PharMolix/UniProtQA huggingface dataset:
Protein: MDHM_FRAAN
Sequence: MRPSMSLIRSVSRVARRGYSSESVPQRKVAVLGAAGGIGQPLALLMKLNPLVSQLSLYDIAGTPGVAADVSHINTRSEVKGYAGEEQLGEALEGCDVVIIPAGVPRKPGMTRDDLFNINAGIVRSLTAAIAKYCPHAIINMISNPVNSTVPIASEVLKKAGVYDEKKLFGVTTLDVVRAKTFYAGKAGVPVAEVNVPVVGGHAGITILPLFSQATPKANLSDDYIKALTKRTQDGGTEVVEAKAGKGSATLSMAYAGALFADACLXGLNGVPDVVECSYVQSSITELPFFASKVRLGKNGVEEVLDLGPLSDFEKEGLKQLKPELKSSIEKGIKFANQS
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GLYA_XANOP
Sequence: MFSRDVRLETYDPELAKAIAAEAGRQEDHVELIASENYCSQLVMEAQGSQLTNKYAEGYPGKRYYGGCAFVDIAEQLAIDRIKQVFDADYANVQPHSGSQANQAVYLALLQPGDTILGMSLAHGGHLTHGAKANVSGKLFNAVQYGVNEQGLIDYDEVQRLATEHTPKMVVAGFSAYSQKIDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGGIIVAKGASEELQKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAFKTYQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITVNKNAVPNDPRSPFVTSGLRLGTPAITTRGYKEPDSIDLANWIADVLDAPTDEAVLAKVRDAVTAQCKRYPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLPL3_MOUSE
Sequence: MYDPERRWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTRSRASKDDHRMLKHGHHPSPHKPQGNSAGL
What is the function of this protein?
Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids.  Does not esterify other lysophospholipids.  Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA (PubMed:22560221).  Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides (By similarity).  In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety (By similarity).  However, the triacylglycerol hydrolase activity is controversial and may be very low (PubMed:22560221).  Possesses phospholipase A2 activity (By similarity).
What are the official names of this protein?
1-acylglycerol-3-phosphate O-acyltransferase Pnpla3, Acylglycerol transacylase, Adiponutrin, ADPN, Calcium-independent phospholipase A2-epsilon, iPLA2-epsilon, Lysophosphatidic acid acyltransferase, Patatin-like phospholipase domain-containing protein 3.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Lipid droplet.
Protein: RS6_YERPS
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYSATITNAAGTIHRLEDWGRRQLAYPINKLHKAHYVLLNVEAPQEAIDELETNFRFNDAVIRSMVMRVKHAVTEASPMVKAKDERRERHDFASEANDDSEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: AROA_BACVZ
Sequence: MKREKVTSLNGEIHIPGDKSISHRSVMFGALAEGTTTVKNFLPGADCLSTIACFRKMGVSIEQNGSDVTIYGKGIDALCEPDSLLDVGNSGTTIRLMLGILAGRPFHSTVAGDESIAKRPMKRVTEPLKQMGAAIDGRADGGFTPLSVRGGQLKGIDYVSPVASAQIKSAVLLAGLQAEGTTTVTEPHKSRDHTERMLNAFGAELAETETSASVTGGQKLRGADIFVPGDISSAAFFLAAGAVVPGSRIVLKNVGLNPTRTGMIDVLKQMGASLEVIPSEADSAEPYGDLVIETSALKAAEIGGEIIPRLIDEIPIIALLATQAEGTTVIKDAAELKVKETNRIDTVVSELRKIGADIEPTEDGMKIHGKKTLAGGADVSSHGDHRIGMMLGVASCLTEEPIDIRDTEAIHVSYPTFFEHLDQLAKKA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_SYNS3
Sequence: MKVRASVKKMCEKCRVIRRHGRVMVICPNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SPEE_ECOHS
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDALASQPS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP8_LATCH
Sequence: MPQLNPSPWLLILLFSWLIFLTMLPSKTQLHTFPNMPSTQNMCKQEPEPWTWPWA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: ZG52_XENLA
Sequence: TAENPFTCPECGKRFSQKSNCWHTEDHTGEKPFTCMECSKSFTVKSSLLSHQRVHTGEKPYTCTQCNKQFSHSAQLRAHISTHTGVGPFPCTECSKTFSLKHKLYKHQRIHTGEKPFQCLECGKSFSVKHGLLKHQRSHTGEKPYACSECQKTFAHKTTLMVHERIHTGERPYECNDCGKRFIHSTNLNCHQKIHSGEKPFTCTECGKSFSLKNKLVRHQKIH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Gastrula zinc finger protein XlCGF52.1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQD3_SCHPO
Sequence: MTESIISSRTASISSKEGYEIRQGSTDSSSLDLEKKENAVDTTIAKPFDSDEDIADVEKAGGKKINNSLIDETFAFMQDAKKLDPLTPKQESKLKWKLYIYLLLMLGFLDMMLFIGKATLSYSTILGLFDDVHITSNQYNNLNTLFYVGYIVGQFPGHYIMQTFPLGKFVGLVTFSWSVIVFLHCCAYNYGGLIALRFFLGFTESCLLPAMEATMGMFFTHQEQAFLQPVFWISCLSCGIPAGFIAYGLEFVTKSIAPWKLFMIITGGITFFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKSTRGGIENKIFKKHQFIEALKDPITWLFTFAAFTLMLSNNLAYQQNLIFTSLNVSDLNSTLVGVALAGYNTVSAIIATFAMYLIPNQSAYHAMFWMLPSITGGIAFVALPWSNRIGELATMIIASDFGITYIIALGWTTATSTGYTKKLTRGLMFMVGYAIANIISPQLWQSRDAPRYYPAWIVQIVVAWFVTPIIYLVARVILARRNKQRKELKDKKIAEGSLETIEKTYVDTVDEFGNPVKVLIDNSMLDLTDMENLNFVYPL
What are the official names of this protein?
Uncharacterized transporter PB1C11.03.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Allantoate permease family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Protein: YCIB_AFIC5
Sequence: MDKRVPHPLFKLATELGPLLIFFAANAKFNLFVATGAFMVAIVAAVIVSYVVMRHVPLMALVTAVIVLVFGGLTLVLHDETFIKIKPTIIYALFAVTLYVGLMLGRSFIAILFDQVFNLTPEGWRFLTIRWARFFLFMAVLNEVIWRTQSTDFWVAFKAFGVIPLTAVFAMTQMPLVKRYQIAEATAEASDSERGDTSPR
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: H2B1_RAT
Sequence: MPEPAKSRPAPKKGSKKAVTKAQKKDGKERKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGERRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Has broad antibacterial activity.  May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid (By similarity).
What are the official names of this protein?
Histone H2B type 1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DGDG2_LOTJA
Sequence: MGKKQHIAIFTTASLPWLTGTAVNPLFRAAYLSKDGERDVTLVIPWLSLKDQALVYPNNITFASPSEHEKYIRQWLEERVGFTSGFSIKFYPGKFSRDKRSILAVGDISEVIPDKEADIAVLEEPEHLTWFHHGKRWKTKFRLVIGIIHTNYLEYVKREKNGQMQAFLLKYLNNWVVGIYCHKVIRLSAATQDYSGSIVCNVHGVNPKFLEIGKKKREQQQNGDQAFTKGAYFIGKMVWSKGYKELLHLFKNHQKELSALEVDLFGSGEDSDEVQKAAKKLEMAVRVHPARDHADALFHDYKLFLNPSTTDVVCTTTAEALAMGKIVVCANHCSNEFFKQFPNCWTFDESKGFVQLILKALAEEPAQLTDAQRHDLSWEAATERFLKAAELDKPFEKKLSRSTSIYMSTSLNLQQTVDDASAYVHHVASGFEISRRMFGAIPGSLKPDEELSKELGLSDSGRK
What is the function of this protein?
Involved in the synthesis of diacylglycerol galactolipids that are specifically found in thylakoid membranes.  Specific for alpha-glycosidic linkages.
What are the official names of this protein?
Digalactosyldiacylglycerol synthase 2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Symbiosome, peribacteroid membrane. Plastid, chloroplast outer membrane.
Protein: ISPF_PSEP1
Sequence: MRIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRALLRHVVGIVKAKGWKVGNVDATIVAQAPKMAPHIETMRQLIAEDLQVELDQVNVKATTTEKLGFTGREEGIAVHSVALLLPA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: MENG_RENSM
Sequence: MSRASLDKRPDEVAAMFDDVAPKYDVTNDVLSMGQTRRWRRLVVDAVGAVPGQRVLDVAAGTGTSSEPYADAGLDVVALDFSLGMLKVGKRRRPDIDFIAGDATALPFADNSFDAVTISFGLRNVNEPKKALAEMLRVTKPGGKLVVAEFSHPTFGPFRTVYTEYLMRALPAIANRSSSNPSAYVYLAESIRAWPDQDNLAQWIADVGWSDVSYRNLNGGLVALHRAFKEGKLEAKP
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: CH601_SORC5
Sequence: MAAKQIVFSRGARAAILKGVNTLADAVKVTLGPKGRNVVIEKSWGSPVVTKDGVTVAKEVELAGKLENMGAQMVREVASKTSDKAGDGTTTATVLAQAIFGEGLKLVEAGHNPMDLKRGIDAAVAKVIEAVQKAAKPTKDKDQIAQVATVSANGDKEIGQILADAMEKVGKEGVITVEENKRMTTELETVDGMQFDRGYLSPYFVTDPEKMTAVLTNPLILVHEKKISAMADLLPLLEQVVKQGRELLILSEDVEGEALATLVVNKLRGTIKVAAVKAPGFGDRRKDMLKDIAILTGATPFMEDLGQKLESATVRDLGTAKRVEIDKDNTVIVDGQGDKTAIKGRIEAIRKQIADTTSDYDREKLQERLAKLAGGVAVVKVGAATETEMKEKKARVEDALHATRAAVEEGIVVGGGVALFRAAASLESLKFNDERDVGVRLVRRAVEAPLRQIAQNAGVDGTVVAEKVRSGAPTFGYNAATDSYEDLLAGGVIDPAKVVRHAISNAASVAALMLTTEALVAEKPKKEKAAAGGAPGGMGGMGGMGGMGGMGGMGGMGDFDMG
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALS7_CANAL
Sequence: MKKLYLLYLLASFTTVISKEVTGVFNQFNSLIWSYTYRARYEEISTLTAKAQLEWALDGTIASPGDTFTLVMPCVYKFMTYETSVQLTANSIAYATCDFDAGEDTKSFSSLKCTVTDELTEDTSVFGSVILPIAFNVGGSGSKSTITDSKCFSSGYNTVTFFDGNNQLSTTANFLPRRELAFGLVVSQRLSMSLDTMTNFVMSTPCFMGYQSGKLGFTSNDDDFEIDCSSIHVGITNEINDWSMPVSSVPFDHTIRCTSRALYIEFKTIPAGYRPFVDAIVQIPTTEPFFVKYTNEFACVNGIYTSIPFTSFFSQPILYDEALAIGADLVRTTSTVIGSITRTTTLPFISRLQKTKTILVLEPIPTTTVTTSHHGFDTWYYTKKATIGDTATVFIDVPQHTATTLTTYWQESSTATTTYFDDIDLVDTVIVKIPYPNPTIITTQFWSGKYLTTETHKEPPLGTDSVIIKEPHNPTVTTTEFWSESFATTETITNNPEGTDSVIIKEPHNPTVTTTKFWSESFATTETITTGPLGTDSIVIHDPLEESSSSTAIESSDSNISSSAQDSSSSVEQSFTSADETSSIVELSSSSDIPSSSIGLTSSESSTVSSYDSYSSSTSESSIASSYDSYSSSSIESSTLSSSDRYSSSISDTTSFWDSSSSDLESTSITWSSSIDAQSSHLVQSVSNSISTSQEISSSSSEESSTSATDALVSSDASSILSSDTSSYYPSSTISPSDDFPHTIAGESDSQSFSFITSTVEISSDSVSLTSDPASSFDSSSRLNSDSSSSPSTDQRDILTSSSFSTLIKSSESRESSSGTILSEESSDSIPTTFSTRYWSPSGMSSRHYTNSTETSVSDVVSSSVAGDETSESSVSVTSESSESVTSESVASESVTSESVTAVSDISDLYTTSEEVSTSDSNSGMSSPIPSSEQRSSIPIMSSSDESSESRESSIGTILSEESSDSIPTTFSTRYWSPSGMSSRHYTNSTETSVSDVVSSSVAGDETSESSVSVISESSESVTSESVASESVTAVSDISDLYTTSEVVSTSDSKIVPSTSVPSSEQRSSIPIMSSSDESSESRESSSGTILSEENSDSIPTTFSTRYVSVSLTVGELSALPSLPGKLSHLPSSLSETSIGMTKSANLSPQFFSTSVDSALSYWASGSSSADHQSSATCDVSESSVEGNLSAMALGMSNSDDGLSEDTRSSSVAGKEEIELTSTNSVGEITLISYSSSSPTTHDHGRVSKSMGAAPLSSLFSVSVHAPLVTGLSDSDTFPSENSNRSRSFKESTDNTISISRESLGNPYSSISSPSDYDVKSFTTSRELVSSESILPFSDVMDANDMPTSGSNLHSMVFSISVLGEKFNANIEKHKNTNGHYSSMVFTYQSAGLEESDQRIAVTNTKFDQNKIDTTIDSNTFVTSLPFATTLNDQIDQAVPIKIPASSTAGFVSDVLKPDYSKSVQAESVQTDSTTYSEMMSSKRNKNSGFGTSSLNLKPTITVVTKSIDTKVNTMKEGGVSKQVSTTVTEQYDTSTYTPASLLVSDNSGSVSKYSLWMMAFYMLFGLF
What is the function of this protein?
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation.  Plays an important role in the pathogenesis of C. albicans infections.
What are the official names of this protein?
Agglutinin-like protein 7, Adhesin 7.
What is the protein family that this protein belongs to?
Belongs to the ALS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer.
Protein: Y5078_DROME
Sequence: MVYESGFTTRRTYSSRPVTTSYAVTRTKRTPIDWEKVPFVPRPSLISDPVTAFGVRRPDLERRQRSILDPINRASIKPDYKLAYEPIEPYVSTRDKNRTRILGMVRQHIDTVEAGGNTAGRTFRDSLDAQLPRLHRAVSESLPVRRETYRNERSGAMVTKYSY
What are the official names of this protein?
Uncharacterized protein CG45078.
Protein: G1PDH_METTH
Sequence: MDPRKIQLPREIYTGPGVIEDTGRICRDLRFEGRAMVVTGPRTLQIAGEAAIESLQAEGFEVDQVTVDDATMASVRNVQDGLDGVSVVLGVGGGKVIDVAKMSATLEGLHFISVPTAASHDGIASPRASIRNGEGTASLEASSPIGVIADTEIISRAPFRLLASGCADIISNYTAIMDWKLAHRLLNERYSESAAALSLMTAKMIIKSADAIKEGLEESARLAVKSLISSGIAISIAGSSRPASGSEHKFSHALDMIAPKPALHGEQCGVGTIMMMHLHGGDWQFIRDALARINAPTTAAELGIDPEYIIEALTMAHNIRRERYTILGDRGLTREAAERLAKITEVI
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.  Is also able to catalyze the reverse reaction, i. e.  the NAD(P)(+)-dependent oxidation of G1P but not of G3P.  Is not active toward glycerol, dihydroxyacetone, glyceraldehyde-3-phosphate, glyceraldehyde and glycerol-2-phosphate.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMP_BPT5
Sequence: MNQVKTNITRNFPHISRVMIWDLDGTIINSFHRVAPCFDSEGNLDLNKYKNEACKHDLIMQDTLLPLVTYMRQCMNDANTLNIICTARLMSKSDYYYLRKQGLRGRGDSNIRVFSRDTLHKYFEADKVSEIYHSKDAVYKSYYFGLFKQLYPNADFTMIDDHKGVLSAAASYGFKTLDAQAVNDILSIGVTLIGETFIDESLEDDNDYQFLADRLQLCWEGMTEEERAEYSCSPQQYIEKLKVA
What is the function of this protein?
Following host DNA degradation, is responsible for the degradation of 5'-dNMP's to deoxynucleosides that can be further excreted (PubMed:335083).  Active on deoxynucleoside 5'-monophosphates but not active as a phosphatase on ribonucleotides, deoxynucleoside 5'-triphosphates, deoxynucleoside 3'-monophosphates, or deoxyoligonucleotides (PubMed:21305).
What are the official names of this protein?
5'-deoxynucleotidase, Deoxynucleoside-5'-monophosphatase, 5'-dNMPase, Protein dmp.
Protein: CASK_BUBBU
Sequence: MMKSFFLVVTILALTLPFLGAQEQNQEQPIRCEKEERFFNDKIAKYIPIQYVLSRYPSYGLNYYQQKPVALINNQFLPYPYYAKPAAVRSPAQILQWQVLPNTVPAKSCQAQPTTMTRHPHPHLSFMAIPPKKNQDKTEIPTINTIVSVEPTSTPTTEAIENTVATLEASSEVIESVPETNTAQVTSTVV
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2652_LEPCP
Sequence: MLFLLSPAKSLDYQTPTRVAATEPLYTRQAADLIEILRTKTPVEVAELMDLSDALAGLNVARYAAWQPQADRHNSKPAVLAFNGDVYDGLDARTLATPDLRWAQSHLVILSGLYGALRPLDALQPYRLEMGTRLANPQGPDLYAWWGDTVSDYLNERQSGEPHPVVVNLASQEYFKVVRRGVLKARVVDCVFEDWKGGVYKIISFHAKRARGLMARYAITQRIRRVADLQGFDLAGYAYAPAVSGPDRLVFRRHPAD
What are the official names of this protein?
UPF0246 protein Lcho_2652.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SECA_THISH
Sequence: MVTSLVRKIFGSRNERIVKRLGKTVARINELEAELQSLDDEALKARTGQLRERLAGGESLEALLPEAFAVTREAGRRVMGMRHFDVQLIGGMVLDSGRIAEMRTGEGKTLVATLAAYLNALSGKGVHVVTVNDYLARRDAAWMGRLYHALGLSVGVINSSGGAGPDSASYLYDPGFHAEGGIAHLRPVTRREAYAADITYGTNNEFGFDYLRDNMAFRLEDRVQRELNFAIVDEVDSILIDEARTPLIISGPAGESAEMYERMNRIVPKLTPQEEEEGPGDYSVDEKMKQVFLTEDGQEKAEQLMRDAGLLAEGQGLYDAGSIALLHHLNAALRAHILFHKDVDYLVRDGQILIIDEFTGRIMAGRRWSEGLHQAIEAKEGVPIQRENQTLASITFQNYFRLYEKLSGMTGTADTEAYEFQQIYGLEVVVIPTNRPMVRNDMQDLVYMTQKEKFEAIIKEIKYCQEKRQPVLVGTASVETSEYLSGLLKKAKIAHEVLNAKQHEREAHVVEQAGRPGAVTLATNMAGRGTDIVLGGSLEAELATLGDNPKPADVDRVKADWQKRHDEVLANGGLHIIGSERHESRRIDNQLRGRAGRQGDPGSSRFFLSLEDNLMRIFASDRVKSLMQRLGMQEGEAIENAWVTKAIENAQRKVEAHNFDIRKNLLEYDDVANDQRKVVYEQRRELLETEDISETLEAVRRDVLEGVISQYIPQGSIEEQWDVPGLTHVLEQDFGLVLDIAGWLEREDDLHEETLRERIHQHAAEAYQVKEDKVGAETMRRIEKDVMLQVLDSHWKEHLAAMDYLRQGIGLRGYAQRNPKQEYKREAFEMFEALLTRIKHDVTALLMRVQVRSPEDAEALERQQRAAAGADMRFQHSQPESVLHKPEAGEGEEAQPFRRETPKVGRNDPCWCGSGKKFKHCHGKL
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: NFI_ECOSM
Sequence: MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLAWVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRYTANQP
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_CHLFF
Sequence: MKKNYYALAYYHFTRVDNPQEEIALHKELFKKLDVSCRIYISEQGINGQFSGYQPDAEYYMNWLKQRPGFSNVKFKIHHIEENIFPRATVKYRKELVALGCDVDLSNQGKHISPKEWHEKLEENRCLVLDVRNNYEWKIGHFENAVLPDIQTFREFPEYAEQLSKEHDPETTPVMMYCTGGIRCELYSSLLLEKGFKEVYQLDGGVIAYGQAMGTGKWRGKLFVFDDRLAVPIDEADTDVSPIAQCSHCEASCDTYYNCANTDCNNLFICCEECIHSTKGCCSQECSQAPRIRSFSTSRGNKPFRRMHLCEISEEQEKPLSCCLR
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: KPRS_BUCAI
Sequence: MPDMKLFSGNSIPKLAKFIANRLYINLGKASVGRFSDGEISVQINENVRGSDVFIIQSTCSPTNDNIMELVVMVDSLRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSIGVDRVLTVDLHAEQIQGFFDVPVDNVFGSLILLEDMLQRELKNPIVVSPDIGGVVRARAIAKLLYDTDMAIIDKRRPRANVSQIMNIIGDVANRDCILVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPVFSGDAPKNLKNSVIDEVVVCDTIPLSENIELLPNVRTLTLSGMLAEAIRRISNEESISAMFEH
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.