PharMolix/UniProtQA huggingface dataset:
Protein: BIOH_NITEU
Sequence: MASIHIETTGNGPDLVMLHGWAMHSGVWDGVVESLSQRFRLHQVDLPGHGASRDCALDSLDQMTEVIADRLPGRYSVCGWSLGGQVAIRLALQAPERVQQLVLVASTPCFVRRADWPWGMEDSTLTLFMENLARDYTQTLNRFLTLQVSGSEDQARVLAWLRKSILRGQPPTPATLQAGLKILQTSDLRAELNQVSQPVLLIHGRNDVITPAGAADWMQQHLPRARLVLFPHCGHAPFLSFPEQFVSCFDAL
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIC60_ARTOC
Sequence: MLRNSIAPSRGLGSLARQRAAGPWLTTSRRSLLGKRGYSKARSAGWPYESSIRPGTAVLPTRKTSCATFTSSATLRENEPNVRSPPSPSSASAITPEGVSKPPPSSPAAQGLTSPGSSVNPPEPPKTQTGAPPPPPPPPPARKAKGKFTRFLLYLVLTTGVAYAGGVWFSLKSDNFHDFFTEYVPYGEEAVLYLEELDFRRRFPNATRHINTRPAAPRDEGEKVTIPSKSGVSWKVAEKEGGSDVSQKGRHMSALDAETSRTTDKSKSAPKRPASEDKVVSETTGTKKDKSNERVPVTDTKKPAVSLDEPRKPAVPTVSSIEPLAALQDDATIQELTKIVNGLITVINADESASKLAAPLTKAKEDFLKLGEQISRIKEEALAAAKEEINNAHLEFDRSATELVRRIDEVRAEEAAQYREEFEMEREKLAHSYQEKIKTEIERANAVAEQRLRNELVEQAIEMNRKFLNDVETLVEKERGGRLSKLSELTAQVAELEKLTAGWNEVIGANLTTQQLQVAVDAVHTALESDSMPRPFINELLAVKGLAGQDPIVNAAISSINPTAYQRGIPSTSQIIDRFRRVANEVRKASLLPEDAGVASHATSYLMSKVMFKKEVSSSGDDVESILTRTEKLLEEGNLDEAAREMNALRGWSKLLSKDWLADQWMLTQAL
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SDHA_DANRE
Sequence: MAAVCAASRVLGTKILSCKSLPAVCQANRQLHFSIYGKRGDAKISDGVSNQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEQDDWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENFGMPFSRTDDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEDGECKGVIALCMEDGSIHRFRAKNTVIATGGYGRTFFSCTSAHTSTGDGNAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGERFMERYAPNAKDLASRDVVSRSMTIEIREGRGVGPDKDHVHLQLHHLPPQQLAARLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITYKDGQDHVVPGLYACGEAGCASVHGANRLGANSLLDLVVFGRACALTIAEIDTPGEKLSPLKPNAGEASVANLDKMRYANGSTRTSEIRLNMQKTMQSHAAVFRTGDVLKEGCVKMESVYKSMDDIKTFDRGIVWNTDLVETLELQNLMLNAVQTIVSAEARKESRGAHAREDFKDRVDEYDYSKPLQGQVKKPFEQHWRKHTLSYVDPETGKVTLEYRPVIDSSLDAEDCAAIPPAIRSY
What is the function of this protein?
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL2_ACIF2
Sequence: MALIKTKPTSAGRRFVVKTIDTRLHKGNPHSALVEVQSHSGGRNNLGRVTRRHQGGGHKSHYRLVDFKRNKLDIPGKVERLEYDPNRSAHIALICYVDGERRYILAAKGMSVGDPVLSAEQTPIKPGNCMPLRGIPVGSVVHNVEMRPGKGGQIARSAGASVQLMAREGDYAQLRLRSGEVRRIHVSCRATIGEVGNEEHGSRQLGKAGATRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGQPTKGYRTRRNKRTSNMIVRRRSR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HYPA_BEII9
Sequence: MHELSLCESVIETIMDNVRTHHFSQVRRVRLTVGRFAGVETEALRFSFDVVARGTLVEGAELELLEEPGAAWCFDCSETVPLMDRLDPCPRCGGTRLHPTAGTDVMIKDLEVI
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: PETM_SYNS3
Sequence: MASEIFGIAVVFWVLIPVGLAGGALLLKLQGD
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 7, Cytochrome b6-f complex subunit PetM, Cytochrome b6-f complex subunit VII.
What is the protein family that this protein belongs to?
Belongs to the PetM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MRAZ_STAAE
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CDR2_CANAL
Sequence: MSTANTSLSQQLDEKPWVDASDNSSVQEYQGFDATASHNIQDLARKLTHGSTNGDHHSANDLARYLSHMSDIPGVSPFNGNISHEQLDPDSENFNAKYWVKNLKKLFESDSDYYKPSKLGVAYRNLRAYGIANDSDYQPTVTNALWKFTTEAINKLKKPDDSKYFDILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIAVNTYGFHIGKESQITYDGLSPHDIERHYRGDVIYSAETDVHFPHLSVGDTLEFAARLRTPQNRGEGIDRETYAKHMASVYMATYGLSHTRNTNVGNDFVRGVSGGERKRVSIAEASLSGANIQCWDNATRGLDSATALEFIRALKTSATILDTTPLIAIYQCSQDAYELFDNVVVLYEGYQIFFGKASKAKEYFENMGWKCPQRQTTADFLTSLTNPAEREPLPGYEDKVPRTAQEFETFWKNSPEYAELTKEIDEYFVECERSNTGETYRESHVAKQSNNTRPSSPYTVSFFMQVRYVIARNFLRMKGDPSIPLISILSQLVMGLILASVFFNLRKSTDTFYFRGGALFFSVLFNAFSSLLEILSLYEARPIVEKHRKYALYRPSADALASIISELPVKLLMTMSFNIVYYFMVNLRRTAGNFFFYWLMCASCTLVMSHMFRSIGAVTTTIATAMSLSTVFLLAMIIYAGFVLPIPYILGWSRWIRYINPVTYIFESLMVNEFHGREFECGQYIPSGPGFENLPVENKVCTTVGSTPGSTVVQGTEYIKLAYQFYSSHKWRNFGITVAFAVFFLGVYVALTEFNKGAMQKGEIVLFLKGSLKKHKRKTAASNKGDIEAGPVAGKLDYQDEAEAVNNEKFTEKGSTGSVDFPENREIFFWRDLTYQVKIKKEDRVILDHVDGWVKPGQITALMGASGAGKTTLLNCLSERVTTGIITDGERLVNGHALDSSFQRSIGYVQQQDVHLETTTVREALQFSAYLRQSNKISKKEKDDYVDYVIDLLEMTDYADALVGVAGEGLNVEQRKRLTIGVELVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALIMAEFDKLLFLQKGGRTAYFGELGENCQTMINYFEKYGADPCPKEANPAEWMLQVVGAAPGSHAKQDYFEVWRNSSEYQAVREEINRMEAELSKLPRDNDPEALLKYAAPLWKQYLLVSWRTIVQDWRSPGYIYSKLILVISSSLFIGFSFFKSKNNLQGLQSQMLAVFMFFVPFTTFIDQMLPYFVKHRAVYEVREAPSRTFSWFAFIAGQITSEIPFQIVVGTISYFCWYYPVGLYANAEPTDSVNSRGVLMWMLLTAFYVYTSTMGQLAISLNELIDNAANLATTLFTLCLMFCGVLAGPNVIPGFWIFMYRCNPFTYLIQAILSTGLANAKVTCAPRELVTLKPPMGETCSSFIGPYTEAAGGYFSTNSDGTCSVCRIDSTNQFLESINALFSQRWRNFGIFVAFIGINIILTIFFYWLARVPKGNREKKMKK
What is the function of this protein?
Multidrug efflux transporter.  Confers resistance to azole antifungal agents, to other antifungals (terbinafine, amorolfine) and to a variety of metabolic inhibitors.
What are the official names of this protein?
Multidrug resistance protein CDR2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NCAP_SPV1
Sequence: MATLTDVRNALQNAWTDDMKKAVKNAYRNAEKRASQGGNYAKCLEQASMQGTPYSLAAKKCAIENNLASTLSGLWGTS
What is the function of this protein?
Completely wraps the viral circular dsDNA genome to form a nucleoprotein filament (PubMed:31636205).  These interactions between the viral genome and the nucleocapsid proteins probably maintain the DNA in A-form (Probable).  This certainly protects the viral DNA under conditions such as the extreme desiccation of its host (Probable).
What are the official names of this protein?
Nucleocapsid VP1.
What are the subcellular locations of this protein?
Virion.
Protein: IF2_CLOBK
Sequence: MAKIRVYELAKELNISSKELITLLEEEFSVEVKNHMSAIEDEDANLIKELLSGKEKSEKTKEEDDEIETTAKNPIKESTNNKKPNKRDDKNEKVNTENAEDMAIITITSETITVKEISDKLEKSYAEVIKELMLMGVMASVNQEINFEMAEKLAAKFDTEILREDEDEEDDLEDILRDNEEEEYLQKRSPIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVELNGEAITFLDTPGHAAFTAMRARGAQVTDIVILVVAADDGIMPQTQEAISHCKAANVPLIVAINKIDRPGANIDKVKQELTEYGLVAEDWGGDTICVPVSAHTKEGIDDLLEMILLSSEILELKANPNRKAKGTVVEAKLDKGRGPVATLLIQNGTLRVGDSIVVGSTYGRIRAMFNDKGRNIKSAGPSTPVEILGLSEVPEAGDKFYQVKEEKTARSIADKRKEKIRDEYLQSTHKVSLEDLYNQIQEGTVKELGLIVKADVQGSVEALKQSLEKLSTGEVKVRVIHGGVGAINETDVTLATASNGIILGFNVRPDNNAIIASEKDGVDIKTYRVIYDAIEDIKSAMLGMLEPEFKEVVIGTAEVRQVYKISSVGTIAGAYIQTGKLARNAGARVIRDGIVIFESELASLKRFKDDAKEVAQGYECGLSIEKFNDIKEGDIIECFIMEEIKKKTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_SHELP
Sequence: MTTRKRPLALLILDGWGYRENTHMNAVYHANTPVLDRLNKEYPNSLISGSGLDVGLPDGQMGNSEVGHINIGSGRVVYQELTRIGKSIEDGEFDSNPAFVDAVDKAIAADGAVHIMGLLSPGGVHSHESHIQAMCKMAVARGAKQVYLHAFLDGRDTPPRSAKGSLQAFNELFAELGTGRIASLIGRYYAMDRDNRWDRVSQAYELITQGKALHLYQDAVEALDAAYGRDENDEFVASSAITDADGQVATLNDNDALIFMNFRADRARQITRSFVDPGFDGFERAVTPKINFVMLTEYAADIKAPVAYPSVDLVNTLGEVLQNNGKTQLRISETEKYAHVTFFFNGGKEEPFEGEDRILIQSPKVATYDLQPEMSSTELTDKLVEAIESTQYDVIICNYPNGDMVGHTGNFDAAVKACEAVDACIGRVVEALAKVDGECLITADHGNAEQMTDEQTGQAHTAHTSELVPLIYVGRKGEIAPNGRLSDLAPTMLTLMGQTVPSEMTGHSIITLSE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: GLYC_ASHGO
Sequence: MPYHLSESHKKLISSHLSESDPEVDAIIKDEIDRQKHSIVLIASENLTSTAVFDALGTPMCNKYSEGYPGARYYGGNQHIDRMELLCQRRALEAFHVTPDRWGVNVQSLSGSPANLQVYQALMKPHERLMGLHLPDGGHLSHGYQTETRKISAVSTYFESFPYRVDPETGIIDYDTLEKNAVLYRPKILVAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFFRRGVRSVHPKTGEEVMYDLEGPINFSVFPGHQGGPHNHTISALATALKQATTPEFREYQELVLKNAKVLETEFKKLNYRLVSDGTDSHMVLVSLREKGVDGARVEHVCEKINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFARIVGYINRAVEIARSIQQSLPKEANRLKDFKAKVEDGTDEIAQLAQEIYSWTEEYPLPV
What is the function of this protein?
Interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase, cytosolic, SHMT, Glycine hydroxymethyltransferase, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8155_DICDI
Sequence: MYIFSYEFRKIGGGSNRNNYQLNSAPAFKSSQNTSTQAKPTFSN
What are the official names of this protein?
Uncharacterized protein DDB_G0288887.
Protein: ACPS_LACH4
Sequence: MIKGVGIDSIEVERVKKIVAKGDSFAEKVLTPKEFAQYQKMKGKRKVEYLGGRFSLKESFSKAMGTGLGKYVGFQDVETLWDDLGHPVMTSTKFDGNIFPSITHDNHEIITFVVLEEK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U507_DEBHA
Sequence: MPPQSKSITYLPLLYNPFLNCIFNNPHHSKNPFRQTVQELSENHNDYTILVPPAHILHELFDPSTEKSSTKIRLHDLCYHNEDFIRSHIIKTNTTYPSITSSKSSSAIYVTMNGKQILIKNGIVFTGKGFKKSLRLKVLDINYFNSFCDYFPKGSKFMILYIEDSMFGSFDPNVPVSMQSREMDEIKIEPTLKKDQQFHDITFEKLLRSFPLLSNAVSDKFYKLFHHNNYQFRLLRTNTRKKLSSIKFEFQSMLDEAFKVVSDSVKIDTPDSEQTYHLINYILRLYPGLDLNRLVHEYVELNLYDKLWAQLIFQFDFPDNDKQNDDSDAIKILTKEKYDHLACISLNQLDVPTDKPWHINELHKRIYKAIDEFSKLSDASILNSSGKTQILKNTVNILTNNVKQISEIESMTEKTGSDGITVNADILIGLLIMVIVHARVDNLEAHLYYIKHFNSVDYTNDGYFCYILSNFDAVIYHLSSSMNDEPQYAGLVKSSALNHKFWSLIDSGDTDNLLVLLDEVQQGLGDSKLPNNHFLNSRTVQGESCLMMAVKADNSDAFNYIINYNYQWFSIDDILFDKNTTTNQSLLTVALTQESYNIITQLVEIILSNTTLEEQILYFNSVDNSGRSAGHYFHHSPNLIDQIGFLIDWELKDLNSHTPLFSLCRCYDHPDYATLLEKGFDCIYKKYGKESIDFDKHIDKMGNTLLHIILKDLSKTKLLTSETNLINVNQLNYKNLTPLDLYVKYNRLENLKELLKDDRLDFKFEDSTNFYSVFDFLGSSTAKSPTNTVLKEIEKLIYNYCFINYYPNTDTEKIAALNARFDTTKKDWALFFIKSNKIPTLNAETLDRLRKFTYIFKLDHTHSFFPDNETFWLNFPQEKSMVPIFAKFRINRIIEHVNMYMISLNFHPILTNEKIFENFFVKNRNKSTLELINDITNRQESDKRKFSNLVLGIAQVNEIDFFLRFSLTDLVNFQTTIAKFNKLVAISDIKQSDLRIVTDRMFNCLFSSNILPSVLLREYNFALTNQYKNQDSSYKELLTFTAWLELSTIELTKNIRRILLKLDDWKELHKNIKELNIELTKYEEDAPTRYATVVRDSTTEADTTDTTDATDATHASPNLANSTNGNLQQAHQLEAEAEEIADTSSSFFSFASIIENKKARYKKLLLMKAEEIKKIMKLNAELKFDHECIAAEISNFLKFKSNFINLGIKRYVRLSLCLSKIRKYELTKLLNSCKR
What are the official names of this protein?
UPF0507 protein DEHA2G04334g.
What is the protein family that this protein belongs to?
Belongs to the UPF0507 family.
Protein: SFTPA_BOVIN
Sequence: MLLCSLTLTLLWMVASGLECDVKEVCLGSPGIPGTPGSHGLPGRDGRDGIKGDPGPPGPMGPPGGMPGLPGRDGMTGAPGLPGERGEKGEPGERGPPGFPAYLDEELQGTLHEIRHQVLQSQGVLRLQGSVLAVGEKVFSTNGQSVNFDAIKELCARVGGHIAAPRSPEENEAIVSIVKKYNTYAYLGLVEGPTAGDFYYLDGAPVNYTNWYPGEPRGRGKEKCVEIYTDGQWNDKNCLQYRLAICEF
What is the function of this protein?
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.  Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
What are the official names of this protein?
Pulmonary surfactant-associated protein A, PSAP, PSP-A, SP-A.
What is the protein family that this protein belongs to?
Belongs to the SFTPA family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Protein: VGB_MYCVP
Sequence: MIPRVTSTAQTDLTEGADPYGICAADDGALWVTLVHSGAVVRLSADGGRRDYPIGAQARPSVVTVGRDGTAWFTRTGDDRITALDRTGAMTTFELASGSGPFGICVGADGAVWFTESTGDRLGRIDPDATVSYVALPEGCFPAFVAAGADGAVWATLNHADAVVRILPSADPEVIDIPTPGAAPVGITWGGDAVWFVEIATGRIGRIGDDRLVTEFALPDPACRPHAITAGPDGCWFTEWATDRVGHIGRDGTVEEYDLPSSVSEPHGITVAPDGAVWVAAESGSVVRLG
What is the function of this protein?
Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
What are the official names of this protein?
Virginiamycin B lyase, Streptogramin B lyase.
What is the protein family that this protein belongs to?
Belongs to the Vgb family.
Protein: MHPD3_PSEPU
Sequence: MTPQQREEAAQSLYQAMQSGKPIAPLRDTFPDMNVDDAYAIQSINTQRRISLGRRVVGRKIGLTSVVVQQQLGVDEPDFGALFDDMSFGDAETIPLSILHQPKVEAEIGFVLGRDLDTEQPTHQEVLQAVDYVVPALEIVGSRIADWNIKFVDTVADNASSGVYVLGSTPISPRGLDLSLVGMCLSRRGEPVSTGAGAACLGTPLNAVVWLARTMSRLGKPLRAGELILSGALGPMVAVKPGDVFECHINGVGSVRTEFESNQMNGVAA
What is the function of this protein?
Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.
What are the official names of this protein?
2-keto-4-pentenoate hydratase 3, 2-hydroxypentadienoic acid hydratase 3.
What is the protein family that this protein belongs to?
Belongs to the hydratase/decarboxylase family. MhpD subfamily.
Protein: YRF12_YEAST
Sequence: MVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCHEKASARPNDSSTMRTFTDFVSGAPIVRSLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETALKDSYRITLVPSSDGVSVCGKLFNREYVRGFYFACKAQFDNLWEELNDCFYMPTVVDIASLILRNREVLFREPKRGIDEYLENDSFLQMIPVKYREIVLPKLRRDTNKMTAALKNKVTVAIDELTVPLMWMIHFAVGYPYRYPELQLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTSDYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPDQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDVYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFCNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDILLCRDSSREVGE
What is the function of this protein?
Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.
What are the official names of this protein?
Y' element ATP-dependent helicase protein 1 copy 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
Protein: RS10_ACIBT
Sequence: MSNQRIRIRLKSFDHRLIDQSAQEIVETAKRTGAQVCGPIPMPTRIERFNVLTSPHVNKDARDQYEIRTYKRLIDIVQPTDKTVDALMKLDLAAGVDVQIALG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CTAA_METS4
Sequence: MTSAALKPLSVAPARDRAASRPRIAVRRWLFLMAALVVAMVAVGGATRLTGSGLSITEWKPVTGAVPPLSAEAWAEEFAKYRATPQYDILNRGMSLAEFQVIYAWEWGHRFLGRLIGLCFFLPLGWFWWTGRLDRRLGLGLVGLGVLGGLQGAVGWIMVASGLQPGMVAVAPIKLAAHLTLASAIFAGLVWLAAGLDRPAEAAAPRRLRLTALLLPVATLLQIALGGLVAGSKAGLTYNTWPLMDGAFIPPVSGLFAATPWIENFVDNVALVQLNHRLVAYALLALALLHALDARRARPGSGAARRAAALAGLVAAQAMLGITTLLLAVPLWAGLAHQVTAMLVLGMAVAHARIGTLARG
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4633_RHILO
Sequence: MAERPSASRQKAYRRGHRGEWLAAAALMLKGYRILARRHRTRFGEIDLIARRGDLVVFVEVKARRSLMEAMEAIGHESERRIEAAADIWLSRQADYGRLSMRFDMVAVLPWRWPVHVENAFYGRN
What are the official names of this protein?
UPF0102 protein mlr4633.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: LIGB_KLEP7
Sequence: MEEGTAMRKGGWWLALGMFSASALATCPDWPLARGRQETSRLHQQIVAWKEAYWRQGASGVSDDVYDQLTLRLAQWRQCFPGATPEDDDLPPPTGDARHPVAHTGVRKLADEDSVARWMKNKSDLWIQPKVDGVAVTLVYRQGRLVQAISRGDGLRGEAWTARARQIPALAKVMTGELADSVLQGELFLRRDGHVQQQTGGMNARAKVAGLMMRADAAAALSQLDVFIWAWPDGPSDMRRRQQLLAQAGFKYSGQYTHPVSRIEQVAQWRQRWYRSPLPFVSDGVIVREGREPPGRVWSPGKGEWLAAWKYPPASRVMQVRAIRFSIGRSGRLNVVAELEPQRLDDKRVQRVNVGSVSRWQMLDIGVGDQLQISLAGQGIPRVDAVVWRTAERHKPTPPPAKFNALTCYFATPECSEQFLSRLIWLSSKSALNVDGVGENLWRVIQQQNPMTHIFSWLALTVEQLQAVPGISAARGQHLWHQFDLVRKRPFIRWVLAMGIPVPQGALAQLESENWHLLAAKSEAQWRTLPGVGEIRARQLVAFLHHPDVVALAQWLSGQRIPGF
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: ATPA_LACDA
Sequence: MSIKAEEISSLIKQQLEHYDDKLDIEEVGVVTYVGDGIARAHGLNNVLSSELLQFDNGAYGIAQNLESNDVGIIILGKFDDIREGDRVKRTGRIMEVPVGDALIGRVVNPLGQPVDGLGEIKTDKTRPIESKAPGVMQRQSVNQPLQTGIKAIDALVPIGRGQRELVIGDRKTGKTSLAIDTILNQKGQDVICIYVSIGQKESTVRAQVETLKKLGAMDYTIVVEAGPSEPAPMLYIAPYSGIAMGEEFMYAGKDVLVVFDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKLSKELGGGSLTALPVIQTEAGDISAYIPTNVISITDGQIFLQSDMFFSGTRPAIDAGASVSRVGGAAQIPAMKKVAGTLRTDLASYRELESFAQFGSDLDQATQAKLARGRRTVEVLKQPLHKPVAVEKQVVLLYALTHGFMDAVPVDDIARFEQELYTDFDANHADLLAEIKSTGKLPDENKLQEALQQFASSFSSSNK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: STATB_CAEEL
Sequence: MSSVVSDQMDIESSSAFSPAEPVVDGAFVSKHNLSAEAYQGFKECADSLLSGKIAQNEQLPFIQRTLQICENVILNFEDEKQHLMSDVLLVWAMKQQKLSIATLHTQQLHYKELDLINLQFEYFGELLQQTLSGLDYLKQYYPNVGFEEVHSKVRNLTHYFLYYSIIVSRQPPSVIVKCGEAENHRRSRFWFNTEIRILGGSAFGIDTNNENSNVNCYLITDETAKQLLNNAYLDIFESEEFCIEPNTSTFQKKDARGIKAKFDDMKVAKKVALRRDSVATKRYCLCYNIQLQTNCGIELVGKKVSLPFAVLVGPKADVEAKLFLERSFADLVRHPLSDIPTHVSCAEMADALEMKFQAIIETPQKNTDGPSVVQPRKFNMQTKQHLVMRMKPNNQGFLPLDNFMKLPVAEEFQHKKSASAEGDWKLVPFYDWFFKLAEITNKYLYSMWYDGLVYGFCSKEDAENILRCIPRSVLLVRFSDIEYGKIKISVKNRNGEIRHHWYEHADLNARSLNSELLSNHKFSDVDLIYPDIDLEVALGGRNKPRIRLPRNLAPDEIYFDNQGAAT
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription (By similarity).  By positively modulating expression in the epidermis of antimicrobial peptides, such as nlp-29, plays a role in resistance to fungal infection and in the response to physical wounding and phorbol ester PMA treatment (PubMed:22470487, PubMed:21575913).  Functions cell autonomously in the epidermis, in concert with sodium-dependent transporter snf-12, probably acting at vesicular membranes, downstream of a p38 MAPK/pmk-1 pathway.
What are the official names of this protein?
Signal transducer and activator of transcription b, Zinc finger protein STAT-B.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.