PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_SPTNK
Sequence: MSNSAIPLNVVAVQEPRLELNNERTWVVVKGGQQVTYYPFPSTSFSSNQFNFICNPPSAQTVLDRLVFIQVPYDITFTANPSHAGITENLLQPGRDAFRAFPISSITNTLNATINGFPVNIELAQIIHALSRYHTPLKVKNGWMSMQPSFEDNYQSYRDADGANNNPLGVFTSAAGLSELPRGSYTMNVVTNTTTTARITGVLYEQVFLPPFLWDGEQAGGLANLTSLTFNWVLNNNLARIWSHSDITNDVSGNSTIGSMNISFQQPSMYLGFVTPRLNIPIPPRITYPYFKLSRYTTQFQNTLAPNASSTFKSNVVQLDSIPRKLYLFVKQSDNVIYQNLNNQITTPDVFLQINNLNLTWNNQQGILSGASSQNLYDFSVQNGYNKTWSEFNGVTQQFNGVSGQPTKVIGLEGGIVCLELGKDVGLRDDEAEGVIGNFNLQVQMTVTNTNQYVTVTPDMYIVAVYDGTLVISNTSAMASIGVASKEEVLNARITHGVSYNELQRIYGGDFFSSFKNFLGKVGNVAGKVNNFLKDSKIASSVLGAIPHPYAQVPGQILKNVGYGESHVGGGKKKGGVLIGGRQLTKAELRKELKM
What is the function of this protein?
May self assemble to form an icosahedral capsid.  Most abundant protein in the virion.
What are the official names of this protein?
Putative capsid protein V20.
What are the subcellular locations of this protein?
Virion.
Protein: LOX13_SOLTU
Sequence: MIGQITSGLFGGHDDSKKVKGTVVMMNKNVLDFTDLASSLTGKIFDVLGQKVSFQLISSVQGDPTNGLQGKHSNPAYLENSLFTLTPLTAGSETAFGVTFDWNEEFGVPGAFIIKNMHITEFFLKSLTLEDVPNHGKVHFVCNSWVYPSLNYKSDRIFFANQPYLPSDTPELLRKYRENELLTLRGDGTGKREAWDRIYDYDIYNDLGNPDQGKENVRTTLGGSAEYPYPRRGRTGRPPTRTDPKSESRIPLILSTDIYVPRDERFGHLKMSDFLTYALKSIVQFILPELHALFDGTPNEFDSFEDVLRLYEGGIKLPQGPLFKALTAAIPLEMIRELLRTDGEGILRFPTPLVIKDSKTAWRTDEEFAREMLAGTNPVIISRLQEFPPKSKLDPEAYGNQNSTITAEHIEDKLDGLTVDEAMNNNKLFILNHHDLLIPYLRRINTTITKTYASRTLLFLQDNGSLKPLAIELSLPHPDGDQFGVTSKVYTPSDQGVESSIWQLAKAYVAVNDSGVHQLISHWLNTHAVIEPFVIATNRQLSVLHPIHKLLYPHFRDTMNINALARQILINAAGVFESTVFQSKFALEMSAVVYKDWVFPDQALPADLVKRGVAVEDSSSPHGVRLLIEDYPYAVDGLEIWSAIKSWVTDYCSFYYGSDEEILKDNELQAWWKELREVGHGDKKNEPWWPEMETPQELIDSCTTIIWIASALHAAVNFGQYPYAGYLPNRATVSRRFMPEPGTPEYEELKKNPDKAFLKTITAQLQTLLGVSLVEILSRHTTDEIYLGQRESPEWTKDKEPLAAFDRFGKKLTDIEKQIIQRNGDNILTNRSGPVNAPYTLLFPTSEGGLTGKGIPNSVSI
What is the function of this protein?
Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure.
What are the official names of this protein?
Probable linoleate 9S-lipoxygenase 3.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRK_PENRO
Sequence: MHPDSQLETAVKNGFDPKSLYSTELTKVNEPARTILEQYSKIPAEKVLQHVKDLKDRAFEVFPYACIGQASFLELSIASSPCYPEMLDRVKKGDRLLDLGCAFGQELRQLIYDGAPSQNLYGTDLRPEFLELGLDLFLDRSFIKSHFIDADVLDDKSALVTQLTGELNIVYISLFLHVFDFETQIKVAKRVLDLLAPKAGSLIVCRVVACRDQAIGNATNARLPYYYHDLASWNRLWERVQEETGLKLKVDNWEQDDALAKKHPLEGIYMLGSSIRRE
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (PubMed:28529508).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (By similarity).  DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (By similarity).  The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (By similarity).  The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (By similarity).  The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A.  The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D.  The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F.  The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C.  Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (By similarity).
What are the official names of this protein?
Methyltransferase adrK, Andrastin A biosynthesis cluster protein K.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily.
Protein: ENO_HAEDU
Sequence: MAKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNNEIAQAIVGKEGCAQSEIDQTMIDLDGTENKSKFGANAILAVSLATAKAAAASKGLPLYAYIAELNGTPGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPIGAKTLREALRIGAEVFHNLAKVLKAKGLSTAVGDEGGFAPNLASNADALACIKEAVENAGYVLGKDITLAMDCASSEFYNKENGLYEMKGEGKSFTSQEFTHYLENLCKEYPIVSIEDGQDESDWDGFAYQTKILGDKVQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRIAKYNQLIRIEEALGEMAPFLGLKAIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CKX6_ORYSJ
Sequence: MAARCSIAFMVMASCLSVVVSGGLPGDLFAHSVASKLRVDRDTTARASSDFGRIVAAAPEAVLHPATPAEIAELVRFSASSPSPFPVAPRGQGHSARGQSLAPGGVVVDMRALAARRGRVNVSAGGAGAAPYVDAGGEQLWADVLRATLEHGLAPRVWTDYLRITVAGTLSNAGIGGQAFRHGPQIANVLELDVITGRGDMVTCSRDKEPDLFFAVLGGLGQFGIITRARIGLEPAPKRVRWVRLAYSDVVTFTRDQELLISKRASEAGFDYVEGQVQLNRTLTEGPKSTPFFSRFDIDRLAGLASESVSGVIYFIEGAMYYNESTTASVDQKLTSVLEQLSFDKGFVFTKDVSYVQFLDRVREEERILRSIGMWDVPHPWLNLFVPQSRILDFDTGVLKGVFVGANPVGVILMYPMNRNMWDDRMTAVSGNDDMFYVVGLLRSAVVPGDVERLERENEAVLAFCDNEGIGCKQYLPHYASQDGWRSHFGAKWSRVTELKVKYDPYGILSPGQRIFSSLTPMALVAM
What is the function of this protein?
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group.
What are the official names of this protein?
Cytokinin dehydrogenase 6, Cytokinin oxidase 6, OsCKX6.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: PURQ_NOCFA
Sequence: MSARIGVITFPGTLDDVDAVRAVRLAGAEAVNLWHADADLKQVDAVIVPGGFSYGDYLRAGAIARFAPVMGEVVRAAEQGMPVLGICNGFQVLCEAGLLPGALTRNEGLHFICRDQWLTVESVSTAWTSRYEPGAQILIPLKSGEGRYQAAPAVLDELEGEGRVVFRYSGDNPNGSQRGIAGISSANGRVVGLMPHPEHATEALTGPSDDGLGLFLSVLDTLVTA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_STAAR
Sequence: MSKVHVFDHPLIQHKLSYIRDVNTGTKEFRELVDEVGMLMAYEVTRDLELQDVDIETPVTKMTAKRLAGKKLAIVPILRAGLGMTDGILSLVPAARVGHIGLYRDPETLKAVEYFAKLPQDITERQIIVVDPMLATGASAIEAITSLKKRGAKNIRFMCLIAAPEGVEKMHEAHPDVDIYIAALDEKLNDKAYITPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SYL_STUS1
Sequence: MHEQYQPREIEAAAQSHWDSQKSFEVSEQPGKDTFYCLSMFPYPSGKLHMGHVRNYTIGDVIARYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKAQLKSLGLAIDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITAYADELLESLDELDGWPEQVKTMQRNWIGKSRGMEISFPYDVASIGNEGVMKVFTTRPDTLMGATYVAVAAEHPLATLAAQHNPELQAFIDECKRGGVAEADIATQEKKGLATSLRVQHPLTGELLPVWVANYVLMNYGEGAVMAVPAHDERDFEFASKYGLPIKPVVRTSAGDETPAPWQDAYGEHGQLINSGIYDGLDFEGAFDAIEVALQKKGLGQARTQFRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPEDQLPVVLPEDVVPDGAGSPLARMPEFYECTCPKCGAPAKRETDTMDTFVESSWYFARYASPNYDKGMVDPQAANHWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRTLENGGKDWFNPADVEVERDAKAKVIGARLKTDGLPVEIGGTEKMSKSKNNGVDPQAMIDAYGADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAHAHVSAGLPGALDVAALNDEQKAVRRAIHLAIKQASTDVGQHHKFNTAIAQVMTLMNVLEKAPTAGEQDRALLQEGLETVALLLAPITPHICHELWQQLGKPGAIIDAQWPKVDEAALVQDSLTLVVQVNGKLRGQIEVPASASREEVETAARGNENVLRFTEGLTIRKVIVVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: AUSC_EMENI
Sequence: MYASNKTYPSSRALPCLVEKVEAQHVDGAIRVRITTLEQKDWRQAKAAAVEAKYEAEREIQLRAHGNVKDIEITRESAFEHFATDPWAQHVGVDIEAQRERLLAEPGSRKILIIGAGFGGLLFAVRLIQTGRFTAEDITMIDSAAGFGGTWYWNRYPGLMCDTESYIYMPLLEETGYMPRNKYASGNEIREHAERIAQTYGLATRAMFRTVVEKLDWNEAEKVWTVAGSMLGIANNGQRDNMMSFQMVSQFTIMASGSFASPRVPDYPNIFDYKGKLFHTARWDYNYTGGSVENPKMLGLADKTVAIIGTGASAVQIVPQLAKYSNKLIVFQRTPAAVDARNNCPTDPVWWETETQAEGTGWQKRRQENFNAFTCNEKPLPSVNKVDDGWTRMPSFSILIGGPQGLDPDYVDRMRAVDMNRQEKIRARAHNIVQSEGSADLLTPWYPGWCKRPCFHDDYLSAFNLPNVELVDIRHNGISHFTANGLVANDIEYELDVIILSTGYTVPVTRASPSSRANIAVSGRNGTTMEAKWANGLATLHGVMTRDLPNLFFAGTSQAGACVNLVYALDQNATHVAYILANAFDRRPSDSARVIIEPTPGSEEAWAMQVLQRAAGFRGIAGCTPGYLNGYGMDASSLSPEQQINAARLAAWGEGIASYVRYLEAWRAKGDLNGIELTFFAKF
What is the function of this protein?
FAD-binding monooxygenase; part of the gene cluster A that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids (PubMed:22329759).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:22329759).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:22329759).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (PubMed:22329759).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (PubMed:22329759, PubMed:23865690).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (PubMed:22329759).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (PubMed:22329759).  Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol (PubMed:22329759).  Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation (PubMed:22234162, PubMed:22329759).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional (PubMed:29076725).
What are the official names of this protein?
FAD-binding monooxygenase ausC, Austinoid biosynthesis clusters protein C.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL22L_XENTR
Sequence: MAPSKDKKPKKAWSFTLDLTHPVEDGIFDSVNFEQFLKERIKVNGKTGNLGSIVHIGRLKSKITVSSEKKFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDDESESEE
What are the official names of this protein?
60S ribosomal protein L22-like 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
Protein: PSIE_KLEP3
Sequence: MSSVYRPLVNFIATAMQTVLNLGLLCLGIILIVFLGKETLHLADVLFTPEPTSKYRLVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLIIIDHESPMAVLIYSAAILILVITLWLCNSNRLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RA51D_ARATH
Sequence: MAPLKHLEKENPIIDACFQDFCASHGILTIEDFLLHDLYELTAFSQRQTNADRLKEGITLILSLIERQCRPLVNGLKLLEDLHRNKHTLSTGDKETDSLLQGGFREGQLTELVGPSSSGKTQFCMQAAASVAENHLGRVLYLDTGNSFSARRIAQFICSSSDATLGQKVMSRILCHTVYDIYTLFDTLQDLEITLRLQMNVNESRLRLLVVDSISSLITPILGGSGSQGRALMVAIGYLLKKLAHEHSIAILVTNHTVGAGGEGGKTKPALGETWKSIPHVRLSLSRDHKNSNCTISILKHTSLPSGQAAKTLTRKENQQCP
What is the function of this protein?
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
What are the official names of this protein?
DNA repair protein RAD51 homolog 4, AtRAD51D.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS9_HALH5
Sequence: MAQVQYYGTGRRKHSVARVRLVPGDGNIVINGRSLDEYFGLETLKLIVKQPLVETGTEGQYDVRVNVDGGGFTGQAGAIRHGIARALLQVDPEYRPSLKSAGFLTRDARMKERKKYGLKAARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ATN5_YEAST
Sequence: MSEGTVKENNNEEFNAYHTLTTEEAAEFIGTSLTEGLTQDESLRRLKAVGENTLGDDTKIDYKAMVLHQVCNAMIMVLVISMAISFAVRDWITGGVISFVIAVNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTIPADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVGTPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTITISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDLFQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQSNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFESIISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQLKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAPDLMDRPPNDSEVGIFTWEVIIDTFAYGIIMTGSCMASFTGSLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMHPDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAIAFTIAFWIGAELYKCGKRRYFKTQRAHNSENDLERSSKHDPFEAYSTSTTLQSEINISVKH
What is the function of this protein?
Catalyzes the hydrolysis of ATP coupled with the export of sodium and potassium from the cell (By similarity).  May export potassium less efficiently (PubMed:22329368).  May transport other cations such as lithium (By similarity).  Sodium/potassium efflux ATPases are involved in salt tolerance and maintaining the membrane potential across the plasma membrane in high salinity (Na+) or alkaline (K+) environments (By similarity).
What are the official names of this protein?
Sodium/potassium exporting P-type ATPase 5.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_PSEPF
Sequence: MAFLALGINHKTASVDVRERVAFTPEQLVEALQQLCRLTDSREAAILSTCNRSELYIEQDQLSADIVLRWLADYHHLSLDELRASAYVHEDDAAVRHMMRVASGLDSLVLGEPQILGQMKSAYAVAREAGTIGPLLGRLFQATFNAAKQVRTDTAIGENPVSVAFAAVSLAKQIFSDLQRSQALLIGAGETITLVARHLHELGVKRIVVANRTLERASLLAEQFGAHAVLLSDIPAELVRSDIVISSTASQLPILGKGAVESALKLRKHKPIFMVDIAVPRDIEPEVGELDDVYLYSVDDLHEVVAENLKSRQGAAQAAEEMVSVGADDFMVRLRELAAVDVLKAYRQQSERLRDEELQKALRLLANGGNAEDVLGQLARGLTNKLLHAPSVQLKKLSAEGRLDALAMAQELFALEGSPDSFSDKKPQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: GLYT8_ARATH
Sequence: MASSDSSYSRKFLLITFLPLSLACLAFLLQWRSGVNDSVTQWFDDNYPFPGMATVSEKRSLRSDSSCVSLLGQSRTQAFPYLRDLKLDHKPDLKPRICITTSTSAGLEQTLPWIFYHKVIGVETFYLFVEGTAASPNVSRVLETIPGVNVIYRTRELEEEQAKSRIWNETWLEKFFYKPCNYELFVKQNLNMEMAITMARDAGMDWILHLDTDELVHPSGTREYSLRNLLRDVPADVDEVIFTNYESSVERDDIKEPFTEVSMFKKNFKHLPREVYYGNYKEATRGNPNYFLTYANGKSAARIQDHLRPNGAHRWHNYKTYPNIKELDEAAILHYTYSKFSDLTSRRDRCGCKPTKKDVKRCFMLDFDRAAFIIASTSTSEEMLQWYRERVVWTDDNLILKLLRKGILTRIYAPMVIIQELREAGVFSSVVTSAHMSLSKNRSNSSTSSNY
What is the function of this protein?
Involved in the coordination between cell elongation and cellulose synthesis by promoting the expression of genes involved in cell elongation and cellulose synthesis.  Acts as a regulator of plasmodesmatal permeability.  Maybe a glycosyltransferase.
What are the official names of this protein?
Glycosyltransferase-like At2g41451.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 92 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cytoplasm. Cell membrane.
Protein: SDEA_EMENI
Sequence: MASHTKDALLSRRYIEGQIAAGKHIIIFDDRVLKVDSWIKFHPGGDKSIKHMVGQDATDEINALHSVEARQRMLAFQIGRIQGPWVNFLPPIQGGKFRHYDENADSEEDDTSGQSQPPSPIFDAVDAAPGVRRQYASSETSVSTPASESSEPKPFFLDARTREEIVLDTAKYPSLDAKTQQDIKRRYRELNKRIEAEGLYDCNYFSYFIEACRYTLFAGLSYFFLRLGWYSVSAVFLGCFWHQLVFSAHDAGHIAITHNYQVDSIIGILIADFLGGLSLGWWKRSHNVHHIVTNEPEHDPDIEHMPFFAISHRFFMNLRSTYYDRVMYFDAFSNFMLKYQHYLYYPILLFGRFNLYRLSWEYLILGQGPRKGPAWWHRWFEIAGQIFFWIWFGYGVLYCSIPTWGSRLSFLFISHMVTAPVHVQITLSHFAMSTADLGVQESFPQKMLRTTMDVDCPTWLDFFHGGLQFQAIHHLYPRIPRHNLRRTQKLVLEFCRDTGIPYALFTFTDGNKEVIGRLGDIAKQVRILEECRKSCAQQGVFSNHH
What is the function of this protein?
Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides (PubMed:27479571).  Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis (By similarity).  Plays an important role in conidiation (PubMed:27479571).
What are the official names of this protein?
Delta 8-(E)-sphingolipid desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
Protein: TNFA_PANTR
Sequence: MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAGSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: RL32_AERS4
Sequence: MAVQQNRKTRAKRGMRRSHDALTSAALTVDQTSGEIHRRHHVTADGFYRGKKVIA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SPI1_HUMAN
Sequence: MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHSEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGRGGLAERRHPPH
What is the function of this protein?
Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites.  Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions (PubMed:23658224, PubMed:33951726).  Transcriptionally activates genes important for myeloid and lymphoid lineages, such as CSF1R (By similarity).  Transcriptional activation from certain promoters, possibly containing low affinity binding sites, is achieved cooperatively with other transcription factors.  FCER1A transactivation is achieved in cooperation with GATA1 (By similarity).  May be particularly important for the pro- to pre-B cell transition (PubMed:33951726).  Binds (via the ETS domain) onto the purine-rich DNA core sequence 5'-GAGGAA-3', also known as the PU-box (PubMed:33951726).  In vitro can bind RNA and interfere with pre-mRNA splicing (By similarity).
What are the official names of this protein?
Transcription factor PU.1, 31 kDa-transforming protein.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OPGD_XANCP
Sequence: MQRRHFLKNAAAALAALGLPALPPWALAAKAVGLRRLGQPQPFDYAWLKGQARALAKAPYKSHKQVLPGPLESLNWDQYQSIRYRQDHALWADGNGKFQAKFFHLGLYFHTPVHIYDIVDGKAQQLAYDPAAFDYGRSGLGGKQLPKDLGFAGFRLNTRKDTDRDFSAFLGASYFRAVGKEGQYGQSARGLAIDTGTGGPEEFPDFIAYYLEQPADDSDTVVVYGLLDSPSVSGAYRFAITNGEVLVMDIDSALYPRKAIERLGIGPCTSMYQTGENDRRMDWDWRPEIHDTDGLAMWTGGGEWIWRPLCNPPHLRFNMFVDENPRGFGLLQRDRNFDHYQDDGVFYEKRPCLWVEPKSGWGKGSVQLVEIPTVDETFDNIVAFWNPQAKPQPGQELLMGYRLYWGAHPPASSPLAHCVATRTGLGGIVGQKRSHFSWRFAVDFAGGELAALAKDPKAKVEAVLQVSRGTTEIVSARPLHELKGYRAMFDLVPPDEGTQQIDIRLFLRANGKPLTETWLYQWTPPPASERKIY
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: XNI_SHIF8
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKADRPPMPEELHDEMPALRAAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.