PharMolix/UniProtQA huggingface dataset:
Protein: MOBA_BRUME
Sequence: MRAGQPKITGAKITGAIIAGGQSSRMQAGGVSGDKFLQPLGSAPVIAHVIARLQPQVDTLFINSKGDLSRFAAFGLPAVKDIAMNHGGPLVGLLTCLAHASPCRLLLTSAADTPFLPCDLASNLIRKQAETGARIILACSNERVHPIVGLWHTDLVPDLEKWLQYAEKASIFWFAKHIGFEVVNIPLAHAPRLAESYDPFFNINLPDDLLKAREINEALQA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_PSE14
Sequence: MAQVKRIRRNVSGIILLDKPLGFTSNAALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLDSDKSYETLAQLGKTTTTADSEGEVLLTRPVTVGRDDIEAVLPHFRGQISQIPPMYSALKRDGQPLYKLARAGEVVEREPRSVTIARLELLACEGDTARLSVDCSKGTYIRTLVEDIGEKLGCGAYVAELRRTQAGPFTLAQTVTLEELEQVHADGGNEAVDRFLMPSDSGLLDWPLLKFSEHSSFYWLHGQPVRAPDAPKFGMVRVQDHEGRFIGIGEVGEDGRIAPRRLIRSE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: WAPD_DEMVE
Sequence: MSSGGLLLLLGLLTLWAELTPVSGQDRPVKPGLCPPRPQKPPCVKECKNDWSCRGEQKCCRYGCIYECRDPIFVK
What is the function of this protein?
Damages membranes of susceptible bacteria.  Has no hemolytic activity.  Not toxic to mice.  Does not inhibit the proteinases elastase and cathepsin G.
What are the official names of this protein?
Veswaprin-d.
What is the protein family that this protein belongs to?
Belongs to the snake waprin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GVP17_DACSA
Sequence: VSLREQWNEQARERQREISARKTETVALLQEANQERVLVAQQQKALAIELKNQLAQFHEQLETLVGN
What is the function of this protein?
May confer stability to the gas vesicle membranes.  Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.
What are the official names of this protein?
17 kDa gas vesicle protein C.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type C family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: RECF_CHLAD
Sequence: MYIHHLALRDFRNYRRQDVALSPTTILLYGPNAAGKTSLLEAIFYLATTRSPRLSSDRDLVRWDAVGEAGAPPFARIAADVERRIGPVRLEILVQRRLDDGGQPLNGAQKLVRIDKRPARAIDLIGQLRVVLFTPTDVMLVDGPPAERRRYLDITLSQLDPHYVRTLAYYQKILLQRNSLLRAWREQRRLPRNVDAELGYWDQELAAAGGYLLAERLRAVVELSALAGSIYRKISGGEHELQIEYIASCDLDAARDAGSLAERLRLAFAAQRTDELARGQTLCGPHRDDLVFNVAGVNLGRYGSRGQQRTIALALKIGEAELMQQRGGDAPVLLLDDVLSELDNRRRMHLLDLILRPQQQTLLTATNLSDFSADFLAAARRFRVEDGQLFAG
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_METBU
Sequence: MADQSSHQKYEFKKKLESLRGKKGRGTELISLYIPPDKQISDVVSQLRNEHSQASNIKSKLTKTNVQGAIDSIMSRLRYGTVPENGIVYFTGAVDVGANKTNMETTIVEPPQPIITYRYHCDSSFFLTPLEDMLKEAKTYGLLVLDRREATVGLLTGKQIEAFRNLTSTVPGKQRKGGQSAHRFQQLRLIAIHDFYKRIGDAASEVFLAVEQKDFEGVLIGGPSPTKEEFEAGNFFHHEIEKKVLDLFDVAYTDESGLSELVNAASERLEDLDLMVEKKLMQQFFRELVSDSGKATYGEDNVRENLIIGAVDILLISEDLRAVRETVKCTSCDYEQKTSREFKPGDSSSPTGNCPKCGSYLEITEKVDVVDQLSEICDQMGTRVEFISTDFEEGSQLLKAFGGVVAILRFNTGI
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_BACSU
Sequence: MNQWMELADRVLAGAEVTDEEALSILHCPDEDILLLMHGAFHIRKHFYGKKVKLNMIMNAKSGLCPENCGYCSQSAISKAPIESYRMVNKETLLEGAKRAHDLNIGTYCIVASGRGPSNREVDQVVDAVQEIKETYGLKICACLGLLKPEQAKRLKDAGVDRYNHNLNTSQRNHSNITTSHTYDDRVNTVEIAKESGLSPCSGAIIGMKETKQDVIDIAKSLKALDADSIPVNFLHAIDGTPLEGVNELNPLYCLKVLALFRFINPSKEIRISGGREVNLRTLQPLGLYAANSIFVGDYLTTAGQEETEDHKMLSDLGFEVESVEEMKASLSAKS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: LIPT2_MOUSE
Sequence: MSLPVVRLVWLGRVHYSELLALQEHWLRRLQADPRPGTLSGTKAGVLLVCEPAGPVYTGGLRGGLTPEETTRLRALGAEVRATGRGGLATFHGPGQLLCHPVLDLRLLGLRLRTHVAALEACAVRLCELRGLQGARARPPPYTGVWLGERKICAIGVRCGRHITSHGLALNCSTDLTWFEHIVPCGLVGTGVTSLSEALQRLVTVDEVMPSFLVAFKETFKCTLISEDSPS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes, which catalyze essential redox reactions (By similarity).  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
What are the official names of this protein?
Putative lipoyltransferase 2, mitochondrial, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: S226A_XENLA
Sequence: MSFAELLERTGGMGRFQITQVALMCFPILLMASHNLLQNFSAAIPDHKCKANDTWYQSNNTDRMGYVRLSAPLDADGQPDRCLEYVEVQWMIAGTNRTWANSSQLATRPCTEGWEYSKDEFNSTIITEWDLVCGHKNRRQLAQSVYMGGVLVGAIILGGLSDRYGRRALLIWSYFQMAVSGLCSAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTITGTLAGFSYTVGQLLLAGLAYAMRDWRWLQLCVSLPFFIFFLYSWWFPESARWLVLSGKTERAVKEMKKVAKLNGKEEEGEKITLESMRSDMIKELACAKSSYTVIDLIRTSTIRRISCALSLVWFSTSFAYYGLAMDLQNFNVSIYLIQVIFGAVDFPAKIFSTTAMIYVGRKFTQLMSLILGGVVILANSFVPHEMQTVRTGMAVFGKGCLAASFSCVFLYTTELYPTVIRQSGLGLCSTMARIGGIVAPLVKILGEYYPFLPLVIYGGAPIISGLCVFFLPETVNKPLPDTIEEVEKRIKAPKKENEMNEIVSLKKKEGMKENPVNDVL
What is the function of this protein?
Involved in the renal elimination of endogenous and exogenous organic anions.  Mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3-dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) and edaravone sulfate.  PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), indomethacin, sulindac, diclofenac, carprofen, okadaic acid, benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, bumetamide, losartan, probenecid, phenol red, urate, glutarate and alpha-ketoglutarate (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 6-A, Organic cation transporter 1-A, Renal organic anion transporter 1-A, ROAT1-A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL9_STRP8
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSIGELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISEELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKELTAEIKLAITEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SYC_CLOBJ
Sequence: MKVYNTLTNKKEEFLTLVPGEVKMYVCGPTVYNFFHIGNARTFVVFDTIRRYLEYRGYKVKFIQNFTDIDDKMIKRANEEGSTVKELGDRFIKEYYKDADDLNIERATKNPRATEFMEEIIKFVSDLIEKGYAYEIDGDVYFSTKKFNSYGKLSGQNLEELQLGARINVDERKKDPMDFAIWKSQKPGEPAWESPWGMGRPGWHIECSCMAYNLLGETIDIHAGGSDLSFPHHENEIAQSEARTGKQFAKYWLHSAFVNVNNQKMSKSLNNFFTAREILEKYDADVLRMFMLSGHYRTQINFSMELLDSTKSALDRLYNSINNLENLLDEVKNEELRDEELEYKNELQKYKEKYIEKMDDDFNTADAISVIFDLIRDVNTNVTIESSKELVKYTLDLIRELGSPLGILQESTKASLEEEIEKLIEERQKARKEKNWALADKIRDNLKERGIVLEDTPQGVRWKQI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2236_ARCFU
Sequence: MPTQAANEALAILRDASQFQWYVITLLLVVIYIYASEIHQKNYRAVFAGLAFWGMDWFNEIWNALVFHFTNYAAVWMAPGKTAYLILIGLNIEISMMFAIMGVAATKLLPEDRKAKIFGINNRIFYAIVLSAACVVVEIILNAANVLVWEYWWWNAKMPLLIFLIGYLPFFLVAYWVYDMDLVEKQAAVSFGILAIDAVLLIVFAGLMEWI
What are the official names of this protein?
Uncharacterized protein AF_2236.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIRA_BACSU
Sequence: MRSTLRKDLIELFSQAGNEFISGQKISDALGCSRTAVWKHIEELRKEGYEVEAVRRKGYRLIKKPGKLSESEIRFGLKTEVMGQHLIYHDVLSSTQKTAHELANNNAPEGTLVVADKQTAGRGRMSRVWHSQEGNGVWMSLILRPDIPLQKTPQLTLLAAVAVVQGIEEAAGIQTDIKWPNDILINGKKTVGILTEMQAEEDRVRSVIIGIGINVNQQPNDFPDELKDIATSLSQAAGEKIDRAGVIQHILLCFEKRYRDYMTHGFTPIKLLWESYALGIGTNMRARTLNGTFYGKALGIDDEGVLLLETNEGIKKIYSADIELG
What is the function of this protein?
Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
What are the official names of this protein?
Bifunctional ligase/repressor BirA, Biotin--[acetyl-CoA-carboxylase] ligase, Biotin--protein ligase, Biotin-[acetyl-CoA carboxylase] synthetase.
What is the protein family that this protein belongs to?
Belongs to the biotin--protein ligase family.
Protein: CCME_ECOBW
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: TTLL7_XENTR
Sequence: MPSLPNESDHQATCSLSLHSDLPYQPSSSIKRKVRKKKKNGAITANVVGTKYEIVRLVTEEMMFTKARDDDETANLIWNDCAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMTKMIKCQPHEYNFIPRTWIFPAEYTQFQTYIKELKKKRRQKTFIIKPANGAMGHGISLTRNGEKLQAQDHLIVQEYLEKPFLLESYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHPPSESNLSQLYMHLTNYSVNKHNENFERDETENRGSKRSIKWFTEFLRANDYDISKFWNDISDLVVKTLIVAEPHVLHAYRMCRPGQHPTSESVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDHDVKKGVLLNALKLLNIRASDKKKNLAKQKAEAQKRLYGQGSMKRLSPASSDWEKQRHTLERRKEELKERLAQVRKQISREEYENRHLGNYRRIYPPEDKLLLEKYEGLLATAFQTFLAGRAASLQREMNNPLKRMKEEDILDLLEQCELDDEKLSGKPTRPKEPRTLSSMPESTQTLKKLKNYSSHSSSNSTGSSSDTEEEEDEKEGKEKKVSYDLEEHKYKSLERSSRIHWKPPLKAARPFSNSSSPSSAASMRRSVSCPRSITALNTQSPTTDQRPFSSRISSTITRPLSGNRTNSLNRSSSSNRVPQSGTSGSVYPSISESRLDHLTKEQEEELTKQTLYALRDMRIRIPGKGVEEITHSHIDEIMDNWTYHKSKVASYWLIKLDSVKQRKVLDIVRTNIRSVLQRIWKVSDVECLHIYRSFNRVFNRLLWNHGQGLWSCFSNSGTSWETIFCKSTEVVTPQQFQCCQRLVQLCKDCLLAVYKYATDSRVAGMSPDWDDSRYLFPVVPQFTMKSSSSGVNCSSSRLPRSSILFNPRHNHY
What is the function of this protein?
Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin (PubMed:26875866, PubMed:28576883).  Mediates both ATP-dependent initiation and elongation steps of the polyglutamylation reaction (PubMed:26875866).  Preferentially modifies the beta-tubulin tail over an alpha-tail (PubMed:26875866, PubMed:28576883).  Competes with monoglycylase TTLL3 for modification site on beta-tubulin substrate, thereby creating an anticorrelation between glycylation and glutamylation reactions (PubMed:28576883).
What are the official names of this protein?
Tubulin polyglutamylase TTLL7, Tubulin--tyrosine ligase-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, dendrite. Perikaryon. Note=In cells with primary cilia, found in both cilia and basal bodies. In neuronal cells, found in dendrites and perikaryon.
Protein: TAPT1_MOUSE
Sequence: MAGVCDAAAPGEGGGGGADGPERTGRGEAEQPGGGGHGPAPQHTETLGFYESDRRREKRRGRAELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCMRIPRELEKLMFFGIFLCLDAFLYVFTLLPLRVFLALFRLLTLPCYGLRDRRLLQPAQVCDILKGVILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVIASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSSIKVQGILSYACVILFYFGLISLKILNSIVLLGKSCQYVKEAKMEEKLFNPPPASTPGKPSSKSQSKGKPSQGLSTEENLSASVTSQPGHQKENVIPLLVTSNSDQFLTTPDGDEKDITQENSELKHRSSKKDLLEIDRFTICGNRID
What is the function of this protein?
Plays a role in primary cilia formation (By similarity).  May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity).  May be involved in cartilage and bone development (By similarity).  May play a role in the differentiation of cranial neural crest cells (By similarity).
What are the official names of this protein?
Transmembrane anterior posterior transformation protein 1.
What is the protein family that this protein belongs to?
Belongs to the TAPT1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Membrane; Multi-pass membrane protein.
Protein: RL4_CORU7
Sequence: MSNLKLDVHTADGKTNGSVELPASIFDVEASVALMHQVVTAQLAAKRQGTHATKGRGEVRGGGRKPFRQKGTGRARQGSIRAPHFTGGGTVHGPQPRDYSQRTPKKMKAAALRGALSDRARHSRIHVIEELVPGQIPSTKSARSFLERLTERKQILVVLTREDLTARKSVANLPNVHALPADQLNTYDVLHADDVVFSVEALDAFIKAASGANKAEDQNTKEEAK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ACE_HUMAN
Sequence: MGAASGRRGPGLLLPLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSEVELRHS
What is the function of this protein?
Isoform produced by alternative promoter usage that is specifically expressed in spermatocytes and adult testis, and which is required for male fertility (PubMed:1651327, PubMed:1668266).  In contrast to somatic isoforms, only contains one catalytic domain (PubMed:1651327, PubMed:1668266).  Acts as a dipeptidyl carboxypeptidase that removes dipeptides from the C-terminus of substrates (PubMed:1668266, PubMed:24297181).  The identity of substrates that are needed for male fertility is unknown (By similarity).  May also have a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.  The GPIase activity was reported to be essential for the egg-binding ability of the sperm (By similarity).  This activity is however unclear and has been challenged by other groups, suggesting that it may be indirect (By similarity).
What are the official names of this protein?
Angiotensin-converting enzyme, ACE, Dipeptidyl carboxypeptidase I, Kininase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase M2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Detected in both cell membrane and cytoplasm in neurons. SUBCELLULAR LOCATION: [Angiotensin-converting enzyme, soluble form]: Secreted. SUBCELLULAR LOCATION: [Isoform Testis-specific]: Cell membrane; Single-pass type I membrane protein. Secreted. Note=The testis-specific isoform can be cleaved before the transmembrane region, releasing a soluble form.
Protein: METAA_STRZJ
Sequence: MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQMDSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLCWSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPUCD_LISM4
Sequence: MDTLKQLIDYYQTNGSYVMEEFWRHFLMSAYGVIFAAIIAIPLGVYIARKKRLAGWVIQIANIIQTIPALAMLAVLMLIMGLGTNTVVLSLFLYSLLPILKNTYTGIRNVDGALLESGKAMGMTKWQVLRLIEMPLALSVIMAGIRNALVIAIGVAAIGTFVGAGGLGDIIVRGTNATNGTAIILAGAIPTAVMAILADVLLGWVERTLNPVKNKRKPLTEAL
What is the function of this protein?
Part of the ABC transporter complex OpuCABCD involved in carnitine uptake.  Probably responsible for the translocation of the substrate across the membrane.  Involved, with BetL and GbuABC, in osmoprotection and cryoprotection of Listeria.  Can also mediate weak glycine betaine transport.
What are the official names of this protein?
Carnitine transport permease protein OpuCD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRAY_SYNY3
Sequence: MANAKSSSLPSWKNPSGKTLLILLWALALALMALLSSWADMPWLSNGKLLIALGFTALVTALIGMAVVPMLVNLKASQVIQSDGPQSHLKKAGTPTMGGIFFVPVAVAIAVVGTQFNPDVIVVGLVTLGYMAIGWVDDWQILKYKSNKGLTPKQKLFLQVAIAVIFCTWLFFYGPTEITDIRIMQFVLPLGFLFWLVATFALVAESNATNLTDGVDGLAAGTGAIAFVGLGLLVAKENPALAFFCCAMAGGCIGFVHHNHNPARVFMGDTGSLALGGSLAAVGIMTGNLWGLLLISGIFLAESLSVIAQVGYYKATKGPDGVGKRLLKMAPIHHHLELSGWTETQIVGSFYLINTLLAIVAMATA
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL13_HYDCU
Sequence: MKTFVAKPAEVKRDWYIVDAEGKTLGRMAAEIAARLRGKHKPEYTPHVDCGDYIVVINAEKIAVTGNKRTDKMYHHVTGYVGNLKSTNFETLVGSKPTRPVEFAIKGMLPRGPLGRAMLKKLKVYAGAEHPHAAQQPKELDL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: YI32_AGRT7
Sequence: MAGRSSASSALLYGPRGFDLPFSRSMRLERETPSVSATAFIANRPSATRSAAISVFLSPLWKGLRGGFRPPSSCDRACAPTPGRDPPVSSLPNSRQPARQNPRLQHLPRSRACATDKANWAPRMTASGRRYRLAGFKTLLNDCQLLLGCPPPARDITRQQFNVSIVVRHKPVLKPVLEPFCLCRLSGRNGGQFI
What are the official names of this protein?
Insertion element IS136 uncharacterized 21.2 kDa protein.
Protein: FANCC_HUMAN
Sequence: MAQDSVDLSCDYQFWMQKLSVWDQASTLETQQDTCLHVAQFQEFLRKMYEALKEMDSNTVIERFPTIGQLLAKACWNPFILAYDESQKILIWCLCCLINKEPQNSGQSKLNSWIQGVLSHILSALRFDKEVALFTQGLGYAPIDYYPGLLKNMVLSLASELRENHLNGFNTQRRMAPERVASLSRVCVPLITLTDVDPLVEALLICHGREPQEILQPEFFEAVNEAILLKKISLPMSAVVCLWLRHLPSLEKAMLHLFEKLISSERNCLRRIECFIKDSSLPQAACHPAIFRVVDEMFRCALLETDGALEIIATIQVFTQCFVEALEKASKQLRFALKTYFPYTSPSLAMVLLQDPQDIPRGHWLQTLKHISELLREAVEDQTHGSCGGPFESWFLFIHFGGWAEMVAEQLLMSAAEPPTALLWLLAFYYGPRDGRQQRAQTMVQVKAVLGHLLAMSRSSSLSAQDLQTVAGQGTDTDLRAPAQQLIRHLLLNFLLWAPGGHTIAWDVITLMAHTAEITHEIIGFLDQTLYRWNRLGIESPRSEKLARELLKELRTQV
What is the function of this protein?
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function.  May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
What are the official names of this protein?
Fanconi anemia group C protein, Protein FACC.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Protein: Y678_STRCO
Sequence: MAGNEKSRAKMEQAKGKAKEAAGRAVGNERMTAEGRAAQSKGDARQAKEKGKDVFRH
What are the official names of this protein?
UPF0337 protein SCO0678.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: PUR9_OCEIH
Sequence: MSKRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGRVKTLHPMIHGGLLGKRSNHEHLSQMEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRSAAKNFEDVLVVTGPTDYNRVLAAITSETDTYEFRQQLAAKVFRHTASYDAMIANYFLSQTEEQYPESYTVTYEKVQDLRYGENPHQQAAFYKEPIQSRPTLATAKQLHGKELSYNNIQDTNAAIEIVKEFAEPAAVAVKHMNPCGIGIGESISTAFERAYQADPTSIFGGIVACNRPVDAATAEQLSQIFLEIVVAPSFESQALEILTQKKNIRLLELDVTSDNKQSNRLTTVDGGALIQAYDAKEVSEADLEVVTNKQPTEQEINDMLFAWKAVKHVKSNAIVLAKDSQTIGVGAGQMNRIGAAEIAIKQAGDKSEGAVLASDAFFPMPDTVEAAAKAGIKAIIQPGGSKRDQDSVDVCNQFGIAMVYTKVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.