PharMolix/UniProtQA huggingface dataset:
Protein: PK3C3_CAEEL
Sequence: MIPGMRATPTESFSFVYSCDLQTNVQVKVAEFEGIFRDVLNPVRRLNQLFAEITVYCNNQQIGYPVCTSFHTPPDSSQLARQKLIQKWNEWLTLPIRYSDLSRDAFLHITIWEHEDDEIVNNSTFSRRLVAQSKLSMFSKRGILKSGVIDVQMNVSTTPDPFVKQPETWKYSDAWGDEIDLLFKQVTRQSRGLVEDVPWLDPFASRRIEMIRAKYKYSSPDRHVFLVLEMAAIRLGPTFYKVVYYEDETKNMRVSTSVNGGVGIVSACTRYCVADPELLLESLAEVKHSAMTRRIRDVEDERHRQVKPNKQAKDRLETIVNLPSSQVLTREQRDLVWKFRHYLRQFPKALNKYLRSVNWVHPQEVKTALALMNDWELIEAEDALELLSSAFTHPAVRAYSVSRLLEAASPEQVLLYLPQLVQALKYEQGQQLPEEGNPVPVVSEEEGKIPSVATTPTEELEGRDMTVVTKKEARKAASGDLATFLIDYALASPKVSNYLYWHLKTEIESTKESKEEHSKMYQNIQDRLMEALVKRPDTRAQVDSLHQQQIFVEDLIILMNEAKARGGRLNESKSAEFRTMLSRAKHMLDLKGVHLPLDPSFRLSSVIPDTASFFKSEMMPAKISFKVLQPNGKADRNIPEEYTVIFKTGDDLRQDQLIQQMVRLIDIILKKGQLDLKLTPYLVLSTGVGQGFVQCIKSKPLRAIQEQYKAHKMDCIREAMKELRPGDGPFGIEPNVIDNYVRSLAGYSVIMYILGLGDRHLDNLLLCENGKLFHVDFGFILGRDPKPMPPPMKLTSEMVQVMGGVKSKQFLEFVQHVDSAYRILRRHSNVLLNLFSLMLDAGIPDIAAEPDKAIFKIEQRLRLDLSDEAATKHIFTQIESSLNAKMAMISDIIHAYKQNLM
What is the function of this protein?
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate (PubMed:11927551).  Together with bec-1, mediates the production of phosphatidylinositol 3-phosphate on intracellular vesicles and thereby regulates membrane trafficking (PubMed:11927551, PubMed:16111945).  Plays a role in endosome-to-Golgi retrograde transport of mig-14 (PubMed:21183797).  Involved in clearance of apoptotic cell corpses by phagosomes (PubMed:22272187).  Phagosome maturation requires two sequential and non-overlapping pulses of phosphatidylinositol-3-phosphate (PI3P) on the vesicle surface which mediates recruitment of sortins snx-1 and lst-4 and small GTPases rab-5, rab-2 and rab-7, downstream of dynamin dyn-1 (PubMed:22272187, PubMed:18425118).  The first pulse is initiated by piki-1, then maintained by vps-34 which also produces the second pulse (PubMed:22272187).  Required for embryonic development (PubMed:22272187).  Together with bec-1, involved in L3/L4 larval molting stage probably by regulating cuticle shedding (PubMed:11927551).  Regulates the expansion of the nucleus outer membrane (PubMed:11927551).  Involved in the secretion and localization of lrp-1 at the apical surface of hyp7 syncytium (PubMed:16111945).  May regulate endocytosis in hypodermal cells (PubMed:11927551).  May play a role in the formation of gut granules (a lysosome-related organelle) (PubMed:15843430).  Plays a role in germ stem cell proliferation during larval development (PubMed:28285998).
What are the official names of this protein?
Phosphatidylinositol 3-kinase catalytic subunit type 3, PI3-kinase type 3, PI3K type 3, Phosphoinositide-3-kinase class 3.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Nucleus outer membrane; Peripheral membrane protein. Cytoplasm. Cytoplasmic granule. Cell projection, phagocytic cup. Note=Colocalizes with rab-5 and dyn-1 at the phagocytic cup.
Protein: IF1_HAEI8
Sequence: MAKEDCIEMQGTILETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVEMTPYDLSKGRIIFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_CARHZ
Sequence: MKVLGLDVGDKKIGVALSDELGLTAQGLTVIYRTSLKKDLEEIKKIIDLHHVTEVVIGYPRNMNGTAGPRAELVKRFARELYKFTGIKPVFWDERLSTVEAEKLLISGDISRRKRKKVIDKLAATLILSGYLNYKSKN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPLA_POPTR
Sequence: MEKRDKGSSPMATMMGSRDENEDVENTTRTAETMLRLVPMALCVSALVVMLKNTQTNDYGSLSYSDLGAFRYLVHVNGICAGYSLLSAVIVAMPRASTMPRAWAFFLLDQVLTYVILAAGTVSTEVLYLASKGDTTITWSEACVSFGGFCHKALISIVITFVVVICYAALSLLSSYKLFSKYDSPVLTYPGKGIEIATFHG
What are the official names of this protein?
CASP-like protein 2A1, PtCASPL2A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 5DNU_ECOBW
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEIFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKD_SHIF8
Sequence: MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAATLGILPAGVRQTAGEILADGKPVSPYALRGIKIATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPFIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGKIVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PP274_ARATH
Sequence: MNQTPWKFKTFRDLLLKSVAERDLFTGKSLHALYVKSIVASSTYLSNHFVNLYSKCGRLSYARAAFYSTEEPNVFSYNVIVKAYAKDSKIHIARQLFDEIPQPDTVSYNTLISGYADARETFAAMVLFKRMRKLGFEVDGFTLSGLIAACCDRVDLIKQLHCFSVSGGFDSYSSVNNAFVTYYSKGGLLREAVSVFYGMDELRDEVSWNSMIVAYGQHKEGAKALALYKEMIFKGFKIDMFTLASVLNALTSLDHLIGGRQFHGKLIKAGFHQNSHVGSGLIDFYSKCGGCDGMYDSEKVFQEILSPDLVVWNTMISGYSMNEELSEEAVKSFRQMQRIGHRPDDCSFVCVTSACSNLSSPSQCKQIHGLAIKSHIPSNRISVNNALISLYYKSGNLQDARWVFDRMPELNAVSFNCMIKGYAQHGHGTEALLLYQRMLDSGIAPNKITFVAVLSACAHCGKVDEGQEYFNTMKETFKIEPEAEHYSCMIDLLGRAGKLEEAERFIDAMPYKPGSVAWAALLGACRKHKNMALAERAANELMVMQPLAATPYVMLANMYADARKWEEMASVRKSMRGKRIRKKPGCSWIEVKKKKHVFVAEDWSHPMIREVNEYLEEMMKKMKKVGYVMDKKWAMVKEDEAGEGDEEMRLGHHSEKLAVAFGLMSTRDGEELVVVKNLRICGDCHNAIKFMSAVAGREIIVRDNLRFHCFKDGKCSCGDYW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g49710.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
Protein: PYRF_HAEIE
Sequence: MTSKIIVALDYEKEAEALALVDQIDPSLCRLKVGKEMFTTLGINFVKQLHQRNFDVFLDLKYHDIPNTVARAVRSAADLGVWMVDLHASGGLRMMEEAKKILEPYGKDAPLLIAVTVLTSMEDLDLLQIGINASPMEQVLRLAHLTQRAGLDGVVCSPQEVEILRNACGEDFKLVTPGIRPIGTDFGDQRRVMTPTAAIRAGSDYLVIGRPITQADNPAEVLRSINVSIG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: MTL26_XENTR
Sequence: MLVAAAADRNKGPILEVLQQYVDPAAPKVRALEVASGTGQHCAHFAQALPNLHLVPSELDPHSRQSISAYISHWSLSNVEQPRTLDSSKSWETWGFSPNSLHLIICINMIHITEPSCTQGLFKGAGHLLMPGGVLFTYGPYSVNGILTPQSNVDFNISLKRRNPAWGIWDTSDLQNLATTCGMSLERMVDMPANNKCLIFRKK
What are the official names of this protein?
Methyltransferase-like 26.
What is the protein family that this protein belongs to?
Belongs to the UPF0585 family.
Protein: IL18_RAT
Sequence: MAAMSEEGSCVNFKEMMFIDNTLYLIPEDNGDLESDHFGRLHCTTAVIRSINDQVLFVDKRNPPVFEDMPDIDRTANESQTRLIIYMYKDSEVRGLAVTLSVKDGRMSTLSCKNKIISFEEMNPPENIDDIKSDLIFFQKRVPGHNKMEFESSLYEGHFLACQKEDDAFKLVLKRKDENGDKSVMFTLTNLHQS
What is the function of this protein?
Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.  Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-18, IL-18, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=The precursor is cytosolic. In response to inflammasome-activating signals, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.
Protein: CCA_BACHK
Sequence: MERFKKASSIIETLKQQGHEAYFVGGSVRDLIIDRPIGDIDIATSALPEEVMAIFPRHVPVGLEHGTVIVVENGEPYEVTTFRTESEYEDFRRPSSVQFVRSLEEDLKRRDFTMNAIAMTEEGEMVDLFAGQEAIQKREIVTVGNAADRFQEDALRMMRGIRFVSTLGFSLETKTKQAIETYGHLLEHIAIERITVEFEKLLTGTYCVKGLKELVETKLFSHLPYLQMSEERLLKATQYNWDSFETDIEAWAFFLYCIGEEHPSVFLRQWKFSNKKIKDIVAVLLTIRKRKEKDWDTVLLYKTGIHIAEMAERVYEAMIESYDHTSVERVQTLFQALPIKSRQEMDVTGNDLLNWASKKPGPWVAEMIQKIEEAIVQGNVVNEKECIREWLQECNLL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: NDK_COLLI
Sequence: MAANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGMKFVHASEELLKQHYIDLKDRPFYPGLVKYMNSGPIVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAQKEINLWFKPAELIDFKSCAHDWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: ULAR_SALTY
Sequence: MTEAQRHQILLDMLAQLGFVTVENVIERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTADGLYKTDMLTAMAEQKMLSVVGKLVALVDSSKIGERAGMLFSRADQIAMLITGKNANPQVLQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_BOVIN
Sequence: MPRYTVHVRGEWLAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFASVDDARFLVRRCKGLGLLDNEDPLDVALEDNEFVEVVIEGDAMSPDFIPSQPEGVYLYSKYREPEKYIALDGDSLTTEDLVSLGKGHYKIKLTPTAEKRVQKSREVIDRIVEEKTVVYGITTGFGKFARTVIPVSKLEELQFNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLGTLKQVIEVFNASCLPYVPEKGTVGASGDLAPLSHLALGLIGEGKMWSPKSGWADAKYVLAAHGLKPIVLKPKEGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHAVRPHRGQVEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKNIITTEINSATDNPMVFASRGETISGGNFHGEYPAKALDYLAIGVHELASISERRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDIEAAHRLLVEQKVWEVAAPYIEKYRMEHIPESRPVSPTAFSLEFLHKKSTKIPESEDL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
Protein: YBJL_ECO27
Sequence: MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4M_HORSE
Sequence: MLKIIIPTIMLMPLTWLSKKNMIWINTTTYSLLISLISLSLLNQPSNNSLNFSLMFFSDPLSAPLLVLTTWLLPLMLMASQHHLSKEPLIRKKLYITMLTMLQTFLIMTFTATELISFYILFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLMGSLPLLVALISIQNLTGSLNFLLIQYWNQALPDSWSNIFLWLACMMAFMVKMPVYGLHLWLPKAHVEAPIAGSMVLAAILLKLGGYGMLRITTMLNPQTSFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAVLIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERTHSRTMILARGLQTLLPLMAAWWLLASLTNLALPPSINLIGELFVVMSSFSWSNITIILMGANITITALYSLYMLITTQRGKYTHHINSIKPSFTRENALMALHMTPLLLLSLNPKIILGFTY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y109_MYCBO
Sequence: MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR
What are the official names of this protein?
Uncharacterized protein Mb0109.
Protein: CHEB3_SYNWW
Sequence: MIKVLIADDSALMRKMLKQILESDPEIQVVGAARDGEDVVIKAREYRPDVVTMDVNMPKQDGITALQYIVNEEICPVLMVSSLTQEGAMTTFEALELGAFDFVGKPGGTVSSSSDMKKVAAEIINKIRAAAQLKNRVVKRERLARGQRQPVVKKKAPPRPGREVTKAVAMGISTGGPKMIYEVVPLIPPDINAALFLVQHMPPNFTPAYVKRLNEACQIEVIEARAGIKVEPGVLYVGSGGRHLNLVKNTAGDVIIRLSSKPDHLFIPSVSVMMESVLKVFSNRTIGVLMTGMGNDGADSMVNIRQAGGITIAESEESAIVFGMPGDAIKRGGAEIVVPIWNIAREIIRAVNR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 3.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP1_HELVI
Sequence: ENFSGGCIPGYMRTADGRCKPTY
What is the function of this protein?
Causes rapid, rigid paralysis when injected into Lepidopteran larvae.  The physiological role may be to reduce hemolymph loss following injury and promote wound healing.
What are the official names of this protein?
Paralytic peptide 1, Paralytic peptide I, PP I.
What is the protein family that this protein belongs to?
Belongs to the GBP/PSP1/paralytic peptide family.
Protein: SYH_HAEIN
Sequence: MAKTIQAIRGMNDCAPTESPLWQWIEAQVRNVLNSYGYSEVRMPIVESTPLFARAIGEVTDVVSKEMYTFWDNDEQLTLRPEGTAGCVRAAIEHGWIYNNEQRLWYIGPMFRHERPQKGRYRQFHQVGVEVFGIANPEIDAELIMLTYRLWKALGIDQHVTLQLNSIGSLEARANYRSALVGFLENHQDLMSDEEKERLVRNPLRILDTKNPELQKVLDNAPKLLDYLDDESRTHFEQLCSLLDAVGIQYEINPKLVRGLDYYNKTVFEWVTSALGAQGTVCGGGRYDGLVEQLGGHATPSIGFAMGLERLVLLVQEVNPNVPAKSAVDIYVVYQGEGATLAAFELAEKVRSELPHLNTMLHCSSGNFKKQFKRADKSGATLALVIGESEVQNKQVVVKHLQGGTDQQTLDLVNIIDYLQTQF
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_STAAC
Sequence: MRRHAIILAAGKGTRMKSKKYKVLHEVAGKPMVEHVLESVKGSGVDQVVTIVGHGAESVKGHLGERSLYSFQEEQLGTAHAVQMAKSHLEDKEGTTIVVCGDTPLITKETLETLIAHHEDANAQATVLSASIQQPYGYGRIVRNASGRLERIVEEKDATQAEKDINEISSGIFAFNNKTLFEKLTQVKNDNAQGEYYLPDVLSLILNDGGIVEVYRTNDVEEIMGVNDRVMLSQAEKAMQRRTNHYHMLNGVTIIDPDSTYIGPDVTIGSDTVIEPGVRINGRTEIGEDVVIGQYSEINNSTIENGACIQQSVVNDASVGANTKVGPFAQLRPGAQLGADVKVGNFVEIKKADLKDGAKVSHLSYIGDAVIGERTNIGCGTITVNYDGENKFKTIVGKDSFVGCNVNLVAPVTIGDDVLVAAGSTITDDVPNDSLAVARARQTTKEGYRK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIL6_MOUSE
Sequence: MATQQPCRPKSKPPACHVRLPPEPPLKLKVVGLFKSSSFQVSKTIAETLKTSYPYRFEDPVIVPLQEFAWDQFLEEKKRELKGETWVYSSYVMCFVNDQLLGNAFDLKKWAQKVWDVIDVRPSALYEALTLDYATKFLKDTKHDFVYLDICIDLSPIGRLIFELYCDACPRTCTNFQVLCTGTSGFSERGTKLHYKDSIFHRVVQNGWIQGGDIVQGRGDDGESIYGPTFEDENFSIPHNKRGVLGMVNKGHHTNGSQFYITLQAAPYLDKKYVAFGQLIEGTHVLKQLELVPTENERPLLLCSIADSGVLYT
What is the function of this protein?
Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
What are the official names of this protein?
Probable inactive peptidyl-prolyl cis-trans isomerase-like 6, PPIase, Cyclophilin-like protein PPIL6.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: APIBP_ACTSZ
Sequence: MKLLKASLVALSLAASTFVYADNGLIAIITPSHDNPFFKAEADGAKQKAEELGYTTLVASHDDDANKQDQLISTAVSRKAKAIILDNAGSDVTVGALEKAKAAGVPAFLIDREINKTGVAVSQIVSNNYQGAQLSAEKFVELMGEKGQYVELLGRESDTNASVRSQGFHEIIDEYPEMKMVAQQTANWSQTEGFSRMESILQANPNIKGVISGNDTMALGAEAALKAAGRTDVIVVGFDGSDYVRDSILAGGNIKATALQPAWDQAQEAVVQADKYIRTGSTGKEEKQLMDCILIDSSNAKKLNKFSLSK
What is the function of this protein?
Part of an ABC transporter complex involved in D-apiose import (Probable).  Binds D-apiose, D-ribose and D-ribulose (PubMed:29867142).
What are the official names of this protein?
D-apiose import binding protein, D-apiose binding SBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UVRC_SALPB
Sequence: MSEIFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQHIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLSMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVAGLVSEEEYTQQVEYVRLFLSGKDDQVLTQLIARMEKASQDLAFEEAARIRDQIQAVRRVTEKQFVSNAGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRRIHVQTKPRGDRARYLKLARTNAATALITKLSQQSTITQRLTALAAVLKLPAIKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIAGITPGDDYAAMNQVLRRRYGKAIEESKIPDVILIDGGKGQLAQAKAVFAELDVPWDKHRPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSTLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRPA_PSEPU
Sequence: MRQIRSPRALRVIPLTALMLISGCGEKEQVSSATPPPDVGVYTVRAQALTLTTDLPGRTSAFRVAEVRPQVSGILQKRSFVEGAEVKLGQQLYQIDPRTYEAQLRRAEANRTSAQNLARRYETLLKTKAVSKQQYDDALAAWKQAEADYQVARIDVQYTRVLSPISGRIGRSTVTEGALVTNGQAQSLATVTQLDPIYVDVTQPITKLLGLQKALESGRLQKTGENQAEVSLTLDDGSAYPLPGTLKFSEVSVDPTTGSVTLRAEFPNPNRKLLPGMFVHALLKEGVQNAAILVPQQAISRDTRGVPSVWVVKADNTVESREIQTLRTVGNAWLISNGVTEGERIITEGVQRVRSGIAVNAVEAKNVNLVDGFAATTEASAN
What is the function of this protein?
The periplasmic linker protein component of an organic solvent efflux pump.  Involved in export of a number of low log POW compounds including hexane (log POW 3. 5), toluene (log POW 2. 5) and dimethylphthalate (log POW 2. 3).  The solvent resistance phenotype has been postulated to depend on the operon expression level.
What are the official names of this protein?
Solvent efflux pump periplasmic linker SrpA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: MEND_CHLAA
Sequence: MNVTAHIEALTHWVAAIAQSLAANGVKDVVVCPGSRSTPLALAVARHPSLRVWMHLDERSAGFFALGMARARGMPAAVLCTSGTAVANLLPAVVEANLARVPLVILTADRPPELRDNGAPQTIDQIGIFGRNVRWFVDLPTPDMALLPFLRATLGRAVGLARSAPAGPVHLNLPFREPLVPDRARMAALFSETPSAVQVTPARRMIGGAELAMLATSLVEYRRGLIIAGPDCPPDLGPLLTTLAHRLRYPILADPLSGVRYGPHVDEYTLGTYDAFLRDERFVSSYAPEVVLRFGAMPTSKPLLLYLQHHPHARQIVIDGGAGWREPTSLAREHLHVDEHWFCIALADALASSQREGPTLWLRAWVSAEQTARTIIQSHLLPQEHISEPGLFARLGSWLPAGATLFVGNSMPVRDCDTFLGPRTNPLYVVGNRGANGIDGLVSTALGLAAGQARPLVMALGDLSLLHDSNGLLAARLHRLDATILLINNDGGGIFSFLPQASETDQFELLFGTPHGVDFAPLAAMHNAHYTLATDWSAVHEALQASFTGGLHLIEVRTRRDQNVIDHRTIWPLVSNALAQAGITVAE
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.