PharMolix/UniProtQA huggingface dataset:
Protein: SYH_XYLFM
Sequence: MIKPRTPPGVLELLPREQIAFQRMLDVIRRNYERFGFLPVETPVFELSDVLLTKSGGETERQVYFVQSTGTLANAAESGATRLPELALRFDLTVPLARYVAEYEHVLAFPFRRYQIQRVYRGERAQRGRFREFYQCDIDVIGKQTLSIRYDAEVLAVIHAVFSELGIGDFQVQLNNRKVLRGFLESQGVRDGELQLAVLREVDKLDKRGVLDVRDTLIGQGFGIPAAQVENILTFVATRSTSHADALARLDALIEDSGPGSHDMLRQGVAELREVLTLVNVLGVPEHAYRLNFSIARGLDYYTGTVYETSLINHPQIGSICSGGRYENLANHYTQSKLPGVGISIGLTRLFWQLRDAGLMDGIAESSVQAMVVLMDEATLDDALDIARCLRIGGINTEVQMEAKKVSKQFQYASRAGIRFVVLAGDDERARGVVAVKDLTREQQFEIPREELASTLQVELEQAKVM
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_LACAC
Sequence: MAKKVINVVKLQIPAGAATPAPPVGPALGQAGINIVGFTKDFNARTADQKGMIIPVVITVYEDRSFEFITKTPPAPVLLKQAAKIDKASGEPNTKKVGKVTKDQVKEIAETKMKDLNAADIEAAMRMVEGTARSMGIEVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: UCMA_DICLA
Sequence: MSWTRVVVLSSLTTLLILTFSSVVKSAAVRDDSKAGDPKGAARHVFMPESDASNFFKHRSRRSPRYYSERQAEQRVRLSANERRREYNEEQRNEFENYVEEERDEQNERSREKNEQVREYHYDGLYPRYHWFH
What is the function of this protein?
May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
What are the official names of this protein?
Unique cartilage matrix-associated protein.
What is the protein family that this protein belongs to?
Belongs to the UCMA family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HUTU_STAAC
Sequence: MRKIQAKKGLSIECKGWEQEAVLRMLYNNLDPEVAERPEDLVVYGGIGKAARNWEAFEAIEKTLRELESDETMLVQSGKPVAVFKTHEEAPRVLISNSVLVPEWANWDHFNELDKKGLIMYGQMTAGSWIYIGSQGIVQGTYETFAELGNQHFNGDLAGTVTLTAGLGGMGGAQPLAITMNHGVAICVDVDETRVDKRIDTKYCDVKTADLDEALKLAEEAKERGEGLSIGLVGNAVDIHQAILEKGFKIDIITDQTSAHDPLNGYVPQGYSVEEAKVLREKDPKKYVELSQASMAKHVELMLEFQKRGAVAFDYGNNIRQVAFNNGVKNAFDFPGFVPAYIRPLFCEGKGPFRFAALSGDPKDIERADEEMRKLFPENEKLLRWLDLAEEKISYQGLPSRIAWLGYGERAKMGLALNRLVRDGEISAPIVIGRDHLDAGSVASPNRETESMKDGSDAVGDWAVLNALINTAAGGSWISFHHGGGVGMGYSLHAGMVVVADGSERAERRLERVLTTDPGMGVARHVDAGYDIAIQTAKEKGIHIPMIDKAGDK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABD12_XENTR
Sequence: MRKRAEPVPPEHESFGRAPLDRECSIKQKLRIPGTKGHYPHDSDCDSKGMKRFGRRYGLWSRLRMFLIFLLGLYIAIPFLVKICPAIQTQLVFLNLVRFPYFIDLKRPEDQGLNHTCNFYLQPEEDVSIGVWHTVPAVLWKDAQGKDLEWYEEVLSTSYPVILYLHGNAGTRGGDHRVQLYKVLSSMGYHVISFDYRGWGDSVGSPSESGMTYDALHVFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDSLILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITASGIKFANDDNVKYISCPLLILHAEDDPVIPFHLGKKLYNIAAPARSLRDYKVQFVPFHKDLGYRHKYIYRSPELRQILRDFLGNTEQQ
What is the function of this protein?
Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity).  Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity).  Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal.  Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways.  Has a strong preference for very-long-chain lipid substrates; substrate specificity is likely due to improved catalysis and not improved substrate binding (By similarity).
What are the official names of this protein?
Lysophosphatidylserine lipase ABHD12, 2-arachidonoylglycerol hydrolase ABHD12, Abhydrolase domain-containing protein 12, Monoacylglycerol lipase ABHD12, Oxidized phosphatidylserine lipase ABHD12.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SYI_PROM4
Sequence: MTKETRQGEQNRPSYKESLNLLKTSFGMRANATLREPELQNFWADKGIDLELGLANKGPSFTLHDGPPYANGALHMGHALNKVLKDIINKFHIMRGHKVHFVPGWDCHGLPIELKVLQTLSNKERQALTPIQLRKKAAAYASKQVKGQMEGFKRWGIWGNWNKPYLTLQKEYESAQVKLFGQMVLKGYIYRGLKPVHWSPSSRTALAEAELEYPEAHTSPSVYVAFSVIHLPQSLSENLIKQGLELPGDEVELSKRLKVCIWTTTPWTLPANAAVSVNSNLDYSFVRHEEKGQILIFATELLEEVSEILGISFKQVANAKGESLKGILYKHPLYERTAPIVLGGSYITTQSGTGLVHTAPGHGIDDFKTGLQNNLEVFCPVDEKGIFTSEAGKFEGLNVLKDANKEIISSLEISGSLLKELPYVHKYPYDWRTKKPTIFRATEQWFASVEGFREDALKAIDDVEWLPESGRNRIQSMVRERGDWCISRQRTWGIPIPVFYKKNTNEILLNKETIDHIENLFAQYGADIWWEFDESKLLPPSLASESHHWQKGVDTMDVWFDSGSSWASVSCQRDELGYPADLYLEGTDQHRGWFQSSLLTSVAVNGHAPYKKVLTHGFALDENGRKMSKSLGNIIDPTVIINGGTNKKTDPAYGADVLRLWVSSVDYSVDVPIGSNILKQLSDVYRKVRNTSRYLLGNLHDFDPKKNSVDIDNLPILDKWMLNRTAEVIDEITLAFEKYEFSRFFQLLQSFCTVDLSNFYLDIAKDRLYVSAPDDPRRRACQTVMALIIEKLAGLISPVLCHMAEDIWQNIPYQLSEESVFKRGWPVSPSNWKRASLTEPISLIRELRTSVNRVLEGCRNRQELGSSLEAGLRLEITNQGLLDAIDFLAKNGDHDVDCIRDWFLVSQLQIGGEPWAEVLISQQFELGVIEISNARGYKCERCWHYEQDIGSCSEHPTLCGRCVTVMNRL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITD_STRS7
Sequence: MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNHIRALIKTTLANLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_PECAS
Sequence: MLKIFNTLSRQKEEFKPIHADQVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRYLGYSLKYVRNITDIDDKIIKRAIENGETSDQLTTRMIAEMHADFDALNILRPDAEPRATHHIADIIEMVETLITRRHAYVASNGDVMFSVDTASGYGVLSRQDLDQLRAGARVEITEVKRNPMDFVLWKMSKPGEPHWSSPWGEGRPGWHIECSAMNCKQLGEHFDIHGGGSDLMFPHHENEIAQSCCAHDGPYVNYWMHSGMVMVDREKMSKSLNNFFTVRDVLAYYDPETVRYFLMSGHYRSQLNYSEDNLKQARAALERLYIALRGTDPSVEAHGGDEFEARFHDAMDDDFNTPEAYSVLFDMAREVNRLKAEDVQAANQLASTLRKLSGVLGLLEQDPEQFLQNGAQVNDDEVKEIEALIQQRKDARATKDWALADQARDRLNEMGIVLEDGPQGTIWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_ROSCS
Sequence: MRNIALRIEYDGTDFVGSQWQTNGRSVQGALEAAWQQLTGERRRMILAGRTDAGVHARGQVANVSTNTRHSLATIIRGLNGVLPEDIGILAAWEVPEEFHARYSAVRREYRYVIDNGRTPSPLLRRHAAYVPRRLDVAAMDRAIQQVIGTHDFAPLSDGPQEGSTVRICYDARCTCTEVWGQPLVLIDVAANAFLRHMVRNLVGTLIQVGEGRIDADGFAAVLAGANRRARVLAPAHGLYLMAVRYPEDGNAAADTLVAAVGVTETRMQL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ACCD_CERDE
Sequence: MEKWWFNLILSNEELEHRCRLSKSMARPRPIGNTNGSQDPSINDRDKNGSDSGNYSFSNLDHLFDVKDNLSFIYDDTFLVRDSNGDSYSIYFDIENLIFEIDNDSFFLSKLESSFSNYLNSGSKNYNRYYDSYMYDTKYSWNNHINSYIDSYLCSEIRIDSYISSGIYNYSENYIYSYVWNGENVSTIKSRSSSIRTSANSSDINLKGRYNDFDINIKYRHLWVQCDNCYGLNYKKIFSSKMNICEQCGYHLKMSSSERIELSIDSGTWDPMNEDMVSTDPIEFHSEEEPYRDRIDSYQIKTGLTEAVQTGIGQLNGMPIAIGVMDFQFMGGSMGSVVGEKITRLIEYATNRSLPVIIVCASGGARMQEGSLSLMQMAKISSALYNYQLNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEYSFHKGLFDSIVPRNLLKGALSELLQLHGFFPLNHNSQVKR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: YM175_YEAST
Sequence: MNCLCLCSLYSKSISAYFSEFSSTNIYKSYLRLPSVLYYVCMMHTMMPNQLDAVGIQSSESLLM
What are the official names of this protein?
Uncharacterized protein YMR175W-A.
Protein: PTF1A_XENLA
Sequence: METVLEQLAGLESFPSPYFDEDDFFTDHSSRDALDADDFLEDDVDFLAGQIQDYYRDSRVLHTDDDYCDAGNFSFSSSSSGGFPYECGDGGCDLSPGMKGGSLVMKRRRRLRSDAEMQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSEMVQSDLPLRNPNSDSGNQPKKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLRDQNVVRTAKVWTPEDPRKLNKSPFSNIENEPPLTLCLDM
What is the function of this protein?
Transcription factor implicated in the cell fate determination in various organs.  Binds to the E-box consensus sequence 5'-CANNTG-3'.  Acts together with pdx1 to induce the pancreatic lineage within the endoderm.  Plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.
What are the official names of this protein?
Pancreas transcription factor 1 subunit alpha, Pancreas-specific transcription factor 1a, Transcription factor Ptf1a/p48.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPH_XYLFA
Sequence: MKVLLANPRGFCAGVDRAIEIVKRTIDMLGTPIYVRHEVVHNRFVVDDLKQRGAIFVEELHQVPDGATVIFSAHGVSQAVRRQAAQRGLKVFDATCPLVTKVHLDVARHCRTGRDMILIGHAGHPEVEGTMGQWDQERGTGRIYLVENIDDVATLHVAQPHHLAYTTQTTLSVDDTRNIIDALRQRFPTIQGPKNNDICYATQNRQDAVRELARECDLVLVVGSPNSSNSNRLSELAQREGVASYLIDSAAEIDPAWVIDKHHIGVTAGASAPQVLVDGVLARLYELGATSVSEHSGKPESMVFALPKALRLQLVD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RL34_ANADE
Sequence: MKRTYQPKKQRRNRTHGFLKRSKTPGGRNVLKSRRAKGRKRLTTRAPKK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ITRY_ACACO
Sequence: KELLDADGDILRNGGAYYILPALRGKGGGLTLAKTGDESCPLTVVQAQSETKRGLPAVIWTPPKIAILTPGFYLNFEFQPRDLPACLQKYSTLPWKVEGESQEVKIAPKEKEQFLVGSFKIKPYRDDYKLVYCEGNSDDESCKDLGISIDDENNRRLVVKDGHPLAVRFEKAHRSG
What is the function of this protein?
Inhibits trypsin and alpha-chymotrypsin stoichiometrically at the molar ratio of 1:1 and 2:1 respectively.
What are the official names of this protein?
Trypsin inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: PSRP_ECOL5
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILRSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: THIG_ACIBS
Sequence: MQDTPLIIGSRSFQSRLLVGTGKYKDLNETDLAIQASGAEIVTVAIRRVNIGQNPDQPNLLSVIPPEKYTILPNTAGCFDADSAVRTCMLARALLDGHNLVKLEVLGDEKTLYPNVTETLKAARTLIDDGFEIMVYTSDDPIIAQELESMGCVAIMPLGSLIGSGLGILNPHTISIIKENAKVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAAAQNPILMASAMKKAVEAGREAFLAGRMPRKRMANASSPETGYFFK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_HALHL
Sequence: MSELELAFQHVAGASAPEAERVQAWLEPVFEAHGRGGELTVRIVDEDESRALNRDYRGRDKPTNVLSFPCELPPGLPAEAAQILGDLVVCAPVVAREAAEQGKPEADHWAHMLVHGALHLLGYDHEDPAQAERMEAEERRILAALGVPDPYQER
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_LEPIN
Sequence: MNRSDLLENPRTQTESGFLLIHKPVGMTSSDLVVTVRKKLGFKKVGHTGTLDRAASGLMILPIGSCTSFSSVFLEKEKSYEAWVKPGESTDSGDKEGEILESLSKEQTETWFQEHQEKLRNLFEQVPTWETQEAPEVSALKVNGRRRSDLFREGVALVPVVRKIKIYRYELGKFSPESISFQIRVSAGTYIRKIVMDISDRIGFPLRLEKLVRTSIGKLNLNQADSYESLLDGKIKIHPPETILDFPTVEVPDTEVRNVLNGRKIKLEWIPVNEFLLVSPEEEILAWCKKEEHGIHELDYKYLRVFPKN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RS11_METVS
Sequence: MSQKWGLVHIYASYNNTILHVTDVTGAETIAKVSGGMIVRNQRDESSPYAAMQAAFKIAELMRDKGIDQVHVKVRAAGGQKSKNPGPGAQAAIRALSRAGIKIGRIEDATPIPHDGTTPKRKNR
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RL26_DICDI
Sequence: MKRNTNVSSSRRKSRKAHFTASSGERRIRMSAALSHDLRTKYNVRSLPIRKDDEVRVVCGDNKNHEGKVVACYRKKYVIHIDKLTVTKTNGNTAQIGVSPSNVILTKLKLDKDRKALLERKNRTVAADKGKVKVSADVN
What are the official names of this protein?
60S ribosomal protein L26.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SYFA_ENTFA
Sequence: MTLQAQLEALRDNTLKEIAQVATLKELNQIRVETLGKKGPITEVLRGMKNLSPEERPVVGGFANEIRDLLTEAIEARKVVLENEALNAALKEESLDVTLPGKQMPQGTRHILTQVMEEIEDIFLGMGYQVVEGYEVESDHYNFERMNLPKDHPARDMQDTFYISDEMLIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEGLVVDKNVTMGDLKGTLEVMMKKMFGEDRKIRLRPSYFPFTEPSVEVDVSCFKCGGAGCNVCKHTGWIEILGAGMVHPDVLQMSGIDPTEYSGFAFGLGPDRVAMLRYGVNDIRNFYQNDLRFLNQFKVKE
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP_SALAR
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILDRVETIRKLSKSSRAGNEANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPDLNDATIKKAVESLSLELVLTAHPTEITRRTLIHKMGEINNCLKQLDNTDIADYERHQVMRRLRQLIAQSWHTDEIRKQRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVDFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIHVLVSELSMVEATPELLALVGEEGASEPYRYLMKKLRARLMATQSWLEARLKGEKLPKPDGLLTQNEQLWEPLYACYQSLQACGMGIIANGELLDTLRRVKCFGVPLVRIDIRQESTRHTEALGEITRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWEPSNDTREVLETCKVIAEAPKGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNADDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEVTVSSLSLYTSAILEANLLPPPEPKDSWRHIMDELSVISCETYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFSKADLWLADYYDQRLVAKTLWPLGKELRDLLEEDIKVVLAIANDSHLMADLPWIAESIQLRNVYTDPLNVLQAELLYRSRLTEEQGKSPDPRVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: GLGA_STRA5
Sequence: MKIMFVAAEGAPFAKTGGLGDVIGALPKSLSKKGHDVAVVMPYYDMVDQKFGDQIENLMYFYTDVGWRHQYVGVKRLSQDNVTFYFIDNQYYFYRGHVYGDWDDGERFAYFQLAALELMEKIDFIPDVLHVHDYHTAMIPFLLKEKYHWIQAYNNIRAVFTIHNIEFQGQFGPEMLGDLFGVGAERYEDGTLRWNNCLNWMKAAILYSDRVTTVSPSYANEIKTPEFGKGLDQIMRMEAGKLSGIVNGIDSDLLNPETDAFLPYHFSKSNLEGKIKNKLALQENLGLPQDKNVPLIGIVSRLTDQKGFDIIASELDNMLQQDIQMVILGTGYHHFEETFSYFASRYPEKLSANITFDLRLAQQIYAASDIFMMPSAFEPCGLSQMMAMRYGSLPLVHEVGGLKDTVVAFNQFDGSGTGFSFNHFSGYWLMQTLKLALEVYNDYPEAWKKLQWQAMSKDFSWDTACVAYEQLYQQLQ
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RECC_BUCBP
Sequence: MFTLYKSLKFNLFVKSAFKVILNEPLLNPLTKEIFIVNNKETEQWIKIFIAKKYKVCTNIKFFKLKHFILNILKQNTPKLYSKSEFSKYSIMWKIINIPDIQHLLTKIVSKNNTYSTLFKIASSISNLFQLYLKYRPDYIKKWEQKSNIPKTRLKQKWQQIIWMRIIKYTKDANKPILHFSNLLYDSIKKMQRNNFINTKLPVRIFIFNITPITPQYAIFLKSISKYCSVHFFYATASYNDKQMFSTSFIKFKQTQEISNNQLLSLLHSKNKNIIYHEIENFQKNTKFQSYWITYEYEQMLFLSLIKDKTINLNFKIKQNSLLQYLQNKILNLHSIQKKNNEQENNKILILKTDKSLSIHSCHTLIREIEVLHNNLLNILNDNNDILFQDVLVISKNLDTYIPYINQIFNSASSKNFIPFSINYKNIKNIEFYKTILELIDLPNIELNINKITNLLNIPTLLKKVQINEQEIPILLQIINQTEIQWENDNILSNDWLSNDITKCWEHGLQRIFLGQIINNIDYKFWENIVPYNEFSTLYYNIFNKLISLISLLNKWKKILSKPKFLSHWDITFKKLLNDFFTDHEQKQPEAKLIIKKWTEIIHSGMQEKYTKKISITLLKNELCNSVSYISQSNYLFSGKITFCNNFTLTNIPFKIIYLIGLNDNISSNTHESFDIYNLLKLHPRAYDPCDEINHKNLLLKTLLSAKKFFYISHQIVSNNYKKLNNIPIAIDKIIKYITQYFYIKNKNKDNFNDNLKDIKSHIYHNYTFYAHEKRNFLEKLNYPNFNTTIWKMATLINNSHKEFIKKLPSIKNQTINYNTLILFWKNPIQTFFHVRLNIQLNTTKNKHMHQNKHFINKLDQYKMNKTLLKFFLYKQNTNQLFQYYKNIGIIPNNNIGNIIWEYTKKLITPLYDQIMKIKKILNNSKFCINVKNKCMLHGQLKNINSSGGLLRWKATKLSFQDIISCWLEHLLYCSLYKKHNSILIGTNHQIITFYKLENKTAKYYLKKYISGYFDGMEQPILLTKSGINWINAIYDKKNNKFYTNTNKNLNAYKIFLNTWNGNNWITGEKDDPYIQKMIVYLTKKNIQKIYKTTKKWLTPILKNISYSKYH
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
What are the official names of this protein?
RecBCD enzyme subunit RecC, Exonuclease V subunit RecC, ExoV subunit RecC, Helicase/nuclease RecBCD subunit RecC.
What is the protein family that this protein belongs to?
Belongs to the RecC family.
Protein: GRPE_LACJO
Sequence: MSKEEFPHEKDLKDEVTPDKAPKKDPKAAPKEEVKENPVENYEKEIAELTAKNKDLEDKYLRSEAEIQNMQARYAKERAQLIKYESQSLAKEVLPAMDNLERALAVKADDEAAKQLQKGVQMTLDSLVKSMKDQGITEIKAEGETFDPSLHQAVQTVAAENDERKDRVVKVLQKGYQYKDRTLRPAMVVVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_METBF
Sequence: MAKIIYDNETTFDALKDKTIAIMGYGSQGHAHARNLHESGLNVIVGLRKSSSSWAKAENDGLKVMTVAEAAKAADVIMILLPDENQASVYYSEIAPNLEAGNALAFAHGFNIHYNQIVPPKDVDVFMAAPKGPGHIVRRTYTEGIGVPALIAVYQDATGNAREIALSYVKGIGATRAGVYETTFREETETDLFGEQVDLCGGLSSLIKTAFETLVEAGYQPEMAYFETCHEVKLIVDLIYEGGLERMWHSVSNTAEYGGMTVGPRIINDESREAMREALKRIQNGEFAKEFVLEGMVNHPVLKAMERQEKEHQLEVVGKQIRANIPWLNREIDDD
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ISPF_CLOB6
Sequence: MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLN
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.