PharMolix/UniProtQA huggingface dataset:
Protein: DPOLL_ARATH
Sequence: MAAKRGRNRSPSPDPEGMFAGMVVFMVEIGVQRRRLQIWKQKLVQMGAVIEEDRVTKKVTHVLAMNLEALLHKFGKERLSHFTARLMLYQWLEDSLTSGEKANEDLYVLKIDSEEVDKPKKSLPAISGSEDQSSPQKRTRYSPDAGDFKGVESHSNTQGSPDSPTSCSVPSTSASPGEGIAETPTSPQSESTSVYKPPDLNRNITEIFGKLINIYRALGEDRRSFSYYKAIPVIEKFPTRIESVDQLKHLPGIGKAMRDHIQEIVTTGKLSKLEHFETDEKVRTISLFGEVWGVGPATALKLYEKGHRTLEDLKNEDSLTHAQKLGLKYFDDIKTRIPRQEVQEMEQLLQRVGEETLPGVNIVCGGSYRRGKATCGDLDIVVTHPDGQSHKGFLTKFVKRLKEMNFLREDLIFSTHSEEGTDSGVDTYFGLCTYPGQELRRRIDFKVYPRDIYSFGLIAWTGNDVLNRRLRLLAESKGYRLDDTGLFPATHSSSGNRGARGTASLKLSTEKQVFDFLGFPWLEPHERNL
What is the function of this protein?
Repair polymerase involved in base excision repair (BER) and responsible for repair of lesions that give rise to abasic (AP) sites in DNA.  Has both DNA polymerase and terminal transferase activities.  Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity (By similarity).  Involved in the repair of transposon-induced DNA double strand breaks (DSBs) (PubMed:21889425).  Involved in repair of UV-B-mediated DNA damage during seedling development through an excision repair mechanism (PubMed:21227935).  Involved the repair of DSBs induced by high salinity and DNA cross-linking agent.  Functions via the DNA non-homologous end joining (NHEJ) pathway.
What are the official names of this protein?
DNA polymerase lambda, Pol Lambda.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IDI1_BOVIN
Sequence: MPEVSTDDLDERQVQLMAEMCILVDENDRRIGAETKKNCHLNENIERGLLHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNTCCSHPLSNPSELEENDAIGVRRAAQRRLKAELGIPMEEVPPEEINYLTRIHYKAQSDSIWGEHEIDYILLVKKNVTLNPDPNEIKSYCYVTKEELEELIGKAAHGEIKITPWFQIIADTFLFKWWDNLNRLNLFVDHEKIHRM
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase 1, Isopentenyl pyrophosphate isomerase 1, IPP isomerase 1, IPPI1.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MOAB_STAAR
Sequence: MGEHQNVKLNRTVKAAVLTVSDTRNFDTDKGGQCVLQLLQVDNVEVSDAHYTIVKDEKVAITTQVKKWLEEDVDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNDKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
What is the function of this protein?
May be involved in the biosynthesis of molybdopterin.
What are the official names of this protein?
Molybdenum cofactor biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the MoaB/Mog family.
Protein: ACCR4_ARATH
Sequence: MALTISISCFSSYFVSLLLLVLSSFSFVCFSLSTVSISHISNQTLVCALNNHSYLQCSSFPLNSIPFSLTGNLRNRRFSGVVSGNGFVCGLISRLDSNTSTLLCWRFSVDGTNMLHKRIYHGPELEELEAGNFRICGVERVSRRLRCWQPYYLPRPDNYRSIALGDNFFCGLSQPPGMISCEGIAKVPSGDHYIAIAAGSRQACAITVDNDVECWGQTQSLPREKFLALAVGEDRGCGVRWSNGTVVCWGNNNNFSLPQTLKDIHFTSIYAKGPMFCGVATRNYTLICWGNENFKSGVFTPFQGLISQVVMPGPCRRECPYRPLSGSQSLCGNELMICDLKRNDGEFPDTRAQNSKNKTWSRRNIAFLVVGCVGTFSLLLVISFLIFKSHCRCRVHDSGRLDDTRTIDIPKLEKRLCTLASLGNPGQLMEFSIDELALATDGFSVRFHLGIGSFGSVYQGVLSDGRHVAIKRAELTNPTLSGTTMRHRRADKDSAFVNELESMSRLNHKNLVRLLGFYEDTEERILVYEYMKNGSLADHLHNPQFDPLSWQTRLMIALDAARGIQYLHEFIVPPVIHRDIKSSNILLDATWTAKVSDFGLSQMGPTEEDDVSHLSLHAAGTLGYIDPEYYKFQQLTTKSDVYSFGVVLLELLSGHKAIHNNEDENPRNLVEYVVPYILLDEAHRILDQRIPPPTPYEIEAVAHVGYLAAECLMPCSRKRPSMVEVVSKLESALAACLTAPKTETVSRSNTY
What are the official names of this protein?
Serine/threonine-protein kinase-like protein CCR4, CRINKLY 4-related kinase 1, AtCRK1, Protein CRINKLY 4 RELATED 4, AtCCR4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PFA4_CRYNJ
Sequence: MAARNWSRVWVGGTVILISFIAFSSQIFVIWPWYGREISLDLLKLLVPLNLAAFMIFWNYRLCVITSPGSVPEGWRPNIGAMDGMEVKKGTHTPRYCKNCEHYKPPRAHHCRQCKTCWLKLDHHCPWIGNCVGFYNQGHFIRFLLWVDIGTTFHLIIMVRRVLYIAEYYHQEPTLADVLFLVFNFATCVPVWLCVGMFSIYHVYLACGNSTTIEGWEKDKVATLIRRGKIKEVKYPYNIGIYKNIKSVLGPNPFLWLWPQKMQGDGLSFPVNPSAGDHTTQYFWPPQDPSRLPNPPPIPAHASPFVYGNNGFNPNLQPTNSLRARRSSTPHIDEDEHSHERDQYRHYSSGEERDNDSISTSSSPKPYLSDYDHYDEGPMYPGERMTALIPRVRRGSEGWEVAPGGGWNAYSGMMDEEVGWDDEVGYDEAPGEGPYVERPWEMRGRYNVYDTEEESGYAH
What is the function of this protein?
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
What are the official names of this protein?
Palmitoyltransferase PFA4, Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: METN2_LISMF
Sequence: MITLQNVVKEYTSRNNKVLAVDHVDLEIEQGEIFGVVGYSGAGKSTLIRMFNGLELPSAGTVEVDNLLISQIRGSKLRKARQQIGMIFQHFNLLWSRTVAENIAFPLEIAGVRGEKRRFRVNELIRLVGLEGKENAYPSELSGGQKQRVGIARALANNPKVLLCDEATSALDPQTTDEVLELLLDINKRLHLTIIVITHEMHVIRKICNRVAVMENGKVVELGDVLDVFRHPQEKVTQRFVRQVTDSDETEELIHLLLDNYAEGKIVKLLFMSENATQPVISQVAKENDVMLNVLHGNLTQTQNGAYGTLYVQVLGTEDAINASLTQLRQLKVETEVLER
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YQGF_LISMF
Sequence: MRIMGLDVGSKTVGVAISDPLGWTAQGVETIQIDENRKQFGYDRVKELVLEYEVEKVVVGLPKNMNNTIGPRAESSKIYAEVLESRIGLPVVLWDERLTTSAAERTLIEADVSRKKRKEVIDKLAAVMILQSYLDTTN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRR_ECODH
Sequence: MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS
What is the function of this protein?
Regulates transcription of many different genes.  In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription.  In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes (By similarity).
What are the official names of this protein?
Transcriptional regulator LsrR.
What is the protein family that this protein belongs to?
Belongs to the SorC transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLU_DROGR
Sequence: MALEIDAKNATAATGDAGGATGGKAKAKENKTNNNNNAAGEKNLVNGSSSSSAAAAAKKKGKKNRNKSPPQQDAIEAEAGAALSNGHAVNGVGDGDADAADANANVLADKPDKATAAAEEKSATPDDEAAAAVAAGDDADLDALNDIGITVNISSPGTDVLSVQLSSMELVQEIHQLLMDREETCHRTCFSLQLDNVTLDNFAELKTIEPLEQGSTIRVVEEPYTMREARIHVRHVRDLLKNLDPADAYNGIDCTSLTYLNTITQGDLLDKKRTRPDSVDCTPPDYVTPGVREPPLLPLHPNIKNAKGPQALKVLTTSAWNPPPGPRKLHGDLMYLYVVTMEDKRFHISACSKGFYINQSTDDNFNPKPDNPSHLSHSLIDLLSHISPSFRRAFQAIQKRRTMRHAFERVATPYQVYQWSAPQLEHTVDAIRAEDAFSSKLGYEEHIPGQTRDWNEELQTTRELPRKTLPERLLRERAIFKVHGDFVTAATRGAMAVIDGNVLAINPGEDAKMQMFIWNNIFFSLGFDVRDHYKELGGDHAAFVAPRYDLHGVRVYNAVDVEGLYTLGTVVIDYRGYRVTAQSIIPGILEREQEQSVVYGSIDFGKTVLSHPKYLELLRLAGKHLKILPHSVLNERDEPVELCSSVECKGIIGNDGRHYILDLLRTFPPDVNFLKLEDVQMSKDLSEMGFPIEHRHKLCCLRQELLEAFIEDRYVTFIRIAAAHLQRLNAKKQADKDLPEEQSTEKPTEQSAEKDPMEKEQDKEKEKDKEAKPNTSSTETKSAEAMVNAIREAQSNVAVSNEVQAAEVVKRACATVGSLKEKEFDFRFNPDVFSPGIRHIDGPDGGGQSLAKQKRLVQDAAEFLVLKQIPAFIKEHTAHSSPPIDGQSLTESLHSHGINVRYLGKVIKMLGQMPRMDYLHRIAILELIVRATKHIYYTYMQSTEPLHLSAAISHFLNCLLTTGPVNPAVSSEEVHKKQLRNNGGKHNKHNKSSKSQAKPQSSSSSSSSAAASTQNGGNNHNSNNSTAAAAGAASSSSASNNSSADWTLVTPRSLWQQIRKETKAYWNFELDCDSVETAGAKYGFLRISLLRAFCLKVGIQVLLREYNFESKHKPTFGDDDIVNVFPVVKHISPRATDAYNFYTTGQAKIQQGLLKEGYELISEALNLLNNVFGAMHQENGSCLRMLARLSYLLGDAGDALAIQQRAVIMSERVNGIDHPSTILEYTHLSLYSFANGHVGMSLKLLYRARYLLVLICGEDHPEVALIDSNISLILHALGEYELSLRFIEHALKLNRKYFGDKAMHVAVSYHLMARTQSCMGDFRSALSNEKETYSIYKSQMGEKHEKTRESAECLRLLTHEAVALQRKMNDIYSNGKLTSDLPPIHITPPSMGSVLEMLNTINGILFVHISQKDIVKVRSEIEKHLKTNTDENEITDALKTIVAAANNNENATETTKDEGAAAAGAAPGAGETPVQLTNGGGEETTATATATVSS
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Protein clueless, Clustered mitochondria protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_PSEA8
Sequence: MAKRHLTRRQSWRIEKIQEERAARAARRESRAVDELEGGDLGPEQTGQVIAHFGVQVEVESADGQVSRCHLRANLPALVTGDQVVWRAGNQGIGVIVAQLPRRSELCRPDMRGLLKPVAANVDRIVIVFAPRPEPHANLIDRYLIAAEHAGIQPLLLLNKADLVDESNAEGIDALLNVYRTLGYPLIEVSAFNGLAMDELRGALDGHVSVFVGQSGVGKSSLVNALLPGVDTRVGDLSTVTGKGTHTTTTARLFHFPGGGDLIDSPGIREFGLGHVSRDDVEAGFIEFRDLLGHCRFRDCKHDREPGCALLQALEDGRIMPQRMASYRHILASMPETDY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_ECOBW
Sequence: MTTETRFLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UHRF1_MOUSE
Sequence: MWIQVRTMDGKETHTVNSLSRLTKVQELRKKIEEVFHVEPQLQRLFYRGKQMEDGHTLFDYDVRLNDTIQLLVRQSLALPLSTKERDSELSDSDSGYGVGHSESDKSSTHGEGAAEADDKTVWEDTDLGLYKVNEYVDVRDNIFGAWFEAQVVQVQKRALSEDEPCSSSAVKTSEDDIMYHVKYDDYPEHGVDIVKAKNVRARARTVIPWENLEVGQVVMANYNVDYPRKRGFWYDVEICRKRQTRTARELYGNIRLLNDSQLNNCRIMFVDEVLMIELPKERRPLIASPSQPPPALRNTGKSGPSCRFCKDDENKPCRKCACHVCGGREAPEKQLLCDECDMAFHLYCLKPPLTSVPPEPEWYCPSCRTDSSEVVQAGEKLKESKKKAKMASATSSSRRDWGKGMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLEALANKEKSRKRPAKALEQGPSSSKTGKSKQKSTGPTLSSPRASKKSKLEPYTLSEQQANLIKEDKGNAKLWDDVLTSLQDGPYQIFLSKVKEAFQCICCQELVFRPVTTVCQHNVCKDCLDRSFRAQVFSCPACRFELDHSSPTRVNQPLQTILNQLFPGYGSGR
What is the function of this protein?
Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification.  Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation patterns through DNA replication.  In addition to its role in maintenance of DNA methylation, also plays a key role in chromatin modification: through its tudor-like regions and PHD-type zinc fingers, specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3) and unmethylated at 'Arg-2' (H3R2me0), respectively, and recruits chromatin proteins.  Enriched in pericentric heterochromatin where it recruits different chromatin modifiers required for this chromatin replication.  Also localizes to euchromatic regions where it negatively regulates transcription possibly by impacting DNA methylation and histone modifications.  Has E3 ubiquitin-protein ligase activity by mediating the ubiquitination of target proteins such as histone H3 and PML.  It is still unclear how E3 ubiquitin-protein ligase activity is related to its role in chromatin in vivo.  Plays a role in DNA repair by cooperating with UHRF1 to ensure recruitment of FANCD2 to interstrand cross-links (ICLs) leading to FANCD2 activation ().
What are the official names of this protein?
E3 ubiquitin-protein ligase UHRF1, Nuclear protein 95, Nuclear zinc finger protein Np95, RING-type E3 ubiquitin transferase UHRF1, Ubiquitin-like PHD and RING finger domain-containing protein 1, mUhrf1, Ubiquitin-like-containing PHD and RING finger domains protein 1.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to replication foci. Enriched in pericentric heterochromatin. Also localizes to euchromatic regions.
Protein: 5HT1F_PANTR
Sequence: MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCR
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various alkaloids and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 1F, 5-HT-1F, 5-HT1F, Serotonin receptor 1F.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVB_MACCJ
Sequence: MDDRIVDNNLIDHYEVEEELSLRPERLSQYIGQHKIKENLDVFIQAAKLRNEALDHVLLYGPPGLGKTTLANIIAHELDVNIKITSGPSIERPGDLAAILSSLNAGDVLFIDEIHRISRVVEEVLYPAMEDFCLDIVVGKGEEARSIRIDLPPFTLVGATTRAGSLSAPLRDRFGVHLRLDYYDMKDLSHIVSRTADVFEVSIDAQSVQEIALRSRGTPRIANRLLKRVRDFAQVRNNGLIDIEMTTQALNLLQVDRYGLDHIDHKILRAIIERYNGGPVGLDTIAVSIGEERITLEDVYEPYLIQKGLLERTARGRVATIHAYEHLNVPYVNEKRK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HLDE_PECAS
Sequence: MKVTLPDFRQAGVLVVGDVMLDRYWYGPTSRISPEAPVPVVKVDTIEERPGGAANVAMNIAALGAGSRLVGLTGVDDAARALNAKLGEVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGIDPQPIIERIQQALPEIGALVLSDYAKGALAHVQTMIQTAKAAGVPVLIDPKGTDFSRYRGATLLTPNLSEFEAVAGRSKTEEELVERGMQLVADYELSALLITRSEQGMTLLQPGKAPLHLPTLAQEVYDVTGAGDTVIGVLAAALAAGNSLEEACFLANAAAGVVVGKLGTSTVTPIELENAIRGRADTGFGVMTEEQLKHAVELARQRGEKIVMTNGCFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGPTRPVNPLPQRMIVLGALEAVDWVVPFEEDTPQRLIASILPDILVKGGDYQPHEIAGSEEVWANGGEVKVLNFEDGCSTTNIINMIKASTSQS
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: UBIB_SHESW
Sequence: MTLTSIRRGYHVIKTLLQYGLDEVLPPKMTPWYFTLARSSLFWIRNKHKSKPGGERLKLAMQELGPVYIKLGQMLSTRRDLLSDEWAIELAMLQDKVPPFDGVLARKAIEAELKASIESLFDDFDETPLASASISQVHTATLKSNGKAVVLKVLRPNVEAKILADLQLMSQTANLLEYFLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAIKLRNNFLNSDALYVPYVYEEFCYPRLMVMERIYGIPVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARSFDIVVQPQLVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMAEQVGPKAMFKKVSTKLPYWSDKLPEFPELIYDNLKLGRKLLSSQQQMLDKYLKHQQQAHKSNYMLITSAVLLICGTLLFNQDATLWSPYVCLTSGVLMWFIGWRSRPKNRKF
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPDQ_ARCNC
Sequence: MIVVQVSDTHIKSKGKLAYNKVDIHKALYNCILHINNLKPKPDLVIFTGDITDNGTNEEYKLFKETVKLLDVPFYVIPGNHDNAENLKREFEEYDWFEENNHLSLVIEDFPIRIIGLDSSIKGKSYGGLSEERLLWLEKQLNKFPDKKVLLFIHHPPVKIGIEHMDVQNLQIGRERLADLLGKYEQVLALACGHVHRVSTTLWNKIIVLTAASPSHQVALDLRKDAKAEFVMEPPSVQLHYWTEEQGLTTHTSYIGKFEGPYPFYNEKGELID
What is the function of this protein?
Catalyzes the hydrolysis of the 3'-5' phosphodiester bond of glycerophosphodiesters such as glycerophosphorylethanolamine (GPE), a typical phospholipid metabolite.
What are the official names of this protein?
Probable glycerophosphodiester phosphodiesterase GpdQ, GDPD, Glycerophosphoryl diester phosphodiesterase, Glycerophosphodiesterase, Glycerophosphorylethanolamine phosphodiesterase, GPE phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.
Protein: SYFA_CLOPS
Sequence: MQDKLNQIKELALVEIKKAKDSTTIDTIRVKYLGKKGELTTILRGMGSLSKEERPIVGKLANEVREVLEAELEAVTKAVKEAEKQEKLKNEVIDISMPGKKQTIGKKHPLEQTLDEMKKIFVSMGFAIEDGPEVEKDYYNFEALNIPKNHPARSEQDTFYINDNIVLRTQTSPVQARVMEKQQPPIKMISPGKVFRSDAVDATHSPIFYQMEGLVIDKDITFADLKGTLELFAKKMFGDKVKTKFRPHHFPFTEPSAEMDATCFVCNGKGCKVCKGEGWIEILGCGMVHPQVLRNCGIDPEVYSGFAFGFGVDRMVMLKYGIDDIRLLYESDMRFLNQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETFA_ANAPI
Sequence: MAFNSADINSFRDIWVFCEQREGKLINTDFELISEGRKLADERGSKLVGILLGHEVEEIAKELGGYGADKVIVCDHPELKFYTTDAYAKVLCDVVMEEKPEVILIGATNIGRDLGPRCAARLHTGLTADCTHLDIDMNKYVDFLSTSSTLDISSMTFPMEDTNLKMTRPAFGGHLMATIICPRFRPCMSTVRPGVMKKAEFSQEMAQACQVVTRHVNLSDEDLKTKVINIVKETKKIVDLIGAEIIVSVGRGISKDVQGGIALAEKLADAFGNGVVGGSRAVIDSGWLPADHQVGQTGKTVHPKVYVALGISGAIQHKAGMQDSELIIAVNKDETAPIFDCADYGITGDLFKIVPMMIDAIKEGKNA
What is the function of this protein?
Part of the ETF-acryloyl-CoA reductase complex involved in the pathway of L-alanine fermentation.  The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for acryloyl-CoA reductase.
What are the official names of this protein?
Acryloyl-CoA reductase electron transfer subunit beta, Electron transfer flavoprotein large subunit, ETFLS, Electron transfer flavoprotein subunit beta, Beta-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_VESOH
Sequence: MDVSQTIVLALIQGLSEFLPISSSAHLILVPKLTNWTDQGLIFDVVVHMGTLSAVIFYYQAMIRSLFFDFYYSIIKRQIIGQSKLAWGVLLGTIPIGLVGMIFKDFVAVDLRSIEIIAYTTLVFGLLLGFASWFNHKNKNPKSTISWIDVSFVSMMQILALIPGTSRSGITITACMLVGLSRKLSIQFSFLLSIPVITLSLILMLIDLYHQTQLVNVSLLVLGFVISTISAYATIIFVIRLIDMVGMTPFVIYRLILGVFLFFL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYL_AGRVS
Sequence: MSTERYNPRDAEPRWQEKWSEAKIFETDNNDPREKYYVLEMFPYPSGRIHIGHVRNYAMGDVVARYKRARGYNVLHPMGWDAFGMPAENAAMQNKVHPKDWTYQNIASMRAQLKSMGLSLDWSREFATCDVEYYQRQQYLFLDMMEKGLVYRKQSKVNWDPVDQTVLANEQVIDGRGWRSGALVEQRELTQWFFKITDFAQDLLDALDTLDHWPEKVRLMQKNWIGRSEGLAIRWEIAAGTGPQGFTDVQVYTTRPDTLFGASFLAIAADHPLAKALSETSSDIAAFCDECRRAGTSLAALETAEKKGLDTGIKVKHPLDPAWELPVYIANFVLMDYGTGAIFACPSGDQRDLDFARKYGLPVVPVVMPRDGDAASFTVGDTAYDGDGVMINSRFLDGLTTQEAFDVVAGKLTAAQLGNEPVAERRVNFRLRDWGVSRQRYWGCPIPVIHCDDCGVVPVPKQDLPVKLPDDVTFDVPGNPLDRHPTWRNVSCPCCGKAARRETDTMDTFVDSSWYYTRFTAPWEDKPTDPAVANHWLPVDQYIGGIEHAILHLLYSRFFTRAMRETGHVAVSEPFKGLFTQGMVVHETYRLGSGANGQWVAPADIRVEDVDGARRAFLLSSGEEVTIGSVEKMSKSKKNVIDPDDILGSYGADTARFFVLSDSPPDRDVIWSEAGIEGSHRFVQRLWRLVSEAADVLRTSASTPAKDGAGRAVSQAAHKTLQAVGADLDKLAFNKAVARIYELLNTLAAPLTQVASGNADTSFVAAVRNATEILIQIIAPMMPHLAEECWAVLGHSGMVSQADWPVFHAELVAENEVVMPVQINGKKKAELTIGRDADQNAVSQAVLDLDAVKAALQGQTPKKIIVVPQRIVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG161_VACCW
Sequence: MMTPENDEEQTSVFSATVYGDKIQGKNKRKRVIGLCIRISMVISLLSMITMSAFLIVRLNQCMSANEAAITDAAVAVAAASSTHRKVASSTTQYDHKESCNGLYYQGSCYILHSDYQLFSDAKANCTAESSTLPNKSDVLITWLIDYVEDTWGSDGNPITKTTSDYQDSDVSQEVRKYFCVKTMN
What is the function of this protein?
Forms a complex with OPG162 and OPG190 to coordinate the incorporation of OPG164 into wrapped enveloped virion (EV) membranes and, subsequently, the production of actin tails (PubMed:23255618, PubMed:11119600, PubMed:31941777).  Therefore plays an essential role in efficient cell-to-cell spread of viral particles.
What are the official names of this protein?
Protein OPG161.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG161 family.