PharMolix/UniProtQA huggingface dataset:
Protein: LANC1_MOUSE
Sequence: MAQRAFPNPYADYNKSLAENYFDSTGRLTPEFSHRLTNKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLHNVFGDPAYLQMAHSYVKQSLNCLSRRSITFLCGDAGPLAVAAVLYHKMNSEKQAEECITRLIHLNKIDPHVPNEMLYGRIGYIFALLFVNKNFGEEKIPQSHIQQICENILTSGENLSRKRNLAAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVNQGKLHSLVKPSVDFVCRLKFPSGNYPPCLDDTRDLLVHWCHGAPGVIYMLIQAYKVFKEERYLCDAQQCADVIWQYGLLKKGYGLCHGAAGNAYAFLALYNLTQDLKYLYRACKFAEWCLDYGEHGCRTADTPFSLFEGMAGTIYFLADLLVPTKAKFPAFEL
What is the function of this protein?
Functions as glutathione transferase (PubMed:25158856).  Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate (PubMed:25158856).  Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism (PubMed:25158856).  May play a role in EPS8 signaling.  Binds glutathione (By similarity).
What are the official names of this protein?
Glutathione S-transferase LANCL1, 40 kDa erythrocyte membrane protein, p40, LanC-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the LanC-like protein family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: RL31_TREPA
Sequence: MKKGLHPRYEETKVVCACGNVIVTASTVKDLRVEICSACHPFFTGKQKLVDSAGRIDRFNRRYKIRG
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL14_METVS
Sequence: MKGLGSTIVRSLPNGARLVCADNTGAKELEVIAVKNYSGTVRRLPSAGVGQIVFVSVKKGTPEMRKQVLPAIIIRQKKEYKRADGTRVKFEDNAAVIVTPEGTPKGSDIKGPVSKEAAERWPGVSRLAKIIH
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CYC_ALLMI
Sequence: MGDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLIGRKTGQAPGFSYTEANKNKGITWGEETLMEYLENPKKYIPGTKMIFAGIKKKPERADLIAYLKEATSN
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: RLMM_SHEAM
Sequence: MKNLFLYCRAGYEKDCAAEIQQRAAELGIGGFVKANRDDAYVVFQGFSPDDGDRLAKELPLDSLIFARQMFACGDLLDDFSPEDRVTPIAESLTEVERAGELRVETPDTNEAKELSAFCRKFTVPLRQALKKRGVLLDKESSRRPIVHVCFVAPNKAFTGYSLSNNSSPHFMGIPRLKFPADAPSRSTLKLDEAFIHFIPREEHETRLRSGLNAVDLGACPGGWTYQLVRRGMMVHAIDNGPMNHDLMETGQVTHHRADGFKFEPARRNIYWLVCDMVEKPARVAELMEYWAIQGWFKEAIFNLKLPMKSRYKEVSQILANMHAILKENGIHEFHLACKHLYHDRDEVTVHLWLRPSSPWI
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTF1_CTEFE
Sequence: MNYCFLVFLVYLVFAVNGEDIWKVNKKCTSGGKNQDRKLDQIIQKGQQVKIQNICKLIRDKPHTNQEKEKCMKFCKKVCKGYRGACDGNICYCSRPSNLGPDWKVSKECKDPNNKDSRPTEIVPYRQQLAIPNICKLKNSETNEDSKCKKHCKEKCRGGNDAGCDGNFCYCRPKNK
What are the official names of this protein?
Salivary antigen 1, FS-I.
What are the subcellular locations of this protein?
Secreted.
Protein: GLHA_MASCO
Sequence: MDYCRKYAAVILVMLSVFLHILHSLPDGDFIIQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNARVENHTECHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4789_VEREI
Sequence: MLLLLSPAKSLDYATPLPEGWPHSTPCFIAQSSALIALLRSRSPQQIAALMQLSAPLAALNAERYQAWQPRCSASNSRQALLAFDGDVYEGLQARTLSAPDLDWAQQHLAILSGLYGVLRPLDRIQPHRLEMGTRLATAAGGNLYQFWGRQIAEHLNHRLHDDPDPVLVNLASQEYFKAVDRKALNARVVECVFEDFKGGAYKIISFYAKRARGLMARHAITHRLSRPRQLEGFGLGGYAYAPAASDPERLVFRRKSPAA
What are the official names of this protein?
UPF0246 protein Veis_4789.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: Y3060_ACIB3
Sequence: MIHHIPNVLSKEQVQYFRNEMDKIEWVNGKVTAGTLSATVKRNQQLPEDHPLTHHLSNIILEALGTHPLFLSAAIPLDIIPPLFNRYENQESFGFHVDNSIRRIRGTNERLRTDLSCTLFLSEPEEYEGGDLVVEDTYGYHEVKLPAGDMILYPSTSLHEVTAITSGCRIASFFWVQSMVRDDAERHMLFNLDQTVQNLRMQLGDNHSEVIKLTNLYHNLMRKWAEL
What are the official names of this protein?
PKHD-type hydroxylase ABBFA_003060.
Protein: ATPB_PSEAB
Sequence: MSSGRIVQIIGAVIDVEFPRDAVPSIYEALKVQGVETTLEVQQQLGDGVVRSIAMGSTEGLKRGLNVDSTGAAISVPVGKATLGRIMDVLGNPIDEAGPIGEEERWGIHREAPSYADQAGGNELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPLVIGQDHYDTARGVQYVLQRYKELKDIIAILGMDELSEADKLLVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIAGFKGILNGDYDHLPEQAFYMVGGIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FXA2A_XENLA
Sequence: MLGAVKMEGHEATDWSSYYGEAEAYSSVGNMNAGLSMNPMNTYMSMSAMRTSANMTASSMNMSYVNTGMSPSLTGMSPGTGAMTGMGTGVPSMASHLSPSMIPMSAQTTAMNALAPYTNINSMSPIYGQSNINRSRDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKKPSLREGGGKKLSEGASSVGSAANSSSESSVGNESPHSSSSPCQEQKRSLVDMKSSQGLSPKHATSPASQAQHLLSQHHSVLSHEAQSHLKPEHHYSFNHPFSINNLMSSEQQHHHHHHHNHHHHHKMDLKAYEQVMHYSSYGSPMAGSLAMSTVTNKSGLESSPITSDTSYYQGGYSRPIMNSS
What is the function of this protein?
Acts as a transcriptional activator during early development, limiting the extent of mesoderm formation in the gastrula.  Binds to DNA via the target sequence 5'-GT[AC]AACA-3', with 5'-GTAAACA-3' being the preferred binding site.
What are the official names of this protein?
Forkhead box protein A2-A, FoxA2-A, FoxA2a, Fork head domain-related protein 3, xFD-3, Hepatocyte nuclear factor 3-beta homolog A, HNF-3-beta-A, HNF3-beta homolog A, HNF3-beta-A, xHNF3-beta-A, xbeta-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCA_SHEB5
Sequence: MKIYLVGGAVRDSLLNLPIKDKDYLVVGATPEQMLQLGYRQVGKDFPVFLHPKNQQEYALARTERKIGLGYGGFSCHASPDVTLEQDLLRRDLTINAIAQDEKGNLYDPFNGIEDINARLLRHVSDAFVEDPLRVLRVARFAARFHALGFHIAAETLALMRQISASDELNALTAERVWQEVDKSLGGPHPEVFFEVLHQCGALEVLFPEIFALFGVPQPEKWHPEIDTGVHTLMVLAQAALLTEDKSVRFAALVHDLGKALSPKEHLPKHHGHGQKGLPLIKALCTRLRVPNETRDLALLVSDQHQNVHQAFELRAETIVKIFDKADFWRKPERLTQLILACIADMRGRTGFENNPYPQGEYLTQCFLAANNVDIAAIIAAGFQGAEIKQALNLRRIEAVSQFKQKMQTKLPTDEQ
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: SYFA_STRTD
Sequence: MDLQTQLQELKTSTQAKLAEMRGEHSKELQELRVAVLGKKGSLTELLKGLKDLPSEERPTVGKMVNEVRDVLTEAFDEAAKVVEAAKIQAQLDSESLDVTLPGRQVNLGNRHILSQIAEEIEDIFLGMGFQIVDGFEVETDYYNFERMNLPKDHPARDMQDTFYITEEILLRTHTSPVQARTLDKHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQIEGLVVGKNISMGDLKGTLEMIIQKMFGAERRIRLRPSYFPFTEPSVEVDVSCFKCGGKGCNVCKNTGWIEILGAGMVHPQVLEMSGVDSEEYSGFAFGLGQERIAMLRYGINDIRGFYQGDVRFSEQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_BIFLS
Sequence: MSNRKALLGKKLGMSQVWDENGFFVPVTLVDVSTNVVTAVKTEESDGYKAVQLGYGAIDPTKVTKPLAGHFAKAGVTPRRHLVEVRTDDVDQFEAGQELAADLFEEGAEVDVTGTTKGKGFAGTIKRWGFKSYRRTHGSHKNERRPGSVGACATPSRILKGKRMAGRMGHVTATTQNLIIVSADVENGILAIKGAIPGPKGGIVLVRSAVKGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NHAA_RICRO
Sequence: MNIKKLILPAAAALGGVVIPVLIYMFFNYGKPELIKGWAIPIATDTAFVLGILSFFSRHISLELRAFIIGFSLIDDAFALIILALFYAKTINTLALLISSIIIFILFILNYRQVKQLFYYIIVGLLLCISMVKSGIHDTLCRAIIALFIPVNIKGEFNTSFKKLENLIRPFVNYFILPLFVFMNSGILLEYFAFKGICSNSILALIYGIIFGLSVGKQLGIMLFSYPFVKFKLCNLPSDTSWLKFYSIAILRGIGFTLSLFIGSNV
What are the official names of this protein?
Putative Na(+)/H(+) antiporter NhaA homolog.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROC_BORPE
Sequence: MSGNTLGTLFCVTNFGESHGPAIGCVVDGCPPGLPLEAADIQAELDRRRPGTSRHVTQRQEADQVEILSGVYEGVTTGTPIGLLIRNTDARSKDYSNIADTFRPGHADFAYWRKYGVRDPRGGGRSSARLTAPTVAAGAIAKKWLASQFGVRVRGYMSQLGPIAIPFSSWDDVPGNAFYAPNAAVVPELEAYMDQLRRDGDSVGARIEVVAEGLPAGWGEPIYDRLDADIAHAMMGLNAVKGVSLGAGFESIAQRGSEHGDEITPEGFASNHAGGVLGGISTGQPITVSLAIKPTSSIRVERRSVNRAGEPVMVQTLGRHDPCVGIRATPIAEALLALVLIDHALRQRAQCGG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ISPE_UREP2
Sequence: MKVKSFAKIDLGYSVYKKQKNFTKHDFESIFILVENIYDDIEITKIEKNIDDVHYYNETNEIYVYSRLVHKTLEWIRHTYHIKNHYRINIKKRIPIGAGLGGGSSNAAAIMKYILEFEGIKEINYKDVVNKLGADIPFFLSGYKTAYISDYGSVLEDLTGQFKLNYEVYLMNVNVNTKIVFEKFDDNSWHVIKNNFKTIIKNLKENIVVNIHNDLQEYCFELYPNIKYKYNELLSDGFYTILSGAGSSFIRIKLKNKEDLIINEN
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PEPT_BACC3
Sequence: MKEELIERFTRYVKIDTQSNEDSHTVPTTPGQIEFGKLLVEELKEVGLTEVTMDDNGYVMATLPANTDKDVPVIGFLAHLDTATDFTGKNVKPQIHENFDGNAITLNEELNVVLTPEQFPELPSYKGHTIITTDGTTLLGADDKAGLTEIMVAMNYLIHNPQIKHGKIRVAFTPDEEIGRGPAHFDVEAFGASFAYTMDGGPLGGLEYESFNAAGAKLTFNGTNTHPGTAKNKMRNATKLAMEFNGHLPVEEAPEYTEGYEGFYHLLSLNGDVEQSKAYYIIRDFDRKNFEARKNTIENIVKQMQEKYGQDAVVLEMNDQYYNMLEKIEPVREIVDIAYEAMKSLNIEPNIHPIRGGTDGSQLSYMGLPTPNIFTGGENYHGKFEYVSVDVMEKAVQVIIEIARRFEEQA
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_WOLPM
Sequence: MAIERTLSILKPDAVKNNITGNINSYIEQSGLKITAQKMMLLTKKQAELFYEIHKDRPFFGELVEFMTSGSVVVQVLVGENAVSKYRQIMGATDPKQADKGTIRGDFADDISENRVHGSDSLENARKEIAFFFAECELV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_ECO7I
Sequence: MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLLPDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQKRYPLALAVVACNTASTVSLPALREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEMLGSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEAEQLLPVLQRYGFETLEKLAVLG
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: TREA_ECOSE
Sequence: MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPHQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQPSTKEAQPTP
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUOA_ACICJ
Sequence: MADNAHYWVLLVYTFVVIALVAGMIGVSHFLGQRHLKRATIEPFESGIVTVGYARFRLPVQFYLIAMFFVIFDLEAAYLYAWATAVHAAGWTGYLVIAVFILALLAALAYLWRAGALEWGPKPRALAIVRRR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROB_SALPK
Sequence: MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLAIGKSEVRGGVSHEVVLSAIADCQQA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTC_YERP3
Sequence: MKFFALFIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATPLERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSRPTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVRVELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIVHYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPALRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVKPMVAALRGVREVGFTVLSMSISLVAVFIPLLLMAGLPGRLFREFAVTLSVAIGISLVISLTLTPMMCAWLLRSHPKGQQQRIRGFGKVLLAIQQGYGRSLNWALGHTRWVMVVLLSTIALNVWLYISIPKTFFPEQDTGRMMGFIQADQSISFQSMQQKLKDFMQIVGADPAVDSVTGFTGGSRTNSGSMFISLKPLSERQETAQQVITRLRGKLAKEPGANLFLSSVQDIRVGGRHSNAAYQFTLLADDLAALREWEPKVRAALAKLPQLADVNSDQQDKGAEMALTYDRETMARLGIDVSEANALLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQDVSSLDKMFVINSNGQSIPLSYFAKWQPANAPLAVNHQGLSAASTISFNLPDGGSLSEATAAVERAMTELGVPSTVRGAFAGTAQVFQETLKSQLWLIMAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNISAREAIFQASLLRFRPIIMTTLAALFGALPLVLSSGDGAELRQPLGITIVGGLVVSQLLTLYTTPVIYLYFDRLRNRFSKQPLMKLE
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NK1R_HUMAN
Sequence: MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS
What is the function of this protein?
This is a receptor for the tachykinin neuropeptide substance P.  It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
What are the official names of this protein?
Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CNFN_MOUSE
Sequence: MSYPVTSQPQCANTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAPYLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Cornifelin.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: UBID_SHEWM
Sequence: MSFKDLRSFIDHLESQGELKRISHPVDPNLEMTEIADRVLRAKGPALLFENPVGNDMPVLANLFGTPKRVAMALGKEDPLALREVGELLAFLKEPEPPRGFKDAIAKIPMFKQALNMPPKTVRNPPCQQVVKTGEEVDLTKLPIQHCWPGDVAPLVTWGLTITKGPRQKRQNLGIYRQQLLGRDKLIMRWLDHRGGALDFKDFKEKHPGERYPVVVALGSDPVTILGAVTPVPDSMSEYAFAGLLRGERTDVCKAISCDLEVPATSEIILEGYIDPDEMAEEGPYGDHTGYYNETDSFPVFTVTHITHRKDAIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIIDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIVVVDEDVNCRDWNDVIWAITTRMDPKRDTVMIENTPIDYLDFASPVAGLGSKMGMDATNKWEGETDREWGTPIVMDQAVKDKVDQIWADLGIDDAPTL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MI4GD_MOUSE
Sequence: MSEASRDDYKIQSFDAETQQLLKTALKDPGAVDLERVANVIVDHSLQDCVFSKEAGRMCYAIIQAESKQAGQSVFRRGLLNRLQKEYDAREQLRACSLQGWVCYVTFICNIFDYLRVNNMPMMALVNPVYDCLFQLAQPESLSREEEVDCLVLQLHRVGEQLEKMNGQRMDELFILIRDGFLLPTDLSSLARLLLLEMIEFRAAGWKTTPAAHKYYYSEVSD
What is the function of this protein?
Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop.  May participate in circularizing those mRNAs specifically enhancing their translation (By similarity).
What are the official names of this protein?
MIF4G domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the MIF4GD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PXPA_HAEIG
Sequence: MKKIDLNADIAEGFPFDESLLQLLSSANIACGLHAGGAKEMQSAVKFAKENKVRIGAHPSFPDRENFGRTAMALSSQELIAHLRYQLGALKAICDGEGAVISYVKPHGALYNQAAKDEKIARVIAQTVYQFDPHLKLMGLAGSLMLCIAEEEKLQTISEVFADRHYMPDGSLVPRSQPNAMVESDKEAIQQVLQMVTKGQVNAIDGSLVPVKAESICLHGDNQHSLQFAKRIVEELEKNHIKITA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RL6_CAMJ8
Sequence: MSRIGKQPIAIPAGVEVKLEGNLLKFKKGNLAKELDTKANVNVEIKDNNILFSPKGEDRQSRAYWGTYRALAYNIVVGLTQGFSKTLEINGVGYKAALKGKVLELSLGFSHPINYDIPEGIEIVVDKNTIAVKGSDKQVVGQVAAQIREFRPPEPYKGKGVKYSDERIIRKAGKTSKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.