PharMolix/UniProtQA huggingface dataset:
Protein: 6PGL_SALAR
Sequence: MKQTVYTASPESQQIHVWSLNHEGMLTLVQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFATESALPGSPTHISTDHHGRFVFVGSYNAGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQDRIALFTLSDDGYLAAQEPAEVNTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKNPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTETQPRGFNIDHHGKYLIAAGQKSHHIAVYEIAGAQGLLTEKGRYAVGQGPMWVVVNAY
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: YWQK_BACSU
Sequence: MENEYDMKSIKEKGVDFEDLWFSSVSDEILDNPEDENGQPFTGLAYELYPNGQIIYFTKYKNGLAHGLTCEFYENGNKKSEKEYRYGQLHGISIIWFENGRKKSEQQYEHSILISEKNWDEEGNLLNKYEIDTDSPHFEILESRRETHINLGRE
What is the function of this protein?
Immunity component of one of 6 LXG toxin-immunity modules in this strain.  They promote kin selection, mediate competition in biofilms, and drive spatial segregation of different strains, indicating that LXG toxins may help avoid warfare between strains in biofilms.  Mediates intercellular competition during biofilm formation; disruption of the operon disadvantages the bacteria, but overexpression of the cognate immunity protein restores growth in competition with wild-type.  In situ neutralizes the toxic effect of cognate toxin YqcG (PubMed:34280190).  Probably neutralizes the ability to inhibit growth of cognate toxin YwqJ.  Probably does not have immunity protein activity on other LXG toxins (Probable).
What are the official names of this protein?
Immunity protein YwqK.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA_ECOL6
Sequence: MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
What is the function of this protein?
Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge.
What are the official names of this protein?
Cyclopropane-fatty-acyl-phospholipid synthase, CFA synthase, Cyclopropane fatty acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLM8_HUMAN
Sequence: MWLPWALLLLWVPGCFALSKCRTVAGPVGGSLSVQCPYEKEHRTLNKYWCRPPQIFLCDKIVETKGSAGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDFHDPVVEVEVSVFPASTSMTPASITAAKTSTITTAFPPVSSTTLFAVGATHSASIQEETEEVVNSQLPLLLSLLALLLLLLVGASLLAWRMFQKWIKAGDHSELSQNPKQAATQSELHYANLELLMWPLQEKPAPPREVEVEYSTVASPREELHYASVVFDSNTNRIAAQRPREEEPDSDYSVIRKT
What is the function of this protein?
Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:10746781, PubMed:16339535, PubMed:9701027).  Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (PubMed:22043923).
What are the official names of this protein?
CMRF35-like molecule 8, CLM-8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, IgSF12, Inhibitory receptor protein 60, IRp60, NK inhibitory receptor.
What is the protein family that this protein belongs to?
Belongs to the CD300 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: YBEY_BORPE
Sequence: MATELSLSVQYGVADARLPRWRLRRWVQYALAGAAGDGHAGLAGAELGLRLVGLAEGRRLNREFRGRDYATNVLTFEYGTGPDGVARGDIVVCVPVLAREAREQRKTLLDHAAHLTVHGTLHALGYDHIKAGEARRMEALETAVLARMGIADPYLAA
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_THEVO
Sequence: MNRALDDEVRRLLKIKNYMARKRVEFHRQEWFRYKKLGDAWRKPRGKHSKLREHLSRRPPIVDAGFRSPAKVRGMHPSGYYEVLVYNLKDIENIDPKIQAARIASSVGSRKREEIAKRCAELNIKVLN
What are the official names of this protein?
50S ribosomal protein L32e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: LFTR_BRUA2
Sequence: MTAEAPPDDDIIEPEMLLRAYATGIFPMAEEADDPEVFWVRPEKRGVIPLDGFHIPRSLQKTIRQGIFKIRLDSNFAGVIEGCASGTGERARTWINEPIRRAYAKLFEIGHCHTVEAWYEGKLAGGLYGVTLGRAFFGESMFTRKRDASKVCLAYLVQHLSRQGFVLLDTQFTTPHLERFGALEVPRKEYEEMLERALEGIARF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP5_PICGU
Sequence: MSQLHTNSKEVHASSSNSQDDKLQKRRARLAAWNQKKASSEKSENNEDKKPKIESSKLQEWIKRRQQKSATPEVPSTEASQKPTSIKPILRARLSTSSSKQTQLVPKKRSIFDDDDEQDDAKTAKKDFRIPNEKKLPASTEEQESEDEEKVLERIRQAESGTSFLVESGFEQDLGADSGISGSEGDEEDDEEGQQRLLSEKLQKLTNKEKKLMALDYTQMEYTSVRKKFYTPPEELKDVPPEKVTALRTAMDGIKVRGSDCPMPIQKWAQLGLPSSIMTVLEEKLGYDTPSPIQSQALPAIMSGRDIIGVANTGSGKTLAFVIPLIRHIMDQPPLKSGDGPIGVILTPTRELALQIQKELVNFTQAVELSVCCCYGGSPIESQIADLKRGTEIIVGTPGRVIDLLAANGGRVTNLRRTTFLVLDEADRMFDMGFEPQVNKVLSQIRPDKQMVLFSATFPKKLESLARSFLVDPIEIVAGGISVVAPEITQRVVLIDDSGDISQKKLQALLKIVDEFSVEDPEGKILIFVDKQEAADDLMVRLLNNQISCIVIHGGKDQVDRKHAIKQFSDKNGLRVLIATSIAARGLDVRGLNLVINYDAPSHMEDYVHRVGRTGRAGATGTAVTLVLSSQEREIRDLVRAMKMSGKVDDIPAELQSIADKFLKKVKSGEEKFNSGFGGKGLENLQERRDNVREIEMQMYGDKVKETNGVSNSSAGRKALGTPEAAEIAGIKLPDFDIVEGRAPETSGPDRCKFHSRIEINDLPQKARWVVVNRDSLSKIIDATSTSITSKGQYYPPNSKLPKPTIKYGREIPPPPKLYLLVEGLTKSAVQEANKLLRQKMIEGVDVATEEDAKAPIGRYNV
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase PRP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRIS_SULTO
Sequence: MHQEQNKIIKILFSEYYEKAELDLPNDMELREFAYQPFDSETYVRHLSFSSPQELRQYILQNVPLHLYYSSARYQLPSAKEMDEKGWLGSDLLFDLDADEICEVKVRRFCPQDGYETLASNCNGEPPIEYAEITTECIMKVFEKALLIRDILKEDFGLNARIFFSGNRGFHLRVTCYEDCALLDPDDRKEIAEYFTSPKPPVIYEGNPGWSGRIAKGIEGINIDTQVTIDIRRLVRIPGSLNGKAGLMVVEIKNDKFEYGEWLSPFDGDCIFLPYVSAELTLFNNKYTVKRTYPIKIDTRIGVYLALKGLGKVKAYVR
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: ENOA_BOVIN
Sequence: MSILKVHAREIFDSRGNPTVEVDLFTAKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNAEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAENFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAIGKAGYSDKVVIGMDVAASEFYRSGKYDLDFKSPDDPSRYITPDELANLYKSFIRDYPVVSIEDPFDQDDWEAWQKFTASAGIQVVGDDLTVTNPKRIAKAVSEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTVAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK
What is the function of this protein?
Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate (By similarity).  In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses (PubMed:7499243).  May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity).  Stimulates immunoglobulin production (By similarity).
What are the official names of this protein?
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 1, HAP47, Non-neural enolase, NNE, Phosphopyruvate hydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M-band.
Protein: RL3_ROSDO
Sequence: MLRSGVIAKKVGMTRLFMEDGKQIPVTVLQLDKLQVVAQRTSEKDGYSAVQLGAGTAKAKRTSQAMRGHFAAAKVEPKRKVAEFRVDPENLIGVGEEITANHYFEGQFVDVAGTSIGKGFAGAMKRHNFGGLRASHGVSISHRSHGSTGQCQDPGKVFKGKKMAGHMGAARVTTQNLQVVRTDANRGLIMVKGAVPGSKGGWVTVKDAVKKPFPENAILPAALKSAAEEAEKAAEAAAAAAAAEAEAAAAAAAAEEQAAMEAAEAAEAKTDTVAEAEAAEKKEGDA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PDPKB_DICDI
Sequence: MINGRYQKEDVVNNNNNLNLNLIEKTLNDLTIKNNTNINNNNTNNKNTNYYNNNNFNNNNNNNNNNNNNNNNINNNNNNNKYLNNSHNNNNNNNNNNNNNNNNNNNNNNNEINNNNNNVLSHSSLSGKGGSTTYETTSYTTSITSSRDTGTISTSYESSSSSSSSSSSSLYDDDEYSDYSDSSDSIDSYVNHRQALSKSQQQQHLQQQQDQPQPLHSSMGAISNEKPPSPTNQQQQQQHHHPKHNIELPKTSSFGLQPNSSIPHKKSRSDFDFIRTIGKGAYGKVKLVIEKETQLIFASKILNKKLIIKEKKAKYVNTEKTILDSLDNPNIVKLFYTFQDENNLYFILEYCPNGDLLGALKKAGCFSIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGKNQHLKLSDFGSAKQLSIGSHHKGSRSGSFCGTAEYVCPELLTEKSAGVEADIWSYGCLLYQLVSGKLPFKGFNEYQTFLLITKREFSYPDNFDKCCMNLIDQLLDLDPYKRPTISEIKNHEFFSSIQDWSSIPSQTPPPIEQMVPQSPFPSPNSSLRLKKRSLSVGSPINSSLTYLSQPPIKPLNLDNSNIDYNDFENNQIISNNNNNNNNTTTTTTTTTTSANTSGSTNNTLYFTSPNVTSPPTSMSSNNTPRYINPLPTQSTTTTTTKPAYSSTPSSTILKSTPPPPILSSCSSNNLLGKSSNQQYQPFQFHQQQQQQQQQQQRERSSTTTPSPTFLSNHHNQHQKNLQQSFSSIDKSSFSTSSPMSSPRILLKPTELVLMDKDRKRNIREQQQIDQYQWSRFLLPNDEIILACGITEKRSGLITKKRQLIITDTPRIFYVDPVKMTQKGEITVDGSLSAQQKSSKHFIINSKGRSRHFYDLDGQSKLWVDLINELNMLSFK
What are the official names of this protein?
3-phosphoinositide-dependent protein kinase B, Pdk-class protein kinase b.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
Protein: GLGB_GLOVI
Sequence: MNPTVELRDIEALVTNLHADPFAILGPHRAEDGGAWVVRTYQPGASRVVLLGESGELAMENRRHPDLFECAVPTAPGAYRLRVEDAWGERLIEDAYRFRGSLLSDLDGHLFAEGNHHRIYEKLGAHPAVFEGVAGVYFAVWAPSARNVSVLGDFNRWDGRFHQMRRVERSTGIWELFIPELGEGTVYKFEIKNGFGHIYEKSDPYAFQQELRPKSGSVVADLDRYSWNDGEWLKRRALSNPLKQPLAIYEVHLGSWMRVPEEGDRFLSYTELADKLIPYVKDLGFTHIELLPILEHPFDGSWGYQVLGYYAPTSRFGNPTEFMAFVDRCHQSGIGVILDWVPAHFPKDGHGLALFDGTHLYEHADSRQGEHKEWGTLVFNYGRNEVRNFLIANALFWFERYHIDGIRVDAVAAMLYLDYSRHDGEWVANRYGGRENLEAIGFLRQLNELIFLYYPGALSIAEESTAWPLVTRPPYLGGLGFNLKWHMGWMHDTLAYFRTDPLFRRYRHNDITFSITYTFYENFVLALSHDEVVHMKGSIIGKMPGDGWQKFANLRALFTFMYGHPGKKTLFMGMEFAHGREWNAYQSLDWHLLDYPQHRQMQQFVRALNRLYTGQPALYEEDCNPAGFFWVDCHDVLNSVFTFVRRGKDPSEQLLFVCNFTPTYHPHYRVGVLETGFWQEIFNSDSGIYGGSNKGNLGGLWSENWAIHGQPYSLGLQLPPLGCLVFKRRKEQD
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: OCE6_LEPPU
Sequence: MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKGAGKQLIAHAMEKIAEKVGLNKDGN
What is the function of this protein?
Has antibacterial activity against Gram-negative bacterium E. coli ATCC 25922 (MIC=120 uM) but not against S. pneumoniae ATCC 700603, S. choleraesuis ATCC 14028 or against Gram-positive bacterium S. aureus ATCC 29313.  Shows no hemolytic activity and no cytotoxicity.
What are the official names of this protein?
Ocellatin-PT6.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ocellatin subfamily.
Protein: LPXD_METC4
Sequence: MSDPVFIAPKGGLTLGSVAEACGVPLPDGADPSQPVTGAAPLETAGPSELAYMDNARYGDALATTRALACLVSPRFAPRVPAGTIALVTRDPYRAYAGLLARLYEEAMRPGSLFAAAGVSPGAHVHPQARLEDGVRIDPGAVVGPGAEIGAGTVLGPNAVIGPNVRIGRDCSIGAGTTLTHALVGNRVIVHPGARIGQDGFGFAMGAGGHIKVPQVGRVIIQDDVEIGANTTIDRGASRDTVVGEGTKIDNLVQIAHNVVIGRHCVIVSGVGISGSTTLEDYVVLGGQVGVVGHLRIGMGSQIAGSSNVNRDVPPGSRWGGTPAKPVRTWFREMTTLARLAERSGKDEAEG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: PB2_I77AB
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQNCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIKVHEGYEEFTMVGKRATAILRKATRRLIQLIVSGRDEQSIVEAIVVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTSSTEMSMRGVRVSKMGVDEYSNAERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: MOAC_ACTSZ
Sequence: MTELTHINQNGEANMVDVSGKQDTVREARAEAFIGMNAETLQMIMSGNHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEVNLTALPESNQVRIESLCKLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKCGGKSGHFVAA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CXA4_BOVIN
Sequence: MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPRVERALASIERQMAKISVAEDGHLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRSPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELAYLLCRCLSRGVRARQRQDAPPAPGTSSEPYADQVFFYLPMSEGPSSPPCPTYNGLSSSEQNWANLTTEERLASSRAPLFLDPPPQTGRKSPSRPSSSASKKQYV
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction alpha-4 protein, Connexin-37, Cx37.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: YTCA_BACSU
Sequence: MKICVVGAGYVGLTLSAALASIGHDMICTDKDVKKIGQLKKGVIPFYEPGLSDAILRCGNLSFSSEVKSSMEECPVIFIAVGTPPRSDGSADTKALQSVIGDLSEAIRSYKTIITKSTVPPGTNENIAKQLIASGVSKNLFNIVSNPEFLREGNALYDMLHPDKTVIGVQEEDHVSAAIVKSIYKHIDTPFIVTSLAGAELIKYANNFFLAAKISFINEMARICEAYQSDISDISRAIGLDPRIGKHFLQAGIGYGGSCFPKDLQALQFAAQEKNTETFLLRAVQHINDTQLGLYIKKIQSFFETLQGKKAAVLGISFKPNTDDIRNSQAVRLMERLAELGCDVHAYDPEAVLPEHLRQHVTQHSQAFDAIEESDFLFLATEWSEFLAFDWKKAADIMKGRLVIDGRNVLKKELIEACGLICTGVGRP
What is the function of this protein?
Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid.
What are the official names of this protein?
Putative UDP-glucose 6-dehydrogenase YtcA, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: HBAC_LITCT
Sequence: MALNCDDKAHIRAIWPCLASHAEQYGAEALHRMFLCHPQTKTYFPNFDFHANSAHLKNHGKKVMNALTDAVKHLDHPEASLSSLSDLHAFTLRVDPGNFALLSNNILVVVAVHHSDKLSYETHQALDKFLNVVSGLLTSKYR
What is the function of this protein?
The alpha-C chain is a component of adult hemoglobin C.
What are the official names of this protein?
Hemoglobin subunit alpha-C, Alpha-C-globin, Hemoglobin alpha-C chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: VSP1_DEIAC
Sequence: MVLIRVLANLLILQLSYAQKSSELVIGGVECDINEHRFLVALYELTSMTFLCGGTLINQEWVVTAAHCDRLQLYLYIGMHDKYVKFDDEQGREPIEKYFYNCSNNLTTRDKDIMLIRLDRPVDNSTHIAPLSLPSRPPSVGSVCRVMGWGAISPSRDVLPDVPHCVNINLVNNAECRRAYPRLPATSRTLCAGVMQGGIDSCNRDSGGPLICDGQFQGVVNWGGNPCAQPNMPALYTKVYDYNDWIRSITAGNTTAACPP
What is the function of this protein?
Thrombin-like snake venom serine protease that coagulates human fibrinogen by hydrolysis of the alpha chains (FGA).
What are the official names of this protein?
Thrombin-like enzyme acutobin, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PFD5_HUMAN
Sequence: MAQSINITELNLPQLEMLKNQLDQEVEFLSTSIAQLKVVQTKYVEAKDCLNVLNKSNEGKELLVPLTSSMYVPGKLHDVEHVLIDVGTGYYVEKTAEDAKDFFKRKIDFLTKQMEKIQPALQEKHAMKQAVMEMMSQKIQQLTALGAAQATAKA
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.  Represses the transcriptional activity of MYC.
What are the official names of this protein?
Prefoldin subunit 5, Myc modulator 1, c-Myc-binding protein Mm-1.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus.
Protein: SRP54_HELPY
Sequence: MFQALSDGFKNALNKIRFQDDEKALDRALDELKKTLLKNDVHHKVARELLKKVESQTKLNGIGKQQFLDALEKSLLEILSAKGSSGFTFAQTPPTVVLMAGLQGSGKTTTTAKLAHYLKTKNKKVLLCACDLQRLAAVEQLKVLGEQVGVEVFYEENKSVKEIASNALKRAKEAQFDVLLVDSAGRLAIDKELMQELKEVKEILNPHEVLYVADALSGQDGVKSANTFNEEIGVSGVVLSKFDSDSKGGIALGITYQLGLPLRFIGSGEKIPDLDVFVPERIVGRLMGAGDIVSLAEKTASVLNPNEAKDLSKKLKKGQFTFNDFLNQIEKVKKLGSMSSLISMIPGLGNMASALKDTDLESSLEVKKIKAMVNSMTKKEQENPEILNGSRRKRIALGSGLEVSEINRIIKRFDQASKMAKRLTNKKGISDLMNLMSQAKNQTPPKMR
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.  Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: SIX3_HOTTS
Sequence: DGYILNSKGCKVSCVVSIVYCNSMCKSSGGSYGYCWTWGLACWCEGLPNSKRWTSSKNKCN
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  This toxin is active only on insects.
What are the official names of this protein?
Insect toxin BsIT3, Insect toxin 3, Bs-dprIT3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PRDX2_PIG
Sequence: LFFYPLDFTFVCPTEIIAFSDRAEEFHQLGCEVLGVSVDXQXTHLAWINTPRKEGGLGPLKIPLLADVTRNLSLDYGVLKEDEGIAYRGLFIIDGKGVLRQITVNDLPVGRXVDEALRLVQGXQYTD
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.  Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
What are the official names of this protein?
Peroxiredoxin-2, Thiol-specific antioxidant protein, TSA, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thioredoxin-dependent peroxiredoxin 2.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.