PharMolix/UniProtQA huggingface dataset:
Protein: LIPLA_PLAF7
Sequence: MKRIFRLVRRCHYSTEKRTNGPLVLVSNNQNIHFNLSLENFLLNNYNDLLKYLNINTIEKFNEPILFLWRNNRSIIIGKNQNIWSECNLKNIKEDGVLVARRFTGGGAVYHDLGNVCFTFLNNNINTSSNFLIILNTLKNHFNIEAKTQGRNDITVNDQKCSGSAFKKIKDVFLHHGTILINLEKNILNKYLTPDKIKYIKHGVSSVNARTINLSEINNNITCENLCIALIKEFTKFYEQNYKENINNIKNLENNINNSNFQNKEQININNTNENNLINNTNIIPNDITVHYIDQNNNITKNPEFLKYYNLLKDWDWCYGKTPKFQNHIWKQFTFGKLELFFNVSNGFIKDGNIFSDCLDINLIDHLKSIFNNDIKYSKEDISIFFKKLNVENKNYLDEVRSWILQEL
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (PubMed:17244193, PubMed:25116855, PubMed:28543853).  In the mitochondrion, functions as a redox switch between two lipoylation routes (PubMed:25116855).  Senses the oxidation state of lipoate and determines which downstream enzymes will be lipoylated (PubMed:25116855).  In low reducing conditions, uses lipoate in its oxidized ring form to lipoylate glycine cleavage system H-protein GCVH (PubMed:17244193, PubMed:25116855, PubMed:28543853).  In high reducing conditions and together with LipL2, uses reduced lipoate (dihydrolipoate) to lipoylate the E2 component of the branched chain alpha-ketoacid dehydrogenase complex BCKDH-E2/BCDH and the E2 component of the alpha-ketoglutarate dehydrogenase complex KDH.  LipL1 is responsible for catalysing the activation of lipoate, forming lipoyl-AMP while LipL2 is required but is not capable of catalyzing this reaction (PubMed:17244193, PubMed:25116855).
What are the official names of this protein?
Lipoate--protein ligase 1.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
Protein: HUTH_ROSDO
Sequence: MTLTLTPGAATLAQLQDIWANNRAVTLCPSAHAGIKAAQALVAKAAAGDDAVYGVNTGFGKLASVKIAAKDVATLQRNLILSHCCGVGEPLDAATTRLMMVLKLLSLGRGASGVAMTTLEIIENMLARGVTPVIPSQGSVGASGDLAPLAHMAAAMIGEGEAVFEGTRMAAGDALRRAGITPIVLGAKEGLALINGTQFSTACALVGLWGAWRNAATCVLTCALSTDAIMGSTAPLQDAIHTLRGHAGQIAVARAQRALMAGSQIRESHVEGDTRVQDPYCIRCQPQVTGAAMDILHFAGRTLEIEANAVTDNPLVLVEDELIVSGGNFHAEPVGFAADQIAVAVSELGAIAQRRVALMVDPTLSFDLPPFLTPDPGLNSGLMIAEVTTAALMSENKHLANPCTTDSTPTSANQEDHVSMAAHAARRLLRMNANLNVILGVEAMCGAQGIEFRAPLETSAPLKAAMAVLRAHVPTIAEDRYMAPSIEAASALVANGTLAACVDLPAFVKGEAA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_UREU1
Sequence: MKIVDLLAYQVLDSRGQPTVAVKLFLENDQSVVAMVPSGASTGTKEALELRDGDANYFFSKSVKLAIQNVNNIIRPHLLNKNVLNFFELDNLLINLDGTENKTKLGANALLGVSIVIVKGGAVAASKPLYQYIKEDLMHNYDEHYYAPIPLMNFINGGAHADNNLDIQEFMIVPLNAISFSQAIQTGSEIFHELAKILKANHLNTAKGDEGGFAPMLNDNYAALELLVRAIKKAHYFPSKKQGVCLALDVASSELYENEKYVFKKALSHNTNLEQTSFSSDEWAKYWSDLASQFPIISIEDCFDENDWNGFSLFLKNNPHIQSVGDDLYCTNLKYLQKGINFKATNAILIKPNQIGTISETLDVIKYAQENNINTIISHRSGETEDTFIADFAIGVGAGQIKTGSLSRSERIAKYNRILEIEQELKDKLVYEPNKFFKFN
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RBSD_ECOL6
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAVIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1344_MYCVP
Sequence: MARTADDSWDPASSVGATATMVAAGRAAASADPDPLINDPYAEPLVRAVGLSFFTKMLDGELDLSQFADGSPERVQAMIDGMAVRTRFFDDCCGTSTTAGITQVVILASGLDARAYRLGWPAGTVVYELDQPAVIEFKTRTLAGLGAHPTATHRPVPIDLREDWPAALHAAGFDASRPTAWLAEGLLIYLPPEAQDQLFDRITALSAPGSTIATEYAPGIIDFDDEKARAMSAPMREMGLDIDMPSLVYAGTRSHVMDYLAGQGWEVTGVPRRELFTRYGRPLPPEAGDTDPLGEIVYVSAHRPQ
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mvan_1344.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: RLME_SALPB
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A_ACIGU
Sequence: MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLILELAGNAARDNKKTRIIPRHLQL
What is the function of this protein?
Acipensins are antimicrobial peptides.  Acipensins 1 and 2 have antibacterial activity against Gram-positive bacteria L. monocytogenes EGD (MIC are 1. 1 uM and 1. 0 uM, respectively) and S. aureus ATCC 33591 (MIC are 0. 9 uM and 0. 6 uM, respectively), against Gram-negative bacterium E. coli ML-35p (MIC are 0. 7 uM and 0. 3 uM, respectively) and antifungal activity against C. albicans 820 (MIC are 1. 0 uM and 0. 9 uM, respectively).  Acipensin 6 has antibacterial activity against Gram-negative bacterium E. coli ML-35p (MIC=2. 5 uM).  Antimicrobial activity is reduced by high ionic strength.  Acipensins 1, 2 and 6 have no hemolytic (up to 40 uM) or cytotoxic (up to 20 uM) effects on human cells in vitro.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
[Histone H2A]: Nucleus. Chromosome.
Protein: CHLB_PROMM
Sequence: MELTLWTYEGPPHVGAMRIASSMEGVHYVLHAPQGDTYADLLFTMIERRGRRPPVTYTTFQARDLGGDTAELVKGHLHEAVERFNPEALLVGESCTAELIQDQPGSLASGMGFNMPVVGIELPAYSKKENWGASETFYQLVRGILSKQPSEQSGVSHSPAAWKSQGRRPRVNLLGPTLLGFRCRDDILELEKLLNQHGIDVHVVAPLEARPADLMRLPNADLNVCLYPEIAEATCLWLERNYGMPFSKTVPIGVGATKDFLEELHQLLEMPAPNPGEGAEQSRLPWYSQSVDSNYLTGKRVFIFGDGTHALAAARIADQELGFKVVGLGTYSREMARPVRAAAKELGLEALISDDYLAVEAAMAEAAPELVLGTQMERHSAKRLGIPCAVISTPMHVQDVPARYSPQMGWEGANVIFDSWVHPLMMGLEEHLIGMFRHDFEFVDGHQSHLGHLGGHQSQTEQQQSQAATNPSTQSNADSSSEESPLWTPEGEAELAKIPFFVRGKVRRNTEKYARQAGCRCIDSETVYDAKVHFRA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: NUOH2_GEOMG
Sequence: MGYEILGLPMAYYIAMVLKVLVVFVFVLLTVAYATYAERKIIGHMQVRLGPMRTGWHGLLQPIADGVKLFFKEEIIPSKADKFAFLIAPLIALVPAFIGFAVIPFGETIEVGGYKIPLQIAAYYDTASGQVVDLNVGVLYILALASIGVYGIVLAGWSSNSKYSLLGGLRSSAQMISYELAAGLAIISVFMLSESLSLQKIVADQANGAWYAFKQPLAFILFFICSIAEINRTPFDLPEAETELVSGFCTEYSSMKYAMFFMAEYANMVTVCAVTTTLFLGGWHGPSFLPGWFWFIAKVYFLIFTCMWIRATYPRYRYDQLMRLGWKVFLPLTLINIVVTGIIVSL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 2, NADH dehydrogenase I subunit H 2, NDH-1 subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEF_RICCN
Sequence: MPLSTSLLGKKSTYKDSYDVTLLFKIPRINNRNELGINSNNLPFYGVDVWNTYELSCLNKNGKPWVGVGTFYIPTDSENIVESKSFKLYLNSFNNFVVESVKELERIILQDLSNVTHAKVTGRIFPINTKVEFGVPSGKNIDDLDIVCNNYGAPDNSLIEYEDVLVEEEINSHLLKSNCLVTGQPDWGTIVIKYKGKKLKYDSFLKYLISFRNCNEFAEQCAERIFTDIKNAISPDFLSIYIVYARRGGIDICPYRSTDKSYTLPSDKRFIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_STAAR
Sequence: MAAIKPITTYKGKIVPLFNDNIDTDQIIPKVHLKRISKSGFGPFAFDEWRYLPDGSDNPDFNPNKPQYKGASILITGDNFGCGSSREHAAWALKDYGFHIIIAGSFSDIFYMNCTKNAMLPIVLEKNAREHLAKYVEIEVDLPNQTVSSPDKSFHFEIDETWKNKLVNGLDDIAITLQYESLIEKYEKSL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: IF2_EHRCR
Sequence: MNESKSVVDSGLMSGKIERTTLKLSDKLKLSSNIHQGTKFSLKKSVTTVEVRKSKKRKDINNIEQASVVLQNDNAYQDNESNNSLTIQEQISRMNALQNANICEKKEDIKEDTSDVNLQVTESTSVEKSESDDVTLEEESSKKVEEQVVEEAHDNTDTVSLNVVENVQEESQVDNQVESSNISDILQPKGIEEKKLKKYEKEHEEKKGNPKKGVSNNMYSKHVKLVIEEELEDNNKQVIQTHKSRKNRSTSSVKNKITRKVLIPKKITVQELASSMSERVKDVQHMLFQMGRRDIKPTDFLDSDHASVIVEAFNHTFKLVNDGKLEEDLYADGNDKELLPRAPVVTVMGHVDHGKTSLLDAIRKSNVADGEFKGITQHIGAYQIMLDGDKRITFIDTPGHEAFTAMRACGTNVTDIVVLVVAADDGIMPQTIESINHVKAANVAMIVAVNKIDKHDANIDKITNSLLNHGVVAESLGGDVIVVPVSAKERINLDQLKSSILLMAELLELKAVYDTRASGVVIESKVDRNCGVVATLIVQKGTLKAGDIIVVGHNSYGKVRNMFNSDGRSEKVAIPSMPVKVLGLNNVPNSGTNFIVVDSEKQARELISYRQELFNAELEANAKPKMDANSILACGVVDELNVILKCDVMGSVEAICYSISKITHEDIKLNVLYKGVGNVTKSDVLLAETSNSIILAFNVKTDASVKELAKQKCIEIKHYSVIYDIIDDVKKILSSMLKPLQQEVQVGTLSIRKVFSSGSIGSVLGCYVTNGIVRKGALVKLIRNNNVIHEGKIKVLRRFKDDVKEVAAGFECGILLDYSKEIYPESDIIHILEIVEEIRVIK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI11E_ORYSI
Sequence: MAAEAAATSRFAAACGALSQYVRAADNVHRARTAAAAAAVRPLPLMPGADVAGDEREEEGGGAAASSAAAQMTIFYGGRVLVLDECPADRAAALLRLAASSRGVPRDDLASTAAAAGESADLPVARKASLQRFMEKRKGRLAARGQPYRRHDAAAAARGDHLALAL
What is the function of this protein?
Repressor of jasmonate responses.
What are the official names of this protein?
Protein TIFY 11e.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUNZ_DICD3
Sequence: MPLSYLDKNPVIDSKKHALRKKLFLSCAYFGLSLACLSSNAWASVEPLSVNGNKIYAGEKAKSFAGNSLFWSNNGWGGEKFYTADTVASLKKDWKSSIVRAAMGVQESGGYLQDPAGNKAKVERVVDAAIANDMYAIIGWHSHSAENNRSEAIRFFQEMARKYGNKPNVIYEIYNEPLQVSWSNTIKPYAEAVISAIRAIDPDNLIIVGTPSWSQNVDEASRDPINAKNIAYTLHFYAGTHGESLRNKARQALNNGIALFVTEWGTVNADGNGGVNQTETDAWVTFMRDNNISNANWALNDKNEGASTYYPDSKNLTESGKKVKSIIQSWPYKAGSAASATTDPSTDTTTDTTVDEPTTTDTPATADCANANVYPNWVSKDWAGGQPTHNEAGQSIVYKGNLYTANWYTASVPGSDSSWTQVGSCN
What is the function of this protein?
Represents 97% of the global cellulase activity.
What are the official names of this protein?
Endoglucanase Z, Cellulase Z, Endo-1,4-beta-glucanase Z, EGZ.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: UTP10_CANGA
Sequence: MSSLSDQLAQVAASNASVAFDRKKRQKLHSASLIYNPKTAATQDYETIFENALGALQELCDIEPRFQVFSKTLFSETSITIDRNVQSKEENKNLDNAINAYLLMVSSKWHLAPALHATEWLVRRFQIHVHNTEILLLSTLNYYQSPIFKRILNIVKLPALFQPLSNFVKNDSNPTNITIIKMFNDTDFLKLYSNYLSKCIKHKSTYTNQLLFVTCCFINLIAFNSSNDEKLEFLVPIILEIAAKLLASGSTDCQIAAHTILIVFTAALPLKKDIVVAAIETILANLKDKKAEQSAFWAVIKISQTLKGQQAIEHLPANIYKIFDKHYTWVRVLDLLTEEPSIKCDKFMTSYIRAMIRFDHSKLDMVVPLVQKLSLEKYEFRSIVIDLIHLSEVLEDKSKLIDLFEFLVKENESLVINCLSSLNLTGEMFEIRLTTSLFSKTNDDNELELLKTLNSHKNTSSDKKEETKPFKQFLEENSEFIVTSNKSMISEDDEKFNKILGLFIEAIGTGYQAGLFLSSFMTTLEARLTFLLRVIVSPSAPIALRLLAMNNISKYIQSIDKELNLFTLIPFLLVAQSGSSKNLKISVKKILGQIGNRPFTKHYFMSNQLYGEGKDIKVPSPSDSEMWTKNFIENYVVENVDISGVFIPKQAEKVFLLFWAQQVLDIPLPYPQYMILNFLGKYVPNTASYSGLFEESISSYLERREELLLRCALNKTDPIQFETAMVNLISNKEKHHFMLDFIINVLQSDYEDLIQILVDRLVEVFATFKTSNQLRIVQEILQSVTKEDQIYDALGTLQSLQIDPDTFVCIFKENSINSESDVTSFPKRRRRRSSTNKAALQSAEVSQIAEDHLKKLTIMLETLDKQKVKGSEELLSSLFFTLADFETLDQDGGLPVLYAEELLASAMLNTIRSLKDQGLTQLQNVRADIIVSAIRTSSSPQVQNKLLLVIGELATLSSEIVLHSVMPIFTFMGAHSVRQDDEFTTQVVEKTILTVVPAFLAANSENITEEIEFLVMSFATALQHIPKHRRLRLFTTLVQALGSDNSLGPLLLLISQQYSNAVKSFKISESRSLVEFTKLLLSKFEVQEQITGFRKFLELYEKLLLANKNPEKKVTLETQALFSSKILNLTQSEFCDLTNNSYDFLTKVIVDTNDDYYDSSRNFKIRLYSIILDPTVSNATRKALDESYSSVLKMILSLIADYPDIFVFETNENSEKQNSVHFIGDILEEIKQSLYGLLHAILDVLPINVFLTTTVPLLESSIDKEIRYHIASNIFDKFENETVDDHELTQSVVHTLNEKIPQEENNVAQVLLNLQSSLINKYGSFFDNNLLVEVLNLASGLISTGPRELQISSIAVITNCVSVMGVKFISFYPKVVPICIKLFNETRASKEELAPQLQLSILLLFTALVKSIPSFLTSDLISLMKLIFFSSGVEVTTRLSVIQLVTEKLDLKNVLGTLLKVWNSEVKESGDSTAISLFLSLLEGTVEKIEKKSATSQSPLFFKLLICLFEFRSQSEFDTNTISRIESSVYAVANTYVLKLNDKVFRPLFVILIKWAFDGEGVSSESITEKERLTAFFKFFNRLQENLKGIITSYFTYLIEPVNELLKRFISGDISDVNLRRLLLNSLTSSLKYDRDEYWQSTSRFELICPSLVNQLSNIEPTIGKYLVKAIGSLAAKNSSVDEHNQMMNKLLVEHMKATCSSNEKLWAVRTVKLIYSKVGESWLVLLPQMVPIIAELLEDDNEEVESEVRGGLVRVMENVLGEPFDRYLD
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Involved in ribosome biosynthesis (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 10.
What is the protein family that this protein belongs to?
Belongs to the HEATR1/UTP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Membrane; Multi-pass membrane protein.
Protein: MAK_MYCVP
Sequence: MTLAFGDWIVHRRWYAGRSRELVSAEPAVVTPLRDDLDHILLDVTYTDGTVERYQLVVRWADSPVAGFGEAATIGTALGPQGERIAYDALFDPDAARHLLRLVDASATVADLRFTREPGATLPLYAPPKVSSAEQSNTSVIFGKDAMLKVFRRVTPGINPDIELNRVLAQAGNRHVARLLGSFETSWAGPGTDRCALGMVTAFAANSAEGWDMATASAREMFADVVGSDFADESYRLGNAVASVHATLAEALGTSTEPFPVDTVLARLQSAARSAPELAGRAAAVEERYRRLDGRAITVQRVHGDLHLGQVLRTPDDWLLIDFEGEPGQPLDERRRPDSPLRDVAGVLRSFEYAAYQKLVELAPEQDADGRLADRARNWVDRNSAAFCAGYAAVAGDDPRRDGDVLAAYELDKAVYEAAYEARFRPSWLPIPMRSIDRILG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate.  Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity).
What are the official names of this protein?
Maltokinase, MaK, Maltose-1-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
Protein: NDK_SULAC
Sequence: MTLQRTFVMIKPDGVRRRLVGEIISRFEKRGFNILALKMVHMDRATAERLYQEHKGKGFFNELINYIISGPVVCMIIEGDDAVSVVRKMIGATDPKEASPGTIRGDYALSKSENVIHASDSEEKAKTEMGIFFQDVTEIGAQARM
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_THEAC
Sequence: MSSTMSADQSNRARPVIRIKENPEDFTVEEVADIPKSDNGKYTIIKAEIIDWDTNRIVEEIASALRISRKRISYAGTKDKRARKIQYFCINAPVDVSVLAFKGFRIIDRFRSDHYLRLGDLTANHFRIRFQGASDDYIEQRYEKMMECGGFPNYFGQQRFGSRRRNTHDVGRLIVTGRYEDAVRLYLYDERYDIEDYRREFIETLDYNRALEKFPRTLRFERSIIGYYAQHHTFKGAFDALPKNLSIMFVHAYQSYLFNRMLSLRIEKYGLNRAIPGDTAFPVDRYFNPDKSRPVEVNEVNVDTINQLIERDRLRVALPIIGSEVGPDQSDFGEIEKKILEEEHVDRSMFRNSEYPHLSSTGDRRIVSAKPVDFSVSNSVMDFTLGRGIYATTLISTFGDLVDFDAESDGF
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: VPS28_CAEBR
Sequence: MSQNSNLMREVRLFENHSEREQMENLSELFAVLNALEHLEKMFSRDHVTADEYKTECFKLIDQYKVTMRLVHGATSIEEFAKKYRLHCPAAIERIREGRPITVKDDQGNVLKHIASIVEQFITFLDSLRLNTRAVDDLYPVLDDLYNAINSTSRVPIDANVTTKVKKWHDRLSSMAATDEISDDEARQMIFDTEGAYQSFQKALNEQKH
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 28 homolog, ESCRT-I complex subunit VPS28.
What is the protein family that this protein belongs to?
Belongs to the VPS28 family.
What are the subcellular locations of this protein?
Endosome.
Protein: GON3_ONCMY
Sequence: VQVVVLALVAQVTLSQHWSYGWLPGGKRSVGELEATIKMMDTGGVVVLPEETSAHVSERLRPYDVILKKWMPHK
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Progonadoliberin-3, Progonadoliberin III.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS11_STAAN
Sequence: MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DTX22_ARATH
Sequence: MAGEGGELTAALLKKTTENGGEENDELGLKEKVWIESKKLWVVAAPSIFTKFSTYGVSLVTQGFVGHIGPTELAAYSITFTVLLRFSNGILLGMASALGTLCGQAYGAKQYHMLGIHLQRSWIVLTGCTICIMPIFIFSGPILLALGQEDHIVRVARVIALWLIAINFTFVPAFTCQIFLQSQSKNKIIAYVSAVTLGLHVFFSWLLVVHFNFGITGAMTSTLVAFWMPNIVQLLYVTSGGCKDTWRGFTMLAFKDLWPVFKLSLSSGGMVCLELWYNSILVLLTGNLKNAEVAIDALAICINVNALQMMIALGFLAAVSVRVSNELGRGNPEGAKFATIVAVFTSLSIGLVLFFVFLFLRGRISYIFTTSEAVAAEVADLSPLLAFSILLNSVQPVLSGVAVGAGWQGYVAYINLACYYLLGIPVGLVLGYVVGLQVKGVWIGMLFGIFVQTCVLTIMTLRTDWDQQVSTSLKNINRWVVPESRDANQISSEE
What are the official names of this protein?
Protein DETOXIFICATION 22, AtDTX22, Multidrug and toxic compound extrusion protein 22, MATE protein 22.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVB_XYLF2
Sequence: MDRIIDSAATREDEAIEVSIRPKRLADYLGQQPVREQMDIYIQATKARAEALDHVLIFGPPGLGKTTLSHVIAYELGVKLRVTSGPVIEKAGDLAALLTNLQPYDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGEGPAARSIKIDLPPFTLIGATTRTGLLTAPLRDRFGIVQRLEFYSPEDLARIVRRSAGILNIDCTTEGAAEIAQRARGTPRIANRLLRRVRDYAEVKADGQITIEVAQAAMQMLKVDQGGFDELDRRLLHTIVEYFDGGPVGIESLAASLSEERGTLEDVVEPYLIQQGFLVRTARGRMATDKAYQHLALQPRERVSAFTDPEDLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HMN12_HUMAN
Sequence: MAPRGFSCLLLSTSEIDLPVKRRA
What is the function of this protein?
Plays a role as a neuroprotective and antiapoptotic factor.
What are the official names of this protein?
Humanin-like 12, HN12, MT-RNR2-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the humanin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: FLGB_YEREN
Sequence: MLDKLDGALRFQQEALNLRAQRQEILSSNIANADTPGFQARDIDFSSQLKKVMEQGRASGTGVSLSLTSARHIPASTVQPPDLDLLFRVPDQPSMDGNTVDMDRERTNFADNSLKYQTDLTVLGGQIKGMMSVLQQG
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.