PharMolix/UniProtQA huggingface dataset:
Protein: CHS1_CAMSI
Sequence: MVTVEDIRRAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKAELKEKFKRMCDKSMIKKRYMYLTEEILKENPQVCEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGSDPIPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVELKLGLKEEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAADGLKTTGEGLEWGVLFGFGPGLTVETVVLHSLST
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 1, Naringenin-chalcone synthase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: XNI_ALIF1
Sequence: MAIHLVIIDALNLIRRVHSAQPNQDDIQAVITTTTRTINKILKETEPTHIIAVFDHHLQDRGWRAEILPQYKEDRKPMPEALQKGMDDIQEAWWKLGIDSLLSDGDEADDLVATLANKVAMHNEQVTIISTDKGYCQLLSPTLRIRDYFQHRWLDAPFVEKEFGLKPEQLADYWGLAGISSSKITGIPGVGPKAALEILTQFPTIEAANESEDLPKKYRKKFDEHYETAILCRQVAGLRTDIELGFNLQDIRYEKGTRD
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: DRP3B_ARATH
Sequence: MSVDDLPPSSASAVTPLGSSVIPIVNKLQDIFAQLGSQSTIALPQVAVVGSQSSGKSSVLEALVGRDFLPRGNDICTRRPLRLQLVQTKPSSDGGSDEEWGEFLHHDPVRRIYDFSEIRREIEAETNRVSGENKGVSDIPIGLKIFSPNVLDISLVDLPGITKVPVGDQPSDIEARIRTMILTYIKEPSCLILAVSPANTDLANSDALQIAGNADPDGHRTIGVITKLDIMDRGTDARNHLLGKTIPLRLGYVGVVNRSQEDILMNRSIKDALVAEEKFFRSRPVYSGLTDRLGVPQLAKKLNQVLVQHIKALLPSLKSRINNALFATAKEYESYGDITESRGGQGALLLSFITKYCEAYSSTLEGKSKEMSTSELSGGARILYIFQSVFVKSLEEVDPCEDLTADDIRTAIQNATGPRSALFVPDVPFEVLVRRQISRLLDPSLQCARFIFDELVKISHQCMMKELQRFPVLQKRMDEVIGNFLREGLEPSQAMIRDLIEMEMDYINTSHPNFIGGTKAVEQAMQTVKSSRIPHPVARPRDTVEPERTASSGSQIKTRSFLGRQANGIITDQAVPTAADAERPAPAGSTSWSGFSSIFRGSDGQAAAKNNLLNKPFSETTQEVYQNLSTIYLKEPPTILKSSETHSEQESVEIEITKLLLKSYYDIVRKNVEDLVPKAIMHFLVNYTKRELHNVFIEKLYRENLIEELLKEPDELAIKRKRTQETLRILQQANRTLDELPLEAESVERGYKIGSEAKHEELPGTRRSRTETNGNGRLHM
What is the function of this protein?
Involved in the control of mitochondrial and peroxisomal division and morphology.
What are the official names of this protein?
Dynamin-related protein 3B, Dynamin-like protein 2b.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Mitochondrion. Peroxisome.
Protein: RS10_MYCA1
Sequence: MAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RS12_NEIM0
Sequence: MPTINQLVRKGRQKPVYVNKVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTAGVKDRKQARSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NIA_CHLVU
Sequence: RPPVTEVESQNYYHFHDNRVLPSHVDEALANSEGWWYKPDFIINDLNVQSAIGYPAHEEVVPLVAGTYAVRGYARGHGNKIIRCEVSLDDGKSWRLGSVTHEGQPTEYGKHWGWVWWSLEVPIAELLTTPEIICRAWDSSMNTQPNTFTWNVMGMMNNCCYRVKIHPRQTTDGRFALQFEHPTIAGPTVGGWMNRAEDVAAAAAVTVAPPPAPAGAKSFTMAEVETHTTMESAWFVVDGKVYDATPFLKDHPGGADSILLVAGIDATDEFNAIHSLKAKKQLLEYYIGELAEEGQEAAASDRATPGPAAAIGTAVPVA
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: NCAP_LNYV3
Sequence: MTTSAEKLAKLEQLRKERAAVIQKPTTQVSSEPVVTEKPRVRNTAYDSLAGVTIGKRASRKWSDADIKSIPIYDVHQVPAAQVIALGKDLLTQIQNNSVNTVTVDYCLVLAVSIPKPAMTSFEHLLTPPSPEQGTRLDFTQPQAGVSNRSGLTAIEKMTLNATRKNLLTETDEEKRARYEAIIKKMEDQEAGLGTSKATVVTSETEAAAYGFLAATLLKLYAKSTESYVAGLAQIRNRFAAWYDCPKAVLDAFQPTEAALVSLRAAFARRPEVLSTWTLWVAVNENRTPGLLVTQQGLLNYLACQQFAYPGMHAYTLLIEIHEHTGMKFSDLLVEMDCPATRAGVREALELIRDYEITKDHPKRTTYFRYARNWDPKYFGALQSTECKTLVYVAASVSKKVSAQGANGDPMEIFAIKNLDATIKARLDPVAENMAGKILDQMLMDEMSGASWATKASTQ
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the cytorhabdovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: METE_STAAB
Sequence: MTTIKTSNLGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLYDHILDTSLLFNIIPERFQGRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWDNVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSKGGHQTFEEKVKTLLPLYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKASVAKKLVIQTYFERAHLKFLSSLPVGGLGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDIEAKKVLIDKLLAHTNELVIQPSSSLLHVPVSLDDETLDTSVGEGLSFATEKLDELDALRRLFNQNDNFKYDKLKARYERFQNQSFKNLDYDFESVRTSRQSPFAQRIEQQQKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGLDVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDETVYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQVDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDLDADVISIETSRSHGDLIKDFEDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQIDRSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: Y117_METBU
Sequence: MDDLEAIRQKRLAELQQQQSSPQNDAQAAYQQEQAQAERDEQVKAVLRQVMTPEARERLTRLRLSRKELVEQLESQLVMLAQNGRLQTKIDDEKLKVLLTQMQPQKRQTSITRM
What are the official names of this protein?
DNA-binding protein Mbur_0117.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: R10AB_DROME
Sequence: MASKVSRDTLYEGVNGLLEASAKKKRGFLETVELQIGLKNYDPQKDKRFSGTVKLKHIPRPKMKVCILGDQQHCDEAKANNVDFMDAEALKKLNKNKKLVKKLAKSYDAFLASESLIKQIPRLLGPGLNKAGKFPALLSHQESMIGKIEEVKSTIKFQMKKVLCLSVAVGHVGMKSDELAQNVNLSINFLVSLLKKNWQNVRSLHVKSSMGPPQRLY
What are the official names of this protein?
60S ribosomal protein L10a-2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NU2C_MICAN
Sequence: MDFSSLVASQLNAGVIWPEGILIITLMVILIGDLIVGRSARSWLPYVAIAGLLAAVVALYFTWDNPKPVAFLGAFEGDNLSIVFRAIIALSTASTVLMSIRYVEQAGTSLAEFLAIMLTATLGGMFLSGASELVMIFISLEMLSISSYLMTGYMKRDPRSNEAALKYLLIGASSSAIFLYGVSLLYGLSGGETSLSAIAQKLTDVNGGQSLALAIALVFVIAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTVFGLVSEQWRFIFIALAILSMILGNVVALAQTSMKRMLAYSSIGQAGFVMIGLTAGTDAGYSSMIFYLLIYLFMNLGAFACVILFALRTGTDQIAEYSGLYQKDPLLTLCLSICLLSLGGIPPLAGFFGKIYLFWAGWQAGLYALVLVGLVTSVASIYYYIRVVKMMVVKEPQEMSDAVKNYPVINWTLTGMRPLQVGIVLSLVATSLAGILSNPLFTLATDSVTTTPILQSAALATHISRAN
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: C81F1_ARATH
Sequence: MLYFILLPLLFLVISYKFLYSKTQRFNLPPGPPSRPFVGHLHLMKPPIHRLLQRYSNQYGPIFSLRFGSRRVVVITSPSLAQESFTGQNDIVLSSRPLQLTAKYVAYNHTTVGTAPYGDHWRNLRRICSQEILSSHRLINFQHIRKDEILRMLTRLSRYTQTSNESNDFTHIELEPLLSDLTFNNIVRMVTGKRYYGDDVNNKEEAELFKKLVYDIAMYSGANHSADYLPILKLFGNKFEKEVKAIGKSMDDILQRLLDECRRDKEGNTMVNHLISLQQQQPEYYTDVIIKGLMMSMMLAGTETSAVTLEWAMANLLRNPEVLEKARSEIDEKIGKDRLIDESDIAVLPYLQNVVSETFRLFPVAPFLIPRSPTDDMKIGGYDVPRDTIVMVNAWAIHRDPEIWEEPEKFNPDRYNDGCGSDYYVYKLMPFGNGRRTCPGAGLGQRIVTLALGSLIQCFEWENVKGEEMDMSESTGLGMRKMDPLRAMCRPRPIMSKLLL
What is the function of this protein?
Involved in indole glucosinolate biosynthesis.  Catalyzes hydroxylation reactions of the glucosinolate indole ring.  Converts indol-3-yl-methylglucosinolate (I3M) to 4-hydroxy-indol-3-yl-methylglucosinolate (4OH-I3M) and/or 1-hydroxy-indol-3-yl-methylglucosinolate (1OH-I3M) intermediates.  These hydroxy intermediates are converted to 4-methoxy-indol-3-yl-methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl-methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2).
What are the official names of this protein?
Cytochrome P450 81F1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NEF_HV196
Sequence: MGGKWSKSSIVGWPAIRERMRRARPAADRVGTQPAADGVGAVSQDLARHGAVTSSNTSHNNPDCAWLEAQEEEEVGFPVRPQVPLRPMTYKAAFDLGFFLKEKGGLDGLIYSKKRQEILDLWVYHTQGFFPDWQNYTPGPGIRYPLTFGWCYKLVPVDPAEVEETTEGEDNCLLHPINQHGMEDEHREILMWKFDSSLARRHVARELHPDYYKDC
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Virion. Secreted. Host Golgi apparatus membrane. Note=TGN localization requires PACS1. Associates with the inner plasma membrane through its N-terminal domain. Nef stimulates its own export via the release of exosomes. Incorporated in virions at a rate of about 10 molecules per virion, where it is cleaved.
Protein: RS10_AQUAE
Sequence: MEQEKIRIKLRAYDHRLLDQSVKQIIETVKRTGGVVKGPIPLPTRKRKWCVLRSPHKFDQSREHFEIREFSRILDIIRFTPQTIEALMEISLPAGVDVEVKMRG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RNZ_METKA
Sequence: MDRELVMRFLGTGGAVPSKDRSHPGLLVEFSGTKLLIDCGEGTQRRAMEQGVTIHDVDAVLLTHHHVDHVAGLLPLATTVDLLHGRRLKVYGPTAGSESALDISDLEVIEYREVNPGDEVEIGDLRVLVYESEHGVPTVDYRIETPKIPGKADPKYIRRVPPSKRREVLLRGERPYSLTKPGKISVYVKGDGRPADPENVRGCQVLVHEACFEDHEEAVRYLHSTHLEAAEVAREAGVDLLVLTHLSTKVDPERMREEAREVFPVVVVARDGLMVRVRR
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: PHOCN_CAEEL
Sequence: MTAATENRTVRRNGPGTKRADWNNWSPLAFEEMDSALNIQQYIQQTIKANPADVATILTPPLDQDEGVWKYEHLRQFCIELNGLALLLQRECIPETCQQMTATEQWIFLCAAHKNPNECPAIDYTRHTLDGAATLLNSNKYFPSRVNIKEISISKLGSVARRVYRIFSHAFFHHRKLFDEFENETHLCKRFTTYVSKYNLMQQEHLIVPILPNQQQQQQTTVQ
What is the function of this protein?
May play a role in membrane trafficking, specifically in membrane budding reactions.
What are the official names of this protein?
MOB-like protein phocein, Mps one binder 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
Protein: RL27A_SCHPO
Sequence: MVKILKPGKVALITRGRFAGKKVVILQAIDQGSKSHPFGHAVVAGVERYPLKVTKSMGAKRIARRSRVKPFIKVVNYNHLMPTRYALELDNLKGLITADTFKEPTQRSAARKTVKKTFEEKYQSGKSAWFFTPLRF
What are the official names of this protein?
60S ribosomal protein L27-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL27 family.
Protein: CMPB_SYNE7
Sequence: MVTARETRRNGSRPSGLKKWRQKLDGILLPLAGILGFLIIWQIFSSSGATRLPGPLSLFTEERTRELLLYPFLDRGGLDKGLFWQTIASLTRVAQGFSIAAIIGISVGILVGLNRQLNAMLDPLFQFLRMIAPLAWVPIALVAFQQNQPAAIFVIFITAVWPILINTAEGVRQIPQDYNNVARVLRMSKSKYLMKVVLPAALPYIFTGLRIAIGLSWLAIIAAEIVMSGIVGIGFFIWDAYQQNYVSDIILAVIYIGAVGLLLDRFVAWLQRWILRNM
What is the function of this protein?
Part of the ABC transporter complex CmpABCD involved in bicarbonate transport.  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Bicarbonate transport system permease protein CmpB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL25_BACVZ
Sequence: MATLKANERTDFKRSTLRKIRHSGHVPGIIYGKEITNTPVSLDSVELLKTLRDEGKNTIITIDVNGNQQSVMVTDLQTDPLKNELTHADFQVVNMSEELEAEVPIQLTGEAKGVKDGGVIQQPLHELSIKAKPKDIPQTINVDISGLEMNDVLTIADLTADGNYTFTNDPEEVVASILPPKQEAFEEDAEPSPGEEPEGENQ
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ATPE_DEHM1
Sequence: MAKLKLDIVTAERSVFSEEVDLVVAPGIEGEMAILPHHAPLMTALQAGELKAKIGSEEYSMVVSGGFLEVRPDRVIVLADSAERAEEIDIARATEAKKRAEARMADKYEPGMLAAETEASLRRAMIRLKVAEKRRKRPSV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: METE_ALIF1
Sequence: MTTESKTKTVTHILGYPRVGAQRELKFAQEKYWRGEIEQKELLAVGSELRQRHWKDQSASGLDFVTAGDFAWYDHVLTTSLLLGHVPARHNNGFPDLDTLFKVGRGQSQNSCGCGEAASDMTKWFNTNYHYIVPEFSKNDKFNVSWSQLFDEIAEAQKQGHNVKPVLLGPLSYLWLGKEVNDEEVEQGFDRLSLLPRLLTAYQAIFSKLSALGVEWVQIDEPILALELPKAWADSFKLAYQVIQSDVKLLLTTYFDGVEHHLDKITKLAVNGLHIDVSAAPDQLDAIVSALPKEWVLSVGAVNGRNVWRADLERLHERLQPVKEALGDKLWIASSCSLLHSPVDLDQETELSKETLQWFAFAKQKLREVTLLADALDGNQNAILACHQYSQPLRERESAEHINKPAVQQRLAAITPALAERAEAYSVRAQHQAEKLGLPLLPTTTIGSFPQTSDIRQQRSAYRTGKLNEQDYVTAMKGHIADAVERQERLDLDVLVHGEAERNDMVEYFAENLNGFQATRFGWVQSYGSRCVKPAIVVADIEREAPITVSWTQYAQSLTTKQMKGMLTGPVTILGWTFPREDITRKEIAQQLALVLRDEVSDLQQAGINIIQIDEPAIREGLPIKKSDQKAYLDWAVEAFKISAASAKSETQIHTHMCYSEFNEIIESVAALDADVITIETSRSNMELLKAFEDFNYPNEIGPGVYDIHSPNIPSQEWIVDLIETAAARVPVERLWVNPDCGLKTRNWKETEAALENMVKAAKALRKKWQSNAA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: GDL19_ARATH
Sequence: MMAKNCNLVSVLCVFLVLTLFNKPITVAGQNIPAVGLFTFGDSNFDAGNKQTLTKTLLPQTFWPYGKSRDDPNGKFSDGLIAPDFLAKFMRIPIVIPPALQPNVNVSRGASFAVADATLLGAPVESLTLNQQVRKFNQMKAANWNDDFVKKSVFMIYIGANDYLNFTKNNPNADASTQQAFVTSVTNKLKNDISLLYSSGASKFVIQTLAPLGCLPIVRQEFNTGMDQCYEKLNDLAKQHNEKIGPMLNELARTAPASAPFQFTVFDFYNAILTRTQRNQNFRFFVTNASCCGVGTHDAYGCGFPNVHSRLCEYQRSYLFFDGRHNTEKAQEMFGHLLFGADTNVIQPMNIRELVVYPADEPMRESWVPPTSATVQLRESRGYEYY
What is the function of this protein?
Involved in the control of the PYK10 complex size and possibly substrate specificity.  May be exported from the endoplasmic reticulum upon interaction with MVP1.
What are the official names of this protein?
Inactive GDSL esterase/lipase-like protein 23, GDSL-like lipase 23, Probable myrosinase-associated protein GLL23.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Note=Only transiently resident in a specific ER subcompartment and is either post-translationally modified prior to export or targeted for degradation.
Protein: FTSY_STRMU
Sequence: MGLFNRLFGKKRQEEKSTTDSIEEAAEQEVTQEKPALLAETAETAESQQSVYEKDVTESQAEQVSDARIIEDGQNSKEPAASGHSVQEHKQQPVQHQQEVFHSENSVAAVQNNTETMPSQQKKDEKPNQSPDFMAEYYARKAELAQKVESQKPAETAEQESQTTLSDQKETETAVNQSEEEASSQIAESVESEEEKYNRSLKKTRTGFGARLNAFLANFRNVDEEFFEDLEEMLILSDVGVQVASTLTEDLRYEAKLEKAKKPEALRRVIIEKLVDIYDKDGQFNEKINFQNDLTVMLFVGVNGVGKTTSIGKLAYKYKHQGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPKNADPASVVYDGVERAVAADVDILMIDTAGRLQNKDNLMAELEKIGRVVKRVIPDAPHETLLTLDASTGQNALVQAKEFSKITPLTGLILTKIDGTAKGGVVLAIRQELAIPVKFIGFGEKIDDIGEFHSEDFMRGLLEGLL
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: SDE2_DANRE
Sequence: MELFVISPDLKFNNLTVAPDSTVSDLIDHFTVKNGVSLTDFYVSSNGRLSRSNDLLQSGVVYRLEPRLCGGKGGFGSMLRALGAQIEKTTNREACRDLSGRRLRDVNHEKEMAEWLKKQADREAEKEQRRLERIQRKLAEPKHYFTDTNYEQQCHDLSERLEDSVLKGMQASSSGLVQADEGPSLKRANPTDSKKKAKKKCYWTGMAGLEEMASSSEGSDDSDSEVSPSTSGASCSSGFPKPVVSAHKADPQEQPSSSSPAQRKHNQEELQKRDKEECTSEISSSSSSPAANNEKLNQEETNEISSSSSSPAPKPTEVNQQEMETEMECTAQISSSSSSPAEHSEEEVQQTAERVEKMAEEVQKTAEEVQKKTEESTAEISPSSSIPEEKSQVLSQVEDPLDLLSVSGPEQLEALGLERLKKELMERGMKCGGTLQERAARLFSVKGLTPDQIDPSLLAKPSKGKKK
What is the function of this protein?
Plays a role in ribosome biogenesis by enabling SNORD3- and SNORD118-dependent cleavage of the 47S rRNA precursor (By similarity).  Binds ncRNA (non-coding RNA) including the snoRNAs SNORD3 and SNORD118 (By similarity).
What are the official names of this protein?
Splicing regulator SDE2, Replication stress response regulator SDE2.
What is the protein family that this protein belongs to?
Belongs to the SDE2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGM_RHIRD
Sequence: MIKTIKTTPYQDQKPGTSGLRKKVPVFAQENYAENFIQSIFDALEGFEGQTLVIGGDGRYYNREVIQKAIKMAAAAGFGKVLVGQGGILSTPAASNVIRKYKAFGGIVLSASHNPGGPTEDFGIKYNIGNGGPAPEKITDAIYARSKVIDSYKISDAADIDLDKIGSFKVDELTVDVIDPVADYAALMEELFDFGAIRSLIAGGFKVVVDSMSAVTGPYAVEILEKRLGAPKGSVRNATPLPDFGGHHPDPNLVHAKELYDDVMSPEGPDFGAASDGDGDRNMVVGKGMFVTPSDSLAIIAANAKLAPGYAAGISGIARSMPTSAAADRVAEKLGLGMYETPTGWKFFGNLMDAGKVTICGEESFGTGSNHVREKDGLWAVLYWLNIVAARKESVKDIVTKHWAEYGRNYYSRHDYEEVDSDAANTLVAILREKLATLPGTSYGNLKVAAADDFAYHDPVDQSVSKNQGIRILFEGGSRIVLRLSGTGTAGATLRLYVERYEPDAARHGIETQSALADLISVADTIAGIKAHTADSEPTVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.  Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide.
What are the official names of this protein?
Phosphoglucomutase, PGM, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NOS3_MOUSE
Sequence: MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSQAPAPPSPTRPAPDHSPPLTRPPDGPRFPRVKNWEVGSITYDTLSAQAQQDGPCTSRRCLGSLVFPRKLQSRPTQGPSPTEQLLGQARDFINQYYNSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRTAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLIRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFTLPPEMVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSEIGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAARDIFSPKRSWKRQRYRLSTQAESLQLLPGLTHVHRRKMFQATILSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSTEPVAVEQLEKGSPGGPPPGWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYEEWKWFSCPTLLEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSAPSAHPGEIHLTIAVLAYRTQDGLGPLHYGVCSTWMSQLKAGDPVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPFRGFWQDRLHDIEIKGLQPAPMTLVFGCRCSQLDHLYRDEVLDAQQRGVFGQVLTAFSRDPGSPKTYVQDLLRTELAAEVHRVLCLEQGHMFVCGDVTMATSVLQTVQRILATEGGMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWSFDPPGPEIPGS
What is the function of this protein?
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway.  NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.  May play a significant role in normal and abnormal limb development.
What are the official names of this protein?
Nitric oxide synthase, endothelial, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, eNOS, NOS type III, NOSIII.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
What are the subcellular locations of this protein?
Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Cell membrane. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle, which is favored by interaction with NOSIP and results in a reduced enzymatic activity.