PharMolix/UniProtQA huggingface dataset:
Protein: MACB1_ECOK1
Sequence: MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAVEKVNATGGTEPVVNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SURE_CHLL2
Sequence: MNELKKPHILVCNDDGIEGEGIHVLAASMKKIGRVTVVAPAEPHSGMSHAMTLGVPLRIKEYQRNNRFFGYTVSGTPVDCIKVALSHILDDKPDILVSGINYGSNTATNTLYSGTVAAALEGAIQGITSLAFSLATYEHADFTYAGKFARKLAKKVLQQGIPADTILSVNIPNVPESEIAGVLSTSQGRSRWEENAIERNDMYGNPYYWLNGTLKLLDDSLRQDEYAVRRNYVTVTPLSCDLTNHTFLDSLNQWNLQK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XLNA_AGABI
Sequence: MYLVAFMLLAILPTGYCQLNTLAVRAGKKYFGTATDNPELGDAPYVAQLGNTADFNQITAGNSMKWDATEPSRGTFTFSNGDTVANMARNRGQLLRGHTCVWHSQLPNWVTSGNFDNSTLLSIVQNHCSTLVSHYRGQMYSWDVVNEPFNEDGSFRQSVFFQKTGTAYIATALRAARNADPNTKLYINDFNIEGTGAKSTGMINLVRSLQQQNVPIDGIGVQAHLIVGQIPSSIQQNLQNFANLGVEVAITELDIRMTLPVTQQKLEQQQEDYRTVIRACKAVSRCVGVTVWDWTDRYSWVPGVFNGEGAACPWDENLAKKPAYQGIVDGWSQ
What is the function of this protein?
Has xylanase activity.  Seems to be involved in the release of sugars from the hemicellulolytic fraction in the compost.
What are the official names of this protein?
Endo-1,4-beta-xylanase, Xylanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SLX1_AJECG
Sequence: MDNIPQSINPIPAFYCCYLLRSTVRHASLYIGSTPEPSRRLAQHNGDRTGGARKTSSEKLRPWEMVAIVSGFTNRAGALQFEWAWQHTKESRHAEVERCESEQLGTRGSSRTGKEVKRAGKPRTSLPNILENLHILLRSPYFSEWPLEVWFFSADVWQVWSQPKGNLLDNSIKVVTAFSSKEAGDTNRREILGKRIETLDTGYDALIEYVEKSQFLLESEEAIDCGVCKQRLNPRNDMIAICSHSLCRCASHLLCLSAHFLEAAGFIGKLIPKEGTCPACLGKLEWPTLMKEITLRLRGQEEVKRLLGRRRRTEQVGKRKISNHVSSEKGESEASMPSTDAKTMALPIRSHPSVGGSNFGKLGRSVGSAIRTNTDNGSVKAVTPEIEFYRRRKCNAKKNFSGLYSTPRINISDWDNAEIIE
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SODM_MYCFO
Sequence: MAEYTLPDLDYDYGALEPHISGQINELHHSKHHAAYVKGVNDAVAKLDEARANGDHAAIFLNEKNLAFHLGGHVNHSIWWKNLSPNGGDKPTGDLAAAIDDQFGSFDKFQAQFTAAANGLQGSGWAVLGYDSLGDRLLTFQLYDQQANVPLGIIPLLQVDMWEHAFYLQYKNVKADYVKAFWNVVNWEDVQNRYAAATSKTNGLIFG
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: ARNE_SALDC
Sequence: MIGVILVLASLLSVGGQLCQKQATRPLTVGGRRRHLMLWLGLALICMGAAMVLWLLVLQTLPVGIAYPMLSLNFVWVTLAAWKIWHEQVPPRHWFGVALIISGIIILGSAA
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CK2N1_RAT
Sequence: MSEVLPYGDEKLSPYGDGGDVGQIFSCRLQDTNNFFGAGQSKRPPKLGQIGRSKRVVIEDDRIDDVLKTMTDKAPPGV
What is the function of this protein?
Potent and specific inhibitor of CaM-kinase II (CAMK2) (PubMed:11182241).  Plays a role in the maintenance of long-term retrieval-induced memory in response to contextual fear (By similarity).  Modulates blood pressure and vascular reactivity via regulation of CAMK2 activity in addition to regulation of left ventricular mass (PubMed:31327268).  Mediates the NLRP3 inflammasome in cardiomyocytes via acting as an inhibitor of the MAPK14/p38 and MAPK8/JNK pathways, thereby regulating ventricular remodeling and cardiac rhythm post-myocardial infarction (By similarity).  Negatively effects insulin sensitivity and promotes lipid formation in adipose tissues independent of CAMK2 signaling (PubMed:31327268).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase II inhibitor 1, calcium/calmodulin-dependent protein kinase II inhibitor alpha, CaM-KIINalpha, CaMKIINalpha.
What is the protein family that this protein belongs to?
Belongs to the CAMK2N family.
What are the subcellular locations of this protein?
Synapse. Cell projection, dendrite. Postsynaptic density.
Protein: FETP_FRATT
Sequence: MTKVFCKKYHQELDAIPFQPLPGELGKKIHNEISNKAWQAWLAHQTILINEYRLNLIEPKAKEFLKEEMHKFLFEGKEEKPEQFSEI
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: FUT2_GORGO
Sequence: MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVNGSQPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSPIFVVTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation.  Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs.  Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition.  Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway.
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 2, Alpha(1,2)FT 2, Fucosyltransferase 2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: RECR_HAMD5
Sequence: MQTSLVIEALMESLRHLPGVGPKSAQRMAFYLLQSDRSKGIRLAESLLKAMSEIGHCGVCRTFTEQPCCDICSNVYREKMGQICVVESPSDICAIEQTGQFSGRYFVLMGRLSPLDGIGPDDIGLPLLEHRLSTEPIKEVILAMNPTVEGEATSNYIAQMCEEYGISTTKIAHGVPIGGDLEMVDETTLSHALVGRRPMNFN
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: GCSH_METSB
Sequence: MPNIRYTKDHEYIRPDPDGAVVGITDFAQSQLGDVVFVELPVIGAVLARGAEAAVVESVKAASGVNAPASGEVIEVNSALEEKPGLVNEDPNGSGWFFKLTLADPSELDALMDEEAYEAFIKTIA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: GRK1_BOVIN
Sequence: MDFGSLETVVANSAFIAARGSFDASSGPASRDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGAGDGLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISDLGLAVELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNIQDVGAFSTVKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRPDGQMPDDMKGVSGQEAAPSSKSGMCVLS
What is the function of this protein?
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade (PubMed:12686556, PubMed:16675451, PubMed:21299498).  This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination (By similarity).  May play a role in the maintenance of the outer nuclear layer in the retina (By similarity).
What are the official names of this protein?
Rhodopsin kinase GRK1, RK, G protein-coupled receptor kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Cell projection, cilium, photoreceptor outer segment. Note=Subcellular location is not affected by light or dark conditions.
Protein: NADE_HALS3
Sequence: MSAPDTVSPLDLRFSAAELAERRDRIQSFIRDTVAAAGAERCVLGLSGGIDSTTVAHLTVDELGADALHGLVMPGAVSRDQNMSDAERVAEDLGIEYDVVEIDPFVTQLTDVFPDAAGDEVAVGNARARTRAVINYFVANHGDGVVLGTGNRAEAMTGYYTKYGDQAVDCNPIGNLYKMQVRQLARDLGVPEDLVTKAPTAELWADQTDAGELGVDYDTIDAVLAVHVDGGLPASATATHLDIDPSVVETVRDLYGASKHKRAMPPAP
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RUVC_VIBC1
Sequence: MSIILGIDPGSRITGYGVIRQQGRHLQYLGSGCIRTSEKELPGRLKQIYAGVTEIITQFQPDVFAIEQVFMAKNADSALKLGQARGSAIVAAVNADLPVHEYAARLIKQAVTGTGGADKVQVQHMVQHMLKLPAKPQADAADALGVAICHANTNKTLVALAGKATSARKGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: Y191_NAUPA
Sequence: MYTAKEVILSQIKPALGCTEPAAIALNGAYLKEYVKNAKKIQLTINTNLMKNAMYVPIPNTGKKFGVKLAFALGYLCGDKTKGLNVFENIDKKCIEEAEKYINKIELDIVEGREIYIKSEAEGCEVITKKFHDYISSIKTSEKVITFESKNIDNNISDTEKWLKKISFDTLYRLIEKEKDFDFVKNAVDVNFELSKIGLNSDCGLNIGKSYKGDDIFSKIVSITVSASDARMEGVNYPAMSLVGSGNHGISAILPVWVYGKEKNFQENEIFKAVALSMLITIYIKLFIGRLSAICGAAFASGCGVAGGIAYLESNNKEVSKKAVSYVIQDINGVICDGAKMACSLKVRLGAKSGYEAAMFALEGKPVFSDGILENDITKSIQNLSRVSEAMYNVDGSIVEIMKNKII
What are the official names of this protein?
UPF0597 protein NAMH_0191.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: UVRB_FUSNN
Sequence: MENNLFKIHSDYKPTGDQPTAIDSIVKNIENGVKDQVLLGVTGSGKTFTIANVIERVQRPSLIIAPNKTLAAQLYSEYKKFFPENAVEYFVSYYDYYQPEAYIKTTDTYIEKDSSVNDEIDKLRNAATAALIHRRDVIIVASVSSIYGLGSPDTYRRMTIPIDKQTGISRKELMKRLIALRYDRNDVAFERGQFRIKGDVIDIYPSYMNNGYRLEYWGDDLEEISEINTLTGQKVKKNLERIVIYPATQYLTADDDKDRIIQEIKDDLKVEVKKFEDDKKLLEAQRLRQRTEYDLEMITEIGYCKGIENYSRYLAGKNPGDTPDTLFEYFPKDFLLFIDESHITVPQVRGMYNGDRARKESLVENGFRLKAALDNRPLRFEEFREKSNQTVFISATPGDFEVEVSDNHIAEQLIRPTGIVDPEIEIRPTKNQVDDLLDEIRKRAAKKERVLVTTLTKKIAEELTEYYIELGVKVKYMHSDIDTLERIEIIRALRKGEIDVIIGINLLREGLDIPEVSLVAIMEADKEGFLRSRRSLVQTIGRAARNVEGRVILYADIMTDSMKEAITETERRRKIQKEYNAYNHIDPKSIIKEIAEDLINLDYGIEEKKFENDKKVFRNKTDIEKEITKLEKKIKKLVEELDFEQAIILRDEMLKLKELLLEF
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_PECCP
Sequence: MPVITLPDGSQRHYDHAVSPLDVALDIGPGLAKACIAGRVNGELVDASDKIDTDAQLAIITAKDEAGLEIIRHSCAHLLGHAIKQLWPDTKMAIGPVIDNGFYYDVDIDRTLTQEDIELLEKRMHELADTDYDVIKKKVSWQEARDAFAARGETYKMAILDENISRDDRPGLYHHEEYIDMCRGPHVPNMRFCHHFKLQKTSGAYWRGDSKNKMLQRIYGTAWADKKQLASYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEAFVRMKLKSYQYQEVKGPFMMDRVMWEKTGHWENYKEAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQVRDEVNSCIKMVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAAALTENNIEFDYQPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDFSLPGRLNASYVGESNERQVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDTQSDYVNELTRKLQEAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVEAGKVAVRTRRGKDLGSLDVSEVISKLQQEIRSRSLHQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI5_FUSCO
Sequence: MENFPTEYFLNTSVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQKMLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSSDDPHPAMVNYFDDLQAGREQAHPWWALVNEHFPNVLRHFGPFCSLNLIRSTMDFFEGCWIEQYNFGGFPGSDDYPQFLRRMNGLGHCVGASLWPKDLFDERKNFLEITTAVAQMENWMVWVNDLMSFYKEFDDERDQISLVKNFVTCHEITLDEALEKLTQETLHSSKQMVAVFADKDPQVMDTIECFMHGYVTWHLCDARYRLHEIYEKVKDQDTEDAKKFCKFFEQAANVGAVAASEWAYPPVAQLASVRAKSDVKEAQKPFLSSIELVE
What is the function of this protein?
TS is a member of the terpene cyclase group of enzymes.  It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes.  It serves to branch trichothecene biosynthesis from the isoprenoid pathway.
What are the official names of this protein?
Trichodiene synthase, Sesquiterpene cyclase, TS.
What is the protein family that this protein belongs to?
Belongs to the trichodiene synthase family.
Protein: CINAL_CHLT3
Sequence: MLAEIISIGDELLIGQVVNTNATFISKCLDEIGISTRRILTVSDKPDCIERQLADSLSHADLVLTTGGLGPTHDDITKKIIADFFGLGYEFNEEAFERCKALFARRGREMPASNRSQGEVIEGSVVLQNTRGTAPGMILQNLPNYEGKFVVIMPGVPYEMQEMMRVSVVPFFQPHSKHFIKHTSLMTAGIGESTLAEQIGEVKAFLPDGSTLAFLPHSVGVRLRVSSKGENFQAVQKEHAQVVDALKARIGGYLYATTDMPLEEHIGELLKSRGLSIATAESCTGGLIANRLTNIPGSSAYFYQGFVTYSNEAKIKALGVREETLAAHGAVSEETAQEMAAGCLEKTGSDIAISTTGIAGPGGGTEIKPVGMVCIGVATSAKLGSRSFAKTMIFWADRLLNKERFSEAALNLVRELLNAS
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: ISOC1_RAT
Sequence: MAAAEPSVAALAGGGVGAGAPSGGVPVLFCFSVFARPASVPHGAGYDVLIQKFLSLYGDQVDMHRKFVVQLFAEEWGQYVDLPKGFAVSERCKLRLVPLQIQLTTLGNLTPPSTVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARILGIPVIITEQYPKGLGSTVQEIDLTGVKLVLPKTKFSMVLPEVEAALAEIPGVRSVVLFGVETHVCIQQTALELVGRGIEVHIVADATSSRSMMDRMFALERLARTGIIVTTSEAVPLQLVADKDHPKFKEIQNLIKASAPESGLLSKV
What are the official names of this protein?
Isochorismatase domain-containing protein 1, Down-regulated in nephrectomized rat kidney protein 1, DR-NR1.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: DPO3_THEP1
Sequence: MEKIENLKWKDVTFESIEIDPDAGVVLVSVEKFSSEVENLVSLLEKETRFRVIVNGAQKSNGDLKGKILSLLNGNVPYIKDVVFEGNRLILKVLGDFARDRIASKLRSTKKQLDELLPPGTEIMFEVVEPPEDLLKKEVPQPEKREEPKGEELKIEDENHIFGQKPRKIVFTPSKIFEYNKKTSVKGKVFKIEKIEGKKTVLLIYLTDGEDSLICKVFNDVEKVEGKISLGDVIVATGDLLLENGEPTLYVKGITKLPEAKRMDNSPVKRVELHAHTKFSDQDAITDVNEYVKRAKEWGFPAVALTDHGNVQAIPYFYDAAKEAGIKPIFGIEAYLVSDVEPVIRNLSYDSSFENATFVVLDFETTGLDPQVDEIIEIGAVKIQDGQIVDEYHTLIKPSREISRRSSEITGITQEMLENKRSIEEVLPEFLGFLENSIIVAHNANFDYRFLRLWIKKVMGLDWERPYIDTLALAKSLLKMRSYSLDSVVEKLGLGPFRHHRALDDARVTAQVFLRFVEMMKKIGITKLSEIENLKDTIDYTALKPFHCTILVQNKKGLKNLYKLVSDSYIKYFYGVPRILKSALIENREGLLVGSACISGELGRAALEGASDSELEEIAKFYDYIEVMPLDVIAEDEEDLDRERLKEVYRRLYRIAKKLNKFVVMTGDVHFLDPEDARGRAALLAPQGNRNFENQPALYLRTTEEMLEKAMEIFEDEEIAREVVIENPNRIADMIEEVQPLEKKLHPPIIENADEIVRSLTMKRAYEIYGDPLPEIVQKRVERELNAIINHGYAVLYLIAQELVQKSMSDGYVVGSRGSVGSSLVANLLGITEVNPLPPHYRCPECKYFKVVEDDRYGAGYDLPDKKCPVCGAPLRKDGHDIPFETFMGFEGDKVPDIDLNFSGEYQERAHRFVEELFGKDHVYRAGTINTIAEKSAVGYVRSYEEKTGKKLRKAEMERLVSMITGVKRTTGQHPGGLMIIPKDKEVYDFTPIQYPANDRNAGVFTTHFAYETIHDDLVKIDALGHDDPTFIKMLKDLTGIDPMTIPMDDPDTLAIFSSVKPLGVDPVELESDVGTYGIPEFGTEFVRGMLVETRPKSFAELVRISGLSHGTDVWLNNARDWINLGYAKLSDVISCRDDIMNFLIHKGMEPSLAFKIMENVRKGKGITEEMESEMRKLKVPEWFIESCKRIKYLFPKAHAVAYVSMAFRIAYFKVHYPLQFYAAYFTIKGDQFDPVLVLKGKEAIKRRLRELKAMTGKDVQKKNEESVLEVVLEMILRGFSFLPPDIFKSDAKKFLIEGNSLRIPFNKLPGLGDSVAESIVRAREEKPFTSVEDLMKRTKVNKNHIELMRSLGVLGSLPETEQFTLF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX_I57A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPKEAKKQLKKDLKSQGQCAGSPTKVSRRTSPALRILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: NORM_PHOPR
Sequence: MHNYRRETRQLLTLAIPVLIASVAQTSMGFVDTVMAGGVSATDMAAVSVASSIWLPAILFGVGLLIALVPIVAQLNGSGKKDKIPFEVQHGFLLALIISVPIMAILYNAGMLIDYMDVEPILAEKTIGYLHAVVYAVPAFLLFQTLRSFAEGLSLTVPGMVIGFIGLMANIPLNWIFVYGKFGFPEMGGVGCGVATAIVYWLMFFSMLVYVLVNKRLKRAGLFDVWYKPQPKAVLRLFKLGFPVAASMFFEVSLFAVIALMISPLGSIIVASHQVAINFSSLVFMLPMSLGIALSIRVGHMLGEQDLVGAKIASHCGLIVGLIMSLMTAILTIIYREEIALLYTDNADVIVLAGQLLFLAAVYQCSDAIQVVAAGALRGYKDMRAIFIRTFIAYWMLGLPVGYILGMTDWIVEPMGPHGFWIGNIVGLSAAAIMLAMRLRWIQCQSDEFQIAMSLK
What is the function of this protein?
Multidrug efflux pump that functions as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein NorM, Multidrug-efflux transporter, Na(+)/drug antiporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS13_BACCZ
Sequence: MARIAGVDIPRDKRVVISLTYVFGIGRTTAEKILAEAGISEETRVRDLTEDELGRIRDIIDRIKVEGDLRREVSLNIKRLMEIGSYRGLRHRRGLPVRGQNSKNNARTRKGPRRTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: IF1A_PYRFU
Sequence: MLMPKKERKVEGEEVIRVPLPEGNQLFGVVEQALGAGWMDVRCEDGKVRRCRIPGRLRRRVWIKVGDLVIVEPWPVQSDKRGDIVYRYTQTQVEWLLRKGKISQEFLTGGSLLLE
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: TRYB_MANSE
Sequence: MRLFLALLALGFAAVAAVPANPQRIVGGSTTTIQQYPTIVALLFSRNGNTFFQACGGIILNNRNILTAAHCPHGDAVNRWRVRSGSTFANSGGAVHNLNRVRIHPNYNSRTLDNDIAIMRTSSNIAFNNAAQPARIAGANYNVGDNQVVWAAGWGDIRSGGPPSEQLRHVQVWTVNQATCRSRYASIGRSVTDNMLCSGWLDVGGRDQCQGDSGGPLYHNGVVVGVSSWGEECALARFPGVNARVSRFANWIRNNS
What are the official names of this protein?
Trypsin, alkaline B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.