PharMolix/UniProtQA huggingface dataset:
Protein: COAA_COXBN
Sequence: MTVKPELNEITPYLQFNRQEWGNFRKDTPLTLTESDLDKLQGQIEIVSLKEVTEIYLPLSRLLSFYVTARQTLQQATYQFLGKPEPKVPYIIGIAGSVAVGKSTTSRVLKALLSRWPDHPNVEVITTDGFLYSNAKLEKQGLMKRKGFPESYDMPSLLRVLNAIKSGQRNVRIPVYSHHYYDIVRGQYEIVDQPDIVILEGLNILQTGVRKTLQQLQVFVSDFFDFSLFVDAQAQVIQKWYIDRVLSFWRTTFKDPHSYFHYLTQMSETEAAAFAKHVWNEINKVNLMENILPYKNRAQLILEKAADHSIQKVYLRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCRB_METTE
Sequence: SDTVDIYDAGKILERVII
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase subunit beta, Coenzyme-B sulfoethylthiotransferase beta.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_FERNB
Sequence: MPKKRLVGVVVSDKMDKTVTVKVERLVKHAKFGKYVKRTKKFYAHDENNACRVGDVVEIEESRPLSKLKRWVVVNILERSKLSETPEIEETIDIEGGSEQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: EFTU_THEM4
Sequence: MAKEKFVRSKPHLNVGTIGHIDHGKTTLTAAITKYLSLFGRADYTPYEQIDKAPEEKERGITINIAHIEYETEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVNVPAMIVFINKTDMVDDEELVDLVEMEVRELLNKYEFPGDDLPVIRGSALKAVEASNDPNDEAYAPIKELLDTMDEYFPEPQRETDKPFLMPVEDVFSITGRGTVVTGRIERGVIRPGDEVEIVGMSYEVNKTVVTSVEMFRKILDEGLAGDNVGCLLRGIDKDEVERGQVLAKPGSITPHTTFKAQVYVLKKEEGGRHTPFQKGYKPQFFIRTADVTGELIEFPAGVEMVMPGDNVEMTIKLIYPVAIEEGMRFAIREGGRTVGAGVVTAIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVR1_PHYIT
Sequence: MGLMHRVLLLATFALLCMHAKAAGFDHDKVPRTVERGGGARQLRTATMSDDEARVSKLPSFIESFVKNRKIESWIQNKVTDDFVLSELKLVRLPGTSLADDPNFKLFQKFKIGGWLEEKATTTKAWENLGLDSLPFDQVSKIDEFKTYTQYVTVLNKKASKLDIDQWHGLLSGGSPEELMAKAMILRTLGRDVLERRVMLGGHVVVPF
What is the function of this protein?
Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying defense protein R1, through its interaction with this protein (PubMed:12000683, PubMed:25760731, PubMed:29910515).  Acts also as a virulence factor that promotes colonization and suppresses cell death induced by CRN2 as well as callose deposition, a hallmark of basal defense (PubMed:26336092, PubMed:30329083).  Interacts with host exocyst component Sec5 and thereby disturbs vesicle trafficking, a cellular process that is important for basal defense.  By targeting and stabilizing Sec5 in the cytoplasm, the exocyst complex is thus out of balance and not able to mediate the focal secretion of PR-1 and callose (PubMed:26336092).
What are the official names of this protein?
RxLR effector protein Avr1, Avirulence protein 1.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Host peroxisome. Note=Nuclear-localized Avr1 triggers the R1-mediated HR, whereas cytoplasmic localization is required for suppression of CRN2-induced cell death (PubMed:25760731). Also localized at Sec5-associated subcellular bodies (PubMed:30329083).
Protein: PURT_MYCS2
Sequence: MTTIGTPLSPRATKVMLLGSGELGREVLIALQRLGVETIAVDRYENAPGHQVAHHARTIAMSDPDQLRALIEAERPDLVVPEIEAIATPVLEALEAEGVTTVIPTARATRLTMDREGIRRLAAETLGVPTSPYRFCDSLAELQAAIDDEIGYPCVVKPVMSSSGKGQSKINGPDEVAAAWEYAMAGGRVSHTRIIVEGFVDFDYEITLLTVRARGADGEIATQFCEPIGHRQVGGDYVESWQPHPMPATALERAQEIAGAVTGNLGGQGIFGVELFVKGDQVWFSEVSPRPHDTGMVTMVTQWQNEFELHARAILGLPVDTTLRAPGASAVIYGGVDATGVVFDGVDAALQVPHTDIRLFGKPESFVKRRMGVALAFDDDVQTARRNAAEAASRMKPRAV
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: SMG9_XENLA
Sequence: MSDSGHSQPNVFIPGRNRRRRWMDQGPAGNLNLSEPGREKDSVLRDRDQERWEGNDEGCGYTIQKTPIILAKPASDRAKAATPAAPAPIEKPIVLMKAREEGKPTAPAEGAAVPPAAAVAKVEKEGQRPTQPVYQIQNRGMGAAASAGGSVDPVVGQAKLLPPQKMKHSIKLVDEYMNWCDSAIEFLLDQTDVLVVGVLGLQGTGKSTLMSLLSANSPDDDQRSYVFRMQSQEVRERAGNQTSGIDFFISQERIIFLDTQPILSPAILDHLINNDRKLPPEYNLPHTYVEMQSLQIAAFLFTVCHVVIVVQDWFTDFNLYRFLQTAEMLKPSTPSPSHESSGSSGSDEGIEYYPHIVFVQNKSKREDFCPRTLKQMHTVMDKLMLHSHLRYKGTLSMLDCNIFPGLPYDFVESEVNLFLIPTMESDADETISRAGTSGIPLFSLLPAYKGHPSFHSLVSRLRSQIMSMSRPQLSHTILTEKNWFHYAARIWDGVKKSSALSEYSRLLG
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Is recruited by release factors to stalled ribosomes together with smg1 and smg8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between smg1 and smg8 (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG9, Protein smg-9 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG9 family.
Protein: DEP3_ALTBR
Sequence: MVYSSTSSSQNRPDGEKHVEAVGSSTRIPSDELVDRGGGDTTTGKQSPRDIHGWKWATAYSAMLSTTLLFALDNTIVANIQPAIINDFGHLELLSWIGTGFALGTMFILLWGKVYGVFNIKWVYIFNIFLFEAGSALCGAAPNMAALIIGRVIAGVGGSGMYSGTLTYVSVLSNDQEKPAYLAGSTVVWGIGSVLGPVVGGAFAASSATWRWGFYVNLPIGAAFAPVYFLLFPSFDPYPSKTLAEKLRLVDWINAVIFLAGSACLTVVLTFGGVVYPFNSGTVIALWTVTGILLVAFIVLLKLHPLVAKENRLYPLHFFKQPTLINMQLQVFLSSGIILAMTYYVPLYFQFIKGDGALEAGVRLLPLIMFMVVASMVNGFLMPRYGLIPIWYIGGSSLALIGTALMYTVDDSTSNANIYGYNILIGAGTGSYIVAGFAIVQSLVPVHEIANAVGAMTIFQDLGMVLFLAISGSLFHNVAVDKVGKALPDVSHTEIANLIAGSSSKAFQALSDTEKALVIPEIASAMTTIWAFFLAAAALSVVCSFPLLKAKIGGMEKRTAITAA
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of depudecin, a highly oxidized eleven-carbon linear polyketide that acts as a histone deacetylase (HDAC) inhibitor and makes a small contribution to pathogenesis (PubMed:19737099).  Is presumed either to be responsible for exporting depudecin, to provide self-protection, or both (PubMed:19737099).
What are the official names of this protein?
Efflux pump DEP3, Depudecin biosynthesis cluster protein 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LOC1_ASPTN
Sequence: MAPTKGSAKGKADSKKSNPLASASKVSKKKAAKRPPPQEVKSKARTEASQLKKTKKREYSEAELDLPKLNSITPVGVVKPKGKKKGKVFVDDPEGMATILAIVNAEKEGQIESKMMKARQLEEIREAKLKEAEARQAQKKSKLEEAKDSIRNKKKHKGDGNAKSASTTAQTNDSSSKSKGKRKSVSFA
What is the function of this protein?
Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal subunit assembly/export protein loc1.
What is the protein family that this protein belongs to?
Belongs to the LOC1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DLTC_STREM
Sequence: MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVEIESIFNIKVPISEFGREDWNTANKIIQGIEELQHA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC1_SOLLC
Sequence: MVKAVAVLNSSEGVSGTYLFTQVGVAPTTVNGNISGLKPGLHGFHVHALGDTTNGCMSTGPHYNPAGKEHGAPEDEVRHAGDLGNITVGEDGTASFTITDKQIPLTGPQSIIGRAVVVHADPDDLGKGGHELSKSTGNAGGRIACGIIGLQG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn] 1.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_SHEAM
Sequence: MSQQHQAEIPKEIKEKGSLWLASLEAHHPESLTGLDTVQRRELEQVAGLSDFIARELSRHPERIARLFDGLLDKVDRSAFDRELHQALASVTSEDEAKAVLRRYRNFQMARLAWRDFTGKAPLGESLLDISSLAEALIITGRDWLYREMCQSLGTPMDADGRPQPLMILGMGKLGGRELNFSSDIDLIFTFPEHGETQGGRKSLDNQQFFIRMGQRLVNLLSQVTVDGFVFRVDMRLRPYGESGPLVVSFSALEDYYQEQGRDWERYAMVKARALGPWSGYSDELHSLLRPFVYRRYIDFSAIESLRRMKQLIAQEVRRRHLTDNIKLGAGGIREVEFVVQSFQLIRGGREPSLRTQSLFGAIDTLYSLGQLEYLAVDELKNAYVLLRRAENLLQAIDDKQTQTLPDNSLDWQRLCCALEMANEFDLRAHIEAAMAKIHRHFRATVGGEEAEDNHEHWTWQFWNVQEEDHAEALLQDQHIDDPALWPLLKGWRETMSRRPIGPRGRETLDRLMPKLLGELVSMPIPSAAFAPVFNVVEQVLTRTTYLELLCENPGARAQLVSLCCASPWIADQLAKFPMLLDELIDPAALYDITSLDDYGSELRQYLLRVPEDDMEQQMEALRQFKLTQQLKIAAADVTGVLPIMQVSDHLTFLAEAIIEQVVHQAWGQVASRHGVPAHLESGQMGFAVIAYGKLGGIELGYGSDLDLVFLHNYQGSGLTTGERQIETSHFYLKLAQRILHLFSTRTTSGELYEVDMRLRPSGASGLLVSEIERFGEYQQQEAWTWEHQALVRSRFVFGDNQLAARFSEIRAEVLGKVRDPAVLKGEVKAMRTKMREHLLKVDEGMFDLKQSPGGIADIEFIAQYLVLAGSAEFEDLTVWSDNVRIFQTAAELDILPLPVAQQLIAAYCTLRDENHRLTLQREAGQLPAIAVAEHSERVCAIYADVLGHDTDEPPLESRSQ
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: DAPE_RHOCS
Sequence: MAPDPIALARDLIRCPSVTPADAGALDRVQSVLEGLGFTCHRLPFQEPGTERVDNLYARLGDKGPNFCFAGHTDVVPAGDAAAWTVDPFGGEIIDGRLYGRGAADMKGGVAAFIAAVGSFLERNGPPAGSISLLITGDEEGPAVNGTRKVLDWMAAAGERIDACLVGEPTNPRALGDMIKVGRRGSLTATLTALGAQGHTAYPHLADNPLPRLAEALHLLASSPLDMGTPHFQPSTLALTSIDVGNPASNVIPARGTARFNIRFNDLHTPESLEAHIRDVLEEVGGAWELALQTSGVAFLTPPGALSDIVAAAVEAHTGRTPELSTSGGTSDARFIKDHCPVVEFGLVGASMHKVDENVAVADLLELTAIYRTVLERWFAGAEPRT
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PUR5_SHESW
Sequence: MSTPTPLSYKDAGVDIDAGNALVSNIKAAVKRTRRPEVMGNLGGFGALCEIPTKYKQPVLVSGTDGVGTKLRLAIDYKKHDTVGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVETATSVVNGIGEGCFQSGCALIGGETAEMPGMYEGEDYDLAGFCVGVVEKADIIDGSKVAAGDALIALASSGPHSNGYSLVRKVLEVSQADPQQDLNGKPLIEHLLEPTKIYVKSLLKLIEASDIHAMAHITGGGFWENIPRVLPDNCKAVIQGDSWQWPAVFSWLMENGNIAQYEMYRTFNCGVGMIVALPADKVDAALALLAAEGEQAWLIGAIAHREGNEEQVEIL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_BACAC
Sequence: MRVDGREKTELRHIHIHTNYLKHPEGSVLIEVGDTKVICSATIEERVPPFMRGEGKGWVTAEYAMIPRATEQRTIRESSKGKVTGRTMEIQRLIGRALRAVVDLEALGERTVWIDCDVIQADGGTRTASITGAYVAMVLAFEKLLQAEKVSKIPVKDYLAATSVGIVEEQGVVLDLNYAEDSKADVDMNVIMTGKGQFVEVQGTGEEATFSRAQLNELLDAAEQGIFQLIDIQKEALGDIVSHIE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: NIT1_YEREN
Sequence: MKNANVALLQLCSGENTRDNLAQIEQQIKQLNSGIQLVMTPENALLFANAASYRHHAEQHNDGPLQQEVREMARRYGVWIQVGSMPMISRESPDLITTSSLLFDSQGELKARYDKIHMFDVDIKDIHGRYRESDTYQPGEHLTVADTPVGRLGMTVCYDLRFPGLFQALRAQGAEIISVPAAFTKVTGEAHWEILLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGQNPDAVSALKVKIETTGLKTIRNQMPVLQHNRFVSSLVPRLSDSKQSSK
What is the function of this protein?
Hydrolyzes deaminated glutathione (dGSH, 2-oxoglutaramate) to alpha-ketoglutarate (alpha-KG) and cysteinylglycine (specific activity 6. 50 umol/min/mg), has less activity against alpha-ketoglutaramate (a-KGM, specific activity 0. 20 umol/min/mg), very little activity on glutathione and none on L-glutamine.  May function as a metabolite repair enzyme.
What are the official names of this protein?
Deaminated glutathione amidase, dGSH amidase, Nitrilase homolog 1, yeNit1.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: COPT5_ARATH
Sequence: MMHMTFYWGIKATILFDFWKTDSWLSYILTLIACFVFSAFYQYLENRRIQFKSLSSSRRAPPPPRSSSGVSAPLIPKSGTRSAAKAASVLLFGVNAAIGYLLMLAAMSFNGGVFIAIVVGLTAGYAVFRSDDGGADTATDDPCPCA
What is the function of this protein?
Involved in the transport of copper.
What are the official names of this protein?
Copper transporter 5, AtCOPT5.
What is the protein family that this protein belongs to?
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TGT_STRA1
Sequence: MTDHPIKYRLIKQEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKEMGSGIILSNTYHLWLRPGDELIAKAGGLHKFMNWDQAILTDSGGFQVYSLADSRNITEEGVTFKNHLNGAKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLNAHRRPHDQGLFGIVQGAGFEDLRRQSARDLVSMDFPGYSIGGLAVGETHDEMNAVLDFTVPMLPNDKPRYLMGVGAPDSLIDAVIRGVDMFDCVLPTRIARNGTCMTSQGRLVVKNAKFAEDFTPLDPNCDCYTCKNYTRAYIRHLLKADETFGIRLTSYHNLYFLVNLMKDVRQAIMDDNLLEFRQDFMERYGYGMNNRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: CHKB_RAT
Sequence: MAADGTGVVGGGAVGGPLSKDGLLDAKCPEPIPNRRRSSSLSRDAQRRAYQWCREYLGGAWRRARPEELSVCPVSGGLSNLLFRCSLPNHVPSMGGEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYLPSRPLKTQELRDPVLSGAIATKMARFHGMEMPFTKEPRWLFGTMERYLKQIQDLPSTSLPQMNLVEMYSLKDEMNHLRTLLDATPSPVVFCHNDIQEGNILLLSEPDSDDNLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTYEEWPFYKARPADYPTREQQLLFIRHYLAEVQKGEVLSEEEQKKQEEDLLIEISRYALASHFFWGLWSTLQASMSTIEFGYLEYAQSRFQFYFQQKGQLTSFLSP
What is the function of this protein?
Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis.
What are the official names of this protein?
Choline/ethanolamine kinase, Choline kinase beta, CK, CKB, Ethanolamine kinase, EK, choline/ethanolamine kinase beta, CKEKB.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.
Protein: OPA1_ONCMA
Sequence: MLRVGRAVACVACNNLASKNMGVRFRMPLQKLHPLSRAIHHRYNASANAQRPPHCSAARHFTSMSRLPMRPPKPSPGGHGGWRYQQHRSFWMLRLASRLLKLRYIVLGSAVGGGYTAKKTYEEWKDMLPDMSAYNWVIPDFVWELSDQIDLDKLTKILPELEEIAKLLPELPDFDKIGENFTFLKSILFTAEAPGDTPVKAATEAPVTATPEASDKQFKKSSDKEKVDQLQEELLRTQMKYQRMLERLEKENKDLRKVVLQKDEKGIHQRKIKKSLIDMYSEVLDILSDFDSNYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVAMFKDSSREFDLGKEEDLAALRHEIELRMRKSVKEGQTVSPETISLSVKGPGIQRMVLVDLPGVISTVTAGMAADTKETIFSISKNYMQNPNAIILCIQDGSVDAEADRHRPGQSNGPAGERTIFVLTKVDLAEKNLASPNRIQQIVEGKLFPMKALGYFAVVTGKGSAGESIDSIKDYEEDFFQNSRLLRDGMLKAHQVTTKNLSLAVSDCFWKMVRESVEQQADAFKASRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEAILQKKLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPHKALEVAWETLQEEFARFMAEYKGKDQDDIFDKLKEAVKDESIKRHKWNERAMDSLRVIQHNALEDRSITDKPQWDAAIQFMEETLQARLKDTDSVINDMVGPDWKQRWMSWKNRSPEQHTRNETRNELERLLKLHEDHTAYLANDEVTTVRKNLEGRGVEVDPALIKDTWHQLYRRHFLQKALQHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLLITANTLRQQLTNTEVRRLEKNVKEVLEDFGEDNERKVHLITGRRVQLAEDLKKVREIQEKLEAFIEALHKEK
What is the function of this protein?
Inactive form produced by cleavage at S1 position by oma1 following stress conditions that induce loss of mitochondrial membrane potential, leading to negative regulation of mitochondrial fusion.
What are the official names of this protein?
Dynamin-like 120 kDa protein, mitochondrial, 120 kDa G protein expressed in motor neurons, Optic atrophy protein 1 homolog, mG120.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space. Mitochondrion membrane. Note=Detected at contact sites between endoplasmic reticulum and mitochondrion membranes.
Protein: LEPA_SYNC1
Sequence: MERSKIRNFSIIAHIDHGKSTLADRLLETTGALSDREKTNQFLDKLDLERERGITIKAQAVRLKYRAEDGQDYILNLIDTPGHVDFSYEVSRSLAACEGGMLVVDASQGVEAQTLANVYLAIDQNLEVFPVLNKVDLPGAEPARIKEEIEEIIGLDASDAVEASAKEGIGIHEILESIVEKVPAPKGDADAPLKALIFDSWYDSYQGVIMLVRIFDGTLKKGDKIQLMASKRSYEVLKIGAFSPHPVEFSEMAAGEVGFVIAGIKVLQDAKVGDTVTHLHRPAENPLAGFQEVKPMVYSGLYPIDSGDYDALRDAMEKLRLNDSSFSFEPENSLALGFGFRCGFLGLLHMEIIQERLEREFNMELITTAPTVRYRVITTKGEELIVDSANKLPELQYIDQILEPFIVASIHVPNDYVGGVLALCEEKRGIQREIKYLTSNRVMVVYELPLNEIVLDFYDRLKTVSRGYASLDYEFLDYRPSDLVRLNILVNAETVDALSLIVHRDKSQMRGRELVAKMKEFIPRQQYEVAVQAAIGNKVVARANVKALRKDVTAKCYGGDITRKRKLLEKQKEGKKRMKQVGNVELPQEAFLAILKVKE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ALKH_DICD3
Sequence: MKNWKTSAEQILTAGPVVPVIVINKLEHAVPMAKALVAGGVRVLELTLRTECAVEAIRLIAQEVPDAIVGAGTVTNPQQLAEVTAAGAQFAISPGLTEPLLKAATEGTIPLIPGISTVSELMLGMDYGLREFKFFPAEANGGVKALQAIAGPFGKIRFCPTGGISLKNYRDYLALKSVLCVGGSWLVPADALESGDYDRITALAREAVAGATA
What are the official names of this protein?
KHG/KDPG aldolase.
What is the protein family that this protein belongs to?
Belongs to the KHG/KDPG aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_ACIB5
Sequence: MNLHEYQAKALLKEYGMPVQEGILATNADEAVAAFEQLGGKFAVMKAQVHAGGRGKAGGVKVAKSKEDVIEFANNIIGTRLVTYQTDANGQPVNSIIVAEDVYPVERELYLGAVVDRSSRRITFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQAREVAFALGLKDKQIGQFVKIMTAAYQAFVENDFALFEINPLSVRENGEILCVDAKVGIDSNALYRLPKVAALRDKSQENERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKIILADTSVQGVLINIFGGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKLLDESGLKLISANGLSDAAEKVVAAVKA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SYFA_PARMW
Sequence: MSAPVTLQQLTDQLDALEQQATTEISEASDAAALEQLRVGLLGKKGRISGVLWAMGKLPGSERPLVGQRANVLKTQVQSLLAERLAAVKQAAMAERIARESIDVTAPASGIPMGHRHPLITTTEEIVDLFLGLGYSVAEGPEVEKDYYNFTALNIPEDHPARDMQDTFYLQGDLLLRTHTSPVQIRHLEQNPPPVRIVAPGRVYRRDAVDATHSPVFHQVEVLAIDEGLDFSHLRGTVMAFLKAFFGDLPVRFRASYFPFTEPSAEVDVQWRGRWLEVMGCGMVDPAVLEGLGLDPERYSGFAAGLGVERFCMVRHGIDDIRRLYTSDLRFLEQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.