PharMolix/UniProtQA huggingface dataset:
Protein: CYB5_ECTSH
Sequence: MNETEATLPVFTLEQVAEHHSPDDCWMAIHGKVYDLTPYVPNHPGPAGMMLVWCGQESTEAWETKSYGEPHSSLAARLLQRYLIGTLEEIT
What are the official names of this protein?
Soluble cytochrome b558.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
Protein: YPGR_BACSU
Sequence: MKIKSIEPTPSPNTMKVILTEELPAGKSNNYKPEQAEGAPLVIAEILKIDGVKGVYHVADFLAVERNARYDWKDILPQVRTAFGMESAESAEENRSDQESFGEVKVFVQMFSGIPMQVKLTDGEREERFGLPERFQQAILKLRSEASNVVFERAWKEQGVRFGDFDEIGHDVTEELQAAYSDERLKRLTEAAAQGKGEAKQAVQRKAYKVTLDMLDDEDWKKRYAHLEQMDPKEEDIPVLQKALDDPKVSIRRQAVVYLGMIETPDVLPLLYKALEDKAVSVRRTAGDCLSDIGDPQAIPAMIKSLSDSSKLVRWRAAMFLYEVGDESAIEALRAAEDDPEFEVSLQVKMALERIEHGEEAKGSVWKQMTESRKKGE
What are the official names of this protein?
Uncharacterized protein YpgR.
Protein: MURG_PROM3
Sequence: MPRLLIAASGTGGHLFPALAVAESLPASWSVCWLGVPDRLETQLVPERYELTTVRAGGLQGRGLRKLVQLLQLLAATGRVRKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESNAIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPVRSAFLSPQPLPHWVPCGDGPLLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDPDVGELDHPNLVEQPFSHEMPGLLQHADLAISRAGAGSLSELAVCGTPTILVPFPQAADQHQEANAACAAALGAAVIVHQHAAEHRALGHALEQLMGARLRGNAAASNPLIPMKQGMMKLAVREADQLLVTLLKPLIGAGL
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UBE2B_RAT
Sequence: MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1.  H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation (By similarity).  In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination.  Required for postreplication repair of UV-damaged DNA.  Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'.  May be involved in neurite outgrowth.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 B, E2 ubiquitin-conjugating enzyme B, RAD6 homolog B, HR6B, Ubiquitin carrier protein B, Ubiquitin-conjugating enzyme E2(14k), Ubiquitin-protein ligase B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Note=In peripheral neurons, expressed both at the plasma membrane and in nuclei.
Protein: ENDA_METKA
Sequence: MLCAGNGGKELPRAKVFEGGSLVSKDYEDLKRRYFGTEHGNVLFLDPFETVYLTEKGEIDPETPEGEPMSVEELLSFFERRRPGFRAGYVVYRDLTERGYVVKSGFKYGGRFRVYEEDPDREHSKYVVRVVEPDTELSTRDVLRATRLAHSVRKDFVLAVVEDVEEPRIEYVMWRWKRL
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: MCM3_ORYSJ
Sequence: MDVNEEAMAAHKRAFLDFLDQDVGKGVYMQAVRDMVQNKRHRLIIGMDDLRNHSLDLARRVIRSPAEYMQPASDAVTEVARNLDPKFLKEGQRVLVGFSGPFGFHRVTPRDLMSSFIGTMVCVEGIVTKCSLVRPKVVKSVHYCPATGGTLSREYRDITSFVGLPTGSVYPTRDENGNLLVTEYGMCEYKDHQTLSMQEVPENSAPGQLPRTVDIIVEDDLVDSCKPGDRVSIVGVYKALPGKSKGSVSGVFRTVLIANNVSLMNKEANAPVYTREDLKRMKEISRRNDTFDLLGNSLAPSIYGHLWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAVMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADRGVVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVIAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDPEIDRQISEHVARMHRYCTDDGGARSLDKTGYAEEDDGDVNAAIFVKYDRMLHGQDRRRGKKSKQDRLTVKFLKKYIHYAKNLIQPRLTDEASDHIATSYAELRDGGANAKSGGGTLPITARTLETIIRLSTAHAKMKLRHEVLKTDVEAALQVLNFAIYHKELTEMEEREQREMEMKQQADHDAGASGGNADEHRSSGNDPMDVDVGNASNDQDVPAERIEAFEAILGQHVLANHLDQISIDEIEQTVNREAAAPYNRRQVEFILERMQDANRIMIRDGIVRII
What is the function of this protein?
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.
What are the official names of this protein?
DNA replication licensing factor MCM3, Minichromosome maintenance protein 3, OsMCM3.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA_SYNS9
Sequence: MALGTTMTEAGEAALGRLRQWPGEHRVAVGLSGGVDSSLTAALLVEAGWEVEGLTLWLMSGKGACCAEGLVDAAGICEQLGIPHHVVDTRETFQKEIVQRLVDGYQDGITPLPCSQCNRSVKFGPMLEWAAQERNLPRIATGHYARIRHGGDCGRHQLLRGLDSRKDQSYFLYDLPQEALGRIVFPLGELTKADTRIEAGRHGLRTAEKPESQDLCLADHHGSMRAFLDTYLPPRQGEIVLKDGTVVGEHDGIEHFTIGQRKGLGVAWQEPLHVVKLDPAMNRVVVAPRAEAGRHEAVVGAINWVSIDPPLQAMNLEVQVRYRSAPVTARLTPLPATDDDHQRQRPHRCHLVFDEDQFSIAPGQAAVFYSDDTVLGGGLLQRDFDTNQE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP_SFAVA
Sequence: MSICYYDTVGREKRLLIINQRALALPNRTISSDGTCCDGDEYLLVDTFTKLNFKVQTIRNASKIVLETTVRNYIEKNVKRVACYFVVVLNDGNDADTILTTDGTYSLSELYALFTLYTVRAIPKVFLIQSCLGAKIDRSHCDRASCQCDQEEDAHPTSVCHDIFVNTVRRVIHACSRKSNGSTTTTETKCSDVATVVLTSPHTEETIIVYLRIEAYLRYGDTKCGCFMIEKFCKNLIKYGTRSSVHTTITMVQNEMQITDPKHVPIVQMNCTKLLFLGDENHIIMEEY
What is the function of this protein?
May induce host cell apoptosis and contribute of the establishment of a special cell cleavage process in which apoppotic bodies are rescued by the virus and differentiate to form large vesicles in which virion assembles.
What are the official names of this protein?
Executioner caspase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
Protein: KTHY_DEHM1
Sequence: MSLFITFEGGEGCGKSTQSKALYRYLKKLGLGCVLTHEPGGTRSGDKITRLLKWSEEENISPLAELFLFNASRSILIDNVIKPALLDGNIVICDRYTDSTLAYQGYGRGLELDTVKCINSLASGGLVPDLTIWLDMDDKAALLRKGKLPPDRFESENNGFHQRVRDGFGVIAAAEPNRFLKLDASLSQSELTKCIKQRVNALLKLPQ
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PANB_PROM9
Sequence: MLPSDLVKYKEQSQKIIALTAWDSISGSIAEQANVDLVLVGDSLAMVCLGYKSTLPLTLENIIYHTNAVSRGFKKKIEEQPLLVTDMPFLTYQCGEDKAVEYAGKIIQSTYAKAVKVEGAEPEIQKVISRLIRMGIPVMGHIGLTPQSYLNLGLKKQGESLESQEKIKKDASILEKLGCFSIVLEHMPELLAKEIQNNLTIPTIGIGAGNFCDGQVRVTADLLGLNDDQPPFCQPIIQGKHLFKDKLKEWVDSERLN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_STRR6
Sequence: MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDCLQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREISSQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLVETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTGQDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ZO29_XENLA
Sequence: MGMSEKASDTGMKGKKKDKNERNEKILNLTLEMIYLLTGEGYVIPKKKKSGDDMAPPQSCTDCILEGGCRCHVTNLTGGRALHAPGSVIQKENNKNDKKILELVSNIIQLLTGEEWEYIKRKKALYMEGIKEDPQQLSQWCEYEDKSIVMCNLEATACLNNDPRNDTVFCEHRDLSKFDTSLAEQSLPAIGIKGEPVSCEGANQSDCNINPLAEQIQGTDTPTPIMGCSLNNSLSDNYISNGIKTEATSCEAGNQSDYGNNPVAEVQLTDTTTPVKRCSLNSILSDNYIKIAIKEEPPSWEDENQTHCSINAPGEQNEEIDTPTSIMRFCLNSSLLDSSLLNAIKDDTLSCEGENYSDCSFNPLTEQTSPGCKQFTCSECGKTYTRLYNLKIHLKSHTDDKTFSCSECEECFTDHTDLVIHRRLHLTLKAFPCAECGKCFTNCTNLRAHSKTHTGEKPYSCTECGKTFRDRSHLNIHKKRHTGEKPYTCSECGKCFAYRSNLMVHVRIHTGEKPFSCSKCGKCFTDHANLIVHERMH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Oocyte zinc finger protein XlCOF29.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBC39_ARATH
Sequence: MVEIKDSSNVRKLKEEFLRDFKRFDTVEDFSDHHYAAEGSPAKLSLWHLKFKGRPKNWVKDIQKEWKILDKNLPETIFVRACESRIDLLRAVIIGAEGTPYHDGLFFFDIQFPDTYPSVPPKVHYHSGGLRINPNLYKCGKVCLSLISTWTGKKREKWLPKESTMLQLLVSIQALILNEKPYYNEPGYEKSMGTPLGESYSKDYSENVFVFSLKTMHFEEFVRSHFFVRSHDIVKACNAYKDGAPVGSIDKGGVKKQTRQRGSLKFRINVTSFMKTVVDEFVNLGAIREANHRGEPNPTLFSCFFFCYLELIICSV
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Putative ubiquitin-conjugating enzyme E2 39, E2 ubiquitin-conjugating enzyme 39, Ubiquitin carrier protein 39.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: CBPM_COXBR
Sequence: MTKQIIKGIIIERSSPLKIDELSQAVHLRREIIIEMVEHRLIEPEGSSPTSWKFDNVCLKRAKIAASFYRDLEINMPGIAIALDLLDKIEHLEQRLRTLERFENQE
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: Y2922_MYCBO
Sequence: MTTLKTMTRVQLGAMGEALAVDYLTSMGLRILNRNWRCRYGELDVIACDAATRTVVFVEVKTRTGDGYGGLAHAVTERKVRRLRRLAGLWLADQEERWAAVRIDVIGVRVGPKNSGRTPELTHLQGIG
What are the official names of this protein?
UPF0102 protein Mb2922c.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: DUS3_VANPO
Sequence: MSAEKRELEDSGSNGELKRQDVSFSKGIAHIKAEFIAKSNDNSQFQQAYNDEEIADADRIGAEGGKNSRKHKKKQRGQNKSRDNRQVKEEKVLCPKYIQGYSEDGESLCQFGDKCRFVHDIKEYLSHKKPEIELDQFKICPVFDALGFCPMGFKCRFMSSHFDKENFKLVKRGTDEERQKLWSLDHEVNRITSEEKLSLIKRRFPFTKSNEVLDIIDSIQQEFRDITAPKVSKEEASEDKPKDSNEAEVAPQVLQREEELKKKREHQRELYLKYKDTRYFAQEKKDLDLRRKKIVSPLTTVGNLPYRRLMRKLGADVTYSEMALAVPLIQGTNSEWALPKAHSTEIPGFGVQIACSKAWQAAKAAEALAKFTPDINEINLNSGCPIDLLYRQGSGSALLDNPARMIRCLNAMNYVSDSIPITVKIRTGTRDSHPVADTLVKRLVYETDVAAITLHGRSRQQRYTRVADWDYVSTVAKSLRESEASFLESAEGKESRESKRRIQFVGNGDVNNFEDWHRILNNDENIDSIMVARGALIKPWVFEEVDAQQHLDKSSTERLEILRDYAQFSMEHWGTDEYGIAQCRRFFCEFMSFFHRYIPIGICERYPVQLNERPPNWVGRDDLETLMGSTDARDWIKLSEMFFGKVEESFVFTPKHKSSSFPSA
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SGD_PSEPU
Sequence: MSEKHKKIEELRSQRWFAPDTIRAFAHRQRLQQIGLRREEFMGKPVIAILNTWSEMSPCHSHLRDRAEAVKRGVWAAGGFPVELPVQSVGEVMVKPTTMLYRNLLAMEAEELLRSLPIDGAVLLGGCDKSTPGLLMGALSMDLPVIYCPAGPMSNGQWRGVKTGAGTHTKKYWDERRLGLIDTVAWEELEGAMTRSIGTCNTVGTASTMTSIADAMGFTLPGASSIPAADGAHPRMASQCGSAIVDLVWRDRRPSTWLTDKHVANGVAVYMAMGGSTNAAIHLIAIARRAGIDLTLDQLAAAAAKIPVLLNLFPSGTALMEDYHFAGGLRALMRKIEPHLHLECEGATGQSWDSLLADAPCYDDDIIRSLDNPVVSLEQGATLALLRGNLCPDGAVMKSSAAEPRLRRHSGPALVFDDHETLSRMIDDPALEVTADTVLILRNAGPVGAPGMPEWGNLPIPKRLLEAGVRDLLRISDSRMSGTHYGSCVLHVAPEAAVGGPLALVRTGDIIDLDVAAGTLNMRVSDDELARRRAGHVPQHKTYGRSFAALYQQHVTQANEGCDFDFLQAGEAVPEPPIH
What is the function of this protein?
Catalyzes the dehydration of 6-deoxy-6-sulfo-D-gluconate to 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate.  Is involved in a degradation pathway of sulfoquinovose (SQ) that allows P. putida SQ1 to use SQ as the sole carbon and energy source for growth.
What are the official names of this protein?
6-deoxy-6-sulfo-D-gluconate dehydratase, SG dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RL19_BORPA
Sequence: MNLIAILEQEEIARLTGGNAVTEFAPGDTVVVSVNVVEGTRKRVQAFEGVVIAKRNRGLNSSFIVRKISSGEAVERTFQLYSPQIAGIEVKRRGDVRRAKLYYLRSRSGKSARIKEKLVLKKAKSA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: COXX_METS4
Sequence: MTSLTNSLNPARSLAPASNGDVADFFALLKPRVMALVIFTALVGMTVTKSHVNPVIAAVSLLMIAVGAGASGCLNMWWDADVDAVMSRTRTRPIPAGKIRPDEALAFGMTLSVGSVLMLGLAANWLAAGLLAFTIAFYAVIYSMWLKRATAQNIVIGGAAGALPPMIGQAVVTGTVGIEGLVLFLIIFVWTPPHFWALALVKSGDYAKAGIPMMPNVAGPDSTRRQIVAYTLLLAPLGLAPVALGFGGLIYGLVALLGGLAMLALSLQVYHRREGEGADKAAMGLFGFSILYLFLLFSALLAEQGLGLFRPVSQLFG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTK1_SCHPO
Sequence: MSYSKSTIYRRQGTEPNSHFRRTVEEKSQLSGTNEESLGGHTLSSNAFKNNSSSISPSSSAKDPREQRKRTFPLNDTHSSRARQHERPFRSRKSRRRKGKKAFSPRPGSPPSPSFYRSGSQKRARNLTTKDYFAKRSESSSSASVSPISPSANRNDSKRQASSFRRSPPSSVHMKPSAFNGRKVSRRPSSSPPPIPSIPHETTSSDTQKKSSVSSGFPENKHGKFHFHIPNERRSRFDQPPSKRMALTSTARESVPAPLPSPPSGPIYTYTYPKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNIVRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPEVKNLPWYELLKPVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYFTSESPPPEPAVILKNMQGSWHEWESKKRKSKR
What is the function of this protein?
Catalytic subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit.  Involved in RNA polymerase II transcriptional elongation and pre-mRNA 3'-end processing (By similarity).  Together with ctk2/lsc1, required for the regulation of cytokinesis by phosphorylating 'Ser-2' residues found in the heptad repeats of the CTD.  Required for nuclear localization of ctk2/lsc1.  Positively regulates the septation initiation network (SIN) and promotes successful completion of cytokinesis in response to perturbation of the actomyosin ring.  Acts in parallel to clp1 to promote actomyosin ring stability upon cytokinesis checkpoint activation.
What are the official names of this protein?
CTD kinase subunit alpha, CTDK-I subunit alpha, CTD kinase subunit 1, Latrunculin sensitive kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Localized to nucleus during all cell cycle phases.
Protein: IF3_COREF
Sequence: MNGFLVCQRGNFLKWYGTSSFSRTANRGVHISAEARINERIRVPEVRLVGPNGEQVGIVRIEDARKLAFDADLDLVEVAPTAKPPVCKIMDYGKFKYEAAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKSNVIRFLEKGSKVKVTIMFRGREQARPELGYRLLERLANDVAEYGVVETRAKQDGRNMTMVIGPLRKGKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_LISMC
Sequence: MTKSVTVKDLKERLNLELICSETGLERPISTSDLSRPGLELTGFFSYYPEDRVQLFGMTEISFSEGMEPEERLKRYKQMCTKRTPAFVISRNLEVPKELVAAAKEADIPVLRSRLKTTRLSVYITNYLESRLAPVISMHGVLVDIYGLGVLITGSSGVGKSETALELVKRGHRLVADDNVEIRQEDEMTLIGSSPAIIEHLLEIRGLGIINVMTLFGAGAVRSSKKITIVVHLENWDPDKHYDRVGLDQEKTKIFDMDIPKITVPVRPGRNLSVIIEVAAMNFRLKNMGYNAAEQFTQDLNNLIGHNSSMND
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: PURA_SYNE7
Sequence: MANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTVVVGEQTLKLHLIPSGILYPDTQCIIGSGTVIDPKVLLGEVEMLEQLGISTDHLLISQTAHVTMPYHRLIDQASEQQRGSHKIGTTGRGIGPTYADKSERTGIRILDLMDPEGLREQLTWTIAQKNVILDKLYGLPPLDAESVIEEYSGYAERLRPHVVDSSLTIDEAWRKRKNILFEGAQGTLLDLDHGTYPYVTSSNPVAGGACIGAGVGPTIIDRVIGVAKAYTTRVGEGPFPTELHGDIGELLCQRGAEFGTTTGRRRRCGWFDAVIGRYAVRINGIDCLAITKLDVLDDLDEIQVCVAYDIDGERCDHFPSSARSFANCQPIYKTVPGWKQSTSHCRNLEDLPKAALDYLKFLAELMEVPIAIVSLGASRDQTIIVEDPIHGPKRALLYTNGDSSAS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_ACIAC
Sequence: MATKGGRDKIKLESTAGTGHFYTTTKNKKTMPEKMSIIKFDPKARKHVEYKEMKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CYSH_GEOTN
Sequence: MLTYDRWETVEKPSFPSDNETKGALDVLAWAYREYGDEIVYACSFGIEGIVLIDLISQVKPDAEIVFLDTGLHFQETYDTIAKVKETYPSLRIIMKQPHLTLEEQAAQFGDELWKRDPNKCCELRKVIPLREVLTGVTAWISGLRREQSPTRRHVEYVNKDDKFRSIKVCPLIHWTWKDVWNYVYKHSLPYNVLHDRGYPSIGCAPCTAPALDPNDLRSGRWAGQGKTECGLHLT
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRD1_YEAST
Sequence: MQQDDDFQNFVATLESFKDLKSGISGSRIKKLTTYALDHIDIESKIISLIIDYSRLCPDSHKLGSLYIIDSIGRAYLDETRSNSNSSSNKPGTCAHAINTLGEVIQELLSDAIAKSNQDHKEKIRMLLDIWDRSGLFQKSYLNAIRSKCFAMDISNNTANTASQQLSLDPKQRSKQILSNLKKSPPLNLNISLPTDLTSTDPAKQQAALFQVIAALQKHFKTLPSHTSVGTVAPPQAHTITEYGSRRERERERERYNSRRNRSRSPPAPFSQPSTGRKDRYPSVAQDQYSIGAPNTTFGTNNHHLYPDELNVSNNPHYRPKPVSYDSTLPPDHIKVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSVILNNSRKHAFVKVYSRHEAENVLQNFNKDGALPLRTRWGVGFGPRDCCDYQHGYSIIPMHRLTDADKKWSVSAQWGGTSGQPLVTGIVFEEPDIIVGEGVSSKAISQKMPTDSGRNGPRSGKPNKSGSISSISPVPYGNAPLASPPPQQYVQPMMQQPYGYAPNQPLPSQGPAAAAPPVPQQQFDPTAQLNSLMNMLNQQQQQQQQS
What is the function of this protein?
Plays a role in sequence-specific regulation of nuclear pre-mRNA abundance.
What are the official names of this protein?
Protein NRD1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLSA_PSEF5
Sequence: MDYFGPHIFGYLIALLHFLGLIAAIHAVLTVRTAQGAIAWALSLLFMPYLTLIPYLVFGRSTFDAYIQARRQANVEMHKAINELNWRPWVEEALTARASKAYASLRAMPKLGRMPCLANNQVRLLVNGDATFEAIFNAIRRSHKAVLIQFFIIHDDDLGRRLQRLLLEKAAEGVSIHLLYDRIGSHSLPASYVQTLRDAGVQVHAFATRSGWLNRFQVNFRNHRKIVVVDGMLGFVGGHNVGDEYLGKKPPLAPWRDTHVQVSGPVVACLQESFAEDWFWAARELPPLILPDTYPDDGVLCQLLASGPADAYETCSLFFVEAIHAATERVWITSPYFIPDEAVFAALRLAVLRDVDVRILLPARPDHRIVYAASSLYAFEAVRAGVRVFRYQPGFLHQKVVLIDNEISAIGSANLDNRSFRLNFEVMLLTVDDDFATEVEHMLEADFAKAREIAKEESRQTHRLQQLGMRVARLISPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDHN_SYNJB
Sequence: MLLVGSGAKFVQQLEQAGALAIYVTPEGGSEGHYLRRLRGAGYEVVTLSSKGIGDLASYLTRIHGVRPATLGKSERRTYFFPALIEQYRATLPPKAKGLVFWFYEGHVFSQQELSYLVKLSREDKGVKFVVELGRERSIRWQPLQSA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit N, NAD(P)H dehydrogenase I subunit N, NDH-1 subunit N, NDH-N.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhN subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.