PharMolix/UniProtQA huggingface dataset:
Protein: BGLD_ASPFN
Sequence: MRFVSLAVGAALLGAAGASSISSNVGLLKANGVALGNWEAAYEKASAFVSGLTTDQKLALITGSNVESTNGNFTPLYFLDGDMGLQDFYYVSAFSLSSALAMTWDRDAIYEQAKAVGSEFYNKGVQVVAGPTSQPLGRTPWGGRGVEGFGPDPYLNGLATGLTTKGYVDAGVIPGGKHFLLYEQETNRTSSFGSSGEGSPYSSNADDKTIHETYLWPFYDAVKNGAGAVMCAMTKVNGTMACENSDLLMKMLKTELGFPGMVWPDMNGQNSAKGSALGGEDYGSSSIWSTSTMESFLSNGTLSEARLNDMAIRNLIGYYYVNLDNGRQPTRQTTDVYVDVRANHSKLIRENGAKSMALLKNEGVLPLSKPRVMSIFGAHAGPIMGGPNSNVDVMGSGPTYQGHLATGSGSGMASMPYLITPYGALTNKAAQDGTVLRWVLNDTYSSGGGSSLVPSSTSSTAVEPSFENFATGSDICLVFINALAGEGADRTELYNADQDAMVNTVADNCNNTVAVVNTVGPRLLDQWIEHDNVTAVLYGSLLGQESGNSIVDLLYGDVNPSGRLVHTIAKNESDYNVGLCYTAQCNFTEGVYLDYRYFDAHNITPRYPFGHGLSYTTFHYSSLAIKAPSSITKAPKGNLTVGGPSDLWDVVGTVSARIANNGTLSGAEVPQLYLGFPDSADQPVRQLRGFDRVELSAGQEAVVTFNLRRRDISYWNVKTQQWMVAGGKYTVFVGGSSRDLRLNGTFFLWVGS
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase D, Beta-D-glucoside glucohydrolase D, Cellobiase D, Gentiobiase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_BURP1
Sequence: MQLTELIETTVTGLGYELVDLERTGRGMVCVYIDQPAGITIDDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFTRFAGSEAVITLKKPLDGRKTYRGILHAPNGETIGLEFERKKGEAAMLDFTLADVDKARLIPHVDFRSRKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYB1_CROXC
Sequence: MGRKPCCSKEGMNRGAWASMEDKILVTYIKTHGEGKWRSLPKRAGLKRCGKSCRLRWLNYLRPGIKRGNISEDEEDLIIRLHNLLGNRWSLIAGRLPGRTDNEIKNYWNTNLGRRVHDQSHQHCRPNPTITSTKPADAPPANANTVATMPVRTKAARCTRAFFSDDLSDQKEVAANNDGLDNKKEEFDAVGSIGPLLQENVGNAVGEDTNIDMAVSLDSLLLFDSFQVDDGINLQSMAALLDSEDQWF
What is the function of this protein?
Transcription activator involved in the spatiotemporal regulation of flavonoid biosynthesis specifically in the corms of Montbretia (PubMed:31004005).  Activates the promoters of enzymes involved in the biosynthesis of the flavonol kaempferol and the flavonol-glycoside kaempferol-rhamnoside (PubMed:31004005).
What are the official names of this protein?
Transcription factor MYB1, Myb-related protein 1, CcMYB1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAAA_ECOLX
Sequence: MSGQVPEYQFWLLAEISPVHSEKVINALRDYLVMGYNRMEACGRHGVSPGYFSGALKRFQRVSQTVYRLVPFYFPEAGHEVHRGE
What is the function of this protein?
Regulates the transcription of genes involved in the biosynthesis of F1845 fimbrial adhesin.
What are the official names of this protein?
F1845 adhesin operon regulatory protein.
Protein: MRH4_ASPFU
Sequence: MNRLGRLPLPLPPSVCLFCRFRATASLPSSLQATRSMATARLRRRVARMTLSPDVAKPSVVKKTRGDKERFGPFAGMNQTEARIRETPRARSRAAQKRSGEPEEDSQKESPLYKALKMQTALTPIPYGRRAAIKAKIADITSFDQFQLLPVVRNSISSQALPGLVDVTPTPIQRLAIPRLLEEPKTEKKPTKADDDEPRYDQYLLAAETGSGKTLAYLLPVVDAVKREEARDKELEKKEQEEKAREREERLKNRAFDIEPEIPPLSNAGRPRAIILVPTSELVAQVGVKVKALSHTVKYRSGMISSNFTPRRIKNTLFHPDGIDILVATPHLLASIAKTEPYVLSRVSHLVLDEADSLLDRSFAPTTTEIISKAAPSLRKLILCSATIPRSLDNLLRKRYPDIKRLTTPNLHAIPRRVQLGVVDIEKDPYRGNRSLACADVIWSIGKAGDAESEGPYASYVAPKTKKILVFVNEREEADEVAQFLRSKGIDAQSLSRDSDARKQEEILAEFTEAPPPPSPDEILLAQKKRRYEDAIPFEMPEKANQGSSRRLANTKVLVTTDLASRGIDTLAVKTVILYHVPHTTIDFIHRLGRLGRMGKRGRGVVLVGKKDRKDVVKEVREGMFRGQALI
What is the function of this protein?
ATP-binding RNA helicase involved in mitochondrial RNA metabolism.  Required for maintenance of mitochondrial DNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase mrh4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. MRH4 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRF1B_ARATH
Sequence: MAEAVDEDSGVGRSLEESSNGQHSQAGEALSEWRSSGQVENGTPSTSPSYWDIDDDDDYGLKPSELYGQYTWKIPKFSEITKREHRSNVFEAGGYKWYILIYPQGCDVCNHLSLFLCVANYDKLLPGSFAILEAGWSQFAQFTISVLSQDLKKSKFSDTLHRFWKKEHDWGWKKFMELPKLKDGFIDESGCLTIEAKVQVIRERVDRPFRCLDCGYRRELVRVYFQNVEQICRRFVEEKRSKLGRLIEDKARWTSFGVFWLGMDQNSRRRMCREKVDVILKGVVKHFFVEKEVSSTLVMDSLYSGLKALEGQTKNMKARSRLLDAKQLPAPIVSVDKDMFVLVDDVLLLLERAALEPLPPKDEKGRQNRTKDGNDGEEVNKEADERDERRLTELGRRTVEIFILSHIFSTKIEVAHQEAIALKRQEELIREEEEAWLAETEQRAKRGAAEREKKSKKKQAKQKRNKNKGKDKRKEEKVSFATHAKDLEENQNQNQNDEEEKDSVTEKAQSSAEKPDTLGDVSDISDSVDGSADILQPDLEDRDSSSVLWDTDALEIHPPSSEGSSRGRGISISTPNGITEGKSHSTMDDSSSTCSNDSIRSGVTNGSYQGNSLNFRNQKSPNKGKNQQVKAMTDAHSLASETDDQPSTLGTDPKGQNYSSEASNVGESDWVVVSHIQEPEGSRNRIPVGRERKTVQSIVNSVDMDRPKEKSTAVLSSPRNVAKNPSPLTQTKPEKKSISTADGIPNRKVLATGPPSSSQVVLPSDIQSQTVGLRADMQKLSAPKQPPATTISRPSSAPIIPAMRPSPITVSSSVQTTTSLPRSVSSAGRLGPDPSLHNQQTYTPQSYKNAIVGNSLGSSSSSFNHHPSSHGVVPTTLPSSSYSQAPTSSYQSSFPYSQDGLLWTGRSPSSVNMGMYNNTYSPAVTSNRSLNHMDVQIAQQQAQSMMTDEFPHLDIINDLLEDEQCSNMVYNGSIFNPQPQVFNGQYSSYHGELLSGGRTRSFGEEGLHYMARGPYGTDGMMPRQWQMTNMDLSLPAMRSNGMEDGTSSAANYHHSYFGLDASNPSFTSGINGYTEFRPSNGH
What is the function of this protein?
Functions redundantly with TRAF1A in the regulation of plant immune response.  Contributes to the turnover of the nucleotide-binding domain and leucine-rich repeat-containing (NB-LRR) immune receptors SNC1 and RPS2.  May associate with an E3 ubiquitin-protein ligase complex, which modulates ubiquitination and subsequent degradation of NB-LRR immune sensors to maintain their homeostasis (PubMed:26867179).  Functions redundantly with TRAF1A in the regulation of autophagosome formation.  Required for SINAT1- and SINAT2-mediated ubiquitination and destabilization of ATG6.  Functions as molecular adapter that helps to regulate autophagy by modulating ATG6 stability (PubMed:28351989).
What are the official names of this protein?
TNF receptor-associated factor homolog 1b, Protein MUTANT SNC1-ENHANCING 13.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Predominantly expressed in the cytoplasm (PubMed:26867179, PubMed:28351989). Associates with starvation-induced autophagosomes in continuous darkness (PubMed:28351989).
Protein: ACEK_ECO55
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYGEMLF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_OENOB
Sequence: MPKMKTNRASAKRFKKTASGGFKAGQAFTSHRFHGKTKKQRRQLRGTAMMNKVNVKRYAKILSNL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: EFPL_SERP5
Sequence: MAKANEIKRGMAISYNGKLLLVRDIDVQSPSARGASTLYKMRFSDVRTGLKVEERFKGDDILDTISLSRRKVNFSYIDGEEYVFMDDEDYTPYIFKKDQIEDELLFIPEAGLPGMQVLTLEGQVLALELPQTVDMEIVDTAPGIKGASASARNKPATMATGLTIQVPEYLSAGDKIRIHIAERRYMSRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: NUOI_SALTI
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFELGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYR_LIGS1
Sequence: MDYKVKVAQVIEQAVDGKLSQEDILAKIEKPKTLNLGDYAFPAFVLSKVLRKAPQMIASELVEKIDQTGFEKVEAVGPYVNFFLDKKEFSKDILSEVLSEGSAYGNQDLGHGGNVPIDMSSPNIAKPMSMGHLRSTVIGNSLALLLEKVNYKPIKIDHLGDWGTQFGKLIVAYKLWGSEEEVKADPINNLLKYYVRFHEEDVNNPELDEEAREWFKKLEDGDEEALKLWKWFREESLKKFTEVYDRLNITFDSYNGEAFYNDKMDEITDLLQEKGLLKESQGAEIVDLEKYDLNPALIRKTDGATLYITRDLAAALYRYRTYDFVQSLYVVGQEQTNHFKQLKAVLKEMGYDWSDDIHHIPFGLITSGGKKLSTRSGRVILLEEVLDDAVKLANKQIEEKNPNLADKEEVAEAVGVGAVVFHDLKNERINSFDFNLDEVVRFEGETGPYVQYSHARAMSILRKAGDLELDSDNLEISDPEAWQTLRLLAAFPETVKKAVSEYEPSVVAKYAIHLAKAFNKYYAHSRILNDDAEKNARLALVQSVATTLKESLRLLGVKAPNEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_ALIF1
Sequence: MSRTVFCVRLNKEADGLDFQLYPGELGKRIFDNISKEAWGQWQHKQTMLINEKKLNMMDPEHRKLLETEMEGFLFDGKDVVIDGYTPPSE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: IFT74_HUMAN
Sequence: MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQNDRETQSLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELDTLQQQLDSQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPMEEREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYKELKKREEHMDTFIETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQISSITNQELKMMQDDLNFKSTEVQKSQSTAQNLTSDIQRLQLDLQKMELLESKMTEEQHSLKSKIKQMTTDLEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIMEKQNIEYEALKTQLQENETHSQLTNLERKWQHLEQNNFAMKEFIATKSQESDYQPIKKNVTKQIAEYNKTIVDALHSTSGN
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium (PubMed:23990561).  Binds beta-tubulin via its basic region (PubMed:23990561).  Required for ciliogenesis (PubMed:23990561).  Essential for flagellogenesis during spermatogenesis (PubMed:33689014).
What are the official names of this protein?
Intraflagellar transport protein 74 homolog, Capillary morphogenesis gene 1 protein, CMG-1, Coiled-coil domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the IFT74 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasmic vesicle. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Localizes along primary cilia at interphase and around the basal body/centriole at interphase and mitosis (PubMed:15024030). In male germ cells, strongly expressed in the vesicles of spermatocytes and round spermatids and also in the acrosome and centrosome regions of elongating spermatids and in developing sperm tails (By similarity).
Protein: Y418_SHEPC
Sequence: MTKKIEVAQIRVLFLGIWRFLQHLRLRLVEDQINIRAGHLAYVTLLSLVPLVAVTMSMLSAFPVFKGIRGQIEAFVYENFLPAAGDTVQIYINEFVGNASKGTAVGIAALVVVAIMLISAIDKSLNNIWRTKEKRSVVVAFSMYWMVITLGPVLVGASLVATSYVVSLKLFEDDTFSGVVPLFIERLPMLFSVAAFLLLYMVVPNQKVKFLHALLGALVAALLFELGKKAFALYVTQFPSYEAIYGALATIPILFVWVYLSWMIVLLGAEITAAMPEYLDYESSFDKDEASTKT
What are the official names of this protein?
UPF0761 membrane protein Sputcn32_0418.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURB_STRMU
Sequence: MMLNEMNKSLEGVDIRINEPLKKYTYTKVGGPADFLAFPRNRYELARIVKFANQNNLPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVTVDGYVIEAEAGSNLIETTKVAQYHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHILISAQVLTRDGEIKTIEARDMRFGYRHSVLQDNQEVVVSAKFSLKPGDYTIISQEMQRLNHLRALKQPLEHPSCGSVFKRPLGHFAGQLIMEAQLMGHRIGGVEVSTKHAGFMVNVANGSAKNYEDLIADVIHRVKENSGVTLEPEVRIIGEKEVQMEDS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSS_BUNYW
Sequence: MMSLLTPAVLLTQRSHTLTLSVSTPLGLVMTTYESSTLKDARLKLVSQKEVNGKLHLTLGAGRLLYIIRIFLATGTTQFLTMVLPSTASVDSLPGTYLRRC
What is the function of this protein?
Inhibits host transcriptional machinery, by producing modifications to the phosphorylation state of the C-terminal domain (CTD) of RNA polymerase II.  Inhibits phosphorylation at serine 2 in the heptapeptide repeat (YSPTSPS) of the CTD of RNA polymerase II, suggesting that the elongation step of transcription and/or 3'-end processing is prevented.  Inhibition of host transcription machinery leads to shut off of host cell protein synthesis and inhibition of the host innate immune response.  NSs also seems to be involved in the nuclear relocalization of host PABP1.
What are the official names of this protein?
Non-structural protein NS-S.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus NS-S protein family.
Protein: DXMT2_COFAR
Sequence: MELQEVLHMNGGEGDTSYAKNSSYNLFLIRVKPVLEQCIQELLRANLPNINKCFKVGDLGCASGPNTFSTVRDIVQSIDKVGQEKKNELERPTIQIFLNDLFQNDFNSVFKLLPSFYRNLEKENGRKIGSCLIGAMPGSFYSRLFPEESMHFLHSCYCLHWLSQVPSGLVTELGISANKGCIYSSKASGPPIKKAYLDQFTKDFTTFLRIHSEELISRGRMLLTFICKEDEFDHPNSMDLLEMSINDLVIEGHLEEEKLDSFNVPIYAPSTEEVKRIVEEEGSFEILYLETFYAPYDAGFSIDDDYQGRSHSPVSCDEHARAAHVASVVRSIYEPILASHFGEAILPDLSHRIAKNAAKVLRSGKGFYDSVIISLAKKPEKADM
What is the function of this protein?
Involved in the biosynthesis of caffeine.  Catalyzes the conversion of 7-methylxanthine (7mX) to theobromine and of theobromine to caffeine.  Has 1-N-methylation activity.
What are the official names of this protein?
3,7-dimethylxanthine N-methyltransferase 2, CaDXMT2, Caffeine synthase 1, Caffeine synthase 6, CtCS6.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: ANP4_ZOAAM
Sequence: QSVVATQLIPINTALTPAMMEGKVTNPIGIPFAEMSQIVGKQVNTPVAKGQTIMPNMVKTYAA
What is the function of this protein?
Contributes to protect fish blood from freezing at subzero sea water temperatures.  Lowers the blood freezing point.  Binds to nascent ice crystals and prevents further growth (By similarity).
What are the official names of this protein?
Ice-structuring protein SP1(HPLC 4), ISP SP1(HPLC 4), Antifreeze protein SP1(HPLC 4).
What is the protein family that this protein belongs to?
Belongs to the type-III AFP family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_METFK
Sequence: MSAIVDIIAREIIDSRGNPTVEVDVLLESGVIGRAAVPSGASTGTKEAVELRDGDAARYLGKGVLQAVENVNTEITEAIIGLDVEEQSFIDQTLIDLDGTENKSRLGANAILAVSMACARAAAEESGLPLYRYLGGSGFMQLPTPMMNIINGGAHAENSVDMQEFMIIPAGLPTFREALRAGAEVFHALKKILHSEGLATTVGDEGGFAPDLPSNEAAIQYILQAITAAGYEPGRDILLGLDCASSEFYKDGLYHLESEGLQLTSAQFADYLATWVDKYPIVSIEDGMSEHDWDGWKLLTDRIGKKVQLVGDDLFVTNAKILREGIQKGVGNSVLIKVNQIGTLTETFTTIETAKRAGYTAVISHRSGETEDTTIADISVATNALQIKTGSLSRSERIAKYNQLLRIEEELGDATSYAGKEAFYNLK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: A1KA4_LOXDE
Sequence: WIMGHMVNAIAQIDEFVNLGANSIETDVSFDDSANPEYTYHGVPCDCGRTCTKWEYFNEFLKGLRKATTPGDSKYHEKLVLVVFDLKTSSLYDNQASDAGKKLAKSLLQNYWNNGNNGGRAYIVLSIPNLAHYKLITGFKETLTSEGHPELMDKVGYGFSGNDEIGDVAKTYKKAGVTGHVWQSDGITNCLLRGLDRVRKAVANRDSSNGYINKVYYWIVDKRATTRDALDAGVDGIMTNYPDVIADVLNESAYKAKFRIASYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LdSicTox-alphaIB1aiv, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TTCA_SALPC
Sequence: MQEIQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPAYLEPLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIVRFAEAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVDGGDLAFDREEIPLQPAGWQPEEDDTSLEALRLDVIEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NORR_ECOL6
Sequence: MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGEAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYNFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEVAAVPVVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: DUOX1_CAEEL
Sequence: MRSKHVLYIAILFSSIFGGKGIQQNEEFQRYDGWYNNLANSEWGSAGSRLHRDARSYYSDGVYSVNNSLPSARELSDILFKGESGIPNTRGCTTLLAFFSQVVAYEIMQSNGVSCPLETLKIQVPLCDNVFDKECEGKTEIPFTRAKYDKATGNGLNSPREQINERTSWIDGSFIYGTTQPWVSSLRSFKQGRLAEGVPGYPPLNNPHIPLNNPAPPQVHRLMSPDRLFMLGDSRVNENPGLLSFGLILFRWHNYNANQIHREHPDWTDEQIFQAARRLVIASMQKIIAYDFVPGLLGEDVRLSNYTKYMPHVPPGISHAFGAAAFRFPHSIVPPAMLLRKRGNKCEFRTEVGGYPALRLCQNWWNAQDIVKEYSVDEIILGMASQIAERDDNIVVEDLRDYIFGPMHFSRLDVVASSIMRGRDNGVPPYNELRRTFGLAPKTWETMNEDFYKKHTAKVEKLKELYGGNILYLDAYVGGMLEGGENGPGELFKEIIKDQFTRIRDGDRFWFENKLNGLFTDEEVQMIHSITLRDIIKATTDIDETMLQKDVFFFKEGDPCPQPFQVNTTGLEPCVPFMQSTYWTDNDTTYVFTLIGLACVPLICYGIGRYLVNRRIAIGHNSACDSLTTDFANDDCGAKGDIYGVNALEWLQEEYIRQVRIEIENTTLAVKKPRGGILRKIRFETGQKIELFHSMPNPSAMHGPFVLLSQKNNHHLVIRLSSDRDLSKFLDQIRQAASGINAEVIIKDEENSILLSQAITKERRQDRLDLFFREAYAKAFNDSELQDSETSFDSSNDDILNETISREELASAMGMKANNEFVKRMFAMTAKHNEDSLSFNEFLTVLREFVNAPQKQKLQTLFKMCDLEGKNKVLRKDLAELVKSLNQTAGVHITESVQLRLFNEVLHYAGVSNDAKYLTYDDFNALFSDIPDKQPVGLPFNRKNYQPSIGETSSLNSFAVVDRSINSSAPLTLIHKVSAFLETYRQHVFIVFCFVAINLVLFFERFWHYRYMAENRDLRRVMGAGIAITRGAAGALSFCMALILLTVCRNIITLLRETVIAQYIPFDSAIAFHKIVALFAAFWATLHTVGHCVNFYHVGTQSQEGLACLFQEAFFGSNFLPSISYWFFSTITGLTGIALVAVMCIIYVFALPCFIKRAYHAFRLTHLLNIAFYALTLLHGLPKLLDSPKFGYYVVGPIVLFVIDRIIGLMQYYKKLEIVNAEILPSDIIYIEYRRPREFKYKSGQWVTVSSPSISCTFNESHAFSIASSPQDENMKLYIKAVGPWTWKLRSELIRSLNTGSPFPLIHMKGPYGDGNQEWMDYEVAIMVGAGIGVTPYASTLVDLVQRTSSDSFHRVRCRKVYFLWVCSTHKNYEWFVDVLKNVEDQARSGILETHIFVTQTFHKFDLRTTMLYICEKHFRATNSGISMFTGLHAKNHFGRPNFKAFFQFIQSEHKEQSKIGVFSCGPVNLNESIAEGCADANRQRDAPSFAHRFETF
What is the function of this protein?
Plays a role in cuticle biogenesis (PubMed:11514595, PubMed:19406744, PubMed:23028364, PubMed:25480962, PubMed:18460651).  In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix (PubMed:11514595, PubMed:19406744, PubMed:23028364).  May regulate the production of ROS by playing a role in modulating proline catabolism (PubMed:27974198).  Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens (PubMed:19406744).  Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity (PubMed:28085666).
What are the official names of this protein?
Dual oxidase 1, DUOX1, Blistered cuticle protein 3, NADPH thyroid oxidase 1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the peroxidase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.