PharMolix/UniProtQA huggingface dataset:
Protein: Y1986_ARCFU
Sequence: MLSVLLIAEDGEWHRYKELEECLINDYHVDYSGQISTDIAELSRIEFSYEIIFFLKPVEFSEIPAISRLAKSKILVFHVLNNNVPIRLSENLLPVADCLELNASAMRGKLEYFRGVDVIKLLHPYHMEVDEECEVILNGNRNTKVLLGDITFRTGKNVVFGVRKGNMAFFSADIFSNDALKESDNCRFIKNLIKELVGKAEVY
What are the official names of this protein?
Uncharacterized protein AF_1986.
Protein: AGRP_HUMAN
Sequence: MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQALLPELPGLGLRAPLKKTTAEQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT
What is the function of this protein?
Plays a role in weight homeostasis.  Involved in the control of feeding behavior through the central melanocortin system.  Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland.  Has very low activity with MC5R (By similarity).  Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity.  It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
What are the official names of this protein?
Agouti-related protein.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus lumen.
Protein: NLP6_PLAVT
Sequence: MRTTSPYSHCSHVEMNAGAFVTMLLVALSVCVAAAVDPDVIQPFPQPKPTTIAQKAAVKYKPLLYTSMVVCVPYAAVDAAGRVTDGLKGRHGNDGCTYARHGSQVYGRVEPYGNLSAIMYAWYFPKRFWLGFPIQRHDWKSVVVWIDNLESKVSAIVAVSMAKSDTKYNTETELDANDFARLQVDNQIVISNTSLRFEFFEFGLRSSYLRLTGYNGQYQNLIMWDQLTDAAREALNDDNNFGSAVVPLSDKQFKAHVKEAYPSKSVR
What is the function of this protein?
Probable secreted effector that may act as a pathogen-associated molecular pattern (PAMP) recognized by the plant immune system.
What are the official names of this protein?
NLP effector protein 6, Nep1-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the Necrosis inducing protein (NPP1) family.
Protein: PSAL_PROM0
Sequence: MSDFQKSFSESTSSIKFDEKYIDTSVQPNDIGVAEQWAVKTVADPCVGNLATPVNSGYFTKAFINNLPFYREGISPNFRGLETGAAFGYLLYGPFTMTGPLRNSEFALTAGLLATIGAVHILTALFVLYNAPGKAPNVQPPDATVNNPPKDLFTRAGWADFTSGFWLGGCGGAVFAWLLVGTLHLDSIMPIIKNIWTAG
What are the official names of this protein?
Photosystem I reaction center subunit XI, PSI subunit V, PSI-L.
What is the protein family that this protein belongs to?
Belongs to the PsaL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: APNO_AGRRK
Sequence: MTVIALFGAGGKMGYRLAKNLKGSRFDVRHVEVSDAGKARLKNDLDLSCVPVDEALNGAEVVILAVPDTAIGKVAAGIVDKLKPGTMVVALDAAAPFAGHLPKRDELTYFVTHPCHPPIFNDETDMQAKKDHFGGLFAKQHIVSALMQGPESAYALGEEIAKVIWAPVMRSHRVTVEQMAMLEPGLSETVCASLLVVMRQAMDECVARGVPEDAARDFLLGHMNVLGAVIFKEVDGVFSDACNKAIEFGIPALMRDDWKNVFEPKEIAASIQRIT
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes the conversion of D-apionate to 3-oxo-isoapionate.
What are the official names of this protein?
D-apionate oxidoisomerase.
What is the protein family that this protein belongs to?
Belongs to the ApnO family.
Protein: MSCL_BARQU
Sequence: MLKEFKEFALKGNMIDLAIGVIIGGAFGGLVNSIVNDILMPIIGFITGGIDFSNMFIQLAGEKQATLSAAKTAGATISYGNFITLLINFLIIAWVLFLFVKGMNKIRRKQEKEESSKKMSLEEQLLSEIRDLLAKKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DDIAS_MOUSE
Sequence: MNKRRKFLFASVLAVQNSNFIYPSCQRCFSKIILESKRFTCPKCGSSGDTGSTNYRYKLSLKVAESSKLFFITVFGSCLDTFFGLTATGLHRYLGDSIKNLETLDSGRTQSLLTTAVEKCFVGQSFVFGVTNFGDVCGHDSDSSNFQQPCCKHRGEVRTLVASQIILPSPHVKGFTVIAYLHPLLHKKPHCGSQEHSSQSLTSDDSDSDLNNIQGSGNTSWFSESSVGEDFFRYWEPSLELTSSDSQVTSSDDFPASKQIMASGTPNQNRHCISVSEVTSSKNCHDSLQSLWSLHSCMDKNNTTGKLGEELGLPSPVCNSCHESRLSDSHFFPSQMQEPFEEHNLECYSKAEKNDYSQYDIACYQHHEVNTTPILQQRSSAFSLSSLKPEETANPSQNSDSLIWDDLPLSESLNKFLAVVESEVAVTEIDAKNRKQGMDKSIDKCHKNYSRLSLTPWRNTRALNTSCFSLRSSQAMMKDSGKEALFSNCKSNSSPHIQKESKADKTEAAVSIAGSRSDISEDFLPDTCSSALFTSSKDREAFITQKRTSGVLQQRNEISCRPSTSISDCSDLRSRYFTGCGQKLHSGTKGKLAIQNCSKKYSDASDLHKLENKHRWPKKEDDNFTICRKLTYPLETLCSSPESINTSKEMPYRPSNNNLTPSSSGDHEGSYNASADLFDYIAKDKDIGTEITKIPQDNLLPLEVPCTENYPINENRGQPSQKPSLQSISPSRYSRPRSQSDSECDFEESQDFVPCSQSTPVAGFHQRIHGLNGASKILPSIYSNPNANYKNRKNSPLTGQYQATSACSKNVKAFRQKPESPFVSSLTQANVFNHCPAAESLGNDVDEWVPPTTKKVFISDILGFRVMGLRKCLDLHYSPDPKELPRKKLIKVTHKTNI
What is the function of this protein?
May be an anti-apoptotic protein involved in DNA repair or cell survival.
What are the official names of this protein?
DNA damage-induced apoptosis suppressor protein, Nitric oxide-inducible gene protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Accumulates in the nucleus in response to stress.
Protein: DPEP1_MOUSE
Sequence: MVIIWWFWSLLAICASDSFRDQAVAIMRTTPVIDGHNDLPWQLLNLFNNQLLRPDADLNKLAQTHTNIPKLKAGFVGGQFWSAYMPCDTQNKDAVKRILEQMDVIHRMCQLYPETFMCVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDRGDDEAESHGLSPFGKRLLNEMNRLGVMIDLSHVSVATMKDALQISRAPVIFSHSSAYSLCPHRRNVPDDVLQLVKNTSSLVMVNFFSNFVSCSDSATLPQVADHLDHIKKVAGAGAVGLGGDYDGVTMLPVGLEDVSKYPDLIAELLRRNWTETEVRGLLADNLIRVFSEVELVSNNMQSPEEVPITLKELDGSCRTYYGYSQAHSIHLQTGALVASLASLLFRLHLL
What is the function of this protein?
Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
What are the official names of this protein?
Dipeptidase 1, DPEP-1, Beta-lactamase, Membrane-bound dipeptidase 1, MBD-1, Microsomal dipeptidase, Renal dipeptidase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor, GPI-anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI-anchor. Note=Brush border membrane.
Protein: KAD_CUPNH
Sequence: MRLILLGAPGAGKGTQAKFICEKFGIPQISTGDMLRAAVKAGTPLGVEAKKVMDAGGLVSDDIIIGLVKDRLKEDDCKNGYLFDGFPRTIPQAEAMKEAGVAIDYVLEIDVPFDAIIERMSGRRVHVASGRTYHVKYNPPKTEGVDDETGEALIQRDDDKEETVKKRLDVYSQQTRPLVDYYSEWAAKGDASAKVAPPQYRKILGVGNVDEITARVFEALK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2464_BURA4
Sequence: MDARLLEILVCPICKGPLHYDRAAQELICNADKLAYPIRDGIPVMLVDEARQTVEGTPVDPAGPAGS
What are the official names of this protein?
UPF0434 protein BamMC406_2464.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: TYSY_ECOBW
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_DEIGD
Sequence: MKRSVPDLMNASEPLVMVTAYDYPGARHAEAAGVDLILVGDSLGNVVLGYDSTAPVTLDDMIHHARAVRRGAPNTFLVVDLPFGTYHTGVTDAMRNAVRVIQQTGADAVKLEGATPEVLDVVGVLARNGIPVMGHVGLMPQTATAQGGLKVQGRDEASARRTLEGALALEAAGAFSVVLEAIPARLARLITERLHVPTIGIGAGVHCRGQVLVYHDLLGLYEGDEKKLAKRYAELGKEAREAIAAYAREVRAREFPTKDQSFVMKDDVLGKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_AJECG
Sequence: MAPSNLPPVFNATSQDIEMLLAAQCHLGSKNLQVHMEPYLWKTRPDGINVINIGKTWEKIVLAARIIAAVDNPADICVISARPYGQRAVLKFAAHTGAVAIAGRFTPGNFTNYITRSFKEPRLIIVTDPRTDHQAIKEASYVNIPVIALCDTDSPTEFVDVAIPTNNKGRHAIGLIWWMLAREVLRLRGTLASRETEWDVVVDLYFYRDPEAEENKEIEEAKVPGAEEVGAAAIESGLVGDSWEAQAAPAFAGAGVPAGAAPGWEAEGGVDWAASSAAPADTWAGESGNPDAGVKW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALL3_OLEEU
Sequence: MADDPQEVAEHERIFKRFDANGDGKISSSELGETLKTLGSVTPEEIQRMMAEIDTDGDGFISFEEFTVFARANRGLVKDVAKIF
What are the official names of this protein?
Polcalcin Ole e 3, Calcium-binding pollen allergen Ole e 3.
What are the subcellular locations of this protein?
Endomembrane system.
Protein: CD59_SHEEP
Sequence: LQCYSCINQVDCTSVINCTXNQDACLY
What is the function of this protein?
Potent inhibitor of the complement membrane attack complex (MAC) action.  Acts by binding, in a species specific manner, to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore.
What are the official names of this protein?
CD59 glycoprotein, Complement inhibitory protein, CIP, MAC-inhibitory protein, MAC-IP, Membrane attack complex inhibition factor, MACIF, Protectin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: ARR24_ARATH
Sequence: MTRDQVAEELPNLAESKLTALVVDDSFVNQTIHQKLLNRLGIKNDVVTNGKEAVDVYCSGGNYDLILMDMDMPIMNGIQATKRLREMGIESKIAGVTTRANEGEKKEFMEAGLNDFQEKPLTISKLLSILHKLNFYVQT
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator 24, Arabidopsis response regulator 24.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUCC_TOLAT
Sequence: MNLHEYQAKQLFADYGLPVPSGIPCSSADEAVAATKKLGGDKWVVKCQVHAGGRGKAGGVKVAGSEQEVRAFADQWLGKRLVTYQTDANGQPVNTILVETCGNIAKELYLGAVIDRSSRRVVFMASTEGGMDIETVAHNTPELIHKAALDPLTGPQPYQARELGFKLGLNAEQLKQFTKIFLGLGKMFVACDLSLLEINPLVITGEGNLLCLDGKINIDSNALYRQPKLKAWNDETQEDPREVEAARWDLNYVALDGNIGCMVNGAGLAMGTMDIIKHHGGFPANFLDVGGGATKERVTEAFKLILSDSKVKAVLVNIFGGIVRCDLIADGVIGAVAEVGVKVPVVVRLEGNNADLGSKKLAESGLNIIAATSLTDAAEQVVKAAEAVA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: NADA_MYCPA
Sequence: MTVLNRMDTLAEDMVADITDSPTGYTGVDGDAQWAAEVRRLAKLRGATILAHNYQLPEIQDVADHVGDSLALSRIAAEAPEDTIVFCGVHFMAETAKILSPDKTVLIPDQRAGCSLADSITPEDLRAWKDEHPGAVVVSYFNTTAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQFLGAHVRRMTGRENLHVWAGECHVHAGINGDELGERARANPDAELFVHPECGCATSALYLAGEGAFPAERVKILSTGGMLDAANTTSARKVLVATEVGMLYQLRRAAPQVDFQAVNDRASCRYMKMITPAALLRCLVEGADEVHVDPGIAAAGRRSVQRMIEIGQPGGGE
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_CALS8
Sequence: MLDVDTILAIIISFLIVLIVMPVAIPFLRYLKCGQVVRDDGPQTHHKKSGTPTMGGLVIYLSILITSLLFYKKYPQIGAPLVCASAFGLIGFIDDFVKVVLKRSLGLRAREKLVLQFLISITFLYIVKKYLGTDVYIPILNRYVDLSWAYIPIMSVLMVFTVNAVNLTDGLDGLASGVTLIVGLFLAIVSIFSKKSDMAIFSGAIVGSCMGFLRYNAYPAMVFMGDTGSLMLGGAIFSIAVMLKQPVLVMIIGGLYIIEAISVMLQVMYYKLTKKRIFKMAPLHHHFELLGWDEAKVVVVFWIFTIIFCLVALAIIQI
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BMP2B_XENLA
Sequence: MVAGIHSLLLLQFYQILLSGCTGLVPEEGKRKYSESTRSSPQQSQQVLDQFELRLLNMFGLKRRPTPGKNVVIPPYMLDLYHLHSAQLADDQGSSEVDYHMERAASRANTVRSFHHEESMEEIPESGEKTIQRFFFNLSSIPDEELVTSSELRIFREQVQEPFKTDGSKLHRINIYDIVKPAAAASRGPVVRLLDTRLIHHNESKWESFDVTPAITRWIAHKQPNHGFVVEVTHLDNDTNVPKRHVRISRSLTLDKGHWPRIRPLLVTFSHDGKGHALHKRQKRQARHKQRKRLKSSCRRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNTNIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
What is the function of this protein?
Induces cartilage and bone formation.
What are the official names of this protein?
Bone morphogenetic protein 2-B, BMP-2-II.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZSCA2_HUMAN
Sequence: MMAADIPRVTTPLSSLVQVPQEEDRQEEEVTTMILEDDSWVQEAVLQEDGPESEPFPQSAGKGGPQEEVTRGPQGALGRLRELCRRWLRPEVHTKEQMLTMLPKEIQAWLQEHRPESSEEAAALVEDLTQTLQDSDFEIQSENGENCNQDMFENESRKIFSEMPEGESAQHSDGESDFERDAGIQRLQGHSPGEDHGEVVSQDREVGQLIGLQGTYLGEKPYECPQCGKTFSRKSHLITHERTHTGEKYYKCDECGKSFSDGSNFSRHQTTHTGEKPYKCRDCGKSFSRSANLITHQRIHTGEKPFQCAECGKSFSRSPNLIAHQRTHTGEKPYSCPECGKSFGNRSSLNTHQGIHTGEKPYECKECGESFSYNSNLIRHQRIHTGEKPYKCTDCGQRFSQSSALITHRRTHTGEKPYQCSECGKSFSRSSNLATHRRTHMVEKPYKCGVCGKSFSQSSSLIAHQGMHTGEKPYECLTCGESFSWSSNLLKHQRIHTGEKPYKCSECGKCFSQRSQLVVHQRTHTGEKPYKCLMCGKSFSRGSILVMHQRAHLGDKPYRCPECGKGFSWNSVLIIHQRIHTGEKPYKCPECGKGFSNSSNFITHQRTHMKEKLY
What is the function of this protein?
May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 2, Zinc finger protein 29 homolog, Zfp-29, Zinc finger protein 854.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: GREA_FLAPJ
Sequence: MSTVSYYTAEGLKKLKDELEQLKAIERPKASADIAEARDKGDLSENAEYDAAKEAQGLLELKIKKMEEVYSNARLIDESQLDVSKALVLSHVKIKNQSNGMEMSYHLVAESEADLKTGKISVTSPIGKGLLGKSVGEIAEITVPNGILKFEVLEITRD
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: POMP_MOUSE
Sequence: MNARGLGSELKDSIPVAELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVHRLPFLPSSNLSLDILRGNDETIGFEDILNDPSQSELMGEPHVMVEHKLGLL
What is the function of this protein?
Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes.  Degraded after completion of proteasome maturation (By similarity).  Mediates the association of 20S preproteasome with the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Proteasome maturation protein, Proteassemblin, Protein UMP1 homolog, mUMP1.
What is the protein family that this protein belongs to?
Belongs to the POMP/UMP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Microsome membrane.
Protein: SYC_XYLFT
Sequence: MSLHLYNTLHRRVEPFEPLDPACPTMYVCGPTVYNYVHIGNARGPVVFGVLAALLRRRYGALRYARNITDVDDKINTAAQEQGVPISAITERFCAAYREDMKKLGVEPPDIEPEATAHMPQIIAMIEQLIERQHAYVAMEHVLFAVNSFADYGQLSRRDTEEMLAGARVEIAPYKRDPSDFVLWKPSSDQLPGWDSPWGRGRPGWHIECSAMAAAHLGETIDIHAGGIDLQFPHHENEIAQSRCAHGSSTFARVWMHNGMLNFEGAKMSKSLGNIETVHELVAKHPPEALRYALLSAHYRKPLDWSEALIAQSVRTLNRLYGTLRDLAAYPARAIIPGNIEAALDDDLNTPQALAELATLANEARIQLADTTHHAAAEVTTALTRLKAKLLGAGLALGLLQQTPEAWFSQGTNESDETHIQALIDARGAAKQARDFVRADAIRAQLAAEGIVLEDTPQGVRWMKQHT
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET4_YEAST
Sequence: MVPAESNAVQAKLAKTLQRFENKIKAGDYYEAHQTLRTIANRYVRSKSYEHAIELISQGALSFLKAKQGGSGTDLIFYLLEVYDLAEVKVDDISVARLVRLIAELDPSEPNLKDVITGMNNWSIKFSEYKFGDPYLHNTIGSKLLEGDFVYEAERYFMLGTHDSMIKYVDLLWDWLCQVDDIEDSTVAEFFSRLVFNYLFISNISFAHESKDIFLERFIEKFHPKYEKIDKNGYEIVFFEDYSDLNFLQLLLITCQTKDKSYFLNLKNHYLDFSQAYKSELEFLGQEYFNIVAPKQTNFLQDMMSGFLGGSK
What is the function of this protein?
May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane.
What are the official names of this protein?
Golgi to ER traffic protein 4, Guided entry of tail-anchored proteins 4.
What is the protein family that this protein belongs to?
Belongs to the GET4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_PARL1
Sequence: MSDDRRRGDEDGGAGTGVITKTKPKTKKPSLYKVLLLNDDYTPMEFVVHVLERFFNKGRDEATVIMLHVHQHGVGICGLYTYEVAETKVTQVMDFAQQHQHPLQCTMERE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RS17_SYNY3
Sequence: MAIKERVGIVVSNKMDKTVVVAVESRSPHPKYGKIVVKTKKFKAHDEENQCQEGDKVRIQETRPLSKTKRWQVINIMSHSS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SAR1A_DICDI
Sequence: MFLFDWFWNVLSFLGLYNKNAKILFLGLDNAGKTTLLGVLKDGRLSSYLPTFHPTSEELAMGNIRFKAFDLGGHESARRLWKDYYPSVDAIVYLIDSSAQDRFVESKKELDSLLSSDELANVPFLILGNKVDIGNTSEEKFRASLGLTQTTGKGKTTLNGVRPIEVFMCSVVKRYGYAEGFRWLANYL
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
GTP-binding protein Sar1A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: APBB2_HUMAN
Sequence: MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKNSTPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNKNLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRGNHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTGAKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETDIWSDHSFQTDPDLPPGWKRVSDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNGGKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCFAVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDMLSLVDPMDRSVLHSQPIVSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGMLPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
What is the function of this protein?
Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength (By similarity).  Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning (By similarity).  Activates transcription of APP (PubMed:14527950).
What are the official names of this protein?
Amyloid beta precursor protein binding family B member 2, Amyloid-beta (A4) precursor protein-binding family B member 2, Protein Fe65-like 1.
Protein: CLPP_STAAE
Sequence: MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDD_BURP2
Sequence: MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFARSDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGTQFLYASSAAIYGGSSRFVEAREFEAPLNVYGYSKFLFDQVIRRVMPSAKSQIAGFRYFNVYGPRESHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYGPGEQTRDFVSVEDVAKVNLHFFDHPQKSGIFNLGAGRAQPFNDIATTVVNTLRALEGQPALTLAEQVEQGLVEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVDRYVRWLFGQL
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.