PharMolix/UniProtQA huggingface dataset:
Protein: RS4_FERNB
Sequence: MARNTGPLCKLCRREGMKLYLKGERCFSEKCPFDKRPFAPGQHGREKKKLTQYALQLRAKQTMKRIYGVLEKQFRIYYERAVKQSGDTRENLVAQVERRLDNVVYRLGFAINRRAARQLVSHGHVLVNGKKVDIPSYQVRPGDVISIKEGSRTIEPIKQAIELNKGRAISNWLEVDYDQFKGVYVRNPKLEEIIDLPVNVQAIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: AROC_SINMW
Sequence: MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGLRFTLADIQTWLDKRKPGQSRFVTQRREDDLVKVLSGVMLDDDGETMISTGTPISMLIENTDQRSKDYSEIAKRYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGAIARQVVPGLVVRGALVQIGKHRIDRANWDWAEVGKNPFFSPDPAVVPVWEEYLDGIRKAGSSIGAIVEVIAEGVPAGIGAPIYGKLDQDIAANLMSINAVKGVEIGNGFAAAEISGEDNADEMRVGAGGDAVFLSNNAGGILGGISTGQPVVARFAIKPTSSILSERRSIDSDGKEVDVRTKGRHDPCVGIRAVPIGEAMLACAIADHYLRDRGQTGRLK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HPRK_STACT
Sequence: MLTARALVNKFNLQLVAGEEGLDRPIHNTDISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDEERHGRLRKLCRPDTPAIIVTRDIEPPEELVVAAKELGTPLLTSKDATTSLMSRLTTYLEHELAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIREITKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKKIGLNINLENWDKNKLYDRVGLNEETLRILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFNERLNAEILRKNEHKEENES
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: BSUHB_THEMA
Sequence: MDRLDFSIKLLRKVGHLLMIHWGRVDNVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPDENIMAEEGIFEKGDRLWIIDPIDGTINFVHGLPNFSISLAYVENGEVKLGVVHAPALNETLYAEEGSGAFFNGERIRVSENASLEECVGSTGSYVDFTGKFIERMEKRTRRIRILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEAGGMVTDFSGKEANAFSKNFIFSNGLIHDEVVKVVNEVVEEIGGK
What is the function of this protein?
Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P) but displaying a 20-fold higher rate of hydrolysis of D-I-1-P than of the L isomer, 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate.  Cannot hydrolyze glucose-6-phosphate, fructose-6-phosphate, 5'-AMP and NAD(+).  May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.
What are the official names of this protein?
Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, FBPase/IMPase, Inositol-1-phosphatase, I-1-Pase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily. FBPase class 4 family.
Protein: SIZ1_ARATH
Sequence: MDLEANCKEKLSYFRIKELKDVLTQLGLSKQGKKQELVDRILTLLSDEQAARLLSKKNTVAKEAVAKLVDDTYRKMQVSGASDLASKGQVSSDTSNLKVKGEPEDPFQPEIKVRCVCGNSLETDSMIQCEDPRCHVWQHVGCVILPDKPMDGNPPLPESFYCEICRLTRADPFWVTVAHPLSPVRLTATTIPNDGASTMQSVERTFQITRADKDLLAKPEYDVQAWCMLLNDKVLFRMQWPQYADLQVNGVPVRAINRPGGQLLGVNGRDDGPIITSCIRDGVNRISLSGGDVRIFCFGVRLVKRRTLQQVLNLIPEEGKGETFEDALARVRRCIGGGGGDDNADSDSDIEVVADFFGVNLRCPMSGSRIKVAGRFLPCVHMGCFDLDVFVELNQRSRKWQCPICLKNYSVEHVIVDPYFNRITSKMKHCDEEVTEIEVKPDGSWRVKFKRESERRELGELSQWHAPDGSLCPSAVDIKRKMEMLPVKQEGYSDGPAPLKLGIRKNRNGIWEVSKPNTNGLSSSNRQEKVGYQEKNIIPMSSSATGSGRDGDDASVNQDAIGTFDFVANGMELDSISMNVDSGYNFPDRNQSGEGGNNEVIVLSDSDDENDLVITPGPAYSGCQTDGGLTFPLNPPGIINSYNEDPHSIAGGSSGLGLFNDDDEFDTPLWSFPSETPEAPGFQLFRSDADVSGGLVGLHHHSPLNCSPEINGGYTMAPETSMASVPVVPGSTGRSEANDGLVDNPLAFGRDDPSLQIFLPTKPDASAQSGFKNQADMSNGLRSEDWISLRLGDSASGNHGDPATTNGINSSHQMSTREGSMDTTTETASLLLGMNDSRQDKAKKQRSDNPFSFPRQKRSNNEQDHQTRHRSLNKICIILCAGKN
What is the function of this protein?
E3 SUMO protein ligase involved in regulation processes.  Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses (PubMed:15894620).  Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling.  Probably not involved in jasmonic acid (JA)-mediated defense response.  Participates in abiotic stress-induced sumoylation.  Controls heat shock-induced SUMO1 and SUMO2 conjugation and facilitates basal thermotolerance.  Involved in freezing tolerance by mediating sumoylation of ICE1, a transcription activator of the cold signaling regulator CBF3/DREB1A.  Acts as positive regulator of drought stress tolerance.  Acts as floral repressor that promotes FLC expression by repressing FLD activity through sumoylation.  Acts as negative regulator of abscisic acid (ABA) signaling through ABI5 sumoylation.  Mediates sumoylation of SCE1, GTE3 and GTE5.  Functions as negative regulator of SnRK1 signaling through sumoylation of several components of the SnRK1 complex (PubMed:26662259).
What are the official names of this protein?
E3 SUMO-protein ligase SIZ1, E3 SUMO-protein transferase SIZ1.
What is the protein family that this protein belongs to?
Belongs to the PIAS family.
Protein: CYOA_PSEAE
Sequence: MTKANPFAALKWLSLAPALLLGGCDMTLFNPKGQVGMDERTLIITATLLMLIVVIPVIVMTLAFAWKYRASNTQAEYKPDWHHSNRIEAVVWLVPCVIIAILGWITWESTHKLDPYRPLDSEVKPVTIQAVSLDWKWLFIYPEQGIATVNEIAFPKDTPVNFQITSDSVMNSFFIPQLGSQIYSMAGMMTKLHLIANEEGVFDGISANYSGGGFSGMRFKAIATSEQGFQDWVAKVKAAPASLSIGTYPELVKPSENVPPTYFSSVSPELFGHILTKYEHHGDAKGAAHGEHAGAEHEAAMTGHDMQDMDMQAMQGMKDMKDMHMQPSTQE
What is the function of this protein?
Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration.  Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity).
What are the official names of this protein?
Cytochrome bo(3) ubiquinol oxidase subunit 2, Cytochrome o ubiquinol oxidase subunit 2, Cytochrome o subunit 2, Oxidase bo(3) subunit 2, Ubiquinol oxidase polypeptide II, Ubiquinol oxidase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BAR6_CHITE
Sequence: EKKRPDDNDDNDDEDRPERPERPEEPERPERPERPERPEEPEREEPEREPKCDDEMREKVKRRCDNENRRFDARRCECGEKKRPDDNDDNDDEDRPERPERPERPERPERPERPEEPEREEPEREPKCDEEMREKFKRRCDNENRRFDARRCECGEKKRPDDNDDEDRPERPERPERPERPEEPEREEPEREPKCDDEMREKVKRRCDNENRRFDARRCECGEKKRPDDNDDEDR
What is the function of this protein?
Used by the larvae to construct a supramolecular structure, the larval tube.
What are the official names of this protein?
Balbiani ring protein 6, Giant secretory protein I-C, GSP-IC.
What are the subcellular locations of this protein?
Secreted.
Protein: VIRBB_BARHE
Sequence: MNQNLHTLSDETVAIVLTKLEPISTFLKDENLFEIVINRPYQVMTEGVEGWKTIETPALSFNELMGIAKVVASYSKQNISEKNPILSATLPGNERIQIVIPPAVEKNTISMTIRKPSSRSFSLEDLANKGLFSVCEQVSFTPLNNYLSHLSELKHIDHDLVRAYAKKDFVFFLNQAVQCQKNILIAGKTGSGKTTLSKALIAKIPDDERIITIEDTPELVVPQPNYVSMIYSKDGQGLASVGPKELLESALRMRPDRILLQELRDGTAFYYIRNVNSGHPGSITTVHASTALAAFEQMTLLVKESEGGGDLERDDIRGLLISMIDIIIQCKRIEGKFKVTEIYYDPFKQRNIFGGN
What is the function of this protein?
The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function.  VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a pro-inflammatory activation by nuclear factor NF-kappa-B, inhibition of early and late events of apoptosis, leading to an increased cell survival, and, at high infection doses, a cytostatic or cytotoxic effect, which interfers with a potent VirB-independent mitogenic activity.  These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G.  Altogether with VirB4, may be implicated in providing the energy, via hydrolysis of ATP, for the assembly of secretion system and substrate transport.
What are the official names of this protein?
Type IV secretion system protein VirB11.
What is the protein family that this protein belongs to?
Belongs to the GSP E family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: F16PA_PARDP
Sequence: MTAETIQTDRIPPHLRPAMQALAEAGARLAAIIRRGGDLAQPVGTNADGDGQKALDVIADDLFCQTLAGAGVRWLASEEQEQAVALDPEGTLAVAIDPLDGSSNIDTNVSIGTIFSIYPAEATAEASFLRPARQQIGAGYIIYGPRCAMMVTFGDGVQHYALDPEDDAFRLVATRRQMPDCALEFAINASNYRHWPQPIRAYIDDCLAGSDGPREQNFNMRWIASLVAETHRILVRGGVFLYPSDARKGYEHGRLRMLYECAPIAFLIEQAGGGATDGRTAILEQGAPTLHQRTPFVFGSAEKVARIAAYHELPETEVSALFGHRGLFRA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_HAEIN
Sequence: MTALFQQLPSVDKILKTPQGLQLITEFGHTAVVATCRELLTQARQFIKKNNQLPEYFSNFDRTFLEIHSHLQKQNQVQIKAVHNLTGTVLHTNLGRALWSEAAQQAALSAMQKNVSLEYDLDEGKRSHRDNYISELLCKLTGAEAACIVNNNAAAVLLMLATFAQGKEVIISRGELIEIGGAFRIPDIMEQAGCHLVEVGTTNRTHLKDYRNAITENTAFLMKVHSSNYQICGFTSSVSEEELTELGQEMNVPVVTDLGSGALVDLSQYGLPKEPTVQEKIAQGVDLVSFSGDKLLGGVQAGIIVGKKEWIEQLQAHPLKRVLRCDKVILAGLEATLRLYLNPEKLTEKLPTLRLLTQPLKQLKINAMRLKERLESRLNSQFELQIEASQAQIGSGSQPMERIPSVAVTIAEKTNAKLSALSARFKQLSQPIIGRMENGKIWLDLRSLADIETLLNTLDEL
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_THESM
Sequence: MGIFIVLEGIDGAGKSTQAKMLAKWFENRGYEVVLTKEPTDTAFGKLIRRLVLIGGKEGIIDGARISKEAEALLFAADRAEHVKKLIEPSIKAGKVVISDRYFYSSLAYQWARGLDLNWLINLNAFAPRADLVILLDLPVKESINRINGRSIRSEFDKIVELQKKVRKNYLKLAEKFNEIRIINALAPVEDIHNDITALIEHELFEKAED
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PPIC_ECO57
Sequence: MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase C, PPIase C, Parvulin, Rotamase C.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTRC_METJA
Sequence: MSHGGGGHAAELYPEEQIFAVGIALSLVGCYLANFLSPYGLGMLIGGLLASAACVAGANTVRKVAAYGLGTGVPSIGMVSLGMGTLAAVAGVLIPDYFNLPYLVAPIITLIVSAVIGYIVGRLTVNPVGMKIPIMVRSMTFLSIAGAMALLGFTVAYVGSLEPQKYIDYALNNGMMALAFIAAGMAILHPFNACLGPNESHKRTLTLAVACGFITWFVFSVVKLDIVSIIVSIILWAIVYVKFVKMSFKDACAVLHVPEIPKKEE
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit C, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C.
What is the protein family that this protein belongs to?
Belongs to the MtrC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS1_DESAL
Sequence: MTDTLKLGVPKGSLQNATIELFKRSGWKINVHSRNYFPDINDAEINCAICRAQEMSIYVENGTLDAGLTGKDWIAENQSDVHVVTDLVYSKVSSRPARWVLAVAGDSPVKTLEDLQGAKIATEMVGFTKRYFAERGIDVEVEFSWGATEAKVVSGLADAIVEVTETESTIRAHGLRIIKELMQTNTQLIANKKAWEDPFKQKKINQLAMMLKSALVAETLVGLKMNVPEEKADDVIAILPSLNAPTVSHLYKSTWLSVEIVVDVSVVRDLIPQLLEKGAEGIVEYSLNKVMF
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMM3_ECOLX
Sequence: MGLKLDLTWFDKSTEDFKGEEYSKDFGDDGSVMESLGVPFKDNVNNGCFDVIAEWVPLLQPYFNHQIDISDNEYFVSFDYRDGDW
What is the function of this protein?
This protein inhibits the 16S RNA hydrolyzing activity of colicin E3 by binding with high affinity to the C-terminal catalytic domain of E3.  This protein is able to protect a cell, which harbors the plasmid ColE3 against colicin E3.
What are the official names of this protein?
Colicin-E3 immunity protein, Colicin-E3 chain B, ImmE3, Microcin-E3 immunity protein.
What is the protein family that this protein belongs to?
Belongs to the cloacin immunity protein family.
Protein: CEPT1_HUMAN
Sequence: MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIPVLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAAMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKVSTAHSNHH
What is the function of this protein?
Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively.  Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface.  Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.
What are the official names of this protein?
Choline/ethanolaminephosphotransferase 1, hCEPT1, 1-alkenyl-2-acylglycerol choline phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: PTH_RHILO
Sequence: MLVFAGLGNPGAKYADNRHNVGFMAADAIARRHSFSPWSKKFQGLIAEGTIAGEKIILIKPQTFMNLSGQSVGEALRFYKLELSALTVFYDEIDLAEGKLRIKTGGGAGGHNGIRSIDGHIGNAYRRVRIGVGHPGIKEMVQHHVLGDFAKADREWLDPLLDAIADNAAMIVKGDESGFMNKAALAVQGKAIAELEKPAQKQQPKQQSHIRQARSQQAPAKLPETGPMAAMLKKLFGNKD
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_SHEHH
Sequence: METVISFTAIAVAIMIGLAALGTGIGFAILGGKFLEASARQPELAPALQTKMFIVAGLLDAISMIAVGVALFFVFANPFLGQLAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBFA_RICFE
Sequence: MKKLTKTNSHRQQKLASIINEALIEILRRGKMLDSRLFDCPLTITKVIVTADLKIANCYFLPFNTKLTIDEIMDALSNSKNAIRNFITNKINMKFSPDIRFHYDHGFDNAIKVEELLKNI
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CENPT_CHICK
Sequence: MDGRVGLRASRRAAPTPRVAVRSSPRHRARVREQEPVVSAMSGSGLGKENKAGSSTPLRHRPNAFSELDNATPRVMLRKIIQNQPQVSPLALQTVQLEETEDARPEPPSQRTSSTVELQLPDLVPEDASVTTFRMTRKRKKLSISEFERAADKRLPQNQAHSTLDSTLVRSLRMSVGSVMAPDTVEKRGLLRRPQNHKAIDIAAFEGGVEQNMLQIKAQDYLVDLQTSSMTGTTTIRTDAEVVLNNTELFVEPQLGEQNLLAVEPQLSDSKTSAQRSNTSYPAHEKARLEGLVSRVSTDERRTLRFSEKDLITDHEHVDGITQKTPAKQGEEEQDHSQQNDPMEQFSESEEMAGTTEHHADAEYSEHSEKKLSRKAVSQLTAAQDAGVEMEMTPSEGGVAEGTEHQDSPKAELQMAGSPGGHSPASYSLEKPGAKPLKEAVEQTGEIERGTITGVLDAAEEEATDDESDKEDHESEEISMKTPMFVHAAAYRPQPVLSPPHPVKSASPELPPQPVRAKPVPKSSGAAQRKTREPEIASSLIKQIFSHYVKTPVTRDAYKIVEKCSERYFKQISSDLEAYSQHAGRKTVEMADVELLMRRQGLVTDKMPLHVLVERHLPLEYRKLLIPIAVSGNKVIPCK
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity).  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity).  Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA.  Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly.  CENPT has a fundamental role in kinetochore assembly and function.  It is one of the inner kinetochore proteins, with most further proteins binding downstream.  Required for normal chromosome organization and normal progress through mitosis.
What are the official names of this protein?
Centromere protein T, CENP-T.
What is the protein family that this protein belongs to?
Belongs to the CENP-T/CNN1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus.
Protein: XYLR_PSEPU
Sequence: MSLTYKPKMQHEDMQDLSSQIRFVAAEGKIWLGEQRMLVMQLSTLASFRREIISLIGVERAKGFFLRLGYQSGLMDAELARKLRPAMREEEVFLAGPQLYALKGMVKVRLLTMDIAIRDGRFNVEAEWIDSFEVDICRTELGLMNEPVCWTVLGYASGYGSAFMGRRIIFQETSCRGCGDDKCLIVGKTAEEWGDVSSFEAYFKSDPIVDERYELQTQVANLRNRLKQYDGQYYGIGHSPAYKRICETIDKAARGRVSVLLLGETGVGKEVIARSVHLRSERAEQPFVAVNCAAIPPDLIESELFGVDKGAYTGAVNARAGRFERANGGTIFLDEVIELTPRAQATLLRVLQEGELERVGGDRTRKVDVRLITATNENLEEAVKMGRFRADLFFRLNVFPVHIPPLRERVEDIPLLVEHFLRRHHKEYGKKTLGLSDRAMEACLHYQWPGNIRELENALERGVILTESNESINVESLFPGLATATEGDRLSSEGRLEEESGDSWFRQIIDQGVSLEDLEAGLMRTAMDRCGQNISQAARLLGLTRPAMAYRLKKLDPSLSVKAMGR
What is the function of this protein?
Regulatory protein of the TOL plasmid xyl operons.  In the presence of m-xylene or m-methylbenzyl alcohol XylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon.  XylR interacts with sigma-54.
What are the official names of this protein?
Transcriptional regulatory protein XylR, 67 kDa protein.
Protein: RL331_BACC1
Sequence: MRKKVVLSCEECKNRNYSTMKDTSSVERLEIKKFCKTCNQHTVHKETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PARVA_HUMAN
Sequence: MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
What is the function of this protein?
Plays a role in sarcomere organization and in smooth muscle cell contraction.  Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract.  Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity).  Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis.  Plays a role in the establishment of cell polarity, cell adhesion, cell spreading, and directed cell migration.
What are the official names of this protein?
Alpha-parvin, Actopaxin, CH-ILKBP, Calponin-like integrin-linked kinase-binding protein, Matrix-remodeling-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the parvin family.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Constituent of focal adhesions. Associates with the actin cytoskeleton.
Protein: GPMA_BRADU
Sequence: MSERLLVLVRHGQSEWNLKNLFTGWKDPDLTEQGVAEAREAGRKLKAQGLVFDVAYTSVLTRAQHTLDLILGELGQKGLPTEKNLALNERDYGDLSGLNKDDARKKWGEDQVLIWRRSYDVPPPGGESLKDTLARALPYYVQEILPSVLNGKRTLVAAHGNSLRALIMVLEKLSPEGILKRELATGVPIIYRLNADSTVASKLDLAG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: E4PD_YERPE
Sequence: MAIRIAINGFGRIGRSVLRALYESGRRAEISVVAINELASAEGMAHLLKYDSSHGRFAWDVRQECDSLYVGDDIIRLIHQSEIEQLPWSELGIDVVLDCSGVYGSREDGEAHVASGAKKVLFAHPGGHDLDATVVYGVNHQDLRAEHRIVSNASCTTNCIIPIIQLLDIAYGIESGTVTTIHSSMNDQPVIDAYHQDLRRTRAASQSIIPVDTKLAAGITRIFPKFCDRFEAISVRVPTINVTAIDLSVSVTHPVGVAEVNQLLQKAARGAFRGIVDYTELPLVSMDFNHDPHSAIVDGTQTRVSGQHLIKTLVWCDNEWGFANRMLDTTLAMAKSGF
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.