PharMolix/UniProtQA huggingface dataset:
Protein: RL13_DESDA
Sequence: MKTFSPTPKDINRQWFVVDAQDQVLGRLASQIAHRLRGKHKPEFAPHMDNGDFIVVVNCEKIKVTGNKLADKKYYRHSGWVGGLKTTILGDVLADKPSRALMAAVKGMLPKNRLGRAMLKKLKIYAGPEHPHTAQNPQPLTLPH
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS6_CHRSD
Sequence: MRHYEIVFMVHPDQSEQVPAMVERYTGLVTENGGTVHRLEDWGRRHLAYPINKIHKAHYVLMNIECSGETLDEIENIFRFNDAIIRSLVVRCKEAITEASPMMKPAEEKPRRREEKSERPRTERNEEAPADAEAN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: QUEA_PROMP
Sequence: MNFEIHNEEIDHKLEAYDYILDETLIANKPSKVRHESRLMIVRDSSLEEDFTTNKYTKNLLDELRKGDLVVVNDTKVMKARLKVELENGKLVELLVLEKADQSTWLCLARPAKKLKINSQLNLKSSLAKDIKLHISGTDKETGGRFIKFPENINDLISMNNLLDIYGETPLPPYIKSAEEESFHENSYQTEYASNPGAVAAPTAGLHLSKSLISNLKKKGILVMPITLHVGYGTFKPIDQEDLSNLKLHKEWVRVSSEVVEEIKRVKKTDRRVIAIGTTSVRALESCYSYEMGDLIPIDKYVDLVIKPGYKFKVVDGLLTNFHLPKSSLLLLVSAMIGRERLLNLYKKAIREKFRFFSYGDAMYISPDSFLVKK
What is the function of this protein?
Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step.  The ribosyl moiety of AdoMet is transferred and isomerized to the epoxycyclopentane residue of oQ (By similarity).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_CUPTR
Sequence: MTQVAKNDHRLMQVLLAPVVSEKATLVADKNEQVVFEVARDANKAEVKAAVELLFKVEVQSVQILNQKGKQKRFGRFMGRRNHVKKAYVSLKPGQEINFEAEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: METK_YERPP
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEVTTNAWVDIEEITRRTIREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRENPLEQGAGDQGLMFGYATNETSVLMPAPITYAHRLVERQAEVRKNGALPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEDINQKDLHEAVMEEIIKPVLPAEWITAHTKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVEAFGTEKIPADQLTLLVREFFDLRPYGLIKMLDLLHPIYRETAAYGHFGREHFPWEKTDKAALLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_DROAI
Sequence: MTIRPAYRPKIIKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHAVSSKKRKEIVERAKQLSIRLTNPNGRLRSQENE
What are the official names of this protein?
60S ribosomal protein L32, Ribosomal protein 49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: NHP6_NEUCR
Sequence: MPKAAAKSKTTGKVEKRRAKKDPNAPKRGLSAYMFFANEQRENVREENPGVSFGQVGKILGERWKALSDKQRAPYEAKAAADKKRYEDEKQAYNAEADEEESS
What is the function of this protein?
DNA-binding protein that induces severe bending of DNA.  Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
What are the official names of this protein?
Non-histone chromosomal protein 6.
What is the protein family that this protein belongs to?
Belongs to the NHP6 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HPRK_CHLCH
Sequence: MIFDQKGIRKRSITVAYFYNTISQKCCDLKLRRVNNVDEQKRRIYERDLHRPGLALAGFTNLFTYKRVQIFGNTETRFLNHLDDEKERNRLFENFVRFKIPCIILTSNNKLPESLIEMATRAEIPVYSTRCSSTKAIYNITDFLDDQFSIYQQYHGSMVDVYGVGVLLVGKSGLGKSEVALDLIERGHGLVADDAVVIRRKGESTTLMARRNNIIDHFMEIRGLGVVDMKANFGIRAIREQKEVQVVAELMHWDSDTEYERLGLDAKSTKILGVELPLVQLPILPGKNITVIIEVVALNFLLKRYSNYVAAEALHSRISQVINSERTNFDGDE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: KATG_RHILP
Sequence: MDNPTDSAGKCPVAHGNTPRSRSNRDWWPDQLNVQILHHNSGRADPLGQAFDYAEEFKKLHLHGLKKDLHALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRITDGRGGAGQGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGNRISWADLLILTGNVALESMGFKTFGFAGGRADVWEPEELFWGPEGTWLGDERYSGERELAEPLGAVQMGFIYVNPEGPNGNSDPLASARDIRETFARMAMNDEETVALIAGGHTFGKKHGAGEPFLIGPEPEGGAIEDQGLGWKSSFGTGVGKDAITAGLEVTWSQTPTKWSNYFFENLFAFEWELTTSPAGAKQWQAKNAEASIPDAYDASKRHLPTMLTSDLALRFDPTYEKISRHFLENPGEFADAFARAWFKLTHRDMGPKVRYLGPEVPAEDLIWQDVIPAVDHPLVDDKDIAELKEKVLATGLTVQELVSTAWASASTFRGSDKRGGANGARVRLAPQKDWDANQPAQLAKVLGVLESIQKDFNAAQTGAKKISLADLIVLAGAAGVEKAAAAGGNAVSVPFTPGRIDASEAQTDAHSFAALEPRIDGFRNYLNGKRHQFMKPEEALVDRAQLLTLTGPEMTALVGGLRVLKAGAPEHGVFTSRPETLTNDFFVNLLDMGTQWVPVAGKEGFYEGRDRKTGAAKWTGTRVDLIFGSHSQLRAFAEVYGQADAKGKFVNDFVAAWNKVMNADRFDLV
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: AROC_BURP1
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMALTEADVQLELDRRKPGTSRHVTQRQEPDQVEILSGVFEGVTTGAPIALLIRNTDQRSKDYGNIAETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPVVGAGAIAKKWLRERFGVEVRGYMSALGEIEIPFVDWSHVRENPFFAPNADIVPQLEGYMDALRKDGDSIGARIDVVASGVPVGWGEPLFDRLDADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPDGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITRAGEPAVVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVSSATPRIAARAPDAQ
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RBFA_STAA2
Sequence: MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDLSQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGNKIERMIQDLHKQDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_THEP1
Sequence: MAVIYYDKDADLELIRDKKIAIIGYGSQGHAHALNLKDSGLNVVVGLREGSKSWKKAEEQGLTVKAIEEAAKEADIIMMLIPDENQPEIYKKYIEKHLTEGKMLMFAHGFNIHYHQIIPPKNVDVTMIAPKSPGHIVRREYVEGRGVPALVAVYQDYTGKAKDIALAYAKGIGVTRAGVIETTFKEETETDLFGEQAVLCGGVTALIKAGFETLVEAGYQPEIAYFECLNELKLIVDLIYEGGLSFMRYSVSNTAEYGDYISQEKIVTKEVRENMKQMLKDIQTGKFAKDWILENQAGRPYFYTMRKKESEHLIEKVGKELRKMMPWLKERNVDEE
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PUR7_SHESA
Sequence: MSLADSVLAVNNDLPIRTNSPVHSGKVRSVYWLTDADSRRLIQTKGYNVPEDTPLAIMVISDRISAFDCIFHGEGGLKGIPGKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQKARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLEKDQKLPDLLITPSTKGILTGIPGVPAQDDVNISRADIEANYQAFGFEKVEDIDLYEKLLKDGFKVISKALADLDQVFVDTKFEFGYVTDKNGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDPDILLNKDRMPEREALARDNALPLEAMMNVSRTYTGIAEKVTGAAIPLPANPKADIIKILREEYDLIV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: INSEC_ECO11
Sequence: MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYESQLYNWRSKQQNQQTSSERELEMSTEIARLKRQLAERDEELAILQKAATYFAKRLK
What is the function of this protein?
Involved in the transposition of the insertion sequence IS3.
What are the official names of this protein?
Transposase InsE for insertion sequence IS3.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: LINA2_SPHIB
Sequence: MSDLDRLASRAAIQDLYSDKLIAVDKRQEGRLASIWWDDAEWTIEGIGTYKGPEGALDLANNVLWPMFHECIHYGTNLRLEFVSADKVNGIGDVLLLGNLVEGNQSILIAAVFTDEYERRDGVWKFSKRNACTNYFTPLAGIHFAPPGIHFAPSGA
What is the function of this protein?
Catalyzes the conversion of the important environmental pollutant gamma-hexachlorocyclohexane (gamma-HCH or lindane) to 1,3,4,6-tetrachloro-1,4-cyclohexadiene (1,4-TCDN) via gamma-pentachlorocyclohexene (gamma-PCCH) (PubMed:12450824).  Proceeds by two successive 1,2-anti conformationally dependent dehydrochlorinations (By similarity).  Also shows activity with alpha- and delta-HCH, giving alpha- and delta-PCCH respectively, but not with the beta isomer (PubMed:12450824).
What are the official names of this protein?
Hexachlorocyclohexane dehydrochlorinase 2, HCH dehydrochlorinase 2.
What is the protein family that this protein belongs to?
Belongs to the HCH dehydrochlorinase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UVRC_PSE14
Sequence: MTQTFDPSAFLATCSGRPGVYRMFDAEATLLYVGKAKNLKKRLASYFRKTGHAPKTGALVSRIAQIETTITGNETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDGNYPRLSIHRGAKKAKGRYFGPYPSAGAIRESLSLLQKTFQVRQCEDSYFKNRTRPCLQYQIKRCKGPCVGLVEPEVYAEDVRHSVMFLEGRSNALSDELNATMEKAAMALDFERAAELRDQVALLRRVQDQQSMDGATGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVGEVMSAFLAQYFLGGIDRELPGEVIVNVINDDFPAFVDAVEELRGVEMVISHRVRGTRARWQQMAVTNAEQALTARLANRQHVASRFEALAKVLGLEDPPMRLECYDISHSSGEATVASCVVFGPEGPIKSDYRRFNIEGVTAGDDYAAMHQALTRRYSRIKAGEGKLPDVLLVDGGKGQMSMARDVLNELQVPDLILLGVAKGTTRKAGFETLYLNDAAHEFTLPGDSPALHLIQQIRDEAHRFAITGHRARRGKTRRTSTLEGVAGVGPTRRRDLLKHFGGLQELSRASIDEIAKAPGISKKLAESIYANLHSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_SHESA
Sequence: MSDYKFTLNLPETEFPMRGNLANREPEMLERWTKDGLYQQIRDSRIGRTPFILHDGPPYANGSIHIGHSVNKILKDIIVKSKTMSGFDAPYVPGWDCHGLPIELKVEQKVGKPGQKISAAEFREECRKYAAEQVDGQRADFIRLGVLGDWQKPYLTMDFATEANIVRSLSKVIENGHLHKGVKPVHWCTDCGSALAEAEVEYEDKTSPAIDVAFTATDSKALAAQFGVSDYSHPVAMVIWTTTPWTLPANRALSISPELDYSLVEFAKEGATHAVILADVLVEACMTRYGAESHSVLGKVKGVALELVRFKHPFLAFDVPAILGDHVTTDAGTGVVHTAPGHGQDDFVVGQKYGLEVANPVGDNGVYKPDTEFFAGQHVFKANDNVVALLKEKGALLHHVAYRHSYPHCWRHKTPIIFRATPQWFISMDNQNLRKQALSEIEQTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPITLFVHRETEELHPDSVSLMARVANRIEQEGIQAWWDLDAAELLGEEAEQYRKVTDTLDVWYDSGSTFASVVGARPEFHGHGVDLYLEGSDQHRGWFMSSLMISTAMTGKAPYKQVLTHGFTVDGKGRKMSKSIGNVIAPQQVTNKLGADILRLWVAATDYSGEMTVSDEILNRSADAYRRIRNTARFLLANLNGFDPAKDLVAVEDMVALDRWAVRRAAALQQEIIEAYEQYNFHIVTQKLMQFCSVELGSFYLDIIKDRQYTAKQEGHARRSCQSALFHIAEAMVRWIAPILSFTADEVWQLLPGQRDAYVFTQEWYQDLQSITLDTDLSDAYWENLLTVRNEVNKVIEQARRDKRIGGSLDAEVTLFADAALTEQLTHIGDELRFVLLTSEAKVLPLADATSDAVETELASLKLEVNATTAEKCERCWHHREEVGTIEAHPTLCHRCVTNIEGDGEVRLFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_RICCN
Sequence: MSITTERKQQLIKEYAITENDTGSSAVQCAILTERINNLTEHFKSNHKDHTSRRGLLILVGRRRRLLNYIKKNNVSKYLDLISKLGIRKIK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y1770_STAS1
Sequence: MILGLALIPSKAFQDEVNAYRKRYDAHYATIMPHITIKGQFKINDGDLESVKETIKSKIEGIPTIDIHATKASNFAPITNVIYFKVEKTETLERLFNQFNNGDFYGVADHTFVPHFTIAQGLTSQEFEDIYGQLKLAGIDYKETIEQLSLVYYDEKEEKWKVLENYNLA
What are the official names of this protein?
Putative phosphoesterase SSP1770.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: RL16_STRT1
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEVAREAFRLASHKLPVKSKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ARGI2_MOUSE
Sequence: MFLRSSASRLLHGQIPCVLTRSVHSVAIVGAPFSRGQKKLGVEYGPAAIREAGLLKRLSRLGCHLKDFGDLSFTNVPQDDPYNNLVVYPRSVGLANQELAEVVSRAVSGGYSCVTMGGDHSLAIGTIIGHARHRPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIKELQDKVPQLPGFSWIKPCLSPPNIVYIGLRDVEPPEHFILKNYDIQYFSMREIDRLGIQKVMEQTFDRLIGKRQRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGVYITEEIHNTGLLSALDLVEVNPHLATSEEEAKATARLAVDVIASSFGQTREGGHIVYDHLPTPSSPHESENEECVRI
What is the function of this protein?
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis.  Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS).  Arginine metabolism is a critical regulator of innate and adaptive immune responses.  Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells (PubMed:27745970, PubMed:25009204).  May suppress inflammation-related signaling in asthmatic airway epithelium (PubMed:27214549).  May contribute to the immune evasion of H. pylori by restricting M1 macrophage activation and polyamine metabolism (PubMed:27074721).  May play a role in promoting prenatal immune suppression (By similarity).  Regulates RPS6KB1 signaling, which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction (PubMed:22928666).  Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling (PubMed:25484082).  Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity (By similarity).
What are the official names of this protein?
Arginase-2, mitochondrial, Arginase II, Kidney-type arginase, Non-hepatic arginase, Type II arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y2134_SULIA
Sequence: MKRLPAVAGSFYESDPKKLKMQIEWSFRHNIGPRDIPKQTYEKKKRDNLFFVVPHAGYIYSGPVAAHSYYYLVSEGRPDVVIILGPNHTGLGSYVSAWPKGEWETPLGSVKIDEEILMQLVKESEVIDLDEKSHLYEHSIEVQLPFLQYFFDDDFKIVPIVIMMQTPEIAEFLADAIYNVMQKNPDKDIVVLASSDMNHYDPHEITVKKDEEAIEKIQQLDYKGLYEVVEGKDVTLCGYGPIMVNLILAKKFGKKAYILKHATSGDTSGPKDSVVGYLAARFGS
What are the official names of this protein?
MEMO1 family protein M1627_2134.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: EX7L_JANMA
Sequence: MISDRSPSPPSSAPAVLSVSALNQAVSRMLERNFPLSWVSGEISNFTCAASGHWYFTLKDSAAQVRAVMFRGRAQYADFMPREGDKVEVRALVTLYAPRGDYQLSVEAIRRAGVGNLYEAFLQLKEKLNAEGLFDPARKRAIPSFARTIGIVTSPQAAALRDILTTLQRRAPHVRVILYPTPVQGEGSANKIAQAIATASARAECDVLLVCRGGGSIEDLWSFNHELVARTIVGCDIPVIVGVGHETDFTIADFAADLRAPTPTAAAELAATPRADWLARLEAQADDMRYVLKRQLSDTAQTLDWLSRRLISPAAYIAHERMKLQNLQARLGHATRIPLSKAQFALAQLRNRWLSQLPDTQAQRLHVINHARRMSNQINNHIASQRQSLAALSAQLEMLNPQRTLERGYAMITDEKGKIVRAPKELQPRQSVTVRLADGTAQVGIASVQETLE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFH_ECOL5
Sequence: MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLTKNKVGIYSRPAKLSDIVHDGDRVEIYRPLIADPKELRRQRAEKSANK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: CAMP_HUMAN
Sequence: MKTQRDGHSLGRWSLVLLLLGLVMPLAIIAQVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKRFALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
What is the function of this protein?
Inhibits the growth of E. coli and B. megaterium and exhibits hemolytic activity against human red blood cells.
What are the official names of this protein?
Cathelicidin antimicrobial peptide, 18 kDa cationic antimicrobial protein, CAP-18, hCAP-18.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CH10_MYCPN
Sequence: MKITPIHDNILVSLVESNKEEVSQKGIITALANPDKNESAHKGTVVALGAGPAYGKSEKPKYAFGIGDTIYFKEYSGISFEEEGTKYKIISLEDVLAFEKHGNTKTTTVKKGAKKK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM14_PICST
Sequence: MSWYSVDSEIESLERRHAGHHHTVNIKYGYVILALSIVHMVLSISGKKLYFKNWAETGRASSWWRSVVSIPFWVSTLVWLAIFAFLSIFHIEELSENYTTAVKRLGRMAYCLVPFTIFISLRPPNTVGYQSGYYLEKLNLHKWISRLIFATAIGHGLGFLYKWTKEGALAEKIFKFDNFLGVTVFALMPVLIFASVNVMRRRNYRLFYILHNVTLWMFVVLIAFHARPGVPLLAVINLALLGYQIYQRFFKSYYLHDISVVESPYSKMQIIRIPRPETFPSYLPGSHIRLGYSATNISAWLYATHPFTIASTNDDSESTLDLVMNKPVNFPIDITSPYTMTGPFPSLPPQFYTTARHVNIICGGSGISFGLPIYKYFVNSNRSIPIRLIWCIRSSDDTFILDHLLPERSIDVQIYITSNTGSLNQQQSASTIFDEEADALLEGDSTTNIEMANLATDKEEKKTDHFNTIHDGRPNFDDAFGNLAAAVDVDEKWLIACGPRKLIDDCRKWTKGKDIEFYSELYEM
What is the function of this protein?
Probable cell surface metalloreductase.  May be involved in iron or copper homeostasis (By similarity).
What are the official names of this protein?
Probable metalloreductase AIM14.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family. AIM14 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYA_BRUSI
Sequence: MAGVNEIRSTFLDYFRKNGHEVVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGLEHRSYNRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEDAISFAWNLITREFGLPKDKLLVTVYHTDDDAANFWKKIAGLSDDRIIRIPTSDNFWAMGDTGPCGPCSEIFYDHGDHIWGGPPGSPEEDGDRFIEIWNLVFMQFEQQTPELRIDLPRPSIDTGMGLERIAAVLQGVHDNYDIDLFKALIRASEEATGVKAEGDFRASHRVIADHLRASSFLIADGVLPSNEGRGYVLRRIMRRAMRHAQLLGAKEPLMWRLLPALIREMGQAYPELIRAESLISETLKLEETRFRKTLERGLGLLSDASENLAEGDRLDGETAFKLYDTYGFPLDLTQDALRQRGIAVDTEGFNVAMERQKAEARANWTGSGEAATETIWFGIKDKVGATEFLGYETESAEGVIASLVRDGVEVPSVREGETISVVVNQTPFYGESGGQQGDTGTISGEGFVIAVKDTQKKGEGVFVHIGEVTEGTAKAGDVVELKVDSARRTRIRSNHSATHLLHEALRETLGTHVAQKGSLVAPDRLRFDFSHPKPISAEELEAVENLANEIILQNAPVTTRLMAVDDAIAEGAMALFGEKYGDEVRVVSMGTAKHGSKAGKAYSVELCGGTHVRQTGDIGLVRIISEGGVAAGVRRLEALTGEAARLYLEEQDERVKAIASALKTTSADVLDRVNALIDERKKLERELADARKKLALGGGSSDGGSAVEAVNGVNFLGKIVTGVSPRDLKPLADEGKKQVGSGVVLFIGVGEDGKASAVAAVTEDMVGRFSAVDLVRAASAALGGAGGGGRPDMAQAGGPDGAKAADAIAAVKALIA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGF18_HUMAN
Sequence: MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQPELQKPFKYTTVTKRSRRIRPTHPA
What is the function of this protein?
Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration.  Required for normal ossification and bone development.  Stimulates hepatic and intestinal proliferation.
What are the official names of this protein?
Fibroblast growth factor 18, FGF-18, zFGF5.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.