PharMolix/UniProtQA huggingface dataset:
Protein: NUSG_TREPA
Sequence: MAKEWYILHTFSGREARVERAVRMLVEHARIPTNVIFDIKIPEELLTEVKDGKKRVVRRKFFPGYLLVEMDLPEVDWRIVCNEVRRIPGVSGFLGSSGNAKPQAVSADEARRILQKAGEIKGDRTPRIAQTFLVGQQVRIVEGPFATFSGEVEEVMSERNKVRVAVTIFGRATPVELELVQVEAL
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: BAMC_SHEON
Sequence: MLKKVTPLFLVAAVAACSSPLERRQANGGEDYVQAEQAPMLKIPEGLKTPPYNKEYDVPALGPKANPALVGKNLDIRPPLQVLPMAEGTHVEEGSDNIKIVVESIDNNVDLKQEIFTNLDDFFAKQAIPIRSRDFDKGSIETDWIESREVLESSLWGSDKEYLLRQRYRFDVETRPHGRTANIVIHLVEHEEFYDGKEQKVMLSGEDKQRYTIDMLNSAIAYMSVKREQTIQANRLKQTLGINVDLITPEEGAAYWSAKAAYKQVWDRLRIVLPEMGFEISDMDSAKGLYFIKFTDNSGFWSSLWNNNQLSLKEGSYRLLLEDGDTPDETKIWLRDAEDQPLSNDVVSKVYESLSSLMKEERKLR
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamC.
What is the protein family that this protein belongs to?
Belongs to the BamC family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GTD2A_HUMAN
Sequence: MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYMERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEKSLKNFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLNYIPKIAELQTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT
What are the official names of this protein?
General transcription factor II-I repeat domain-containing protein 2A, GTF2I repeat domain-containing protein 2A, Transcription factor GTF2IRD2-alpha.
What is the protein family that this protein belongs to?
Belongs to the TFII-I family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHRC1_HUMAN
Sequence: MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYLKMLKEEKREEDEENDNDNESDHDEADS
What is the function of this protein?
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1.  Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (PubMed:14759371).
What are the official names of this protein?
Chromatin accessibility complex protein 1, CHRAC-1, Chromatin accessibility complex 15 kDa protein, CHRAC-15, HuCHRAC15, DNA polymerase epsilon subunit p15.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_PSYA2
Sequence: MALSKDDVLNAIAEMSVMDIVELISAMEEKFGVTAAVAAAPAAAGPAAAAAEEKDEFDVVLASFGEKKVGVIKAVREATGLGLKEAKDLVESAPASIKEGVNKAEAEELKKKLEEAGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: NRDI_MYCPA
Sequence: MDSTGRNLVYFSSVSENTHRFVQKLGIPAIRIPLHGRIEVDHPYVLLLPTYGGGRATPDLNAGGYVPKQVIAFLNNEHNRSLIRGVIAAGNNNFGAEFAYAGNVVSRKCGVPYLYRFELMGTQDDVDAVRAGLAEFWKEQTCHQPSLQSL
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: RL1B_YEAST
Sequence: MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  uL1 forms part of the L1 stalk, a mobile element that plays a role in evacuating the exit-site tRNA.
What are the official names of this protein?
60S ribosomal protein L1-B, L10a, Large ribosomal subunit protein uL1-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_BUCBP
Sequence: MLKGKFIVIEGIEGSGKTTICKTLKNILYEHGIKNVICVRDPGSTPLAEKIRSLLITKDKNEYMVNETELLLFYAARIQLIKNIIQPALNKGVWVISDRYFLSSLAYQCAGRKIKEEIVLLLQSLFLKNFNPNITFYLDVTPEIGLNRIKNRNEIDRIEQNTKFFFNNVRNKYLNLIKTKPGIIKINANRKIDKVKHSCKQQMLSWLNTENL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: COBM_SINSX
Sequence: MTVHFIGAGPGAADLITVRGRDLIGRCPVCLYAGSIVSPELLRYCPPGARIVDTAPMSLDEIEAEYVKAEAEGLDVARLHSGDLSVWSAVAEQIRRLEKHGIAYTMTPGVPSFAAAASALGRELTIPAVAQSLVLTRVSGRASPMPNSETLSAFGATGSTLAIHLAIHALQQVVEELTPLYGADCPVAIVVKASWPDERVVRGTLGDIAAKVAEEPIERTALIFVGPGLEASDFRESSLYDPAYQRRFRGRGE
What is the function of this protein?
Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5.
What are the official names of this protein?
Precorrin-4 C(11)-methyltransferase, Precorrin-3 methylase.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: MPS2_YEAS1
Sequence: MSNGAFDAIFEYAWGQIDKPISGDFIYGKDLPKLIEIIENIFQKAQKSGSYELRLPLFSEINKDLFRTFSNTKTFFKIHKEEFDDIFFNLVNHPLREILENAFIGVDSIPSDFIVSMNLNSPSKFLVENKSKNTEGAGISTSRKKLTESPIKLLSRNNIGKALEVQVEELKRELTAKQSLLQENERQVSELKIRLETYQEKYASIQQRFSDLQKARQVEDNQNSSRTSDPGSPLVTGIDQKAILEEFRRRLQRQTDTISFLKDQIRRERGLNCSNDKVSHSKRKHATTDGDGTFKNFISAVPSNIWVKATIRIIVCFALLAGVLPYIRKYVYAHDTPSQNSRLQLSWWENSGILSKIVWFFEDQTDLETEYRSNANVDDAYSRVFGI
What is the function of this protein?
Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
What are the official names of this protein?
Monopolar spindle protein 2.
What is the protein family that this protein belongs to?
Belongs to the MPS2 family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: LGT_DEHMC
Sequence: MFEINVDPVAFSIGSLVVKWYGIMMALGVVALVSWIFWRIKRGANISYDTVLTAAIIAIPSGIVFAKLLHVIDAWEYYSLNPGAIFSGEGLTIFGAIIGATIGLWIYSRYSHFNLGYLLDVAVPGILLGQAIGRVGCLLNGCCYGEFGGTGCSVIYTNPATAAPYGVEVAPTQAYEIIFLLCLLTFSLFIAKKLRPDGQLFLLYISLYAAWRVAIGFVRVNDDFALGLEQAQVVGLILMAVAVPLFIYRLRKQKQTDKIT
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH044_HUMAN
Sequence: MRKNESYLNQPAPPIPIPTLSLMGGCREHFENHWKGRARWLMPVIPALWEAKAGRSPEVRSSKPAWPTWRNPIFTKNTKISQVLELFLNYQSLICALEKQKRQKGSLAIFCWSFQGGCVSKRPDVPSLKSQKPKRKRITGRKRLSKGFWSLLFSNLGRF
What are the official names of this protein?
Putative uncharacterized protein C8orf44.
Protein: CA216_HUMAN
Sequence: MFAIQPGLAEGGQFLGDPPPGLCQPELQPDSNSNFMASAKDANENWHGMPGRVEPILRRSSSESPSDNQAFQAPGSPEEGVRSPPEGAEIPGAEPEKMGGAGTVCSPLEDNGYASSSLSIDSRSSSPEPACGTPRGPGPPDPLLPSVAQAVQHLQVQERYKEQEKEKHHVHLVMYRRLALLQWIRGLQHQLIDQQARLQESFDTILDNRKELIRCLQQRAAPSRPQDQA
What are the official names of this protein?
UPF0500 protein C1orf216.
What is the protein family that this protein belongs to?
Belongs to the UPF0500 family.
Protein: HFQ_COLP3
Sequence: MAKGQSLQDPFLNALRRDRIPVAIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSRAVNTAPVPGPDDQSSDA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: HDT1_ARATH
Sequence: MEFWGIEVKSGKPVTVTPEEGILIHVSQASLGECKNKKGEFVPLHVKVGNQNLVLGTLSTENIPQLFCDLVFDKEFELSHTWGKGSVYFVGYKTPNIEPQGYSEEEEEEEEEVPAGNAAKAVAKPKAKPAEVKPAVDDEEDESDSDGMDEDDSDGEDSEEEEPTPKKPASSKKRANETTPKAPVSAKKAKVAVTPQKTDEKKKGGKAANQSPKSASQVSCGSCKKTFNSGNALESHNKAKHAAAK
What is the function of this protein?
Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Required for histone H3 'Lys-9' deacetylation.  Involved in rRNA gene silencing in nucleolar dominance.  Seems to be implicated in the regulation of genes involved in seeds development.
What are the official names of this protein?
Histone deacetylase HDT1, HD-tuins protein 1, Histone deacetylase 2a, AtHD2A.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase HD2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PSBB_SACHY
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVSGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSISGGTVTNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLAGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQAVNPAWGAEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSDGLAENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRDKEGRELFVRRMPTFFETFPVVLVDEEGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHATFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGTFQKVGDPTTRRQAA
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LPPB_MYCTO
Sequence: MIAPQPIPRTLPRWQRIVALTMIGISTALIGGCTMGQNPDKSPHLTGEQKIQLIDSMRHKGSYEAARERLTATAQIIADRVSAAIPGQTWKFNDDSYGQDFYRNGSLCKELSADIARRPMAKPVDFGSTFSAEDFKIAANIVREEAAKYGVTTESSLFNESAKRDYDVQGNGYEFNLGQIKFATLNITGDCFLLQKVLDLPAGQLPPEPPIWPTTSTPTP
What are the official names of this protein?
Putative lipoprotein LppB.
What is the protein family that this protein belongs to?
Belongs to the mycobacteriales LppA/LppB family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TBCB_DICDI
Sequence: MSSTKSDFEIIREYIIGDGKDISVGKAPEGNVRLEITHSVLTGESLGTNNFKNFSLDLKIKDFKEKLYRFVGTEPKYMELILRDENKVNDICKIDDDDDKTLGSYEPKDGMNVHIIDKDPNNFVSELQDISKAPKPVISEEDYNKREGTYKKWKEENQLKKENDTTATTVTATTTTTNNATDTEIEIKVGDRCKVISDDPTNYDERLGKVQYVGTVEFSSGVWIGVELDLPLGKNDGSVKGKQYFQCSPKYGCFAKPKNVLVGDYPEEEI
What is the function of this protein?
Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer.
What are the official names of this protein?
Tubulin-specific chaperone B, Tubulin-folding cofactor B.
What is the protein family that this protein belongs to?
Belongs to the TBCB family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: UBX_DROFU
Sequence: MNSYFEQASGFYGHPHQASGMAMGSGGHHDQTTASAAAAAYRGFTLPLGMSPYANHHLQRTTQDSPYDASITAACNKIYGDAGSAYKQDCLNIKADAVNGYKDIWNTGGANGGGGGGGGGAATAGNTSNGSNAPNAANGQNNAGGGGMPVRPSACTPDSRVGGYLDTSGGSPVSHRGGGSAGGGNGTAGGVPQNSASGVGGGVGAGTAWNANCTISGAAAAQTAAASSLHQPGNHTFYPWMAIAGESTADPIK
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Binds the consensus region 5'-TTAAT[GT][GA]-3'.  This homeotic protein controls development of the cells in the posterior thoracic and first abdominal segments.  It activates the synthesis of the decapentaplegic (DPP) growth factor (By similarity).
What are the official names of this protein?
Homeotic protein ultrabithorax.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDUL_ALKMQ
Sequence: MKEEQIKQIVEQVIKTFEEAQSVPMEVPVEVSARHIHLSKEHISLLFGSEDQLSIIKELSQPGQFQYDKRVTLIGPKGSIGNVAILGPSRDETQVEISYTDARALGIKPPLRESGDLQDTAGIIIATGHKAINLEGGVMIAKRHIHMTPKDAEVFHVKDGEHVKVRIESKRPIVLEDVLVRVNEKYGLSMHIDHDEGNAAAYQPGTTGKMIK
What is the function of this protein?
Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
What are the official names of this protein?
Phosphate propanoyltransferase, Phosphate acyltransferase PduL, Phosphotransacylase PduL, PTAC, Propanediol utilization protein PduL.
What is the protein family that this protein belongs to?
Belongs to the PduL family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: GRM2_RAT
Sequence: MESLLGFLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHSDAPTAVTGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSERAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEERFHCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTHLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTDDEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSFIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFVFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAPRASANLGQGSGSQFVPTVCNGREVVDSTTSSL
What is the function of this protein?
G-protein coupled receptor for glutamate.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Signaling inhibits adenylate cyclase activity.  May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
What are the official names of this protein?
Metabotropic glutamate receptor 2, mGluR2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Synapse. Cell projection, dendrite.
Protein: SYY_LISW6
Sequence: MNIIDELEWRGAIYQQTDEEGLRKWVEEKQISLYCGIDPSGDSMHIGHLIPFMILRRFQNAGHRPIILVGGATGTIGDPSGKKEERKLQSMEQISRNVESLRVQLGKIFDFEGDSAASMVNNYDWTKDVSILDFLRDYGKEFNVNTMLSKDIVASRLEVGISFTEFAYQILQAMDFNHLYEFNDCRLQIGGSDQWGNITAGLDLIRKKQGENAKAFGLTIPLLTKADGTKFGKSEGGAIWLNPEKTTPYEFYQFWINTDDRDVVKYLKYFTFLTETEIDELAKKVEEEPHLRAAQKTLAAEMTKFVHSEEALEQALKISKALFSGDVTALTADEIEQGFKDVPTFVAEDAEVNLVDWLVSLGIEPSKRQAREDVTNGAIYINGERQQNVEKVIDASDRIENKFTIVRRGKKKYFLVSYK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGIS_ECOLI
Sequence: MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPGTLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQWSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKATDDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDQWVVNEKITARKNPKYRDAQHTVLQQVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIEKSLPGELRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATTLTPPEVKGFSATTFDELQKPMSERVAMAKALLKQAGYDASHPLRFELFYNKYDLHEKTAIALSSEWKKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASSFLNTLKSDSEENVGHWKNAQYDALLNQATQITDATKRNALYQQAEVIINQQAPLIPIYYQPLIKLLKPYVGGFPLHNPQDYVYSKELYIKAH
What is the function of this protein?
Probably part of a deoxycholate transport system.  Its expression in the presence of deoxycholate in a ygiS deletion mutant increases intracellular deoxycholate levels and decreases cell growth; higher expression in the presence of deoxycholate inhibits cell growth completely.  Bile acid detergents such as deoxycholate are important for host defense against bacterial growth in the gall bladder and duodenum.
What are the official names of this protein?
Probable deoxycholate-binding periplasmic protein YgiS.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSD2_ARATH
Sequence: MGNGNSREAKESRRSRLRHKLQKFRIHRRHLRSSRNSAGMVIQRTVSAEDFSGIALLTLIGAEMKFKDKWLACVSFGEQTFRTEISDTTQKPIWNSEKKLLLEKNGPSLARVSVFETNRVARNKIIGYCELDIFDFVVQEPESTCKSFNLLDPTSSNVVGSIFLSCAIEDPVETERRFAKRILSIVDYNEDGQLSFSEFSDLIKAFGNLVAANKKEELFKAADLNGDGVVTIDELAALLALQQEQEPIINNCPVCGEALQVSDKLNAMIHMTLCFDEGTGNQVMTGGFLTDRQASYGWMFKLSEWTHLSTYDVGLNTGSSASYIVVIDRKSKRLVEELIDSKIVLSMRAIYQSKIGLRLMDQGAKEILQRLSEKQGKKMSSVESAQKIPRFLEFFKDQINMAEVKYPLQHFKTFNEFFIRELKPGARPIACMNRNDVAVCAADCRLMAFQSVEDSTRFWIKGKKFSIRGLLGKNVNPNAFLDGSLVIFRLAPQDYHRFHVPVSGVIEQFVDVSGSLYTVNPIAVNSKYCNVFTENKRTVAIISTAEFGKVAFVAIGATMVGSINFVRKEGEHVKKGDELGYFSFGGSTVICVFEKDAIGIDNDLLVNSGRSLETLVSVGMQLGVSTRTFARSTLI
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.  Contributes only to a minor proportion of PtdEtn production.
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme 2.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein. Note=Tonoplast.
Protein: RS21_SHEAM
Sequence: MPIVKVRENEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAVKRLAKKLSRENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RQKA_DEIRA
Sequence: MPLTPGTLLAGRYELLALLGEGGSAQVYRAQDGLLGREVALKVMHDYLPESDRSRFLREVRTLARLTHPGVVPVLDLGQEPEAGRPFFTMPLLTGGPITRLGPLEDAPGPLARFLTAAAFASRALHHVHSHGIVHRDLTPGNVLLDDTGLPRIMDFGLVALSEQTRHLTRSGVTLGTPAYMAPEQAKGGGVDARSDLYALGAVLYRVACGSPPFVGDSDQSVLYQHVYEPVPDPRDLNPAVPDAVARVLLWLLAKRADRRPQSGAALAHLWALARRDLWTTHARGQYRGGRARTGEHPDGPARVSDMQELWSVALPGEVTWPAAVVGEGDLVAVGTRGGQLVLTHTSGRPFATYAARDEVTAPATLIGGHVLYGAWDGTLRRVELQSGSEVWRHQARAEFTGAPTVWGGRLLAPSRDGHLHALSLRTGELAWAYRAGGSLAASPLVWAGAALQCDETGWLHALDARSGTPLWKVEVGTVHATPALLPGPPGTATLVIATWEGEVHAIGLEVQNGRAALAGEDAIRWTYDVEDEVWASPALTALDLPPDSGAAPDASAAPGGVVVVAGWGGKVRGLRLADGEDLWERTLDGRVTASPVISAGLVFLATEGGELLALDVRNGEVRWTCRERSGVQATPLAASGTLYVAFMDGTLRAYRNAHPEWRSEQEG
What is the function of this protein?
Plays an important role in radiation resistance and DNA double-strand break (DSB) repair.  Involved in transcriptional regulation of genes important for bacterial stress response.  Phosphorylates PprA in vitro.
What are the official names of this protein?
DNA damage-responsive serine/threonine-protein kinase RqkA, Radiation and pyrroloquinoline quinone inducible protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RL31_NICGU
Sequence: MSDKTKGRKEEVVTREYTINLHKRLHSCTFKKKAPTAIKEIRKFAQKAMGTKDVRVDVKLNKQIWSRGIRSVPRRVRVRIARKRNDDEDAKEELYSLVTVAEIPAKGLKGLGTKIIEDED
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: FOLD_HERA2
Sequence: MTALLLDGRGLAKELKAQISQQGAEFKARTGYAPQLVVIQVAGNAASDWYVRSIRRSCEGVGFGFALQRLPETSDQATLEAAIQQASNDPAIHGIIIQMPLPSQLSADGAVAALNPQKDVDGLHPTNAGRLAQGLTALVPNTPAGGMALLDRYQINLAGKHAVVVGRSNVVGKPLAQLLLARHATVTICHSRTANLAEVIRQGDIVAAAVGKAGLVTGEMLKPGAVVLDFGINEVAEGQVVGDVDWESASKVASAITPVPGGTGPVTNMMLLQNTLQAAQSLAEQA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.