PharMolix/UniProtQA huggingface dataset:
Protein: ROK1_ASPFU
Sequence: MDAFKLLTRATKLKSGAAPSSTQSLTRLPSTGKAANPQLFRSSEADKVLEEASHGKKRKRVAGPEAAELDDDDDAELNFFGSSKARRSSASMAKEQAKEQQEQQEHRDDTSDADDVDEMDEVQCRTVLNAHKIKVTDMRDLEEIQPVRIESEEPKKKKKKTKQQEESTPALTKKEQKKARRVYPQPLVSFKELRTRYKISRRLAENIAEQGFTVPTEVQLGTLPLLLGGFKASGNSKSAESIEPDLLVVAPTGSGKTLSFLIPVINKIVRHHHEQEKERGIFSVIVAPTKELASQIVNEGRKLVHGTGVKITLMKKGMRVVDREDDDDENSHSEDSEEGSDSEQDEPSTTRKKKGKAPITKSDILVTTPLLLVNALSANRTKPMATLPLVRNIVLDEADVLLDELFREQTLDIWRACTHPELRASLWSATMGSNIEDLAKSTIKERKQAYDQTKSYPLLRLVVGLKDSAIPNIEHKLVYAATEQGKLLGLRQLLHPAAASVSDVRLRPPFLIFTQTIPRAIALHSELRYDIPAEAGGSSRIAVLHSDLSDGQRSEIMKNFRKGEIWILVTTDLLARGVDFRGINGVVNYDIPNSAAVYVHRVGRTGRAGREGGIAVTYYTKEDIPYVKSIANIIDVSEKLRGKDGEKSIQKWLLDALPDLSKKDKKELKKHGVKARQSTLKSVKDDKEHRRTRISTKSGYDRRMENKKKALIAASRNRKSKTQSTDPGSDDESWDGLDG
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase rok1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LCL2_ARTOC
Sequence: MLRTALLGLLFITTAKAQFQFFEQMFGGGQQHQESSSQGGNVPSDSAWYQNTYNGAQCSNYLCPGTLACVAVPHHCPCAHPQVEDKFEFGEGSAICASKGGFKAGETARKIELARKGLL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: OPGG_ECOSE
Sequence: MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DSBB_NEIG1
Sequence: MTPLFRKAVWLLFAVSVCAFAGSLAAQYVLGMEPCVLCISQRLCVLATALCAAVVLACKPKGRVGGLSGAVFISIPAVTGISVAAYQLWLQSLPPGAAPSCGAPWTFRLKGWPLFDWFEPVVRGFGNCAEPDYLLGVALPVWSAAYFLAVVLTVWWAWARAK
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXB_MANSM
Sequence: MRSIMENLIKNNPTIAIVAGEVSGDILGGGLIKALKVKYPQARFVGIAGKNMLAESCESLVDIEEIAVMGLVEILKHLPRLLKIRSDIVQKLSALKPDIFIGIDSPEFNLYVEDRLKAQGIKTIHYVSPSVWAWRQNRIYKIAKATNLVLAFLPFEKAFYDRFNVPCRFIGHTMADAIPLNPNRTEACKMLNIDENQRYVAILAGSRGSEVEFLAEPFLQTAQLLKRKYPDLKFLVPLVNEKRRRQFEQVKAKVAPELDLILLDGHGRQAMIAAQATLLASGTAALECMLCKSPMVVGYRMKAATYWLAKRLVKTAYISLPNLLADEMLVPEMIQDECTPEKLVEKLSVYLDETESAVQNRQVLIQRFTELHQLIQCDADSQAAQAVADLLEGKVNG
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: QOX4_STAES
Sequence: MNTIVKHTVGFIASIVLTLLAVFVTLYTNMTFHAKVTIIFGFAFIQAALQLLMFMHLTEGKDGRLQSFKVIFAIIITLVTVIGTYWVMQGGHSSHL
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
What are the official names of this protein?
Probable quinol oxidase subunit 4, Quinol oxidase polypeptide IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRDL2_MOUSE
Sequence: MVPGVRIIPSLLGLVMFWLPLDSQARSRSGKVCLFGEKIYTPGQSWHPYLEPQGTIYCVRCTCSENGHVNCYRLRCPPLHCSQPVMEPQQCCPRCVDPHVPSGLRVPLKSCQLNETTYQHGEIFSAQELFPARLSNQCVLCSCIEGHTYCGLMTCPEPSCPTTLPLPDSCCQTCKDRTTESSTEENLTQLQHGERHSQDPCSERRGPSTPAPTSLSSPLGFIPRHFQSVGMGSTTIKIILKEKHKKACTHNGKTYSHGEVWHPTVLSFGPMPCILCTCIDGYQDCHRVTCPTQYPCSQPKKVAGKCCKICPEDEAEDDHSEVISTRCPKVPGQFHVYTLASPSPDSLHRFVLEHEASDQVEMYIWKLVKGIYHLVQIKRVRKQDFQKEAQNFRLLTGTHEGYWTVFLAQTPELKVTASPDKVTKTL
What is the function of this protein?
Implicated in tumor angiogenesis (By similarity).  May inhibits BMPs activity by blocking their interaction with their receptors.  Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation.  May play a role during myoblast and osteoblast differentiation, and maturation.
What are the official names of this protein?
Chordin-like protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: RLPA_PSEAE
Sequence: MSKRVRSSLILPAVCGLGLAAVLLSSCSSKAPQQPARQAGISGPGDYSRPHRDGAPWWDVDVSRIPDAVPMPHNGSVKANPYTVLGKTYYPMNDARAYRMVGTASWYGTKFHGQATANGETYDLYGMTAAHKTLPLPSYVRVTNLDNGKSVIVRVNDRGPFYSDRVIDLSFAAAKKLGYAETGTARVKVEGIDPVQWWAQRGRPAPMVLAQPKQAVAQAAPAAAQTQAVAMAQPIETYTPPPAQHAAAVLPVQIDSKKNASLPADGLYLQVGAFANPDAAELLKAKLSGVTAAPVFISSVVRNQQILHRVRLGPIGSADEVSRTQDSIRVANLGQPTLVRPD
What is the function of this protein?
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
What are the official names of this protein?
Endolytic peptidoglycan transglycosylase RlpA, Rare lipoprotein A.
What is the protein family that this protein belongs to?
Belongs to the RlpA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: METN_BORA1
Sequence: MIHIKNLSKTYATPHGRFEALRGIDLLIEQGEVFGIIGPSGAGKSTLVQCINLLERPDQGSISIGGQELTGLSEAQLRGQRRRIGMVFQGFNLLSRRTVYGNVALPLEIAGVPRQEIPGKVERLLALVGLEHLRDRYPSQISGGQKQRVGIARALANDPDVLLSDEATSALDPETTHNILALLRDINRKTGVTVVMITHQMEVVREICDRVAVLSHGQVVEMARTQDVFATPQHDVTRAMVSAATSSALTESTLAAVQARIAARAAEQPGSAARLWRLSLTGKDAGGALISDLARQHALDISLVQARVDDIQGVAVGTLFVLAQGTPQAVNNALAALAAHQISVEEIAHEPANDRPALHVAA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AROK_FRATO
Sequence: MIRTKNIFLIGPVGAGKSTIGKQLAKQLKLEFIDSDDVIEKKCGVDINWIFDLEGEEGFRKREREVISEILAEKQNIVLATGGGAILDPETRSLLSSRGKVVYLEATIEQQLERTSKDTKRPLLRVDDKRPVLEQLMAEREPLYRSIADVVVETNGATVKNIVNKISTFLVEETIL
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSK23_HUMAN
Sequence: MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWRLGCMLASMIFRKEPFFHGRDNYDQLVRIAKFLGTEDLYGYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANVMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAATGAQQ
What is the function of this protein?
Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.  Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down-regulating expression of the tumor suppressor protein, PML.  May play a role in the pathogenesis of the lung cancer development and progression.
What are the official names of this protein?
Casein kinase II subunit alpha 3, CK II alpha 3, Casein kinase II alpha 1 polypeptide pseudogene.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
Protein: NADD_KLEP3
Sequence: MVDMTQLQAIYGGTFDPVHYGHLKPVEILANQIGLSKVIIMPNNVPPHRPQPEATSAQRVHMLKLAIADKPLFTLDERELQRDTPSWTADTLQAWRQEQGAEKPLAFIIGQDSLLTFPTWHRYETILDNVHLIVCRRPGYPLTMAHDADQQWLDRHLTHDVERLHNRPAGAIYLAETPWFDISATIIRQRLERGESCAEMLPATVLDYIREQGLYC
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RF1_BORPA
Sequence: MKPSMRSRLEQLAHRLIEVDALLAEPETAADMDRFRKLSRERAELEPVVEAFNAFLGVEADVATAQEMLSDPDMKAMAEDEIKTGRARIEEMEAALQLLLLPRDPDDGRSLFLEIRAGTGGDESALFSGDLLRMYTRYAETRGWRVEIMSESESELGGYKEVIVRIDGDGAYGRLKFESGAHRVQRVPATEAQGRIHTSACTVAVMPEADAMSDIVINPSDLRIDTFRASGAGGQHINKTDSAVRITHVPTGLVVECQDDRSQHRNKDKAMQVLAARLKDKEMRERQSKEAAERKSLIGSGDRSERIRTYNYPQGRVTDHRINLTLYKLQQIMEGDLDELTGALLAEHQAEQLAALGHDL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_YERE8
Sequence: MVNKRMQTLLMQLRQQGIQDERLLQALEAVPRERFVDEALSHKAYENTALPIGSGQTISQPYMVARMTELLQLTPTSRVLEIGTGSGYQTAILAHLVEHVCSVERIKGLQWQAKRRLKQLDLHNVSTRHGDGWLGWASRGPFDAIIVTAAPPEIPNALLEQLDEGGILVLPVGEQAQTLKCVQRRNNEFKVETVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_SHESA
Sequence: MKFFVIALIVLLGLLQYRLWSGDNSLPEYFVLQKQIAAQQEGNAKLNERNQVLKEEIIDLKSGTEAIEERARNELGMVKEGETFYRVVGGDRSVSSPSQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: I1B1_CONRA
Sequence: GHVPCGKDGRKCGYHADCCNCCLSGICKPSTSWTGCSTSTFD
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels.  Produces general excitatory symptoms (By similarity).
What are the official names of this protein?
Iota-conotoxin-like R11.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SKIP5_ARATH
Sequence: MELHEISKLDNKKHPERIVESKMKKRMKPYSLTSLNNLDDGCLMHILSFLSPIPDRYNTALVCHRWRYLACHPRLWLRVDRFVKDLSQPGVFLNIESAVSAARPGDTILIVAGGNYRVSNIQIKKPLCLVGGGEIPDETTLVCARGSDSALELLSTCKLANLTVKAELGCCLLHRSGRLTIDGCVLQCETNPLDHLSCPIVSTAGDEDIENILSHVEVKETVTGKIKANSVTVLQTRIEGGAKAVSTRGDLVLQRVRVMYSKAYLYFWFDVDYE
What are the official names of this protein?
F-box protein SKIP5, SKP1-interacting partner 5.
Protein: CKLF8_MOUSE
Sequence: MEEQQRARSHTVTTTTSSFAENFSTTSSSFAYDREFLRTPPGLLIVAEIVLGLLVWTLIAGTEYFRVPAFGWVMFVAVFYWVLTVFFLIVYITLTYTRIPQVPWTTVGLCFNGSAFVLYFSAAIVDASSVSPEKEGHNFNSWAASSFFAFLVTICYAGNTYFSFIAWRSRTAQ
What are the official names of this protein?
CKLF-like MARVEL transmembrane domain-containing protein 8, Chemokine-like factor superfamily member 8.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PAND_YERP3
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLEAAGILEYEAIDIYNVDNGQRFSTYAIAAERGSRIISVNGAAARCACVGDKLIICSYVQMSDAAARLHHPKVAYFEGENQLQRKAKAVPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB2_PYRCJ
Sequence: MGEEVSIGATAVGIKTKEGVVLAAEKRVSYGFYTLSTAGKKVFIVNDRLAIASAGIIADMQTLAKILKLNAKAYELEMKRKPSVHAMAKLLSVVMFSRRFMPFFAEVLVGGIDDEGPHLIVMDPLGSLIEDNYAALGTGAKLAIAIIDASYKPDMSLQDAKKLAVQALKAALERDPVSGGGIDLVVIDKNGAREEEVKLQVLI
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_SHEB8
Sequence: MSITKDQILEAFAAMSVMEVVELIEAMEEKFGVSAAAAVVSGGAEAAVVEEQTEFNVVLTAHGDNKVAVIKAIRGATGLGLKEAKAMSEAAPVAVKEGVSKEEAEALKKELTEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RL20_CAMC1
Sequence: MARVKTGVVRRRRHKKVLKLARGFFSARHKHFRKAKEQLERSLVYAYRDRRQKKRDFRRLWIVRINAACRLNDISYSRFINGLNKANIELDRKILADLAMNDAKAFAALAKQAKDALK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NPT2A_MOUSE
Sequence: MMSYSERLGGPAVSPLPVRGRHMVHGATFAYVPSPQVLHRIPGTSTYAISSLSPVTLTEHSCPCGEVLECHDPLPTKLAQEEEQKPEPRLSQKLAQVGTKLLKVPLMLAFLYLFVCSLDVLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHVTGLVVASFNIRGGRDAPDLLKVITEPFTRLIIQLDKSVITSIAVGDESLRNHSLIRIWCHPDTTEASTSMSRVEAIGSLANTTMEKCNHIFVDTGLPDLAVGLILLAGSLVVLCTCLILLVKMLNSLLKGQVMSSRRSSTQTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSSFQIALCHFFFNISGILLWYPLPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQAMVGVGTPFGALLAFVVLVNVLQSRSPGHLPKWLQTWDFLPRWMHSLQPLDGLITRATLCYARPEPRSPQLPPRVFLEELPPATPSPRLALPAHHNATRL
What is the function of this protein?
Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (PubMed:8070635, PubMed:7478940).  The cotransport has a Na(+):Pi stoichiometry of 3:1 and is electrogenic (By similarity).
What are the official names of this protein?
Sodium-dependent phosphate transport protein 2A, Sodium-phosphate transport protein 2A, Na(+)-dependent phosphate cotransporter 2A, NaPi-7, Sodium/phosphate cotransporter 2A, Na(+)/Pi cotransporter 2A, NaPi-2a, Solute carrier family 34 member 1.
What is the protein family that this protein belongs to?
Belongs to the SLC34A transporter family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of the proximal tubules.
Protein: AP1M1_YEAST
Sequence: MASAVYFCDHNGKPLLSRRYRDDIPLSAIDKFPILLSDLEEQSNLIPPCLNHNGLEYLFIQHNDLYVVAIVTSLSANAAAIFTFLHKLVEVLSDYLKTVEEESIRDNFVIIYELLDEVMDYGIPQITETKMLKQYITQKSFKLVKSAKKKRNATRPPVALTNSVSWRPEGITHKKNEAFLDIVESINMLMTQKGQVLRSEIIGDVKVNSKLSGMPDLKLGINDKGIFSKYLDDDTNIPSASATTSDNNTETDKKPSITSSSATNKKKVNIELEDLKFHQCVRLSKFENEKIITFIPPDGKFDLMNYRLSTTIKPLIWCDVNVQVHSNSRIEIHCKAKAQIKRKSTATNVEILIPVPDDADTPTFKYSHGSLKYVPEKSAILWKIRSFPGGKEYSMSAELGLPSISNNEDGNRTMPKSNAEILKGPVQIKFQIPYFTTSGIQVRYLKINEPKLQYKSYPWVRYITQSGDDYTIRLT
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  The AP-1 complex interacts directly with clathrin.  AP57 is probably a subunit of the Golgi membrane adaptor.
What are the official names of this protein?
AP-1 complex subunit mu-1-I, Clathrin assembly protein complex 1 mu-1-I medium chain, Clathrin coat assembly protein AP54, Clathrin coat-associated protein AP54, Golgi adaptor AP-1 54 kDa protein, HA1 54 kDa subunit, Mu(1)-adaptin, Mu1-I-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side.
Protein: PSBM_DIOEL
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COX2_OENBE
Sequence: MIVNECLFFTIALCDAAEPWQLGFQDAATPMMQGIIDLHHDILFFLILILVFVLWILVRALWHFYYKKNPIPQRIVHGTTIEILWTIFPSIILMFIAIPSFALLYSMDEVVVDPAMTLKAIGHQWYWTYEYSDYNSSDEQSLTFDSYMIPEDDLELGQLRLLEVDNRVVVPVKTNLRLIVTSADVLHSWAVPSLGVKCDAVPGRLNQISMLVQREGVYYGQCSEICGTNHAFMPIVIEAVSATDYTNWVSNLFIPPTS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MUTS_BURP6
Sequence: MATQIDASSEAAAATAAAQHTPMMQQYLRIKSEHPDTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGTPIKMAGVPHHAVEQYLAKLVKFGESAAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKSDVFLLALCVGHNKRGVASNIGLAWLNLASGALRLAELAPDQLGAALERIRPAEILAADGTIESVPAGMGAITRVPAWHFDIASGTQRLCDQLEVASLDGFGAQALTSANGAAGALLIYAAATQGQQLRHVRSLKVENESEYIGLDPSTRRNLELTETLRGTESPTLYSLLDTCCTAMGSRLLRHWLHHPPRASVAAQARHQAIGALLDAPPNAGLDSLRSALRQIADVERITGRLALLSARPRDLSSLRDTFAALPALRERVAEIASNAAALGRLGAALEPPPGCLDLLTRAIAAEPAAMVRDGGVIARGYDAELDELRDISENCGQFLIDLETRERARTGISNLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERALYDGVLQALLPHIEGCQRVASGLAELDLLAAFAERARTLDWVAPEFTDEIGIEIDQGRHPVVEAQVEQFIANDCALNPERKLLLITGPNMGGKSTFMRQTALIALMAYVGSYVPAKAARFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPHSLVLMDEIGRGTSTFDGLALAWAIARHLLSHNRCYTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVEEGPANQSYGLQVAQLAGVPAPVIRAARKHLAHLEQQSAAQATPQLDLFAAPTVVDEPECNEPPAAATPHPALERLLELDPDDLKPRDALDLLYELHTLARSGPADAQR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DADA_SALEP
Sequence: MRVVILGSGVVGVTSAWYLSQAGHDVTVIDRESGPAQETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTPFQLKWMWQMLRNCDTRHYMENKGRMVRLAEYSRDCLKTLRAATGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLARMAEQAGVTFRFNTPVEKLLYENDQIYGVKCADEIIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIVEPDGAPVSTILDETYKIAITRFDKRIRVGGMAEIVGFNTDLLQPRRETLEMVVRDLFPRGGHIEQATFWTGLRPMTPDGTPVVGRTRYKNLWLNTGHGTLGWTMACGSGQLLSDILSGRTPAIPYDDLSVARYRSDFTPTPPQRLHSAHN
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.