PharMolix/UniProtQA huggingface dataset:
Protein: SYP_LEGPC
Sequence: MRASQWFLVTQKETPNDAEIASHQLMLRSGMIRKLGSGLYTWMPLGLRVLRKVENIVREEMNKTHAMELLMPSVQPAELWQETGRWETFGGQLLTMKDSNQREYCFGPTHEEVITDIMRNELQSYKQLPVNFYQIQTKFRDEIRPRFGVMRAREFIMKDAYSFHLSIESLQETYKDMYQAYCRIFDRMGLKYRAVEADTGAIGGSASHEFQVLAESGEDLIFYSDASDYAANIEQATSLKPPKANQACNETITLVDTPNQKTIDEVASFLGIASNQTIKTLIVKGKEHPMVALVLRGDDELNEVKATKHPLVHSPLSFIDEELILKTLKTPLGSIGPIQLNIPVIVDHHALAMPSFVCGANQADKHFINAAWERDAKYDDAYDLRNVKEGDPSPDGRGMLHCCRGIEVGHVFQLGDKYAKAMNASVINEQGQLQTMIMGCYGLGITRVVAAAIEQHHDEHGIIWPQALAPFQVNIIPLNGARSQTVKEQAESLYQQLKSHGIDVLLDDRNERAGVLFADNDLIGIPHRLVVSERNLEQGCIEYKSRTSSETQLINLDKVVNFIIELINK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_SULSY
Sequence: MILAVDIGNTTTEIGYIKDLDKIETLKFKTDHGKTIDDWLINFSFFLNFYNLDETNINKIYISSVVPQVEEKITKALEKLLNVNPLLIGTDVKVPLKINYENPSEVGADRILNAFASINILNPPLIAIDFGTAVTFDVVNKNSEYDGGLIFPGLESSVNCLFSKTAKLPKVKIEKPSNIVGKNTISSIQSGIYNGYISLVEGVISKIEDEYKCKFNIILTGGHGKIISESLNLQHVFEQYLPIKGIYFLDKY
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_AGRFC
Sequence: MADLSSLKDLAPASEASAPVHVRKVDTLGRSYATGKRKNAVARVWVKAGSGKIIINGRDFTTYFARPVLQMILQQPLVAAARAGQFDIIATVAGGGLSGQAGAVRHGVSKALTYFEPGLRPVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: FTM_HUMAN
Sequence: MSGPTDETAGDLPVKDTGLNLFGMGGLQETSTTRTMKSRQAVSRVSREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRLGRDVEMEEMIEQLQEKVHELEKQNETLKNRLISAKQQLQTQGYRQTPYNNVQSRINTGRRKANENAGLQECPRKGIKFQDADVAETPHPMFTKYGNSLLEEARGEIRNLENVIQSQRGQIEELEHLAEILKTQLRRKENEIELSLLQLREQQATDQRSNIRDNVEMIKLHKQLVEKSNALSAMEGKFIQLQEKQRTLRISHDALMANGDELNMQLKEQRLKCCSLEKQLHSMKFSERRIEELQDRINDLEKERELLKENYDKLYDSAFSAAHEEQWKLKEQQLKVQIAQLETALKSDLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQENDINADELSEALLLIKAQKEQKNGDLSFLVKVDSEINKDLERSMRELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTRKMENLQQDYELKVEQYVHLLDIRAARIHKLEAQLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHLERGENLFEIHINKVTFSSEVLQASGDKEPVTFCTYAFYDFELQTTPVVRGLHPEYNFTSQYLVHVNDLFLQYIQKNTITLEVHQAYSTEYETIAACQLKFHEILEKSGRIFCTASLIGTKGDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKGPEHMQSLSQQAPKTAQLSSTDSTDGNLNELHITIRCCNHLQSRASHLQPHPYVVYKFFDFADHDTAIIPSSNDPQFDDHMYFPVPMNMDLDRYLKSESLSFYVFDDSDTQENIYIGKVNVPLISLAHDRCISGIFELTDHQKHPAGTIHVILKWKFAYLPPSGSITTEDLGNFIRSEEPEVVQRLPPASSVSTLVLAPRPKPRQRLTPVDKKVSFVDIMPHQSDETSPPPEDRKEISPEVEHIPEIEINMLTVPHVPKVSQEGSVDEVKENTEKMQQGKDDVSLLSEGQLAEQSLASSEDETEITEDLEPEVEEDMSASDSDDCIIPGPISKNIKQSLALSPGLGCSSAISAHCNFRLPGSSDFPASASQVDGITGACHHTQPSEKIRIEIIALSLNDSQVTMDDTIQRLFVECRFYSLPAEETPVSLPKPKSGQWVYYNYSNVIYVDKENNKAKRDILKAILQKQEMPNRSLRFTVVSDPPEDEQDLECEDIGVAHVDLADMFQEGRDLIEQNIDVFDARADGEGIGKLRVTVEALHALQSVYKQYRDDLEA
What is the function of this protein?
Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R) (PubMed:19464661).  May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity).  Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module.  Does not seem to be strictly required for ciliogenesis (PubMed:19464661).  Involved in establishment of planar cell polarity such as in cochlear sensory epithelium and is proposed to implicate stabilization of disheveled proteins (By similarity).  Involved in regulation of proteasomal activity at the primary cilium probably implicating association with PSDM2 (By similarity).
What are the official names of this protein?
Protein fantom, Nephrocystin-8, RPGR-interacting protein 1-like protein, RPGRIP1-like protein.
What is the protein family that this protein belongs to?
Belongs to the RPGRIP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, tight junction. Note=In cultured renal cells, it localizes diffusely in the cytoplasm but, as cells approach confluence, it accumulates to basolateral tight junctions. Localizes to the ciliary transition zone.
Protein: VKTH1_DENPO
Sequence: QPLRKLCILHRNPGRCYQKIPAFYYNQKKKQCEGFTWSGCGGNSNRFKTIEECRRTCIRK
What is the function of this protein?
Serine protease inhibitor homolog that blocks voltage-gated potassium channels (Kv1. 1/KCNA1, Kv1. 2/KCNA2, and Kv1. 6/KCNA6) (IC(50)=0. 13-50 nM).
What are the official names of this protein?
Kunitz-type serine protease inhibitor homolog dendrotoxin I, DTX-I, Dendrotoxin-1, Venom basic protease inhibitor 1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADK_SHEWM
Sequence: MPKAFQTIGLIGKPNHHGTNLTLKRLHHWLTMQGFEILVEERVAAEMGPKCNSVDLLELGDRCDLAIVVGGDGNMLGAARVLARFDIGVIGVNRGNLGFLTDLPPDSFEAALGDVLEGKFETEFRFLLETEVHRHGNMKSSNTAVNEAVLHPGKVAHMIEFEVYIDNNFMYSQRADGMIVSTPTGSTAYSLSAGGAILTPNLEALILVPMFPHTLSSRPIVVDACSIIKLVVSPENGDNLEVSCDGHVMLPVLPGDEIIIKRSHERLRLIHPKGHNYFHVLRNKLGWGSKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_GEODF
Sequence: MSITATQVNELRKATGAGLMDCKKALTETGGDHEQAVDYLRKKGLAAASKKAGRAATEGLVGSYIHAGGKIGVLVEVNCETDFVAKNEGFQNFVKDVAMHIAAASPLYVRREEVDPSVLEREKEIYRAKAKESGKPDNIVEKIIEGQVNKFYGDICLLEQAFVKDPDKTVQTYLNETIATIGENISIRRFAKFNLGEGLEKKESDFAAEVAAAAGA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAI3_DANRE
Sequence: MKDTSSKRPKSKEANKKKTKDKSNADNLPKPEEAAASEPGHPEYIFPLVLTSVSQELFGCRADEDVTAENPHKLLKKQDIIQDLRHRAAVCDFSPVKQAVLDYPEDELLLVFDRDFIYGQSFYLVLTVQAKESILKPPAEGADEQMEDEEQQEEEEEMMTKTPEPQPWVSLGSERLVYTPSAVLSSVICVRQLRYSVCPLGRRSGTRVRFSDRNALDWKEELVECSSYEDKSFSITRMERDSSTQTCRDNTHTCTQTLWKKPKNMWSQYEPREFSSEEKQHQLQSENLKNFITSVARRFEIYLQQNLIADVFCDDWTALCEDDASLMGKTETQLKEYQSFMDLHFSKEKTISHVQWHPSISGVIVVSMMERLSLEERIDSSTKLLLNPSHILFWSFSDPINPQLQLECPDDVLCFQFSPSDHNIIAGGCMNGQVVLWDISAHVDRLQDTRSGGKNILNKLGKSDATPVVRYCAVSGIENGHKAPITDIQWLPETFEVNKLGTPVENQSRTSVQLVTCAPDCCVLFWDLRAPRVMVHSLTDIKQKQEEKPLENPHGVPNTFTHLNLTWKPFIRVSLPKISSSGEYSPLRFSMRENTVDYNTGDKSVSGADSRVFAQLRMQSAKQQKPLQNISTKLYIATEDGELVYTDWKVEKDNDSGRMLSAKPLDVFLLQDTLLHTVSRSPFFRDIILTVGRFSFSIWREGLTCGPLLMSVYSKSMFSAGHWSRSRPAVLFMGREDGDVEVWDLLQNSRQPSHTQNISTAAISCIRTQTSSGNTHPYTETLHTHTHTQPPSAAYAHRPAPVTHTHTHKHCTHTHTHTHTHTHTHSRHQLHTHTDQLRVLEERVREAKQNLLAVSDRLGTLHILQIPGSLRRSSSSERQNVEKYFEKEEERLQYFEKRQSDHQKKKKETEAEQQKKKTELVTPPKQEEEVNAETLKEYQQFLTLEKLILKDMNIQNETQQTCNTINTP
What is the function of this protein?
May be involved in the regulation of cilia function.
What are the official names of this protein?
Dynein axonemal intermediate chain 3, WD repeat domain 63.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_MANSM
Sequence: MKLLMLCREPNLYSCRRLKMTAENAGHKMDILDPNRFLLKIQENRPHFALYYQPNQGTPYLLPDYDAVIPRFGTQSTKMGCSVLTHLAAKNIPCLNNPASFALARDKWLSLQALAAANIAVPVTVFAGQDFQAGSAVEKVSSPTILKTLNGSQGIGVILADRSQSAVSIMETLTLSHIPVLLQDFIGEAGASDIRCFVIGDKVVAAMQRSGQKGEFRANCHRGGITQQITLSDDEKLIAVRAAQALGLDVAGVDLIQSKKGLLVLEVNASPGLEMIEKTSGIDVATQMIAYLEKKIAGL
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: CCD63_HUMAN
Sequence: MSVLKKNRRKDSDTPQEPSEKAKEQQAEAELRKLRQQFRKMVESRKSFKFRNQQKIASQYKEIKTLKTEQDEITLLLSLMKSSRNMNRSEKNYMELRLLLQTKEDYEALIKSLKVLLAELDEKILQMEKKIANQKQIFAKMQEANNPRKLQKQIHILETRLNLVTVHFDKMLTTNAKLRKEIEDLRFEKAAYDNVYQQLQHCLLMEKKTMNLAIEQSSQAYEQRVEAMARMAAMKDRQKKDTSQYNLEIRELERLYAHESKLKSFLLVKLNDRNEFEEQAKREEALKAKKHVKKNRGESFESYEVAHLRLLKLAESGNLNQLIEDFLAKEEKNFARFTYVTELNNDMEMMHKRTQRIQDEIILLRSQQKLSHDDNHSVLRQLEDKLRKTTEEADMYESKYGEVSKTLDLLKNSVEKLFKKINCDATKILVQLGETGKVTDINLPQYFAIIEKKTNDLLLLETYRRILEVEGAEAEIPPPFINPFWGGSALLKPPEPIKVIPPVLGADPFSDRLDDVEQPLDHSSLRQLVLDNYILKENRSKEVRGDSLPEKVDDFRSRKKVTM
What is the function of this protein?
Plays a role in spermiogenesis.  Involved in the elongation of flagella and the formation of sperm heads.
What are the official names of this protein?
Coiled-coil domain-containing protein 63.
Protein: ACPS_BEUC1
Sequence: MIVGVGIDVVDVARFLAALDRSPRLRDRLFTPEERDLVGGSLAARFAAKEAIAKALGAPGGMRWHDATVARVPGGAPAVSLRGTVLAVADGLGITSWHLSLSHDAGIASAIAVAER
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_NITSB
Sequence: MDFLKNQDPAVYEIFEKELQRQTDHLEMIASENFTSPAVMEAMGSVFTNKYAEGYPGKRYYGGCEYADAIEELAIQRAKELFGCEFVNVQPHSGSQANQGVYLALLKPYDKILGMDLSHGGHLTHGAKVNASGKIYQSFFYGVNDEGWIDYDRVLDIAKIVKPKLIVCGASAYPRVIDFKKFREIADEVGALLMADIAHIAGLVAAGEHPSPFPYCDVVTTTTHKTLRGPRGGMIMTNDADIAKKINSAIFPGIQGGPLVHVIAAKAVGFGENLKPEWKEYAKQMRINASTLATVLMNRGYNVVSGGTDNHLVLVSFLDKDFSGKDADEALGRAGITVNKNTVPGETRSPFVTSGIRIGSPALTARGMKEAEFELIANKIADVLDNIHDVNLHEKIKEEMVALARKFVIYDRPTY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGM3_MOUSE
Sequence: MSALQIQNVNWQVPMNRRAHHTDKFSSQDSIVRRGQPWEIILVCNRSLESGEDLNFIVSTGPQPSESARTKAVFSISGRSTGGWNAALKANSGNNLAIAIASPVSAPIGLYTLSVEISSRGRASSLKLGTFIMLFNPWLQADDVFMSNHAERQEYVEEDSGIIYVGSTNRIGMVGWNFGQFEEDILNISLSILDRSLNFRRDPVTDVARRNDPKYVCRVLSAMINGNDDNGVISGNWSGNYTGGVDPRTWNGSVEILKNWKKSGFRPVQFGQCWVFAGTLNTVLRCLGVPSRVITNFNSAHDTDRNLSVDVYYDAMGNPLEKGSDSVWNFHVWNEGWFVRTDLGPTYNGWQVLDATPQERSQGVFQCGPASVNAIKAGDVDRNFDMIFIFAEVNADRITWIYNNRNNTQKQNSVDTHSIGKYISTKAVGSNSRMDVTDKYKYPEGSSEERQVHQKALDKLKPNASFGATSSRNPEGEDKEPSISGKFKVTGILAVGKEVSLSLMLKNMTNDRKTVTMNMTAWTIVYNGTLVHEVWKDSATISLDPEEEIQYPVKIAYSQYERYLKADNMIRITAVCKVPDEAEVVVERDVILDNPALTLEVLEQAHVRKPVNVQMLFSNPLDQPVNNCVLLVEGSGLLRGSLKIDVPSLRPKEKSRIRFEIFPTRSGTKQLLADFSCNKFPAIKAMLPIDVSE
What is the function of this protein?
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins.  Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes.  Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity).  In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, TG(E), TGE, TGase E, Transglutaminase-3, TGase-3.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_ACTSZ
Sequence: MQSSPLLENLVEHLRCLPGVGPKSAQRMAYHLLQRDRSGGMNLARALTDAMSKIGHCSQCRTFTEQETCAICDNPRRQHSGLLCVVEMPADIQAIEQTGQFSGRYFVLMGHLSPLDGIGPREIGLDLLQQRLQNEHFHEVILATNPTIEGDATANYIAEMCMQRNIKVSRIAHGIPVGGELETVDGTTLTHSFLGRRELG
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: QUEA_ECOBW
Sequence: MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSDL2_XENLA
Sequence: MLPNTGKLAGCTLFITGASRGIGKAIALKAARDGANIVVAAKTAEAHPKLPGTIYTAASEIEAAGGKALPCIVDVRDENQISAAVEKAVDAFGGIDILVNNASAISLTNTLETSMKKVDLMMGINTRGTYLTSKICIPYLKKSKVAHILNLSPPLNLNPMWFKNHCAYTIAKYGMSMCALGMSEEYKGEIAVNALWPKTAIHTAAMDMLGGSGVDKQCRKPDIMADAAYAILTKTKDFTGNFVIDEELLQQEGIKDLDVYAISPGHPLLPDFFLDESPETLASAMEEHGATAAFKAGKKQAKSQDASPLQETFKAIERSVNEEAVKSTQGIYQFVLSGEESGNWFLDLKNDKGGVGKGEPSTKADVVMSMDSGDFIKMFAGKMKPTMAFMSGKLKIKGDMGLALKLEKILGQMNAKL
What is the function of this protein?
Has apparently no steroid dehydrogenase activity.
What are the official names of this protein?
Hydroxysteroid dehydrogenase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ATP14_YEAST
Sequence: MFPIASRRILLNASVLPLRLCNRNFTTTRISYNVIQDLYLRELKDTKLAPSTLQDAEGNVKPWNPPQKPNLPELELQGPEALKAYTEQNVETAHVAKESEEGESEPIEEDWLVLDDAEETKESH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane.
What are the official names of this protein?
ATP synthase subunit H, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase h subunit family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: RL11_NEUCR
Sequence: MSTEQKAQNPMRELRIQKLVLNICVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKISVHVTVRGPKAEEILERGLKVKEYELRKRNFSETGNFGFGISEHIDLGIKYDPGIGIYGMDFYCCMTRPGERVSRRRRAKSRVGATHRITRDDTVKWFKSRFDAIVR
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LPXK_CHRVO
Sequence: MRLIEQHWYRPRGWLTALLAPLEGLFALLAAARRQAFRRGWKTSGRLPVPVVVIGNINVGGVGKTPLTLALLRDFAARGVKVGVISRGYGGKAPAPTEVGPDSDPALVGDEPLLLAAAGAPVVVGRDRVAAGRHLLARHPDVELILSDDGLQHYRLARDLEIVVLDGSRGLGSGRLLPNGPLREPPSRLAAVDAVVVNGEGAQLPLPDGLPRFAMTLRPGACHALDDASRARDAAGFAGRKVAALAGIGHPERFFDTLAGQGIAVEQRLSFPDHHAFVPGDIPADADAVIVTSKDAVKLARVIHDAAQRARLWVLPVQATLAPDLCEWILARLKTKHGR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RXLR3_PHYPR
Sequence: MRPPLLLFLTVTVLVSCASAVSTGNAAELRSLRSIKTTTNDDAAEEERGGFYHKFDLNFLDDIFHGLPEQFQRMRNQPERLRTMFENWKTGWMSVDDAVAYMTREGLSEKAISQFKAAYQAYLKHKG
What is the function of this protein?
Secreted effector that partially suppresses elicitor-induced cell death in host and enhances virulence of P. parasitica.
What are the official names of this protein?
Secreted RxLR effector protein 3.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: IBOD_AMAMK
Sequence: MIDRLIVAPPEFQIYRDEHGNRLPRPFGLPICLLFTYLCNTSAGYDLFRKPAFNTAMKTLLDSWGLYLTTKDSAKLLTDCEGGWFSEEALQEFESDSRGKFEETYVCPDPDAVNRGFSSWDAFFTREVQPNARPVEAPDDKSVIHNPCESYLHCIARDVKCHDLFWLKGNIYSLYDMLNRDHKLAKQFVGGTIYQGFLSPVDYHRWRSPVDGTIKKTEIVAGTYYAALPDAGAPEGNQYQAAGDLRGALKRSQTWLAMVAARALVYIEADNPDIGLVCFIAVGMVEVSTCEVTVKRGQKVSAGSELGMFHFGGSSFVLVFGPQACITFPEDVVLGKHVKLNSILARVHKA
What is the function of this protein?
Decarboxylase; part of the gene cluster that mediates the biosynthesis of the psychoactive metabolites ibotenic acid and muscimol (PubMed:32233056).  The first committed step is glutamate hydroxylation by the 2-oxoglutarate-dependent dioxygenase iboH, and the last step is decarboxylation of ibotenic acid to muscimol by the decarboxylase iboD (PubMed:32233056).  The order of the intermediate reactions is somewhat ambiguous (Probable).  IboA likely activates the carboxylic acid at position 5 to introduce an amide bond, and the flavin monooxygenase iboF generates the N-O bond (Probable).  There are several options for the latter step (Probable).  One option is that iboF directly hydroxylates the amide nitrogen formed by iboA to produce a hydroxamic acid species (Probable).  Another option is that iboF hydroxylates an external N-containing compound, whose resulting N-O bond is subsequently introduced into the hydroxyglutamate scaffold (Probable).  The paralogous PLP-dependent cystathionine gamma-synthase-like enzymes iboG1 and iboG2 are likely involved in substitution of the OH group at position 3 by the O-N moiety (Probable).  The first cyclic intermediate is most probably tricholomic acid which is likely desaturated to ibotenic acid by the cytochrome P450 monooxygenase iboC (Probable).
What are the official names of this protein?
Decarboxylase iboD, Ibotenic acid biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family.
Protein: TSAD_GLOC7
Sequence: MATILSIETSCDETAVAIVKNRNIYSNIVASQIDLHQTYGGVVPEVASRQHLETINPCLEQAFIEANLNWSDIDGIAATVAPGLIGALMVGVSAAKTLSILYQKPFIGVHHLEGHIYASYLSEPDLQPPFLCLLVSGGHTSLIYVKDCGIYEMLGSTRDDAAGEAFDKVARLLQLSYPGGPIIDRMAQTGNPHAFSLPEGRVSLPEGGYHPYDSSFSGLKTAVLRLVQKLEQDHLSLPVHDLAASFQETVARSLTKKTITCALDYNLTTIAVGGGVGANSALRKHLTSAATEHNLKVFFPPLKLCTDNAAMIGCAAADHFNRGHFSPLSIGVQSRLPITEVMKLYQ
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_BACFR
Sequence: MEENNNIYPIFDRMLTRQDKEELLKQRGVMIWFTGLSGSGKSTIAIALERELHKRGLLCRILDGDNIRTGINNNLSFSETDRVENIRRIAEVSKLFIDTGIITIAAFISPNNDIREMAARIVGPDDFLEIFVSTPLAECEKRDVKGLYAKARRGEIKNFTGISAPFEAPEHPALSLDTSVLSLEESVNRLLEIVLPRVSRHE
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.