PharMolix/UniProtQA huggingface dataset:
Protein: ENO_MARSD
Sequence: MSTITAVWAREILDSRGNPTVEVEVVLESGATGRAAVPSGASTGTREALELRDGDKDRYKGKGVQVAVANVREEIAEALVGQDALRQVNIDNILIELDGTENKERLGANAMLGVSMAVARAGANLLGIPLYQYLGGVNGKLLPVPLMNIINGGEHAPNNLDIQEFMIMPIGAETFAEALRMGAEIFHTLKGLLAADGHNTAVGDEGGFAPNLESHAQAFEYIMKAIEAAGYRPGADVALAIDAAASEFYKDGKYVLAGEGKEFDAQGMIDFYTDFVERFPLISIEDGLAEGDWEGWKKMTDDLGEKIQLVGDDLFVTNPEILAEGIEQGACNSILIKLNQIGTLTETLDTMELAKTAGYTNVVSHRSGETSDHFIADLAVGLNAGQIKTGSLCRSDRLAKYNQLLRIEEDLEDDGIYYGPALKEAFFGED
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GAST_BOVIN
Sequence: MQRLCAHVLILVLALAAFCEASWKPHSHLQDAPVAPGANRGQEPLRMNRLGPASNPRRQLGLQDPPHMVADLSKKQGPWVEEEEAAYGWMDFGRRSAEEGDQHP
What is the function of this protein?
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes.  It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
What are the official names of this protein?
Gastrin.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_CAUVN
Sequence: MRVYYDRDADLARILDRKIAIVGYGSQGHAHALNLRDSGIKNVAVALRAGSPTAKKAEGEGLKVMTVAEAAAWADLIMILAPDEHQAAIYKNEIALNIRDGAALLFAHGLNVHFGLIEPKDTIDVLMVAPKGPGHTVRGEYQKGGGVPCLIAVHHNATGNALDLGLAYASAIGGGRSGIIETNFREECETDLFGEQAVLCGGTVELVRAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLEDIQSGKFVRDFMLENAVGQPSFKATRRRSAEHQIEEVGARLRGMMPWIAKNKLVDQAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: BPPBG_BOTJA
Sequence: QARPRHPKIPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent (By similarity).
What are the official names of this protein?
Bradykinin-potentiating peptide 11g, BPP-11g.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENGB_PSEA8
Sequence: MSEKNPIVGLCQKASFLISAAQVDQCPPDEGLEVAFAGRSNAGKSSALNTLTHANLARTSKTPGRTQLLNFFALDDSRRLVDLPGYGYAKVPIPLKQHWQRHLEAYLSSRASLAGVFLMMDIRHPLTDFDRLMLDWAQASQLPIHVLMTKADKLAFGAAKNALLKVRREVQQGWGDVATLQLFSAPKRQGIDEAQMVLAQWLGLLDEEQEAFEEA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HDEA_BRUO2
Sequence: MIKTLFNKNTALAAVAILALSGSAMAESAKTHKTDMAKKKVSELTCEDFNGLEESFKPTVVGWVVGFNKKGKEEDAVIDVDGIETVTPAIIEACKQEPKASFWKKAEAELKKVF
What is the function of this protein?
Required for optimal acid stress protection.  Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins.
What are the official names of this protein?
Probable acid stress chaperone HdeA.
What is the protein family that this protein belongs to?
Belongs to the HdeA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RPOA_GEOSL
Sequence: MYRNWRDLISPKKLQVESETLTNKYGKFYAEPFERGFGTTLGNSLRRVLLSSLQGAGITSVRIKGVLHEFSSIPGVTEDVTNIILNLKGVSLKMYGTEPKTVRIIHKGDGIITAGDIITDPQVEILNPEHHIATCSKDANLEMEMVVKVGKGYVPADRNRDEKAPVGTIPIDALFSPIRKVNFTVSNARVGQMTDYDKLTLEVWTNGSVIPEDAVAFAAKILKEQLSIFINFDEEAEPSGEAEVGEGESPINENLYRSVDELELSVRSANCLKNAGIKLIGELVSRTEAEMLKTQNFGRKSLNEIKDILAEMGLTLGMKLEGFPDPEVMRRLRGERKDEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PDRP2_ENTFA
Sequence: MTIFVISDSAGETASKLAAASMAQYPTVDFTLIRRTFVKDEDKLVQALEDAKKAEAMVLHTIINDHLVAIANQFFNEHQLFHFDILTPPVAEIERLTGVAPMREPGALHHLNENYFKRIEAMEFAVKYDDGKDPRGFLEADVLLLGVSRTSKTPLSLFLANKNLKVANLPLIPEAHLPKQLFEMDPKKIVGLTNDPNVLNGIRKERMRAYGLPENTSYSDIEKIRRELAFANDLYQKLGCIVIDVASLSIEETASMILNALNLEDHSYYSTETSED
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 2, PPDK regulatory protein 2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: SYS_SALSV
Sequence: MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDTLLAEIRNIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNELEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEAP1_RAT
Sequence: MQPEPKPSGAPRSSQFLPLWSKCPEGAGDAVMYASTECKAEVTPSQDGNRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASLSVPRNRSGGGVIDGHIYAVGGSHGCIHHSSVERYEPDRDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHSCIYAAGGYDGQDQLNSVERYDVETETWTFVASMKHRRSALGIAVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRLTSGRSGVGVAVTMEPCRKQIDQQNCTC
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination.  KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes.  In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine residues in KEAP1, leading to inactivate the ubiquitin ligase activity of the BCR(KEAP1) complex, promoting NFE2L2/NRF2 nuclear accumulation and expression of phase II detoxifying enzymes.  In response to selective autophagy, KEAP1 is sequestered in inclusion bodies following its interaction with SQSTM1/p62, leading to inactivation of the BCR(KEAP1) complex and activation of NFE2L2/NRF2.  The BCR(KEAP1) complex also mediates ubiquitination of SQSTM1/p62, increasing SQSTM1/p62 sequestering activity and degradation (By similarity).  The BCR(KEAP1) complex also targets BPTF and PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
What are the official names of this protein?
Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2.
What is the protein family that this protein belongs to?
Belongs to the KEAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic. In response to selective autophagy, relocalizes to inclusion bodies following interaction with SQSTM1/p62.
Protein: RIP_ATV
Sequence: MKNMLHPQKYETHVLDDLMEFYEGVIGYPEIDLRLAGEEAWLKGVNPELAEAVKKIIKTIRRYLEGSPYDGSEKPIPRYIIAEIFSQIAPEVQLLVNALDTEGKYGFLKHIKKLNLNSLAMLSKNYNENDKLWKELENEGYVYLE
What is the function of this protein?
Plays a role in the inhibition of global transcription by interacting with the RNA polymerase (RNAP) clamp, locking it in a fixed position and inhibiting the formation and/or stability of the pre-initiation complex (PIC) (PubMed:27882920).  Also overlaps with the transcription factor B binding site; overall RIP probably interferes with DNA loading onto RNAP but does not displace DNA once it is loaded (PubMed:34535646).  May play a role in virus particle assembly, possibly by dissociating active RNAP from the virus genome (Probable).
What are the official names of this protein?
RNAP inhibitory protein, RIP, ORF145.
What is the protein family that this protein belongs to?
Belongs to the viral ORF131/RIP family.
What are the subcellular locations of this protein?
Virion.
Protein: MAND_ECOL6
Sequence: MHHDKRCKESNMKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVASYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAANMPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYGMSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFDEHLLHDMHHRLTPIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLIEEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWVPNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGEKPGLGIEFDEKLAAKYPYEPAYLPVARLEDGTLWNW
What is the function of this protein?
Has low D-mannonate dehydratase activity (in vitro), suggesting that this is not a physiological substrate and that it has no significant role in D-mannonate degradation in vivo.  Has no detectable activity with a panel of 70 other acid sugars (in vitro).
What are the official names of this protein?
D-galactonate dehydratase family member RspA, D-mannonate dehydratase, Starvation sensing protein RspA homolog.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: COXX_STAAM
Sequence: MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLFGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAND_GEOSM
Sequence: MERKMLKSKIHRATVTGADLHYEGSITIDLDLMEASDIIPYEAVCIWDVTNGSRFETYAIEGERGSGVICINGAAARLVAPQDLVIIASFVNMENAEAIAHEPKLVFVDDKNRMLESRKEVAGQATLKSVHWKN
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSY_BUCBP
Sequence: MFKKRVFSWFGFKKNKTKINDLDDHIKKNNQDNLSQKKCNNICSQDSIAKSTKSDCCSENVANSSAVNESHSSSLMKLKLKQHVSHVNNKNSFLLTLTTKLVRTKEAFSIKLKNLFFKKKTYNSLLDDIEEQLLVSDIGVRTTRELVDSLIKVSTQHELKNLNLIIEILKSKMKKILNKVEGPLNINYKNLFVILVVGVNGVGKTTLIGKLAKNYKKKGKSVILAAGDTFRAAAIDQLKLWGEINSVSVITREIGSDPASVVYDAIKIAKLKCIDILIIDTAGRLHNKNNLMEELKKIKRVIHKIDSTISQETMLVLDACIGQNSIKQVKIFHESLNVTGLVITKLDSTAKGGVIFSIAQEFLIPVRYISFGEDFEDIQVFNSNIFVNAILSNNTLK
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).  Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: ARGI1_SCHPO
Sequence: MSPHKIPEVHRHIMSSRYMEGNAVSIINMPFSGGQPKDGAELAPEMIEAAGLPEDLERLGYSVNVVQNPKFKSRPLKEGPNQALMKNPLYVSNVTRQVRNIVQQELEKQRIAVNIGGDHSLAIGTVEGVQAVYDDACVLWIDAHADINTPDSSPSKNLHGCPLSFSLGYAEPLPEEFAWTRRVIEERRLAFIGLRDLDPMERAFLRERSITAYTMHDVDKYGIARVVEMALEHINPGRRRPIHLSFDVDACDPIVAPATGTRVPGGLTFREAMYICESVAETGSLVAVDVMEVNPLLGNKEEAKTTVDLARSIVRTCLGQTLL
What are the official names of this protein?
Arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: GLGA_DESVV
Sequence: MQRQVVFATSEMYPFSKSGGLGDVLGALPLALHRMGVPTAVVTPFYGRLRTADYPIRLTVSDCHVGYPWAPITCDVFEADYHGMPVYFIHRGEYFDRRYYYNDHKGDYFDNCERFVFFCRALLALMRRLGQPPAVLHAHDWQTALVPAFLYFLRQGDPFWQDTRSVLTIHNLAFQGRFASRLFETSGLPPQAWSVDGAEFWGDFNLLKAGIAYADKVTTVSPSYAREILGPAYGSGLDGILRKRAHALHGILNGADYDIWSPGNDRFLPCRYTPTDLAGKAQCKRALIEELGLDPHLARRPILGFIGRLRGQKGIDLLLDILPRLMESDVGVIILGEGNLTHEARALELMEAYRGRVCTIVSYTEDLAHRIQAGSDIFLMPSRYEPCGLTQMYALRYGTPPVATAVGGLRDTIVPWPSPESTGFTFGRCESAAFLRAILDAVHLWTTAPGDWQGMVRRAMAQAFTWERAGRAYLDLYAQLGVSPGEEGA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: ZN749_HUMAN
Sequence: MNLTEDCMVFEDVAIYFSQEEWGILNDAQRHLHSNVMLENFALLSSVGCWHGAKDEEVPSKQCVSVRVLQVTIPKPALSTLKAQPCKMCSSILKDILHLAEHDGTHPEQGLYTCAAEHDLHQKEQIREKLTRSDEWRPSFVNHSAHVGERNFTCTQGGKDFTASSDLLQQQVLNSGWKLYRDTQDGEAFQGEQNDFNSSQGGKDFCHQHGLFEHQKTHNGERPYEFSECGELFRYNSNLIKYQQNHAGERPYEGTEYGKTFIRKSNLVQHQKIHSEGFLSKRSDPIEHQEILSRPTPYECTQCGKAFLTQAHLVGHQKTHTGEQPYECNKCGKFFMYNSKLIRHQKVHTGERRYECSECGKLFMDSFTLGRHQRVHTGERPFECSICGKFFSHRSTLNMHQRVHAGKRLYKCSECGKAFSLKHNVVQHLKIHTGERPYECTECEKAFVRKSHLVQHQKIHTDAFSKRSDLIQHKRIDIRPRPYTCSECGKAFLTQAHLVGHQKIHTGERPYECTQCAKAFVRKSHLVQHEKIHTDAFSKRSDLIQHKRIDLRPRPYVCSECGKAFLTQAHLDGHQKIQTGERRYECNECGKFFLDSYKLVIHQRIHTGEKPYKCSKCGKFFRYRCTLSRHQKVHTGERPYECSECGKFFRDSYKLIIHQRVHTGEKPYECSNCGKFLRYRSTFIKHHKVCTGEKPHECSKCRELFRTKSSLIIHQQSHTGESPFKLRECGKDFNKCNTGQRQKTHTGERSYECGESSKVFKYNSSLIKHQIIHTGKRP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 749.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL16_NEIMA
Sequence: MLQPTRLKYRKQQKGRNTGIATRGNKVSFGEFGLKAVGRGRLTARQIEAARRAMTRHIKRGGRIWIRVFPDKPITEKPIQVRMGGGKGNVEYYIAEIKPGKVLYEMDGVPEELAREAFELAAAKLPIPTTFVVRQVGQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RS19_METM6
Sequence: MARQKKYSGKGGARKKNKQKQSVAPRRRVEFRYKGFTLEELQEMPIKKFMEIVPSRQRRTMLRGITPNQRKLVMKIKKARRLTNRGKEPRVIRTHCRDFVITPEMIGLTFGIYNGKEFKDVTLVEETVGRFLGEMAPTRAVVQHGSPGMGATRGSMFVPIK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL14_ENTFA
Sequence: MIQQESRLRVADNSGAREILTIKVLGGSGRKTANIGDVIVATVKQATPGGVVKKGEVVKAVIVRTKSGARRADGSYIKFDENAAVIIRDDKSPRGTRIFGPVARELRENNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: WDR6_HUMAN
Sequence: MDALEDYVWPRATSELILLPVTGLECVGDRLLAGEGPDVLVYSLDFGGHLRMIKRVQNLLGHYLIHGFRVRPEPNGDLDLEAMVAVFGSKGLRVVKISWGQGHFWELWRSGLWNMSDWIWDARWLEGNIALALGHNSVVLYDPVVGCILQEVPCTDRCTLSSACLIGDAWKELTIVAGAVSNQLLVWYPATALADNKPVAPDRRISGHVGIIFSMSYLESKGLLATASEDRSVRIWKVGDLRVPGGRVQNIGHCFGHSARVWQVKLLENYLISAGEDCVCLVWSHEGEILQAFRGHQGRGIRAIAAHERQAWVITGGDDSGIRLWHLVGRGYRGLGVSALCFKSRSRPGTLKAVTLAGSWRLLAVTDTGALYLYDVEVKCWEQLLEDKHFQSYCLLEAAPGPEGFGLCAMANGEGRVKVVPINTPTAAVDQTLFPGKVHSLSWALRGYEELLLLASGPGGVVACLEISAAPSGKAIFVKERCRYLLPPSKQRWHTCSAFLPPGDFLVCGDRRGSVLLFPSRPGLLKDPGVGGKARAGAGAPVVGSGSSGGGNAFTGLGPVSTLPSLHGKQGVTSVTCHGGYVYTTGRDGAYYQLFVRDGQLQPVLRQKSCRGMNWLAGLRIVPDGSMVILGFHANEFVVWNPRSHEKLHIVNCGGGHRSWAFSDTEAAMAFAYLKDGDVMLYRALGGCTRPHVILREGLHGREITCVKRVGTITLGPEYGVPSFMQPDDLEPGSEGPDLTDIVITCSEDTTVCVLALPTTTGSAHALTAVCNHISSVRAVAVWGIGTPGGPQDPQPGLTAHVVSAGGRAEMHCFSIMVTPDPSTPSRLACHVMHLSSHRLDEYWDRQRNRHRMVKVDPETRYMSLAVCELDQPGLGPLVAAACSDGAVRLFLLQDSGRILQLLAETFHHKRCVLKVHSFTHEAPNQRRRLLLCSAATDGSLAFWDLTTMLDHDSTVLEPPVDPGLPYRLGTPSLTLQAHSCGINSLHTLPTREGHHLVASGSEDGSLHVFVLAVEMLQLEEAVGEAGLVPQLRVLEEYSVPCAHAAHVTGLKILSPSIMVSASIDQRLTFWRLGHGEPTFMNSTVFHVPDVADMDCWPVSPEFGHRCALGGQGLEVYNWYD
What is the function of this protein?
Enhances the STK11/LKB1-induced cell growth suppression activity.  Negative regulator of amino acid starvation-induced autophagy.
What are the official names of this protein?
WD repeat-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR6 family.
Protein: SERC_THIDA
Sequence: MTIYNFSAGPAVLPKDVLQQVQAELVDWHGSGMSVMEMSHRGKEFMGIAAEAEADLRELMAIPANYKVLFLQGGASSQFAMVPMNLLRGKASADYLNTGEWSKKAIKEAKKYAAVNVVASSEDRNFSYAPTQDRWKLDPNAAYVHYTPNETIGGVEIFWTPEAGDVPIAADMSSTILSRPIDVSKYGVIYAGAQKNIGPAGLTIVIVREDLMGETVAGTPTMFDYKIHADNESMYNTPATFAMYTAGLVFKWLKARGGLAGMEKINREKAALLYEALDATDFYASPVAKDNRSLMNVPFTLKDAALDEAFLKGAKERGLLQLKGHRSVGGMRASIYNAMPTEGVKALVDYLHAFEKNHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_SULAC
Sequence: MIDISGKDIVLREAIAEGFIKLKKDTIEKITKREIEKGDVIATAKVAGILAAKKTHELLPMCHPIPLEYINVEIEIENDGLKVVSTVRAHYRTGVEMEALTATSIALLTIWDMVKKYEKDEEGQYPLTEISKIRVVSKIKSYG
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Probable cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: YIDC_YERPE
Sequence: MDSQRNLLLIALLFVSFMIWQAWQVDNNPQPTAQTTQQTTNTATGDKASQAVPGSGQGQLITVKTDVLSLTINTRGGDIEQANLLAYPDTLGSSNTFELLETTPSFVYQAQSGLTGKNGPDNPANGDRPLFEVPQTSFVLADGQDELRIPLTFTSKDGSVFIKTFVLKRNDYAIGVDYHVNNASAAPLELTLFGQLKQSINLPKKRDTGSNNFALQTYRGAAYSSDETKYKKYSFSDIEDKNLDITTKGGWVAMLQQYFATAWIPAANETNTFYSAELGNGLAAIGFKGAPVVIQPGEQKQLSATLWVGPEIQNKMAEIAPHLDLTVDYGWLWFISQPLFKLLKFIHSFVGNWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRLLQPKLAAMRERIGDDKQRMSQEMMALYKAEKVNPLGGCLPLIIQMPIFLALYYMLMSSVELRHAPFILWIHDLSAQDPYYILPILMGITMYFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPAGLVLYYIVSNLVTILQQQLIYRGLEKRGLHSREKKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NIP42_ARATH
Sequence: MTSHGEEIEDEQISRIEKGNCKDSQGGMETAICSSPSIVCLTQKLIAEMIGTYFIIFSGCGVVVVNVLYGGTITFPGICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAVFRRFPWYQVPLYIGAQLTGSLLASLTLRLMFNVTPKAFFGTTPTDSSGQALVAEIIISFLLMFVISGVATDSRATGELAGIAVGMTIILNVFVAGPISGASMNPARSLGPAIVMGRYKGIWVYIVGPFVGIFAGGFVYNFMRFTDKPLRELTKSASFLRSVAQKDNASKSDG
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Probable aquaporin NIP4-2, NOD26-like intrinsic protein 4-2, AtNIP4;2, Nodulin-26-like major intrinsic protein 5, NodLikeMip5, Protein NLM5.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.