PharMolix/UniProtQA huggingface dataset:
Protein: NGF_XIPMA
Sequence: MRSSMLVLFLIFSAQAVAPIIGVLCSVTTAQQDHPTSIPTVDPKLFNKRRHLSPRVLFSSQPPDAEPAGGQGVSRRTRRQPQHRGVYSVCESVSVWVGNKTKATDISGKEVTVLPYVNINNVKKKQYFFETTCHSPPSGGSRCLGIDARHWNSHCTNSHTFVRALTSSENQVAWRLIRINVACVCVLSRKSWQH
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.
What are the official names of this protein?
Nerve growth factor, NGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBA2_SYNSC
Sequence: MSTAIRSGRQSNWEAFCQWVTDTNNRIYVGWFGVLMIPCLLAATICFTIAFIAAPPVDIDGIREPVAGSLIYGNNIISGAVIPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVCFHFLIGISAYMGRQWELSYRLGMRPWICVAYSAPLSAAMAVFLVYPFGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTEAESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGAWPVVGIWFTSMGISTMAFNLNGFNFNQSILDSQGRVLNTWADVLNRANLGMEVQHERNAHNFPLDLAAAESTPVALQAPAIG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 2, PSII D1 protein 2, Photosystem II Q(B) protein 2.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RS6_ECOHS
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TRPA_DESVV
Sequence: MSASRLERRIREAQAAGRPALIPFLTAGFPTPERFWDELEALDAAGADIIEVGVPFSDPVADGPVVAAASQRALESGVTLRWIMDGLAARKARLRAGLVLMGYLNPFMQYGFERFVTDAADAGVAGCIIPDLPLDEDADLRALLAARGMDLIALVGPNTGEGRMREYAAVASGYVYVVSVMGTTGVRDGLPVEVADTLARARQCFSIPVALGFGISRPAQLEGLSHPPDAVIFGSALLRHLDAGGDAASFMKAWAER
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: AHPC_MYCTU
Sequence: MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPGKWRVVFFWPKDFTFVCPTEIAAFSKLNDEFEDRDAQILGVSIDSEFAHFQWRAQHNDLKTLPFPMLSDIKRELSQAAGVLNADGVADRVTFIVDPNNEIQFVSATAGSVGRNVDEVLRVLDALQSDELCACNWRKGDPTLDAGELLKASA
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.  Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system.  Does not however seem to play a role in detoxification of isoniazid.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, MtAhpC, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTUD_CITK8
Sequence: MISLMQLQDVAETTRLGPLSGDVKPGEILHLVGPNGAGKSTLLARMAGLTFGEGTVIFDGASLETWPAAKLAQHRAYLAQQQNPPFSMPVWHFLTLHQPDKTQTNLLNDVAQALGLSDKLGRSANQLSGGEWQRVRLAAVILQIHPHANPHGQLLLLDEPMNSLDVAQQNALDRLLSQLCSQGIAIVMSSHDLNHTLRHAHRAWLLKQGKLIASGRRDEVLTPPNLAQAYGMNFRRLDVEGHRMLISTT
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MOAA_MOOTA
Sequence: MQDTFQRQINYLRIAITDRCNLRCRYCMPATGVPLKGHEDILRLEEIATLARVAAGTGISRIRLTGGEPLVRKNVVTLVRELAAIPGLEEISLTTNGIFLGALAFSLKEAGLKRVNISLDTLKKDRYRYITRRGNITSVWQGIRAALAAGLTPVKLNVVITRGFNDDEILDFARLAREEPLHIRFIELMPIGTAAASGTAYVPAEEIKGRISRVYPLEPFPDLATNGPAANFRLVGGRGSVGFITPMSNHFCSRCNRLRLTADGKLRPCLYWDGEIDIKGPLRAGAPETELAAIFARAVSLKPAEHHMENGWRQPRAMSQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RAD17_ASHGO
Sequence: MLESTALFSATTIHLDRLMCAFNCMTPFGQRDDVLITIDRDGLTFIRQNNHAAEIQLFLAKELFQYYSIREGFEGEIQLCMKLNHLLDTVSVANRDKDDVVECTLSYDGEGTPFMLILEDSMITEQVEYATYLVGEMDRTGLELDRARLEFECILKGDVLYSALRDLREIGCKECYLYIVTSSRARPMFALVSRGQLGLSKIILPSERSVLEKLEVYENDSTTLIHDAPVIGLFDFAALDKLRPSTKIASKVLIRKDVHGLLAVNILSDTNAILVPEKRELIRASRSVSAEYPTVVIEVFLLEKASVGDIDVRDVHQLMLTSPAHRRSGFADSGSRIVSVTPTATSAAHTGAGSLLGLAPPSAFPAEETQDPDESYHPAPSNTDIPLFL
What is the function of this protein?
Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.
What are the official names of this protein?
DNA damage checkpoint control protein RAD17.
What is the protein family that this protein belongs to?
Belongs to the rad1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14Z_MYCSK
Sequence: MAKKALVNKANKKPKFKVRGYTRCQRCGRPHAVFRKFGLCRICLREMAHAGELPGVQKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RNH2_SHEPA
Sequence: MAVIKGITPEQIAQICVGQYAGVDEVGRGPLIGNVVTAAVILDPNNPIEGLNDSKKLSEKKRELLFEQIQQKALSVSVGSATPAEIDELNILHATMLAMQRAVAGLNIKPSSVLVDGNRTPDFGVESHAIIKGDGLIDAISAASIIAKVVRDREMDALALLYPEYGFEKHKGYPTKAHFEALAQHGVLPEHRKSFRPVREALA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S38AA_PONAB
Sequence: MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLWVGLGILVVSTVTTLSVSEDVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAQEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDQEVPEENKPPSRHAGRKAPGVQGQMAPPLPDSEREKREPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLEPGDGGLHPRPQAVLSEQQNGLAVDEGEKAEGVPPPGNAAGDTGQPAEDSDHGGKPPLPEEKPAPGAGLPPEPREQRDVERAGGDQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHPEPGAAVPRGQEAPEGKARETMENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHPERPVGRDPAGPPDGGPDTEPRAAQAKPRDGQKDAAPGAAGTVKELLKGLEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGGSQDRKKPGKEVAATGTGILKEANWLVAGPGAEMGDPHMKPKQMSRDLGLAVDLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDHGGYLEMRKEARGGDHMPVSHEQLGGEEDAAVPEPRQRPEPELGLKQAVPGGQRPDNAKPNRDLKLQAGSDLRRRRRDLGPHAEGELAPRDRVIIGLNPLPDVQVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGAPEES
What is the function of this protein?
Putative sodium-dependent amino acid/proton antiporter.
What are the official names of this protein?
Putative sodium-coupled neutral amino acid transporter 10, Solute carrier family 38 member 10.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: A51_LOXIN
Sequence: MLCFFVLFFCCGTVLLEGADIDEIEHADKRRPIWNMGHMVNAVYQIDEFVDLGANAIETDVTFTKSANAEYTYHGVPCDCHRWCKKWEYVNDFLKALRRATTPGDAKYRSQLILVVFDLKTDYLTASTAYDAGKDFAKRLLQHYWNGGSNGGRAYIILSIPDLAHYKFINGFKEQLKTQGHEDLLAKVGYDFWGNEDLSSTRAAFQKAGVQDKEHIWQSDGITNCWLRTLKRVREAVANRDSSNGYINKVYYWTVDKYASVRDAINAGADGIMTNYPNVIVDVLKENDFKGKFRMATYNDNPWETFK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) with high activity (PubMed:18082635).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, massive inflammatory response, platelet aggregation, increased vascular permeability, and causes edema and death in mice (PubMed:18082635).
What are the official names of this protein?
Dermonecrotic toxin LiSicTox-alphaV1, Dermonecrotic toxin 6, DT6, LiRecDT6, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 6, SMD 6, SMase D 6, Sphingomyelinase D 6.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NFI_YERE8
Sequence: MVDTKALRAEQLQRASEISLQDDIASESVRFIAGADVGFEQQGEVTRAAIAVLRYPSLELVEYQVARVATSLPYIPGLLSFREYPALLAAWAQIQQRPQLVFVDGQGIAHPRRLGVASHFGLLVDVPTIGVAKSRLCGNFEPLGDDNGALQPLVDADEQLGWVWRSKSRCNPLFISPGHRVSVGSALEWVQHCIAGYRLPEPTRWADAIASNRPQFQRWVRKSPDLLGKHRDMI
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_PROM2
Sequence: MFTIALPKGALLRDSISTFKRAGLDFSNALDENNRSLTFESNCKRAKALLVRNGDVPVYVSYGQADLGIVGYDVLRESELKVAKLLDLGFGGCHMSLAVKKNSNYSKPTDLPANCKVASKFIKTARSYFEELNIPVEIVHLTGSVELGPITGMAEAIVDLVATGKTLKENGLIKIDDLFYSTARLIGNPLSMRLDDNHLRDTILSIESTNSLIEE
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_METAC
Sequence: MNVQLILRSLTYKEEQRVIIRPIGERVLLKHQKKEEVTKGGIYIPESARQEKKEGIVIAVGTFEDGKELPLKKGDHVIYGGYQADEIEIDDEKYIFVDFKDILATVVEE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDM_ECO57
Sequence: MFTYYQAENSTAEPALVNAIEQGLRAEHGVVTEDDILMELTKWVEASDNDILSDIYQQTINYVVSGQHPTL
What are the official names of this protein?
Protein bdm homolog.
Protein: ISPG_NEIG1
Sequence: MNTLQRRKTHQVLIDHITVGSEAPVVIQSMTNTDTADAKATALQIKELSDAGSEMVRITVNSPEAASKVAEIRRRLDDMGYATPLIGDFHFNGERLLAEFPECGKALSKYRINPGNVGKGVKGDEKFAFMIRTAAENDKAVRIGVNWGSLDQSLAKRMMDANLVSSAPKPPEEVMKEALIVSALESAEKAVLLGLPEDKIILSCKVSAVHDLIQVYRELGSRCVYPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGSPRTQEVVVGQEILQTMGLRSFTPMVTACPGCGRTTSTVFQELAQDVQNYLRQKMSIWRTLYPGVESLNVAVMGCVVNGPGESKLADIGISLPGTGETPVAPVYVDGERKVTLKGNNIASEFLAIVEEYVKTNYGKNSSKRNKGKVIPIQSL
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: HSLU_XANOR
Sequence: MPNPDTSTMTPREIVQELDRHIVGQHDAKRAVAIALRNRWRRMQLPEELRNEVMPKNILMIGPTGVGKTEIARRLATLANAPFVKVEATRFTEVGYVGKDVEQIIRDLADTSVKLYREQAKVRVRNQAEERAEDCILDALLPRRATGIGFDPEAARNEPSSQENDTRIKFRRMLRNGELDEREIELEVAVNASMDIMTPPGMEEMGQQLRQMFSNLGSGKSQKRKLTIKAARPLLIEEEAGKLVNEDDVRTAAIKACEQHGIVFIDEIDKVAKRGEAGSNGGDVSREGVQRDLLPLVEGSNVSTKYGTVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELTALTKADFVRILTEPKAALIKQYEALLQTEGVSLTFAQDAVDRLAEIAAQVNERQENIGARRLHTVLERLLDVLSYEAPDRDGQSVTVDAAYVDAQLGELVQDPDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1496_BRADU
Sequence: MDKDRIVGSAKEFAGRAEGAVGDLAGDAQTQASGKAREAAGTVQNLYGQAKDAVREASETAAGYAKDAYDNSGETFRDGSQAIARKVQDNPLGALLVAGGIGFALALLMSRPARRPPPRWRYYG
What are the official names of this protein?
UPF0337 protein blr1496.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: RL4_ALKEH
Sequence: MELQLRNAQGQTDGSVQVADAAFGDRFREALIHQVVVAYLAGARAGTRAQKTRAEVRGGGAKPWRQKGTGRARAGTIRSPIWVGGGRAFAARPQDHGQKVNKKMYRGALRSIFSELARQERLVVVESIGVDEPKTAKLAAQLEQLGVERPLIVADEVDQNLYLAARNLPGVDVRDVPGLDPVALVGAEQVVITVQALRQVEEWLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RSMA_MYCLB
Sequence: MQRKSGCTLTIRLLERTEIRWLVKELECRPRKSLGQNFVHDANTVRRVVSTSRVNRSDFVLEVGPGFGSLTLALLDCGAAVSAIEIDPVLAGRLPQTVAEHSNNEIHRLTVCNRDVLSFRRGDLATEPTALVANLPYNVAVPALLHLLAEFPSIRTVTVMVQAEVAERLAAEPGGKDYGVPSVKLSFFGRVRRCGMVSPTVFWPIPRVYSGLVRVDRYATSPWPTDDAFRRQVFELVDIAFTQRRKTSRNAFVKWAGSSNESANRLLAASIDPARRGETLSIDDFVRLLRRSDGRDDAAVRSASAS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCYP_ALKCK
Sequence: MDLFLTLLIIAIVLAVAGLLFYMQKKHVSFSIRVLLALGAGVVYGLLLQFFFAPDSSVIQQSMDWVNILGTGYVRFLQMIVMPLIFISILSAFTRMTLTKNLGKISALILGTLIATTAIAAAIGITASSVFQLEAIDIPAGEAELSHGDALEESYAGMEAATLPQQIVELIPANPFLDLTGERPTSAIGVVIFSAFLGVAYLGVRRKQPEAADTFKGIVNALYAIIMRVVTLILRLTPYGVLAIMTRTVATSDLQAISTLGTFVLASYAALIVMFVIHLIILAATGLSPITYVKKAFPVLAFAFTSRTSAGALPMNIQTQKKLGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAVMIAPTVGQNPLEPTFILLLIVVIAISSFGVAGVGGGATFAAILVLSALDFPIALAGLLISIEPLIDMGRTALNVSGSMVSGIFTSKVTGSLDKEVFSDPNEQLDTQDMQG
What is the function of this protein?
Mediates uptake of L-cystine, the oxidized form of L-cysteine.
What are the official names of this protein?
L-cystine uptake protein TcyP, Transporter of cystine TcyP.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARGR_ECOLI
Sequence: MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL
What is the function of this protein?
Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon.  Predominantly interacts with A/T residues in ARG boxes.  It also binds to a specific site in cer locus.  Thus it is essential for cer-mediated site-specific recombination in ColE1.  It is necessary for monomerization of the plasmid ColE1.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_ECO57
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PHNN_SALAR
Sequence: MGKLIWLMGPSGSGKDSLLAELRQQEHEQLLIAHRYITRAANAGNENHIALSQQEFFIRAKQNLLALSWYANGFYYGLGIEIDLWLHAGFDVVVNGSRAHLSQAQARYGTSLLPVCLTVSPDILRQRLQTRGRENDAEIAARLERAAHYPPFNCHTVNNDGSLLQSVERLLILMGRKEEHYASL
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: PNP_STRPB
Sequence: MQGNPLVVEVGQVAKQANGATVVRYGDSTVLTAAVMSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFIINPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQEQIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVKAEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVVDFLPKVHGSGLFTRGQTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGETGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITALQMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVDKIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKVGEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKIDEKGRVDASMKALIPRPPKPEKKEEKHD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_ECO7I
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVLMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVAGDPSPDGQGTLQIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPX1_SCHPO
Sequence: MKLGRFLENGREQIRNLLLNASTVSSAPSFSFVSGNESADLDSCASSIVYAYCLQRKQLGRIVVPFFNIPRKELRLRPELSYLLNLASISSDDIVFLDDIVKLPKRIFSNPIYLVDHNSLDRKDLENFNGSIAGIIDHHKDEGGSLHADPRIIEECGSCCTLVCRYFMPVIRSLYDSKVSELHQTATNLAVLALGPILIDTGNLKNEKTTDTDVKIVNDLCSFVPKDWVRDEFFDTLKEKKKSCKGFSFDDLLRRDLKQYFPDGIVVNYASVGKGLDWIKKKRLGWEDELKSFAEVQNSDLVIVGLSLSKNDEFGRQLILYKRTERGAGLADSFLKLSKQNLGLEIIEEKDNGDLSMWNQRNSAASRKKVVPLLMDSVKQVASK
What is the function of this protein?
Degradation of inorganic polyphosphates.
What are the official names of this protein?
Putative exopolyphosphatase, ExopolyPase, Metaphosphatase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
Protein: YOZD_BACSU
Sequence: MKEIDLVIDTEEIAEFFYRELARRGYIPSEDELFEIADITFDYLIEKCMIDEELDEDE
What are the official names of this protein?
Uncharacterized protein YozD.
Protein: SMG_ECO45
Sequence: MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNALLWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLETREMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.