PharMolix/UniProtQA huggingface dataset:
Protein: SP27A_DROME
Sequence: MTKMGGNLAVMLLSLFLSALATGNGNSIPTTTTPQGVFETRTDKLPGGAASVPSGAGIYDDIDTFVPFRSDSHDPFSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELANTQTDIRSQNNVREFYRKTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTNPEAAADAINAWAANITQGRLQQLVAPDNVRSSVMLLTNLIYFNGLWRRQFATTFQGSFFRSKDDQSRAEFMEQTDYFYYTTSEKLKAQILRLPYKGKNSLFVLLPYALNGIHDLVKNLENDELKSAQWAMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRGADVAGKVKVSNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHSPTTQN
What is the function of this protein?
Serine protease inhibitor that functions in embryonic dorsoventral patterning and the melanization immune response (PubMed:14654000, PubMed:14667416, PubMed:12408809, PubMed:12456640, PubMed:16861233, PubMed:16322759, PubMed:18801354, PubMed:22227521, PubMed:24260243, PubMed:24788090).  Regulates dorsoventral axis formation during early development by inhibiting the serine protease easter, and is therefore important for restricting activity of the Toll signaling pathway to the ventral part of the embryo (PubMed:14654000, PubMed:14667416).  Also plays an essential role in the melanization immune response to both physical wounding and septic infection using certain bacteria and fungi (PubMed:12408809, PubMed:12456640, PubMed:18801354, PubMed:22227521).  Negatively regulates the Hayan-dependent prophenoloxidase 1 (PPO1)-activating cascade in the hemolymph by inhibiting the serine proteases MP1 and Sp7 (PubMed:12408809, PubMed:12456640, PubMed:16861233, PubMed:16322759, PubMed:18801354, PubMed:22227521, PubMed:24260243, PubMed:24788090).  May be involved in negatively regulating the melanotic encapsulation around eggs of the parasite L.  boulardi (PubMed:12408809, PubMed:15749104).
What are the official names of this protein?
Serine protease inhibitor 27A, Serpin 27A.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the hemolymph (PubMed:12456640). Detected in the perivitelline fluid of embryos (PubMed:14667416).
Protein: MDM34_CRYNB
Sequence: MSFVFPSWSTAFSPAFHEDAKAMLEGALNKGDKPPVIQGKIEVVELHMGEQPPTLTLLEIGDLSIDRFRGILRLGYQGDAWLEVRCRVQANPLSHNPHLTFSTLPLSTPLLASQPLLVPMTLRLSKLHLRAILILVVSASKGITLVFKNDPLQNVDVSSTFDSVEVIRGYLQQEIEGQLREMFREHLPGIIHRLSQKWFSGSGVGGKVEMPYRDMSPVPSYAPINEEVEEEENEENHGTSPGNEESFPPRHIGPGGITLPLNNSVSQLAALSYSAHTLSPYARGHEHIAVRSFPYLGKSGAGTGSSGRASLASSSVGEGDIKAKRKRIFRIGKSKEADEKSEA
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: D9_RFVKA
Sequence: MTTFETPRETVFIESVDSIPQSKKTHVFAICVTVDNKPIVAARRSSFVFQEITMNMNPPIVVTISKHLTNYMYNNEIKEIKRKLQKGSAPIYKTSFEELILLGGKLNKSETIDDCIRREIKEETDSKLTIKSIGTTCVKITITDKLFNRKYVNYCKLCYIDELMEEVISFVIYNVEIRKLKSLLDCDNNDKFNYLRFIYNTLLYSK
What is the function of this protein?
Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells.  May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins.  Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis.  Does not cleave unmethylated RNAs or RNAs shorter than 24 nucleotides (By similarity).
What are the official names of this protein?
mRNA-decapping protein D9.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: Y1146_ANASK
Sequence: MAWARDEGGAAVLELLVQPRASRTRAVGEHDGRLKIQLAAPPVDGAANAALVEFLAVALGVRRADVALLRGETGRRKTVRVAGITAAAAVAALAS
What are the official names of this protein?
UPF0235 protein AnaeK_1146.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: YR383_MIMIV
Sequence: MKPIIFSLPRVINNESIPPPINKSKIYFDDNPSPKLIKYGFNNISEKMDLNILTSDSHYKAGLNIDFTRDDKNSFVSKTAEIFGNQYDPAFYQAWEILNIFDLINKSESIYTNIPETLLEVTNSHKKLFKTNKQYNITNDINKAINIQLIYSRYSDIDIDENALIQLIYNDLSSLFQMQIQGSNMILQLFNVQTQVTVQLIYLLSSYYTEAYLYKPESSSDLSDNKYLILIGLRNKSTIDLPKFPSNRYLLSLGVNDIPNNFTSVIQCMNSFVMPNKYETYLKIINYLNTKVYEGATYQDLIKEQNKFTLDWINIFTEPDKIKTILDDSINFVDKNCANSSKLDELFS
What are the official names of this protein?
Uncharacterized protein R383.
What are the subcellular locations of this protein?
Virion.
Protein: PSAJ_NICSY
Sequence: MRDLKTYLSVAPVLSTLWFGALAGLLIEINRFFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DNLJ_NITMU
Sequence: MSERLSEISRHMRELRDAIELHNIRYYELDTPTIPDADFDKLFRELEELEQRHPELITPDSPTQRVGIPPLKAFPQVVHRTPMLSLSNAFTEGEVEAFDRRVRQSLGIAQVEYAVEPKFDGLAISLCYENGMLVSGATRGDGYIGEDVTLNLKTIRSIPLGLRAGDGSAEVPAFLEVRGEVLMLKADFERLNRQQREKNEKTFINPRNAAAGSLRQLDPCITANRNLRFFAYGIGVCEGGNVPHDTHSHLLDYLSSLRFPVMRERRTVTGVAGLLEYHHEINGLREQLSYDIDGTVYKVNELEYQEKLGFVSRAPRFALAHKFPAQEATTELLGIDVQVGRTGALTPVARLKPVFVGGATVTNATLHNEDEIRRKDVMIGDRVTVRRAGDVIPEVVAVQKESRPSNAKPFVMPEHCPVCGSRTIRLPGETLTRCTGGLFCPAQRKQAILHFASRRAMNIHGLGDKLVDHLVDNAIIRTPADLYKLGLAALAALDRMGEKSAGNIINEIEKSKDTTLARFIYSLGIRNVGEATARDLARYFGGLDRLMDADVETLQQVSDVGPVVAQSIADFFGERHNREVVEQLRAAGIRWKEGAGTQTTDHAAGSAHPGAAAASSKIAGRSFVLTGTLPTMSREEAREKIEAMGGKVAGSVSKKTDYVVAGADAGSKYDKALELGVALLDEAELIRLLQASQADNSSTHVDPERMV
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL4_LACP3
Sequence: MANVTLYKQDGSENGKVELNDAIWAVEPNENVVFDAVVMQRDSLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGIVFGPTPRSYAYKLPKKVRRLAIKSVLSQKVLDSDLVVVDGLNFDAPKTKAFATVLDGLKVSDKALVVLEDGNEVAAKAARNLPNVKVVPAEGINVLDVVDYKKLILTQSALQKIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS5_SHEDO
Sequence: MAKLEAQQKDDLQEKLIAVNRVSKVVKGGRIFSFTALTVVGDGNGKIGYGYGKAREVPAAIQKAMEKARRNMVTVELNAGTLHHPVKGRHTGSKVYMQPASQGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALVHMKSPAQIAAKRGLNVDEIRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CRCB1_BACCZ
Sequence: MRKLIYIMVGIAGILGALSRYYLGLTIHEFWHHTFPLATLLINLAGCFLLAWLTTYIAKLNILPSDVITGIGTGFIGSFTTFSTFSVETIQLINHFEWGIAFLYVSCSILGGLIMSGLGYTLGDFLLKKHLTEGDHL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CP33_ARATH
Sequence: MSSAYCSSAVAVSAAATASSAATFNPLLSSHSNSQLFYRFTPKSFKLVANCPNPLILHSNIRRHRFFCAAETEASSADDEIQASVEEEEEVEEEGDEGEEEVEEEKQTTQASGEEGRLYVGNLPYTITSSELSQIFGEAGTVVDVQIVYDKVTDRSRGFGFVTMGSIEEAKEAMQMFNSSQIGGRTVKVNFPEVPRGGENEVMRTKIRDNNRSYVDSPHKVYAGNLGWNLTSQGLKDAFGDQPGVLGAKVIYERNTGRSRGFGFISFESAENVQSALATMNGVEVEGRALRLNLASEREKPTVSPPSVEEGETEEASLESNEVLSNVSA
What is the function of this protein?
Could be involved in splicing and/or processing of chloroplast RNAs.
What are the official names of this protein?
RNA-binding protein CP33, chloroplastic, Protein PIGMENT DEFECTIVE 322.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL3_BACHK
Sequence: MTKGILGRKIGMTQVFAENGELIPVTVIAANPNVVLQKKTTETDGYNAIQLGFEDKREKLTNKPEQGHTAKASTTPKRFIREIRDADVDGLEVGQEVKVDVFATGEIVDVTGISKGKGFQGVIKRHGQSRGPMSHGSRYHRRPGSMGPVAPNRVFKGKKLAGRMGGDQVTIQNLEIVQVDTERNLLLVKGNVPGAKKSLVVVQGAVKVSK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YAAI_SALCH
Sequence: MRSVLTISASLLFGLALSSVAHANDHKILGVIAMPRNETNDLTLKIPVCRIVKRIQLTADHGDIELSGASVYFKTARSASQSLNVPSSIKEGQTTGWININSDNDNKRCVSKITFSGHTVNSSDMARLKVIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: RUVB_SYNS9
Sequence: MAIVSSSSGRKSPCRETALVDPQPAPEEQVIRPEDSLRPKRLSEYIGQSELKQVLGIAVEAALGRGEALDHVLLYGPPGLGKTTMALVLAEELGVNCRITSAPALERPRDIVGLLVNLQPRDLLFIDEIHRLSRVAEELLYPAMEDRRLDLTVGKGSTARTRTLDLPPFTLVGATTRAGSLSSPLRDRFGLIQRLEFYGQTDLEAIVARTAELVSVDLTFDACARIAASCRGTPRIANRLLRRVRDVASVRQGKGTIDDAMVAEALSLHRVDHRGLDASDRRLLAMLMDQHGGGPVGLETLAAALGEDPVTLETVVEPFLLQQGLLVRTPRGRMVTDAARSHIAEAA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CTAA_LISIN
Sequence: MKKFLKVWSVLTIICMTVVVFGGALVTKTGSADGCGNSWPLCNGQLVRLTDVTPEKLIEFMHRMTTGISSIFVIVLAICAWIYMKNRRETKPLAIIAVLFLIIQALMGMAAVVWGQNPYIMALHFGISIICYASIVLLALMIFEVDRKFDARNLVMGTKLRINIYALTIYTYLAVYTGALVRHEKASMAVPVWPFENGHFIMPTSVQDYVQYFHRLAAFILIVWLLYVTWLVFRDYRRYRVLTFSMVLSLVFIALQAVTGALSVYTGVNLYIALAHSLIITMLFALLCYLCLLASRSKSNRLRIK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_BURM9
Sequence: MDMQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKSVFLGHPAPNAPEAAILSTCNRTELYCATNDRAARDAAIRWMSDYHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKNAVRTASEAGSLGTYLNQLFQRTFAVAKEVRGTTEIGAQSVSMAAAAVRLAQRIFEQVAQQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGAKLAERFGGRAMPLADLPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADALRRAEVERARKMLARGDDPDAVLDALSQALTNKLIHGPTSALNRANGADRDSLIDLMRGFYQHAPRSSDTSDR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CENPK_CHICK
Sequence: MSDSVCPIDAKEELLRECENIWKEMEKCQSKLTLLAAEPVPESDAKVSLLLTRMQALRAEYHQWQKRNPELISTNPEVLLLLGEEELQKVKKELEMVLSAVQLKNEKLKEDLEREQQWHDEQVQILNAFKEIEEEMKKEVVTDSEKRVFQELKNQMLELKEYKKKLMNALGEFLEEHFPLPEKNGNAKKKRYSEEPPEQVITIHEILEILLNQLMSTPHEPYVTVDDSFWPPYLELLLRSGIVLRHPEDPNRIRLEAFHE
What is the function of this protein?
Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.
What are the official names of this protein?
Centromere protein K, CENP-K.
What is the protein family that this protein belongs to?
Belongs to the CENP-K/MCM22 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the centromeres.
Protein: CYB_CAPNU
Sequence: MTNIRKTHPLMKIVNNAFIDLPTPPNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLLTTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDTDKIPFHPYYTIKDILGIMLLILVLMLLVLFTPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLVPFLHTSKQRSMMFRPISQCMFWILAADLLTLTWIGGQPVEHPYIIIGQLASIMYFLIILVMMPAASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CD5R2_HUMAN
Sequence: MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVYLLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRLIQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKHWTMNLDR
What is the function of this protein?
Activator of CDK5/TPKII.
What are the official names of this protein?
Cyclin-dependent kinase 5 activator 2, CDK5 activator 2, Cyclin-dependent kinase 5 regulatory subunit 2, p39, p39I.
What is the protein family that this protein belongs to?
Belongs to the cyclin-dependent kinase 5 activator family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: GPH_AGRFC
Sequence: MTSRPLSPLAIFDLDGTLVDTAADLVSSLNHTIAAAGLAPVTYDDLTHLVGQGARVMIKRAFALRETELPEADIDPLYERFITHYRAEMPGESRPYPGIIETLDALSQAGITLAVCTNKTEILAVPLLEKLGLTRYFAAITCGDTFAFRKPDARHILGTIEKAGGDVQRSIMVGDSINDILAARNAAVPSIGVTFGYTDVPMVELEPDVVIDDFAALTPALFEKLVSKGAAAA
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: AROA_SULDN
Sequence: MSSVKVYKALAFSLRTSEIASDKSISHRCAMFAMLADGTSQITNFLRAEDTMNSLKIVKNLGATIDDDGETIKISSDGIKESSEVLDCGNSGTGMRLFCGLLSSADGHFVLSGDEYLRRRPMKRITAPLRDIGAKLDGRENGDLAPLSIRGASLKAFNYESKIASAQVKSAMILAALRADGECSFSEPELSRDHTERMLKGMGAEIEVEGLITKIKPMKKLLSPLKIRVPADPSSAFFFAVAAAITPNSNVVLEGVTLNPTRIEAFKALERMGADIRYEATENIYEPIGNIHVKYAPLKAITVEDNISWLIDELPALSIAFACADGVSIVKNAQELRVKESDRISTVVNGLKACGIEVDEVHDGYSVKGGVLKEAKIDSHGDHRIAMSFIIAGVTCGMRVDDIACINTSFPNFFELLKKITKVEFTSL
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_AMECE
Sequence: MTNIGKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTELVQWIWGGFSVDKATLTRFFAFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSTLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHMSKQRSMMFRPLSQCLFWLLVAILFTLTWIGGQPVEHPYIIIGQTASILYFLIILIFMPATSLMENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS8_SULDN
Sequence: MINDLVSDALTRIRNAGMRRLDVTTLVHSKSVEALANILVEKGYIESCNVVEDGVKKTINVVLKYSDNGKSVINEMKRISKPGRRVYKGKDEIKRFKNGYGTIIVSTSHGVLPNDKAYALGVGGEVMCTVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: FRHG_METJA
Sequence: MIKVVKVAHVQLCSCCGCLVSLADTYEKLLDVLNSIELVYCQTLADAREIPECDIALVEGSVCLDDHHSLEVAQEVRKKAKIVVALGACAATGGVTRYCKGNQLSKPVHSSFSPLTEVIKVDLAIPGCPPSPEAIVGVITAALNGDMEYLQPYAELAEKGSEACGCDVIYKVVNKSLCMGCGTCAAACPTRAIEMLDGRPNVLKELCIKCGACSVQCPRIRFPELIEKIE
What is the function of this protein?
Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
What are the official names of this protein?
Coenzyme F420 hydrogenase subunit gamma, 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma, FRH.
What is the protein family that this protein belongs to?
Belongs to the FrhG family.
Protein: RPOY_BACSU
Sequence: MIYKVFYQEKADEVPVREKTDSLYIEGVSERDVRTKLKEKKFNIEFITPVDGAFLEYEQQSENFKVLEL
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP) (PubMed:6802805, PubMed:18289874, PubMed:21710567, PubMed:25092033).  Has a similar structure to bacteriophage T7 protein Gp2 (AC P03704), which is known to bind to RNAP in the DNA binding-cleft.  Unlike Gp2 however, this protein does not inhibit transcription initiation (PubMed:25092033).  In vitro reconstitution experiments show this subunit is dispensible (PubMed:18289874).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, DNA-directed RNA polymerase subunit omega 1, RNA polymerase epsilon subunit, RNA polymerase omega 1 subunit, Transcriptase subunit epsilon, Transcriptase subunit omega 1.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Colocalizes with RNAP.
Protein: ODO1_ECOL6
Sequence: MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALNVE
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: SYY_LEGPL
Sequence: MIVQDSVCSELMRGCEEILPVPELEKKLQKGIPLKIKAGFDPTAPDLHLGHTVLLNKLRQFQQFGHEVIFLIGDFTAMIGDPTGKNVTRMPLSQETVLENAKTYQHQVFKILDPDKTTVAFNSQWLNKFNAVDLIRLAATHTVARMLERDDFNKRYTTGQPIAIHEFLYPLLQGYDSVALKADVELGGTDQKFNLLMGRELQKHYGFEPQVVMMTPLIEGLDGVKKMSKSLDNYIGINETSEQMFGKIMSVSDELMWRYIDLLSFKTGKEIQQLKQSVLEGKNPRDVKIDFAKEIVARFHDQTQAEFAHNKFIERFQKGNIPEDLEELSLVIAEPIALAQLLKQIDLTASTSESIRMVKQGAVKVDGDKISDPSLKLPIGKSYIIQVGKRRIAKLSIQQAH
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.