PharMolix/UniProtQA huggingface dataset:
Protein: PSBH_SACHY
Sequence: MATQTVEDSSRPKPKRTGAGSLLKPLNSEYGKVAPGWGTTPFMGVAMALFAIFLSIILEIYNSSVLLDGILTN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LPTD_XANCP
Sequence: MRRALRLLPLPLSIAICLPAMAADKPLNWGLCPAVDPLPGFDGAPAADPKAAEIRQQLPTDIEGDQLSGTSTTPQYQGNVALKRGDQFLGADNLRMDTETGNYIAEGNVRYQDTSFRMVADRAEGNQDTDSHKVTNIQYQLVDRRGNGGAESVDLQGQVGQMHRSTYTTCDPSQPIWRVRAPEIDVDNDEGFGTARNAVLQIGKVPVLYFPWFKFPIDDRRMTGLLFPQFGLSGRNGFDYLQPIYLNLAPNYDATLLPRYMSRRGFMFGTEFRYLYDGGRGEITGNYLPNDNLRKKDRGSVFYSGYHNVNRYWQARSSISWVSDTRYVEDFTSRINGMGSASSIQSTVGIYGTGETWTAGLMADRWQLTDYTLDERSLPYNRQPRAYFTWEKPFGIFEAGVYAEAVRFTHDDSYLVQPPRDGNTNGDDGDDYVRTNIRNQEYGSGSRLDLKPYISMPLSGSAWFLTPTVAWRYTAYQLDSTLANTAPLTGDRSPTRSLPIASLDAGLYFDRETSLFGTKYLNTLEPRAYYLYVPYREQNDLPVFDTRPFTFSYGQLFRDTRYTGADRQNDANQLTLAVTSRWLRQDDGREKLSLSAGQILYFNDSLVTINNSTNAAAGSEQTIEQGKSAWVADANYMINDRWSMGATYQWNPNSRKEDLASLRTRYLLNNDGIINLAYRYRRNLIDESDQLKQADFSFLYPINPTWSAVGRYYYSLLDRKPLEIIGGVQWDSCCLAVRALVRRFVRNRDGEMDNSIQFEFVLKGLSSFGQNTDRTLRRAILGYYRDDLYLVPPSNTTTNPDDYDPNLIP
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: LEUC_AGRRK
Sequence: MSAPRTLYDKIWDDHLVDSQDDGTCLLYIDRHLVHEVTSPQAFEGLRMTGRKVRAPEKTLAVVDHNVPTSPDRHLGIKNEESRIQVEALATNAAEFGVQYYSASDKRQGIVHIIGPEQGFTLPGMTIVCGDSHTSTHGAFGSLAHGIGTSEVEHVLATQTLIQKKAKNMLVRVDGQLPAGVTAKDIILAIIGEIGTAGGTGYVIEYAGEAIRALSMEGRMTICNMSIEGGARAGLIAPDETTFEYIKGKPRSPTGEALEQAIAYWKTLQTDEGAHYDRVVVLDAAALPPIVSWGSSPEDVVSVQGIVPNPDEIQDENKRTSKWRALDYMGLKPGTPMTEINIDRVFIGSCTNGRIEDLRAVAKVVEGKTVASTVDAMIVPGSGLVKEQAEAEGLDKIFKAAGFDWREPGCSMCLAMNDDRLKPGERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDIREWN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SECB_YERPS
Sequence: MSEQNNTEMAFQIQRIYTKDISFEAPNAPQVFQQDWQPEVKLDLDTASSQLAEDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSVAGIEGTQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAEGEVEGVEQRQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_BIFLS
Sequence: MSQTAYRTHHATEVTEALVGQKVTLAGWVDRRRDHGGVAFIDLRDSTGLVQVVIYDEDMARPLRSEFVIQITGEVRLRPDGNENTHLATGKIEVVAETIEILAKSDALPFQVSTALENESENKLPGEDVRLKYRYLDLRRPSMQHNLKLRSDMAKAARHALEDMDFTEVETPTFIKSTPEGARDFVVPARLVPGSWYALPQSPQLLKQLLMVSGVERYYQLARCYRDEDFRADRQPEFTQLDMEMAYVDQEDVMAMTEKVIAAIWKSAGYEVQLPLPRITWKDAMDKYGSDKPDLRFGNPLVELTEYFKNTPFRVFQAPYVGAVVFKGGAATPRRQFDAWQDWARQRGAKGLAYVVFGENGELKGPVAKNLSDEERNGLREAVGAEEGDAVFFAAGSRESAQLLLGAVRVELASREGLLDPKKFAFTWVVDFPLFKPTDDPDDDDVAVGHSKWTSMHHPFTMPSKDWIDKFDKDPEHAMSDSYDIVCNGEEMGGGSVRIHRDDIQARVLDVLGITKEEADEKFGFLLEAFKYGAPPHAGLALGWDRTVSILAGADSIRDVIAFPKAGGGRDPLTGAPAPISDEQRAETGVDYDPDADEN
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SX15F_RHOJU
Sequence: MKILIFIIASFMLIGVECKEGYPMGRNGCKIPCAINDNICKVECQAKWKQSDGYCYSWGLSCYCTNLLEDAEVWDSSNNKCVG
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Putative beta-neurotoxin RjAa15f.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ELL3_BOVIN
Sequence: MEGPQELLSGKLRLCFTPAARTSLLLLKLNDAALRALQECHRQQVRPVIAFQGNRGYLRLPGPHWSCLFSFIVSQCGQEGPGGPGLDLVCQCPGRSGPNRLHCLGPLRERLTIWAAMDSIPAPSSLQRHNRTEDARDRESWQNVGDYPEADTISQSQMGLEEVPDPLASSQGQSLPGSSREHMAQWEVRNQTLLPNRDPDQALPPSASQKHVDKKRPAPAAMVELKQKRLRTLAPSPLQGLPSQDLQEEDWEQEDKDEDMGPRLEHSPSVQADSESLSPEEVPDYLLQYRAIHSAEQQHAYEQDFETDYAEYRILHARVAAASQRFIELAAEMNNVQRGTPEHKALEEKIVQEYKKFRKRYPGYREEKRRCEYLHQKLSHIKGLILEFEEKNRGS
What is the function of this protein?
Enhancer-binding elongation factor that specifically binds enhancers in embryonic stem cells (ES cells), marks them, and is required for their future activation during stem cell specification.  Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.  Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.  Does not only bind to enhancer regions of active genes, but also marks the enhancers that are in a poised or inactive state in ES cells and is required for establishing proper RNA polymerase II occupancy at developmentally regulated genes in a cohesin-dependent manner.  Probably required for priming developmentally regulated genes for later recruitment of the super elongation complex (SEC), for transcriptional activation during differentiation.  Required for recruitment of P-TEFb within SEC during differentiation.  Probably preloaded on germ cell chromatin, suggesting that it may prime gene activation by marking enhancers as early as in the germ cells.  Promoting epithelial-mesenchymal transition (EMT) (By similarity).
What are the official names of this protein?
RNA polymerase II elongation factor ELL3.
What is the protein family that this protein belongs to?
Belongs to the ELL/occludin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PVK21_BLAOR
Sequence: GSSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.1, Pea-PVK-2-like peptide, Periviscerokinin-3, BlaOr-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPP_PHOLL
Sequence: MNRTKIVLGAVVLASTLLAGCSSTAKVDQLTSDIQTLNAKVDQLSNDVNAVHTDVQAAKDDAARANQRLDNQVRSYKK
What is the function of this protein?
A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes.  The only protein known to be covalently linked to the peptidoglycan network (PGN).  Also non-covalently binds the PGN.  The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
What are the official names of this protein?
Major outer membrane lipoprotein Lpp.
What is the protein family that this protein belongs to?
Belongs to the Lpp family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side. Secreted, cell wall; Peptidoglycan-anchor. Note=Attached via its lipidated N- terminus to the inner leaflet of the outer membrane. Attached to the peptidoglycan network (PGN) via its C-terminus.
Protein: FBPC_ECO57
Sequence: MSQKNFVELRNVTKRFGSNTVIDNINLTIPQGQMVTLLGPSGCGKTTILRLVAGLEKPSEGQIFIDGEDVTHRSIQQRDICMVFQSYALFPHMSLGENVGYGLKMLGVSRSEVKQRVKEALAMVDLEGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMRDKIRELQKQFNITSLYVTHDQSEAFAVSDTVLVMNKGHIMQIGSPQDLYRQPASRFMASFMGDANLFPANFSEEYVDIYGYRLPRAAHFPVQGSGTVGVRPEAITLSNHGEESQRCVIRHVAYMGPQYEVTVEWHGQEILLQVNATRLQPDIGEHYYLEIHPYGMFVLADAA
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CDC26_BOVIN
Sequence: MLRRKPTRLELKLDDIEEFESIRKDLETRKKQKEDVDIVGGSDGEGAIGLSSDPKSREQMINDRIGYKPQPKPNNRSSQFGNFEF
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit CDC26, Cell division cycle protein 26 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC26 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y190_HELPY
Sequence: MKIFLVFLSVFFFNGCFGLVYKTPISSSPISYDPYTTPIGSLYAEKLKENPNHSAAILLEDGFDALLHRVGLIRMSQKSIDMQTYIYKNDLSSQVIAKELLNAANRGVKVRILLDDNGLDSDFSDIMLLNFHKNIEVKIFNPYYIRNKGLRYFEMLADYERIKKRMHNKLFIVDNFAVIIGGRNIGDNYFDNDLDTNFLDLDALFFGGVASKAKESFERYWRFHRSIPVSLLRTHKRLKNNAKEIAKLHEKIPISAEDKNQFEKKVNDFIDRFQKYQYPIYYGNAIFLADSPKKIDTPLYSPIKIAFEKALKNAKDSVFIASSYFIPGKKMMKIFKNQISKGIELNILTNSLSSTDAIVVYGAWERYRNQLVRMGANVYEIRNDFFNRQIKGRFSTKHSLHGKTIVFDDNLTLLGSFNIDPRSAYINTESAVLFDNPSFAKRVRLSLKDHAQQSWHLVVYRHRVIWEAVEEGILIHEKTSPDTSFFLRLIKEWSKVLPEREL
What are the official names of this protein?
Uncharacterized protein HP_0190.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PXL2B_BOVIN
Sequence: MSTVDLARVGACVLKHAVTGEAVELRNLWQEQACVVAGLRRFGCMVCRWIARDLSNLKGLLDQHGVRLVGVGPEALGLQEFLDGGYFAGELYLDESKQFYKELGFKRYNSLSILPAALGKPVREVAAKAKAVGIQGNLSGDLLQSGGLLVVAKGGDKVLLHFVQKSPGDYAPLESILQALGISAEVGPSELPQCDEEACSR
What is the function of this protein?
Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor.  Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity).
What are the official names of this protein?
Prostamide/prostaglandin F synthase, Prostamide/PG F synthase, Prostamide/PGF synthase, Peroxiredoxin-like 2B.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TCYJ_ECOLI
Sequence: MKLAHLGRQALMGVMAVALVAGMSVKSFADEGLLNKVKERGTLLVGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRIDVVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTIKTADDLKGKKVGVGLGTNYEEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEAFSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK
What is the function of this protein?
Part of the ABC transporter complex TcyJLN involved in L-cystine import (PubMed:25139244, PubMed:20351115, PubMed:25837721, PubMed:26350134).  This high affinity cystine transporter is involved in resistance to oxidative stress by forming a L-cysteine/L-cystine shuttle system with the EamA transporter, which exports L-cysteine as reducing equivalents to the periplasm to prevent the cells from oxidative stress.  Exported L-cysteine can reduce the periplasmic hydrogen peroxide to water, and then generated L-cystine is imported back into the cytoplasm via the TcyJLN complex (PubMed:20351115, PubMed:25837721).  Functions at low cystine concentrations (PubMed:26350134).  The system can also transport L-cysteine, diaminopimelic acid (DAP), djenkolate, lanthionine, D-cystine, homocystine, and it mediates accumulation of the toxic compounds L-selenaproline (SCA) and L-selenocystine (SeCys) (PubMed:25139244, PubMed:26350134).  Binds cystine and DAP (PubMed:4564569, PubMed:8450713).
What are the official names of this protein?
L-cystine-binding protein TcyJ, CBP, Protein FliY, Sulfate starvation-induced protein 7, SSI7.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y2336_SHEDO
Sequence: MAIQSKYTNTQVEALISELLAVLAKHQAPTDLSLMVLGNCVTHLLENKVPSESRQAVAEQFAKALVKSVK
What are the official names of this protein?
UPF0352 protein Sden_2336.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: HETI_NOSS1
Sequence: MLQHTWLPKPPNLTLLSDEVHLWRIPLDQPESQLQDLAATLSSDELARANRFYFPEHRRRFTAGRGILRSILGGYLGVEPGQVKFDYESRGKPILGDRFAESGLLFNLSHSQNLALCAVNYTRQIGIDLEYLRPTSDLESLAKRFFLPREYELLRSLPDEQKQKIFFRYWTCKEAYLKATGDGIAKLEEIEIALTPTEPAKLQTAPAWSLLELVPDDNCVAAVAVAGFGWQPKFWHY
What is the function of this protein?
Probably activates the acyl carrier protein (ACP) domain of HetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue.  May be required for maintaining vegetative growth and probably acts via HetN to inhibit differentiation.
What are the official names of this protein?
4'-phosphopantetheinyl transferase HetI.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
Protein: PA3B_ODOVE
Sequence: MFTLKKPLLLIVLLGIISLSLCEQERNADEDEESEIKRGIFPKIIGKGIKTGIVNGIKSLVKGVGMKVFKAGLSNIGNTGCNEDEC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Palustrin-3b, pal3b.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CG031_RAT
Sequence: MEVIHGRPYCCRELEGADILSNTFYSNGLHTPYETTIRPTASEDRYQELRQALPQCRLRWGADREYGGMLPVSLPEEHRPKCEPPRLMSKGHQHYGFGGEIWPKKLPIEQYYYLTQNKKSDLYGNDSLLPKPPNSTVGEICSSYPIEHPYHTHISRGAMFPAFTSPKDLYTGVKARTQQPFPPTLPTKTYDSTILKTRGNPYRYELLDLPTDSKKKALTWPGQSVYYDFPKCVEKNKPVFYPKPPKTFAPNSSVTPWDTMTSAKDANIQRNLERSHWLTSYTHDFTGLGPMSPLELDDYREKELAELTGQIGFDPQPQEKFHPSLKPPRPLDGRIARLIQNQRPLEATVQIPPSCPDCTPRVLCAFHTFIPSSAEMMAMNDHLLSGLTHKNQNIEDKIKEEQRLLSTYALPSSYESKDMGSLFDLHSLPKITDTKKSDDLYWRQLDVKPLPIARSKSNHYIDYEPHKSTYRDPYAMCLNPVRLSKSNILQNKTDMADLTFDNYLRKPEFLGTDIESSDETRPLLNWISRAGVPKHHTNFRDFKNSFSRSMAHKRLHNSIQEEQKDLRDKLQCGMRHQFYGHNSHYFYN
What are the official names of this protein?
Uncharacterized protein C7orf31 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: BHE41_RAT
Sequence: MDEGIPHLQERQLLEHRDFIGLDYSSLYMCKPKRSLKRDDTKDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERSLKSPVQADLDAFHSGFQTCAKEVLQYLARFESWTPREPRCAQLVSHLHAVATQLLTPQVTPGRGPGRAPCSAGAAAASGSERVARCVPVIQRTQPGTEPEHDTDTDSGYGGEAEQGRAAVKQEPPGDPSAAPKRLKLEARGALLGPEPALLGSLVALGGGAPFAQPAAAPFCLPFYLLSPSAAAYVQPWLDKSGLDKYLYPAAAAPFPLLYPGIPAAAAAAAAAAFPCLSSVLSPPPEKAGSAAGAPFLAHEVAPPGSLRPQHAHSRTHLPHAVNPESSQEDATQPAKDAP
What is the function of this protein?
Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes.  Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop).  Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2.  Represses the activity of the circadian transcriptional activator: CLOCK-BMAL1 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes.  Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2.  Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity (By similarity).  Inhibits HNF1A-mediated transactivation of CYP1A2, CYP2E1 and CYP3A11 (By similarity).
What are the official names of this protein?
Class E basic helix-loop-helix protein 41, bHLHe41, Class B basic helix-loop-helix protein 3, bHLHb3, Enhancer-of-split and hairy-related protein 1, SHARP-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SNO3_YEAST
Sequence: MTVVIGVLALQGAFIEHVRHVEKCIVENRDFYEKKLSVMTVKDKNQLAQCDALIIPGGESTAMSLIAERTGFYDDLYAFVHNPSKVTWGTCAGLIYISQQLSNEAKLVKTLNLLKVKVKRNAFGRQAQSSTRICDFSNFIPHCNDFPATFIRAPVIEEVLDPEHVQVLYKLDGKDNGGQELIVAAKQKNNILATSFHPELAENDIRFHDWFIREFVLKNYSK
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of a SNZ isoform.
What are the official names of this protein?
Probable pyridoxal 5'-phosphate synthase subunit SNO3, PDX2 homolog 3, Pdx2.3, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RL1_HAEDU
Sequence: MAKLTKKMKAIKAGVDSTKAYEINEAIALLKQFATAKFVESVDVAVNLGIDPRKSDQNVRGATVLPHGTGRSARVAVFTQGANAEAAKAAGADLVGMEDLAEQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTLNVAEAVKNAKSGQIRYRNDKNGIIHTTIGKVDFSEVQLKENLQALLAALNKAKPTTAKGIFIKKVSVSTTMGAGVAVEQTSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YTUX_AGRVI
Sequence: MVKPGQILRAAVRETAEPLTELAGDSVSSAGRVSAAYHAIRNAIRTNVFPPGYQAAEIEIARQLGMSRTPVHEAMARLQEDGLVRILPKKGIIICALSPADIEEIYEVTIALEGAAASRLAMIDAPVKAEVVALLRDATEAMVAALERNDLPGWAAADERFHETLVACAAQ
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator in the TAR-I ttuE-ttuC' intergenic region, ORFX.
Protein: RL33_BURTA
Sequence: MAKGARDKIKLESTAGTGHFYTTTKNKRNMPEKMEIMKFDPVARKHVAYKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MRGX2_MACMU
Sequence: MDPTTPAWGTESTTMNGNDQALPLLCGKETMISVFLILFIALVGLVGNAFVLWLLGFRMRRNAFSVYVLSLAGADFLFLCFQMTSCLAYLINFFGSISINIPSFFTVMTCAYLAGLSMLSAISTERCLSVLWPIWYRCRRPRHLSAVMCVLLWALSLLLSILEGKFCGFLFSDDDPGWCQTFDFITAAWLMFLFVVLCGSSLALLVRILCGSRSLPLTRLYLTILLTVLIFLLCGLPFGIQWFLILWIWKNSVVLFCHIHPISVVLSSFNSSANPIIYFFVGSFRKQWRLRQPILKLALQRALQDTAEVDHSEGCFSQGTLEMSRSSLV
What is the function of this protein?
Mast cell-specific receptor for basic secretagogues, i. e.  cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core.  Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium.  In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction.
What are the official names of this protein?
Mas-related G-protein coupled receptor member X2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPAN1_BPT7
Sequence: MLEFLRKLIPWVLAGMLFGLGWHLGSDSMDAKWKQEVHNEYVKRVEAAKSTQRAIDAVSAKYQEDLAALEGSTDRIISDLRSDNKRLRVRVKTTGTSDGQCGFEPDGRAELDDRDAKRILAVTQKGDAWIRALQDTIRELQRK
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit.  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans.  Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex.
What are the official names of this protein?
Spanin, inner membrane subunit, i-spanin, Gene product 18.5, Gp18.5.
What is the protein family that this protein belongs to?
Belongs to the T7likevirus i-spanin family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SYA_WOLTR
Sequence: MKLNEIRERFIKFFVRNNHKQVFSSPLIPEHDPTLMFTNAGMVQFKNIFTGIQKTDIKRAVSSQKCLRVGGKHNDLENVGYTTRHHTFFEMLGNFSFGDYFKETAIEFAWKFITEELSLDKNRLSITIYHTDDKSYEIWRKVSGFSNDKIIRIATDDNFWSMGNIGPCGPCSEIFYDYAKPNLQNDDRIVEIWNLVFMEFNKDEEGNLQKLPKKCIDTGMGLERVAAVMQNVYDNYDIDLFSALISKSQEYCGNVENKAAHKIIADHLRAAAFLIAEGVLPGNEGRNYILRRLIRRAVRYIHQLGYNDPLLHRIFPVLIDSTSSAYMGGVYPELIRAKSLIETTLKSEEENFKDTLIKGINLLKKFTTDLKPGDTLSGESAFKLYDTYGFPLDITLDILKERKINFDQKGFDNAMEEQKERARAKWTGSGEKSIEQIWFNLIDKFGKTEFVGYEFSEVKDAKVLVILSSKNEVIDSAKEGEKITIILDKTPFYGESGGQVGDTGSFIIPSITPVLDTKIQKKNDRSCDRITEGIAIVENTNKVNDLYLHRCIVKSGSICKDDIVTASTDKERRQNLRRNHSATHLLHFALRKILGDHVTQKGSLIAPDRLRFDFSHNTQVTRDQLSLIEDMVNSLIRENLSAFTKIQSMNQAIGEGAMALFGKKYGDQVRVVNIGDSKELCGGTHVERTGEIGLFKIITECSIASGVRRIEALTGQEAIDYARDNEINLRKIAELVKAPVNEITSRLSILNQERKESETKIKSLYKKLVSAENIKSIEINGMNFVSHSFTDIPANIVREFTLQQQKPKTVIAFTAMEKNKTVLIVKVSKDLVDKISTKELVSTVTGGVCGENAELTQTGCDSSDIFTAIYSYLTR
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.