PharMolix/UniProtQA huggingface dataset:
Protein: HTPG_MYCTA
Sequence: MNAHVEQLEFQAEARQLLDLMVHSVYSNKDAFLRELISNASDALDKLRIEALRNKDLEVDTSDLHIEIDADKAARTLTVRDNGIGMAREEVVDLIGTLAKSGTAELRAQLREAKNAAASEELIGQFGIGFYSSFMVADKVQLLTRKAGESAATRWESSGEGTYTIESVEDAPQGTSVTLHLKPEDAEDDLHDYTSEWKIRNLVKKYSDFIAWPIRMDVERRTPASQEEGGEGGEETVTIETETLNSMKALWARPKEEVSEQEYKEFYKHVAHAWDDPLEIIAMKAEGTFEYQALLFIPSHAPFDLFDRDAHVGIQLYVKRVFIMGDCDQLMPEYLRFVKGVVDAQDMSLNVSREILQQDRQIKAIRRRLTKKVLSTIKDVQSSRPEDYRTFWTQFGRVLKEGLLSDIDNRETLLGISSFVSTYSEEEPTTLAEYVERMKDGQQQIFYATGETRQQLLKSPHLEAFKAKGYEVLLLTDPVDEVWVGMVPEFDGKPLQSVAKGEVDLSSEEDTSEAEREERQKEFADLLTWLQETLSDHVKEVRLSTRLTESPACLITDAFGMTPALARIYRASGQEVPVGKRILELNPSHPLVTGLRQAHQDRADDAEKSLAETAELLYGTALLAEGGALEDPARFAELLAERLARTL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_STUS1
Sequence: MIDSDGFRPNVGIILTNDVGQVLWARRINQDAWQFPQGGINARETPEEALFRELNEEVGLEEQDVKILACTRGWLRYRLPQRLVRTHSQPLCIGQKQKWFLLRLTGAEDRVRMDLTGKPEFDGWRWVSYWYPLGQVVTFKREVYRRALKELAPRLPVRD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: LSPA_PSEAB
Sequence: MPEVDRFGRLPWLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIVVSAILVVWLKRLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNRWYFPAFNLADSAITVGAVMLALDMFRSKKSGEAAHG
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PIN2_CAEEL
Sequence: MMTNAAQITKQRNSGKRHRACERCREQFELNEPYFLLGASSWHMRCFLCAQCMDPLVGTTYFQFENRIYCEHDFKTLYAPVCAKCNEFVIGQVVHSSNNSYHLACFTCDECNVHLNSQIAYRYQGTILCFLCNQKKPKMRIYNCNKCKQHVDNSDLLTYQENPYHAYHFKCTTCKKVLESDARTIKDDLFCPRCFDFKCEVCFDCKKVIDPQVEQSIFTMNKHWHTDHFRCATCARPFFGHEHYEKNGKAYCRDDFLELIGHHCFICDRNVGGGMVHVFGKAFCPECYRCRGCDKVLHYKDKVMELDLMPLCKKCLGNKTFQKALKYKSL
What are the official names of this protein?
LIM domain-containing protein pin-2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NRPA_METMA
Sequence: MHCLECGLVYIVSGLKVPEKISVRVFVNRIEHPFTHWVKLNAGELLREDEEIILDKVKTGYGSPFVITSLQIGVRRVPSALAEELDTIWARPLNEITFAKRRKIRQKHPMSFENITSTAGTSTASEYLEVVDES
What is the function of this protein?
Involved in nitrogen regulation.  Enhances the transcription of the nitrogen fixation (nif) operon under nitrogen-limited conditions.  Acts by binding to the nifH promoter region.
What are the official names of this protein?
Nif-regulating protein A.
Protein: EDAR_ORYLA
Sequence: MKMWKRRGQKKSMFLSSLLVCCMFASAEYSSCGEYEFFNQTSNSCQACPQCRPGQEPNMSCGHGMKDEGFACVPCPQGKYSKGKYEICRRHKDCNALYKATVREPGTAEKDAECGPCLPGYYMLENRARNLYAMVCHSCQNAPLNTKECKKTTEAIIKPPINPGSTTVLPHPGSPGQGHLATALIIAMSTIFIMAIAIVLIIMFYILKAKPNGQACCSGQVVKAVEAQTNKLEDKKDVPDNVVIFPEKEEYDKLKASPQKTVKSENDASSENEQLLSRSIDSDEEPTSDKLRSSEATNHNLCQANVGYKPDLCLLSLGLLDHRVVCNGTPASAGSQANNTQAPNHITSSNVSSMNAINNNNKTPGMLQSRRKKILDLYARTCHVTEGLSPTELPFDCLEKASRMLSSSYSSDAAVVKTWRHLAESFGLKRDEIGGMSDGLQLFERVSTAGYSIPDLLARLVQIERLDAVESLCADVLGSNEIVALVGRQSVNSFHSQLVCPSPCTSPSPRCASV
What is the function of this protein?
Receptor for EDA (By similarity).  May mediate the activation of NF-kappa-B and JNK.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member EDAR, Ectodysplasin-A receptor, Protein reduced scale-3, RS-3.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS11_DEHM1
Sequence: MAVKKRAGAKKKEKKVIPVGKAFVQATFNNTIVTLTDLQGNVIAWASCGTAGFKGSRKGTPYAAQMAAQAAARKAAESGLRQVEVLVKGPGSGREAAIRSLQASGINVTAIRDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RUVC_PARP8
Sequence: MRILGIDPGLRVTGFGVIDQSGHQLTYVTSGVIKTADADLPTRLGTIFEGISTLIRQHAPDHSAIEKVFVNVNPQSTLLLGQARGAAICGLVSGGVPVAEYTALQLKQAVVGYGRATKEQMQQMVVRLLCLSGIPSTDAADALGMAICHAHGGGTLSTLGGIAPGLAKKGLRVRRGRLVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: EXOS6_MOUSE
Sequence: MPGDHRRIRGPEESQPPQLYAAEDDETPAARDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGSGPAGAGGEAPAALRGRLLCDFRRAPFSGRRRRAPQGGGGEDRELGLALQEALEPAVRLGRYPRAQLEVSALLLEDGGCALAAALTAAALALADAGVEMYDLVVGCGLSLTPGPSPTWLLDPTRLEEEHSAAGLTVALMPVLNQVAGLLGSGEGGQTESWTDAVRLGLEGCQRLYPVLQQCLVRAARRRGAAAPP
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes (By similarity).
What are the official names of this protein?
Exosome complex component MTR3, Exosome component 6, mRNA transport regulator 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: SYV_GRAFK
Sequence: MAIASQYNAKKVEDKWYDYWMKNNYFHSEVDDREPYTIVIPPPNVTGVLHMGHMLNNTIQDVLVRRARLKGLNACWVPGTDHASIATEAKVVAKLKAEGIDKNDLTREEFLQHAWEWTHKHGGIILQQLKHLGASCDWERTKFTMDDDMSASVIKVFVDLYEKGLVYRGYRMVNWDPQAKTTLSDEEVNYEERNGKLYHLKYKIDGTEDYLTIATTRPETILGDTAICINPNDERFTHLKGKKAIVPICNRTIPIIEDEYVDMEFGTGCLKVTPAHDENDKNLGDKHDLDVIDIFNDDATLNNYGLHYEGKDRFVVRAEIVEELELYGFLDKVEDHINKVGTSERTGAVIEPKLSDQWFLKMKEMAQPAIKAVLGDDINLVPEKFLNTYRHWMENVRDWNISRQLWWGHQIPAYFYGKGKNDFVVAETLNQAVLKAREVTGNAELQASDLTQDKDALDTWFSSWLWPMSVFNGILEPENKEIEYYYPTNDLVTAPEILFFWVARMIMAGYEYRGERPFKNVYLTGIVRDKQRRKMSKSLGNSPDPLGLIEQYGADGVRVGMLLSSPAGNDLMFDEDLCKQGSGFTNKIWNAFRLVKGWEISEKIEQPETAKMAINWYTARFQKTIREIEDHYSKYRISDALMSTYKLIWDDYCSWFLEMVKPGYGEPMDAKTYKAIIAILEENLKILHPFMPFVTEEIWQEITERTPEEALIIAKWPVEKEFDETIIKEFSHAAEVIAGVRKIRKDKNISFKNEIDFSVLNNENTSKTFDGVISKMGNISNLEYVTGSVDGALSFRVRSNEYFIPIAGAIDVEAEKEKIQEELNYTEGFLKSVDKKLSNERFVNNAPEKVVAIEKAKKADAEAKIEALKASLKSLS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_PROMP
Sequence: MSDKNSSQKNWTSWHHLLHKEILGNKTLIPDGANLLIAVSGGQDSMALLNLINDMKTQHNWFVNVWHGDHQWHKKSAKYALELKSYCNKKNISFFFDQANKNNISSEEKARDWRYKKLSERANQLLIENQKEIDIYLLTGHTNTDNAETFLLNLARGSNYAGLSNINKKRLLKHHIFLIRPLLIFSREDTKKFCQLQNIPIWEDPTNCDLTIKRNIVRKEIIPILETMYPGCSKRINSFAEKMSNYKNEQNDLSKLASLYCEDAIGVKRELLNSLCIEARCTILNTFLKKDCTKQLSSKNLTHLASSILVKDRGKIDLPDGFEIVWNKDYINLEKN
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFR1_YEAST
Sequence: MEGSYLSAQENQPIPERLIPRSNSTSNLFALSSTFSKLNVRNDADYNYSNPNKKRHIYSGEIDCRSVTAARKFPVRSCSMTAAQQRKRTALFTVRERNSYHEGFNNDQDYVSQYQKPQYTFGVYKELTPYQLQRSKMKRSFQFPNGEIYKPKLDGKCTHSLKKPELNSRDSSLFKFSEKKGRNLSKDFVGPHNGTSVIHIPPNDTGYGVNSLELNTSVPSTIKSSVSSTSPISAVNTLTSLPESQTDDDDGYENKTVTISYCFENTVNEKHGSHIEKLDLSTKEKTKPTTNSGLFDRKKKTILGTEKYRCIKSQSKLKLGSVLKKLWRTSGNSNTKHGKKDTKRRRIPIDDMVTHSDGNSEAENDIELMDANLDGIEFDDDETLMDTDSIFDDLLSKENDKYDLRRRQLEIRQKLHETSHNDDGKVSFRDTEKHNVNEGLIDKTIIEEFSKLGEYIIDTRNQPPPRSSKRPSLDDNESARYFYNISTDLRQSLSGPISLPMHVGNDMVNRLRNDWEYIRFEDRRNSLPDSSFDKVETPPKPIKKDVRFAKEVCLASTWSSNAYERANPEFIMNRHRLLWMMKVHPSMNSAMNEIKLELNSYKKNEMVVHENSKCFTHYLI
What is the function of this protein?
Acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation.
What are the official names of this protein?
Protein AFR1.
What is the protein family that this protein belongs to?
To yeast YER158C.
Protein: OBG_YERPY
Sequence: MKFVDEAAILVVAGDGGNGCVSFRREKYIPNGGPDGGDGGDGGDIYLLADENLNTLIDYRFVKSFRAERGQNGQSRDCTGKRGKDITIKVPVGTRVLDQGTGEIVGDMVRHGQRLMVAKGGFHGLGNSRFKSSVNRAPRQKTMGTEGETRELMLELLLLADVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLIPSLGVVRMDYEQSFVIADIPGLIEGASDGAGLGIRFLKHLERCRVLLHLVDLAPIDESDPAENAKVIVNELQQYSENLAEKPRWLVFNKIDLIDPEEAEKRAKAIVETLGWEGKYYMISAANRDNVNALCWDVMSFLNSQPKAMAIAESVPEKVEFMWDDYHREQLAEVEAEAEDDWDDDWDEEDDDGVEIIYER
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BURL3
Sequence: MGQKIHPTGFRLAVSRNWASRWYANNNNFAAMLQEDIGVREYLKKKLKNASVGRVVIERPAKNARITIYSSRPGVVIGKKGEDIEQLKTELQRRMGVPVHVNIEEIRKPETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRLGAQGIKIMSAGRLNGIEIARTEWYREGRVPLHTLRADIDYATSEAKTTYGIIGVKVWVYKGDTLGRNDAPVVEEVAEDKRPRRNARPGDRRPRRDGEGGAPGARRGAPRRGAGKPEDGKTGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: HDOX2_STAAE
Sequence: MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme oxygenase (staphylobilin-producing) 2, Heme-degrading monooxygenase 2, Iron-regulated surface determinant 2, Iron-responsive surface determinant 2.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ECO55
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
Protein: RISB_MANSM
Sequence: MKVLEGGLAAPNAKVAVVVARFNSFINDSLVEGAVDALKRIGQVKDENITLVRVPGAYELPLAVRRLADSKKYDAIVALGTVIRGGTAHFEYVAGGASNGIGHVSLESNVPVAFGVLTTENIEQAIDRAGTKSGNKGAEAALVALEMVNLLAQINA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: AROQ_PROM0
Sequence: MMNILLINGPNLNLLGTREPEIYGNKTLSDIEKDLTKVAKEKSINLECFQSNHEGEIVDKIQESVKSIQGILINAGAFTHTSISIRDALIGSKIPFVELHISNIFSREDFRKESFLTDKAIGIISGFGISSYSLALEGIIGYLSIKD
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PYRH_OCEIH
Sequence: MTTARYNRVVLKLSGEALSGDQGYGIDPKVIQSISKQVKEVADLGVEVAIVVGGGNIWRGKVGSEMGMDRASADYMGMLATIMNSLALQDGLETIDVETRVQTSIEMRQVAEPYIRRKAIRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEAEVILMAKNNVDGVYTDDPKLNKSAKKYESLTYLEMLNEGLGVMDSTASSLCMDNNIPLIVFSIMEEGNIKRVVQGETIGTTIRGK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRET_THELN
Sequence: MYEVTKFGGEGKRLEDYREIIGDEALEAIKAKAENLKDKSFVHVNSTSFGGGVAEILHNLVPLMRDVGIDARWFVIEGTNEFFNVTKSFHNALQGNKELRLTEEMKKLYLEINKKNAEDIDLTQFDYVLIHDPQPAPLIEFYEKRQPWIWRCHIDLSDPNLEFWKFLRQFVEKYDRYIFHMEEYVQEDLNQEKVVIMPPSIDPLSEKNMELSESEILKTLERFDVDPERPIITQVARFDPWKGVFDVIDVYRKVKEKIPEVQLLLVGVMAHDDPEGWIYFEKTLRKIGEDYDIKVLTNLTGVHAREVNAFQRASDVILQMSIREGFGLTVTEAMWKEKPVVGRAVGGIKLQIVDGKTGFLVKDVNDAIEKTLYLLEHKDVAQEMGKNAKERIKENFIITKHLERYLDLLNSF
What is the function of this protein?
Synthesizes trehalose from ADP-glucose and glucose.  Has a much lower activity toward UDP-glucose and GDP-glucose.  The reaction is reversible, the equilibrium strongly favors trehalose synthesis.
What are the official names of this protein?
Trehalose synthase, Trehalose glycosyltransferring synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: RB3GP_MOUSE
Sequence: MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGPSLGKPLEKGIFTSGTWEERSDEISFADFRFSVTHHYLVQESPDKERKDEELEDAIPQSMQDLLCMNNDFPPRAHCLVRWYGLREFVVIAPAAHSDAVLSESKCNLLLSSISIALGNTGCQVPLFVQIHHKWRRMYMGECQGPGVRTDFEMVHLRKVPSQYTHLSGLLDIFKSKIGCPLTPLPPVSIAIRLTYVLQDWQQYFWPQQPPDIDALVGGEVGGLEFGKLPFGACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPVQAPHWSVRVRKADNPQCLLGDFVTEFLKICRRKESTDEILGRSTFEEEGREVADITHALSKLTEPAPVPIHKLSVSNMVHTAKKKIRKHRGEESPLNSDVLNTILLFLFPDAVSEKPLDGTTSIDNSIPAPEAGDYTLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGSPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSLSDSTTSAYPGDAGKTGGQLGLDHLRDTEKEKGEVGKSWDSWSDSEEEFFECLSDTEDLKGNGQESGKKGGPKEMANLKPEGRLHQHGKLTLLHNGEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMESFKAANPGCFLEDFVRWYSPRDYIEEEVTDEKGNVVLKGELSARMKIPSNMWVEAWETAKPVPARRQRRLFDDTREAEKVLHYLAMQKPADLARHLLPCVIHAAVLKVKEEESLENIPSVKKIIKQIIAHSSKVLHFPNPEDKKLEEIILQITTVEAIIARARSLKAKFGTEKCEHEEEKEGLERFVSCLLEQPEVSVTGAGRGHAGRIIHKLFVNAQRAAAVALPEEELKKSGCPEERRQTLVSDFPPPAGRELILRATVPRPAPYSKALPQRMYSVLTKEDFRLAGAFSSDTSFF
What is the function of this protein?
Catalytic subunit of the Rab3 GTPase-activating (Rab3GAP) complex composed of Rab3gap1 and Rab3gap2, which has GTPase-activating protein (GAP) activity towards various Rab3 subfamily members (RAB3A, RAB3B, RAB3C and RAB3D), RAB5A and RAB43, and guanine nucleotide exchange factor (GEF) activity towards RAB18 (By similarity).  As part of the Rab3GAP complex, acts as a GAP for Rab3 proteins by converting active RAB3-GTP to the inactive form RAB3-GDP (By similarity).  Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones (By similarity).  The Rab3GAP complex, acts as a GEF for RAB18 by promoting the conversion of inactive RAB18-GDP to the active form RAB18-GTP (By similarity).  Required for recruiting and activating RAB18 at the endoplasmic reticulum (ER) membrane where it maintains proper ER structure (By similarity).  Required for normal eye and brain development (By similarity).  May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters (By similarity).
What are the official names of this protein?
Rab3 GTPase-activating protein catalytic subunit, RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAP.
What is the protein family that this protein belongs to?
Belongs to the Rab3-GAP catalytic subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction.
Protein: SAT_MICAN
Sequence: MTVLTEGIAPHGGQLINRIATAAEKAEFLALAEKLPRVSLDERALSDLVMIAIGGFSPLKGFMEQDDYEKVVDDMRLINGLPWAIPVTLSVREEVADPLKEGNWIRLDDSEGNFVGVLELTQKYRYNKAHEAVNVYRTDDQKHPGVKVLYEQGEINLAGPIWLLQRDPHPQFPKYQIDPLQSRKMFHEKAWKTIVGFQTRNPIHRAHEYIQKCALEVVDGLFLHPLVGATKSDDVPADVRMRCYEIMMDKYFPQDRVILAINPSAMRYAGPREAIFHAIIRKNYGCTHFIVGRDHAGVGDYYGTYDAQYIFDEFEPGELGIVPMKFEHAFYCTRTSGMATTKTSPSLPEERIHLSGTKVRELLRKGELPPPEFSRPEVAAELIRAMQGS
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: NU1M_ACACA
Sequence: MVSLTVYFILLSLYLILNVILTVAFLTLFERKVLASIQKRKGPNWTGFLGILQPLADALKLILKENPVPQNASSVLFFGGPLILLILSLSAWFVIPFNNETVVSDINIGILYVFMVSSLNTLNIIVAGWSSNSRYAFLGALRSIAQVIAYEVVIGIIIINIIVLSGSLNFLKIVWAQKDLWYAFVLWAQFFLFFIAMLAETNRHPFDLAEAESELVSGYNVEHSSVLFALFFLSEYANIILLCHVATILFLGGWTMPDLYFFIKFFSVEYYVSIDEFFYTLRSNFYYITWIYHSLVYIIKVYIYLFAFIWVRATLPRYRYDQLMRLGWKVFVPLTIGLVFISISLTLFFDGFPSEGGYINHFFSSDIFI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: METK_LEGJE
Sequence: MIIHVFTSESVSEGHPDKIADQISDAILDAILAKDPLARVACETFVKTGMVLVGGEITTSAWVDVETITREVIKDIGYNSSDMGFDWASCSVLSAIGKQSLDIAQGVDNRETKILGAGDQGLMFGYASRETDVCMPAPIAYSHRLMARQAELRKNNKLPWLRPDGKCQLTLKYDQGKPVAIDTIVFSTQHAPEISHKDLVEAVREEIIKPVLPEEWLSAATRYYINPTGRFVIGGPLGDCGLTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSGAYAARHVAKNLVAAGIAEKCEIQVSYAIGVAEPTSISVDTFGTGHLRNNVIIDLIKTHFDLTPQGIIDHHDLFSPIYRQTAAYGHYGRDGLPWERLDKVAALAKAL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLP_ZYGBA
Sequence: MSEFSELVRILPLDQVAEIKRILSRGDPIPLQRLASLLTMVILTVNMSKKRKSSPIKLSTFTKYRRNVAKSLYYDMSSKTVFFEYHLKNTQDLQEGLEQAIAPYNFVVKVHKKPIDWQKQLSSVHERKAGHRSILSNNVGAEISKLAETKDSTWSFIERTMDLIEARTRQPTTRVAYRFLLQLTFMNCCRANDLKNADPSTFQIIADPHLGRILRAFVPETKTSIERFIYFFPCKGRCDPLLALDSYLLWVGPVPKTQTTDEETQYDYQLLQDTLLISYDRFIAKESKENIFKIPNGPKAHLGRHLMASYLGNNSLKSEATLYGNWSVERQEGVSKMADSRYMHTVKKSPPSYLFAFLSGYYKKSNQGEYVLAETLYNPLDYDKTLPITTNEKLICRRYGKNAKVIPKDALLYLYTYAQQKRKQLADPNEQNRLFSSESPAHPFLTPQSTGSSTPLTWTAPKTLSTGLMTPGEE
What is the function of this protein?
Catalyzes the recombination between the large inverted repetitions of the plasmid.
What are the official names of this protein?
Recombinase Flp protein.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.