PharMolix/UniProtQA huggingface dataset:
Protein: NGP_MOUSE
Sequence: MAGLWKTFVLVVALAVVSCEALRQLRYEEIVDRAIEAYNQGRQGRPLFRLLSATPPSSQNPATNIPLQFRIKETECTSTQERQPKDCDFLEDGEERNCTGKFFRRRQSTSLTLTCDRDCSREDTQETSFNDKQDVSEKEKFEDVPPHIRNIYEDAKYDIIGNILKNF
What is the function of this protein?
Acts as an inhibitor of cathepsin B (CTSB) activity.  Plays a role as a negative regulator of tumor vascular development, cell invasion and metastasis.
What are the official names of this protein?
Neutrophilic granule protein, NGP, Cystatin-like protein, Myeloid bactenecin protein, Myeloid secondary granule protein.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Localizes in cytoplasmic granules of neutrophilic precursors (PubMed:8749713).
Protein: MINE_XANOM
Sequence: MGLLDFLKSKKNTAETAKNRLQIIIAQERNHRGGPDYLPLMQRELLEVIKKYVNIDADAVRVDLVKDGEHDVLDISVALPEDGDK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: PVG1_SCHPO
Sequence: MFANINIRKSVWLFLLAAVSCTLFIYGVTRTDLQTLKNPSSLTSPSSSTSVDKKKPLFTKSPRNSASCESTITLQSNLLFTYYKHYFAGIKKVALIGFPDHPNKGDSAIYVAEKKLLDALNIEVVYITAQEADYSASELKSIISDIPRDEFALAFHGGGNFGDLYPDHQHLRELVVRDFPSFTTISFPQSVWYNEQQLLEQASILYAENPNITLVTRDRQSYGFAVDAFGKHNEVLLTPDIVFFMGPIPEIREATPITHDVLILARLDHEGGQQHGAEDYYRDTLNAANLTYSVEDWLLWDPPVAQNPDSSFDDRGQARYEAGAEFLASARVVITDRLHAHILSTLMGIPHIVVENSQMGKITNYHNTWLHGCTLDGVSVVVDSVDKALSLLLEWNEAGYF
What is the function of this protein?
Involved in cell wall biogenesis.  Has a role in the addition of Gal-beta1,3 moieties to galactomannans and their subsequent pyruvylation.
What are the official names of this protein?
Pyruvyl transferase 1, Pyruvylated Gal-beta-1,3-epitope synthesis protein 1, PvGal synthesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide pyruvyl transferase family.
Protein: RL18_METM5
Sequence: MAKNAKFRVPFRRRREGKTDFRQRLGLLLSGKPRLVARKSLNNVTAQLMSYDEKGDVVLVSAHTKELVKMGYKGHCGNLPAAYLTGLLLGKKAVKEGAEEAILDKGLHRATKGAAIFAVLKGALDAGMDIPHGDEIIAEEERLNGTHVKNYAESLKEDADAYKKQFSKYLEKGLNPEDLPEHVAELKEKILNL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SYK_MESM1
Sequence: MNQKLSEQELIRRQKIEKLQKLGVEVFHETVKFDLNINKIIQKYNSFSKDELAKDEFSLSTTGRIITIRSSFLVLKSQGSKFQIYLPIKELDKKYLELIDLLDIGDIIFVNGKLMKTQTGELTLRANELKLLSKSLKVLPDKFHGLNDIEERYRHRYVDLIVNDDVRKTFLLRSRIISLIRKYFDNLEYLEVDTPVLQPILGGASAKPFITKFNALNSNFYLRIATELPLKKLVVGGFDRVYEIGRIFRNEGVDTTHNPEFTSIEYYEAYSNNEGMMNRTEDLFKFIAKELNLKTIFFNGYEIDLNKPFRRLNMVEALNEKLGIDLYKISFEDAKVLAKKHHIKVESYFKIGHIINELFELFIEKDLIQPTFVYGHPIEISPLANKNKKNPNFTDRAELFIGTKEYANMFTELTDPIDQLERFKDQQNEKDNGNEEANEIDYDFVEALEYGLPPTGGCGIGIDRLVMLFTNNESIREVLLFPHLKNK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: TBA1C_BOVIN
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNYARGHYTIGKEIIDLVLDRVRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLMSQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGDDEGDEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569).  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
What are the official names of this protein?
Tubulin alpha-1C chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ATC7_YEAST
Sequence: MPNPPSFKSHKQNLFNSNNNQHANSVDSFDLHLDDSFDAALDSLQINNNPEPLSKHNTVGDRESFEMRTVDDLDNFSNHSSDSHRKSSNTDTHPLMYDNRLSQDDNFKFTNIASSPPSSSNNIFSKALSYLKVSNTKNWSKFGSPIELSDQHIEREIHPDTTPVYDRNRYVSNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNELYHVITRNRSIPSKDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLSENDLINRISITASAPEKSIHKFLGKVTYKDSTSNPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEINSISKILCACVFALSILLVAFAGFHNDDWYIDILRYLILFSTIIPVSLRVNLDLAKSVYAHQIEHDKTIPETIVRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSYTSETLDIVSDYVQSLVSSKNDSLNNSKVALSTTRKDMSFRVRDMILTLAICHNVTPTFEDDELTYQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKTLNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVMSKIVESNDWLEEETGNMAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITKVTRPEGAFNQLEYLKINRNACLLIDGESLGMFLKHYEQEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTELLLWHGRNSYKRSAKLAQFVMHRGLIIAICQAVYSICSLFEPIALYQGWLMVGYATCYTMAPVFSLTLDHDIEESLTKIYPELYKELTEGKSLSYKTFFVWVLLSLFQGSVIQLFSQAFTSLLDTDFTRMVAISFTALVVNELIMVALEIYTWNKTMLVTEIATLLFYIVSVPFLGDYFDLGYMTTVNYYAGLLVILLISIFPVWTAKAIYRRLHPPSYAKVQEFATP
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids (Potential).  Leads to neomycin-resistance when overexpressed.  Required for traffic between late Golgi and early endosomes.
What are the official names of this protein?
Probable phospholipid-transporting ATPase NEO1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: MAMU_MAGSA
Sequence: MRIAAIINERAGTVACLSPPVVAARLSAIWTSLGHQAHVTLAEGKDMGRAIRKACRDPAVHAVIIGGGDGSLSRSLKHVVGSGKSLGVLPLGTMNYVARQFGVPFDLDRAAVALADAVPTPTDLGRVNDRFFLIRACLGAFPEFIRSRDEARRKGGSFLDGALAGLTGLARGHRLIEAELIGPDVQARIATSFFMVSNNMCRDSDPFQLERERMDGATLGVYIGQGAGPFSLMDLGLQVAMGRWASNEALIRGSLPWLEIRTRQRKPLVSIDGEVEKMEAPFRFDILPGVLPMLVPK
What is the function of this protein?
Might phosphorylate lipids.
What are the official names of this protein?
Putative lipid kinase MamU.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Tagged protein forms a diffuse intracellular stain.
Protein: STHA_YERPE
Sequence: MQQHFHFDAIVIGSGPGGEGAAMGLVKQGARVAVIERYNNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDNARTIKSSFADILNHADRVINQQTRMRQGFYDRNHCHMFSGDASFIDANTVNVRYADGTSDTLQADNIVIATGSRPYRPVNVDFNHERIYDSDTILQLSHEPQHVIIYGAGVIGCEYASIFRGLSVKVDLINTRDRLLAFLDQEMSDALSYHFWNNGVVIRHNEEFEQIEGTTDGVIVHLKSGKKVKADCLLYANGRTGNTSGLGLENIGLEADSRGLLKVNSMYQTALSHVYAVGDVIGYPSLASAAYDQGRIAAQAMIKGEANVHLIEDIPTGIYTIPEISSVGKTEQELTAMKVPYEVGRAQFKHLARAQIVGMDTGSLKILFHRETKQILGIHCFGERAAEIIHIGQAIMEQKGEGNTLEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFS_SERP5
Sequence: MSFPIERVRSEFPLLAREVNGQPLAYLDSAASAQKPQAVIDRELDFYRHGYAAVHRGIHTLSAEATQEMEAVREKVAAFINAGSAEEIIFVKGTTEGINLVANSFGRHFLQPGDSIIITEMEHHANIVPWQMLAQERGLNLRVWPLQPDGTLDLARLPGLIDASTKLLALTQVSNVLGTVNPVQEITAQAKAAGLKVLIDGAQAVMHQRVDVQALDCDFYVFSGHKLYGPSGIGILYGRQALLQQMPPWEGGGSMIQQVSLTAGTTYAEPPWRFEAGSPNTAGMMGLGAAIDYVNTLGLEAIGDYEQSLMHYALEALQQVPRLKIYGPAERAGVIAFNLGEHHAYDVGSFLDQYGIAIRTGHHCAMPLMAFYNVPSMCRASLALYNTRDEVDRLVAGLQRIQKLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_CHLL3
Sequence: MRIILLGAPGAGKGTQSNYISKSLAIPQISTGDMLRAAVKAGTPLGLKAKEVMDGGNLVSDDIIMDIIKERLLEHDCKEGCLFDGFPRTIAQAESLDRQGIDIDHVIEIHVDDREIIDRMSGRRVHPASGRTYHIRFNPPQTAGMDDETGEPLVQRADDTEETVKKRLEIYHDQTAPLIEYYSRRAAGAGTGAFAPRYTRIEGTGSVEEIRDRILEALRG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y234_HALH5
Sequence: MMERIQELLEQIVKWLIFTILLVASISLIVVYQQGYIAEALVARATPLAIVVGLSAIAAAIIVKK
What are the official names of this protein?
Uncharacterized protein BH0234.
Protein: MPRF_BACSU
Sequence: MLIKKNALSILKIVFPIAVLLFVIYQSKKELTNLSFKRTLMVINGLERTDLFMLVLIGLLAVAAMSLYDYVLKYSLRLSITNGKVFRVSWIANSFNNVLGFGGLAGVGLRMMFYKEHTKDHKALVKGIAWLTSSMLLGLSVFSIFVAARVLPVDEVIHEKPWLWAVVIGFALILPLSLAVSKIKDRKAGDEENADKVKNPIFAYIGASVVEWLMAGTVIYFALFAMGIHADIRYVFGVFVIAAIGGMISLVPGGFGSFDLLFLLGMEQLGYHQEAIVTSIVLYRLAYSFIPFILGLFFAAGDLTENTMKRLETNPRIAPAIETTNVLLVVQRAVLVRILQGSLSLIVFVAGLIVLASVSLPIDRLTVIPHIPRPALLLFNGLSLSSALILLILPIELYKRTKRSYTMAITALVGGFVFSFLKGLNISAIFVLPMIIVLLVLLKKQFVREQASYTLGQLIFAVALFTVALFNYNLIAGFIWDRMKKVLRHEYFVHSTSHITHATIMAIIIVPLFFLIFTVVYHKRTKPIGEKADPERLAAFLNEKGGNALSHLGFLGDKRFYFSSDGNALLLFGKIARRLVVLGDPSGQRESFPLVLEEFLNEAHQKGFSVLFYQIEREDMALYHDFGYNFFKLGEEAYVDLNTFTLTGKKKAGLRAINNRFEREEYTFHVDHPPFSDAFLEELKQISDEWLGSKKEKGFSLGFFDPSYLQKAPIAYMKNAEGEIVAFANVMPMYQEGEISVDLMRYRGDAPNGIMDALFIRMFLWAKEEGCTSFNMGMAPLANVGTAFTSFWSERFAAVIFNNVRYMYSFSGLRAFKEKYKPEWRGKYLAYRKNRSLSVTMFLVTRLIGKSKKDSV
What is the function of this protein?
Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge.  LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects B. subtilis against its own CAMPs and against those produced by competiting microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
What are the official names of this protein?
Phosphatidylglycerol lysyltransferase, Lysylphosphatidylglycerol synthase, LPG synthase.
What is the protein family that this protein belongs to?
Belongs to the LPG synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localized in the septal membrane.
Protein: RSMA_STRA1
Sequence: MRIADKTVTRAILERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDKGVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLIPILADTLARFDNVQVVNQDILKADLQTQIQAFKNPDLPIKVVANLPYYITTPILMHLIESKIPFAEFVVMMQKEVADRISAMPNTKAYGSLSIAVQYYMTAKVSFIVPRTVFVPAPNVDSVILKMVRRDQPVVSVQDEDFFFRVSKVAFVHRRKTLWNNLTSHFGKSEDTKAKLEKALEIAKIKPSIRGEALSIPDFASLADALKEVEI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSCB_ARTGP
Sequence: MGGRLPFNQSFWEEFLMGREGSLPNLPEISHVSKRVVRILGGNPGSMHLQGTNTYLVGTGRSRILIDTAQGLPAWIHRISSFLFTHNIELSYVLLTHWHGDHTGGVPDLIAHNPLLTNKIYKNNPDAGQNTITDGQIFSVNGATVRAVFTPGHSVDHMCFVLEEENALFTGDNVLGHGFSVAQDLGCYMDSLRNMSALACGLGYPAHGAIIENLPGKLDEYIQHREGRERMMLSTLTKELVQGQERRGEGTKGGLTLNEIVISIYGRLPQEVIEKALAPSLLQVLWKLTEDRRVGFKPGDPLKRQWFALISVE
What is the function of this protein?
Lactamase-like protein; part of the gene cluster that mediates the biosynthesis of neosartoricin B, a prenylated anthracenone that probably exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (By similarity).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (By similarity).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (By similarity).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (By similarity).  Neosartoricin B can be converted into two additional compounds neosartoricins C and D (By similarity).  Neosartoricin C is a spirocyclic compound that is cyclized through the attack of C3 hydroxyl on C14, followed by dehydration (By similarity).  On the other hand, neosartoricin D is a further cyclized compound in which attack of C2 on C14 in neosartoricin C results in the formation of the acetal-containing dioxabicyclo-octanone ring (By similarity).  Both of these compounds are novel and possibly represent related metabolites of the gene cluster (By similarity).
What are the official names of this protein?
Lactamase-like protein nscB, Neosartoricin B biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: MINE_VIBVY
Sequence: MSLLEFFRPQKKTSASLAKERLQIIVAERRSQNDPAPSYLPQLKEDILKVISKYVAIDPAMVDLTFEHKDDDISVLELNVKLPDEEK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SSB_AQUAE
Sequence: MLNKVFIIGRLTGDPVITYLPSGTPVVEFTLAYNRRYKNQNGEFQEESHFFDVKAYGKMAEDWATRFSKGYLVLVEGRLSQEKWEKEGKKFSKVRIIAENVRLINRPKGAELQAEEEEEVPPIEEEIEKLGKEEEKPFTDEEDEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: MIAB_BRASB
Sequence: MTPPRKLHIKSYGCQMNVYDAQRMVDTLGAEGFVETAEAGDADLVILNTCHIREKASEKVYSELGRLRVAKEEAARQGRAMQIAVAGCVAQAEGAEIVTRAPTVDVVVGPQSYHHLPELLARAGRGEPAIETEFPAEDKFGFLARPSREAIRARGVSAFVTVQEGCDKFCTFCVVPYTRGSEMSRPVARILDEVTRLTENGVREITLIGQNVNAYHGEAPDGSTWTLGRLLYGIAEIPGVARIRYSTSHPNDVDDSLIAAHRDLASVMPFVHLPVQSGSDRILGLMNRKHGASDYRKVVDRFRAARPDIAFSSDFIVGFPGETEEDFRATLALIAQIGYAAAYSFKYSPRPGTPAADMQEMVSATEMDERLERLQSLIDSQQAAFNKAAIGTVVDVLFERAARKPGQLVGRTAYLQPAHVMAPDNIIGQVLPVRIDSLERYSLLGELVATAAPVAGAATPLVSIGG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCN5_DEBHA
Sequence: MVDRKRNSSVISDNEENGRVDKKTKIKDEIEGDEVERDVKNEEANGADTDDKEEVRKDNEEENAENGGGEGDDDDDDDDEAEEEKKRTTTFNFDGVTYSFKERPSVLEEKEGKIEFRVVNNDNTKESLMVLTGLKNIFQKQLPKMPREYISRLVYDRSHLSMAVVRKPLTVVGGITYRPFDNREFAEIVFCAISSTEQVRGYGAHLMNHLKDYCRATSNVKYFLTYADNYAIGYFKKQGFNKEITLDKSVWMGYIKDYEGGTLMQCSMLPPILRYLDSAKILLLQKAAIEKKIKLRSKAHVVRPGLQVFKTNKDAKLNPAKDIPGLAESGWSEEMDKLAQKPKRGPHYNFMVTLLSELTNHPSAWPFSTPVNKEEVGDYYDVIKEPMDLSTMESKLENDKYDSFDQFLYDARLIFNNCRSYNADSTTYFKNATKLEKFMNNKIKDSAEYSHFLDQ
What is the function of this protein?
Histone acetyltransferase that acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, with a lower preference histone H4 to form H4K8ac and H4K16ac, and contributes to H2A. Z acetylation.  Acetylation of histones gives a specific tag for epigenetic transcription activation.  In addition to histone acetyltransferase, can use different acyl-CoA substrates, such as (2E)-butenoyl-CoA (crotonyl-CoA) and is able to mediate histone crotonylation.
What are the official names of this protein?
Histone acetyltransferase GCN5, Histone crotonyltransferase GCN5.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GCN5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CD15L_HUMAN
Sequence: MFSCCFPTSRGCCFRNGGSESLFRQCRRRLIPHPRRLWPFVRRRTQVPQDSPGQALAGQATPEIPSGLPLHIVLVQEEIREPMEAQTHAPGPYADIAALAAPAVEPKPAWEEPPPERALEVEGAPAKDQPSQELPEIMAPTVATGLNAGAENVAGERSGREGVTSTAPASRSHAAPSPGHGGKHGGGDQGIQTGLLYLAGERLLSFAGTTALLLQGLFIVLILVGYISVKVMLKSIKTRLGRRVPAAPPALRRNLLLQAWKCVCNWASRLFAPNVLPRTGS
What are the official names of this protein?
CMT1A duplicated region transcript 15 protein-like protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYE_FRASN
Sequence: MSTGRVRVRFAPSPTGIFHVGGARSALFNWLVAKGAGGDFVLRVEDTDASRNRPEWTEGIISALDWLGISPGGYEGPVFQSERAGRHAEAAAGLFAAGRAYYCGCTRDELAARTGNAQHGYDGFCRERGLGPGPGRALRFRTPDEGTTVVLDVIRGTPEFPNDTIEDFVIARADGSAVFLLANVVDDLDMGITHVVRGEEHLSNTPKQQLLWAALGTPPPVWAHVPVIVNEKRQKLSKRRDKVALESYRAEGYLAAAMCNYLMLLGWAPPGDEEIVPFETIEASFRLEDVKPSPAFFDEKKLRAFNGEYIRALSVDEFVAACEPWLVPAADVPAAVDAPAAAGTGDGAAGVTTAVPAPPWSPERFSAEVFAAVAPLAQSRVAVLSEIVPMVDFLFLPEAPTDEAAWAKTMKGPALDLLTEAAEAYEKVAWDHDVLRETLIEVGERHGLKLGKAQAPVRVAVTGRTVGLPLFESLEILGREETLRRLRAAVERLDTAANPA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_ACTPJ
Sequence: MFKMVSSPHTHSSNLTAKFMLWVMVAMLPALGMQAYFFGYGVFIQVFIALLLAVAIEIAIAKLRRKLTAFYVADLSGVLTALILAISIPPYAPYWIIVIGIIVALLLAKHSYGGLGQNLFNPAMVAYALLLVSFPVQMTGWLVPIDLLNEPPTFGDAISLVFSGVTSDGFSVHQLLGSVDGIAQATPLDSAKTSMQKLGVEGVLQSPIFSGLFANGWWQINLAFLAGGLLLIYKRIIHWQIPAAMLGMFALLSGLTDLLLPHTHLNVVSQLFSGAMMFGAFFIATDPVTASITPRGKLIFGGLIGLFVYLIRYYGNYPDAVAFSVLLANICVPLIDHYTQPRLYGTGR
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_ACET2
Sequence: MARYTGASCRLCRREGEKLYLKGERCTTNKCAIARRGYAPGQHGQNKKKLSEYGLQLREKQKARRYYGILEGQFRRYFEMAVKKKGITGENLLQILESRLDNVVYRMGLAVSRREARQLVRHGHFTVNGKRVDIPSYLVKVGDVIAVKEKSKSSPKMQSNKEYAAGRPRPKWLEYDAEEMSGKVVALPAREDIDLPIRENLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GOME_ACAGO
Sequence: MNRTRLFACLLLAVLILVHESNAQCRRLCYKQRCVTYCRGRGKRSLDETNVGTSDVEKRAFDDSNVPSLVEERELEDEGSFIFD
What is the function of this protein?
Active against several Gram-positive bacteria such as Bacillus spp, Staphylococcus spp and E. faecalis, several Gram-negative bacteria such as E. coli, K. pneumoniae, P. aeruginosa and Salmonella spp, filamentous fungi such as N. crassa, T. viridae and yeasts such as C. albicans.  It is active against the parasite L. amazonensis as well.  It shows hemolytic activity.
What are the official names of this protein?
Gomesin.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAJ_NITEU
Sequence: MSQSDYYEVLGVGRDADENELKKAYRKLAMKYHPDRNAGDTKAEERFKNIKEAYEILSDPNKRAAYDQFGHAGLNGGMGGAGAQGFSDAFSDIFSDLFGMRGGGRSSVHRGADLRYNLEITLEQAARGAETQIRIPRQEVCDTCHGSGAKPGTSPKTCPTCNGHGQIRMQQGFFSIQQTCSHCQGSGKVVSDPCGDCHGAGWVKRQKTLSVRIPAGVDEGDSIRLTGEGEAGANGGQAGDLYIVIHLASHPVFQREGNHLHCEIPISFTVAALGGEIEVPTLDGHARIKVPAGTQTGKIFRLRSKGITGVRNQSTGDLLCHVAVETPVDLTARQKELLEEFESISQKDGSRHHPRAKSWMEKAREFFAE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.