PharMolix/UniProtQA huggingface dataset:
Protein: ENCAP_MYXXD
Sequence: MPDFLGHAENPLREEEWARLNETVIQVARRSLVGRRILDIYGPLGAGVQTVPYDEFQGVSPGAVDIVGEQETAMVFTDARKFKTIPIIYKDFLLHWRDIEAARTHNMPLDVSAAAGAAALCAQQEDELIFYGDARLGYEGLMTANGRLTVPLGDWTSPGGGFQAIVEATRKLNEQGHFGPYAVVLSPRLYSQLHRIYEKTGVLEIETIRQLASDGVYQSNRLRGESGVVVSTGRENMDLAVSMDMVAAYLGASRMNHPFRVLEALLLRIKHPDAICTLEGAGATERR
What is the function of this protein?
Shell component of a type 1, iron-storage encapsulin nanocompartment.  Encapsulin nanocompartments are 32 nm in diameter with an iron- and phosphorus-rich core (4Fe:1P) about 24 nm in diameter.  Upon expression in E. coli most particles are 32 nm, 20% are 18 nm.  The core is filled with an average of 14 dense granules, 5-6 nm in diameter that are not evenly distributed.  Each nanocompartment is estimated to hold 30,000-35,000 Fe atoms (PubMed:25024436, PubMed:31194509).  The minor proteins EncB, EncC and EncD probably lie against the interior face of the nanocompartment (Probable).
What are the official names of this protein?
Type 1 encapsulin shell protein EncA.
What is the protein family that this protein belongs to?
Belongs to the encapsulin family. Family 1 subfamily.
What are the subcellular locations of this protein?
Encapsulin nanocompartment.
Protein: FIS_PASMU
Sequence: MLEQQRNPADALTVSVLNSQSQVTNKPLRDSVKQALRNYLSQLDGQDVNELYELVLAEVEHPMLDMVMQYTRGNQTRAATMLGINRGTLRKKLKKYGMG
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: ACTN4_BOVIN
Sequence: MVDYHAANQSYQYGPSSGSNGAGGGGTMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYERLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEKQLETIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANIVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSFSTALYGESDL
What is the function of this protein?
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures.  This is a bundling protein.  Probably involved in vesicular trafficking via its association with the CART complex.  The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.  Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2.  Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions.  May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA.
What are the official names of this protein?
Alpha-actinin-4, Non-muscle alpha-actinin 4.
What is the protein family that this protein belongs to?
Belongs to the alpha-actinin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell junction. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, perinuclear region. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity).
Protein: EFTS_ARTPT
Sequence: MAAVTAALVKELRERTGLGMMECKKALVEAEGDIERAIDDLRKSGQAKAAKKAGRTAAEGAIAVAVSGDGKTAIMVEINSETDFVARDDNFLGFANKVAEAALAAAKTEAADIAGVELADGSTVEQAREALIQKIGENIQVRRAAILSAESALGAYVHGGKIGVLVALKGGDEALGRDVAMHVAAVAPQVVNPSEVPESDLEREKEIIRAQPDMAGKPAEIVEKMLGGRIQKFLKEISLVEQPFVKD
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_BURTA
Sequence: MKSLFRPLIVVFVVLAAVTGLAYPAVMTVFGQAVFPSQANGSLIEKDGKVVGSALIGQQFDAPQYFWGRLSATSPMPYNAAGSGGSNLGPLNPSLKDQVKGRLDALKAAGTDLSQPVPVDLVTASASGLDPEISPAAADYQVARVARARKMPEADVRRLVADNTAGRQFGVLGEPRVNVLKLNLALDAAQTAQ
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y3248_NOCSJ
Sequence: MTSSAAAAIKQALGAYGETLAARHLVGQGMVLLERNWRCEAGEIDLVLRDGDVLVVCEVKTRSSLRYGTPHEAVTDIKVARLRRLASRWVQDRGVAVRDIRIDLVGIVRPRRGSSVVDHVRGIG
What are the official names of this protein?
UPF0102 protein Noca_3248.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: ENO_CHLL3
Sequence: MPVIHKIHARQILDSRGNPTVEVDVYTESSFGRAAVPSGASTGVHEAVELRDGDKGVYLGKGVLKAVENVNTVIDEALRGMLVTEQEEIDARLLELDGTPNKSKLGANALLGVSMACAKAGAEYSGLSLFRYIGGTMANTLPVPMMNVLNGGAHADNTVDFQEFMIMPIGFSTYSDALRCGAEIFHALKALLHSRGLSTAVGDEGGFAPNLRSNEEAIELVVEAIGKAGYKAGSPASKGGLGDAQVMIALDPASSEFYDTEKKKYVFKKSDKRELSSEEMASYWEGWANTYPIISIEDGMAEDDWAGWKLLTEKIGDRVQLVGDDLFVTNSLRLAEGIEKGVGNSILIKVNQIGTLTETLRAIDLAKRNGYTSVISHRSGETEDSTIAQIAVATNAGQIKTGSMSRSDRMSKYNELLRIEEELGEQAIYPGKQAFRV
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: YTFE_SHIF8
Sequence: MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARKELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVERVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEHDEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALAGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_YERPE
Sequence: MIERIWSGQSRLYLLLLPLSWLYGAVTWLIRASYRLGLRSAWRSPVPVIIVGNLTAGGNGKTPVVIWLVEQLQQRGYRVGVVSRGYGGKSAVYPLLLSDNTTTAQAGDEPVLIFQRTGAPVAVSPKRADAIKALLQSHAVDFIITDDGLQHYALQRDFELVVIDGVRRFGNGWWLPAGPMREREGRLRSVDAAITNGGLAAEGEIPMQLVAREAVNLVTGQRQPAEQLQHVVAMAGIGHPPRFFATLNLLGIKPENEHAFADHQDYSLAQLSRLTSGPQILLMTEKDAVKCRAFALPNWWYLPVDAQLPSDRADKLLLNIQALSPDTK
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: FOLD_LISIN
Sequence: MGEIIDGKKLAKEIQEKVTSEVAELVKQGKKPGLAVVLVGDNQASRTYVRNKQKRTEEAGMKSVLIELPETVTEEKLLKVVEELNEDNTIHGILVQLPLPKHISEEKVIDAISFDKDVDGFHPVNVGNLFIGKDSFVPCTPAGIIELIKSTGTQIEGKRAVVIGRSNIVGKPVAQLLLNENATVTIAHSRTKDLPQVAKEADILVVATGLAKFVKKEYIKPGAIVIDVGMDRDENNKLCGDVDFDDVKEQAGFITPVPGGVGPMTITMLLANTLKAAKRIWKMN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DNAK_BACAA
Sequence: MSKIIGIDLGTTNSCVAVMEGGEPKVIPNPEGNRTTPSVVAFKNEERQVGEVAKRQAITNPNTIMSVKRHMGTDYKVEVEGKDYTPQEISAIILQNLKASAEAYLGETVTKAVITVPAYFNDAERQATKDAGRIAGLEVERIINEPTAAALAYGLEKQDEEQKILVYDLGGGTFDVSILELADGTFEVISTAGDNRLGGDDFDQVIIDHLVAEFKKENNIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFISAGAAGPLHLELTLTRAKFEELSAGLVERTLEPTRRALKDAGFAPSELDKVILVGGSTRIPAVQEAIKRETGKEPYKGVNPDEVVALGAAVQGGVLTGDVEGVLLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMSADNKTLGRFQLTDLPPAPRGIPQIEVTFDIDANGIVNVRAKDLGTSKEQAITIQSSSGLSDEEVERMVQEAEANADADQKRKEEVELRNEADQLVFQTDKVVKDLEGKVDAAEVAKATEAKEALQAAIEKNELEEIRAKKDALQEIVQQLTVKLYEQAQAAAGQAEGAEGAQDAGAKKDNVVDAEFEEVKEDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LFG4_MOUSE
Sequence: MADTDPGYPRSSIEDDFNYGSCVASASVHIRMAFLRKVYSILSLQVLLTTVTSALFLYFQALRTFVHESPALIVVFALGSLGLIFALTLHRHTHPLNLYLLFAFTLSESLAVAAVVTFYDVYLVLQAFIMTTAVFLGLTAYTLQSKRDFTKFGAGLFAGLWILCLAGFLKLFFYSETMELVLASLGALLFCGFIIYDTHSLMHRLSPEEYVIAAISLYMDIINLFLHLLKFLEAVNKK
What is the function of this protein?
Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli.  Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release (By similarity).
What are the official names of this protein?
Protein lifeguard 4, Transmembrane BAX inhibitor motif-containing protein 4, Z-protein.
What is the protein family that this protein belongs to?
Belongs to the BI1 family. LFG subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: UBIQP_CRIGR
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKQGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSNTIKKSKQEDGRTFLTTLSRKSTPCACSWA
What is the function of this protein?
Ubiquitin Exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BCLF1_HUMAN
Sequence: MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE
What is the function of this protein?
Death-promoting transcriptional repressor.  May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
What are the official names of this protein?
Bcl-2-associated transcription factor 1, Btf, BCLAF1 and THRAP3 family member 1.
What is the protein family that this protein belongs to?
Belongs to the BCLAF1/THRAP3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Nucleus, nucleoplasm.
Protein: MDHM_CAEEL
Sequence: MSLPAKTLVQAAANSGLRAVSVRHSSQAPKVALLGAAGGIGQPLGLLLKQDPLVAHLALYDVVNTPGVAADLSHIDSNAKVTAHTGPKELYAAVENADVIVIPAGVPRKPGMTRDDLFNTNAGIVRDLAAVIAKASPKALIAIITNPVNSTVPIASEVLKKAGVYDPKRVFGVTTLDVVRSQAFVSELKGHDASKTVVPVVGGHAGITIIPLLSQVKPSTKFSEEEISKLTPRIQDAGTEVVNAKAGAGSATLSMALAGARFANALVRGIKGEKNVQCAYVASDAVKGVEYFSTPVELGPNGVEKILGVGKVSAYEQKLIDASVPELNKNIAKGVAFVKGN
What is the function of this protein?
Catalyzes the reversible conversion of (S)-malate to oxaloacetate in the citric acid cycle.
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ACCA_RHOCS
Sequence: MHFLEFEKPIADLEGKIEELRTLTDGGDINIADEVKKLQEKVDKLLRSTYAKLTPAQKVQVARHPERPHCLDYIQRLITDFTPLAGDRLFAEDRAIVGGLGRFRGRSVVVIGQERGHDTESRVRHNFGMAKPEGYRKAQRLLQLADRFRLPVVTLVDTAGAFPGVSAEERGQAEAIARSIETCLRLKVPLVSAVIGEGGSGGAIAIATADRVLMLEHAIYSVISPEGCASILWRSAANASDAAQALRLTAQDLKELGVIDRVVMEPVGGAHRRREEMIATLGNAIEDALDDLREQDGATLRLNRRQKFLDIGQKGLG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_NITOC
Sequence: MEVYLVGGAVRDKLLGRPVKERDYVVVGTTPANLLAQGYRPVGKDFPVFLHPQTQEEYALARTERKTGPGYKGFEVDAAPDVTLEEDLQRRDLTINAIAEAADGSLLDPFGGQQDLARGILRHVSPAFAEDPVRILRAARFAARFNFKVAPETLALMEAMVTAGEADHLVPERVWRELERALGESYPRRFFEILRACGALARIFPEIECLFGVPQPRRYHPEIDTGIHTLKVLEIAAHLSSDTQVRFAALTHDLGKGQTPSHEWPHHYGHGERGVALVLTLCQRLRVPKAYQALAVQVARYHNLVHQAQELRPGTILKLLNRVDAFRRPSRFEQFLLACEADARGRSGLENRPYPQANQLRLAFRAAAAVTARPLVAAGLRGEAIAEQLQQQRIKAIKQAVHTERG
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: SYL_RHOP2
Sequence: MSNERYNARESEPKWQAKWDEAKIFATRNDDPRPKYYVLEMFPYPSGRIHMGHVRNYTMGDVVARTMRARGHNVLHPMGWDAFGLPAENAAIERKVAPKAWTYDNIASMKKQLQTMGLSLDWAREFATCDPTYYKHQQKMFLDFLKVGLAERETRKLNWDPVDMTVLANEQVIDGRGWRSGAVVEQREMNQWVFKITRYAQDLLDALETLDRWPDKVRLMQRNWIGRSEGLLVRFALDAATTPAGETELKIFTTRPDTLFGAKFMAIAPDHPLAQAAAAKNEKIAAFVEECKKRGTAQAEIDTAEKQGIDTGIRALHPFDPTWQIPVYVANFVLMEYGTGAIFGCPAHDQRDLDFVNKYQLGNTPVVCPEGQDPLSFVITDEAYDGDGRLINSRFLDGMSIADAKEEVAKRLETATLGNAPVGERKVNFRLRDWGISRQRYWGCPIPVIHCEVCGVVPVPDKDLPVVLPEDVSFDKPGNALDHHPTWKHVPCPQCGGKAQRETDTMDTFVDSSWYFARFTDPWNETAPTTPDVVNRMLPVDQYIGGVEHAILHLLYSRFFTRAMKATGHLGLDEPFRGMFTQGMVVHETYRTADGHFASPAEVAIVAEGDGRRATLLDGGTPVEIGPIEKMSKSKRNTVDPDDIIGSYGADTARWFMLSDSPPDRDVIWSEEGVKGASRFVQRLWRMVNDAAAIARSAPAERPATFGPEALAVRKAAHGALDKVLSGIERLAFNVSLAHIREFANSFGEALAKPGQPSPDLAWAIREAAVILVQLFHPMMPHLAEECWAALGRPGLVSEALWPQIERDLLVEDSITLPVQVNGKKRGDITVARDANTQEIEAAVLALDAVRQALDGKPVRKVIVVPQRIVNVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBE2S_DROSE
Sequence: MSSQYSNVENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLNKDFPLTPPKAYFLTKIFHPNVAANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKMLLERYDDYSQRARMMTEIHAQPAKCGVGATGDAKDDGGPSTKKHAGLDKKLQDKKKEKLLKEKKRMLKRL
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by specifically elongating polyubiquitin chains initiated by the E2 enzyme vih/UbcH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 S, E2 ubiquitin-conjugating enzyme S, Ubiquitin carrier protein S, Ubiquitin-protein ligase S.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: FADB_SHELP
Sequence: MIYQSPTIQVELLEDNIARLCFNAEGSVNKFDRETLNSLNDALDALAQTQGVKGLMLTSGKDAFIVGADITEFLGLFAQDDNVLQGWLEDANKVFNKLEDLPFPTISAIKGFALGGGCETILATDLRIADTSARIGLPETKLGIIPGFGGTVRLPRVIGADNALEWITTGKDQRPEAALKVGAIDAVVAPELLETAACQMLQDAISEKIDWQARRQRKLSPLTLPKLEAMMSFATAKGMVFKVAGKHYPAPMAVVEVIEKAALSERAEALQVEHQAFIKLAKTDVAKALIGIFLNDQLVKGKAKKAAKQAQAVNSAAVLGAGIMGGGIAYQSASKGTPIVMKDINQAALDLGLNEAAKLLTAQINRGRSTPAKMAGVLNNITATLDYNALKQADVVVEAVVEHPKVKATVLAEVEQVVGEDAIITSNTSTISINLLAKSLQKPERFCGMHFFNPVHKMPLVEVIRGEHSSEETVASVVAYAAKMGKTPIVVNDCPGFFVNRVLFPYFAGFSGLLEDGADFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMAEGFPDRMAKEGKDAIDVMFEADRFGQKNGKGFYQYSVDRRGKPKKEVDPLSYELLGNAFGEQKEFSSDEIIARTMIPMIIETVRCLEEGIIATPAEADMGLVYGLGFPPFRGGVFRYLDTLGVANFVALADQYAHLGGLYQVTDKMRELAATNGSYYPA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: CTG1_CAEEL
Sequence: MLVSPTAAATSIEQQTIRDLRSIVPQIDNLNDGYVLRWLRAKEGRFDETAESLKKHVTFRNAWHLDKIEQWTPPECLEKYCGYGLLGDTEGRPILMSLLGNVDVEGLLRSVASLDYIKFSLAAIEKGMKLCEEKAKESGRPFEQMTLVFDLENITSAHFSCKQFASSFTTLVSLFQDHYPLFLRKILIIRAPEMARIAYASITAILQDPITRLVEMPSESDWKWSLAQIVNLDAWPMYWGGNLVENGDPKCPSRIKYGGGAVDESYFVDPKKAMADYDQLTTVYAGDKHLIQIKVKRPSRISWTYMTDEDDIGFEIHYDKTGSCDKLTEMETVYPYIRLECTNVPITGHLDVTDVGNYVLEFDNYYSWFSAKQLRYNIEIEDL
What is the function of this protein?
Vesicle trafficking protein (Probable).  Functions in uterine cells to promote basement membrane (BM) mobility and BM gap formation during tissue remodeling (PubMed:27661254).
What are the official names of this protein?
Protein ctg-1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PSR2_PHYIT
Sequence: MGCRYAVLALAVAYFAGSIAANDSQIVAVKGPASIRFTPAIHVVRGRFLRAANTADERNEDRGINLKSMPGFEKIASLFTKKNTPGPLLSWFEKKKSPDYVFLKLKINKGKQQLFDHPDWNVWVQYTTSVVKSDPEEAMIAALRTHYTDDILSKLLESAKNVPKTSGLATKMQMEHWVASKTPSQMFQFLRLDKVRNGVLDDPTLSIWINYMKLYNSKPVNKKQQVTLVSMLTTHYKDRGVLDIIEAAKKVPKTAPAARQLEMEQIQFWLKNGKSPDELLTVLSLDKAGNQLLASPRFKFWSKYVDNYNRDFPDEATTVMATLRNQLGDEDITPILIAAGKVPSTEKAAAKLQAEQFKSWLRENEDPAKVFQLLKLDNSADDLLGSPQFKLWGKYVEDLNLKPEHNDLQVSIITILRKNYGDDVLGNMVLAGKKAPSTSFMARRLEDELYKGWIAAGSSPDGVFKHLKFDKAGENVIQSPLWGLYTKFLEHYYKSFPTPMMSALAKGYDGDALAKLLIAAEKIPTSNTLATKLQTGQIQRWLDDKDQPGKIFKALLLDDMADDILTSPLFNTWTRYLDEFNKKFPDEKVSMTDTFRTSLDDETLKSLLITAKELPDMKTLSTKLQTVQIERWLASKTSPEDAFAVLALNKAGGNVLSKPLLNTWAAYLESFNAKFPRSRVSMIDTFREFFGDKALLTTLAAAKEVESTKKVATSLQDSLLSKWVLAKKPPSGVAKLVGTDEAGAKLLKTYTTKYMERYGQ
What is the function of this protein?
Secreted effector that possesses RNA silencing suppression activity by inhibiting the biogenesis of small RNAs in the host plant to promote enhanced susceptibility of host to the pathogen during infection (PubMed:25387135, PubMed:27503598).  Interferes with secondary siRNA production by associating with host dsRNA-binding protein DRB4 (By similarity).  Inhibits the host salicylic acid pathway during infection (By similarity).
What are the official names of this protein?
RxLR effector protein PSR2, Suppressor of RNA silencing protein 2.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: SL2_ECHOC
Sequence: MGRFIFVSFGLLVVFLSLSGTEAGVCCPLGWSGYDQNCYKAFEELMNWADAEKFCTQQHKGSHLVSLHNIAEADFVVKKIVSVLKDGVIWMGLNDVWNECNWGWTDGAQLDYKAWNVESNCFIFKTAENHWSRTDCSGTHSFVCKSPA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 2, C-type lectin 2, CTL-2.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.