PharMolix/UniProtQA huggingface dataset:
Protein: BIOD_XANC8
Sequence: MQFPAFYVTGTDTGIGKTVASTALLHAVRARGHTAVGMKPVASGCVATPQGWHNEDALALQAASQPQPDYATLNPYALPAALAPELAAADVGVTLSLVPLQQALAQLRAQAEVVVVEGVGGWAAPLSAQLDQADLVRALQLPVVLVVGVRLGCINHARLTAAAIAADGLRCIGWIANEIDPQMERIEDNIRMLGQRLAMPCWGRIPWRPNAQAEGLAQHIRLPE
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_RICFE
Sequence: MADLAKIEEQLSSLTLMQAAELVKMLEEKWGVSAAAPVAVAAAGAAAPAAEAAAEKTEFEIVLMAAGDKKVEVIKVVKDITGLGLIEAKKLVDEAPKPMKSNVKKAEAEEIKGKLEAAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: LGT_HAEIN
Sequence: MNSNYLLLPHFDPSIFTLGDSNIGLRWYGLMYLLGFVFARWLAVRRANRPNSGWTVDQVDSLLFNGFMGVFIGGRVGDVFFYNLDHFLQEPLYLFRVWEGGMSFHGGLIGVIVAMIWTSYSQKRNFWQTADFVAPLIPFGLGLGRIGNFINLELWGRETNVPWAMIFPNDPLLLPRHPSQLYEAFLEGLVLFTILNIFIKKPRPMASVAGLFLIGYGVFRFIVEYVREPEVENFFGIITRGQALCLPMIIGGAFIMAWAYSRKSAVIK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSC_PYRAB
Sequence: MEGFTIWLTGPSGAGKTTLAVKLAKKLREMGYKVEILDGDTIRKTLYPNLGFSKEAREMHNRIVIYMAKLLTRNGVIAIVSLISPYKRIREYARKEIGRFMEVYVYAPLEVRIKRDPKGLYAKAIRGEIRGLTGYDGVYEEPENPEVKVDSSRMTPDEEAELVIRKAKELGYLP
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Probable adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: M1_I02A2
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYKKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMATITNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPNSSTGLRDNLLENLQAYQNRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: RL25_RHOPS
Sequence: MATVMELKATARPKSGKGAARAERRAGRVPGVIYGDNQPPLPISVEDKELRLRILAGRFLTTVFDVVLDGKKHRVIPRDYHLDPVKDFPIHVDFLRLGAGATIRVSVPLHLKGLESAPGVKRGGTFNIVTHTVDLEAPAESIPQFIEADVSTLDIGVSLHLSDIALPNGVKSVSREDVTLVTIVPPSGFNEEQKAAAAGAAAPAAAAAPAAKAGAAKAPAAAAKAPAAPAAKKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: VE1_HPV63
Sequence: MTDRGTNNDDWYIVDEAECRDDDESELEDLEDTYNSLFNRSESDISDLLDDTQQSQGNSLELFHLQEHLQNEQDLNTLKRKYLNSPPQASATETACNSLSPRLESITISQREKKARKQLFTQNDSGIELSLCQDEVDNINEALQEQVDIVQSLGGGVRDCIGVDILKCSNTRSALLAKFKDTVGVSFTDLTRAYKNNKTCCSYWVIAVWGVTSTSVDVVKTVFQVQCNYMHVEHCLTEKNKFLIVLAGFKAQKSRETVLNLVTSSLNVQSNYIMAEPPKNRSMAAALYWYRRSMSPAVYTWGEMPDWMAQQTLLNHQLASEKHFELSQMVQWAYDNGYTDESDIAYYYAILAEEDENAKAFLASNAQAKYVKDCARMVSHYKRAEMSSMSMSAWIYKRLEEVENGGDWKHIVKFLRFQEVEFISFMIAFKELLSGKPKKNCLVIYGPPNTGKSMFCMSLLRVLKGKVISYVNSKSQFWLQPLASTKIALLDDATKPAWDYIDLFLRNALDGNPICVDLKHKAPQQIKCPPLMITSNINVKADVCWMYLHSRITCFEFKQPFPFDENGQPAFSLTDINWKSFFERFWSQLDLSDQEDEESDGKPQQPLRLATRAASNSI
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RXLRP_PHYIT
Sequence: MKSLHAVNLVLLLLLACFAPAPATRELNLRAAASDSTRVVDNATTERLLRAHSSGKEEQKEEEERAISINFPSLEKILKNVTSGKSTELQGMLKADEALGSAFKTLKLSTMRIGKDDTKMVAKFLSSRNFKIWFQHAVKINKDDPYGEMLKALTNVFGEKNVAMMILVGNLSRNSRDVAKKLEKAQFYKWYFVDKYKTADEVFTNVLKADRNRIHGYGREKEIWGDYAKYVTTTVMKY
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves.
What are the official names of this protein?
RxLR effector protein PITG_14788.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm, host cytoskeleton. Host nucleus, host nucleolus. Host cytoplasm. Note=Associates with host microtubules.
Protein: Y1204_CLOBA
Sequence: MKKFNKDIGTYCENLACDYLIKNNFKILECNFKNRLGEIDIISIRNSILIIIEVKGRYNYEFGVPKESVSVSKQKNIIKVTKSYINYKKLYNFNVRFDVIEVYLNKIDSSYKINHIKDAFRT
What are the official names of this protein?
UPF0102 protein CLH_1204.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: MDTI_YERPN
Sequence: MQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGFGIAATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRG_DECAR
Sequence: MTKYVFVTGGVVSSLGKGIAAASLGAILESRGIKVTHLKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFTSAKMAKRNNFTTGQIYDSVLKKERRGEYLGKTVQVIPHITDEIKDRIKAGAEGADVAIVEVGGTVGDIESLPFLEAIRQMGIMEGRNNVCFMHLTLLPYIPTAGELKTKPTQHSVKELREIGIQPDILLCRADRSIPVEERRKIALFCNVMPEAVIECLDADSIYKIPGMLHEQMLDEIVCHKLNILAKAADLTVWENLIVALEHPLHQVKIAFVGKYVDLTESYKSLIEAIKHAGIHTRSQVNIIYLDSEDIEKNGTGVLEDLDAILVPGGFGRRGTEGKIAAIRYARENKVPYLGICLGMQLAVVEFARDVAGMPGAHSTEFVQDTPYPVIGLITEWLDASGKIEKRTEDSDIGGTMRLGAQVCKLGEGTLARSIYGAPEITERHRHRYEVNNTLLAKLEEKGLIVAGRAPGTDLCEMVELPADVHPWFVGCQFHPEFTSNPRQGHPLFSSYVKAALANQKAKGK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: GGR_ARCFU
Sequence: MYDVVVVGAGPAGSMAAKTAAEQGLKVLLVEKRQEIGTPVRCAEGISRESIEKFFEVDKKWIAAEVTGAKIYAPNKTEIVMSEEMAGNEVGYVLERKIFDRHVARLAAKAGAEVYVKTAMVDFERKDGKVKVKLRRLGEDWEVETKILIGADGVESKIGRKAGIIKTLKLNEVESCAQYLMTGLDIDESYTYFYLGRELAPGGYAWIFPKGNGSANVGIGVLPKMAERTAKEYLDAFIEKEGIEGKIVEFVAGAVPVYGEIETAVADNIMLAGDAAYHADPITGGGIANALSAGYYAGKVAAEAVQKNDFSADFLRRYDELWKNDFGKKLRRNKKLQLKFIDMDDALLNKLAGAIAGKNLREMSVAAIVKELLKAHPKLLWDLKDLF
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.  Is not active with NADPH as an electron donor.  Is not able to reduce the prenyl group of respiratory quinones.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUB_ARATH
Sequence: MSFTRWEVFFGLSVLALTMPFSAGVTNLRDVSAINNLYITLGAPSLHHWLAFGGDPCGEKWQGVVCDSSNITEIRIPGMKVGGGLSDTLADFSSIQVMDFSSNHISGTIPQALPSSIRNLSLSSNRFTGNIPFTLSFLSDLSELSLGSNLLSGEIPDYFQQLSKLTKLDLSSNILEGHLPSSMGDLASLKILYLQDNKLTGTLDVIEDLFLTDLNVENNLFSGPIPPNLLKIPNFKKDGTPFNTSIITPPPPPVVDPPPATHRAPPVPRIPPVSGVPPAPFAPFAPLQPQQHPPPSPPLVWSPPSSDNGGGDPWNSVSGQPTLQISPPSGSGSGKFWSTQRIILVVSSVAIIVLVSGLCVTLWRCCRSKIYNRYYSGARKDLQRPYFNKPPSQPTPTMGKVSREPMVKPFDGYGAGDRKYGYPMPQRAEESRRAMPPTSYYNKDVNTPQKPLQQPPRQFQSNDTASKRAAHFPPGLNSSSSATVFTIASLQQYTNNFSEENIIGEGSIGNVYRAELRHGKFLAVKKLSNTINRTQSDGEFLNLVSNVLKLKRGHILELLGYCNEFGQRLLVYEYCPNGSLQDALHLDRKLHKKLTWNVRINIALGASKALQFLHEVCQPPVVHQNFKSSKVLLDGKLSVRVADSGLAYMLPPRPTSQMAGYAAPEVEYGSYTCQSDVFSLGVVMLELLTGRRPFDRTRPRGHQTLAQWAIPRLHDIDALTRMVDPSLHGAYPMKSLSRFADIISRSLQMEPGFRPPISEIVQDLQHMI
What is the function of this protein?
Regulates the expression of transcription factors that define the cell fates.  Acts in a non-cell-autonomous fashion, functions in a radial inside-out signaling process, and mediates cell morphogenesis and cell fate across clonally distinct cell layers in floral primordia, developing ovules, and root meristems.  Seems to be required for the regulation of cell shape and the orientation of the mitotic division plane.  Involved in root hair specification, in the formation of the outer integument and the shape of organs such as carpels and petals and is necessary for the shape and height of the stem.  Non-functional SUB proteins are retained in the endoplasmic reticulum and degraded by endoplasmic reticulum-associated degradation (ERAD).  Collaboratively with QKY and POQ, regulates cell growth anisotropy during gynoecium development, thus linking together cell-cell communication and cellular growth (PubMed:24173806).  Together with QKY, links RLK-dependent signal transduction and intercellular communication mediated by plasmodesmata (PD) to regulate tissue morphogenesis (PubMed:25256344).
What are the official names of this protein?
Protein STRUBBELIG, Leucine-rich repeat receptor kinase-like protein SUB, Protein SCRAMBLED.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RNFG_VIBCM
Sequence: MLTAIRKNGLILAVFACVSTGLVALTYALTAEQIQQQEQKQLLQVLNQVIPHKYHDNPLAQACTLVNDDKLGTAKTMHAYLAQRDGQPTAIAIETIAPDGYNGEIKLIVGIANNGTVLGVRVLAHQETPGLGDKIDLRISNWVLGFNGQQVTADNQDDWKVRKDGGQFDQFTGATITPRAVVLAVKKAVEYVNQHQQQLHNQPNPCEGQ
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rnf electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GLI2_CHICK
Sequence: LMAGHPNYGDILMQSGGAAGTAHLHEYLSPVDVSRFSSPRVTPRLSRKRALSISPLSDASIDLQTMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGTISPAFSFPHPINPVTYQQILTQQRGLSSAFGHTPPLIQPSPTFPPRQHMAVISVNPPPAQISSNSNCISDSSQSKQSSESAVSSTVNPVINKRTKVKTEVEGLPQYPQPRQEHLTDLKEDLDKDECKQEPEVIYETNCHWEGCTKEYDTQEQLVHHINNDHIHGEKKEFVCRWQDCTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHPRPPPLKENGDNEASAKQSSKVSEESPEANSTTRSMEDCLQVKTIKTENSVMCQSSPGGQSSCSSEPSPLGSTNNNDSGVEMNMHGGGSLGDLTGWMTRLPVVDSTVSSGNLTVSLQLRKHMTTMQRLEQLKKEKLKTVKDSCSWVNPAPQGRNTKLPPISGNGSILENSGGSSRTLPNPRIMELSVNEVTMLNQINERRDSTTSTISSAYTVSRRSSGISPYFSSRRSSEASQLGHRPNNTSSADSYDPISTGGREFDIKL
What is the function of this protein?
Functions as transcription regulator in the hedgehog (Hh) pathway.  Functions as transcriptional activator.  May also function as transcriptional repressor.  Binds to the DNA sequence 5'-GAACCACCCA-3' (By similarity).  Is involved in the smoothened (SHH) signaling pathway.  Required for normal skeleton development (By similarity).
What are the official names of this protein?
Zinc finger protein GLI2.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium.
Protein: ASTD_BURMS
Sequence: MTELFIDGAWRDGAGPVFASRNPGTGEPVWEGAGASADDVERAVASARRAFAAWSALDLDARCAIVKRFAALLVERKEALATMIGRETGKPLWEARTEVASMAAKVDVSIAAYHERTGERRSPTADGVAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAPGVARATVEIWRDAGLPAGVLNLVQGEKDTGVALANHRQIDGLFFTGSSDTGTLLHRQFGGRPEIVLALEMGGNNPLVVADVEDIDAAVHHAIQSAFLSAGQRCTCARRILVPRGAFGDRFLERFADVASRITADVYDADPQPFMGAVISARAASRLVAAQAKLLELGAAPIIEMRQRDPALGFVNASILDVTPVRELPDEEHFGPLAQIVRYTDLDDAIARANDTAFGLSAGLLADDETVWNTFRRTIRAGIVNWNRPTNGASSAAPFGGAGRSGNHRPSAYYAADYCAYPMASVESAQLQMPANLSPGLHF
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: DER_AZOSB
Sequence: MKPTIVLVGRPNVGKSTLFNRLTKTRDALVADQPGLTRDRHYGVGRVGDRDYLVVDTAGFDPVAKDGIMHEMARQAEQAIAEADVLLFLVDGRAGRTPHDDQIAAHLRRAGRPVVVVVNKAEGLDRATVAADFHALGLGAPLAVSAAHGDGVKALVELVLAPFPADDEVEAAEDAGPRVAIVGRPNVGKSTLVNTLLGEERVIAFDMPGTTRDAIAIPFERGGKQYTLIDTAGLRRRGKVFEAVEKFSVIKTLQAIQEANVVVLVLDAAQDISDQDAHIAGFVLDTGRALVVAINKWDAVDDYRRARLKEDMARKLAFLSFARFHQISALRAEGIAALLKSVDGAYAAAMSNLSTPRLTRTMQAAVAKQAPPRHGSARPKLRYAHQGGMNPPVIVIHGNALDHIPNSYVRFLERTFMEAFKLQGTPLRIQFRTAHNPYATKA
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RHAR_ENT38
Sequence: MGVPLILRKTDFFANAGQAVAVADRYPQNVFAEHTHEFCELVLVWRGNGLHVLNDRPYRITRGDLFYIRAEDKHSYASVNDLVLQNVIYCPDRLKLNVDWASNIPGFNDARGAPHWRLSSNGMGQVRPVITQLEQESLKADQSANEMAELLFAQLVMTLKRFRYATDNPSANEQEALLDKLITALAGSLNRSFVLEKFCEQEQCSERALRQQFRTQTGMTVNHYLRQLRICHAQYLLQHTELMVSEVAMRCGFEDSNYFSVVFNREVGMTPVQWRHRSRKAA
What is the function of this protein?
Activates expression of the rhaSR operon in response to L-rhamnose.
What are the official names of this protein?
HTH-type transcriptional activator RhaR, L-rhamnose operon transcriptional activator RhaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WZC_SALTY
Sequence: MTEKAKQSAAVTGSDEIDIGRLVGTVIEARWWVLGTTAIFALCAVIYTFFATPIYSADALVQIEQNAGNSLVQDINSALANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVTKNTFPLFGAGWERLMGRHNEMVKVTTFTRPETMSGQIFTLKVLGDKRYQLVSDGGFSAQGVVGQPLNKDGVTMRVEAIDARPDTEFTVSKFSTLGMINNLQNNLTVTETGKDTGVLSLTFTGEDRDQIREILNSITRNYLQQDIARKSEEAGKSLAFLAKQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLFTKAHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITEASTVGDVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNRGIESPQALEEHGISVYASIPLSEWQKARDSVKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMLTGVSPSIGKTFVCANLAAVISQTHKRVLLIDCDMRKGYTHELLGTNNVDGLSDILAGKGEIASCAKPTAIANFDLIPRGQVPPNPSELLMSERFGELIAWASSRYDLVLIDTPPILAVTDAAIVGRHAGTTLMVARYAVNTLKEVETSLSRFDQNGIQVKGVILNSIFRRATGYQDYGYYEYEYQSDSK
What is the function of this protein?
Required for the extracellular polysaccharide colanic acid synthesis.  The autophosphorylated form is inactive.  Probably involved in the export of colanic acid from the cell to medium (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase wzc.
What is the protein family that this protein belongs to?
Belongs to the etk/wzc family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_CAUVC
Sequence: MRIAFLGTPDFAVTCLAELVASGHEIVCVYSQPPAPRGRGQDLKPSPVHAFAEGLGLPVRTPVSMKTPEEIAAFQALDLDAAVVVAFGQILVKDVLEAPKHGCFNLHASLLPRWRGAAPIQRAIMAGDAVTGVQVMRMSEGLDEGPILMSQQVAIADDDTAASLHDKLAAVGARLLPVALAAIEREVVQETPQAEDGVTYAKKIKSAEARIDWTRPAAEIDRHIRGLSPFPGAWFEAPSEKGPVRVKALLSRVEAASGVAGTTLDDALLIACGEGSIRLLKAQREGKGVQDAQTFTRGFPIATGTVLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RNH2_HAEIN
Sequence: MFEYPQGYKLIAGVDEVGRGPLVGAVVTAAVILDPHNPIEGLADSKKLSEKKRLALAEEIKEKARAWALGRAEADEIDEINILQASLLAMTRAVKSLKIQPHFVLIDGNKIPKDLAIPAQAVVKGDSLVAEISAASILAKVARDQEMEELDKQYPEYAFAQHKGYPTKLHLEKLAELGALPQHRRSFAPVKKALEQF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_MEGAT
Sequence: MAHPSQLGLQDAASPVMEELLHFHDHALMIVFLISTLVLYIIVAMVSTKLTDKYTIDSQEIEIVWTVLPAVILI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: K1PF_MYCPN
Sequence: MLNHNSKVWIVNYACAIDYYLDKHKQQRGVLTPGGKGINMAIVMALFGIKPTVLTFLGQPTKDLFLQLLKPYQLDLVSFPATTQTRINVKLLDGAQTTEINDVTPLIEEQAVHEMIAYLKANVKPNDLLVLNGRFLQRDLVKLLDVAFSLTKYVVLDVDEPQLLQLLNQRQPWLMKPNRDEFVAMVNANNSNVDQQELVQLIKQFQTTQNLLMSDGAQGAYFFDQQQLLFMEAIPPQQLVSTTGAGDTLLGVFLANLLLDKDPVGSLKVAVNYASATISKLAVVNSNDQIVLKATNYYYL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.
What are the official names of this protein?
Putative 1-phosphofructokinase, Fructose 1-phosphate kinase, Fru1PK.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: ATPG_FLAJ1
Sequence: MANLKEIRNRITSVSSTMQITSAMKMVSAAKLKKAQDAITAMRPYAEKLTELLQNLSATLEGEVGGAYTTQREVKKVLLVAITSNRGLCGAFNSNVIKEIKNRTDFYAGKQVDVFAIGKKGNDVLSKTHKVHGHHNAIFDHLTFENVAGIADNLTEKFLSGEYDKIELIYNQFKNAATQIVQTEQFLPLAPLKSEVSASAGDYIFEPSKEEIVLTLIPKSLKTQLYKGIRDSFASEHGARMTAMHKATDNATELRNQLKLTYNKARQAAITNEILEIVGGAEALNG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PA2GF_HUMAN
Sequence: MKKFFTVAILAGSVLSTAHGSLLNLKAMVEAVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTIENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGFLNVYCQGPTPNCSIYEPPPEEVTCSHQSPAPPAPP
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids.  Hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids (phospholipase A2 activity), the catalytic efficiency decreasing in the following order: phosphatidylglycerols > phosphatidylethanolamines > phosphatidylcholines > phosphatidylserines (PubMed:11112443).  May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases (By similarity).
What are the official names of this protein?
Group IIF secretory phospholipase A2, GIIF sPLA2, sPLA2-IIF, Phosphatidylcholine 2-acylhydrolase 2F.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted. Cell membrane; Peripheral membrane protein.