PharMolix/UniProtQA huggingface dataset:
Protein: CRE5_PHYIT
Sequence: MQTIQLIIFVAFVLSRAAASISSFSDPTSIVNINHDANRLSRALAAGQNQTQRSLRQHEGEDRGAIDKADEVVSKMKALMGTAKNVPNNLAALIAKRSKTAGEFVRRPFLVSKLSKRYNIADQLSFSTLKQLDKIDNMRIVDIKNGIKGNKKTPNGMRRKIKHFEGMKTAPQKFLESHVGRDMQRYGKDGSRWLSAGVVTRTTDQGERQILLISSSNPARGDFLLPKGGWDRGEKIKKAALREVMEEGGVCRAL
What is the function of this protein?
Effector that is involved in host plant infection.  Contributes to virulence during the early infection stage, by inhibiting plant defense responses induced by both PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI).
What are the official names of this protein?
RxLR effector protein CRE5, Core RXLR effector 5.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus, host nucleolus. Host nucleus.
Protein: KTHY_THET2
Sequence: MPGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLLLTQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRRPDRLEGLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: INSI1_XENTR
Sequence: MQTLEEHCWSCSCTRGRDKKGTRLSTWLAQRAAKAMSSLNSLLSLAYHTLASSEGRSLIRRSLVLFAVGVFLALVLNLLQIQRNVTLFPEEVIATIFSSAWWVPPCCGTAAAVVGLLYPCIDSHLGEPHKFKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAMGSSEKTHSD
What is the function of this protein?
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of scap and degradation of hmgcr.  Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs).  Binds oxysterol, including 25-hydroxycholesterol, regulating interaction with scap and retention of the SCAP-SREBP complex in the endoplasmic reticulum.  In presence of oxysterol, interacts with scap, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing scap from escorting SREBPs to the Golgi.  Sterol deprivation reduces oxysterol-binding, disrupting the interaction between insig1 and scap, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBPs.  Also regulates cholesterol synthesis by regulating degradation of hmgcr.
What are the official names of this protein?
Insulin-induced gene 1 protein, INSIG-1.
What is the protein family that this protein belongs to?
Belongs to the INSIG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: STAT6_HUMAN
Sequence: MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDTVQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMPFHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription.  Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.
What are the official names of this protein?
Signal transducer and activator of transcription 6, IL-4 Stat.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Protein: RIR2_IIV6
Sequence: MSLLKGRNYYKPFTYPEFYNKWDKHEKSHWLPSEVPMHDDVNDWKNRLNDNQRDFLTNIFRFFTQGDVDVASAYYTQYLPFFKLPEVTMMMGGFAGREGVHIDAYSYLLETLGMPEATYKEFLMYEEMKDKQDYIKKFSDSRHILGKGEENLTTEDKEHIAAGIALFSGFTEGMQLFSTFAMLLIFPLNGFMKGMGQIVTWSIVDETQHTEGMIELFKVFVEENKTGDQPIRPSVLQETVYKIAKEMVGLEEAFIDLVFKKYKDEPINDDNDLETKDNKDFFGLTPQRLKAYIKYIADRRLNLMGYKSIFNLEPYPTNPLPELEIMINAPTHTNFFENRSTDYANVSTKGTWSEIWNKPQ
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Probable ribonucleoside-diphosphate reductase small subunit 376L, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: RL7_STRSV
Sequence: MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAAGAGEAAAAKDSFDIELTAAGDKKVGVIKVVREITGLGLKEAKELVDGAPNVIKEGVAAAEAEELKAKLEEAGASVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: GPMB_ECOSM
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: Y548_STAES
Sequence: MTSNEKEMGKSELLVVTGMSGAGKSLVIQSLEDMGFFCVDNLPPVLLPKFVELMAQGNPSLQKVAIAIDLRGKELFKSLVKEIDIIKSRNDVILDVMFLEAKTEKIISRYKESRRAHPLNEQGQRSLIDAINEEREHLSEIRSIANYVIDTTKLKPKELKQRISKFYLDENFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVEELRPFTGLDEPVYNYVMKWKETQIFFDKLTDLLKFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAKRLAEYLNEIFEYNVYVHHRDAHIESGER
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SE_0548.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: MUC3B_HUMAN
Sequence: MQLLGLLSILWMLKSSPGATGTLSTATSTSHVTFPRAEATRTALSNSPHSRYLAEWPQGVPQLASPAPGHRENAPMTLTTSPHDTLISETLLSSLVSSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTSFIITISHSTSICVTTTQVTFTSSYTPTPVTQKPVTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTLSSLTSSILSSTPAPNTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTPSFMSSIITTETTSHSTPSFSSSTIHSTVSSSTTAITSPFTTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLSLSTSTSLTTTTDLPSIPTDISSLPTPIHIISSSPSIQSTETSSLVGTTSPTMSTVRATLRSTENTPISSFSTSIVVTPETPTTQAPPVLMSATGTQTSPVPTTVTFGSMDSSTSTLHTLTPSTALSKIMSTSQFPIPSTHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFATTIHSVPSSPYIFSTENVGSASITAFPSLSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPSSISMQTTLATHMDTSSMTPESESSIIPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNNSVIPTPLPGVSTIPLTMKPSSSLPTILRTSSKSTHPSPPTARTSQTSVATTQTPTTLTTCRTTPITSWMTTQSTLTTTAGTCDNGGTWEQGQCACLPGFSGDRCQLQTRCQNGGQWDGLKCQCPSTFYGSSCEFAVEQVDLDVVETEVGMEVSVDQQFSPDLNDNTSQAYRDFNKTFWNQMQKIFADMQGFTFKGVEILSLRNGSIVVDYLVLLEMPFSPQLESEYEQVKTTLKEGLQNASQDANSCQDSQALCFKPDSIKVNNNSKTELTPEAICRRAAPTGYEEFYFPLVEATRLRCVTKCTSGLDNAIDCHQGQCVLETSGPACRCYSTDTHWFSGPRCEVTVHWRALVGGLTAGAALLVLLLLALGVRAVRSEWWGRQRRGRSWDQDRKWFETWDEEVVGTFSNWGFEDDGTDKDTNFHVALENVDTTMKVHIKRPEMTSSSV
What is the function of this protein?
Major glycoprotein component of a variety of mucus gels.  Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity).
What are the official names of this protein?
Mucin-3B, MUC-3B, Intestinal mucin-3B.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RSMH_MYCAP
Sequence: MENKHIPILLNEAIKSLNIKSDGIYLDLTVGMGGHSSEILKRLKNGLLVGFDKDLFAIEESRKRLSKIGSNFQLIHSDFNNVADELAKLNINAVDGILVDLGISSPQVDNAERGFSYSKDARLDMRMNTNQALDAHFVVNTYSEDELITIFYNYAEVKLAKQVANAIIKNRPINTTLELAEVIKSAYPAKLLSLKNPCKAVFQAIRIEVNNEFSSINSMLVQALNLLKKDSSLAIITFHSLEDSIIKKFFGNLIKSKHPSKMPIKEEKKYIVKVYSPSKAEISENNRSRSAKLRVLTKLI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_YERPB
Sequence: MMQDLRLILIVVGAIAIIALLLHGLWTSRKERSSLFRDRPVKRTKQERVETPIESLDEGVGEVRVRTSHPQEKPSFNHLDDDDDEVPVIQHAETKSAQVKTASRQAPFASVQTDYDDPLLGGLSAEQPPHDLSRDPLLGKADESYSQPQHAEPPHVEKPAHQVAPQQHVESQQEPVAPAPEAKPQKLKETVLVLHVAAHHGGVIGGEVLLQSVLQSGFQFGEMGIFHRHLSPAGSGPVLFSLANMVKPGSFDPDTMSDFSTPGVSMFMMVPSYGDANQNFKLMLQSAQRIADDVGGVVLDDERRMMTPQKLESYKARIREVLDANTIA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: ATPO_PICAN
Sequence: ASAAPIKPPVQLFGLDGTYATALFSASAKDSSIEKTFQSVQKLSSTISKDAKVAQVLSNPALSLNSRKEVVSVLSKELKLEPVVSNLLTVLAENNRLSLFDSIAKQFSVLNDAYNGVVEATVVSAKPLDSKILNRLTKSITNSKYVGPGKTLKIKNEVDPEILGGLIVEVADKSVDLSLASKVNKLNKVLSETI
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27791192).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).  Part of the complex F(0) domain and the peripheral stalk, which acts as a stator to hold the catalytic alpha/ATP1(3)beta/ATP2(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity).
What are the official names of this protein?
ATP synthase subunit 5, mitochondrial, ATP synthase chain 5, Oligomycin sensitivity conferral protein, OSCP.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Protein: ATPF2_PROMM
Sequence: MTSLLLFGAGGLFDFDATLPLMALQVVLLTFILNALFFRPVGRVVEEREVYVTTSRAEAKQKLAEAEKLELELKEQLKSARIAAQQLIQEAEKDSEQLYREALAIANADANAAREKARREIDAQRDSALSQLKGDAEKLGDLIVNRLLAAK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', ATP synthase F(0) sector subunit b', ATPase subunit II, F-type ATPase subunit b', F-ATPase subunit b'.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: GLGA_VIBCH
Sequence: MEQFNVWFTVSEVQGLVKSGGLADVAKALPQALKALHQQVAIALPAYRSVPGKEDAELVLETELTHWPHTQYRVLKRDLDGVPIYLIDCPAYFDRPALYAENNQAYADNGERFGFFSAACLDVLPKLGIQPDIIHANDWHTGLVPFLLKTRYRYDSFFEQVKSVLTVHNAIFKGIFSYHQLEVIPELNLSGMEFLQYGHDHVSMLRAGIAFADKVNAVSPNYAAELLTPLGAHGLVDDFVRRARDLHGIVNGCDYSEWNPRTDHYLPATYSDEPESMRKGKALCKTALQEELHLPVTDVPLFGMVCRLTHQKGFHYLLPILEQFLRNNVQVVIVGTGEPEVAARLNKIAHYHRAKFAFVETYSERLAHWVEAGSDFFLMPSEFEACGLNQIYSMAYGTLPIVREVGGLKDTVNDYDKFPERATGFGYQEPTPEALLITMQRALLFYLQQPEEMLKVQQRAMQQNFSWEESAQEYMKMYRLARFG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: NADK_STRA3
Sequence: MTQMNFTDRATRVAIIANGKYQSKRVASKLFAAFKHDPDFYLSKKDPDIVISIGGDGMLLSAFHMYEKQLDKVRFVGVHTGHLGFYTDYRDFEVDTLINNLKNDEGEQISYPILKVTITLEDGRVIRARALNESTIKRIEKTMVADVVINQVVFERFRGDGILVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVYRTLGSSVIIPKKDAIEIVPKRVGVYTISIDNKTVHYKNVTKIEYSIDEKSINFVSTPSHTSFWERVNDAFIGEPEH
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_ENTFA
Sequence: MAKKSKKMQEALKKVDATKAYSVEEAVALAKDTNIAKFDATVEVAYKLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGEKAKEAEAAGADFVGDDDMVAKIQGGWFDFDVVVATPDMMATVGKLGRVLGPKGLMPNPKTGTVTMDVTKAVEEVKAGKVTYRVDKAGNIHVPIGKVSFDNEKLVENFNTINDVLLKAKPSTAKGQYIKNISVTTTFGPGIHVDQASF
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SEC10_YEAST
Sequence: MNSLYELDPKWKKLLKTDNFLGGLTVNEFVQELSKDHRNDVLIDANTKNLPTNEKDQDAIREAIWKQLDPKPYIRTFESTLKELKNLNEETLNKRQYFSEQVATQEVIHSENVIKLSKDLHTTLLTFDKLDDRLTNVTQVVSPLGDKLETAIKKKQNYIQSVELIRRYNDFYSMGKSDIVEQLRLSKNWKLNLKSVKLMKNLLILSSKLETSSIPKTINTKLVIEKYSEMMENELLENFNSAYRENNFTKLNEIAIILNNFNGGVNVIQSFINQHDYFIDTKQIDLENEFENVFIKNVKFKEQLIDFENHSVIIETSMQNLINDVETVIKNESKIVKRVFEEKATHVIQLFIQRVFAQKIEPRFEVLLRNSLSISNLAYVRILHGLFTLFGKFTKSLIDYFQLLEIDDSNQILSTTLEQCFADLFSHYLYDRSKYFGIEKRSLEAILVDMTSKFTVNYDKEINKRVLLDKYKEKLSTNVDAFMHSPRGNTHSRQDSTSRSKLSQFNSFLKTHLDKDHLSLNRTNTLSDSFNNSSSSTQYDVANNSSSLVNSSFTASDIDNSPNSPANYSLNDVDSMLKCVVESTARVMELIPNKAHLYILEILKIMFLGIVDSYMEIALEVAYWKICKVDINKTAGVVNLNFLKFISMSTEILDLLSISIKSIFLPLLNNSPEIKAQIIEMTNSQIQKMEILINIILQETITVISTKFSAILCKQKKKDFVPKSQELLDQDTLPAIEIVNILNLIFEQSSKFLKGKNLQTFLTLIGEELYGLLLSHYSHFQVNSIGGVVVTKDIIGYQTAIEDWGVASLIDKFATLRELANLFTVQPELLESLTKEGHLADIGRDIIQSYISNREDFNHDNFINSVKLNFR
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component SEC10.
What is the protein family that this protein belongs to?
Belongs to the SEC10 family.
Protein: EIF3L_CULQU
Sequence: MYSNDDYAEGGYEEYGYEMAADDGYDRSFYPMHEDVKKFLVYFCSVIKGGVVYEIQNLYENTFPKLSEQHFEKKAWPSEDEVAHLVDNDNLFMILYKELYYRHLHARIQGGPSLEQRLNSFYNYCNFFNYILPSKEPVQLELPDIWLWELIDEFVYQFQNFAQYRARLTDKSDEEMDMLLNNNSKVWNILCILNVLHSLVSMSKIKDQLEAAAAGRDPEEVAGEFGRHSFYKMLGYFSLVGLLRVHSLLGDYHQAIKVLEPIELHKKSQYSHIPACQISTSYYVGFAYMMMRRYSDAIRTFSSILLYIQRTKQLYSARSYQNDQINKQTDQMYHLLAICLVLHPQCIDESIQQVLREKNYHDNMYKMQCGDLDTFRNFFVFACPKFVSPVPPPSDAPLDDYVKEALEHQTNVFMDEVRQQQELPTIRSYLKLYTTLPLLKLASFMDHIPQDEIGEQKIENLLTHLLCFKHKMKNIVWTKGASGLEGKFQSGSELDFYIDKDMIHIADTKVSHRYGDFFIRKILKFEDLNRRLHNLKG
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIGB_YERPS
Sequence: MNILNLKIIMFLLISNIIVVGGAWATSTCPDWPATRIAVEINALEQQLNKWSAAYHQQGHSPVTDDIYDQLQDKLRVWQSCRGLPDKTESQPIPGKGQFLHPVAHTGLKKLKDETALTRWMAGRKNLWVQPKVDGVAVTLVYHGGKLVQLLSRGNGVKGQNWTEKAPFISAIPQYIANAPALLTLQGELFLLMDGHQQAKSGGVNARSTVAGALMRKSPSPLLAQVGVFIWAWPDGPTTMKEKVALLQVMGFPFTAKYSEPVMSHLDVVQWRQFWFQAPLPFVTDGVVVRQEEEPAGRYWQATPGQWSMAWKYPPLQHIAEVKDIHFTLGRTGKGTVVLEVLPIKIDDKWIRRVNIGSVTRWKQWDIAPGDHITLALAGHGIPRLDNVVWRVHQRNTITAPNWDKFHQLSCFQRLPHGCEPQFLSRLIWLSGPGGLDIGGIGGGFWQKLIHHELINDLVGWLLLTPEQIASIPGIGNARAEKIYQQFQRAKQQPFSRWLLALGFPQVVSVDAQWQVVLRRSLSEWATMAGIGQMRAKQIKHFLDHPDVQALADFLSTQKVVGFELTE
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: EUTC_PHOLL
Sequence: MNQKTIEKNVSERVSNLKPHASPEITNEIESCMPDLGSLEAKQWIGVQNPNRIEVLQELRRSTVARVGTGRSGPRPRTQALLRFQADHSRSKDTVLKEVPTEWIEKQGLLEVQSQVSDKNLYLTRPDLGRKLSANAVETLLTQCKTAPDVQVVISDGLSTDAITTNYEDLVPPLLKGLEQAGMCIGTPFFVRYGRVKIEDQIGELLKAKVVVLLIGERPGLGQSESLSCYAVYQPTVEKTVEADRTCISNIHRGGTPPIEAAAIIVDLAKNMLEQQASGIALSR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: SYE_BIFLO
Sequence: MTDAENTKPELPKNVRVRFCPSPTGTPHVGMIRTALFNWAEARATGGTLIFRIEDTDAVRDSEESYNQILESLRWLGIDWDEGIDVGGPHGPYRQSERTAIYKDVAAKLLEAGYAYESFSTPEEIKERNLAAGRPAEFGYDGYDRNLTDEQKAAFRAEGRKPALRIKMPDEDIAFDDLIRGTIEFKAGSVPDYVIVRPNGDPLYTLTNPVDDAMMEVNVVLRGEDLLSSTPRQIVLYRYLMELGIAKEMPLFGHMPYVMGQGNKKLSKRDPESNLFNHRDNGFIREGLLNYLALLGWSIAPDRDVFSMDEMTEKFDVRDVKANPARFDIDKAISINAEHIRMLEPEDFLRRSVPYLHRDGVVSADNWDALTDREREVLTAAAPLVQPRVRLLGEVAGMVGSLLSTEGYLEPADDAKKQLKDSAGEVLDKAIAALEAVDEADWKTDNLHETLNKALVEEGGYKPRLAFGPVRVAMSGRRVSPPLFESMEIVGKPVSLARLKGLREHL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_CHLVU
Sequence: MSILSWIENQRKLKLLNAPKYNHPESDVSQGLWTRCDHCGVILYIKHLKENQRVCFGCGYHLQMSSTERIESLVDANTWRPFDEMVSPCDPLEFRDQKAYTERLKDAQERTGLQDAVQTGTGLLDGIPIALGVMDFHFMGGSMGSVVGEKITRLIEYATQEGLPVILVCASGGARMQEGILSLMQMAKISAALHIHQNCAKLLYISVLTSPTTGGVTASFAMLGDLLFAEPKALIGFAGRRVIEQTLQEQLPDDFQTAEYLLHHGLLDLIVPRSFLKQALSETLTLYKEAPLKEQGRIPYGERGPLTKTREEQLRRFLKSSKTPEYLHIVNDLKELLGFLGQTQTTLYPEKLEFLNNLKTQEQFLQKNDNFFEELLTSTTVKKALNLACGTQTRLNWLNYKLTEFRIRPKF
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CCNC_DICDI
Sequence: MAANFWESSHCTEWLLDRNKIEESNPKDKQYLTPIELKKLRTHYCFVIQNLGNALKLRQRAISTAIVYFKRFYLKNSFVDCEPRLVAVTCLYLSSKVEECITQAKKCAAKMKEIDHSFNYLMNDILECEFFVLEELDFCLIIYHPYKSLPFYLQSSGLDPASIEIIWGIVNDSYRTDVCLLYPPFVVGLGCILLGSYLLKKDIKQWLSELNVEMKDIWEVSKDLIDYYEFEKQQSLQNQSELDLLYNKLPIRNKK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity).
What are the official names of this protein?
Cyclin-C.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL31_ACTP2
Sequence: MKQGIHPEYTEITATCSCGNVIKTRSTVGKNLNLDVCGNCHPFYTGKQRVVDTGGRVERFNKRFSIPSTK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: EFTU_AQUPY
Sequence: MAKEKFERTKEHVNVGTIGHVDHGKSTLTSAITCVLAAGLVEGGKAKCFKYEEIDKAPEEKERGITINITHVEYETAKRHYAHVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHVLLARQVNVPYIVVFMNKCDMVDDEELLELVELEVRELLSKYEYPGDEVPVIRGSALGALQELEQNSPGKWVGSIKELLNAMDEYIPTPEREVDKPFLMPIEDVFSISGRGTVVTGRVERGVLRPGDEVEIVGLREEPLKTVATSIEMFRKVLDEALPGDNIGVLLRGVGKDDVERGQVLAQPGSVKAHRKFRAQVYVLSKEEGGRHTPFFVNYRPQFYFRTADVTGTVVKLPEGVEMVMPGDNVELEVELIAPVALEEGLRFAIREGGRTVGAGVVTKILD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.