PharMolix/UniProtQA huggingface dataset:
Protein: DCTA_VEREI
Sequence: MTKAPLHKSLYVQVLAAIVIGVVLGHFYPPSGEAMKPLGDGFIKLIKMIIAPVIFCTVVLGIAGMEDMKKVGKTGGLALLYFEIVSTLALIVGLVLVNVLQPGAGMNIDPRTIDTKAITAYTGPGKMTGTVEFLLNIIPVSMVDAFAKGDILQVLLISVLFGFALHRFGGRGTMVFDFIEKVSQVLFAIVGTIMKAAPIGAFGAMAFTIGKYGIGSLLSLGKLMGTFYLTCLFFIFAVLGTITRLHGFSVWKFVKYIKEELLIVLGTSSSESVLPRMLSKMENLGAKKTVVGLVIPTGYSFNLDGTAIYLTMAAVFIAQATNTPMTLMQEVTLLAVLLLTSKGAAGITGSGFIVLAASLSAVGHLPVAGLALILGIDRFMSEARALTNTIGNGVASIVVAKWSKELDEQRLHAQLNGQTAEEASAPQALPDRMESRIHH
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CXB1_HORSE
Sequence: MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDHFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPIHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAAFMYVFYLLYPGYAMVRLVKCDAYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIVRACARRAQRRSNPPSRKGSGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction beta-1 protein, Connexin-32, Cx32.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Beta-type (group I) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: ADDA_STRPI
Sequence: MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNILVSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQETDDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLENEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWLSDSFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEIGSLNQESDSQAYQAVLAHVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQFAKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVGEINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEILKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMASSQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLPRFIRMIDQVLEAQHDLASVVVAPPKDAVELMTIHKSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQDSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLILLGKDEVQVVKV
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: ATNK_EMENI
Sequence: MINQTAMLLTRSLRPRSAFVGAGLGYPRRFLTTVESPLHEFFVVIFNKRNAKESDLAPAPQTIKFKEQDVILTFAGDMMASAAPATDSAPERTLGACFRVPGTQRAESVAGDSRPREHRQGAVGY
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of aspercryptins, linear lipopeptides built from six amino acids including 2 highly unusual and nonproteogenic amino acids, 2-amino-octanoic acid (2aoa) and 2-amino-dodecanol (2adol) (PubMed:23248299, PubMed:27310134, PubMed:26563584).  The core structure of aspercryptins is as follows: Ser/Ala-Thr-Ile/Val-2aoa-Asn-2adol (PubMed:27310134).  The first step of aspercryptin biosynthesis is the generation of the fatty acid precursors, octanoic and dodecanoic acids, by the FAS subunits atnF and atnM (PubMed:27310134, PubMed:26563584).  The fatty acid precursors are likely transformed into the corresponding alpha-amino fatty acids in three steps (PubMed:27310134, PubMed:26563584).  First, they are hydroxylated by the cytochrome P450 monooxygenase atnE, then oxidized to the corresponding alpha-keto acids by the NAD(P)-dependent oxidoreductase atnD, and finally converted to the alpha-amino fatty acids by the PLP-dependent aminotransferases atnH or atnJ (PubMed:27310134, PubMed:26563584).  the alpha-amino fatty acids, 2-amino-octanoic and 2-amino-dodecanoic acids, are recognized, activated, and covalently tethered to the NRPS atnA by its fourth and sixth adenylation domains (PubMed:27310134).  The second module of atnA is the Thr module and contains an epimerase (E) domain responsible for the epimerization of Thr to D-allo-Thr (PubMed:26563584).  Additionally, despite atnA having only one epimerase domain, the first amino acid of aspercryptin A1 is D-Ser, suggesting that serine is either loaded directly as D-Ser on the first module or that the epimerase domain in the threonine module epimerizes both L-Ser and L-Thr (PubMed:27310134).  After condensation of the hexapeptide of aspercryptin, the C-terminal reductase (TE) domain might be involved in the reductive release and production of the aldehyde hexapeptide (PubMed:26563584).  Further reduction would generate aspercryptins (PubMed:27310134, PubMed:26563584).  The variety of aspercryptins produced reflects the flexibiliy of the atnA NRPS, allowing incorporation of alanine instead of serine, valine for isoleucine, and a C10 fatty amino alcohol instead of the C12 version (PubMed:27310134).  AtnB seems to be involved in the selectivity for Ile versus Val by the third module (PubMed:26563584).  Moreover, type B, C and D aspercryptins have an additional N-terminal cichorine, acetyl and propionyl group respectively (PubMed:27310134).
What are the official names of this protein?
Aspercryptin biosynthesis cluster protein K.
Protein: CLPQ_BACLD
Sequence: MSSFHATTIFAVQHNGKSAMAGDGQVTFGQAVVMKHTARKVRKLFNGKVIAGFAGSVADAFTLFEMFEAKLEEYNGNLQRAAVELAKEWRSDKVLRKLEAMLIVMNADSMLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKRHAGSQLDAKAIARASLETAGEICVYTNDQIIVEELE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex.
What are the official names of this protein?
ATP-dependent protease subunit ClpQ.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_PHYMT
Sequence: MIFQKIQEFIAEQLSIDKNNIKLESDLKEDLGIDSIDAVGLIIKIEEFFKLEVSDETLQKFKNVKDILEYIQQHVDNYDYLEKK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_LACLA
Sequence: MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGLTGIAVNGNVAAIVELNSETDFVAKNDQFVALVKETAELIASKKPATNEEALALETASGITLEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGGKIGVVSVVEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEFGSKSQLTEEVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEVGEGIEKAETDFAAEVEAAKAGL
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_BORA1
Sequence: MNTPPLICLAGPTAAGKSAATLALAERWPLEIINVDSATIYRGMDIGTAKPSAAEQAQVAQHLLDIRDPSQAYSAADFRTDTLALIEDIQARGRIPLLAGGTMLYYKALREGLDDLPQADPVLRAELEARAANEGWPALHAELARHDPITAARLSPNDSQRIQRALEVCLLSGRAMSALLTGTRRPAPSDLRFVTISLEPSDRAGLHARIAQRFDAMLQAGLEAEVRSLKQRTDLHPGLPSVRCVGYRQMWAYLDGEVSFDEAREQGIAATRQLAKRQLTWLRAQPERVIVDCLAAGTAARVVDIAARYLPG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: G6PI_GEOKA
Sequence: MTHIRFDYSKALAFFGEHELTYLRDAVKVAHHSLHEKTGVGSDFLGWLDWPVDYDKEEFARIKEAAKKIQSDSDVLVVIGIGGSYLGARAAIEMLHHSFYNALPKEKRKTPQIIFVGNNISSTYMKDVIDFLEGKDFSINVISKSGTTTEPAIAFRIFRKLLEEKYGKEEARRRIYATTDSKRGALRTLANEEGYETFVIPDDIGGRYSVLTAVGLLPIAASGADINAMMEGAAKARDDFSSSELEENAAYQYAAIRNILYNKGKTIELLVNYEPALHYFAEWWKQLFGESEGKDQKGIYPASADFSTDLHSLGQYIQEGRRDLFETVLKLEEPRHELIIEAEENDLDGLNYLAGKTVDFVNTKAFEGTLLAHTDGGVPNLVITLPKLDEYTFGYLVYFFEKACAMSGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEQLKEELEKRLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_PROMH
Sequence: MSGITAALVKELRERTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEGIILAEVAADGKFGALVELNCETDFVAKDAGFIAFGKDVMAAVLADKTDDIEALKAKFEDARTALVAKIGENINIRRVAILEGEELGTYLHGARIGVLVAAKGANEELIKHIAMHVAASKPEYVRPEDVPADVVEHEHQIQMDIAMQSGKPREIAEKMVTGRMNKFTGEISLTGQHFVMDPSKTVGDLLKENNAEIINFVRFEVGEGIEKVEADFAAEVAAMSK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_CYCTA
Sequence: MDIVSIAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YEGS_SHEFN
Sequence: MPLTHIRLLLNGKKATNVDIRQSVIALREQGHTIDVRVSWESADMLRFITEAIADNVGRVVIGGGDGSLNEAVNALMQQPQQDHKLEIAVLPLGTANDFATACGISNIIQSTLELAIHGDSYPIDIIRANNNYFINAAVAGFGAQVTAETPTELKDFLGGGAYTLVGLAKALGFKPYQGSITTDKGTFNGDIVVGAICNNKQAGGGQMLAPNALIDDGLMDITLLKSFSTFDIPVVLDEIQAMSHEAKFCYHFQTRWLEIDFPIKLPLNLDGEPYPTKKMRFEVLPKAIQFVLPPNCPCLVQSTQKSGI
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS-like.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_RICPR
Sequence: MNIDKFTAHAKSVIANHQSLAIKNDHQQILPLHLLSSLLSEETGIIQALINNIGGNINLLKDQVQLELNKIPKIQVDGGGQIYYSAEDLKVLEKSSSIAKDSGDSFVTIERIFEALTYDNTIAGKILTNNGINSKKLATAILHLRKGKKADTESAENNYDALKRYGRDVTELAENGKLDPIIGRDEEIRRAVQVLSRRMKNNPVLIGAPGVGKTAIIEGLAQRIFSKDVPETLINCRIIELDIGALIAGAQYRGEFEKRLKAVLSEIKESSGEIILFIDELHLLVGTGKVDGAMDASNLLKPMLARGELHCIGATTLDEYRKYIEKDAALARRFQPVYVGEPSVEDTISILRGIKEKYELHHAVRISDSAIVAAATLSNRYITDRYLPDKAIDLIDEACSRMKIELSSKPEELDELDRRIIQIKIELAALKKENDEHSKKKITSLTEELKKLESKSYDMNTKWQAEKSKLQQAQKLKEELEQARIDLERAERDANLAKASELKYGIIPEIMNKLQEAENMDNKGLLKEIVSESDIASIISRITGIPIDTMLSSERERLLVIEQKLCESVIGQDEAIKGVSDAVRRSRSGIQDINRPLGSFLFLGPTGVGKTELTKALAGFLFDDRNALLRIDMSEYMEKHSISRLIGAPPGYIGYDQGGVLTESVRRRPYQVILFDEVEKAHLDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLGAEILVNQKEGEDTYKVRDEVMQYVRAVFKPEFLNRLDEIILFHRLNRNNIHDIVKIQLGSLKKILLQQNIILEFDESALNYLAEKGYDPSFGARPLKRLIQREIQNNLAKMILAGEISSGNTVKIRREKEELSINIID
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_BACTN
Sequence: MNLIIDIGNTTAKVALFNRSEMVEVLTESNQSLDSLEALCSKYRIERGIVATVVDLNERILAELAALPFPLLWLNHETPLPVGNLYETPETLGYDRIAAVVGANEQFPHNDILVIDAGTCITYEFIDSKGQYHGGNISPGMQMRYKALHQFTGRLPLIDSNGRKLPMGRDTETAIRAGVLKGMEYEISGYIEAMKHKYPELLVFLTGGDDFSFDSSVKSAIFADRFLVLKGLNRILNYNNGRI
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASF2_YEAST
Sequence: MPKNRGVLDAITRSVIDGSDQESSSSFNSDKEYAAVTKGLSSSRVQKKSSLRQMKSKVKELQSLVNHYRENEAALVSSAKLLSGEIIGYEIKMASLHGKMKSILDENNALKETHKSSAEKRIELVRLPSSKEERNYDEYTLLVNLKKEICAKLQDYKNVQNTVNTKLDEIHTFHEKYYEGLELSLDSKVFDAESSKELAKVRRELNNVRKNSEIKVNNLKMQLLQATKSLEHLKKQAKAKDDYLKCIPELVDKANLTMLSYKKSIANQRETIEALQAELSQQSETKGQIETETQNQVQIPTNVTLVDPFEENNPEDLFAIQEQELQDLRLHKKMADERSRTTHLHLERKNNTIKLLQSYVQSLIQRLPPAQRKHHLGIFQKLGSEKSCPLAPAVASTYAPLLLLSQHSNHQEIDNTPQRLLLAAPDGQSYSEKSTTLNLDYSSRKSYLSRLQPPHIANLKSLTLKTLPRVPTDSPQLPSKDKSQETAKKDDRPKLVANEPVTLDTSTPPVAQSLADSKHCSGLHK
What is the function of this protein?
Derepression of silent mating type loci when overexpressed.
What are the official names of this protein?
Anti-silencing protein 2.
Protein: VINT_BPP2
Sequence: MAIKKLDDGRYEVDIRPTGRNGKRIRRKFDKKSEAVAFEKYTLYNHHNKEWLSKPTDKRRLSELTQIWWDLKGKHEEHGKSNLGKIEIFTKITNDPCAFQITKSLISQYCATRRSQGIKPSSINRDLTCISGMFTALIEAELFFGEHPIRGTKRLKEEKPETGYLTQEEIALLLAALDGDNKKIAILCLSTGARWGEAARLKAENIIHNRVTFVKTKTNKPRTVPISEAVAKMIADNKRGFLFPDADYPRFRRTMKAIKPDLPMGQATHALRHSFATHFMINGGSIITLQRILGHTRIEQTMVYAHFAPEYLQDAISLNPLRGGTEAESVHTVSTVE
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: NODD2_BRAJP
Sequence: MRFKGLDLNLLVALDALMTKRSVTAAARSINLSQPAMSAAIARLRTYFGDDLFTMRGRELIPTPRAIALAPAVRDALLHIQFSIISWDMFNPVQSQRRFRIRLSDVIMLVFFERVVKRLAREAPGIGFELLPLTEDPDELLRYGDVDFVILPELFASSDHPKAKLLDDTLVCVGCPTNKQLKRQLSFENYGSMGHIAAKFGRTLKPSIENWLLLEHGLKRRIEVVVPGFSLIPPLLSGTDRIATMPLRLVEHFAKTTPLRVAELPLALPPFAQAVQWPSLHNRDQASIWMRQVLLQEALHMTTPPDSVEYRP
What is the function of this protein?
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D 2.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: QUEA_HAEIG
Sequence: MRVSDFNFDLPDELIARYPKTDRVSCRLLQLNGENGEIFHRTFSDVLDLIDEGDLLIFNNTRVIPARMFGRKASGGKIEVLVERMLDEHRFLAHIRSSKSPKEGAELFLGEDKLGENNGIKAVMKARHSSLFEVELSDKSTALLDVLQTIGHMPLPPYIDRPDEEADKECYQTVYSKVPGAVAAPTAGLHFDENLLEKLKAKGVNFEFVTLHVGAGTFQPVRVENIEDHVMHAEYVEVSQEVCNAIIATKKAGKRVIAVGTTSVRSIESAALSAEEFGNPDLIEPYFSDTSIFIYPGKKFRVVDCLITNFHLPESTLIMLVSAFAGYKNTMNAYKHAVQEKYRFFSYGDAMFINKNSNVRGLE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABITM_DANRE
Sequence: MEDKEEKKAPSVIDRYFTRWYRTDLKGKPCEDHCILQHSNRICVITLAESHPIFQNGRKIKNINYQISDGCSRLKNKVSGKSKRGGQFLTEFAPLCRITCTDEQEFTIFSCIRGRLLEVNEVILNKPDLLMEKPSTEGYIAVILPKFEESKSVTEGLLTREQYEEILTKRNQQEVPC
What is the function of this protein?
May regulate actin polymerization, filopodia dynamics and arborization of neurons.
What are the official names of this protein?
Protein Abitram, Actin-binding transcription modulator, Protein Simiate.
What is the protein family that this protein belongs to?
Belongs to the ABITRAM family.
What are the subcellular locations of this protein?
Nucleus speckle. Cell projection, lamellipodium. Nucleus. Cell projection, growth cone. Cell projection, dendrite. Note=Localizes to somata and dendrites in cortical neurons.
Protein: CLPX_STRPG
Sequence: MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIRILTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGKSKPVLETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: BIOB_BUCAP
Sequence: MKRKWNLEDTKKLFSKPFFDLIFEAQKKHREYFNPNRIQISTLLSIKTGACPEDCKYCPQSSRYKTGLKKEPLLEIEQILKAAKKAKSSGSTRFCMGAAWKNPKEKDMPYLEKIVKEVKKMGMETCMTLGTLNNSQAKKLAKAGLDFYNHNLDTSSNFYSSIITTRTYEERLSTLKKVRNSGMKICSGGIIGLGEKKQDRMELLMELSNLSIQPESVPINMLVKIPGTPMEKNENVDPFEFIRVIAATRIMMPKSYIRLSAGRENMSDETQAMCFMAGANSIFYGCKLLTSSNPKEEKDQKLFEKLDLFPDYKIQSITEENKNNENLKISDVNKAQYYNAAI
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: EFTS_BURM9
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEADGDMAKAEELLRVKLGNKASKAASRVTAEGVVASFVGANAGALVELNCETDFVAKNDDFNAFAKTVAELVATQNPADVAALSALPLDGKTVDEVRLALVGKIGENISIRRFVRFETSNKLATYLHGSRIGVIVEYTGAQEQVGKDVAMHVAAMKPVSLSADEVPADLIEKERRVAEQKAAESGKPAEIVAKMVDGSVQKFLKEVSLLNQPFVKNDKQTIEQMLKAADAAVQKFALFVVGEGIEKRQDDFAAEVAAQVAAAKQQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_CAUVC
Sequence: MKQDIHPDYHFITVTLTDGSSYKTRSTYGKEGANLALDIDPRTHPAWTGGNAQLMDRGGRVSRFNAKFAGFTGKKA
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL6_ACICJ
Sequence: MSRVGKYPVALPQGVSITVVDGILTAKGKLGELKMPLSERVETVVEDGKVTVSPRDKEAASRMMWGTTRANVANMVQGVSQGYAKTLEINGTGFRAAVQGSNLVMNLGFSHDVVYPVPQGIKITCEKPTSIKVEGIDKRLVGQVCAELRAFRPPEPYKGKGVKFEGEAIRRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HEM6_METFK
Sequence: MNPTAIFDYLQGLQTRIVEAIELVDGKRFLHDSWQRAEGGGGTSCMLEEGNVFERAGIGFSHVIGNKLPPSASVAHPEAAGRSWQAMGVSLVFHPRNPYVPTVHMNVRFFVAEKPGEEPIWWFGGGMDLTPYYGFEEDAVHFHRTCRDAVAPFGEQYYPRFKKECDDYFYLKHRKEARGIGGIFFDDFNELGFEQSFAFQRSVGDAFINAYLPIVQRRKDIPYSERERDFQAYRRGRYVEFNLIYDRGTIFGLQSNGRTESILLSMPPIVKWRYDWKPEAGSPEARLYSDFITGRDWLTEHK
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX_I07A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVEPEDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPKEAKKQLKKGLKSQGQCAGSLIKAFRRTSPALRILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: RL10_METMA
Sequence: MAEERHHTEHIPQWKKDEIENIKELIQSHKVFGMVRIEGILATKIQKIRRDLKDVAVLKVSRNTLTERALNQLGESIPEMTRYLDNQTALIFTNESPFKLYKLLEQTKTPSPIKAGAIAPEDIIVQKGPTSFPPGPILGELQSAGIPASIDAGKVAVKETKVVCKAGEAVPQKLATMLSKLEIYPLIVGLDLRAAYDDGTIYEPELLAVDESKYFSDIIRAAQNAFNLSVNTAYPTGATIGTLLAKAYAESKSLGVNAVILEPGVMDSLLAKAHVQMTSVASEAAEKDANAVDDDLREVLGAAASAAAAATVAAPAAEEEKKEEEPEEEEEDHAEEDGMAGLGALFG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.