PharMolix/UniProtQA huggingface dataset:
Protein: PPSA_SYNY3
Sequence: MVSSVVEKTSVAHKETALILWFEEVGTHDVGLVGGKNSSLGEMIQQLTNKGVNVPSGFATTAYAYRYFIQEAGLEQKLRDLFTDLDVNDMANLQERGHLARQLILDTPFPQNLQTAIAEAYGAMCERYGQKMGRTGVDVAVRSSATAEDLPEASFAGQQETYLNVHSLSCVLESCHKCFASLFTDRAISYRHHNGFDHFAVALSVGVQKMVRSDLATSGVMFSIDTETGFKNAALITAAYGLGENVVQGAVNPDEYFVFKPTLKEGFKPILEKRLGSKAIKMVYDVGGSKLTKNVEVAEPEREKYCINDEEILQLARWACIIEDHYSGVRGVYTPMDIEWAKDGQTGELFIVQARPETVQSQKSANVIKTYELKDHSQVLATGRSVGAAIGQGKAQVIRNVSQINQFRPGEVLITNRTDPDWEPIMKQASAIVTNQGGKTCHAAIIAREMGIPAIVGCGDATDTIKTGEDVTICCSEGDEGSVYSGILNYEVHETELSNLPRTKTQILMNVGNPEQAFGFASYPADGVGLARLEFIIANHIKAHPLALMKFDELEDPLAKAEIAELTKLYAGDRPRFFVDKLAHGIAMIAAAFYPKPVVVRMSDFKSNEYANLLGGRQFEPKEENPMIGWRGASRYYDPNYREAYALECQALKRVRDEMGLTNVIPMIPFCRTPDEGRKVIAEMAKHGLKQGKNGLEIYVMCELPSNVILADEFSEVFDGFSIGSNDLTQLTLGLDRDSSLVAHLFDERNLGVKRMVKMAIETAKANGRKIGICGQAPSDYPEFAEFLVELGIDSISLNPDSVLKTVLRIAEVEKALG
What is the function of this protein?
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
What are the official names of this protein?
Phosphoenolpyruvate synthase, PEP synthase, Pyruvate, water dikinase.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: FLS2_ARATH
Sequence: MKLLSKTFLILTLTFFFFGIALAKQSFEPEIEALKSFKNGISNDPLGVLSDWTIIGSLRHCNWTGITCDSTGHVVSVSLLEKQLEGVLSPAIANLTYLQVLDLTSNSFTGKIPAEIGKLTELNQLILYLNYFSGSIPSGIWELKNIFYLDLRNNLLSGDVPEEICKTSSLVLIGFDYNNLTGKIPECLGDLVHLQMFVAAGNHLTGSIPVSIGTLANLTDLDLSGNQLTGKIPRDFGNLLNLQSLVLTENLLEGDIPAEIGNCSSLVQLELYDNQLTGKIPAELGNLVQLQALRIYKNKLTSSIPSSLFRLTQLTHLGLSENHLVGPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNLTVLTVGFNNISGELPADLGLLTNLRNLSAHDNLLTGPIPSSISNCTGLKLLDLSHNQMTGEIPRGFGRMNLTFISIGRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLKPLIGKLQKLRILQVSYNSLTGPIPREIGNLKDLNILYLHSNGFTGRIPREMSNLTLLQGLRMYSNDLEGPIPEEMFDMKLLSVLDLSNNKFSGQIPALFSKLESLTYLSLQGNKFNGSIPASLKSLSLLNTFDISDNLLTGTIPGELLASLKNMQLYLNFSNNLLTGTIPKELGKLEMVQEIDLSNNLFSGSIPRSLQACKNVFTLDFSQNNLSGHIPDEVFQGMDMIISLNLSRNSFSGEIPQSFGNMTHLVSLDLSSNNLTGEIPESLANLSTLKHLKLASNNLKGHVPESGVFKNINASDLMGNTDLCGSKKPLKPCTIKQKSSHFSKRTRVILIILGSAAALLLVLLLVLILTCCKKKEKKIENSSESSLPDLDSALKLKRFEPKELEQATDSFNSANIIGSSSLSTVYKGQLEDGTVIAVKVLNLKEFSAESDKWFYTEAKTLSQLKHRNLVKILGFAWESGKTKALVLPFMENGNLEDTIHGSAAPIGSLLEKIDLCVHIASGIDYLHSGYGFPIVHCDLKPANILLDSDRVAHVSDFGTARILGFREDGSTTASTSAFEGTIGYLAPEFAYMRKVTTKADVFSFGIIMMELMTKQRPTSLNDEDSQDMTLRQLVEKSIGNGRKGMVRVLDMELGDSIVSLKQEEAIEDFLKLCLFCTSSRPEDRPDMNEILTHLMKLRGKANSFREDRNEDREV
What is the function of this protein?
Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs).  Flagellin-binding to the receptor is the first step to initiate the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6), resulting in enhanced resistance against pathogens.  Binding to the effector AvrPto1 or to the phosphatase hopD2 from Pseudomonas syringae blocks the downstream plant immune response.
What are the official names of this protein?
LRR receptor-like serine/threonine-protein kinase FLS2, Protein FLAGELLIN-SENSING 2, Protein FLAGELLIN-SENSITIVE 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Note=Internalization by endocytosis, especially in response to pathogen-associated molecular patterns (PAMPs e.g. flg22) recognition (PubMed:24923602, Ref.32). Accumulates at the plasma membrane, in an ACD6-dependent manner, in response to salicylic acid (SA) signaling, thus priming defenses (PubMed:24923602).
Protein: ESFL9_ARATH
Sequence: MSSSRFLILCIILISFFPLHECENGKSVESNKAMKPVCMPVNCNNKDKKLTCACCIGANPRNRCYNSRSQCTADCKL
What are the official names of this protein?
EMBRYO SURROUNDING FACTOR 1-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the MEG family.
Protein: PMEI9_ARATH
Sequence: MELKNTIFLVILLSITILQSSSATPNRSESDQFIVSSCQTTQYPSLCVHTLSAYATKIRHNNDQDLAQTALIISLARAKSVTIFVAKLTKETPKFKRREYLAIKDCIEVLGNSVDRLAQSVKELARAGHAVASEDFMWKMSNVQTWVSAALTDETTCLDGFSERAMGGKVKRLIRYKVVHVAQVTSNALALVNQFAEKRSVKFP
What is the function of this protein?
Pectin methylesterase (PME) inhibitor that probably targets root-expressed PME, regulates de-methylesterification of pectins in roots and affects root growth.
What are the official names of this protein?
Pectinesterase inhibitor 9, Pectin methylesterase inhibitor 9, AtPMEI9.
What is the protein family that this protein belongs to?
Belongs to the PMEI family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RS14Z_CAMC1
Sequence: MAKKSMIAKAARKPKFAVRGYTRCQICGRPHSVYKDFGICRVCLRKMANEGLIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RL6_BACFN
Sequence: MSRIGKLPISIPAGVTVTLKDDVVTVKGPKGELSQYVNPAINVAIEDGHITLTENENAMLDNPKQKHAFHGLYRSLVHNMVVGVSEGYKKELELVGVGYRASNQGNIIELALGYTHNIFIQLPPEVKVETKSERNKNPLILLESCDKQLLGQVCSKIRSFRKPEPYKGKGIKFVGEEIRRKSGKSAGAK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ZC3H4_HUMAN
Sequence: MEAAPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDREDGELEEGELEDDGAEETQDTSGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPSHATPLPKKAYSKMDSKSYGMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRGRGKGMGRGRGRGGSRGGMNKGGMNDDEDFYDEDMGDGGGGSYRSRDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHADMHADMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLLGDAEDYGHYEELPGEPGEHLFPEHPLEPDSFSEGGPPGRPKPGAGVPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPPASVGELSSSGLGDPRLQKGHPTGSRLADPRLSRDPRLTRHVEASGGSGPGDSGPSDPRLARALPTSKPEGSLHSSPVGPSSSKGSGPPPTEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPAALQSMPTLDPRLHRAATAGPPNARQRPGASTDSSTQGANLPDFELLSRILKTVNATGSSAAPGSSDKPSDPRVRKAPTDPRLQKPTDSTASSRAAKPGPAEAPSPTASPSGDASPPATAPYDPRVLAAGGLGQGGGGGQSSVLSGISLYDPRTPNAGGKATEPAADTGAQPKGAEGNGKSSASKAKEPPFVRKSALEQPETGKAGADGGTPTDRYNSYNRPRPKAAAAPAATTATPPPEGAPPQPGVHNLPVPTLFGTVKQTPKTGSGSPFAGNSPAREGEQDAASLKDVFKGFDPTASPFCQ
What is the function of this protein?
RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs) (PubMed:33913806, PubMed:33767452).  LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein (PubMed:33913806, PubMed:33767452).  Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome (PubMed:33913806, PubMed:33767452).  The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs (PubMed:33767452).
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the suppressor of sable family.
Protein: ATP78_ECOLX
Sequence: MTKQYERKAKGGNLLSAFELYQRNTDNMPGLGEMLVDEWFETCRDYIQDGHVDESGTFRPDNAFYLRRLTLKDFRRFSLLEIKFEEDLTVIIGNNGKGKTSILYAIAKTLSWFVANILKEGGSGQRLSELTDIKNDAENRYADVSSTFFFGKGLKSVPIRLSRSALGTAERRDSEVKPARDLADIWRVINEAKTINLPTFALYNVERSQPFNRNTKDNAGRREERFDAYSQALGGAGRFDHFVEWYIYLHKRTISDISSSIKELEQQVNDLQRSVDGGMVSVKSLLEQMKLKLSEASERNDAAVSSKMVTESVQKSIVEKSICSVVPSISKIWVEMTTGSDLVKVTNDGHDVTIDQLSDGQRVFLSLVADLARRMVMLNPLLENPLEGRGIVLIDEIELHLHPKWQQEVILNLRSVFPNIQFIITTHSPIVLSTIEKRCIREFDPNDDGNQSFLDSPDMQTKGSENAQILEQVMNVHPTPPGIAESHWLGDFELLLLDNSGELDNQSQELYDKIKTHFGIDSAELKKADSLIRINKMKNKINKIRAEKGK
What is the function of this protein?
Probable ATPase component of antiviral defense system retron Ec78, composed of a non-coding RNA (ncRNA), a reverse transcriptase (RT), this protein and a putative HNH endonuclease.  Expression of retron Ec78 confers protection against bacteriophage T5.  At multiplicity of infection (MOI) of 0. 02 cultures slow growth when infected with T5 but do not collapse, at MOI 2 cultures enter growth stasis.
What are the official names of this protein?
Retron Ec78 probable ATPase.
Protein: SYC_ACIB3
Sequence: MQPFVLYNSEQRKKVEFVPRKEGHIDMYVCGMTVYDYCHIGHARVMVAFDYIIRFLRSQGWKVRYIRNITDIDDKIIKRANENGETIQQLTTRFIDAMNEDAANLGCLAPDEAPKATEYIDQMQNMIGNLVNKGAAYPASNGDVYFEVTKFEKYGRLSGRKLDDMQAGASERIDVEVEKKHPFDFVLWKHAKENEPSWASPWGNGRPGWHIECSAMSTCCLGNHFDIHGGGSDLMFPHHENEIAQSEASTGEQYVNYWMHVGFINVDGEKMSKSLGNFFTIRDVMEKFHPEVIRYFIVSSHYRSPVNFSDVALKEAKTSLTRFYHSFKAYQQVYGQTTTEALDQSFIERFNNAMCDDFNTAEAMAVLFELNKELNRAVKEEQADQATVLYSTLRHLTNILGLVQHNVDDFLKSDIGQDALALSDAEIEDFIQQRVDAKKAKDFAKADSIRQSLLEQGVVLEDTRQGTVWRRAD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERO1A_MOUSE
Sequence: MGRAWGLLVGLLGVVWLLRLGHGEERRPETAAQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLKKPCPFWNDINQCGRRDCAVKPCHSDEVPDGIKSASYKYSEEANRIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDSFCEIDDIQSPDAEYVDLLLNPERYTGYKGPDAWRIWSVIYEENCFKPQTIQRPLASGRGKSKENTFYNWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDTWLEKKWGHNVTEFQQRFDGILTEGEGPRRLRNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDAENKALLLEILHEIKSFPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFQLTRQEIVSLFNAFGRISTSVRELENFRHLLQNVH
What is the function of this protein?
Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum.  Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation.  Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell.  Required for the proper folding of immunoglobulins (By similarity).  Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.
What are the official names of this protein?
ERO1-like protein alpha, ERO1-L, ERO1-L-alpha, Endoplasmic reticulum oxidoreductase alpha, Endoplasmic reticulum oxidoreductin-1-like protein, Oxidoreductin-1-L-alpha.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Golgi apparatus lumen. Secreted. Cell projection, dendrite. Note=The association with ERP44 is essential for its retention in the endoplasmic reticulum (By similarity). In neurons, it localizes to dendrites (By similarity).
Protein: RS2_PYRFU
Sequence: MADEYLVPLDQYLAAGVHIGTQQKTKDMKKFIYRVRQDGLYVLDVRKTDERLKVAGKFLAKFEPQSILAVSVRLYGQKPVKKFGEVTGARAIPGRFLPGTMTNPAVKNFFEPDVLIVTDPRADHQAMREAVEIGIPIVALVDTENLLSYVDLAIPTNNKGRKALALIYWILAREILYNRGEIQSREDFKIPVEEFEMKIVRR
What are the official names of this protein?
30S ribosomal protein S2, Small ribosomal subunit protein uS2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: HSLO_CLOPE
Sequence: MSDKLIRAIAKDGMIRIFATETTELVDEASKIHDCTPTAAAALGRMLTAGTMMGAMLKSDKEVVTLQINGGGMAKGVTVTAYSDCSVKGYIGNPHVDLPLNTENGKLNVGEAIGKNGGLTVIKDLGLKDPYVGQVPIYSGEIAEDLAYYFTASEQIPSAVALGVLVDRDHSIKKAGGFIIQLLPGADELLGDLLTYRLDEIPSLTTMLSEGKTIEEVIEFIFDGMDLKILEEETPKYKCDCSREKVERALLSIGYKDLKELYDEGKEEELKCHFCNKAYKFTKEDIGKLLEEKEKSIADEVSEEMKKAEEKEKEEKNKK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EASF_CLAFS
Sequence: MPACSVTDIRSHVVEDSLPDQVIKGLKSSPKTLPALLFYSNEGLDHWNHHVSQPDFYPRHQEVDILKQRGDEMARAIAPNSVILDLGSANLEKVVHLLKALEAQGKDVTYFALDISAPQLEVTLNEIPTSEFRHVRFAGLHGTFEDGLRWISETPHICDLPHCVLLLGLTIGNFSRASAATFLGNIASQALRGASKDQSSILMSLDSCKVPTQILRAYTSNGVEPFALQSLTFAKTLLRGPMLHNDSDEPLPCYLQPDDWYYHSEWNFVLGRHEASLIPRYRDVHLGSLLQDITVKKDEKIRFGCSYKYDDMERHQLFLDAGVEQDVAWTNEGCDVVIYELKKRSNTEKLGIDRN
What is the function of this protein?
4-dimethylallyltryptophan N-methyltransferase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:17720822).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (By similarity).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (By similarity).  Agroclavine dehydrogenase easG then mediates the conversion of chanoclavine-I aldehyde to agroclavine via a non-enzymatic adduct reaction: the substrate is an iminium intermediate that is formed spontaneously from chanoclavine-I aldehyde in the presence of glutathione (By similarity).  Further conversion of agroclavine to paspalic acid is a two-step process involving oxidation of agroclavine to elymoclavine and of elymoclavine to paspalic acid, the second step being performed by the elymoclavine oxidase cloA (PubMed:17720822).  However, cloA does not encode a functional enzyme indicating that C. fusiformis terminates its ergot alkaloid pathway at elymoclavine (PubMed:17720822).
What are the official names of this protein?
4-dimethylallyltryptophan N-methyltransferase easF, 4-dimethylallyltryptophan methyltransferase, Ergot alkaloid synthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: KGUA_SALPA
Sequence: MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAPRPGEVHGEHYFFVNHDEFKTMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALSDLKTIIRAERLRMSRQKQRHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNAT1_ARATH
Sequence: MFLGGTISTPPASLRLRSTLNPQNAVTQSSSQATFPAAMQRKPPSYSISDEDLESRGFLLRRTTEGLNLDQLNSVFAAVGFPRRDTAKIEVALQHTDALLWVEYEKTRRPVAFARATGDGVFNAIIWDVVVDPSFQSCGLGKAVMERLIEDLQVKGICNIALYSEPRVLGFYRPLGFVSDPDGIKGMVFIRKQRNKK
What is the function of this protein?
Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA) and epsilon-lysine acetylation (KA), possibly with a low efficiency or toward specific plastid substrates (PubMed:32633465).  Involved in melatonin biosynthesis by catalyzing the formation of N-acetylserotonin (NAS) from serotonin and of melatonin (N-acetyl-5-methoxytryptamine) from 5-methoxytryptamine (5-MT) (PubMed:31698875).
What are the official names of this protein?
GCN5-related N-acetyltransferase 1, chloroplastic, Serotonin N-acetyl transferase 2, AtSNAT2.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: AROE_PSYCK
Sequence: MTQHFIVIGNPIAHSKSPEIHTLFGTQAGLDICYQRQYCPDDAASFTAVIEAFFHGGGVGANVTVPFKQIAYECCAARGGLSEHAKVAGAVNTLLLNKALLAKGVPPVEALFGDNTDGQGLVNHMQRLGWPLNGARVAIIGAGGAARGVVLPLIEAGIETLSIANRTVSKAEILVDELSTASEKINQHTIQTYATADLSGDFDIIINATSIGLSGETLPLTDKLNCQYAYDMMYGRELPFLQHFSIRGAQTSDGYGMLIGQAALSFERWTGRAIDVAQATTALENVST
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: 5MAT1_SALSN
Sequence: MTTTTTILETCHIPPPPAANDLSIPLSFFDIKWLHYHPVRRLLFYHHPSSKSQFLHTIVPHLKQSLSLALTHYLPVAGNLLYPSNTEKFPQLRYAAGDSVPVTIAESNSDFESLTGNHTRDADQFYDLLPPIPPIEEESDWKLINIFAVQITLFPGEGICIGFSNHHCLGDARSIVGFISAWGEINGIGGYEGFLSNHSDSLSLPIFDRSFINDPNKIDAIFWKVLRNIPLKTASFPLPTNRVRSTFLLRRSDIEKLKTATKSPASSFVAAAAFVWSCMVKSGDKSDENAPELFIIPADARGRVDPPIPENYFGNCIVSSVAQVERGKLAAEDGFAVAAEAIGGEIEGKLKNRDEILRGAENWMSDIFKCFGMSVLGVSGSPKFDLLKADFGWGKARKLEVLSIDGENHSMSLCSSSDFNGGLEVGLSLPRERMAAFEEVFRASIMAASGPARRSPALVEPL
What is the function of this protein?
Catalyzes the transfer of a malonyl group from malonyl-CoA to the 6'''-hydroxyl group of the 5-glucosyl moiety of anthocyanins.  Active towards bisdemalonylsalvianin (pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside) and shisonin, but not towards nodemalonylsalvianin, salvianin, pelargonidin 3,5-diglucoside and delphinidin 3,5-diglucoside.
What are the official names of this protein?
Malonyl-coenzyme:anthocyanin 5-O-glucoside-6'''-O-malonyltransferase, Malonyl CoA:anthocyanin 5-O-glucoside-6'''-O-malonyltransferase, Ss5MaT1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: LPXK_LEGPL
Sequence: MSFFVNRVWYGNHFLQWILVPFSWLYRIVIRTRRWYLQRFCQQLYPIPIIVVGNVTVGGVGKTPLVIEIAKKIQQKGLKVGIVSRGYKAAIKHFPYEVKLNDSAELVGDEPLMMARKINCPVVIAPKRNEAVRYLLDKHSVEIIISDDGLQHYKMGRSIEIVVIDGMRKLGNGFCLPAGPLREPDSRLKQVDFVIVNQGAAGGAYSMELIPKNIVRLSTQEEVSKDSFTSEVAAVAGIGNPQRFYSTLSQLGIKFNPYSYPDHHQFKPHDLNDIDLPVIMTEKDAVKCYSFSSDKLYYLPVEAKLNDSFWEAFWSHQQLQGYY
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: METAS_SHEAM
Sequence: MPVKIPDNLPAAEILSAENIFVMSETRAAHQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESRHTSLDHMNTFYRDFEDVRHKNYDGLIITGAPLGQLDFEEVTYWDHIREIIDWSQSHVTSVLFLCWAAHAGLYHLYGLKRELLKTKRSGVFVHSRSCDHHPLLRGFDEEFFAPHSRYAEIPVAQIHAHPALQVLAESDEAGAYLVLSRNSRNLFVIGHPEYQKSTLSDEYHRDLAAGINPEIPQNYFRNDDPAQPPVARWHSHGSLLVSNWLNYYVYQLTPYDLSDMSAITPWEASSKS
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZP3R_RAT
Sequence: MTAWSLHELWKTSHSTLFQVTLATVLMAPVLGDCGPPPSLPFASPISQLDEVSFPPGAVLKYTCHHGFKRTNSSHITCDENGSWVYTTFCARKRCKNPGELVNGKIEILSDLLVGLNIEFSCSEGYLLIGSATSRCEVQGKGVNWSDSLPECVIATCEPPPVINNGKHSGREEDLYTYGSMVIYSCDPSYTLFGNASIVCTVVNKTVGVWSPHPPACEKIVCHQPQIPKGELVPGFRHFHTYKDALEIRCKKGFALRGNSVIHCEANGEWFPSVPTCEPNGCIDIPDISYASWDGNRFPLENTAVFEIGTKLKYRCKPGYRANVHDVQIVTCQENLTWSSPSGCERVCCPTPNMEKIKIVSERRDFTGTCVYAYGDYVFYICSEGTYPMTTDGRSSCQADGKWDPAIPSCEADPSLQNHFALTFPNISETNVTNRTYLLENENATESFIKAVCPKPEIINGNLSVEKEIYAEMENITIQCDSGYDLVGSSNIICLENRTWYPDIPFCIMEGPEDCEIVNKGRQLLQCLSSPEDVQRALEVYKLSLEIERLEQQREKRTSVHRKAHYTKVDGPFRPFS
What is the function of this protein?
Binds to ZP3 glycoprotein in egg zona pellucida.  Probably involved in interactions between sperm acrosome and egg zona pellucida during and immediately following the acrosome reaction (By similarity).
What are the official names of this protein?
Zona pellucida sperm-binding protein 3 receptor, Sperm fertilization protein 56, sp56.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome lumen. Note=Sperm acrosomal matrix.
Protein: KUP1_LACLA
Sequence: MGYESNRSFNKATGAGFIIAMGIVYGDIGTSPLYTMESIVQGQGGLERISETSIIGALSLIIWTLTLITTVKYVWIALKADNNHEGGIFSLFTLVRKYAKWLIIPAMIGGAALLSDGALTPAVTVTSAIEGLRSIPAFHEAFGQQQLPIVIITLAILAVLFLIQRFGTSIVGKVFGPVMFIWFSFLGITGLINLFGDFSVLQAINPYWAIHLLLSPENKAGIFVLGSVFLATTGAEALYSDLGHVGRGNIHVSWPFVKVCIILSYCGQGAWLLQNRGKSLGDINPFFAVLPQNLIIFSVILATLAAIIASQALISGSFTLVSEAIRLKLLPRLRIFYPGETFGQLYIPAVNLGLWLAASFIVVYFQSSAHMEAAYGLAITVTMLMTTTLLTVYLSHYQKVKKVLVGLFFTVFIFIEGLFFAASAVKFMHGGYVVVIIAAMILFVMAIWHKSDQLFYKYLNSSNLNDYKEQMDKLRKDETYDLYHTNVVYLTAKMDKEWIDRSILYSILDKRPKKAKVYWFVKVNVTDEPYTSEYEVDMLGTDFIVCVNLYLGFHMRQEIPRYLRTIVTNLMESGRLPQQNQTYSITPGRKVGDFRFIILEEKLINARQMPGFERFVLQTKEQIKKITASPARWFGLHFSEVTVETVPLVLSDVKNLEIHERISEENQGES
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDK_ECOL6
Sequence: MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y809_STAAS
Sequence: MNPIVEFCLSNMAKGGDYVFNQLENDPDVDVLEYGCLTHCGICSAGLYALVNGDIVEGDSPEELLQNIYAHIKETWIF
What are the official names of this protein?
UPF0349 protein SAS0809.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.