PharMolix/UniProtQA huggingface dataset:
Protein: RL9_PECAS
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNVEFFEARRAELEAKLADVLTAAEARATKIKELGSVTIASKAGDEGKLFGSIGTRDIADAVTAAGVDIAKSEVRLPNGVLRTIGEHVVSFQVHSDVFAELNVVVVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SPEM1_BOVIN
Sequence: MAMAERPRPGWASYHNPNTNSCQDLGNSILLLLGLIICINIGINMVTLLWRRLRGFLHQVFRVICEKEASKLRSPGKQTQPSKHSSPAVHLRCTMDAVKMTVTPPPTRRRHRRGSSSRRARRPVAWAPDTDDDDDEKPPHQHTAACSHNWDYPEDWEGLQTAQRFWTPWAQDTLEPPTQTIRFQQTIEGRPLKREMQSDLGLEAYVYPVNPPLPSPQILSHKNSGGGAGAGAQAEQEQCAPAEPPILGPANVPDIPRRRSSGRVTYDARDVRRRLRELTREVEALSHCYPLASGSSTAEGTRKDWVYRSMTER
What is the function of this protein?
Required for proper cytoplasm removal during spermatogenesis.
What are the official names of this protein?
Spermatid maturation protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Cytoplasm.
Protein: SBCC_STAAR
Sequence: MKPLHLKLNNFGPFLKEEIDFSKIDNNELFLISGKTGSGKTMIFDAMTYALFGKASTEQREENDLRSHFADGKQPMSVTFEFQLNNRIYKVHRQGPYIKEGNTTKTNAKFDVFEMVDGKYEIRESKVISGTQFIIELLGVNADQFRQLFILPQGEFKRFLISNSREKQGILRTLFDSEKFEAIREILKEEVKKENAQIENRYQQIDLLWQEIESFDDDKIKGLLEVATQQIDKVIENIPLLQARSKEILAFVNESKETAIKDYEIIEKKTLENNILKDNINQLNKNKIDFVQLKEQQPEIEEIEAKLKLLQDITNLLNYIENREKIETKIANSKKDISETNNKILNLECDKRNIDKEKRMLEENGDLIESKISFIDKTRVLFNDINKYQQSYLNIERLRTEGEQLADELNNLIEGLEKVEDSIGNNESDYEKIIELNNAITNINNEINVIKENEKAKAELDKLLGSKQELENQINEETSTLKNLEIKLDRYDKSKLDLNDKESFISEIKSAVKIGDQCPICGNEIQDLGHHIDFDSIAKRQNEIKEIEANIHTMKSNIAVHNSEIKFVNEKISNINIKTQSDFSLEVLNKRLLENENALNNQRELNKFIEQMKEEKDNLTLQIHNKQLRLNKNESELKLCRNLITEFETLSKYNNITNFEVDYKKYVQDVNQHQEHSNQIEDKLIQLSQRKLIEQNNLNHYEKQLETYNNDLELNEQSIEMEMSRLNLTDNNDINEIIAWRGEQEELEQKRDTYKKRYHEFEMEIARLESLTKDKELLDSDKLKDEYELKKGKMNTLIDEYSAVHYQCQNNINKTQSIVSHINYLNQELKDQQEIFQLAEIVSGKNNKNLTLENFVLIYYLDQIIAQANLRLATMSDNRYQLIRREAVSHGLSGLEIDVFDLHSNKSRHISSLSGGETFQSSLALALGLSEIVQQQSGGISLESIFIDEGFGTLDQETLETALDTLLNLKSTGRMVGIISHVSELKNRIPLVLEVKSDQYQSSTRFKRN
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: MFSD5_MOUSE
Sequence: MLVTAYLSFVGLLASCLGLELSRCRARPPGRACSNPSFLQFQLDFYQVYFLALAADWLQAPYLYKLYQHYHFLEGQIAILYVCGLASTVLFGLVASSLVDWLGRKKSCVLFSLTYSLCCITKLSQDYFVLLVGRALGGLSTALLFSAFEAWYIHEHVERHDFPAEWIPATFARAAFWNHVLAVAAGVAAEAVASWIGLGPVAPFVAAIPLLALTGALALRNWGENYDRQRAFSKTCAGGLRCLLSDRRVLLLGVIQALFESVIFIFVFLWTPVLDPHGAPLGIVFSSFMAASLLGSSLYRIATSKRYHLQPMHLLSLAVLIVVFSLFMLTFSTSPGQENPVESFIAFLLIELACGLYFPSMSFLRRKVIPETEQAGVLNWFRVPLHLLACLGLLVLHDSDRKTGTRNMFSICSAVMVTTLLAVAGLFTVVRHDAELRVPSPTGEPYAPEL
What is the function of this protein?
Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
What are the official names of this protein?
Molybdate-anion transporter, Major facilitator superfamily domain-containing protein 5, Molybdate transporter 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCP3_COPCM
Sequence: GLTDQKSAPPGL
What is the function of this protein?
Serine protease.
What are the official names of this protein?
Alkaline protease Cc3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: RT10_DEBHA
Sequence: MLSRILGVRNHSFRAFSTIGVCYNKSNTSPKKYLSPNEFASQKQVDEIEEQAYKQNLLNEEYKYDPKYLSENELNPISKRPIPLNVELLKYKPVQLPPTHGHEVAKIEFKGYDKDDLIRASEFAARAAFYLGIPCSKVQSLKTEKRLYTVIKSPFAQAKSKENFKRTTYGRKVYAYDATPEVVDLWLSFINKHAIEGVKYNALIHTRESLDFCEKLDALSADDMHMPDAYKGSDDPIANKVEELLKSDTFKKYFDEANIAESPKESK
What is the function of this protein?
Involved in mitochondrial genome encoded proteins translation.  Involved in the binding of tRNA to the ribosomes (By similarity).
What are the official names of this protein?
37S ribosomal protein S10, mitochondrial, Mitochondrial ribosomal small subunit protein 10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PTH_CUPPJ
Sequence: MIKLIVGLGNPGAEYEATRHNAGFWLVDQLARMGGTTLRVEGRFHGLAGRARLWDQDIWLLKPSTFMNRSGLAVVSLARFYKILPDEIVVAHDEMDLPPGAAKLKRGGGAGGHNGLKDIAAHLTTQEFWRLRLGVGHPRNLPGGAGAGREDVVNFVLKPPRKEEQQAIDEAIDRSIDPLGLLARGDAERAMAQLHTVAR
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_SALEP
Sequence: MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RL23_BORGP
Sequence: MKAYDIIVSPMLTEKTNTQRESINVYVFKVNKRANKKEVGAAIKELFNVTPVSCNLLNIKSKAKVVVSRRGYPIGKGKTSSWKKAYVYLKKEDKIDIF
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y5261_AGRFC
Sequence: MEDIMTSLLVATSRVVVTISLAYVPVKSAFAAPQNAAGLCSAIAASSIPASRISLPTTGAKIQSATLIGGSDPANQNGEYCKVIGQIKPVDPKAPDIIWQVNLPSVWNGKMLQYGGGGYNGSIPPTTDKTTLGLDVVPTPLTQGYVTFGSDSGHQAPNADDASFAKNDEAMLNYGYMHIKKVLDVAKVLVTERYEKPVTRVYFQGGSTGGREGLTAASRWPESYDGILTNYPTANFVGLRLWGAGLARAVYDDKSAGWIPPKLVERISKEALKSCDGLDGVEDGLVGNMQQCRAQSAVLVQSLACKSDVTGNPDDCLTQAQIERTLKIYHEGYSLPYQLANGINTYPGYNSLEGIMMQLGSEPQMRTPPVSGPNAHHSSRSFEFLQNFVQRDQPLNLLSFDIREPGKLKDRIVELSDVIGATRTDWSTFSDRGGKIIWLQGNDDPSVSPLGNAKLFESIVAKMGADKVKGFMRFFLVPGLAHGGGRFSPTWDNLAALDNWVEHDVPPSNPVVVDATKSSTKGRSRPLCEYPSWPKYKGDGDVAIASSFSCADD
What are the official names of this protein?
Uncharacterized esterase Atu5261.
What is the protein family that this protein belongs to?
Belongs to the tannase family.
Protein: PRO_SRV2
Sequence: MGQELSQHELYVEQLKKALKTRGVKVKGNDLLKFFDFVKDTCPWFPQEGTIDIKRWRRVGDCFQDYYNTFGPEKIPVTAFSYWNLIKDLIDKKEADPQVMAAVTQTEKILKVSSQTDLRDNSHNKDMDLISLESDDEEAKAPSEKMTMSNKSPKKYPAMLASQNNNTDKDPDLSEVDWDGLEDEAAKYHNPDWPPFLSRPPPYNRTAATAPAVMAVVNPKEELKEKISQLEEQIKLEELHQSLIIRLQKLKTGNERVTSSGNIESHSRTPKWPGQCLPKGKYLINKNTEEYPPKDIFPVTETMDGQGQAWRHHNGFDFTVIKELKTAVSQYGATAPYTLAIVESIADNWLTPTDWNTLVRAVLSGGDHLIWKSEFFENCRDTAKRNQQAGNGWDFDMLTGSGNYANTDAQMQYDPGLFAQIQAAATNAWRKLPVKGDPGASLTGVKQGPDEPFADFVHRLITTAGRIFGNAEAGVDYVKQLAYENANPACQAAIRPYRKKTDLTGYIRLCSDIGPSYQQGLAMAAAFSGQTVKDLLNNKNKDRGGCFKCGKKGHFAKDCRDHSNKNPESKVPGLCPRCKRGKHWANECKSKTDSQGNPLPPHQGNRDEGPAPGPEASLWGSQLCSSQQQQSISKLNRASPGSAGLDLCSTTHTVLTPEMGPQTLATGVYGPLPPNTFGLILGRGSTTVKGLQIYPGVIDNDYTGEFKIMARAISSIITIPQGERIAQLVLLPLLRTAHKIQHPYRGDKNFGSSDIFWVQPITHQKPSLVLWLDGKAFTGLIDTGADVTIIKQEDWPSHWPTTETLTNLRGIGQSNNPRQSSKYLTWKDKENNSGLIKPFVIPNLPVNLWGRDLLSQMKIMMCSPNDIVTAQMLAQGYSPGKGLGKREDGILQPIPNSGQLDRKGFGNF
What is the function of this protein?
Enhances the activity of the reverse transcriptase.  May be part of the mature RT.
What are the official names of this protein?
Gag-Pro polyprotein.
What are the subcellular locations of this protein?
[Matrix protein p10]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein-dUTPase]: Virion. SUBCELLULAR LOCATION: [Protease 13 kDa]: Virion. SUBCELLULAR LOCATION: [Protease 17 kDa]: Virion.
Protein: AC4CH_ECOLU
Sequence: MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRFEDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTELKKVIADIYPGQTQFYVIEFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: ATP6_HAEIN
Sequence: MSGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFHGPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVKEYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITLQAFIFMMLTVVYLSIAYNKADH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KISS1_RAT
Sequence: MISLASWQLLLLLCVASFGEPLAKMAPVVNPEPTGQQSGPQELVNAWQKGPRYAESKPGAAGLRARRTSPCPPVENPTGHQRPPCATRSRLIPAPRGSVLVQREKDMSAYNWNSFGLRYGRRQVARAARG
What is the function of this protein?
Metastasis suppressor protein.  May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization.  Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54.  The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty.  The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.  Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals.
What are the official names of this protein?
Metastasis-suppressor KiSS-1, Kisspeptin-1.
What is the protein family that this protein belongs to?
Belongs to the KISS1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3891_BRUSU
Sequence: MDDKVETGNIDVRLLELLVCPLTKGPLEYDAERSELVSRKARLAYPVRGGIPIMLPSEARSLTE
What are the official names of this protein?
UPF0434 protein BRA0891/BS1330_II0884.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: MED15_KLULA
Sequence: MDDWRSTISTQERSQFVTELAQILADMSRINGGEKANFNLEKLKKSAEQFESSLYASCNSKDLYLDAMRKRIAAMDSAKRKSIEAQRQKLAQAQAQAQAVQRQQQQQQQQHHMQQQGSGQQQANGIPANINAQMFLNQQAQARQQAQRQIRSTLTGQQQQQPMPQQPQPQQQQPNMMRPQLTLQQQQQLANELKVTEIPRELLQKIPNLPPGITTWPQITFWAQKNRPSQNDLIITKKVYQLHQQLLNKSKLQQSNVNRMNTSVQQPGMGVQQSPNQRMNMNQVPQQQQQVRQQQQQQQQQQQQQHKQQPQHQEPPAVLGRLNQVFTQAEQKMLYEAGKKMIENLQRSGKLPPNLDSQQQLLYIKKYMNQMVLKKMQQLGIPIPMPGSAQQQSQLLQQQQQQQQQQQQQQRQQQIPQVQQAPLQQPQVQPPQSQQAQSRRQAMGMKPTPVIPNAGVMKPQPQQTPQNIQQPMMQQQSSPPPQQQQQQQQQSKISVPRPTEQDMLALKKLNAEVTKNPVKLNDITNRLTNDQKQQIRSKLHANQQLFSSVESFIPTLYMLTRNEEHIRQLLQIRMLTREIMEKAVRGVFLVEPNVVDKVIFRYQKYYEYTKEQLLRRQQQLMTMRQMQNNNPNLTANDLLNQQQLLQNRKLNLAMQSQTQEPPQIAAQQQQPQQPISGVNNNSNMGIVLDSSLNATSRSGTNTMEFLNSPEFSAISPAVPSPNKDKKNPATRAVKGKKNSQSGIPTSNPQSNSNASVVNSRTATPTVIPGSSPMFNNKSLASGQQNSPSPKTMINSPPQQDNPYKNDELALKKMAIRTAELMSRYKHRKEVFVMSSIDLFLSTFADCLDIKDDAVDLVHKTPQPILDQINGTGKKKLSKAAQKARDQDPVEISVRNNKLLMPSKSEKTLRSFKIPIADITACFKPFADPKQLILNSTPKHDEKKRKFDDLEISPTDSSSELMSESKKVKFDSPDDMFLNDPSSVQETKPLVPSELGMYSINSKPSIPSSAGNMPAPNESTDSGMNIWDWNYWESL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).  Required for transcription of genes encoding galactose-metabolizing enzymes.  Essential for normal growth on nonfermentable carbon sources, for sporulation and mating.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 15, Mediator complex subunit 15, Transcription regulatory protein GAL11.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 15 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZBTB1_HUMAN
Sequence: MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESLQLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTGSRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDELEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAGETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT
What is the function of this protein?
Acts as a transcriptional repressor (PubMed:20797634).  Represses cAMP-responsive element (CRE)-mediated transcriptional activation (PubMed:21706167).  In addition, has a role in translesion DNA synthesis.  Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (PubMed:24657165).  Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 1.
Protein: Y2009_YERP3
Sequence: MLCAIYRSPKRDQTYLYIEKKDDFSRVPAELLASFGKPQFAMLLALNERKTLATADVEKVKNALIEQGFYLQVPPPPESLLKMHLGETKA
What are the official names of this protein?
YcgL domain-containing protein YpsIP31758_2009.
Protein: OXLA_BOTFO
Sequence: ADPRNPLEECFRETD
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme.  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation.  Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation.  These different effects are probably due to different experimental conditions.
What are the official names of this protein?
L-amino-acid oxidase Bfon20, LAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG_BUCAT
Sequence: MIPKKIIIMAGGSGGHVFPGLTIARYLIEKGWLVNWIGTKNSIESRIIPKYGIKIHYISIKGLRNTSLKNLIISPIYILRAYYAVKKIIKTWSPDIVLGMGGYVSGPGGVASWNCNIPLLLHEQNKIAGITNKWLSRISTKNMQASPGVLRNAEVVGNPVCQSIIKVPNPINRFKNRTGLLRVLVIGGSQGSSILNRILPEVSFLLKEKIIFWHQTGNYELEKTKKKYNKLRLNQNLITSFIKNIASAYEWADLIICRSGALTVSEISIVGLGAIFIPYPHKDKQQHRNAEDLELIGAAKIIDQSNLNTKLIVNILNSLDRDKLFIMAKKAHSLGVRDAIFNIFNVINKISKKT
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL19_PARDP
Sequence: MNLIAQLEAEQIAALGKDIPDFKAGDTVRVGYKVTEGTRTRVQMYEGVVISRKGGGIGASFTVRKISFGEGVERVFPLYSTNIDSITVVRRGRVRRAKLYYLRDRRGKSARIAEVSNYKPKADAKA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PHNW_LYSSC
Sequence: MSNYKLLTPGPLTTTKTVKQEMLKDRCTWDDDYKNVTQVIRKQLLNLAQVDEPHYTAVLMQGSGSFVVESVLTTAVGEDDKLLIITNGAYGERIVEMAKVLRLALVVYSVPYDKQPSSLEVQALLEKDASITHVAVVHCETTTGILNPIKEIGEVVYSFNKTFIVDAMSSFGGVPMDLSDLHIDFCISSANKCIQGVPGFGFVIAKTNILEKCKGQARSVALDLYSQWEVMKKDGKWRFTSPTHVVAAFAKALEELVEEGGVNARYQRYADNNLLLRSRLSVLGFEAYISEELQSPIITTYLFPHKEFSFEHFYQEMKKAGFVIYPGKLTDVDTFRIGNIGDIYEEDMQALCEVIENYMVVKNNEN
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: SEC11_DICDI
Sequence: MNDIISKINPFSSIPKHQIAQQIVNFGLIVATALMIWKGLMIFSGSESPIVVVLSGSMIPAFFRGDLLYLNMEDGPFRVGEIVVFKIEGKEIPIVHRILQIHEKEDGLYDIRTKGDNNNVDDVGLYSPGQRWLSRDHIIGRAKGFLPSVGMVTIVMHDYPQLKFFLVFVLAVFVLSTRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.
What are the official names of this protein?
Signal peptidase complex catalytic subunit sec11.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: RPOA_XYLFM
Sequence: MTVTISQVLRPRGPQIERLTENRAKVVLEPLGRGYAHTLGNALRRVLLSSIPGSAITQVEIDGVLHEYTTVEGLQEDVLEVLLNLKDVAIRIHSGDTATLSLFKQGAGVVTAADIKTDHNVEIINDGHVICHLTKDTTINMRLKVERGFGYQPAVVRRRPDDENRTIGRLILDASFSPVRRVAYVVEAARVEQRTDLDKLIIDIETNGTIDAEEALRTAADILTDQLSVFGDFTHRDRGTVKPASSGVDPVLLRPIDDLELTVRSANCLKAESIYYIGDLIQKTEVELLKTPNLGKKSLTEIKEVLGQRGLGLGVKLENWPPPGVSQYGMLG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SR542_HORVU
Sequence: MVLAQLGGSISRALAQMSNATVIDEKVLGECLNEISRALLQSDVQFKMVRDMQTNIRKIVNLETLAAGTNKRRIIQQAVFTELCNMLDPGKPAFTPKKGKPSVVMFVGLQGSGKTTTCTKYAYYHQRKGFKPSLVCADTFRAGAFDQLKQNATKAKIPFYGSYMESDPVKIAVEGLERFRKENSDLIIIDTSGRHKQEAALFEEMRQVAEATKPDLVIFVMDGSIGQAAFDQAQAFKQSASVGAVIITKLDGHAKGGGALSAVAATKSPVIFIGTGEHIDEFEIFDVKPFVSRLLGMGDLSGLMDKIQDVMPADQQPELLAKLAEGTFTLRLLYEQFQNLLKMGPIGQVFSMLPGFSSELMPKGHEKEGQAKIKRYMTIMDSMTAAELDSTNPKLMTESRIIRIARGSGRQIRDVTDMLEEYKRLAKMWSKMKGLKMPKNGKMSDLSQNLNIQQMTKALPPQVLKQMGGMGGLQALMKQMGGKDMSKMLGGMGLGGD
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).  As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane.  Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.  Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA.  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA.  SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER (By similarity).  Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP54 2, Signal recognition particle 54 kDa protein 2, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_XYLF2
Sequence: MSSSSIEDIKGKSHRLRGSLLESLANPTTGALGESDQTLIKYHGSYQQDDRDLREERRRQKLEPAYQFMIRTRTPGGVITPQQWLQLDAIATRYANHSLRVTTRQAFQFHGVIKRELKTTMQAINAALIDTLAACGDVNRNVQVAANPLLSRAHADLYTDAAHLSEHLLPNTRAYYEIWLDEKKVAGAGEEEEPIYGPHYLPRKFKIGFAAPPINDVDVFANDLGFIAVIVDNTLLGYNVTIGGGMGTTHGDPDTWPRVGNIIGFITRADLITISTAIVTTQRDFGNRTLRKRARFKYTIDDRGLDCIVGEIQQRAGITLQPARPFVFEHNGDRYGWIEGEDGHWHLTLSLPAGRIADTEGSTLLSGFREIAQLGIGEFRMTPNQNVVIAGISPGQRAAIDALVTQYGLDTGNRAPTALGRHAMACVALPTCGLAMAEAERYLPDFNAKLQPILEKYGLAEAPILLRISGCPNGCSRPYLAEIALVGKAPGRYNLMLGGDQRGQRLNTLYRENITETEILAALEPLLGRYQQKRLPSEGFGDFLHRTGIIALPPYPTHRHVISSTLQA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RECO_YERPA
Sequence: MDGWQRAFVLHGRPYSETSLMLDLFTEGEGRMRVLAKGARGRRSNLKGCLQPFTPLLVRWSGRGEVKTLRSAEPVSLALPLSGSMLYSGLYVNELLSRVLEHQTSYSALFFDYLHCLQALAGSDGSPEHALRQFELAMLANLGYGVDFLHCAGSGQPVSDTMTYRYREEKGFIASLVVDHYSFTGRQLLALANREFPDADTLRAAKRFTRIALKPYLGGKPLKSRELFRQFVIKPPADPSP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: Y1762_FUSNN
Sequence: MKIIFSPSKEMREENIFENKKIEFTESKFKDKTNILIKILSKKSINEIENIMKLKGELLNNTYKDIQNYDKLKYIPAISMYYGVSFKELELEDYSEKSLKYLKNNLLILSTLYGASLAFDLLKKYRLDMTMSITDKGLYNFWKKDVNDYISNILNKDEILLNLASSEFSKLIDNKKISMINIDFKEEEDGTYKSISIYSKKARGKFLNYLVKNQVSNLEEIIKIELDGYNINKDLSDEKNFIFTRKNS
What are the official names of this protein?
UPF0246 protein FN1762.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.