PharMolix/UniProtQA huggingface dataset:
Protein: NUOCD_YERPB
Sequence: MTDLTTSDSLQPAWQTRDHLDDPVIGELSNRFGPEAFVVQATRTGMPVVWVKREQLLEVMSFLRKQPKPYVMLFDLHGVDERLRTHRQGLPDADFSVFYHLLSIERNRDIMLKVALSEKDLHVSTATKIFPNANWYERETWEMFGITFDGHPHLTRIMMPQSWEGHPLRKDYPARATEFDPYVLTKQKEDLEMESLTFKPEDWGMKRGTENEDFMFLNLGPNHPSSHGAFRIVLQLDGEEIIDCVPDVGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIVVPDRVNTIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKVYDVIEAITGFRMHPAWFRIGGVAHDLPRGWERLLRDFLDWMPKRLDSYVKAALQNSILKGRSVGVAAYNAKEALEWGVTGAGLRATGVEFDVRKWRPYSGYENFDFEVPVGNNGDCYDRVMLKVEELRQSLRILEQCYKNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPSVIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DPO3B_RICPR
Sequence: MLKLIVETKTLMQSLGFARSIIEKRNVIPEYANIKLSAQDGNLELSSTNMDLYLSQKIAVQVLNEGEITVATQTLSDIVRKFPDSELTLTEIEITQLEIKGQNCKFNLFTLPVSSFPAMDSIKPEVSFKISCADFAKIIESTKFSISLDETRYNLNGIYLHIKDKEFFAASTDGYRLSISWITLEEKIKNFGVILPQKSAEEILKIVKDPKNIHEDIEILLSSNKIKFICNENTILLSKLIDGTFPDYSAFIPKSSVSKLVINRKIFADSIERIAIITVEKFRAVKLSLSRKILEISAVGEARGTAKEIITASQDKESFYEYNHDESLVIGFNPQYLEDVLKAIKSDIVELYFSDISASAPVLIKFPRNPKDIFVIMPVKV
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_CLOBK
Sequence: MKKIIMTGGGTAGHVTPNLALVPELKKSGYEIKYIGSIEGIERKIIEKEGIEYFPISSGKLRRYFDLKNFSDPFKVLKGVFQAKKIIKREKPDIVFSKGGFVTVPVVIAAHLNKIPVIAHESDITPGLANKLATPYCTRVCVTFPESVKHIKGDKAVLTGTPIRRELLEGNKLEGIKLCGFKDNKPILLIIGGSLGSKIINEIVRKNLDNILSKFNIIHICGKSNLDENLENRKGYAQFEYVNEELPDLMKASDLVISRAGANVIYELLALKKPNLLIPLSKKSSRGDQILNAASFEKSGYSLVLKEEELEDKTLMKKLNYLYENRNVYINNMSKSKMDNGVKNITELIKKYTK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ZFPL1_CAEEL
Sequence: MGLCKCPKRKVTNLFCYEHRVNVCEFCLVDNHPNCVVQSYLTWLTDQDYDPNCSLCKTTLAEGDTIRLNCLHLLHWKCFDEWAANFPATTAPAGYRCPCCSQEVFPPINEVSPLIEKLREQLKQSNWARAALGLPTLPELNRPVPSPAPPQLKNAPVMHKEVPVHNNRSSTPATHLEMEDTASYSVSNNDVTFARKKNYGAESSSDTRPLLQLRDADNEENKYKRRPTMDWMRGLWRAKHGGSGVPQERASAKKIALFVIFLAVLALITIIMVMKRAGYSGEHSSDPLFDPMANPNIRVAVEDSRLPHV
What are the official names of this protein?
Zinc finger protein-like 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZFPL1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AROE_CLOPE
Sequence: MKLFGLIGEKLGHSLSPEIHNKVFKDNNIDGLYNLFSVKKDFENNIVESLKCLGVKGANVTIPYKEKVMDQLDIISHEAKVIGAVNTILIKDGKSYGYNTDYYGFGKMLERAKVNIEGNSFFVLGAGGAARSILKYLEDSKAKKIVLVSRDKEKAFKKFKDFNINFMSYGELEEINEEFALINTTPCGMYPNTNSVAVSEKVIKKFKVAVDIVYNPLETKFLKMAKDNGLKTVDGLFMLVGQGVKAEEIWNGIKVDKSTEEEIYEELKCRF
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RL30_GRAFK
Sequence: MGKIKVTKVKSAINRTKNQKLVLESLGLKKIGQTVEHDDTPNILGMVNKVKHLVSVEETK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PG142_VACCW
Sequence: MFVDDNSLIIYSTWPSTLSDSSGRVIVMPDNRSFTFKEGFKLDESIKSILLVNPSSIDLLKIRVYKHRIKWMGDIFVLFEQENIPPPFRLVNDK
What is the function of this protein?
Late protein which is a part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.  Required for the stability and kinase activity of OPG054.
What are the official names of this protein?
Core protein OPG142.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG142 family.
Protein: WN10A_ALOVU
Sequence: SGSCQLKTCWQVTPDFRTVGTLLKHKFYNATLIKAHNRNTGQVEHAHHHPHRRKSSAGELVFFEESPNFCESEPKLDSAGTRGRICNKTSPGLDNCESLCCGRGHNILRQTRQERCNCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Required for normal tooth development.  Regulates the expression of genes involved in tooth development.
What are the official names of this protein?
Protein Wnt-10a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: SYDND_GLOVI
Sequence: MRSDYCGTLRSEHIGKTVSLYGWIDGWRDHGGVIFLDLRDYTGIVQIVADPQRTPESYHLASSLRNEYVVRVEGRVSARPEHSLNPRLSTGTVEVYADTLAVLNRAETPPFAISKDEEVDEKLRLKFRYLDLRRGRMQKLLRLRHRVMQIMRRHLDERGFTEIETPVLVKSTPEGARDYLVPSRVNPGDWFALPQSPQLFKQLLMVAGFDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFLSMEEIIALNEGLVAAILQETMGLELSLPLPRLTYAEAMVRYGSDKPDTRFGLELVEVSEVFRESSFQVLSGAVAAGGKVVCLPVPGAEGITNTRVKPGGDLFEFVTQFGARGLLFARVREGGQVDTIGAFSKSLTPEIAAGMIEKTGAQPGHLLLFGAGDRTAVPTVLDYMGRLRLKMGEELGLIDPNRHNLLWVTDFPMFEWNAEEKRLEALHHPFTAPRPEDEHDLKTARALAYDIIWNGVEVGGGSLRIYRRALQERVFETIGLTEEEARAKFGFLLDAFEYGTPPHGGIAYGFDRFVMLIAGEQSIREVIAFPKTQRAQDLMLGAPSAVAERQLKELNVRSTLPPKTQG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_WOLWR
Sequence: MNDNLVCLGIITSPHGIKGAVKVKTFTEKPENISLYGKLISGDENYKIDSVSVIGDNLVIATISGVNSRNEAELLRNKKLYIERSKLPELNDEDEFYQSDLVDMEVRLKSNELYGYVKSVYNFGSGDILEILVISTKKRIMLSFTKEIFPHINIKGRYIVLNIPEFID
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_BURMS
Sequence: MPNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMG_ECOL6
Sequence: MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQWENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTNSYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTDWEQVANFAREIAHLTDKPTLK
What is the function of this protein?
Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic condition uses ubiquinone as an electron acceptor.
What are the official names of this protein?
Protoporphyrinogen IX dehydrogenase [quinone], Protoporphyrinogen IX dehydrogenase [menaquinone], Protoporphyrinogen IX dehydrogenase [ubiquinone], Protoporphyrinogen oxidase, PPO.
What is the protein family that this protein belongs to?
Belongs to the HemG family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ADAL_DANRE
Sequence: MDTEADLFYRQLPKVELHAHLNGSVSFETMEKLIKRKPHLNIEHSMTAIRRGQRRTLDECFQVFKVIHQLVDSEEDILMVAKSVIQEFAADGVKYLELRSTPREVTETGLSKQRYIETVLEAIRQCKQEGVDIDVRFLVAVDRRHGPEVAMQTVKLAEDFLLSSDGTVVGLDLSGDPTVGHGKDLLAALQKAKNCGLKLALHLSEVPSQIDETELLLNLPPDRIGHGTFLHPDVGGSDSLVDKVCKQNIPIEICLTSNVKGQTVPSYDKHHFKYWYNRGHPCVLCTDDKGVFCTDLSQEYQLAASTFGLTKEAVWILSQQAIGYTFAPEPIKQRLEKTWAELKQQILQ
What is the function of this protein?
Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine.  Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A).
What are the official names of this protein?
Adenosine deaminase-like protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: HSLO_CLONN
Sequence: MSDRLIKAVAKDGQVRIIVADTRELVNKGIKIHNCAPTAAAALGRMLTAGVIMGSMLKSDKDVITLKIDGGGEAKGVTVTSYANANVKGYIGNPSVDLEANALGKLDVGGAIGKNGSLLVIRDFGLKEPYVGNVPIYTGEVGDDIAYYFTVSEQTPTAVGLGVLVDKDLSIRKAGGVIIQMMPGADEMLADLITYRLQDLGSITSFLDSGKTIDDMLNFLFDDMDLKILEEMTPEYSCDCSREKIERALISIGEKDLKEIYNDGKTEEIVCQFCGEHYKFTNEEIGELLKNVRK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP80_SOLLC
Sequence: MSDVETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQPELFIHIIPDKANNTLTIIDSGIGMTKADLVNNLGTIARSGTKEFMEALAAGADVSMIGQFGVGFYSAYLVAEKVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGENLGRGTKMVLYLKEDQLEYLEERRLKDLIKKHSEFISYPISLWVEKTIEKEISDDEEEEEKKDEEGKVEEVDEEKEKEEKKKKKVKEVSNEWSLVNKQKPIWMRKPEEITKEEYAAFYKSLTNDWEEHLAVKHFSVEGQLEFKAVLFVPKRAPFDLFDTKKKPNNIKLYVRRVFIMDNCDELIPEYLSFVKGIVDSEDLPLNISRETLQQNKILKVIRKNLVKKCVELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSQNRAKFAELLRYHSTKSGDEMTSLKDYVTRMKEGQNDIYYITGESKKAVENSPFLEKLKKKGYEVLYMVDAIDEYSIGQLKEFEGKKLVSATKEGLKLDESEDEKKKQEELKEKFEGLCKVMKDVLGDKVEKVIVSDRVVDSPCCLVTGEYGWTANMERIMKAQALRDSSMAGYMSSKKTMEINPENSIMDELRKRADADKNDKSVKDLVLLLFETALLTSGFSLEEPNTFGNRIHRMLKLGLSIDEESGDADADMPALEDPEADAEGSKMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock cognate protein 80.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCPH1_GORGO
Sequence: MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANTNEHLPSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTSLDDDVPILLFESNGSLIYTPTIEINSSHHSAMEKRLQEMKEKRENLSPTSSQLIQQSHDNPSNSLCEAPLNISRDTLCSDEYFAGGLHSSFDDLCGNSGCGNQERKLEGSINDIKSDVCISSLVSKANNIHSSPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKIVTPDQKQAAGMSQETFEEKYRLSPTLSSIKGHLLIHSRPRSSSVKRKRVSHGSHSPPKEKCKRKRSIRRSIMPRLQLCRSEGRLQHVAGPALKALSCGESSYDDYFSPDNLKERNSENLPPESQLPSSPAQFSCRSLSKKERTSIFEMSDFSCVGKKTRTVDITNFTAKTISSPQKTGNGEGRATSSCVTSAPEEALRCCRQAGKEDGCPEGNGFSYTIEDPALPKGHDGDLTALEGSLEEMKEAVGLKSTQNRGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYSGSVKNRPTRHDVLDDSCDGFKDLIKPHEEMKKSGRGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSHHFPAAPLCRSECHLSAGPYRGTLFADQPVMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSITQHKVCASENYLLSQ
What is the function of this protein?
Implicated in chromosome condensation and DNA damage induced cellular responses.  May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).
What are the official names of this protein?
Microcephalin.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: PDXH_BRADU
Sequence: MTDTTSMKHQTPLTSGDFTAADEPFALFETWLNEAIKSEPNDPNAMALATVDPDGLPDVRMVLMKGFDTEGFVFYSHIASQKGRELAANPKAALLFHWKSLRRQVRIRGNVTPVTDAEADAYFATRPKQAQIGAWASKQSEALESRFAFEQAIAKVAAKYIIGEVPRPPGWSGWRITPVRIEFWHDRPFRLHDRIEFRRDAAGQKWSKTRMYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: EXO5_HUMAN
Sequence: MAETREEETVSAEASGFSDLSDSEFLEFLDLEDAQESKALVNMPGPSSESLGKDDKPISLQNWKRGLDILSPMERFHLKYLYVTDLATQNWCELQTAYGKELPGFLAPEKAAVLDTGASIHLARELELHDLVTVPVTTKEDAWAIKFLNILLLIPTLQSEGHIREFPVFGEGEGVLLVGVIDELHYTAKGELELAELKTRRRPMLPLEAQKKKDCFQVSLYKYIFDAMVQGKVTPASLIHHTKLCLEKPLGPSVLRHAQQGGFSVKSLGDLMELVFLSLTLSDLPVIDILKIEYIHQETATVLGTEIVAFKEKEVRAKVQHYMAYWMGHREPQGVDVEEAWKCRTCTYADICEWRKGSGVLSSTLAPQVKKAK
What is the function of this protein?
Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair.  Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage.  Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends.  Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting; however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'-directionality activity.
What are the official names of this protein?
Exonuclease V, Exo V, hExo5, Defects in morphology protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Note=Localizes to repair foci in response to DNA damage.
Protein: EABF_STRLI
Sequence: MHRGSLSRGQHVRGTRRRGAALAALAALLVATAPAQAAGSGALRGAGSNRCLDVLGGSQDDGALLQLYDCWGGTNQQWTSTDTGRLTVYGDKCLDVPGHATAPGTRVQIWSCSGGRNQQWRVNSDGTVVGVESGLCLEAAGAGTPNGTAVQLWTCNGGGNQKWTGLTGTPPTDGTCALPSTYRWSSTGVLAQPKSGWVALKDFTTVTHNGRHLVYGSTSSGSSYGSMVFSPFTNWSDMASAGQNAMNQAAVAPTLFYFAPKNIWVLAYQWGSWPFIYRTSSDPTDPNGWSAPQPLFTGSISGSDTGPIDQTLIADGQNMYLFFAGDNGKIYRASMPIGNFPGNFGSSYTTIMSDTKANLFEGVQVYKVQGQNQYLMIVEAMGANGRYFRSFTASSLSGSWTPQAASEGNPFAGKANSGATWTNDISHGDLVRDNPDQTMTVDPCNLQFLYQGKAPNAGGHYNSLPWRPGVLTLRH
What is the function of this protein?
Involved in the degradation of xylan and is a key enzyme in the complete degradation of the plant cell wall.  It has a specific arabinofuranose-debranching activity on xylan from gramineae.  Acts synergistically with the xylanases and binds specifically to xylan.  From small arabinoxylo-oligosides (ranging from arabinoxylotriose to arabinoxylohexaose), it liberates arabinose and, after prolonged incubation, the purified enzyme exhibits some xylanolytic activity as well.
What are the official names of this protein?
Extracellular exo-alpha-L-arabinofuranosidase, ABF, Arabinosidase, Arabinoxylan arabinofuranohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 62 family.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_STAAB
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGSRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSAPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLILFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTILRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK34_EMIHU
Sequence: MTQRTLHGTVLKKVRTSGFRSRMATKAGRRVINARRRKGRAKLTV
What are the official names of this protein?
50S ribosomal protein L34, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRMD_BURP0
Sequence: MDEATQSAIQFDVVTLFPEMFRALTDWGITSRAVKQGRFGLRTWNPRDFTTDNYRTVDDRPYGGGPGMVMLAKPLEAAIGAAKAAQAAQGVATSRVVMMSPQGAPLTHERVARMAAEPGVVLLCGRYEAIDQRLIDRCVDEELSLGDFVLSGGELPAMALMDAVVRLLPGVLNDAQSAVQDSFADGLLDCPHYTRPEEYEGVRVPDVLLGGHHAEIERWRRQEALRNTIAKRPDLIARARREKLLSRADEAWLASLAKEAKQAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXCR4_MOUSE
Sequence: MEPISVSIYTSDNYSEEVGSGDYDSNKEPCFRDENVHFNRIFLPTIYFIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAMADWYFGKFLCKAVHIIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKAVYVGVWIPALLLTIPDFIFADVSQGDISQGDDRYICDRLYPDSLWMVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYVGISIDSFILLGVIKQGCDFESIVHKWISITEALAFFHCCLNPILYAFLGAKFKSSAQHALNSMSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
What is the function of this protein?
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation (PubMed:8962122, PubMed:9295051, PubMed:9103415).  Involved in the AKT signaling cascade (By similarity).  Plays a role in regulation of cell migration, e. g.  during wound healing.  Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels.  Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity).  Involved in hematopoiesis and in cardiac ventricular septum formation (PubMed:9634237, PubMed:9634238, PubMed:9689100).  Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells (PubMed:9634237).  Involved in cerebellar development.  In the CNS, could mediate hippocampal-neuron survival (PubMed:9634238, PubMed:9689100).
What are the official names of this protein?
C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Fusin, Leukocyte-derived seven transmembrane domain receptor, LESTR, Pre-B-cell-derived chemokine receptor, PB-CKR, Stromal cell-derived factor 1 receptor, SDF-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction. Early endosome. Late endosome. Lysosome. Note=In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated (By similarity). In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation cluster (SMAC) (By similarity).
Protein: PETG_HUPLU
Sequence: MVEALLSGIVLGSIPITLAGSFVTAYPQYRRGDQLDLR
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NANE_STRPF
Sequence: MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLLAKAAQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMTEVDQLAALNIAVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTTLSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAITRPKEIAERFIEALKS
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.