PharMolix/UniProtQA huggingface dataset:
Protein: BCAL2_ARATH
Sequence: MEVIHAWSAPRSLSTTLMYSFAQRDDIEVLDEPLYAAFLKSTGVDRPYKDELLSKMECDGEKVVKDIIYGPGKKKYRFCKHISKQRLLGLPSELMSEGKHFILIRNPLNILPSFEKIHPSSFHELGLGELVSIYSDLCQMGTPPAIIDADELQRDPEATLRSLCDDLEIPFQASMLKWEAGPIPEDGLWAPWWYETLHKSTGFSSPQKYPQTFPLMHYDLLEQCLPLYNILRCHMKHKSSLLSSTLPPPSLPVPENAKLLAWVGDEIVPREMAKVSVFDSVVQGGDSVWEGLRIYKGKVFKLEEHLDRLSDSAKALAFNNVPTREEIKEAIFRTLITNGMFDNTHIRLSLTRGKKVTSGMSPAFNRYGCTLIVLAEWKPPVYDNDGGIVLVTATTRRNSPNNLDSKIHHNNLLNNILAKIESNNANVDDAIMLDKDGFVSETNATNIFMVKKDRVLTPHADYCLPGITRATVMELVVKENFILEERRISLSEFHTADEVWTTGTMGELSPVVKIDGRVIGEGKVGPVTRRLQNAYKKLTDGSGVPIPTYQEVKNLEPCV
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: UNG_ECO45
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPR54_ARATH
Sequence: MALLRSKLHLSRTLSFISPLLPKTFSTSATSLLSDHENDESAATITAAVSVPISPLLTPEDTQTVEKFHSIIKDHYRKNPTSPNDAILNPSLTLHALSLDFSQIETSQVSPSVVRCVIEKCGSVRHGIPLHQSLAFFNWATSRDDYDHKSPHPYNEMIDLSGKVRQFDLAWHLIDLMKSRNVEISIETFTILIRRYVRAGLASEAVHCFNRMEDYGCVPDKIAFSIVISNLSRKRRASEAQSFFDSLKDRFEPDVIVYTNLVRGWCRAGEISEAEKVFKEMKLAGIEPNVYTYSIVIDALCRCGQISRAHDVFADMLDSGCAPNAITFNNLMRVHVKAGRTEKVLQVYNQMKKLGCEPDTITYNFLIEAHCRDENLENAVKVLNTMIKKKCEVNASTFNTIFRYIEKKRDVNGAHRMYSKMMEAKCEPNTVTYNILMRMFVGSKSTDMVLKMKKEMDDKEVEPNVNTYRLLVTMFCGMGHWNNAYKLFKEMVEEKCLTPSLSLYEMVLAQLRRAGQLKKHEELVEKMIQKGLVARPL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g20300, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NOP10_HALSA
Sequence: MKSDIRVCEAWRSHHDGPVYTLSETCPECGGDAVNSAPAPFDPADPHGKYRRALKERRRL
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: RRF_BACFR
Sequence: MVDVKTIIEESQEKMDMAVMYLEEALAHIRAGKASTRLLDGIRVDSYGSMVPISNVAAVTTPDARSITIKPWDKSMFRVIEKAIIDSDLGIMPENNGEIIRIGIPPLTEERRKQLAKQCKAEGETAKVSIRNARRDGIDALKKAVKDGLAEDEQKNAEAKLQKVHDKYIAKIEEMLAEKDKEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR59B_DROME
Sequence: MAVFKLIKPAPLTEKVQSRQGNIYLYRAMWLIGWIPPKEGVLRYVYLFWTCVPFAFGVFYLPVGFIISYVQEFKNFTPGEFLTSLQVCINVYGASVKSTITYLFLWRLRKTEILLDSLDKRLANDSDRERIHNMVARCNYAFLIYSFIYCGYAGSTFLSYALSGRPPWSVYNPFIDWRDGMGSLWIQAIFEYITMSFAVLQDQLSDTYPLMFTIMFRAHMEVLKDHVRSLRMDPERSEADNYQDLVNCVLDHKTILKCCDMIRPMISRTIFVQFALIGSVLGLTLVNVFFFSNFWKGVASLLFVITILLQTFPFCYTCNMLIDDAQDLSNEIFQSNWVDAEPRYKATLVLFMHHVQQPIIFIAGGIFPISMNSNITVAKFAFSIITIVRQMNLAEQFQ
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  Forms a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Also plays a role in the response to N,N-Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide.
What are the official names of this protein?
Odorant receptor 59b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUCS_BIFLO
Sequence: MRVIVADCSAEYSGRLNASLPLAKRVLLIKADSSLLIFSELGSYKPLNWMTAPCTIREIDPAAKSAQHSRESVAGGAVDGDSATHSPESVAAGEPEKVLRVSADKGSDILEVTLQHIYSDQTYDLGEDPGLIKDGVEDHLQRYLAEQIERIGKGAKLVRREYPTAIGPVDIMAVNAEGEHVAVEIKRHGGIDGVEQLTRYCELLNRDPLLAPVHGIFAAQTITPQAQVLAKDRGFTCLILDYDDMKGTEDDSLRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKG_FASHE
Sequence: YPDGFDGEAV
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Putative phosphoenolpyruvate carboxykinase [GTP], PEPCK, Newly excysted juvenile protein 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
Protein: RPOA_CHLPB
Sequence: MIYQMQMPEKIDVDEGTHNDKNGIFIAQPLERGYGVTLGNAMRRVLLASLPGTAITGIKIDGVFHEFSAIDGVREDVPDIILNLKKVRFRSSTKRSCKTTVTVDGPADVTAGDIVAQEGEFEVLNTDLHIATVNEGSRLSMDVYIGRGRGYVPAEDNRGDGMPLGFIAIDSIFTPIKNVKFSVENTRVGQRTDYEKMILDVETDGSVSPDDSISLAGKIINEHVSLFANFSPTDEEFTEEEYKQQDDEFENMRKMLLTRIEDLDLSVRSHNCLRLAEIDTLGDLVSRKEDELLTYKNFGKKSLTELKEQLEKFELKFGMDITKYQMKG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: QUEC_BDEBA
Sequence: MKKNKKVVVLLSAGLDSTVNAYEAIKHHHEIVLALTFNYGQRAAKKELEASANIAKHLGIPHKVVELPWFKDFNKSSLLVEDQAVPTGSAVEIDNQQKSEETAKSVWVPNRNGIFLNIAAAYAEALGADAVIPGFNAEEAATFPDNSREFLEQATKSLWYSTSNHVTVGCYTAHLKKPDIVRLGQGLKVPWELIWPCYFSGDKWCGQCESCLRSKRAFASANIDVKHLFKE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: CH60_HELPJ
Sequence: MAKEIKFSDSARNLLFEGVRQLHDAVKVTMGPRGRNVLIQKSYGAPSITKDGVSVAKEIELSCPVANMGAQLVKEVASKTADAAGDGTTTATVLAYSIFKEGLRNITAGANPIEVKRGMDKAAEAIINELKKASKKVGGKEEITQVATISANSDHNIGKLIADAMEKVGKDGVITVEEAKGIEDELDVVEGMQFDRGYLSPYFVTNAEKMTAQLDNAYILLTDKKISSMKDILPLLEKTMKEGKPLLIIAEDIEGEALTTLVVNKLRGVLNIAAVKAPGFGDRRKEMLKDIAILTGGQVISEELGLSLENAEVEFLGKAGRIVIDKDNTTIVDGKGHSDDVKDRVAQIKTQIASTTSDYDKEKLQERLAKLSGGVAVIKVGAASEVEMKEKKDRVDDALSATKAAVEEGIVIGGGAALIRAAQKVHLNLHDDEKVGYEIIMRAIKAPLAQIAINAGYDGGVVVNEVQKHEGHFGFNASNGKYVDMFKEGIIDPLKVERIALQNAVSVSSLLLTTEATVHEIKEEKAAPAMPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOXS_VIBCH
Sequence: MQNRHIAMGILLLSLLLSSWLYWGSDFKLEQVLTSREWQSKMVSLIKTNSNRPAMGPLSRVDVTSNVKYLPNGTYLRVSIVKLFSDDNSAESVINISEFGEWDISDNYLLVTPVEFKDISSNQSKDFTDEQLQLITQLFKMDAQQSRRVDIVNERTILFTSLSHGSTVLFSNS
What is the function of this protein?
Interacts with ToxR and stimulates its activity.
What are the official names of this protein?
Transmembrane regulatory protein ToxS.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein; Periplasmic side.
Protein: SLIRP_HUMAN
Sequence: MAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVKVQVHTRRPKLPQTSDDEKKDF
What is the function of this protein?
RNA-binding protein that acts as a nuclear receptor corepressor.  Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation.  Binds the STR7 loop of SRA RNA.  Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.
What are the official names of this protein?
SRA stem-loop-interacting RNA-binding protein, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus. Note=Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters.
Protein: RL35_XANCP
Sequence: MPKIKTNRAAAKRFRKTASGKYKCGHANRSHILTKKATKRKRNLRQTNHVRAEDAGRLDRMLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GTX3A_NEOAP
Sequence: GFKDWMKKAGSWLKKKGPALIKAAMQE
What is the function of this protein?
Has activity against some Gram-positive bacteria and S. cerevisiae.  Has a non-hemolytic activity.
What are the official names of this protein?
U1-poneritoxin-Na3a, U1-PONTX-Na3a, Poneratoxin, Ponericin Pa I1.
What is the protein family that this protein belongs to?
Belongs to the ponericin-G family.
What are the subcellular locations of this protein?
Secreted.
Protein: SOMA_TRITC
Sequence: MDKVLFLLFVLSLGVSSQPITDSQRLFSIAVSRVQHLHLLAQRLFTDFESSLQIEEQRQLNKIFLQDFCNSDYIISPIDKHETQRSSVLKLLSISYRLIESWEFPSRSLYGGSAQRYQISPKLSELMRGIQLLIKANQDGAEMFSDGVVPQLAPYGNYYQSLGEDESLRRSYELLACFKKDMHKVETYLTVAKCRLSPEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HMCS2_BOVIN
Sequence: MQRLLTPVRQVLQVKRVMQEASLLPARLLPAAHPSFSTVPAVPLAKTDTWPKDVGILAMEVYFPAQYVDQTELEKFNKVEAGRYTVGLGQTQMGFCSVQEDVNSLCLTVVQQLMERTQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLRGTHMENVYDFYKPDVTSEYPLVDGKLSIQCYLRALDKCYAFYRQKIEKQWKQAGIDRPFTLDDVQYMIFHTPFCKLVQKSLARLMFNDFLLASGDTQTGIYKGLEAFRGLKLEDTYTNKDVDKAFLKASLNMFNKKTKNSLYLSTYNGNMYTSSLYGCLASLLAHHSAQDLAGSRIGAFSYGSGLAASFFSFRVSQDASPGSPLEKLVSSTSDLQKRLASRKRVSPEEFTEIMNQREQYYHKMNFSPPGDKNSLFPGTWYLERVDELYRRKYARRPV
What is the function of this protein?
Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.
What are the official names of this protein?
Hydroxymethylglutaryl-CoA synthase, mitochondrial, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GLMU_CARHZ
Sequence: MEGIILAAGKGTRMKSDLPKVVHEVAEKPMVLRVYEALVGAGVKRVVAVVGYRKEKVEEILRGRAVIAVQEEQLGTGHAALVAMPYVEDENVIIVPGDTPLLKASTLQALIKKHLETGAYATVLTCFLSNPYGYGRIVRDGYGKIIKIVEEKDATLEEKQIAEVNTGIYCFNTKILKEILPLLKAENAQKEYYLTDVIPLLLERGKVVETITIQDETEVYGVNDRVQLARLTKGVYRRKAEALMQEGVTIIDPETVYIGEEVVVGSDTVIYPNTYLEGKTVIGSGCRLGPNTRITDSVIGNNTEITFSVIIQARVGDEVNVGPFAYLRPGTEIANGVKIGDFVEIKKSFIGEGSKVPHLSYIGDAVVGKGVNIGAGTITCNYDGKNKWETVIEDGAFIGSNTNLVAPIKIGKNAVVGAGSTLTEDVPEKALAIARSRQVNKEDYVK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_STRPJ
Sequence: MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVKRKRKSEVARKRKKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DEOD_CLOTE
Sequence: MSIHINAPEGAIAESILLPGDPLRAKFIADTFLEDVVCYNEVRGMYGFTGTYKGKRVSVQGTGMGIPSMSIYATELIESYGVKNLIRVGTCGSYVEKVKVRDLIIAMSACTNSNINLVPFKGRTFAPTASFDLLKPAYDIAVEKGFEPKVGSIYSSDIFYDDDKEDWKTWAKYGCLGVEMETAALYTIAAKYGVNALTLLTVSDHFVTHEVTSAEERQTTFKAMMEVALDTIVNL
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: TYPH_ECOLI
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENNWQEAAKAVKAAIKLADKAPESTPTVYRRISE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: FRDD_SALHS
Sequence: MINPNPKRSDEPVFWGLFGAGGMWGAIIAPVIVLLVGIMLPLGLFPGDALSFERVLTFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTAIGVITL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECB_XYLFT
Sequence: MSDEITNGAAKPTEAISGPTFTIEKIYIKDVSFEAPNSPAVFNEAGQPELQLNLNQRVQRLNENAFELVLHVTLTCTAAGKTAYVVEVQQAGVFGLFGLDQHAIGVLLGTQCPNILFPYVRSLVSDLIQIGGFPPFYLQPINFDALYAETLRQRAQNEKEGSQISSQPAGNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S10A8_MOUSE
Sequence: MPSELEKALSNLIDVYHNYSNIQGNHHALYKNDFKKMVTTECPQFVQNINIENLFRELDINSDNAINFEEFLAMVIKVGVASHKDSHKE
What is the function of this protein?
(Microbial infection) Upon infection by murine coronavirus (MHV-A59), induces expansion of aberrant immature neutrophils in a TLR4-dependent manner.
What are the official names of this protein?
Protein S100-A8, Calgranulin-A, Chemotactic cytokine CP-10, Leukocyte L1 complex light chain, Migration inhibitory factor-related protein 8, MRP-8, p8, Pro-inflammatory S100 cytokine, S100 calcium-binding protein A8.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Note=Predominantly localized in the cytoplasm. Upon elevation of the intracellular calcium level, translocated from the cytoplasm to the cytoskeleton and the cell membrane. Upon neutrophil activation or endothelial adhesion of monocytes, is secreted via a microtubule- mediated, alternative pathway.
Protein: AROB_PROM5
Sequence: MNKNKIIVPLSNNSYEVTIRQGIINSIGKELTQIGINNNRKILIVSNKEISNLFGSKLLNDLKKYNFSAEIFNIKAGESYKNLASLREIYDAAFEFGLDRNALLIALGGGIVGDVTGFAAATWLRGIDYIQIPTTLLSMVDSSVGGKTAVNHPKGKNLIGAFYQPKAVFIDPETLKTLPIREFKAGMAEVIKYGVIKDKELFEYLEIDKNREKILNLDNESLIKIINKSIRTKSYIVSKDEKENGIRAILNYGHSFGHVIENLCGYGEYLHGEAISIGMKIAGDISTEKNLWLKEDSLRQDKLIESYGLPTQTPKIKKHDVITILMGDKKVRDGKMRFILPKGIGEVDIFNDIKESQFLKYFD
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATD_DEIRA
Sequence: MAGQISPTRSALLASKASLKTANGGADLLKRKRDALIGEFFALVKDALAAREQLSSVSKGAYTSLFGAKAWDSPEAVESLSLAGTGDYAVDMQIESIYGVKVPKINIPERAAQADFSPINVGARTIQASNDFGGVLEAIVKVAATETKLRRIGEEIKKTSRRVNALEQVVIPGIHDDIRFIRSVLDQREREAGYTQKKIKAKIEGKNKEAREAAAATSHGSAAD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: CYNS_PSEE4
Sequence: MIQSQISQNARLALSEVILLAKARKDLSFAQITEGTGLSEAFVTAALLGQHPLPASAAQVVGDKLGLDADGIALLQTIPLRGSIQGGVPTDPTIYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVDDPEGGSRAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: KTAP2_IXOSC
Sequence: MAVSSGTSGMLATCLFMLLFATMQIYKSQLTSSQPMAIVGGFLGSVLFILILTAISNFETHFFGRNFQTKLIPEVVIALVIAMAASGMVHRVCITTCLIFSIVALYYVSRISIKVHGSGAGTATAIPVTKGKKGK
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Protein KRTCAP2 homolog, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2, Oligosaccharyl transferase subunit KCP2.
What is the protein family that this protein belongs to?
Belongs to the KRTCAP2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL5_NANEQ
Sequence: MEHPMRKIRIEKVTLNIGVGESGEKLDKAYELLKRLTGQKPVKTKAKVRVEQWHIRPGLPIGVKVTLRGEKAYKILKEKLLPAVDFKIKASSFTDRGFGFGIPEYIMIPGMKYDPELGLIGLEAYVTLERPGYRVERRRIKRSKVGSRHRLNKEEIIKWAQEELGVQII
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NHAA1_KLEP7
Sequence: MKVKVKHLQRFFSSDASGGIVLIIAAALAMVMANTSVTSGLYHSFLETPVQLRVGALEINKNMLLWINDALMAVFFLLIGLEVKRELIQGSLASRRQAVFPVIAALGGMIVPALVYLAFNAQDPVAREGWAIPAATDIAFALGVLALLGSRVPTALKIFLMALAIIDDLGAIVIIALFYTHDLSMLSLGVAAAAIAVLMALNLSGVRRTGIYILVGAVLWTAVLKSGVHATLAGVIVGFMIPLEEKHGKSPAKALEHVLHPWVAFMILPLFAFANAGVSLQGVTLAGLTSLLPLGIMAGLFIGKPLGISLFCWLALKLKWASLPEGTTCKQIMAVGILCGIGFTMSIFIATLAFGSVDPALINWAKLGILIGSVLSAVVGYLILRQRVTDTRLAV
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRE_STRT1
Sequence: MTLASQIASDLLDIKAVYLKPEEPFTWASGIKSPIYTDNRITLSYPETRTLIENGFVKKIKEEFPEVEVIAGTATAGIPHGAIIADKMNLPFAYIRSKPKDHGAGNQIEGRVVKGEKMVVVEDLISTGGSVLDAVAAAEREGADVIGVVAIFTYELPKAEKNFAEAGVKLVTLSNYTELIKVAKVKGYITADGLRLLKKFKENQETWQD
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.