKPTEVLVERATKMVQKMAKNYPLDLVVVACNTASTVVLPTLRKIFPFPIVGTVPAIKPAAALSQTKTIGLLATKGTITRPYVLSLIEQYAPNCQIEKIGSTALVELVEQKLQTGVIDLTRLTPIIADWQNHPTLDTVILGCTHFPMAKTELQQLLPNVKYFLDSGNAIANRVTHLIMHSPHNQQLEKQRENLAFCTQQNNQFKQQAKIMQRWGFPQLNTLMI
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.