PharMolix/UniProtQA huggingface dataset:
Protein: GLNA1_MEDSA
Sequence: MSLLSDLINLDLSETTEKIIAEYIWIGGSGLDLRSKARTLPGPVTDPSQLPKWNYDGSSTGQAPGEDSEVIIYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRHAAAKIFSHPDVVAEVPWYGIEQEYTLLQKDINWPLGWPVGGFPGPQGPYYCGAGADKAFGRDIVDSHYKACLYAGINISGINGEVMPGQWEFQVGPSVGISAGDEIWVARYILERITEVAGVVLSFDPKPIKGDWNGAGAHTNYSTKSMREDGGYEVILKAIEKLGKKHKEHIAAYGEGNERRLTGRHETADINTFLWGVANRGASIRVGRDTEKAGKGYFEDRRPSSNMDPYVVTSMIADTTILWKP
What are the official names of this protein?
Glutamine synthetase cytosolic isozyme, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_BRUME
Sequence: MARSVWKGPFVDGYLLKKAEKVREGGRNEVIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSEEMVGHKFGEFAPTRTYYGHGADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PUR5_STACT
Sequence: MAESYKNAGVDIHAGYEAVERMKSHVQRTMRKEVLGGLGGFGAAFDLSQLNMQKPVLVSGTDGVGTKLKLAIDHDKHDTIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGVSDGCEETNTALIGGETAEMGEMYHEGEYDLAGFAVGAVEKDDYIDGSTVKPGQVIIGLASSGIHSNGYSLVRHLIKASEVDLNAEFENGKSYLDTFLEPTRLYVKPVLAVKEQVKLYAMTHITGGGFYENIPRALPEGVTAEIDVQSFPTPAVFDWLQKEGNIETEEMYNIFNMGIGFTLVVDEAEAEKTLSILKEQNVDAYQIGKITEASDEPIVLTGVKA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESSC_STAAN
Sequence: MHKLIIKYNKQLKMLNLRDGKTYTISEDERADITLKSLGEVIHLEQNNQGTWQANHTSINKVLVRKGDLDDITLQLYTEADYASFAYPSIQDTMTIGPNAYDDMVIQSLMNAIIIKDFQSIQESQYVRIVHDKNTDVYINYELQEQLTNKAYIGDHIYVEGIWLEVQADGLNVLSQNTVASSLIRLTQEMPHAQADDYNTYHRSPRIIHREPTDDIKIERPPQPIQKNNTVIWRSIIPPLVMIALTVVIFLVRPIGIYILMMIGMSTVTIVFGITTYFSEKKKYNKDVEKREKDYKAYLDNKSKEINKAIKAQRFSLNYHYPTVAEIKDIVETKAPRIYEKTSHHHDFLHYKLGIANVEKSFKLDYQEEEFNQRRDELFDDAKELYEFYTDVEQAPLINDLNHGPIAYIGARHLILEELEKMLIQLSTFHSYHDLEFLFVTREDEVETLKWARWLPHMTLRGQNIRGFVYNQRTRDQILTSIYSMIKERIQAVRERSRSNEQIIFTPQLVFVITDMSLIIDHVILEYVNQDLSEYGISLIFVEDVIESLPEHVDTIIDIKSRTEGELITKEKELVQLKFTPENIDNVDKEYIARRLANLIHVEHLKNAIPDSITFLEMYNVKEVDQLDVVNRWRQNETYKTMAVPLGVRGKDDILSLNLHEKAHGPHGLVAGTTGSGKSEIIQSYILSLAINFHPHEVAFLLIDYKGGGMANLFKDLVHLVGTITNLDGDEAMRALTSIKAELRKRQRLFGEHDVNHINQYHKLFKEGVATEPMPHLFIISDEFAELKSEQPDFMKELVSTARIGRSLGIHLILATQKPSGVVDDQIWSNSKFKLALKVQDRQDSNEILKTPDAADITLPGRAYLQVGNNEIYELFQSAWSGATYDIEGDKLEVEDKTIYMINDYGQLQAINKDLSGLEDEETKENQTELEAVIDHIESITTRLEIEEVKRPWLPPLPENVYQEDLVETDFRKLWSDDAKEVELTLGLKDVPEEQYQGPMVLQLKKAGHIALIGSPGYGRTTFLHNIIFDVARHHRPDQAHMYLFDFGTNGLMPVTDIPHVADYFTVDQEDKIAKAIRIFNDEIDRRKKILSQYRVTSISEYRKLTGETIPYVFILIDNFDAVKDSPFQEVFENMMIKMTREGLALDMQVTLTASRANAMKTPMYINMKTRIAMFLYDKSEVSNVVGQQKFAVKDVVGRALLSSDDNVSFHIGQPFKHDETKSYNDQINDEVSAMTEFYKGETPNDIPMMPDEIKYEDYRESLSLPDIVANGALPIGLDYEGVTLQKIKLTEPAMISSENPREIAHIAEIMMKEIDILNEKYAICIADSSGEFKAYRHQVANFAEEREDIKAIHQLMIEDLKQREMDGPFEKDSLYIINDFKTYIDCTYIPEDDVKKLITKGPELGLNILFVGIHKELIDAYDKQIDVARKMINQFSIGIRISDQQFFKFRFIQREPVIKENEAYMVANQAYQKIRWFK
What is the function of this protein?
Component of the type VII secretion system (Ess).  Required for the secretion of substrates including EsxA and EsxB.  However, unable to support secretion of the substrate protein EsxC.
What are the official names of this protein?
Type VII secretion system protein EssC.
What is the protein family that this protein belongs to?
Belongs to the EssC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PREU1_PREIS
Sequence: MASGPRNDDIAIVGLACRFPGGASNETKLWDLLSNRESAFTEVPPERFNVDAYHHPSPNKLNTLNSRGAHFMHEDVSAFDAPFFGITAQEANAMDPAARMLLELTFEALESAGQKLEDVAGSDTSCYVGCFTRDYHEMLYRDIESAPMYTGTGTGFSLFSNRISWFYDFRGPSMTLDTACSSSLVGLHLACRGLQAGESKMAVVCGANVILSPDIALTLSNLHMLSMDGLSRSFAEGTTGYGRGEGIASLILKRVEDALRDGDPIRAVIRGSGVNQDGHTKGITVPSSEAQADLIQTVYSSAGLDPSETGYFEAHGTGTAVGDPLELGAIAKSISKSRKVENKLVVGSIKSNIGHLEGAAGLAGVIKSVLMVEKNAILPNIHFEKPNRRIPFEQWKIKIPTELMPWPASGVRRASVNSFGYGGTNAHVILDDAESYLQKRLSNGHSEENGMELLKETRIFLLSARDEASLERLKQVYSDYIADVAGRRSPDNLFDESAYLDGLAYTLGCRRSVFPCRSFITASTLSELQESLSVQRLISTKAATSSRLGFVFTGQGAQWARMGLVLMDYPVFAQSIQEADRYLSEELRSSWSVLEELGKDAEHSQIGLAEFSQPLCTILQVALVDLLTSWQILPATVVGHSSGEIAAAYSFGAITKQDAWKISYWRGQLCAQLPLKRPELRGAMMAVGLGREEALSYIEKTGNGQAVIACVNSPSSVTLSGDETAINDIESALQAQNIFARKLNVQNAYHSHHMQPLADEYLAALEGLSTLSQEKAGTVKMASSVTGALINHTDLGPSYWVQNLVSPVLFSNAVEALLKQSTKGRRQARANEPAFDYLVEIGPHAALKGPLRQILQAHEASQIPYSSVLMRGEDGPVAALSAAGDLVCRGIQVDIKAVNRFQGRAIPLTNLPTYPWNHSLKYWADSRVSRARQHRKYGRHDLLGAPTQDSDELEPRWRHFLRVSDNPWIQDHIVHSSILYPGSGILAMPLHALQTLADSHRDVESIGLRDVSIVKAIVVPDDQFGLEVFLRMRRQRPRNGTWNGWWEFSVCSNQENDHVEEHGFGLGKIHYRPEKDTSVKTATNHVNDEFEREFDEVQATSTASISPVDFYAVAKSVGLTYGPSFQGLTEINAGNAKCSWKIQVPDTQKIMPAGVESPHIVHPTTLDIVFHSLFAAIGDGHLDMQHAAVPIGLKSMKISVDLPTGGNTFLKGISKVSRDAGRDIVADIRVAAESSNTPSIIVEGLRCRELPNGNSQSGPSETIKAPIGHVVQKIDVDLIEPIQLAQHIQKRFLERKEDGTLASEDLGEAIITIVDLVAHKNPRSSLLQVGGVTPELTQRILSNLEADNVSAKRFKNIKVVDANQELISQLETQYATPAGTVQFEKVTLDEAQSLAELKESSIDLAIVNIEELHSDKVSEYLANVLRSLKPGGKVLKIDSAGRNGAIGASDTLSFDTLCAGPEHVLSFATKGTAEKANTENFRTVILLPRCPSENVKKVASALEQVITVKGAIDTVIWSAEMPSLENSSTVISLLEFDDAFVADLSEEDFSSLKTLALGVKRILWVAHGTDPQMQTAAGWLRSLSNENMGIDYCYLLLESATDQEALDVAKLIERVSSTEEMEREYTERDDGLCCSRWAAKTELSALVGADSDQSKDATMRLGEARHGLTLTGKRGKLPSDARFTSVDVLDQNLTENEVMIDVRSVLLSTNDVQGTGQTGWREAAGVVVATGTAGSFEVGTAVSFVYDGPISTKAKINSKYCSTLSGTPEFQDALLQSVTYPTVYHGLCTLGQLRCDKTIFVQGGSSILGQAAISLARRLGATVFASVRDEEQNSILQRLGVPSDKILNDNVCERSSIIKRVNEGRGFDVIFNATGDEETIAELWQCIARGGKFINADANKKDTPATFNLSAKPFTMGASFEIIDMNEYLTNDFSTYQSIRDESESFRTRCSAVGLQIPVFTAGNIHEALDSVHVPTGLGKAVLLFSPDSKIPVSPDVKNQLRLRPDATYVLAGGLGGLGRSLAKLMVGSGARHLAFLSRSGPGSAAAQSISEEFSPLGVTVNFYGCDVADSESVSHTFGNIAKNQALPPIRGIIQSAAVLRDSIFENMSHTQWTEAVRPKVQGSWNLHQASLSGPCAKEGLDFFVMLASISGFVGNRGQANYAGGNSFQDALAKYRKSLGLAATSVDLGLMQDIGLIAERGGQSNLSDDTVVPLTAKDFELIFKLAMNSEGHDVPAQIVTGLPTGGILQKQGIETLPFYYRDPRFSAMQFMDLDETLTSAGGSAGNESVSMEEQLASAKSREQANGIVLEALRAQVAKALRCPAEDIDTARPLHYYGMDSLMAVDMRGWVQGKLKAEISLFDVMSGSSISALAEKISKASKLIKAELE
What is the function of this protein?
Highly reducing polyketide synthase; part of a gene cluster that mediates the biosynthesis of a yet unidentified natural product.
What are the official names of this protein?
Highly reducing polyketide synthase Preu1, biosynthesis protein Preu1.
Protein: KALM_COTJA
Sequence: MVRRAPGASLALLLWVTAVSCSPAGPGAATARRQDEAFSTARLTSRCLSLQITRISAFFKHFQDNGSLAWCQNYKQCSKCLEPCKESWDLKRNHCQSFCEPLFPKKNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACFESCEADSECSGVKKCCSNGCGHTCQVPKNLYKGVPLKPRKELKFIELQSGDLEVKWSSKFNISIEPVIYVVQRRWNQGIHPSEDDATNWQTVAQTTDERVQLSDIRASRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPSNIRIANISANNDGTVNVMITWDLPEEPDIPVHHYKVFWSWTYSKYVIPAKKKRRKITDGPQNYVVLEGLQPNSNYNVELQAVTRWGQIRLKSAKVSLHFSTTQDNRNNNEQTSVEKPPKGVVDPYPTFQRRKPTRFLKIGTPFYQDNQLQVKIYWKKSGINMNQFQVHSLLESCTHNDTKGLEKVTELTYENYMILKDLSFSCKYKVTVLPAKSKSRFKAESIFFVTPPCSTFKEKTHKHINCAAEEVPVLPKVLAKPENLSASFIVQEGNITGHFSWKISKAVLHQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPADHYVLTVPNLRPSMLYRLEVQVLTTGGEGPATIKLFRTPDLPPFLPHRPHLKHHPHRYKPPPEKY
What is the function of this protein?
May be an adhesion-like molecule with anti-protease activity.
What are the official names of this protein?
Anosmin-1, Kallmann syndrome protein homolog.
What are the subcellular locations of this protein?
Cell surface.
Protein: RRAAH_PSE14
Sequence: MHYITPDLCDAYPDLIQVVEPMFSNFGGRDSFGGQIVTVKCFEDNSLVKEQVELDGKGKGKVLVVDGGGSLRCALLGDMLAEKAARSGWEGMLIYGCIRDVDVIAQTDLGVQALASHPKKTEKRGIGDLNVLVTFGGVTFRPGEYLYADNNGVIISPSPLTMPE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: LACB_STAAU
Sequence: MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPIFGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGRIIGELLMCDIIDAFINAEYKPTEENKKLIAKIKHLETSNADQADPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: NQRD_CHLTB
Sequence: MTTNKSYLTYFTDALWINNQPLIAILGICSALAVTTTVTTALTMGFAVSFVTGCSSFVVSLLRKITPESVRMIAQLIIISLFVILIDQFLKAFFFTISKTLSVFVGLIITNCIVMGRAESMARHVSPIPAFLDGLGSGLGYGWVLVCISIIRELFGFGTILGFRVIPEILYASAAHPDGYENLGLMVLAPSAFFLLGIMIWIVNIIRAPKTKR
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CBS_HUMAN
Sequence: MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFVAAQERDQK
What is the function of this protein?
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine.  This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (PubMed:23981774, PubMed:20506325, PubMed:23974653).  Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).
What are the official names of this protein?
Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPD_CHLCH
Sequence: MSVVIASRRYANALLSVVEESNTIDKTLDEMNAISEVLHHSRDLVHALKSPLISYDKKIHIVEEVFKGRVSETVMFFLKLVGKKNRLGHLPHIVDEFKNLLDEDRGIINVDITSAVELSDEQANELVATIANMSGKQVRATLTVNEELIAGAAVKIADTIIDGTVRHQLSKLRSSLVAA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YIDC_SINMW
Sequence: MMENNRNYFVAIALSVLILIAWQFFYVSPKMEKDRIAAEKAQQAQSQPGTQQAAPGQAAPGQALPGGAIPSAAESRDQAIGKSARVAIDTPALSGSINLTGARFDDLKLKGYRETVDPKSPVITLFSPAETADGYFTEIGYIGSDATGSVPGPQTVWMLSGGDKLTPSTPVTLSYTNDKGITFTRTISVDDRYMFEVVDSIKNDAAAAVSLSSYGRVTRFNKPSTPSIYVLHEGFVGVAGEHGLQEVGYSDVEDEEPVEPGKSTGGWLGITDKYWAATIVPPQDTPFDIRFSHFADGRPRYQSDYKSDAVTVAPGQSAEVKNLIFAGAKEVPVVDNYELTYSIPNFDKLIDWGWFYFITKPMFKMMDFFFRLFGNFGIAILITTIVVKLIFFPLANKQYASMANMKKVQPKMEELKKKFGDDRMGLQQAMMQLYKEEKINPLAGCWPILIQIPVFFALYKVIYVTIEMRHAPFFGWIQDLSAPDPTTIINLFGLLPFEGPAFLHLGIWPIVMGVTMFLQMRMNPTPPDPTQAMLFTWMPVVFTFMLASFPAGLVIYWAWNNTLSILQQGIIMKRQGVKVELFDNLKSLFSKKPKPAE
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRDMT_MOUSE
Sequence: MEPLRVLELYSGIGGMHHALRESHIPAHVVAAIDVNTVANEVYKHNFPHTHLLSKTIEGISLEDFDKLSFNMILMSPPCQPFTRIGLQGDMTDPRTTSFLYILDILPRLQKLPKYILLENVKGFEVSSTRGLLIQTIEACGFQYQEFLLSPSSLGIPNSRLRYFLIAKLQSEPFPFQAPGQILMEFPKIVTVEPQKYAVVEESQPRVQRTGPRICAESSSTQSSGKDTILFKLETVEERDRKHQQDSDLSVQMLKDFLEDGDTDEYLLPPKLLLRYALLLDIVKPTSRRSMCFTKGYGSYIEGTGSVLQAAEDAQIENIYKSLPDLPPEEKIAKLSMLKLRYFTPKEIANLQGFPPEFGFPEKTTVKQRYRLLGNSLNVHVVAKLLTVLCEGFGNASESCHKMPLILDSNSKILS
What is the function of this protein?
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
What are the official names of this protein?
tRNA (cytosine(38)-C(5))-methyltransferase, DNA (cytosine-5)-methyltransferase-like protein 2, Dnmt2, DNA methyltransferase homolog MmuIIP, DNA MTase homolog MmuIIP, M.MmuIIP, Met-2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_PSE14
Sequence: MSVESFTPTALEFTPNAAHKVKTLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVADDDTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNASTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CLPB_CORGL
Sequence: MSSFNPTTKTNEAMQAALQQASSAGNPDIRPAHLLAAILEQTDGVAAPVLMATGVDPKEILAEAKKLVASYPKASGANMANPNFNRDALNAFTAAQELAGELGDEYVSTEVLLAGIARGKSDAADLLTNKGATYDAIKEAFPSVRGSQRVTTQDPEGQFQALEKYSTDLTKLAREGKIDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLKGKTLISLDLGSMVAGAKYRGEFEERLKAVLDEIKGANGEVVTFIDELHTIVGAGASGESAMDAGNMIKPLLARGELRLVGATTLNEYRKYIEKDAALERRFQQVYVGEPTVEDAIGILRGLKERYEVHHGVRIQDSALVAAAELSNRYITSRFLPDKAIDLVDEAASRLRMEIDSSPQEIDELERIVRRLEIEEMALSKESDAASKERLEKLRSELADEREKLSELKARWQNEKTAIDDVREMKEELEALRSESDIAERDGNYGRVAELRYGRIPELEKQIEDAESKVEVNENAMLTEEVTPDTIADVVSAWTGIPAGKMMQGETEKLLNMERVLGNRVVGQLEAVTAVSDAVRRSRAGVADPNRPTGSFLFLGPTGVGKTELAKAVAEFLFDDDRAMIRIDMSEYGEKHSVARLVGAPPGYVGYDQGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDILLQVLDEGRLTDGQGRTVDFRNTILILTSNLGAGGTREQMMDAVKMAFKPEFVNRLDDVVIFDRLSPEQLTSIVDIQIKQLTDRLAGRRLNLRVSDSAKAWLAERGYDPAYGARPLRRLIQQAIGDTLAKELLAGNVRDGDGVLVDVADGGQKLDVSRAV
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).  Necessary for survival of C. glutamicum at high temperatures.
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_TRACE
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: INS_SELRF
Sequence: IQSLPLLALLALSGPGTSHAAVNQHLCGSHLVEALYLVCGERGFFYSPKARRDAEHPLVNGPLHGEVGDLPFQQEEFEKVKRGIVEQCCHNTCSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC2_HELSJ
Sequence: MIKTSQIAKYIFLLKKAEFIKSEKKHVILNKTTLKKMVFILQNKYDEQTVFFILEKLKEIGFHLATQSGLSLGIDDLKSFPDKKKLITETRTDLNNNEEHFLLQNISPLEKSKYLITKWNDVNNFIIQRIKKVFLKKEPLNPLALMAFSGARGNISQVSQLIGLRGLMTDPLGKLVEFPIQGNFREGMTLTEYFISCYGARKGLVDTALRTATAGYLTRRLVYVVQHIFISIEDCNVTNGISVEINEKSSNSLIGLTLLKNFYNKNIFIAKNTIISPTLVKLLLNSYNYLSHKKSIVCRSILTCQLQHTLCQFCYGWDNARAKRVAIGEAIGIIAAQSIGEPGTQLTLRTFHTGGVGGFSGANWISYNSPFDGFIKFKKPVIGNILRSWIVMPHYTSLNLVYKLTPSFNELNLTLFIFDKLKNELYNKTLKNEGLLFVREGDFIKKGQLLFSEININFKNSNLLKTYIPYYSLETGLIISPKLALNKYLYPLWIFLFNIIKLNLDSLNSKKFTVYKNYSILEKNDLIDLKTILFEIHFIQKSKKFNLKKQEYLLYQNLKMSLCKSHYDYSTYKKLNVAFQQNNQKLNFFYNKKLKSSLVSNNINLLWTSSSYSINILTKSIFNIIVFEYLYLSLLIKNKYILWILSKNLKKKDKFHFFKYTSTSSSKIEIFRLNSKKNSLNIRKNKLFFYSQNYKKNKVSNILFGNSIFLKFPLKKINTFFSQIKQKTINLKEKKTSNVEGEFIGFQLKNNIKFWYSISPNSLFSFKKDNKKNRYNFNFIRKNSNISGFLVSNTIKTFTLQKGIPLIFPSDTIYHKMEKDFIFKNELLCSFKSLKPETQDIIQGIPRVEKLLEGRPLPFYKPKVELYKIWQFFLKNLGFLKIKNSLFNLKKVESKVYLNNFKPNLNIGDICYLAYFHSKSNFGLDIASIISNVYLQEGVNISFKHIELIVRELTSLVEIINPGDSGFIVKEKIHWLLIYNYNKRLKSLNLKEISYMPIFLGMTEITKKKNSFGVAGSFQNLREIIIDHTFTRKTDYLLGLHENVLFNKIIPAGTGFFF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: 94D18_PARPY
Sequence: MDPPSLLSLALLLLAAAAAAAFVLFPRRRSPEKKPSSGNPGSLSELIKNGHRILDWMVEILAASPTNTVATYMGVVTANPANVEHMLKTKFENYPKGDRFVTLLEDFLGRGIFNSDGDHWKLQRKTASLEFNTKTIRTFVMENVRVSVVDRLIPIFARAAASGETIDLQETLERFAFDNVCKVSFNEDTGRLSGDDTMEGREFARAFEQASELIVGRYKHPFLLSWKLMRFFNIGDERRLKEKIATVHRFATSVIRRRKSAASLGDDLLSRFIAEADYPDEFLRDIIISFVLAGRDTTSATLTWFFWLASTRPEVLARVEAEVNAVRRKNGTCAGVMFTLEEVREMDFLHAALSEALRLYPPVPLQTRACHESDEFPDGTKVRPGTTVMYNSYAMGRMKSIWGEDYAEFRPERWLDKGGGFQPRSPFRFPVFHAGPRMCLGKEMAYIQMKAVAASVVERFEVVVMDKEKVREKDYTMILRVKGGLPVRLKEKSVAAG
What is the function of this protein?
Involved in the biosynthesis of spiroketal steroid and saponin natural products from cholesterol such as diosgenin and analogs (e. g.  furostanol and spirostanol), plant defense compounds used as main precursors for the industrial production of steroid hormones (PubMed:31324795).  During the 5,6-spiroketalization of cholesterol, may catalyze the 27-monohydroxylation of furostanol-type steroid to an intermediate product that undergoes a stereospecific formation of the terminal heterocycle to yield diosgenin (PubMed:31324795).
What are the official names of this protein?
Cytochrome P450 CYP94D108, PpCYP94D108.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: LPXB_RHOCS
Sequence: MKPLLIFLIAGEPSGDVLGGRLMAALREAMEGHVEFAGVGGPRMAEQGLQSLFPMEDLALFGLAELLPRLPTLLKRLDQTTKAVLERTPDAVVSIDAPDFCFRVEQRLRRAGARMPLIHYVAPTVWAWRPGRARKVAKFLDHLLALLPFEPPYFEAVGLPCTFVGHPVVESGADAGDGERFRRRHGIAPDATVLTVLPGSRRSEVTKLLPDFGATLEILASRYPDLQVVVPTVPGVAETVAEAVQSWPVPAITLLGDADKYDAFAASTAALAASGTVALELALARVPAVIAYRIHPVSHALYRRFIRVRYVNLVNIMLDRPLVPELLQQDCTPDRLALAVDRLLNEPSARQEQIDGVTEVARWLGQGDVPPSRRAAEAVLNVITKRVIADRQGQTPGRSRS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: E4RF1_ADE02
Sequence: MAAAVEALYVVLEREGAILPRQEGFSGVYVFFSPINFVIPPMGAVMLSLRLRVCIPPGYFGRFLALTDVNQPDVFTESYIMTPDMTEELSVVLFNHGDQFFYGHAGMAVVRLMLIRVVFPVVRQASNV
What is the function of this protein?
May modulate tight-junctions functions of infected cells through interactions with PDZ proteins.  E4 ORF1 has ben show for Adenovirus 9 to interact with protein involved in tight junction regulation.  May play a role in mTOR activation by activating PI3-kinase, thus overriding cellular checkpoint for translation.
What are the official names of this protein?
Early 4 ORF1 protein, E4-ORF1, E4 ORF1 control protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E4-ORF1 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: VA5_POLGA
Sequence: NDYCKIKCSSGVHTVCQYGESTKPSKNCAGKVIKSVGPTEEEKKLIVEEHNRFRQKVAQGLETRGNPGPQPAASNMNNLVWNDEQAKIAQVWASQCQILVHDKCRNTEKYQVGQNIAYAGSSNHFPSVTKLIQLWENEVKDFNYNTGITNKNFGKVGHYTQMVWGNTKEVGCGSLKYVEKNMKIHYLICNYGPAGNYLGQPIYTKK
What are the official names of this protein?
Venom allergen 5, Antigen 5, Ag5, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACEK_PSEA7
Sequence: MVQSAPASEIAALILRGFDAYREQFREITDGARARFEQAQWQEAQRASAQRINLYEEKVAETVAGLRAGLADSELLDVERWPIIKSAYIAQIDLRLDDELAETWFNSIFCGLFSHDNISDGTMFVHTTRPSLRAHARAPYTRTYRPGGDLRQALEKIFDDYRFDVPYDDRERDLERIDALLHSNLPDWVCKDPDLAIELIGSVFYRNKGAYLVGRLFTPDEQWPLVFPLLHREGHGIQFDTVITDEAEVSIIFSFTRSYFMVDVPVPAELVAFLKRLLPGKHLAELYTSIGFYKQGKSEFYRALINHLATTDDRFVMAPGVRGMVMSVFTLPGFNTVFKIIKDRFNPSKSVDHATVIQKYQLVKNHDRVGRLADTQQFADFRFPVSKFEPECLAELLEVAPSTVVVEGDVVLIRHCWTERRMTPLNIYLENASEAQTREALNDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEICYLTEVNFRYIPEPRFPEDEMSSEPWYSVGPNDVFPEEFPRFLFVDLDQRRLFAKLHGNLYDAKYWQGLQQQIREGKVIDVFPYRRQETPEQLLK
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.