PharMolix/UniProtQA huggingface dataset:
Protein: TOLB_AROAE
Sequence: MNILLSRFRLLLAAALAALSWGAQAQLSIEITGAGATRFPVAIPLFENEGSLPRGITDVVRADLERSGLFSLVDMGLVTLPATAVPDLAGVRARGADAVLAGSLYPQADGRYDVRFRLFDTQKQTELGGLSLRMTPAQNRATAHRIADFVYEKLTGQPGYFATRIAYVVKSGPRYELQIADADGMNAQTALASREPIISPAWAPDGQRLAYVSFEAKKPVVYVHTLATGQRHVVANFKGSNSAPTWAPDGQRLAVVLTKDGQSQLYVLNADGSGLRRMATSPGIDTEPAWSPDGEWIYFSSDRGGSAQIYRIPASGGSAQRVTFEGNYNVTPRLSPDGRSLAFITRNNGRFQVAVMDLATRQTTILTDSSRDESPSFAPNGRMILYATESGGRGVLAAVSSDGRVKQRLSVQAADVREPSWGPLTR
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS13_AERPE
Sequence: MAGETSFKYIVRIAGVDIDGDLKLPYGLASIKGIGYTTAMAVIRMLGLDPEKKVGFLTEEEIRRLDEVLRDITQLGLPKWLYNRRKDYETGKDLHLIGSELIFYARRDIEREMKIGSWRGIRHKYGLKVRGQRTRTTGRLGMTIGVRKKR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GLMM_NEIG1
Sequence: MAKKYFGTDGVRGEVGQFPITPDFVLKLGYAAGQVLVQHDTDQKPTVLIGKDTRISGYMLEAALVAGFTAAGVNVVQTGPLPTPGVAYLTRALRLSAGVMISASHNTYSDNGIKFFAEGGVKLSDEVELEIEAKIDEEMKTQPSARLGRARRISGADDRYIEFCKSTFPGHSDLRGLKLVIDTANGAGYGVAPKVFHELGAQVVSIGNEPNGYNINEKCGATHTKTLQAAVLQNEADYGIALDGDGDRLMMVDKNRQVYDGDSLIYVIAKARAREGINIGGVVGTVMTNMAMEIALKEQGVDFCRAKVGDRYVLEQLNQRGWLIGGEASGHILCMDKHNTGDGIISALQVLAALQILNQDLATVCADWQPYPQTMINVRIQKGQKWQEASKDVLAEVEKELEGKGRVVLRASGTEPVVRVMVEARQADWARDGAERIAAAIGGI
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HIS7_STRGG
Sequence: MSPRVGRVERTTKETSVLVEINLDGTGKVDVATGVGFYDHMLDQLGRHGLFDLTVKTEGDLHIDTHHTIEDTALALGAAFKQALGDKVGIYRFGNCTVPLDESLAQVTVDLSGRPYLVHTEPENMAPMIGTYDTTMTRHIFESFVAQAQIALHIHVPYGRNAHHIVECQFKALARALRYASEHDPRAAGILPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXA5_LAGLA
Sequence: MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAAGASAAPAEPRYSQPATSTHSPPPDPLPCSAVAPSPGGDSHHGGKNSLGNSSGASANAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Also binds to its own promoter.  Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' (By similarity).
What are the official names of this protein?
Homeobox protein Hox-A5.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GAG_HV1W2
Sequence: MGARASVLSGGELDKWEKIRLRPGGKKKYRLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEKKDTKEALDKIEEEQNKCKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQATQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNPTTIMMQKGNFRNQRKT
What is the function of this protein?
p6-gag: Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: FENR_DEIGD
Sequence: MQSKQAPDTEILVIGGGPAGLHAAFYAAWRGLSVRVLEARGEVGGQLLALYPDKVIYDVPGVPQVRAAELVAALCAQLGPLDVDLRTGEVARTLEPDGTGGWVIGTAGARHRARAVILAAGMGALLPREVRVPGADTHPDVRADLPDPAGFAGRRVLVVGGVPQATRAAVELLEAGATVTLTHRRAGFRGDPLTLARLETARQASQMRLLAPAVLSRLTPQGAELVVEGAPLAVRADTVLILNGYLPDLSPLQAWPLAWDGEYVPDGPSGQTVLPGVYVIGDLARSGGDFKLLSLAFAQAAVAANHAAHHVRPELKMRPGHSSERGGYPVR
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: CHS1_CRYNH
Sequence: MSSNQDVPLPFTSSRPLPSRQPTTSRPGGTLKRNKTLTRPERHVAPAPLVAPPTQSFSPTSPLPQSDGFLNIDWWRLWAYATTFWAPPVLLRWFGIKEKQSRQAWREKIALCWIAVLLGGVVGFVTMGLQRALCPADQQNQSMYQRLGDTNMTLSISGWAFNISTSITQSNVDFYSLANQMPGQDITDLFTRSVSDYPACTSSLAYSSGAFCNSTSSSSGTSCVLSSMSQETFDSLQIQNTSLLEGYSWDQVAKLENYMVIDGYVLNMSPYLSFNPTAVEGDEVDSIIRHVLSNQTGSGKDATRLFFNRQVPQDAVGCMKARYVAGRIDKITPGCFVASFFLYVSLVVILAVVLARFAMACVFNWFLSEKLVKPVTEKELGRKGINPTIMPEGANVSVNNKLGTAPWAGGGGAAEGKGGGVGPGKKLVNGKKINPLSPLPSPSHSLPNAPLITLSQIGPELFTVCLVTCYSEGPSSIRGTLESIASTNYSDRRKLIWVVCDGMITGQGEKRSTPDVCVGMLDADGRFGNPVPMGYEAVGSGQKRENRAMVYAGHYVSRNGHRTPTIIVVKCGMPQEATEKKPGNRGKRDSQLILMNFFSRVTYNDRMTPLDFDLFRKIWTLMGVTPDYFEAVLMVDADTRIYPDSLKHLVNCMHHDNMIMGVCGETRIANKRQSWVTAIQVFEYFISHHHVKAFESVFGGVTCLPGCFSMYRIKARKDGDNDWVPILVKPEIVNEYSQSEVETLHQKNLLLLGEDRFLSTIMLRTFPRRKNIFLPQARCRTVAPDTFSVLLSQRRRWINSTVHNLMELVRVRDLCGTFCFSMQFVVFMDLVGTVVLPVAICLTFALIVNSIITPPKSFEEAIPLMLLAIVLGLPAILILITTRKVVYVAWMLVYLLALPIWNFVLPVYSFWHFDDFSWGETRRVEGEIRSKGHDDSTAVFNGTTIPLRRWEDWEKSRLRKLRREEKRRKEMERQFGAGFHGDPRLGGDLRGMGMGERPWARSEYDSDNGSLYSSEEDMWGGEVGGYNEHNPAFPPPPIALPPTDDPVSNINGETLGMDEMAAILDSGFDDDPQSQSTYPPLSHPRPHAHPPPPPISRTLANAPSPVRRHQHEYNAPQPRFNRIDSPSFGSGPNSARSSPHSADAGRYAAGEYVSIDRQDTNDLDAQMPHSGGSVSSSVESRPHGVGHAKKRSGGGAGIGAGTGARGGGYGPLGPLADVNEVGRGQTRGYGGSGKDR
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1, Class-IV chitin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREE_PARXL
Sequence: MRTIDKLIAPHLKLAPVLVKRAPTLTLAFDDRRKSRLAATLDSGEEVALLLPRGTVLRDGDVLVADDGGLVRVIAAPEAVLYVRAKDALTLTRAAYHLGNRHTPVEVGADYLKLEFDPVLADMLKRIGATVDQVSMPFQPESGAYGGGHKHGHDETFAEDYALAQQVFGEHHGHEHSHDHEHGHSHAAHEHSHGHDHTHGHDHDHGDHVHDESCGHGHHHHHAHR
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_ECOLC
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: HEM3_SHEPA
Sequence: MSQNLIRIATRKSPLAMWQAEFVKAELEKIHEGLTVELLPMSTKGDIILDTPLAKVGGKGLFVKELEVAMLEGLADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNTYKTIEDLPQGAVVGTSSLRRQCQIRAARPDLVIKDLRGNVGTRLAKLDAGNYDAIILAAAGLKRLKLEERIASFISAEQSLPANGQGAVGIECRTDDARVKALLAPLEHAETRMRVTAERAMNTRLEGGCQVPIGAYAEIDGDTLSLRGLVGNPDGSQIITASSSGSTADAEKLGVALAEELLSKGAKTILDAVYANA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: SPIR2_MOUSE
Sequence: MARAGGGGAAAPERAGGAARPEPWELSLEEVLKVYEQPINEEQAWAVCFQGCRGLRGEPGGVRRIRDTADILLRRDGSVGARLEPEPTTMVVPPASSEAQMVQSLGFAIYRALDWGLDENEERELSPQLERLIDLMANSDCEDSSCGAADEGYVGPEEEEEAEGGPRAVRTFAQAMRLCALRLTDPHGAQAHYQAVCRALFVETLELRAFLARVREAKEMLKKLGEEEPREKPLAELDHLGHTDWARLWVQLMRELRHGVKLKKVQEKEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERQLRPVPQKQRTLHEKILEEIKQERRLRPVGAQHLGGRGFGSLPCILNACSGDIKSTSCINLSVTDTGSGSQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVALKRDRSFSEHDLAQLRSEMASGLQSAAQPPGGTEPPRARAGSMHSWRPSSRDQGFCPVSGQSQPLPSSALPSSLSSVDGPEAASPDTRHLWLEFSHPVESLALTVEEVVDVRRVLVKAEMERFLQDKELFSSLKRGKICCCCRAKFPLFSWPPTCLFCKRAVCTSCSVKMKMPSKKYGHIPVYTLGFESLQRVPTTKATPTLRRDAFQSLQGPKWRSVEEEFPHIYAHGCVLKDVCSDCTSFVADVVCSSRKSVDVLNATPRRSRQTQSLYIPNTRTLNFQ
What is the function of this protein?
Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:21620703, PubMed:21983562).  Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (PubMed:21983562).  Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis (PubMed:21620703).  Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (PubMed:21620703).  Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (By similarity).
What are the official names of this protein?
Protein spire homolog 2, Spir-2.
What is the protein family that this protein belongs to?
Belongs to the spire family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Detected at the cleavage furrow during asymmetric oocyte division and polar body extrusion.
Protein: URE3_PSYIN
Sequence: MDLLPREKDKLLIFTAALLAERRLNRGLKLNYPEAMAYISMEIIEGARDGKSVAEMMDYGRTLLTRDQVMDGIAELIPDVQVEATFVDGTKLVTVHNPII
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEXSF_BACTN
Sequence: MGLALCGAAAQAQEKPNFLIIQCDHLTQRVVGAYGQTQGCTLPIDEVASRGVIFSNAYVGCPLSQPSRAALWSGMMPHQTNVRSNSSEPVNTRLPENVPTLGSLFSESGYEAVHFGKTHDMGSLRGFKHKEPVAKPFTDPEFPVNNDSFLDVGTCEDAVAYLSNPPKEPFICIADFQNPHNICGFIGENAGVHTDRPISGPLPELPDNFDVEDWSNIPTPVQYICCSHRRMTQAAHWNEENYRHYIAAFQHYTKMVSKQVDSVLKALYSTPAGRNTIVVIMADHGDGMASHRMVTKHISFYDEMTNVPFIFAGPGIKQQKKPVDHLLTQPTLDLLPTLCDLAGIAVPAEKAGISLAPTLRGEKQKKSHPYVVSEWHSEYEYVTTPGRMVRGPRYKYTHYLEGNGEELYDMKKDPGERKNLAKDPKYSKILAEHRALLDDYITRSKDDYRSLKVDADPRCRNHTPGYPSHEGPGAREILKRK
What is the function of this protein?
Exosulfatase involved in the degradation of the glycosaminoglycans (GAGs) chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS).  2-O-sulfatase active on unsaturated non-reducing end hexuronate units.  Has a slight preference for HS-derived structures (PubMed:25002587).  GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B. thetaiotaomicron in the host gastrointestinal tract (PubMed:25002587).
What are the official names of this protein?
Delta 4,5-hexuronate-2-O-sulfatase.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
Protein: MTNN_BACC2
Sequence: MRIAVIGAMEEEVRILRDKLEQAETETVAGCEFTKGLLAGHEVILLKSGIGKVNAAMSTTILLEKYKPEKVINTGSAGGFHHSLNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADEALVALAEKCMQTEENIQVVKGMIATGDSFMSDPNRVAAIRDKFENLYAVEMEAAAVAQVCHQYEVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLEELK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: SYGA_STRPB
Sequence: MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGLPLLDEATRAILLAEDDE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRAM_I79A4
Sequence: MNPNQKIITIGSICMAIGIISLILQIGNIISIWVSHSIQTGSQNHTGICNQRIITYENSTWVNQTYVNISNTNVVAGKDTTSMTLAGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPIGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDDGAVAVLKYNGIITETIKSWRKQILRTQESECVCVNGSCFTIMTDGPSDGQASYRIFKIEKGKITKSIELDAPNSHYEECSCYPDNGTVMCVCRDNWHGSNRPWVSFNQNLDYQIGYICSGVFGDNPRPKDGKGSCDPVNVDGADGVKGFSYRYGNGVWIGRTKSNSSRKGFEMIWDPNGWTDTDSNFLVKQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPREKTTIWTSGSSISFCGVNSDTVNWSWPDGAELPFTIDK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: DRGX_MOUSE
Sequence: MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQTRSKKEALEAQQSLGRTVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPGPASKQAPPEGSQDKTSPTKEQSEGEKSV
What is the function of this protein?
Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain.
What are the official names of this protein?
Dorsal root ganglia homeobox protein, Dorsal root ganglion 11, Homeobox protein DRG11, Paired-related homeobox protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DUSC_VIBPA
Sequence: MRVVLGPMEGVLDHLMRQILTEINDYDLCVTEFVRVIDQVLPDHVFHRLCPELMQGSQTTSGVPVHVQLLGQEPHWMAENAIRAAELGARGIDLNFGCPAKMVNKSKGGAALLQHPELIHSVVKACRDAVPANIPVSAKIRLGWENPEDCFEIVDAIQSAGANELTVHARTKQGGYKASEIKWEYINKIRERFSIPLIANGEIWNFEDGQRCIETTGVDSLMVCRGAFNIPNLGNMVKHNHTPMVWSDVVDLLIYYSKFEMKGDKGLYYPNRVKQWFAYLRQSYPEANELFREIRTFNKAAPIVEHIQRYRDELQSRQSQVA
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: ANM5_ORYSI
Sequence: MPLGQRAGDKSESRYCGVEVLDFPAGEELPAVLSHSLSSSFDFLLAPLVDPDYRPTPGSVLPVAASDLVLGPAQWSSHIVGKINEWIDLDAEDEQLRLDSEITLKQEIAWASHLSLQACVLPPPKRSSCANYARVVNHILQGLTNLQLWLRIPLEKSEPMDEDHDGAKDNSDMSDTVDSWEWWNSFRLLCEHSSQLCVALDVLSTLPSMNSLGRWFGEPVRAAILQTNAFLTNARGYPCLSKRHQKLLTGFFNHSVQVIISGRSNHNVSQGGVLSGDENHTEDTAVRHALSPYLDYIAYIYQRMDPLPEQERFEINYRDFLQSPLQPLMDNLEAQTYETFEKDTVKYTQYQRAIAKALVDRVSDDDVSTTKTVLMVVGAGRGPLVRASLQAAEETGRKLKVYAVEKNPNAVITLHSLIKLEGWESLVTIISSDMRCWEAPEKADILVSELLGSFGDNELSPECLDGAQRFLKPDGISIPSSYTSFIEPITASKLHNDIKAHKDIAHFETAYVVKLHRIARLAPTQSVFTFDHPNPSPNASNQRYTKLKFEIPQETGSCLVHGFAGYFDAVLYKDVHLGIEPNTATPNMFSWFPIFFPLRKPIYVPSKTPIEVHFWRCCGATKVWYEWAVTAPSPSPIHNSNGRSYWVGL
What is the function of this protein?
Methylates arginine residues in proteins such as histone H4.
What are the official names of this protein?
Protein arginine N-methyltransferase 5, Shk1 kinase-binding protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_MYCPN
Sequence: MELNQLKSVPKARNHKTKTLGRGHGSGLGKTSGRGQKGQKARKSGLTRPGFEGGQTPLYRRLPKFGNARKGFLKQEWVVLNLNKIAKLKLDKINRASLIEKQVISAKSQLPIKLIGHTKLEKPLHFEVHKVSKQALKAVENANGSVKLLEK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SCPDL_MOUSE
Sequence: MATEQRPFHLVVFGASGFTGQFVTEEVAREQIASEQSSRLPWAVAGRSKEKLQQVLEKAAQKLGRPSLSSEVGVIICDISNPASLDEMAKQAKLVLNCVGPYRFYGEPVVKACIENGTSCIDICGEPQFLELMHAKYHEKAAEKGVYIIGSSGFDSIPADLGVLYTRNQMNGTLTAVESFLTINTGPEGLCIHDGTWKSAIYGFGDKGSLRKLRSVSCLKPVPIVGTKLKRRWPVSYCRELNSYSIPFLGSDISVVKRTQRYLHENLEDSPVQYAAYVTVGGITSVIKLMFAGLFFLFFVKFSIGRQLLIKFPWLFSFGYFSKQGPTQKQMDETSFTMTFFGQGYSHGTCVEKNKPNIRICTQVKGPEAGYVATPIAMVQAAMTFLSDASDLPKGGGVFTPGAAFSRTKLIDRLNKHGIEFSVISSSEV
What are the official names of this protein?
Saccharopine dehydrogenase-like oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the saccharopine dehydrogenase family.
Protein: QUEC_ECO5E
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKVLNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: DR2_HHV6U
Sequence: MIYCVLSTTPGTFWFPSGFDPKPYHPSADSKLLPLGLITLSACSTRVSATTRWSSFHATDPSLSWLTGSSPWLVILQGQGGSLFCHDVLQGRLYILSHSVSLFLKTGLRHCEAIYRAPLWRDRPLPSLWTCRDPDKAFLPTLLARSARRGLAAFYALWRLHLGSRSELSHPVLEWESTELVLTDWRRGRNEAQRDAPSVAEHFARCRPLLDELCGEGGWLPFAFLSTSPHVWLILTEGGPVLAVDVNDTSVWRIADDLELLRRLGSLLLLSGLRLPLRPPSGSGEAAGEPGYEEEERRGRASTASATAATSTRGPTRPTRVTRKGRVATGGVHLSARPESEEQTDGHHGRQESSDDHQRGGSGRGHRDDGAHRHANDKTEPQQRGEHEERKQTDSGRHEHAQESQVARRDEEETEQGDSERSCGGATQTYGGRGRHDSCPSIPLSVPGPDPRLWVPPPHLLFPSPLPPMTPVDDEPSVRPRCPPGPAEEPPTCRPRPPRPSSDTPLSAVSRPSAPPVPPPSTARVRFFLSSSSSSPSYSPAPLSPPSPVSPSSPRSPFIPPIRSPGLRAKPRVSSGHPAAFPPAPSSAPARSERVTSVPSSASPSASCVGKSQPPAAHTA
What are the official names of this protein?
Uncharacterized protein DR2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: MGT_STAAS
Sequence: MKRSDRYSNSNEHFEHMKHEPHYNTYYQPVGKPPKKKKSKRILLKILLTILIIIALFIGIMYFLSTRDNVDELRKIENKSSFVSADNMPEYVKGAFISMEDERFYNHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNDRSFTRKVKELFVAHRVEKQYNKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNKNSTTMSHITVLQSAILASKVNAPSVYNINNMSENFTQRVSTNLEKMKQQNYINETQYQQAMSQLNR
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate.
What are the official names of this protein?
Monofunctional glycosyltransferase, MGT, Peptidoglycan TGase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TPC_DICDI
Sequence: MIITTSNDEDKKTNVFVELAAGSFSGALTRFIVAPLDVVKIRLQLQRTQLNNNSNNNNKIIGKENVNYRGIINTMSKVIREEGIRSLWKGNFSAELLWVTYAAIQFSTYNEIIGILDPEYRKHQQRTDKDKPNYKPSSSITMIGGASAGILSTIVSYPFDIIRTNIVNNHNKTNFKQTFKTIIARNGGYSNLFSGINSSLFQIVPQMGFQFTFYETFKFISNKYTSSVNNNNNNPLNQFTCGLLSGAISKFLVLPFDVVKKRLQVNEKVGYGMKSCFRDLYFNEGGVKAFFKGGTPGIVKAGLAAALSFTFFEQSKRILLNKQ
What is the function of this protein?
Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria.  It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient.
What are the official names of this protein?
Probable mitochondrial thiamine pyrophosphate carrier, Mitochondrial substrate carrier family protein K, Solute carrier family 25 member 19 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.