PharMolix/UniProtQA huggingface dataset:
Protein: Y781_COXBU
Sequence: MSRRETPTSTISSTPTGTRTPRRRLSRKGHPVRRSPLIAKNSIFTVFDLSFEILINAVEENSLDIIKNYLRGDSFHQTAKWGLNVPPKTDFQGDTLLIKAAKKGKFLIAKALLEAGAYKEIVNKLGETALICAVRHFRVETLDLLIQYHADVKIKYKGQNLLELTLEKYSEKTKNFTLRIVQSLVAAGVELWHSDGSQIMASDKEIDEIIRNARNLQIIKKEKREAEERARTKKSKQITLQRIQRDLEYISKRLPFEENILTTPDFPQLFFEISKLVEIISDSQKENKEEFAEASISLIDALKNFGMILEKRDVPGEVKKEDTTLSRNNSLSCLSSPR
What are the official names of this protein?
Putative ankyrin repeat protein CBU_0781.
Protein: HEX_PINMG
Sequence: MKWVKSGVGILGILLTICHAVTSQGHILDITDSLKITFKTLSNFGPRAQSIQNVTIENVGIKDIPDSGWRCYFCHDQLLFPGTFNLARNQYFLRPILDNYVVLSDGFLLEFIKGCMYRITPIPRNAPIKTRDKREFTLLAEQFSVSKYDSFPKWYCETISGGNTEVGIIRNTENLKYVEDFDSSYNWFRIPHDFRSVPLQPQDRFSANHKASSVDECKYKVIPTPVKASVSKVQRNFGTTVYYGTTDTSIRGREKLFKVAEQLALKHNLGLVEITPGLTVNNGISLVVTGNYVERNIPSPDEAYSLTVTADLISIEAPALPGLINGIETIHSLSAWDMALPYGGIKDFPRFPFRGIFLDIASNFPGYNYIKKFLTVMAQYKLNKLVLPMYNNEGFRLQLNDSPRYEFQALHMIGGKRCHDLKEEKCLFSQLGSGPDSSGGYLTKAQMTDLIKTADLLNIEIIMSMNIGESARGAIVPLKQSPHSRLLYDPDDTDFVDRFYPQKDTSMNPCREETTYFYDHMLKQLKDIYNAASVPLKTIMIGSKVNFDQVLNSKYCYASNLNSTQRLMARGNLERNINGFKLNFTKRLVKTAHDNGIKEVMAIDDVFTTEFDAEGNTPNTVYDTKNSDNSTRFNATVTAVHSRYDTVRDERLWKRGDRFAELGYKVILSPPILDFNYAVEPDPDRPGDYDSVIRNISFSKLFRFVPDSRCCNIPNAIQHDCALESDCTTAGAKDSYIGTLGKLDTRKLRSLKDWNELLFPRLLIFAERSWHKSSWEDSFGPHRASVNNITRQLITNYTVPNWNDINNEESKVLGCISRKEKLRLMHEDGLKPYVEPPGARLLGGNTMRIAASTTEDSFWVQASVNGNPWTDNVKILDVNPTDSVRLRTVHPAKAELRSKEVKLNLTSLPTPRERFRKIAQDALSRRIGIDIQRARMPPMPVNPAYRPPVPLPSFDPADDRAPDLAAIAAAHPPPLPPGMPSHMMPNMPPPFPPRPPFGPPMLPPGQMRALGQQAGQALRGQGTALGPQTGQQPMPAQPRGPLTGQAAGTGVAGQTGQQPSTAGQGTQQGLPGQQRGGVLPGQWPFFPGMPAAQFPPMFNPQMQRALQMRGQGQIPQRTQGAAAGAGQSRIPQQAG
What are the official names of this protein?
Putative beta-hexosaminidase, Beta-N-acetylhexosaminidase, Chitobiase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLU_BACCR
Sequence: MHLHFTPRQIVEKLDQYIIGQKDAKKAVAVALRNRYRRSKLAENLRDEIAPKNILMIGPTGVGKTEVARRMAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSVRIVKEEMVVKVQDKAEEQANQRLVEILVPSPEKQSGFKNPLEMLFGGAQNSNQTSDTQEDVEIEKKRQDVERKLAAGLLEEEIVSIEVTEQQSSMFDMLQGTGMEQMGMNFQDALGSFMPKKTKKRKLSVKEARKLLSNEEAQRLIDMDEVTQEAVYRAEQLGIIFIDEIDKIAGKQSNSVDVSREGVQRDILPIVEGSNVATKYGSVKTDYILFVAAGAFHMSKPSDLIPELQGRFPIRVELTKLSTDDFVKILIEPDNALIKQYMALLATEGIEIEFSDEAIRKIAEIAYQVNQDTDNIGARRLHTIMEKLLEDLSFEASEITLEKITITPQYVEEKLATIAKNKDVSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UN5CL_HUMAN
Sequence: MCPQESSFQPSQFLLLVGVPVASVLLLAQCLRWHCPRRLLGACWTLNGQEEPVSQPTPQLENEVSRQHLPATLPEMVAFYQELHTPTQGQTMVRQLMHKLLVFSAREVDHRGGCLMLQDTGISLLIPPGAVAVGRQERVSLILVWDLSDAPSLSQAQGLVSPVVACGPHGASFLKPCTLTFKHCAEQPSHARTYSSNTTLLDAKVWRPLGRPGAHASRDECRIHLSHFSLYTCVLEAPVGREARKWLQLAVFCSPLVPGQSHLQLRIYFLNNTPCALQWALTNEQPHGGRLRGPCQLFDFNGARGDQCLKLTYISEGWENVDDSSCQLVPHLHIWHGKCPFRSFCFRRKAADENEDCSALTNEIIVTMHTFQDGLETKYMEILRFQASEEESWAAPPPVSQPPPCNRLPPELFEQLRMLLEPNSITGNDWRRLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQELHYLMTVMERLDCASAIQNYLSGTHGGSPGPERGGARDNQGLELDEKL
What is the function of this protein?
Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets.
What are the official names of this protein?
UNC5C-like protein, Protein unc-5 homolog C-like, ZU5 and death domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the unc-5 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein. Cytoplasm.
Protein: TPIS_NITEU
Sequence: MGRAGFVAGNWKMHGSLVRNQELLDAVVSGTRSLQNVSCVVCVPYPYIAQTQSVLEGSHVLWGGQNVSQYHHGAYTGEVSADMLADLGCRYVIVGHSERRTLFGEGNQVVAEKFRAAQERSITPILCVGETLAQRESDETEQVIAMQLDAVIDLAGIEALGQSVIAYEPVWAIGTGKTATPQQAQDVHKFIRSRIAVHSGGIAENIQILYGGSVKADNARELFTMPDIDGGLIGGASLVAAEFISICLAAQN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_HAMD5
Sequence: MIKQKTLKHVVKTTGVGLHTGKKVTLTMRPASANDGIIYRRVDLNPVVEFFADPESVRDTQLCTCLVNENNIRISTIEHLNSALAAFGIDNVIIEVDAPEVPIMDGSASPFIFLLLNSGIKELNAPKKFLKLKETIRVQKDDKWAELSPYDGFRLDFSIDFKHPAIHENTQSYGFDFSAQTFILELSRARTFGFIKDIEYLQSKGLCLGGSFDCAIVMDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFICGHNIIGAFSAFKSGHALNNQLLKAVLENQSAWEYVTFEHEEAPILFGHSLEMCFVR
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: P5I13_RAT
Sequence: MVPPPPPPSRLLLVALVGLLSLHEVVAEPAEEAGTRCPEGLWPLPPQVLPRVTYTQVRQGQAEGITFFYHPCAHLWLKLQLAVLAHLCVAKPTLIPDFSLPWDRPLVLTAWGTALEMAWIEPAWAAQWLKRQWRRRRRKQRKSVWFLSDNLFGPTPMMPAPRRGKLCGRRCVQAPTLAFALRSWRPPGVEVTSRGPRRSSLSVVKKRGLRAALGLQSTPSGLRVSLASSQSLKAQQRTLGNSSVAPVSLMTGVTEGNGRFRTEAQMPSGQGNPGGCACPGQVSPAPRAAVPPRVARGPTPRTEEAAWAAMALTFLLVLLTLATLCTRLHRNFRRSESIYWGPTSDSQDTVAAILKRRLPLPSRRIKRSRRRPLLPPTPDSGPDSESSD
What is the function of this protein?
May act as a tumor suppressor.  Inhibits tumor cell growth, when overexpressed (By similarity).
What are the official names of this protein?
Tumor protein p53-inducible protein 13.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side. Cytoplasm. Note=Associates with unknown subcellular structures in the cytoplasm.
Protein: ATH1_SCHPO
Sequence: MATRSVSMKQTSQRAASPNKTQGAKKWSAVAARGSKIAQSATNDHRNVESIKVVPENRVRGGVAAKATDSSSNVTSLASSEENVSSVSGSAKSNNSQQRVWKTDVAISAEKRTETRQRELRRWMPDPEDAGVPLAGLEESTDNVEWDQFATNEKLFGVKSHFDEDLYTSRIDRSHPKYKEKEQEADRIAKEIEGTVTNNIHIAEERGLKVDDSGLDEEDLYSGVHRSIDVVRNYTRSNAYNKNNKDQKPKNHEAPHQHPQQKVVPPDDPAIVSHRHLALPRAPGPDSRAAERFFNARRKAGPLSRREKEGQIKEFMQFSQSLKIGSLDSKQPSSTKSVAEVKVADEKQLPDASSQATPADSKEPRKEEAEKPVTSATEVSSEKVEKVDGNTSSPSKEEEKPSTEPEKPSVVTQRKETTGTKLGTKLNAKAISFKPNVAAPVFTPGKFTIPSKPAPVNASRPMMPQQSNNSEASIPSTTPQSPSVVSNGENKPSSSPVFFNGPVSSEKEPILDNFNVFKNVGEEHQGAEQIDKPFSCPPTWNTGPNSLQQTIANSRPEGNSGSAKKAAAANPMIPSIVLPNSAMPSAMPMYPTPTMPYIPVGYPVPGYTPYMRNPSQHTSVAPSPNGTPTSGNSSTVGSPMIGYMAPQFIPPYAMPQFPPSGNGRGASAPATYFVPQMGGMMAYTMNGVPPMYGQYAPNNGMMNMHYPMYGDSRRSNSQRSFNSSNGKRSNVHKNNNASNTFSHSNASTSSSLNAAPNTTAKSSSQTAPPVSKGDATEKTEKDASANQEAKP
What is the function of this protein?
Involved in post-transcriptional regulation of gene expression, probably by association with mkt1.
What are the official names of this protein?
Ataxin-2 homolog, Pab1-binding protein 1, Poly(A)-binding protein-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ataxin-2 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at the barrier septum.
Protein: GUN5_HUMIN
Sequence: ADGRSTRYWDCCKPSCGWAKKAPVNQPVFSCNANFQRITDFDAKSGCEPGGVAYSCADQTPWAVNDDFALGFAATSIAGSNEAGWCCACYELTFTSGPVAGKKMVVQSTSTGGDLGSNHFDLNIPGGGVGIFDGCTPQFGGLPGQRYGGISSRNECDRFPDALKPGCYWRFDWFKNADNPSFSFRQVQCPAELVARTGCRRNDDGNFPAVQIP
What are the official names of this protein?
Endoglucanase-5, Cellulase V, Endo-1,4-beta-glucanase V, EG V, Endoglucanase V.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 45 (cellulase K) family.
Protein: MET2B_HUMAN
Sequence: MAGSYPEGAPAILADKRQQFGSRFLSDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQEKQVDYEINAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLENKSEVCECRNNEDGPGLIMEEQHKCSSKSLEHKTQTPPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLSAVVPDKMQKAINRLSRLLKPGGMVLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU).
What are the official names of this protein?
tRNA N(3)-methylcytidine methyltransferase METTL2B, Methyltransferase-like protein 2B.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNF76_HUMAN
Sequence: MESLGLHTVTLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQKEALSFEDGQPVQLEDGSMAYIHRTPREGYDPSTLEAVQLEDGSTAYIHHPVAVPSESTILAVQTEVGLEDLAAEDDEGFSADAVVALEQYASKVLHDSQIPRNGKGQQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSTCGKTYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPPKRPRIAYLSEVKEERDDIPAQVAMVTEEDGAPQVALITQDGAQQVSLSPEDLQALGSAISMVTQHGSTTLTIPSPDADLATSGTHTVTMVSADGTQTQPVTIITSGAVVAEDSSVASLRHQQVALLATANGTHIAVQLEEQQTLEEAINVATAAMQQGAVTLETTVSESGC
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 76, Zinc finger protein 523.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRG_DEHM1
Sequence: MSKFVFVTGGVVSSVGKGITVASLGNILKSRGLSVSVQKLDPYLNVDPGTMSPYQHGEVFVTQDGAETDLDLGSYERFIDIELTADSTVTSGQVYSEVINKERRGDYLGGTIQVVPHVTQEIKARIQRLADRSKADVVIVEVGGTVGDIEGQPFLEAIRQMRNDMGRDNVIYIHVTLLPYIQSTQELKTKPTQHSVNELRRIGIQPDIIVCRADYPISEGIRDKLSLFCDVERKAVIFMPTVSTIYEVPLKLESEGVGDLLVSRLHLNASPSDLSIWRGLVEKIKEPTPAVRIALVGKYVELKDAYYSVRESLCHAAIHNGRDIQIDWVYAEDIEKNGPEEYLKHVQGIIIPGGFGIRGIEGMITAVKYARENGIPYLGLCLGMQVMVIEFARHVLQSDKAHSTEFEPDSPYPVIDLLPEQRGVDSKGGTMRLGNYPCVIQPGTMAGQAYGNKLINERHRHRFEFNNDYRDTLSKAGMVFSGLSPDGKLVEICEVSGHPFMVGSQFHPEFLSRPNRPHPLFREFINAAKKVIRDGEQPSLPLSP
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: KCNS3_HUMAN
Sequence: MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDICNTTSLENCTAK
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed:10484328).  Heterotetrameric channel activity formed with KCNB1 show increased current amplitude with the threshold for action potential activation shifted towards more negative values in hypoxic-treated pulmonary artery smooth muscle cells (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily S member 3, Delayed-rectifier K(+) channel alpha subunit 3, Voltage-gated potassium channel subunit Kv9.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 (PubMed:10484328).
Protein: HIS8_AERHH
Sequence: MSIANLARRVVRALTPYQSARRIGGKGHVWLNANEAPLAYPFTIEGGRLNRYPECQPAEVVNGYAAYAGVNPDQVLVSRGADEAIELLIRTFCEAGEDQILICPPTYGMYAISAETCGVGIVEQPLTTSRQPDWPAIADRLSDVKLVFLCSPNNPTGDLVGRDGLIALLEKARDRAIVVVDEAYIEFCPEASVVDLLARFPNLVVTRTLSKAFALAGIRCGFTLASPEVIAMLAKVIAPYPIPEPIAQIAAQALSPMGLELMQERVVELNKQKAAFKAALATLHCVKEVFEDKGNFVLVRFVDGAAVFAAMKAAGIILRDFSTKPGLDNSIRVTIGYQGEMDAVLAVLRDLPSPSF
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: NUON_PELPD
Sequence: MATDLLYGLLPEHILLGLILVLMLLEILSVDKRAGSALFIASLLAGAGVLVMQLQTGYTADIVMNEIRIDRFSEIGRLIIVSCGAILGVYSLSSEAGHKYWILIASSLLGAMIILDSAGFISLFMGIEILSLPGFALMVLNNGKSTASEGSIKYLLLSSVATALVLFGLSLVYGSTGNLNISSFTAAVATGGVQNLAASVMILSGFFLKASVFPFHGWAPDAYSSARLPVTAFLASIVKAAVVLGLVRILGNAVLNPEAVTVIALLSMLSMFYGNITAIHQTAFKKMLAYSSISHAGYMMFALVDNTGARTEALLYYVAVYAVTTITACACFSILSGEDDNLDNLNGIFRKKPVAAILLSLCVLSLAGIPPLPGFLAKFFVFKTVIASGHLTVAVLAFVASYIGTFFYLGVVLRMFRSDAETVEQPANATCLCWTWGGALLGTLALALFMLLPNIFHWVMTGI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TXND8_MOUSE
Sequence: MVKRIKNMSELKELFSDAGNKLVVVEFSAKWCGPCKTIAPVFQAMSLKYQNVTFAQVDVDSSKELAEHCDITMLPTFQMFKYTQKVTPFSRLKRVLCCLRSGPKSKMIFECHGADAKQLEKKIQELM
What is the function of this protein?
May be required for post-translational modifications of proteins required for acrosomal biogenesis.  May act by reducing disulfide bonds within the sperm (By similarity).
What are the official names of this protein?
Thioredoxin domain-containing protein 8, Spermatid-specific thioredoxin-3, Sptrx-3, Thioredoxin-6.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: HBB2_DRYME
Sequence: VHWSAEEKQL
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-2, Beta-2-globin, Hemoglobin beta-2 chain, Hemoglobin beta-II chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DRE2_ASPNC
Sequence: MAPSFVTIDTTPDFDMAPAPSFQPMSTGSPSKRTLLLAPPSIATQEEKLRDLFTAFDRSTTDLQMLDRISAGFVSLPANTYDHILVLTDTDGTRRSEALHLLTRDVYTALVPCMKAGAKLQTQDNFFGEAEEREAVLAGLIKTDAGFEKMDQPKSFAIPLRRNGKKKDAAKTETFAPAPAPAPPVQPVTVGMINNDDDYENDDDLIDEDTLLSDEDLKRPIQPPECQPKPGRRRRACKDCTCGLAARLEAEEQAEREKADKALNVMKLETEDLNELDFTVQGKTGSCGNCALGDAFRCAGCPFIGLPAFKPGQEVQILENVAQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35.  Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18.  Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit rnr2.
What are the official names of this protein?
Fe-S cluster assembly protein dre2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: RF1_DEIRA
Sequence: MANMSRLNELVSEFGLVERRLGDPQALADGREYARLTRRHRELLPLVTLVREREQAEADLSGARELLQDPDMRDPDMKELAQLEVGGLQARLAEIEAELEVLLLPTDPDDGKDVILELRAGAGGAEAGLFVMDLLRMYERYAAGLNLKLNVLDAAESDLGGASKVVAEVTGDFAFRALKWERGVHRVQRVPATESQGRIHTSTATVAVLPEAEPGEVNLDLSEVRIDVFRSQGAGGQGVNTTDSAVRAVYRAGTPDEIMVICQDGRSQIKNREKALQVLTARLAERERAAREAQERQERASQVGSGDRSEKIRTYNYPQNRVTDHRLEGEDKNHPLDAVMAGGLAPVVSALARAQREEQLLAMSQEGAEDQHGAA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARP3_PONAB
Sequence: MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEAIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS
What is the function of this protein?
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  Seems to contact the pointed end of the daughter actin filament.  In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).  Plays a role in ciliogenesis.
What are the official names of this protein?
Actin-related protein 3, Actin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus. Note=In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes).
Protein: RCF1_FUSV7
Sequence: MADGPPSIPGPLPSSFDSDQDFYNERPMQKVFRKIKEEPLIPLGIGLTSLAFVNAYRALRRGDSKQANRMFRARVAAQGFTVIAMLAGSMYYQKDREKSKELRQLQEQRDAEEKRLKWIRELEARDDEEKAMKARLEQRRQLVQAQRAEEAEAAAAAAATTEEKPEATSGGAGGILSRIGLWPQGEKKEEEKKVAEELVEETAGDKSGKKKNPKSSLGDLGEIISSQKKD
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: NHAP2_SALTY
Sequence: MDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGIGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFHLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQKHETGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISLPSGLYPMLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVTPSDLWPIAVPALILSIWMIFFARPLSVFTGLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKVVVPPVGWPVSRVGLDIHPDNPWEQFIYQLSADKWCVGAALRDLHMPNETRIAALFRNNELFHPTGSTRLQEGDVLCVIGRERDLPALGKLFSQSPPVSLDQRFFGDFILEANAKFADVALIYGLEEGTEYRDKQQTLGEIIQQLLGAAPVVGDQVEFGGMIWTVAEKEDNVVRKIGVRVAEDEAE
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVA_COXBU
Sequence: MIGHLRGIIVEKQPPYLLLEVAGVGYEITAPLSTFYHLPEPQEEILLYTHLIVREDAHTLYGFHNDHERRLFRALIKVNGVGPKLALAILSGIGPDEFVHCVLNQNIDQLVRIPGVGRKTAERLVIETKDGLSRWHTNDTPSPEGLRSSNTQPTQDAISALMALGYKPQEAKRAIDAIQKPDLSAETLIRLALKQMVLGT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PCKA_HAEIN
Sequence: MTDLNKVVKELEALGIYDVKEVVYNPSYEQLFEEETKPGLEGFEKGTLTTTGAVAVDTGIFTGRSPKDKYIVLDEKTKDTVWWTSETAKNDNKPMNQATWQSLKDLVTNQLSRKRLFVVDGFCGASEHDRIAVRIVTEVAWQAHFVKNMFIRPTEEQLKNFEPDFVVMNGSKVTNPNWKEQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMSSMMNYFLPLKGVGAMHCSANVGKDGDVAIFFGLSGTGKTTLSTDPKRELIGDDEHGWDDVGIFNFEGGCYAKTIHLSEENEPDIYRAIRRDALLENVVVRSDGSVDFDDGSKTENTRVSYPIYHIDNIVKPVSRAGHATKVIFLTADAFGVLPPVSKLTPEQTKYYFLSGFTAKLAGTERGITEPTPTFSACFGAAFLTLHPTQYAEVLVKRMQAAGAEAYLVNTGWNGTGKRISIKDTRGIIDAILDGSIEKAEMGELPIFNLAIPKALPGVDSAILDPRDTYADKAQWQSKAEDLAGRFVKNFVKYATNEEGKALIAAGPKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.