PharMolix/UniProtQA huggingface dataset:
Protein: RS7_AMOA5
Sequence: MRKGSPKKRTLLPDPKYKDTLVTRFVNNLMKGGKKNLAYDIFYSAVDIVGDKTGESGLEVWKKALSNVFPSVEVKRRRVGGATLQVPIEVRPERRISLGIKWMLEQARLRGEKTMQERLAYEIIAASQGEGKSVKKKADMHKMAESNRAFSHFKI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TRHO_LEPIC
Sequence: MANQGDFPKRTETKKRPLHNIYGKEILRKRLEEENFSRTTLSFYRYVILENVQELRDQLYAEWEILGVLGRIYIAREGINAQLSIPSHNLDFFRKNLDSRNQFKDMQFKIAVEDDSKSFLKLDLKIKKKIVADGLNDDAFDVTNVGKHLSAEEFNLHMEDENSIVVDVRNHYESEIGHFENAILPQSDTFREELRILLELLNGKENHKILMYCTGGIRCEKASAWLKHHGYKDVNQLHGGIISYAHEVSQKGLESKFKGKNFVFDGRLQEAIGNEVISSCHQCGAKCDRHVNCENPGCHVLFIQCPSCSEKFEGCCTLECQNVLHLPKEKQKEIRKGKLNENRFFSKSKIRPKISELYHGILFKSSK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: SPRTL_STRR6
Sequence: MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLDFNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLPNSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_CHLP8
Sequence: MKVYSSIKKRCEHCRIIKRKGKRYVICKVNPSHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: MATA_NEUCR
Sequence: MSGVDQIVKTFADLAEDDREAAMRAFSRMMRRGTEPVRRIPAAKKKVNGFMGFRSYYSPLFSQLPQKERSPFMTILWQHDPFHNEWDFMCSVYSSIRTYLEQEKVTLQLWIHYAVGHLGVIIRDNYMASFGWNLVRFPNGTHDLERTALPLVQHNLQPMNGLCLLTKCLESGLPLANPHSVIAKLSDPSYDMIWFNKRPHRQQGHAVQTDESEVGVSAMFPRNHTVAAEVDGIINLPLSHWIQQGEFGTESGYSAQFETLLDSILENGHASSNDPYNMALAIDVPMMGFNGGA
What is the function of this protein?
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion.  Transcriptional activator that induces the transcription of A-specific genes like mating factor ccg-4.  Required for mating as an A-cell and for blocking of heterokaryon formation (vegetative incompatibility).
What are the official names of this protein?
Mating-type protein A-1, Mt A-1.
What is the protein family that this protein belongs to?
Belongs to the MATALPHA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURA_CLOBJ
Sequence: MSAFIVLGAQWGDEGKGKMTDYLAENADVVVRFQGGNNAGHTVVVGEKEYKLHLIPSGILYNDKLNVIGNGVVLDPKALFEEINYLESLGVEITPDRLIISDRAHVIMPYHRILDGIKERARGNKDIGTTGKGIGPSYTDKMERSGIRVCDLIHKEVFEENLKETLEVKNKIITEIFGGEALDYNEIYNEYLGYAEKLRPFVKDISVIVNKKIKDGKEVLFEGAQGTLLDIDYGTYPYVTSSSTIAGGVCIGAGVGPTAITNAVGIAKAYTTRVGKGPFPTELLDSTGDWVREKGHEFGVTTGRARRCGWLDLVILKTSARISGLTSFAVTKIDTLAGLDTLKVCTGYRLNGEIIDYVPASLEDLAKCEPIYEEFEGWDDSIANARCYEDLPENAIKYLKKIEDFTETKVSIVSVGPKRDQTMMISEI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMP_BACAN
Sequence: MLSEKTIEIVKSTVPLLQEKGVEITTRFYEILFSEHPELLNIFNHTNQKKGRQQQALANAVYAAATYIDNLEAIIPVVKQIGHKHRSLGIKAEHYPIVGTCLLRAIKEVAGAPDEVLNAWGEAYGVIADAFISIEAEMYEEAAHKEGGWKDFRNFVVVKKVKESDVITSLYLKPEDGGKVSSFIPGQYVTVQINIEGETYTHNRQYSLSDAPGKEYYRISVKKEKGVDTPDGKVSNYLHDHVKEGDMLPVSAPAGDFVLNMDSTLPVVLISGGVGITPMMSMLNTLIEQDSKRNVCFVHAAINSNTHAMKEHVEAVDNEYEQVKAYTCYSAPTEKDLEMKNFDKEGFVEREWLQTIIPTTEAEFYFCGPVPFMKHINAVLTDLGVKQEHIHYEFFGPAASLQ
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: ATPD_STRPB
Sequence: MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTNLDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIAIVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNKVIDTSIRRQLQAFKMNLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CGGR_PRIM3
Sequence: MRSLIEVQRKLLPELLSVMQKRYQILQYIRLMQPIGRRNLAVSLGLTERVLRSEVTFLKEQDLIDIYPSGMTLTNEGELLLAELEEVMKEVSGLRLLETTLKEAFSLSEVVVVSGDSDQSPWVKNEMGRASVSCIKERLVGKKNTVAVTGGTTLAAVAEMMTPDLKHPDVLFVPARGGLGENVQNQANTICAKMAEKSMSHYRLLHVPDQLSDEAYRSIIGEPSIKDMLHLIKSAGMVVHGIGDAMTMAERRKTPQADLEKVKNGHAVGEAFGYYFNHQGEVVHKVKTVGIQLDDLKNNKCVIAVAGGSSKAKAIKAFMQQAHDSILITDEGAAKELVRDFN
What is the function of this protein?
In the absence of glucose, represses the transcription of the gapA operon, which encodes five key glycolytic enzymes.
What are the official names of this protein?
Central glycolytic genes regulator.
What is the protein family that this protein belongs to?
Belongs to the SorC transcriptional regulatory family.
Protein: ATPG_ECO7I
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARO1_PENRW
Sequence: MSEPTKISILGRESIVADFGLWRNFVAKDLISDLSSTTYVLVTDTNLGSLYTPTFQKTFEAAAASITPAPRLLIHHVAPGESSKSRQTKADIEDWMLSQNPPCGRDTVIIALGGGVIGDLIGFVAATYMRGVRFVQVPTTLLAMVDSSIGGKTAIDTPLGKNLIGSIWQPSRIYIDLEFLETLPVREFINGMAEVIKTAAISSEEEFTALEDNADLILAAVRSEPKAGQGRFGGIRDILKARILASARHKAFVVSADEREGGLRNLLNWGHSIGHAIEAILTPQILHGECVAIGMVKEAELARHLGILKGVAVARVVKCISAYGLPTSMKDARVRKLTAGKHCSVDQLLFNMALDKKNDGPKKKVVLLSAIGRTHEPKASVVSNDDIGVVLAPSVEVHPGVPKSLNVTCAPPGSKSISNRALVLAALGSGTCRVKNLLHSDDTEVMLNALERLGAATFSWEEEGEVLVVNGKGGKIIASPTPLYLGNAGTASRFLTTVATLATPSSVDSSVLTGNNRMKQRPIGDLVDALTVNGAGVEYMESKGCLPLKIAASGGFAGGKINLAAKVSSQYVSSLLMCAPYAKEPVTLKLVGGKPISQPYIDMTTAMMRSFGIDVKKSTTEEHTYHIPQGHYVNPAEYIVESDASSATYPLAIAAVTGTTCTVPNIGSKSLQGDARFAVDVLRPMGCSVVQTDTSTTVTGPTDGVLQPLPDVDMEPMTDAFLTASVLAAVAQGKGANHTTRIYGIANQRVKECNRIKAMKDELAKFGVICREHDDGLEIDGIERSSLRQPSGGVFCYDDHRVAFSFSVLSLIAPQSTLILEKECVGKTWPGWWDALKQMFSVNLNGKELAEAEHAASSDEKRSSASVFIIGMRGAGKTTTGNWVAKALDRRFIDLDTELETSEGMTIPDIIKTRGWEGFRDAELAVLKRVLKDHPTGYVFACGGGVVEMPEARKLLTDYHKSKGNVLLIMRDIKLVMDFLQIDKTRPAYVEDMMGVWLRRKPWFQECSNIQYYSQHSTSTELALASEDFTRFMRVVTGQVDSLSLIKKKKHSFFVSLTLPDVEPSGDIITEACVGSDAVELRVDLLKDPAVDGDIPSIDYVNEQMSLLRRRTTLPVIFTIRTKSQGGRFPDDAHDAAMQLYRLAFRCGCEFVDLEIAFPDAMLRAVTEMKGYSKIIASHHDPKGTLSWANMSWIPSYNRALEYGDVIKLVGVANTLDDNNALRKFKTWAEEAHDVPLIAINMGDSGQLSRILNGFMTPVSHPSLPFKAAPGQLSAAEIRRGLSLMGEIKAQKFAIFGSPVSGSRSPALHNTLFAKMGLPHDYSRLETTKVEDVKDFIRAPDFGGASVTIPLKLDIMPLLDEVAQEAEIIGAVNTIVRVSNGNNPPRLIGYNTDWQGMIRCMRNAGVYGSTGSQSAVVIGGGGTARAAIFALHNMGFSPIYVVGRTASKLESMVSTFPTNYNIRVVDNRAQLDTVPQVAIGTIPADRPIDPVMRETLCHMFERAQEIDGTLIGKSSDTSKHRVLLEMAYKPAVTALMQLASDAGWSTIPGLEVLVGQGVHQFVHWTGITPLYHEARVSKHLDYFLSF
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_RICTY
Sequence: MNIFNQLKQDIIAASQQLYNNQEIANTATIETPKDSFNGDLSSNIAMIIASKESIAPREVALKFKEVLVTLPYIASIEIAGPGFINFTIKAESWQAAIKDILQHEEKFFEIDIDKNSNINIEYVSANPTGPMHIGHARGAVYGDVLARILQKVGYSVTKEYYVNDAGSQINDLVSTVLLRYKEALGEQITIPIGLYPGEYLIPLGEILSKEYGNKLLTMNDVERFKIIKSLAVEKMLDLNRKDLADLGIKHDIFFSEQSLYDKGEIEKTVKLLESMGLIYEGTLPAPKGKVHEDWKHKVQKLFKSTNYGDSQDRPIEKADGSWSYFASDLAYAKDKIDRGANHLIYVLGADHSGYVKRIEAIVKALGQEKVKVDVKICQLVNFVENGVPVKMSKRLGSFASVQDVNKKVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTKSILSKARELMPEAYNSFKEGKYNLSLLSTEEEIEIIKLLAAWTKTLEASVKYFEPHRIAFYLINLASKFHSMWNFGKENSDYRFIIENNQELTLARLALASVIQKVIASGLEVIGVEPMVTM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_ROSDO
Sequence: MRFQTELVPARLTRRYKRFLADCVLDADGAEITAHCANPGSMMGLAAPGTRIWLEPNDDPKKKLKFGWRLVDHENGHFTGVDTSLPNRVLKEALVARHVETLSGYGTVRPEVKYGQNSRIDFLLSEDGLPDAYVEVKSVTLSRQTGQAEFPDSVTARGAKHLQELADMAQAGHRAIMLYLVQRTDCTSFTLAGDIDPTYAAAFRSARDRGVETLCLGTNITPQGIEVAGAIPIRL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RLMN_BRUA1
Sequence: MSISFDLTIDDTRDQLARHARASLEAKPSLIGMSREEMAAALIAAGVPERQVKMRISQLWHWLYVRGVSDFADMRNISKDLRAMLAQHFTIARPEVVEEQISQDGTRKWLFRFPPRGAGRPVEIESVYIPEEGRGTLCISSQVGCTLTCSFCHTGTQKLVRNLTSEEILAQLLTARDRLGDFPDKDTPDGAMVPAEGRKITNIVMMGMGEPLYNFEEVKKALLIASDGDGLSLSKCRITLSTSGVVPEIYRTGDEIGVMLAISLHAVRDELRDILVPINKKYPLAELIKACREYPGLSNAKRITFEYVMLKDINDSLDDAKLLVKLLQGIPAKINLIPFNPWPGTNYQCSDWEQIEKFADYVNAAGYASPIRTPRGRDILAACGQLKSESERLRKSERLALEAMMIAGHGE
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_STRTD
Sequence: MTVTVKMLVDKLKLKVVYGNEELLAKAITTADISRPGLEMTGYFDYYSPERLQLVGMKEWSYLKTMTANNRYSVFANIFREETPAVVVARGLEIPEEMLQAAKENGVAVLQGRNSTSSLSGDMSWYLNSQLAERTSVHGVLVDIYGMGVLIQGDSGIGKSETALELVKRGHRLVADDRVDVYAKDEGTLWGEPAEILLHLLEIRGVGIIDVMSLYGASAVRDSSQVQLCICLEHFENDEVFDRLGNSNEEIELQGVKIPRIRIPVKTGRNVSVVIEAAAMNYRAKQMGYDATKTFKDRLTDLISKNGED
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: NUPP_BACSU
Sequence: MVKRLSHLLVPLIAIILGLAAGALIMLVSGYSVASGYSALWNGIFGEIYYVGETIRQITPYILSGLAVAFAFRTGLFNIGVEGQLLVGWTAAVWVGTAFDGPAYIHLPLALITAAAAGGLWGFIPGILKARFYVHEVIVTIMMNYIALHMTNYIISNVLTDHQDKTGKIHESASLRSPFLEQITDYSRLHLGIIVALLAAVIMWFIINKSTKGFELRAVGFNQHASQYAGMSVRKNIMTSMLISGAFAGLAGAMEGLGTFEYAAVKGAFTGVGFDGIAVALLGGNTAVGVVLAACLLGGLKIGALNMPIESGVPSEVVDIVIAIIILFVASSYAIRFVMGKLKKKGAN
What is the function of this protein?
Part of an ABC transporter complex involved in the uptake of guanosine (PubMed:21926227).  Responsible for the translocation of the substrate across the membrane (Probable).  May be a nucleoside transporter of broad specificity but with various affinities for different substrates (PubMed:21926227).
What are the official names of this protein?
Guanosine ABC transporter permease protein NupP.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDPC_BACFR
Sequence: MKTLLKSIKITLVFCVFFSVFYILVLWLFAQVAGPNRGNAEVVTLNGKVVGAANVGQTFTEEKYFWGRPSCAGDGYDATSSAGSNKGPTNPEYLAEVEARIDTFLIHHPYLARKDVPAEMVTASASGLDPDITPQSAYVQVKRVAQARGMDVEEVRRVVDKAVEKPLLGIFGTEKVNVLKLNIALEELKNR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y453_YERE8
Sequence: MSDSLWHLYLLRTTSGMLYTGITTDVARRLTQHQAGKGAKALRGKGELALVFHCEAGDRSTALKLEYRVKQLSKQQKEKLVMNQPSSLVSLLDVRTD
What are the official names of this protein?
UPF0213 protein YE0453.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: GLGC_STRSV
Sequence: MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALSNCANSGIHNVGVITQYQPLALNSHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGTSHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEASRFGIMNTDANNRIVEFEEKPENPKSTKASMGIYIFDWQRLRNMLVAAEKSNVDMSDFGKNVIPNYLESGESVYAYDFAGYWKDVGTVESLWEANMEYISPENALDSRNRRWKIYSRNLISPPNFISENSHVEDSLVVDGCFVDGTVKHSILSTGAQVKKGAVIEDSVIMSGAVIGKDAKIKRAIIGEGAIISDGVEIDGTEEVYVVGYNEKVGVPKDED
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: VPS38_SCHPO
Sequence: MSLELPGNYRLSRLKSIQIRNVQEIQNHSKFAINTTENLWKRDVQLKRAISEGTIRIFISLHVQSKKLPVYITETSGNANHIFYVDEKVTEKLQKYRHEEYFIVRTWCSSSSHAFKLHKEWKILRYDSNFRYIGNDPVFAVCHIRNGLLCEFNDGVYIYTTSQSSDIMRQTSFPKSASTYSIDRRKDGYTIQKITRILKLAECIDEMHIAKHEIRAHFQEEEFQQIRLMHKRMLLRDEKIDELAKLEHLWQKQINSITQMRTKFDKTKSWLSSKRNTLNKSKESLQKDEAEYVELANSLKTKVETNIEIRILMAHAIRMHVSHLSKIYPIQPSPGNHDEFTIRNLRLSFEPDKINNVEMAASIGFLAHLLQTLSKYLEKELAYPILCASSRSSILDTLTPDIPTRIFPLYPATRPIELFEHAIYLLNQDVNDFLETFGLPIDQSMDILRNFKKLLQFILSGQHLSFVQVTSTAP
What is the function of this protein?
Involved in endosome-to-Golgi retrograde transport as part of the vps34 PI3-kinase complex II.  Mediates the interaction between atg6 and the pik3-ppk19 core complex, leading to the recruitment of atg6 to the membrane (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 38.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: Y872_RICPR
Sequence: MKFLIEDNIKFMQQFSIYHTSNELFLKAILRLIEKCYYSNFKSVILTTDVHQQEMLNKNLWTYSRKQFIPHGSKFDPQPAKQPIYITDELQNPNNASVLVIISPTDIAKILQVKEYIKVFKRIIIITDLLENLKELIIKINKFTGQENKIDCFTQNPIGTWNKIA
What are the official names of this protein?
Uncharacterized protein RP872.
Protein: VF93L_ASFB7
Sequence: MFFFGIFRCNMDHWTTKRQVYIYLCFSLMTIALICYLIHICCHTKKNVVTNALPSNNMALIPYTPSNNMALIPYTPSNNTVPPPYTISGSCPQ
What are the official names of this protein?
Uncharacterized membrane protein KP93L/DP93R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus KP93L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: HIKES_CHICK
Sequence: MFGCLVAGRLVQAAPQQVAEDKFVFDLPDYENINHVVVFMLGTVPFPEGMGGSVYFCYPDQSGMAVWQLLGFVTNEKPSAIFKISGLKSGKGSQHPFGAMNLPQTPTVAQIGISVELLENLVQQTPVANAAVSSVDSFTEFTQKMLDNFYNFASSFAVTQAQMTPNPSEAFIPANVVLKWYENFQRRLTQNPLFWKT
What is the function of this protein?
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus.  HSP70 proteins import is required to protect cells from heat shock damages (By similarity).
What are the official names of this protein?
Protein Hikeshi.
What is the protein family that this protein belongs to?
Belongs to the OPI10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: FMT_RICSI
Sequence: YFSYNDKIIKILEAEYLNADHHCTSGTVISDKLEIACGSGILRVKKLQQESKKALNIEEFLRGTNILKDTVLK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RL10E_PYRFU
Sequence: MALRPAKIDRYVDKPAYTRREYIRGAPGPKITIFDMGNPAGDFEFEVSLHTAEPVQIRQNALEAARQQVNRYLQKNVGRSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARLKKDQKILSIRVNRQHLKFAIEGARRAAMKFPCKCYYRIYDKEGNDVTTKILSQSL
What are the official names of this protein?
50S ribosomal protein L10e, Large ribosomal subunit protein uL16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SPCS1_HUMAN
Sequence: MARGGDTGCTGPSETSASGAAAIALPGLEGPATDAQCQTLPLTVLKSRSPSPRSLPPALSCPPPQPAMLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQESSTDDKKPGERKIKRHAKNN
What is the function of this protein?
(Microbial infection) Required for the post-translational processing of proteins involved in virion assembly and secretion from flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), Dengue virus type 2 (DENV-2), Yellow Fever virus (YFV), Zika virus (ZIKV) and hepatitis C virus (HCV) (PubMed:24009510, PubMed:27383988, PubMed:29593046).  Plays a key role in the post-translational processing of flaviviral structural proteins prM, E, and NS1 (PubMed:27383988, PubMed:29593046).  In HCV, it is involved in virion assembly where it promotes the interaction between HCV virus proteins NS2 and E2 (PubMed:24009510).
What are the official names of this protein?
Signal peptidase complex subunit 1, Microsomal signal peptidase 12 kDa subunit, SPase 12 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PERR_RAUSE
Sequence: MPRVKLGTQGLEVSKLGFGCMGLSGDYNDALPEEQGIAVIKEAFNCGITFFDTSDIYGENGSNEELLGKALKQLPREKIQVGTKFGIHEIGFSGVKAKGTPDYVRSCCEASLKRLDVDYIDLFYIHRIDTTVPIEITMGELKKLVEEGKIKYVGLSEASPDTIRRAHAVHPVTALQIEYSLWTRDIEDEIVPLCRQLGIGIVPYSPIGRGLFAGKAIKESLPENSVLTSHPRFVGENLEKNKQIYYRIEALSQKHGCTPVQLALAWVLHQGEDVVPIPGTTKIKNLHNNVGALKVKLTKEDLKEISDAVPLDEVAGESIHEVIAVTNWKFANTPPLK
What is the function of this protein?
Aldo-keto reductase involved in the biosynthesis of monoterpenoid indole alkaloids.  Broad substrate specificity enzyme with a high selectivity in the group of alkaloids.  Can use perakine, 19(S),20(R)-dihydro-peraksine-17,21-al, cinnamic aldehyde, p-coumaric aldehyde and 3-(3,4,5-trimethoxyphenyl)propanal as substrates, but not ketosteroids such as progesterone.  NADPH could not be replaced by NADH.
What are the official names of this protein?
Perakine reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: Y3617_XANOM
Sequence: MPAARQQRGAGVEAAARALLEQAGLRLVVGNANYRGGELDLVMRDGQSLVFVEVRYRRDDRFGGGAASVDWRKRRKLVLAAQLFLGAHPALAALPCRFDVVDASGEPPVLHWIRDAFRADDC
What are the official names of this protein?
UPF0102 protein XOO3617.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: FUCO_BRAFL
Sequence: MGLLLLLSLLSACFQPRYAPTWDSLDQRPLPSWYDEAKFGIFMHWGVFSVPSFGSEWFWWDWKGAHDQNFIKDFMKRNYPPGFRYADFAPMFTAEWYNPLQWAEVLQASGAKYVVLTSKHHEGFTNWPSKYSWNWNSVDNGPHRDLVGELAMAIRNNSDLHFGLYYSLFEWFHPLYLKDKQNKWTTQDYTKDVGLAELYELVNAYHPEVVWSDGDWEAPYTYWNSTNFLAWLYNDSPVKDTVVTNDRWGSGMLCHHGGYYTCSDRYNPGVLQKHKWENCMTIDKKSWGFRREATLADYLDMDDLVKILAETVSCGGNLLMNIGPTHDGRIVPIFEERLRSMGKWLQVNGDAIYATKPWRAQNDTRESGVWYTSKNDSVYAIVLDWPNSGQLTLGVPRSSPTTTVTMLGWAAPLKWVAVSGSGITVQMPTASSNQLPCQWAWVIRMKGVM
What is the function of this protein?
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
What are the official names of this protein?
Alpha-L-fucosidase, Alpha-L-fucoside fucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 29 family.
What are the subcellular locations of this protein?
Secreted.