PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_LACLM
Sequence: MVDVNKFESMRIGIASPQKIRYWSFGEVKKPETINYRTQKPEREGLFDERIFGPQKDWECACGKLKGVFYKNQVCELCGVQVTTAKSRRERMGHIELAAPISHIWYFKGIPSRMGLALDMSPRALEEVIYFASYVVIDPKETDLEKKQLLTEREYREQLLKNGFGSFVAKMGAEAIQDLLNDVDIDKEVAELKEELKTVTGQRRVKIIRRLDVLSAFRKSGNALSWMVLNVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLMELNAPNIIVQNEKRMLQEAVDTLIDNGRRGRPITGAGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMAQLVKKELAANIRAAKRKVERQDSDVWDVLETVVKEHPVLLNRAPTLHRLGIQAFEPVLIDGKAIRLHPLACEAYNADFDGDQMAIHLPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEKGREGEGMIFATPEEVEIAMRNGYVHLHTRIGIATKSLNKPWTENQQDKILVTTVGKVIFNSIIPEGMPYLNEPTDVNLTTSTDDRFFMDAGQNIKEVLAGIDTVRPFKKGYLGNIIAEVFKRYRTTATSEYLDRLKDLGYHQSTLAGLTVGIADIPVVEDKHEIIDAAHKRVEQITKQFRRGLITDDERYNAVTGVWRDAKESLEKRLIEEQDLTNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGKIMELPIISNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLVIADIATGKEMVEPLFERLVGRYTRKSVLHPETGEMIIGDDTLISEDIARKIIEADVKEVTIRSVFTCKTPHGVCKHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASSSDITQGLPRVQEIFEARNPKGEAIITEVTGTVESIVEDGATRTREITVKGKTDTRSYTVGMADVLMVEEGEFIHRGAPLIQGSIEPKHLLQVRDALSVETYLLGEVQKTYRSQGVEIGDKHIEVMIRQMLRKVRIMDNGSTDVLPGTLMDISDFEALNETALLNGEMPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKEDHLLGLKENVIIGKIIPAGTGMFRYRNIEPLADLTNAPEVKEVETETVEN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SAC1_BOVIN
Sequence: MAATTYERLKLHVTPEKFYVEACDDGADDVLIIDRVSTEVTLSVKKDIPPSAVTRPIFGILGTIHLVAGNYLIVITKKKKIGEFFNHVIWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMMNHVLSMDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSRASFVQTRGSIPLYWSQRPNLKYKPLPLINKVANHMDGFQRHFDSQIIIYGKQVIINLVNQKGSEKPLEQAFATMVSSLGNGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDPAGVVLSTQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLIMDGWNSLIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDLKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID
What is the function of this protein?
Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 3-phosphate (PtdIns(3)P) and has low activity towards phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).  Shows a very robust PtdIns(4)P phosphatase activity when it binds PtdIns(4)P in a 'cis' configuration in the cellular environment, with much less activity seen when it binds PtdIns(4)P in 'trans' configuration (By similarity).  PtdIns(4)P phosphatase activity (when it binds PtdIns(4)P in 'trans' configuration) is enhanced in the presence of PLEKHA3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol-3-phosphatase SAC1, Phosphatidylinositol-4-phosphate phosphatase, Suppressor of actin mutations 1-like protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Trafficking between the ER and Golgi is regulated by nutrient status and by TMEM39A. Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS) in the presence of phosphatidylinositol-4,5-bisphosphate.
Protein: VPC25_MYCTU
Sequence: MFLIDVNVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVWASFLRLTTNRRIFEIPSPRADAFAFVEAVNAQPHHLPTSPGPRHLVLLRKLCDEADASGDLIPDAVLGAIAVEHHCAVVSLDRDFARFASVRHIRPPI
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB25.
What are the official names of this protein?
Ribonuclease VapC25, RNase VapC25, Toxin VapC25.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: VMA5A_HUMAN
Sequence: MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQGPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDYSLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELVDSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVDPAIFAF
What is the function of this protein?
May play a role in tumorigenesis as a tumor suppressor.  Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
What are the official names of this protein?
von Willebrand factor A domain-containing protein 5A, Breast cancer suppressor candidate 1, BCSC-1, Loss of heterozygosity 11 chromosomal region 2 gene A protein.
Protein: HFQ_ACTP7
Sequence: MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPARSVSHNNGGTSHTQQAPAVEAVADKAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PHAP_SYNY3
Sequence: MNTQFFEEYQTQLLDWQKKFFSTWMESLPKGTAEIKLTDTFETSLKLQEEMVKSYLEAQEKSATMMIDAQKQFWDNYFQALRQEPVSAN
What is the function of this protein?
A phasin, it attaches to the polyhydroxybutyrate (PHB) granule surface regulating the number and size of PHB granules within a cell.  It probably also acts as a regulator affecting the biosynthetic activity of PHB synthase in vivo.
What are the official names of this protein?
Phasin PhaP, GA13.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distributed in cytoplasm during photoautotrophic growth, insoluble and associated with polyhydroxybutyrate (PHB) granules under nitrogen starvation (PubMed:25911471, PubMed:9683655).
Protein: E131_SOLTU
Sequence: LGVCYGMMGNNLPSHSEVIQLYKSRNIGRLRLYDPNHGALNALRGSNIEVILGLPNVDVKHIASGMEHARWWVQKNVKDFWPDVKIKYIAVGNEISPVTGTSSLTSFQVPALVNIYKAVGEAGLGNDIKVSTSVDMTLIGNSYPPSQGSFRNDVRWFTDPIVGFLRDTRAPLLVNIYPYFSYSGNPGQISLPYALFTAPNAVVQDGSRQYRNLFDAMLDSVYAAMERTGGGSVGIVVSESGWPSAGAFGATQDNAATYLRNLIQHAKEGSPRKPGPIETYIFAMFDENNKNPELEKHFGLFSPNKQPKYNLNFGVSERVWDISAETNSTASSLISEM
What is the function of this protein?
Is thought to be an important plant defense-related product against fungal pathogens.
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase, basic isoform 1, (1->3)-beta-glucan endohydrolase, (1->3)-beta-glucanase, Beta-1,3-endoglucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: YIDC_CERS4
Sequence: MDDQNKNLILATGLSFLVIMVWFFLFPPPEAVTEGEPTVATQQTAVAPSATPDAPTTAVPPDADLPETQRVVIDTPRLQGSISMLGGRLDDLSLKSYHETLDPQSQIVRLLSPVGQPNAYYALYGWTPAGALGYEDVPGANTTWTQVGSGALGVDQPVTLQWDNGKGLVFTRTISVDDHYMFSVAQTVENNSGQAVQLAPYGIVARHGKPLNLQNFFVLHEGVVGRADGKLTETKYDKVAELPQVAREGAQAEVIDAQQDGWIGFTDKYWMTTLIPQQGQPFTSVTKYVPGADIYQAETREQLVTVAPGATAEVSSRLFAGAKEWETIRAYQNEGATEPTEGAEPIPGFIDSIDWGWFFFLTKPIFTVLHWLNHMIGNMGLAIIALTFLLKALVLPLAYKSYVSMARMKELQPELEALRERAGDDKMLMQREMMRLYKEKQVNPAAGCLPILIQIPIFFSLYKVIFVTIELRHAPFFGWLKDLSAPDPSSIFNFFGLAPWAAPTPGTTMALIFIGALPILLGVSMWLQQKLNPAPGDKAQAMIFAWMPWVFMFMLGHFASGLVLYWIVNNLITFTQQYVIMRSHGHHPDIFGNIKASFSRKPAAQPAGKAANDGAAPAKKRKP
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TAL_THEFY
Sequence: MGSPLQQLSDAGVAVWLDDISRQRLRSGNLAELIAQRNVVGVTSNPTIFAKALAEGDAYDGQLRDLAVRGVSVEEAVRLITAYDIRWAADVLRPVYEATDGVDGRVSLEVDPRLARDTERTVAEARALWWLVDRPNLMIKIPATVEGLPAITAALAEGISVNVTLIFSLERYRAVMDAFLAGLEQAQQAGRDLSTIHSVASFFVSRVDTEVDKRLSKIATEEAVALRGKTALANARLAYAAYEEVFSSARWTALAQAGARPQRPLWASTGVKDPELPDTLYVTELVAPGTVNTMPQATLDAVADHGTITGDTVRGHYDAARAHLDAVESVGVSMSDVVETLEDEGVDKFVKSWEELLDRVAQQLAAHT
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_BURCH
Sequence: MKKSARRQSRELATQGLYQWLLSNAPSGEIDAQLRGALGYDKADKELLEAILHGVIREHATLVEALAPSLDRPIDQLSPVERAVLLIATFELTHHVETPYRVIINEAVELAKTFGGSDGYKYVNGVLDKLAAKLRPAETQARRNG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PNP_PHOV8
Sequence: MINPIVKTIELPDGRTITLETGKLAKQADGSVMLRMGNTMLLATVCAAKDAVPGTDFMPLQVEYKEKYSAFGRFPGGFTKREGKASDYEILTCRLVDRALRPLFPDNFHAEVYVNIVLFSADGIDMPDALAGLAASAALAVSDIPFGGPISEVRVARIDGQFVINPTFEQLEKADMDLMVAATYDNIMMVEGEMQEVSEQDLLAAMKAAHEAIKVHCKAQMELMEEVGSTVKREYCHEENDEDLRKAVREACYDKAYAIAASGNRNKHERQDAFDAIRDEFKTQYTEEELEEKGALIDRYYHDVEKEAMRRCILDEGKRLDGRKTTEIRPIWCEVGYLPGPHGSAIFTRGETQSLTSVTLGTKLDEKIVDDVLDQHRERFLLHYNFPPYSTGEAKAQRGVGRREIGHGHLAWRALKGQIPAGYPYTVRVVSDIMESNGSSSMATVCAGTLALMDAGVAMKKPVSGIAMGLIKNAGEEKYAVLSDILGDEDHLGDMDFKVTGTRDGITATQMDIKVDGLSFEILEKALLQAKEGREHILNKLTECIAEPRKDLKPHAPRIETMTIPKEFIGAIIGPGGKIIQGMQEETGATITIEETDGVGRIEIAGTNKKCIDDAMRIIKGIVAVPEVGEVYVGKVRSVMPYGVFVEFLPGKDGLLHISEIDWKRLETIEEAGLKEGDEIEVKLLDIDPKTGKFKLSHKVLLPRPEKQEKK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HACT1_HELAT
Sequence: MDRKFHLCLLLVILGTIIVQGAPLENENDADPDKPQKYRYYLKRATTEKKDNDPAKPGCHYTPFGLICF
What is the function of this protein?
Peptide with unknown function.  Has a limited effect on human peripheral blood mononuclear cells.  Does not show activity against both Gram-positive and Gram-negative bacteria nor is it active on the 26 voltage-gated ion channels tested.
What are the official names of this protein?
Peptide Hact-1.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: GTP1_SCHPO
Sequence: MGVLEKIQEIEAEMRRTQKNKATEYHLGLLKGKLAKLRAQLLEPTSKSGPKGEGFDVLKSGDARVAFIGFPSVGKSTLLSAITKTKSATASYEFTTLTAIPGVLEYDGAEIQMLDLPGIIEGASQGRGGRQAVSAARTADLILMVLDATKAADQREKIEYELEQVGIRLNRQPPNVTLTIKKNGGIKFNHTVPLTHMDYKMAYNILHEYRIHNADILIREDITVDDFIDLVMGNRRYINCLYCYSKIDAVSLEEVDRLARLPKSVVISCNMKLNLDFLKERIWEELNLYRIYTKRKGEMPDFSEALIVRKGSTIEQVCNRIHRTLAEQLKYALVWGTSAKHSPQVVVGLNHRVEEGDVVTIVTK
What are the official names of this protein?
GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
Protein: PYRB_BACFR
Sequence: MENRSLVTIAEHSREKILYMLEMAKQFEKNPNRRLLEGKVVATLFFEPSTRTRLSFETAANRLGARVIGFSDPKATSSSKGETLKDTIMMVSNYADVIVMRHYLEGAARYASEVAPVPIVNAGDGANQHPSQTMLDLYSIYKTQGTLENLNIYLVGDLKYGRTVHSLLMAMRHFNPTFHFIAPEELKMPEEYKIYCKEHNIKYVEHTDFNEEVIKDADILYMTRVQRERFTDLMEYERVKNVYILKAKMLENTRSNLRILHPLPRVNEIAYDVDDSPKAYYFQQAQNGLYARQAILCDVLGITLQDIL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RR18_CUSRE
Sequence: MDKSKRPFIKSKRSFRRRLPPIKSGDRIDYRNISLISRFLSEQGKILSKRVHRFTLKQQRLITLAIKQARILSLLPFTKRKGFERSESTPRTNALKPRNKNKQNNQTQF
What are the official names of this protein?
Plastid 30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid.
Protein: ATOX1_MOUSE
Sequence: MPKHEFSVDMTCEGCAEAVSRVLNKLGGVEFNIDLPNKKVCIDSEHSSDTLLATLNKTGKAVSYLGPK
What is the function of this protein?
Binds and deliver cytosolic copper to the copper ATPase proteins.  May be important in cellular antioxidant defense (By similarity).
What are the official names of this protein?
Copper transport protein ATOX1, Metal transport protein ATX1.
What is the protein family that this protein belongs to?
Belongs to the ATX1 family.
Protein: GTDC1_HUMAN
Sequence: MSILIIEAFYGGSHKQLVDLLQEELGDCVVYTLPAKKWHWRARTSALYFSQTIPISEHYRTLFASSVLNLTELAALRPDLGKLKKILYFHENQLIYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSMGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKTTHLKKMLGLKGNGGAVLSMALPFQPEQRDSEDLLKNFNSECDTHCGLDTARQEYLGNSLRQESDLKKSTSSDNSSSHHGENKQNLTVDPCDILGGVDNQQRLLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDIIRKHLYKGEIAPFSWAALHGKFRSLLTTEPREDL
What are the official names of this protein?
Glycosyltransferase-like domain-containing protein 1, Mannosyltransferase-like protein Xa, Mat-Xa.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: SWC5_YARLI
Sequence: MTNEDLLSDSENDEDFAYKSDKEEDFSDSDDESRKLQRRIDAENKQAMAKEEVKVDKDAMRKIYEEMKSGSGAANEIKPVTVKKPDVTTTQTTQQETASTTPTASTTSTTTSTTSAPAPASIPSSAATNKVKKPKRPKKGSLLDAMNKPKKKLNTLEQSKADWGAFVDKEGIGHDLSQHNKDGYLEKRDFLDTH
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
SWR1-complex protein 5.
What is the protein family that this protein belongs to?
Belongs to the SWC5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GBRE_HUMAN
Sequence: MLSKVLPVLLGILLILQSRVEGPQTESKNEASSRDVVYGPQPQPLENQLLSEETKSTETETGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQTKAHASPKLRHPRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEERPSCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRLDNYSRVVFPVTFFFFNVLYWLVCLNL
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit epsilon, GABA(A) receptor subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRE sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: NRDR_CERS1
Sequence: MRCPFCGNIDTQVKDSRPAEDHVSIRRRRFCPACGGRFTTYERVQLRDLVVIKSSGKREDFDRTKLERSIRIAMQKRPIEPERIDQMISGIVRRLESLGDTDIPSKVIGEIVMESLARIDTVAYVRFASVYKNFQAADDFDKFVSELRPSAPAEE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: KATG_GRABC
Sequence: MKGTPFRSPHLYQEGSSCMHRTIRSVAAVLTVVLSATIPMVPAWSDGEPRSIQFWWPDHLDLSPLRQHAAESDPLGANFNYIKAFQTLDLGAVKKDIAVLLKTPQDWWPADYGNYGPFFIRMAWHGAGTYRTYDGRGGASGAQQRFEPLNSWPDNANLDKARRLLWPIKKKYGEKLSWGDLMVLTGNVALETMGFKTYGFAGGRTDDWEPDLIYWGSGAKFMSNNRDKNGKLEKPLAATQMGLIYVNPEGPNGVPDPVAAARDIREAFGGMAMDDEETVALIAGGHTFGKAHGAASPSKCVGPAPAAAGIEEQGLGWKNKCGTGKGPDAITSGLEGAWSADPVNFTSQYLDNLFGFDWVLTKSPGGAVQWKPKDASADQLVPDAFDASKRHPPMMFTTDIALKTDPSYRKIALSFQKDPEKFKAAFARAWFKLVHRDMGPRSRYFGPEVPKEDLLWQDPLPAITYKAVDEADITDLKQKILASGLTVPELVRTAWGSAASFRGTDKRGGANGARIRLAPEKDWPVNDPQELKKVLDKLESIQTAFNDGNHDGKKISLADLIVLGGNVGVEEAAKKAGYPVTVPFAPGRVDAVQAQTDVKSFAVLEPTADGFRNYYASSNQLSPAEMLVTRASMLNLTVPEMTVLVGGMRVLDANEGHSQLGVLTDHPGVLSNDFFVNLLDMSTKWSKAADTAGVYEGHDRKTDALRWKGSTVDLIFGSNSELRAVAEVYASDDAKEKFVRDFVAAWNKVMTLDRFDLQRQ
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RF1_THEVO
Sequence: MYFMADDEQIRRYEFKRALEELSKLHGRGTELISLYIPPEKQISDVVAYLRDEYSTSSNIKSKSTRKNVLAAIESIMSRLKYYRFPPPNGLVFFVGHIATRGDQTEMYTKIIEPPEPITTFMYKCDSEFHTEMLKAMLDEKEIYGLIVIDRKEATVGFLNGTRIEVVENVQSQVPSKHHQGGQSSRRFERLIEIAANEFFKKVGEIANNAFIPRIKEIRAIFLGGPGATKEYFFEKDYLRNEVKDKIKDLFDVGYTDESGLRELVEKASESIKDMKISREKDLMDRFLREVKKPDGGLAVYGEKAIRDALEQKMVDLLLISEGIRRVKYTYKCPTCGEEKTFSEEPSEWPVCDKDGTPLELIGEDDMIEDLYKLAKESGAQVEIISDQSDEGKLLKQAFGGLAAVLRFIRKDNVQNVM
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_BUCAP
Sequence: MQKHLINNNIKIRILDSNIKKNSSFFLPQYATPGSSGLDLRASIKKKISLPSKEVILVPTGIAIHIDNPYITALVLPRSGLGHKNGIILGNLIGLIDSDYQGELMISLWNRSKNIFFINPYDRIAQMIFVPIIRPTFSIVDDFEETVRFGKGFGHSGVQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: OPPC_BACSU
Sequence: MQNIPKNMFEPAAANAGDAEKISKKSLSLWKDAMLRFRSNKLAMVGLIIIVLIILMAIFAPMFSRYDYSTTNLLNADKPPSKDHWFGTDDLGRDIFVRTWVGARISIFIGVAAAVLDLLIGVIWGSISGFRGGRTDEIMMRIADILWAVPSLLMVILLMVVLPKGLFTIIIAMTITGWINMARIVRGQVLQLKNQEYVLASQTLGAKTSRLLFKHIVPNAMGSILVTMTLTVPTAIFTEAFLSYLGLGVPAPLASWGTMASDGLPALTYYPWRLFFPAGFICITMFGFNVVGDGLRDALDPKLRK
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.  Also required for sporulation and competence.
What are the official names of this protein?
Oligopeptide transport system permease protein OppC, Stage 0 sporulation protein KC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCDX_ECOUT
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIAEFADL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: D106A_HYLLA
Sequence: MRTFLFLFVVLFFLTPAKNAFFDDKCDKLRGTCKNSCEKNEELTSFCQKSLKCCRTIQTCGNTTD
What is the function of this protein?
Has antibacterial activity.  Acts as a ligand for C-C chemokine receptor CCR2.
What are the official names of this protein?
Beta-defensin 106A, Defensin, beta 106, Defensin, beta 106A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: HDA_YERPE
Sequence: MLVEVLLNTPAQLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVPLDKRAYFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILSL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: Y01F_BPT4
Sequence: MIEVAKLYSIEFMSKEGKSVNTLDKNCSLIIPLAENPDFLIKDIKERKYPENIILIIKHTEDILQNTDSPFSSSEALTIKGYKRAHEYGLFDMFEDDKVKLASQPSKSKTFIIEDIKDINAFVRMVWAHFDVGLRWRMSEEERKIIETNRKFGFYR
What are the official names of this protein?
Uncharacterized 18.3 kDa protein in modB-mrh intergenic region.
Protein: LEU3_MYCSJ
Sequence: MNLAIIAGDGIGPEVIGEAVKVLDAVLPEVEKTTYDLGARRYHATGEILPDSVLEELKVHDAILLGAIGDPSVPSGVLERGLLLRIRFALDHHINLRPAKLYSGVTGPLAGNPEIDFVVVREGTEGPYTGTGGAIRVGTPHEVATEVSLNTAFGVRRVVEDAFRRAQQRRKHLTLVHKNNVLTFAGALWWRTVQEVGAEYPDVEIAYQHVDSAMIHIVTDPGRFDVIVTDNLFGDIVTDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHVGETDAAARVDKAVEAHLSSRGDQELGTAAVGDRIVGLL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y056_OSHVF
Sequence: MPLEIEVSESEMKEFKESTIDDDLESVSSEETLTQSMVDVSEEDEGLYNDITVEEKPSGDGCEEIESDEGEFDYIPIFNERTIKEMLLPYSSWTEYLTNSRAILPSITFDDKSDYDLDMRGWRQFPLAPILAEKCSGIYFFLQTLSGKKLLVDGPTWVPVSWLVCTFANVIEEADTRDISVVSNEKLQRLWDERIIGPDNDRRRKEDSKARSRLTRREEHSEHHRSGKSRRERERRSSAVQEINRRHHKRYDSDDKPWGLKREDAIYQHRAGSSHGRRHHPY
What are the official names of this protein?
Uncharacterized protein ORF56.