PharMolix/UniProtQA huggingface dataset:
Protein: 3L21_NAJNA
Sequence: IRCFITPDITSKDCPNGHVCYTKTWCDGFCSIRGKRVDLGCAATCPTVRTGVDIQCCSTDDCDPFPTRKRP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 1, Toxin A.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MDHM_EUCGU
Sequence: MRASMLRLIRSRSSSAAPRPHLLRRAYGSESVPERKVAVLGAAGGIGQPLALLMKLNPLVSQLALYDIAGTPGVAADVGHINTRSEVAGYVGEEQLGQALEGSDVVIIPAGVPRKPGMTRDDLFNINAGIVKSLCTAIAKYCPNAVVNMISNPVNSTVPIAAEIFKKAGTYNEKKLLGVTTLDVVRAKTFYAGKAKVPVEEVNVPVVGGHAGITILPLFSQAVPKANLADEDIKALTKRTQDGGTEVVEAKAGKGSATLSMAYAGALFADACLKGLNGVPDVVECSFVQSSIITELPFFASKVKLGKNGVEEVLELGPMSDYEKQGLEILIPELKASIEKGIKFANQ
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: EXP26_ARATH
Sequence: MKLLEKMIYVEFLMIIMAMWVVPMSYGHGAMIGNAVEAPDVAEAPGINDPSKALDPNWYDARATFYGDIHGGDTQQGACGYGNLFRQGYGLATAALSTALFNDGYTCGACYEIMCTRDPQWCLPGSVKITATNFCPANYSKTTDLWCNPPQKHFDLSLAMFLKIAKYKAGVVPVRYRRIPCSKTGGVKFETKGNPYFLMVLIYNVGGAGDIKYVQVKENKTGWITMKKNWGQNWTTSTVLTGQGLSFRVTTTDGITKDFWNVMPKNWGFGQTFDGKINF
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Putative expansin-A26, AtEXPA26, Alpha-expansin-26, At-EXP26, AtEx26, Ath-ExpAlpha-1.16.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: CAPSD_HV19S
Sequence: MSHTTITNFLAGVIARPQGGNITSDETFRRYRTIVRTSATIGGNEDSRTTSIFHEIGRAVNTKGKALAVAGMEAPLVEASYPTNAVLVEDFIGLAKKYTNFSATFEYSSLAGVVERLARGLAACSVFEDVTSTDLRGNNPLAVHALATYDGPVNSLTSAVFIPRLVNNALTGDVFAVLCNCVAGEGGTVVTDTIELDANTRQPIVPEVGPLGVPGAIVDALRLLGSNMIASDQGPLFALALTRGIHRVLSVVGHTDEGGIVRDLLRCGGFGLPFGGIHYGLEEYSGLPALQFNSAAATAAYVDGIALVTAAVVAHADPGERYNGEWFPTFFDGTTHADTMRRSGDSTEGTAAMADRNRAQLLARQQLFWRPYITALGACFSTAGDISVAERFQCAASHSLGADPRHLRLPSVAPYFWIEPTGLIPHDFLGSVAEEEGFASYCWRDTTRTRPAWDSIVLSGARDTTFSAYHIRMKGARTAWFLAHWLGHPENGLGATRVRQLDPNAVLHPGPCEGNEQVRDRVEADLPLTDYLWRRGQSPFPAAGELLNLTSEWGILFRHVTFTDDGDLNPEHLPAAHEMADTTVTMTVGRPIGIAPGRSNAGDNQARRARTRASVELSAASRRARVFGRPDVGEMPTLTSAPAPIPASPAYDGNRGGEAGGVTGRGNNRSAAPGHASWSERQADGVPVNVTPHHNALRAPPFPRQQGALGGGGNVPLPPAPGAAPPPPPGPPNGPPAGPPPSDDGSSNPAAPVPTAIHAPPAAAQADRAEGQ
What is the function of this protein?
Binds and removes 5' cap structures from cellular mRNA.
What are the official names of this protein?
Major capsid protein, Major coat protein.
What is the protein family that this protein belongs to?
Belongs to the totivirus major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RTX11_ACTPL
Sequence: MANSQLDRVKGLIDSLNQHTKSAAKSGAGALKNGLGQVKQAGQKLILYIPKDYQASTGSSLNDLVKAAEALGIEVHRSEKNGTALAKELFGTTEKLLGFSERGIALFAPQFDKLLNKNQKLSKSLGGSSEALGQRLNKTQTALSALQSFLGTAIAGMDLDSLLRRRRNGEDVSGSELAKAGVDLAAQLVDNIASATGTVDAFAEQLGKLAMPYLTLALSGLASKLNNLPDLSLAGPGFDAVSGILSVVSASFILSNKDADAGTKAAAGIEISTKILGNIGKAVSQYIIAQRVAAGLSTTAATGGLIGSVVALAISPLSFLNVADKFERAKQLEQYSERFKKFGYEGDSLLASFYRETGAIEAALTTINSVLSARSAGVGAAATGSLVGAPVAALVSAITGIISGILDASKQAIFERVATKLANKIDEWEKKHGKNYFENGYDARHSAFLEDTFELLSQYNKEYSVERVVAITQQRWDVNIGELAGITRKGSDTKSGKAYVDFFEEGKLLEKEPDRFDKKVFDPLEGKIDLSSINKTTLLKFVTPVFTAGEEIRERKQTGKYQYMTELFVKGKEKWVVTGVQSHNAIYDYTNLIQLAIDKKGEKRQVTIESHLGEKNDRIYLSSGSSIVYAGNGHDVAYYDKTDTGYLTFDGQSAQKAGEYIVTKELKADVKVLKEVVKTQDISVGKTCSEKLEYRDYELSPFELGNGIRAKDELHSVEEIIGSNRKDKFFGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGGDGDDELQVFEGQYNVLLGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDIYRYSKEYGRHIIIEKGGDDDTLLLSDLSFKDVGFIRIGDDLLVNKRIGGTLYYHEDYNGNALTIKDWFKEGKEGQNNKIEKIVDKDGAYVLSQYLTELTAPGRGINYFNGLEEKLYYGEGYNALPQLRKDIEQIISSTGAFTGDHGKVSVGSGGPLVYNNSANNVANSLSYSLAQAA
What is the function of this protein?
One of the virulence factors of A. pleuropneumoniae, which has a strong hemolytic activity and is cytotoxic for alveolar macrophages and neutrophils.
What are the official names of this protein?
RTX-I toxin determinant A from serotypes 1/9, APX-IA, ApxI, Cytolysin IA, CLY-IA, Hemolysin IA, HLY-IA.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein.
Protein: RS17_RHOPT
Sequence: MPKRTLQGVVVSDKQAKTIVVRVDRRFTHPIYKKTIRRSKNYHAHDENNQFKPGDMVWIEESKPISKLKRWTVVRGEPKKTA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DNAE2_AROAE
Sequence: MDSAPPSPSPSPAPAYAELHCLTNFSFQRGASHPEELVARAAEAGYTALAITDECSLAGVVRAHQQLRRLARPLKLLIGSELRLVDGLRVVLLATDRAAYGRLARLITIGRRAATKGRYQLTCADLDRGIPGCLALVVPPDDRILDAAALVADARWVGERFPDAAWLAVELACGPDDGRRLEALLAIASAAGLPPVAATGALMHDPSRRALADVLAALRLRVTIAEAGRALAPNAERALHERAVLARRYPAELLAETLRIVARCHFRLDELRYEYPAELVPDGETPASWLRRLVEDGLRWRHGRPQDDLAPPKVRAQVEHELALIAELGFEAYFLTVEDLVRFARGRGILCQGRGSAANSVICWALGITEVDPELGIMLVERFISKERDEPPDIDVDFEHERREEVIQYVYRKYGRERAALAATVIRYRARSALRDVGRALGLPPGQLERLARDRFWFDAGRIRPERLREAGFDPASPGVQRLATLTEALVGFPRHLSQHVGGFVIARGRLDELVPVENAAMPERTVIQWDKDDLDALGLLKIDVLALGMLSALRRSLALVSTWRGRPFTLADIPREAPEVYRMLSEADSIGVFQIESRAQMTMLPRLKPARFYDLVVQVAIVRPGPIQGGMVHPYLQARARIERDEPVSYPQPHCPDADADGTCVPRPDDVRRVLERTLGVPIFQEQVMQLAVVAAGFTPGEADQLRRAMGAFRRHGELERYRAKLLAGMAARGYRAEFAERLCDQIEGFGSYGFPESHAASFALLVYCSAWLKCCEPAAFLCGLLNSQPMGFYAPSQLIQDARRHGVVVLGAEVTASDWDCTLEALPDASPGAAPAVRLGLQLVKGFGREAAMRIVAARTERPFPNVDELALRARLDAAALKRLAEAGALEPLAGHRRQALWQAAAGHAPEGVLRGARIAEPRAELAAPSEAQELVADYARLGFTLGRHPLALLRAKLTTLRFVTAAEIRDYPDRKLARIAGLVTCRQRPGTAKGTLFLTVEDETGLANVIVQAELVERQRREVLGARLLGVFGQIRSKGQVVHLLAQRLVDHSALLGALEARSRDFQ
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALR_SALTS
Sequence: MATIKDVARLAGVSVATVSRVINDSPKASEASRLAVTSAMESLSYHPNANARALAQQATETLGLVVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQKERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQIPGMVLINRILPGLEHRCVALDDRYGAWLATRHLIQQGHTRIGYICSNHTISDAEDRLRGYYDALAESHIPANDRLVTFGEPDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGVGVPGEVSLIGFDDVLVSRYVRPRLTTIRYPIVTMATQAAELALALAGKCPTPEVTHVFSPTLVRRHSVSTPTDTGHLSTTD
What is the function of this protein?
Repressor of the galactose operon.  Binds galactose as an inducer (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator GalR, Galactose operon repressor.
Protein: RNF13_BOVIN
Sequence: MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVRDNSSGTFIVLIRRLDCNFDEKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHIILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENEVSEHTPLLRPLASASTQSFGALSESRSHQNMTESSDYEEDDNDTDSSDAENEINEHSVVVQLQPNGERDYNIANTV
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates cell proliferation.  Involved in apoptosis regulation.  Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA.  Also involved in protein trafficking and localization.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF13, RING finger protein 13.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Nucleus inner membrane; Single-pass type I membrane protein. Note=Under certain conditions, relocalizes to recycling endosomes and to the inner nuclear membrane.
Protein: RS9_BURVG
Sequence: MIGNWNYGTGRRKSAVARVFIKAGKGDIIVNGKPIADYFSRETSLMIVRQPLELTNHGQTFDIKVNVNGGGETGQAGAVRHGITRALIDYDATLKPSLSNAGFVTRDAREVERKKVGLRKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: Y0931_DICDI
Sequence: MSIYSKFTINDVLLNKESLQKKNKYTCPICFELIYKKSIYQCSSGHYACQECWEKSLEIKQECMICRCKVKSFKNLSRCLVIEQNFSKKECNCIYSFHLDYFIDGANQENEDEENEDEENEDDEDENEDEENGEDDEDKDEDEENENENEENKDEENEKRKLIKDEENGCKEIINVDQLDRHIQNCKFKFVKCSHIGCDRVLRLNSLKEHENQCGFKLVKCEYCACDGIIQVQLENHYDECPKFVIGCPQGCLNFFERDQIKSHIENDCNNSTIQCKYYEYGCKVEMKRSELQRHLENVNHQLFMGKLIDKLSSTLDQSMKIQELLLKEIEKSKITCSELQRKNDELSSLITEIDDNYFNKNDFINSWKLTSQGYTNKWIISNYSNLVENTPHPEYIYSPSFDIVSREFVISIYPNGSLTGKDHLSLFLHNNNEDPNKLEFTLELVNLLDKSKSITRKGLEVFEEIERKGWSKFLASKLINKKNGWLSDDDKLTINIYVKILYDDIEPLES
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0290931.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_CITBB
Sequence: MSEMTPMMRQFLEIKAEHPDAILFFRCGDFYEMFLDDAVKASRILGITLTSRNKNADGSEVPLCGVPYHSCAPYIAKLVEAGEKVAICEQAEDPKQAKGIVKREVVKVITPGLVIEDASLSPKENNYLLALCCDGECYGLSYLDLSTGEFRVTELDGLQAALAELTCIGPREIILPVSFREEPKRKEVAHVIVDRSITYFEEWVYDPDYCKRLVANQFKGATAESLGCDRLPIALLAAGAVLHYLVDTQKGHAPHVTGITPYNENEHLLLDESTRRNLELTATLSEGKRKGSLLGLMDRTVTAMGGRKLKQWINYPLMDLKKIWLRQDAIQELMEAPGTREAMKSLLAGVYDLERLNGRISLASASAKDLSALRSSLSRLPAIKEQVAACGAGLLKELNAGIDPLDELCDLISRAIVDDPPFVLRDGGIIADGYNQELDELRAISREGKGFIARLEAQEKGRTGISSLKIRYNKVFGYYIEVTKANVSAIPDDYIRRQTLANAERYITPELKEYEEKVLGAEDRIKDLEFSLFQEVREAAAAQGERIARTADRLACLDVLASLSELAHDKGYCRPEVHEGSELSITEGRHPVIDDMHSSERFVPNDTLLDNGENQLIIITGPNMAGKSTFMRQVALISLMAQMGSFVPADKALIPLVDRIFTRVGASDNLARGTSTFDGVSIAWAVAEFLHDNKMHAAKTLFATHYHELTELAVTRPGIKNFNIAVREWNERIIFLRKIVPGGASHSYGIQVARLAGLPQAVIERAKEILVNLEKGEYGEGGVPRLARGKKVPPPSPQLSLFGAGDDQIRERLKEVEVALLTPLEALNLVDELKRMI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DBHA_BURP2
Sequence: MNKQELIDAVAAQTGASKAQTGETLDTLLEVIKKAVSKGDSVQLIGFGSFGSGKRAARTGRNPKTGETIKIPAAKTVKFTAGKAFKDAVNKR
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DEF_STRPC
Sequence: MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDILLGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKEAYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQHRIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: UBAD1_HUMAN
Sequence: MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSAFFQETNIPYSHHHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHSGGSGSPMAATATSPPPHFPHAATSSSAASSWPTAASPPGGPQHHQPQPPLWTPTPPSPASDWPPLAPQQATSEPRAHPAMEAER
What are the official names of this protein?
UBA-like domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the UBALD family.
Protein: GLT10_MOUSE
Sequence: MRRKEKRLLQAVALALAALVLLPNVGLWALYRERQPDGSPGGLGAAVAPAAVQELHSRQKKTFFLGAEQRLKDWHNKEAIRRDAQRVGYGEQGKPYPMTDAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIRTRMLGASAATGDVVTFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVVAQKKLRVSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCTDTKLGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRVFMNTCNPSSLTQQWLFEHTNSTVLENFNKN
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.  Has activity toward Muc5Ac and EA2 peptide substrates (By similarity).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 10, Polypeptide GalNAc transferase 10, GalNAc-T10, pp-GaNTase 10, Protein-UDP acetylgalactosaminyltransferase 10, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PTH_RHILW
Sequence: MLIIAGLGNPGGKYAGNRHNIGFMAVDAIHRRHSFSPWSKKFRAEIAEGELGGEKVLLIKPQTFMNLSGEAVGEAMRFYKLQPADLVAIYDELDLPAGKARLKTGGGHGGHNGIKSLDAHCGKEYRRLRLGIGHPGIKEMVQNHVLGDFAKADKAWLEPLLDTLADNADMLVRNEDSQLMNKIALALGGKAEEEKPRKDNKTTEKKPAGQSHIHQARNHNQPKVLTTGPMADILKKMFGNKGE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1586_KLEP3
Sequence: MSKSLTIIWQYLRAFVLIYACLYAGIFIAGLLPITIPGSIIGMLILFVLLALQIMPPQWVNPGCNILIRYMALLFVPIGVGVMQYWDLLRAQLGPVVISCAISTLVVFVVVSWSSHLVHGERKVIGQKEKKNDA
What are the official names of this protein?
UPF0299 membrane protein KPK_1586.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THII_SULAC
Sequence: MPLIALTPSGEIAIKSSRSRRRFERILIKNIGKVIRVKSYKLDQGIIILNTDDDYSKLSKVFGISKYFEVYEFSFSSIQDIVNFVKDRFNQTVKGKKFAVKVKRVGNHSFNSMDVAREIGNALYPYSLGVDLENPDVKINLILRQDYGYVYTTENDGPRGFPVGSTGKTVVLFSGGFDSPVATWMLMKRGVRPILLNFELGGKVQRDLVLKEVDVLKQWSSNNDINVYFINGLDVTSKLVNAEPSLRILLLKRIMYNTARVLANKLRAYSITTGESLSQVSSQTMINLYVTEYDIDLPVFRPLIGFDKEEIIQMSRKIGTFEYSSKLPEYCVISNKSIVKSQLDKVLEEERKIEINYEELIKKAELVRI
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_FERNB
Sequence: MRIGILTIFPDFVKVIKEYGVIAQAVENNLLQIDIFNLRDFTTDKHKVVDDYAYGGGPGMVMKPEPFFKFFEYYNQMFGKPYVVLTSPQGKTLNNEIAKKLSAQERLLIICGRYEGIDERVMKFVDEEISIGDYVLTGGELPAMVITDVVSRFIPGVVEEESVKNDSFYNDLLDHPHYTRPRNIDGLEVPEVLLSGNHEEIELWRRKESLRKTISKRPDLFLKHQFDEVDKKALLLLFKELIKDAK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_OPITP
Sequence: MSTTVVKPEIIAQYKTHDKDTGSSEVQVALLTARINHLTEHLRTHRKDFHSRRGLLQMASRRRKLLDYLKKHDLPKYTELLQKLNLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TO202_ARATH
Sequence: MEFSTADFERLIMFEHARKNSEAQYKNDPLDSENLLKWGGALLELSQFQPIPEAKLMLNDAISKLEEALTINPGKHQALWCIANAYTAHAFYVHDPEEAKEHFDKATEYFQRAENEDPGNDTYRKSLDSSLKAPELHMQFMNQGMGQQILGGGGGGGGGGMASSNVSQSSKKKKRNTEFTYDVCGWIILACGIVAWVGMAKSLGPPPPAR
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM20-2, Translocase of outer membrane 20 kDa subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: YAJQ_ECO5E
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: TPIS_SECCE
Sequence: MGRKFFVGGNWKCNGTVSQVETIVNTLNAGQIASPDVVEVVVSPPYVFLPTVKDKLRPEIQVAAQNCWVKKGGAFTGEVSAEMLVNLGIPWVILGHSERRSLLAESSEFVGEKVAYALAQGLKVIACVGETLEQREAGSTMEVVAEQTKAIADKIKDWTNVVVAYEPVWAIGTGKVASPAQAQEVHANLRDWLKTNVSPEVAESTRIIYGGSVTGASCKELAAQPDVDGFLVGGASLKPEFIDIINAATVKSA
What are the official names of this protein?
Triosephosphate isomerase, cytosolic, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_ESCF3
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGICYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: KDPA_LEPIC
Sequence: MVTEWIQLLIFLFALLIFSPLFGLGLYKVYLYKTSGFEKFLYKICGIDPNRNMDWKEYALSLLVFNFFGFLLLFLILFFQNYLPLNPENFPGLVWDLAFNTAVSFTTNTNWQAYSGESTLSFFSQMAGLTTQNFLSATTGLCVLLALSRGISVNYNVFALGNFWKDMIRGTLYVLLPLSFIFALFLVGFGVVQTFSESVSAITLEGNTQIIPLGPVASQVAIKQLGTNGGGYFGVNASHPFENPSPISNFLQMFSILILPGACVFLYGRITGSIRHAWAIFSVMFTILCVGILIVWTFESSWNPISGTLGFWEGKEIRFGILNSSIWEVATTVASNGSVNSMHDSFSPIGGLVGILNIQLGEIVFGGVGAGMYGMILFVLLTVFLSGIMVGRSPEYLGKKIEKREIQMSILGILLPSTIILLFTAISVSVSDALSSLTNRGPHGLSEILYAFSSGAGNNGSAFAGLNANTTYYNVMIAIAMILGRFGVILPVLVIAGSLAQKKRSEIVSEGSFSTEGGTFYILLLSVIIIVGALTFFPVLTIGPILEHFIMFQNLTF
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL6_PSESM
Sequence: MSRVAKNPVKLPSGVEVKLVGQQLSVKGAKGTLELIIHSSVEIVEEAGELRFAARNGDQQTRAMAGTTRALVNNMVQGVSQGFERKLQLVGVGYKAQAKGTVLNLALGFSHPVDYELPNGITAETPSQTDILIRGIDKQLVGQVAAEIRDFRRPEPYKGKGVRYADEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TYW5_MOUSE
Sequence: MAEQRLPVPRLRGVSREQFMEHLYPQRKPLVLEGLDLGSCTSKWTVDYLSQVGGTKEVKIHVAAVPQMDFISKNFVYRTLPFNKLVQRAAEETHKEFFISEDEKYYLRSLGEDPRKDVADIRQQFPSLGGDITFPMFFREEQFFSSVFRISSPGLQLWTHYDVMDNFLIQVTGKKRITLFNPRDAQYLYLSGSKSEVLNIDSPDLDKYPLFPKARRYECSLEAGDVLFIPALWFHNVVSEEFGVGVNIFWKHLPSECYDTTDTYGNKDPVAASRAVQILDRALKTLAELPEEYRDFYARQMVLRIQDKAYSKNFE
What is the function of this protein?
tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*).  OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4.  OHyW is a derivative of wybutosine found in higher eukaryotes.
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 5, tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the TYW5 family.
Protein: ECPB_ECOLI
Sequence: MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIKNSTDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTPASLLLPAQASEVIRFFYKGPADEKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLTNTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKFIPVK
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity).
What are the official names of this protein?
Probable fimbrial chaperone EcpB.
What is the protein family that this protein belongs to?
Belongs to the EcpB/EcpE family.