PharMolix/UniProtQA huggingface dataset:
Protein: NDL3_ARATH
Sequence: MVGLNNAVSLDIEEICNGGKEHHVKTCHGSVSVVVYGDQEKPALITYPDVALNYMSCFQGLFLCPEAVSLLLHNFCIYHISPPGHEFGAAPVCSNDPSPSVEDLADQILEVLNFFSLEAVMCMGITAGAYILSLFAIKHKERVLGLILISPLCKAPSWSEWFYYKVVSNLLYYYGMSGLLKDIFLQRYFSKEARGSSEVPERDVVHECRRLLGERHGSSLMRFLEAVNRRHDLTDGLKSLKCRTLIFVGDQSPFHSETLHMVTALDRKYSALVEVQACGSMVTEEQPHAMLIPMEFFFMGFGLYRPGRVSDSPRSPLSPSCISPELLSPESLGLKLKPIKTRVPTKC
What is the function of this protein?
Involved in a signaling pathway that modulates root auxin transport and auxin gradients.  Acts partially by positively regulating the auxin carrier PIN2 and AUX1 (PubMed:19948787).  Acts, together with GB1 as positive regulator of meristem initiation and branching.  GB1 and NDL3 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots, which regulates organ and lateral meristem formation by the establishment and maintenance of auxin gradients (PubMed:24223735).
What are the official names of this protein?
Protein NDL3, Protein N-MYC DOWNREGULATED-LIKE 3.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_SALTY
Sequence: MQTVLAKIVADKAIWVEARKQQQPLASFQNEIQPSTRHFYDALQGARTAFILECKKASPSKGVIRDDFDPARIASIYQHYASAISVLTDEKYFQGSFDFLPVVSQSAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLSAVAHSLKMGVLTEVSNDEERERAIALGAKVVGINNRDLRDLSIDLNRTRQLAPKLGHGVTVISESGINTYGQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVCGLTRAQDAKAACDAGAIYGGLIFVPSSPRAVSVEQAREVISGAPLQYVGVFKNADIADVCQKAAVLSLSAVQLHGSEDQAYVNALREALPKQVQIWKALSVSDALPARDYHHVDKYIFDNGQGGSGQRFDWSLLQGQPLDNVLLAGGLAADNCVQAAQVGCAGLDFNSGVESQPGIKDARLLASVFQTLRAY
What is the function of this protein?
Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway.  The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity).
What are the official names of this protein?
Tryptophan biosynthesis protein TrpCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the TrpF family.
Protein: SMAG1_XENTR
Sequence: MMFRDQVGMLSGWFKGWNECEQTVALLSLLKRVSRTQARFLQICLEHSLVDCTELHILEGEANNPAIINQWQQESKDKVISQLLTHLPLLKPGNIDAKVAYMKLLPKILAHSIEHNQHIEESRQLLSYALIHPATSLDDRSALAMWLNHLEDRTSGNFSTQSRCRSDSLDYGQMQYYHQRQNSDDKQNGWPNSRDSGICVSSSGWQEKNTGCENGHLPLYSSSSVPSTINAIGTNTSTILSGQTHHSPLKRSVSLTPPMNVPNQPLGHGWMSHEDLRARGSQGIPSDHAPLSPQSSVASSGSGGSEHLEEQSTARNTFQDEGSGMKDVPAWLKSLRLHKYAALFSHMSYEEMMSLNECQLEAQNVTKGARHKIVISIQKLKERHNLLKTLERDILEGGNLRVPLQELHQMILTPIKTYSPQNSNTEEHNREADSQPTLLVAENQASESKDSASAGIQQHHISNCETESGGVPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCLTHEAFTETQKKRLLSWKQQVQKLFRSFPRKSLLDVAGYRQQRKTSVDVLIGSRAFGQSNSLPTAGSVGSGIARRNPRQFQIPSRNLPSTRLSLLGASSLLGAPQRASASNPAMLKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQTMLMFQQPDFQVPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI
What is the function of this protein?
Acts as a translational repressor.
What are the official names of this protein?
Protein Smaug homolog 1, Smaug 1, Sterile alpha motif domain-containing protein 4A.
What is the protein family that this protein belongs to?
Belongs to the SMAUG family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Synapse, synaptosome.
Protein: PCKA_GEOSM
Sequence: MRFNDITRGSGLEQHGITNPNLIYWTSPTSVLYEQVVRRGEGLISHLGALTVKTGHYTGRAANDKFIVDEPESSSRINWGKVNRPFPPESFDHLYKKMTSYMQGRDLFVQDCFAGASPEHRIPVRIITERAWHALFARNMFLRATQEELLTHNTEFTVIDLPAFHAQPKVDGTNSEAFIIINFARKLVIIGGTSYAGEIKKSIFTVLNYLLPQKGVMSMHCSANAGEKGEVAIFFGLSGTGKTTLSAAPNRLLIGDDEHGWDDAGVFNFEGGCYAKVINLSPQSEPEIYQCTRKFGTILENVAIDTISRRIDLDDASFTENTRASYPITHIPNIVGEGCGGHPNHVIMLTCDAFGVLPPIARLTPAQAMYHFLSGYTAKVAGTEAGVTEPQATFSACFGAPFMALRPSLYADLLGKKIASHKVSCWLVNTGWSGGGPGIGGRMKIAYSRALVNAALDGTLGAGSFVKDSVFGLDIPSACPGLPADILNPRNVWSDKSAYDATAHKLVEMFRHNFEQFKATTSPEIASVL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHP6B_YEAST
Sequence: MAATKEAKQPKEPKKRTTRRKKDPNAPKRGLSAYMFFANENRDIVRSENPDVTFGQVGRILGERWKALTAEEKQPYESKAQADKKRYESEKELYNATRA
What is the function of this protein?
DNA-binding protein that induces severe bending of DNA.  Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex.  Required for transcriptional initiation fidelity of some but not all tRNA genes.  Seems to be functionally redundant with NHP6A.
What are the official names of this protein?
Non-histone chromosomal protein 6B.
What is the protein family that this protein belongs to?
Belongs to the NHP6 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PROA_ACIBT
Sequence: MQDSIEQYMQKVGQQARDASRVLTSASTSLKNHALSAIYTALENNQAAILAANQIDMEKGRSNQLDSALLDRLELTPARFKGMLQGLKDVIVLVDPIGEITDLAYRPTGIQIGKMRVPLGVVGMIYESRPNVTLEAASLAIKSGNAIILRGGSEALESNKAIAEAVKHGLKVAGLPEHSVQVIETSDRGAVGHLITMAEYVDVIVPRGGKSLIERVTNEARIPVIKHLDGNCHVFVEAQADLQKALPITLNAKTHRYGVCNAMETLLVDEKIAEVFLPHIAELYAEKQVELRGCPETRRILGSSVKPATEEDWYTEYLGPILAVKVVSGIDEAIDHINKYGSHHTDAIVTENYTLARQFLARVDSSSVVVNASTRFADGFEYGLGAEIGISTDKIHARGPVGLEGLTSQKWIVLGDGQIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_BACCR
Sequence: MNEQQRLASQQANSSTKKEEKDYSKYFESVYQPPSLKDAKKRGKEEVKIERDFGLPEEFRNFGTGRKFYIRTYGCQMNEHDTEVMAGIFTALGYEPTFSTEDADVVLLNTCAIRENAENKVFGELGHLKSLKRRNPDFLIGVCGCMSQEESVVNKIMQKNQHVDMVFGTHNIHRLPYILKDAMFSKETVVEVWSKEGDVIENLPKVRRGDIKAWVNIMYGCDKFCTYCIVPYTRGKERSRRPEDIIQEIRHLAANGYKEITLLGQNVNAYGKDFEDIEYGLGDLMDELRKVDIARIRFTTSHPRDFDDHLIEVLGKGGNLVEHIHLPVQSGSTDMLKIMARKYSREHYLELVRKIKEAIPDAVLTTDIIVGFPNETDEQFEETMSLYREVGFDTAFTFIYSPREGTPAAKMKDNVPMEVKKERLQRLNTLVNTLAIEKNSRYKGQIVEVLVDGESKNNPEVLAGYTRTNKLVNFVASKSLIGQLVKVKITEAKTWSLNGELVEEPIEVK
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_LEGPL
Sequence: MIPVYDYLVLGVILFGLSLVGIMLNRKNIILLLVCVELMLLAVNTNFIAFSHYYNEVGGQVFVFFILTVAAAEAAIGLAIVMLLYRNRGNIDVDKMNHLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUCR_SINFN
Sequence: MTETTLGASNELLAELTAEIVAAYVSTHVVPGAELPTLIADVHSALNNATAPAPVIAPIEKPKPAVSIRKSVQDDQITCLECGGAFKSLKRHLMTHHNLSPEDYREKWDLPADYPMVAPAYAEARSRLAKEIGLGERRKRRGK
What is the function of this protein?
Could be involved in the regulation of exopolysaccharide synthesis.
What are the official names of this protein?
Transcriptional regulatory protein MucR homolog.
What is the protein family that this protein belongs to?
Belongs to the ros/MucR family.
Protein: NDK_SALAR
Sequence: MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFRIVGTRMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLESENAVQRHRDLLGATNPANALAGTLRADYADSFTENGTHGSDSLESAQREIAFFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_PAEAT
Sequence: MRTLVVDHPLVAHKLTVLRDKNTPSPVFRQLTEELVTLLAYEATREVKTQPVEIETPVTKTVGTAFTKPTPLVVPILRAGLGMLEGMTKLVPTAEVGFLGMARDEETLDIITYAERLPEDLTGRQIFVLDPMLATGGTLREAIKFLFKRGASDVTCICLLAAPEGLSKLEEELSDANVKIVLASIDEKLNEKSYIVPGLGDAGDRLYGVAG
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RHIP1_ARATH
Sequence: MSETEATGVTDDSAPAIETETVSDAMEHTAIGVVESVEGAIEGAEKWVGDLQRTVKESKDTAMRSARSLRENSTSQFRSIQDFIPHALTQYKTYENAFFSKVTDELIYAKEHPAAAIGIGVAASLVLMRGPRRFLFRNTLGRFQSEEAQFLKAEKHVQELNMSVDLMKKESRKLLERTALAEKDMKRGLSELMNSGNDIHRLAKSVHKAECEAADLMDGLRQIPGRDAIKLRAEVASMTSLLRQKRIALNKRIMGMSDLGVSV
What is the function of this protein?
Required for some glucose-regulated gene expression, being a physical connection between RGS1 and HXK1 in sugar signaling.  Prevents roots and inflorecences growth.
What are the official names of this protein?
RGS1-HXK1-interacting protein 1.
Protein: RS2_HALWD
Sequence: MTENDNEVVEVVDDDEAVVSESPVDVDTATEAEADTETDESNETTPTASDAAGDETTTQTGNESADAEPDDELEGPTFDEDVMPDEEADLLIPVEDYLSAGVHIGTQQKTSDMERFIHRVRDDGLYVLDVSQTDSRIRTAANFLANYNPDQMLVTSSRQYGRFPAKKFADAVGARARTGRFIPGTLTNPDYAGYIEPDVVVVTDPIGDAQAVKEAITVGIPVIAMCDSNNQTSNTDLVVPTNNKGRRALSVVYWLLANETLDRRGADSLYALDEFEAEI
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MATK_TRIIC
Sequence: MKEYQVYLERARSRQQDFLYPLIFREYIYGLAYSHNWSRSIFLENGGYDNKYSLLNVKRLITRMYQQNHLIISANDSPKNGFWGYNKNFDSQIISEGFAIVVEIPFFLQLSSSLEKAEIIKSYKNVRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDAPFFHLLRLFLYHFSNWNGFITTKKSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSSHLRLKSFSVFLERIFFYAKREHLVEVFAKDFSYPLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKHYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVRADSSDFDIIERFLRICRNLSHYYNGSSKKKNLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFTLHRFYRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AMPA_ECOHS
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_FRASN
Sequence: MVVPSTAPASDDLFRRAQRVVPGGVNSPVRAFRAVGGTPRFMTSGSGPRLVDADGRTYVDLVCSWGPMILGHAHPDVVQAITAAAARGTSFGTPTPGEVELAELIVERVAPVEQVRLVNSGTEATMSAIRLARGFTGRPTIVKFAGCYHGHVDALLASAGSGVATLGLPDTPGVTGAATADTIVLPYNDLALVEATFAERGDTIAAVITESVAANMGVVPPLPGFNAGLRRLCDAHGALLVFDEVMTGFRVSRTGWWGLEGAVEGWAPDLFTFGKVMGGGLPAAAFGGRADVMARLAPAGPVYQAGTLSGNPLAVAAGLATLRACTDEVYATVDARAADVAGIVSTALNEQGVPHLLNSAGSLFSVFFTDATAVIDYAGAKRQASERYAAFFHSMLDAGVYLPPSAFEAWFVSAAHDDEAVERIAAAAPAAARAAAAVGAPVAVGGGAV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_SYNFM
Sequence: MDFRIIARDASCHARRGRLRTAHGTFDTPVFMPVGTQASVKSLSPDELEDLGAHIILGNTYHLLLRPGAERVARLGGLHRFMHWNRSILTDSGGFQVFSLARINRIEEDGVVFQSHIDGARHAITPETSMECQMQLGSDIAMCFDECTAYPVTYEYARESMLRTVRWAARSKEAHTLPEQSLFGIVQGGVFCDLRRDCLERLVETGFDGYALGSLSVGESKEEMLSVLEAVAPGLPAASPRYVMGVGTPEDLVEGVRCGVDMFDCVMPTRNARNGMLFTVRGGIQIKNSRYADDDRPIEEGCSCYTCRRFSRAYLRHLFLARELLAYRLNTLHNLHYYLGLMAAMREAIEANAFDRWRRSFYLDRENREPAEE
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: MT4_YARLI
Sequence: MEFLNANFGASLIQSKHKTTKKHNLVNSCCCSKPAEKPTNSCTCSKCACDSCKC
What are the official names of this protein?
Metallothionein-4, MT-4, MTPIV, Metallothionein-IV, MT-IV.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 11 family.
Protein: RL33_PROMH
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTMPEKLEMKKFDPVVRQHVTYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: M3H14_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGKILSGLKTALKGAAKELASTYLHRKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTKKEKRILGPVLGLVGEPLGGLIKKIG
What is the function of this protein?
Maximin-H14 shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins 3/H14.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURB_RICPR
Sequence: MSILPIIKGEYKKDYNLKHLTWFKVGGNAEIFFKPFDFADLKSFLIQNKQKLPITTFGSGSNIIIRDGGIEGVVIKLGQNFNKIEFLDNHLIVGSSCLNYNLARFCQANAISGFEFLVGIPGTIGGGVIMNAGAYGSAFQDIIVQVEALDFSGNFLTFTNKEIGFKYRGNNLPKDLILLKAVFKVNKGDSQNILLKMNKINNTRSSTQPIKERTGGSTFINPEGRKSWELIDKAGLRGYRIGGASISELHCNFMINNGNATAKDLEDLGNFVRQKVFEDSGVELNWEIKRIGKYV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNAZ_RAT
Sequence: MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein G(z) subunit alpha, G(x) alpha chain, Gz-alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: RNT_PSEU2
Sequence: MSEDHFDDEHEGHGGGGGSRHPMAARFRGYLPVVVDVETGGFNSATDALLEIAAVTIGMDEKGFVFPEHTYFFRVEPFEGANIEAAALEFTGIKLDHPLRMAVSEETAMNDIFRGVRKALKANGCKRAVLVGHNASFDLGFVNAAVARMDMKRNPFHPFSSFDTATLAGLAYGQTVLAKACQAAGIDFDGREAHSARYDTEKTAELFCGIVNRWKEMGGWQDFDD
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: CA4A_CONMA
Sequence: MGMRMMFTVFLLVVLATTVVSIPSDRASDGRNAVVHERAPELVVTATTNCCGYNPMTICPPCMCTYSCPPKRKPGRRND
What is the function of this protein?
Probable neurotoxin with ion channel inhibitor activity.
What are the official names of this protein?
Conotoxin MIVA, KappaA-conotoxin.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SHB_HUMAN
Sequence: MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQASSAASASCGPATASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGSGEPGGVQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGGGAGDPLGGACAGGRTWSPTACGGKKLLNKCAASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL
What is the function of this protein?
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components.  May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling.  May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades.  May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
What are the official names of this protein?
SH2 domain-containing adapter protein B.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associates with membrane lipid rafts upon TCR stimulation.
Protein: ACUI_RUEPO
Sequence: MFNALVVDKDEESGKTQAAVKQLSLTDLPVGEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVPGIDFAGTVENSSDERYKPGDKVVLTGWRVGEAHWGGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGFTAMLAVMALEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSLGATQIVARDEINETVKRPLESEIWAGCVDAVGGAMLARVLGQMKYGASVAAVGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYANRLRAWERIARDLPMDKLEAMIRPATLSDLPGLGADILKGQVQGRVVVDVNA
What is the function of this protein?
Probably catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA.  Restores acrylate resistance when expressed in an E. coli strain K12 acuI deletion.
What are the official names of this protein?
Acrylyl-CoA reductase AcuI, Acryloyl-coenzyme A reductase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIM5_NEUCR
Sequence: MEKAFRPHFFNHGKPDANPKEKKNCHWCQIRSFATHAQLPISIVNREDDAFLNPNFRFIDHSIIGKNVPVADQSFRVGCSCASDEECMYSTCQCLDEMAPDSDEEADPYTRKKRFAYYSQGAKKGLLRDRVLQSQEPIYECHQGCACSKDCPNRVVERGRTVPLQIFRTKDRGWGVKCPVNIKRGQFVDRYLGEIITSEEADRRRAESTIARRKDVYLFALDKFSDPDSLDPLLAGQPLEVDGEYMSGPTRFINHSCDPNMAIFARVGDHADKHIHDLALFAIKDIPKGTELTFDYVNGLTGLESDAHDPSKISEMTKCLCGTAKCRGYLW
What is the function of this protein?
Histone methyltransferase that specifically trimethylates histone H3 to form H3K9me3.  H3K9me3 marks chromatin regions for DNA methylation (PubMed:11713521, PubMed:12372305, PubMed:12679815, PubMed:12887903).  Dim-5 recognizes Arg-8 to Gly-12 of the H3 tail with Thr-11 and Gly-12 being the most important specificity determinants, the recognition of whcih is important to distinguish H3K9 from H3K27 and H4K20 (PubMed:18215768).
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5, Histone H3-K9 methyltransferase dim-5, H3-K9-HMTase dim-5, HKMT.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CCY1A_XENLA
Sequence: MGNTVTCCVSPDSSPKEGRDREVTESGEPYQAQGEPQDGDVQHMSVWELPIDLSNERNPSDDAQTSTIFLCKSQTDVREKRKSNHINHISPGQLTKKYSSCSTIFLDDSTVSQPNLRSTIKCVTLAIYYHIKNRDSDRSLDIFDEKLHPITREEVAHDYCKHDPDHKHIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPSNWKQIVLGAILLSSKVWDDQAVWNVDYCQIMKDITVEDMNEMERHFLELLQFNINVTASVYAKYYFDLRSLADDNNLHFLLEPLSNERAQKLEAISRLCEDKYKDLSKAAMRRSISADNLVGIRRSNAIIS
What are the official names of this protein?
Cyclin-Y-like protein 1-A.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin Y subfamily.