PharMolix/UniProtQA huggingface dataset:
Protein: CNMT_PAPSO
Sequence: MQLKAKEELLRNMELGLIPDQEIRQLIRVELEKRLQWGYKETHEEQLSQLLDLVHSLKGMKMATEMENLDLKLYEAPMEFLKIQHGSNMKQSAGYYTDESTTLDEAEIAMLDLYMERAQIKDGQSVLDLGCGLGAVALFGANKFKKCQFTGVTSSVEQKDYIEGKCKELKLTNVKVLLADITTYETEERFDRIFAVELIEHMKNYQLLLKKISEWMKDDGLLFVEHVCHKTLAYHYEPVDAEDWYTNYIFPAGTLTLSSASMLLYFQDDVSVVNQWTLSGKHYSRSHEEWLKNMDKNIVEFKEIMRSITKTEKEAIKLLNFWRIFCMCGAELFGYKNGEEWMLTHLLFKKK
What is the function of this protein?
Involved in the biosynthesis of benzylisoquinoline alkaloids.  N-methyltransferase methylating (S)-coclaurine.  4'-O-methylcoclaurine and norlaudanine can also be used as substrates.
What are the official names of this protein?
(S)-coclaurine N-methyltransferase, PsCNMT.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEN4_ARATH
Sequence: MAVQTFPNEIVFFDLETNVPNKAGQHFHILEFGAIIVCPKKLEELESFTTLIQPKDLSVVSIRSSRSDGITRAKVTNAPSFEDVAEKIHGLLNGRIWAGHNIRRFDCVRIKEAFAEIGKAAPEPSGIIDSLGLLSDKFGKRAGNMKMASLAAYFGLGVQKHRSLDDVRMNLEVLKHCATVLFLESTLPNHLEGKWHTSSKIMTRSRRNYQIAQRAMPYSKGSLEKMTQNVKNLLSKAQGNQTLQSLINHSHSLLR
What is the function of this protein?
Probable exonuclease required for enuclation of sieve elements.
What are the official names of this protein?
Protein NEN4, NAC45/NAC86-dependent exonuclease-domain protein 4.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in the nuclei prior to enuclation.
Protein: RS21_ENTFA
Sequence: MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVKRKKKSEAARKRKKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: AT329_ASPTN
Sequence: MSPVKQRLLRIAVSHNRHPSLSEEQFHQWATKEHCARAARIHSRHGIEAYGMLFSPETARTTVQNLNRQLGGRWKIDEHDVTVEFYLHSLDELTSVLEDPEFKALQQEEEPYVSGEDIVATLGWVETYVQDGRVVNVDSEGVPTYPGFGVLADFSSEQVNQK
What is the function of this protein?
Putative oxygenase; part of the gene cluster that mediates the biosynthesis of isoflavipucine (PubMed:21236704).  The PKS part of the PKS-NRPS ATEG_00325 probably assembles a triketide from an acetyl starter and two malonyl-CoA extender units (PubMed:21236704).  The poly-beta-keto intermediate would then be fused to the leucine unit by the NRPS part (PubMed:21236704).  The resulting amide would be liberated from the PKS-NRPS through reductive release of the linear PKS-NRPS product from the enzyme complex (PubMed:21236704).  Further steps in isoflapucine synthesis include a cyclization step, an oxidation step, a hydrolysis step involving a trans-amidation, and an additional oxidation step, leading to flavipucine (PubMed:21236704).  Formation of isoflavipucine from flavipucine requires an unusual rearrangement (PubMed:21236704).  Alternative rearrangement reactions could build up rubrobramide, representing a branching of flavipucine biosynthesis (PubMed:21236704).  The enzymes involved in the post-PKS-NRPS steps have not been identified yet, but the putative oxygenases ATEG_003329 and ATEG_00330 encoded by the cluster could play a role (PubMed:21236704).
What are the official names of this protein?
Putative oxygenase ATEG_00329, Isoflavipucine biosynthesis cluster protein ATEG_00329.
What is the protein family that this protein belongs to?
Belongs to the tpcK family.
Protein: GP15_BPMU
Sequence: MENNVQPYDVAGYAIASALVRLLVKKAIITAEEGKAIFSSSAEILKDAPAMRTSRREKLQLSKIMEDIISSLDPDADGSQKPQTHERQ
What are the official names of this protein?
Uncharacterized protein gp15, Gene product 15, gp15.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: CS2H1_ACITH
Sequence: MSTLKEQLTAHVASYDHWAQRRRYGPDGHNNRSLWVLACMDERLPVDEALGIHVDTPAGGGDAHCFRNAGGIVTDDAIRSAMLTCNFFGTKEIVIVQHTQCGMLSGNANEMEKVLREKGMDTDNITLDPTLPELQLAKGAFAKWIGMMDDVDETCMKTINAFKNHPLIPKDIVVSGWVWEVENRRLRAPTLDKEKRARTDCTPTPYGVKGNQPPRWK
What is the function of this protein?
Catalyzes the conversion of carbon disulfide into hydrogen sulfide and carbon dioxide, with carbonyl sulfide as an intermediate.  Likely plays a key role in sulfur metabolism that allows A. thiooxidans S1p to grow on carbon disulfide as the main carbon and energy source.  Does not show carbonic anhydrase activity (hydration of CO(2) to carbonate).
What are the official names of this protein?
Carbon disulfide hydrolase, CS(2) hydrolase.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family.
Protein: ENT5_ARATH
Sequence: MVARFENQAPENLHGKYQAMVVCCILGIGSLVSWNSLLSVGDYYYQVFPDYHPSRVLTFVYQPFSIGTIVIFAYNESKINTRKRNLIGYIVFTTSIFLLIILDLATKGHGGIGPYIVLCAIVGSFGFADASVRGGMIGDLSLMCPELIQSFVAGLAVAGALTSAFRLITKAAFEKTHDGLRKGAMIFLAISTLVEFLCVLLYAYVFPKLPIVKYYRSKAASEGSKTVYADLAAAGIQNQSVLTADDVSKDKRLNNKELLLENVDYVVNLFLIYVLTLSILPGFLYENTGQHGLGSWYALVLIAMYNWWDLVGRYIPMVKWLNVENRKGLTVAVLTRFLLVPAFYFTAKYGDQGWMILLVSILGLTNGHLTVCILAKAPRGYTGPEKNALGNLLVLFILWGAFVGCALGWLWLIGKKNAF
What is the function of this protein?
May be involved in nucleoside transport.
What are the official names of this protein?
Equilibrative nucleotide transporter 5, AtENT5, Nucleoside transporter ENT5.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Plasma membrane.
Protein: Y438_STAAM
Sequence: MGYSKRFALYISVMILIFAIAGCGKSDETKEGSKEEQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWVISSVMVKQPKGEIMKSRGMYLFLNRNTRTAKGYFIVDETSNDTLKKTEDKEKRYPVKMVNNKIVPIDPINDKGVKKEIENFKFFSQYGDFKELKNYKNGEVSYNSEAPIYSAKYQLKNNDYNVKQLRKRYDISTEKAPKLLLKGTGDLKGSSIGHKDIEFTFVENQEENIFFTDSLEFTSSENY
What are the official names of this protein?
Uncharacterized lipoprotein SAV0438.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ADDB_LISIN
Sequence: MTLQIIAGKAGTGKTTHLMDEVGEKIKKTSKTYIFIVPDQMTFQMETSFLNKQNLAGMLGTQIFSFSRLAWKILQETGGLSKTFLSQTGIEMVIRKAALDQKDKLKIFSRATSKKGFYSELAKLFKEMKQEEISVDELEKSAANLSTSVSSKVHDISLIYQKYEELLAGKFLENEDYLRLLADKIIESDYLNQTEIIIDGFTSFSKQELTVIEKLMQKCDKVTVSLTLNVPEIHKGLEDFSMFKASTEAYFALLEMAKLNKIQVEPEKILLENKRANSDSLAFLANAWGDNKYSSYEGGANDLTIHQANNRRAEMEGVAREIRQLALNGYRYRDIAILTRNIGDYDILCETVMESFDIPIFIDKKRAMAKHPFIEFIRSSIDAILFNWKYEPIFQAVKTEFFFDVAENATIMRRKADILENYVLENGIQNKWKWEKEGDWIYRKIRGLSTNVLPQTDEELATQSVINEMRNLIVEPLSTLENNITKAKTGIEFAMALYHYLEQVKAVEHLESWRQVAEENGYLELAREHEQAWSSISELLDEFVEVLGEEELDVNSFSEIITTGLDALEFSLLPPSLDQVVLADMENAKLLNMKVIFAIGMNDGVMPLRQKDKGILSDQDRDSLRVENSNLKPSAKNNIGEEDLLAYKIMSLPSDKLFLSYPAADEEGKVLSESNYLRKIKGQFKNLNESVYLTDPSLLNDKEQSSYIRSKQATLGLLTSQLQMYKRGYPLSNVWWDAYNSYFEDSKESEAAKQVLSSLYYENKTKPLQETTAKNLFGENIHASVSRMEKFFSCEFQHFAQYGLKLEERAHYKLQAVDMGEIFHGAMEWISAELKRTNRDWGNLTEEECRQMAKLAMTFLAPKIQHEILLSSKRMEYIQYKLLQIITRATTVLNEQAKSSAFRPIGLEVDFGLKGDIPPLKIPLQSDSELLLQGRIDRIDAAEQDDRTFLRIIDYKSSSHDLALTEVYYGLALQMLTYLDIVVTNAQKMIGKTAEPAGVLYFHMHNQYVQAEKELSDEAIARELQKSSKMKGLILSDPVAVSLMDTNLEKGKSSNIIPAEIKQNGELSARSRTATKAEFDKMRRFVRQKYQEAGNKILDGAVSINPYKLKEKTPCQFCGFRSFCGFDPSLASNQYRHLTNEKTETILTKMDIEGGTQ
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: MIAB_LEGPH
Sequence: MVKKLYIKTNGCQMNEYDSSKMAEVLYASHGLVKTDQVEDADVILLNTCSIREKAQEKVFSQLGQWREYKAKNPHVLIGVGGCVASQEGSDIIKRAPFVDIVFGPQTLHRLPALLNERLEKNKSVVDISFPEIEKFDHLPAPRAEGPTAFVSIMEGCSKYCSFCVVPYTRGEEISRPFDDVLAECYQLASQGVREINLLGQNVNDYRGIMDNGDIADLALLIHYIAAIDGIGRIRFTTSHPLAFSENLINAYAEVPELANHLHLPVQSGSDRILSLMKRGYTALEFKSKIRKLRKIRPDIRLSTDIIVGFPGETDKDFQDTMDLVHEIGFDTSFSFIYSPRPGTPAANLPDDTPMEIKKQRLQILQNRLLMNAARYSESMIGSKQKILVTGFSKKSSQQLSGRTECNRVVNFDGPPHLIGQFIDVQISDALPNSLRGRLLEKEMQPA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_LEIXX
Sequence: MVPRRSRQRPASSCRTAKTARREMPYPLPAPDGQEPEAQPVTPSPVFPEIEEDVLAFWDRDGTFHASIDNRDGAPEWVFYDGPPFANGLPHYGHLMTGYAKDVFPRYQTMRGKKVERRFGWDTHGLPAELEAERQLGITDKSQIEEMGLAAFNQAAKDSVLKYTREWQQYVTRQARWVDFDNGYKTLDTTYMESVIWAFKQLHEKGLAYEGYRVLPYCWRDQTPLSNHELRMDDDVYKMRQDQTVTVTFPLTGAKAESLGLTGVRVLAWTTTPWTLPTNLALVVGPDIQYAVVPAGPNGAADAHGRPDDEVLSGEYLLAIDLVGNYAKDLGYGSPEAARAAVTRTIPGRELEGVTYDRLWDYYADAATWGTQNAWQILVDGYVTTEDGTGIVHQAPAYGEDDQRVCEAAGIPVIISVDDGARFLPAVQDVAGLQVFEAGKPLIKLLREEGRLLRQASYEHSYPHCWRCRNPLIYKAVSSWFVRVTDFRDRMVALNQEITWVPENVKDGQFGKWLAGARDWSISRNRYFGSPIPVWKSDDPDYPRVDVYGSLAELERDFGRLPLNAAGEPDLHRPFVDDLTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMPFAQVHYPFENSDWFDSHNPADFIVEYIGQARGWFYLLHALSTALFDRPAFTNVISHGIVLGNDGQKVSKSLRNYPDVNDVFDRDGSDAMRWFLMSSPVLRGGNLVVTEEGVREGVRQVLLPLWNTWYFFSLYANATGYEAKRSTASAAVLDRYLLAKTRDLVEAVTADLDALDSTLASAKLRDFADLLTNWYVRRSRDRFWAGVDGEGAGAEAFDTLYTVLETLTRVAAPLLPLVTERIWKDLTGGRSVHLTDWPDAAELPADDALVAAMDRVRAISSTALSLRKQAGLRVRLPLASLTVVAEGAAALAPFEAILRDELNVKAVCLVEGEHSGVDRALTVKARQLGPRIGKRVQEVIRAAKSGDWSEADGVVTAGGVELEPGEYELAVVISAPTARFENGVYIELDTALTPELEAEGLARDIIRAVQDTRKAAGLGVSDRIALTLAFENGGDARVLGLATEVDIASETLARTVQVAAAAGAFVKTFGAGQFANVGDFTVGITKIEEADE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_TALEU
Sequence: MTNIRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDTDKIPFHPYYTIKDILGALILIMALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILVLALMPFLHTSKQRSMMFRPISQCLFWLLVADLFTLTWIGGQPVEHPFIIIGQLASILYFALILMLMPLASLMENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MDTJ_SALPC
Sequence: MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKEATRATI
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIM_LEPBL
Sequence: MPKHSALERAWPAKEIVEDLLELRKRSPLTHIMTNIVVTNWTANVLLAVGASPAMVIAEEEAGEFVKIANGLLINVGTITSNDAKAMKIAATVAHQTNTPWVLDPVAVGALGFRTETTKKLLDLKPTVIRGNASEILTLAGIAGKGKGVDSTVNSKDALPYAQELSGKTGAVVAVSGEVDYVTNGKETIEIYGGDPIMTKVTGVGCSLGALIASFLGIQKDPLRASASASAVFAIAGSRSAKKSNGPGSFAINFIDQLSQLSIE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: BDNF_TROHA
Sequence: SCMKAAPMKEASIRGQGSLAYPGLRAQGNLETLGGPNDATRGLTSLADTFEHVIEELLDEQQVIQPSKENKDADLYSTRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSTSEWVTAAEKKTAVDMSGATVTVLEKVPVPKGQLKQYFYETKCSLKGYAKEGCRGIDKRYWNSQCRTTQSYVRALTMDNKKRVGWRFIRIDTSC
What is the function of this protein?
Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: YBIX_ECO55
Sequence: MMYHIPGVLSPQDVARFREQLEQAEWVDGRITTGAQGAQVKNNQQVDTRSTLYAALQNEVLNAVNQNALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGESEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: METK_PROM4
Sequence: MSQFVFTSESVTEGHPDKICDQISDAVLDALLTQDPHSRVACEAVVNTGLCLITGEVTSTAEVDFINLVRSVIKEIGYKDAQAGGFDANSCAVLVALDKQSPDIAKGVDTAEDHTDDPFDKIGAGDQGIMFGYACNETPELMPLPISLAHRLARQLAKIRHQGTLKYLLPDGKTQVSVIYENNEPIAIDTIVISTQHTSEIDDLSSEADIRERITKDLWEYVVKPATSDLKLQPNQEKTRFLVNPTGKFVVGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARFVAKSIVAAKLAKRVEVQLSYAIGVANPVSILVEAYGSGKMSNQELTKVVKKHFDLRPGAIIEQFNLKNLPSKRSGRFYRDTAAYGHFGRPDLNLPWEKVDEKAKELIALHN
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPDPF_MOUSE
Sequence: MAAIPSSGSLVATHDYYRRRLGSSSSSSSGGSAEYPGDAVLQSPGLPKADPGHWWASFFFGKSTLPFMTTVLESPERSAESPQVSRSPMTCGLTPETMKQQPVIHSGQTNPRDLS
What is the function of this protein?
Probable regulator of exocrine pancreas development.
What are the official names of this protein?
Pancreatic progenitor cell differentiation and proliferation factor, Exocrine differentiation and proliferation factor.
What is the protein family that this protein belongs to?
Belongs to the PPDPF family.
Protein: NCED1_ORYSJ
Sequence: MQRICPAHCSVTHSLTMKSMRLSYIPPAASAAPQSPSYGRKKNASAAPPSAAASTTVLTSPLVTTTRTPKQTEQEDEQLVAKTKTTRTVIATTNGRAAPSQSRPRRRPAPAAAASAASLPMTFCNALEEVINTFIDPPALRPAVDPRNVLTSNFVPVDELPPTPCPVVRGAIPRCLAGGAYIRNGPNPQHLPRGPHHLFDGDGMLHSLLLPSPASSGDDPVLCSRYVQTYKYLVERDAGAPVLPNVFSGFHGVAGMARGAVVAARVLTGQMNPLEGVGLANTSLAYFAGRLYALGESDLPYAVRVHPDTGEVTTHGRCDFGGRLVMGMTAHPKKDPVTGELFAFRYGPVPPFVTYFRFDPAGNKGADVPIFSVQQPSFLHDFAITERYAIFPEIQIVMKPMDMVVGGGSPVGSDPGKVPRLGVIPRYATDESEMRWFEVPGFNIMHSVNAWEEAGGEELVLVAPNVLSIEHALEHMELVHSCVEKVRINLRTGVVTRTPLAAGNFDFPVINPAFLGRRNRYGYFGVGDPAPKIGGVAKLDFDRAGEGDCTVAQRDFGPGCFAGEPFFVADDVEGNGNEDDGYLVCYVHDEATGENRFVVMDARSPDLEIVAEVQLPGRVPYGFHGLFVTQAELQSQHQ
What is the function of this protein?
Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity.  Catalyzes the first step of abscisic-acid biosynthesis from carotenoids.
What are the official names of this protein?
9-cis-epoxycarotenoid dioxygenase NCED1, chloroplastic, OsNCED1.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSD_ECOHS
Sequence: MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYSFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: YBGS_ECOLI
Sequence: MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQVAPDARENVAPNNVDNNGVNTGSGGTMLHSDGSSMNNDGMTKDEEHKNTMCKDGRCPDINKKVQTGDGINNDVDTKTDGTTQ
What are the official names of this protein?
Uncharacterized protein YbgS.
Protein: GLGA_VIBVY
Sequence: MATNPLSILFVASEVEGLIKSGGLADVAKALPEALVNLQHDARIAIPAYTAIPNVCDDEVILDTHLETWPHTHYQVKKRFLGDNPVYLIACGHYFDRPSMYAENNQAYTDNGERFAFFSAACLDMLPKIGFQPDIVHANDWHTGLVPFLLKHRYGQDPFFAQTKSILSIHNAVFKGVFHYDEMQCLPEFHCRNVPDAAVSSTHMTMLKAGVMNADKINAVSPTYAEELKTELGSHGMAWEFQQRAGDLVGILNGCDYSAWHPDTDSYLPINYKATKQSMVRGKNGCKRALQEQVGLPVKDVAMFGMVCRLTHQKGVHYLLPVLTEFLKLDVQLVLVGTGDPLLAAQLRDVAAQFGEKFVFVEAYNNQLAHLVEAASDFFLMPSEFEPCGLNQIYSMAYGSLPIVRGVGGLKDSVCDYDVNPETATGFVFYEPTAQALLITMQRALLLYAQNLTELRRVQLYAMERDFCWNKAAEQYVELYRSALK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RISB_METJA
Sequence: MVLMVNLGFVIAEFNRDITYMMEKVAEEHAEFLGATVKYKIVVPGVFDMPLAVKKLLEKDDVDAVVTIGCVIEGETEHDEIVVHNAARKIADLALQYDKPVTLGISGPGMTRLQAQERVDYGKRAVEAAVKMVKRLKALEE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TAF5L_MOUSE
Sequence: MKRVRTEQVQVAVSCYLKRRQYVDSEGPLKQGLRLSQTPEEMAANLTVQSESGCANAVSAAPCQAEPQQYEVQFGRLRSFLTDSDSQYSREVMPLLYPLFVYLHLNLVQSGPKSTVESFYSRFHGMFLQNASQKDVIEQLQTTQTIQDILSNFQLRAFLDNKYVVRLQEDSYNYLIRYLQSDNNTALCKVLAVHIHLDVQPAKRTDYQLYASGGSSRTENSSLEPPEVPSPILQNEAALEVLQESIKRVKDGPPSLTTICFYAFYNTEQLLNTAEISSDSKLLAAGFDNSCIKLWSLRSKKLKSEPHHVDTSRIRLACDTLEEEENEEDNTGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDVDISPFSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMDNSVRVWDIRSTCCNTPADGSSGELVGVYTGQMSNVLSVQFMACNLLLVTGITQENQEH
What is the function of this protein?
Functions as a component of the PCAF complex.  The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context.  The PCAF complex could be considered as the human version of the yeast SAGA complex (By similarity).  With TAF6L, acts as an epigenetic regulator essential for somatic reprogramming.  Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state (PubMed:31005419).
What are the official names of this protein?
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L, TAF5L, PCAF-associated factor 65 beta, PAF65-beta.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TAF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASZ1_NOMLE
Sequence: MAAGALRGLPVAGGGESSESEDDGWEIGYLDRTSQKLKGLLPIEEKKEKFKKAMTIGDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSEELILKCVELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLLSFTLNPLEGKLQQLTKEDTICKILTTDSDREKDHIFSSYTAFGDLEVFLHGLGLEHMTDLLKERDITLRHLLTMREDEFTKNGITSKDQQKILAALKELQVEEIQFGELSEETKLEISGDEFLNFLLKLNKQCGHLITAVQNVITELPVNSQKITLEWASPRNFTSVCEELVNNVEDLSEEVCKLKDLIQKLQNERENDPTHIQLREEVSTWNSRILKRTAIAVCGFGFLLFICKLTFQRK
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: YQAE_BACSU
Sequence: MFSENLKKCRKQKKLTQQNMADKLGITRPAYTAYELGSREPDYKTLINISNILDVSLDYLLKGESNEKVFQDEAKKVLNDPETFLAAKDGEVTDEILQAALEIITEQLKERRKSDK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YqaE.
Protein: SSTT_CAMLR
Sequence: MSLFSCAIKRYKEGNLILQICIGIVLGILIGIFSKDLAIFANIFGALFTGALKAIAPILVFILILTTICTKEFNHGSEKIKHIIFLYIFGTFLASLSAVSISFIFPVELVLTDIEKASTTSPAHIGEVFKTLLFQIVDNPIHALSSGNYLSILAWAIGGGFALRHCSNDAKQLFTDINEGVLKIVKFIVKLAPFGIFGLVANSVAQTGAAGLLSYIKLLIILVLTMFFVAFVINALIVFAYTKKNPYPLIFICLKHSAVFAFFTRSSAANIPVNMALCSKLNINNSLYSISIPLGATINMAGAAVTIAILSLAAAHTVGIEINFLQAMLLSVLAAFAACGASGVAGGSLLLIPLACSLFNIDYDIAMQVVAVGFIIGVIQDSVETALNSSTDVLFSAICSDNELNLKI
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.