PharMolix/UniProtQA huggingface dataset:
Protein: RRAA_ECO7I
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_LEPBP
Sequence: MKTDIHPKYVAAKIKCACGTVIETRSTSGDISVEICSNCHPFFTGKSKLVDTTGRVDKFKKKYKMK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ABC3G_HUMAN
Sequence: MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
What is the function of this protein?
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms.  Exhibits potent antiviral activity against Vif-deficient HIV-1.  After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA.  The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells.  Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA.  Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs), hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV).  May inhibit the mobility of LTR and non-LTR retrotransposons.
What are the official names of this protein?
DNA dC->dU-editing enzyme APOBEC-3G, APOBEC-related cytidine deaminase, APOBEC-related protein, ARCD, APOBEC-related protein 9, ARP-9, CEM-15, CEM15, Deoxycytidine deaminase, A3G.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Mainly cytoplasmic. Small amount are found in the nucleus. During HIV-1 infection, virion-encapsidated in absence of HIV-1 Vif.
Protein: ZNHI2_MOUSE
Sequence: MEPAGLCGFCPAGEALPARYTCPRCNAPYCSLRCYRAHGACAEDFYRDQVLRELRGRSASPSRLAGALRRLREQREAEDEPEEAGLGPGARPGGLSGLWERLTPAEKAAFERLLSRGEAGRLLPPWRPWWWGRGTGPRLLEELDHAANRDLAEPEPAPARTALQSGDDAAAAEPFAEDSCAARPLALPARIPALASLSRSPASPLVRFQLPNVLFAYAHTLALYHGGDDDALLSDFCATLLDVSGALGAQQVFGSTEEALQAAAHVLEAGEHPPGPLGTRGAMQEVARILLGEGPVNQKGYTLTALGHLAQTLGRARKQAVIGGERDRLYRARKKCQFLLAWTNENEAALTPLALDCARAHRAHAVTAEEMATLTGELERLWGGPVPPTPRTLIEELPG
What is the function of this protein?
May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP) (By similarity).  Required for the interaction of R2TP complex subunit RPAP3 and prefoldin-like subunit URI1 with U5 snRNP proteins EFTUD2 and PRPF8 (By similarity).  May play a role in regulating the composition of the U5 snRNP complex (By similarity).
What are the official names of this protein?
Zinc finger HIT domain-containing protein 2, Protein FON.
Protein: RUVB_LEPCP
Sequence: MAIQTDSFAAAPAPSSGSTRRLISAAPTSPNEEAMERALRPKLLQEYVGQAKAREQLEIFIGAARKRSEALDHVLLFGPPGLGKTTLSHIIAAELGVNLRQTSGPVLEKPKDLAAILTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPEELVRIVTRSAGLLNVPIDAEGALELACRSRGTPRIANRLLRRVRDYAEVKSDGRIVKRIAELALTMLDVDPRGFDVMDRKLLEAVIHRFDGGPVGLDNVAAAIGEDAGTIEDVIEPYLIQQGFLQRTPRGRIATLAAYRHLGVTPPRGGAGPVGSDLFEG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: AT8OS_HUMAN
Sequence: MPCPGAPCCSLVATGSRVPFSGLKEEEEEDGEDDEEEEEEGFFQKVLTPLLSWLLSRRLWLGPQCSKLPLPSCCRQPPPAGPPVEGDGWLKSFQRSRRMCFTSKSFRPEPDMLYAQKAKGWQLTQDSGGWEVQDQCTRIWSKENLLALNTHSRRQKGKRENKVCVSTWQKSRGDRTYSSMATTPSMTKILEGCMYRKLKC
What are the official names of this protein?
Putative protein ATXN8OS, ATXN8 opposite strand, Spinocerebellar ataxia 8, kelch-like 1 antisense.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_MYCA1
Sequence: MSDIPPDLHYTAEHEWVRRSGDDTVRVGITDFAQSALGDVVFVQLPEVGAQLTAGESFGEVESTKSVSDLYAPVSGTVTAVNTDLEGSPQLVNSDPYGAGWLLDVQVSDAAALESAITALLDAEAYRGTLTE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: AROC_DEHMB
Sequence: MSNSLGKLFQITSFGESHGDCVGVVIDGVPAGLAINVDEIQIEVDKRKSGAKAHTTPRREDDRIEIFSGIFNNFTTGAPICLVIWNKNIDSSEYERTRSKIRPGHADFTGFMKYGGFNDYRGGGRFSGRITAGHVMAGAIARKLISTIGIEVIGYTAELGGITAKLPKHKDIRQNISQSDVNCPDLAASKQMVALIQQAAEEGDSLGGVVECIGLNLPVGLGEPVFDTLEGELAKAIFAIPAVKGVEFGAGFGASRLRGSKNNDPFNIQSDQIRTTSNNCGGILGGISDGMPLHIRVAVKPTPSISLSQPTVNLDTMTNTSLEIRGRHDTCIVPRAVSVVEAMTCIVLADLALRAGIIPRVIKQ
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CYB_CEPZE
Sequence: MTNIRKTHPLLKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTYMETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFIFPFIIAALAMVHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGALLLILALMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILILMPLLHTSKQRSMMFRPISQCLFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPVASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DAG1_CANLF
Sequence: MRMSAGLSLLLPLWGRTFLLLLSVAMAQSHWPSEAGRDWENQLEASMHSVLSDLHEAVPTVVGIPDGIAVVGRSFRVTIPMDLIASNGELVKVSAVGKEVLPSWLHWDPQSHTLEGLPLDTDKGVHYISVSATRLGANGSHVPQTSSVFSIEVYPEDHSEPQSVRAASPDPAEVVSSACAADEPVTVLTVILDADLTKMTPKQRIDLLHRMRSFSEVELHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCSLNQNNVPDIHGVEAPAREGAMSAQLGYPVVGWHIANKKPPIPKRIRRQIHATPTPVTAIGPPTTAIQEPPSRIVPTPTSPAIAPPTETMAPPVRDPVPGKPTVTIRTRGAIIQTPTLGPIQPTRVSEAGTTVPGQIRPTMTIPGYVEPTAVATPPTTTTKKPRVSTPKPATPSTDSSTTTTRRPTKKPRTPRPVPRVTTKAPITRLETASPPTRIRTTTSGVPRGGEPNQRPELKNHIDRVDAWVGTYFEVKIPSDTFYDHEDTTTDKLKLTLKLREQQLVGEKSWVQFNSNSQLMYGLPDSSHVGKHEYFMHATDKGGLSAVDAFEIHVHKRPQGDRAPARFKAKFMGDPVPVVNDIHKKISLVKKLAFAFGDRNCSTITLQNITRGSILVEWTNNTLPLEPCPKEQIMALSQRIAEDNGKPRAAFSNALEPDFQASSIAVTGSGSCRHLQFIPVAPPRRVPSEVPSTDVPDRDPEKSSEDDVYLHTVIPAVVVAAILLIAGIIAMICYRKKRKGKLTLEDQATFIKKGVPIIFADELDDSKPPPSSSMPLILQEEKAPLPPPEYPNQSVPETTPLNQDTVGEYTPLREEDPNAPPYQPPPPFTAPMEGKGSRPKNMTPYRSPPPYVPP
What is the function of this protein?
Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton.  Acts as a cell adhesion receptor in both muscle and non-muscle tissues.  Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton.  Also functions in cell adhesion-mediated signaling and implicated in cell polarity (By similarity).
What are the official names of this protein?
Dystroglycan 1, Dystroglycan, Dystrophin-associated glycoprotein 1.
What are the subcellular locations of this protein?
[Alpha-dystroglycan]: Secreted, extracellular space. SUBCELLULAR LOCATION: [Beta-dystroglycan]: Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Nucleus, nucleoplasm. Cell membrane, sarcolemma. Postsynaptic cell membrane. Note=The monomeric form translocates to the nucleus via the action of importins and depends on RAN. Nuclear transport is inhibited by Tyr-892 phosphorylation. In skeletal muscle, this phosphorylated form locates to a vesicular internal membrane compartment. In muscle cells, sarcolemma localization requires the presence of ANK2, while localization to costameres requires the presence of ANK3. Localizes to neuromuscular junctions (NMJs) in the presence of ANK2 (By similarity). In peripheral nerves, localizes to the Schwann cell membrane. Colocalizes with ERM proteins in Schwann-cell microvilli (By similarity).
Protein: RL15_EHRRG
Sequence: MDVVMKLNNIFSGLPKKKKSKVLGRGIGCGKGKTSGRGHKGQKARSGVSINGFEGGQQSIFTRLPKRGFNSLPKNKYSIINVSLIQRLIDSGKIDNVSAITKEVLYNLGVISSVKQKIKILGDGKLNTTVCIEYDFISKSAKSQVTLLNSLSDSESK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PSTS2_STRR6
Sequence: MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISRENGSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSLTKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVVTDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNGSSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAELADVFSGKLTTWDKIK
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS 2, PBP 2.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y2087_DICDI
Sequence: MIFAIDLIKSNCKREILKIKKIKINYLFYGNCRYLINMINLKSSTTRILQPLDSVVISHDS
What are the official names of this protein?
Putative uncharacterized protein DDB_G0268290.
Protein: NAMB1_TRIDC
Sequence: MGSSDSSSGSAQKATRYHHQHQPPPPQRGSAPELPPGFRFHPTDEELVVHYLKKKADKAPLPVNIIAEVDLYKFDPWELPEKATIGEQEWYFFSPRDRKYPNGARPNRAATSGYWKATGTDKPILASGTGCGLVREKLGVKKALVFYRGKPPKGLKTNWIMHEYRLTDASGSTTATNRPPPVTGGSRAAASLRLDDWVLCRIYKKINKAAAGDQQRNTECEDSVEDAVTAYPLYATAGMTGAGAHGSNYASPSLLHHQDSHFLDGLFTADDAGLSAGATSLSHLAAAARASPAPTKQFLAPSSSTPFNWLDASPVGILPQARNFPGFNRSRNVGNMSLSSTADMAGAVDNGGGNAVNAMSTYLPVQDGTYHQQHVILGAPLVPEAAAATSGFQHPVQISGVNWNP
What is the function of this protein?
Transcription factor of the NAC family associated with the grain protein content (GPC).  Accelerates senescence and increases nutrient remobilization from leaves to developing grains.  The tetraploid cultivated wheat (T. durum) and the hexaploid wheat (T. aestivum) carry a one bp insertion generating a non-functional allele of this gene.  They have a delayed senescence and a lower grain protein, zinc and iron content (PubMed:17124321).
What are the official names of this protein?
NAC transcription factor NAM-B1, TtNAM-B1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HNF1A_MOUSE
Sequence: MVSKLSQLQTELLAALLESGLSKEALIQALGEPGPYLMVGEGPLDKGESCGGSRGDLTELPNGLGETRGSEDDTDDDGEDFAPPILKELENLSPEEAAHQKAVVESLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHAGQGGLIEEPTGDELPTKKGRRNRFKWGPASQQILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEVRVYNWFANRRKEEAFRHKLAMDTYNGPPPGPGPGPALPAHSSPGLPTTTLSPSKVHGVRYGQSATSEAAEVPSSSGGPLVTVSAALHQVSPTGLEPSSLLSTEAKLVSATGGPLPPVSTLTALHSLEQTSPGLNQQPQNLIMASLPGVMTIGPGEPASLGPTFTNTGASTLVIGLASTQAQSVPVINSMGSSLTTLQPVQFSQPLHPSYQQPLMPPVQSHVAQSPFMATMAQLQSPHALYSHKPEVAQYTHTSLLPQTMLITDTNLSTLASLTPTKQVFTSDTEASSEPGLHEPPSPATTIHIPSQDPSNIQHLQPAHRLSTSPTVSSSSLVLYQSSDSNGHSHLLPSNHSVIETFISTQMASSSQ
What is the function of this protein?
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (PubMed:19289501).  Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (PubMed:10966642).  Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (PubMed:30555544).
What are the official names of this protein?
Hepatocyte nuclear factor 1-alpha, HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1.
What is the protein family that this protein belongs to?
Belongs to the HNF1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPD_VIBCH
Sequence: MAYFALGLATATKNRDGKIIEAFFPTPILAPSDALVAALAPIAGYQEGNQALDITAAQSAQLAAVFAAHQQAASAAFADKAANAKQPLVLVILASDDKPQSVAEGYLKLQLISHRLVKPHGTVLDGIFGLLHNIAWTNEGPIDLPELAERQIEARLAGRVLTVDCVDKFPKMVDYVVPAGIRIADTSRVRLGAHVGEGTTVMHEGFINFNAGTTGVSMVEGRISAGVVVGNGSDIGGGASIMGTLSGGGKVVVSIGENSLLGANAGLGFPLGDRCTVESGLYVTAGTKVRTLDKDGNQVDIVKARDLAGVSDLLFRRNSLTGQIECLANKSAVELNSELHKNN
What is the function of this protein?
Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QSOX1_PONAB
Sequence: MGRCNRGSGPPSSLLLLLLLLLWLLAVPGASAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPARLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKFADRSKIYMADLESALHYILRIEVGRFPVLEGQCLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAARQNIDRSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVRSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNIILDFAAAGSAAQREAQNVAAAPELAMGALELESRNSTVDLGKPEMMKSSTNTTPDVPAERPEASRPPKLRPGLGAAPGQEPPEHMAELQTNEREQPRGQWHLSKRDTGAALLAESRAEKNHLWGPSEVRRVGRSSKQLVDIPEGQLEAQAGRGRGQWLQVLGGGFSYLDISLCVGLYSLSFMGLLAMYAYFRAKIRALKGHAGHPAA
What is the function of this protein?
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.  Plays a role in disulfide bond formation in a variety of extracellular proteins.  In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration.
What are the official names of this protein?
Sulfhydryl oxidase 1, Quiescin Q6.
What is the protein family that this protein belongs to?
Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein. Secreted. Note=A small proportion is secreted, probably via a proteolytic cleavage that removes the membrane anchor.
Protein: MOAA_PECAS
Sequence: MVSQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYQANGTNPHRFLSLDEIRRVSRAFAELGTEKVRLTGGEPSLRRDFVDIIAAIRENPAIRTLAVTTNGYRLARDVAQWRDAGLTALNVSVDSLDARQFHAITGQDKFRQVMDGIDAAFDCGFAKVKVNTVLMRDVNAGSLQTFLDWIKHRPIQLRFIELMETGEGGELFRRHHVSGEVIRQQLLQQGWQQQQRARSDGPAQVFCHPDYEGEIGLIMPYEKDFCLSCNRLRVSAIGNLHLCLFGEQGIPLRDLLADDRHLNDLKMRISGGLSTKKQTHFLHEGNSGITQNLSFIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RS5_NATPD
Sequence: MSNGWEPRTRLGRKVADGEITSMQDALQSGLPLKEPELVDQLLPGLEDEVLDINMVQRMTDSGRRVKFRCVVVIGNRDGYVGYAQGRDDQVGGAIQKAIDVAKLNIIDVPLGSGSWEDRPGGRNSLMRRTTGKAGSVEVELKPAPRGLGLAAAPTVRHVLELAGVEDAWTKCHGNTRTTLNLAKATYNALRNASESRTPEHTRQVRQEAQE
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RAB36_MOUSE
Sequence: MRSSWTPLGPPVSQDRIITSFPKWYTPDACLQLKEHFHSRVSTACQHRNTGTAGLRLSKVVVVGDLYVGKTSLIHRLCKNVFDHDYKATIGVDFEIERFEIAGIPYSLQIWDTAGQEKFKCIASAYYRGAQVIITAFDLTDVQTLEHTRQWLEDVLRENEAGSCFIFLVGTKKDLLSGAACEQAEAEAVHLANEMQAEYWSVSAKTGENVKAFFSRVAALAFEQSVLQDLEKRPSTQSQVGDGDGDLIRIEVPKTQENKRPPGLGCC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein Rab-36.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid-anchor.
Protein: SELU_SALPC
Sequence: MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: LIPA_TRYB2
Sequence: MFQRWSFALCRPIVAAAQVSQQQVPPSEEPRNESGAANPPLVKEEFLRQFRERLANDKTGRNSLEGFLDLPENLPPTAASIGPLKRGKEPLPPWLKLKVPMGASRQPRFNKIRRNMREKRLATVCEEAKCPNIGECWGGGDEEGDGTATATIMVMGAHCTRGCRFCSVMTSRTPPPLDPEEPRKTADAVADMGVEYIVMTMVDRDDLADGGAAHVVRCVTAVKERNPGLLLEALVGDFHGDLKLVEMVAGSPLNVYAHNIECVERITPNVRDRRASYRQSLKVLEHVNNFTKGAMLTKSSIMLGLGEKEEEVRQTLRDLRTAGVSAVTLGQYLQPSRTRLKVSRYAHPKEFEMWEKEALDMGFLYCASGPMVRSSYRAGEYYIKNILKQRETVEAPSVSDGGNEPKDSE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACEK_YERPE
Sequence: MVAKLEQLIAQTILQGFDAQYGRFLEVTAGAQHRFEQADWHAVQQAMKKRIHLYDHHVGLVVEQLKYITDQRHFDVEFLARVKEIYTGLLPDYPRFEIAESFFNSVYCRLFKHRDLTPDKLFVFSSQPERRFREIPRPLARDFIPKGDLSGMLQMVLNDLSLRLHWENLSRDIDYIVMAIRQAFTDEQLASAHFQIANELFYRNKAAWLVGKLRLNGDIYPFLLPIHHNESGELFIDTCLTSKAEASIVFGFARSYFMVYVPLPAAMVEWLREILPGKSTAELYTAIGCQKHGKTESYREYLAFIHQSSEQFIIAPGVKGMVMLVFTLPSFDRVFKVIKDQFAPQKEVTQARVLECYQLVKEHDRVGRMADTQEYENFVIDKHRISPELLAELQHEVPEKLEDLGDKIVIKHLYMERRMTPLNLYMEQADDQQLKDAIEEYGNAIKQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDEMASEPWYSVSPNDVFPEEFRHFLCSDRKVRHFFEEMHGDLFQASYWRGLQQRIRDGHVEDVFAYRRKQRFSQRALN
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_THEM4
Sequence: MNVAVILFGGKGERFSKDYPKQFVKFHGKTLMEHTVEKFLENFIHLIIIVVNGEYLEESKKILKKYKRKNIYVILGGKTREFSTLNAVKYLKDLISEDDNVIIHDGARPFVSKEVILRNIDFVNKYGAVVTAVPVENTIAFVENKIVKEIPPRRYLFTLQTPQTFKYSILYKSFRLIKDLEKFTDDSSVVLAAGYNVHVVYGEKTNIKITTKEDLYLIGVEKIEGNI
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.