PharMolix/UniProtQA huggingface dataset:
Protein: CYB_AONCI
Sequence: MTNIRKTHPLAKIINDSFVDLPAPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMFPETWNIGIILLFTTMATAFMGYVLPWGQMSFWGATVITNLLSAVPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAIHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDVLGALLLILMLMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAVVPLLHTSNQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEYPFIAIGQLASILYFMLLLVLMPIASIIENSLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GA2PE_DROME
Sequence: MAMLEARPYRPFKSSEEYLEAMREDLAEWLSTLYPELSINADNFMDRLDTGVALCKHANYVRQAAVDYLARRQARNKSMTRSMTSGLAGPILAMGNVHYLPAAKSGTFFARDNVSNFITWCRKSLKIIECLLFETDDLIMRKNEKHVILCLLEVARRGAKFGMLAPMLVQMERQIDREIAADIKANGAGCSENGTQTDALETGNSSAATMTTITTTTVETDLYDDSDDSETEDDGDQNPVLMYGPQPQIITNDLKSLDEMVRDLVEKCTCPSQFPMVRVSEGKYRIGDTKVLIFVRILRSHVMVRVGGGWDTLSHYLDKHDPCRCRAQHRSSVAARLIPRQSPNHNPSNGIELHKAQVIFERSPPAARRVFNSPNCNGGPGTGSSCGTGVVGVAVPPTLQNGHSLSPNSGKYRSRSPTPQRKFLNQQANGGGIASATGSSQTVTTDTSSGQLLGSPSLARRSMSPSPRRLIDMRKKQSSLDSYSSGPKSLPGYSCSMEEANGGSGVGSAAGGVSSGSAGSGVAGEQGGANKFENISDNGSEISDEGYRSLGVIQSGAQKRESLHSQASIEDAESNARLDQTSSDSQISPSDEPAEKATTDILEEEDLNGQDREEDQEDYSVCDGPQSLPAILSGAHKLSDKFEQSGVFITDDEITVDIAKTEDQSVANTMGNPTPNLSKIPRSPLAQRRRRSIDNSTCGGAGGSLQDLSSRSGLPAPAFSRKQPVYRSVRTRNSTGATTTPVAPPRSRQATQLPMVRDVTNTWSGRTTGAPKRRPPCTADTFVAPTNGTGPAGSFERNGKGRSSQILYDSNGRRVRSGAPGCTSSLTTSPVKNHASSPLAQQLLEAASSAKNDAQILEKMKSLLSRYAAGNQTKAGVGATATAANKINSNGKKTPVYEDFTTAWVHSNGNLERSESCSPPAKARSKRSSAASSCESNNSNAGAGSGAAAGSASVVSPRRERGMSKIPAPVRHHTELY
What is the function of this protein?
Essential for development and viability.  Required for ovary development and oogenesis, and is essential for the development of the indirect flight muscles.  May act as a negative regulator of the Notch signaling pathway in certain tissues, such as the muscle precursors and ovaries.  May function as a linker protein between the actin and microtubule cytoskeletons.
What are the official names of this protein?
GAS2-like protein pickled eggs.
What is the protein family that this protein belongs to?
Belongs to the GAS2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=In the cytoskeleton associates with both actin and the microtubules.
Protein: SRX_DROME
Sequence: MEFISHFLRATSRRTAALGPILQRNRSEIIQKQSLTNRQAFRRYRSSCSTMDTTVHSAGIDETHLVPMSVIQRPIPSVLDEQKVQSLMETIKNETSEDEVPPIDLLWISGSEGGDYYFSFGGCHRFEAYKRLQRPTIKAKLVKSTLGDLYHYMGSSAPKYLA
What is the function of this protein?
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin.  May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity).
What are the official names of this protein?
Putative sulfiredoxin.
What is the protein family that this protein belongs to?
Belongs to the sulfiredoxin family.
Protein: RL121_ARATH
Sequence: MPPKLDPSQIVDVYVRVTGGEVGAASSLAPKIGPLGLAPKKIGEDIAKETAKEWKGLRVTVKLTVQNRQAKVTVVPSAAALVIKALKEPERDRKKVKNIKHNGNISFDDVTEIARIMRPRSIAKELSGTVREILGTCVSVGCTVDGKDPKDIQQEIQDGEVEIPEN
What is the function of this protein?
Binds directly to 26S ribosomal RNA.
What are the official names of this protein?
60S ribosomal protein L12-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RNPH_RICCN
Sequence: MRQSGRKSNQLRPISLELSPLINAEGSCLIKIGNTHVMCSATCETTVPPFLRGQNQGWITAEYGMLPGSTSQRIKREAALGKQGGRTQEIQRLIGRAMRCVIDVRKLGERQIIIDCDVINADGGTRTAAITGSYVALHLAIRSLMKKRVLKVNPLISQIAAISCGIYKGEAILDLDYLEDSDADVDSNFVFAGNGNLIEVQGTAEKNPFSEEQFLAMLKLAKGGAAELFKLQNQVLLGS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: EAA3_CAEEL
Sequence: MGMKKDLLLVLTIESVVLGVVLGFVIRPFNPSNDTISLIGFPGEIFMQIVEMMILPLIMSSVISALAQVRARDARRIGIVTIIYYMITTFLATFTGIILVSSIHPGDPELIHELGEGTLENTALSTLDTFLDQIRNMFPENIIQATFQQVQTEYMPIKPSRVRNATSMNMTSEVLHKQTLTYTNEMNVLGLIVFCSGFGIILSILGDQARLMINFFIVLDAIIMRWISALMWCYPIGILSLVCKNIIDIDNLTETAQALAMYVVTVICGLMIHSLLTLPLLYFLVTKKSPFAFMTGMLQALATAFGTASSGATLPVTFRALEENLKIDRRVTRFVLPLGATITMDGTALYEAVAVIFIAQLHNIKLSLMDLVTISITTTVASIGSGSVPAGLDTIVIVLTTVGLPAKDLSLLLTVDWLLDRIRTSVNVLGDSFGAGIIHHLTRSSLLEADTDELIRQIREDIDILNNPHQDTLPISHHSVQSTIQNTQNAMQAPHVYSKSARASFAPIPNEEERKALLKESIALNKSDTHIV
What are the official names of this protein?
Putative sodium-dependent excitatory amino acid transporter glt-3.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TVP23_ASPTN
Sequence: MEQEPLQPRQGDLNWRLSAHPVTLLCFLGIRLSALLMYLFGILFIKHFILVFIITLLLLAADFYYLKNIAGRRLVGLRWWNEVNTTTGDSHWVFESSDPNTRTITATDKRFFWLSLYVTPAFWIGLAILAVIQLSVIWLSLVVIALVLTITNTVAFSRCDRFSQASTFANRALSGGIVSNIAGGLLGRLFK
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein tvp23.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RFRNP_PYRFU
Sequence: MIRFILDTSIFVNPDVRKKFGNTPTEAMKTFLKYAEKLFGKVEFYMPPGIYKEVKNFLEDIPPEMELYIIKKPPNVHDIKIPAFVVYELIEDIRRRVDKGLRVAEKAVRESVIDTNNVDKIIQKLRRNYRKALREGIVDSTEDFELILLAKEIDGIIVSADVGILTWAEKMGIKWVDAFKFKELLDELVEKVESEKERK
What is the function of this protein?
RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.
What are the official names of this protein?
RNA-free ribonuclease P, RNA-free RNase P, Protein-only RNase P.
What is the protein family that this protein belongs to?
Belongs to the HARP family.
Protein: CAPP_AZOC5
Sequence: MTSAVWAVVSEQEAGGPDKDQPLRDDIRLLGRILGDTVREQEGDAIYELVETIRQTSIRFHRDADEAARQELNALLESMTPEVAVQIIRAFSYFSHLANIAEDQHHSRRNRAHAVAGSAPRPGTLANALARAEKAGIGAAELRAFFDAALVSPVLTAHPTEVRRKSTMNREMEIADLLDLKERLQATPQEAREQDEKLRRAVLTLWQTALLRKFKLTVLDEVQNGLSYYDYTFLAEVPRLLCALEDHLAEQEGGEPGAELPPFLRIGSWIGGDRDGNPFVTADVLRETVRQHRDRVMAFYLEQVGLLVTELSLAKRLVAVSEDLTALAERSGDRAPEHREEPYRLALVGIHNRLKATVAAQKAADDGKTMGAAEDGHLPYPDAAAFRADLDILYRSLMANGSAILARGRLRHVRRAVDSFGFHLASLDLRQNSDVHERTVADLLEQAAPGTNYHALDEEARIAVLRAELTNPRPLASPFLSYTEETRSELAILRTAAEAHARLGKTVIPNAIISKAEGISDMLELALLLKEVGLVSATGESAINVIPLFETIGDLQACGPVMDRLLALPEYRALVDSRGGEQEVMLGYSDSNKDGGFVSSGWELYKAEIALIEVFARHKVKLRLFHGRGGSVGRGGGPSYDAILAQPAGAVSGQIRITEQGEIISSKYSNPENGRRNLEILVSATLESTLLEAEQASPRPEFLAAMEELSKTAFTAYRSLVYETPGFEDYFWSSTVISEIATLNIGSRPASRNKTRAIEALRAIPWVFSWSQCRLMLPGWYGFGTAIAAFVEARPVDGIAFLQSMYREWPFFRTLLSNMDMVLSKSSLAVASRYAELVPDEELRTRIFSRISAEYQSAITSLLAIMGQKKLLEANPLLDRSIRNRFPYLDPLNHIQVELLKLHRSDAGSDHVLHGIQLTINGISAGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: URK_HAEIE
Sequence: MSNPSCIIIAITGASASGKSSISSTVHKELCNELGCQEIGIITEDSYYKDQSHLEMTERVKTNYDHPSSMDRDLLIQHLKNLKNGSAVDVPVYSYVEHTRTNETTHFTPKRIVILEGILLLTDERVRQLADISVFVDTPLDICFIRRLQRDMEERGRSLQSVIDQYRATVRPMFLQFIEPSKQYADIVIPRGGKNRIAINMLKAQILHLLNQK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIF_BACSU
Sequence: MTGRYSRQELFAPIGPSGQKKLKEARAVIIGAGALGTASAEMLVRAGVGSVKIADRDYVEWSNLQRQQLYTEDDVKKEMPKAAAAERRLRSINSDVDVTGLVMDVTAENIFELIRDASIIVDAADNFETRLIVNDAAVKEGIPFLYGACVGSYGLTFTVVPGSTPCLHCLLDALPIGGATCDTAGIISPAVLQVAVFQVTDALKLLTGEECEPVLRSFDLWKNERSEVRAASLKHDACPSCGTKDFPFLSYENQTKAAVLCGRNTVQIRSSITKEADLEALAGQLRQAGLEVAANPYLISCRSDDMKMVLFRDGRALIHGTNDIARAKSIYHKWIG
What is the function of this protein?
Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS.
What are the official names of this protein?
Sulfur carrier protein ThiS adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the HesA/MoeB/ThiF family.
Protein: RL9_VIBC1
Sequence: MQVILLDKIGNLGGLGDTVNVKSGYARNFLIPQGKAVMATKGNVEMFEARRAELEAKVAEQLAAAEARAEKVNALEAVVLASKAGDEGKLFGSIGTRDIAEAITAAGVEVAKSEVRLPEGALRNTGEFEISVQLHSEVFATINLQVVAAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RTE1_ARATH
Sequence: MSRGRGVPMMDLKRSYDVEDRVVSVSIPSIIEADEADLWPLPEIDTKKSKFPCCIVWTPLPVVSWLAPFIGHIGLCREDGVILDFAGSNFINVDDFAFGPPARYLQLDRTKCCLPPNMGGHTCKYGFKHTDFGTARTWDNALSSSTRSFEHKTYNIFTCNCHSFVANCLNRLCYGGSMEWNMVNVAILLMIKGKWINGSSVVRSFLPCAVVTSLGVVLVGWPFLIGLSSFSLLLFAWFIIATYCFKNIIT
What is the function of this protein?
Acts at an early step in the ethylene signaling pathway.  Positively regulates ETR1, leading to the negative regulation of ethylene responses.
What are the official names of this protein?
Protein REVERSION-TO-ETHYLENE SENSITIVITY1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: NUOH_CHLP8
Sequence: MSSSPSLNTWSDALSGLSIGWFPLGLVIIAAIPLVFIALYALTYGVYGERKISAFMQDRLGPMEVGIWGLLQTLADILKLLQKEDIVPKLADKFLFVIGPGILFVGSFLAFAVLPFGPAFIGADLNVGLFYAVGIVAIEVVGILAAGWGSNNKWALYGAVRSVAQIVSYEIPASIALLCAAMLAGTLSMQQITMMQAGPGGFMHWFLFTNPIAWLPFLIYFISSLAETNRAPFDIPEAESELVAGYFTEYSGMKFAVIFLAEYGRMFMVSAIISIAFLGGWTSPLPNIGGLELNTMTSGPVWGAFWIIMKGFFFIFVQMWLRWTLPRLRVDQLMYLCWKVLTPFSLIAFVLTAIWVINH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PUR5_BACCQ
Sequence: MANAYKQAGVDIEAGYEAVSRMKKHVQTTMRKEVLGGLGGFGGMFDLSKFALEEPVLVSGTDGVGTKLMLAFMADKHDTIGIDAVAMCVNDIVVQGAEPLFFLDYIACGKAEPSKIENIVKGISEGCRQAGCALIGGETAEMPGMYSTEEYDLAGFTVGIVDKKKIVTGEKIEAGHVLIGLASSGIHSNGYSLVRKVLLEDGELSLDRIYGRLELPLGEELLKPTKIYVKPILELLKKYEVYGMAHITGGGFIENIPRMLPEEIGAEIELGSWEIQPIFSLLQEVGKLEEKEMFNIFNMGIGMVVAVKEEDAKDVVRLLEEQGETARIIGRTVQGAGVTFNGGTAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_CROS5
Sequence: MPQPRKRFAQHWLRSETALEQIIQAANLKKSDRLLEIGPGTGILTRRLLPLVQSLIAVELDWDLCKKLVKSLGDEDNFLLLQGDILKLDIATEAQQFPKFLPINKVVANIPYNITSPILDKLLGRISSPKQPSYDLIVLLIQKEVAQRIIAYPGSKNYGALSIKMQYLADCNYICDVPKKSFYPPPKVDSAVITFRPRSLLNSATNPKYLETLINLGFSSRRKMLRNNLQSLIDRDLLTEFLTEIDLNEQVRAENLDLNQWIALSNYFSQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDS23_CANGA
Sequence: MTNPKNVVPNSGTSSRHASIVEMLSSPPLLPHQHAQHAHVHRSQGRSESIESIPLQRSASGTSSITSMGSNNDSSSANAQSANPSAGSATNVGASGTPHSGSGLEAGNTDLSAVPMLQTPSQCLNSAHIHTWKHIQLSQLIEQNKLIFVPGSLSVEETFNTLIKYHLTSIPVEAVPGDMNCLTFDYNDLNSYLLLVLNKITINNKQVTQDCQNGKPVAVGDIVKLTPKNPFYKLPETENLSTVMGILGSGVHRVAITNPEMTQIRGILSQRRLIKYIWDNARSFGTLEPLLNSSLQDLKIGVLNTNSKPTSRQSRVISIQGEEPLIMALYKMHKERISSIAVIDPQGNLIGNISVTDVKHVTRTSQYPLLHKTCRHFISVILNSRGLETGKDSFPIFHVYPTSSLARTLAKLVATKSHRLWIVQPQEAPTATSSSSTSSSVNTGTISPNPTPTTTSASPAPGATPNALNNHSPLLSTVDDGHTVINPATQATNTTVIQPNLFEKEYRTGKLIGVVSLTDIINLLARKQTANTEVDPQTARRQRGPATQ
What is the function of this protein?
Involved in DNA replication and cell separation.
What are the official names of this protein?
Protein SDS23.
What is the protein family that this protein belongs to?
Belongs to the SDS23 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y820_METJA
Sequence: MDDFDKETAIKFMDFLAEEILNKKLSEDEKELIYSYVGGKPINRNCY
What are the official names of this protein?
Putative uncharacterized protein MJ0820.
What is the protein family that this protein belongs to?
Belongs to the archaeal ATPase family.
Protein: LDH_GEOSW
Sequence: MKRQCMNRVALIGTGFVGASYAFALMNQGIADELVLIDVNKEKAEGDVMDLNHGKVFAPKPMNIWHGDYQDCQDADLVVICAGANQKPGETRLDLVDKNMNIFKTIVDSVMRSGFDGIFLVATNPVDILTYATWKFSGLPKERVIGSGTILDTARFRFLLSEYFQVAPTNVHAYIIGEHGDTELPVWSHAEIGSVPIEQILSQNDRYRKEDLENIFVNVRDAAYQVIEKKGATYYGIAMGLVRITRAILHNENAILTVSAYLDGQYNEQNVYIGVPAIINRNGIREVMELKLNETEQQQFHHSATVLKDILSRYFDDVK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_MYCUA
Sequence: MTLQAAPRSAAAQQREPDLRQEVHDAARRARVAARLLAVVPTGVKDRALHAAADAILAHVDRILSANAEDLDAARAADTPAAMLDRLALNPQRVDGIAAGLRQVAGLPGPVGEVLRGYTLPNGLQLRQQRVPLGVVGMIYEGRPNVTVDAFGLTLKSGNAALLRGSSSAARSNEALVNVLRSALDSEQLPADAVQLLSSADRSTVTHLIQARGLVDVAIPRGGAGLIDAVVRDAQVPTIETGVGNCHVYVHEAADLDVAERILLNSKTRRPSVCNAAETLLVDAAIAEHAMPRLIGALQDAGVTVHLDADEQDLRREYLAMEIAVAVVDGVDGAIAHINEYGTGHTEAIVTTNLAAAQRFTERIDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPELTSTKWIVRGEGHTRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_VARVI
Sequence: MAHPVQLGFQDAASPIMEELLYFHDHTLMIMFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAAILILIALPSLRILYMMDEITSPSLTLKTMGHQWYWSYEYTDYENLCFDSYMTPCSDLKPGELRLLEVDNRVVLPTELSIRTLISSEDVLHSWTVPSLGVKTDAIPGRLNQATLMASRPGVYYGQCSEICGANHSFMPIVLELIPLKHFEEWLLFTL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KHSE_BURMA
Sequence: MAVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFENLTAGQLPFYVDLMSHLAKHGVPVPAPVARDDGTLFGELHGKPAAIVTKLEGAAQLAPGVEHCVEVGQMLARMHLAGRDYPRHQPNLRSLPWWRDTVPAIAPFVTGEQRALLEGELAHQAAFFASDDYAALPEGPCHCDLFRDNALFAHAEPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWCVDLPTGALDAARADALLRAYQTVRPFTAGERRRWGDMLRAGAYRFWVSRLYDFHLPRAAQMLKPHDPGHFERILRERIAHAGALPETHACN
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: MNMG_SALTY
Sequence: MFYQDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVSRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIHGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEMGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAESADEVNAHLTTPLSREASGEDLLRRPEMTYAQLTSLAAFAPALEDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAA11_RAT
Sequence: MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDEDGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFSAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLAQMADELRRQLVLKKSRYVVLGSEENQEAQDSTLPDAEEACQPENPAGKGSEACQPENPAGKGSEACQPENPAGKDTGSHSTDVQDSSEYLDSTS
What is the function of this protein?
Displays alpha (N-terminal) acetyltransferase activity.  Proposed alternative catalytic subunit of the N-terminal acetyltransferase A (NatA) complex.
What are the official names of this protein?
N-alpha-acetyltransferase 11, N-terminal acetyltransferase complex ARD1 subunit homolog B, NatA catalytic subunit Naa11.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ARD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CONII_CONST
Sequence: MAMNMSMTLCMFVMVVVAATVIDSTQLQEPDLSRMRRSGPADCCRMKECCTDRVNECLQRYSGREDKFVSFCYQEATVTCGSFNEIVGCCYGYQMCMIRVVKPNSLSGAHEACKTVSCGNPCA
What is the function of this protein?
Potently and selectively blocks the desensitization of ionotropic glutamate AMPA receptors (GRIA1, GRIA2, GRIA3 and GRIA4) (PubMed:19481459, PubMed:35377397).  Binds to a different site than does the drug cyclothiazide (PubMed:19481459).  The toxin acts like a straitjacket on the 'gating ring' of the ligand-binding domain (LBD) of the receptor (PubMed:25103405).  It does so by restraining the domains via both intra- and interdimer cross-links such that agonist-induced closure of the LBD 'clamshells' is transduced into an irislike expansion of the gating ring (PubMed:25103405).  Compared to other desensitization blockers, it is a poor stabilizer of the open channel because toxin-bound AMPA receptors undergo frequent brief closures (PubMed:35377397).  In vitro, application of the toxin to hippocampal slices causes a large and rapid increase in resting AMPA receptor-mediated current leading to neuronal death (PubMed:19481459).
What are the official names of this protein?
Con-ikot-ikot, CII.
Protein: RPOC_AZOC5
Sequence: MNQEVMNLFNPTTPAPTFDQIKISIASPEKISSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMTLKDLERILYFEYFVVTEPGLTPLKYRQLLSEDDYLRAQDEYGEDSFTAMIGAEAIRELLRSMDLEKLAADIRVEIANSTTELKPKKLAKRLKIVEAFQASGNKPEWMILTHVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYARLDAKGHSATVKQAKKLVEKERPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGAPIIVPSQDIVLGLYYLSLMREKEPGEGMMFADMGEIDHAIAAKAITLHTKIRGRYIGVDADGKRYSKIYETTPGRMKIGELLPKHHKVPFDVVNKLMTKKEISNMIDTVYRHCGQKESVIFCDRLMSLGFYNAFRAGISFGKDDMVVPAKKWQLVEETRTLTKEYEQQYNDGLITQGEKYNKVVDAWGKCTDRIADEMMKEISAVKKDPETGREKQINSIYMMSHSGARGSPAQMKQLAGMRGLMAKPSGEIIESPIISNFKEGLTVMEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDSIINERDCGSNNGIHMRAIIDSGQVVASLASRVLGRTAVEDVVEPATGDIIVPKGTMIEEHHIERINKSGIQEIKIRSVLTCETRNGVCGTCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQLADSSFVETNFEGTVRVRNRNVARNSEGDLVVMARNLAIVVVDHDGTERAVHRIQYGSRLKVDEGDTVKRGQRIAEWDPYTRPILTEVDGTVGFEDLVEGQSMSEAVDEATGIAKRVVTDSRSVRGADLRPAIVLKGKDGKVSKLPRGGDARYTLPVEAIISVDPGQTIKAGDVVARVPMESAKTRDITGGLPRVAELFEARRPKDAAIIAEISGTVRFGRDYKNKRRLTIEPTEGGDAVEYLIPKGKHIHLQDGDVVEKGDFLVDGNPAPHDILAIKGVEELAAFLVNEIQEVYRLQGVNINDKHIEVIVRNMLQKVELDDAGDTEFLDGEQVDRIELAEANERMKEQGLKPATGHPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKVDPLDGLKENVIVGRLIPAGTGAQMNKLRVTANSRDDLILATRGESEEPSMVEGSADAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.