PharMolix/UniProtQA huggingface dataset:
Protein: EFG_ACTP2
Sequence: MARTTPISRYRNIGISAHIDAGKTTTSERILFYTGVSHKLGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMSKQFEQHRINVIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYQVPRIAFVNKMDRTGANFLRVVDQIKTRLGGNSVALQLPIGSEDNFKGVVDLIKMKAINWNEADQGMTFTYEDIPADMLEACEERRAMLVEAAAEASEELMEKFFSGEELTEEEIKTALRQRVLANEIIPVCCGSAFKNKGVQAMLDAVIEYLPAPTDIPAIKGINEDETEGERHASDDEPFAALAFKIATDPFVGNLTFFRVYSGVINSGDTVYNSVKQKRERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVGTGDTLCAQDAPIILERMEFPEPVISVAVEPKTKADQEKMGLALGRLAQEDPSFRVHTDEESGETIISGMGELHLDIIVDRMRREFKVEANIGKPQVSYRETIRTTVKDVEGKHAKQSGGRGQYGHVVIDLYPLEPEGPGYEFVNEIKGGVIPGEFIPAVDKGIQEQLKSGPLAGYPVVDVGVRLHFGSYHDVDSSELAFKLAASLAFKSAFGRANPVLLEPIMKVEVETPPDYVGDVIGDLSRRRAMVNGQEANEFVVKINAEVPLSEMFGYATDLRSQTQGRASYSMEPLKYAEAPTSVANAIIEARKAK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM5_COLGU
Sequence: MASGILVNIKEEVTCPICLELLTEPLSLHCGHSFCQACITANHKKSMLYKEGERSCPVCRISYQPENIRPNRHVANIVEKLREVKLSPEEGQKVDHCARHGEKLLLFCQEDRKVICWLCERSQEHRGHHTFLMEEVAQEYHVKLQTALEMLRQKQQEAEKLEADIREEKASWKIQIDYDKTNVLADFEQLREILDWEESNELQNLEKEEEDILKSLTKSETEMVQQTQYMRELVSDLEHRLQGSVMELLQGVDGIIKRIEDMTLKKPKTFPKNQRRVFRAPDLKGMLDMFRELTDVRRYWVDVTLAPNNISHAVIAEDKRRVSSPNPQIMYRAQGTLFQSLKNFIYCTGVLGSQSITSGKHYWEVDVSKKSAWILGVCAGFQPDAMYNIEQNENYQPKYGYWVIGLQEGVKYSVFQDGSSHTPFAPFIVPLSVIICPDRVGVFVDYEACTVSFFNITNHGFLIYKFSQCSFSKPVFPYLNPRKCTVPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2.
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: URE2_RHIL3
Sequence: MIPGEIIAASGDIELNAGAPTVTLEVSNTGDRPVQVGSHYHFAETNAGLSFDRAVARGKRLDIPAGTAVRFEPGQTRSVTLIPLSGKREVYGFRQLVMGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB6_BIGNA
Sequence: MAVIYNWFNDRLEIQAVADDITAKYVPPHVNLFYCLGGITLTCFLIQVATGFALTFYYRPTVGEALSSVRSIMLDTNFGWLIRSVHRWCASMMVLMMVLHVFRVYLTGGFKNPRESTWVTGVIMASCTVSFGVTGYSLPWDQVGYWAVKIVTGVPEAIPVIGPAIVQLLRGNSSVGQATLTRFYSLHTFVLPLLTAVFMLGHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RLMH_DELAS
Sequence: MKLLIVAVGQHVPDWAQTAYDDYAKRFPPELKVELKAVKTEPRGSKTVETLYAAERKRIEAAIPRGTRIVVLDERGTNLTTKALAQRLQGWQLEGDDVALIIGGPDGLDPAFRQAAHERIRLSDLTLPHAMVRVLLIEQLYRAWSVNAGHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DABA_XANOR
Sequence: MLMTTTTIAMSLSHDVIIAAAQRAARAIPPLWPLASSVAVNPFLGQASEPLEVAAARLRRASGIAVTMPRSWYAERLQSGEITEDDLQAAFQTAPAARRPPNVSALKHAIKVARPAPQAIPTVAELARDVTAIDWPGIVNERIGHWAAGYFDQGQALWAVGQSGGAYSTWRIIATHDLTPEIAGLAGFSQSVSDAPATAEDALVDCVARLGLSPDALDGYFHRLLTTLGGWGQVARYRLWQAELNGGTDACVTDLLAIRMLWEAALLHNGGSALVPGWQSAIAAYAAPVAASSDDVVDSILQEAAERAAQRKLNTVLAAPSSARLSRGRLTLQMAFCIDVRSEVFRRALESLDSGITTLGFAGFFGFGIGHRRFASDVVEARLPVLLSPGVVTCAGEPTPAANAAELSARITARAKRAWGRFKLAAISSFAFVEATGPIYIAKLLRDGLALARHHAPTDPAPRPAHELDLDTRLTMAARILKAMSFTSNFARLVVLAGHGAKVVNNPHASALHCGACGGYSGEVNAQLLASLLNDHQVRAGLAERGIVIPADTLFLAALHDTTTDAVTLFADDHPSPTHAQDLAQVTQWLAAAGALARGERALRLPRANRSQDIAHRARDWAEIRPEWALAGCQAFIAAPRSRSAGRDLAGRAFLHDYDWRCDHGFGVLELILTAPVVVASWISLQYYGSTVAPERFGAGNKLLHNVTGGIGVVEGNGGILRTGLPWQSVHDGERLIHEPLRLSVLIEAPTEAIGAILERHPQLRALFDNRWLHLFALDDEGRMARRYIGDLSWETYVGDASSQSNRASTLA
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MUTS2_SYNY3
Sequence: MSDSTNLTIAEETLALLEWPRLCQHLSTFTQTPLGAIAARYLLPPSQWEESRELLAQTQAVESIENSPESNWHFKGIADITEPLARVERGGLVTGLELLAIAGTLAGVRRLRRVIEERDDLEILQTLVAEVRTLPELEQAIHHCLGEDGKVAERASPKLGEIRQKLKAVREQIQQKLQKIIQRQSNALQEAVITQRGDRFVLPIKAGYKEQMPGIVHDSSASGNTLYVEPQAIVELGNKLRQARRQEQTEEERILRQLSDQVLEVLLDLEHLLAIATRLDLATARVRYSFWLGAHPPQWLTPGDEKPITLRQLRHPLLHWQAEKEGGPAVVPITLTIDSQIRVIAITGPNTGGKTVTLKTLGLVALMAKVGLYIPAKETVEMPWFAQILADIGDEQSLQQNLSTFSGHICRIIRILQALPSGVQDVLDPEIDSPNHPIFPSLVLLDEVGAGTDPTEGSALAIALLRHLADQPCLTVATTHYGELKALKYQDARFENASVEFDDQSLSPTYRLLWGIPGRSNALAIAQRLGLPLAIVEQAKDKLGGFSEDINQVIAGLESQRREQEQKAANAQKLLQETEIFYQQVSQKAASLQARERELKSYQDQEVQQAIAAAKEEIAKVIRQLQRGKPSAQKAQQATEILGQIQAEQKAKVAPKPIGYQPTVGERIRIPSFGQTAEVTQVNATAQTVNVTLGLMKMTVPMADIESLNGKKVEPPPKSEPVPKKVKAEPPATEAKSPPVLVRTEKNTLDCRGDRLERAESRLEKALNQALDAGVLWIIHGKGTGKLRQGVQEYLSHHPLVKSYALAPQNDGGAGVTIAYLR
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: RL30_FRATT
Sequence: MTQAKTFKVTLVKSLIGRKENHIASARGLGLRKINHTVEVLDTPENRGMANKIYYMVKIEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: NS1_HBOC2
Sequence: MAFSAPVIRAFSQPAFTYVVKFPYENWKEEEHLLWSLLAPGTERLMIQLRNCAPHPEDDPVREDILCSLADQHYGAIFAKACYIATTTLMGQKQRTPFPRCDIICQSEIGSEHLHCHILVGGAGLSKRNAKISRATLLGLVMAELTQRCKQLLALRPFEPAEANIFHLLKRIEREAWSGHTGNWVQILQYKDKRGDLHAQPIDPLRFLKHYILPKNRLISPSSKPDVCTTPDNWFILADKTYAHTIINGLPLLEHNRKAYLQELESEVIPGPSTMAFGGRGAWEQLPEVGEQRLITSNASTAYKANKKEKLMLNLLDKCDELNLLVYEDLVSACPDLLLMLEGQPGGARLIEQVLGMHHIKVCAKYTALTFLFHLHPDQLLTSNNKALKLLLIQGYNPLQVGHAICCVLNKQMGKQNTICFYGPASTGKTNFAKAIVQGVRLYGCVNHLNKGFVFNDCRQRLIIWWEECLMHQDWVEPAKCILGGTECRIDVKHKDSVLLQQTPVIISTNHDIYSVVGGNTVSHVHAAPLKERVLQLNFMKQLPQTFGEISPVEIAELLQWCFNEYECTLTGFKQKWNLDKVPNSFPLGDLCPTHSQDYTLHENGFCTDCGGYLPHSADDFVYTDVASETTSGDCDPGNLGDTDGEDSKSEASEVDFRPSKKRRVISATPPSSPVSGPSLSTFLDTWQSQPRDEDELRIYEEQASQLQKNTKSTPEREEAQLGEPQEPQPEPDPTAWGEKLGVCSSQQPGEPPVVLYCFEDLRPSDEDEGENIGGE
What is the function of this protein?
Multifunctional protein which displays endonuclease and helicase activities required for initiating and directing viral DNA replication.  Also plays a role in viral packaging and transactivation of several promoters.  Binds site-specifically to 2-3 approximate tandem copies within the origins of replication (Ori), unwinds this hairpin region and nicks one DNA strand thereby initiating the rolling circle replication (RCR).  Becomes covalently attached to the 5' end of the nick and provides a 3'OH for priming DNA synthesis.  The helicase activity unwinds DNA in a 3'-5' direction on the longer strand.  Participates in the transcriptional regulation of several promoters.
What are the official names of this protein?
Initiator protein NS1, NS1, Non-structural protein 1, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the parvoviruses initiator protein NS1 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CHDC_STAAW
Sequence: MSQAAETLDGWYSLHLFYAVDWASLRLVPKDERDALVTEFQSFLENTATVRSSKSGDQAIYNITGQKADLLLWFLRPEMKSLNHIENEFNKLRIADFLIPTYSYVSVIELSNYLAGKSDEDPYENPHIKARLYPELPHSDYICFYPMNKRRNETYNWYMLTMEERQKLMYDHGMIGRKYAGKIKQFITGSVGFDDFEWGVTLFSDDVLQFKKIVYEMRFDETTARYGEFGSFFVGHLINTNEFDQFFAIS
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: MTNB_CROSK
Sequence: MAACHWIGAKGWAPATGGNMSLREDARWCWLSESGKDKGSLTTDDFLQVEIATNLAPSGRKPSAETGLHTLIYRLFPEANCVLHVHTVNATVLSRVEKSDALHLSGYEMQKSLAGQITHLDDVPVAIFDNDQDIDALAERIARHHRQFPLRYGFLLRGHGLTCWGSDVAVARRHLEGLEFLFECEMQRRLLERA
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: LEUD_ACTTI
Sequence: MDKFVTHLGKIMPLRRSDVDTDQIIPAVYLKRVTRTGFEDGLFSAWREDPGFVLHNPAHAGATILVAGPNFGTGSSRQHAVWALRDWGFKVVI
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: GPDA_FRATW
Sequence: MQKNILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHKYLPSIEKFPSRLKAIQDWQANIIEFDSILVATPSSGFKNTILELKECILPQQNIISATKGFCHDSYALLSEIAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINYARYVQELFSNENFRCYTTTDIIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGANSETFIGLSCLGDLLLTCSDNQSRNRRFGLYLGQGMTIQQALKEVNNVVEGYFTAKAVYNLAKKHNVEMPLVFATYRILYEAADPRDIVKELMTRQLKNEN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_NANEQ
Sequence: MRYGGVDEAGRGPIIGPMVIALVIGDSGYLKELGVKDSKLLTKEQREELFNEIVKNSLVKYEIVSPSLIDRYNLNELEAKVTANLINSIEDEISHIVIDSPERPENYKLRILKYLKKRVKIITKNKGEEDPLVAAASIVAKVIRDREIEKIKEQTGIDFGSGYPSDKRTRKALEQYYRILKPYIRKKWPFEINKKLTDFI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_PROMM
Sequence: MAKRVQVVLNEDVLSLGKDGDLVEVAPGYARNFLLPFGKAVPVTPAVMKQVGHRRAKQAEHQAAIKQEALDFQTALVTIGRFTVKKQTGEDDVLFGTVTNGDVAEAIETATKKEIDRRNIIVPEIHRTGSYKVQVKLHNEVNAEINLEVVSY
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DPOD3_MOUSE
Sequence: MAEQLYLENIDEFVTDQNKIVTYKWLSYTLGVHVNQAKQMLYEYVERKRKENSGAQLHVTYLVSGSLIQNGHSCHKVAVVREDKLEAVKSKLAVTASIHVYSIQKAMLKDSGPLFNTDYDILKSNLQNCSKFSAIQCAAAVPRAPAESPSSRKYEQSNLQAASEAQASELTTNGHGPPASKQASQQPKGIMGMLISKAATKTQDTNKETKPEAREVTSASSAGGKAPGKGSVMSNFFGKAAMNKLKVNLDSEQAVKEEKTVEQPPVSVTEPKLAAPPAQKKSSRKSEPGKVQQKEKSSRGKRVDLSDEEAKETEHLKKKRRRIKLPQSDSSEDEVFEDSPEMYEADSPSPPPVSPPPDPMPKTEPPPVKRSSGETKRRRKRVLKSKTFVDEEGCIVTEKVYESESCTDSEEELKMKPASAHKPPAAAVKREPREERKGPKKGAAALGKANRQVSITGFFQKK
What is the function of this protein?
Accessory component of both the DNA polymerase delta complex and the DNA polymerase zeta complex (By similarity).  As a component of the trimeric and tetrameric DNA polymerase delta complexes (Pol-delta3 and Pol-delta4, respectively), plays a role in high fidelity genome replication, including in lagging strand synthesis, and repair (PubMed:10219083, PubMed:27524497).  Required for optimal Pol-delta activity.  Stabilizes the Pol-delta complex and plays a major role in Pol-delta stimulation by PCNA.  Pol-delta3 and Pol-delta4 are characterized by the absence or the presence of POLD4.  They exhibit differences in catalytic activity.  Most notably, Pol-delta3 shows higher proofreading activity than Pol-delta4.  Although both Pol-delta3 and Pol-delta4 process Okazaki fragments in vitro, Pol-delta3 may also be better suited to fulfill this task, exhibiting near-absence of strand displacement activity compared to Pol-delta4 and stalling on encounter with the 5'-blocking oligonucleotides.  Pol-delta3 idling process may avoid the formation of a gap, while maintaining a nick that can be readily ligated.  Along with DNA polymerase kappa, DNA polymerase delta carries out approximately half of nucleotide excision repair (NER) synthesis following UV irradiation.  In this context, POLD3, along with PCNA and RFC1-replication factor C complex, is required to recruit POLD1, the catalytic subunit of the polymerase delta complex, to DNA damage sites.  Under conditions of DNA replication stress, required for the repair of broken replication forks through break-induced replication (BIR).  Involved in the translesion synthesis (TLS) of templates carrying O6-methylguanine or abasic sites performed by Pol-delta4, independently of DNA polymerase zeta (REV3L) or eta (POLH).  Facilitates abasic site bypass by DNA polymerase delta by promoting extension from the nucleotide inserted opposite the lesion.  Also involved in TLS, as a component of the tetrametric DNA polymerase zeta complex.  Along with POLD2, dramatically increases the efficiency and processivity of DNA synthesis of the DNA polymerase zeta complex compared to the minimal zeta complex, consisting of only REV3L and REV7 (By similarity).
What are the official names of this protein?
DNA polymerase delta subunit 3, DNA polymerase delta subunit p66.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Partially colocalizes with PCNA and POLD1 at S phase replication sites. Recruited to DNA damage sites within 2 hours following UV irradiation.
Protein: GPDA_RICRO
Sequence: MNKFKNIAVYGGGSFGTSLASLAAQNCNNVTLFLRDEAIAKEILHNKTNVKYLGDIKLPAHLQATTNLDIIKDFELIIIAVPSYAFDDSIKLLKTHSISKDNTLLIATKGFARNPTTLFSDRLKTLLPHSPTAFFVGPNLAKELAKNLPASASIASLDIDIANKIAYNLSSKIFTTNVSSDIVTLQVAGALKNIFAIKSGIDLARKQGENARATLIVAALKEIAILSKALGGMQKNSDILLEGVVGDLVLTCYSLGSRNTKFGYELGISSDKKQFLQEYKELVEGREALKLVLDLIKKYNLHMPIISEVASCVIPYVIPAKAGMTYESTQQCLRRNDI
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBP1_RABIT
Sequence: EQLIELVGPWKTVYIVHFNGET
What is the function of this protein?
Binds the chemical odorant, 2-isobutyl-3-methoxypyrazine.
What are the official names of this protein?
Odorant-binding protein 1, Odorant-binding protein I, OBP-I.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
Protein: PURA1_TRYCC
Sequence: MDKQAERGQSAGPVKTPQGTQPPAHNYTYHTNAAQRAVYDYLKNVKPIPELAEPKTYKTYEEASVEAVLYPIIEKHQVIMVAGAFFGDEGKGKTVNAVANHPGCTFIARVNSGENAGHTVYDDAGRKFVFNLAPSGLLSKGKRNYVGPECVMDPISFMENEVKQLIEANVPYKEQLFIGNVSIVTPYHKLLDLLASAPNSSTLKGMAPIHASKVTKRGIRLDHIFNDQSVLRSRLRKDIDTYFGFLKVKGLSDADVLRRCEKENGDGVVRVPPYVVEFVQAEDKVEYLVKLYMDRVRNNKNFPARCDVAHELRSALSRGEKVMLEGPQSYWLSNAREKFWESTTSADTTASGLLATAQYNFQLYSSVVINVHKAPGSSRVGVGANPSSFVAQDYFSATGVKTLRDLPENMCVDFDSIQKLFFTKAFHPETKEYNGIWEPLEFEDSTGKYNIGVAMAVASSRQHGECGAVTKKPRVCGFFDCVLQYEVNAVQGPYLSISALDRGDDYDKLGVTIAYVYYNGKNDEVLNINGREYKNGDIIKAGEAVPGEVALYYCHPIVKLINGWKQTPIAASKRKPGDPLPRGVCEFLSTVEYFTKAKIISIGNGPRGKDIIYIKQ
What is the function of this protein?
Plays an important role in the salvage pathway for purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase 1, AMPSase 1, AdSS 1, IMP--aspartate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_RHIME
Sequence: MKINACNWLLTLAVVFAATLTSAYAASRIKDVASLQSGRDNQLIGYGLVVGLQGTGDSLRSSPFTDQSIRAMLQNLGISTQGGDSRTRNVAAVLVTATLPPFASPGSRLDVTVGSLGDATSLRGGTLVMTSLSGADGQIYAVAQGSVVVSGFNAQGEAAQLSQGVTTAGRVPNGAIIERELPSKFKDGFNLVLQLRNPDFSTAVGMAAAINRYAAAQFGGRIAEALDSQSVLVQKPKMADLARLMADVENLVIETDAPARVVINERTGTIVIGQDVRVAEVAVSYGTLTVQVSETPTIVQPEPFSRGETAYEPNTTIEAQADGGTVAILNGSSLRSLVAGLNSIGVKPDGIIAILQSIKSAGALQAELVLQ
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: RAPA_DICDI
Sequence: MPLREFKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDSNQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSIISNSTFNELPDLREQILRVKDCEDVPMVLVGNKCDLHDQRVISTEQGEELARKFGDCYFLEASAKNKVNVEQIFYNLIRQINRKNPVGPPSKAKSKCALL
What is the function of this protein?
G protein of the Ras family that positively regulates phagocytosis and negatively regulates macropinocytosis (PubMed:9950684).  May be involved in the activation of guanylyl cyclase during the response to hyperosmotic conditions (PubMed:12186953).  Overexpressing cells generate alterations in cell shape and contractile responses (PubMed:12186953).  Involved in chemotaxis via regulation of the balance of Ras and Rap signaling at the leading edge of chemotaxing cells (PubMed:27237792).
What are the official names of this protein?
Ras-related protein rapA, Ras-related protein rap-1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: IL4_BUBBU
Sequence: MGLTYQLIPVLVCLLVCTSHLVHGHKCDITLAEIIKTLNILTTRKNSCMELPVADVFAAPKNTTEKETFCRVGIELRRIYRSHTCLNKFLGGLDRNLNSLVSKTCSVNEAKTGTSTLKDLLERLKTIMKEKYSKC
What is the function of this protein?
Participates in at least several B-cell activation processes as well as of other cell types.  It is a costimulator of DNA-synthesis.  It induces the expression of class II MHC molecules on resting B-cells.  It enhances both secretion and cell surface expression of IgE and IgG1.  It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.  Positively regulates IL31RA expression in macrophages.  Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
What are the official names of this protein?
Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROK_THEYD
Sequence: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA2_STAEQ
Sequence: MAQEVIKIRGGQALKGEVEISGAKNSAVAIIPATLLAQGQVKLEGLPQISDVETLVSLLEDLNIEARLNGKQLEVDTTQIENAPLPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSNTSMKLVAKELRGAHIFLDMVSVGATINIMLAAVHAKGQTVIDNAAKEPEVVDVANFLMSMGADIRGAGTTSIKINGVEELKGSEYQIIPDRIEAGSYMCMAAAMGEEVILHNIVPKHVEALTVKLQELGVDIEIEDEKIIIRKQTPYKNVDIKTLVYPGFATDLQQPITPLLFMTEGPSFVTDTIYPARFKHVEELQRMGANIKSDEGTAVIKPSTLNGAEVYASDLRAGACLITAGLIAEGVTTIFNVKHIYRGYTNIVEHLKALGADIWTETV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.