PharMolix/UniProtQA huggingface dataset:
Protein: PIKS1_ORYSJ
Sequence: MEAAAMAVTAATGALAPVLVKLAALLDDGECNLLEGSRSDAEFIRSELEAVHSLLTPNILGRMGDDDAACKDGLIAEVRELSYDLDDAVDDFLELNFEQRRSASPFGELKARVEERVSNRFSDWKLPAASLPPSSVHRRAGLPPPDAGLVGMHKRKEELIELLEQGSSDASRWRKRKPHVPLRIMGGEMQKIVFKIPMVDDKSRTKAMSLVASTVGVHSVAIAGDLRDEVVVVGDGIDSINLVSALRKKVGPAMFLEVSQAKEDVKEITAMLAPVKSICEFHEVKTICILGLPGGGKTTIARVLYHALGTQFQCRVFASISPSSSPSPNLTETLADIFAQAQLGVTDTLSTPYGGSGTGRALQQHLIDNISAFLLNKKYLIVIDDIWHWEEWEVIRKSIPKNDLGGRIIMTTRLNSIAEKCHTDDNDVFVYEVGDLDNNDAWSLSWGIATKSGAGNRIGTGEDNSCYDIVNMCYGMPLALIWLSSALVGEIEELGGAEVKKCRDLRHIEDGILDIPSLQPLAESLCLGYNHLPLYLRTLLLYCSAYHWSNRIERGRLVRRWIAEGFVSEEKEAEGYFGELINRGWITQHGDNNSYNYYEIHPVMLAFLRCKSKEYNFLTCLGLGSDTSTSASSPRLIRRLSLQGGYPVDCLSSMSMDVSHTCSLVVLGDVARPKGIPFYMFKRLRVLDLEDNKDIQDSHLQGICEQLSLRVRYLGLKGTRIRKLPQEMRKLKHLEILYVGSTRISELPQEIGELKHLRILDVRNTDITELPLQIRELQHLHTLDVRNTPISELPPQVGKLQNLKIMCVRSTGVRELPKEIGELNHLQTLDVRNTRVRELPWQAGQISQSLRVLAGDSGDGVRLPEGVCEALINGIPGATRAKCREVLSIAIIDRFGPPLVGIFKVPGSHMRIPKMIKDHFRVLSCLDIRLCHKLEDDDQKFLAEMPNLQTLVLRFEALPRQPITINGTGFQMLESFRVDSRVPRIAFHEDAMPNLKLLEFKFYAGPASNDAIGITNLKSLQKVVFRCSPWYKSDAPGISATIDVVKKEAEEHPNRPITLLINAGYKEISTESHGSSENIAGSSGIDTEPAQAQHDNLPAVRDDYKGKGILLDGRCPTCGRATKIEEETQDRVADIEIQTETTS
What is the function of this protein?
Disease resistance (R) protein that specifically recognizes the AVR-Pik effector avirulence protein from M. oryzae.  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein.  That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
What are the official names of this protein?
Disease resistance protein Piks-1, NBS-LRR class disease resistance protein Piks-1.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: CYB_THAIM
Sequence: MAPNLRKSHPLLKMINNSLIDLPTPSNISAWWNFGSLLGICLMTQILTGLLLAMHYTADTTLAFSSIAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLNKETWNTGILLLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTLIHLTFLHESGSNNPLGILSNCDKIPFHPYFTLKDILGFTLMFLPLTALALFSPTLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLSPLLHKSKQRTLTFRPLSQLLFWLLVTNLFILTWIGSQPVEHPFIIIGQLASITYFTILLVLFPTIAALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COLA_HORSE
Sequence: LLLVALAVAYAVPDPRGVIINLEAGEICLNSAQCKSECCHQESSLSLARCAAKASENSECSAWTLYGVYYKCPCERGLTCQVDKTLVGSIMNTNFGICFDAARSEE
What is the function of this protein?
Enterostatin has a biological activity as a satiety signal.
What are the official names of this protein?
Colipase A.
What is the protein family that this protein belongs to?
Belongs to the colipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOH_RICAH
Sequence: MTDFFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRCGPNVVGPFGLLQPIADAVKLLFKEPIIPINADKILFILAPMITFILSLIGWAVIPFSKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEVSMGFVIITVLLTTGTLNLSGIIEAQRTMPWWIDLMLLPMGIVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALFFLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTLFWVVLVSSVLFYTDNLPNV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFA_CLOBL
Sequence: MRQKLEEIKNSAINELKTTLSKDQLEAIRVKYLGKKGELTQILRGMGALSQEERPIVGKVANEVRSYIEETIKEAFSDIKNKEKSIRLENETIDITMPGKKQAVGKRHPLDLTLESMKDIFISMGFTIEEGPEVELDKYNFEALNIPKNHPARGEQDTFYINDNLVLRTQTSPIQIRTMENQKPPIKMIAPGKVYRSDSVDATHSPIFYQMEGLVVDKGITFSDLKGTLELFAKRMFGNKVKTKFRPHHFPFTEPSAEMDATCFVCNGEGCKVCKGSGWIELLGCGMVHPQVLRNCNIDPEVYSGFAFGFGVDRMVMMKYGIDDIRLLYESDMRFLNQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_NITMU
Sequence: MTFDFDVITLFPEMFNAVTRYGVTGRANENAIYRLYTWNPREFTEDNYRRVDDRPYGGGPGMVMLAEPLEKAITAARERQRACGIGSTKVVYLSPQGRPLNQNVVMELSELSALVLLAGRYEGVDERLIERQVDYEISIGDYVVSGGELASMVLMDCVVRQLPGVLGDPESANQDSFTAGLLDFPHYTRPEVYRGSVVPEVLLSGNHARIERWRLQQSLGRTWLRRPDLLALKMEKGLTAEERKLLEEFQHAYEAN
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_STRPS
Sequence: MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEIILGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEAYDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHRIKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ILEU_HUMAN
Sequence: MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP
What is the function of this protein?
Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis (PubMed:30692621).  Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection.  These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality.  Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3 (PubMed:11747453, PubMed:30692621).  Acts also as a potent intracellular inhibitor of GZMH by directly blocking its proteolytic activity (PubMed:23269243).  During inflammation, limits the activity of inflammatory caspases CASP1, CASP4 and CASP5 by suppressing their caspase-recruitment domain (CARD) oligomerization and enzymatic activation (PubMed:30692621).  When secreted, promotes the proliferation of beta-cells via its protease inhibitory function (PubMed:26701651).
What are the official names of this protein?
Leukocyte elastase inhibitor, LEI, Monocyte/neutrophil elastase inhibitor, EI, M/NEI, Peptidase inhibitor 2, PI-2, Serpin B1.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytolytic granule. Early endosome.
Protein: LIPA_CHESB
Sequence: MVTVLDTVSKPRPRHPEKAHRPDQEVLRKPDWIRVKAPTSRGYLETREIVKTNKLVTVCEEAGCPNIGECWDKKHATFMIMGEICTRACAFCNVATGIPGPLDPNEPANVAKAVREMGLNHVVITSVDRDDLNDGGAQHFADVIQAIRAATPQTTIEILTPDFLRKDGALELVVAAKPDVFNHNLETVPSKYLTVRPGARYFHSIRLLQRVKEIDPSIFTKSGIMVGLGEERNEVLQLMDDLRSADVDFITIGQYLQPTKKHHPVKKFVTPEEFKSYETIAYTKGFLMASSSPLTRSSHHAGEDFERLRAAREARLSLAKTA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYDC2_HUMAN
Sequence: MASSAELDFNLQALLEQLSQDELSKFKSLIRTISLGKELQTVPQTEVDKANGKQLVEIFTSHSCSYWAGMAAIQVFEKMNQTHLSGRADEHCVMPPP
What is the function of this protein?
May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome (PubMed:17339483, PubMed:17178784).  May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA (PubMed:17339483, PubMed:24871464).
What are the official names of this protein?
Pyrin domain-containing protein 2, Pyrin-only protein 2, cellular POP2, cPOP2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Recruited to specks formed by PYCARD within the cytoplasm.
Protein: GLCM2_CAEEL
Sequence: MSIAWSCFVLGLFALASLQVALANDCAQKTFKTGIVCVCNITYCDEIPDINLLSGQAATFTTSKSGARLHRDVVYATNSDPLTSMHFTIDSSKTYQTIQGFGSTFSDASGANLKSLPDQMADTILRQYFSDSGLNLQFGRVPIASNDFSSRVYTYDDNLEDYNMAHFSLQREDYQWKIPYMQMAQKYNHDLKFFAVPWSAPGWLKTTNSTKGYGILLGTNQDTYHKSYVTYILHFLEEYQKNGILFWGLSTQNEPTSGSDKKTKMQSMGFTAEFQRDFIKLDIGPALKSSNAGKNVKILILDDNRGNLPKWADTVLNDKDAASYVSGIAVHSYQDDESDKHLTQTHNNHPDVFIFGTEASEGSKSKDVDYGSFDRAEDYVSDILDDFNNWVTGWTERNLVLDAQGGPSWVSGFADAPVIAFPALAQFYKQPMFYAIAHFSHFLKPGAVRIDHSLNMPNPEIERSAFLNPDGSKVVVLHNKNPLAPYSLSIKDTMKSTDHYQVHLSPKTIVTLYIQN
What are the official names of this protein?
Putative glucosylceramidase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 30 family.
Protein: MSCL_SALSV
Sequence: MSFIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAFTLREAQGDIPAVVMHYGVFIQNVFDFVIVAFAIFVAIKLINRLNRKKAEEPAAPPAPSKEEVLLGEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSP_ECOK1
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLTNIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVVDKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDIDTLDKDVAHDSRSIQAAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: GCYA1_BOVIN
Sequence: MFCAKLKDLQITGDCPFSLLAPGQVPREPLGEATGSGPASTPGQPGVCPGVPDKNPPGRLPRRKTSRSRVYLHTLAESICKLIFPEFERLNLALQRTLAKHKIKENRKSLEREDFEKIVVDQAIAAGVPVEIIKESLGEELFKICYEEDEYILGVVGGTLKDFLNSFSTLLKQSSHCQEAEKKGRFEDASILCLDKDPDVLYVYYFFPKRITSLILPGIIKAAARILYETEVEVSSTPSRFHQDCREFVDQPCELYSVHIRSARPHPPPGKPVSSLVIPASLFCKTFPFHFMLDRDMSILQLGHGIRRLMSRRDVQGKPHFDEYFEILTPKISQTFSGIMTMLNMQFLVRVRRWDNSMKKSSRVMDLKGQMIYMVESSSILFLGSPCVDRLEDFTGRGLYLSDIPIHNALRDVVLIGEQARAQDGLKKRLGKLKATLEQAHQALEEEKRKTVDLLCSIFPSEVARQLWQGHAVQAKRFGNVTMLFSDIVGFTAICSQCSPLQVITMLNALYTRFDRQCGELDVYKVETIGDAYCVAGGLHKESDTHAVQIALMALKMMELSHEVVSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREELPPNFPSDIPGICHFLEAYQQGTTSKPWFQKKDVEEANANFLGKASGID
What are the official names of this protein?
Guanylate cyclase soluble subunit alpha-1, GCS-alpha-1, Soluble guanylate cyclase large subunit.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_RHOP2
Sequence: MIIAIDGPAASGKGTLGKRLAAHYGFRHLDTGVIYRAVAKALLDGGADLTDQAQAIAAAQGLDPGLFGDPALKSQTVGDAASVISAYPKVREVLVGFQRQFAAEPPGAVLDGRDIGTVICPDADVKIFVVADPGVRARRRALEAQARGEPADEAVILADILRRDERDKGRSAAPLKQAPDAVLLDNSNLDIEGGVRAAIAIVEAVRAGRRRV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_BACC7
Sequence: MSWSKVKYFFFDTPEEKEAAQYSYEKEQTDMKKQQDPPEQQDVTFPKAQTKQNVVSIETAKQSSKVVLLEPRTYSEAQGIADHLKGRRAVVINLQRMSTDQAVRIVDFLSGTVYAIGGDIQKIGPKTFMCTPENVDIVGAISELFGEEEDTNIKRW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: YAAI_ECOLC
Sequence: MKSVFTISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLALKLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: GRPE_CHRVO
Sequence: MQFRGNVMQENQNQAAEAVENEMTETASAAHTELEQTPEQRIAGLEAEIAELNDTLLRARAELENQRRRAQDEVAAAHKYAIGKFAAELVTVKDYLEMALLDQSGQIDALKMGVDMTLKQLVSAFDKAQIKDIAPKLGDKLDPHQHQAMSAEESDAEPNTVVRVMQKGYLLADRVLRPAMVVVAKAKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_RICFE
Sequence: MEIILIKPVRKLGKIGDMLKVADGFGRNYLLPQKLAIRATEPNKELIVKQKHEFEAKDKQIREEVEKINALIKDQKLVFIRQTSDDGKLFGSVTNKEIADKLSENVSYNIAHSNIILDKQIKFTGIYTVEIRLHAELNAIVTVIVARSESEAQDYLREQKTETSEDLAESA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: MUG_SERMA
Sequence: MELLAPNLRVVFCGINPGLSSAHQGYPFANGSNRFWKVIHQAGFTESQLAPEQWQQLKDNGCGITALVARPTVAASELSRDELRSGGEALQEKILRYQPRALAILGKQAFTTAFGVKNAPWGKQTLTLGETEVWVLPNPSGLNRATLEQLTASYRELFLALQ
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_BRASO
Sequence: MADFFASSFWTGFLWPLIIMIAQSVLLLVVLLIAIAYILLADRKIWAAVQIRRGPNVVGPFGLFQSFADLLKFVLKEPIIPAGANKGVFLLAPLVSCVLALAAWAVIPTNLGWAIADINVGILFIFAISSLSIYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVIITVLLCAGTLNLSAVVEAQHARGLASLIGLPQLTILNWYVWPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYGSTPYLLFMLGEYVAITTMCALATILFLGGWLPPIDVAPFNWVPGVIWFALKLFFMFFLIAMAKAIVPRYRYDQLMRLGWKVFLPLSLVMVVVVAGVLHFAGIAPK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECR_SALDC
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQDVCNICSNPRRQENGQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLASEKISELILATNPTVEGEATANYIAELCAEAGVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIIF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NDUB1_RAT
Sequence: MTLLQLVREHWVHILVPMGFAFGYYLDRKDDEKLTAFRNKSMLFQRELRPNEEVTWK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1, Complex I-MNLL, CI-MNLL, NADH-ubiquinone oxidoreductase MNLL subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB1 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: TRPB_SALPC
Sequence: MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RS2_FUSNN
Sequence: MSVVSMKQLLEAGVHFGHQAKRWNPKMAKYIFTERNGIHVIDLHKSLKKIEEAYEEMRKIAEDGGKVLFVGTKKQAQEAIKEQAERSGMYYVNSRWLGGMLTNFSTIKKRIERMKELEKLDAEGILDTDYTKKEAAEFRKELSKLSKNLSGIRDMEKVPDAIYVVDVKMEELPVKEAHLLGIPVFAMIDTNVDPDLITYPIPANDDAIRSVKLITSVIANAIVEGNQGIENVEPQSEEVNVEEGSAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: TIG_STRMU
Sequence: MSTSFENKATNRGVVTFTISQDKIKPALDQAFNKVKKDLTAPGFRKGHMPRTVFNQKFGEEALYEEALNSILPAAYEEAVAELELDVVTQPKVDVKSMEKGKDWEITAEVVTKPEVKLGDYKNLEVSVEESKEVTDAEVDEKIERERNNLAELVLKEDAAVEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGKKAGETVKVNVTFPEDYQSADLAGKDATFVTTIHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKELEATKETAYNDAVEAAAIDLAVANAEIVELPEEMIHDEVQRAMQEFMGNMQRQGISSEMYFQLTGTTEEDLRKQYEADADKRVKTNLVIEAVAKAEGFEATDEEIEKEISDLATEYKMEAEQVRSLLSPDMLKHDIAMKKAVNVITDSAKVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL25_ECO57
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNIQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.