PharMolix/UniProtQA huggingface dataset:
Protein: RL22_SHEWM
Sequence: MEVLAKHRFARTSPQKCRLVADQIRGLPVAKALEILTFSPKKAAVLVKKVLDSAIANAEHNEGADIDELRVGAIMIDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y2111_CUPPJ
Sequence: MMKGQLAGLMKQAQQMQENMKKMQEQLAQIEVEGQSGAGLVKVVMTCKNDVKRVTIDPSLLADDKDLLEDLVAAAFNDAVRKAEATTQEKMGSMTSGLPLPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Reut_A2111.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CWLD_BACSU
Sequence: MRKKLKWLSFLLGFIILLFLFKYQFSNNDSWKPWSLPLSGKIIYLDPGHGGPDGGAVGGKLLEKDVTLEVAFRVRDYLQEQGALVIMTRESDTDLAPEGTKGYSRRKAEDLRQRVKLINHSEAELYISIHLNAIPSQKWSGAQSFYYGKYAENEKVAKYIQDELRRNLENTTRKAKRIHGIYLMQNVTKPGALIEVGFLSNPSEATLLGKPKYQDKVASSIYKGILRYFTEKGDPPE
What is the function of this protein?
Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan.  This is a step in the formation of muramic delta-lactam residues in spore cortex.
What are the official names of this protein?
Germination-specific N-acetylmuramoyl-L-alanine amidase, Autolysin, Cell wall hydrolase.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_STAAW
Sequence: MSKITEQVEVIVKPIMEDLNFELVDVEYVKEGRDHFLRISIDKEGGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFVSLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_SALTY
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVLEIVSGASRGIRLLQEEEDGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPSADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFTPIVVDLREQSFTIEGLAVGVIRNGEWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MIAA_RHIWR
Sequence: MNKSVSPKYPVALIAGPTASGKSALAIRLAEIADGVVINADASQVYADLRVLSARPDPAEEARAPHRLFGYRDAAEPCSAADWAADAKRAIAAAREAGKLPILVGGTGLYLRTLIFGIAPVPEIDPAIRAEVRALPVEAAHAALAAEDPAMGHLRPQDATRIARALEVIRSTGRSLSHWQAELTGGIGGEIAVAAAIVLPPRDWLRARCDARFEAMLDQGAVEEVKKLRARGLDPMLPAMQAIGVREIAAWQDGLIDRETMVAKAQAATRQYAKRQYTWFRHQPPAAWQRIDTQLNDNEIGKIAIKLRNDALTE
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: IF5A_DROME
Sequence: MAELDDQFETTDSGASTTYPMQCSALRKNGFVMLKSRPCKIVEMSTSKTGKHGHAKVHMVGIDIFSNKKYEDICPSTHNMDVPNVKREDLQLIAISDDSFLTLMTESGDLREDLKVPEGELGEQLRLDFDSGKDLLCTVLKACGEECVIAIKTNTALDK
What is the function of this protein?
mRNA-binding protein involved in translation elongation.  Has an important function at the level of mRNA turnover, probably acting downstream of decapping.  Critical for the efficient synthesis of peptide bonds between consecutive proline residues.  Can resolve ribosomal stalling caused by consecutive prolines during translation (By similarity).  Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.  Functions as a regulator of apoptosis.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y328_METJA
Sequence: MPNNTNNKLCKVCNSPHRAEIEALYFQGWGAKKISKYLKEKYNEDISYSAILRHMQNHVKPQLLEAIEEETTEIYSKMYKEIANNFGLALEGLFTMIKTAKKDLENPKATAREKEVAGRNLVMAIREMKELLQLTEDKEGADDIDL
What are the official names of this protein?
Uncharacterized protein MJ0328.
Protein: TFE_METVS
Sequence: MLDNPLIQQVLFEVMEEDVVGFDVLNVLIDSNEVTDDEISRQLEVKLNNIRRILYKLYEARLVDYNREKDEETNWYTYTWKPSLEKLPALVVKKMKNILDELKKQLSTEENGMFFYCMGCELKFTFEDAMDMGFRCPQCGGVLHEYDNKKDMATIKEQIAYIEDEFNQNPLFFKY
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: SYK_CAMUP
Sequence: LKSELKEDKE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_STRS7
Sequence: MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQENRFGELYPAVEQSEMVTITAYYPNSADIDDIRQTINQGLSRLKQCDVELGELTLTNQELAEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKLSLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLVKDEGYLIMSGIISEKLDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSN18_MOUSE
Sequence: MEGDCLSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYIVLAMGGLLFLLGFLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGDNDTDVFSATWNSVMITFGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRDGVVLSREECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVFAMCLFRGIQ
What are the official names of this protein?
Tetraspanin-18, Tspan-18.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HASTY_ARATH
Sequence: MEDSNSTASNVARAILAVVDFSSTSDTRKSAVQFLDSVKSGDVRVLAKTSFHLVKKEWSSEIRLHAFKMLQHLVRLRWDELSPPECRGLVNLSIELMSEVANASENWPLKSQSAALVAEIVRREGPDRWQEIFTLLTSLSAQGPLQAELVLMTLRWLPEDITIYNDDLEGDRRRLLLRGLTQSLPEILPLLYNLLERHFGAAMSEAGMQHFDLAKQHADVVIACLNAIVAYTEWAPVPDLARYGILSGCSFLLSSSDFRLHACEVFKLVCSRKRPSDASTAEFDSAISNLFQILTNASREFLCRSSSSSSVIDDNDYDFAVCMCESMASLGSTNLQSISSDGGVMAVYLQQMLGFFQHFKLGLHFEALLFWLSLMRDLLPKPKAATYPSGGGSSTGGDDSSSQVDSEKKKTLSLINDDISSAILDVSFQRMLKKEKVPTGIALSLGPLELWSDEFEGKGDFGPYRSKLLELIKLTASHKPLISSTKISERVITLIKHLLASPAPLQHVAVMDSQQLALDCIVATLFDGSNEFAGGSSEVHYALRGIFEGLLQQLLSLKWNEPELMKVHVHYLDAMGPFLKYFPDAVGSLINKLFELLTSLPHVVKDPATSTSRAARLQICTSFIRIAKAAEKSVLPHMKGIADTMGYLAKEGTLLRGEHNILGEAFLVMASSAGAQQQQEVLAWLLEPLSQQWIQPEWQNNYLSDPMGLVRLCSNTSFMWSIYHTVTFFEKALKRSGYRKSNLNTTSATTPASHPMAHHLSWMLPPLLKLLRVLHSLWSPSVFQTLPPEMRAAMTMTDAERYSLLGEANPKLSKGVSVYADGSFEGTKEGQAEASESDIRNWLKGIRDCGYNVLGLSTTIGETFFKCLDANYVAMALMENLQSMEFRHIRLFIHTFITYIVKSCPADMWESWLGVLLHPLFIHCQQALSSAWPGLLQEGRAKVPDLFGIQSGSDMKLEVMEEKLLRDLTREIATLFSTMASPGLNTGVPVLEHSGHVGRVDMSTLTDLHAFRSNSMVGFLLNHKSVALPALQICLETFTWTDGEATTKVCYFCGVVVLLAKLTNNVELREFVSKDMFSAVIRGLGMESNAINSPDLVNICREIFIYLSDRDPAPRQVLLSLPCLTPNDLHAFEEATAKTSSPKEQKQLMRSLLLLGTGNNLKALAAQKSQNVITNVTARTRLPASAPETIGAGVLWDEEFVQ
What is the function of this protein?
Nucleocytoplasmic transporter involved in the nuclear export of microRNAs (miRNAs).  Required for several miRNAs accumulation.  Specifically required for miR156 accumulation which targets SPL3, SPL4 and SPL5 transcription factors.  Involved in plant development through its role in miRNAs processing.  Required for vegetative phase change and vegetative to reproductive phase transition.  Functionally dependent on RAN1 binding.  Does not seem to be involved in small interfering RNAs (siRNAs) processing.
What are the official names of this protein?
Protein HASTY 1, Protein HASTY.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear periphery.
Protein: LRRT1_RAT
Sequence: MDFLLLGLCLHWLLRRPSGVVLCLLGACFQMLPAAPSGCPGQCRCEGRLLYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITELANTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLIKVNFAHFPRLISLNSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPYLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWLSNFQGRYDANLQCASPEYAQGEDVLDAVYAFHLCEDGAEPTSGHLLSAAVTNRSDLAPPESSATTLVDGGEGLHDSTLEPITVAIPGGEHAENAVQIHKVVTGTMALIFSFLIVVLVLYVSWKCFPASLRQLRQCFVTQRRKQKQKQTMHQMAAMSAQEYYVDYKPNHIEGALVIINEYGSCTCHQQPARECEV
What is the function of this protein?
Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.
What are the official names of this protein?
Leucine-rich repeat transmembrane neuronal protein 1.
What is the protein family that this protein belongs to?
Belongs to the LRRTM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane; Single-pass type I membrane protein.
Protein: HSP70_PYRSA
Sequence: MENKIEGVAIGIDLGTTYSCVGVWLHDRVEVIANDQGNRTTPSYVAFTETERLIGDSAKNQVAMNPDNTVFDAKRLIGRRFQDPAVQEDVKPFPFKVICKDGDKPAVEVKYKGETKIFAPEEISSMVLLKMKEIAESFLGKEVKNAVITVPAYFNDSQRQATKDAGAITGLNVLRIINEPTAAAIAYGLDKKTSGSKSERNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDSRLVNFFVSEFKRKYKKDVTSNARSLRRLRTACERAKRTLSSGTQTTVEIDSLIDGIDYYASITRAKFEELCMDLFRGTSEPVEKVLRDSKISKSEIHDVVLVGGSTRIPKVQQLLIDYFNGKELCKNINPDEAVAYGAAVQAAILAGDTSEKMDLLLLDVSPLSLGLETAGGVMTVLIKRNTTIPTKKTQVFSTYADNQPGVLIQVFEGERSRTKDNNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSASDKSTGKSNKITITNDKGRLSKEEIERMVEEAEKYKTEDEKLDKKLEAKNSLENYAYNIRNTVRDEKLKEKIQEEDKKSIEEKVKEVLEFIETNEDLEKEEYEEKEKELKNFANPIISKLYQQGSVPDMGNFSTGQNEQDDNANMGPKIEEVG
What are the official names of this protein?
Heat shock 70 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FDHD_LISMO
Sequence: MDIVSHQKIRRFEAGTFQEIESSVATEYPLTIYVNDQELVTIVCTPEYLEDLVVGFLTSEGIVRGPRDINSVDIIEATGHAKVSANFVNKFNAKYRGKRYITSCCGKSRENFYFQSDASLVNVKQNGNLQLTTDMIFRLMEKFEQNSATFHQTGGVHNAALCSSAEIIYSRMDIGRHNALDKIYGRALQDGTSTEDKAIIFSGRISSEILVKTAKLGCGIILSRSAPTELAINMAEELNITTVGFIRGDRLNVYSGFERIT
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_RALPJ
Sequence: MKTFSAKPHEVKRDWYVIDATDKVLGRVASEVAHRLRGKHKPEFTPHVDTGDFIIVINAAKLRVTGAKTTDKKYYRHSGYPGGIYETTFGKMQQRFPGRALEKAVKGMLPKGPLGYAMIKKLKVYAEGSHPHEAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MTRFR_DANRE
Sequence: MTLFFSHRLFTVWRLKCGVMDIGWPSVLPAAGKKYQIELPVVHEEELEEQFVRGSGPGGQATNKTSNCVVLRHIPSGIVVKCHETRSVDLNRKRAREILREKLEVAYKGEESELLKMKKESMQKKQDKRRKVNENIEKKRRFKEMLNSKQEDDKST
What is the function of this protein?
Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation.  As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes.  Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue.
What are the official names of this protein?
Mitochondrial translation release factor in rescue.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: THYX_RICTY
Sequence: MHNTTKRVTVPALEAMLYETIKVLDHGFIRVIDYMGDDSSIVQAARVSYGKGTKQLNQDKGLINYLLRHYHTTPFEMCDIKFHIKLPIFIARQWIRHRTASVNEYSARYSILGNEFYLPEPTDIASQSAINKQCRAGDSLPKKVSEKVLAILEEDARRCYMHYKELMNADEDGNIIDENVAGIARELARMNLTLNYYTEWYWKINLHNLLHFLRLRTDSKAQYEIRVYAGKILDIVKAWVPFTYEAFEEYRLQGANISRKGLEVIKRMIQGEKVIHETSGMNKREWEELVKIFR
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: PYRG_STUS1
Sequence: MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKVTMLKLDPYINVDPGTMSPFQHGEVFVTHDGAETDLDLGHYERFIRTRMTQNNNFTTGRVYEDVLRRERRGDYLGATIQVIPHITDEIKRRIIKGAGDADVALVEVGGTVGDIESQPFLEAIRQLRVEVGAKRAMLMHLTLVPYIATAGETKTKPTQHSVKELRSIGLQPDVLVCRSDRAIDVSSRRKIALFTNVEERAVISLPDADTIYKIPGILHAQGLDDYVVERFGLECRGADLSEWDRVVDAKLHPEKEVNIAMVGKYMELLDAYKSLIEAMSHAGIQSRTKVNLRYIDSEDIENQGTGLLEGVDAILVPGGFGLRGVEGKIATVRYARENKIPYLGICLGMQVAVIEFARDVLGWSDANSTEFDKDSGHPVVGLITEWADASGNTEVRTEASDLGGTMRLGAQECGLEPGSKVFECYGKERIVERHRHRYEVNNNLLPQLQAAGLKITGRSGDGALVEVVEAPDHPWFVACQFHPEFTSTPRDGHPLFSGFVNAALEYKAKKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ASNA_BRUMA
Sequence: MMENTLEPTLQNVINQTTLKWIFVGGKGGVGKTTCSCSLAIQLSQVRRSVLIISTDPAHNISDAFAQKFNKTPSAVNGFNNLYAMEIEANLGNDAQMVNPGVESSEGDIISLGRQVLQEMVGGLPGIDEAMSFSQMMKLIQSMDFDVVVFDTAPTGHTLRLLQFPTLIESSLGKLIGLQSSFAPLMTQMGGMLGLGEISADDTTNKLRETLDVVRRINSQFKDPDLTTFVCVCIAEFLSLYETERLIQELTKQNIDTHNIIVNQLLYPEEDENGCVKCKKCSARYGIQKKYLEQIADLYEDFNVTKLPLLESEVRGPGQLRNFSRYLIVPYDLNSSTVDNLTTH
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: MDR1_TRIEC
Sequence: MASQPPQPPSGQPDTQYEEYQSEVITETTNRPTPAADVYEITPTNDVMDDRYEHEHDDYESGAMYETVRTWSPQSRPELVRIASVFSRIDSHPDVAPTTEDGGQLNRRDTLAGVKIGDPVLDPTKPEFDFYKWARMFTHVMEKEGIKRNRTGVMFRNLTVLGSGSAVQYQDTFLSPFAAPFRPGELCGKGRNPEKVILHDFNGAIREGELLMVLGRPGSGCSTFLKAICGELHGLQKKKESIIHYNGVSQHTFKKELRGEAVYSAEDEHHFPHLTVGQTLEFAAAARTPSKRVLGLSRKDFSTHLARVMMSVFGLSHTYNTKVGDDYVRGVSGGERKRVSIAEIALSGAPICCWDNSTRGLDSATALEFTKALKIGSQVGGITQCLAIYQASQAIYDIFDKVIVLYEGRQIFFGPTRIAKQYFEEMGWYCPPRQTTADFLTSVTNPKERIAKEGYENRVPRTAVEFERYWKQSQNNKLLLADMDRFEAEYPPEEGHLEKLRETHGQAQAKHTASKSPYRISVPMQVKLCTVRAYQRLWGDKSSTIATNISQIMMALIIGSLFFDTPQTTDGFFAKGSVIFFAILLNGLMSITEINGLCKATDPIVPNAQRPIVVKHVNFAFYHAYSEALAGIVADIPIKFLLALVFNIIIYFLGGLERSAAKFFIFFLFTFITILTMSAIFRTLAAATKTIPQALALAGVMILALVIYTGFTLQPSYMHPWFKWILYINPIAYAYEALLVNEVHGNRYRCATPIPPYGSGTNFACAVAGAVPGEMSVSGDAWVESSYDYSYAHIWRNLGILLGFLAFFYFVYLVVSELNLSSASSAEFLVFRRGHLPKNFQGSKDEEAAAGGVMYPNDPARLPPTNTNGAAGETAPGGSTVAVIPPQKDIFTWRNVTYDITIKGEPRRLLDNISGWVRPGTLTALMGVSGAGKTTLLDALAQRTTMGVITGDMLVNGRPLDSSFQRKTGYVQQQDLHLETTTVREALRFSADLRQPKSVSRKEKYEYVEDVIKMLSMEDFSEAVVGNPGEGLNVEQRKLLTIGVELAAKPQLLLFLDEPTSGLDSQSSWSIVTFLRKLADNGQAVLSTIHQPSGILFEQFDRLLFLAKGGRTVYFGDIGKNSETLLNYFETHGAEPCGPSENPAEYMLNVVGAGPSGKSKIDWPAVWKESEESRHVQQELDRIQSETSKRNEGHGQSAEKEPGEFAMPFTSQLYCVTTRVFQQYWRTPSYIWGKLLLGLTSALFIGFSFFLQNSSMAGLQNSLFSIFMLTTIFSSLVQQIMPRFVTQRDLFEVRERPSRAYSWKVFLLANIIVEIPYQILLGIIAWASLFYPTFGAHLSSERQGILLLYCVQFFIFASTFAQMIIAGLPDAETAGGIATTMFGLMVTFNGVLQKPNALPGFWRFMWRVSPITYTVGGLAATSLHSREVKCAQNELAIFDPPSGATCAQYLQKLVEAGAPGKLYNPMSTSQCQYCPLSSGDQFLGGSEIHWSDRWRNFGIGWAYIVFNIFATVALYYLIRVRKSSGRPNRIISVITYHLSQFGTYCRAFITGRKEKCPRKREQIGKIY
What is the function of this protein?
Pleiotropic ABC efflux transporter that may be involved in the modulation susceptibility to a wide range of unrelated cytotoxic compounds.
What are the official names of this protein?
ABC multidrug transporter MDR1, Multidrug resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPE_BUCBP
Sequence: MKKFLLSSSVLSANFSRLGEDIFDVLKSGSDMIHYDVMDNHYVKNLTFGPIVLESLRSVEKIKSMVIDVHLMTCPVDDLIIKFAKLDVNIISFHPESTNNVEKTIKLIKSYGCKVGLALNPLTPLCVLDNVLDKIDLILLMSVNPGFPGQKFIPSILNKIRIVRELIDKSKKNILLEVDGGINLSNIFKIASFGTDIFVIGSAIFNSINYDLTIRSFRDVLKNINCKK
What is the function of this protein?
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
Ribulose-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: MT25B_HUMAN
Sequence: MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIIEFFTDNLWDTLPCSWQEALDGLKPPQLATMLLGMPGEGEVVRYRSVWPLTLLALKSTACALAFTRMPGFQTPSEFLENPSQSSRLTAPFRKHVRPKKQHEIRRLGELVKKLSDFTGCTQVVDVGSGQGHLSRFMALGLGLMVKSIEGDQRLVERAQRLDQELLQALEKEEKRNPQVVQTSPRHSPHHVVRWVDPTALCEELLLPLENPCQGRARLLLTGLHACGDLSVALLRHFSCCPEVVALASVGCCYMKLSDPGGYPLSQWVAGLPGYELPYRLREGACHALEEYAERLQKAGPGLRTHCYRAALETVIRRARPELRRPGVQGIPRVHELKIEEYVQRGLQRVGLDPQLPLNLAALQAHVAQENRVVAFFSLALLLAPLVETLILLDRLLYLQEQGFHAELLPIFSPELSPRNLVLVATKMPLGQALSVLETEDS
What are the official names of this protein?
Methyltransferase-like protein 25B, Protein RRNAD1, Ribosomal RNA adenine dimethylase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the METTL25 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NO70_SOYBN
Sequence: MAHQWVLNAPEPPSMLRQVVDNVKETLLPHPNPNTFSYLRNQPFSKRAFALLQNLFPILASLQNYNAQKLKCDLMAGLTLAIFAIPQCMGNATLARLSPEYGLYTGIVPPLIYAMLASSREIVIGPGSVDSLLLSSMIQTLKVPIHDSSTYIQLVFTVTFFAGIFQVAFGLFRFGFLVEHLSQATIVGFLAAAAVGIGLQQLKGLFGIDNFNNKTDLFSVVKSLWTSFKNQSAWHPYNLIIGFSFLCFILFTRFLGKRNKKLMWLSHVAPLLSVIGSSAIAYKINFNELQVKDYKVAVLGPIKGGSLNPSSLHQLTFDSQVVGHLIRIGLTIAIISLTGSIAVGRSFASLKGHSIDPNREVVSLGIMNIVGSLTSCYIASGSLSRTAVNYNAGSETMVSIIVMALTVLMSLKFLTGLLYFTPKAILAAIILSAVPGLIDLNKAREIWKVDKMDFLACTGAFLGVLFASVEIGLAIGCRSRYHLRR
What is the function of this protein?
Possible sulfate transporter.
What are the official names of this protein?
Early nodulin-70, N-70.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RIMM_AROAE
Sequence: MIVLGRIVAPFGVKGWVKVHPFGDDPLSWGEMPQWWLADDADAPESAWQPVTLAGFKEHGAGLVAAFVGHDDRNAAEALQGRFIGAPREALPKPDVDEYYWGDLIGLAVVNQADEALGTVEALMSTGAHDVLQVRDGDDERLIPFVAAYVLDVDLAARTIRVDWQKDW
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPRR2_STRCO
Sequence: MELEVRHLRALCAIADAGSLHRAARRLGVAQPTLSTQLTRIEQALGGPLFTRERTGCRPTPLGRTVLGRARPLLTDMNTLVREARAAAAGGDSRLRVGSTASRALAGWLRRLRRPGLEPTLQMDVSANALLRRVTDGQLDVAFVHEVEGCALHIPEDLRLRVLVEREPQFVMLPADHPAAARPVVRLADLADDRWMVDPTVDGEWDGVHRMLRAVGLNPRVLHGDYHTAASLVATGEVVTVCQPSSQSRPDTAVRRLYGDPLGVRLLLAARTRAELDAVFPALEDAYWEAARQSTAYREWLEGGGIRTLPRCPVAATGGGRVEFVRAR
What is the function of this protein?
Transcriptional trans-activator of the gene (mprA) for the small neutral protease.
What are the official names of this protein?
Small neutral protease regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: IHFA_ALKEH
Sequence: MALTKADMAERLFEEVGLNKREAKELVESFFEEIRQALEDGVPVKLSGFGNFDLRDKNERPGRNPKTGEEIPISARRVVTFRPGQKLKSRVEAYAGNVKQS
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.