PharMolix/UniProtQA huggingface dataset:
Protein: ENO_NITEC
Sequence: MSAIVDVIAREIIDSRGNPTIEADVLLESGVLGRASVPSGASVGTREAVELRDGDTQRYYGKGVLKAVENVNGEISEEIMGLDATEQCFIDKTLIELDGSENKSRLGANAILAVSLAVAKAAAEESSLPLYRYLGGTNSKWLPVPMMNLINGGVHANNRLDMQEFMIIPLGLPSLREAVRCGAEVFGKLRTLLHKKNLPTTVGDEGGFAPGFAHNEEALGLIVQAIDEAGYQPGSEVAIGVDCASSEFFRDGKYHLAVDGLSLTSAQFIDYLASWVEKYPIISIEDGISEQDWDGWKLLTERLGQTVQLVGDDIFATNTKILKKGINRNIANSILIKINQIGTLTETLNAIEMAKCAGYTAVVSHRSGETEDTMIADIAVGTNALQIKTGSLSRSDRLAKYNQLLRIEEDLGDVAQYAGRSAFYQLKP
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRMD_SHIDS
Sequence: MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP2_ROTPC
Sequence: MISRNRRRNTQQKDAEKEKQTENVEEKEIKEAKEQVKDEKQVITEENVDSPKDVKEQSNTVNLQKNDLVKEVINIQNQTLNTIVAENKVEIEEVVKKYIPSYSTDKLIVKNYRNSRIKCQTYNKLFRLLHVKSYLYDVNGEKKLSTRWYWKLLKDDLPAGDYSVRQFFLSLYLNVLDEMPDYVMLRDMAVDNPYSAEAGKIVDEKSKEILVEIYQDQMTEGYIRRYMSDLRHRISGETNTAKYPAILHPVDEELNKYFLEHQLIQPLTTRNIAELIPTQLYHDPNYVFNIDAAFLTNSRFVPPYLTQDRIGLHDGFESIWDAKTHADYVSARRFVPDLTELVDAEKQMKEMLQCKLNHNSWQELVHGRNEAFKFIIGTVLSTRTIAVEFITSNYMSLASCMYLMTIMPSEIFLRESLVAMQLAVINTLIYPALGLAQMHYQAGEIRRLELAEMQVANRPIRQWLHHCNTLQFGRQVTEGVTHLRFTNDIMTGRIVNLFSTMLVALSSQPFATYPLDYKRSVQRALQLLSNRTAQIADLTRLIVYNYTTLSACIVMNMHLVGTLTVERIQATALTSLIMLISNKTVIPEPSSLFSYFSSNINFLTNYNEQIDNVVAEIMAAYRLDLYQQKMLMLVTRFVSRLYIFDAPKIPPDQMYRLRNRLRNIPVERRRADVFRIIMNNRDLIEKTSERICQGVLLSYSPMPLTYVEDVGLTNVVNDTNGFQIINIEEIEKTGDYSAITNALLRDTPIILKGAIPYVTNSSVIDVLSKIDTTVFASIVKDRDISKLKPIKFTINSDSSEYYLVHNNKWTPTTTTAVYKARSQQFNIQHSVSMLESNLFFVVYNDLFKYIKTTTVLPINAVSYDGARIMQET
What is the function of this protein?
Inner capsid protein that self-assembles to form an icosahedral capsid with a T=2 symmetry, which consists of 120 copies of VP2, with channels at each of its five-fold vertices.  This capsid constitutes the innermost concentric layer of the viral mature particle.  It encapsidates the polymerase VP1, the capping enzyme VP3 and the genomic dsRNA, thereby defining the core.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels formed by VP2 N-termini.  VP2 is required for the replicase activity of VP1 polymerase.  Probably recruits a copy of a VP1-VP3 complex, potentially along with a segment of plus-strand RNA, as a decamer of VP2 assembles.  May activate the autoinhibited VP1/RNA complex to coordinate packaging and genome replication.
What are the official names of this protein?
Inner capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP2 family.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid protein. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: PABP5_PANTR
Sequence: MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARRRC
What is the function of this protein?
Binds the poly(A) tail of mRNA.  May be involved in cytoplasmic regulatory processes of mRNA metabolism.  Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein 5, PABP-5, Poly(A)-binding protein 5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_SHEEP
Sequence: MVLSAADKSNVKAAWGKVGGNAGAYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGEKVAAALTKAVGHLDDLPGTLSDLSDLHAHKLRVDPVNFKLLSHSLLVTLACHLPNDFTPAVHASLDKFLANVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1/2, Alpha-1/2-globin, Hemoglobin alpha-1/2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RTCB_MICPC
Sequence: MAPRRTYQQEMAFLSRVSANQWIVNEGFVPNMRVPGTFYVNKHLETLMFEELQQHVDSGGHGGFLPAVKQLANVACLPGIVGKSIAMPDVHSGYGFCIGNVAAFDMSDPAAVVSPGGVGFDINCGVRVVRTNLMESDVADVKEKLAQALFDHIPVGVGSQGIIPTSAAGLESALEMGMDWSLREGYAWAEDKEHCEEYGRMLTADPNKVSARAKKRGLPQMGTLGAGNHYAEIQVVDEIFDAHAAEKMGVDAVGQVMVMIHSGSRGLGHQVATDALTEMERAMARDGIETNDRQLACARINSTEGQNYLSAMSCAANYAWVNRSSMTFLCRQAFAKMFDSTPDDLDMHVVYDVSHNIAKIEEHMVDGKLKTLLVHRKGSTRAFPPHHPLIPVDYQYTGQPVMIGGTMGTCSYILTGTQKGMDETFGSTCHGAGRARSRNNSRNKLDYAEVLENLKTKGISIRVASPKLVMEEAPESYKDVTEVVNTCHDAGISKKAVKLRPIAVVKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: NRDI_YERP3
Sequence: MNPLVYFSSSSENSHRFVEKLQLPAIRIPIAGAREKLRVEQPYILLVPSYGGGSPVGAVPIQVIRFLNDVHNRSLIRGVIAAGNTNFGDAYCLAGDIISHKCQVPYLYRFELLGTAEDVANVRKGVTEFWQRQN
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: CCLOP_MEDTR
Sequence: MEGRGFSGLYKNSSEELFLKTVMESPIGMPVPTMEMLGFKTVSQSFRTDSEELFKRWLTNDQEGYNSSSMGLNSRLSKRISTEIANMSNQQHIGVASEGRNNDKSCLQNNFLANDVSSDFNFPIRDPVDRELQSSNLFLAKAWFITDQRMTRSRSSELRRRYTEMQNSQAPQGLDSMFMVPEHDTNTIKEELANFNGFDYLSMCELPSQKGTFMSPSNSSSSTFNTHQLVDVDKVSSCVSMLKGTLQRKKLECQVEKEAAEDGLNEIFCIREPLFQSAFNEEESWNQQKLVNVQGDFTDQVNDPGVMQTLEGTTNFVLDGFANQTNQIQGRTASGEPSQSESSAAAPVISSGLDACEGPSNSNQTLGDSSWKQVGESTQNKVRGVREQIMDNLKDDRKRKSLERYGSVTSAVSDGKMDNTKKRRVERSRKMAEAKERNLTPTIPSDMQAILKRCENLEKEVRSLKLNLSFMNRKDSEQTKQIEDLQKQNEDLADEKERLLEEIERILSETGKI
What is the function of this protein?
Involved symbiotic signaling.  Required for root infection by symbiotic rhizobia, infection thread (IT) formation, and nodule development.  Required for proper induction of early nodulin gene expression.  Probably not involved in nodule organogenesis.  Involved in arbuscular mycorrhizal (AM) symbiosis.  Required for fungal infection of the outer cortical cell layers, and for arbuscule development during the AM symbiosis.  Acts downstream of CCAMK (PubMed:21692638).  Required for symbiosome formation (i. e.  the release of the bacteria from the ITs) and subsequent symbiosome development.  Required for the expression of the nodule-specific RPG gene, which controls proper IT growth and is essential for symbiosome formation (PubMed:21787150).  Acts upstream of ERN1, a transcriptional regulator required for nodulation (PubMed:17449807).
What are the official names of this protein?
Protein CYCLOPS, MtCYCLOPS, DMI3-interacting protein IPD3, Interacting protein of DMI3, MtIPD3, MtSYM1.
What is the protein family that this protein belongs to?
Belongs to the CYCLOPS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NHAB_ECO8A
Sequence: MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKVREVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSLTGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLFYIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMGWIATL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYT_FRATN
Sequence: MINIRFPDGSIREFEAGVNSLDVAKSISPSLAKATVAAYIDDQLKDAKDAINSNCELRLITVKDPEGLEILRHSCAHLLAHAVKELYPSTEVTIGPVVDNGFYYDFSFKESIGEADLPTIEKKMKELAKKSAPVSYRVVPKAEAIEFFKAQGENYKVEIIDSIADEQVKIYTQDNFSDLCRGPHIPNTSVLKAFKLTKLAGAYWRGNSDNEMLTRIYGTCWATKEDLEQYLNMLEEAEKRDHRKIGKVLDLFHFQEDSPGIAFWHDNGVRIWRQVEDYMRASNNKYGCSEIRTPLIADFSLWQKSGHASKYAENMFATKSENRDFAIRPMNCPTCVQVYNTKLHSYRDLPIRMAEFGIVHRNEPSGSLHGLLRVRSFTQDDGHIFCTPEQVEEEVILMVQQCFEVYKDFGFNDFAVKIALRPENRIGDDETWDKSEQMLKNALDANNVSYELLPGEGAFYGPKIEFHLKDAIGRSWQCGTIQLDFSMPQRLGATYIDKNGEKQVPVMLHRAIVGSLERFIGMLIEHYAGNLPLWLAPVQVAVMGISNNQDDYCKEVFTMLEKNGIRAKLDLRNEKIGFKIREHTLLRVPYLVILGKNEQEQKIITIRKHSGEDLGQMSVDDFCAFLDKQIQAKE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_PARDP
Sequence: MKFFVDTADVAAIRELNDLGMVDGVTTNPSLILKSGRDILEVTKEICDIVEGPVSAEVVASKAGDMIREGEHLVKIAPNITVKVPLTWDGLRACKVLSSQGHKVNVTLCFSAAQAILAAKAGATFISPFIGRLDDINFDGMELIAQIREIYDNYDFQTQILAASIRSVNHITDAARIGADVITAPPAVIKAMANHVLTDKGLEQFNADWAKTGQKIV
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAQD_SCHPO
Sequence: MRLKVSCTEFPIQQWVETSSLELVDSVNCVADLCHAIWMFNGGCADWRLQILKEGFTVPMTGIISQYLKTDDHIKIVKEIYPPNLPVLPFRVYTTQNTSVESELVEWEDVEMEA
What are the official names of this protein?
Uncharacterized protein C18G6.13.
Protein: SEPF_BACC4
Sequence: MSWSKVKYFFFDTPEEKEAAQYGYEKEQTDMKKQQDPPEQQDVTFPKAQPKQNVVSIETAKQSSKVVLLEPRTYSEAQGIADHLKGRRAVVINLQRMSTDQAVRIVDFLSGTVYAIGGDIQKIGPKTFMCTPENVDIVGAISELFGEEEETNIKRW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: PYRD_HELAH
Sequence: MLYSLFKKYLFRLDAEEVHEKVCKILKILSRSPFFCNLIHAQFGYTNPKLENEILGLHFPNPLGLAAGFDKNASMIRALTAFGFGYLEAGTLTNTAQSGNEKPRLFRHIEEESLQNAMGFNNYGAVLGVRAFERFAPYKTPIGINLGKNKHIEQDNALEDYKAVLIKCLNIGDYYTFNLSSPNTPNLRDLQNKAFVSELFCMAKEMTKKPLFLKIAPDLEIDAMLEITNSAIEAGANGIIATNTTIDKSLVFAPKETGGLSGKCLTQKSREIFKELAKAFFNKTILVSVGGISDAKEAYERIKMGASLLQIYSAFIYNGPNLCQNILKDLVKLLQKDGFLSVKEVIGADLR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KAD_RHOCS
Sequence: MNLILLGPPGAGKGTQAQRLERTRGMVQLSTGDMLRALVRSGSPLGQRADAIMKAGQLVPDEVMIEMISDRIEQPDCAKGFILDGFPRTVVQAEALDRMLAEKGLRLDHVIEMVVDDAALTERITGRFTCAKCGTGYHDTFKRPAQDGVCDVCGSTEFTRRADDNAETVGKRLEAYHRQTAPILPYYADRGVLKKVDGMADIAEVARQIEAIIAG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2577_MYCTU
Sequence: MGADLKQPQDADSPPKGVSRRRFLTTGAAAVVGTGVGAGGTALLSSHPRGPAVWYQRGRSGAPPVGGLHLQFGRNASTEMVVSWHTTDTVGNPRVMLGTPTSGFGSVVVAETRSYRDAKSNTEVRVNHAHLTNLTPDTDYVYAAVHDGTTPELGTARTAPSGRKPLRFTSFGDQSTPALGRLADGRYVSDNIGSPFAGDITIAIERIAPLFNLINGDLCYANLAQDRIRTWSDWFDNNTRSARYRPWMPAAGNHENEVGNGPIGYDAYQTYFAVPDSGSSPQLRGLWYSFTAGSVRVISLHNDDVCYQDGGNSYVRGYSGGEQRRWLQAELANARRDSEIDWVVVCMHQTAISTADDNNGADLGIRQEWLPLFDQYQVDLVVCGHEHHYERSHPLRGALGTDTRTPIPVDTRSDLIDSTRGTVHLVIGGGGTSKPTNALLFPQPRCQVITGVGDFDPAIRRKPSIFVLEDAPWSAFRDRDNPYGFVAFDVDPGQPGGTTSIKATYYAVTGPFGGLTVIDQFTLTKPRGG
What are the official names of this protein?
Uncharacterized protein Rv2577.
Protein: RL22_SHIF8
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVQVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MSRA_STAEP
Sequence: MEQYTIKFNQINHKLTDLRSLNIDHLYAYQFEKIALIGGNGTGKTTLLNMIAQKTKPESGTVETNGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMSGGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLNNILKYYYGTLIIVSHDRALIDQIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRKYEQYISEKQRLSQASKAKRNQAQQMAQASSKQKNKSIAPDRLSASKEKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYHEFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTLLEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGLNEALERSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGIILFTSHDTRFVKHVSDKKWELTGQSIHDIT
What is the function of this protein?
Confers resistance to 14-membered ring macrolides (like erythromycin) and to B streptogramins, by acting as an ATP-dependent efflux pump.
What are the official names of this protein?
Erythromycin resistance ATP-binding protein MsrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: GD_DROME
Sequence: MRLHLAAILILCIEHVTKAVAQGMPISPCPKVFQYRFDGSEWFGLMAVRSPDGHQPLHIRVTLSMRGKPTTYTQNYLGEIELLTRGKFTHNAPVLYKIRFPKHHFPPKLLLMSANNHVICFGSGEHSIFMTQIQLEHIRKLSFIPDKKSSLLLDPEEEEVRKTDDKPPSTPHIQFKKKPFAQAPKEICGRIDRDLDFHLSQRTESLHVAIGEPKSSDGITSPVFVDDDEDDVLEHQFVDESEAEAIESDSADSLPSITRGSWPWLAAIYVNNLTSLDFQCGGSLVSARVVISSAHCFKLFNKRYTSNEVLVFLGRHNLKNWNEEGSLAAPVDGIYIHPDFNSQLSSYDADIAVIILKDEVRFNTFIRPACLWSGSSKTEYIVGERGIVIGWSFDRTNRTRDQKLSSELPGKKSTDASAPKVVKAPIVGNAECFRANAHFRSLSSNRTFCAGIQAEERDTHQSGASIYTGISGAGLFIRRNNRWMLRGTVSAALPAVETPDAESSHKLCCKNQYIIYADVAKFLDWITAFVI
What is the function of this protein?
Component of the extracellular signaling pathway that establishes the dorsal-ventral pathway of the embryo (PubMed:9618496, PubMed:9477324, PubMed:12493753).  Three proteases; ndl, gd and snk process easter to create active easter (PubMed:9477324).  Active easter defines cell identities along the dorsal-ventral continuum by activating the spz ligand for the Tl receptor in the ventral region of the embryo (PubMed:9477324).
What are the official names of this protein?
Serine protease gd, Protein gastrulation defective.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_PROMS
Sequence: MNFNSLRKEITSNNASVKELVNDFFVKIDHKDSKINSYICTTKDNAIAQAEDIDKLIQNNEKLPPLAGMPIAIKDNICTKGVATTCASNMLKNFVAPYESTASSKLWSSGGICLGKTNLDEFAMGSSTETSVFGVTSNPWDINRVPGGSSGGSAASVAAGFCAAAIGSDTGGSIRQPASFCGVVGLKPTYGRVSRWGLVAFASSLDQIGPITNTVSDAAEILHSISGKDPFDSTCLDKPVPNYLTDLNKSIKGLKIGIIKECFEHPGLNPEVKESVLSGVDRFQALGAEIIEVECPRFNDGIATYYVIAPSEASANLARYDGVKYGYRSNEGSNLIDMTSKSRAEGFGDEVQRRILIGTYALSAGYSDAYYKKAQKVRTLIRKDFDNAFKKVDVLLTPTCPTTAFLKGDFVNDPLSMYLSDLLTVPANLAGLPAISIPCGFDTKGLPIGLQLIGNVLEEDRILNAANIFEIDAHVIKKRPLF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: APT_PSEPF
Sequence: MVFDSFDIKSLIRPVIDFPKPGVIFRDITPLFQSPKALRLVMDSFAHRYVEADFTHIGAMDARGFLIGSVLAYQLNKPLVLFRKQGKLPADVLAEGYATEYGEAFLEVHADSLCEGDSVVMFDDLIATGGTLIAAANLIRRMGARVHEAAAIIDLPELGGSQRLEDMGIPTFCLTQFALTDK
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_HYDCU
Sequence: MTTTLWPQVLKQLEAVLNDQQFLTWIRPLEAVEEDNTLRLIAPSGFILDWVNKKLLSQIKQAVYLVAPVNTPEVTLEVGEYAIESFNEPENTSVPQPLRETKAEREAAEKAASSTSKKKSDSPPKKTIKHNLNTNFTFDTFVEGKANQLAAAAARQVADNPGGSYNPFFIYGGVGLGKTHLMHAIGNELMRRDPNARVVYLHSERFVADMVNALRHNKIDEFKRFYRSLDALLIDDIQFFAKKEQSQEEFFHTFNTLLEGNKQVILTSDRFPKEVDGLEDRLKSRFGWGLTIAVEPPEFEMRVAILMKKAAEFGFLLPDEVAFFIAKRLRGNVRDLEGALKRVGAFAQFTQQLVTVDLAKDALKDLLALQQKMVTLENIQKTVADYYKIRVADLLSKRRTRNIARPRQMSMAISKELTSHSLPEIGDAFGGRDHTTVLHAVRKINELKETDHRIEEDFNSLIRIITN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCB2_CULQU
Sequence: MVVRDYNTELTYIERISTNSFRIKKGFQPNMNVEGIFYANSRLEKLMFDELRNSCRPGMTGGFLPGVKQIANVAALPGIVGRSVGLPDIHSGYGFAIGNMAAFDMSDPTSIVSPGGVGFDINCGVRLLRTNLFEKDVKPVQEQLAQSLFDHIPVGVGSKGIIPMNAHDLEEALEMGMDWSLREGYVWAEDKEHCEEYGRMLTADPSKVSMRAKKRGLPQLGTLGAGNHYAEIQVVEEIYDKYAASKMGIEELGQICVMIHSGSRGFGHQVATDALVEMEKAMKRDKIETNDRQLACARINSVEGQNYLKAMSAAANFAWVNRSSMTFLTRQAFAKQFNTTPDDLDMHVIYDVSHNVAKIEEHIVDGRPKQLLVHRKGSTRAFPPHHPLIPVDYQLTGQPVLVGGSMGTCSFVLTGTEKGMAETFGSTCHGAGRSLSRAKSRRNLDYRTSCGIWRRREFPSGWRRRSWSRRKHPIRTRTCVMWCRPVTTWASVPSASSCGRLR
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog 2, 3'-phosphate/5'-hydroxy nucleic acid ligase 2.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: SEC13_LODEL
Sequence: MVTIGNAHEDLIHDAVLDYYGKRLATCSSDKTIKIYDIEGTENYKLTATLTGHEGPIWQVAWAHPKFGSILASCSYDGKVLIWKEQQDTQQWSIIAEHTIHQASVNSVSWAPHELGAVLLCTSSDGKVSVVDFNDDGTTSHVIFDAHAIGVNSASWAPFTAASSTSSKDANTLKQHRRFVTCGSDNLVKIWKYDTALETYAEEAKLEGHTDWVRDVAWSPSNLVRPYIATASQDCTVLIWTQDKDGKWQSQPLTEEKFPDVCWRCSWSLSGNILAVSGGDNKVTLWKENLQGKWESAGEVELIK
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: PHAD_RHIME
Sequence: MTDWLDHLLILPILLPLAVAAVLIPINERDRTLKGAIGFASTLVVFILSMILMRLAAAGTGSLPGSGVYQLGNWPAPFGIVLVLDRLSALMLCLTSGLALAAQAYSMARWHTAGHHFHSLFQLLVAGLNGAFLTGDLFNLFVFFEMMLAASYGLLLHGSGPLRVKAGLHYIAVNLAASALFLIGVSLIYGAAGTLNMADLATKLAALEPRSRTLVEMGSAILGVAFLVKAGMWPLSFWLPTAYAAATPPVAGVFAVLTKVGIYVIIRLHLLVFGTAAGASSGFGQEWLVTGGMLTIAFGGIGVLASQAMGRLAGYSVLVSSGTLLAAVGLGHDGMLAGALFYLVSSTLTIGAFFLLIELVERGRDAGADVLAVTMEAYGDFDEDEEEEEVGAAIPGTMAVLGLCFCLCALLLAGLPPLSGFIAKFALISGLFDMPAAELATAMSAADWTYVTLLILSGLAAMIAMNRIGIRTFWASIEGTIPRVVVIEITPVVVLLGACIFLSLQAGPAMRYMQATADDLLAPLTHSERVLSAPRAGSQ
What is the function of this protein?
Part of a K(+) efflux system which is required for the adaptation of R. meliloti to alkaline pH as well as for the infection process during symbiotic nodule development.
What are the official names of this protein?
Probable K(+)/H(+) antiporter subunit D, pH adaptation potassium efflux system protein D, Pha system subunit D.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.