PharMolix/UniProtQA huggingface dataset:
Protein: MRE11_SULAC
Sequence: MQLLHISDTHLGKRQYNLESREKDVYDTFTQLIDIAINEHVKAVIHTGDLFDVNNPPNRAKLHAIKELKRLKDHNIPFICIAGDHDSPKRKEEIYPQRILEEFNLIKILQKIDNRVKLENVEVYGISHISNVSVNDLKEQLSKVKPETRKSILMLHQGIRTYLPYQGAWQIELSDLPKGFSLYAVGHLHSRRKDYLDGGALIEIAGSPDIMREEEIEDYQKSKKGATLIDMSGDLPSINYINVNIRDQLVLDINVDKIEQSIESVIQKLKENVKNDKKPILHIELEGTVPIRKDVLMTKLQALRDYVEHYRIYKNNIVSIKEENLKTKLKTTYSSLNDIIADYLKGIGYTDEETKIIIDIINEEDEKKVEELLKKFAGVEDK
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity (By similarity).  Recruited immediately to chromosomal DNA after gamma irradiation, and remains DNA bound in the course of DNA repair (PubMed:18294364).
What are the official names of this protein?
DNA double-strand break repair protein Mre11.
What is the protein family that this protein belongs to?
Belongs to the MRE11/RAD32 family.
Protein: TRPF_STRZT
Sequence: MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAELAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQVDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQHFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RL27_LISW6
Sequence: MLKFDIQHFAHKKGGGSTSNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGTNVGRGGDDTLFAKTDGVVRFERMGRDKKKVSVYPEVQEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: 1433T_BOVIN
Sequence: MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Negatively regulates the kinase activity of PDPK1 (By similarity).
What are the official names of this protein?
14-3-3 protein theta.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPN_BACC7
Sequence: MGNPKKNSKDFAPNHIGTQSKKAGGNKGKQMQDQTGKQPIVDNG
What are the official names of this protein?
Small, acid-soluble spore protein N, SASP N.
What is the protein family that this protein belongs to?
Belongs to the SspN family.
What are the subcellular locations of this protein?
Spore core.
Protein: ISPG_HELPH
Sequence: MLENRVKTKQIFIGGVAIGGDAPISTQSMTFSKTADIESTKNQIDRLKLAGADLVRVAVSNEKDALALKELKKVSPLPLIADIHFHYKFALIAAQSVDAIRINPGNIGSKDKIKAVVDACKEKNIPIRIGVNAGSLEKQFDQKYGPTPKGMVESALYNAKLLEDLDFTDFKISLKASDVMRTIEAYRMLRPLVIYPFHLGVTEAGNLFSSSIKSAMALGGLLMEGIGDTMRVSITGELENEIKVARAILRHSGRLKEGINWISCPTCGRIEANLVDMASKVEKRLSHIKTPLDISVMGCVVNALGEAKHADMAIAFGNRSGLIIKEGKVIHKLAEKDLFETFVIEVENLAKEREKSLKD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GARL_ECOL5
Sequence: MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: NODD3_RHILO
Sequence: MRFKGLDLNLLVVLDALLTARNLTAAASSINLSQPAMSAAVARLRNYFNDELFTMSGRERVLTPRAETLAPAVRGALLHIQCSIISWDPFNPAQSDRRFRIILSDFATLVFFEKVVERVAREAPAVSFELRPLDNDPDELLRRGDVDFVILPEFFMSSAHPRAALFDETFVCVGCPTNKQLPRQLTFERYVSMKHIAFRVGGAQMPSIEEQFLLEHGLKRRVEIVVQAFSMIPPMVSGTARIATMPFRLVQHFKKTFPLRIIELPRPLPTFTEAVQWPTLHNSDPASIWMRQIMLQEASRM
What is the function of this protein?
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D 3.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RL322_LISMO
Sequence: MAVPFRRTSKAKKRKRRTHVKLQLPGMNECSNCGEYRLSHHVCPECGQYDGKDVANS
What are the official names of this protein?
50S ribosomal protein L32-2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RRAAH_THISH
Sequence: MEPAAYGLTATADLCDQHGEAAGVCETHFGDYGGITAFSGEIVTVRCFEDNVLVRQTLEAEGRGKVLVVDGGGSLRCALFGDMLAQTALDNGWAGVIVNGCIRDVAVIVTLPIGVKALGTHPRKSEKRGEGAVNVPVSFGAITFRPGERVFADEDGVVVLK
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: RL14_LEPIN
Sequence: MIQQETLLQVADNSGIKKVMCIKVLGGSKKRYASVGDEIIVAVKDAQPAFGLKDSTGKKVHNKAVQRAVVVRTTKEIRRPDGSYIRFDDNACAIIDDKGNPKGTRIFGPVARELRDKKYAKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: KCNJ2_BOVIN
Sequence: MGSVRTNRYSIVSSEEDGMKLATLAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKESKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPVAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDIDLHNQASVPLEPRPLRRESEI
What is the function of this protein?
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by extracellular barium and cesium (By similarity).
What are the official names of this protein?
Inward rectifier potassium channel 2, BIK, Inward rectifier K(+) channel Kir2.1, IRK-1, Potassium channel, inwardly rectifying subfamily J member 2.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Membrane; Lipid-anchor.
Protein: RL6_SYNJB
Sequence: MSRIGRRPIALPAKVEIQIDGQHIAVKGPKGQLSRSLPPLITVQQNAQMLTVSRLNDSRPARQLHGLCRTLVANMVDGVSKGFERRLELVGVGYRAAIQGSKLVLNVGYSHPVEIPFPPGIQIAVEGNNIIVVSGTDKELVGNTAARIRAVRPPEPYKGKGIRYLGEQVRRKAGKSGKAKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CRYAB_PONAB
Sequence: MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
What is the function of this protein?
May contribute to the transparency and refractive index of the lens.  Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.  In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome (By similarity).
What are the official names of this protein?
Alpha-crystallin B chain, Alpha(B)-crystallin.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Lysosome. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. Localizes at the Z-bands and the intercalated disk in cardiomyocytes. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: TSAD_AGRFC
Sequence: MPPFLRILGIETSCDETAASIVVRHADGRGEIVSDVVLSQLEEHSAYGGVVPEIAARAHVEALDTLVEEALDQAGVKLADVDAIAATSGPGLIGGLLVGLMTGKAIAKAAGKPLYAINHLEGHALTARLTDGLSFPYLMLLVSGGHTQLVLVRGVGEYERWGTTIDDALGEAFDKTAKLLGLPYPGGPAVENAAAKGDPDRFPLPRPMVGEARLDFSFSGLKTAVRQAATAIAPLSEQDIADICASFQKAVSRTLKDRIGRGLARFKVEFPHINGEPALVVAGGVAANQEIRQTLQALCDTHGFRFVAPPHRLCTDNAAMIAWAGLERMAEGRQADALEVAPRSRWPLDGSAETLIGFGKRGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_BRUO2
Sequence: MSTPLDHIRNFSIVAHIDHGKSTLADRLIQLTGGLDTREMKDQVLDSMDIERERGITIKAQTVRLSYKAKNGEDYVLNLIDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYQAIDNNHEIVVVLNKIDLPAAEPERVKQQIEEVIGIDASDAVEISAKTGLGIEDVLEAIVNKLPAPKEGDRNAPLKAMLVDSWYDSYLGVIVLVRVIDGVLKKGQTIRMMGTGAKYPVERTGVFTPKMVQVDDLGPGELGFITASIKEVADTRVGDTITEDRRPTENMLSGFKPAQPVVFCGLFPVDAADFEDLRGAMGKLRLNDASFSFEMETSAALGFGFRCGFLGLLHLEIIQERLEREFNLDLITTAPSVVYRLNMTDGTHKELHNPADMPDVVKIASIEEPWIKATIMTPDDYLGAIMKLCQERRGIQIDLTYVGPRAMITYDLPLNEVVFDFYDRLKSISKGYASFDYNLSDYREGDLVKMSILVNEEPVDALSMLVHRSAAEKRGRALCEKLKELIPQHMFKIPIQAAIGGRIVARETISALRKDVTAKCYGGDVTRKRKLLEKQKEGKKRMRQFGKVEIPQEAFIQALKMGDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RF1M_HUMAN
Sequence: MNRHLCVWLFRHPSLNGYLQCHIQLHSHQFRQIHLDTRLQVFRQNRNCILHLLSKNWSRRYCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFELLNYTPADYGGLHHAAARISGDGVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKLDPKDLRIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVLRARLYQQIIEKDKRQQQSARKLQVGTRAQSERIRTYNFTQDRVSDHRIAYEVRDIKEFLCGGKGLDQLIQRLLQSADEEAIAELLDEHLKSAK
What is the function of this protein?
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-cognate termination stop codons AGG and AGA.
What are the official names of this protein?
Peptide chain release factor 1, mitochondrial, MRF-1, MtRF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
Protein: RGF1A_HUMAN
Sequence: MPQTSVVFSSILGPSCSGQVQPGMGERGGGAGGGSGDLIFQDGHLISGSLEALMEHLVPTVDYYPDRTYIFTFLLSSRVFMPPHDLLARVGQICVEQKQQLEAGPEKAKLKSFSAKIVQLLKEWTEAFPYDFQDEKAMAELKAITHRVTQCDEENGTVKKAIAQMTQSLLLSLAARSQLQELREKLRPPAVDKGPILKTKPPAAQKDILGVCCDPLVLAQQLTHIELDRVSSIYPEDLMQIVSHMDSLDNHRCRGDLTKTYSLEAYDNWFNCLSMLVATEVCRVVKKKHRTRMLEFFIDVARECFNIGNFNSMMAIISGMNLSPVARLKKTWSKVKTAKFDVLEHHMDPSSNFCNYRTALQGATQRSQMANSSREKIVIPVFNLFVKDIYFLHKIHTNHLPNGHINFKKFWEISRQIHEFMTWTQVECPFEKDKKIQSYLLTAPIYSEEALFVASFESEGPENHMEKDSWKTLRTTLLNRA
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro).  Plays a role in cell migration.
What are the official names of this protein?
Ras-GEF domain-containing family member 1A.
Protein: HUTI_BOVIN
Sequence: MAGGHRLLLENARQVVLVCARGERFLTRDALRSLEVLEGASLVVGTDGFIKAIGPADAIQKQFSEETFEERIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMDIHQAGGGINFTVERTRQASEEELYSSFQQRLGCMMRAGTTLVECKSGYGLNLETELKMLRVIERARQELDIGISATYCGAHSVPKGKTASEAADDIIKNHLPRLKELGRNGEIHVDNIDVFCEKDVFDLDSTRRILQSGKDIGLQINFHGDELHPMKAAELGVELGAQAISHLEEVSDEGIAAMASARCSAVLLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTQGSLEVGKQGDLIIINSPRWEHLIYQFGGHHELIDYVIAKGKVIYKK
What are the official names of this protein?
Probable imidazolonepropionase, Amidohydrolase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
Protein: IUNH_CRIFA
Sequence: MPKKIILDCDPGLDDAVAILLAHGNPEIELLAITTVVGNQTLAKVTRNAQLVADIAGITGVPIAAGCDKPLVRKIMTAGHIHGESGMGTVAYPAEFKNKVDERHAVNLIIDLVMSHEPKTITLVPTGGLTNIAMAARLEPRIVDRVKEVVLMGGGYHEGNATSVAEFNIIIDPEAAHIVFNESWQVTMVGLDLTHQALATPPILQRVKEVDTNPARFMLEIMDYYTKIYQSNRYMAAAAVHDPCAVAYVIDPSVMTTERVPVDIELTGKLTLGMTVADFRNPRPEHCHTQVAVKLDFEKFWGLVLDALERIGDPQ
What is the function of this protein?
Catalyzes the hydrolysis of the N-glycosidic bond of commonly occurring purine and pyrimidine nucleosides into ribose and the base, but has a preference for inosine and uridine as substrates.  Is not active on thymidine and 2'-deoxynucleosides.  Functions in purine salvage from the blood of the host, a fundamental pathway since protozoan parasites such as C. fasciculata are incapable of de novo purine biosynthesis.
What are the official names of this protein?
Inosine-uridine preferring nucleoside hydrolase, IU-NH, IU-nucleoside hydrolase, Non-specific nucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family.
Protein: EFTU_PSE14
Sequence: MAKEKFDRSLPHVNVGTIGHVDHGKTTLTAALTRVCSEVFGSARVDFDKIDSAPEEKARGITINTAHVEYNSLTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPYIVVFLNKADLVDDAELLELVEMEVRDLLSTYDFPGDDTPIIIGSARMALEGKDDNEMGTTAVRKLVETLDSYIPEPVRLTDKPFLMPIEDVFSISGRGTVVTGRVERGIVKVQDPLEIVGLRDTTVTTCTGVEMFRKLLDEGRAGENCGVLLRGTKRDDVERGQVLVKPGTVKPHTQFEAEIYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGSCELPEGVEMVMPGDNVKVSVTLIKPIAMEDGLRFAIREGGRTVGAGVVAKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_VESOH
Sequence: MAKLDFITLGIESSCDETGVGLYHSELGLIGHKLFSSVEIHSEYGGVVPELASRDHIQRVLPLIKTVLTNAKFTLQDLSGIAYTAGPGLAGALLVGSALAKSLAWSLGVPSLAVHHMEGHLLAPLLEESQPKFPFVALLVSGGHTMLIDVKAIGQYKILGKSLDDAVGEAFDKTAKILGLGYPGGPALEMLAKQGDTNTFKFPLPMVNRPGLDFSFSGLKTFARNTFTKHPNKKSDIAKAFEVATTQILMIKCRRALEKTGRITLVVAGGVSANLSLRSELNQMGRKVGVNIFYPRQEFCTDNGAMIALAGHFRLSDGQCDTNYEINIKPRWNIEELSQIK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK3_PAUCH
Sequence: MSIGILGKKLGMSQFFDEEGKAVPVTLIEAGPCRITQLKSIDTDGYTAVQLGYGETRQKLVNKPSKGHLARSGEQLLSHLREYRVETIDGLKLGNSITVEDFKAGQKVDVSGDSMGRGFSGYQKRHGFSRGPMTHGSKNHREPGSTGAGTTPGRIYPGKRMAGRYGGKQITTRGLVIVKVDTGHNLLVVKGSVPGKPGSLLNIFPAKGVNSKFANGGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, organellar chromatophore.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore.
Protein: KDSA_RHOPS
Sequence: MNKSIAPAPVVAAGDVKFGNSLPLSVIAGPCQLESRAHALEVASALKEIATRLGIGLVYKTSFDKANRTSAASARGIGLDAALAIFAEIRDSVGLPVLTDVHEAEQCARAAEAVDILQIPAFLCRQTDLLLAAAATGRIVNVKKGQFLAPWDMGNVVAKITTAGNQKVLVTERGASFGYNTLVSDMRALPIMARTTGAPVIFDATHSVQQPGGKGTSSGGEREFVPVLARAAVAVGVAGVFIETHPDPDHAPSDGPNMVPLRDFEALLRTLMEFDALAKKRPGAGTI
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATMA_ASPFL
Sequence: MDSVLRYVFLLLAMTSFYMMYISLFNNGFFNLLSHQLATRALPGESDIALLSEYTGLKAFDGILESIVIFFWPISQGHHVGLSLTGLSFSGGMVGIWMIVVVHICRIRSFTRGMVITLIVGIAQQAVGPGIVIPCYFALTSRARPPNKNLHLTGTYSTSNHGLVVSMIMSYIFPLVIMSLPAPAMISPHSKQQVIAAWQGWPVYFVIIMTTHHLFINRGHRKEASARRQVLSVYHFGFACSCLCHMAWLSAFVASKIQSLSQSSNFWYLCPYGVAFPLLNQPAQRLGALEAGLFTFLQWDYCVAAAATMVWSTDRYIQECHRAELEIDKFRLILRLLGWILIDGPSATAVRLIWESEGPSYLQNPN
What is the function of this protein?
Aflatrem synethesis protein A; part of the ATM2 gene cluster that mediates the biosynthesis of aflatrem, a tremorgenic mycotoxin with acute neurotoxic effects (PubMed:19801473, PubMed:2867895).  Synthesis of geranylgeranyl diphosphate (GGPP) by AtmG (a GGPP synthase) precedes condensation of GGPP with indole 3-glycerol phosphate, followed by epoxidation and cyclization by AtmM (a FAD-dependent monooxygenase) and AtmC (a prenyltransferase) to produce paspaline (PubMed:19801473).  AtmB is also essential for paspaline production, but its exact role has not been identified yet (PubMed:19801473).  AtmP, a cytochrome P450 monooxygenase, subsequently converts paspaline to 13-desoxypaxilline via PC-M6 by removal of the C-30 methyl group and oxidation at C-10 (PubMed:19801473).  AtmQ, a cytochrome P450 monooxygenase, then catalyzes the oxidation of 13-desoxypaxilline, first at C-7 to produce paspalicine and then at C-13 to form paspalinine (PubMed:19801473).  Finally, AtmD prenylates paspalinine to form aflatrem (PubMed:19801473).  The role of atmA in the aflatrem biosynthesis is still unknown (PubMed:19801473).
What are the official names of this protein?
Terpene cyclase atmA, Aflatrem synthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound ascI terpene cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FIEF_SALHS
Sequence: MNQTYGRLVSRAAIAATAMASALLLIKIFAWWYTGSVSILAALVDSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQSMFISGSALFLFLTSIQNLIKPTPMNDPGVGIGVTVIALICTIILVTFQRWVVRKTQSQAVRADMLHYQSDVMMNGAILIALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDAERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDNLPLVQAHFVADQVEQAILQRFPGSDVIIHQDPCSVVPREGRKFELV
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1253_LISIN
Sequence: MKREARNYIDNKLKPPKAFFDWCFSQIPTYKWSNKKETILASNRKNCSVIEQKLRKNSRLTFFGKLNVFGIVLVTSKRIEIQSYAFWNRVVEGKEMIEFDLVNFEQFADGEHVKVAISDGKMWFGLIPIYGGMSGGPYSMIRLFENDWKEKIRSKSELKYLEIPHLDFKEIETIYKYRVEIEFLQKIKARQLSKEVMYPVTQYTNGSFRKTVDMRTINAKWLKENKPFFKNSDRGFMEFELARRIQKRRGKVVSGIEKYLDYRAINKIPEGVGIVRFQNWIIKNKVDFSYYLDYLNLMRDLNIAIDSENIIMPKNLVIAHDNAVKLLYQMKHEVEEQQYKMRFEKIKDLEKTIDNYAFIVPKQASDLLTEGKALSHCVGGSNYIKQHIEGKTTIIFVRDKQYLEKSLYTLEYKNGQIYQLRGKHNCEPTHDVQEAANNWAASVKSKTKVLQHS
What are the official names of this protein?
Uncharacterized protein Lin1253/Lin1744.
What is the protein family that this protein belongs to?
To S.faecalis plasmid PAM373 EP0012.
Protein: RL17_ASPFU
Sequence: MLGLCLHQVRYAAQDIPAAKSARARGSYLRVSFKNTRETAQAINGMKLQRALAFLENVKNKTEVVPFRRYAGSIGRTAQGKQWGVSKARWPVKSAQFLLDLLKNAEANADTKGLDTGNLIVKHIQVNQAPKGRRRTYRAHGRINPYMTNPCHIELILTEGEETVQKAPQVVKKEGAHLSSRQRGAQIRRALIEA
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.