PharMolix/UniProtQA huggingface dataset:
Protein: RS8_MYCS5
Sequence: MFLTDPISDLIVRIKNANQRKHKTVEIPHSNKKEAIVKLIKEEGYISSYSVEGSKKTDKRLLVTLKYKGKQSAIVGIKRVSKPGLRVYVKSEEIPKVLSGYGTCIMSTSKGLMTDKEARKANVGGEIIAFIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y4243_AGRVS
Sequence: MDQRMNGVDPKMLELLVCPLTNGRLTLNRENNELVSEKARLAYPIRDGIPIMLVSEARKIED
What are the official names of this protein?
UPF0434 protein Avi_4243.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: CYNS_ECO8A
Sequence: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: PGP_ARCFU
Sequence: MFKPKAIAVDIDGTLTDRKRALNCRAVEALRKVKIPVILATGNISCFARAAAKLIGVSDVVICENGGVVRFEYDGEDIVLGDKEKCVEAVRVLEKHYEVELLDFEYRKSEVCMRRSFDINEARKLIEGMGVKLVDSGFAYHIMDADVSKGKALKFVAERLGISSAEFAVIGDSENDIDMFRVAGFGIAVANADERLKEYADLVTPSPDGEGVVEALQFLGLLR
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: RL14_CARRP
Sequence: MIQEQTYLKVADNSGGKIVKCIKVLNGTNKKYANIGEIIKVVVKTANFKSKIKKSQVLKAMIIRSKTGIKRLDGTIIKFNDNSVILLNNNEQIISTRVFGIILRELKNEKFAKLISLSNEII
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CBLC_MOUSE
Sequence: MAAAAAPRGWQRGEPRALSRAVKLLQRLEEQCRDPRMVTGPPSLRDLLPRTAQLLGEVAKARREAREDPEGPGGADDFLAIYLANLEVKGRQVAELLPPRGKKDVNQDVFREGSRFRRQLAKLALIFSHMHAELSALFPAGKYCGHLYQLTKGSAHIFWRQNCGVRCVLPWAEFQSLLCACHPVEPGPTMQALRSTLDLTCNGHVSVFEFDVFTRLFQPWPTLLRNWQLLAVNHPGYMAFLTYDEVQTRLQAYRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPLNKPLLQVLLKGQKDGIFLFPDGKKHNPDLTELCRVEPYQRIQVSEEQLLLYQAMNSTFQLCKICAERDKDVRIEPCGHLLCSCCLAAWQDSDSQTCPFCRCEIKGREAVSICQAQERPTEVRTAADGSRDNCHQEAAEQKLGPVIPSAPSLLPEDQFPQGPQDKGWLTLAPLALPRLRPPLPLPKMASVLWEVTSRPRAREEATESS
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome.  Functionally coupled with the E2 ubiquitin-protein ligases UB2D1, UB2D2 and UB2D3.  Regulator of EGFR mediated signal transduction; upon EGF activation, ubiquitinates EGFR.  Isoform 1, but not isoform 2, inhibits EGF stimulated MAPK1 activation.  Promotes ubiquitination of SRC phosphorylated at 'Tyr-424', has the highest ubiquitin ligase activity among CBL family proteins.  In collaboration with CD2AP may act as regulatory checkpoint for Ret signaling by modulating the rate of RET degradation after ligand activation; CD2AP converts it from an inhibitor to a promoter of RET degradation; the function limits the potency of GDNF on neuronal survival.
What are the official names of this protein?
E3 ubiquitin-protein ligase CBL-C, RING-type E3 ubiquitin transferase CBL-C, SH3-binding protein CBL-3, SH3-binding protein CBL-C, Signal transduction protein CBL-C.
Protein: Y9327_DICDI
Sequence: MDNLKEKPLSYNINNNNLNNNNNNNNNNNNNNNNINNNINNNNFKYVSFSESLEDIGYQNQYIIDKDEDYYIQEQRYIRQNNQSDDEEDFNNNNYEDSIKISLIQKSFIKNKKNKIIITTIVVLLMIAVSLGLILAWQGVFDQIHNNNNNSKDE
What are the official names of this protein?
Uncharacterized protein DDB_G0277605.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: END4_ECOL6
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVAEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL15_ECO5E
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RPO11_SULAC
Sequence: MEIKVIKEEQNYLELQIDGEEHTIGNLLKGMLLKVPGVKFAAYSLPHPLITSITIKILTDGSISAREALIKAIELAENYANLFIDEVKKI
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_SULDN
Sequence: MDNYEYTELLKNLSKKMSNITGVVEPDKLYKRVAQIDELENSQDFWNDSSNAALVQKDKTQCERKLKKYNLAKNAIDDAKELYEMAKEENDEDLIAECFNGAQHIEDLIRTMEIEVLLSEETDGNNAILSIHPGAGGTESQDWASILLRMYKRFAERRGWSVEVLDYQAGDEAGIKDVSLLISGENAYGYLKVENGIHRLVRISPFDSNAKRHTSFSSVMVSPEVDDDINIVIEDRDIRVDTYRSSGAGGQHVNKTESAIRITHIATGVVVQCQNDRSQHKNRATAMKMLKSRLYELELENQKAEIAGIAKSEIGWGHQIRSYVMQPYQQIKDTRSNIAYSNVSAILDGDIDKMIEDVLISQNRS
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_XYLFM
Sequence: MSSVIRYDWTAEELHALFDLSLPELLYRAASVHRQHFDPAEIQVSTLLSVKTGGCPEDCSYCPQAQRYDTGVTAQKLMDVDAVVAKARQAKLAGASRFCMGAAWRSPKDRDIPKIASMIREVKALGLETCATLGMLNTCQAQALKDAGLDYYNHNVDTSPDFYDSVIHTRQYQDRLDTLAHVRDVGLKTCCGGIVGMGETRQHRVGLLLTLATLPAHPDSVPVNLLVQVAGTPLHGTQTLDPFEFVRMIAVARITMPRSMVRLSAGRESMSDELQLLCFMAGANSIFYGEKLLTTANPETERDQALFQRLGLRPMHLMENVSNQDQHHGNVHADIACKHVV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NDHM_SYNJA
Sequence: MLKCTTRHVHIFAGEVTADNHFVPRDDLLTLDVDPDNELVWNDAALQKVYARFEELVEEYRGRDLTEYNLRRIGSDLEHFIRSLLKQGEIAYNLQGRTPNYSMGFPQIPAEEIVGQYIPKG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit M, NAD(P)H dehydrogenase I subunit M, NDH-1 subunit M, NDH-M.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhM subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SSRP_SHIF8
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ARND_SALTY
Sequence: MTKVGLRIDVDTLRGTREGVPRLLATLHRHGVQASFFFSVGPDNMGRHLWRLIKPRFLWKMLRSNAASLYGWDILLAGTAWPGKNIGNANAGIIRETATYHETGLHAWDHHAWQTHSGHWSIRQLEEDIARGITALEAIIGKPVTCSAAAGWRADGRVVRAKESFNLRYNSDCRGTTLFRPLLMPGQTGTPQIPVTLPTWDEVIGPAVQAQSFNTWIISRMLQDKGTPVYTIHAEVEGIVHQPLFEDLLVRARDAGITFCPLGELLPASPESLPLGQIVRGHIPGREGWLGCQQAASAS
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (Probable).
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: AROA_THET8
Sequence: MDAFRLAPCGPLRGRLRVPGDKSVTHRGLMLLALAEGEGRLFYPLKAGDTLSTARVLQALGAEVREEGPHFLVRGRGLRFQEPEDVLDCGNAGTLMRLLLGLLAGQEGLFAVLTGDASLRRRPMGRVVAPLRAMGARVDGREEGERAPLAVRGAPLRGLRYTLPVPSAQVKSALLLAGLFAEGVTEVEEPTPTRDHTERLFRHFGLPLEVEGRKVRTWRTGPFPAKDLVVPGDFSSAAFFLVAALVTPGSEVVVEGVGLNPTRTGLLTVLKAMGADLEWQVLEGEAGEPVGWVRARHSLLKGVAVDPGLIPLMVDEVPVLAAAAAWAEGETYIPGLSELRVKESDRVRAIAENLRALGVEVEEGPDWLRIRGGGVRPGRVRPFHDHRIAMAFAVAGLPVGVEVEEPHWAEISYPGFFQDLLRLCAAS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_DRIGR
Sequence: MLRDGNEGMFTIPGFSQIQFEGFFRFIDQGLTEELHKFPKIEDTDQEIEFQLFVDTYRLVEPLIKERDAVYESLTYSSELYVPAGLIWKTGRDMQEQTIFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGSIISDWGGRSELEIDRKARIWARVSRKQKISILVPSSAMGSNLREILDNVCYPEIFLSFPNEKEKKKIGSRENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNWRLNLDIPQNNLFLLPRDVLAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLALVRLENVVRGTICGAIRHKLIPTPHNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKSSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGYLGSIESPFYEISQRSKEVQTVYLSPNRDEYYMVAAGNSLALNQGIQEEQVVPARYRQEFLTIAWEQIHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGVSAIAEQDGKIIYTDTDKIVLSGNGDTAISIPLVIYQRSNKNTCMHQKPQVPRGKCLKKGQILADGAATVGGELALGKNVLVSYMPWEGYNFEDAVLISERLVYGDIYTSFHIRKYEIQTHVTSQGPERITNEIPHLEAHLLRNLDINGIVMLGSWIETGDILVGKLTPQTAKESSYAPEDRLLRAILGIQVSTAKETCLKLPIGGRGRVIDVRWIQKGGGSSYNPEMIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFECSLGLAGDLLDRHYRIAPFDERYEQEASRKLVFPELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKSYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHISQEMLTYKSDHIRARQEVLGTTIIGGTIPNPEDAPESFRLLVRELRSLALELNHFLVSEKNFQIHRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KAX9A_MESEU
Sequence: VGCEECPMHCKGKNAVPTCDNGVCNCNA
What is the function of this protein?
Blocks Shaker potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 9.10, Toxin MeuKTx-5.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 09 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS9_SALNS
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS17_GEOKA
Sequence: MSQRNQRKVYVGRVVSDKMDKTITVLVETYKKHPLYGKRVKYSKKYKAHDEHNIAKVGDIVKIMETRPLSATKRFRLVEVIEKAVVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: FMT_DEHMC
Sequence: MNELKIVFMGSPEFALTPLKMLLAEGYDICGVYTQPDRPAGRGRELCPPPVKTLALEHGLAVYQPQSLKKPEEQAFLKELKPDVIVVAAYGLILPQAVLDIPVYGVLNIHPSLLPRYRGATPVAATLLGGDEWAGVSLMKLEAGLDTGPVYSRSMVAIRPEDTTPILADKLAFIGGCMLLELLSQIPSLPEPKVQDNTQASYFGMVTKEMGLINWQTSAVEIERRVRAFFPWPGVFTTFNQKTLKILEAKPRNLGLGLKPSEVRVYEQSRVMVGSASGELEIIRLQLEGKAGCSAADFVRGQRNFDGVNLGV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CRBL2_XENTR
Sequence: MDDSKVSGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCAAMDQGKIPSEIKALLSGEDLKAAPNQVKHRAVKTEQKEKCP
What is the function of this protein?
Probable regulator of creb1 transcriptional activity which is involved in adipose cells differentiation.  May also play a regulatory role in the cell cycle (By similarity).
What are the official names of this protein?
cAMP-responsive element-binding protein-like 2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLIPR_STAAS
Sequence: MKKNITKVIIASTVIATGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERADKLIKEADEKNEHYKGKTVEDLYVIAKKMGKGNTIAVVKIKDGGKNGYYTFDITRPLEEHRKNIPVVKNGEIDSITWY
What is the function of this protein?
May be involved in countering the first line of host defense mechanisms.  Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 (By similarity).
What are the official names of this protein?
FPRL1 inhibitory protein, FLIPr.
What is the protein family that this protein belongs to?
Belongs to the CHIPS/FLIPr family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYY_STRP2
Sequence: MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQGQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIETGISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVITVPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDEIEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKELKQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYVLSDADKLENELTVIRRGKKKYFVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK10_MOUSE
Sequence: MAEVDLESDQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIMLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLFMYDPKKRATSGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPAAAEGQSKRCRP
What is the function of this protein?
Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells).  Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2.  Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling.
What are the official names of this protein?
Cyclin-dependent kinase 10, Cell division protein kinase 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: CETN2_HUMAN
Sequence: MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
What is the function of this protein?
As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.
What are the official names of this protein?
Centrin-2, Caltractin isoform 1.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus envelope. Nucleus, nuclear pore complex. Nucleus.
Protein: PINS_FRAAN
Sequence: MPVHATPAAESQIISMPEWRRTANFKPSVWGDRFANYAEDIITQTQMQEQVEELKQVRKEVFTNAADDSSHQLKPIDEIQRLGVAYHFESEIDQALERIHETYQDIHDGGDLYNVALRFRLLRRHGYNVSCDVFNKFKDTNGDYKKSLVTDLSGMLSFYEAAHLRVHGEKLLEEALVFTTTHLQSASAKSSLLKTQITEAVERLLKTMERLGARRYMSIYQDEASYSENLLKLAKLDFNWQCLHKKELSDIP
What are the official names of this protein?
Putative pinene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: TGT_BACVZ
Sequence: MAEQPIRYEFIKECKQTGARLGRVHTPHGSFETPVFMPVGTLATVKTMSPDELKSMDAGIILSNTYHLWLRPGHDIVKEAGGLHKFMNWDRAILTDSGGFQVFSLSKFRNIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPYPAEYDYMKRSVERTSRWAERCLEAHGRSDEQGLFGIVQGGEYEDLRTQSAKDLVSLDFPGYAIGGLSVGEPKHVMNRVLEFTTPLLPKDKPRYLMGVGSPDALIDGAIRGVDMFDCVLPTRIARNGTVFTNEGRLNMKNAKYERDFRPIDEECSCHTCKNYSRAYIRHLIRCNETFGIRLTTYHNLHFLLHLMEQVRQAIREDRLGDFREEFFERYGYNKPNAKSF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: XTH4_ARATH
Sequence: MTVSSSPWALMALFLMVSSTMVMAIPPRKAIDVPFGRNYVPTWAFDHQKQFNGGSELQLILDKYTGTGFQSKGSYLFGHFSMHIKLPAGDTAGVVTAFYLSSTNNEHDEIDFEFLGNRTGQPAILQTNVFTGGKGNREQRIYLWFDPSKAYHTYSILWNMYQIVFFVDNIPIRTFKNAKDLGVRFPFNQPMKLYSSLWNADDWATRGGLEKTNWANAPFVASYKGFHIDGCQASVEAKYCATQGRMWWDQKEFRDLDAEQWRRLKWVRMKWTIYNYCTDRTRFPVMPAECKRDRDA
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.
What are the official names of this protein?
Xyloglucan endotransglucosylase/hydrolase protein 4, At-XTH4, XTH-4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: RL23_CAUSK
Sequence: MAATARHYDTILSPVITEKATLLSEQNKVVFRVSADASKDEIAAAVEELFKVKVTKVNTLVTKGKTKRFRGIIGRRSDVKKAIVTLAEGQSIDITTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PPNP_GEOSL
Sequence: MSEFTNVTIIREANVYFDGGVVSRTVVFPDGTKKTLGIMQPGEYTFTTGAPEIMEILSGELDLKLPGSDAWNRVGGGESFDVPANSSFTMKVLSLTDYCCSFLG
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.