PharMolix/UniProtQA huggingface dataset:
Protein: TAL_ALKOO
Sequence: MKLFIDTANIEEIREISKWGILSGVTTNPSLIAKEGRDLKAVIQEITELVDGPISAEVVGETYEEMLEEAKELVRIHPNVVIKVPMTEEGLKAVSKFSEQGIRTNVTLVFSAPQALIAARAGATFVSPFLGRLDDIGADGIGLIEDIAHIFHIHHIDTEIIGASIRHNLHVMNAAKAGAHIATIPYKVLKDMVKHPLTDIGIEKFMADWNKTKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_CLOAB
Sequence: MKYMGLNDIRESYLSFFEKKEHLRLPSFSLIPKNDKSLLLINAGMAPLKPYFTGLQTPPKTRVTTCQKCIRTGDIENIGKTSRHGTFFEMLGNFSFGDYFKEEVISWAWEYITEVLKFPKDRIYITIYLDDDEAFKIWTEKAGVDPSRIFRFGKEDNFWEHGSGPCGPCSEMHFDRREKPDLIKTREKFIELQDKDEVIEFWNLVFTQFDKDEDGNYNKLKNPNIDTGMGLERIATIMQNTDSIFEIDTIREVLDAVCKICNVKYGENHKNDVSLRIITDHIRSVTFMISDGILPSNEGRGYVLRRLLRRAARHGKTLGIEKTFLCGLCDVVIKNSKGAYKELEEKQDYIKNVIEIEEKRFDETLDSGMEILKNYIDELSLENKKVMSGEKAFRLYDTYGFPVELTQEILEEKGIEIDMNDFHSEMEKQKNRARDAREESNYMGKEIKLIDKLPESVTTKFVGYNSTSTDSKVEVLIKDDEFVSTINEGESGIVVTEETPFYAEMGGQIGDKGIIFGKNGEAKVVDCKNNISGKIIHIVQVVKGSIEKNENVTLEVNYKKRKDICKNHTATHMLQAALKKVVGSHINQSGSYVDNERLRFDFTHFTALTDEEILKVEAMVNDEIMAAYDVKTDIMSVDEAKKTGAMALFDEKYGNRVRVVSVGDFSRELCGGTHVNNSGEIGLFKIISESGVAAGIRRIEAITGKEAVRYTEENDNLIRNIEQELKCSKKDILNKINQYHSELKEKEKEINILKGKLASGFEENILSSVKEVSGVKYVASEVKGISGDTLRELCDKVRNKIDDGMVLLASKDGEKVQFVAMASKNAVKKGVHCGKVIKEVASMCGGNGGGRPDMAQAGGKDGEKLETALKEVGNIMEKLVK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SESN3_HUMAN
Sequence: MNRGGGSPSAAANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFIPEKEVVQANTVDERTNFLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITSDVSRYIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHGFSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHEDVDTTMLRRALFNYVHCMFGIRYDDYDYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSYWRQFKHSEKVHVNLLLMEARMQAELLYALRAITRHLT
What is the function of this protein?
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562).  May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity).  This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity).  May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein (By similarity).
What are the official names of this protein?
Sestrin-3.
What is the protein family that this protein belongs to?
Belongs to the sestrin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMIE_BRADU
Sequence: MLHGDISSSNDTVGVAVVNYKMPRLHTKAEVLDNARKIADMVVGMKVGLPGMDLVIFPEYSTQGIMYDSKEMYETASAVPGEETAIFAEACRKAKVWGVFSLTGERHEEHPHKAPYNTLILMNDKGEIVQKYRKIMPWVPIEGWYPGNCTYVSEGPKGLKVSLIICDDGNYPEIWRDCAMKGAELIVRCQGYMYPAKEQQVLISKAMAWANNVYVAVANAAGFDGVYSYFGHSAIIGFDGRTLGECGEEDYGIQYAQLSKHLIRDARRNGQSQNHLYKLVHRGYTGMINSGESPRGVAACPYDFYKNWIKDPEGTRDMVEAMTRSTPGTDECPIEGIPNEAAASNY
What is the function of this protein?
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
What are the official names of this protein?
Aliphatic amidase, Acylamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: ACKA_ACTP7
Sequence: MSKNLILILNCGSSSLKFAVLDPKTGDEKLSGLAEAFNLEDARIKWKLHGEKGNADLGAGAAHSEALTFIANELLSEELKSSIGAIGHRIVHGGEQFTSSVVINDDVVKGIEHAIQFAPLHNPAHLIGIKEAFRIFPELKEKNVAVFDTAFHQTMPEEAFLYALPYKLYKEHGIRRYGAHGTSHLFITSQVAELAGKPVDQTNAIICHLGNGGSVSVVRNGKCIDTSMGLTPLEGLVMGTRSGDIDPAIVFYLYKNLGMSMEQIEDTLVKKSGLLGLTEVTSDCRYAEDNYEDASKPEAKRALDVYSYRLAKYIGAYMAILGDDHLDAIAFTGGIGENSGHVRELALNHLKLFGVKLDVERNLAARFGKSGVITADDSTFKAVVIPTNEELVIAQDTAKLAL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RENI_PANTR
Sequence: MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR
What is the function of this protein?
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
What are the official names of this protein?
Renin, Angiotensinogenase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2.
Protein: TRAC4_ECOLX
Sequence: MAEVKKPFHEQVAERLIEQLKAGTAPWQKPWEPGMPGSFIPLNPTTGKRYKGINAIQLMAQGHADPRWMTYKQAAAAGAQVRRGEKGTPIQYWKFSEEQTKTDEQTGKPVLDANGDPVKVTVQLERPRVFFATVFNAEQIDGLPPLERKEQTWSAVERAEHILAASGATIRHGEHDRAFYRPSTDSIHLPDKGQFPSADNYYATALHELGHWTGHPSRLDRDLAHPFGSEGYAKEELRAEIASMILGDELGIGHDPGQHAAYVGSWIKALQEDPLEIFRAAADAEKIQDFVLAFEQKQIQEQTTQQAIEPAQGATMEQQQDQVARPAIAPADELIAQTLRMYRAGAEPAEGNQSLAALTETTLGFELPADWTGRVQVQANVEVEHDGERSVVPAGDREPEFWGVYANHAWGGHQWLADFAGPDAQTNAEALADRLAVIDAYATANEYEQAAKFARIHEERVRRDPNSTDEDRVAAKEARKAAEGTAMLHDEDLQRRIADYEREQQEMAQAMNAAEQPAAAQAPAKPERAYLNVPFKEKDEVKALGARWDRQERAWYVPAGVDPAPFAKWAREGATAAVEARAEAQPTQPTAERPNAAQERVYLAVPYGERQVAKAAGAQWDKVAKSWYAGPNADMGKLQRWLPDNVPTQQSPAVTPEDEFAEALKSMGCVVTPGGEHPIMDGKKHRIETEGDKKGEKSGFYVGHLDGHPAGYIKNNRTGVEMKWKAKGYALDPAEKAKMQAEAAAKLAARAEEQERQHEATAQRIGRQAQSLVPITEPTPYLRDKGLQVHAGVLTDQEGQKTYIPAYDADGKQWTMQYIQEDGTKRFAKDSRKEGCFHVVGGMDALAAAPALVIGEGYATAATVAEALGHATVAAFDSGNLQAVAEALHAKFPDKPVVIAGDDDRQVQITQGVNPGRTKAQEAAKAVGGKAIFPIFAPGENAYPKELPPITPENYRNHLHAEKRLADAAAGKVQLSEADTAKLKESLLNDGQLAALSNMKKHTDFNDLSERSSLGKDGVERQVRSAVGKVLLDEGQRQKVQQLKQQDIEQQEQRQRRARTY
What is the function of this protein?
Required for autonomous replication in E. coli.  Transferred into the recipient cell during bacterial conjugation.  Catalyzes the synthesis of short oligoribonucleotide primers with CpA or pCpA at their 5'-termini on a single-stranded template DNA.
What are the official names of this protein?
DNA primase TraC, Replication primase.
Protein: UPE21_UPEIN
Sequence: GIVDFAKKVVGGIRNALGI
What is the function of this protein?
Shows a medium antibacterial activity against L. mesenteriodes, M. luteus and S. uberis.
What are the official names of this protein?
Uperin-2.1.
What are the subcellular locations of this protein?
Secreted.
Protein: RS6_CORK4
Sequence: MRHYEIMIILDPAQDERTVAPSLDKYLDVVRKEKGNVDKVDIWGKRRLAYPIQKKEEGIYVVVDFTCESATVLEVDRLLNLNDSVLRTKVLRTDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NAGZ_SALTI
Sequence: MGPVMLNVEGCELDAEEREILAHPLVGGLILFTRNYHDPEQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFFALHGLEEGGRLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPAKALAMATRFIDGMHDAGMKTTGKHFPGHGAVTADSHKETPCDPRPETDIRGKDMSVFRALISENKLDAIMPAHVIYRAIDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERAQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRRELMDSARWKTASAQLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSIT1_PSICY
Sequence: MNPTTATDAHERTSLLSGRPQSAANSTAPYERQVQPSRKSQCFTPVTVITIITLIYRLATTMVITTNIRVLHTVACQLWYHVNDPDVFPGGNIPEKYCALPGVDKYYAIMVSMTTVIDGLGGILGTGIASYMSSRFGRKPVLMFLLSCTMIDHLAILTVQNVYGWKQLVTFGLIMIVETIGNENTTVFLVSMYVVDVTEAERRTAALSSITGWLVLGGALAYSIGGSITTFLHSNSAVYIVSFSVTGIVLTFTAFVLPESFPAEKRDLLRLERLAETRGHSQSWTQKIKAVATVALEPMELLKPTFNPITGKANWRLVYCALHSFIVTLADAYALPAMLIFFTTQYSYTPAQMGYVMTTYSVSSVFVLAIALPLFIRWFKPLYNNTQTKSVPDEGDGLRATDSGEAGVHTQEVVVSETSDRMDVHITVISWTIESLAYIVLGTVGSFYAQLLGRPLPLLALDLDAFQEFEA
What is the function of this protein?
Major facilitator-type transporter; part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product.
What are the official names of this protein?
Major facilitator-type transporter psiT1, Psilocybin biosynthesis cluster transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HEM6_SINMW
Sequence: MERPQLPQGLPADIERKKAEAKAWFESLRDTICADFEAIEDDLAGPLSDRPAGRFVAKDWLRDEGNGGGGRMSMMEGRVFEKVGVHTSTVFGEFSPEFRDQIPGASEDPRFWASGISLIAHPVNPNVPAVHMNTRMVVTTSNWFGGGADLTPVLDRRRIPTDADTVLFHRAMEIACNRHKVADYPKFKQWCDEYFYLKHRNEPRGTGGIFYDWLRSDEEIGGWEADFAFTRDVGKAFAIVYPRIVRTNFNMPWTEQDRSEQLVRRGRYVEFNLLYDRGTIFGLKTGGNVESILSSLPPLVRWP
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_HELPJ
Sequence: MILACDVGLKRIGIAALLNGVILPLEAILRHNRNQASRDLSDLLRKKDIQVLVVGKPNESYADTHARIEHFIKLVDFKGEIVFINEDNSSVEAYENLEHLGKKNKRIATKDGRLDSLSACRILERYCQQVLKKG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRD_ECOLI
Sequence: MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQAVATAIDTHLVSNDFSVLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGSSDLFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIIVMLFLAVRWLQRQLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLREIQNAREQHSRLDTLIRSYAAQDVKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHSQVEEQFFTLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIAGQLIKAVDTLPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEKGRGNVRWRTLIEQMLSRGGPRLYQKPAVTREGQVHHRELMCRIFDGNEEVSSAEYMPMVLQFGLSEEYDRLQISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKSQRKRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELLKLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQGDFFASSQPLDTNVKKYSQRYSV
What is the function of this protein?
Serves as a specificity factor required for RNase E-mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease.  Nor does its activity involve c-di-GMP, despite its domain composition.  Positively modulates motility gene expression, is also required for curli expression.
What are the official names of this protein?
RNase E specificity factor CsrD, Regulator of CsrB and CsrC decay CsrD.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TX216_APOSC
Sequence: EIPQNLGSGIPHDKIKLPNGQWCKTPGDLCSSSSECCKAKHSNSVTYASFCSRQWSGQQALFINQCRTCNVESSMC
What is the function of this protein?
Insecticidal neurotoxin with probable ion channel impairing activity.  In vivo causes a rapid, irreversible flaccid paralysis that results in death.
What are the official names of this protein?
U1-cyrtautoxin-As1c, U1-CUTX-As1c, Aptotoxin VI, Aptotoxin-6, Paralytic peptide VI, PP VI.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HYPA_SHEB9
Sequence: MHEYSIVSALIEQCEQHAQANHADKITRVDIKLGVMSGVEPSLLQTAFDTFKLDGICNAAQLNIQIQPLVILCQDCQTESVLSERTVVCPACQSFRTRVLDGEDMLLMQLEMEQNED
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: ZN717_HUMAN
Sequence: MFPVFSGCFQELQEKNKSLELVSFEEVAVHFTWEEWQDLDDAQRTLYRDVMLETYSSLVSLGHYITKPEMIFKLEQGAEPWIVEETPNLRLSAVQIIDDLIERSHESHDRFFWQIVITNSNTSTQERVELGKTFNLNSNHVLNLIINNGNSSGMKPGQFNDCQNMLFPIKPGETQSGEKPHVCDITRRSHRHHEHLTQHHKIQTLLQTFQCNEQGKTFNTEAMFFIHKRVHIVQTFGKYNEYEKACNNSAVIVQVITQVGQPTCCRKSDFTKHQQTHTGEKPYECVECEKPSISKSDLMLQCKMPTEEKPYACNWCEKLFSYKSSLIIHQRIHTGEKPYGCNECGKTFRRKSFLTLHERTHTGDKPYKCIECGKTFHCKSLLTLHHRTHSGEKPYQCSECGKTFSQKSYLTIHHRTHTGEKPYACDHCEEAFSHKSRLTVHQRTHTGEKPYECNECGKPFINKSNLRLHQRTHTGEKPYECNECGKTFHRKSFLTIHQWTHTGEKPYECNECGKTFRCKSFLTVHQRTHAGEKPYACNECGKTYSHKSYLTVHHRTHTGEKPYECNECGKSFHCKSFLTIHQRTHAGKKPYECNECEKTFINKLNLGIHKRTHTGERPYECNECGKTFRQKSNLSTHQGTHTGEKPYVCNECGKTFHRKSFLTIHQRTHTGKNRMDVMNVEKLFVRNHTLLYIRELTPGKSPMNVMNVENPFIRRQIFRSIKVFTRGRNPMNVANVEKPCQKSVLTVHHRTHTGEKPYECNECGKTFCHKSNLSTHQGTHSGEKPYECDECRKTFYDKTVLTIHQRTHTGEKPFECKECRKTFSQKSKLFVHHRTHTGEKPFRCNECRKTFSQKSGLSIHQRTHTGEKPYECKECGKTFCQKSHLSRHQQTHIGEKSDVAEAGYVFPQNHSFFP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 717, Krueppel-like factor X17.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TVB28_HUMAN
Sequence: MGIRLLCRVAFCFLAVGLVDVKVTQSSRYLVKRTGEKVFLECVQDMDHENMFWYRQDPGLGLRLIYFSYDVKMKEKGDIPEGYSVSREKKERFSLILESASTNQTSMYLCASSL
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 28.
What are the subcellular locations of this protein?
Cell membrane.
Protein: YQGF_LEGPA
Sequence: MPRGVYLGFDFGYKRIGVAVGQRLTCSASPLSTIEAKAGIPDWNTIQKVITQWNPQALIVGLPTCIDDRELYTTSAARHFAKQLHKRFSLPVHLVDERLSTVEARGYLFEQGGYRQIKKAEVDSIAACVILEQWLQQSE
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFPL_ECO5E
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: NADL2_HUMAN
Sequence: MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPATSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKSFRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGYPSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNNLKGDQPNTHQLLAMALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQDMEKSFLVKQAPPGFYRNILYHLDEKTSRFSILIEAWEHCKPLASNETLQEALSEVLNSINSAQVYFKAGLDVFKSVLDGKN
What is the function of this protein?
May be catalytically inactive.
What are the official names of this protein?
Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2, NAALADase L2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: PM34_HUMAN
Sequence: MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKRAHQH
What is the function of this protein?
Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extent for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'-diphosphate (PAP).  May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter-exchange mechanism.
What are the official names of this protein?
Peroxisomal membrane protein PMP34, 34 kDa peroxisomal membrane protein, Solute carrier family 25 member 17.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: ATPBM_HEVBR
Sequence: MASRRLLSSLLRSSSRRSVSKSPISNINPKLSSSSPSSKSRASPYGYLLTRAAEYATSAAAAAPPQPPPAKPEGGKGGGKITDEFTGKGAIGQVCQVIGAVVDVRFDEGLPPILTSLEVLDHSIRLVLEVAQHMGEGMVRTIAMDGTEGLVRGQRVLNTGSPITVPVGRANPWTYHEVIGEPIDERGDIKTSHFLPIHREAPAFVDQATEQQILVTGIKVVDLLAPYQRGGKIGLFGGAGVGKTVLIMELINNVAKAHGGFSVFAGVGERTREGNDLYREMIESGVIKLGDKQADSKCALVYGQMNEPPGARARVGLTGLTVAEHFRDAEGQDVLLFIDNIFRFTQANSEVSALLGRIPSAVGYQPTLATDLGGLQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRQISELGIYPAVDPLDSTSRMLSPHILGEEHYNTARGVQKVLQNYKNLQDIIAILGMDELSEDDKLTVARARKIQRFLSQPFHVAEVFTGAPGKYVELKESITSFQGVLDGKYDDLPEQSFYMVGGIDEVIAKADKIAKESAS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: SYR_AROAE
Sequence: MSADSKVQLTALLRAALKSIAPELADTPIHLERPKQAGHGDFATNLALQLAKPLRRRPRELAELLLAELPRSTLVAATEVAGAGFINFTLAAGAKTAAVGTVLERGAEFGRGARNGTSVQLEFVSANPTGPLHVGHGRGAAYGASLAAVLDFAGSDVTREYYINDAGRQMDILALSTWLRYLALYGLDIPFPPNAYQGDYVVDMARAMREGHQDRFAGFTIEQVLEGAPGLPVAERKDDEAKTQREDHLDMLIANAKRLLGEDYHFVHGFALNEQLGDGRDDLEEFGVHFDKWFSEKSLFDTGLVDRAVAELEKRGHVYLQDGAKWFRSTAFGDEKDRVVQRENGLYTYFASDIAYHLNKYERGYDRIIDIWGADHHGYIPRVKGAIAALGLPPEKLEVALVQFAVLYRNGQKASMSTRSGEFVTLRELRREVGNDACRFFYVLRKSDQHLDFDLDLAKSQSNENPVYYVQYAHARVCSVLEQWGGEAAELRAAQLDLLGNERELALCARLGGFPELIQNAAADHAPHQIAFYLKDLAAEFHSWYNAERMLVDDPALRLARLALATAVRQVLATALALLGVSAPQSM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_SACS2
Sequence: MSSRREIRWGIAHIYASQNNTLLTISDLTGAEIISRASGGMVVKADREKSSPYAAMLAANKAASDALEKGIMALHIKVRAPGGYGSKTPGPGAQPAIRALARAGFIIGRIEDVTPIPHDTIRRPGGRRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RS15_TRIEI
Sequence: MALKQQRKQEIIGEYQTHETDTGSADVQVAMLTEKITKLSAHLRNNKQDYSSQRGLLKMIGKRKRLLTYIQKQNQERYKALITRLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: NUSB_BURM7
Sequence: MKKSARRQSRELATQGLYQWLLSNAAPGEIDAQLRGALGYDKADKTLLDTILHGVIREHATLAEAISPSLDRPIDQLSPVERAVLLIATYELTHQIETPYRVIINEAVELAKTFGGSDGYKYVNGVLDKLAVKLRPAETQARRGA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.