PharMolix/UniProtQA huggingface dataset:
Protein: GLNA_RAT
Sequence: MATSASSHLNKGIKQMYMNLPQGEKIQLMYIWVDGTGEGLRCKTRTLDCDPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRRDPNKLVFCEVFKYNRKPAETNLRHSCKRIMDMVSSQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLRCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRIVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCLLNETGDEPFQYKN
What is the function of this protein?
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (PubMed:28323).  Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity).  Essential for proliferation of fetal skin fibroblasts.  Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation.  May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (By similarity).  Plays a role in ribosomal 40S subunit biogenesis (By similarity).
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Palmitoyltransferase GLUL.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Microsome. Mitochondrion. Cell membrane; Lipid-anchor. Note=Mainly localizes in the cytosol, with a fraction associated with the cell membrane.
Protein: PA2A6_CROHD
Sequence: MRTLWIVAVLLLGVEGSLVQFEMMIMEVAKRSGLLWYSAYGCYCGWGGHGRPQDATDRCCFVHDCCYGKATDCNPKRVSYTYSEENGEIVCGGDDPCGTQICECDKAAAICFRDNIPSYDNKYWLFPPKNCQEEPEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows high lipolytic and weak ADP-induced platelet aggregation activities.  Also shows weak anticoagulant activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Acidic phospholipase A2 CH-E6', svPLA2, CH-E6, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AP1M2_ARATH
Sequence: MAGAASALFLLDIKGRVLVWRDYRGDVSAAQAERFFTKLIEKEGDSQSNDPVAYDNGVTYMFVQHSNVYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQYTEARILSEFIKTDAYRMEVTQRPPMAVTNAVSWRSEGIQYKKNEVFLDVIENVNILVNSNGQIVRSDVVGALKMRTYLTGMPECKLGLNDRVLLEAQGRATKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGAFDLMTYRLSTQVKPLIWVEAQIESHSRSRVEMLIKARSQFKERSTATNVEIELPVPTDASNPTVRTSLGSASYAPEKDALVWKIKSFPGNKEYMLRAEFHLPSITAEEATPERKAPIRVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITMAGEYELRLV
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting at the trans-Golgi network and early endosomes (TGN/EE).  The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.  Required for KNOLLE localization at the cell plate to mediate cytokinesis.  Functions redundantly with AP1M1 in multiple post-Golgi trafficking pathways leading from the TGN to the vacuole, the plasma membrane, and the cell-division plane.
What are the official names of this protein?
AP-1 complex subunit mu-2, Adaptor protein complex AP-1 subunit mu-2, Adaptor protein-1 mu-adaptin 2, Adaptor-related protein complex 1 subunit mu-2, At-muB2-Ad, Clathrin assembly protein complex 1 mu-2 medium chain, Mu1-adaptin 2, Protein HAPLESS 13.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CLU_ASPOR
Sequence: MAQTNGELEHSKAETPEQLTNGNHPEETQEEEQNGGLFQISVKLPHEPYKIQVMVSSQEQVQDVRQSIVELPSTFQYTCFHLEFNGKRINDFVELSEVPDLKADSEIVLVEDPYTEKESRMHVIRMRELVGAAGDRVDNLQGISAGLSLHDSISEEAAAGETTEKEHSLSKYDIAGSPSLNTILPKAEAPLPKTVKSISLSPWNPVPYHLRQKGHLLYLQVTTNEGEQFQITSHVSGFFVNKCSNARFDPFPKPMPKKGSAHSLLTLISHLSPSFTTSFEALQEANNKKDLLTTFPFQNAIPNSPWLVAPPSSSVNAHQPDITRSQENYLISGVDNAETLRDWNEEFQTTRELPRDTVQDRVFRERLTSKLFADYNEAAARGAVLVAKGEVAPLNPTEDRDAQIFVYNNIFYSFGADGVGTFASEGGDEAARVAVGKDVVGIKAVNQLDINGLFTPGTVVVDYLGKRIVGQSIVPGIFKQREPGEHQIDYGGVEGKDVVATHPDFVPVFEKLSKALRIKKHAVWDKDGKRHDLEGSVETKGLLGTDGRKYVLDLYRVTPLDVMWQEEEGSDAYPHNMSVLRLELVESYWRHKMSQYVKAEVERRRAAKAVETASKEKSEENAESKEEGSEEKSEEALDQERVDISGFSLALNPDVCSGQIPQTDEEKEQWAQDEKEVRETCDFLRSKVMPELIQDLHDGDVGFPMDGQSLSQLLHKRGINIRYLGKLAQMSKEKGARLDALTLLLVQEMIARAFKHIANSYLRNVAAPFTASCIAHLLNCLLGADVNSNPQADIDASLREIYPEADFSFEKVTPTTLRAEIEKHVSTRYRYTPEPEWFNSLRHLQLLRDISIKLGLQLSAREYAFAKSQLPAKVPATNGASQEEGKKKKKKGGDSKSPARAASPEKPAVSIVPDDIVNIVPLVKDASPRSSLAEEALEAGRISLMQNQKQLGQELILESLSLHEQIYGILHPEVAKLYHQLSMLYYQTDEKEAAVELARKAVIVTERTLGVDSADTILSYLNLSLFEHASGNTKTALVYIKHAMDLWKIIYGPNHPDSITTMNNAAVMLQHLKQYSDSRKWFEASLTVCESLFGRQSINTATILFQLAQALALDQDSKGAVGKMRDAYNIFLSQLGPEDRNTKEAETWLEQLTQNAVSIAKHAKDIQARRLRRINMNTRTLGTKVQPQVGQSAPSASGASSANPSLDSRSIDELLKFIEGGDTSSSRTKQKKRAAASNPKLRGSKKSSA
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog, Protein TIF31 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_RICRO
Sequence: MLYNLLLPHIHNSHIANLFHYITFRSGLAIIITLSLSFITGPILIEFLRSIQKNGQPIRSDGPESHQTKVGTPTMGGIMIILSSCLSTLLLADLTNKYIWITLFGFISFGIIGFMDDYAKVTKNNHYGVRGKSKLLLQGIISVIICVLLEYLDKSPSHLLNVPFFKNLSLDLGYCYIVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTAGSFALISYLVGNLIYSNYLQLTYIPNTGELTVLCAGLVGSCLGFLWFNAQPAEVFMGDTGSLSLGGVLGIISVITKHEIVLAIVGGLFVIETASVILQVYYFKATKGKRIFKMAPLHHHFEKHGWAESKVVIRFWIISVIFALIGLSSLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNH2_LACGA
Sequence: MTITEIRNLLQGEVSSEQLEELRADERKGVQKLLISYEKRQAKRAQAVAQFQDRFSYEKKFWQKSQLVAGVDEVGRGPLAGPVVTAAVILPHNFDLIDVNDSKKLSPKKRKELFPKILAKAVSVSVGLANNDVIDRINIYEADRLAMAHAVQGLKVKPDALLVDAMNVPLNIPQVKLIHGDAKSNSIAAASIVAKVFRDNLMDAYGEVYPEYDFKHNAGYGTREHMEALKKYGPTPIHRRSFAPVSEYEK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 246L_IIV6
Sequence: MLIKFLIIPINGKKTLIQYSKSGFDEETRKYIPTLRRTDLLRIAKNCNIQLSKEMYDFEISNKIIHWKPSSLSYSRKELTKLTKKDIISLFNIHNINTTKAECKFDLIESFLQQQKLYFYENLDEE
What are the official names of this protein?
Uncharacterized protein 246L.
Protein: RUVA_SHESR
Sequence: MIGRLRGVLIEKQAPEVLIDVNGVGYELQMPLTSFYELPEVNQPTTVYTHFVVREDAQLLYGFITKQERSLFRLLIKANGVGPKLALTILSGMTASEFVGCVERDDIVTLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFVLQSNYSPAPTVNSAEEDAISALISLGYKPPQASKAVSAAYKEGMDSETLIKAALKSML
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: WZYE_ECOLC
Sequence: MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ROGF3_ARATH
Sequence: MENLSNPDENDDHQSPRSIDQNDQSAVETPVYSTMSIDSFVYPRTCSETTSGFSDQIDETNSFCSEASPCNWPVLTESKSSKCLSGLEMQSNECLVVQEISEPELETMKERFAKLLLGEDMSGSGKGVCTAVTISNAITNLYATVFGQNLRLEPLETEKRALWKREMNCLLSVCDYIVEFIPRCQNLSNGATVEVMESRPRADIYINLPALRKLDSMLMEALDSFQNTEFWYAEEGSLSMKSARSSTGSFRKVIVQRKEEKWWLPVPLVPSEGLSDKARKQLKNKRESTNQIHKAAMAINSSILSEMEIPDSYMTTLPKCGKSSVGDSIYRYMSGSGRFFPEQLLDCLNISSEHEAVQLADRVEASMYTWRRKSCLSNSKNSWNMVKDLMSTTERTDKNYVMAERAETLLFCLKQRYPELSQTSLDICKIQYNKDVGKAVLESYSRVLEGLAFNIVAWIDDVLYVDKTMRGSE
What is the function of this protein?
Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP.
What are the official names of this protein?
Rop guanine nucleotide exchange factor 3, AtRopGEF3, Rho of plants guanine nucleotide exchange factor 3.
Protein: PSB3_YEAST
Sequence: MSDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD
What is the function of this protein?
Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity.  This subunit may participate in the trypsin-like activity of the enzyme complex.
What are the official names of this protein?
Proteasome subunit beta type-3, Macropain subunit PUP3, Multicatalytic endopeptidase complex subunit PUP3, Proteasome component PUP3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DRS2_PHYSA
Sequence: ALWFTMLKKLGTMALHAGKAALGAAANTISQGTQ
What is the function of this protein?
Potent antimicrobial peptide with activity against bacteria and protozoa (By similarity).  Also has activity against fungi (PubMed:8306981).  Probably acts by disturbing membrane functions with its amphipathic structure (Probable).
What are the official names of this protein?
Dermaseptin-S2, DRS-S2, Dermaseptin II, DS II, Dermaseptin-2, DS2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPD_SCHPO
Sequence: MNMEQEDDQVPAVAAETVPLKRYVTNPGANRDEEVAAAPSSQDTPYFDYAYERSLRHQDAKFLAMNGTQNGRDGLPSKSPRRPSVSASTVRNSDDVNHSKAGPGSGKLLNDTLQSKISSIHMPHVQQGDNAVVSSVGGPETDPGNMETTDPLFSDELAEIYLSIHKCMDMRHKYIRVSLQGELDNPIDDDSWIIYPDCKEGEDDTGLFNFADCKIPGIENEMEYHMDHQGIFQVYENDSAYIAGTPSFHIPTIRDYYIDLEFLLSASSDGPSKSFSFRRLQYLEGRWNMYMLLNEYQELADTKKVPHRDFYNVRKVDTHVHHSALANQKHLLRFIKAKLRKCPNEKVIWRDGKFLTLQEVFDSLKLTSYDLSIDTLDMHAHTDTFHRFDKFNLKYNPIGESRLRTIFLKTDNDINGRYLAELTKEVFTDLRTQKYQMAEYRISIYGRNREEWDKLAAWIIDNELFSPNVRWLIQVPRLYDVYKKSGIVETFEEVVRNVFEPLFEVTKDPRTHPKLHVFLQRVIGFDSVDDESKPERRTFRKFPYPKHWDINLNPPYSYWLYYMYANMTSLNSWRKIRGFNTFVLRPHCGEAGDTDHLASAFLLSHGINHGILLRKVPFLQYLWYLDQIPIAMSPLSNNALFLAYDKNPFLTYFKRGLNVSLSTDDPLQFAFTREPLIEEYAVAAQIYKLSAVDMCELARNSVLQSGFERQLKERWLGVDFQDIDRTNVPIIRLAYRALTLTQEIALVNKHVQPSKHPSNHDLEELIHKYDAMTGTSDPLSASPRTNDATISSRLSLHDGHDHGAFFPGLSVISERRRRKDSMASSSQDLKD
What is the function of this protein?
AMP deaminase plays a critical role in energy metabolism.
What are the official names of this protein?
AMP deaminase, Myoadenylate deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_PELPD
Sequence: MRKYETIYILQPDLSEDDIKVVADKVQDVITSYKGDFQRLEDWGIRKLAYPINKCARGRYLYLRYDGGREMIAELERRLRLDEKVLRFQSVNITNQPEKPVVEKKPVPVEAEAVESAEAVAAPAETVSE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: LSRD_ENT38
Sequence: MKLNWETTLLILLVLEILLFGAINPRMLDINMLLFSTSDFICIGIVALPLTLVIISGGIDISLGSTIGLCAIALGVMMQFGLPMYLAVPLTLLLGLLCGLFNAALIHYTGISPLVITLGTLYLYGGGALLLSGLAGATGYEGIGGFPDSFTAFANLTVLGLPIPLVLFAVITFFFWLITHRGRFGRHLFLIGQNPRAARYAALSVNGMPYALYGLVGVASAIAALVMVSYFGSARSDLGRDLLMPALTAAVLGGANIYGGSGSVIGTALAALLVGYLQQGLQMVGIPNQVSSALSGALLVVVVMGRSLSLHREWVRNFFTKHTRSLR
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_LEPBJ
Sequence: MLSPKRVKFRKRQRGRLKGTDERGSSVSFGEFGLKAVTSGRLTARQIEAARITINRQVKRGGKLWIRIFPHTPITKKPAETRMGKGKGNPEFWIAEIRPGRILFEMSGIDEETAEKALSLASYKLPIHTEFVKRSAL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SOCB_MYCTU
Sequence: MWTLKARKEHTGISGKPTARTDRHGSTRSGDSELQASARRFSRLPDRCGAQGVT
What are the official names of this protein?
Uncharacterized protein SocB, Small ORF induced by copper B.
Protein: RS6_RICBR
Sequence: MSFYESVFIVRQDVSLNDIDKIVDDFSKIIKDNNGAIVKKEYWGLRALAYKIGNHKKGHYYLLGLDTTPAVKQELERKMKLNENIIRFLTQKVDSISNEPSPILKNQSTENTPVIDVTAN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: FCHA_METEA
Sequence: MAGNETIETFLDGLASSAPTPGGGGAAAISGAMGAALVSMVCNLTIGKKKYVEVEADLKQVLEKSEGLRRTLTGMIADDVEAFDAVMGAYGLPKNTDEEKAARAAKIQEALKTATDVPLACCRVCREVIDLAEIVAEKGNLNVISDAGVAVLSAYAGLRSAALNVYVNAKGLDDRAFAEERLKELEGLLAEAGALNERIYETVKSKVN
What is the function of this protein?
Required for both C1 and C2 metabolism.
What are the official names of this protein?
Methenyltetrahydrofolate cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the cyclodeaminase/cyclohydrolase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ITB6_MOUSE
Sequence: MGIELVCLFLLLLGRNDHVQGGCAWGGAESCSDCLLTGPHCAWCSQENFTHLSGAGERCDTPANLLAKGCQLPFIENPVSRIEVLQNKPLSVGRQKNSSDIVQIAPQSLVLKLRPGREQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDHRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCNNGVLFPHQKKCSHMKVGDTASFNVTVSVSNCEKRSRNLIIKPVGLGDTLEILVSAECDCDCQREIETNSSKCHNGNGSFQCGVCTCNPGHMGPHCECGEDMVSTDSCKESPGHPSCSGRGDCYCGQCICHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNCTTNRDSCTSEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSKRSCIECYLSADGQAQEECADKCKAIGATISEEDFSKDTSVSCSLQGENECLITFLITTDNEGKTIIHNINEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKAGLSSDG
What is the function of this protein?
Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity).  It recognizes the sequence R-G-D in its ligands (PubMed:10025398).  ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity).  Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:10025398).
What are the official names of this protein?
Integrin beta-6.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.
Protein: DTDA_CALMQ
Sequence: MKIGLIVSRVDEASIGIWSMLKGMVKFKEINTNEYSSDLALALVSDKDIVYVDEADEWARVNDIDLLLFLSRHEMKNPKPLITFHTPGNWTNDVELGGKPGQVAISEPRVLTNLFREAYRRIGELNGYSVTLEATHHGPFVDKPVVFVEIGSTSNEWRDPKAQEFLASLVFDLLNNTDKYINDGKDAAVSIGDLHYTTLVNHIINGEYDVGHMVPKYIKPTPTIIKMAVERNTVRPRIGIIHWKSLDAESRVMSEKELSNLGLTVIKRR
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: Y584_RICBR
Sequence: MISDISFLQDFAEFIVSKFGKENLRKELKIILPNSLSCTKLKGLLTDNYNVQNLPIIIPFNAIISKKDSSEDYMSKMEELFTLSKIITEYKKLDFTPEEALKAAGILNKLFADLVNNNVDIKLIETYNNSEYWQNIYKFLEYSFLKWQKNEKQSSNNYKLKLLLEEIARTKNSCKQVILAGIFKPDSFLKKYEEELQIIKYNEIKLAHNNIYYYEPTDIYEEAEQIAHICKQNADKKIAIVINNNKLKRIYCNYLDKYELVFEDLIGNDLKLTNVSSLLIAIINILCNNFDLKLLFLLLKNPLINCTNIQELELLLSGKNRFISSPKYLLQLQFDNEELKIYCYNLVDILFTTKPYNIKDILVLSKEIFEKILPDIWEKEGGAELSEFLNNLTEFSGSINVSKKDFPKIFALLLSNVKYYKNIESKIIIGSPEELALSRFDLVILPHFNSDNWSNTTTTHPYLSKEAKQILNIDYDEITPKLYSNYFDLLLQNEEVIILNAKKYAGKLSTPCNLFLKLSNKNVIPNKSVIPQLDCGISGVIFLDSTTSTQDDIEQAAHSTFFPNILSVTDIETLIRNPYGFYAKKILKLRTQDKIWEEPKISDFGNFIHKVLEEYSKNYDQQNMLDQQQALLNIGNNILHSTILPTYTKKTWQTKLTLLSKAFILFDMERRKNCQKIYFEIKGELNLNIAGQNIKIIGIADRIEISKSNCITILDYKTGTIPTKKEIELGLSPQLIIESLMILENGFNISHSYAPLCHSCESGNPIENITIAYVKITSTEPYVQTTEISLSMETLEKHKQGLIRLLEYYVKNKSFVYDLDMSKYNDYLHLRG
What are the official names of this protein?
Uncharacterized protein RBE_0584.
Protein: MSRA_PASMU
Sequence: MTQQAIFAGGCFWCVEAVFNQIKGVEKATSGYINGTTENPTYKEVCTGETGHAEAVKVEFDATVISYEKLLDIFFSIHNPTQLNHQGEDVGTQYRTGIYYLNDEQEQLANKKIAELQPHFAEKIVTEVLPAQTFYPAEDYHQGYLLQNPQNSYCNLVATPKFLKAKVKFEEIWK
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: MALF_ECOLI
Sequence: MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Maltose/maltodextrin transport system permease protein MalF.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Periplasmic side. Note=A substantial portion of it protrudes into the periplasmic space; inserts in an SRP- and Sec-dependent, YidC-independent fashion into the membrane.
Protein: FABA_SHIFL
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (By similarity).
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_GEOMG
Sequence: MARKKISLIGGGQIGGVLAQLCALRELGDVVMFDIVEGLPQGKMLDIAEVGPVDGFDVCLKGTNSYADIAGSDVVIVTAGLPRKPGMSRDDLIEVNSKIMTQVAEGIKQYAPNSFVIVISNPLDAMVTLCQKITGFPYNRVIGQAGVLDSSRFAAFIAWELGVSVKDVVAVTLGGHGDDMVPLVRYTSVCGIPVMELLERKYKDKAKAKEVMEAMVKRTRGAGGEVVALLKTGSAFYSPASAAIAMTESILKDQKRVLPTCCFLQGEFGVNGYYVGVPAVLGENGVEQIIQFNLDAEEQAMMDKSVAAVKSLVDSLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.