PharMolix/UniProtQA huggingface dataset:
Protein: DDX55_MOUSE
Sequence: MEHVTEGAWESLQVPLHPRVLGALRELGFPHMTPVQSATIPLFMKNKDVAAEAVTGSGKTLAFVIPILEILLRREEKLKKNQVGAIVITPTRELAIQIDEVLSHFTKHFPQFSQILWIGGRNPGEDVERFKQHGGNIIVATPGRLEDMFRRKAEGLDLASCVKSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEVENLVRAGLRNPVRISVKEKGVAASSTQKTPSRLENHYMICKADEKFNQLVHFLRSRQQEKHLVFFSTCACVEYYGKALEALLKKVKILCIHGKMKYKRNKIFMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEEAYINFLAINQKCPLQEMSLQRNTIDLLPKLRAMALADRAVFEKGMKAFVSFVQAYAKHECSLIFRLKDLDFAGLARGFALLRMPRMPELRGKQFPDFVPVDIDTDTIPFKDKIREKQRQKLLEQKRKERSENEGRKKFIKNKAWSKQKAKKERKKKMNAKRKKDEGSDIDDEDMEELLNDTRLLKKFKKGKITEEEFEKGLLTSAKRTVQLTDLGVSDLEEDS
What is the function of this protein?
Probable ATP-binding RNA helicase.
What are the official names of this protein?
ATP-dependent RNA helicase DDX55, DEAD box protein 55.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
Protein: CLPP_XANOM
Sequence: MSIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEADNPEKDISIYINSPGGVVTAGMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEILAKHTGQSLETIARDTERDNFKSAVDAQAYGLVDQVLERRPEESIQPS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_SERP5
Sequence: MSDETALPLQFTEAAASKVKVLIADEENPDLKLRVYITGGGCSGFQYGFTFDDKVNDGDMTIEKQGVALVVDPMSLQYLVGGSVDYTEGLEGSRFVVTNPNAKTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: DAPH_CLOBJ
Sequence: MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIEKNKDKIKNCRIEQDRRKSAIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVNIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEPPSSDPCTIEDNVLIGANAVILEGIKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: UBIG_METSB
Sequence: MAQREEAGPSSVDPEDVARFDRIGEDWWSADGPMAALHKLNPVRVAYLRDLMSRHFRVEGLPRDRYAPRPLEGLRILDAGCGAGLLAEPLARLGARVTAIDPAPRNIEVARRHAEKSGLSIDYRMTTIEALSGEAATFDAVLAMEVLEHVLDVAGFVRCCGALVRPGGLMFAATLNRTLKSFAFAIVGAEYVLGWAPRGTHDWRRFISPRELARAMAAADLSAFDETGVVFDPLQGGWRLAHDTDINYMMAASKRR
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: GSA_CHLFF
Sequence: MPVIDESTMTYAEACRYFPGGVNSPIRACLPVRIVPPIVSSACRDIFIDSFGNNFIDFCGSWGSLIHGHSHPKILDAICNAASHGTSYGLTSENEISLASTLFSCLDLEDYKLRFVSSGTEATMTAVRLACGVTKCSIIVKFLGCYHGHADVLLKGISVDENNLQNVAHIVDTYFAGQPCLPLTLILPYNDVMIFEEVMHQIGERVACVIFEPICINMGVILPKHGFIESILAMCRRYSALSIMDEVVTGFRMGIRGMRSIMDVTADITVYGKILGGGMPVAALLAHQNIMDHLLPLGTVFQAGTLSGNPVAMAAGKASIELCCEPNFYSKLENLTEGFLSPIEEIIRSKGFPVSLVRSGSMFSFFFRDTPPANLSEVQQCDQERFGLFYRQAFSLGVYLSPASTEASFISSVHSRENLAYTQNVLIDSLVKSFDNV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTC1_CAEEL
Sequence: MGSSPILLVLAISIGLASACFLNSCPYRRYGRTIRCSSCGIENEGVCISEGRCCTNEECFMSTECSYSAVCPELFCKIGHHPGYCMKKGYCCTQGGCQTSAMC
What is the function of this protein?
Ligand for the G-protein coupled receptor ntr-1 (PubMed:23112336, PubMed:23112335).  Plays a role in gustatory associative learning (PubMed:23112336).  Also plays a role in male mating behavior (PubMed:23112335).
What are the official names of this protein?
Nematocin.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7L_SHESR
Sequence: MQVPKNNIYTVSRLNGEVRQILEGQLGKVWLNGEISNFSAPSSGHWYLTLKDHYSQIRCAMFKGRNQSVSFKPVNGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFEALKMKLAAQGLFAADTKRQLPKNIQRIGVITSPTGAAIRDVLHVLARRDPSIEVIIYPTQVQGESADLNICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVDTTISDYVADVRAPTPSAGAELLSQDSDNKSQRLATVLSRLKQSANHYQLKQERRLSLLEHRLQRLDPKRTLQQFEQRFDEMQLRLEAALSNKLHGLSRRQQQLANRLEKQSPKHKLALETNRLNYLATRLQDAMQDTLNQSEQRIKYAAHQLETVSPLATLSRGYSITTDANNQIIDNAAQLSVGDKINTRLRHGQVQSTVTQITDES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_PROM2
Sequence: MNSSNLEKLNCKSSIRDEVVPSRKRVTLPPWLEVAKPRLIPLLLATTLGGMALTEEWPLSSPKLICTLGGGALAAAAAGALNCLWEMELDKRMTRTSKRALPAGKLSSETVFLAAVSCTLAASMLLVSGVNYLAAGLTLLGLFSYVILYTVILKPRTTKNIVFGGVAGAIPPLVGASAATGHVGLSGWWLFGLVMLWTPAHFWALAILLKDDYASVGIPMLPSVKGSVFTAKAISRYGWATVLMSIMGVFALPEGGLLYGIMLLPFNGRLLQLINELKKSPDDLSRAKSLFRWSILYMFGICLLLLISRTQLSVEFEQQSMQIFFSILSLLSN
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KN12A_ARATH
Sequence: MKKHFTLPRNAILRDGGEPHSPNPSISKSKPPRKLRSAKENAPPLDRNTSTPDHRSMRMKNPLPPRPPPSNPLKRKLSAETATESGFSDSGVKVIVRMKPLNKGEEGDMIVEKMSKDSLTVSGQTFTFDSIANPESTQEQMFQLVGAPLVENCLSGFNSSVFAYGQTGSGKTYTMWGPANGLLEEHLCGDQRGLTPRVFERLFARIKEEQVKHAERQLNYQCRCSLLEIYNEQITDLLDPSQKNLMIREDVKSGVYVENLTEEYVKNLTDVSQLLIKGLGNRRTGATSVNTESSRSHCVFTCVVESRCKNVADGLSSFKTSRINLVDLAGSERQKSTGAAGERLKEAGNINRSLSQLGNLINILAEISQTGKPRHIPYRDSRLTFLLQESLGGNAKLAMVCAVSPSQSCRSETFSTLRFAQRAKAIQNKAVVNEVMQDDVNFLRGVIHQLRDELQRMKNDGNNPTNPNVAYSTAWNARRSLNLLRSFGLGHPRSLPHEDNDGDIEMEIDEAAVERLCVQVGLQSSLASEGINHDMNRVKSIHSSDGQSIEKRLPEDSDVAMEDACCHTENHEPETVDNMRTETETGIRENQIKTHSQTLDHESSFQPLSVKDALCSSLNKSEDVSSCPDLVPQDVTSANVLIADGVDDPEHLVNSASPSLCIDPVGATPVLKSPTLSVSPTIRNSRKSLKTSELSTASQKDSEGENLVTEAADPSPATSKKMNNCSSALSTQKSKVFPVRTERLASSLHKGIKLLESYCQSTAQRRSTYRFSFKAPDSEPSTSISKADAGVQTIPGADAISEENTKEFLCCKCKCREQFDAQQMGDMPNLQLVPVDNSEVAEKSKNQVPKAVEKVLAGSIRREMALEEFCTKQASEITQLNRLVQQYKHERECNAIIGQTREDKIIRLESLMDGVLSKEDFLDEEFASLLHEHKLLKDMYQNHPEVLKTKIELERTQEEVENFKNFYGDMGEREVLLEEIQDLKLQLQCYIDPSLKSALKTCTLLKLSYQAPPVNAIPESQDESLEKTLEQERLCWTEAETKWISLSEELRTELEASKALINKQKHELEIEKRCGEELKEAMQMAMEGHARMLEQYADLEEKHMQLLARHRRIQDGIDDVKKAAARAGVRGAESRFINALAAEISALKVEKEKERQYLRDENKSLQTQLRDTAEAIQAAGELLVRLKEAEEGLTVAQKRAMDAEYEAAEAYRQIDKLKKKHENEINTLNQLVPQSHIHNECSTKCDQAVEPSVNASSEQQWRDEFEPLYKKETEFSNLAEPSWFSGYDRCNI
What is the function of this protein?
Plus-end directed kinesin-like motor enzyme that plays a critical role in the organization of phragmoplast microtubules during cytokinesis.  Constitutes a signaling module in association with serine/threonine-protein kinase TIO that is required to support phragmoplast expansion and cell-plate growth in plant cells.  Binds microtubules in an ATP-sensitive manner.
What are the official names of this protein?
Kinesin-like protein KIN-12A, Phragmoplast-associated kinesin-related protein 1, AtPAKRP1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, phragmoplast. Note=Localized to the midline of the nascent phragmoplast (late anaphase) and remains associated with the expanding phragmoplast ring.
Protein: RS11_KINRD
Sequence: MPPKSRTATASRKPRRKEKKNVAHGHAHIKSTFNNTIVSITDPTGAVIAWASAGQVGFKGSRKSTPFAAQMAAEAAARRAQEHGMRKVDVFVKGPGSGRETAIRSLQATGLEVGAIQDVTPSPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: OGT_SULIA
Sequence: MLVYGLYKSPLGYITVAKDDKGFIMLDFCDCVEGNSRDDSSFTEFFHKLDLYFEGKPINLREPINLKTYPFRLSVFKEVMRIPWGKVMTYKQIADSLGTSPRAVGMALSKNPILLIIPCHRVIAENGIGGYSRGVKLKRALLELEGVKIPE
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_RHORT
Sequence: MSRRCAVTGKGVQTGNNVSHSNIKSRRRFLPNLQVNSLMSDLLREPVRMRLSAHGLRTVEHRGGIDAFLLSTPSVELTVELRKVKRRMVKIRDAAAAAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CAS1A_XENLA
Sequence: MTAQLNKVRRAIIDGCNPAMISDLLDDLREKNVLVDSEVEHIKESNNTNRDRCRAMIDSVKKKGDDPSNILLESLVKNHKTLAKSLGLHEPPMAPVPIQEHNADTIKNKDIKGVIPCSAEEFKKIQDTQGDKIYDVRKREGRKGLALIICNEKFENLNERHGAKVDLDGMTKLLNELGYQVHPHTNLTKTEMVKVMKEFAAQEEHADSDSTFIVLMSHGDRQGVCGTDSKKTEKEKGQYEVTNLLEIDEIFSTFNNVNCSKLRNKPKVIIIQACRGENKGGLLVRDDVASPPLEDDGLHFVQREADFICFCSSTPDTVSWRDPTKGSVFITHLIEKMNEYAHCQPLGDIFLEVQSLFKDKCPNSRSQMPTQERCTLTKKFYLFPGY
What is the function of this protein?
Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin-D (GSDMD), into active mature peptides.  Plays a key role in cell immunity as an inflammatory response initiator: once activated through formation of an inflammasome complex, it initiates a pro-inflammatory response through the cleavage of the two inflammatory cytokines IL1B and IL18, releasing the mature cytokines which are involved in a variety of inflammatory processes.  Cleaves a tetrapeptide after an Asp residue at position P1.  Also initiates pyroptosis, a programmed lytic cell death pathway, through cleavage of GSDMD.
What are the official names of this protein?
Caspase-1-A, CASP-1-A, Interleukin-1 beta convertase homolog A, xICE-A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: TES26_TOXCA
Sequence: MSVVHKACLIALLFVSSGVAQQCMDSASDCAANAGSCFTRPVSQVLQNRCQRTCNTCDCRDEANNCAASINLCQNPTFEPLVRDRCQKTCGLCAGCGFISSGIVPLVVTSAPSRRVSVTFANNVQVNCGNTLTTAQVANQPTVTWEAQPNDRYTLIMVDPDFPSAANGQQGQRLHWWVINIPGNNIAGGTTLAAFQPSTPAANTGVHRYVFLVYRQPAAINSPLLNNLVVQDSERPGFGTTAFATQFNLGSPYAGNFYRSQA
What is the function of this protein?
Binds phosphatidylethanolamine.
What are the official names of this protein?
26 kDa secreted antigen, Toxocara excretory-secretory antigen 26, TES-26.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: HBSAG_HBVB8
Sequence: MGGWSSKPRKGMGTNLSVPNPLGFFPDHQLDPAFKANSENPDWDLNPHKDNWPDAHKVGVGAFGPGFTPPHGGLLGWSPQAQGILTSVPAAPPPASTNRQSGRQPTPLSPPLRDTHPQAMQWNSTTFHQTLQDPRVRALYLPAGGSSSGTVSPAQNTVSAISSILSTTGDPVPNMENIASGLLGPLLVLQAGFFSLTKILTIPQSLDSWWTSLSFLGGTPVCLGQNSQSPISSHSPTCCPPICPGYRWMYLRRFIIXLCILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCKTCTTPAQGTSMFPSCCCTKPTDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWYWGPSLYNILSPFMPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: MATK_HUMAN
Sequence: MAGRGSLVSWRAFHGCDSAEELPRVSPRFLRAWHPPPVSARMPTRRWAPGTQCITKCEHTRPKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAGAPASVSGQDADGSTSPRSQEP
What is the function of this protein?
Could play a significant role in the signal transduction of hematopoietic cells.  May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site.  It may play an inhibitory role in the control of T-cell proliferation.
What are the official names of this protein?
Megakaryocyte-associated tyrosine-protein kinase, CSK homologous kinase, CHK, Hematopoietic consensus tyrosine-lacking kinase, Protein kinase HYL, Tyrosine-protein kinase CTK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
Protein: TIG_STRPD
Sequence: MISRIKSFKNALNYDKMNCIEIILRRNDLMSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGFRKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGKEWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEAAQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVTFPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKELEAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEMYFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYNMPADQVRSLLSADMLKHDIVMKKAVEVITSTASVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RECO_RICFE
Sequence: MNIKDVGVIIAKKPLKENTFIITVFTKNHGLYSGVVKESSKKSKFIYQEGNIVDFLWQARLHEHIGMAKCELIKSYTGYFIINKAKLYAFNSVISLIKELFHEREEHSNFFSFLINYLDNLSKNFCFRDYINFELALLAETGYKLDLTKCGVTHVTTDLNYVSPKSARALSYEVGKPYKDKLLILPKFLLSDDSEITLEEKRQASTLTNYFFNRYLFHNNRQAEARQIFMEYILNNS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: MOB2_DROPS
Sequence: MKETLSSKVPTTRTVGVTFDSVSESKSKLKSGSVQGTTATATATGPPSPPSSYVIKCLLKTARFMWQVTTIPAKIGDTLGTLYRYAQDSVDTFLCVAGKARRKERDGDQNSTDTKLYLEESVLERKLPEADLKALVDLPAGLDYNEWLASHTLALFEHVNLVYGTISEFCTQSGCADMTGPGNRTYLWFDEKGKKTRVAAPQYIDYVMTFTQKTVSDESIFPTKYANEFPGSFESIARKILRLQFHVIAHLYAAHFREIALLGLHTHLNLTFAHLTALHRRFNLIDEKETDVLRDLEVALRLTDDTSGQDSSSSVHEHSSSSSSPPVQHQQHQHQQQHNNSSSTSNSTSPAEALHVNSQSNSNSHSNSSNSHTTTASASASLIDGDSAAPPICTQPEAGAGCKPAGSSGLLGGILGDLTSGEFGDTTRYCTSAVPQAAASSSASAAGPGADGAASAALNNGAGALHLNFSNNNNNNHNLNHLNHHHHHHHHQHHHQHHPHGHHGHQGHQGHQGHHQAPASTTVPHSGLIQCNAAGAVGASAGGGGNAVSAATGGATSASSTA
What is the function of this protein?
Required for the normal morphogenesis of a variety of polarized outgrowths including epidermal hairs, bristles, arista laterals, and dendrites.
What are the official names of this protein?
MOB kinase activator-like 2, Mob as tumor suppressor protein 2, Mps one binder kinase activator-like 2.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Trc colocalizes with Mob1 to the cell periphery in wing cells and wing hairs.
Protein: GATA_LISMC
Sequence: MGLFDFSVKELHDKLVKKEISPFDLVSESFNRIESVEDKVGSFITLNKEAAFGVAEELGDAGIDPNNMLSGLPIGIKDNIVTKNLRTTAASKILENFDPIYDATVVSKLKNAQTINIGKLNMDEFAMGSSTETSYFHKTHNPWDLSRVPGGSSGGSASAVAAGEVLFSLGSDTGGSIRQPAAFCGVVGMKPTYGRVSRFGLIAFASSLDQIGPITKNVEDNAYLLEAISGLDANDSTSINQPVERFSNSLTGDIKGLRIGVPKEYLGEGVDPGVKQAVLDALKTLEKLGATWDEVSLPHSEYGVASYYILASSEASSNLSRFDGVRYGYRSPNATTLEELYTKTRSEGFGDEVKRRIMLGTYALSSGYYDAYYKKAQQARTLIKQDFVNVFENYDVIIGPSSPTTAFKIDGMINDPITMYSNDILTVPINLAGVPAISVPCGFSDGLPVGLQIIGNYFEESLLYKVAHAFEQETTFHKEKPNL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: XPO7_MOUSE
Sequence: MADHVQSLAQLENLCKQLYETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQALIQLYARITKLGWFDCQKDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLTNEINQADTTHPLTKHRKIASSFRDSSLFDIFTLSCNLLKQASGKNLNLNDESQHGLLMQLLKLTHNCLNFDFIGTSTDESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSIPPSFSPLVLSCLVQIASVRRSLFNNAERAKFLSHLVDGVKRILENPQSLSDPNNYHEFCRLLARLKSNYQLGELVKVENYPDVIRLIANFTVTSLQHWEFAPNSVHYLLSLWQRLAASVPYVKATEPHMLETYTPEVTKAYITSRLESVHIILRDGLEDPLEDTGLVQQQLDQLSTIGRCEYEKTCALLVQLFDQSAQSYQELLQSASASPMDIAVQEGRLTWLVYIIGAVIGGRVSFASTDEQDAMDGELVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQKSSKLYRRLSEVLGLNDETMVLSVFIGKVITNLKYWGRCEPITSKTLQLLNDLSIGYSSVRKLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTALGRLLMVDLGEDEDQYEQFMLPLTAAFEAVAQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTSFMMLFEWIYPSYMPILQRAIELWYHDPACTTPVLKLMAELVHNRSQRLQFDVSSPNGILLFRETSKMITMYGNRILTLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFGVFRLYGDDALENALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPHVIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRSTKKRTTPLNRESDCFLHIMQQHPAMIQQMLSTVLNIIIFEDCRNQWSMSRPLLGLILLNEKYFSDLRNSIVNSQPPEKQQAMHLCFENLMEGIERNLLTKNRDRFTQNLSAFRREVNDSMKNSTYGVNSNDMMS
What is the function of this protein?
Mediates the nuclear export of proteins (cargos) with broad substrate specificity.  In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form.  Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.  Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor.  XPO7 then return to the nuclear compartment and mediate another round of transport.  The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
What are the official names of this protein?
Exportin-7, Exp7, Ran-binding protein 16.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: PTHP_STAAU
Sequence: MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_BUCAI
Sequence: MPAIIIDGNKIAKKIELKILKKVKQRKKNGERIPGLAMILVGNHIPSQIYVNKKKISCKNVGFFSECWNLPSNINEKEILNIISKLNENKNIDGILIQLPLPPQINHMKILSSIVPDKDVDGFHPYNTGSLCQRTPKLRACTPKGIITMLKYNKIKTHGLHAVMVGASNIVGRPMSLELLLAGCTTTVTHRFTKNLKDHVQNADLLIVAVGKANFLKGSWIKTGSIVIDVGINRLKNGKVVGDVEFKTAYLRASYITPVPGGVGPMTVATLLQNTLEACENHDDI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DPA5A_MOUSE
Sequence: MMVTLVTRKDIPPWVKVPEDLKDPEVFQVQSLVLKYLFGPQGSRMSHIEQVSQAMFELKNLESPEELIEVFIYGSQNNKIRAKWMLQSMAERYHLRQQKGVLKLEESMKTLELGQCIE
What is the function of this protein?
Involved in the maintenance of embryonic stem (ES) cell pluripotency.  Dispensable for self-renewal of pluripotent ES cells and establishment of germ cells.  Associates with specific target mRNAs.
What are the official names of this protein?
Developmental pluripotency-associated protein 5A, mDppa5, ES cell-associated transcript 2 protein, Embryonal stem cell-specific gene 1 protein, ESG-1, Protein pH 34.
What is the protein family that this protein belongs to?
Belongs to the KHDC1 family.
What are the subcellular locations of this protein?
Cytoplasm.