PharMolix/UniProtQA huggingface dataset:
Protein: RSMA_CUTAK
Sequence: MSETGLLNPASIRRIADQIGLRPTKTRGQNFVHDANTVRRIVSLAQVGAADRVIEVGPGLGSLTLGLLETGAEVVAIEIDEVLANQLPGTVAERMPGAAERLEVVLSDALDVKVIPGAEPTALVANLPYNVAVPVLLHMLAICPQWSTGVVMVQSEVADRLVAAPGSKIYGVPSAKLAWYAEAIRVGNVPPTVFWPVPNVDSGLVRITRRRPPHVDGRDPRVTRSQVFRVVDAAFASRRKMLRSALAGLCGGSMAASELITAAGIDPTARGEALDIGDLARVVEALAQAGALSDSGQV
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PC_STAES
Sequence: MTHITESEMKQKYLDLLSQKFDSAEKLATEIINLESILELPKGTEHFVSDLHGEYESFQHVLRNGSGNVRAKINDIFKDKLSQQEINDLAALVYYPEEKLKLVKNNFDSIGTLNIWYITTIQRLIDLITYCSSKYTRSKLRKALPEQYVYIIEELLYKSNEFHNKKPYYETLVNQIIELEQSDDLIIGLSYTVQRLVVDHLHVVGDIYDRGPKPDKIMDTLINYHSVDIQWGNHDVLWIGAYAGSKVCLANLLRICARYDNLDIIEDAYGINLRPLLTLAEKYYDAENPAFKPKKRPDKDVSLTKREESQITKIHQAIAMIQFKLEMPIIKRRPSFEMEERLVLEKIDYDNNEITIYNKTYPLKDTCFQTVNPNNPAELLAEEKEVMDKLLLSFQQSEKLRRHMSFLMRKGKLYLPYNGNLLIHGCIPVDENGEMESFEIEGERLSGRELLDVFEYHVRRAFDHKESTEDISTDLVWYLWTGKYSSLFGKRAMTTFERYFIEDKASHKEEKNPYYYLREDVDMIRKMLKDFGLNPDEGRIINGHTPVKEIDGEDPIKANGKMLVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHKEFNRKEKVLSMGADELSVKRVVDEELQRKKIRDTNIGKQLQDQIDILKILMHDRYLT
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: DIAA_SERP5
Sequence: MLDRIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNADNVVLTAITNDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGQQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDSTLFPHQDE
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: SYV_XYLF2
Sequence: MSQFTSSYDPTSFEARLYAEWEAAGHFKPSGVGQPYTILLPPPNVTGTLHMGHAFQQTLMDALVRYHRMCGDDTLWQVGTDHAGIATEMVVSRNMALEGRGETRDSLGREGFINKVWEWKQQSGDTIERQMRRLGVSADWSRSTFTMDAQPSAAVTEAFVRWYEEGLIYRGQRLVNWDPVLKTAISDLEVENVQEEGMLWSIRYPLSDGVTYEHIEHDAAGNETLRETRDSLIVATTRPETLLGDTAVMVHPEDRRYTALIGKTVTLPLTGRQIEVISDTYVEPTFGTGVVKVTPAHDFNDYQVGLRHRLPMIQVLDDAACIVSKTSIQSGIASGATSDTTDTPSDSDASNASNQHDTLIMPAHLAGLDRYEARKQILADLDAQGLLVAATPHTLQVPRGDRTGQVIEPYLTAQWFVRMETLAARGLELVERGAVRFVPPNWINTYRHWMENIQDWCISRQLWWGHRIPAWFDTQGCVYVGRSEAEVRAKHALGPEVTLTQDNDVLETWFSSQLWPFSTLGWPDPMAMAERGFERYLPSSVLVTGFDIIFFWVARMIMATDHFTGNVPFHDVYITGLIRDAQGQKMSKSKGNVLDPLDIIDGITLDDLVAKRTTGLMQPKLAEKIAKATRKEFPDGIAPHGADALRFTIAALATHGRDIKFDLGRAEGYKNFCNKLWNATRFVLMNTAGDTAHSPAQHQAGQDGQDVPRTPQPRTDAEQWILSRLAAVTAEAHAQFAAYRFDLLAQALYEFAWNEFCDWFVELAKPALNGDDTQAAASTRHTLLYVLETLLRLLHPLIPFITEELWCQVAPRLGIQATTLMLRPYPQPQQLETTAFANAAADVEWLKIMVSALRRIRSTLNVPPSRRISLLLQGGQEVDRRRITHFAIALHFLLKLEHIDWLSATTAAPPSATAIVGSLKLLVPLEGLIDVDAERARLDKEIKRVESEIDKSNGKLSNAVFVQNAPTAVVEQERSRLREWTTQLNGLRERRTTL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_DESHY
Sequence: MARLKDKFSNEIAPALQQKFNYKNVMQIPKLEKVVINVGVGEAIQNSKAIDAAVGDLSKITGQKPVVTRAKKSIAAFKLRTGMPIGTKVTLRGDRMYEFVDRLMNVALPRVRDFHGVSDKAFDGRGNYTLGIKEQLIFPEIEYDKIDKVRGMDIIFVTTAKTDEEARELLGMLGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: FOSB2_BACAC
Sequence: MLQGINHICFSVSNLEKSIEFYQKILQAKLLVKGRKLAYFDLNGLWIALNVEEDIPRNEIKQSYTHMAFTVTNEALDHLKEVLIQNDVNILPGRERDERDQRSLYFTDPDGHKFEFHTGTLQNRLEYYKEDKKHMTFYI
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB 2, Fosfomycin resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MB212_MOUSE
Sequence: MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL
What is the function of this protein?
Required for several aspects of embryonic development including normal development of the eye, notochord, neural tube and other organ tissues, and for embryonic turning.
What are the official names of this protein?
Protein mab-21-like 2.
What is the protein family that this protein belongs to?
Belongs to the mab-21 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly localizes to the nucleus, with some cytoplasmic localization.
Protein: RLME_CERS1
Sequence: MTTKNTSGRGQRELRVRVKTAKGRKLSSTLWLERQLNDPYVIRAKKEGYRGRAAYKILELDDKFGFLKPGGRVVDLGCAPGGWCQVAVERVNALGQRKNKPEGTVLGVDLQEVEPISGAEIHQLDFLSDDADEKVKGWLGGRADVVMSDMAAAASGHKGTDHLRIIALCEAAAAFAFDVLEEGGTFVAKVLAGGAENELQALLKKNFTKVANVKPPASRADSSEKFVVAMGFRGRASEPEEGEA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_STAAW
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP48_HUMAN
Sequence: MAPRLQLEKAAWRWAETVRPEEVSQEHIETAYRIWLEPCIRGVCRRNCKGNPNCLVGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFLQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNHACLCSHDKLHPDKISIMKRISEYAADIFYSRYGGGPRLTVKALCKECVVERCRILRLKNQLNEDYKTVNNLLKAAVKGSDGFWVGKSSLRSWRQLALEQLDEQDGDAEQSNGKMNGSTLNKDESKEERKEEEELNFNEDILCPHGELCISENERRLVSKEAWSKLQQYFPKAPEFPSYKECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPEDTDVLYIVSQFFVEEWRKFVRKPTRCSPVSSVGNSALLCPHGGLMFTFASMTKEDSKLIALIWPSEWQMIQKLFVVDHVIKITRIEVGDVNPSETQYISEPKLCPECREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKPDGEKDPDFNQSNGGTKRQKISHQNYIAYQKQVIRRSMRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILSDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH
What is the function of this protein?
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.  May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2.  May also play a regulatory role at postsynaptic sites.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 48, Deubiquitinating enzyme 48, Ubiquitin thioesterase 48, Ubiquitin-specific peptidase 48, Ubiquitin-specific protease 48, Ubiquitin-specific-processing protease 48.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYQ_ALIFM
Sequence: MSETETRPTNFIRQIIDEDLKSGKHSSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPEKEDIEYVESIKNDVNWLGFQWSGDIQYSSNYFDKLYGYAVELIEKGLAYVDELTPEQMREYRGSLKEPGKNSPYRDRSVEENLALFEQMRDGKFKEGTICLRAKIDMASSFIVLRDPVIYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFQDNRRLYDWVLENITIDCQPRQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTVSGLRRRGFTSASIREFCKRIGVTKQENMIEFSSLESCIRDDLNESAPRAMAVLEPVKLVIENYEEGKVETLNIANHPNKPEMGTREVPFTREVYIEQDDFREEANKKYKRLVLGKEVRLRGAYVIQANRIEKDEAGNITTIFCSYDEDTLGKNPADGRKVKGVIHWVSADKALPAEIRLYDRLFTVPNPGAADDFAATINPESLVVKNGFVEPSLATAEAEVGYQFERTGYFCADNKDSSADALVFNRTVGLRDTWAG
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_YERPE
Sequence: MALLDFFLSRKKPTANIAKERLQIIVAERRRGDSEPHYLPDLKRDILAVICKYIQIDPEMLHVQFEQKGDDISVLELNVTLPETEETPK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: CPLN2_DANRE
Sequence: MSVPPGSIIVSDWHRCPDSREFFSKILHKKRRRKFGLLEAPMMPPQMNVDLVRYKVFLSGKTGVGKSALAARLAGLDLPKMHYETTGIETTVVFWPVRLKESGRVLFFRFELWDCGESAMRRFDHMLLSCKEKVDAILFLFSFTDRGSFDDLTNQISRITEPSDRVVKLVVGTKFDLFMHTDVTESDVTHFQEVWGLPVFRVGGDVSAGLGEVAPLLNALAENLWHQDCMAASSVSISPQAALRETSSEIIV
What is the function of this protein?
Potential effector of the planar cell polarity signaling pathway.  Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes.  Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia.  More generally involved in exocytosis in secretory cells (By similarity).
What are the official names of this protein?
Ciliogenesis and planar polarity effector 2, REM2- and Rab-like small GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: RNPH_SHEHH
Sequence: MRPSNRTPAQSRPVTITRQFTAHAEGSVLVEFGDTKVLCTASFEEGVPRFLKGQGQGWVTAEYGMLPRSTHSRMQREAARGKQSGRTQEIQRLIGRSLRAAVDMKLLGENTIVIDCDVIQADGGTRTAAITGACVALVDALNWARGKGILKTNPLKFLIAAVSVGIYKGEPICDLEYIEDSAAETDMNVVMTETGKIIEIQGTAEGEPFSHEELLSLLELAKHGIREIVDIQKASLS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RPIA_SHESA
Sequence: MTQDEMKKAAGWAALKYVEKDSIVGVGTGSTVNHFIDALATMKADIEGAVSSSEASTQKMKALGIPVYDLNSVDKLSVYVDGADEINGHMDMIKGGGAALTREKIVAAVAEKFVCIVDNTKQVDILGKFPLPVEVIPMARSYVARELVKLGGDPVYREGVVTDNGNVILDVYNLKIINPKELEEKINAIVGVVTNGLFAKRGADVLLVGTPEGVKTFTA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: YNAC_BACSU
Sequence: MTIYEQIKDALKNKINELVSPQEVKKTLQEKYGTNPDSIILSDYCYNRYNKGISFNKHLFEYMNRSSYKYLGENSLYTGLIFRKSKGEDKEVIVGEWVNGVKSLREASVTNNQINDQAEIISKEQLVNLYNEYNQILRYEMNVLNCKPTELRHLIGRIGEFICAIQTNGTLARQTNQHGFDVVSDGRRISVKTTAQSSGFISINKNTFYDFDDFFVVQYVNDDFKVIFFGSKEEVQKISRIYGSQYEVEISLLKKLNKEYQLN
What are the official names of this protein?
Uncharacterized protein YnaC.
Protein: CRE7_PHYIT
Sequence: MRAIAILLAVVATIFASLHGVSAIIAVNAEPASSIDSASTHLNFQRRLRQTGDASDEERGNTWFSAKIAKLIEQRKINAMMTKLTKGKSKDEVSKVKQAFQDNVLDELKALVEKGFAPDSFKTALEKLRPGNKGGEDLVAYFTAYWDTFHKAKKLSGVRKQKKRVPHAADV
What is the function of this protein?
Effector that is involved in host plant infection.  Contributes to virulence during the early infection stage, by inhibiting plant defense responses induced by both PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI).
What are the official names of this protein?
RxLR effector protein CRE7, Core RXLR effector 7.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: TAF7L_HUMAN
Sequence: MECPEGQLPISSENDSTPTVSTSEVTSQQEPQILVDRGSETTYESSADIAGDEGTQIPADEDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARSQSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQMLVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
What is the function of this protein?
Probably functions as a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.  May play a role in spermatogenesis (By similarity).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 7-like, Cancer/testis antigen 40, CT40, RNA polymerase II TBP-associated factor subunit Q, TATA box-binding protein-associated factor 50 kDa, Transcription initiation factor TFIID 50 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TAF7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids.
Protein: ENV_MSVFB
Sequence: QFKRRAKYKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATQQFQQLQAAMHDDLKKVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHTGLVRDSMAKLRERLSQRQKLFESQQGWFEGLFNKSPWFTTLISTIMGPLIILLLILLFGPCILNRLVQFIKDRISVVQALVLTQQYHQLKSIDPEKVESRE
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: RNH2_CHLT3
Sequence: MDVAFESPYWKKFQYICGVDEVGRGPLAGPVVAAAVIFDRYFEPSGILEQIDDSKALRHETRVLLSSEIKKQALSFSIAEISPEVIDEVNILQATFLAMNQAIEQLSPIPEFLLIDGNRFKTTLPIPFETVVKGDSKVFSIAAASIIAKVHRDNFMINLAERYPEYGFAQHFGYPTKAHIEAIKMFGRSKVHRKSFKLSCLGEK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM158_RAT
Sequence: MLPLLAALLAAACPLPPARGGATDAPGLSGTPPNASANASFTGEHSTPRLLASAASAPPERAGPEEAPAAPCNISVQRQMLSSLLVRWGRPRGLQCDLLLFSTNAHGRAFFAAAFHRVGPPLLIEHLGLAAGGAQQDLRLCVGCGWVRGRLRAPAGAPTALPAYPAAEPGPLWLQGEPRHFCCLDFSLEELQGEPGWRLNRKPIESTLVACFMTLVIVVWSVAALIWPVPIIAGFLPNGMEQRRTTAGAPAAAPAAVPAGTTAAAAAAAAAAAAAAAVTSGVAPK
What is the function of this protein?
Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide.
What are the official names of this protein?
Transmembrane protein 158, 40 kDa BINP-binding protein, p40BBP, Brain-specific binding protein, Ras-induced senescence protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMEM158 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PA2SD_AUSSU
Sequence: NLVQFSNMIQCANHGSRPTRHYVDYGCYCGWGGSGTPVDELDRCCQTH
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation.  In terms of inhibition of platelet aggregation, superbin d is less potent as superbin a, b, and c.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 superbin d, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL21_PICTO
Sequence: MTKMSKGPRSGSRRVMTKSVKNKGMPKVNEMMKTFEVGDRAAIVINSAVPDGMPHHDFQGITGVITGMQGSCYILSFKVGNVEKKVIAAPVHLRKVQ
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: OTC_BACAA
Sequence: MSTVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRTRVSFEAGMVQLGGHGMFLNGKEMQMGRGETVSDTAKVLSHYIDGIMIRTFSHADVEELAKESSIPVINGLTDDHHPCQALADLMTIYEETNTFKGIKLAYVGDGNNVCHSLLLASAKVGMHMTVATPVGYKPNEEIVKKALAIAKETGAEIEILHNPELAVNEADFIYTDVWMSMGQEGEEEKYTLFQPYQINKELVKHAKQTYHFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHAQKALLVSLFKNVEELS
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CL1A_HOTJU
Sequence: MNSFVVVLLLFIAILCNAEQESDENARSCNRLGKKCNSDGDCCRYGERCLSSGVGYYCKPDFGP
What is the function of this protein?
May increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors (ITPR) of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells.
What are the official names of this protein?
Phi-buthitoxin-Hj1a, Phi-BUTX-Hj1a.
What is the protein family that this protein belongs to?
Belongs to the scorpion calcin-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBX_PHATC
Sequence: MTPSLGSFIASLFAGAFIALAIGGVLVFISQSDRVTRS
What is the function of this protein?
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.
What are the official names of this protein?
Photosystem II reaction center X protein.
What is the protein family that this protein belongs to?
Belongs to the PsbX family. Type 1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NTPTH_STAMF
Sequence: MKNYIITGRPGIGKSTLFNNIINTLRKSGIIVGGIKSPEVRDSKGFRIGFKIIDLMSNEEGWLAKRNYYSTIKVGKYGIVLDESSRIIREALRKALEKADVIGIDEIGPMELKIHVFRTMLEQVLNSDKPKILVIHYRLRDPSILDKIYRVENEKYVLTEHNRDLLNKVLPQKIVMEIKQIIKK
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  May hydrolyze nucleoside diphosphates with lower efficiency.
What are the official names of this protein?
Nucleoside-triphosphatase THEP1, NTPase THEP1, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.