PharMolix/UniProtQA huggingface dataset:
Protein: ORR10_ORYSJ
Sequence: MAVAIEAPFHVLAVDDSLPDRKLIERLLKTSSFQVTTVDSGSKALEFLGLHDHEDSPISTQSDQQEVGVNLIITDYCMPGMTGYDLLKKIKESSYLRDIPVVIMSSDNIPSRINRCLEEGADEFFLKPVRLSDMSKLKPHILKSRCKEHYQQEQHLQSNSESNNSSNPTSENSSSSTSTNSHKRKAVDEEILPHTIRPRHS
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator ORR10, OsRR10, OsRRA2.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL34_CAMJ8
Sequence: MKRTYQPHGTPRKRTHGFRVRMKTKNGRKVINARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SCAF8_HUMAN
Sequence: MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKVPGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKNNVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQLTAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKEIPASQLSHVSESVNNSIFHQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLGRRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSGNYRFDPRSGPWNRGFGQEVHRDFDDRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQNTWVPPPHARVFDYFEGATSQRKGDNVPQVNGENTERHAQPPPIPVQNDPELYEKLTSSNEINKEKSDTVADIESEPVVESTETEGT
What is the function of this protein?
Anti-terminator protein required to prevent early mRNA termination during transcription (PubMed:31104839).  Together with SCAF4, acts by suppressing the use of early, alternative poly(A) sites, thereby preventing the accumulation of non-functional truncated proteins (PubMed:31104839).  Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A), and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation (PubMed:31104839).  Independently of SCAF4, also acts as a positive regulator of transcript elongation (PubMed:31104839).
What are the official names of this protein?
SR-related and CTD-associated factor 8, CDC5L complex-associated protein 7, RNA-binding motif protein 16.
Protein: COAD_MANSM
Sequence: MTKTVIYPGTFDPITYGHLDIIERSAVLFPQVLVAVASNPTKKPLFELAERVRLAEESVAHLPNVQVIGFSDLLANVVKERHITAIIRGMRTTMDFEYELQLAHLNRALTDGVESLFLPSTEKWSYVSSTIVREIYLHRGDVSQFVPPPVLTALMEKNR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_HV1Y2
Sequence: MRATEIRKNYQHLWKGGTLLLGMLMICSAAEQLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLRNATNTTSSSWETMEKGEIKNCSFNITTSIRDKVQKEYALFYNLDVVPIDNASYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVINCTRPNNNTRKSINIGPGRALYTTGEIIGDIRQAHCNLSKTQWENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHSFNCGGEFFYCNSTQLFTWNDTRKLNNTGRNITLPCRIKQIINMWQEVGKAMYAPPIRGQIRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGLGALFLGFLGAAGSTMGAASITLTVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNTSWSNKSLNEIWDNMTWMKWEREIDNYTHIIYSLIEQSQNQQEKNEQELLALDKWASLWNWFDITKWLWYIKIFIMIVGGLIGLRIVFVVLSIVNRVRQGYSPLSFQTHLPAQRGPDRPDGIEEEGGERDRDRSGPLVDGFLAIIWVDLRSLCLFSYHRLRDLLLIVTRIVELLGRRGWGVLKYWWNLLQYWIQELKNSAVSLLNATAIAVAEGTDRVIEILQRAFRAVLHIPVRIRQGLERALL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: PVK1_BLAGI
Sequence: GSSGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, BlaGi-PVK-1, PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH_ENT38
Sequence: MTKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFNEGYHLTTNNRMELMAAIVALEALKEDCDVVISTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWKRLDAALSHHTIKWEWVKGHAGHPENERCDELARAAAMNPIQEDVGYQPGS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_BACVZ
Sequence: MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLTQIRQQAEIAMDEADVIIFMVNGREGVTSADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYALGFGEPYPISGTHGLGLGDLLDACAEHFKNIPETKYSDDVVQFCLIGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTAFTYNQQEFVIVDTAGMRKKGKVYETTEKYSVLRALKAIDRSDVVGVVLNAEEGILEQDKRIAGYAHEAGKAVVIIVNKWDAVDKDERTMKEFEQNIREHFQFLDYAPVLFMSALTTKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVAVKPPSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIFARARK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: IL8_HORSE
Sequence: MTSKLAVALLAVFLLSAALCEAAVVSRITAELRCQCIKTHSKPFNPKLIKEMRAIESGPHCENSEIIVKLVNGAEVCLNPHTKWVQIIVQAFLKRAEGQNP
What is the function of this protein?
Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection.  Also plays an important role in neutrophil activation.  Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells.  G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
What are the official names of this protein?
Interleukin-8, IL-8, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSH1_ECOUT
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: FAEC_ASPTN
Sequence: MAILSRLLTTVTLGSLLTSAVAQSSGCGKQPTLTNGVQNINGREYILNIPEGYDSSKQYKLIFGLHWLGGSMNDVVSGNSIEPWYGLESRAEGSAIFVAPNGLNAGWANNGGEDTALMDAIIEAVEADLCIDQSSRFATGFSFGGGMSYALACARASKFRAVSVLSGGVISGCDGGNDPIAYLGIHGINDPVLPIDGGIEMANKFVQNNGCQSADVGRPNSGSGQSVRTDFQGCSRPVSFIAYDGGHEGAPLGVGNPLAPDATWEFFTGA
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin.  Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan (By similarity).
What are the official names of this protein?
Probable feruloyl esterase C, Ferulic acid esterase C.
What is the protein family that this protein belongs to?
Belongs to the faeC family.
What are the subcellular locations of this protein?
Secreted.
Protein: BGAL_CANLF
Sequence: MARPAAVRVLWALLLPLLLGSARGLRNASQRTFTIDYSHNRFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPQPGQYQFSGEQDVEYFIKLAHELGLLVILRPGPYICAEWDMGGLPAWLLLKESIILRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPIITMQVENEYGSYFTCDYDYLRFLQKLFHHHLGNDVLLFTTDGANEKFLQCGALQGLYATVDFGPGANITAAFQIQRKSEPKGPLVNSEFYTGWLDHWGQPHSTVRTEVVASSLHDILAHGANVNLYMFIGGTNFAYWNGANMPYQAQPTSYDYDAPLSEAGDLTEKYFALREVIRKFEKVPEGFIPPSTPKFAYGKVALKKLKTVEEALNVLCPPGPINSLYPLTFIQVKQYFGFVMYRTTLPQDCSDPTPLSSPLSGVHDRAYVSVDGVPQGVMERSNVITLNITGKAGATLDLLVENMGRVNYGRYINDFKGLISNLTLGSSILTNWMIFPLNTEDAVRSHLGGWHGPNNGRHDKTFAHRSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQMTLFVPRHILVTSTPNTIMVLELEHAPCGDSGPEVCTVEFVDRPVIGAPPTPGHPPPDLSHRDLRLDYV
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
What are the official names of this protein?
Beta-galactosidase, Acid beta-galactosidase, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: NUOD_HELPS
Sequence: MAQNFTKLNPQFENIIFEHDDNQMILNFGPQHPSSHGQLRLILELEGEKIIKATPEIGYLHRGCEKLGENMTYNEYMPTTDRLDYTSSTSNNYAYAHAVETLLNLEIPRRAQVIRTILLELNRMISHIFFISVHALDVGAMSVFLYAFKTREYGLDLMEDYCGARLTHNAIRIGGVPLDLPPNWLEGLKKFLGEMRECKKLIQGLLDKNRIWRMRLENVGVVTPKMAQSWGMSGIMLRGSGIAYDIRKEEPYELYKELDFDVPVGNYGDSYDRYCLYMLEIDESIRIIEQLIPMYAKTDTPIMAQNPHYISAPKEDIMTQNYALMQHFVLVAQGMRPPVGEVYAPTESPKGELGFFIHSEGEPYPHRLKIRAPSFYHIGALSDILVGQYLADAVTVIGSTNAVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: METAS_ECOL6
Sequence: MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLDPDVPYNYFPHNDPQNTPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_BUCBP
Sequence: MNNHTLNIIILAAGKGTRMQFDHPKLLHLLGGKPILEHVINLAQSLCPKTITVIYNKQYKKFKIKNKNNSITWIKQKKILGTGNAISQIINNYKDHENILILYGDVPLISKNSIQKMLLKKKNSTITLLTAKLNNPEEYGRIIRKNKKIVKIIEYKDATDEQLNIKEVNSGILIVSSTNLKKWIFQIHAKNNQNEYYITDIISLANKDNHKINSVRPEKNDEIQGINNLLQLVRAEKIYQKQQAKLLLLSGIMIYNPSNFSLRGTLKHGKNIKIDHGVILEGSVKIGNSVIIEPGCIIKNSTIGNNCTIKAYSIIEKTIISNKCIVGPFTHLQHGTVLKNNTHVGNFVEIKKTTLGSYSKAKHLSYLGNSQIGQKVNIGAGTVTCNYNGKKKLDTIIGDNVFIGSSTQLIAPINIKKGTIIAAGTTVMKNIHEPSLVYNEKKQIHKKL
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP352_ARATH
Sequence: MASSRISLRLVRRFASAAADGTTTAPSSGKISVSKAKSTLRKEHDPDKALKIYANVSDHSASPVSSRYAQELTVRRLAKCRRFSDIETLIESHKNDPKIKEEPFYSTLIRSYGQASMFNHAMRTFEQMDQYGTPRSAVSFNALLNACLHSKNFDKVPQLFDEIPQRYNKIIPDKISYGILIKSYCDSGTPEKAIEIMRQMQGKGMEVTTIAFTTILSSLYKKGELEVADNLWNEMVKKGCELDNAAYNVRIMSAQKESPERVKELIEEMSSMGLKPDTISYNYLMTAYCERGMLDEAKKVYEGLEGNNCAPNAATFRTLIFHLCYSRLYEQGYAIFKKSVYMHKIPDFNTLKHLVVGLVENKKRDDAKGLIRTVKKKFPPSFLNAWKKLEEELGLYSKTDAFPSSAKEAAAA
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g36680, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MNMG_ACIF5
Sequence: MQNSFDVIVVGGGHAGTEAAAAAARLGVRTLLLTQNLDTIGQMSCNPAIGGIGKGHLVKEVDALGGIMALAIDQAGIQFRTLNASKGPAVRATRAQADRSLYKRAVRRLLEDIPALQLFQGMVGDLLMEGDRLGGVILETGLVLRAAQVVLTTGTFLGGRVHMGDQNYPAGRAGDPPSNALAQRLREMAFPVARLKTGTPPRIDGRSIDYGVLEAQPGDAPPPAFSFMTRRIGVPQLACHITHTNARTHEIIQTNLHQSAMYGGHIQSVGPRYCPSIEDKVVRFADKASHQVFLEPEGLDTHEVYPNGISTSLPFGVQIELVRSMRGLENAVLLRPGYAIEYDYLDPRELHPSLESRRLPGLFCAGQINGTTGYEEAAAQGLLAGLNAARRARELAAWTPGRHEAYLGVMVDDLVTRGLDEPYRMFTSRAEYRLQLREDNADLRLTPHGRALGLVDDQRWTAFSAKQDAVQAERNRLEGLRIHPGSAIAGRIAAKTDQPLSRDVTALELLRRPDWDYASLLQVLDLVPCSDAQACEQLEIECKYAGYVARQHDEITRAARWEGTDIPADMDYAAVRGLSTEVMQRLARQRPQTIGLASRIPGVTPAAVSLLLIHVKRRGLRQAG
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_PYRAE
Sequence: MAVRIDGSYGEGGGQILRTSIALSALLGRPVEIVNIRAKRANPGLQPQHLTGVKVAALLTDAEVKGAEKGSTRLYFEPKTLKCGNFSIDIGTAGSISLIVQTLAPILLYAPCPTQITVTGGTDVAWAPPIDYMRFVFTKVLERFGAKLSIELIRRGHYPRGGGRAVVRAEPVKRLKAVESEEFGNVVKISGISHAVNLPPHVAERQAKAAREELSKMGLDADIAIEVRNDGLGPGSGVVIWAVSDAGNVIGGDSLGERGKPAETVGKEAAQKLIAVLKTRASVDPHMADMAVLYMALAEGRSRISTSEETMHLKTNMYIIEQFLRVKFSTMEKAGRYTIEVEGVGYNR
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y151_RICBR
Sequence: MEITMTTAYYRHKYCPDTSYLRPKYIYIPKTPVRKFFESLIPPQIIDSEKWTDLHLAVGYKNIKLVQSVCNKHNINIKDAKGRTALELAILGDNLEIVQFLVQNGGVVAPNNMYGWSAIHLAIKVGNLDIVKYLYENTKFNEHDKYGLTLQNWAEKVGNEQI
What are the official names of this protein?
Putative ankyrin repeat protein RBE_0151.
Protein: RL36_CLOB6
Sequence: MKVRPSVKPICEKCKVIRRKGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: KA261_MESMA
Sequence: MSRLFVFILIALFLSAIIDVMSNFKVEGACSKPCRKYCIDKGARNGKCINGRCHCYY
What is the function of this protein?
Recombinant toxin that reversibly inhibits the potassium current of mKv1. 3/KCNA3 channel stably expressed in COS7 cells (IC(50)=150 nM) (PubMed:17624312).  Also shows a weak inhibition on Kv1. 2/KCNA2, Kv1. 3/KCNA3 and TRPV1 channels (PubMed:29483648).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 26.1, Neurotoxin BmK86.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 26 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PRIN2_ARATH
Sequence: MASMHEALFSSRLLQVNSSFSFRCALPIISSPAAVSCAIKSTQFFKQRCRTKVRDFSLSSLSRRGFVCRAAEYKFPDPIPEFAEAETEKFRDHMLNKLSKRDLFEDSVDEIVGVCTEIFETFLRSEYGGPGTLLVIPFIDMADTLNERELPGGPQAARAAIKWAQDHVDKDWKEWTGTD
What is the function of this protein?
Involved in redox-mediated retrograde signaling to synchronize the expression of photosynthetic genes from both the nuclear and plastidic genomes, especially in excess light conditions (PubMed:22211401).  Required for full expression of genes transcribed by the plastid-encoded RNA polymerase (PEP) (PubMed:22211401, PubMed:25161659).  Essential for embryo development (PubMed:25161659).
What are the official names of this protein?
Protein PLASTID REDOX INSENSITIVE 2, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma, chloroplast nucleoid.
Protein: USPA_PHOLL
Sequence: MAYKHILVAVDLSPESQVLVRKAVSMAKPDNAKVSLIHVDVNYSDLYTGLIDVNLGDMQQRISEETRSALKALSADSAYDIQETLSGSGDLGQVLVDAIKKYGIDMVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDDE
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein A.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPKA_RABIT
Sequence: MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES
What is the function of this protein?
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
What are the official names of this protein?
cAMP-dependent protein kinase inhibitor alpha, PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform.
What is the protein family that this protein belongs to?
Belongs to the PKI family.
Protein: TYSY_YERPE
Sequence: MKQYLDLMKKVLEEGTPKADRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLNGDTNIAYLKENNVSIWDEWADENGDLGPIYGKQWRAWGAADGRKIDQLSNVVNQLKQDPDSRRIIVSAWNVGELDQMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLAVGDFVWTGGDTHLYSNHIDQAHLQLSREPRVLPKLVIKRKPDSLFDYHFDDFDIEGYDPHPGIKAPIAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX2_CHRVO
Sequence: MKFKRYLQVTKPGIIFGNLISAAGGFLLAAQGSVDWWLLAATVVGLSLVVASGCAINNCIDQDIDAKMARTQKRVLVTGAMSTKAALAHGVVLGLAGFALLWFCTNPLATGCVLFGFVIYVGVYSLYMKRNSVYGTLVGSLSGAVPPVAGYCAVTGRFDMGAAILLLMFSLWQMPHSYAIAIFRFKDYEAAGIPVLPVVKGISAAKQQIVLYILAFAAATVMLVFGGYAGYGYLAVAVATSLWWLKMALSGYKRETDDRAWARQVFFFSIITITSLSVMMAVDGQTPPHSRAVMTADAGHYG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.