PharMolix/UniProtQA huggingface dataset:
Protein: YIDD_PSEP1
Sequence: MRKLALVPIQFYRYAISPLMANHCRFFPSCSCYAYEAIENHGIWRGGWLAVRRLGRCHPWNDGGFDPVPPAPSSRTSSIAE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NHAA_CUPNH
Sequence: MDRLPPPPPPPRQPLPRAQVLAEKAFSALEHFLHIEAVSGIVLLAAAGIALLWANSPASHSYHALWHTPLSFGIGSHLVSQSLHFWINDALMTIFFLVVGMEIRREIHEGALANVRLSALPMAAALGGVIVPALIYLAINTEMPQRQGWAVPTATDIAFAVGVLALLGKSIPGNVRVFLLALAIIDDIVAVLIIAVAFSGGLDYGGFLVAGTGILMVLGLQWIGVGTAYAYVVPGAILWLGMLKTGAHPTLAGVVLGMMTPVLPGRTRERPLDVAMRALLDLRARATARTPKPEHIAAPLKQLRHAQRELLPPVIRVQMALHPWVAYLVMPLFALANAGVSIDGVDLTSGGSLGAMFGVVLALVVGKPLGIVSVSWLAVRLGWCQLPPDVTWRGVCLVGLLAGIGFTMSIFIATLAFEDVNLLGAAKLGVLLASAIAATIGLTWGFIYARGRRPSMERADESTAAASD
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACSF2_RAT
Sequence: MAVYLGMLRLGRLCVASLGARGPRTPLSRPWPNSKLQGVRAFSSGMVDCTNPLPIGGLSYIQGHTDSHLVNKTVGECLDATAQRFPNREALVIIHENIRLNFAQLKEEVDRAASGLLSIGLRKGDRLGMWGPNSYAWVLIQLATAQAGIILVSVNPAYQASELEYVLRKVGCKGIVFPKQFKTQQYYNILKQVCPELEKAQPGALKSERLPDLTTVISVDAPLPGTLLLDEVVAAGGKEQNLAQLRYHQGFLSCYDPINIQFTSGTTGNPKGATLSHHNIVNNSNLIGQRLKMPAKTAEELRMVLPCPLYHCLGSVGGTMVSVVHGATLLLSSPSFNGKKALEAISREKGTLLYGTPTMFVDILNQPDFSSYDFTTIRGGVIAGSLAPPELIRAIISKMNMKELVVVYGTTENSPVTFMNFPEDTLEQKAGSVGRIMPHTEAQIVNMETGELTKLNMPGELCIRGYCVMQGYWGEPQKTFETVGQDRWYRTGDIASMDEQGFCRIVGRSKDMIIRGGENIYPAELEDFFHKHPQVQEAQVVGVKDDRMGEEICACIRLKSGETTTEEEIKAFCKGKISHFKIPRYIVFVEGYPLTVSGKIQKFKLREQMEQHLKL
What is the function of this protein?
Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA.  Has some preference toward medium-chain substrates.  Plays a role in adipocyte differentiation.
What are the official names of this protein?
Medium-chain acyl-CoA ligase ACSF2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSBA_GRATL
Sequence: MTATLERRESASLWERFCTWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFVAAPPVDIDGIREPVAGSLLYGNNIISGAIIPSSAAIGIHFYPIWEAASLDEWLYNGGPYQLIVLHFLLGVSCYIGREWELSYRLGMRPWISVAFTAPVAAAAAVFLVYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHQLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANNGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGLWPVVGIWFTAMSVSTMAFNLNGFNFNQSVVDSQGRVINTWADILNRANLGMEVMHERNAHNFPLDLASSNSLPVSLVAPSVNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YO07_BPL2
Sequence: MICLFKINGKIASRKKITNAIYCLEQNQENEISELFETGSVDAQNIFNEGNADATIQIVELPNLDKATIKLALFSTLSCIGEDSPDGLPERYHQIFKRLGNELIDMDIDYDKVLSKLVKLAEVIQ
What are the official names of this protein?
Uncharacterized 14.0 kDa protein, ORF7.
Protein: BZIP2_ARATH
Sequence: MASSSSTYRSSSSSDGGNNNPSDSVVTVDERKRKRMLSNRESARRSRMRKQKHVDDLTAQINQLSNDNRQILNSLTVTSQLYMKIQAENSVLTAQMEELSTRLQSLNEIVDLVQSNGAGFGVDQIDGCGFDDRTVGIDGYYDDMNMMSNVNHWGGSVYTNQPIMANDINMY
What is the function of this protein?
Transcription factor that binds to specific DNA sequences in target gene promoters.  BZIP2-BZIP63-KIN10 complex binds to the ETFQO promoter to up-regulate its transcription (PubMed:29348240).
What are the official names of this protein?
bZIP transcription factor 2, AtbZIP2, G-box-binding factor 5, Protein FLORAL TRANSITION AT THE MERISTEM 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: SODM_THEAQ
Sequence: MPYPFKLPELGYPYEALEPHIDARTMEIHHQKHHGAYVTNLNAALEKYPYLQGAEVETLLRHLTALPADIQAAVRNNGGGHLNHSLFWRLLTPGGAKEPVGELKKAIDEQFGGFAALKEKLTQAAMGRFGSGWAWLVKDPFGKLHVISTANQDNPVMGGFAPIVGIDVWEHAYYLKYQNRRADYLQAIWNVLNWDVAEEIYKGA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: CNIH2_HUMAN
Sequence: MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.  Blocks CACNG8-mediated resensitization of AMPA receptors.
What are the official names of this protein?
Protein cornichon homolog 2, CNIH-2, Cornichon family AMPA receptor auxiliary protein 2, Cornichon-like protein.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine. Postsynaptic density. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells).
Protein: PSPD_ECO57
Sequence: MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVARRPLKMLLAVALEPLLSRAANKLAQRYKR
What is the function of this protein?
The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions.
What are the official names of this protein?
Phage shock protein D.
What is the protein family that this protein belongs to?
Belongs to the PspD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MUTS2_STAAT
Sequence: MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEDRTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: GLMM2_SHEAM
Sequence: MSRKYFGTDGVRGKVGEFPITPDFAMKLGWAAGTVMAASGTKEVIIGKDTRLSGYMLESAMEAGFCAAGVNVALTGPLPTPAIAYLTSTFRADAGVVISASHNPYYDNGIKFFSNTGTKLTDEQELEIERLLVSAIEGGAMTCVASDKLGKVRRINDAAGRYIEFCKGTFPNSLSLTGLKIVVDSAHGAAYHIAKNVYRELGAEVISINDKPDGININEHCGATHMDSLQTAVMIHEADLGIALDGDADRLMMVDSKGQVIDGDALLYLLAKSAQQRGEQVSGVIGTLMSNLGFEQALANLGIPFKRAKVGDRYVVELLKETGWRLGGENSGHLLMLDFTTTGDAIVASLQVLRALLESGAGLADAITELNMFPQVLINVRLNGNAAVGLSHPSVSDAVATAESALGNDGRVLLRKSGTEPLIRVMVEAKDAVKANQYAELIADAVRAVFPA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NHAB_SALHS
Sequence: MEISWGRAMWRNFLGQSPDWYKLALLVFLIVNPFIFLANPFIAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVIIGMTSAAHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMVLSLAFCVAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRGEENDMLDDSHIDPHYKTVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLVCGLLTCMLVEKMRWFGYGETLPEKVRDVLQQFDDQSRKKRTRQDKIKLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATALTGVTDEHAIGKAFTESLPFTALLTVFFSIVAVIIDQHLFAPIIQFVLQASEHAQLTLFYLFNGLLSSISDNVFVGTIYINEAKAAMENGAISLKQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLTLIGLLCVEFTLAPATEWMTQAGWLATLS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLGA_RHIL3
Sequence: MKVLSVSSEVFPLIKTGGLADVSGALPIALKAFGVETKTLLPGYPAVMKVIRDAVIRLEFPDLLGERATVLEVQHEGLDLLILDAPAYYDRPGGPYLDPLGKDYPDNWRRFAALSLAASEIAAGLMPGWRPDLVHTHDWQAALTSVYMRYYPTPELPSVLTIHNIAFQGQFGSEIFAGLRLPAHAFTTESIEYYGTVGFLKGGLKTAHAITTVSPTYADEILTSEFGMGLEGVIASRVDDLHGIVNGIDTDIWNPATDPVVHTHYGQTTLKNREENRRSIAEFFGLDNDDAPIFCVISRLTWQKGMDIVANVADEIVAMGGKLVVLGSGEAALEGALLASASRHPGRVGVSIGYNEPMSHLMQAGCDAIIIPSRFEPCGLTQLYGLRYGCVPIVARTGGLNDTVIDANHAALAAKVATGIQFAPVTETGMLQAIRRAMHFYQDRKLWTQLQKQGMKSDVSWEKSAERYAALYSSLVSKGM
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: ACVR1_HUMAN
Sequence: MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC
What is the function of this protein?
Bone morphogenetic protein (BMP) type I receptor that is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation (PubMed:20628059, PubMed:22977237).  As a type I receptor, forms heterotetrameric receptor complexes with the type II receptors AMHR2, ACVR2A or ACVR2B (PubMed:17911401).  Upon binding of ligands such as BMP7 or GDF2/BMP9 to the heteromeric complexes, type II receptors transphosphorylate ACVR1 intracellular domain (PubMed:25354296).  In turn, ACVR1 kinase domain is activated and subsequently phosphorylates SMAD1/5/8 proteins that transduce the signal (PubMed:9748228).  In addition to its role in mediating BMP pathway-specific signaling, suppresses TGFbeta/activin pathway signaling by interfering with the binding of activin to its type II receptor (PubMed:17911401).  Besides canonical SMAD signaling, can activate non-canonical pathways such as p38 mitogen-activated protein kinases/MAPKs (By similarity).
What are the official names of this protein?
Activin receptor type-1, Activin receptor type I, ACTR-I, Activin receptor-like kinase 2, ALK-2, Serine/threonine-protein kinase receptor R1, SKR1, TGF-B superfamily receptor type I, TSR-I.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DNAI2_MOUSE
Sequence: MEIVYVYLKKRSEFGKQCNFSDRQAELNIDILPNPELAALYVERNPVDTGIQCSASMSEHEANTERFEMESCGVNHVEGGWPKDVNPQELEQTIRFRKKVEKDENYINAVMQLGSIMEHCIKQNNAIDIYEEYFDDEEAVEVTEEAPSAKTINVFRDPQEIKRTATHLSWHPDGNRKLAVAYSCLKFQRAPMSMNYDSYIWDLENPNRPEIALKPLSPLVTLEYNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIEFSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKISEPIEVVIMDISRKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTQAEKIVCTFYGHHGPIYALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLSDGAWSPVRPAVFFTTKMDGTLDIWDLVFKQCDPALSLKVCDDPLFCLRVQDNGCLIACGSELGTTTLLEVSSSLSTLQRNEKNIASSIFERETRREKILEARHREMRLKEKGKVEGKEDDQKEEEAALDLDELVGKAEEEFFEVIFSELKRKEAEALKKKPKPRKKSSVKVEAEEEVEENVGEEEEAGGIIGIDAVEDMSEEAGEEQEDVPT
What is the function of this protein?
Part of the dynein complex of respiratory cilia.
What are the official names of this protein?
Dynein axonemal intermediate chain 2, Axonemal dynein intermediate chain 2.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Dynein axonemal particle. Note=Located in the proximal region of respiratory cilia.
Protein: ESRP2_CHICK
Sequence: MTASHSDSLVVLFGATAGAYGAKLGSDERELILLVWQVVDLPSKKVGTLHKSLVKADNLELSDQCREVSGLTAEGLGKAEPLDRVLQQFIQLVSSDLKVFGRNSYTLCSDGQLLIRQVLHPETSKKNFLLSDCFYSFYDLRKEFHTCYPSSAAVKDQTIKTMAEYLGLGTDEAEEDFGVWQVKTMVAIIFSMLSENCDHIFTDPETVKYKYETGPCSKSETVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFVNSEQRDLALERHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFLSKENQVIIRMRGLPFTATQEDVLGFLGPECPVTGGKEGLLFVKYPDGRPTGDAFVLFSCEEYAQNALKKHKEILGKRYIELFRSTAAEVQQVLNRYMSTPLIPTLPTPIIPVIPPPYTIATGSIRDCVRLRGLPYTAGIDDILDFMGDATADIKPHGVHMVLNQQGRPSGDAFIQMKSADKAFMVAQKCHKKMMKDRYVEVFQCSGEEMNFVLMGGTLNRSGLSPPPCLSPPAYAAFQTAAVIPAEAALYQPQALLPTARTPQASAAAPPAVTYYPAQAAQLYMNYTAYYPSPPVSPTTVGYLAAPPGAVAAAATATHTPLLPQPGALVRMQGLPYNTGMKEILSFFQGYQYAPDDYNGLIQLSEQARSVLQAPKEWVCL
What is the function of this protein?
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms.  Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2.  Acts by directly binding specific sequences in mRNAs.  Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity).
What are the official names of this protein?
Epithelial splicing regulatory protein 2, RNA-binding motif protein 35B, RNA-binding protein 35B.
What is the protein family that this protein belongs to?
Belongs to the ESRP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPB_STRAW
Sequence: MSKLRVAVLGVKGRIGSEAVRAVEAAEDMELVAALGRGDKLETLADTGAQVAVELTTPASVMGNLDFCVRHGIHAVVGTTGWTDDRLAQLKGWLAQSPETGVLIAPNFSIGAVLTMKFAQLAAPYFESVEVVELHHPNKVDAPSGTATRTAQLIAEARRKAGSAPQPDATVTALDGARGANVDGVPVHAVRLRGLLAHQEVLLGAEGETLTVRHDSLHHSSFMPGILLGARRVVTTPGLTFGLEHFLDLN
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_ARTS2
Sequence: MTSVSLGMPSAPPPVLAPRRKTRQIKVGSVGVGSDSPISVQSMTTTPTTDINATLQQIAELTASGCDIVRVACPSADDAEALPIIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNIRKFDDQVKEIARAAKDHGTSIRIGVNAGSLEPGILKKYGKATPEALVESAVWEASLFEEHGFHDFKISVKHNDPVIMVAAYEMLAEKGDWPLHLGVTEAGPAFQGTIKSATAFGALLSRGIGDTIRVSLSAPPVEEIKVGNQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEQVTAGLEGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESEIVETLIEEAMRIAEEMGEADGEDAVKGSPVVSVS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TRMD_SERMA
Sequence: MFIGIVSLFPEMFRAITDYGVTGRAVKNGLLSVQCWSPRDFTYDRHRTVDDRPYGGGPGMLMMVQPLREAIHAAKAAAGEGAKVIYLSPQGRKLDHTGVCELAANQKMILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVLGHQASAEEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLESLALTDEQAVLLAEFQREHQARQQDYEGNV
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_BUCAP
Sequence: MKKKNNIILTIQKNCKNTKNIPKKYIFEKWIKKVLYKKKNVNLINIRIVDEREMKNINLKYRGKNKSTNILSFKFDLFINKNQTLLGDLVLCKKIIEKESLKYQKTLESRWAHMIIHGTLHLLGYDHKNKKEKKIMEKIENKIMLFLNYEKPYFMKSS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDIF2_MOUSE
Sequence: MVVTRSGLSRTRLQESSQQKRSAPRRIGTHLESTKESGSDGSTAESQPAEKQHSRSSSRTTGPAEIIVLISDDEASETESHTSGVTSVLEDQEPIVRVTRKRQIVIASTSKSTVRKRQKVAPQHASADEVVVSEAESHVSGVSMVVPSTERSSRNKANSQRDSSQESQSGTVSDAELSCSGISSLEILPRTTARNVKKKLQFPAEKNDTKITPGNKKQIVGMSVCSEDSDATQLSARPLSQRNMPNVSDSETYNSDFDDSSPRNSGKKLTAQNHQNLHIQEEKRANVVSLTEVRKENCKSLDEEDLKITEEKVINEKDSQRSLSEAQDTSLQQSVSQNHSSTPNKKPTFQLSSPDRKALMKSLEHKFAVVNVERWNDKRGGSGKKSDLAQLGGGGGGGDDNEPTGAGISDDKSSQSGVPLECDTKPCKSELSMTQDTTDSPVLLFLSSDESQQSDSSENERDTLCSVENNGQKEASAEDLEDAACDSALFVIDKTPGLSADKNFYLEDKAPSEVAIEEEKEEEEKEEENSEEDSSDSDENKDESSDEEDLLSNTKSKLLKLTSSSIDPGLNIKQLGGLYINFNVDKLQPHKETLTQIKEKKKNELLQKAVITPDFEKKHCVPPYSESKHRLQKQRRKERQKTAGNGWFGMKAPELTDELKNDLRALKMRAGMDPKRFYKKNDRDGFPKYFQVGTIVDNPADFYHSRIPKKQRKKTIVEELLADSEFRRFNRRKYSEIMAEKAANAEGKKFKKKKKFRN
What is the function of this protein?
Regulates the transcriptional activity of DNTT and ESR1.  May function as a chromatin remodeling protein.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Deoxynucleotidyltransferase terminal-interacting protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y054_METJA
Sequence: MDRHVMEALGKARVVVENGRVVEVTEPKIKYCPLFAKHRGIKEITKESIKENIEFRIKDFGLFTKNRVVEESRYIVPFGASEILMSALKRKAIDVAVIVADCAGTIITSNPNLVQGLCGRISGIIETSPILEVIEKIEKAGGVVLNKKTAEINQFEGVKKAIELDYKKIAVTVTNLEDAKRCKSLENDEIKILTFGVHLTGIEGSEEIAKYFDLVTACASKVLREKLKGKIKAQIGKTIPIFALSDFGKEILLERAKDLDKVLISIENLPVLNDNQPKPLI
What are the official names of this protein?
Uncharacterized protein MJ0054.
Protein: PRL_CHEMY
Sequence: LPICPSGSVGCQVSLENLFDRAVKLSHYIHSLSSEMFNEFDERYAQGRGFLTKAINGCHTSSLTTPEDKEQAQQIHHEDLLNLVLGVLRSWNDPLLHLVSEVQSIKEAPDTILKAVEIEEQDKRLLEGMEKIVGQVHPGEIENELYSPWSGLPSLQQVDEDSRLFAFYNLLHCLRRDSHKIDNYLKLLKCRLIHDNDC
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: INT8_DICDI
Sequence: MNKIFGVKIDSQQKKRQQSNKNLTVFNNGRYLIYIGDIHFDRKFHREALRYYLLGCGLETAFYSDPVKTSVTNSKYLTFLSRRIFDCFYFLRAPMQAIVVSQFFGNLNQTCLVSFKIIQEEYYQLDTNYFQYIWELPLLEILLTTFTKQKDLKKIYLINQIISNPIINENNHPDIRKNFIKNTKHNFWKAISSNYLLQ
What is the function of this protein?
May be a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 8-like protein.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROA_SALCH
Sequence: MLEQMGIAAKAASYKLALLSSGEKNRVLEKIADELEAQMESILSANVQDVEQARANGLSEAMLDRLALTPARLKAIADDVRQVCNLADPVGQVIDGGLLDSGLRLERRRVPLGVVGVIYEARPNVTVDVASLCLKTGNAVILRGGKETHRTNAATVRVIQKALKACGLPEAAVQAIDNPDRSLVNEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIFVDSSADIAPALKIIVNAKTQRPSTCNTVETLLVHQDIAERFLPALSKQMAESGVTLHGDETVMQALHGPAKLVPLKPEELDNEFLSLDLNVVVVENMDGAIAHIREHGTQHSDAILTSDMHNAARFVNEVDSAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGFGDGTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK20_GOSBA
Sequence: MTRIKRGYIARRRRKKISLFASSFRGAHSRLTRTITQQRIRALVSAHRDRDRKKRDFRRLWITRINAVIRGVGVSYSYSRLIHNLYKKQLLLNRKILAQIAISNRNCLYMISNEIRKEGDRKESNEML
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SLYX_XANC5
Sequence: MHEQLPLHDRALEARLIELETRLSFQEQALNELSEALADARLTGARNAELIRHLLEDLGKVRSTLFADAADEPPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: C170L_HUMAN
Sequence: MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTLVDRVFDESLNFQKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRVNPDGEEEDVTVHK
What are the official names of this protein?
Cep170-like protein, CEP170 pseudogene 1.
What is the protein family that this protein belongs to?
Belongs to the CEP170 family.