PharMolix/UniProtQA huggingface dataset:
Protein: GCSH_VIBVY
Sequence: MDKTLKFTESHEWVRDNGDGTVTIGISEHAQEMLGDVVFVELPELEAEIEAGESFSLVESVKAASDIYAPVTGEVVEVNEELSDSPELINEEPYEGGWIVKVKLSDPSELDNLKDAEEYLNSIEED
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ATPA_CAMC1
Sequence: MSAKIKADEISTIIKERIENFDLSVDVEETGKVISVADGVANVYGLKNVMAGEMVEFESGEKGMALNLEESSVGIVILGKTSGITEGSSVKRLKKLLRVPVGDALIGRVVNSLGEPIDAKGPIEATESRFVEEKAKGIMARKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTVAIDTIINQKGQDVICIYVAIGQKQSTVAQVVKKLEEYGAMDYTIVVNAGASDAAALQYLAPYAGVTMGEYFRDNSRHALIIYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLNDALGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESDLFNSGIRPAINVGLSVSRVGGAAQIKAIKQVSGTLRLDLAQYRELQAFAQFASDLDESSRKQLERGQKMVEVLKQPPYSPLPVENQVVIIFAGAKGYLDDVATANVTKFEAELYPYIEAKYPEIFEQIRTKKVIDKEVEEILHKALKDFKATFAAN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NOG2_HUMAN
Sequence: MVKPKYKGRSTINPSKASTNPDRVQGAGGQNMRDRATIRRLNMYRQKERRNSRGKIIKPLQYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVMKDPYKVVMKQSKLPMSLLHDRIRPHNLKVHILDTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQGKDRDLVTEDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ
What is the function of this protein?
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (PubMed:32669547).  May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195).
What are the official names of this protein?
Nucleolar GTP-binding protein 2, Autoantigen NGP-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
Protein: Y170_LISW6
Sequence: MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMESRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEVQDY
What are the official names of this protein?
UPF0145 protein lwe0170.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PYR5_PSETP
Sequence: MTSSAAAIRLGFEPFVNASPVELRTNWSDSDVQAVISATYRQVFGNEHLMLSERLTSAESLLASGNISVREF
What is the function of this protein?
Rod linker protein, associated with phycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity).
What are the official names of this protein?
Phycobilisome 37.5 kDa linker polypeptide, phycocyanin-associated, rod, L-37.5/R.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with phycocyanin.
Protein: US05_HCMVO
Sequence: MRTQRAGLSAIVATYRYQLATGIVYRDISSTIATEKKIPFVENAVLKERAFIETIKQHQEPQRRIPRPVDSYVMLHSNARITTSRVIPQHRYKVTAKNPCRSIKRNAFQTAPSQTQSFISVNNRWLG
What are the official names of this protein?
Uncharacterized protein US5.
Protein: CYTB_OPLFA
Sequence: MSMMCGGISAPLDADEDIQKMCDNVKPHAEEKAGKKYDVFTAKTYTTQIVSGTNYFIKIHVGGDDHVHLRVYKKLPCHGGGLELSGMQHSKSLQDPIAYF
What is the function of this protein?
Thiol protease inhibitor.  Has papain inhibitory activity in vitro.  May be involved in immune responses against invading Gram-negative bacteria.
What are the official names of this protein?
Cystatin-B, RbCyt-B, Stefin-B.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB3_NOSS1
Sequence: MATNTSTLNSTETVLRTENLNVYYGKFLALQNIWLDIPKNKVTAFIGPSGCGKSTLLRCYNRLNDLIESFRAEGKIFYYSKNLYAQDIDPVEVRRRIGMVFQRPNPFPKSIYDNIAFGAKINGYKGNMDELVERSLRKAALWDEVKDKLRQSGASLSGGQQQRLCIARAIAVQPEIILMDEPCSALDPISTLRVEELIHELKEQYTIVIVTHNMQQAARVSDRTAFFNVRPTETGGRIGYLVEYDATESIFNNPKQEDTRDYVSGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 3, ABC phosphate transporter 3, Phosphate-transporting ATPase 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YN11A_YEAST
Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYQQQCMMTQNQANPSGWSFYGRPSMIPYTPYQMSPMYFPPGPHSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFLNWVKTYIKFLQNSNLGDIIPTATRKAVRQMTDDELTFLCHTFQLFAPSQFLPTWVKDILSADYTDIMKILSKSINKMQSDTQEVNDITTLATLHYNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLRYARHRYIHMTVADLFSDIHSMYEEQQESKRNKSTYRRNPSDEKKDSRTYTNTTKPKSITRNSQKPNNSQSRTARAHNVSTSNNSSGPDNDLIRGSTTEPIQLKNKHDLHLRPGTY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-NL1 Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS7A_BCHK9
Sequence: MRFFLLLCFFLPCFQAINLGLKVLELCTTGSCISQSASCVTGDIVNVTQVDRTHVVMCADFRHIKYTDVGRTFRIKFSDVTCSWENTSPADVVFPGNHILQFTVLGVCFDNKVVGGCQNINEPCPEPHTVFHLQREDITLLELCVQAAGFNAQDVGVKYDFSLRHKNCLRYKRTLPPHEVVDEDY
What are the official names of this protein?
Non-structural protein 7a, ns7a, Accessory protein 7a.
Protein: NUDC_PSEAB
Sequence: MAGESRWQAGRPTTAQVGGWVLAHCQQRFLQDDNGLLFPREWLKRQELPLLAEHGVGHWQGEPVYVLELDEPIELPGMAWAPLRQFMLHGDFDQFCMLGYASQIGIWARHNRFCGNCGTRMQAQDHERVMQCPQCGLHQYPRLSPSMIVLVTRGDEVLLARSPRFVPGVYSTLAGFVEAGESVEQCVVREVREEVGVEVANLEYIGSQNWPFPHSLMLGFHAEYVSGEIVPQEDEIEDAQWFSLDALPPLPAQRSIARHLIDLYLARRSGAAEPVLPG
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: SIMC1_RAT
Sequence: MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVDFIDLTRETRTRAKDRNGLCVIDLTRSEEENRPIATLDLTLEPVASSQKEPPSLQTCTNLSGKEMIEAQGDRGTQPAAQRVINNDPVDLDLLEENMFEGSRPPTSISQDSVYPPEPNCSSITYKGDLSFLTSLQLSSDVSPFSSTSNNSSSSSNQRTSLPCPQQDVPCQSQGLLCSLQALSYPLRGSPCPPRASSCPPQALSCPPQALSSLSCPSQTVQCQLQALPQPPQEVPCSTQNVPCPQQNIPSTPQDLPWHPRHPLYPSQDTLGLPQDVPGRPQNVSYPQDMTQLQDMPWSLQDMPLSLQDVLQSLQDVPPLLGDVPQSPEVMQLPGYMTQSSRNVIQSSAGVIRSSGGVMQPSGCMMQPSGGVTQSLRSAIQSSGGVMQSSGVTQSLRSVMQSSGGVMQSSGVTQSSGGVTWSLRSVMQSSGCMMQSPGGVMLSAGDMMQSSGGATRSLRSMMQSSGCMMQSPGGVTQSSGSVMQSLRNVIQSSGGVTQSSGGVIQSSSGVPQSLRDRMQSPGSVSQSSGDVIQSPRGASPASGDVIKSQGGMPRSLRDRMQSPGGVPQSSEDVIQSAGGVSPASGDAIQSPGGVSPASGDAMQSSGGVTPSLGDVPQSSGGVSPASGDAMQSPGGVTPSLGDAMQSPGGVSPASGDAMQSPGGVSPSLGDVPQSPGNMLESLGNTPNLSGDVSHVPQELLDLAKGRPKLSLNAVQNRHSPMTISAPSSPSCSANPLSQQSEFSSEKRPWLTVSNSSAREERSLPQSATPGSAQIQGQIAQAGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIIQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENALTPPQDETQTSPGPGVLKTSSDHLSPQPNLARNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQALYFLNNSTSLLKCQSDKSQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVVDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASER
What is the function of this protein?
Inhibits the protease activity of CAPN3.
What are the official names of this protein?
SUMO-interacting motif-containing protein 1, Platform element for inhibition of autolytic degradation.
Protein: LPXC_ALBFT
Sequence: MLQQRTLKSLTHAVGVGLHSGQRVEITLRPAPPDTGIVFRRVDLPQVVEIAVSATAVSDTTMASTIASGNVKVHTVEHLMSACAGLSVDNLYVDITAEEVPILDGSAASFVFLLQSAGIVMQNAPRRFVRLTQTVEVREGSGATEKWARLAPYHGYQLSFEIDFDHPAVDATGQRVVFDMSSGSYAKDIARARTFGFTKDVEMMRAKGLALGGGLDNAIVMDDYKILNAEGLRYDDEFVKHKILDAMGDLYLLGKPLLANYSARRSGHALNNLLLRELLRRTDAWEVVTFEDAERAPRGFAQLAPAW
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: MU157_SCHPO
Sequence: MKYWQAILFFLFGIAFANNLNIPWKACPNYKTYSGRRHYPATGPLRLPFQRPATSCRTFHSKSVEQTIEDVKEQLEDEDLARLFENCMPNTLDTTIRWHAADSHNPQTLVITGDIPAEWIRDSANQLLPYLPLAKSDSPLATLILGAIQTQAEMLIQFPYCNAFQPPKQSFLSGNDNGQSDRVTPAYDPAVVFECKYELDSLASFLKLSYTYWLYTKDQSIFTVKWLAAVERIIQVLEEQSSPSFDEKTGLPKDPVYTFLRNTDSGTETLGLAGRGFPLNANASLIRSAFRPSDDACVLQYFIPANAMMVVELSHLNQMLQASGHADIARTALVWANKIQKGIDQHGIVDHPKFGKVYAYEVDGYGSILFMDDANVPSLLSLPYLGFVERDDPVYVNTRKMILSSEGNPYYLKGKVISGIGGPHIGLRNVWPMSLIVQALTSDDDDEIMSLLDVLKHSTAGLGLMHESVDVSSFKSFTRPWFSWANSLFAELILDLLERKPHLLKKNAS
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 157 protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL2_PSEA6
Sequence: MPLLKAKPTSAGRRHVVQVVNPDLHKGAPYAPLLEKNSKSGGRNNNGRITVRHVGGGHKQHYRVIDFKRNKDGIPAKIERLEYDPNRSANICLVLYADGERRYILAPKGAKAGDQIQSGSDAAIKAGNSLPMRNIPVGTTVHAIEMKPGKGAQIARSAGQYAQILARAEGYVTLRLRSGEVRRVLADCRATIGEIGNAEHMLRSLGKAGANRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGVPTKGKKTRSNKRTDKLIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: LAC_PIG
Sequence: QPKAAPTVNLFPPSSEELGTNKATLVCLISDFYPGAVTVTWKAGGTTVTQGVETTKPSKQSNNKYAASSYLALSASDWKSSSGFTCQVTHEGTIVEKTVTPSECA
What are the official names of this protein?
Ig lambda chain C region.
Protein: RL18_HAEIN
Sequence: MDKKSARIRRAARARHMMREQGVTRLVIHRTPRHIYAQVIAPNGSEVLAAASTVEKAIREQVKYTGNKDAAAAVGKAVAERALAKGVQAVAFDRSGFKYHGRVQTLADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: EIF3D_BOVIN
Sequence: MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDETSFQLVDTARTQKTAYQRNRMRFAQRNLRRDKDRRNMLQFNLQTLPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGKERYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSDEDDEEEEEEEEEEEEEEA
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.  In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d, Eukaryotic translation initiation factor 3 subunit 7, eIF-3-zeta.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_METM5
Sequence: MVKVAVTGALGRMGSGIIKTITETDGLDVVAAIDIPNHPKKGLDIGELTGVGKIGVALSTSDELEVVLKESGAEVLVDFTAPAPCVNTAKTAAKLGVNLVIGTTGFTSEQRAEMENAISENKVAATISQNYAVGVNIFFKTLELLAQKLGDYDIELIEMHHKFKKDAPSGTALRAAEIIQNNLNRDSNLIFGRKGITGERTKEEICIHALRGGDVVGDHTAMFAADGERLELTHKASSRQSFISGVILAVKFVAEKKEGIYNTFDVLDLN
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF2M_HUMAN
Sequence: MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLHSIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFSENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFLQWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQHVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIETSSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPGTSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQTRQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNRRSGLT
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Acts in collaboration with MRRF.  GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2, Elongation factor G2, hEFG2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Protein: RL29_UREU1
Sequence: MSSIAQDLRKKDSLELEKIVIELKAKLLELRFAAANGEAEKLHTAKEIRKTIARALTILNERELAEKLNNKEANK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ATD22_SCHPO
Sequence: MRRRARSIRFSSDDNEDNEEDDDYYSNAHSEKSEDHSNHIKVSHFDPSSYKQKLVSVRETQRNRKFSSLQKHLNTETPSFSVSIENPSKPSAAFNDASLGKKSTEHQIDGIRNGSSNLQMEGNDKELDTDNNEDESTTFKDEEDDLISPKSYLTSSKTFSYPKAPTESTNGDYLDEDYVDGQSDPESSNASDSDFADSPDDLTKVRSPIPSRRGRRKRKMRGPILPVKKNLRVKKAMSPLRAERNSPDFRRKLRSRDNRPNYHLFDYYNEIASSPNPSTTKITYNPPKLPMKDFATLPIGYQSTCDSDETSELSSTSSEQTSDVEGLNAYNNLGASSDIENAPSSQLHFGHIDEKTIRSTDPFANRENLDFNSIGGLEDIILQLKEMVMLPLLYPEVFLHLHITPPRGVLFHGPPGTGKTLMARVLAANCSTKNQKISFFLRKGSDCLSKWVGEAERQLRLLFEEARRVQPSIIFFDEIDGLAPIRSSKQEQTHSSIVSTLLALMDGLDTRGQVVVIGATNRPNDLDPALRRPGRFDREFYFPLPNKQARMKILEINSLHFSPKIPESYLLHLAESTSGYGGADLKALCTEAALNAVRRTFPQIYTSSDKFLIDLNEISVSICDFVVASEKIAVSTRRSDVKPNIPITDSHKILFKKSIEVITSKIRRLLKLDVYLPTVESLQKLPAEELMRQKEINSLKTTMSFRPRLLITDIYGYGCTYLSKVLFSMLDGIHVQSLDISELLMDTTTSPRSLLTKIFSEARKNAPSIIFINNVEKWPSLFSHSFLSMFLLLLDSISPLEPVMLLGFANTNQEKLSSTVRSWFPSHRSEYHDLSFPDYSSRYSFFHYLLKRISFLPIHQKSAEAASVDILPKVLPVSKTSDLTDKVNRRQRKNDKKIKNKIQVKLSSILEMLRSRYKKFKKPIIDLNDIYIDESNERVVKGKSKDNFEYFLSGNTVTRKKDNACFKMMNFEEIERRLWSGRYCTPKEFLRDIKMIKQDAILSGDVNLKHKAKEMFAHAELNVDELIDAKLLYDCCQVSKREKAYKQLKQKKLNNAKDAHEMQESKNEETFVRNDVAQEDNFIELSSNEVRNVSNDEHKHTLFHGQSLTHNNLIAVTPPSRTGVEHKEENKKYDNVNIQKTLAKCAEEFAEHTNFNKVELLDFVYSKLSSTIWENREEHDLLKIVRDVRQTFFRSLEDMGV
What is the function of this protein?
Probable ATPase which may play a role in nucleosome organization.
What are the official names of this protein?
ATPase with bromodomain protein abo2, ATPase family AAA domain-containing protein abo2, AAA-ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSN11_MOUSE
Sequence: MAHCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSGYLSILASSTFAASAYILIFVGGLVMTTGFLGFGAIIREQKSCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKWHLNSTLTEHYGQPRAAEITASVDRLQQDFKCCGSNSSADWQHSAYILSQEALGRQVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFVADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQQQFY
What are the official names of this protein?
Tetraspanin-11, Tspan-11.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LPLT_PECCP
Sequence: MSQQTEPATPLLSRSMNAVIIAQFFSAFGDNALLFATLALIKQLVYPDWSQPFLQMGFVAAYIILAPFVGQIADSFSKGQVMMFANTLKLAGALLICVGGNPFLGYTLVGVGAAAYSPAKYGILGEITRGDQLVKANGLMEASTIAAILTGSVAGGVLADWNIYGALSICAVAYGIALGANMLIPRLNAARPGQPWHPVQMASSFFSACRVLWRDGDARLSLVGTSMFWGAGVTLRFLLVLWVPHALGITDNATPTLLNAMVAVGIVVGAGAAAKLVTLDSVRRCLPAGFLIGVVVVIFTLQHNLMSAYSLLILLGALGGFFIVPLNALLQERGKASVGAGNAIAVQNLGENGAMLLMLGLYSLVVKLGVSVIAIGIGFGVLFALAIALLWVWLILAKRRDRSASAE
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPL_HUMAN
Sequence: MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG
What is the function of this protein?
Key enzyme in triglyceride metabolism.  Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (PubMed:8675619, PubMed:11342582, PubMed:27578112).  Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (PubMed:7592706, PubMed:12032167).  Mediates margination of triglyceride-rich lipoprotein particles in capillaries (PubMed:24726386).  Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (PubMed:11342582, PubMed:27811232).
What are the official names of this protein?
Lipoprotein lipase, LPL, Phospholipase A1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Secreted, extracellular space, extracellular matrix. Note=Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells (PubMed:27811232). Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity).