PharMolix/UniProtQA huggingface dataset:
Protein: LSPA_WIGBR
Sequence: MKTKSNLIIISIFLIDFFTKKWILNNYEIFDSIKIFPMIKITYIRNYGIALGLFQSYSNLIRILIIVISIFILLFIFYMKNLCKDLLSNLGYSIIIGGSFGNIFDRIFYGSVIDFIDIYIYKWHFPVFNFADISIFIGFLILIYNKKIFIVNT
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFG_CLONN
Sequence: MARQYPLNKFRNIGIMAHIDAGKTTSTERILFYTGKTHKIGETHEGAATMDWMVQEQERGITITSAATTCFWKDHQINIIDTPGHVDFTVEVERSLRVLDSAITILDAKGGVEPQTETVWRQADKYQVPRMIFVNKMDILGADFYMSVQTVRDRLRANAVPIQIPIGKEDDYAGHVDLIKMKAVIFDKELGVNYDEVEIPEDLKDKAEEYRSAMIEAIVETDEELMMKYLEGEEISEEEIHTALRKATIANEIVPVLCGTAYKNKGIQHLLDAVLAYLPSPLDIPSIKGVDEDGNEVERHASDDEPLGALAFKIATDPFVGKLAFVRIYSGVMHSGSYVLNSNKNKKERIGRLVKMHANHREEVEELYAGELGAVIGLKNTTTGDTLCDENAPVILESMEFPEPVISVAIEPKTKAAQEKMGIALAKLAEEDPTFKTYTDQETGQVIIAGMGELHLEIIVDRLQREFKVECNVGAPQVAYKETIKNAVKAEGKFVRQSGGRGQYGHCWIELIPHEGEYEFENAIVGGAIPREYIPAVDNGIQEAAQSGILGGYPVINFKVKCYDGSYHDVDSSEMAFKVAGSMAFKNGMAKATPVLLEPVMKVEIVVPEEYMGDVMGDVNSRRGRIEGMNPRGGAQVIAAFVPLSEMFGYATVLRSRTQGRGTYSMEFANYEEVPKSIAEKVVGENK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y205_STAA3
Sequence: MKAHKIFWLNLAAIIIISIVVSGDMFLAMKWEQIHLKDGLKKVLSTYPIKNLETLYEIDGHDNPHYENNDQDTWYIESSYSVVGSDELLKEDRMLLKVDKNTHKITGEYDTTTNDKKNATDSTYKSYPVKVVNNKIVFTKDVKDPALKQKIENNQFLIQSGDLTSILNSNDLKVTHDPTTDYYNLSGKLSNDNPNVKQLKRRYNIPKNASTKVELKGMSDLKGNNHQDQKLYFYFSSPGKDQIIYKESLTYNKISEH
What are the official names of this protein?
Uncharacterized protein SAUSA300_0205.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: OL142_MOUSE
Sequence: MANKNNVTELIFTGLFQDPEVQKVCFVLFLPVYLATLLGNSLILVAVSISKTLHSPMYFFLSSLSLVEICYSSTIVPKFITDLLAKVKTISLKGCLTQIFFSHFFGVVEVILLVVMAYDRYVAICKPLHYMNIMSRQVCHMLVAGSWLGGFIHSIIQIIITIPLPFCGPNVIDHYFCDLQQLFKLACTDTFMEGFIVMANSGLISIVSLFILVSSYAVILISLRKRSAEGRRKALSTCASHITVVILFFVPGAFIYMRPSSTFTEDKLVSVFYTVITPMLNPIVYTLRNTEMKNAIRMSWKQKDS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 142, Olfactory receptor 227-2, Olfactory receptor 4C.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VPB37_MYCTO
Sequence: MRTTVTLDDDVEQLVRRRMAERQVSFKKALNDAIRDGASGRPAPSHFSTRTADLGVPAVNLDRALQLAADLEDEELVRRQRRGS
What is the function of this protein?
Probable antitoxin component of a type II toxin-antitoxin (TA) system.  Its putative cognate toxin is VapC37 (By similarity).
What are the official names of this protein?
Putative antitoxin VapB37.
Protein: RL27_ACIET
Sequence: MAQKKGGGSTRNGRDSKPKMLGVKAYGGELISAGSIIVRQRGTRIHPGVNVGVGKDHTLFALVDGHVSFGTKGALSKHTVSVTPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: AIM36_CANAL
Sequence: MFARLVPRLQPQLLSKRVLTARYPMLTTTPIYHQTPMQIIKRNYVIVHRERKKEPVIRYLFYMLVASWVAIYFVANRVDKKKPPQQSFTEREFQSYEEETGLKRRNKLISHTMNSKYKFYVIPYVHDEEELKKVANLLQHKDENATVKIIDPAQLIEEQKKDEGMKYHYLLEDLDEQGRPYPPGLITAVIKQEIYKILNTREGTFDTNFIIKNYPQTTNEAIKFENDISDIQKCLILHYDMLNELPKNKTDEEQRAIKNVDGYFDSVGKSKTLVEKFDPMDKEFEEIMLEDI
What are the official names of this protein?
Altered inheritance of mitochondria protein 36, mitochondrial, Found in mitochondria protein 39.
What is the protein family that this protein belongs to?
Belongs to the AIM36 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: LPXB_BURA4
Sequence: MSLPTNQLRLAMVAGEPSGDLLAASLLGGLQERLPASTRYYGIGGQRMLAHGFDSHWQMDKLTVRGYVEALGQIPEILRIRGELKRQLLAERPDAFIGVDAPDFNFSVEQAARDAGIPSIHFVCPSIWAWRGGRIKKIAKSVDHMLCLFPFEPAILDKAGVASTYVGHPLADEIPLEPDTHGARIALGLPADGPVIAVLPGSRRSEIGLIGPTFFAAMALMQQREPGVRFVMPAATPALRELLQPLVDAHPQLALTITDGRSQVAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILAGRFVVPELLQHFATPEALADATLTQLRDDANRRTLTEVFTEMHLSLRQNTAAKAAEAVVRVLDQRRGRA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: TRM1_METKA
Sequence: MELEIITEGRTPLKVPKTRGQPSARDPVFYNPAMQLSRDLTVSSLVQYGPKIVCDPLAGVGARGIRIAVELSPEVVVLNDLNPRAVELIEENVRLNDVEDVCRIENRDANALMHEDELAGRFDYVDIDPFGPPVPFLDAAVRTVRNRGVVGISATDVSALAGRYPRSARRKYWVEVERVEFYQEVAIRALISYIVRTCAKYDLAFEPHIAFFQRHHVRVIGEIRRGARRADRALKRLGYLLHCRECGYTSEREFDRECPRCGSGSVVRLGPLWLPDFADRERAERAASDARELGLEEAAELLETVAKETGTNPWAYDIHRWASRLGLSRVPSLTSVLEGLREEGFNAVRPHYSKRAVVKTDASPEEFEAVLTEVAGDSGCLHR
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: RL15_BORBU
Sequence: MFNLLKPKGASKRRKIVGRGPGSGLGKTSGRGQKGQKARNTSPRLGFEGGQTPLYRRLPRKGFSNSDYKLEYAIVNLGDIDKKFKDGQVVNYDTLLENKLIKKKNKKIKILSNGKLTKKVSFEVSKISKSAESLVIKIGCTIQLV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: Y144_CAMJR
Sequence: MGVKAYLDGILGEDKACKFLKKQGFEILKRNFHSKFGEIDIIAKKDEILHFIEVKFTQNDYEVSERLDRKKLEKILKTIEFYHLKNGISSDFQIDLICIKNDVIQFCENISF
What are the official names of this protein?
UPF0102 protein CJE0144.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: NLT21_PARJU
Sequence: MRTVSMAALVVIAAALAWTSSAEPAPAPAPGEEACGKVVQDIMPCLHFVKGEEKEPSKECCSGTKKLSEEVKTTEQKREACKCIVRATKGISGIKNELVAEVPKKCDIKTTLPPITADFDCSKIQSTIFRGYY
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Probable non-specific lipid-transfer protein 2, LTP 2, Allergen Par j II, Major pollen allergen Par j 2.0101, Protein P2.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: HTRAL_STAEQ
Sequence: MDNNKKQVIPRSQYRRKRREYFHNVEREERIRREKIEKENQAKREQHQTKVNEERVKDNLRKARIEKLTQEEIHQQRDDKSYKQKTLNQNNQMNKSKDDDNKIGEESLHDVRVSSDTSTLPHQNKSIKDYDDSGNESKQHTKLTSKESMLGVNSNHTEQDSRSTQPYSSKHSYSQPKDKDNDNTQQAQFLKKEDKQRNRAENIKKVNEFKQLVVAFFKEHWPKMLIIIGIIVLLLILNAIFTTVNKNDHTNDSAFNGTAKDETTAMKIAENSVKSVVTVENDLSNDTTVSDNKNESDNEIGSGVVYKKVGDSIYIFTNAHVVGDQEKQKVTYGNDKSVTGKVIGKDKWSDLAVVKAKVADENIKPMTMGDSNNIKLAEPILVIGNPLGTDFKGSVSQGIVSGLNRHVPVDIDKNDNYDALMKAFQIDAPVNPGNSGGAVVDRDGRLIGIVSLKIDMHNVEGMAFAIPINDVRKIAKELEHKGKVNYPNTEIKIKNVGDLDDSERNAINLPAKVNHGVLIGEVKENGLGDKAGLKKGDVIVELDGKKIEDNLRYRQVIYSHYDDQKTITAKIYRNGAEKNIKIKLK
What are the official names of this protein?
Serine protease HtrA-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: UT14A_MOUSE
Sequence: MNSIKATKGLLALSQQDDLMDLTSNYPLSASEDEGDSDGERKHQKLLEAIGSLSGKNRWKLPERSEAGLKVSEFNVSSEGSGEKLALSDLLGPLKPSSSLAAVKKQLSRVKSKKTLELPLHKREVEQIHREVAFSKTSQTLSKWDSVVQKNREAEQLVFPLEKEPSSFAPMEHVFREWKARTPLEQEVFNLLHKNKQPVTDPLLTPVEKASLKAMSLEEAKIRRAELQRARALQSYYEARARRMKKIKSKKYHKIVKKGKAKKALKDFEQLRKVDPDAALEELEKMEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLAKNKELTQKLQVVSESEEEGGADEEEALVPDIVNEVQKTADGPNPWMLRSCSRDAKENEIQADSEQLPESAAHEFPENEENDKPVAEEDELLKELEKRRSLRKRSELNQAAEPLGNQETKDSTSQEVLSELRALSKKLSKENHLSKKQKKSPAKAVDLVWEEEPAPEEDEPLLLQRPERMRTLEELEELGKEDSLPNKERPRPSVEGEQVRRNPQNHSKGKNKKEQMISLQNLLTTRTPSVTSLALPTTVEELEDEGARDQKQMIKEAFAGDDVIKEFLKEKREAIQANKPKAVDLTLPGWGEWGGMNLKPSARKRRRFLIKAPEGPPRKDKNLPNVIISEKRNIHAAAHQVRVLPYPFTHHQQFERTIQNPIGSTWNTQRAFQKLTAPKVVTKPGHIIKPITAEDVDCRSSPRSDVPVMQSNPKQHSKHQKQRKKSSIG
What is the function of this protein?
May be required for ribosome biogenesis.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 14 homolog A, Juvenile spermatogonial depletion-like X-linked protein, Jsd-like X-linked protein.
What is the protein family that this protein belongs to?
Belongs to the UTP14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL24_SALEP
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y5256_DICDI
Sequence: MSRAYLADNDKGWAKKKGADSHATPRPHKQTKMNKLKEIDTDQFLVPPVNAFKLDLDGDIRRGGNKKSERVSGFSGR
What are the official names of this protein?
Uncharacterized protein DDB_G0280919.
Protein: NDUS1_MACFA
Sequence: MLRIPVRKALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMIRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEVPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSALQRNDGAAILAAVSSIAQKIRMTSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDIEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAVEEPSIC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (By similarity).  Essential for catalysing the entry and efficient transfer of electrons within complex I (By similarity).  Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, Complex I-75kD, CI-75kD.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PPI1_STAAB
Sequence: MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Putative peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: MTNA_SCHPO
Sequence: MSLQAIIYNEDKLLVLDQLLLPYERKYISVSNVEDAFAVIKKMQVRGAPAIAIVAALSVAVGLKHLSEDADAKEYVINSFEHLKQSRPTAVNLFETAKFMQGIALQEGKNCRNKIIQEAERMLVKDLEDNHNIGTAGRKFLLQHYKDKDKLTVLTHCNTGSLATSGYGTALGIIRSLHESGNLEHAYCTETRPYNQGSRLTAFELVHDKIPATLVTDSTVASIMHKIDAIVVGADRVTRNGDTANKIGTYNLAILAKHFGKPFIVAAPFSSIDTSLASGSQITIEQRPPIEMTTITGPIITDSNSRNLEDPKRVRISIAAPGIDVYSPAFDVTPANLITAIATEKGFYTQQTNNKYDFS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL1_LACH4
Sequence: MPKHGKKYLDAAKKVDSNKLYSVAEAMKLVKETSYANFDATVDVAYNLSVDPKQADQQIRGSLVLPNGTGKTQTVVVFAEGPQADQAKAAGADFVGSDDLVQKIQDGWLDFDVVVATPMMMAKVGRLGRILGPKGLMPNPKTGTVTMDIEKAVKNVKAGQVEYRVDRQAAIHTPIGKVSFTEDQLVENFDALRDVILRARPASAKGQYIKSVAVSATFGPGIKLDPLNLD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NHAB_ECO81
Sequence: MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKVREVLQQFDDQSRLQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSLTGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLFYIFNGLLSSISDNVFVGTIYINEAKAAMKSGAITLKQYELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMGWIATL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS5_DESVH
Sequence: MLAILDYKAGNQTSVRRALDHLGIPCVITADPEVIQGAAGVIFPGVGAAGQAMNELVTTGLDEVLRRQVQAGRPLLGICVGCQIMLDYSQENDTKALGIIPGECRLFNPAWTDEDGAPIRVPHMGWNHIVQRRPCELLKGIEPEAEFYFVHSYYPAPPEEYVIATCTYGAEFCAIHGGPGLWAVQFHPEKSGRPGLRLLANFHRYCTEAADAQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_CLOB6
Sequence: MMPRLQEKYEKEVVSALMDKFGYKNIMEVPKLEKIVINMGVGEAKENQKSLEAAVEDLAKITGQKPILTKAKKSVANFKIREDMPLGCKVTLRKQNMYEFADKLINVALPRVRDFSGVSSKSFDGRGNYAIGIKEQLIFPEIEFDKIDKIRGMDIIFVTTAKTDEEARELLRFLGMPFAR
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TRM6_ASPOR
Sequence: MHSYVRPNQFVALRLPSEFTKIQKIEPDSTVFLGKFGSFPANQIIGRPFYLTFEILDDADEKDGSCLRIIPAAELHAETLIAEGEGDGEELDTNEDGTPMRTNREIVDDASTQKLTWEEIEALKKESGGAGREIISKLLESHQTLDQKTSFSLAKYMLRKRRKYMKRFTVLPLDVSILTNHMMEDQGAARIMELRDEMVGLLGCWGNVHHGGDASLDEAIAAKPNGRYLVVDDTGGLVVAAMAERMGILYPHDGDEYEEQGSSDEPKKNEAEQAHDDEQPPTESSTHRPARPAHMSASGNSITVLHPNKQPNLSLLKYFGYSQDNPDETHPLHKHLKTISWLQLLDPNADPIYSEEPEIIPESELYTMKSNKRGAYYRKRNRWTRVQSVVNEARAGEFDGLIVATVMDPSSVLKYAVPLLAGSAHVAVYSPSIEPLTELSDLYSTAKKTAFINRRQQLREQKLQQSSDQPDANETELQDSDLSELMAEFYLDPTLLLAPTLQNSRVRPWQVLPGRTHPLMSMRGGAEGYIFHAVRVIPTQQTIQAAGNLSRKKRKVVTQETPTTAVDSGSGVDVEMKS
What is the function of this protein?
Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6, tRNA(m1A58)-methyltransferase subunit trm6, tRNA(m1A58)MTase subunit trm6.
What is the protein family that this protein belongs to?
Belongs to the TRM6/GCD10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTAE_PESFW
Sequence: MFQSILFLAFYGRPVFGSAAARDYACVNTAESRDCWKDGFNIETDYYGKEEAPEGKLVEYELTLSQQIISPDGYEMLGMVVNGQYPGPTIEADWGDTLRITVKNNFTENYNGTAVHWHGIRQKETNWLDGVPGVTQCPITPGDSQVYEFRVTQYGTSWYHSHYSLQYSNGAYGPIVIHGPSSANWDVDLGPWLLSDWYHDDAFALDHVGITTNRAAIPKSSLINGKGYYECDPTNDAKCTGTRDYYEVVLKQGTKYKFGIINTSTILTYTFWIDGHNFTIIAIDFVPIEPLTVDTLNVGIGQRYEIIIETNPDFDDDSSFWMHAQYCFINQTDIVDDKVGIVRYESAGSSDPPYINKSDYHLNFGCADPKPESLVPILKQQVGAQANPLAAEDYFRVGLGNFTWPDATNSTGSVFLWFLQKLPLYVNWSEPSVKKLTIDETADFPPNSRPIELDYETGQWVYFVIESDWDPAGAVDQYGQEIRVEPSVHPFHLHGHDFLILAQGLGKFTSDIQPNLDNPPRRDTVDVEPLGYVWIAFQIDNPGAWLFHCHIAFHSSDGIAIQFLEQPSKLKPIMEEAGVLGDFADRCNKWDDWYQAVNIPHNATQADSGV
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes (PubMed:24302702).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA (PubMed:24302702).  As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain (PubMed:24302702).  The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrated to form endocrocin anthrone (PubMed:24302702).  Endocrocin anthrone is then converted to endocrocin, catalyzed by the anthrone oxygenase ptaC (PubMed:24302702).  Spontaneous decarboxylation of endocrocin occurs to generate emodin (PubMed:24302702).  An O-methyltransferase (ptaH or ptaI) could methylate emodin to form physcion (PubMed:24302702).  PtaJ could then catalyze the oxidative cleavage of physcion, and rotation of the intermediate could then afford desmethylisosulochrin (PubMed:24302702).  PtaF, a putative NADH-dependent oxidoreductase, might also participate in the oxidative cleavage step (PubMed:24302702).  Desmethylisosulochrin is then transformed by another O-methyltransferase (ptaH or ptaI) to form isosulochrin (PubMed:24302702).  Chlorination of isosulochrin by ptaM in the cyclohexadienone B ring then produces chloroisosulochrin (PubMed:24302702).  PtaE is responsible for the oxidative coupling reactions of both benzophenones isosulouchrin and chloroisosulochrin to RES-1214-1 and pestheic acid respectively, regardless of chlorination.
What are the official names of this protein?
Oxidoreductase ptaE, Dihydrogeodin oxidase, DHGO, Pestheic acid biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: EFG_STRPQ
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAVAETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIAYLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNAJ_LYCMC
Sequence: MNHLILIVAMCLMVIGVQCLKDGYLYDDVDCKFSCWDNEYCRKLCKSKKAVGGYCWRWRFSCYCTGLPDNEKTEGTYKCGQGRFLMGKDK
What is the function of this protein?
Binds voltage-independently at site-3 of voltage-gated sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin LmNaTx19.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIW_NATTJ
Sequence: MKITSPHFGEIEVNEDKIITFPTGLIGFSDCKRYLLLEGEQGTPFWYLQSVEQEDLFFVMIDPTNFFEDYQIEPSSQDLAAIDLKESENAVILTLVTVPEQDIKSATVNLKGPVIINPDRRLGKQIVLHPSDYTTKHPLFNDQGTKARGAV
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.