PharMolix/UniProtQA huggingface dataset:
Protein: SY121_ORYSJ
Sequence: MNNLFSSSWKRTGGGGGGDGDIESGGGVEMAPPPGAAAGASLDRFFEDVESIKDELRDLERIQRSLHDANEGGKSLHDAAAVRALRARMDADVAAAIKKAKVVKLRLESLDRANAANRSVPGCGPGSSTDRTRTSVVAGLRKKLRDSMESFSSLRARISSEYRETVARRYYTVTGEQPDEATLDNLAETGEGERFLQRAIAEQGRGEVLGVVAEIQERHGAVAELERSLLELHQVFNDMAVLVAAQGEQLDDIETHVGRARSFVDRGREQLVVARKHQKSTRKWTCIAIIILLVLILVVVLPIVLKFVNNNKSSSSSPAPATPSPPPPTA
What is the function of this protein?
Vesicle trafficking protein that functions in the secretory pathway (PubMed:30617050).  Involved in plant defense by mediating host resistance to the rice blast fungus Magnaporthe oryzae (PubMed:30617050).  The interaction with SNAP32 may contribute to host resistance to the rice blast fungus (PubMed:30617050).
What are the official names of this protein?
Syntaxin-121, OsSYP121.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
Protein: PLY10_ARATH
Sequence: MVIFSRSFLALSTTLIILALCINSSTMAQETEDLNSHSSSNSSTANKLPNDDGAWNEHAVKNPEEVAAMVDMKIKNSTERRRLGFFSCATGNPIDDCWRCDRNWHLRRKRLANCAIGFGRNAIGGRDGRYYVVTDPSDHDAVNPRPGTLRHAVIQDRPLWIVFKRDMVITLTQELIMNSFKTIDGRGVNVAIAGGACITIQYVTNIIIHGINVHDCRRTGNAMVRSSPSHYGWRTMADGDAISIFGSSHIWIDHNSLSNCADGLIDAIMGSTAITISNNYMTHHNEVMLMGHSDSYTRDKLMQVTIAYNHFGEGLIQRMPRCRHGYFHVVNNDYTHWVMYAIGGSANPTINSQGNRFLAPGNPFAKEVTKRVGSWQGEWKQWNWRSQGDLMLNGAYFTKSGAAAPASYARASSLGAKPASVVSMLTYSSGALKCRIGMRC
What are the official names of this protein?
Probable pectate lyase 10.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
Protein: HBA_STUVU
Sequence: VLSASDKANVKAVFGKIGGQAEEFGAETLERMFATYPQTKTYFPHFDLGKGSAQVKGHGKKVAAALVEAANHVDDIAGALSKLSDLHAQKLRVDPVNFKLLGQCFLVVVASHNPALLTPEVHASLDKFLCAVGTVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RRF_STRPD
Sequence: MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEKELLSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK2_EUBDI
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, EubDi-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: OR4KE_HUMAN
Sequence: MDPQNYSLVSEFVLHGLCTSRHLQNFFFIFFFGVYVAIMLGNLLILVTVISDPCLHSSPMYFLLGNLAFLDMWLASFATPKMIRDFLSDQKLISFGGCMAQIFFLHFTGGAEMVLLVSMAYDRYVAICKPLHYMTLMSWQTCIRLVLASWVVGFVHSISQVAFTVNLPYCGPNEVDSFFCDLPLVIKLACMDTYVLGIIMISDSGLLSLSCFLLLLISYTVILLAIRQRAAGSTSKALSTCSAHIMVVTLFFGPCIFVYVRPFSRFSVDKLLSVFYTIFTPLLNPIIYTLRNEEMKAAMKKLQNRRVTFQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4K14, Olfactory receptor OR14-22.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RASF1_HUMAN
Sequence: MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPATHTWCDLCGDFIWGVVRKGLQCARLSADCKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
What is the function of this protein?
Potential tumor suppressor.  Required for death receptor-dependent apoptosis.  Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation.  When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.  Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression.  Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein.  Isoform C has been shown not to perform these roles, no function has been identified for this isoform.  Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
What are the official names of this protein?
Ras association domain-containing protein 1.
What are the subcellular locations of this protein?
[Isoform A]: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Nucleus. Note=Localizes to cytoplasmic microtubules during interphase, to bipolar centrosomes associated with microtubules during prophase, to spindle fibers and spindle poles at metaphase and anaphase, to the midzone during early telophase, and to the midbody in late telophase in cells. Colocalizes with MDM2 in the nucleus. SUBCELLULAR LOCATION: [Isoform C]: Nucleus. Note=Predominantly nuclear.
Protein: Y263_METJA
Sequence: MDYDNMVKTLEILKDVVNALECADKGNFDKALEYLEKAQKVDKDNPLVLYVKGIVLKLKGDMEKAEKYFECLENIEGTSLLSLGNLICLTFVKGEYERTLKYIEKLSRLSKPCYLSPFHKALIYIEFGEFEKALEALDEFLKIYPNLTSILRQKASILEILGKLDEALDCVNKILSIKKDDAHAWYLKGRILKKLGNIKEALDALKMAINLNENLVHVYKDIAYLELANNNYEEALNYITKYLEKFPNDVEAKFYLALIYENLNKVDDALKIYDKIISNKNVKDKLLIKSSILNKARILEKLGKIEEAVETYNKAFDNNI
What are the official names of this protein?
TPR repeat-containing protein MJ0263.
Protein: NBR1_HUMAN
Sequence: MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNNDWYSQRY
What is the function of this protein?
Ubiquitin-binding autophagy adapter that participates in different processes including host defense or intracellular homeostasis (PubMed:33577621, PubMed:24692539).  Possesses a double function during the selective autophagy by acting as a shuttle bringing ubiquitinated proteins to autophagosomes and also by participating in the formation of protein aggregates (PubMed:24879152, PubMed:34471133).  Plays a role in the regulation of the innate immune response by modulating type I interferon production and targeting ubiquitinated IRF3 for autophagic degradation (PubMed:35914352).  In response to oxidative stress, promotes an increase in SQSTM1 levels, phosphorylation, and body formation by preventing its autophagic degradation (By similarity).  In turn, activates the KEAP1-NRF2/NFE2L2 antioxidant pathway (By similarity).  Plays also non-autophagy role by mediating the shuttle of IL-12 to late endosome for subsequent secretion (By similarity).
What are the official names of this protein?
Next to BRCA1 gene 1 protein, Cell migration-inducing gene 19 protein, Membrane component chromosome 17 surface marker 2, Neighbor of BRCA1 gene 1 protein, Protein 1A1-3B.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, autophagosome. Lysosome. Cytoplasm, myofibril, sarcomere, M line. Note=In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation (PubMed:19250911).
Protein: CHN_DROME
Sequence: MATLIPVNGGHPAASGQSSNVEATYEDMFKEITRKLYGEETGNGLHTLGTPVAQVATSGPTAVPEGEQRSFTNLQQLDRSAAPSIEYESSAAGASGNNVATTQANVIQQQQQQQQQAESGNSVVVTASSGATVVPAPSVAAVGGFKSEDHLSTAFGLAALMQNGFAAGQAGLLKAGEQQQRWAQDGSGLVAAAAAEPQLVQWTSGGKLQSYAHVNQQQQQQQQPHQSTPKSKKHRQEHAAELIYASPSTSANAAQNLAQSTPTSAPSNSSGGSTSSSGGGGGRKKAAQAAAAAAAANGVHIQKRYACTHCPYSTDRRDLYTRHENIHKDEKPFQCYACLKQFNRADHVKKHFLRMHRELQYDINKTRRHVSAGSGSSGSGSSGSGSHHSGGRGNVTINSAGVNIDNAFLEAQRHPTSSSMSIVETIEAVASATDMPLAQLKQEKMDDGAGVVLPLHVGVMQQPVASSSSGSSGSHGGNGNGGSGSGLLKPKREKRFTCCYCPWSGADKWGLKRHLNTHTKPFVCLLCDYKAARSERLATHVLKVHNKRACSKCSYLADTQEEYQAHMSDVHGNVGNANGGGGAVTIYTTTTNEGVAGGGGGGGGGISGNISGGGPLQEIIVNPSSMVGWRLSANGSLIPPHDLLTGGLPNAATQKRGSERLFQYLEAEGSDPEDYARLLKMDAISRNTASVAQDFHKAGGVHELKIPANHQLLFNNKLPSQWTTREAAALLYSLSNMGGGSASSVSGSQRQKFGMRARQHSTGEDDENTPSSASSSSFSGDEFNMSATSPLKLSRHAIKLEKMDEMDAKDMGPTKAMMATAFLEAANYEQTAIELLASKRKIKVENDNDEDQENQQHQPHQQHHSQQQQQQRLQLIKSSPAYKLNNNNNNNSNNNNYYKDKTSHRNAVHHHRQDDKENNKTKSPGTAAVSVAAAAATSPPSISGPSNQTPFLTQMEYQNLNRIGTQFQNYVKDIINKYYAAETPLMLAAAAAALPTATTTGQQQQPELDIENLSPSKRRRLLSETEEYIEYLRNKEDITLTIAPKVQPPAPVTSLLKRQLDLSTPRRSPKKAAPAHSNSASNASRKSLNQLATLLPLLADAASQQEYLAAPLDFSKKSSSRKQAQPKKIRLTPEAVVTLLRDKYLNRMVRQRLGCLKCNQLRKNSSISFNYHTLGSLALHKYWRHGRLGSSSTRREKLQAALQKRISRGQADKC
What is the function of this protein?
Probable transcription factor involved in the development of the adult pattern of macrochaetae.  Required for accumulation of achaete (ac) and scute (sc) in proneural clusters.  Probably acts by binding to the proneural cluster-specific enhancers of the ac/sc complex and increasing enhancer efficiency, thereby acting as a stimulator of ac/sc expression in proneural clusters.  Also required for correct development of the embryonic/larval peripheral nervous system (PNS).
What are the official names of this protein?
Protein charlatan.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEST_HUMAN
Sequence: MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers (G-actin).  Acts in a pH-independent manner.
What are the official names of this protein?
Destrin, Actin-depolymerizing factor, ADF.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: GLGC_RHORT
Sequence: MDQITEFQLDINRALKETLALVLAGGRGSRLRDLTNRESKPAVPFGGKYRIIDFPLSNCMNSGIRRMCVITQYRAHTLIHHIQRGWGFLRAEIGEFVELWPAQQQTDKESWYLGTADAVHQNLDLIRMHDPRFVLILAGDHIYKQDYSKLLAHHIARGSDCTVACVDVPREEATGYGCVEVDNDDNIVHFLEKPANPPGIPGRPDRAFASMGIYIFNADFLYEILESDALNEASQHDFGRDIIPSQVGKARIVAHRFSQSCVYSVGRREPYWRDVGTVDAYWSANIDLVSVTPALDLYDADWPIWTYQMQRPPAKFVFDTDERRGMAKDSLVSAGCIVSGGAVTGSLLFNDVRVNSYSSVIDTVILPMGDIGRHARLTKCILDTGCRIPEGLVIGEDPILDAKRFHVTEQGITLVTPDRLALL
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: FAKD3_BOVIN
Sequence: MALVTLRRNLYHLSDFRIHGALAALKTQQVNHVHKTVKEHLCPWFWSQHPGPIRVRFHHAHCKKFHSENGNDLHPVGEPGFSQVHNWDRFEHSVKNVDEQMFYRKLNSFTSSGEILRFVSTLETLPDTMMAGALHRICEVERKDGDQRLPKEILESSAFQALCDRFGRDPSDLSNAGLVTAFQALTLLCGDPQSHLLMNLEAECQHRLERGGLDVHSLCILGETLIKLHGPGCSTLDLIIYQLQGESLETFTPEDIVTVYRLLQASPEKADQQQRFLNKINHFSLSLVSNLSPKLMSQMLTALVVLDQTQALPLVIKLSKYVVRHIARFTSEELRKVLEALIYFGHSDRFFTETLEQHVASLCLTLDPELVSRVMEYCSRKLILSEPIFNAVAETFVCQAEKFSPSQTAKLIEPFGKLNYLPPNASALFRKLENMLLTRFNHFPPKTLLRLLHSCSLIESHPVNFMAKIFSPYFLQQLQGAESYLDRLSLAQLTQLFLTSILECPFYKGPKLLPKFQVKSFLTPCSSLETPMDFHLYKSVMIGLIDLLGARLYFSSKVLTPYCYTIDVEIKLDEDGFVLPFTIDEDVHKRVALCIDGPKRFCLNSKHLLGKEATKQRHLRLLGYQVVQIPYYEIEMLKSRLELVDYLQGKLFSQNSGGHW
What is the function of this protein?
Required for normal mitochondrial respiration.  Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6.  Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity.
What are the official names of this protein?
FAST kinase domain-containing protein 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FAST kinase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CKLF1_HUMAN
Sequence: MDPEHAKPESSEAPSGNLKQPETAAALSLILGALACFIITQANESFITITSLEICIVVFFILIYVLTLHHLLTYLHWPLLDLTNSIITAVFLSVVAILAMQEKKRRHLLYVGGSLCLTAVIVCCIDAFVVTTKMRTNLKRFLGVEVERKLSPAKDAYPETGPDAPQRPA
What are the official names of this protein?
CKLF-like MARVEL transmembrane domain-containing protein 1, Chemokine-like factor superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYK_CHLCH
Sequence: MQKNTSQPTNTNEQSNQPSLNDQIVRRIEERQHLIDSGINPYPCSFNVTHHSATILTEFQDEAKTPVAVAGRIMTIRKMGKASFFNVQDSAGRIQIYLKKDDVGEAAYNMFKLLDIGDIVGVTGYTFRTKTGEISIHAESLELLTKSLRPIPIAKEKEVDGEKVVFDAFSDKELRYRQRYVDLIVNPEVRETFIKRTAIVAAMRNFFARHGWLEVETPILQPIYGGAAARPFTTHHNALDMQLYLRIANELYLKRLIVGGFDGVFEFAKDFRNEGIDRFHNPEFTQVELYVAYKDYNWMMNLVEELIYTTAMEVNKSDTTTFLGHEISVKPPFRRLTISDAIAEYTDKDIRNKSEEELRNIAKELGLELDPKIGNGKIIDEIFGEFVEPKLIQPTFITDYPTEMSPLAKEHAAQPGIVERFELIVGGKEVCNSFSELNDPVIQRERLESQAKLRLRGDEEAMVVDEDFLRAIEYGMPPCAGLGVGIDRLVMLLTGQESIRDVIFFPHLKPE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_HAEIG
Sequence: MTTQNFLVEIGTEELPPKALKTLATSFADNVEAELNQAGLTFDKIEWFAAPRRLAVKVLNLAKQQPSKEIEKRGPAVSAAFDAEGKPTKAAEGWARGCGITVEQAERIATDKGEWLVHRAKIEGQPTKNLLNDIVANALAKLPIPKPMRWADKTVQFIRPVHTVTMLLGDELIEGEILGVASARTIRGHRFLGEKEFDIQHADQYPQLLRDKGSVVADFNERKAEILAKSQAKATALGGVADIEESLLEEVTSLVEYPNVLAAKFEERFLAVPAEALVYTMKGDQKYFPIYDKDGRLLPHFIFVSNINPEDPTAIIEGNEKVVRPRLTDAEFFFKTDLKQKLVDRLPRLETVLFQQQLGTLKDKTDRIEQLAGEIAKQIGTDEAKAKRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEDEEVAVALNEQYMPRFAGDELPKSLVASAVALADKFDTLTGIFGIGQAPKGSADPFALRRAALGALRIIVEKNLPLDLEDLVKKSAALFGDKLTNQNVVADVVDFMLGRFRAWYQDEGIEVDVIQAVLARRPTRPADFDARVRAVSHFRTLDSAEALAAANKRVSNILAKADAAIGEINLTVCVEQAEKALAEAVLALRTEVQPLIAQGDYTTVLDKLANLRAPVDSFFDNVMVNAEDPALRQNRLAILNTLQGLFLQVADISVLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_NITEC
Sequence: MARVCQVTGKRPMSGHHVSHANNKTKRRFLPNLQSRRFWLESENRWIRLRLTNAALRTIDKNGIDVVIADMRARGERI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DXS_MYCBT
Sequence: MLQQIRGPADLQHLSQAQLRELAAEIREFLIHKVAATGGHLGPNLGVVELTLALHRVFDSPHDPIIFDTGHQAYVHKMLTGRSQDFATLRKKGGLSGYPSRAESEHDWVESSHASAALSYADGLAKAFELTGHRNRHVVAVVGDGALTGGMCWEALNNIAASRRPVIIVVNDNGRSYAPTIGGVADHLATLRLQPAYEQALETGRDLVRAVPLVGGLWFRFLHSVKAGIKDSLSPQLLFTDLGLKYVGPVDGHDERAVEVALRSARRFGAPVIVHVVTRKGMGYPPAEADQAEQMHSTVPIDPATGQATKVAGPGWTATFSDALIGYAQKRRDIVAITAAMPGPTGLTAFGQRFPDRLFDVGIAEQHAMTSAAGLAMGGLHPVVAIYSTFLNRAFDQIMMDVALHKLPVTMVLDRAGITGSDGASHNGMWDLSMLGIVPGIRVAAPRDATRLREELGEALDVDDGPTALRFPKGDVGEDISALERRGGVDVLAAPADGLNHDVLLVAIGAFAPMALAVAKRLHNQGIGVTVIDPRWVLPVSDGVRELAVQHKLLVTLEDNGVNGGAGSAVSAALRRAEIDVPCRDVGLPQEFYEHASRSEVLADLGLTDQDVARRITGWVAALGTGVCASDAIPEHLD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y114_METJA
Sequence: MEKVYSKFGRIEDLKEIISGLVNFTGIIRIDNALLFYIDSKLISSKFNGREKSLEEIFSQIPDEFLIEIYQGNEKEVKSALINFKPEESIVEISKLSLVFENEVILNSYNDVYKYLTYINKVIFMPKRFKNEKGIVVYKNKREVFAVYFGRKTLFGKKAISKLKTTFAVSEIIAKIEKISNEELNSLKNQYPEGVLLFGDSINDVVKKIISSKKPIILENVSLIDALSYGTCLIKIEGSEIGYIVAKDGKPVYAFLNDYDGEKSYRLLKSMCIVEDVKYSIYKLSKEEYDMFKTFQENKIPLS
What are the official names of this protein?
Uncharacterized protein MJ0114.
Protein: LTBP3_MOUSE
Sequence: MPGPRGAAHGLAPAMRQAGALGLLALLLLALLGPGGGAEGGPAGERGTGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAAGTGAGTGSSGPGLARTGAMSTGPLPPLAPEGESVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIEGPNAEGPASSQHLLPHPKPQHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSTEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPLEDTEEERGVTMDPPVSEERSVQQSHPTTTTSPPRPYPELISRPSPPTFHRFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGQCVPGPSDYSCHCNAGYRSHPQHRYCVDVNECEAEPCGPGKGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECTKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPICEDIDECRDPSTCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECSEGTPCSPGWCENLPGSYRCTCAQGYEPAQDGLSCIDVDECEAGKVCQDGICTNTPGSFQCQCLSGYHLSRDRSRCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCVCDEGFTLTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMEHAPERREVCWGQRGEDGMCMGPLAGPALTFDDCCCRQGRGWGTQCRPCPPRGTGSQCPTSQSESNSFWDTSPLLLGKSPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFTRSRPHGACVPQRRR
What is the function of this protein?
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space.  Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.
What are the official names of this protein?
Latent-transforming growth factor beta-binding protein 3, LTBP-3.
What is the protein family that this protein belongs to?
Belongs to the LTBP family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Note=Secretion occurs after coexpression with TGFB1 and requires complexing with 'Cys-33' of the TGFB1 propeptide.
Protein: TRYP_SIMVI
Sequence: LTTVISYFALVAFALVGVSYATPKASINGRIVGGEMTDISLIPYQVSVQTAISSYGFIHHCGGSIISPRWVVTAAHCAQKTNSAYQVYTGSSNKVEGGQAYRVKTIINHPLYDEETTDYDVALLELAEPIVMNYKTAAIELAEVGEEVETDAMAIVSGWGDTKNFGEEPNMLRSAEVPIFDQELCAYLNANHGVVTERMICAGYLAGGRDSCQGDSGGPLAVDGKLVGIVSWGVGCAQSNFPGVYGI
What are the official names of this protein?
Trypsin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: YTFT_ECOLI
Sequence: MMPQSLPDTTTPKRRFRWPTGMPQLVALLLVLLVDSLVAPHFWQVVLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVAGFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITAGQIVTFNSPDLSWFGSGSLLFLPTPVIIAVLTLILFWLLTRKTALGMFIEAVGINIRAAKNAGVNTRIIVMLTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMGGRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGVRSRDKT
What is the function of this protein?
Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable).  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Galactofuranose transporter permease protein YtfT.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEOC1_STAAW
Sequence: MKFEKYIDHTLLKPESTRTQIDQIIDEAKAYNFKSVCVNPTHVKYAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRFDDVQQDIEAVVKVAKGHTVKVIIETVLLDHDEIVKASELTKAAGADFVKTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADSDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase 1, DERA 1, 2-deoxy-D-ribose 5-phosphate aldolase 1, Phosphodeoxyriboaldolase 1, Deoxyriboaldolase 1.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_PROWI
Sequence: MILKILIMIPDGIFWNNKAEEIILPTNTGQIGILKNHAPLITALDIGVILIRTDKKWVPFIIMGGFALIKQNKITILVNGAESAGTLKLVQSEAAFQEATNKLENAKSKKQYVDALFLFKCAKARYQAAKQLVS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, plastid, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid membrane; Peripheral membrane protein.
Protein: CMOB_PSYIN
Sequence: MIDFTNFYSSIAKNRLSHWLRTLPMQLHEWENTHVHGQLASWIRVLNKFPDIKTSHIELKDRVEIGSATELSPGETKKLENLLQKFHPWRKGPFVIHGIHIDTEWRSDWKWDRLLPHISPLKYRYVLDVGCGSGYHMWRMRGEGAEFVVGIDPSELFLCQFEAVRHFANKEQNVHLLPLGIQELPKLGAFDTVFSMGVLYHRKSPMDHITQLQDQLVEGGELVLETLVIGGDENAVLVPQDRYAKMRNIWFLPSAQALKLWVEKCGFENVRIADINDTLTGEQRSTAWMTNESLEDYLDPNDPSRTVEGYPAPKRALLIAKKAIKALS
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: GCH1_ECOLU
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.