PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_RHILW
Sequence: MSVMDAIVVSKPPAHTSASLEKPSLIGLSREEMGAALRERGVAEKQIKMRVAQLWNWIYVRGVSDFDHMTNVAKDMREMLKQHFTIARPEIVEEQVSNDGTRKWLLRFPPRGAGRPVEIEAVYIPEEGRGTLCISSQVGCTLTCSFCHTGTQRLVRNLTAEEILSQLLLARDRLGDFPDREAPQGTIMPAEGRKVSNIVMMGMGEPLYNFDAVKQALLIATDGDGLSLSRRRVTLSTSGVVPEIFRTGEEIGVMLAISLHAVRDDLRDILVPINKKYPLKELIEACKAYPGLSNARRITFEYVMLKDVNDSLEDAKGLIKLLKGVPAKINLIPFNPWPGTNYQCSDWEQIEKFADFINSAGYASPIRTPRGRDILAACGQLKSESERMRKTERLAFEAMMIANHGADD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1053_HAEIN
Sequence: MFTDWKEHTSHVKKSFGELGKQYPKMLQAYQALGAAAAEGNVLDAKTRELIALAVAVTTRCESCISAHAEEAVKAGASEAEVAAALATAIALNAGAAYTYSLRALEAYSVQKA
What are the official names of this protein?
Uncharacterized protein HI_1053.
Protein: GCST_MOOTA
Sequence: MADLKKTPLYGEHVAAGAKMVEFGGWLMPVQYSSIIEEHQRVRNCAGLFDVSHMGEITIKGPDALALVQKLLTNDADRATGDRVIYSPMCYPDGGVVDDLLVYPRGEGEYLLVVNAGNIDKDFAWIQENASGFRVEVSNISAATAQLALQGPRALEILRPLTRVDLASLGYYRWTEGQVLGVHCLISRTGYTGEDGFELYFEAAAAPTMWRNILAAGREAGLVPAGLGARDTLRLEAALPLYGHELGPDISPLEAGLHRFVRLEKGEFNGREALAAQREAGVRRQLVGLTMIDRGIPRPEYPVLAAGKEIGYVTSGSLAPTLGQNIALALVAAGTVSTGGEVEVSIRGRVNRARVVKLPFYRRPKK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: CATV_NPVOP
Sequence: MNKIMLCLLVCGVVHAATYDLLKAPNYFEDFLHKFNKNYSSESEKLHRFKIFQHNLEEIINKNQNDSTAQYEINKFSDLSKEEAISKYTGLSLPHQTQNFCEVVILDRPPDRGPLEFDWRQFNKVTSVKNQGVCGACWAFATLGSLESQFAIKYNRLINLSEQQFIDCDRVNAGCDGGLLHTAFESAMEMGGVQMESDYPYETANGQCRINPNRFVVGVRSCRRYIVMFEEKLKDLLRAVGPIPVAIDASDIVNYRRGIMRQCANHGLNHAVLLVGYAVENNIPYWILKNTWGTDWGEDGYFRVQQNINACGIRNELVSSAEIY
What is the function of this protein?
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus.  May participate in the degradation of foreign protein expressed by the baculovirus system (By similarity).
What are the official names of this protein?
Viral cathepsin, V-cath, Cysteine proteinase, CP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: YAFQ_ECOLI
Sequence: MIQRDIEYSGQYSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLPAVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG
What is the function of this protein?
Cell death governed by the MazE-MazF and DinJ-YafQ TA systems seems to play a role in biofilm formation (PubMed:19707553).
What are the official names of this protein?
mRNA interferase toxin YafQ, Endoribonuclease YafQ, Toxin YafQ.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family. YafQ subfamily.
Protein: YCX4_TRICV
Sequence: MTKNKFVLLRYLCLFCTNIDQIDFNSVLK
What are the official names of this protein?
Uncharacterized 3.5 kDa protein in ycf33-trnY intergenic region, ORF29A.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1119_ARCFU
Sequence: MRLRWQTIVLLLLILGGASASAVYFSMKGNIDVIEDAISVSPASFSIDIAKGAHYVKEVKVKNSGGEAEIYFEDIVEGPDKSAIDVSFHTESGESISSSNKLRLPAGTADSPSETVIHVHIDVDDDAPTGSYAIYIHAKQ
What are the official names of this protein?
Uncharacterized protein AF_1119.
Protein: PGA42_CANAL
Sequence: MKFIILLFALIHITVAANRALIIDYSYYGCNLDCYIASNQENTCGAHDDDVSDQQYHACLCMNYDYFTNLMNCNCFDSNVYYVSSSICSMATASSEFETYDGAPSTMDVSTTDYSSSTEDISFTEDVSFTEDDSFTEYSSFTKYSSFTKYSSSVSSFTKVIWSTLETSSIKGIAATTSSYFTNAQTTSGTANDSSISKPSGSQIFVLCVISVVGFIFFFLFFLSLFV
What is the function of this protein?
Probable GPI-anchored cell wall protein that may be involved in cell wall organization, hyphal growth, as well as in virulence.
What are the official names of this protein?
Probable cell wall protein PGA42, Predicted GPI-anchored protein 42.
What is the protein family that this protein belongs to?
Belongs to the IHD1 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Protein: ERF1_OXYTR
Sequence: MVESIAAGQVSDNKHIEMWKVKKLISKLEHCKGNGTSMVSLIIPPKDDINKYGKLLTGEMSAAQNIKSRITKQSVVTAITSTKEKLKLYKQTPTNGLCLYCGVIYMEDGKTEKKINFDFEPFRPINQFLYFCGGKFQTEPLLSLLADDDKFGFIIVDGNGALYATLQGNSREILQKITVELPKKHRKGGQSSVRFARLREEKRHNYLRKVAELANQNFITNDRPNVTGIVLAGNAAFKNELAETDMLDKRLLPVICAVVDVSYGGENGLNEAITLAAEALTNVKFVAEKKLVSKFFEEIALDTGMIVFGVDDTMKALELGAVETVLLFEELDINRYVLKNPVKGDTKTIYLNSTQQKDSKYFKDRETGMDLDVVSEDSLAEWLCHNYQNYGAQVEFITDKSQEGFQFVKGFGGIGGFLRYKVDIEDHHGDLGAGGDDFDPDTDFI
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codon UGA.  In O. trifallax UAA and UAG codes for glutamine.
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, eRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_RHOCS
Sequence: MMVESKTPLLDTVNTPEDLRKLDPSQLRQFADELRTETINAVSVTGGHLGAGLGVVELTVALHYVFNTPADRLIWDVGHQCYPHKILTGRRDRIRTLRMGGGLSGFTKRAESEYDPFGAGHSSTSISAALGMAVGRDQLGHKNHVICVIGDGSISAGMAYEAMNNAGAMNSRMIVILNDNDMSIAPPVGAMSGYLSRLISSRQYRGLRELGKQVAERLPRPLQEAARRAEEYARGFVTGGTLFEEMGFYYVGPIDGHNLDHLLPVLENIRDDQGTGPVLIHAVTQKGRGYGPAERSADKLHAVSKFDVITGAQAKAKANAPSYTRVFADSLIQEAEADSRVVAITAAMPSGTGLDLFEKRFPDRTYDVGIAEQHAVTFAAGLAAEGLKPFCAIYSTFLQRAYDQVVHDVCIQNLPVRFAIDRAGLVGSDGCTHAGSFDVAYLGCVPNIVIMAAADEAELKHMVATAAAYDHGPIAVRYPRGEGVGLEMPERGQVLEIGKGRIVKEGTKVAILSLGTRLKEALLAAEDLNARGLSTTVADARFAKPIDEALIRRLAQDHEVLITVEEGSIGGFGSYVLHFLAQSGLLDQGLKVRPMVLPDIFQDQDAPAKQYDEAGLNARHIVETALKALGTGLAAETPAARA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PRUN2_XENTR
Sequence: MDIPLDAAEIRPEPPNSLDLNGSSTRKIKLTAPNINLSLDHSEGSILSDDNLDTPDELDINVDDLDTPDEADSFDYTGQDDQPALGEAVQEDFESIQEYTAEEERADNRLWRTVVIGEQEQRIDMKVIEPYKKVISHGGYYGEGVNAIIVFAACFLPDSSRPDYNYVMENLFLYVISTLELMVAEDYMVVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILALTRPFISSKFSSKIKYVSTLAELSELIPMEYVHIPETIVKLDEELRESESPKAGCLPNEPEMNTLEEEFENKMGDND
What are the official names of this protein?
Protein prune homolog 2, BNIP2 motif-containing molecule at the C-terminal region 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_SHEPC
Sequence: MAFKIASSPHVTRNLHTSTVMQRVILCLLPGLVVQCAFFGWGTLVQVLLAIIVALSAEAAVMKLRQRSIKASLSDNSAMLTAILIGVAIPPLAPWWMIVIGTAFAIIIVKHLYGGLGHNLFNPAMAAYVLLLISFPVQMTTWIAPSTVAMHSPSVLDSLQLIFNIGANVNMDQFRLGIDGVAMATPLDTLKTDLSMGLTRTESMTKAIFDGATGVGWFWVNLAYLAGGLVLLKLKAIRWHISTGVLAGLFIASSVGFLLSPDTQGSPLFHLFSGATMLAAFFIATDPVTAATSPRGRIIFGTLIGILVYIIRTQGGYPDAFAFAVLLANLCAPFIDYYVRPRSYGHSAG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBM48_BOVIN
Sequence: MASSGGQIGGVLDHHVQRAVCDSRAKYREGRRPRAVKVYTINLESWYLLIQGVPAVGAMKELVERFALYGTIEQYNALDEYPAEDFTEVYLIKFLNLQSARIAKRKMDEQSFFGGLLHVCYAPEFETVEETRKKLRERNAYVARMTKNKDHYMTKKHKDAKDFRGAFHSKTSGFPAASLNTSTGNSDLCLPYSSELPLCYFSPKCKCSSGERVDRPSNSSQDGRNFDETLGRCDHCDSLQKMQMKTLQNSLARPGTQKALTPSEAVDRFMPRTTQLQERKRRREDDCKRETLAEACTSSKEVMIGPQLPGIPKVDTHDGSWNTTASLIREKLKEVISSVPKPPEDKVEDVHRSRPLKQRRRI
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
RNA-binding protein 48.
What is the protein family that this protein belongs to?
Belongs to the RBM48 family.
Protein: HIS1_RHOPA
Sequence: MSAPFVLAVPSKGRLQENAEAFFARAGLTLSKPGGARDYRGTIAGLDNVEVAYLSASEIAANLARGSVHFGVTGEDLVRESITDADKRVLLIDGLGFGYANVVVAVPQAWIDVRTMADLDDVTTGFRAQHNRRMRVATKYINLTRGFFAQHSVVDYRIVESAGATEGAPAVGTAEMIVDITTTGATLAANGLKVLDDGVLLRSQANLVASREADWSDTARETARVILDHIASRARAGKYKEVRTRFKGCNDALLAEAHSRFGVVSPFGGPTSSGMLTLHCPPAQIYALGSFLRQHGADTVSVAALDYVFDKENPLFSKLAAFLPQ
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_BACTN
Sequence: MATKEFFPGIEKIKFEGKDSKNPMAFRYYDAEKVINGKKMKDWLRFAMAWWHTLCAEGGDQFGGGTKQFPWNGNADAIQAAKDKMDAGFEFMQKMGIEYYCFHDVDLVSEGASVEEYEANLKEIVAYAKQKQAETGIKLLWGTANVFGHARYMNGAATNPDFDVVARAAVQIKNAIDATIELGGENYVFWGGREGYMSLLNTDQKREKEHLAQMLTIARDYARARGFKGTFLIEPKPMEPTKHQYDVDTETVIGFLKAHGLDKDFKVNIEVNHATLAGHTFEHELAVAVDNGMLGSIDANRGDYQNGWDTDQFPIDNYELTQAMMQIIRNGGLGTGGTNFDAKTRRNSTDLEDIFIAHIAGMDAMARALESAAALLDESPYKKMLADRYASFDGGKGKEFEDGKLTLEDVVAYAKTKGEPKQTSGKQELYEAILNMYC
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPR1_ARATH
Sequence: MDTTIDGFADSYEISSTSFVATDNTDSSIVYLAAEQVLTGPDVSALQLLSNSFESVFDSPDDFYSDAKLVLSDGREVSFHRCVLSARSSFFKSALAAAKKEKDSNNTAAVKLELKEIAKDYEVGFDSVVTVLAYVYSSRVRPPPKGVSECADENCCHVACRPAVDFMLEVLYLAFIFKIPELITLYQRHLLDVVDKVVIEDTLVILKLANICGKACMKLLDRCKEIIVKSNVDMVSLEKSLPEELVKEIIDRRKELGLEVPKVKKHVSNVHKALDSDDIELVKLLLKEDHTNLDDACALHFAVAYCNVKTATDLLKLDLADVNHRNPRGYTVLHVAAMRKEPQLILSLLEKGASASEATLEGRTALMIAKQATMAVECNNIPEQCKHSLKGRLCVEILEQEDKREQIPRDVPPSFAVAADELKMTLLDLENRVALAQRLFPTEAQAAMEIAEMKGTCEFIVTSLEPDRLTGTKRTSPGVKIAPFRILEEHQSRLKALSKTVELGKRFFPRCSAVLDQIMNCEDLTQLACGEDDTAEKRLQKKQRYMEIQETLKKAFSEDNLELGNSSLTDSTSSTSKSTGGKRSNRKLSHRRR
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Key positive regulator of the SA-dependent signaling pathway that negatively regulates JA-dependent signaling pathway.  Mediates the binding of TGA factors to the as-1 motif found in the pathogenesis-related PR-1 gene, leading to the transcriptional regulation of the gene defense.  Controls the onset of systemic acquired resistance (SAR).  Upon SAR induction, a biphasic change in cellular reduction potential occurs, resulting in reduction of the cytoplasmic oligomeric form to a monomeric form that accumulates in the nucleus and activates gene expression.  Phosphorylated form is target of proteasome degradation.
What are the official names of this protein?
Regulatory protein NPR1, BTB/POZ domain-containing protein NPR1, Non-inducible immunity protein 1, Nim1, Nonexpresser of PR genes 1, Salicylic acid insensitive 1, Sai1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Accumulation in nucleus after induction by salicylic acid (SA) treatment or after pathogen infection.
Protein: UCRI_THEGE
Sequence: MLSVAARSGPFAPVLSATSRGVAGALRPLVQATVPATPKPPVLDLKRPFLSRESLSGQAVRRPLVASVGLNVPASVCYSHTDVKVPDFYDYRRLEVLDSTKSSRESSEARKGFSYLVTAVTTVGVAYAAKNAVTQFISSMSASADVLAMAKIEINLSDIPEGKNMAFKWRGKPLFVRHRTQKEIEQEAAVELSQLRDPQHDLDRVKKPEWVILIGICTHLGCVPIANAGDFGGYYCPCHGSHYDVSGRIRLGPAPLNLEVPPYEFTSDDMVVVG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).  UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer.  One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS) (By similarity).  The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function (By similarity).
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske, mitochondrial, Complex III subunit 5, Cytochrome b-c1 complex subunit 5, Rieske iron-sulfur protein, RISP, Rieske protein UQCRFS1, Ubiquinol-cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: FENR_CHLPD
Sequence: MTLNKVFFSGGEEIRDLCIVGGGPTGIFAAFQCGMNNISCRIIESMTQLGGQLAALYPEKHIYDVAGFPEVPAAGLVESLWKQAERYNPDVVLGEAVTRYSKLDDGSFEITTTSGSVYHSRAVLLAAGLGAFTPRKLPQLNAIDHLEGHSVFYAVKNMQDFAGKKVVIIGGGDSALDWAVGLLPVAERVTLVHRMHEFQGHGKTARDVEEAKERGAIDVYLNTEVTAIDTSGENLTKVHLCKKNGTGFQVEADRLLVLIGFKSNLGPLADWDLELVDNALVVDSHMKTSVDGLYAAGDIAFYPGKLKIIQTGLSDAAMAVRHSLTYIRPGEKVKHTFSSVKMAREKKNAK
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: HOA3_AZOSB
Sequence: MDLRGTRITVHDMTLRDGMHPKRHLMTLEQMKTIAQGLDQAGIPLIEVTHGDGLGGSSVNYGFPAHTDEEYLGAVIPLMKQAKVSALLLPGIGTVDHLKMAHELGVNTIRVATHCTEADVSEQHIRYARKLGMDTVGFLMMAHMNSPEGLVQQAKLMESYGANCIYVTDSAGHLLPDTVKARIGAVRAALKPETELGFHGHHNLAMGVANSIAAIEAGATRIDAAAAGLGAGAGNTPMEVLIAVCDLMGIETGVDVFKIQDVAEDLVVPIMDFPIRIDRDALTLGYAGVYGSFLLFAKRAEKKYGVPAREILVEMGRRGMVGGQEDMIEDTAITLAKAKQAQGVAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 3, HOA 3, 4-hydroxy-2-keto-pentanoic acid aldolase 3, 4-hydroxy-2-oxopentanoate aldolase 3.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: RS20_ECO24
Sequence: MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MEGL_PSEDM
Sequence: MNDKHKNFGFSTRAIHYGYNALENNGALIPPVYMTSTFAFPTVEYGAGCFAGEESGHFYTRISNPTLALLESRMAALENGEAGVAFSSGMGAIAATFWTLLRPGDEIIVNRTLYGCTFALLHHGIGEFGVVVKHVDMSNLAELEAAIGPATRMIYFETPANPNMQLVDIAAVSAIAHTHNDLIVVIDNTYCTPYLQRPLELGADVVVHSATKYLSGHSDITAGVVVTRQSLADRIRLQGLKDLTGAVLSPHDAHLLMRGIKTLALRMDRHCSSAQVIAQMLQDHPAVEWVAYPGLPSFPQYALASRQMKLPGGMIAFELKGGMAAGQRFMNALQLFSRAVSLGGAESLAQHPASMTHSTYTLEERAKHGISEGLVRLAVGLEDIADLLADIEQAMKAMA
What is the function of this protein?
Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia.
What are the official names of this protein?
L-methionine gamma-lyase, MGL.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.
Protein: RBMX_XENLA
Sequence: MVEADRPGKLFIGGLNTETNEKALEAVFCKYGRVVEVLLMKDRETNKSRGFAFVTFESPADAKDAARELNGKALDGKPIKVEQATKPSFSTPSRRGPPTSPRSRGPPRGLRGSRGGGSSRGQMPLKRGPPPRSGGPPPKRSAPSGPLRSSEMGGRAPLSRERDGYGAPPRRDPMPSRRDVYMSPRDDGYSGKDRYDGYSGRDYGSSRDSRDYGPPPRDYSYRDYGHSSSRDDYGSRGYSDRDGYGGRDSRDYSDHQSGGSYRDSYEGYGNSRSAPPARGPPPSYGGSSRYDDYSSTRDGYGGRDSYSSSRNDIYSSGRDRVGRQERGLPPSMDRGYPPPRDSYSSSSRGGPRGGGRGGSRSDRGGGRSRY
What is the function of this protein?
RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes.  Implicated in tissue-specific regulation of gene transcription and alternative splicing of pre-mRNAs.  Associates with chromatin.  Associates with nascent mRNAs transcribed by RNA polymerase II.  Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection.  Binds non-specifically to pre-mRNAs (By similarity).  Required for embryonic development, in particular of the brain.
What are the official names of this protein?
RNA-binding motif protein, X chromosome, Heterogeneous nuclear ribonucleoprotein G, hnRNP G.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1804_AERPE
Sequence: MSGTAGFITVSPGPPTEAPGGFPREPRGHRVRFISFKPYKFYWGFPNMSYITLTLPFNVGGGEAGDLFSTAWLFKTATHRMLSLAKQTPILPATDIGWKNTFRKAIYEVIPNRRYVDGVITLVRGIYESCRQLGVGFKEVELGDWLMFQQAEKEYPVRNITLKDDYSFYITTIGYNGEKDRIVVKPTIPKNYKVLLDKILEERQKHTARIVIKDYGVRKNRLWVHGEIQLTIPIDFYYKHMTRYRRNYGKLYGGVDVNVDRANLAVVDRYGRLRHVKTFWFEEASRKGCRSRRARSIIGMTVHDMLKYAYHHGVKTLFLENPDVLGKLKLLWIRNGKRLHRNYNWRVSVFRSRIIEMITMKTPLYAIRVEYVDPRRTTHSEEHDKIMKRYGLDRHSTSAYLIALRGIERYSPIQKVTA
What are the official names of this protein?
Uncharacterized protein APE_1804.
What is the protein family that this protein belongs to?
To A.pernix APE_1276 and S.solfataricus SSO2105.
Protein: ATPBM_SPIOL
Sequence: ASSAAAAXAPSTPLA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: NU3M_PANTR
Sequence: MNFVLILMTNTLLALLLMIITFWLPQLNSYMEKSTPYECGFDPMSPARVPFSMKFFLVAITFLLFDLEIALLLPLPWALQTANLPLMVTSSLLLITILALSLAYEWLQKGLDWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COX1_TRIRU
Sequence: MWKERWFLSTNAKDIGTLYLMFRYFSGLVGTAFSVLIRLELSAPGVQYIADNQLYNSIITAHAILMIFFMVMPALIGGFGNFLLPLLVGGPDMAFPRLNNISFWLLIPSLLLFVFASIIENGAGTGWTLYPPLASIQSHSGPSVDLAIFGLHLSGISSLLGAMNFITTIINMRSPGIRLHKLALFGWAVLITAVLLLLSLPVLAGAITMLLTDRNFNTSFFELAGGGDPIFIQHLFWFFGHPEVYILIVPGFGIISTVISANSSKNVFGYLGMVYAMMSIGILGFVFWSHHMYTVGLDVDTRAYFIAATLIIAVPTGIKIFSWLATCYGGSLNLTPAMLFALGFVVMFTIGGLSGVVLANASLDIAFHDTYYVVAHFHYVLSMGAVFALFSGWYFWIPKLLGLSYDLFAGKVHFWILFVGVNLTLFPQHFLGLQGMPRRIGDYPDAFAGWNLISSFGSIVSVVATWYFLNILYLQLTQGSPVSRYPWLTPQYFSDLFQHLFTRNNSSLEWCLNSPPKPHAFDCLPVQS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PAND_PYRIL
Sequence: MPVLLRAKAHGLVVTGKNLHYEGSLTLGRDIIEAAGFYPLEKVEVYNVTNGARFTTYVIPGRPGEVVLNGAAARLGEVGDVIIVAAYECVANPASHIATIAIFEGNKLKEVRKISLSDMY
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIGM2_REOVJ
Sequence: MARAAFLFKTVGFGGLQNVPINDELASHLLRAGNSPWQLTQFLDWISLGRGLATSALVPTAGSRYYQMSCLLSGTLQIPFRPNHRWGDVRFLRLVWSAPTLDGLVIAPPPILAQPAIQAQADRAYDCDDYPFLARDPRFKHRVYQQLSAITLLNLTGFGPISYVRVDEDMWSGDVSQLLMNYFGHTFAEIAYTLCQASANRPWEHDGTYARMTQIVLSLFWLSYVGVIHQHNTYRTFYFQCNRRGDAAEVWILSCSLTHSAQIRAGNRSLFVMPTSPDWNMDVNLILSSTLTGCLCSGSQLPLIDNNSVPNVSRNIHGWTGRGGNQLHGFQVRRMITEYCDRLRRDGVMTPAQQMQIEALGDQTQQFKRDKLEAWALEDDQYNRAHPNSTMFRTKPFTNAQWGRGNTAATSAAIAALI
What is the function of this protein?
Inner capsid (core) component.
What are the official names of this protein?
Inner capsid protein sigma-2, Sigma2.
What is the protein family that this protein belongs to?
Belongs to the orthoreovirus sigma-1 protein family.
What are the subcellular locations of this protein?
Virion. Note=Found in the inner capsid (150 copies).
Protein: ACP_CHLAD
Sequence: MASPEMEERLRKIIVDQLGVDEAQVVPSASFTKDLNADSLDLVELIMSIEEEFGVEIPDEDAEKIQTVADALQYLETHQSNE
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.