PharMolix/UniProtQA huggingface dataset:
Protein: RS11_STRPB
Sequence: MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: VIE1_HCMVA
Sequence: MESSAKRKMDPDNPDEGPSSKVPRPETPVTKATTFLQTMLRKEVNSQLSLGDPLFPELAEESLKTFEQVTEDCNENPEKDVLAELVKQIKVRVDMVRHRIKEHMLKKYTQTEEKFTGAFNMMGGCLQNALDILDKVHEPFEEMKCIGLTMQSMYENYIVPEDKREMWMACIKELHDVSKGAANKLGGALQAKARAKKDELRRKMMYMCYRNIEFFTKNSAFPKTTNGCSQAMAALQNLPQCSPDEIMAYAQKIFKILDEERDKVLTHIDHIFMDILTTCVETMCNEYKVTSDACMMTMYGGISLLSEFCRVLCCYVLEETSVMLAKRPLITKPEVISVMKRRIEEICMKVFAQYILGADPLRVCSPSVDDLRAIAEESDEEEAIVAYTLATAGVSSSDSLVSPPESPVPATIPLSSVIVAENSDQEESEQSDEEEEEGAQEEREDTVSVKSEPVSEIEEVAPEEEEDGAEEPTASGGKSTHPMVTRSKADQ
What is the function of this protein?
Plays an important role in transactivating viral early genes as well as activating its own promoter, probably by altering the viral chromatin structure (By similarity).  Expression of IE1 and IE2 proteins is critical for the establishment of lytic infection and reactivation from viral latency (PubMed:27466417).  Disrupts PML-associated ND10 nuclear bodies by interfering with host PML and SP100 sumoylation thereby altering the regulation of type I and type II interferon-induced gene expression (Probable) (PubMed:27903803).  Promotes efficient viral growth by interacting with and directing host SP100 to degradation, leading to enhanced acetylation level of histones (By similarity).  In addition, functions in counteracting the host innate antiviral response.  Inhibits the type I interferon pathway by directly interacting with and sequestrating host STAT2 (By similarity).  Also targets type II interferon pathway by repressing IL6- and STAT3 target genes (By similarity).  Repression of STAT3 genes is due to STAT3 nuclear accumulation and disruption of IL6-induced STAT3 phosphorylation by IE1 (PubMed:23903834).  This repression is followed by phosphorylation and activation of STAT1 (By similarity).  Inhibits host ISG transcription by sequestering host ISGF3 in a PML- and STAT2- binding dependent manner (By similarity).  Alters host cell cycle progression, probably through its interaction with host E2F1 or RB1 that overcomes the RB1-mediated repression of E2F-responsive promoters (By similarity).
What are the official names of this protein?
Immediate early protein IE1, IE1, 55 kDa immediate-early protein 1, IE1p72, IE72.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 IE1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Colocalizes with host PML-associated nuclear bodies very early post infection.
Protein: YR350_MIMIV
Sequence: MNRRNRSNDLNPEPSIENPNNQIAEEFPGNNSVYKSDGYVDLKNNGRLFPIWILKNFKQYKLPEIIRKENEDPCNVQVKLELRKYQEFVGQYLNPQGPYTSILLYHGLGSGKTASAINLMNILYNYDNGTNFIVLIKASLHNDPWMQDLKEWLGRDPSEQNVDNVTKLDRYKNIHFVHYDSPFADSSFMSVIKTLDLSKPTMYIIDEAHNFIRNVYSNINSKLGKRAKVIYEYIMKDKRENKNTRIVLISATPAINTPFELALMFNLLRPGIFPSSELDFNRTFVTESSYPILNPMKKNMFERRILGLVSYYIGATPDLYARQELKYINLPMSAYQYDIYRIFEKLEAEIQERARRRGKQSQLYRTYTRQACNFVFPYVNMNVNGELRPRPGKFRLSEKLADDFSKGKNLDVPDTEKEILNKYTKAIENYLNETERYFQNINKKDAENGRTIINDLDEFKKGFGTKFNSFLQYYQSEGPRSSLLTEMYNCSPKMLAIAFMTYISPGKVMIYSNYVVMEGIDVMKIYFRLIGFNDFTIAREYMGYCEYHGRIDPKDRVRIKNMFNDKNNVYGNKCKVIMLSPSATEGIQLLDIRQEHIMEPYWTEVRIQQVIGRGVRQCSHRDLPMSERIVDIYRYKVIKPENLDPDDTVRQSTDEYVEDQAKSKANLIESFLGAMKEAAVDCELFKEHNMMSQSYYCFKFPESAVTKTNVGPAYREDIKDDVKYDSGLNSKNSIVERIRVVKVNAVYQINTDNNNPVYSSPTKYWYNKKTGMVYDFETHYPVGQVEFIDNLPNKLDKDTYIMRIDVIIPSITGSVNT
What are the official names of this protein?
Putative ATP-dependent RNA helicase R350.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion.
Protein: BCHN_JANSC
Sequence: MNTPKSIPSGTCRDTPVLKERGQREVFCGLTGIIWLHRKMQDAFFLVIGSRTCAHLLQSAAGVMIFAEPRFGTAILEETDLAGMADAHEELDREVERLLSRRPDIKQLFLVGSCPSEVIKLDLARAAERLTQVHAPHVRVLNYSGSGIETTFTQGEDACLTSMVPVLPTTDQKELMLVGALPDVVEDQAVSLLSQMGIGPIRVLPAPRTAETPGVGPNTVFACLQPFLGDTAAALTRRGAHHIQAPFPFGEEGTTLWLRAIADEFGVDDDTFDRVTAAPRARARKAIANASEHLNGKSVFFMPDSQLEIPLARFLTRECGMEAIEIGQPFIHKGLVGPDLDLMPAGPTISEGQDVDKQLDRVRAAQPDLTVCGLGLANPLEAEGLTTKWAIELVFTPVHFYEQAGDLAGLFSRPVRRRAVLKLEAAE
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: RIP51_CRIRI
Sequence: IVSYPDDAGEHAHKMG
What is the function of this protein?
Has no antimicrobial activity.  Does not inhibit the formation of NO by neuronal nitric oxide synthase.
What are the official names of this protein?
Riparin-5.1.
What are the subcellular locations of this protein?
Secreted.
Protein: TNNI2_MOUSE
Sequence: MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRRESEKENYLSEHCPPLHIPGSMSEVQELCKQLHAKIDVAEEEKYDMEVKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES
What is the function of this protein?
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform.
What is the protein family that this protein belongs to?
Belongs to the troponin I family.
Protein: MSRB_ACIB5
Sequence: MGKVNKTDREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQHGTYVCRCCGAELFSSDAKYDSGCGWPSFFRPLNGSVIDEHEDLTHGMVRTEIVCHDCEAHLGHVFEDGPQPTGLRYCVNSASLQLKTQEKNDEETYP
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: ATPD_METNO
Sequence: MAQNGSESGSTLGGVAGRYASALFELAREERAVDAVSEGLDRFDALLKESADLQRLVRSPVFTSEDQVKAIDAVLARAGITGLAANFIRLSAANRRLFVLPDMIRAFRALVRESKGIVQAEVRLAETPSDAVLEEIKASLRDVARAEVDVDLRIDPSLIGGIVVKVGSRMVDASLRTKLNSIRLAMRDAR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NTPPA_BACSU
Sequence: MTKPLILASQSPRRKELLDLLQLPYSIIVSEVEEKLNRNFSPEENVQWLAKQKAKAVADLHPHAIVIGADTMVCLDGECLGKPQDQEEAASMLRRLSGRSHSVITAVSIQAENHSETFYDKTEVAFWSLSEEEIWTYIETKEPMDKAGAYGIQGRGALFVKKIDGDYYSVMGLPISKTMRALRHFDIRA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  Can also hydrolyze CTP and the modified nucleotides pseudo-UTP, 5-methyl-CTP (m(5)CTP) and 5-methyl-UTP (m(5)UTP) (PubMed:24210219).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids (PubMed:24210219).
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Multicopy associated filamentation protein, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase, Septum formation protein Maf.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_CLOAC
Sequence: MKTDIQIAQEAQMKHIKDVAELIDIHEDDLELYGKYKAKVSLDVLDQLKDKPDGKLVLVTAINPTPAGEGKTTTNIGLSMGLNKLGKKTSTALREPSLGPSFGVKGGAAGGGYAQVVPMADINLHFTGDFHAITSAHSLLAALVDNHLHHGNALRIDTNRIVWKRVVDMNDRALRKIVVGLGGKAQGITREDGFDITVASEIMAILCLANDREDLKERLGNMVVAYNVDGDAVRAKDLEAQGALTLILKDAINPNIVQTLENTPAFIHGGPFANIAHGCNSVLATKLALKTGDYAVTEAGFGADLGAEKFFDIKCRYAGLNPDVAVIVATVRALKMHGGVAKEDLGTENLDALAKGMTNLERHIENVAKFGVPSVVAINAFPTDTEAEKQLVFDKCKEMGVDVAISDVFAKGGDGGVELAQKVIDVCENKKSDFKVLYDVEESIPEKITKIAKEIYRADKVNFSKAAKKQIAELEKLGLDKLPICMAKTQYSFSDDPALLGAPEGFELTIRDLELAAGAGFIVALTGDIMRMPGLPKVPAANRMDVLPNGEIIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: BLTX_BLABR
Sequence: MCFLLLCLTLTLAGTGAVPTGPSIEIHSRIIGGWECDKHSQPWQALLTFTRKHNSVCGGVLVHSQWVLTAAHCIGDNYKVLLGLHDRSSEESTVQEARVSARFPHPLYNMTLLNLLLSHKMNLTFFYKTFLGADFSHDLMLLRLDQPVQLTDAVQVLDLPTQEPQVGSTCHVSGWGRTSQNYENSFVLPEKLQCVEFTLLSNNECSHAHMFKVTEAMLCAGHMEGGKDSCVGDSGGPLICDGVFQGIASWGSSPCGQQGRPGIYVKVFLYISWIQETIKAHS
What is the function of this protein?
Has kallikrein-like activity, converts kininogens to kinins, and has dilatory effects on the blood vessel walls.  Shows highest activity toward Pro-Phe-Arg-MCA and Boc-Val-Leu-Lys-MCA in vitro.  Has preference for Arg and Lys in position P1 and hydrophobic residues in position P2.
What are the official names of this protein?
Blarina toxin, BLTX.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CFXQ_MIMIV
Sequence: MKRSHDSITRSINSDNDSETNMNSDNNNNNKPNQRKKINLNKKPSIFFIFDDLTDYETENKETTTIPPICHGIHCDHDPNSCIVPIIPDKFNNMTRLNLDNLIELGELFHCKLQKNFRNIPLERLAILRESLLKLNKTIGMNSIKESICEQLIYFLMDLEPNPQEMLHTVIQGPPGVGKSYVIDILAEIYLKMGYLSNGKINKVKLDELKGKYIGHSAPLTQKAIDNSIGGVLVLDEVYAIGNSDHLDSFSKEVIDTINRNLTEKAGKFVCIIAGYGEQIDKCFFAHNEGLRSRFRFRFSIDSYTPEELFEIFKLKVENDKWKLSESEINLITDFFRFNRDKFPYFGRDIETLLFHTKVAHSNRIVYNDNSGLNKTINLLDIKQGFAKFSLNNKETSNNDFNLMYL
What are the official names of this protein?
Putative cfxQ-like protein R730.
What is the protein family that this protein belongs to?
Belongs to the CbxX/CfxQ family.
Protein: RS17_WIGBR
Sequence: MKKKKVEIIMGKKKLQILKGSVIKNKMQKSIVVSVERFVKHPIYKKFMKKTTKLHVHDENNSSKVGDVVEIQECRPISKTKSWKLINIKKNN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SNF5_SCHPO
Sequence: MDKDIGSAVAELQVCSTHYAMTIVSCGFHSPQSLMNADLQHCLLADQNYLLNNSNKNKGSIIEENTRKPFQSARNLQTSLKTHPESAITRYGLGYAGFGNGWTALKPKILFPSQKRRVKGRFTFPFSRRSNLAQSKLPVDLVPIRLEIDADRYKLRDSFTWNLYDKCISLDQFAEQICIDYDIPLHNVHIVQNISKSIQAQINDYEPRKAQSNLSFVSDVSSSTSETVYAHEPSDSLAKASKQQIPTVQNDLRILIKLDITIGRLNLIDQFEWNLFAPESSAEEFATVMCLDLGLSGEFCTAVAHSIREQCQMYIKYLSLIGYLFDGSEIEDEEVRSYILPPLKNTLRFSDMESSSFAPMIYELNDAEMERQDRGYDREARRMRRRQGRAKHGIMLPDLRDIPKIHRSLFPSSSVPSDDDFMHALSLSTNSDGETLNEINTNNPEREHLIVRLKVDSQKLKIIVEQSQTLTLNNFQQRKLTPLPNSMSFDSLNEFESERNTPSTYGQNISPLPQFSSPSLSSDAFLTNSNSSESALVHMQKLNLPDFTPSWVKRCVIETFAKFPNDRFNVIVKPALNPAERMTVRICCHDCINEYFTAGPGFTFGNFHIHLLSSSHQQKKEVRMNTVLDRNT
What is the function of this protein?
Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
SWI/SNF chromatin-remodeling complex subunit snf5, SWI/SNF complex subunit snf5.
What is the protein family that this protein belongs to?
Belongs to the SNF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COX2_NYCPR
Sequence: MAYPFQLGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALLSLRILYMMDEINNPFLTMKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVILPMEMTVRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMAMRPGLYYGQCSEICGSNHSFMPIVLEMVPLSYFETWSALMV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GCS2_PARPJ
Sequence: MSLEPFIDSKPFTFGVELEMQIVNTHDYDLTKAGSDLLRLIKDEKIPGNITPEITESMIELSTGICTTHEQAVTDLRKIRDTLVSAADHLNVGLCGGGTHAFQQWSERQIVDTPRFQYLSELYGYLAKQFTVFGQHVHIGCPDPNSALYLLHSMSRFIPHFIALSASSPFVQGVDTGFHSARLNSVFAFPLSGRAPFVLTWDSFEEYFSKMVHTGVVNSMKDFYWDIRPKPGFGTIEVRVMDTPLSVDRAAAIACYIQTLARHLLLDKPIAPQEDDYLVYTFNRFEACRFGLAGTCINPQTGERKTISEDILETLDLIAPHAEALGSGNALAEIGAIARGQVNDATWLRGVVEREKSLHEAVRQQCLQWRA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: DAPE_CAMFF
Sequence: MEVVEILKELLKFKSITPDDDGAMNFINMFMDGFDADFVDVNGIKNLILTKKFGDGVHLCFAGHIDVVPAGDGWDSDPFEPELKDGFVYARGAQDMKSGVAAFLCACKDATKFNGTLSIILTSDEEGDGIYGTLEALKFLKSRGNLPDFALVAEPTSSSTFGDTIKIGRRGSVNGVVTINGVQGHAAYPEKCVNPVHQLASVFSDFAGYELDSGSKYFGASKIVITDIRGGMEVVNVTPKSVKIMFNVRNSELTSCEDIKRYTEHIFNGFDFTLSLKESSKPFLTDESSKIVIQAQKSIENICKISPDLSTSGGTSDARYFAAFGVPVVEFGVVNDRIHAINERVLQSEVESLYLVFKDLIENFE
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PGK_DESPS
Sequence: MKSLRELELAGKRVLVRVDFNVPMDDKQRITDDIRIRMVLPTLRYVLEQGGRLIICSHMGRPKGKRVEEYSLAPIARHLAGLLGRDVGIAPDCIGAEVEAQVAALGVGEVLLLQNLRFYGEETENDAVFAGKLAGLADVYVNDAFAVSHRAHASVVGVAERVAEKCAGFLLQTEIDYFHKSMNDPIRPLVALVGGAKVSSKIGALENMLGKVDKMIIGGAMANTFLMSQGVDVGASKVEDDLLVTARNFLQAAGERGMKVYLPVDFVVADRFAADAVHKTVPADSVPEGWMALDVGPASSILFREALQGAGTIVWNGPMGAFEMDAFAGGTMSLCRDVAASQALSITGGGDSNAAVKKSGEADNISYMSTGGGAFLQLMEGKTLPGVDALEA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_PSEP1
Sequence: MGVLNEFKAFAVKGNVVDMAVGIIIGAAFGKIVSSFVGDVIMPPLGLLIGGVDFSDLAITLKAAEGDVPAVVLAYGKFIQTVIDFVIVAFAIFMGVKAINKLKREEAVAPTTPPVPSAEETLLTEIRDLLKTQNQNRLP
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS2_CERS4
Sequence: MDMALPEFSMRQLLEAGVHYGHQTARWNPKMAEFIYGDRNGIHIVDLTQTVPMLDQALKVVRDTVAKGGRILFVGTKRQAQKPIAEAAEKCAQHYMNHRWLGGTLTNWKTVSQSIQRLKQLDEVLATGAEGLTKKERLNMEREQQKLQASLGGIREMGGTPDLLFIIDVGKEDLAIAEAQKLGIPVVAVVDTNNSPKGVDYVIPGNDDAARAIALYCDLVSRAALDGMSAQMGAAGIDLGALDVAPEEETLEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: YOZO_BACSU
Sequence: MGIFSVSRSTDAKKLEALLVEGERIESIYKLRVDQICFTNKRIIFFDNKMFSKKKVRVFLPYKTIESFAIQEAGMFDPDTGLLLMTRSKTFELEFAKDTDLSEVQAVLTKHLCS
What are the official names of this protein?
Uncharacterized protein YozO.
Protein: RK23_VITVI
Sequence: MDGIKYAVFTDKSIRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKGRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: XCT_MOUSE
Sequence: MVRKPVVATISKGGYLQGNMSGRLPSMGDQEPPGQEKVVLKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTGSVGMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAFGRYILEPFFIQCEIPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQLIKGQTHHFKDAFSGRDTSLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAIITVGYVLTNVAYFTTISAEELLQSSAVAVTFSERLLGKFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVHKHTPLPAVIVLHPLTMVMLFSGDLYSLLNFLSFARWLFMGLAVAGLIYLRYKRPDMHRPFKVPLFIPALFSFTCLFMVVLSLYSDPFSTGVGFLITLTGVPAYYLFIVWDKKPKWFRRLSDRITRTLQIILEVVPEDSKEL
What is the function of this protein?
Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane (PubMed:10206947, PubMed:12235164, PubMed:16144837, PubMed:16037214, PubMed:17035536) (Probable).  Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for protection of cells from oxidative stress (PubMed:31396687, PubMed:16144837, PubMed:16037214, PubMed:17035536).  The transport is sodium-independent, electroneutral with a stoichiometry of 1:1, and is drove by the high intracellular concentration of L-glutamate and the intracellular reduction of L-cystine (PubMed:10206947).  In addition, mediates the import of L-kynurenine leading to anti-ferroptotic signaling propagation required to maintain L-cystine and glutathione homeostasis (By similarity).  Moreover, mediates N-acetyl-L-cysteine uptake into the placenta leading to subsequently down-regulation of pathways associated with oxidative stress, inflammation and apoptosis (By similarity).  In vitro can also transport L-aspartate (By similarity).  May participate in astrocyte and meningeal cell proliferation during development and can provide neuroprotection by promoting glutathione synthesis and delivery from non-neuronal cells such as astrocytes and meningeal cells to immature neurons (PubMed:17035536).  Controls the production of pheomelanin pigment directly (PubMed:16037214).
What are the official names of this protein?
Cystine/glutamate transporter, Amino acid transport system xc-, Solute carrier family 7 member 11, Subtle gray protein, xCT.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LAM2_CAEEL
Sequence: MTSILWLFSLAVLWHMGQPQPAELYPSVDPNHFGADGNPCYDRATRQPQRCVPDFVNAAFNLEVQVTNTCGTKRPTKFCVQSGHTGQRSVCETCDDRHEGFSHPAKYLTDFNVGNNETWWQSDTMQEGQQYPTTTNLTLVLGKSFDITYVRLKFISPRPESFTIYKKTHTDSEWEPWQFYSGSCRATYGLSDRAPILPGNEATAQCTKEFSDISPITGGNIAFSTLEGRPSAHAFEESEVLQKWVTASAIRISLNRMNTFGDEVFKDPQVLRSYYYAISDFAVGGRCKCNGHASECVGSSSVDGENRLVCRCEHNTQGADCNECLPFYNDRPWRSGTSVEANECIACNCSQLSNRCYFDQQLFEETGHGGHCIDCQGNTQGVHCEQCIANHWRRPGENYCVACGCNEIGSLSTQCDNEGKCQCKPGVTGRFCDQCLDGFYDFSTNGCKNCGCETSGSLNNQPRCDSSSGSCSCKLNVEGRQCDKCKPGYFDLSTENQFGCTPCFCFGHSSICNTADGYFAMNVSSVFDQDKQKWAGQNRIGLQDTQWAELDKAVAVSDTDNSPVYFVAPEQFLGDQRSSYNQDLVFTLKVAKHVTNQDVKDIIIVGADRQELSTSITAQGNPFPTTEAQTYRFRVHADPYFGWYPRINELDFIGILSNITAIKIRGTYSYKDIGYLSNVNLGTAGVAPSAANPKQATWIEHCECLPGFVGQFCESCESGFRRETKFGGPFNHCIKCDCHNHSNSCEAESGSCICEHNTAGDTCERCARGYYGDALQGTEEDCQKCPCPNDGPCILHADGDVICTECPNGYTGRRCDECSDGYFGNPKDGTECVECACSGNTDPNSIGNCDKITGECKKCIFNTHGFNCENCKPGYWGDALIEPKGNCQSCGCFAAGTRRPNNDYTLLECNQQDGQCDCLPNVIGIQCDQCAHGFYNITSGLGCQECNCDPLGSEGNTCDVNTGQCQCKPGVTGQRCDRCADYHFGFSANGCQPCDCEYIGSENQQCDVNSGQCLCKENVEGRRCDQCAENRYGITQGCLPCDDCYTLIQSRVNVFREKVKSLDNTLQEIIENPAPVNDTKFDEKVKETSRAASEVWEAVKQKTKEGGGTIKTKSKAIKDEIVAALEKLTSIDESVAQAKVGADAAENDMKRWEIIIENARREIENVLHYLETEGEERAQIAYNASQKYGEQSKRMSELASGTREEAEKHLKQASEIEQLSEQAIANATQANKEASDAIYGGEQISKQIAELKEKQNQLNESIHRTLDLAEEQKKSADEANNLAAVSLTNVEAVKIPSVDPKELRNDVAGVLEESENLVDSSVKENSANDELFDEVNRSVADARNELQSSQDQQRVSDQLMLELEKSRERIVDSVSTADKTLKDAEAALQVLEEFGAKIEKSRNDAVAEFAGVEGINQRLDDIIDAQDKRRNSLPIDKQFVIDYRKSADVLLNETHALADRYKDIIHSDVDTRDSTEAVQYDIEQLMEELTDSNENLQYYKKQAEDDKQMATEAVRKATLAKNSAIEANATILAEEDEIKKIINSLDTMEEVNNAELDELEEEIDRLDQLLAQAQLAKEVPTYQQYRADEDVKVAQLKNDISELQKEVLNLEEIRDNLPTKCFNVINLEQEGQK
What is the function of this protein?
During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3.
What are the official names of this protein?
Laminin-like protein lam-2.
Protein: RNZ_SALRD
Sequence: MKIDVIPLGTASAVPTDERHLSALAVERKGQVLLFDCGEGTQYRLREAGLSWARIEAIFVTHLHGDHCYGLPGLLSTMELQQRADPVTLVLPPGGPAMLRAVPGATPARLSFPVHVVEADAAGTLGTVYETDEIAVEARRLDHREVFAMGFRVAERTRPGRFDPERARALGVPEGPAFGRLQNGCPVTTPDGTTVRPGQVLGPPRPGVVAAYVTDTRPCAGGRALAEEADLLYHDATFADDHAARADETGHSTARQAATVAREAGATRLLLGHLSARYPDPAPQEREARSVFPAAEVAEELRRYELDPREKEPDPVGPADES
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.