PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_STRSV
Sequence: MATIKEIQQRLELVTDLADPFLAEAANDQRSGVQKAIEKRKRAIQAELDEDLRLEQMLRYEKELYKADYQAIAGIDEVGRGPLAGPVVAAAVILPPECKIKGLNDSKKIPKKKHQEIYQAVLDKALAVGVGLMNNEIIDQVNIYEATKLAMKEALSKLSLKPDYLLIDAMKLDVDIPQESIIKGDANSLSIAAASIVAKVTRDKLMADYDKKFPGYDFAKNAGYGTRSHLQGLERSGVTPIHRKTFEPIKSMYE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_STRCA
Sequence: VLSGTDKTNVKGIFSKISSHAEEYGAETLERMFITYPQTKTYFPHFDLHHGSAQIKAHGKKVANALIEAVNHIDDISGALSKLSDLHAQKLRVDPVNFKLLGQCFLVVVAIHHPSALTPEVHASLDKFLCAVGAVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL31_SULTO
Sequence: MKEKDNFEMVINFKRAFMGRRNQRTKRAIKMIRNIVQRHFGAEKVIIDPLLAKSITYNGRDKIVRKVRVAVKKIGEKTYLVRLALKSE
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: Y1353_STAAR
Sequence: MATWLAIIFIVAALILGLIGGFLLARKYMMDYLKKNPPINEEMLRMMMMQMGQKPSQKKINQMMTMMNKNMDQNMKSAKK
What are the official names of this protein?
UPF0154 protein SAR1353.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CYB_ELIMI
Sequence: MTNIRKSHPLLKIINHSFIDLPTPSNISSWWNFGSLLGICLILQIATGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGMYYGSYMSMETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIVALVMVHLLFLHETGSNNPSGLNSDADKIPFHPYYTIKDILGILLLFLFLISLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLALLPHLHTSKLQSLMFRPLTQTLYWILVADLLTLTWIGGQPVEYPFVIIGQLASVLYFAIILIFMPMAGMIEDNMLKMD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CUL5_PONAB
Sequence: MATSNLLKNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLAIYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA
What is the function of this protein?
Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.  The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component.  ECS(SOCS1) seems to direct ubiquitination of JAK2.  ECS(KLHDC1) complex is part of the DesCEND (destruction via C-end degrons) pathway and mediates ubiquitination and degradation of truncated SELENOS selenoprotein produced by failed UGA/Sec decoding, which ends with a glycine.  As part of a multisubunit complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A.  May form a cell surface vasopressin receptor.
What are the official names of this protein?
Cullin-5, CUL-5.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: RLMM_KLEP3
Sequence: MNKVVLYCRPGFEKECAAEITDKAARLEVFGFARVKEDSGYVIFEGYQQDDGEKLVRDLPFSSLIFARQMFVVGELLRDLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELMKFCRKFTVPLRAALREAGVLTNYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWDERLANGMYAVDLGACPGGWTYQLVKRNMWVSSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSQNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRLWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_CALMQ
Sequence: MCIFVDVEGIDGVGKSTVIRLTADELRRRGYLVYTTSEPSDSPIGLFIRRSILESNLEVEPMALALLFAADRVIHYNRVIKPKVKEGYIVITERYIESSVAYQGSQGVPVEWIIEVNSMVAEPDLVIVLNAPLNTVASRLSNRGMLEYFERNTDFLRSVQEVYLRRARERNYPVIDASRVINNVVNDVLTLIEDKAKGKCKNYNQ
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: B2S22_SYLSP
Sequence: MFTMKKSLLFLFFLGTISLSFCEEERGADEDDGGEMTEEEKRGVLDTLKNVAIGVAKGAGTGVLKALLCQLDKSC
What is the function of this protein?
Antimicrobial peptide.  Active against some Gram-negative and a variety of Gram-positive bacterial strains.  Active against fungus C. glabrata 090902 but not against C. albicans ATCC 10231.  Shows hemolytic activity against human erythrocytes.
What are the official names of this protein?
Brevinin-2SN2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TM262_HUMAN
Sequence: MWLQDRIATFFFPKGMMLTTAALMLFFLHLGIFIRDVHNFCITYHYDHMSFHYTVVLMFSQVISICWAAMGSLYAEMTENKYVCFSALTILMLNGAMFFNRLSLEFLAIEYREEHH
What is the function of this protein?
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation.
What are the official names of this protein?
Cation channel sperm-associated auxiliary subunit TMEM262, Cation channel sperm-associated auxiliary subunit eta, Transmembrane protein 262.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
Protein: SECA2_MYCS2
Sequence: MPKTSSAKPGRLSSKFWKLLGASTERNQARSLSEVKGAADFEKKAADLDDEQLTKAAKLLKLEDLAGASDITQFLAIAREAAERTTGLRPFDVQLLAALRMLAGDVVEMATGEGKTLAGAIAAAGYALGGRRVHVITINDYLARRDAEWMGPLLKALGLTVGWITADSTADERREAYQCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTSHREQPRVEIIRMVGELEAGKHYDTDAESRNVHLTEAGARVMEAKLGGIDLYSEEHVGTTLTEINVALHAHVLLQRDVHYIVRDDAVHLINASRGRIASLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYPRVCGMTGTALAAGEQLRQFYKLGVSPIPPNTPNIRKDEPDRVYITAAAKIDAIVEHIAEVHKTGQPVLVGTHDVAESEELHEKLLKAGVPAVVLNAKNDAEEAAVIAEAGKLGAVTVSTQMAGRGTDIRLGGSDVGDDDAEKKKVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVVAAHLERSKLPMETDPDAGDGRIIAPRAASLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVERRETLLRTDTAREELKERSPERYAKLAEELGEDAEERLEKICRLIMLYHLDRGWCEHLAFLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEAAQQTFETAESVADEPGVDLSKLARPTSTWTYMVHDNPLADDTMSALSLPGVFR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: G6PI_RHILO
Sequence: MDKSAFQKQLAALRDHRSAAPASMRQAFAADPQRFQAFTATDGDLLLDWSKCAVDATTMDLLEKLAAAADLEGRRAAMFAGKKINITEDRAVLHTALRNLSGTGVTVDGQDVKADVLSVLDAMGAFADAIRSGKALGATGKKITDIVNIGIGGSDLGPAMATLALAPYHDGPRAHYVSNIDGAHIHDTLKGLSAETTLFIVASKTFTTVETMTNAQTARDWVQKALGKQAVGKHFAAVSTALDLVAKFGIEADRVFGFWDWVGGRYSVWGAIGLPVMIAVGPRNFRAFLDGAHEMDQHFRTAPLAGNLPALLGLVGWWHRVICGYPARAVIPYDQRLSRLPAYLQQLDMESNGKGVTLDGTPVATPTGPLVWGEPGTNGQHAFFQLLHQGTDFIPVEFLAAAVGHEPELKHQHDLLLANCLAQSEALMKGRTLDEARAQMLAKGMKPADVDKIAPHRVFSGNRPSLTILYRKLDPRTFGRLIALYEHRVFVEGTLFNINSFDQWGVELGKELATGLLPVVEGKESAANRDASTRGLVERIHQLRGSE
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STKLB_ARATH
Sequence: MNKKLLNPLEDPPTASSSEDVDEEISSGEDEKEHISNSSSSEEENELKDLSTQTLNSPSTEAPTLDSGSETNSDSDKPIVLTSQKKKEGTDSSGTKRASEGTSSKDIKRAKKVSGDDDNKKFQSLWTKEDEISLLQGMIDFKAETGTSAHDDMNGFFDIAKRYISFDVSKIQFGDKIRGLKKKYFGVRKKKGLDLDHDKKCLGLAKSIWGLDGKEVVVLGGDSETSNWFEKSFLVRVVARLGVDECIVKWKWSKVSKETKKRIEEKMKMVEAKELELLSQKIDVLKEVASVIAETI
What are the official names of this protein?
Probable transcription factor At1g44810, Storekeeper-like protein At1g44810.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
Protein: RS7_STRTD
Sequence: MSRKNRAPKREVLADPLYNSKIVTRLINRVMLDGKRGTAATIVYDAFEQIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRITLGLRWLVNASRARGEHTMKERLAKEIMDAANNTGAAVKKREDTHKMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: DER_PELPD
Sequence: MKPLVALVGRPNVGKSTLFNRLLGHRRAIVDDTPGVTRDRNYALINRFEKPFILIDTGGFEPVTEDRLLQQMREQSSLAMEEADVIIFMMDARSGLTPADVEVANMLRRVKKPVMYVVNKVDGEKLENDSAEFYSLGVENLYTISAEHNRGVYDLMDDLLELLPLDSGPESGEEITRIAVVGRPNVGKSSLVNRLLGFERVVANPTAGTTRDSVDTLFMCNKKPYLLIDTAGIRRKGKTTEKLEKYSVVDALRSIERADVVLVVLDATQGVTEQDERIAGYVHEAGRACVFVLNKWDAIEKDNSTFGLYVDKVRTGFKYLAYAPIVFVSAMTGQRTAKVMESVDEVMEQFSRRVTTSDLNRVFSEATSSHHAPLAHGRRVKFYFATQVTTRPPCFVVFTNQPDSIHFSYERYLINQFREAFGFNGTPLRIIFRGREKNSPSRRPVKDS
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CHT5B_MEDTR
Sequence: MANILNLKHLLTLALILLALATKSSTSSSSSITRVKGIYWLENPFFPPTTVDTSLFTHIFYSFLTPNNITYKLEISSSQILSLNTFTKTFKTKSPPAATLFSIGGAGSNSSLLAFIASDPPACAAFINSTIDVARTFGFDGIDLDWEFPKNTKEMNDLGEMLFQWRKAISDEGATTGRPPLLLTAAVYFAVNFSIYGEPRMYPVNSINENLDWVNVMSYELRGPRSNKTGAPSGTFDPKSNVSVVSGLLSWIHSGVVPEKLVMGMPLYGKSWKLRDPNVHGIGAPSVGSGPGVNGLMAYFQVLDFNRQKSAKVEYDVDTASVYSYSGSTWIGYDNPFTVSIKVGFAQALKLRGYFFWVAGLDTLDWKIATQASKAWKLV
What is the function of this protein?
Possesses chitinase activity in vitro toward glycol chitin, carboxymethyl-chitin, colloidal chitin, and the chitin oligosaccharides (N-acetylglucosamine) (GlcNAc)6 and (GlcNAc)5 (PubMed:27383628).  Hydrolyzes (GlcNAc)6 into (GlcNAc)4 and (GlcNAc)2, or two (GlcNAc)3 molecules (PubMed:27383628).  Has the capacity to reduce hyphal growth of the fungus Trichoderma viride in an agar-plate bioassay (PubMed:27383628).
What are the official names of this protein?
Class V chitinase CHIT5b, MtCHIT5b.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
Protein: RS9_ANOFW
Sequence: MAQVQYYGTGRRKSSVARVRLVPGEGRIIVNGRDIRDYVPYESLVEVVKQPLVLTETFGSYDVLVNVSGGGFTGQAGAIRHGIARALLQVDPEYRQTLKRAGLLTRDSRVKERKKYGLKGARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RL7_BRASO
Sequence: MADLQKIVDDLSSLTVLEAAELAKLLEEKWGVSAAAAVAVAAPGGGGAAAAPAEEKTEFTVVLASAGDKKIEVIKEVRAITGLGLKEAKDLVEGAPKPVKEGVNKEEAEKIKGQLEKAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PA56D_DAMDA
Sequence: SLRKMHALGET
What are the official names of this protein?
Pregnancy-associated glycoprotein 56D, FdPAG56D.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: PG074_VACCW
Sequence: MFMYPEFARKALSKLISKKLNIEKVSSKHQLVLLDYGLHGLLPKSLYLEAINSDILNVRFFPPEIINVTDIVKALQNSCRVDEYLKSVSLYHKNSLMVSGPNVVKLMIEYNLLTHSDLEWLINENVVKATYLLKINAYMINFKIDLTVDEIIDLVKDIPVGATLHLYNILNNIDLDIVLRISDEYNIPPVHDILSKLTDEEMCIKLVTKYPMDNVINFINQDVRYSPTFIKTIKDFVNEHLPTMYDGLNDYLHSVIIDEDLIEEYKIKSVAMFNLEYKTDVNTLTLDEQIFVEVNISYYDFRYRQFADEFRDYIMIKERRQITMQSGDRIRRFRRPMSLRSTIIKKDTDSLEDILAHIDNARKNSKVSIEDVERIISSFRLNPCVVRRTMLSDIDIKTKIMVLKIVKDWKSCALTLSAIKGIMVTDTINTVLSKILHHHRNVFKYLTSVENKEIAVCNCSRCLSLFYRELKSVRCDLHTDDGLLDRLYDLTRYALHGKINQNLIGQRCWGPLTEMLFNENKKKKLNNLMEYIKISDMLVYGHSIEKTLIPITDSLSFKLSVDTMSVLNDQYAKVVIFFNTIIEYIIATIYYRLTVLNNYTNVKHFVSKVLHTVMEACGVLFSYIKVNDKIEHELEEMVDKGTVPSYLYHLSINVISIILDDINGTR
What are the official names of this protein?
Protein OPG074, Protein O1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG074 family.
Protein: OTC_WOLSU
Sequence: MRHFLTLKDFSAQEILEILALSKEIKDDLKKGIRPPLMQGKVLGMIFEKSSTRTRVSFESGIYQLGGMGMFLSNRDIQLGRGEPMKDTARVISRMVDMVMIRTSGHERIEEFAKYSQVPVVNGLTDSYHPVQLMADYLTMMEQGKDQNPIVAYVGDGNNMTHSWLMLASKLGFELRVATPRGYEPNLKIFEEAQKIASLSGAKITLTNDPKRAVEGADVVTTDTWASMGQEEEKEKRARDFQGYCVDSALMGLAKSDAIFLHCLPAYRGQEVSEEVLEGPQSLIFDEAENRLHVQKGIMVWLDRKRS
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_RHOOB
Sequence: MRIVFAGTPEPAVPSLERLIRSPRHDVVAVITRPDAVAGRGRKVVRSPIGALADSHGIEVLTPERPTEPEFLARLTDLAPDCAPVVAYGALLPQKVLDIPAHGWVNLHFSLLPAWRGAAPVQAAIGAGDDMTGASAFRLEAGMDTGPVYGVVTERIRDTDTAGDLLGRLADSGAALLESVLDGIEDGAITAVPQPAEGVSHAAKVTVEAARIRWDRPAAVVDRHVRSVTPGPGAWTTIGDVRLKVGPVTPTDERLEPGEISVTKSGFLIGTSTAAVRLDRVQPQGKKQMAALDWARGARLDAEVRAQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SYP_NEIMA
Sequence: MKASQFFISTLKEAPAEAALASHKLMIRAGLIKANASGLYTWMPMGLRVLRKVENVVREEMARAGSVELLMPVVQPAELWQESGRWEFYGKELLRLKDRHDRDFCMGPTCEEVIADIVRKEINSYKQLPKNFYHIQTKFRDEVRPRFGVMRAREFVMKDAYSFHADYASLQTTYDAMYDAYCRIFTRLGLEFRPVAADTGSIGGTGSHEFQVLAESGEDVIAYSDTSDYAANVELAPTLPLKGERTAAQAELVKVHTPNVKTIESLVEFLNIPVEQTLKSIVVEGENEGEIVLLLLRGDHEFNDIKAEKLAGVKSPLTMASPAAIVEQFGANGGSLGPVGFAGKVYADFATEKGADWVIGANEDGYHYTGFNFGRDAAEPEFVDLRNVVEGDESPDGQGRLKLARGIEVGHVFQLRDKYTQAMNVSFLDNNGKSQIMEMGCYGIGITRVVAAAIEQNNDEKGIIWTKAMASFEVVIVPMNYKKSDTVREAADKIYAELLAAGADVLLDDRDERAGVLLNDSELLGIPHRIVIGDRALKEGNVEYAERRDNEAQAIAIGEIVARVTASLNA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCC1_STAAW
Sequence: MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
What are the official names of this protein?
Carbamate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOL2_ARATH
Sequence: MDKLKIAEWGEKLKTGGAQMSRMVSEKVKDMLQAPTLESKMVDEATLETLEEPNWGMNMRICAQINNDEFNGTEIVRAIKRKISGKSPVSQRLSLELLEACAMNCEKVFSEVASEKVLDEMVWLIKNGEADSENRKRAFQLIRAWGQSQDLTYLPVFHQTYMSLEGENGLHARGEENSMPGQSSLESLMQRPVPVPPPGSYPVPNQEQALGDDDGLDYNFGNLSIKDKKEQIEITRNSLELLSSMLNTEGKPNHTEDDLTVSLMEKCKQSQPLIQMIIESTTDDEGVLFEALHLNDELQQVLSSYKKPDETEKKASIVEQESSGSKDTGPKPTEQEEQEPVKKTGADDDKKHSEASGSSNKTVKEEKQAVKIELGLSSDEDEK
What is the function of this protein?
Binds ubiquitin in vitro (PubMed:24316203).  Might contribute to the loading of the ESCRT machinery (Probable).
What are the official names of this protein?
TOM1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TOM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: IF1_GEOMG
Sequence: MSKEEAIEVEGTVIEPLPNAMFRVELENGHVVLAHISGKMRKYFIKILPGDKVTVELSPYDLSRGRITYRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APE2_ARATH
Sequence: MKIVTYNVNGLRQRVSQFDSLLKLLDSFDADIICFQETKLRRQELTADLAIADGYESFFSCTRTSEKGRTGYSGVATFCRVKSASSSCETALPVTAEEGITGLVNSNSRGGKSETSTVAEGLEEYEKEELLMIDQEGRCVITDHGHFVVFNVYGPRAVADDADRIEFKHRFYGVLERRWECLLRQGRRVFVVGDLNIAPFAMDRCEAGPDFEKNEFRKWFRSLLVERGGSFSDVFRSKHPERKDAFTCWSSSSGAEQFNYGSRIDHILVAGSCLHQDEDKQGHSFLACHVKECDILTEYKRFKNENMPTRWKGGLVTKFKGSDHVPVFISFDDLPDIPEHSTPPLASRYLPMIYGFQQTLVSVFKKRRANEEAKAIEVSCSSSTQSNTSSICGDISTGPLRNCGSMGISLEKSCSFENKSTSGVTEAETVAATGSIDNLSDGIRASSVRALNISRDGDRKKARKIQSSQLSLKSFFTTNSKVNNVEDSSSSYVSSSPSSQVESITEPNVSGKEDSEPTTSTQEQDQTGSSAKQKNDAALMEWQRIQNLMQNSIPLCKGHKEACVARVVKKPGPTFGRRFYVCSRAEKQTVVISNGLHQNSETSKRVMRSK
What is the function of this protein?
Exhibits apurinic/apyrimidinic (AP) endonuclease activity in vitro (PubMed:25569774).  By contrast, another report show that APE2 has no biochemical activity (PubMed:25228464).  Unable to catalyze the conversion of 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) to 3'-OH (PubMed:25228464, PubMed:25569774).  Has no in vitro 3'-phosphatase activity (PubMed:25228464, PubMed:25569774).  Redundant with APE1L and at least one functional allele is required for seed viability (PubMed:19172180).  Has a strong non-specific affinity to DNA (PubMed:25228464).
What are the official names of this protein?
DNA-(apurinic or apyrimidinic site) endonuclease 2, Apurinic-apyrimidinic endonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the DNA repair enzymes AP/exoA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU4M_PORNA
Sequence: PIAGSMVLAAILLKLGGYGIIRMMQILPMTKTDVFLPFIILALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIMIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGFHNILPMTSTWWLLANLMNMATPPTLNFTSELLIMSTLFNWCPTTIILLGLSMLITASYSLHMFLSTQMGPTLLNNQTEPTHSREHLLMALHLVPLMMISMKPELII
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: DADA_SHIDS
Sequence: MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLVVRLDGTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKFRFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIAQEDGAPVSTILDETYKIAITRFDNRMRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.