PharMolix/UniProtQA huggingface dataset:
Protein: IF2_LEGPL
Sequence: MADVTVKQLAQVVGIPVERLLNQLQEAGLSFTDDQQTVNEEQKRILLNHLKGSSNRDISAAPERITLRRKSMSQVTVGHDMHSGKTVNIEVRKKKTFIKRSAIPEQAEVEEPVVPPVVEEPAHEEITVVSEVSADTSELKETEEHPVIEPVAALDETVKEEEKINSEENTAESQDELTHANTDVIENLVDVVEEAIPVSKKEEVKPEKVSKKKHLEQTDSDISEFKKGKKKPKYHTFEHDEEEQELHRRGGRSKFKKKKGTEKSDKYREAEETLTHGFALPTAPIVREVLIPETITVAELAKRMSVKAAEVIKVMMSLGAMATINQVIDQETSVIVVEEMGHKPVIIKEDAVETGLGEAISKGTKTEGRAPVVTIMGHVDHGKTSLLDYIRRTKVAAGEAGGITQHIGAYHVSTPKGDITFLDTPGHAAFTAMRARGAQATDIVILIVAADDGVKPQTIEAIQHAKAAKVPIIVAINKMDKPDADPERVMNELSVQEVIPEAWGGDTMFVNISAKSGMGIDDLLDAILLQSEVLELKAVTDGAAKGVVIESRLDKGRGPVATVLVQSGTLHKGDILLAGFQYGRVRALVSDNGDLVDSAGPSIPVEVLGLSAIPHAGDEAVVVPDEKKAREVALFRQGRFRDVKLARRQKTTIEGIMENMTATESKVLNIVLKADVQGSLEAISDALTKLSTDEVKVEVISSGVGGITESDVHLAIASNAILIGFNVRADGTAKRLAEQESVSIHYYSVIYDIVDQIKGALTGMLAPQFKEEIVGIAEVRDVFKSPKIGAIAGCMVIEGVVKRNNPIRVLRSNVVIYEGTLESLRRFKDDVLEVRQGFECGIGVKNYNDVKPGDLIEVFETVEIKRDL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_EHRRG
Sequence: MKIDLNTIFPSSCKEYIPGKIYKNIKIGMRKVSFNNDTESILIYDTGGPHSDQDIQTNINNGIKKLRVNWITDRQDVEYYDRHTINTNSSTAFPLQNNKALKSKNDKPVTQMFYAKNNIITPEMEYVAIRENSLIQKLLSHTPNTIIPEITPELVRQEVAAGRAIIPANINHPESEPMIIGKNFLVKINANIGNSAVSSDINNEVYKMIYAIIYGADTVMDLSTGSHIHNTREWIIRNSPVPIGTVPIYQALNKVNGIVGELNFNIFKETLIEQAEQGVDYFTIHAGVLKKYIQYTTNRLTGIVSRGGAIIAQWCSIHNKENFLYTNFEEICDIMKSYDIAFSLGDGLRPGSIADANDKAQFLELKTLGELTDIAWKHDCQVMIEGPGHVPMHLIKENVEKQMYFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTSMLCYVTPKEHLGLPNLNDVKNGVITYKIAAHAADLAKGNPSAYIRDYALSYARFNFRWYDQFNLSLDPETAKSFHDESLPSEHAKSAHFCSMCGPKFCSMKLTHQLQLNSTE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DP2L_METTP
Sequence: MSAEYFERLERGLREEMEIARRARSKGLDPETDVEIPIAVDLAERVEKLVSIPGVAERIREFEVQGLSREEAALAIGRDFAEGRLGKGASRLDAIDMAIRTSVALLTEGVVAAPIEGIARVGLGKNDDGSEYLKVYYAGPIRSAGGTAQALSVLVADYVRRSMGIAPYKPTDEEIERYVEEIGLYKRLQHLQYTPSDDEIRTIIRNCPVCIDGEPTEEEEVSGYRDLPRVETNRVRGGIALVSAEGIALKRPKIKKHVSKLGIDGWGWLDVLGGEKKDGGGSSGKFLRDLIAGRPVFSHPSRPGGFRLRYGRSRNTGLAAAGINPATMMVLNQFLAPGTQIKVEQPGKAAAVAPVSSIEGPTVRLTNGDVVRIDDPSSFPWISSPEALRRNISKIIDLGEILVSFGDFMENNRPLAPASYTFEWWAEEFRRAGGDPAGMEHVDGRTAIRLSRDFGVPLHPDHTYLWHDITLDELDLLADAASDGEIDGDALLMDMREDVKEVLEKLLVHHKVRDGMIVVEDALPLLLCLGVDETGRRWRREDLNADNALSAVNQLSGLVIRARAPTRIGCRMGRPEKSDRREMRPPPHVLFPTGSEGGKSRLVNEAAEHGFIEVVVERRRCPSCGKEGFAFRCECGAHTERVRACLSCGVRADDKCPRCGTETSAATRMRIDVKGTLARALESLGERVDNIRGVMGLTSRDSTPEPLEKGVLRAKHGVFIFKDGTSRYDLTDLPLTHFRPREIGTSVDALLDLGYTHDIHGKPLESDDQILELKVQDVVLCRNAGDWLLRVSKFIDDLLVKFYGLEPYYNAERPEDLIGRLMIGLAPHTSAGVLCRLIGFTRASAGYAHPYFHAAKRRNCDGDEDCVMLLMDALLNFSRSYLPEKRGGKMDAPLVLTTRINPAEVDKEAHNLDLSFIYPLEFYEATLRNANPKDVEGLIDLVSKRLGSEGQYCGFGFTHDTDDIAGGPRNSSYKTLETMIDKMKSQLELAKLIRAVDATDVAERVINSHFLPDLMGNLRAFSRQSVRCVKCNAKYRRPPLSESCPKCGGRLVLTVHEGSVRKYLEVSMKVAEEYGVSSYTRQRLELIQMEIESLFRSDKVKQTGLADFV
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II large subunit, Pol II, Exodeoxyribonuclease large subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal DNA polymerase II family.
Protein: CREB_ASPNC
Sequence: MGSFLRSFRRDVGSSTPSVGATPAKKEPLALPITPLEKMLQEMGSDSVRQDGSDKFFGMENYGNTCYCNSILQCLYYSVPFREAVLNYPTRTPIESLEAALAKNLRYQNFAANQEAEAQAEKQRLANAQRPGAPPAQPPKPEDKDSSEYKKKIALQSLPLLETKNNAGSYGMSESLFTSLKDIFESVVASQSRIGIVRPQHFLDVLRRENEMFRSAMHQDAHEFLNLVLNEVVANVEAEAMKQPIPSLPPADTTDSSRQSISSGSKTPNTTRWVHELFEGTLTSETQCLTCENVSQRDEIFLDLSVDLEQHSSVTSCLRKFSAEEMLCERNKFHCDNCGGLQEAEKRMKIKRLPRILALHLKRFKYTEDLQRLQKLFHRVVYPYHLRLFNTTDDAEDPDRLYELYAVVVHIGGGPYHGHYVSIIKTQDRGWLLFDDEMVEPVDKNYVRNFFGDKPGLACAYVLFYQETTLEAVLKEQEMENMNASAADANEAAVKPNGFPQPAGLAHVHSASQIPVQDEPQRHTGLRRAPTAPQLPTHTEYPGPDIEPSSPAVATPPPVPPIPETANRPLSPKKSDIQSKKERAKEEKERKAAEKEMEKQRRKEQEARVKENQRREEAELKAALEASKASKADEDRRNPTENGKDGDPKRSSNGLSRLKRGSKSFSQRLGKDKESRASSSGLPSVPSAEPLTPNPVPLEPVQQLSPRKASPPKESHVVHKPLGQDDEPDALKSPKGDRAGHGKWRSFSIRKKSFSILS
What is the function of this protein?
Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Deubiquitinates the creA catabolic repressor and the quinate permease qutD.  Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase creB, Carbon catabolite repression protein B, Deubiquitinating enzyme creB, Ubiquitin thioesterase creB, Ubiquitin-hydrolyzing enzyme creB, Ubiquitin-specific-processing protease creB.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: RS3_CALBD
Sequence: MGQKVHPKGFRLGIIRDWDSRWFANDKDFEKYVLEDYKIRRHIKEKLYNAGISRIEIERAAKRVKVIIHTAKPGIVIGRAGSGVEALRKELEKLTGGKTISLDIKEIKVPELDAQLVAENIAAQLEKRVSFRKAMKQAMARALRSGAKGIKTMVSGRLGGADIARTEWYKEGRIPLQTLRADIDYGFAEAHTTYGRIGVKTWIYKGDILPQKAAASEKGGDK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TRUD_ANADE
Sequence: MTDLPFVTADLPGSGGALRRAPEDFRVDEVPAYLPSGAGPHLYLRVEKRGRTTRDALRELARALGVPERDAGAAGLKDKDAVTTQWLSFPVARDPDPAALAAPGLRVLEVSRHQNKLRTGHVRANRFTLAVRGGDLARARDCAAALAARGLPNFFGPQRFGAAGRNAAVGRALVTGERSPEAGRAARDRFLRRLSLSAYQSLLFNRWLAERMADGRFAAALAGDVMKKLDTGGLFTCEDPATDGPRVERFEISPAGPMFGHALRLAGGEAGAREARLLEAEGIALADFVRGGGEAEGTRRAARLRIDVALEPLEDGYRAAFELPRGAYATVVMRELTKADAELPEED
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RL11_METEP
Sequence: MAKKITGYVKLQVPAGAANPSPPIGPALGQRGLNIMEFCKAFNAKTAQMEKGTPIPVIITAYQDRSFTFEMKQPPVTFFLKKAVGLKIGKKPASGSKTPGKGPTVGKITEAQLREIAEKKMPDLNCDSVDAAVAMIRGSARAMGLEVVA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DC2L1_BOVIN
Sequence: MPSETLWEIAKAEVEKRGSSENEGDGAEIGEKSVFFIGSKNGGKTTIILRCLDRDEPPKPTLALEYTYGRRTKGHNIPKDIAHFWELGGGTSLLDLISIPITSDTLRTFSIVLVLDLSKPNDLWPTMENLLQATKLNIDKVIMKLGKKNSKAASEMRQKMWSNMQKDHPDRELLDPFPIPLVIIGSKYDIFQDFDSEKRKVICKTLRFVAHYYGASLMFTSKSEALLLKIRGVINQLAFGINKSKSICVDQNKPLFITAGLDSLSQIGPPPLPDNDIGKLHARSPMDLWKKVYEKLFPPKSINTLKDVKDPAKDPQYAESEVDEMRIQKDQELEQYKRSSSKSWKQIELDS
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system, facilitating the assembly of these organelles.  Involved in the regulation of ciliary length.
What are the official names of this protein?
Cytoplasmic dynein 2 light intermediate chain 1.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the apical cytoplasm.
Protein: KDSB_MAGSA
Sequence: MAELTPIIVIPARMQATRLPGKPLADIHGEPMIIHVWRRSVQAGLGPVVVACSEAEVFDAVHAHGGQAVMTDPDHPSGSDRVWEAVRKLDPEGRFDAIVNVQGDLPTLDPQIIRAVFAPLAEPGVDVATLVTEITNEEERTNPNVVKAVVGLRPGQRVGRALYFSRATVPANAGPHYHHIGLYAYRRDSLERFVSLPQGVLESREKLEQLRALENGMRIDCALVDTVPLGVDTPADLERARALLKA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPA_ECO55
Sequence: MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: QUEF_YERPP
Sequence: MSSYQNHKALAELTLGKPTAYCDYYDATLLQAVPRSMNREPLGLYPDNLPFHGADIWTLYELSWLNSNGLPQVAVGEISLNADSINLIESKSFKLYLNSFNQTIFADKESVRMTLQRDLAACAQGNVSVALYDLDEITGQPISNFNGECLDKQDIRIDSYEFNADYLQGAAGKDHVEESLVSHLLKSNCLITHQPDWGSVQIHYRGPQIDHEALLRYLVSFRHHNEFHEQCVERIFNDIMRFCQPETLTVYARYTRRGGLDINPWRSNTDFVPLTGRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB3_MOUSE
Sequence: MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHVIEKDKITTRTLKARMD
What is the function of this protein?
Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit beta type-3, Proteasome chain 13, Proteasome component C10-II, Proteasome theta chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9.
Protein: TGT_RUMCH
Sequence: MAAVTYELIKTCKQTGARLGKVHTPHGSFDTPVFMPVGTLATVKGMSPEELKEIDARIILSNTYHCYLRPGQDIVKQAGGLHGFMNWDRPILTDSGGFQVFSLSGLRKITEEGVTFRSHLDGSKHVFTPESVMDIENDLGADIIMAFDECAPYPAEYDYVKKSMERTTRWAKRCKEAHTNTEKQSLFGIIQGGMYKELRIESANQLKELDFPGYAIGGLSVGEPAEIMYEVLDYTAPLMPADKPRYLMGVGTPDYLIEGAIRGIDMFDCVLPTRIGRNGTVLTSNGRVIIRDAKYSRDFSKLDPECDCYVCRNYSRAYIRHLIKCGELLGLRLTTWHNLYFLINLMKQVRQAIMDDKLASFRDEFYLKYGYTK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ANSME_KLEPN
Sequence: MLNIAALRQQQIPLAAEPRSPVPFHILMKPIGPACNLACRYCYYPQDETPVNKMDDARLEQFIRRYIAAQPAGAREINFVWQGGEPLLAGLSFYKKALALQARYAPDGVTISNSLQTNGTLINDAWCRLFREHGFIIGLGLEGNEALQDYHRPDKRGRSTWSAALRGIDLLHQHQVDFNLLVVVHNEMAAHAAAIYVRLVSLGARYLQFQPLMSEGAALREGYQLSADNWGRFMVGIWRQWRKRCDRGRVFVINIEQAWAQYFTHTSGSCVHSARCGSNLVMESDGQLYACDHLINTEHRLGRLDEQTLAAAVDASVQLPFGQQKSLRRECQTCSVKMVCQGGCPAHLNAAGNNRLCGGYYRFFSDILAPLRPFSRDLNGLKAWRAAFVGTAHTA
What is the function of this protein?
Involved in 'Ser-type' sulfatase maturation under anaerobic conditions.  Catalyzes the post-translational modification of serine ('Ser-72' in the arylsulfatase AtsA) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM) (PubMed:10336424, PubMed:12419807, PubMed:14749327, PubMed:18558715).  Is capable of catalyzing multiple turnovers (PubMed:18558715).  In vitro, use of a peptide substrate in which the target serine is changed to cysteine also gives rise to turnover, supporting approximately 4-fold the activity of that observed with the natural substrate (PubMed:18558715).
What are the official names of this protein?
Serine-type anaerobic sulfatase-maturating enzyme, Ser-type anaerobic sulfatase-maturating enzyme, Anaerobic sulfatase-maturating enzyme, AnSME, Arylsulfatase-activating protein, Formylglycine-generating enzyme.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRS29_ARATH
Sequence: MSIDSDVDPSEVSTAKRKPSRSWLLIDAAGNSTMLNVDSYAIIRRVHIYARDLRVFESSISSPLSIRTREGAIVLNLEHIKVIITADEVLLREPLNENVIPVAKEFERRLGVENRERRGQPDGKEDSGAEVDAEKDESPFEFRALEVALEAICSFLAARTTELEKSGYPALNELASKISNRNFGKVHKLKISMLTVRVQKVKDELQLWLEDDDDLGDLCLSRKIATTSSPVSDSDEQINSYPTSPTIGAKISRAKSHLVRSATVRGDDQNDVEEVEMLLEAHYMQIDRTLNKLAELREYLDDTEDYINFQLASSRNKLIEFEVIITAGSVCISVYSLVVGILSTNIPFSWNTKEHMFKWVVSATATLCAIFFVIIISYARYKKLVGN
What is the function of this protein?
Putative magnesium transporter.
What are the official names of this protein?
Putative magnesium transporter MRS2-9.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRPD_STRPI
Sequence: MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PYRE_SCHPO
Sequence: MSYKLELLRRALEHNVLKFGTFTLKSGRKSPYFFNSGNFTHGADLCALAEAYAETIIAMNVDFDVIFGPAYKGISLAAITAVKLYEKTGKSYGFAYNRKEAKSHGEGGNLVGAEMEGKKVLLLDDVITAGTAIREAISFLEPKHVKLAGIVLLLDRQERLDPEVNESTIGRLKKELNLPVSSILTLDDIVDFTKSDLTAAESKAMDAYRQQYQAK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RNH2_STAA9
Sequence: MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPITKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_STRA5
Sequence: MIDRKDTNRFKLVSKYSPSGDQPQAIETLVDNIEGGEKAQILKGATGTGKTYTMSQVIAQVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYADSVVSLRPGQEISRDQLLNNLVDIQFERNDIDFQRGKFRVRGDVVEVFPASRDEHAFRIEFFGDEIDRIREIESLTGRVLGEVEHLAIFPATHFMTNDEHMEEAISKIQAEMENQVELFEKEGKLIEAQRIRQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYEMEQTDTVVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRTEKGERTFITTLTKRMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSNGHVIMYADKITDSMQRAMDETARRRRLQMDYNEKHGIVPQTIKKEIRDLIAITKSNDSDKPEKVVDYSSLSKKERQAEIKALQQQMQEAAELLDFELAAQIRDVILELKAID
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_PASMU
Sequence: MKYELDKTDGNARRGRLVFERPQGTFTVETPAFMPVGTYGTVKGMTPEEVRATGAEILLGNTFHLWLRPGQEVMRKHGDLHDFMQWHRPILTDSGGFQVFSLGKLRKITEEGVKFQNPINGERIFLSPEKSMEIQYDLGSDIVMIFDECTPYPATFDYAKKSMEMSLRWAKRSRDRFDELGNKNALFGIIQGGVYEELRKVSVEGLVNIGFDGYAVGGLAVGEPKEDMHRILEYVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVSDGIVKIRNAKYREDTSPLDPECDCYTCKHYTKAYLYHLDKCGEILGARLNTIHNLRYYQRLMAQIRQAIEEDRFEAFVQEFYAKMGKPVPPMQSEIKSDEG
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PTR41_ARATH
Sequence: MANSDSGDKEAHRSSKHGGWITLPFMLVTLLGMSITYFGWVMNLIVFLIEEFNIKSIAAVQISNIVNGVVNMLPVVAAILADSFFGNIPVISASAFISLTGISLLTLIASLDYLRPRPCETGSILCQSPSKLQLGILYAALALVITGTAGTRFILASAGANQYKKPKEQGRFFNWYFFTLYGGAITGTTAIVYAQDNASWKLGFGLCVAANLISFIIFVAGKRLYEHDQPLGSPYTSLVRVLVAATMKRKAVISYKDEDYHHRELEKETKTYVAMPSKSFRFLNRAALKTEGDSNNNMWRLCSVQEVEDFKAVLRLVPLWTSVMFLSAPLAVQMSMTVLQAMVMDRKLGPHFKVSAGSMQVIALVSGCVFIILNNWTTYPMYQKLIRKPLTPLQKVGIGHVLTILSMAISAVVEAKRLKTVENSHLMSVLWLVPALVINGIGEAFHFPANIAIFYGEFPESLRNTATSLTSVVMGISFYLSTALIDVIQRTTKWLPNDINHGRVDNVYLVLVIIGVSNFGYFLVCSWFYKYRNLKNDDHEQDLKDVTN
What is the function of this protein?
Transporter involved in a passive nitrate efflux.
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 2.4, AtNPF2.4, Probable nitrate excretion transporter 5, Protein NAXT1-like 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.