PharMolix/UniProtQA huggingface dataset:
Protein: SUB4_ARTOC
Sequence: MVCLKTLSVFLAAFAAADARAVFKTQSSNKADIIPDSYIVVMKNGVSHDDFKAHVSSVSQIHSNNKAKRGTNTNGMQREFDIMNWRGYHGHFDPDTLDEILNDSKVDYVEHDQIVRISGLVTQRSAPSWGLGRVSHRQAGIRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDNADRHGHGTHTASTFAGTTYGIAKNANIVAVKVLGSDGSGSTSGIIAGINFCVQDAQSRGILGKAAMNLSLGGGFSQANNDAVTRAQNAGIFVAVAAGNDNKDARNYSPASAPAVCTVASSTVNDSKSSFSNYGSIVDIYAPGSDIIAARPGGGSTTMSGTSMASPHVAGMGAYMIGMGIDPRQVCDRLKQISLPAIRSPGPSTTNRLLYNGSGQ
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PETD_LACSA
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KLRBA_MOUSE
Sequence: MDTARVYFGLKPPRTPGAWHESPPSLPPDACRCPRSHRLALKLSCAGLILLVVTLIGMSVLVRVLIQKPSIEKCYVLIQENLNKTTDCSAKLECPQDWLSHRDKCFHVSHVSNTWEEGLVDCDGKGATLMLIQDQEELRFLLDSIKEKYNSFWIGLRYTLPDMNWKWINGSTLNSDVLKITDDTENDSCAAISGDKVTFESCNSDNRWICQKELYHETLSNYVGYGH
What is the function of this protein?
Plays a stimulatory role on natural killer (NK) cell cytotoxicity.
What are the official names of this protein?
Killer cell lectin-like receptor subfamily B member 1A, NKR-P1A, CD161 antigen-like family member A, Lymphocyte antigen 55A, Ly-55A, NKR-P1.7, Natural killer cell surface protein P1-2, NKR-P1 2.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL9_CAUSK
Sequence: MKVILLERVEGTGVLGDVVTVKDGFARNFLLPRHKALRANSANLKSFEVQRAEIEARNVKNREAAGKSGEGLDGKQYVMIRQAGESGQLYGSVAGRDVADAIKAEGGKVDRSMIVLDKPIKTLGVHEVKVKLHAEVTVTVTLNIARSQDEADRQARGENVVAAQFEEDRAAEAEAASDMAAGGAGSFEGDHYES
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GLPK_THEGJ
Sequence: MERYVLSLDEGTTSARAIIFDRESNIIGLGQYEFPQHYPKPGWVEHNPEEIWDAQFRAIKTALERAKVEPSQIAAIGVTNQRETTIVFDRDGKPLYNAIVWQCRRTAEMVEEIKREYGDMIKGKTGLVPDAYFSASKLKWLLDNVPGLREKAEKGEVLFGTVDTFLIYRLTGEHVTDYSNASRTMLFNIKRLDWDDELLEIFGIPEGILPEVRESSEVYGYTKKELLGAEIPVSGDAGDQQAALFGQAGFETGMVKATYGTGSFILANTGKTVRYSDNLLTTIAWGLNGKVTYALEGSIFVTGAAVQWLRDGIKIIKKASETEELATKLESNEGVYFVPAFVGLGAPYWDQFARGLIIGITRGTGREHLARATLEAIAYLTRDVIEEMEKLVGIKELRVDGGATANDFLMQFQADILNRRVVRPVVKETTALGAAYLAGLAVDYWESLEEIESLWKVEKVFEPGMDEETRRKLYHGWKEAVKRAMGWAKVVGI
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: ARLY_CHLAD
Sequence: MEHRLWGGRFSEPTAAEMRRFNDSFRFDRRLADVDITGSIAWAGALAQAGLIDEDEYAALVRGLELVRAEFANGTFVPAEGDEDIHTAVERRLRELIGDAALKLHTGRSRNDQVATDMRLYTIGIARQLDRRLRDLQLALLTQAELHTDTLMPGYTHLQRAQPITFGHWCLAYIEMFARDRSRLRDAITRMRVLPLGAGALAGNALGIERERLTELLDEFDELAANSLDAVSDRDFVAEILFICALIGIHLSRLAEDIILYASAEFGFIELADAYSTGSSLMPQKKNPDSMELLRGKSGRLLGNVVTLLTVLKGLPLTYNKDMQEDKEPLFDSFDTLDLGLQVAAAALATMTVHPERMAAALDDAMLATDLADELVRRGIPFRVAHGKVGQLVRRAQTLGVSLRHLPLTEYQAVEPSLDAGVYAIFDMARSVAQKASYGGTAPQRVREQCRRWRTILVESEA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_CROS8
Sequence: MSAIAPGMILLAYLCGSISSAILVCRIAGLPDPRDSGSGNPGATNVLRIGGKGAALAVLIFDVLKGMLPVWGAYALGVTPFWLGLIAIAACLGHIWPIFFHFRGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALVAPFYVWWFKPQFTFPVAMLSCLILLRHHDNIQRLWRGQESKIWSRFRKKRPQKKE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YL234_MIMIV
Sequence: MDSINPQSEFNSEEFVGRFNVIGRDRINCEYLSQLLYSAIIQNLKIKLDDKEYLIFNEYQENVFQLIDSLREFDENIIFIVLEYLASKEYHYLIDCIIMWWCLPNKNMFMSKNMYNKSYKQNIEKFNSKLTNRITHSLIESFCRDALSKTNKIPIHCLDLLWYYMNGMAIDLDFYNSNNCVNVTIIVPEDEESADNSDSTSYVTFGINMEFVLEMGIGKISYSTDPGKKKSFGNYLWQFITSEDTIDAIKFSKSFSNYKSQVLSINKNTVKYFGLDLKIPESVISRLM
What are the official names of this protein?
Uncharacterized protein L234.
Protein: YJU2B_DANRE
Sequence: MGERKGVNKWYPPDFDPAKHGSINGYYKTHPLRERARKLSQGILIIRFEMPYNIWCDGCKNHIGMGVRYNAEKKKVGNYYTTPIYRFRMKCHLCVNYIEMQTDPATCDYVIVSGAQRKEERWDMAENEQILTTERNEKEKLETDAMYKLDHGGKDKEKLRAAIPSLNELQEHQSGWKDDFQLNSALRRKFRTEKKVIAEEEEKDNAVRLRTGLSIPLVPEREEDKKLASLLTFQSPDSYEDKKQWKRQEISSRSWFNSPSSAAGGAAGSLLQKLGQQGRGAAVAKALSSSTSTLPILVRRKSESSKSETNNTMSTILPVDTHPAAKDTDATDLPSIVNNINVSINTDINSCTTDACKASSSSEEENSIDSCATGKSLVADYSDSDSGSEV
What is the function of this protein?
May be involved in mRNA splicing.
What are the official names of this protein?
Probable splicing factor YJU2B, Coiled-coil domain-containing protein 130.
What is the protein family that this protein belongs to?
Belongs to the CWC16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSA_CLOPS
Sequence: MDRNKEIFEESKKYMPGGVNSPVRSFGSVGINPPVIKSGKGAMIKDENGNEYIDFVLAWGPMILGHCDEDVVEAIKKTSEESIAFGASTKLELDLAKILCETLDNVDMIRMVNSGTEATMSAVKLARGYTKKDKIIKFAGCYHGHFDGFLIEAGSGVLTEGIPGCLGVPEESIKNTLIGIYNDEKQVEELFEKYGNDIAGIIIEPVAGNMGVVKCDPKFMRKLRELCDKYEALLIFDEVMCGFRVAYKGAQTLFDVKPDLVTYAKIMGGGLPCGAYGGRREIMENLSPLGGVYQAGTMSGNPIVMSAGLATVKKLYENPSYYDHIEKIGSKLEKGIIEIAKKKGLGLVVNRQGGMMTLFFTDLKEVKCYDDVKTCDGERFKRYFLHMLNKGFNIPPSQFEAMFLSVKHTEEHIDKFLEAFESFEG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_NEIMB
Sequence: MNTLQRRKTHQVRIDHITVGSEAPVVIQSMTNTDTADAKATALQIKELSDAGSEMVRITVNSPEAASKVAEIRRRLDDMGYATPLIGDFHFNGERLLAEFPECGKALSKYRINPGNVGKGVKGDEKFAFMIRTAAENDKAVRIGVNWGSLDQSLAKRMMDANLASSAPKPPEEVTKEALIVSALESAEKAVLLGLPEDKIILSCKVSAVQDLIQVYRELGSRCAYPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGSPRTQEVVVGQEILQTMGLRSFTPMVTACPGCGRTTSTVFQELAQDVQNYLRQKMSIWRTLYPGVESLNVAVMGCVVNGPGESKLADIGISLPGTGETPVAPVYVDGERKVTLKGDNIATEFLAIVEEYVKTNYGENGLKRHQGKVIPIHSL
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RECR_PROMM
Sequence: MIDQFERLPGIGPRTAQRLALHLLRQPEDQIRAFADALLAARSQVGQCQTCFHLSAEPLCDICRDGKRCDQLLCVVADSRDLLALERTREYKGRYHVLGGLISPMDGIGPDMLQIPSLIQRVDRDGISEVILALTPSVEGDTTSLYLARLLKPFTQVSRIAYGLPVGSELEYADEVTLTRALEGRRAMQ
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MCE1_CANGA
Sequence: MDARISPEIPGIIQPGNVTQDLKMLVCKLLNSPKPSKTFPGSQPVSFQHSDIRDKLVAQDYYVCEKTDGLRVLMLVVVNPITGEQGCFMIDRENNYYLVNGFHFPRLPQKKKEELLETSQNGTLIDGELVIQKNPMTKLQELRYLMFDCLAINGRSLVQSPTSSRLAHLGKEFYKPYYDLRSIYPDKCATFPFKLSMKHMDFSYSLVKVANSLDKLPHLSDGLIFTPVRTPYAVGGKDSLLLKWKPEQENSVDFKLILEIPMTEDNSVAKKDPRRWYYNYDAKPTFALYVWQGGSDVNTKLQNFEQPFDKREMQVLEKTYKRFAELSISDEQWQELKNLEEPLNGRIVECTKDPETGSWTMLRFRDDKLNGNHTSVVQKVLESISDSVTIDDLAESVPEIKSAWDERKNGAYQHHSSSFSESRQQPKAEPVAEKKQTEPKYVDDDDWSD
What is the function of this protein?
Second step of mRNA capping.  Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.
What are the official names of this protein?
mRNA-capping enzyme subunit alpha, GTP--RNA guanylyltransferase, GTase, mRNA guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic GTase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOBA_CERS4
Sequence: MRLFGLILAGGEGRRMGGTDKASLTLGGRLLVTWVAERLGPQVEELAISANGDPARFAGLGLPVLRDEHPQGPLSGVLAGLRWAAAAGADALVTAPVDTPFVPGDLAPRLWLAGEGTCAVAEAGGRVHPACGLWPVAVAEDLAAWLAAGEARVMGFAARHGAARAGFPDENAFLNLNAPEDLARAESLLRKDA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_NEIMA
Sequence: MENVNRIVAEGIAAVEAAQDFNALEQIKARYLGKTGELTGLLKTLGQMSPEERKTIGAHINECKNRFQTAFNAKRDALNEAKLQARLAAEALDITLPGRAQEGGSLHPVTLTLQRVVELFHGMGFEVADGPEIEDDFHNFQALNIPANHPARAMQDTFYVENGDVLRTHTSPIQIRYMLDKKEPPVRIIAPGRVYRVDSDATHSPMFHQAEGLWVEEGVTFADLKAVFTDFIRRFFERDDLQVRFRPSFFPFTEPSAEIDIMGENGKWLEVGGCGMVHPNVLKNVNIDPEKYTGFAFGIGLDRFAMLRYNVNDLRLFFDNDLNFLKQFVK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG086_FOWPN
Sequence: MTLFLVIFFILFLLLCYFFSFKRTNKMEIGINPIKKIPWSDNEHIFVSSLFTNKDKYLTGPMRLTYRPDSKTAVLDFKGTNYTYYLDNFDDVRKLVPTLLLSK
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex protein OPG086, EFC protein OPG086, Protein FPV078, Protein G3 homolog.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG086 family.
Protein: DCR1B_HUMAN
Sequence: MNGVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYCSPITAHLLHRHLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANHCPGSVMFLFEGYFGTILYTGDFRYTPSMLKEPALTLGKQIHTLYLDNTNCNPALVLPSRQEAAHQIVQLIRKHPQHNIKIGLYSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLADVFTVEEKAGRIHAVDHMEICHSNMLRWNQTHPTIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPRISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADLEKQPSHHPLRIKKQLFPDLYSKEWNKAVPFCESQKRVTMLTAPLGFSVHLRSTDEEFISQKTREEIGLGSPLVPMGDDDGGPEATGNQSAWMGHGSPLSHSSKGTPLLATEFRGLALKYLLTPVNFFQAGYSSRRFDQQVEKYHKPC
What is the function of this protein?
5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase.  Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse.  Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways.  Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology.  Also involved in response to DNA damage: plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation.  In case of spindle stress, involved in prophase checkpoint.  Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin (PubMed:31434986).  Exhibits no activity towards other beta-lactam antibiotic classes including cephalosporins (cefotaxime) and carbapenems (imipenem) (PubMed:31434986).
What are the official names of this protein?
5' exonuclease Apollo, Beta-lactamase DCLRE1B, DNA cross-link repair 1B protein, SNM1 homolog B, SNMIB, hSNM1B.
What is the protein family that this protein belongs to?
Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
What are the subcellular locations of this protein?
Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome.
Protein: GMHBB_HELPJ
Sequence: MITTNKALFLDRDGIINIDRGYVSQKEDFEFQKGIFELLKHTKTLGYKLLLITNQSGINRGYYTLKDFEQLTEYLQESLLKELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQICLERSFMIGDKESDMLAGLNAKVKNNLLLTQNPLKTPHSWIQCKNLKEMIDWIK
What is the function of this protein?
Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the GmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_BUCAP
Sequence: MKKLTIIFAGTAYFSMRYLDALTKSEHKVIAVITQPDRPSGRGQKIIFSPVKILSIKRNIPIFQPSELKNEKIQREIFNLNADMMIVVSYGKLIPKEILTMFPKGCINVHTSLLPRWRGATPIQSAILFGDKETGISIIKMNEKMDAGTIINSVKCNILPNDTTETLTFKLIEIGIQVLLKTLYYINKNIVVEKEQNEKHATFSKKISKKDALLNWNTEAYLLERLIRAFNPWPVCYFIVNQIAIRVWQAKIIPTVMKSACVGEIVAFNKNGIQINTAHQILNLQKIQFPGKKIINVEKIISSKKHWFHIGKII
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MEGG1_CAEEL
Sequence: MDNRGHFSSNGNFPPQGYHRREQSQEGMRIGNHHGPFSSGNMRSIGGSAQNQQQRHWTNMLNGSNNVENSWVCFSGNTSLADDPNVLSNFSALAQQRVNHFDTIVQERDNRNASFLNGSAVGNNLNTSFSVFGNLRGGDQDHRVLSDHTGIYTGLGSTGQNAVGTGIRLAADVANGNFLEQRAPTAMGHNQSYSALNQSLAPTLLDQYNQALLDQYNQSSQMAQGRGYPAPNIAYGLQNAGFPAPQIAHRPNTQNADPQAMNMNNRLRDHTFQMPHTNAQVPMSSLPGLFNLSMNHGSGNQQFQMNQSSSGPAPQLPNLSESFQMAQGSSQVTMSSRPAHSNTSMNHSSRNQYNHVDQRPSRPAPHLPTLTKEEEAFLETPDFEQFGRQLYNYLLPGILPNGAADTFSDAPKHQLLKLAKTLKPMLYDYWRKTMQMQNRGANINIIQWIIDFNAKFAALNSSVAKASNSSDVLNQTLPTAAEVSDVAREDASTSQPSKSRSMYIRPAASLDNTLETLDENLDSSQSHAGPVPAASTKPKTPSFEKMIRYSGIKKRSTMDMDNFVRMLDEKINFSPEPSTSSDIASSVKGYMSQSFLHQQDDEAPDCTKNVHSESDLKQAEPQESDKQSDKELPSNE
What is the function of this protein?
P granule component, which acts redundantly with P granule component meg-2 to promote P granule segregation during embryogenesis, and germ cell proliferation and differentiation in larval stages (PubMed:18202375, PubMed:21305687, PubMed:25535836).  In its phosphorylated form, and together with meg-2, promotes the disassembly of zygotic P granules in the anterior cytoplasm of pre-gastrulation embryos (PubMed:25535836).  In its dephosphorylated form, and together with meg-2, promotes the assembly and accumulation of zygotic P granules in the posterior cytoplasm of pre-gastrulation embryos (PubMed:25535836).  May function with the nanos family members nos-2 and nos-3 to promote germ cell proliferation during larval development (PubMed:21305687).  Required for fertility (PubMed:18202375, PubMed:21305687).
What are the official names of this protein?
Protein meg-1, Maternal effect germ cell defective 1.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Localizes to P granules in embryogenesis (PubMed:18202375). Localization to P granules may depend on mes-1 (PubMed:18202375).
Protein: F185A_MOUSE
Sequence: MFGRLPPCASRVRAGALVGALGARTCGSSGAQRQGSAPDDSGAGLARGALREWTLQVSPFGRLRARLPCHLAVRPLDPLAHPDGDRVQVAVCGVEHVARGLDSLQVKYDADRQEMAILSDDIDPQASVEVNAPVKFDLSIESSGSGSVKVQNIECDSCKIDTEQGTSILQSVKSQKLHVQTKGGDVICCGTVYGNIDIHASDKSTVSIEKLQGSCVNISTEDGLLQAKYLYTESSFLSSAAGNIALGNVHGNIILQSKMGNITVDSSCGCLKASSHQGAIDVYVSQLGEVALTTEEGSIAVKAPSSLRAYFKLSGKEVVVDEEAHVQEMAKDCKGDGVTVTGLMNQASKHERWINAIAPKGTVSFQHQSWFQSLKLPD
What are the official names of this protein?
Protein FAM185A.
Protein: RPOC_VIBC1
Sequence: MKDLLNFLKAQHKTEEFDAIKIGLSSPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFEMYVVTEPGMTDLEKSQMLTEEEYLDRLEEWGDEFTAKMGAEAIKDLLGSMDMHAEAEQMREELETTNSETKRKKVTKRLKLVEAFIQSGNNPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLETRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDKINVKGEGMYLSGPAEAEKAYRTKQAELHARVKVRITETVVDEDGNSTTETKMVDTTIGRAMLWQIVPAGLPYSIVNQKLGKKQISNLLNEAYRKLGLKDTVIFADQIMYTGFAYAALSGVSVGIDDMVVPPAKYTEIAEAEEEVREIQEQYQSGLVTAGERYNKVIDIWASTNDRVAKAMMANLSSETVVNRDGEEEQQESFNSIYMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFKEGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVVTEHDCGTHEGVDMMPHIEGGDVKVALTELALGRVVAEDVLKPGTEDVLIPRNTLIDEKWCQIMEENSVDSMKVRSVVTCDSDFGCCAQCYGRDLARGHLVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAAENSIQAKTTGTVKLHNAKFVVNKDKKLVITSRASELTIIDEFGRTKEKHKLPYGSMLSKGDNDAVTAGEVVANWEAHTMPIITEVAGRIQFVDMIDGVTVSRQTDDLTGLSSSEVTDPAARPAAGKDMRPAIKLVDEQGNDVMIPGTEMPAHYFLPGKAIVNIEDGAEVGIGDTLSRIPQKSGGNKDITGGLPRVADLFEARKPKEPAILAEHTGTVSFGKETKGKRRLVITRDSGVTYEEMIPKHRQLNVFEGERVERGDVIADGPESPHDILRLRGVHAVTQYIANEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHAGDSEFLPGEQVEYSQVKIANRNLEAEGKEPARFERELLGITKASLATESFISAASFQETTRVLTEAAVSGKRDDLRGLKENVIVGRLIPAGTGFAYHQDRQAKRAEAQEGPSAEQATDNLAALLNAGFSSDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: DAPE_ECO5E
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMDFADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKAVEALMARNERLDYCLVGEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CHS3_GERHY
Sequence: MATSPAVIDVETIRKAQRAEGPATILAIGTATPANCVYQADYPDYYFRVTESEHMVDLKEKFQRMCDKSMIRKRYMHITEEFLKENPSMCKFMAPSLDARQDLVVVEVPKLGKEAATKAIKEWGFPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNEGHLDSLVGQALFGDGAAAVIIGSDPDLSVERPLFEMVSAAQTILPDSEGAIDGHLKEVGLTFHLLKDVPALIAKNIEKALIQAFSPLNINDWNSIFWIAHPGGPAILDQVEFKLGLREEKLRASRHVLSEYGNMSSACVLFILDEMRKKSIKDGKTTTGEGLEWGVLFGFGPGLTVETVVLHSLPATISVATQN
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 3, Naringenin-chalcone synthase 3.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: PUR9_GEOSM
Sequence: MAKIGRALISVSEKTGVVEFSRALAGYGVEILSTGGTAKLLREAGIAVKDVSEFTGFPEMLDGRVKTLHPKVHGGILGMRENPAHVAKMQEHGIEPIDMVVVNLYPFEATVAKEDCTMEDAIENIDIGGPTMLRSAAKNNRDVTVVVDHADYAVVLDEMKNSGGSVSCETNFRLAVKVYQHTAAYDGAISNWLGARTGDGVAAFPDTLTLQYKLAQGMRYGENPHQSGAFYVEKGSKEASISTARQIQGKELSYNNIGDTDAALECVKQFTEPACVIVKHANPCGVALGANIMEAYDKAYKTDPESSFGGIIAFNRELDESTARAIVERQFVEVIIAPKVTEAASEVVAAKKNVRLMECGFWPENPAPRFDYKRVNGGMLVQDADLELFTELKVVTKRAPTDKEMEDLLFTWRVAKFVKSNAIVYGRDNSTVGVGAGQMSRVNSARIAAIKAEHAGIPVQGAVMASDAFFPFRDGLDNAAAVGVTAVIQPGGSMRDAEVIAAADEHGIAMVFTAMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: STIM_DROME
Sequence: MRKNTIWNYSLIFFCCVLKSISTLDHGPHTVSVDSNRHNTQHQYKQNPNVASQRHSSHESGQSLHNSQSEHVTHIAASHAGSGGEHSTHLAQNLHRSSYNLLSEAMSQAVSNEFSSMGSGSADGACAADDFDCYSGSVQDRFGMEAIASLHRQLDDDDNGNIDLSESDDFLREELKYDSGYEKRQKAFHFNDDMHISVKELWEAWLRSEVHNWTIEQTTDWLAQSVQLPQYVDLFKLHKVTGAALPRLAVNNLQYVGNVLGIKDPIHKQKISLKAMDVVLFGPPRETGTRWKDYILVTLLLSAIIGCWYAYQQNKNAKRHLRRMAQDMEGLQRAEQSLQEMQKELERARMEQENVATEKLDLERRLKEAPTLSSSNSDLEVQQLKKEIEMLRNELSRAEFELVDNCWSPPPQLQSWLQYTYELESKNHQKKRTSAEKQLQSAREACEKLRKKRSSLVGAFVSTHGKSIDDVDRSIVEARNALGDVTNELQERLHRWKQIETCLGLNIVNNNGLPYLENVLYGRNGGLQSSMGMSSTKGSRARITNSTEDLDDESIQGKLNFENFSLLATE
What is the function of this protein?
Plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores.
What are the official names of this protein?
Stromal interaction molecule homolog.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.