PharMolix/UniProtQA huggingface dataset:
Protein: SLX4_AJEDR
Sequence: MDNAAIASQSNTPPSNGRSSARFVTPISVHSSPITAEVIEPSSPFSPPSPSTLLTSLSKSPSHKISNLQMDGAKTTCLEVLQNSSLVVDSPKRQDKSITGSKAKPASTMRHGQRTASHKMATQTEIQTVDGDRLIVSPKTRKKKAATAKRTRKQDGVAERRLHGHVSKVKSPGDLKLDAKIPPSKPCDNKAPSVGDNTDNELERQTGGLQLEKATKRRLDWTPTKEGPIPMVDLAEVHSSSCGKSVIRTHSAGTLLSNYGFSGVVNTSLAPMPETCDNGPTTKRLMELQNFYSASGIQTPTESRPATNDSQSISSKQQRVKVKKPQKAKLTTLTSYVTAKYSVVDQTADLDRIETVNSGKNKKMGVTKRTSGTERANAARGKSDTLKNGNGPPVFKVVPPLEAFKSFDGQELLFGTSSQLEHGHSEDQDEEIQHTADSINKSNVVPRPAVSKGLGSSLFRLSSSKNLWSASSRDLTGAVLQVDEIDLSERSIEVSTPAAKYKRKTGIRDLSGQNVIDVEKDTRTLAANIDTRELDNMNEPSLAEDDLVYRENLESTNAKLNSQTPANISEAMLERPLPDKPIFGGFTTSELAKQVAAYGFKPIKSRDKMISLLEKCWENQSKSSKLEPKPNQRNHKSQGDDLAERQLLGLKPRSDSISFVNTRSPKKRLAKTSVKSQESKSFSLSNEGPRITSKLPMKRFVSPCAILIDDDQSSDSVGEALPLSPSHSSNGNGTLHHPQDCDEIHAPTTQMAIRSAKSSISVSSTTNLPSLSSQITKAVQSQPRIRAFKGLKQPTWYEKILMYDPIQLEDLAAWLNTGGFGLIGEDREVGAGVVREWCESKGICCVWKKQASAKSH
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y358_RICPR
Sequence: MQYLILSLIFLIPSLGMLTGLSIAATVAFFLLSIIITGFISFIQKQEFNKKFFIKLYPRFGFDDIFCIINKIKTELLFTAWCFISCLFAVHPINSLVTFTKVFVLLFLRFVSNAVTFQNVLYIKNSLILGIITAILLFFIEYSSHGFLTRMFKTHFGLYMLDRGCALLSITTWVAIIILFSNGHNINSFILYIVVLYLLSISDSLASFLGFSIGGIIFILARLIKTIFFKLITISLITGSLLFPVIAKQIDPQNLSEKYLATQPSAAHRLFIWHFVANKIIIRPILGYGFASSKYIETGDNAMIDYRGEKLHPLPLHPHNNILQITLELGILGLALFLCLVYKYLKEIDNIKVSNFRAASYSCFINYYIIGMISYNIWQTWWILSGIWILVLMKLLVKPDIIIDN
What are the official names of this protein?
Putative polysaccharide polymerase RP358.
What is the protein family that this protein belongs to?
Belongs to the O-antigen polymerase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYRC_PSEMY
Sequence: MSDRLTLLRPDDWHIHLRDGAVLPHTVGDAARTFGRAIIMPNLVPPVRNAAEADAYRQRILAARPAGSRFEPLMVLYLTDNTSPEDVRAAKASGFVHAAKLYPAGATTNSDSGVTSIDKIFPALEAMAEVGMLLLVHGEVTRAEIDVFDREKAFIDEHLTRVVERFPTLKVVFEHITTRDAVQFVEAASANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNVHQEALLDAATSGNVKFFLGTDSAPHAKHAKEAACGCAGCYTAFAAIELYAEAFEQRNALDKLEAFASFHGPDFYGLPRNTDSITLVREEWTVPASLPLGENSVVPLRAGETLRWKLLEGQA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: NIKB_STAAW
Sequence: MFIIKSMLYRLMQMIVVLFVISTLTFILMKLSPGNPVDKILHLDVAQVSTEQINATKDKLGLNDSLLVQWWHWMNHLLHFNLGKSFESKEPVTQILFNYAPITLLISFSTLVVSLCISIPLGIIAAKRFHKWTDKVIRVISTLSISLPAFFIGIILLFIVTNLMNIDSVILSQFILPVITLSLGMCAYIIRLVRSNLLMLLQSNIVQASRLRGMNERYILIHDLLKPTILPIIPLLGISLGSLIGGTVVIENLFDIPGIGYLLMDSIKSRDYPVIQGCVLFIGFFVVIINTIADLLTLLLDPKQRLQLGNPKIKTNTPLISVSSDRHA
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Nickel import system permease protein NikB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBA5_HUMAN
Sequence: MAESVERLQQRVQELERELAQERSLQVPRSGDGGGGRVRIEKMSSEVVDSNPYSRLMALKRMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVAANIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMKPNPQCDDRNCRKQQEEYKKKVAALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKNFSGPVPDLPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMAKMKNM
What is the function of this protein?
E1-like enzyme which specifically catalyzes the first step in ufmylation (PubMed:15071506, PubMed:18442052, PubMed:25219498, PubMed:20368332, PubMed:27653677, PubMed:26929408, PubMed:27545674, PubMed:30412706, PubMed:27545681).  Activates UFM1 by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a UFM1-E1 thioester and free AMP (PubMed:20368332, PubMed:27653677, PubMed:26929408, PubMed:30412706).  Activates UFM1 via a trans-binding mechanism, in which UFM1 interacts with distinct sites in both subunits of the UBA5 homodimer (PubMed:27653677).  Trans-binding also promotes stabilization of the UBA5 homodimer, and enhances ATP-binding (PubMed:29295865).  Transfer of UFM1 from UBA5 to the E2-like enzyme UFC1 also takes place using a trans mechanism (PubMed:27653677).  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (PubMed:32160526).  Ufmylation is essential for erythroid differentiation of both megakaryocytes and erythrocytes (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5, ThiFP1, UFM1-activating enzyme, Ubiquitin-activating enzyme E1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Golgi apparatus. Note=Localizes mainly in the cytoplasm, while it localizes to the nucleus in presence of SUMO2 (PubMed:18442052). Interaction with GABARAPL2 promotes localization to the endoplasmic reticulum membrane (PubMed:30990354).
Protein: TBB2_CHICK
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEGEEDEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2 chain, Beta-tubulin class-II.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DLTA_STAHJ
Sequence: MTDIINLINDFGQSNPERVAVRHKDEELTYQQLMDESSKLAHLLQDNHKPLIVYGHMSPYMLVGMIGAIKAGCGYVPIDTSVPSERVNMIINKVQPDIIFNTSDTQLNHSNIQELTIQSIQDSDNPTLFDSQMGLTDVVYTIFTSGSTGEPKGVQIEYASLIEFAEWMVSLNESEGSQEWLNQAPFSFDLSVMAIYPCLTSGGTLNLVDKEMINKPKLLNEMLVNTPINAWVSTPSFMEMCLLLPNLNESSYPSLNHFFFCGEILPHRTAKALLDRYPSAVVYNTYGPTEATVAVTGIKLTPEVIEAYNPLPVGVSRPNTSLFTTDEGELVIKGNSVSLGYLDNKEKTDAVFNFEDGLRIYHTGDKAIEKDGQWFIQGRIDFQIKLNGYRMELEEIETQLRQSEFVRETVVVPVYKNNKVIHLIGAVVPTEEVRDDLEMTRQIKSELKSRLPEYMIPRKFVWMKQLPLTSNGKLDRKQVAEDINA
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCAD_ECO24
Sequence: MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVGVVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRFVAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSVLPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITAMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVILGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y772_STAAB
Sequence: MADESKFEQAKGNVKETIGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
What are the official names of this protein?
UPF0337 protein SAB0772.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: AAAT_HUMAN
Sequence: MVADPPRDSKGLAAAEPTANGGLALASIEDQGAAAGGYCGSRDQVRRCLRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPELIQVKSELPLDPLPVPTEEGNPLLKHYRGPAGDATVASEKESVM
What is the function of this protein?
(Microbial infection) Acts as a cell surface receptor for type D simian retroviruses.
What are the official names of this protein?
Neutral amino acid transporter B(0), ATB(0), Baboon M7 virus receptor, RD114/simian type D retrovirus receptor, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: FIBB_RANTA
Sequence: QHLADYDEVEDDRAKLHLDAR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: PSB1_PYRAR
Sequence: MTTTVGIVVKDGVVLATDKRVTAGYYIAHKKGEKLWKIDDHVAATMSGGVADLQNILSFLTVRAREYKTQFRRPIPIRALVNYMSLILFYSRPYVYVVHSIIGGVDEEEGAVMYMVDWLGTVTKEKYVATGSGSPYAKGVLEVGYRGDLTVEEAVDLAINAIKAAIRNDPGSGEGIDVVTITKRDGFKRIFTTQQKLLIPEI
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PsmB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPDR1_MOUSE
Sequence: MPARAPRRLVQGPRGTWLLGSLWVWVLCGLGMAGSLGTPQPCQAPQQWEGRQVLYQQSSGHNNRALVSYDGLNQRVRVLDERKALIPCKRLFEYILLYKEGVMFQIEQATKQCAKIPLVESWDPLDIPQNSTFEDQYSIGGPQEQILVQEWSDRRTARSYETWIGVYTAKDCYPVQETFIRNYTVVMSTRFFDVQLGIKDPSVFTPPSTCQAAQPEKMSDGCSL
What is the function of this protein?
Binds anionic lipids and gangliosides at acidic pH.
What are the official names of this protein?
Mammalian ependymin-related protein 1, MERP-1.
What is the protein family that this protein belongs to?
Belongs to the ependymin family.
What are the subcellular locations of this protein?
Lysosome lumen. Secreted. Note=Lysosomal and also secreted.
Protein: LRAT2_HUMAN
Sequence: MGNQVEKLTHLSYKEVPTADPTGVDRDDGPRIGVSYIFSNDDEDVEPQPPPQGPDGGGLPDGGDGPPPPQPQPYDPRLHEVECSVFYRDECIYQKSFAPGSAALSTYTPENLLNKCKPGDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVINSFLTDASQGRRGRVVNDLYRYKPLSSSAVVRNALAHVGAKERELSWRNSESFAAWCRYGKREFKIGGELRIGKQPYRLQIQLSAQRSHTLEFQSLEDLIMEKRRNDQIGRAAVLQELATHLHPAEPEEGDSNVARTTPPPGRPPAPSSEEEDGEAVAH
What are the official names of this protein?
Protein LRATD2, Breast cancer membrane protein 101, LRAT domain-containing 2, Protein FAM84B, Protein NSE2.
What is the protein family that this protein belongs to?
Belongs to the LRATD family.
Protein: ARNR_SULAC
Sequence: MTKSLFDVLKELDSLVDFSRAKLQWDILIILATKGPSSTTEISQTINTSRKSIIDAIRKLVDKELVTKVKHDIYGLSDKGKELWNKIDSVLNIEVINGNNHKGQSKDEDILALENLSQYFYLINLSKMITINHDGLSLDKAARELGVSRQTLKYYLELFEEKKLFRVIGKRTHFKKNIYKCVLMNEGKRLLFRLPEFTKMKNNLPLKLLLRLTNSYTLEMANVKVMGFILISLPLLMYFRDQLGLIELPWLYAVIFLALLSVFAQILSR
What is the function of this protein?
Involved in regulation of archaellar gene expression.  Activates flaB transcription upon nutrient starvation by acting on the flaB promoter.
What are the official names of this protein?
HTH-type transcriptional activator ArnR, Archaellum regulatory network protein ArnR.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTP10_ARATH
Sequence: MPLNSYIFFLFLTTSPRNTFFGIRTHSDRIMATEHITRTGDEYNVELLPSDDDAPPLESSWRLNLDAFQLPSSTGGRHDGRTRFSRYFRTPRKERRVSEYYKKQERLLEGFNEMETIHENGFASGVPTEEEMKKLAKSERLAVHISNATNLVLFVAKVYASMESRSMAVIASTLDSLLDLLSGFILWFTANAMRKPNQFHYPIGKRRMQPVGIIVFASVMATLGLQVLLESGRQLVAKSGIHMNSTEEKWMIGIMVSVTIVKFLLMLYCRGFQNEIVRAYAQDHLFDVVTNSIGLATAVLAVKFYWWIDPTGAILIALYTIATWARTVLENVHSLIGRSAPPDFLAKLTFLIWNHHEQIKHIDTVRAYTFGSHYFVEVDIVLPEDMRLQEAHNIGETLQEKLEQLAEVERAFVHIDFEFTHRPEHKCN
What is the function of this protein?
Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.
What are the official names of this protein?
Metal tolerance protein 10, AtMTP10.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: SC31A_CHICK
Sequence: MKLKEIDRTAMQAWSPAQQHPIYLATGTSAQQLDASFSTNASLEIFELDLSDPSLDMKSCATFSSAHRYHKLIWGPHSMTAGERVSGVLIAGGENGNVILYDPAKIIAGDTEVIIAQKDKHTGPVRALDVNMFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPLEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHNNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFTSSPLRVLESHTRGILAIAWSMADSELLLSCGKDAKILCSNPNTGEVLYELPTNMQWCFDIQWCPRNPAILSAASFDGRLRIYSIMGGSTDGLRQKHVDQLSSSFGNLDPFGTGQPLPPLQLPQQTAPQSVVLPLKKPPKWIRRPVGASFSFGGKLVTFENAKPQQQPGIDQQPQHHYVYVSQVVTEKEFLARSTQLQEAVQSEGFVSYCQKKVDMAQADFERNVWSFLKVNFEEDSRAKYLELLGYRKDDLKNKITSALNLNKECCADGELGEAPTESDVPLLNKGDEGQTAEEHFLGERAKDSKQETEDLGSERKTFNISVSGDVDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLSRTQEKYFSKIQSKITRLITAVVTKNWKEIVLSCDLQNWREALAAVLTYARPDEFAALCDLLGNRLESEGDSLLRTQACLCYICAGNVEKLVACWSKVQDGNSPLSLQDLIEKVVILRKAVQLTQAVDPNAVGALLAEKMSQYANLLAAQGSIAAALTFLPANTDQPDIVLLRDRLCRAQGELPAGQEAIKAPYERQPMPKDRAGPVAGQVPGPQASAQQYYQQGDKPPPPGFIMPGAINPSAPPQQATSPSYNMYSQAGTRPAYPQTYQTTQQYSFGTGETALYQPQQPVAAPASASYPSPASNTNPPYLPAAQPVPSPLYPGQPQPSPTSLNPASSFPPPPSGASFQHGRPGLPATSVAYALPTGPTGTLPAASDLPASQRTGPQNGWNDPPALNRAAKKKKVPDNFMPPVPITSPIMNPLADPQAQMQQPPAAPVGTPSFQPQQLSTGQQAPLGPYAPQALGPCVVPPTTFKPRTEGAPGAPIGNAIQALPTEKITKKPIPEEHLILKTTFEALIQRCLLSASDPQTKRKLDDANKRLEFLYDKLREQTLSPAIVSGLHNIVKSIETRNYVEGLNIHMHIVSTSNFSETSAFMPVLKVVLIQANKLGV
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein Sec31A, SEC31-like protein 1, SEC31-related protein A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Associates with membranes in a GTP-dependent manner. Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).
Protein: HEM1_BEUC1
Sequence: MLLSVSASHRDADLADLERLSSGVGRVWADAPLVAHGLDGAGVVLLATCNRFEVYLDVADGTDPQRALAVVRDLVRTVPESPLAAPGADDDAAGPGPDPSAALRVRVGDDAARHLFGVASGLDSIVVGEREIAGQVRRAIAAARRAGTTTGALERLFAQAQRTSRAVEAGTGLAAAGRSVVGVALDLAARSAPPWPLARVVLIGTGSYAGASLAALRARGCTDVRVHSESGRAEEFARAREAEAVPPGELLTAIADADVVVSCRGSVRPVLDAAAVAGARAAAERRAEERAGHAVGTAVQPRPLVVVDLALHRDVDPAVGSVDGVELLDLGTIRAHAPAAATRDVERAREIVDDAVAQHALVRAAREMDPAITRLRGRVREVLDAEVGRLPVGPVSREDAERALHRLAATLAHAPTEAAREAARAGRGEEYVEALRLLFPD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PLSB_PSEAE
Sequence: MPRYPFRRFGFGALRRLLYLWVRSETINQSAFTLKIDRSKPVLYVLQQPSVSDLAVVDTECRKAGLPRPVMPVAVGDAIEPAAFFYLTPEPDWLGRQDKRGASPTLVRMLAAVGQNGLDDAQIIPVSVFWGQSPDSESSPWKLLFADNWAVTGRLRKLARILILGRKTRVQFSAPIHLRELVEQGKGHERTLRMVNRILRVHFRNLKTAVIGPDLSHRRNLVKGLLRAPLVRQAISEECESERISQEKAEGIALRYANEIASDFSYPVIRFLEVILSWFWNKLYEGVKVNHIERVQDVAQGNEIVYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSILRRGGAFFMRRSFKGNQLYTAVFNEYLHTLFSRGFSTEYFVEGGRSRTGRMLHPRTGMLAITLRSFLRDSRRPIVFVPVYIGYERVLEGRTYLGELRGATKKKESIFDLFKVVGALKQRFGQVWVNFGEPIHLDQFLDRHQPDWQDQDLGPEYRPDWLPQTTNLLAKDVARHLNDAAAINPVNLVALALLSTSRQALDESALARILDLYLALLRKVPYSPSATLPDGDGQALIEYVKSMNLLAEQKDALGRILYLDEQNAVLATYYRNNVLHVFALPALIASFFQSNSRISREQLLRFARALYPYLQAELFIRWSLDELDAVIDQWLAALVEQDLLRQENDTFIRPAPSSRQYVLLILLARSVTQTLQRFYMAIALLLNAGQNALTAEELENLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLRVLRKDEAGKLSYHELLGELAEGAAKRVLPAEIRLSIRQVALERPAEEAAAESNDAAAN
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HEAT9_MACFA
Sequence: MAYEKSTDIFDISRSMFLYPWLEYPDRTKELRKAMAPVHLPLSCYQMPKEEFPPSPECWRQHPSKPNSVPYCYFNKPEIYTHWHDLYDQREEREAEKMLRKMRDDHRYIKEVHQTHIQMFHLPMSKLIIKSEMQSRPLEPTWDPLKWQRLRELTKSLESPREDEQLYAAQALGCLRISDKFVMKALQQVAQTGPEKVQYEAYRTLAILGCLNKHVIRALIKQLKEKNEGQRMETLTGLRMALNSWAAVSKDKRTQVGDEGKLVPVLQTLIKKSSSEASLEAALCLGFLRPRSNMVQEFLLQCLCQGLKTQQMKALRMLVKVMHVHSAPVIRAVLDQLCSSSVLEDRFEATQMLKTIGLEQIQAQGLEELTFNLLRRKTHNEPFLAVRQAVAQTVEELKLKPMMMNLVEAQLMNPDATARQEAVISLGVLGIRSPQVFHLLLDLLDAENRQAVKKSLQETLILCASIDPWIQNKLKNKVLSVYEAPKTNVKAEPTRFRKEPENPEELTIQDFRLAKLNPLFTAKSITKVGQKKTPAFPPYCSKPRKHRPQAIGPWQPRIKKQLRVLAEIAK
What are the official names of this protein?
Protein HEATR9, HEAT repeat-containing protein 9.
Protein: PSD_CHLL3
Sequence: MLTPYGRSTILKTTIFASAIAVTGLFFPPVSRAVLILSAAAILGFAFWFFRDPERTPAETGRVILAPADGRVILVEERDHPFTGSRSTLISIFMSPLNVHVNRIPQSGRIRHLQYHPGSFKMAFDHKSMEENERMDIGIESDSLKIFFSQVSGFIARRIVCPLRMDEAVEAGKRFGMIKFGSRVDIIIPQGSTPAVTIGGKTRAGETVIARW
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: G6PI_SALSV
Sequence: MKNINPTQTSAWQALQKHYDEMKDVTIAELFANDSDRFAKFSATFDDLMLVDFSKNRITEETLAKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALRNRSNTPIIVDGKDVMPEVNAVLEKMKTFSQAIISGQWKGYTGKAITDVVNIGIGGSDLGPFMVTEALRPYKNHLTMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKSAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIILSVGFDNFVELLSGAHAMDKHFSTTPAEKNLPILLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPAQLEHVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGAILNIFTFDQWGVELGKQLANRILPELGDDKAISSHDSSTNGLINRYKAWRA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO1C_THECE
Sequence: MVAAKTIKGMVDKAELPDNIKEELYAKLIEYNKKYKLKKAEVQAIIDETVKEYQKALIEPGEAIGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPIMTVYLDEEHRYDREKALEVARRIEGTSLENLARETTIDILNFEFIVEIDPERLEKAGLDMERIQRKLESSFKSAEFEVDGYTVIMRPKKVGKISSLRRLAEKVKKHRLKGLSRVGKTVITKDSKTGEYIIRTEGSNFKQVLKVPGVDPTRTRTNDIREIAEVLGIEAARNAIIDEILKTMEEQGLEVDVRHIMLVADMMTLDGVIRPIGRHGIVGEKASVLARAAFEITTQHLFEAAERGAVDPLNGVVENVLIGQPVPVGTGTVKLAMNLPLRPKRE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADR_ECODH
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.