PharMolix/UniProtQA huggingface dataset:
Protein: PSBC_OEDCA
Sequence: METLYNGTLTLGGKDQESTGFAWWAGNARLINLSGRLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGYGVGPGGEIIDTFPYFVSGVLHLISSAVLGFGGVYHSLIGPETLEETFPFFGYVWKDKNKMTNILGAHLIILGIGAWLLVWKALYFGGVYDTWAPGGGDVRIITNPTTNPSVIFGYLLKSPFGGDGWIVSVDNMEDIIGGHIYIGTINILGGLWHVFTQPWAWTRRAFVWSGEAYLSYSLAAISVMGFVACCMSWFNNTAYPSEFYGPTGPEASQSQAFTFLVRDQRLGANVASAQGPTGLGKYLMRSPTGEIIFGGETMRFWDFRGPWLEPLRGPNGLDLNKLKNDIQPWQERRAAEYMTHAPLGSLNSVGGVATEINATNFVSPRSWLATSHFCLGFFFFVAHLWHAGRARAAAAGFEKGIDRFNEPTLSLRPLD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ODPA1_ARATH
Sequence: MALSRLSSRSNIITRPFSAAFSRLISTDTTPITIETSLPFTAHLCDPPSRSVESSSQELLDFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLGRGGSLHEVFSELMGRQAGCSKGKGGSMHFYKKESSFYGGHGIVGAQVPLGCGIAFAQKYNKEEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKQHALEKGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVDDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGPDRKEVKASLP
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha-1, mitochondrial, PDHE1-A.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FLDB_CLOSG
Sequence: MSDRNKEVKEKKAKHYLREITAKHYKEALEAKERGEKVGWCASNFPQEIATTLGVKVVYPENHAAAVAARGNGQNMCEHAEAMGFSNDVCGYARVNLAVMDIGHSEDQPIPMPDFVLCCNNICNQMIKWYEHIAKTLDIPMILIDIPYNTENTVSQDRIKYIRAQFDDAIKQLEEITGKKWDENKFEEVMKISQESAKQWLRAASYAKYKPSPFSGFDLFNHMAVAVCARGTQEAADAFKMLADEYEENVKTGKSTYRGEEKQRILFEGIACWPYLRHKLTKLSEYGMNVTATVYAEAFGVIYENMDELMAAYNKVPNSISFENALKMRLNAVTSTNTEGAVIHINRSCKLWSGFLYELARRLEKETGIPVVSFDGDQADPRNFSEAQYDTRIQGLNEVMVAKKEAE
What is the function of this protein?
Component of the phenyllactate dehydratase complex FldABC that is involved in the fermentation of L-phenylalanine via a Stickland reaction.  This complex catalyzes the reversible syn-dehydration of (R)-phenyllactate to (E)-cinnamate in two steps, a CoA-transfer from cinnamoyl-CoA to phenyllactate, catalyzed by FldA, followed by the dehydration of phenyllactyl-CoA to cinnamoyl-CoA, catalyzed by FldB and FldC.  Requires the activator FldI to initiate catalysis.
What are the official names of this protein?
(R)-phenyllactyl-CoA dehydratase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the FldB/FldC dehydratase alpha/beta subunit family.
Protein: RS15_SALEP
Sequence: MSLSTEATAKIVSEFGRDANDTGSTDVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: H2B_DROOR
Sequence: MPPKTSGKAAKKAGKAQKNITKTDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CRCB2_SYMTH
Sequence: MAGVAAGGALGAWARHGLGSWLTALLPSTFPLPTLMINVLGALLLGFVAGYGIERGRLPEAWRLPVTVGFIGSFTTFSTWSVDTVLLLDAGRWPLALANVGISLAVGLAAVWVGRRLAFRWRV
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLUC1_ONCMY
Sequence: MFGIHSLAGVLLLVIVQRQLASPLQEAEDNSSLETTDPLLEDLMGVSNVKRHSEGTFSNDYSKYQEERMAQDFVQWLMNSKRSGAPSKRHADGTYTSDVSTYLQDQAAKDFVSWLKSGRARRESAEESRNGPMSRRHVDGSFTSDVNKVLDSLAAKEYLLWVMTSKTSGKSNKRQEDH
What is the function of this protein?
Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level.
What are the official names of this protein?
Glucagon-1, Glucagon I.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_DROPE
Sequence: MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLSIVDVDPETGRQTDGSKTYAICGEIRRMGESDDCIVRLAKKDGLITKNF
What is the function of this protein?
May be an associated component of the ribosome rather than a core structural subunit.  May act as a translation initiation factor.  Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva (By similarity).
What are the official names of this protein?
40S ribosomal protein S21, Overgrown hematopoietic organs at 23B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: DCD_SALAR
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTYESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: DHX40_RAT
Sequence: MSRFPAVAGRAPRRQEEGERPVELQEERPSAVRIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLNKFSVIILDEAHERTLTTDILFGLLKKLFQDKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTASGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIRAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQKHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHELNAHDLSSVARREMRDDARRKWTNKENVKQLKDGISKEVLKKMQRRNDDKSISDARARFLERKQQRIQDHSDTLKETG
What is the function of this protein?
Probable ATP-dependent RNA helicase.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DHX40, DEAH box protein 40.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
Protein: QUEC_OCEIH
Sequence: MTGKKAVVILSGGLDSTTCMGVGKEAGYELYPISFHYGQRHDREIENAKKVASYFNVTEHKVFSLEFLKEIGGSSLTDQSMEVSQEGVGEDVPNTYVPGRNTIFLSIAASYAEAIGAEKIYVGVSAVDYSGYPDCRPEFIEAMQQTIYQGTNANPAMTIEAPLIDLSKGDTVKLGMKLNVPYHLTTSCYLGGEEACGECDSCRLRLQGFEEAGATDPIKYM
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: COXX_GRAFK
Sequence: MSNTRVHNPSASILSDFKEITKMRLAISVVFSSVAGYFLGADTIDFVTVTLLAIGGYLMVGASNAYNQIIERNLDALMDRTKNRPLPAGRMSVPVAFTIASAFTVLGLVVLYVINPKTAMFGAISIFLYVSIYTPLKTKTPLSVFVGAFPGAIPFMLGWVAASGSFSIEPGTLFMIQFFWQFPHFWAIGWWLFDDYKKGGFFMLPTGKRDRGTAIQIILYTCWTILVSLIPVFGVTGKLMLTPVSGIIIFLLGLGMLYYAIRLFKEKTAEAAKKLMFASVSYITLLQIVYVLDKFIREWI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL34_METEP
Sequence: MKRTYQPSKLVRKRRHGFRARMATAGGRKVIAARRAHGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SNTAN_BOVIN
Sequence: MCGCVHSTQDQALRLEGEPNPPAAPTSTLAPKNMPKSISISKQLASIKALRKGSDLEKAIATAALVFRNSSDPDGKLRKATAKNLLQTQFKNFAEGQETKARYKDLLSELDEHTENKLDFEDFMVLLLSVTIMSDLLQNIWSVKITQ
What is the function of this protein?
May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules.
What are the official names of this protein?
Sentan, Protein S100-A1-like, S100 calcium-binding protein A1-like.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Expressed exclusively at the cilium tip where it localizes between the cell membrane and peripheral A-subfibers.
Protein: MATK_PRUDU
Sequence: MEEFQGYLELDRYQQHDFLYPLIFREYIYALAHDHGLNRSILLDNVGYDNKSSLLIIKRLISRMYKQNHFFISANDSNQKKKLGYNKNLYSQKISEGFTVIVEISFSLQLVSSLEATKTVKSYNLRSIHSIFPFLEDKFPHLNYVSDVLIPYPIHLEILVQTLRYWVKDASSLHLLRLFLHEYYNWNSLITSNNFFFSKSNPRLFLLLYNSHVCEYEFILLFLRNQSSHLQLTSSGIFFERIHFYEKIKYPVEEVFANDFPASILWFFKDPFMHYVRYQGKSILASKDTPLLMNKWKYYLVNLWQCHSYVWSQPGRIYINKLSKHSLDFLGYFSSIRPNLSVVRSQMLENSFITDNAMKKLDTLVPIIPLIGSLAKVKFCNALGHPISKSTWADSSDFDIIDRFLRICRNLSHYYSGSSRKKSLYRIKYILRLSCLKTLARKHKSTVRTFLKRLGSKLLEEFFTEEEQILSLVFPRASYTFTFKKFYRGRIWYLDIFCINDLINYE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURI_KLEP3
Sequence: MATNLQDGNTPCLAATPSDPRPTVLVFDSGVGGLSVYNEIRQLLPNLHYIYAFDNVAFPYGEKSEEFIVERVVEIVTAVQQRYPLALAVIACNTASTVSLPALREKFAFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRPYTRELIDRFANECRIEMLGSAELVELAEAKLHGEPVPLEELRRILRPWLRMQEPPDTVVLGCTHFPLLQEELQRVLPEGTRLIDSGAAIARRTAWLLEHEAPDAKSSDENKAFCMALTAETEQLLPVLHRYGFPTLEKLPL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: MDM32_VANPO
Sequence: MAGLLPRAYGGVLRRSYIYLGSQCSNSVSRLTVGSTFRLVRMKSWGTSKFHTNGSPVLNEIKKISKSNGITIINPLVNKVTTNNVSTSSNGKAAVAAATAATAVSLGSTGQDDALSRNTDFLHIQNILLQKNQDRMNKQKLLSEATNFYERFKINTKWLLIRGNRPFSADEIGTLFSWIILSQILWIILGTTTFVSILLIIFNTVFAKEMVGNVVGKLLNIFLDGIDVKFQDALVPEWRKGCIRFNNVQLRTHPLQASEPENINDYNELVNNMIEFDLKLHQIELSLSLKKWLLGNGLIQDLTIMGMRGNITVTPVSLENKIDDNQRVNLIDWFSNPYYHLGNVKVTDSSIILHDNQLSKDFKVSIYNLDMPQLRFQWIINDFLSSNVVDGSINHSLFNIHKRQHKLAYIKDLENDLSDWKRITRIRLDSIDVKKLGLNNSNAFNWMDDGQLDIIADVMLPNEQENEPDFDFTRNKKEHMSKSNNKYVVLDLKFRFKDLKAIFPDRAPRLSNGEEILSLDELKQIILFINRKYDLYHSYANSSYKNTLWDAPNIAINKAKSFPVTTVFQSKKDFSNEDSDEEDRKLKKQIIRFHDDISTPNNELVLSCKVVKNINELKNMVLFWETGIYDSLSMELYIDLMKMVEEWEYKKKTNWMTDWGSSVASQLIIVGFGAMV
What is the function of this protein?
Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria.  Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures (By similarity).
What are the official names of this protein?
Mitochondrial distribution and morphology protein 32.
What is the protein family that this protein belongs to?
Belongs to the MDM31/MDM32 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NSA1_YEAST
Sequence: MRLLVSCVDSGSIKEVLCNIGTDTSVQSALQPFHVAPHLAEGLKAYVDRMWVISEDEAILARNSGVVELVKISKHLKENEALQVDPKGESKNEKSLSDDLPKFDISEFEITSSVSDLFDDAKLESLSSKSVKRTKLVDGFVTLCPIKKDSSNNTFVAATKSGLLHIIKKGEDKKLIKLASLGLKAPVEFLQLYDLEDTDTDKYIFAYGGEENLIKLVEIDSSFQSLKQIWEAKNVKNDRLDMRVPVWPMALRFLEPSPGKTEKGKLNYQFAAITRWSHLTKYSTQHGRKPFAQIDLLPNREPLSQMEVFDAKGENVVSSLGNFQSETFNELNVITTDYKKNVFKFDGNGRMLGKVGRDDITGSSTYIHVHDGKYLLQGGLDRYVRIFDIKTNKMLVKVYVGSRINFIVMLDDVEIEMPLSPSAKAAKGKQKRKVTELEEDADELWNKLEGKVAASKASKKSKI
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein NSA1, NOP7-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the NSA1 family.
Protein: INP1_KLULA
Sequence: MAIMGSPKKKSSGPFQSLKNSFLRNKGQPPQLQPWNPQVRTDNTKRKSVQRTTLFRHDYVKVRSWPSDNPKNINVILSKTSFEIYEIDMGNSKERMNYLSLGKKDQFVHPILPKLKVGRVPSDQKQEFKIIISLFNPERFWEVTFLSINHGRVPRKVINDLEQVLSKICQYNNKDPDNASLKDTKNDTKAIPSPKIDILEEVDDLEYLLAENVPDQEQIPEAESLELNESSTISSISMEHSLVQSGDVVNKTFKQALGRIKPIDFNTRAESSRYKRFSSFHSAFLDVPRISAEYQHSLQDKRRSISVPTAIDYKSVSNHDMRKGVDFDKVSWMDVTFEDFPEI
What is the function of this protein?
Required for peroxisome inheritance.
What are the official names of this protein?
Inheritance of peroxisomes protein 1.
What is the protein family that this protein belongs to?
Belongs to the INP1 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Peripheral membrane protein.
Protein: DPH5_ASPFU
Sequence: MLYLVGLGLADETDITVKGLEVVKRAERVYLEAYTSILLVSKEKLEAFYGRPVIEADRELVETGSDEILAGADKADVAFLVVGDPFGATTHTDLVLRAREMGIESKVIPNASIMSGIGCTGLQLYNFGQTVSMVFFTENWKPTSYYDRVKENVQLGLHTLVLLDIKVKEQSYENMARGRRIFEPPRYMTVAQCASQMLETEEERKEGVFGPDSLAVGAARVGGPDQKLVVGTLKELSEVDMGPPLHSLVLLGRKAHDLERLYIREFAVDKATFDASWNKGYGATS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester.  The four successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine methyl ester synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_CAUSK
Sequence: MSKIIGIDLGTTNSCVAIMDGKTPKVIENAEGARTTPSVVAFLEDGERLVGQPAKRQAVTNPTNTLFAIKRLIGRNFADPVVAKDKAMVPYEIVKGPTGDAWVKAHGKDYSPQEVSAFILQKMKEAAESHLGEPVTKAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLEMNEGKKIAVYDLGGGTFDVSVLEIGDGVFEVKSTNGDTFLGGEDFDLRIVDYLADEFKKEQGVDLRKDKLALQRLREEAEKAKKELSSTAQYEVNLPFISMNASGPLHLNIKLSRSKLEALVEDLITRTIGPCEQALKDAGLKKSDIDEVILVGGMSRMPKVQQAVQDFFGREPHKGVNPDEVVALGAAVQAGVLQGDVKDVLLLDVTPLTLGIETLGGVFTPLIERNTTIPTKRSQTFSTADDNQSAVTIRAFQGERPMAVDNKFLGQFDLQGIPPAPRGVPQIEVTFDIDANGIVNVHAKDKATNKEHSIRIQANGGLSDADIERMVKEAEANKASDEKKKALVEAKNQGEAIVHSTEKAFAEHGDKIGGAEKTAIETGLTDLKAALEGEDVEAIQAKTQALIQASMKLGEAMYGAQQGADGGEEAAHDDGVVDAEFEEVDDSKPSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS15_CLOP1
Sequence: MDKIRKQEIIAKHARHEGDTGSPEVQIALLTERINSLTDHLRTHKKDHHSRRGLLMMVGQRRGLLNYLYEQDIERYRAIIKELGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GRIK1_MACFA
Sequence: MELGTLLAQPGLWTRDTSWALLYFLCYILPQTAPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQTHPTNSTSGTTLSTDLECGKLIREERGIRKQSSVHTV
What is the function of this protein?
Ionotropic glutamate receptor.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.  The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.  May be involved in the transmission of light information from the retina to the hypothalamus (By similarity).
What are the official names of this protein?
Glutamate receptor ionotropic, kainate 1, GluK1, Glutamate receptor 5, GluR-5, GluR5.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: SCUB3_MOUSE
Sequence: MGSGRVPGLCLLLLLVHARAAQHGKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCRDGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHVKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCSCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERSCQDIDECSFDRTCDHMCVNTPGSFQCLCHRGYLLYGVTHCGDVDECSINKGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPVKCQSSLGASKAMLSCNRSGKKDTCALTCPSRARFLPESENGFTVSCGTPSPKAAPARVIHSGNSTVSSSCHEAAVLPVKQRASFKIKDAKCRLHLRNKGKAEEASRILGPGSVPCSDCLVTFIHLKCDSSRKGKGRRARTPPGKEVTRLTLELEAEVRAEETTAGCGLPCLRQRMERRLKGSLKMLRKSINQDRFLLRLAGLDYELAHKPGLGAGDRAELVEVCRPGQHRAGTKCVSCPQGTYYHGQTEQCVPCPAGTFQEREGQLSCDLCPGSDAHGPLGATNVTTCAGQCPPGHHSGDGFKPCQPCPRGTYQPEAGRTLCFPCGGGLTTKHEGAVSFQDCDTKVQCSPGHYYNTSIHRCIRCAVGSYQPDFRQNFCTRCPGNTSTDFDGSTSVAQCKNRQCGGELGEFTGYIESPNYPGNYPAGVECVWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFEVLAHPQNYFKYTEKHKEMLPKSFIKLLRSKVSSFLRPYK
What is the function of this protein?
Is a positive regulator of the BMP signaling pathway, required for proper chondrogenesis, osteogenesis and skeletal development (PubMed:33308444).  It acts as coreceptor for BMP ligands, particularly BMP2 and BMP4, facilitating their interactions with BMP type I receptors (By similarity).  It is required for ligand-induced recruitment of BMP receptors to lipid rafts (PubMed:33308444).  Binds to TGFBR2 and activates TGFB signaling (By similarity).
What are the official names of this protein?
Signal peptide, CUB and EGF-like domain-containing protein 3.
What are the subcellular locations of this protein?
Secreted. Cell surface.
Protein: RR4_SORBI
Sequence: MSRYRGPRLKKIRRLGALPGLTRKTPKSGSNQKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKRSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSFRCKPRDIITTKDNQRSKRLVQNYIASSDPGKLPKHLTVDTLQYKGLVKKILDRKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUB2_CANGA
Sequence: MSHEGEEDLLEYSDNEQEIQVDNKETAVEGTTENEATQENGEADKKGSYVGIHSTGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQLDPVPGEVSVVVICNARELAYQIRNEYLRFSKYMPDVRTAVFYGGTPIAKDAELLKNKDTAPHIVVATPGRLKALVRDKMIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVIIFVKSTSRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVSTDVFGRGIDIERINLAINYDLLNEADQYLHRVGRAGRFGTKGLAISFVSNKEDEEVLSKIQERFDVKIAEFPEEGIDPSTYLNN
What is the function of this protein?
ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus.  SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly.  May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase SUB2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus.