PharMolix/UniProtQA huggingface dataset:
Protein: CK5P3_PONAB
Sequence: MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVLTIREKINAAIQDMPESEEIAQLLSGSYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAETGAAARQSLGEAIDVYQASVGFVCESHTEQVLPMLQFVQKRGNSTVYEWRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAKAAGIDWGIFPESDSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLARRAVELSEEADVLSVSQFQLAPAILQGQTKEKTVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPVNLMGTSL
What is the function of this protein?
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, in response to endoplasmic reticulum stress (By similarity).  Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation.  Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation.  Also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint.  Through its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation.  May also play a role in the rupture of the nuclear envelope during apoptosis.  May regulate MAPK14 activity by regulating its dephosphorylation by PPM1D/WIP1 (By similarity).  Required for liver development (By similarity).
What are the official names of this protein?
CDK5 regulatory subunit-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the CDK5RAP3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes and associates with microtubules.
Protein: YJ156_YEAST
Sequence: MLKIASLKKKDMQTKESCILKRPGLSCPPNKTKEVNESKQIFFLTWKNKATMKVSFIVAPTVMQVQCLFFFIL
What are the official names of this protein?
Putative uncharacterized protein YJL156W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MURG_RICBR
Sequence: MKKIVLVAGGTGGHFFPAVALGEELIKRKYEVHFITDLRCEKYINHDAGLIFHVIDLKRPKNILLFLPLLSLAIFKAIKLLFSLSPSAVVGFGGYPVVASMFAAIFLRVPIVIHEQNSYLGKVNRFFANFAKKIAISYKNTKNLPVVVKNRTVVTGGIVRKNIRGLDSVVKRRNDKDRTFKIFIFGGSQGAKLFSELIPESIKALMQKQPNLKLHITQQAALDDQVKIKNIYSNLNINYELAEFFDNMANQYKNTDLVISRAGASTIEELTYIGLPAIFIPLPSAADNHQYHNAKLLEDEKCGWCMKQDDISSEKLAEKIFELISNPKILENTSKNLLKRRKEGHKLLSNLIEELI
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNAK_EHRRW
Sequence: MILCRGLFMAVIGIDLGTTNSCVAVMEGGDAKAIENSEGARTTPSIVAFTDSEVLVGDPAKRQATTNAKNTIYASKRLIGRRYQDTRDIKTSYDIVSAKNGDAWIKVRDKDYSPSQIGALILEKMKETAERHLGCKVEKAVITVPAYFDDAQRQATKDAGRIAGLDVIRIINEPTAAALAYGLNKSDKQKVIAVYDLGGGTFDVSILEIADGVFEVKSTNGDTMLGGEDFDHAIMEYLMDDFKKSTGIDLHSDAMAMQRIKEAAEKAKIELSSRMETDINLPFLSSDSTGPKHLSLKLTRATFENLVSDLVKRTIEPCKKALKDAGISADKIDEVVLVGGMTRVPKIIQTVKEFFGKEPHKGVNPDEVVAIGAAIQGGILAGDVRDVLLLDVTPLSLGIETLGGVFTPLIERNTTIPTKKSQVFSTAEDGQTAVTIKVFQGERKMANDNKLLGQFSLEGIPPAPRGMPQIEVTFDIDANGIVHVSAKDKASGKEQAIRIQSSGGLTDDEIQNMIKEAESKAEEDEKRKKFVEVKNNAENLVHSTEKSLKEHGDKISNADKLDIENAIRDLKDCISKDNIEDTDTMQNKLDHLMKVSMKLGEALYSNTNNATAGDNNTTDTGSSSNSDGSKVVDSDYQEIDKKDGK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FTSQ_AGRFC
Sequence: MDGGGRFVFAVTGKKSTAKKREQYAATANADDRRVLPRPLRRFVRFGVSLATGRIHIPAHTGTISAVAFYAMIGLYGMSLGGHTNIVTQTTTSAAGFAVEDVKVSGNLQTSEIEVFQLLGLDGSTSLIALDIDAARRKLVQLPWVEDVDIRKVYPKTVEVRLKERQAFGIWQHGTELSLIEKSGSVIAPLRDNKFAALPLFVGRDAETGAAGFVAQLADWPEIRNRVRAYVRIAGRRWDLHLDNGIVVKLPEENLPQALQLLARLDLEEKVLSRDVAAVDLRLTDRTTIQLTEGAAERRQTAVDARTKALKKAEKNT
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: CPSF2_CAEEL
Sequence: MTSIIKLKVFSGAKDEGPLCYLLQVDGDYILLDCGWDERFGLQYFEELKPFIPKISAVLISHPDPLHLGGLPYLVSKCGLTAPVYATVPVYKMGQMFIYDMVYSHLDVEEFEHYTLDDVDTAFEKVEQVKYNQTVVLKGDSGVHFTALPAGHMLGGSIWRICRVTGEDIVYCVDFNHKKERHLNGCSFDNFNRPHLLITGAHHISLPQMRRKDRDEQLVTKILRTVRQKGDCMIVIDTAGRVLELAHLLDQLWSNADAGLSTYNLVMMSHVASSVVQFAKSQLEWMNEKLFKYDSSSARYNPFTLKHVTLCHSHQELMRVRSPKVVLCSSQDMESGFSRELFLDWCSDPRNGVILTARPASFTLAAKLVNMAERANDGVLKHEDRLISLVVKKRVALEGEELLEYKRRKAERDAEETRLRMERARRQAQANESDDSDDDDIAAPIVPRHSEKDFRSFDGSENDAHTFDIMAKWDNQQKASFFKTTKKSFPMFPYIEEKVKWDDYGEVIKPEDYTVISKIDLRKGQNKDEPVVVKKREEEEEVYNPNDHVEEMPTKCVEFKNRVEVSCRIEFIEYEGISDGESTKKLLAGLLPRQIIVVHGSRDDTRDLVAYFADSGFDTTMLKAPEAGALVDASVESFIYQVALSDALLADIQFKEVSEGNSLAWIDARVMEKEAIDNMLAVGTSNLMIDDKNREEDVNDQEENGATEGEGNAEPMEIGENGSQESLAISESGKEVENGHTNDSRTKKGTKGKIRGNLILDPLPKRLIPIHQAVFVNDPKLSDFKNLLTDKGYKAEFLSGTLLINGGNCSIRRNDTGVFQMEGAFTKDYYKLRRLFYDQFAVL
What is the function of this protein?
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition.
What are the official names of this protein?
Probable cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor 100 kDa subunit, CPSF 100 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS8_HELPS
Sequence: MVNDIIADSLTRLRNASMRRLEFTQLYYAKIVVSILEIFKEKGFIKDFNVKDKDKKQSVYVQLAYDEKGHSKISEVKRLSKPGRRVYKQKNELKRFKNGYGVIVVSTSKGVITNEEAYRQNVGGEVLCSIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: COQ7_ALBFT
Sequence: MPNTLQDRFFTTCDAALRTLFVTPHAERACPTLPGEATALTDAEKVQSGALMRVNHVGEVCAQALYTAQAFATKNEALRAHFTKASADETNHLAWTQQRLDELGARPSLLNPLWYGAAFGLGLLAGRLGDPISLGFVVETENQVEAHLESHLSLLPANDHASRAIVAQMKDDEVRHALDAQKAGAVPLPPPVKSLMTAAAKVMTTVAHRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PURR_VIBVU
Sequence: MATIKDVARLAGVSTTTVSHVINKTRFVAEATQEKVMKAVDELNYAPSAVARSLKCNTTRTIGMLVTQSTNLFFSEVIDGVESYCYRQGYTLILCNTGGIYEKQRDYIRMLAEKRVDGILVMCSDLTEELREMLDKHADIPKVIMDWGPISSQADKIIDNSEEGGYLATKYLIDNGHTKIACLSGHFEKAACQERIQGFKRAMKEANITLNNEWILEGNFECDTAVMAADKIASWQDRPTAVFCFNDTMALGLMSRLQQLGLRIPEDISVIGYDNIELAEYFSPPLTTIHQPKRRVGKNAFEILLERIKDKEHDKRVFEMHPELVVRDTVKKIN
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: PAND_BURM1
Sequence: MQRHMLKSKIHRAAVTHCELHYEGSCAIDEDLLEAANIVENERIDIWNINNGERFSTYAIKGERGSGMISLNGSAARRAQLGDLVIIAAFAMVEEAELQAGWKPKLVFIDEGNKIKGHRDHVPTQTWT
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OL147_MOUSE
Sequence: MISMLAGNGSSVTEFVLAGLTDRPELQLPLFYLFLIIYIITVVGNLGLIILIGLNPHLHTPMYYFLFNLSFIDLCYSSVFSPKMLINFVSEKNSISYAGCMTQLFLFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQICSVISFAAYGMGFAGSSAHTGCMLRLTFCNVNVINHYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRAKAFSTCSSHIMAISLFFGSAAFMYLKYSSGSMEQGKISSVFYTNVGPMLNPLIYSLRNKDVKVALRKSLIKFREKTDFN
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 147, Odorant receptor M3, Olfactory receptor 164-1, Olfactory receptor 7E.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAT4_ARATH
Sequence: MATKTDDFAPFPVKDQLPGVEFCVSSSPNWPEGIVLGFQHYIVMLGTTVIIPSILVPLMGGGDVEKAEVINTVLFVSGINTLLQSLFGSRLPVVMGASYAYLIPALYITFSYRFTYYLHPHLRFEETMRAIQGALIIASISHMIMGFFGLWRILVRFLSPLSAAPLVILTGVGLLAFAFPQLARCIEIGLPALIILIILSQYLPHLFKCKRSICEQFAVLFTIAIVWAYAEILTAAGAYDKRPDNTQLSCRTDRSGLISASPWVRIPYPLQWGRPSFHGSDAFAMMAATYVAIVETTGSFIAASRFGSATHIPPSVLSRGIGWQGIGVLLNGLFGTATGSTALVENTGLLGLTKVGSRRVVQISAGFMIFFSIFGKFGAVLASIPLPIFAALYCVLFAYVASAGLGLLQFCNLNSFRNKFILGFSIFIGLSVAQYFTEYLFISGRGPVHTRTSAFNVIMQVIFSSAATVGIMAAFLLDCTHSYGHASVRRDSGRHWWEKFRVYHTDTRTEEFYALPYNLNRFFPSF
What are the official names of this protein?
Nucleobase-ascorbate transporter 4, AtNAT4, AtPER.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: V1A14_RAT
Sequence: MMGVQICQGMMSEIPFFSPPPQFSYMMNKNIRLHTDSNIRNTFFTDIGIGISANSLLLLFNIFKLTRGQRSRLTDLPIGLLSLINLLMLLMAAFIATDTFISWKGWDDIICKFLVYLYRTFRGLSLCTSCLLSVLQAIILSPRSSCLAKFKHKPPHHISCAILSLSVLYMFIGSHLLVSIIATPNLTTNDFIHVTQSCSILPMSYLMQCMFSTLLAIRDVFLISLMVLSTWYMVALLCRHRKQTRHLQGTSLSPKASPEQRATRSILMLMSLFVLMSVFDSIVCSSRTMYLNDPISYSIQLFMVHIYATVSPFVFIVTEKHIVNFLRSVCEGDECLNIH
What is the function of this protein?
Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior.
What are the official names of this protein?
Vomeronasal type-1 receptor A14.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTP12_ARATH
Sequence: MESPESFSTMFMKPIRHILSEKKSRKIALFLLINTAYMVVEFVAGFMSNSLGLISDACHMLFDCAALAIGLYASYISRLPANHQYNYGRGRFEVLSGYVNAVFLVLVGALIVLESIERILDPQEISTNSLLVVSVGGLLVNIVGLIFFHEEHHHAHGGSGIFLHVLADTMGSVGVVISTLLIKYKGWLVADPASSIFISILIIASVIPLLRNSAEILLQRVPRAHRQDLKEAMRNILKTKGVCSIQRLHVWSFTNSDVVATLHLLVSADSDKTDTKLQVSRLLEDAGVKDWTLQVESVNS
What is the function of this protein?
Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.
What are the official names of this protein?
Metal tolerance protein 12, AtMTP12.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: SP01_SCEBO
Sequence: AYTGQTGAPWGLA
What is the function of this protein?
Serine protease.  Degrades fibrinogen.
What are the official names of this protein?
Serine proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRCB_SHEPW
Sequence: MNNVLFVALGGSIGAVLRYLISILMLQVFGSGFPFGTLMVNILGSFLMGVVYALGQVSEVSPEIKAFIGVGMLGALTTFSTFSNESLLLMQEGYLVKAILNVVVNVGVCIFVVYLGQQLVFSRY
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLIP2_ARATH
Sequence: MENSRSTLIIFFAYTTIILIGSINCRDNNNNNLVTNQSALFVFGDSVFDAGNNNYIDTLPSFRSNYWPYGQTTFKFPTGRVSDGRTIPDFIAEYAWLPLIPAYLQPSNGKNQFPYGVSFASAGAGALVGTFPGMVINLKSQLNNFKKVEKLLRSTLGEAQGKMVISRAVYLFHIGVNDYQYPFSTNSSIFQSSPQEIYVDFVVGNTTAVIKEVYKIGGRKFGFLNMGAYDCAPASLIIDQTKIGTCFKPVTELINLHNEKLESGLRRLERELSGFKYALHDYHTSLSVRMNNPSKYGFKEGKMACCGTGPLRGINTCGGRMGVSQSYELCEKVTDYLFFDHFHLTEKAHQQIAELIWSGPTNVTKPYNLQALFELN
What is the function of this protein?
Involved in the resistance to the necrotropic bacteria Erwinia carotovora, probably via negative regulation of auxin signaling.  Possesses lipase and antimicrobial activities, inhibiting germination of fungal spores (e. g.  Alternaria brassicicola).
What are the official names of this protein?
GDSL esterase/lipase 2, Extracellular lipase 2.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: COBQ_DESRM
Sequence: MALAKTIMIQGTSSHVGKSLLCTALCRIFKQDGFHVAPFKAQNMALNSYVTLTGGEIGRAQGAQAEAAGIAATVTMNPVLIKPKQDLNAQVVVLGKPLADMSARDYRANFLPKAVNLVGQCIEELRREFQVLVIEGAGSPAEINLKDRDIVNMRTAILADAPVILVADIDRGGVFASLVGTLELLEPHERQRVAGFIINKFRGDIELLKPGLEFLEQRTGKPVLGVIPYLHEHGIEQEDSVALEGNKNVSSGSEIDIAVVKLPRISNFTDFDLIGRVPGICLRFVCPGDPMGTPEAVILPGTKNTIEDLQYLKEKGTDQEIIELARKGIPVVGICGGYQMLGKMLYDPWGTEASLESITGLGLLDIETTFFKEKQTHRCKAKITCTELNWCGITNQEITGYEIHTGQVKLGREAKPLLQITQRSGNIVALPDGAVGNQGHIWGTHLHGLFDNKALLLSWVNSLRERKGLSRLTLAKLPDNREEKYDNLAEAVRHHLNMKQLHQMMGLGEGKP
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: PDS5_SCHPO
Sequence: MIKLQFQRNIVPTHDNPLTTSEILKRLRDLLGELTSLSQDTIDRDSVLPVARSLVNNNLLHHKDKGIRSYTLCCIVELLRLCAPDAPFTLSQLEDIFQVILKILSGLMNQESTYYPQIYEILESLSNVKSAVLIVDLPNAEEFLVNIFRLFFDLARKGTTKNVEFYMLDIINQLINEINTIPAAALNILFAQLISGKGVRQTIGSSDSTNHGPAFQLARNIFHDSADRLQRYVCQYFSDIIFDSRDSLSDSMTTPEFIFSHNLVLQLWKYAPTTLLNIIPQFENELQAEQTSVRLVAIETVGLMLQDNAIWSDYPRVWSAFCGRLNDKSVACRIKCIEVASNALQNSLATSEIIENVVQMLQSKLADTDEKVRVATLKTIEQLTFETFKMQFSVQALKLMGDRLRDRKLNVRLQAIRTLSQIYNRAYQDLIDGVEYSIQMFSWIPSSLLEVFYVNDETTNAAVEICMAELVLQYLSSDTQTRLNRLFLSIKYFSEKAMRVFILLLQRQVKYSELLNYYIECCKNYNGGVMDNDEESITNKLKKVIDIISSKSSNPTLTEATFRKFAELNDRQSYKMLLQTFSIKSEYQVVLKSIKYLFKRVSETLSTASLECFRIFVYRSALFAFNKSNVHEIIQLLNEPVKYHNFLKPSEALLQHLPLIHPNIYGEVVIEVENIIVSSGIESDPKVIKALSQFSKRKKNFSIQTTTAEILRKLCLHGTQEQAKQAATIIAITETKEFKLDMITNIVENLEYNGGLPVRLMTLGQLFLYTLEEVEKVADQVTEFLVKKVIQRFPEKYDDTHNDEEWCTYEKLDNLTMCKVLAIRVLVNRLRAAAGGTEALNIGAPIIKLLKVLLMADGELSPFKNTPKISRAYLRLTASKYFLKLCSIPFYAEHIDFSSYVQISLLCQDENFDVRNLFLTKLQKQLQLKKLPISYYPLLFLTAVDPEEEIKTKASIWIRSQVAFFQKTHDFTMEYVATYLIHLLSHHPDISSIESENSLDFIAYIRFYVDTVVNSENVPIVFHLMQRIKQSYDVIEDGNNYIYVLSDMAQKILQVKSQNFGWSLTTYPKQIKLPYEILRPIPSIDEKKRIFNKIFITPKMESQIEHAIRTPVSSFAKQTTNKHANLKQKKTHSSKSDKKSSRRRKNEKRRKLNEQNPNIRNVPERSSSRFQGIRINYSEAPSSSEEISEEEEEISEEDFDEIEDL
What is the function of this protein?
Required for the establishment and maintenance of sister chromatid cohesion during S phase.  Prevents their formation until eso1 is present.  May also have a role during meiosis.
What are the official names of this protein?
Sister chromatid cohesion protein pds5, Precocious dissociation of sisters protein 5.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localized to chromatin throughout the cell cycle.
Protein: AMPP1_COLGM
Sequence: MERIDTTGRLSRLRELMKERNVDVYVIPSEDSHASEYIAGCDARREFISGFSGSAGCAVVTLDKAALATDGRYFNQASKQLDQNWLLLKQGLQDVPTWQEWSAEQSAGGKVVGVDPELITGSIAKKLTEKVKRSGGSDLVPLDENLVDLVWAEARPARPKNPIKVLPEKFSGKDVKTKLKELRQELDRKNSRAFVVSMLDEIAWLFNLRGDDIPYNPVFFSYAIITSDSATLYVDASKLGEETRAYLADNDVCVKPYDIVFDSINTLRSSDTSCQTTSGVSSKRFMISTKASWALKRSLGGDSQVDEVRSPIGDSKAVKNKSEMAGMRACHIRDGAALIEYFAWLEDQLVAKKVKLDEVQAADKLEQLRSKQKDYVGLSFDTISSTGANAAVIHYKPERGACSIIDPTAIYLCDSGAQYLDGTTDTTRTLHFGQPTEAEKLAYTLVLKGNIALDTAIFPKGTTGFAIDCLARQHLWKEGLDYRHGTGHGVGSYLNVHEGPIGIGTRVQFAEVALAPGNVLSIEPGFYEDGSYGIRIENVAMVTEVKTKHSFGDKPYLGFEHVTMVPYCRNLIEPNLLTAEEKAWLNAHHADILQKTKGYFQDDPLTMTWLARETQPL
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: GLSA_CLOD6
Sequence: MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICIIDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMKLEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYKSEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGVDIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMGIGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: EFTS_MARSD
Sequence: MAITAQMVKALREKTGVGMMDCKKALAECDGNEENAIKYLREKGLAKAAKKAGRATSEGLVGTYTHSNGKLVAMVELKCETDFVAKAEQFIQLSKDLAMQVAATSPVCVKPEDLPQEMLEKEKEIYKQQAIAEGKPENIAEKIVEGRVNKYYKEVCLLEQPFIKDDKKTIKDLLNDTIAVLGENMQIGRFARINLAEAVAEESEAE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_STAS1
Sequence: MTQLITTIEEMRSIIANLHNQRRSVGFIPTMGALHDGHLKMMSLSLNENDVTIISIFVNPLQFGPNEDLDSYPRDIVGDTAKAESVGVDYIFHPTVKEMYPELPTIELKAGRLASVLEGAERPGHFDGVVTVVNKLFNIVRPHKAYFGKKDAQQLAIVEKMVEDFNHPIEIKGVDIVREDDGLAKSSRNIYLTKNERIEAVHLYKSLCLAQSLYKNGERNSEKIIKATRDYLTEHTSGTIETVAIYSYPELVEQTQIKDSIFISLAVKFSKARLIDNIIIEG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_HAEIE
Sequence: MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFAPTGIILSGSPESTTEENSPRAPEYVFNAGVPVLGVCYGMQTMAMQLGGLTETSDHREFGYASVSLENSTALFANLNDNLTASEPKLDVWMSHGDKVTRLPQNFQVTGTTPTCPIAAMSDESRRFYGVQFHPEVTHTKKGLELLTNFVVNICGCETKWTAENIIEDAVARIKEQVGDDEVILGLSGGVDSSVVALLLHRAIGKNLHCVFVDNGLLRLHEGDQVMEMFGDKFGLNITRVDAESRFLGELAGVSDPEAKRKIIGKVFVDVFDDESKKLTNVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMINRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRNSGWYEKTSQAFSVFLPVKSVGVMGDGRKYDWVISLRAVETIDFMTAHWAHLPYDLLGKVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RECF_MYCTU
Sequence: MYVRHLGLRDFRSWACVDLELHPGRTVFVGPNGYGKTNLIEALWYSTTLGSHRVSADLPLIRVGTDRAVISTIVVNDGRECAVDLEIATGRVNKARLNRSSVRSTRDVVGVLRAVLFAPEDLGLVRGDPADRRRYLDDLAIVRRPAIAAVRAEYERVLRQRTALLKSVPGARYRGDRGVFDTLEVWDSRLAEHGAELVAARIDLVNQLAPEVKKAYQLLAPESRSASIGYRASMDVTGPSEQSDIDRQLLAARLLAALAARRDAELERGVCLVGPHRDDLILRLGDQPAKGFASHGEAWSLAVALRLAAYQLLRVDGGEPVLLLDDVFAELDVMRRRALATAAESAEQVLVTAAVLEDIPAGWDARRVHIDVRADDTGSMSVVLP
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEA_ECOL6
Sequence: MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECTLAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLAASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEAGFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARLAADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRGLAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKDGYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF
What is the function of this protein?
Involved in the metabolic adaptation in response to environmental changes.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: FQR58_MYCTU
Sequence: MPLSGEYAPSPLDWSREQADTYMKSGGTEGTQLQGKPVILLTTVGAKTGKLRKTPLMRVEHDGQYAIVASLGGAPKNPVWYHNVVKNPRVELQDGTVTGDYDAREVFGDEKAIWWQRAVAVWPDYASYQTKTDRQIPVFVLTPVRAGG
What is the function of this protein?
Involved in a F420-dependent anti-oxidant mechanism that protects M. tuberculosis against oxidative stress and bactericidal agents.  Catalyzes the F420H(2)-dependent two-electron reduction of quinones to dihydroquinones, thereby preventing the formation of cytotoxic semiquinones obtained by the one-electron reduction pathway.  In vitro, catalyzes the reduction of menadione to menadiol; since menaquinone is the sole quinone electron carrier in the respiratory chain in M. tuberculosis, the physiological electron acceptor for Fqr-mediated F420H(2) oxidation is therefore likely to be the endogenous menaquinone found in the membrane fraction of M. tuberculosis.
What are the official names of this protein?
F420H(2)-dependent quinone reductase Rv1558, Fqr.
What is the protein family that this protein belongs to?
Belongs to the F420H(2)-dependent quinone reductase family.
Protein: LEUD_WOLSU
Sequence: MNIQQGKVWKFGENIDTDLIIAARYLNTSDPQVLASHVMEDARPDFLQHFTKGDFIVAGENFGCGSSREHAPVALKTAGVSAVIAKSFARIFYRNSFNTGLPILEVKETDEIREGDTLEVDMAQGTIKNLTRNQTYAFKPIPPFMMELLESGGLIEHAKAKIAQGVL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.