PharMolix/UniProtQA huggingface dataset:
Protein: YAE3_SCHPO
Sequence: MESLESVDASSGSVGSYMSKSVRKHWWSRKGYHPTGSSKNGSRLKISSDENFQDELVVLDDAFLCNVPLELPSTSNAQKTAAESFSKLSPQDQLLSLQLNNVQESVFQQSTFNLPDALLDPGPASKEKQAVLSIGRPSWLPPKSKEEEKKHMREFEQIKKSAMRYDRQKQKEKIKMVEQKNKRNLYLVNVWEREILRNWPDALKSSRYAGIWRQGIPSRVRGRVWEKAIGNNLKLDYQSFFNARANAQKREAAEKAEQMNNANQFREDVCALELDLQSTMPHYSLFHTEGPLRRDLIGLLRAYSYYRFDTSYIPGTSFIGALLLLNMNLTSAFNCLANLLDKPFLQAVYTQDTSSLKSFYQTFLDTLKKNEPELATHLLIKLELVPDDFVYPLLRKLFIPMVSPEIASRILDCYVFEEDSFFIQLLMAVFKLLKPKLLVDDSRLVLSALLFENWDLGPEDEFMHFVYDISLS
What are the official names of this protein?
TBC domain-containing protein C23D3.03c.
Protein: TPIS_MAIZE
Sequence: MGRKFFVGGNWKCNGTTDQVEKIVKTLNEGQVPPSDVVEVVVSPPYVFLPVVKSQLRQEFHVAAQNCWVKKGGAFTGEVSAEMLVNLGVPWVILGHSERRALLGESNEFVGDKVAYALSQGLKVIACVGETLEQREAGSTMDVVAAQTKAIAEKIKDWSNVVVAYEPVWAIGTGKVATPAQAQEVHASLRDWLKTNASPEVAESTRIIYGGSVTAANCKELAAQPDVDGFLVGGASLKPEFIDIINAATVKSA
What are the official names of this protein?
Triosephosphate isomerase, cytosolic, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_CAMJR
Sequence: MLLGVNIDHIAVLRQARMVNDPDLLEAAFIVARHGDQITLHVREDRRHAQDFDLENIIKFCKSPVNLECALNDEILNLALKLKPHRVTLVPEKREELTTEGGLCLNHAKLKQSIEKLHNANIEVSLFINPSLEDIEKSKILKAQFIELHTGHYANLHNALFSNISHTAFALKELNQDKKTLQAQFEKELQNLELCAKKGLELGLKVAAGHGLNYKNVKPVVKIKEICELNIGQSIVARSVFTGLQNAILEMKELIKR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOML_HIPHI
Sequence: MNMMTVKQGVWAALLWPYLLAASIPLDCKDEQGSFSACPSISQEKLLDRVIQHAELIYRVSEESCSMFEEMFVPFPLRLQRNQAGYACITKALPIPSSKSEIQQISDTWLLHSVLLLVQSWIDPLVYLQTTLDRYDNASEMLLNKTKWVSDKLISLEQGVVVLIRKMLDEGMLTATYNEQGLFQYDVLPDMLESVMRDYTLLSCFKKDAHKMEIFLKLLKCRQTDKYNCP
What are the official names of this protein?
Somatolactin, SL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NOP9_ASPOR
Sequence: MPRENQKRGRRAAEKAEKDAAKRKREEVPEDSLPKRLKPSTDESTEINQGADYIPFDENYNENYDGNYDENQADAPAGDMPFYGLLDPEEQEYFSRANEVLELNQFQDAEERRIFIDSVYKEANGKELKIACSQGCSRLMEKLISMSDMRQIHRLFNKFIGHFMNLVQHRFASHCCETLFINAAPGVTQKVSKSKSDKMDVDEEEGEEPEPELSLAEMFIKVVEELEGNWGYLLTERFASHTIRVLLLVLAGEPVDVSANDSVVASRKKEKLGLPQGETQDGDVSAQKRSVPDVFEATLKKIMKDIVSVLDDTYLRALATHPVGNPVLQVLVSLELSHFGKSSAKDPNSITRRLIPDESFEEGSETTTFVRGLLYDPVGSRLLETIVRCMPGKAFKGLYKNFIRDQITSLARNITAGYVVLRVLERLGKDDLQNALERIVPQVPSLLERSRMVVPKVLIERCLVRGVDTAPLARALEEAYDKDPARRLEQILRLESTTQEDLEESEQKPKGANAAPSQSSTGEKLHGSLLAQTMLTAPGPISGLIYSSLLAQSSESLVKIAKDPTASRVLQQALTVPTSSAQFRRQFAPRFTSHLKELALDSSGSHVVDALWPATKDIFFIKERMAQELTQHEMALRDSFVGRAVWRNWAMDLYKRRRGEWAMKAKGIDNNNGSGERPKSRIELARAKFAAKAEEDAKKGAQKGVTA
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein nop9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: UBIC_METFK
Sequence: MRDRWLKRAVGARHYRPWLTERGSLTRRLQQHSRQFAVQPLHLARKKPPLAEAQLLQVLPRQHTLQRDVILRCDGEAVVFAHSLLPQQAMRGTWRGLGRLGSHSLGSALFADPRMCRGALQYKKLSPQHFLYRLAVAHIPAMRGPIWARRSVFRLGRKAVLVSELFLPSVLKLPLINK
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_PSYWF
Sequence: MKALIQRVSAASVRVDNQIVGQIEQGILAYIGLGPEDTLKSAQKMIDKILGYRIFDNDAGKLDKNVQQVAGGLLLVSQFTLMAKTDKGRRPDFGGAMPPAQASELFKQMIDYAKQQHDKVATGEFGANMLVQADNDGPLNFILEIS
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHB_ECO27
Sequence: MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAENTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.  Has a clear preference for cytidine over uridine.  Strictly specific for ribonucleosides.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihB, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihB subfamily.
Protein: CTRB_NEIMB
Sequence: MSEQLPVAVATETKAERKKPKKKSWIKKLSPLFWVTVIIPTVISLVYFGFFASDRFTSQSSFVVRSPKSQSSLNGLGAILQGTGFARAQDDIYTVGEYMRSRSSLDELRKILPVREFYETKGDAFSRFNGFGFRGEEEAFYQYYKNQVMINFDTVSGISTLNVTSFDALESKKINEALLKQGEALINQLNDRARADTVRYAEEVVKTAAERVKEASQNLTDYRIANGVFDLKAQSEVQMGLVSKLQDELIVIQTQLDQVKAVTPENPQIPGLQAREQSLRKEIDQQLRAISGGGHSSLSNQAAEYQRVYLENQLAEQQLAAAMTSLESAKVEADRQQLYLEVISQPSLPDLAHEPKRLYNIVATLIIGLMVYGILSLLTASIREHKN
What is the function of this protein?
May form an ATP-driven capsule polysaccharide export apparatus, in association with the CtrC and CtrD proteins.
What are the official names of this protein?
Capsule polysaccharide export inner-membrane protein CtrB.
What is the protein family that this protein belongs to?
Belongs to the BexC/CtrB/KpsE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MAPC1_ARATH
Sequence: MEAEKSKQNPGKKPVEATMEHVLVALRETKEKREIRIQKLFEFFDNSKLGFLDDTQIEKGLSSLSIPPKYRYASDFLKVCDSNRDGRVDYQEFRRYMDAKELELYKIFQAIDIEHNGDICPAELWEALDKAGIKIKDEELASFMEHVDKDNNGIITFEEWRDFLLLNPHEATIENIYHHWERVCLIDIGEQAVIPDGISAHAQRSKLLLAGGIAGAVSRTATAPLDRLKVALQVQRTNLGVVPTIKKIWREDKLLGFFRGNGLNVAKVAPESAIKFAAYEMLKPIIGGADGDIGTSGRLLAGGLAGAVAQTAIYPMDLVKTRLQTFVSEVGTPKLWKLTKDIWIQEGPRAFYRGLCPSLIGIIPYAGIDLAAYETLKDLSRAHFLHDTAEPGPLIQLGCGMTSGALGASCVYPLQVIRTRMQADSSKTSMGQEFLKTLRGEGLKGFYRGIFPNFFKVIPSASISYLVYEAMKKNLALD
What is the function of this protein?
Calcium-dependent mitochondrial carrier protein that catalyzes the import of ATP co-transported with metal divalent cations across the mitochondrial inner membrane in exchange for phosphate (Pi) (PubMed:22062157, PubMed:28695448, PubMed:26140942, PubMed:26444389).  Can transport phosphate, AMP, ADP, ATP, adenosine 5'-phosphosulfate and, to a lesser extent, other nucleotides (PubMed:26140942, PubMed:26444389).  Binds calcium ions Ca(2+) (PubMed:22062157).  Mediates also calcium uptake (By similarity).
What are the official names of this protein?
Calcium-dependent mitochondrial ATP-magnesium/phosphate carrier protein 1, AtAPC1, Mitochondrial ATP-Mg/Pi carrier protein 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CCME_LEGPH
Sequence: MTPVRRRKLFILLFALSVLSAAAALVLYALRQNISLFYTPTQIVAGEAPAKHHIRVGGMVEANSIVRAKKGLDVQFKITDFENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHATQVLAKHDANYMPPQVKSALADKVKQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: BIOF_MYCUA
Sequence: MGAPTQIPIETSPLAWLDAVERQRRDAGLRRSLRPRPPVGTELDLASNDYLGLSQHPDVIEGGVQALRIWGAGATGSRLVTGDTELHQQLEAELAEYVGAAAGLLFSSGYTANLGAVVGLSGPGSLLVSDAYSHASLVDACRLSRARVVVTPHRDVAAVDAALASRDEQRAMVITDSVFSADGTLAPLRELLAACRRHRALLVIDEAHGLGVRGGGRGLLHELGLAGAPDVVLTTTLSKALGSQGGAVLGPAAVRAHLIDAARPFIFDTGLAPGAVGAARAALGVLKAEQWRPGAVLQNARELADICDVPETPQSAVVSVLLGDPEVALAAAAACLDAGVKVGCFRPPTVPAGTSRLRLTARASLSPDEMELARRVLTDVLLGPAAARR
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: CITE_ECOLI
Sequence: MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLEDSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIREE
What is the function of this protein?
Represents a citryl-ACP lyase.
What are the official names of this protein?
Citrate lyase subunit beta, Citrase beta chain, Citrate (pro-3S)-lyase subunit beta, Citryl-CoA lyase subunit.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABA4_BOTFB
Sequence: MSSQPFTNKVIALTGSASGIGLETAKLLASRGARLSLADIQEDKLKELQAQLESEYYVDVITTKVDVRKFGEVEAWINKTIDNFGKLDGSANLAGVAPESIGLKGIVEQDLDEWEFVLGVNLTGTMNSLKAQLKVMANNGSIVNASSIRGLTGAAKNASYSSAKHGIIGLTRTAAKEVGGKGIRVNAICPGRISTPMLKTAENSIGLHLQPGSANYPPIALGRDGEAKEVAQLVAFLLSDESTYISGADISIDGGWRC
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of abscisic acid (ABA), a phytohormone that acts antagonistically toward salicylic acid (SA), jasmonic acid (JA) and ethylene (ETH) signaling, to impede plant defense responses (PubMed:15240257, PubMed:16820452).  The first step of the pathway catalyzes the reaction from farnesyl diphosphate to alpha-ionylideneethane performed by the alpha-ionylideneethane synthase aba3 via a three-step reaction mechanism involving 2 neutral intermediates, beta-farnesene and allofarnesene (PubMed:30226766).  The cytochrome P450 monooxygenase aba1 might then be involved in the conversion of alpha-ionylideneethane to alpha-ionylideneacetic acid (Probable).  Alpha-ionylideneacetic acid is further converted to abscisic acid in 2 steps involving the cytochrome P450 monooxygenase aba2 and the short-chain dehydrogenase/reductase aba4, via the intermediates 1'-deoxy-ABA or 1',4'-trans-diol-ABA, depending on the order of action of these 2 enzymes (Probable).  Aba2 is responsible for the hydroxylation of carbon atom C-1' and aba4 might be involved in the oxidation of the C-4' carbon atom (PubMed:16820452).
What are the official names of this protein?
Short-chain dehydrogenase/reductase aba4, Abscisic acid biosynthesis cluster protein 4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: CLPP_XANOP
Sequence: MSIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEADNPEKDISIYINSPGGVVTAGMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEILAKHTGQSLETIARDTERDNFKSAVDAQAYGLVDQVLERRPEESIQPS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4940_BURM1
Sequence: MTDAPRSPDALSPDRVTTAFDLPGHTTVRALGVAQGIVVRSRSIVGTFGASLQTLFGGNITLYTSLCEKARQHAFDKMLDDARRLGANAVVAMRYDSTEIGSGVTEVICYGTAVQVAPDAGR
What are the official names of this protein?
UPF0145 protein Bmul_3577/BMULJ_04940.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: OOEP_HUMAN
Sequence: MVDDAGAAESQRGKQTPAHSLEQLRRLPLPPPQIRIRPWWFPVQELRDPLVFYLEAWLADELFGPDRAIIPEMEWTSQALLTVDIVDSGNLVEITVFGRPRVQNRVKSMLLCLAWFHREHRARAEKMKHLEKNLKAHASDPHSPQDPVA
What is the function of this protein?
As part of the OOEP-KHDC3L scaffold, recruits BLM and TRIM25 to DNA replication forks, thereby promoting the ubiquitination of BLM by TRIM25, enhancing BLM retainment at replication forks and therefore promoting stalled replication fork restart (By similarity).  Positively regulates the homologous recombination-mediated DNA double-strand break (DSB) repair pathway by regulating ATM activation and RAD51 recruitment to DSBs in oocytes (By similarity).  Thereby contributes to oocyte survival and the resumption and completion of meiosis (By similarity).  As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity).  Required for the formation of F-actin cytoplasmic lattices in oocytes which in turn are responsible for symmetric division of zygotes via the regulation of mitotic spindle formation and positioning (By similarity).
What are the official names of this protein?
Oocyte-expressed protein homolog, KH homology domain-containing protein 2, Oocyte- and embryo-specific protein 19, hOEP19.
What is the protein family that this protein belongs to?
Belongs to the KHDC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL16_MYCPA
Sequence: MLIPRKVKHRKQHHPRQRGIASGGTAVNFGDYGIQALEHAYVTNRQIESARIAINRHIKRGGKVWINVFPDRPLTKKPAETRMGSGKGSPEWWVVNVKPGRVLFELSYPNEQTARAALTRAIHKLPIKARIVTREDQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TRM1_SULTO
Sequence: MNLIEIREGKASLLIPNPKDYEKEGRYDPSWSPVFYNPKMRLNRDISVLALSVIKPKSVVDALSASGVRGIRYYTEIGGIEKLILNDKNPIATELIKKNAEKNYVNARITTKDANSLLYEIKADFVDIDPFGSPAPFILSAINATINKGYVAFTATDLSALECSSKFSARRKYDLICERLSFSKELGIRGLIAKVIREGAIIEKAAYPIFSFYFDYYYRVFFRIENGAKKVDKLLEKQGYYYECSKCGYREVDYYAERKICPRCGIEMRRYGPAWTGELWNREFLLSMKENLKNFTYFDTFMQVNKLLNILVEESKYVSPYFRLDFIASLIKRNIPKREKMLECLKEASITHFDYRGIKTNKEIDEIVNCIKIN
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: DDX5_HUMAN
Sequence: MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGYSQ
What is the function of this protein?
Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner.  Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10.  The rate of ATP hydrolysis is highly stimulated by single-stranded RNA.  Involved in transcriptional regulation; the function is independent of the RNA helicase activity.  Transcriptional coactivator for androgen receptor AR but probably not ESR1.  Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation.  Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis.  Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation.  Acts as transcriptional repressor in a promoter-specific manner; the function probably involves association with histone deacetylases, such as HDAC1.  As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX5, DEAD box protein 5, RNA helicase p68.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus speckle. Cytoplasm. Note=During the G0 phase, predominantly located in the nucleus. Cytoplasmic levels increase during the G1/S phase. During the M phase, located at the vicinity of the condensed chromosomes. At G1, localizes in the cytoplasm.
Protein: BAMA_BUCAP
Sequence: MLIKTIFIIFLMFFSVNVFSKNVWIIENIQFKGLKYFSKDEVLKNIFFNIGSNISENDIKHSIKSLFQTGKFETIKIVHSGKTIIFEIKERPIISNITFSGNKIIKDSILKKYLTELGIKEGNFFNPFLNTVFVKNLKEFYSNVGRYNSDIKIFKKISSNNKIDLQIFIHESNLVEINHIKIIGNNHFPRDKILSLFKLKDCKSWWNFLEKRFYYSQQLEEDLKNLSNFYLNQGYYYFNIHRKKVRFLKDKNKVNITVYISEGKKYKISNFFLNGNLLQYYQSIKNFINIHNNEFYNKEKITLIVKKIQRFLSEKGYIDPKIIIYPQINFKEKKIILNFNIDIQKRYFVNKINFRGNELTQDIVLRREMKQIEGEWFNLKLIELGIKSLEKLKFLSDITVQKEILFNKENGVDITYTLKEQPTGTLNFGLGYGRDSGLSFNASISQDNLFGSGNSLKASIIKNDNQKYADISIMHPYFIDDGTNLDTRIFYNDFKYNINSFYNIVKTTSGFESDLSFLINAFNRVNIGFGYTHNGLLNKEEKFFSKNGNKSSDKFLKTSLVDDFTLNYSLTHDTLKYFYFPISGNQTYISGKNTIPGSDNKFYKFLFDSEQYIPLEEEKKFIFLTHIRAGIGNSLNKEKLPFYENFHAIDSNNIRGFRANTIGPKKIYINSNLEECLGYNKKSIFCESVDSIGGNAMIISNLELITPIPLIKTEYSKFLRSSFFLDAGNIWDTRWDKEQNIHFSQFPDYTILNNIQASIGISLQWFSPIGPLVFSYAYPIYKNKNNQLEAFQFNFGKNW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RISA_AQUAE
Sequence: MFTGLVEDLGKVKNLTLSSKGAKLSVETKLEDVKLGDSVSVNGACLTVVDIKSSTLTFDVSPETLKRTNLGKLKTGDYVNLERALRVGERLGGHIVQGHVDFTAPVKSFNFLGEHYELVIEIPEEWSIYVVEKGSIALDGISLTVNYVKENKVFINIIPHTYKSTNLQFKKVGDLLNVETDILGKYVINYLNKLKKKEDIFKEFLKW
What is the function of this protein?
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
What are the official names of this protein?
Riboflavin synthase, RS.
Protein: AROB_FRATM
Sequence: MISKLSVNPTFSPSYNIIVDSVLDFSHILEYVTNKQVLVVTNTTVAKLYLTKFLPALVDDLDVRTCILEDGEQYKSQQSLDKILSTLLENHFTRNSTVLVALGGGVIGDITGFAAAIYQRGIDFIQIPTTLLSQVDSSVGGKTAINHQLGKNMIGAFYQPKVVYTSIEFYKTLPQREYIAGMAEVVKYAFISKDFYLWLDSNRDKILAKDSVTLIEMVKRSCQIKAQVVAMDEKELTGARAILNFGHTFGHAIEKCQNYRGLKHGEAVGVGMAQAIDFSHYLGLISQQQAKDFKDFIVSFGISIDFPNDICQKEFLEAMLLDKKNSNKELKFILIENIGSLSLQKQSKNELEQFLDISR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QORL1_MOUSE
Sequence: MKGLYFQQSSTNEEVTFVFQEKENVPVTEDNFVRVQVKACALSHINTKLLAEMKMEKDFFPVGREVSGIVLEVGRKVTFFQPDDEVVGILPLDSEDPGLCEVIRVHEHYLVHKPEKVSWTEAAGVIRDGVRACTALYYLSQLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTAHSLEDKQHLERLRPSIARVIDVSNGKVHVAESCLEETGGLGVDIVIDAGVRLYSKDDEPAVKLHLPHKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFLKGATVAFLNDEVWNLSNAQQGKYLCILKDVMEKLSAGVFRPLLDEPIPLYEAKVSMEVVQKNQERKKQVVQF
What are the official names of this protein?
Quinone oxidoreductase-like protein 1, Quinone oxidoreductase homolog 1, QOH-1, Zeta-crystallin homolog.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: MTFA_KLEP7
Sequence: MFKWPWKADDESGNAEMPWEQALAIPVLAHLSSTEQHKLTQMAARFLQQKRLVALQGLELTPLHQARIAMLFCLPVLELGIEWLDGFHEVLIYPAPFIVDDEWEDDIGLVHNQRVVQSGQSWQQGPVVLNWLDIQDSFDASGFNLVVHEVAHKLDTRNGDRASGVPLIPLREVAGWEHDLHAAMNNIQDEIDLVGESAASIDAYAATDPAECFAVLSEYFFSAPELFAPRFPALWQRFCHFYRQDPLARRRENGLQDEGDRRIVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBSN_HUMAN
Sequence: MHLARLVGSCSLLLLLGALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQVGKEADKLIHHGVHHGANQAGSEAGKFGQGVDNAAGQAGNEAGRFGQGVHHAAGQAGNEAGRFGQGVHHAAGQAGNEAGRFGQGAHHGLSEGWKETEKFGQGIHHAAGQVGKEAEKFGQGAHHAAGQAGNEAGRFGQGVHHGLSEGWKETEKFGQGVHHTAGQVGKEAEKFGQGAHHAAGQAGNEAGRFGQGAHHAAGQAGNEAGRFGQGVHHGLSEGWKETEKFGQGVHHAASQFGKETEKLGHGVHHGVNEAWKEAEKFGQGVHHAASQVGKEEDRVVQGLHHGVSQAGREAGQFGHDIHHTAGQAGKEGDIAVHGVQPGVHEAGKEAGQFGQGVHHTLEQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGASVNTPFINLPALWRSVANIMP
What are the official names of this protein?
Suprabasin.
What are the subcellular locations of this protein?
Secreted.