PharMolix/UniProtQA huggingface dataset:
Protein: VWC2L_MACFA
Sequence: MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQISSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKVCVTLHTY
What is the function of this protein?
May play a role in neurogenesis.  May play a role in bone differentiation and matrix mineralization.
What are the official names of this protein?
von Willebrand factor C domain-containing protein 2-like.
What are the subcellular locations of this protein?
Secreted. Synapse.
Protein: CATA_SOLAP
Sequence: MDPYKYRSSSAFNTPFWTTNSGAPVWNNNSSLTVGTRGPILLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFVRDGMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFTFLFDDLGVPQDYRHMEGSGVNTYTLINKAGKAQYVKFHWKPTCGVKCLLEDEAIKVGGANHSHATKDLYDSISAGNYPEWKLFIQIIEPDHEDKFDFDPLDVTKTWPEDIIPLMPVGRLVLNKNIDNFFAENEQLAFCPALIVPGVYYSDDKLLQTRIFSYADTQRHRLGPNYLQLPPNAPKCAHHNNHHEGLMNFMHRDEEVNYFPSRFDPVRHAERHPIPPPVLTGKRDRCMIEKENNFKQPGERYRTFAPDRQERFVCRWVDALSDPRVTHEIRSIWISYWTQADKSLGQKLASRLNVRPTM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PAPA2_MYCBP
Sequence: MFSITTLRDWTPDPGSIICWHASPTAKAKARQAPISEVPPSYQQAQHLRRYRDHVARGLDMSRLMIFTWDLPGRCNIRAMNYAINAHLRRHDTYHSWFEFDNAEHIVRHTIADPADIEVVQAEHQNMTSAELRHHIATPQPLQWDCFLFGIIQSDDHFTFYASIAHLCVDPMIVGVLFIEIHMMYSALVGGDPPIELPPAGRYDDHCVRQYADTAALTLDSARVRRWVEFAANNDGTLPHFPLPLGDLSVPHTGKLLTETLMDEQQGERFEAACVAAGARFSGGVFACAALAERELTNCETFDVVTTTDTRRTPTELRTTGWFTGLVPITVPVASGLFDSAARVAQISFDSGKDLATVPFDRVLELARPETGLRPPRPGNFVMSFLDASIAPLSTVANSDLNFRIYDEGRVSHQVSMWVNRYQHQTTVTVLFPDNPIASESVANYIAAMKSIYIRTADGTLAILKPGT
What is the function of this protein?
Catalyzes the acylation of trehalose-2-sulfate by adding the palmitoyl group at the 2'-position to yield the intermediate trehalose-2-sulfate-2'-palmitate (SL659).
What are the official names of this protein?
Trehalose-2-sulfate acyltransferase PapA2, 2-O-sulfo trehalose long-chain-acyltransferase, Polyketide synthase-associated protein A2.
What is the protein family that this protein belongs to?
Belongs to the PapA acyltransferase family.
Protein: OMPD_SALTS
Sequence: MRKHAKKIIRIIKMKLKLVAVAVTSLLAAGVVNAAEVYNKDGNKLDLYGKVHAQHYFSDDNGSDGDKTYARLGFKGETQINDQLTGFGQWEYEFKGNRTESQGADKDKTRLAFAGLKFADYGSFDYGRNYGVAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNTDFFGLVEGLNFAAQYQGKNDRDGAYESNGDGFGLSATYEYEGFGVGAAYAKSDRTNNQVKAASNLNAAGKNAEVWAAGLKYDANNIYLATTYSETLNMTTFGEDAAGDAFIANKTQNFEAVAQYQFDFGLRPSIAYLKSKGKNLGTYGDQDLVEYIDVGATYYFNKNMSTFVDYKINLLDDSDFTKAAKVSTDNIVAVGLNYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane porin OmpD.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: Y1363_MYCTU
Sequence: MAETTEPPSDAGTSQADAMALAAEAEAAEAEALAAAARARARAARLKREALAMAPAEDENVPEEYADWEDAEDYDDYDDYEAADQEAARSASWRRRLRVRLPRLSTIAMAAAVVIICGFTGLSGYIVWQHHEATERQQRAAAFAAGAKQGVINMTSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFTKVVEQSKVVTEGTVNATAVESMNEHSAVVLVAATSRVTNSAGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP
What are the official names of this protein?
Uncharacterized protein Rv1363c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1362c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACP_YERPA
Sequence: MSTIEERVKKIIVEQLGVKEDEVKNSASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDFINANQQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_MARMM
Sequence: MNMIEQLEQEEAARVLGEKTIPDFSAGDTLRVHVRIKEGERERIQVFEGVCIARNGGGLNESYTVRKISFGEGVERVFPLYSPNVEQIEIKRKGKVRRAKLYYLRDRRGKSARIAERVTGRGIEKREPKKKG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: NDOR1_ASPFU
Sequence: MSESPAQEARTRTALVLYGSETGNAQEVAEELGALAERLHFVTHVAEMNSVKATLLTILPQEMLRSFTFTIFVVSTTGQGEIPANARSFWRSLLLKKLPPTFLSGVNYVSFGLGDSSYPKFNWAARKLHKRLLQLGANEIYPRGEANAQHPEGLEGTFIPWITDFRSHLLDKYPLPEGLHPIPDDEQLPPKWVLRLQEPATTGDELTEGTLSSEQTVSDEYPGLTRLDHDVRPIPDALTATLVENRRVTPRTHWQDVRQISLTVPDAVTYAPGDMICITPKNFDEDVQALIDMMGWGEMADKLVSLAPGEKLQAAGELHAPPIPGLEKYPKLTLRALLMDYIDIRAIPRRSFFSAIAHYTSNEMHKERLLEFTNPEYLDEFWDYTSRPRRSILEVLHEFHSVKIPWQHVTTVFPVFRGRQFSIASGGELKRTSGGGAKFELLIAIVKYQTVIKRIREGVCTRYLSVLRPGSTLKVQLQRGGLSSSVNQLVGPTVLIGPGTGVAPLRSMLWEKAAFVKAYREEHPDANPPIGPTILLYGGRNRAADFFFEEEWQELSDLIGLQVFTAFSRDQRHKIYVQDIIRRNFGLFFRLLHDMNGSVYICGSSGRMPQAVREALIEAFEHGGQADGPQLARRGAEEYLIGMEKSGRYKQETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of dre2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: TSAD_ECO55
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_RHILW
Sequence: MKPRTPPDSPQLFQAVPLVPDFRLELKARKAGHWPVAGADEAGRGPLAGPVVAAAVILDPKRIPEGLNDSKQLSAQRREELFVQILATATVSIASSSSTRIDETDIRKASLDAMRRAICSLAIPASYVLTDGLDVPPGLDCPGQAVIKGDARSVSIAAASIVAKVTRDRMMARAHHVFPDYGFAAHVGYGTAQHRAGIEKLGPCSLHRMSFRPLRKVEDGPQMDELISE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_RHOCS
Sequence: MAIATADLFDSHEDILESCETQFRSYGGRAAFHGPIRTVRCHQDNALLKSLLSTPGDGAVLVVDGGGSLRTALVGDLIAGLGVKNGWAGIVVHGAIRDSEAIGGLDIGLKALGSNPRKSTKTGAGEADRPVAFGGCTFTPGHWLYSDADGVVVAPRRLHD
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: PDEI_ECOLI
Sequence: MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSWNPAYNCFDRPGKKCISFTLHINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYNSEGNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRRQFSEMTELVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIHKSAICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILGAEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTTIMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAGKIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE
What is the function of this protein?
Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG (By similarity).  Overexpression reduces biofilm formation.  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria (PubMed:19460094).
What are the official names of this protein?
Probable cyclic di-GMP phosphodiesterase PdeI.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YK35_SCHPO
Sequence: MRFLFFLPPSFITSFLYLALYSFPVPYCII
What are the official names of this protein?
Putative uncharacterized protein SPAC110.05.
Protein: LGC4_CAEBR
Sequence: MVICHSCTTFCILLVIDLVPCRIVGMENVENRVMFSLLDRSPQTNDTGPKPEKFEIAKGKFKVLEENSIGADTVSHLPTTREEHVSAVVPMPNFDPHRLEKALRTKGSIDGTEEALYRSLLDHTVYEKDVRPCIHHSQPTNVTFGFLLNQIVEMDERNQALTTRSWLNINWMDPRLSWNESLWSDIKAIYIPHARIWKPDIILVNNAIREYYASLVSTDVMVTSDGNVTWLFSALFRSSCPIRVRYYPFDDQQCDLKFASWSHDITEINLGLNTDKGDLSSYMNNSEFDLVDMTAVREVVRFPSDTNSDWPTIVIRIHMHRRPLFYVFNHIVPCVLISSMAVLGFLMPPETGEKINMIITTLLSMGVYLQSITESIPPTSEGVPLIGMYYVSSLLMVCLATCVNVITLNMHRNGAANQGRHVPAWMQKWILGYLATFMRMSIREPDSIALLKASQSKKSTIRRSSILRDLKRVKNMSNVRAKSKEQNANRECECMDPLVHIYAESIMTSLVSDPKPMNGSTIREDFASESTFLGRVVSDGIMPRISASSNSVLTEFETRFRRILKRVYRSLQQHEIREEILDERSRIQWQWQQLASVVDRLLLCLFCTATLFTIICLLIVPVVYRDNDVLSILNFF
What is the function of this protein?
Acetylcholine receptor.
What are the official names of this protein?
Ligand-gated ion channel 4.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: PUUD_SHIFL
Sequence: MENIMNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIALPHALAEPSLLEQLLPKLDGIYLPSSPSNVQPHLYGENGDEPDADPGRDLLSMAIINAALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQVEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALGVQWHPEWNSSEYALSRILFEGFITAWQHHIAEKQRL
What is the function of this protein?
Involved in the breakdown of putrescine via hydrolysis of the gamma-glutamyl linkage of gamma-glutamyl-gamma-aminobutyrate.
What are the official names of this protein?
Gamma-glutamyl-gamma-aminobutyrate hydrolase, Gamma-Glu-GABA hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C26 family.
Protein: RS19_NEIMA
Sequence: MARSLKKGPYVDLHLLKKVDAARASNDKRPIKTWSRRSTILPDFIGLTIAVHNGRTHVPVFISDNMVGHKLGEFSLTRTFKGHLADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FETUA_SHEEP
Sequence: MKSFLLLFCLAQLCSCRSIPLDPIAGYKEPACDDPDTEQAALAAVDYINKHLPRGYKHTLNQIDSVKVWPRRPTGEVYDIEIDTLETTCHVLDPTPLVNCSVRQQTEHAVEGDCDIHVLKQDGQFSVLFTKCDSSPDSAEDVRKLCPDCPLLAPLNNSQVVHAAEVALATFNAQNNGSYFQLVEISRAQFVPLPGSVSVEFAVAATDCIAKEVVDPTKCNLLAEKQYGFCKGSVIQKALGGEDVTVTCTLFQTQPVIPQPQPEGAEAGAPSAVPDAAVPDAAVPAPSAAGLPVGSVVAGPSVVAVPLPLHRAHYDLRHTFSGVASVESASGEAFHVGKTPIVGQPSVPGGPVHLCPGRIRYFKI
What are the official names of this protein?
Alpha-2-HS-glycoprotein, Fetuin-A.
What is the protein family that this protein belongs to?
Belongs to the fetuin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AGAL1_PEDPE
Sequence: MSLITVDQANRVFHLHNQTLSYIFAVEQGGTLSHLYFGGHVDHYHGELRYPRVDRGFSGNLPGSTDRTFSRDTLPKEYSTAGEMDYHLPAAIVRHTDGANALYLVYQGYRIEAGKPKLSGLPAAFVEDETEAETLTIVLVDQVSQVEFDLQYTIYRDRPVVTRSVQVCNQGDHAVNLEKVASMQIDFTDRQFETITLPGAHANERHPERGSINYGIQTFGSLRGTSSHQMNPFLALVDHTTTEFSGDAYGFNLVYSGNHAFELEKDQLDQLHLMVGINSYNFNWQLKAGATFQTPEVLMVYTNKGLNAMSQAYHHLIRERVVRSEFKNQERPIVVNNWEATFFDFNEAKLKPIVDEAKQLGIEMFVLDDGWFGHRDDDNSSLGDWQVDHRKFPQGLNHFVKYVHEQGLKFGIWLEPEMISYDSKLYQQHPDYLMQVPGRSPSPSRNQYILDLGRQAVRNNIFDQLDQLLKSKQIDYIKWDMNRHLSDIYSVALPPERQGEVYHRYVLGLYELLERLTTAYPHILFEGCSGGGGRFDAGMAYYMPQIWASDNTDAVARLTIQYGTSLAYPISLATAHVSVSPNQQTGRETSMSTRSAVAASGVLGYELDLTQLSSADKQIVQKQVVQYKQIRPLIQFGEFYRLKSPITSNQAAWMFVSPQQDEAIVMVFNLTSYAQPSLTKTKLVGLNPKLNYQNIATKAIFGGDELMQLGFYDPVVYQDYTTKVYHFKAVTEN
What is the function of this protein?
Alpha-galactosidase associated with the raffinose operon.
What are the official names of this protein?
Alpha-galactosidase 1, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 36 family.
Protein: PESC_RAT
Sequence: MGGLEKKKYERGSATNYITRNKARKKLQLSLPDFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIKFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNAVERLKDNKPSYKLDHIVKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYVIAARALRKVFLSIKGIYYQAEVLGQPIVWIAPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKIESQAQAEMKVSEDTYALDSESSMEKLAALSASLARVVVPAVEEAEADEFPTDGEVTAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGDVSWDKSLCIGATYDSTDSGITHQIVDRPGQQTPIIGRYYVQPQWVFDCVNARLLLPVAEYFPGVQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGNLEEEEEDEDDEGDDSEGDGDVAVENEEEVVEAESEEEEEAHLSALEQQRLGGKKPQVMAGTVKLEDRQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREANKLAEKRKAHDDAVRSEKKAKRTRPV
What is the function of this protein?
Component of the PeBoW complex, which is required for maturation of 28S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.
Protein: RL33_BORT9
Sequence: MGKKKGKGAVELIALVCEETGIRNYTTTKNRRNKQEKLELMKYCPILRKHTLHKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: Y216_LISMO
Sequence: MRLDKYLKVSRLIKRRTVAKEVAEKGRIAVNGVTAKPGTNVKSGDELVIRFGPKIVTAKIERLEENAKKEQATEMYTIIKEERTDESR
What are the official names of this protein?
Uncharacterized protein Lmo0216.
Protein: CLPP_HISS2
Sequence: MSVIPMVVEQTSRGERSYDIYSRLLKERVIFLTGEVEDRMANLIVAQLLFLEAEDPAKDINIYINSPGGSVTAGMAIYDTMQFIKPNVRTLCIGQACSMGAFLLAGGTAGKRAALPHARVMIHQPLGGFRGQASDIQIHAQEILKIKQTLNERLAFHTGQSIEQIEQDTDRDNFMSAEQAKLYGLVDDVLIKR
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_RHIE6
Sequence: MQSITIRRPDDWHLHLRDGAMLEGVIADTSRTFARAIIMPNLVPPVVTTSDATAYRDRILKALPAGHHFQPLMTLYLTEHTSPDDVEAGAKSGLITAVKLYPAGATTNSHGGVRDLEKAMPVLERMARIGLPLCVHGEVTTPEVDIFDREAVFIDTVLDPLRKRLPELKVTMEHVTTADGIDYIKAAQSNLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRENHRLALRAAAVSGDARFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEEEGALDKLEAFASLNGPAWYGLSPNEERITLSRQAEPVVFPAKIETGAGPVTVFDPMFPLHWQVMPQA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: NOP16_KLULA
Sequence: MASVRKRKMAKSSVKKVSRRNKDKQKQVNIKGNPIIAENWDYSLTLAQNYKKLGLKVKMGKFAGGEEADLSKVIKKDVYEHSAFSDDESEDEKDSQGEEDEDDVNLEELNSDGEYDESKIPEGEARIKRDDDGNIVKVYYGKRKAIDIDMDVEELRRENEKNEVKTEVVKKLEAYASRPVAKKERGLSQREDQWLEQLYKKHGDNYKKMFFDKKLNVYQQTENVLRRKILKWKELHNIE
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar protein 16.
What is the protein family that this protein belongs to?
Belongs to the NOP16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y703_HAEIN
Sequence: MKIFGTMYDKTMEWSKHRFAVFWLSFVSFIEAIFFPIPPDVMLIPMSMSKPKSAVKFAFYTAIASVIGGIIGYAIGFYATDWVENIVQQWGYAAHWAKAVSWFEQWGVLVVFVAGFSPIPYKVFTLCAGVMQMAFFPFVITAFVSRLARFLLVAKLAAWGGEKFAAKLRKSIEIIGWSVVVLAVIAYFILKN
What are the official names of this protein?
Uncharacterized protein HI_0703.
Protein: CARB_CLOAB
Sequence: MPLDKTIKKVLIIGSGPNNIGQAAEFDYSGTQACKAVKEEGIETVLVNSNPATIMTDSHIADKVYIEPLTEEAVEKIIEKERPDGILAGFGGQTALNLAMNLNDAGVLDKYNVRLLGINSEAIKKAEDREEFKNLMEEIDEPVPKSIIATHIDECIDFVNKFGLPVIIRPAFTLGGTGGGIASTMEELKEICDRGIKMSPIGQILLEQSVAGWKELEYEVMRDAKDNCIIVCNMENLDPVGVHTGDSIVTAPSQTLTDKEYHMLRHSALKIIRNLKIEGGCNIQFALNPKSNDYIVIEVNPRVSRSSALASKAAGYPIAKIAAKIAVGYSLDELKNYVTKNSSACFEPALDYVVVKIPKWPFDKFNTAERHLGTQMKATGEVMAIDRDFESALLKAVTSLEGKISGLRLEKFEYTTVRELLEKIKKQDDERIFAIAEAFRRGVDVKQIHEVTEIDNWYLNGINRIIDMEKELQDKNNKDKDKSIIKAKKMGFTVAEIARITSLEEGKIKNILNVNNVKPVFKMVDTCSGEFEAETPYYYSSYENEDENEVTDDKKIVVIGSGPIRIGQGIEFDYCCVHGVWAIKEAGYKSIIINNNPETVSTDFDTADKLYFESLYIDNVMNIIEKEKPEGVIVQFGGQTAINLADKLYKNGVKILGTSFESIDLAEDREKFSELLKELNIPQAKGMAVTSMEEAYEAVKEIGYPVIVRPSYVIGGRAMQVVYDKLALQKYMTEAVTLSTEHPVLIDKYIKGTEIEVDTISDGENILIPGIMEHIERTGVHSGDSITMYPYHTLPKEVVDKLVKYTKSLAKALEVKGLMNIQYVYDGENVYVIEVNPRASRTVPILSKVTGVPMVKLAVEILTGKNLKELGYGVDLKKDNKLYAVKVPVFSNEKLANVDIYLGPEMRSTGEVMGIDSDFEVAIYKGFRAAGIEVPKDGGNLYVSIKDVDKQESVPIIKKYTEFGYKIYASLGTGKFLQKQGIDCEVLRTDDLMKAIGDGKINLIINSPTRGNTVGTRGFSIRRKAAEYKVGAFTCIDTAKAFLTAIKVKREEAKVEYRAMKEYFK
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: PURA_STRT1
Sequence: MTSVVVIGTQWGDEGKGKITDFLSQDAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGVFFPEKISVIGNGVVVNPKSLVKELEYLHTEGVSTENLRISDRAHVILPYHIKLDQLQEAAKGDNKIGTTNKGIGPAYMDKAARVGIRIADLLDKEIFASRLKTNLAEKNRLFSKMYESEELSFDEIFEEYYAYGQQIKQYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNCIDVLSGLDTVKICVAYDLDGERIDYYPASLEQLKRCKPIYEELPGWEEDITGCRSLDELPENARNYVRRIGELVGIRISTFSVGPGREQTNILESVWSNI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAA_STAA1
Sequence: MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNNIKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTKDNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRVSKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFILGTYRIPAMKSTENGDFAGYLKFDFRQSNSETVDVTEDFEEANITVTLKGDTKLNDSSKKVTINDREMAFSSSKTYGPYPQNKDITISASGKAKGKTFTTQTKTIKASDLKYNTEITLNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSSFYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQDRLQLIKTSEK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACEK_PSEPG
Sequence: MTQHWPAGEIARMILDGFDDYREHFRRITLGARERFEQARWQDIQRAAAARINLYEQKVGEVNGWLRDAFDDEVLLEVEQWPLVKSAYIRLIDPRLDDELSETWYNSLFCSLFSHDQISDGCMFIHTTRPSIRSHQRAAQTRTYCLDASLQSLLRAIFADYAFAYGDLESDVSRLEAQLREHLPDWVCKDSTLTVELFSPVLYRNKGAYLVGRLYNSDEQWPLVIPLLHREGHGVEADALITDEAEVSIIFSFTRSYFMVDVPVPAEFVNFLKRILPGKHIAELYTSIGFYKHGKSEFYRALINHLANSDDRFIMAPGVRGMVMSVFTLPGFNTVFKIIKDRFSPSKTVDRATVIDKYRLVKSVDRVGRMADTQEFADFRFPRDKFEPECLAELLEVAPSTVVLEGDTVLIRHCWTERRMTPLNLYLEHASEGQVLEALEDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEISFLTEVNFRHIPPPRYPEDEMSGEPWYSIGPHDVFPEEFPPFLFADMGQRRLFSRLHGELYDADYWKGLQAAIREGKVIDVFPYRRKGR
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.