PharMolix/UniProtQA huggingface dataset:
Protein: WDR37_MOUSE
Sequence: MPTESGSCSTARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIDTLNERLAGEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK
What is the function of this protein?
Required for normal ER Ca2+ handling in lymphocytes.  Together with PACS1, it plays an essential role in stabilizing peripheral lymphocyte populations.
What are the official names of this protein?
WD repeat-containing protein 37.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EFP_MYCBP
Sequence: MATTADFKNGLVLVIDGQLWTITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKVDTATVDRRDTTYLYRDGSDFVFMDSQDYEQHPLPEALVGDAARFLLEGMPVQVAFHNGVPLYIELPVTVELEVTHTEPGLQGDRSSAGTKPATLQTGAQINVPLFINTGDKLKVDSRDGSYLGRVNA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAP_PSEAE
Sequence: MSNKNNLRYALGALALSVSAASLAAPSEAQQFTEFWTPGKPNPSICKSPLLVSTPLGLPRCLQASNVVKRLQKLEDIASLNDGNRAAATPGYQASVDYVKQTLQKAGYKVSVQPFPFTAYYPKGPGSLSATVPQPVTYEWEKDFTYLSQTEAGDVTAKVVPVDLSLGAGNTSTSGCEAEDFANFPAGSIALIQRGTCNFEQKAENAAAAGAAGVIIFNQGNTDDRKGLENVTVGESYEGGIPVIFATYDNGVAWSQTPDLQLHLVVDVVRKKTETYNVVAETRRGNPNNVVMVGAHLDSVFEGPGINDNGSGSAAQLEMAVLLAKALPVNKVRFAWWGAEEAGLVGSTHYVQNLAPEEKKKIKAYLNFDMIGSPNFGNFIYDGDGSDFGLQGPPGSAAIERLFEAYFRLRGQQSEGTEIDFRSDYAEFFNSGIAFGGLFTGAEGLKTEEQAQKYGGTAGKAYDECYHSKCDGIANINQDALEIHSDAMAFVTSWLSLSTKVVDDEIAAAGQKAQSRSLQMQKSASQIERWGHDFIK
What is the function of this protein?
A secreted aminopeptidase.  Acts on free N-terminal amino groups with a very strong preference for Leu- followed by Met- and Ala-, and no activity on Glu- or Gly- peptides (an exhaustive analysis was not performed).  Both the AP56 and AP28 forms have activity.
What are the official names of this protein?
Aminopeptidase, Leucine aminopeptidase, PaAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28A subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DCUP_ECO8A
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DP2S_HALSA
Sequence: MPLEPSVRVVRELTSRGYNADREAVTLLAGADDPGAAVERAVAAAAADAATLTVSDVRAVLDAHTASSAAQTSAPASTPPDEATTHTDPSATDTPPNHDGGRAATADARSVEIDGDMTGASTGTGEYQDFVSVFRDRYDRLAAQLRGRVNHRPTSALASMPGGSDAAIVGMVNDIRSTTSGHWRVELEDTNGVFPVLVLKDRDVSDLVDDLLLDEVIAVSGTLADDGTILFADDIYFPEVPRTYSPSTADRSVQAALISDVHVGSQEFAADAWRSFADWLHTPAAESVEYLLIAGDMVEGVGVYPGQDEELDIVDIYDQYETFAEHLKDVPGDMEIVMIPGNHDAVRLAEPQPAFDEELRSIMRAHDARITSNPSTVTIDGVSVLLYHGVSLDEVIAEHPSDDVTYDDPQNAMELLLKKRHVAPPFGGRTRLAPEAEDHLAIDTVPDVFHTGHVHKLGVGIHHNVRLVNSGCWQHQTAFQESVNISPDVATAPILDLDTLDITVHKFS
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II small subunit, Pol II, Exodeoxyribonuclease small subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase delta/II small subunit family.
Protein: WBP11_HUMAN
Sequence: MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL
What is the function of this protein?
Activates pre-mRNA splicing.  May inhibit PP1 phosphatase activity.
What are the official names of this protein?
WW domain-binding protein 11, WBP-11, Npw38-binding protein, NpwBP, SH3 domain-binding protein SNP70, Splicing factor that interacts with PQBP-1 and PP1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
Protein: WTR18_ARATH
Sequence: MARKYFQREVLPVTALVIMECANVGLNTLFKAATLKGMSFHVFIVYSYGLAALLLLPSLFCSFRSRTLPPMNFSILYKIVLLGIIGCCSNIMGYTGINYSSPTLASAISNLTPAFTFLLAVVFRMESVSFKRTSSVAKMLGTVVSIGGAFIVTLYNGPVVIAKSPPSVSLRSQSTNPNWILGAGFLAVEYFCVPLWYIVQTQIMREYPAEFTVVCFYSIGVSFWTALVTLFTEGNDLGAWKIKPNIALVSIVCSGLFGSCINNTIHTWALRIKGPLFVAMFKPLSIAIAVAMGVIFLRDSLYIGSLIGATVITIGFYTVMWGKAKEVALVEDDNKANHEEANEADLDSPSGSQKAPLLESYKNDEHV
What are the official names of this protein?
WAT1-related protein At3g28050.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIS4_RHOP5
Sequence: MILFPAIDLKNGQCVRLEQGDMDRATVFNLDPAAQAASFAAQGFEYLHVVDLDGAFAGKPMNAQAVEAMLKVVKMPVQLGGGIRDLATIEAWLGKGVTRVIIGTAAVRDPALVKEAAKQFPGRVAVGLDARDGKVAVQGWAETSTVTALEIAQRFEDAGVAAIIFTDIARDGLLKGLNLDATIALAEAISIPVIASGGFASIDDVKALLEPRAKKLEGAIVGRALYDGRLDPAEALALIGRAAAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUL4A_MOUSE
Sequence: MADEGPRKGSVSALMGRTNGLTKPAALAGGPAKPGGTGGSRKLVIKNFRDRPRLPDNYTQDTWRKLHEAVKAIQSSTSIRYNLEELYQAVENLCSHKVSPTLYKQLRQVCEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDRMVQSKTIDGILLLIGRERSGEAVDRSLLRSLLSMLSDLQVYKDSFELKFLEETNCLYAAEGQRLMQDREVPEYLNHVSKRLEEEADRVITYLDHSTQKPLIACVEKQLLGEHLTAILQKGLEHLLDENRVPDLTQMYQLFSRVKGGQHALLQHWSEYIKTFGTTIVINPEKDKDMVQDLLDFKDKVDHVVEVCFQRNERFINLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERILDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSAPGPIDLTVNILTMGYWPTYTPMEVHLPPEMVRLQEVFKTFYLGKHSGRKLQWQTTLGHAVLKADFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNADFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDSPNQYHYVA
What is the function of this protein?
Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins.  As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.  The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1.  The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component.  DCX(DET1-COP1) directs ubiquitination of JUN.  DCX(DDB2) directs ubiquitination of XPC.  DCX(DDB2) ubiquitinates histones H3-H4 and is required for efficient histone deposition during replication-coupled (H3. 1) and replication-independent (H3. 3) nucleosome assembly, probably by facilitating the transfer of H3 from ASF1A/ASF1B to other chaperones involved in histone deposition.  DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of p53/TP53 in response to radiation-induced DNA damage and during DNA replication.  DCX(DTL) directs autoubiquitination of DTL.  In association with DDB1 and SKP2 probably is involved in ubiquitination of CDKN1B/p27kip.  Is involved in ubiquitination of HOXA9.  The DDB1-CUL4A-DTL E3 ligase complex regulates the circadian clock function by mediating the ubiquitination and degradation of CRY1.  A number of DCX complexes (containing either TRPC4AP or DCAF12 as substrate-recognition component) are part of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  With CUL4B, contributes to ribosome biogenesis.  The DCX(AMBRA1) complex is a master regulator of the transition from G1 to S cell phase by mediating ubiquitination of phosphorylated cyclin-D (CCND1, CCND2 and CCND3).  The DCX(AMBRA1) complex also acts as a regulator of Cul5-RING (CRL5) E3 ubiquitin-protein ligase complexes by mediating ubiquitination and degradation of Elongin-C (ELOC) component of CRL5 complexes.
What are the official names of this protein?
Cullin-4A, CUL-4A.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: SYT_NAUPA
Sequence: MQQDVIALKIDDKIIDLQTAEAQGIEGGEPVYFDNSPEALEVIRHSAAHLMAQAIKELYPEAKFYVGPTIENGFYYDLKTETPITDKDLKNIEKKMKALAKKKFDITRYEISMEEAREKFKNDELKQAVLDMIPGDTVSIYKQGDFEDLCRGPHVPNTKYLHNVKLQKVAGAYLGGDSKNEMLTRVYGTAFATKEALQEYLKMLEEAAKRDHRKLGTELELWMFDEEVGAGMPIWLPNGALLRGNLEKLLYSAHIRREYLPVRGPELLRSHMWKISGHYYNYKENMYFTEIENDDPEKPADEYGIKPMNCLAHVKIFGHKVRSYKELPLRLFEFGTVHRHEKSGVLHGLLRVREFTQDDAHIFCRPDQIEEEVIKVLEFVDSIMERFGFNYEMEISTRPEKSIGSDEIWEKATESLKKALNSLNREYGIDEGGGAFYGPKIDIKITDAIGRKWQCGTIQVDFNLPERFDITYVDENNERVRPVMIHRAIIGSFERFIAILTEHYAGEFPTFIAPIKAIFVPIAESHVEYAKKLQKELLEADINTEIFASNDSLNKRIRNAEKRRVGYVVIIGDEEVETGTVAIRDRKKREQYKMTKGEFVEMIKNLSEVKL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_LACP3
Sequence: MSKAITDVFYTAFKTALPLTSSPLVQCITNEITVESMANALLYIDAKPVMADDQREFPEFFAQSDALLLNLGHISEVRQQNLLAAGKFAQATNQPTVIDLVGVSATQLRYDLGHQLLVNHPNVVKGNISEMRRFADLKSTGRGVDGSQLDQSVTALGELAASLQQLTQAFPTTTFLATGKIDLVVSAKGTWYLKNGVPQLDRFTGTGDIVGALIAALLGTGLDNDAAVVVAVSYFNCCGEVAAAQNRTGGLAAFREGTLNQLSLLAATADWLQMVKGEAL
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RS4_PARMW
Sequence: MARYRGPRLRITRRLGDLPGLTRKAAKRSYPPGQHGQARRKRSEYAIRLEEKQKLRFNYGVSERQLVRYVKKARAQEGSTGTNLLKLLENRLDNVCFRLGFGPTVPGARQLVNHGHVTVNGRVTDIASYQCKPGDVVAIRERKCSKQLAEGNLEFPGLANVPTHLELDKAKLSAKVTGRCEREWVALEINELLVVEYYSRKV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS7_GEMAT
Sequence: MSRRKSAVKRTILPDARYDSQTVSKFINSLMIQGKKSTAEGIFYGAMDIVEAKTSQPGVGVFKQALNNLKPVVEVKSRRVGGATYQVPVEVRQDRRTALAMRWLISYSRDRNEKSMKEKLAAEVLAASRGEGNAVKKKEDTHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TYSY_HUMAN
Sequence: MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Protein: YNFA_ECOK1
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALIWLRVVDGVKLTLYDWTGALIALCGMLIIVAGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CALK_PENDC
Sequence: MSSPIQTAIVQTSETSAARLPLRVDRSAPIPQVKSEHHVLVRVLAVALNPNDHKMVTHFNMPDSIAGCDFCGIVTESSSNGTSLSSSAGARLPVGTRVCGALFPYSPEDPDNGSFAQYCVVDARLLVRVPDSWSDLEAASLGVGWSTISLAFSDPNALGLEGLPTQPSHRAKEPVLVYGGGTASGTLACQLLNLMGYTPIAIASNQSSELAMKYGASATACYTSKDCVDTVKSLAGKPIRRILDCITDAESAAICYSAMARSSGTYACLEECPDACRTRRIIKVKEVMGFQVLGVDIKLGDSTYTRLGDQKLMAIGIQWANEIQALMESGQLKAHPLRELPGGWEAIIEGLEMLRNGEVRGQKLVVRIPQE
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of calbistrin A and related compounds.  Calbistrin A is a secondary metabolite with an interesting structure that was recently found to have bioactivity against leukemia cells.  It consists of two polyketides linked by an ester bond: a bicyclic decalin containing polyketide and a linear 12 carbon dioic acid structure (PubMed:30598828).  The polyketide synthase calA is probably responsible for forming the decalin moiety.  Because calA lacks a designated enoylreductase (ER) domain, the required activity is provided by the trans-enoyl reductase calK (PubMed:30598828).  Following release from the PKS, calF then probably catalyzes the oxidation and the subsequent Diels Alder cycloisomerization that lead to the formation of the decalin moiety (Probable).  The decalin polyketide backbone includes two C-methyl groups, at C7 and C11 in backbone, of which the C7 position is probably methylated by the methyltransferase domain of calA.  A candidate for adding the methyl group at C11, if not done by CalA, is the cluster methyltransferase calH (Probable).  Several additional tailoring enzymes within the cluster could be involved in the modification of the decalin polyketide product.  Those include the 3 cytochrome P450 monooxygenases CalE, CalG and CalL, of which one might be responsible for the introduction of the extra hydroxyl group attached to the backbone of the decalin moiety, at position C9 in the backbone, that allows for attachment of the linear moiety (Probable).  One tailoring enzyme activity that is expected to be involved in biosynthesis of calbistrin is an acyltransferase for connecting the two polyketide synthase products, and which could be performed by the cluster acyltransferase calJ (Probable).  The enzyme responsible for the biosynthesis of the linear moiety, probably a second PKS, has not been identified yet (Probable).
What are the official names of this protein?
Trans-enoyl reductase calK, Calbistrin biosynthesis cluster protein K.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: YGZ2_SCHPO
Sequence: MHRAAAVDTTPKIVFYYKCLLNKNWNEPINNIFWGEFFLLQPRLEVLSQLLRECPKQELTVNGPKFHSMYLYISEILKSKAESLRIRNSLATLQTFLAELSVRKPTDVNFTIFLLLGNIDSIDIQFSAFIKNLCQLVKDSEDVQSVEISLRFVLHFVSFLYNSSFISHIYGNYDVFSTLYTVILKRKFGFETAVYAIGLLSACDKFETVNTFRLGLSKIVDEEFFSSVLSSSAQQLISLRDFYVSIKPDNPLTGSFFNLFSLRSSSNNPDSDQESQFSRLPDERATMFFTIYELCCCNKLFLKKLVEGGEKNGEAPLEALLSLLSYINTHQRQSERSHHFSILSLILFHIIIDDRSLLYRLTDKKFKISVRVCSQRYPYPPNATKPATPLGYMLDICCIGIQHNMKLNLSATMYFLYFSFVYRAMTSLVQDGIRMEYHWLELWRVLFSFLDFVSVLINTSPTEDVTRLLELILDVLAYIISNGDALVIRSDELVDLFYKLLHSSKNFSSFSSKIPDERLGALNYLLEVTEYLTSKTVDLPRSTADEVESVIKLELESIPVAKQNAFGGVPPFKESQYRLFHKRASRGMADLLRRKSEAAN
What are the official names of this protein?
UPF0588 membrane protein C20F10.02c.
What is the protein family that this protein belongs to?
Belongs to the UPF0588 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: URE2_PSEPG
Sequence: MIPGEVQVAAGDIELNSGRETVSATVANHGDRPVQVGSHYHFFEVNEALVFDRAPTLGFRLDIPAGTAVRFEPGQARTVQLVAYAGKREVYGFQGKVMGALEGRA
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_WIGBR
Sequence: MHFNNKNKSLDCLNTKIWPSPAKINLFLSVTGIRKDGYHFIQTLFQFLNYGDYLIFNTTSDKKIKLINKIHGIRNENNLIIRAAKSLKDFMWKNKNHDTPGVKIFIKKYIPIGGGLGGGSSNAATTLIALNEHWKCKLSLNTLADLGLQIGIDIPVFIYGKSAFAEGIGEKLSLFQPKEKFYLIVIPPIKISTKLIFNKFILNKKSYLKSCNQYLKKPLKNDFEPMIRKNFIIIDNLINYLSKFSNFRLTGTGSCIFSEFDSECKAKEILYKLPNKIKGFVSKGTNISYLKEILKIRSNFNVLS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: DOHH_PLAVS
Sequence: MTGSTHNGGSRLIQYEDSSNKEFIRKYLVETRNEFIEKQMRALYECREIYKDDIDEVINILTYALENNDSVLLRHEVAYVIGQISNEKCNDILIKLLNDTEENLMVRHEAAEGLAAIGSDSNIEVIKKFLNDEKVEVRETCELALSSLLEKNKYAVCSCSNKDSIKEAIKKKRNDEFVSKKFNTIDPVVFTSSGNAKSVDALIEDLNNEAVPLKLRYEALFKLRDMETDVSINALGEVLIKDKKSAIFRHEVAFVLGQALHLNSLKYLISSLQNVGEHEMVRHEVALALGSLGSLNINSQEYKNVQSEIISTLKTFSKDACRVVAESCLVGLDYIAENLNMAIEVN
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A.  This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine.  Hypusination is unique to mature eIF-5A factor and is essential for its function.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
Protein: QUEE_GLOVI
Sequence: MNAASTVVKPVSAQSIPVQETFGPTIQGEGYWAGAVVDFIRLYGCPVGCPWCDTGYADGGPQLPRAVRTFSDLILELKSPRVVISGGEPFIHAALPALVEAIGRTGRAVAIETSGAFWQPVPDWAWVTLSPKEHVSPRHPVNPQMWRRANEVKIVIAGGAELDVYRRFLPPGVPVSLQPEWEARERTLPLTLELLKAHPRYRLSVQLHKYLQVP
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: DF236_ARATH
Sequence: MKNATSLIIYCFLMFLLMNNVKGQGKKKPPCPLGLSANGKCGHDGPKLCFSEMERKFNKDVVKTITHCKCWDDRRNNVDKHRCTCYLKHGFPCTNG
What are the official names of this protein?
Putative defensin-like protein 236, Putative S locus cysteine-rich-like protein 20, Protein SCRL20, SCR-like protein 20.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: AIM24_YEAS7
Sequence: MISPRVNTRVWQRSISLLSPQAAKTESNVVTKERTYIENLSKDIATSRFRLVDENGKIASITVQPDIPICIKKDCLVSIHNLNHLSLSYKWLNFWSNLIKFRSFKSSLFHRIIGSSVLEILAAPNFQISRRPFDSSRSLSVLNLTGTKDWNVFGKDSIIAFEQNSSLEIKSPIFPSARSLVSNSSKSQLPRKFQILNGRGNVLVCGGGLVYSIELIDECDKILVNSRNILAINGQSQLDIANSVERQELHVEGAYVGDSSNDTVAPKFIKNQTLKSAYGHTVQFFKRMRSWIRNQYEKRYIYGVDSYFMKIKGPRTILIQTHEMTTSKDNILTKLTSKSHVKKSTVNDNGVNLEKQVANDVNSKIIELANRPSLFIATVSQDGRVDFQSTSKFT
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPFD_MYCGI
Sequence: MSTFIGQLIGFAVIVFIIMKWVAPLVKSMMQKQQEAIRAALEESAEASKKLAEADAMHTKAVEDAKSEGQKVTDEARQDSERITAQLAEQADTEAERIKSQGAQQVQLMRQQLIRQLRSGLGAESVEKAEEIVRNYVSDPAAQASTVDRFLEELNAMAPSPAVLEAGATLNLRAASREALAELVKKFESVADGADSDTLTTVADELSGVAKVLLSETTLNKHLAEPTDDSTAKTRLVERLFDGKLGSNSLELLKTATAQRWSSEGNLIDALEHVARLALLARAERDGQSEEVEDQLFRFGRLLDSQSQLSRLLADTTVPTDKRVELLKKVVDSAGEVNGTVAALLTQTVELLRGEPADAAVSDLAELAVARRGEAVAEVTAAADLSEEQRTRLTEILSRIYGTPVSVQLDVDPDVLGGLLITVGDEVIDGSISSRLAAARTGLPD
What is the function of this protein?
This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta).  Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0) (By similarity).
What are the official names of this protein?
ATP synthase subunit b-delta.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: H1614_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLEQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELKAKLLEEDSEKSRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.14, HNTX-XVI.14, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.