PharMolix/UniProtQA huggingface dataset:
Protein: CALM_METSE
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMMTSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: CLPX_PORGI
Sequence: MAKKKDEEYCSFCGMPRTQVNLMLEGVHAHICDECALRAGEVVREALQKFKSEETNNLKREDLPRPIEIKEFLDSYVIGQDDAKRFLSVAVYNHYKRLLQQEDSDGVEIEKSNIIMVGPTGTGKTLLARTIAKMLHVPFAVVDATVLTEAGYVGEDIESILTRLLQAADYDVKQAERGIVFIDEIDKIARKSDNPSITRDVSGEGVQQGLLKLLEGSIVNVPPQGGRKHPEQKMIPVDTRHILFVCAGAFDGIEKKIAQRLNTRVVGYTAGLQNRHIDRENMLRYIRPQDLKSFGLIPEIIGRLPILTHLEPLDRDALRNIMTEPKNAITKQYEKLFAMDGIKVSFTSDMLDFVVDKAIEFKLGARGLRSIVETIMMDAMFTMPSGKKKTLVVDKAYAEAHLNIDDLLQDQ
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RSMG_SALNS
Sequence: MLNKLSRLLADAGISLTDHQKTLLVAYVDMLHKWNKAYNLTSVRDPNEMLVRHILDSIVVAPYLQGQRFIDVGTGPGLPGIPLAIVLPDAHFTLLDSLGKRVRFLRQVQHELKLENITPVQSRVEAYPSEPPFDGVISRAFASLNDMVSWCHHLPGEKGRFYALKGQLPGDEIASLPDNFSVESVEKLRVPQLEGERHLVIIKSNKV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_SHEHH
Sequence: MQNMVILGATGSIGASTLSVVACNPEQYKVYALVANTNVAKMLEICIAHQPKIAHMVDAQAAQSLKQQLPSHLDIEVTTGEDELLSLVSSSDVDTVMAAIVGAAGLPSTLAAVNAGKRVLLANKESLVMSGQLFIEAMQKSGAQVLPVDSEHNAIFQCLSERSQLEIGRCDLAGAGVSHILLTGSGGPFLTSDLATLSAMTPEQACKHPNWSMGRKISVDSATMMNKGLEYIEARWLFNASSEQLKVVIHPQSVIHSMVQYRDGSVLAQLGNPDMRTPIAHCMAFPQRINSGVEPLDFFKVGQLSFLEPDFTRFPCLALAIEACKQGQEATTVLNAANEISVQAFLDGKIRFTDIARINEQSLMNTATHPLNSIDDILALDFQSRQSTLDAITKLN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: A1AG_BOVIN
Sequence: MALLWALAVLSHLPLLDAQSPECANLMTVAPITNATMDLLSGKWFYIGSAFRNPEYNKSARAIQAAFFYLEPRHAEDKLITREYQTIEDKCVYNCSFIKIYRQNGTLSKVESDREHFVDLLLSKHFRTFMLAASWNGTKNVGVSFYADKPEVTQEQKKEFLDVIKCIGIQESEIIYTDEKKDACGPLEKQHEEERKKETEAS
What is the function of this protein?
Functions as transport protein in the blood stream.  Binds various ligands in the interior of its beta-barrel domain (By similarity).  Appears to function in modulating the activity of the immune system during the acute-phase reaction (By similarity).
What are the official names of this protein?
Alpha-1-acid glycoprotein, Orosomucoid, OMD.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CB27_TOBAC
Sequence: MTASTMALSSPSFAGNAVKLSPSSSEITGNGKAIMRKTVTKAKPVSSGSPWYGPDRVKYLGPFSGEAPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHCRWAMLGALGCVFPELLARNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLVHAQSILAIWACQVVLMGAIEGYRVAGGPLGEVTDPLYPGGSFDPLGLADDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLDNLVDHLADPVNNNAWAYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 7, chloroplastic, LHCII type I CAB-7, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: G6PI_NITMU
Sequence: MITPLTQRPAWKALEAHYQTIKGMHLRQLFADDPKRGERFTAEAVGLYLDYSKNRITDETLHLLVQLAEECGLRERIEAMFRGDAINVTEQRAVLHIALRAPRNEKILVDGNDVVPGVHAVLDRMADFSDKIRSGDWQGHTGKRIRNIINIGIGGSDLGPVMAYEALRHYSLHNLSFRFISNVDGTDFVEATRGLDPEETLFIICSKTFTTTETLANAHTARRWMLRQIKDLEGVRKHFVAVSTNAEEVARFGIDTANMFEFWDWVGGRYSMDSAIGLSTMIAVGPENFREMLAGFHAMDQHFYSAPFDRNLPVLMGLLSLWYNNFFGAQTLAVLPYEQYLKRFPAYLQQLTMESNGKHITLNGSQVDYQTSPIVWGEPGTNGQHSFYQLIHQGTRLIPCDFIGFCQTLNPLGDHHDLLMANLFAQTEALAFGKTEDEVKAEGVPDWLCPHRSFEGNRPTNTILAERLTPHTLGALVALYEQSVFTQGTIWQIDSFDQWGVELGKVLAHRIGQELEDENGKSLKHDSSTNALIQRYNRLKQK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTH_YERPN
Sequence: MALVSQARSLGKYFLLFDNLLVVLGFFVVFPLISIRFVDQLGWAALVVGLALGLRQLVQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFALMAMADEPWILWLACALSGLGGTLFDPPRTALVIKLTRPHERGRFYSLLMMQDSAGAVIGALIGSWLLQYDFHFVCWTGAAIFVLAAGWNAWLLPAYRISTVRAPMKEGLMRVLRDRRFVTYVLTLTGYYMLAVQVMLMLPIVVNELAGSPAAVKWMYAIEAALSLTLLYPLARWSEKRFSLEQRLMAGLLIMTLSLFPIGMITHLQTLFMFICFFYMGSILAEPARETLGASLADSRARGSYMGFSRLGLALGGALGYTGGGWMYDTGKTLDMPELPWFLLGIIGLITLAGLYWQFNRRRIESAMLSSS
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSTT_PROMH
Sequence: MDKQQSRVLNLLFQGSLVKQILAGLIAGILLAWLAPEVAKMMSLLGNLFISALKAVAPVLVWVLVMASIANHRQGQKTSIRPILVLYLLATFFAALTAVVASFVFPSVLTLVVNDSQLSPPENIAEVLKGVLINVVANPVDALINGNYMGILAWAIGLGLALRHASDTTKALTQDFADAVTNLVRVVIRLAPIGIFGLVSSTIATTGFKALAGYLHVLLVLIGCMLFVALVVNPLIVFWKIRRNPYPLVWACLRESGVTAFFTRSSAANIPVNMAMCRRMNLNEDTYSVSIPLGATINMGGAAITITILTLAAVNTLGMPVDIPTALLLSLVAAICACGASGVAGGSLLLIPLACSMFGISNDLAMQVVAVGVMIGVLQDSAETALNSSTDVLFTATVCIAEDERLVANPLTEKNNG
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSH1_ALIF1
Sequence: MTEFINRLQKVASNPNAFKKTGRGIERETLRFTLGASLSTKPHPEGVGSALTHKYITTDFAESLLEFITPVSNDVDTVLKQLEDVHHYTVSHMGDEKLWPLSMPCFVTHDDDITLAQYGESNVGKLKTTYREGLKRRYGSVMQVISGVHFNFSFSTEFWDELFGEQSEDQRKESVSDAYFALIRNYYRFGWLIPYFFGASPALCSSFIQGRETSMDFESLGKTYYLPYATSLRLSDLGYTNDAQSNLKISLNSVNEYVDGLNKAIRTPSEEFAKIGLKEGDKHIQLNSNVLQIENELYAPIRPKRVTKSGERPSEALERDGVEYIEVRSLDVNPYSPIGVNEDQVRFLDMFLTWTVLSDSAPMNDSEMACWKDNWNKIIEKGRKPGLELKIGCQGERLTQKAWAERVFEDLLVIAKEMDRVNGDDAYQQTHKRLSAMIDDPELTISGRLLAETKAAGGIGVIGCKLAVEHRETHLAHQYRFYTKQELDAEVERSVQAQKEIEANDKLSFSEYLEEYFSYLK
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: RBFA_THEMA
Sequence: MNPAYRKAMLESEIQKLLMEALQQLRDPRLKKDFVTFSRVELSKDKRYADVYVSFLGTPEERKETVEILNRAKGFFRTFIAKNLRLYVAPEIRFYEDKGIEASVKVHQLLVQLGYDPLKDKEKKEEDKEEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_BRUMB
Sequence: MIEHNPTTIYGTTIVTVRKDGKVVIAGDGQVSLGNTVMKGNARKVRRIGKGNVIAGFAGATADAFTLLERLEAKLEQYPDQLMRASVELAKDWRTDRYLRKLEAMMLVADSKVTLALTGTGDVLEPEQGVMAIGSGGNYALAAARALIETDKSAEEIARKAMNIAADICIYTNHNIIVESLDAQ
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUZL_BACSU
Sequence: MVREKKNPSSAAVSAASVKGDAGPTQHYGGGKRTSQNQQYKKHNMGQS
What are the official names of this protein?
Uncharacterized protein YuzL.
Protein: KCY_PSEPW
Sequence: MNSQAPVITIDGPSGSGKGTVAGLLARELGWRLLDSGALYRLLAFNASNHGVDLTNEELLKALAAHLDVQFIAAEPGKLQQIILEGEDVSNVIRTETVGAGASMVASLPAVREALLQRQRAFRETPGLIADGRDMGTVVFPDAPLKVFLTASAEERARRRYLQLKGKGEDVSLSSLLDEIRARDERDTQRAVAPLKPAADAIQLDSTELSIEQVLHRIRSELAQRDLV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STR3_SCHPO
Sequence: MEAKETHSISDHEVELQDAKPEEKSENGNFVFEKAFSSDEEKGSGYNTNETYSKMDNSLQHRGVSKIEAVRDSIYQNKRGMYLAYAFGIAILACSWASAIQSSTTYSYQVYATASFNRTSMISTLEIATAIISSVCKPILGKFSDITSRPMTYTLVLLFYVIGFIVVASSSTISAYVIGSVFISIGSSGLDYLNTLVVGDLTSLKWRGFMTALLSTPYIATVWFTGFIVQGIIDSNWRWGYGMFAIIMPAVMTPAVIILMYLERQANKDENIKKIINYQTEEKNKNKQSKWQKLWKAVLEVDLFGLILLGVGWSILLLPFSLTSYAKNGWKNPSMIAMMVVGGVILIAYSGYEMFIAPYPSCPRRVMNRTFITAVIIDFFYYLAGYLQSMYFTTYTWILYDWSYRDWTYFNNTMTIALCVFGVFAGAMHRVFHRYKYLQIIGLVIKIVGYGILIRPNFAATGKVDLAWSLILIGMGGSFSVVGSQVSCQASVPHQDLAIASSLLPLYTNIGGAIGAAIASPIFSNKVPKYLREYLPSSINDTQVYNFYSDSSLIREYPVGTEIRDGAIKAYSRSMFFLLVPAVSLSFIPLAAAFWQSNFYLGNQQNAVEGDQDHKKKGDKETTQEEKIII
What is the function of this protein?
Low affinity heme transporter involved in the assimilation of exogenous heme during conditions of low cellular iron.
What are the official names of this protein?
Low affinity heme transporter str3, Siderophore iron transporter 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 049L_IIV6
Sequence: MDKIEELKIEELKIEIPQRKTKFFHDSENSDKRDEEETLNPTITSKAKILIKSKNFWIETLIFVISVFGALCVAFGIMLIGFLLWLVSNTISILYFIKQKQYPLSLQQMVFLITTCIGVYNNV
What are the official names of this protein?
Transmembrane protein 049L.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LOX_LENH9
Sequence: MVVVNGYKQNENEKKLNVLNLDQLEKQAKEIIPTGGFGYISGGSEDEWTLRENRRAFTHKQIVPRALTNIEKPELETNVFGIPLKTPLFMVPAAAQGLAHVKGEVDTAKGVAAVGGLMAQSTYSSTSIADTAASGTGAPQFFQLYMSKDWDFNEALLDEAKRAGVKGIILTVDATVDGYREADIINNFQFPIPMANLTKYSEDDGQGKGIAEIYASAAQKIGSDDVARIANYTDLPVIVKGIESPEDALYAIGAGASGIYVSNHGGRQLNGGPASFDVLEDVAKAVNGKVPVIFDSGIRRGSDVFKALASGADLVGIGRPVIYGLALGGAQGVQSVFEHLDHELEIIMQLAGTKTISDVKNAKLLNIRY
What is the function of this protein?
Catalyzes the oxidation of (S)-lactate (L-lactate) to pyruvate, with a reduction of O2 to H2O2 (PubMed:34555022).  May be involved in the utilization of L-lactate as an energy source for growth (By similarity).
What are the official names of this protein?
L-lactate oxidase, LOX.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Protein: RECF_PSEA8
Sequence: MSLTRVSVTAVRNLHPVTLSPSPRINILYGDNGSGKTSVLEAIHLLGLARSFRSARLQPVIQYEEAACTVFGQVMLANGIASNLGISRERQGEFTIRIDGQNARSAAQLAETLPLQLINPDSFRLLEGAPKIRRQFLDWGVFHVEPRFLPVWQRLQKALRQRNSWLRHGKLDPASQAAWDRELSLASDEIDAYRRSYIQALKPVFEETLAELVSLDDLTLSYYRGWDKDRDLLEVLASSLLRDQQMGHTQAGPQRADLRIRLSGHNAAEILSRGQQKLVVCALRIAQGHLINRAKRGQCVYLVDDLPSELDEQHRMALCRLLEDLGCQVFITCVDPQLLKDGWRTDTPVSMFHVEHGKVSQTTTIGSEA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOK7_TAKRU
Sequence: MTDSVVVEGYARLRDGKKWKTRWLVLRKPSPVADCLLLLVFKDKSDKVQGNKERLSATLEELCGLEVGPWYEGVAFTLAILCLTQTTLLGFDSKEALLAWDARLRYSLGEVHRFSVGVLPGTKLESGPATLHLCNNLLALARDVPPVIVGHWNLPDLRRYGPVPNGFVFEGGTRCGYWAGVFLLASVESEQISFLFDCIVRGISPTRGPFGLRPVLPDPSTSETSSEERLNHETLELEKRLSMLSHRSSTASYCPSAGGDDRSISGSSDTSDTSHSDCSVGSRLTIWTEPTSIQPENLGNAGAKAAAQSAEKPLPSGQGGGSQPPTKPPRQLQEIGRQSSSDSGIATGSHSSYSGSFSSYTGSLDSNTGEDYGSVFSLPPHLGQDVRPCTCLNVPGHEYQIPTSLRYLYDTPRSVLQEVGGDTKDNQPPAALGPTTEPAEGDKRSPGEGHLATADGDSPNEHFRSPSESKKSSEAPSGGHPGSCCFKTIVTICAVCGGFKVS
What is the function of this protein?
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis.  Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes (By similarity).
What are the official names of this protein?
Protein Dok-7, Downstream of tyrosine kinase 7.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Synapse. Note=Accumulates at neuromuscular junctions.
Protein: INSC9_ECOLI
Sequence: MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVEYGRAKKWIAHAPLLPGDGE
What is the function of this protein?
Involved in the transposition of the insertion sequence IS2.
What are the official names of this protein?
Transposase InsC for insertion element IS2-9.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: SYE_VIBCH
Sequence: MTVKTRFAPSPTGYLHVGGARTALYSWLYAKSQGGEFVLRIEDTDLERSTQAAVDAIIEGMTWLGLEWDEGPYYQTKRFDRYNQVIDQLLAEGKAYKCYAPKELLDEIRAEQEANKEMPRYDANHPKIKAVNDAAKEGEPCCIRFRNPKEGSVVFDDQIRGRIEIRNDQLDDLIIRRTDGTPTYNFCVVVDDVDMGISHVIRGEDHINNTPRQINIYKAMGATIPTFAHCAMILGDDGAKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWGHGDQEIFSRDEMINLFSLNAISKSASAFNTDKLLWLNNHYIKTSEPEYVAKHLEWHFENQGINKATGPALAEVVKLVGERCNTLVELAQQSRYFYEDFAEFDADAAKKHLRGVAKEPLMLALSKIEALTEWNTEALHHVIAQVCEELEIGMGKIGMPLRVAVTGGGQSPSVDAVMNLIGQERVIARIKMALEYIETREANA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_CERS5
Sequence: MAQISLTFPDGNAREFPAGITPAEVAASISTSLGKKAISASVDGRHYDLQWPIEADAKIAIHTMADEAQALELIRHDLAHIMARAVQELWPDVKVTIGPVVANGWYYDFDREETFTPEDLGAIEKRMKEIINARDAVRTETWDRDRAIAHYEARGENFKVELVQAIPADQQIRMYWHGNWQDLCRGPHLQHTGQVPADAFQLMSVAGAYWRGDSNNKQLQRIYGVAFKTRDELKAYLHMLEEAAKRDHRKLGKEMELFHLQEEAPGMVFWHPNGWQIYRTLEDYMRGRLRKAGYKEIRTPQVVDRKLWEASGHWEAYKENMFLVEVEEEHAKEKRINALKPMNCPCHVQVYNQGLKSYRDLPLRLAEFGSCHRYESSGSMHGLMRVRGFVQDDAHIFCTEDQIEGECAAFIELLSSVYKDLGFDSFEIKLSTRPEVRIGSDEAWDKVETALENAIKKVGAAYEIDPGEGAFYGPKLDFKLTDAIGRKWQCGTFQVDPNLPTRLGAEYIGEDGAKHRPYMLHRAILGSFERFIGILIENYAGKLPFWLAPRQVVVASIVSDADPYVAEVVAALRARGVRAEADTRNEKINYKVREHSVGKVPVILAIGMQEVEGRTVSVRRLGETGTESAPLDQVVERLATDARIPG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_NEOYE
Sequence: MAKIQAIRGTKDILPDEIQYWQFIHNKISKLLECANYQEIRTPIFENSELYDRGIGEDTDIVNKEMYRFHDRSNRDITLRPEGTAGIVRSFIENKMSYHHSLQRLWYSGPMFRYERPQSGRQRQFHQLGIEFIGSLDARADSEVIHLAMSIFNNLNLHNLKLDLNSIGKVEDRSIYQVKLRDYLTKYHDDLDTDSQKRLTSNPIRILDSKDSNTQKILTEAPKISDFLSLESQQHFGDVCNYLKLLNIPYNINNKLVRGLDYYNDTAFEIKTLTSKGQDTICGGGRYDSLVHQLGGKATPAVGCAIGLERLLLIAKDNIDLPNKSIDFYIATQGTKANETGMQIMRFLHQQFFKIEIDVSSSNFSKQIKQANKKRAVACIIIGSNEIAEGIITIKWLFSQKQENITVVQLKHSVSYLKKKILFYKSSKNY
What are the official names of this protein?
Histidine--tRNA ligase, chloroplastic, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL11_METBU
Sequence: MASVVEALIPGGKANPGPPLGPALGPLGVNIKDVIEKINEKTKDYNGMQVPVKVIVNDDKSVEIEVGTPPTSALILKELNIEKGSGESGTVVVGNLEIAQVAKIARMKKDDILSYSLKAAIKEVMGTCVPMGVTIENLDPRECQKAVDEGKFDESLTAEAW
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SPEE_COREF
Sequence: MSGLEQPAELSRVWRWLLLVSVAICAASGLVYELALVSLSASLNGGGIVETSLIVAGYVAALGVGAILVKPFLRWPAQTFLAVETLLGLIGGLSALVLYMTFAVVGQNLWMLVLATALIGILVGAELPLLMTMIQRGRLADARTTGSLVATLNAADYLGALLGGLAWPFILLPWLGMMRGAAAAGMINLLAALFVGCVLLRHLLPRAQFIRAVVALLVAIAVLGTVLVRSDGIVATARQQLYRDPVIYAHQSDYQDIVVTQRGADRRLYLNGGLQYSTRDEHRYTESLVYPGLSDSARTALIIGGGDGLAARELLRFPDMRITQVELDPEVIEVANTILLPDNGGAMQDPRVTVITDDAFTWLRAGGDGGQRYDAIFVDLPDPNNDTMARLYSQEFYTLALARLNDGGRMVVQSSSAYTTPDVFWRIASTMSAAGCGAVIPYHVHVPTFGDWGFQLCGPEGTELGLRGDTPSLRFLTDEVLAAAGVFGADNQPRELEPSTLDHPRVVEDLRRGYRQAGE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ALR_RHORT
Sequence: MGHEDRATALLTVDLDAIADNWLALRGRLRPGASCAGVVKANAYGLGARKVVPALLAAGCRDFVVAQIDEGLDILDLLPADARLFVLSGPPEGAEDEVLDSALIPVLNSPDQIDRWAKACARAGRKAPAALHVDTGMRRLGLTPLELDALLADPRPLAAFTPVLVMTHLACADEPDHPLNAEQRALFAAAAARFPGLRASLANTSGIFLGPEWHFDLARPGIGLYGGNPTVGTANPMRQVVKLQGKILQVRRIDTPLSVGYGATHTAPAGSTIATVGVGYADGFPRSAGNRAMGLLAGRSVPVVGRVSMDLLTFDVSDVPENLARPGAMIDLLGPDLSVDALADRADTVSYEILTRLGARYPRRYGGVREGSGQ
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: CCA_SHEDO
Sequence: MKIYLVGGAVRDALLGLTIKDKDYLVVGSTPAEMLSLGYRQVGKDFPVFLHPKNQQEYALARIERKTGTGYDGFSCDANEHVSLEEDLLRRDLTINAIAQDEQGQLHDPYGGQQDIIHKQLRHVSQAFVEDPLRVLRVARFAARFHSLGFTVATETMALMSQISLSGELEHLTAERVWQECERALATDEPQVFFEVLAQCGALEVLFPEIHALFGVPQPEKWHPEIDTGKHTLLSLKQASLLTDDMAIRFATLVHDLGKALSPKESLPKHHGHGQKGLPLIKQFCQRLRVPNDYRDLALLVSDQHQNIHNAFELKASTLVSLFDKGDFWRKPERLNGLLSACIADIRGRTGLEKSAYPQAAYIEHCFQLAKQVEVQKIIADGFIGADIKNQLNRLRILAIDEYKQSLIKKQPN
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: APT_STRPN
Sequence: MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYATDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIGDYDYKVLMHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_KINRD
Sequence: MPRETGRKVIASNRKARHDYFIDDVYEAGVSLMGTEVKALRMGRASLVDGFAHIDRGEMWLEGVHIPEYVQGTWTNHTPRRKRKLLLHREEIDRWAGKVRESGLTIVPLALYFLDGRVKVEIGLARGKKNYDKRHALRERQDRREADRAMSERKDR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.