PharMolix/UniProtQA huggingface dataset:
Protein: RNY_CLONN
Sequence: MIITILIAIFVIIYVRKNISQAKIAEAEAKSKKIIIDSEKNAEAIKKEAILEAKEEVHRIRNDFEKESRERRNEIQRLERRIIQREELLDKKSEAIENKEEVLNKKQQDINEKAASIDELYDKQREELEKLSNLSSDEARELLLEETKKEIRHDLAVMIKEMENKAKEEADKKAKEIISTAIQRCAADHVAESTVHVVSLPNDEMKGRIIGREGRNIRALETLTGVDLIIDDTPEAVILSGFDPIRRQVARIALEKLIIDGRIHPARIEEMVEKAKQEVENDIKEEGEQATFETGVHGLHQELVKLLGRLKYRTSYGQNVLKHSMEVAYLAGLMASELGMDPTLAKRSGLLHDIGKAVDHEIEGPHALIGSEMAKKYHESSVVVNAIAAHHGDVEYESIEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANSYEGVEKSYAIQAGREVRIMVKPEDIDDYGCIEMSKNIVKRIESELEYPGQIKVNIIREVRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
Protein: UREF_ACTPL
Sequence: MGQLGALLHLVDPTLPIGGFNHSNGLETFVQQGKVNSRASLEEYVQTQLMQNWIYNDGAYLSLAFDAMANHDLDRLLALDQELAASKIARESREGSYKLGVRLLKIFIRYENHPLLSEFQQAVSEKRCQGYFPIVFAMVAQAMNLDKAETLYAFYYNAAVGVVTNGVKLVPLSQMDGQDILFALRTPLAQAVENSLNPDLDWLGAATLASDIRSMQHEQLYTRLYMS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5NT1A_MOUSE
Sequence: MEPGQPREAREPGPGAETAAVPRWEEAKTFYDNLSSKKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKRLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADADKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRRAAAAKQSLGAQ
What is the function of this protein?
Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside (By similarity).  AMP is the major substrate but can also hydrolyze dCMP and IMP (By similarity).
What are the official names of this protein?
Cytosolic 5'-nucleotidase 1A, cN1A, 5'-deoxynucleotidase, Cytosolic 5'-nucleotidase IA, cN-IA.
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase type 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2X1_XANCR
Sequence: MTSAPPRWTTAELAEDAATSAAQFRTERLAVTDSWGTHYNQARGKFELLFKKLSDLNPEAITDDNLAEAYGLGLGEALRYLAGPPISDDDLQVIADVESIAPGVLKKNAEALRKVFGVIERVIDPHRFPWMETGGMPTEQQREAALLASSVLLAAQRIATERRNEGKDNQETMVKDYLRTLGFTEAPAAAINTIVKGPQAMQFCAECQLGERKADVVVRLHDTRLMAIECKVSNSSTNSVKRLNNDAAVKAEYWIKQFGTAQVVPSRSLVSSRY
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GTCGAC-3' and cleaves after G-1.
What are the official names of this protein?
Type II restriction enzyme XamI, R.XamI, Endonuclease XamI, Type-2 restriction enzyme XamI.
Protein: CFIS2_ARATH
Sequence: MAMSQVVNTYPLSNYSFGTKEPKLEKDTSVADRLARMKINYMKEGMRTSVEGILLVQEHNHPHILLLQIGNTFCKLPGGRLKPGENEADGLKRKLTSKLGGNSAALVPDWTVGECVATWWRPNFETMMYPYCPPHITKPKECKRLYIVHLSEKEYFAVPKNLKLLAVPLFELYDNVQRYGPVISTIPQQLSRFHFNMISS
What is the function of this protein?
Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing.  Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition.  NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates.  The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA.  Binds to, but does not hydrolyze mono- and di-adenosine nucleotides.  May have a role in mRNA export.
What are the official names of this protein?
Pre-mRNA cleavage factor Im 25 kDa subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. CPSF5 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles.
Protein: PA2GE_HUMAN
Sequence: MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids (PubMed:10681567, PubMed:11922621, PubMed:28883454).  Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), releasing various unsaturated fatty acids including oleoate, linoleoate, arachidonate, docosahexaenoate and lysophosphatidylethanolamines in preference to lysophosphatidylcholines (PubMed:10681567, PubMed:28883454).  In response to high-fat diet, hydrolyzes minor lipoprotein phospholipids including phosphatidylserines, phosphatidylinositols and phosphatidylglycerols, altering lipoprotein composition and fat storage in adipose tissue and liver (By similarity).  May act in an autocrine and paracrine manner (PubMed:11922621).  Contributes to lipid remodeling of cellular membranes and generation of lipid mediators involved in pathogen clearance.  Cleaves sn-2 fatty acyl chains of phosphatidylglycerols and phosphatidylethanolamines, which are major components of membrane phospholipids in bacteria (PubMed:11922621).  Acts as a hair follicle phospholipase A2.  Selectively releases lysophosphatidylethanolamines (LPE) and various unsaturated fatty acids in skin to regulate hair follicle homeostasis (By similarity).  May regulate the inflammatory response by releasing arachidonate, a precursor of prostaglandins and leukotrienes (PubMed:11922621).  Upon allergen exposure, may participate in allergic inflammatory response by enhancing leukotriene C4 synthesis and degranulation in mast cells (By similarity).
What are the official names of this protein?
Group IIE secretory phospholipase A2, GIIE sPLA2, sPLA2-IIE, Phosphatidylcholine 2-acylhydrolase 2E.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=Through binding to heparan sulfate proteoglycan, may be localized to cytoplasmic compartments enriched in anionic phospholipids.
Protein: VM3M_ECHML
Sequence: FPPHKGKFDKKFIELVIIVDHSXXTYK
What is the function of this protein?
This carinactivase-like calcium-dependent prothrombin (F2) activator activates prothrombin via recognition of the calcium ion bound conformation of its gamma-carboxyglutamic acid (GLA) domain, and the subsequent conversion of prothrombin to active thrombin is catalyzed by the catalytic subunit.
What are the official names of this protein?
Zinc metalloproteinase multactivase catalytic subunit, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIId sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HUTH_SALA4
Sequence: MNTMTLTPGQLSLSQLYDVWRHPVQLRLDANAIDGINASVACVNDIVAEGRTAYGINTGFGLLAQTRIADEDLQNLQRSLVLSHAAGVGDPLDDAMVRLIMVLKINSLARGFSGIRLSVIEALIALVNAGVYPLILAKGSVGASGDLAPLAHLSLTLLGEGKARWQGEWLPAQTALKKAGLEPVALAAKEGLALLNGTQASTAFALRGLFEAQELFASAVVCGALTTEAVLGSRRPFDARIHAARGQQGQIDVARLFRHLLTDTSAIAESHHHCHKVQDPYSLRCQPQVMGACLTQLRQTKEVLLAEANAVSDNPLVFADAGEVISGGNFHAEPVAMAADNLALAIAEIGALSERRIALMMDKHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALAHPHSVDSLPTSANQEDHVSMAPAAGRRLWEMAANTRGIIAVEWLAACQGIDLREGLTSSPLLEQARQTLREQVAHYTQDRFFAPDIECATALLAQGALQRLVPDFM
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M28P2_ARTBC
Sequence: MRFLISSLLSGLALLTSLHAFVLALPREYSISMSNPFHESLFSCPAASWPRVKLGSENTPQEPSKDLRKILSQISPKRIETTIRKLVSFGTRHTLSTQTNATYGIGAAREWIESEFQRYANASDGRLTVKVVGYDQQADGNRIPFPVRISDVVATLKGEGDPERVYVVSGHYDSRNSDPLDYKGIAPGANDDASGVAVSLELARVMSQRDLPRPKATIVFAAVAGEEQGLYGANFLAQSFRNSSTNVEGMFTNDIIGSSTADDGTKEPHVIRLFAQGIPPLNVENQAMRERRIMIGGDNDTPARQLARFVKETAENKHTDMEVSVIYRLDRYLRGGDHRPFLEAGYPAARFTEPNGNYAHQHQDIRIDKDPKTGKDIQYGDLPEFCDFDFISRVGKVNAAALWNLAMSPGMPRNVRVNTTALSNDSKFSWDPPAGGNALVGGYEIVWRSTTAPFWTHKMDVGMVQEATIDLSKDNVVFGIRARGKNGERGVAVLPFP
What are the official names of this protein?
Probable zinc metalloprotease ARB_04732.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACEK_ECO45
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIVRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPLPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRFV
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD10_DICDI
Sequence: MSGTKFRTGGTKEDDLLEFVKVGKLLEVKDLIENQGVKADCKDEDERTPLHWAAAKGQISVAQYLMDNCKCSPNTNDDGGWTPLTSATSAGHTHMVKLLLEFGADPNTVNDSKRTPLHYASSKGRSDIVDLLLTHGAKNRKDDTGSAPIHRASSNGSVATVERLLKGEANINSTNNEGDTPLHIAAEYNHEDVVECLLKHGADTTIENKDSKTPIDMSSSQTIKYLIKEFKK
What is the function of this protein?
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC).
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28.
Protein: GLMM_CROS8
Sequence: MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKVIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIEGTKLPDEVEEAIEAELEKEISCVDSAELGKASRIVDAAGRYIEFCKGTFPNELSLNGLKIVVDCANGATYHIAPNVLRELGARVVTIGSEPDGLNINEKCGATDVRLLQERVVAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQILYIIAREGLRQGQLRGGAVGTLMSNMGLEVALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAALQVLTAIARNHMSLHDLCSGMKLFPQILVNVRFTPGSGDPLEHDTVKAVTEEVEQALGKRGRVLLRKSGTEPLIRVMVEGENEAQVTEFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SPI1_VACCC
Sequence: MDIFKELIVKHPDENVLISPVSILSTLSILNHGAAGSTAEQLSKYIENMNENTPDDNNDMDVDIPYCATLATANKIYGSDSIEFHASFLQKIKDDFQTVNFNNANQTKELINEWVKTMTNGKINSLLTSPLSINTRMTVVSAVHFKAMWKYPFSKHLTYTDKFYISKNIVTSVDMMVGTENNLQYVHINELFGGFSIIDIPYEGNSSMVIILPDDIEGIYNIEKNITDEKFKKWCGMLSTKSIDLYMPKFKVEMTEPYNLVPILENLGLTNIFGYYADFSKMCNETITVEKFLHTTFIDVNEEYTEASAVTGVFTINFSMVYRTKVYINHPFMYMIKDTTGRILFIGKYCYPQ
What is the function of this protein?
Plays a role in mediating viral host range.  May act to inhibit a caspase independent form of apoptosis to allow efficient virus replication in infected cells.
What are the official names of this protein?
Serine proteinase inhibitor 1, Serp-1, Serpin-1.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: SURA_PHOPR
Sequence: MKKWKSSLLGIAIWSLAASSMAAPKELDKVVTLVNDSVILQSDVNAMLQTVRINAAEQNQPLPDDALLTEQVMEKLIIETLQLQQAEQFGIRIDDTRLDQAVAEIAKERELTIPQLQKELEKSGISYSIFREQMRRDMTASEARTIQVRRRINILPQEVEMLAEQLNKQTLQTVQFNISHIQLRVEEGATKEQREETQQQAQQIVDELKNGADFANLAYSYSKGPKALQGGEWGWMRQEEMPTIFADQIKSNGKGAIIGPFRSGVGYHIIKVNDVKGLETVSVTEVNARHILIKTSVILSDDGAKRQLEKARQDILAGRQTFADEAQKLSSDPGSAANGGELGWQTPDLYVPEFKDKIETLPKGTISEPFKTVHGWHIVEVLDRRNVDRTDAAMKNRAYRILFSRKFNEEAQAWLQELRAGAYIEQLGTNDDQG
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: ULAB_SHIBS
Sequence: MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKAHFPQDVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIB component, Ascorbate-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1143_MOUSE
Sequence: MSKRNQVSYVRPAEPAFLSRFKERVGYKEGPTVETKKIQPQLPDEDGNHSDKEDEQPQVVVLKKGDLTAEEVMKIKAEIKAAKTDEEPPPADGRIVYRKPVKRSSDEKCSGLTASSKKKKTNEDDVNKQSSVRKNSQKQIKNSSLLSFDSEDENE
What are the official names of this protein?
Uncharacterized protein KIAA1143 homolog.
Protein: VKTHD_DENAN
Sequence: AAKYCKLPVRYGPCKKKIPSFYYKWKAKQCLPFDYSGCGGNANRFKTIEECRRTCVG
What is the function of this protein?
Serine protease inhibitor homolog that blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type serine protease inhibitor homolog delta-dendrotoxin, Delta-DTX, Dendrotoxin delta-DaTX, Protease inhibitor K, Toxin C13S1C3, Venom basic protease inhibitor K.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: HRCA_LYSSH
Sequence: MLTNRQLQILQVIIDDFILSAQPVGSRQISKKQGITFSPATIRNEMADLEELGYLEKTHTSSGRVPSEKGYRFYVDHLLSPQGINSRDIQQIQSIFNDRLVEVEHIIRKSANILSELTSYTSILLGPDVQRHRVKRFSIVPLSSDTAVAIIVTNNGHVENRLFNLPPDFTASDLEKMVNILNDRLIGVSLEELHKSLEAEVLAVLQQHVQSADDFYPRTRNSDNAIIQKAKIFYGGKTNMFNQPEFHDLNKVRMILDLMETTSQVQSLFHPNESGIHIRIGSENKQLEMENCSVITTTYSIGDDQQGAIAIIGPTRMDYKRVVALLDVIRLDLTQAFTKNRSE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: APH1_SCHPO
Sequence: MPKQLYFSKFPVGSQVFYRTKLSAAFVNLKPILPGHVLVIPQRAVPRLKDLTPSELTDLFTSVRKVQQVIEKVFSASASNIGIQDGVDAGQTVPHVHVHIIPRKKADFSENDLVYSELEKNEGNLASLYLTGNERYAGDERPPTSMRQAIPKDEDRKPRTLEEMEKEAQWLKGYFSEEQEKE
What is the function of this protein?
Asymmetrically hydrolyzes Ap4A to yield AMP and ATP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase.
Protein: Y4KN_SINFN
Sequence: MPADRCKGWLGLGAVQASPINWIGRYSFGTPEEEVSLSNDAEPEGIGAIDQLYDILEMLEEDIKDLEGARRERVNVFLYQGIFEAISFLDELGMAGRIGLSAMELDKFQRMSGTIDNAVLRQMTGRLKSLLREANCLYDR
What are the official names of this protein?
Uncharacterized protein y4kN.
Protein: RACC_ECOLI
Sequence: MITNYEATVVTTDDIVHEVNLEGKRIGYVIKTENKETPFTVVDIDGPSGNVKTLDEGVKKMCLVHIGKNLPAEKKAEFLATLIAMKLKGEI
What are the official names of this protein?
Protein RacC.
Protein: PA2A4_TRIGA
Sequence: HLMQFETLIMKVAGRSGVWYYGSYGCFCGAGGQGRPQDASDRCCFVHDCCYGKVNGCDPKKDFYTYSEENGDIVCGGDDPCKKEICECDKDAAICFRDNKDTYDNKYWFFPAKNCQEESEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that has high lipolytic activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 4, svPLA2, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 isozyme IV, PLA2-IV.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMC_PASMU
Sequence: MISLESQVLQRHLSFFEHKSVLFAGGINDQFPQQVPARSVKVWSWYFDYAKSKSAVDFSLTCEEKADLMVFYWTKNKQEVQFQLMQLLAQAPIGQEMLIVGENRCGVRSVEKMLDAYGDIAKIDSARRCGLYHFCLKNTPHFALADYWKTYQHPRLGDLRIYSLPGVFSANELDVGTDLLLSTLDQPVRGKVLDLGCGAGVIGAYIKQQYPQVELTMADIHALALASSQRTLAENQLEAEVIASDVFSNVAGKFDLIISNPPFHDGIDTAYRAVSELIMQAKWHLVPGGELRIVANAFLPYPDLLDQHFGSHCVLAKTTKFKVYSVRG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_CORGL
Sequence: MDNHAAVREFDEERATAAIRELLIAVGEDPDREGLLETPARVARAYKETFAGLHEDPTTVLEKTFSEGHEELVLVREIPIYSMCEHHLVPFFGVAHIGYIPGKSGKVTGLSKLARLADMFAKRPQVQERLTSQIADALVEKLDAQAVAVVIEAEHLCMAMRGIRKPGAVTTTSAVRGGFKNNAASRAEVFSLIRGH
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: COQ7_LEGPA
Sequence: MRTSSFLDRLISEVDSALRTLVLPPKRITTRQSPAENLADTVLSAQEKKHISGLMRVNHAGEVCAQALYQGQALTAQLTHIKEQMASAAAEEVDHLAWCEERLYELGSKPSLLNPIWYCGSVLLGALAGLAGDKVSLGFVAETERQVTAHLQRHLHYLPEKDKKTIAILKRMQEDEEHHAHTAMEAGAVELPYIIKQLMNAVSKLMTQSSYYI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MPPA_NEUCR
Sequence: MLNRFRPARLVAQSSRCLPLTRARAGPLPVNNARTLATRAAAVNTKEPTERDNITTLSNGVRVASEDLPDAFSGVGVYIDAGSRYENDYVRGASHIMDRLAFKSTSTRTADEMLETVEKLGGNIQCASSRESMMYQAATFNKAIPTAVELMAETIRDPKLTDEELEGQIMTAQYEVNEIWSKAELILPELVHMAAFKDNTLGNPLLCPKERLDYINRDVIQTYRDAFYRPERLVVAFAGVPHERAVKLAEKYFGDMKASDAPGLSRTGSETSVDSLVSESSEASSESSSSSSDSSESSGGLLSKLFSPKAKKATPNPFLTRVPISTEDLTRPAHYTGGFLTLPSQPPPLNPNLPTFTHIQLAFEGLAISDDDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTNVLNQHGWVESCVAFNHSYTDSGLFGIAASCYPGRTLPMLQVMCRELHALTTDHGYSALGELEVSRAKNQLRSSLLMNLESRMVELEDLGRQVQVHGRKIPVREMTRRINELTVKDLRRVAKRVVGGMANNAGQGSGAPTVVLQEATVQGLKTTELGWDQIQDTIAQWKLGRR
What is the function of this protein?
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
What are the official names of this protein?
Mitochondrial-processing peptidase subunit alpha, Alpha-MPP, Inactive zinc metalloprotease alpha, Matrix processing peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TGL11_ORYSJ
Sequence: MGEARRGQNPHHVLGYGFHGTTLPNSMASANLFEQGGGGGGGAAYFGELEEALVHQVATLRRRAQQTATTTTSHHGHTTPFSTAAAAATATATARPPATLDIFPSWPMRRSSLPTPKDGCSNVTADTTDSESSSKNNGDQGAAAADMASQFDQIPQQQQKQHKKMAASSTHSDHRMTKTLDPKIMRRLAQNREAARKSRLRKKAYIQQLESSKLRLAQMEQDLERARSQGLLLGGSPGGNTSAGAAMFDAEYGRWLEDGGRRMAELHGGLHAHLPDGDLRAIVDDALAHYDELFRLRAAAAKADVFHLITGTWATPAERCFLWMGGFQPSDLLKTVAPQLDPLTEQQVVGICSLQQSSQQAEEALSQGLEQLHQSLAETVANGGSVVNEASLGSFMGYMALALGKLSNLEGFVIQADNLRQQTLHQMHRILTIRQAARCFLAIGEYHNRLRALSSLWASRPREILVADEGNCGELSIAAQPSESQFSAF
What is the function of this protein?
Transcriptional regulator involved in defense response.
What are the official names of this protein?
Transcription factor TGAL11, bZIP transcription factor 83, OsbZIP83.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPB_STRCO
Sequence: MDAELTNRSRDAINAASNRAVTEGNADLTPAHLLLALLQGQDNENITDLLAAVEADLAAVRTGAERIVAGLPSVTGSTVAPPQPSREMLAVVADAQARAKELGDEYLSTEHLLLGIAAKGGAAGEVLEGQGASAKKLQEAFRKARGGRRVTTADPEGQYKALEKFGTDLTAAARDGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKDKRLVALDLGAMVAGAKYRGEFEERLKTVLAEIKDSDGQVVTFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDEYRERIEKDPALERRFQQVLVAEPTVEDSIAILRGLKGRYEAHHKVQIADSALVAAASLSDRYITSRFLPDKAIDLVDEAASRLRMEIDSSPVEIDELQRSVDRLKMEELAIGKETDAASLERLERLRRDLADKEEELRGLTARWEKEKQSLNRVGELKEKLDELRGQAERAQRDGDFDTASKLLYGEIPDLERDLEAASEAEEEVARDTMVKEEVGADDIADVVASWTGIPAGRLLEGETQKLLRMEDELGKRLIGQTQAVRAVSDAVRRSRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYSEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYTVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILVLTSNLGSQYLVDPTTGEAEKKQQVLEVVRSSFKPEFLNRLDDLVVFSALSQEELSRIARLQINGLARRLAERRLTLEVTDEALAWLAEEGNDPAYGARPLRRLVQTAIGDRLAREILSGEIKDGDTVRVDRFGDELIVGPASGKTL
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_STAAB
Sequence: MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVVSGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTNGKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKPHIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLYFSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIIDSLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFDELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSPACASWDQYSTFEERGEKFIERFRAHLPSY
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.