PharMolix/UniProtQA huggingface dataset:
Protein: GLYCO_DMSVA
Sequence: MAHYELHVLFVHSWMLALILITTLVWLAASQKAFTPDLVFPEMNRNSSWSVANYGEILCPTSFQSYDPKKHQILTRVLVERPSLNTDTKVEGYTCHKVKYETICDMPWYFSPTISHSISPLRVKESECKDAIAEHQLGTHVPLSFPPEDCSWNSVNTKEYEDIIVKEHPVMLDPYTNNYVDAIFPGGISSPGMGGTIHDDMMWVSKDLAVSPECSGWQRSMGLIYSSRLYGEREPMLEVGSIHIEGHRDKNLTLACRISFCGEIGVRFHDGEWMKVSVNLDHPNSVTFQVTDFPPCPPGTTIQTAVVENINPEIQELTVNMMYRLKCQETISKMVSGLPTSALDLSYLIQVQEGPGIVYKREKGILYQSVGMYQYIDTVTLNKEENQLGENSRGQKVFWTEWSDSPTRPGLQEGINGIVKYEGQVRVPLGMSLRLEAATELMWGHPVHTVSHPILHVISNHTEQSVTTWNRGVNSTNLIGLATRSISGFYDNLKLYLILALIFVSLIALVVLDVIPFKYILFVLCPPLLLCRFIKCSRRKPETRDRYHVEYNRPGQVSSAF
What is the function of this protein?
In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane.
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host membrane; Single-pass type I membrane protein.
Protein: URE3_STAAT
Sequence: MHFTQREQDKLMIVVAAEVARRRKARGLKLNHPEALALISDELLEGARDGKTVAELMSYGRQILNKEDVMDGVEHMITDIEIEATFPDGTKLITVHHPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_AGRVS
Sequence: MNTATSQPRRLTILGSTGSIGTNTLDVIRQMGGRDRFDIMALTGHGNVALLAEQALVTGARLAVTSDENQYIALKDLLSGSGIDVAAGSSGLQEAACLEADWVMAAIVGTAGLQPTLTAAARGADIALANKECLVSAGELFIETVRKGGGKIIPVDSEHSAIFQCLDENHRDTLERIVLTASGGPFRTFTRQQMADVSVQTARAHPNWSMGLKVSIGSASMFNKALEMIEAKHLFDLTPDQIEVIVHPQSIIHSMVGYSDGSVLAQLGVPDMRTAIGYALSYPKRAALDVDRLDFTKLARLDFEAPDLDRFPAIRLARTALERGGLQGAVLNAAEECAFEAFVEEKIGFLAMADVVEDVMDHLSGLAPATVIADVFAADAQARRRAQEVILNQGRTR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: PSRP_KLEP7
Sequence: MESAVDRHVFYISDGTAITAEVLGHAVMSQFPVAISSVTLPFVENISRARAVKEQIDAICQQTGIRPLVFYSIVIPEIRDIILQSEGFCQDIVQALVAPLQQELNLDPTPVAHRTHGLNPGNLIKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQYGIRAANYPFIADDMDNLVLPASLKPLQHKMFGLTINPERLAAIREERRENSRYASLRQCRMEVTEVEALYRKNKIPCLNSTNYSVEEIATKIMDIMGLNRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: UBP38_HUMAN
Sequence: MDKILEGLVSSSHPLPLKRVIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLHQGYHSLDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPQLCARLSDLLTDFVQCIPKGKLSITFCQQLVRTIGHFQCVSTQERELREYVSQVTKVSNLLQNIWKAEPATLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLIVPHVVNLVHSFKNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAWTSQSNSLASCLSRLSGKSETGKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILKVQASHKPSEILECSETSLQEVASKAAVLTETPRTSDGEKTLIEKMFGGKLRTHIRCLNCRSTSQKVEAFTDLSLAFCPSSSLENMSVQDPASSPSIQDGGLMQASVPGPSEEPVVYNPTTAAFICDSLVNEKTIGSPPNEFYCSENTSVPNESNKILVNKDVPQKPGGETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTDEASCTKLVPYLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHLLGRDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQHSTNGLSGNNPTSGLWINGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF
What is the function of this protein?
Deubiquitinating enzyme exhibiting a preference towards 'Lys-63'-linked ubiquitin chains.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 38, Deubiquitinating enzyme 38, HP43.8KD, Ubiquitin thioesterase 38, Ubiquitin-specific-processing protease 38.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: RL20_BACAN
Sequence: MPRVKGGTVTRQRRKKVIKLAKGYYGSKNTLFKVANQQVMKSLMYAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKNAGIEVNRKMLADLAVHDEKAFAELATVAKNNIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: DRS1_PHYBI
Sequence: MDILKKSLFLVLFLGLVSLSICEEEKRENEDEEKQDDEQSEMKRAMWKDVLKKIGTVALHAGKAALGAVADTISQGEQ
What is the function of this protein?
Possesses a potent antimicrobial activity against bacteria, fungi and protozoa.  Probably acts by disturbing membrane functions with its amphipathic structure.
What are the official names of this protein?
Dermaseptin-B1, DRS-B1, Dermaseptin BI.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS11_BOVIN
Sequence: MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: KDTA_CHLTR
Sequence: MIRRWLTSRLYDAFLVCAFFVSAPRIFYKVFFHGKYIDSWKIRFGVQKPFVKGEGPLVWFHGASVGEVSLLAPLLNRWREEFPEWRFVVTTCSEAGVHTARRLYESLGATVFVLPLDLSCIIKSVVRKLAPDIVIFSEGDCWLHFLTESKRLGAKAFLINGKLSEHSCKRFSFLKRLGRNYFAPLDLLILQDELYKQRFMQIGISSDKIHVTGNMKTFIESSLATNRRDFWRAKLQISSQDRLIVLGSMHPKDVEVWAEVVSHFHNSSTKILWVPRHLEKLKEHAKLLEKAGILFGLWSQGASFRQYNSLIMDAMGVLKDIYSAADIAFVGGTFDPSVGGHNLLEPLQKEVPLMFGPYIYSQSVLAEKLREKEAGLSVNKETLLDVVTDLLQNEKNRQAYIEKGKSFLKQEENSFQQTWEILKSQITCMKI
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Catalyzes the transfer of three 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.  Thus generates the genus-specific LPS epitope of Chlamydia, composed of the trisaccharide alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid transferase, Kdo transferase, Kdo(2)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Kdo-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Trifunctional Kdo transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: NSP11_WTVNJ
Sequence: MSNKESNVALQTLRVTKDMKDFLSHRIVGEPPANIKIEYQKIHRYRTCVCPSTGHISELCPSGDLILSLGAHRNVIAAATVYDVVKNKTKSTTSKAGTSSTLSSLGLSGFQKPKIGSKNKKTMFSKQNNSTNESDESEGEEGSSLNDLPKSDLINAIMELASQGRNNSKGKGRRGGKR
What is the function of this protein?
Constituent of viral factories.  Binds to ssRNA and dsRNA (By similarity).
What are the official names of this protein?
RNA-binding protein, Non-structural protein 12, Pns12.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus RNA-binding protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Constituent of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: ILVD_CAMC5
Sequence: MRSDVIKKGYTRAPHRSLLRATGLKDEDFSKPFIGVANSFIEIIPGHFFLNKYAEILKDEIRKNGCVPFEFNTIGVDDGIAMGHGGMLYSLPSREIIANSIETVMNAHALDALVCMPNCDKIVPGMVMGALRVNVPTIFVSGGPMRKGYTKSGQPIDLATAFEAVGKFETKEISEEELKEIECNACPSGGSCSGMFTANSMNTLCEAMGIALSGNGTILALTKEREELIRRAGRRICEIALDERFKIRNILNEKAVRNALVVDMAMGGSSNTVLHMLAISREAGVNLQISQLNKISQNIAHIAKISPSLPNVHMEDIGRAGGMNAVIKEISRRDNGMLHLENLTVSGETLGERVGLSEIKDESVIHKVENAYSKVGGLAILFGNLAEQGCVIKTAGIVGERKFSGKAVCFNSQDEAIAGISSGKVGKGDVVVIRYEGPRGGPGMQEMLSPTSLIMGRGLGADVALITDGRFSGATRGLSIGHISPEAAEGGMIGLLRDGDIIDIDVDTYSINVRLSEAETLKRKAEFKPVQKELKGKWLRQYQRLVTNASNGAILEA
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: DEP1_CAEEL
Sequence: MIRWKYELHSLIWLFLVLHLSKCQSDSLTTSAEQHELFAIKKDSLSPWSQILVSLPRRHPLYQSFAAKIQDVTENISDEVRDSNKTFVSSDDAPYSIRIHALRAGHRYSIAIHGQKDGSTSLIKEESVVMDPRAPDFRSMDSDIQVAEHNITMRTIKNDSYLQDSFSIEYRQINPDKKFPVLQILDIPEQKNLEFYLGNLNSGFDYSVRVIAHKDGMSSRPWISTLTTKPSPLKEVNINQNAGSCVEVSWQNDEFSGADFYTIQYSLQSTPNNSTNMTIPSTESSISICDSMLQGEAYQIIATVQKGGQVSEPLITKFQLRPLPPIDFRVRADLKRGKYKLLAELPTSSKIDKCQITVAGDEAERSVNYANIEQTKSGHKICWFNFALSPGERFDFSISSMANESASQKLQKSIVLTPAFDFNAFGLTLQESNGGIELIWPKSEVFMTRVKDIWNKVVGAESLLNMRITPIGNNDETDKTLKFETSPKNIDPVFAKNLVKGACYRVQLFTVTKTGIISETRHNETIRMSSPAVNVSLESVTRSSATLRIVFSTHHDSTSISNCQMHIVVRDMNGKSVFDKRMQLTATFAPLLNLDGLSPFHKYTVNTQIICGSGSSETPQCPAATRTMRQLSFSTRQDKPAAVQDLKVEPLNSYSVMLTWLPPALPNGILTHYAVNVTKIGSDETRTIDVGVSSNRSDHTVQVVIDELFGGHTYSFSVRAVTEAGFGENSPVVPTVSMPLMAPPVPTVAPMIMKESVGSHNMIVRFPTTMFDNRNGEIKQFAIIVSETTADESINRWIESDNGTYTWQQVQRFDVWPSYVAKLQDIQKVKQDVDVSIFEELGEDETCLEVRADRICNGPLRSASKYRVRIRLFTSPTLFTDSPPSQVMTTGSATPAIPLLTVVAVLIVIAFVGIVGTIFLFFWNRTKKARLAAAAFKNGPSKEKESQWEALKMMMAERAADCLAKLGLDATTPPPSSTTSSNSPTSTSTTMTDCGSNPHLGAPNAGGHRRTRSLRERTGVEHRLERLSSGPVHRTPLYTVVTGANTNKSRPVRIEDFADHVRLMSADSDFRFSEEYDMMRNVGVGQSVAASELPINRPKNRFTNIPSYDHSRVKLSNPNNIEGGDYINANYVPGFSSRREFIAAQGPLPTTRDHFWQMTWEQQCPAIIALTKCVEKGRDKCHQYWPDHENVPVLYGDIEVTIVAEKEFDEFVIRDIRLEKSGPDGRVTRFVRHWHYMAWPDFGAPSHPNGIIQFSRMFRHHLPHSPHNAPTIVHCSAGVGRSGTFISIDRLLQSSSFGDPIDVFGTVCEMRYERCQMVQNEQQYIFIHYCILQVLQGSSPSPTSTSTGAHHNAGFVQDGQMIVESGF
What is the function of this protein?
Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system (PubMed:15901674).  By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5. p and P7. p (PubMed:15901674).  Similarly, may prevent duct cell fate in ABpr precursor (PubMed:15901674).  Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down-stream effects including the negative regulation of let-23 signaling and vulval induction (PubMed:28135265).  In particular, by dephosphorylating pat-3, promotes the recruitment (by unphosphorylated pat-3) of the cytoplasmic adapter protein tln-1 to the plasma membrane of secondary vulval precursor cells (PubMed:28135265).  This promotes the linking of focal adhesion sites to the F-actin cytoskeleton, and also acts to restrict the mobility of the let-23 receptor on the plasma membrane of vulval cells thereby attenuating let-23 signaling (PubMed:28135265).
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase dep-1, Density-enhanced phosphatase homolog 1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Note=Localizes in intracellular punctate structures in vulva cell precursors which partially colocalize with let-23.
Protein: ATG32_YEAS6
Sequence: MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSQGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL
What is the function of this protein?
Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria.  Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Recruits ATG11 to the surface of mitochondria.  Promotes also autophagy-dependent peroxisome degradation (By similarity).
What are the official names of this protein?
Autophagy-related protein 32, Extracellular mutant protein 37.
What is the protein family that this protein belongs to?
Belongs to the ATG32 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Vacuole membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass membrane protein. Note=Is recruited to the preautophagosomal structure during mitophagy and imported into the vacuole along with mitochondria during starvation.
Protein: SELA_SERP5
Sequence: MSTESQHLYSQLPAIDRLLRDPAIEPLVAQHGQTLISELLRQLQLQARETIKQHQRLPDWCADWPQALGARLAQQQRPSLAPVFNLSGTVLHTNLGRALLAQPAIEAVTRSMGAAVTLEYDLDGAGRGHRDRAVADLLCQLTGAEDACIVNNNAAAVLLMLAAIAPGKQVVVSRGELVEIGGAFRIPDVMRQAGCQLVEVGTTNRTHLKDYRNAINDQTGLLMKVHTSNYSIQGFTAAVDEAELAQLGAEHGLPTATDLGSGSLIDMAQYGLPAEPMPQRLLAAGVDLVTFSGDKLLGGPQAGIIVGKKALIARLQQHPLKRALRVGKLTLAALEATLRLYQQPELLGQQLPTLRLLTRPQQAMQAAAERLLQVLTPQFTGHFQLRAEPCWSQIGSGSLPVDRLPSYALTFTPQDGRGATLEALAERWRALPQPVIGRINDGRLWLDLRCLEQEDALIEALSA
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM09_MOUSE
Sequence: MAASVAPGVRTLWWAGAAWLRQGGIRELFRPRIEGSTPGRDFSLSHYQSTVIVERWWKVPLAGEGRKPHLHRRHRVYKLVEDTKHRPKDNLELILTQSVDEIGVRGDLVSVKKSVGRNKLLSQGLAVYASPENRKLFEEEKSLRREGKLEKIQTKAGEATVKFLRSCHLEVGMKNNVKWELNPEIVARHFFKNLGVVVAPHALRLPEEPITRWGEYWCDVTVNGLDTVRVPMSVVLFQKPKTKRYKHWLAQQAAKSVAPTNPQAV
What are the official names of this protein?
39S ribosomal protein L9, mitochondrial, L9mt, MRP-L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y2056_BDEBA
Sequence: MPNFQKFETFDKLTTVPCPYAPDCGGCQHIGVPYGHQAQNKINDLSGLFTAAEVAFPKPLKVLSAGPAHLRDRLDFSLQDGRLGLYRTDRHEILDIEVCAQLSPALQGWLSEFRKIQWPFKRGSFRLRVGPEGQRGLWIDLANVDIKTLLDEQNILRSLQQQAFVEIGQRRKVPVWTGNEFKLRDPEHHVWFQSWMNDIPVNLYCQVASFTQPSHTANKIICDVIYDWVKRYKAQRLIEFGSGIGNLTFPALAGAESVLACEIDELSLQGLERSLNELPASMSHLKDRVTIYRRDFQKKLTQDFSQFDGVLANPPRSGLMGFLNPLKSLAPEQRPEFFIYMSCYPESMARDLVTLQECGYRMQEVYIVDQFPQTDHYEVLGLLQREKA
What are the official names of this protein?
Uncharacterized RNA methyltransferase Bd2056.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: RL31_RICFE
Sequence: MKSGIHPEYKKFLIKVESDVFETMSTHPTGEILMDVDFRKHPAWNKDSGNVVNQSNKSVSDFNKRFSGLSFGGKKEAS
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ASPD_META3
Sequence: MLKIGIIGCGTIATMIAKAINYKKINGTIVALYDKHNDKSQDLNKLTNAKICDSIDKLVKEELDIVIECASIKSVEEVATKSLNHKKNVVIMSVGALADKNLFSKLYKIANDNEKKIFVPSGAIAGVDAIKTASIGRIDEVSLITTKPVYGLEDALKNKGIDTTNISEPTVVFEGTVFDAIKEFPQNINVSVVLSIASKIPAKVKIVADPSATSNKHEIIVKGSIGTIKTVVENNPCKDNPKTSALAAYSVIRLLKDLSEPIIVGT
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: APBE1_KLEP3
Sequence: MDMTFFRAALLGACVLLSGCDSATTPASPASTATVLDGKTMGTFWRVSVIGVDEAKAEALRAKVQAQLDADDRLLSTWKNDSALMRFNHAADTRPWPVSEAMVDIVTLSLRIGAKTHGAMDITVGPLVNLWGFGPDKQPVTTPDAQAIAAAKARTGLQHLQVINQSGRQFLQKDIPDLFVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALVSRGMNGEGKPWRVAIQKPTDRENAVQAIVDINGHGISTSGSYRNYYELDGKRISHVIDPQTGQPITHKLVSVTVIAPTALEADGWDTGLMVLGPEKAQQVVREQGLAVYMIVKEGEGFKTWMSPQFRTFLVGEKN
What is the function of this protein?
Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein such as NqrB and NqrC, two subunits of the NQR complex.
What are the official names of this protein?
FAD:protein FMN transferase, Flavin transferase.
What is the protein family that this protein belongs to?
Belongs to the ApbE family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor; Periplasmic side.
Protein: MEPA_ECO57
Sequence: MNKTAIALLALLASSVSLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRRTSAQLLRPQALDLVSRDGKHVVSTLWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YTM1_CANGA
Sequence: MSTDTSQVKVKFFTREKDESLHVDDVPMYAPISLKRYGLSEIVNHLLESETPIPFDFLIDGELLRTSLQEYLTKKGLSSETTLTVEYTRAVLPPSFLANFNNDDWVSALDVSDDFRHIYSGSYDGVVRTWNMSGKVEKQYSGHTGAVKAVKYISNTRIVSAGNDRSLRLWKTKNDDGSVSNNTGDENDEENIEDGKTLAILEGHKAPVVSLDVASNSRILSASYDNTVALWSTIYKEMTAIDHLEEIQNPNNKISTAAKKRRKLTLKDGTIRRRAPLSLLESHTGPVEQVIFDHGDNTVGYSVSQDHTIKTWDLVTARCIDTKTTSYPLLSIAQMPTLNLLACGSSVRHITLHDPRVSSSAKITQKQLVGHKNFVVGLDTCSENEYLLCSASHDGTVKVWDVRSTSPMYTITRQDPTVEKGVNDKVFAVKWAKSIGIISGGQDKKIQINKGDNIFKN
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein YTM1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: HIS7_SYNPW
Sequence: MMRTGEIHRVTGETDVQVRLNLDGSGQCQASTGVAFLDHMLQQISSHGLIDLEISARGDTHIDDHHTNEDVGIAVGQALAQALGDRRGIHRFGHFLAPLDEALVQVALDCSGRPHLSYSLSIPSQKIGTYDTELVKEFFVAVVNNSGLTLHIRQLDGANSHHIVEACFKAFARALRQATEIDPRRADAVPSSKGVLEQAGMN
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPT53_YEAST
Sequence: MDKHTAAIPTLTIKVVLLGESAVGKSSIVLRFVSDDFKESKEPTIGAAFLTKRITRDGKVIKFEIWDTAGQERFAPLAPMYYRNAQAALVVFDVTNEGSFYKAQNWVEELHEKVGHDIVIALVGNKMDLLNNDDENENRAMKAPAVQNLCERENLLYFEASAKTGENIYQIFQTLGEKVPCPEQNTRQSSTHDRTITDNQRIDLESTTVESTRETGGCNC
What is the function of this protein?
Required for transport in the endocytic pathway and for correct sorting of the vacuolar hydrolases suggesting a possible intersection of the endocytic with the vacuolar sorting pathway.
What are the official names of this protein?
GTP-binding protein YPT53.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: CODY_CLOBK
Sequence: MSSLLDKTRMLNRILQKSGTEPVDFEDICDLLSDVLACNVYIISRKGKILGSKFYSGFECEEVREVVLKENRFPDFYNNKLLNVNETLSNSPNHDKCVFDNLKDCSINNKLSTIVPINGNRERLGTLLLARFDKEFTDEDLILAEYSATIIGLEILRSKQDQIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGTEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKGTHIRILNDKLLEELKKIK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_CUPMC
Sequence: MAKRDYYEVLGVGKNASDDEIKKAYRKLAMKHHPDRNPDNKEAEEKFKEVKEAYEMLSDPEKKAAYDQYGHAGVDPNMAGGFGGGGFGGGGFAEAFGDIFGDIFGQAAGGGRRGGGPQAYRGADLRYSMEISLEQAAHGHEAQIRVPHWDDCEHCHGNGAEPGSSVETCPTCNGVGQVRVSQGFFTMQQTCPKCHGSGKFIPKPCTKCHGQGKLKSQKTLEVKIPAGIDEGMRIRSSGNGEPGINGGPPGDLYVEVHIKQHPVFERDGDDLHCQMPISFATAALGGDIEVPTLGGRASFPVPEGTQAGKTFRLRGKGIKGVRSGYPGDLYVHVNVETPVKLTEAQKDILRQFDRSVHEGGSRHSPQEQSWLDKVKSFFS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.