PharMolix/UniProtQA huggingface dataset:
Protein: PYRI_CLOB1
Sequence: MLTINSIKNGIVIDHIQAGHGIKIFKYLGLEEADYRVALIMNAESSKLGKKDIIKIENIMEIDYKVLGFIDPTITIDVIENETIKEKIKLELPKTIENVIKCKNPRCITSIENYIPNEFYLVDEENGEYRCKYCDEIYSGGDINKL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: HSCA_SALAR
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLPDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTISSVKRMMGRSLADIQSRYPHLPYRFQASENGLPMIETAAGLLNPVRVSADILKALAARASESLSGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISILRLSCGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAIAAKIALSDADTVRVNVAGWQGEITREQFNDLIAALVKRTLLACRRALKDADVDPQEVLEVVMVGGSTRVPLVRERVGEFFGRTPLTAIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELAQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGIEASIQVKPSYGLTDSEIASMIKDSMSFAEQDVKARMLAEQKVEAARVLESLTGALTADAALLSAAERQCIDDAAAHLNAVAQGDDVDAIEQAIKNVDKQTQEFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL24_PYRAE
Sequence: MSFTTSAQPRKQRRSLYKAPLHLRRKLFNAKLSPELAKKLGVKRLPVRRGDTVLILRGDFKGVTGKVVKVDLKRVRIYVEGATRTNSRGQTVYYPIHPSKVMIVDVDLSDKARQKIIERRKKK
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MLTC_SALPA
Sequence: MKKLLALAVIAPLLISCSSSTKKGETYNEAWVKDTNGFDILMGQFANNIENLWGYKEVLIAGPKDYVKYTDQFQTRSHINFDDGTITVETIAGTEPTAHLRRAIIKTLLMGDDPTSVDLYSDVDDIKISKEPFLYGQVLDNTGQPIRWEGRATTFADYLLKTRLKSRSNGLRIIYSVTINLVPNHLDKRAHKYIGMVRQASRKYGVDESLILAIMQTESSFNPYAVSHADALGLMQVVQHSAGKDVFRSQGKSGTPSRNFLFDPASNIDTGTAYLAMLNNVYLSGIENPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANMINRMSPGDVYQILTTRHPSAESRRYLYKVNSAQRSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CHLB_PROMT
Sequence: MELTLWTYEGPPHIGAMRIATSMKKLHYVLHAPQGDTYADLLFTMIERRGSRPPVTYTTFQARDLGGDTAELVKGHIKEAVDRFKPETLLVGESCTAELIQDQPGSLAKGMGFDIPIVSLELPAYSKKENWGGSETFYQIVRTLLKDHSNESKHTWQEEKRRPRVNLLGPTLLGFRCRDDVLEIQKLLGQYGIDVNVVAPLGASPADILRIPNADVNVCLYPEIAESTCIWLERNLNIPFTTTVPLGVGATQDFLKELHKVLEMEIPQSVNESNNSKLTWYSNSVDSNYLTGKRVFIFGDGTHALAAARIANEELGFKVVGLGTYSREMARKVRPAAKALGLEALITNDYLEVEDAIKETSPELVLGTQMERHSAKRLGIPCAVISTPMHVQDVPARYSPQMGWEGANVIFDDWVHPLMMGLEEHLIGMFKHDFEFVDGHQSHLGHLGGKGTQNTNKEAIKTNLQDSVITDSDPIWTHEGEKELSKIPFFVRGKVRRNTENYARQAGCREINEETLYDAKAHYKA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: GRCA_VIBPA
Sequence: MIQGIQITKAANDELLNSIWLLDSEKNEARCVAAATGYEADQVIAISDLGEYESREVAIETAPRIEGGQHLNVNVLKRETLEDAVAHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTETL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: DEOD_HELPJ
Sequence: MTPHINAKIGDFYPQCLLCGDPLRVSYIAKNFLQDAKEITNVRNMLGFSGKYKGKGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIVMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKIGNVFSSDFFYSFETHAFGLMAQYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERIESFDNMITLALEMMS
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: G3P2_DROME
Sequence: MSKIGINGFGRIGRLVLRAAIDKGANVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYIVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCGVNLDAYKPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGASYDEIKAKVQEAANGPLKGILGYTDEEVVSTDFLSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQSKD
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, Glyceraldehyde-3-phosphate dehydrogenase II, GAPDH II.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECF_YERPS
Sequence: MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTYSDKKALAEAVIARAQADRSARFFWHGQFNATLWLALLSGKIKPGQVYWHVWGADLYEDAKSLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPASLLYFPTRMDPALTAINIDKPLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLALFSQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPFWQDLAEQHIPVFFYGDTLDEPLIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEHP
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEXA_BURVG
Sequence: MTKLTARQQQVFDLIRRAIERSGFPPTRAEIAAELGFSSPNAAEEHLRALARKGVIELAAGASRGIRLLGIDDMPHQFTLPHAGLMQLSLPLVGRVAAGSPILAQEHISQHYACDPALFTSKPDYLLKVRGLSMRDAGILDGDLLAVQKRTEAKDGQIIVARLGDDVTVKRLMRRPGGIELIAENPDYENIFVKAGSAEFALEGIAVGLIRSGEL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RS20_UREPA
Sequence: MANIVSNEKTYRHTQKVRKENHAKMSKLRTIVKKTRSSNEQAQLNEAYKVIDTTASKGVIHKNKANRLKSRTAKAFKTNLEVTA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: VG03_BPMD2
Sequence: MALMQATHTIEGFLAVETHPRAFVAENGHVITRLSATKWGGWEGLEILEYSGDGQVEVSDEQLAEAEHASQIEAQIIAEAAAE
What are the official names of this protein?
Gene 3 protein, Gp3.
Protein: LRRD1_HUMAN
Sequence: MSEKEGMSEVLEDTISQFRKESRSQSMKEPGFIKETSNLINEASDYLEGKSSNQIYETHPRQNTLESTSSSGRKSKRNEEQKKNLQFSETSTRTGTSQSLSSLTGRTAEYQALVNFLSHETVGEVSPQVSEENQKQLGLGADNFTVNLEAKGLQEFPKDILKIKYVKYLYLDKNQIKTFQGADSGDLLGLEILSLQENGLSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKALCFLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLLKIKELQLADNKLEVISHKIENFRELRILILDKNLLKNIPEKISCCAMLECLSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKITDCISHLNNICSLEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFPLGLCALDSLYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAIYNIFSLKEINFDDNPLLRPPVEICKGKQLYTIARYLQRADERDEKILEKIFKIVANNITETNFEFLCQKLNLANSETDMPTKSTVSLSERAHQALVIWKTQSNKLSLTAAALRDQLIRALTMIGAYEIMDKITALNLFTRAIKF
What are the official names of this protein?
Leucine-rich repeat and death domain-containing protein 1.
Protein: MNHD2_STAES
Sequence: MMSNLIILPMLLPFVCALILVFTKNKNRISKILSITTMIVNTMISIALLIYVVNHKPITLDFGGWKAPFGIQFLGDSLSLLMVSVSSFVVTLIMAYGFGRGEKRVNRFHLPTFILLLTVGVIGSFLTSDLFNLYVMFEIMLLASFVLVTLGQSVEQLRAAIVYVVLNILGSWLLLLGIGMLYKTVGTLNFSHLAMRLNHMENNQTITMISLVFLVAFSSKAALVIFMWLPKAYAVLNTELAALFAALMTKVGAYALIRFFTLLFDHHPSVTHTLLVFMACITMIIGAFGVIAYKDIKKIAAYQVILSIGFIILGLGSHTISGVNGAIFYLANDIIVKTLLFFVIGSLVYMSGYRNYQYLSGLAKREPFFGVAFVVVIFAIGGVPPFSGFPGKVLIFQGAITNGNYIGLALMIVTSLIAMYSLFRVMFIMYFGDADGEQVQFRPLPIYRKGLLSVLVVVVLAMGIAAPVVLKVTEDATNLNMKEDVFQKNVNTHLKEVNHK
What are the official names of this protein?
Putative antiporter subunit mnhD2, Mrp complex subunit D2, Putative NADH-ubiquinone oxidoreductase subunit mnhD2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYP9_SCHPO
Sequence: MMDGASPVDRDVSPVGLPKKRIKQNHDQVFLHNLPDAPRYTKSYMHNAEIYKCFPTKSNYILSVSYDGYVKFWHKTPNGVEYIKEFHAHNAMLLSAELSQDERLFITGADDKSLKVFDVESIDLVNIIDLEFLPKAICCFNSPSLKTSLIAVSSAESPLIFFFESGGDGEVLYTVKKHTAPVHCLRYLSTLDCFLSIDIGGMVEYWSPEEPFQKPDTAELFNMKSQTDLYIFKKQKSVPTSLEVSHFENFWSTISYPDCKVRVFDTKSGRAILELDENPSNAAKKVEALFEKEDTESSYYMSHVELGRRIAIERDIEKHGLTVGTTAIFDESEKYLLYGSIVGIKVVSIDNGTVVRIYGKDEAVRFTRLSLYQQAPKKSNLPSLDVIASNNPLVEESFQKDPTLFATAWKKQRFYLFSNMSTKFTLSDRDVYNEQVLPVTNNEGRQENGNILLGKAAIIHTTQGDISIKLYPEEAPKAVQNFTTHAENGYYDNTIFHRIIKNFMIQGGDPLGDGTGGESIWKKDFEDEISPNLKHDRPFTVSMANSGPNTNGSQFFITTDLTPWLDGKHTIFARAYAGLDVVHRIEQGETDKYDRPLEPTKIINISIVYT
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase 9, PPIase cyp9, Cyclophilin 9, Rotamase cyp9.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: RL27_CAMC1
Sequence: MAHKKGQGSTQNNRDSIGRRLGVKKFGGEFVRAGNIIIRQRGTATHAGNNVGLGKDHTIFALVDGFVKFERLDKNRKKVSVYPAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS5_BARBK
Sequence: MAQKERSDHNDSDERRNESGGEFIDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATESAKREMIYVPLRSGRTLHHDVEGRHGAGRVLLRSASAGTGIIAGGSMRAIFETLGMQDVVAKSLGSSNPYNMVRATFDALKRQMHPRDIAAQRGIKYSTLQARRQYIVGMEE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y260_SYNY3
Sequence: MFSSSVELELFFIFVLVVLNGIFSGSEIAIVSARKVRLEQLAKRGNRKAKLALKLATAPNNFLSAVQIGITLIGILTGAVGGATVALRLAEFLDDIPLLAPYAGPLSISLLVGFITYLSLVVGELVPKRIALSHPEHIACGVAPAMHLVAQLTAPLVYLLGVSTDAVLRLFGITSKEASPITEEEIRVMIEQGAQAGMIDEAEQEMVERVFRLGDRPVKTLMTPRTAIAWLDVESDWEENQQEILDTPYSRFPVGRDSLDECLGFVRVKDILNSQWSGQKINLEEIVQPPLFVAENTRSLHVLEMFRASGTHLALITDEYGGIEGLVTLNDLIEAIVGSIPNDDEIQEPQIIQREDGSYLLDGLLPIDEFKEIFDIETLSNEEEGHYHTLGGFVIESLGKIPQSGDYFVSDTLRVEVVDMDGIRIDKVLVNQLPEDSSTTEEESETDN
What are the official names of this protein?
UPF0053 protein sll0260.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL3_MYCCT
Sequence: MKGILGRKVEMTQVFTNSGQLVPVTVVEVLPNTVLQVKTIDSDGYVAVQLGTTDKRVNLVNKPELGHFKKANSNPKRFVKEIRNMQGYEIGQVINVSDIFVSGEYVDVTGISKGKGFAGGIKRHNYSRGPMAHGSGYHRGIGSMGAIINRIFKSKKMPGHMGNAKRTIQNLEIIAIDQSNNIMLIKGSIPGPKNSFVQIKQNVKGMSSKQAVELLNRNASVQA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GPMA_STRP4
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PSN2_MICMU
Sequence: MLTFMASDSEEEVCDERTSLMSAESPSPRSCQEGGQGPEDGDSTAQWRIQDSEEDGEEDPDRYVSSGVPGRPPGPEEELTLKYGAKHVIMLSVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVSQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLVLTVWNFGAVGMVCIHWKGPLMLQQAYLIAISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSLGEPSYPEVFEAPLPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLVFYFSTDNLVRPFMDTLAYHQ
What is the function of this protein?
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein).  Requires the other members of the gamma-secretase complex to have a protease activity.  May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane.  May function in the cytoplasmic partitioning of proteins.  The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis.  Is a regulator of mitochondrion-endoplasmic reticulum membrane tethering and modulates calcium ions shuttling between ER and mitochondria.
What are the official names of this protein?
Presenilin-2, PS-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: GABPA_HUMAN
Sequence: MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQCSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTVEVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEILWSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAPRISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN
What is the function of this protein?
Transcription factor capable of interacting with purine rich repeats (GA repeats).  Necessary for the expression of the Adenovirus E4 gene.
What are the official names of this protein?
GA-binding protein alpha chain, GABP subunit alpha, Nuclear respiratory factor 2 subunit alpha, Transcription factor E4TF1-60.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
Protein: Y593_MYCPN
Sequence: MNKKESTTTKKQWFKKCSFKKLKAEICNMLPTTPHNTKRTLIWVIVFSFITFLSFIFAYVCFNYAPVSTGFLYFLGAVFLLIGFAFAILSFVAMVKFVADYFANRFSNTQLKMDCDCAKTKK
What are the official names of this protein?
Uncharacterized protein MPN_593.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABZ_ANAMM
Sequence: MTMALDHKQIMRMLPHSYPFLLVDRVLECIPGKSIVALKNVTFNEPFFVGHFRDNPVMPGVLIIESMAQSSMLCVVSDREGDEASGNRSVYFMSIDGAKFRRVVVPGDTLTIKSAVIHMRGTTCKFQCHAYVGDELASEAQILAMMG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_SYNPW
Sequence: MDPSTLISRLEAARSSFHNLERQLADPDVASDPTRLQSIARERSRLEPLVNDYASLQAVQSEREQARELLRDSRGDEEMAHLAQLELDELDIRHEALIERLTLALLPRDPRDERSVMLEIRAGAGGDEACLWAGDLARMYERFSSRRGWTVQPVSASEADLGGFKELILSVKGESVFSELKFEAGVHRVQRVPATESQGRVHTSTATVAVMPEADPVEVQIEPADLEISTARSGGAGGQNVNKVETAVDLMHRPSGIRVFCTQERSQLQNRERAMEILRAKLYERQLAEANARESSARRAQVGTGDRSEKIRTYNAKDNRVTDHRLGRNFSLDPVLQGQMEDVIGACIAEEQRSKLEALSRQSDD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_HERA2
Sequence: MHLTPREQEKLLIVVAADLARRRQARGLKLNYPEAVAIITAELLEAARDGKSVAEIMSYGTTILTVDDVMDGVANMIHEVQVEATFPDGTKLVTVHDPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_UREP2
Sequence: MAKFIKSAHYFDQYPIDKQFEICVIGRSNVGKSSLINALANKKIARTSNTPGRTQLVNFFDFNNFRLVDLPGYGFAKVSKEKQTDLAAIIDQYLGYRQNLCAVFQICDINVLTNDDVEMSRYFENQKYAHFVVLNKLDKVNKSYFNNNKHKIAKFLNISTDRLLCVSAQNNINIITLFALMKKVVIQAKQEKILSKKEEKMSSEEEIK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: YHFK_ECOLI
Sequence: MFPPMWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVPACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLLLAKDVPLPFLLTGLTLVLGVTAELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQPLRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLSAQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARLRVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPLYARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWILMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASYLILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQWQSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEPAFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQRLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPHHGIWLSRKLRDSKA
What are the official names of this protein?
Uncharacterized protein YhfK.
What is the protein family that this protein belongs to?
Belongs to the YccS/YhfK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NEB2_HUMAN
Sequence: MMKTEPRGPGGPLRSASPHRSAYEAGIQALKPPDAPGPDEAPKGAHHKKYGSNVHRIKSMFLQMGTTAGPSGEAGGGAGLAEAPRASERGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPSAQPAPPPHPPSRLQETRKLFERSAPAAAGGDKEAAARRLLRQERAGLQDRKLDVVVRFNGSTEALDKLDADAVSPTVSQLSAVFEKADSRTGLHRGPGLPRAAGVPQVNSKLVSKRSRVFQPPPPPPPAPSGDAPAEKERCPAGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTVATAASPAPEEPKAQAAPEKEAAAVAPPERGVGNGRAPDVAPEEVDESKKEDFSEADLVDVSAYSGLGEDSAGSALEEDDEDDEEDGEPPYEPESGCVEIPGLSEEEDPAPSRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQSEVAQLIQQTLEQERWQREMMEQRYAQYGEDDEETGEYATDEDEELSPTFPGGEMAIEVFELAENEDALSPVDMEPEKLVHKFKELQIKHAVTEAEIQQLKRKLQSLEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEEMDKLLDKISELEGNLQTLRNSNST
What is the function of this protein?
Seems to act as a scaffold protein in multiple signaling pathways.  Modulates excitatory synaptic transmission and dendritic spine morphology.  Binds to actin filaments (F-actin) and shows cross-linking activity.  Binds along the sides of the F-actin.  May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction.  Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors.  Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors.  May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton.  Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling.  May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins.  Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity).  Required for hepatocyte growth factor (HGF)-induced cell migration.
What are the official names of this protein?
Neurabin-2, Neurabin-II, Protein phosphatase 1 regulatory subunit 9B, Spinophilin.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Cell projection, dendritic spine. Postsynaptic density. Synapse. Cell junction, adherens junction. Cytoplasm. Cell membrane. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, ruffle membrane. Note=Enriched at synapse and cadherin-based cell-cell adhesion sites. In neurons, both cytosolic and membrane-associated, and highly enriched in the postsynaptic density apposed to exitatory synapses. Colocalizes with PPP1R2 at actin-rich adherens junctions in epithelial cells and in dendritic spines (By similarity). Accumulates in the lamellipodium, filopodium and ruffle membrane in response to hepatocyte growth factor (HGF) treatment.
Protein: RL9_ECOHS
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: Y5091_CUPNH
Sequence: MQSNHDSDASQAGDRPARPALRPLTPVEGRVLGVLVEKQHTVPDTYPLSLNALASGCNQKTARAPVMNVSEADILEAIDGLKGLSLVFEGSSSRVPRFEHNMQRVLAVPSQSVALLAMLLLRGPQTAAELRLNTARLHGFADISSVEAFLDELASHAPPFVVRLPRAPGARENRWMHLLSGEVSAAADADDADRTTGGATAAPGELEQLRAEQQALTEKVAKLQSLVEHMAGQLGIPVDEFLD
What are the official names of this protein?
UPF0502 protein H16_B1091.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.