PharMolix/UniProtQA huggingface dataset:
Protein: PPID_MOUSE
Sequence: MSHASPAAKPSNSKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGTGSTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGEKPAKLCVIAECGELKEGDDWGIFPKDGSGDSHPDFPEDADIDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYAKVLRYVDSSKAVIEKADRSRLQPIALSCVLNIGACKLKMSNWQGAIDSCLEALEMDPSNTKALYRKAQGWQGLKEYDQALADLKKAQEIAPGDKAIQAELLKVKQMIKAQKDKEKAVYAKMFA
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.  Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes.  Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control.  May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes.  May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus.  May regulate MYB by inhibiting its DNA-binding activity.  Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity region.  Involved in regulation of UV radiation-induced apoptosis.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase D, PPIase D, 40 kDa peptidyl-prolyl cis-trans isomerase, Cyclophilin-40, CYP-40, Rotamase D.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: SRP19_PYRAB
Sequence: MSKFVIWTSELDSRLSKKYGRVVPRNLAVERPSIEEIEEAAKSLGFKVLQVEREKLNPKLSGIDEDLRTYGRIIIESPYGKAKTLKIIAQKIRELRRRR
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_NITWN
Sequence: MATITAAMVKELREITGVGMMDCKQALTENNGDMQAAIDWLRKKGLSKAAKKAGRVAAEGLIGVVTSGNKGVVVEVNSETDFVARNEQFQGLVKMVAQVALSVGADVEVIKAAEVGNATVATTISDAIATIGENMTLRRANSLEVPKGIVAGYVHNAVIDGAGKLGVIVALESAGNADELAALGRQVAMHIASANPVAVDPSGVDPEVVKREKDVLADKFRQQGKPEAMIEKITESGLKTFFKEQTLLEQPFIFDDKRSVGQALKEAEGRVGAPVRIAGFVRYALGEGIEKAESDFAAEVAAAAGQG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F162B_HUMAN
Sequence: MLRAVGSLLRLGRGLTVRCGPGAPLEATRRPAPALPPRGLPCYSSGGAPSNSGPQGHGEIHRVPTQRRPSQFDKKILLWTGRFKSMEEIPPRIPPEMIDTARNKARVKACYIMIGLTIIACFAVIVSAKRAVERHESLTSWNLAKKAKWREEAALAAQAKAK
What are the official names of this protein?
Protein FAM162B.
What is the protein family that this protein belongs to?
Belongs to the UPF0389 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PP4R2_CHICK
Sequence: MDVERLQEALKDFEKRGKKEVCPILDQFLCHVAKTGETMVQWSQFKGYFIFKLEKVMDDFRTSAPEPRGPPNPNVEYIPFEEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTGTDKFLRGVEKNVMVVSCVYPSSEKNNSSSLNRMNGVMFPGNSPGYSERSNVNGPGTPRPVNRPKVSLSTPMTTNGLPDSTEHKESSLQQTEDKKHSDSPASDSEGAQSSPVKNKHSEDDPAEAEGHEVKRLKFDKEGEARDAPNQSASSEVSLGMGEESETSSTSQDKEKDSICARQHCTEEDEEESFMSPRNAGPDRKDQEKDTESSTVNEESSEENQMEESDQSQAEKDLHSDNSESSGSVSSGADCSETEELGSYGSETPETSSETPMENSEEATEVADEPMEQD
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 2.
What is the protein family that this protein belongs to?
Belongs to the PPP4R2 family.
Protein: ACPB_BACAN
Sequence: MEKDIKRQIQILEIITSEEKWFTTIEISKILRCCNKTIMKDISFIKDFLPEDWHIKIKKGKGVRIYLPYNKHRNEITFLLFRESLTFRILQHLFERETKTIATLAERLYIQVPSILPALKRVENYLKKFGLKLRKKPLRLEGDEVRIMIMYLDLYLKSYNDTEWPFEKLKKEVIFQYLGTLEESLGISLHVVSKRHLSFFIAILLKRKQQGYKVQLNRKFLYFNTETPDYVKIGRIFEKLEREFGVSLTVQDKILLTISIKSSKYVYKDINKEKEESVQYFKEGNLSIYELVKDFINSLEEKLKVDLISDEEFIFALVDYFKRTIYHLQYLCMFERPQKQTIQYMQTEHSETFSAVKEVYTEFVKKNEIADYVSVEEIAKVTMYIEASRLRYTSNYKKVLLVTGESESWAEYLAATLAKRFGDKIQISTVFFAKKSDHDVNADFIISTIPLDLGSTPIICINSIPTERDYTNIQYYLDLQDG
What is the function of this protein?
AcpB and AcpA regulate cap gene expression and capsule synthesis.
What are the official names of this protein?
Capsule synthesis positive regulator AcpB.
What is the protein family that this protein belongs to?
Belongs to the AtxA/AcpA family.
Protein: RS12_THET2
Sequence: MPTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAAKTAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: OTOP2_MOUSE
Sequence: MSEELVPHPNESLPGPRASPREVWKKGGRLLSVLLAVNVLLLACTLISGGAFNKVAVYDTDVFALLTTMMLLAALWIVFYLLRTARCPDAVPYRDAHAGPIWLRGGLVLFGICTLVMDVFKTGYYSSFFECQSAIKILHPIIQAVFVIVQTYFLWISAKDCIHTHLDLTRCGLMFTLATNLAIWMAAVVDESVHQAHSYSGSHGNTSHTRLNPDSKRAGGAAEEDPCLCSTAICQIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRLLASTHGHGHTPSRVSLFRETFFAGPVLGLLLFVVGLAVFILYEVQVSGERGHTRQALVIYYSFNIVCLGLMTLVSLSGSVIYRFDRRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVVGSPRDLQGALNLSHALLMIAQHTFQNVFIIESLHRGPPGAEPREMPPKEPCQGITFANLDAIRTLPSCPPTPRLVIPNLESPQEAVAIISAPRCHWRRRCLKDISLFLLLCNVILWIMPAFGARPHFSNTVEVDFYGYSLWAAIVNICLPFGIFYRMHAVSSLLEVYVLS
What is the function of this protein?
Proton-selective channel that specifically transports protons into cells.  Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.
What are the official names of this protein?
Proton channel OTOP2, Otopetrin-2.
What is the protein family that this protein belongs to?
Belongs to the otopetrin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YR503_MIMIV
Sequence: MNYNKENILTMSDKIDFSLIKFQDSKFKQTCLKYISNNGKKLSFRSERIPSESILICGMNYGLMIYVDDVMRSCLEHMDNYFSSDEVKKSMFGPKYDKMTYVPTIRKGKMGDYIILHFQKSQEEIDSVICKNGFKQDIKLTGKYTSSGKNEYKIHDSSNNSETSLKDYLSQSKDIQIVFHYKSISKRPNTNSYGVKLSITKMELDNPIKTNRYNKIYYNLDVTKSKSLSIKI
What are the official names of this protein?
Uncharacterized protein R503.
Protein: SSRP_RALSO
Sequence: MTIADNKKAFFDYFVEERYEAGIALEGWEVKAIRAGRVQIKEGYVVIRDAELFLIGAHISPLQSASTHVKPDPTRTRKLLLHAEEIKKLIGKVEQRGYTLVPLNLHYARGRVKCEIGLAKGKKLYDKRETEKDRDWQREKARLMREKA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SSB_BPS14
Sequence: MFKRKSTAELAAQMAKLAGNKGGFSSEDKGEWKLKLDNAGNGQAVIRFLPSKNDEQAPFAILVNHGFKKNGKWYIENCSSTHGDYDSCPVCQYISKNDLYNTDNKEYGLVKRK
What is the function of this protein?
Single-stranded DNA-binding protein that participates in viral DNA replication, recombination, and repair.  Coats the lagging-strand ssDNA as the replication fork advances.  Stimulates the activities of viral DNA polymerase and DnaB-like SF4 replicative helicase, probably via its interaction with the helicase assembly factor.  Together with DnaB-like SF4 replicative helicase and the helicase assembly factor, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions and mediates homologous DNA strand exchange.  Promotes also the formation of joint molecules.  mRNA specific autogenous translational repressor.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB protein, Gp32, Helix-destabilizing protein.
What is the protein family that this protein belongs to?
Belongs to the Tequatrovirus single-stranded DNA-binding protein family.
Protein: RBM45_RAT
Sequence: MDDAGSSGGSGGFRPGVDSLDEPPNSRIFLVISKYTSESVLREHFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSVIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVLESPEQDYYSSVRQETLGHEPRGNLFPFVGEQQSEFSTFDKNDSRGQEAISKRLSVASRVPFTEEQLFSIFDIVPGLEYCEVHRDPYLNYGHGVVQYFNVASAVYAQYKLHGFQYPPGNRIAVSFLDDGSNSADLIRKMATQMVAAQLASTVWSNPSHQQFLQFGGSAGSQVPQIQTDVVLPSCRKKAPPETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRMSANDAITTLHGKILNGVRLKVMLADSPREVSKKRQRTY
What is the function of this protein?
RNA-binding protein with binding specificity for poly(C).  May play an important role in neural development.
What are the official names of this protein?
RNA-binding protein 45, Developmentally-regulated RNA-binding protein 1, RNA-binding motif protein 45.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. May shuttle between cytoplasm and nucleus.
Protein: UBID_PSEMY
Sequence: MQYRDLRDFIRELEKRGELKRIQTPVSPILEMTEICDRTLRKGGPALLFEKPTGFDVPVLGNLFGTPKRVALGMGAEDVAELREIGKLLAFLKEPEPPKGLKDAWSKLPIFKKVISMAPKVVKDAPCHEVIEEGEDVDLNRLPIQHCWPGDVAPLITWGLTITKGPNKERQNLGIYRQQVIGRNKVIMRWLSHRGGALDYREWCQKYPDKPYPVCVALGADPATILGAVTPVPDTLSEYAFAGLLRGHRTELIKAVGSDLQVPASAEIVLEGVIHPGETAPEGPYGDHTGYYNEVDTFPVFTVERITRRREPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEITDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDINARDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPISGLGSKMGLDATHKWPGETSREWGRAIEKDPAVVARVDALWGELGID
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RHGBA_MOUSE
Sequence: MWDQRLVRLALLQQLRAVYGIKVKGGRGQCDRRRHETAATEIKGKVFGVPFNSLPHSVVPEFGHIPSFLVDACASLKEHIHTEGLFRKSGSVVRLKALKSKLDQGEACLSSALPCDVAGLLKQFFRELPEPVLPADLHEALFKAQQLGAEERNKATLLLSCLMANPTVDILRYFFNFLKSVSLRASENKMDSSNLAVIFAPNLLQTSEGHEKMSANTEKKLRLQAAVVQTFIDCASDIGRVPDFILEKIPAMLGIDGLCTTPSLEGFEGDFETPGECKRKRRQSVGDFVNGALNKLKSSRTPSITPQQDRTAQASASPLILTPSVKRKLPGESSHAFSSKKRKSIKHNLNFELLPSHFFSSNSTPVSVHLDTSPDGSSQTSLSPIAMSGNHLVSTELRRSKRIASKKVYRVESGKAGCFSPKVSRKEKTRRSLRLKFSLGKNRDSDGCSVINRYENVGRRLANQQNLKSRIDSVKTGLLFSPDIDERLLKKGSEKISKSEEHLLTPDQLDGTGYRMSWTEPSNSSFQDMSANGTSPIMQNLEVKSFSLEPDITVEKSPVVSCELRPSTFHSQPDSSVLSLSGDEGNLASETLQKIQKAFSESGSDLHMVINHEQSSVTNTGEEVEFRDVTVTESKGHDGSCAGEEENCPSERNFSPDQSPEFAREADEECYSTQMKVECEGLHSETPKADPLILQAFPGEEPAEEPQSPRNQLSTPSRGNENGGESAGASGAPGEDESTCSVAVLSKPRPQRLSRQQSLVEKCDSVAPGALQVTEHGKVSDHIQWFNKLSLNEPNRGKVKSPLKFQRTPVRQSVRRINSLLEYGRQPVRQKLAIFGDAASPLVKSVSCDSALPSCVQNTSKGPTAPLITSGLEAQKSTSCNKSSVELTSKSFTKMKRHPDPLSASLGTPRLCKQENKSNGHIKFPLDDLTNHERLKFVVNNNVAFSPGMKNRVVRKPSEKERVWYKGSPKNPIGKTQLLPTSKPVDL
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 11A, Rho-type GTPase-activating protein 11A.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS15_ACIBT
Sequence: MALTNADRAEIIAKFARAENDTGSPEVQVALLTAQINDLQGHFKAHKHDHHSRRGLIRMVNQRRKLLDYLNGKDHERYTALIGALGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YVYF_BACSU
Sequence: MGELANCPKCNALFLKTKLQTVCQACIKEEEKSFETVYKFLRKQENRQSTLSRITEETGVEEELILKFIRQKRIQITHLPNLAYPCERCGTSIREGKFCKACQSDIKDQMDHLNHEDALKIEKENSKKDTYYAYNTKNS
What is the function of this protein?
May be involved in the assembly, structure, or function of the flagellum.  May polymerize to form a filamentous structure that is part of the flagellum.
What are the official names of this protein?
Uncharacterized protein YvyF.
What is the protein family that this protein belongs to?
To S.typhimurium FliF.
Protein: VPB36_MYCTU
Sequence: MALNIKDPEVDRLAAELADRLHTSKTAAIRHALSAQLAFLESRAGDREAQLLDILRTEIWPLLADRSPITKLEREQILGYDPATGV
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC36.
What are the official names of this protein?
Putative antitoxin VapB36.
Protein: SPRE_XENTR
Sequence: MAATGALGSVLCVLTGASRGFGRTLAHLLCPRLLPGSTLLLVSRTEEALKGLAGELAHKYPGVRVRWEAADLGTSEGVSAAVRAAGELQVGAAQKLLIINNAGSIGDVSKMFVDFSDPKEVTDYMMFNVSSPLCLTASLLKTFPRRPDLQRVVVNVSSLAALQPFKSWALYCSGKAARDMIFRVLAEEEKDVRVLNYAPGPLDTDMHVVARTQTADPELRRFLMDRKEKGKMVDIQVSAKKMLDLLEADAYKSGDHIDFFD
What is the function of this protein?
Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
What are the official names of this protein?
Sepiapterin reductase, SPR.
What is the protein family that this protein belongs to?
Belongs to the sepiapterin reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_PSEPW
Sequence: MKVRASVKKLCRNCKIIRREGVVRVICSAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PER24_ARATH
Sequence: MANKSLEIRFLFPLVLFLVVKLLCVDGKGFNNNGHKIRKGRWEGKLKMNFYHNSCPGAEDIVRQIVWKKVEANRSLAPKLLRVHYHDCFVRGCDASLLLDSVAGKAVSEKEARPNLSLSGFEIIDEIKYILEKRCPNTVSCADILTLAARDAVSYEFERPLWNVFTGRVDGRVSLATEAARDLPSAGANFTTLQKLFAESDLDVVDLVALSGAHTIGIAHCGVFGRRLLNFTGKGDTDPSLNPSYASFLKSECSDKSLRLNPSAVVGMDPTGPLAFDSGYFVSLLKNKGLFTSDAALLTDPSAAHIASVFQNSGAFLAQFGRSMIKMSSIKVLTLGDQGGEIRKNCRLVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 24, Atperox P24, ATP47.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YFEO_ECO5E
Sequence: MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQRLPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPGLIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALFGTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQMEMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVLVLGIGGFILGILGVIGGPVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVALGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVMLPAWLLLAGKPMMMVNRPKQQPPHDNV
What are the official names of this protein?
Putative ion-transport protein YfeO.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOE_BUCBP
Sequence: MLTVEVYEMSKKIDIKFKLTIQEKIEIFNIIKNYRTVRSSLIEILKFVQKSYGWISNELITELACILKISKCDIEEIATFYSQIFRQPIGRNIIKYCDSVVCYVNGCEKIRCSLEKNLNVNVGETTKDFKFTLLPICCLGNCDKSPTIMINDDLYSNVTEYSVIVLLESYQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit E, NADH dehydrogenase I subunit E, NDH-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
Protein: MSCL_BRUA2
Sequence: MLKEFQEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLAGDPKTTLAAAREAGATIAYGNFITLLINFLIIAWVLFLVVKLMNRLKKREEAKPAPAAPSEEVLLTEIRDILAKQQKA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FETP_KORVE
Sequence: MAHMVKCVKLGREAEGLEEPPFDSELGQKIYNNVSAEAWRGWTEHQKMLLNEYRLQPWKKEHQEFLVQQMEAYFFGEGSEAPKEFVPPSH
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: TLR5_HUMAN
Sequence: MGDHLDLLLGVVLMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQVLNTTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEHELEPLQGKTLSFFSLAANSLYSRVSVDWGKCMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHNDLPANLEILDISRNQLLAPNPDVFVSLSVLDITHNKFICECELSTFINWLNHTNVTIAGPPADIYCVYPDSFSGVSLFSLSTEGCDEEEVLKSLKFSLFIVCTVTLTLFLMTILTVTKFRGFCFICYKTAQRLVFKDHPQGTEPDMYKYDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENRIANIQDAIWNSRKIVCLVSRHFLRDGWCLEAFSYAQGRCLSDLNSALIMVVVGSLSQYQLMKHQSIRGFVQKQQYLRWPEDFQDVGWFLHKLSQQILKKEKEKKKDNNIPLQTVATIS
What is the function of this protein?
Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed:11323673, PubMed:18490781).  Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota (PubMed:29934223).  Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response (PubMed:20855887, PubMed:11489966).  Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life (By similarity).
What are the official names of this protein?
Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ACCO_DENCR
Sequence: MELLEGSRRSDAMAVLRDACENWGFFELLNHGISHEPNEQSETVNKEHYREHYRRFREQRFKEFAAKTLDSGENVDGDNLDWESTFFLRHLPTSNISQVPDLDEDCGSTMKEFALGLEKLAERLLDLLCENLGLEKGYLKRVFCGGSDGLPTFGTKVSNYPPCPKPELIKGLRAHTDAGGIILLFQDDTVSGLQLLKDEEWIDVPPMRHSIVVNIGDQLEVITNGKYKSVMHRVVAQTNGNRMSIASFYNPGSDAVIFPAPELVEKEAAEKKKETYPKFVFEDYMKLYVRQKFEAKEPRFEAMKTMDAVISSQPIPTA
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase, ACC oxidase, Ethylene-forming enzyme, EFE.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PTH1R_PIG
Sequence: MGAARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPADIMESDKGWASAPTSGKPRKEKASGKLYPESGEDTGSRHQGRPCLPEWDHILCWPLGAPGEVVAMPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPLPPVAATSYVGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAIFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRTGLGLPLSPRLLPAATTNGHPQLPCHTKPETPALQTTPPVVAAPKDDGFLNGSCSGLDEEASAPERPSVLLQEEWETVM
What is the function of this protein?
Receptor for parathyroid hormone and for parathyroid hormone-related peptide.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
Protein: SAP10_ARATH
Sequence: MVNETEALPCEGGCGLYGTRVNNNLCSLCYKKSVLQHSPALRFEPETEQSQCCPPTNSPAVEEEPVKKRRCGICKRKVGMLGFKCRCGHMFCGSHRYPEEHSCPFDYKQSGRLALATQLPLIRADKLQRF
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 10, AtSAP10.