PharMolix/UniProtQA huggingface dataset:
Protein: ICK7_TRILK
Sequence: MKTIIVFLSLLVLATKFGDAKEGVNQEQKKEVTQNEFRVEYLNEMAAMSLLQQLEAXESALFEKEAGRNSRQXRCAMGDVPCTKGKTNCCKGYECKPKSPSWWYDTDFCQPIHGGRPIGI
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U13-barytoxin-Tl1a, U13-BATX-Tl1a, Toxin ICK-7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 05 (ICK-7) subfamily. ICK-7 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: 3MGH_ANASK
Sequence: MKLPQAFYARDTRTVARALLGKVLVHLDGGVRRAARIVETEAYHGPDDRASHARAGPTPRAAIMFGPPGRAYVYLIYGTSHCMNVVTGPEGFPSAVLIRAAEPIEGCLHSTRGPGNLCRALAIRREHDNGRDLGGDDLFVEDAPPPAEAVVTGPRVNVGYAGAWAARPWRFALRGSPWVSRPAPGAAAARAARAPAAPAPRPRRPRGSGP
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RL30_SHEDO
Sequence: MATKTLKVTQTKSGIGRLPKHRATLTGLGLRRIGHTVELEDTPSVRGMINKVYYMVSVEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: U312_DELAC
Sequence: APATYAIDPTHTFATFEIDHNGASTNRVRFKSGTVEFDRXAKAETNGGDFEARIDRNAFGV
What are the official names of this protein?
UPF0312 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family.
Protein: COX2_LYCSM
Sequence: MPHASQLSLQEAMGPTMEEVIFLHDHVLLLTCLMTMVITMFTLTATTTALTHNDPTEEVEQLEAAWTVAPIMILILTALPSVRSLYLMEEVFNPYLTIKATGHQWYWNYEYSDGVKISFDSYMIQTKDLQNGSPRLLEVDHRMVMPAGLQTRVVVTAEDVLHSWTIPSLGVKVDAVPGRLNQLPLATSRVGVFYGQCSEICGANHSFMPIAMEATPLHHFEQWLISEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PDXH_RHIME
Sequence: MTANELITGDFTDASEPFSLFGTWLKEAEKNEVNDPNAVALATVDPDGMPNVRMVLLKGFDERGFVLYTNFESQKGREMLATRKAALCFHWKSLRRQVRLRGPVEIVSDEEADEYFMSRPRGSRIGAWASKQSRPLESRFALEKAVAEYTARHAIGEIPRPDYWSGFRIRPLSIEFWHDRPFRLHDRVEFRRETPDGGWTKVRMYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: SECA_RICCK
Sequence: MLSILKKLFGTANDRTVKKLFSEITKINSLEPVIQKLSDEELKNKTVEFKEKLKNGATLDDILYEAFAVVRESARRVCGMRHFDVQLIGGLILHQGMITEMRTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLASRDSASMGKIYNFLGLSVGCIVAGMSDEAKRAAYNADITHATNNELGFDYLRDNMKYSIQERVLRPFNFAIIDEVDSILIDEARTPLVISGPVNDNSELYTKIDKIVRQLKAGDFEKDEKLKTIHLTELGITHIESLLSNENIIKPDSGLYDFENLTLVHYINQALRAHNMFNVDVDYLVRDGQVMIIDEFTGRVMEGRRYSEGLHQALEAKENVKIQNENQTLASITFQNYFRNYPKLSGMTGTAMTEAPELKDIYNLDVVAVPTHNKVTRVDLDDEIYGSKKEKYDAILKLIKDCYNRGQPILVGTISIEKSEELSSVLNKEKIPHKILNAKFHEQEAFIIAQAGRFRAVTIATNMAGRGTDIMLGGNPEMLIEQLAKDHSYEAKIAEIKAQIAEEKKKVIEAGGLFVIGTERHESRRIDNQLRGRSGRQGDPGKTQFFLSLDDDLMRIFASERISGVLRTLGLKDGEAIHHPMISRSLEKAQQKVEGHNYEIRKNLLRFDDVMNDQRKIIYEQRTEIIKSKDSYDFLNSTTAELAKKIVLTFMPAGSYREDWDIENLSVELHRIFSIKFDHNLVSKNDVTEEEITKSVIQMAHDIYKSKEESYSSELMHNAVKYILLTTLDQVWKDHLYSLDHLRQGISLRAYAQQDPLSEYKREAFNLFEQMLDNLKELFIQTVYHFHIDLKHVQKEDVSLEHKKFQKNMQESREDPAFSKYNAGSSLEIDLKPVVSRIDPKDRNPEDPTSWGRVSRNELCPCRSGKKYKYCHGANA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RELB_XENLA
Sequence: MREQGREGSSFLSQQLGPTIEDVMDLINSDRDVISSPSVFVCEDAPSSILSTVTVAHYVPHEQCPSTSWAPQREGPNPELNITEQPKQRGMRFRYQCEGRSTGSILGEKSTEHNKTLPEIEIINCDGLEEIHVIVCLVWRDPPHRVHPHGLVGKDCHNGICEVTLNPQNGVAKHSFSNLGIQCVRKREIDSAVNERLKLNIDPYKAGKWRLHEEVDLNVVRLCFQASCTGPGFKYDIPPVLSDPIYDKKSTNTSELKISRMNKEYGRCEGGEEVYILCDKVQKEDILVIFGEDKWEARADFSQADVHRQIAIVLKTPPYHDLHITEPACVRVFLQRITDGIRSEGMPFVYMPRVKDPNGVHSKRKHRDCSQLGDIGDPDPHGIEMKRRKVRPSYADHLIPPYPDINLPLMDSFNHNEGYHDLPLMNPDEDAFHFLTEDPHFSDLLTHDPYFLDGYSNQFLPDQVNGVTAHLVGSSLALTDEEQPLPDCAFNDSGCRR
What is the function of this protein?
Does not bind DNA by itself; probably associates with a p50-NF-kappa-B homolog to act as an activator.  Could be involved in hematopoiesis and spleen development.  May play a role in the regulation of the circadian clock.
What are the official names of this protein?
Transcription factor RelB homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAG2W_AGEOR
Sequence: MRAIISLLLISAMVFSMIEAVPVEEGLQLFEGERGGCLPRNKFCNPSSGPRCCSGLTCKELNIWASKCL
What is the function of this protein?
Insect active toxin causing rapid but reversible paralysis in crickets.  No activity shown in mammals.  Does not show effect on mammalian voltage-gated calcium channels (By similarity).
What are the official names of this protein?
U2-agatoxin-Ao1w, U2-AGTX-Ao1w, Agel_22.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 01 (U2-agtx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECO_PROMM
Sequence: MSGERRLNGLSLKVGPLGEHDRLLTLLSDQEGVTRLAVPGARRPRSSLAAAVPLSLLELQVAGRRGLARVRQLKVLRSFNSVGKQLETLAAAQALAELSLMLVAGNDPLPGLLNTLLMHLERLEALSQAQPAQPNTTLACSVQACVHLLALGGYGLPVQECCRNGTALEPPLGQWEWRCSLMPEEGFAIGALPGAALQLNPSELALLQRLLRPDLPMRRDGELMGPPEVWLRLLAVVECWTRTHLPHHMRALGMLRKAIISSGDGRT
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PPBT_CHICK
Sequence: MKAFLLTLLAQLCSASLVPEREKDPEYWRQQAQETLRDALRLQHLNQNVAKNLILFLGDGMGVSTVTAARILKGQLQHRKGEESLLEMDKFPYVALAKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAGVTRDRCNTTKGQEVTSILRWAKDEGKAVGIVTTTRVTHATPSAAYAHSANRDWYSDGEMPLDALEGGCKDIARQLVDNIPDIEVILGGGRKYMFPKNTSDVEYPQEERHRGTRLDGKDLVQAWHDTKPAGKVAKYVWHRRELLALNVSRVDFLLGLFEPGDMVYELDRNNETDPSLSEMVAVAIRMLQKNPRGFFLLVEGGRIDHGHHEGKAKQALHEAVELDRAVGLAGRLTSPRDTLSVVTADHSHVFTFGGYTPRGNPIFGLAPMQSDVDRKPFTSILYGNGPGYKIVGGERENVSAVDFAHANYQAQAAVPLRQETHGGEDVAVFARGPMAHLLHGVDEQNYIPHAMAYAACIGPNRAHCSSAARPAATATLLPVLLLLLLLC
What is the function of this protein?
Alkaline phosphatase that metabolizes various phosphate compounds and plays a key role in skeletal mineralization and adaptive thermogenesis (By similarity).  Has broad substrate specificity and can hydrolyze a considerable variety of compounds: however, only a few substrates, such as diphosphate (inorganic pyrophosphate; PPi) and pyridoxal 5'-phosphate (PLP) are natural substrates (By similarity).  Plays an essential role in skeletal and dental mineralization via its ability to hydrolyze extracellular diphosphate, a potent mineralization inhibitor, to phosphate: it thereby promotes hydroxyapatite crystal formation and increases inorganic phosphate concentration (By similarity).  Catalyzes dephosphorylation of PLP to pyridoxal (PL), the transportable form of vitamin B6, in order to provide a sufficient amount of PLP in the brain, an essential cofactor for enzymes catalyzing the synthesis of diverse neurotransmitters (By similarity).  Additionally, also able to mediate ATP degradation in a stepwise manner to adenosine, thereby regulating the availability of ligands for purinergic receptors (By similarity).  Involved in the establishment and growth of feather germs (PubMed:8563025).
What are the official names of this protein?
Alkaline phosphatase, tissue-nonspecific isozyme, AP-TNAP, TNSALP, Phosphoamidase.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Extracellular vesicle membrane; Lipid-anchor, GPI- anchor. Note=Localizes to special class of extracellular vesicles, named matrix vesicles (MVs), which are released by osteogenic cells.
Protein: RSS3_ORYSJ
Sequence: MVGSGAAGGGGGGGGGGDHARSKEAAGMMALHEALRNVCLNSDWTYSVFWTIRPRPRCRGGNGCKVGDDNGSLMLMWEDGFCRPRVAECLEDIDGEDPVRKAFSKMSIQLYNYGEGLMGKVASDKCHKWVFKEPSECEPNIANYWQSSFDALPPEWTDQFASGIQTIAVIQAGHGLLQLGSCKIIPEDLHFVLRMRHMFESLGYQSGFFLSQLFSSSRGTSPSPSSFPLKQQQPPPPQLFNWPGHAPPQLPPGASPLFPPGPAAFHPSSRPMPPFPGGGKDESHLFHLPPAAAAKQPQHMDEHHHHQQQPMAAPQQHGGEAPEGDLKWPNGLSFFTALTGRTEDAKFLFGGGGGGGADDGSKTAAAAQDAGHGGAENVEEYLSLESHSNKARRMESAQSTKFKRSFTLPARMSSSTTSTSPSVSASTAPAPPQQQQGMEYRGPHEGGVYSDLMETFLE
What is the function of this protein?
Involved in the repression of jasmonate (JA)-induced genes.  Forms a ternary complex with TIFY11A/JAZ9 and BHLH094 to negatively regulate JA-responsive genes.  Involved in transcriptional regulation in the root tip.  Plays a regulatory role in root cell elongation.  Regulates root cell elongation during salt stress.
What are the official names of this protein?
Protein RICE SALT SENSITIVE 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: BFRL_ABSSP
Sequence: MKGNREVINQLNQVLYHHLCAINQYFLHSRMND
What is the function of this protein?
May perform analogous functions in iron detoxification and storage to that of animal ferritins (By similarity).  Contains approximately 750 iron atoms per molecule.
What are the official names of this protein?
Bacterioferritin light chain, BFR.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: TCYP_BACHK
Sequence: MNTLLVGINVAVMLILVGVLYYMQRKHVSFNKRVFTALGVGIIFGLILQFIYEPTSKVIIESNTWFGLIGSGYVKLLQMIVMPLILVSIISAFTKLQLTKNLGKISGLIIGILILTTGIAAAVGIAASAGFDVSATGLQQGDAESARLKLVEERFTSIEKTTIPDKLLELLPTNPFLDLTGARPTSTISVVIFAAFIGIAFIGVKRKYPEQAELFKKMLDAVYAIVMRMVTLILRLTPYGVLALMAKTVAGSDINAILKLGNFVLASYVALIVMFVIHLLLIALSGLNPIQYLKKVFPVLTFAFTSRSSAGAMPLNIEAQKEKLGISEGIANFAASFGVSIGQNGCAGIYPAMLAMMVAPTVGIDPLQPQFILTLIAVVAISSFGVAGVGGGATFAALIVLSTMNLPIGIVALVISVEPLIDMGRTALNVSGSMTAGLISSKWLGELDQDTYNQDDTKTGEIAS
What is the function of this protein?
Mediates uptake of L-cystine, the oxidized form of L-cysteine.
What are the official names of this protein?
L-cystine uptake protein TcyP, Transporter of cystine TcyP.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COBQ_MYCGI
Sequence: MTGLLVAGTTSDAGKTAVTTGLCRALARRGVKVAPYKAQNMSNNSMVCTSVDGAGAEIGRAQWVQALAARATPEPAMNPVLLKPGSDRRSHVVLMGRPWGQVSSSDWLEGRRALATAAHEAFDELASRYEVVVAEGAGSPTEINLRAGDYVNLGLARHAGLPTVVVGDIDRGGVFAAFFGTVALLSPQDQALIAGFVVNKFRGDVDLLAPGLRDLERLTGRRVYGTLPWHPDIWLDSEDALELAGRRSAQSGARRVAVIRLPRISNFTDVDALGLEPDLDVVFASHPGSLADADLVVLPGTRATIADLAWLRSRGLDSALRRHVAAGRPVLGICGGFQMLGRVIRDPHGVEGPVAGVDGLGLLDVETTFGPDKVLRLPSGRWFGAPATGYEIHHGRITRGDGVDEFLDGARCGQVFGTMWHGALEGDELRSRFLQEALGVAPSGVSFPAAREARLDLLGDLVERHLDVDALLDLAKTGPVAGLPFLPPGAP
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: MURB_SYNR3
Sequence: MEIPADLNLRKDVPLGDFTTWKVGGAADFFAEPDSSDHLEALVHWGRGQQLPMRFIGAGSNLLISDEGLAGLVICSRRLQGSQLDPTTGIIEAQAGEPLPTLARRAAKAGLSGLEWSVGIPGTVGGAVVMNAGAQGGCIAESLIDATVLDPSSGQTRRMSCNELDYDYRHSALQSEALVVLSARFRLQAGVDPSELSARTSSNLHKRTSTQPYQLPSCGSVFRNPEPQKAGRLIEGLGLKGHRIGGAEVSTLHANFIVNTGNAQAADMDALIRHVQAVVKQAHGLQLHPEVMRLGCFANSQAAAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_STRM5
Sequence: MAKLLVLHGPNLNLLGTREPEVYGHTTLADIDQALAAQASTAGHAVESLQSNAEHVLVDRVQAARNDGTAFILINPAAFTHTSVALRDALAAVAVPFIEIHLSNPHTREPFRQHSYFSDKAVGVVCGFGADSYRYAMDAALARVRVAGA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: COLI_LEPOS
Sequence: MLRSVWVYSLGLAVLLQQSGREQCWEHSQCRDLSSEENILECIQACNSDLTAESPIFPGNGHLQPPSEADRNYAKSHFRSTALGRRTNGSVGSSKQAGENAALSILFAALAPPQAEEEMEESESSQQQRREDKRSYSMEHFRWGKPVGRKRRPVKVYPNGVEEESAEAYPTEMRRDLMSDLDYPLLEEVEEELGGENEVLNLQEKKDGSYKMHHFRWSRPPKDKRYGGFMKSWDERSQKPLLTLFKNVIIKDGHQKKGQ
What is the function of this protein?
Endogenous opiate.
What are the official names of this protein?
Pro-opiomelanocortin, POMC, Corticotropin-lipotropin.
What is the protein family that this protein belongs to?
Belongs to the POMC family.
What are the subcellular locations of this protein?
Secreted. Note=Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
Protein: HEMH_SHIFL
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEDGSPLMVYSRQQQQALAQRLPDTPVALGMSYGSPSLESSVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALGMVPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_CHLAB
Sequence: MTILCELESGVSLPEYATEGASGADLRANIKEPMAVLPGQRVLVPTGIKMQIPQGYEVQVRPRSGFALKHGIMVVNSPGTIDADYRGEVCIILANFGESTFIIEPKMRIAQAVVAPVVQAKFIAVDQEEGLTTTSRGSRGFGHTGEK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RPOA_ANGEV
Sequence: MIQDEVPVSAQTIQWRCIESKIESKRLHYGRFAISPFRKGQANTVGIAIRRSLLGEIEGTAITYAKSKNVIHEYSTIIGIEESINDILINFKEIVLRSDSYETQKAYISITGPKDITAEDILLPPSVQAIDDSQHIATITKDITLDIEIEIQKDRGYRIQDSKESQAGEFFIDAVFMPIRKANYSVHSFGNNKKFQEILFIEIWTDGSLTPKEALYEASRNLIDLFLPFLHTEEEEIISDRDEKSESNGNILLSNSISTDIDRMAKEVAFKHIFIDQLELPARAYNCLKKVDVHTISDLLKYSQDDLRKIKNFGKKSVDQVLEALQERFAINLPRNKFSID
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTRB_METMA
Sequence: MSIVRIAPEINLVMDTESGTVTQERKDSIQYSMEPVFERVDKLDAIADDLVNSLSPSKPLLNTWPGRENTSYIAGIYSNSFYGIIVGLAFSGLLALIIYITRLMGGVV
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit B, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B.
What is the protein family that this protein belongs to?
Belongs to the MtrB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: END4_MYCPU
Sequence: MIKLGSHVSFKSPNYLYDSIKESIKNGANCAMIFLGAPQNTKRVDFEKYQYEKYLKDFSNLIKPEDIVVHAPYIINPASLEKADFAISFLSSEIKRMDKAKFKYLVLHPGFYGKNNVKDSLDQLARSIQKIFEITKDSNVEIMLETMSGKGSEVGKSYEEILYVIDKVKSPRLGACLDTCHVWDAGYNINDYQVFKDELIKTGILKHIKVIHLNDSKNELGSHKDRHANIDKGLIGLKNLKRIVHDPIFENIPIILETPWTEKGPIYDQEIAMLLEK
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: TRPR_ECOSM
Sequence: MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEDVLLKDH
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_SYNWW
Sequence: MIVSAMEKAEILVEALPYIKDFYGRRVVIKYGGAAMTDCELKQKVMQDIVLMKFVGMHPIVVHGGGPEINQMLSRLGIQSEFVNGFRVTDAATMEIVEMVLGGKVNKEIVAGIHASGGKAVGISGKDGMLIQAHPADGSGKMGFVGEVQYVNPELIEKVIENGYIPVIAPIGIGEDQQSYNINADLVAAAIAVSMKADKLVLLTDVPGLMMNPADSNSLISVLKVSEVENYVQEGIIAGGMVPKVQCCVEAVTGGVGRTHIIDGRVPHSILLEIFTDEGIGTMVVNE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDPA_PSEMY
Sequence: MPIRHCIVHLIDKKPDGSPAVLHARDSELATSQAMENLLADLNESYNAKQGKAWGLFHEESGAYPFSGWLKAYLDGEQDFTAFSRQAVEHLQKLMEESNLSTGGHVLFAHYQQGMTDYLAIALLHHSEGVAVTDALDVTPAKHLDLGQLHLAARINISEWQNNKQSKQYISFIKGKNGKKVSDYFRDFIGCQEGVDGPGETRTLLKAFSDYVESEDLPEEQAREKTKTLVGYATGQAKMGEPITLEELSGLIDEERPKAFYEHIRNKDYGMAPEFPADKRTLSQFQRFTGRAEGLSISFEAHLLGSKIEYDEGRDMLIIRQLPTQLKDQLKRRQD
What are the official names of this protein?
Nucleoid-associated protein Pmen_3549.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NADK2_GEOKA
Sequence: MDMERNRLYFFYKRDDKLIERVKPLIELAERGPFVVVDDYREANIIVSIGDDGAFLQAVRQTGFLPDRLYVGVSVLPARGFYCDFHIDDIDHMVEAAKNWKLEVRRYPIIEVTIDGAASFFCLNECSIRSQIIKTMAIDVFIDDLHFETFRGDGIIVSTPTGSTGYNKSVHGAVVDPLLPCFQVSELASLNSNRYRTLGSPFILSGSRTLTLKMSEETSHFPIIGLDNEALSIQHIERIDIRLSDRVVKTVRLKDNSFWDKVKRVFL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_CRPVK
Sequence: MEALSQRLDSIQEELLSLYEKESTSLESQLQHWNLLRKEQVLLHFCKKHGIRQLGYTPVPSLLTSQECAKQAIEMVLYIESLLRSPYSDEPWTLQDTSRERFESPPQKTFKKNPAIVEVYYDGDRGNNNEYTLWGIFIIGNADGEWVKTESGVDYRGIYYVDSEGNYVYYVDFSTDAGRFAANGHYDVVFQNMRLSSSVTSSPQPLVSAPEDTVPEEAPDSAVPAAQKKTGPKTTRTLGRRRSRSPGVQRRPAKQRKQAAPDEADSAAGDIRPPAPEDVGRRTTTVGRTPPGRNRRLRELITEASDPPVICLKGGHNQLKCLRYRLKSKHSSLFDCISTTWSWVDTTSTCRLGSGRMLIKFADSEQRDKFLSRVPLPSTTQVFLGNFYGL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RS17_STRM5
Sequence: MSDNTENKALRTVEGRVVSNKMDKTVTVLVERQVKHALYGKYIKRSTKLHAHDADNACKEGDVVRVTEIAPMSKTKNWRVVEVITRAAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ETS_NPVAC
Sequence: MMERTVTRWHLVSDNVLFKIGEVAQRLDYYLQEYANLEMQIEEEIKYMEVDDGEEIDTIKTFLRNSMSTSEQRDLYALALKLNSLINK
What are the official names of this protein?
Uncharacterized protein ETS, ECORI-T site protein.