PharMolix/UniProtQA huggingface dataset:
Protein: ARGR_PHOLL
Sequence: MRTPSKQEDLVKAFKALLKEEKFSSQGEIVTALLEEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTATSPLKNLVLDVDYNHPIVVIRTSPGAAQLIARLLDSLGKSEGILGSIAGDDTIFVTLTRDSTTEQLRGAILGLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECA_MACBI
Sequence: ADTIVAVELDSYPNTDIGDPNYPHIGIDIKSIRSKSTARWNMQTGKVGTVHISYNSVAKRLSAVVSYTGSSSTTVSYDVDLNNVLPEWVRVGLSATTGLYKETNTILSWSFTSKLKTNSIADANSLHFTFNQFSQNPKDLILQGDATTDSDGNLELTKVSSSGDPQGNSVGRALFYAPVHIWEKSAVVASFDATFTFLIKSPDRDPADGITFFIANPDTSIPSGSGGRLLGLFPDAN
What is the function of this protein?
D-mannose/D-glucose-binding lectin.  Induces histamine release in mast cells from hamster and rat.  Induces lymphocyte proliferation and IFNG production.
What are the official names of this protein?
Lectin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: ZA1LS_XENLA
Sequence: MAGLVYPQYPVFPGYRQPYRQLPPFYKPKQPYWKPPYKGVPGPMKPTNPLDCLDGYKWAQLKALLSQLGPEFGLGRRFTKEVGVQVNPRVDACIQCSLGPRTLKNCKGGPFLFHAVPGQHAGLGIIAPVRFPRTTAVYSRLSDRRLFTLPTPTYGGKKEGGTQMDPVEEDLLLKRPTFQFLEQKYGFFQCKDCQIRWESAYVWCVSGTNKVYFKQFCHKCQKGHNPYYVESIECKRCKKAWCSCPERRHIDLKRPHCQDLCGRCKGQRLSCDKTFSFKYII
What is the function of this protein?
mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (PubMed:36278895).  Controls timing of meiosis during oogenesis (PubMed:36278895).  Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity).  Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation (PubMed:36278895).
What are the official names of this protein?
Protein ZAR1-like 1.S, Zygote arrest protein 1-like 1.S.
What is the protein family that this protein belongs to?
Belongs to the ZAR1 family.
Protein: CH603_TRIV2
Sequence: MVKTILYKDTARWTLEKGFDALTEAVAVTLGPKGRNIVLEKKFGAPQIVNDGVTIAKEIELEDPAENTGISLLRQAASKTNDVAGDGTTTAIVLAHAMLKEGLRNVTAGADPLTVKRGIDKATEFVIEKIQEHARPIKDSRDIEQVATISAGNDPEVGRIVAEAMERVGKEGVISLEEGRSTTTELEVTEGMRFDRGYVSPYFVTDPERMEAVLEEPHILITDRKITMVQDLVPILEQIARTGKPLLIIADDIEKEALATLVVNHLRGVLRVAAVKAPGFGAQRKAVLEDIAALTGGQVISEDTGLKLENVRLEMLGKARRAIVTKDDTTIVAEGNEEAVKARIEQIRRQIQEVESSYDKEKLQQRLAKLAGGVAVIKVGAATETELKDRKLRLEDAINATKAAVEEGIVPGGGTTIAHIAPQLEEWAKSQMKDEELTGTMIVARALYAPLRRIADNAGANGAVIVERVRELPFDEGYDAVANKFVNMFEAGIVDPAKVTRSALQNAASIGGMVLTTEGVVVEKPDKQAKAPAGVGPGPGEGFDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_SALDC
Sequence: MSDVTVVNCPTCGKPVVWGEISPFRPFCSKRCQLIDLGEWAAEEKRIASSGDQSDSDDWSEER
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: GUAA_ALISL
Sequence: MTTNIHAQRILILDFGSQYTQLVARRIREIGVYCELWSWDVEESDIRDFNPDGIILSGGPESVTEANSPRAPQYVFDSGVPVFGVCYGMQTMAEQLGGKVATSTEREFGYAAVQVTGESALFKDLEATQDVWMSHGDKVVEIPSDFVKIAETETCPYAAMANEEKKYYGVQFHPEVTHTKNGLKMLENFVLNVCGCEGLWTSASIIEDAIARIKEQVGDDEVILGLSGGVDSSVVAMLAHRAIGDKLTCVFVDNGLLRLNEAEQVMEMFSEGFGLKIIHVEAEERFLSALSGESDPEAKRKIIGHVFVDIFDEESKKLSNAKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHNADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGKVSNRIINEVGGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: Y092_CERSK
Sequence: MGLSLAAYAGAALAEIAGCFAVWAWWRLGASALWLVPGALSLGAFAWLLALTPVEVAGRSYAVYGGIYVAASLLWLWAVEGVRPDRWDMGGAALVLAGAAVILWAPRG
What are the official names of this protein?
UPF0060 membrane protein RSKD131_0092.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SURF6_HUMAN
Sequence: MASLLAKDAYLQSLAKKICSHSAPEQQARTRAGKTQGSETAGPPKKKRKKTQKKFRKREEKAAEHKAKSLGEKSPAASGARRPEAAKEEAAWASSSAGNPADGLATEPESVFALDVLRQRLHEKIQEARGQGSAKELSPAALEKRRRRKQERDRKKRKRKELRAKEKARKAEEATEAQEVVEATPEGACTEPREPPGLIFNKVEVSEDEPASKAQRRKEKRQRVKGNLTPLTGRNYRQLLERLQARQSRLDELRGQDEGKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRRWEKRTAGVVEKMQQRQDRRRQNLRRKKAARAERRLLRARKKGRILPQDLERAGLV
What is the function of this protein?
Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA.  May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly (By similarity).
What are the official names of this protein?
Surfeit locus protein 6.
What is the protein family that this protein belongs to?
Belongs to the SURF6 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Granular component of the nucleolus.
Protein: RL24_STAMF
Sequence: MAITYSSKPSKQRKALFNMPLHLRHKLFNAPLSKELREKYGVKKLPVRKGDVVRIMRGDWKGHEGKVVRIDLRRVRLYVEGVQRKKADQTPVYYPIHPSKVMIIKLDLSDKWRRKIIERRKGLIESEVVEEKETSKTSEGGGKTIEETEGEK
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ALXA_CAEEL
Sequence: MATFGFLSAPLKSTNEVDLVKPLTSYIDNVYNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALDVLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFNIGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLMPDTLAALSALMTAQAQEAIYIKGHKDKMKATSMVKISAQVAEFYSEAQKMMSKDIVRGLWDKDWSAIVSGKNLAYQALAQYHQSEVCGEARQIGEQLSRLAESLKLFDTAQKYLPRDITGIWDIYPSVSKAHAAAKKDNDFIYHEKVSDFRTLPTLPKAVLAKPTPMQTPMTPSFRDMFAVLVPVQVHNAMQSYDARKAELVNMETVRMREATQLMNGVLASLNLPAALDDVTSTETLPESLKLKSAKLKQNGGSSEIMRLFSELPTLYQRNEDILTETSRILNEEKESDDTMRKQLGTKWTRMSSEQLTGPLVTEIGKYRGILHTASNADKMVKEKFESHRQGIELLSKNESELRSSIPGQTAHATGETDTVRQLRQFMSQWNEVTTDRELLEKELKNTNCDIANDFLKAMAENQLINEEHISKEKIAQIFGDLKRRVQSSLDTQETLMNQIQAANNTFTGEKTGSSTGAERERILKMLAQASDAYVELKANLEEGTKFYNDLTPILVRLQQKVSDFAFARQTEKEDLMRQLQLSIVSGQAAKAVVDGVNSLVSSYLTGGTNAAQSPANAPPRPPPPRPAAPSVESPIPPPRTQQSMQATPGAPPQYNPYQQQQQPQMQQFQQHPGYYQQPMPYGQPQPMFQPQYQPTFAAPYPTFPGAFPSYQQQWPQQQQQGGFPPNPQFGQQNQQQGGGGGANPFQ
What is the function of this protein?
Required for lin-12 degradation after it has been internalised in the vulval precursor cells.
What are the official names of this protein?
Apoptosis-linked gene 2-interacting protein X 1, Prion-like-(Q/N-rich) domain-bearing protein 58, Protein YNK1.
Protein: RS2_DECAR
Sequence: MSVTMREMLEAGVHFGHQTRFWSPKMAPYIFGARNKIHIVNLEKTLAKYNEAMAFVKKLASSRGTILFVGTKRQAREIIGEEALRAGAPFVDQRWLGGMLTNFKTVKTSIKRLKDMEVAVEAGELEKMPKKEALTFRRELEKLQKSIGGIKEMAGLPDAIFVIDVGYHKIAITEAEKLGIPVIGVVDTNHSPDGVAYVIPGNDDSSRAIQLYARGVADAILEGRSQVVQDIVAAGGDDEFVEVQDAAQ
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RSMA_PROM9
Sequence: MNSKNYHQKKRFGQHWLVNKKILEKIKEIAVLNENDFILEIGPGKGALTSKLLDSEIKKLHAIELDKDLINLLNDKFNNNDKFSLQQGDILSVNLDSINKKITKVIANIPYNITGPILDIFIGRLGIIRNYNYEKIIFLMQKDVVDRILSKEGSPNAGALSIRIQLLSKIKRICDVPPSSFSPPPKVFSSLVVFEPIKNDLRLDISLEKYIDKLLRISFNSRRKMLRNTLNSILSNEEINELSESSKVCFNLRPQDISIHQWIKLAENCIKIKKKI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLC1_CITSI
Sequence: MSSCINPSTLATSVNGFKCLPLATNRAAIRIMAKNKPVQCLVSTKYDNLTVDRRSANYQPSIWDHDFLQSLNSNYTDETYKRRAEELKGKVKTAIKDVTEPLDQLELIDNLQRLGLAYHFEPEIRNILRNIHNHNKDYNWRKENLYATSLEFRLLRQHGYPVSQEVFSGFKDDKVGFICDDFKGILSLHEASYYSLEGESIMEEAWQFTSKHLKEMMITSNSKEEDVFVAEQAKRALELPLHWKAPMLEARWFIHVYEKREDKNHLLLELAKLEFNTLQAIYQEELKDISGWWKDTGLGEKLSFARNRLVASFLWSMGIAFEPQFAYCRRVLTISIALITVIDDIYDVYGTLDELEIFTDAVARWDINYALKHLPGYMKMCFLALYNFVNEFAYYVLKQQDFDMLLSIKHAWLGLIQAYLVEAKWYHSKYTPKLEEYLENGLVSITGPLIITISYLSGTNPIIKKELEFLESNPDIVHWSSKIFRLQDDLGTSSDEIQRGDVPKSIQCYMHETGASEEVAREHIKDMMRQMWKKVNAYTADKDSPLTRTTAEFLLNLVRMSHFMYLHGDGHGVQNQETIDVGFTLLFQPIPLEDKDMAFTASPGTKG
What is the function of this protein?
Catalyzes the conversion of geranyl diphosphate to (+)-(4R)-limonene (PubMed:28272875, PubMed:28272876).  Produces exclusively the (+)-enantiomer (PubMed:28272875).  Can use neryl diphosphate as substrate (PubMed:28272876).  Has no activity with farnesyl diphosphate (PubMed:28272875).
What are the official names of this protein?
(R)-limonene synthase 1, chloroplastic, (+)-limonene synthase 1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BGA13_ORYSJ
Sequence: MKTTMAAAATCLVALLVVVLAEAAGVGCTTVAYNDRSLVIDGERRIIISGSIHYPRSTPEMWPDLIKKAKEGGLDAIETYVFWNGHEPHRRQYNFEGNYDIIRFFKEIQNAGLYAILRIGPYICGEWNYGGLPAWLRDIPQMQFRMHNAPFENEMENFTTLIINKMKDANMFAGQGGPIILAQIENEYGNVMGQLNNNQSASEYIHWCADMANKQNVGVPWIMCQQDSDVPHNVVNTCNGFYCHDWFPNRTGIPKIWTENWTGWFKAWDKPDFHRSAEDIAFAVAMFFQKRGSLQNYYMYHGGTNFGRTSGGPYITTSYDYDAPLDEYGNLRQPKYGHLKDLHSVIKSIEKILVHGEYVDANYSDNVTVTKYTLGSTSACFINNRNDNKDLNVTLDGNTHLLPAWSVSILPDCKTVAFNSAKIKAQTTIMVKKANMVEKEPESLKWSWMRENLTPFMTDEKGSYRKNELLEQIVTSTDQSDYLWYRTSLDHKGEASYTLFVNTTGHELYAFVNGMLVGKNHSPNGHFVFQLESAVKLHDGKNYISLLSATIGLKNYGPLFEKMPAGIVGGPVKLIDNNGTGIDLSNSSWSYKAGLAGEYRQIHLDKPGYRWDNNNGTVPINRPFTWYKTTFQAPAGQDTVVVDLLGLNKGVAWVNGNNLGRYWPSYTAAEMGGCHHCDYRGVFQAEGDGQKCLTGCGEPSQRYYHVPRSFLKNGEPNTLILFEEAGGDPSQVIFHSVVAGSVCVSAEVGDAITLSCGQHSKTISTIDVTSFGVARGQCGAYEGGCESKAAYKAFTEACLGKESCTVQIINALTGSGCLSGVLTVQASC
What are the official names of this protein?
Beta-galactosidase 13, Lactase 13.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: MTNX_BACC0
Sequence: MSIQVFCDFDGTITNNDNIMSIMEKFAPPEAEEVKNRILSQELSIQEGVSQLFQLIPTNLHDEIIQFLIETAEIRNGFHEFIQFVNENNISFYVISGGMDFFVYPLLQGLIPKEQIYCNETDFSNEYITVNWPHPCDRLCQNHCGLCKSSLIRKLSDTNDFHIVIGDSITDLQAAKQADKVFARDFLITKCEENHISYTPFETFHDVKTELKHLLEVKL
What is the function of this protein?
Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase, HK-MTPenyl-1-P phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MtnX family.
Protein: HAL3A_ARATH
Sequence: MENGKRDRQDMEVNTTPRKPRVLLAASGSVAAIKFGNLCHCFTEWAEVRAVVTKSSLHFLDKLSLPQEVTLYTDEDEWSSWNKIGDPVLHIELRRWADVLVIAPLSANTLGKIAGGLCDNLLTCIIRAWDYTKPLFVAPAMNTLMWNNPFTERHLLSLDELGITLIPPIKKRLACGDYGNGAMAEPSLIYSTVRLFWESQAHQQTGGTS
What is the function of this protein?
Involved in plant growth, and salt and osmotic tolerance (PubMed:10652125).  Catalyzes the decarboxylation of 4'-phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis (PubMed:11279129, PubMed:11923307, PubMed:12860978, PubMed:16415216).  The enzyme is also able to decarboxylate pantothenoylcysteine to pantothenoylcysteamine (PubMed:11923307).
What are the official names of this protein?
Phosphopantothenoylcysteine decarboxylase, PPCDC, AtCoaC1, Halotolerance protein Hal3a, AtHal3a.
What is the protein family that this protein belongs to?
Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.
Protein: UBA2C_ARATH
Sequence: MDMMKKRKLDENGNGLNTNGGGTIGPTRLSPQDARKIIERFTTDQLLDLLQEAIVRHPDVLESVRLTADSDISQRKLFIRGLAADTTTEGLRSLFSSYGDLEEAIVILDKVTGKSKGYGFVTFMHVDGALLALKEPSKKIDGRVTVTQLAASGNQGTGSQIADISMRKIYVANVPFDMPADRLLNHFMAYGDVEEGPLGFDKVTGKSRGFALFVYKTAEGAQAALADPVKVIDGKHLNCKLAVDGKKGGKPGMPQAQDGGSGHGHVHGEGMGMVRPAGPYGAAGGISAYGGYSGGPPAHHMNSTHSSMGVGSAGYGGHYGGYGGPGGTGVYGGLGGGYGGPGTGSGQYRMPPSSMPGGGGYPESGHYGLSSSAGYPGQHHQAVGTSPVPRVPHGGMYPNGPPNY
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as component of a complex regulating the turnover of mRNAs in the nucleus.  Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs.  May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus (By similarity).
What are the official names of this protein?
UBP1-associated protein 2C.
Protein: HTPX_PEDPA
Sequence: MLYQQIASNKRKTVYVMIGFAILVLFIGAAVGYVFYDSAMAGIIMAAVIAAIYMAMMIANSTNVVMGMNHATEISEADHPEIWHIVEDMALVANIPMPKVYIVNDASPNAFATGNSPKNAAVAVTTGILERLNREELEGVIGHEVSHIRNYDIRLSTIALALSSAIAMLVNIGMRSFWWGGGRRRNDNDNEGGSLEIVMMIISIVLVILGPIATTIAQLALSRNREYLADASSVELTRNPLGLIHALQKISVSEPMKEADPSSAALYISDPFKKKRTMAHLFDTHPPIEDRIQRLERM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS20_NEIG2
Sequence: MANSAQARKRARQSVKQRAHNASLRTAFRTAVKKVLKAVEAGDKAAAQAVYQESVKVIDRIADKGVFHKNKAARHKSRLSAKVKALA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ILVD_BACHK
Sequence: MRSDMIKKGFDKAPHRSLLKATGLKDEDFDKPFIAICNSFIEIIPGHKHLNEFGKLVKEAVRAAGMVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVNAHWFDGMICIPNCDKITPGMMMAALRINIPTVFVSGGPMAAGKTSKGDVVDLSSVFEGVGAYQSGKISEEELKDIEDHGCPSCGSCSGMFTANSMNCLCEVLGLALPGNGSILAIDPRREELIKQAAEKLKILIERDIKPRDIVTEEAIDDAFALDMAMGGSTNTVLHTLALAQEAGLDYDMNRIDAVSRRVPHLCKVSPASNWHMEDIDRAGGISAILKEMSRKEGVLHLDRITATGQTLRENIAHAEIKDKEVIHSLENPHSEEGGLRILKGNLAKDGAVIKSGATEVKRFEGPCVIFNSQDEALAGIMLGKVKKGDVVIIRYEGPRGGPGMPEMLAPTSAIAGMGLGADVALLTDGRFSGASRGISVGHISPEAAAGGTIALLEQGDIVCIDVEERLLEVRVSDEELDKRKKEWKRPEPKVKTGWLGRYAQMVTSANTGAVLKIPNFD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: COFH_SYNE7
Sequence: MIDSATVAAILASVLDGKPLEPEAATVLLKARDRSLRQQIQAAANQLRSRQVGDRVSYVINRNLNFTNICEQHCNFCAFRRDADQDGAFWLDASILLEKGAAAVAAGATEFCLQGGLNPAAKRNGRSLDFYVELTASLKQAFPQIHLHAFSPQEIQFIAREDGLSFREVLMALRSAGVGSLPGTAAEVLDDSVRRILCPEKLDSATWKTIIQTAHQVGLPTTSTLLSGHLETPSQQAQHLEQLRQLQQAAIAGETPARITEFILLPFVGELAPAPLRKRVKRDQPDLSDALLVMAVARLYLGDWIANHQPSWVKLGLAGATQALDWGCNDLGGTLMEEHITSMAGAQGGTAQTVEQLEAAIAAAGRQPYQRDTLYRPVAVEAVHAG
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: UBIG_THIDA
Sequence: MSNVDAAEIAKFSELAHRWWDPNSEFKPLHEINPLRLRWVDTRAPLAGKKVLDVGCGGGILAEAMAGVGATVSGIDLSEKALKVARLHLYESGKSVDYELVSAEDYAAAHPGEFDVVTCMEMLEHVPDPASVVAACARLVKPGGWVFFSTLNRNAKSYLLAVVGAEYILKLLPRGTHDYAKFIKPAELARMAREAGLETEELTGMTYNPLTKVYRLEADTDVNYLMATRREA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: KTHY_KOSOT
Sequence: MFISFEGIDGSGKSTQVALFREYLERNSMEYVFIREPGGTQAGEDIREILLHNEYKLFPETELLLFMASRAQIVREVIIPALKKKKLVLADRFLDSSVAYQGYGRGLSIQMVTTLNEFSTGGVTPHLTLFIDVPVDVAVKRMRREMKHDKIEMESLDFFKRVRQGYLELAKRDPKRILVIDGTMSVEKIHEQVVKEFLLCLKKLGHGL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: Y7832_ORYSJ
Sequence: MAAAAAPLADDGDGIVDRDMWLACAAPNSGRLPAVGSVVFYFVDGHAAQFCQFPAPLLEQLAVPGPRVFLCTVAAVRLRADALTNEAYAEITLDPVADHDVPRLAPAPAPAPAAAAGGQQLRYFVKTLMISDFDFRIRFSAPMADAKGVFPPLVDAKAVQPLLVKDLHGSPMTFDYGRKGKRVTLAKVWKKFRDDMDFVDGDSVIFMRRRDDDDDDGELYVGVRRQRTLERPLRNTMRRYRPPTPPQAAVQEAVLAAAGHAAAGERFTVAYRSRKDGDEFVVPREAVEEGLRARLTSLAEVEFVWAVEDGAPPIVGPRGKVTAIATGQLWRNLEIVWDGNSEMDMSANFWQVRPVEEVDISPSTPPPKRLKNCEIDDTASTSVSVDNGDEQVPTMRQRLEALIPDNI
What are the official names of this protein?
B3 domain-containing protein Os07g0183200.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURB_RHILW
Sequence: MKQVNGEKLLASLGDGVKDIRGRITPDAPMDRVTWFRAGGLAELMFQPHDIDDLVAFLKILPEEVPLTVIGVGSNILVRDGGIPGVVLRLSAKGFGFVELAGENRILAGSICPDKHVAAMAMDNGIGGFHFFYGIPGSIGGAARMNAGANGVETRERLIEVNAVDRKGNKHVLSNAEMGYSYRHSTASSELIFTSVLFEGYPEERAQIRAEMDAVRNHRETVQPVREKTGGSTFKNPAGHSAWKLIDEAGCRGLVIGGAQMSSLHCNFMINMGQATGYDLEYLGEQVRREVFEKEGIKLEWEIKRLGVFMPGREVRPFHGVTSE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT2A2_HUMAN
Sequence: MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS
What is the function of this protein?
Involved in the regulation of the contraction/relaxation cycle.  Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation.  Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca(2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca(2+) signaling cascades that promote osteoclast differentiation and activation.
What are the official names of this protein?
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GCN5_ARATH
Sequence: MDSHSSHLNAANRSRSSQTPSPSHSASASVTSSLHKRKLAATTAANAAASEDHAPPSSSFPPSSFSADTRDGALTSNDELESISARGADTDSDPDESEDIVVDDDEDEFAPEQDQDSSIRTFTAARLDSSSGVNGSSRNTKLKTESSTVKLESSDGGKDGGSSVVGTGVSGTVGGSSISGLVPKDESVKVLAENFQTSGAYIAREEALKREEQAGRLKFVCYSNDSIDEHMMCLIGLKNIFARQLPNMPKEYIVRLLMDRKHKSVMVLRGNLVVGGITYRPYHSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARDVDGLTHFLTYADNNAVGYFVKQGFTKEIYLEKDVWHGFIKDYDGGLLMECKIDPKLPYTDLSSMIRQQRKAIDERIRELSNCQNVYPKIEFLKNEAGIPRKIIKVEEIRGLREAGWTPDQWGHTRFKLFNGSADMVTNQKQLNALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHFHSKVQAGLQSGAKSQ
What is the function of this protein?
Acetylates histone H3 and ADA2 proteins in vitro.  Acetylates 'Lys-14' of histone H3.  Acetylation of histones gives a specific tag for epigenetic transcription activation.  Operates in concert with certain DNA-binding transcriptional activators.  Acts via the formation of large multiprotein complexes that modify the chromatin (By similarity).
What are the official names of this protein?
Histone acetyltransferase GCN5, AtGCN5, BIG TOP protein.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GCN5 subfamily.
What are the subcellular locations of this protein?
Nucleus.