PharMolix/UniProtQA huggingface dataset:
Protein: CFA58_HUMAN
Sequence: MAEEKGGKQVLEESAFEEMERDFQGVLHELSGDKSLEKFRIEYERLHAVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEIKKLRREKGILARSMANVEELRQEFFHMQRELLKERTRCRALEEELENPLNVHRWRKLEASDPNAYELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYMELKHVLARQPGPEAAEQLKLYRRTLHDKKQQLKVLSSELNMYEVQSKEYKYEVEKLTNELQNLKKKYLAQKRKEQLQKNKDTAPMDNTFLMVKPNGPGFTGGGFPLRSTKMTF
What is the function of this protein?
Has an essential role in the assembly and organization of the sperm flagellar axoneme (PubMed:32791035).  Required for the elongation of the primary cilium and sperm flagellar midpiece via modulation of the Notch signaling pathway (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 58, Coiled-coil domain-containing protein 147.
What is the protein family that this protein belongs to?
Belongs to the CFAP58 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized to the entire flagellum and predominantly concentrated in the midpiece. Co-localizes with ODFP2 at the centrosome (By similarity).
Protein: HEMT_THEDY
Sequence: GFPIPDPYCWDISFRTFYTIVDDEHKTLFNGILLLSQADNADHLNELRRCTGKHFLNEQQLMQASQYAGYAEHKKAHDDFIHKLDTWDGDVTYAKNWLVNHIKTIDFKYRGKI
What is the function of this protein?
Hemerythrin is a respiratory protein in blood cells of certain marine worms.  The oxygen-binding site in each chain contains two iron atoms.
What are the official names of this protein?
Hemerythrin.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: SYK_BACTN
Sequence: MNILELSEQEIIRRNSLNELRAMGIDPYPAAEYVTNAFSTDIKAEFKDEDEPRQVSVAGRIMSRRVMGKASFIELQDSKGRIQVYITRDDICPGEDKELYNSVFKRLLDLGDFVGIEGFVFRTQMGEISIHAKKLTVLAKSIKPLPIVKYKDGVAYDSFEDPELRYRQRYVDLVVNEGIKETFEKRATVVRTLRNALDEAGYTEVETPILQSIAGGASARPFITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYVQYKDYNWMMSFTEKLLERICIAVNGSTETVVDGKTISFKAPYRRLPILDAIKEKTGYDLNGKSEEEIRQICKELKMEEIDDTMGKGKLIDEIFGEFCEGSYIQPTFITDYPVEMSPLTKMHRSKPGLTERFELMVNGKELANAYSELNDPLDQEERFKEQMRLADKGDDEAMIIDQDFLRALQYGMPPTSGIGIGIDRLVMLMTGQTTIQEVLFFPQMRPEKVIKKDPAAKYMELGIAEDWVPVIQKAGYNTVADMQDVNPQKLHQDICGINKKYKLELTNPSVNDVTEWINKLK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y006_CHLTR
Sequence: MPSTVAPIKGQDHFLNLVFPERVAAAYMSPLAQKYPKAALSIASLAGFLLGILKLITFPVLCAAGLFVFPIRGLISCLFHKSFQGCSGYVLATFLSLFSLALTIVGIVSCITWAPGFIFPMISVSIAFATVETCFQIYTHLFPALEHKPSSSLKIEIAAAKLPRSSSAPDLNYPSLPTQSASPSQRFSA
What are the official names of this protein?
Uncharacterized protein CT_006.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0442/CT_006/TC_0274 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOZ_DESDA
Sequence: MARITVEDCQERVDNRFLLVQMAIKRVHQYREGYEPLVESRNKEVVTALREIAAGKVLPDDDALYTPPAEQAAAVNEG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RPOY_LACDB
Sequence: MIYKVLYQKDKIVNPRRETTQTLYMEADNIVQARALVEQNTPYNIELIQELTGNSLKYEQEHADFKLTAFGQTNSED
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: CARB_ARATH
Sequence: MRNHCLELSSNCSSIFASSKSNPRFSPSKLSYSTFFSRSAIYYRSKPKQASSSSSFSTFPPCLNRKSSLTHVLKPVSELADTTTKPFSPEIVGKRTDLKKIMILGAGPIVIGQACEFDYSGTQACKALREEGYEVILINSNPATIMTDPETANRTYIAPMTPELVEQVIEKERPDALLPTMGGQTALNLAVALAESGALEKYGVELIGAKLGAIKKAEDRELFKDAMKNIGLKTPPSGIGTTLDECFDIAEKIGEFPLIIRPAFTLGGTGGGIAYNKEEFESICKSGLAASATSQVLVEKSLLGWKEYELEVMRDLADNVVIICSIENIDPMGVHTGDSITVAPAQTLTDREYQRLRDYSIAIIREIGVECGGSNVQFAVNPVDGEVMIIEMNPRVSRSSALASKATGFPIAKMAAKLSVGYTLDQIPNDITRKTPASFEPSIDYVVTKIPRFAFEKFPGSQPLLTTQMKSVGESMALGRTFQESFQKALRSLECGFSGWGCAKIKELDWDWDQLKYSLRVPNPDRIHAIYAAMKKGMKIDEIYELSMVDKWFLTQLKELVDVEQYLMSGTLSEITKEDLYEVKKRGFSDKQIAFATKTTEEEVRTKRISLGVVPSYKRVDTCAAEFEAHTPYMYSSYDVECESAPNNKKKVLILGGGPNRIGQGIEFDYCCCHTSFALQDAGYETIMLNSNPETVSTDYDTSDRLYFEPLTIEDVLNVIDLEKPDGIIVQFGGQTPLKLALPIKHYLDKHMPMSLSGAGPVRIWGTSPDSIDAAEDRERFNAILDELKIEQPKGGIAKSEADALAIAKEVGYPVVVRPSYVLGGRAMEIVYDDSRLITYLENAVQVDPERPVLVDKYLSDAIEIDVDTLTDSYGNVVIGGIMEHIEQAGVHSGDSACMLPTQTIPASCLQTIRTWTTKLAKKLNVCGLMNCQYAITTSGDVFLLEANPRASRTVPFVSKAIGHPLAKYAALVMSGKSLKDLNFEKEVIPKHVSVKEAVFPFEKFQGCDVILGPEMRSTGEVMSISSEFSSAFAMAQIAAGQKLPLSGTVFLSLNDMTKPHLEKIAVSFLELGFKIVATSGTAHFLELKGIPVERVLKLHEGRPHAADMVANGQIHLMLITSSGDALDQKDGRQLRQMALAYKVPVITTVAGALATAEGIKSLKSSAIKMTALQDFFEVKNVSSLLV
What is the function of this protein?
Subunit of the carbamoyl-phosphate synthetase (CPS) composed of a small chain CARA/VEN6 and a large chain CARB/VEN3.  Involved in arginine biosynthesis.  Required for mesophyll development.
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, chloroplastic, Carbamoyl-phosphate synthetase ammonia chain, Protein VENOSA 3.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS5_HERA2
Sequence: MIAVINYGAGNLPNAVRALEYVQAPIEVVTDPAAVRAAQAVVLPGVGATADTMRSLREMGMDSAIREVIARGTPFLGICVGMQVLAEQSEEFGLHECLGLVPGTIRRFDQGLKVPQIGWNGVQHDGSALWDGIPNGAEFYFVHSYYLATDDVALVTGRTEYGLNFPAAIARDNITAVQFHPEKSGQWGLKLLGNWVELALSRGSGVGDRA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1553_AERS4
Sequence: MALDIKLLDIIACPVCKGKLHYNKAVHELVCRFDKLAYPLEEGIPVLLENRARQLNSDEMPS
What are the official names of this protein?
UPF0434 protein ASA_1553.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: GLMM_HAEIE
Sequence: MANRKYFGTDGVRGKVGAYPITPDFALKLGWAAGKVLSSQGSKMVLIGKDTRISGYMLESALEAGLAAAGLSAAFTGPMPTPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSAKGTKLPDEIEEAIEAMLEQPMDCVESAELGKASRINDAAGRYIEFCKGTFPAHLGLEGYKIVIDCANGATYHIAPNVFRELGAEVIEIGTDPNGLNINEKCGATDVTALQAKVVETKADVGLAYDGDGDRIMMVDHLGNKVDGDQILFIIAREALRSGQLKGGVVGTLMSNMSLEIALKMLGVPFLRANVGDRYVLEKMLENDWTLGGENSGHIIIADKNTTGDGIVASLAVLAAMAQHKLSLNELASAVKLFPQVLINVRFAGGENPLESDAVKSVAAEVEKRLEGKGRILLRKSGTEPLIRVMVECQDAELAQQCAEEIAEAVKKIN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: APT_MACCJ
Sequence: MDLKQYITQVKDWPKPGVNFKDITTIMDNGAAYKYATDQIVEYAKEKQVDIVVGPEARGFIIGCPVAYAMNIGFAPVRKKGKLPREVISYEYELEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEATIKLVESLGGIVAGIAFIIDLKYLNGMEKLKGYDVISLVEYEVE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODL_VACCU
Sequence: MAVCIIDHDNIRGVIYFEPVHGKDKVLGSVIGLKSGTYSLIIHRYGDISRGCDSIGSPEIFIGNIFVNRYGVAYVYLDTDVNISTIIGKALSISKNDQRLACGVIGISYINEKNNTFSYN
What is the function of this protein?
Superoxide dismutase-like protein with no enzymatic activity.
What are the official names of this protein?
Cu-Zn superoxide dismutase-like protein OPG175.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PPIB_MOUSE
Sequence: MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPFAIAKE
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Melanosome.
Protein: RL27_STRSY
Sequence: MLNLNLANLQFMAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSGGSILYRQRGTKIYPGANVGRGGDDTLYAKVEGVVRFERKGRDKKQVSVYPIAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: C7A12_MEDTR
Sequence: MEPNFYLSLLLLFVTFISLSLFFIFYKQKSPLNLPPGKMGYPIIGESLEFLSTGWKGHPEKFIFDRMRKYSSELFKTSIVGESTVVCCGAASNKFLFSNENKLVTAWWPDSVNKIFPTTSLDSNLKEESIKMRKLLPQFFKPEALQRYVGVMDVIAQRHFVTHWDNKNEITVYPLAKRYTFLLACRLFMSVEDENHVAKFSDPFQLIAAGIISLPIDLPGTPFNKAIKASNFIRKELIKIIKQRRVDLAEGTASPTQDILSHMLLTSDENGKSMNELNIADKILGLLIGGHDTASVACTFLVKYLGELPHIYDKVYQEQMEIAKSKPAGELLNWDDLKKMKYSWNVACEVMRLSPPLQGGFREAITDFMFNGFSIPKGWKLYWSANSTHKNAECFPMPEKFDPTRFEGNGPAPYTFVPFGGGPRMCPGKEYARLEILVFMHNLVKRFKWEKVIPDEKIIVDPFPIPAKDLPIRLYPHKA
What is the function of this protein?
Catalyzes the carboxylation of beta-amyrin at the C-28 position to form oleanolic acid.  Involved in an early step in the hemolytic saponin biosynthetic pathway (PubMed:21821776, PubMed:22039103, PubMed:23378447).  Catalyzes the carboxylation of alpha-amyrin and lupeol at the C-28 position to form ursolic acid and betulinic acid respectively (PubMed:22039103).
What are the official names of this protein?
Beta-amyrin 28-monooxygenase, Beta-amyrin 28-oxidase, Cytochrome P450 716A12, MtCYP716A12, Protein LACKING HEMOLYTIC ACTIVITY.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SPTSB_HUMAN
Sequence: MDLRRVKEYFSWLYYQYQIISCCAVLEPWERSMFNTILLTIIAMVVYTAYVFIPIHIRLAWEFFSKICGYHSTISN
What is the function of this protein?
Stimulates the activity of serine palmitoyltransferase (SPT).  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs.  The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.  May play a role in signal transduction.
What are the official names of this protein?
Serine palmitoyltransferase small subunit B, Protein ADMP, Small subunit of serine palmitoyltransferase B, ssSPTb.
What is the protein family that this protein belongs to?
Belongs to the SPTSS family. SPTSSB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DTD_LEUCK
Sequence: MKVVLQRVKSAQVTIDNQIVGAIKQGYVLLVGIENTDTAEDIMYLVRKISQLRVFEDESGRMNLSIQDIEGTFLSISQFTLLANTKKGNRPSFTGAGDPVFAEKLYANFNDQLRLYSGLDVETGQFGADMAVSLVNDGPVTILFDTHQK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD_SHEDO
Sequence: MKPASTRLLAINAVSKVFHDGACETQVLHEVNLTVHRGEQLAIVGSSGSGKSTLLHIMGTLESPTSGTVLLEGENLHQLSSKRQAQIRNQDLGFIYQFHHLLPEFSALENVAMPAFIQGKNKAQTLAEAKALLERVGLGHRLTHLPSQLSGGERQRVAIARALINKPKLVLADEPTGNLDAVSGEAVYGLIRELAEQLGTAFVVVTHDANLAARMDRQVNMKDGILSQSETHR
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NADK_SHEPC
Sequence: MGINFDVSRPKARSSINMTTKFHTIGLIGKPHHLGTNQTLKRLHHWLTMQGYEVLAEERVSTELGTNIEAVDLLEIGARCDLAIVVGGDGNMLGAARVLARFDLGVIGVNRGNLGFLTDLPPDAFEEALARVLDGEFDTEHRFLLEAEVYRHGMLKASNTAVNEAVLHPGKIAHMIEFEVYIDDQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVDACSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIIRRSSERLRLIHPKGHNYFHVLRTKLGWGSKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_ECO24
Sequence: MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFADEGLNVMLVGDSLGMTVQGHDSTLPVTVEDIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_FRATF
Sequence: MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRINSYFSKGAKDSKTLMMVEQIARIEITITPSDYEAYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCENSYYKSRVRPCLQYQIKRCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISAKMYQASEDMEYEKAQVYRDQLVVLRKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKNIILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLESEKDIKRIECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQAEAVFREYGIQDKVQLVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSIIEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_PECCP
Sequence: MTDVTVKSLAAEIQTPVDRLIQQFADAGMTKSASDAVTQHEKETLLAHLNRDRGNAQGKLTLQRKTRSTLNVPSTGGKSKSVQIEVRKTRTYVKRDPIDAQQAEEEEQARREAEEQAQRAAEEQAKREAELREAAEKAKRAADEQAKREAAEKAKRDVAEKEKVTNQQNENMTKPAQAEKAKREAEAAELKRKAEEAARLKVEEEARRIAEEARRMAEENAGRWEAESAKPEESADYHVTTSHHAREAEDENDRQVEGERRSRSRAGKVTKQKKGNRQSESKADREEARAVTRGGKGKRKPSSLQQSFNKPVQAVNRDVVIGETVTVAELANKMAVKGSQVIKVMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGVAAEARAPVVTIMGHVDHGKTSLLDYIRSTKVAAGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTAMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKTELSQYGVMPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRSGMANGVVIESFLDKGRGPVATVLVREGTLNKGDIVLCGFEYGRVRAMRDELGREITSAGPSIPVEILGMSGVPAAGDEATVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVSELNIVLKSDVQGSCEAISDSLQKLSTDEVKVKIVGSGVGGITETDATLAAASNAIILGFNVRADASARRIVESESLDLRYYSVIYDLLDEVKQAMSGMLAPEYKQEIIGLAEVRDVFKSPKFGAIAGCMVTEGIVKRHNKIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRPGDMIEVFETIEIKRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFB36_MOUSE
Sequence: MKLLLLTLAALLLVSQLTPGDAQKCWNLHGKCRHRCSRKESVYVYCTNGKMCCVKPKYQPKPKPWMF
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 36, BD-36, mBD-36, Defensin, beta 36.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENY2_XENLA
Sequence: MNKDAQMKAVINQKLIETGERERLKELLRAKLIECGWRDQLKAHCKDVINEKGVEHVTVDDLVAEITPKGRALVPDSVKKELLQRIRAFLAQHASL
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histones.  The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor ENY2, Enhancer of yellow 2 transcription factor homolog.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: DEGA_BACSU
Sequence: MKTTIYDVAKAAGVSITTVSRVINNTGRISDKTRQKVMNVMNEMAYTPNVHAAALTGKRTNMIALVAPDISNPFYGELAKSIEERADELGFQMLICSTDYDPKKETKYFSVLKQKKVDGIIFATGIESHDSMSALEEIASEQIPIAMISQDKPLLPMDIVVIDDVRGGYEAAKHLLSLGHTNIACIIGDGSTTGEKNRIKGFRQAMEEAGVPIDESLIIQTRFSLESGKEEAGKLLDRNAPTAIFAFNDVLACAAIQAARIRGIKVPDDLSIIGFDNTILAEMAAPPLTTVAQPIKEMGAERHRTAGRSNRGKRKAKQKIVLPPELVVRHSTSPLNT
What is the function of this protein?
Involved in the control of degradation of B. subtilis amidophosphoribosyltransferase (purF).  Probably activates the gene for a degradative protease.
What are the official names of this protein?
HTH-type transcriptional regulator DegA, Degradation activator.
Protein: RTCA_TRIV2
Sequence: MIDIDGSYGEGGGQVLRTSLSLAAITGEPIRIAGIRAGRRKPGLAAQHLTAVRAAARICHGELQGDALGSTMLEFIPGGGVKAGNYIFDVSEVQQGGSAGAITLVLQTILLPLALADGDSHITLRGGTHVIFSPTVTYIERVYLPMLCRMGIKAQVKLGAWGWYPRGGGEVNLQVKGGCQLCGLNLLERGELKRVQGLAVATELPAHIPQRMANRAENLLRTAGLRVSMQALREKGVAPGAGIFLTAEYCNSLTGFGGFGRLRLSSEKVAEIACGQLLQFHETGAPVDEHLADQLLLPAALASESSQYRVAEVSTHLTTNAAVIEKFGLGKITVNQAERVVAIASDKT
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEZF1_XENLA
Sequence: MDSSLQHSTTKILSTQESREALSNRLTMISGAKPLAFSIERIMSRTPEPKCLPVASLLQSSAPKGDQKPGLHINSSSIPRMIPFVPVAYEHCAKIGISGAELRKSHVDSSPPFSCSDLLNCALTLKGDFPREALPLQQYKLVRPRVVNHSSFHAMGAAFCYFNRGDSEWHPPASINIHPMASYFLGSPLHQAPKCYVAAERNKLLAPSVEKFPSGVTFKDLSQAQFQHYMKEGPRSLSDKITFKTSAKFSSASPSSKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKICGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQIYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDNSGSSAGTRGLGATGHQELHLPNREQSHTIIQSPQLQKSVY
What is the function of this protein?
Transcription repressor.  Involved in the development of the forebrain region.
What are the official names of this protein?
Fez family zinc finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUA_STRMU
Sequence: MIRYKAIISYDGTNFSGFQRQPQVRTVQEEIEKTLLRLNSGQAVKIHGAGRTDAGVHAYGQVIHFDLPQQRDLEKLRFGLDTQTPDDIDVIQVEQVADDFHARYQKHRKTYEFLVDLGRPKNPLMRHYATHFPYKVDFSVVKAAIKKLRGTHDFTGFTASGTSVENKVRTISRATVEKDDKTGFLIFTFTGSGFLYKQVRNMVGTLLKIGNGRMPIDQIDRILESGDRSLAGPTAASNGLYLKEIIYDD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.