PharMolix/UniProtQA huggingface dataset:
Protein: SYP_METBU
Sequence: MAEQEKEATLPSKENFSEWYNGMLQIAEIMDVRYPVKGSYVWYPFGFSIRRNVYDIIRGLLDKDHQETLFPLLIPENEFMKEAEHIKGFEEEVYWVLNGGTTPLDVKLALRPTSETAIYPMYRLWVRSHADLPLKLYQIVNTFRYETKHTRPLIRLREITSFKEAHTVHATWDEAASQVEEAIRLYIEFYKRLAIPVLPSKRPSWDKFPGADYTIAVDSLMPDGKTLQVGTAHHLGDNFAKTFDIKYEDVDGEQVYAHQTCYGVSERCIATLLSTHGDDKGLVLPPEVAPTQVVIIPIIFKEPEAVLNACNDVKAELEAAGVRVTIDDSDKRPGSKYYKWEMKGVPLRIEIGPRDLKNEAAMLARRDTGEKEQVPLASIKDEVLSRFKIIQTSLLEKATSELNERIFDCSTVDDVKEKVQDGIALVPWCGEEKCGLDLDEQVGAGILGIPTDMDEDGTYKCPICSKETRTRVYVARTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_ECOLU
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIDGQSKPLLIYGKPEAQQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PANC_SALA4
Sequence: MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPQGLEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIRKMVADMSYDIEIVGVPIIRAKDGLALSSRNGYLTAEQRKIAPGLHNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRADDIQIRDADTLQELTETSKRAVILAAAWLGQARLIDNQSVTLAQ
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_KLEP3
Sequence: MRRVRYFLLALLVAILAALAGGYYWLHSGNPDALRKIVLQQCVPHQQQQQNPSPCAEVNLKGGYVLFKDRNGPLQYLLMPTYRINGTESPLLLDPLTPNFFWQAWQGREIMSQRHGAPVPDNAISLAINSRSGRTQNHFHIHISCLRPDVRAQLDKDAAAVSSRWLPLPGGLQGHEYLARRVTEAELAQRSPFLMLAEEVPEAREHMGRFALAMAQQSDGSLVLLATERNLLTLNRASAEEIQDHRCAILNANH
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYT_CHIGU
Sequence: MKAIYLILTVLCGFSASTKTGGWRDKDVDDEDIRKFATLAASENSKMSNSLYFEKLVKVIEAKSQVVSGVKYNITFEIAPTECKKNGKGYDKLSECPLLESAPHQTCTAIIWTRSWLNDTQILKLKCKEGGSSC
What is the function of this protein?
Inhibits various C1 cysteine proteases.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as a housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Cystatin-1, Cystatin JZTX-75.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MYT1L_HUMAN
Sequence: MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKSSDSHVKKPYYGKDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV
What is the function of this protein?
Transcription factor that plays a key role in neuronal differentiation by specifically repressing expression of non-neuronal genes during neuron differentiation.  In contrast to other transcription repressors that inhibit specific lineages, mediates repression of multiple differentiation programs.  Also represses expression of negative regulators of neurogenesis, such as members of the Notch signaling pathway, including HES1.  The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro.  Directly binds the 5'-AAGTT-3' core motif present on the promoter of target genes and represses transcription by recruiting a multiprotein complex containing SIN3B.  The 5'-AAGTT-3' core motif is absent from the promoter of neural genes.
What are the official names of this protein?
Myelin transcription factor 1-like protein, MyT1-L, MyT1L.
What is the protein family that this protein belongs to?
Belongs to the MYT1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially binds to DNA binding sites that are in an open chromatin configuration.
Protein: PDXA_RALSO
Sequence: MLNIAITTGEPAGIGPDITVTALLRLLRQPAPRHADVRWHVIGDAALLQARADAIGLGDAWRDAAAALTVVARPLGAPVRTGVLDAANGRYVLDLLDAAIDGCLPDAAGMARYDAMVTAPVQKSTINDAGVPFTGHTEYLAERSRTPRVVMMLAGPQPAHGNAMLRVALATTHLPLREVPDAITPAVLDETLDIVQRDLRARFGMAAPRILVTGLNPHAGEAGHLGREEIEVIEPAVVRARARGIDARGPYPADTLFQPRLLADADCVLAMYHDQGLAPLKYGTFGHGVNITLGLPFVRTSVDHGTALDLAGTGRAEAGSLLEAIDTAVEMARHAAHS
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI3G1_DROAN
Sequence: MPGIETIKSSWADEVELDYGGLPPTTETVENGHKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTVAKRRTWTKFGESKNDKPGPNSQTTMVSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPYKGTAMDTNMMEKKATAAAAAAVDAPKSGKYVPPFLKDSVGKVGMGMRGRDDTAAIRISNLSESMTEADLEELVKKIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWSKPQNN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G-1, Eukaryotic translation initiation factor 3 RNA-binding subunit-1, eIF-3 RNA-binding subunit 1, Eukaryotic translation initiation factor 3 subunit 4-1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_THEVB
Sequence: MPILAQAVLASHNAGKVKEFQGWLQPWIGELVALPAAIEIAETADSFVANACLKAATAAKVMGEWAIADDSGLAVHALQGAPGIYSARYGATDAERIERLLREMADVSDRAAEFICVIALARPDGTIAVTTEGRCAGEILTAPRGQGGFGYDPVFWVPSQQRTFAEMSPVEKQQVSHRGQALQRLREYFQTLNP
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SNMP2_AEDAE
Sequence: MMVMNTELRQDTPQFKRWEAVPQPLDFKVYIFNVTNPYEVQMGRRPRVVEVGPYVYFQYRHKDNIRFSRDRSKVHFSQQQMYVFDAESSYPLTENDQLTVLNMHMNSILQIIDTQAKETITNFRSDVNNTLEKIPVVRVIKRIIEKTTPIQSILQLAEDETYDSLRLINAELNRIFGRPDSMFLRTTPREFLFEGVPFCVNVIGIAKAICKEIEKRNTKTIRVQPDGSMKFSFFNHKNMTNDGTYTINTGIKEPALTQMIEYWNGRNTLDRWINQSAGSSSKCNKIVGTDGSGYPPFREGVERMTIFSSDICRTVDIKYVGPSSYEGIPALRFETDSHFLNEIGPEYGNDCYCVNRIPKAIVKNNGCLYKGALDLSTCFDAPVVLTHPHMMGAAQEYTSLIDGLYPDPEKHQIFVDVEPLTGTPLNGGKRVQFNMFLRRIDSIRLTDRLQTTLFPVLWIEEGIALNEDMVKLIDDSLMKVLTLLDIVQWVMIGSGLLLAIIMPIVYFIKRRPSSGSITPTLTTTTSTVSISDGGGLGGNPQK
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 2, SNMP2Aaeg.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DHH1_ASPOR
Sequence: MAEALASQLNNTTLGEASSDTRWKDQLKAPAKDARPQTEDVTATKGLEFEDFYIKRELMMGIFEAGFEKPSPIQEETIPVALTGRDILARAKNGTGKTAAFVIPTLERINPKSTKTQALILVPTRELALQTSHVCKTLGKHLGINVMVTTGGTGLMDDIIRLNDAVHILVGTPGRVLDLASKGVADLSECPTFVMDEADKLLSPEFTPVIEQLLSFHPKDRQVMLFSATFPLIVKSFKDKHMRNPYEINLMDELTLRGITQYYAFVEEKQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGYSCFYSHARMLQQHRNRVFHDFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRFGHLGLAINLINWDDRFNLYKIEQELGTEIQPIPQNIDKKLYVYESPETIPRPIANASQAQLATSGNQTQNMGERRHNNHSNGGHYQFGRGRGSYRGGRSQGQRRNMQNEMNKFGTSQNQQQSGKSQPAQVSPN
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1.  Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs.  May also have a role in translation and mRNA nuclear export (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dhh1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: KITH_PYRAE
Sequence: MLVVIVGPMFAGKTTELIRRVERYVIAGRRAIVFKPSLDVRYDASKVAAHNGLKFDAFVIPPDKDGVEIIRKMGAEYDVVAVDEIQFFPVDLADALNQLANGRIVIAAGLNLDFRGEPFETTARAMAFADRVISLSAVCKLCGKPATRTQRLINGVPAPRHSPRILIGGNESYEARCRRHYVIPP
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTSA_STRP3
Sequence: MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK
What is the function of this protein?
Part of an ATP-driven transport system.
What are the official names of this protein?
Metal ABC transporter substrate-binding lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SPE39_DANRE
Sequence: MTRAKPEDDEYWNSSKFKAFTFDDEDDEFSRLKESKRAVNSILVDDDDDEDDVEKVSWSGEPVGSISWSVRETASSIRSGSEQNFPKIDTAPSLSKQGSGYSLSSLFKAKSKPTAFQSFSESFSETSARTYAPELRKPKSDGKDFVSDLSPEETIRRMQKGRAFSMEKFRSLQDKLLLLDEAVSVYDGNVITAVLIYLKKSLSKEILFRELMPREVALRHYIHYLKEMGEQKLLVELLKALGRTEDMALMQYKEHLNIKDEGRRRDFLKSCLSLPFSQDDSTHVQDHYTLLERQIIIEASDKKADTDIFKKFPRKASILNMPIITTLYYSCFYHYGEPEGTFSSPSNIRKTFRISEKQYITTALGARAKLKSWFDVDSLFNTKNWLGYTKKRSPIAFHRVVDILQKNSAPVQVLQEYVNLIDDPELKLSVALKYKCHDIIINTYRDLKDRQQLIVYREKLERDSPEYRKIQELLNNGQIRWKN
What is the function of this protein?
Proposed to be involved in endosomal maturation implicating in part vps33b.  In epithelial cells, the vps33b:vipas39 complex may play a role in the apical rab11a-dependent recycling pathway and in the maintenance of the apical-basolateral polarity.  May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of vps33b.  May play a role in vesicular trafficking during spermatogenesis (By similarity).  May be involved in direct or indirect transcriptional regulation of E-cadherin.
What are the official names of this protein?
Spermatogenesis-defective protein 39 homolog, hSPE-39, VPS33B-interacting protein in apical-basolateral polarity regulator, VPS33B-interacting protein in polarity and apical restriction.
What is the protein family that this protein belongs to?
Belongs to the SPE39 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Early endosome. Recycling endosome. Late endosome.
Protein: PYRD_KINRD
Sequence: MVAGSGRTYRTVYRHLLTRVDPEVAHRWAFAGMRAASRVPVAPHVLRRAFVEPDPRLRTRVLGIDFPTPLGLAAGFDKNATGISALGNFGFSCVEIGTVTARPQPGNPKPRLHRLVADRAVVNRMGFNNAGAEVVARRLRQLRAVPPVHPVVIGVNIGKSKVVAEADAAQDYATSARLLAPYADYLVVNVSSPNTPGLRDLQAVEKLRPVLRAVREAADGAAHRHVPLLVKIAPDLSDEDVDAVADLAVEEELDGIVATNTTISREGLRSPAALVAAAGGGGLSGAPLKERSLEVLHRLAARTRGSLVLVSVGGIETAQDIAERLDAGASLVQAYTAFIYEGPGWARRVLGELAASRSRRETDRPS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YC048_YEAST
Sequence: MQIKNIVAVLATVTAINAQVGIEPNATTPNATQPNATQPNTTLPTASVTTTVSIGEAVVNTMAAGAFGAAIAAGVAFLF
What are the official names of this protein?
Uncharacterized protein YCL048W-A.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: UPP_MYCMS
Sequence: MAFTEIKHPLIIDKLTRMRKTETSSKDFRENLNEIAQLMVYEIFRDLKLEPVEITTPVAKTTGYTINQPVVLVPILRAGIGMLDGIQKLIPTARIAHVGLYRDETTLEIHQYFAKTTKDIDKSYVIVVDPMLATGGSACKAIDIVKQWGAKEVKFVCLVAVEPGIKRLQEQHPDVEIYAASKDEKLNEKGYIIPGLGDAGDRIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: TTL12_CAEBR
Sequence: MSPSSSDRLGYPFSTFLDQHSAQLNASAVPPELWHSLYRKLSDQTFDAGDHFQIICEMDENDEKKTLFVRALEDMHNNDEENIFLIDHFISFPAESARKCVESNEKLPERLAALFGIDDDDCSSDGDETVEKIETSCEKEEEEHARRLSEPGLPRHESVDARLSSYSVDDPKKTMTERVMRNLWKFAQTYTVSYQLENGEMEKKHVWYVMDDFGSRIRHSGCPNVRIVPLMFLPQNCAYSIMFLTKPVKIDDEITMDWAANVITAKNPEWRQYLEMPWAEKDFSSESMVPGPPTLEYFTSGRNPDFLADEKDKKTCESAIFSALSVLKKQGKIKIFLQIFADDTQLTEHLKSRQIEYVDDWKAADVIWMIKHFHDYSNLAQENPCAQINQFPFESCITVKDLLAACAMRDPSKNDWYQLTYNLNTQLPEFVARFQNRQKNGEHNVWIVKPWNLARGMEMAVTDDLNQIIRMVETGPKIVCEYIARPLLFPRPDNGNKVKFDLRYIVFVNAIGPVTAYVYNRFWIRFAINQFQLGAYDDLETHFTVFNYLDKEKVLQMKCEKFVEIIEKTYPKLKWTQIQADINSTIRKAIEVAASEPSPRGVAPNTQSRAMYGVDIMLQESPESPDVIKPTLLEINFMPDTTRACQYYPDFADTVFDTMFLDEIDPTKVTPI
What is the function of this protein?
Regulates microtubule dynamics in uterine muscle cells.
What are the official names of this protein?
Tubulin--tyrosine ligase-like protein 12, Inactive tubulin--tyrosine ligase-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
Protein: PDXJ_HELPY
Sequence: MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDRRHIQNEDVLKLLEISPLPINIECSINAEITDFLCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGIEVSLFIDPLKDALHFAREHQVKQVEFHTGVYANLHNALYSNANNQIHAISVLKDKSPKELKEELHNAFLQLRRMSKEAFFMGITACAGHGLNYTNVKELLKIPSLRELNIGHSVVSKAVLVGLEKAILEMAQLIKR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTHFS_MOUSE
Sequence: MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQDEVETEVIIKDIFKQGKICFIPRYQFQSNHMDMVRLTSSEEIALLPKTSWNIHQPGEGDVREEALSTGGLDLIFLPGLGFDKDGNRLGRGKGYYDTYLKRCVQHQEVKPYTMALAFKEQICPQIPVDEHDMKVDEVLYEDSPAS
What is the function of this protein?
Contributes to tetrahydrofolate metabolism.  Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.  Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10-methenyltetrahydrofolate (By similarity).
What are the official names of this protein?
5-formyltetrahydrofolate cyclo-ligase, 5,10-methenyl-tetrahydrofolate synthetase, MTHFS, Methenyl-THF synthetase.
What is the protein family that this protein belongs to?
Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA2_ORYSJ
Sequence: MPFSPPCLDPAAAAAASLSFLPAAAARPPAPCAVAPRSRRALRVAASVATAPESAAAQGRLESLSQVAGVLGTQWGDEGKGKLVDILAQRFDIVARCQGGANAGHTIYNSEGKKFSLHLVPSGILNEKTMCVVGNGAVVHLPGFFKEIDGLESNGISCEGRILVSDRAHLLFDFHQTVDGLREVELGNSLIGTTKRGIGPCYSNKVIRNGLRVSDLRHMDTFGAKLNTLLRDAALRFEGFEYSTKTLKEEVEKYEKFAERLGPYITDTVHFMNQSILQNKKILVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRSIGDLIGVVKAYTTRVGSGPFPTELLGKTGDLLRASGMEFGTTTGRPRRCGWLDIVALKYCCQINGFSSLNLTKLDVLTGLKEVKLGIAYCTEDGKEIESFPADLDLLEKIKVKYEVLPGWEDDISSVRNYSDLPETARLYVERIEELVGIPVHYIGVGPGRDALIYK
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase 2, chloroplastic, AMPSase 2, AdSS 2, IMP--aspartate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUOD_METPB
Sequence: MSEHNIRNFSINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLIEHKTYLQATPYFDRLDYVSPMNQEHAFCLAIERLAGIEVPRRAQLIRTLFCEIGRLLSHLLNVTTQAMDVGALTPPLWGFEEREKLMIFYERASGARLHANYFRPGGVHQDLPPALIDDIEAFCDPFLKVVDDLDNLVMANRIFKQRNVDIGIVSVDEAMAWGFSGVMVRGSGIPWDLRKSQPYECYEEMDFDIPVGKNGDTYDRQVIRMEEMRESVKIMRQCCAKLREPSGQGPIASIDGKFAPPPRREMKRSMEALIHHFKLYTEGFHVPEGEVYAAVEAPKGEFGVYLVSDGTNKPYRCKIRAPGFAHLQAMDWMCRGHLLADVSCVLGTLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BOP1_DROYA
Sequence: MTKKLALKRKGKDAEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEDDDEEEGSSDEEGEEDEEKDSKSKQADDKPSSSGAASKKAPTTELSKRDTSKPEYQDSDTSDEEDIRNTVGNIPMHWYDEYKHIGYDWDAKKIIKPPQGDQIDEFLRKIEDPDFWRTVKDPLTGQDVRLTDEDIALIKRIVSGRIPNKDHEEYEPWIEWFTSEVEKMPIKNVPDHKRSFLPSVSEKKRVSRMVHALKMGWMKTTEEVEREKQAKRGPKFYMLWETDTSREHMRRIHDPVSAPKRDLPGHAESYNPPPEYLFDAKETKEWLKLKDEPHKRKLHFMPQKFKSLREVPAYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDLQPFPTVESMVYRGHTDLVRSVSVEPKGEYLVSGSDDKTVKIWEIATGRCIRTIETDEVVRCVAWCPNPKLSIIAVATGNRLLLVNPKVGDKVLVKKTDDLLAEAPSQDVIESERIKTAVQWSNAEADEQEKGVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRSALIHQLSKRRSQIPFSKSKGLIQFVLFHPVKPCFFVATQHNIRIYDLVKQELVKKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDLSTKPYQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYNDLLQNPLIVPLKKLQTHEKRDEFGVLDVNWHPVQPWIFSTGADSTIRLYT
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: Y3358_GEOTN
Sequence: MANEFRVCDDCKAPNLKTLLPRLKKLDPDAVIKIGCQSYCGPGRKKTFAFVNNRPVAALTEDELIDKIAERLKSR
What are the official names of this protein?
UPF0741 protein GTNG_3358.
What is the protein family that this protein belongs to?
Belongs to the UPF0741 family.
Protein: Y2280_MYCTU
Sequence: MSEMTARFSEIVGNANLLTGDAIPEDYAHDEELTGPPQKPAYAAKPATPEEVAQLLKAASENGVPVTARGSGCGLSGAARPVEGGLLISFDRMNKVLEVDTANQVAVVQPGVALTDLDAATADTGLRYTVYPGELSSSVGGNVGTNAGGMRAVKYGVARHNVLGLQAVLPTGEIIRTGGRMAKVSTGYDLTQLIIGSEGTLALVTEVIVKLHPRLDHNASVLAPFADFDQVMAAVPKILASGLAPDILEYIDNTSMAALISTQNLELGIPDQIRDSCEAYLLVALENRIADRLFEDIQTVGEMLMELGAVDAYVLEGGSARKLIEAREKAFWAAKALGADDIIDTVVPRASMPKFLSTARGLAAAADGAAVGCGHAGDGNVHMAIACKDPEKKKKLMTDIFALAMELGGAISGEHGVGRAKTGYFLELEDPVKISLMRRIKQSFDPAGILNPGVVFGDT
What are the official names of this protein?
Uncharacterized FAD-linked oxidoreductase Rv2280.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: YR752_MIMIV
Sequence: MDSWNCTYCGLEDCDHLNSVVVPKQTNTYWPEPESHKLLQENDLFVISGIDCSFRIDKNVVPKNSILFSKMTSQCFTGTNRFDLPLSQGAMKFIYWFFFDEISKNEIVYKSEFCWIDPISENNQNKVHYINEKDLEYICFAETIKHIYSDMLISDDSDLLTVPKVHGFLCPTRAFVRVLSEYLCFPHRLEKFAMISLEQDRNETRKIHQRIMRTY
What are the official names of this protein?
Uncharacterized protein R752.