PharMolix/UniProtQA huggingface dataset:
Protein: NTPPB_DICDI
Sequence: MTSRPLILGSSSIWRKQVLIDMGYIFKTMSPDIDEKAIRDSDPKTLTLLISRAKAQALLKRIKESDDELDKKSIMICSDQVIVHNGVIREKPETEQQCREYLQSYEFHPAVAVVSVVVVNIETGKIVEGTDIATQHFKKISDEFIDKLIKQGDVMHCAGGFTVEHMADFTLQLEGEVETILGLPKTLTKNLISQVSQ
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase, Maf-like protein DDB_G0281937.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_HISS2
Sequence: MQYHDQSLQTLKLGKKTEYISTYDRTLLQAVPRKLNRDDLGISTKQPFSFGADIWTAYEISWLNLKGVPQVAIADVEIDYQSENLIESKSFKLYLNSFNQSQFENLQQVEQILQQDLIKCAKGQVKVRLNSLQNYAQQPIATLQGECIDEQDIEILCYEFDPNLLENCTNKQWVEEKLVSHLLKSNCLITNQPDWGTVQIHYIGNQINREKLLRYLISFRQHNEFHEQCVERIFCDLMKFAQPEKLSVYARYTRRGGLDINPFRSNFEPIPLNQRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_PSYWF
Sequence: MAYSYTEKKRIRKSFAELPHVMDIPYLLAIQVDSYEQFLQENKKPKARENTGLQAAFSSIFPIESNSNNAELQFVEYYLGAPEFDERECISRGSTFAAPLRVKIRLVIKDKDSKDKNSKAAIKDIREQNVYMGEIPLMTDNGTFIINGTERVIVSQLHRSPGVFFDHDKGKSHSSGKVLYNARIIPYRGSWLDFEFDAKDLVFARIDRRRKLLGTIILRALGMDTNEILDTFFEKVSVYKGEEQFEIDLVADRLRGEMAQFDIVSPDGEVLVEQGKRINARRIRQIEQSGMKKLAVPDEYLYERILAEDIVVNDEVIAKANTLIDHELLVKLSAFEASESIKEFKILFTNDIDHGTYIADTLRADSTGSREEALIEIYKVMRPGEPPTIDTAEKLFESMFFNADRYDLSNVGRMKFNRRLGRTFENTDDPDIKREQSVLTKDDIIDVLKELINIRNGIGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSSAESDNLSPQDLINSKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHNTHYGRVCPIETPEGPNIGLINSLATFAKTNEFGFLETPYRKVVDGKVTDDIEYLSAIEEVGTVIAQADSELDENGVLAEEMVMVRSGGESVRMPSDKVTHMDVSPSQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERHVARDSGVCVIARRGGVIEDVDASRIVVRVNEDEMQAGEAGIDIYNLIKYTRSNQNTCINQRIIVNQGDEIAGGDILADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILLSERVVKEDRFTTIHIQELTCVARDTKLGTEEITADIPNVGEAALSALDESGIVYIGAEVDAGDILVGKVTPKGETQLTPEEKLLRAIFGEKAADVKDTSLRVPTSTKGTVIDVQVFTRDGVEKDARAKSIEKSQLDNYRKDLKEELRIFEEAARSRISHLLDGQAISGGAGLKSGTVLAESELLEMSLETLLDIQPVEEEIAERLTQIQEFLVDKQKDIDTKFAEKKRKLTAGDDLAHGVQKIVKVYLAVKRRIQPGDKMAGRHGNKGVVSRIMPVEDMPYDENGNPVDIVLNPLGVPSRMNIGQVLETHLGMAAKGLGDKINGMIKAQAAVTELREFLDKIYNKVGGEQVDLDSLSDDDIRALAQNLRDGVPMGTAVFDGAREVQIDELLELAGYPSSGQQTLYDGRTGQKFDRPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGATYTLQEMLTVKSDDVEGRTRMYKNIVDGEQYMDPGMPESFNVLTKEIKSLGINIELKESN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL3_GEOTN
Sequence: MTKGILGRKIGMTQVFAENGDLIPVTVIEATPNVVLQKKTIENDGYEAIQLGFEDLSTKRANKPQIGHAAKANTAPKRFIREIRGANVNEYEVGQEVKVDIFSEGDIVDVTGISKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGAIAPNRVFKTKNLPGRMGGERVTIQNLKIVKVDPERNLLLIKGNVPGPRKGLVIVKSAVKAKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PARI_MOUSE
Sequence: MAVLNQLPVLGMIKEFRRSWRALCSSERTTLCGPDSMLLALQLSMAENNKQHRGEFTVCLSDVLLTWKYFLHEKLNLPIENMKVVEHYEDIKKTYDDFLKNSNTLDLIDVYKKCSSLTSNYENNMISPIQLRDFLSGTEYAVSDEANPHMPESPVKCSQNDEQVRVLVKKIFFSYLSLLVNSKNDLALASILNIPDRGLGREAFTNLKHAAREKQLSMFLMATSFIRTLELGGKGYAPSPSDPLWAHVKGLSEFINFIDKLDEILGKIPNPSLAGSRILSAIKMQLIKGHSSGEPFYKAVEEVVQDLNLRIKNIINSQEGVAVSANNISPVPPKSFAINHDTAYCGRDAVKILLVLLDEDAASAPTRNKAELLYNDESTVPHSGPSVLTLFRSPTQEKNTSVKPLRERIHKSLQTEKNKMWQTLIRSQFACTYKDDCIMSKNKWHVNSSSKPLSALHLEDDVSEGAQSSVGKARIEASSENAHVGRWKGDKLPRKSTQRQISKGKQLDLDSENLHCDRGNELYQHKNIKIPKVPSGSHSKAGGKLAQGTKGNRCPARGKLIPGQTKLTQFFML
What is the function of this protein?
Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability.  Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure.  Binds single-strand DNA and poly(A) homopolymers.  Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect (By similarity).
What are the official names of this protein?
PCNA-interacting partner, PARI, PARP-1 binding protein, PARP1-binding protein, PARPBP.
What is the protein family that this protein belongs to?
Belongs to the PARI family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to chromatin in response to S phase arrest but not in mitosis. Targeted to chromatin via its interaction with PCNA (By similarity).
Protein: RS8_PSYA2
Sequence: MSMQDTVGDMLTRIRNAQMANKVSVAMPSSKLRKSIADLLVNEGYVASAVVTEENNNKATLTIVLKYFEGKAVIETIQRFSRPGLRQHRGKDAIPTVKQGMGVAIVSTSQGIMSDRAARAAGIGGEIVAFVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SYR_BURL3
Sequence: MLPAHKQTLEALLADSVKQVAHALKGADAATVAPVITLERPKVAAHGDVACNVAMQLAKPLGTNPRQLAEQIVAALTAQPGAQGLVEAAEIAGPGFINLRLSAAAKQAVIAAVFDQGRAFGTSDREKGKQVLLEFVSANPTGPLHVGHGRQAALGDVLANVIASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDFLNGETVAASDGEPVKGTGDVEDLDAIRKFAVTYLRREQDMDLQAFGVKFDQYYLESSLYSEGRVEKTVDALIKAGMTYEQDGALWLRTTDEGDDKDRVMRKSDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTIARVRAGLQGLHIGIPKGYPDYVLHKMVTVMREGQEVKISKRAGSYVTVRDLIEWSGGAAAGQEAAPDLIDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARICSVLNELKSRYNVDVAQLPGADLSQLTSAQAASLMQKLAEYPDMLTHAANELAPHAVAFYLRDLAGEFHSFYNAERVLVDDEAPRNARAALLAATRQVLENGLAVLGVSAPAKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_SHEON
Sequence: MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSVVANATTNHSADVPEADTGVPAAVAATQNLITVKTDQLDVQINPVGGDIVYAALVSHKLEQGKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAIFAASKTEFTLADGQDSLEVPLTYVAENGVTYTKVFVFHRGKFNVNIDYKINNTSAAPLQVQMYGQIKQTIKPSESSMMMPTYRGAAFSTASVRYEKYNFEDMGKNNLNQPTIGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDVAPGATQEISSQFYVGPKDQKALSALSDTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGVAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLQDLKERFGDDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFIMQKMQPIAPTMDPMQVKMMQWMPVIFTVFFLWFPSGLVLYWLVGNIVAIIQQKIIYAGLEKKGLN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COXZ_RHOPB
Sequence: MTEQPTNRNDVPRRGLGRDATVASICGLVVALMVGASYAAVPFYNWFCRATGFNGTTQVATAAPIAAPLPRKITVRFDSNVNGLPWKFTPEQTEIEIPIGQVVTVFYTVTNLSAHETTGQAAYNVAPLTVGAYFQKINCFCFTEQTFAAGETREMPVVFYVDPALAADPENDGLNSITLSYTFYPVRAPTPKPVAAGEPDSRKGAL
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: TRXB_HELPJ
Sequence: MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFMQPWQEQCFRFGLKHEMTAIQRVSKKGSHFVILAEDGKTFEAKSVIIATGGSPKRTGIKGESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAIYLANICKKVYLIHRRDGFRCAPITLEHAKNNSKIEFLTPYVVEEIKGDASGVSSLSIKNTATNEKRELVVPGLFIFVGYDVNNAVLKQEDNSMLCECDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATAALSVISYLEHH
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL22_ORYSJ
Sequence: MAAVGACFLQQLAVVALLALWCSHGAIASDPGLLQDFCVVDKMSQVRVNGFPCKDAKDVVAGDFFFSGLHMAGNTTNKQGSNVTTVNVAQIPGLNTMGVSLVRIDYAPNGLNPPHTHPRATEIPTVLEGSLYVGFVISNPENKLFTKVLNKGDVFVFPQGLVHFQFNNGTNNAVALAALSSQNPGVITVGNAVFGSKPSISDDILAKAFQVDKNIIDRIQAQF
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Putative germin-like protein 2-2.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: FKBP6_DICDI
Sequence: MNLSLPLNKDNSGNSGNSGNSGGSVCSSNNTLSPILSNSILSSPISSPRLISSSNNNNNNNNNNNNNNNNNNNNNNNNTINSDSNNNNNINNKPRKAGIQLDSDGCLIKRIIKEGYGEIPPPRSIVTVHYEGYLSNQVLFDSSVQRNSPFTFQMGTKSVIDAIELSISTMKVGQEAEIVTTQRYAFGKLGLPPFIPPNVSVIYKIKLLSYKLKSNDFTNFESLINKSKEEKEIGNQFFQKSNYKKSIRHYVKSIWILNDPEQTLGLNEMENKLLKDTLIILYLNLASCNIKLKDGKRGISNCEKILELGGNTTAKFYYRMGQAYSLNKQYDSAKRCLVQAIRLEPNDKLLRDELENIKKLQEENNK
What is the function of this protein?
PPIases accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
FK506-binding protein 6, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: LOLD_NITWN
Sequence: MEQGKKETPTVYLHDIKREYTQGETRLTILDSTKLALWAGQSVALVAPSGSGKSTLLHIAGLLESPDAGEVYIGGIATSGLSDVERTQIRRTDIGFVYQSHRLLPEFTALENVMLPQMIRGLKRAETVKRAQEILAYLGLEDRVTHRPAELSGGEQQRVAIARAVANAPRVLLADEPTGNLDPQTADHVFNALMQLVKATRVSMLIATHNMELADRMDRRVSLENGHVVELD
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ASSY_DECAR
Sequence: MSDIKKVVLAYSGGLDTSVILKWLQDVYKCEVVTFTADLGQGEELEPARAKALKAGIKPKNIYIDDVREEFVRDFVFPMFRANTVYEGEYLLGTSIARPLIAKRLIEIVNETGADAICHGATGKGNDQVRFELGAYALKPGIKVIAPWREWDLMSREKLMAYAEKHGIEIDMKHKKGGSPYSMDANLLHISYEGRHLEDPAAEAEESMWRWTVSPEKAPNKAEYLDLEFAKGDVVAVNGKKLKAHEVLALLNELGGKHGIGRLDLVENRYVGMKSRGCYETPGGTILLRAHRAIESVTLDREVAHLKDDLMPRYASLVYNGYWWSPERKALQVLIDHTQQTVNGVVRLKLYKGNVIVVGRDSKTDSLFDSTIATFEDDAGAYDQRDAGGFIKLNALRLRIAANLAGRKAGKPVAKKAAAKPVTKAVPKAVAKPVTKAVAKAAEKPVAAKATAKPVKAPVKKPIAKKKG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_BACVZ
Sequence: MKHRYLPATEQDKKEMLKAIGAETIDELFADIPENVRFQKDYQIKKAKSETELTRELTKLAAKNKDAVTYASFLGAGVYDHYQPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDIANSSMYDGGTALAEAAMLASGHTKKKKIVISAAVHPESRDVLKTYAKGQYIEVVEVPAKNGVTDLEALEHAVCDETAAVIVQYPNFFGQIEPLKDIEPLAHKGNSQLIVSSNPLALGILTPPGAYGADIVVGDAQPFGIPAAFGGPHCGYFAVTKKLMRKVPGRLVGQTEDENGRRGFVLTLQAREQHIRRDKATSNICSNQALNALAASAAMTALGKNGVKDMARQNILKADYARRQAEKAGLHVAFDGPIFNEFAVRLNLPVKEANRRLLQDGIIGGYDLGLAYPELNQHMLIAVTELRTKEKIDSLIARLGDQHE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: UGTP_STAA9
Sequence: MVTQNKKILIITGSFGNGHMQVTQSIVNQLNDMNLDHLSVIEHDLFMEAHPILTSICKKWYINSFKYFRNMYKGFYYSRPDKLDKCFYKYYGLNKLINLLIKEKPDLILLTFPTPVMSVLTEQFNINIPVATVMTDYRLHKNWITPYSTRYYVATKETKQDFIDVGIDPSTVKVTGIPIDNKFETPINQKQWLIDNNLDPDKQTILMSAGAFGVSKGFDTMITDILAKSANAQVVMICGKSKELKRSLIAKFKSNENVLILGYTKHMNEWMASSQLMITKPGGITITEGFARCIPMIFLNPAPGQELENALYFEEKGFGKIADTPEEAIKIVASLTNGNEQLTNMISTMEQDKIKYATQTICRDLLDLIGHSSQPQEIYGKVPLYARFFVK
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer two glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PH2AB_DICDI
Sequence: MTEPLDWRFSQTFGGKGNEDASDANVVPAIEFDQTGDFIAVGDKGGKVLLLKRTHDKQSSKKSKLPEYRFYSEFQSHEPEFDYLKSLEIEEKINKIKWCPKQNDAQFLLTTNDKTIKLWKVYEKKIKQVSTSATTTGPSYNGSLASNNTRSPSHTTYIYNSSGAHNMNNNMNNSNNNNNLNNFKIPKLTTRETVVTATPRKIFQNAHAYHINSISLNSDGETYISSDDLRIHLWNLNINTECFNVVDIKPTNMEDLTEVITSAEFHPTSCNIFMYSSSKGTIKLGDLRSSALCDNHAKVFEEYEDPSNKSFFSEIISSISDIKFSRDGRYILSRDFLTLKLWDINMENKPVKTIQIHDYLKPKLCDLYENDCIFDKFECTLNHDGTQMLTGSYHNYLHIYDRNSKQDVCLEASKQATKSKTKTLTTKMKLRSSKKEPKKPEDIHPDAIEYTKKTLHCAWHPKDNLIAVGAANTVYLYAATENK
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A regulatory subunit phr2AB, Protein phosphatase 2A 55 kDa regulatory subunit, Protein phosphatase 2A B55 regulatory subunit, Protein phosphatase 2A PR55 regulatory subunit, Protein phosphatase 2A regulatory B subunit.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: RS2_STAS1
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQKTVKKVEEAYNFIKQVSEDGGKVLFVGTKKQAQDSVKAEAERAGQFYVNQRWLGGILTNYKTISKRIKRISEIEKMEEDGLFEVLPKKEVVELKKEYDRLIKFLGGIRDMKSMPQALFVVDPRKERNAIAEARKLHIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTGKMADAILEGQQGVSNEEVAAEQNIDLDESKEATEAETTEENTSVESN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NMDZ1_HUMAN
Sequence: MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES
What is the function of this protein?
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280).  Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761).
What are the official names of this protein?
Glutamate receptor ionotropic, NMDA 1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities.
Protein: URIC1_CANLI
Sequence: MAKEIVGGFKFDQRHGKERVQVARVWKTKQGWYFIVEWRVGNSLLSDCVNSYVRDDNSDIVATDTMKNTVYAKAKECSEILSVEDFAILLAKHFISFYKQVTAAIVNIVEKPWERVSVDGQPHEHGFKLGSERHTAEAIVQKSGALQLTSGIEGLSLLKTTKSGFEGFIRDKYTALPETHERMLATEVTALWRYSYESLYSIPQKPLYFTDKYLEVKKVLADNFFGPPNVGVYSPSVQNTLYLMAKAALNRFPEIASIQLKMPNIHFLPVNISNKDGPIVKFEADVYLPTDEPHGSIQASLRRLWSKL
What is the function of this protein?
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
What are the official names of this protein?
Uricase-2 isozyme 1, Urate oxidase, Uricase II clone pcClNUO-01.
What is the protein family that this protein belongs to?
Belongs to the uricase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: YOPJ_YERPU
Sequence: MIGPISQINISGGLSEKETSSLISNEELKNIITQLETDISDGSWFHKNYSRMDVEVMPALVIQANNKYPEMNLNLVTSPLDLSIEIKNVIENGVRSSRFIINMGEGGIHFSVIDYKHINGKTSLILFEPANFNSMGPAMLAIRTKTAIERYQLPDCHFSMVEMDIQRSSSECGIFSFALAKKLYIERDSLLKIHEDNIKGILSDGENPLPHDKLDPYLPVTFYKHTQGKKRLNEYLNTNPQGVGTVVNKKNETIVNRFDNNKSIVDGKELSVSVHKKRIAEYKTLLKV
What is the function of this protein?
Serine/threonine-protein acetyltransferase translocated into infected cells, which inhibits the host immune response and induces cell death by mediating acetylation of target proteins (PubMed:10489373, PubMed:12433923, PubMed:16728640, PubMed:22563435, PubMed:26810037).  Inhibits the MAPK and NF-kappa-B signaling pathways by acetylating protein-kinases such as MAP2K1, MAP2K6, MAP3K7/TAK1 and I-kappa-B kinase (CHUK/IKKA and IKBKB) on serine and threonine residues critical for their activation by phosphorylation, thereby preventing protein-kinase activation (PubMed:16728640, Ref. 9, PubMed:30361383).  Promotes pyroptosis, a programmed cell death, in host cells by mediating acetylation of MAP3K7/TAK1: MAP3K7/TAK1 inactivation triggers activation of caspase-8 (CASP8), followed by CASP8-dependent cleavage of gasdermin-D (GSDMD) and induction of pyroptosis (PubMed:30381458, PubMed:30361383).  Also able to induce intestinal barrier dysfunction by acetylating and inhibiting host protein-kinases RIPK2/RICK and MAP3K7/TAK1, thereby promoting cell death (By similarity).
What are the official names of this protein?
Serine/threonine-protein acetyltransferase YopJ, Virulence factor YopJ.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase YopJ family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (TTSS).
Protein: QUEA_BACCR
Sequence: MDINLFDFHLPEELIAQVPLEDRETSRLMVLDRETGDIEHKHFTDILSYLHEGDCLVLNETKVMPARLHGVKEDTGAHIEVLLLKQEEGDKWETLVKPAKRVKEGTVISFGEGKLKATCTGTADQGGRQLEFSYDGIFYEILDELGEMPLPPYIKETLEDRDRYQTVYAKEIGSAAAPTAGLHFTEELLEKLKQKGVQLAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAALLNRVKQNGGRIITVGTTSTRTLETIATDHDGKLCAASGWTDIFMYPGYEFKAIDGLITNFHLPKSTLIMLVSAFANRDNVLHAYNEAVKEKYRFFSFGDAMFVASHAKMRNK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y151_UREPA
Sequence: MKNQNEKQIKEYVNKFKDLRNQLTKNNDVKKVCDLINDLFFEVYKNNLIDEVIKEINKHD
What are the official names of this protein?
Uncharacterized protein UU151.