PharMolix/UniProtQA huggingface dataset:
Protein: KI13A_HUMAN
Sequence: MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKVPEAKRLYGKRGDPFYEAQENHNLIGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMRVTGAVPERVVEDDSSENSSESGSLEVVDSSGEIIHRVKKLTCRVKIKEATGLPLNLSNFVFCQYTFWDQCESTVAAPVVDPEVPSPQSKDAQYTVTFSHCKDYVVNVTEEFLEFISDGALAIEVWGHRCAGNGSSIWEVDSLHAKTRTLHDRWNEVTRRIEMWISILELNELGEYAAVELHQAKDVNTGGIFQLRQGHSRRVQVTVKPVQHSGTLPLMVEAILSVSIGCVTARSTKLQRGLDSYQRDDEDGDDMDSYQEEDLNCVRERWSDALIKRREYLDEQIKKVSNKTEKTEDDVEREAQLVEQWVGLTEERNAVLVPAPGSGIPGAPADWIPPPGMETHIPVLFLDLNADDLSANEQLVGPHASGVNSILPKEHGSQFFYLPIIKHSDDEVSATASWDSSVHDSVHLNRVTPQNERIYLIVKTTVQLSHPAAMELVLRKRIAANIYNKQSFTQSLKRRISLKNIFYSCGVTYEIVSNIPKATEEIEDRETLALLAARSENEGTSDGETYIEKYTRGVLQVENILSLERLRQAVTVKEALSTKARHIRRSLSTPNVHNVSSSRPDLSGFDEDDKGWPENQLDMSDYSSSYQDVACYGTLPRDSPRRNKEGCTSETPHALTVSPFKAFSPQPPKFFKPLMPVKEEHKKRIALEARPLLSQESMPPPQAHNPGCIVPSGSNGSSMPVEHNSKREKKIDSEEEENELEAINRKLISSQPYVPVEFADFSVYNASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDADSTEHSTPSLVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNILEDHSFTEFMGVSEGKDFDGLTDSSAGELSSRRSLPNKTGGKTVSDGLHHPSQLHSKLENDQVIIPEAAFWVLCCQ
What is the function of this protein?
Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis.  Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex.  During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes.  Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.
What are the official names of this protein?
Kinesin-like protein KIF13A, Kinesin-like protein RBKIN.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Note=Recruited to the midbody during cytokinesis.
Protein: DXS_CUTAK
Sequence: MPRMALLDDIGCPDDVRKLTTKQAEDLAEEIRAFLIDKVSRTGGHLGPNLGVVELTIALHRVFDSPHDPIIFDTGHQSYVHKILTGRANGFEKLRQRGGLSGYPSRAESVHDWVENSHASASLSWAEGMAKGFLSQGEDRTVVAVIGDGALTGGMAWEALNSIADQQGLRLVIVVNDNGRSYTPTVGGLANQLAIIRTDPHYEEALDRMKRHVTDKPLGKQVFGLMHAAKAGVKDALIGNGIFSDLGIKYLGPVDGHDVLSVERALELAKRYGHPVIVHVMTTKGKGFAAAEANEEDHFHAVGRIDPVTGASLKASGGASWTQAFAGAMVELGERRPDIVGVTAAMLHPVGLAPFAARHPDRVLDVGIAEQHAVTSAAGMAAAGLHPVVALYSTFLNRAFDQLLMDAGLHHAGVTIVLDRAGITGTDGASHNGMWDMAMCGIVPGLMLSAPRDRQHLVSVLNEAVDIDDRPTVIRYSKDPIPDDIRIVTSHDGLDVLCDGPEDGILLVAHGQLCAEALAAVDQLDSPVRVVSPRWSLPVCGGLIEEAARARAVVSVEDGLVVSGLGSHLADALSQRGMWRPIRSLGIPQRYLDHDSRSAIMAELGLDSRGIADAVSQLVAQLDGEYS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RS21_SYNPW
Sequence: MTQVTVGENEGIESALRRFKRQVSKAGIFADLKRLRHHETPIEKYKRKAQQRRRRR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CITG_SHIF8
Sequence: MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNSRLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMATNGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPTDLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: RL1_HELP2
Sequence: MAKKVFKRLEKLFSKIQNDKAYGVEQGVEVVKSLASAKFDETVEVALRLGVDPRHADQMVRGAVVLPHGTGKKVRVAVFAKDIKQDEAKNAGADVVGGDDLAEEIKNGRIDFDMVIATPDMMAVVGKVGRILGPKGLMPNPKTGTVTMDIAKAVSNAKSGQVNFRVDKKGNVHAPIGKASFPEEKIKENMLELVKTINRLKPSSAKGKYIRNAALSLTMSPSVSLDAQELMDIK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TMM18_MOUSE
Sequence: MSSAYSVRSFPVSIPAVIMETDWTEPWLLGLLAFHLLCLLLTCFSSQRYKLQIGHFLCLVVLVYSAEYINEVAAVNWRLFSKYQYFDSRGMFISLVFSAPLLFNAMLIVIMWVRKTLTVMTDLKTLQEERKERRRRRKEE
What is the function of this protein?
Transcription repressor.  Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats.  Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC) (By similarity).
What are the official names of this protein?
Transmembrane protein 18.
What is the protein family that this protein belongs to?
Belongs to the TMEM18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus membrane; Multi-pass membrane protein.
Protein: GPAT3_RAT
Sequence: MEGTDLVVKLLSTWLTLVGSLILLPSAFGLSLGISEIYMKILVKTLEWATLRIEKGAPKESVLKSPASMGIIQRDESPMEKGLSGLRGRDFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFHYISPKLTIVWVLGVLVRYCFLLPLRVTLAFIGISLLIIGTTLVGQLPDSSLKNWLSELVHLTCCRICVRSLSGTIHYHNKQYRPQKGGICVANHTSPIDVLILATDGCYAMVGQVHGGLMGIIQRAMVKACPHVWFERSEIKDRHLVTKRLKEHIADKKKLPILIFPEGTCINNTSVMMFKKGSFEIGGTIYPVAIKYNPQFGDAFWNSSKYNLVSYLLRIMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQGGLTELPWDGGLKRAKVKDTFKEEQQKTYSKMIVGNGSPSLALDSSTVDNHGSPEPAFRSESL
What is the function of this protein?
Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone.  Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.  Protects cells against lipotoxicity.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 3, GPAT-3, 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10, AGPAT 10, 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9, 1-AGP acyltransferase 9, 1-AGPAT 9, Lysophosphatidic acid acyltransferase theta, LPAAT-theta.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SMG_VIBPA
Sequence: MMMDILMYLFETYIHSDAELQVEQDELEEELLRAGFQQKDIYKALVWLEELAALQQSDTSSAISACIASSSTRIYTAKEMQRLDLECRGFLLFLEQINVLTTETREMVIDRVMGLETSEFELEDLKWIILMVLFNVPGNENAYTLMEELLYTKEQGILH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RMI1_BOVIN
Sequence: MSVTSIALRVETWLSATWHVKVPVTWLEACINWIQEENDHVNLSQAQMNKQVFEQWLLTDLRDLEHRLLPSGILETPKGELNGFFALQINSLVDVSQPAYAQIQKLRGKNTTNDLITAETQVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQSIPALHSDLPPGTKILIYGNISFRLGVLLLKPENVKMLGGEVDALLEEYAQEKVLARLIGEPDPIVSVIPNNSNQIIPRITDVLDPALGPSDEELLASLDENDELAANNNTSLERSCFIGNSSNTVPIRQSDFETELVISPRPREKPRNQSMLFTDEELDDFSLEEALLLEEAVQKEQMETKELQLLTLNRTTDESIEKFSHRSNTLNNFSFICKNGNNNWSEKNLSEQMTSEDKSLSCPSTRDQNSSSLSVNHNVPLPHDFTNKGKSSETYKIKQISSSDGHSLNNKMFNGELVSNVPKRSSDVPNENEHHLQTCSLQLSENSTGLPITMDLYSPPFIYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSVRAKISDGTAYLDVDFVDEILTSLIGFSVSEMKRLKKDPCKYQKFLEGLQKCQRELIDLCCLMTISFNPSLSKAMVLALQDVNTDHLENLKRRLKK
What is the function of this protein?
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells.  Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution.  Required for BLM phosphorylation during mitosis.  Within the BLM complex, required for BLM and TOP3A stability (By similarity).
What are the official names of this protein?
RecQ-mediated genome instability protein 1.
What is the protein family that this protein belongs to?
Belongs to the RMI1 family.
What are the subcellular locations of this protein?
Nucleus. Note=Forms foci in response to DNA damage.
Protein: AB5G_ARATH
Sequence: MEKQGCEIEALDIDYNIFVRKINVNPFGIFRRKPRPEADQPVKTEEESLKLEDETGNKVKHVLKGVTCRAKPWEILAIVGPSGAGKSSLLEILAARLIPQTGSVYVNKRPVDRANFKKISGYVTQKDTLFPLLTVEETLLFSAKLRLKLPADELRSRVKSLVHELGLEAVATARVGDDSVRGISGGERRRVSIGVEVIHDPKVLILDEPTSGLDSTSALLIIDMLKHMAETRGRTIILTIHQPGFRIVKQFNSVLLLANGSTLKQGSVDQLGVYLRSNGLHPPLHENIVEFAIESIESITKQQRLQESRRAAHVLTPQTTLQEKRSEDSQGESKSGKFTLQQLFQQTRVADVGTMNIATEFTRDFANSRLEETMILTHRFSKNIFRTKELFACRTVQMLGSGIVLGLIFHNLKDDLKGARERVGLFAFILTFLLTSTIEALPIFLQEREILMKETSSGSYRVSSYAVANGLVYLPFLLILAILFSTPVYWLVGLNPSFMAFLHFSLLIWLILYTANSVVVCFSALVPNFIVGNSVISGVMGSFFLFSGYFISNHEIPGYWIFMHYISLFKYPFEGFLINEFSKSNKCLEYGFGKCLVTEEDLLKEERYGEESRWRNVVIMLCFVLLYRFISYVILRCRCSQRSFKTTLA
What are the official names of this protein?
ABC transporter G family member 5, ABC transporter ABCG.5, AtABCG5, White-brown complex homolog protein 5, AtWBC5.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UMAA_MYCTU
Sequence: MTELRPFYEESQSIYDVSDEFFSLFLDPTMAYTCAYFEREDMTLEEAQNAKFDLALDKLHLEPGMTLLDIGCGWGGGLQRAIENYDVNVIGITLSRNQFEYSKAKLAKIPTERSVQVRLQGWDEFTDKVDRIVSIGAFEAFKMERYAAFFERSYDILPDDGRMLLHTILTYTQKQMHEMGVKVTMSDVRFMKFIGEEIFPGGQLPAQEDIFKFAQAADFSVEKVQLLQQHYARTLNIWAANLEANKDRAIALQSEEIYNKYMHYLTGCEHFFRKGISNVGQFTLTK
What is the function of this protein?
Methyltransferase that modifies short-chain fatty acids.  In vitro, catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (SAM) to the double bond of phospholipid-linked oleic acid to produce tuberculostearic acid (10-methylstearic-acid or TSA).
What are the official names of this protein?
S-adenosylmethionine-dependent methyltransferase UmaA, SAM-dependent methyltransferase UmaA.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y740_ENCCU
Sequence: MKFSTLKLATCYLYKVAAEAKVAGKEEFVGDSDSNYQNEYLVTRTTGKDTFTPEMTRKMVLENGLAIVRETTTYVNPYEVKFVPGPVLESLDKVAFASERFGAPNKFIPKPDFSYMEGYNKMAKKTGSSNARTPDEGKKAKNAPEEEKVKTSGSEDAKGEESAVEGKEPEQGENDVEVANPTKSSEKAGFFPNGSFARPSFGKYSSLA
What are the official names of this protein?
Uncharacterized Golgi apparatus protein ECU07_0400.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: RLMN_ECO81
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_BRUMB
Sequence: MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKLSVIGNGVVVDPHHFVAEVEKLRGQGIDVTPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVERLLAHHNSLRRGMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEELIGAPVAMLSTSPEREDTILVTDPFHD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_ALIFM
Sequence: MSRTVFCVRLNKEADGLDFQLYPGELGKRIFDNISKEAWGQWQHKQTMLINEKKLNMMDPEHRKLLETEMEGFLFDGKDVVIDGYTPPSE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: NUOI_RICPU
Sequence: MINYLKSFFLYEIVRGMALTLKYFFKPKVTINYPYEKSPISPRFKGEHALRRYENGEERCIACKLCEAICPAQAIVIEADEREDGSRRTTRYDIDMTKCIYCGLCQEACPVDAIVEGPNFEFASLTHTALIYDKERLLQNGDRWEQALASKLHKDYEYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: E313_ADECU
Sequence: MAMTEESMDQVEVNCLCAQHAQTCTRPRCFAKEGLCANWFYNPALAFEGFDIPDSYQEGHGVDIEVKCSHHSSKLCHNGHDMICSYSRLGSHINIRCICNKPRPHMSLIEAACSMYNLN
What are the official names of this protein?
Early E3 13.3 kDa protein.
Protein: FNRA_STUST
Sequence: MSESIKVRAQRQAHCKDCSLSGLCLPLSLNMQDMDALDDIVKRGRPLKKGETLFRQGDTFSSVFAVRSGALRTFSVTDGGEEQITGFHLPSELVGLSGMDTEMYPVTAQALETTSVCEIPFERLDELSVLLPQLRRQLMRIMSREIRDDQQMMLLLSKKTADERIATFLINLSARFSARGFSANQFRLPMSRNEIGNYLGLAVETVSRVFTRFQQNGLLEAEGKEVRILDSIGLCALAGGAMDA
What is the function of this protein?
Transcriptional regulator of arginine deiminase.
What are the official names of this protein?
Transcriptional activator protein FnrA.
Protein: SYH_CLONN
Sequence: MAIQAPKGTKDLLPMDSYKWHYIEDKLKKLAAEYALKEIRTPAFEHTELFERGVGETTDVVQKEMYTFKDKGDRSITLKPEGTAPAARAFIENGLFNEALPIKMFYFTPVFRYENVQKGRLREHHQFGVEVFGSTEASVDAELIGLAMRAFKEFRIDNLELNINNIGCPECRKKYNDALREYFRESYDELCDTCKTRFERNPMRLLDCKNKKCKEIGKDAPVILDYVCDDCSNHFENLKTYLDSLNIKYKVNPYIVRGLDYYTKTVFEIINNDITVCGGGRYNGLIEQIGGKPTPAVGFGMGIERLILTLMENNIEIPKPKEMDIFIGSMGDNGKIEAFKLVNALRTKGLKAECDHMNKSVKAQMKYANKIDASYSMIIGDTEIEEKKANLKRMEDGQQFEVSLNNLDEIASMILK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRPK1_CAEEL
Sequence: MMIKVGAAINGTDSPKAMKREHDNDDGDRTGRHKRPKTDGFTEAIQQGKFEVRLLVSSKSAGAIIGKGGENIKRLRAEFNAHVQVPDSNTPERVCTVTADEKTVLNILKDVLPRLEDNFSERDPCEVRMLVHQSHAGALIGRNGSKIKELREKCSARLKIFTGCAPGSTDRVLITSGEQKNVLGIIEEVMKELKEIPIKGSATPYLPAFNYDPSNISDYGGFPGNMPAGGPPNNRGPAPQRGGQGPPGGPRSYGGAITQGGGQRSFEAGDFQQFRGGPGPVPGYAMSAPGYPPQQGQFGAPNNAGYGYGPGGGGPVTTAQVTIPSDLGGTIIGRGGERIARIRQESGAQITLEQSNGQPERIITIKGTEQQIHSAQYLLQQCVRNSTQGRERFGGSV
What is the function of this protein?
RNA-binding protein which functions together with alg-1, a component of the miRNA loading complex, to modulate the processing and activity of specific miRNAs such as miR-58 and let-7 to regulate gene expression at the post-transcriptional level during embryonic, hypodermal and neuronal development (PubMed:31584932).  Promotes the lsy-6-mediated repression of cog-1 in uterine cells (PubMed:31584932).  In embryos, may play a role in the DNA damage response (PubMed:15654100).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein K homolog, hnRNP K.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to the cytoplasm and nucleus in the germline, oocytes and early embryos (PubMed:31584932). Does not localize to the cytoplasm of somatic cells (PubMed:31584932).
Protein: TRPB_KLEP7
Sequence: MSTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPAFQAEFTDLLKNYAGRPTALTKCRNLTEGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYEKAHYMLGTAAGPHPFPTIVREFQRMIGEETKAQILEKEGRLPDAVIACVGGGSNAIGMFADFIEETNVGLIGVEPAGHGIESGEHGAPLKHGRVGIYFGMKSPMMQTADGQIEESYSISAGLDFPSVGPQHAFLNSTGRADYVSITDDEALDAFKALSRHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: CYSD_PSYIN
Sequence: MKKNRLTHLKALEAESIQIMREVAAEFDNPVMLYSVGKDSSVLLHLARKAFYPGKIPFPLLHVDTNWKFKEMIAFRDNIAKKYDFDLLVHKNPRGMEMGISPFEHGSAKHTDIMKTEGLKQALDKYGFDAAFGGARRDEEKSRAKERVYSFRDKKHRWDPKNQRPELWNIYNAKVDRGESIRVFPLSNWTELDIWQYIYQEDIEMVPLYFAKKRPVVERDGALIMVDDERMPLKEGEVPEMKMVRFRTLGCYPLTGAIESQATTLPEIIQEMLLTTTSERQGRVIDNDSAGSMEKKKMEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: DUT_CLONN
Sequence: MKLLVEKTNEKAIIPFQAHEGDAGMDLFSVEEITLKPMERKLIHTGIKIQLPKDTEAQIRPRSGLALKHGITVLNTPGTIDEGYRGEIGIILINLGSEEFKVEEGMKIAQMVIKPTLTLKVEEVVELTETTRGENGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ATPG_ACIF2
Sequence: MANAKEIRGQIKSVKNTRKITRAMEMVAASKMRRAQERMRAARPYAEKIREVLGHLAQAHPEYEHPLMQVRPVKKAGFLVVTTDRGLCGGLNVNVLRNVVQKMRELHEEGVESNLAVVGNKGLGFLRRHGAHLVAELNGLGDSPHLGDMIGPIRAMADAYAKGEVDVVYLVSSRFVNTMLQRATVEQLLPVEKPTASAEQRAELWDYIYEPEARPVLDRLMQRYVESVVYQAVIEHLACEQSARMVAMKSASDNAKRMVDDLQLAYNKARQAAITQEIAEISAGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL2_MYCGA
Sequence: MPVKKIVNRSNSGIHHKISIDYSKVLTTNTPQKSLLAKKKKNSGRNNQGKITVRHRGGGSKRKYRIIDFKRNLHDDKIALVKSIEYDPNRSAFISLIAYENGYRSYILTPQGIKVGDKVVSSSQAIDIKVGNCMPLEFIPEGTMVHNIEMTPGKGAQIARSAGAYAQILGKDDTGKYINLKLGSKEVRKFLKNCRAVVGIASNVDHNLVLLGKAGTTRHKGIRPTVRGSAMNPNDHPHGGGEGRSPVGRDAPRTPWGKRHMGVKTRNNKKSSTQLIIRRRNSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TRI56_MOUSE
Sequence: MNSKVSSPTLLEALSSDFLACKICLEQLHTPKTLPCLHTYCQDCLAQLDIGGQVRCPECREIVPVPAEGVAAFKTNFFVNGLLDLVKARAPGDVHSGKPTCALCPLVGGKSSGGPATARCLDCADDLCQACADGHRCSRQTHKHRVVDLVGYRAGWYDEEARERQASQCPQHPGEALCFLCQPCSQLLCKDCRLGPHIDHPCLPLAEAVRSRKPGLEELLAGVDSNLVELEATRVAEKEALALLREQAASVGTQVEEAAERILKSLLAQKQEVLGQLRALVEAAEEATRERLTKIERQEQVAKAAAAFARRVLSLGLEAEILSLEGAITQRLRQLQDAPWTSGPTRCVLPQLELHPGLEDKNCHLLRLIFEEPKQSPKDSGKGGAGTQGGDEAQGQGDDRTKIGKQGGAQPLTPKEGKDQNPQEDDGVFIERGNRPNKKKKCKGRGKSVSREPSPILRPNLEGSGLLPRPVFSWSFPTRMPGDKRSPRITGLCPYGPQEILVADEQNRVLKRFSLNGDYKGTVQVPEGCSPCSVAALQNAVAFSANAKLYLVSPDGEIQWRRSLSLTQSSHAVAAMPCGDRVAVSVAGHVEVYKKDGSLATRFIPGGKASRGQRALVFLTTSPQGNFVGSDWQQNSVVFCDGLGQVIWEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGKYLVVSLSNGTIHVFRVRFPDS
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity by mediating ubiquitination of CGAS and STING1 (PubMed:21074459, PubMed:29426904).  In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets STING1 to 'Lys-63'-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta (PubMed:21074459).  Also mediates monoubiquitination of CGAS, thereby promoting CGAS oligomerization and subsequent activation (PubMed:29426904).  Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling (By similarity).  Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXCL10, OASL and CCL5/RANTES (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM56, Tripartite motif-containing protein 56.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.