PharMolix/UniProtQA huggingface dataset:
Protein: CRTC2_RAT
Sequence: MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSSHYGGSLPNVNQIGCGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYPRHIDSSPYSPAYLSPPPESGWRRMMPWGNLPAEKGQLFRLPSALNRTSSDSALHTSVMNPNPQDTYPGPTPPSVLPSRRGGFLDGEMDAKVPAIEENLVDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMSTGGSLPDLTNLHFPPPLPTPLDPEETVYPSLSGGNSTTNLTHTMTHLGISGGLGLGPSYDVPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLAHHALPTTSLGHPSLSAPALSSSSSSSSTSSPVLSAPPYPASTPGASPRHRRVPLSPLSLPAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLPTDQRLPPYPYSPPSLVIPSHPPTPKSLQQLPSQACLVQPSGGQPPGRQPHYGTLYPPGSSGHGQQPYHRPINDFSLGNLEQFNMESPSTSLVLDPPAFSEGPGFLGSEGSVSGPQDSHVLNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSASGLELGLGLEDELRMEPLGLEGLTMLSDPCALLPDPAVEDSFRSDRLQ
What is the function of this protein?
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.  Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation.  Enhances the interaction of CREB1 with TAF4.  Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway.  Regulates the expression of specific genes such as the steroidogenic gene, StAR.  Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells (By similarity).
What are the official names of this protein?
CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, TORC-2, Transducer of CREB protein 2.
What is the protein family that this protein belongs to?
Belongs to the TORC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the nucleus to the cytoplasm on interaction of the phosphorylated form with 14-3-3 protein. In response to cAMP levels and glucagon, relocated to the nucleus.
Protein: TRM82_DEBHA
Sequence: MKHPFQIITTDKSGKHLFATVKNNLQVFDLESGSLLGVWIDEVNSNTSLKKQQEEKIKVLQAQQEELTQTSEDTEQENTAPYKKQKSSVSKPIKVPKIPVPGPGAPPIYNYIRALTLSKDEKFLIGITDSDKSVIIFSIDFENTENCLTLIKRQVFPKRPCAVSTSIDDRTVVVADKFGDVYTIEIDSEAAIDEKELSPLLGHVSMLSDVKIAEHNGKQFILTGDRDEHIKVSNYPKSYIVKHWLFGHREFVSSLHIPDFNTDLLISGGGDEFVCLWNWYKNELLSKVPLRDLIQPFLTDSHLPPERFLTEDSKREISISKILTYVNPKSSEKLLIVLCENTNCVLLFELKDDFSIIHKCTLKVNYSLVDICLDQSSGTFIASKDIESGDDLLEFYQINNDSNNLEIVDRSNLSKAISTANNCEVESRDQFYPLYYINSLRKRSEH
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82, Transfer RNA methyltransferase 82.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 6PGD1_SPIOL
Sequence: MAPPTRIGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETVERAKQEGNLPLYGFHDPESFVNSIQKPRVIIMLVKAGAPVDATIKTLSAYLEKGDCIIDGGNEWYENTERREKAMEEKGLLYLGMGVSGGEEGARNGPSMMPGGSFDAYKNIEDILTKVAAQVDSGPCVTYIGKGGSGNFVKMIHNGIEYGDMQLIAEAYDVLKSVGKLSNEELKEVFAEWNRGELLSFLIEITADIFGIKDDKGEGYLVDKVLDKTGMKGTGKWTVQQAAELSVAAPTIASSLDSRFLSGLKDERVEAAKVFKAGGVEDTLSDQVVDKKKLIDDVRQALYAAKICSYAQGMNLIRAKSVEKEWDLKLGELARIWKGGCIIRAMFLDRIKKAYDRNPNLSNLLIDPEFSKEMIERQSAWRRVVCLAIGAGISTPGMSSSLAYFDSYRRERLPANLVQAQRDYFGAHTYERIDIPGAFHTEWFKLAKSKI
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating 1.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_CORGB
Sequence: MATSKILLYYAFTPLSDPKAVQLWQRELCESLNLRGRILISTHGINGTVGGDIDDCKAYIKKTREYPGFNRMQFKWSEGGADDFPKLSVKVRDEIVAFGAPDELKVDENGVVGGGVHLKPQQVNELVEARGDEVVFFDGRNAMEAQIGKFKDAVVPDVETTHDFIAEIESGKYDDLKDKPVVTYCTGGIRCEILSSLMINRGFKEVYQIDGGIVRYGEQFGNKGLWEGSLYVFDKRMHMEFGEDYKEVGHCIHCDTPTNKFEHCLNEDDCRELVLMCPDCFANVETRHCKRERCAAIAADFAEQGIDPLVTS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: GIPC1_MOUSE
Sequence: MPLGLGRRKKAPPLVENEEAEPSRSGLGVGEPGPLGGSAAGESQMGLPPPPAALRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPAAEVMFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEEALGLTITDNGAGYAFIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGHPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
What is the function of this protein?
Inhibits endothelial cell migration (in vitro).  May be involved in G protein-linked signaling (By similarity).
What are the official names of this protein?
PDZ domain-containing protein GIPC1, GAIP C-terminus-interacting protein, RGS-GAIP-interacting protein, RGS19-interacting protein 1, SemaF cytoplasmic domain-associated protein 1, SEMCAP-1, Synectin.
What is the protein family that this protein belongs to?
Belongs to the GIPC family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: Y3092_CLOBA
Sequence: MRFVIVTGLSGAGKTQATRSLEDLGYFCVDNLPPKLINKFAELCSQGDGKIDKVALVIDIRGGVFFDDLFETLNYLKENEFKYEILFLDASDEVLIKRFKESRRSHPLSPDGRVLNGIIQERSKLREIKDRADIIIDTSKYAIRDLREKMNEHYGDNIESEKQLSITVLSFGFKYGIPVDSDLVFDVRFIPNPFYIPELKQYSGNDKSVKDYVLKQEETITFVEKLQDMLEYLVPNYIKEGKRQLIISIGCTGGRHRSVAIANEIYERLNKGNYKAKIEHRDVGEDLHRGEKKL
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein CLH_3092.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CH10_THEM4
Sequence: MKVRPLGARLLIKPIQEEKRTEGGIVLPDTAKEKPMKAEVVAVGNLEDSDVDIVVGDKVIFSKYSGTEIKIEDDDYIIIDVEDILAKIED
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYG_CYPCA
Sequence: MHDAELVLKCWGGVEADFEGTGGEVLTRLFKQHPETQKLFPKFVGIASNELAGNAAVKAHGATVLKKLGELLKARGDHAAILKPLATTHANTHKIALNNFRLITEVLVKVMAEKAGLDAGGQSALRRVMDVVIGDIDTYYKEIGFAG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YCF39_NEOYE
Sequence: MTLLVIGATGTLGRQIVRRALDEGYNVKCMVRNLRKSAFLKEWGAELIYGDLKLPESILQSFCGVTAIIDASTSRLPDPYNAEKIDLDGKIALIEAAKAAKVERFIFFSILNSEKYPDVPLMNLKSQVVDFLQKSNVKYIVFSLGGFFQGLINQYAIPILDKKSVWVTGESTPIAYIDTQDAAKLVIKSLGVPSTENRTLPLVGNPAWTSAEIIKLCEKLSGQKTQISQIPIGLLKALRRITKTLQWTWNISDRLAFAEILSSGEQFTAPMDEVYSILGIDRLEVISLEKYLQEYFGKILKVLKDITYEQGQQDNEISF
What are the official names of this protein?
Uncharacterized protein ycf39.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Ycf39 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IHFB_VIBVU
Sequence: MTKSELIERLCAEQTHLSAKEIEDAVKDILEHMASTLESGDRIEIRGFGSFSLHYREPRVGRNPKTGDKVELEGKYVPHFKPGKELRERVNIG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RP33_RHIDO
Sequence: ELRLPEIARPVPEVLPARLPLPALPRNKMAKNQ
What is the function of this protein?
Non-cytotoxic peptide with immunosuppressive but without insulinotropic effects (PubMed:31639404).  Inhibits production of the pro-inflammatory cytokines TNF-alpha, but has no effect on IL-10 and IL-1beta production, when incubated with mouse peritoneal cells (PubMed:31639404).  Has no activity of stimulation of insulin release (PubMed:31639404).
What are the official names of this protein?
Rhinophrynin-33, RP-33.
What are the subcellular locations of this protein?
Secreted.
Protein: HXLR_BACSU
Sequence: MSRMDDKRFNCEKELTLAVIGGKWKMLILWHLGKEGTKRFNELKTLIPDITQKILVNQLRELEQDMIVHREVYPVVPPKVEYSLTPHGESLMPILEAMYEWGKGYMELIDIDKNVMKESL
What is the function of this protein?
Positive regulator of hxlAB expression.
What are the official names of this protein?
HTH-type transcriptional activator HxlR.
Protein: RS6_BEUC1
Sequence: MRNYELMIILDPEVDERTVAPSLDKFLSVIKTGGGSVDNVDIWGKRRLAYEINKRAEGIYAVVNLTATPDLAKELDRQLGLNEAVLRTKLIRPDAH
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: LPT_SALG2
Sequence: MNRISTTTITTITITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: HBSAG_HBVD3
Sequence: MGQNLSTSNPLGFFPDHQLDPAFRANTANPDWDFNPNKDTWPDANKVGAGAFGLGFTPPHGGLLGWSPQAQGILQTLPANPPPASTNRQSGRQPTPLSPPLRNTHPQAMQWNSTTFHQTLQDPRVRGLYFPAGGSSSGTVNPVLTTASPLSSIFSRIGDPALNMENITSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGTTVCLGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCRTCMTTAQGTSMYPSCCCTKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWYWGPSLYSILSPFLPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: YBEY_PROMP
Sequence: MYQKDLYDLQIDLVFKCNDFSNLSNHFINKSDNIIFESGFWEEVLLCWIKIILDEKDTSFPNFILYKKSFSLSLQIINDNEISSINQKWMNKSGSTDVLSFPIISDEDTTKDLNFIELGDLFISLETAFKQSLEFNHSIKKEMLWLASHGLLHLLGWEHNDDYELDNMLNFQEYLISKLD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLE_YEAS7
Sequence: MHKGKKNYPNLITSFRMNLKKIILNHDRFSHPERWKTNALLRFTFVYIKFLFDLMIIKNPLRMVGKTYRDAVTALNSLQSNYANIMAIRQTGDRKNTMTLLEMHEWSRRIGYSASDFNKLNIVHITGTKGKGSTAAFTSSILGQYKEQLPRIGLYTSPHLKSVRERIRINGEPISEEKFAKYFFEVWDRLDSTTSSLDKFPHMIPGSKPGYFKFLTLLSFHTFIQEDCKSCVYEVGVGGELDSTNIIEKPIVCGVTLLGIDHTFMLGDTIEEIAWNKGGIFKSGAPAFTVEKQPPQGLTILKERAEERKTTLTEVPPFKQLENVKLGIAGEFQKSNASLAVMLASEILHTSNILEEKIKCSSNASIPEKFIIGLQNTKWEGRCQVLEKGKNVWYIDGAHTKDSMVAASTWFRDMVRLSKRKKILLFNQQSRDANALVNNLYSSVSPEITFDDVIFTTNVTWKSGSYSADLVSMNTSQEDVEKLKVQESLVKNWNKIDDNRAKTHVTASIEEANELIETLYDEPADIFVTGSLHLVGGLLVVFDRIDVK
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.  Required for methionine synthesis and maintenance of intact mitochondrial DNA.  Involved in telomere maintenance (By similarity).
What are the official names of this protein?
Folylpolyglutamate synthase, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Mitochondrion matrix. Cytoplasm.
Protein: RL4_CORDI
Sequence: MTNLKLDVLTAEGKTDGQVELPAEIFDREASVALLHQVVNAQLAAKRQGTHSAKTRAEVSGGGRKPFRQKGTGRARQGSIRAPHFTGGGISHGPKPRDYSQRTPKKMIKAALFGALTDRARHERIHVISELVAGQTPSTKSARSFIERITDRRNVLLVVGREDVTAQKSARNLPGVHILFADQLNTYDVLYSDDVVFSVEALNTFINRASGAAQEEK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS8_SYNE7
Sequence: MAVNDPIADMLTRIRNASEARHATTVVPASRLARSIAEVLKREGFIADFEESGEGVQRHLVLSLKYKGKNQQPIIKALKRVSKPGLRVYSNRRDLPRVLGGIGIAIISTSQGIMTDRDARRQGVGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: YDIO_ECO57
Sequence: MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMRALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSAEQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAKEYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEVEESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGHNQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAIQIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK
What are the official names of this protein?
Probable acyl-CoA dehydrogenase YdiO.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: FLHC_SALTY
Sequence: MSEKSIVQEARDIQLAMELINLGARLQMLESETQLSRGRLIRLYKELRGSPPPKGMLPFSTDWFMTWEQNIHASMFCNAWQFLLKTGLCSGVDAVIKAYRLYLEQCPQPPEGPLLALTRAWTLVRFVESGLLELSSCNCCGGNFITHAHQPVGSFACSLCQPPSRAVKRRKLSRDAADIIPQLLDEQIEQAV
What is the function of this protein?
Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways (Probable).
What are the official names of this protein?
Flagellar transcriptional regulator FlhC.
What is the protein family that this protein belongs to?
Belongs to the FlhC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP2K2_CHICK
Sequence: MPAKRKPVLPALTITPSPAEGPGPGGSAEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELSIGRYPIPPPDSKELEAIFGRPVVDGAEGESHSVSPWARPPGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTQDFQEFVNKCLIKNPAERADLKMLMNHTFIKRSEVEEVDFAGWLCKTLRLNQPSTPTRAAV
What is the function of this protein?
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases.  Activates the ERK1 and ERK2 MAP kinases (By similarity).
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: CELF1_DANRE
Sequence: MNGSLDHPDQPDIDSIKMFVGQIPRTWSEDQLRELFEPYGAVYEINVLRDRSQNPPQSKGCCFVTYYTRKSALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFVGMISKKCNENDIRLMFSPYGQIEECRILRGPDGLSRGCAFVTFTARQMAQSAIKSMHQSQTMEGCSSPIVVKFADTQKDKEQKRIAQQLQQQMQQLNAASMWGNLTGLNSLGPQYLALYLQLLQQSASSGNALNNLHPMSGLNAMQNLAALAAAASATQATPTGSSALTTSSSPLSVLTSSGTPSGQPAQSAWDAYKAGSSPTSSTSSSVNPMASLGALQSLAAGAGAGLNMSSLASMAALNGGLGSGGLSNGSGSTMEALTQAAYSGIQQYAAAALPSLYSQSLLSQQNVSAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSSQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY
What is the function of this protein?
RNA-binding protein implicated in the regulation of several post-transcriptional events.  May be involved in mRNA translation activation and stability (By similarity).  Involved in the regulation of muscle-specific splicing of alpha actinin pre-mRNAs via the binding to the UR-repeat element (URE) at the branch point of the non-muscle (NM) exon.
What are the official names of this protein?
CUGBP Elav-like family member 1, CELF-1, Bruno-like protein 2, CUG triplet repeat RNA-binding protein 1, CUG-BP1, CUG-BP- and ETR-3-like factor 1, EDEN-BP/Bruno-like protein, RNA-binding protein BRUNOL-2.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HIS6_GEODF
Sequence: MLTKRIIPCLDVKGGRVVKGVQFLELRDAGDPVEIAEIYDRQGADELTFLDITASSDARDIIIDVVRRTAERVFMPLTVGGGVRTVDDIRRLLNAGADKVSINTAAVHRPEFVKEAAERFGSQCTVVAIDARRVPGEDRWEVYTHGGRNATGIDAVEWAQRMEEYGSGEILLTSMDCDGTKDGYDLSLTRSVTDAVGIPVIASGGVGNLEHFYDGFTNGGASACLAASIFHYREYTIQEAKEYLKGKGVPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_YERPY
Sequence: MKHIRNFSIIAHIDHGKSTLSDRIIQICGGLSEREMAAQVLDSMDLERERGITIKAQSVTLDYHSKDGQTYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAIRCSAKTGVGVPDVLERLVRDIPAPEGDPNGPLQALIIDSWFDNYLGVVSLIRIKNGSLRKGDKVKVMSTGQSYNADRLGIFTPKRVDRDVLNCGEVGWLVCAIKDILGAPVGDTLTLTRNPAEKSLPGFKKVKPQVYAGLFPISSDDYESFRDALGKLSLNDASLFYEPESSTALGFGFRCGFLGLLHMEIIQERLEREYDLELITTAPTVVYEVITTNQETVYVDSPSKLPALNNIEELREPIAECHMLLPQEYLGNVITLCIEKRGTQTNMVYHGKQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQTSDMVRVDVLINNERVDALALITHRDNAQYRGRDLVEKMKELIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLQKQKDGKKRMKQVGNVELPQEAFLAILHVGKDSK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: JDP2_RAT
Sequence: MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK
What is the function of this protein?
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins.  Involved in a variety of transcriptional responses associated with AP-1, such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris.  Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN.  May control transcription via direct regulation of the modification of histones and the assembly of chromatin (By similarity).
What are the official names of this protein?
Jun dimerization protein 2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_PSYWF
Sequence: MNINLTLIGQSIAFAIFVLFCMKFIWPALMGAISERQQKIADGLNAAEKAKADLASAEQSVEQELATAKAKAAALIEQANKSANQLIEEAKAQAQVEGERIRQQARESIDLEINQARESLRTQVSELAVLGAEQILKEKVDQQTHANMLNELAAKL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ATPL_CLOB1
Sequence: MDPKAFVSGMAALGAGIAALACIGAGIGTGNATGKAVEGVSRQPEASGKIMSTLVIGSAFSEATAIYGLIIALFLIFKI
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HCAF_PHOLL
Sequence: MKELIVNQEKRVSPELHYEISQFLYYEIALLDEWRFRDWLELLSEDLSYTMRTIVNAQTRDRRKSIQPPTTWLFNDNKFQLERRIARLETGMAWAEEPPSRTRHLLTNLVITETDLPDQFHVQSNYLLYRSQKERDEVFYVGKRLDCVRRNPKTDSWLICKREITLDQAVLTFHNLSVLF
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase.  Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.