PharMolix/UniProtQA huggingface dataset:
Protein: BPT_PSEPF
Sequence: MTELARLKFYATQPHSCSYLPEEQATTLFLDPSQPMDVHVYADLSEMGFRRSGDHLYRPHCQNCNACVPARIPVAQFNPNRQQKRIFKRNVDLQVRPVKPAFSEEYFDLYQRYIEQRHADGDMYPPSRDQFSTFLVRDLPFSRFYEFRLDGRLLAVAVTDLLPNGLSAVYTFYEPQEERRSLGRYAILWQIAEAQRLGLEAVYLGYWIKNCKKMNYKTQYRPIELLINQRWVVLN
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAOX_POPTR
Sequence: MESTLKEMRDGASVLDMDPKSTVGGGVEDVYGEDRATEDQLVTPWTISVASGYTLLRDPHHNKGLAFTEKERDAHYLRGLLPPTTISQQLQEKKLMNTIRQYQLPLQKYTAMMELEERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFKRPQGLYISLKEKGKVLDVLKNWPQKSIQVIVVTDGERILGLGDLGCQGIGIPVGKLSLYTALGGVRPSACLPVTIDVGTNNEQLLKDEFYIGLRQRRATGQEYSELLHEFMTAVKQNYGEKVLIQFEDFANHNAFDLLAKYGTTHLVFNDDIQGTAAVVLAGLISALKLLGGSLADHTFLFLGAGEAGTGIAELIALEMSRRSKTPLEETRKKIWLTDSKGLIVSSRKESLQHFKKPWAHEHEPVKGLLEVVKAIKPIVLIGTSGVGKTFTKEVIEAMASFNEKPLILALSNPTSQSECTAQEAYTWTKGKAIFASGSPFDPVEYEGKVFVPGQSNNAYIFPGLGLGLVISGAIRVHDDMLLAAAEALAGQIKEEYLAKGLIYPPLSNIRKISVQIAANVAAKAYELGLATRLPRPENLVKHAESCMYSPAYRYYR
What are the official names of this protein?
NADP-dependent malic enzyme, NADP-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2RX4_BOVIN
Sequence: MTGCCTVLGAFLFEYDTPRIVLIRSRKVGLMNRTVQLLILAYVIGWVFVWEKGYQETDSVVSSVTVKAKGVTMTNTSKLGFRIWDVADYVIPAQEENSVFIMTNMVITMNQTQGLCPEIPGKTTVCETDANCTAGSAGTHSSGVATGRCVSFNGTLKTCEVAAWCPVEDDTEVPKPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTAYLKTCIYDAKTDPFCPIFRLGKIVESAGHSFQDIAIEGGIMGIQIKWNCNLDRAASFCLPRYSFRRLDTRDLAHNVSPGYNFRFAKYYSDLKGAEHRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGVATVLCDVIVLYCMKKRYYYREKKYKYVEDYEQGLGNQMEQ
What is the function of this protein?
Receptor for ATP that acts as a ligand-gated ion channel.  This receptor is insensitive to the antagonists PPADS and suramin (By similarity).
What are the official names of this protein?
P2X purinoceptor 4, P2X4, ATP receptor, Purinergic receptor.
What is the protein family that this protein belongs to?
Belongs to the P2X receptor family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: YE8A_METJA
Sequence: MLIAIGIMFQPLQYPTIPCIIFMVIVGLGLLFAFQFILGYGFEMHRQITIKDRIAFRNYVVGKIFNVLVEHSYYGLLLSTFNLFVYKKAITIRLCFIFAISIVIFWILGGKLIKKSLKLCFSWFYFFINPSISHKCNSK
What are the official names of this protein?
Uncharacterized protein MJ1489.1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTH_ECO81
Sequence: MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWIPVEGERSIPLAKRRVGSPLLWSPNEEEDRQLREDWEELMDMIVLGQIERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFTSALLARHFLIQ
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KANK_STRKN
Sequence: MSSQLALRGPELSANLCKPEEDTLRVLVTGGSGNVGVGVVRALNAARHHVVVASRGYSPALLPEGVRAVRLERTEPDAYTRLVAAEKPDAVIDLTCHDAADAAVTLRACAGVDRVVVVSSVTAAGPATTTPVTEATAAPPLSEYGIDKLAVEETVRAAWADGTSQALLVRLGAVYRLGADLDGQLAEDGCWLAHAAAGAPAVLADDGAARWNLLHADDAGAALAELLANDRARGVLVHLASRHPLPWRELYERVHHALGRPFNPVSVPAEWAAEQLEDAEFLAETSRWDQVFDLGLLDRLAPSYQERGGPSRVTEVALWLIRQGRVGDAELGAEIQELPARLAAVRTAPGLV
What is the function of this protein?
Mediates the conversion of 2'-dehydrokanamycin A into kanamycin A.
What are the official names of this protein?
2'-dehydrokanamycin reductase, Kanamycin biosynthesis protein K.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: FXP1B_DANRE
Sequence: MMQESGTEAANGTAHQNGAPPSVEGHREVRSKSTTPSSDITASDIINFQQHQALQVARQILLQQQQQSSVHKSPKNNDKQPATQVPVSVAMMTPQVITPQQMQQILQHQVLSPQQLQLLLQQQQALMLQQQLQEFYKKQQEQLHLQLIQQQHGSKQQSKEVSAQQLAFQQQLLQVQQLQQQHLLSLQRQGLLSIQPNQTLPLHTLTQGMIPAELQQLWKEVTNSHVKEENSVTNNGHRGLDLSSPSPVPLKNHNQHGSTNGQYISHSLKREGSTLDDHSPHSHPLYGHGVCKWPGCEAVFEDFQSFLKHLNNEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKPTPQPLNLVSNVALSKTAPAASPPLSLPQTPTTPTAPLTPLSQTHSVITPTSLHSVGPIRRRYSDKYNMPISPDIVQNKEFYMNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDELEFQKRRPQKISGSPALVKNIHTTLGYGPALSAAFQASMAENIPLYTTASIGSPTLNSLASVIREEMNGAMDHGNSNGSDSSPGRSPLPAMHHISVKEEPMDPEEHEGPLSLVTTANHSPDFDHHRDYEDDHGTEDML
What is the function of this protein?
Transcriptional repressor.
What are the official names of this protein?
Forkhead box protein P1-B.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACPS_MICLC
Sequence: MIVGVGVDVVDVPRFRAQLERTPALRARLFTEDERDLPLRSLAARFAAKEAIAKAMGAPPGMMWHHCWIPRPDHGDGRPTVHLTGTVQAQAEALGITHWHLSLSHDGDVATAYVVAERRAAEEESA
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAR3_ARATH
Sequence: MNNSTRLISLFSPHPPPLFLLRGLYISRIANLRRFHRRAFPPSSVASTNLCSFRPLVSLPPLIPTFPIGRFYNHQVRVSAADFVPSYHNQQLPEWTELLQSLSKAGYFSDSGSISGLESEFFPGFPDELLRPALACLALARERPELLEMLSRRDVEVLVENGKPFLFKTGPDSLKRMSLYLRSGLQGIGKLMDMEKASTVDLMRLILSYVVDVASSEESKQHNKEIMESSVRSLLSQIAKMSLRPPESNVHDTMQNQYSDRDGQGVRSFQNNVEMKRGDWICSRCSGMNFARNVKCFQCDEARPKRQLTGSEWECPQCDFYNYGRNVACLRCDCKRPRDSSLNSANSDYSSDPELERRLVENEKKAQRWLSKVAQGGSDANSVDTDEDFPEIMPLRKGVNRYVVSTRKPPLERRLANTENRVATDGNSKRSDDNALGSKTTRSLNEILGSSSSLTSRSDDKNVSSRRFESSQGINTDFVPFVPLPSDMFAKKPKEETQIGLIDNIQVDGFSGGNQNVYQEDKSDANHSGKETDRLEKEDHKSEEPARWFKRVTELHNVSDLESAIPQEISPEKMPMRKGENRFVVSRKKDRSLTSPAYKRPEDSDFVPFVPFPPDYFAKEKQPKESIDTLPAPATENVSQVVQQEPREPSINKSDTVAVKIRNGKSLEGSLVKESDLLDMSEEAKAERWFKRVAEIKNISELSEIPDEDFPSIMPMRKGVNRFVVSKRKTPLERRLTSQRHQRNPHITNSDPTGKGDK
What is the function of this protein?
Probable component of some protein complex required for chloroplast and palisade cell development (PubMed:15340011).  Involved in C-to-U editing of chloroplastic RNA.  Controls a large number of chloroplastic editing sites.  Binds the editing recognition trans-factors PCMP-H51/CRR28 and PCMP-H12/OTP82 (PubMed:25768119).
What are the official names of this protein?
Zinc finger protein VAR3, chloroplastic, Organelle Zinc finger 1, Protein VARIEGATED 3.
What are the subcellular locations of this protein?
Plastid, chloroplast. Note=Localizes at punctuate loci in chloroplasts.
Protein: REX_PORG3
Sequence: MKTIANESSLLDTKVPEPTLRRLPWYLSYVQLLHADGCESVSSTRIARAVGVDASLVAKDLSYVSVDGRTRVGYRVADMVAVLNDFLGFTHHHRAFLFGVGSLGAALLQDSGLRHFGLEIAAGFDVNPDIVDTNINGIPVYHKSRVAELCARERVDIGILTVPIRAAQSMADEMIAAGIKAIWNFTPWRISVPEGVVVQNTSMYAQLAVMFNRMKSLP
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_OENPA
Sequence: MATIRADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIYGLDEVMAGELVEFEEGTIGIALNLESKNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEISSSESRLIESPAPGIISRRSVYEPLQTGLIAIDAMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGNNVICVYVAIGQKASSVAQVVNALQERGAMEYTIVVAEAADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDPSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSRLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFSSDLDKATQNQLARGQRLRELLKQSQAKPLTVAEQILTIYTGTNGYLDSFEIAQVRKFLDELRDYVKTRKPQFEEIISSTKIFTEEAQALLKDAIQEQKELFLVQE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: Y424_CLOBK
Sequence: MRIGFDHEKYLEEQSKYILERVNNYDKLYLEFGGKLLFDLHAKRVLPGFDENAKIKLLHKLKEKVEIIICLYAGDIERNKIRGDFGITYDVDVLRLIDDLRGYDLEVNSVVITRYSGQPATNIFINKLERRGIKVYRHEATKGYPTDVDTIVSDEGYGKNPYIETTKPIVVVTAPGPGSGKLATCLSQLYHEYKRGNVAGYSKFETFPVWNVPLKHPLNIAYESATVDLKDVNMIDSFHFDAYNKVAVNYNRDIESFPVLKRIIEKITGEESVYKSPTDMGVNRVGFGIVDDEVVKEASKQEIIRRAFKTACEYKKGYVDKETFHRAKLIMEEMNLKEEDRKVVIPAREYAAKLKERANKSETCTVVALELEDGTILTGRSSELMDGTAAVILNAVKHYANISDEIHLISPVILEPIINLKAKTLGSKRTALSCEEVLIALSICAATNPTAQVAMGKLPMLKGCQAHSTTILSTNEEQTFRKLGIDVTCDPEYISESLYYNN
What are the official names of this protein?
UPF0371 protein CLD_0424.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: HTPX_AGRFC
Sequence: MNMMRTAMLLAFMTALFMGVGFLIGGKGGMMIALLIAAGMNLFSYWNSDKMVLSAYRAREIDEANAPEFFHMIRDLSQNAGLPMPKVYIYDSPQPNAFATGRNPENAAVAASTGLLERLTPEEVAGVMAHELAHVQNRDTLTMTITATLAGAISMLGNFAFFFGGNRENNNNPLGFIGVLVAMIVAPLAAMLVQMAISRTREYSADRRGAEICGNPLWLASALQKISGMAQQIHNDDAERNPATAHMFIINPLSGERMDNLFSTHPNTENRVAALHAMAQEFSPRASTPPPSGDRPVRKSGSVPTTGWRRGNENERKGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLP1_ORYSI
Sequence: MAGCVVGEPASAPGQRVTLLAIDGGGIRGLIPGTILAFLEARLQELDGPDARLADYFDCIAGTSTGGLITAMLAAPGDHGRPLFAASDINRFYLDNGPRIFPQKRCGMAAAMAALTRPRYNGKYLQGKIRKMLGETRVRDTLTNVVIPTFDVRLLQPTIFSTYDAKSMPLKNALLSDICISTSAAPTYLPAHCFQTTDDATGKVREFDLIDGGVAANNPTMVAMTQITKKIMVKDKEELYPVKPSDCGKFLVLSLGTGSTSDQGMYTARQCSRWGIVRWLRNKGMAPIIDIFMAASSDLVDIHAAVMFQSLHSDGDYLRIQDNTLHGDAATVDAATRDNMRALVGIGERMLAQRVSRVNVETGRYVEVPGAGSNADALRGFARQLSEERRARLGRRNACGGGGEGEPSGVACKR
What is the function of this protein?
Possesses non-specific lipolytic acyl hydrolase (LAH) activity.  Hydrolyzes phospholipids as well as galactolipids.  May play a role in disease resistance (By similarity).
What are the official names of this protein?
Patatin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
Protein: GIP3_PHYIN
Sequence: MKIISAVAASSIALGAVSATTDHVSRMLVLGGAVVPSGTKTYTTGIRPTIDGDNFCGGSLISPTHVLTTTACLRGIKPPNWVSVGTHYLNGTHDGEQIKVVAAQNHTNFNSTSGSFDVALLTLEKPSRFKPVKLPAADDSDIVAGMWSKLVGWGYTGYPEKTKAYELQGVSLQVWDNEQCGQLYPVDDTMVCAGGVKGKDSCDGDTGGPLIKERGPGDEDDIVVGLVSWGSECGVGYPGVYSRVSKALEWINSITKGK
What is the function of this protein?
Secreted effector that suppresses host plant glucan elicitor-mediated defense responses (PubMed:18624645).  Targets host endoglucanases and inhibits the endoglucanase-mediated release of elicitor-active glucan oligosaccharides from P. infestans cell walls (PubMed:18624645).
What are the official names of this protein?
Glucanase inhibitor protein 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NTPP_SACEN
Sequence: MRFVLASASPARLSVLRSAGIDPLVRVSGVDEDAVAAGLTDPTPPELVTALAAAKAEAVLPAVAAEAPDAVVVGCDSMLSAPDGEIVGKPGTPQAAAERWRKAAGRSGELLTGHAVVVLRGGEVVARTQGHLATTVRFSEPTEAELDAYIATGEPLHVAGGFTLEGFGGWFIEGVDGDPSSVLGISLPLTRKLLAEVGVSVVTLWGPPVAR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSCL2_RAT
Sequence: MVNDPPVPALLWAQEVGHVLAGRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYYRTDCDSSTASLCSFPVANVSLTKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQMLDTLVFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEVHSKRVQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIALFSYMQWVWGAVWPRHRFSLQVNIRQRDNSGHGAQRRISRHQPGQASTQQSDVTEDGESPEDPSGTEGQLSEEEKPEKQPLNGEGEQEPEASDGSWEDAALLTEASTSALAPETLGSLRQRQTCSSS
What is the function of this protein?
Plays a crucial role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity).  In association with LDAF1, defines the sites of LD formation in the ER (By similarity).  Also required for growth and maturation of small nascent LDs into larger mature LDs (By similarity).  Mediates the formation and/or stabilization of endoplasmic reticulum-lipid droplets (ER-LD) contacts, facilitating protein and lipid delivery from the ER into growing LDs (By similarity).  Regulates the maturation of ZFYVE1-positive nascent LDs and the function of the RAB18-ZFYVE1 complex in mediating the formation of ER-LD contacts (By similarity).  Binds anionic phospholipids including phosphatidic acid (By similarity).  Plays an important role in the differentiation and development of adipocytes (By similarity).
What are the official names of this protein?
Seipin, Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the seipin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet. Note=Localizes at endoplasmic reticulum-lipid droplets (ER-LD) contact sites.
Protein: COAE_ANAMM
Sequence: MIVFGLSGGAGSGKSTVAAMFAQSCNAAVFDADKIVHSMYSGDAIITGLVAKYFPDCICNGVVSRERLSKHFFSYGPLWLEFQSILHSIVLRQQRKFILEQGKIGRDYAVLDVPLLLEAGFWRCCDFVINVDVHKSLQWHRLRQRGLSEREIEFLLSLQMPRGSRRNFADFYVNCGGRKGEVLKSVLQIVGSLNAGRHRFRVARKKLAMRSALDRRASTMASA
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAFA_CORDI
Sequence: MGEYERTVFTRRITGVETEYGITCVGDNSRRRLGADEAARYMFRPVVEEWGSSNVFIPNGARLYLDVGSHPEYASAECDSLSQLIAYDRAGDKIVDQLAQRAETALATEGIGGRVYLFKNNLDSLGNSYGCHENYLVSRDVVLKTLGRQLLPFLITRQLICGAGSIQDGQFQVSQRADHVWEGVSSATTRSRPIINTRDEPHADSHRFRRLHVIVGDSNMSETTCALKIGSTQLVLEMIEAGALSHDLELSNEIAAIREISRDITGMAPVPLKAGTSMPAIEIQRRYAEKALCWLEQRGDTEGTPNAEMHKVVSLWLDTISAIESNDLQALSRDIDWAIKLSLLRRAQRRIGCSESDFTHPKLAQLDLAYHDIRAGRGVFPVLESKQLVNRWINDTDIEQATRIAPSTTRAALRGEFLTAAKKLQAPISADWLRLKVNRPEPQIIELTDPFENTDDRVDQLISYMRNHAASYSTDTAIS
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: IPUA_ASPNG
Sequence: MRSTGYLLTLSAAFQVAQAAVTANNSQLLTWWHNTGEINTQTPVADGNVRQSGLYSVKVQTTPASSSLYYDSFVYLAIPGNGMSDQLQYTQGYNQTQAWTSFLYSHDATVKISRNGSSANSNVVIRPTSLNFPVRYDNQSVYITVPYSPTGYRFSVEFDDDLISLAPSGARQPENALLIFASPFENSSTKPQPGSPNSIAPAPGRVLGLNTTSASTVVFNPGVYYFTGHDHMVLSSSVTWVYFAPGAYVKGAVEFLSTASEVKASGHGVLSGEQYVWYADPDEGYQKASGANNNGLRMWRGTLGNSSQTFVLNGVTVSAPPFNSMDWSGNSLDLITCRVDDYKQVGAFYGQTDGLEMYPGTILQDVFYHTDDDGLKMYYSNVTARNIVMWKESVAPVVEFGWTPRNTENVLFDNVDVIHQAYANAGNNPGIFGAVNNYLYAPDGLSSNHSTGNSNMTVRNITWSNFRAEGSSSALFRINPIQNLDNISIKNVSIESFEPLSINTTESWMPVWYDLNNGKQITVTDFSIEGFTVGNTTITASNAASVGRIDGVDPAYAGSVHYID
What is the function of this protein?
Hydrolyzes pullulan, a linear polymer which is composed of maltotriose units with alpha-1,6 glucosidic linkages, to produce isopanose (Glca1-4Glca1-6Glc).
What are the official names of this protein?
Isopullulanase.
What are the subcellular locations of this protein?
Secreted.
Protein: COX1_ANOQU
Sequence: MSRQWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGAFIGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWMLPPSLTLLISSSMVENGAGTGWTVYPPLSSGIAHAGASVDLAIFSLHLAGISSILGAVNFITTVINMRAPGITLDRMPLFVWSVVITAVLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGEPNLYQHLFWFFGHPEVYILILPGFGMISHIITQESGKKETFGNLGMIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTGIKIFSWLATMHGTQLTYSPAMLWAFGFVFLFTVGGLTGVVLANSSIDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFIHWYPLLTGLTMNPNWLKLQFAMMFVGVNLTFFPQHFLGLAGMPRRYSDFPDSYLAWNIVSSLGSTISLFAILYFLFIIWESMITQRTPAFPMQLSSSIEWYHTLPPAEHTYAELPLLTNNF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YACL_BACSU
Sequence: MLKRIVQAFFIIFGGVVGIFLIPELFVLLNIQDIPLITNAYTSAAIGAIIFFLISIWGTEYVVNWVKWIEDSLLKAPVPDLLFGSLGLVFGLIIAYLIVNVIPLDNIPYRIFSTIIPVFLAFFLGYLGFQVGFKKKDELISLFSISARMQKKKGTADEEHEVQDKKLKILDTSVIIDGRIADICQTGFLEGVIVIPQFVLEELQHIADSSDVLKRNRGRRGLDILNRIQKELDIEVEIYEGDFEDIQEVDSKLVKLAKLTSGVVVTNDFNLNKVCELQKVAVLNINDLANAVKPVVLPGEEMNVQVIKDGKEHNQGVAYLDDGTMIVVEEGRNYIGKHIDVLVTSVLQTAAGRMIFAKPKLLEKAL
What is the function of this protein?
An RNase.
What are the official names of this protein?
Uncharacterized PIN and TRAM-domain containing protein YacL, Putative RNase YacL.
What is the protein family that this protein belongs to?
In the central section; belongs to the PINc/VapC protein family.
Protein: TILS_WIGBR
Sequence: MLKKFFKEISYKKSYVLAFSGGLDSTVLLHMISLYIKKIKNNNNFFKKIFKFRAVYINHNICKESKYWSNHCHDQCLKYKVFFKSINIFISDFSEGIESSARRERYKALFSDLNPEEVLITAHHQDDQIETILLSLKRGSGPRGISGMQSIKKFDSHIIKRPLLHCKKEDIKLYAIKHNLNWIDDKSNLNIKFDRNFLRSEIIPLLKKRWPNIGNTISRSAKLCFDQEKLLNELLKDTLNSLVEKDKSLKFIELFKMSEIKRFAILRKWFCLNNFKMPSLSQLKHIWKNVIISKKDSKAEIKINNNIIKRFKKNLYFIPIYSKNHLKNIIFKTSLNHSKKIVLPYDLGTLITKPIMINENFIKKINFFYYNNKKKFIFLINLNYMKKMSFTVKLWILFIC
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CYNBR
Sequence: MTNIRKSHPLFKLINDALIDLPAPSNISSWWNFGSLLGICLLIQILTGLFLAMHYTSDTTTAFQSVTHICRDVNYGWVLRYLHANGASMFFICLFLHVGRGLYYGSYIYTETWNVGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIISALVVVHLLFLHETGSNNPTGIPSDMDMIPFHPYYTIKDMLGALIMILALLLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALMPLLHTSKQRSMMFRPLSQCMFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFSLILVLMPLVSIVENRLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MTND2_NOCFA
Sequence: MTLLQVMAADDAARVRLRTTEEAAIAAELAAHGITFDRWPVLDDAAALSSDDLLAHYADRIAALNADGRYRHIDVARIHPDDADPQWPQTARAARTKFLDEHRHAEDEVRFFAAGRGCFYLHLGAEVLAVVCEGGDLMSVPAGTLHWFDMGERPDFIAVRFFEEADGWVGDFTGDRISAGFPTLDDLLTAP
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase 2, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2, DHK-MTPene dioxygenase 2, Acireductone dioxygenase (Fe(2+)-requiring) 2, ARD' 2, Fe-ARD 2, Acireductone dioxygenase (Ni(2+)-requiring) 2, ARD 2, Ni-ARD 2.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: WHIA_STRCO
Sequence: MTAAVKSEISQLPVTRTCCRKAEVSAVLRFAGGLHLVSGRIVIEAELDTGNAARRLKRDILEIFGHSSELIVMAPGGLRRGSRFVVRVVAGGDQLARQTGLVDGRGRPIRGLPPQVVSGATCDAEAAWRGAFLAHGSLTEPGRSSSLEVTCPGPEAALALVGAARRLSIPAKAREVRGVDRVVVRDGDAIGALLTRLGAHDSVLAWEERRLRREVRATANRLANFDDANLRRSARAAVAAGARVQRALEILADDVPEHLAAAGRLRMEHKQASLEELGALADPPLTKDAVAGRIRRLLAMADKRASDLGIAGTDANLGEEELADNLVG
What is the function of this protein?
Involved in cell division and chromosome segregation (By similarity).  Involved in sporulation (PubMed:16484182, PubMed:22355671).  May coordinate the cessation of aerial hyphae growth and subsequent chromosome segregation and/or septation (PubMed:16484182, PubMed:22355671).  Required for expression of the ParB partioning protein during sporogenesis.  Activates its own transcription and represses WhiB (PubMed:16484182).  Binds with low affinity to its own promoter and to the Parp2 sporulation-specific promoter.  Also binds directly to the RNA polymerase sigma factor WhiG, leading to inhibition of WhiG-dependent transcription in a dose-dependent manner (PubMed:22355671).
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.