PharMolix/UniProtQA huggingface dataset:
Protein: LEU1_VARPS
Sequence: MTDQLIIFDTTLRDGEQSPGASMTRDEKMRIAKQLERLKVDVIEAGFPASSNGDFEAVKAIADIIKESTVCGLSRANDRDISRAAEALKGAARGRIHTFIATSPLHMEKKLRMSPDEVHEQAKLAVRFARNLVSDVEFSPEDGYRSDPDFLCRVLETVINEGATTINVPDTVGYAIPELYGNFIKMLRERVPNSDKAIWSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNCSLEEVVMAVKTRRDYFGLDLNIDTTHIVAASRMVSQTTGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWAANKIVLGKLSGRNAFKQRLQELGVTMASEADINAAFLRFKELADRKSEIFDEDILALVSAEEHSNVDEQFAFVSLSQHSETGERPQAKVVFTVQGKEVTGESDGNGPVDASLKAIESHVKSGAEMVLYSVNAISGSTESQGEVTVRLQNAGRVVNGVGADPDIVVASAKAYLSALNKLQSQAEKVAAQG
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: HDA_CROS8
Sequence: MPLWLPDDETFASFWPGDNPSLLAALQTMLRHDRSGYIYFWSREGGGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLEGMEQLSLVCIDNIECIAGDEPWEMAIFNLYNRILESGNTRLLITGDRPPRQLNLKLPDLASRLDWGQIYRLQPLSDDDKLQALQLRARMRGFELPEDVGRFLLKRLDREMRTLFLTLDQLDRASISAQRKLTIPFVKDTLGL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: MINE_FRAT1
Sequence: MLAKLFGLSKKQQSASVAKERLQIIVAHQRSELHPRSSKISSHLLAELKDEIIEVVKKYVALSEENIRDIDLKVEDSSKNSTIEVNIPFN
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SBE22_YEAST
Sequence: MTSIQERGTSAHLHSLKEGEASDRSSEMLPKQRSIIGSHVQRPPSQTTLGRSRAGSNTMNKVSGLDIARRPSENLLSNMNCSDNGNGGNMLNSFVNSALPPPKVNPAQTRRERPASNSSIGTKTTEVFSSTSASSSLGDTSDEGEGSDADKSKINTFPSILMEKATQGRGADGNGMRSASNNTIVEATTDGSKMALQKSMSFDDTAAEKTMNKSRHSYQEQFSSKKSQSSLLNSKQRSRAKSQTCSSTGYNNSSILKTFGISSKISNSSDRIEASSLEFNVPSQKPLNCKPLTPSQKYRLRKEQSEMNLRNTIKRKEKFYDSQEQILELQEGDVDDSLIWNVPMASLSTNSFLASAKPDDMNNLAGKNDLSEYTGGLVNDNSEISYTKQNHRYSNISFASTTSNASLLDFNEMPTSPIPGLNKVTDFQFIQDTTKSLASVYLHSSNRLSRSKLSERTKSSDFLPIELKEAQNQGMEDLILVSENKLDVVSHSRPSWLPPKDRQEKKLHERQINKSMSVASLDQLGKNKDREEKLIRDETNRQKYVLLLDRDITRNSSLQSLSKMVWDTPFSDETRSTIYSEILQSKTRFITKNYIQPFHELQELLTKMGDFPKNKEIEISQLIETSLRRKVSGLHDICPDLMLLLKIKSISSQGIVTGDELLFHHFLVSESFQNLGLNEIWNIVNLVQMTCFNDLCKEKFDAKVLERKGVVAGYLSQNEEFKDEFNTECINSTTWWNILERIDHKLFMWIMDIIVVNNSQSYKNSPINEDEFVNKDWEYYRSKKVVINYKILISFALNVLLNYHFGFTDLRSLCNVNDQRFCIPVFINDEFVDADTVNAVFIKKWAHYYKKF
What is the function of this protein?
With SBE2, is involved in cell wall integrity and polarity processes like bud growth, through the transport of CHS3 and UTR2 to sites of growth.
What are the official names of this protein?
Protein SBE22.
What is the protein family that this protein belongs to?
Belongs to the SBE2 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: RT23_CAEEL
Sequence: MASFITRAERSGNIFSRVTGLIRAGQLNWADRPLWYDVYVSSPPLTPPDWNVKLAKYDEPIRSIFYEEDVLRAKFYKTYRSTAGIQVDSSRTSVSQQFINEYKLVKSENAEATDDQLFEMTQKRLNENGIVLK
What are the official names of this protein?
Probable 28S ribosomal protein S23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL10E_HYPBU
Sequence: MPQKPARCYTKRRSKAFSGPPYTRKEYIHGVPPPKIQKFVMGNPHGDYDYIVEVYVTERGQIRHNALEAARVAVHKYLSTTIGDQNYFFRVRVYPHHVLRENKMMAFAGADRLQEGMRQAFGKPVGTAARVYPGQAVLEVRVKKEHLDHAKEALRRGASKLPLPSRIRVIPLKEEAKAAA
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: U082_ARATH
Sequence: MASHCSMRVILLRFSNGVSSRSILNSTNHRLLSLTMTNTLSSLSSISPHTTTSHFTAASQQSDDQNCFRKLQLRKISISTPLCMGRRSSKIAGRKGAQDSKKAKLYCRIGKEVVSAVKKGGPNPVSNTTLATILDKAKELDVPKDIVERNIKRASEKGQEAFIEKIYEVYGYGGVSMVVEVLTDKINRSVAAIRSVVKDYGGKMADSGSVMFKFKRVRVVNIKVTEADKDQLLIIALDAGAEDVIEPPTYEDDTDEDREERYYKIVTSNENYSTILSKLRDEGVNFEPDNGSELLPLTTVEVDDEAMELNKELMQKLLELDDVDAVYIDQK
What are the official names of this protein?
Probable transcriptional regulatory protein At2g25830.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
Protein: CYB_MYOAS
Sequence: MANIRKSHPLLKIINHSLIDLPAPSNISTWWNFGSLLGICLGLQILTGLFLAMHYTSDTLTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLFLHVGRGIYYGSYNYLETWNIGIILLFALMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPTGLDSNADKIPFHPYYTIKDILGFIIMFLFLMILVLFMPDMLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILILMPLLHTSAQRSLMFRPIGQCLFWILVGDLFILTWIGGQPVEHPFIIIGQLASIMYFTIILILMPLAGILENKIMKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MFGM_EQUAS
Sequence: ASGPCFPNPCQNDGECHVIDDSHR
What is the function of this protein?
Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors.  Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner.  Zona pellucida-binding protein which may play a role in gamete interaction.  Contributes to phagocytic removal of apoptotic cells in many tissues.  Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing.  Promotes VEGF-dependent neovascularization.
What are the official names of this protein?
Lactadherin, MFGM, Milk fat globule-EGF factor 8, MFG-E8.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Peripheral membrane protein. Note=Located in the acrosomal region of zona-pellucida bound sperm.
Protein: YIHI_AERS4
Sequence: MSAKQPNRKPTGKRKESDASALDGRERKRAAKRKGLKAGSRQQAEQSSKNNNGKQAKDPRIGSRKPVALIVDEKGAKPVAPKPAKEKKLVMTPEQELAAIENDDRLNDLLDRLDAGETLEATEQAWVDQRVDRYQELMDELGIIDNDDDEEDDGSFDDASYEAPTQPASEEELWDRFTQVDYQPEPKPEPKKK
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: TCYP_ECOLI
Sequence: MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFGLALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSDLSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLAAIDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFAVHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGGATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILDSEDDAELAHH
What is the function of this protein?
Involved in L-cystine import (PubMed:25139244, PubMed:25837721, PubMed:26350134, PubMed:27481704).  Low affinity L-cystine transporter that is mainly involved in L-cystine uptake from outside as a nutrient (PubMed:25837721).  Is the primary transporter at high concentrations of cystine (PubMed:26350134).  Probably functions as a proton symporter (Probable).  Can also transport D-cystine, cysteine and homocystine as a methionine precursor (PubMed:25139244, PubMed:26350134).  Mediates accumulation of the toxic compounds L-selenaproline (SCA) and L-selenocystine (SeCys) (PubMed:25139244).  Can also transport S-sulfocysteine and is required for growth on S-sulfocysteine as a sulfur source (PubMed:27481704).  Plays the principal role in the 3-mercaptopyruvate sulfurtransferase (3MST)-mediated generation of endogenous hydrogen sulfide (H2S) (PubMed:28533366).
What are the official names of this protein?
L-cystine transporter TcyP, S-sulfocysteine transporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROC_CHLTA
Sequence: MHNQYGSIFSITTWGESHGPAIGVVIDGCPAGLSLSPEDFLPAMARRRPGQLHTSPRQEPDLVTILSGVYQNKTTGTPISLLIENKDVSSSSYEQLQHCYRPGHAQFAYEGKYGFADNRGGGRASARETASRVAAGVIAKKILLSQRIETLAFLSGFGTLESKNYPKLSDSLIQQVHTSPFYTLLPQEEIQNLLLLNPDDSFGGVVSFITSPLPIGLGEPVFGKLPALLAAAMMSIPAAKGFEIGAGFSSSQMTGSAYLDAFIADESGVSLQSNRCGGALGGISIGQPLEGRVAFKPTSSIKKPCSSVLKDGTPIAYRTPNQGRHDPCVAIRAVAVVEAMLDLTLVDLLLQHRCTQL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: AZOR_ECOL5
Sequence: MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFRYTEKGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAE
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: Y3376_SHESR
Sequence: MEKIFERLMYASRWIMAPIYLGLSLVLLGLGIKFFQEIFHILPIIFEMTEVDLVLVTLSLIDITLVGGLIVMVMFSGYENFVSQLDVGEDSEKLSWLGKLDSGSLKNKVAASIVAISSIHLLKIFMDVKNIDNDKIMWYLLIHITFVVSAFAMGYLDKMTRK
What are the official names of this protein?
UPF0114 protein Shewmr7_3376.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CINA_STRGC
Sequence: MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNESRLLSILEIAKGRSNLIILTGGLGPTEDDLTKQTLAKFLGRELSFDPDAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGILEVDGVTYVVLPGPPSELKPMVNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILSEMIDQQSDPTIAPYAKTGEVTLRLSTKALSQAEADAKFEAVEKEILSHKTFEDQSLSEIFYGYGDDNSLAQVAFDLLKSQGKTISAAESLTAGLFQATLADFAGASAIFSGGFVTYSMEEKSRMLDIPLGDLEEHGVVSAFTAGKMAEQARKLTESDLAVSLTGVAGPDSLEDHPAGTVFIGLASAAGTETIKVNIAGRSRRDVRKIAVLHAFNLVRSTLLNS
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: PPA22_ARATH
Sequence: MKLFGLFLSFTLLFLCPFISQADVPELSRQPPRPIVFVHNDRSKSDPQQVHISLAGKDHMRVTFITEDNKVESVVEYGKQPGKYDGKATGECTSYKYFFYKSGKIHHVKIGPLQANTTYYYRCGGNGPEFSFKTPPSTFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYADTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPLSEFRESSFGHGRLKVMDGKRAHWSWHRNNDSNSLLADEVWLDSLSTSSSCWPSSRSNDEL
What are the official names of this protein?
Purple acid phosphatase 22.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: SELA_MARSD
Sequence: MSNLFKYLPSVDSVLTRLEEEGVIDGLPRTLSRDLVNGFLDVCREEIKGGIITEEKQLSPDVLFPRLTCHVRAGAKPHFRRVLNGTGVVVHTNLGRSLLAESAVKAVTEACACYSNLEFDLKTGERGSRYSHVEKLICEITGAEAALVVNNNASAVLITLETLAKGREAIVSRGQLVEIGGSFRIPDVMTKSGAFLREVGATNRTHLHDYENAINEETALLMKVHTSNFRVIGFTKEVSGGELAELGRKHDLPVYEDLGSGNLTNFSGLGLMREPTVQEVVAEDVDVVSFSGDKVLGGPQAGIIVGKKKYIDAIKKNPLNRAVRIDKMTLAALEATLRLYLDPETAKREVPTVRMITEKPENLKKQAQALARTLRRELGETANIGVREGVSRVGGGAFPEQDLKTFLVTVVPSAKVTVEELKEGLLSTEPPLVGRIEEDAFCLDPRTLTREEYKLCAEAINQILE
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_METRJ
Sequence: MGSMSIWHWVIVAVIVMLLFGRGKVSDLMGDVAKGIKAFKKGMAEDETPPAVQAAPPPAEPVRTIPHATETSPGTAIPASHLPGGERKPV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YCCT_SALAR
Sequence: MKTGALTTFLALYLPVTVFATTLRLSNEVDLLVLDGKRVSGSLLRGADSIELENGPHQLVLRVEKNIRLSGNEERLYISPPLVISFDTQQTSQVNFHLPRLENEREASHFNAAPRLMLLDGDAMPIPVKLDILTTTSTAKVVDYEIETERYNKSAKRASLPQFATIMANDSTLLSDASELDAVPPQSQTLTEQRLKHWFRLADPQTRSHFLQWAEKQPSS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: IFNG_SAISC
Sequence: MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGDSDVADNGTLFLNILRTWREEGDRKIMQSQIISFYFKLFKNFKDNQSIQKSMETIKEDMNVKFFNSNKRKQDDFERLTNYSVTDLNVQRKAIHELIQVMAELSPAPKIGKRKRSQTLFRGRRASQ
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_RICTY
Sequence: MSILHVTILTVFPEMFPGTLGYSLAGQALHNNIWSYDIINIRDFGLTKHKNVDDKAYGGGDGLIMRPDVLGNVIEYALSLNHNTKIYYPSPRGSVFTQSFAKEMLKNKNIIFLCGRYEGIDERVIAEYNVKEISVGDYILSGGEIPTLTILDCLIRLLPGVLINQNTLSSESFEKDGEFQGGLECDLYTRPKIWHGRAVPSILLSGNRKLINNWRKEQSRMITKLRRPELLKDL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y493_MYCTO
Sequence: MGESTTQPAGGAAVDDETRSAALPRWRGAAGRLEVWYATLSDPLTRTGLWVHCETVAPTTGGPYAHGWVTWFPPDAPPGTERFGPQPAQPAAGPAWFDIAGVRMAPAELTGRTRSLAWELSWKDTAAPLWTFPRVAWERELLPGAQVVIAPTAVFAGSLAVGETTHRVDSWRGSVAHIYGHGNAKRWGWIHADLGDGDVLEVVTAVSHKPGLRRLAPLAFVRFRIDGKDWPASPLPSLRMRTTLGVRHWQLEGRIGGREALIRVDQPPERCVSLGYTDPDGAKAVCTNTEQADIHIELGGRHWSVLGTGHAEVGLRGTAAPAIKEGTPA
What are the official names of this protein?
Uncharacterized protein MT0513.
Protein: RS19_RHIL3
Sequence: MARSVWKGPFVDGYLLKKAEKVREGGRSEVIKIWSRRSTILPQFVGLTFGVYNGSKHIPVSVNEDMVGHKFGEFSPTRTYYGHGADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GP_BHAV
Sequence: MMFSRVMQLALICAVTCEDNPCLWERFTNSRDIEFMIPVVNLSTSRRLSMSQRICMVSMGKHWSRIFSEGEEDRGMKDLDPLLMSSLNWRGTAKTRSSNSFNFDILDGIFLGFLDLVKWGEEADRHTPIHPECIKSKVCGFMTASGPRIKTCTGKFRGADRHGHCTNRATPHEATNVISVGVQHAQEANQVDEHEARYISEARKSINPEICSIDGVEINQCDLASPGRWLMLHYASFRLQEGSLVYLSPGLNIKWSQINVPASDFYCINVSDHLNTHYRPCEVNCTDNCQGDELYCSVHQCARSAECKCSFIGSRGMAEVQIGDRWFKPAVVGSQQFFVKEDVPVLQQPSADCTTCSMTCTAEGIAISSIKDELKDVTVCVEGFCSTRVSKGSKVWKIEFHNQYPSSGSVALARGTTVSGETFELTAECGRRTGCEQINCLFCREMLSNPQCYPYGKWFLLFLILATLYIIVALLKTIMRIFMACLSVLYGPFIIIIKISRCLGRLGKRKGERTYVRLMEALDDERKPEVVRAPVSLGRTKQPRIVLFIVLALLVHMALCCDESRLVEETSVTCNPGPDNIFSCSTKEMITVKELRAGKTICVSLKGPGGSLSSPIKIKMLDIVGRSDLLDIYFTFNGHANCKSVRRCRWAGSCGNSGCLGVGKEDYDRELGDQESSLHPNWRDCYDGCGGAACGCFNAAPSCIFLKRYVTNADSRVFKVFKPSAWFLSTKIVVETTSHKEDVTLKSGEAKVIDKVSFHYRTDKNLFAGMSIPPIVTEVKREGKPLSFFLENQGQHPKCKDENSARTSSASNCIVDQNTISANVRVDDVSCRSNLVSISGMSTLKPLPQRVGDFLIQLHNDEPVLLATGDSGVVEGELQIDLSHKKISIKVDTTVCRGTVKELKGCVGCTKGAFASLEIHSTSAGSASLQCSLSSCYMEVQKGVNNVNCSLRFSKAVVEETCVLACSGSKEQLSIKGNLIIGGDFKKLTEDSATSFSHTDSKDTRIHLQTGLMNWLDTLFGASLLGKILGIGLAILSPFILILILRWILRVVLRRSRIRREPKYEMAKYS
What is the function of this protein?
Structural component of the virion that interacts with glycoprotein N (By similarity).  Acts as a class II fusion protein that is activated upon acidification and subsequent repositioning of the glycoprotein N (By similarity).  The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation (By similarity).  They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after endocytosis of the virion (By similarity).
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the phlebovirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Interaction between Glycoprotein N and Glycoprotein C is essential for proper targeting of Glycoprotein C to the Golgi complex, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=Interaction between Glycoprotein N and Glycoprotein C is essential for proper targeting of Glycoprotein C to the Golgi complex, where virion budding occurs.
Protein: GET3_PICST
Sequence: MDFELEPTLESIVQQDTLKWIFVGGKGGVGKTTTSSSIAVQLALNHPNDQFLLISTDPAHNLSDAFCQKFGKDARKVDGLSNLSCMEIDPEAAMSDLQQQAQQYNNDPNDPLKSMMNDMTGSIPGIDEALSFMEVLKHIKSQKVDENDDKDKISYRTIIFDTAPTGHTLRFLQLPSTLQKLLSKFQALSGKFGPMMSMLGGGNQQEMFDKLNEVQKNVTEVNEQFTNPDLTTFVCVCISEFLSLYETERMIQELMSYNMDVNSIVVNQLLFADDDEKPCKRCVSRWKMQKKYLDQMAELYEDYHLVKMPLLGTEIRGVENLKKFSKFLLTPYDPKVNGDLVTSLEEK
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting.  Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.  Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Golgi apparatus. Note=GET1 and GET2 are required for targeting GET3 to the endoplasmic reticulum.
Protein: D6KL1_ARATH
Sequence: MASKYGSGVLPENKKEKGDKETPETSYSSQSVSVNTLADQVSSTLSFAPSSDSKTGGEVKFNEKSDQSGKSNTCRPSTSSDISDESTCSSFSGNNKPHKANDVRWEAIQAVRTKHGVLGLNHFRLLKRLGCGDIGTVHLAELHGTRCFFAMKVMDKGALASRKKLLRAQTEREILQCLDHPFLPTLYSHFETEKFSCLVMEFCPGGDLHTLRQRQPGKRFSEQAAKFYVAEVLLAMEYLHMLGIIYRDLKPENVLVRDDGHVMLSDFDLSLRCTVSPTVVRSTVLASEGQKNSGYCAQPACIQQPSCISAPTTCFSPRYFSSKSKKDKKMKNETGNQVSPLPELVAEPTSARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVVGQPLRFPESPVVSFAARDLIRSLLVKEPQHRLAYKRGATEMKQHPFFEGVNWALVRCASPPEIPKPVDYESAPATPAAATSTSVKSDQSNYLEFDFF
What is the function of this protein?
Protein kinase that regulates the auxin transport activity of PIN auxin efflux facilitators by direct phosphorylation.  D6PK-mediated PIN phosphorylation promotes auxin transport in the hypocotyl and this is a prerequisite for PHOT1-dependent hypocotyl bending.
What are the official names of this protein?
Serine/threonine-protein kinase D6PKL1, Serine/threonine-protein kinase AGC1-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Colocalizes with PIN1 to the basal (lower) membrane of root cells.