PharMolix/UniProtQA huggingface dataset:
Protein: GRNL6_PERFR
Sequence: MSSISQKVVIGLNKAAANNNLQNLDRRGFKTRCVSSSKAASCLRASCSLQLDVKPVQEGRRSGNYQPSIWDFNYVQSLNTPYKEERYLTRHAELIVQVKPLLEKKMEAAQQLELIDDLNNLGLSYFFQDRIKQILSFIYDENQCFHSNINDQAEKRDLYFTALGFRILRQHGFDVSQEVFDCFKNDSGSDFKASLSDNTKGLLQLYEASFLVREGEDTLEQARQFATKFLRRKLDEIDDNHLLSCIHHSLEIPLHWRIQRLEARWFLDAYATRHDMNPVILELAKLDFNIIQATHQEELKDVSRWWQNTRLAEKLPFVRDRLVESYFWAIALFEPHQYGYQRRVAAKIITLATSIDDVYDIYGTLDELQLFTDNFRRWDTESLGRLPYSMQLFYMVIHNFVSELAYEILKEKGFIVIPYLQRSWVDLAESFLKEANWYYSGYTPSLEEYIDNGSISIGAVAVLSQVYFTLANSIEKPKIESMYKYHHILRLSGLLVRLHDDLGTSLFEKKRGDVPKAVEICMKERNVTEEEAEEHVKYLIREAWKEMNTATTAAGCPFMDELNVAAANLGRAAQFVYLDGDGHGVQHSKIHQQMGGLMFEPYV
What is the function of this protein?
Monoterpene synthase (mono-TPS) involved in the biosynthesis of monoterpenes natural products (PubMed:17187833).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) into geraniol (PubMed:17187833).
What are the official names of this protein?
Geraniol synthase, chloroplastic, PfTps-PL.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YIDD_CHLMU
Sequence: MKTSWIKIFFQGMIHLYRWTISPLLGSPCRFFPSCSEYALVALKKHPLKRSLFLIANRLLKCGPWHIGGIDLVPGTSIEEYLESPDDKNVPPDQETV
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CHD9N_HUMAN
Sequence: MGCHSSKSTTVAAESQKLEEEREGREPGLETGTQAADCKDAPLKDGTPEPKS
What are the official names of this protein?
CHD9 neighbor protein.
Protein: RL14_AERPE
Sequence: MAKKKKYGVVVSRYGVNTGLQVGSYVPVADNSGAKEVMIISVPQVKTRLRRLPSAGVGDLVVVSVKKGTPQMRRQVVYAVVVRQRRPFRRPDGTWVSFEDNAVVIVNPDGTPRGSEVRGPIAREAAERWPRVAKIATMIV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HIS8_STAA2
Sequence: MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SLMA_ECOLI
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLASQILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA, Protein Ttk, Synthetically lethal with a defective Min system protein A.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RAB3A_RAT
Sequence: MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQAPPHQDCAC
What is the function of this protein?
Small GTP-binding protein that plays a central role in regulated exocytosis and secretion.  Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (PubMed:21689256).  Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (PubMed:18407218).  Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (PubMed:17149709).  Stimulates insulin secretion through interaction with RIMS2 and RPH3AL effectors in pancreatic beta cells (By similarity).  Regulates calcium-dependent lysosome exocytosis and plasma membrane repair (PMR) via the interaction with 2 effectors, SYTL4 and myosin-9/MYH9 (By similarity).  Acts as a positive regulator of acrosome content secretion in sperm cells by interacting with RIMS1 (By similarity).  Plays a role in the regulation of dopamine release by interacting with synaptotagmin I/SYT (PubMed:28057568).  Interacts with MADD (via uDENN domain); the GTP-bound form is preferred for interaction (By similarity).
What are the official names of this protein?
Ras-related protein Rab-3A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Lysosome. Cytoplasmic vesicle, secretory vesicle. Cell projection, axon. Cell membrane; Lipid- anchor; Cytoplasmic side. Presynapse. Postsynapse. Note=Cycles between a vesicle- associated GTP-bound form and a cytosolic GDP-bound form.
Protein: YBEY_STRPQ
Sequence: MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVTNERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAYGLTRQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HERIN_HERER
Sequence: VPSSFRTTITDAQLRG
What is the function of this protein?
Metalloprotease which hydrolyzes the alpha and gamma chains of fibrinogen.  No activity against fibrinogen beta chains.  Active against the synthetic tissue plasminogen activator substrate H-D-Ile-Pro-Arg-PNA and the synthetic plasmin substrate H-D-Val-Leu-Lys-pNA.
What are the official names of this protein?
Herinase.
Protein: DYM_CHICK
Sequence: MGANSSSISELPDNEYLKKLSGAEPISENDPFWNQLLSFSFTTPTNSADLKLLEEATVSVCKSLVEKNPRTGNLGSLIKVFLSRTKELKISAECQNHLFIWQAHNALFIICCLLKVFISRMSEEELQLHFTYEDKTPGSYGTECEDLIEELLCCLIQLIVEIPLLDITYSISLEAVTTLIVFLSCQLFHKEILRESLIHKYLMRGRCLPYTSRLVKTLLYNFIRQERSPPPGSHVFQQQTDGGGLLYGIASGVATGLWTVFTLGGVGSKATPQLDQCSPLANQSLLLLLVLANLTDAPDTPNPYRQAIMSFKNTQDSSAFSSSHPHVFQINFNSLYTALCEQQKSDQATLLLYMLLHQNGNVRTYVLARTDIENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYAERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLDSNDSPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLEHAGAELSVERVLEIIKQGAVALPKDRLRKFPELKFKYVEEEQPEEFFIPYVWSLVYNAAVALYWNPRDIQLFTMDSG
What is the function of this protein?
Necessary for correct organization of Golgi apparatus.
What are the official names of this protein?
Dymeclin.
What is the protein family that this protein belongs to?
Belongs to the dymeclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Note=Sequence analysis programs predict 1 transmembrane region. However, it has been shown in human that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol (By similarity).
Protein: CEBPB_CHICK
Sequence: MQRLVAWDAACLPIQPPAFKSMEVANFYYEADCLAALNKLHPRAAGGRSMTELTVGDHERAIDFSPYLDPLAASQQPAQPPPPAAAAGGNFEPACSSGGQDFLSDLFAEDYKGSGGGKKPDYTYISLTRHGHPCGSQSHKPGVLPGCFPPQIVETKVEPVFETLDSCKGPRKEEGGAGPGPGGMSSPYGSTVRSYLGYQSVPSGSSGNLSTSSSSSPPGTPNPSESSKSAAGAGGYSGPPAGKNKPKKCVDKHSDEYKLRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASSPRC
What is the function of this protein?
Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:8467792).  Also plays a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis.  The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'.  Its functional capacity is governed by protein interactions and post-translational protein modifications.
What are the official names of this protein?
CCAAT/enhancer-binding protein beta, C/EBP beta, Transcription factor NF-M, CCR protein.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. C/EBP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDUS3_PROWI
Sequence: MNNNFEKSILLMVPQWIQYHVSHRNETTFYVYPEYLKPFLYFLRDHMSTQYKVCIDITAADYPSRASRFECVYNLLSVEYNSRIRIKTCVDEITTLESVTPVYSSAAWWEREVWDMFGVFFHNHPDLRRILTDYGFQGHPLRKDFPLSGYVEVRYDDSEKRVCIESVEYSQEFRYFDFESPWEQVDKNSLLK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase subunit 9.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Note=Matrix and cytoplasmic side of the mitochondrial inner membrane.
Protein: RL23_ENTFA
Sequence: MELLDVIKRPVITEKSMLAMDEKKYTFEVDTRANKTLVKQAVESAFDVKVANVNILNVRPKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: GLMU_HELHP
Sequence: MNVSVVILAAGAGTRMKSHIPKVLHKICGKEMLFYSIDEALKISDDVHIVLFHQENVIKERLLCAYKQAYADGALHFHLQDHAHYPGTGGALMQGQNAGANAKKPFCYQYDEILILNGDMPLVCSQTLKSLCQNKAQIVMSVLHLQNPDGYGRVVMESGVVQRIIEQKDAKESELLIKDVNAGVYKIHKSILDLYLPQVGNANNQQEFYLTDVVFYAKENGIEIAALEVKEEEFMGVNSKIQLACAQEIMLQRLREKAMEQGVIMNLPHTIYLESNVTFSGECIIEQGVQILGDSHISDSHIKAHSVIEQSIIESSDVGPLAHIRPKSHIKNTHIGNFVETKSSTLRGVKVGHLSYLGDCEIDEGSNIGAGVITCNYDGKAKHKTTIGKSVFVGSDVQLIAPLNIESNVLIGAGSTITKDIEYGDLALSRVAQQNIKDGFFKFFSDKNEEKKEQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTH_CHICK
Sequence: MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ZG71_XENLA
Sequence: TGEKPFSCSTCGKCFLDRSHLTRHQRIHTREKPFSCSVCKKCFLDQSSLTRHQLIHTADKNFSCLECEKCFSKQSSLVSHQRTHTGEKPFSCSECDKCFAFSSELIVHQRTHTGEKPFSCSECEKCFSKQSSLTRHQMIH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Gastrula zinc finger protein XlCGF71.1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPCE_PIG
Sequence: MLSFQYPDVYRDETAIQDYHGHKVCDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNAYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRLINIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLKIFPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIP
What is the function of this protein?
Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
What are the official names of this protein?
Prolyl endopeptidase, PE, Post-proline cleaving enzyme.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_SYNPW
Sequence: MQIIPAIDLLGGSCVRLHQGDYDKVTRFSDDPVAQALQWQEQGAERLHLVDLDGARTGEPANDSAIRAITSALTIPVQLGGGVRTAERADTLLACGLDRVILGTVALEQPQLVVELADRHPGRVVVGIDARHGKVATKGWIEDSNTEATALAQRFSASAIAAIISTDISTDGTLEGPNLQALREMAEASSVPVIASGGVGCMGDLLALLTLEPLGVEAVIVGRALYDGRIDLGEARKALAESRLQDPPSDLLQDFA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_NITOC
Sequence: MIGRLRGILLEKRAPFLLLDVQGVGYELEAPLSTFYVLPAMGAEVILYTHLVVRDDAHLLYAFASEKERGLFRSLIRVNGVGAKLGLGILSGIEAESFTRCVQEGDTVSLTRLPGVGKKTAERLIVEMRDRLLDMPESGVAGMRPDRVDGSAPGTVAEAVSALVALGYKPNEASRAVRRLDTEALTTEEIIRQALQRML
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: GPDA_BURM7
Sequence: MLSMKVAVLGAGAWGTALAAHLAVRHDTLLWARDAALVAELAARRENARYLGGVALPPGLRYEADLATALSHAQADDALCVIAAPVAGLRALCRAMRDARRVPAHFVWVCKGFEADTRRLPHQMVAEELPDHASYGVLSGPSFAREVAQGLPVALTVASASAACRERTLAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALVTRGLAEMSRLGVALGGRAETFTGLTGLGDLILTATGDLSRNRSVGLQLAAGRSLDDILAALGHVAEGVRCARAVLSIARERGVDMPITEAVCAVLFDGVAPRDAVSGLLRRDAKAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_CHLCV
Sequence: MAPKKTTKKGGPQKRPSAEKRILTAQKRYLINQSFKSKAKTMMKKFEAALKAGDQSSITSGLQLVYSVADKAVKRGIFKNNKAARIKSRATLRANVKI
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: TYSY_TERTT
Sequence: MKQYLELMRHVRDNGVRKEDRTGTGTVSVFGYQMRFDLSQGFPLVTTKKCHLKSIIHELLWFLNGETNIAYLNNNGVKIWDAWATESGDLGPIYGAQWRSWPAQNGETLDQISQLIEQIKHKPDSRRLIISAWNPALLPDESISPQDNVRNGKMALPPCHTLFQFYVLEGRLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLAPGDFVHTFGDAHLYLNHLEQVDTQLQRQPLPLPTMAINPAVKDIFGFCFDDFELQNYQAHPHIAAPISV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIN3_ORYSJ
Sequence: MGIAEVALHSMPGAFAAHSPASNLPLAADAARGRRRRSANSLHSSRALQGPVRFPGLRAAVECQCQRIDDLARVTEGNGAWVKDAVDKASHALGDVRVPGQAVGGNGSVNGSAAKPPPQRRKASSVEDEAWELLRESVVYYCGSPVGTIAANDPNDANPMNYDQVFIRDFIPSGIAFLLKGEYEIVRNFILHTLQLQSWEKTMDCHSPGQGLMPASFKVRTIPLDGDEDATEEVLDPDFGEAAIGRVAPVDSGLWWIILLRAYGKCSGDLTVQERIDVQTGIKMILKLCLADGFDMFPTLLVTDGSCMIDRRMGIHGHPLEIQALFYSALLCAREMLTPEDGSADLIRALNNRLIALSFHIREYYWVDMQKLNEIYRYKTEEYSYDAVNKFNIYPDQVSPWLVEWIPPKGGYFIGNLQPAHMDFRFFSLGNLWSIVSSLATTHQSHAILDLIESKWSDLVAEMPLKICYPALENQEWKIITGSDPKNTPWSYHNGGSWPTLLWQLTVASIKMNRPEIAAKAVEVAERRIAIDKWPEYYDTKRARFIGKQSRLYQTWSIAGYLVAKQLLDKPDAARILSNDEDSEILNALSTNRKRGKKVLKKTFIV
What is the function of this protein?
Mitochondrial invertase that cleaves sucrose into glucose and fructose.
What are the official names of this protein?
Neutral/alkaline invertase 3, chloroplastic, OsNIN3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 100 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TIAR_HUMAN
Sequence: MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ
What is the function of this protein?
RNA-binding protein involved in alternative pre-RNA splicing and in cytoplasmic stress granules formation (PubMed:1326761, PubMed:8576255, PubMed:17488725, PubMed:10613902).  Shows a preference for uridine-rich RNAs (PubMed:8576255).  Activates splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on its own pre-mRNA and on TIA1 mRNA (By similarity).  Promotes the inclusion of TIA1 exon 5 to give rise to the long isoform (isoform a) of TIA1 (PubMed:17488725).  Acts downstream of the stress-induced phosphorylation of EIF2S1/EIF2A to promote the recruitment of untranslated mRNAs to cytoplasmic stress granules (SG) (PubMed:10613902).  Possesses nucleolytic activity against cytotoxic lymphocyte target cells (PubMed:1326761).  May be involved in apoptosis (PubMed:1326761).
What are the official names of this protein?
Nucleolysin TIAR, TIA-1-related protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytolytic granule. Cytoplasm, Stress granule. Note=Nuclear import seems to be coupled to RNA polymerase II transcription and may be dependent on RNA-binding (By similarity). Accumulates in cytoplasmic stress granules (SG) following cellular damage (PubMed:10613902).
Protein: LHX5_DANRE
Sequence: MMVHCAGCERPILDRFLLNVLDRAWHAKCVQCCECNCNLTEKCFSRDGKLYCKIDFFRRFGTKCAGCLQGISPSDLVRRARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKEDYLSASAIKEVNLNSVSSCTDRSLSPDLPDQIQDDTKETDNSTSSDKDTNNNENEEQNSCTKRRGPRTTIKAKQLETLKAAFVATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRGPRRMRPLGGRLEDPDIMGPGGYSYYGEYQGDYYGPVVNYDFFPHGPPSSQAHSPAESPYLLSSGSGALEGGPVSAHHPSDDQRFTDMISHADTPSPEPGMTGPLHSNPQGEGGFTGSPPFPLANNTSYSGPMSHPGQEMGENTVW
What is the function of this protein?
Probably involved in the patterning of the nervous system, in particular in the early specification of the diencephalon.
What are the official names of this protein?
LIM/homeobox protein Lhx5, LIM homeobox protein 5, Homeobox protein LIM-5.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPA_STAAW
Sequence: MEIILFLTMMVMITYVFSGYLYRVALVQSSRVDLIFTRFENMCFKIIGTDLEHMSAKTYVKHFLAFNGFMGFITFVLLIVQQWLFLNPNHNLNQSIDLAFNTAISFLTNSNLQHYNGESDVTYLTQMIVMTYLMFTSSASGYAVCIAMLRRLTGLTNIIGNFYQDIVRFIVRVLLPLSCLISILLMTQGVPQTLHANLMIRTLSGHIQHIAFGPIASLESIKHLGTNGGGFLAGNSATPFENPNIWSNFIEMGSMMLLPMSMLFLFGRMLSRHGKRVHRHALILFVAMFFIFIAILTLTMWSEYRGNPILANLGIYGPNMEGKEVRFGAGLSALFTVITTAFTTGSVNNMHDSLTPLGGLGPMVLMMLNVVFGGEGVGLMNLLIYVLLTVFICSLMVGKTPEYLNMPIGAREMKCIVLVFLIHPILILVFSALAFMIPGASESITNPSFHGISQVMYEMTSAAANNGSGFEGLKDDTTFWNISTGIIMLLSRYIPIILQLMIASSLVNKKSYHQDKYTIAIDKPYFGVSLIVFIVLLSGLTFIPVLLLGPIGEFLTLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYR_MYCBP
Sequence: MTPADLAELLKATAAAVLAERGLDASALPQMVTVERPRIPEHGDYASNLAMQLAKKVGTNPRELAGWLAEALTKVDGIASAEVAGPGFINMRLETAAQAKVVTSVIDAGHSYGHSLLLAGRKVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLTTQGADVVREYYFNDHGAQIDRFANSLIAAAKGEPTPQDGYAGSYITNIAEQVLQKAPDALSLPDAELRETFRAIGVDLMFDHIKQSLHEFGTDFDVYTHEDSMHTGGRVENAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVLTLDDLVEAIGVDAARYSLIRSSVDTAIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLNHDKEGTLLRTLGEFPRVLETAASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAIIGVTAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.