PharMolix/UniProtQA huggingface dataset:
Protein: TOP6B_HALS3
Sequence: MTSFQSTLDDDEDGIAEELAASQREISVAEFFEKNKHMLGFDSGARGLVTAVKEAVDNALDATEEAGILPDIYVEISEGRDYYTLIVEDNGPGITNAQIPKIFGKLLYGSRFHAREQSRGQQGIGISAAVLYSQLTSGKPVRIESRTQDSETANVYELIIDTDTNEPEISAETEVSAAKSDLRGTHGTRIEMALDANMRARGQLHDYIKHTAVVNPHARIELQEPGGELKSERAEEASLPAETDEILPHPHGVELGTLIKMLAETDSHSVSGFLQSEFTRVGSKTATGIIDAFRDEHFGREMRWRPPADADLEATVADAVANKDATHTAVFARTVADAVRDADSIAPAELGALVADAAADAQDDTGTSFGETVQANVVAAVRDALTSDRVADVLGPVDEATTVQKDDATVRGLAERIAAKFESGGDTDRVTRDTLDEYVFRAAENTAEYADATIGETARENVADALWARMATVPDDPPNTSALADDRDAASDLLAAMASVNVMAPPTSCLSPIEADQLEAGLRTEFDADFYAAATRDADVHGGDPFIVEAGIAYGGDIDSEGGVQLMRFANRVPLVYQRGACATTDVLGDIGWRNYNLSQPGGSGLPQGPAVIMVHVASTNVPFTSESKDAIANVPEIEAEIELAVREAARELKSFLQKRQSMRKRQQKQDVIMDILPTMAEKVGELTGRGGVDVSDSLARIMNNVLVERARSDDGQTVTLRVENHGTGSVDVDVTDIVSAEPDGVGDDASVVAMDDEYFVKWTPAVAGDDAAELTYSVDADADCELSVSGVADARLTVSEADT
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: Y758_PASMU
Sequence: MGGFTNTSGGIMHFVNRYCVVFLSSLLLIGCQDSLTGALYDRGESPEIVRYHVEKDQIYFFGLTPDKKIAVLGEKYHYLLKEKKPNDQYLIEKIVKLPFKQHLYSQMAIINSSKQKPDEISTSLYLALDLRQLSQKQRQTASMLGFKNLSYKSGFYDMIKQYQPQIDLEKLNREKQIWYREIDLVGHRYLPKAGANYVVKNQYPFSEMVEIHTDIEHLPARQNANAGTLLLTPFAAIADVATGILAVPAYIGLQAVCLGQSDGFICK
What are the official names of this protein?
Uncharacterized protein PM0758.
Protein: GRC3_ASPFU
Sequence: MKRKAEKQQATAPVSAFAARKARQQQARLLEPEKTAQNEPAVEPPSKRARRSPEEGAARQAANENDRVQTRRSARTKAETLSSAELAEKQPQESAAAARAQTAERTPPPEKGDADTFDAAEEEEEEEKEEDILERENGVGVIAVEDDAEGYESPADDVPQVQNFPLSKTRLNKSNIVSSDERTLCVRIKEKMTLVLLGHYDLWVKRGVISLMGAKLHPSPRLYRVYAPSTHSLPVIKCVAGVDGESEIEVKSCNSGIYRLRHLSPLYQRIWNGKHTAADKLTLKKVSASTKRTFSVLYTSSDDSWNRHLRPLHLEKQWSSAIRSLSQRGGRLKVLICGPKASGKSTFSRYLLNHLLSPAPQTENNHRNTDGVAFLDLDPGQPEFCPMGQVYLAHLRSPFFGPPFTHPSLAESQDGSIIRSHHIGAISPKEDPDHYVLAAMDLMDRYRALLASYPQCPLIINYPGWIFGLGLEVATWLVKSLGLSDVVYMSEKGPAEVVEPLGHAAQEARVPLTTLPSQPTDFVSRSSAQLRSMQVQSYFHMSHPSEIHNPQWLDTTMSRTRPLVVDYAGPRQGIRGIMVMGSQISPNLLHEALDGALVGVVAVESPNAIMGQADAAGFSGSSHGDATQGAEDLSSAASDIDMNDVTDACHGDVAPTSSSSFESMIIRTPNEDLPYLFVGSGSCNPLDPKASNCLGLALVRSIDVPSRKLELITPIPASKLRDALEQGHGIVLVRGMLDNPSWAISEDYYAARAAERRHQELVAKARKETNTRDGQDAAVDADTQGMVSALLKDRIRRASNVPWMTVIEDNSRRHREAAQRKKSLWKLRKKAYPGSESETDW
What is the function of this protein?
Polynucleotide 5'-kinase involved in rRNA processing.
What are the official names of this protein?
Polynucleotide 5'-hydroxyl-kinase grc3.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. NOL9/GRC3 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YBFR_AZOVI
Sequence: MAPPRTSTS
What are the official names of this protein?
Uncharacterized protein in bfr 3'region.
Protein: COX41_MOUSE
Sequence: MLASRALSLIGKRAISTSVCLRAHGSVVKSEDYAFPTYADRRDYPLPDVAHVTMLSASQKALKEKEKADWSSLSRDEKVQLYRIQFNESFAEMNRGTNEWKTVVGMAMFFIGFTALVLIWEKSYVYGPIPHTFDRDWVAMQTKRMLDMKANPIQGFSAKWDYDKNEWKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: CAIE_SALPA
Sequence: MSYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLILEAGSNLQDGCIMHGYCDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFQGEARQLLVGSPARVLRQVTDQELHWKRLNTKEYQDLAIRCRTGLSETKPLTQVEENRPRLKGTTDVKPKSAQ
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: PUB22_ARATH
Sequence: MDQEIEIPSFFLCPISLDIMKDPVIVSTGITYDRESIEKWLFSGKKNSCPVTKQVITETDLTPNHTLRRLIQSWCTLNASYGIERIPTPKPPICKSEIEKLIKESSSSHLNQVKCLKRLRQIVSENTTNKRCLEAAEVPEFLANIVSNSVDTYNSPSSSLSSSNLNDMCQSNMLENRFDSSRSLMDEALSVLYHLDTSETALKSLLNNKKGTNLVKTLTKIMQRGIYESRAYAALLLKKLLEVADPMQIILLERELFGEVIQILHDQISHKATRSAMQILVITCPWGRNRHKAVEGGTISMIIELLMDDTFSSERRNSEMAMVVLDMLCQCAEGRAEFLNHGAAIAVVSKKILRVSQITSERAVRVLLSVGRFCATPSLLQEMLQLGVVAKLCLVLQVSCGNKTKEKAKELLKLHARVWRESPCVPRNLYDSYPA
What is the function of this protein?
E3 ubiquitin-protein ligase that negatively regulates water stress response.  May control in coordination with PUB23 a drought signaling pathway by ubiquitinating cytosolic RPN12a.  Acts as negative regulator of the immunity triggered by the pathogen-associated molecular patterns (PAMPs), in association with PUB23 and PUB24.  Regulates EXO70B2 ubiquitination and degradation via the 26S proteasome to attenuate PAMP-induced signaling (PubMed:23170036).
What are the official names of this protein?
E3 ubiquitin-protein ligase PUB22, Plant U-box protein 22, RING-type E3 ubiquitin transferase PUB22, U-box domain-containing protein 22.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECOT_SALTI
Sequence: MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKVELLIGQTLNVDCNQHRLGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQNAIAR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS6_MICLC
Sequence: MRAYELMVLIDPEVDERTVEPTLKKYLEVVTNAGGTVDNIDVWGRRKTAYEIQKKSEAIYVVVNFQSEPAATQELDRLLNLNETILRTKIIRPEEQKITAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SYI_KLEAE
Sequence: DLAAKLNALGEELRFVLLTSGANVADYAQAPADAWQSDLLKGLKVVLSKAEGEKCPRCWHYTSDVGKVAEHAEICGRCVSNVAGDGEQRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECC2_AEDAL
Sequence: MNFAKVFVLVAMAVLLLVGQSEAGGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKALGK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-C type 2, Cecropin-C2.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_TREPA
Sequence: MGIQLIVFLGNPGAEYEETRHNAAWLLLTYLFPSIVLPWRCGCRGSIARIEGFEGSSEEVWLLKPLTYMNRSGKSVGAACAFLQTDAKQLLVVHDELELPFGVVSLKQGGGLGGHNGLRSIKEVLGTADFWRLRIGIGRPPSESVNIAQYVLSAFYPAEMAAFPKLGRATRDLLCQLVVTDQAATVTLLSAWRKKRLLSLCE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BZIP9_ARATH
Sequence: MDNHTAKDIGMKRSASELALQEYLTTSPLDPCFDLMNRDYTCELRDSLLWSEGLFPAGPFRDAQSSICENLSADSPVSANKPEVRGGVRRTTSGSSHVNSDDEDAETEAGQSEMTNDPNDLKRIRRMNSNRESAKRSRRRKQEYLVDLETQVDSLKGDNSTLYKQLIDATQQFRSAGTNNRVLKSDVETLRVKVKLAEDLVARGSLTSSLNQLLQTHLSPPSHSISSLHYTGNTSPAITVHSDQSLFPGMTLSGQNSSPGLGNVSSEAVSCVSDIWP
What is the function of this protein?
Transcription factor.
What are the official names of this protein?
Basic leucine zipper 9, AtbZIP9, bZIP protein 9, Basic leucine zipper OPAQUE 2 homolog 2, Basic leucine zipper O2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAK_LACP7
Sequence: MGKIIGIDLGTTNSCVAVMEGGKPVVIANTEGSRTTPSVVAFTKTGERIVGEPAKRQAVTNADKTISSIKRHMGTDFRVSIDDKKFTPQEISAMVLQKLKADAEGYLGEKISEAVITVPAYFNDAQRQATKDAGKIAGLDVKRIINEPTAAALAYGLDNEHEQKIMVYDLGGGTFDVSIIEIGDGVIEVLATSGDNRLGGDDFDERVTRYFIDEFKKAEGVDLSTDKMALQRLREAAEKAKKELSSATTTNINLPFITATSEGPKHFDLNLTRAKFDELTHDLVERTAIPVQNALRDAGLAPSELGKVLLVGGSTRIPAVQDKVKQLTGHEPSKSLNPDECVAIGASVQGGKLAGDTGAGDILLLDVTPLSLSIETMGGIATRLIERNTTIPSKKSQIFSTAADNQTAVDINVVQGERQFAKDNKSLGQFRLDGIPPARRGIPQIEVTFDIDANGIVNVSAKDLGTGKEQHITITAGSNMSDSDIDKAVREAAEYEAQDKKRKDAVDTRNDADSIVFQTEKALSEVGDKVSADEKTAVEADLNHLKDLVAKANPEVMSEGEVEDMKAAKEKLMNSAQALFAKLYESAQGAAGAGPDMSGAGPQGDTYAGDDVVDGDYREV
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: TPS11_RICCO
Sequence: MSMIGTKSFFISSSPKVPVGISWGPSSYRTNSSLSVRSPTLTCSISTISQPTRKEPATTKPEIMEELHEGTRKELLTSSSPIATMKLIDSIQRLGVGYYFEEEINTLLDRFLDLETTEDLLATALRFRLLRDNCFPAHSDVFGKFMNKDGKFKESLRKDVWGLLSLYEASYLGTKDEVELVEAMEFTKTCLEEQSIPLMAHKLSRHVSQALDLPRHLRMPRLEARNYIHEYSLESNNSPPLLELAKLEFNAVQSLHQKELIEIVRWWKQLGLVDKLGFARDRPLECYLWTVGIFPEPYNSTCRIELTKTIAILLVIDDIFDTYGSLPDLILFTEAVRRWDLNAMESLPEYMKICYMALYNTTNDIGFMILKRHGLSIVPHLKRTWIDMFEAFLTEAKWFNSGYVPTLEEYLDNGVTTGGTYMALVHSFFLMGQGVNKETVTMMEPYPDLFSLSGRILRLWDDLGTAREEQERGDVACSIECLMREKRISCDDEGRKQVRQLIRSLWTELNGELIAPSAMPLSIINASLNLARTAQVVYQHGDDKKGSSVDNQVQALIYIPISFPKRRDLKLL
What is the function of this protein?
Probable sesquiterpene synthase.
What are the official names of this protein?
Probable terpene synthase 11, RcSeTPS11.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: CH10_BURCE
Sequence: MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAIGPGKRDDKGAPIALDVKVGDRVLFGKYAGQTVKVDGQELLVMREEDIMAVVNAK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUB52_ARATH
Sequence: MEEKKVVRALSEHLSLPPPPSPSVAVAINGKKKSKYVVFWALEKFIPEGFTDFKLLYVRPPVSYIPTPMGIAVAVSELREDVVSAYKQELDWSANEMLRPYKKMFERRKVQVEVLLLDSLEPAAAIAEEIAGTGVTKLVIGMSLRGFFSRKIDMSSLIATAVPRFCTVYVISKGKLASVRPSESDASGSIRFERSSSTSGSTDSPRLPPEYQDFLSAVSEAQSRVSPFSPALKHSMGSNAVAQMDTSSSGTDQEEVSTGRGMEIVHSGIEGKKNKDESFSASFPMGTEAYNSMSWTSKWRDHEDRREMRSSSSSNNHDLVNMDWGAVVPENYSWVSHTASHMSDGLLSVHSITDNQVNLNFEIEKLRAELKHVQEMYAMAQTETVGASKKLTELNQRRFEESEKLVELKEKEEVAKDTASKEKQRYEEAMKEAEKVKELMMKEALHRREAEFKAERDAREKDKLQASLVSPGVQYQHYTWEEIAAATSDFAENLKIGIGAYGSVYKCNLHHTTGAVKVLHAGETQLSKQFDQELEILSKIRHPHLVLLLGACPERGCLVYEYMDNGSLDDRLMLVNDTPPIPWFERFRIALEVASALVFLHKSKPRPIIHRDLKPGNILLDHNFVSKLGDVGLSTMVNQDDVSSRTIFKQTSPVGTLCYIDPEYQRTGIISPKSDVYSLGVVILQLITAKPAIAITHMVEEAIGDDAEFMAILDKKAGSWPISDTRELAALGLCCTEMRRRDRPDLKDQIIPALERLRKVADKAQNLLSRTPSGPPSHFICPLLKGVMNEPCVAADGYTYDREAIEEWLRQKDTSPVTNLPLPNKNLIANYTLYSAIMEWKSNKR
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
U-box domain-containing protein 52, Plant U-box protein 52.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RS3A_THESM
Sequence: MAKVNPRKRAAAAKDKWKLKDWYIVYAPEFFGNVEIGLTPADEPEKVKGRIIETTLRDVTGDFTKGHVKLYFRIHDVKGQNAYTKFKGHKLARSYIRSLVRRRTTRIDGIFNVTTKDGYKLRVMGMVIAIRRIQSSQERAVREVMEDLIRKKAEELTFTEFVLEAVNGKMGAELAREAKKIYPLKRAEIRKIKVLAEPEA
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: CHKA_MOUSE
Sequence: MKTKFCTGGEAEPSPLGLLLSCGGNAAPTPGVGQQRDAAGELESKQLGGRTQPLALPPPPPPPLPLPPPPSPPLADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRGGLSNMLFQCSLPDSIASVGDEPRKVLLRLYGAILKMRSCNKEGSEQAQNENEFQGAEAMVLESVMFAILAERSLGPKLFGIFPQGRLEQFIPSRRLDTEELRLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLNQVLRLKFSREARVQQLHKILSYNLPLELENLRSLLQYTRSPVVFCHNDCQEGNILLLEGQENSERRKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYTYEKYPFFRANIQKYPSRKQQLHFISSYLTTFQNDFESLSSEEQFATKEDMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMEYAQARFEAYFDQKRKLGV
What is the function of this protein?
This isoform plays a key role in lipolysis of lipid droplets following glucose deprivation (By similarity).  In response to glucose deprivation, phosphorylated by AMPK, promoting localization to lipid droplets (By similarity).  Phosphorylation is followed by acetylation by KAT5, leading to dissociation of the homodimer into a monomer (By similarity).  Monomeric CHKA isoform 1 is converted into a tyrosine-protein kinase, which phosphorylates lipid droplet structural proteins PLIN2 and PLIN3, leading to lipolysis of lipid droplets (By similarity).
What are the official names of this protein?
Choline kinase alpha, CK, CHETK-alpha, Ethanolamine kinase, EK.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Isoform 1]: Lipid droplet. Note=Isoform 1 localizes to lipid droplets following phosphorylation by AMPK.
Protein: SYA_XYLFM
Sequence: MNIPTKFTTSKIRSDFLEFFKNKGHKIVPSAPLVPGNDPTLLFTNSGMVQFKDVFLGAEKRSEVRVADVQCCLRAGGKHNDLDSVGYTARHHTFFEMLGNWSFGDYFKKEAITWAWELLTHVWELPPERLLVTVYRTDDESYALWRDMVGVPEDRIVRIGDNKGAPFASDNFWQMADTGPCGPCTEIFYDHGEHIPGGPPGSPGEDGDRFIEIWNLVFMQFDRQSDGTLVPLPTPCVDTGMGLERLAAILQHVHTNYEIDLFQTLILKAAELTAVADVQNKSLCVIADHSRACAFLIVDGVLPSNEGRGYVLRRIIRRALRHGWMLGVRQPFFNNMVPTLVAVMGDAYPKLQAAAESVMRTLLAEEERFAETLDVGMKIFNEVAAKVANGVIPGSDAFRLYDTYGFPVDLTADIARERGMRVDMAGFEAAMTQQRKTARAAGKFGRGVQLSAERAAMLSPTVFLGYEQLQADGLRVVALLSDGGLTDSASVGDEVIVLTDRTPFYAESGGQVGDIGTLMASDGVRLEVTDTQKLMGQFHGHVTRIVQGGVKVGDVLSGSVAVARRKMVALNHSATHLLHCALRSVFGTHVAQKGSLVAPDRLRFDFSHFEPISAAQMTLIERMVNDEVRANHLVMIEQMGMQAALDAGAMALFGEKYGEHVRVVKMGTSVELCGGTHITRTGDIGLFKIISECGVSSGVRRIEAVTGESALNHVLAEEHRLYEVAGLIGSNANDVVNHIRQLTDRQKTLERELEKLKGKLISGTITDLLSTAVNVADVKVVAARLDGLDGKALREALDRLKLQLSDAVIVLAGVTGGKVALVTAVNGPRAMGKVKADTLLSHVATQINGRGGGRVDFAQGGGEDGPSLRSALDGVATWVKQHLD
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_METKA
Sequence: METFVLAHNYQRPDVQLMADSVGDSLELALEAREIDADRIVMCGVDFMAEVVKALNPDREVVVPDHRAACGMAMRLRAKELREFRREHPDAAVVVYVNTSAEVKAEADVMCTSANAVEVVSSLPEDKIIFVPDGNLAAWVQKHVPDKEVIPFPEHGCCPVHHSLSPSDLRELCSQHPDAAVVVHPECPLEVCAMADFVGSTSQIRQYCEKEDASKIVMGTEEGLAFRIRRETGTEVIVPGHMVCPDMKINTGEKVERVLEARHVPEPLRVELDPDLISQVEEVVEEMFRLTR
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_ALTMD
Sequence: MSNQLASLRDITTVVADTGDIDAIKKYQPVDATTNPSLLLKAAGLPQYASLIDDAVAWAKLQSNDAEQQLTDASDKLAVAIGKEISGTIPGRISTEVDARLSFDTAATIEKAERLVQLYEDAGIDKSRILIKIASTWEGIQAAEALEKKGIQCNLTLLFSFAQAQACAEAGVYLISPFVGRILDWYKKATGTESYAPDEDPGVVSVTKIYNYYKEHGYKTVVMGASFRNIGEIQALAGCDRLTISPALLEELANEPGDLEVKLKDNDATKTPGERLTESEFRWAMNEDAMATEKLSEGIRNFAADQEKLEATLREKLSA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_XYLFT
Sequence: MVLERTLSIIKPDAVAKNVIGDIYSRFEKAGLKIVAAKYKQLSRREAEGFYAVHRDRPFFNALVEFMISGPVMIQVLESENAVARHRELLGATNPKDAAPGTIRADFAESIEANAAHGSDSVENAAIEVAYFFAATEIILR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK3_ARATH
Sequence: METFLFTSESVNEGHPDKLCDQISDAILDACLEQDPESKVACETCTKTNMVMVFGEITTAAKVDYEKIVRSTCREIGFISADVGLDADKCNVLVNIEQQSPDIAQGVHGHLTKKPEDIGAGDQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNKTCPWLRPDGKTQVTVEYKNDGGAMIPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPAKYLDDNTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVAAGLARRCIVQVSYAIGVPEPLSVFVDTYKTGTIPDKDILVLIKEAFDFRPGMMAINLDLKRGGNFRFQKTAAYGHFGRDDPDFTWEVVKPLKPKA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate (PubMed:12087191, PubMed:16365035).  Involved in the biosynthesis of lignin (PubMed:11844113).
What are the official names of this protein?
S-adenosylmethionine synthase 3, AdoMet synthase 3, Methionine adenosyltransferase 3, MAT 3.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_XYLFA
Sequence: MMNRVMHYFKSLLLLELLAGLWLTLKYTFRPKYTVLYPMEKFPQSPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITIDSAKREDGTRRTTRYDIDLFKCIFCGFCEESCPVDSIVETHILEYHFEKRGENIVTKPQLLAIGDRFEAEIAERRAADAAFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YH50_YEAST
Sequence: MKRDLIGPVKALIKINNCSCLSRCQISRLPHFFTFHPHFSTLIYYYNLKNCITSET
What are the official names of this protein?
Putative uncharacterized protein YHR050W-A.
Protein: MINY4_PONAB
Sequence: MDSLFVEEVAASLVREFLSRKGLKKTCVTMDQERPRSDLSINNRNDLRKVLHLEFLYKENKAKENPLKTSLELITRYFLDHFGNTANNFTQDTPIPALSVPKKNNKVPSRCSETTLVNIYDLSDEDAGWRTSLSETSKARHDNLDGDVLGNFVSSKRPPHKSKPMQTVPGETPMLASAWEKMDKLHLEPSLDVKRMGENSRPKSGLIVRGMMSGPIASSPQDSFHRRSLRRSLPSSSSTQPQEESRKVPELFIRTQQDILASSNSSPSRTSLGQLSELTVEKEKTTASSPPHLPSKRLPPRDRARRRDPSEDTLAVDSSTDADRMPLKLYLPGGNSRMTQERLERAFKRQGSQPVPVRKNQLLLSDKADGELGTLRLEDVEDELIREEVILSPVPSVLKLQTASKPIDLSVAKEIKTLLFGSSFCCFNEEWKLQSFSFSNTASLKYGIVQNKGGPCGVLAAVQGCVLQKLLFEGDSKADCARGLQPSDAHRTRCLVLALADIVWRAGGRERAVVALASRTQQFSPTGKYKADGVLETLTLHSLTCYGDLVTFLQQSIHQFEVGPHGCILLTLSAILSRSTELIRQDFDVPTSHLIGAHGYCTQELVNLLLTGKAVSNVFNDVVELDSGDGNITLLRGIAARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPGLLRDWRTERLFDLYYYDGLANQQEQIRLTIDTTQTISEDTDNDLVPPLELCIRTKWKGASVNWNGSDPIL
What is the function of this protein?
Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4, Probable deubiquitinating enzyme MINDY-4.
What is the protein family that this protein belongs to?
Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
Protein: THYX_THENN
Sequence: MKIPVLDKGFVELVDVMGNDLSAVRAARVSFNMELKDEEKDRRLVEYLMRHGHESPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGRYSKLTYEFYIPPLQRFGQTRIVPEKVIEKISHVVNESYQTYMELLEAGVPREVARIVLPLNLYTRFYWTVNARSLMNFLNLRADSHAQWEIQQYAVAIAKIFREKCPWTYEAFIKYAYKGDLLREV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.