PharMolix/UniProtQA huggingface dataset:
Protein: CCSA_DRANE
Sequence: MIFSTLEHILTHISFSVVSTVLPIYFFTFLVNLDEIIGFFDSSDKGIVITFFGITGLLFTRWIYSGHFPLSNLYESLIFLSWAFSIIHMVSYFNKKQKNYLNAITAPSAIFIQGFATSGLLNKMPQSAILVPALQSQWLMMHVSMMILGYGALLCGSLLSIALLVITFRKVVPPFWNENIKTKNLLNELFYFDVYYIKERNSILLQQNSNFSFSKNYYRSQLIEQLDFWSFRIISLGFIFLTVGILSESVWANETWGSYWNWDPKETWAFITWTIFAIYLHIKTNRNVRGIHSPIVDAIGFLLIWICYFGVNLLGIGLHSYGSFTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MURD_BACFN
Sequence: MKRIVVLGAGESGAGAAVLAKVKGFDTFVSDMSAIKDKYKTLLDGHGIAWEEGRHTEEQILSADEVVKSPGIPNDAPLILRLREQGTPIISEIEFAGRYTDAKMICITGSNGKTTTTSLIYHIFKSAGLNVGLAGNIGKSLALQVAEEKHDYYVIELSSFQLDNMYNFRADIAVLMNITPDHLDRYDHCMQNYINAKFRITQNQTSEDAFIFWNDDPIIKRELDKHGIRAHLYPFSAIKEEGSIAYVEDHEVVITEPIAFNMEQEQLALTGQHNLYNSLAAGISANLAGITKEDIRKALSDFQGVEHRLEKVARVRGIDFINDSKATNVNSCWYALQSMTTKTVLILGGKDKGNDYTEIEELVREKCSALVYLGLHNEKLHEFFDRLGLPVAEVQTGMKDAVEAAYKLAKKGETVLLSPCCASFDLFKSYEDRGEQFKKYVREL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTC_EDWI9
Sequence: MLTLEVCCYSLACAEIAQAAGADRIELCASQQDGGITPSYGTLVGCRERVSVPVHPIIRPRSGDFCYSDSEFALMKCDLALVRDLGFPGAVIGLLDEEGHIDLRRMGELMALAGPMAVTFHRAFDMCANPLQALSQLTDLGIARILTSGQQQTAEAGLPLLRQLQQASRGPLIMAGAGVRLSNLHKFSGIGLQEVHTSAGHCVPSTMRYRKAGVSMSHAENDEFSHYCVDGGMVEAMKSALQMMETVGCSI
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_RANMC
Sequence: MTIALGRFTKDEKDLFDTMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ENO_TREPA
Sequence: MSDIACIEAREIIDSRGNPTVEVDVSLSDGSFGRACVPSGASTGEFEALEMRDGDKERYNGKGVLKAVGTVNTLIADTLEGMDALNQGEIDHAMRNLDGTDNKSKLGANAMLGVSMACARAAADFLGVPLYRYLGGVHTFRMPVPMANIINGGKHSDNKIDFQEFMVMPIGAASMREAVRMTAEVFHALKGLLAADGKATSVGDEGGFAPDLDNEQALEYIMKAIAKAGLAPRKDVCIALDCASSELFDEGDRRGYKFWKSNPGKLFTAQEMIDLYKKWIATYPIVSIEDPLDQNDWAGYVQLTKELGDKVQIVGDDFFVTNTGRLARGIKEGSCNSILIKLNQIGTVTETVDAVRMAQNAGYAAVISHRSGETEDAFIADLAVALETGQIKTGSMSRSDRVAKYNQLMRIEEELGAQARYYGAKTFERFGC
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MSRB_METPP
Sequence: MSSTDDKPRKVQKTEAEWRAQLDPMQFEVTRHGATERAFTGKYADHWQEGVYHCVGCNAPLFDSGTKFDAGCGWPSYFQPLRGEIIDRVVDRSHGMVRVEVRCQDCGAHLGHVFPDGPEPTGERYCINSASLGFEPRK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RL2_PSEE4
Sequence: MAIVKCKPTSPGRRFVVKVVNKELHKGAPHAPLIEKKSKSGGRNNNGRITTRHVGGGHKQHYRLVDFRRNDKDGIPATVERIEYDPNRTAHIALLCYADGERRYIIAPKGVSAGDQLIAGALAPIKAGNSLQLRNIPVGSTVHGIELKPGKGAQIARSAGASAQLIAREGVYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGFPTKGAKTRGNKRTDNMIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CHSE2_MYCTU
Sequence: MFIDLTPEQRQLQAEIRQYFSNLISPDERTEMEKDRHGPAYRAVIRRMGRDGRLGVGWPKEFGGLGFGPIEQQIFVNEAHRADVPLPAVTLQTVGPTLQAHGSELQKKKFLPAILAGEAHFAIGYTEPEAGTDLASLRTTAVRDGDHYIVNGQKVFTTGAHDADYIWLACRTDPNAAKHKGISILIVDTKDPGYSWTPIILADGAHHTNATYYNDVRVPVDMLVGKENDGWRLITTQLNNERVMLGPAGRFASIYDRVHAWASVPGGNGVTPIDHDDVKRALGEIRAIWRINELLNWQVASAGEDINMADAAATKVFGTERVQRAGRLAEEIVGKYGNPAEPDTAELLRWLDAQTKRNLVITFGGGVNEVMREMIAASGLKVPRVPR
What is the function of this protein?
Involved in the third cycle of side chain dehydrogenation in the beta-oxidation of cholesterol catabolism (PubMed:26161441).  Contributes partly to the virulence by increasing the efficiency of beta-oxidation (PubMed:22045806, PubMed:23560677).  Catalyzes the dehydrogenation of 2'-propanoyl-CoA ester side chains of 3-oxo-4-pregnene-20-carboxyl-CoA (3-OPC-CoA) to yield 3-oxo-4,17-pregnadiene-20-carboxyl-CoA (3-OPDC-CoA).  Also able to dehydrogenate steroyl-CoA such as 3-oxo-chol-4-en-24-oyl-CoA (3-OCO-CoA), 1beta-(2'-propanoyl-CoA)-3a-alpha-H- 7a-beta-methylhexahydro-4-indanone (indanone-CoA ester), hexahydroindanone and pregenenone (PubMed:22045806, PubMed:23560677).
What are the official names of this protein?
Acyl-CoA dehydrogenase FadE29, ACAD, 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase beta subunit, 3-oxo-4-pregnene-20-carboxyl-CoA dehydrogenase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: MT1_DROSI
Sequence: MPCPCGSGCKCASQATKGSCNCGSDCKCGGDKKSACGCSK
What is the function of this protein?
This protein binds cations of several transition elements.  It is thought to be involved in detoxification processes.
What are the official names of this protein?
Metallothionein-1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 5 family.
Protein: Y938_METJA
Sequence: MIIKVMVMLLIELTYAFIFVIIAVLIAYREKLGIEKKILYVSILALIQLFILGFVLLYIFSFGMVGAFLMIGVMITLASYLIMREINLKNKTKLFICLFITFLTTTIVSLAVLTIPKVVKFEPIYVIPLMGMVIGNTMNTIHLALDKIIDMVKSERDILWGYLALGATEIEALRPFIKNAVKSAVIPQMNRTKSVGVIFIPGAMVGMLLSGANPIYAAEIQIIIMWMILSSAVISGILICYLMYKEIIRA
What are the official names of this protein?
UPF0014 membrane protein MJ0938.
What is the protein family that this protein belongs to?
Belongs to the UPF0014 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL2_KORVE
Sequence: MAIKTYRPLTPTLRFQTKLVNEELTTDRPHKPLTKTKQRTGGRRNAGDITIWHRGGGHKRKLRLIDFKRDKSGVPATVATVEYDPNRSANIALLHYADGEKRYILHPVGLKVGQKVVSGPDADILVGNALPLRNIPAGTVVHNIELKPGKGAQMARSAGAQAQLVAKESDYALLKLPSGETRRVLVDCMATIGQVGNLDYENVAIGKAGRTRWMGVRPTNRGVVMNPVDHPHGGGEGKTSGGRHPVTPWGQPTRGYKTRNNKRTDKFIVTRRGKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TMCAL_LACPL
Sequence: MQAVGLITEYNPLHNGHRYHLRQAQQLTNADCVIVVMSGDWLQRGEPAILDKWTRAKLALENGADLVIELPVFFATQPAHLFARGGIELLSALDCTSVVFGAEHPELDFQRLATAIAARQGSFTHYNATFATQFNAALQAATGVTLTAANDMLSFCYYAANQTLAHPMQLLPIKRRQADHATTTIAADSRYASGTAVRQAALAQDWAALKPVVPADTFTALTTQRLQRWSDFWPFLQYQLLTVDVARSGQYDQMAEGLEYRMQAMAQHATTFDDFIHQVKSKRYTYTRLQRVATAALLQLTQAEVQKAQAHNYLRVLGFTPKGQAYLHQVKKQLPLPLYTKINQDLRQHALNLDYRAGRVYQLINGQSQDLYRQPWRLPVTIG
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_BRAHW
Sequence: MAKYVVAIDQGTTSSRAIVFDYDQNMVSVAQKEFTQIYPHEGWVEHNAAEIWATQFGVLQEAIQIAGVKPEEIAAIGITNQRETTVVWDKNTGEPIYNAIVWQCRRTAPICDELKKKGLDTYIRENTGLVVDAYFSGTKIKWILDNVPGAREKANKGELLFGTIDTWLVWKLTGGKVHVTDYTNASRTMIYNIKELKWDETILKELDIPMSMLPEVKDSSCIYGYAHINGKEVPISGIAGDQQSALFGQAGFNKGDTKNTYGTGSFILMNIGENFILSKNGLITTIAIGYNGKIEYALEGSVFIAGAVIQWVRDELRLLHDAKDTEYFATKVKDTNGVYLVPAFVGLGAPYWDMYARGCLVGITRGVNRSHIIRAAEEAIAYQSKDVIDAMVADSGVKLSSLKVDGGACRDNFLMQFQSDIINTKVLRPQITETTALGAAYLAGLAVGFWKDKDEITNRWKLEREFTPSLSEEERNKKYMGWKKAVERSRGWAL
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SYS_METBF
Sequence: MLDLKFVRSSPDIVRHALINRNMSTELIDSLLEYDIAWRKCLTEGDELKHKRNVVTREIAKLKKENKDTLSKIEEMQGINSRIKEIDDIIRDYKSKIHEIMLRIPNIPSSTTPVGKDENDNPVVRIVGEPRKFTFTPKPHWEIGEALDILDFEKGAKISGQGFTVYKGMGAKLERALVNFMLEVHARQGYLEVFPPVLINEKAMTGTGQLPKFKDDMYLCTDGYYLAPTAEVPVTNLFMDDYIEKLPVFLTAYTACFRREAGKHGQDTRGIIRQHQFNKVELVKFVKPETSYDELEKLTNDAEEILKLLKLPYRVVNLCTGDIGFSAAKTYDLEVWVPTQEKYREISSCSNFENFQARRANIRFRTPDGPQFVHTLNGSGLAVGRTVVAILENYQREDGSVEIPEVLRPYLGGAKEISNEVKT
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_ROSDO
Sequence: MAERDNNRRGNRRDRDEAPEFADRLVAINRVSKTVKGGKRFGFAALVVVGDQKGRVGFGKGKAKEVPEAIRKATEQAKRQMIRVQLREGRTLHHDMEGRHGAGKVVMRSAPEGTGIIAGGPMRAVFEMLGVKDVVSKSIGSQNPYNMIRATMDGLRKESSPRSVAQRRGKKVADILPKVDAAPAPAETAEA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: URK_BORHD
Sequence: MVKIIGIAGGSGSGKTTIVNKISEVIPEFVLISQDNYYKSVGDYEYEFLDVNFDHPDAFDNNLFYKQLKKIKENKLIHMPLYDFINHRRKDETVEIVPTPVVIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLERDMSKRGRTLESVIEQYLSTTRAGYYRFIEPTKEYADLIIPEGGHNDKALYVLSSFLRTLGKEGADFF
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPSN_HUMAN
Sequence: MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV
What is the function of this protein?
Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction.  It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.
What are the official names of this protein?
43 kDa receptor-associated protein of the synapse, RAPsyn, 43 kDa postsynaptic protein, Acetylcholine receptor-associated 43 kDa protein, RING finger protein 205.
What is the protein family that this protein belongs to?
Belongs to the RAPsyn family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Postsynaptic cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Cytoplasmic surface of postsynaptic membranes.
Protein: ATPL_SALSV
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCR5_LOPAT
Sequence: MDYQVSSPTYDIDYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLLFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYGA_BACLD
Sequence: MNIQEMILTLQKHWSNEGCVLLQSYDVEKGAGTMSPYTFLRSLGPEPWKVAYVEPSRRPADGRYGDNPNRLYQHHQFQVIIKPSPDNIQELYLDSLKALGIDPLEHDIRFVEDNWENPSLGCAGLGWEVWLDGMEITQFTYFQQVGGLECKPVSVEITYGIERLASYIQDKENVFDLEWTNGYTIKDLFKMAEYEHSVYTFETSDVDMLFELFATYEKEANRQMDQGLVHPAYDYVLKCSHTFNLLDAKGAISVTERTGYIARVRNLARKVAKTYYDEREKLGFPMLKEEEASHE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSY_ECOLI
Sequence: MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELETALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).  Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distributed between the membrane and the cytoplasm (PubMed:18281057, PubMed:8194520). Binding to the membrane probably occurs initially through phospholipid binding, which allows a strong membrane contact, followed by interaction with a membrane protein (PubMed:11353766). Targeting of FtsY to the membrane is essential for proper function (PubMed:9177162). The stability of this membrane contact may be regulated by cleavage of helix 1 (PubMed:19414018).
Protein: SSPK_BACVZ
Sequence: MVRNKAKGFPNQNNNKFEGEPRAKDDYASKRADGSINSHPQERMRASGRR
What are the official names of this protein?
Small, acid-soluble spore protein K, SASP K.
What is the protein family that this protein belongs to?
Belongs to the SspK family.
What are the subcellular locations of this protein?
Spore core.
Protein: RL31_RHOPT
Sequence: MKTEIHPDYHTITVVMTDGTEYQTRSTWGKEGDKLNLDIDPKSHPAWTGGTQQVLDRGGRVSRFQKKFSGFLKKD
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ADPRH_MOUSE
Sequence: MGGGLIERYVAAMVLSAAGDTLGYFNGKWEFIRDGETIHQQLAQMGDLEAIDVARWRVSDDTVMHLATAEALMEAGQSPDLPRLYSLLAKHYRDCMGDMDGRAPGGACMQNAMLLQPNRADGYRIPFNSHEGGCGAAMRAMCIGLRFPHPSQLDLLIQVSIESGRMTHHHPTGYLGSLASALFTAYAVNGKSPWQWGKGLMEVLPEAKKYITQSGYFVKENLQHWSYFEKEWEKYLELRGILDGNSAPVFPQPFGVKERDQFYIDVSYSGWGGSSGHDAPMIAYDALLAAGDSWKELAHRAFFHGGDSDSTAAIAGCWWGVMYGFKGVNPANYEKLEYRQRLEEAGRALYSLGSKEDPVLDP
What is the function of this protein?
Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.
What are the official names of this protein?
ADP-ribosylhydrolase ARH1, ADP-ribose-L-arginine cleaving enzyme, [Protein ADP-ribosylarginine] hydrolase, ADP-ribosylarginine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
Protein: UBIP1_HUMAN
Sequence: MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDGETEHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDAPTAYVNNSPSPAPTFTSPQQSTCSVPDSNSSSPNHQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCREQPSSTVLQGQQQAASSASENGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK
What is the function of this protein?
Functions as a transcriptional activator in a promoter context-dependent manner.  Modulates the placental expression of CYP11A1.  Involved in regulation of the alpha-globin gene in erythroid cells.  Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity).  Involved in regulation of the alpha-globin gene in erythroid cells.  Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box.  Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
What are the official names of this protein?
Upstream-binding protein 1, Transcription factor LBP-1.
What is the protein family that this protein belongs to?
Belongs to the grh/CP2 family. CP2 subfamily.
Protein: PUR9_BACCN
Sequence: MKKRALVSVSNKTGVVEFVKGLLEQGIEVISTGGTKKLLEENGLQVMGISEVTGFPEIMDGRVKTLHPNIHGGLLAVRDNEAHVAEMSELGIQLIDFVVVNLYPFKETIAKPDVTFADAIENIDIGGPTMIRSAAKNHKFVSVIVDPADYDVVLAELKEKGEVTDETKRKLAAKVFRHTAAYDALISNYLTEQMGEESPEILTVTFEKKQDLRYGENPHQKATFYKAPFAVASSVAYAEQLHGKELSYNNINDADAALSIVKEFTEPAVVAVKHMNPCGVGVGTDIHEAYTRAYEADPVSIFGGIIAANREIDKRVAEKLHEIFLEIIIAPSFSKEALEVLQSKKNLRLLTVNIEKTTSASKKLTSVQGGLLVQEEDTLALNEETIIIPTKREPTEQEWNDLKLAWKVVKHVKSNAIVLAKDNMTIGVGAGQMNRVGSAKIAISQAGSKAQGSALASDAFFPMPDTVEEAAKAGITAIIQPGGSIRDEDSIKKADEYGITMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MUTS_CHLL2
Sequence: MSAKGVSEKEHSPMMRQYLDVKDRYPDYLLLFRVGDFYETFFDDAREVAAALNIVLTRRSNEIPMAGFPHHASEGYIAKLVKKGYKVAVCDQVEDPAVAKGIVRREITDIITPGVTYSDSILDDRHNNYLCAIVFLRVGRQTVCGAAFIDVTTGEFRIAGLLPEDASVFLRSLHPAELLVSAADRERSETLRHALPAGTAFTVLDEWLFREEQAGEILARQFRTHSLKGFGIHDNPAGQVAAGVILHYLEETRQSSLQYITRITPLQSGDYMTLDLQTKRNLEIISSMQDGSINGSLLQVIDRTRNPMGARLLRQWLQRPLLRAADITMRLDAVDELKKMKPFRESVCCDLGQISDLERALARIATLRAIPREVRQLGSALAVIPLLKQSFQDTVSKRLCSIADALMPLPDLVAMIESAVDPEAGASMRDGGYIRKGYHQELDDLRQTASTAKERLLEIQQEERERTAIGSLKVQFNRVFGYYIEISKANRDKVPPYYEKKQTLVNAERFTIPALKEYEEKILNAEERSLVLEQQLFQALCCRIAGHAEVIQENAALIAEIDCLAAYAVCADEYGYCKPLIAEHTGLRILNGRHPVLERILPADEPYIANDALFDDRQKMLMITGPNMAGKSSYLRQTGLIVLLAQAGCFVPAEQAEIGVVDRIFTRVGASDNLASGESTFLVEMNEAADILNNATAKSLLLLDEIGRGTSTYDGLAIAWSMCEYIHRQIGARTLFATHYHELAELEGLLPGVVNYNASVLESGDRVIFLRKIVRGASDNSYGIEVARMSGMPSAVITRAKAILAGMEKRDIATPSSSGLSLQSMQISLFDEIDTRLRTAIEVIDIDRMTPLDALVELKKLQGLVRTGNII
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.