PharMolix/UniProtQA huggingface dataset:
Protein: OLF49_MOUSE
Sequence: MANSTTVTEFILLGLSDACELQVLIFLGFLLTYFLILLGNFLIIFITLVDRRLYTPMYYFLRNFAMLEIWFTSVIFPKMLTNIITGHKTISLLGCFLQAFLYFFLGTTEFFLLAVMSFDRYVAICNPLRYATIMSKRVCVQLVFCSWMSGLLLIIVPSSIVFQQPFCGPNIINHFFCDNFPLMELICADTSLVEFLGFVIANFSLLGTLAVTATCYGHILYTILHIPSAKERKKAFSTCSSHIIVVSLFYGSCIFMYVRSGKNGQGEDHNKVVALLNTVVTPTLNPFIYTLRNKQVKQVFREHVSKFQKFSQT
What is the function of this protein?
Odorant receptor.  Activated by (-)-citronellal and to a lesser extent by (+)-citronellal.  Not activated by carvone or limonene.
What are the official names of this protein?
Olfactory receptor 49, Olfactory receptor 118-1, Olfactory receptor I-C6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBY_CYAP4
Sequence: MDLDFRVLVVLLPVLLAGGWALKNILPAALRQVQSFFSK
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SCPB_STREM
Sequence: MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQKYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQPITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHLEELVDISSIAVEEQETTLF
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: HEPA_GAHVM
Sequence: MRQTISTMAASSKTNMMQIMRGCICYTTVYRIWTNKNRTEGLTALCYLLFRNTCGQYSAQYSTVNLSGKSMAKLWGLNPDMITDTMLAGMTNSASVTGLWPSCPSDQHMLWKALLTTTLAKLRHRLGYHAYYTPVTIYIDSQTGLVTACEPVSGERSIPRPGLLKTDGMISVEESCLISTAMKHAEGAPLAHIKLSALKRTRQIPEFDMRIEIQTKEERFLREYKKVNSPYKKFKCDNNSNTIFKVVDNTLVLDHLQPPVRALSLVPTSFDCLVTTPAEFSLVALLATYAKWHEKLYSCDNESTNILVPILMYIGPETNPRGEDVDYSCIIGFPGWPIVKSSTANQTAIKDAIDAYVDTDGLWPLAGPRTFHLLAPWSPENHPFPMIDTSHILSVHSTDIRHKAADEWTTGRITCILRDPTLIENAAIAKFDFSAFFATLYLGLFPTHSRLHDVVKARLKREKPWLKRPILEFGGLLKKLNEDVYQSIISIGNHISIEVEATASSLMFAPCTYIKDGMWGTFMDKSKNVPRPPMDDERDFNILRNACAESANNFAATIGLQFPDEILLDLRLEGIYTHAMSWNANCYWLWNKSNHHKDFVGFPNQPRFASYAKHGLSTLLEKICISNDTDESLQTVREKTHEVFEELLSIAFDHRSDVSFWSCPTELYDDTQYIAALGMKAAARFDTSGFNRETVQTVTADGKIVSVTCSLFEGEIILPAIDCIDYMKPILAAFSRLLINVLSSKWDNVNRDDFTFDIESYRFMFINNK
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase presumably elongates using dNTPs.  The primase-associated factor has no known catalytic activity in the complex and may serve to facilitate the formation of the replisome by directly interacting with the origin-binding protein and the polymerase.
What are the official names of this protein?
DNA helicase/primase complex-associated protein, HEPA, Primase-associated factor.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HEPA family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MTND2_VITVI
Sequence: MGSFKDDREEVLQAWYMDDSDEDQRLPHHRDPKEFVSLDQLAKLGVLSWRLDADNYETDEELKKIREARGYSYMDFCEVCPEKLPNYEEKIKNFFEEHLHTDEEIRYCVAGSGYFDVRDQNDSWIRVWLKKGGMIVLPAGIYHRFTLDSNNYIKAMRLFVGDPVWTPFNRPHDNLPARQEYLEAFGQKEAANHVVDAAA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase 2, Acireductone dioxygenase (Fe(2+)-requiring) 2, ARD' 2, Fe-ARD 2, Acireductone dioxygenase (Ni(2+)-requiring) 2, ARD 2, Ni-ARD 2.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DNLJ_ECOLI
Sequence: MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RNB_SHIDS
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRCHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARILRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE1_BOVIN
Sequence: MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPVYKVATKRDVDVQIDQEAYLPEEIAGGVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32764564).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32764564).
What are the official names of this protein?
V-type proton ATPase subunit E 1, V-ATPase subunit E 1, V-ATPase 31 kDa subunit, P31, Vacuolar proton pump subunit E 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
What are the subcellular locations of this protein?
Apical cell membrane. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: EPHA_MYCTU
Sequence: MGAPTERLVDTNGVRLRVVEAGEPGAPVVILAHGFPELAYSWRHQIPALADAGYHVLAPDQRGYGGSSRPEAIEAYDIHRLTADLVGLLDDVGAERAVWVGHDWGAVVVWNAPLLHADRVAAVAALSVPALPRAQVPPTQAFRSRFGENFFYILYFQEPGIADAELNGDPARTMRRMIGGLRPPGDQSAAMRMLAPGPDGFIDRLPEPAGLPAWISQEELDHYIGEFTRTGFTGGLNWYRNFDRNWETTADLAGKTISVPSLFIAGTADPVLTFTRTDRAAEVISGPYREVLIDGAGHWLQQERPGEVTAALLEFLTGLELR
What is the function of this protein?
Could be involved in detoxification of extraneous host-cell epoxides.  Catalyzes the hydrolysis of epoxide-containing substrates.
What are the official names of this protein?
Epoxide hydrolase A, EHB, Epoxide hydrolase EphA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
Protein: YWRD_BACSU
Sequence: MNKSVIGTKQMVVSPHYLASQAGNRILDKGGNAFDAAVAVSACLAVVYPHMTGLGGDSFWLTFHQETKAVKVYNGSGRSGKNVTRDVYKGKSAIPLRGIDSAITVPGMVDSWDAVLKEYGRLSLADVLEPARDYAQNGFPVSADQCRHTEKNIELLASTPYTADIFTRRGKAPVPGERFVQKELADSLNLIAEKGRSAFYEGDLAQRIVSHLQNNGSYMTIDDFKAHRGEWAAPVSSDYRGYSVYQAPPNSQGFTGLLTLNILENYDFTQIEHGSFEYYHVLVEALKKSFLDRDAVLTDPAFADIPLERLLDKRYAKQLAEEIGYLAIPAESRPVGSDTAYAAVIDADGNAVSFIQSLYFEFGSAVTAGDTGILLQNRGSFFSLDENHVNTLEPRKRTFHTLMPAMVCKGGKPKILYGTQGGEGQPQTQTAIITRMLDYGMHPQQAISEPRWVWGRTWGEEYEGLRVEGRFTDKTIQKLKDSGHLVEVVGDYDPLMGQAAAIKVDEEGFLQGGADPRGDGAAVGI
What is the function of this protein?
Overexpressed protein with an N-terminal His tag has been reported not to hydrolyze glutathione; it is not clear if the construct is processed to 2 subunits (PubMed:14762019).
What are the official names of this protein?
Glutathione hydrolase-like YwrD proenzyme, Putative gamma-glutamyltransferase YwrD.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
Protein: ISPH_FUSNN
Sequence: MEIIRAKHMGFCFGVLEAINVCNSLVEEKGRKYILGMLVHNKQVVEDMERKGFKLVTEDELLNDMDELKEDDIVVIRAHGTSKSVHEKLKERKVKVFDATCIFVNKIRQEIEIANENGYSILFMGDKNHPEVKGVISFADDIQIFESFEEAKKLKIDLDKTYLLSTQTTLNKKKFEEIKKYFKENYKNVVIFDKICGATAVRQKAVEDLAVKVEVMIIVGDTKSSNTKKLYEISKKLNDNSYLVENEEQLDLSIFRGKEVVGITAGASTPEETIMNIEKKVRGIYKMSNVNENQNEFSLMLEEFLPNQEKRVEGVIESMDQNFSYLDVPGERTAVRVRTDELKDYKVGDTVEVLITGLSEEDDDQEYITASRRKIEVEKNWEKIEDSFKNKTILDAKVTKKIKGGYLVEAFLYPGFLPNSLSEISDSEEKVNGKKIQVIVKDIKMDPKDKKNRKITYSVKDIRLAEQEKEFAGLAVGQIVDCVVTEVLDFGLAVDINTLKGFIHISEVSWKRLDKLSDNYKVGDKIKAVVVSLDEAKRNVKLSIKKLEEDPWATVANEFKVDDEIEGIVTKVLPYGAFVEIKPGVEGLVHISDFSWTKKKVNVADYVKEREKIKVRITDLHPEDRKLKLGIKQLVANPWETAEKDFAIDTVIKGKVVEVKPFGIFVEIADGIDAFVHSSDYNWVGEEIPKFEIGNEVELKITELDLNNKKIKGSLKALRKSPWEHAMEEYKVGTTVEKKIKTVADFGLFIELIKGIDGFIPTQFASKEFIKNIRDKFSEGDVVKAQVVEVNKETQKIKLSIKKIEIEEEKREEREQIEKYSTSSSEE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the IspH family.
Protein: FABH_STAA1
Sequence: MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD226_MOUSE
Sequence: MAYVTWLLAILHVHKALCEETLWDTTVRLSETMTLECVYPLTHNLTQVEWTKNTGTKTVSIAVYNPNHNMHIESNYLHRVHFLNSTVGFRNMSLSFYNASEADIGIYSCLFHAFPNGPWEKKIKVVWSDSFEIAAPSDSYLSAEPGQDVTLTCQLPRTWPVQQVIWEKVQPHQVDILASCNLSQETRYTSKYLRQTRSNCSQGSMKSILIIPNAMAADSGLYRCRSEAITGKNKSFVIRLIITDGGTNKHFILPIVGGLVSLLLVILIIIIFILYNRKRRRQVRIPLKEPRDKQSKVATNCRSPTSPIQSTDDEKEDIYVNYPTFSRRPKPRL
What is the function of this protein?
Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.  Cell surface receptor for NECTIN2.  Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG.  Competes with PVRIG for NECTIN2-binding.
What are the official names of this protein?
CD226 antigen, Platelet and T-cell activation antigen 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PHLB_MYCTO
Sequence: MGSEHPVDGMTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC
What is the function of this protein?
Involved in virulence (PubMed:12100560).  Induces cytotoxic effects on mouse macrophage cell lines, via direct or indirect enzymatic hydrolysis of cell membrane phospholipids (By similarity).  Hydrolyzes phosphatidylcholine (PubMed:12100560).
What are the official names of this protein?
Phospholipase C B, PLC-B.
What is the protein family that this protein belongs to?
Belongs to the bacterial phospholipase C family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Remains associated with the cell.
Protein: MURI_CLOBJ
Sequence: MSINDKPIGFFDSGVGGISVLKEAFKLLPKEDFLYYGDSKNAPYGTKKVEEVKALTSNATDFLMNKGIKALVVACNTATSVTINDLRENYDIPIIGIEPALKPAVELKKGGKIIIMATPMTLAEKKFANLMDLYKETEDIEPLPCPGLPELIEQGIVSGDIIYNYLKDKFSKYDNEKISSIVLGCTHYPFIEETLKEVTHNKACIIDGSFGTSRELKRQLKNSNMLREENRVGKVTIFNSREDKDIIDLSYKLFNMK
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: HRCA_MYCCT
Sequence: MLTKRQVKILQTIVEEFIKTNQPVGSKRILELLDIKISSATIRNESAILEHEGYLEKQHTSSGRTPSTKGYRYYVDNIMKLDSADYTRLKIYLNQLLDLRKYDIDKTINYASEIISELTKMTAVVIKKQNIKNIKLKKIELILLSEFLASVLFIFSDGDVQNKMFNLKDISLSDLKIAIKLFSDFLVDVKLDEIDQYLNDLKHQLSLSIKQYDYVLNTFINTILESKNEQKETHGMRYMLENPEFNDTNKLKNAVKLVEQLSPFDWFNIAYESNKNMNKIAIKIGNEIDQINDDISMIATELKIGNSSTVLTLVGPKRVDYNQVNQLMNLIIEIINAKEN
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SMD2_DICDI
Sequence: MSRMNDETMEDKPDDSNGPLSILMDSVNNNTQVLINVRNNKKLLGRVRAFDRHCNMVLENVKEIWTEVPKTAKGKKKAKPINKDRFISKMFLRGDSVILVLKNPLGAPPQAN
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
What are the official names of this protein?
Probable small nuclear ribonucleoprotein Sm D2, Sm-D2, snRNP core protein D2.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: DNAK_DECAR
Sequence: MGKIIGIDLGTTNSCVAIMEGGQPKVIENAEGARTTPSIIGYTEDGEILCGAPAKRQAVTNPKNTLYAVKRLIGRRFEEKEVQKDISLMPFKIVKADNGDAWVEARDKKIAPPQVSAEVLRKMKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGMDKTSKSDRKIAVYDLGGGTFDISIIEIANVDGETQFEVLATNGDTFLGGEDFDQRLIDYIIDEFKKESGVNLKADVLALQRLKEAAEKAKIELSSSQQTEVNLPYITADASGPKHLALKITRAKFESLVDELIERTMAPCVTALKDAGCKISDIDDIILVGGQSRMPKVQEKVKEIFGKEPRKDVNPDEAVAVGAAIQGGVLQGEVKDVLLLDVTPLSLGIETLGGIMTKLIQKNTTIPTKASQTFSTADDNQAAVTIHVLQGEREVASGNKSLGQFNLEGIPPAPRGTPQIEVIFDIDANGIMHVTAKDKATGKENKITIKANSGLSEAEIQAMVKDAELHAEEDKKAHELADARNQADGMVHMVKKSLTEYGDKLDASEKAAIEAAIKDVEDVLRDGDKETITAKTEALSAAAQKLGEKMYAQQQAEGAAAGATGQQAEAGEKTVEGDVVDAEFTEVNKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PB1F2_I71A1
Sequence: MEQEQDTPWTQSTEHINIQKKGSGQQTRRLGRPNLTQLMDHYLRIMSQVDMHKQTVSWKQWLSLKNPTQGSLKTRALKQWKLFNKQGWTD
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: APAG_PSEP1
Sequence: MSDPRYQIDVSVVTRYLKEQSDPENSRFAFAYTITVQNNGSLSAKLLSRHWLITNGDGEVEEVRGAGVVGQQPNIDPGQSHTYSSGAVISTRVGTMQGSYQMFAEDGKRFDAEIAPFRLAVPGALH
What are the official names of this protein?
Protein ApaG.
Protein: ILVD_CAMHC
Sequence: MRSDVIKKGYIRAPHRSLLRATGLKDDDFKKPFIGVCNSFAEIIPGHFFLNKFAKIIKDEIRKNGCVPFEFNCIGVDDGIAMGHDGMLYSLPSREIIANSVETMMNAHKLDALICIPNCDKIVPGMIMGALRVNVPTIFISGGPMAAGRGKNGEALDLNSTFEAVGAYEVKKINKKELHDIECAACPGAGSCSGMFTANSMNTLCEAMGIALKGNGTILAMTKNRKKLAKKAARRICEIALDDKFKIRNIINKKAVENAMVVDMAMGGSSNTILHMLAISREAGCALDIKELNEISKKTPHIAKIAPSKPEIHMQDVHNAGGINAIMNEVKDLLHLDNLTVTGETLGERIKGAKIKDEDVIHKVENAYSKVGGLAILFGNLAEQGCVIKAAGIIGSRKFSGKAICFNSQDEAIEGISGGKVKKGDVVVIRYEGPKGGPGMQEMLSPTSLIVGRGLGADVALITDGRFSGATRGLCIGHVSPEAAEGGMIGLLKDGDIIDIDVDNFSINVRLSEDEIAERKKEFKYGGKKVQSRWLRQYQKLVTNASNGAILEA
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: NCAP_QRFVE
Sequence: MEVDPAPSTAPKPTRKRVNNSGEEIGSGGKRALTGLSLTQKVAIHHAIALMVYHVVIDIFKCTIIDLITDVNIGVYAMNQIWSIHNYFRTKNNSGRSSIGAKIDNATDTYQFILHGRTITVNKEELKGVYKRCITTYFDWDKMNDWMGSVHTIMALWNLFGSRLSEVRIMPSANTISVEKDNRTTVVKDFNQYGIPAGMRHFATGADFKPTMKSALAQSMGPVTVLVQLSEAKDNQYAGKWVDALKRAFSHIPHIDQIAKFMLANKPAVLTKINGYLMAIAGYTGTREQKRIAFPPGTLAYLLHDLDKENKLHFNEDRCSKFDFSGAGAFRMYSHFLKVCKKNPLRMNIADPGKARQLLFHTMFGTHVEDFGILQSMTDVSDWLKRKDFEEEFKTLRASHARVEGNFYPIEMRYYSKVCSSLNTKMIGGGSAPVTNCQIFSGNRKRIVTEGLKSLGQQGVGAGLSALDKDSIEKLLREHLESIKAAFGDSFEAGTVKWRKFDGLTWDKEGDEVEMRPGEVGEIYWSN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What are the subcellular locations of this protein?
Virion.
Protein: DAPL1_XENTR
Sequence: MAKELKVQSPPQALKAGHLPAVKAGGMRVSKKQGNEENTAPEKNAKKTLQEKPSSVLNMTKMQAMNILAGELEKLSHDFPGEAAQIAHKKPRPTVEKIILPKRLYIIQQPRRC
What are the official names of this protein?
Death-associated protein-like 1.
Protein: DAPD_ACTP2
Sequence: MSLQAIIEAAFERRAEITPKTVDAETRAAIEEVIEGLDSGKYRVAEKIDGEWVTHQWLKKAVLLSFRINDNQIIDGAETKYYDKVALKFADYTEERFAQEGFRVVPSATVRKGAYISKNCVLMPSYVNIGAYVGEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIGDNCFIGARSEVVEGVIVEDGCVISMGVFIGQSTRIYDRETGEIHYGRVPAGSVVVSGSLPSKCGKYSLYCAVIVKKVDAKTLGKVGINELLRTIEE
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG18_CRYNB
Sequence: MSRLAKRHPDLLSCNFNQDYSCIAVGHKKGYTILNCDPFGKVHSNNDQGATGIVEMLFCTSLVALVGAAENQPSNSPRKLQIVNTKRQSTICELIFPTSVLAVKMNRKRLIVVLENEIYIYDISTMKLLHTIETGPNPNAVCALSSSSERSYLAYPSPVPSASSTPLSSSAIPAPPPAPTTGDVLLFDTISLTALNVIQAHKTPIAALALNSTGTMLATASDKGTVVRVFSVPDAKKLWQFRRGSSSARIFSINFNLMSTLLAVSSDTSTIHIYRLASSRKGGKDADDASTEEARSPTPSETPLASSPPLAGGKLDSHSAASSLRRRSYHLGKSFVGGVGGYLPKSVSEMWEPQRDFAFIKLRGNHGRTVVAMSATVPQVMVISSEGLFQAYNIDLENGGECSLMKEFALLGSEDFGNGSNGI
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.