PharMolix/UniProtQA huggingface dataset:
Protein: Y2451_ARATH
Sequence: METRNKFMLLACATFSIMSLVKSQNQQGFISLDCGLPSKESYIEPSSNLTFISDVNFIRGGKTGNIQNNSRTNFIFKPFKVLRYFPDGIRNCYSLSVKQGTKYLIRTLFYYGNYDGLNTSPRFDLFLGPNIWTSVDVLIADVGDGVVEEIVHVTRSNILDICLVKTGTSTPMISAIELRPLRYDTYTARTGSLKSMAHFYFTNSDEAIRYPEDVYDRVWMPYSQPEWTQINTTRNVSGFSDGYNPPQGVIQTASIPTNGSEPLTFTWNLESSDDETYAYLFFAEIQQLKVNETREFKILANGVDYIDYTPWKFEARTLSNPAPLKCEGGVCRVQLSKTPKSTLPPLMNAIEIFSVIQFPQSDTNTDEVIAIKKIQSTYQLSRISWQGDPCVPKQFSWMGVSCNVIDISTPPRIISLDLSLSGLTGVISPSIQNLTMLRELDLSNNNLTGEVPEFLATIKPLLVIHLRGNNLRGSVPQALQDREKNDGLKLFVDPNITRRGKHQPKSWLVAIVASISCVAVTIIVLVLIFIFRRRKSSTRKVIRPSLEMKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFLNNEQVAVKVLSQSSTQGYKEFKTEVELLLRVHHVNLVSLVGYCDEGIDLALIYEFMENGNLKEHLSGKRGGSVLNWSSRLKIAIESALGIEYLHIGCQPPMVHRDVKSTNILLGLRFEAKLADFGLSRSFLVGSQAHVSTNVAGTLGYLDPEYYLKNWLTEKSDVYSFGIVLLESITGQPVIEQSRDKSYIVEWAKSMLANGDIESIMDPNLHQDYDSSSSWKALELAMLCINPSSTQRPNMTRVAHELNECLEIYNLTKIRSQDQNSSKSLGHTVTFISDIPSAR
What are the official names of this protein?
Leucine-rich repeat receptor-like serine/threonine-protein kinase At2g14510.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GSA1_STAAT
Sequence: MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGNDIAGVIVEPVAGNMGVVPPIEGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILEDGLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_PSELT
Sequence: MAQQQKKRRKRKVKKCKLCEMKVEYVDYKDLRLLNEFLTDKAKIIPKRVTGNCAKHQRMIKIAIKRARHMALLPFIKL
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PSBA1_NOSS1
Sequence: MTTTLQQRSSANVWERFCTWITSTENRIYVGWFGVLMIPTLLAATVCFIIAFVAAPPVDIDGIREPVAGSLIYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLIGCACYLGRQWELSYRLGMRPWICVAYSAPLASATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTEIESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRQLHFFLAAWPVIGIWFTALGVSTMAFNLNGFNFNQSIIDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAGEVAPVALTAPAING
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 1, PSII D1 protein 1, 32 kDa thylakoid membrane protein 1, Photosystem II Q(B) protein 1.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CCD96_MOUSE
Sequence: MDSHYGDIEGKDRAEEGLARQSLEIKVSSEPLTPANPVEQEPEPKPEPEPTQGREPESETQPVSDSSKAKDSEGIDYAHVEVPESPGAAETAGEAVSREPESLPQTQPKTKPESKEPEDKDEDEDEDEDEDEDEDEDEDEDEDEGEERDRPEKPKGKGKREKRKESRFRPSLPLTTIVEEGAAPGPQAAKEKARESLKKRDSEEIEGTDRERHKSTEEQLHPGEAKEEEKQKGASTEEFEWTADMQKLQEQQLRGELVEQYHSLLVERNRYQRYNMYLQQKIHETLRKKGLEAAAEPGDKSAEPESPEKEQAYLRYLAMLEELKKQEADDLEWYRQEVRELKQQCQEKQTRVEKEWRRFQALKKQVVMQVMGSCRTRGGRQAALREVEQLQALEDKKEKEMSAVRLENVQLKQSLVHFETRMKAQEDLAEGLLLIDFEQLKIENQTFNEKVEERNEELLKLRTKVTSNVQIITHVKEKLSFIDTENSCKKAQLSEVDAQVALGRDLLTKTKQARDSLRIDNVKLSQKCGLLGKESLLRDLEEKVEKTEMLNRRLESLKRHHAGLALSCKGVKQKIREAKTFLPS
What are the official names of this protein?
Coiled-coil domain-containing protein 96.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: UCRI_SYNPW
Sequence: MTQMPAGDVPGMGRRQFMNLLTFGSVTGVALGALYPVVNYFIPPRAAGSGGGTSAKDELGNAVTASGWLSTHPAGDRSLVQGLKGDPTYLIVEGDDAIGSYGINAICTHLGCVVPWNSGANKFMCPCHGSQYDATGKVVRGPAPLSLALANVSVENDNVFVSQWTDTDFRTGEKPWWA
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: RL6_PSYIN
Sequence: MSRIAKAPITVPSGVEVVVNGQNVAVKGNKGELVCLLNDAVVIKLEEGVIRFAPAEGFKDGWAQAGTARANVNNMVLGVTEGFKKTLLLQGVGYRAQVAGTIVNLTLGFSHPVAYQLPEGITAVAKSQTEIILEGADKQVVGQAAAKIRAFRPPEPYKGKGVRYANEIVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DOPR4_CAEEL
Sequence: MLAYGSDPNAEDLYITMTPSVSTENDTTVWATEEPAAIVWRHPLLAIALFSICLLTVAGNCLVVIAVCTKKYLRNPTGYLIISLAIADLIVGVIVMPMNSLFEIANHTWLFGLMMCDVFHAMDILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVWVLSAILSFPGIIWWRTSSPHLYEDQSQCLFTDSKMYVSFSSLVSFYIPLFLILFAYGKVYIIATRHSKGMRMGIKTVSIKKRNGKKSNTETESILSSENEPTLRIHFGRGKQSSSSLRNSRFHARESTRLLLKQVSCKSLNDRGEHNNNNTVRQPLLRGTEGCHSDSISRSSQRNFRGRNVTIGSNCSSTLLQVDQPDRMSLSSNSQMVMTSPLSTRRKLNVREKSRQMMRYVHEQRAARTLSIVVGAFILCWTPFFVFTPLTAFCESCFSNKETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQILTCQRQQKVKTAFKTPLSLVFTQLISVTQMWEQPPNTSIE
What is the function of this protein?
Receptor for dopamine.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  In terms of antagonist responses, would be classed with the D1-like dopamine receptor group.
What are the official names of this protein?
Dopamine receptor 4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOB_THEFY
Sequence: MGLEEKLPSGVLLTTVEQIVGFVRKTSMWPATFGLACCAIEMMAAGGPRFDIARFGMERFSATPRQADLMIVAGRVSQKMAPVLRTIYDQMAEPKWVIAMGVCASSGGMFNNYAIVQGVDHIVPVDIYLPGCPPRPEMLLDAILKLHDKVQNTKLGVHREREIEELEQRRLRALPLIQQTEEATR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS14Z_CLOK5
Sequence: MARKALIEKWKKTPKYATKAYTRCRICGRPHAVLKKYGICRICFRELAYKGEIPGCKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: CH10_BACCZ
Sequence: MLKPLGDRVVIELVQAEEKTASGIVLPDTAKEKPQEGKVIAVGTGRVLENGERVALEVAAGDLIIFSKYAGTEVKYEGTDYLILRESDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_BAUCH
Sequence: MDFRVKSGRLEKQRSACIVAGVFESRQFSFIAEQLDKISKGYISALLRSGELEGQVGQVLLLYHVPYIMSKRVLLIGCGKKRELDERKYKKIIINTVNALNNTGSIEAMCFLTELQVQGKNTYWKIRQAVEIAHNLCYTFDKFKKTKKISYQLRRITFNITNRRELTSSKCALQHGIAIAAGIKAAKDLANMPPNICNSAYLASKAHELANSNKHINASVLGKQQMKELGMNAYLAVGQGSANESLMSIIEYQGHLDSKARPIVLVGKGLTFDSGGISIKPSNKMNEMKYDMCGAATVYGVMRVVLSLNLPLNIIGVLAGCENMVDSCSFRPGDVLTTLSGQTVEVLNTDAEGRLVLCDTLTYIERFNPEIVIDIATLTGACVIALGHHFTGMMSNHNPLSNELSSAAEQAGDYIWPLPLSNEFHEELDSHCADMTNVGGSAGGAITAGCFLSRFTSKYHWAHLDIAGTAWNTEKHQGATGRPVAMLSQFLINRSISDNK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1433_PEA
Sequence: MAAAHTPREENVYMAKLAEQAERYEEMVEFMEKVSANADSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEDHVAVIRDYRSKIESELSNICDGILKLLDTRLIPSASSGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTGYKSAQDIANAELPPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQDDGADEIKEAAPKADEQQ
What are the official names of this protein?
14-3-3-like protein.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: DAD1_SOLLC
Sequence: MAKSSATKDAQALFHSLRSAYAATPTNLKIIDLYVIFAISTALIQVVYMAIVGSFPFNSFLSGVLSCIGTAVLAVCLRIQVNKENKEFKDLPPERAFADFVLCNLVLHLVIMNFLG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, Defender against cell death 1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MNHC2_STAEQ
Sequence: MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGKYGPHMSEPLIQGHAQNFVDPLLQAIVLTAIVIGFGMTAFLLVLIYRTYRVTKEDEISALKGDEDDE
What are the official names of this protein?
Putative antiporter subunit mnhC2, Mrp complex subunit C2, Putative NADH-ubiquinone oxidoreductase subunit mnhC2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAK_PARD8
Sequence: MGKIIGIDLGTTNSCVAVLEGNEPVVIANSEGKRTTPSIVAFVEGGERKVGDPAKRQAITNPEKTIFSIKRFMGETYDQVQKEINRVPYKVVRGDNNTPRVDIEGRLYTPQEISAMILQKMKKTAEDYLGQEVTEAVITVPAYFSDAQRQATKEAGEIAGLTVRRIVNEPTAASLAYGLDKTNKDMKIAVFDLGGGTFDISILELGDGVFEVKSTNGDTHLGGDDFDHVIIDWLAEEFEREEGVDLRKDPMALQRLKEAAEKAKIELSSTTSTEINLPYIMPVNGIPKHLVKTLTRAKFEQLADGLIQACIEPCRQSLKDAGLSTSDIDEVILVGGSTRIPAVQAIVEKFFGKAPSKGVNPDEVVAVGAAIQGGVLTGEVKDVLLLDVTPLSLGIETMGGVMTKLIESNTTIPTKKSETFTTAVDNQPSVEIHILQGERSLAKDNKSIGRFHLDGIPAAQRGVPQIEVTFDIDANGILNVSAKDKGTGKVQSIRIEASSGLSDDEVKRMKEEAAANAEADKKEKERIDKLNQADSMIFQTEKQLKDLGDKLPADKKAPIEGALNKLKEAHKAQDIAGIDAAMAELNSVFQAASQEMYNAQGGGAQGGPQADPNFGGQQAGGNAGSSNNSKDGNVTDVDFEEVK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MURD_BURCM
Sequence: MFGDRQRPMVLVLGLGESGLAIARWCARHGCRLRIADTREAPPNLAALQAEGIDAEFVGGPFTPALLDGGVEIVGLSPGLSPLEPALAALIAAANERAIAVWGELEFFAQALRALGTSGYQPKVLAITGTNGKTTTTNLTGLLCQRSGKKVAVAGNISPAMLDRLARAIDETALPDVWVLELSSFQLETARTFAPDAAAILNITQDHLDWHGSFDAYAAAKGRIFGATTTRVLNRDDAAVMKFAPAAGAADAARTVTFGLNEPAQQGDYGLSRDNGIAWLVEAVDRDAPDETTSRRRKRDGAHTPDIAQKRLMPADALRIRGLHNAANALAAFALARAIDLPAAPLLHALREYRGEAHRVEVIATIDDVDYVDDSKGTNVGATVAALDGLAQKIVLIAGGDGKGQDFAPLVAPVARWCRAVMLIGRDAPAIRDTLAETGVPLADHATLEAAVHAAAELAEPGDAVLLSPACASLDMFRNYAHRADVFRAAVDEIAIDKGATT
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_PSYWF
Sequence: MQCPYCNADDTKVIDSRLAAEGAQVRRRRQCNQCQERFTTFEVVEVVMPRIIKSNGRIEPYDSQKLKRSIQLPLQKRPVTLDEQEAMISRIEKRIRQLGEREISSKGLGEVVMSELKELDDVAYVRFASVYRDFQDIEAFRQELQNIRPVDEQ
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RECF_GLAP5
Sequence: MSLSRLIINNFRNLTAVDLELNHGFNFFIGANGSGKTSLLEAIFYLGHGKSFKSHISNRIIKYNQEEFTLFGKIQEEKHECSVGLQKNRQGETILRINGESNKKIADLAYLLPMQVITPEGLTLLNGGPIYRRAFLDWGLFHQNTDFYHNWNSLKRLLKQRNAALVQTRHYNELKPWDVELSKFAQIVSQSRAVYVESILTYIEKNCQFFLPELEITATFYQGWEKERDYADLLAQGFERDRSVGYTMVGPQKADFRFRANGLPVEDVLSRGQLKLLMCALRLAQGEYFIAQKNRQCIFLIDDFASELDTQKCELLADRLYQSGSQVFVTAITQEQLKPIQGKRQDNATSFFIKDGKMQFM
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_STRPM
Sequence: MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLSQEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQKGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQGFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFAEPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_FUSNN
Sequence: MAKRDYYEVLGIDKSASENDIKKAYRKAAMKYHPDKFANASDAEKKDAEEKFKEINEAYQILSDSQKKQQYDQFGHAAFEQGGAGFGGGFNAGGFDFGDIFGDIFGGGGFGGFEGFSGFGGSSRRSYVEPGNDLRYNLEITLEEAAKGVEKTIKYKRTGKCENCHGTGGEDDKMKTCPTCNGQGTIRTQQRTILGVMQSQSVCPDCHGTGKVPEKKCKHCHGTGTAKETVEKKVNVPAGIDDGQKLKYAGLGEASQNGGPNGDLYVVIRIKSHDIFVRDGENLYCEVPISYSTAVLGGEVEIPTLNGKKMIKVPEGTESGKLLKVKGEGIKSLRGYGQGDIIVKITIETPKKLTDKQKELLQKFEESLNEKNYEQKSSFMKKVKKFFKDIID
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTRF_METMA
Sequence: MAEEHEKGVPMVLAPQMGAIDATVESIRYRAQLIARNQKLDSGVAATGIIGFAAGFLFSLLMVIVLPVAVGL
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit F, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit F.
What is the protein family that this protein belongs to?
Belongs to the MtrF family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HIS6_CLOBK
Sequence: MITKRIIPCLDVDMGRVVKGVNFVNLKDVGDPVEIAEFYNKEGADEIVFLDISATHEGRATMIDVVRKTAEKLFIPLTVGGGIKNINDFKDILRAGADKISVNSSAIRNPKLIKKAAECFGSQCVVVAIDGKKRKDKDGWNVFINGGRIDTGLDAIEWARKVEKLGAGEILLTSMDADGTKEGYDLELTNEVSKAVNIPVIASGGCGKLKHFGEIFEKSSADAALAASLFHFKELSIKEVKNYLKEEGFSVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_SALPK
Sequence: MIALIQRATRASVTVEDEVTGEIGPGLLVLLGVEKEDDEQKANRLCERVLGYRIFSDADGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSGGAAPDRAQALYEYFVERCRQQAINTQTGRFAADMQVELVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBP4_CRYNB
Sequence: MPLAMNLWSLTLLPGQQYPTYVRRDFQITNAALGEELRSKDGRSVVKVTHNPISQSMLESDDEWSDEDEDEEILSEEDDGEMEVEEVKQKKGKKAEKVEEEDSEEEDEDESDFEDELEETNVLCSLTAGKTEQASLNLTFVRGEVVVFEVTGDNVVHLMGNYIQQDEDSDDESDSDFDGEDDYSELYGSDDDLELDSEEEAAVAKITEIPDEPTPKTKKALPAADKKPVPEAKPAQKRKAEELESPAKEDAALSKAQKKKLAKKAKVEGEKAEEKPAAAAVAEKPATKKEAKAPQKKTLPSGLIIEDIKIGDGPVAKTGKRLGMRYIGKLTNGKQFDANTSGKPFSFVLGKGEVIRGWDEGLAGMAVGGERRLTIPAALAYGNQKIPGIPKNSTLKFDVKLVSIN
What is the function of this protein?
PPIase that acts as a histone chaperone.  Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail.  Proline isomerization influences H3 methylation thereby regulating gene expression.
What are the official names of this protein?
FK506-binding protein 4, Histone proline isomerase, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: VSP4_DEIAC
Sequence: MVLIRVLANLLILQLSYAQKSSELVIGGVECDINEHRFLAAFFKYQPWTFQCAGTLIHEQWVLGAAHCYKRGLNIYLGMHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVMLLKLNKPVRNSTHIAPLSLPSSPPSIGSFCRVMGWGIMSSTKDILPDVPHCANIKLVNYTECVAPYPNIPVTTRLWCAGVLEGGIDTCHQDSGGPLICDGQFQGIVAFGRYPCAQPRVPALYTKVSNYTDWIQNIIAGKTTTACPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease Dav-X, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TCHL1_BOVIN
Sequence: MPQLLRDILCVIETFHKYAREDAATLTCTELKQLIQSEFEDIFQPCAIHAVERNLNLLNIDSNGAISFDEFVLAIFSFLNVCYLDTQSLLNSEPRQVSKPEGMPHDMGLQVTNETDQWTEGTSQTQDKVVLPSGTASSTHLSLEERAVEHNRVDPQGHTTAHKLPVETSEHSDSKNQHLKGDEQSQKVDQDVSATGDSRTQRETSKPMAGSEQISSHTKGEGQNKEILQKGDILARKQSGTETGGRFGEQEGSLGILHSPLEETTQRPGGSSEDQEVAGEKGVKGHPKSQEPSVQGKDEPSSEHVDLPKQAAARKPSQTQKSAAAKDESRTAETPEPPIQEKEYETRDLSVQGENRNVSETPMVRVERKGVRGPEVHQTVGQKQIEEKTQPPALEEPTEDKKYHELQESSKEKNAGEDSETHELNSEGGEQKDSESEGAISPGEEARHAEEGTAEALVNSKNAPEAEGTPGTRERIWELTTLENQSGEKNKMTTKIHDKLVKEDDGYQGEGSEPVATQNDERSPETPNSLTAEDGDSNSETSDLFVQGDSQSQTNPFRGSVQGSDSNNPETQKHLALSEEKRVQEAAVLAVRGEDEQVTEEHAQEHEGQGSATTGRGPAVEPRGHSDTQVFIVRDENTKSLEPGIPGAPNAGITKQLSVRQLPTKKDSRKELKDQSPSTKKEEDGALEAQEDLVKSLDENNAVSQKTCPATLEEETESPQQLAGEQSLSTKEHDPSVSESGLEERMQRDQELCLVERGAEHSSPLYEALQEKMLQQTNVTQGEHQNQAQTASVASPEIRRNQSSASLTNDSSDGLVFFIDRQALQKYIREFLPDEDPTGAQQISAPQALEDKQGRPQREELEPQKEASAPKQ
What are the official names of this protein?
Trichohyalin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.