PharMolix/UniProtQA huggingface dataset:
Protein: VATE1_MOUSE
Sequence: MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKKDVDVQIDQEAYLPEEIAGGVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit E 1, V-ATPase subunit E 1, V-ATPase 31 kDa subunit, p31, Vacuolar proton pump subunit E 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
What are the subcellular locations of this protein?
Apical cell membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: MATRX_TUPVT
Sequence: MLRWFSFGSNEGSEVAGNGWSVKPIGNMSIKKDDPVGFPQGYQCLLKVIIQLEKKDPTKSDVSELIAGWVKRYSGPHLLERLIKALIILTVPKLSRENIDNHVKLGGLFEGQVTFHFSSRDLIPTKYLSYATSIRTTVKGIYSYLSIEAELNPSSHQGTSVAKLLRASDVAKYYDNTLQSIFSQFEIKNVTITDDQIIFN
What is the function of this protein?
Plays a major role in assembly and budding of virion, by recruiting cellular partners of the ESCRT complexes that play a key role in releasing the budding particle from the host membrane.  Condensates the ribonucleocapsid core during virus assembly.
What are the official names of this protein?
Matrix protein.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein. Host nucleus membrane; Peripheral membrane protein.
Protein: WNT2_COLGU
Sequence: MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSAKDSKGIFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANERFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRCQDCLEALDVHTCKAPKNADWTTPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: BI2L2_BOVIN
Sequence: MAPEMDQFYRSTMAIYKSILEQFNPALENLVYLGNNYLRAFHALSEAAEVYFNAIQKIGEQALQSSTSQILGEILVQMSDTQRHLNSDLEVVVQTFHGDLLQHMEKNTKLDMQFIKDSRQHYEMEYRHRAANLEKSMSQLWRMERKRDKNAREMKESVNRLHAQMQAFVSESQRAAELEEKRRYRFLAEKHLLLSNTFLQFFGRARGMLQNRVLLWKEQSEASRSPSRAHSPGLLGPVLGPPYPSGRLTPTRLDMPQRALGEFGSPRSRHGSGSYGPEPAEARSASQLEPDHRRSLPRTPSASSLYSSSTQRSRSNSFGERPGGGGGGGGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLEGSSSSGWFPEAYVKPLDELPVNPMNPLNPVTSMNPRSPVNELPSRLRSYPLRGSHSLDDLLDRPGNSTASSDYWDGQSRSRTPSHIPSRTPSPAPTPLPSSRRSSMGSMGVASDVKKLASWEQQPPELFPRGTNPFATVKLRPTVTNDRSAPLIR
What is the function of this protein?
Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures.  Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups.  There seems to be no clear preference for a specific phosphoinositide (By similarity).
What are the official names of this protein?
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2, BAI1-associated protein 2-like protein 2, Planar intestinal- and kidney-specific BAR domain protein, Pinkbar.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane. Note=Localizes to RAB13-positive vesicles and to the plasma membrane at intercellular contacts.
Protein: COXN_THUOB
Sequence: SNTSHQDFHLFYGDNGMPVH
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7B-heart, mitochondrial, Cytochrome c oxidase polypeptide VIIb-heart.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIb family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DEOB_STAAM
Sequence: MTRPFNRVHLIVMDSVGIGEAPDAADFKDEGSHTLRHTLEGFDQTLPNLEKLGLGNIDKLPVVNAVEQPEAYYTKLSEASVGKDTMTGHWEIMGLNIMQPFKVYPNGFPEELIQQIEEMTGRKVVANKPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQIAAHEDIIPLEELYDICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALKPFGKTVLDHLKDGGYDVIAIGKINDIYDGEGVTEAVRTKSNMDGMDQLMKIVKKDFTGISFLNLVDFDALYGHRRDKPGYAQAIKDFDDRLPELFSNLKEDDLVIITADHGNDPTAPGTDHTREYIPVIMYSPKFKGGHALESDTTFSSIGATIADNFNVTLPEFGKSYLKELK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP7_ORYSJ
Sequence: MEAGEEIEDGEPSTPTYKAHHPPPHLPPPMRSSGVSLVLSVADLVLRFVAIGGTAGSAIAMATTSETLPFAAPFVRFRAEYSDLPTLMFFVVASSVVCAYLVLSLPASVVHVVRPGARSSRAILAFLDTVMLALLTASASAAAAIVYLAHRGSARANWLGICQQFTSFCQRITASLVGSFAAAVVLVALVFLSALSLARRA
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 7, OsCASP7.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: T14H_TAXCU
Sequence: MDVFYPLKSTVAKFNECFPAILFIVLSAVAGIVLPLLLFLRSKRRSSVGLPPGKLGYPFIGESLLFLKALRSNTVEQFLDERVKNFGNVFKTSLIGHPTVVLCGPAGNRLILANEEKLVQMSWPKSSMKLMGEKSITAKRGEGHMIIRSALQGFFSPGALQKYIGQMSKTIENHINEKWKGNDQVSVVALVGDLVFDISACLFFNINEKHERERLFELLEIIAVGVLAVPVDLPGFAYHRALQARSKLNAILSGLIEKRKMDLSSGLATSNQDLLSVFLTFKDDRGNPCSDEEILDNFSGLLHGSYDTTVSAMACVFKLLSSNPECYEKVVQEQLGILSNKLEGDEITWKDVKSMKYTWQVVQETLRLYPSIFGSFRQAITDIHYNGYIIPKGWKLLWTPYTTHPKEMYFSEPEKFLPSRFDQEGKLVAPYTFLPFGGGQRSCPGWEFSKMEILLSVHHFVKTFSTFTPVDPAEIIARDSLCPLPSNGFSVKLFPRSYSLHTGNQVKKI
What is the function of this protein?
Catalyzes the conversion of 5-alpha-acetoxy-10beta-ol to 5-alpha-acetoxy-10beta,14beta-dihydroxy taxadiene.  Also acts on taxa-4(20),11-dien-5-alpha-yl acetate.
What are the official names of this protein?
Taxoid 14-beta-hydroxylase, Taxane 14b-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein.
Protein: TUSD_ECO81
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSSVFFYREGVYNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSNLQPGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y754_METJA
Sequence: MLEYISSLPKQPISEEEKEGLIEMREEEKLARDVYLTLYNKWKLQIFKNIAESEQTHMDAVKYLLEKYNIPDPVKNDSIGVFSNPKFEELYKKLVEKGDKSEVDALKVGATIEDLDIADLEKWINKTDNEDIKFVYENLMKGSRNHMRAFVRMLNNYGSNYTPQYISKEEYEEIISSSTERGMNR
What are the official names of this protein?
Uncharacterized protein MJ0754.
Protein: GSK3_SCHPO
Sequence: MNHGTKIPVDPFRIIKETARDGSTGEVKQLSYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQIKTMNPNYMEHRFPQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDELRDPNTKLHNSRNPDASPRHLPELFNFSPFELSIRPDLNQKLIPSHARDALPVKLDDFVPIPIHRARID
What is the function of this protein?
Interacts with cdc14 which is thought to play a role in the initiation and completion of mitosis.  Involved in the positive regulation of mis12.
What are the official names of this protein?
Protein kinase gsk3, Protein kinase skp1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: THIE_DEIRA
Sequence: MGWSGSPLTLPPLRGSPPLPQVERDRTQPQLLAFADAFPSEGRGELRSRERRGEATGRGGLRMTAPTRPLGHLYLVATPRPGQSEAEFLRRVEDALAGGVDTLQLRCKADSGQYGEARPYIALAERLRDLAHARNVPFFVNDRVDVALAAGADGVHLGQNDLPVEWARLMAPGLRVGRSTHRPEDAARALAEAPAYFATGPVHATPTKPGRVAAGLGYVRHIAALRPTLPWYAIGGIDLGNVQAVLDAGATRIAVVRAVLDADDCAAAAHALREALMVNG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: DNAK_UREPA
Sequence: MAKEIILGIDLGTTNSCVAVIENKKPIVLENPEGKRTVPSVVSFNGDEVLVGDAAKRKQITNPNTISSIKRLMGTKEKVTVLNKDYTPEEISAKILTYIKEYAEKKIGAKVNKAVITVPAYFDDAQRQATKNAGIIAGLSVERIINEPTAAALAYGIDKLDKEQKILVFDLGGGTFDVSVLDMADGTFEVLSTSGDNHLGGDDWDQVIINWLLKSIADEFNIDLSKNKMAMQRLKDAAEKAKIELSGINTTTISLPFIAMDSSGQPINFEKELNRATFDNLTKNLIERLKKPVLDAMKESKLSLVDIDQVLMVGGSTRMPAVQNLVKELTGKEPNHSLNPDEVVAIGAAIQGGVLAGEIDDILLLDVTPLTLSIETMGGVATPLIPRNTKIPVSKSQIFSTAADNQPSVDIRIVQGERSLAADNKLLGNFELSGIEPAPRGVPQIEIKFNIDANGIMSVNAKDLKTQKETSITIKDSQGLSQDEIDKMIKEAEENKEKDAKVKHERELVNRADSLINQLEQVSKTENVPQEQKDVFNKQIEDLTNARDAQDYVKLEAEVKKVEDLLTNAAKFAQQAQQQNPDNQNNNKDDVTEATVTDDSTKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CAIT_CITK8
Sequence: MKNEKRKSGIEPKVFFPPLIIVGILCWLTVRDLDAANIVINAVFSYVTNIWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFALAPGSNGAKEIGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMDVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQYLFGIPHTLELDAIIITCWIVLNAICVACGLQKGVKIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDAIGKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLMDKNILNIPQLIEQHGVARAIIETWAALPFSTATMWGFFILCFIATVTLINACSYTLAMSTCREVRDGEEPPLLVRIGWSVLVGVIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKVHWKDK
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ES1_DANRE
Sequence: MLASRALLAKQAAAMLVRQPACLMHHGGDWGNWGNTNIAVVFSGCGWWDGTDIHEAAYTMYHLSRNGARFQIFAPNQQQMHVMDHMKMQPSSSDNRNMMMESARFSHGQGMMQMNDLSKLDANSFDAVIFPGGHGIVKNMSTFSKDGKDCKLNNDVERVLKDFHRARKPIGLSSMAPLLACRVLPSLEVTMGYERDESSRWGRWPNTNMVQAVKSMGARHNTREPYEAYVDEKNKVISTPTFMWETDYHYHYIFDGIGNMVKHVMRMTAK
What is the function of this protein?
Plays a role in promoting mitochondrial enlargement in cone photoreceptor cells in a fusion-independent and ATP-dependent manner.
What are the official names of this protein?
ES1 protein, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion. Note=Colocalized with tom20 in cone mitochondria. Uniformly distributed throughout all mitochondria in cone ellipsoids including mega- mitochondria.
Protein: FLAB2_METJA
Sequence: MKVFEFLKGKRGAMGIGTLIIFIAMVLVAAVAAAVLINTSGFLQQKAMATGKESTEQVASGLSTLQVIGIHDNKAINYLAIYITPNAGSAAIDLNQTKILITDGEKKAVLRYNSNAYADLTTGGEVTNTSLAAWNLSGGEFGIIVLQDADGSCKSTTPVINKGDIVALTINASAVGLNLVPRTTVTGSVIPEFGAPAVIEFTTPAAYLSTQEVIQLQ
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
What are the official names of this protein?
Flagellin B2.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: C3H18_ARATH
Sequence: MNFTESMNVVHARIQQLEPENAAKIFGYLLLMQENGNRDMIRLAFCPDSVMCSVINCVKYELARNSHHYHSPPSDHIPTPKFGSFTGSSPLSVSVSPPMKTGFWENSTEMDTLQNNLQFLNFEDPLTSPEFSNGFFSQERQCLPLRTSRRSPSLPEFPVKICHYFNKGFCKHGNNCRYFHGQIIPERESFAQMFNPNNNLSDEEHVVSPVSLEKLEGEIIELLKLRRGAPISIASLPMMYYEKYGRTLQAEGYLTESQRHGKAGYSLTKLLARLKNTIRLVDRPHGQHSVILAEDASKFVEYTGERNEHGAILAGSRQIYLTFPAESSFTEHDVSIYFTSYGHVEDVRIPCQQKRMYGFVTFASSETVKHILAKGNPHFICNARVLVKPYREKSRSSRYLDNYKPLHGMRYGSKFIERDIEMNTLPPRVSESSRMRKPFLSEPEQSVSKSLPTNYSYLGFSSDDFKLTSNAEQEEQAERLSYLLDYLNTEDNVMNITTNYRDNDRRTHCESLDSQVLNLPESPFSSLSGKEISTVT
What is the function of this protein?
Possesses ribonuclease activity in vitro.
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 18, AtC3H18.
Protein: SA1B1_ARATH
Sequence: MDGDELTEQETALYDRQIRVWGAGAQRRLSKSHVLVSGIKGTVAEFCKNIVLAGVGSVTLLDDRLVTTEVFNANFLILPDENAYVGKTVAEICCDSLKDFNPMVHVSIEKGDLSTLGVDFFEKFDVVVIGYSSRATKKAVNEKCRNLAKDVAFYTVDCRGSCGEIFVDLQNYKYTKKKLDETVECELTFPSFEEAVSVPWKPMPRRTAKLYFAMRVIELFEETEGRKPGECSLSDLPRVLKLKKELCEGNSVSENHIPDILLERLVSNNTEFPPACAIIGGILGQEVIKVISGKGEPLKNFFYFDAEDGKGVIEDLSHKL
What is the function of this protein?
The dimeric enzyme acts as an E1 ligase for SUMO1 and SUMO2.  It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.  Functionally redundant with its paralog SAE1A.
What are the official names of this protein?
SUMO-activating enzyme subunit 1B-1, SUMO-activating enzyme subunit 1-2, Ubiquitin-like 1-activating enzyme E1A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_OENOB
Sequence: MAFNENRVINNYAEALMEVSGKQTAKVLSELQVIELVFERNKELAQTLDDVSVSSQQQEAFIGILGKGCSTTTKNFLETLADNRHFSLLEEIVENLDQRVSASNNHSLVIAKTAIPITAEQSKRLSKIAQKKFGYQHVEVKNVVDPNVIAGVILTAGSKTIDGSIKNKLVQLNNHIKQAVGKE
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ECFT_STAA4
Sequence: MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWVFALILFIMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVKRTSYRQLKWQLRDTISLTMIIPIAIILFVLKYSGV
What is the function of this protein?
Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YACG_PSEU2
Sequence: MSQPMTVQCPTCDAPVEWSAASPSRPFCSERCKLIDLGAWASEEHAIPVSPDAEDELFSGDLEAPHRGH
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: SECA1_MYCVP
Sequence: MLSKLLRLGEGRMVKRLKGVADYVNTLSDDIEKLSDAELRGKTDEFRARLAGGKEDLDDVMPEAFAVVREAAWRVLNQRHFDVQIMGGAALHFGNVAEMKTGEGKTLTSVLPAYLNALPGKGVHIVTVNEYLAKRDAEQMGRVHRFLGLDVDVILGTLTPDQRRAAYNADITYGTNWELGFDYLRDNMALRLEDCVQRGHHFAIVDEVDSILIDEARTPLIISGPADGGSNWYTEFARLAPLMKPDVHYEVDIKKRVVGINEAGVEFVEDQLGIENLYEAANSPLISYLNNAIKAKELFERDKHYIVRNGEVFIVDEFTGRMLVGRRYNEGLHQAIEAKEHVEIKAENQTVAQVTLQNYFRMYEKLAGMTGTAETEAAELHEIYKLGVVPIPTNRPMVRKDQSDLIYKTEEAKYIAVVDDVAERYEKGQPVLIGTTSVERSEFLSRQFEKRRIPHNVLNAKYHEQEAGIVAEAGRLGAITVATNMAGRGTDIVLGGNVDYLLDRRLRQRGLDPIETPEEYEQGWHEELPHIKAEVAAEAKDVIAAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLADELMRRFNGATLETLLTRLNLPDDVPIEAKMVSRAIKSAQTQVEQQNFDIRKEVLKYDEVMNQQRKVVYAERRRILEGENLAGQAHQILVDVITAYVDGATAEGYSEDWDLEKLWEGLRQLYPVGIDHHDLIDSDAVGEPGELTREELLQALIADAERAYAAREAEIEEIAGEGAMRQLERNVLLNVLDRKWREHLYEMDYLREGIGLRGLAQQRPEVEYAREGYDMFIAMLDGMKEESVGFLFNVQVERAPSAPTVAAQAAPAGLAAFAAAAAEQAQAQTGGVATKERPAVGGLRAKGIDDKAQPLTYTGPSEDGGVEVKRSGGGTPSTGGTRKERREAARQQKTGRHAKRR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: MUG14_SCHPO
Sequence: MAKVTGLPEFEDLHTKRKWMLNHMAAAFRMFGRNGYNEGTAGHVTVRDPIDENTFWINPLEVPFSLMKPSDLVHINSDGEIIGGSKMKYNTSGFAIHYEMHKVRPEVICVCHVHSIYGKAFSALGKPLDMLNTDCCVFYNNHGIYFDMDDVISMPEEGRRTAKGLADYKAVLVQNHGIMTVGTTVDEAAYLLSLMERSCQIQLLIDSATKVGERKHVHPTRAKAIRENADNPVGLYTAQQPNFLYEVACSNGELEII
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 14 protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MSCL_LACAC
Sequence: MLTEFKQFIARGNVIDLAVGVIIGAAFTAIVQSLVKNLINPLIGIFVGKIDLSNLVFKAGDATFKYGSFINSVINFLIISFVVFLIVKAVNKITKKEEEEKPDTPTETDYLKEIRDLLKEKETK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SEC13_CHAGB
Sequence: MIHDAVLDYYGRRLATCSSDRTIKIFEIEGETQRLTETLKGHDGAVWCVSWAHPKYGNILASAGYDGKVLIWREQNGAWQRIYDFSLHKASVNVVSWSPHEAGCVLACASSDGNVSVLEFKDNNSWEHSIFHAHGLGVNSVSWAPATNPGSIVSSKPSPKSTGNRRFVTGGSDNALKIWAFDAATGAYKLEREPLTGHTDWVRDVAWSPTVLQKSYIASASEDRTVRIWTSDPANPQQWNCKVLGFDAAVWRVSWSLSGNVLAASGGDNKVTLWKENLKGEWECVKSIEE
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: GATC_CHLMU
Sequence: MTQSYVNKEEIISLAKNAALELEEAHVEEFVTSMNNVIALMQEVVAIDISDIILEATVHHFVGPEDLREDMVTSDFTREEFLANVPVSLGGLVKVPTVIK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.