PharMolix/UniProtQA huggingface dataset:
Protein: PIT1_HUMAN
Sequence: MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR
What is the function of this protein?
Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary.  Specifically binds to the consensus sequence 5'-TAAAT-3'.  Activates growth hormone and prolactin genes (PubMed:22010633, PubMed:26612202).
What are the official names of this protein?
Pituitary-specific positive transcription factor 1, PIT-1, Growth hormone factor 1, GHF-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCH2_CANLF
Sequence: MDEAVGDLKQALPCVAEAPTVHVEVHQRSCSTAKKEDIKLSVRKLLNRHNIVFGDYKWNEFDDPFLARNVQSVSIVDTELKVKDPQPIDLGACTIALHVFQLNEGGPSSETLEEETENITAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVDSNLIAWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYQYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHCNVVILTTSNITERIDVAFVDRADIRQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPTVTIEGFLQALSLAVDKQFEERKKLSSCI
What is the function of this protein?
Plays a key role in chromosome recombination and chromosome structure development during meiosis.  Required at early steps in meiotic recombination that leads to non-crossovers pathways.  Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.  Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation.  In males, required for efficient synapsis of the sex chromosomes and for sex body formation.  Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes.  Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity).
What are the official names of this protein?
Pachytene checkpoint protein 2 homolog, Thyroid hormone receptor interactor 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. PCH2 subfamily.
Protein: SYS_STRA1
Sequence: MLDLKRIRTDFDVVAKKLATRGVDQETLTTLKELDIKRRELLIKAEEAKAQRNVASAAIAQAKRNKENADEQIAAMQTLSADIKAIDAELADVDANLQSMVTVLPNTPADDVPLGADEDENVEVRRWGTPREFDFETKAHWDLGESLGILDWERGAKVTGSRFLFYKGLGARLERAIYSFMLDEHAKEGYTEVIPPYMVNHDSMFGTGQYPKFKEDTFELADSPFVLIPTAEVPLTNYYRDEIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLNLPYRVITLCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEVDGKVRLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEVLRPYMGNIDIIKPN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_HALWD
Sequence: MKTTGGSEEQKRRAGEKAVEYVNDGDIVGLGTGSTAAAAIDALGDAVAAGYDIHGVPTSFATRDRAIEAGIPLTRIEAVDHIDVAIDGSDEINNNLTLIKGGGAAHAREKVIDATADQFIVVADESKLVETLSEPVPVSTLPMAQKPVKHRLDSLGATTTLRSATMKDGPVITDNGNIVFDCAFGHIENAEALAKSLAEIPGTVAHGLFVNLADVACIGTENGTNVYHGDQDQGQN
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MURC_CHLPD
Sequence: MELGKTKSVHIVGIGGAGMSAIAELLLTSGFGVTGSDLSSGEVTERLSERGAVIYQGHKAEQVGESDVVVYSSAIRPAENVEIVAAEQAGIPVIKRDEMLGELMRYNYGVCVSGTHGKTTTTAMIATMLIEAGESPTVMIGGVSDYLKGSTVVGSGKYLVIEADEFDRAFLKLTPTIAVINSLESEHMDTYGTIEELRKAFIAFANKVPFYGRVICCVDWPEIRKLIPHLNRRYTTFGIDEPADVMASDMVMDKNRSRFTVRASGKEYPGVSLNVPGRHNVMNALAAFASGLELGIAPERIIAGLTRYSGMRRRFQIKYDNSAGVLVVDDYAHHPSEVKAAVKAARDGWPNAEIVAVFQPHLFSRTREFADEYGWALLRADKIYVADIYPSREKAADYPGVSGSLVAAAVHKAGGKHAEFIADRELLYQTVETCPQKSTVVLFMGAGDITHLSTRLAGEWINKFSA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP1_ROTSF
Sequence: MATFKDACFHYRRLTALNRRLCNIGANSICMPVPDEKIKGWCLECCQIADLTHCYGCSLPHVCKWCVQNRRCFLDNEPHLLKLRTVKHPITKDKLQCIIDLYNIIFPINDKVIRKFERMIKQRKCRNQYKIEWYNHLLLPITLNAAAFKFDENNLYYVFGLYEKSVSDIYAPYRIVNFINEFDKLLLDDINFTRMSNLPIELRNHYAKKYFQLSRLPSSKLKQIYFSDFTKETVIFNTYTKTPGRSIYRNVTEFNWRDELELYSDLKNDKNKLIAAMMTSKYTRFYAHDNNFGRLKMTIFELGHHCQPNYVASNHPGNASDIQYCKWCNIKYFLSKIDWRIRDMYNLLMEFIKDCYKSNVNVGHCSSVENIYPLIKRLIWSLFTNHMDQTIEEVFNHMSPVSVEGTNVIMLILGLNISLYNEIKRTLNVDSIPMVLNLNEFSSIVKSISSKWYNVDELDKLPMSIKSTEELIEMKNSGTLTEEFELLISNSEDDNE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: SPT17_HUMAN
Sequence: MATLARLQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNSPFRKEPDPWELQLQKAKPLTHRRPKVKQKDSTSLTDWLACTSARSFPRSEILPPINRKQCQGPFRDITEVLEQRYRPLEPTLRVAEPIDELKLAREELRREEWLQNVNDNMFLPFSSYHKNEKYIPSMHLSSKYGPISYKEQFRSENPKKWICDKDFQTVLPSFELFSKYGKLYSKAGQIV
What are the official names of this protein?
Spermatogenesis-associated protein 17.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_VIBCM
Sequence: MSETQNHNSYGKPVEMTVIGAGSYGTSLAISLARNGANIVLWGHDAEHMARLDADRANHEFLPGIAFPDTLIVETDLQKAVQASRDLLVVVPSHVFGIVLKSLQPHLRADSRICWATKGLEPETGRLLQDVAHDVLGDSYPLAVLSGPTFAKELAMGMPTAISVASPDAQFVRDLQEKIHCSKTFRVYANSDFIGMQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGAQPETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGKDVDTAQTDIGQVVEGYRNTKEVWMLAKRMGVEMPIVEQIYQVLYQGKDARLAAQDLLARDKKMER
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFPL_ECOHS
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: SFXN_DICDI
Sequence: MTSNSFPVFDGVSNKYDNNTFYGRYQNFRDITDPSTLFATEKDLSQSKTLLDNFKKGLVDPVKHSDELWKAKKILDSTIHPDTGKPIFLPFRVSAFLPINVIICAGLILPNASIGTTIFWQWINQSYNIALNHANRNASNTMSNKQILEAYASAVGISCSLAVGLGWGVNKLNIQNKTISSALRMMVPFTAVTSAGIANVLIMRGNEMVNGIDIKDKDGVIHGKSKEAGKSAVYKVAFSRAATSFPALLLPPIVMGLFERTSFVKKYPKVRMPLNLAVIAAIFNTSLPAAIALFPQESTISADSLEPQFRNIKDKNGNIIKEFIYNKGL
What is the function of this protein?
Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria.
What are the official names of this protein?
Sideroflexin.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RL4_BURCH
Sequence: MELKLLNENGQEGAVVNASDVVFGRDYNEALIHQVVVAYQANARQGNRAQKDREQVKHTTKKPWRQKGTGRARAGMSSSPLWRGGGRIFPNSPEENFSHKVNKKMHRAGLCSIFSQLAREGRLSVVEDIILEAPKTKLLADKFKTMGLDSVLIITDTVDENLYLASRNLPHVAIVEPRYADPLSLIYFKKVLVTKAAVAQIEELLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CLPS_YERP3
Sequence: MGKNNDWLNFEHLVKDKQIEALQPPSMYKVILNNDDYTPMEFVIDVLQKFFSYDIERATQLMLNVHYQGKAICGVFTAEVAETKVAHVNQYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: YOCC_BACSU
Sequence: MFTVKEKNRQELEEELNDLEFQIYRMQENMKDLSKDAKVLGIDQSKHDEWMIVSSIDDGQTCKIMLTDCKTAYRGKGCFSLVASYKDDAIHIGDIKGPPNHGFGSICMKYLKDIARDHNIPKVTGDIAKRDWNHVDRLIHFYEKHHFKVCIDHDTQSGSIKWVDL
What are the official names of this protein?
Uncharacterized protein YocC.
Protein: CCD32_DANRE
Sequence: MMIDDFETHAARSSGDLWSEVCSSLPEPREQHGGQFTDSFEPSSPGDPHTDSPRAANFSPWEPMADSEVYIAGLENRLKRIKGQTSEVTSREMLRSLSQAKKECWDRFLHDAQTSELFQEGNFDQSALEQFKRWLSPERVAINAEELEYLLLPTQNSETPASSSQTDKPCVEEEEECPSPEK
What is the function of this protein?
Has a role in ciliogenesis and is required for proper cephalic and left/right axis development.
What are the official names of this protein?
Coiled-coil domain-containing protein 32.
Protein: ARGC_PHOLL
Sequence: MLNTLVVGASGYTGAELAAYLHRHPHMNLIRLMVSAQSVDADKCFSDLHPQYKGIVDLPLQPLTDIINAAKGIDVVFLATAHEVSHDIAPLFLAAGCTVFDLSGAYRVQNAQIYQQYYGFKHKHTEWLAQAVYGLAEWQAENIKQAQLVAVPGCYPTVSQLCLKPLLENSLLDISYWPVINATSGVSGAGRKASMTNSFCEISLQPYGIFTHRHQPEIEEHLGTRVVFTPHLGNFARGILATITCKLKPGVTAEQIDEVYRQAYKDKPLVRLYSKGVPALKSVVGLPFCDIGFVVQGDHLIVVGTEDNLLKGAAAQAVQCMNIRFGFEETQALL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLDH_MACFA
Sequence: MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQLIDADVTVIGSGPGGYVAAIKAAQLGFKTVCVEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVIHVNGYGKITGKNQVTATKVDGGTQVVDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGIGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF
What is the function of this protein?
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex).  The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion.  A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.  In monomeric form may have additional moonlighting function as serine protease (By similarity).  Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (By similarity).
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, mitochondrial, Dihydrolipoamide dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mainly localizes in the mitochondrion. A small fraction localizes to the nucleus, where the 2- oxoglutarate dehydrogenase complex is required for histone succinylation.
Protein: S61G2_ARATH
Sequence: MDAIDSVVDPLRDFAKDSIRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVGFFVKLIFIPINNIIVGAT
What is the function of this protein?
Necessary for protein translocation in the endoplasmic reticulum.
What are the official names of this protein?
Protein transport protein Sec61 subunit gamma-2.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SYA_STRSV
Sequence: MKQMSSAQVRQMWLDFWATKGHAVEPSVSLVPVNDPTLLWINSGVATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRDEAIEWAYELLTSPEWFDFPKDKLYMTYYPDDKDSYNRWIAMGVEPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEAFDPENIGVRLLEEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMSFKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTVGKIMESYYPEVLEKQEFIEKIIKSEEESFARTLHSGQHFAETIVADLKAKGQTVISGQDAFKLYDTYGFPLELTEEIAEEADMTVDRAGFEAAMKEQQDRARASVVKGGSMGMQNETLQAITVESAFNYEKEELTAELLAIVADDAAVESVETGTAALIFAETPFYAEMGGQVADHGQIFDGAGNLVAQVTDVQKAPNGQPLHTVEVLAPLALGQSYKLEIDHSRRHRVMKNHTATHLLHAALHNVLGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQEVNEKIWEALAIETVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSVELCGGTHVGNTSEIGIFKIVKEEGIGSGTRRILAVTSKEAFEAYREEEEALKAIAATLKAPQIKEVPHKVEALQEQLRQLQKENAELKEKAAAAASGEVFKDVQEANGHSFIASQVSVSDAGALRTFADTWKQKDYSDVLVLVAAIGDKVNVLAASKTKDVHAGNLIKELAPIVDGRGGGKPDMAMAGGSKQSAIPDLLAAVAEKL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC58_XENLA
Sequence: MEGPEVTDGDNVLNLTHLGLENLNLELVSENKRKDVQQILLPHNRLVVLPPLVASFIHLHLLDISNNNMVYIGEEILGLTKLKTLLAKNNRLDEFSFPKEMGGMRLEVLNLSGNRFEEIPDQFLQIPTLKSLSLGGNRLKSIPAEIENLISLEFLYLGGNFISSIPSELANLPYLSYLVLCDNRIQSIPPQLAQVHSLRSLSLHNNLLTYLPREILSLVHLHELSLRGNPLVVRFVRDLTYTPPTLLELAGRTIKSHGIPYCPWELPENLLRYLDLASKCPNPKCSGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCGSTSHSESDSEDEVNVAARRMQKVLLG
What are the official names of this protein?
Leucine-rich repeat-containing protein 58.
Protein: AZOR2_LACPL
Sequence: MTKLLMINAHPHTTVPSASLTVAASFKTAYQQTHPHDEITTRDLYQDGVPALNDTTFEAWRKRKYGEELTSVEAELLSRHASWLAEFLAADKIVFVNPMYNHFLPAELKQYLDLTAVARKTFKYTVNGPVGLLPDKHVLHIQAAGGYYHQPDQHNQVEAGDPYLRGMMQLYGIQDYRTIFIEGLDQFPEQREQAITAAQVAAEKLAGEF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 2, Azo-dye reductase 2, FMN-dependent NADH-azo compound oxidoreductase 2, FMN-dependent NADH-azoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: ERMG_LIMRT
Sequence: MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHFSFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIFGNIPYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPREYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKYARIDDLNNISFEQFLSLFNSYKLFNR
What is the function of this protein?
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics (By similarity).  Is involved in erythromycin resistance.
What are the official names of this protein?
rRNA adenine N-6-methyltransferase, Erythromycin resistance protein, Macrolide-lincosamide-streptogramin B resistance protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: RL3_STRP4
Sequence: MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETDGYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAGRMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YE38A_YEAST
Sequence: MIIIFIELCRIADSLLWIPKSSRRTSSISTYLIL
What are the official names of this protein?
Putative uncharacterized protein YER138W-A.
Protein: MAP1_HELPJ
Sequence: MAISIKSPKEIKALRKAGELTAQALALLEREVRPGVSLLELDKMAEDFIKSSHARPAFKGLYGFPNSVCMSLNEVVIHGIPTDYVLQEGDIIGLDLGVEVDGYYGDSALTLPIGAISPQDEKLLACSKESLMHAISSIRVGMHFKELSQILEGAITERGFVPLKGFCGHGIGKKPHEEPEIPNYLEKGVKANSGPKIKEGMVFCLEPMVCQKQGEPKILADKWSVVSVDGLNTSHHEHTIAIVGNKAVILTER
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: VPB47_MYCTO
Sequence: MRATVGLVEAIGIRELRQHASRYLARVEAGEELGVTNKGRLVARLIPVQAAERSREALIESGVLIPARRPQNLLDVTAEPARGRKRTLSDVLNEMRDEQ
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Antitoxin VapB47.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: RMAR_YEAST
Sequence: MKLKLLNMILSMMNKTNNNNNIIINNTLDSLMNKKLLLKNMLLDMNNKKMNNMKRMLNNNNMNPAGANPVVHRIGPAGNINNKLQHLNNMNNWNTQIYNYNKNMEIMNTMNDKLINKLLYKMMTLKLNNMNINKIIMSKTINQHSLNKLNIKFYYYNNDINNNNNNNNNNYYMNMMNKLMNIMNNNMNNNLCNILSYYYKKKVTIEPIKLSYIYLNSDIFSKYISLNDMDKYNNGILTNYQRMLNNIMPKLNDHNISMNYINNINNINNNKYNNMINLLNNNNNINNNNNYNNNNNNYIGNINNIYNNMTIDNIPMDILMYKYLVGWSIKFKGRLSNNNGRTSTTNLLNGTFNNKKYLWSNINNNYKLNYIPSNHNLYNNSNINKNGKYNIKVKLNFI
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:25609543, PubMed:28154081).  uS3m is essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits (PubMed:7770043).
What are the official names of this protein?
Ribosomal protein VAR1, mitochondrial, Mitochondrial small ribosomal subunit protein uS3m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: BLTP2_HUMAN
Sequence: MPLFFSALLVLLLVALSALFLGRWLVVRLATKWCQRKLQAELKIGSFRFFWIQNVSLKFQQHQQTVEIDNLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVSDLSAPFSQSAGVDQKELSFSPSLLKIFCQLFSIHVDAINIMVLKVDTSESLWHIQISRSRFLLDSDGKRLICEVSLCKINSKVLKSGQLEDTCLVELSLALDLCLKVGISSRHLTAITVDVWTLHAELHEGLFQSQLLCQGPSLASKPVPCSEVTENLVEPTLPGLFLLQQLPDQVKVKMENTSVVLSMNSQKRHLTWTLKLLQFLYHRDEDQLPLRSFTANSDMAQMSTELLLEDGLLLSQSRQRIVCLNSLKASVQVTTIDLSASLVLNTCIIHYRHQEFSHWLHLLALETQGSSSPVLKQRKKRTFPQILAPIIFSTSISNVNISIQLGDTPPFALGFNSISLDYQHLRPQSIHQRGVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSDTLFLDCTIRGLQVEASDTCAQCLSRILSLMGPQSGKSAVSRHSSFGESVSLLWKVDLKVEDMNLFTLSALVGASEVRLDTLTILGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRSLEVQCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATVFPETVPSLALETSGTTSELEGRAPEPLPPKRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGNSIFNFKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSFGSVSVEFPYQYDFSRTLDEAVGVQKWLKGLHQGTRAWASPSPVPLPPDLLLKVEHFSWVFLDDVFEVKLHDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPEHVVEQVQELDPGSPFPPEGLDLVIQWCRMLKCNVKSFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILHLGLPWGNVAVERNMPPLKFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGDLDINVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHSVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIKMDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVTQMVSDLSQVTVHLMASPTEENADHCLDPLVTKTHLLSLSSLTYQRHSNRTAEEELSARDGDPTFHTHQLHLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMPAKKPKRGVPTSASAPPRVNTPSFSGQPDKGSSGGAYMLQKLIEETDRFVVFTEEESGMSDQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRQRSLDSVQELMESGQAVGGMVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVLENQEKEDLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSIMKSLQDDSKNENLLDLNQKLQLQLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRSVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGPGKGVAQGLTRSSGVRRSFRKSPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKSATGSEVRGKLETKSDLNMQQQEEEEKARLLIGLSVGDKNPGKKSIFGRRK
What is the function of this protein?
Tube-forming lipid transport protein which binds to phosphatidylinositols and affects phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) distribution.
What are the official names of this protein?
Bridge-like lipid transfer protein family member 2, Antigen MLAA-22, Breast cancer-overexpressed gene 1 protein, Protein hobbit homolog.
What is the protein family that this protein belongs to?
Belongs to the SABRE family.