PharMolix/UniProtQA huggingface dataset:
Protein: ITA8_MOUSE
Sequence: MSAGTHCGPPGNRAPPFARLCCVSAALGMLWSPACLAFNLDVDKLTVYSGPEGSYFGYSLDFYIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPSERSAQCKQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVRAHKGKVVACAPLYHWRTLKPNPAKDPVGTCYVAIQNFSAYAEHSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITVSIADIIANYSFKDILRKLAAEKQTDVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNNDGMDDILVGAPLFMEREFESNPREVGQVYLYLQASALLFQDPQVLTGTETFGRFGSSVAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNPRGLHSKPSQVLQGIWGSQTIPSGFGFSLRGDADIDKNDYPDLLVGAFGKGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQIPEFPTPVACFSVRVCASIAGQSISNTIALLAEVQLDFLKQKGAIKRTLFLHNHQSHFTFPFVMKQQKSLHCQDFMVYLRDETEFRDKLSPINISLNYSLDDSTFKDSLEVKPILNHYRDNVVTEQAHILVDCGEDNLCVPDLKLSARPDKHQIIIGDENHLMLIINARNEGEGAYEAELFVIIPEEADYVGIERNNKGLRPLSCEYKMENVTRMVVCDLGNPMVTGTNFSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFERVQINITAIAQVEIRGVSHPPQIVLPIHNWEPEKKPHKEEEVGPLVEHIYELHNIGPSTISDSILDVGWPFSARDEFLLYIFHLQTLGPLQCQTNPEINPQDIKPAASPEDTPELSAFLRNATIPHLVRKRDVPVVQLHRQSPARILNCTNIDCLQISCAVGRLGGGESAVLKVRSRLWAHTFLKRKNDHYALASLVSFEVKKMPYKEQPAKLPAGSTAVKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQDEMTDREQLTSDKTPEA
What is the function of this protein?
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures.  It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN.  NPNT is probably its functional ligand in kidney genesis.  Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
What are the official names of this protein?
Integrin alpha-8.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cell membrane.
Protein: NANM_SALPB
Sequence: MGMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDELYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNEHIFDKYFIDIAAAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPDAGTAGSSSVMENNFLMLINGELKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGINKKWRDEVYGLVNGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VM25A_MACLO
Sequence: NSGNPCCDPVTCQPRRGEHCVSGKCCRNCKFLRAGTVCKRAVGDDMDDYCTGISSDCPRNPYKD
What is the function of this protein?
Poor inhibitor of platelet aggregation.  The disintegrin inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) integrin to VCAM-1.  Inhibition on alpha-IIb/beta-3 (ITGA2B/ITGB3) is low.
What are the official names of this protein?
Disintegrin VLO5A.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIe sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIG_HELHP
Sequence: MNHIKDTLKIGSHTFASRLIVGSGKYKDFATTKEATLASGAEIITVAVRRVNIMDNKSENLLETFKDTNIQFLPNSAGCVNAKEAITLFRLVREATGIDFIKLEIIGDIDKTLYPDVIESLQATEILANEGFCVLAYTNDDPIMAKRLENAGASAIMPLAAPIGSGLGIQNRYNIGFIKEAVKVPVIVDAGVGCASDASIAMELGADAVLTNTAIAQAQNPVTMAEAMKYAVKAGRLSYLAGRIPRKAYASASSPLEGMMQFG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_STRGC
Sequence: MKQIQIAIDGPASSGKSTVAKIIAKDLGYTYLDTGAMYRAATYLALQHQLTAADTEDIIRLLDDYSVSFGRSESGQQLVFVGDVDVTNPIRENDVTNNVSWVSAIPEVREKLVSLQQQIASQGGIVMDGRDIGTVVLPDAELKIFLVASVDERAERRYKENLERGISADLEVLKKEIADRDYKDSHRSVSPLRPADDSITFDTTGVSISDVVAFIEEKAKKILDK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRFC_ORYSJ
Sequence: MPPLHAVSPAAAAAPPRALSSAARVPQRPGCVPERPNILSSSTNFMSLRAGPMRFYSRPLILQNSDKRAVLRHATIEEIEAEKSVIEDQARERMEKAIETVQNNFNTVRTGRANPAMLDRIEVEYYGTPVNLKSIAQINTPDATSLLIQPYDKSSLKLIEKTIVAANLGVTPSNDGEVIRVTVPPLTSDRRKELAKTVAKLAEEGKVAIRNIRRDAIKAYDKLEKEKKLSEDNVKDLSADLQKVTDEYMKKIEAIQKQKEQELMKI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis.
What are the official names of this protein?
Ribosome-recycling factor, chloroplastic, RRF, Protein OsL8, Ribosome-releasing factor, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2239_PHOPR
Sequence: MNLSAKTVVLIAIGAALYGIGGLPMFGIPVFANTTLKPAMAVLALFSVLFGPLVGFLVGFIGHWVTDMFAGWGVWLTWVLGSGLVGLIIGFYPKITRGRLEMGKFTKCDFALFVFLAFLGNVIGYGCSAYLDSVLYAEPFTKVVAQLIIIAAGNTLLIAIVGHYILTAVAKRKQQSYNLKEAD
What are the official names of this protein?
UPF0397 protein PBPRA2239.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPD_STRR6
Sequence: MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ATPL_ACTP7
Sequence: MESVITATIIGASILLAFAALGTAIGFAILGGKFLESSARQPELASSLQTKMFIVAGLLDAIAMIAVGISLLFIFANPFIDLLK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLD_BORPE
Sequence: MTEPNDTGPALQAEHLGKVYDEGPARIEVLSDVSLSVARGEMVAIVGASGSGKSTLLHILGLLDVPSSGTVSVDGVPAAGLSEKRKSALRNRSLGFVYQFHHLLPEFSALDNVAMPLIVRRENRDRARAQAREVLELVGLAAREEHFPGQLSGGERQRVALARALVTRPACVLADEPTGNLDRHTAHNMFELLTRVNRESGTAFVIVTHDPELAARADRQLHMENGRLQPD
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MSHR_MAMPR
Sequence: MPMQGAQGRLRGSLNATPPTTPHSGLAGNQTGPWCLEVSIPDELFLSLGLVSLVENMLVVAAIAKNRNLHSPMYYFICCLAVSDLLVSVSNVLETAVMLLLEAGVLAAWAGVVQQLDNAIDVFICGSMVSSLCFLGAIAVDRYITIFYALRYHSIVTLPRARWAIATIWAASVVCSTLFIAYYDCTAVLLCLVSFFLALVVLMAVLYMHMLARACLHARSIARLHKRWRPVHQGLGLKGAATLSILLGSFFLCWGPFFLHLTLIVLCPQHPTCSCVFKNFKLFLTLIICNSIVDPLIYAFRSQELRKTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTS_SHEPW
Sequence: MTAIEPQNLEKHTPMMRQYLTLKAQHPDMLLFYRMGDFYELFYEDAKLASELLGISLTARGKSGGDPIPMAGLPYHAVEGYLAKLVQLRVSVAICEQIGDPATSKGPVERKVVRIVTPGTLTDEALLQERQDNLLAALYQGKSGYGYATLDIASGRFVITELANTEALEAELQRTNPAELLYSEDFSQMSLIAGMNGTRRRPEWEFDFDTCQRLLLNQFGTKDLNGFGIEGARLSLQAAGCLMQYVKDTQRTALPHINSIVRFNQTDSIVLDAATRRNLELTVNLQGGHTNTLASVLDSTVTAMGSRMLQRWLHQPLRDHQVIKARQSSIAELIATENYQLLAEDLKALGDVERITARIALRNARPRDFARLRQALGLLPQLQQTLKASSEPHLQYLSQVIGEFPEELALLSRAVVDNPPMLIRDGGVIRDGYDAELDEWRVLSAGATDYLTQLEAREKEQTGISTLKVGYNRVHGYYIEVSRRESDLVPLSYQRRQTLKNTERYIIAELKEHEEKVLSSQGKALALEKQLWEELFDLILPKLHELQEFATAAAELDVLCNFAECAETLNYACPELSDASGIHVEAGRHPVVEQVSQSPFIANPVTLNSQRKMLIVTGPNMGGKSTYMRQIALITLMAHIGCYVPAEHAVIGPVDRIFTRIGASDDLASGRSTFMVEMTETANILHNATPNSLVLMDEIGRGTSTYDGLSLAWSAAEYLANNLNAMTLFATHYFELTQLPEQIKNVENVHLDAVEHGDSIVFMHAVQEGPASRSYGLQVAALAGVPNSVICAAKQKLHHLESRDHALEQSKNGEMAVQQTISFPTQPTSPVIEALEKLNPDELTPRQALDYLYNLKKMAR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: VAPB4_MYCTO
Sequence: MSATIPARDLRNHTAEVLRRVAAGEEIEVLKDNRPVARIVPLKRRRQWLPAAEVIGELVRLGPDTTNLGEELRETLTQTTDDVRW
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Antitoxin that counteracts the effect of the VapC4 toxin (By similarity).
What are the official names of this protein?
Antitoxin VapB4, VapB-mt4.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: YBEY_STRAW
Sequence: MSIDVNNESGTEVDEQAILDIARYALARMRIHPLSELSVIVVDADAMEQLHIQWMDLPGPTDVMSFPMDELRPPMKDDDEPPQGLLGDIVLCPEVAERQGKEAPTQHSMDEELQLLAVHGVLHLLGYDHEEPDEKAEMFGLQAAIVDGWRAEKGLTGPSPAPTVS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_PINCE
Sequence: MDEFHRYGKEDNSRQQCFLYPLFFQEDLYAISHDHYLDGSSSSEPMEHLSSNDQFSFLTVKRLIGQIRQQNHSIVLFVNCAPNPLADCKKSSYSESVLEGLTLVLEVPFSIRSKYSVEGMNEWKSFRSIHSIFPFLEDKFPHSNYISDARIPYSIHPEILVRTFRRLIRDAPSLHPLRSVLYEYRNSPENLQRSIIVVPRVNTRFFLFLWNYYVYECESILFSLLKRSSHSRSLAHRPFPHGTHFHRKIKHIIIFSRRNSLKSIWLLKDPKINYVRYGERSIIAIKGTHLLVKKCRYYLLLFRQCYFHLWSEPYRVCSHQLSKNCSSSLGYFLRVRMNPLFVRTKMLDELFIADLITNEFDPIVPIVPILGLLAREKFCDVSGRPISKLSWTNLTDDDILNRFDQIWRNLFHYYSGSFGRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELLSKIVFKRTRFDSLPFSSKAAARSQRERIWHSDIPQINPLVNSWQKIQDLKIENLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GATB_RICCN
Sequence: MAYIEGNTGKWEYVIGLEIHAQISSKSKLFSGSSTIFAANPNSQVSYVDAAMPGMLPVLNKHCVHQAIKTGLGLKAKINKYSVFDRKNYFYADLPQGYQISQFYYPIVQNGTMEIPTSTGDLKTIRINRLHLEQDAGKSMHDQSPHYSFIDLNRAGIGLMEIVTEPDISSPEEAAEFVKKLRNLLRYIGSCDGDMEKGSMRCDANISVRRSGEPLGTRCEIKNINSIRNIIKAIEFEAKRQVDLLESGEKIIQETRLFNADSGETRTMRLKEEALDYRYFPDPDLLPLVISDELINELKANLPELPDQKIEKYTKEFSLSKYDAEVIVADESVAEYFEKAANECNPKMLTNWLTSELFGQLNKASIGINECKITPSNFAKLVKLIENDTISGKIAKTVFEIMFETGKAPDKIVEEKGLVQVSDNNVLNTVIDEVIAENPESVEGYRSGKDKLFGFFVGQVMKKTGGKANPTLVNQLLKEKLSS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RS5_BURCH
Sequence: MAKMQAKVQADERDDGLREKMISVNRVTKVVKGGRILGFAALTVVGDGDGRIGMGKGKAKEVPVAVQKAMEQARRNMFKVPLKNGTLQHEVHGKHGASAVLLAPAKAGTGVIAGGPMRAVFDVMGVQNVVAKSHGSTNPYNLVRATLDGLRKQSTPADIAAKRGKSVEDILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RS8_XANC8
Sequence: MSMTDPIADLLVRIKNAAAVGKQTVKLPSSKIKVAIAQVLKDEGYITDLRVTATENNKSELEIVLKYFEGRPVIETLKRFSRSGLRQYRGKTELPKVLGGLGIAIISTSKGIMTDAQAREAGVGGEVLCFVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ASTE_SALAR
Sequence: MDNFLSLTLTGETPRVTQGKGADFRWRWLGHGLLELTPNAPVDRALILSAGIHGNETAPVEMLDKLLSALYIGSLSLTWRVLVVFGNPQALAAGKRYCNSDMNRMFGRRWQSFAESDETRRARELELSLETFFSYEQARIRWHLDLHTAIRGSHHLRFGILPQRDRPWDTDFLAWLGAAGLEALVFHQAPGGTFTHFSTEHFGALSCTLELGKALPFGQNDLAQFSVTSQALSALLSGLETSTSSSPPLRYRVVSQITRHSDNFALYMDAQTLNFTAFTKGTLLAEEGDKRVTVTHDVEYVLFPNPAVACGLRAGLMLERLP
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: YB9F_YEAST
Sequence: MSIDEAVARYRDVIGNLATGNLRRIVIQSEKLAQIIASSKGTVRFHHKTRSGKTVIYKCIKKALLSSVASLSSEFSSETDVQQFLHLNYIYQSHFQALSGQINKYCGMKKYYELKFAAIDYLETEVQTTGLTLSRFWVASLDEFIKKERWPDNGSNFQIFYKLMAEYSSWKWDSDDKRQLQFMYEFRMKLKECLVKFYENFDLQKSSDPLKELIIPWEKIVYVANCIDAFTGEQVRIDGAELIWTSKNLVFSSISSAVLRLNDLQNMFSAFRPYGEEALVQDFAHIRSLKWDSNDKVESLIRALIFNDMFPYFNKEQVDTKADGIFFLRLLRKNFKEHINDVKDFHIQVIKYLNSQFKNNYSTLMTSSKTQDRRKSHNMPSSILDDGNKIGMHVSPIDEYSHFIDNDEPLWRDKVYPKIYTNEQTPTPDASAIFDSHKIYAIISLLRYYLPEKRKFFRIYYLPSIFKRILYYGAKFAQLYFMEGCLERLVIESLQILEPSLVHAINNLIKSSIESLKNVTVTSDDKTSSGVIILSYKEFKSLSEVNKDFNEPFWPNQSIANSWPDFANKQLKRGQILQDAFAFHLFEIELPIIIDTTRNTHLKLVSNMCTTSILYLYNEVDSLSLTSIQEKLAVLPTSKRNEILLYNLNRLTKLKLLLLKENEKGQKFYAFNFKYKRDGQKTSLIRLI
What are the official names of this protein?
Uncharacterized protein YBR259W.
Protein: PANC_EXIS2
Sequence: MKIMQSVTQLREALAGQTSVGFIPTMGFLHEGHASLLEQARQENDIVVLSIFVNPTQFGPNEDLDRYPRDEQRDQQLAQAAGVDYLFYPTNDVMYPLDMARVTVRSGDDVLCGTSRPGHFDGVLTVVSKLFNIVQPTRAYFGLKDAQQLALIEGYVTDYFVPVEIKRCPIIREADGLAKSSRNVYLSETERKQAPGIQQALQQAKQALDAGTPLETVLEQTRASLHFEGTTIDYVEAVAYPTLGPVDATTDTILLAVAVQFESARLIDNLLYTRGA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_VIBCM
Sequence: MKPLTPRQQEVFDLIKSKIDETGMPPTRAEIAKELGFRSANAAEEHLKALARKQVIEMVPGASRGIRILVDNAANEEEAETGLPLIGRVAAGEPILAQEHVEAHYQVDPSMFRPQADFLLRVHGESMKNIGILDGDLLAVHKTQDVRNGQVVVARVEDDVTVKRLERKGSKVFLHAENEEFAPIEVDLAAQSLTIEGIAVGVIRNSTWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HIS3_BORBR
Sequence: MNTEPTWMAEVVFDENGLIPAIAQDAETGQILMVAWMNREALAETAATGRAVYWSRSRQRLWRKGEESGHAQDVHELRLDCDGDVILLKVHQNGGIACHTGRASCFYRRLEGTASQAEWITIDPVLKDPELIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFS_METJA
Sequence: MVKFCPKCNNLMLPKDGKLKCAVCGYEEETTAEGSKEYEYKEHLENKKEKITVIESEGLETLPTTRIECPKCGHNEAYWWLQQTRCADEPETRFYKCKKCGHTWREYD
What is the function of this protein?
Induces RNA cleavage activity in the RNA polymerase.  In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA.  The truncated RNAs are able to continue elongation.  Involved in transcriptional proofreading and fidelity.  Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end.  TFS is able to induce a cleavage resynthesis cycle in stalled elongation complexes (resulting from the next missing nucleotide or a reduced incorporation rate of a wrong nucleotide) preventing misincorporation and enabling proofreading in a post-incorporation manner.  Pausing of elongation complexes is the main determinant of TFS-induced RNA cleavage.
What are the official names of this protein?
Transcription factor S, Transcription elongation factor IIS/RNA polymerase subunit homolog, TFIIS/RPSU homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
Protein: RS7_SPHAL
Sequence: MARRRRPERREILPDPRFGDVVLSKFMNSVMLDGKKSVAESIVYGALEAVEARAKKEPLGVFHEALANIRPNIEVRSRRVGGATYQVPVEVRPDRAQALAIRWLITAARNRSETTMAARLSGELLDASNNRGNAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: DEOB_STAEQ
Sequence: MTTPFKRIHLIVMDSVGIGEGPDAAAFNDEGSHTLKHTLEGFKQKLPHLEQLGLGNIAPLPVVSKVTHPGAFYTKLSEASVGKDTMTGHWEIMGLNIMQPFKVYPNGFPEELVKEIESMTGRKVVANRPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQIAAHEDVIPLEELYEICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALKPFGRTVMNSLKDNGYDVIAIGKINDIYDGEGVTEAIRTKNNMDGMDQLIEVVKKDFEGISFLNLVDFDALYGHRRDKEGYAQAIKDFDLRLPELMNHLREDDLVIITADHGNDPIAKGTDHTREYIPLLMFSPKIKDYHELSQDTTFSSIGVTIADNFNVELPKYGKSYLKEMGVEHQ
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPHB_METBU
Sequence: MLDFVGLGLFDEKDISLKGLEKIHNADKVYVEFYTSILMGTDLEKMEMLYKKKITVLSREDVEQHAEDWLVDAKDSNVVFLTGGDTMVSTTHVDLRLRAADMGIKTTLIHGASIASAICGLSGLQNYRFGKSVTIPHPYVSNRGVRVVSQTPYDTIKNNIEAGLHTAVFLDIDKDKGYMTVNQAMEILLEVEGKLGEGVMVDRLAVGIARAGSPSPVVKADYIEALRDYYLGGPLHIVVIPAELHFVEAEALVKLAGAPEGILENID
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: 373L_IIV6
Sequence: MIEIIISTIFILYILLTKYKYETLKVIRTLMKNYKEIPLQNITLSENNEVTVEDKRIKIVTITIHGNKHMVKYKFNNKLFTALLPCTESEYQFHITTKNGIDVTENVIKFMGPNYDFYGVKIKVNEIGYDSLMFHRPGKEPTILKSDDYLPNNLSDYQWDFSLVGLNQNISPPPVGEETASNTVEENTMENILKETKNLSQNILIQKKTSISGYKTLDVKRKFVKRKFVKRINLNYSFLILLN
What are the official names of this protein?
Uncharacterized protein 373L.
Protein: RPOA_CHLL2
Sequence: MIYQMQMPAKIEVDEATHTDRFGRFVAQPLERGYGVTLGNVMRRALLASLPGTAITGLKIDGVFHEFSTINGVREDVPEIVLNLKKVRFRSNCKRNCKTSLVLNGQKEFTAGDIIAQEGEFEVLNKDLHIATVNEGATLKIDIFVGRGRGYLPSEENRPDGMPIGFIAIDAIFTPIRNVKFTVENTRVGQRTDYEKMILDVETDGSITPDDSISLAGKIINEHVTFFADFSPTEEEFTEEEFKQQDDEFENMRKLFNTKIEDLDLSVRSHNCLRLAEIDTIGDLVSRKEDELLNYKNFGKKSLTELKEQLEKFDLKFGMDITKYQMKG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL35_FUSNN
Sequence: MPKMKTHRGAKKRIKVTGTGKFVIKHSGKSHILTKKDRKRKNHLKKDAVVTETYKRHMQGLLPYGEGR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL24_MOUSE
Sequence: MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Cytoplasm.