PharMolix/UniProtQA huggingface dataset:
Protein: ATPD_SHESR
Sequence: MAELTTIARPYAKAAFDVAVEHNAVDTWAEMLTFAALVSENETMQPLLTGSLASTKLAALFISVCGEQINEQGQNLIKVMAENGRLKVLPAVSELFAQYRNEWAKEVEADVVSAAELSSEQKQQISNSLEKRLARKVKLNCSTDAALIAGVIIKAGDLVIDGSVRGKLSRLSEKLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MAP2_CAEEL
Sequence: MPPANGKKGKKGGAAKAVRRIQYRPKSFKHSRFVKHAHFWSAAPEEDFDAILAEMQLADAKTAAKEATKKDAKGGKGKANGSAAATAAPEEAKQAWQAEIAAMKPIDEQFPDGKFPHGIDESPYYLKGKDGRVATDRESNEEKKALDISYEEVWQDYRRSAEAHRQVRKYVKSWIKPGMTMIEICERLETTSRRLIKEQGLEAGLAFPTGCSLNHCAAHYTPNAGDTTVLQYGDVCKIDYGIHVRGRLIDSAFTVHFDPKFDPLVEAVREATNAGIKESGIDVRLCDVGEIVEEVMTSHEVELDGKSYVVKPIRNLNGHSIAQYRIHAGKTVPIVKGGEQTKMEENEIYAIETFGSTGKGYVHDDMETSHYMKNFELADEKIPLRLQKSKGLLNLIDKNFATLAFCRRWIDRLGETKYLMALKDLCDKGIVDPYPPLCDVKGCYTAQWEHTILMRPTVKEVVSRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins (PubMed:15474045).  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) (PubMed:15474045).  Required for germ cell proliferation and/or differentiation (PubMed:15474045).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA1_BACC1
Sequence: MDRIKCTVAYDGMHFCGYQIQPQHRTVQQEIEKALQKLHKGELVRVQASGRTDSTVHAKGQVIHFDTPLSLEEWQWNNALNTMLPDDIVITQVEKKTEEFHARYGVERKEYRYRVLLSKTADVFRRNYVYQYPYPLEINAIRKAIPYFIGTHDFTSFCSAKTDKKDKVRTIYEIELIEQDDELIFRFVGNGFLYNMVRIIVGTLLSVGQGKLDPDSIPEILAKQNRQFAGKMAPGHGLYLWQVNYNN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A 1, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I 1, tRNA-uridine isomerase I 1.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TRUD_COLP3
Sequence: MLIEQAYLHGKPESSGLLRSQISDFQVFEELPFLPCGEGEHLFVHIRKTGANTLFVARELAKYFEVKEQLVSYAGLKDRFAVTEQWFGIHVPGKQEYNLDDLNIEGVEVLSYKRHNKKLRTGALTGNRFELILREVTAIKAFTERWQKIVEQGVPNYFGEQRFGIGGGNIERALSLFSGQKVKDKKKRGMYLSAARSHIFNSVLNERIQQQCFDKVAVGDVLMLAGTQSVFHLDEVDSAIQQRFTDKDVDITAPMWGAGELMTSNAPQVLEQEVATKNLEFCEGLPRFGLKQERRRIRLTVSDTDIELLSAEEDSAQEESNAVKISFFLPAGCYATTVLRELLNYQDMTTRIDKRETAVNSNQQDSA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: Y932_POLAQ
Sequence: MASVLNEQSLQQLFISARTHHTWKNTPVSDEQLKQIYDLFKYAPTSVNCSPARIVFVKSAAEKERLLQCVNPGNVEKTKNAPVTAIIGMDLDFYEQLPKLFPHVDAKSWFVGKDTFIEQTAFRNSSLQGAYLILAARAIGLDCGPMSGFDADKVNAAFFPDGRVKVNFLVNIGYGDESSLMPRQPRPSFDEACRIL
What are the official names of this protein?
Putative NADH dehydrogenase/NAD(P)H nitroreductase Pnuc_0932.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: RS7_ALISL
Sequence: MPRRRVIGQRKILPDPKFKSELLAKFVNIVMVDGKKSTAEKIVYGALELMAEKSGKDHLAVFEEALENIRPSVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWLVEAARKRGEKSMAQRLANEMLDASENKGTSVKKREDVHRMADANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL4_MYCS2
Sequence: MTLKVDVKTPAGKTDGSVELPAELFDVEPNIALMHQVVTAQLAAKRQGTHSTKTRGEVSGGGKKPYRQKGTGRARQGSTRAPQFTGGGTVHGPKPRDYSQRTPKKMIAAALRGALSDRARNDRIHAVTELVEGQTPSTKSAKTFLGTLTENKKVLVVIGRTDEVGAKSVRNLPGVHVISPDQLNTYDVLNADDVVFSVEALNAYISANSKEGASV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SDI2_ARATH
Sequence: MMMMIQRRGGERQDSSAAAYNVVHKLPHGDSPYVRAKHVQLVEKDAEAAIELFWIAIKARDRVDSALKDMALLMKQQNRAEEAIDAIQSFRDLCSRQAQESLDNVLIDLYKKCGRIEEQVELLKQKLWMIYQGEAFNGKPTKTARSHGKKFQVTVEKETSRILGNLGWAYMQLMDYTAAEAVYRKAQLIEPDANKACNLCTCLIKQGKHDEARSILFRDVLMENKEGSGDPRLMARVQELLSELKPQEEEAAASVSVECEVGIDEIAVVEGLDEFVKEWRRPYRTRRLPIFEEILPLRDQLAC
What is the function of this protein?
Involved in the utilization of stored sulfate under sulfur-deficient conditions.
What are the official names of this protein?
Protein SULFUR DEFICIENCY-INDUCED 2.
What is the protein family that this protein belongs to?
Belongs to the MS5 protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS8_ENDTX
Sequence: MIIDPISDMFTRIRNANLKLHEKVDVPSSKLKLGIAKILKEEGYISNYEIKGIENQTQSVLRIHLRYTSKGKVVLQGIKRISKSSLRIYKGHSDVPRTIGGLGVTIISTSKGLMTDGQARKDKIGGEVIGCVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ADN1A_DANRE
Sequence: MFQLPVNNLTRLRKARKKVKRLLSDIGLDYCKEHVEDYKDVDPDDSDDSNESHLDLCTWDPTWTKSQDYRTKQFCCSDCPFASKYFSAYKNHFRNVHREDFESRILLNCSYCTYSGNKRTLETHVRLFHMPHNVMRQGVVGPHGAPVGAKDGMRVDKPMLGDRKELPVYYCKKCTYRDRLYNVVRRHIYREHFQHVATPYLGKNSEKQVNSGEAQANSHGIHCKSCHFTPRSYEALVQHVIEFHERIGHQVTAMIGHTNVIVPRLQTNPIQRGVPITSGVRPQTPQMNRFSMPKVVGLPVGNHFKQSLAGNSVPGQPVRVTLPDKAFVSSAVSHSHSGKHLGGFGVHGAAHLNAQSASFSPSLKSLPLSSSVHAATATLTSLQAKKASANALNTSQTQKWKICTICNELFPESAYSAHFEKEHQAEKVRAMAKYIMKIHNFTSKCLYCNRYLPSDSLLNHMLVHGLSCPHCHSTFHEVEKIVAHNRLAHPNEQGDQPTGSPLTFDLTLQQGNLKNVQLLVTTYNMKETPEAAAAAAAANQLSQNSAMPKPVKVSVRQPDTQSDSLVRNMSQSPVSQKKEVGKTLCPLCFTILKGPISDALAHHLRDSHQVLQTLHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVCQTPKGSKPITTGLRSPGAGSLKRELVTPDPSDPKRRKMVDQSRFYPTGFAEKPEEPIVLALDPKGYGDKSYEVRKAFLTAYFNRHPYPSQREVEKLAASLWLWKSDVASHFGNHRRLCDRDFTSRKPVVLLGFNMRLLSQIKHDMSFDDSCLFEVFDDEKSGYSRTSSFRLKSPIGFPADFIGSKQPLNTGQSSQSNCAFKTCPGSSSEPIAIDSDSDSELEVIPNENVSQHTPALRPSIVQSQTKGALLRESLRCERDVRANRSSPRVGPKVLDGSVSSSSPDEATWSGNMSSEESHYIPAGRFEVKGKKVGLLGR
What is the function of this protein?
May be involved in transcriptional regulation (PubMed:23071114, PubMed:32533114).  Positively modulates wnt-beta-catenin/ctnnb1 signaling (PubMed:32533114).  Required for embryonic neurogenesis (PubMed:32533114).  Required for progression through late erythroid differentiation (PubMed:23071114).
What are the official names of this protein?
Activity-dependent neuroprotective protein a, ADNP homeobox protein a.
Protein: SYMC_NOSCE
Sequence: MKKKFLVKKIITSALPYVNNQPHLGNIIGCVLSADMYARFCRKNNEDVVFLSGTDEYGTAIEMAAFAQNKTPLQICEENRIIHKKIYDWFNIDFDFFGHTTSTAHTKNVQDFFNKIHNNGFFTEQEIEQFFCDKCQIFLADRYVVGTCKFCKYTDAKGDQCDGCGHTYKSLDLIDAKCTLCHSFPNIKSTRHLFFDFNNFKDKLQKLFNTNSQYWSENGKQITKSWLDQELLPRCMTRDLKNRWGVPVPLKDFEEKVFYVWFDAVIGYFTFYKEYVAARSESKELDKNNVFATDNILQDCELVQFMGKDNVFFHTIVFPSLIFATNDSYPLIKKLSVTEFLLFENEKFSKSRGHGIFGLDLVDNTMGQSCLWRYYLAKIRPEKCDSNFSFTHFTNVIDADLNNNIGNFCNRVLKYIKNKNDKLISIDKLEHRDDLMVQTIDKIYKEYLTSFSAIRIREALEKILEISKVGNEYVQQVVSSKIEVPKGFQVAFSIVVLIGQLLEPFIPVSSEKLLKMCNRKKENFCESFYIIKSAEIGDDIKPLFNKLDDSLIERIKNFKK
What are the official names of this protein?
Probable methionine--tRNA ligase, cytoplasmic, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_PSELT
Sequence: MSLSNLPTEMVNPKTRNLDARDTFEILKLINEEDALVALAIREVLTEIDKVVQMCINCLEKNGRVFYVGAGTSGRVAYVDAVELIPTYSLQEGVFIPIIAGGTQALGKSVEGVEDDEEGGKNDLFSYKPSEKDVVIGIAASGRTPYVAGALRYAKQCGCKTALICNVRKPLLAEYADVVIAAETGPEVVAGSTRMKAGTAQKMILNMISTTVMVKMGKVYDNLMVDVMVLNEKLRERAQNIVTHITGVDKQTAEIYLKKADYNVKVAVLMILSKNDVEECRKILQDQSNLRKALQIAVR
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: PEX5_PICAN
Sequence: MSFLGGSECAANANPLAQFFKQSQHDTSLEQSLRNSAHDTHQNAQIRAPVAMNEAERAHMEQFMNQSTPFNFQPMANELRMIQPDLQTQTTPALRGPRAQNPVPLQIPGQAQPQVSGWSSEFQNTATSQVTHSPSPVSQVRMRSMGMAPRLHLRPFSSANGPIQASSMTNSVMQEDTSQQVDWEQQFKEMEEMEEMEEATAAMQQPAEETVSAQESAFDQVWDNIQETYADNMLSNDEFQAQWEKDFEKYAQTRLNYGEYTFEENNQFRNNLDAYEIGIKLMESGAKLSEAALAFEAAVEQNPGHVDAWLRLGQVQTQNEKELAGIAALEKCLELSPQNLVALMTLAISYINEGYDNAAFATLERWIETKYPEVAERARNANPDIQADDRFSLNKRVTQLFIKAAQLSPEGANMDSEVQTGLGVLFYSMEEYSKTLDCFQAAIEHNPNDALAWNRLGASLANSNKPEQAIEAYSRTLQLNPNFVRARYNLGVSFINMGMYRDAVDHLLTGLSMHEVESLDGSSSVARSNQSTSLIETLKRAFLAMDRRDLIDKVKPGLNVESFRKTYDI
What is the function of this protein?
Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type).  Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins.  PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle.
What are the official names of this protein?
Peroxisomal targeting signal receptor, PTS1 receptor, PTS1R, Peroxin-5, Peroxisomal protein PAH2.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13).
Protein: MTNN_SALAR
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTLTLGGCEIYTGQLNGTDVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLASTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEYCIRELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPNAVAVEMEATAIAHVCYNFKVPFVVVRAISDVADQQSHLNFDEFLAVAAKQSTLMVETLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: CYB_PROCE
Sequence: MTNIRKSHPLMKIVNDAFIDLPAPSNISWWWNFGSLLGVCLMMQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHIGRGLYYGSYTYTETWNVGIILLFAVMATAFMGYVLPWGQMSSWGATVITNLLSAIPYIGTDLVGWIWGGFSVDKATLT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURC_VIBA3
Sequence: MTIEHTQDLAQIRAMVPEMRRVKSIHFIGIGGAGMSGIAEVLLNEGYQITGSDIAQNPVTERLVSKGATVYVGHQASNVADASVVVVSTAINEENPEIIAAREARTPIVRRAEMLAELMRFRHGIAVAGTHGKTTTTALVTQIYSEAGLDPTFVNGGLVKSAGTNARLGSSRILIAEADESDASFLHLQPMVSIVTNIEADHMDTYGGDFETLKQTFIDFLHNLPFYGQAVMCVDDPVVRELIPQVSRQVITYGFSEDADIRIENYVQEGQQGKFTVVREGKANLDITLNIPGRHNALNASAAIAVATEDDISDEAILKAMAGTEGTGRRFDHLGEYETGKGVAMLVDDYGHHPTEVDVTIQAARSGWTDKRLVMIFQPHRYSRTRDLYDDFANVLEQVDVLILLDVYSAGEKPIAGADGRSLSRTIRGRGKIDPIFVADINALPSALANVIQGGDLVLTQGAGDVGRVAKQLESLQLDINKMQNA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLTC_STRPM
Sequence: MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVELESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_CAMJ8
Sequence: MNLTPKEIVKFLDDYVIGQKKAKKIIAIALRNRYRRMQLSPELQDDIVPKNILMIGSTGVGKTEIARRLAKMMGFPFIKIEASKYTEVGFVGRDVESMVRDLANAALNLVKNEQREKNKDKIDEFIENKILEKLLPPLPKGISDEKQEEYKNSLEKMRTKLRNGDLDESTIEIEISQNMFDTNPNLPPEMGAMQDIVKVIGVGSKKVKKEMKIKDAKNALKNEAGEKILDQESIKSEALKRAENEGIIFIDEIDKIAVSSGNSNRQDPSKEGVQRDLLPIVEGSNIQTKIGTLKTDHILFIAAGAFHLSKPSDLIPELQGRFPLRVELDSLDDKALYEILTRPKNSLLKQYSQLLKTENLELEFDDEAIKEIAKIASRANEEMQDIGARRLHTVIEKLLEDLSFEADEYAGKKFVVDKKMVEEKLGDIIENKDLARYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_RABVA
Sequence: MDADKIVFKVNNQVVSLKPEIIVDQYEYKYPAIKDLKKPCITLGKAPDLNKAYKSVLSGMNAAKLDPDDVCSYLAAAMQFFEGTCPEDWTSYGILIARKGDRITPNSLVEIKRTDVEGNWALTGGMELTRDPTVSEHASLVGLLLSLYRLSKISGQNTGNYKTNIADRIEQIFETAPFVKIVEHHTLMTTHKMCANWSTIPNFRFLAGTYDMFFSRIEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREAILYFFHKNFEEEIRRMFEPGQETAVPHSYFIHFRSLGLSGKSPYSSNAVGHVFNLIHFVGCYMGQVRSLNATVIAACAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQEYEAAELTKTDVALADDGTVNSDDEDYFSGETRSPEAVYTRIMMNGGRLKRSHIRRYVSVSSNHQARPNSFAEFLNKTYSNDS
What is the function of this protein?
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RM46_RAT
Sequence: MAAPIGRTLLGVAKGWRQLDRLWAGSSRGLSLEAAPSSSRSPWRLSGALCLQRPPLITKPLTPLQEEMAGLLQQVEVERSLYSDHELRALDEAQRLAKKKADLYDEEQDQDVTLAQDLEDMWEQEFLQFRPGARETEADKKNDRTSLHRKLDRNLILLVREKLGDQDLWMLPQVEWQPGETLRGTAERILATLSENNMEAKFLGNAPCGHYKFKFPKAIRTESDLGVKVFFFKALLLTGDFVQTGKKGRHVWASKEELGDYLQPKYLAQVRRFLLDL
What are the official names of this protein?
39S ribosomal protein L46, mitochondrial, L46mt, MRP-L46.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL46 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IF1_RICPR
Sequence: MSKDDLIQFTGTVLELLPNATFRVKLENDHIIIAHTSGRMRKNRIRILLGDKVTVEMTPYDLTKGRVIHRH
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_GLUOX
Sequence: MAAGSTIDALGQFELHPVLGHLGEALRFSQSPLFMLIAAAVVLVFLYVGMRPAAVVPGRLQAAAEISYDFVHDLAVSTIGENGATFFPFVFAIFFFILAGNYLGLLPFSFTYTSHIAVTFGLAIMVFIISILASIRFQGVGFLKHFLPAGTPVWLAPLLVPIEIISFLSRPVSLSIRLFANMVAGHVLLEVFAGFTIMLAGLGAFGHVLAIAPIAINIALTALELLVGVLQAYVFAILTCIYLREAVAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXH_HAEIN
Sequence: MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQVKDLIKFVSDQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAKSNQDKQAKSQEIMDVNQAFTAEKVQEFGVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase, UDP-diacylglucosamine pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: UXUA1_AGRFC
Sequence: MRHTWRWFGPVDKVTVQDAAQAGAEGIVSALHHITTGDVWPVDEITKRHEAIKAGGLYWDVVESVPVSEDIKTQTGDWKNHIANWQETLRRLSASGIRTVCYNFMPVLDWTRTDLRWETRHGARAMRFDLTDFAAFDIHILKRPDAKADYPDWLLEEAAKRFAEMPDTKIAALGRNIGAGLPGSADGYTLAQLLEKLRSYHGINRGRLQQNLIDFLSEVTPVAEEVGINICAHGDDPPWPLLGLPRILSTEADYAHMLSQVDSRANGVTLCTGSLGARADNDLPFIAGRFADRIHFVHLRNVTRDTDTVPCSFFEDEHLEGGTDMVAVIAALITEEARRRAEGRDDHTIPMRPDHGQEILDDLTRGAQPGYPAIGRLKGLAELRGIERTLSHGRFGLATGKG
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase 1, D-mannonate hydro-lyase 1.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: SYK_PEDPA
Sequence: MGEKQQPSMNDQLRVRREKMQELRDKGIDPFGHRFERTHLAAQLHEKYSDMTKEELDEQGVVATIAGRMISKRGKGKVGFADLKDRSGKMQLYVRKDVLGEDVYKVFKRSDIGDFLGVTGDVMKTDMGELTIKVTGLTFLSKALRPLPDKFHGLQNVEQIYRQRYLDLIANDDSMDRFRKRTKIVSAVRRYLDGNDFAEVETPVLHTQAGGASARPFITHHNALDINLYLRIALELHLKRLIVGGMERVYEIGRVFRNEGIDTRHNPEFTMLETYAAYFDFHDVMDETEGIFKAAVAAVSDDGKITYQGTELDLGQDFERLHMVDAIKKYAGVDFWPKMSVEDAKKLADENGIHYESWWTVGHIINEFFEEKVQDQLKQPVFIYGHPVEISPLAKKNAEDDRFTDRFELYILGNEYGNAFTELNDPIDQRARFEAQVAEREAGNDEAEGIDEDYIEALEYGMPPTGGLGIGIDRLVMLLTDAPSIRDVLLFPTMKPID
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_MALP2
Sequence: MKNLILKEILNNELKRQQGYIELIASENYVSEQILEATGSVFTNKYCEGYPNRRYYGGCEYADQIEQLAIDKAKEIFNAKFANVQPHSGTQANVAAYLSVLKPNDKILAMGLNEGGHLSHGSKVNISGKTYEADHYGVDKETQCLDYDAILKQAQEVKPKLIVCGASNYSRVVDFKKFGEIAKSVGAYLLADVAHISGLIVAGYHPNPLPYADIVTTTTHKTLRGPRSGLILTNNEELIKKINSAVFPGSQGGPLMHVIAAKYLCFDEASKPEFKTYIKNVIDNIAILSQTLKELGYKIIADGSDNHLLSVDLYSSKQITGDLVEQWLEQAKIVVNKNLIPYDINSAKSPSGIRIGSAAMTTRGFTTKEFKQIGLWIHEIIESKGNPNTINKIRNEVDLLVKKFPIYQDIKY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.