PharMolix/UniProtQA huggingface dataset:
Protein: GUF1_LACTC
Sequence: MRRLRSLYLQSSICFRRFNHYSAKDTEALQRRLEQIPIENYRNFSIVAHVDHGKSTLSDRLLEFTGVIKAGDSNRQVLDKLEVERERGITIKAQTCTMFYYDKRRNKDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFYLAYSMNLKLIPVINKIDLDSANIPQAEAQIESTFELPRAEIIRVSAKTGINVKEDLLPAIIDRIPPPTGVGKKPFRALLVDSWYDSYLGVVLLVNIVDGVVKKGDRVVSAQTGKKYEIKELGIMYPDKVSMGCLRTGQVGYIVPGMKESKDAKIGDTIMHVGKESVTEVLDGFEDPKPMVFVGAFPADGTEFKSLDEDITRLVLNDRSVSLQRESSNALGQGWRLGFLGSLHASVFKDRLEKEYGSKLIITQPTVPYVIKFTNGEEKIITNPDDFPDLSLRKTRIDSLQEPYVEAIITLPQEYLGAVIKLCENNRGIQKEITYLNVTGQVLLKYEMPLAHLVDDFFGKLKSVSRGYGSLDYEDIGYKASDIVKLELVLNGKSVDALAQVMHRSQVERVGRKWAKKFKEYVKSQLYEVVIQARANNKVIARETIKARRKDVLAKLHASDVSRRKKLLVKQKEGKKQMKSVGNIQINQEAYQAFLRR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ZIF1_CAEEL
Sequence: MSECSASTSQLSTFCVNEIPWKLVPQTCDEFSEYEFIDEKYRRLSDVESFVWKWSPCGRYGIDLPGGRDVINQQLRDRMAVFDLHTNKWTLYTMDRGAFEIPRVCFLYWARNDIIGTITLVKDYEAGPDDEIPLKFKQSFFYVSHETQTLVYSGSCKYRTNKTIVASYWYHIFENRRGEPFIDHNNYLWLVFSNGVDSLILLPFIPTSTCFKAKCVSFDMNDIVSQFTGIRVFLDPFVSSHYVPWVYRNDVNFFIRIDSHSFIEEQNRDYGLDPQIDNPETKPHRGVFQLRVNLKDVIEKGEKDAIHAVNPETIETRFNRGDIELWRKISDELRQEHQSIAQHGKMVVVQRWSHFTVDMGLSKKMRTRVADLDARDYCCSHKPRNSSFCCIDLDSERIKAVDALILGTDVVLPHPSGSVFLFRYKENYGMSYCELPFFQPLSLKLKCIQVLKESVEIDPSYYRIKCCLKMQEELEKETAENLCTINIQQ
What is the function of this protein?
Probable substrate recognition component of a CBC (Cul2-ElonginB-ElonginC) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Ensures germline precursor cell asymmetry by targeting germline proteins for destruction if expressed in non-germline cells.  This process also requires elc-1, cul-2, rbx-1 and ubc-2.
What are the official names of this protein?
Zinc finger-interacting factor 1, Protein zif-1.
Protein: SAT_BACC0
Sequence: MSTVNELVNLVDETYDISQIEKEIGLDNIALSDLELLATGGYSPLTGFLGKKDYDSVVETLRLDNGSVWSIPITLPVTEEVAKSLKSGEEVKLVNGGNVYGVIQIEDIFVPDKEKEALLVYKTTDEAHPGVKKLYERPNVYVGGAIVLTKRFENNPFPSYHLDPIETREEFKKRGWKTVVGFQTRNPVHRAHEYIQKSALEIVDGLFLNPLVGETKSDDIPADVRMESYEVLLQNYYPKDRVFLSVFPAAMRYAGPREAIFHALVRKNFGCTHFIVGRDHAGVGDYYGTYEAQEIFTNFTVEELGITPLFFEHSFYCTKCEAMASTKTCPHGKEDHVILSGTKVRELLRNGEIPPSTFSRKEVVEVLIKGLKKEVVTE
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: CMOA_SYNC1
Sequence: MTKDSLFSRPQKPVPPFEFNASVVEVFDDMLNRSVPCYRELIHRQAQLAAHFYQPKTRIYDLGCSTGNLDLAICSAMDAARPFELVGVDNSEPMLKVCRERMRETPPEANISFACSDIRNLEMSNASVIILNLTLQFIPPADRQNILNRIFQALVPGGILLLTEKTVHAHAGLSELQQDFYYRFKAENGYSQMEISQKREALENVLIPETMESHRKRLDQAGFKAVDTWLKWFNFASFIALKEKS
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RIBB_SHIBS
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: PABP_USTMA
Sequence: MSSTESPVPAAAAPAEAVPASTPAPAAEQPAVGNGEQRNNADAANNTSLYVGELDPSVTEAMLFEIFSMIGTVASIRVCRDAVTRRSLGYAYVNFLNAADGERAMEQLNYSLIRNRPCRIMWSQRDPALRRTGQGNIFIKNLDAGIDNKALHDTFAAFGNILSCKVATNETGSLGYGFVHYETAEAAEAAIKHVNGMLLNDKKVYVGHHIPRKERQAKIEETRANFTNVYAKNVDPEVTDDEFEKLFTKFGKITSCVLQRDEDGKSKGFGFVNFEDHNEAQKAVDELHDSDFKGQKLFVARAQKKSEREEELRRSYEAAKNEKLAKFQGVNLYLKNIPESYDDERLREEFAPFGAITSCKIMRAPSGVSRGFGFVCYSAPEEANKAVSEMNGKMLDNRPLYVALAQRKDVRRQQLEAQIMQRNQLRLQQQAAAQGMGYPGPGMYYPQPGAFPGQPGGMVPRPRYAPAGMMPQGMPMAPYGQPGQFPAGMMPQGYRPARPPRGAPNAAGGPAPPAGARPPTGVNGAPRPAGQPVPGQPMPRGPAARPAGRPEADQPGALTAAALAKASPEEQKQMLGEAIYPKVAASQPELAGKLTGMILELPVTELLHLLEESEALDAKVNEALEVLKEYQQNDSAGAEAEANAEAPKTEA
What is the function of this protein?
RNA-binding protein involved in the formation of polar-growing hyphae which is essential for infection by the plant pathogen (PubMed:15643068).  Component of endosomal mRNA transport that regulates polarity of the infectious hyphae by transporting a broad spectrum of cargo mRNAs from the nucleus to cell poles (PubMed:19494833, PubMed:25985087, PubMed:31338952).
What are the official names of this protein?
Polyadenylate-binding protein 1, PABP, RNA-binding protein RRM12.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Endosome. Cytoplasm. Note=Shuttles with endosomes along microtubules.
Protein: FLS_MATIN
Sequence: QVPVVDLSCPDEELVARTVVKASEDWGVFQVVNHGIPTELIQRLQKVGREFFELPEAEKRSCAREAGSVEGYGRRIELDIKKRKGIVDQIYLSTWPPSSVNYRYWPKSPPDYREVNEEYARHVKTLSEKIMEWLSEGLGLGREAIKEVNGCWYVMNINHYPPYPHSDSFNGLEPHTDINGLTLIITNEIPGLQVFKDDHWIEVEYIPSAIIVNIGDQIMMLSNGKYKNVLHKTTVDKEKTRMSWPVLVSPTYDMVVGPLPELTSEDDPPKFKPIAYKDYVHNKITFLKNKS
What is the function of this protein?
Catalyzes the formation of flavonols from dihydroflavonols.  It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin.
What are the official names of this protein?
Flavonol synthase/flavanone 3-hydroxylase, FLS.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_LISIN
Sequence: MTIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALLEAKEENHRLRTEIENELRGRRTETQKAENRLLQREENLDRKDTSLSKREATLERKEESISKRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIILNQVEEELTHDTAIMVKESENRAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIREVGEQATFEVGIHSIHPDLIKILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTLAKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVINSIASHHGDTEATSVIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTIDDLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS2_BIFAA
Sequence: MAQITMSDMLKAGLHFGHQTRRWNPKMKQFILTQRNGIHIINLFKSLDMIDKAYDFIKATVAHNGTVLFVGTKKQAQEAVSAQATRVNMPYVSERWLGGMLTNFQTVSKRVSRLKELEEMDFTDVHGSGLTKKELLLLEREKDKLAKQLGGIRNMNRTPSAMFVVDVNKEALAVEEAHKLGIPVVAIVDTNADPESVEYPIAANDDAIRGIELLTSLMADAVAEGLLERSGKAAKAEGEAEQPMAAWEKELLTEGAPAAEAPAEAEGETKAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NFUA_HAEIN
Sequence: MEQATQQIAISDAAQAHFRKLLDTQEEGTHIRIFVVNPGTPNAECGVSYCPPNAVEESDIEMKYNTFSAFIDEVSLPFLEEAEIDYVTEELGAQLTLKAPNAKMRKVADDAPLIERVEYVIQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSMVDVTLKDGVEKQLVSLFPNELKGAKDITEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: DLHH_AZOBR
Sequence: MTDISIPAGDDGSFSAYVAKPAGGGPAPGLVVIQEIFGVNQVMRDLCDAFAAQGWLAVCPDLFWRQEPGVQITDKTQEEWNRAFALMNGMDQDKRWTTSRPPCRGCARIRIAPAKRVGRLLLGRRLAFMMAARSDSDANVSYYGVGLDGLVGEAASITKPLLMHIAEKDQFVPAEAREKVLAAVKGNPNVTAHVYPGVDHAFARAGGAHFEPEAAELANGRTAAFFKQHLG
What are the official names of this protein?
Putative carboxymethylenebutenolidase, Dienelactone hydrolase, DLH.
What is the protein family that this protein belongs to?
Belongs to the dienelactone hydrolase family.
Protein: WTF4_SCHPO
Sequence: MKNKDYPLRSSMDELSTKNDNEIDLEKGPLPEYNSEDGSTLPPYSEIWKYIKTVSEDSSTGPTEIANPNVERRQEFKDSHPNIYSLLRLLISVLAVIVVFFTAWVCVNPLEKSIFGKVAFSVTIGITCPIVFIVIFCFFETWTQAVAQCIKVTVIFLAQCVKVTAVFLAKCVKVIAVGLYNSKKDLVVTIWLAWVVICFILFGCVKDGRLNLNKALICSTCSISAALFFILLLVCIPIWTLKHMLFGLFQVLGVQSCVVIVTKGLMYLFDKHIDATGYEIEASSLFVIGNFLFFYEMERPGALKRMPKFIGNGIASFLGGLGNAFGGIGNAFGGIGNAIGRIGNAFRGANDNNDIPLGEMDVESEV
What is the function of this protein?
Forms toxic aggregates that disrupt spore maturation.
What are the official names of this protein?
Meiotic driver wtf4.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
[Isoform 1]: Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Note=Contained within spores expressing the isoform and localizes isoform 2 to the vacuole. SUBCELLULAR LOCATION: [Isoform 2]: Ascus epiplasm. Cytoplasm. Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes in trans to all spores within an ascus. Localization to the spore vacuole is dependent on isoform 1.
Protein: LEXA_BURCM
Sequence: MTKLTARQQQVFDLIRRAIERSGFPPTRAEIAAELGFSSPNAAEEHLRALARKGVIELAAGASRGIRLLGIEDAPHQFTLPHAGLMQLSLPLVGRVAAGSPILAQEHISQHYACDPALFTSKPDYLLKVRGLSMRDAGILDGDLLAVQKRTEAKDGQIIVARLGDDVTVKRLMRRPGGLELIAENPDYENIFVKAGSAEFALEGIAVGLIRSGEL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HEM3_GEODF
Sequence: MALKQLRIGTRASQLALWQANWVKSELEQRYPGMEVSLVKIKTIGDKILDVPLAQVGGKGLFVKEIEEAMLRGDIDIAVHSMKDVPTEFPEGLGLHCITEREDPRDAVISRGTKFADLPQGAKIGTSALRRQAQLLKVRPDMEMVIIRGNVETRINKLETEKLDAVILAAAGLKRLGFTEKVAEYLPTDLSIPAIGQGALGIECRLDNEEVKQTIDFFNHPATAYAVRAERALLWRCEGGCQVPIAAFGEVTGSDLKLVGFIASVDGKTSVRGTITGPAADCEKLGIKLAEQLLADGGHAILAEVYQREVSREKEIPV
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YC21B_YEAST
Sequence: MESQQLHQNPRSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQDKQSKLDQFNYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAPKEVDADISEYNILPSPVRSRTPHIINKESTEMGGTVESDTTSPRHSSTFTARNQKRPGSPNDMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSESTTPIISIETKAVCDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHQSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty2-C Gag-Pol polyprotein, TY2A-TY2B, Transposon Ty2 TYA-TYB polyprotein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TM218_RAT
Sequence: MAGMVLGVGAGVFLLALLWVLVLLLCVLLCRASGIARFSIIFVFLGALIITTVLLLFPRASEFPAPQGEMKIVDAFFIGRYVLLAFLSAVFLGGLFLLLTHHVLEPIYAKPLRSC
What is the function of this protein?
May be involved in ciliary biogenesis or function.
What are the official names of this protein?
Transmembrane protein 218.
What is the protein family that this protein belongs to?
Belongs to the TMEM218 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: DHB11_RAT
Sequence: MKYLLDLILLLPLLIVFCIESFIKRLIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQVHPFVVDCSQREEIYSAVRKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNHGHVVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGCTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVEHLMHGILTNQKMIFVPGSIALLTVLERVFPERFLDVLKRRINVKFDAVVGYKDK
What is the function of this protein?
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis.  May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it.  Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
What are the official names of this protein?
Estradiol 17-beta-dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase 11, 17-beta-HSD 11, 17bHSD11, 17betaHSD11, 17-beta-hydroxysteroid dehydrogenase XI, 17-beta-HSD XI, 17betaHSDXI, Dehydrogenase/reductase SDR family member 8.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lipid droplet. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation.
Protein: RL2_GEOTN
Sequence: MAIKKYKPTSNGRRGMTVLDFSEITTDQPEKSLLAPLKKKAGRNNQGKITVRHQGGGHKRQYRIIDFKRDKDGIPGRVATIEYDPNRSANIALINYADGEKRYILAPKNLKVGMEIMSGPNADIKVGNALPLENIPVGTLVHNIELKPGRGGQLVRAAGTSAQVLGKEGKYVIIRLASGEVRMILGKCRATVGEVGNEQHELVNIGKAGRARWLGIRPTVRGSVMNPVDHPHGGGEGKAPIGRKSPMTPWGKPTLGYKTRKKKNKSDKFIIRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ARGD_XYLFT
Sequence: MSAVSESVLSLSRYYLPVYRPCQVVLVRGQGSRVWDEQGRDYLDLAAGIAVCCLGHCDPDLVAALVEQAGRLWHTSNVFYSEPSLRLAQELVDVSRFAERVFLCSSGTEANEAAIKLVRKWAAAQGRLPEHRTIVTFRGSFHGRTLGAVTATAQPKYQEGYEPLPGGFRYVDFNHIEALEAAMVGGDVAAVMLEPIQGEGGVMPIAPGYLAQVRALCDRYGALLVLDEIQCGMGRTGTLFAYWQEEVVPDIVTLAKGLGGGFPIGAMLAGPKVAEVMQFGAHGTTFGGNPMAAAVARVALRKLASVEIAANVQRQSVALRAGLEEISEAFGGVFTQVRGRGLMLGAVLAPLYAGQASAILEVAAEHGVLLLQAGPDVLRFVPALNVSDEELADGLVRLRAALGDYVSRCRG
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOWR_DROMO
Sequence: MSFTGKLAELLARPNQDPAGGPEAPWYLKYGSRVLGIVAAFFAILFGLWNVLSIIGLSVSCMLVAGIIQMLAGFVVMALEAPFCFVCIEKVNDVSKMVDAKPMFFRAGLYCAMAVPPIFMCFGLASLFGSGLIFATGAVYGMMALGKKASAADMRAAAAQTSYGGNAASTTSDRAGIVSNAQPFSFTGAVGTDSNV
What is the function of this protein?
A calcium channel that regulates synaptic endocytosis and hence couples exo- with endocytosis.  Required in the nervous system and necessary in photoreceptor cells (By similarity).
What are the official names of this protein?
Calcium channel flower.
What is the protein family that this protein belongs to?
Belongs to the calcium channel flower family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Upon fusion of the synaptic vesicle with the presynaptic membrane, protein is present in the periactive zones, where endocytosis is known to occur.
Protein: CITD_SALAR
Sequence: MKINQLAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGEAIRATILEVLSRYDVRGVQLNVDDKGALDCILRARLETLLARASGIAALPWEDRQ
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTB_BURCM
Sequence: MNAQEANFDGLVGPTHNYAGLSFGNVASLNNEKSAANPKAAAKQGLRKMKQLADLGFAQGVLPPQERPSLRLLRELGFSGKDADVIAKAAKQAPELLAAASSASAMWTANAATVSPSADTGDGRVHFTPANLCSKLHRAIEHDATRRTLSTLFADPAHFAVHEALTGTPALGDEGAANHTRFCAEYGKPGVEFFVYGRAEYRRGPEPKRFPARQTFEASRAVAQRHGLDETATVYAQQDPDVIDAGVFHNDVISVGNRDTLFTHERAFVNKQAIYDTLTATLDARGARLNVIEVPDAAVSVNDAVTSYLFNSQLLSRADGSQVLVVPQECRENAKVAAYLDELAAGNGPIRDVLVFDLRESMKNGGGPACLRLRVVLNDAERAAVTSNVWMNDTLFASLDAWIEKHYRDRLAPEDLADPTLLDESRTALDELTQILRVGSLYDFQR
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: TILS_PHOLL
Sequence: MANIDERLFVTLAKQLGEYKKILVGFSGGLDSSVLLHLLVNWRNQHNQKIQLRAIHIHHGLNLKADQWIEHCQLICDDWQVEFHSARVTIDARQKGIEAAARDARYQVFKSELQKDEVLVTAQHLDDQAETFLLALKRGSGPAGLASMPSIAVFADTLLLRPLLDYSRNELEKYASKHRLNWIEDDSNQDDRYDRNFLRLHIMPLLNQRWSHFPKAAARSASLCGEQEQLLDELLNESLKELITQDGALGIVSLAVCSEAKRNALLRRWFGYHGMKMPSREQLNRLWYEVALARTDAEPRLQFGKYDVRRYKQKLWLVPQWQSLRETILEWDICNTLVLPDRLGELNIADRGIQVRVPADNERVTIRFGVQGMISIVGRQHSRHSKKLWQELGVAPWLRERIPLLYYNEQLIAALGVFVTKESEAAEGRKMLTMNWHKTLLK
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_STRPJ
Sequence: MSKGFLVSLEGPEGAGKTSVLEALLPILKEKGVEVLTTREPGGVLIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSSVAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDLEGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CSK2B_BOVIN
Sequence: MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
What is the function of this protein?
Regulatory subunit of casein kinase II/CK2.  As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).  Participates in Wnt signaling (By similarity).
What are the official names of this protein?
Casein kinase II subunit beta, CK II beta, Phosvitin.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: RS16_STRM5
Sequence: MVKIRLTRGGAKKRPFYHIIVTDVRSARDGRNIERVGFYNPVAQGGEKRIELDLARVDHWVKNGAQPTEKVRNLIKEATKSQAAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MED11_SCHPO
Sequence: MTNSDDDLFSEKSTSSDTQQVQNILELEAKIPDILSSAGKCIEAIQLNNSLEDFRKYSKEFLETVEFISTGLRRQALELEKAEVPVVSLQPKKRYASTPLSNLIFDQSSKLM
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex (PIC) with RNA polymerase II and the general transcription factors.  The essential med11/22 heterodimer specifically functions in promoting stable PIC formation (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 11, Mediator complex subunit 11.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 11 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RR18_PINTH
Sequence: MDKPKQSFRRHFKPIRRRFKPIRRYLKPIRRHLSPIRSGDRIDYKNMSLISRFISEQGKILSGRVNRLTSKQQRLMTNAIKRARILSLLPFLYNEN
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.