PharMolix/UniProtQA huggingface dataset:
Protein: LIMK1_DROME
Sequence: MHHQQRLRANGGRGGTGLGAGSGPVSGGHSPLCAHCRGQLLPHPEEPIVMALGQQWHCDCFRCSVCEGHLHNWYFEREGLLYCREDYYGRFGDACQQCMAVITGPVMVAGEHKFHPECFCCTACGSFIGEGESYALVERSKLYCGQCYGKRSCQPADAKARITTAGKPMHSIRLVEIPKDATPGLRVDGVALDDGCPTVRITDLFCNFFLWLTSMAEQCCGAPYRIDVNLTNLHIGDRILEVNGTPVSDSSVEQIDKLIRSNEKMLQLTVEHDPVQVCRSCSQADIQRAMSASTLILPLSTSASSVEVGRERLYKTPGEQGTKARKLRQATNASTTIPPAAGATAMTQLKEKERCSSLSKLLDEQHQAQQHSAHPQLYDLSRTQSCRVVQKPQRIFRATDLVIGEKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRVPPERLLHEIETFQEWYASSEDALSPTSQRSLNNLDELVKSAVDSEISPVEKEKENMVIKPQDIPKSPHLGKDFSPSGERLRDSMRARRRQRFLGAQEERRNLTPDTESKERALKKALKKCRPFGERGYLVDLRAGAELQLEDVRDLNTYSDVDSSCDTSLNYHDVNNLPAAQEDENTVKPGKEELLEESTNKPSNQESQHHRLAIDDMRTRLNQCRSKFEHLEEASRRNFNQSQHSMKNFFKTPPVALKMFQRLEHEAAALNGGNNCPPPPPRTQRINQTPIFGRKNPPVAIVGQKLQHAESLEDLASSGVAKQLATPAPKRSKATATTKGGQSSNPPLFLPPSLNISVALNSNGNVTTTTNTNSSCPPSASDWLPKKHKLTLPLPSAQQQRTSSNHRLPMCNNKGKTLKPLPSRTGSQGIPASNCVSPTRSSRPGSPTKHLAQRHTAATAQRLTNAAATHQQQHQQQSSKTTRLNILSPEKVHRLGARLTDQKQKMREEAAATASSVGGAGCAAGTAAGSLNGHRTIGSSGTPNSAVGERRRRAAPSPPVRTHFNTRC
What is the function of this protein?
Protein kinase which regulates actin filament dynamics.  Phosphorylates and inactivates the actin binding/depolymerizing factor tsr/cofilin, thereby stabilizing the actin cytoskeleton.  Modulation of actin cytoskeleton dynamics may be essential for imaginal disk morphogenesis and axon guidance.
What are the official names of this protein?
LIM domain kinase 1, LIMK-1, dLIMK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cleavage furrow. Midbody. Note=Localizes to the cleavage furrow and the midbody at cytokinesis.
Protein: SUN3_BOVIN
Sequence: MSGRPNSRGSSRLFRAPSEDASSGSSGSAVLPQEENPNASGLTRSWKAVMGMVFILTLLLLGFINHMKLKEKAFPQKSRQIYAVIAEYGSRLYNYQARLRMPKEQLELLKKESQTLENNFREILFLIEQIDVLKALLRDMQDGLHNYSWNADIDPAEGWNHTEVIDEEMSNLVNYILKKLREDQVQMADYALKSAGASVVEAGTSESYKNNKAKLYWHGIGFLNYEMPPDIILQPDVHPGKCWAFPGSQGHALIKLARKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGVLKQCEGEEIFLGQFVYNKTGTTVQTFALQHEVPEFLLCVKLKILSNWGHPNYTCLYRFRVHGTPKDDS
What is the function of this protein?
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton.  The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning.  May be involved in nuclear remodeling during sperm head formation in spermatogenesis.  A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
What are the official names of this protein?
SUN domain-containing protein 3, Sad1/unc-84 domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus envelope. Nucleus inner membrane.
Protein: PYRC_BACC1
Sequence: MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRAADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: YNXB_BACSU
Sequence: MKKLTIFSGGLGAVFSVLAQLFAVIDDSYTLGNLWFLGALAGIITMLASIQTNNKPVFSILLIASSVIGLLGTGLVYIIPTLFNIIIIYKFSKVSQ
What are the official names of this protein?
Uncharacterized membrane protein YnxB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2113_ACTSZ
Sequence: MPSFDIVSEITMHEVNNAVENANRALSSRYDFRGVEAVIELNEKNETVKVTTESDFQLEQLIEILIGACVKRGIDSTSLDIPAESEHHGKLYSKEIKLKQGIETEIAKKITKLIKDSKLKVQTQIQGEQVRVTGKSRDDLQSVIQLVKGADLGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein Asuc_2113.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: MNMA_ACIBT
Sequence: MQQRVIVGMSGGVDSSVSAALLLQQGYQVEGLFMKNWEEDDGTEYCTAMEDLADAQAVADKIGIKLHTANFAMEYWDRVFEHFLAEYAAGRTPNPDILCNKEIKFRAFLDHAMTLGADFIATGHYARRAETAYNSKGEAYAPLLRGLDNNKDQTYFLHAVHGREINKTLFPVGEIEKPEVRRIAEELDLATAKKKDSTGICFIGERRFNDFLKQYLPAQPGKIVLDNGKEVGEHHGLMYYTLGQRGGIGLGGMKGASEGAWFVLHKDVANNRLVVGQGHDHPLMQSTQLWSEAIDWVAGEQNIPAEGLRCTAKTRYRQPDQACTVFIDENSEHGVRVEFDEPQRAVTPGQSVVFYSDEVCLGGGVIHHTNAPTPNFI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3H_SCLS1
Sequence: MADTTSKEVPLHSVQVEALVVMKIVKACAATYPTTATGSIVGMDSNGTLQITNSFPFPTADVAASDSHPNDHMAASNIAAAAPRSKANIVYQSEMIKMLKEVNVDANNVGWYTSANMGNFINTSLIENQFFYQKEPNERTVALVHDVSRSAQGALSLRAFRLSPNFMTAYKEGKFTTENMQKSKLTYKDILVELPIIVHNSHLLTSFLHQMPVELPKKELDFPASLADLTRNTPPTPLYPNLESLDLSIDPYLERTCDMLLDSIETHYTELNNFQYFQRQLTREQAKVTAWKTKRAAENASRATQKLAPLPEDEWERLFKLPTEPSRLEGMLNARQVDQYSRQVDGFTASITGKMFAVKSNLLPEQS
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNG2_YEAST
Sequence: MDPSLVLEQTIQDVSNLPSEFRYLLEEIGSNDLKLIEEKKKYEQKESQIHKFIRQQGSIPKHPQEDGLDKEIKESLLKCQSLQREKCVLANTALFLIARHLNKLEKNIALLEEDGVLAPVEEDGDMDSAAEASRESSVVSNSSVKKRRAASSSGSVPPTLKKKKTSRTSKLQNEIDVSSREKSVTPVSPSIEKKIARTKEFKNSRNGKGQNGSPENEEEDKTLYCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIEMEKNKLKRKRN
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Involved in cell cycle progression and meiosis.
What are the official names of this protein?
Chromatin modification-related protein YNG2, ESA1-associated factor 4, ING1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the ING family.
Protein: G3P_AQUAE
Sequence: MAIKVGINGFGRIGRSFFRASWGREEIEIVAINDLTDAKHLAHLLKYDSVHGIFKGSVEAKDDSIVVDGKEIKVFAQKDPSQIPWGDLGVDVVIEATGVFRDRENASKHLQGGAKKVIITAPAKNPDITVVLGVNEEKYNPKEHNIISNASCTTNCLAPCVKVLNEAFGVEKGYMVTVHAYTNDQRLLDLPHKDFRRARAAAINIVPTTTGAAKAIGEVIPELKGKLDGTARRVPVPDGSLIDLTVVVNKAPSSVEEVNEKFREAAQKYRESGKVYLKEILQYCEDPIVSTDIVGNPHSAIFDAPLTQVIDNLVHIAAWYDNEWGYSCRLRDLVIYLAERGL
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDKA_XANC5
Sequence: MVSFDATEALAPYREGRGYGAILFDRERLRQADASLFSPQSWGDRARPVDAGGRGGAWFVDAPFGHSVLRQYLRGGMAARVSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAACYLREGVGYRAALLMERLENVRSLADHAQVAGRGAPWEATGQLIARFHRAGLDHADLNAHNILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSREDVDKDYARLHRAYELAWGRGY
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL1_GRABC
Sequence: MAHNKRLKAARASVDSTKFYPLTEAVALAKTNARAKFDETIEISLNLGIDPRHADQMVRGLVSLPNGTGKTLRVGVFARGPKAEEAKAAGADVVGAEDLAELVQNGTIEFDRCIATPDMMALVGRLGKILGPRGLMPNPKLGTVTMDVKGAVTAAKSGQIEFRAEKAGIIHAGIGKASFDADKLVENIRALVDAIQKAKPTGAKGTYLQKAALSSSMGPGMRLDVSSLTV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: EX7S_ECO45
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAGL3_PONAB
Sequence: MANRGPSYGSSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM
What are the official names of this protein?
Transgelin-3.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
Protein: ENDD1_HUMAN
Sequence: MGTARWLALGSLFALAGLLEGRLVGEEEAGFGECDKFFYAGTPPAGLAADSHVKICQRAEGAERFATLYSTRDRIPVYSAFRAPRPAPGGAEQRWLVEPQIDDPNSNLEEAINEAEAITSVNSLGSKQALNTDYLDSDYQRGQLYPFSLSSDVQVATFTLTNSAPMTQSFQERWYVNLHSLMDRALTPQCGSGEDLYILTGTVPSDYRVKDKVAVPEFVWLAACCAVPGGGWAMGFVKHTRDSDIIEDVMVKDLQKLLPFNPQLFQNNCGETEQDTEKMKKILEVVNQIQDEERMVQSQKSSSPLSSTRSKRSTLLPPEASEGSSSFLGKLMGFIATPFIKLFQLIYYLVVAILKNIVYFLWCVTKQVINGIESCLYRLGSATISYFMAIGEELVSIPWKVLKVVAKVIRALLRILCCLLKAICRVLSIPVRVLVDVATFPVYTMGAIPIVCKDIALGLGGTVSLLFDTAFGTLGGLFQVVFSVCKRIGYKVTFDNSGEL
What is the function of this protein?
May act as a DNase and a RNase.  Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.
What are the official names of this protein?
Endonuclease domain-containing 1 protein.
What is the protein family that this protein belongs to?
Belongs to the DNA/RNA non-specific endonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: GMHBB_PSEPK
Sequence: MKLLILDRDGVINYDSDAYIKTLEEWVPIPGSVDAIAQLSKAGWTVAVATNQSGIARGYYPLATLEAMHARLRALVAEQGGEVGHIVYCPHGPDEGCDCRKPKPGMLRAIAEHYQIGLEGVWFVGDSKGDLEAALAVGAQPVLVKTGKGERTLEKGVPETTLIFDDLAAIARELI
What is the function of this protein?
Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate (beta-HBP) intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the gmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_HALMA
Sequence: MSQGTLYDKVWDQHKVTTLPNGQDQLFVGLHLIHEVTSPQAFGMIKERGLEVARPDLTHATVDHIVPTANQDRPYSDDAAETMMAELEENVRDAGIQFSDPTTGDQGIVHVIGPEQGITQPGKTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATQTIAMEKQKVRKIEVTGELDEGVEAKDIILEIIRRLGTEGGVGYVYEYAGETIENLDMEGRMSICNMSIEGGARAGYVNPDETTYEWLEETDYFQEHPEKFEELKPYWESIRSDEDAEYDDVVEIDAGELDPVVTWGTTPGQGIGIDDPIPEPEDLADDKVDTARRAQKHMRVEPGETMEGYDIDVAFLGSCTNARLPDLRRAARIVKGREVADDVRAFVVPGSQRVQRAAEEEGLKDIFEEAGFEWRNAGCSMCLGMNEDQLEGDEACASSSNRNFVGRQGSKDGRTVLMNPRMVAAAAITGEVSDVRDLKEVTLA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: STON2_MOUSE
Sequence: MTTLDHVIATHQSEWVSFSEEPLFPTPLEGGTEEHFPGLSSSSERSESSSGENHVVDEGSQDLSHSEQDDSSEKMGLISEAASPPGSPVQPTPDLASAISNWVQFEDDTPWSSTSPPHKETALTLTMPCWTCPSFDSLRRCPLTSESSWTTHSEDTSSPSVAPSYTDLQLINTEEQASGRASGTDSTDNSSSLQEDEEVEMEAISWWAGSPAMNGHPAAPPVTTARFPSWVTFEDNEVGCPSPPVPSPKKPNTPSAATAAPDVPFNSTGSFKRDRPKSTLMNLPKVQKLDISSLNRPPSVIEAPPWRATNPFLNETLQDVQPSPINPFSAFFEEQERRSQNSSVSSTTGKSQRDSLIVVYQDAISFDDSGKSQPHPDAIEKLKQLQIDDPDPVGNTALPDDDPTASVELDAPSPASALSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTASGYLQLYYEQGLEKPFREFKLEICHEVSEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHAAEREQVIKLGTTNYDDFRSFIHAVQDRLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGTVGKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILIKGNEIVSRQDIMPTTTTKWIKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTAASINGAEVEVQSWLRMSPGFSSNRDPLTQVPCENVMVRYPVPSEWVKNFRRDSVLGEKSLKAKVNRGASFGSAGASGSEPVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANYVNVEFSMPTTSASKAAVRSVSVEDKPDVRKWVNYSAHYSYKVEIEQKKSLKPDFEGEDLENPKECGVQ
What is the function of this protein?
Adapter protein involved in endocytic machinery.  Involved in the synaptic vesicle recycling.  May facilitate clathrin-coated vesicle uncoating (By similarity).
What are the official names of this protein?
Stonin-2, Stoned B.
What is the protein family that this protein belongs to?
Belongs to the Stoned B family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Synapse, synaptosome. Note=Some fraction is membrane- associated.
Protein: YFCN_SALA4
Sequence: MKKKTSLSEEDQALFRQLMVGTRKIKQDTIVHRPLRKKITEVPTRRLIQEQADASHYFSDEFQPLLNTEGPVKYVREDVSHFELKKMRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHIFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWQPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: LPXK_ACIF2
Sequence: MTLRQTLEQQWQDGGALATALRPLGALTGKVARWRRRHIQGRAASIPTIVVGNLGVGGSGKTPLVAALARQLTVAGWRVAIVSRGYGARPPHWPYRVQRDDSPQQAGDEPLLLAQEQGQTQAVYLCPDRHRAIAAAAADGYNLALLDDGFQHLALQPSLRLLVLSGPRPLGNGHCLPAGPLRECPDAMLHADALLMDAAAAAAIPERNGPPRFLFRIQPKDLVAVNDPCRSRSLDSLQGQHVTAVTGIARPQRFVASLEGLGAIPDPRFFPDHHSFCASDIAHLPRPLVMTAKDAVKCREFAQADDWTLRIEAELEASSQPWLEQSLLPWRS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: NPD_CLOAB
Sequence: MLLLDKINELKKIVAESSSIVFFGGAGVSTESNIPDFRSENGLYKTKNNFSYPPEVMLSHTFFKNHTEDFFEFYREKMIFKDAKPNAAHYSLAKIEEQGKLKAIVTQNIDGLHQLAGSKNVYELHGSIHRNYCMDCGKSFDLEYVIKSETTIPKCDKCGGIVKPDVVLYEEGLDDSIIQNSVKAISEADTLIVGGTSLVVYPAAGLIRYFKGNKLILINKSATAYDNEADLVISDSIGKVLETVI
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_HORVU
Sequence: MVLKTELCRFSGQKIYPGKGIRFIRSDSQVFLFANSKCKRYFHNRLKPAKLCWTAMYRKQHKKDIHAEAAKKRRRTTKKPYSRSIVGATLEVIQKKRAEKPEVRDAAREAALREIKERIKKTKDEKKAKKAEVTKSQKSQGGKGAVQKGSKGPKLGGGGGKR
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_STRGG
Sequence: MDLLNTLVDKGLRREPPTREEALAVLATSDDELLDVVAAAGKVRRQWFGRRVKLNYLVNLKSGLCPEDCSYCSQRLGSKAGILKYTWLKPEEASRAAAAGVAGGAKRVCLVASGRGPTDRDVDRVSKTIEAIKEENEGIEVCACLGLLSDGQADRLRSAGADAYNHNLNTSEETYGAITTTHTYADRVETVQQAQAAGLSACSGLIAGMGESDKDLVDVVFALRDLDPDSVPVNFLIPFEGTPLAKEWNLTPQRCLRILAMVRFVCPDVEVRLAGGREVHLRSMQPLALHLVNSIFLGDYLTSEGQAGQTDLDMIADAGFEVEGAGTTTLPRHRADALSGGCGTRDATAGSGCGSHEDSGAGGCGSHGGGAGCGPCGGHGEREPVAVADSAAGESVPGARTETSGAARTDLVAVRRRGAGTDLAPNA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SCPA_OCEIH
Sequence: MHEGYKVKLDTFEGPLDLLLHLINQFEIDIYDIPVAQITQQYMEYIHTMQHLELNIASEYLVMASTLLAIKSQMLLPKQELEDDLDEEYMEDPREELMQRLIEYRKYKEIAERLKEKESEDNQLYTRPPVVFEFKDIPEKITTNQTDISIFDMVGALKNMLKRKEWTEPHDTTVQRMDIPIETRMKEVLQQVQSNSDGLVFDKLFPSPTKNYIVVTFVAVLELMKDKQIYAVQERHFEELYLYSMEEST
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: HOA4_RHOJR
Sequence: MPYSADLDIRVTDSSLRDGSHAKRHQFTVEHVRSIVGALDAAGVPVIEVTHGDGLGGSSFNYGFSHTPEQELIKAAVETAERARIAFLMLPGLGVQSDIREAADNGASICRIATHCTEADISVQHFGLARELGLETVGFLMMSHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILNAVSDRVSALVAELGDDAQVGFHGHENLGLGVANSVLAVEAGALQIDGSTRRFGAGAGNTPVEAFAAVTEKLGIRTGIDTLKIIDAAEDVVRPIMDGDCQLDRLSLMMGYAGVYSSFLKHADSHARRYGVSGAEILIEAGRRKLVGGQEDQLIEIALGLADRGPAGSAVAEKKSA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 4, HOA 4, 4-hydroxy-2-keto-pentanoic acid aldolase 4, 4-hydroxy-2-oxopentanoate aldolase 4.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: YAJC_CHLPN
Sequence: MLSRIVTCFLFLLSSLPLFAEEEAAQSKNTFVQPAVMLAIAILFFYFILWRPEQKRRKAMEKRKNDLAKGDKVTAMGIIGTVDDIREHTVILNIASGKVEVLKGAISEILKPNDNKS
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ENV_MLVRK
Sequence: MESTTLSKPFKNQVNPWGPLIVLLILGRVNPVALGNSPHQVFNLSWEVTNEDRETVWAITGNHPLWTWWPDLTPDLCMLALHGPSYWGLEYQAPFSPPPGPPCCSRSSGSTPGCSRDCEEPLTSYTPRCNTAWNRLKLSKVTHAHNEGFYVCPGPHRPRWARSCGGPESFYCASWGCETTGRASWKPSSSWDYITVSNNLTSGQATPVCKNNTWCNSLTIRFTSLGKQATSWVTGHWWGLRLYVSGHDPGLIFGIRLKITDSGPRVPIGPNPVLSDQRPPSQPRSPPHSNSTPTETPLTLPEPPPAGVENRLLNLVKGAYQALNLTSPDRTQECWLCLVSGPPYYEGVAVLGTYSNHTSAPANCSVASQHKLTLSEVTGRGLCVGAVPKTHQALCNTTQNTSGGSYYLAAPAGTIWACNTGLTPCLSTTVLNLTTDYCVLVELWPRVTYHSPSYVYHQFEGRAKYKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATQQLQAAVHDDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHTGVVRDSMAKLRERLNQRQKLFESGQGWFERLFNGSPWFTTLISTIMGPLIVLLLILLLGPCILNRLVQFVKDRISVVQALVLTQQYHQLKSIDPEEMESRE
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.