PharMolix/UniProtQA huggingface dataset:
Protein: TAT_HV1H3
Sequence: MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRPPQGSQTHQVSLSKQPTSQSRGDPTGPKE
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: SYS_ACIF5
Sequence: MLDPSLLRSSPETVAAGLARRHFTLDVAALNALDQQRKALQIQLEQLRNARNEASRQIGQARRQGLDTGAMQAAAASNGEEIKTLEQSLERTLAEWDTLTIGLPNIPQDSVPDGRDEADNVVLRHWGSPSTFAFPPRDHVELGEALGIIDFAAGARLAGTRFVVLRGAGARLERALTQFMLDLHTTEHGYTEIAPPFLANADSLYGTGQLPKFEEDLFALRDDPYYLIPTAEVPLTNLLRGEIVASLPQRFCAYTPCFRREAGAYGRDTRGMIRQHQFDKVELVQIVRPEDSAQAHETLTAHAEKVLQLLELPYRVTALCAGDLGFSAAKTYDLEVWLPGQNQYREISSCSNFESFQARRLQLRYRAEDGKPQLVHTLNGSGLAVGRTLVALLENHQQADGRIRIPAALRPYLGGMTVIQA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARB_HELPJ
Sequence: MAKNKVLGRGLADIFPEINEVYEQGLYERANRVVELGIDEVMPNPYQPRKIFSEDSLEELAQSIKEHGLLQPVLVVSENGRYHLIAGERRLRASKLAKMPTIKAIVVDIEQEKMREVALIENIQREDLNPLELARSYKELLESYQMTQEELSKIVKKSRAHVANIMRLLTLSSKVQNALLEEKITSGHAKVLVGLEEEKQELILNSIIGQKLSVRQTEDLARDFKINANFDNKKHGFKQTQTLIAEDELERFNQSLWDRYKLKAALKGKKIVLRCYKNSLLEAFMKKMMS
What is the function of this protein?
Involved in chromosome partition.  Localize to both poles of the predivisional cell following completion of DNA replication.  Binds to the DNA origin of replication (By similarity).
What are the official names of this protein?
Probable chromosome-partitioning protein ParB.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
Protein: LPXK_BORA1
Sequence: MSLNNYWSRLLQTQWRDGGWLSRLLHPLSRLVDRSVRLKREAYRDGRKQAWRAPVPVVVVGNIYVGGTGKTPVVVAVLEGLRARGYTPGMVSRGYGARIQGPPRVGQGQLDPAAFGDEPALIAAATGAPVAVHPRRALAAQALLAAHPEIDVIIADDGLQHLALARDIEIVVQDERGTGNGLLLPAGPLREPPARLNEVDAIITNLNTGPAQVAQTGAARHWAMWLEPLDAQRVTDGKRQALSAFRGKKIAAAAGIGNPGRFFRTLESAGLSPSPRLALPDHYDFSRSPFHDVRAEAIFITAKDAIKCARLKDTRLWSVQVRACFSDPDFLDWLDARLRNLP
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: GB_HHV8P
Sequence: MTPRSRLATLGTVILLVCFCAGAAHSRGDTFQTSSSPTPPGSSSKAPTKPGEEASGPKSVDFYQFRVCSASITGELFRFNLEQTCPDTKDKYHQEGILLVYKKNIVPHIFKVRRYRKIATSVTVYRGLTESAITNKYELPRPVPLYEISHMDSTYQCFSSMKVNVNGVENTFTDRDDVNTTVFLQPVEGLTDNIQRYFSQPVIYAEPGWFPGIYRVRTTVNCEIVDMIARSAEPYNYFVTSLGDTVEVSPFCYNESSCSTTPSNKNGLSVQVVLNHTVVTYSDRGTSPTPQNRIFVETGAYTLSWASESKTTAVCPLALWKTFPRSIQTTHEDSFHFVANEITATFTAPLTPVANFTDTYSCLTSDINTTLNASKAKLASTHVPNGTVQYFHTTGGLYLVWQPMSAINLTHAQGDSGNPTSSPPPSASPMTTSASRRKRRSASTAAAGGGGSTDNLSYTQLQFAYDKLRDGINQVLEELSRAWCREQVRDNLMWYELSKINPTSVMTAIYGRPVSAKFVGDAISVTECINVDQSSVNIHKSLRTNSKDVCYARPLVTFKFLNSSNLFTGQLGARNEIILTNNQVETCKDTCEHYFITRNETLVYKDYAYLRTINTTDISTLNTFIALNLSFIQNIDFKAIELYSSAEKRLASSVFDLETMFREYNYYTHRLAGLREDLDNTIDMNKERFVRDLSEIVADLGGIGKTVVNVASSVVTLCGSLVTGFINFIKHPLGGMLMIIIVIAIILIIFMLSRRTNTIAQAPVKMIYPDVDRRAPPSGGAPTREEIKNILLGMHQLQQEERQKADDLKKSTPSVFQRTANGLRQRLRGYKPLTQSLDISPETGE
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of the virion envelope.  Participates in viral entry through an RGD motif that binds ITGAV-ITGB3.  Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: MET22_HUMAN
Sequence: MVQLAPAAAMDEVTFRSDTVLSDVHLYTPNHRHLMVRLNSVGQPVFLSQFKLLWSQDSWTDSGAKGGSHRDVHTKEPPSAETGSTGSPPGSGHGNEGFSLQAGTDTTGQEVAEAQLDEDGDLDVVRRPRAASDSNPAGPLRDKVHPMILAQEEDDVLGEEAQGSPHDIIRIEHTMATPLEDVGKQVWRGALLLADYILFRQDLFRGCTALELGAGTGLASIIAATMARTVYCTDVGADLLSMCQRNIALNSHLAATGGGIVRVKELDWLKDDLCTDPKVPFSWSQEEISDLYDHTTILFAAEVFYDDDLTDAVFKTLSRLAHRLKNACTAILSVEKRLNFTLRHLDVTCEAYDHFRSCLHALEQLADGKLRFVVEPVEASFPQLLVYERLQQLELWKIIAEPVT
What is the function of this protein?
Protein N-lysine methyltransferase.  Trimethylates KIN at Lys-135 (in vitro).
What are the official names of this protein?
Methyltransferase-like protein 22.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DIDB_CERVI
Sequence: NSAHPCCDPVTCKPKRGEHCISGPCCRNCKFLSPGTICKKARGDDMNDYCTGISSDCPRNPWKD
What is the function of this protein?
Inhibits ADP-induced human platelet aggregation.  Antagonist of alpha-IIb/beta-3 (ITGA2B/ITGB3) (By similarity).
What are the official names of this protein?
Disintegrin CV-11-beta, CV11-beta.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIE_ESCF3
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRMVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTEKEKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHILPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMEDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: AXE1_ASPOR
Sequence: MILLSYLLTYLLCALTCSARAIHNGRSLIPRAGSLEQVTDFGDNPSNVKMYIYVPTNLASNPGIIVAIHYCTGTAQAYYQGSPYAQLAETHGFIVIYPESPYEGTCWDVSSQATLTHNGGGNSNSIANMVTWTTKQYNADSSKVFVTGTSSGAMMTNVMAATYPNLFAAGVAYAGVPAGCFLSTADQPDAWNSTCAQGQSITTPEHWASIAEAMYPDYSGSRPKMQIYHGNVDTTLYPQNYEETCKQWAGVFGYNYDAPESTESNTPEANWSRTTWGPNLQGILAGGVGHNIQIHGDEDMKWFGFTN
What is the function of this protein?
Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone.  Displays the greatest hydrolytic activity toward alpha-naphthylacetate (C2), lower activity toward alpha-naphthylpropionate (C3) and no detectable activity toward acyl-chain substrates containing four or more carbon atoms.
What are the official names of this protein?
Acetylxylan esterase A.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 1 (CE1) family. AxeA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTS_BURTA
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEADGDMAKAEELLRVKLGNKASKAASRVTAEGVVASFVGANAGALVELNCETDFVAKNDDFNAFAKTVAELVATQNPADVAALSALPLDGKTVDEVRLALVGKIGENISIRRFVRFETSNKLATYLHGSRIGVIVEYTGEQEQVGKDVAMHVAAMKPVSLSSDDVPAELIEKERRVAEQKAAESGKPAEIVAKMVDGSVQKFLKEVSLLNQPFVKNDKQTIEQMLKASNAAVQKFALFVVGEGIEKRQDDFAAEVAAQVAAAKQQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P30II_HTL1A
Sequence: MALCCFAFSAPCLHLRSRRSCSSCFLLATSAAFFSARLLRRAFSSSFLFKYSAVCFSSSFSRSFFRFLFSSARRCRSRCVSPRGGAFSPGGPRRSRPRLSSSKDSKPSSTASSSSLSFNSSSKDNSPSTNSSTSRSSGHDTGKHRNSPADTKLTMLIISPLPRVWTESSFRIPSLRVWRLCTRRLVPHLWGTMFGPPTSSRPTGHLSRASDHLGPHRWTRYRLSSTVPYPSTPLLPHPENL
What is the function of this protein?
p13II increases mitochondrial permeability to monovalent cations, producing a rapid, membrane potential-dependent influx of potassium.  This could involve a channel-forming activity.  Interferes with cell proliferation and transformation and promotes apoptosis induced by ceramide and Fas ligand, probably using the Ras signaling.
What are the official names of this protein?
Accessory protein p30II.
What is the protein family that this protein belongs to?
Belongs to the HTLV-1 accessory protein p30II family.
What are the subcellular locations of this protein?
[Isoform p30II]: Host nucleus, host nucleolus. SUBCELLULAR LOCATION: [Isoform p13II]: Host mitochondrion inner membrane.
Protein: FLGB_AQUAE
Sequence: MDLFRGVNLYKKYINFTWKRHKVLLGNLANADTPNYKRRDLIFFLEPPTIPLKTTHNKHVKNFRKFEERLVVFKNGLQGNDRNNVSIERELSEIVKNKLAYETYLKFAMGSLNTLNRVIKGRAE
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RS20_HELMI
Sequence: MPNIKSAIKRVKIARERTLKNASARSALRTTLKRFEAALASADVDNARAALAKAVRALDKAAAKGLIHKNTASRKKSRITKRFNKAVV
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PVK3_EUBSB
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, EubSp-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL18_NEIM0
Sequence: MDKHTTRLRRARKTRARIADLKMVRLCVFRSNNHIYAQVISAEGDKVLAQASTLEAEVRGSLKSGSNVEAAAIVGKRIAEKAKAAGVEKVAFDRSGFQYHGRVKALAEAARENGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CAZA1_MOUSE
Sequence: MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNSRFLDPRNQISFKFDHLRKEASDPQPEDVDGGLKSWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPSAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEVQTTKEFIKIIESAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.  May play a role in the formation of epithelial cell junctions (By similarity).  Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-1, CapZ alpha-1.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS16_PSE14
Sequence: MLTIRLALGGSKKRPFYHLTVTDSRNARDGSHKEQVGFFNPVARGQEIRLSVNEERVNYWLSVGAQTSERVAQLLKEHNKTKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SPAK_SHIFL
Sequence: MSNINLVQLVRDSLFTIGCPPSIITDLDSHSAITISLDSMPAINIALVNEQVMLWANFDAPSDVKLQSSAYNILNLMLMNFSYSINELVELHRSDEYLQLRVVIKDDYVHDGIVFAEILHEFYQRMEILNGVL
What is the function of this protein?
Required for surface presentation of invasion plasmid antigens.  Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells.  Has been shown to chaperone IpaA, IpgB1, OspC3 and probably also OspB.
What are the official names of this protein?
Surface presentation of antigens protein SpaK, Class 1B type III secretion system chaperone spa15.
What is the protein family that this protein belongs to?
Belongs to the SpaK family.
Protein: EGAL1_CAEEL
Sequence: MEEAKNMALLFFMDHLMQKNGRRTIHDLSCQFGARGFSEEMRNAVGTTQEGLTEFLQGHPSLFTVEGDQVILNGHNDLNAKNNPLLQSGIRSRNYEKEAVDFFVTKLTKFGPELQIKSLLGHRSQAAPEVRLVSGRHLKEFCEFLQSQVDYFVVEGDRVRLKNMPEPDENAIEMDDEGRPLAGVKAKQAAVEYLKSVLEQNEDQPIPLDQFYQNFCQRFSHTIRQDVATNPKELLQFLKLNRGLFFIRSNKVSLVKNRLNEDGSENGSDEGEETNNNGMFPLDQSALTRIHFVKALKPAQDLISRLWQDINNMEKKVVGLDLKTVTVGVDGEIFLSLGVIATTSQIGIFDLASSDVIILESGFKGILESEKVVKVIHDARRVASLLAHKYAVHMRNVFDTQVAHSLLQHEKFNKSLNEMRPISFINLQRVYYPQSIMLSDVTPRKMSMCPNWGVRPITEEFQLTIVEEAHCLLSALYQSLSNLIPVHLRGVFEDKCIEVNHPEVLLASPNRPPPQPFISSPYRASTRRDVRNGGSIMQSFSPAPYAAAPRPQMSDACTQTFSTGDIEVLNVFYE
What is the function of this protein?
Part of a complex with bicd-1 and dlc-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells.
What are the official names of this protein?
Egalitarian protein homolog.
What are the subcellular locations of this protein?
Nucleus envelope. Note=Probably recruited to the nuclear envelope by unc-83.
Protein: RECF_STRT1
Sequence: MWLEKIDIQHFRNYSEASVSFSPHLNIFLGRNAQGKTNILEAIYFLALTRSHRTHLDKELIQFQQNSLKLNGIVHRHSGNLPLEINLSNKGRVTKVNYLKQAKLSDYIGHMTVVLFAPEDLQLVKGSPSLRRKFIDIDLGQIKPVYLSDLSNYNHVLKQRNAYLKSTDKVDINFLSVLDEQLADFGARVIKHRLEFIKQLEEEADGHHSILSNQIERLKISYESNIPIQNSKDIREAFLTTLNQNHKRDIFKKNTGVGPHRDDLKFYINDMNASFGSQGQQRSLILSLKMAEIALIKKVTEEFPILLLDDVMSELDNHRQLKLLESIDEEVQTFMTTTSLDHLSNLPPNLKTFLVKNGTIYEKQVD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPD1L_XENTR
Sequence: MALAGPLKVCIVGSGNWGSAVAKIIGHNVKNLKKFASTVNMWVFEENINGRKLTEIINTEHENVKYLPGYKLPENVVAVPNLSDAVKDADLLIFVIPHQFIHKICQEISGKVHRNALGITLIKGIDEGPEGLRLISDIIREKMDIDVSVLMGANIANEVAAEKFCETTIGSKNKEHGLLFKELLQTPNFRITVVEDADTVELCGALKNIVAVAAGFCDGLGCGDNTKAAVIRLGLMEMIAFANVFCKGPVSIATFLESCGVADLITTCYGGRNRKVSEAFVKSGKSIEELEKEMLNGQKLQGPQTSAEVYRILQQKNMVNKFPLFTAVYQICYEGKPVEDVISCLQSHPEHM
What is the function of this protein?
Plays a role in regulating cardiac sodium current.
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_LYSSC
Sequence: MTTYTPMMQQYLQVKEDYKDAFLFFRLGDFYEMFFEDAINASQILEITLTSRDAGAKERIPMCGVPHHSAKNYIETLVQKGYKVAICEQTEDPKQAKGVVKREVVQLITPGTIMEGKTLEGKSNHFIGAAEQLDDTTFGYAYLDLSTGEAVASSIEGDGKALLMQMQAYGIRELIVTDSLQLLLAEHAANAAIVLSVEADEMTMDKAASYVEAVPPALQISCLRLLAYIDKTQMRSLSHIQAFTFNEMKHYLRIDSSSKRNLELIQSIRGGDQKGTLLWLLDDTVTAMGGRKLKQWLHQPLATRSAIESRLAIVTDLLEEYFVRTELQTALKQVYDLERLAGRVAFGNVGGRDLAQLRDSLRQVPAIQQQLMGAGKETLQQIGVALDTCTDVVELLAKAITDNPPITIKEGDVIRDGYHGRLDELRYAARNGKDWIAQLEQEERLKTGIKNLKIGYNRIFGYYIEITKSNIHLADLTRYERKQTLANAERYITQELKEKEALILNAEEESLALEYNLFVEIRDALKEFIPRVQALAASISELDVLLSFASISEKYRFTKPQFHNGRALEIIEGRHPVVEKMLNKQMYVPNDCVLEEQNNMMLITGPNMSGKSTYMRQVALIVVMAQMGCYVPAEKAKLPITDQIFTRIGAADDLAAGQSTFMVEMLESQHAIMHATKNSLMLFDEIGRGTSTYDGMSLAQSMMEYIHDKIGANTLFSTHYHELTALEKDLPRLQNVHVAATEKNGMVVFLHKVKKGAADKSYGIHVAQLAQLPEEILARARVLLENFEAGNEVVAEAQKIAEPPLQMSLFTEEEPMAPAEAEVLKKLEKVNILGTSPMQAMNILYELQQELLNMKK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PURQ_ALKMQ
Sequence: MRFGIVVFPGSNCDIDCYYVLKDELQQEVEYIWHEEELKEGFDCIILPGGFSYGDYLRCGAVAQFSKVMEGVKVYAHAGGLVVGICNGFQILTEAGLLPGALVRNKGLKFICDTTPLKVTEANSPFTNQYQKGEVIQIPIAHGEGNYVVDEVTLAEMKTKGQILFTYGENPNGSTGDIAGICNEGKNVMGLMPHPERASEALLGNVDGKKFFQSIMHYLEGGKNND
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXLA1_ARATH
Sequence: MGSFLFLIVVIFLFSSSVNACDRCLHRSKAAYFSSASALSSGACAYGSMATSFFAGHIAAAIPSIYKDGAGCGACFQVRCKNPKLCSTKGTIVMITDLNKSNQTDLVLSSRAFRAMAKPIVGADKDLLKQGIVDIEYQRVPCDYGNKNMNVRVEEASKKPNYLEIKLLYQGGQTEVVSIDIAQVGSSPNWGYMTRSHGAVWVTDKVPTGAIQFRFVVTGGYDGKMIWSQSVLPSNWEAGKIYDAGVQITDIAQEGCDPCDAHIWN
What are the official names of this protein?
Expansin-like A1, At-EXPL1, AtEXLA1, AtEXPL1, Ath-ExpBeta-2.1.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin-like A subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LACB_ENTFA
Sequence: MKIAIGCDHIVTDTKIAVSDFLKAKGYEILDVGTYDFTRTHYPIFGKKVGEAVMSNQADLGICICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNANVIGFGGKITGEFLICDIAAAFIEAHYHPTEDNEQLIEKINQVEKQHPEQQDAHFFDEFLDKWQRGVYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: 3MGH_RHOP2
Sequence: MMSSRVSAPAPGALGPPLRRRFFARSVHEVAPELIGATLLVEGVGGVIVEVEAYHHTDPAAHSYGGQTARNAVMFGPPGFAYVYRSYGIHWCVNVVCEAEGSASAVLIRALQPTHGVEAMRARRGLDDARSLCSGPGKLAQALGISIAHNGLPLDAPPFAIHRRIGEPDIVTGPRIGITKAADYPWRFGLKGSRFVSVPFK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: ORN_BAUCH
Sequence: MISLHNLIWIDLEMTGLNPEQDRILEIATLITDANLNIIAEGPVLAIHQSEEQLKLMNTWNIRIHTANGLIEKVRKSTLNEETAAAQTIAFLQEWVPAGKSPICGNSISQDRRFLYRYMPILESYFHYRCLDVSTLQELARRWKPKIMAGIKKKNSHKALDDIRESVAELVYYRAHFLLLSSNI
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_PSEPG
Sequence: MSLAEQIEQQQGDAGWSAHLQLRFVQRGDVTRLGAWKHFGPLLVQRPFYPEGSPCHVYVLHPPGGIVAGDRLELNIHLEPGSHALLTMPGASKFYRSIGPTARLTQRFHLAAGSTLEWLPQDSIFFSGARASLASRFSLEPGARLLAWETLCLGRPVMHERFDHGTLDSLLHIELPDEVGLHERLRIAGGHLDKLGGHPLLATFCAAPADQAVLEQVRSLLDELGNPAGATLLGSLLVIRLLDHDNQHLQRTLQRLWHVLRPAILGLPACPPRIWAT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.