PharMolix/UniProtQA huggingface dataset:
Protein: KAD_RICBR
Sequence: MIIIFLGPPGAGKGTQGKKIAKKIHLPHIAIGDIFRAIIKTSSKDAEVINSYVEQGKLIPDEIVNHIIKNFLSSSDYKKGYILDGYPRNLEQAKFFESFVTEKIKVIYLNVSDELLIKRILGRYSCKSCGKIYNDYFLKPRIDKICDVCKSSVFEYRKDDNEEVIKERINIFKTETYPLIQHYKNNDDFYMIDGNKNEEQIEDHIEKVLKIN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YD1V_SCHPO
Sequence: MSLKMFVNEKFIEDWCRETGEQVDHQLVCTVGEKSKEKICLLERTCSLEGLSTVLMSENFKDTLEEELKDCDSHLDRAANDSPSLSCILGNAND
What are the official names of this protein?
Uncharacterized protein C4G9.22.
Protein: Y2421_YERE8
Sequence: MYPVDLHMHTIASTHAYSTLHDYIAEAKLKNIKLFAITDHGPDMADAPHYWHFMNMRVWPRLVDGVGILRGIEANIKNLDGDIDCTGPMLDAIDLLIAGFHEPVFPPQDKAANTQAMIATMAQGNVHIISHPGNPKYPVDIKAIAEAAAKYNVALELNNSSFTHSRKGSETNCRAIAEAVRDAGGWLALGSDSHIAYSLGIFEHCERIIAEVNFPQERILNVSPRRLLNFLEQRGRAPIPELAGL
What are the official names of this protein?
Probable phosphatase YE2421.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: IME4_YEAST
Sequence: MINDKLVHFLIQNYDDILRAPLSGQLKDVYSLYISGGYDDEMQKLRNDKDEVLQFEQFWNDLQDIIFATPQSIQFDQNLLVADRPEKIVYLDVFSLKILYNKFHAFYYTLKSSSSSCEEKVSSLTTKPEADSEKDQLLGRLLGVLNWDVNVSNQGLPREQLSNRLQNLLREKPSSFQLAKERAKYTTEVIEYIPICSDYSHASLLSTSVYIVNNKIVSLQWSKISACQENHPGLIECIQSKIHFIPNIKPQTDISLGDCSYLDTCHKLNTCRYIHYLQYIPSCLQERADRETASENKRIRSNVSIPFYTLGNCSAHCIKKALPAQWIRCDVRKFDFRVLGKFSVVIADPAWNIHMNLPYGTCNDIELLGLPLHELQDEGIIFLWVTGRAIELGKESLNNWGYNVINEVSWIKTNQLGRTIVTGRTGHWLNHSKEHLLVGLKGNPKWINKHIDVDLIVSMTRETSRKPDELYGIAERLAGTHARKLEIFGRDHNTRPGWFTIGNQLTGNCIYEMDVERKYQEFMKSKTGTSHTGTKKIDKKQPSKLQQQHQQQYWNNMDMGSGKYYAEAKQNPMNQKHTPFESKQQQKQQFQTLNNLYFAQ
What is the function of this protein?
Catalytic component of the MIS complex, a complex that mediates N6-methyladenosine (m6A) methylation on some mRNAs during meiosis and is required for sporulation.  M6A, which takes place on the adenosine of 5'-[AG]GAC-3' consensus sites of some mRNAs, is probably required to initiate sporulation.  Positive regulator for IME2.
What are the official names of this protein?
N6-adenosine-methyltransferase IME4.
What is the protein family that this protein belongs to?
Belongs to the MT-A70-like family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Localizes in the nucleolus during the period of m6A mRNA accumulation.
Protein: RL7_LIBAS
Sequence: MSNIESIVEKLSSLTLIEAAELSKRLEKEWGVSASAPVSVVAPVAAEAGSAASEKTEFEVVLKGFDDPKKKIAVIKEVRAITDLGLKEAKELVESAPKSLKTGLSKDEANEMKKKLEDAGAT
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: URE3_STAES
Sequence: MHFTQREQDKLMIVVAAEVARRRKARGLKLNHPEALALISDELLEGARDGKTVAELMSYGKTILNEEDVMDGVANMITELEIEATFPDGTKLITVHHPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_FUSNN
Sequence: MSNHVIIKGKNDRLVIALDPNIDFLDICDILKTKILEAKDFIGNSRMAIEFSGRALTNEEENKLIGIITDNSDIVVSYIFSKRAESEEENIDLNSLNPLIEEGKTHFFRGTLRSGSKIESDGNVVVLGDVNPSSMIRARGNVIVLGHLNGTVCAGLGGDDRAFIAAIYFNPIQITIGMKTITDIQDEILDSTRVDKKSKFKVASIKNQEIVVEELI
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization (By similarity).
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: Y802_HAEDU
Sequence: MALWKRLTNRTNRSQGACFEQKARLFLEQQGLKFIQANQHFKCGELDLVMQQGDTIVFVEVRQRKNNRFGSALESIDYRKQQKWLDAANMWLLTEYNQSLDTANCRFDVVAFEAEQPPLWIQNFLG
What are the official names of this protein?
UPF0102 protein HD_0802.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: KEFF_ECOL5
Sequence: MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGTHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COX2_LEITA
Sequence: MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YIDC_XANC8
Sequence: MNQTRVFLIFAWLMVAALLWMEWGKDKAPANAPTPIASQAVPAARDPDAAAPAANVPSAQAIPQAGSPAAVPATSTTTATPATTGAAPAITLTSDVLRLKLDGRSVLDAELLQFPQTKDGTEPVKLLTEDAAHPYNATSGWASERSPVPGVGGFRAEQPGTTFELAKGQNTLVVPFVWNGPNGVSIRRIFTLQRGSYAISIKDEVINKSDAAWNGYVFRKLSRVPTILSRGMTNPDSFSFNGATWYSPQEGYERRAFKDYMDDGGLNRQITGGWVALLQHHFFTAWIPQKDQASLYVLAQDGPRDVAELRGPAFTVAPGQSASTEARLWVGPKLVSLLAKEDVKGLDRVVDYSRFSIMAIIGQGLFWVLSHLHSFLHNWGWAIIGLVVLLRLALYPLSAAQYKSGAKMRRFQPRLAQLKERYGDDRQKYQQATMELFKKEKINPMGGCLPLLIQMPIFFALYWVLVESVELRQAPWLGWIQDLTARDPYFILPVLNIAIMWATQKLTPTPGMDPMQAKMMQFMPLVFGVMMAFMPAGLVLYWVVNGGLGLLIQWWMIRQHGEKPSKIIQANAK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS28_PYRNV
Sequence: MAEEVKFSPYEDAVAGLVVQILGRTGVAGEVTQVKIKVLEGRDKGRVLTRNVKGPVRLGDIVMLRETEREARRITAR
What are the official names of this protein?
30S ribosomal protein S28e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: RIR2H_MYCSK
Sequence: MTRTRSDSLAAGGLNWNSMPLKLFAGGNAKFWDPADIDFSRDRADWESLSNLERDWATRLCAQFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGMTDDLQCYLDDLPSYRQMFYEELPASLEALATDPSPAAQVRASATYNHVIEGMMALTGYYAWHRICVDRKVLPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWEVFENRMNELIPLALSNTDDSFALYDEIPFGFAKEEFQQYAADKGMRRFGTISSARGRALAEIDVDYSPLQLEDTFAAEDSRVLATSA
What is the function of this protein?
Probable oxidase that might be involved in lipid metabolism.
What are the official names of this protein?
R2-like ligand binding oxidase, Ribonucleotide reductase R2 subunit homolog, Ribonucleotide reductase small subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
Protein: ASES_SARSR
Sequence: MRLSLVLALLPVAFGAPTRRDEPAPLHVPRDVDSLIKDTYIVKYKDITAFSAVDEGLKLLSGKPKHIYKGAFKGFSGKIDAKTLELLRDDPSVDFIEQDAIVTLAAYTTQASAPWGLARISTRQRGPTGYTYDDSAGAGTCSYIIDTGIQANHPNFGGRAFQLVSYQGSNADGNGHGTHVAGTIGSTTYGVAKRTTLLGVKVLSDSGSGSTSGIIAGINYVVSDSRSRSCPNGSVANMSLGGGYSASLNSAAKSLIDNNIFLAVAAGNENQNAANVSPASEPTVCTVGATTSADAKASFSNYGSGVDIFAPGQSILSTWIGSSTNTISGTSMASPHIAGLAAYLAGLEGFPGAQALCNRIVALATTGVITGLPSGTPNRLAFNGNPSG
What is the function of this protein?
Extracellular elicitor protein that induces a strong defense response in strawberry and confers both local and systemic plant resistance against the fungal pathogen Colletotricum acutatum, the casual agent of anthracnose disease (PubMed:23530047).  AsES activates a cascade of defense responses, including calcium influx, oxidative burst, hypersensitive cell-death response (HR), accumulation of autofluorescent compounds, cell-wall reinforcement with callose and lignin deposition, salicylic acid accumulation, and expression of defense-related genes, such as PR1, PG1, MYB30, RBOH-D, RBOH-F, CHI23, and FLS (PubMed:23530047, PubMed:26706064, PubMed:28635519).  The oxidative burst consists in a progressive extracellular accumulation of H(2)O(2) that starts immediately after the contact with AsES and is preceded by a rapid and transient cell membrane depolarization.  During this phase takes place also a rapid intracellular accumulation of NO at the chloroplasts.  After the first extracellular H(2)O(2) production phase, two intracellular H(2)O(2) accumulation events occur, the first 2 hours after induction, and the second 7 hours after induction.  AsES also produces a transient increase of ion leakage, and a progressive alkalinization of the extracellular medium (PubMed:26562675).  Confers also local and systemic plant resistance against Botrytis cinerea in Arabidopsis thaliana.  Systemic, but not local resistance is dependent on the length of exposure to AsES.  The protection to B. cinerea is due to the induction of the plant defenses via the salicylic acid, jasmonic acid and ethylene signaling pathways (PubMed:26706064).  Exhibits subtilisin-like proteolytic activity which is necessary but not sufficient for its elicitor function in strawberry plants.  Probably induces defense by means of proteolysis of one or multiple host proteins that are specific targets of this protease (PubMed:23530047).
What are the official names of this protein?
Subtilisin-like serine protease AsES, Alkaline serine protease AsES, Extra-cellular elicitor protein AsES.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MINC_SYNY3
Sequence: MSDDTPHPEWQLVPQGNFVRLSLTLPTVTTAPDSPSLVFSHQQLEQSLGNYLRIMAGRWQDQTLVRLAVNNQLLDARQLQAIAAGLKEQNLTLQWVETNRRQTAVAAASAGLSVDQTMADKPLVDPSETPSLPKPLVVRHTLRSGGEIRHGGDVVIIGDVNPGSSIVADGDILIWGCLRGMAHAGAKGNDQAVIMILRLAACQIRIGDRLARVGADAVDRREPEIAYITSEGIRLTPVRQFQRSALL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization (By similarity).
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: CCR5_CERGA
Sequence: MDYQVSSPTYDIDYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLLFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEASERASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDUI1_ENTFA
Sequence: METRYTHSPADIRHYSTEQLRDEFLVEKVFIPGAISLTYTHNDRMIFGGVTPTTEELEIILDKELGVDYFLERRELGVINIGGPGFIEIDGAKETMKKQDGYYIGKETKHVRFSSENPDNPAKFYISCVPAHHKYPNVKISIDEITPMETGDPLTLNQRKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDMEEDTRIFHMMGKPDETKHLVMSNEQAAISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVAMDQLK
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 1, 5-keto-4-deoxyuronate isomerase 1, DKI isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: ACRO_RABIT
Sequence: MLPTAVLLVLVVSVVAKDNATCDGPCGLRFRQNPQGGFRVVGGQAAQQGAWPWMVSLQIFTPRNNRRYHACGGVLLNAHWVLTAAHCFNNKQKVYEWRMVFGAQEIEYGTDKPVRPPLQERYVEKVVTHDQYNYMTEGNDIALLKITPPVPCGPFIGPGCLPNSKAGPPKAAQTCYVAGWGYVKENAPRPSPTLMEARVDLINLELCNSTQWYNGRITASNLCAGYPSGKIDTCQGDSGGPLMCRENQGEPFVVQGITSWGVGCARAKRPGIYTATWPFLDWIASRIGSNALRMIQPATPTPPTTRSPGVHQPPSAHPPWYFQHASGPPHPHPHPHPHPHPRPPQPPAAQAPPPPPPPPPPPPPPPPPPPPPPPPPPPASTKPPQALSFAKRLQQLVEVLKGGSTFSGAKRVDTAAAAAEATEIPEVTLAS
What is the function of this protein?
Acrosin is the major protease of mammalian spermatozoa.  It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
What are the official names of this protein?
Acrosin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: RRF_NOCSJ
Sequence: MINDILNEADGKMDKSVEATREEFAAIRAGRVNPSMFNKIVVDYYGSPTPLQQLASFTAPEARIILIAPYDQGAMHNILKAIRDSDLGVNPADDGKVIRCVFPELTEERRKEYIKISRHKAEEGRVAVRNLRRTAKQHLERLEKDGEVGQDDLTGAEKRLDGLTKKHTDAIDEMLKHKEAELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_RICFE
Sequence: MTKNIGKITQIISAVVDVKFTNNGELPEILNALECYNDKQRIVLEVAQHIGDDTVRCIAMDSTEGLVRGVEVIDTGSPIRIPVGTETLGRIMNVVGEPIDGKGDIKSSNISSIYKSAPDFTNQSTERNILVTGIKVVDLLAPYTKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYTVFAGVGERTREGNDLYHEMIDSGVIDLEKPENSKVALVYGQMNEPPGARARVALSGLTIAESFRDMNEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGELQERITSTKNGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRQIAELGIYPAVDPLDSNSQVLDPMIVGEEHYSVARQVQQILQTYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFHVAEVFTGAEGKFVNLADTIAGFKGLVEGKYDDLPEAAFYMVGTMDEAIEKAKILKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NU4LM_HORSE
Sequence: MSLVHINIFLAFTVSLVGLLMYRSHLMSSLLCLEGMMLSLFVMATMMVLNTHFTLASMMPIILLVFAACERALGLSLLVMVSNTYGVDHVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NP1L6_HUMAN
Sequence: MMEGLGEHSTAGEMGPLLGAVAATASPQSLMEYSSDADFIESLPLVVKYRVYTLKKLQAKCAVLEAKYLREFHSVERKFATIYGPLLEKRRQITNALYEPTKEECER
What are the official names of this protein?
Putative nucleosome assembly protein 1-like 6.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
Protein: HTPG_RHOJR
Sequence: MSTKIEQLEFQAETRQLLDLMIHSVYSNKDSFLRELISNASDALDKLRLEAFRNKELHVDTSDLHVEIEVDAEKRTLTVRDNGIGMSHDEVVDLIGTLAKSGTADLRRKLKEAKDAAASEELIGQFGIGFYSTFMVADKVTLLTRKAGESEATRWESSGEATYTIEAVDDAPQGSSVTLHLKPEDAEDHLHDYTSERKIKELVKRYSDFIAWPIRMNVERTVPAEGDGEDEVTTTSETINSMKALWARSKDDVSEDEYKEFYKHIAHAWDDPLEVIPMKAEGTFEFQALLFIPSHAPFDLFMRDGKTGVQLYVKRVFIMDDCDQLMPEYLRFVKGVVDAQDLSLNVSREILQQDRQIRAIRRRLTKKVLTTIKDLKTERPDDYRTFWAEFGRAVKEGLMSDTDNRDVLLGISSFASTHSEEELTSLEDYVARMKDGQEQIFYATGESRQLLESSPHMEAFRAKGFEVLLLTDPVDEMWVGAVPEFDGKSFQSIAKGEVDLDTEEDKKAHESEREEQEKDFAGLLSWMADALSEQVKEVRLSTRLTTSPACIVGDAFSMSPALERMYRASGQPVPVTKRILELNPTHPLVTGLREAHGERNEDPALGETAELLYGMALLAEGGELEDPARFTTMLANRLARTV
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOC1_MESAU
Sequence: MRLLISLPVLIVVLAMALEGPAPAQATPDLSSAFENLPEKLKEFGNTLEDKARAAIEHIKQKEILTKTRTWFSETFGKLKEKLKTTFD
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein (By similarity).  Binds free fatty acids and reduces their intracellular esterification (By similarity).
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PBP_ANTPO
Sequence: MLRKISLLLLPVFVAINLVHSSPEIMKNLSNNFGKAMDQCKDELSLPDSVVADLYNFWKDDYVMTDRLAGCAINCLATKLDVVDPDGNLHHGNAKDFAMKHGADETMAQQLVDIIHGCEKSAPPNDDKCMKTIDVAMCFKKEIHKLNWVPNMDLVIGEVLAEV
What is the function of this protein?
This major soluble protein in olfactory sensilla of male moths might serve to solubilize the extremely hydrophobic pheromone molecules and to transport pheromone through the aqueous lymph to receptors located on olfactory cilia.
What are the official names of this protein?
Pheromone-binding protein, PBP.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
Protein: 6PGD_BACLI
Sequence: MRNTIGVIGLGVMGSNIALNMASKGEQVAVYNYTRDLTDQLVQKTGGQTVKPYYELEDFVQSLEKPRKIFLMVTAGKPVDSVIDSLVPLLEEGDVIMDGGNSHYEDTERRYDSLKAKGIGYLGIGISGGEVGALKGPSIMPGGDRDVYEKAAPILTKIAAQVEGDPCCVYIGPKGAGHFVKMVHNGIEYADMQLIAEAYTFLREKLLLPIDEIADIFDTWNQGELKSYLIEITAEILRKKDERTGAPLIDVILDKTGQKGTGKWTSLQAIDNGIPSSIITESLFARYLSSLKDERTAAENVLAGPETEERPLDQNVWIDRVRQALYMGKVCAYAQGFAQYKMTSDLNGWHLPLKDIALIFRGGCIIRAQFLNLISEVYDKQPDLSNLLVAPDFAEKLKEYQSGLRKVVCEGISSGISFPCLSTALSYYDGYRTGRSNANLLQAQANYFGAHTYERTDMEGVFHTDWY
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: CCD71_ORYSJ
Sequence: MDDDDDTSFNNSLDLYCDEDPFDSTPPPPPPPPEQQQQAGTTTPDDIDDEVMEYYKAKQRCYALQIRDYCCYLQCHHLLLQQQQHGVAAARLKAAMGRLGLEAATAFNAANYLDRFLSINCHLKWEEWMVEVVSVGCLSLACKLDEVTIPSLHDLQMEEAMGHSFRASTIRDMELTLLKALRWRLACVTPFSFLPVTTTTTTTRALLLRSLLDPSFLRFDASLLAASALTLSSTTPQHPNHLLLNRLIHPFSQTDHEVKECFNMMKALHLDMSKNPGRSSDHPCWSPISVVIPFHTDGTVKRSAISRCLFGSGRLKARSI
What are the official names of this protein?
Putative cyclin-D7-1, G1/S-specific cyclin-D7-1, CycD7;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: IL12B_CANLF
Sequence: MHPQQLVISWFSLVLLASSLMTIWELEKDVYVVELDWHPDAPGEMVVLTCHTPEEDDITWTSAQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGKVLSRSLLLIHKKEDGIWSTDILKEQKESKNKIFLKCEAKNYSGRFTCWWLTAISTDLKFSVKSSRGFSDPQGVTCGAVTLSAERVRVDNRDYKKYTVECQEGSACPSAEESLPIEVVVDAIHKLKYENYTSSFFIRDIIKPDPPTNLQLKPLKNSRHVEVSWEYPDTWSTPHSYFSLTFCVQAQGKNNREKKDRLCVDKTSAKVVCHKDAKIRVQARDRYYSSSWSDWASVSCS
What is the function of this protein?
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity.  IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues.  IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines.  IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity).
What are the official names of this protein?
Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40.
What is the protein family that this protein belongs to?
Belongs to the IL-12B family.
What are the subcellular locations of this protein?
Secreted.