PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_RHOPA
Sequence: MRDPVETYMNLVPMVVEQTNRGERAYDIFSRLLKERIIFVTGPVEDGMSTLIVAQLLFLEAENPKKEISMYINSPGGVVTSGLAIYDTMQFIRPPVSTLCTGQAASMGSLLLAAGHKDMRFSLPNARIMVHQPSGGFQGQATDIMLHAQEILNLKKRLNEIYVHHTGQTYKAIEDALERDKFLTAEMAREFGIVDKVIEKRPEDPAPAPKAA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_NEIM0
Sequence: MTAQTLYDKLWNNHVVREEEDGTVLLYIDRHLVHEVTSPQAFEGLKMAGRKLWRIDSVVSTADHNTPTGDWDKGIQDPISKLQVDILDKNIKEFGALAYFPFMDKGQGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSKSMLIAVDGKLKAGVTAKDVALYIIGQIGTAGGTGYAIEFGGEAIRSLSMEGRMTLCNMAIEAGARSGMVAVDQTTIDYVKDKPFAPKGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVLDISSKVPNPAEETDPVKRSGMERALEYMGLEAGTPLNEIPVDIVFIGSCTNSRIEDLREAAAIAKDRKKAANVQRVLIVPGSGLVKEQAEKEGLDKIFIEAGFEWREPGCSMCLAMNADRLTPGQRCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAVTGRFTDIRMMA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PLAP_RAT
Sequence: MASGAARYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLGVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTEADERTASAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGERVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTSFSDPFTGGGRYVPGTSGPSNTVQTADPFTGAGRYMPGSAGMDTTMAGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGSAPEEKKLTEDDLVLLEKILSLICGNASEKPTAQQLQVLWKAINWPEDIVFPALDILRLSIKHPSVNENFCNEKEGDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYASVSEPAKVSECCRLILNLL
What is the function of this protein?
Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (By similarity).  Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (By similarity).  May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (By similarity).  Plays a role in cerebellar Purkinje cell development.  Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis (By similarity).
What are the official names of this protein?
Phospholipase A-2-activating protein, PLA2P, PLAP.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PLAP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Synapse. Note=Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains.
Protein: G3P_BUCAP
Sequence: MTIKIGINGFGRIGRVLFRLAQERENIEVVAINDLLDPKYIAYMLKYDSTHGNFKKDIEVKNNNLIINGKKIRITSIKDPEKLMWDKLLIDVVIESTGLFLTKDTAYKHILSGAKKVVITGPSKDDIPMFVRGANFDKYKGEKIVSNASCTTNCLAPLSKVIDDHFGIIEGLMTTVHASTATQKIVDSASKKDWRGGRGALQNIIPSSTGAAVAVGKVLPNLNGKLTGIAFRVPTANVSVVDLTVRYKKTATYNEICEVVKNASEQKMKGILGYTEDEVVSTDFNGKELTSIFDAKAGLSLNKNFAKLISWYDNETGYSSKVLDLVELVALK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRC_RSVSE
Sequence: MGSSKSKPKGPSQRRRSLEPPDSTHHGGFPASQTPNKTAAPDTHRTPSRSFGTVATEPKLFGDFNTSDTVTSPQRAGALAGGVTTFVALYDYESWIETDLSFKKGERLQIVNNTEGNWWLAHSVTTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHKKLVQLYAVVSEEPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMSQCWRRDPEERPTFEYLQAQLLPACVLEVAE
What is the function of this protein?
This phosphoprotein, required for both the initiation and the maintenance of neoplastic transformation, is a protein kinase that catalyzes the phosphorylation of tyrosine residues in vitro.
What are the official names of this protein?
Tyrosine-protein kinase transforming protein Src, pp60v-src, p60-Src, v-Src.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Protein: DCD_ECOL5
Sequence: MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRREDAKYRNQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: LEUC_HYDCU
Sequence: MSAKTLYDKLWDSHVVREEEDGTALIYIDRQLLHEVTSPQAFEGLRLANRKPWRIDANLATPDHNVPTTAFNSVEDIVDPISRIQVQTLDANTKQFGITEFGIGDVRQGIVHVVGPEEGVTLPGMTLVCGDSHTATHGALGALAHGVGTSEVEHVLATQCLIQKKMKNMLVKVDGKLQPGVSPKDVVLAIIGQIGTAGGNGHAIEFGGQVFRDMSIEGRMTVCNMAIEAGARVGLVAVDEKTVEYVKGRPFAPKAEDWDAAVAAWQDLKSDDNAHFDKVVEMDGSKIEPQVSWGTSPEMVSDVNGKVPNPAHESDDVKAGGIRRALEYMGLEADMAITDIPVDYVFIGSCTNSRIEDFREAAAVLKGRKVASSVEQALVVPGSGLVKRQAEEEGLDKIFIEAGFEWRNPGCSMCLAMNADRLPSGKHCASTSNRNFEGRQGAGGRTHLVSPQMAAAAAVAGHFVDVRDMMKEAS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y584_HAEDU
Sequence: MELVIISGRSGSGKSVALRALEDVGYYCVDNLPFPLIAELASFLLASDCSAVVSLDIRNFPENLTRIDELLHQLSQLTINTKMIFLDCESATLIRRYSDSRRLHPLSNQDLSLASAIELENTLLDPLRQQADYLIDTTHSSPHELAANLRHILRGSTEKELNIVFESFGFKYGLSADADYVFDVRFLPNPHWHAELRAMTGLEQPVIDFLERQTEVHNFIYQTRNYLETWLPMLEKNNRSYLTIAFGCTGGKHRSVFITEQLAKYFQSRGKNVKIRHRSLEKYHKKT
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein HD_0584.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: ALR_CHRSD
Sequence: MSRPLIADIDLDALRRNYCLARDQAPHSRAIAVVKADAYGHGAVACADALRDLAPAFAVACLEEALTLREAGITQPIVLLEGFFDAAELSLIDAHRLWTAVHSDWQIDALLAYRPRQPIPTWLKLDSGMHRLGFAPEAFEARWQRLAAATEHVTDLHLMTHFATADALDAAYFRRQMACIASLRQRLEAPVCLANSPATLAWPEAHGDWNRPGVMLYGSDPLEGANDASRALEPVMTLRSEIIAVRELAEGEAVGYGGRWRASRPSRIGVVAGGYGDGYDRHARDGTPVLVEGQRVPLAGKVSMDMLTVDLTELPEAGIGSPVVLWGEGLPIDEVARHCDTISYTLMTGVLPRVPRRYRNAETG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PDXJ_CAUVC
Sequence: MSLRLGVNIDHVATIRNARGASYPEPVRAAELALIAGADGITAHLREDRRHISDADIAVLTDLCHKRGKPLNFEMAVTDEMVGIALNARPHAACLVPERREEVTTEGGLDVIKGQKRIADATARLRTVGARVSLFIEPDPDQIRACVTAGAQVVELHTGAYCDAARAGETARAEAILKRLKAGAALAHELGLEVHAGHGIDYATVKPVAAIPQIAELNIGHFLIGEAIFVGLPEAIHRMRALMEAARVELEVLA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_STRA1
Sequence: MSDKKTFEENLQELETIVSRLETGDVALEDAIAEFQKGMLISKELQRTLKEAEETLVKVMQADGTEVEMDT
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PATR_THEFY
Sequence: MSERKPPYLRSALDSIPPYRPGRKVVGPDGRSAKLSSNESPFGPLPSVRQAIADAAADLNRYPDPAAAELTAALARRFHVPEEHVALGAGSVGLLQQLLEATAEPGAEVVYAWRSFEAYPLLTGLAGATPIHVPLREETHDLEALAAAVTDRTRMVFVCNPNNPTGTAVRETELAEFLDTVPEHVLVVLDEAYREYVQDPRVPDGVQLYRDRPNVAVLRTFSKAYGLAALRVGFLIGHPQVVDAVRKTLVPFAVNHLAQAAAVASLAAEQELLERVAVTVKERERVRAALLADGWTVPETEANFVWLRLGEDTLDFAAACEQAGIAVRPFAGEGVRVSIGLPDDNDAFLTVARTYPKRN
What is the function of this protein?
May catalyze the transamination reaction in phenylalanine biosynthesis.
What are the official names of this protein?
Putative phenylalanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: C3H34_ORYSJ
Sequence: MAAAAEGDEDPRWRRCNTDCVYFLASPFTCTKGSKCEYRHADGARFNRRNCWYWFKGNCVNPSCTFRHPPLENLNKTKSLADPLSLCSTSVKAANPCYFYYNSHCSKGDNCPYLHEPLTSNDAVGTSCKATTSNPAVSKSYVGDEMVEESKDTITNPCQDTSCHIKEVPVSINPEFGEAEAVSGALETSTDIDEYMKCSAVSDLNSGDSTMDHTEQDERDSSPGFDVLVDDCLSNKSDLEHQLTTESDNKVLHAEYGIRDPVLYDMYYHDPEYYNYEPEFCGLDDRQGYLYLCQPNGAHEHESEITLGHLLPQNTEVTSDEYDRRFFNPRNFTSSVADTNFVHQHTQIRHISKRRPENRKGAKGKKDCIKRSRCLEPKNSTQQIESMPTRQRKDYLMGECPQPANHATFRGRRKKNRGKQQHVLSAKSSEHPTADFTGPKTLAQIKEEKCKSNSSFSHSTACTPNVRSFSDDFEGPKSLTELLMTKSRSSVGK
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 34, OsC3H34.
Protein: AKTIP_DANRE
Sequence: MNPFWSMSTNAGRKRSDGEEQSGSGEQRASPARPPFGKKQLPSIPKNAVPITKAASPASSTQSANGTHASYGPFYLEYSLLAEFTLVIKQKLPGIYVQPSYRSALMWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPKVVFDTPVFHPLVDPVSGELDVRRAFTKWRRNHNHIWQVLMYARTIFYKINTMEPLNPEAAVLYDKDIQLFKSKVVDSVKLCNSHLFDQPKIDDPYAISFSPWNPAVHEEAKEKMFAHKRRPEDFNKGLPVSGLSWVKPGSTQPFSKEDNPLQT
What is the function of this protein?
May function to promote vesicle trafficking and/or fusion.  May also regulate apoptosis (By similarity).
What are the official names of this protein?
AKT-interacting protein, Fused toes protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: UBA5_AEDAE
Sequence: MATMEELKLQIETLQSELCKLKATSAGGAREKIEKMSSEVVDSNPYSRLMALQRMGIVSEYERIRQKSVAVVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQAGLSKVEAAAKTLNFINPDVKILTNNYNITTVESFDKFLNAIKTGGIEEGTPVDLVLSCVDNFEARMAINTACNELSLNWFESGVSENAVSGHIQFIRPGDTACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGIVAGMLVQNTLKYLLNFGTVSDYLGYNALIDFFPKMSLKPNPTCDDRFCIDRQKDYAARPKEERVEEVPEEETPLHEENLYGIELVAEDDTQGSQPSTGTTHSISTGLKLAYEPPASTKHSETTSTTAVSDDVSLDELMAQMKSM
What is the function of this protein?
E1-like enzyme which activates UFM1.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
Protein: GARS_DROME
Sequence: MSLQLLKALPHLRSATTAVRTQIARTTWSEHIATKVFFSTTTTKPTPSAPPPPPPTQPQQPAATTSWGTKKQNRKVKLRSAAAEFIMSNPEIEAQLAPLRERVQEQGNLVRDLKAKGAPEIDVKKAVAELKARKKLLEDKELALTPSVVSFDRAKMEDLLKRRFFYDQSFAIYGGITGQYDFGPMGCALKSNILALWRQYFALEEQMLEVDCSILTPEPVLKASGHVERFADLMVKDVKTGECFRLDHLIKQALEKLSKAKDATPALQAECEDIIIKLDGLNKQELAGVLAKYNIKSPLTGNDLTEPIEFNLMFATQIGPTGLVKGFLRPETAQGIFVNFKRLLEFNQGKLPFAVAQIGNSFRNEISPRSGLIRVREFTMAEIEHFCDPVLKDHPKFGNIKSEKLTLYSACNQMDGKSAAQVQIGEAVASKLVANETLGYYMARIQQFLLAIGIKPECLRFRQHMSNEMAHYACDCWDAEILTSYGWVECVGCADRSAYDLGQHTAATGVRLVAEKRLPAPKTVEVSEIVPNKQALGKTFKKEAKNITDALAKLSLEEITKVEEQLAGDGQYKLTTADGQSHDLGKDTISVKHSTKTVHVEEFIPSVVEPSFGIGRIMYSLLEHSFQCRDGDEQRCYFTLPPLVAPIKCSILPLSNNTDFQPYTQKLSSALTKAELSHKVDDSSGSIGRRYARTDEIAIPYGITVDFDTLKEPHTVTLRDRNTMKQVRVGLEEVVGVVKDLSTARTTWESVTEQYPLFEQQEASK
What is the function of this protein?
Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP).  Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.  Thereby, may play a special role in Ap4A homeostasis (By similarity).  Required for terminal arborization of both dendrites and axons during development (PubMed:17529987).
What are the official names of this protein?
Glycine--tRNA ligase, Diadenosine tetraphosphate synthetase, Glycyl-tRNA synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
[Isoform B]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform A]: Cytoplasm. Cell projection, axon.
Protein: PBPA_AQUAE
Sequence: MKKLVIGILGIVIALFVGLLVFLIPIYKNLPDPKLLESWTPPQASEVYDAKGRLYGTIGIQKRFYVSIDKIPEHVINAFVATEDRNFWHHFGIDPVAIVRAAIVNYRAGRIVQGGSTITQQLAKNLFLTRERTLERKIKEALLAIKIERTFDKKKIMELYLNQIYLGSGAYGVEAAAQVYFGKHVWELSLDEAALLAALPKAPAKYNPFYHPERALQRRNLVLKRMLEEGYITPEQYEEAVNKPLTVKKENKYKFSDYFLDMVKSYVFNKYGEIAYKGRLKIYTTIDLDYQKIAQKSLEEGLKRVAKIIGLPFLPKSEEDMELAYEKEAQLKRLKRGKIYVAKILKYDGNFMKVEIHGKKLKGEIKGLNTEGHKYVFVKYLGGNRAEIIPDLEGSLVSIDVKTGEIKAIVGGRSYAYSQFNRAVKALRQPGSAIKPVIYLSALLKGMTQISTIDASSKPYYDPSKGEDWIPKNYDEKEYGNVTLRYALAHSINTAAVNLLDKVGFELVLEVGKKVGLDNLKPYYSLALGTVEVTPLQLTAAYQVFANLGTECKPFFIKKIVDENGEVLEENVPECEEVLPKPETRVPVDMLRAVVLEGTARRASVLDRIVAGKTGTTDDFQDAWFVGFSPYIVTGVWVGYDVKKSLGKHMSGSRVALPIWIDYMKVVTRMYPNEDFELPPENIVVNINPKDLVLADETCEGVPMVFVKGTEPHITCSDLNAILGLR
What are the official names of this protein?
Penicillin-binding protein 1A, PBP-1a, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: YCF39_TRICV
Sequence: MSLLIIGGTGTLGRQVVLQALTKGYQVRCLVRNFRKANFLKEWGAELIYGDLSRPETIPPCLQGITAVIDTSTSRPSDLDTLKQVDWDGKCALIEAAQAANVKHFVFCSSQNVEQFLNIPLMEMKFGIETKLQQSNIPYTVFRLAGFYQGLIEQYAIPVLENLPILVTNENTCVSYMDTQDIAKFCLRSLQLPETKNRTFVLGGQKGWVSSEIINLCEQLAGQSAKVNKIPLFLLKLVSQIFGFFEWGQNISDRLAFAEILNVENDFSKSTFDLYKTFKVDDSEITQLDDYFLEYFIRLLKRLRDINFEDIQKQKNLII
What are the official names of this protein?
Uncharacterized protein ycf39, ORF319.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Ycf39 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RM36_MOUSE
Sequence: MAALLVRSVVASVVDPFLHLSRLAVKPRVFSSFLLGTLPRAKPCAEVRSVLCGRPLPTLLPSLGFKTKGVIKKRCKDCYKVKRRGRWFILCKTNPKHKQRQM
What are the official names of this protein?
39S ribosomal protein L36, mitochondrial, L36mt, MRP-L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: H962L_ASFP4
Sequence: MGKPTLLEPGHLYNVPAEHKNDVPIHYIITWIKQRLPEFGGAIPTSLADRVLIIKSRTGSGKSTALPVHVFRILRNENTHSFQKYLGRSVICTQPRVLTAVTLAKDIGASTHYPDMILGQTVGYQTKPLTEKPNRGLIYATAGVLLAQLHTMTDDEIASRYAFMIIDEAHERALGIDLMLMYIKSMLERMLQRGSIGALRIPFVILTSATIDTHKYSTYFGIGKENIILVEGRQYGVETHWPLYNTNNYIKTACETALTIHKENIHDRPTEADILIFMPGMAEIRFLSMLLNNANMDLAKEKLPLMLILPIDSEAIAQENEAYLGLKAEIKNLWVKNPLTAKVEKPLRRVIVSTVVAETGLTIETLKYVIDPGWNRSIETYYPEWAGGLITRPAAQSRIEQRKGRVGRVFPGHFYPLYTKHVFEQIPAQQYPEIITEGPGAIFLSIVVETIKKNKEGVFKAEEIDMLDPPPTDALASAIERAIVAGLLTRGEKGLQLTQLGDIASRFSFLSIEEARMCFSGYFWQAAISDIATILAVVSVADKKLTNLLDSKQRNGAMLAEAVLAGIPPFLQNIDNAYTNIHLLLADDLLEGLFIFEGFQHAIVYFINNKVNNVAKHLREWCEKKMLKYSSMVQILARREDILNELAIVGLNPFHQWQNRLASANAETFLKRVCTLKQCMYEAYRLNCFCYDEHRLLYTGRNGIHFSYHDAVIKNPSCIVTPRIMLSPVSKQYMEWRLEPSFVSVLDGFVNVDINFLLPRQEIPNILGGAEDEEEEPPLPIQVFLHKYVKTHFHFSGKSFKELKMKPGQTIKFPETTLINMIPDIPKNVVQTYLEISVCHQYSFKRLIYCETFYTDMDDVQHENSVELIGLPMAAHHLTINDFNKLYHLLKPDGFLMVYDLHQSQEAFWLHSLQDALGHHTIRRDMDFHTIPEWETIFKECGFTPIFSKQPSEHELFIVFKK
What are the official names of this protein?
Putative RNA Helicase B962L.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: SEC11_TUBMM
Sequence: MDALGLSKLRHLKPRQLLSQVLNFALILSTAFMLWKGLSVATDSPSPIVVVLSGSMEPAFQRGDLLFLWNRNLELDSPPTPGTRVGEIVVYNVIGKDIPIVHRVVRKHQGPKTPLHLLTKGDNNHADDTELYARGRWYLDREKEVIGSVVGYVPFVGYVTIMLSEHPWMKTALLGIMGLLVIVQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: FKBP4_RAT
Sequence: MTAEEMKVAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETAMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEDEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYYNDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVHLKSFEKAKASWEMNSEEKLEQSNIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKTQLAVCQQRTRRQLAREKKLYANMFERLAEEEHKAKTEVAAGDHPTDAEMKGEPNNVAGNQAQVKTEA
What is the function of this protein?
Immunophilin protein with PPIase and co-chaperone activities (By similarity).  Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (By similarity).  Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments.  May have a protective role against oxidative stress in mitochondria (By similarity).  Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly.  The PPIase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP4, PPIase FKBP4, 52 kDa FK506-binding protein, 52 kDa FKBP, FKBP-52, 59 kDa immunophilin, p59, FK506-binding protein 4, FKBP-4, FKBP59, HSP-binding immunophilin, HBI, Immunophilin FKBP52, Rotamase.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Shuttles from mitochondria to nucleus; co-localizes in mitochondria with the glucocorticoid receptor (By similarity). Colocalized with MAPT/TAU in the distal part of the primary cortical neurons (PubMed:20133804).
Protein: KDPC_PSEPW
Sequence: MNTYVRPALSLILLLAVVTGALYPLAVTGVAQVVFPEQANGSLVRDEQGQVRGSALIAQDFQGDGWFHSRPSAGAYATVASSASNLSPSNPALAERVAGDAAKLYQAGQGPVPQALLTTSGSGLDPHLPPQAVAYQIPRVAAARQIPVERLQALLEGATLHPLIGPPVVNVLALNQALSKFGL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: F168B_RAT
Sequence: MNPVYSPGSSGVPYANAKGIGYPAGFPVGYAAAPAYSPNMYPGANPTFQTGYTPGTPYKVSCSPTSGAVPPYSSSPNPYQTAVYPVRSAYPQQSPYAQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPATVYPAPIPPPRGSGVTMGMVAGTTMAMSAGTLLTAHSPTPVAPHPVTVPTYRAPGTPTYSYVPPQW
What is the function of this protein?
Inhibitor of neuronal axonal outgrowth.  Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2.  Positive regulator of CDC27.
What are the official names of this protein?
Myelin-associated neurite-outgrowth inhibitor, Mani.
What is the protein family that this protein belongs to?
Belongs to the FAM168 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell membrane; Multi-pass membrane protein. Cell projection, axon. Note=In cortical neurons, predominantly found at perinuclear regions. Expressed in neuronal cell bodies and axonal fibers.
Protein: TRSF_DROHY
Sequence: MDADSSSRSPRDTRTCARPKEKVPYFADEGRERDRVRNLRHRKTSITRPTTSHRGRPMRARSRSYSAERNCCQRRRRSRSCERRHSDTRHKLTTATVTKQRRRRSRSRSRSRSRTPRIITVPVPVPAADYPYAYAWPPPPQAPQFNPMYGAVPYGMPSRPVYPAHPYFAPYPRPRLTFPYRAPPFRPHPRFSYRNQRPAPN
What is the function of this protein?
Member of the regulatory pathway controlling female somatic sexual differentiation, regulated by Sxl.  Activates dsx female-specific splicing by promoting the formation of a splicing enhancer complex which consists of tra, tra2 and sr proteins.
What are the official names of this protein?
Female-specific protein transformer.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Speckled subnuclear compartment.
Protein: RPPH_RICFE
Sequence: MRNSSKKHLDLPYRPGVGMMILNADNHIFVGKRIDTKISAWQMPQGGIVPGETPSIAAMREMLEEIGSDKGYIIAESKCWYSYDVPSFLIPKLWNGNFRGQKQRWFLIRFTGNNEDININTSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFESLIQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.