PharMolix/UniProtQA huggingface dataset:
Protein: CCNB_MARGL
Sequence: MLNGENVDSRIMGKVATRASSKGVKSTLGTRGALENISNVARNNLQAGAKKELVKAKRGMTKSKATSSLQSVMGLNVEPMEKAKPQSPEPMDMSEINSALEAFSQNLLEGVEDIDKNDFDNPQLCSEFVNDIYQYMRKLEREFKVRTDYMTIQEITERMRSILIDWLVQVHLRFHLLQETLFLTIQILDRYLEVQPVSKNKLQLVGVTSMLIAAKYEEMYPPEIGDFVYITDNAYTKAQIRSMECNILRRLDFSLGKPLCIHFLRRNSKAGGVDGQKHTMAKYLMELTLPEYAFVPYDPSEIAAAALCLSSKILEPDMEWGTTLVHYSAYSEDHLMPIVQKMALVLKNAPTAKFQAVRKKYSSAKFMNVSTISALTSSTVMDLADQMC
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: RNH2_VIBA3
Sequence: MAVKEKKEFPPFEYPQGYQLFAGVDEVGRGPLVGDVVTAAVILDPNNPIEGLNDSKKLSEKKRLALLPEIKEKALAWSVGRCSPQEIDELNILQATMVAMQRAIAGLSVQPDMALIDGNRVPELPMAGLAIVKGDLRVAEISAASIIAKVVRDQEMEELDKLHPEFGFAKHKGYPTKAHFEAIEKHGVTEHYRKSFKPVKRILGID
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_BURP6
Sequence: MHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTYENIAYMKKQMQSMGLAIDWSREVTTCKPDYYKWNQWLFLKMLEKGVAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYMRITQYADELLNDLDGLGWPERVKVMQHNWIGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLARDKPALQAFIDECKRGGVAEADIATMEKKGVATGFSVSHPLTGEPVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTRAVCVNSGKYDGLAHDAAVDAIAAELKAGGLGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDLVPDGTGNPLAKSDAFLNCTCPKCGAAAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYREDAAGKKTWYNPADVTVSFDDKGRPVGAVLKSDGQPVELGGIEKMSKSKNNGVDPQMLIDHYGADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDAAQLAEADKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRVLYPVVPHVTFELWKALGYADEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKDASREAIEAAAVADEMFAKFAEGRPAKKIIVVPGRLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C19AA_BACTJ
Sequence: MHYYGNRNEYDILNASSNDSNMSNTYPRYPLANPQQDLMQNTNYKDWLNVCEGYHIENPREASVRAGLGKGLGIVSTIVGFFGGSIILDTIGLFYQISELLWPEDDTQQYTWQDIMNHVEDLIDKRITEVIRGNAIRTLADLQGKVDDYNNWLKKWKDDPKSTGNLSTLVTKFTALDSDFNGAIRTVNNQGSPGYELLLLPVYAQIANLHLLLLRDAQIYGDKWWSARANARDNYYQIQLEKTKEYTEYCINWYNKGLNDFRTAGQWVNFNRYRREMTLTVLDIISMFPIYDARLYPTEVKTELTREIYSDVINGEIYGLMTPYFSFEKAESLYTRAPHLFTWLKGFRFVTNSISYWTFLSGGQNKYSYTNNSSINEGSFRGQDTDYGGTSSTINIPSNSYVYNLWTENYEYIYPWGDPVNITKMNFSVTDNNSSKELIYGAHRTNKPVVRTDFDFLTNKEGTELAKYNDYNHILSYMLINGETFGQKRHGYSFAFTHSSVDPNNTIAANKITQIPVVKASSINGSISIEKGPGFTGGDLVKMRADSGLTMRFKAELLDKKYRVRIRYKCNYSSKLILRKWKGEGYIQQQIHNISPTYGAFSYLESFTITTTENIFDLTMEVTYPYGRQFVEDIPSLILDKIEFLPTN
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of mosquitos.
What are the official names of this protein?
Pesticidal crystal protein Cry19Aa, 75 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryXIXA(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: NUOB_LEPBL
Sequence: MGLSDLSKAPGQALGDMLQLGNIESVIQWGRGNSLWPFPFATACCGIEYMSTACSDYDIARFGAERPSFSPRQADMILVLGTITYKMAPVLRQIYDQMAEPKFVISVGACASSGGMFNTYGVLQGVDRILPVDIYVPGCPPRPEAILDALVKLQTKLKTQGLEARRQEVMQKIQELNERNKPLVVR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: M1249_ASFWA
Sequence: MEEVITIAQIVHRGTDILSLNNEEIEALVDEIYSTLKGSNDIKNIRLIDFLFTLKDFVNHVRAEQSKLPDLSMPMEAYIRQLLVDSDVVPIVSEKKKELRVRPSTRKEIFLINGTHLAVPAEAPIEIYGLKLRLKTFSPQCFMRMAEIGSFSPETLGYVASGANLTNFIRVFMKCVDQETWKKNGEGVVVTTKENIIQFTHQYIELYKFLRSGGHSWLINRLAEEMVHRKLDREDQGSHISNIVETEEIEPEENIKRVIFFLKELSTMYSVSPVFTSGYMPLLYDLYRAGYLEVLWNPVEQKFLQHAEQREKEQMILQQVDMKLMEVTTQARQYFKIMEEKIGRVQSDAIREILTMEGKVDDPNSILQEVIKACGKQEAELITTEYLNIKKQWELQEKNACAHLKLVKQLRSGLQYAESLKVLESIRVLYKEKNNTTNWNLCKACGFKLLCPHVDMLIQLQAAEASYDTMRTKLMKFSGINKEKENNQGLIYSYFCKICGEELAHFIQEDRTADVGVIGDLNSKLRIFIWQETMKACTFIHFGKLVDVKQFANIAVNVCLPLVYSIENIKKEEDYDPLTQLYAVIYIYAYILNLIYSSQKNKEFLTITIHGMKADSSLNAYVTFLLEKMMQQYSGIINQLSEITDQWIANNFREAFKKIIHQNGLQGLSVQDDTKVLLTEILLDPMYDYAATVARIDGSIPMHKPRTPKEAEYEFKTVIGRTPAELLSQKEFYDKIYTSKYRPDFTQLARLKDIYFQEESLRVWWGGRDEEKTSTLIYLRAYELFLKYLQNAPNFNSELAEFKTYENAYGEQKALLAQQGFYNIFDPNTGRADQRTRLFEYKRLPISTLYDERGLPHKWTIYVYKAVDSSQKPTEIEVTRKDVIKKIDNHYALADLRCSVCHVLQHEVGQLNIKKVQTALKASLEFNTFYAFYESRCPKGGLHDFQDKKCVKCGLFTYIIYDHLSQPELVHDYYNNYKDQYDKEKMSIRSIQIKKDMTMPSTETQPKPPQEPWTFDYGKIIKTAKILDISPAVIEAIGAMEGRSYADIREGQGAPPPPTSMDDPRLMAVDSAVRIFLYNYNCLRHVSTFNKPPMHVERLVKHLSYEEKEDLEKVLPNVVNEYHTTFKHLRVTDPASALLYSIEFLCISFLTLYDIKEPSWVVNIVREFALTELNTIIQSEKLLSKPGAFNFMIFGEDFVCSGEDSSMDDISAYSSPGLFGEDIIDRLDDPFSIEDVDISLDVLDNLAPQ
What is the function of this protein?
Together with the penton and the other minor capsid proteins (p17, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid.  In addition, blocks IFN-beta transactivation mediated by the cGAS-STING pathway and regulates the transcriptional activity of IFN-beta.  Mechanistically, suppresses the phosphorylation of host key adapter protein TBK1 and degrades host IRF3 in the cyltoplasm.
What are the official names of this protein?
Minor capsid protein M1249L, pM1249L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus M1249L family.
What are the subcellular locations of this protein?
Virion.
Protein: ATPE_STRA5
Sequence: MAQLTVQVVTPDGIRYDHHASLITVRTPDGEMGILPGHINLIAPLNVHQMKINRSHQEGVDWVAVNGGIIEVNEDQVTIVADSAERARDIDLNRAERAKERAERALEKAQTTQNIDEMRRAEVALRRAINRISVGKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MIAB_PARDP
Sequence: MSDQASKPAPAVKKLFIKTYGCQMNVYDSQRMAEAMGAEGYVLTENQSDADMVLLNTCHIREKAAEKLYSDLGRLKPLKAERPDLKIGVAGCVAQAEGEEIQRRMPIVDLVVGPQAYHRLPAMARAGRGVDTEFPAEDKFEHLPKPAATRRAPAAFLTVQEGCDKFCAFCVVPYTRGAEVSRPVSRILAEARDLVARGVREITLLGQNVNGWHGEGPEGSEWGFGRLIRAIAEIDGLDRIRYTTSHPNDMADDLIAAHRDEPKLMPYLHLPVQSGSDRILKAMNRRHTVDQYLRLIERIREARPDIMLTSDFIVGFPGETDQDHQGTLELVRAVNFGTAFSFKYSPRPGTPAYERPEIEGAVADARLQELQALLTSQQKAAQEGMVGRELGVLFEKPGRNPGQMVGKSDYLHAVFVEAPAAKVGDLVRVRITHSAPNSLAGVLAA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_LYSSC
Sequence: MFDRLQAVEDRYERLTELLSDPDIVNDSKKLREYSKEQSDIQETVDTYREYKNVKEQLVDTREMLDSEKDPDMHEMVKEEFNLLKAQQEELEERLRILLIPKDPNDNKNVIMEIRGAAGGDEANIFAGDLFRMYSRYAETQGWKIDIMEATPNPMGGYKEVIFMINGQGAYSKFKFENGAHRVQRVPATESQGRIHTSTATVACLPEVEEVDVEIHEKDIRVDTFASSGAGGQSVNTTMSAVRMTHLPTGVVVSMQDERSQIKNREKAMKILRARVADMYMQEAQKEIDATRKSAVGSGDRSERIRTYNYPQNRVTDHRIGLTIQKLDQIVEGRLDEIIDTLILEEQASKLERLNDDL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_CAMSC
Sequence: LHMIHLHWYQYPPMNPMMYPLLLIFMFITGIPCLAGNFVTIWVFMTTKSLRSPANLLVVNLAMSDFLMMFTMFPPMMITCYYHTWTLGPTFCQVYAFLGNLFGCTSIWTMVFITFDRYNVIVKGVAGEPLSNKKAALWILSAWVLSFSWCSAPFFGWNRYVPEGNLTGCGTDYLSEDALSRSYLYVYSVWVYFLPLLITIYCYVFIIKAVAAHEKGMRDQAKKMGIKSLRNEEAQKTSAECRLAKIAMTTVALWFIAWTPYLLINWVGMFARSYLSPVYTIWGYVFAKANAVYNPIVYAIS
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Can use both retinal and 3-dehydroretinal as visual pigment.  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Signaling via GNAQ probably mediates the activation of phospholipase C.
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Detected on the rhabdomere membrane in the photoreceptor outer segment.
Protein: HIS7_HALSA
Sequence: MTDRTAAVTRETAETDVAVTLDLDGDGEHTVDTGIGFFDHMLAAFAKHGLFDVTVRCDGDLDVDDHHTVEDVGIALGAAFSEAVGEKRGIQRFADRRVPLDEAVASVVVDVSGRAVYEFDGGFSQPTVGGLTSRMAAHFWRTFATHAAVTLHCGVDGENAHHEIEALFKGVGRAVDDATRIDQRRAGETPSTKGDL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU2_STRAW
Sequence: MPKTAYVRTKPHLNIGTMGHVDHGKTTLTAAITKVLAERGSGTFVPFDRIDRAPEEAARGITINIAHVEYETDTRHYAHVDMPGHADYVKNMVTGAAQLDGAILVVSALDGIMPQTAEHVLLARQVGVDHIVVALNKADAGDEELTDLVELEVRELLTAHGYGGDSVPVVRVSGLKALEGDPRWTAAIDALLDAVDTYVPMPERYVDAPFLLPVENVLTITGRGTVVTGAVERGTIRVGDRVDVLGASVETVVTGLETFGKPMEEAQAGDNVALLLRGVPRDAVRRGHIVAAPGSVVPSRRFSARVYVLSTREGGRTTPVATGYRPQFYIRTADVVGDVDLGETAVARPGDTVTMTVSLGRDVPLEPGLGFAIREGGRTVGAGTVTTVED
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPYA_TRITO
Sequence: MKFLTTGLLATAALAAAQEQQVLQAEDGMGQAPQRGSSIFDETLQKFQSSLEDGISHFWSEMKTNFKDYLPLISLPKKHTRRPDSEWDHVVRGADIESVWVQGADGEKRREIDGKLHNYDLRVKAVDPSKLGVDAGVKQYSGYLDDNDADKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPATIDKNLKVVSNPYSWNSNASVIFLDQPVNVGFSYSGSSVSDTVAAGKDIYALLTLFFKQFPEYATQDFHISGESYAGHYIPVFAAEILSHKNTNINLKSALIGNGLTDPLTQYPQYRPMACGEGGYPAVLDQGTCRSMDNSLERCLSLIETCYSSESAWICVPAAMYCNSAILAPYQQTGMNPYDVRNKCEDMASLCYPQLNVITEWLNQKSVMQALGVEVESYESCNSGINRDFLFHGDWMKPYHRLVPSVLEKIPVLIYAGDADFICNWLGNQAWTDALEWPGHKKFAEAKLEDLKIVDNKNKGKKIGQVKSSGNFTFMRIFGAGHMVPLNQPEASLEFLNRWLRGEWH
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: NU4M_CROOO
Sequence: PIAGSMVLAAILLKLGGYGIIRMMQIFPTTKTDLFLPFIVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGFHNILPMTTTWWLMTNLMNIAIPPSMNFTGELLIMSALFNWCPATIIMLGLSMLITASYSLHMFLSTQMGPTLLNSQTEPMHSREHLLITLHLAPLLMISLKPELVI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PHEB_MICDP
Sequence: MLDAFSRAVVSADASTSTVSDIAALRAFVASGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIVLRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIQDTPSEARAGAKLRKMGTPVVEDRCASLVAEASSYFDRVISALS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
C-phycoerythrin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the periphery of the phycobilisome rod.
Protein: LAP1_PYRTR
Sequence: MKSAALLLPLYTAAFAAAAFHHEHAQAVIQDQQLTIVEPDEYLIELSPGETRWVNENEKWELRKKNINFFDITHNAELGTLNHRINAESVKYPSKPVFNETLAPLLKELDKNNMRAHLETFTSFHTRYYKSQYGVQSSAWLLGQVNKTLADAGAINASVKAFPHPWGQSSIIATIPGKSDKTIVIGAHQDSINLFFPAFLAAPGADDDGSGTVTILEALRVLLKSDEILKGEAENTIEFHWYSAEEGGLLGSQAIFQSYEKEARDVKAMLQQDMTGYVQKTLDAGEPESVGVITDFVDPGLTEFIKKIITVYCDIPYVLTKCGYACSDHASASKAGYPSAFVIESDFKYSDKKIHTTEDKIEYLSFDHMLQHARMTLALAYELAFAEFK
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YJBI_ECOLI
Sequence: MKKIECACNFLMDKDAQGYIDLSDLDLTSCHFKGDVISKVSFLSSNLQHVTFECKEIGDCNFTTAIVDNVIFRCRRLHNVIFIKASGECVDFSKNILDTVDFSQSQLGHSNFRECQIRNSNFDNCYLYASHFTRAEFLSAKEISFIKSNLTAVMFDYVRMSTGNFKDCITEQLELTIDYSDIFWNEDLDGYINNIIKMIDTLPDNAMILKSVLAVKLVMQLKILNIVNKNFIENMKKIFSHCPYIKDPIIRSYIHSDEDNKFDDFMRQHRFSEVNFDTQQMIDFINRFNTNKWLIDKNNNFFIQLIDQALRSTDDMIKANVWHLYKEWIRSDDVSPIFIETEDNLRTFNTNELTRNDNIFILFSSVDDGPVMVVSSQRLHDMLNPTKDTNWNSTYIYKSRHEMLPVNLTQETLFSSKSHGKYALFPIFTASWRAHRIMNKGV
What are the official names of this protein?
Putative protein YjbI.
Protein: SLB8_MACLB
Sequence: DCPWDWSSHEGHCYKVFKFATTWEDAEKFCTEQARGGHLISIKSTEEVDFMIKLAYPILKANLVWIGLRVEDFWRDCHMGWRDHANLLSKPGVVHNTKCFGLDQKTGYRTWVALRCELAYHFICMSRVPR
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec B8, C-type lectin B8.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROCN_OLEEU
Sequence: MSWQAYVDEHLMCEIEGHHLTSAAIVGHDGAVWAQSTAFPQFKTEEMTNIMKDFDEPGFLAPTGLFLGPTKYMVIQGEPGAVIRGKKGSGGITVKKTGQAMVVGIYDEPMTPGQCNMVVERLGDYLLNRA
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-9, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ZAPD_CROS8
Sequence: MQTHVLFEHPLNEKMRTWLRIEFLIQQMKALLPVSDHASALHFFRNVGDLLDVFERGDTRTELLKELERQQRKLQSWAEVPGVDNERIESLRHELKARSSMLMAAPRLGQTLREDRLIALVRQRLSIPGGCCSFDLPLLHVWLCSPQEERDVQVNSWLATLQPLTYTLDMILDLIRQSAPFRKQTSLNGFYQDNGDDADLLRLQLPLQEALYPQISGHKSRFAIRFMPLDSEHGRVPERFDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: LEXA_CORJK
Sequence: MSIDESSDNPTPRPKLGRPPKSEADKRAEKEAQKDGKKPALSTRQRRILEVIRDSTIIRGYPPSIREIADAVGLHSTSSVSYHLTQLEKRGYLRRDGKRPRAVDVRAFDGGQLTNESTKKNAGSPQPTSAAIPEPTTEGETMPEATYVPVVGQIAAGAPILAEQNVEAHFPLPQELVGNGELFLLQVVGESMHDAGIFNGDWVVVRSQSVAEFGDFVAAMIDGEATVKEFQKDADGLWLIPHNPLFEPIPAEEATILGKVAAVLRKI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CP51A_RAT
Sequence: MVLLGLLQSGGSVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPYIYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAVFLEQKKILKSGLNIAHFKQYVSIIEKEAKEYFKSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDSTYKDGRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGEDLPPLTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLINGYFPSVNYTTMIHTPENPVIRYKRRSK
What is the function of this protein?
Sterol 14alpha-demethylase that plays a critical role in the cholesterol biosynthesis pathway, being cholesterol the major sterol component in mammalian membranes as well as a precursor for bile acid and steroid hormone synthesis (PubMed:7665087, PubMed:10544287).  Cytochrome P450 monooxygenase that catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of sterols such as lanosterol (lanosta-8,24-dien-3beta-ol) and 24,25-dihydrolanosterol (DHL) in the form of formate, and converts the sterols to 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol and 4,4-dimethyl-8,14-cholestadien-3beta-ol, respectively, which are intermediates of cholesterol biosynthesis (PubMed:7665087, PubMed:10544287, PubMed:11328599, PubMed:3782148, PubMed:1872829).  Can also demethylate susbtrates not intrinsic to mammals, such as eburicol (24-methylene-24,25-dihydrolanosterol), but at a lower rate than DHL (PubMed:1872829).
What are the official names of this protein?
Lanosterol 14-alpha demethylase, LDM, CYPLI, Cytochrome P450 51A1, CYP51, Cytochrome P450-14DM, Cytochrome P45014DM, Cytochrome P450LI, Sterol 14-alpha demethylase P450.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single- pass membrane protein.
Protein: DF182_ARATH
Sequence: METVTSLVFIVNLLIIFTSVVNQARGDTCIDGLGYCNNCDERCKAKHGPSSESSCDRSVGVPLCKCYYECESPPSPPAPPKKCDGGAGICSQRCQGQCCDMNCAQKYIGGHGFCNTLGTFSFCQCEYPC
What is the function of this protein?
Confers broad-spectrum resistance to pathogens.
What are the official names of this protein?
Defensin-like protein 182, Low-molecular-weight cysteine-rich protein 59, Protein LCR59, Plant defensin 3.2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: FUT1_SAPAP
Sequence: MWPLSHRHLCLAFLLVCVLSAISFFLHIHQDSIRHGLGLSVLCPDRHLVTPPVAIFCLPGTPMSPNTSSPCPQHPASLSGTWTIYPDGRFGNQMGQYATLLALAQLNGRRAFILPAMHATLAPVFRITLPVLAPEVDSRTPWQELRLHDWMSEEYADLGDPFLKLSGFPCSWTFFHHLREQIRSEFTLHDHLREEAQSVLRRLRLGRSGDRPRTFVGVHVRRGDYLQVMPQRWKGVVANSAYLREAMDWFRARHEAPVFVVTSNGMEWCRENIDTSKGDVMFAGDGQEASPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEFLKIFKPEAAFLPEWVGINADLSPLWTLAEP
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens.  H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis (By similarity).  Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a (By similarity).
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 1, Alpha(1,2)FT 1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: RL3_HALWD
Sequence: MPQPSRPRKGSMGFSPRKRAESEVPRIRSWASNDGAPGVQGFAGYKAGMTQVLMVNDEANSPREGMEEAVPVTVVETPPMRAVALRAYEDTPYGSKPLTEVWGREFDTSLERTLDLPNEDTFEDDAAALRDDAETGDIDDVRLITHTLPAGMRNIPKKTPDVMETRVGGGTLTDRVEFGLDLISDGGEHEISDIFRAGEYLDAAGVTKGKGTQGPVKRFGVQKRKGKHARQGYRRRIGNLGPWNPSRVRSTVPQQGQTGYHQRTELNKRLIEIGNGDEPTVDGGFVGYGEVDGPYALIKGSLPGPDQRLLRFRTAVRPSDQPRLDPEVRYVSTASNQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RBSD_THEP3
Sequence: MKKTYLLNSEISEVVARLGHTDLLVIADSGLPIPDGVKRIDIALTKGIPSFKDTLNTVLTELGVEKAYIAKEMIDKNNDLYLYLLELFGEKLIIISHEDLKAMSKNARAIIRTGEYKPYANIILESGVEF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.