PharMolix/UniProtQA huggingface dataset:
Protein: FSA2_FUSSF
Sequence: MSNVTVSAFTVDKSISEEHVLPSSFIPGSGNIFPKFTSAIPKTAWELWYFDGISKDDKSSIVIGVTRNAEGLKHGGFKVQVFVIWADERTWHRDLFFPESVVSINESGVTDGIWKDATSNSSISFSCAGDLSKASLVFDVPGVVQGDMHLEALPGDTGLDTDARLGPSVYYVRPIGRASVKAQLSLYSSDATAAEQFSLGTSANGGMDRVWSPLSWPQVMTESYYLRTQVGPYAMQIMRIFPPAGSEDQPSTMARLYREGQLVCVAQHVVTREDALMTHDSLILSKQDNSDSEDVVTGGYRDKNTGYTVEFVEKGNEGQRWKFQVRHERIIWNTPTSRPGPDATGNTGFVEVLCGGTIGESYEGVGTGGQCELS
What is the function of this protein?
Diels-Alderase; part of the gene cluster that mediates the biosynthesis of the HIV-1 integrase inhibitor equisetin and of fusarisetin A, both trans-fused decalin-containing tetramic acids showing also antimicrobial activity (PubMed:25770422).  The PKS module of fsa1 together with the enoylreductase fsa3 catalyze the formation of the polyketide unit which is then conjugated to L-serine by the condensation domain of the fsa1 NRPS module (PubMed:25770422).  Activity of the Dieckmann cyclase domain (RED) results in release of the Dieckmann product intermediate (PubMed:25770422).  Diels-Alderase fsa2 is involved in endo-selective Diels-Alder cycloaddition to form the decalin ring, leading to the production of N-desmethylequisetin also called trichosetin (PubMed:25770422, PubMed:28401214, PubMed:29972614, PubMed:34121297).  Subsequent N-methylation is carried out by fsa4 to give equisetin (PubMed:25770422).  The enzymatic gene responsible for the conversion of equisetin to fusarisetin A has not been identified yet and is probably located outside of the fsa cluster (PubMed:28401214).
What are the official names of this protein?
Diels-Alderase fsa2, Fusarisetin A biosynthesis protein 2.
What is the protein family that this protein belongs to?
Belongs to the Diels-Alderase family.
Protein: NSRR_SHIB3
Sequence: MQLTNFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: CBAL_GEOSE
Sequence: KAWFVLSMRAVGGLFVDLWTSVAKTVKGWL
What are the official names of this protein?
Alanine carboxypeptidase.
Protein: MURG_GEOMG
Sequence: MRLLIAGGGTGGHLFPGIAVAEEFLSRKKGNEVLFVGTWRGIEARVLPKLGYRLECITAAGIRGKGSVARAKGLAKFLYGYAQSRKILKEFKPDLVLGVGGYASAPALLAARGMHIPRFIHEQNAIPGFTNKMLATVAERVFISLEESRKFFPEERTLLTGNPLRRQILEQVALAPQEERTDDAFHLLVFGGSAGAHRINLIMGEVLPHLEDVKERLRITHQTGENDLEDVTSAYEEQGVAADVVAFIDSMADAYRWADLVVCRAGATTIAEITACGKPCIFIPYPHAVDDHQRRNAEALLKRGAGFVIIEQELSGEVLAKTIRDLMADPARLKSVGEAAQGLARLDAAQVIVDEMMTSKRKEK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2120_BACMK
Sequence: MKKTFYHYMMKHRAALFKNEISDLAEAMYDDLSFPKQSEDYDVISSYLELSGMLESMSIFDDAWDLYIQER
What are the official names of this protein?
UPF0346 protein BcerKBAB4_2120.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: Y91_SIRV1
Sequence: MTDYKNGIKKLLQKCFSDKSIDVIFMSCNNLSPHKDYMIIDPETKYYIGYILTNGIKIPFIAEVWHNNTTRIYLDPRKNFYLALFIGDLNV
What are the official names of this protein?
Uncharacterized protein 91.
Protein: GLNA_LACSA
Sequence: MALLSDLVNLDLSSITDKIIAEYIWIGGSGMDLRSKARTLSGPVSDPSELPKWNYDGSSTGQAPGEDSEVIIYPQAIFKDPFRRGNHILVMCDAYTPAGEPIPTNKRAAAAKIFSNPEVEKEVTWYGIEQEYTLLQKDTNWPLGWPLGGFPGPQGPYYCGIGADKAFGRDIVDAHYKACLYAGVNISGINGEVMPGQWEFQVGPSVGIAAADQIWVARYILERITEIYGVVVSFDPKPIPGDWNGAGAHTNYSTKTMREEGGYEVIKKAIEKLGLRHKEHIAAYGEGNERRLTGRHETADINTFLWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYVVTSMIAETTILWDNKS
What are the official names of this protein?
Glutamine synthetase, GS(1), Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3H1_CRORU
Sequence: LGTDIISPPVCGNELLEVGEECDCGFPRNCRDPCCDATTCKLHSWVECESGECCGQCKFTSAGNECRPARSECDIAESCTGQSADCPMDDFHRNGQPCLNNFGYCYNGNCPILYHQCYALFGSNVYEAEDSCFERNQKGDDDGYCRKENGEKIPCAPEDVKCGRLYCKDNSPGPNDSCKTFNSNEDDHKEMVLPGTKCADGKVCSNGHCVDVASAY
What is the function of this protein?
Zinc protease from snake venom that induces hemorrhage.
What are the official names of this protein?
Snake venom metalloproteinase HT-1, SVMP, Hemorrhagic metalloproteinase HT-1, Hemorrhagic toxin I.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL126_PLAVT
Sequence: MRYLLAVLIAAAFVISSGTSVSTIADDELILSKDTTIGAAVAPTFHDDKRMLQTKAVNGLEEERGWPLLETGIGKIKMGGKKFKHATKRMFGMVSPAGEAKFEAYKGLHKLKRGLIRMYRRVKWWFQKNILRQKHALEEGATRAKHKVSEANQKLKHRTKESEKTAYHRLKEAFQKFRHRMKDFFKKMRVYAY
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 126.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host membrane.
Protein: TRMN_THET2
Sequence: MWLEATTHPGLEDLLLEELSALYPGEGAEVDARKGRVRIPRAWVGEEALGLRLAHHLVLFRARLLLSREDPLGALERAALALPWPELEGAGSFRVEARREGEHPFTSPEVERRVGEALHRAYGVPVDLKRPAVRVRVDVRGEEAFLGVQLTERPLSRRFPKAALRGSLTPVLAQALLRLADARPGMRVLDPFTGSGTIALEAASTLGPTSPVYAGDLDEKRLGLAREAALASGLSWIRFLRADARHLPRFFPEVDRILANPPHGLRLGRKEGLFHLYWDFLRGALALLPPGGRVALLTLRPALLKRALPPGFALRHARVVEQGGVYPRVFVLEKL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the methylation of the guanosine nucleotide at position 6 (m2G6) in tRNA(Phe).
What are the official names of this protein?
tRNA (guanine(6)-N2)-methyltransferase, tRNA:m2G6 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WFKN2_MOUSE
Sequence: MCAPGYHRFWFHWGLLLLLLLEAPLRGLALPPIRYSHAGICPNDMNPNLWVDAQSTCKRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCFMDAEACSKGITLSVVTCRYHFTWPNTSPPPPETTVHPTTASPETLGLDMAAPALLNHPVHQSVTVGETVSFLCDVVGRPRPELTWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNVQPQDAGIYTCTARNVAGVLRADFPLSVVRGGQARATSESSLNGTAFPATECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHHNLNHFETYEACMLACMSGPLAICSLPALQGPCKAYVPRWAYNSQTGLCQSFVYGGCEGNGNNFESREACEESCPFPRGNQHCRACKPRQKLVTSFCRSDFVILGRVSELTEEQDSGRALVTVDEVLKDEKMGLKFLGREPLEVTLLHVDWTCPCPNVTVGETPLIIMGEVDGGMAMLRPDSFVGASSTRRVRKLREVMYKKTCDVLKDFLGLQ
What is the function of this protein?
Protease-inhibitor that contains multiple distinct protease inhibitor domains.  Probably has serine protease- and metalloprotease-inhibitor activity (By similarity).  Inhibits the biological activity of mature myostatin, but not activin.
What are the official names of this protein?
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2, Growth and differentiation factor-associated serum protein 1, GASP-1, mGASP-1.
What is the protein family that this protein belongs to?
Belongs to the WFIKKN family.
What are the subcellular locations of this protein?
Secreted.
Protein: SLA8_MACLB
Sequence: DCLPGWSSHEGHCYKVFNLAKTWEDAEKFCTEQANSGHLVSIDSKKEANFVAELVSQNIKETRRTDFVWIGLRVEDKRQHCSSEWSDGSSINYQNWIEAESKKCLGLEKQTRYRKWVNLNCGQPYRFTCEI
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec A8, C-type lectin A8.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14Z_FINM2
Sequence: MAKKSMIAKQKRPAKFSTREYNRCKICGRPHGYLKKYGICRICFRELAYKGEIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PP13G_HUMAN
Sequence: MEPIGARLSLEAPGPAPFREAPPAEELPAPVVPCVQGGGDGGGASETPSPDAQLGDRPLSPKEEAAPQEQEELLECRRRCRARSFSLPADPILQAAKFLQQQQQQAVALGGEGAEDAQLGPGGCCAKCKKRVQFADTLGLSLASVKHFSEAEEPQVPPAVLSRLRSFPMRAEDLEQLGGLLAAAAVAAPLSAPPSRLRPLFQLPGPSAAAERLQRQRVCLERVQCSTASGAEVKGSGRVLSCPGPRAVTVRYTFTEWRSFLDVPAELQPEPLEPQQPEAPSGASEPGSGDAKKEPGAECFHFSLCLPPGLQPEDEEDADERGVAVHFAVCYRCAQGEYWDNNAGANYTLRYARPADAL
What is the function of this protein?
Glycogen-targeting subunit for protein phosphatase 1 (PP1).  Involved in the regulation of hepatic glycogenesis in a manner coupled to the fasting-feeding cycle and distinct from other glycogen-targeting subunits (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 3G.
Protein: AVLA5_WHEAT
Sequence: MKTMLILALIALAATSVVAQLDTTCSQGYGQCQQQPQQQVNTCSALLQQCSPTPYVQSQMWQASGCQLMRQQCCQPLAQISEQARCHAVCGVAQVIMRQQQGQSFGQPQQQQGQSFSQPQQQVPIEIRRMVLQTLPSMCNVNIPQYCTTTPCSTITQTPYNVPMATTCVGGTC
What is the function of this protein?
Seed storage protein.  Not integrated in the gluten polymer through disulfide bonds, unless incorporated by reduction and reoxidation during dough making.  Increases dough strength and bread volume, but decreases dough stability when added into a base wheat flour.
What are the official names of this protein?
Avenin-like a5, LMW-gliadin 1111, LMGli1111.
What is the protein family that this protein belongs to?
Belongs to the prolamin family.
Protein: RSKA_MYCTO
Sequence: MTEHTDFELLELATPYALNAVSDDERADIDRRVAAAPSPVAAAFNDEVRAVRETMAVVSAATTAEPPAHLRTAILDATKPEVRRQSRWRTAAFASAAAIAVGLGAFGLGVLTRPSPPPTVAEQVLTAPDVRTVSRPLGAGTATVVFSRDRNTGLLVMNNVAPPSRGTVYQMWLLGGAKGPRSAGTMGTAAVTPSTTATLTDLGASTALAFTVEPGTGSPQPTGTILAELPLG
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK.  ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP).  RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor (By similarity).
What are the official names of this protein?
Anti-sigma-K factor RskA, Regulator of SigK, Sigma-K anti-sigma factor RskA.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-K factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: IF2G_YEAST
Sequence: MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA
What is the function of this protein?
As a subunit of eukaryotic initiation factor 2 (eIF-2), involved in the early steps of protein synthesis.  In the presence of GTP, eIF-2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex and initiation factors eIF-1, eIF-1A and eIF-3 to form the 43S pre-initiation complex (43S PIC), a step that determines the rate of protein translation.  The 43S PIC binds to mRNA and scans downstream to the initiation codon, where it forms a 48S initiation complex by codon-anticodon base pairing.  This leads to the displacement of eIF-1 to allow GTPase-activating protein (GAP) eIF-5-mediated hydrolysis of eIF2-bound GTP.  Hydrolysis of GTP and release of Pi, which makes GTP hydrolysis irreversible, causes the release of the eIF-2-GDP binary complex from the 40S subunit, an event that is essential for the subsequent joining of the 60S ribosomal subunit to form an elongation-competent 80S ribosome.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must be exchanged with GTP by way of a reaction catalyzed by GDP-GTP exchange factor (GEF) eIF-2B.
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: Y4759_VIBVU
Sequence: MNTVFEIVSQARRKNKLKRELLDNEKKVRDNRKRVELLENLLDYIKPNMSQDEIMTIIKNMKADYEDRVDDHIIKSAEISKARRDISRRIRELTEEDKQASGKK
What are the official names of this protein?
UPF0265 protein VV2_0759.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: AROA_CAMJD
Sequence: MKIYKLQTPVNTILENIAADKSISHRFAIFSLLTQGENKARNYLLAQDTLNTLEIIKNLGAKIEQKDSCVKIIPPKEILSPNCILDCGNSGTAMRLMIGFLAGISGFFVLSGDKFLNNRPMRRISKPLTQIGARIYGRNEANLAPLCIEGQNLKAFNYKSEISSAQVKTAMILSAFRADNICTFSEISLSRNHSENMLKAMKAPMRVSNDGLNLEISPLKKPLKAQNIIIPNDPSSAFYFALAAIILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVKDNIAWLIDEAPALAIAFALAKGKSNLVNAKELRVKESDRIAVMVENLKLCGVEAKEFDDGFEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDSDCIKTSFPNFIEILSNLGARIDY
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MEGGI
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFHPYYTIKDILGILLLILFLMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVSSILILILMPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEYPFIIIGQLASVLYFLIILVLMPITSTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNC_STRZP
Sequence: MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNERLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKLGKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITDYKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQEAAKNAVEKGLDSCI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_CLOTE
Sequence: MFKLAKIMIQGTGSSVGKSILVTALCRIFKQDGYTVCPYKSQNMALNSYITYDGKEMGRAQVLQAHAAGLEPEAYMNPILLKPTGDKKCQIIFNGEVYGNSTAMEYHNMKTKFGEKLKDQFKNIEEKFDIVVIEGAGSPAEINLRDKDIVNMGFAEMVDAPVLLAGDIDRGGVFASLAGTMLLLTEEERNRVKGTIINKFRGDIEILKPGLKMLEDIIKIPTVGVVPYLKFQLEDEDGAIDFNRNINAPIDIAVIKLPRISNFTDFDALKVEEDVSIRYITSKEDFGKPDLLIVPGSKNTIEDLLALRKCGLEEKIKEYSKTGTIIGICGGYQMLGKTLKDPYKVESEELETQGMGLLNVDTVFEKEKVTTRVKANSEDTEVYGYEIHMGICNYKEGAKPLFNIYDENGKKVNRNDGAINEKGNVMGTYIHGVFDGVEFREKVLNNIRKSKNMEERNAINYENLREKNLDMLADLVRENIDMDYIYKIIGM
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RBL_ACRAU
Sequence: DLTYYTPEYQTKDTDILAAFRMTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTTLDRYKGRCYDIEPVPGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYPKTFIGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKALAETGEIKGHYLNATAGTSEEMMKRARFARELGAPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREVTLGFVDLLRDDYIEKDRSRGIYFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDAVLQFCGGTLGHPWGNAPGAVANRVALEACVQARNEGRDL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CP182_THYVU
Sequence: MDISISWVVIIVSVLSYLILMDKWRAAKLPKNIPPGPPKLPLIGHLHLLRGGLPQHLLRGITQKYGPVAHVQLGELFSVVLSSTEAARQAMKVLDPNFADRFVNIGSRIMWYDSEDIIFSRYNDHWRQIRKICVSELLSPKNVRSFGYIRQDEMARLIRLFESSEGKPVNVSEEISKTVCTIVSRVAFGSAVKDQSLLMNLVKESLRMASGFELADVFPSSWLLNLLCFNKYRLWRMRARLDKFLDGFLAEHRVKKSGEFGGEDIIDVLYRMQEDSETKVPITNNGIKGFIYDVFSAGTDTSGATILWALSELMRYPEKMAKAQAEVRETLKGKTNVDMAEVHELKYLRSVVKEALRLHPPFPMIPRLCVQESEVTGYTIPANTRILINVWSIGRDPLYWEDPDTFNPDRYDEVPRDIIGNDFELIPFGSGRRICPGLHFGLANIEVPLAQLLYHFDWKLPPGMTAADIDMTEKTGLSGPRKNPLILVPIIHNPTS
What is the function of this protein?
Involved in the biosynthesis of phenolic monoterpene natural product thymol which has a broad range of biological activities acting as antimicrobial compound, insecticide, antioxidant and pharmaceutical agent (Ref. 1).  Catalyzes probably the C3-hydroxylation of gamma-terpinene to produce thymol (Ref. 1).
What are the official names of this protein?
Cytochrome P450 71D182, Gamma-terpinene hydroxylase, Thymol synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: TRPA_SALRD
Sequence: MSRLDETFDALGPDEKAMGLFLTDGFPNPDATVPLLHAIDRGGADFIELGMPFSDPLAEGRPIQRASARALSHGVTLPDTLRTVEAFREDSDTPLLLMGYVNPVFKYGVDAFCRDAAEAGVDGLILPDLPPQESDALCDAAAAHGLELVFLIAPNTSDERIRVVDERATGFVYAVSVTGLTGSDLAETPSVDEYLMHARDFVAQNPLLVGFGIKTHDDAMELSRHTDGFIVGSALINRVEALWEDPERSTTDRLDTVEGFARHLKSGTPVPTPQPNPA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: SRC8_HUMAN
Sequence: MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPVYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ
What is the function of this protein?
Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879).  Plays a role in the formation of lamellipodia and in cell migration.  Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity).  Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density (By similarity).  Plays a role in focal adhesion assembly and turnover (By similarity).  In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed:20861316).  Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (PubMed:17959782).  Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity).  Required for stabilization of KCNH1 channels at the cell membrane (PubMed:23144454).  Plays a role in the invasiveness of cancer cells, and the formation of metastases (PubMed:16636290).
What are the official names of this protein?
Src substrate cortactin, Amplaxin, Oncogene EMS1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle. Cell projection, dendrite. Cell projection. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, podosome. Cell junction. Cell junction, focal adhesion. Membrane, clathrin-coated pit. Cell projection, dendritic spine. Cytoplasm, cell cortex. Note=Colocalizes transiently with PTK2/FAK1 at focal adhesions (By similarity). Associated with membrane ruffles and lamellipodia. In the presence of CTTNBP2NL, colocalizes with stress fibers (By similarity). In the presence of CTTNBP2, localizes at the cell cortex (By similarity). In response to neuronal activation by glutamate, redistributes from dendritic spines to the dendritic shaft (By similarity). Colocalizes with DNM2 at the basis of filopodia in hippocampus neuron growth zones (By similarity).