PharMolix/UniProtQA huggingface dataset:
Protein: BRCA2_DROME
Sequence: MDQNGASGSHPNRLSQGRGAHARERGATVSAAANRSNIIDEMAKICEADRQTFAIARRTRGHERLAVDNSDFVAVEDLILSYAEPTPEDQVEMIMSDFCSSPTYAEDEDEPSHESEPWFRFRNKRIRTYSRKRDPKSHKAVQNEKRRGSSGLSVQRDLNTSFTSMACDFDASSQKIHEVLLNLSQYFSATATASGPTPVPSQIDLPTEARQDSGDECFNAELENLRDDLLQSGFTFEASFYENEHEQEGPGTMADTIYGDSMQSVPTTRLRLESGKRNVWSDADSTLKKADVEIAENKKLLMGQTQAKNVDIEENTNFILEGIPLSEWLTPMELPEISKDVIKHIPDKKLKLEPSSQKEQKSSKDSNASKVRGASKQSCDINTKNEGTTILDQPNAAEQENLLNDGELLEEFLFNDWQPMQCSNGPSTSKNAIQGPKENINSINLDDKEQPEKQTPNKSQTISSHQLNGIRKKSFKFIEVSEEMKIKGEEFVDKVVSGLYHFSHKCNLRTEEYSDNHSQVMESTQCAEFKSAPSKPIEILDGKETYNAIAKVDVGEINGKFSPLNNDTIAEPEFCGFRTASNKAIPISEKMKIKTAEFMAEFQSKETIQQNDYLVHQPNDKPTSVGLDTALKRSIESSEEMRSKASKLVVVDTTMREPHQPTLDPVCRDLNESQFFGFRTASNKAIEITEAMEKRGAMFLAQSKATDQLNGWQPSDFPDVLPTSPNNEIHSINVENNKAVNTKTVSETEFFGFRTASNKGIVISENTKIKVAQFMSEFQAADASTDSNQPTVISEESRNIDAKFVDEAAAEDSANKPTFCNVQSLKNTSDIEHFKHDFFVEHSAKEEHPLCSQPLVRTPRRSQEIHSSLSQLAGKSPLDQATKKSVIARRNLLSLKRKRKIILSTETSTSCALPTMERFAPKPSSTSTPLADRDLNRSKDCTKNRQDAEDMSPICMQPKKSRRLGLSRSRY
What is the function of this protein?
Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination.  During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint.
What are the official names of this protein?
Breast cancer type 2 susceptibility protein homolog, dmbrca2.
What are the subcellular locations of this protein?
Nucleus. Note=Brca2 and spn-A/Rad51 become recruited to nuclear foci after DNA damage.
Protein: YOP1_CRYNJ
Sequence: MAAHSEQIKNNFLNNPYAQQVFNIANGQVSALDAELNKYPILRQLEQQTKVPKAYGVIALGFSSVLLIFFNMFGLAQPISNLIGWALPAYLSILAIESPQTNDDKQWLTYWVVFGSLNLVESMGLRAVLYWVPMYFVFKTLFTIWLMLPATRGAEILYFHFLRPMVGNVKSRSQSSFGTSDPLAKETGFNPAGTTAPSSFAHEKTL
What is the function of this protein?
Required to generate and maintain the structure of the tubular endoplasmic reticulum network and the vacuole.  Induces high curvature in membranes and causes membrane tubule formation.  Involved in membrane/vesicle trafficking.
What are the official names of this protein?
Protein YOP1.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: FTPA_HAEDU
Sequence: MRSKTITFPVLKLTGQSQALTNDMHKNADHTVPGLTVATGHLIAEALQMRLQGLNELALILKHAHWNVVGPQFIAVHEMLDSQVDEVRDFIDEIAERMATLGVAPNGLSGNLVETRQSPEYPLGRATAQDHLKLIDLYYSHNIEAHRVVLEHNGHLDPISEDLLVAQTRSLEKLQWFIRAHLDNGNGNI
What is the function of this protein?
May contribute to bacterial adherence, or be involved in the protection of the bacteria, or both.
What are the official names of this protein?
Fine tangled pili major subunit, 24 kDa surface protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: TRML_ECOL6
Sequence: MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRLRRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPETRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRD
What is the function of this protein?
Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA).  Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
What are the official names of this protein?
tRNA (cytidine(34)-2'-O)-methyltransferase, tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANS2_ARATH
Sequence: MANTILRGQMIFQDENALAALGKKAVAAGKGKSSLAAPKKNGAGFGSRKALHDITNKSKLQPQASSTTRKDVEGVDFDIAKEGFLHDHSKCIEEQQQDQWDSYFSEHIILHGHETNIKEGVPQYNNIQEIDAENSWDELKEIPMEEFSDLLECSTQWRSPPDSLSHHHSSLPSSPLPWHFETVEFKLKEDEDTT
What is the function of this protein?
Not required for protection of centromeric cohesion.
What are the official names of this protein?
Protein PATRONUS 2.
Protein: YC06_KLEPN
Sequence: MTSISKKKQPETVDDLDFGRMVGELIDHRKIIIALTSFATLIALLYAFFATPIYKADALIQVEQKQANAILSNLSQMLPDSQPQSAPEIALIQSRMILGKTVDDLNLQAVVSPKYFPIFGRGWARLSGEHQGNIQLSRLYVSSSIGDEENPPEFTLKVKDSNRYVIEFGGEEINGKVGELIEKDGITLKIDEINAKPGAEFTIKYVSKLKAIADLQENLSVADQGKDTGILILSYLGDDPLKIKNIVDSISENYLAQNISRQAAQDEKSLEFLNKQLPMVRSDLDSAEDKLNDFRKRNDSVDLSLEAKSVLDQIVNVDNQLNELTFRESEISQLYTKEHPTYKALMEKRKTLQDERGKLNKRVATMPETQQEILRLSRDVESGRAVYMQLLNRQQELNIAKSSAIGNVRIIDSAVTQHKPVKPKKIIVVLAGLFIGLVISVSLVLVRILLRKGIETPEQLEELGINVYASIPVSESNPKNVIAKRLNKRDDSRPKVLLATENPADLAIEAIRGLRTSLHFAMLEARNNLLMISGASPNAGKTFVSSNLSSVISQTGKKVIFIDADLRKGYTHKLFNIKNTNGLSDYLSGRVALDKIINNLQTEGFDYISRGSVPPNPAELLMHNRLAELLEWANKSYDIVILDTPPILAVADAAIIGNYVGTTLLVARFEENTPKEIDISVKRFQNSGVNIKGCILNGVVKKATNKYGYGYNYYDYSYSDKK
What are the official names of this protein?
Putative tyrosine-protein kinase in cps region, ORF6.
What is the protein family that this protein belongs to?
Belongs to the etk/wzc family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GRB14_BOVIN
Sequence: MTTSLQDGQSAAGRAAARDSPLAAQVCGAAQGRGDARDLAPAPWLHARALLPPPDATRGCAADRRKKKDLDVLEMPSIPNPFPELCCSPFTSVLSAGLFPKANSRKKQVIKVYSEDETSRALEVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHVGLERTIEDHELVIEVLSNWGMEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFLLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGYSSQSISPMRSISENSRVAMDFSGQKTRVIENPTEALSVAVEEGLAWRKKGCLRLGSHGSPTASSQSSATSMAIHRSQPWFHHKMSREEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL
What is the function of this protein?
Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways.  Binds to, and suppresses signals from, the activated insulin receptor (INSR).  Potent inhibitor of insulin-stimulated MAPK3 phosphorylation.  Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal (By similarity).
What are the official names of this protein?
Growth factor receptor-bound protein 14, GRB14 adapter protein.
What is the protein family that this protein belongs to?
Belongs to the GRB7/10/14 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein. Note=Upon insulin stimulation, translocates to the plasma membrane.
Protein: CREB_ASPFC
Sequence: MFCLLLGSTAPSVGAVPAKKEPQPPPMTPLEKRLLDMGPIREDGSDKFYGMENYGNTCYCNSILQCLYYSVPFREAVINYPTRTPIESLEAALAKSLRYPNPNAQLEAEAQAEKQKAANAQRPGMPPNPQQKPEDKDSPEYKKKMALQTLPLLETQNNASSYGMSESLFTSLKDIFESVVGSQSRIGIIRPQQFLEVLRRDHEMFRTAMHQDAHEFLNLLLNEVVANVEAEASKQPPIEKSLPAPETADSVDQSSSTGSKTPNTTRWVHELFEGLLTSETQCLTCEKVSQRDEVFLDLSVDLEQHSSVTSCLRKFSAEEMLCERNKFHCDNCGGLQEAEKRMKIKRLPRILALHLKRFKYTEDLQRLQKLFHRVVYPYHLRLFNTTDDAEDPDRLYELYAVVVHIGGGPYHGHYVAIIKTEDRGWLLFDDEMVEPVDKNYVKNFFGDKPGLACAYVLFYQETTLEAVLKEQEQENMDSNLAATDANDTILKQNGFPQSPLAHVHSASQIPSHEDNLRPNGLRRAPTAPQLSTHHEHGDPESAPFSPLSPLSPLSQTPPVPPVPERVTTVATPPKNDALAKKERAREEKERKAAEKEREKAEKLRRKEQEARMKENQRREEAELKAALEMSKASKAEEDRRLSHENGKEKQGGSLSRLKRGSKSLSHRLGKDKETRSVSSDLPPVPIPEHSTLSQTGPTSEQQQQQQQQQQQQQSPPNHDQPPNSPQLGKPTIREDEQVNHKDSKHERTGHGKWRSFSLRKKSFSILS
What is the function of this protein?
Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Deubiquitinates the creA catabolic repressor and the quinate permease qutD.  Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase creB, Carbon catabolite repression protein B, Deubiquitinating enzyme creB, Ubiquitin thioesterase creB, Ubiquitin-hydrolyzing enzyme creB, Ubiquitin-specific-processing protease creB.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: RL5_ROSS1
Sequence: MVPRLKEKYQTEVVPALMQEFRYRSVMQVPRIEKIVLNIGLGEAIQNSKALDAATADLAAIAGQKPVITRARKSIAAFKVRQGMPIGVMVTLRGPRMWSFLDRLMNLVLPRLRDFRGVSRRSFDGRGNYSIGLREQIVFPEIDYDKVDKLRGLEVVIVTTAPDDEQGYALLKRLGMPFRD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: LFTR_RALPJ
Sequence: MIAWLDPHDPFPPVDRALGPESEAPGLLAASAELSPQRLLIAYRQGIFPWYAQGQPVLWWSTDPRMVLRPEDFRVSTTFRKTLRRVLDDPAWEIRIDHAFRETMVACATTARPGQHGTWITEDVIQAYTALHRRGYAHSVETWHAGQRVGGLYGVALGRMFYGESMFAHRTDASKIALAALCAFLGGQGVAMIDCQQETEHLASLGGAPVPRAAFLAHVREAASAPAIVPWHFDKSVLRRWTVRNEQA
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST18_HUMAN
Sequence: MDAEAEDKTLRTRSKGTEVPMDSLIQELSVAYDCSMAKKRTAEDQALGVPVNKRKSLLMKPRHYSPKADCQEDRSDRTEDDGPLETHGHSTAEEIMIKPMDESLLSTAQENSSRKEDRYSCYQELMVKSLMHLGKFEKNVSVQTVSENLNDSGIQSLKAESDEADECFLIHSDDGRDKIDDSQPPFCSSDDNESNSESAENGWDSGSNFSEETKPPRVPKYVLTDHKKDLLEVPEIKTEGDKFIPCENRCDSETERKDPQNALAEPLDGNAQPSFPDVEEEDSESLAVMTEEGSDLEKAKGNLSLLEQAIALQAERGCVFHNTYKELDRFLLEHLAGERRQTKVIDMGGRQIFNNKHSPRPEKRETKCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDKNQLDSPQTGQCPDQAHRTSLVKQIEFNFPSQAITSPRATVSKEQEKFGKVPFDYASFDAQVFGKRPLIQTVQGRKTPPFPESKHFPNPVKFPNRLPSAGAHTQSPGRASSYSYGQCSEDTHIAAAAAILNLSTRCREATDILSNKPQSLHAKGAEIEVDENGTLDLSMKKNRILDKSAPLTSSNTSIPTPSSSPFKTSSILVNAAFYQALCDQEGWDTPINYSKTHGKTEEEKEKDPVSSLENLEEKKFPGEASIPSPKPKLHARDLKKELITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGCPLAAKRQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQVIKKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSNLERDYSPECKALLESIKQAVKGIHV
What is the function of this protein?
Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides.  Represses basal transcription activity from target promoters (By similarity).  Inhibits colony formation in cultured breast cancer cells.
What are the official names of this protein?
Suppression of tumorigenicity 18 protein, Zinc finger protein 387.
What is the protein family that this protein belongs to?
Belongs to the MYT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_RUEST
Sequence: MLGIGTLAKKVFGTPNDRKIKATRPLIAKINALEPEFEALSDQGIKDKTEDLRKRALAGESLDDLLPEAFANVREAARRALGLRAFDTQLMGGTFLHQGNISEMKTGEGKTLVATFPAYLNALTGKGVHVVTVNEYLAKRDSEWMSKVFGALGMTTGVIYSNQPEAEKMAAYQCDVTYATNNELGFDYLRDNMKPSLDQVFQKQHNFAIVDEVDSILIDEARTPLIISGPAEDRSELYETIDKLIPTLDEGHYEIDEKTRGVTFTDEGNEFLEESLLKAGLLEEGASLYDPESTTIVHHVNQALRAHKLFQRDKDYIVRDGNVVLIDEFTGRMMPGRRLSEGLHQAIEAKEGTDIQPENTTLASVTFQNYFRLYDKLSGMTGTAMTEAEEFAEIYGLGVVEVPTNRPIARIDEDDKVYRTANEKYAAMIAETKLAHEKGQPVLLGTTSIEKSELLSQLLQQEGIEHNVLNARHHEQEAKIVAEAGRLGAVTIATNMAGRGTDIQLGGNIDLKVMEALEANPDADPAVLRAEEEAKHAEEKQKVLEAGGLYVMASERHESRRIDNQLRGRSGRQGDPGRTSFYLSLEDDLMRIFGSERLDKLLSGLGMKEGEAIIHPWVNKSLERAQAKVEGRNFDMRKNVLKFDDVMNDQRKVVFAQRREIMASDDTHEIVTDMRHEVIDDLIDIYMPPKTYADQWDTQGLQDDVREKLNIDAPVVEWAAEEGVDDEQIRERLVEASDKLMAEKVEAFGQEGMSNIEKQVLLQTIDAKWREHLLTLEHLRSVVGFRGYAQRDPLNEYKNESFQLFESMLDSLRETVTQQLSRVRPLSEEEQREMMMQMAARQGMQRAAAPAAEPVEAPKEGFVEDDPSTWGNPSRNDKCPCGSGKKFKHCHGRLG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: Y144_AFV1Y
Sequence: MTIVNILRVDIDQPFDYLDKQFYGNLTLRKLLVWRIFYVSKVFSQHVESLEFRKSLSGNIHVLVTINPGIQRTLVPLAQFLMGDDIMRTFMNLKRKGKGNYLFSYGNTDADRFLAERQIARKQKALNRKKSKTKNGEKNGEGKS
What are the official names of this protein?
Uncharacterized protein ORF144.
Protein: GATB_NITHX
Sequence: MNAPVKPSNLIKGATGDWEMVIGLEVHAQVTSNAKLFSGASTAFGGEPNSHVSLVDAAMPGMLPVINEECVRQAVRTGLGLNAQINLRSVFDRKNYFYPDLPQGYQISQYKSPIVGEGEIVVDLADGASIAVGIERLHLEQDAGKSLHDQHADMSAIDLNRSGVALMEIVSKPDLRSSEQAKAYVTKLRTILRYLGTCDGDMEKGSLRADVNVSVRRPGAALGTRCEIKNVNSIRFIGQAIEHEARRQIGILEDGGSIDQETRLFDPDKGETRAMRSKEEAHDYRYFPDPDLLPLEFSQGFVEALKADLPELPDQKKTRFIGDFGLTPYDAAVLVGEHESANFYEAVLAGLANGRRDGKLAANWVINELFGRLNKESRGIAASPVSASQLAAIVDLIGEETISGKIAKDLFEIVWTEGGDPRTLVEARGMKQVTDMGAIEKAVDDIVAANPDKAAQVRAKPQMIGWFVGQVMKASGGKANPQAVNDLLKTKLGL
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RK2_CRYJA
Sequence: MNTRSYSTFTPGTRDKSLSSFDGKVKSHPQKKLTSGQHRCGKGRNNSGIITIRHRGGGHKRLYRQIDFRRSEKNNILGKIVTIESDPNRSAYICLVHYRDGQKTYILHPRGIMIGDTILSGPRAPISMGNALPLTNIPLGTTIHNVEVQVGKGGQLARAAGAVAELIAKEGRLTTLRLPSGEVRLISENCLATIGQVGNVKWKNRTLSKAGSKRWLGKRPEVRGVVMNAVDHPHGGGEGRAPIGRKKPLTPWGYSALGKKSRKRNKYSDVSILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFG_NATTJ
Sequence: MTRKFPLEQTRNIGIMAHIDAGKTTTTERILFYTGRVHKLGETHDGASTMDFMDQEQERGITITSAATTCQWRDTRVNIIDTPGHVDFTVEVERSLRVLDGAIGVFCAKGGVEPQSETVWHQADRYHVPRIAYINKMDIMGADFYNVVDMMNERLQANPVPIQLPIGKEDDFQGIVDLIKNTAVIYKDDLGTEWEEVEIPEDMQELAEEYRDKMLEMAAEYDEELMMKYLEGEEITSEEIRLALREGCLKTELTPVLCGSSYKNKGVQMLLNAVIDYLPAPTDVPPIEGVVPGKEDEEEKEQRVSSDDEPFSALAFKIVTDPYVGKLCFFRVYSGKIEAGSYVYNPVKGKKERVGRILQMHANHREERNVVYTGDIAAAVGLKNTSTGETLCSPEKPIVLESMQFPEPVISVAIEPKTRADQEKMATSLQKLSEEDPTFQTHTDDETGQTIIKGMGELHLEVIVDRLLREFKVEANVGKPQVAYKETIKAPTKSEGKFIRQSGGRGQYGHVLIEMEPLERGAGYEFEDKIVGGVIPKEYIPAVDNGIQEAMQNGVLAGYPMVDVKITLYDGSYHEVDSNESAFKIAGSMAFKDGSKKASPVILEPIMKVEIVVPEEYMGDVMGDVNSRRGRIEGMEERSGSRLIRSYVPLAEMFGYATQLRSTTQGRGTYTMEFSHYDEVPDSIAKELMDV
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFDA_METKA
Sequence: MAEKKNEQEIQQELQRLIAEINRLQGQMEAINAQIDLIESSISELNRVEETLKGVKELEGDEEVLVPVGAQSFVRACVTDTERVIVGIGAGVAVERTIDEALESIDDQRQELEKARAEAQQKLQELAQELQEKQRKAQELAQQLEGAQRIAQQSGGG
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1388_STRP3
Sequence: MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVDWFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDKWNEKNQEVLSQFRAVDFVKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPYYQLLLLTFDRLNDMSQS
What are the official names of this protein?
UPF0398 protein SpyM3_1388.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: RF1_CHLL3
Sequence: MFDKLQSIKERHLDLERMLADPAAAGDQTRFRRLNKEYSDLKEIVQAYDRYASARQQLEESRHMQKAEEDPEMKAMAREEMLELEERIPGLEQELRILLLPKDEADSRNVIMEIRAGTGGEEAALFAADLMRMYQRYAERQGWRCEVLDYNESSGPGGFREVTLTISGHDVYGTLKYESGVHRVQRVPETETQGRIHTSAASVAVLPEAEEVDVEIRRDDLRFDTYRSGGKGGQNVNKVETAVRITHEPTGLVAACQEERSQLQNKERAMKMLMAKLYDIKLQEQQQERADMRRTMVASGDRSAKIRTYNYPQSRVTDHRIGFTSHGLPHFMQGEIGELIDALKMHDQTERLQEAARA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3PC2_ARATH
Sequence: MADKKIRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHHELKVKDDKTLLFGEKPVTVFGIRNPEDIPWGEAGADFVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPSLNGKLTGMSFRVPTVDVSVVDLTVRLEKAATYDEIKKAIKEESEGKMKGILGYTEDDVVSTDFVGDNRSSIFDAKAGIALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSKA
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).  Binds DNA in vitro (PubMed:22589465).  Together with DNA polymerase II subunit B3-1 (DPB3-1) and GAPC1, enhances heat tolerance and promotes the expression of heat-inducible genes (PubMed:32651385).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic, NAD-dependent glyceraldehydephosphate dehydrogenase C subunit 2.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Accumulates in the nucleus under heat stress.
Protein: SET2_COCIM
Sequence: MAGHDDEEARIETVKDAVTDMKLERQSSTESVAPNGILDTITPKDEPNGHLSSKPSTPSLKPPKSRSRSSNSLAKDEVPEEKVGGDITIKQEPGQPPKLARSASQKLPPRAAPLFTDLPDKTTEATSTFQLMEVCTYANKYLGYTEHAMDCDCAEEWDAATCRNTACGEDSDCINRATKMECFGDCGCGDSCQNQRFQRREYAKVSVIKTEKKGYGLRADCDLRPNEFIFEYIGEVINEPQFRRRMIQYDEEGIKHFYFMSLNKGEFVDATKKGNLGRFCNHSCNPNCYVDKWVVGEKLRMGIFAERYIKAGEELVFNYNVDRYGADPQPCYCGEPNCTGFIGGKTQTERATKLSHATIEALGIDDPDGWDTAVARRPRKKKAGEDDEEYVDSLQPKSLDENGVTKVMAALMQCKEKWIAVKLLGRIQRCEDERVRHRVVRMHGYQILNSQLNTWKDDFNVVLQILDILDKFPRLTRNKIIDSKIEGTVSPLQECDDERVAEKAKALLEIWSALEVGYRIPRMKRDPAAVNNTPTANHYERRETAKDDRKPNSSKSRSRSRSRSRSVDVTRNAPRGPAALTRGGGKGHMHSYRPGQRPFRRPFNPLPKGWFAAESNGRTYYYSATGETTWSRPTAPAVQPPPPPKRESKEKTLQDIIDGIMNAKENTPKAKDKSATPATPADAKIPEKKEHKEKWRSYSEEKQKKLYENTLFPHVKYIVDKFKHKLPKDDLKRYAKEVAKKLVNSDFKNNRVEDPTKISDKQVKQVKKYCKEYFDKAVAKHRAYEEKKAERKSKGSVKATTSATIDKAETTSTKAPPQFDGAAETGDEDSDVQLSDAEYEDGQEESSHHSGLKRKRTDDEDFENDHENGGVSPTKRQRSASLPIIPPPPPPMSPSNLVLDDGSREALKRQRTEGAEDDEYGDSTISSGKRQRSETPPPPPPPPPPADIPPENIESENENDKDQEELQDYDVQEANWGKEDNIAIQSPSHSPFPAQSISNHSNTARETDSHS
What is the function of this protein?
Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3.  Involved in transcription elongation as well as in transcription repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-36 specific, SET domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SPEB_ECOHS
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMSVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: MIAB_MYCVP
Sequence: MTSTVTQQASGPSPDRSARTFEVRTYGCQMNVHDSERLAGLLEGAGYRRAGEGADADIVVFNTCAVRENADNKLYGNLSHLAPRKQSDPDMQIAVGGCLAQKDRDSVLRKAPWVDVVFGTHNIGSLPALLDRARHNRVAQVEIAEALQEFPSALPASRESSYAAWVSISVGCNNTCTFCIVPALRGREVDRRPGDVLAEVQSLVDQGVLEITLLGQNVNAYGVSFADPTEPRDRGAFAKLLRACGRIDGLERVRFTSPHPAEFTDDVIEAMAETPNVCPTLHMPLQSGSDRILRAMRRSYRAERYLGIIDRVRAAIPHAAITTDLIVGFPGETEEDFQATLDVVAASRFSSAFTFQYSKRPGTPAAELADQVPKAVVSERYQRLIELQERISLEENTAQIGRRVELLVATGEGRKDAATARMSGRARDGRLVHFAPGAVGSEVRPGDVVVTTVTGAAPHHLIADAGLIEHRRTRAGDAHAAGQKPRTGVGLGMPAVGAPDPLPATTGCAR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.