PharMolix/UniProtQA huggingface dataset:
Protein: PSA2_HUMAN
Sequence: MAERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVKDYLAAIA
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-2, Macropain subunit C3, Multicatalytic endopeptidase complex subunit C3, Proteasome component C3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
Protein: MTNC_PARMW
Sequence: MSITHLLIDIEGTTCPVSFVSEVLFPYAKQSLSSYLNDHQEDLDLKNILQEAEREWDGDPSPDSIKLRQATRNQNLNFIDSIKVYFEYLINVDRKSTALKDLQGKIWDNGYRKGEITSHLFNETTECLKRWHRRQLSLSVYSSGSIQAQKLLYRHTNDGDLEHLFDHWFDTHTGNKKECASYRKIATKISTNPSEILFISDNGEECDAAGASGMETLFSLRDGNPDQSPRSHRVIKTLNDVDEYL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: CCR1_PETHY
Sequence: MRSVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCKADLLDYQSLREAINGCDGVFHTASPVTDDPEQMVEPAVIGTKNVINAAAEANVRRVVFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYGKMVAEQAAWEEAKEKGVDLVVINPVLVQGPLLQTTVNASVLHILKYLTGSAKTYANSVQAYVDVKDVALAHILLYETPEASGRYLCAESVLHRGDVVEILSKFFPEYPIPTKCSDVTKPRVKPYKFSNQKLKDLGLEFTPVKQCLYETVKSLQEKGHLPIPTQKDEPIIRIQP
What is the function of this protein?
Involved in the latter stages of lignin biosynthesis (PubMed:24985707).  Catalyzes one of the last steps of monolignol biosynthesis, the conversion of cinnamoyl-CoAs into their corresponding cinnamaldehydes (PubMed:25217505, PubMed:24985707).  Mediates the conversion of feruloyl CoA to coniferylaldehyde (PubMed:25217505, PubMed:24985707).  Also active toward p-coumaroyl-CoA and sinapoyl-CoA (PubMed:25217505, PubMed:24985707).  Involved in the production of floral volatile phenylpropanoids in flowers of fragrant cultivars (e. g.  cv.  Mitchell and cv.  V26) from cinnamic acid, a common precursor with the anthocyanin biosynthesis pathway involved in flower pigmentation (PubMed:24985707).
What are the official names of this protein?
Cinnamoyl-CoA reductase 1, Ph-CCR1, Coniferylaldehyde synthase, Coumaroyl-CoA reductase, Feruloyl-CoA reductase, Sinapoyl-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_PSYIN
Sequence: MKIGIIGAMDEEVSILKAKLNNMETTIIAGCEFYQGELNGKQVILTKSGIGKVAAAVATTLLLERFNPGQVINTGSAGGYDTTLNVGDIVISTEVRFHDVDLTAFGYEIGQMAQLPAAFPADKNLIFAAQKAAETITHLKTIQGLICTGDIFMADPTKAEIARHNFPTMAACEMEAAAIAQVCYQFKVPFVIIRSLSDIAGKKSELSFEQYLPIAAKNASILVEEIINNLN
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: ERA_ECOLU
Sequence: MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: KCY_SHESH
Sequence: MSERAPVVTIDGPSGAGKGTISQLLAERLGWKLLDSGAIYRVLALAAIHHNVELDNEDSLSLLAAHLDVQFITGNGLHGIKVVLEGEDVSIDIRSQECSNAASKVAAYPRVREALLRRQRAFNEAPGLIADGRDMGTVVFPNTPAKIYLTASAEERAQRRYNQLQDKGFDVNIDRLLSEIIERDDRDTNRSVAPLVPAEDALIIDTSGIGIDEVLDIALTHIQTKLPSVS
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HARB1_HUMAN
Sequence: MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGANLSRPTQRSRAISPETQVLAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIRFPADEASIQALKDEFYGLAGMPGVMGVVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLMVCDIRGTLMTVETNWPGSLQDCAVLQQSSLSSQFEAGMHKDSWLLGDSSFFLRTWLMTPLHIPETPAEYRYNMAHSATHSVIEKTFRTLCSRFRCLDGSKGALQYSPEKSSHIILACCVLHNISLEHGMDVWSSPMTGPMEQPPEEEYEHMESLDLEADRIRQELMLTHFS
What is the function of this protein?
Transposase-derived protein that may have nuclease activity (Potential).  Does not have transposase activity.
What are the official names of this protein?
Putative nuclease HARBI1, Harbinger transposase-derived nuclease.
What is the protein family that this protein belongs to?
Belongs to the HARBI1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Interaction with NAIF1 promotes translocation to the nucleus.
Protein: CINA_BACMK
Sequence: MNAEIIAVGTELLLGQIANTNAQFLSEKLASIGINVYYHTVVGDNNKRLQKAIELAEERADMLIFTGGLGPTKDDLTKETIASTLDEELVYDEKALTSISDYFKRTGREFTENNKKQALVLNGSTVFANDHGMAPGMGLNTNGKVYILLPGPPKEMKPMYISYVEPFLCKFTTGENIYSRVLRFFGIGESQLEVKVQDLIDGQTNPTIAPLANDGEVTLRLTAKHHDADEAEKLIQHVEDLILERVGEFFYGYDQDFLHYKAIRLLKEKGLTLACAESLTGGLFGNQVTENAGVSSVFKGGVICYQNDVKQQILHVPEEVLRTDGAVSKQCARYLAENVKKLLKADIGISFTGVAGPDASEHKEPGTVFIGLVIKDEPAVVFSLNLSGSRQQIRERSTKYGFYHLFKKLEEI
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: Y2611_LISMC
Sequence: MINNYIDITVRLLENILDNEADYVKEAGAKVAESIENDGVIHLFGCGHSHILTEEVFYRAGGLAAIHPILHEPLMLHEGAAASSVLERKNDYAKTFMAEEDIRPGDIMIVLSTSGRNPVPIDVAEIAREKGAFVIVITSLQYSASQKSRHTSGKRLSDAGDIVIDNGAVKGDAVLKSANFDIAFAPTSTVTGAVILQSIFAEAIETMVNDNFTPPVFISGNVENADAHNQALVDKYNERIPLLGMNL
What are the official names of this protein?
UPF0309 protein Lm4b_02611.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: RSMG_GEOSW
Sequence: MDTAQFHTMLEEKGISLSSQALAQFERYYELLMEWNEKMNLTAITDKPSVYLKHFFDSLSPAFYYDFSQSLSICDVGAGAGFPSVPLKICFPHLKLSIVDSLQKRITFLEHLAAELGLTDVAFYHDRAETFGRKKEFRESFDIVTARAVARMSVLSELCLPLVKVNGTFIAMKAASAQEELEQGKKAIDVLGGEISAIERFMLPIEQSERTIIFIQKVRNTPNKYPRKPGMPNKQPIQ
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FALX1_LITFA
Sequence: MASLKKSLFLVLFLGMVSLSICDKEKREGENEEEEEEHEEESEEKRGLLSFLPKVIGVIGHLIHPPS
What is the function of this protein?
Fallaxidin-4. 1 shows antibacterial activity against the Gram-positive bacteria L. lactis (MIC=12 uM), M. luteus (MIC=100 uM), S. epidermidis (MIC=100 uM) and S. uberis (MIC=50 uM).  No antibacterial activity against the Gram-positive bacteria B. cereus, E. faecalis, L. innocua, S. aureus, or the Gram-negative bacteria E. cloacae and E. coli.  Inhibits the formation of NO by neuronal nitric oxide synthase with an IC(50) of 13. 3 uM.
What are the official names of this protein?
Preprofallaxidin-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RF12B_XENLA
Sequence: MESADSTGKGSTEQSESQRQSQMDRLDREEAFYQFVNNLNDEDYRLMRDNNLLGTPGEITKEELLQRLQQIKEGPPQPSTEETRGDSVSTGEDPAEDSSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRTSGTASMPSLDQSAEMPGPEDMEVSSQGEAENVPEPETVPESIREPESVDEPVSVAEPVSVAEPVSVAEPESVAEPESVAASVPVPESVPEPESVPEPESVPEPESVPEPESVPEPESVPEPESVPEPESVPEPESVPEPESVPEPESVPEPESVPEPESIAEPESVPVPESVPVATRPAPVEVTVEEAPIQRGQRRARSRSPDQRRTRARTDRSRSPLYQTVDPPIRRAQHSSSQTVDASNTEEAEGSSRTRHHVSSQVHSSSSNETEGSSRTRQHITARQQALGTEGQSQSTVHLSNPESRSSSQTPQTDSPSNAETTGTGQRPPTIVLDLQVRRVRPGDYRQRDSIANRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYNDNDADPNNPTAVSPPAAVPGEVQNNPSAEVRAPIAEPAEPVAPVESDEGSNVATSATRREGRNSRGGVTLEESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLSTRNYGENDALKTCSVCITEYTEGNKLRKLPCSHEYHIHCIDRWLSENSTCPICRRAVLVAGNRESIV
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase specific for ldb1, mediating ubiquitination and proteasome-dependent degradation of excess ldb1 in a RING-dependent manner.  Does not degrade ldb1 bound to lhx1/lim1, nor lim1 itself and thus contributes to the establishment of proper ldb1-lhx1/lim1 stoichiometry and the formation of a ldb1-lhx1/lim1 complex.  Interferes with Spemann organizer function and suppresses secondary axis formation induced by ldb1 and lhx1/lim1 (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF12-B, RING finger protein 12-B, RING-type E3 ubiquitin transferase RNF12-B, XRnf12B.
What is the protein family that this protein belongs to?
Belongs to the RNF12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NKAPL_HUMAN
Sequence: MPPVSRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRESKILASFREMVHKKTKEKDDK
What is the function of this protein?
Transcriptional repressor of Notch-mediated signaling.  Required for spermatogenesis.
What are the official names of this protein?
NKAP-like protein.
What is the protein family that this protein belongs to?
Belongs to the NKAP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3198_CHRVO
Sequence: MTDYQNDDDGFVSKSQRKRDMDALQDLGRELVDLSKDTLKKMQLPEDLLTAVLDYKRFTANGALRRQMQYIGKLMRDVDPEPIREYLKVLKGESSEHIAWQHLLERWREKLMADDKALSDFLAAFPEGDPQQLRTLMRNARKELQDNKPPKAYRQLFQEIKALIPEPGKPRLWQKDEDEE
What are the official names of this protein?
UPF0307 protein CV_3198.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: GSTA3_CHICK
Sequence: MAAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEIDGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQCAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEEKKSDALSGFPLLQAFKKRISSIPTIKKFLAPGSKRKPISDDKYVETVRRVLRMYYDVKPH
What is the function of this protein?
Catalyzes the conjugation of GSH to a wide variety of electrophilic alkylating agents.  Also involved in the metabolism of lipid hydroperoxides, prostaglandins and leukotriene A4 and in binding of non-substrate hydrophobic ligands such as bile acids, a number of drugs and thyroid hormones.  This GST does not exhibit peroxidase activity.
What are the official names of this protein?
Glutathione S-transferase 3, GST class-alpha, GST-CL3.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU70_ORYSJ
Sequence: MDLDPEGLFRDDSDEDDDNVQEREANKEMVVYLIDASPKMFTPATKADEKEETHFHTIVNCITHALKTQIIGRSYDEVAICFFNTKEKKNLQELAGVYVYNVTEREPLDRPDARLIKEFSCIEDSFMSNIGSRYGITSGSRENTLYNALWVAQALLRKGSVKTVSKRIVIFTNEDDPFGGLTGAVKTDMIRTTIQRARDAQDLGLSIELLPLSRPDEEFNMSLFYADLIGLEGDEIVDYLPSSGEKLEDMTNQLKKRMMKKRKVKTLAFAITNDVCIEVNTYALIRSTTPGAITWLDSISNLPLKAERSFICNDTGALIQDPQKRFQVYNDKIVKFSTRELSDVKRVSSHHLRLLGFKPLDYLKDYHNLRPSTFIYPSDEQIFGSTRVFVALHSSMRRLGRFALAFYGNPTRPQLVALIAQEEVTSAGGQIEPPGIHMIYLPYSDDVRYPEEVHLTSDDAPRATDEQIKKASNLLRRIDLKNFSVCQFSNPALQRHYGILEALALGEDEMPDVKDETLPDEEGLARPVVVKAVEEFKASVYGENYDQEEAEAAAAKAGASKKRKALTDAAAEKSAAHNWAELADTGKLKDMTVVDLKSYLSAHGLPVSGKKEALVSRILTHLGK
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair.  When associated with KU70, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA (By similarity).  Required for the maintenance of chromosome stability and normal developmental growth.  Plays a role in maintaining telomere length.  Acts as a negative regulator in telomere homeostasis.
What are the official names of this protein?
ATP-dependent DNA helicase 2 subunit KU70, OsKU70, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the ku70 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPRD2_MOUSE
Sequence: MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEDMIVALREALMDRAASHNARLQKLQCFPGTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLMYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPVEKPAVSTGVPTKSTESVSKASPCAPPSVPTTAAPPLPKPLSTALLSPSPTLVLPNLANVDLAKISSILSSLTSVMKNTGVSSASRPSPGIPTSPSNLSSGLKTPAPATTPSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTANPVPASEVTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTSASKASVGQSPVLPSTTFKLPSSSLGFTGTHNPSPAAPPTEVAVCQSSEVSKPKPESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSEGHASDFQRGPTSTSVDSIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPQELPNSVSTYRPFGLGSDSPYKQPSGGVERPSSLMDSSQEKLFPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDATEYQPILSSYNHRAQEFGVKSAFPPSVRALLDSSENCDRLSSPPGLFGAFNIRGNEPGSERSPSPSKNDAFFTPDSNHSGLSQSTAGHLTLPQTQYPDSPHSVPHRSIFSSQSTLAAPAGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQTPNKGTSSDGVSLSNLTQPSLPTTDQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNAANRRMSGEPIKTVESIRVPGKGNRGHGREVSRVGWFDLSTPGSSFDNGPSSASELASLGGGGSGGLTGFKTTPYKERAPQFQESVTSFRSNSFNSTFEHHLPPSPLEHGAPFQREPVGPSSAPPAPPKDHGGIFSREAPTHLPSVDLSNPFTKEASLAHAGPPPPPGEHSGVPFPPPPPPPPPGELSSGGTGVPFATPAPPPPPVDHSGVVPFPTPPLPEHGVTGAVSVFPKDHSSLLQGTMAEHFGVLTGPRDLNGPGLNRSRESLSLPSHPLEHLGPALGGGGGGNTSSSGLPLSPAHRDAIGRSGMILRSPRPDFRPREAFLGRDPFHSLKRPRPPFVRGPPFFAPKRPFFPPRY
What are the official names of this protein?
Regulation of nuclear pre-mRNA domain-containing protein 2.
Protein: CYB_MYOAL
Sequence: MTNIRKSHPLXKIINSSFIDLPAPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFNSVTHICRDXNYGWVLRYMHANGASMFFICLYLHVGRGLYYGSYMYTETWNIGVILLFAVMATAFMGYVLPWGQMSFWGTTVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAAMVMVHLLFLHETGSNNPTGIPANTDMIPFHPYYTIKDILGLLLMITALLTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVIVPLLHTSKQRSMTFRPLSQCLFWLLTADLFTLTWIGGQPVEYPYVIIGQLASILYFSIXIILMPLTSLMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TPRL2_ERYCB
Sequence: MTSVAGPHKRLEGKVAIITGGASGIGACTAELFHENGAKVVIADIQDDLGQALATKLGGKACYIHCDVSKEDEVINLVDTTVAKYGRLDIMFNNAGIIEGQGLPVSVVESEKSDLDRLLSVNLGGAFLGAKHATRVMVQQRKGCILFTSSVCTSIAGLSGHAYAASKSGVCGLAKNLTPELGKYGIRVNCISPYGLVTGVSNVSGEGEANREFVEAMLSELGTLSGQTLRADGIAKAALFLASDEAYYVSGINMVVDGGYSVVNPRLVDSINSKL
What is the function of this protein?
Has no tropinone reductase activity.
What are the official names of this protein?
Tropinone reductase-like 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RL21_MALP2
Sequence: MFAIFEVGSKQYKVQKGDVIYVEKQDKKVGESISFDKVLMVDATIGKPYIKNATVSCKVEKQGKQKKIFIIKHKRYTRSLKRQGHRQPYTKLVVTGINVK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: S38A5_BOVIN
Sequence: MAISSAEGMELQDPKMNGALPGNAVEQEHEGFLPSHSPSPGRKPAQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGILLFLALLLCIALLSSYSIHLLLTCAGVVGIRAYEQLGQRALGPAGKVVVAAVICLHNVGAMSSYLFIIKSELPLVIATFLDMDPEGDWFLKGNLLIIIVSVLIILPLALMRHLGYLGYTSGLSLTCMLFFLISVIYKKFQLGCTVGHNGTAVESKSSPSLPIHGLNTSCEAQMFTADSQMFYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVEAEMLHMYSQHDLLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPLYSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSHVSGH
What is the function of this protein?
Symporter that cotransports neutral amino acids and sodium ions, coupled to an H(+) antiporter activity.  Releases L-glutamine and glycine from astroglial cells and may participate in the glutamate/GABA-glutamine cycle and the NMDA receptors activation (By similarity).  In addition contributes significantly to L-glutamine uptake in retina, namely in ganglion and Mueller cells and, therefore participates in the retinal glutamate-glutamine cycle (By similarity).  The transport activity is pH sensitive, Li(+) tolerant, bidirectional and associated with large uncoupled fluxes of protons.  The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+).  May have particular importance for modulation of net hepatic glutamine flux (By similarity).
What are the official names of this protein?
Sodium-coupled neutral amino acid transporter 5, Solute carrier family 38 member 5, System N transporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_NEIMA
Sequence: MQLTAVGLNHQTAPLSIREKLAFAAACLPEAVRNLARSNAATEAVILSTCNRTELYCVGDSEEIIRWLADYHSLPIEEISPYLYTLGMQETVRHAFRVACGLDSMVLGEPQILGQIKDAVRVAQEQESMGKKLNALFQKTFSVAKEVRTDTAVGENSVSMASASVKLAEQIFPDIGDLNVLFIGAGEMIELVATYFAAKSPRLMTVANRTLARAQELCDKLGVNAEPCLLSDLPAILHEYDVVVSSTASQLPIVGKGMVERALKQRQSMPLFMLDLAVPRDIEAEVGDLNDAYLYTVDDMVNIVQSGKEARQKAAAAAETLVSEKVAEFVRQQQGRQSVPLIRALRDEGEKARKQVLENAMKQLAKGATAEEVLERLSIQLTNKLLHSPTQTLNKAGEEDKDLVHAVAQIYHLDK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RECX_HAEIE
Sequence: MSSLAFNYIVNLLSRREYSEFELRNKMQEKNFSEEEIDEALSRCQAKNWQSDRRFSENYLNSRVQKGYGVGRIRQELRQLKGVSSDIIDEVLMESEIDWYEMAENLLRKKFPNYNEQQTPKMKQKIWQYMLSHGFRSDEFADLIGQNQSEWD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP1B_MOUSE
Sequence: MALAMQSSEFQFAQRLASSEKGVRDRAVRKLRQYLSARTQSDTGSFSQEELLKIWKGLFYCMWVQDEPLLQEELANIISQLIHVVNSLEAQYLFIQTFWQTMNREWQGIDKLQLDKYYMLIRLVLRQSFEVLKRNAWEESQITLFLDILMKEILSPESQSPNGVRTHLIDVYLEELTTVGGAELLADQNLKLIDPFCRIAAKTKDHTLVQTVARGVFEVIVDQSACVPQESVEERKTKEDGSGFPTKALACRKAVSGKKAALDECLRDGVIGSRERDICAALKDSGSPLQFDYKAVADRLLEIANSKSTPPFNRKRLCRLVRKFQDLCEGNGAPLSSAEDNGQRRHKRKRKKLLESEKGDTVSPAAEEDSGGHIHKKKRKKRKRSHFQPDTQNLDAVAVPKVPDSESEPDTAQRQAPCGQACVTEPTAEAVSSIGENSSKPTPVMPIHNKRKRPRKKKLRAHKEICKSTTLPQEDMSKNDAVSGHSQSSAAHISSSEGVQAQKRKRKLGALPDSSSDLPVQKSGTPTSPVEGKDGQTTLPRCKRSQKKTASSTLDPCDPSSQKPAISKKKKKTMKLMSNGVLESNPGQIQALGSNRTLKKPLKTEDDFVKFDTRFLPKPLFFRKAKNSSATRPQGPAGQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGLSRVAFNPEQRPLHGVLKTATSSPASTPLSPMRLPATTPKRRPRAADFF
What is the function of this protein?
Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1 (By similarity).  Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus (By similarity).  Involved in regulation of mRNA splicing (PubMed:23604122).  Inhibits SIPA1 GTPase activity (PubMed:18081427).  Involved in regulating expression of extracellular matrix genes (PubMed:18081427).  Associates with chromatin and may play a role in modulating chromatin structure (By similarity).
What are the official names of this protein?
Ribosomal RNA processing protein 1 homolog B, RRP1-like protein B.
What is the protein family that this protein belongs to?
Belongs to the RRP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Predominantly located in the nucleolus with a small amount found in the nucleoplasm. Associates with the perichromatin region during metaphase and with cytoplasmic foci during telophase before reaccumulation in the nucleolus during G2. Associates with heterochromatin and euchromatin.
Protein: YS045_HUMAN
Sequence: MHAGKRSPLTQSISCVCLPELGALWEIESARVNLRVSGREASREMESSPRPHRIAGVKRFLKHAGKWSLRWFLSPRWILQFRRWARKWSRFTRSSFQVRWAAVPAGKCSQHQGLSAVATASPGVFWEMEFDVSSPLTEGAGSPMSSKHAGE
What are the official names of this protein?
Putative uncharacterized protein FLJ42213.