PharMolix/UniProtQA huggingface dataset:
Protein: SMS_MACFA
Sequence: MLSCRLQCALAALSIVLALGCVTGAPSDPRLRQFLQKSLAAAAGKQELAKYFLAELLSEPNQTENDALEPEDLSQAAEQDEMRLELQRSANSNPAMAPRERKAGCKNFFWKTFTSC
What is the function of this protein?
May enhance low-glucose-induced glucagon release by pancreatic alpha cells.  This effect may be mediated by binding to GPR107 and PKA activation (By similarity).  May regulate cardiac contractile function (By similarity).  May compromise cardiomyocyte viability.  In the central nervous system, may impair memory retention and may affect hippocampal excitability.  May also have anxiolytic and anorexigenic effects.  May play a role in arterial pressure regulation (By similarity).  May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH.  Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (By similarity).
What are the official names of this protein?
Somatostatin.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RCF1_VANPO
Sequence: MSRIPSSFDYKDNVKDVSEMDFMEKLVFRAKQQPLVPIGCLLTTGAIVLAAQSVRSGNKNKAQVFFRWRVGLQAATLVALLAGSYIYSSNKAERKTEEQLLKEKAKMREQLWIQELERREQETEARRKKAEMFRLKAKENEEASKNLEQELKALESKVNASK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: AGO2_XENTR
Sequence: MYAGAGPVLVPPTPTPPLPMPAYTFKPPPRPDFGTSGRTIKLQANFFEMDIPKIEIYHYEIDIKPEKCPRRVNREIVEHMVQHFKAQIFGDRKPVFDGRKNLYTAMPLPIARDKQVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRVWEEPNAPLNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLSAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA
What is the function of this protein?
Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC).  The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA).  These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing.  The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target.  Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2.  Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity.  The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
What are the official names of this protein?
Protein argonaute-2, Argonaute2, Argonaute RISC catalytic component 2, Eukaryotic translation initiation factor 2C 2, eIF-2C 2, eIF2C 2, Protein slicer.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: EDN2_RABIT
Sequence: MVSVPTAWCSVALALLVALHEGKDQAAATLEQPASSPRARAAHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPGQTAPYGLGNPPRRRRRSLPGRCECSSARDPACATFCHQRSRADAVGVPGSQSSADAFQAGKTWATPGELLRTLRDISAAKTHFAKRQQEATREPRTTHSRHRKR
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides.
What are the official names of this protein?
Endothelin-2, ET-2, Preproendothelin-2, PPET2.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAA_LISMO
Sequence: MQLLKDKFGRVHDYIRISVTDRCNLRCVYCMPEEGLTFLPHEKVLSKDEIVSFMELMVKFGIKKVRITGGEPLLRTDIVEIVRGLGAIPEIEDISITTNAMYLAKKAEALKEAGLTRVNISLDSLHADRFKAITRGGRLQKVLDGIQKAEEVGLFPIKLNVVLIKGQNDDEITDFLRFTKDKDINIRFIEYMPIGHAGTSWKEKYLPLDTIFEACNEAGYEYEPVDSIRGNGPSENFRIKGAKGTFGVIHPVSAHFCDSCNRLRLTADGYIKACLYWDEEMNIRPFIQDPVKLMQLVQKAIDNKPENHEMALKLQDEVQSNKPTWRRMSQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: PLA4_ORYSJ
Sequence: MSTTAPRAVAERWRELHGEDHWKGLLDPLDADLRRSVIGYGELAQATNDAFIREAWSPHAGACRYSRDRFLEKAQASTQLAGLYEVTAFFYATAGAGGVPAPFMVRNRESNWMGYVAVATDAGVAALGRRDVVVAWRGTVRPMEWLNDLDFTLVSAAGVLGAGGRSPAPRVHRGWLSIYTASDPASKYSKLSAREQISDEIKRLMDKYKDEETSITVVGHSLGAAVATLNAADIVSNGLNQHGACPVTAVAFACPRVGDSGFRKLFDELPGLRLLRVCNSPDVVPKYPPMGYADVGVELPVDTRRSPYLKSPGNQAVWHSLECYMHGVAGAQGKRGGFKLEVDRDVALVNKNVDALKEEYHVPPSWSVQRDKGMVRGADGHWKLMDYEGEESSQDK
What is the function of this protein?
Acylhydrolase that catalyzes the hydrolysis of phospholipids at the sn-1 position.
What are the official names of this protein?
Phospholipase A1-II 4.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_BORA1
Sequence: MVTTNAPSLRIAVLGAGSWGTALAAAASRRHPTLLWARGAAQAASLSIERENTRYLPGVALPAALRFSADLDQALDFLGTDPDQALIILGVPVAGMSSIMAELALRLPLRGMIRTPIVWTCKGFETDSARLPHEIVHASVGELAGMACGVLSGPSFAREVAQGLPVALTVASRHERVIRAVTAALHGAAVRVYASQDVPGVEMGGALKNVIAVACGISDGLALGTNARAALITRGLAEMTRFGLALGARADTFAGLTGLGDLVLTATGELSRNRRVGLEIGAGRKLDDILASGVTAEGVRCARAALARAHSLGVELPITEAVCAVLFEGVAPMTAVSALLAREARQEGSTDVQP
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NARF_HUMAN
Sequence: MKCEHCTRKECSKKTKTDDQENVSADAPSPAQENGEKGEFHKLADAKIFLSDCLACDSCMTAEEGVQLSQQNAKDFFRVLNLNKKCDTSKHKVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKSLGVHYVFDTTIAADFSILESQKEFVRRYRQHSEEERTLPMLTSACPGWVRYAERVLGRPITAHLCTAKSPQQVMGSLVKDYFARQQNLSPEKIFHVIVAPCYDKKLEALQESLPPALHGSRGADCVLTSGEIAQIMEQGDLSVRDAAVDTLFGDLKEDKVTRHDGASSDGHLAHIFRHAAKELFNEDVEEVTYRALRNKDFQEVTLEKNGEVVLRFAAAYGFRNIQNMILKLKKGKFPFHFVEVLACAGGCLNGRGQAQTPDGHADKALLRQMEGIYADIPVRRPESSAHVQELYQEWLEGINSPKAREVLHTTYQSQERGTHSLDIKW
What are the official names of this protein?
Nuclear prelamin A recognition factor, Iron-only hydrogenase-like protein 2, IOP2.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_JANMA
Sequence: MDLIQQLEQEEIARLAKNIPDFAPGDTVVVNVNVVEGTRKRAQAYEGVVISRRNRGLNSNFIVRKISSGEGVERTFQLYSPLIASIEVKRRGDVRRAKLYYLRERSGKSARIKEKLPQRRVAAKQAAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RS8_PHYMT
Sequence: MVMTDNIADMLTRIRNANQMHHLQVVVPISKLKVEILKVLKEEGFIKNFFIKEFKREIIISLKYTIERERVIKGLKKISKPGLKVYTSVEKIPKVLSGLGIALISTNKGILTDNKARLEKVGGEVLAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: 041L_IIV6
Sequence: MNFIRENETKYVLSTYQSMTPKNLMEYLLKYNYDNDCVYIFNNLPKDLQKEVDDLAKEVVKANDEQIKAQDEQIKANDQKLKQLDVMIEFMKQYNKQLDNDIYLLEHQLENKRELNRQLGIF
What are the official names of this protein?
Uncharacterized protein 041L.
Protein: VPU_HV1H3
Sequence: MQPIQIAIVALVVAIIIAIVVWSIVIIEYRKILRQRKIDRLIDRLIERAEDSGNESEGEISALVEMGVEMGHHAPWDVDDL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: Y940_TREPA
Sequence: MFFEKKRESRVQPMHIQAGCATIAGTRGDRGGYGACFPAPGCPDTL
What are the official names of this protein?
Uncharacterized protein TP_0940.
Protein: NUDC_SALNS
Sequence: MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: RNN1_NEUCR
Sequence: MVQLLSAFVSLLSVVAVSGAAIPAPAPEAVVDVAPETATIEPTGNFTAQACMYICGSVCYSSSAISAALNKGYSYYEDGATAGSSSYPHRYNNYEGFDFPTAKPWYEFPILSSGRVYTGGSPGADRVIFDSHGNLDMLITHNGASGNNFVACN
What are the official names of this protein?
Guanyl-specific ribonuclease N1, RNase N1.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease N1/T1 family.
Protein: MSCL_VIBC3
Sequence: MSLLKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSFVLLAAQGDAPAVVIAYGKFIQTVVDFTIIAFAIFMGLKAINSLKRKEEEAPKAPPAPTKDQELLSEIRDLLKAQQDK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLMPB_XENLA
Sequence: MSCTRGWRLILLGLLCVGLLGTRGQDESRKVSVQYNPGSSDTSVNVVHVRAVGDGNTIHYVWSTLGTPTVLLIYTHSETSQLQVNWTKLLSPAPQGALRVEPEESVSYATALLFTRIFEYQDVNNTANFSGTDEKYFYPPYNLSEFLWENANATVNATSLSANLTGSNTTDPSGSFHNGSVSFRISAYNTSGRDSSPPRLRHTANCTKLEFLVSGVRPRGNNSRFALEMVTIEKEGRRKMKSVLSIDDEYTPTIFEMMQLVAVAPNSSHARGFLQWKSVAYGSPSGSRADLLPCQLYPLQPLNATFTATSIAHAYFGDDLADAYNLEAFNISFGIADGDFYDKHEFLSWSALIGYGDPPRDSFSILVICIMAVALGTPLLLLIIGTVLVTAVRHKVYPNYQPIN
What is the function of this protein?
Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.
What are the official names of this protein?
Glycosylated lysosomal membrane protein B, Lysosomal protein NCU-G1-B.
What is the protein family that this protein belongs to?
Belongs to the GLMP family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass type I membrane protein; Lumenal side.
Protein: ARNA_ECOK1
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPRGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKSASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLNWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: HTPG_BORBR
Sequence: MSQTTTNSASETLGFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDACDKLRFEAIDQPGLLDGDGELAIRVDYDKAARTITISDNGIGLSRDEAVANLGTIARSGTREFFSQLTGDKQKDAQLIGQFGVGFYSSFIVADKVTVLSRRAGLAANEAIRWESDGQGEFSIAPAEKAGRGTDVVLHLRADEDELLNGWKLREILRRYSDHISLPIRMAKEDWDAEKGEQVKGDELETVNQANALWTRNKSDITDEQYREFYKTVSHDYDDPLAWTHNRVEGRSEYTQLLYVPKHAPFDLWDRDARRGVKLYVKRVFIMDDAEQLLPSYLRFVRGVIDSADLPLNVSREILQESRDVRAIREGSAKRVLSLLEDMAENKAEDYATFWTEFGQVLKEGTGEDAANRERIARLLRFASTHDGEQAQTVSFADYVGRMKDGQDKIYYVTADTFTAAANSPHLEIFRKKGIEVLLLSDRVDEWMLSYLREFDGKSLVSVAKGGLDLAELADEEEKKRQSEVAETFKPLVERLQQALAEQVKEVRVTQRLVDSPACVVVGQNELSPHLLRMLKAAGQEAPEVKPVLEINPDHALIARIRDASDAEFGDWAALLLDQALLAEGAQIADPAAFVKRLNGLLLKA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFH_LEPBY
Sequence: MSDENIRQIAFYGKGGIGKSTTSQNTIAALAEMGERIMIVGCDPKADSTRLMLHSKAQTTILHLAAERGAVEDLELEEVLLTGYRDVKCVESGGPEPGVGCAGRGIITAINFLEENGAYEDLDFVSYDVLGDVVCGGFAMPIREGKAQEIYIVTSGEMMAMYAANNIARGILKYAHSGGVRLGGLICNSRKVDREIELIETLAQRLNTQMIHFVPRDNIVQHAELRRMTVNEYAPDSAQAQEYATLARKIKDNTNLTIPTPISMDELEDLLVEFGLLGGDEEYEKAIKQDLAKRGA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RL2_RIPO1
Sequence: MGIRSYRPYTPGTREASVSDFAEITKTEPEKSLTTYKHSRQGRNNRGVITSRHRGGGHKRLYRIVDFRRDKHNIPAKVAAIEYDPNRNARIALLFYKDGEKRYILAPAGITVGTMVVSGENAPFEVGNALPLARIPLGTDVHNIELTPGKGGQMVRAAGGSAQVVAKEGDYVTLRLPSKEVRMVRKECYATIGRVGNVEDRNIKLGKAGRTRHLGQRPHVRGSVMNPVDHPHGGGEGRAPIGRSGPVTPWGKPALGAKTRNKKKQSSKLIVRRRTR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HBB_CHENI
Sequence: MVHWTPEEKQYITSLWAKVNVEEVGGEALARLLIVYPWTQRFFSSFGNLSSASAILHNAKVLAHGKKVLTSFGDAVKNLDNIKKTFAQLSELHCEKLHVDPENFKLLGNILIIVLATRFPKEFTPASQAAWTKLVNAVAHALALGYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TRMD_SALPK
Sequence: MFIGIVSLFPEMFRAITDYGVTGRAVKKGLLNIQSWSPRDFAHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGVDERVIQAEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVLGHEASAIEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPD2_SCHPO
Sequence: MTVAALNKLSALSGSIQKSFSPKLISVGIIGSGNWGTAIAKICGENAKAHPDIFHPQVHMWMYEEKIQHEGKECNLTEVFNTTHENVKYLKGIKCPSNVFANPDIRDVGSRSDILVWVLPHQFVVRICNQLKGCLKKDAVAISCIKGVSVTKDRVRLFSDIIEENTGMYCGVLSGANIASEVAQEKFCETTIGYLPNSSVNPRYTPKTIQALFNRPYFRVNIVEDVPGVALGGALKNIVAVAAGIIDGLELGDNTKSAVMRIGLLEMQKFGRMFFDCKPLTMSEESCGIADLITTCLGGRNHKCAVAFVKTGKPMHVVEQELLDGQKLQGAATAKEVYEFLDNQNKVSEFPLFTAVYRIVYEGLPPNKLLEAI
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)] 2.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4034_NOSS1
Sequence: MFIDELSPIFKQLVQHPASFLGGFASGVLRLNLADDPVKSWLDKQRGVNSYSFPVTDAHNGKASGPQSISID
What are the official names of this protein?
UPF0426 protein asl4034.
What is the protein family that this protein belongs to?
Belongs to the UPF0426 family.
Protein: YBHG_ECO57
Sequence: MMKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTVNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRAVEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CYSD_PSE14
Sequence: MVDKLTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLARKAFFPGKLPFPVMHVDTRWKFQEMYRFRDKMVEEMGLDLITHINPDGVAQGINPFTHGSAKHTDIMKTEGLKQALDKHGFDAAFGGARRDEEKSRAKERVYSFRDSKHRWDPKNQRPELWNVYNGNVNKGESIRVFPLSNWTELDIWQYIYLEGIPIVPLYFAAERDVIEKNGTLIMIDDERILEHLTDEEKSRIVKKKVRFRTLGCYPLTGAVESEATSLTDIIQEMLLTRTSERQGRVIDHDGAGSMEEKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: MPRF_STAAC
Sequence: MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKMDISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILDKITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALSGLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTSFLMSYQKDIIAKIPSLSLAILVFFTSMIFFVNNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK
What is the function of this protein?
Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge.  LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Phosphatidylglycerol lysyltransferase, Lysylphosphatidylglycerol synthase, LPG synthase, Multiple peptide resistance factor.
What is the protein family that this protein belongs to?
Belongs to the LPG synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HCP_ACTP2
Sequence: MYCVQCEQTMVTPMGNGCSFGQGMCGKTAETSDLQDLLIACLHSLSAWALKAREHGIINHDADNFAPRAFFATLTNVNFDSNRIVGYAQQAIIYRNELIKAISEVEPNPELNHPLAHIELKGISIDQLAEQAKEFALDTDRAEIGEEVHGVRLLALYGLKGAAAYLEHAYVLGKFDNDLYVEYHGFMAWLGTKPSDLNELLEKSLAIGSMNFKVMAMLDAGETETFGNPVPATVNIRPVKGKCILISGHDLKDLKELLEQTEGKGINVYTHGEMLPAHGYPELKKYKHLVGNYGSGWQNQQKEFARFPGAIVMTSNCLIDPNVGDYADRIFTCNIVGWPGVVHLEKHNFAPVIEKALECDGFPYTELEHYITVGFGRKTLIDASDAVIDLVKAGKLSHVFVIGGCDGDKEERHYYTDLAYALPKDTAVLTLGCGKYRFNKLDFGTIDGGLPRLLDAGQCNDTYSAIMLAVTLSQKLGIGLNELPLSIVLSWFEQKAIIVLLTLLALGVKNVYSGPSKPAFLNDNVMNLLHEKFGLSGLTTPEQDFGHIINK
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.