PharMolix/UniProtQA huggingface dataset:
Protein: DHE3_MOUSE
Sequence: MYRRLGEALLLSRAGPAALGSAAADSAALLGWARGQPSAAPQPGLTPVARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPVVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT
What is the function of this protein?
Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate (PubMed:20670938).  Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (By similarity).  Plays a role in insulin homeostasis (PubMed:16959573).  May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
What are the official names of this protein?
Glutamate dehydrogenase 1, mitochondrial, GDH 1.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion. Endoplasmic reticulum. Note=Mostly translocates into the mitochondria, only a small amount of the protein localizes to the endoplasmic reticulum.
Protein: RS10_RUBXD
Sequence: MAVSKIRIKLKAYDHEVIDKTARSIVETAERTGAFVFGPVPLPTKRSRYTVIRGPFKDKDSREHFQLNTHKRLIDIQQPTPRTVDSLQRLDLPAGVNIEIKAT
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NPIIB_ARTBC
Sequence: MQVIVALAALGSLAAPALGFSIPRGVPVSQSMIDVKLSSTGNSMVKATITNNGNRALNLLKFHTIMDSNPTRKVSIESEDGKEIQFTGMMPTYKEKDLKPSYFISLPPKGTVEHSFDIARTHDLSRGGKFTLKAEGMVPIAEENGTEITGAAKYHSNELHMTIDGEKAASVENAFGIVKRGPLTRINKRTSIDMQSCGNSQELQALTAALKASAQLSSMSAQAVSQNQDKYMEYFKDPQYMQTVQSRFQAVAQESSSTTGGGTTYHCSDTMGGCEEGVLAYTLPSQNEVFNCPIYYSDLPPLSNECHAQDQATTTLHELTHNPAVQEPFCEDNGYGYERATALSAEKAVQNADSYALFANGKLNLITLMLIIDPD
What is the function of this protein?
Probable secreted metalloprotease that shows high activities on basic nuclear substrates such as histone and protamine (By similarity).  May be involved in virulence.
What are the official names of this protein?
Probable neutral protease 2 homolog ARB_05817, Deuterolysin ARB_05817.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AACUD_ASPA1
Sequence: MSKFEAFLRPTQTYHSRTYDRISKHHNFNGTGKTILVTGGSSGVGYSICQAFAEADVARIAIVSRSPGPQAAAKAALEAAHPAVQIVTYAASITDHARMAAILAELGPVDVLVLCAAVVHRQVPATAITAAEMQAAFDVNVLAPFHLVQAYLATTTAGTKTVIHVSSAAAQSRSPFRAGYGPSKAAATQVMQHFAAERASPALRVFSFHPGAFYTPSVAEHYAPDSTGWEDINLPAHFARWLAGPESGFLNGRYLWAHWDVDELIALRDRVERDSSFLTIGLVV
What is the function of this protein?
Short chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D (PubMed:30996871, PubMed:33891392).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase AacuL (Probable).  The atrochrysone carboxyl ACP thioesterase AacuM then breaks the thioester bond and releases the atrochrysone carboxylic acid from AacuL (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase AacuI, and oxidized by the anthrone oxygenase AacuG to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by a yet unidentified oxidoreductase (Probable).  A-ring reduction by the short chain dehydrogenase AacuN, dehydration by the scytalone dehydratase-like protein AacuK and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:33891392).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) AacuH then yields monodictyphenone (PubMed:33891392).  Monodictyphenone is transformed into compounds with the tetrahydroxanthone skeleton via methylesterification by the methyltransferase AacuQ, followed by the action of the flavin-dependent monooxygenase AacuC, the isomerase AacuP, and the short chain dehydrogenase/reductase AacuF or AacuD (PubMed:33891392).  AacuF and AacuD should accept the same compound as a substrate but perform the ketoreduction with a different stereoselectivity, thus yielding blennolides B and A, respectively (PubMed:33891392).  In the final step of the biosynthesis, the cytochrome P450 monooxygenase AacuE accepts blennolide B and/or blennolide A to conduct the dimerization reaction to furnish the tetrahydroxanthone dimers, secalonic acids D, B, and F (PubMed:33891392).
What are the official names of this protein?
Short chain dehydrogenase/reductase AacuD, SDR AacuD, Secalonic acid biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: NUOC_XYLFT
Sequence: MAEQTLSFVDCLMSRFPTVRVSVAQPRGEISLDVPVVEWCAVCKALRDEFDFEQLSDLCGVDYLGYGNAEWDTTDVSAQGFSRGVAGKAVGRFAWGEFPSAGSNDGTQPWDVPQERFAVLAHLISYRHNRRLRVRCFASNDALPIVASLTDVWPGVNWFEREAFDLFGIVFEGHPDLRRILTDYGFIGHPFRKDFPLTGNVEVRYDEEKKRVVYVPVTSVEPRVSVPRVIRDDPRFGAAAGESTHSETVK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DAPE_ERWT9
Sequence: MHCPVIELAQQLIRRPSLSPDDAGCQAILIARLQALGFTIETMNIGDTLNFWAWRGKGETLAFAGHTDVVPTGDVTRWNNPPFEPTIRDGMLYGRGAADMKGSLAAMVVAAERFVANYPQHEGRLAFLITSDEEASATNGTVKVVEALMARHERLDYCLVGEPSSTEVVGDVAKNGRRGSITANLTIHGVQGHVAYPHLADNPVHRAMPALNELVATEWDKGNEFFPPTSMQIANVQAGTGSNNVIPGDCFVQFNFRFSTELTDVMIQQKVQALLERHQLRYSIEWKLSGQPFLTSRGKLVDAVVNAVEHYNEIRPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKVDECVKAADLQLLSRMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: NTPP_RICCK
Sequence: MKWNQKNLPIVLASRSPARIELLNRIKIIPSHIIKADIDETPNLRELPAPLAVRLAYAKAIKVVSQIEESAIIIAADTVVAVGRRILPKATTYEEVKNCIKILSGRRHRVYTGLCIIKKENDRLTVRQKIAQTIVKFKKLSDEEINFYCSLDEGIDKAGGCKISGYAEAFIAFISGSYSNVMGLPLFETVNTLTSLGFKVYH
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_BACC3
Sequence: MQRFIKWLAVITSLDLLIVLLGGALVTKTGSGQGCGKSWPLCNGEFVPSNLSMETIIELSHRLTSGSAGILVTLLCILSWKYYKHVRETKTLAILSFVFLVAQALMGAAAVVWGQMPAVLAIHFGISLISFASVILLTCLIFEIDQKFDARSLIMDKKMKFHIYGVTIYCYLVVYTGALVRHERASLACPDFPLCSKNRPMPTQLHEWVQMGHRLAAMLIFVWILYAMILAIRHYKQQPVVYWGWIISFILVTLQAIVGILVVFTNASLAMALLHSLFISCLFAVLCYLVMLGTRSKVNAKEAASTSKQTK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENTB_ECO57
Sequence: MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAALREVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLSREVK
What is the function of this protein?
Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine.  The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms.  EntB is a bifunctional protein that serves as an isochorismate lyase and an aryl carrier protein (ArCP).  Catalyzes the conversion of isochorismate to 2,3-dihydro-2,3-dihydroxybenzoate (2,3-diDHB), the precursor of 2,3-dihydroxybenzoate (DHB).  In the enterobactin assembly, EntB functions as an aryl carrier protein phosphopantetheinylated near the C terminus by EntD to yield holo-EntB, which is then acylated by EntE with 2,3-dihydroxybenzoyl-AMP to form DHB-holo-EntB.  Then this product will serve in the formation of the amide bond between 2,3-dihydroxybenzoate (DHB) and L-serine.
What are the official names of this protein?
Enterobactin synthase component B, Enterobactin biosynthesis bifunctional protein EntB, Enterochelin synthase B.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the isochorismatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_STRP8
Sequence: MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDLSLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYGNKIDQLLRELDNKS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_ECOLI
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP (PubMed:15489502).  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25) (PubMed:15489502).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs (PubMed:15489502).  Also plays a significant physiological role in stress-response and is required for the survival of E. coli in stationary growth phase (PubMed:15489502).
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase, Stationary-phase survival protein SurE.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDIA6_MEDSA
Sequence: MKMEMHQIWSRIALASFAFAILFVSVSADDVVVLTEENFEKEVGHDKGALVEFYAPWCGHCKKLAPEYEKLPNSFKKAKSVLIAKVDCDEHKSVCSKYGVSGYPTIQWFPKGSLEPKKFEGPRTAESLAEFVNTEGGTNVKIATAPSHVVVLTPETFNEVVLDGTKDVLVEFYAPWCGHCKSLAPIYEKVAAVFKSEDDVVIANLDADKYRDLAEKYDVSGFPTLKFFPKGNKAGEDYGGGRDLDDFVAFINEKSGTSRDAKGQLTSEAGIVEDLDELVKEFVAANDEEKKAVFARIEEEVKKLEGSASRYGKIYLKVSKKYLEKGSDYAKNEIQRLERLLEKSISPAKADELTLKKNILSTYA
What are the official names of this protein?
Probable protein disulfide-isomerase A6, P5.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: SYT1_MOUSE
Sequence: MVSASRPEALAAPVTTVATLVPHNATEPASPGEGKEDAFSKLKQKFMNELHKIPLPPWALIAIAIVAVLLVVTCCFCVCKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK
What is the function of this protein?
Calcium sensor that participates in triggering neurotransmitter release at the synapse (PubMed:11242035).  May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (PubMed:7961887).  It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.  A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported.  It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.  Plays a role in dendrite formation by melanocytes (By similarity).
What are the official names of this protein?
Synaptotagmin-1, Synaptotagmin I, SytI, p65.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein. Cytoplasm.
Protein: PANC_PSEPG
Sequence: MNTVKTVRELRAAVARARGEGKRIGFVPTMGNLHSGHAALVTKAAQRADFVVASIFVNPLQFGANEDLDKYPRTLAADQERLLQAGCNLLFAPAVEEMYPDGMSVQTRVSVPQLSEGLCGASRPGHFEGVATVVSKLFNMVQPDLAVFGEKDFQQLAVIRAMVRDLNMPIQIIGEPTVRADDGLALSSRNGYLTPEQRTAAPALYRTLQHIAAGIGRGQRDFAALVAEGQAQLSAAGFRPDYLEVRHAVSLRPALIDDRDLVVIAAAYLGNTRLIDNLYLHLEEKTA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_PARMW
Sequence: MRVSLSWLKQLVQVTDSVEALAHRLSMAGFEEEEIEDLSARAKGVVVGFVKDREKHPNADKLSVCQVDIGSEESIQIVCGAKNVRAGLHVPVAMVGAELPAVNLTIKSGELRGVSSNGMICSLSELGLATESDGIAELDALTDELPALGAPVAPMLGLDDTVLELAITANRPDGLSMVGIAREVAALTGSALTLPVLTLKPAHELLQASAASAEAMQAGGLYGITLIEGVDGSQVSPTWVQQRLERAGINRVNAVVDITNVVMLEQGQPLHAFDADALEQLTGKPVNAASFGLRQAREGEAFIGLDGRELSLVARAQVVTCHDLPIALAGVMGSKASGVTAATGRIWLESAMFSPAAVRTTARSVGLRTDASARFEKGLPKEMTLACSIRALELLKELFPCEAKGLWVCGDSAADASSVLLRRNALHQLLGPIEDEEGSSDLADAVVEQCLTALGSELSPSDEGWNVIAPPSRRLDLAREIDLIEEVARLVGFDRFGAHLPDPLAPGALTPAQQAERRLRTLFCGAGLQEITTLSLVSASDSDPRIAISNPLLAETSHLRTNLWEEHLAVCVRNLKASQPGCWIFELGTTYAGSADAVEESRLLSGVICGEQRLERWTTSGKPAPPDYYAARGRLTEVMQALKLDVSDRRLTDDSRLHPGRAATLVLEGRPLGCFGQLHPELAASQNLPEATFLFELDLTRLVESATRRNRWVPAFKAFPTVPASERDLAVVVDRSQAASDLMQSIRKAGKPLLEAVTLIDRFEGDQLGENKASQAFRLRYRHQSETLTDDQVQPVHDKVRNALVKQHGAELRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_CHLAA
Sequence: MLNDVISEYEAHLKKATEALRHHLASIRTGRASSALVEHLHVEAYGMTMPLNQLANISVPEPRLIVIQPYDANMIKAIEKAIQQSDLGLNPSNDGRVIRLPVPPLTEERRRELVKMVRHRVEEVKISVRNQRRDAIDDLKKLEAEKLISEDELHRGQERIQQLTDRCTRELDQIGAEKEAEVMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y701_RICCN
Sequence: MHKNTHTKPDVNFYDKSGKTPLDWYSDYNATKIVETLIKNGGNVSSVYSRCSYS
What are the official names of this protein?
Putative ankyrin repeat protein RC0701.
Protein: LISC_SORBI
Sequence: MQSSLARPLRPPVLAGCGGRRGHGAPRGSVSVARCRAEAAPPTVGTASRAPAGPYTGRDPEVKKPAWLRQRAAQGDKYARLRESIGELKLNTVCVEAQCPNIGECWNGGGGAGGEGDGIATATIMVLGDTCTRGCRFCAVKTSNKPPPPDPLEPLNTALAVASWGVDYVVLTSVDRDDLPDGGSSHFAQTVRALKELKPGILVECLTSDFRGDLEAVSSLANSGLDVYAHNIETVRSLQRIVRDPRAGYDQSLAVLKHAKDCREGMITKSSIMLGLGETDEEVKQAMIDLRAIGVDILTLGQYLQPTERHLTVREYVTPEKFQFWKEYGESVGFRYVASGPLVRSSYRAGELFVQNLVRNNKTGSSSS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, chloroplastic, Lipoate synthase, LS, Lip-syn, Lipoate synthase, plastidial, LIP1p, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUCB2_CAEEL
Sequence: MLRAAGNLSKSMMKSQRRFLNLQEFQSKEILEKHGCSVQNFVVASNRKEAEEKWMSFGDHEYVVKAQILAGGRGKGKFINGTKGIGGVFITKEKDAALEAIDEMIGKRLVTKQTTSEGVRVDKVMIAEGVDIKRETYLAVLMDRESNGPVVVASPDGGMDIEAVAEKTPERIFKTPIDIQMGMTEGQSLKIAKDLQFEGKLIGVAAQEIKRLYDLFIAVDATQVEINPLVETADGRVFCVDAKMNFDDSAAYRQKEIFAYETFEEHDPREVDAHQFNLNYIGMDGNIACLVNGAGLAMATMDLIKLHGGEPANFLDVGGAVTEDAVFNAVRIITSDPRVKCVLINIFGGIVNCATIANGVVSAVNKIGLNVPMVVRLEGTNVDAAKQIMKKSGLKILTANNLDEAAAKAVSSLPK
What is the function of this protein?
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial, GTP-specific succinyl-CoA synthetase subunit beta, G-SCS, GTPSCS, Succinyl-CoA synthetase beta-G chain, SCS-betaG.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IF2B_ARATH
Sequence: MADEINEIREEQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSFTGMKKKKKKPTESSLLNNESVDAGEDLDEIANDEQEGEEGIVLQQRYPWEGSERDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKENRLFFLRCEKCGSQRSVAPIKTGFVARVSRRKT
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.  This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex.  Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit beta, eIF2-beta, Protein EMBRYO DEFECTIVE 1401.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: MURR_SHIF8
Sequence: MLYLTKIRNAESEFTGNEQKIADFLRARVSELKSVSSRQMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQHQ
What is the function of this protein?
Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc).  Binds to two adjacent inverted repeats within the operator region.  MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator.
What are the official names of this protein?
HTH-type transcriptional regulator MurR, MurPQ operon repressor.
Protein: DEF_LACH4
Sequence: MILMKDIVRDGDPVLRQVAKPLTFPLSDHYKQLAEDMMEYLVNSQDPKIAEKHQLRAGVGLAAPQVGEGVQMAALLVPDDKGEIIFKEVYVNPEIVSESVRQACLSEGEGCLSVDKVINGYVPRPDKLTIHYYTVDGEEKTIRLKDYPAIVSSHEIDHLNGHLFYDRINKKEPFALKEDTVVIS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: CECA_BOMMO
Sequence: MNFVRILSFVFALVLALGAVSAAPEPRWKLFKKIEKVGRNVRDGLIKAGPAIAVIGQAKSLGK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-A.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPSB_STRPF
Sequence: MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNAQIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVFGKQIIE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.