PharMolix/UniProtQA huggingface dataset:
Protein: AROA_GEOTN
Sequence: MEGCCMQLPTNVSSLRGTIEVPGDKSISHRAVMLGALASGRTVIDHFLPGADCLSTIDCFRKLGVDIHQDGTNVIVEGAGSGGLREPAAVLDVGNSGTTARLLLGILAGQPFHACLVGDESIAQRPMARVTKPLREMGAHIDGRDDGNYTPLAIRGGALRPLRYTSPVASAQVKSAILLAGLFTDGVTSVTEPHRSRDHTERMIRLFGGEVNVDGLTVSIAGPQSLRGTHIYVPGDISSAAFFLVAGAIVPNSEITLKNVGLNPTRTGIIDVLERMGADITIDHIRNEETEPIGDITIRTSTLHAIEIGGDIIPRLIDEIPIIALLATQAEGTTIIKDASELKVKETNRIDTVVAELKKFGADIEATDDGMIIRGKTALYADGIVVDSHGDHRIGMMLAIAACCAKGTARLERPEAVAVSYPAFFADLRSLL
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FARS_ZEADI
Sequence: MDATAFHPSLWGDFFVKYKPPTAPKRGHMTQRAELLKEEVRKTLKAAANQIKNALDLIITLQRLGLDHHYENEISELLRFVYSSSDYDDKDLYVVSLRFYLLRKHGHCVSSDVFTSFKDEEGNFVVDDTKCLLSLYNAAYLRTHGEKVLDEAITFTRRQLEALLLDSLEPALADEVHLTLQTPLFRRLRILEAVNYIPIYGKEAGRNEAILELAKLNFNLAQLIYCEELKEITLWWKQLNVETNLSFIRDRIVECHFWMTGACCEPQYSLSRVIATKMTALITVLDDMMDTYSTTEEAMLLAEAIYRWEESAAELLPGYMKDFYLYLLKTIDSCGDELGPNRSFRTFYLKEMLKVFVRGSSQEIKWRNENYVPKTISEHLEHSGPTVGAFQVACSSFVGMGDNITKESFEWLLTYPELVKSLMNIARLLNDTASTKREQNAGHHVSTVQCYMLKHGTTMDEACDKIKELTEDSWKDMMELYLTPTEHPKLIAQTIVDFARTADYMYKETDGFTFSHTIKDMIAKLFVDPISLF
What is the function of this protein?
Sesquiterpene cyclase catalyzing the production of sixfold more beta-farnesene than alpha-bergamotene from farnesyl diphosphate.  Involved in indirect defense by producing volatile signals attracting natural enemies of herbivores.
What are the official names of this protein?
(E)-beta-farnesene synthase, Terpene synthase 10.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_BLOPB
Sequence: MNYTIDTVVAISTPPGRGGIGIIRISGKSVPEIAPKLLGKIPNPRKAEYLPFLDTDGSILERVIALFFPEPNSFTGENILEIHGHGGQIILDILLERILKTSSDIRIAHPGEFTKRAFLNNKIDLVQAEAIADIIDATSYQAAKSASNSLQGIFSRKIYIILEQLTNLRMYAESSIDFSEDEISIIPYEDIKKKLRNIISDVQKMYKSTYHGVLLREGIKIVIAGKPNAGKSSLFNALVGIDRAIISTISGTTRDTLHEYIQLNGIAFHITDTAGLQKKSDNEIEQIGMKRTWEELSNADHILWVIDPNDVTNKENDITLKHVEKVLFCKNKKTPITIIHNKSDLTKNQIGISIINNYTIITLSALFNDGTDLLQEYLSNNIKSKIQQDCKSNLSENQGNFIARRRHLNALEKSSKYLFSAQTQLLSTMSINELFAEDLGLAHKELSKIFGKFTPDDLLKRIFSTFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATB_PHEZH
Sequence: MLPEIGAAELLIIAAVALIVVGPKDLPLLMRRIGQFMAKVRSMASEFRASFDDMARQSELDDLRKEVEAMRRGQFADMSIADGAMTEAAGDIEKSLAGVGVQLHSPTGYENTVEPPPPEPEPQPAAEPAPKPARKPRAAKPKAAAAPKAAAKPKAAAKPKPKPKTPGLKARKTAGSAE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: METJ_SALNS
Sequence: MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGIDPETWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TERPA_PSESP
Sequence: MGERRDTTVIVGAGHAGTAAAFFLREFGYHGRVLLLSAETQHPYQRPPLSKEYLLAQHSTPSLLKGKDSYARADIELCLQDDVLSITPASRQVKSSQGSYTYDHLILATGSHPRFMATLGQADNLCYLSDWDDAGRIRQQLGEASRIVVLGGGFIGLEIASSACKMGKHVTVIERAPRLLSRVVSEAFATFIGDIHLGNGIELRLGEEVREVRRCTSGVRVDAVFLSDGQLLECDMLVIGVGSEPRMELATAAGLACASGVLVDEHCHTSDPFISAIGDCVAVCPSPGHQLPRRESVQNATEQARLVAARLSGRPVPPVQTPWFWSDQLQARINLAGERPAQGQVIVRRYGGDKVSMLYLQDQQLVAIEACNMPGDCLLARRAIGQNHSLDLARLVDADVPLKDALHFA
What is the function of this protein?
The oxidation of alpha-terpineol by cytochrome p450-TERP requires the participation of a flavoprotein, terpredoxin reductase, and an iron-sulfur protein, terpredoxin, to mediate the transfer of electrons from NADH to P450 for oxygen activation.
What are the official names of this protein?
Terpredoxin reductase.
Protein: VF125_ASFK5
Sequence: MAVYAKDLDNNKELNQKLINDQLKIIDTLLLAEKKNFLVYELPAHFDFSSGDPLGSQRDIYYAIIKSLEERGFTVKICMKGDRALLFITWKKIQSIEINKKEEYLRMHFIQDEEKAFYCKFLESR
What are the official names of this protein?
Uncharacterized protein B125R, pB125R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B125R family.
Protein: CCME_WOLWR
Sequence: MKKKHKRLLITSGIFCFLSCIVFFILTTLKENISFFYTVSEAIVLQNSQKLIRVGGMVVENSVIRSESEVIFQMTDFNKSVVVKYQGILPPMFSEKSGVVVQGKMFDNSTFLADTVFAKHDENYMPKVLKQIP
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SODF_HELPY
Sequence: MFTLRELPFAKDSMGDFLSPVAFDFHHGKHHQTYVNNLNNLIKGTDFEKSSLFDILTKSSGGVFNNAAQIYNHDFYWDCLSPKATALSDELKGALEKDFGSLEKFKEDFIKSATTLFGSGWNWAAYNLDTQKIEIIQTSNAQTPVTDKKVPLLVVDVWEHAYYIDHKNARPVYLEKFYGHINWHFVSQCYEWAKKEGLGSVDYYINELVHKKA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: UREE_ACET2
Sequence: MIVERVLYNIKDIDLEKLEVDFVDIEWYEVQKKILRKLSSNGIEVGIRNSNGEALKEGDVLWQEGNKVLVVRIPYCDCIVLKPQNMYEMGKTCYEMGNRHAPLFIDGDELMTPYDEPLMQALIKCGLSPYKKSCKLTTPLGGNLHGYSHSHSH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_ALBFT
Sequence: MRLMISVLAICIGASLGALARWRLGLWLNPGAVLPLGTLAANLIGGYLIGICVAVFQALPNLDPVWRLALITGFLGGLTTFSSFSAEVVGMLGQQRYALGFGTAGLHLFGSLLLTLAGIKTATFLIAFNT
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: USTT_ASPFN
Sequence: MSGTSPPTPKDHITMVDHDYSDCSEDVSLIGADREHRRSSTPDGLYQHKINRHYNPLYIAVVASLTFLITDIAGQIIVAPRLAIFEHIICKAYYTQVSGAAGTGMGDCKVEPVQSELALINGWREMFDNIPGTSYTLDRFGRKKVLLIAMVGCLLSDIWVGVVTWFPDTFPLRAVWFSGIWQLIGGGGASISSMAFAMIADSCPADLRTTAFSQVHAAVLVAELVSVPAGAALANFNPWIPVFGAAIFMVLGILFAYVVVPDVRPAGSKREGGSDGDFLSSAQESHPTWLMSIHHRWRKIVDEFRKDSSWIRDVNVLLIMASFFVCQLGRMISGITLQYAAAKFHWKFDKASLLVSLRAGVNLFVLAAIIPALSYILVKRFKLNDVVKDKRITQINGVCLIIGSFVMFLAASPGTLVFGQTVFALGFAFSVTARSFLTGMVDPMHIGTVFTGVTTMLYGGLVIGSPMLAKTLQWGLQLGGIWVGLPFLLAAVLFTLALGAISAARSY
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of the secondary metabolite ustiloxin B, an antimitotic tetrapeptide (PubMed:24841822, PubMed:27166860, PubMed:26703898).  Probably involved in self-resistance through the export of ustiloxin B (PubMed:24841822).
What are the official names of this protein?
Efflux pump ustT, Ustiloxin B biosynthesis protein T.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPP_GEOSW
Sequence: MNLIPTVIEQTSRGERAYDIYSRLLKDRIIILGSPIDDQVANSIVSQLLFLAAEDPEKDISLYINSPGGSITAGLAIYDTMQFIKPDVSTICIGMAASMGAFLLAAGAKGKRFALPNSEIMIHQPLGGAQGQATEIEIAAKRILFLRDKLNRILAENTGQPVEVIERDTDRDNFMTAQKAQEYGIIDRVLTRIDEK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3697_BACC0
Sequence: MPIWLGILVGVVALVAGVALGFFIARKYMMNYLQKNPPINEQMLKMMMMQMGQKPSQKKINQMMSAMNKQQMK
What are the official names of this protein?
UPF0154 protein BCAH820_3697.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PA2HG_OXYSC
Sequence: MHPAHLLVLLAVCVSLLGSSEIPQPSLDFEQFSNMIQCTIPCGESCLAYMDYGCYCGPGGSGTPIDDLDRCCKTHDECYAEAGKLSACKSVLSEPNNDTYSYECNEGQLTCNDDNDECKAFICNCDRTAVTCFAGAPYNDLNYNIGMIEHCK
What is the function of this protein?
Monomer (gamma chain): Snake venom phospholipase A2 homolog that is neither toxic nor enzymatically active.  Does not bind calcium (PubMed:22776098).
What are the official names of this protein?
Acidic phospholipase A2 homolog taipoxin gamma chain, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COAD_SHEB5
Sequence: MHTRAIYPGTFDPITNGHADLIERAAKLFKHVVIGIAANPSKQPRFTLEERVELVNRVTAHLDNVEVVGFSGLLVDFAKEQKASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVNQFVHSEVATALAAKLKLAKP
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAGE1_MACFA
Sequence: MNKDYQIFWPSPSDPVRFEVDTSHEKVESISESDTMNVSNLSQGIMLSDSPICMETTSTTCDLPQNEIKNFERENEYESTLCEDAYGTLDNLLNDNNIENYSKNVLTQPVDTISISSLRQFDTVCKFHCVEAFDDEMTEKPEFQSQVYNYAKDNNIKQDSFREENPMETSVSASTDQLGNEYFRQPPPRSPPLIHCSGETLKFPEKSLAKSTAKESALNPSQPPSFVCKTAVPSKEIQNYGEIPEMSVSYAKEVTAEGVERPEIVSTWSSAGISWRSKASQENCEMPDMEQSAESLQPVQEDMALNEILKKLKHTNRKQEARIQELQCSNLYLEKRVKELQMKTTKQQVFIDVIDKLKENVEELIEEKYKIILEKNDTKKTLQNLQEILANTQKHLQESRNDKEMLQLQFKKIKANYVRLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVKRLQQLRKEQEKVTASALDLLKREKETQEQEFLSLQEEFQKRDKANLEERQKLKSRLEKLLTQVKNLQFMSENERAKNIKLQQQINEVKNENKKLKQHVARSEEQNYVPKSETAQLKEQLEEVMKSDITKDTKMTHSNLLLDCSPCEEESLNPADIERSSQLASKMHSLLALMVGLLKCQDITNSDAEHFKESEKVSDIMLQRLKSLHLKKKNLDKELLKHKDRITTFRDLIAKEKAFQDHAIKVTDCDSDEAKSIRDVPTFLGAKLDKYHSLNEELDFLITKLGCLLESKESHCNRLIEENDKYQRHLGSLIKKVTSYEEIIECADQRLAISHSQIAHLEKRNKHLEDLIRKPREKARKPRSKSLENHPKSMTMMPAVFKENRNDLD
What are the official names of this protein?
Cancer-associated gene 1 protein homolog, CAGE-1.
Protein: KDSB_BURP1
Sequence: MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLDAVREHGFDAVLTRADHPSGTDRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYFSRAPIPWSRDAYLPHWPNVAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHAPEAGIDTPADLERVQALFRSRAK
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALD3_HUMAN
Sequence: MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSEAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQFGGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCPLLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGADIGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF
What is the function of this protein?
As a component of tight junctions, plays a role in paracellular ion conductivity.
What are the official names of this protein?
MARVEL domain-containing protein 3.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell junction, tight junction.
Protein: COPB_ENTHA
Sequence: MNNGIDPENETNKKGAIGKNPEEKITVEQTNTKNNLQEHGKMENMDQHHTHGHMERHQQMDHGHMSGMDHSHMDHEDMSGMNHSHMGHENMSGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGMSFPFQVTFPGSNWVVLVLATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYVYSVYSFIANLINPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASDALQKLAELLPESVKRLKKDGTEETVSLKEVHEGDRLIVRAGDKMPTDGTIDKGHTIVDESAVTGESKGVKKQVGDSVIGGSINGDGTIEITVTGTGENGYLAKVMEMVRKAQGEKSKLEFLSDKVAKWLFYVALVVGIIAFIAWLFLANLPDALERMVTVFIIACPHALGLAIPLVVARSTSIAAKNGLLLKNRNAMEQANDLDVIMLDKTGTLTQGKFTVTGIEILDEAYQEEEILKYIGALEAHANHPLAIGIMNYLKEKKITPYQAQEQKNLAGVGLEATVEDKDVKIINEKEAKRLGLKIDPERLKNYEAQGNTVSFLVVSDKLVAVIALGDVIKPEAKEFIQAIKEKNIIPVMLTGDNPKAAQAVAEYLGINEYYGGLLPDDKEAIVQRYLDQGKKVIMVGDGINDAPSLARATIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLELAKETRRKMIQNLWWGAGYNIIAIPLAAGILAPIGLILSPAVGAVLMSLSTVVVALNALTLK
What is the function of this protein?
Involved in copper export.  Can also export silver.
What are the official names of this protein?
Copper-exporting P-type ATPase B, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPRR3_MOUSE
Sequence: MSSYQQKQPFVPPPQPEQHQVKQPCQPPPQGKFVPIATSEPCHTDVPQPGNTKIPEPCSTKVPEPGNTVVLEPDYTTMPGPCSTNITEPDYTTIPGPCSTNITEPDYTTIPGPCSTNIPGPDRTVVPGSCSTNITEPDYTTIPGPSSTKIPDPGCAMVPGPSPSSTSEPSSEPCSINVREPGYMNASEPTHAKVPDQGYTKIPDQGSSKVPEPCQSRVPEVCPPTVTPVSAKQKTKQK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.
What are the official names of this protein?
Small proline-rich protein 3, Cornifin beta.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_PELPD
Sequence: MKTEVAKIENVKRDWYLVDAQEMVLGRLASQIANILRGKNKAIYTPSVDTGDFVIVVNAEKIALTGRKLADKSYYSHSGFPGGLKEISAGKLLEKKPEELIKRAVKGMLPKNKLSRHMLKKLKIYAGSSHPHDAQQPKVLAL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL5_CLOB8
Sequence: MTRLQEKYQKEVVPAMIEKFGYKNIMEVPKLEKIVINMGVGEAKENQKVLESAVNDLTLIAGQKPVLTRAKKSVANFKIRENMPLGCKVTLRKANMFEFADKLMSIALPRVRDFRGVSSKAFDGRGNYSLGIKEQLIFPEIEYDKIDKVRGMDIIFVTTANTDEEARELLRFLGMPFAQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: IP2X_SOLTU
Sequence: MAIHKEVSFLAYLLVLGMLLFVSAMEHVDAKACTLECGNLGYGICPRSEGSPENPICTNCCAGYKGCNYYSANGTFICEGQSHPKNPKACPRNCDPHIAYSKCPRSGGKTLIYPTGCTTCCTGYTDCYYFGKDGKFVCEGESIEPKACTLECDSRLHT
What are the official names of this protein?
Proteinase inhibitor type-2, Proteinase inhibitor type II.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I20 (potato type II proteinase inhibitor) family.
Protein: EIF3I_NEOFI
Sequence: MRPILLSGHERSLNQIKFNRDGDLLFSVAKDKIVCAWWSANGERLGTYSGHQGAIWTVDVSPNTVLLATGSADNTVRLWNVKTGECVKVWDFPTAVKRVEFNPDGSRLLAVTEKRMGFLGTIAVLDISYGDSQGGALENQADEPSLRITCTESKATVAGWSYLGKYIIAGHEDGSVSQYDGKTGEQLENVQAHEFDHQINDIQFSQDRTYFITASKDKSAKLISSRNLAILKTYVADTPLNSATITPKKDYVILGGGQAAMDVTTTSARQGKFEARFYHKVFEDEIGRVRGHFGPLNTVDVHPNGTAYASGGEDGYVRVHHFDKPYFDFMYEVEREQLRK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_SHIBS
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAITANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVITTPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTALQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSIFPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINGINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: NADD_HYDCU
Sequence: MQTNRLIGINGGTFDPIHFGHLRPALEVLHALHLDEMRFIPAYQPVHRASPSVSAQQRCEMVQLAIQNQPSFKLDTIELDLGGPSYTVNTLEALKKAEPDASFVLMMGTDAFAKFNQWHDWQGVLNLANIVVTHRPGEPVPRDGEVGQIFMNHWVPNLTEASGQIVDLPVTQLDLSATALRSYLKNGDPVDYLMPENVARYIYEHQLYQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: TXA3A_SCOMO
Sequence: MYKFIFIFFTVFFLINIIEESXTXKVEDLPLPKSYTNALQQHLEKDKKRPDLQELTKKNFKTNRKSCMTNCSHVEGCFLLSPECCPKMTPTCLELDIVKEHLKKN
What are the official names of this protein?
U-scoloptoxin(10)-Sm3a, U-SLPTX(10)-Sm3a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YVCD_BACSU
Sequence: MGKHTSEHKNHAQIVQLLQDGQYFFHKGLKAYKERNLKRASKLIQRAVHLEPEDSEMLSQLAVIYSEMGQYQESNDLLDYIMANLEAEMPECHYFKANNFAHLGLFQEAYKEAAAYSDADPDGEFAEENDSLLDLLDLGDDGIEDSLYDQDELLVKQDRAKSLLESGQLAEAVAALEEITTEYPELWSAYNNLALAYFYSGNVVKAKQTAYEVLSHNEGNLHALCNLLVFYYYEREDEKVAELSDQLSNVYPMLLEQRYKLGATLALVGRYEIGYKWLKSLYKTGFEGDDTFFYWLSCSAYFTGHTDFAETIWRKVESQYPGEDRPAPWIERREALPSSVEQRLAAYYISSTKGETEHLEAVIRSKRITAPFETHFVKLLLNGDSAAADVSEDALFAYQTVKLLEQAEKEEMKTEVMSCWVFHVIQQIRAAAPLKNEKGWAAAICYIWKEAHGKQDTKKDTAARFGISPATLTKYMKYIDDILE
What are the official names of this protein?
TPR repeat-containing protein YvcD.
Protein: TGT_BORT9
Sequence: MFSIIKNDKNSNARLGVLELPHGKVETPCFMPVGTLGAMKALKHDVLEKLGCDLMLANTYHLYLRPGIDVIKKYGSLHNFTAWDKNFLTDSGGFQVFSLANFRKIETEGVDFKSHIDGSRHYFTPESVFKMQEIFESDIIMALDICSSYGIDYSEASLYTNITTSWARRTLRAYENRKEGYDGLLFLITQGNFFKDLRKRSTEAILELDSPGIAIGGISVGEPRDKYLEILEYNSSLIPKVKPKYVMGIGTPHYILDAIYYGIDIFDCVNPTRIARHGSLLTDNGILRIKRAEFNFDTCPVERDCSCTLCTRYSRGYLRHLIKSEETLGVMLASEHNIHYMFRLIKKARNAIMNGDFTKFRKLYLSKYDEGNFDE
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: LCD1_CANGA
Sequence: MLRDKLKLLQAQIEQERSKSNYRVNEVKEEFDKEIQKLRQQLQSLEDEKKFLVLESRGINAVNQRIKTSPPEAFSRVSSQHRALNTPDSSHIQEHIPKKRKTEISTQPSIVLNPNRVIKDEVSAFFDCLYVHRIVGVELSTIEILNCIKFEHIDEFNYKLLKINKDTSIGSGIVDFLQSCKKNMKLNELVDSVLEHLATLIKAIIINDQELNFSVPFLVALMVQTILFRPSAVSVNSLKDLFIFTCDLIRKFQIVLKKPLHKSPLEVDLGPQIFQYELIDNLILVYSFDLLESTTKVIRIQQLSETLYMEFFDESLMKSLEAVYKLTLTISFKPVINVIYSMVAVFVTITNIMNNDNLSKPFGSSKWWSDLLTRLYQLLGKRILNFHVFDDTNTNNMHIDRFFDFYSLLRNMGTNSVSPLLAQLVTRGEIKGIPNIVLKDDIIDKYESKKEKGVLSDNLELEKWFVYLKDDILSIIENLMGYFKKDSKITNGEILINLTKLISVEQSQFMDHLIDQDTDVFAVRMNLVEHALSIIYRMWKYYEENITQESIKEVESELVMSLWRIIVCKHASKKICKDDLMEHRILINQMENLHLQDTIDLYEDAFEDMPEYIKEELECSINNGTQQKMQVQYDDIYIEMARYILESKLTNFISVENTDSLYLSMGF
What is the function of this protein?
Forms a complex with the serine/threonine kinase MEC1 which activates checkpoint signaling upon genotoxic stresses.  The MEC1-LCD1 complex is recruited to DNA lesions in order to initiates the DNA repair by homologous recombination.  Required for cell growth and meiotic recombination (By similarity).
What are the official names of this protein?
DNA damage checkpoint protein LCD1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.