PharMolix/UniProtQA huggingface dataset:
Protein: SUHW_DROAN
Sequence: MSAAKEGKEKKPVATVVKIVEVESVSPSKDKRPTRMKLLNNLSASSPQTYPPKTDKRSGIKGSRIKILNEDVLVAPKVEKRRSTKPTSPGATATSTVKILNEKRIVPAEETALETTKIKISPPKRNKMDHYVLQPVKVENNKSASQATRGATGEDEDTIAFILGDDDEVVPASTSRSNGQEILVTEEEEEEEEDDLDEEGDSPGGSNKNSGHKAIKEIVEHVCGKCYKTFRRLMSLKKHLEFCRYDSGYHLRKAECWKNLEKIEKDGDVLEKKDICFCCCESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDYPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRSHLKHHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKLSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHIRPFACDMCEEKFKTEKQLERHVKEHSRQKRPYFSCTECKRHFRNTAQLKQHMDAGDHSEKSGEKPQRAKRSSTKVLERTDCAICDKNFDSSETLRKHIRSVHECDPDDIFGIQPPSAKRAKINKIPKVDEEEEEEMVPVALNASSGSLISSQTDDNGVVVREFLVDEGDGTAQTITLENETYTILPLDGEIAAEQITDEGVKVEGQKTPPKKSPVVKKEKRKSLGASLAAAIADNIEVPPVEEDFEGEVLTEEDLKLKENIAKLIDMLADPPILKKYGWPNAPEEMVLCKVIENCGYDLNKGAENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDEDGADNGEGN
What is the function of this protein?
Su(Hw) controls the phenotypic effect of the gypsy transposable element.  Binds specifically to a region of the gipsy element located 3' of the 5'LTR.  It is probably a transcription factor.  Could play a role in the establishment of chromatin domains.
What are the official names of this protein?
Protein suppressor of hairy wing.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPP_SALG2
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RL4_STRA3
Sequence: MANVKLFDQTGKEVSSVELNEAIFGIEPNESVVFDVVISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSAKVAEDKFVAVENLSFAAPKTAEFASVLSALSIDSKVLVILEEGNEFAALSARNLPNVTVATATTASVLDIVNADKLLVTKEAISTIEGVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: LEPW_BACSU
Sequence: MKLISNILYVIIFTLIIVLTLVVISTRSSGGEPAVFGYTLKSVLSGSMEPEFNTGSLILVKEITDVKELQKGDVITFMQDANTAVTHRIVDITKQGDHLLFKTKGDNNAAADSAPVSDENVRAQYTGFQLPYAGYMLHFASQPIGTAVLLIVPGVMLLVYAFVTISSAIREIERKTKALETDTKDSTMST
What is the function of this protein?
Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation.
What are the official names of this protein?
Signal peptidase I W, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KN14H_ARATH
Sequence: MATEQQDSQLCLATILEDFLKQRNIQVSVGVDSSSLKKADETFGGRDLPVDPSDLRRYEAARWVRNTLGVVGGRDLPADPSEEDFRIALRSGILLCNVLNRVKPGAVPKVVEAPNDPLVNQDGAALSAFQYFENLRNFLVFVEEMGIPTFEVSDFEKGGKSARIVECVLALKSYREWKQSGGSGTWRYILNSKPTTFGIAKQYKRKDSEVPVDAVTNSPSSTPSSEQPLLDQSDSNTKNDGTASSIDAIVRAVFSDMKQEDIPVIVEDMLKSVMVEYERRLATQNELLLMSAGNRDKLGSGDLGRTISGNEETLSDASYGEENVTEIVNNNMEASQDSNVEELENQDYELYAISKEKTEKQQLIIERQQTHTEELKHDLKAVKAGLSLLQMKYQQEFTSLGKHLHGLTYAATGYQRVLEENRKLYNQVQDLKGSIRVYCRVRPFLPGQKSVLTTVDHLEDSTLSIATPSKYGKEGQKTFTFNKVFGPSASQEAVFADTQPLIRSVLDGYNVCIFAYGQTGSGKTFTMMGPNELTDETLGVNYRALSDLFHLSSVRKETFSYNISVQMLEIYNEQVRDLLATNEIRNSTQDGINVPEATLVPVSTTSDVIHLMNIGQKNRAVSATAMNDRSSRSHSCLTVHVQGKDLTSGVTLRGSMHLVDLAGSERIDKSEVTGDRLKEAQHINKSLSALGDVIASLSQKNNHIPYRNSKLTQLLQDALGGQAKTLMFIHISPELEDLGETLSTLKFAERVATVDLGAARVNKDTSEVKELKEQIASLKLALARKESGADQTQLQRPLTPDKLLRKKSLGVSSSFSKSANSTRQVQTKHKPSQIDDVNSIEGQSDSASSLDLQGLVGSPSWKTPPRDGKEEDMEFIIPGSEWVDKHEDEITRSSKPENRAHTQLEKRTSSLKREATRGVDKNKCNSSVDKGLEVRKIPYEEEANESDETATSDCSETNLMWQLNVQVNMPRPASNGSSTKLKKNQSKISRVAAETRSMIPSLIPTPTRTLSLGAAISSPGQTSSRHNNSTVVVKKRQNPK
What are the official names of this protein?
Kinesin-like protein KIN-14H.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.
Protein: Y460_MYCPN
Sequence: MTAAHKQKAKLLAWLKLILWGDSISQRIFHFYIYCILLGAVLLFLPFALKTDYQKVISYEVDLQGHTISKQTASYGFLDALFLAVSAFSDTGLSTTVVSETYSVFGQTVLAILLQLGGIGFVVIAFLVWRLFKLHKKGKYSFYEKLMLQSERGGSKLGTTSEMIVVSVLFLFMVELLYGFLYTILFYFIPAFESASVFQSSGKVSNQLKALIVDSTKRLPVVHNLNLAFQYGFFHSLSAVNNAGIDLLGANSFAPYRTNWGIVIQWLAISQIIFGGIGYPVLFDAYEAIKKRRLYGKYYKHQFSLFTKLAVLTNLIVTAWCFLMLLMVEFIVITSLTNTIAHLNVEKAYLVEGLKNKSNQELQSLIFGPIPAASRVMQLWFGVISSRSAGFSVFPWSAESDIIKGIMVIAMFIGGSPSSTAGGIRTTTLAVIFLTLKAKFRGQKEVKVFKRSIDGQTVINAFLVAVFGLVSVVLIAILLPLSMQQPLSFVDSLFETTSAFGTVGLSSGATKIMALEPTRNLFNYLTLGLLMIMGQVGVSSSVLTFVKKHPQGNSFSYPREDVKVG
What are the official names of this protein?
Uncharacterized cation transporter MG322 homolog.
What is the protein family that this protein belongs to?
Belongs to the TrkH potassium transport family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBFA_PEDPA
Sequence: MARQYRSDRLSQEIEKEVSDILRRRVRDPRVEGVTITGVDVTGDLQQAKIYYSILSDKASDDQKTKAGLEKASGLIRKELGSRLSIYKTPELSFIRDESVQYGDKIDQLLNKLNRD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_THEAC
Sequence: MGSKDLFQRGSSLFPMGVNSPVRYFKDYPFYVDNASGSRIYDVDGNEYIDYCLAYGPSILGHADPDVVRAVRDQAEKGLIYGAPSEAEIRLGDIIRRSSKNIEMMRFTNSGTEATMHAIRLARAYTGRSIIVKMEGGFHGAHDYSLIRSGSGTLTFGSPSSPGVPEEVARTVVVGRYNDEANIRNIFSQYGSRIAAVITEPIMGNAGVITPEPGFLEFLRDITQKNGSLLIFDEVITGYRFAFSPYQDIIGIRPDLTTMGKIIGGGMPIGLFGGSADIMKKVSPSGDVYQSGTFSGNPVTMAAGFAALKKLQGMDYASLVRRTEKLMNGIDDILAKRKIRHVVNGYRSMFQFFFAESAKNYDEVMKADRDLYFRIFKRLMNHGVYVPPSQFETNFVSFAHSDDDISKTIEAFDLSVGEAAK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_RICFE
Sequence: MNDLKLLRSKLSTETIEELYKNLNLLKKELFNLRFQQALGELKNTSRFSLVKKSIARIKTELTKRSNSEEY
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: METK_SALPK
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLNTSTKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPAEQLILLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGRENFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAT3_ARATH
Sequence: MSERDDGLGLSLSLSLGFNQKDPSSRLNPMPLASYASSSHMQHMQQSNYNHPQKIQNTWINMFQSSERNSDMRSFLRGIDVNRAPSTVVVDVEDEGAGVSSPNSTVSSVMSGKKSERELMAAAGAVGGGRVEDNEIERASCSLGGGSDDEDGSGNGDDSSRKKLRLSKEQALVLEETFKEHSTLNPKQKMALAKQLNLRTRQVEVWFQNRRARTKLKQTEVDCEYLKRCCENLTDENRRLQKEVSELRALKLSPHLYMHMKPPTTLTMCPSCERVAVTSSSSSVAPPVMNSSSPMGPMSPWAAMPLRQRPAAGSH
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HAT3, Homeodomain-leucine zipper protein HAT3, HD-ZIP protein 3.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_LEPST
Sequence: MTNIRKNHPLLKIANNSLIDLPTPPNISSLWNFGSLLGACLIIQVITGLFLAMHYTADTTTAFSSVTHICRDVSYGWMIRYLHANGASMFFLCLFIHVGRGLYYGSFTLLETWNVGIILLFSVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVSKATLTRFFALHFILPFIISAWVMIHLLFLHETGSNNPLGMSSNSDKIPFHPYYTTKDFLGLLLLILLLMTLALFYPDLLGDPDNYTPANPLNTPSHIKPEWYFLFAYAILRSIPNKLGGVVALILSILILMIIPFLQPNKQQTMMFRPLSQFLFWILVADLLTLTWIGGQPVEDPFISIGQTASMLYFSLMIFIMPMTCLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DGTP_SALTI
Sequence: MASIDFRNKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKEQNRLEEYGLDALTGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTHDRCVVSSLRLQEGEENLNDIRRKVRQDICHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGPVPDSHRYLMKKPGYYLSEEKYIARLRKELQLAPYSRFPLTWIMEAADDISYCVADLEDAVEKRIFSVEQLYHHLYHAWGHHEKDSLFELVVGNAWEKSRANTLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPQIFAGTFNQALLEDASGFSRLLELYKNVAVEHVFSHPDVEQLELQGYRVISGLLDIYQPLLSLSLNDFRELVEKERLKRFPIESRLFQKLSTRHRLAYVEVVSKLPTDSAEYPVLEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: PIMT_THEM4
Sequence: MYEHLKRYGVSKNIIEAMNKIDRKYFVPENVKDLAYDDIPLPIGFGQTISAPHMVGIMCKELDLKEKDKVLEIGTGSGYNAAVMSLLVGKSGHIYTIERIKQLYKIATKRFKQFGLTNITCILGDGKEGFEEYAPFDKIVVTCYSKFVPNKLLEQLSDNGILLIPVGDEFVQVLKKIKKINGQISEEDLLHVKFVPLV
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C12_RAT
Sequence: MSLSVRTSALSRRSSSQNGVAGRPWGASASSVACGYGGTASGFGVGCGGLLSAASMFGSSSGFSGGSTGCSPGLGTAYGGPLGAGVGGMGIGGSSGGGSLCIFSGNDGGLLSGSEKETMQNLNDRLASYLGKVRALEEANAELENKIREWYETRRTGDSGSQSDYSKYYPLIEDLKNKIISASVSNAQLLLQIDNARLAAEDFRMKYENELALRQTVEADINGLRRVLDELTLARADLEAQTENLTEELAYMKKNHEEELQSFQAGGPGEVNVEMDAAPGVDLTKSGELRKEINSNTEQLQSSKSEVTDLKRMVQNLEIELQSQLAMKSSLEGSLAETEGGYCCQLSQMQQLIGSLEEQLQQLRADAERQNEDHQRLLGVKARLEMEIETYRRLLEGDTQGDGFDESLSLTVSKPQAPSVDSSKDPNKTRKIKTVVQEIVNGEVVSSQVQELEEAM
What is the function of this protein?
Involved in corneal epithelium organization, integrity and corneal keratin expression.
What are the official names of this protein?
Keratin, type I cytoskeletal 12, Cytokeratin-12, CK-12, Keratin-12, K12, Type I keratin Ka12.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: HCHA_PSEAB
Sequence: MSNERDTSRTPTPDHAEHNAFFPSPYSLSQYTSAKTDFDGADYPTPYNGGKKVLMIGTDERYILMQNGSMFSTGNHPVEMLLPMYHLDKAGFEFDVATLSGNPVKLEMWAMPGEDEAVKSIYAKYLPKLKAPQKLADLLEQAVADDSPYAAVFVPGGHGVLAGIPHSREVKRLLNAFLAKDRYIITLCHGPACLLAPAVEEKPEDYPFKGYEICVFPDALDTGANLEIGYMPGPLPWLVGENLQKLGVKILNKGITGQVHRDRKLLTGDSPLASNNLGKLAAKTLLEAFAR
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1343_CHLP8
Sequence: MSDTKKNSPVSSLLQHERLRVPGMYLSFMARHFVHDNILMSAGSLAFQTLLSLVPLMAVSLSILRVFPVFGSLKQNIGDFLFQNFAPAQGALMKTYLWEFIDKTSSLSTVGGIFLIVIALFLISTIDHTLNGIWEVQAPRKVMQGFTLYWTVLTLGPLLIGTSVVASSYVWYSVFAGGELLQQKVTVLSYLPLINTAIALFLLYMVVPNRKVRFRHALAGGVLAALLFELAKRWFAFYVANFATFEAIYGALSVVPMLFFWIYLEWVVVLTGAEFVFSLGYFNPEEPDEQQEFDPLQGVPEVLAVLSAVWQAQISGSFLTGKKLLTSEIIADRSKLGLIVEFLERNHFVHQTADGGLAVNVDLHSMTLYELYSQMPRELFSSEPGREEVADGEIFEQMRSGIRAALQNTMQTPLIELVNDSTQRDP
What are the official names of this protein?
UPF0761 membrane protein Cpar_1343.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HELI_EHV1B
Sequence: MESADILPGSRGTVDRRCEGSEEKITPPRPVEDFNPQLFPNEVYLNFTSMHGIQPVVARIRELSRKTVSAAMVPPLEWFERLPRLETPLDIEPLHLPFSVYLISGNAGSGKSTCIQTLNETMDCVITGATRVAAQNVYTKLSSAFATRHINTIFQEFGFRGNHVQAQLGKYQYSCSSSPPPIEELQKRDIVYYWEVLVDITRRLFESTASRGEFENIRALERLLGRAPGSLTRLAFCTNGSLPAFTRTNIVIIDEAGLLGRHLLTVVVYCWWMLNAAYKSPQYAEGKVPVIVCVGSPTQTDSLESRFEHKNLKCHVRSSENVLTHIITNRTIREYVSLSTNWAIFINNKRCQEYEFGELMKVLEYGLPITEEHMRLVDTFVVPEAYINNPANLPGWTRLYSSHKEVSAYMAKLHAHLKVSGERQFVVFTLPAYTFVKTAAFDEYKKITQQPSLSLDKWLAANASRVSNYSQSRDQDAGKTQCEYYSEHGVVVARTDVTYVLNSQVSVTTRMRKFVFGFSGTFETFDAVLKDDAFIKTQGETSVEYAYRFLSTLLFSGMINFYNFLKRPGLDEGRVREAYRRMAALTAKLIPGASVLESACDNPSGAPLNFRGLTDPPGFTGGTTNDWDDDNDVVFAALNEGAIDMLYCNYEFVRPETTQEVYSQFLMLKTMFVGRYSIFMDLFGGDFESSPFDTFVDNISYKGCEIFVGSMRGGVSSIALQTDSYTLMGYTSAPVYPFVEELARRKLHEGIAELFGAMNMPRMVLRDQHGFMSVLNVNLSEFVESVDDVELDMATAVDYGLSSKLAMTIARSQGLSLDKVAICFPRNNLRINSVYVAMSRTVSSRFLRMNLNPLRERHERDTVISEHILAALRDRDVQIVY
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase elongates using dNTPs.  Possesses helicase-like motifs and therefore may act as the helicase subunit of the complex.
What are the official names of this protein?
DNA replication helicase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae helicase family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TXC6B_CUPSA
Sequence: FANTIRLLINKVREWKNKQSS
What are the official names of this protein?
Cupiennin-6b, Cu-6b, Short cationic peptide-6b, SCP-6b.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 09 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSCA_SALG2
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLPDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTISSVKRMMGRSLADIQARYPHLPYRFKASVNGLPMIDTAAGLLNPVRVSADILKALAARASESLSGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAIAAKIALSDADTVRVNVAGWQGEITREQFNDLISALVKRTLLACRRALKDAGVDPQDVLEVVMVGGSTRVPLVRERVGEFFGRTPLTAIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPPLPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDGEIASMIKDSMSFAEQDVKARMLAEQKVEAARVLESLTGALTADAALLSAAERQCIDDAAAHLSAVAQGDDVDAIEQAIKNVDKQTQEFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GCS2_CORDI
Sequence: MIFPPSPPTLGVEWEVALADPHSRDLVPRGHEVIEKATTHLEREFLANTVELVTSVCTTVPEAIEELREGIEEVKAIAADMGLKVWAAGSHPFSDFRKQPVNEKGHYNEIIERTQYWGNQMLIWGIHVHVGISSKDRVWPIINAMLTYYPHLLALTASSPGWDGIDTGYASNRTMLYQQLPTAGLPYQFQSWDEWEAYMADQNKSGVINHTGSMHFDIRPTRYGTVEVRICDSTNLRELSAAVALTHCLIVDLERKLDRGEELPTLQDWHVAENKWRAARYGMDAEIIISRDTDEAWVTDELRSLVERLSPLARELGCYDELQGVLTICQTGASYQRQRAIYKETGSWLPVVDAVLAEM
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: CAS5_HALVD
Sequence: MSPHIDANGVPIDCLSFTVRSTWGHFKRVGRSVTKQTYRIPPRTTVAGMLAAIVGADRDSYYDVFGADNSAIAITPLSDLRTVNIPTTGLGTDPKQDVTETAGSWRTYKLTYQNTTGDRQLHSYEVLADPAYRIDVALENEEFYDSLREHLVNGTSIYPPSLGKSEYLAVIEDVEVDREPEVQDIDETLDIDSVVPISLSEAVPQGKVTYGVERSPAVMVRESGGRRTTRFDDYVYAQQASNPVRIGEQTDVAPVQVGDRTVVFR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Plasmid targeted by CRISPR locus P1 transform wild-type cells very poorly (PubMed:22767603).  This protein helps process or stabilize pre-crRNA into individual crRNA units, in vivo Cas5 and Cas6 are also required for optimal crRNA processing and/or stability (PubMed:24459147).
What are the official names of this protein?
CRISPR-associated protein Cas5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_NITSB
Sequence: MSESAIVGGGCFWCLEAIFQRVKGVHRVTSGYAGCRRQNPTYEQVCTGTTKCAEVVKIDFDPHIINYEELLHIFFAVHDPTQLNRQGADIGTQYRSVIFPLNEEQKAIAQKVIQKLNPYFENKIVTTIENPGTFYEAESYHQNYYNTHPDQGYCQVVIAPKLKKFMNMFQEYLQ
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: PYRB_METEP
Sequence: MTAQTAPAFPHRHLLGIEGLSRPDIEALLERADAAVALSRQVEKKRTVLRGRTQINLFFEPSTRTQSSFELAGKRLGADVMNMSVASSSVKKGETLIDTAATLNAMRPDIIVVRHHAAGAVHLLARKVDCAVVNAGDGAHEHPTQALLDALTIRRNKGGIEGLQVAICGDVLHSRVARSNIILLQALGARVRVIGPSTLLPTGIERFGVEVFTDMRAGLKGCDIVMMLRLQRERMNGSFVPSVKEYFRYYGLDGDKLALAKPGALVMHPGPMNRGVEIASDIADGTQSLIREQVEMGVAVRMAVLEALATHLPNG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GAL1_ECO5E
Sequence: MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKHLQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGGGFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MORC4_MOUSE
Sequence: MLLYRGAPAGPGTPGGGLARAGSVPQAFRIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKKKPCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQRPIGVFGNGFKSGSMRLGKDALVFTKNGNTLAVGLLSQTYLECIQAQAVIVPIVPFSQQNKKMIVTEDSLPSLEAILNYSIFNCEKDLLSQFDAIPGKKGTRVLIWNIRRNKDGKSELDFDTDQYDILVSDFDAEEKEIGGVTSELPETEYSLRAFCSILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDIYKPTSTNKQVRITFGFSCKYHNQFGVMMYHNNRLIKAFEKAGCQLKPTCGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALARKLNAYWKEKISQENFEPLPTSRRIPDQTWVQCDECLKWRRLPGMVDPSTLPARWFCYYNPHPKFKRCSVPEEQERIDEDLHRSKAKQQVEAAEKKQKPMESDKYQVFSNPPKTPPLQDMAELNDKTIGYEQINSPSLLPSVREESRSPPRLKSLDSSAFQISRKYKLILGEEPVEKRRKIQTEMPLSPIDYSMSGFYRRVEAATAYPEGENSPDKCSSERSTPPHLIPEYPESNKHTEENREAPALCPGSQDQDQGFLLPEELEDQMPKLVAEESNRSSENIDKDMNKGPFVAVVGVAKGVADSGAPIQLVPFNREEFVGKRKRAESWKRANPYSSAAPAATAGKGKDCQDSRSRNMPKIKTPKESEELKRTTEKLERVLAERNLFQQKVEELEQEKNHWHSEYKKAQHELVTYSTQETEGIYWSKKHMGYRQAEFQILKAELERTKEEKQELKEKLKETESHLEVLQKAQVSFRNPEGDDLERALARLTRLRVHVSYLLTSVLPHLELREIGYDSEQVDGILYTVLEANHILD
What is the function of this protein?
Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3 (By similarity).  The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0 (By similarity).
What are the official names of this protein?
MORC family CW-type zinc finger protein 4, Zinc finger CW-type coiled-coil domain protein 2.
What are the subcellular locations of this protein?
Nucleus.