PharMolix/UniProtQA huggingface dataset:
Protein: PCP1_STRPN
Sequence: MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVFYKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPIRIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMRAGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase 1, 5-oxoprolyl-peptidase 1, Pyroglutamyl-peptidase I 1, PGP-I 1, Pyrase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_CAMJD
Sequence: MSLIKIDQKAYEYNLRHIAKKIGSFQRLICVFKDNAYGHGAKLLAPLAKNLGVSFVAVKSEEEAREIEEFFENILILSHRPHGNENSRFIYALNDISQVKNYKQDIKIHLKIDTGMHRNGICVENLEHAIDLIRSSNLKLTGMFTHFASADEMDGSFFVQKENFQKAKKMVKKYFSNLLFHSHNSAALFRGKIPEDEYCRIGLVQFGYGDSNLKRILSLYAHRLSQRILQKGQSIGYGGIFTAVKDMEVATYDLGYADGLFRYNGKGELVLGNGKAMLGKMSMDSFSCENSGEEICVFKDADIWADFFHTINYEILVKLNPNIQRVLV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: CISY_ASPNG
Sequence: MASTLRLGTSALRSSSIAAKPVVQSAAFNGLRCYSTGKAKSLKETFAEKLPAELEKVKKLRKEHGSKVIGEVTLDQAYGGARGVKCLVWEGSVLDSEEGIRFRGRTIPECQELLPKAPGGQEPLPEGLFWLLLTGEIPTEQQVRDLSAEWAARSDLPKFIEELIDRCPSTLHPMSQFSLAVTALEHESAFAKAYAKGINKKDYWNYTFEDSMDLIAKLPTIAAKIYRNVFKDGKVAPIQKDKDYSYNLANQLGYGDNNDFVELMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPMLSLAAGLNGLAGPLHGLANQEVLNWLTKMKAAIGNDLSDEAIKNYLWSTLNAGQVVPGYGHAVLRKTDPRYVSQREFALRKLPDDPMFKLVSQVYKIAPGVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRALGVLPQLIIDRALGAPIERPKSYSTELSPSLLVLSCK
What are the official names of this protein?
Citrate synthase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TRMD_STAES
Sequence: MKIDYLTLFPEMFEGVLNHSILKRAQDKGIINVNTINFRDYSINKHNQVDDYPFGGGQGMVLKPEPVFNAMEDINHNEHTRVILMCPQGRPFTQEIAQELSEAKHIVFICGHYEGYDERIRKHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNQASHQDDSFSDGLLEFPQYTRPREYKNMSVPEVLLSGNHAHIDQWRHEQKLIRTYEKRPDLLEQYPLTEKDREILETYKKKLKND
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_MYCBT
Sequence: MSKTSKAYRAAAAKVDRTNLYTPLQAAKLAKETSSTKQDATVEVAIRLGVDPRKADQMVRGTVNLPHGTGKTARVAVFAVGEKADAAVAAGADVVGSDDLIERIQGGWLEFDAAIAAPDQMAKVGRIARVLGPRGLMPNPKTGTVTADVAKAVADIKGGKINFRVDKQANLHFVIGKASFDEKLLAENYGAAIDEVLRLKPSSSKGRYLKKITVSTTTGPGIPVDPSITRNFAGE
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: FBW15_MOUSE
Sequence: MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS
What is the function of this protein?
Substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Promotes KAT7 ubiquitination and subsequent degradation in collaboration with MAP2K1 kinase, leading to reduced histone H3K14 acetylation and increased cell proliferation.
What are the official names of this protein?
F-box/WD repeat-containing protein 15.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum. Nucleus.
Protein: DISC1_MOUSE
Sequence: MQGGGPRGAPIHSPSHGADSGHGLPPAVAPQRRRLTRRPGYMRSTAGSGIGFLSPAVGMPHPSSAGLTGQQSQHSQSKAGQCGLDPGSHCQASLVGKPFLKSSLVPAVASEGHLHPAQRSMRKRPVHFAVHSKNDSRQSERLTGSFKPGDSGFWQELLSSDSFKSLAPSLDAPWNKGSRGLKTVKPLASPALNGPADIASLPGFQDTFTSSFSFIQLSLGAAGERGEAEGCLPSREAEPLHQRPQEMAAEASSSDRPHGDPRHLWTFSLHAAPGLADLAQVTRSSSRQSECGTVSSSSSDTGFSSQDASSAGGRGDQGGGWADAHGWHTLLREWEPMLQDYLLSNRRQLEVTSLILKLQKCQEKVVEDGDYDTAETLRQRLEELEQEKGRLSWALPSQQPALRSFLGYLAAQIQVALHGATQRAGSDDPEAPLEGQLRTTAQDSLPASITRRDWLIREKQRLQKEIEALQARMSALEAKEKRLSQELEEQEVLLRWPGCDLMALVAQMSPGQLQEVSKALGETLTSANQAPFQVEPPETLRSLRERTKSLNLAVRELTAQVCSGEKLCSSLRRRLSDLDTRLPALLEAKMLALSGSCFSTAKELTEEIWALSSEREGLEMFLGRLLALSSRNSRRLGIVKEDHLRCRQDLALQDAAHKTRMKANTVKCMEVLEGQLSSCRCPLLGRVWKADLETCQLLMQSLQLQEAGSSPHAEDEEQVHSTGEAAQTAALAVPRTPHPEEEKSPLQVLQEWDTHSALSPHCAAGPWKEDSHIVSAEVGEKCEAIGVKLLHLEDQLLGAMYSHDEALFQSLQGELQTVKETLQAMILQLQPTKEAGEASASYPTAGAQETEA
What is the function of this protein?
Involved in the regulation of multiple aspects of embryonic and adult neurogenesis (PubMed:17825401, PubMed:19502360, PubMed:31444471).  Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus (PubMed:17825401, PubMed:19502360).  Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance (PubMed:19303846).  Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation (PubMed:19778506).  Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A (PubMed:19778506).  Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development (PubMed:19502360).  Inhibits ATF4 transcription factor activity in neurons by disrupting ATF4 dimerization and DNA-binding (PubMed:31444471).  Plays a role, together with PCNT, in the microtubule network formation (By similarity).
What are the official names of this protein?
Disrupted in schizophrenia 1 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Mitochondrion. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Postsynaptic density. Note=Colocalizes with NDEL1 in the perinuclear region and the centrosome (PubMed:14962739). Localizes to punctate cytoplasmic foci which overlap in part with mitochondria. Colocalizes with PCNT at the centrosome (By similarity).
Protein: CCN3_COTJA
Sequence: MEPGGGHSLPVLLLLLLLLLLRPSEVNGREAPCPRPCGGRCPAEPPRCAPGVPAVLDGCGCCLVCARQRGESCSPLLPCDESGGLYCDRGPEDGGGTGICMVLEGDNCVFDGMIYRNGETFQPSCKYQCTCRDGQIGCLPRCNLGLLLPGPDCPFPRKIEVPGECCEKWVCEPRDEVLLGGFAMAAYRQEATLGIDVSDSSANCIEQTTEWSACSRSCGMGFSTRVTNRNQQCEMVKQTRLCMMRPCENEEPSDKKGKKCIRTKKSMKAVRFEYKNCTSVQTYKPRYCGLCNDGRCCTPHNTKTIQVEFRCPQGKFLKKPMMLINTCVCHGNCPQSNNAFFQPLDPMSSEAKI
What is the function of this protein?
Immediate-early protein likely to play a role in cell growth regulation.
What are the official names of this protein?
CCN family member 3, Cellular communication network factor 3, Nephroblastoma-overexpressed gene protein, Protein NOV.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cell junction, gap junction.
Protein: CE087_XENLA
Sequence: MATKSCPQCDQQVPVACKSCPCGYIFISRKLLHAKQSQRLPPTSENRSDPKRRRTERIKRERIHTAVNRDLENRKRSRSNSQSEASRRGRGRPKTATTKKHEEEKEKQEKEVDMYANLSDEKAFVFSVALAEINRKIINQRLIL
What are the official names of this protein?
UPF0547 protein C16orf87 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0547 family.
Protein: ADDB_EXIS2
Sequence: MNYMHLGRAGTGKTTQLIERVIDQLTEQPLGPSIYFIVPDQMSFEMERRIATDPRLSGLVRMEVMSLRRFAFHMIRDYGNQVIPFLDETGTQLLLRQVVEEAEEELKIFKRTKNMPGFYKGLDELIASFKRSLVNPDMLRQISGASPERSPKLNDLALIYERFTERISDKALHADDYFTTLIELLPKADLSDVSVFVDGFYEFSLQEQQVLLRLMELTKDMHLSFTLDVEDVYTKQSEFGVSQRCYMQLIEQMKERQIAHEDIYYGQTVKFQSTGLRMLEQALLSPGYPPTDEEVTGVTVSAAVNRQVETEAAVRKAIQLVRHDGYRFKDIAFLVRHLEPYADHLERAFQLYDIPYFLDQRESMVHHPIVELVHAVLEIVMTGYREESVFRLLKTELIPLPAEDPRLALDRLETFVLERGIKGSMWKKPWQLKRRLADEISLTDAELQEELELNEWRQFLVEAIEPLEKRFKASKTMSEYTRALYRFLEEHHMTDRLTVWKQQALEVNELSQAREHDQVYEAVLLLFEQLEAAAPEATLTTELFVQMVETGLESLRFSLVPPSLDQVIATDYVRGRLQQVKVVFLLGANDGLIPLVEDQSKLLSEGDHDFLHDQGIPVGKASLDVFDDELYYLYQGVTAPSESLHISYALVDEDGKALQPASIVKQIKHQLLQDRPVKTYFAEAGDHAPDDQLQFVTSPERAAAAAAIELRRLQRRYPIQPSWFDVYNRLLENGRGRERMALFSNALFYQNQAEPLPEDLARNLYGDTIKASVSRFETYNACSYKHFARYGLRLKERKLYKFEAPDIGNLFHGALNDLSMNIKASGKRWRELDDQSCSNLAKEAVEKVTPEIQNAILMSSNRFGYIKKKLTDVVEQTAKMLVKQAERSEFEPDLFEISFGNAMFPPLRFTLPDGTEIEFTGRIDRVDQATIGDQLYVRIVDYKSSAKELDFAEIYYGLAIQMLLYLKTVVEQSEVLFNQQAKPAGALYFHVKNPMMRGDLSADEIERNQLLLESYQMQGVIVENDEVLRAMDQIAYDERKKSPLVKVTFTKTGLHKSHTKGVVKEEELTALMDHAWDELKTSSQSMYAGDIAIDPFDYQERTPCTFCEYRSVCQFDQSLGNDYRQLNPLSEKEVLERLKEETE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: SRR1_LODEL
Sequence: MTRLTRPMVRSPISLPSTPSQLLHSASLSSSPSSPSLVQQSHSYHGDYFSIKPKLSLDFAHSSDNFSDESELENNSTSFVDDDDIVKVRETFDNISIDIGASNPFAKNKHQWSYSPITPYDIVDENHTITVSTPKTNSQLLYTTTSPQLPRKETLSLKFGPSTLKSTVSTSTSTSTSTSTGTNTETKTVTTAAKSTNFTLSMPNLQQHKFLLVDDNLINLKILNRILLKLYPKAQITQVLDSTKVAKLVEENEYDAVFIDIEMPVVNGVQIAQFIRSDVSKDDLTVIAVTTRNSKEDLALFEKTGIDYTFGKPLNYKLDFMANVIDEIIERRKGQMIKKSVSSVESGVSLCSKESTNTLLIA
What is the function of this protein?
Required for stress adaptation, morphogenesis and virulence.
What are the official names of this protein?
Stress response regulator protein 1.
Protein: NUOA_SALAR
Sequence: MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CNIH3_MOUSE
Sequence: MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization (By similarity).
What are the official names of this protein?
Protein cornichon homolog 3, CNIH-3, Cornichon family AMPA receptor auxiliary protein 3.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells).
Protein: CHERP_MOUSE
Sequence: MEMPMPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQAPELEPTSAMPPLPQPPLAPTASLTPAQGTPSMDELIQQSQWSLQQQEQHLLALRQEQVTTAVAHAVEQQMQKLLEETQLDMSEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQSLKTQHEEFVSSLAQQQQQQQQQQQQQPQPQPQPQIQLPQMEADVKATPPPPAPPPASAPAPTIPPTTQPDDNKPPIQMPGSSEYDTSAGVQDPAAAGPRGPGPHEQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDPNWNNQFEGPWNNQHEPPPWGGAQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPADMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSSSRSSKSSRSSSRSHSRSRSRSSSRSRSRSRSRSRSSRSRSRSRSRSRSKSYSPGRRRRSRSRSPTPPSAAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDEFSTFGTRKEEKED
What is the function of this protein?
Involved in calcium homeostasis, growth and proliferation.
What are the official names of this protein?
Calcium homeostasis endoplasmic reticulum protein, SR-related CTD-associated factor 6.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Distributed throughout the cytoplasm and also localizes to the perinuclear region. Colocalizes with ITPR1 (By similarity).
Protein: RNPH_PSYA2
Sequence: MRIDNRELNQLRSISFERHYTKHAEGSVLVSFGDTKVLCTASVESGVPRWLKGKGKGWITAEYGMLPRATNTRNQREAARGKQSGRTQEIQRLIGRSLRAMIDLSKLGENTIYLDCDVLQADGGTRTASVTGAAIALIDALESIQKTKKLKADPLIGLVAAVSVGMKDGEAYLDLNYEEDASCDTDLNVVMTQKGEFIELQGTAEEKPFTRAQADDMLVLAEKGIAELIAMQKTALGW
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: EFG_XYLFA
Sequence: MVRATPIHRYRNIGIMAHIDAGKTTTSERILFYAGVCHQMGEVHDGAAVMDWMEQEQERGITITSAATTVFWSGMDKSMPQHRFNIIDTPGHVDFTIEVERSLRVLDGAVFVLCAVGGVQPQSETVWRQANKYFVPRMAFVNKMDRTGANFDKVVEQLKARLGAYPVPMQVPIGAEDGFEGVIDLLKMKAIHWDAASQGTVFEYRDIPIELVDKASKARAFMVEAAAEATEELMDKYLNEGELKEQEILQGLRERTLKVEIIPVFCGSAFKNKGVQAMLDGVIHLLPSPADRPPVQGLDEKGNECRCKASDSEPFSALAFKIMTDPFVGSLTFFRVYSGVLNSGDQVYNSVKLKKERVGRILQMHSNQRDEIKEVRAGDIAAAVGLKDVTTGDTLCDQNHIITLERMIFPEPVISMAVEPKTKSDQEKMGMALGRLAQEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFNVEANVGKPQVAYRETIRKSDVKSDYKHVKQSGGKGQYGHVVIEISPMSDVDKQHPDVKGDFLFINEITGGVIPKEFISPIEKGLRETITSGPLAGFPVVGVKVKLVFGSYHDVDSSEMAFKLAASMAFKQGFAKANPVLLEPIMKVEIVSPEDYLGDIMGDVSRRRGVLQGQDDSLSGKVINAMIPLGEMFGYATSLRSMTQGRATFAMEFDHYEEAPANIADTVIKKT
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKM8_SCHPO
Sequence: MVSNNAVIIKKYLDSTAGYPVIGEHLAFEKREFDLENAQVDEETPVLLKNIYTSVDPYLRMRMQSPKHASYIPPLELGKPFYNSTVAKVVKSTLDQYKPGMDVVFVSGWEEYTFVSKQALGFLQPINNPYKLPLIDFVGSLGMPSQTAYCGLKHIGKPKAGETIYISAASGAVGQMAGQLAKAMGLHVVGSVGSDEKFKICLDSGYDSVFNYKKESPFKALPRLCPKGIDIYFENVGGETMDAVLENMNLQGRIIFCGAISQYNNPNPYRVKNLGMVLVKSLTIQGFIVANILPQYQEQYFEEMPKLIAEGKIKYKCDVYDGLESAPEAFIGMLQGKNSGKTIVKIADE
What are the official names of this protein?
Zinc-type alcohol dehydrogenase-like protein PB24D3.08c.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TAT_HV1S1
Sequence: MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKGLGISYGRKKRRQRRRAPPDSEVHQVSLPKQPASQPQGDPTGPKESKKKVERETETDPVH
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: RNH_PSEF5
Sequence: MSDSVEIFTDGACKGNPGPGGWGALLVCKGVEKELWGGEANTTNNRMELMAAIRGLEELKRQCDVQLVTDSQYVMKGINEWMANWKKRGWKTAAKEPVKNADLWQQLDEQVNRHNVTWKWVRGHTGHHGNERADQLANRGVDEVRGYKQP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_STRPB
Sequence: MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDADEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAFHDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL81_ARATH
Sequence: MGRVIRAQRKGAGSVFKSHTHHRKGPAKFRSLDFGERNGYLKGVVTEIIHDPGRGAPLARVTFRHPFRFKKQKELFVAAEGMYTGQFLYCGKKATLVVGNVLPLRSIPEGAVVCNVEHHVGDRGVLARASGDYAIVIAHNPDSDTTRIKLPSGSKKIVPSGCRAMIGQVAGGGRTEKPMLKAGNAYHKYRVKRNSWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDAPPGQKVGLIAARRTGRLRGQAAASAAKAD
What are the official names of this protein?
60S ribosomal protein L8-1, 60S ribosomal protein L2, Protein EMBRYO DEFECTIVE 2296.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRIX_METAC
Sequence: MLITTSRKPSAKTRTLCKLLSRFITGRCITRGKMGMQELIGFAEGGPLIVVGEYHGNPGELGFYDDAGKLLFSLRFSDWYSEDIGSYWFPDLEPVLAGQGEIADAFESFFHFKRVESEEVDQLPPLSTVLVAGEKEIDFTGSGKSLFKLNVKGFKKY
What is the function of this protein?
Probably involved in the biogenesis of the ribosome.
What are the official names of this protein?
Probable Brix domain-containing ribosomal biogenesis protein.
Protein: RPFB_MYCTO
Sequence: MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMRVTTMKSRVIDIVEENGFSVDDRDDLYPAAGVQVHDADTIVLRRSRPLQISLDGHDAKQVWTTASTVDEALAQLAMTDTAPAAASRASRVPLSGMALPVVSAKTVQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAATAPIVEGMQIQVTRNRIKKVTERLPLPPNARRVEDPEMNMSREVVEDPGVPGTQDVTFAVAEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVIDGSIWDAIAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQIAVAEVTRLRQGWGAWPVCAARAGAR
What is the function of this protein?
Factor that stimulates resuscitation of dormant cells.  Has peptidoglycan (PG) hydrolytic activity.  PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity).
What are the official names of this protein?
Resuscitation-promoting factor RpfB.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. Rpf subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYC_ALKMQ
Sequence: MRLYNTLTRKKEVFVPIEQGKVRMYACGPTVYNYFHIGNGRTFIVFDALRKYLVYRGYDVTFVQNFTDIDDKIIKKAQEEAVSAKEISERFIVEYFKDAATLGVDQADIHPKVTENVPEIIAFIQELLEKNVAYEVNGDVYYDVSRFEDYGKLSKQNLEELQSGARIEVNEAKRNSLDFVLWKTAKPGEPSWESPWGSGRPGWHIECSAMAKKYLGETIDIHGGGGDLVFPHHENEIAQSEACTGKTFANYWIHVGYLNIDNKKMSKSLDNFFTPREIAEEYDLESLRFFMLSAHYRTPVNFSRELLESAKSGLERLYNAKNHLEHILENTKVEEMKETEKEWIDSLTHYSEEFNRVMDDDFNTADGIAVIFDLVRDMNTYITGEASKEAVKAAYGMLVELTGVLGLLRKEEESLDKEIGRLIEARQQARIEKNFTKSDEIRDYLKEKGIVLEDTSQGVKWRKE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_BACP3
Sequence: MKTIHVSVVTPDGPVYEDDVEMVSVKAKSGELGILPGHIPLVAPLEISAARLKKGGKTQYIAVSGGFLEVRPDNVTILAQAAERAEDIDVLRAKARKSGRTPLQSQQDDIDFKRAELALKRAMNRLSVAEMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.