PharMolix/UniProtQA huggingface dataset:
Protein: FLPA_METMZ
Sequence: MPEIRQLSEGIFEVTKDKKQLSTLNLDPGKVVYGEKLISVEGDEYRTWDPRRSKLGAMVLKKFDIPLKRNSKVLYLGAASGTTVSHVSDIVSEGAVYSVEFAPRSMRDFIGLASRRKNIFPILADAGKPDSYAHIVEPVDVIFQDVAQPNQAEIAARNAVRFLKKDGYLLLSIKARSIDTAASPKEIFKEEVK
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: SVOP_PONAB
Sequence: MEEDLFQLRQLPVVKFCRTGESARSEDDTASGEHEVQIEGVRVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCGISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQESSHREWGQEMVGRGMHGADVTRSNSGSQE
What are the official names of this protein?
Synaptic vesicle 2-related protein, SV2-related protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Protein: ILF2_MOUSE
Sequence: MRGDRGRGRGGRFGSRGGPGGGFRPFVPHIPFDFYLCEMAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE
What is the function of this protein?
Chromatin-interacting protein that forms a stable heterodimer with interleukin enhancer-binding factor 3/ILF3 and plays a role in several biological processes including transcription, innate immunity or cell growth (PubMed:10574923).  Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus.  Together with ILF3, forms an RNA-binding complex that is required for mitotic progression and cytokinesis by regulating the expression of a cluster of mitotic genes.  Mechanistically, competes with STAU1/STAU2-mediated mRNA decay.  Also plays a role in the inhibition of various viruses including Japanese encephalitis virus or enterovirus 71 (By similarity) (PubMed:10574923).
What are the official names of this protein?
Interleukin enhancer-binding factor 2, Nuclear factor of activated T-cells 45 kDa.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: BUD21_YEAST
Sequence: MSNGHVKFDADESQASASAVTDRQDDVLVISKKDKEVHSSSDEESDDDDAPQEEGLHSGKSEVESQITQREEAIRLEQSQLRSKRRKQNELYAKQKKSVNETEVTDEVIAELPEELLKNIDQKDEGSTQYSSSRHVTFDKLDESDENEEALAKAIKTKKRKTLKNLRKDSVKRGKFRVQLLSTTQDSKTLPPKKESSIIRSKDRWLNRKALNKG
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Has a role in bud site selection maybe via the regulation of expression of bipolar budding components.
What are the official names of this protein?
Bud site selection protein 21, U three protein 16, U3 small nucleolar RNA-associated protein 16, U3 snoRNA-associated protein 16.
What is the protein family that this protein belongs to?
Belongs to the UTP16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HSCA_SALPC
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLPDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTISSVKRMMGRSLADIQARYPHLPYRFKASVNGLPMIDTSAGLLNPVRVSADILKALAARASESLSGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAIAAKIALSDADTVRVNVAGWQGEITREQFNDLISALVKRTLLACRRALKDAGVEPQDVLEVVMVGGSTRVPLVRERVGEFFGRTPLTAIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPPLPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDGEIASMIKDSMSFAEQDVKARMLAEQKVEAARVLESLTGALTADAALLSAAERQCIDDAAAHLSAVAQGDDVDAIEQAIKNVDKQTQEFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YIDD_RICFE
Sequence: MTRILLLLLRFYQYFISPLLGNNCRFHPTCSEYAKEAITTHGTLKGLWLTFKRIIKCQPFCNGGYDAVPLSIKNSKLFNKKI
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HEM3_DECAR
Sequence: MSRPSKIVIASRESRLAMWQAVHVRDRLSSLNPGAEVVILGMTTKGDQILDRPLAEIGGKGLFIKELEVAMQEGKAHLAVHSMKDVPMVMPEGFVLAAISARENPRDAFVSNKYNGLDDLPAGAIVGTSSLRRESILRAKYPQLVIKSLRGNLDTRLKKLDAGEYDAIILAAAGLIRLGMENRIKSVLTAEQSLPAPGQGALGIELIDGAADMADVVAPLNDPETAHCVKAERAFSRALGGSCQVPLGGYAIIDNGQLWLRGFVATADGQEVVSAELRGNPADDEALGLQLAAELRAKGADAILEKLAHCK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: TR64B_HUMAN
Sequence: MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSEKPNFNTNLVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCRDSRTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT
What are the official names of this protein?
Putative tripartite motif-containing protein 64B.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: ACCD3_MYCTU
Sequence: MSRITTDQLRHAVLDRGSFVSWDSEPLAVPVADSYARELAAARAATGADESVQTGEGRVFGRRVAVVACEFDFLGGSIGVAAAERITAAVERATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAIQLHNQARLPYLVYLRHPTTGGVFASWGSLGHLTVAEPGALIGFLGPRVYELLYGDPFPSGVQTAENLRRHGIIDGVVALDRLRPMLDRALTVLIDAPEPLPAPQTPAPVPDVPTWDSVVASRRPDRPGVRQLLRHGATDRVLLSGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGSTVGPAALREARRGMALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHCLAELVTLDTPTVSILLGQGSGGPALAMLPADRVLAALHGWLAPLPPEGASAIVFRDTAHAAELAAAQGIRSADLLKSGIVDTIVPEYPDAADEPIEFALRLSNAIAAEVHALRKIPAPERLATRLQRYRRIGLPRD
What is the function of this protein?
Component of a biotin-dependent acyl-CoA carboxylase complex.  This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate.
What are the official names of this protein?
Probable biotin-dependent acyl-coenzyme A carboxylase beta3 subunit.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
Protein: TDRD5_AILME
Sequence: MSEQERVQECLRKEIRSLLISTKDGLTPQQLEKEYLLMVGSHLPLRILGYRSTMELVLDMPDVVTVCPYGDGTVILRAIPDESTKGIASLVAKQRSSHKVRNSAQKGRASVCSGPSSRRQVPYRGRLPPILPAVVKSELKDLLALSPILLSDFEKAFVRRFGRSFQYVQYGFFSMFEVLNAASDVISVEQTRAGSLLMLKKSVSEEKQRGWPAGGKMFTQPFRMKQQGSYSTGSPVAKARFSQPTSNMEPPKQILNVEKTFKSNVVETSRLNHTEKLNQLENTFKSVIAQIGPGGTISPELKHKIRFVVSKFPEGLLISKLLREFEIIFKEQLSPKKLGFLNVIELVGALSDILRVEFREGEQDLLVFDADMKPLPPAQSDKKIEVKAYVSSPPRNSLSTAAVKETTWDCPPKNRKEPEQKICKKPNLVVKPLQLQVEVNKSQRNLAMANHDIPPDAVRDKKLCRLPLLDTSTLVGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYTLPEYFIQPGHLCCVRISEDKWWYRVIIHRVLGKQEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENVPSKGFRELNPLALYTKSSSGPEDVVLTELGYPSQQHYFNEDREISPQSKESELSTLDEIPTGMPCLESVTIGDDVWDENWLPLQAKMGKGGDAASHLFTSSLGGKKPYPSCKEMPQKDWCFSGPKDVWDDSWQPSGLMNGVKVEVQKQEGLGAQEKNTGTTRIQKPPPVESSLDLSTLPKLEEFYSSLIQSQQSAEGSQPEPSCIQTPAKPVQLSTAALSASPMALDSAEKHSGSVESSPESLKNDFSSSHAITVFKDKSHGAMDQLSLILSPEHQISQKLYIPRSTATAALGAAARLATSRSLLHWYPSVKRMEA
What is the function of this protein?
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity.  Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Required for chromatoid body (CB) assembly (By similarity).
What are the official names of this protein?
Tudor domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the TDRD5 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.
Protein: YTM1_ASPFC
Sequence: MNDGSNSDATATSSAAQRQVRVQLTSKQEDIALPDNTGPILVPTSLRRYALSTLVNKLLGNDKPIPFEFLINGTFLRTSIDEYLTANGISAETTLEIEYVRALIPPLHIASFQHDDWVSSTDVLSATSPAATWASATISQGQEKILSGSYDGLLRVWNMSSQIVATSPAAADGGHTASIKAAKFVTPNQIASAGLDRTVRLWKYAESDEGFSGTIAPQLELYGHKSGINSLAVHALSNRILSASSDNSVGFWSTKKSDAPAAPDDLLPSAASRSSKRRKLNSSVTVPQRGPLALLSSHTAPVSAAIFDAKDSTVGYSASWDHSMRTWDLVTSALVDTRTTSHSLLSLEHLPELNLLAAGTSARHITLIDPRASATTISAMTLRGHTNAVVSLARDPHSTYGLISGSHDGTCRIWDIRATKTDKDGAVGESVYSISRKSLEEQGRSDTKRVGGEGVKVFSVCWDKTVGIVSAGEDKRIQINRGEGVLSA
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ytm1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: PURA_DESAH
Sequence: MPNIVVVGTQWGDEGKGKIVDLLSGYADYVVRFQGGNNAGHTMVVDGNEIISHLVPSGIIQNKVCFIGNGVVVDPLVLLEEIDYLDSRGIDVSPERIKISDRAHMIMPYHKSIDQARELKKGDAKIGTTGRGIGPCYEDKATRRGIRFADLLDEALFAEKVTTIMEEKNFYLKNYFKTDTLDPGAVIKEFMGLRDRLLPYISDVSVALNKGMDQGKQVLFEGAQGTHLDIEHGTYPFVTSSSTVAANAACGSGVGPGKLDHVMGIVKAYTTRVGSGPFPTELFDEIGDRLQKKGAEFGATTGRRRRCGWLDMVMLKNAARLNGLTGLVITKLDVLDGLEEIKICTGYEHKGKVYDAFPPAIKTLEECTPVYESHPGWTENISKIKDYEDFPENTKKYLDRIKELSGVDIKIVSVGPGREATIVLDNLFC
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_THISH
Sequence: MAVERTLSIIKPDAVAKNVIGEIYTRFEKAGLKIVAARMMHLSREQAEGFYAVHKERPFFKDLVDFMISGPVIVQALEGENAVALHRDIMGATNPKDAAPGTIRADFAESIDENAVHGSDSLENAGKEIAFFFKPEEICARTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLP2R_MOUSE
Sequence: MRRLWGPGTPFLALLLLVSIKQVTTGSLLEETVQKWAQYKETCLKDLLEKPSGVFCNGTFDKYVCWPHSFPGNVSVPCPSYLPWWNKESPGRAYRHCLAQGTWQKQENSTDTWQDESECSENHSFKQNVDHYHHTLLSTLQLMYTVGYSLSLISLFLALTLFLFLRKLHCTRNYIHMNLFASFILRALVVLVKDMVFYNSYSRRPDSESGWMSYLSEISASCRSVQVLLHYFVGTNHLWLLVEGLYLHALLEPTVLPERRLWPKYLVVGWAFPMLFVIPWIFVRASLENTGCWAVNENKKIWWIIRGPILLCVTVNFFIFLKILKLLISKFRAHQMCFRDYKYRLAKSTLLLILLMGVHEFLFTFFTDDQVQGFSRLIRLFIQLTLSSFHGFLVALQYGFASREVKAELRKTWGRFLLARHWGCRACVLGKNFRFLGKCSKKLSEGDGAETLQKLQSSGVSSHLTAGNLRDHGAQPHRGRGAWPRASSLSESSEGDFTLANTMEEILEESEI
What is the function of this protein?
This is a receptor for glucagon-like peptide 2.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
What are the official names of this protein?
Glucagon-like peptide 2 receptor, GLP-2 receptor, GLP-2-R, GLP-2R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDC_SHEB5
Sequence: MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAAVTATSKLITVKTDQLDVQINPIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAKSNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSAISDTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGMAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDRQKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKMQPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGLK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATM_RAT
Sequence: MLRVRCLRGGSRGAEAVHYIGSRLGGSLTGWVQRTFQSTQAATASSQNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPKDHLKKAVAEVEEMCNILSMEGVTVKRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYFD
What is the function of this protein?
Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.  Creatine plays a vital role in energy metabolism in muscle tissues.  May play a role in embryonic and central nervous system development.  Also capable of catalyzing the synthesis of a range of neuroactive guanidino compounds by utilizing alternative amidine donors and acceptors for the transamidination reaction.
What are the official names of this protein?
Glycine amidinotransferase, mitochondrial, L-arginine:glycine amidinotransferase, Transamidinase.
What is the protein family that this protein belongs to?
Belongs to the amidinotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: ATPB_ORITI
Sequence: MKLKAKYKQQSKVGKVVQVVSAVVDVSFAGKDLPHILNALECTINNEKIVLEVVQHIGDDIVRCLAMNSTDGLFRGAEVIDTGEQIKVPVGKSILGRILNVVGQPIDDLGPIKCDNFSQIHKDAPKFINQSTSRKILITGIKVIDLLTPYISGGKIGLFGGAGVGKTVLIMEIINNVAKAYKGYTVFTGVGERTREGGDLYKEMVGSNIIDLNKLENSKVTLVFGQMNEPPGARARVALTGLTIAESFRDMNEGEVLLFIDNIFRFTQAGAEISTLLGRIPSAVGYQPTLATDIGSLQERITSTKFGAITSIQAIYVPADDLTDPAPVACFAHLDATTVLSRKIAELGIYPAVDPLNSSSQILDANVIGQEHYSVATKVQEILQTYKSLQDVIAILGVDELSDDEKRIVSRARKIQRFLTQPFHVAEVFTGKQGRFVSLEDTIYGFKGLIEGKYDDLPEMAFYMVGSIDEAIEKSKTL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GSTA4_RAT
Sequence: MEVKPKLYYFQGRGRMESIRWLLATAGVEFEEEFLETREQYEKLQKDGCLLFGQVPLVEIDGMLLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIIGAPFKAPQEKEESLALAVKRAKNRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEEVSAPVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGHYVDVVRTVLKF
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase alpha-4, GST 8-8, GST A4-4, GST K, Glutathione S-transferase Yk, GST Yk.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_SYNS9
Sequence: MVSTSNGSDPLTIGGRLFSCRLLTGTGKYPSINSMQSSIERSACEMVTVAVRRVQTGAAGHTGLMEAIDWSRIWMLPNTAGCTNAEEAIRVARLGRELAKLAGQEDNNFIKLEVIPDSRHLLPDPIGTLQAAEALVKEGFTVLPYINADPLLAQRLEEVGCATVMPLGSPIGSGQGLNNAANIALIIENATVPVVVDAGIGVPSEAAQAMEMGADAVLVNSAIALAGDPPSMAEAMGKAVIAGRMAYSSGRLPRRGQASASSPTTGLISGKDK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_YERPY
Sequence: MKAQELREKSVEELNTELLNLLREQFNLRMQAASGQLQQTHLLKQVRRNVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DAPA_NITEC
Sequence: MFRGSHVAIVTPMLEDGALDLDRFCALIDFHIEQGTDGIVVVGTTGESPTVDFDEHDLLIRTAVSYADGRIPIIAGTGANSTREAIELTVFSKNAGADACLSVAPYYNKPTQEGLYQHFKAIAEAVDIPMILYNVPGRTVADISNETTLRLAQIPGIVGIKDATGNIARGCDLVQRVPDNFAVYSGDDATALALLLLGGHGIISVTANVAPRLMHEMCTAALSGDLAQARAINARLFKLHIDLFVEANPIPVKWAVAKMGLINENIRLPLTALSSQHHELIRKAMLQAGITV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_FLAJ1
Sequence: MGNILNQIGIENYIFLSVVLFCIGVFGVLYRRNSIIVFMSIEIMLNAVNLLFVAFSTYHQDAQGQVFVFFSMAVAAAEVAVGLAILVSIFRNIGSISIDNLKNLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSTA4_HUMAN
Sequence: MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4-hydroxynonenal (4-HNE).
What are the official names of this protein?
Glutathione S-transferase A4, GST class-alpha member 4, Glutathione S-transferase A4-4.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_ACTP2
Sequence: MFWFKNVMIYRLTSPLSLESHSLEDQLQQTKFTPCSQSDMSKFGWSSPLSGSELLHFSQSKQFLLVSHKEDKLLPANVIKKETEERIAVLEEKEARKLKKTEKQAIKDDVVAMLLPRAFSKHQFTAIWLDLDAQLVYVDAGSSKRAEDTLALLRKTLGSLPVVPISFALLPSEVMTNWIAKGHTPNWLNLLEEAELKSFDTDSVVRCKRQDLESEEIAQHLQASKFVTKLAIDWENHFSCVLNEDATLSRVKFADEVREKNDDILKEDIAQRFDADLLLMTEELKLFTQKMIEEFGGIKERI
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FLAE_VIBAN
Sequence: MAITVNTNVSALIAQRHLGSASEMLNQSLERLASGKRINSAKDDAAGLQISNRLESQMRGLDVAVRNANDGISIMQTAEGAMQETTSLLQRMRDLSLQSANGANSKADRQALQEEMGALNDELNRIAETTSFGGRKLLNGSFGQSSFQIGASSGEAVQVSLKNMRSDSLDMGGFSYVAAGMADSQWRVTQDNRQLTMSYTDAKGKQHNIQIQAKVGDDIEELATYINGQTDKVSASVNDKGQLQLFMAGKETSGTIDFKGSLANQLQMNVTGYEAVDTLDITEVGGAQRAVAVIDTAMQYVDSHRSELGALQNRFNHAINNLDNVHENLASSNSRIKDTDYAKETTQMVKQQILQQVSTSILAQAKKQPNLALALLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  FlaE is not essential for flagellar synthesis and motility.  May have a role in virulence unrelated to motility.
What are the official names of this protein?
Probable flagellin E.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: MEIS1_MOUSE
Sequence: MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDVTRSANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
What is the function of this protein?
Acts as a transcriptional regulator of PAX6.  Also acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2.  Required for hematopoiesis, megakaryocyte lineage development and vascular patterning.  May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.
What are the official names of this protein?
Homeobox protein Meis1, Myeloid ecotropic viral integration site 1.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.