PharMolix/UniProtQA huggingface dataset:
Protein: SRY_ARCGZ
Sequence: MFGVLNSDDHRAAIQQRNILAFGRTSSELWTSNPTSNYWCETRGNGRDSGQNRVRRPMNAFMVWSRDQRRKVALENPQMQNSEISKQLGYQWKMLTEAEKWPFFEEAQRLQAVHREKYPDYKYRPRRKALPQKSDKLLPAASSSLLCRQVLVDKWYPFTYRDSCSRATHSHMEDQLSSSKPVNIANSLLQREHHYSSTSLRGSPETLATHLSADPPFYPK
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: PROB_VIBVY
Sequence: MTTNQQSVAASQPKTIVVKLGTSVLTGGTLALDRAHMVELARQCAELKKQGHSVVVVSSGAIAAGREHLGYPALPNAMASKQLLAAVGQSQLIQTWESLFALYGIKIGQMLLTRADLEDRERFLNARDTINALVDNGIIPVVNENDAVATSEIKVGDNDNLSALVGILCGADKLLLLTDQKGLYTADPRKDPNAELIKEVKVIDDTLRKIAGGSGTTLGTGGMATKLQAADIARRAGIEVIIAAGRGQNVIFDALSPAPQGTRFLPCEEALENRKRWILAGPAASGDIVIDQGAVKAVVEKGSSLLAKGVTKVLGEFSRGEVVRVTDAQGHLVARGIASYSNQDMAKIAGKHSKDIISILGYDYGSEVIHRDDMVVIQE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_ACIAD
Sequence: MQTKGCRFFMNTEQLQKTLRSSQYAEQVLGLHQLYLEQDYQIDQFAAPLSRENIFQSVENELKDIQDESQWMRVVRILRARLMFRWIWQDANRLTNVVSLTRELSDFADACICAAKQFARAPLVAKHGEPVGYDGQIQDLIVIGMGKLGAQELNLSSDIDLIFAYDEQGETNGRKSIDVQQFCILWGQKLIYLLDHITADGFVFRVDMRLRPWGDGSALAISHMALEKYLIQHGREWERYAWIKARIISGGKHGDDLLEMTRPFVFRRYVDYSAFAAMREMKSMIEREVARRNIADDIKLGAGGIREVEFIVQVFQLIYGGSKRELQDRQCLVSLNHLGQAGLLQSQDVIELEDAYLFLRRVEHAIQALNDQQTQMLPMEPELRQRILDTLEYPTWDNFIEALNEKRHKVSEQFKKLIQEEVTSPDETDTELEQQLNAILDETAQNLVHEFWQSNALKRLPSKAVQRLKDFWPHFIEAILQSEHPQMAFMRLMPLIESVMRRTVYLVMLMESRGAMQRLVKMATVSPWICEELTQYPVLLDEFLSMDFELPQRKDLEDSLRQQLLRIEIDQVEDQMRVLRLFKKSNVLTVAASDVLAESPLMKVSDALTDIAEVSVAATLNLAYQAVVKKHGYPKDASGERCSLEHTGFAVIGYGKLGGIELGYGSDLDLVFIHYFDEQAETDGSKSITGFEFAMRVAQKFLSLMTTQTLDGRVYEIDTRLRPSGEAGLLVTSLKAFEQYQLKSAWLWEHQALVRARSIAGEAQLRQKFESLRCQILTQSRDENEVRDEVLKMRQKMKDHLGSSNEQKKHGIFHLKQDAGGIVDIEFMAQYMVLAWSGANPDLAHFSDNVRILEDAAQAGCLSSEDATALMHAYLRERAESHRLALANQSMQVNAAQWRHTREVVCKLWQRLIDPASTMALESE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: RS4_METVS
Sequence: MGDPRRLGKKYDTPNHPWIGERIQKEREISHKYGLVNKKELWKMETQLRNYRRQARKLISDTTTQGGKEAVQLFNVLKRYAILVEQEPTLDHILSLNIESILERRLQTLVYRKGLAKTAKQARQLIVHGHIAVNGRRVTSPSYLVSVSENNAIGYVPNSPMALENHPERTTAVSEENQ
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DNAK_HELPS
Sequence: MGKVIGIDLGTTNSAMAVYEGNEAKIIANKEGKNTTPSIVAFTDKGEILVGESAKRQAVTNPEKTIYSIKRIMGLMFNEDKAKEAEKRLPYKIVDRNGACAIEISGKVYTPQEISAKILMKLKEDAESYLGESVTEAVITVPAYFNDSQRKATKEAGTIAGLNVLRIINEPTSAALAYGLDKKESEKIMVYDLGGGTFDVTVLETGDNVVEVLATGGDAFLGGDDFDNRVIDFLASEFKSETGIEIKNDVMALQRLKEAAENAKKELSSAMETEINLPFITADATGPKHLVKKLTRAKFESLTEDLVEETISKIESVIKDAGLTKNEISEVVMVGGSTRIPKVQERVKAFINKDLNKSVNPDEVVAVGASIQGGVLKGDVKDVLLLDVTPLSLGIETLGGVMTKVIDRGTTIPAKKSQVFSTAEDNQPAVSIMVLQGERELARDNKSLGKFDLQGIAPAPRGVPQIEVTFDIDANGILTVSAQDKNTGKSQEIKISGSSGLSDSEIEKMVKDAELHKEEDARKKEVIEARNHADSLAHQTQKSLDEHKTNLNENDANEIQNAINALKECVKNDNATKAELEDKTKLLAQAAQKLGEAMANKNNAEQPKKKDDDVIDAEVE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: QUEA_RHIL3
Sequence: MRVDLFDFDLPDERIALRPAEPRDSARLLVIDPNAENSLSDHRVGDLTSFLRAGDALVFNDTKVIPAQLEGIRHRDGAGGQQVSATLHMRTSPSRWKAFAKPGKRIKQGDRISFGHSGESCFLGSLDATVEEKGEAGEVTLLFDLSGPALDEAIAAVGHIPLPPYIAAKRPEDERDRADYQTIYAREEGAVAAPTAGLHFTPGLFEALDRAGIERHFVTLHVGAGTFLPVKADDTADHKMHLESGYVSAEIAARLNAVRERGGRIVCVGTTSLRLIESAAEESGEIMPWAGATGIFITPGYRFKAVDMLMTNFHLPRSTLFMLVSAFAGFETMHAAYKHAISTGYRFYSYGDASLLFRKDR
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3CG_CONRE
Sequence: KCCMRPICMCPCC
What are the official names of this protein?
Conotoxin Reg12g.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GMDS_DICDI
Sequence: MSEERKVALITGITGQDGSYLTEFLISKGYYVHGIIQKIFHHFNTIVKNIYIKIDMLKEKESLTLHYGDLTDASNLHSIVSKVNPTEIYNLGAQSHVKVSFDMSEYTGDVDGLGCLRLLDAIRSCGMEKKVKYYQASTSELYGKVQEIPQSETTPFYPRSPYAVAKQYAYWIVVNYREAYDMYACNGILFNHESPRRGPTFVTRKITRFVAGIACGRDEILYLGNINAKRDWGHARDYVEAMWLMLQQEKPEDFVIATGETHSVREFVEKSFKEIDIIIKWRGEAEKEEGYCEKTGKVYVKIDEKYYRPTEVDLLLGNPNKAKKLLQWQIKTSFGELVKEMVAKDIEYIKNGDKYN
What is the function of this protein?
Participates in the synthesis of GDP-L-fucose, catalyzing the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose (GDP-4-dehydro-alpha-D-rhamnose) which is further catalyzed by GDP-L-fucose synthase (ger) (PubMed:19614564).  GDP-L-fucose is important for the synthesis of fucosylated N-glycans which are expressed on the cell surface (PubMed:19614564).
What are the official names of this protein?
GDP-mannose 4,6 dehydratase, GDP-D-mannose dehydratase, GMD.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
Protein: SRPE_CHLTH
Sequence: MSTVPVVQGAGSSNSAQDISTSSAPLTLKERISNLLSSTAFKVGLVVIGLLLVITALIFLVSAASFVNAIYLGIPAILGCVNICVGILSIEGHCSPERWILCKKVLKTSEDIIDDGQINNSNKVFTDERLNAMDGVVESLSRRNSLVDQTQ
What are the official names of this protein?
Sulfur-rich protein, serovar E, 15 kDa cysteine-rich outer membrane protein, Cysteine-rich protein A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Immunolocalizes to the inclusion membrane, the membrane that surrounds the intracellular parasite. This protein is recognized by CD8+ T-cells in both human and mouse infections, suggesting it gains access to the host cytoplasm.
Protein: GUAC_SHIDS
Sequence: MRIEEDLKLGFKEVLIRPKRSTLKSRSDVELERQFTFKHSGQSWSGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNNL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: MOBB_BPT4
Sequence: MNYLNIYNLLIEKGLNRGNDKSLLTYYTETHHIIPRCMGGTDDKTNLVLLTPEEHFTAHLLLFKIYRLPKLALAIRMMCYSSDGTRLNNKMYGWIKTAVSSSISESMKEFWKDDDNKKYMSNARRNAGKPIYQYDLNGNFIRKYRCITDAAEDMSYSCSTSIKQCVDGKRKTAGGFQWKYYYSDNIGKPSRMSNATKQKMSKSKRGITQKRNVPVFQYDTTGKLLRVFPRIKDAAVSVKGCMSNIKKCISGKSKIAYGYVWAYS
What are the official names of this protein?
Probable mobile endonuclease B.
What is the protein family that this protein belongs to?
To phage T4 mobC and mobD.
Protein: CYB_GOMVA
Sequence: GLCLASQLLTGLFLAMHYTSDIATAFSSVAHICRDVNYGWLIRNMHANGASFFFICIYLHIGRGLYYGSYLYKETWNIGVVLLLLVMMTAFVGYV
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YEGP_YERPE
Sequence: MALGHYEIKKAKNGQYHFNLKASNGEIILSSEMYASKASAENGIASVQSNSPQESQYELKHNTKNEPYFVLKAKNHQVIGVSESYSSPTAAKNGIASVMKNGLSTVIKDLTL
What are the official names of this protein?
UPF0339 protein YegP.
What is the protein family that this protein belongs to?
Belongs to the UPF0339 family. Duplicated subfamily.
Protein: SYA_CUPPJ
Sequence: MKVSDIRSKFLQFFESKGHTVVRSSSLVPANDPTLLFTNSGMVQFKDVFLGTDKRPYSRATSSQRSVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKREAIQYAWELLTKVYQLPAEKLWVTVYAEDDEAYDIWAKEVGVPTERIVRIGDNKGSRYASDNFWQMADTGPCGPCSEIFFDHGPDVWGGPPGSPEEDGDRYIEIWNLVFMQFNRDEQGNMTPLPKPCVDTGMGLERIAAVLQHVHSNYEIDLFQALIKAAARETHIDNLNQNSLKVIADHIRACSFLIVDGVIPGNEGRGYVLRRIVRRAIRHGYKLGQKTPFFHKLVADLVAQMGEAYPELADAQGRVTEVLKAEEERFFETIENGMSILDAALADLKLKGGKTLDGELAFKLHDTFGFPLDLTQDVCREQEIAVDEAAFDAAMNRQREQARAAGKFKMAAGLEYSGDKTVFHGYEKLELPQAKIIALYVDGAAVDAMQPGQTGVIVLDNTPFYAESGGQAGDQGVLKAGNAVFAVADTTKIQADVFGHQGTLEGGALKVGDTVQPQVDALRRARTVRNHSATHLMHKALREVLGTHVQQKGSLVDADKTRFDFSHNAPMTDEQIRRVEDIVNAEILRNEDTHAEIMPFDDAVKSGAMALFGEKYADDVRVLSIGTSKELCGGTHVHRTGDIGLFKIVVEGGVAAGIRRVEAITGDNALHYLQKLDAKLNEAAAALKAQPSELVPRIGQVQEQVRALEKELERLKSKLASSQGDELAEQAVDVKGLKVLAAQLEGADVKTLRETMDKLKDKLQSAAIVLAAVADGKVSLIAGVTADATGKVKAGELVNFVAQQVGGKGGGRPDMAQAGGTEPGKLPQALSGVVEWVSAKV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_POLSJ
Sequence: MRLILLGAPGAGKGTQATFICQKYGIPQISTGDMLRAAVKAGTPLGVEAKKIMDAGALVSDDLIINLVKERIAQPDCAKGFLFDGFPRTIPQADAMKAAGVKIDYVLEIDVPFEAIIERMSGRRSHTASGRTYHVKYNPPKVEGKDDVTGEPLIQREDDKEETVRKRLEVYSAQTRPLVEYYSSWAKTSPQAAPKYRAISGMGGVDEITERAFQALSS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R1B14_SOLDE
Sequence: MYFNNELSGLKDRFLKSLLAQKYPDRINFFLWELKFLDCFLHLQNFAFASECGMLDVSQKMLKNFKRMCATFRSIRPNAGSDNAFAYLKEVICKRLCATLLNTRPDACSDDGFAYWNEVIWKTKQEFRAKYSFPKTPLASNKVDDDDINIHSPKFVMEFIDAVVGNLNVLVKINDPCSLLFVPGPKEQIDQVSKELKLLRFFVCFVSNKCIEPQYGHTTFYIHALIEASHIAMVVWLHLPVYGNGNQDLAPSEVSRLLSDFISRNSNYIDVLKALKSTIPQAQNKHAAESGIVETPTHNLMVGLSDQMVNLQEMLCLLRDNLIHLPILDLEFHLQDMDSVILDAGLLIYSLYDIEGEKEDTVLDDMNRALGFDLPRNIEPIKVMVYLVMQKAFQCNLPRVHGLGYVDFLLKNLNDFQGRYSDSLAFLKNQLQVIQTEFESLQPFLKVVIEEPHNKLKTLNEDCATQIIRKAYEVEYVVDACINKVAPHWCLERWLLDIIEEITCIKAKIQEKNTVEDTMKTVITHTSSQLARTPRMNEEIVGFKDVIENLRNRLLNGTKGQDVISIHGMPGLGKTTLANRLYSDRSVVSHFDICAQCCVSQVYSYKELLLALLCDAVGDDSARRKHNENKLADKLRKTLLSRRYLILVDDVWDNSAWDDLRGCFPDANNRSRIILTTRHHEVAKYASVHSDPLHLRMFDEDESWKLLEKKVFGEKRCSSLLLKDVGLRIAKMCGQLPLSIVLVAGILSEMEKEVECWEQVANNLGTHIHNDSRAIVNQSYHVLPCHLKSCFLYFGAFLEDEVIDISRLIRLWISESFIKSSEGRRLEDIAEGYLENLIGRNLVMVTQRADSDGKVKACRLHDVLLDFCKERAAEENFLLWINRDQISTKAVYSHKQHAHLAFTEMDNLVEWSASCSLVGSVLFKNPDSYLYSPAFSTSLILLNFKFLKVLDLEHQVVIDFIPTELFYLRYLSASIEQNSIPSSISNLWNLETLILKSTPVGRHNTLLLPSTIWDMVKLRHLHIPKFSPENEEALLENSARLYDLETISTPYFSSVEDAELILRKTPNLRKLICEVECLEYPPQYHVLNFPIRLEILKLYRSKAFKTIPFCISAPNLKYLKLSGFYLDSQYLSETVDHLKHLEVLKLCDLEFGDHREWKVSNGMFPQLKILKLEYLSLMKWIVADDAFPNLEQLVLHGCQDLMEIPSCFMDILSLKYIEVDMSNKSVVKSAKNIEETQVEDNQNTNFKLVIIKKMVLKFDIYQNHDKGRLETFKKLVPLPGVKSVRFDMDEKKVTVTGVMDANEVQLVVSKLRKRGML
What is the function of this protein?
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1.  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein.  That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
What are the official names of this protein?
Putative late blight resistance protein homolog R1B-14.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: JAZ1_SOYBN
Sequence: MSSFPNTVAEGRRSGKAPEKSTFSQTCSLLSQFLKEKRASADSTLGIGGKMEPKANTKALLGSLQNSDGALKLSASAMEFLPQLVENPCIKKSRSPGPESPQLTIFYAGKMLVFDAFPPEKATEVMEMATKLASNNSGTEESPPSLPVTTEKLAVSKMPQTNTSSETPKPGNQGVGSDMRYPRRASLLKFLEKRKERVNARGPYQMNNLKPEGSSSGGEPEDQCSKQFDLNF
What is the function of this protein?
Repressor of jasmonate responses.
What are the official names of this protein?
Jasmonate ZIM domain-containing protein 1, GmJAZ1, HopZ1a-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus. SUBCELLULAR LOCATION: Nucleus. Cell membrane. Note=(Microbial infection) Interacts with Pseudomonas syringae HopZ1a at the plasma membrane and in the nucleus.
Protein: HIS6_LACLM
Sequence: MLTKRIIPCLDIKNGKVVKGINFVGLKEIGDPVELAKIYEEQCADEIVFLDITASFEEREIIGELIGRAARELSIPLTVGGGIRSINDFRRILASGADKVSINSAAIENPEFIHQAANEFGVQCVVVAIDAKANESGSSFEVYIKGGRENAGIDLVEWAKKCEKLGAGEILLTSMDKDGTKTGYDLKMLNAVCSAVNIPVVASGGCGSISDIIDVFEKTKSDAALVASLFHYGEATVDEVKEELIKNRIPARIIKKEII
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODPB_ACHLA
Sequence: MAIITLLEAINQAIDQAMEKDESIVVFGEDAGFEGGVFRVTAGLQKKYGETRVFDTPIAESAIVGSAVGMAINGLKPIAEIQFDGFIFPGYTDLVTHAARMRNRSRGQFTVPMVLRLPHGGGIRALEHHSEALEVLFGSIPGLKVVTPSTPYDAKGLLLAAINDPDPVVFLEPKRIYRAGKQEVPAEMYEIPIGKAKVVKQGTDMTVVAWGSIVREVEKAVKLVEAEGISVEIIDLRTISPIDEETILNSVKKTGKFMVVTEAVKSYGPAAELITMVNEKAFFHLEAAPVRFTGFDITVPLARGEHYHFPQPEKIAAYIRKLAKARP
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
Protein: RS4_ALIF1
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIDNAPGVHGARRGRLSEYGVQLREKQKVRRMYGVLEKQFRNYYKDAARLKGNTGENLLQLLEGRLDNVVYRMGFGATRAESRQLVSHKSILVNGKVVNVPSFKVAANDVVSIREKAKQQSRIKAALEVAEQREKPTWIEVDAGKMEGTFKRLPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DXR_CAUVC
Sequence: MGALTSPRKVVVLGSTGSIGLSTLSLFEESGAPVQILALTAGRNVERLIEQARRWKPSLAVIEDESRLDDLRAGLAGTGVEAAAGADAVRDAAAMGADWVMSAIVGAAGLAPTVAAARTGAVIALANKESLVCAGPALLAIAKAAGGSVIPVDSEHSAIFQVLQSECAHRVSRLILTASGGPFRTWDKAAMARATPEQAIAHPNWSMGAKISVDSATMMNKGLEMIEASYLFATPEDRVDVVIHPQSVIHSLVEYVDGSTLAQLGPPDMRAPIACAFAWPDRLPWPAPRLDLAAYGQLTFESPDVERFPAIGIAREALRLGGGAPAAMNAANEVAVAAFLDRRIGFLDIAGAVAGTLERMNSLGDLSVAESDAVETAMLIDGSARRIAAEVVAQKRQRA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: G3P_KLEAE
Sequence: IVFRAAQKRSDIEIVGINDLLDAEYMAYMLKYDSTHGRFDGTVEVKDGHLVVNGKTIRVTAEKDPANLKWNEIGVDVVAEATGIFLTDETARKHITAGAKKVVLTGPSKDNTPMFVRGANFETYAGQDIVSNRSCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGAAQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAASYEEIKKAIKAASEGPMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLV
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_ALIF1
Sequence: MTQDEMKKAAGWAALEYVEAGSIVGVGTGSTVNHFIDALATMKNEIKGAVSSSVASTEKLKELGIEVFDCNDVAGLDVYVDGADEINGKNEMIKGGGAALTREKIVAAISDKFICIVDDTKQVDVLGQFPLPVEVIPMARSYVARELVKLGGDPAYREGVITDNGNVILDVHGMKITDAKDLEDKINALPGVVTVGLFAHRGADVLLVGAPEGVKKFD
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: GLMU_PSYWF
Sequence: MNNTLTTIILAAGKGTRMQSAKPKVLQILADKPLLAHVLDTCQSISVDKTIVVYGFGGDQVQQAMTDYSLTWVEQTEQLGTGHAVKVALDELPSTGKSLILYGDVPLVSAETLSRLKQANVQGMSMLTLTVDNPFGLGRIKRDEQGNITAIVEQKDASEQEQAIREINSGIYCVDNALLHQYLPNLSNDNAQQEYYLTDIVKMAVADGIAIAAIEPDYEFEIEGVNNRQQLAQLERKWQAKLVEDLQVQGVQFADPNRVDIRGEVSVGQDVFVDINVVFKGKVSLGNNVTIEAGCMIKDSQIGDNVHIKPYCVFDDAQVAQGATIGPFAHLRPQTVLEKNTRLGNFVEIKKSRIGEGSKVNHLSYVGDAQIGAGVNFGAGAITCNYDGVNKHQTIVGDNAFIGTNTSLVAPVTIGQTATIGAGSVITKNVEDNALAIGRGRQVQKDNYQRPEKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_TOXGO
Sequence: MAQVPASGKLLVDPRYSTNDQEESILQDIITRFPNVVLMKQTAQLRAMMTIIRDKETPKEEFVFYADRLIRLLIEEALNELPFEKKEVTTPLDVSYHGVSFYSKICGVSIVRAGESMESGLRAVCRGCRIGKILIQRDETTAEPKLIYEKLPADIRDRWVMLLDPMCATAGSVCKAIEVLLRLGVKEERIIFVNILAAPQGIERVFKEYPKVRMVTAAVDICLNSRYYIVPGIGDFGDRYFGTM
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UPRT, UPRTase, UMP pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: YLXG_BACSU
Sequence: MTSISSEYKLPEKTNTVSTNNSSLGKDEFLKILMTQVQNQDPLNPIDDKEFISQMATFSSLEQMMNLNTTMTQFVENQDPFTTYVDWMGKEVSWTDGKSATDKTGTVSSVKHFKGNYYLVLDDGTEISPANVMSVGQSSK
What are the official names of this protein?
FlaA locus uncharacterized protein YlxG, ORF 8.
What is the protein family that this protein belongs to?
Belongs to the FlgD family.
Protein: SSRP_PROMM
Sequence: MAKGGNKKATAAARAAANRLLADNRLARHQYEILDTLETGIELVGTEVKSIRAGQANLRDGFCLIRKGELQLHNVHISPHSHAGSYFNHDPLRTRKLLAHRREIDKLRGQLDRKGLTLIPLNLHLKGSWIKLTIGLGKGRKLHDKRQDEKRKQADREVKSALARY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.