PharMolix/UniProtQA huggingface dataset:
Protein: NUOK_SALRD
Sequence: MDVAPNWYLALSAVLFTIGTFGVLFRRNAIVVLMSVELMLNAVNLTLVTFSQSMGDPSGQLLVFFSIAVAAAEAAVGLAIVIAIFRSQVTVDITEINLFKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMA_LEPBL
Sequence: MSKGKIIVAMSGGVDSAVTAGLLMEEGYEVIGVNLRTWEYEAPVCDTTKKSCCSPEDIRDARDVGLSLKIPFYVVKMEKVFQEKVIDRFIDDYQHGKTPNPCVECNTFVKFGALFEKAKALGIDKIATGHYARIVRNGERYAISNGVDIGKNQAYYLYGLSQENLKNVTFPLGGMTKPEVREIARRMGLSVADKAESQEICFIPENDYRKFLEKKHVEFTPGFFKLRDGRIIGKHKGRENFTIGQRKGLGIAWRNPLYVIAIEDDGSVILGEENETYAESFSVIDVNYQGFAPLGEGESFECRVQVRYRHTPIRCRITKMNEDLVVNPLEEVRGVTPGQSAVFYPLNSDYLLLGGIIRKGSIRMQVAKEESAIAFRS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_ENT38
Sequence: MSQVILDLQLACEDNSGLPEESQFQKWLDAVIPQFQEESEVTIRVVDEAESHELNLTYRGKDKPTNVLSFPFEAPPGIELPLLGDLIICRQVVEQEAKEQQKPLDAHWAHMVIHGSLHLLGYDHIEDEEAEEMESLETEIMLALGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G1092_BACFN
Sequence: MKTPSQTHVLGLAHPPLPMVRLAFIGLGNRGVLTLQRYLQIEGVEIKALCEIREGNLVKAQKILREAGYPQPDGYTGPDGWKRMCERDDIDLVFICTDWLTHTPMAVYSMEHGKHVAIEVPAAMTVEECWKLVDTAEKTRQHCMMLENCCYDPFALTTLNMAQQGVFGEITHVEGAYIHDLRSIYFADESKGGFHNHWGKKYSIEHTGNPYPTHGLGPVCQILNIHRGDRMNYLVSLSSLQAGMTEYARKNFGADSPEARQKYLLGDMNTTLIQTVKGKSIMIQYNVVTPRPYSRLHTVCGTKGFAQKYPVPSIALEPDAGSPLEGKALEEIMERYKHPFTATFGTEAHRRNLPNEMNYVMDCRLIYCLRNGLPLDMDVYDAAEWSCITELSEQSVLNGSIPVEIPDFTRGAWKKCHISRTSDLY
What is the function of this protein?
Glycosidase that has specific alpha-N-acetylgalactosaminidase activity.
What are the official names of this protein?
Alpha-N-acetylgalactosaminidase, Glycosyl hydrolase family 109 protein.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: PNP_RUMCH
Sequence: MFKSFSMELAGRTLTVETGKLAQLANGSALIRYGDTVIMSSATASAAPRDGIDFFPLSVDYEERLYAVGKIPGGFIKREGKPSEKAILTSRVIDRPIRPLFPKDLRNDVAVVNTVMSVEQDNSPEIAAMIGASVAISISDIPFNGPIGGVVLGLVDGEVIINPNEEQRAKSKMYVTLAGTKEKITMIEAGADIVPDDVMFDAIKKGHEEIKKICDFINGIVKEVGKAKFTYESADVPADLFEVVKEFAYDKMRIAVLATDKQDRDAKVSQLTEETQAALAEQFPEMESKINDALYKLEKKVVREYILKEGKRIDGRRLDEIRTLSAEVGILPRTHGSGLFERGQTQVLTTVTLGAMGDVQMLDGIDTEETKRYMHHYNFPGYSVGEAKTSRGPGRREIGHGALAERSLVPVIPTETEFPYAFRLVSEVLMSNGSTSQGSVCGSTLALMDAGVPIKAPVAGISAGLVIDEENPDNFVTFMDIQGIEDFFGDMDFKVAGTTEGITAIQMDIKVDGLSYEIIRQAFELTRMGRLQIINDVILKAIPQPRKELSEYAPKIITTNIDPEKIRDVIGPGGKMINKIIAETGVKIDIEEDGRVYILTPDSAAAQKALKIIQGIAKDIEPGEVYLGKVVRITTFGAFVEILPGKDGLVHISKLDKKRVEKVEDVVSIGDEILVKVTEIDKQGRINLSRKDAMAEENTTEEK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIT_FSVHZ
Sequence: EEINGNNYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEVALYKNLLQSKESSCNDSTNEYMDMKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDGELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQKNKNE
What are the official names of this protein?
Tyrosine-protein kinase transforming protein kit.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Protein: NRDR_XYLFM
Sequence: MYCLFCQHTDTRVIDSRVSEDGATIRRRRECEACGERFSTLETIELKLPVIIKKDGGREAFDGRKLRTSFDRALQKRPVAEERIEMAMRAVIHRLRMAGEREVPSIVVGECVMAELRKLDHVGYVRFASVYRSFQDVADFREEIEKLESELLVSREQLPLLEAAMESMGHPSIDQGGKHGA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: FLII_PSEAE
Sequence: MRLERTSFARRLEGYTEAVSLPAQPVVEGRLLRMVGLTLEAEGLQAAVGSRCNVINESGYHPVQVEAEVMGFSGSKVYLMPVGSLAGIAPGARVVPLPDTGRLPMGMSMLGRVLDGAGRALDGKGGMRAEDWVPMDGPTINPLKRHPISEPLDVGIRSINGLLTVGRGQRLGLFAGTGVGKSVLLGMMTRFTRADIIVVGLIGERGREVKEFIDEILGEEGLKRSVVVASPADDAPLMRLRAAQYCTRIAEYFRDKGKNVLLLMDSLTRYAQAQREIALAIGEPPATKGYPPSVFAKLPKLVERAGNAEAGGGSITAFYTVLSEGDDQQDPIADAARGVLDGHFVLSRRLAEEGHYPAIDIEASISRVMPQVVEAEHLRDAQRFKQLWSRYQQSRDLISVGAYVAGGDPETDLAIARFPVMRQFLRQGLDESESLAESRARLASLLAGGQA
What is the function of this protein?
Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.
What are the official names of this protein?
Flagellum-specific ATP synthase.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_SHEB8
Sequence: MNRPERLQPGVKLRDADKVSRIPVKIVPSERDTMLRKPDWLRVKLPASNQRILEIKQALRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLKPDAEEPVKLAQTIRDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRKLNPDIKIETLVPDFRGRIDAALDILSTEPPDVFNHNLETAPMHYRKARPGANYQWSLDLLKRFKERHPNVPTKSGLMMGLGETNDEIAQVLRDLRAHKVEMLTLGQYLQPSKFHLPVERYVPPAEFDELKALADELGFTHAACGPLVRSSYHADLQAQGKEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHBG_YERPG
Sequence: MEKLLIVNADDFGLCKGQNYGIIDAFRNGVVSSTTAMMNSVDINHATELSAQYPALPVGMHFVLTFGRPLTAMPSLTDANGELGKWLWQRAGAGTLDLNEIAQELECQFERFSAVFGRPPTHIDSHHHVHMLPQIYPLVAAFAREKSLPLRIDRHEVQQHGLTLDNPRSSEWFNAGFYGENLSEPSFLQLLEHADQQGVNSLEIMCHPAFIDQTLMTSGYCYPRLTELAILTSPTLKPAIAQRGYRLGSFLDC
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGD_SHIDY
Sequence: AVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQTFTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAFLPANLIQAQRDYFGAHTYKRI
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: GPDA_RICAE
Sequence: MNKFKNIAVYGGGSFGTSLASLAAQNCNNVTLFLRDEAIAKEILHNKTNVKYLGDIKLPAHLQATTNLDIIKDFELIIIALPSYAFDDSIKLLKTHSISKDNTLLIATKGFARNPTALFSDRLKTLLPYNPTAFFVGPNLAKELAKNLPASASIASLDIDIANKIAYNLSSKIFTTNVSSDIVTLQVAGALKNIFAIKSGIDLARKQGENARATLIVAALKEIAILSKALGGMQKNSDILLEGVVGDLVLTCYSLGSRNTKFGYELGISSDKQKFLQEYKELVEGREALKLVLDLIKKYNLHMPIISEVASCVIPYVMPAFAGMT
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PI42B_MOUSE
Sequence: MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEEEECENDGVGGSLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT
What is the function of this protein?
Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.  Preferentially utilizes GTP, rather than ATP, for PI(5)P phosphorylation and its activity reflects changes in direct proportion to the physiological GTP concentration.  Its GTP-sensing activity is critical for metabolic adaptation.  In collaboration with PIP4K2A, has a role in mediating autophagy in times of nutrient stress (PubMed:29727621).  Required for autophagosome-lysosome fusion and the regulation of cellular lipid metabolism (PubMed:29727621).  PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism.  They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta, Diphosphoinositide kinase 2-beta, Phosphatidylinositol 5-phosphate 4-kinase type II beta, PI(5)P 4-kinase type II beta, PIP4KII-beta, PtdIns(5)P-4-kinase isoform 2-beta.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Nucleus. Cytoplasm. Note=Associated with the plasma membrane and the endoplasmic reticulum.
Protein: TUBY_CBCP
Sequence: MNEESTRYVDVNYSDLDKELTYTTSEVAEILNENESTIRYWCDCFSDYIHIEREGRNRKFTKSNIDDLAFTKELLKKERLTIKQAQKRWEHIKTQPSQNTKVISTTETTSQENVLNEQALLKLEEIKKQFLNDISTQINNTISQQLSTALNAHNEALEQTKVELKDYISATIEDKLEANISNLKAHIDATTENTNKQIHQIYDKDVELVNDLKKHMEERKQQNEEQNNKKGFFGKLFKR
What is the function of this protein?
A probable TubZ filament regulator that is part of the type III partition system presumably used to ensure correct segregation of this bacteriophage.  Binds to TubZ in the presence of GTP and Mg(2+), and to TubZ-TubR-tubC (tubC is the centromere-like site).  The latter complex is reshaped from large bundles to rings by TubY (PubMed:22538818).  Modifies TubZ filaments formed in the presence of GDP to make them thinner and more flexible; in GDP and lacking the last 8 residues of TubZ makes rings without TubT-tubC (PubMed:28230082).
What are the official names of this protein?
Regulator protein TubY.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: YH7J_SCHPO
Sequence: MCTFVFESLCAMISTLKVNKIERGYWFIQCLRYCFIYIIKKQHRQADLPRNFGMRSKALYIGRSVGKWIETFCLDSNYSTHVYSLWAKSFLIIQFENVDPFVDHF
What are the official names of this protein?
Uncharacterized protein C16G5.19.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NCAP_PIV5
Sequence: MSSVLKAYERFTLTQELQDQSEEGTIPPTTLKPVIRVFILTSNNPELRSRLLLFCLRIVLSNGARDSHRFGALLTMFSLPSATMLNHVKLADQSPEADIERVEIDGFEEGSFRLIPNARSGMSRGEINAYAALAEDLPDTLNHATPFVDSEVEGTAWDEIETFLDMCYSVLMQAWIVTCKCMTAPDQPAASIEKRLQKYRQQGRINPRYLLQPEARRIIQNVIRKGMVVRHFLTFELQLARAQSLVSNRYYAMVGDVGKYIENCGMGGFFLTLKYALGTRWPTLALAAFSGELTKLKSLMALYQTLGEQARYLALLESPHLMDFAAANYPLLYSYAMGIGYVLDVNMRNYAFSRSYMNKTYFQLGMETARKQQGAVDMRMAEDLGLTQAERTEMANTLAKLTTANRGADTRGGVNPFSSVTGTTQVPAAATGDTLESYMAADRLRQRYADAGTHDDEMPPLEEEEEDDTSAGPRTGPTLEQVALDIQNAAVGAPIHTDDLNAALGDLDI
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: DCD_RICB8
Sequence: MSIMSDKWIREAVINHKMIEPFAEKQVRVKDSEKIISYGLSSYGYDARVSNEFKIFTNINSTMVDPKNFDKYNLVDREVDVCIIPPNSFALGRTVEYFKIPRDVLVICVGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGACQFLFLKGDQICDLSYADRQGKYMKQLGVTLPLT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ZAPB_SODGM
Sequence: MAFEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQQAQNNRESLVNENEQLRQEQNVWQERLRGLLSKMDEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: RLMM_SALA4
Sequence: MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIYECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYTGYSLAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVCDMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNAQIQARQLYHDREEVTVHVRRLWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_ERWT9
Sequence: MFLPQEIIRKKRDGHALSDEEIRSFINGVRDNSVSEGQIAALAMAIWFRDITLPERVALTMAMRDSGSVLCWKGLDLNGPVVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPSDDRFREIIKQVGIAIVGQTRSLAPADKRFYATRDITATVDSIPLIAASILGKKLAEGLDALVMDVKVGSGALMPTLEQSEALAQAIFGVANGAGCKTTVLLTDMNQPLASSAGNALEVREAVQFLTGEYRNPRLLEVTMALCREMLLSGGLAQSDAEAQAKLQAVLDNGAAAEAFARMVAAQQGPADFIERIDSYLPAPMLSKAVYATTSGIVSTMDTRALGMAVVALGGGRRRASDSIDYSVGLSHLVQPGDKVDGERPLAVIHAASEASWQQAAQAVQHAVMVGQQQPASTAVIYRRISQ
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: LGUL_SALTI
Sequence: MRLLHTMLRVGDLQRSIAFYTNVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNWGVESYDMGNAYGHIALSVDNAAEACERIRQNGGNVTREAGPVKGGSTIIAFVEDPDGYKIELIEAKDAGRGLGN
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
What are the official names of this protein?
Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: NU2M_CYPCA
Sequence: MNPYRRATLLCSVGLGTTLTFASSHWLLAWMGLEINTLAITPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWMTGEWSINDLSNPIASTMFMAALALKIGLAPMHFWMPEVLQGLDLLTGLILSTWQKLAPLALIIQTAQTIDPLLLTLLGISSTLVGGWGGLNQTQLRKILAYSSIAHMGWMIIVIQYAPQLTLIALGTYIIMTSAAFLTLKMSLTTKISTLATTWSKSPILTSTTALVLLSLGGLPPLTGFMPKWLILQELTKQDLPIIATAMALTALISLYFYLRLLYAMTLTISPNMINSTTPWRTQTTQTSLPLALFTTAALGLLPMAPAILMLTT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IF1_BRUSU
Sequence: MAKEEVLEFPGVVTELLPNAMFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKGRITYRLK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIH_ECOLI
Sequence: MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMALLSPAASGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKRKTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQPLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGIDKIGLGALIGLSDNWRVDSYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMDERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHPELEQFSPHDDRRPEAVAAALTAQGLQPVWKDWDSYLGRASQRL
What is the function of this protein?
Catalyzes the radical-mediated cleavage of tyrosine to 2-iminoacetate and 4-cresol.
What are the official names of this protein?
2-iminoacetate synthase, Dehydroglycine synthase, Tyrosine lyase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. ThiH family.
Protein: TBA_NEOCA
Sequence: MREVISIHVGQAGIQIGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRCVFLDLEPTVVDEVRTGTYRHLFHPEQLISGKEDAANNFARGHYTIGKEIVDLSLDRIRKLADNCTGLQGFLMFNAVGGGTGSGLGCLLLERLSVDYGKKSKLNFCSWPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPASMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRMDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIETAEGEGEEEGYGDEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain, Alpha-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MRD1_ASHGO
Sequence: MSRVIVKGLPIYLEEARLRAHFLKRLQQQGRGSEDQITDVKIVKDKSGNSRRFAFIGYRSEQDAFDAIEYFNGSFIDTARIEVAMAKSFADPRVPTPMREKRREALKRLREREDRILAEKRQKQTKPQHGIDAEISKNKQLQEFIETMNPKMAAAAANPMARAAEQPASANPLLSALHGAEDDEEVDMFQLSEQESDDEYTDLHQRPQSAEEDELEEPAVGQDLDAAPAPDAAEDGMATNQEVSDLEWLKNRRIRIRDGEDAEAAPAPQEQAAEEPAEQEVPQEDEVSAEEAALTKIRATGRLFLRNILYDATEEDFKQLFSPYGELEEVHVAVDTRTGQSKGFAYVLFKDPEHAANAYIELDKQIFQGRLLHILPADAKKTHRLDEFDLKNLPLKKQRELKRKATAAQQTFSWNSLFMNQDAVLSSVAAKLGMEKSQLIDPENSGSAVKQALAEAHVIGDVRKYFEARGVDLTQFEKFKKVTERDDRIILVKNFPHGTTREELAELFLPFGKIERLLMPPSGTIAIIQYRDVPAARGAFTKLSYKRFKEAILYLEKGPKDCFSREPRGDELLEGDAAPEDVKEIKKSVEDVMDADSKTPSSEATAIDGPTVSIFVKNLNFSTTSAQLAEKFKPFSGFVVAQVKTKPDPKNSDKKLSMGFGFIEFRTKEQAGAVIAAMDGAVIDGHKIQLKISHKQSSLPKTSKGSKKKISGKIIVKNLPFEATRKDVFELFSSFGQLKSVRVPKKFDKSARGFAFVEFLLPSEAENAMDQLQGVHLLGRRLVMQYAEQESDDVEEQISKMTMKMKKQAAVSKMGALRNSGKRKIDMSDDENDGLNGF
What is the function of this protein?
Involved in pre-rRNA processing.
What are the official names of this protein?
Multiple RNA-binding domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM MRD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_CERDE
Sequence: MKNVTDSFVSLGDWPYAGSFAFNTDILATNPINLSVVLGVLIFFGKGVLSDLLDNRKQKILSSIRNSEELRAKAIEQLEKARARLRKVEIEADKFRVNGYSEIEREKGNLINSTYENLQRLENYKNEAIQFEQQRTINQVRQRVFQQALQEALETLNSCLNSELHLRTISANIVMLGVMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.