PharMolix/UniProtQA huggingface dataset:
Protein: T2R39_GORGO
Sequence: MLGRCFPPDTKEKQQLRMTKLCDPAESELSPFLITLILAVLLAEYLIGIIANGFIMAIHAAEWVQNKAVSTSGRILVFLSVSRIALQSLMMLEITISSTSLSFYSEDAVYYAFKISFIFLNFCSLWFAAWLSFFYFVKIANFSYPLFLKLRWRITGLIPWLLWLSVFISFSHSMFCINIXTVYCNNSFPIHSSNSTKKTYLSEINVVGLAFFFNLGIVTPLIMFILTATLLILSLKRHTLHMGSNATGSNDPSMEAHMGAIKATSYFLILYIFNAVALFIYLSNMFDINSLWNNLCQIIMAAYPASHSILLIQDNPGLRRAWKRLQLRLHLYPKEWTL
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 39, T2R39.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PFKA_CALFI
Sequence: GGDGSLTGANRFKGEWSSLVKELLETGKITKEVAEKHSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIVEVADNIIPTAYSHQRAFVLEVMGRHCGYLALVAGIVTEADFVFAPEWPPEEDWPEKLCKKLELERQSGQRLNIIIVAEGAIDRQGNPITAEGVKKIIVDRLEMDTRTTVLGHIQ
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_PSEE4
Sequence: MKESILSDLLNRRLSLLGANLDLLKQCLHGIERECLRVTDDGRLAQTPHPEALGSALTNEQITTDYSESLLEFITPALADPAKVLDSLEEIHRFVYTKLGGEYLWSPSMPCALPAEEDIPIAEYGSSNIGKLKHVYRKGLALRYGRTMQCIAGIHYNFSLPEALWPLLRDAEGGEQNDRDYQSSAYIALIRNFRRYSWLLMYLFGASPTLDKGFLRGRPHQLEELDEQTLYLPYATSLRMSDLGYQSNAQAGLTPCYNNLASYTDSLRKAVGTPYPPYVEVGTHKDGEWVQLNTNILQIENEYYSNIRPKRVTYTGERPIQALMSRGVQYVEVRCLDINPFLPVGIDLPEARFLDAFLLFCALEESPQLDNGECGQCTDNFLTVVKEGRRPGLELRRDGQPVALKAWATELIERIGQLAGLLDRAHGGNAHAKALETQQAKVDDPELTPSAQVLARMTEHDETFVQFSLRQSRLHAEAFREQPLPAERQQAYETLARESLAEQSRLEQQEVGDFDLFVGAYQASILAISN
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: HBA1_XENBO
Sequence: MLLSADDKKHIKAIMPSIAAHGDKFGGEALYRMFLVNPKTKTYFPTFDFHHNSKQISAHGKKVVDALNEASNHLDNIAGSLSKLSDLHAYDLRVDPGNFPLLAHNILVVVAMNFPKQFDPATHKALDKFLATVSSVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1, Alpha-1-globin, Hemoglobin alpha-1 chain, Hemoglobin alpha-major chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PETL_EUCGG
Sequence: MLTITSYFGFLLAALTITSALFIGLTKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SCP1_BPSPB
Sequence: MEFKVGQDVSEIWNIHGSILPEVLMYMFPRSDESYDWEFVNDNGRHIFTAWRKSEPIPTLEEIEKAAIELEEKKNAPKPKTLEERVADLEKQVAYLTSKVEGTN
What are the official names of this protein?
Stress response protein SCP1.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: KAD_CHLP8
Sequence: MRVILLGAPGAGKGTQAQYISEAFDIPQISTGDMLRAAVKAQSELGMAAKKVMDEGGLVPDDIIIGLVKERIEEDDCANGCLFDGFPRTIAQADALRTEGIRIDNIIEIDVPDEEIIKRMSGRRVHPASGRTYHIVFNPPAVEGKDDVTGEDLVQRDDDTEETVRKRLKVYHDQTEPLVGYYRNLAIEGSDDAPKYSCINGIGQVEQIKQDIIAALKQ
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP42_SCHPO
Sequence: MTALMNHIYIDNPLISNSTNNVTHELLIDLHELYNDGEISRIVLLRTLVTQSADDATWIINLTDDVLNGLPLLKKRDRYTTQCHSTNMASTYDCDTGANAVGARGGATLAADYRGDWGG
What are the official names of this protein?
Uncharacterized protein CPT2R1.02.
Protein: RL10_ACICJ
Sequence: MDRAQKREFVDQLAAVFAETSMVVVSRNDGLTVADVTALRVKMREAGAQYKVAKNRLAHLALEGTRFDGLKPMLKGPTALAWSQDPVAVAKVAVEFAKTNEKFVLVGGALGTQMLDASGVKALAELPSLDQLRAKLLGLIQAPATKVAGVLQAPAGQLARVFAAYARADEADAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MURQ_PSEA6
Sequence: MTQVNLLSELNSIASEGRNIDTLDIDTLPTLAILEKINQEDHKVAAAVSAAMADITSGVEAIVSSFNRGGRLVYMGAGTSGRLGILDAVECMPTFSVPEGMVIGLIAGGEKAVIHAVEGAEDDRAMGVADLKALNFSDKDTLVGIAASGRTPYVAAGLEYAKQCKATTIAVNCSPNSVIGQIADIDICAQVGPEVLTGSTRLKSGTAQKLILNMLSTASMIRIGKTYQNLMVDLNASNQKLYARAVRIVMQATDCEEQTAYEALDHANKEVKVAILMILTGVDVQQAREKLAQKQGFLRHAMSQGES
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: UGPB_BRUAB
Sequence: MFTRLITTSVLTGAIALTIGSQAFAQTELAWWHGMTGANNEMVNELSKEFNESQSEYKIVPVYKGNYPETLNAGIAAFRSKQPPAILQVFDAGSGVMMAAEGAIVPAAEVLEKGGYKFDKSQYLPGIVAYYSKPDGTMLSFPYNSSSPILYYNKDAFKKAGLDENKPPKTWPEVFEAAKKIKASGASPCGFTSTWLTWIQTENFAAWNNVPYGTNENGLAGTDVKLEINSPLYVEHFQAIADLAKDGTFRYGGRTSEAKQLFTSGECAMLTESSGGLGDVVKSGINYGIGQLPYYEGHGPQNTIPGGASLWVFAGLSDDQYKGIAEFFNFLSQTKIQVKLHEKSGYLPVTLAAYEETKKSDFYEKNPGRETPILQMMGKEPTENSKGVRLVNLPQVRDILNEEFEAMLGGKQDAKTALDNAVKRGNAAIAAAQ
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Binds G3P.
What are the official names of this protein?
sn-glycerol-3-phosphate-binding periplasmic protein UgpB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL21_RHOPS
Sequence: MFAVIKTGGRQYRVVPDDVLEVGKIEGEVGTIVQLGEVLMLGGDTPQLGLPTIAGASVAAEVLDHKRGPKVISFKKRRRKNSKRKRGYRDEITVLRITEILADGKKPSVGPRPKRVKAEPAPAADAAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PYRDB_ENTFO
Sequence: MMKNPLAVSIPGLTLKNPIIPASGCFGFGEEYANYYDLDQLGSIMIKATTPQARYGNPTPRVAETPSGMLNAIGLQNPGLDVVMQEKLPKLEKYPNLPIIANVAGACEEDYVAVCAKIGQAPNVKAIELNISCPNVKHGGIAFGTDPEVAFQLTQAVKKVASVPIYVKLSPNVTDIVPIAQAIEAGGADGFSMINTLLGMRIDLKTRKPILANQTGGLSGPAIKPVAIRLIRQVASVSQLPIIGMGGVQTVDDVLEMFMAGASAVGVGTANFTDPYICPKLIDGLPKRMEELGIESLEQLIKEVREGQQNAR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_CAMHC
Sequence: MLKDDMLEVALLGKTIGLKGAIKLHNRSDFPSQFKKGAKFYLTDGEILEILSFNKTNFVAVFKNYENIECAAKLTNKILYQSKEITKKTCKLGKDEFFYFEILGLEVFENEEKLGKVADIFEAGNFVFEIATDEKLIKKGFPKIFYLPYTDHFIDKISIEEGKIFSRFGFEILQNS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_BRUSI
Sequence: MNWITNYVRPKINSMLGRREMPENLWIKDPSTGEMVFHKDLESNQFVIPSSGHHMRIKAKDRLRFFFDNGEYTTLEAPKVPLDPLKFRDEKKYIDRLKDYRSRTGMDDAIVNGLGTIEGLPIVATVQDFSFMGGSLGMGAGEAIIQGFEKAIELKRPLVLFASSGGARMQEGILSLMQLPRTTVAVEMLKEAGLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGALIGFAGPRVIEQTIREKLPEGFQSSEYLMEHGMVDMVVSRLELKATIARLLKIMTKQPANSDAPAPQKPDADSKAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_PSEAB
Sequence: MVDKLTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLARKAFFPGKLPFPVMHVDTRWKFQEMYRFRDRMVEEMGLDLITHVNPDGVAQGINPFTHGSAKHTDVMKTEGLKQALDKYGFDAAFGGARRDEEKSRAKERVYSFRDSKHRWDPKNQRPELWNIYNGKVKKGESIRVFPLSNWTELDIWQYIYLEGIPIVPLYFAAEREVIEKNGTLIMIDDERILEHLSDEEKARIEKRMVRFRTLGCYPLTGAVESSATTLPEIIQEMLLTRTSERQGRVIDHDQAGSMEEKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: SYDND_RHILO
Sequence: MHRYRSHTCAQLRKSDVGSSVRLSGWVHRVRDHGGLLFIDLRDHYGLTQIVADPDSPAFKVAETVRGEWVIRVDGEVKARLSETVNANLPTGEIEIFAREIEVLSAAKELPLPVFGEPDYPEDIRLKYRFLDLRRDTLHKNIVARTKIIAEMRKRMGDVGFTEFSTPILTASSPEGARDFLVPSRIHPGTFYALPQAPQQYKQLIMVSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLEMSFVEQDDVLNTMEPVLRGVFETFANGKPVTQKFQRIPYDVAMRKYGSDKPDLRNPIEMQAVSDHFRDSGFKVFANILANDPKAEVWGIPAKTGGSRAFCDRMNSWAQGEGQPGLGYIFWRKEGDKLEGAGPLAKNIGEERTEAIRQQLGLADGDAAFFVAGDPKKFVSFAGAARTRAGEELNLVDRERFELCWIVDFPFFEWNEEEKKIDFAHNPFSMPQGGIDALNGEDLLGIKAFQYDMVCNGFEIASGGIRNHLPETMVKAFETVGLDRATVEERFGGLYRAFQYGAPPHGGMAAGIDRVVMLLVGAKNLREVTMFPMNQQAYDLLMNAPSEASPQQLRELALRVAPTKKDA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACG_STRP8
Sequence: MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWYTAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGDVNPKGVEYYHNLFAECHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNEIGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDGGYSGEIGVVHALPTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDLREEDFVALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRRKAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDDGRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERYPKKSAYWYKKVAETQVIE
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: NU4M_PATPE
Sequence: MIYLILTSTLTLATTWIVPRNLLWPSSILNSILISVISLNLLNNHSTSLWHNLSLNFATDPTSTPLIILSSWLVPISLIASINTIQNHNHINQRTFISLVFTILTALILTFSSLELSLFYIAFETTLLPTLTLISRWGAQKERYQASIYFLFYTLIGSLPLLVSIIAIFSYENTIILPSIHLTNYITSLPITLTSIWWIFCFIAFIIKMPIYGFHLWLPKAHVEAPIAGSMILAAILLKLGGYGLLRTIPLFYTPSSLLLSPPATAFCIWGALITSIICLRQTDLKALIAYSSVGHMSIVASGIFSLSLWGINGALTLMIAHGLISSALFCLANLLYERNGTRTLSITRGFKMVTPLLTLWWTITCVANLGLPPTPNLIGELLILVAIIDWNTLSAPIITMATVFGAIYSLLILSSTNNSSFPQFLSNIQPTNTSEHTLITFHLIPLVFLILNPSAILIG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TBB8_HUMAN
Sequence: MREIVLTQIGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVYYNEASGGRYVPRAVLVDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGAELMESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGRYLTAAAIFRGRMPMREVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRGLKMSATFIGNNTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDEEYAEEEVA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.  TUBB8 has a key role in meiotic spindle assembly and oocyte maturation (PubMed:26789871, PubMed:34509376).
What are the official names of this protein?
Tubulin beta-8 chain, Tubulin beta 8 class VIII.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Protein: ARHGP_MOUSE
Sequence: MKPPDRPTPGRTDRILGVMGGMLRACAVPGQEGPPERDPLGPGSTKTESDCIEEDQTGQREPEVLAWAPQPESYSIAVSEGSMSASAVSGLAALSGPSSGLSSDPCSPIPPGPVTGLRRWLDHSKHCLSVETEAESGQTGQCENWTLGPTLTTGQELPELTLLTTLLEGPGDKAQPAEEETLSQAPKNEEEQKKMALERSMFVLGELVETERTYEDDLGQIVEGYMATMATQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQQCLKDPDWLAQLFIKHERRLHMYVVYCQNKPKSEHVLSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYRRAGKDTEELEQAVEVMCFVPKRCNDMMSLGRLRGFEGKLTAQGKLLGQDTFLVTEPEAGGLLSSRGRERRVFLFEQIIIFSEALGGGGRGGAQPGYVYKNSIKVSCLGLEGNLQGNPCRFALTSRGPEGGIQRYVLQASDPAVSQAWIKQVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPGGPWVGSPGRMRPGDLAQASMHTPINGSLPSLLLLPRGEVSRVLLPLDTQALSDTPQTPHDSPALPTVNTPPCQARLAKLDEDEL
What is the function of this protein?
May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers.  It works as a guanine nucleotide exchange factor for Rho family of small GTPases.  Links specifically G alpha q/11-coupled receptors to RHOA activation (By similarity).  May be an important regulator of processes involved in axon and dendrite formation.  In neurons seems to be an exchange factor primarily for RAC1.  Involved in skeletal myogenesis.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 25, Guanine nucleotide exchange factor GEFT, Rac/Cdc42/Rho exchange factor GEFT, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT, p63RhoGEF.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cell membrane. Cytoplasm, myofibril. Note=Highly colocalizes with actin regions.
Protein: CH10_STRP8
Sequence: MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSETGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSP2_PROFL
Sequence: MVLIRVLANLLILQLFYAQKSSELIIGGDECNINEHRFLVALYTFRSRRLHCGGILINQEWVLSAARCNRKNIRIQLGMHSTNVINEDVQTRVPKEKFFCLSSKTHTRWNKDIMLIRLNSPVNNSTHIAPVSLPSNPPSLGSVCRVMGWGTISATKETHPDVPHCANINILDYSVCRAAYARLPATSRTLCAGILEGGKDSCKADSGGPLICNGEIQGIVSRGGHSCGQPRKPGLYTKVFDHLDWIKSIIAGNKDAICPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease 2, SVSP 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_POLNS
Sequence: MKPSMRAKLDHLDTRLAELNSLLTSEEATKDMDAYRKLTREHSDIATVVEQFYLYKQAEADAQAAEEMRKDPEMKEFADEEQKQALATMEALESTLQKLLLPKDENDERNVFLEIRAGTGGDEGALFAGDLLRMYTRFAERQGWKVEVVSAAESDLGGYKEVVLRLVGQAVYSRLKFESGGHRVQRVPQTETQGRIHTSACTVAVMPETDELEAVKINPAELRIDTFRASGAGGQHINKTDSAIRITHLPTGTVVECQDDRSQHRNREQAMKVLVSRIMDAREREKHQLEAQTRKSLVGTGDRSDRIRTYNFPQGRITDHRINLTLYKIDAMMDGDIDDLCNALASEHQAELLAALGDN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APCB_THEVB
Sequence: MQDAITAVINASDVQGKYLDTAAMEKLKAYFATGELRVRAASVISANAANIVKEAVAKSLLYSDITRPGGNMYTTRRYAACIRDLDYYLRYATYAMLAGDPSILDERVLNGLKETYNSLGVPIAATVQAIQAMKEVTASLVGADAGKEMGIYFDYICSGLS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Protein: TPPC3_DICDI
Sequence: MSKKYDKLGNDVFNKVEKINSELFTLTYGALVTQLIKDYEDIEQVNIKLEQMGYNIGIRLIEEFLAKSGIGRCSDFIETAEVIAKVGFKMFLGVNAHVGDWDANRKEFHLTIEDNPLIDFVELPDQYKHKLYYSNILCGVMRGALEMVQMKVKCTFVKCTLSDDSTSEIKVVLEEVLSDMIPVGYD
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: S10A1_BOVIN
Sequence: MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDADAVDKVMKELDENGDGEVDFQEYVVLVAALTVACNNFFWENS
What is the function of this protein?
Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation.  In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers conformational changes.  These changes allow interactions with specific target proteins and modulate their activity.  Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca(2+) cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca(2+)-ATPase/ATP2A2 and mitochondrial F1-ATPase.  Facilitates diastolic Ca(2+) dissociation and myofilament mechanics in order to improve relaxation during diastole.
What are the official names of this protein?
Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cytoplasm. Sarcoplasmic reticulum. Mitochondrion.
Protein: RS17_CYTH3
Sequence: MEEILRNARKERTGKVVSNKMNKSITVAVERKVKHAKYGKFIHKTTKLMAHDENQECGIGDTVRVMETRPLSKLKRWRLVEVIEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DNCH_RIPO1
Sequence: MNDYTRTIRLSDTDAAGVVYFASLLSICHEAYEASLEASGIDLKSFFRDSEVVIPIVHAEIDFFRPLYSGDRIIITLTTLQLKDTEFEITYQVGLVAPQSSLIAKAKTRHVAINPQTRQRTPLSESLMQWLKSTENSE
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.