PharMolix/UniProtQA huggingface dataset:
Protein: CABIN_HUMAN
Sequence: MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
What is the function of this protein?
May be required for replication-independent chromatin assembly.  May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin.  Inhibition of activated calcineurin is dependent on both PKC and calcium signals.  Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes.
What are the official names of this protein?
Calcineurin-binding protein cabin-1, Calcineurin inhibitor, CAIN.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATA_SACS2
Sequence: MNRIMIVDLVNDLRNKNLEAEEYIERTYEKIGKYDKYINAFITIRSKEEVLKEVKESINKGGKLAGVLIAIKDNISTEGIRTTCASKMLEDYIPPYDATVIEKLKKEGAVIIGKTNMDEFAMGSTTETSYFGPTRNPWDLERTPGGSSGGSGAALAAGYVELALGSDTGGSIRAPAAYNAIFGLKPSYGTVSRFGLVAYANSLEQIGPMARNAEDLGLLFSIIAGPDERDATTINLNLNFELKERSVKNVRIGVLSDILEMSEKPVSGVIKDVVNKLSSEGALIEDTKLGNAEYALPAYYIIAMSEASSNLARYDGVRYGYSKYMEGNWREVYAKNRGEAFGMEVKRRILLGSFILSAGYYEEFYLKALKVRNLIKKNLDELFKKYDILLSPTMPILPPKIGEVINDPVRMYAMDLNTVIANLAAIPALSMPVGFYSDLPIGLQLMGKYLSDIYLINISSFIERNITKLYNLTASVKI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: VP35L_RAT
Sequence: MAVFPWHSRNRNYKAELASCRLETVPLECGDYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAATSDPAATVTVTESSRKKRDKDDNSFVGPDFEPWANKRGEILARYTTTEKLSINLFMGSEKGRAGAAASAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIYSMCVDSRGALPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKESLTRNFFDFLLTFKQIHGDTVQNQLVAQGVELLSYLPLYSPAMGWIFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGVNLALADPPENDRLQILNEAWKVITKLKSPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFINALTLEDEKRMLAHLINGFIKMVSFGRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKSISIDGKLRPSEPFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVIQDYTWEDSSDDKIRIYTSVLHLLSAMSQDTYLYHIDKVDSNDSLYGGDSRFLAENSKLCEAAMVQILEHLKTLAKDEALKRQSLLGLSFFNSILAHGDLRNNKLNQLSVNLWHLAQRHGCADTRTMVKTLDYIKKRSKQPDMNHLSELALRLPLQTRT
What is the function of this protein?
Acts as component of the retriever complex.  The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1).  The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes.  In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.  Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association with the CCC complex and cooperation with the WASH complex on early endosomes.  Seems not to be required for CCC complex stability.
What are the official names of this protein?
VPS35 endosomal protein-sorting factor-like.
What is the protein family that this protein belongs to?
Belongs to the VPS35L family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Endosome. Note=Endosome location is dependent of the association with the CCC and WASH complexes.
Protein: CCD54_MOUSE
Sequence: MYRFHTKRVRAAAGQVWTANLHKIRRSLKNVYQKCTTHHSYSTSYPTRASYGCDGDTLSLNEDMNLPAMLQDIKTGQTELLNQMTNIVSSISNIQEKINHYQNQMEALEARINISEDRQTATTKDMLSMKEDINTLKKKVTELESQNSYSSIHCLEVLEGQRGKEFVQLLHKLLQTETPKGTATSPDTVISSAEPERVSSYPEPTGELKKKTTSPQNITLKKNNSLQNASVGCKKVRSNIYIYPDFSTWIKLTFVHGGNWRFFLSATKLEEFIQWLLSRSTILPEEPQIIPQRDYAFTGAIGRLATICLSLFHYVYCLFGSSKEEITRL
What are the official names of this protein?
Coiled-coil domain-containing protein 54.
Protein: CAF20_CANGA
Sequence: MIKYSIDELIQLKPSETLKVSFDHVEFRNIIEKVVELQKLKEEEFHSHHGNRRRSSHHHMKPKIKHNKPKVKTDADGWSTLEPATAGHEEESSSSATPAAAATTKTGAPQETIRVKPNNKNISSSRPADNSDIIADKQTHGFNAFAALEDEEDE
What is the function of this protein?
Acts as an inhibitor of cap-dependent translation.  Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA (By similarity).
What are the official names of this protein?
Cap-associated protein CAF20.
What is the protein family that this protein belongs to?
Belongs to the CAF20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_RICB8
Sequence: MKKNPKISLIGSGNIGGMLAHLISLKNLGDIVLFDVAEGIPQGKALDIMQANTLAGSDIKIKGTNDYKDIEGSDAIIITAGLPRKPGMSRDDLISVNTGIMKSVAENVKKYAPNAFVIVITNPLDVMVYVMLKESGLPHNKVIGMAGVLDSSRFNFFLAEEFKVSTNSVSSIVLGGHGDAMVPLARYSTVKGVPIPDLVKMGLSTNERIEKIIDRTRNGGGEIVALLKTGSAYYAPAASAVEMLESYLQDKRQILTCAAYLQGEYGVKDLYAGVPIIIGKNGVEKVIELQLTTNEQALFDKSVDGVRKLIEAVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: RHAM_ECO7I
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWLELEAVLKSHGAHNYAIYLDKARNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM54_YARLI
Sequence: MADETAPKSSKPTAEAAPKKTGYTNPALRAMGIRQLRLPSRNWMIFWTVVGTISGGIYYDRHERKKVRQQYKDAVAYLGERPLGGLEIPRKITVFVAPPPGDYLDHVLTHFRAYIKPILTAAALDFEVKQESRQGEIRYVVAEGIRNYRREQMGLPKVPSRLMVDEEEYNKAVAEQNAEVERLKAGREKHTNPNPTFQAFNSINNRPGAPSSPDSQPEEQMSISVAGTIAQEQLDKEITSKLEFNPESGVICVGRGAYKEYLAGLHEGWLGPLEDPRPDEDNRKVYEEFPNREKDDDDALGLVKTPVEEPTTAVQNVQSVSEHLNSHPEMVKDVSETISHSGDVTAVTDVEQTAAGPVDVVSETASTHDTPAASDNKTPKPLSEMSPSEWDPKAPLPEIKRKPVPKPYIRPEEYSEAELSEFYASGFENASTAHSTVSSNINQQPNDLNSPAGSGTAFVEQFFFSPIAVIPHRHIMGFMNTPLRIARYFNKRAVADEVGAATVVAVTGDTRPFDVKTDPDLLVSEEYDWPSKWVKKGQDNGSEWVQPVVVDQRVMEKVKVYQPKGEGESELK
What is the function of this protein?
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM54.
What is the protein family that this protein belongs to?
Belongs to the TIM54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YGCC1_PLAF7
Sequence: MNFCDNNEMNETKNFMMSNKNDDIVVDCDEYIDGNVFEKNTNMGNIYDENYNVDMKNDNLLSKLNDNISFTYTTNGQVEKQENEIKEKQNILHYQIYIDNDEDKYKYCSNSNLHKNEEEHEKGSPNNIYEELDNNLEKKYFYYNSDSKHCIDEKNETNDLENENVVTSMDVSYENVLNDNFIKSRSTSINYTDNSFVLNKENLKSSHHINGYYINDHDNIKSDIINDHDNIKSDIINDYDNIKGDKINEYDNIKSDKINDYDNIKSDIINDYDNIKSDKINDYDNIKSDKINDYDNIKSDKINDYDNIKSDKINDYDNIKSDKINHYDNIKSDKINDYDNIKSDKINDYDNIKSDKINDYDNIKYNDDSQINNNVSNKVNSPDDDPNTYEKDKKDIINCNIYEENKNNMNNIIHNDKENIHMVDTGKNEENNNIDNKNNDDINKVNVLTRVDTENYILNEENILPLHTNDDVTKLLDEINDLKNTIENMKKEKINLLSKFKAYTLNNKKELEELKIKCKNKEEQIKMYENKLQNKEDEIMNYVNEIQNKDKKIESYHIKLHNKEEEIMNYVNEIQNKEEEIIKYVNELQNSDVQKEKKELKTINEVLKNTNEKLEKEITSLLGEMKKIEEENKVLKIFKEEKNKINNEKVTQIKGDDINDDNDMKFKQILLDNKTFNKLLVNELNIVEENILFCFSIDKDKNRLLVCIKQNDDNFFVIPNCIFDEKFPGLQKKTESMIIQDIHEKEILELKNKQMNELYILKKEKEDIYKEYEEYKKKVTSLINETNYNYKNIEEKENEIKELNNTLNKYKEEMNNYKEEIIVINEKYKLLEIELCKEKNIRDQQNVGISDLKKKMLKEKIELEKKYKEQYEKETQQKINDMKIIFDNKEKILQDQIDDLLHKIEKLTFSNDEKTKTIENLQIYMDNDDNIMNQEGIQKNEKKQIIDNPINTDEKDLLNYIPDNHINSDLNHINSNVENDYVEKRNKNNVHLSKKETNYQHNINEQENDNNNNNNNNNNNNNVEKLKSINSTNTSIPIYPYEYKKIRKKLETYEILLNEQQEGKKKMTEEINSLKNQVKNYESINGNYQHIIYQKNILSNFIAQIPSRIQVDDYVSVIFNSFNFSNQEIEAINIKRSKK
What are the official names of this protein?
GRIP and coiled-coil domain-containing protein.
Protein: LPXC_BRUSU
Sequence: MNAYQKTIGRAVTLSGVGVHGGAPASARLLPADADTGILFQRSDIKDSAPVCAHVSQIGATDLCTSLGAREARIDTVEHLMAAISALGIDNLVVEIEGPEVPILDGTSARFIEAVDSVGVVTQDAKRRFIRILKTVRVEAGNSWGEFRPYDGTRFEVEIDFECPLIGRQKFAHDVDEETFRKELSTARTFGFMKDVERLWAAGLALGASLDNSLVIGDDNSIVNADGLRFKDEFVRHKTLDAVGDLALAGLPFIGCFSSYRGGHRLNSEAVKALLSDETAFEIIEA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: NFUA_PSEAE
Sequence: MSAITITEAAQAYLAELLEKQSTPGIGIRIFITQPGTQYAETCIAYCKPGEEKVEDTAIALKDFTAWIDAVSEPFLEDAVVDYATDRMGGQLTIKAPNAKVPMVNEDSPITERINYYLQTEINPGLASHGGQVSLVDVVEDNIAVLRFGGGCQGCGMVDMTLKDGVEKTLIERIPELKGVRDVTDHSNKENAYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: Y2277_PSET1
Sequence: MPSFDIVSEVEMNEAKNAVDNANRELETRFDFRGVDASIELNDKVIKLKAEADSQVIQLFDILASKISKRGMDVSSLELQDISRAGKNVFRNVGLKQGIEKEMAKKIVKAIKDSKVKVQAAIQGEEVRVTGKKRDDLQEAMQVVRSADLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein PSHAa2277.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: NDHK_GOSHI
Sequence: MNSIEFPLLDRTTQNSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKISREIYEDRIRSQQGDRCFTTNHKFCLVRSTRTGNYNQGLLYQPPSTSEIPPETFFNYKGSLSSHELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: LIN59_CAEEL
Sequence: MHGAGEQQQRYRYNARSDEQHHHPSTSSHQYQQQGARQMHQMHPIQATLMCTPTTTSAAASTSSSGGSNSSGGSGGHRQQGNILRIGNSIKIGDNILEPAGTLVFSQADGTPWTGQRIVVNGSTHAVVKANLFPIGTTPPVLNMQSNQNWYMNQPSGTVPMSSNAPATTSSATPDSGIQSVPTSPPSPSYAMMNDVDIGDHDDEEDDDGPADFTDMPLLKPVDEDDDCYDVPCTSEGPPPNNSNPAITTIPSSCSTPAPPKESLPTGMNVEEWGSFLIASNMDREEIVRRLMAHDPEMAKAIAMRIRELSAEESKKKKDMEAEVSSTTPTTPRARGTRTRNKCATRSTNSPDVTTSNLPEEPSTSTMGLVKENEDVEKVEGKRRGRKPKKRRGFHKESFEDLESDAKKSKAEQHEDHLPEASCSSRPESVIPPPVDPIQFRLKVREMMERKLEQLTQKMSEDMTELRLSHLTSSKMVNGERGKRRESFLRQLNEQSKKLRKGGMLGRKRLRMFMTESDILEENKDNIKKEVKEESTPPPTKLRGRLPSRRTREPSEIVNPEPVEKKFNGEYFEITKSVPSSDDIIPLWMAPSLTCGCTKGACTSDMDCLNRALRVQCSSDCSVPYCSNRRFWKEDCGNKLCVSNGPRSKRVLKTKIARRAGEFLCEYAGEVITREQAQEKFAQDRDPRIIAIAAHLFVDATKRSNIARFIKHSCKPNSRLEVWSVNGFYRAGVFALSDLNPNAEITVDKSDLLPFDMACNCGATECKRVIRGVRWRCADPNEKIVTRRFVIRNRRKTIERSSHSGLPAILQTPMDENSSIRLKMKQVLAAFAFRVRKIDGSMSRTMLPHYTLIIKFLKTKGNNPNPVEFVSLFRKWLEAIDDDDLERAFVAIESHYMSSSILSSSLQSKKAKDNAPRARALSTSCPSPVPSKRGDADLSYLESLYPIGSYDPDDAWESYSTNKKGNAVRCICGALDEEGTMVQCDTCHFWLHVDCCQYVVRSNEKAQKSKNPPSDDGEYICDFCTNKQNGLRPSADVKLTEQPDVRFENCDYYRSLINRRGIQVVLNETVYVNRVLPEDHKAMLRNLREEKKGSKQKDTNKYRFPKAATSPLPIEKVDRKNARIFRVERLFVCPGNNRFVFGSFYAWPHETYADAGRVFSKKEVFATPYYETLPLDEVIGRCLVLDTATWCKGRPKVPKFKEDDVFLCEMQIGKTQRVFEKVPPKNRYPINTNSYVFTEFTHPKKVVRDFRPYDPSNPSPKPPKTSSIPSTSSIDPPQSSSDGLPEVDTKKLSKRHIQRVLKRLVKNGSRRS
What is the function of this protein?
Probable histone methyltransferase (By similarity).  Essential protein required to maintain expression of homeotic genes egl-5 and mab-5.  May play an analogous role to the trithorax Group (trxG) proteins.  TrxG proteins form multiprotein complexes that are required to maintain the transcriptionally active state of homeotic genes throughout development.  May act via a modification of chromatin.
What are the official names of this protein?
Probable histone-lysine N-methyltransferase lin-59, Abnormal cell lineage protein 59.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNJC1_MOUSE
Sequence: MWVPGFGSARLPQRRRSGLESSSVRPLWLLLLFLLAAVRPVRAWESGDLELFDLVEEVQLNFYEFLGVQQDASSADIRKAYRKLSLTLHPDKNKDENAETQFRQLVAIYEVLKDDERRQRYDDVLINGLPDWRQPVFYYRRVRKMSNAELALLLFIILTVGHYAVVWSIYLEKQLDELLGRKKRERKKKTGSKSVDAAKLGASEKNERLLIKPQWHDLLPCKLGIWFCLTLKALPHLIQDAGQFYAKYKETKLKEKEDALARIEIETLQKQKKVKVKKPKPEFPVYMPLENTYIQSYDHGTSIEEIEEQMDDWLENRKRTQKRQAPEWTEEDLSQLTRSMVKFPGGTPGRWDKIAHELGRSVTDVTTKAKELKDSVTSSPGMTRLSELKSNGQNSRPIKIATALPDDIITQREDSAGAMEDEEHEAAEGEQESATTEARPRRRKSARAAEAVTRVEPEEKLRGKRQKDFDISEQNDSSDEEKQRKERTRAAEEAWTQSQQKLLELALQQYPKGASDRWDKIAKCVPSKSKEDCIARYKLLVELVQKKKQAKS
What is the function of this protein?
May modulate protein synthesis.
What are the official names of this protein?
DnaJ homolog subfamily C member 1, DnaJ protein homolog MTJ1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Microsome membrane; Single-pass type I membrane protein.
Protein: MURG_CAUVN
Sequence: MSKLAVVAAGGTGGHMFPAQALAEALAARGWRVVLATDDRGALYADKFPAEERLALSAATAKSNDPLGMIKAGFVVLQGVMEARAAFKRLDPAVVVGFGGYPALPALLGALSQGRPTVIHEQNAVLGRVNRFLAPRVNEVACAFPILEKATPAVKACAHVVGNPVRPPVRALFDVPYLAPEVQLRVLVTGGSQGARLLSELIPEAVAKLPEEMRGRLKVFQQARAESMEQARKVYRNAMVECEVAPFFRDMAGYLRQSHLVIGRSGASTCTELAVAGRPSILIPLKIAADDHQRFNARLLEEAGGAAVCLEDELTVDVMAAALKALLSKPERLEKMAAGARSAAKPNAAEELADLVEKTAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GATC_PSEA7
Sequence: MALERSDVEKIAHLARLGLSEADLPRTTETLNNILGLIDQMQAVDTSGVEPLAHPLEATQRLRPDAVTETDHRDAYQTIAPAVEEGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CCG2_MOUSE
Sequence: MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGVKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVHNCIQKDSKDSLHANTANRRTTPV
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization.  Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.  Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity).
What are the official names of this protein?
Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Stargazin, Transmembrane AMPAR regulatory protein gamma-2, TARP gamma-2.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: CLPP1_RHOBA
Sequence: MSDPFGSPFPSLHDQNLNAQHAMASDHRLANAASYQSYQRQRQMTLGDLLLENRIVFMQGEIHYANANEIVMKLLYLQSENRRKDIHLYINSPGGSVTATLAIYDTMQMLSCPVATYCVGEACSGAAVLLIGGAKGKRFCLPNSRVMMHQPLGGVSGQVSDIEIQAAEMFRYRDKLNEIISSHCGKSVEQIAKDTDRDFFLDAQQAKEYGLVDDLLLGTPASEEDED
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_BACAA
Sequence: MAKKSMIAKQKRTPKFKVQEYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: FLEN_PSEAE
Sequence: MKQMGSMHPVQVIAVTGGKGGVGKTNVSVNLALALADLGRRVMLLDADLGLANVDVLLGLTPKRTLADVIEGRCELRDVLLLGPGGVRIVPAASGTQSMVHLSPMQHAGLIQAFSDISDNLDVLVVDTAAGIGDSVVSFVRAAQEVLLVVCDEPTSITDAYALIKLLNRDHGMTRFRVLANMAHSPQEGRNLFAKLTKVTDRFLDVALQYVGVIPYDESVRKAVQKQRAVYEAFPRSKASLAFKAVAQKVDSWPLPANPRGHLEFFVERLVQHPATGSAV
What is the function of this protein?
ATPase that plays an important role in maintaining flagellar number in Pseudomonas aeruginosa (PubMed:10629180, PubMed:28065505).  Exhibits anti-activator activity against FleQ, the global transcriptional regulator of flagellar genes (PubMed:22581773, PubMed:28065505).
What are the official names of this protein?
Antiactivator FleN.
What is the protein family that this protein belongs to?
Belongs to the ParA family.
Protein: KC1DB_DANRE
Sequence: MELRVGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGANRTAEEADRERRERDERMRHSRNPAARGIPAASGRPRPTQDGAPPTPLTPTSHTANTSSPRPVTGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQNSIPFDHHGK
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  Central component of the circadian clock.  May act as a negative regulator of circadian rhythmicity by phosphorylating per1 and per2, which may lead to their degradation.  Participates in wnt signaling (By similarity).
What are the official names of this protein?
Casein kinase I isoform delta-B, CKI-delta-B, CKId-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TEANC_MOUSE
Sequence: MSDKNQIIARASLIEQLVSKRYFEDIGKQLTELEMIYVSKEHLQETDVVRAVYRVLKNCPSVTLKKKAKCLLAKWRGFYKSTHCKPRQSPKVLHTNANKEESAAVSQDVSQDETSGSSHSEIMGLCSSLSRLLPQDAAKPAAAIGSESSTAQMEINEGYLKGDDSECTRKSSGVFQGTLVSVRSKCVELLYTALASSCTDHTEVHIWQNLAREIEEHIFTLHSNNIKKYKTSIRSKVANLKNPRNFHLQQNFLSGTMSAREFAEMSVLDMASQELKQLRASYTESSIQEHCLPQSVDGTWTNKIKCRRCDKYNCKVTVIARGTLFLPSWVQNSNPDEQMTYVICNECGEQWYHNNWVCL
What are the official names of this protein?
Transcription elongation factor A N-terminal and central domain-containing protein, TFIIS central domain-containing protein 1.