PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_SALPK
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLDDEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: Y422_LACGA
Sequence: MSSLDKTMHFDFNQNKGKNVYDTLQDVYNALEEKGYSPINQIVGYLLSGDPAYIPRHNDARNLILKHERDEIIEELVKSYLGKNK
What are the official names of this protein?
UPF0297 protein LGAS_0422.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: CRED_ASPFU
Sequence: MALSFFGGGGASHLKYFDIRLDEDYIVFRGGEQEAASAQLSGKLLLCLSEPLSVKHVRLNLTGISRVCWHLPSSSATGGRKSWREKVFYEKSWTFRDAGKSKTEILAAGNYEFPFHVILEGSMPESVEGLSDTYVTYRFKAEIGRKYAKDIVVRKPLRIIRTLDSSALELSHAMSVENIWPNKIEYSISTPTKAVIFGTSIRVDFKLIPLLKGLKIGQIVSQLIESHDLTLNPEDPDSVRNTYKNTRTIVNDEHELDEEGNLEIIDEAAEGYQFSRFLDLPKTLTRCLQDTDTRGIKIRHKLKFRVQLLNPDGHISELRATLPVSIFISPNLAIDDNNNLVDQTPQSAQRAVNDLAQQAPPLYGEHQFDQLYSEVDPSGYRTPGPGSGPGTPFGTLSRNLSAENLASMNALTNTDISASALHSRLSNLHASRFSNPSPSDADGHTDAEYRRLGVSTDSFGPSSGSNSQSPASPELSRRPSDEGYHDHDYIPSGMATPFHPQFAEVESLSRVPSYSTAVRSSVGPCDSELPDYQAVVAEDTAMPTLQSPQQAHIRSVGRGVSTGHTGIDVHHLRSGFFNSRTSAHHDDDDRRLRLVQARARV
What is the function of this protein?
Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability (By similarity).
What are the official names of this protein?
Probable HECT-type ubiquitin ligase-interacting protein creD, Carbon catabolite repressor D.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: TRUA_STRPB
Sequence: MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKIIIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHCRYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAAGTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQVKVILSSKNRQLAGPTISGNGLYLKEICYEN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: DMXR9_CRYX8
Sequence: MAPSTIGTNVAGDKYEYDPENWMAKGTSTLNNGNGTKGTLDVDLPERHPETGINVLVVGAGMGGLMTTLECWRKGHNIVGILERNDGPVYSGDIIVIQPSAVSVLRHWPDMMRDMEDEQVNAAVSYEQHTGRHIYGPTVPSFNELEHLASRKGPFVAPAQIREKFYRMLLRQVAKLGFKVQYGKRAVSYFEDIAAGKGGVVLESGEIQVADVVVAADGLRSTSEILIAGEHTPTKSSGMSIYRTAYPREMAMKDETVRKRWADTKEIWEYWLGPGMYIGVFFSEDVVSWGFTPRDTHGGATESWEPDTDPEDVVKELLRVPDWDPAIAALVRTAPKGAIVHWPLLWRNLRREWTSSGGHVVQLGDSAHSFVPTSGNGATQALEDAITLATCLQLGGAARNAPLATKIYNLLRYERVSCAQKMSFVNSQLKTETDWDGIWADPIKVRTRFPKWIHNHDPEDYAYAKYGQAFAHLVAGADFANENFPPGHHFVPWSIEEVYADIEAGKKVEALLDGDWS
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the dimeric xanthones cryptosporioptides (PubMed:30996871).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase dmx-nrPKS (Probable).  The atrochrysone carboxyl ACP thioesterase dmxR1 then breaks the thioester bond and releases the atrochrysone carboxylic acid from dmx-nrPKS (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase dmxR15, and oxidized by the anthrone oxygenase dmxR16 to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by the oxidoreductase dmxR7 (Probable).  A-ring reduction by the short chain dehydrogenase dmxR18, dehydration by the scytalone dehydratase-like protein dmxR17 and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:30996871).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) dmxR6 then yields monodictylactone in equilibrium with monodictyphenone (PubMed:30996871).  In the case of the cryptosporioptides biosynthesis, monodictylactone is reduced at C-12 to an alcohol (by the short chain dehydrogenases dmxR12 or dmxR8) and hydroxylated at C-5 by dmxR9, yielding the electron-rich aromatic which could eliminate H(2)O to form the ortho-quinonemethide, followed by tautomerisation to paraquinone and complete the formal reduction to produce the 10-methylgroup (Probable).  Conjugate addition of C-4a-OH to the resulting paraquinone by the monooxygenase dmxR10 then gives cyclohexadienone, which is then reduced at C-5 by the short chain dehydrogenase dmxR3 to give the dihydroxanthone (Probable).  The 6,7-epoxide in the cryptosporioptides could be introduced by the cytochrome P450 monooxygenase dmxL3 (Probable).  The highly reducing PKS dmxL2 manufactures butyrate, which is further carboxylated by dmxL1 to form ethylmalonate (PubMed:30996871).  It is not yet clear whether the carboxylation occurs while the butyrate is attached to the ACP of dmxL2, but this unusual fungal metabolite could then be esterified to O-5 by the O-acetyltransferase dmxR13 (PubMed:30996871).  Finally, dimerization performed by dmxR5 gives the observed dimers cryptosporioptides A, B and C as the final products of the pathway (PubMed:30996871).
What are the official names of this protein?
FAD-dependent monooxygenase dmxR9, FMO dmxR9, Dimeric xanthone biosynthesis cluster protein R9.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: MLTF_SHESA
Sequence: MTRFLFAIILGFLLTACQQVTVEETEYVPHKLTELRVGTLYGPQIYMTSGQGNSGFDYDMAVLFAEYLDVPLKMVPYTNRAELYDALKKNEIDIIAAGMTETPARREQFRLGPPLYRVNQVLVYREGMPTPKDITDLKGKITVIADSSFVETLTQLQKRHPTLVWDQVTDKDSEELLAMIANKEIDYTIADSSSVQINRRYLPDLRSGLVLEEKLDVVWLLPPTHSDGLMSQLLAFWHQEKLAGTLDHLNEKYFGHVKRFDYIDTRAFLRAIETVLPRYRQLFETHAGDLDWRKLAATSYQESHWNPNARSPTGVRGMMMLTQPTAKEIGITNRLDAEESIRGGAAYLRDMINRLPESIPESQRMWFALASYNIGYAHVEDARKLAESMELNPNAWRDLKKVLPLLQKRKYYQKTRYGYARGSEAVHYVDSIRRYYDTLVWVDNQSKQQNSDEEEPSDLASEDGPAPVPGTLSPDKPK
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: RL6_BACAN
Sequence: MSRIGKKILEIPAGVTITVAEDNTVTVKGPKGELTRTFNADMLIKIEENTLTVERPSEQKEHRALHGTTRALIGNMVEGVTEGFARGLELVGVGYRAQKQGDKLVLSVGYSHPVEMTPEAGLEVEVPAPTKIVIKGIDKQRVGEFAANIRAVRAPEPYKGKGIRYEGEVVRRKEGKTAK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RF1_PERMH
Sequence: MLNKYLLQKLENIDEKLKKLEAALSDPEVLKDQKKLQQVAKEHKETEKLSKLYKEYKKVLKDIEETKSLLNNPDEEMRLLAEEELKNLNQRKEELEKEIQIELLPKDPNDEKNVILEIRQGAGGEEAALFAGELFRMYQRYAERKGWKVEVLSMHPTDRGGIKEVIALIKGQGAYSRLKFESGVHRVQRVPETESSGRIHTSTATVAVLPEAEEVDIEIKPEELKIETMRASGAGGQHVNTTDSAVRITHIPTGIVVSCQDERSQLQNRAKAMQILRARLKDYYDRLEREKIEKERRMQVGTGDRSEKIRTYNFPQNRVTDHRINYTSHRLHDILDGDLDEIIDQLIAKEQEQKLLAISEE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKB_ESCF3
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQVRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEAFSSSQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFTPQLPETLPGTVDAPSEAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: Y1407_MYCTU
Sequence: MTPRSRGPRRRPLDPARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCRARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTVEQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVHAHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELARAVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAPVDGDTGRWLDLCAGPGGKTALLAGLGLQCAARVTAVEPSPHRADLVAQNTRGLPVELLRVDGRHTDLDPGFDRVLVDAPCTGLGALRRRPEARWRRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADALRRHPVHALDTRPLFEPVIAGLGEGPHVQLWPHRHGTDAMFAAALRRLT
What is the function of this protein?
May act as RNA methyltransferase.
What are the official names of this protein?
Putative methyltransferase Rv1407.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
Protein: AAEX_ECO57
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVCRVLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: STKLR_ARATH
Sequence: MAPKQLKKIENPVVSSSEEEESASSGESATSGEESDSSADSPVKESSKKPVVVSKPSGSKTTTKPESSTAAKRSFEKTDEMSKKKSKNSMGEEDVKKKDETLKKNLFVRLFTEEDEAILLQGFLDFATKKENPSDHIDDFYESIKNSISFDVTKPQLVTKIGNLKKKFNGRVSKGLKKGKNEEVMVFSKASDQNCFDLSRKIWGSNGVLYSKSKNMRQVQLGGSVKVDEDDQEPQKHRFVISTLSSGQELVSYLKVENPNSLGVDDTKWSAKLDKIKDGKQKRKMEKNLKKIQAKEEELSMMRSEFVAAVTNVLSKQDNASYSCK
What are the official names of this protein?
Probable transcription factor At4g01260, Storekeeper-like protein At4g01260.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
Protein: PURL_BRADU
Sequence: MKNEPKITPELVAAHGLKPDEYERILKLIGREPTFTELGIFSAMWNEHCSYKSSRIHLRGLPTKAPWVIQGPGENAGVIDIGDGQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARPIACLNALSFGAPEHAKTRHLVSGVVAGVGGYGNSFGVPTVGGQVRFHTRYDGNILVNAMAVGLADADKIFYAAASGVNMPIVYLGSKTGRDGIHGASMASAEFDDKSEEKRPTVQVGDPFAEKLLLEACLEIMEKGCVIAIQDMGAAGLTCSAVEMGAKGDLGVDLDLDAVPTRETGMSAYEMMLSESQERMLMVLKPEKEKEAEAIFKKWGLDFAVVGYTTPSKRFVVKHGGDVMADLPIKELGDEAPLYDRPHVPSAALPVVHAREVMAPMGVGSALEKLIGTPDMCSKRWVWEQYDHVILGNTMQRPGGDAAVVRVQDGPKGLALTVDVTPRYCEADPFEGGKQAVAEAWRNITAVGGKPLAITDNLNFGNPERPEIMGQFVGCLKGISEACRTLDFPVVSGNVSLYNETNGRAILPTPSIGGVGLLDDFTKSASLAFKAEGEAILLIGETHGWLGQSVYLRDICGREEGAPPPVDLAAEKRNGDCVRGMIHAGTATAVHDLSDGGLLIALAEMAMASGIGAKLLAAPTSLVSQAYWFGEDQARYLVTVPETEAGRVLAKMRGCEVPCVRIGTTGGDAIAIAGEAPVTIDKLRTSFERWLPEYMGGKAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_MYCS2
Sequence: MTAPNHPPGRTRVAVVYGGRSSEHAISCVSAGSILRNLDPERFEVVAIGITPDGSWVLTDGRPETLAITDGKLPAVTEASGTELALPAAPNRSGQLLALGNGPGEILAAVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGSGVLASAAGMDKEYTKKLLAAEGLPIGDQVVLRPGVETLDLEQRERLGLPVFVKPARGGSSIGVSRVTAWDELPAAVALARRHDPKVIVEAAVIGRELECGVLEFPDGRLEASTVGEIRVAGVRGREDGFYDFATKYLEDAAELDVPAKVDDDVADEIRQLAVRAFTAIGCQGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAAGGIDYPTLLAAMVDTAIARGTGLR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_SALDC
Sequence: MSLTRLLIKDFRNIENADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQPGRVIRHEQEAFVLHGRLQGEERETSIGLTKDKQGDSKVRIDGTDGHKIAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEAGFFTAWSNLKRLLKQRNAALRQVSRYEQLRPWDKELIPLAEQISTWRAEYSSAIAQDMADTCQQFLPEFSLTFSFQRGWEKETDYADVLERSFERDRMLTYTAHGPHKADFRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDARRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CAMHC
Sequence: MIQSFTRLAVADNSGAKELMCIKILGGSKRRYATVGDIIVCSVKKALPNGKIKRGQVVKAVVVRTKKELHRGNGSLIRFDENAAVVLDSKKELIGTRIFGPVGREVRYNGFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RNPS1_BOVIN
Sequence: MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPLPMWRRSPPRMRRRSRSPRRRSPARRRSRSPGRRRHRSRSSSNSSR
What is the function of this protein?
Part of pre- and post-splicing multiprotein mRNP complexes.  Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets.  The ASAP complex can inhibit RNA processing during in vitro splicing reactions.  The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis.  Enhances the formation of the ATP-dependent A complex of the spliceosome.  Involved in both constitutive splicing and, in association with SRP54 and TRA2B/SFRS10, in distinctive modulation of alternative splicing in a substrate-dependent manner.  Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function.  Participates in mRNA 3'-end cleavage.  Involved in UPF2-dependent nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Also mediates increase of mRNA abundance and translational efficiency.  Binds spliced mRNA 20-25 nt upstream of exon-exon junctions (By similarity).
What are the official names of this protein?
RNA-binding protein with serine-rich domain 1.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles (By similarity).
Protein: SLK_RAT
Sequence: MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPVRELIAEAKAEVTEEVEDGKEEDDDDETESALPIPANKRASSDLSIASSEEDKLSQNACILESVSERTEHNTSGDKFSNKVLSEKPTPEGPEKTVDVDGPANDVNLETVAEPNDQAVGFHENGREKKRPQLESQPDTEDQQTVDVNLVGEGNDSNIVILETNTDCLKPEEDRNEENQEIIENKLTQSEEIKDIHIQTMDLVSQETGEKEADFQAIDNEVGFTKEETQEKLGKDDKTHKVVISDITSEVGTDEPPGDTQKSAEQSQDAEGGAGEEAPEPAQTLTEKATEGPEAHGAEEEPRSGERVEDKQLEQQSAVCEGEGQVTSTSESTRATTEEPETDEVDQVSESNSIEELERLGVTGAEEQALGSKGEAATELDLEREENAQELPVKAEPQAPAASQASEPPPVLIPSINIHSENTENKGEMGALPKPETILPPEPENGKGNDTDSGTGSTVENSSSDLNLSISSFLSKTKDSGSVSLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRLLQKEEQKAQQQLNGKLQQQREQIFRRFEQEMLSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLRNRKKEEQEFVQKQQQELDGALKKIIQQQKAELANIERECLNNKQQLLRAREAAIWELEERHLQEKHQLLKQQLKDQYFIQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDREKIKQFAAQEEKRQKNERMAQHQKHESQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSAQSRGCLQTSHPSSTRAPAWAG
What is the function of this protein?
Mediates apoptosis and actin stress fiber dissolution.
What are the official names of this protein?
STE20-like serine/threonine-protein kinase, STE20-like kinase, STE20-related serine/threonine-protein kinase, STE20-related kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAM17_ASHGO
Sequence: MLARGILRPALARAELGRAFSCSAQWQQAAGSTSGRELSWPDFFALRKTERRINTGSSVLTAFLTANCAWAYISTVQIDVTQMLFGFDPMVVLVGALFASSGLGYLCGPLMGSAFFRVKHRGQLEGYNHKNRVFLEHIKKNRVDASSQSFSNPLPDYYGEKIGSLQEYRQWLRDCQSHRRKAKEFL
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Presequence translocated-associated motor subunit PAM17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MDH_PROA2
Sequence: MKITVIGAGHVGATAAHRIAEMQLAKEVVLLDIVEGIPQGKALDMYESGPIGLFDSKIYGTNDYQDTADSDIILITAGMARKPGMSREDLLLKNATIVKEVTDRIMQYSSNPIIIMVSNPLDIMTYVSYVRSKLPKERVIGMAGVLDSARFRSFIAEELNVSMKDINAFVLGGHGDSMVPVVKYTNIAGIPLTELLSQEKIDSLVDRTRKGGAEIVNYLKDGSAYYAPAASAVEMIDAIVHDRKRILPCSTLVTGQYGMDNVFIGVPVKIGKNGIEEVLEINLDTAELEALRQSASIVESNCSNLADLLS
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.