PharMolix/UniProtQA huggingface dataset:
Protein: ATG8_GIBZE
Sequence: MRSKFKDEHPFEKRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSGENTFGEA
What is the function of this protein?
Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation (By similarity).  With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton (By similarity).  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Participates also in membrane fusion events that take place in the early secretory pathway (By similarity).  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).  Moreover not only conjugation, but also subsequent ATG8-PE deconjugation is an important step required to facilitate multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, cvt vesicle membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Note=Membrane-associated through a lipid anchor (By similarity). This association needs the 2 ubiquitin- like systems required for cytoplasm to vacuole transport and autophagy (By similarity). Localizes to both the isolation membrane (IM) and the vacuole-isolation membrane contact site (VICS) during IM expansion (By similarity). The IM is a membrane sac generated from the pre- autophagosomal structure that ultimately expands to become a mature autophagosome (By similarity).
Protein: YL128_MIMIV
Sequence: MTSSIVLKFFLIATLLVIANSLPACHNGQFLKINKGPNCDDAKYENPDYVIVGGGAAGSVLLDKCISYGYKCTLIERGIDYEDEQVVSQPSGSGLVQSSNAVLLTTTYPNSNIFNKTLVITEPNIIGGSTSINGEISVFTDIENFFEEISIPGWSYLDVLPYYLNVTNSVNRPSHQGAVDVTNTLVTDPKYVAFKAAIQQVFPNIHEKLPDMNTASLNGGFPGYGPPETSVKTSFIPIGDTQVPVSGFRESAYRAYIHPIRNHPNVRIMLRSRVDKVAFDKCGETAKKVFVTYQNYQGSDSQCELKAKKGIILSAGALRTPQILMQSGVGPADHLNELGIPVVSDMPDVGQHLDDHPTVVRTFLGIIPDSSISANIDGHAYWNHLDDPNKVPNWSIQISGFYGPNFKNILNVYMDQMSRGWIKLRSTDPADTPIFNLGHFSDLEDVGPASLGFNKTNQVISNLQYIPIPGLTDVVCPSFIPNCQSNLTEYYMAAYYQFGYSGYHYTGTCAFEKVVDPNTGLVYGFDNLYVVDASVFPKAPRGNTQIGTYAISAKLADIIFGCQ
What are the official names of this protein?
Putative GMC-type oxidoreductase L128.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: RLME_YERPA
Sequence: MSNKKRSASSSRWLQEHFSDKYVIQAQKKGLRSRAWFKLDEIQQSDKLFKQGMTVVDLGAAPGGWSQYAVTQIGSKGRVIACDLLPMDPIVGVDFLQGDFRDELVLKALLERVGDKKVQVVMCDMAPNMSGTPAVDIPKSMYLVELALDMCRDVLAPGGSFLVKVFQGDGFDEYLREIRSLFTKVKIRKPDASRARSREVYIVATGRKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_STRZT
Sequence: MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRNNNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGASAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NIBA1_MOUSE
Sequence: MGGSASSQLDEGKCAYIRGKTEASIKNFSPYYSRQYSVAFCNHVRSEVEQQRDLTSQFLKTKPPLEPGTVLYEAELSQFAEDIRKWKDRYIVIKNDFAVESYESKEAYQRGAVPKSRILPAGGKVLTSEEEYSLLSDKHFPDPTASSEKNSQPFVLLPKAFPVYLWQPYLRHGYFCFHEAAEQQKFSALLNDCIRHLNHDYMKQTTFEAQAFLEAVQFFRQEKGHYGSWEMTTGDEVQVLSKLVMEELLPTLQTDLLPKLKGKKNDRKRAWFGLLEEAYNLVQHQVSEGLNALKEECRALTKDLEGTIRSDMDQIVTSKNFLTGKIRAMVAQPAEQCCGESVQPFLASILEELMGPVSSGFSEVRALFEKEVDELSQSFHATQDSAQLKEGLQQLMKLPLDSVKMEPCYTKVTLLPERLLDLQSRFRFPHVDLVVQRTQNYMQELMENAVFTFEQLLSPYLQGEASRIPVAIEKVKLRVLKQYDYDSSTIRKKIFQEALIQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENVYEEILYEILLDETLKVITEAAILKKHNLFEDNMALPSESVSSLTDLKTAMGSNQASPARRVSAILPGAPDNELPSNEVFQEPEEKKEQPGVPGSLAISASSCPSGGDGQVSVDHSAGGPLTVENTAGPLSSHLSEVEAGGTLKDEEPTCQSPEPSAVPGSLKELKKLLTVTVSVESAPVVENDIHNGTPVPQENIKEEESKIHPEASHPAAIQQDSCEEREVREKEAQPLEAEAPGVDLGILPEGRGSTSQSTSGGLTENTSCPGPIEEPFEAQEPAEKVLPAIVSTEDSPQAGGEAEHSVTVTPQEDATLSSNPICPMESNEVAQASGDQEVLGGEDSSALGMDTEQVNDTHEHACQWLVEDTLSTDILAVHDFDVSSPEQPSEEW
What is the function of this protein?
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1.  May be involved in the endoplasmic reticulum stress response.
What are the official names of this protein?
Protein Niban 1, Protein FAM129A, Protein Niban.
What is the protein family that this protein belongs to?
Belongs to the Niban family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor.
Protein: ATT_APLVA
Sequence: NNKCDIEFATSECEMRYQDCGEASSCTALIEECKTSLQEECNQASSDESSTTVRPE
What is the function of this protein?
Water-borne pheromone that attract the marine mollusk Aplysia into breeding aggregations and coordinate male and female reproductive behavior within the aggregation.
What are the official names of this protein?
Attractin.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOZ_CITBB
Sequence: MARVTVEDCLEKVDNRFLLVMLASKRVKQLFKGARPLIDNRGANKNVVVSLREIAAGKIGCEIGKKGR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL24_HELP2
Sequence: MKSEIKKNDMVKVIAGDDKGKVAKVLAVLPKTSQVVVEGCKVVKKAIKPTDDNPKGGFIHKEKPMHISNVKKA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: LIMD_DICDI
Sequence: MSNLGKCTRCQKTVYSQEGFIAVKVPFHRSCFKCEVCNWQLVLTNYKSINGKVYCANHYPVGGLSVTPEKTHTTSDDLVMKNALNAPRVETVNEQLRGGNEKPQTSTDDLVTKNALNAPKSNLVNNQVRGTSDSAPLTSADDLVTRNALKAPKSDLVNNQVRGTSEMGPQAGIDIVTANALKAPKLETMSGYQKSVQN
What is the function of this protein?
Binds to F-actin and may modulate the chemotactic response during early development and contribute to the maintenance of the strength of the actin cytoskeleton.
What are the official names of this protein?
LIM domain-containing protein D.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Protein: PANB_SYNS9
Sequence: MRPFDLIRFKQSGRPITMLTAWDCLSAALVEAAGADVVLVGDSLGMVALGHATTLPVTLDQMLHHTLAVARGFTASHDQQPLLVCDLPFLSYQCGPDLAVAAAGKLLKESSAAAVKLEGADPEIVAVVDRLVRMGIPVMGHLGLTPQAVHRLGYRRQALDPVSQDRLIEQALTLEKTGCFALVLEHVPSELAARARHELGIPVIGIGAGDDCDGQVRVTADLLGLTPHQPPFSPPQLNGRQLCIEALRGWIQEHQSSSPTTAPPQAEPDC
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP6B_THEKO
Sequence: MAEANQLFKEFKIQSVSEFFRRNAAMLGYTGKVRSLTTLVHEAVTNSLDACEEAGIPPYVRVEIEELGNEHYKVVVEDNGPGIPEKYITHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMFAQITSGKATRVITSTGNDEIIEAWVKIDVDKNEGKIVKKEKHPNPKGWRGTRIELEVKNVKYMRSKQGVFWYLKLTAIANPHAHIELIEPDGKLIVFPRSSDYIPEPPVEMKPHPKGVLTDDVYRLAKKTRRNTVRRFLIGEFSRISDKKVDELIEYIAALRLIKTVEDKKLQEQYYQKLMEGHVKAVLRAFKGYTKVVKQVAKMMEKPPEKLTWHEAEEIVEAFKYMKFLAPPTHGLRPIGEENIEKGLKGILKPEFVTAVTRPPKVYSGGIPFQVEVGIAYGGEIPAGFDLYRYANRVPLLFDAGSCVTTQAARSIDWKRYKIDDLDRAPLVLMINVVSVHVPYTGTGKQSIASVDEIYNEIRLAIMDAARRLQTYLSGKHRKLAQVKRRKTFEKYVPEIARALSILTGEPEEKIREYFIRFIESKFASAEVEEVAAEEVAENA
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: COXX_BURO0
Sequence: MQSTLSQSPGSRFSQYMALTKPRVTQLAVFCAVIGMFLATPGMVPWHVLIGGTVGIWLLAGAAFAINCLVEQKIDAMMRRTAWRPSARGEITTPQILLFSAVLGSVGAWTLYTFTNPLTMWLTIATFVGYAVIYTLLLKPMTPQNIVIGGASGAMPPALGWAAVTGAVPGDAWILVLIIFVWTPPHFWVLALYRRKDYENAGLPMLPVTHGEKFTRLHILLYTVILFAVTLMPFISGMSGAVYLTSAVLLGAVFLAYAWKIHRDYSDELARKAFRYSIVYLSLLFAALLVDHYARPLLGV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
Protein: PPE63_MYCTO
Sequence: MADFLTLSPEVNSARMYAGGGPGSLSAAAAAWDELAAELWLAAASFESVCSGLADRWWQGPSSRMMAAQAARHTGWLAAAATQAEGAASQAQTMALAYEAAFAATVHPALVAANRALVAWLAGSNVFGQNTPAIAAAEAIYEQMWAQDVVAMLNYHAVASAVGARLRPWQQLLHELPRRLGGEHSDSTNTELANPSSTTTRITVPGASPVHAATLLPFIGRLLAARYAELNTAIGTNWFPGTTPEVVSYPATIGVLSGSLGAVDANQSIAIGQQMLHNEILAATASGQPVTVAGLSMGSMVIDRELAYLAIDPNAPPSSALTFVELAGPERGLAQTYLPVGTTIPIAGYTVGNAPESQYNTSVVYSQYDIWADPPDRPWNLLAGANALMGAAYFHDLTAYAAPQQGIEIAAVTSSLGGTTTTYMIPSPTLPLLLPLKQIGVPDWIVGGLNNVLKPLVDAGYSQYAPTAGPYFSHGNLVW
What are the official names of this protein?
Uncharacterized PPE family protein PPE63.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: SAD2H_ARATH
Sequence: MDLPSLALIVGAAAFSPNPDERRAAEQSLNQLQHTPQHLIRILQIIVDGGSDLSVRQSASIHFKNFIAKHWEPHSGDQNIILPSDKNVVRNQILVFVSQVPPILRVQMGECLKTIIYADYPEQWPELLDWVKQNLQKPQVYGALFVLRILSSKYEFKSDEDRAPIHRVVEETFPHLLNIFNNLVHVENPSLEVADHIKLICKIFWSCIYLELPRPLFDPNFFNAWMGLFLNILERPVPVEGQPEDPELRKSWGWWKAKKWIAHILNRLYTRFGDLKLQNPDNKAFAQMFQINYAAKILECHLKLLNAIRIGGYLPDRVINLILQYLSNSISKSSMYNLLQPHLNTLLFEIVFPLMCFNDNDQMLWDEDPHEYVRKGYDIIEDLYSPRTASMDFVTELVRKRGKENFPKFIQFVVDIFKRYNEASLENKPYRLKDGALLAVGTLCDKLRQTEPYKSELENMLVQHVFPEFSSPAGHLRAKAAWVAGQYANIDFSDQSNFSKALHCVISGMCDLELPVRVDSVFALRSFIEACKDLDEIRPVLPQLLDEFFKLMKEVENEDLAFTLETIVYKFGEEISPYALGLCQNLASAFWRCIDTDNGDDETDDAGALAAVGCLRAISTILESISSLPHLYGQIEPQLLPIMRKMLTTDGQDVFEEVLEIVSYITTFSPTISLEMWSLWPLMMEALVDWAIDFFPNILVPLHNYISRGTGHYLTCKEPDYQQNLWNVISVLMANKNIDDSDLEPAPKLLGIVLQTCKGQVDQWVEPYLRITLDRLRGAEKSSFKCLLVEVVANAFYYNTPLALGILQRFGIATEIFTLWFQMLQEKKKSGARSNFKREHDKKVCILGLTSLFSLPAGQLPGEVLPHVFRALLELLVAYKDQLAEAAKAEEEEEDEDGDDDDMDEFQTDDEDEDGDDENPDETDGSTLRKLAAQAKDFRSYSDDDDFSDDDFSDDEELESPIDEVDPFVLFMDAVTAMQVSDSPRFQSLTQTLDPHYHGLASTIAQHTELRRAEILKEKLEKQSSATVAS
What is the function of this protein?
Functions probably in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with other importin subunits.
What are the official names of this protein?
Importin beta-like SAD2 homolog.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYGA_DESVH
Sequence: MHFQNVILTLQNYWASRGCVITQPIDVECGAGTFNPSTFLRVIGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYFQFQVILKPSPDNVQELYLGSLRALGIDPAAHDIRFVEDDWESPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDLAPTSVEITYGLERLCMYLQGKESVYDLDWNEHVTYGDIYHQNEVEQSKYNFERSDAAMLLHAFNAYETECRRLTEEGLLWPAYDYCLKCSHTFNLLDARGAISITERTGYIGRVRYLASGVARLYAAQREQLGYPMLRK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S1PR5_HUMAN
Sequence: MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
What is the function of this protein?
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P).  S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.  Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity).  May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
What are the official names of this protein?
Sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPO4_PSET1
Sequence: MKKFIHIDMDCFYAAVEMRDNPKLANVPLAIGGNSRRGVLSTANYIAREYGVRSAMSNYHAKQLCPDLVIVPGRMAVYKDVSTQIRAVFSRYTDLIEPLSLDEAYLDVTHSEQCKGSATLIAQQIRADIYNATGLTASAGIAPIKFIAKIASDENKPNGQFVVLPDQVDAFLAQLPLGKIPGVGKVTLEKLNLKGLYTGQDVRKKGVNWMQQHVGNFGVSLYQKCAGEHIGRVSTERVRKSLSVEHTYEYNKNSLQECLEQLPSLLEELTTRLNKQQLQNQVNKLSVKVKFANFVVTSADQAHQQLNSDIFSELLAKAYQRGLQQPVRLLGIGVGIKNQPQHNLQLSILDM
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_AERS4
Sequence: MASKKIDRLSFDATLEELETIVHQLEQGSLPLEEALKQFEQGVHLVRAGQQKLEQAEQKIQILLTQADGTEQAVPFQPEQGEE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA57_MOUSE
Sequence: MSTVVAQALHVFGLRPHVTNNVFFFDEQIIIFPSGNHCVKYNIDQKWQKFIAGSDKSQGMLALAISPNRRYLAISETVQEKPAVTIYELSSIPCRKRKVLNNFDFQVQKFTSMAFSPDSKYLLTQTSPPDSNLVYWLWEKQKVMAIIKADSQNNPIYQVSISSQDNSQVCITGSGVFKLLRFAEGTLKQINFQRGESSNYLAHAWVSEDRVIVGTDTGKLFLFESGDQRWETSIMVKESTSSRSLEVIQESESLIEFPPLSSPVSSVERMDITTNTQQQAMPQVFAIAAYSKGFACSAGPGRVLLFEKVEEKDFYRESREIRIPTDQQSNDPSQSDKQDVLCLCFSPSEETLIASTNKNQLYSITMSLTEISKGEAAHFEYLLYPLHSASITGLDTCIRKPLIATCSLDRSVRIWNYESNTLELYKEYQEEAYTVSLHPSGHYIVVGFADKLRLMNLLIDDIRPFKEYSVRGCKECSFSNGGHLFAAVNGNVIHIFTTTSLENINILKGHTGKIRSLVWNLDDSKLVSAGTDGAVYEWNLSTGKRETECVLKSCSYNSVTTSPDAKVIFAVGSDQTLKEISDSLILREIPAFDVIYTSITISHSGRMIFVGTSVGTIRAMKYPLSLQKEYNEYQAHAGPVMKMLLTFDDQFLLTVGEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQIMLELKTRVEELKMENEYQLRLKDMNYTEKIKELTDKFIQEMESLKTKNQVLKTEKEKQDISHRERLEELVDKQTRELQDLECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTGLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYERKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIELLKSEQMKLQGIIRSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKVMKEQIQEMEAELERFHKQNTQLELNITELLQKLRATDQEMRKEQQKERDLEALVRRFKTDLHNCVAYIQEPGLLKEKIRGLFEKYVQRADMVEIAGLNSDLQQEYARQREHLERNLATLKKKVIKEGELHRTDYVRIMQENVSLIKEINELRRELKLTRSQIYDLESALKVSKKTRSQEVPESVISKDVVGSTSTMRLNEQEETGRIIEMQRLEIRRLRDQIQEQEQVPGFHTIAGVRLPSIVDSDVDFEVHTK
What are the official names of this protein?
Cilia- and flagella-associated protein 57, WD repeat-containing protein 65.
Protein: COMB_PROMA
Sequence: MELSYFHVAKDVPSGIKPETSVVIDVLRATTTIACALNNGAEAVQTFADLDNLKEQASCWPLSKRLLLGERGGKKIDGFDLGNSPLAVTSNVVKGKRLFMSTTNGTRSLERVKESKSLYTMSFINRKAVAEKLISNQSKSVLILGSGWEGAYSLEDSLAAGALASFLLNKNPNSVHILNDELSAAVALWSCWENNIEGCLRNATHGKRLERLGNHDDDFTCCSELDKICVVPTQREKGVLCSL
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: RL6_IDILO
Sequence: MSRVAKAPIEIPAGVEVTLNGQEVTIKGAQGSLSRVVNDAVELVKDESELRTNAREGVANSTAQAGTARALLQNMVVGVTKGFERKLQLIGVGYRAQAQGKKLNLTLGFSHPVEFEIPEGITIDTPTQTEVVVKGADKQLVGQVAANIRAYRKPEPYKGKGVRYADEQVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL20_METI4
Sequence: MARATNAPQSRKRRKRLLRDARGFRGRRSKLFRYAKDALYKARYWSYRDRKNRKREFRALWIQRINAACRKRGMTYSRFMEALRKAGIGVNRKMLAELAVRSQEDFDQIFKLAKEGNLAS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL5_CENSY
Sequence: MAGDMRKITLEKVVLNMGVGQSGNAVEVAKRALGEISGKKPCGRDAHETQRDFGVRKGEPIGAAVTIRGEDAGALARRLFEAKGGQVKGRSFDDFGNFSFGIGEHIDIPGIKYDPGIGILGLDVCMTLSRPGYGIRKRSKHKARVGRSHRITATEAKDFVVREFGVEIV
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RSMG_STRPB
Sequence: MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAITEENEVYLKHFYDSIAPILQAFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDSLNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELTIPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKKKETPNKYPRKAGLPNKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX12_CAEEL
Sequence: MSTTIRASQLASSISPKTEEKQPSVFDIIAQENLATSIRPALQHLVKYLAFFKPKTFLSVHRNFDEYYIIFDLILQNHYLRNYGASFTENFYSMKRIASGTGNPPNDGRERIMSLITLVGWPYVENKLNQLYDRLKEVYECRSWSSINGMKAKCQKMFVIIWPYIKTALKAVKSALQLAYILNRSSIHSPWLYFSGVILKHLTPEDLEAFNAVPLHLQTGYQISRGTLNEHIHLRFFNRIWRFILGLPGIVSRLFAYGLFFVQFLDYMYNTDLAKLTKTGLDGAIPSPPHKMIISESEILSLDTNKCPICLKKRVNDTALFVSGYVFCYTCINQYVNTYNKCPVTGCPANVQHLIRLFV
What is the function of this protein?
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5/prx-5 receptor from peroxisomes to the cytosol, thereby promoting PEX5/prx-5 recycling (By similarity).  The retrotranslocation channel is composed of PEX2/prx-2, PEX10/prx-10 and PEX12/prx-12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5/prx-5 through the peroxisomal membrane (By similarity).  PEX12/prx-12 also regulates PEX5/prx-5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10/prx-10 (By similarity).  When PEX5 recycling is compromised, PEX12/prx-12 stimulates PEX10-mediated polyubiquitination of PEX5/prx-5, leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Peroxisome assembly protein 12, Peroxin-12.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.