PharMolix/UniProtQA huggingface dataset:
Protein: FAAA_RAT
Sequence: MSFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPVLSKHQHVFDETTLNSFMGLGQAAWKEARASLQNLLSASQAQLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSLQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMRPDNSKPPVYGASKRLDMELEMAFFVGPGNRFGEPIPISKAQEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVPNPKQDPKPLPYLCHSQPYTFDINLSVALKGEGMSQAATICRSNFKHMYWTILQQLTHHSVNGCNLRPGDLLASGTISGSDPESFGSMLELSWKGTKAIDVGQGQTRTFLLDGDEVIITGHCQGDGYRVGFGQCAGKVLPALSPA
What are the official names of this protein?
Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: BGL1_SACFI
Sequence: MLMIVQLLVFALGLAVAVPIQNYTQSPSQRDESSQWVSPHYYPTPQGGRLQDVWQEAYARAKAIVGQMTIVEKVNLTTGTGWQLDPCVGNTGSVPRFGIPNLCLQDGPLGVRFADFVTGYPSGLATGATFNKDLFLQRGQALGHEFNSKGVHIALGPAVGPLGVKARGGRNFEAFGSDPYLQGTAAAATIKGLQENNVMACVKHFIGNEQEKYRQPDDINPATNQTTKEAISANIPDRAMHALYLWPFADSVRAGVGSVMCSYNRVNNTYACENSYMMNHLLKEELGFQGFVVSDWGAQLSGVYSAISGLDMSMPGEVYGGWNTGTSFWGQNLTKAIYNETVPIERLDDMATRILAALYATNSFPTEDHLPNFSSWTTKEYGNKYYADNTTEIVKVNYNVDPSNDFTEDTALKVAEESIVLLKNENNTLPISPEKAKRLLLSGIAAGPDPIGYQCEDQSCTNGALFQGWGSGSVGSPKYQVTPFEEISYLARKNKMQFDYIRESYDLAQVTKVASDAHLSIVVVSAASGEGYITVDGNQGDRKNLTLWNNGDKLIETVAENCANTVVVVTSTGQINFEGFADHPNVTAIVWAGPLGDRSGTAIANILFGKANPSGHLPFTIAKTDDDYIPIETYSPSSGEPEDNHLVENDLLVDYRYFEEKNIEPRYAFGYGLSYNEYEVSNAKVSAAKKVDEELPEPATYLSEFSYQNAKDSKNPSDAFAPADLNRVNEYLYPYLDSNVTLKDGNYEYPDGYSTEQRTTPNQPGGGLGGNDALWEVAYNSTDKFVPQGNSTDKFVPQLYLKHPEDGKFETPIQLRGFEKVELSPGEKKTVDLRLLRRDLSVWDTTRQSWIVESGTYEALIGVAVNDIKTSVLFTI
What are the official names of this protein?
Beta-glucosidase 1, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
Protein: YKJ4_SCHPO
Sequence: MTAKMAEPLYFRIWSSLNIICLMVTFLNVQLSKTPIVLMPLFIALLKNNRKRETKKQTISVLVQKREEKTKLVLDDANNHNHAFLYHCQYLGQKKHVVIQ
What are the official names of this protein?
Uncharacterized protein C513.04.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: TYPH_LEGPH
Sequence: MHDSFLSANGGFVVSKKTPHGLRLKHLGIKTYHEAIIYMREDCHVCHSEGFEVQTRIQVTLGSRSIIATLNVVTSELLQPGEAGLSDYAWESLHAKEGDEIQVSHPKPLESLSYVHAKIYGNELSFEQMKVIIDDVLSGRLSDVQISAFLAASGAGRLTRTEVMKLTKAMIDSGDRLSWPSPLVVDKHCVGGLPGNRTTLIVVPIVASFGLMIPKTSSRAITSPAGTADTMETLAPVHLSPQKMRQVVEQENGCIVWGGAVSLSPADDVLIRVERAIDLDSEGQLVASILSKKIATGATHAVIDIPVGPTAKVRNQSMALLLKQSLEEVGNELGLVVRALFTDGSQPVGHGIGPSLEARDVLAVLQGLPDAPNDLRERALTLAGAALECSSKVPPGLGKSIATQLLESGQAFKKFQAICEAQGGMRELTKARFTYPVVAAKEGKVSLIDNRKLAKIAKLAGAPKSKSAGIDLHAHVGESVEQGEPLFTIHSESLGELHYACDLLRDKQDIIILGENP
What are the official names of this protein?
Putative thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: OMP2A_BRUSS
Sequence: MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTETCLRVHGYVRYDVKGGDDVYTGSDRKGWDKGARFALMFNTNSETELGTLGTYTQLRFNYTSNNSRHDGQYGDFSDDRDVADGGVSTGTDLQFAYITLGGFKVGIDESEFHTFTGYLGDVINDDVVAAGSYRTGKIAYTFTGGNGFSAVIALEQGGEDVDNDYTIDGYMPHVVGGLKYAGGWGSIAGAVAYDPVIEEWATKVRGDVNITDRFSVWLQGAYSSAATPNQNYGQWGGDWAVWGGAKFIATEKVTFNLQAAHDDWGKTAVTANVAYQLVPGFTITPEVSYTKFGGEWKDTVAEDNAWGGIVRFQRSF
What is the function of this protein?
Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
What are the official names of this protein?
Porin Omp2a.
What is the protein family that this protein belongs to?
Belongs to the alphaproteobacteria porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: MUTL_YERPY
Sequence: MPIQILPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGCGISKDDLALALARHATSKISSLEDLEAILSMGFRGEALASISSVSRLILTSRTAEQSEAWQAYAEGRDMAVTIKPAAHPVGSTLEVLDLFYNTPARRKFMRTEKTEFGHIDEVVRRIALARFDVAINLNHNGKLIRQYRAAPDPAQHERRLASICGPAFLQHALAIAWQHGDLNIHGWVADPAASHTLSEMQYCYVNNRMMRDRLINHAIRQAYQDRLNDAQQPAYVLYLDIDPHQVDVNVHPAKHEVRFHQARLVHDFIYQAVTAVLQQTNAPILNISEEGEVDAPRWQQENRVAAGTNKYAQPEAAKSSAAEQAVARERSSARERAAPAYKEDHPYQKQQGELYRQLLQPSAAAKPATSPAAIPASSVSSPSIPVQRITQAEEPLHGDNYSFGRVLTVFPPCYALIEYQGGVALLSLAVAERWLKQAQLSPPEEGLRPQPLLIPLKITLDKNEIAACQNHEKLLITMGIELSVEQGRATLRAVSLPLRQQNLQKLIPELLGYLSQHEEISPDTLATWLARHLGSEHEVWNVSQAIQLLTEVERLCPQLVQSPPAGLLQPIDIKAALATLTHE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: INS_TORMA
Sequence: LPSQHLCGSHLVEALYFVCGPKGFYYLPKAXXFVDSLAGYSKHQNGGISGIVEHCCHNTCSLFDLEGYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1102_STRPN
Sequence: MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SP_1102.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RAMAC_MOUSE
Sequence: MSDTSEEIPNFEEMFASRFTKDDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNWLQDNRQFRGRDNRRGWPSDNRSNQWHGRSWGNNNYPQQRPEPYYQQQYTQYGHNQRPPYGYY
What is the function of this protein?
Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs.  Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT.  Regulates RNMT expression by a post-transcriptional stabilizing mechanism.  Binds RNA.
What are the official names of this protein?
RNA guanine-N7 methyltransferase activating subunit, Protein FAM103A1, RNA guanine-7 methyltransferase activating subunit, RNMT-activating mRNA cap methylating subunit, RNMT-activating mRNA cap methyltransferase subunit, RNMT-activating mini protein, RAM.
What is the protein family that this protein belongs to?
Belongs to the RAM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DTDA_METS5
Sequence: MDVSVIISSKDPVGQTVKRLGYSFEEIDEDVTEFSYSKGDSIVMICRHESSTRTPAFTIHHPGNPGKSAMGGKPESLAIANARLLTSIFRSMTRIDANIEKIIEATHHGPTEIPKPITFVEIGSDPEMWNNEKLVGKLVEAVLKGIERMEETDCQNTTLIYGGPHYSKLASTVAQSDCISHIISKHYISELSSNVIVQSIERNITRPRTAVLDSIPRSKRETLTSILSSNNISIELR
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: EIF3E_ASPFC
Sequence: MAANVSPSAETLSSGAAAHPSNTAEEIANQYNLLPKLIPYLDRHLVFPLLEFSSGQDDEKEIVRAKYELLKHTNMTDYVANLWKEINNSDDIPDEFVKKREEVLAKLQQYEEESAKITQLLQDESVVANLRSDKVANLKFLEEQHGVTVEMVNSLYDYGRFQYSCGSYGNAAELLYQFRVLSTDNDKVASATWGKFASEILTTSWEAAMEEVQKVKDSIETRLFNNPLGQLQNRSWLIHWSLFPFFNHDPARDVLTDLFFSPAYINTIQTNCPWILRYLAAAVITNRNRAHKNSSVYQKQLKDLIRVVRQEGYEYNDPITDFIKALYVDFDFEEAQKKLGEAEEVLRSDFFLVSTTDAFVEAARHLISESYCKIHQRIDIKDLSTRLGLNQDEGEKWIVNLIRDTRVDAKIDYKEGTVIMNHPPQSVYQQVIEKTKGAFFRTQVLSAAVAK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_TRIV2
Sequence: MVQVELDVQDCFLESSPEAAQASGYIDSQVSSATWEDWFHRWLEILDSSLPPAPSYEIGLRLTDDTEIQAINAQYRQQNKPTDVLAFAALEADLPQNPEMVAEPLYLGDIVVSINTAQRQAGQQEHSLSTELAWLTAHGLLHLLGWDHPDEESLIAMLQQQVVLLDAVGIKININY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSHB_HUMAN
Sequence: MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV
What is the function of this protein?
Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner (PubMed:7646467, PubMed:9215686).  Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes (PubMed:10369661).  Participates in ophthalmate biosynthesis in hepatocytes (By similarity).
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic GSH synthase family.
Protein: RL19_FRATH
Sequence: MKNKFVELVEKSQLRNDLPEFNPGDSITVNLWIKEGDKQRIQAFKGFVLRKRNRGLHSAFTVRKMSSGMGVERTFQTHSPLIDSIIVEKRADVRRAKLYYMRGLTGKAARIKEKV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MMP24_HUMAN
Sequence: MPRSRGGRAAPGPPPPPPPPGQAPRWSRWRVPGRLLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAPFAGQNWLKSYGYLLPYDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
What is the function of this protein?
Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence.  Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia.  Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence.  May play a role in axonal growth.  Able to activate progelatinase A.  May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans.  Cleaves partially fibronectin, but not collagen type I, nor laminin (By similarity).
What are the official names of this protein?
Matrix metalloproteinase-24, MMP-24, Membrane-type matrix metalloproteinase 5, MT-MMP 5, MTMMP5, Membrane-type-5 matrix metalloproteinase, MT5-MMP, MT5MMP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
[Matrix metalloproteinase-24]: Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Recycled back to the plasma membrane through the trans-Golgi network via interaction with APBA3. SUBCELLULAR LOCATION: [Processed matrix metalloproteinase-24]: Secreted, extracellular space, extracellular matrix. Note=Also shed from cell surface as soluble proteinase, by a proteolytic cleavage.
Protein: PTR33_ARATH
Sequence: MVHVSSSHGAKDGSEEAYDYRGNPPDKSKTGGWLGAGLILGSELSERICVMGISMNLVTYLVGDLHISSAKSATIVTNFMGTLNLLGLLGGFLADAKLGRYKMVAISASVTALGVLLLTVATTISSMRPPICDDFRRLHHQCIEANGHQLALLYVALYTIALGGGGIKSNVSGFGSDQFDTSDPKEEKQMIFFFNRFYFSISVGSLFAVIALVYVQDNVGRGWGYGISAATMVVAAIVLLCGTKRYRFKKPKGSPFTTIWRVGFLAWKKRKESYPAHPSLLNGYDNTTVPHTEMLKCLDKAAISKNESSPSSKDFEEKDPWIVSTVTQVEEVKLVMKLVPIWATNILFWTIYSQMTTFTVEQATFMDRKLGSFTVPAGSYSAFLILTILLFTSLNERVFVPLTRRLTKKPQGITSLQRIGVGLVFSMAAMAVAAVIENARREAAVNNDKKISAFWLVPQYFLVGAGEAFAYVGQLEFFIREAPERMKSMSTGLFLSTISMGFFVSSLLVSLVDRVTDKSWLRSNLNKARLNYFYWLLVVLGALNFLIFIVFAMKHQYKADVITVVVTDDDSVEKEVTKKESSEFELKDIP
What is the function of this protein?
Low-affinity nitrate transporter.
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 6.4, AtNPF6.4, Nitrate transporter 1.3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y5909_MYXXD
Sequence: MAEMSYRTALVTGASSGLGRGLALWLARRGVRVFAAGRRLPQLQALRDEAQAAGVTVEPVELDVTKADATLERIRALDAEAGGLDLVVANAGVGGTTNAKRLPWERVRGIIDTNVTGAAATLSAVLPQMVERKRGHLVGVSSLAGFRGLAGHAAYSASKAFLSTFMESLRVDLRGTGVRVTCIYPGFVKSELTATNNFPMPFLMETHDAVELMGKGIVRGDAEVSFPWQLAVPTRMAKVLPNPLFDAAARRLR
What are the official names of this protein?
Uncharacterized oxidoreductase MXAN_5909.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RBD2_CANGA
Sequence: MIAPQRMLMPEGRPPAGLTTGLLIFLTFLFGISQLYEDFKNHFVLTPNSLFDIDLGKLSLYPLMHLSYLHLVFNALAIVGPLNNFESSHGTIHTGVVLNLSAVIAGIIYCVVSRLLSLETGVAGASGWVFTFITYLCVKESQLYPRLELSRFIPGVTQSIPTQFTPVVFLLFTAIVFFQSSFLGHTAGMIVGYIMGYGETWFNILIPPAWIIEKIEEKADPLINLIPFGIKFYRSTEINTDDGYRSFFPGQEVLPTTTPGNVLGTA
What is the function of this protein?
Probable serine protease.
What are the official names of this protein?
Rhomboid protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Protein: RS11_BDEBA
Sequence: MNTDKKAVTKKKVKRNVPQGNCYIQAGFGNVIVTMTDPTGATVSWSSAGHLGFKGSRKGTPFAAQVAAEDAAKKAMEAGMKSVDVYLKGPGAGREPAIRALAATGMRILSLKDVTPVPHNGCRPPKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DLTC_STRPD
Sequence: MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVELESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_XYLFT
Sequence: MIDTVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNPTQFGPHEDFQRYPRTPEADMRGLEHVGCDVLWLPSVETMYPLGTERTVRLFIPCVSDVLEGTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVIRQMVVDLAFPIEILGGCIVRESDGLAMSSRNQYLSMQQRPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQVDYAVIRLPDLCEPIDGIVISQGIALVAARLGNTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_PSYA2
Sequence: MSTSAPINRRLTKKIYVGDVAIGGDAPISVQSMTNTDTCDVAATVAQIERCVEAGADLMRVSTPTMDTVKAFGEIRKLVSVPLIADVHFDHKIALAVAAAGADCLRINPGNIGSDAKVREVVACAKHYNIPIRIGVNAGSLEKDIQRKYKEPNGAAMLESAMRHIDILERLNFDQYKVSVKASNVFLTMDAYRLISAQIDNPLHLGVTEAGVYRTGSVKSAIALGGLLLDGIGDTIRISLAAEPEEEIKIGFDILKSLNIRSNGVNFIACPSCSRQEFDVIRVMTALESRLEDIREPMNLSVIGCKVNGPGEAKEADIGIVGAAPKSLVYRMGEKSHLIDTDNLVDEIEGMVRAHAEELAKKRENEIIRVR
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PANB2_PSEE4
Sequence: MPEVTLTTLNGLKAKGEKITMLTCYDATFAKAASEAGVEVLLVGDSLGMVLQGHDSTLPVSNDDMAYHTASVKRGNNGALILTDLPFMAHATPELAFTNAAQLMRAGAHMVKIEGAAWLAETIRLLAERGVPVCAHMGLTPQTVNVLGGYKVQGRQEAQARQMRADAIALEQAGAAMLLLECVPSELAAEITQAVGIPVIGIGAGSATDGQVLVLHDMLGLSLSGRVPKFVKNFMAGQPDIQSALAAYVEAVKTVSFPASEHGFSA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 2, Ketopantoate hydroxymethyltransferase 2, KPHMT 2.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1423_HELPY
Sequence: MRIDKFLQSVGLVKRRVLATDMCNVGAVWLNGSCAKASKEVKAGDTISLHYLKGIEEYTILQIPALKNVPRKDTHLYIAPKTKE
What are the official names of this protein?
Uncharacterized protein HP_1423.
Protein: Y3672_STRCO
Sequence: MSVLYGIAAATVTATASFLLTAVLAALLRAPALRLAVVDRRRRRPVPLLGGVAVVLVTAVVAWAGDRAGVVPLGPAAGRLLAAATVVGALGLAADVWRLRRRWLLAGTAVAAACVVPYGETGPVAGALAVGWVALVTGAFRGLDHADGVVGTVGVVTAFGVGACAAVELMDGPAVLLLVLAAALAGFLLHNWHPARIALGACGSLFTGFLLTGAAVLARTGYGPVGGAGVLCALTAVPVADAVLVLLSRRLAGRPLSRGGPDHLAHRLRRLGLTAQGVVVVLGGAALCAVVVGVLAHTGRVGGQAALWVAGGAAAGVLGLLRVRVYGPARLRRGAGVRAPVRRAGRGARAWAVVRRPRTAMRRARAGVSQAPRGATGAAGGASFRAAIFPVRQATSTENVQVGAPLRVRNG
What are the official names of this protein?
Putative glycosyltransferase SCO3672.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PA2AA_CALRH
Sequence: VEGSLVQFETMIMKLAKRSGFFWYSFYGCYCGWGGHGLPQDPTDRCCFVHDCCYGKVTNCNPKTATYSYTEENDGIVCGGDDPCKKQVCECDRVAAMCFRDNKDTYDSDKYWKLPPQKCQEDPEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits ADP-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 S1E6-a, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: A16A1_RAT
Sequence: MAATRIQPSTREIFTTLEYGPVPESHACALAWLDTHNRLLGHYVNGMWLKPEHRNPAPCQDPITGENLASCLQAEAEDISAAVEAARITFKTWSQLPGTARGQHLTRLAKVIQKHQRLLWTLESLVTGRAVREVRDGDIPLAQQLLHYHALQAHAQDSALADWEPLGVIGLILPTSFSFLDMMWRVCPALAMGCTVVALVPPSFPTPLLLAQLAGELGSFPGILNVVCGPVSLGPVLASQPGVQKVAFCGAVEEGRALRQTLAGRGATLGLALGTESLLLLTDSADVDSAVEGVVDAVWSDRSLGGLRLLIQESVWDEAMKRLQARMAQIRSGKGLDGAVDMGARGAAARDLAQSFVDEAQSQGGQVFQAGDMPSNSPFFSPTLVSGLPPAAPCAQAEVPWPVVMASPFRTVKEALALANGTPRGGSASVWSERLGQALELGYGLQVGTVWINAHGLRDPAVPTGGCKESGSSWHGGPDGLYEYLQLLGTPYRESFLCESLNYDTFGLAVSSSLPSGPETGPSPAPPYGLFVRGRFQSPGTQSSRPIKDSSGKVSSYVAEGGAKDIRGAVEAAHQAAPGWGAQSPRARASLLWALAAALERRKQVLAAQLERHGAAPTVAETEVELSVRRLQTWATRVQDQGQTLQVTGLRGPVLRLREPLGVLAVVCPDEWPMLAFVSLLAPALAHGNAVVLVPSGSCPLLALEACQDIAALFPAGLVNVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWVNRDFPRAWDVEVQGSEQELSLHAARTKALWLPMGD
What are the official names of this protein?
Aldehyde dehydrogenase family 16 member A1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: DEOD_HELPY
Sequence: MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: PHIG1_PHIGI
Sequence: LPASVDWRKEGAVLPIRHQGQCG
What is the function of this protein?
Thiol protease.
What are the official names of this protein?
Philibertain g 1, Philibertain g I.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.