PharMolix/UniProtQA huggingface dataset:
Protein: NUOB_BRUMB
Sequence: MGLTGTNTTLVAPQPKGILDPRTGKPVGSDDAFFNDLNGELSDKGFIVTSADALITWARTGSLMWMTFGLACCAVEMMHISMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRVVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL7_YERPG
Sequence: MSTITKDQILEGVAALSVMEIVELISAMEEKFGVSAAAVAAGPAAAVAAGPAAAVEAAEEQTEFDVVLASFGENKVAVIKAVRGATGLGLKEAKDLVESAPAVLKEGVNKDEAETLKKSLEEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RS9_CHLTR
Sequence: MIQESVATGRRKQAVSSVRLRSGNGKIDVNGKTLEQYFPLEVQRATILAPLRMLGDVNSFDLIIRVSGGGVQGQVIATRLGLARAVLQEKEDMKQELKAQGFLTRDPRKKERKKYGRKKARKSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: EFTU_STRPF
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAGDNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGIVSEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMB_CALS4
Sequence: MFLQTYETYNSINDRDLKEKNVVVIDTLRATSVITTALFNGAKEVIPVSEVEEAIELSKNFDRDTFLLAGERNSQKIEGFDLSNSPLEYVPEKVKGKTIIFTTTNGTRALKKVASAEEVILGCLLNVSAVARYISKSNKDTVIVCAGTEGKFSFDDILTAGAIYEKLKSLTDFESDDLSKASYFLYKPYENNLYDIMKYGYHLRRLEELGYTEDIKFCLTVDKFDIVPKLKNGIVRTSQDF
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: NRDI_BACVZ
Sequence: MVQIIFDSKTGNVQRFVNKTDFQLIRKVDETDHVDTPFVLVTYTTNFGQVPASTQSFLEKYAHLLLGVAASGNKVWGDNFAKSADTISRQYQVPILHKFELSGTSKDVELFTQEVERVVTKSSAKMDPVK
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: YHHW_ECOLI
Sequence: MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVINDDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHSEYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDMELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHADSDSEVLLFDLPPV
What is the function of this protein?
Has quercetin 2,3-dioxygenase activity in vitro.  Its physiological role is unknown; however, may provide a mechanism that would avoid inhibition of key cellular proteins, such as DNA gyrase, by quercetin.
What are the official names of this protein?
Quercetin 2,3-dioxygenase, Quercetinase, Pirin-like protein YhhW.
What is the protein family that this protein belongs to?
Belongs to the pirin family.
Protein: GREA_RICCK
Sequence: MNTKFPITAKGFKKLEHELKHLKHVERKKISEDIAEAREHGDLSENAEYEAAREKQAFIEGRIKELEDMAARAEIIDISKLSGDNIKFGATVTLIDDDTEEKVTYIVVGEYEADITRKRVSIASPIAKALIGKSVGDFVEVTTPKGSKSYEVVEVEYKALEL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RSMA_RHOPT
Sequence: MSAIDDLPPLREVIRRHDLAARKSLGQNFLLDLNLTARIARAAGPLEGVTVVEIGPGPGGLTRALLATGAKRVIAIERDERALGALEEIAAHYPGRLDIISGDAMEFDPRPLLNGDRARIVANLPYNIATPLLIGWLCAEPWPPWYEMMVLMFQREVAQRIVAHHDDDAYGRLAVLANWRAETQMLFDISPSAFVPPPKVTSSVVRLVPRAQPEPCDRAALEQVAAAAFGQRRKMLRQSLKSLGVDPAQLTAAAGIDPARRAETVPVSGFVAMANELANSRAIRTQA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CR115_PHYSP
Sequence: MVKLFCAIVGVAGSAFPVDIDGGQSVGDLKKAIKAESEDITIPAKDLKLFLAKTEGGAWLPDDDQAALDLEDGKVHEDIQALIDGEKMKATWTIEDVLTANNMTKRKGRAPKSRQIHVLVVVPEGAFGSASETSKMDQLVEKVDKMYEQTVLGKRKYVHSEVTSTQGRQLLNDLDIRVEFVRTVPFDAGEGSSVDPYEWKRVIIENGEEVVLTEEQQRKRYRRYVEHNIGTVLKETQLCVIGVERGTNILTVKVPGREIELAGRTDLLILSDLVAMRPTEVQYLPGVKMLIEVKRDVKASNDFQALSELIALDLLVDDPVMALLTDLEGEWIFFWVAEKINSSARIHKAAINKPGEAFEVIRALLVQPPTAPADTDTTEIKLPYFQSPVKRLKLRKALPPIGEGGDNGGIRESIERYYDIASMLGPDIEMARAVARQVTRSIPTFSYFS
What is the function of this protein?
Secreted effector that, with CRN63, is critical to pathogenesis by modulating host defenses (PubMed:21071601).  Suppresses cell death elicited by the P. sojae necrosis-inducing protein or CRN63 (PubMed:21071601).  CRN115 and CRN63 may share the same molecular host targets that are involved in the cell death signal transduction pathway and that their differential activities are dependent on plant nuclear localization or not (PubMed:21071601).
What are the official names of this protein?
Crinkler effector protein 115.
What is the protein family that this protein belongs to?
Belongs to the Crinkler effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: H1_NEUCR
Sequence: MPPKKTETKAADASAAAAPAPAAAPTSAPKTKSPSTHASYLDMITDAIVALKDRAGSSRQALKKYVRANNTLGNVTDNMFDSLFNKALKNGVDKGVFEQPKGPSGGTKLAKKVAKPAPKKAAPKKETKEKKPAAAKKEGAAKKETKEKKAPAAKKAAAPKKAAAPKKEVKEKKAAAPKKKAAAPAVADKETVLTKTKSGRVAKSTAKPAAAKKAAAPKKAAASKKAEKAEPAAEKA
What is the function of this protein?
Could act as an H1-type linker histone.
What are the official names of this protein?
Histone H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYA_HALWD
Sequence: MSELESEYRLEYFETEGFHRKQCPVTDVYFWTRDPDRETCGEPPADDYSFIDNPGFDDQYSLSGMREEFLSFFESRDHDRIEPYPVAANRWRDDVLLTQASIYDFQPLVTSGQTPPPANPLCISQPCIRMQDIDNVGKTGRHTMAFEMMAHHAFNTREDASDEYAYTGEVYWKDETVRLCDAFFEHMGADLTEITYIEDPWVGGGNAGPAFEVLYRGAELATLVFMSMEQDESGEYEMKDGNRYSPMDTYVVDTGYGLERWAWVSQGTPTVYEAVYPDTIEFLKNDADVTHTTDEKELIQQAAMLSGYLDIDEIDNLASARADVADELDVDPSVLTDLLEPLESIYAIADHYRTLAYMFGDEIVPSNVGTGYLTRMVLRRTQRLIDDIGIDAPLDELVDMQAERLGYENRDTIRDIVRTEDRKYRETLSRGRRRVETLADEYADRNESIPVDELIELYDSHGIQPDMVTEIASDRGATVEIPDDFYSLVADRHTDDDTTETIEKRRDRLADLPETDRLYYDDQTGTEFEAVVLDIFEQDTGYDIVLDQTMFYPEGGGQPADHGTLTTEEETIEITDVKAQDGVILHQATENPGKGDFIRGQLDVERRRRLMQHHTATHIIGHAARKVLGDHVRQAGAQKGTDSARFDLTHYERINRIEAKTIESVANDIIRQNISVRQDWPDRHEAENEHGFDLYQGGIPPGQNIRTITIGDDIQACGGTHVTRTGDIGTIKILTTEPVQDGVERIVFAAGDAAIDAVQTTEDALYDAADVLDVTPEHVPETADRFFTEWKERGKTIDKLKSELAEARAQGVTADAVSIDGIDAVIKTVNGDADELRKTANAIVDEDAVAVLGSDVDGSAQFVVGVPEDIGINAGDVVGQLARKVGGGGGGPPDFAQGGGPDAASLEVALDDATSVLRSMHET
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F227B_MACFA
Sequence: MAGQRTCQKKSSRAGPKKMQEPPKSIEEFLKFQNWDYWPREIHFRDDDEWSCTLKKIKEDSSFVSIYTHLWENVPRIFEALLIMESKLKEYSLILQNHTSKIFKWKSMISETSSYRKLERYGEFLKKYHKKKKIMLSDEMETEKNIEGCSFTGFKANELTKLPRHLDAERIYLFILKAHNFDERVFKIWKTHFLSEASIALLHDSFWWWFLHKFRPDRENQDCLFDRISESYVTLFMSIPLSRKDAFFQIYPDCLAQAIYATFHEAFPESSYLFNDEFKEDLGNTIFLWCSGLKPQKGFWTHWKLKELSTTTIHGSKKAPAKSVKERIADSQERITTTIDFNIIKILNNPRAYVLPISKEESGLSRLTTKTASSLLCPHMAERMSSGIFFFL
What are the official names of this protein?
Protein FAM227B.
What is the protein family that this protein belongs to?
Belongs to the FAM227 family.
Protein: GR36A_DROME
Sequence: MFDWVGLLLKVLYYYGQIIGLINFEIDWQRGRVVAAQRGILFAIAINVLICMVLLLQISKKFNLDVYFGRANQLHQYVIIVMVSLRMASGISAILNRWRQRAQLMRLVECVLRLFLKKPHVKQMSRWAILVKFSVGVVSNFLQMAISMESLDRLGFNEFVGMASDFWMSAIINMAISQHYLVILFVRAYYHLLKTEVRQAIHESQMLSEIYPRRAAFMTKCCYLADRIDNIAKLQNQLQSIVTQLNQVFGIQGIMVYGGYYIFSVATTYITYSLAINGIEELHLSVRAAALVFSWFLFYYTSAILNLFVMLKLFDDHKEMERILEERTLFTSALDVRLEQSFESIQLQLIRNPLKIEVLDIFTITRSSSAAMIGSIITNSIFLIQYDMEYF
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 36a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr22e subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGB_STAS1
Sequence: MNYIVIKIGGSTLTELHETTIDDIAQLKQQDLHPIIIHGGGPFINQALEQQGVDSLFEDGLRVTTDEVMSITSQILIGKVNPQLVSKMNDENIQSIGLNGIDAKLFDVEPLNEKYGYVGEPININTAVIDHLTEEYIPVIASIGRHKTSRHLYNINADTLAYKIAQTLNAPIYLLSDIPGVMIDNKVKATLNSEHIKNYIEQEQIYGGMIPKVQDAISAIEYGCQKVVIAAGNEAHVVERIRTGKGIGTTIVL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNR5_MAIZE
Sequence: MAGKGSYVPPQYIPLYSLDTEEDRVPAVEENHATRPKLNQDPTQWSSGICACFDDPQSCCIGAICPCFLFGKNAQFLGSGTLAGSCTTHCMLWGLLTSLCCVFTGGLVLAVPGSAVACYACGYRSALRTKYNLPEAPCGDLTTHLFCHLCAICQEYREIRERTGSGSSPAPNVTPPPVQTMDEL
What are the official names of this protein?
Cell number regulator 5, ZmCNR05.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RHO_BACSU
Sequence: MKDVSISSLENMKLKELYELARHYKISYYSKLTKKELIFAILKANAEQEDLLFMEGVLEIIQSEGFGFLRPINYSPSSEDIYISASQIRRFDLRNGDKVSGKVRPPKENERYYGLLHVEAVNGDDPESAKERVHFPALTPLYPDRQMVLETKPNFLSTRIMDMMAPVGFGQRGLIVAPPKAGKTMLLKEIANSITANQPEAELIVLLIDERPEEVTDIERSVAGDVVSSTFDEVPENHIKVAELVLERAMRLVEHKKDVIILMDSITRLARAYNLVIPPSGRTLSGGIDPAAFHRPKRFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEEFKGTGNMELHLDRSLAERRIFPAIDIRRSGTRKEELLVPKEHLDRLWSIRKTMSDSPDFAEKFMRKMKKTKTNQEFFDILNQEWKQANLSSARR
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: RGS11_HUMAN
Sequence: MAAGPAPPPGRPRAQMPHLRKMERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGSDVVQWLAQKFCVSEEEALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQTPYFWTSTLRPAAELDYAIYLAKKNIRKRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAKQRSKGDRLVIACQEQTYWLVNRPPPGAPDVLEQGPGRGSCAASRVLMTKSADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSGCLPSNPWISDNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRYVLDDAQLHIYMLMKKDSYPRFLKSDMYKALLAEAGIPLEMKRRVFPFTWRPRHSSPSPALLPTPVEPTAACGPGGGDGVA
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
What are the official names of this protein?
Regulator of G-protein signaling 11, RGS11.
Protein: IMPC_ECOLX
Sequence: MIRIEILFDRQSTKNLKSGTLQALQNEIEQRLKPHYPEIWLRIDQGSAPSVSVTGARNDKDKERILSLLEEIWQDDSWLPAA
What is the function of this protein?
The imp operon is involved in UV protection and mutation, however the ImpC protein is not essential for these functions.
What are the official names of this protein?
Protein ImpC.
What is the protein family that this protein belongs to?
Belongs to the DinI family.
Protein: RCNA_SHIF8
Sequence: MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIAIKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIIGTAFWMFWRTWRGERNWLENMHGHDYEHHHHHHDHEHHQDHEHHHDQGHHHHHEHGEYQDAHARAHANDIKRRFDGREVINWQILLFGLTGGFIPCPAAITVLLICIQLKALTLGATLVVSFSIGLALTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR
What is the function of this protein?
Efflux system for nickel and cobalt.
What are the official names of this protein?
Nickel/cobalt efflux system RcnA.
What is the protein family that this protein belongs to?
Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBM8A_HUMAN
Sequence: MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSPDRRRR
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:29301961).  Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD).  The MAGOH-RBM8A heterodimer inhibits the ATPase activity of EIF4A3, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation.  The MAGOH-RBM8A heterodimer interacts with the EJC key regulator PYM1 leading to EJC disassembly in the cytoplasm and translation enhancement of EJC-bearing spliced mRNAs by recruiting them to the ribosomal 48S preinitiation complex.  Its removal from cytoplasmic mRNAs requires translation initiation from EJC-bearing spliced mRNAs.  Associates preferentially with mRNAs produced by splicing.  Does not interact with pre-mRNAs, introns, or mRNAs produced from intronless cDNAs.  Associates with both nuclear mRNAs and newly exported cytoplasmic mRNAs.  The MAGOH-RBM8A heterodimer is a component of the nonsense mediated decay (NMD) pathway.  Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the function is different from the established EJC assembly.
What are the official names of this protein?
RNA-binding protein 8A, Binder of OVCA1-1, BOV-1, RNA-binding motif protein 8A, RNA-binding protein Y14, Ribonucleoprotein RBM8A.
What is the protein family that this protein belongs to?
Belongs to the RBM8A family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein (PubMed:11030346). Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles (PubMed:19324961).
Protein: RPOZ_STRP3
Sequence: MLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSVKSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: US02_HCMVT
Sequence: MNNLWKAWVGLWTSMGPLIRLPDGITKAGEDALRPWKSTAKHPWFQIEDNRCYIDNGKLFARGSIVGNMSRFVFDPKADYGGVGENLYVHADDVEFVPGESLKWNVRNLDVMPIFETLALRLVLQGDVIWLRCVPELRVDYTSSAYMWNMQYGMVRKSYTHVAWTIVFYSINITLLVLFIVYVTVDCNLSMMWMRFFVC
What is the function of this protein?
Participates in the inhibition of the host immune response.  Early protein that redirects newly synthesized major histocompatibility complex (MHC) class I heavy chains via the SEC61 translocon to the cytosol where they undergo proteasome-dependent destruction.  In consequence, infected cells are masked for immune recognition by cytotoxic T lymphocytes.  Seems so far to be specific for HLA-A, HLA-B, and HFE loci products.  Does not interact with HLA-DR or HLA-DM.
What are the official names of this protein?
Unique short US2 glycoprotein, HQLF2, gpUS2.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US2 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: PNP_HISS2
Sequence: MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTSVFVTVVAKKDVKEGQDFFPLTVNYQERTYAAGRIPGGFFKREGRPSEGETLIARLIDRPIRPLFPEGFFNEIQIIATVVSVNPQISPDLVAMIGASAALSLSGVPFNGPIGAARVGFINDQFVLNPTMNEQKQSRLDLVVAGTDKAVLMVESEADILTEEQMLAAVVFGHQQQQIVIEAIKEFAAEAGKPRWDWTAPEANTILIEKVKSIAENRLGDAYRITEKQARYEQIDLIKADVITQVTAEDETISEGKIIDIFTALESQIVRGRILRGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGEKTDHFLFHYNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPSLSEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEDNFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITAEIMQIALNQAKSARMHILGVMEQAIPAPRADISDFAPRIYTMKIDPKKIKDVIGKGGATVRSLTEETGTSIDIDDDGTVKIAAVDKNAVQEVMSRIEDITAEVEVGVVYKGKVTRLADFGAFVALVGNKEGLVHISQIAEERVEKVSDYLAIGQEVIVKVLEIDRQGRIRLTMKELAKDQTKNEENLLQSEEGSPVQE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_MYXXD
Sequence: MRHLLGIEGWRRDELESLLDRAKAHLPGGPDTTHLLRGKVVANLFFEDSTRTRTSFHMAAKGLGASVLNWTHTGSSVSKGETLLDTARNIEATGPVAIVMRHRSSGAPHLVAKHVKCAVINAGDGTHEHPSQALLDAFTLRQRWGSLDGRTVLIVGDVLHSRVARSNLHCLKALGAQVVMCGPPTLLPPGLESLGAEVTHNLDAALPRADAVMCLRVQLERQEQAFLPSTREYARLFGLNAAREERMKAGAVVMHPGPINRGVELAPAVADGARSVILEQVSNGVAVRRAILEVCTA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GLYA_BACCR
Sequence: MVDHLKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEHVNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDADSHRINYDDVLAKAKEHKPKLIVAGASAYPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGGMILCEEQFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEEMDEIASLIAYTLKNHENEAALEEARKRVEALTSKFPMYPNL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXB_ECOLI
Sequence: MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: CI106_HUMAN
Sequence: MAYVALSDKPHLSGEVGEEACSSWNPPLFSPRPLPRLWPLPGTPFLPIRALPFSASSSGKSSLVPSPSSSAHSGFRTPCLGPDCLLCTQGCELHEGRNHMAVHSCVARAWPGDPQEVRHLNPLLCDPGSQVEPSWPWHPGLEQAAASWVGNHVSPAHRQALRGHSLGSALRALMPGGHCPLCVPCKRGCNLRGGRGKHGPRPCCPLLRKFPVLPVHPWPFPCAVWDSGWSCR
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC02913.
Protein: RS21_ACICJ
Sequence: MQVLVRDNNVDQALKALKKKLQREGVFREMKLRRHYEKPSERRAREAAEAVRRARKMERKRIEREGF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.