PharMolix/UniProtQA huggingface dataset:
Protein: MNMA_MARMM
Sequence: MTTDLTGRARAQADDLISRLGLAGDPLGLGGNPGDHRVVVAMSGGVDSSVTAALLHHLGYDVVGVTLQLYDHGAAMAKKGACCAGQDIYDAKRVAEACGFRHYVLDYESRFREAVIEEFADTYLAGFTPIPCVRCNQTVKFADLLTTARQLGAVCMATGHYIQRVDGPNGAELRRAADAGKDQSYFLFATTHDQLDFLRFPLGHLNKDQTRELAEAFGLIVADKPDSQDICFVPNGRYVDIVEKVRPGASRPGEIVHVDGRVLGTHEGVIRYTVGQRRGLKIAVGDPLYVVRLDAAKAEVVVGPREALEIDTIALKDINWLGDEAPLDGAPVRVKVRSTRPPVPAALSVDGDDIRVVLARGEEGVAPGQACVFYSSDDEDRVLGGGWITSTSGGSGGSSGVRLIG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_SHEHH
Sequence: MLNFFAAAPRGYEYALSLELAELGASEIKESVAGVYFSAPLELGYRITLWSRLASRIIFVIYKGPCESPEQLYNAAYGIDWQMQFSNRSTFSIDFHGLGGFIKNTQFGALKIKDAIVDRFRDDDFSRPNVERVDADFRIDAHFRRGEITIGFNFSGPALHKRGYRSTTGEAPLKENLAANMLVRSGWQAAQVDLLDPFCGSGTILIEAAMMACDIAPGIHRERFGFDHWLPHNKKVWEELLNEARARASIGKTRCEIKFYGSDIDSRLVALAKRNAENAGVLELIDFNVCNALDVKAPAGSGYLISNPPYGERLGNVTSLLQLYYQLGDKFKADFGGWSIAILNSDVELLSALKLKADKQMKMNNGALECAFNLYTVHALNTRRVDPANIKIEGDVSDIAVPFANRIKKNFKQLEKWAKKEGIDSYRLYDADIPEYNVAIDKYLDYVVIQEYSAPSEIPEAVTKRRLTDVLISLPSAIGIDPNHIILKTRERKKGTNQYEKLAASKLELITTEYGAKFKLNLKEYLDTGLFLDHRLTRKLVGEKSKGRSVCNLFSYTGSASVHAALGGATSVTTVDMSNTYIDWAKENFALNGLNSDKYQFVQANCLQWMKRTHDRFDLIFIDPPTFSNSKRMEDSFDVQRDHLAMLTDVFKLLNPGGEIIFSNNKRKFKMEIAELEALGMSVKNIDNQTLPLDYKRNPHIHNTWLITHAG
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIPK3_RAT
Sequence: MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSGCVFQERACPQIHVNGRHFGNPLPSTKGSAFQTKIPFSKPRGHSFSLQAGAIVVKDTAGATKVIAAQAQQAGVEAPRAVVWRNRLHFLGGPQRCGLKRKSEELDNHSGAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTSGEGDYQLVQHEVLCSVKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPVLQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCRETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDIVHVNTVMDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPIETLNHPFVSMKHLLDFPHSSHVKSCFHIMDICKSPSSCETNNHSKMSLLRPVASNGTAALAANFTKVGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCGDAFHQTLIICPPAIQGIPAAHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQTWSGRTQQMLIPAWQQVTPMAPAAATLTSEGMAGSQRLGDWGKMIPHSNHYNSVMPPPLLTNQITLSAPQPISVGIAHVVWPQPATTKKNKLCQNRSNSLQNTNVPHSAFISPKIISGKEVEEVSCVETQDNHTSEGEARTCHEASVRQDSSVSDKQRQTIIIADSPSPAVSVITISSDTDDEETSPRPSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDDEQESGCETVDGSPTSDSSGHDSPFAESSFVEDTPQNPELGTCAGTEAKPALSTAVEPPVGTERGLNVDAHMANTDSTCQPLTKGQPAPGKLNQPSASAARQQKPTSAFQQQHLNLSQVQHFGTGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAGSAHLGGQPTLLPYPPSTALSSAAPVAHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGINPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM
What is the function of this protein?
Seems to negatively regulate apoptosis by promoting FADD phosphorylation.  Enhances androgen receptor-mediated transcription.  May act as a transcriptional corepressor for NK homeodomain transcription factors.
What are the official names of this protein?
Homeodomain-interacting protein kinase 3, Androgen receptor-interacting nuclear protein kinase, ANPK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DET2_GOSHI
Sequence: MASDQTLFHYCLLTLYIIALPTWISLYFLQAPYGKHNRPGWGPTISPPLAWFLMESPTLWLTFFLFPSGQHFYNPKSFLLISPFLFHYFNRTVLYPLRLARNTTQTRGFPVSVAFMAFGFNLLNGYLQARWVSHYKDDYENEELFWWRFLAGLLIFVVGMWVNVRADKVLVGLKKQGDGGYKIPRGGLFELVSCPNYFGEIMEWFGWAVMTWSWVGFGFFLYTCANLMPRARATRLWYLEKFKDDYPKDRKAVIPFIY
What is the function of this protein?
Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide (BL) (PubMed:17565582).  Promotes cotton fibers (seed trichomes) initiation and elongation (PubMed:17565582).
What are the official names of this protein?
Steroid 5-alpha-reductase DET2, GhDET2.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNAJ_VIBPA
Sequence: MSKRDFYEVLGVSRDASERDIKKAYKRLAMKFHPDRNQGDESAADKFKEVKEAYEVLTDSQKKAAYDQYGHAAFEQGGGGFGGGFGGGGADFGDIFGDVFGDIFGGGRRGGGGHRAQRGADLRYNMELTLEEAVRGVTKEIEVPTLVHCDSCDGSGAKKGSSAETCGTCHGHGQVQMRQGFFAVQQTCPTCHGKGKIIKDPCNECHGQGRKQKTKTLNVKIPAGVDTGDRIRLSGEGEAGEMGAPSGDLYVQVHVKEHHIFERDGNNLYCEVPVSFAMAALGGEVEVPTLDGRVSLKVPSETQTGRMFRMRGKGVKGVRGGGIGDLIVKLVVETPVNLSSRQKELLKEFEESCGGEAATKHKPKSEGFFNGVKKFFDDLTS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_PSYIN
Sequence: MNIYIDENIPYARDFFTGHGNLHFFSGRNASAEQLIDADVLLVRSITEVNEKLLSLNKKLKFVGTATIGTDHIDQTYLKNRGIVFSSAPGCNKVSVAEYILSSLLVLADQQQFILSDKSIAIVGAGNTGTAVYQRLNALGMNCKLYDPPLLLAGDKRQFCTFEEVLEADIISLHVPKVVQGPFPTVHMFDSKVLSQLTNGQILLNAARGDLIDNQALLELAEQGLTPTLVLDVWENEPHINQQLLPYVAIATPHIAGYSLDGRVRGTEMLYQALCDFLQLKGKYTTADFVHRAAINSVSISKKIDQPLIKSLMHLIFDVRRDDALFREMIEDVDGFDTMRKTYQERRELSTLTVESSVEQNTLLQLLGFSTNVQNEIKETHEI
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB_CLOP1
Sequence: MKEKENSLFNSKMIKRAMKDSFIKLNPKIQLQNPVMFIVYIASILTTVLYVFSLFGIKDNSPSFILFISILLWFTVLFANFAEAIAEGRGKAQADALRSAKKDILANRIESIETKEKVSKVNSTELRKGDLIIVKAGEQIPADGDVVYGAASVDESAITGESAPVIRESGGDRSAVTGGTQVISDYIVVKVSNNPGESFMDKMIAMVEGASRKKTPNEIALQILLVSLTIIFLVVTASLYAYSEFASNQNGVINSTSVTSLLALLVCLAPTTIGALLSAIGIAGMSRLNQANVLAMSGRAIEAAGDVDILMLDKTGTITLGNRQASEFLPVDGANIEELADAAQLSSLADETPEGRSIVILAKEQFGIRGRDLSSSNAKFIEFTAKTRMSGVDFNGDEIRKGSAESIKKYITEHGGDFSDECEKKVEEIARKGGTPLVVAKNYKVLGIIYLKDIVKRGVKEKFSDLRKMGIKTIMITGDNPLTAAAIAAEAGVDDFLAEATPEGKLNMIKDFQKKGHLVAMTGDGTNDAPALAQADVAVAMNTGTQAAKEAGNMVDLDSSPTKLIEIVKIGKQLLMTRGALTTFSIANDIAKYFAIIPPLFIGLFPELSRLNIMNLQSPESAILSAVIYNAFIIIFLIPLALKGVKYREVSANKLLSRNLFVYGLGGIIAPFIAIKGIDILITMLGIV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METK_GEOMG
Sequence: MEMKDYIFTSESVSEGHPDKVADQVSDSILDAILAQDPRARVACETLVTTGMAVIAGEITTSAVVDYPKVVRETIREIGYNDSAMGFDWETCAVLVSIDKQSPDISQGVTEGEGMFKEQGAGDQGLMFGYACTETPELMPMSITYAHKLTQKLAEVRKNGVLDFLRPDSKSQVSVEYVDDKPVRVDTVVISSQHTPEVSYEAIKEGIIEEVVKKIIPAHLMDERTRMLINPTGRFVVGGPMGDCGLTGRKIIVDSYGGHGAHGGGAFSGKDPSKVDRSAAYMGRYVAKNLVAAGLCEKCEVQVAYAIGVAEPVSVMVDTAGTGKISSKRIAEIVREVFDLRPRAIIEQLDLLRPIYRKTAAYGHFGRELPEFTWERTDKVYMIRQKAGI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_SALCH
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFNESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTMGAGVAVDQAGLSASAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: Y1073_RICCN
Sequence: MDIKLLYRLAKYLRCYKKDLIIVMISLLSVSASLLLIGSVFRNLVDKGLSKDHISSVDNSILYICLLIIILSIASFFRSYFINNVAEKAVNQIRKEAYSNLINYEIEEFEELKIGDIISRLTNDIDQISTLIVNFLSFFIRNSVMLIGSITLMFFESFKLASIVIITIPILLIPLIKFGKHVKVLSKKALESKSLLASDINETFNNIRAIYAFNHQINKIADFDTKLQNYLIYCKTRLKIRALFFAISIAVIFLAITLVVWIGASDIVKGHLSAGQIISFIYYAIIAGVSCGGIFELLSEMHLPVTALERIITIIDKTPIAHNNYLELNNSDPISIEFKNVDFTYHSRPNLRIINNMSLKINANKFLGIVGRSGAGKSTVIQLLLRFYRQENGTILINNQDITLLNPAEIRKLIAYVPQEASIFSGTIKSNIIFGNNEASDDEINEIIKITGIEEFAAKLHDGINAKIGERGVRLSGGQKQRIAIARALLRMPQILLLDEAMSALDTMSEQKLLESIKKIMRGNIIISIAHRISSIESADYILVIDKGGVVAEGSHNDLSKNSEIYRNICREQLTI
What is the function of this protein?
Part of an ABC transporter complex.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Putative export ATP-binding/permease protein RC1073.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_LISW6
Sequence: MAVKIRLKRIGSKKKPFYRIVVADSRFPRDGRSIETIGTYNPLLDPVEVKIDEEATLKWMHNGAKPSDTVRNLLSREGIMEKFHNQKLGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ZAPD_SALNS
Sequence: MHTQVLFEHPLNEKMRTWLRIEFLIQQLSINLPIADHAGALHFFRNISDLLDVFERGEVRTELLKELERQQRKLQAWVEVPGVDQDRIEALRQQLKSAGSVLISAPRIGQQLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLQQAQRDAQIETWLASLNPLTQALTLVLDLIRNSAPFRKQTSLNGFYQDNGDDADLLRLMLTLDSQLYPQISGHKSRFAIRFMPLDSENGLVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: SYDND_PSEAE
Sequence: MMRSHYCGQLNESLDGQEVTLCGWVHRRRDHGGVIFLDVRDREGLAQVVFDPDRAETFAKADRVRSEFVVKITGKVRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFPLDEYSDVGEETRLRYRFIDLRRPEMAAKLKLRARITSSIRRYLDDNGFLDVETPILGRPTPEGARDYLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDIETSFLDESDIIGITEKMVRQLFKEVLDVEFDEFPHMPFEEAMRRYGSDKPDLRIPLELVDVADQLKEVEFKVFSGPANDPKGRVAALRVPGAASMPRSQIDDYTKFVGIYGAKGLAYIKVNERAKGVEGLQSPIVKFIPEANLNVILDRVGAVDGDIVFFGADKAKIVCDALGALRIKVGHDLKLLTREWAPMWVVDFPMFEENDDGSLSALHHPFTSPKCTPAELEANPGAALSRAYDMVLNGTELGGGSIRIHDKSMQQAVFRVLGIDEAEQEEKFGFLLDALKYGAPPHGGLAFGLDRLVMLMTGASSIREVIAFPKTQSAGDVMTQAPGSVDGKALRELHIRLREQPKAE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Is 1. 5 times more efficient at aminoacylating E. coli tRNA(Asp) over tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_PSEAB
Sequence: MVQSAPASEIAALILRGFDDYREQFREITDGARARFEQAQWQEAQRASTQRINLYEEKVAETVAGLRVGLADSELLDVERWPIIKSAYIAQIDLRLDDELAETWFNSIFCGLFSHDNISDGTMFVHTTRPSLRAHARAPYTRTYRPGGDLRQALEKIFDDYRFDVPYDDRERDLERIDALLHSNLPDWVCKDPDLAIELIGSVFYRNKGAYLVGRLFTPDEQWPLVFPLLHREGHGIQFDTVITDEAEVSIIFSFTRSYFMVDVPVPAELVAFLKRLLPGKHLAELYTSIGFYKQGKSEFYRALINHLATTDDRFVMAPGVRGMVMSVFTLPGFNTVFKIIKDRFNPSKSVDHATVIQKYQLVKNHDRVGRLADTQQFADFRFPVSKFEPECLAELLEVAPSTVVMEGDVVLIRHCWTERRMTPLNIYLENASEAQTREALNDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEICYLTEVNFRYIPEPRFPEDEMSSEPWYSVGPNDVFPEEFPRFLFVDLNQRRLFAKLHGNLYDAKYWQGLQEQIREGKVIDVFPYRRQETPEQLLG
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_STRZP
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEGNEETTEVVVDTAVETVEETVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: TM183_MOUSE
Sequence: MARGSGQLGGPHRDTVTMPKRGKRLKFRAHDACSGRVTVADYANSDPAVVRSGRVKKAVANAIQQEVKSLCGLEASQVPAEEALSGVGEPCDILDSSDEMDAQEESTQERSVSRKKKSKRHKEDPDGTGEEYPMDIWLLLASYIRPEDIVNFSLICKNAWTVTCTAAFWTRLYRRHYTLDASLPLRLRPESMEKLRCLRACVIRSLYHMYEPFAARISKNPAIPESTPSTLKNSKCLLFWCRKIVGNRQEPMWEFNFKFKKQSPRLKSKCMERLQPPIQYQDVHTNPDQDCCLLQVTTLNFIFIPIVMGMIFTLFTINVSTDMRHHRVRLVFQDSPVRGGQNLRSEQGVQVVLDPVHSVRLFDWWHPQYPFSLRA
What are the official names of this protein?
Transmembrane protein 183.
What is the protein family that this protein belongs to?
Belongs to the TMEM183 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MENE_BACCR
Sequence: MMETMPNWLMQRAFLTPDRTAIEIEEEKVTFMELHEKVVSVCEHLTHVGVERGQKVAVLMKNGMEMITVIHALSYVGAVAVLLNTRLSREELLWQMDDAEVVCLVTDQDFDAKDVPVYSLAEVMNGPKEEASIQEEFSLEEAMTIIYTSGTTGKPKGVILTYGNHWASAVGSSLNLGLRDDDCWLACMPMFHVGGLSLLMKNIMYGMRILLVPKYDADFIHKALQTRGVTIISVVSKMLTDLLERLGAETYPSSLRCMLLGGGPAPKPLLEACVEKGIPVYQTYGMTETSSQICTLSADYMLTKVGSAGKPLFQCQLRIEKDGVVVPPLVEGEIVVKGPNVTGGYFNREDATRETIQNGWLHTGDLGYLDEEGFLYVLDRRSDLIISGGENIYPAQIEEVLLSHPAVAEAGVVGMSDDKWGQVPAAFVVKSGAVTEEEILHFCEEKLAKYKVPKKACFLEELPRNASKKLLRRELRQLVEEM
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: Y1290_METJA
Sequence: MKKAIYLLILCIFGLFSVYFTYAENISDISNTTSKNISSSNISHNNIIYSNINYNEILYIIVKNNTAYVKDVINGTNNPYHIKSAGIILYEKIYGYNYSNLLYRNSSNSLIFYYNFSVDKINYTINITIPQIEDYVGSLGGPIRMRIPPNNVKIIIVAENKLAETNGKYILEYNKTDKKVISLIYLDNVSSICNIYYTKFFNSSEFYGYAVANVTSITENRTSYTIKNPKGTFTFDRKYNVFVSNKTAYLKEPYLYVKLYNSTIDDIIILENNKISENSTKFMSNYLLSFIGIIIGFGIIGLAIYLSKRGRK
What are the official names of this protein?
Uncharacterized protein MJ1290.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RXLAC_PHYIT
Sequence: MLRSFLLIVATVSLFGQCKPLPLATSPVSDAVRAPHRSTHETRFLRTNDEERGATMTLAGVLRDKAQTKQLLTSWLNSGKSVPSVSNKLGLKRMSLEQAIHHENWKALTTFQRMKSKKAKAYAKYGTGYQTEAKTKENLLQWVMRGDSPKEVSSTLGLLGLSRRKIIDHQNYEAFRTFLKYRKQWAEMQGNGFTKLTT
What is the function of this protein?
Secreted effector that promotes P. infestans colonization of plant host (PubMed:30329083, PubMed:31217198).  Specifically suppresses Avr4/Cf4- and AvrPto/Pto-triggered cell death (PubMed:31217198).  Targets the potato MAP3Kbeta2 kinase, a positive regulator of cell death associated with plant immunity, and perturbs signaling pathways triggered by MAP3Kbeta2 (PubMed:31217198).
What are the official names of this protein?
Secreted RxLR effector protein PITG_22926.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host nucleus, host nucleolus. Note=Is secreted from haustoria to be delivered into host cells.
Protein: GRPE_FRATH
Sequence: MSKQEKSNVEDKSLDIETAAQVETAQESASGALEELSVEEQLERAKDTIKELEDSCDQFKDEALRAKAEMENIRKRAERDVSNARKFGIEKFAKELLPVIDSIEQALKHEVKLEEAIAMKEGIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNPEFEDNTIFDVFQKGYMLNGRIVRAAKVVIVKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGLUS_METJA
Sequence: MIPSYVPPKYKVEVDPNRCMLCERCTIECSWGVYRREGDRIISYSNRCGACHRCVVMCPRDAITIKENAISWRSHPLWDVDARVDIYNQAKTGCILLSGMGNAKEHPIYFDKIVLDACQVTNPSIDPLREPMELRTYIGKKPKQLEFEFVEEEIDGKKIKKAKLKTKIAPNLKLDTPIMIAHMSYGALSLNAHLSFAKAVKECGTFMGTGEGGLPKALYPYADHIITQVASGRFGVNEEYLMKGSAIEIKIGQGAKPGIGGHLPGEKVTAEISATRMIPEGSDAISPAPHHDIYSIEDLAQLVRSLKEATRWKKPVFVKIAAVHNAPAIAVGIATSDADAVVIDGYKGGTGAAPKVFRDHVGIPIEMAIAAVDQRLREEGLRNEISIIASGGIRCSADVFKAIALGADAVYIGTAAMVALGCRVCGRCYTGLCAWGIATQRPELVKRLDPEVGARRVANLIKAWTHEIKELLGAAGINSIESLRGNRDRLRGVGLNEKELEVLGIKAAGE
What are the official names of this protein?
Archaeal glutamate synthase [NADPH], Archaeal NADPH-GOGAT.
What is the protein family that this protein belongs to?
Belongs to the glutamate synthase family.
Protein: EIF3D_CRYNB
Sequence: MANFVLPPIHDNSDGSWGPSTSTLPAQFKDIPYAPFSKSDKITRIADWHDPQAEAAAGTRTARTVQSGGRRTAYGAAEGTVFGFVHDEDEKSFSLVDSGVRVGARGKAPIRGRSVRGVASARGARGRGGQRGGFSTRGGRGGARGGYGDWNKPQRTRDSSVTIGPEWEVLEEIDFNRLSKLSLSVEDPEDLASYGTVQAYDKTFDRINTRNEKPLEIVNRVRYNPSTSDDPIISQYAEKKEAQIFATDSILAVLMCAGRSVNSWDIIIEHRNGQVFFDKRESGPLDYITVNENAADPPVDSDDVSNINSAGSLSLEATYISHNFSSQVSANSKSKAYTPNPNPFYSPEVESEPPASTLYKYRKFDLSIDEEEQFSVILRTEADAYLGKKEVLVTVKALNEYDPRVQGGSGKPLDWRKNLDTQKGAILASEMKNNSAKFARWAIQSILAGVEQMKMGYISRANPRDAQRHTIVGVQSFKPLDFARQMNVSLANGWGIVRTIADLVLKQPEGKFVLVKDPNNPLVRLYKVPDDTFEAGAEEEEEEQDEE
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_RHIME
Sequence: MGRVLTAIGLMSGTSMDGIDIAVVRTDGDSIVDRGPSAGYAYDPRFRERLKQGLEDARSILKREERPGTLADLERDLTLRHALAVRMFLQENNILPDNVNVIGFHGQTVLHRPDQALTVQLGDGELLARETGIDVVYDMRANDMTHGGQGAPLIPAYHAALARGLSKVGEIATPVVFVNIGGISNLTYIGAGEEIVAYDSGPGNTLIDQWVEAHAGIPYDQGGMIASEGGVLRELADRYLSHPFFSAEKRRSLDRNDFAPPAAGDASLEDGARTLAHVTAAGIVRSARHLPANPATYIVCGGGRLNSVIMSDLHALAEAEGARVLAAEALDLNGDSMEAEAWAYLAVRSRYCLPLTYPGTTGVSCPVSGGRLAAKPGRIAAVS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.