PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_STAS1
Sequence: MTTVYYDQSVTKDALQGKKVAIIGYGSQGHAHAQNLKDNGYDVIIGIRPGCSFDKAKDDGFEVYPVDEAAKQADVIMVLLPDEIQGQVYKEEIEPNLEANNALVFAHGFNIHFGVIQPPENVDVFLVAPKGPGHLVRRTFAEGSAVPALFAVEQDPSGEARDLALSYAKGIGATRAGVLETSFKEETETDLFGEQAVLCGGTTKLVQSGFETLVEAGYQPEIAYFEVLHEMKLIVDLMYEGGMENMRYSISNTAEFGDYVSGPRIITPDVKDNMKAVLDDIQKGNFSDRFIKDNQNNFEEFHKLREEQHGHQIEAVGRELRDMMPFIKSKSIEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RGS19_MOUSE
Sequence: MPTPHEAEKQHTGPEEADRPPSMSSHDAAPSGPPSRNPCCLCWCCCCSCSWNQERQRAWQVSRESKLQPLPSCEVCTPPSPKEVQSWAQSFDKLMHSPTGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINRKMQEPSPHTFDDAQLQIYTLMHRDSYPRFLTSPTYRSLLLQGAPQSSEA
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2.  Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 19, RGS19.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: SCLY_BOVIN
Sequence: MEAAGARNRDARSRAEKSPPESRKVYMDYNATTPLEPEVIEAMTEAMREAWGNPSSSYPAGRKAKEIINTARENLAKMIGGQPQDVIFTSGGTESNNLVIQSVVKHFHKVHAANGDTGGHPNPVDGALPHIITCTVEHDSIRLPLEHLREERVAEVTFVPVSKVNGQVEAEDILAAVRPATCLVTIMLANNETGVIMPVPEISRRVRALNQQRVAGGLPGVLVHTDAAQALGKQRVDVRDLGVDFLTIVGHKFYGPRIGALYVRGLGEHTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVAENGEAYEAHMRGVRDYLEERLAAEFGERIHLNSQFPGAERLPNTCNFSIRGPQLQGRAVLAQCRTLLASVGAACHSDLGDRPSPVLLSCGVPVDVARNAIRLSVGRSSTRAEVDLVVQDLKQAVARLEGQA
What is the function of this protein?
Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.
What are the official names of this protein?
Selenocysteine lyase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RBY1A_MOUSE
Sequence: MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI
What is the function of this protein?
RNA-binding protein involved in pre-mRNA splicing.  Required for sperm development.  Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN.  Binds non-specifically to mRNAs.
What are the official names of this protein?
RNA-binding motif protein, Y chromosome, family 1 member A1, RNA-binding motif protein 1, Y chromosome RNA recognition motif 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DER_MESFL
Sequence: MKKGIVAIVGRPNVGKSSLFNRIIREKKSIVEDTPGVTRDRIYGTAEWLTREFIVIDTGGITLEDQPFAKEIKVQAEIAMEEADVIVFLLNHQEGLSDEDKMIAKILYKTKKPIVLAVNKYDKKTSDFDQYEYMSLGFGEPILISATHGIGTGDLLDDIIHQMPSHEEINKDNRTRVSIIGRPNVGKSSLVNSLIGEERMIVSDIPGTTLDAVDSVVKVNNIEYTLIDTAGIRKKSKIFQNVEKYSYLRSLTTINGSDVVLLMLDASVPISDLDTNIGGLAFEEKKPIIIIANKWDLVENKEKEILKKEDEIRAYFKYLAYAKILFVSAHDKTRITKIFTAVEDIRTALDKKIKTSVFNEVLNKAQLINPAPNFNGGRLKIYYGAQVEAYLPTFVLFVNNPDYVHFSYKRFLENQIRLQFGFEGVPMSIIFRERK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TSAD_MYCGA
Sequence: MYYKVILGIESSCDDLSIAIAIDNKIVTTKTKSSSSVHANYGGVVPEIAARYHEEILHQTLNEALTEANLTINKIDLITYTENPGLLNCLHVAKVFANTLGYLLKIPAQGINHLYGHIFSPMIDDGDCLYQKSDLIYPALGIVVSGGHTAIYDVQSPSKITLLDETLDDAIGEVYDKVGRALGLQYPAGAKIDQLYNPEQAETVEFLKTNKLSAFSYSGFKSAVLRYIELNKNQPDFNLVQAVSSFQKFIIDDFIDRIKNVINKADSKYQTILLGGGVSANSYLRSELKELAIKTLVPKPIYSGDNAAMIINYAQYLLNE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCE_ASFB7
Sequence: MASLDNLVARYQRCFNDQSLKNSTIELEIRFQQINFLLFKTVYEALVAQEIPSTISHSIRCIKKVHHENHCREKILPSENLYFKKQPLMFFKFSEPASLGCKVSLAIEQPIRKFILDSSVLVRLKNRTTFRVSELWKIELTIVKQLMGSEVSAKLAAFKTLLFDTPEQQTTKNMMTLINPDDEYLYEIEIEYTGKPESLTAADVIKIKNTVLTLISPNHLMLTAYHQAIEFIASHILSSEILLARIKSGKWGLKRLLPQVKSMTKADYMKFYPPVGYYVTDKADGIRGIAVIQDTQIYVVADQLYSLGTTGIEPLKPTILDGEFMPEKKEFYGFDVIMYEGNLLTQQGFETRIESLSKGIKVLQAFNIKAEMKPFISLTSADPNVLLKNFESIFKKKTRPYSIDGIILVEPGNSYLNTNTFKWKPTWDNTLDFLVRKCPESLNVPEYAPKKGFSLHLLFVGISGELFKKLALNWCPGYTKLFPVTQRNQNYFPVQFQPSDFPLAFLYYHPDTSSFSNIDGKVLEMRCLKREINYVRWEIVKIREDRQQDLKTGGYFGNDFKTAELTWLNYMDPFSFEELAKGPSGMYFAGAKTGIYRAQTALISFIKQEIIQKISHQSWVIDLGIGKGQDLGRYLDAGVRHLVGIDKDQTALAELVYRKFSHATTRQHKHATNIYVLHQDLAEPAKEISEKVHQIYGFPKEGASSIVSNLFIHYLMKNTQQVENLAVLCHKLLQPGGMVWFTTMLGEQVLELLHENRIELNEVWEARENEVVKFAIKRLFKEDILQETGQEIGVLLPFSNGDFYNEYLVNTAFLIKIFKHHGFSLVQKQSFKDWIPEFQNFSKSLYKILTEADKTWTSLFGFICLRKN
What is the function of this protein?
Probably catalyzes the second reaction in the mRNA cap formation pathway (Probable).  Forms a covalent complex with GTP (PubMed:8382399).
What are the official names of this protein?
mRNA-capping enzyme, VTF/CE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: RL9_BACMK
Sequence: MKVIFLKDVKGKGKKGEIKNVPDGYANNFLLKQGLAAEATNSSMKTLDAQKRKEEKDAAAEVENAKELKETLEKLTVEVKAKSGEGGRLFGSITSKQIVDVMQKSHKIKLDKRKFEMDDAIRALGYTNVNVKLHPQVTATVKVHVSEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RSMH_BURTA
Sequence: MGNELQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLSDAGRLIAFDKDPRAIETASGIEDARFEIVHDSFAAMKGALDARGVGRVSGVLLDLGVSSPQVDDPERGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLVVISFHSLEDRIVKRFLQTHASAPAVDRRLPIRAVDLPSPPLKLLGRMFPSDAEVAANPRARSAVMRIAERVAP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_ACHLI
Sequence: MLNTYITNILGIKLTEQQNGQFDAYYNLLVAYNKHTNLTRITSRDDADIKHFLDSVLISKLVDLNKVVTLCDMGAGAGFPSIPLLIVFPNIQVTIVESQIKRVQFLQELKQALGLEFNIVHDRAENFSSKNYQQFDIVTARALGELRLILEFGVPMLKVGGHFIAPKGSKFEEELTSAAHAIKVLNVELITQDLFELPLESGFRANLLFRKEKHVSGYPRPFPIIKKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOL_ORYSJ
Sequence: MAATAAYLPLRAQAQVGLAPLRPSGSAAAGARLPGRTARRRLAARGGPEAAGIRAEAVPGGGGVARRAAMVPPYNVLITGSTKGIGYALAKEFLKAGDNVVICSRSAERVESAVTDLKKEFGEQHVWGIVCDVREGKDVKALVDFARDKMKYIDIWINNAGSNAYSYKPLVETSDEALMEVITTNTLGLMICCREAINMMRNQPRGGHIFNIDGAGSDGRPTPRFAAYGATKRSVVHLTKSLQAELQMNEVNNVMVHNLSPGMVTTDLLMSGATTKQAKFFINILAEPANVVADYLVPNIRAIPTNQSMKPTYIRFLTGLKAYSRIFSRIAFGARRNKYVAED
What is the function of this protein?
Required for chlorophyll b degradation.
What are the official names of this protein?
Chlorophyll(ide) b reductase NOL, chloroplastic, Protein NON-YELLOW COLORING 1-LIKE, OsNOL, Protein NYC1-LIKE, Short-chain dehydrogenase/reductase NOL.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: SELU_PSEE4
Sequence: MRPDCTDFNTLFLDDVPMMDMRAPIEFTKGAFPGVVNLPLMNDQERQKVGTCFKQQGQSAAIALGHQLVNGALKQQRLEAWAAFAQAHPDGYLYCFRGGLRSQIVQGWLKEAGIQYPKVVGGYKAMRTFLLDTTQQAVEQCDFVLLGGLTGTGKTDVLQQLDNVLDLEGHANHRGSSFGKRATAQPAQIDFENGLAIDMLKKRARGIGQFVLEDEGRIVGSCTVPLGLYQGMQRYPLVWLEDAFDNRVERILRDYVTNLCAEFVAVHGEEDGRRLFAERMRQSMANIYKRLGGERFQRLSELLGQALDEQLRSGDVSLHRGWIEGLLKEYYDPMYAYQREAKAGRIEFAGDGVEVREYLKARARRQHRVDL
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: BMT3_KOMPC
Sequence: MRIRSNVLLLSTAGALALVWFAVVFSWDDKSIFGIPTPGHAVASAYDSSVTLGTFNDMEVDSYVTNIYDNAPVLGCYDLSYHGLLKVSPKHEILCDMKFIRARVLETEAYAALKDLEHKKLTEEEKIEKHWFTFYGSSVFLPDHDVHYLVRRVVFSGEGKANRPITSILVAQIYDKNWNELNGHFLNVLNPNTGKLQHHAFPQVLPIAVNWDRNSKYRGQEDPRVVLRRGRFGPDPLVMFNTLTQNNKLRRLFTISPFDQYKTVMYRTNAFKMQTTEKNWVPFFLKDDQESVHFVYSFNPLRVLNCSLDNGACDVLFELPHDFGMSSELRGATPMLNLPQAIPMADDKEIWVSFPRTRISDCGCSETMYRPMLMLFVREGTNFFAELLSSSIDFGLEVIPYTGDGLPCSSGQSVLIPNSIDNWEVTGSNGEDILSLTFSEADKSTSVVHIRGLYKYLSELDGYGGPEAEDEHNFQRILSDLHFDGKKTIENFKKVQSCALDAAKAYCKEYGVTRGEEDRLKNKEKERKIEEKRKKEEERKKKEEEKKKKEEEEKKKKEEEEEEEKRLKELKKKLKELQEELEKQKDEVKDTKAK
What is the function of this protein?
Beta-mannosyltransferase involved in cell wall biosynthesis.
What are the official names of this protein?
Beta-mannosyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the BMT family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RS8_THEVO
Sequence: MRNDTLNDVINSIKNASRLGRREIIAEPAAKLIGKVLKVMQDYNYIKSFEVIDESRGGKFKIVLNTTINNCGVIKPRFPVKNENLEKYESRYLPAEDFGILILTTTKGVMSNIEARKLGIGGKLLAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: UREF_CORGB
Sequence: MDLDADFLLLHLSDSALPTGAFAHSFGFETYMDAERITNAEEFQDWLKVLLKVQLTSSDALAMRMFYATPTASELKRLDERLFAGTPAREVREANARMGTRMAEIVAETYSVPLIIEYLELIKNRELSGHPALALALATHSMGIDVDRAIHAHLTATVSSLIQNAVRGIPLGQMAGQRVMFAMREHIGAAVKRSAMLDAIDFCSGDPGLDISQMVHETQRARLFMS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y829_SYNY3
Sequence: MATIFRTWSYQYPWVYALVSRLATLNVGGEERFHQLPLENLAISPGQKVLDLCCGGGQATVYLAQSGATVVGLDASPKALGRAKINVPQATYVQGLAEDLPFGEGEFDLVHTSVALHEMTPAQLQSIISGVHRVLKPGGIFALVDLHRPSNWLFWPPLAIFMGLFETETAWQLINTDLGSLLDQAGFTVVRKHLYAGGSLQVIQARANKTVN
What are the official names of this protein?
Uncharacterized methyltransferase sll0829.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: SSRP_PSET1
Sequence: MAKNKSSKSTSNTIALNKKARHEYFLHDKFEAGVELQGWEVKSIRAGKVNITETYIHLKNGEAFLLGAQIQPLNSASTHVICDPLRYRKLLLSRRELDRLVGATERDGYSLIATAMYWKNCWVKLEFHLAKGKKLHDKREDGKDKDWSREKERLMKHKA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SODM_MYCLE
Sequence: MAEYTLPDLDWDYAALEPHISGEINEIHHTKHHAAYVKGVNDALAKLDEARAKDDHSAIFLNEKNLAFHLGGHVNHSIWWKNLSPNGGDKPTGGLATDIDETFGSFDKFRAQFSAAANGLQGSGWAVLGYDTLGNKLLTFQLYDQQANVSLGIIPLLQVDMWEHAFYLQYKNVKADYVKAFWNVVNWADVQSRYMAATSKTQGLIFD
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: APAG_XANOM
Sequence: MHDDPRYRVEVEVSPRFLAHQSTPDEGRYAFAYSIRIQNAGAVPARLIARHWQITDGNGRTEQVDGEGVVGEQPRLRPGEAFHYTSGVLLETEQGQMQGHYDMVADDGTEFIAPIAAFVLSVPRTLH
What are the official names of this protein?
Protein ApaG.
Protein: CH60_LEPBJ
Sequence: MAKDIEYNETARRKLLEGVNKLANAVKVTLGPKGRNVVIDKKFGAPTITKDGVTVAKEIELEDALENMGAQMVKEVSTKTNDVAGDGTTTATILAQSIINEGLKNVTAGANPMSLKRGIDKAVTAAVESIRKRAVKIENKKDIANVASISANNDDTIGNLIADAMDKVGKDGVITVEEAKSIETTLDVVEGMQFDRGYISPYMVTDAESMVATLSDPYILIYDKKISSMKDLIHILEKVAQAGKPLVIISEEVEGEALATIVVNTLRKTISCVAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGMKLENTTLQMLGRANKVTVDKENTTIIEGKGQTKEIQGRIGQIKKQIEDTTSEYDKEKLQERLAKLAGGVAVIHVGAATEVEMKEKKARVEDALSATRAAVEEGIVPGGGLTLLKAQEAVAALKLEGDEATGAKIIFRSLEEPIRMITNNAGLEGSVIVEHAKTKKGNEGFNALSMVWEDLVSAGVVDPAKVVRSALQNAASIGSMILTTEVTITDKPEKDAPNPMAGMGGGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_PROMH
Sequence: MSDLPELHWLHGKPTATGRLKSTPEDFKVSEDLGFTLDGEGEHVMVRVRKTGCNTAFVAEKLAKFAGIHPRDASYAGLKDRNAVTEQWFCLRMPGKEMPDFSQFTLEGCEILTTTRQQRKLRIGTLKGNHFTLVLRDISDVTSVETRLVEIQKQGVPNYFGVQRFGRNGDNLRQAWRWATNEIRVKERSKRSFYLSAARSAMFNHLVSQRLERHIYTQVLCGDAMQLHGKRSWFVAEGAELAQIQTRYEEHDIHITAPLPGKGDLGTQAQALIFETDNLADYEALWSLAQQERVDTTRRAINLLPENMSWHWLDDTTVSLSFFLPAGSFATSVVRELILLGNIDAENISE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: BDNF_RAJCL
Sequence: KCNPKGFTNEGCRGIDKKHWNSQCRTSQSYVRALTMDSRKKIG
What is the function of this protein?
Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: FANCA_HUMAN
Sequence: MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLEAVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQMFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFGVFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYRRLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFESCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQQAAPDADLSQEPHLF
What is the function of this protein?
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function.  May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
What are the official names of this protein?
Fanconi anemia group A protein, Protein FACA.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Protein: AROK_PSEA6
Sequence: MAEKRNIFLIGPMGAGKSTIGRHLADELHLEFYDSDQEIEKRTGADIAWIFDLEGEEGFRAREETVINDLTDKQGIVLATGGGSVVSKAVRNRLSARGIVVYLQTTIDKQVARTQRDKRRPLLQKDDPETVLRRLAEERNPMYEDAADYIVDTDEQSARAVANQIIEKINQ
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PANTR
Sequence: MNENLFASFAAPTILGLPAAVLIILFPPLLVPTSKHLINNRLITTQQWLIQLTSKQMMTMHSTKGRTWSLMLVSLIIFITTTNLLGLLPHSFTPTTQLSMNLAMAIPLWAGAVVMGFRFKTKNALAHFLPQGTPTPLIPMLVIIETISLLIQPMALAVRLTANITAGHLLMHLIGSATLALSTINLPYALIIFTILILLTILEIAVALIQAYVFTLLVSLYLHDNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL1_PORGI
Sequence: MSKLTKKQKLAFSKIEPGKAYTISEASALVKEITTTNFDASVDIDVRLGVDPRKANQMVRGVVTLPHGTGKQIRVLALCSPDKEAEAKEAGADYVGLDEYIEKIKAGWTDIDVIITMPAIMGKIGALGRVLGPRGLMPNPKSGTVTNDVGAAVKEVKAGKIDFKVDKTGIVHTSIGKVSFSADQIRDNAREFINTIIKLKPTTAKGTYIKSIYLSSTMSFGIKVDPKTVDEN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.