PharMolix/UniProtQA huggingface dataset:
Protein: ODO1_BRUA2
Sequence: MAKQEQAPDRANDVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTRKNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSVRAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNVLGLEYATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVLSQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLEIVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGLKGHRVAGTLHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAKVATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEGLVTQDDIDRMKADWRQKLEGEFEAGQSYKPNKADWLDGAWAGLRTADNADEQRRGKTAVPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGEGIDWATAESLAFGSLAVEGHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGYEYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGPEHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRAISTLAELSGESSFHRLLWDDARYNKDKGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGIDDVYLLRVEQLYPFPAKALINELSRFRHAEMVWCQEEPKNMGAWSFIDPYLEWVLAHIDAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDALG
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: CBSX2_ARATH
Sequence: MGSISLSNSMPITRLPLLTSLYHQSFLPISSSSFSLLPLSNRRRSSTFSPSITVSAFFAAPASVNNNNSVPAKNGGYTVGDFMTPRQNLHVVKPSTSVDDALELLVEKKVTGLPVIDDNWTLVGVVSDYDLLALDSISGRSQNDTNLFPDVDSTWKTFNELQKLISKTYGKVVGDLMTPSPLVVRDSTNLEDAARLLLETKFRRLPVVDADGKLIGILTRGNVVRAALQIKRETENST
What are the official names of this protein?
CBS domain-containing protein CBSX2, chloroplastic, CBS domain-containing protein 1, AtCDCP1, Protein LOSS OF THE TIMING OF ET AND JA BIOSYNTHESIS 1, AtLEJ1.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CLPP_LACDB
Sequence: MLVPTVIEQTARGERAYDIYSRLLKDRIIMLSGDVNDQMANSIIAQLLFLDAQDNTKDIYMYINSPGGVITSGMAIVDTMNFIKSPVSTIATGMAASMASIILAEGEKGKRFALPHATVLIHQPLGGAQGQATEIQIAAEEILKTRKMINEILAKDSGQDIETIKRDTERDHYMTAQEAKDYGLIDDIMVNQNK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIL4_RHIO9
Sequence: MSVLIETSLGDIVIDLYTEECPKTTLNFLKLCKIKYYNFAPFFNVQKDFMAQTGDPTGKGDQGQSVYGILGGSRYFPAEIHPTLKHVRRGMVSMAVAADASIETGGVSGSQFFITLGENLDYLDGKYTLFGEIAEGFDVLDKINEAYCDEQGRPFRDIRIKHTVVLDDPFPDPDGLVIPDESPLPTKEQLESMRIGEDEDLEEMGDPEELEKRVRAREAKAHALTLEMIGDLPFAEVKPPENVLFVCKLNPVTRDEDLEMIFSRFGLIHSCEIIRDRQTGDSLSYAFVEFENKEDAEEAYFKMQSVLIDDRRIHVDFSQSVSKLHKDWIAKRTGAGKESMGGFDNLTKRTRYREEGENNDKRDYDLVFDKGDYKRKRDEDSSRDRRRRDGSRDRYSSRRDDERSSRRRDDERSSRRRDDSREKYRRRNDSRDRHSSRRDDDSKRNR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 4, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBEY_CUPMC
Sequence: MVALLAEHTDTRQQAGLLVRPDNSDALSVAVTATPIVTTTGTPATPPALELDVQHGDGVSKRNGLPSRKQIEKWVKSALYADAALTVRFVDETEGRTLNRSYRGKDYATNVLTFAYAENDDDPVAGDIVLCCPVVESEAKAQKKSLEAHYAHLIVHGVLHAQGYEHDDDTEAEEMEAIETETLQALGFEDPYKPIRE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_SOLUE
Sequence: MRRIRIYLAYDGGPFHGWQVQPGLATIQGILEEIVGGMEGKPVHVAGSGRTDAGVHALAQVAAFSIENPIPVENLRRAVNRLLPPAIRILCAEEVQADFHPRFDAVAKTYEYRMFRDEVCSPFEWPYVYHHPYPLDEARMATLARAFEGEHDFTPFAASDARDAEGKSKVRTIFSSTLDRTPQRLVYRVRGSGFLKHMVRNIVGTLIEAGRGNIADLNSLPARSGATAPAKGLFQVSVEY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: IQCB1_HUMAN
Sequence: MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQYCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGRQLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQIGSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKLFSTPSPVIRSTATKLLLLMAESHQEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP
What is the function of this protein?
Involved in ciliogenesis.  The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (PubMed:21565611, PubMed:23446637).  Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos.  May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (PubMed:25552655).
What are the official names of this protein?
IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localization to the centrosome depends on the interaction with CEP290/NPHP6.
Protein: RL10_KINRD
Sequence: MPKPRNIAAVKQLTALFQESNAAVLTEYRGLSVAQLTQLRTALGPDTTYAVLKNTLTTIAAKEAGVTAFEGQLSGPSAIAFITGDPVEAAKGLRDFAKTNPQLIVKSGMLEGRAISAADVTALADLESREVLLSKVAGVLKATQSKAAALFQAPLSKTVRTVEALREKQAAGAPAEAAPVEAPAAETVDA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PUR7_CALMQ
Sequence: MSLGEGKLIYEGKAKRVYLINNEELVMEFKDEVTALDGARKEYAPGKGKLAASQTAFFMSYLNESGVRTHFINWDGDRRIHVRRLRMIPVEVIVRNYAYGSFIRRMPLIKPLTKFTTPLVEFHLKNDELHDPLILIEDIIEAGLTSMEQVMEIRSVSLKVNHLLSELLGKYGLTLVDFKLEFGVNSNGALVLADELSGDTMRVLMNGKHLDKELFRMGGSVKELIEAYSRLNSILGLGLKG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MURC_GRABC
Sequence: MRALPLTIGTIHFVGIGGIGMSGIAEVLHNLGYAVQGSDISDNQNVRRLREAGIQVMIGHDAANLGTAQVVVISSAVGRDNPEVAAARAKLIPVVRRAEMLAELMRLKWAVAVGGTHGKTTTTSLIAAVLEAAQLDPTVINGGIINAYGTNTRLGAGEWMVVEADESDGSFLRLPAVIAVVTNMDPEHLDHWGTAEAMEAGYQQFVSNIPFYGFAVLCIDHPTVQKMIPQLSDHRIITYGFSPQADVRAERINTDKFGATFEVVITDRQTRRTRRTPPLRLPMLGEHNIANTLAAIAVAVEMGISDSVLQSAFASFKGVKRRFTKTGETGGITIIDDYGHHPVEIAAVLRAARQAGARDVIAVVQPHRYSRLASLFNEFCTCMNDAGTVIVADVYNAGESPIEGVDRDSLVDGLRTSGHKSVVPLPGPEHLAEMIHAIARPGDFVVCLGAGNITAWAQTLPEELATLQAKSSKIRRTGSGG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_BURPS
Sequence: MAQTLLNDTFLRALLREPTDYTPIWLMRQAGRYLPEYNATRARAGSFLGLAKQPDYATEVTLQPLERFPLDAAILFSDILTIPDAMGLGLDFAAGEGPKFAHPVRTEADVAKLAVPDIGATLGYVTDAVREIRRALTDGEGRQRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKSMAYARPDLMHRILDVNAQAVAAYLNAQIEAGAQAVMIFDTWGGALADGAYQRFSLDYVRRVLAQLKREHDGARVPAIAFTKGGGLWLEELAATGVDAVGLDWTVNLGRARERVAGRVALQGNLDPTILFAPPEAIRAEARAVLDSYGNHPGHVFNLGHGISQFTPPEHVAELVDEVHRHSRAIRSGAGS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_EUOMA
Sequence: MSPQTETKAMVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CU074_HUMAN
Sequence: MAYVFNLSCLGSQVERLLEARSSRPTWIIQPSPKKAPEACFSFHSSYERNWA
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00308.
Protein: FADI_SHELP
Sequence: MSELQQVRNAKGDRIAIVMGLRTPFAKQATAFHGVSALDMGKMVVNELLSRSELDPKEIEQLVYGQVVQMPAAPNIAREIVLGTGMNVSTDAYSVTRACATSFQSTVNVAESIMTGNIEIGIAGGADSSSVLPIGVSKKLAHALVDLNKARSFGQKWAIIRRLGLKDLLPVPPAVAEYSTGLSMGQTAEQMAKTYNISRADQDALAHRSHTLATETWDSGHLRDEVMVAHVPPYKSFIDRDNNIRENSSLDSYAKLRPAFDRKHGSVTAANSTPLTDGASAVLLMSESRAKALGYEPIGYIKSYAFSAIDVWQDMLMGPSYATPLALKRAGMELEDLTLIEMHEAFAAQTLANMQMFASKKFAKEKLGRDRAIGEIDMTKFNVLGGSLAYGHPFAATGTRLITQVCRELKRRGGGTGLATACAAGGLGAAMIVEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLC5_SALTM
Sequence: MMTQSIRRSMLTVMATLPLLFSSATLHAQANSVQQQLEALEKSSGGRLGVALINTADNSQILYLADERFAMCSTSKVMAAAAVLKQSESDKHLLNQRVEIKASDLVNYNPIAEKHVNGTMTLAELGAGALQYSDNTAMNKLIAHLGGPDKVTAFARSLGDETFRLDRTEPTLNSAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRAQLVTWLKGNTTGSASIRAGLPKCWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQPEQKAESRRDVLAAAAKIVTHGF
What is the function of this protein?
Has cefotaxime-hydrolyzing activity.
What are the official names of this protein?
Beta-lactamase CTX-M-5, Cefotaximase 5.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: CAP18_RABIT
Sequence: METHKHGPSLAWWSLLLLLLGLLMPPAIAQDLTYREAVLRAVDAFNQQSSEANLYRLLSMDPQQLEDAKPYTPQPVSFTVKETECPRTTWKLPEQCDFKEDGLVKRCVGTVTRYQAWDSFDIRCNRAQESPEPTGLRKRLRKFRNKIKEKLKKIGQKIQGFVPKLAPRTDY
What is the function of this protein?
CAP18 binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria.  Has antibiotic activity.
What are the official names of this protein?
Antimicrobial protein CAP18, 18 kDa cationic protein, 18 kDa lipopolysaccharide-binding protein, CAP18-A.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURB_PARMW
Sequence: MLSTRLALRSNIPMADFTTWRVGGPAQWLLEPASVDETLEALQWAQQEHLPCRVIGAGSNLLIHDDGLPGLTLSLRKLQGASLNAENGVVEALAGEPIPTLARRAARAGLNGLAWSVGIPGTVGGAAVMNAGAQGGCTADWLESVRVAPLVGGVSFELSRDELDFDYRHSRLQDEELVVLSARFRLEPGHDPEEITRITSGNLSHRTSTQPYTQPSCGSVFRNPEPLKAGRLIEGLGLKGNRVGGAEVSTLHANFIVNTGAATAADIDSLIQRVQQQVEAAHSLHLHPEVKRLGFTEAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_HALHL
Sequence: MSQVPEDLKYTRNHEWVRVEADGSVTVGITEHAQESLGDLVFVEPPEAGTQVQAEEACAVVESVKAASDVYAPISGEVTQGNEALADNPEAVNTDPYGDGWIMRIQPADTSEIDGLLDAAAYQELVADEG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: PP4R2_PONAB
Sequence: MDVERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDFRTSAPEPRGPPNPNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTGTDKFLRGVEKNVMVVSCVYPSSEKNNSSSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKSHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSAVVGETETSSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSNDSSDCHETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).  May regulate the activity of PPP4C at centrosomal microtubule organizing centers.  Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs.  The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA double strand break repair (By similarity).  Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner.  RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 2.
What is the protein family that this protein belongs to?
Belongs to the PPP4R2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2.
Protein: BN3D2_XENLA
Sequence: MSNSESVPHVDPGAAPYGNFPNYYSFNPPENRISLLPAELLHKLFRKPAESDSSTQPLLGLDVGCNTGDLSVALYNHLTEPHSKSSDVPVHFLCCDIDPDLITRARASNPFPDFISYATLDIMDSSAVRGPVNDFLQQFARSTFDIAFCMSVTMWIHLNYGDQGLVTFLGHLANLCDYLLVEPQPWKCYRSAARRLRKLGRQDFDHFHSLSIRGDMAENITQILTAEGAAKLIHIFGNTSWDRSLLLFKIQRHPC
What is the function of this protein?
O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1.  Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing.  The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1.  Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
What are the official names of this protein?
Pre-miRNA 5'-monophosphate methyltransferase, BCDIN3 domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_UREP2
Sequence: MLKLSTNEIRKKWIEFFESKDHLFIEPKSLIPKNDPTLLWINSGVSTLKDYFSGKVKPPHKRLVNSQKAIRTNDIFNVGLTSRHHTFFEMLGNFSIGDYFKKEAIDWAYEFLINVLKIDVKKLWVTVFEDDQFTNDEWIKLGIIKEQIIKCNRDRNFWDVGNGPCGPCTEIHYDRGERFDPNKIGSKLILEDIENDRYVEIWNIVFSQFNNDGHNNYTELLQKNIDTGAGLERIACISQDVPTNFDSDVFMRITKSVEQFSEYKYDMNEYFHPNVTQNKINFAYKVIADHMRATVFAIADGAIPSNKERGYILRRLIRRTMVLVRRLNINNLLWVDAVVDAIASTMGDFYTYLKDEKTLTKIKMILNKEVQLFEKTLQLGLNIFENSIRNQELDKEITFKLVDTYGFPIELIKEICEQRNVKVDLEAFDAMFKHHQLISKANKANLKVMESQNESLMQLDVDSTFHYEIFRWENAKIITLFNEDFELVDGLDHEDGYVVFDNTCFYATSGGQQHDTGYIIKNDQQFFVDDVFKAPNRQHVHHVKNASLSMNEHVILQINEQDRKSITANHTAEHLLHYCLKHVLSPDIKQEGAAKYPHKVTFDFTYHAQPTKAQLDKLENVLNEMVQSNFDVQELHMDLDEAKAVGAAAYFEDVYKKLKGKLRVIKMGPSIELCGGTHAHHTSEIERIKIVECASKGAGSWRITMVTGHDNLAKYIHDLYVDYLNEINHLKVNLDINDHKLNDLYNAFANWKNLSIDDYDLLNEKFAELKQSLINFKIEFDKQNAKQAIIDIKNTFNTQLTNKRVHVFKNTDNKNIFNALNELINENQDTLFISFNLDDNKIQYLLAINEKFATTNQINLNKYIKELNTISNGKGGGKPYFVQGGTSEQEKLDELLTVVDKWVINA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABI1_HUMAN
Sequence: MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD
What is the function of this protein?
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2.  May play a role in regulation of EGF-induced Erk pathway activation.  Involved in cytoskeletal reorganization and EGFR signaling.  Together with EPS8 participates in transduction of signals from Ras to Rac.  In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex.  Regulates ABL1/c-Abl-mediated phosphorylation of ENAH.  Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level.  In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.
What are the official names of this protein?
Abl interactor 1, Abelson interactor 1, Abi-1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Eps8-binding protein, Nap1-binding protein, Nap1BP, Spectrin SH3 domain-binding protein 1, e3B1.
What is the protein family that this protein belongs to?
Belongs to the ABI family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, growth cone. Postsynaptic density. Cytoplasm, cytoskeleton. Note=Localized to protruding lamellipodia and filopodia tips. Also localized to neuronal growth cones and synaptosomes. May shuttle from the postsynaptic densities to the nucleus (By similarity).
Protein: PYRF_SPHAL
Sequence: MTSPIYLAIDTPHLDAALTLAQKVRHHVGGLKLGLEFFCANGHHGVHEMAKLGLPIFLDLKLHDIPNTVAKAIQALRPLEPAILTVHAAGGRAMLEEAKAVAGKDTRVIAVTVLTSLDAPDLEDIGLTGTPHDQVVRLAALAREAGLDGIVCSGQEVKSARKAWPGGFFVVPGVRPANGRIGDQKRIVTPAQAMSDGASILVVGRPITQSSDPDLAAREIEATL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL19_RHOJR
Sequence: MNTLDFLDKKSLRDDIPEFRPGDTLNVHVKVIEGSKERVQVFKGVVIRRQGGGVRETFTVRKVSFGVGVERTFPVHSPNLAQIEVVTRGDVRRAKLYYLRDLRGKAAKIKEKR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: HSPQ_BAUCH
Sequence: MIASKFGIGQQVRHKLFGYLGVIIDVDPEYSLDKPYIDKIAADDSLRTAPWYHVVMEDEDGKPVHTYLAEAQLGYEAFLEHPEQPTLDELAESIRLQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_CENSY
Sequence: MRSPPICMKRTPKLARIRETARCKGADLCPASGRVFIGASGKRPRLSAQEYKHIVRILGNDLPGEKKAVVGLRQIRGIGYGFATAILDVLKIDNNSNIGYLTDEQVASIEKLLQDPAGAGFPTWFLNRRKDLETGEDRHIFTSDIEFTVRNDVERERVSGSWKGYRHMFGLKVRGQRTRNTGRKGGAVGVAKGGKVMPAKGGAGAPPQEEAAGAEPAKTDAPEEKKA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: URE2_BURA4
Sequence: MIPGEILTDDGEHELNAGRPTLTVVVANTGDRPVQVGSHYHFFEANDALSFDRAAARGFRLNIAAGTAVRFEPGQTRTVELVELAGERAVYGFQGKVMGPL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_BORBU
Sequence: MSAKINAKKLEMFDLLKQFIDSKQNLFFLDYRGLNVAQLTELRNKIEGEHGSLKVVKNNIMKMVLKEKNINVVDSCLVGPTVVVTALEEANVIAKIFYDFVKSSTLKVKGGFVLGEFYDEAKVQAYSKLPTKKESISLFASVLKAPVSKLARTLKALADVKN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: COX16_CRYNB
Sequence: MPPFATRPLNSTKSHPIFAQIRRHPFILFGIPFIGIIVGSSFALQAFTQTRYDYQETKVKSVGKEEELGMKSGRRKIDLKEEYYFSMASVSQDDYEPVRVPRPVGVPEWGGGRSGEEAPMKGYRKEDRWV
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  May participate in merging the COX1 and COX2 assembly lines.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.