PharMolix/UniProtQA huggingface dataset:
Protein: THIDN_METJA
Sequence: MVILAIGGYDPTSGAGISADIKTAHTLGVYCPTITTSVIPQNNKMVYEKFDLPEENIKNQFKAVFEEFDIEYVKTGVLTKPAIDTLLKYIDKYDLKVICDPVLASTTKFSFVDEKLMEKYIELFNKSFLITPNKEEYKKIMEFIKNNNLMIRNDLYILATGIDDILMKNFKPIKTFKGFRVDKEVHGTGCVYSTAITAFLSKGYDLEEAIKEAKRFVLSSVIYAKKSKFGYNSNPTYINKEKVIKNLSYAIYLLKKMNFTLIPEVGSNIAESLPFPKDFKDVAALTGRIIKNKLGGFYIVGDIEFGASEHIAKIILSASKFNPEIRACMNIKYDGGLIKLLKDKFAVSSFDRKEEPPNVSTMEWGTKIACEKFGGVPDIIYDRGGEGKEPMIRVLGRDAIEVVKKVEVIQKIYNTLM
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Bifunctional thiamine biosynthesis protein ThiDN.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ThiN family.
Protein: MURC_SALRD
Sequence: MAELRTQPALGRIRQVHMVGIGGIGMSSIAEVLLNRGYDVTGSDLERSDVTERLEAEGATIHEGHAAEQVGTADVVVYSSAVDPDENPETREAERRRISLIPRAEMLGELIRMKFGVGVAGTHGKTTTTSMAGLVVAEGGFDPTVIVGGKVTAFGSNAITGEGDVLVIEADEYDRTFLRLTPSLAVITSIEEDHLDVYEDLAAIQASFTQYANSVPFFGAAILCLDDPNVQAIVGDVERRVVTYGTTRQAEVRGENVRREGMTTRFDVVVRGERLGTIELHVPGMHNVRNALAAVAVGQELEISFERVRDGLGTFTGVRRRFEKKGEVGGITVLDDYAHHPTEIEATLDAAHQGFPDRRVVAVFQPHMYSRTQNFMDEFACSFFNADMLVLTDVYGAREAPIEGVTGGRLAERAEQFGHRAVHYVPEKTDLPGRLQELVGPGDVVLMLGAGDIWRASEAFVELLENDGGTAIERD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEIA_HASHE
Sequence: GECCTDCAQTAAANYC
What are the official names of this protein?
Augerpeptide hhe1a.
What are the subcellular locations of this protein?
Secreted.
Protein: RL6_VIBPA
Sequence: MSRVAKAPVAIPAGVEVKLNGQEITVKGAKGELTRVLNDAVVIAQEENNLTFGPKEGVANAWAQAGTARALVNNMVVGVTEGFTKKLTLKGVGYRAAIKGNAVGLTLGFSHPVEHELPAGIKAECPSQTEIVITGCDKQLVGQVAADIRSYRQPEPYKGKGVRYADENVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: IF2_TREPA
Sequence: MVAKVTAARRVSCADENRTPGDASQATISAAPEDKKQGFPDIREDGVARGVSASCGAVQNAASAQVPGARTPGVIGVPVASKTVEEARGGGAKRVITKRVGGVFVLDDSAARPNRKAGNLASGARLSRFSRSDRQRSDGFSGTQARANAGGVRRGEGRPFARDFSRGSTGGYRPAVRGPARPAGRVGSGPRGPAPLQVGAGKPAQNKRSFRGRKQQTYQYQHKDRLELEEKLLQQKKKNKEKLAAVPRSVEIMESVSVADLAKKMNLKASELIGKLFGMGMMVTMNQSIDADTATILASEYGCEVRIVSLYDETIIESVGDEHAVLRARPPVVTVMGHVDHGKTKTLDAIRSTRVAEGEFGGITQHIGAYAVSTPKGSITFLDTPGHEAFTMMRARGAEITDIVVLIVAADDGVMPQTIEAINHAKASKVPIIVAINKIDRADANPNKVMTRLAELGLAPEEWGGDTMYVSISALQGIGLDLLLDAIMLQAEVMELRANYGCCAEGRIIESRIDHGRGIVASVIVRRGVLRVGDTYVAGVYSGRVRAIFNDQGEKIQEATPSMPVEILGLEGMPNAGDPFQVTDSERIARQISLKRQELRRYENARNVKRITLDKLYESIEKGSVSEFKVIIKGDVQGSVEALKQSLEKLSTDEVQLRVIHSSVGAINDSDVMLAAADSNVTIVGFNVRPTPQAAVLAERERVEIKKYTVIYQAVEEMERAMEGMLKPSLKEVVLGSAEVRKVFKIPKVGSVAGVYVLEGVMKRNAIVHVVRDGIVLHSGKVSSLRREKDDVKEVHSGFECGVGVENYFDFRERDRLECAEMKEVSRKLKDAALSDAARLQG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_NITSB
Sequence: MKNLTNEQKEFLLSTIRDVPDFPKPGIVFKDITTLLNNASAFTMLMEHLEERYKEKNIDFVAGIESRGFIFGAALATRLGIGFVPVRKKGKLPYTTISEKYALEYGVDEIEIHIDAFRGEGKRVLLIDDLIATGGTAQAAAKLIQKTGQELVEACFIINLKFLNGEEKLKKLTNIYSVLEIA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP36_CRYNB
Sequence: MFADLNSLPLSTLAKAQKSLSRKSSSSSSNGRSKEEKLALMKSKLAQMQRSKGKAVAVPDTDSHRFGSRAQESDEESDSGPETTSSTKRGSKHAPAALSTKKQVSRKRQVIEVPKPERRDPRFSSVSAGHANADLHSKSYSFLPDLLRQEFSGLKEAVAAAKKAEKNCPWAEKPMRTAERERLEVQMGQVRTKLVRTEKEAMEREVLAKAKKEEREKRTQGKAAWFMKKGESPKCEKKDLLLKARFETLEKQGGKTAVKKLVEKKRKKLASKEKKSRPFAKGAEGMGRDTKRRRVA
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYRM2_SINFN
Sequence: MDQPAWKNPRTALIVDGSDAARQRRIPNLASVDLNLLVELEALLQYRNITHAAQHVGRSQPAMSRALSRLRDMFNDDLLVRGSSGLVPTPQAEHLAQMLPSVLNAIRELVSCSSGLRDLRSKVTMAMPDHQSLVLLPYLLPRLGERVPHVDIVTEPLLDGALRRLEQGEIDFAIGQIGAAPPGYLRRGLYADRFTCLLRHDHPALEQEWSVGTFAALRHASIASDSNEGLGQVYDGLVRFGLPGPIVVSNVLTAAVVVAMTDLVLMIPNRVATRVATMLPLAIVDPPVELKPYEVALIWHQRCHHDLEHRVLRREIAAAARMGRLDVSQDQRARRQNDS
What is the function of this protein?
Acts in trans to stimulate nod gene expression.
What are the official names of this protein?
HTH-type transcriptional regulator SyrM 2, Symbiotic regulator homolog 2.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PLSY_AQUAE
Sequence: MKALFLVIFAYLLGSITFGEVIAKLKGVDLRNVGSGNVGATNVTRALGKKYGVLVFFLDFLKGFIPALIAVKSFGIDSWVLTFTGLASVLGHMYPVFFGFKGGKGVATALGVVFAVSPSVALFSFLVWLGIFLWKRYVSLASITATISAFLFLFVAGYPVNVLFMAIVIGALIIYRHRENINRLLTGREHRF
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMB_AERHH
Sequence: MPVTQDVFNEDGKFMRKIRSFVRREGRLTKGQEKALEELWPVMGIDFAPEPLDLVALFGREAPVVLEIGFGMGASLVEMAKNAPEKNFIGIEVHSPGVGACLGTAQEAGVTNLRVICHDAVEVLEHMIPNGSLACLQLFFPDPWHKSRHHKRRIVQPAFVQDIRQKLAIGGVFHMATDWENYAEHMLEVMSAAEGYENTSATGNWVPRPDWRPLTKFEQRGHRLGHGVWDLIFKRVN
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ARLY_YERPY
Sequence: MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYX_ACTP7
Sequence: MTTENDLLNRIAELETKVAFQEITLEELNQALIHHQLALDKLQTQMRHFAEKLKGAQVSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: Y049_RICM5
Sequence: MGDKIFHNLSGKTLVATPHVITKGIYHKSLIYMLSHTEEGAIGLIFNRLVNHIDLKSFFKIKNDKITTPVMVPIYLGGPIEHEKGFFLHSSDYNKNLLLDFHNDLAVSSNLEISEDIAFGKGPKNSLFIVGYTAWKPGQLEEELEKNLWLVMDCNKEFIFADNPESKWHNALKHLGIDEIHFSSQIGNA
What are the official names of this protein?
UPF0301 protein RMA_0049.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: KTHY_EHRRG
Sequence: MFITFEGIDGSGKTTQSRLLTEYLSGVYGVDNVILTREPGGTFFNESVRNLLFSTKNLDKLSELLFFIAMRREHFMKVIKPALTQQKIVICDRFIDSTIAYQGYGHGIDCKLIEELNDLVVDIYPNITFVLDSDINQSVARSNKNGYEFLDLEFYARVRDGFRDIVKRNQYRCYLITNVDATKNINEISAIYLKTIKILHAL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RIBB_ECOSM
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADDAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: NDHI_VARMX
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: WGE_DROME
Sequence: MATFNPGASSSAADVLSATTATATFLVPTTAAVSHPGAHTAHLQLDQFGGFSAATATPLQHHHHQQTNSSYTFVQIKREPCQVSEISSNNCHQQQQQHHQHHQHQVQHQGLSSASMTASSKTMSSSTLTTLVKIEAPSPKVSELEKSTGNSVPIGIAVARKRPQEALVPAINTPATLPLQPPLNKDLNCFGIRVADLGATSCGNLYFTGNGDLMTTGTATAEELALSAAGVNRAPSTFWQYPNALPIESVISMSPATVGLQYSREASRGQVVLLPAGPTALDPFQQAAAAAAFVWPSAYIPQAPAPGGHSAAAAAAAASLQPTPNLSSLPNFIFPSMGGHQALSTTPSYASTLQLYLAAAATATGSSTMCQHSNQQTSTTTTNSTINLSLAAGSGVTQSGNAASSLSSSSSLSASSSRFLSLATGQTGIPSLLSLPPPTGLKEEYPMPLALPPLVPLEAARDKEQALNLMRLPTPPTSATMEPSSLGHATPHHLFQSGAMATPTPALLNLSMHGNGGELPAATPLPAVSDEAALNYKLHAPLTPQTPPRLADIPVSGSTQLLPQMQDVNIQTDTPVCSEDESFPGSAKPQDPAAEAFPPPTHVQPLELTKPSEASHTQPTECHTQTEPSDIPSASQEESAEQTPPEPIETMTQATQADQTSPEDLTGLELLSNISTNSKPLVRVKQEPVEHIEQPAPQPQPVNIMPSEPTLPMPPMLEMEPTSEREPLGGLKLLCALAEQRIQEEVVQGSSLFATPSSRTPTPTSLALGTTAATPPIFEAKSCYAFGQSQGSVFPSSTSSFQMPLSSPGFPSMQGIELPTTSAGIVAELTPVKRKKHKHSKSSGSDSRKSARCSKKSKKKRHHSSSRQQFSAPAEEDLDLQDDQLQSELRNALHAVDPSYAQRFGQEVFSIMDNSMRMRLAKITRQYRKKKRKLDEISKHKKKKKCSKQQLELQQQQASQQAVQPSSALQQPQMTLSSVLGTSSPLRDYKFPKFSSSNLQASSFLRFPDKTHSFPPPPSLQQSQPEPNPLPSSSSPSTSSFVRLEPSALDAAVAIAPTTSSTSTSGSPSTKQVASARKQRKMKASTVGAAGEQTAATEAKRRFSAIDRELQLTSEHLYRDETRVLTDMGGLFYAGVMKPLRPPDVYSITLDGERGNKSHVMSREDILKDTILEVAPKSVESVPVGTRLCAYWSQQYRCLYPGRAIDSEQVVDGTASSATNAATTAPDFVSVEFDDGDSGRIRLQNIRMLLSDYPIAEYNDNPLYSVGKQKRSALRGGESGPGGVTQDHLTVPGCEDSHSHHSLGMSSDNTTSLAATMELFTQRSEKKRLKKSLKKMSKAQNGVSPATATNGGADAAALGDGVSAEDAARKHHKHKKRKKHKKHHRKNGSEEQEQQVVQQDYSAAGQEATEAPSTEMSSATSSRVKVEVKVKTEQLEMEEEESASNLMSEISDEAKGDDLVEHNNSKGSSKIAAFLPERQLWGWYGTAYRKAGVKGRARKQFYKTIKRGKETITVGDSAVFLSTGRPDRPYIGRIESMWETTTGNKVVRVAWFYHPEETTGCPKLKFPGALFESPHEDENDVQTISHRCEVLQFGSYFEKFGADSKQYQSIYDNNDTYYLAGHYNPRLQVLKLQDDIPTLEELQDTNTTTTTTETTTED
What is the function of this protein?
Functions in the determination of disk-specific identity, downstream of Hox genes.  Overexpression induces ectopic wings with antero-posterior and dorso-ventral axes in the eye field.  Overexpression is sufficient for ectopic expression of vg in eye disks.
What are the official names of this protein?
Protein winged eye.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Chromatin-associated; colocalizes on polytene chromosomes with Psc.
Protein: KATG_BURP1
Sequence: MSNEAKCPFHQAAGNGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RL25_HYDS0
Sequence: MKRVSIELLEREASTKGDKKSKRKEGLVPVEIYGKGVQNIHAYMRIKDLAAMPHGTTFLIEAKLGNEVLPCLLKDIQYGWLGDNPVHVDLYNISNVTETDVEVPLEFVGTPKGVELGGTLEIHLHSIELKVDPRNIPEKITVDISNVDLGGVLHVKDLNIPANCRLMEDPEEVVLVVAEPEETKEGEEEQAQEAATK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: AROB_SALPA
Sequence: MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLAIGKSEVRGGVSHEVVLSAIADCQQA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_CORA7
Sequence: MAQEVLKDLHKVRNIGIMAHIDAGKTTTTERILYYTGINRKVGETHDGGATTDWMEQEKERGITITSAAVTCFWNNNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQAAKYDVPRVCFVNKMDKLGADFYFTVQTIIDRLGAKPLVMQLPIGAEDDFDGVVDLINMQAITWRGKTEIGTDGTIEEIPADLQEKAEEYREKLLETVAESDEELMEKYFGGEELTIEEIKGAIRKLTVNSEIYPVFCGTAYRNKGVQPLLDAIVDYLPNPLDIGEVNGTSLDGEETLTRKPSVQEPFSALAFKIAVHPFFGKLTYVRVYSGQAIPGENMLNSTKNKKERVGKLFQMHANKENPVEHADAGNIYAFIGLKETTTGDTLCNPDNPIILESMDFPDPVIQVAIEPKTKADQEKLGTAIQKLAEEDPTFTVQLDEESGQTVIGGMGELHLDVLVDRMKREFKVEANIGNPQVAYRETIRKKVESLDYTHKKQTGGSGQFAKVIVTIEPYNPDPEELEEGESATYKFENAVTGGRVPKEYIPSVDAGIQDAMQYGFVAGFPLVNIKATLEDGAYHDVDSSEMAFKLAGSQVLKEAVAKAKPVLLEPIMAVEVVTPEEYMGTVNGDISSRRGQVFAMEDRSGAKVVKAKVPLSEMFGYIGDLRSSTAGRANFTMVFDSYAEVPSSVAQEIIEERTGSKA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_STRR6
Sequence: MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSLTYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLGNFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KRE1_CANAL
Sequence: MNVNSVIYYILFLFASTILAADKTSSSVSPTLVWVTGTDANGKLATTQSTYYQSFMSTYTTAETPSSGSIGLGSISGTVGEIRTYSMTTISQGNGGLSKFNQNGLEMKNLSFVKLIGVSFIAFISFILLI
What is the function of this protein?
Involved in cell wall 1,6-beta-glucan assembly possibly by the addition of linear side chains of 1,6-linked Glc units to a highly branched 1,6- and 1,3-linked glucan backbone.
What are the official names of this protein?
Protein KRE1.
What is the protein family that this protein belongs to?
Belongs to the KRE1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted, cell wall.
Protein: THIG_CAMJ8
Sequence: MQENLKNDKLKIGKYEFDSRFILGSGKYSLELIKSAIEEAKTQIITLALRRANTGEIANILDYIPKNITLLPNTSGARNADEALRIARLSRELGCGELIKIEVISDSRYLLPDNYETIKACELLAKEGFTPLPYMHADLYAARAMRDAGAAAIMPLAAPIGSNKGLCAKEFIQILLNEIDLPIIVDAGIGSPSQACEAMQMGVSAVMVNTAIAEAKDVALMAKAFSLAVNAGRAAFLAGLASVSKAKASSPLTGFLRD
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBT32_PANPA
Sequence: MSLPPIRLPSPYGXDRLVQLAARLRPALCDTXITVGSQEFPAHSLVLAGVSQQLGRRGQWXXGEGISPSTFAQLLNFVYGESVELQPGELRPLQEAARALGVQSLEEACWRARGDRAKKPDPGLKKHQEEPEKPSRNPERELGDPGEKQKPEQVSRTGGREQEMLHKHSPPRGSPEMAGATQEAQQEQTRSKEKHLQAPVGQRGADGKHGVLMWLRENPGGSEESLRKLPGPLPPAGSLQTSVTPRPSWAEAPWLVGGQPALWSILLMPPRYGIPFYHSTPTTGAWQEVWREHRIPLSLNAPKGLWSQNQLASSSPTPGSLPQGPAQLSPGEMEESDQGHTGALATCAGHEDKAGCPPRPHPPPAPPARSRPYACSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCSLCGAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSRPSRPSTSPCCPSSSTT
What is the function of this protein?
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence.  May function as a transcriptional transactivator and transcriptional repressor.  Probably exerts its repressor effect by preventing GATA3 from binding to DNA.  May play a role in regulating the differentiation and activation of helper T-cells (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 32.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Located in nuclear speckles.
Protein: CH60_CLOBM
Sequence: MAKSLLFGEQARRSMEAGVDKLADTVRVTLGPKGRNVVLDKKFGSPLITNDGVTIAREIELEDPYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVTAGANPIQIRTGIRKAVEKAVEEIKVISKPVNGKEDIARVAAISAASEEVGKLIADAMERVGNDGVITVEESKSMGTDLEVVEGMQFDRGYVSAYMVTDTEKMEAVLDDVYILITDKKISNIQEILPILEQIVQQGKKLLIISEDIEGEALSTLVLNKLRGTFTCVGVKAPGFGDRRKEMLQDIAILTGGEVISEELGRDLKDVTIDMLGTADSVKVTKENTTIVNGKGDKVAIKERVSQIRVQIEDTTSEFDKEKLQERLAKLAGGVAVIRVGAATETELKEEKLRIEDALAATKAAVEEGIVPGGGTAYIDIIPKIADLTSDIIDVKLGIDIIRKALEEPVRQIANNAGAEGSVIIEKVKASEAGVGYDALNDKYVDMLKTGIVDPTKVTRSALQNAASIASTFLTTEAAVADIPEKENTPPMAPGMGMDGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APJA_DANRE
Sequence: MEPTSEYTETYDYYDTGYNDSGCDYSEWEPSYSLIPVLYMLIFILGLSGNGVVIFTVWRAKSKRRAADVYIGNLALADLTFVITLPLWAVYTALGYHWPFGVALCKISSYVVLVNMYASVFCLTCLSFDRYLAIVHSLSSGRLRSRATMLASLGAIWFLSCLLAVPTLLFRTTVDDTGSNRTTCAMDFSLVTLNQDHESLWIAGLSLSSSALGFLLPFLAMTVCYCFIGCTVTRHFSHLRKEDQKKRRLLKIITTLVVVFAFCWTPFHVLKSMDALSYLDLAPNSCGFLHFLLLAHPYATCLAYVNSCLNPFLYAFFDLRFRSQCLCLLNLKKAMHGHMSSMSSTLSAQTQKSEVQSLATKV
What is the function of this protein?
Receptor for apelin receptor early endogenous ligand (apela) and apelin (apln) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:17336906, PubMed:24316148, PubMed:24407481).  Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively (PubMed:17336906, PubMed:24316148, PubMed:24407481, PubMed:26017639).  Positively regulates angioblast migration toward the embryonic midline, i. e.  the position of the future vessel formation, during vasculogenesis (PubMed:26017639).  May promote sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (By similarity).  Required for cardiovascular development, particularly for intersomitic vein angiogenesis by acting as a receptor for apln hormone (By similarity).  Also plays a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility, and heart failure (By similarity).  Acts redundantly with agtrl1b in heart development (PubMed:17336906).
What are the official names of this protein?
Apelin receptor A, Angiotensin II receptor-like 1a, Angiotensin receptor-like 1a, G-protein coupled receptor APJ A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Internalized to the cytoplasm after exposure to apelin (apln). After exposure to apelin receptor early endogenous ligand (apela), internalized from the cell surface into an endosomal recycling compartment, from where it is recycled to the cell membrane.