PharMolix/UniProtQA huggingface dataset:
Protein: DFB4A_HUMAN
Sequence: MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
What is the function of this protein?
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria (PubMed:9202117, PubMed:10837369).  Antimicrobial activity against P. aruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM (PubMed:10837369).  Also exhibits antimicrobial activity against the yeast C. albicans (PubMed:9202117, PubMed:10837369, PubMed:30050988).  Permeabilizes C. albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death (PubMed:30050988).  Acts as a ligand for C-C chemokine receptor CCR6 (PubMed:10521347, PubMed:20068036).  Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells, such as immature dendritic cells and memory T cells (PubMed:10521347, PubMed:20068036).
What are the official names of this protein?
Defensin beta 4A, Beta-defensin 2, BD-2, hBD-2, Defensin, beta 2, Skin-antimicrobial peptide 1, SAP1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family. LAP/TAP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ESSB_STAAN
Sequence: MVKNHNPKNEMQDMLTPLDAEEAAKTKLRLDMREIPKSSIKPEHFHLMYLLEQHSPYFIDAELTELRDSFQIHYDINDNHTPFDNIKSFTKNEKLRYLLNIKNLEEVNRTRYTFVLAPDELFFTRDGLPIAKTRGLQNVVDPLPVSEAEFLTRYKALVICAFNEKQSFDALVEGNLELHKGTPFETKVIEAATLDLLTAFLDEQYQKQEQDYSQNYAYVRKVGHTVFKWVAIGMTTLSVLLIAFLAFLYFSVMKHNERIEKGYQAFVKDDYTQVLNTYDDLDGKKLDKEALYIYAKSYIQTNKQGLEKDKKENLLNNVTPNSNKDYLLYWMELGQGHLDEAINIATYLDDNDITKLALINKLNEIKNNGDLSNDKRSEETKKYNDKLQDILDKEKQVKDEKAKSEEEKAKAKDEKLKQQEENEKKQKEQAQKDKEKRQEAERKK
What is the function of this protein?
Component of the type VII secretion system (Ess).  Required for the secretion of EsxA and EsxB.
What are the official names of this protein?
Type VII secretion system protein EssB.
What is the protein family that this protein belongs to?
Belongs to the EssB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PGK_METS5
Sequence: MNIPTLDDLNFSNSKVLVRIDINSPVDSKTGKLLDDSRIKAHVETIRELVSRGNGVVLVSHQGRPGDNDFTDLEEHSRLLQKHLDMEVEFVGDVMGPYARERIRNMKLGSVLLLDNVRFVSEELIEASPLQHSRSFLVRRLQPLFQGYVNDAFATAHRSQASLVGFPLVLRSSAGRVMEKEVSALAKVFNEGEEPKVFIMGGGKVLDSLRIIENLVKRRLADRILTGGLIAELFAVAKGLDLGKDNLQVLEKAGVLSLVPRARKLLLSGAPVEIPVDFKVEKGGQVYEEPANKVTAVIKDVGSTTVGIYSSFIRDAKIIVMRGPMGVIEDERFRESSRTLLKNSLESPGYLIVGGGHMISLLGGIGPLDSSKVHVSTGGGALLLFLAGERLPALEALDISAREVLKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPR1_ORYSI
Sequence: MEPPTSHVTNAFSDSDSASVEEGDADADADVEALRRLSDNLAAAFRSPEDFAFLADARIAVPGGGGGGGDLRVHRCVLSARSPFLRGVFARRAAAAAGGGGEDGSERLELRELLGGGGEEVEVGYEALRLVLDYLYSGRVGDLPKAACLCVDEDCAHVGCHPAVAFMAQVLFAASTFQVAELTNLFQRRLLDVLDKVEVDNLLLILSVANLCNKSCMKLLERCLDMVVRSNLDMITLEKSLPPDVIKQIIDARLSLGLISPENKGFPNKHVRRIHRALDSDDVELVRMLLTEGQTNLDDAFALHYAVEHCDSKITTELLDLALADVNHRNPRGYTVLHIAARRREPKIIVSLLTKGARPADVTFDGRKAVQISKRLTKQGDYFGVTEEGKPSPKDRLCIEILEQAERRDPQLGEASVSLAMAGESLRGRLLYLENRVALARIMFPMEARVAMDIAQVDGTLEFNLGSGANPPPERQRTTVDLNESPFIMKEEHLARMTALSKTVELGKRFFPRCSNVLDKIMDDETDPVSLGRDTSAEKRKRFHDLQDVLQKAFHEDKEENDRSGLSSSSSSTSIGAIRPRR
What is the function of this protein?
Key positive factor of disease resistance (PubMed:15986920, Ref. 2).  Involved in defense response against the bacterial blight disease caused by Xanthomonas oryzae pv.  oryzae (Xoo).  Plants over-expressing NPR1/NH1 acquire high levels of resistance to Xoo, express constitutively defense genes and develop lesion-mimic spots on leaves at pre-flowering stage (PubMed:15986920).  Involved in basal resistance to the blast pathogen Magnaporthe oryzae.  Plants over-expressing NPR1/NH1 have increased resistance to M. oryzae infection (Ref. 2).  Plays an essential role in benzothiadiazole (BTH)-induced resistance to the blast fungus disease caused by Magnaporthe oryzae (By similarity).  Functions as a transcriptional coactivator of TGA2. 1 and LG2 in vitro (By similarity).  Involved in defense response against herbivore.  Plants silencing NPR1/NH1 have increased herbivore-induced trypsin proteinase inhibitors and volatiles, which reduces the performance of the striped stem borer (SSB) Chilo suppressalis (By similarity).
What are the official names of this protein?
BTB/POZ domain and ankyrin repeat-containing protein NPR1, OsNPR1, NPR1 homolog 1, OsNH1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Accumulation in nucleus when present as monomer.
Protein: MIAA_SYNWW
Sequence: MYKLAAIVGPTAVGKTNISLEVARQINGEIISCDSMQLYRGMNIGTAKASKEEQNIVAHHLIDIADPHENFTVARYQSLVKDLISTINARGKIPILVGGTGLYYQSVVDDYTFFPMEVRQSIRDKWNAIIQEKGLPHVYRLLEQIDPAYAQIISPNDQKRVVRALEVYELTGKAFSTLQDRAENTYYLAVVGLYLERRELYARIERRVDEMIKKGLIEEVAALREKGIDLSYNSMQALGYKQVFYFLEGFINREELLNEIKRETRRYAKRQLTWFKKDQRIKWFNVGDFSDEELLVKNICTFMEGQFGIV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HGGL_SECCE
Sequence: MALLVGGTLNPTTHLSLRSRAGRNSENVWLRSAASSQTSKGRFCNLTVRAGTPSKPSEPIGPVFTKLKPWQIPKRDWFSKDFLFGASTSAYQIEGAWNEDGKGPSTWDHFCHTYPERISDGTNGDVAANSYHMYEEDVKALKDMGMKVYRFSISWSRILPNGTGKPNQKGIDYYNNLINSLIRHGIVPYVTIWHWDTPQALEDKYGGFLDKQIVNDYKYFAELCFQSFGDRVKNWFTFNEPHTYCCFSYGEGIHAPGRCSPGLDCAVPEGDSLREPYTAGHHILLAHAEAVELFKAHYNKHGDSKIGMAFDVMGYEPYQDSFLDDQARERSIDYNMGWFLEPVVRGDYPFSMRSLIGDRLPMFTKEEQEKLGSLCDIMGLNYYTSRFSKHVDISSDYTPTLNTDDAYASSETTGSDGNEIGPITGTYWIYMYPKGLTDLLLIMKEKYGNPPIFITENGIADVEGDPEMPDPLDDWKRLDYLQRHISAVKDAIDQGADVRGHFTWGLIDNFEWGSGYSSRFGLVYIDKEDGNKRKLKKSAKWFAKFNSVPKTLLKTTNNNATVTASVSV
What is the function of this protein?
Involved in defense of young plant parts against pests via the production of benzoxazolinones (hydroxamic acids) from hydroxamic acid glucosides.  The preferred substrate is DIBOA-beta-D-glucoside.  Can also use esculin and genistein glucoside as substrates, but no activity with salicin, p-nitrophenyl-alpha-glucoside or substrates related to cell wall components.
What are the official names of this protein?
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic, Beta-glucosidase, ScGlu.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MYF6_PIG
Sequence: MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPPEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAINYIERLQDLLHRLDQQDKMQELGVDPFSYRPKQENLEGADFLRTCSSQWPSVSDHSRGLVMTAKEGGTNIDSSASSSLRCLSSIVDSISSEEHTLPCVEEVGEK
What is the function of this protein?
Involved in muscle differentiation (myogenic factor).  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein (By similarity).
What are the official names of this protein?
Myogenic factor 6, Myf-6.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL29_LEPIC
Sequence: MKKIKLQELKDSEILEQLEEARKVLRNSRFQYGVARSLENPKIISNTKKKIAKLLTIQRERQLKANPGERKSRVFSRAKRKKKNLARLSAKAKG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RCF1_BOTFB
Sequence: MSNSTPLPSSFDGDTDFYEENRWQKLTRRLKEEPLIPLGCILTSLALVGASRSIRAGDHNRTQRMFRARIYAQGFTLLAMVAGSMYWDSDRKKRKEFEGVLAETKAKEKNEAWIRELEARDEEEKEMRRARDERRRRAEGRPAPKAVVTDAPAEEGEKPKGGVMEQMSGLVWGKK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: QCR6_DICDI
Sequence: MQTSECKVKGPIQEGCASGCEKSWSAYQACSGRVAKLEHDEKANCLGQFLEHVQCIDKCVGPKLFAQLK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Probable cytochrome b-c1 complex subunit 6, Ubiquinol-cytochrome c reductase complex subunit 6.
What is the protein family that this protein belongs to?
Belongs to the UQCRH/QCR6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: HYUA_PSESN
Sequence: MKLFGVDVGGTFTDIIFSDTETRVTAIHKVPTTLDDPSTGVVQGILELCDRQYIDRTAIDHVFHGTTIATNAILEYDGAKTGMITTEGYRDIIHIGRHQRPQNYSIMQEIPWQDRPLVQRRHRLAIAERMGPVKGQVITPVQEDQVRGAVATLKERGVDSIIVNFLFSYTNPEHEQRVKEIIEEEYPEAFVTISSEVSPQFREFERFTTASINGFVGPKVKNYIQNLEQSLKDSGISAELHIMCSNGGVATPKTVSEKPVNTLLSGPAAGILGGAWAGELTNRQKLITFDVGGTSADIGIITDSGYGESSARDTWIAGYPVMVPMIDIHTIGAGGGSIAHIDEGGAFKVGPRSAGSRPGPACYGHGGLKPTVSDANVVLGRIDEHNFLGGEMKIYTNAAYKVIDELAGQLDLSRERTAEGVLQIMNNNMANAIREKTIQKGEDPREFSLVAFGGAGPLHAVEVAQILNIPEVIIPLYPGINSATGLLTTDLKYDVIKTEFMMSTNMDFSGLNEDLAGLETQLINQLKEDGVSKQDIRILRSADCRYAGQGYELRVDLPDVFLDEETIVDALNNFHESHKAEYGHNFTDSPIEFVNIRVTGTGYMPKIEKQAIHHEYQLEDALLKTGDATFNIDGSLVKVEINFYQREKIPVGAEFNGPCIVLQKDTTTVIPPNCTAYIEEYGNMIIKVGV
What is the function of this protein?
Involved in the asymmetric conversion of racemic 5-substituted hydantoins to the corresponding L-amino acids.  HyuA and HyuB are both required for the conversion of D- and L-5-substituted hydantoins to corresponding N-carbamoyl-D- and N-carbamoyl-L-amino acids, respectively.
What are the official names of this protein?
Putative D-/L-hydantoinase subunit A, Hydantoin utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the HyuA family.
Protein: ATAT_RAT
Sequence: MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIVDELGKASAKAQHLPAPITSALRMQSNRHVIYVLKDTSARPAGKGAIIGFLKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSPKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRSPTPSLRATRHSRAAVVDPIPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPDRGPLRPFVPEQELLRSLRLCPPHPTARLLLATDPGGSPAQRRRTRETPWGLVAQSCHYSRHGGFNTSFLGTGNQERKQGEQEAEDRSASEDQVLLQDGSGEEPTHTVAPRAQAPPAQSWMVGGDILNARVIRNLQERRNTRPW
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.  Required for normal sperm flagellar function.  Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells.  May facilitate primary cilium assembly.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase 1, Alpha-TAT, Alpha-TAT1, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane, clathrin-coated pit. Cell junction, focal adhesion. Cell projection, axon. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Protein: PIMA_MYCS2
Sequence: MRIGMVCPYSFDVPGGVQSHVLQLAEVLRDAGHEVSVLAPASPHVKLPDYVVSGGKAVPIPYNGSVARLRFGPATHRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTSTTKSLTLSVFQGILRPYHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFADAPLLDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEILIVGRGDEDELREQAGDLAGHLRFLGQVDDATKASAMRSADVYCAPHLGGESFGIVLVEAMAAGTAVVASDLDAFRRVLADGDAGRLVPVDDADGMAAALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVYETVSGAGIKVQVSGAANRDETAGESV
What is the function of this protein?
Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM).  Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) (PubMed:12068013, PubMed:19638342, PubMed:19520856).  In contrary to PimB, the mannosyltransferase PimA is unable to transfer a mannose residue to the position 6 of the phosphatidyl-myo-inositol of PIM1 (PubMed:19638342).
What are the official names of this protein?
Phosphatidyl-myo-inositol mannosyltransferase, Alpha-mannosyltransferase, GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase, Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase, Phosphatidylinositol alpha-mannosyltransferase, PI alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GUAA_STAAC
Sequence: MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PUR7_CHLP8
Sequence: MNKLTLLHEGKAKKVWQTDDPDLIIQEFKDDATAFNNKKKGSIADKGVTNNAIASRLFTMLGENGIPTHFVSKLNDRDMLCKKLDILLIEVVTRNVAAGSLVRRYGFAEGTVLEKPIVELYLKNDDLDDPLMNEDHAVALGLGTYEEVAQLKDMAEKINSLLVPWFAERKLRLVDFKLEFGRHKGEILLGDEISPDTCRFWDAESGEKLDKDRFRLDLGGVEDAYSEVKRRVLEQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RS20_BURCM
Sequence: MANSAQARKRARQAAKANSHNSALRSKFRTAIKSVRKAVEAGDQAKAAELFKAAVKTIDTIADKKIVHKNKAARSKSRLAAAVKGLQAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: EF2_SULIY
Sequence: MPRYKTVEQVLSLMKDRTRVRNIGIIAHVDHGKTTTSDTLLAASGIISPKVAGEALALDYLSVEQQRGITVKAANISLYHEAEGKGYVINLIDTPGHVDFSGRVTRSLRVLDGSIVVVDAVEGIMTQTETVLRQSLEERVRPILFINKVDRLVKELKLSPQEMLNRLLDIIRQVNNLIDMYGEPEFKEKWMINPQAGNVIFGSAKDKWGFSLPMAQKKGINMKNVIDAYTASDKSKLEELAAQAPINEALLDAAIKFVPNPIEAQKYRIPKIWKGDLDNELAKAMLNADPNGPIVFMITDMKVDPHAGLVATGRVFSGTLRSGEELWLVNAKTSQRILQVSLYMGPTRELAEEIPAGNIAAVLGLDRARSGETAISVGFSNVQGSFERLHYISEPVVTIAVEPKNPKDLTKMIDALRKLSIEDPNLVVKINEETGEYLLSGMGFLHLEVSLQLLRENYGIDVVTTPPIVVYRESIRAKSQVFEGKSPNKHNKFYLSVEPLNDKTIELISNGTIREDMDSKEMAKILRDEASWDYDEAKRIIAIDENVNVFVDLTSGVQHLREVMDTVLQGFRLAMKEGPLAHEPIRGVKVILHDAVIHEDPAHRGPAQIYPAVRNSIFAGFLTSRPTLLEPIQKLDIRVPADLIGNVTAVITRKRGKILDVSQIANMSRITAEIPVSESYDMASELRGSTGGRAFWGTEFSRWAPVPDSILLDVVTKIRERKGLPKELPKVEDFLS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN_SALTY
Sequence: MMTMLRGWITMLVMLTAINAQAACSWPAWEQFKKDYISQQGRVIDPGDARKITTSEGQSYAMFFALAANDRPAFAQLFNWTQNNLAQGSLREYLPAWLWGQKDPDTWSVLDSNSASDGDIWMAWSLLEAGRLWKETRYTEVGTALLKRIAREEVLNVPGLGSMLLPGKIGFAEANSWRFNPSYLPPQLAQYFSRFGAPWSTLRETNLRLLLETAPKGFSPDWVRYESKQGWQLKAEKTLISSYDAIRVYLWAGMMHDGDPQKARLLARFKPMATLTMKNGVPPEKVDVVSGNAQGTGPVGFSAALLPFLQNRDAQAVQRQRVADHFPGSDAYYNYVLTLFGQGWDQHRFRFTVKGELLPDWGQECVSSR
What is the function of this protein?
Hydrolyzes carboxymethylcellulose.
What are the official names of this protein?
Endoglucanase, Carboxymethylcellulase, CMCase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 8 (cellulase D) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_RHOP2
Sequence: MALPEFTMRQLLEAGVHFGHQSHRWNPKMAEYIFGARNNIHIIDLAQTVPLMHRALQAISDTVAKGGRVLFVGTKRQAQDAVADAAKRSAQYFVNSRWLGGTLTNWKTISGSIKRLRHLDDVLNSGDASAYTKKERLTLQRERDKLDRSLGGIKDMGGLPDLIFVIDTNKEDIAIQEAQRLGIPVAAIVDTNCDPKGITYLVPGNDDAGRAISLYCDLIARAVIDGISRAQGESGIDIGASSRPPREDLPAAQATGFQGLSGPRGTPDDLKKLAGVSGDIEKKFNDLGIFHYWQLAELNADTAHQIGEEVGLPGRVDGWVAQAKGLTAEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CALR_HUMAN
Sequence: MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
What is the function of this protein?
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle.  This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed:7876246).  Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (PubMed:11149926).  Involved in maternal gene expression regulation.  May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).  Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).
What are the official names of this protein?
Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, grp60.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen. Cytoplasmic vesicle, secretory vesicle, Cortical granule. Cytolytic granule. Note=Also found in cell surface (T cells), cytosol and extracellular matrix (PubMed:10358038). During oocyte maturation and after parthenogenetic activation accumulates in cortical granules. In pronuclear and early cleaved embryos localizes weakly to cytoplasm around nucleus and more strongly in the region near the cortex (By similarity). In cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation (By similarity).
Protein: MIAB_RHOP2
Sequence: MAPPRKLHIKSYGCQMNVYDAQRMVDVLAPEGFVETASVDDADLVILNTCHIREKASEKVFSELGRLRLARDEASRDGRRMQIVVAGCVAQAEGDEIVRRQPAVDVVVGPQSYHHLPRLLAQAAQTGRALETEFPIADKFGFLPQPQPEAIRARGISAFVTVQEGCDKFCTFCVVPYTRGAEVSRPVAAILADVERLADHGVRELTLIGQNVNAYHGDGPDGRPWTLGRLLQRLAAVPGIVRLRYSTSHPNDVDDDLIAAHRDLDALMPFVHLPVQSGSDRILAAMNRKHTAADYRRVIDRFRAVRPEIAFSSDFIVGFPGETDADFEATLALVTQIGYAGAYSFKYSPRPGTPAAEMPEMVPAAVMDERLERLQQVIDAQQSAFNRAAIGRTVDVLFERAGRKPGQIVGRTAYLQPAHVFPPAGMAPDSLVGQILPVRVDSLERYSLLGELAATPPRHARPLAATGA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF232_IIV6
Sequence: MNNNQCMRKKLDELRNIARSYNISITGKKKQQLCDEIIDYQKNNPPRRSPSPRRSPSPRRISPECEQWLANKGINPRTGKAIKIGGPTYKKLEMECKEASPKIPSPVRQPSPVHSPVRSPVRQPSPVRFVEKTKGALNKMKKDQLIDFAQSLGLNPGKLLKPALVDLIFVNQKPPRRSPSPRRSPSPRRSPSPRRSPSPRPVFVEKTKGALNKMKKDQLIDLAQSLGLNPGKLLKPALVDLIFVNQKPVEPIRASSSSRSSRSTRRSSSTKPSRRSSSRSRRSSSRSRRSSSRSRRSSSRSRRSSRRSTSRSRSLSKRSIRNISTVGDLEDLVASNLPIAIPESLSRSLSPSRTDFHEAEIELGSDFDLNNLPENRIAELKQLNVLAKQNGFRMINVPLDGNCMFSVIGRAFNTSSSVIRQHTVDYLRRCKGSFDHIPANIDDPTINWNDYIDRLEEDACWGDNTALFAASLALNFQAHILQVAGGDEGSWIRFGVNETNMGRIVNMGYLDNFHYIALEPFSGRLDILSIPSTHSKCPPPEISNRRDEEIRRDEEVEDEVIGERIVREAEVIERELRQEEELTSIVSTKRSLRPSIPPKISTEHRRTPKLRPSVPRPSSIRQSQPNVAALARLETLTKIKDIIDALQRPLENKLSTLTNTEKAIMQCIGVA
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
What are the official names of this protein?
Putative ubiquitin thioesterase 232R.
Protein: Y2343_KLEP7
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPASNPRLRAAVDKALSNNMTRDTLNRAIARGVGGDEDANMETIIYEGYGPGGTAVMVECLSDNRNRTVAEVRHAFTKTGGNLGTDGSVSYLFSKKGVISFEKGDEDTIMEAALEAGAEDVVTYDDGAIDVYTAWEEMGAVRDALEAAGLKADAAEVSMIPSTKADMDAETAPKLLRLIDMLEDCDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein KPN78578_23430.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.