PharMolix/UniProtQA huggingface dataset:
Protein: SYI_THENN
Sequence: MDYKNTLNLPKTSFPMRANLVNKEKAFLKEWEEMDLYNYVLEQRKGKPLFVLHDGPPYANGHIHIGTALNKILKDIVVKYKTMRGYRAPYVPGWDTHGLPIEHRVSQELGDRIKEMSPAEIRKKCEEFALKFVEIQKEEFKRLGVRGDWNNPYITLKPDYEVKILDVFKTLVEQGNVYRSLKPIYWCPRCRTALAEAEIEYHDHRSPSIYVKFRSKDDPNLYIVIWTTTPWTLPANVGIALHPDFEYSVVKVGDERWVIATDLLETFSRETGVDCSEVVEKIRGKDLEGKEFQHPIFEDKTSRVILADYVSLETGTGCVHIAPGHGEEDYVYGHVKYGLPIVSPVDEEGRFTDEAGKYRGMFIEDSNRVIIEDLKEKGILVHASTITHSYPHCWRCKGPVIFRATEQWFISVDHNNLRQRVLEEIDRVKWIPEWGRNRIRSMVEERPDWCISRQRVWGTPIPAVKCKECGEVTLDPKVIEHFMKIVEKEGTNAWFEKDVEELIPDDFRCPKCGARSFEKMLDTLDVWIDSGSSFEYITTREDHPFPLDMYLEGSDQHRGWFHSSIFLAVAKRGSAPYKEVLTHGFIKDELGRKMSKSLGNVVDPMEVVEKYGAEILRLWLASSDYFNDIKISMRIVEQQTEVYKKIRNTFRFLLGNLEDFDPELDRVPYEKLLTIDKWALGRLQEIIKRATEYYDSYEFSKVYNLVVKYCTTELSSLYLDVVKDRLYVEAKDSLYRRSAQTVMHEILIALMKILAPIMTFTMEEVYSHLHEKDRKYKTVQAEYWPEYREDLIDKKIMEDFEKLLSIREDVLKALEEKRQQDVIGHSLDAEVILVPRNDSVKALLEEYRDVLEELFIVSKVSLSDGSGELKGELVEVTAKHAEGEKCQRCWKYTTEISRSEEFPAVCPRCLAVLKGERK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_CITBB
Sequence: MRRQMKITAVIPARYASTRFEGKALADIMGRPMVQHVYERAAKATLVSEVIVATDDERIAAAVRAFGGRVEMTSPTHETGTDRLAEVAARIDADIIVNVQGDEPLIDPAMIDEAIRPLLDDPSIPMATLKCRIKTLHDFLSPNVVKVVSDPTGNVLYFSRSPLPFFRDKWNDLKDDAFVSGKLLCYKHVGLYVYRREFLPVFAGLQPTYLELAEKLEQLRVLENGYRIKIVETEFESIGVDTPADLDKVLERLKG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KV04_RABIT
Sequence: ADIVMTQTPASVSEPVGGTVTIKCQTSQSIDDYLSWYQQKPGQPPKGLIYRASTLASGVPSRFRGSGSGTDFTLTISDLECADAATYYCQSTYGVGFGGGTEVVVKG
What are the official names of this protein?
Ig kappa chain V region 4135.
Protein: RECX_HAEIG
Sequence: MSSLAFNYIVNLLSHREYSEFELRNKMQEKNFSEEEIDEALSRCQAKNWQSDRRFSENYLNSRAQKGYGVGRIRQELRQLKGVSSDIIDEVLMESEIDWYEMAENLLRKKFPNYNEQQTPKMKQKIWQYMLSHGFRSDEFADLIGQNQSEWD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_SALRD
Sequence: MENLAWSPFKSLTAEQREQIDRFREQLLRFNQRVNLISPETEDTFRTRHLLHCLTLTARDFPAGCTVVDWGTGGGLPAIPLAICHPEATVVGVDSVGKKSRAVRTIARRLGLDNCFTWNGRADEWTGEAHYSVSRATAPLADLWAWHRRVAVSPDDPNGDAWPPGLLALKGGDLSDEVAALHAADPDARVERHSLNDLLGRNGFFGEKEIVAVRS
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP58_VANPO
Sequence: MAYVLTETSAGYALLKASDKKIYKSSSLIQDLDSSDKVLKEFKIAAFSKFNSAANALEEANSIIEGKVSPQLQKLLEEAKKDKKSTLVVSETKLANAINKLGLNFNVVSDAVTLDIYRAVKEYLPDLLPGLNDTDLSKMSLGLAHSIGRHKLKFSADKVDVMIIQAIALLDDLDKELNTYAMRCKEWYGWHFPELAKIVTDSVAYARIILAMGVRSKCADTDLSEILPEEVEERVKTAAEVSMGTEITETDLDNIKALADQIVDFAAYREQLSNYLSSRMKAIAPNLTQLVGELVGARLIAHSGSLISLAKSPASTIQILGAEKALFRALKTKHDTPKYGLLYHASLVGQATGKNKGKIARVLAAKAAVSLRYDALAEDRDDSGDIGLEARAKVENRLSQLEGRDLRTTPKVVREAKKVEITEARAYNADADTAAVEESASDSDDEEEEEDKKKEKKEKKDKKDKKDKKDKKDKKRKRDEEDEEKKESKKSKKDKKEKKEKKDKKDKKSKKEKK
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HDFR_YERPE
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPAGERLVPYAEMLLNTWRLAKKEVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRLEARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGHFSLRLYSSFSLDLPKEDDTPNEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEHWQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GUAB1_MYCBO
Sequence: MMRFLDGHPPGYDLTYNDVFIVPNRSEVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPIPAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVILEGRPIGLVRESSCLGVDRFTRVRDIAVTDYVTAPAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGVDVLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGADNPFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW
What is the function of this protein?
Involved in the purine-salvage pathway.  Catalyzes the NADPH-dependent conversion of GMP to IMP.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate reductase, GMPR.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
Protein: MRAY_XANP2
Sequence: MLQWLAEFHASFPAFNVFRYITFRTGGAVVTALLFVFLFGPGMISTLRLKQGKGQPIRTDGPQSHLLTKKGTPTMGGLMILSGIVVATLLWANLSNPYVWVVLGVTLGFGLIGFYDDYLKVTKQTHNGLSGKARLAIEAVIAGVAVVIVMSVGKPGLSTSVAFPFFKDLLLNLGMFFAIFGMFVIVAAGNAVNLTDGLDGLAIVPVMIAAGSFGFIAYLAGNVVFADYLQIHYVAGVGELAVICGALMGAGLGFLWFNAPPAQVFMGDTGSLALGGLLGTVAVATKHEIVLAVIGGLFVLEAVSVIVQVVSFKLTGKRVFKMAPIHHHFEQLGWTEPQVVIRFWIVAVVLALAGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEF1_STRCO
Sequence: MGTPSDRVPLAERVEELLAVGGPLPIVAAGDPVLRRAAEPYDGQVAPALFERFVEALRLTMHAAPGVGLAAPQVGVGLRVAVIEDPAPVPDEVRVARGRVPQPFRVLVNPSYEPAGAGRAAFFEGCLSVPGWQAVVARHAEVRLRAHDEHGRAVDEVFAGWPARIVQHETDHLDGTLYLDRAELRSLASNAAMAELWSQPTPRRAASALGFELPGPAA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: S6OS1_HUMAN
Sequence: MNDSLFVSLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSVENDSDEVEERAENFPRTSEIPIFLGTPKAVKAPESLEKIKFPKTPPFEINRNRNAVPEVQTEKESPGLSFLMSYTSRSPGLNLFDSSVFDTEISSDQFNEHYSARNLNPLSSEQEIGNLLEKPEGEDGFTFSFPSDTSTHTFGAGKDDFSFPFSFGQGQNSIPSSSLKGFSSSSQNTTQFTFF
What is the function of this protein?
Meiotic protein that localizes to the central element of the synaptonemal complex and is required for chromosome synapsis during meiotic recombination.  Required for the appropriate processing of intermediate recombination nodules before crossover formation.
What are the official names of this protein?
Protein SIX6OS1, Six6 opposite strand transcript 1.
What are the subcellular locations of this protein?
Chromosome. Note=Component of the central element of the synaptonemal complex. In spermatocytes, detected from zygonema to pachynema and localizes along synapsed lateral elements. Loading to the central element of the synaptonemal complex is dependent on the assembly of the tripartite synaptonemal complex structure that occurs upon synapsis between homologous chromosomes.
Protein: PTHP_STAAC
Sequence: MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_MARMS
Sequence: MVKAKWRSVDGIVLLNKPIGLSSNQALQRVRRLYQAAKAGHTGALDPLATGMLPLCLGEATKFSQYLLDADKRYLTCIQLGKRTTTGDREGEVLTEDSVPTLTDESLEEILNGFRGEIEQIPPMYSALKHEGKPLYEYARQGIVIERKRRRVTISNLTLVSRTEDTLTLDIQCSKGTYIRTIGEDIGEALGCGAHLHSLHRISTAGYLPENMMTLEEFEAIAEQGYDALDAHLITMDTAVEHFAKVELPESDTVNMMFGRTVPSPVSLEHEAVVRMYDQGTQRFLGLGQIKGAFIRPYRLVNTSEFSL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ARGA_EDWI9
Sequence: MKERSTELVQGFRHSVPYINAHRGKTFVIMLSGEAIAEANFVGIINDIALLHSLGIRLVVVYGARPQIDTLLREQRCDPRYHKQIRITDARTLALVKQAAGQVQLDITARLSMSLSNTPLAGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEAALRCQLDAGAIVLLGPVAVSVTGESFNLTTEEIATHLAIKLQAEKLIGFCAAQGVCSDDGSIAAELLPNEAEQRVSALEAAGKAAQASTRFLRGAITACRSGVGRSHLISYLEDGALLQELFSRDGIGTQIVMESAEQIRRANINDIGGILALIRPLEQQGILVRRSREQLEREIERFTLIERDSLTIACAALYPFPQERMGEMACVAVHPDYRNSARGEQLLQRITAQARQMGLEKLFVLTTRSLHWFQERGFQPVEVDMLPQQKQALYNYQRRSKILLTEL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLB_OPHHA
Sequence: GLCCPMRWSSSEG
What is the function of this protein?
Binds to the platelet and collagen receptor glycoprotein VI (GP6) and activates platelet aggregation.
What are the official names of this protein?
Snaclec ophioluxin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG_SYNSC
Sequence: MSDLKCPFSGHTGAVTASAHTGNRQWWPIQIDLGLLHQHHPASNPLGDTFDYPAAFAGLDLEALKADLAALMTDSQDWWPADWGHYGGLFIRMAWHSAGTYRGADGRGGAGHGNQRFAPLNSWPDNTNLDKARRLLWPLKRKYGNAISWADLIILSGNVALESMGFRTFGFAGGRTDIWQPEEDVFWGKETEWLSDERHTTEGALDQPLAAVEMGLVYVNPEGPHGHPDPVASGPDVRDTFARMGMTMEETVALVAGGHTFGKCHGAAPVSQLEAEPEGAELHQQGLGWHNRFESGKGEHTITSGIEGAWKPHPTRWDQGYFEMMFTYEWELTKSPAGAWQWVAKDVKPEHMIPDAHVPGRASAPIMTTADLSLRHDPLMEPVARRFHQDQDAFADAFARAWFKLTHRDLGPRALYLGADVPEEIQIWQDPVPALDHPLIGAVEIKALKQKLLATGCSVGALVATAWGAASTFRGSDRRGGANGGRIRFQPQNTWEVNDPEQLRSVLQTLETVQQQFNAEATGGQRVSMADLIVLAGSAAVEQAAAAGGHSVTVPFLPGRMDASADQTDTASFNLLKPIADGFRNWQRSGLPLRAEECLVDRAQQLGLSAPEMTVLLAGLRVLGANNGGNRQGVLTDRVGVLSNDFCVNLLDMSIRWSPTSEAMEGYIGRDAQGSERWTASRADLVFGSNSQLRAIVEVYAQDDGASRFVSDFVQAWVKVMNLDRFDVR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: FAK1_XENLA
Sequence: MAAAYLDPNLNHNPSTNAKSRLSTGMERSPGAIERVLRVFHYFESNNEPATWSSNIRHGDATDVRGIIQKIVDSHKVKNVASYGLRLSHLHSEEVHWLHPDIGVSHIREKYEQSHPPEEWKYELRIRYLPKGFVNQFTEDKPTLNFFYQQVKNDYMSEIADQVDQEIALKLGCLEIRRSYGEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRYDKECFKCALGSSWIISVELAIGPEEGISYLTDKGSNPTHLADFTQVQTIQYSSSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVSGASESFIIRPQKEGERALPSIPKLANNEKHGVRPHAVSVSDEFSGDETDDYAEIIDEEDTYTMPSKSYGLDEAGDYEIQRDRIELGRCIGEGQFGDVHQGVYMSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYSYQLSTALAYLESKRFVHRDIAARNVLVSSSDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKLQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFFPSPQHMMQPNHYQVSGFSVAHGIPSMSGNMYPGQASVLDHMDSWNHRTPDINMWQPSMEDSGPMDMRSLAQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSVDHVDGNIQCPAGNQHIYQPVGKPDHVAPPKKPPRPGAPSHLGNLPAHNSPVDGYNEGVKPWRIQPQEISPPPTANLDRTNDKVYENVTGLVKAVIEMSSRIQPAPPEEYVPMVKGVGLALRTLLATVDETIPVLPASTHREIEMAQKLLNSDLAELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKIISHSRPH
What is the function of this protein?
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis.  Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy.  Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly (By similarity).
What are the official names of this protein?
Focal adhesion kinase 1, FADK 1, Protein-tyrosine kinase 2, pp125FAK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium basal body. Note=Constituent of focal adhesions.
Protein: RAPA2_RHIL3
Sequence: MASPIHATDDSATFQETDVISGNLLSNDSSDNGHLFLRAFDGASVGAKSGNSQVTEIQGDYGTFFVKPDGSYTYVLSDAAKIGFANGESFQEKVSYKISDGSGHTDVGLFTLNIQGVTQVKPIAVDDHYSFNEGDAIGGNVLDNDIAGDNGHLFLRQFDGTNVSAKSGPDAVTDIVGDYGVFHVKPNGEFTYELTDDLAAGQTVTETVQYYKISDGEGHTDAGVLTLNITGTDALV
What is the function of this protein?
Interacts specifically in a calcium-dependent manner with the acidic exopolysaccharide (EPS) and capsular polysaccharide produced by R. leguminosarum.  Could be involved in the development of the biofilm matrix made of EPS.
What are the official names of this protein?
Calcium-binding lectin RapA2.
What are the subcellular locations of this protein?
Secreted. Note=Secreted by the type I secretion system PrsDE.
Protein: DNAJ_LISMC
Sequence: MAKRDYYEVLGVSKSASADEIKKAYRKLSKQYHPDINKEAGADEKFKEISEAYEALSDPQKRAQYDQYGHVDPNQGFGGGAGGGFSGGGFSGFEDIFDTFFGGGGRQQDPNAPRQGSDLQYTMRLKFKEAIFGKDAEIEIPREENCDTCHGSGAKPGTTPEKCSHCGGKGSINVEQNTPFGRVVNKRTCQYCNGTGKEIKEKCPTCHGKGRVTKTKKIKVKVPAGVNDGQQMRVSGEGEAGINGGPNGDLYVVFVVIPDEFFEREADDIYVEVPITFVQATLGDEIDVPTVHGKVRLKIPSGTQTGTTFRLRGKGVPHLRGNGTGDQHVIVKVIVPKKLDDKQKEILREFASTTGDKVDEQTSGFFDKMKRAFKGD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSQ_RICTY
Sequence: MRQKTSSNKKKQKNTNNISLRRKLGLMYKKAILGLKIVLMIFVCLFVFTKYFTSIKTYLITNIYQITTKLGFRLENVIIEGQQNVDELTILKVLNANKRSSIFALKLDEISNNLKKSKWIKEVYVSRRLPNTVYIKLFEREPIAIWQINNQLFLVDEEGYKISKDIQPFSHLLHVVGEGANIYASQLVLELKKYPALLNKTLVAIRVGDRRWDLNLKGNISIKLPEKEFEAALKYIDALNKNNRLFNQNYKALDLRDRNKYYIQKY
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: SYI_LATSS
Sequence: MRIKETLNLGKTAFPMRAGLPNREIDWQKGWADNNLYQQRQKLNEGKPSFVLHDGPPFANGNIHMGHALNKTSKDIIVRYKSMNGFRAPFVPGWDTHGLPIEQALAKKGIKRKEMSLVDYRKLCYDYAMEQVNTQRQDFKRLGISADWDNPYITLTADFEAEEIRVFGEMAKKGYIYKGKKPVYWSPSSESTLAEAEIEYKDIKSPSMYVAFNVVDGKDLLDADTKFIIWTTTPWTIPANLGIAVNPAFDYVQVLADGQKYVVAAERLNKMTDLLGWESVEILKTFKGADMELMTARHPLYDRESLVILGNHVTLETGTGLVHTAPGHGEDDYNAGTKYKLPVLSVVDSKGIMTEDAPGFEGVYYDKANPMVTEALEKNGSLLKLDFFTHSYPHDWRTKKPVIFRATAQWFASIDAFRDQILAQIEKVEFMPEWGKTRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTEIITPETIERVAQLFAEHGSNVWFEWDAKDLLPAGFTHPGSPNGEFTKEKDIMDVWFDSGSSHQAVLAARDELTYPADLILEGSDQYRGWFNSSLITSVAVGEVSPYKAVISQGFVLDGNGRKMSKSLGNTILPEKIIKQMGADIVRLWVASVDASSDVKVTMENFQQVSEAYRKIRNTMRFMIANTTDFDPAKDTVDYAELGSVDKFMLVRLNAIIESCKAAYDAYDFATVYKTINMFLTNELSAFYLDFAKDVVYIDGQNDAPRRNMQTVFYAVAVALTKLLTPILPHTAEEIWSYLHEPEEFVQLAEMPEVAHFAGEEDLVATWNAFMGIRDDVLKALETARMDKVIGKSLEAAVTLYPNEANAALLASLDADVKQLLIVSQLTIADQAVEAPAEATQFDGVAVSVAHAEGDVCDRCRMIKTDVGSDDKFPMLCARCAAIVTANYPEAVAEGLEK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_PSEA8
Sequence: MRDKVTGARRWVVKIGSALLTADGRGLDRNAMAVWVEQMVALHCAGIELVLVSSGAVAAGMSRLGWVSRPSAMHELQAAASVGQMGLVQAWESSFALHGLQTAQVLLTHDDLSDRKRYLNARSTLRTLVELGVVPVINENDTVVTDEIRFGDNDTLAALVANLVEADLLVILTDRDGMFDADPRNNPDAQLIYEARADDPQLDAVAGGSAGALGRGGMQTKLRAARLAARSGGHTVIVGGRIERVLDRLRAGERLGTLLTPDRSRKAARKQWLAGHLQMRGTLVLDDGAVKAVSQDHKSLLPVGVKAVQGSFRRGEMVVCVDQGGREVARGLVNYSALEAQKILGQPTDAIEALLGYVDGPELVHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGH_PSEE4
Sequence: MSNSSARPESLSEYLAHLPLSDEQRAELARCTSFSELHQHLAAQPAASTTEAAQASVGPRLTVGSAAELEEAEMLGVDASGRLCLKIAPPIKRTKVVPEPWRTNVLIRMWRRMTGRTNAPQPPKRELPPARWRTVGSIRRYILLTLMIGQTLVAGWYMKGILPYQGWSFVDFDEIVHQPLWDTVVQVWPYALQTSILVLFGILFCWVSAGFWTALMGFLELLTGRDKYKISGSSAGNEPIAPEARTALVMPICNEDVPRVFAGLRATFESVAASGNLDRFDFFVLSDTNDTDIAVAEQQAWLDVCREAKGFGRIFYRRRRRRVKRKSGNLDDFCRRWGGEYKYMVVLDADSVMSGECLSSLVRLMEANPDAGIIQTGPKASGMDTLYARLQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRMKPFIEHCALAPLPGKGAFAGAILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFLFLVLSTALLATNTLMEPQYFIEPFQLYPLWPQWHPEKAIALFSTTIVLLFLPKLLSVILIWAKGATEFGGRVKVTLSMLLEMLFSMLLAPVRMIFHTRFVLAAFLGWAATWNSPQRDDDSTPWSEAVRRHGPQTLLGIAWASLVAWLNPSFLWWLAPIVGSLVLSIPVSVISSRVRLGLAARDEKLFLIPEEYATPPELLATDQYTHENRWHALHDGFVRAVVDPRQNALACAMATARHGQAAPIEALRAERVAKALEVGPKGLDGNTRLALLSDPVALSRLHEQVWAEHNTAWIDVWRASIDNDPHSPLLPLHPENVAQPALA
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACDH_ECOLI
Sequence: MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIASKSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA
What is the function of this protein?
Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A.  Is the final enzyme in the meta-cleavage pathway for the degradation of 3-phenylpropanoate.  Functions as a chaperone protein for folding of MhpE.
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: ISPH_SYNY3
Sequence: MGVMNTEYQSHLIQEIRQNNYRLERGDVTILLAEAFGFCWGVERAVAMAYETRQHFPGDRLWITNEIIHNPSVNQRLREMEVNFIDVVNGEKDFSGVAKGDVVILPAFGASVEEMQLLNDRECTIVDTTCPWVSKVWNSVEKHKKKEHTSIIHGKYNHEETIATSSFAGTYLIVLNMAEAQKVCDYILHGGDRQEFLDYFANAHSAGFDPDQDLVRLGVANQTTMLKSETEMIGKLFEKTLLQKYGPIELNNHFMSFNTICDATQERQDAMFDLVEEDLSLMVVIGGFNSSNTTHLQEIAVEHGIPSVHIDSGDRIGPGNRVEHKPLGKDLEVLEPWLPAGKITVGVTSGASTPDKVVEEVMKKILAIKEAQPVLEIAG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.