PharMolix/UniProtQA huggingface dataset:
Protein: SAHH_SOLUE
Sequence: MGTATEKLSDATFKVADLSLAEWGRKEISVSEFEMPGLMAIRRKYAKEKPLAGVRITGSLHMTIQTAVLIETLVDLGASVRWASCNIFSTQDHAAAAIAKAGVPVFAWKGESLEEYWWCTLQAVTHPGGKGPQLVVDDGGDVTLLIHKGYELENGSDWVNTPSGSHEEKVIKDLLKQVHAEDPQRWHKMVAEWRGVSEETTTGVHRLYKMQEQGKLLVPAINVNDSVTKSKFDNLYGCRESLADGIKRATDVMVAGKVAVICGYGDVGKGSAHSLRGMGARVIVTEIDPINALQAAMEGFEVTTIEDTLGRGDIYVTCTGNCEIITLEHMRLMKDQAIVCNIGHFDNEIQMDRLNESDAKRLQIKPQVDMYTFPGGSSIFILAEGRLVNLGCATGHPSFVMSNSFANQTLAQLDLWKNKDTYKVGVYTLPKKLDEEVARLHLEKIGVKLTTLTPAQAEYLGVPVEGPYKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S18L2_HUMAN
Sequence: MSVAFVPDWLRGKAEVNQETIQRLLEENDQLIRCIVEYQNKGRGNECVQYQHVLHRNLIYLATIADASPTSTSKAME
What are the official names of this protein?
SS18-like protein 2, SYT homolog 2.
What is the protein family that this protein belongs to?
Belongs to the SS18 family.
Protein: ACCA_CLOBB
Sequence: MNKEFIKSIVVSSPWEKVEIARHKDRPTGKYYIDNIFKDFIEFHGDRLFGDDKAVIGGIASFEDISVTVIAITKGANTNENIERNFGMPNPEGYRKALRLMKQAEKFNRPVICFIDTPGAFCGVGAEERGQGSAIANNLFELSRLKTPIISIVIGEGGSGGALALTVADKILMLENAVYSILSPEGFASILWKDSKRVKEAANVMKITAQDLNEFGIIDTVIKEPRGGAHKNPQKQVTLIKKELMNAMNEMKNIETNQMINERYDKFRKIGTLE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICK38_TRILK
Sequence: MKTIIVFLSLLVLATKFGDANEGVNQEQMKEVIQNEFREDFLNEMAAMSLLQQLEAIESTLLEKEADRNSRQKRCLGENVPCGDFPCCGKLACEKTFGYGWWYKSPFCVKPSKG
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U17-barytoxin-Tl1d, U17-BATX-Tl1d, Toxin ICK-38.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 03 (ICK-30-40) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KGUA_STAAM
Sequence: MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPSLDHLRERLVGRGTESNEKIQSRINEARKEVEMMNLYDYVVVNDEVELAKNRIQCIVEAEHLKRERVEAKYRKMILEAKK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNH5_HUMAN
Sequence: MPGGKRGLVAPQNTFLENIVRRSSESSFLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKSSTCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKNRTPVWFYMQIAPIRNEHEKVVLFLCTFKDITLFKQPIEDDSTKGWTKFARLTRALTNSRSVLQQLTPMNKTEVVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKTTWDWVILILTFYTAIMVPYNVSFKTKQNNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTIQIDSWLYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVIQDDEVVAILGKGDVFGDIFWKETTLAHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDVKKEEEERLRQKNEVTLSIPVDHPVRKLFQKFKQQKELRNQGSTQGDPERNQLQVESRSLQNGASITGTSVVTVSQITPIQTSLAYVKTSESLKQNNRDAMELKPNGGADQKCLKVNSPIRMKNGNGKGWLRLKNNMGAHEEKKEDWNNVTKAESMGLLSEDPKSSDSENSVTKNPLRKTDSCDSGITKSDLRLDKAGEARSPLEHSPIQADAKHPFYPIPEQALQTTLQEVKHELKEDIQLLSCRMTALEKQVAEILKILSEKSVPQASSPKSQMPLQVPPQIPCQDIFSVSRPESPESDKDEIHF
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated potassium channel.  Elicits a non-inactivating outward rectifying current.  Channel properties may be modulated by cAMP and subunit assembly.
What are the official names of this protein?
Potassium voltage-gated channel subfamily H member 5, Ether-a-go-go potassium channel 2, hEAG2, Voltage-gated potassium channel subunit Kv10.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.2/KCNH5 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS17_PROMH
Sequence: MTDKIRTLQGRVVSDKMEKSVVVAIDRMVKHPLYGKFIRRTTKLHVHDENNECGMGDVVEIRQTRPISKTKSWALVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PUR4_VIBPA
Sequence: MRILRGSPALSEFRVNKLLELCREQDLPVTGIYAEFMHFADLKSDLDDQELEKLEKLLTYGPTIEEHEPEGLLLLVTPRPGTISPWSSKSTDIAINCGLDTVKRLERGTAYYVESSVVLSEAQVDAVKALIHDRMMETVFTELEAASALFTVAEPKPVAHVDILAGGRLALEEANVSLGLALAEDEIDYLVENFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVDQEKSLFKMIKNTFETTPDHVLSAYKDNAAVMTGSKVGRFFPDPKSRQYTYHHEDAHILMKVETHNHPTAISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWETDFGKPGRIVNALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNIRDEHVQKKEIPVGASLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERRCQEVIDRCWQLGEENPIAFIHDVGAGGISNALPELCDDGERGGKFQLRDVPNDELSMSPLEIWCNESQERYVLAVAPENMEAFDAICKRERAPYAVVGVATEERHLTLEDSHFDNTPIDMPMDILLGKTPKMHREATTLKVDSPAIARDGIEIDEAADRVLRLPTVAEKTFLITIGDRSVTGLVARDQMVGPWQVPVANCAVTAASYDTYHGEAMSMGERTPVALLDFGASARLAVGESLTNIAATDIGDIKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTKWEENGESKEVTSPLSLVITAFGRVEDVRKTVTPQLRTSDTLEGLGDTSLVLVDLGNGKNRLGATALAQVYKQLGDKPADVDNAEQLKGFFDAMQNLVRNDKLLAYHDKGDGGLFVTLAEMAFAGHCGVKADIAELGEDALAVLFNEELGAVVQVKNDDLDSVLSTLAANGLEACSHVIGSVEASDDFVFTSGDDVVLKRSRTELRVIWAETTHKMQALRDNPACADQEFEAKKDNTDPGLNVSLSFDVNEDIAAPYIAKGAKPKMAILREQGVNSHVEMAAAFDRAGFEATDIHMSDILTGQAVLDEYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFQAFFNREETFSLGVCNGCQMLSNLKELIPGADLWPRFVRNESERFEARFSLVEVQKSDSVFFDGMAGSRMPIAVSHGEGRVEVRDGEHLNAIEASGTVALRYVDNNGNPTQQYPNNPNGSPNAITGLTTADGRVTIMMPHPERVFRTVANSWAPEGWGENGAWMRMFQNARKNIG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_PSYIN
Sequence: MKTKPKSAYRRILLKLSGEALVGEEGFGIDPKVLDRMALEIKSLIEVGVQVGLVIGGGNIFRGAGLAEAGMNRVVGDHMGMLATVMNGLAMRDALQRSHVNSRLMSAIPLNGVCDDYNWAKAIRYLKQGTVVIFAAGTGNPFFTTDSAACLRGIEIEADAVLKGTKVDGVFDADPAKNPDAKLYKEIDYQLVLEKELKVMDLAAFTLARDHSLPIRVFNMNKPGALNRVVLGEDEGTTIKHCETIIEKE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESRP1_DANRE
Sequence: MTVNPDYLVLLFTTTSGASGDKLGSDEKEIVQLVWQVVDLATKKAGQVNELLVKPDHIELSEECQELSGLTDEALTPVDPLEVAIDQLNQRLCAEVDTGAGNTFYLCTDGQLHVRQVLHPEASSKNILLPDCFFSFFDLRKEFKKEFPSEVKLKDLNLQVMADHLNVAVDSSLHAFTAYKVQQMVDIVLALISEPTCHEFTFPEKVNEKFETGTCSKMERVDDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHMGGRYIEVYKATGEDFLKIAGGTSNEVASFLSRENQIIVRMRGLPFNATAEQVLQFFSPACPVTDGSEGILFVRFPDGRPTGDAFVLFSCEEHAQNALKKHKDMLGKRYIELFKSTAAEVQQVLNKYSSAPLIPVAPSPILSVVAPPTFVPQTAAVPGVRDCVRLRGLPYDASIQDILVFLGEYGADIKTHGVHMVLNHQGRPSGEAFIQMRSAERAFLAAQRCHKRSMKERYVEVFACSAQEVNIVLMGGTLNRSGLSPPPCLSPPSYTFPHGAPVLPAGAVLPAGAVLPVESAGIYPSQFLLGPRPPPHTTTFYPASNTLYMNYTTYYPSPPGSPSNISYFPTGHTPSAGSVLSAQPTALIRMQGHAHSHAYNNGVKEILSMVQGYQPGNSDAFVTFPSMLSAKQPIGDQTVGGGAYLDLQLL
What is the function of this protein?
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms.  Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of fgfr2.  Acts by directly binding specific sequences in mRNAs.  Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of fgfr2 (By similarity).
What are the official names of this protein?
Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A.
What is the protein family that this protein belongs to?
Belongs to the ESRP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHEB2_CUPPJ
Sequence: MTAAKIKVLCVDDSALIRSLMTEIINSQPDMEVVGTAPDPLVAREMIKQLNPDVLTLDVEMPRMDGLDFLERLMRLRPMPVLMVSSLTERGSEITMRALELGAVDFVTKPKLGIRDGLMEYTDTIADKIRAASRARVRQAPQAASGTPATPMLRSPLLSTEKLIILGASTGGTEAIKDFLMPLPPDSPAVLIVQHMPAGFTRSFAQRLDGLCRITVKEAEHGERVLPGYAYIAPGDSHLRLARSGANYVAHLSQEAPVNRHRPSVDVLFDSAAEHGGKNVIGVILTGMGKDGAKGMLRMREAGAYNLAQDESTCIVFGMPKEAIAAGGVHEVVPLHSMTQRVMARLATYGTRAQRV
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S61A1_CANLF
Sequence: MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCHYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER) (PubMed:10799540, PubMed:1423609).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides (By similarity).  May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins (By similarity).  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex (PubMed:36261528).  The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER (By similarity).  Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC61 channel, contributing to the maintenance of cellular calcium homeostasis (By similarity).  Plays a critical role in nephrogenesis, specifically at pronephros stage (By similarity).
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha isoform 1, Sec61 alpha-1.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Protein: RL15_PSE14
Sequence: MKLNDLSPAPGSRREKHRPGRGIGSGLGKTGGRGHKGQSSRSGGTIAPGFEGGQQPLHRRLPKFGFVSLKAMDRAEVRLSELAKVEGDIVTVQSLKDANVINQNVQRVKIMLSGEVTRAVTIKGIAATKGARAAIEAAGGKFEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: THEM6_DROME
Sequence: MSWLVVLLILYVIWDVNYFIRCVFTVFAGRLFQRKRKVTDTTTIYGLCTSQDVDIFIRHMNNARYLRELDFARFHFYALTGLYERIRDRRGGAVQGASSVRYRRTIPIFHPYKIQTKLIWWDDKAIYLEQQFITLSDGFVRAVAMSKQNITNCNVLEVLKTYPETAQRPEKPEELKLWLDAIELSSQKLRKDK
What are the official names of this protein?
Protein THEM6.
What is the protein family that this protein belongs to?
Belongs to the THEM6 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FM3_BORPE
Sequence: MSKFSYPALRAALILAASPVLPALANDGTIVITGSISDQTCVIEEPSTLNHIKVVQLPKISKNALRNDGDTAGATPFDIKLKECPQALGALKLYFEPGITTNYDTGDLIAYKQTYNASGNGNLSTVSSATKAKGVEFRLANLNGQHIRMGTDKTTQAAQTFTGKVTNGSKSYTLRYLASYVKKPKEDVDAAQITSYVGFSVVYP
What is the function of this protein?
Bordetella pertussis is the causative agent of whooping cough.  An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms.  It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B. pertussis are prime candidates for being involved in this process.
What are the official names of this protein?
Serotype 3 fimbrial subunit.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium. Note=Pili structure on the cell surface.
Protein: APC1_MOUSE
Sequence: MSNFSEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSTVQQALWCDFIISQDKSEKIYKSHELEKCICILQSSCMNMHSIDGKDYIASLPFQVANVWATKYGLLFERCSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEENAVLKFPEQAGTLQNATTSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGAQRFNLSSHSQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLPNIREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIHTMLVLEGNGNLVLYTGVVRVGKVFIPGLPAPSLTMSNMMPRPSTPLDGVGTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIHSVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAIQVLVKWYNVHSAPGGPSCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDEDWEYLLNSEYHRNVESHLLNKSLCLTALEVSNAKDEDFSQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLDSYLDHYYRDSPTLVKTTGQVCTIDQGQMGFMHHPPFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETCQYLSKVTSTPQKPQAEQEENRFTFRHSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPRGKSVLSSEVSSGTEAEEEDDGMNDLNHEVMSLIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPVPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFSCLHKFAKDFMNYLSAPNASVTGPYNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGPKQEILDLFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSDTSDLWQIKLILEFFSSRSHQDRQHTYPKRGLFINSEFLPVVKCTVDATLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPMGLEGSTSFAELLYRFRHLKMPVRALLRLAPVLLGNPQPMVM
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 1, APC1, Cyclosome subunit 1, Mitotic checkpoint regulator, Testis-specific gene 24 protein.
What is the protein family that this protein belongs to?
Belongs to the APC1 family.
Protein: RDRP_HV19S
Sequence: MSDPQERSKAYGLLGERLYAVASANSHMLAGYDSLDFTARLVRLTGEATALKAVDPLLPCAVSLLFMDFPLQLPCTPEETLRLVRRAYDPNTLEEVDYSTLSGYATQFARVKGQRGRWRHLGHLVCNDKAFRERYFPKKKHAAAAIKTNIRLGPLARAWAARYGLAALGSHLAYMVGMPNDRACATLLLAQTYKARFGSEGVAWAIASVRQPENAKGLSNALKALGSNTSEPGALFVEANTLQGRYDRTLDMDHEVESRCSPAAIADQVIPYTDELGACIDFILDTELGGDTIELPDEDEWWTSRWLWCVNGSQNALSDKALGIKNKSGQRYRRMAAEEVNNNPVPAWNGHTSVSPSVKLENGKDRAIFACDTRSYFAFTYWLTPIEKKWRGARVILNPGEGGLYGTARRIRGSQTSGGVNLMLDYDNFNSQHSNETMAALYEKALSRTNAPAYLKKAVAASVESTYIHYKGRDRHVLGTLMSGHRATTFTNSVLNAAYICYAVGIPAFKRMISLHAGDDVYLRLPTLADCATTLNNTKRVGCRMNPTKQSIGYTGAEFLRLGINKSYAIGYLCRAIASLVSGSWTSLDELQPLNALNGAIVQTRSCLNRGAATGLPELISASFVGLRGFKRRDLLELLTGVATIKPGPVYTSSCVIREYVVEQPPPPQFDVPPGAGMHATMSYLARHTTLVEAQALEIARPAIKSLMLSSSYGKAGPGAQTRPHVPMPKLRRQPPRVAVGFSMAHELTGRGVKEGCLSGHPLLRLFEQRLTDDDLRALVALVGGNTSAKDIRAEAFGAESSSSTIMGILPHSDASNYCKRTRNGNIIVPYHIRS
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome.  Catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded from the virion into the cytoplasm where they function as mRNAs for translation of viral proteins and also as substrates for encapsidation to form new virions.  Once encapsidated, the positive strand is converted to dsRNA by the RNA-directed RNA polymerase (By similarity).
What are the official names of this protein?
Probable RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the totiviridae RNA-directed RNA polymerase family.
Protein: TULP1_HUMAN
Sequence: MPLRDETLREVWASDSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCPTGSKPRKPGAGRTGRPREEPSPDPAQARAPQTVYARFLRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKTKKKGSGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKAKEERAPSPPVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMYPSYFLHLDTEKKVFLLAGRKRKRSKTANYLISIDPTNLSRGGENFIGKLRSNLLGNRFTVFDNGQNPQRGYSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFDGKLACE
What is the function of this protein?
Required for normal development of photoreceptor synapses.  Required for normal photoreceptor function and for long-term survival of photoreceptor cells.  Interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells (By similarity).  Binds lipids, especially phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro).  Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.
What are the official names of this protein?
Tubby-related protein 1, Tubby-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Secreted. Synapse. Note=Detected at synapses between photoreceptor cells and second-order neurons. Does not have a cleavable signal peptide and is secreted by an alternative pathway (By similarity).
Protein: XYNA_THEAU
Sequence: MVRPTILLTSLLLAPFAAASPILEERQAAQSVDQLIKARGKVYFGVATDQNRLTTGKNAAIIQADFGQVTPENSMKWDATEPSQGNFNFAGADYLVNWAQQNGKLIRGHTLVWHSQLPSWVSSITDKNTLTNVMKNHITTLMTRYKGKIRAWDVVNEAFNEDGSLRQTVFLNVIGEDYIPIAFQTARAADPNAKLYINDYNLDSASYPKTQAIVNRVKQWRAAGVPIDGIGSQTHLSAGQGAGVLQALPLLASAGTPEVAITELDVAGASPTDYVNVVNACLNVQSCVGITVWGVADPDSWRASTTPLLFDGNFNPKPAYNAIVQDLQQ
What are the official names of this protein?
Endo-1,4-beta-xylanase, Xylanase, 1,4-beta-D-xylan xylanohydrolase, TAXI.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
Protein: YFAL_ECOLI
Sequence: MRIIFLRKEYLSLLPSMIASLFSANGVAAVTDSCQGYDVKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNAMFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIVNNTAFTNNTAEGYGGAIYTNSVTAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQNQAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGIIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAADLTALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITSDVDTRSDAAGHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADILPYASSLWVGDGATFVTGADQDIQSIDAISSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFSNDVSEQEDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
What is the function of this protein?
Probably an autotransporter.
What are the official names of this protein?
Probable autotransporter YfaL.
What are the subcellular locations of this protein?
[Probable autotransporter YfaL]: Periplasm. SUBCELLULAR LOCATION: [Probable secreted autotransporter protein YfaL]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Probable autotransporter YfaL translocator]: Cell outer membrane.
Protein: EMBA_MYCTU
Sequence: MPHDGNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIATLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAGTLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGALKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRYRPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTAGVWMRLPATLAGIACWLIVSRFVLRRLGPGPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSIALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAALSLITVVVFRDQTLATVAESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGLLLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPVIASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAKANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPNKPNAAITDSAGTAGGKGPVGINGSHAALPFGLDPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSYKEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFPIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPRVPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTSTIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP
What is the function of this protein?
Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
What are the official names of this protein?
Probable arabinosyltransferase A.
What is the protein family that this protein belongs to?
Belongs to the emb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.