PharMolix/UniProtQA huggingface dataset:
Protein: YIHO_ECOLI
Sequence: MSDHNPLTLKLNLREKIAYGMGDVGSNLMLCIGTLYLLKFYTDELGMPAYYGGIIFLVAKFFTAFTDMLTGFLLDSRKNIGPKGKFRPFILYAAVPAALIATLQFIATTFCLPVKTTIATALFMMFGLSYSLMNCSYGAMIPAITKNPNERAQLAAYRQGGATIGLLICTVAFIPLQSLFSDSTVGYACAALMFSIGGFIFMMLCYRGVKEHYVDTTPTGHKASILKSFCAIFRNPPLLVLCIANLCTLAAFNIKLAIQVYYTQYVLNDINLLSWMGFFSMGCILIGVLLVPLTVKCFGKKQVYLAGMVLWAVGDILNYFWGSNSFTFVMFSCVAFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFFRKISAALAGFLPGIMLTQIGYVPNIAQSDATLQGLRQLIFIWPCALAIIAALTMGFFYTLNEKRFALIIEEINQRKNKEMATEEKTASVTL
What is the function of this protein?
Could be involved in sulfoquinovose import.
What are the official names of this protein?
Putative sulfoquinovose importer.
What is the protein family that this protein belongs to?
Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GGT1_ARATH
Sequence: MALKALDYDTLNENVKKCQYAVRGELYLRASELQKEGKKIIFTNVGNPHALGQKPLTFPRQVVALCQAPFLLDDPNVGMLFPADAIARAKHYLSLTSGGLGAYSDSRGLPGVRKEVAEFIQRRDGYPSDPELIFLTDGASKGVMQILNCVIRGNGDGILVPVPQYPLYSATISLLGGTLVPYYLDESENWGLDVANLRQSVAQARSQGITVRAMVIINPGNPTGQCLSEANIREILKFCYNEKLVLLGDEVYQQNIYQDERPFISSKKVLMEMGSPFSKEVQLVSFHTVSKGYWGECGQRGGYFEMTNLPPRVVEEIYKVASIALSPNVSAQIFMGLMVNPPKPGDISYDQFARESKGILESLRRRARLMTDGFNSCKNVVCNFTEGAMYSFPQIRLPTGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSGFGQKEGVFHLRTTILPAEDEMPEIMDSFKKFNDEFMTQYDNNFGYSKM
What is the function of this protein?
Catalyzes the glutamate:glyoxylate (GGT or GGAT), alanine:glyoxylate (AGT), alanine:2-oxoglutarate (AKT) and glutamate:pyruvate (GPT) aminotransferase reactions in peroxisomes.  Required for abscisic acid (ABA)- and stress-mediated responses in an H(2)O(2)-dependent manner.  Functions as a photorespiratory aminotransferase that modulates amino acid content during photorespiration (GGAT activity); promotes serine, glycine and citrulline metabolism in response to light.
What are the official names of this protein?
Glutamate--glyoxylate aminotransferase 1, AtGGT2, Alanine aminotransferase GGT1, Alanine--glyoxylate aminotransferase GGT1, Alanine-2-oxoglutarate aminotransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
What are the subcellular locations of this protein?
Peroxisome.
Protein: NEC1_EBVA8
Sequence: MAPVTPDAVNARQQRPADPALRRLMHPHHRNYTASKASAHSVKSVSRCGKSRSELGRMERVGSVARSICSRHTRHGVDRSHFSLRDFFRGISANFELGKDFLREMNTPIHVSEAVFLPLSLCTLSPGRCLRLSPFGHSLTLGSHCEICINRSQVHVPQEFSSTQLSFFNNVHKIIPNKTFYVSLLSSSPSAVKAGLSQPSLLYAYLVTGHFCGTICPIFSTNGKGRLIMHLLLQGTSLHIPETCLKLLCENIGPTYELAVDLVGDAFCIKVSPRDTVYEKAVNVDEDAIYEAIKDLECGDELRLQIINYTQLILENKQ
What is the function of this protein?
Plays an essential role in virion nuclear egress, the first step of virion release from infected cell.  Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2.  Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space.  There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network.
What are the official names of this protein?
Nuclear egress protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae NEC1 protein family.
What are the subcellular locations of this protein?
Host nucleus inner membrane. Note=Remains attached to the nucleus inner membrane through interaction with NEC2.
Protein: BRAT1_DANRE
Sequence: MDGDCSSLLPAVCLVLADPKQTPPDDTSLEKLLDWFKDLHSQSNGQVLLEHQPCLLEFISSVCASKATDPAILSFTLKLTGLLAASKQDFHLLEEGGHLVCVFEREAWSVCDLWEDASVRSGWIQGLLNMLKHQQALDFICRQGLIKVILQLQNDRSLFVACLANQLLVQILKLLTPSDVTSGSDAVVSSKSSSSLDWVSVSSEITNAVVEALSSENHPQVLQGVQLLSLVLSQCEEPIRSSLWKDVLPPLEVLINRGSEPLTQPLMTVLRAAVMTPLLGQSEYKVEEFLEVMLGTGNRKEGILCATLIVKLEKCPKVLKRKAMDIILLPLQCVSTQSQDEKEVDLVLKEPLSQKALCISLLVQSLSSLAELAHKEYFEGVCIPSVTSRVVQLLRVCSGHCTSSLLHVSACTHLIGSCKIQRCGLDTLGALSVYEDNLDLRKDIFGVLLDYLKSPDSHATVLKKTFQAVLRWIGVCASFPDLLQFISNDLFPVLEKRMCDVRWEVRDSTLEFITQLTVALSDNSGFVEVLYTSGLVSILLSLLSDTEGYVRASAVTAVGEAVTSSVQQMALVSKINLLEEALAQMMIILSQDTEGFPRRAVVKTFTSWLKGSNPITALDSSLSSVLSLGGNDFDWEVKMHTLELAEALMEKMLTCCPYAVQSFSSSERTRLTQSLSKLKDLGLFDVLLNGLFDCDRPVCEKSCQLLLKLKRLNAEKADFDHDALVLKACGNRWGDEVQSRFLNKQQVKASEHVLIGGGEGTEKDLHCIKEIPLSVILQILDLDDMQRMLKLSSDHVVNSPRSLMEDILSAAQQSEENIVDCY
What is the function of this protein?
Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress.
What are the official names of this protein?
BRCA1-associated ATM activator 1, BRCA1-associated protein required for ATM activation protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Present at double strand breaks (DSBs) following ionizing radiation treatment.
Protein: RF1_XANP2
Sequence: MTALPTAKLDQLVARHAEIEAALSRGAEGEEYVRLGREFSDLSPVVEQVRALKDAERDLEGANELLAESAADPEMREMAEAEVERLQDRIEALATAVRLALLPKDAMDERGIILEVRAGTGGDEAALFAGDLYRMYTRYAAEKGWSVEILSESEGTMGGYKEIVAALHGRGAYARLKFESGVHRVQRVPATETSGRIHTSAATVAVLPEAEDVDVDINEADLRIDVYRAQGAGGQHVNKTESAVRITHLPTNTVVAVQDERSQHRNKARAMALLRARLLDDERQKKEAGRAAERKGQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDEVIAGTALDEIIDPLLTEHQAALLAAAEDA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CG21_CANAX
Sequence: MPQVTKTNNENEFRLTRSKVQHQESISTIKNTTISNSQHKQQTQQQISSPPQVSVTSSEGVSHVNTRQYLGDVSNQYITNAKPTNKRKPLGGDNAPLQKQQHRPSRPIPIASDNNNNGSTSSSSNSSNNNNNDANRLASLAVPSRLPQKRQATESSTNLVEKLRVPQPEVGERSQSYHKKSRLIDYEWQDLDEEDNDDQLMVSEYVNEIFSYYYELETRMLPDPQYLFKQTLLKPRMRSILVDWLVEMHLKFKLLPESLFLAVNVMDRFMSVEVVQIDKLQLLATAALFTAAKNEEVFSPSVKNYAYFTDGSYTPEEVVQAEKYMLTILNFDLNYPNPMNFLRRISKADDYDVQSRTLGKYLLEITIVDYKFIGMRPSLCCASAMYLARLILGKLPVWNGNLIHYSGGYRISDMRECIELMFQYLIAPIEHDEFFKKYAMRKFMRASTLCRNWAKKFQASGRDLFDERLSTHRLTLEDDDEEEEIVVAEAEE
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.  Interacts with the CDC2 protein kinase to form MPF.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis (By similarity).
What are the official names of this protein?
G2/mitotic-specific cyclin CYB1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: HIS5_CARHZ
Sequence: MTVVVDYEMGNLLSVTKALEELGYKPSVTSDPRKILEEDLVVLPGVGAFRDAVRNLKEKGLFLALKERASLNRPILGICLGMQLFFTKSYEDGEYEGLDLIPGEVVRFQKAPKIPHMGWNNLVPVDTTHELFKNLPDYYVYFVHSYYAQTDSRYVLAYTEYGEKFPAAVRRGSIIGFQFHPEKSGPVGRQILKNLREML
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGI3_BACTU
Sequence: MMAIFISIVLVVSFVLFNRVQAKKSIYNYIARQGIQESQLKYIDFHKDFKMGGYWLAVYVEGENPDIYYEYSYQDKKVNFQAYFNSEKAIKKKMWGGSGLTEIEMKKLKYPPLQ
What is the function of this protein?
Possibly involved in pGI2 replication mechanism.
What are the official names of this protein?
Uncharacterized 13.4 kDa protein, ORF 3.
Protein: YQGF_POLSJ
Sequence: MSLAAVPHLTAGLQTFLAFDFGLQRTGVATGNVLTRTATPQATIAATGDARLKAIELRIREWQPDALVVGIPFHPDGASHENTRRAQKFSRQLRARFGLKVFEVDERYSTTEALAGGAADADAASACIILEQFLRSLP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_STAS1
Sequence: MGHIFEGVGVALATPFTHNEVDFDALRRHVKYLLDNNAKSIVVNGTTAENPTLTDEEKDQILEVVVNVVDGRVPVIAGTGTNNTQKSIQASVRAREIGADAIMLITPYYNKTNQRGLIAHFTTIADAVKLPVVLYNVPSRTNMTIDAETVETLSENEYIVALKDATNDFDYLEDLKQRLNLDEFALYSGNDDNIVDYFNQGGHGVISVVANVIPNAFQSLYDAKQNDENIQSQFQPIQTLLDALAVDVNPIPVKALTAVEGFGNYEVRLPLVTLEDSDRQKLEQAYEQFKVGGNS
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_CLOBK
Sequence: MFNLKNRNFLTLMDFTPKEINYFLDLARDLKRAKYTGTEVQRMKGKNIALIFEKASTRTRCAFEVGAKDQGAHVTYLGPTGSHIGKKESAADTARVLGRMYDGIEYRGFGQEIVETLAEYAGVPVWNGLTDEDHPTQILADFLTIREHFNKPLNEIKFAYVGDGANNMANALMIGAVKMGMDFRIVSPKEIPTDATLVAKCKEIAAETGAKVTITDNIEEGVKGCDVLYTDVWVSMGEPDSVWESKIKLLTPYRVDMNMIKMTGNPDAKFMHCLPAFHDEETAVGKEIKEKYGLSEMEVSHELFESKYSIVFDEAENRMHTIKAVMVATLGDQ
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGM_ECOLI
Sequence: MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVLAANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTKVVEDRANALLADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPQWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQAAATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase, PGM, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2121_ACIBT
Sequence: MLAQFDVNLVVLLVLLICGLLSQNAAVTIAAGILIVIKITPLNQFFPYIQAHGLNLGILILTIGVLTPIASGKLSGESILKSFISFKSLVAIAIGLLVAWLGGRGVKLMSSQPDVVAGLLIGTVAGVALLRGVPVGPLIAAGLLSLFIGK
What are the official names of this protein?
UPF0756 membrane protein A1S_2121.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FUR_HELPY
Sequence: MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTSISSVYRILNFLEKENFICVLETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIENRQNEVVKKYQAKLISHDMKMFVWCKECQESEC
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_SALG2
Sequence: MLWFKNLMVYRLSRDITLRAEEMEKQLASMTFTPCGSQDMAKMGWVPPMGSHSDALTHTANGQIIICARKEEKILPSPVIKQALEAKIQKLEADQGRKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLALENPIELTLTEWVRSGTVAQGFQLLDEAELKAMLEDGGVIRAKKQDLVSDEIAVHIEAGKVVTKLALDWQQRIQFVMCDDGSIKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQSLVEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: S6A13_RAT
Sequence: MDNRVSGTTSNGETKPVCPVMEKVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRKICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKTNNSLNVTSENATSPVIEFWERRVLKISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCVALCILNSSTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREILILIVSVVSFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQKSQPELTSPATPMTSLLRLTELESNC
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:1400419, PubMed:22896705).  Mediates transport of taurine and is the major taurine transporter in hepatocytes (PubMed:22896705).  Can also mediate transport of beta-alanine and hypotaurine (By similarity).
What are the official names of this protein?
Sodium- and chloride-dependent GABA transporter 2, GAT-2, Solute carrier family 6 member 13.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: RLME_BORDL
Sequence: MYNVFDEYSQKAKNEGYLARSVYKLIEIDKKFSLFSSGNILDIGASPGSFSQYAYANLKNGVLVAVDLNDVNLNFTSNFYFIKGNIYLDEVYQKIKIFSPYSLIVSDAAPSTTGNRLVDTSNSFNLNIRIFELACESLMRGGNLLIKVFQGGEEEQIFYKLKSCFRVVKKVRPKAVRKNSFEIYFLAKDFAKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BACCN
Sequence: MPRVKGGTVTRKRRKKMIKLAKGYYGSKHTLFKVANQQVMKSLLYAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKLAGIEVNRKMLADLAVHDEKAFAELATVAKNNLK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: IPYR_THEAC
Sequence: MESFYHSVPVGPKPPEEVYVIVEIPRGSRVKYEIAKDFPGMLVDRVLYSSVVYPVDYGLIPRTLYYDGDPMDVMVLISQPTFPGAIMKVRPIGMMKMVDQGETDNKILAVFDKDPNVSYIKDLKDVNAHLLDEIANFFSTYKILEKKETKVLGWEGKEAALKEIEVSIKMYEEKYGKKN
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTI_SALPC
Sequence: MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLYA_YERPS
Sequence: MESTLGSDLARLVRVWRALIDHRLKPLELTQTHWVTLYNINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHTCANDRRAKRIKLTEQSSPIIEQVDGVICSTRKEILGGISSDEIAVLSGLIDKLEKNIIQLQTK
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.  Required for expression of the virulence gene inv.
What are the official names of this protein?
Transcriptional regulator SlyA, Regulator of virulence protein A, Transcriptional regulator for cryptic hemolysin.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: GATA_MARMS
Sequence: MFEQSISTLAQKLRNKDISSVELTRLFLARIAKLDPQLNSFITVSEQHALEQAAAADVLLQSGKGTSLTGIPVAHKDLFCTEGTLTTCGSKMLHNFVPPYESTVTSRIQQAGAVMLGKTNMDEFAMGSSNENSFYGAVKNPWNLDMVPGGSSGGSAAAIAAGLAVAATGTDTGGSIRQPASFCGITGLKPTYGRVSRFGMIAYASSLDQGGPMAKSAEDCAHLMQAMAGFDEKDSTSADKPADDYLANLNSPLTGLKIGLPKEYFGEGLDSKVADVIMAAVKEFEKLGATVKEISLPNLQLSIPSYYVIAPSEASSNLSRFDGVRFGHRCDDPKDLLDMYTRSRAEGFGTEVQKRIMVGTYALSEGYYDAYYLKAQKIRRLIKEDFVKALEEVDVIMGPVAPTTAFGLGSKTSDPVAMYLEDIYTLSVNLAGIPAMSVPAGFADGMPVGLQVMGNYFAEAKLLNIAHQYQQHTDWHLQTPTMAKGA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: FTSK_VIBCH
Sequence: MFKENKNKVETIIKTSEEAPSSRLNGSQRLKESGLILAFLFSIFLAVALFSFNPADPSWSQTAWGTDIHNAGGLVGAWLADTLFFVFGSLAYPLPFITAFAAWVLLRKRDEGDEIDFTLWGTRLLGLTIVLLTSCGLADINFDDIWYFSSGGVIGDVLTSLALPTLNILGTTLVLLFLWGAGITLLTGISWLRIVEWIGERSIAAFVGLFNRLRGEKAERVKPALVKPELPVEELEPTFSASMDTEIDEPAPSLRRFNIHMPEERDVPDIHFEPQVEPKVELKPEPPRQREPAPHFSRVAAQNTQVEPVSSARTQQWDATIEELEQQARLVDDYAVEDDAVPSVLTSSTLSDVEDSILTTAISVDEEEESLSENFNHSFNIEVEDEEVEPSIANLHWSDDEDELEETPSVMVSPAIESDWEDEDEPDDRDVAAFQNIVSQAQANAAAQQNPFLVQKAVNLPKPTEPMPTLELLYHPEKRENFIDREALEEIARLVESKLADYKIQAQVVDIFPGPVITRFELDLAPGVKVSRISSLSMDLARSLSAMAVRVVEVIPGKPYVGLELPNMSRQTVYLSDVIASPQFKESKSPTTVVLGQDIAGDAVVADLSKMPHVLVAGTTGSGKSVGVNVMILSMLYKASPEDVRFIMIDPKMLELSVYEGIPHLLAEVVTDMKDASNALRWCVGEMERRYKLMSVLGVRNIKGFNDKLRMAAEAGHPIYDPLWKDGDSMESEPPLLEKLPYIVVVVDEFADLMMVVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRVAFTVSTKTDSRTILDQSGAESLLGMGDMLYLPAGSSHTIRVHGAFASDDDVHAVVNNWKARGKPNYISEIIQGDHGPEALLPGEQSESDEELDPLFDQVVEHVVETRRGSVSGVQRRFKIGYNRAARIVEQLEAQGIVSAPGHNGNRDVLAPAPIRD
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: CNGA1_BOVIN
Sequence: MKKVIINTWHSFVNIPNVVGPDVEKEITRMENGACSSFSGDDDDSASMFEESETENPHARDSFRSNTHGSGQPSQREQYLPGAIALFNVNNSSNKEQEPKEKKKKKKEKKSKPDDKNENKKDPEKKKKKEKDKDKKKKEEKGKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMIIARACFDELQSDYLEYWLAFDYLSDVVYLLDMFVRTRTGYLEQGLLVKEERKLIDKYKSTFQFKLDVLSVIPTDLLYIKFGWNYPEIRLNRLLRISRMFEFFQRTETRTNYPNIFRISNLVMYIIIIIHWNACVYFSISKAIGFGNDTWVYPDVNDPDFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYFFVVADFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEREVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKGMLEEKGKQILMKDGLLDINIANAGSDPKDLEEKVTRMESSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSAIEGSGTESGPTDSTQD
What is the function of this protein?
Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway.  When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.
What are the official names of this protein?
cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel 1, Cyclic nucleotide-gated channel alpha-1, CNG channel alpha-1, CNG-1, CNG1, Cyclic nucleotide-gated channel, photoreceptor, Rod photoreceptor cGMP-gated channel subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RMD3_BOVIN
Sequence: MSSLGTLGGARAGLGLLLGTAAGLGFLCALYSQRWKRTQRRGQSQSQSNSLDYTQTSEPGRQVRPLRAAPGEAGDAAVLSSLPRGQEVVLDRLEFVLTSLVALRREVEELRSSLQGLAGQIVGEVRSHMEENQKVARRRRFPFARERSDSTGSSSVYFTAASGATFTDAESEGGYTTANAESDYERDSERESDGDGEDEVSCETVKMGRKDSLDLEVEVALGLEPEAPEAGGSPGQEDVMPLLQQADELHQGSEQGKREGFQLLLNNKLVHGSRQDFLWRLARAYSDMCELTEEASEKRSYALSGKEEAEVALEKGNENAECHQWYAVLCGQLAEHEGIQRRIQSGFSFKEHVDKAIALKPENPMAHFLLGRWCYQVSHLSWLEKKTATALSESPLGATVQDALSSFLKAEELQPGFSKAGRIYICKCYKELGKNPEAKEWMKLALELPNVTKEDSAFQKDLEELEVILGE
What is the function of this protein?
Involved in cellular calcium homeostasis regulation (By similarity).  May participate in differentiation and apoptosis of keratinocytes.  Overexpression induces apoptosis (By similarity).
What are the official names of this protein?
Regulator of microtubule dynamics protein 3, RMD-3, Protein FAM82A2, Protein FAM82C.
What is the protein family that this protein belongs to?
Belongs to the RMDN family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.
Protein: HIS4_SHEPA
Sequence: MIIPAIDLIDGQVVRLYQGDYAQQTTFNLSPLDQLKSYQQQGASLLHIVDLTGAKEPDRRQTALISELVNNLDTPIQVGGGIRTEAQLSELLEIGVSRVVIGSLAVKEPELVKSWFTKYGSDAICLALDVNINEQGEKIVAVSGWQSGGGKSLESLVEEFKSVGLKHALVTDISRDGTLKGANTELYYEIATLYPEIQWQASGGIATLDDVNAVKQSGATGIIIGKALLINQFTVEEAIACWPNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.