PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_RUMCH
Sequence: MINLMNMTLEELEQMLSEMGQQKFRAKQIFKWINSGIRSFSDMTNISKQLRDELEKVSKISRLKIVDRLQSKIDSTVKYLFELEDGNIIESVLMEYKHGFTACISSQAGCRMGCKFCASTGAGFSRNLTPGEMLDQVMTMQEDSGNRIGHIVLMGIGEPLDNYENVIKFLKIVNHPDGLMIGMRNISLSTCGVVPRILQLAKENIPITLSVSLHSARDDKRSAMMPVNKTYCIDKLISACKIYTVSTKRRITFEYAMILGENDSEQDARELAGLLKGMLCHVNLIPVNTVTGNGYKKSSRIHIDKFKNILESKGIETTVRRELGSDINAACGQLRKNKIDSTTNLLLNS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E3GL_ADE03
Sequence: MGAILVVLALLSLLGLGSANLNPLDHDPCLDFDPENCTLTFAPDTSRLCGVLIKCGWDCRSVEITHNNKTWNNTLSTTWEPGVPQWYTVSVRGPDGSIRISNNTFIFSEMCDLAMFMSRQYDLWPPSKENIVAFSIAYCLVTCIITAIICVCIHLLIVIRPRQSNEEKEKMP
What is the function of this protein?
Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface.  Also delays the expression of class I alleles that it cannot affect by direct retention.  Binds transporters associated with antigen processing (TAP) and acts as a tapasin inhibitor, preventing class I/TAP association.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes (By similarity).
What are the official names of this protein?
Early E3 18.5 kDa glycoprotein, E3-19K, E3gp 19 kDa, E19, Early E3 19.2 kDa glycoprotein, GP19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E19 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RS7_LEPBA
Sequence: MSRRRGKVEPRHIEGDPKYNDKVISKFINCLMVDGKKSVAESVFYDALEVIAKKTGQDPFAVFQEALENAKPQVEVKSRRVGGVTYQVPIEVRPERRLALGIRWLIKYSRGRNEKSMKNKLAAEFMEAQKGTGSAIKKKEDIRKMADANKAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ILVD_LISW6
Sequence: MRSDKIKKGVEQAPARSLLHATGQIKSPGDMDKPFIAICNSYIDIVPGHVHLRELADVAKEAIREAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSREVIADAAETVINAHWFDGVFYIPNCDKITPGMLLASVRTNVPAIFCSGGPMKAGLSAHGKALTLSSVFEAVGAFKDGSMSQEDFLDMEANACPTCGSCAGMFTANSMNCLMEILGMAVPGNGTTLAVSDARRELIRESAFHLMDLVKKDIRPRDIITKDAIDDAFALDMAMGGSTNTVLHTLALANEAGIEDYDLERINDIAKRVPYLSKIAPSSSYSMHDVHEAGGVSAIVKELVDLGGAIHPDRITVTGKTIRENVADAKINNTDVIHPKENPYSPVGGLSMLFGNIAPKGAAIKVGGVDPSVQVFKGEAICFSSHDEAVEAIDNHTVREGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAAAGGPIALVHDGDIITIDLPNRTLNVDVSDEVLEERRKELPKFKAKVKTGYLARYTALVTSAHTGGILQIPEDLID
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PARL_RAT
Sequence: MALYSWVQRGWRCGQTWAPLLGGGYRELSATQARQLLGRRFNLLLQQKCGFRKAPRKVEPRRSDTGSSGEAYKRSALIPPLEETVFYPSPYPVRTLLKPFFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGNLRKEINKWWNSLSDGQRTVTGIIAANALVFCLWRVPSLHRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSTSIVNILGQEQFVAVYLSAGVISNFVSYVCKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPVFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYITYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK
What is the function of this protein?
Required for the control of apoptosis during postnatal growth.  Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals (By similarity).  Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP).  Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain (By similarity).  Required for processing of CLPB into a form with higher protein disaggregase activity by removing an autoinhibitory N-terminal peptide.
What are the official names of this protein?
Presenilins-associated rhomboid-like protein, mitochondrial, Mitochondrial intramembrane-cleaving protease PARL.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [P-beta]: Nucleus. Note=Translocated into the nucleus by an unknown mechanism.
Protein: PRS8_DICDI
Sequence: MVAQNNQQNKDETKGIKSYYCSKIEELEIKVNEKAQDLRRLEAQRNELNNRVRMLKEELQLLTNPGSHVAEVVKLMGKNKVLVKVNPEGKFVVDIDPTVDIAKLTPSTRAALKHESYTLHRILPNKIDPLVSLMKVEKIPDSTYDMVGGLDKQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFIMAREHAPSIIFMDEIDSIGSSRGESGSGGGDSEVQRTMLELLNQLDGFESTKNIKVLMCTNRIDILDPALLRPGRIDRKIEFPNPGDAGRLDILKIHSRKMNLTRGINLKKISDKMNGASGAELKAVCTEAGMYALRERRVHVSQEDFEMAVSKVMKKDSEQNMSINKLWK
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit 8, 26S proteasome AAA-ATPase subunit RPT6, Proteasome 26S subunit ATPase 5, Tat-binding protein homolog 10.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLMU_AERHH
Sequence: MSLNVVILAAGKGTRMRSSLPKVLHPVANKPMVSHVIETARKVGAEQLHLVYGHGAELLKERIQASDLNWVLQAQQLGTGHAVAQAIPFWQDEDDVLVLYGDTPLIQPETLQRLLAAKASDGMALLTVVLDNPTGYGRIVRSNGQVVGIVEQKDANAEQLAIREVNTGVLVANGGQLRSWLSRLDNKNAQGEFYLTDVIAMAHADNCPIAAVHPDDAMEVEGANNRVQLAQLERSYQKMQAERLMIAGATLIDPARFDLRGTLEIGEEVVIDVNVIIEGKVVLGNHVRIGAGSVLKDCVIGDHSEVKPYSVIEGAQIADQCSVGPFTRLRPGTVLEQDAHVGNFVEMKKARLGVGSKCGHLTYLGDAEVGAKVNIGAGTITCNYDGVNKFQTIIEDDVFVGSDTQLVAPVRIGKGATLGAGSTITKDVAENELVITRVPQRHIQNWARPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1FEH_AEGSP
Sequence: MAQAWAFLLPLLVLGSYVTSLFFPTYISNPLCGGDGGRSFHLCAQAPKDPDPPAVSTMYKTAFHFQPAKNWMNDPSGPMYFNGIYHEFYQYNLNGPIFGDIVWGHSVSTDLVNWIGLEPALVRDTPSDIDGCWTGSVTILPGGKPIIIYTGGDIDQNQAQNIAFPKNRSDPYLREWIKADNNPVLRPDEPGMNSIEFRDPTTGWIGPDGLWRMAVGGELNGYSAALLYKSEDFLNWTKVDHPLYSHNGSNMWECPDFFAVLPGNNAGLDLSAAIPQGAKHALKMSVDSVDKYMIGVYDLQRDAFVPDNVVDDRRLWLRIDYGTFYASKSFFDSNKNRRIIWGWSRETDSPSDDLAKGWAGLHTIPRTIWLAGDGKQLLQWPVEEIESLRTNEINHQGLELNKGDLFEIKEVDAFQADVEIDFELASIDDADRFDPSWLLDPEKHCGEAGASVPGGIGPFGLVILASDNMDEHTEVYFRVYKSEEKYMVLMCSDLRRSSLRPDLEKPAYGGFFEFDLEKERKISLRTLIDRSAVESFGGGGRVCITSRVYPAVLADVGRAHIYAFNNGSATVSVPQLSAWTMRKAQVNVEKGWSAI
What is the function of this protein?
Hydrolyzes inulin-type beta-(2,1)-fructans.  May play a role as a beta-(2,1)-trimmer during graminan biosynthesis (By similarity).
What are the official names of this protein?
Fructan 1-exohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: TILS_SALHS
Sequence: MTTLTLNTSLLSSCRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGECSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITAEGTLRLSPLMLMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKTVAGQHETTVVWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGVLHIVGRNGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAMB_ECO7I
Sequence: MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSGVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFATYAKWDEKWGYDYTGNANTNTNFGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: YACG_YERE8
Sequence: METEVIEVNCPTCGKIVIWGEQSPYRPFCCKRCQLIDLGEWADEEKRISSNGELSDSDEWSEEDPLQH
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: DXS_LISMC
Sequence: MSCFYLDLLKIKDPSFMKQLDIQELEALAADIRAFLITSTSKSGGHIGPNLGVVELTIALHYSFNSPKDKFIWDVGHQSYVHKILTGRASQFGTLREHGGLDGFPKRKESIHDVFETGHSSTSLSAAAGMVIARDIKKEEFYVIPIIGDGALTGGMALEALNHIGDMGKDMIVILNDNDMSIAPNVGAIHNILGKLRTSDTFKQTKAKVDGTFFEELGFMYLGPINGHDIEEVITNLELAKRTKGPVLLHIVTKKGKGYQPAELDSRGTWHGTGPYKVETGSFIKPAKRAASWSSVISNELIRLAEKDERIVAITPAMPVGSKLEKFAKAFPERFFDVGIAEQHATTMAAGLATQGMKPFLTIYSTFLQRAYDQLVHDVCRQKLNVVIGIDRAGLVGADGETHQGIFDISFLNSIPNMTISMPKDEVEARQLMDTAFSYNDGPFAIRYPRGEAPGAQVAESNTLIPIGKWETIIQPIDAVILTFGPTIRLALKAAEQLELEGYHVGVINARYIKPLDEALLHQILKQKIPILTVEESLLKGGFGASVLEFIEASNYSDVVMHRIGLPDEFISHGSVSIILESFGISTTGIVLKIKEMLAQSGKLRAKRL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PURA_PSYA2
Sequence: MGKNVVVLGSQWGDEGKGKIVDLLTEKASAVARFQGGHNAGHTLVVDGKTTILHLIPSGILREGVTCFIGNGVVLAPDALLKEMKNLEDNNVPVRERLRISPNCPLIMPYHVALDQAREAKRGSGKIGTTGRGIGPAYEDKVARRAIKLADLFRDDLEEKLRNLIEYHNFQLTQYYKVEAIDFDETLKLCQEWKEAIRGMVTDVTEDLNQLRLAGKNLMFEGAQGTLLDIDHGTYPFVTSSSVTAGGVSTGTGIGPLYLDYVLGITKAYTTRVGSGPFPTELFDDVGAHLAKVGHEFGATTGRARRCGWFDAEALRRAVVLNSMSGICLTKLDVLDGLEELLIGVGYNLPETECAGAHDAEFYESVTPKYETLQGWSESTVGITNYDELPENAKKYIKRIEVLIGCPIDIISTGPDREETIVLRDPYDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATA_STAAS
Sequence: MSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQFDREVIPERRMHAKGSGAFGTFTVTKDITKYTNAKIFSEIGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMRDAQNNWDFWTGLPEALHQVTILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFRTQQGIENLTDEEAAEIIATDRDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDNPFDLTKVWYHDEYPLIEVGEFELNRNPDNYFMDVEQAAFAPTNIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPNNHGKFDSQPEYKKPPFPTDGYGYEYNQRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMEGVTDDVKRRHIRHCYKADPEYGKGVAKALGIDINSIDLETENDETYENFEK
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: NFYA_BOVIN
Sequence: MEQYAANSNSSAEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.  NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.  NF-YA positively regulates the transcription of the core clock component BMAL1 (By similarity).
What are the official names of this protein?
Nuclear transcription factor Y subunit alpha, CAAT box DNA-binding protein subunit A, Nuclear transcription factor Y subunit A, NF-YA.
What is the protein family that this protein belongs to?
Belongs to the NFYA/HAP2 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPIA_RHOPB
Sequence: MSSDELKRQAAAAALEHVRDGMKLGLGTGSTAKHFVELLGERVRGGLNVVGVPTSEVTRADALRCGIALTTLDEVDRLDLTVDGADEINAALNLIKGGGGALLREKIVAAASDRMIVIADESKLVANLGRFPLPIEVNSFGLAATLRAIEEACAECGVFGPLSLRKGSDGHAFVTDGGHWIVDAQLGRIPDAPSLADQLNAIPGVVENGLFIGLASMAVLAGPNGIRIIERP
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PSBM_WHEAT
Sequence: MEVNILAFIATALFILVPTSFLLIIYVKTVSQNN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HGD_PSEPK
Sequence: MNRDTSPDLHYLSGFGNEFASEALPGALPVGQNSPQKAPYGLYAELLSGTAFTMARSELRRTWLYRIRPSALHPRFERLARQPLGGPLGGINPNRLRWSPQPIPAEPTDFIEGWLPMAANAGAEKPAGVSIYIYRANRSMERVFFNADGELLLVPEQGRLRIATELGVMEVEPLEIAVIPRGMKFRVELLDGQARGYIAENHGAPLRLPDLGPIGSNGLANPRDFLTPVAHYEEAEGPVQLVQKFLGEHWACELQHSPLDVVAWHGSNVPYKYDLRRFNTIGTVSFDHPDPSIFTVLTSPTSVHGMANMDFVIFPPRWMVAENTFRPPWFHRNLMNEFMGLINGAYDAKAEGFLPGGASLHGVMSAHGPDAETCEKAIAADLAPHKIDNTMAFMFETSQVLRPSLQALECPQLQADYDSCWATLPSTFNPNRR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: PSAJ_SYNPW
Sequence: MQKFLTTAPVVAAIWFTLTAGILIEWNRFFPDLLFHP
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CERK_ORYSJ
Sequence: MEGGGEALFLDGVGEVTVAVGDDGLSFQPLHQEVSSSCWSSIIMQPKLESKLKFSDVYAVELLEVGPVCEPWNARATVQGKINTEMNRFVIHTVTRPRKRPSPWVPCEYIFGHKDQQTCKTWVEHIKTCINKEQDRPKSLMVFVHPLCGKGRGCKNWETVAPLFERAKVKTKVIVTQRAGHAYDTLASLSDKDLKKFDGVIAVGGDGLFNEILNGLLSTRHTNSYPPTPEGFGYFRNNMKCQEHRNNDLSNSELTGDDANAISGSSNTPDDHEPLLSTTRSTGLDISSSDSSDEPCNGDQVPLVSFPNNWFRLGIIPSGSTDAIVLSTTGERDPVTSALLIILGRRISLDIAQVVRWKSSPSAEVSPTVRYAASFAGYGFYGEVIRESEKYRWMGPARYDFSGTMVFLKHRSYEAKVAFLENGNTHSLTASAENNANGVQTLQYHQNRHRKTICRTNCLICKGTSTSEQNSEDENPDSSRTACETPKWVWSKGRFLSVGAAVISCRNERAPDGLVADAHLSDGFLHLLLIRDCPLPFYLWHLTQFTKKGSDPLSFKFVEHHKTQAFTFISSHDESVWNLDGELLQACEVSVQAFRGLVNLFASGPEV
What is the function of this protein?
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate.  Possesses activity on ceramide analog (C6 synthetic ceramide) in vitro.  Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect.  Thus, ceramide phosphorylation plays a role in the modulation of PCD and CERK activity is crucial for the maintenance of cell viability.
What are the official names of this protein?
Ceramide kinase, OsCERK.
Protein: PHMT_MYCTO
Sequence: MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEEDPPMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTRTLHPASYTGLDLNQAGIKLCKKRHRLPGLDFVRGDAENLPFDDESFDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNNEIAAWEADLAATPLRQLSQRQINAEVLRGIGNNSQKSRDLVDRHLPAFLRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD
What is the function of this protein?
Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL).
What are the official names of this protein?
Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase family.
Protein: YCCT_SALSV
Sequence: MKTGALTTFLALCLPVTVFATTLRLSNEVDLLVLDGKKVSSSLLRGAESIELENGPHQLVFRVEKTIRLPGNEERLYISPPLVISFDTQLINQVNFQLPRLENEREASHFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASLPQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQPPS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: TCAL4_HUMAN
Sequence: MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Transcription elongation factor A protein-like 4, TCEA-like protein 4, Transcription elongation factor S-II protein-like 4.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family. TFA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEF2_BORPA
Sequence: MIHAILKMGDPRLLRVAAPVERYDTPELRALIDDMFETMAHAQGVGLAAPQIGVDLQLVIFGFERNDRYPDAPAVPRTILCNPVIEPLSDEMEDGWEGCLSVPGLRGLVPRYRHIRYSGYDPAGQRIEREAEGFHARVVQHECDHLIGRLYPTRIRDLTKFGYTEVLFPEMDPNAD
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 2, PDF 2, Polypeptide deformylase 2.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: UBIG_NEIMA
Sequence: MSDKKYNVDEGEIAKFSRIADKWWDKSGEFKTLHDINPLRLDYIDGHADLCGKRVLDVGCGGGILAESMARRGAAFVKGIDMAEQSLETARLHAALNNVADIEYECIRVEDLAEAEPHSFDVVTCMEMMEHVPDPAAIVRACAKLVKPDGMVFFSTINKNPKSYLHLIVAAEYLLKFVPKGTHDWKKFIVPAELARMCRQAGLDVADTKGMTYHVLSQTYALCDSTDVNYMFACRPAF
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: IF2_ROSDO
Sequence: MSDTDGKKTLGLRGGAPRPGNVKQSFSHGRTKNVVVETKRKRVVVPKAGATTSAGGKAPIGDPSRRPAGISDAEMERRLKAVKAAKAREAEEEAARIAEEKARAEERERRRAEQEERERAEREREESLKAKAEEDKRRKDEAEAAAKAAAAPAAEPVVQRPAAKAAPEPAPRKQQDRDRDNKRGGKGNDDSRRSGKLTLNQALAGGEGGRQRSMAAMKRKQERARQKAMGGQVEREKVVRDVQVPEAIVVSELANRMSEKVGEVVKALMNNGMMVTQNQAIDADTAELIVQEFGHRIVRVSDADVEDVIKEVEDDEADLKTRPPVVTIMGHVDHGKTSLLDAIRKAKVVAGEAGGITQHIGAYQVKTDSGQLLSFLDTPGHAAFTSMRSRGAQVTDIVVLVVAADDAVMPQTIEAINHAKAAEVPMIVAINKIDRPAADPTKVRTDLLQHEVIVEQMSGDVQDVEVSAITGQGLDDLLEAIALQAEILELKANPNRAAQGAVIEAQLDVGRGPVATVLVQNGTLRQGDIFVVGEQYGKVRALINDQGERVKEAGPSVPVEVLGLNGTPEAGDVLNVTSTEAQAREIASYRANAAKDKRAAAGAATTLEQLMANAKADEDVSELPILVKADVQGSAEAIVQAMEKIGNDEVRVRVLHSGVGAITETDVGLAEASGAPIMGFNVRANASARNTANQKGVELRYYSIIYDLVDDVKAAASGLLSAEIRENFIGYATIKEVFKVTGVGKVAGCLVTEGVARRSAGVRLLRDNVVIHEGTLKTLKRFKDEVAEVQSGQECGMAFENYDDIRADDVIEIFEREEITRTLT
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.