PharMolix/UniProtQA huggingface dataset:
Protein: RECR_PSEMY
Sequence: MSFSPLIRQLIDSLRILPGVGQKTAQRMALQLLERDRSGGQRLAQALNAAMEGVGHCKRCRSLSEDEVCQLCLDERRDDSLLCVVEGPMDVHAVEQTGFRGRYFVLKGHLSPLDGLGPEAIGIPELLERIEAGAFSEVILATNPTVEGEATAHYIAQILAGKGLIASRIAHGMPLGGELELVDGGTLAHALAGRRPISL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RIMM_STRPC
Sequence: MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDKDRFVQEVTIVSHRKQKHFDIIKFKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYHQIIGMAVYEKDVLIGHVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLSVDVPNKRVDVELMEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_BURP1
Sequence: MASKIETLKANLEAALGARAVSLVEAVGELTLVVKASDYLEVAKQLRDDRSLGFEQLIDLCGVDYQTYGDGAYDGPRFAAVLHLLSVANNWRLRVRVFASDDDLPIVPSVVDIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPQEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OPP26_HAEIF
Sequence: MKKTLAALIVGAFAASAANAAVVYNNEGTNVELGGRLSVIAEQSNSTRKDQKQQHGELRNAGSRFHIKATHNFGDGFYAQGYLETRLVSDYQSSSDNFGNIITKYAYVTLGNKGFGEVKLGRAKTISDGITSAEDKEYGVLENKEYIPKDGNSVGYTFKGIDGLVLGANYLLAQKREAYKTATATPGEVIAQVISNGVQVGAKYDANNIIAGIAYGRTNYREDLATQDKSGKKQQVNGALSTLGYRFSDLGLLVSLDSGYAKTKNYKDKHEKRYFVSPGFQYELMEDTNVYGNFKYERNSVDQGKKAREHAVLFGVDHKLHKQVLTYIEGAYARTRTNDKGKTEKTEKEKSVGVGLRVYF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane protein P2, OMP P2.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CXAR_MOUSE
Sequence: MARLLCFVLLCGIADFTSGLSITTPEQRIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPSDNQIVDQVIILYSGDKIYDNYYPDLKGRVHFTSNDVKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKFLLTVLVKPSGTRCFVDGSEEIGNDFKLKCEPKEGSLPLQFEWQKLSDSQTMPTPWLAEMTSPVISVKNASSEYSGTYSCTVQNRVGSDQCMLRLDVVPPSNRAGTIAGAVIGTLLALVLIGAILFCCHRKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERAPQSPTLAPAKVAAPNLSRMGAVPVMIPAQSKDGSIV
What is the function of this protein?
Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity.  Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes.  The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair.  Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases.  It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
What are the official names of this protein?
Coxsackievirus and adenovirus receptor homolog, CAR, mCAR.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cell junction, adherens junction. Note=In epithelial cells localizes to the apical junction complex composed of tight and adherens junctions. In airway epithelial cells localized to basolateral membrane but not to apical surface. SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
Protein: LRL3_ARATH
Sequence: MENGNGEGKGEFINQNNDFFLDSMSMLSSLPPCWDPSLPPPPPPPQSLFHALAVDAPFPDQFHHPQESGGPTMGSQEGLQPQGTVSTTSAPVVRQKPRVRARRGQATDPHSIAERLRRERIAERMKSLQELVPNTNKTDKASMLDEIIEYVRFLQLQVKVLSMSRLGGAGSVGPRLNGLSAEAGGRLNALTAPCNGLNGNGNATGSSNESLRSTEQRVAKLMEEDMGSAMQYLQGKGLCLMPISLATAISSSTTHSRGSLFNPISSAVAAEDSNVTATAVAAPEASSTMDDVSASKA
What is the function of this protein?
Transcription factor that regulates the development of root hairs (PubMed:19675148).  Does not seem to be involved in the regulation of sperm cell development (PubMed:28585562).
What are the official names of this protein?
Transcription factor LRL3, Basic helix-loop-helix protein 82, AtbHLH82, bHLH 82, Protein DEFECTIVE REGION OF POLLEN 3, Protein LJRHL1- LIKE 3, AtLRL3, Transcription factor EN 96, Transcription factor bHLH82, bHLH transcription factor bHLH082.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHP14_MOUSE
Sequence: MAADLGQIPDVDIDSDGVFKYVLIRVHLAEPSGDPAKECKEIVRGYKWAEYHADIYDKVSGELQRNGYDCECLGGGRISHQSQDRKIHVYGYSMGYGRAQHSVSTEKIKAKYPDYEVTWADDGY
What is the function of this protein?
Exhibits phosphohistidine phosphatase activity.
What are the official names of this protein?
14 kDa phosphohistidine phosphatase, Phosphohistidine phosphatase 1, PHPT1, Protein histidine phosphatase, PHP.
What is the protein family that this protein belongs to?
Belongs to the janus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_RICCK
Sequence: MEIDLLQYEKKYQEYIVAGIDEAGRGPLAGPVVASAVVIDNTNIITGIKDSKKLSKRKRELLYEQITSNYIWSTAIISHTEIDEINILEATKKACSIAAANLTIKPEIVLVDGNMQFNDKRFVSIIKGDNLSLSIAAASIVAKITRDRLMLDLSTEFPQYLWYKNSGYGTKEHIQAINTHGLSPYHRKSFRYSCFI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMTA_CITK8
Sequence: MKLRWFAFLVVLLAGCSSKQDYKNPPWNAEVPVKRAMQWMPISEKAGEAWGVSPRLITAIIAIESGGNPTVVSKSGAVGLMQLKASTSGRDVYRHMGWSGEPSTSELKNPERNISMGTAYLSILEHGSLAGINDPQVMQYALVVSYANGAGALLRTFSSDRKKAIEKINDLSADEFFEHVAKNHPAPQAPRYIWKLQQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CLPP_STRZP
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MODC_BRUAB
Sequence: MSGLTVSIRGRNGAFAIEAGFAAEGGVTALFGHSGAGKTTLLKMIAGTLRPENGRIAVGDFTLFDAQKGINLPPEKRRIGYVFQDARLFAYMSVKRNLTYARWAGHRPATRSFDEVVALLGIGHLLDRRPSTLSGGERQRVAIGRALLSDPALLLLDEPLSSLDHARRQEILPFIERLRDESHVPIVYVSHEIDEVARLADQIVLLSAGRVTASGAAADIFPLIDAESEGGGVLLEGIVSAYDERYKLAEIDLGGASFQLSDAGLKQTMHVRLRVRARDVSIARKIPEAISIRNLLPVTVTGIERGEGPNAHVFLDFRGRRLGARLTRRSVDDLGLSVGDQVVALVKAVSVDRAAIREK
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AAEA_ECOBW
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQILFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AURB_CHLAA
Sequence: MSWRGSGRSNFRSRSSSNGGSTFSGGSAGGPPLIVMMGLAFGAGLIMLIVMIASNATAGGFVAATPRPTATPRPTAAPAPTQPPAAQPTTAPATQAANAPGGSNVVNETPAQTVEVRAAPDALAFAQTSLSLPANTVVRLDFVNQNNLGVQHNWVLVNGGDDVAAAVNTAAQNNADALFVPPPDTPNALAWTAMLNAGESGSVTFRTPAPGTYLYICTFPGHYLAGMKGTLTVTP
What is the function of this protein?
Probably a soluble electron acceptor for the integral membrane protein electron transfer alternative complex III (ACIII).
What are the official names of this protein?
Auracyanin-B, Ac-B.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Possibly located on the extracellular face of the cell membrane.
Protein: RFX4_DANRE
Sequence: MHCGLLEEPDMDSTESWIERCLNESESKRFSSHSSIGNISNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKLDSQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVNETGKKEVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILKRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSREDQRRLIIQLYQEFDRLLEDQSPIEAYIEWLDSMVERCVVRVAGKRPGSLKRVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGAPADTGEELMLMSSTPTSTSPAPYSPAKSVHSVGVPAVGSPNSAQSPEYTSISATTGAVQSYTWSLTYTVTTSGGSPTEPGSQLSCMRGGPALHGSSSAHRMPVYPHRDEHGYTGSYNYSSYANQHHHAIQSQYSSLTHEAGLPTPLHYSSYHRTSAQYPLNSQMSRMESCLMSGSPLLHSSPVTPRWPDVPSANSCYSSPTVHASRYSTGDMYSPLAPRRNSEYEHAQHFPGFAYINGEATTGWAK
What is the function of this protein?
May activate transcription by interacting directly with the X-box.
What are the official names of this protein?
Transcription factor RFX4, Regulatory factor X 4.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMD_LIMF3
Sequence: MRIDILSLFPDMFDATLGQSIVGRAQDDGFVDIKVTDFRQYTTDKHRHVDDAPFGGGAGMLLQAQPIFDAMDAIEQETKDTYPKGRVILMDPAGRRFDQDFAMELAQEEHLTFICGHYEGYDERIRQLVTDEASLGDYVLTGGELAAMVMVDATVRFVPGVLGNMSSPMGDSFSNGLLEYPQYTRPADFRGMKVPEVLTSGNHEKIREWRMRESLKRTLERRPDLLKNAKLSREQQIILQDLKLDLDPDAPK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_XANCP
Sequence: MTRKLVLLRHGQSQWNLDNRFTGWVDVDLTEQGRQEAAAAGKLMKDEGLQFDVAYTSVLKRAIHTLQGALKELDQDWLPVHKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDIPPPAMDVTDPGHPGHDRRYATLDRNALPGTESLATTLVRVLPYWHDAIAPQLKAGQTVLVTAHGNSLRALYKYLNDISNAQILELNIPTGIPLLFELDDNLQVQSYRYLGDPEAAKRAAEAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: FMT_RICPA
Sequence: YFSYNDKIIKILEAEYLNADHHFTSGTVISDKLEIACGSGILRVKKLQQESKKALNIEEFLRGTNILKDTVLK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LHPL7_HUMAN
Sequence: MLSSVWVALGLSLTCTSAFSLISPAWFQTPTFSFGILTYCSWPQGNSWNQSCVTFSSLEDIPDFAWKVSAVMLLGGWLLLAFNAIFLLSWAVAPKGLCPRRSSVPMPGVQAVAATAMIVGLLIFPIGLASPFIKEVCEASSMYYGGKCRLGWGYMTAILNAVLASLLPIISWPHTTKVQGRTIIFSSATERIIFVPEMNK
What are the official names of this protein?
LHFPL tetraspan subfamily member 7 protein, Transmembrane protein 211.
What is the protein family that this protein belongs to?
Belongs to the TMEM211 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KA11L_LYCMC
Sequence: MNKVCFVVVLVLFVALAAYVSPIEGVPTGGCPLSDSLCAKYCKSHKFGKTGRCTGPNKMKCKCLV
What is the function of this protein?
This recombinant toxin inhibits the mammalian voltage-gated potassium channels Kv1. 3/KCNA3 in vitro with an IC(50) of 26. 40 nM.
What are the official names of this protein?
Toxin KTx8, LmKTx8.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 11 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLSA_SALEP
Sequence: MAWAMDNAILETILQRVRPLIGQGKVADYIPALASVEGSKLGIAICTVDGQHYQAGDAHERFSIQSISKVLSLVVAMRHYPEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRALCGVSDITYDATVARSEFEHSARNAAIAWLMKSFGNFHHDVPTVLQNYFHYCALKMSCMELARTFVFLANQGEAFHLDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDPAGNSLAGIAALEQLTQTLGRSVY
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: MATK_IRIOR
Sequence: MEELQGYLEKDGSRQQPFLYPLLFQEYIYALAHDRGFKGSLFYEPAEVFGYDSKSSLALVKRLIIRIYQQNDFLSAVHDSNKNQFVSHHHKNLGYSHFYSQMISEGFAILVEIPFSLRLVSYFEKKEIPKSHNLRSIHSIFPFLEDKLLHLNYVSDILIPHPIHMEILVQILQCWIQDVPLLHFLLFFLHKYHNWNSFLITPKKSIYVFSKENKRLFRFLYNSYVSECEFLLVFLRKQSSYLRLTSFGPFLERRHFYVKMEHLQMQHLILIVVCRDYFQGTLWSYXXXXXXXXXXXXXVILASKGTHLLMKKWKYNFVNLWQYYFHFWYQSYRIHINQLSNHSFYFLGYLSSLPRNSSTVRNQMLENSFIIDTVTKKFETIVPVIFLIGSLSKAQFCTVSGHPISKPIWADLSDSEIIERFGRMCRNLSHYHSGSSKKQGLHRIKYILRLSCARTLARKHKSTVRTFLRRLGSGLLEEFFTEEEQVLSFILPKTIPFTFYGSHKERIWYLDIIRINDLVNHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MOAA_RHOOB
Sequence: MTTVEMGIPTVRRSVSLAGRPDVDHLVDRFGRVARDLRVSITEKCSLRCTYCMPEEGLPAIPAQNLLTASEIVRLVDIAVHRLGVREVRFTGGEPLMRVDLEQMIAGCAERVPGVPLAMTTNAVGLEHRADGLARAGLTRVNVSLDSVDREHFARLTRRDRLPSVMAGIRAAARAGLAPMKINAVLMPETLSGAADLLEWCLREGVTLRFIEEMPLDADHEWARENMVTADRLLAVLGERFTLTEHGREDPSAPAEEWLVDGGPATVGIIASVTRSFCSDCDRTRLTAEGTVRSCLFSDQEIDLRSALRSGADDEELAQLWRGAMWNKWAGHGINADGFAPPQRSMGAIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: MRAY_CUPPJ
Sequence: MLLALAQWLQNDYSFLRVVNYLTFRAVMANLTALVIGLAAGPWVIRKLTELKVGQAVRTIGPQTHLVKSGTPTMGGVLVLVSIAISTVLWCDWGNRFIWVVMLVTLGYGAIGWVDDYRKVVYRDPRGMSSREKFFWQTLIGLVAAVYLAFSVSESSNVRVWDLFLSWVEGGLSLDMPYKSNLIVPFFKEVSYPLGVAGFIVLTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGGALGAFAYVMGSSVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFVMGGIFVVETVSVMLQVTWFKITKRRYGEGRRLFRMAPLHHHFELSGWKETQVTVRFWIVTMLLVLIGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KGSDH_BACSU
Sequence: MSVITEQNTYLNFINGEWVKSQSGDMVKVENPADVNDIVGYVQNSTAEDVERAVTAANEAKTAWRKLTGAERGQYLYKTADIMEQRLEEIAACATREMGKTLPEAKGETARGIAILRYYAGEGMRKTGDVIPSTDKDALMFTTRVPLGVVGVISPWNFPVAIPIWKMAPALVYGNTVVIKPATETAVTCAKIIACFEEAGLPAGVINLVTGPGSVVGQGLAEHDGVNAVTFTGSNQVGKIIGQAALARGAKYQLEMGGKNPVIVADDADLEAAAEAVITGAFRSTGQKCTATSRVIVQSGIYERFKEKLLQRTKDITIGDSLKEDVWMGPIASKNQLDNCLSYIEKGKQEGASLLIGGEKLENGKYQNGYYVQPAIFDNVTSEMTIAQEEIFGPVIALIKVDSIEEALNIANDVKFGLSASIFTENIGRMLSFIDEIDAGLVRINAESAGVELQAPFGGMKQSSSHSREQGEAAKDFFTAIKTVFVKP
What is the function of this protein?
Catalyzes the NAD(P)(+)-dependent oxidation of alpha-ketoglutaric semialdehyde (alphaKGSA) to alpha-ketoglutarate.  Prefers NADP(+) to NAD(+) as a cosubstrate.  In vitro, can also use various aldehydes.
What are the official names of this protein?
Alpha-ketoglutaric semialdehyde dehydrogenase, alphaKGSA dehydrogenase, 2,5-dioxovalerate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: FBPAP_MOOTA
Sequence: MGERITLSVIKADIGGFVGHSSVHPRLLETAERYLAESKLLIDYRVAHVGDDIDLIMTHKYGVDCPEIHHLAWNVFLQCTEVARELKLYGAGQDLLSDAFSGNVKGMGPGVAEMEFEERKSEPIIVFAADKTEPGAWNLPLYKMFADPFNTIGLVIDPKMHQGFRFEVYDLIKNERVEFSLPEELYDLLVFIGAPGRYCIKSVYSKTTGEIAAVSSTQRLNLMAGRYVGKDDPVCIVRCQSGLPAVGEALEPFANPHLVAGWMRGSHIGPLMPVGLDQSAPTRFDGPPRVVAMGFQLSGGRLVGPQDFFGDVAFDKARQTANEIASYLRSLGPFEPHRLPLEDMEYTTMPEVMAKLKNRFVKVDHRDDREPAAEELGAK
What is the function of this protein?
Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
What are the official names of this protein?
Fructose-1,6-bisphosphate aldolase/phosphatase, FBP A/P, FBP aldolase/phosphatase.
What is the protein family that this protein belongs to?
Belongs to the FBP aldolase/phosphatase family.
Protein: PYRG_MYCS2
Sequence: MPALRKHPQTATKHLFVTGGVVSSLGKGLTASSLGQLLTARGLQVTMQKLDPYLNVDPGTMNPFQHGEVFVTEDGAETDLDVGHYERFLDRNLSGSANVTTGQVYSSVIAKERRGEYLGDTVQVIPHITDEIKSRILAMAEPDAAGVRPDVVITEVGGTVGDIESLPFLEAARQVRHEVGRENCFFLHVSLVPYLAPSGELKTKPTQHSVAALRSIGITPDALILRCDRDVPEPLKNKIALMCDVDVDGVISTPDAPSIYDIPKVLHREELDAYVVRRLNLPFRDVDWTEWDDLLRRVHEPQETVRIALVGKYIDLSDAYLSVAEALRAGGFKHRAKVEMRWVASDDCETEHGAAAALSDVHGVLIPGGFGIRGIEGKIGAISYARKRGLPVLGLCLGLQCIVIEAARSVGITEANSAEFDPKTPDPVISTMADQRDAVAGEADLGGTMRLGAYPAVLTPNSVVAQAYQSTEVSERHRHRFEVNNAYRDRIAKSGLRFSGTSPDGHLVEFVEYDPQIHPFLVGTQAHPELKSRPTRPHPLFAAFIGAAIDYKAAERLPGMDLPEQFVPVEHSDADAPALEEPLEKSDVRG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: AROC_CHRSD
Sequence: MSGNTFGKLFTVTTFGESHGEALGAIVDGCPPGVALEASDLQHDLDRRRPGTSRHTTQRREPDQVRILSGVFEGVTTGTPIGLLIENTDQRSKDYSKIKDQFRPAHADYTYHHKYGIRDYRGGGRSSARETAMRVAAGAIARKFLASQGIRVRGYMSQLGPIDIAFKQWEAVDTNPFFCPDPDKLPELEAFMDQLRRDQDSVGARITVVADGVPVGLGEPVFDRLDADLAHALMSINAVKGVEIGDGFASVAQRGSEHRDEMTPQGFLSNHAGGVLGGISSGQPLIAHLALKPTSSITQPGRSIDVHGEAVEVVTKGRHDPCVGIRATPIAEAMMALTLMDHYLRHRAQNADVEVSTPRLG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: UPPP_BRUME
Sequence: MDFFNLLEAAFLGLIEGLTEFIPVSSTGHLLLIGHFLGFESTGKTFEVLIQLGAILAILSVYSAKLARIATDFPRDARTRRFVLGVLVAFLPAAVIGALAHGFIKGVLFETPMLVCIMLIVGGFILLWVDQLNLRPRYHNVMDYPLPICLAIGFIQCLAMIPGVSRSGSTIVGSLLLGADKRSAAEFSFFLAMPTMAGAFAYDLFKSRNILSFNDGALIVVGFIMAFISGVFVVRHLLDYVSRHGFALFGWWRLIVGSAGMAALIIWG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADER_BACSU
Sequence: MSKRNQARKVGRFMTMPNDPFKYSFDRLEDVADHISDVLRCPITIEDVNHKLLAYSTHSDCTDPARTSTIIGRRVPEKVINKLWKDGTIPALLKTDQPIRVKQIDEVGLSNRVAISIWKNKQVLGFIWALEIQKTLSDEDLLTLQMAAKAVKNKLLKLQIRKTKNEERSQEFFWKMLTGHIHQEDDMADGFHKLGMAAPSEFSVMIIRINGELTEKIEQQLQYLQETTQQVYVLLATVDSNELIILTSPKTDHPFQDLKQFALSTQKQLKERYKIEDVSIAFGGIYNSISFVSRSYQEALSVLKTKERFAEETKHLFSFSELGIYQYLDVLNEKRKQAGHYNYSLSKLEQYDRDHQSNMVETLERFIEADSNVNTASKLLNIHVNTLNYRLKRISQIAEIDLKNVNQKFTIYLDIKLRHMDL
What is the function of this protein?
Activates ald expression in response to alanine availability and is important for normal sporulation in B. subtilis.
What are the official names of this protein?
DNA-binding transcriptional activator AdeR, PucR-type transcriptional activator AdeR.
What is the protein family that this protein belongs to?
Belongs to the CdaR family.