PharMolix/UniProtQA huggingface dataset:
Protein: DTSPH_IXOSC
Sequence: MIRIFALITALAITVKCQDDRRPFYVIGHMVNSIPQVSQFLELGTNAIESDVEFSENGTALRTFHGLPCDCLRRCKESADIVDYFQYIRNVTGFRHSEYSEKLLLVFLDLKVSKLPPESKYAAGVDIATKLVLHLWDGVPFYDAMNVLLSIGRASDMAVLTGAIDTIIGFDPSLSLFNHVGFDVGLNDKLENIAKMYERLGVNGHRWQGDGITNCLVNLRSPLRLKETISYRDTNKRESYVDKVYYWTVDKVATIRKTIRRGVDAIITNRPKRVTGVLEEDEFKKTVRPATYRDDPWMRLQSKTTGRGNELDSDMDEMGDEASEFDFEPFSYPLSPRRPLSSRSPAIRDSYNVWPQYNPLSPFY
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  Acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SPH, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLU_ECO24
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQTIIIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_VIBC3
Sequence: MSTQFDSAPFLKTVTNQPGVYRMYNAEAEVIYVGKAKDLKKRLTSYFRKNLDSEKTKALVSNIAKIDVTVTHTETEALILEHNYIKQYLPKYNVLLRDDKSYPYIFLSAHKHPRLSSHRGAKKRRGEYFGPYPDSGAVRETLHLIQKIFPVRQCEDTVYSNRTRPCLMYQIGRCAGPCVKGLISDQGYQEIVHYLRLFLQGKDNQVLSILVEKMEQASRELRFEDAAKARDQIQAIRRVQEQQFVSDDSLEDLDVLGFAQENGIACIHILMIRQGKVLGSRSHFPKIPSDTSQVEVFESFLSQYYLSHSEARSIPARIILNRGLTEETEALQIAISELAGRKVTFHVNPTGTRGRYLKLANTNALTAITTKMNHKMTISQRFKALQEELGMDAITRMECFDISHTMGESTMASCVVFNQEGPLKQEYRRYNITGITGGDDYAAMAQVLERRYSKQLDSSKIPDIIFIDGGKGQLNRAYEIISSCWQDWPKYPKIIGIAKGVTRKPGLETLITIDGDEFHLPSDAPALHLIQHIRDESHNHAIAGHRAQRGKTRRTSTLEGIEGVGPKRRQALLKYLGGMQELKRASVEEIAKVPGISHALAENIYQALKQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF355_IIV3
Sequence: MENNKKKLILLDLDNTLICAEDLDTVKDKKRLSQAQKQFRTVRMEDYYDIFERPHLQEFLDYLFKNFKVGVWTASSKDYAIFVIKNFITAPQNKVKPDRKIEIFLCSHHCNVSKKYFKGISKDLKLVTDQWKIIDLSQVKLVDDLEKLANHQPENVIHVKPFFYDEPNSKNDTELLKVQKTLETFK
What is the function of this protein?
May function as a phosphatase.
What are the official names of this protein?
Putative CTD phosphatase-like protein 355R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 355R family.
Protein: PAE6_ARATH
Sequence: MRSLLLWIAVVVCLLCSVAAVVQSGSSDGFGKPRDTETAISFLEYKLMAPSVPMIPLTLIHGADSKGAVCLDGTLPGYHLDRGFGSGANSWLIQLEGGGWCNNHRSCVYRKTSRRGSSKFMEKALAFTGILSNRSEENPDFFNWNRIKLRYCDGASFSGDSQDESSQLFYRGQRIWQVAMEEFLSLGMKQANQALLSGCSAGGLASILHCDEFRELLPSSTKVKCLSDAGMFLDSVDVSGGHSLRNMFQGVVTVQNLQKDLSSTCTNHLDPTSCFFPQNLVSDIKTPMFLLNTAYDSWQIQESLAPPTADPGGIWKACKSDHSRCNSSQIQFFQEFRNQMLFAVNSFSNSDQNGLYINSCFAHCQTERQDTWFAQDSPQLNGKRVAESVGDWYFDRAKNVKAIDCPYPCDTTCHNLIFE
What is the function of this protein?
Hydrolyzes acetyl esters in homogalacturonan regions of pectin.  In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions.  Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
What are the official names of this protein?
Pectin acetylesterase 6.
What is the protein family that this protein belongs to?
Belongs to the pectinacetylesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PHOSP_VSIVA
Sequence: MDNLTKVREYLKSYSRLDQAVGEIDEIEAQRAEKSNYELFQEDGVEEHTKPSYFQAADDSDTESEPEIEDNQGLYAQDPEAEQVEGFIQGPLDDYADEEVDVVFTSDWKPPELESDEHGKTLRLTSPEGLSGEQKSQWLSTIKAVVQSAKYWNLAECTFEASGEGVIMKERQITPDVYKVTPVMNTHPSQSEAVSDVWSLSKTSMTFQPKKASLQPLTISLDELFSSRGEFISVGGDGRMSHKEAILLGLRYKKLYNQARVKYSL
What is the function of this protein?
Essential component of the RNA polymerase transcription and replication complex.  Binds the viral ribonucleocapsid and positions the L polymerase on the template.  May act as a chaperone for newly synthesized free N protein, so-called N(0).  Plays a role in virion assembly.
What are the official names of this protein?
Phosphoprotein, P protein, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus protein P family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CNO10_DROME
Sequence: MDSAESPTKTQAGEDENYSLLCQAHEQFNNSEFDRCLELLQELETRGESSGPVLRHNRAVVSYYKTGCTQHSVLLKELEALTADADAPGDVSSGLSLKQGAAAATVARYNRAVIYYHRHMFGTALEKLAPLVARLEALEKAMAALVATLQLQLLLATNQLNRAEAFLDYLQYKLNLVATAPSSNAAEEAAVVGTAPPSAATNSSVVASPGGAAVEGAVPGLGGSLQLLQLITLVLNRKPVVIQEDGTPEYAALKAQQYYIMKDFQMAAKQLMRINNECTQAGTITPQLSTCIANNMGVIHLRVRHYAIAAKFFQNALNFDQQLARNLRQSTLQTMSSARSCEILYNLGVAMLHLRRPKEAFQCFLVPVKQFHSNPRLWLRMAEACIMEHEAKLVEEERQSQSETPSTKPYAPQSAGVPEPTLEFAVLCLRSALTLTQHYKTRFHMAAVSSEDVEAPEPKDPTQESWRHPQDNNFCNPSKPVSLESLENMMAAIYAAHSFVSLRLGDHVTALEMSEKLLACERLSDAHKLLGHMYAGEALMLMDKASEARDHLDPTFVGTLNAFDFETRDWQLKSVDAAQNVVRYNLAVAMALQNDLPQAKALLANLTHSLVANKALALRRFMDLKMGPVPGGTPS
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Is not required for association of CNOT7 to the CCR4-NOT complex (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 10, CNOT10.
What is the protein family that this protein belongs to?
Belongs to the CNOT10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FJX1_XIPMA
Sequence: MRALSANLFAVLLMCALASVFYVWSALENRLERHKRGSSVPDGGSFHQGPSEDHSAKTFRALLAVPVAQRQNSAGRSKAQNLTNPSAFVGSRDYHVNGDDERSAQREGPVKLGYPVDDGIFWSNWLEDVLPVRFTEGYAEAWRSKARTSPVVKLEPGCGRISNQLATFADGTKACVRYGINADQVQGETLTYYLASLLGITNLPPLVLSQLNGDSAQWVAVRTRINNLQWSDRAVVSLTEWISNLTGVVTPAPLRQESSGLLPALRCFENKTTAELLELMQWSDLIVFDYLTANFDRLVSNLFSLQWDPHVMERDTNNLLKTPHGDLVFIDNEAGLVHGFRVLNMWEKYHHSVLSSVCVFRKRTMQRVAELHRRRDSRQRLLELYRDSEPLSQELGFLSDEHAAVLQDRIDQLYKHIMQCKEKYNQL
What is the function of this protein?
May act as an inhibitor of dendrite extension and branching.
What are the official names of this protein?
Four-jointed box protein 1, Four-jointed protein homolog.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_MALP2
Sequence: MPKKAEAKTGSSSKTTKRTVAKKDVKAEVNETNKTAEKVSSKKVNKTANSVDTNESSSNSTPSTGSKFELSSFKEKVAEIENNILQKIKENPTITGKPFRKLVSVNKLMETGAHIGLTTRKWNPKMKKFIYTKKGNNHIIDLLHTVISLNVAYNFLLDLVKANSNSESSPVLIVGTRGKTIKNHVKEQAKRSHAFYINERWLGGTLTNFSTITKSVAKFNNLILIHKNGEINKYTKKEQVELKKKTEKYAKYFSGIRTMKELPKVIILTDPEINKIAIKEARNLGIPVIAICNTNANPDLVDYVIPANNHSIKSVYLLVGLLCDAVAEAKGLPKAFAEKKDEEILLPEVIKRKPENRRQNNHSFNKN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y1403_YERP3
Sequence: MKKKYHLTPDELQLFKESIAGAKKLRQDTIVHHTPPKLGKKIAPERLLQEQVDASYYFSDEFQPLLDTDGPTRYVRPGVDNFEVKKLRRGDYSPEMFLDLHGLTQKQAKQELGALIAACKREHVHCACVMHGHGKHVLKQQTPLWMAQHPDVLAFHQAPKEWGGTAALLLLIELEE
What are the official names of this protein?
UPF0115 protein YpsIP31758_1403.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: AROE_BRUA2
Sequence: MDDKSMARGRKAFVTGFPIRHSRSPLIHGFWLKELGIDGSYEAVEVKPEDFSSFAASLAANGFAGGNVTIPHKEAAYAAAESLDEAARAIGAVNTLWLENGRLCGGNTDAYGFAANLDASAPGWDKADRALVLGAGGASRAVVHALLSRGVCHVSVVNRTLSRAEELAAHFGARVYAHSWDEAQALVSNAGLIVNTTALGMSGHGEGQDFPIDLTCAPKEAVATDIVYVPLRTAFLNKAEKAGLKTVDGLGMLLHQAVPGFERWFGQRPQVTQALREHILADMAKAGAL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: FABZ_SALTI
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity).
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_SHEPA
Sequence: MAAKELSHLQQLEAESIQIIREVAAEFDNPVMMYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTDWKFKEMIAFRDEQAKEFGFELLVHKNPEGLEMGISPFEHGSAKHTDIMKTQGLKQALNKYGFDAAFGGARRDEEKSRAKERVYSFRDKHHTWDPKNQRPELWRTYNGAVNKGESIRVFPLSNWTELDIWQYIYQENIQLVPLYFAQKRPVVERDGMMIMVDDDRMPLAEGEQPKEELVRFRTLGCYPLTGAMHSEADTLEKIIEEMLLTRSSERQGRLIDSDQSASMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: IPK1_ORYSJ
Sequence: MEVVLHEGDAKDWVYKGEGAANLILSYTGSSPSMLGKVLRVKKILKDKGQPAPNCIVFSSHEEHLWGKIPGLLESVKNDCLPQAYATIVMSQHLGANHVDGGVRVRVSKNFFELAGKNVLDNRPAWRVNASAIDAGADSALLISDHTLFSGNPRGSSCIAVEIKAKCGFLPSSEYISKENSIKKQVTRYKMHQHLKFHLGEISKTSEYDPLDLFSGSKERIHMAIKSFFSTPQNNFRIFVDGSLVFGGMGGGADSVHPNETEKCLEDLSKVTGLQLSDFIELLSEAIFKSGVLGKLLATQKLDDHDIEGAIHLYYNIISQPCLVCKSITDTELLRKYSTLHSLPLDKSEKIVRDFLISATAKDCSLMISFRPRQSGTTDSEYDSVFLDSVNQSYDYKAYFIDLDVKPLDKMVHYFKLDQKIVNFYTRNGEVGGDPRDPPKGCGPR
What is the function of this protein?
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).  Phytate is a regulator of intracellular signaling, a highly abundant animal antinutrient, and a phosphate store in plant seeds.  Also phosphorylates Ins(1,3,4,6)P4 and Ins(1,4,5,6)P4 to produce Ins(1,2,3,4,6)P5 and Ins(1,2,4,5,6)P5.
What are the official names of this protein?
Inositol-pentakisphosphate 2-kinase IPK1, Inositol-1,3,4,5,6-pentakisphosphate 2-kinase IPK1, OsIPK1, Ins(1,3,4,5,6)P5 2-kinase, InsP5 2-kinase 1.
What is the protein family that this protein belongs to?
Belongs to the IPK1 type 2 family.
Protein: MU135_SCHPO
Sequence: MSEEDNRLNELFANDLGVQPPCERSLKEGRRFLNDFEIAAKKKLLELERKALEDKEKNLNFVVESERTLFNSKKRAFDNDECYNDRCKLFRGIVNEWGRSERTLDSLDEPPAWFRREMGEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKEWRNSMDEWRKSMDEWRKSMDEWRKSMDEWRKSTDEWRKSTDERLENLLNIVREILDVQRDMRNDLSNLTRKVDRMDMRLSRNNNMIMRSFAQPITEVPFFNGDIPDPNLPRITRIEDIDSLSEENCTRYLKGYGVSYDENDQSLWKRQLAKAVGLTAAYDESYTFSPFSSSE
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 135 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0612 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FETP_STRM5
Sequence: MSRTVFCQYEQRDAEGLDFVPYPGELGQRIFNNIGKQAWAAWLAHQTMLINENRLSPRTPEHRAFLEGELVKFLFEKDAEKPAGFTPEA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: EI3F2_DROPS
Sequence: MSLSNFNLQSKVLLHPLVLFQIIDAYERRAKDVPEVLGTLLGTVAGKTGRIEITNCFSVVHRMHGDNNCHIDLDLKYDNDMLELAQIAYPQEKVLGWFSTGKSVSAAAVELHEYYERQCHNGQPLHLLMDTSLRGQRMNTRIFCAVATGVPGGTKGLMFSLLPMDIYFGSPDIVAMRHMGRQCAQPTKDAGRLLPELEQVVDATKDIQQKLDLVLRYINDILNRKRRPDNTVGRALHDVLTSVPMVEAERFRHMFNTNMRDLLMSLTLSSMIKTQLQLSERLSNMVDA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F-2, eIF3f-2, Eukaryotic translation initiation factor 3 subunit 5-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_SHEPC
Sequence: MSNIPTELKYASSHEWIRKEEDGSYTVGITEHAQELLGDMVFVELPEVGDTVTAGDDCAVAESVKAASDIYAPISGEVIAVNEALEDSPELVNSDAYGEGWFFRVMPSDETEVDALLDAEGYQAVIDEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: SPEF1_XENLA
Sequence: MAVEFDEETMQELYTWVDTIPLSRPKRNIARDFSDGVLTAELVKFYFPKLVEMHNYVPANSTTQKLSNWTILNRKVLSKLSFSVPDDVIRKIVQCSPGVVELVLNTLRQKIEEKQRLHHISADLSQDQATQNNGNTHSDKGYKSNGTELSPRQGARVDPASKTHQGYAQAANADTTLRFQLAEKEQTLILSQETIQILQAKLRRLEQLLLLKNVRIDDLTRRLQELEKK
What is the function of this protein?
Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation.  Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (PubMed:25070955).  Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity).  Essential for ciliary central apparatus formation which requires both its microtubule-binding and bundling activities (By similarity).  Regulates planar cell polarity signaling pathway and asymmetric microtubule accumulation in ciliated epithelia (PubMed:29514918).
What are the official names of this protein?
Sperm flagellar protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Apical cell membrane. Note=Also found at the apical tip of cilia.
Protein: MNMG_SYNE7
Sequence: MPHTEEFDVIVIGAGHAGCEAALAAARLGCQTLLLTLNLDRIGWQPCNPAVGGPAKSQLAHEVDALGGEIGKMADRTYLQKRVLNASRGPAVWALRAQTDKREYAAVIKQVLEQQPNLRLREGMVTDLLIGPNDEVQGVTTYFGSSFRAKAVILTTGTFLGGCIWVGNKSMPAGRAGEFAAVGLTETLQRLGFETDRLKTGTPARVDKRSVDYSRLEPQPGDPEVRWFSFDPEAWVEREQLPCYLTRTTAETHKLIRDNLHLTPVYGGYIDAKGPRYCPSIEDKIVRFADKESHQIFIEPEGRDIPELYIQGFSTGLPEDLQLALLQTLPGLEDCVMLRPAYAVEYDYLPATQCLPTLMTRRVEGLFSAGQLNGTTGYEEAAAQGIVAGINAARFVQGQDAIVFPREGSYIGTLIDDLCTKDLREPYRVLTSRSEYRLLLRADNADQRMTPLGREIGLIDDRRWALFEQKQARIAAEQTRLTQQRVKEHDPVGQAIAQQTQAPIKGSATLADLLRRPNFHYIDLEAHGLGDPSLAIAEKEGAEIAIKYAGYLQRQQAQVDQVVRQSQRPLPVDLDYSAITSMRLEAREKLARFRPLTLGQASRIGGVNPADINALLIWLEVQERQRSQVETALVR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_YERPN
Sequence: MVDNNKTVDNNYKHTSVLLDEAVKGLNIRDNGIYIDGTFGRGGHSRLILSQLGPEGRLIAIDRDPEAIEAAKQITDPRFSIVHGPFSDLAHYVRDLDLVGRIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFGEERFAKRLAKAIVERNLTQPMTRTKELADLIANASPFRDKHKHPATRSFQAIRIYINSELEEIERALDGAHEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKSVGKMMPGDAEIAENPRARSSVLRFAERIGE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MARR_SALTY
Sequence: MKSTSDLFNEIIPLGRLIYMVNQKKDRLLNNYLSPLDITATQFKVLCSIRCAGCITPVELKKVLSVDLGALTRMLDRLLCKGWIERLPNPNDKRGVLVKLTPDGAAICEQCHQRPGQDLHQELTKNLTADEVATLEYLLKKILP
What is the function of this protein?
Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes.  Binds to the marO operator/promoter site.
What are the official names of this protein?
Multiple antibiotic resistance protein MarR.
Protein: RS18_ALKCK
Sequence: MARRGRPKRRKVCFFTANKITHIDYKDVDLLKRFISERGKILPRRVTGTSAKYQRKLTVAIKRARQVALLPYVNDVN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SYP_PERMH
Sequence: MRASQYFIPTLKEAPAEAEVPSHIYLIRAGFIRQLAAGLYEYLPLGFRVLKKIEGIIRKYMDDAGALEVLLPILAPAELWQETGRWDVYGKELFRVEDRKGRFFALGPTHEETITDLVRKNIRSYKDLPKNFYQIQTKFRDEARPRYGLIRGREFIMKDAYSFDISEEMAVKSYEIMKEAYKKIFDELGLDYLMVEADVGAIGGKYSHEFVVKVPNGEAHIVFCDNCGYAANVEAAKYEFELDKLPPEDEKPLEKVHTPGVSSVEDVSRFLDINQKKIVKTLVYILDDGTAVAVLIRGDRELNETKLINYFKALDCHLASSEELKDLGIVEGFVGPMGLDIPVYADISVKDLHNFVVGANEEDYHYINVNIPRDFKPVDFVDFSTAREGDPCPVCKKPLNETTGLEVGHIFLLGTKYSEALKAYFVDKDGREKPIVMGCYGIGVSRLMAAAVEQSHDENGIIWPENIAPFKLHILALNIKDDQIKTVAEDIYTKAKEKGIEVLFDDRDISPGAKFKDADLIGIPYRIVVGRGVKNGKVEIQTRKDGKKEEIDINEIDNFLDRL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_AZOPC
Sequence: MATKIRLQRHGRKGYAFYHIVIADSRAPRNGNFIERIGFYNPNTNPATINLKFERALYWLNVGAQPTDTARNILSCEGIFLKKHLLEGINKGVLSEADAKSKFEAWKNVKRIAIQNEINKIYEQQRIVNKAKLESERVVNQTKTKVLAQKEKLLKEENNTPLPSE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: AGRB_STAAW
Sequence: MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFIFTLITNISFYLIRRYAHGAHAPSSFWCYIESITLFIVLPLLVLHFHINETLMMFLALISVGVVIKYAPAATKKKPIPARLVKQKRYFSIIISTILFIITLFVKEPYTQFIQLGIIIQAITLLPIYYSKED
What is the function of this protein?
Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP).  This quorum sensing system is responsible for the regulation of the expression of virulence factor genes.  Involved in the proteolytic processing of AgrD, the precursor of AIP.
What are the official names of this protein?
Accessory gene regulator protein B.
What is the protein family that this protein belongs to?
Belongs to the AgrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPH_STAAR
Sequence: MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYEAYGSQFGDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: SURE_HALS3
Sequence: MDADEPEILVTNDDGIDAPGIRALADGLDAVGNVTVVAPADNQSATGRAMSQEVAVHDHDLGYAVEGTPADCVVAGLEALGPYPDLVVSGVNEGGNLGMYVLGRSGTVSAAVEAAFFGVPAIAVSMYMREEQFGEPTAVADYEHAVDATTHLAHDAVTDGIFDTADYLNVNAPHPDADATGEMVVTRPSHAYDMTAAQTGDTVTLYDRLWEAMAAGDIHDPDGTDRRAVLDGHVSVSPLTAPHSTEHHDALDGIATEF
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.