PharMolix/UniProtQA huggingface dataset:
Protein: ADH_MYCTU
Sequence: MSDGAVVRALVLEAPRRLVVRQYRLPRIGDDDALVRVEACGLCGTDHEQYTGELAGGFAFVPGHETVGTIAAIGPRAEQRWGVSAGDRVAVEVFQSCRQCANCRGGEYRRCVRHGLADMYGFIPVDREPGLWGGYAEYQYLAPDSMVLRVAGDLSPEVATLFNPLGAGIRWGVTIPETKPGDVVAVLGPGIRGLCAAAAAKGAGAGFVMVTGLGPRDADRLALAAQFGADLAVDVAIDDPVAALTEQTGGLADVVVDVTAKAPAAFAQAIALARPAGTVVVAGTRGVGSGAPGFSPDVVVFKELRVLGALGVDATAYRAALDLLVSGRYPFASLPRRCVRLEGAEDLLATMAGERDGVPPIHGVLTP
What are the official names of this protein?
Probable alcohol dehydrogenase adh.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: LPXH_STRM5
Sequence: MTTLFISDLHLDPSRPEITDLFLRFLREQAPTADALYILGDLFEAWIGDDTPSPAADAVADALKVLTDSGVPAYFIRGNRDFLLGEDYARRAGLRILPDPCVIELYGRPVLLQHGDLLCTDDIPYQQFRAQTRDPAFQAQFLSQPLAARIAFAQKARETSQARQSEMKQGDRATFENVTDVAPAEVDATFVRHGVDTMIHGHTHRPAIHALQAGGRACTRIVLGDWYEQGSVLRVDANGWTLDTLSRE
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GATA_THEVB
Sequence: MSVIQELHRQLVRKERSATEITQAYLDRIAQVEPTLHSFLTVTRDRALAQAAEVDKRLAAGEEIGLLTGIPLAIKDNLCTYGVRTTCASKMLEHFVPPYESTVTEKLQAAGAIMVGKTNLDEFAMGSSTENSAFGFTANPWNPERVSGGSSGGSAAAVAARECAAALGSDTGGSIRQPAAFCGVVGLKPTYGLVSRYGLVAYASSLDQIGPLAPTVTDAAILLGAIAGHDPKDATSLRVPIPDYTQALKPDLKGMRIGLIQETVGEGVQPEVKSALEAALKTLEALGATLVELSCPRFAYGLPTYYIIAPSEASANLARYDGVNFGFRAEGASDLLEMYMKTRAQGFGAEVKRRIMIGTYALSAGYYDAYYLRAQKVRTLIKEDFARAFEQVDVLICPTAPTTAFKAGEKTADPLSMYLSDLMTIPVNLAGLPGLSVPCGFDSNGLPIGLQLIGNVLQEATLFHVAYAYEQTTPWHQQQPQL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ESP1_MOUSE
Sequence: MTSLPVLLFLIILLLPSMITEGRVLTQTGKEATIFADQKTNHEADLKNPDPQEVQRALARILCALGELDKLVKDQANAGQQEFKLPKDFTGRSKCRSLGRIK
What is the function of this protein?
Male-specific phermone which is recognized by the Vmn2r116/V2rp5 receptor in the vomeronasal organ (VNO) and enhances female sexual receptive behavior (lordosis) upon male mounting, resulting in successful copulation.
What are the official names of this protein?
Exocrine gland-secreted peptide 1.
What is the protein family that this protein belongs to?
Belongs to the exocrine gland-secreted peptide family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted by the extraorbital lacrimal gland into tears.
Protein: ST15B_HUMAN
Sequence: MGVVLSPHPAPSRREPLAPLAPGTRPGWSPAVSGSSRSALRPSTAGPGPGPGTGWGGTAASGRWVPAPAVHCAAPRAAAGHQQHHGPPLCSPDGAPRRFKRRPGSPAPAAQTGETSLREQPHGGPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGDACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALCRTTEP
What are the official names of this protein?
Synaptotagmin-15B.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
Protein: ENO_NEIMB
Sequence: MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFALDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIEDGMDENDWEGWKLLTEKLGGRVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPSKAAFYQLGK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ATPL_WOLPP
Sequence: MDLVALKFIAIGLAVFGMLGAGLGIANIFSAMLNGIARNPESEGKMKSYVYIGAAMVEIMGLLAFVLAMLLIFAA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL34_MANSM
Sequence: MKRTFQPSVLKRSRTHGFRARMATKNGRQVLARRRAKGRKSLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: HPDA_CLODC
Sequence: MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANPESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECVNSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKCHEVNIHTAIETSACVSNEVFNKIFKDIDFAFIDIKHMDREKHKEQTGVYNDLILENISNLANSDWNGRLVLRVPVISGFNDSAENISDIISFMHKNNLIEINLLPFHRLGESKWIQLGKEYEYSDKGDIDEEHLEELQDIFLDNGIACYVGHETAF
What is the function of this protein?
Catalyzes activation of 4-hydroxyphenylacetate decarboxylase under anaerobic conditions by generation of an organic free radical on a glycine residue, via a homolytic cleavage of S-adenosyl-L-methionine (SAM).
What are the official names of this protein?
4-hydroxyphenylacetate decarboxylase activating enzyme, Hpd-AE.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
Protein: Y1261_SYNY3
Sequence: MASSTQTNVTIAPKTLQQLRQQDAVILVDVREPLEFVGEHITDAYSLPLSRLNPSQLPQAEGKTTVLYCQSSNRSGNALQQLRSAGVEGIIHLEGGLLAWKQAGLPTVKTKNAPISIMRQVQIIAGSLVLTGVLLGSFVAPGFYFLSGFVGAGLLFAGLSGTCMMANLLGKLPYNQIKD
What are the official names of this protein?
Uncharacterized protein slr1261.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YRAN_SHIBS
Sequence: MATVPTRSGSPRQLTTKQTGDAWEVQARRWLEGKGLRFVAANVNERGGEIDLIMREGWTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: SAPC1_MOUSE
Sequence: MESPGPGGPPLVQAPYTVLLLPLGTSRQDPGAQNFFLWLQMMQALEREQDALWQGLELLEHGQAWFADRLRETQQRQLQLGALGEDFLMDLHSETDAPLLTRIQKVNACLHSLIHKELSKHRKGVTQSTGEVVSQAPPGPKGPTLV
What are the official names of this protein?
Suppressor APC domain-containing protein 1, Protein G7d.
Protein: RT11_HUMAN
Sequence: MQAVRNAGSRFLRSWTWPQTAGRVVARTPAGTICTGARQLQDAAAKQKVEQNAAPSHTKFSIYPPIPGEESSLRWAGKKFEEIPIAHIKASHNNTQIQVVSASNEPLAFASCGTEGFRNAKKGTGIAAQTAGIAAAARAKQKGVIHIRVVVKGLGPGRLSAMHGLIMGGLEVISITDNTPIPHNGCRPRKARKL
What are the official names of this protein?
28S ribosomal protein S11, mitochondrial, MRP-S11, S11mt, Cervical cancer proto-oncogene 2 protein, HCC-2, Mitochondrial small ribosomal subunit protein uS11m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MNMG_DELAS
Sequence: MLYPQEFDVIVVGGGHAGTEAALAAARMGCRTLLLSHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMALATDIGGIQFRILNSSKGPAVRATRAQADRILYKAAIRDMLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGVRFRSRTVVLTAGTFLDGKIHVGLNNYAAGRAGDPPAVSLSSRLKELQLPQGRLKTGTPPRLDGRSIDFSQCEEQPGDGMPGGVNEGVLPVFSFIGNAAMHPRQMPCWITHTNERTHDIIRSGFDRSPMFTGKIEGVGPRYCPSVEDKINRFADKESHQIFLEPEGLTTNEFYPNGISTSLPFDIQYELVRSMKGLENAHILRPGYAIEYDYFDPRSLKSSFETRQIQGLFFAGQINGTTGYEEAAAQGLFAGLNAALQCRGQEAWLPRRDEAYLGVLVDDLITKGVTEPYRMFTSRAEFRLQLREDNADMRLTEAGRAMGLVDDARWDAFSRKRDAVSRETERLKSTWVNPRIVTPEESERVLGKSIEREYNLFDLLRRPDVGYGKLMSLNEGRYASADVQPDVLGDLSASVVEQVEIAAKYAGYIDRQKDEVQRAAHFENLRLPAELDYMQVPALSFEVRQSLQKHRPETLGQASRMSGVTPAAISLLMVHLKKGGFRGFAPDVTDAKGEEASA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5MAT2_SALSN
Sequence: MNINQINTKLIKPITPTPQNLKNYHISFLDQHVVKKYIAVVLYYQSAPDNGRLEDSLAETLVHFYPLAGRYIKTDLTVDCSDQGAEFIEAEARGDVRVTDLIGKTDTIHLCPEQYFGLDEGVDDPLLSIQVTRFSCGGATIAVSVSHRVFDVSSLETFLSAWSSASKTGGGVAPVIPSFALASLLPNKDEKFGLDSNKCQGKEQKIAVKRLLFEKRALTRLTSERTSGVRAACAVIAKALIRLDRTTHGKSRDFVVFQPINMRGRTGVPSPKNACGNMSFGSFTRRVSAKEEVGIGELVGLIGDGVRRGIAEYTEILCPDRDGRDVIIHVRNKNIKEVFKSETFVVSFTDWSKFGFYEVDFGWGRPIWSGVGPQRPRGNQTIMMRSKEGDGIEAWVHLNEDDMDLFEQDVEIKLFLS
What is the function of this protein?
Catalyzes the transfer of the malonyl group from malonyl-CoA to the 4'''-hydroxyl group of the 5-glucosyl moiety of anthocyanins.  Anthocyanins are ubiquitous colored pigments that are responsible for petal color.
What are the official names of this protein?
Pelargonidin 3-O-(6-caffeoylglucoside) 5-O-(6-O-malonylglucoside) 4'''-malonyltransferase, Anthocyanin 5-O-glucoside-4'''-O-malonyltransferase 2, Ss5MaT2.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: TRUA_THEP3
Sequence: MRNVMIVVEYDGTNYHGWQYQKNAVTVQEVLQKAIKKVTGEEVNLIGASRTDTGVHALYQVANFKTNTKIPAEKLPYALNSVLPDDIVVVQAKDVEDSFHARYSAKRKRYKYIILNRKFQMPTMRNYCWHISYPLNIEEMKKAASYLIGTHDFSAFKASGSSKTSTIRTVYDLTIEKNEDFINIEIEANGFLYNMVRIIVGTLSYVGLGKIKEDEVYDILKSKDRTKAGITAPPQGLYLIKIIY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TRUD_PSE14
Sequence: MNELELLGPRAYGDALGRAALKATAEDFQVDEVLDIPLSGDGEHLWLWVEKRGLNTEEAARRLARAAGVQLRTVSYAGLKDRQALTRQWFSIQLPGKADPDLSAAQDDTLQILKSTRHKRKLQRGAHAANGFTLRLTQLDADTDALNQRLEIIARQGIPNYFGTQRFGYQGGNLGEARDYAARKALPEQRAVRSRLLSTARSYLFNRVLAARVADGSWEKAQVGDLLAFTDSRSFFPAGVDECSDPRLAILDLHPTGPQWGEGHSPAGGATAELENAIANDESALREWLVRAGMEHERRILRLPIGRLTWHYPESDILQLEFVLPPGCFATVLVRELIDLVPVGQTDSPCVF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: SYDND_CHLAB
Sequence: MKYRTHRCNELSLSNVGERVRLSGWVHRYRNHGGVVFIDLRDRFGITQIVCREDEKPELHQLVDSVRSEWVLSIEGTVCRRLEGMENANLATGEIEVDIEKVDILSKAKNLPFSISDDHIHVNEELRLEYRYLDMRRGQILDRLVHRHKVMMACRQYMDKQGFTEVVTPILGKSTPEGARDYLVPSRIYPGSFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQPEFAQIDIEMSFGTPNDLFPIIEQLVVEMFAVQGIKIDLPLPRMTYQEAKDLYGTDKPDLRFGLQLHDCREHAKEFSFSIFLDQLAQGGTIKGFCVPGGADMSRKQLDVYTEFVKRYGAMGLVWIKKQESGIASNVAKFASEAVFQAMFADFGAQNNDILLLIAAPEDVANQSLDHLRRLIAKERNFYNEAQYNFVWITDFPLFAKEDGKICSEHHPFTSPLDEDIPLLDKDPLSVRSSSYDLVLNGYEIASGSQRIHNADLQNKIFSILELSPESIKEKFDFFIDALSFGTPPHLGIALGLDRIMMVLTGAEGIREVIAFPKTQKAADLMMDAPAEIMTSQLKELSIKVTS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_CHLCH
Sequence: MKRTFQPHNRKRRNKHGFRQRMATKNGRKVLSARRAKGRHSLSVSSDMVRH
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: WHAMM_MOUSE
Sequence: MDSEQPDSLDGWVPLREDLFPEPERHQLRFLVAWNAAKGQFAVTCHDRTAQRRRRERREAGDGGCSWAGVLSPAGFRGAHRQLAALWPALEPCFPPLPPELDAASGAGWGLGRGLWALLWPLLWPAPADPGDSALQELCRQLEHYLGLAAEGCGGATVRDVLFPAPGDSADCEGLSEFRERTLRARLGQTATRLHQVLQDHGKANTMVALMKVYQEEDELYQELVTMATTFFQYLLQPFRDMREVATSCKLGILKSLDEDELGPRRVAALQKEASEWTRQAEEAVGSIQDITVNYFKETVTALTGMQKQMEQDQKRFGQAAWATAMPRLENLKLMLARETLQLMRAKELCLKHRQAEIQRKVEDLPRQGKQLDVVDELEIQCYEIQLELYDVKLEMLRNEETILVTRLDSVKRLITEKQAEVIYYDPCESPEELQSLAPDLELHLGDNRELRALSQQCQRLEAQRGRICSRRALLRNRKDHCRENHQLRLQQAKQSLRHLHQHHSIQMKRDKVKEEEQKKKEWIDHERQKTLERLRAYKEKCPAHRSALKTTCSESMVSNLPGGRSQKRLSTAHHHKTAHPASSKTGSAVPLPEASVRPPEHQDPCGSVPVQAFVPVSDQTLSGSSEDLSLPPQPPAPPLPPPPPPPPPPPLPPALSSFQGTTHQNLGLRTLATEDRPLPLACDPSAGRPCDYQGPGSMDEVLASLRQGKASLRKVETPTLPHPGTSVNEQVLAAIRQGVQLKKVHTGQGVDPGKKSTSDLERSIREALERIKKVSADSEEDNDEPSPTEWDR
What is the function of this protein?
Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes.  Involved as a regulator of Golgi positioning and morphology.  Its activity in membrane tubulation requires F-actin and interaction with microtubules.  Proposed to use coordinated actin-nucleating and microtubule-binding activities of distinct WHAMM molecules to drive membrane tubule elongation; when MT-bound can recruit and remodel membrane vesicles but is prevented to activate the Arp2/3 complex.  Required for RhoD-dependent actin reorganization such as in cell adhesion and cell migration (By similarity).  Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.
What are the official names of this protein?
WASP homolog-associated protein with actin, membranes and microtubules, WAS protein homology region 2 domain-containing protein 1, WH2 domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle membrane. Golgi apparatus, cis-Golgi network. Note=Localized to a perinuclear compartment near the microtubule-organizing center (MTOC). Also detected on tubulo-vesicular structures in the cell periphery that frequently localized along microtubules.
Protein: GDF11_HUMAN
Sequence: MVLAAPLLLGFLLLALELRPRGEAAEGPAAAAAAAAAAAAAGVGGERSSRPAPSVAPEPDGCPVCVWRQHSRELRLESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
What is the function of this protein?
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development.  May play critical roles in patterning both mesodermal and neural tissues (By similarity).  It is required for proper vertebral patterning and orofacial development (PubMed:31215115).  Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634).
What are the official names of this protein?
Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOF_MARMS
Sequence: MKLASNTPDWVLAALEERRQQDLMRRTITLDSPQIPHTQIHSQDYTAFCSNDYLGLANHPKLIKALNDTAQAYGVGGGSSHLVCGHLAPHQALEEALADWLGYERVMLFSTGYMANLGVISALADKNRPIVQDKLNHASLIDGALLAQAPLRRYLHGDVASAQKLIARSAAGGLLITDGVFSMDGDIAPLTELSQLANQHDWMFMVDDAHGLGCLGENGRGCLALEGLDATSLPILVGTLGKAFGTAGAFVATSNDYADYLTQFARPYVYTTAMSPAIAGATLASLQLIQSAEGQERRDRLARHITYFRQRVQMLPVALMPSNTAIQPIVIGDSKAAIEISEQLKTLGIWCTAIRPPTVPAGSARLRITLSAAHSDEDLVLLCDSLEKVLTAKLLNAKRLNLK
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: MUKF_SHIBS
Sequence: MSEFSQTVPELVAWARKNDFSISLQVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALRDEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RS15_BURM9
Sequence: MSVADIKKSEVVAQFARGANDTGSPEVQVALLTARITELTGHFKTHAKDHHSRRGLLRMVSRRRKLLDYLKGKDADRYRALIEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ALB2_LATSA
Sequence: TKPGYINAAFRSSKNNEAYFFINDKYVLLDYAPGSSRDKVLYGPTPVRDGFKSLNQTIFGSYGIDCSFDTENNEAFIFYENFCALIDYAPHSKKDKIILGPKKIADVFPFFEGTVFESGIDAAYRSTRGKEVYLFKGDQYARIDYGSNSMVNKEIKSISSGYPCFRNTIFESGADAAFASHKTNEVYFFKDDHYARVKVTPGGKLAIMDGVREIVDYWPSLKDIVPL
What is the function of this protein?
May play a role in response to oxidative stress and polyamine biosynthesis.  The monomeric form binds one hemin per monomer.  In the dimeric form, about half of the dimers bind one molecule of spermine each under physiological conditions.  Ligand binding is mutually exclusive as binding of hemin leads to dissociation of the dimer.
What are the official names of this protein?
Albumin-2, 24 kDa albumin, LS-24, PA2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RPOZ_GEOMG
Sequence: MARVTVEDCLEKVDNRFLLVMLASKRVKQLYKGASPLIDNKAANKNVVVSLREIASGKVGYELTSRKAK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: URK_YERPS
Sequence: MTDKAHQCVIIGIAGASASGKSLIASTLYRELREQVGDQHIGVIPEDGYYKDQSHLSMEERVKTNYDHPSAMDHNLLLEHLQALKAGKPVELPLYSYTEHTRKKETVHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PME47_ARATH
Sequence: MQTHSSSLVFLALLCLSWALLVSPTRPPSQPPSHPPIQPSSQPPTQPPSQPPTQPPTQPPSHPPTQPPTPPPSQSPSQPSPLPPNIACKSTPYPKLCRTILSAVKSSPSDPYHYGKFTMKQCLKQARRLSKVINRFAQRVEADPGTSTVEEVSAVADCGELAELSVEYLETVTEELKAAELMTAALVDRVTSLLGGVVTNQQTCLDGLVDAKSGFATAIGTPLGNLTRLYSVSLGLVSHALNRNLKRYKGSKGKIFGGGNKPVREPLETLIKVLRKTCDKGKDCRKANRNLGELGETSGGSILVREAVTVGPYETDNFPTITEAVAAAPNHTFPEQGYFVIYARAGLYEEYVVISNKKRNIMLIGDGINKTIISGNHSFIDGWTTYNSSTFAVVGDRFVAVDVTFRNTAGPEKHQAVAVRNNADGSTFYRCSFEGYQDTLYVHSLRQFYRECDIYGTIDFIFGNAAAIFQNCNIYARKPMANQKNAVTAHGRTDPNQKTGISIINCTIGAAPDLAADPKSTMTFLGRPWKPYSRTVYIQSYISDVVQPVGWLEWNGTTGLDTISYGEYDNFGPGADTSKRVQWSGYSLLNLVQAMNFTVYNFTLGDTWLPQTDIPFYGGLLHTE
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor 47.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: Y8387_DICDI
Sequence: MEAKTQFELITIKSEDGFDENELSVLLKSDSDFHMNGFIWGHLAAKHVYSKLNSKLKSFEPKSRSEINEMIKAITAVTEFIEVHYYHEEEIAWKFLIEQQQCLSEPLLTIVKPQHTQWTEINNEMKDLVKSLTENQEIKDKSSNGWTESISKVKEILQKLTAMVYKSFYDEERIIIPVVLSSIPKSKQNKLGEKMNETMKNAPTSKFVLGAILDVCKTNKDLDENVKKAIPWAVRKVIFPLALEKNYNWFSEFVEIK
What are the official names of this protein?
Uncharacterized protein DDB_G0283871.
Protein: ACDH2_AZOVD
Sequence: MKKLKVAIVGSGNIGTDLMIKILRHGQHLEMGALVGIDPDSDGLARAARLGVATTAEGVEGLARLPGFGEIDFVFDATSAAAHVKNDPFLRGLRPGLRLIDLTPAAVGPYCVPVVNLEQNLREPNVNMVTCGGQATIPMVAAVSRVARVHYAEIVASIASRSAGPGTRANIDEFTETTSKAIEAIGGARKGKAIIVLNPAEPPLIMRDTVYVLSAPADQARVEASLAEMAQAVQGYVPGYRLKQRVQFDEIPDAAPLNIPGLGRLSGLKTSVFLEVEGAAHYLPAYAGNLDIMTSAALATAERMAQSMLNA
What are the official names of this protein?
Acetaldehyde dehydrogenase 2, Acetaldehyde dehydrogenase [acetylating] 2.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: AROE_RHOPT
Sequence: MAATKRAACLIGWPAAHSRSPLIHHYWLRRLGIEGGYSIEAVPPEGFAEFVLHLKTHGYVGANVTIPHKERALQLTEPDERARAVGAANTLYYDGDLLRSTNTDIEGFIGNLDASAPGWDRSPHAVVLGAGGSSRAVVFGLLERGVQRIALANRSIERAQALRDLFGERVVPIAWSDIPAALPGAGLLVNTTSLGMKGQPPLQIDLSALPADAVVSDLVYVPLETDLLAAAKARGLRTADGLGMLLHQAVRGFDLWFGARPHVTAELRALVEADLAPK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.