PharMolix/UniProtQA huggingface dataset:
Protein: RK22_PEA
Sequence: MALSLAINVPPVRDNLLRPQPFQSQFRPNLLKFPIPSSARIRCSSSSSFNDISLKTVTPDNKNSFVCRFNATQLEVQETNQPYAETYAVGRHIRMSADKARRVVDQIRGRPYEASLMVLELMPYRACEAIIKIVFSAGANASHNLGLSKSSLFISKAEVNEGKTLKRVRARAQGRANQILKRTCHITITVRGLPDESDKEENSS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic, CL22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMH_MARSD
Sequence: MSKLQFVWVGKLKEPFFRDACAHYTKKLGRFHKLDETILKDAPGKLPPMDKVQHEGKAIMARIKPSDMLICLDEKGKEMTSVELSKHLQRWTEDPNLTPTFVIGGPFGLADEVKNAARVKLSLSKMTLPHELARTMLLEQLYRAASILRGSPYHHV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_THET8
Sequence: MLRFAVLGHPVAHSLSPAMHAFALESLGLEGSYEAWDTPLEALPGRLKEVRRAFRGVNLTLPLKEAALAHLDWVSPEAQRIGAVNTVLQVEGRLFGFNTDAPGFLEALKAGGIPLKGPALVLGAGGAGRAVAFALREAGLEVWVWNRTPQRALALAEEFGLRAVPLEKAREARLLVNATRVGLEDPSASPLPAELFPEEGAAVDLVYRPLWTRFLREAKAKGLKVQTGLPMLAWQGALAFRLWTGLLPDPSGMEEAARRALGV
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CA1C_CONTE
Sequence: GCCSRPPCIANNPDIC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin Tx1C, Alpha-conotoxin-like 1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NAR1_BOTFB
Sequence: MSAILSADDLNDFISPGVACIKPVETLPAAKPSADNELEISFNTDAPLPSDLPPAQISLTDCLACSGCVTSAEAVLVSLQSHAEVLSQLDSAPGIRLHKSATGTGVSVEGLEQGGKIYVASVSPQSRASIAATFGVTEREAGYMIEHLLSGPKGIKNRAVYRNAFQWVVDTNITREACLVLGAEEVIASMNGTEETKKPILTSSCPGWVCYAEKTHPHVLPHLSRMKSPQALMGTLIKTTLSRKLGISPERIWHVAVMPCFDKKLEASREELTDAVWEGTGTRGVRDVDSVITSKELLMLADSRRIDFSKLPRTPLPSSSHIPFPDPTLNSFLFPSNRRSSSNGSRDAGSSGGNLHYALHYFASQHKGSSVQTIKGRNADVVDYTVVADNGDILLKAARYYGFRNIQNLVRRLKPARPSRMPGGKPIGSARRPNGKATGPDYTYVEVMACPGGCTNGGGQIKVDDPINTSRLEGDSKPGPQEQKMWLAQVDEAYFSGDDSTVCSSVDDRNDLVEGISPSYIKDTLSHWATTTGLDLERLVYTTYREVVSDVGKNAGDAERVIEIANKIGGGW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: YECE_ECO57
Sequence: MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKPEVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQLPATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNQVILDSRPVHAARPHSEAIRDAQRKKPKVPVHAVLTATNPLIRFIGSDDMTQNRELFQVWLQKLAQWHQTTTPYLFLHTPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF
What are the official names of this protein?
UPF0759 protein YecE.
What is the protein family that this protein belongs to?
Belongs to the UPF0759 family.
Protein: PRRC1_XENTR
Sequence: MMEESGIETTPPSTPPPSTAGTSVAAATTAIATPIPPVLSSPLAAPAFSPLPSFAQPSFSTPVPSSVAPPRSSVPFTYASALPVTGVHSPPVNTSVPAAFSSPLPAFSSPSSFPPPPLNTTPGPVLSAPPMVPPVGGFSMSSTYDITKGHAGRAPQTPLMPTYSAAPVTVLPNPVTLQAPVAGSGSSITFPEEPEDPRVHTVHDEGSAGGIWGFIKGVAGNPMVKSVLDKTKHSVETVITTLDPGMASYIRTGGEMDIVVTSIKEVKVAAVRDAFQEVFGMAVVTGEDGQSNIAPQPVGYAAGLKGAQERIDSLRRSGMIHEKQPAVSVENFIAELLPDKWFDIGCVIVDDPVHGIRLEAFTQATPVPLEYVQQAQNFTPQDYNLRWSGLSVTVGEVLERSLAHVSRTDWHVAFTGMSRRQMIYSAAKALAGMYKQRLPPRIL
What are the official names of this protein?
Protein PRRC1, Proline-rich and coiled-coil-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRRC1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: AKR1_LACK1
Sequence: MKQIDSEDSITVPNDTPEDNSASSMQPVMSNLSIEEHQSENEPIEQEQADAKDPLLSKYHLACQQGDLATVKEIIENGVIDLKHDYDDVERVSGLHWASINNRLSVVRYLISKDVDVNFQGGELNATPLHWAARYGYVYIVDYLLEHGADPSVTDAQGFNLLHLSINSSNIMLVIYVLFFVIDDKLDIDCVDPNGRTALLWAAYQGDSLSVETLLKFRASVKATDKGGFTPLHWGTVKGQAQVLKHLIENGADFFQKTADGKNCFAIAHDMNTTGSLVGALYQCGFNKEGFAIPVYFKKSLHTKLVTFFAPWIFIGVLFKCFASIHPIFSLIFSILLGLGMRYTLKKYVIPAYAQRNTRQSFLKTPFLAGVFSGSVFWASYTWLTRIMPLTLIEEPITNLLFFAGVVLLASLFVKLVRSDPGLIPEETDHSKVKETIKELLNVGKFDAKHFCISTWVRKPIRSKFSNFSRALVTRFDHFCPWIYNDIGLRNHKTFLFFILCLETCIFVFLKLCMEYFDVLEDTFEDDYDLNCGIFGEDLCAGFFFDTFTFLVLAWTCFQGIWVGFLTFVQLFQTAKGVTNYEFSTLSKRRHNHDSSVNEYFTTTPLELIDEEEADPLNPVIPGNNPRDPLMQKSRTCFGICWTLTGLDQFVMVIKETFGVAQREEPRNNILSFKISTDYGWRTNLKDFWLTSDITAPTWQRFLYSPSCSKALLNGEEVDYFKLYKLPERHYLAEEIV
What is the function of this protein?
Palmitoyltransferase specific for casein kinase 1.
What are the official names of this protein?
Palmitoyltransferase AKR1, Ankyrin repeat-containing protein AKR1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: C10_MOUSE
Sequence: MASASAQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEGVLKFARLVKSYEAQDPEIASLSGKLKALFLPPMTLPPHGPASGSSVAAS
What is the function of this protein?
In brain, may be required for corpus callosum development.
What are the official names of this protein?
Protein C10.
What is the protein family that this protein belongs to?
Belongs to the UPF0456 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM19_CAEEL
Sequence: MFRPAAREVVKLPVRYFSCKSEPTRAAPVTKKTSREEIAGLIPAFPEIYPDFLQSPVWNRRNALKEELERQDMLERRMNIDIPEFYVGSIVAVTSSDKNLGSKEHRFVGICIRREKEGLLHQFTLRNTIENIGVEVVYDLYNPTIKKIETLKLEKRLDNDLSYLVDALPEYSTFDFHMEPQAHPAGTPIPVNECKVKLKTPPWTRRWEVASVRGIEDTWTQATPWFKRKLHKTIVNDYEKYDLIADYRTSSTKEQEVFVQKQMQKFEKERHAAGLTRRRILKSAAAYK
What are the official names of this protein?
Probable 39S ribosomal protein L19, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ENV_HV19N
Sequence: MRVKGIQRNWQHLWKWGTLILGLVIICSASDNLWVTVYYGVPVWEDADTPLFCASDAKSYSSEKHNVWATHACVPTDPNPQEIAIENVTENFNMWKNNMVEQMQEDIISLWEESLKPCVKLTPLCITLNCTNVNSANHTEANNTVENKEEIKNCSFKITTERGGKKKEEYALFYKLDVVPISNGNKTSYRLIHCNVSTIKQACPKVNFDPIPIHYCAPAGFAILKCRDKEYNGTGPCKNVSTVQCTHGIKPVVSTQLLLNGSLAEEDIRIRSENFTDNTKVIIVQLNNSIEINCIRPNNNTRKSIPIGPGQAFYATGDIIGDIRQAHCNVSRIKWREMLKNVTAQLRKIYNNKNITFNSSAGGDLEITTHSFNCRGEFFYCNTSGLFNNNISNINNETITLPCKIKQIVRMWQKVGQAMYALPIAGNLVCKSNITGLILTRDGGNNNDSTEETFRPGGGDMRDNWRSELYKYKTVKIKSLGVAPTRARRRVVEREKRAVGLGAVFLGFLGAAGSTMGAASITLTAQVRQLLSGIVQQQSNLLRAIEAQQHLLQLTVWGIKQLQSRVLAIERYLKDQQLLGIWGCSGKLICTTNVPWNTSWSNKSYNEIWDNMTWLEWEREIHNYTQHIYSLIEESQNQQEKNEQDLLALDKWASLWNWFDISNWLWYIRIFIMIVGGLIGLRIVFAVLSIVNRVRQGYSPLSFQTLTHHQREPDRLGKTEEGGGEQDRDRSTRLVSGFLALAWDDLRSLCLFSYHRLRDLVLIAARTVELLGRSSLKGLRLGWEGLKYLWNLLLYWGRELKNSAINLLDTIAIATANGTDRVIEVAQRAYRAILNVPTRIRQGLERALL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: Y1625_HAEIN
Sequence: MKLKLFFHIVLLCFSLPIWAMKTVDVTASPKMDDQARMNLAQEFANKQQWIDVFNIMYPMALEGNITAQSNLGMLYNLGRGTVRDYEKAYWWFSEAAEKGSVKGLNNLGVMYLRGDYVKQNTEQAIKLFERTAQAKDTDAMMMLSNIYRLQNQPEKIIGMAEESR
What are the official names of this protein?
Uncharacterized protein HI_1625.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KAD_LACGA
Sequence: MINLILLGLPGAGKGTASESIVDKYHLAHISTGDMFREAMANETPVGLEAKSYIDKGDLVPDEVTAKLVEERLKQPDTKNGFILDGFPRTTVQAELLEGITKRLEKPLTNVIAIDVDEDVLIKRLSARYICKNCGATYNKISNPTKVEGTCDRCGGHEFFQREDDKPEVVKNRLEVNKKMNTPLRDFYEEKGILSTVNGEQTPEKVFEDIDKILSKD
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR5_CHLAE
Sequence: MDYQVSSPTYDIDNYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLLFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPRIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQETSVGF
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation (PubMed:9343222).  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor (By similarity) (PubMed:9343222).
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS5_LISMH
Sequence: MIVIIDYDTGNTKSISKALDFIGLQNKISSDATEISQADGVILPGVGAYPEAMKELTRRGLDKTLKEIAATGKPILGVCLGMQLLLESSNEHSFTSGLGLIPGHVEKLPEEPEFAVPHMGWNQLQIKRATPLTKQLDGEYVYYVHSYYANCPEEYIIATSGYSIEVPGMINNGNIYGAQFHPEKSGQIGLEILKGFKEVTYSCKSSQQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_THAPS
Sequence: MAKKILYQDNARRALERGMEIMVEAVSVTLGPKGRNVVLEKTYGSPQIVNDGVTIAKEISLEDHIENTGVSLIRQAAAKTNDVAGDGTTTATVLAYAMVKEGLKNVAAGANPISIKLGMEKATQYLVMQINEFAQPVEDIQSIKQVASISAGNDDVIGALIADALAKVGKEGVISLEEGKGIVTELEITEGMKLEKGFISPYFITDTEKMEVCFENPYILLTDKRITLVQQDLLPILEQITKTKRPLLIIAEDVEKEALATLILNKLRGIVNVVAIRAPGFGELRKLMLQDIAVLTGGTVITQDAGLSLDNIQVNLLGQARRIIVNKDTTTIVGDGLEIENIKARCEQLRKQVNIAETSYEKEKLQDRIAKLSGGIAVIRVGAVTETEMKDKKLRLEDAINATRAAVEEGIVPGGGATLAHLSENLVTWSKTNLKEDELIGALIISRAIVAPLKRIAENAGINGPVVIGKVQEQEFEIGYNAAKNLFGNMYDEGVVDPAKVTRSGLQNATSIASMILTTECIIVDDIEKVK
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, chloroplastic, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NPIIA_ASPFN
Sequence: MRFISASSLLLALAPTLNAVPVEVAGSAQGLDVTLSQVGNTRIKAVVKNTGSEDVTFVHLNFFKDAAPVQKVSLFRNGMLPNLNLATTEVQFQGIKQRLITEGLSDDALTTLAPGATIEDEFDIASTSDLSEGGTITINSNGLVPITTDNKVTGYIPFTSNELSIDVDAAEAASVTQAVKILERRTKVTSCSGSRLSALQTALRNTVSLARAAATAAQSGSSSRFQEYFKTTSSSTRSTVAARLNAVANEAASTSSGSTTYYCSDVYGYCSSNVLAYTLPSYNIIANCDLYYSYLPALTSTCHAQDQATTTLHEFTHAPGVYSPGTDDLGYGYSAATALSASQALLNADTYALFANGTYSSLLSFVNPLLTPDNSCQPQLLDARTCNRQFGRSTSCKVYWKAVE
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog AFLA_065450, Deuterolysin AFLA_065450.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOVP_CLBVS
Sequence: MASLINVSSLVNRVKLDQSIIGSDEINKLYGSDAPLVFKDEVKMVIPGNAEGEAIKLQANILTADRLQSIRNAKVNGKEAAYLHLGFVPIAIRSLLPSGNEQIWGRCALVDTSRTRAETAVIDEFEFKFTKKQPFAAKLLTINAAVDINCKVSVGSIQVLLELHGVDLREERSVAAIITGLTCTPTNKMVLLHKIECDTPKWSLCNIIEQVEDEEESKKAFENMFNASSSNLIDLGQEQWLDEGKRTPLIGSLAIKGFGRKVMPVRRRNLTTRNLMKDYVSHVKSETASLKRSQSGRDWGNDRLRKYLEEQALEQARSSTDHQLVKAPKFKTIEVTGLETVHDLKDKIDKAESSTASDTGTK
What is the function of this protein?
Suppressor of viral-induced RNA silencing.
What are the official names of this protein?
Putative movement protein, MP, Cell-to-cell transport protein.
Protein: PHY_PINSY
Sequence: MASNSRHTQSQSTGSNNRRSSTNTNTTTNKATAMAQYNSDARLLQVFEQSGESGKSFDYTRSIQVHNRAVPEQQITAYLSRIQRGGRIQPFGCVLAVEETTFRIIAYSENEEMLDLGAQSVPSMEKPQQDVLTIGTDVRTLFTAASAHSLEKAAVAQEISLMNPIWVHCKNSRKPFYAIVHRIDVGMVIDLEPLRTGDAFMSAAGAVQSQKLAVRAISRLQSLPCGDVGLLCDTVVENVRELTGYDRVMVYKFHEDEHGEVVAEIRRSDLEPYLGLHYPATDIPQASRFLFMQNRVRMICDCMATPVKVIQSEELMQPLCLVGSTPSAPHGCHAQYMANMGSIRSLLMAVIINGNDDEGGGSGRNSMKLWGLVVCHHTSPRAVPFPLRYACEFLMQALGLQLNMELQLAAQLTEKHILRTQTLLCDMLLRDAPMGIVTQSPSIKDLVKCDGAALYYGGMCWMLGVTPTEAQIKDIADWLLEHHGDSTGLSTDSLADAGYPGAASLGDAVCGMASARITSKDFLFWFRSHTAKEMKWGGAKHHPDDKDDARRMHPRSSFKAFLEVVKRRSLPWDNVEIDAIHSLQLILRCSFRDIDDSGTKTMVHSRLNYLRLQGIDELSSVASEMVRLIETATAPILAVDYNGLVNGWNAKVAELTGLPVGEAMGMSLVQDLVFEQSVERVEKMLHNALRGEEEKNVEMMLKTFGPQKEKEAVILVVNACSSRDFTDNIVGVCFVGQDVTSQKVVMDKFIRIQGDYRSIVQSPNPLIPPIFASDEYACCSEWNAAMEKVTGWTHDEVIGKMLVGEIFGGCCRLKGQDAVTKFTIVLHQCNHGQEIEKFPFAFFDKQGKYVEALLTANKRTDADGRITGSFCFFRIASSELQHALEVQRQQEKKCFARLKELAYIRQEIKNPLYGMMFTRKLLEETDLSDDQKQFVETSAVCERQMQKVMDDMDLESLEDGYMELDTAEFILGTVIDAVVSQGMIVLREKGLQLIREIPGEVKTMRLYGDEVKIQQILADFLLNVLRFTPSPEGWVAIKVFPTLKQLGGGLHVVHLEFRITHPGLGLPAELVQDLFDRSQWATQEGVGLSMCRKLLKLMNGDVRYIRESGICYFLVNVEFPMAQREDAASIK
What is the function of this protein?
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region.  Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses.  Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc.  It also controls the expression of its own gene(s) in a negative feedback fashion.
What are the official names of this protein?
Phytochrome.
What is the protein family that this protein belongs to?
Belongs to the phytochrome family.
Protein: RS20_SYNWW
Sequence: MAKSKTPAKRARRAEANRLRNKAYKSKLKTAIKNYENAIIAEDLDTASNKLLQVTSLLDRSITKGILHKNNVARKKSALSKKLNSISQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SCX2_CENGR
Sequence: KDGYLVNKSTGCKYSCIENINDSHCNEECISSIRKGSYGYCYKFYCYCIGMPDSTQVYPIPGKTCSTE
What is the function of this protein?
Binds to sodium channels (Nav) and inhibits them.
What are the official names of this protein?
Toxin Cg2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: THRC_MYCS2
Sequence: MSAAKAAVHQPWPGLIEAYRDRLPIGDDWTTVTLLEGGTPLIHAKRISELTGCTVHLKVEGLNPTGSFKDRGMTVAVTESLARGQQAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQVDGNFDDCLELARKLTADFPTIALVNSVNPYRIEGQKTAAFEIVDALGTAPDVHALPVGNAGNITAYWKGYSEYHRDGVSDRLPRMLGTQAAGAAPLVTGAPVKDPETIATAIRIGSPASWNSAVEAQQQSDGRFLAATDEEILAAYHLVARTEGVFVEPASAASIAGLLKSVEDGWVKRGSTVVCTVTGNGLKDPDTALKGMPQVTPVPVDPSAVVAELGLS
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: PRIO_CANLF
Sequence: MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGTHSQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYLLGSAMSRPLIHFGNDCEDRYYRENMYRYPNQVYYRSVDQYNNQSTFVHDCVNITVKQHTVTTTKGENFTETDIKMMERVVEQMCITQYQRESEAYYQRGASVILFSSPPVILLVSFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: OXDD2_CAEBR
Sequence: MLPKIAVIGEGVIGCTSALQIAKAIPNSKITIFHDKPFENSCSAGPAGLFRIDYEENTEYGRASFAWFSHLYRTTKGAETGVKLVSGHIQSDNLESLKQQQRAYGDIVYNFRFLDDRERLDIFPSPSKHCIHYTAYASEGNKYVPYLKRLLLEQKVEFQQKNVENLDTIADAGYDVIVNCAGLYGGKLAGDDDQCYPIRGVILEVDAPWHKHFNYRDFTTFTIPKENSVVIGSTKQDNRWDLEITDEDRNDILSRYIELHPGMREPKILKEWSALRPGRKHVRIESQQRKTTETGKEYTVVHHYGHGSNGFTLGWGTAIEATKLVKKALGL
What is the function of this protein?
Selectively catalyzes the oxidative deamination of D-aspartate and its N-methylated derivative, N-methyl D-aspartate.  Highest catalytic efficiency for D-Glu followed by D-Asp and NMDA.  May play a role in the egg-laying events and early development of the worm, in addition to quality control of the germ cells.
What are the official names of this protein?
D-aspartate oxidase 2, DASOX 2, DDO-2.
What is the protein family that this protein belongs to?
Belongs to the DAMOX/DASOX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_FRATF
Sequence: MQAFKKLTSSAIPLWLSDIDTDMIIPANFLTQTTKDGYGKSLFHNLKEKDSSFVFNNPDYSNSEILIAGDNFGCGSSREHAVWALTQAGIKVIIAPSFSDIFFNNAAKNGLLLISLDKDTVKELCDKAEDPKFSMTIDLQEQTVSADGSIYSFDYDPFRKDCLIRGLDDMTYLIEHLDIIKQFEQSQRG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: Y47_BPT7
Sequence: MRDPKVIQAEIAKLEAELEDVKYHEAKTRSAVHILKNLGWTWTRQTGWKKPEVTKLSHKVFDKDTMTHIKAGDWVKVDMGVVGGYGYVRSVSGKYAQVSYITGVTPRGAIVADKTNMIHTGFLTVVSYEEIVKSR
What are the official names of this protein?
Protein 4.7, Gene product 4.7, Gp4.7.
Protein: XNI_ECOLU
Sequence: MAVHLLIVDALNLIRRVHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRTAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.