PharMolix/UniProtQA huggingface dataset:
Protein: GATY_ECO5E
Sequence: MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKHYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: PFS2_YARLI
Sequence: MSSDSGPLHRRTIPISVHIFSGFFYAPFYAPQLTQFIVTITMYSTYQRPAGYQPRQQPQGEEDRRPAHRRTVDHGSAFGKWHLDRLSGRTIQPANMRSEQSYIVDLLPPSAYTNINGSLRSTNPHITSVAATPAKFIQVALNKVRHPVYSATWTPDGRRLLTGSMSGEFTLWNGMTFNFESIMQAHESGVRSLKYSHSGEWLLSGDHEGNVKFWQPSLNCVNVIDKAHRESIRELAFAPSDHKFVTGSDDGLLKIWDFHESSNAESVLKGHGWDVKSVDWHSELGLIVSGSKDNLIKLWDPRSAKNVNTFHGFKNTVMKTTFQPTGTKRLLAAGCRDRTCRILDLRMLNSGSSEAGPTAGTDMPTRGDRSMAVLRGHDSDVFSLTWHPTHANVVTSGTKTGSIYTFNVDTTPAGGAYGPDSGILPVNTIPSAHDYCVSTLDYHPEGHVLCSGGLDRMTRFWARPRPGDPTSFRDKYYEPKEEGVSVKTLPGVNNATSRAGMARVEHVSTQHFNTAQPEVTDDEPVSIPGFAR
What is the function of this protein?
Required for 3'-end cleavage and polyadenylation of pre-mRNAs.  Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).
What are the official names of this protein?
Polyadenylation factor subunit 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CO5A1_RAT
Sequence: MDVHTRWKAPRPGAPLLSSPLLLLLLLLWAPPPSRAAQPTDLLEMLDFHNLPSGVTKTTGFCATRRSSKEPDVAYRVSKDAQLSMPTKQLYPESDFPEDFSILTTVKAKKGSQAFLVSVYNEQGIQQLGLELGRSPVFLYEDHTGKPGPEEYPLFPGINLSDGKWHRIAISVYKKNVTLILDCKKKITKFLNRGDHPIIDVNGIIMFGSRILDDEIFEGDIQQLLFVSDHRAAYDYCEHYSPDCDTAVPDTPQSQDPNPDEYYPEGEGETYYYEYPYYEDPEDPGKEPAPSQKPVEAARETTEVPEEQTQPPSEAPTVPETSDTAGKEDNPGIGDYDYVPTDDYYTTSPYEDFGYGEGVENPDQPTNPDSGAEIPTSTSVTSNSSNPAPSPEEGKDDLGGEFTEETIKNLDENYYDPYFDPDSDSNVSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTTGPTGQMGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPMGPPGSGGLKGEPGDMGPQGPRGVQGPPGPTGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGLPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPTGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGAAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGSEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGVPGEEGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPTGQPGPSGADGEPGPRGQQGLFGQKGDEGSRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPLGPKGERGEKGEAGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPLGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGLPGPPGPPGEVIQPLPIQASRTRRNIDASQLLDDGAGESYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGSTCVFPDKKSEGARITSWPKENPGSWFSEFKRGKLLSYVDAEGNPVGVVQMTFLRLLSASAQQNITYNCYQSVAWQDAATGSYDKAIRFLGSNDEEMSYDNNPYIRALVDGCATKKGYQKTVLEIDTPKVEQVPIVDIMFTDFGEASQKFGFEVGPACFLG
What is the function of this protein?
Type V collagen is a member of group I collagen (fibrillar forming collagen).  It is a minor connective tissue component of nearly ubiquitous distribution.  Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin (By similarity).
What are the official names of this protein?
Collagen alpha-1(V) chain.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: DER_BACC3
Sequence: MPKPVIAIVGRPNVGKSTIFNRIVGERVSIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAIDEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRSDIYDFYALGFGEPFPISGTHGLGLGDLLDEAAQHFPKIEEDGYDEDTIRFSLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYSKDGKDYVIIDTAGMRKKGKVYESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEENIRAHFQFLEYAPIVFLSAKTRKRTQTLIPVIDEVNESHSIRIQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVNDPELLHFSYERFLKNRLRESFGFVGTPIHIIARARD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: OPSD_GAMAF
Sequence: MNGTEGPYFYVPMVNTTGIVRSPYEYPQYYLVSPAAYACLGAYMFFLILVGFPVNFLTLYVTIEHKKLRTPLNYILLNLAVADLFMVFGGFTTTIYTSMHGYFVLGRLGCNLEGYFATLGGEIGLWSLVVLAVERWLVVCKPISNFRFTENHAIMGLVFTWIMANACAAPPLLGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVIYMFICHFCIPLVVVFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVVILVIGFLVCWTPYASVAWYIFSNQGSEFGPLFMTIPAFFAKSSSIYNPMIYICMNKQFRHCMITTLCCGKNPFEEEEGASTTASKTEASSVSSSSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (PubMed:18422881).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: CBIMQ_METLZ
Sequence: MHIMEGFLPSPWWQFWALLAVVCVLAGMAALIRLVKRNPESLPLLGLAGACVFILSSLKLPSVGSSSHATGTGFGAILFGPAVCSVFCTIVLVFQALLLAHGGITTLGANIISMGVAGPLAACIIFKIGHLIRPEFSIRSFSVTVFCAAAAADLVTYMMTSLQLALAYPAAEGGVLASFVVYLGIFSITQVPLAVLEGILIVLMMRFVIRIRPDIFVSLDILSKKETRILLPSSDQNLSPISKNKWIIAGIIVVLLTASLAFLLAGLGLQSGSDDLVAETLIDLGNLPVFDPLNLVSEDMHGWLFALQAGIGAAVLVFCLYLLRIRSASRGFGKKPHTIFDEHILDDVAIASPLRQVSAWLKLLFCLSAIIIGVTSPLPYLPLFIAGVMIFAALIIAKVSPRLYGSLLTIPLVFAGTGAAVILLITGGGETLIDFFRIGAFHFQITTTSLELAALVLSRTLAGMCSLYFLTLTTPITSLFSVLQKMRMPQAFIDLSMLIYRYIFVFIGEAIAIHNAQIMRGGYGTWKNYLTSFSMLASMLFIRTWEKGEAIFVSMDSRCYDGCMALPEEEGHVTPLSAMAVFLFIALIFGLLCAEMLLL
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Putative fused cobalt transport protein CbiMQ, Energy-coupling factor transporter probable substrate-capture protein CbiMQ, ECF transporter S component CbiMQ.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the CbiQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABZ_BACAN
Sequence: MLDIQQIKEIIPHRYPFLLVDKVLEVEEGKRAIGIKNVTANEEFFNGHFPDYPVMPGVLIVEALAQVGAVAMLKKEENRGRLAFFAGIDNCRFKRQVRPGDQLRLEVEMTRVRGAIGKGKAIATVDGEIACETEITFALGDKKE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP18_HUMAN
Sequence: MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC
What is the function of this protein?
Has enzymatic activity similar to isoform 1 and interferes with type I interferon signaling.  Major deISGylation enzyme for nuclear proteins (PubMed:22170061).
What are the official names of this protein?
Ubl carboxyl-terminal hydrolase 18, 43 kDa ISG15-specific protease, hUBP43, ISG15-specific-processing protease, Ubl thioesterase 18.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Cytoplasm.
Protein: DUT_SYNC1
Sequence: MKTITIKVKRLHSKAMLPAYMSPHAAGMDLYACPDGEVVVKPGCRTIVPTGIALAIPVGYEGQVRPRSGLALHHGVTLVNTPGTIDADYRGELGIIIINHGDEDFVVSPGDRIAQLVIAPVHRAVLETVEELDETDRNEGGFGHTGF
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: H2BE2_PSAMI
Sequence: MAPTAQVAKKGSKKAVKAPRPSGGKKRNRKRKESYGIYIYKVLKQVHPDTGISSRAMIIMNSFVNDIFERIAGESSRLAQYNKKSTISSREIQTAVRLILPGELAKHAVSEGTKAVTKYTTSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.2, embryonic.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS13_SYNAS
Sequence: MARIAGVDLPKNKRMEIALTYIYGIGRTKAKEILEKAEISFDTKTDELADSEINAIRTIIDRDHKVEGDLRRDISMSIKRLMDVGAYRGLRHRKGLPVRGQRTHTNARTRKGPRRAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SYV_SPHAL
Sequence: MPMEKTFDPAAIEAKWARLWESRGLFRPHRPDATPFTIVNPPPNVTGALHIGHALDNTLQDVLIRYERLRGKDALWVVGTDHAGIATQMVVERQLNERQQKRTDFTRDEFVDKVWEWKATSGGQITRQLRRLGCSMDWSREQFTMDPHFTRAVVKVFVDLHKKGLIYRDKRLVNWDPKLKTAISDLEVETHEVQGGFWHFKYPLADGVKLDDGHDHIVVATTRPETMLADMAVAVHPDDARYKSVIGKFVELPITGRRVPVVADEHADPELGSGAVKITPGHDFNDFEVGKRAGFKPAEMLNMFDGDANVIQTADGLIPAEYLGLHRFKRDGIDGARELVVQRMKETGFLIPHTDKDGNAHDAEPRTIQTPFGDRGGVVIEPWLTDQWYVDAEKLAQAPIQAVRDGRIQIVPKTWEKTFFNWMENIQPWCVSRQLWWGHRIPAWYAEDGRTFVAETEEEAQAEAGAGVILTRDPDVLDTWFSSALWPFATLGWPDDTELLKRHYPNDVLISGFDILFFWDARMAMQGMEFMGEVPWRTLYLHGLVRAPDGQKMSKSKGNVVDPIGLIDQYGADALRFFMCAMESQGRDIKMDDARLAGYRNFATKLWNAARFCEANGIAASTSLEAPAATLPVNRWIIGEVADTVAAVEAAFAAYRFDDAANAIYSFAWDRFCDWYLELIKPVLSQKPSPLQGRGLGEGDEAVPAPADGPLSPALSPEGEREIAETRAVAGWVLDQILVMLHPFMPFITEELWTGLGDRADYPLITAKWPAPNAARDAAASADIDWLIKLVSELRTAKAELGLPPGARLTAHFPASLKDRADKLAAQLDRLARLETISFDPAPAGASAQLVVEGETITIPLEGVIDIAAERERLTRALAAATKERDSLAGRLNNPSFVERAKPEAVEKARTDHAAKEAEADRLSAALARLG
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_XANC5
Sequence: MTSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQEDVEPNKRKDLGLHAALKSVFPISSYSGNAALEYVGYKLGQPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTGNGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYSNEEMLAEFFEINTFHINPDEGVQLELVPERLRGETLNFDLADGDKVIVEAGKRITARHVKQLEAAGVAALAVPDDYLVGRILSHDVVDGSTGELLANANDEINEDQLAAFRKAGVDAVGTLWVNDLDRGPYLSNTLRIDPTKTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFERYDLSTVGRMKFNRRVGRKDVLGESVLYDKKYFAERNDEESKRLVAEHADTSDILEVIKVLTEIRNGRGVVDDIDHLGNRRVRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVFALGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVFARTNQYGFLETPYRKVLDGKVSDDVEYLSAIEENEYVIAQANALTDAKNMLTEQFVPCRFQGESLLKPPSEVHFMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPTLRSQKPLVGTGIERAVARDSGVTVNALRGGVIEQIDAARIVVKVNEAEIGGGTDAGVDIYNLIKYTRSNQNTCINQRPLVNVGDVIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEISADIPNVSEQALNRLDESGVVYIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDVQVFTRDGIEKDKRARQIEENEIKRVKKDFDDQFRILEAAIYARLRSQIVGKVANGGANLKKGDTVTDAYLDGLKKSDWFQLRMKDEDAADAIERAQKQIQAHEKEFEARFADKRGKITQGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVVPVEDMPYMATGESVDIVLNPLGVPSRMNIGQILEVHLGWAAKGLGRKIQRMLEAQAAVSELRKFLNDIYNHDNAINAQRVDLSQFSDEELLNLGKNLIDGVPMATPVFDGASEAEIKRMLELADLPQSGQTQLYDGRTGEAFDRKTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAGMPESFNVLVKEIRSLAINMELEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TTRA_SALTY
Sequence: MANLTRRQWLKVGLAVGGMVTFGLSYRDVAKRAIDGLLNGTSGKVTRDRIFGNALIPEAQAQTHWQQNPQQTIAMTQCFGCWTQCGIRARVNADGKVIRIAGNPYHPLSQEHPIDSSVPFSEAMEQLAGESGLDARSTACARGATLLESLYSPLRLLEPMKRVGKRGEGKWQRISFEQLIEEVVEGGDLFGEGHVDGLRAIHAPDTPIDAKHPSFGPKTNQLLVTNTSDEGRDAFLRRFALNSFGSKNFGAHGAYCGLAYRAGSGALMGDLDKNPHVKPDWENVEFALFMGTSPAQSGNPFKRQARQLASARLRENFQYVVVAPALPLSTVLADPRGRWQPVMPGSDSALAMGMIRWIMDNQRYNADYLAIPGVQAMQQAGEQSWTNATHLVIADELPTLAGQHLTLRHLTPDGEETPVVLNTDGELVDASTCRQARLFVTQYVTLADGQRVTVKSGLQRLKEAAEKLSLAQYSEQCGVPEAQIIALAETFTSHGRKAAVISHGGMMAGNGFYNAWSVMMLNALIGNLSLSGGVFVGGGKFNGVSDGPRYNMNSFAGKVKPSGLSIARSKTAYEASEEYRDKIAGGQSPYPAKAPWYPFVAGQLTELLTSALEGYPYPLKAWISNMSNPFYGVPGLRAVAEEKLKDPRRLPLFIAIDAFMNETTALADYIVPDTHNFESWGFTAPWGGVASKATTARWPVVAPATHRTADGQPVSMEAFCIAVAKRLHLPGFGDRAITDPQGNTFPLNRAEDFYLRVAANIAFMGKTPVALANQEDISLTGVSRILPAIQHTLKADEVGRVAFIYSRGGRFAPEDSGYTEQRLGNAWKKPLQIWNADVAAHRHAITGERFSGCPVWYPARLSDGRAIDDQFPIGQWPLKLISFKSNTMSSSTAVIPRLHHVKPANLVALNPQDGERYGLQHGDRVRIITPGGQVVAQISLLNGVMPGVIAIEHGYGHREMGATQHSLDGVPMPYDPQIRAGINLNDLGFADPTRTITNTWLDWVSGAAVRQGLPAKIERI
What is the function of this protein?
Part of a membrane-bound tetrathionate reductase that catalyzes the reduction of tetrathionate to thiosulfate.  TtrA is the catalytic subunit.  During mice infection, the ability to use tetrathionate as an electron acceptor is a growth advantage for S. typhimurium over the competing microbiota in the lumen of the inflamed gut.
What are the official names of this protein?
Tetrathionate reductase subunit A, Tetrathionate reductase molybdenum subunit.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm. Cell inner membrane; Peripheral membrane protein; Periplasmic side.
Protein: FOLD_RHOPT
Sequence: MTARIIDGKTISAEVRARVAAEVTRLKTDHGITPGLAVVLVGNDPASEVYVRSKHKQTQEAGMASFEHRLPADVPQAELMALIAKLNADPAVHGILVQLPLPKGLDSNAVIDAIDPAKDVDGLNPTNAGRLASGLFALTPCTPLGSIIMAKTVHASLEGMNALVIGRSNLVGKPLVQLLLNENATVTIAHSRTRDLPALCRQADLVFAAVGKAEMVKGDWIKPGATVIDVGINRTPGKDGGKDKLLGDVAFAEAKEVAGAITPVPGGVGLMTVACLLVNTVRAACAIHGLPKPAV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: YCZK_BACSU
Sequence: MGGLQTTGYAENASFSQLSACFSSRLVREDLFLMFSAYNQFTLLHSRLTMISYNGDDQ
What are the official names of this protein?
Uncharacterized protein YczK.
Protein: ST17B_MOUSE
Sequence: MSRRRFDCRSVSGLLTTTPQTPIKTENFNNFYTLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWLQQWDFGSLFHPEETSGSSQIQDLTLRSSEEKTSKSSCNGSCGAREDKENIPEDGSLVSKRFRFDDSLPSPHELVPDLFC
What is the function of this protein?
Acts as a positive regulator of apoptosis.  Phosphorylates myosin light chains (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane.
Protein: UBACT_TERXR
Sequence: MPDQRQQERSRRKQGEPSPLPTPTRHDPPPSEQESPVRRMLRDLRERDPGQEAEEEAAQRRQQRREQSGE
What is the function of this protein?
May function as a protein modifier covalently attached to lysine residues of substrate proteins.  This may serve to target the modified proteins for degradation by proteasomes.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein UBact.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-like protein UBact family.
Protein: HTPX_SALEP
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLLIMALLFGFGGSFISLLMSKWMALKSVGGEVIEQPRNERERWLMNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRIIAQIAAGFLGGNRDEGEGSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRSGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOZ_LACP7
Sequence: MLHPSYNDLMQVVNSEVEPGEQPVVNSRYSIVLATAKRARQIIDGAEPLTESSCNKPLSIAVEELYKSKVKIVSEDDENENE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: COAA_MYCSJ
Sequence: MARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELKKLRGLGEKLDLLEVEEVYLPLARLIHLQVAARQRLFAATSEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWGNHARVDLVTTDGFLYPNAELGRRNIMHRKGFPESYDRRALMRFVTAVKSGADYACAPVYSHLLYDIVPGEKQVIRHPDILILEGLNVLQTGPALMVSDLFDFSVYVDARLEDIEGWYISRFLTMRSTAFADPASHFHHYATLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDADHAINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_VIBVY
Sequence: MKTWQYQYQLFCLAVSFFSRLPVPKSTPYSDERMNQAGRYFALVGTLLGLLCVLVYAFASLFFPYQVAIVLMMAFSLLLTGAFHEDGLTDMADGIGGGMTLDKRLTIMKDSRIGTYGSATLTMALIGKFVFLTTLARQPDFGLMIVVAYTLSRAVAATLIYDMPYVSDSDTSKSKPLANAQSSTELAILILTGVLAAISLGLGVGLLLILFAILFRWAFKRWLLARLGGFTGDCLGGAQQLMELGIYLVLIAVVQ
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARPC4_MOUSE
Sequence: MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF
What is the function of this protein?
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 4, Arp2/3 complex 20 kDa subunit, p20-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC4 family.
Protein: SHE2_VANPO
Sequence: MAETANNGELQNVTLKDIFEQIKEVFSTYISSYVHILNKFIGILRKVSTMRFERSTLIKYVKKLRFFNETLLNYEFPLLTSSDITTVRLQVKAIGSFFIKFLEMQDILNYYLTQSVQNEVISKTLNYKLNFPDAAIERIEDSYNHFVKFTQWMMQSLLIDDELSQIEVIQFSIKCAVEDNVDLTQTTNIFLQEVAPVESLAEYMELSEEWVAILKDLIARMENEFSLAVVQWTEATEKKK
What is the function of this protein?
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease.  Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell (By similarity).
What are the official names of this protein?
SWI5-dependent HO expression protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHE2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm and is exported in an mRNA-dependent manner. The presence in the nucleus is essential for PUF6 and LOC1 to bind the ASH1 mRNA.