PharMolix/UniProtQA huggingface dataset:
Protein: F16PC_FUSNN
Sequence: MNTEIKYLELLSKTFKNIAETSTEIINLQAIMNLPKGTEHFMTDIHGEYEAFNHVLRNGSGTIRNKIEEAYGNKLTENEKKELASIIYYPKEKVELMQNKDNFNIDRWMITIIYRLIEVCKVVCSKYTRSKVRKAMTKDFEYILQELLYEKKELANKKEYFDSIVDTIISIDRGKEFIIAICNLIQRLNIDHLHIVGDIYDRGPFPHLIMDTLAEYSNLDIQWGNHDILWIGAALGNKACIANVIRICCRYNNNDILEEAYGINLLPFATFAMKYYGDDPCKRFRAKEGVDSDLIAQMHKAMSIIQFKVEGLYSERNPELEMSSRESLKHINYEKGTINLNGVEYPLNDTNFPTVNPENPLELLEEEAELLDKLQASFLGSEKLQKHMQLLFAKGGMYLKYNSNLLFHACIPMEPNGEFSELFVEDGYYKGKALMDKIDNIVRQAYYDRKNVEVNKKHRDFIWYLWAGRLSPLFGKDVMKTFERYFIDDKTTHKEIKNPYHKLINDEKVCDKIFEEFGLNPRTSHIINGHIPVKVKEGESPVKANGKLLIIDGGFSRAYQSTTGIAGYTLTYNSYGMKLASHLKFISKEAAIKDGTDMISSHIIVETKSKRMKVKDTDIGKSIQTQINDLKKLLKAYRIGLIKSN
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: HICB_ECOLI
Sequence: MRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALLTAFDFYFEDNELIPLPSPLNSHDHFIEVPLSVASKVLLLNAFLQSEITQQELARRIGKPKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Functions as an mRNA interferase antitoxin; overexpression prevents HicA-mediated cessation of cell growth and inhibition of cell proliferation.
What are the official names of this protein?
Antitoxin HicB.
What is the protein family that this protein belongs to?
Belongs to the HicB antitoxin family.
Protein: DGTP_ECO5E
Sequence: MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAVLRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRSPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: CCA_VIBCM
Sequence: MQIYLVGGAVRDQLLQLPVYDRDWVVVGSSPQAMLAAGFQAVGKDFPVFLHPNSKEEHALARTERKTSVGYTGFACHYAPDVTLEEDLLRRDLTINAMAQDNSGQLIDPYGGQRDLAAKVLRHVSPAFVEDPLRVLRVARFAAKLHHLGFTVAEETMQLMAKIAQSGELQHLTAERVWQEWHKSLSAHHPEMFLQVLRDCGALAVVLPEIDRLFGVPQPEKWHPEIDTGIHTLMVAKQAAQLSDSLLVRFAAQVHDLGKGVTPPSEWPRHKLHCHTGLNIIESLCERIRVPNEFRDLALAVCAQHSNIHRADELKPTTKLKVLGLLDVWRKPERLEQVLLCCEADHRGRLGLESEPYPQREIFLRAYQAALGVAVQAVIADGFQGKHIKEELDKRRVSAIEAL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PEBB_PROM3
Sequence: MKPLRLSSLDPVRMPEWRWAPFLSHAINALIPLKPEPYPVAPEFLQREGKTGSKSQPIKVTTCTWACRTKKFRQVRAACVEAGSSASVLNFVINPYHTFDLPFFGADLVTLPSGHLLALDLQPAITSDERHTKQVWERLMPIFEQWRVRLPEGGPIPEEAKPYFSPGFLWTRLHLGSEGNQLIDEVIMPAFRDYLNLYLDLVEMAEEVSPQRAFKLLEGQKRYLSYRGKKDPARAMLARFHGHQWTESYIHNVLFDL
What is the function of this protein?
Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin.
What are the official names of this protein?
Phycoerythrobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: ACH1_NEUCR
Sequence: MASPIASAALRARVKRPSMLKKLCNPEDMLQHFPNGAYIGWSGFTGVGYPKKVPTMLADHVEKNGLQGQLKYSLFVGASAGAETENRWAALDMIARRAPHQVGKNIAKGINEGRINFFDKHLSMFPVDLVYGYYTKDRQNKNLDVVCVEATEIKEDGSIVLGASVGATPELIQMADKVIIEVNTAIPSFDGLHDITFSDLPPNRKPYLIQQCRDRIGTTSVPVDPEKVVGIIECTTPDQTLPNSPADETATAIAGHLIEFFEHEVAHGRLPKNLLPLQSGIGNIANAVIGGLETSNFKNLNVWTEVIQDTFLDLFDSGKLDFATATSIRFSPTGFERFYKNWDNYYDKLLLRSQSVSNAPEIIRRLGVIGMNTPVEVDIYAHANSTNVMGSRMLNGLGGSADFLRNSKYSIMHTPSTRPSKTDAHGVSCIVPMCTHVDQTEHDLDVIVTENGLADVRGLSPRERARVIIDKCAHDVYKPILKAYFEKAEFECLRKGMGHEPHLLFNSFDMHKALVEEGSMAKVKF
What is the function of this protein?
Required for utilization of acetate.
What are the official names of this protein?
Acetyl-CoA hydrolase, Acetate utilization protein, Acetyl-CoA deacylase, Acetyl-CoA acylase.
What is the protein family that this protein belongs to?
Belongs to the acetyl-CoA hydrolase/transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2B2_BUNFA
Sequence: MNPAHLLVLLAVCVSLLAAANIPPQSLNLLQFKNMIECAGTRTWMAYVKYGCYCGPGGTGTPLDELDRCCQTHDQCYDNAKKFGNCIPYFKTYVYTCNKPDITCTGAKGSCGRTVCDCDRAAALCFAAAPYNLANFGINKETHCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Basic phospholipase A2 2, svPLA2, KBf II, KBf-2, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 isozyme II.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BIRA_ECOLI
Sequence: MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK
What is the function of this protein?
Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor.  In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex.  HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
What are the official names of this protein?
Bifunctional ligase/repressor BirA, Biotin operon repressor, Biotin--[acetyl-CoA-carboxylase] ligase, Biotin--protein ligase, Biotin-[acetyl-CoA carboxylase] synthetase.
What is the protein family that this protein belongs to?
Belongs to the biotin--protein ligase family.
Protein: TES1_ALTAL
Sequence: MEPEPLDPRAIGFMRRNLAMLRQTPMSVVLAGLILLASIYFPRFMFKSQMARFPLILEHLSSEQRRARFLVGAKALYKDGSQKFRGMAYRMQTLDEQQIVLPLSALTELRKAPEEVLSFYDMFSKVVDTIKRDLTPKLTKITSKICDEVDAALDTYLPSHGKWTEINVSKTALDIIAKVSAHLFIGGDVANDPGYLECTKNFTVHLGEATRAIKVTRVWLRPFLAPRLPEVKRLLETRTKLRSYVKRVIEEREAKIKNPDWVPPDDMMQWLLDRADRQKDTLEDCTAAQVLLILGTINASMQTLIAILHTLAVTPEYVEPLREEIRNTLNSDGSIPVSAMKEFGKMDSYFKEVGMHFPVIIEPYFRRVRKGFTLSNGQYLPPGVAIVIANPLVTDSKYDTFDGFRHYKLREASAQKDKPNHRWLIANETEFRWGYDNHVCPGRFYAHNLLKIIFARIVENYDIKMPGNVEGIEARYPMVEHGNVVMEPRDKPLLLRRVKSHQGHVD
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the phytotoxin tentoxin, an inhibitor the F1-ATPase activity of chloroplasts, resulting in chlorosis in sensitive plants (PubMed:27490569, PubMed:7881545).  Tentoxin is a cyclic tetrapeptide that consists of four amino acid residues: glycine (Gly), alanine (Ala), leucine (Leu), and dehydrophenylalanine (DPhe) (PubMed:27490569, PubMed:7881545).  In addition, both the Ala and DPhe residues are N-methylated (PubMed:27490569, PubMed:7881545).  The nonribosomal peptide synthetase TES assembles tentoxin from the four substrate amino acids (PubMed:27490569).  The adenylation domains of each of the 4 modules are responsible for the activation of Gly, Ala, Leu and DPhe, respectively (PubMed:27490569).  In addition, the N-methyltransferase domains in the second and fourth modules of TES could be responsible for N-methylation of Ala and DPhe residues (PubMed:27490569).  Finally, the condensation domain located in the termination module probably catalyzes the formation of the intramolecular macrocyclization and then the release of tentoxin (PubMed:27490569).  The cytochrome P450 monooxygenase TES1 is predicted to be involved in the formation of DPhe (PubMed:27490569).
What are the official names of this protein?
Cytochrome P450 monooxygenase TES1, Tentoxin synthesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YF19_SCHPO
Sequence: MSTKLVDHVEITVPTGKTYIQPVGLFINNQHVDSVHGGRVKVYSPSTEKLICEVADADEEDVDIAVKVARAAFQTDAPWRKFSSAQRGRCLSRLADCIEQNLEYLASIETLDNGKSITLARGDVQAAADCFRYYGGWADKDYGQTIETDIKRFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVACGNTIILKTAELTPLSALCLTKFVPECGFPPGVINVLSGDGRRCGNAISSHMDIDKVAFTGSTGVGRMVMRAAASSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCAGSRVYVQEDVYDEFIKRMVAKAKTLKVGDPFAEDTFQGAQVSKQQYERIVSYIESGIAHGAKLEIGGKRHGNLGYFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEAIRRGNNSTYGLAAGVHTNNITNAIKVSNALEAGTVWVNCYNLLHHQIPFGGYKESGIGRELGSYGLTNYTQTKAVHINLGMDSPI
What are the official names of this protein?
Putative aldehyde dehydrogenase-like protein C9E9.09c.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PYRG_CUPTR
Sequence: MTKFVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFVSAKMRKSNNFTTGQIYESVIRKERRGEYLGKTVQVIPHITNEIQAFIEKGAAASHDGKADVALVEIGGTVGDIESLPFLEAARQMSLRMGRNHCAFVHLTLVPFIASAGELKTKPTQHSVQKLREIGISPTALLCRADRPIPDDERAKISLFANIPQDAVISVWDADSIYKIPQMLNEQGLDRLICEELRLDPKPADLSMWQKLVNAQENPEHEITIGMVGKYVDLTESYKSLIEALRHAGMHTATRVNIEYIDSEELESGHLEVLAPLDAILVPGGFGKRGTEGKIRAIQYARENKIPYLGICLGMQLAVIEFARHLAGMADANSTEFNLETEHPVVALITEWVDREGKVEQRSADSDLGGTMRLGAQRVPVKEGTKARAIYGAEVNERHRHRYEVNNHYVPTLEKAGMVISARTPTENLPEMMELPESMHPWFVGVQFHPEFTSTPRDGHPLFKAYVEAALASQQRKGA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: EFG_THEAQ
Sequence: HYQEVPRQIQEKLIKGQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_HAEDU
Sequence: MELHIIFLILGGLLIVLLAGFSIYSARREKSRIFSNTFTTRQPATPIKNIVTDVPATLDPLQYGQNPVPTENESESETGHSVQIQQEVENSLREIKINLPVQETAEYTQTPLNTPIYHNQPAQPTFLQTAPPIEPLTIPTVEPIQPETTSVLEQSLEELERQAAERELDLYSDASVRIELAKNSIQTPIEEVAQPESTVITQNNIITLYVVAPEGQQFDGHYVVQSLEALGFQFGEYQIYHRHQHLGNNDTPVIFSVANMMQPGIFDLNNLDSYATVGLVLFMHLPSEGSDLVNLKLMLKAAESLAEALGGFILNEQRELFNETDRQAYFARVS
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: THBI_THETS
Sequence: ECENTECPRACPGEYEFDEDGCNTCVCKGCDDAQCRCSSDANGCESFCTCNTRCSAADECNPRCTCK
What is the function of this protein?
Potent thrombin-specific inhibitor.
What are the official names of this protein?
Theromin, Thrombin inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I15 (antistasin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSP_HAHCH
Sequence: MSDTRETLAELEQRDAFIGRHIGPDEAEKTAMLNALGVADMETLISKTVPETIRIKEGLELDGPCTEAQALAELKAFAERNKVFKTYIGMGYYNTLTPTVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQTMIGDLTGMEMANASLLDEGTAAAEAMTMCRRVNGKNKSNVFFVAEDCLPQTIEVVKGRAEPLGIEVVVGDPQKDLQNHDYFAVLLQYPGVNGDVRDYRELIKTAHESNALAIMAADILSLTLLTPPGELGADIAIGNSQRFGVPLFFGGPHAAYIATKDEYKRSLPGRLVGVSVDANGDKAYRLALQTREQHIRRQNATSNICTAQALLAITASMYGAYHGPEGLKRIARRVHRLTTILAEGLKQAGRSVNTAHFFDTVSVATGGDTDAVYQAALQQKINLRRIDDNTLGVSLDETTTREDVAALLHVFASGKPVADVATLDSSAKDAIPAELRRQSAFMTHTVFNRYHSETEMLRYLRRLSDKDLALDRTMIPLGSCTMKLNATTEMTPVSWDGFCAIHPFAPLDQTEGYRALIADLERMLSAATGYAAFSLQPNAGSQGEYAGLLAIRAYHHSRGEGDRDVCLIPNSAHGTNPASAQMVGMKVVAVKCDDNGNVDLNDLRLKAEQHSAKLAALMATYPSTHGVFEEGIREVCSIVHQHGGQVYIDGANLNAMVGLCKPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPIGVAAHLAPFLPGHSAMGETADKAIAPISAAPWGSAGILPISWTYIRMMGGEGLTEATKSAILNANYIAKRLEPHYPVLYTGSQGFVAHECIIDVRPFKDSCGVTVDDIAKRLIDFGFHAPTMSFPVPGTLMIEPTESESLAELDRFCDAMIAIREEIRAIENGEYDVDHSPLHHAPHTAADLVGDWDRPYSRERGVYPLKALKADKYWSPVGRIDNVYGDRNLVCACPPMTEYED
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: DPP4_ARTBC
Sequence: MKTSQFLSLLLLAGIAQAIVPPREPRPPTGGGNKLLTYKECVPRATISPRSTSLAWINSDEDGQYISQSDDGALILQNIVTNTNKTLVAADKVPKGYYDYWFKPDLSAVLWATNYTKQYRHSYFANYFILDIEKGSLTPLSQDQAGDIQYAQWSPMDNSIAYVRGNDLYIWNNGKTKRITENGGPDIFNGVPDWVYEEEIFGDRFALWFSPDGEYLAYLRFNETGVPTYTIPYYKNKQKIAPAYPRELEIRYPKVSAKNPTVQFHLLNIASSQETTIPVTAFPENDLVIGEVAWLSSGHDSVAYRAFNRVQDREKIVSVKVESKESKVIRERDGTDGWIDNLLSMSYIGDVNGKEYYVDISDASGWAHIYLYPVDGGKEIALTTGEWEVVAILKVDTKKKLIYFTSTKYHSTTRHVYSVSYDTKVMTPLVNDKEAAYYTASFSAKGGYYILSYQGPNVPYQELYSTKDSKKPLKTITSNDALLEKLKEYKLPKVSFFEIKLPSGETLNVKQRLPPNFNPHKKYPVLFTPYGGPGAQEVSQAWNSLDFKSYITSDPELEYVTWTVDNRGTGYKGRKFRSAVAKRLGFLEPQDQVFAAKELLKNRWADKDHIGIWGWSYGGFLTAKTLETDSGVFTFGISTAPVSDFRLYDSMYTERYMKTVELNADGYSETAVHKVDGFKNLKGHYLIQHGTGDDNVHFQNAAVLSNTLMNGGVTADKLTTQWFTDSDHGIRYDMDSTYQYKQLAKMVYDQKQRKPERPPMHQWSKRVLAALFGERAEE
What is the function of this protein?
Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.  Contributes to pathogenicity (By similarity).
What are the official names of this protein?
Probable dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DppIV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRF_CORGB
Sequence: MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSSISVPEPRMLLIKPYEMSSMQVIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGKGEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKELDKVTAGFVAQVDEVVARKEKELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_ACISJ
Sequence: MITVRTIPELRAAIAAHPGAGRPGKRPAFVPTMGNLHDGHIALVRQARPLGDVLVASIFVNRLQFLPHEDFDSYPRTWEADCAKLEAAGCDIVFAPRESDLYPEPQTFKLQPDPQLADILEGHFRPGFFTGVCTVVMKLFSAVFFASGGGTAVFGKKDYQQLMVIRRMVQQFALPVEVVAGETARADDGLALSSRNGYLSTAERVQAVQLSAALRALAQAAQAPGAPPLAALEQQALQTLAQQGWAPDYLTVRQRHDLQPPAAGAAAGTLVALGAARLGSTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_PERMH
Sequence: MGKYRKKAREIVFRTLYTYDIKGGDLFEIMEDHIKDIRGKLSKKTVDYIYSILKGIDEHLPEIDDILRENLKNWRLERLGYPERALLRLGVYELLFSDIEDKGRVFMDILDLTKCYIDNPDTVKFINGVLSTVYKNRQKVNQ
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MPGP_SALTI
Sequence: MLSIHDPLLIFTDLDGTLLNSHTFEWQPAAPWLTRLHESGVPVILCSSKTAAEMLQLQTTLNLQGLPLIAENGAVIQLDVHWEDHPNYPRLIAGISHNEIRLVLHKLREKEQFKFTTFDDVDDQVISEWTGLNRAQSALTRLHEASVSLIWRDSDERMAQFVARLNDLGLQFVHGARFWHVLDASAGKDQAANWLIEAYRRQWRARPLTLGLGDGPNDAPLLDVMDYAVVVKGLNREGVHLRNDDPQRVYRSQNEGPDGWREGMDYFFSRS
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG5_CRYNB
Sequence: MASPNPAQSTTILFRRLTWQSAVTISIRLADGEPGAGNACDRYYIKAPRYSYLPLFIPEIRENLVELALDDAQLEQIDEKNWWFEEEVSEEDKQRFVRQGACRWHWPIDLVDIHSFISRPQPLPSSIELSSTPRVISLLLHLSNPPQDRLLMPNSIEVCKSQWLNQVKEADFVRWRNTNRVTNLRRVDLEAGWDGIVNNDFDLYAQMVNKIVPLPLLTSSNSTQPSRPSSADPSGPPRAPDSSYATRAIPFKIYLPDNAPVIQEIVPPISESGKPTTLLAVLQVHLPLLFPISSENPYELAFPIAQGILIPQEAEVAWIASCLCGVDGWVRVGVCLSAA
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: ARGC_DESPS
Sequence: MIKIAIIGASGYTGVELSRLLCNHPQVEITAVTSRQYAGVALSEVFPNLRGRTSLICENLTIEELCLRADLFFAAVPHKTAMNIVPQLLAAGKKVIDLSADFRLNSAAVYEEWYQEHSAKEFLSQAVYGLPELYREQIAKTQLLANPGCYPTSIILGMAPLLRAGIIKPQSIIADSKSGTTGAGRGAKVGSLFCEVNDGFKAYGVGRKHRHTPEIEQELGKLANTDFNITFTPHLLPISRGILSTIYADLNCEIEADEVQALYEEMYKDEPFVRVLPLGSAPATQYVRGSNYCDIGFAIDQTTGRIIVMSAIDNVVKGAAGQAVQNMNIMCGFAEQEGLEIVPLFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3859_BRUME
Sequence: MRLRNFYSALALSAAVFAGPLYAAAPAMAAGTISGGFDVGPGGFQGNFNPLAATGGFTWLVTYFEPLVIYDDKLENIVGDLAKSFEISPDQLTYTFKLAHAKWHDGEPFTSKDAKFTFDLARNGKTGSVFAARLASIASVETPDEKTVVIKLKEPSPSMLDTLTKVMMLPEHALASIPPEQLAKNAWWSSTPIGTGPFKFNKYVADQYVELTANPDYRGGRPQVDKLINRYFADPAAAIAALRSGEIQFTYVDSNDVSTFSSDSAFRVIEGDSFVVNYVGFNQEVPLWKDLKVRQAFMHAINRDAIIQSLYGGAAKPANCVYVADRLVPKAIDAYAYDPQKARQLLDEAGWDKINGSKPITILTYYNSPLVANVLAAMQAMLAQVGINIVPRTVDTPTYNSIVYKQGGTADEFPLIFAGLQNGPDPSSINIGLNEKQIPPAGSNIMRIRMPAVTKALDAALAETNPAKRDARYQDVCKATNANLPWGTMWVANRYGVASSKLENFIWTPAPAGGPYQAHPEKWSILE
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.
What are the official names of this protein?
Putative ABC transporter peptide-binding protein BMEII0859.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRES_MYCTO
Sequence: MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWFKHAVFYEVLVRAFFDASADGSGDLRGLIDRLDYLQWLGIDCIWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFVALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPYGDYYVWSDTSERYTDARIIFVDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMIDVIRFWLGLGIDGFRLDAVPYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRVLLAEANQWPGDVVEYFGDPNTGGDECHMAFHFPLMPRIFMAVRRESRFPISEIIAQTPPIPDMAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPRMKANVGIRRRLAPLLDNDRNQIELFTALLLSLPGSPVLYYGDEIGMGDVIWLGDRDGVRIPMQWTPDRNAGFSTANPGRLYLPPSQDPVYGYQAVNVEAQRDTSTSLLNFTRTMLAVRRRHPAFAVGAFQELGGSNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQPIELDLQQWTNYTPVELTGHVEFPRIGQVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERRL
What is the function of this protein?
Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation.  Also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose.  TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P).  Might also function as a sensor and/or regulator of trehalose levels within the cell.  Thus, when trehalose levels in the cell become dangerously low, TreS could expedite the conversion of glycogen to maltose via its amylase activity and then convert the maltose to trehalose; but this enzyme also could expedite or promote the conversion of trehalose to glycogen when cytoplasmic trehalose levels become too high.
What are the official names of this protein?
Trehalose synthase/amylase TreS, Maltose alpha-D-glucosyltransferase, MTase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. TreS subfamily.