PharMolix/UniProtQA huggingface dataset:
Protein: EF109_ARATH
Sequence: MHYPNNRTEFVGAPAPTRYQKEQLSPEQELSVIVSALQHVISGENETAPCQGFSSDSTVISAGMPRLDSDTCQVCRIEGCLGCNYFFAPNQRIEKNHQQEEEITSSSNRRRESSPVAKKAEGGGKIRKRKNKKNGYRGVRQRPWGKFAAEIRDPKRATRVWLGTFETAEDAARAYDRAAIGFRGPRAKLNFPFVDYTSSVSSPVAADDIGAKASASASVSATDSVEAEQWNGGGGDCNMEEWMNMMMMMDFGNGDSSDSGNTIADMFQ
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF109.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENTP5_MOUSE
Sequence: MATSWGAVFMLIIACVGSTVFYREQQTWFEGVFLSSMCPINVSAGTFYGIMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEVAKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSPFLVPDGSVSIMDGSYEGILAWVTVNFLTGQLHGRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEMGFEPCYAEVLRVVQGKLHQPEEVRGSAFYAFSYYYDRAADTHLIDYEKGGVLKVEDFERKAREVCDNLGSFSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLLQSLGITS
What is the function of this protein?
Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP (PubMed:10369669, PubMed:21074248).  In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases.  UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose (PubMed:21074248).  Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose (PubMed:21074248).  Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER (PubMed:21074248).
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 5, NTPDase 5, CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, GDPase ENTPD5, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, UDPase ENTPD5.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Secreted.
Protein: ATPI_PAUCH
Sequence: MVPLSFPFHVAELEVGQHLYWQIGNLNLHGQVFISSWVVISALLVLVITGTRKMERDPQGVQNLLEFLWDYLRDLAREQIGEKAYRDWLPFIGTLFLFIFGCNWGGALVPWKLIELPNGELGAPTADINTTVAMALLVSLSYFYAGLSRKGLRYFEYYVEPTPIMLPFKIIEDFTKPLSLSFRLFGNILADELVVGVLAFLVPILVPLPAMFLGLFTSAIQALIFATLAANYIGEAVHEEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, organellar chromatophore, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore thylakoid membrane; Multi-pass membrane protein.
Protein: GLMM_ECO55
Sequence: MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEVALGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MOCS3_AEDAE
Sequence: MEVDGETQIEELECDIRTLRKQLKAKVQQLKTLKKHFQKNCINKLNNNEIARYSRQIILSEIGVQGQLKLKRSSVLVVGAGGLGCPSALYLAGAGIGRIGILDYDEVELTNLHRQLLHTECSVGLTKVESVRSYLEELNSQIEIVTHHIQLTSDNALQTLESYDIVVDATDNVATRYLLNDACVLLKKPLVSGSALQLEGQLTVYNFNGGPCYRCLFPNPPPPETVTNCGDGGVLGAITGVIGALQALETIKIILGNSGVLSGRLLLFDGHQSTFRNLKLRPKKADCAVCSDNPSLTKLIDYEQFCSMKATDKDSHLNLLAPHERITVQEYKSLAESNVPHLLVDVRGANQFEICQLPASINVPIDDILKNRRTAEVTQLAATGGPVFVVCRRGNDSQLAVRHLSQLFQEQGLAPPRDIVGGLHAWTHNIDPEFPIY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A.  Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3, Molybdenum cofactor synthesis protein 3.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_PSEU2
Sequence: MSTPMDIKNALNRVVNQLDLTTEEMSDVMREIMTGQCTEAQIGAFLMGMRMKSETIDEIVGAVSVMRELAGKVELKTLDGVVDIVGTGGDGANIFNVSTASAFVIAAAGCTVAKHGNRAVSGKSGSADLLEAAGVYLNLTPVQVARCIDSVGIGFMFAQSHHTAMKHTAGPRRELGLRTLFNMLGPLTNPAGVRHQIVGVFNQALCRPLAEVLLRLGSKHVLVVHSQDGLDEFSLAAPTFVAELKNGEVTEYWVQPEDLGIKSQSLYGLAVESPAASLELIRDALGRRKTENGQKAAEMIVLNAGAALYAADHATSLKEGVALAHDALHTGLAREKLEELGAFTAVFKQENEA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: NM111_YEAST
Sequence: MTISLSNIKKRDHSKISDGTSGESSLVKRKQLESATGDQEEEYTDHEIIIEPLHFANNNNTVLTDSENYLRWQNTISNVVKSVVSIHFSQVAPFDCDSALVSEATGFVVDAKLGIILTNRHVVGPGPFVGYVVFDNHEECDVIPIYRDPVHDFGFLKFDPKNIKYSKIKALTLKPSLAKVGSEIRVVGNDAGEKLSILAGFISRIDRNAPEYGELTYNDFNTEYIQAAASASGGSSGSPVVNIDGYAVALQAGGSTEASTDFFLPLDRILRALICIQTNKPITRGTIQVQWLLKPYDECRRLGLTSERESEARAKFPENIGLLVAETVLREGPGYDKIKEGDTLISINGETISSFMQVDKIQDENVGKEIQLVIQRGGVECTVTCTVGDLHAITPHRYVEVCGATFHELSYQMARFYALPVRGVFLSSASGSFNFDSKERVGWIVDSIDNKETPDLDTFIEIMKTIPDRKRVTVRYHHLTDQHSPLVTSIYIDRHWCNEFRVYTRNDTTGIWDYKNVADPLPADALKPRSAKIIPIPVNNEKVAKLSSSLCTVATMAAVPLDSLSADILKTSGLIIDAEKGYVLVSRRVVPHDCLDTFVTIADSLVVPATVEFLHPTHNFAIVKYDPELVKAPLITPKLSTTRMKRGDKLQFIGFTQNDRIVTSETTVTDISSVSIPSNLIPRYRATNLEAISIDCNVSTRCNSGILTDNDGTVRGLWLPFLGERLENKEKVYLMGLDIMDCREVIDILKNGGKPRVSIVDAGFGSISVLQARIRGVPEEWIMRMEHESNNRLQFITVSRVSYTEDKIHLETGDVILSVNGKLVTEMNDLNGVVSSADGILPSAMLDFKVVRDGNIVDLKIKTVEVQETDRFVIFAGSILQKPHHAVLQAMVDVPKGVYCTFRGESSPALQYGISATNFITHVNEIETPDLDTFLKVVKTIPDNSYCKMRLMTFDNVPFAISLKTNYHYFPTAELKRDNITHKWIEKEFTGNSQSEK
What is the function of this protein?
Nuclear serine protease which mediates apoptosis through proteolysis of the apoptotic inhibitor BIR1.
What are the official names of this protein?
Pro-apoptotic serine protease NMA111, 111 kDa nuclear mediator of apoptosis.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIF6B_ARATH
Sequence: MERDFLGLGSKNSPITVKEETSESSRDSAPNRGMNWSFSNKVSASSSQFLSFRPTQEDRHRKSGNYHLPHSGSFMPSSVADVYDSTRKAPYSSVQGVRMFPNSNQHEETNAVSMSMPGFQSHHYAPGGRSFMNNNNNSQPLVGVPIMAPPISILPPPGSIVGTTDIRSSSKPIGSPAQLTIFYAGSVCVYDDISPEKAKAIMLLAGNGSSMPQVFSPPQTHQQVVHHTRASVDSSAMPPSFMPTISYLSPEAGSSTNGLGATKATRGLTSTYHNNQANGSNINCPVPVSCSTNVMAPTVALPLARKASLARFLEKRKERVTSVSPYCLDKKSSTDCRRSMSECISSSLSSAT
What is the function of this protein?
Repressor of jasmonate responses.  Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY6B/JAZ3 interaction.  Acts as a negative regulator of MYC2 function.  Feed-back regulated by MYC2.
What are the official names of this protein?
Protein TIFY 6B, Jasmonate ZIM domain-containing protein 3, Protein JASMONATE INSENSITIVE 3.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PG114_VARV
Sequence: MSINIDIKKITDLLNSSILFPDDVQELLREKYIVLERKSNGTPTVAHIYKTMARFDNKSIYRIAKFLFMNRPDVIKLLFLEDVEPLLPDKSINISINNTEYPQLEGPIGTKIALLELFNAFKTGISEPIPYYYLPLRKDINNIVTK
What is the function of this protein?
Late protein which is part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.
What are the official names of this protein?
Core protein D2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG114 family.
Protein: SYV_RICPU
Sequence: MKEFPKNYNFTENEKKWQQIWQEKQIYAYNPNVAKEETYVIDTPPPTVSGQLHIGHVYSYTQTDFIVRFQRMMGKNIFYPMGFDDNGLPTERLVEKQKQIKAYNMDRSEFIKICEEVVESEEEKFRSLFNQIALSVDWSLEYQTISPLSRKISQMSFLDLVQKEEIYLTNQPILWDPVDGTALAQADIEDKEKTSFMNYITFKTEQGDPLTIATTRPELLPACVAVFYHPDDGRYKHLAGKSAITPLFNEQVPLLADPLVRQDKGTGLVMCCTFGDQTDITWWKTHNLPLKTIITKKGTIDFQHETSIDGLKIKEARTKIIDILKEQELLIKQEDITHTVKCAERSGAPLEILTVPQWFVKTISHKEELLKRANELNWHPKNMKIRLENWINAISWDWCISRQRYFGVPFPVWYSKRVGEEGKILYADVTQLPIDPLKDLPMGYSKEEVEPDYDVMDTWATSSVSPQLSTHGISDDFAVNKDRHDKLFPMDLRPQAHEIIRTWAFYTILKAHLHQNTLPWKNIMISGWCLAEDRSKMSKSKGNVLVPEKLLEQYGSDVIRYWSANSKLGADTAYSEDVMKNGKRLVNKLWNAAKFVFIHFDKLKGEDKKASLLDIKEKITNEFDKWMVNKLVELVKLATNELQNYEYAHAMHLTEKFFWVVFCDNYLEISKTRSYDEEHKNPQGQYSSILTLYHVMQTLLKLFAPFMPHITEELYQILYSKNSIHVKGSWVNYSDLNYEINAKGAEGLLEILDIVRKFKAEKNLSIKAPIKLLEVSGIVLSAELAEDLKNVTSAEEIQFEMKDDKIKVNIIL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NM111_ASPFU
Sequence: MDLNGETSTKRKRSSVAAPAERPAKHLKPGNSTLTPGDATPANGTVYNVEDEEDTGRVMPIGPAQADSPEWQATIEKVVKSVVSIHFCQTCSFDTDLSMSSQATGFVVDAERGYILTNRHVVCAGPFWGYCIFDNHEECDVHPVYRDPVHDFGILKFNPKAIRYMELTELKLRPEAARVGCEIRVVGNDAGEKLSILSGVISRLDRNAPEYGDGYCDFNTNYIQAAAAASGGSSGSPVVNIDGHAIALQAGGRADGAATDYFLPLDRPLRALECIRRGEPVTRGTIQTQWILKPFDECRRLGLTPEWEAAVRKASPHETSMLVAEIILPEGPADGKLEEGDVLLQVNGELLTQFIRLDDILDSSVGKTVRLLVQRGGQNVEVECEVGDLHAITPDRFVTVAGGTFHNLSYQQARLYAIAARGVYVCEAAGSFKLENTLSGWIIDAVDKRPTRNLDEFIEVMKTIPDRARVVISYRHIRDLHTRGTSIVYIDRHWHPKMRMAIRNDETGLWDFSDLADPVPAETPVPRKADFIQLDGVSQPAVADIVRSFVRVSCTMPLKLDGYPQAKKTGFGLVIDAGKGLVVVSRAIVPYDLCDINITVADSIIVVAKVIFMHPLQNYTIIQYDPSLVQAPVQSAELSTEYIKQGQETIFVGFNQNFRIVVAKTAVTDITTVSIPANASAPRYRAINLDAITVDTGLSGQCTNGVLIGEDGVVQALWLNYLGERTPNSHKDVEYHLGFATPALLPVTSKIQQGIIPKLRILNMESYVVQMSQARIMGVSEEWIQKVAQANPSRHQLFMVRKVDCPPPQFTSNADSLQEGDIILTLDGQLITRVSELDKMYEKEVLDALIVRNGQEIHLKLPTVPTEDLETDRAVVFCGAVLQKPHHAVRQQISKLHSEVYVSARSRGSPAYQYGLAPTNFITAVNGVSTPNLDSFVREVSMIPDNTYFRLRAVTFDNVPWVVTMKKNDHYFPMSEYVKDPSQPLGWRTVSHERDRHKDGITPDAANLNPDAMDEVYEEVSDVEPEVD
What is the function of this protein?
Nuclear serine protease which mediates apoptosis.
What are the official names of this protein?
Pro-apoptotic serine protease nma111.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_AMOA5
Sequence: MAKEIVGYLKLQVKGGEAKPAPPVGPALGSKGLNIMEFCKQFNARTQDKQGQILPVLITIYQDKTFDFVIKTPPAAASIMQKAGISKGSSESNRNKVGVITWSAIKEIAASKMEDLNTINLESATKMIAGTARSMGVTIKE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: OTC_BRADU
Sequence: MSKSPKHFLDINELPLSELKSMLDASSAMKAKQKAHQPVRPLEGKTLAMIFERPSTRTRVSFDVAMRQLGGEPIMLTGAEMQLGRGETIADTARVLSRYVDAIMIRILNHDALLELAANATVPVINGLTRRSHPCQVMADLLTYQEHRGPIEGRTVAWTGDDNNVLASWAHAAERFKFQLNVATPPELAPKKAMRDWIKASGAPIMLGTDPEAAVRGADCVVTDTWVSMGDKEGEHRHNVLKPYQVNAKLMSLAKPDALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKGILAWCFDAVK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_ALKCK
Sequence: MEGFHATTIFAIAHNGGFAMAGDGQVTFGNAVVMKHTARKVRRLYHNNVLAGFAGSVADAFTLFEKFEAKLEEYNGNLQRASVELAKEWRSDRVLRKLEAMLIVMDKQALLLISGTGEVIQPDDGILAIGSGGNYALSAGRALKRHAPGLSAREIAVAALETAGEICVYTNDQIVVEELTE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH3_METM7
Sequence: MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHRGLAFYTRFDNIIAITNGIDLETHKRIQNSVKNRYPFTVSMAVASAETAYEAQKLATETIQEYGSAQDDVRKEVLDVANEFVSNGYVQLAHVDINDITGKLTDLETAYDTYLSVQMTKLKLMEELKKYDSMGFFIGGDNFMCPCNGMSEKDFLCMFEDIRDSCGIDLKAGIGIGKTAEDASNLADIGLEVIREGKTDFQVYTLKQSIEERKDITYNYMCPI
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: MURR_ECO24
Sequence: MLYLTKISNAGSEFTENEQKIADFLQANVSELQSVSSRQMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQRSSELTQRLK
What is the function of this protein?
Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc).  Binds to two adjacent inverted repeats within the operator region.  MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator.
What are the official names of this protein?
HTH-type transcriptional regulator MurR, MurPQ operon repressor.
Protein: RTP1_MOUSE
Sequence: MRIFRPWRLRCPALHLPSFPTFSIKCSLPPLPTDEDMCKSVTTGEWKKVFYEKMEEVKPADSWDFIIDPNLKHNVLAPGWKQYLELHASGRFHCSWCWHTWQSPHVVILFHMYLDKAQRAGSVRMRVFKQLCYECGTARLDESSMLEENIESLVDNLITSLREQCYGERGGHYRIHVASRQDNRRHRGEFCEACQEGIVHWKPSEKLLEEEATTYTFSRAPSPTKPQAETGSGCNFCSIPWCLFWATVLMLIIYLQFSFRTSV
What is the function of this protein?
Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs.
What are the official names of this protein?
Receptor-transporting protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMEM7 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Note=Effective cell surface expression depends upon interaction with olfactory receptors.
Protein: LEU3_SALCH
Sequence: MSKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDANDAATAIEQAINRALEEGVRTGDLARGAAAVSTDEMGDIIARYVAEGV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRB3_PIG
Sequence: MAPWPQGNSSLPPRPDVSTLAPNNANTSGLPGVPWAVALAGALLAPAVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGTTLALTGHWPLGATCCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRARAAVVLVWVVSAAVSFAPIMSKWWRVGADAEAQRCHSNPSCCTFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVATSQLRLLRWELSRFPPEESPPAPSRSQSPAPGRPWPSPAGVPSHGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFVVNVVRALGGPSLVPVPAFLALNWLGYANSAFNPLIYCHSPDFRSAFRRLLCRCGPEEHLAAASPPRAPSGAPETLTHPAESRQSPPLNEASWGLFRP
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  Beta-3 is involved in the regulation of lipolysis and thermogenesis.
What are the official names of this protein?
Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AZOR_LEGPH
Sequence: MKLLAIDSSILTNTSVSRQLTRSFVSRWQKIYPETEVVYRDLHAQPINHLSQKILAANSVPSTQISAEIREEMNLSMQLISELLSASVLVIGAPMYNFSIPSQLKSWIDRIVIAGKTFKYVDGKVQGLATGKRAYILSSRGGFYNAEPALNLDHQERYLTSILNFIGISDITFIRAEGVNVGEEIRTQSLHQAEAKIQQLLQFQMA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: Y2196_STAAC
Sequence: MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDSRILEALVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMRKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
What are the official names of this protein?
Uncharacterized hydrolase SACOL2196.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: GCSP_XYLFA
Sequence: MFSVSHFCSGSLMMSHTLSSLRDLEYQGAFVERHIGPNDVEIAQMLRVVGYDSLESLTDAIVPEKIRSTVALDLPKGITEEEALAKIRVIANKNRVFRSFIGQGYYGTHTPKVILRNVLENPAWYTAYTPYQAEISQGRMEALINFQTMCADLTGMEIANASLLDEATAAAEAMSLAKRSAKSRSDLFFVHDAVHPQTLELLRTRAEPLGIVLRVGTPEEALQADVFGILLQYPDTFGRIGDHRVLADAVHARGGLVAVASDLLALTLITPPGEWGADIVVGNSQRFGVPFGFGGPHAGFMACRDIYKRSIPGRLIGVSVDAAGHPAYRLALQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPQGLLRIAWRTHRMAAILAAALRGAGLTVGEYFFDTLHIVGIDAVAIHCAAAAAGMNLRMIDNAQLGISLDETVTRSDVVALGQVFGVQVDVEALDAITADALPAGLLRSSAFLTHPVFNTHHSEHELLRYLRMLADKDLAMDRTMIPLGSCTMKLNATAEMIPVTWQEFACIHPLAPAVQWSGYRQLIDELEAMLAECTGYDAISLQPNSGAQGEYAGLLAIRAYHRSRGEERRNVCLIPESAHGTNPASAQLCGMQVVIIKCDRSGNVDVDDLRMKAEKYSDSLAALMVTYPSTHGVFEEAITEICEIVHAHGGQVYTDGANMNALVGVAKPGRWGSDVSHLNLHKTFCIPHGGGGPGVGPCAVKAHLAPFLPKTLPLPGDAAGLPVQGTQEAKVGMVSAANFGSASILPVSWMYITMMGAAGLRKATQVALLNANYIAKRLAPHYKTLYTGRHGLVAHECILDVRPLEKVSGVSAEDIAKRLIDFGFHAPTLSFPVAGTLMVEPTESESQQELDRFVDAMIQIRGEIAAIEKGHLDPEDNPLKQAPHTAVQVMASQWGHAYSRELAAFPLGVLHHAKYWPPVARVDNVYGDKHVMCACIPVEAYKEKEDSEIQHLIEEDASRC
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: SP1_ARATH
Sequence: MIPWGGVTCCLSAAALYLLGRSSGRDAEVLETVTRVNQLKELAQLLELDSKILPFIVAVSGRVGSETPIKCEHSGIRGVIVEETAEQHFLKHNETGSWVQDSALMLSMSKEVPWFLDDGTSRVHVMGARGATGFALTVGSEVFEESGRSLVRGTLDYLQGLKMLGVKRIERVLPTGIPLTIVGEAVKDDIGEFRIQKPDRGPFYVSSKSLDQLISNLGKWSRLYKYASMGFTVLGVFLITKHVIDSVLERRRRRQLQKRVLDAAAKRAELESEGSNGTRESISDSTKKEDAVPDLCVICLEQEYNAVFVPCGHMCCCTACSSHLTSCPLCRRRIDLAVKTYRH
What is the function of this protein?
E3 ubiquitin-protein ligase involved in the regulation of protein import in the chloroplast.  Associates with TOC complexes and mediates ubiquitination of TOC components, promoting their degradation via the ubiquitin-proteasome system (UPS).  Plays a role in the reorganization of the TOC machinery.  Involved in a mechanism that regulates plastid biogenesis via UPS (PubMed:23118188).  Promotes stress tolerance by depleting the chloroplast protein import apparatus, which limits photosystem assembly and the potential for reactive oxygen species (ROS) formation (PubMed:26387714).  May act as negative regulator of programmed cell death (PCD) during biotic stress (PubMed:20972793).
What are the official names of this protein?
E3 ubiquitin-protein ligase SP1, DIAP1-like protein 1, Protein SUPPRESSOR OF PPI1 LOCUS 1, RING-type E3 ubiquitin transferase SP1.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Multi-pass membrane protein.
Protein: TRMY_METJA
Sequence: MREFIFKANKTITSSDINLKDLPGSCGRLDLLCRCVSDAFFLSHDIRRDVVFYAVLYGQPNPPVCIKFVGSELKKVSPDERNIAIFIKKALKKFEELDEEQRKDWNQSTPGIYVRRLGFRNLVLEKLEEGKNIYYLHMNGEDVENVDIENPVFIIGDHIGIGEEDERFLDEIKAKRISLSPLELHANHCITIIHNVLDKKRICEI
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3NO26_NAJNA
Sequence: LTCLICPEKYCNKVHTCLNGEKICFKRYSERKLLGKRYIRGCADTCPVRKPREIVQCCSTDKCNH
What is the function of this protein?
Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Weak neurotoxin 6.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.