PharMolix/UniProtQA huggingface dataset:
Protein: LDHD_DANRE
Sequence: MTLFRHLVRITSPRLPFICGSSRRFSAKTAAVERVVSSFRSVTGDEGVSVGSAVREQHGRDESVHRCRPPDVVVFPRSVEEVSALAKICHHYRLPIIPFGTGTGLEGGVGALQGGVCFSLRKMEQVVDLHQEDFDVTVEPGVTRKSLNSYLRDTGLWFPVDPGADASLCGMAATSASGTNAVRYGTMRENVLNLEVVLADGTILHTAGKGRRPRKTAAGYNLTNLFVGSEGTLGIITKATLRLYGVPESMVSAVCSFPSVQSAVDSTVQILQAGVPIARIEFLDDVMINACNRFNNLSYAVTPTLFLEFHGSSKSMEEQVSVTEEITRDNGGSDFAWAEDEETRSRLWKARHDAWYAAMALRPGCKAYSTDVCVPISRLPQIIVETKADLISNNITGPIAGHVGDGNFHCLIVLDPNDTDEVQRVHSFTERLARRALAMDGTCTGEHGIGLGKRALLREEVGPLAIEVMKGLKASLDPRNLMNPGKVLELTQTNTEQ
What is the function of this protein?
Involved in D-lactate, but not L-lactate catabolic process.
What are the official names of this protein?
Probable D-lactate dehydrogenase, mitochondrial, DLD, Lactate dehydrogenase D.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARSD1_ECOLX
Sequence: MKTLMVFDPAMCCSTGVCGTDVDQALVDFSTDVQWLKQCGVQIERFNLAQQPMSFVQNEKVKAFIEASGAEGLPLLLLDGETVMAGRYPKRAELARWFGIPLDKVGLAPSGCCGGNTSCC
What is the function of this protein?
Inducer-independent trans-acting repressor of the ars operon.
What are the official names of this protein?
Arsenical resistance operon trans-acting repressor ArsD.
Protein: ZCPW1_MOUSE
Sequence: MMAALQTHKEYEKGTKKTFAPPTQKLHSEKPQPSSWKEDAPGTSSPEAETKPSLLKASLKKEQKPTTEHGPNRGQERKLKAQDQPAKKKGKERTLTSAEFEEIFQIVLQKSLQECLETSSCVQHIRPTKLDEEPGIVPPATDKKDADPEKVITPDTPKIASSLEEEVNSEMGTSKLGQPVTEPSKKKFNRLSLSKQKKKAEDEKMEKIQDGRECSLKEKQKIVIQDQSQIRGPQKEEESGFGHCVIWVQCSSPKCEKWRQLRGNIDPSVLPDDWSCDQNPDPNYNRCDIPEESWAGCESDVAYASYVPGSIIWAKQYGYPWWPGMIEADPDLGEYFLFASHLDSLPSKYHVTFFGETVSRAWIPVRMLKNFQELSLELVKKCKNKNSNQKLEAAIAMAHRAEQTSIQERVNLFGFWSRYNGADISEEGEDLTLCESNNPESCLEKEEKDLEEEKEEEEEKKDPTLPRPKPAKMQTKKPKSRGPAGGPDGTPKKKTAKKSLVSESTVPPVPTLGGKEEQGNSDLDHPVPKKKFKAPENKTSATNLSEEKEIKIVSKCPTPSAQHGACPLGKEGLVPHMPPTQEAASFPPDDDCSSDLDLEQLMEDIGEPEERGEMQQRGSSEEFLAALFEE
What is the function of this protein?
Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3) that facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs) (PubMed:32374261, PubMed:32352380, PubMed:32744506).  Essential for male fertility and spermatogenesis (PubMed:31453335, PubMed:32374261, PubMed:32352380, PubMed:32744506).  Required for meiosis prophase I progression in male but not in female germ cells (PubMed:31453335).
What are the official names of this protein?
Zinc finger CW-type PWWP domain protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: IDH3A_BOVIN
Sequence: MAGPAWISKVSRLLGAFHNQKQVTRGFAGGVKTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVAAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYHDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEAASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIETACFATIKDGKSLTKDLGGNSKCSDFTEEICRRVKDLD
What is the function of this protein?
Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase subunits 3/4, Isocitric dehydrogenase subunit alpha, NAD(+)-specific ICDH subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PLSY_MESM1
Sequence: MSLEVIFGSNILLILVAYFIGSINFSIIVSKIFKKSDIREKGSKNAGATNMARNFGFKIGFLVFFLDVSKSFWFAIISAILRDFVPFFGAVITQLVVLFVIIGHVFPIYFKFKGGKGAATNLGMIASLNIILAIIGGIIFFAMIFRWKIVSLGSFITPFILVIFMIIPWMNSSIIAYVGYSDFYQPVRESFQGAWYLSSLFLFLAALIILFTHIPNIKKLIKKEESVLKFSKKSKKLA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
Protein: WNT9A_MOUSE
Sequence: MLDGSLLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLETEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQYQFRFERWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVKEFLGRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETSLKVGSTTNEATGEAGAISPPRGRASGSGGGDPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTCKG
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors (Probable).  Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity).  Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturation and for normal bone mineralization during embryonic bone development (PubMed:16818445).  Plays a redundant role in maintaining joint integrity (PubMed:16818445).
What are the official names of this protein?
Protein Wnt-9a, Protein Wnt-14.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: RNFD_VIBVU
Sequence: MSFFIASSPHAHSRKSTPDLMKWVALCALPGLLAQTYFFGWGTLVQLILAITIALSLEALVMLFRKRPPMRALRDHSALVTAWLLAVAIPPMAPWWIITIGLLFAIVIAKHLYGGLGQNPFNPAMIAYVVLLISFPVQMTSWSAPLPLIEAGHEVAKDPVTFGDLLSLIFTGLTIDGSSLQQVRAGIDGITTATPLDAFKTGLHSGATSSEILSQPIFEGFAGVGWQWVNLAYLAGGLILLKQRVIQWHIPVGFLGALLVMSSFFSLFFPGETASPLFHLLSGATMLGAFFIATDPVSASTTIKGRILFGAIIGTLVFIIRSWGGFPDGVAFAVLLANMCVPLIDYYTKPRTYGH
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COX23_CRYNJ
Sequence: MATQVPPSTTPTPFANRPAPPTKDLEIPEDYKKTFRGRGTVSKFVDPCEAARKASLDCLERTQYNRSECTDFFTAYKECKGNWLAQRKEDRMKGRDTV
What is the function of this protein?
Required for the assembly of cytochrome c oxidase.
What are the official names of this protein?
Cytochrome c oxidase-assembly factor COX23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX23 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: ULAB_ECOL6
Sequence: MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKAHFPQDVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIB component, Ascorbate-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXE_SHIB3
Sequence: MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDGADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRTEAAAERALPNGETGNV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rsx electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYQ_ECO27
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOF1_DEBHA
Sequence: MSRSGSEEERFSSDEGMEELGDFIVSDEEPNHESARDDDAEVHNDRLLQMTSTLKPNESQTQKLLRAHISVLVSALGGPDHTSPISPPPYKLGQDALACLKDIKRWIKSVDEKKGNFDVALACADSGLVVNDLLVILCQWDSQQNSKKPLKNARTMEKIMLSCLELLVLLTWPTDLNSESSENQKLHFASVRKSQIVYKKHILAYNKGQTLKAVIRLVLPTIAKHRIDREPRDNAILRLVLFFIRNVLNIEPANSSISTKSRKHVTNLDNLPTNVNYDDISMNAVLSCFKNNKVLMFLLTLSGSLGTDFDKETFGQPCLECIYLIIKGVKTQDILNPQQNSKQQQRYQQQQREQSQQDQNPIQSVTTTSGLELQDLLSEESKRKKFQTQNISTRHGRFGSLLSIQGNNTSYVISGQEALLDTNSSLAKLDESKKWNNRSHFKYDSDDYVKATSEFLNGSSVIILKEFIEQFLSGGCFNTLIECIGWLLSGTNDLNYVDDYEKACYFLTVAWFLNYKRERNVLFDILGTANLDEDDDGLDYGSVSAGLSEVNFILIISYFRESFEAKNWNSLHVAMICFKELLLISYSIFSRFSDRGLQGEEEADDDQEEIDKELAEGIIRKLFSFNDFLNIVIQIPQTASKHSPEYLSVCISVVHIILKSFESFANENIKLYIQTKRKRTKQNKKSINTLDKATEESLRDVIEGSDDELENERVKEVSRERRLDFKVTEVRFFQTSIVSTYVEYLSRYEELTHEEIKRCLSYFHRLFVIRKDFTGLYRMDFMYILQKLRSYLPKGSSTRDHVDEFIYYFMKKFKNAFERFPNPVEILFPRFEDMEYKIFLATGDLYLKPEKNNKRSSVKIAKNIEFIRDNFSLDEKLKILVTVLYIQEKESLVTWVIQELTKITTNRLMNLSSEQIESNTNEAVQLYPLEQHRRLLINNPYIRLLLTLVGFKVPFILEEPCELPDNVETSNLTECLDSIKMWSNKQPVTFDDGKDAMFFLRTKEGYNYEQDDDYDGHYDENDESIAFETGANPDGERHNLNELDELDKLEAALEGKSNKDTDLPRGVARIKNKKPKKDLPKKSKANSRKKHLSRRPPKSFKVVSDGEEEKQEKTKSAEFVHGSDDESDYEKENEFFDREERLRRLLEESGGIVNPKQLAEFKVSWSKLESSNGTDTAISVSKAIENTSFVEDTMPHTQNIPEELTLGAINESNSDIDTSSDSEPELNGSGAESVSAIENDKTSVSSFTPDIHNETSSKKRHIILQDRDSEDEVDITTGNHEIKASNPRKRRVVISDDEE
What is the function of this protein?
Involved in chromosome segregation during meiosis and DNA damage repair.
What are the official names of this protein?
Topoisomerase 1-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the timeless family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CRR2_XENRU
Sequence: GFGSLLGKALKIGTNLL
What are the official names of this protein?
Caerulein precursor fragment-related peptide R2, CPF-RP-R2.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL14_AZOC5
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRKYAHVGDIIVVSVKEAIPRGRVKKGDVMKAVVVRTAKDIRRVDGSVIRFDRNAAVLINNNKEPVGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MTMRC_DANRE
Sequence: MLSLGSGGAKSSKPSFVSYVTPEEIKLEKDPQKKEKHPDLLPGEVVFCSANPILKYTQDDLSQRGVFGTLLCTNFRVAFISDDAPQEEMSKTFKNKLYGENDIPLMCVDHIYGVYDEKRKLITGGLVKNKCPSKMIIHCKDLRVFQFCLTFSKEEDAKRIFQGIAHHCLEEKSLKCVFAFSYLRSTNPEMLRKREAIMFDSPEDWTQEMKRTKAQCRLVTENENFELSQRLPQYFVIPSALGDLFNYQGKGLPIWCWSHHSGCALFKASFPSMTQEDGDFQSHLDTMITAVARNYLYSVKTEDLSESLPTLQDIQQSYNKFKQYFLIDNTTDFWLSDVKWFSSLESSGWLDIIRQCLQKAVEVVECLEKDNTNVLITEEEGTDLCCVISSLAQIMLDPYYRTLMGFQSLVQKEWVAGCHAFLDRCNHLHQKDKECHSPVFLLFLECVWQLVQQHSPAFQFSETYLTVLSDSVHVPIFSTFLFNSAHHRESVMKAESPIAQSRPLSCPTVWDWSVQFDSKAQNFFFNPLYSEKVKHERTVRRPHKHKHQRQLSLPSSAFKTPTKKGFFKDETDSLKKMLRVKRISRWMGSPDSPVVASREFYESWQQRPLDYHGLLLPSLDGPSVRIWMQRYLRWIPEVHIMGGGSVAIMTKLMELLSQVEDLKRVLEQRDPSLATQPDHPPPLHHRLPSFGSSGRLSSSFPFTYSRNRSFKPIIPTGLMQSLMVADNLANQEDETS
What is the function of this protein?
Acts as an adapter for the myotubularin phosphatase mtm1 to regulate mtm1 protein stability and possibly its intracellular location (PubMed:23818870).  By stabilizing mtm1 protein levels, required for skeletal muscle maintenance but not for myogenesis (PubMed:23818870).  In skeletal muscle cells, does not regulate mtm1 subcellular localization (PubMed:23818870).
What are the official names of this protein?
Myotubularin-related protein 12, Inactive phosphatidylinositol 3-phosphatase 12.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Sarcoplasmic reticulum. Cytoplasm, myofibril, sarcomere.
Protein: RL2_PROMT
Sequence: MAIRSFKPYTPGTRSRVVTDFSEVTSSKPERSLVVSKHRKKGRNNRGVITCRHRGGGHKRLYRIVDFRRNKHGVSAKVAAIHYDPHRNARLALLFYSDGEKRYILAPADITVGQEVISGPDAPIETGNALPLSSMPLGSSVHCVELYPGRGGQMVRTAGASAQVMAKEGDYVALKLPSTEVRLVRKECYATLGEVGNSEIRNTSLGKAGRRRWLGRRPQVRGSVMNPCDHPHGGGEGKAPVGRAGPVTPWGKAALGLKTRKKNKPSNKYVLRKRRKVSKRSRGGRDS
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MLCE_PENCI
Sequence: MSEPLPPKEGEPRPQKEESQNDTLEATESKSQHITGLKLGLVVASVTFVAFLMLLDMSIIVTAIPHITSEFHSLNDVGWYGSAYLLANCALQPLAGKLYTLLGLKYTFFAFLCIFELGSVLCGAARSSTMLIVGRAVAGMGGSGLVNGALTILSTAAPKHKQPVLIGVMMGLSQIAIVCGPLLGGAFTQHATWRWCFYINLPIGAVAAFLLLVITIPDRISSTDSELSTDKPMANIKSTLRKLDLVGFVVFAAFATMISLALEWGGSTYTWRSSVIIGLFCGGGFALIAFVLWERHVGDAVAMIPGSVAGKRQVWCSCLFMGFFSGSLLVFSYYLPIYFQAVKDVSPTLSGVYMLPGILGQVIMAMVSGFAIGKTGYYLPWALGSAVLVAIGAGLVSTFQPHTSTVKWVMYQFIAGFGRGCGMQTPIIAIQSTLSPEQGALGISLAVFGQTFGGSLFLDFANLVFGSGLRTGLSKYAPTVDTQAVTAAGATGFRDVVSKNNLPGVVKAYSLAVDHTFYLAVGATACTFVFAFGMGWRKIATKNDTRAVPETDA
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of compactin, also known as mevastatin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase (PubMed:12172803, PubMed:12242508).
What are the official names of this protein?
Efflux pump mlcE, Compactin biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CKLF_HUMAN
Sequence: MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
What is the function of this protein?
Has chemotactic response in monocytes, neutrophils and lymphocytes (PubMed:11415443).  Binds CCR4 (PubMed:16137713).
What are the official names of this protein?
Chemokine-like factor, C32.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Membrane; Multi-pass membrane protein.
Protein: ERA_DESDA
Sequence: MTDLHYRCGWVALMGPPNAGKSTLLNALLGQKVTIVTPKPQTTRNQIVGILTDDDAQTIFMDTPGLTQVRGRLSKTMIQAVWQSLNQADIIMPVLDAHLYIRHPEFLDRDLAPVAQALASEERPMIVVVNKVDLFGDKSRMLPLLTRLHEMWPRADIFPISALHKDGLADLVELIRKKLPKGQAQFPEDQISTAPLRFMTAEIVREKLFMHLRQEVPYSVAVDVESWEEDEERGQTVIHATIYVARPMHKAMVIGRAGQSIKAIGTEARKDIQELVGGKVHLELWVKVREHWTEDTAFLRDLGLMAE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: PSBN_OEDCA
Sequence: MESPAFFFTLFLWFFLLSITIYSIYIGFGPPSKRLRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HEM1_PRIMG
Sequence: MHIIAVGLNFRTAPVEIREKLSFNEQELASAMKTLSGQKSILENIIVSTCNRTEIYAVVDQLHTGRYYVKAFLAEWFGIDKEEFSPYLTIYENDGAIEHLYRVACGLDSMVIGETQILGQVRSSFLLAQEEETIGTVFNQLFKQAVTLAKKAHHETEIGANAVSVSYAAVELAKKIFGDLSSKHVLILGAGKMGQLAVQNLYGSGAKKVTVVNRTFEKAQELANRFSGEAKPFADLQHALSEADILISSTGANDYVVTKQMMSEAERTRKGRPLFMVDIAVPRDLDPELDELETVFLYDIDDLNGIVESNLQERQKAADEIEIMLEAEIVAFKSWLGTLGVVPVISALRQKALTIQAETMKSIDRKLPDLSERERKVLNKHTKSIINQLLRDPIPHAKELAGEKHAEESLELFMKIFNIEQEVALQKEKEEQLHTSITSHSVAYQS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CCS1_ASHGO
Sequence: MIDPSESFEATYAVPMHCGDCTGEISRALRAVPGVQEVTPDLERQLVAVRGIAPPSSIVQALAATGRDAILRGSGEPDSAAVAILESASAGGPPVRGLVRAVQVAPNKTLFDITLNGLPGPAQYYASIRASGDVSRGAASTGPAWHVFEDAVACERASPLGADLCAGSALFVAPLAVQALIGRGFLVGADRGHALAGAAAVGVLARSAGAWQNDKVVCACSGDTLWQERGSARSANIA
What is the function of this protein?
Copper chaperone for superoxide dismutase 1 (SOD1).  Binds copper ions and delivers them specifically to SOD1 (By similarity).
What are the official names of this protein?
Superoxide dismutase 1 copper chaperone.
What is the protein family that this protein belongs to?
Belongs to the CCS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORC6_ARATH
Sequence: MDISDIGRKLSLDNNKLLIRKAAEIRRLCDAQFDSSIIGVGEICKAVICLEIAATRLQIIFDRQAAVKLSGMSEKAYSRSFNSLQNVIGIKIKLNVRELAVQFGCVRVIKSVQNVLSSYKERFLASLPASRRANADFTRPVFTAAAFYLCAKKQKLKVDKLRLIEVCGTSESEFSCVSTSMTDLCFDCVGISKEKKDAKDVKGNRDLLDVLPGKRRLEDGGYSSGDESSCYKRHKKMEEAKYEDWKSTVVNSIKKNPEKGTKRVIQASLNFPKKSETKELQVDS
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
What are the official names of this protein?
Origin of replication complex subunit 6, AtORC6.
What is the protein family that this protein belongs to?
Belongs to the ORC6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COXX_RUEST
Sequence: MTDASINASMTREEEASLGDYFALLKPRVMSLVVFTAFVGLMAAPIGVHPVIGFCAILFIAIGGGASGALNMWWDADIDQVMKRTKGRPIPAGKVDKGEALSLGLALSGLSVIMLALATNVFAGAFLAFTIFFYVVIYTMWLKRATPQNIVIGGAAGAFPPVIGWIAATGSMSVEPWLMFALTFLWTPPHFWALALFMRNDYDMADVPMLTVTHGRRSTRKHILVYTVILAAFALTTAFTSVGGPIYLTTAVVLNALFLKGAVQIWRRDEEICESDNFKIERSFFKLSLLYLFLHFGAILAEALLKPYGLGGW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL6_STRPB
Sequence: MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIKVEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTKLVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGKGIRYVGEYVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ACKL_DROME
Sequence: MEYPQIDLYEFLTESELQQYYNAVKNELKITNAAQFKYAADEDLRFIGLSRPEIRRLRKFYEKHFPHSYLSKIKRLLQAPGTMVKREEAPGGGSQVALDGSSASACSSLAAKNGASSPSKVPNNKHIIPADSISVNKQLGTGEFGIVQQGVWSNGNERIQVAIKCLCRERMQSNPMEFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECINYLRFTNASDVWAFGVCLWEMFSYGFQPWAALTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDMKPEQLKAVVNCTEPKKDHLLYRQGDIISVLDRNTGTPFWKGVLSTGKTGYFNPSNTVAFLEGLPSSTRDSFSRVSDHRISKRKLRTEMISKPQNDFKHTGHVGIDGATFGDIAFLGSSQNYNHVPKQIVTPYKPSEDIEQTPLLLPPTPTSPDSLQTASGYFPEGANSGGAMGTSMNPTFIPSAEHTPKLIATNGQSSFDFASGSTNPFFPNRGDDELEFGLHNYGADGKSVHSETGWRPTSRSIVDDPHEYHEISDDEIAADKLDFGPSLLDEINSMFGSISAATGSHPKSPGFDHVNNKNEITEMSAKLGQKSGDTNGNKHGHGLLPTLSKKKSSGTVKPISVKDEKILNHAIEIANEISARSMIDLVSDQTPVIHSPKRKFSFRFPHLSNNGSGDKSGGLGTSGSAHTPTHGNASPFPKKKNFTEELQSIPDIQSLIGKEGLEAYNSLIERKALLDIGPSPAATLLRHLDTDEFDLQSLHQSQRPMTLPTRGATQRVRKAELAAGLSRHNDENSNSLEACESPSYMTHGSYKFPEAQPTEQLPEPESPNPIPLPPREGKKQVKTSTKRHVRKYPLIIPANGLQRTLSKLADFGDEAAKSPEISTSSQPQPGRAIEVVAAVRPSGMRRPSRPSEREYENMPTVGKESAHTYQNLDKLTPADAAGLTDTASLQFESIMEADTSKEGILQSPDVTDGFYNFSIQKEHYNKGKDAEFEATQISGLYVNDDELRNLDIESSRRTATPCSSCSALESEHSQPDALPSTESVSEVSRFSSVDNELAGNALFKKVRASVNMAMNRKSVAETSLTSNQPGGASAKPQTEAEYFAATAARLADSNSVSCEDLLEFSDKKPKGCERGVDSDEVRIMVKVLGKDSTPNRCLGALEFINWDVHKSIKLIKLQNLVSEANLSLEASFEALQQHEWDLHTTAHKLNGLKL
What is the function of this protein?
Likely to act as a downstream effector of Cdc42 during dorsal closure, acting in a kinase independent manner with the other ACK family member Ack to positively regulate expression of the myosin zip by promoting the endocytosis of Egfr in the amnioserosa (AS).
What are the official names of this protein?
Activated Cdc42 kinase-like, Tyrosine-protein kinase PR2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.