PharMolix/UniProtQA huggingface dataset:
Protein: NRAM_I79A0
Sequence: MNPNQKIITIGSVSLTIATICFLMQIAILVTTVTLHFKQYECSSPPNNQVMPCEPIIIERNITEIVYLTNTTIDKEICPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGGIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRTPYRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGYDKNATASFIYDGRLVDSIGSWSKNILRTQESECVCINGTCTVVMTDGSASERADTKILFIEEGKIVHISPLSGSAQHVEECSCYPRYPGVRCVCRDNWKGSNRPVVDINVKDYSIVSSYVCSGLVGDTPRKNDRSSSSYCRNPNNEKGNHGVKGWAFDDGNDVWMGRTISEESRSGYETFKVIGGWSTPNSKLQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: SCPA_STRR6
Sequence: MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVSTLQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLLGEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHTTILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELILVQEESFGDIYLMEKKEESQVPQS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: FTMH_NEOFI
Sequence: MTIATEISCPEEEAFQLLDKYSWFPNDDQRRWWEYTGPNLLKLLRDAQYPQKDQISCLYLLQQLLVPYLGTFPVAGQAPLPWWSNVTTYGVPFELSWNLLHNIVRIGFEPLSHLAESGVDAFNKIAPEECLSRLACLDNTIDLARFRHFQHQLLVTPDEERRLLEEKGPLPKSGRGQQALAVEFQNGGISAKAYFFPGMKSLATGLSPGKLILDSIESLALPGLKEPVHHLCNSLGLQDDGHPTDTAIAPFLLGVDLCTPERSRLKFYVTDQVVSWDRVADMWTLRGKRLEDPQCADGLTLLRKLWDLLEIPEGYRSNIRPDFAFGTPPPEDYRPVMMANWTLSPKKKFPDPQIYLLTVGMNDAVVMDALVAFYEVLGWTDLASTYKDKVASY
What is the function of this protein?
12-alpha,13-alpha-dihydroxyfumitremorgin C prenyltransferase; part of the gene cluster that mediates the biosynthesis of fumitremorgins, indole alkaloids that carry not only intriguing chemical structures, but also interesting biological and pharmacological activities (PubMed:23109474).  The biosynthesis of fumitremorgin-type alkaloids begins by condensation of the two amino acids L-tryptophan and L-proline to brevianamide F, catalyzed by the non-ribosomal peptide synthetase ftmPS/ftmA (By similarity).  Brevianamide F is then prenylated by the prenyltransferase ftmPT1/ftmB in the presence of dimethylallyl diphosphate, resulting in the formation of tryprostatin B (By similarity).  The three cytochrome P450 monooxygenases, ftmP450-1/ftmC, ftmP450-2/ftmE and ftmP450-3/FtmG, are responsible for the conversion of tryprostatin B to 6-hydroxytryprostatin B, tryprostatin A to fumitremorgin C and fumitremorgin C to 12,13-dihydroxyfumitremorgin C, respectively (By similarity).  The putative methyltransferase ftmMT/ftmD is expected for the conversion of 6-hydroxytryprostatin B to tryprostatin A (By similarity).  FtmPT2/FtmH catalyzes the prenylation of 12,13-dihydroxyfumitre-morgin C in the presence of dimethylallyl diphosphate, resulting in the formation of fumitremorgin B (By similarity).  Fumitremorgin B is further converted to verruculogen by ftmOx1/ftmF via the insertion of an endoperoxide bond between the two prenyl moieties (By similarity).  Finally, verruculogen is further converted to fumitremorgin A by the verruculogen prenyltransferase ftmPT3 (PubMed:23109474).
What are the official names of this protein?
12-alpha,13-alpha-dihydroxyfumitremorgin C prenyltransferase, Fumitremorgin biosynthesis protein H.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: RL9_RHIE6
Sequence: MEVILLERISKLGQMGETVKVRDGFARNYLLPLGKALRANAANKARFESERATLEARNLERKSEAQKVADVLDGKSFIVVRSAGETGQLYGSVAARDVVEVLAAEGFNIGRNQVHLNTPIKAIGLHKVELQLHAEVEIHVELNVARSAEEAERQAKGEELTSVDAIYGVDEDALRPEDFFDPEADGIDEDEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RLMKL_SODGM
Sequence: MNSLFATTAQGLEELLRSELETLGAASCKVALGGVHFQADSRLLYRALLWSRLASRIVLPLNVFSVGSDGDLYRGVQAVDWPSLFTVDKRFAVYFSGTNAAIRNSQYGALKVKDAIVDSFTRHGARRPDVDRQQPDIRIQAYLHRDQVMLSLDLSGSSLHQRGYRGAAGQAPLKENLAVAIVLRSGWKPGTPLLDPMCGSGTLLIEAAMIAADCAPGLTRPYWGFSAWSGHDEAQWQESLDEARARTQTGLAQTSSRFYGFDIDGRVLEKARHNARRAGVAALITFQTGEVAQLINPLPEGQRGTVVSNPPYGERLESEPALIALHNQLGRVMKSQFGGWRLSLFSASPALLGALMLRAERSFSAKNGPLDCEQKNYLLAETATAPGSVEGQIATDFANRLRKNVRSLQKWVEREKLDCYRLYDADLPEYNVAIDRYSSWVVIQEYVAPKSVDPERARQRLYDVINATLAVLAIPASRLVVKARERQKGKSQYEKLAQKGEFLLVEEYGAKLWVNLTDYLDTGLFIDHRIARRMLGEMSRGKDFLNLFAYTGSASVHAGIGGACSTTSVDMSRTYLEWAEKNLRSNGLVGRQHRLIQADCLAWLAMAQETFDVIFIDPPTFSNSKRMADTFDVQRDHLALMAQLKRLLRPGGTLMFSNNKRGFQLDEAGLAALGLRAQSITDRTRSPDFAHNRQIHLCWLISHADKDTFKSCH
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIP_PLAFO
Sequence: MKQIRPYILLLIVSLLKFISAVDSNIEGPVIGIDLGTTYSCVGVFKNGRVEILNNELGNRITPSYVSFVDGERKVGEAAKLEATLHPTQTVFDVKRLIGRKFDDQEVVKDRSLLPYEIVNNQGKPNIKVQIKDKDTTFAPEQISAMVLEKMKEIAQSFLGKPVKNAVVTVPAYFNDAQRQATKDAGTIAGLNIVRIINEPTAAALAYGLDKKEETSILVYDLGGGTFDVSILVIDNGVFEVYATAGNTHLGGEDFDQRVMDYFIKMFKKKNNIDLRTDKRAIQKLRKEVEIAKRNLSVVHSTQIEIEDIVEGHNFSETLTRAKFEELNDDLFRETLEPVKKVLDDAKYEKSKIDEIVLVGGSTRIPKIQQIIKEFFNGKEPNRGINPDEAVAYGAAIQAGIILGEELQDVVLLDVTPLTLGIETVGGIMTQLIKRNTVIPTKKSQTFSTYQDNQPAVLIQVFEGERALTKDNHLLGKFELSGIPPAQRGVPKIEVTFTVDKNGILHVEAEDKGTGKSRGITITNDKGRLSKEQIEKMINDAEKFADEDKNLREKVEAKNNLDNYIQSMKATVEDKDKLADKIEKEDKNTILSAVKDAEDWLNNNSNADSEALKQKLKDLEAVCQPIIVKLYGQPGGPSPQPSGDEDVDSDEL
What is the function of this protein?
Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen.  Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity).  Acts as a key repressor of the unfolded protein response (UPR) (By similarity).
What are the official names of this protein?
Endoplasmic reticulum chaperone BIP, 78 kDa glucose-regulated protein homolog, GRP-78 homolog, Pfgrp, Binding-immunoglobulin protein homolog, BiP, Heat shock protein 70-2, Pfhsp70-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: GEP3_YEASZ
Sequence: MLNLCHALRGVRQFSCSVIVKVKCASCSIKLQDQDPSKPGYYTKPKSLPDSKLNPDLQDLKYLLFSQDIQLSKQAIQNDPDLKTKRDLLLRVICKRCSNALHHNNYNPEEFPESTLNDILNYVPRGSNVMHIVPFVEFPLHLDPNVLKRNDLDTTLVLTKSDQVFKDKNAVSKKVPIFMKQFLKNTLRIDSNKTFAISALKNWNISMFYNYFKNYTYLLGNPNVGKSTLINTLLQKYLGYKVKIDSTGKINSPSEEVMQEAFTNPKNFFKIQAAGVSHIPNLTRSVQAYQVGGKILFDLPGYSTSTSRLRLEEPIDERWLQRLRKTDLFNRKHIKQKTYESMKGTSQGGCYTVGGIFYLVPPKGSINQIVKYIPGPSKTFKNIEKGIDVFNSCNSSSGTHPLSRYCGIKSVICEKSQYKRYAIPPFIGSIEIVLKDIGYILLRTTGRYEFKGLHEIWIPRGIQVGIREPLENLIESGYRRYIETNGKESSCPRDRPIISSLYEMAPDEADTLNAVKKSYLEKTEKDLSARRFVDDDPYDLVQHLXKKKNPYWYYQW
What is the function of this protein?
Interacts genetically with prohibitins and thus may be involved in the mitochondrial lipid metabolism.
What are the official names of this protein?
Genetic interactor of prohibitins 3, mitochondrial, Altered inheritance of mitochondria protein 40, Found in mitochondrial proteome protein 38.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CHL1_ARATH
Sequence: MSSASSSSAASLLLGREVDVFLSFCCQTSHGYFQNILIRNGIRTFLSYRCLEKRFGPIGQRTLKALEESRVAVVMTSTTKPCSVGFLEELLVILEFQEKGSLMVIPIFLTDLSFNVEEICRQHPEKAPSWRTALTKLTNLAAEYPLSQNLAGMDQSDLLNQIARDISLVVFYSGSNDSNALVAMDRHMKVVYDLLALEVNKEVRTIGIWGSAGVGKTTLARYIYAEIFVNFQTHVFLDNVENMKDKLLKFEGEEDPTVIISSYHDGHEITEARRKHRKILLIADDVNNMEQGKWIIEYANWFAPGSRVILISQNKNLLVDAGVMDVYEVRSLRYDEALQVFSHFAFKQPYPPSDFEELAVRAVHLAGFLPLGLRLLGSFLAGKGREEWVAALLKLKAKQGGHIMEVWKLMEATDDKGLEEWETAADIVERKESSQDKSQQESEVAADILIGKESSQDKQ
What is the function of this protein?
Confers resistance to low temperatures by limiting chloroplast damage and cell death, thus maintaining growth homeostasis.
What are the official names of this protein?
Disease resistance protein CHL1, Protein CHILLING SENSITIVE 1-LIKE 1, CHS1-LIKE 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCDA_AGARV
Sequence: MMKLFKKKDKNIEAEETLAKNAESEKTAADGKNAGVAQETKEDAPETIVCPKCGKTVLKSVVKQHKYVCYECNYYFRVRAKNRIRMVSDKEAFEPWFTELTTGNPLNFPEYEEKIAKTQEKTGLSEGIVIGKTKIYGEETVLGVIDSRFMMGSMGHVVGEKITSAFERATEERLPVILFCCSGGARMQEGIISLMQMAKTSAAAKRHSEAGLLYVPVLTDPTTGGVTASFAMLGDIILAEPKALIGFAGPRVIEQTIGQKLPEGFQRAEFQLEHGFVDMIVEREDLKKTLYKILRAHRPTTGYANFDPLHSDDNYEPTELMKEREAKAKPFKVWDKVSAARQIKRLASVDYMDYIFDEFMELHGDRYFRDDPAIVGGIAYLDGQPVTVIGVHKGKDLEDCAKRNYGMPSPEGYRKALRLMKQAEKFNRPIITFVNTSGAYPGMEAEENGQGEAIARNLYEMSGIKVPILCLMIGEGGSGGALALSVGNEVWMMENATYSILSPEGFASILWKDGKRAKEAAEVMKITAHDLKELDVVDDIIPEFGGADEDALSSIGNYMKGNMKKFLEKESKLTKDQLLEERYKRFRKF
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity).
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha, ACCase subunits beta/alpha, Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_BURMA
Sequence: MSVADIKKSEVVAQFARGANDTGSPEVQVALLTARITELTGHFKTHAKDHHSRRGLLRMVSRRRKLLDYLKGKDADRYRALIEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HAK10_ORYSJ
Sequence: MKSPSPVDPESPSSPDCKGGSSSKRRRLPWRMTMSLAYQSLGVVYGDLSTSPLYVYKAAFAEDIQHSETNEEILGVLSFVFWTLTLVPLLKYVCVVLRADDNGEGGTFALYSLLCRHARAALLPPGGGGGGGEPGDEDQFLDAGADKKAAANGNALALSGRGGGGGAAAGVRRLLERHKVLQRVLLVLALVGTCMVIGDGVLTPAISVFSAVSGLELSMEKHQHKYVEVPIACFVLVCLFCLQHYGTHRVGFLFAPIVITWLLCISMIGVYNIVHWEPNVYRALSPYYMYKFLKKTQRGGWMSLGGILLCITGSEAMFADLGHFNQLSIQIAFTCMVYPSLILAYMGQAAYLCKHHIIESDYRIGFYVSVPEKIRWPVLAIAILAAVVGSQAVITGTFSMIKQCTALGCFPRVKIVHTSDKVHGQIYIPEINWILMILCLAITIGFRDTKHLGNASGLAVITVMLVTTCLMSLVIVLCWHKSIFLAFGFIIFFGTIEALYFSASLIKFREGAWVPIVLAFIFMAIMCIWHYGTIKKYEFDLQNKVSINWLLGLSPNLGIVRVRGIGLIHTELDSGIPAIFSHFVTNLPAFHQVLIFLCIKNVPIPHVSPEERFLVGRIGPKEYRIYRCIVRYGYHDVHKDDQEFEKELVCSVAEFIRSGAAAAADAAASSKPKNVCGGGAEESEKEEEERMSVIPSGSIRMMEEDGGAGAPSSEDTVGGSGSGSGRGSSRGGGGAREIMSPSPSPPPVVVAPRKRVRFVLPAASPRPDAGVREELQELMDAREAGMAFILGHSYVKAKSGSSFFRRLVINFCYDFLRRNSRGPNYAVTIPHASTLEVGMIYYV
What is the function of this protein?
High-affinity potassium transporter.
What are the official names of this protein?
Potassium transporter 10, OsHAK10.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=May localize to tonoplast.
Protein: PQQE_XANC8
Sequence: MSTVPPPLSVLLELTHRCPLACPYCSNPIALAALREEMDTAGWRSLLEQAAEMGVLQAHFSGGEPMLRKDLPELVAHARALGLYSNLITSGVAGGEPMLDQLQAAGLEHVQLSVQDVDPAGADHIAGYRNSLSKKRAFAAAVRARGLPLTLNAVIHRHNAERVPGMIALALEWGAERIEVAHTQYYGWGLRNRAALMPSREQLAATIVAVETARRSLGDQLAIDFVTPDYYARQPKPCMGGWAQRFVNISPRGDVLPCHAAETIDGLQFDNLRDRSLADIWNHGEAFARFRGTAWMPEVCQGCPKREIDWGGCRCQALALAGDAATLDPVCERSPAHAGIRATAEREAASPAPDFVYRRPERPAAVAAEAAISDTE
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: EFG_DINSH
Sequence: MARDYPLDRYRNFGIMAHIDAGKTTCSERILYYTGKSHNIGEVHDGAATMDWMEQEQERGITITSAATTTFWERTEDGETADTPKHRLNIIDTPGHVDFTIEVERSLAVLDGAVCVLDANAGVEPQTETVWRQADRYKVPRIVFVNKMDKIGADFFNCVHMIEDRTGARAVPVAIPIGSENELEGLVDLVTMQEWVYKGDDLGASWVKGEIRDSLKDVCEEWRGKMIEAAVEEDDDAMMEYLEGNEPDVPTLRALLRKGTLALHFVPVLGGSAFKNKGVQPLLNAVIDYLPSPLDVVDYMGFAPGDENEERNIPRRADDDMPFSGLAFKIMNDPFVGSLTFTRIYSGTMNKGDTVLNSTKGKKERIGRMMMMHSNNREEIEEAFAGDIIALAGLKDTTTGDTLCDVKEPVVLETMTFPDPVIEIAVEPKTKNDQEKMSQGLARLAAEDPSFRVETDIESGQTIMKGMGELHLDILVDRLKREFKVEANIGAPQVAYRETIGHEVEHTYTHKKQSGGSGQFAEVKLVISPTEPGEGYSFESKIVGGAVPKEYIPGVEKGIKSVMDSGPLAGFPVIDFKVALVDGKFHDVDSSVLAFEIAARMGMREGMKKAGAKLLEPVMKVEVVTPEEYTGGIIGDLTSRRGQVTGQEPRGNAVAINAFVPLANMFGYINTLRSMSSGRAQFTMQFDHYDPVPANISQEIQEKFA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVA_STAAC
Sequence: MTVKTTVSTKDIDEAFLRLKDIVKETPLQLDHYLSQKYDCKVYLKREDLQWVRSFKLRGAYNAISVLSDEAKSKGITCASAGNHAQGVAYTAKKLNLNAVIFMPVTTPLQKVNQVKFFGNSNVEVVLTGDTFDHCLAEALTYTSEHQMNFIDPFNNVHTISGQGTLAKEMLEQAKSDNVNFDYLFAAIGGGGLISGISTYFKTYSPTTKIIGVEPSGASSMYESVVVNNQVVTLPNIDKFVDGASVARVGDITFEIAKENVDDYVQVDEGAVCSTILDMYSKQAIVAEPAGALSVSALENYKDHIKGKTVVCVISGGNNDINRMKEIEERSLLYEEMKHYFILNFPQRPGALREFVNDVLGPQDDITKFEYLKKSSQNTGTVIIGIQLKDHDDLIQLKQRVNHFDPSNIYINENKMLYSLLI
What is the function of this protein?
Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction.  The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate).  Both intermediates are unstable and short-lived.  The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia.  In the low water environment of the cell, the second step is accelerated by RidA (By similarity).
What are the official names of this protein?
L-threonine dehydratase biosynthetic IlvA, Threonine deaminase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: TA1_ARATH
Sequence: MENIKNPKNADDCSDSISKNSHQGVDDSLNQSRSYVCSFCIRGFSNAQALGGHMNIHRRDRAKLRQKLMEDNKDDVVAESDASEVVSLDLNEQQQQQGEALTCDDHDQYVDNDISPKQKLEFWVQESKLDTNDHGKVTEASIDGSSSSHHRDIEVLDLELRLGQSVVKKKTT
What is the function of this protein?
Activation factor which mediates telomerase activity and potentiates responses to auxin through the regulation of BT2.  Binds in vitro to the DNA sequence 5'-GACAGTGTTAC-3' of the BT2 promoter.
What are the official names of this protein?
Transcriptional regulator TAC1, Protein TELOMERASE ACTIVATOR1.
What are the subcellular locations of this protein?
Nucleus.
Protein: IOLE_GEOKA
Sequence: MEKTVNPFRIGIAPISWVNDDIPGLGDHYTQDQVLSEMAELGYVATEMGRLFSQDPPSLRAKLNQYGIELASKFIGVLFSDRSRLEEELKTFRSWAEYLHDMGCKYAIVCEMGGSMHWDPRRAPEEKTIQRLTDSEWESLVDGLHRAAHICQELGMKLVYHFHAGTVVETAEEIDRLMELTDPNLVHLLYDTGHALYGGYDPVELLHRYADRIQYVHLKDVRHDVLELVRREQLDFRTAVLRGMFTVPGDGCIDFVPIFAKLIEMDYNGWIIVEAEQDPAVAHPYTYAKMAKEYIDRLVHHLLAAQKR
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: HIP5_ARATH
Sequence: MGEVQEGPKVEQEKKPAATVVPVETTDGKPKSGGGDSAAAAAPPVAAVVSAFVYKVDMHCEGCAKKIKRMVKHFDGVKDVTADTGGNKLLVVGKIDPVKLQEKLEEKTKRKVVLANPPPKVEGPVAAAVGEKKADGGDKEAAPPAPAPAAPKESVVPLKIRLHCEGCIQKIKKIILKIKGVETVAIDGAKDVVTVKGTIDVKELVPLLTKKLKRTVEPLVPAKKDDGAAENKKTEAAAPDAKKEAPSAGVNEAKKEGSDGGEKKKEVGDGGEKKKEGGDGGEKKKEAGDGGEKKKDGGGVPAPVAMVNKMDYYGYSAYPTAPMHWQEGHVYGQSYSMTGQNYPVGGQSYPGSGYNYASESYVPYAQPNVNAPGMFSDENPNGCSVM
What is the function of this protein?
Heavy-metal-binding protein (By similarity).  Involved in disease resistance (PubMed:12684538).
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 5, AtHIP05, Farnesylated protein 2, AtFP2.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: RBM7_MOUSE
Sequence: MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKLKQFAFVNFKHEVSVPYAMNLLNGIKLFGRPIKIQFRSGSSHASQDASVSYPQHHVGNLSPTSTSPNSYERTVGNVSPTAQMVQRSFSSPEDYQRQAVMNSVFRQMSYAGKFGSPHADQLGFSPSAQPHGHTFNQSSSSQWRQDALSSQRKRQNSHPYLADRHYSREQRYSDHGSDYHYRGSREDFYYDDRNHDGWSHDYDNRRDSSRGGKWPSSRH
What is the function of this protein?
RNA-binding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation.  NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs.  Binds preferentially polyuridine sequences and associates with newly synthesized RNAs, including pre-mRNAs and short-lived exosome substrates such as promoter upstream transcripts (PROMPTs), enhancer RNAs (eRNAs), and 3'-extended products from small nuclear RNAs (snRNAs).  Participates in several biological processes including DNA damage response (DDR) and stress response.  During stress response, activation of the p38MAPK-MK2 pathway decreases RBM7-RNA-binding and subsequently the RNA exosome degradation activities, thereby modulating the turnover of non-coding transcriptome.  Participates in DNA damage response (DDR), through its interaction with MEPCE and LARP7, the core subunits of 7SK snRNP complex, that release the positive transcription elongation factor b (P-TEFb) complex from the 7SK snRNP.  In turn, activation of P-TEFb complex induces the transcription of P-TEFb-dependent DDR genes to promote cell viability.
What are the official names of this protein?
RNA-binding protein 7, RNA-binding motif protein 7.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus. Note=Excluded from the nucleolus.
Protein: PFMAA_PESFW
Sequence: MTADIRVSIDRGGTFCDVIAHVEGREPIIFKLLSVDPANYQDAPTEGIRRVLEIVEGKKIPVGEKLDGTRIASCRLGTTVATNALLEGKYEKFALVTTKGFEDVCVIGDQSRPKLFDLKVKKAEALHDTVIGVDERVTIEDYDLNPYPLDKSASLNDPDLVRTPSGEIIRILARVNEETVREQLLALRDAGYNSVAISFMHSYIFPDHEDQVAKIAREVGFTYVTTSAETRPVLKYLNRSTSCCSEACLYPVIRRYIENFESGFRVLPRRVDFMCSDGGLKQSQKFRGNEALLSGPAGGVVGIATSCYDVEQKIPIIGFDMGGTSTDVSRFDGKYDYLSETVIADRTISMPMLNISTVAAGGGSILFARSGLLVVGPESAGAHPGPACYRKGGPLTVTDANLFLGRLVVSSFPSIFGENADQPLDQDVVTAKFQEITADFNSQTSQNLTAEEVALGFLDVANEAMSRPIRNTTEARGFAPEKHNLVSFGGAGGQHACAIASKLGIKRVLIHKWSSLLSAHGISQADLQYESFEPLSLDFGMDLNGFIKERLSLLREKVAAGLLAQGAQESTLRFDESLVMKYFGTDTTITVTTPDDLDYGAAFEALHLREFAFKLNRKIVIDSVNVRGTGSAVTLATEEPPLKALARVKSVATTAQTTEEQKVYINGSWRKVPIYRLDQLSKGCAVSGPAMIIDKTQTIFVEPRFNAYILPDHVILEESNVEDTVTRQAVSAEEINPLLLSVFAHRFMSIAEQMGNTLQRTSVSSSIKERLDFSCAIFSREGKLVANAPHIPIHLGSMQMAIRYQHEAWKGKLKPGDALVTNHPLSGGTHLPDLTVVSPVFVNGDVAFYVASRGHHTDIGGKGIAAMMPESKELWEEGISIKTMKIVSGGEFLEDEIRAAFDKAGSFPGCSPTRRIADNLSDLKAQIASNQRGIILLGNLCEEFTLPVVCTYMEGIQANAEFAVRRFLKQLAKKHPEPLTAIDYFDDGTPIKIKIIIDPETGGAVYDFSGTGPQQWGNYNCPISITHSAIIYTLRCLVDVDIPLNEGCLTPIDIRVPYGSMLNPSPAVAICGSTLASQRVIDTILRAFRRCAASQGCASSFSWGMGGRDPETGKVLPGWNYGESLGGGVGALPGYHGESAINVHSTNTRNTDPEVVEKRTAVLVTKYAVRKGSGGRGQWRGGDGVTREIQARIPLKFSILSDRRVYRPYGMEGGEAGHRGQNYVFKFNQEGTGFEQINLGGKAVVVLNPGEKMQINTPGGGAWGKPEGDADGYREEDQAGDGI
What is the function of this protein?
5-oxoprolinase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment forming a dark layer in the conidial wall that protects the conidia from UV radiations (PubMed:28517364).  The first step of the pathway is the production of the pentaketide 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN or T4HN) by the polyketide synthase PfmaE though condensation of acetyl-CoA with malonyl-CoA.  T4HN is not stable and easily oxidizes into the stable form flaviolin (PubMed:28517364).  T4HN is also substrate of the hydroxynaphthalene reductase PfmaG to yield scytalone (PubMed:28517364).  The scytalone dehydratase PfmaJ then reduces scytalone to 1,3,8-THN (PubMed:31116900).  1,3,8-THN is then substrate of the hydroxynaphthalene reductase PfmaI to yield vermelone (Probable).  Vermelone is further converted by the multicopper oxidase PfmaD to 1,8-DHN (Probable).  Finally the laccase PFICI_06862 transforms 1,8-DHN to DHN-melanin (Probable).  The roles of the 5-oxoprolinase PfmaA and the proline iminopeptidase PfmaB within the cluster have not been elucidated yet (Probable).
What are the official names of this protein?
5-oxoprolinase PfmaA, Conidial pigment biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the oxoprolinase family.
Protein: ECOT2_LEIMA
Sequence: MPAGMSDAAGKTLADFKAPYPEPTSQQRRYVIFLDPKGDSKELNDYKVELIPGRVEKVDGTNVYRMGGNIEERTIDGWGYPYYIVTLTTMSGTLMMPLGDAALKRPRFVAMNTKNLYRYNSRLPIVVYMPKDGELRYRIWTVKSTGSGTAKSTKAREM
What are the official names of this protein?
Ecotin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.