PharMolix/UniProtQA huggingface dataset:
Protein: LAEA_FUSO4
Sequence: MVVMPPQNSVNESEGRYLQDGFWQHGRFYGSWKPGKYLFPIDSEELNRLDIFHKVFLLARDNKPFLAPIRRPSPRIMDIGTGTGIWAINVAEECLSDAQIMAVDLNQIQPALIPPGFMPKQYDIEEPSWGPLLTDCDLIHMRMLLGSIQTDLWPQVYHNVFEHLTPGIGFFEHIEVDWIPRCDDDERPANSAFVKWAELFLDGMDRFNRSVRVTPQEHRQMLEAAGFTDIRQEVIKAYVCPWSADRNEREIARWFNIGLSHSLEAMSLKPLIEKLGFEAEEVRELCERAKRETCVLRYHTYCNIHVWTARKPGPQQ
What is the function of this protein?
Methyltransferase that performs automethylation (By similarity).  No other methyl-accepting substrate has been identified yet (By similarity).  Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:23106229).  Controls the biosynthetic gene cluster for beauvericin, a depsipeptide mycotoxin that functions as a virulence determinant (PubMed:23106229).  The velvet complex regulates also chromatin structure and transcription of siderophore biosynthetic genes and is required for infection of tomato plants (PubMed:23106229).  The velvet complex also governs expression of nitrate metabolism genes (PubMed:24240057).
What are the official names of this protein?
Secondary metabolism regulator laeA, Methyltransferase laeA, Velvet complex subunit laeA.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SAR1_MAGOY
Sequence: MWIINWFYDVLSSLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTLHPTSEELAIGNVRFTTFDLGGHQQARRLWKDYFPEVNGIVFLVDAKDHDRFPEAKAELDALLSMEELAKVPFVILGNKIDHPEAISEEELRHQLGLYQTTGKGKVPLEGIRPIEVFMCSVVMRQGYGEGIRWLSQYV
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex.  These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase SAR1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYB_EURMI
Sequence: MTNIRKTHPLMKIVNGSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGLYYGSYMFMETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDTDKIPFHPYYTIKDILGALILILALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILALMPFLHTSKQRSMMFRPISQCLFWLLVADLLTLTWIGGQPVEHPFVIIGQLASILYFTLILILMPLASLMENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSRA_ACIB5
Sequence: MQQALFGGGCFWCVEAVFLQIRGVEKVTSGYAGGHTTHPTYEQVCQGDTQHAEVVLIDFDEQQVTYSQLLDVFFATHDPTTLNRQGNDIGTQYRSVIYYFNEEQKQAAEHTIQTLKDDDLDIVTELSPAPTFYPAEDYHQNYYEKNPSQGYCNFAIPPKLLKLHSKFQHLMKN
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TRMB_XENLA
Sequence: MADTQAMASDRGVAVTLPQKRYYRQRAHSNPMADHTFQYPVKPEVMDWSEYYPEFFKPLVPDCAHDDAKDLQERKEQHQVEFADVGCGYGGLLVALSPLFPNTLMLGLEIRVKVSDYVQDRIKSLRASHLGQYQNIACIRSNAMKYLPNFFKKGQLSKMFFLFPDPHFKKTKHKWRIISPTLLAEYSYALRVGGMVYTITDVEEVHEWMVKHFTEHPLFERVEKEELVSDIIVDKLGTSTEEGKKVQRNKGQNFLAVFRRIENRTFIQRDSQQ
What is the function of this protein?
Catalytic component of METTL1-WDR4 methyltransferase complex that mediates the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs).  Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in a large subset of tRNAs that contain the 5'-RAGGU-3' motif within the variable loop.  M7G46 interacts with C13-G22 in the D-loop to stabilize tRNA tertiary structure and protect tRNAs from decay.  Also acts as a methyltransferase for a subset of internal N(7)-methylguanine in mRNAs.  Internal N(7)-methylguanine methylation of mRNAs regulates translation.  Also methylates a specific subset of miRNAs.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Methyltransferase-like protein 1, mRNA (guanine-N(7)-)-methyltransferase, miRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLN1A_STAAU
Sequence: MPKRTFTKDDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMFDGSSIEGFVRIEESDMYLHPDLDTWVIFPWTAGQGKVARLICDVYKTDGTPFEGDPRANLKRVLKEMEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFDLAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKLVVKTIARKHNLHATFMPKPLFGVNGSGMHFNVSLFKGKENAFFDPNTEMGLTETAYQFTAGVLKNARGFTAVCNPLVNSYKRLVPGYEAPCYIAWSGKNRSPLIRVPSSRGLSTRIEVRSVDPAANPYMALAAILEAGLDGIKNKLKVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKAMRENEVIKKALGNHIYNQFINSKSIEWDYYRTQVSEWERDQYMKQY
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism.  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA.  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation.  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity.  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_ACIAC
Sequence: MNAPDKFAQLLALTREPFPASTKNYLIGSRPDVRVPVRDIALTNGEQVSVYDTSGPYTDPAAEIDVRRGLPSVRGAWIEGRGDTERYEGRQRVALDDGSKSEDAARLAQLRAEAAALQRAPLRAKSGASHTGNVTQMHYAKKGIVTPEMEYVALRENGRREWMAQYQQDAAREQRLAGNPMGASIPKIITPEFVRDEVARGRAIIPANINHPEVEPMAIGRTFKVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGKNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGIAEDLTWEIFRDTLVEQAEQGVDYFTIHAGVRLAFIHLTAQRRTGIVSRGGSIMAKWCMAHHRESFLYEHFEDICDIMKQYDVSFSLGDGLRPGCASDANDEAQFAELRTLGELTRTAWKHDVQTMIEGPGHVPMHMIQANMTEQLRTCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWMGTAMLCYVTPKEHLGLPDRDDVKQGIIAYKIAAHAADVAKGHPGARARDDALSQARFDFRWQDQFNLGLDPETAQQYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREFAAQGMQEKAREFRGTGGELYVPIQPA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RLME_BORAP
Sequence: MNDEYSQKAKREGYLARSVYKLIEINEKFSLFSYGNVLDIGASPGSFSQYAYKKLKRGILVAVDINDIGLRHVDNFYFVKGDIFSDDTVFKINTLGPYSLVISDAAPRTTGNRLVDTSNSFNLSMRIIDLSLEVLIKKGNLLVKVFQGGDEIQIFKKFEKYFKFVKKIRPKAVRKNSFEIYFLGKSFGK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_HERA2
Sequence: MLTPSSIADCWHSLRQQRPLVHVVPNLVTANDLANALLAVGAAPIMAIEPAEFSQLPNRALVLSMGTPTIDRMQLLAQAGRAAQAKNLPIVLDPVGVGATVWRKQAALALIATVQPTILRLNLGEALALLDQTGVAHGVDVGHAWHDPRLVAGQLARRYGCVVGLTGVIDVVSDGMNWIQLEHGHQWLSQITGAGCIVTSLIGALAAVINDVMLATVSAIAGFGMAAEVAAMHALGPASFRVALFDQLGAIAELIDNSRLSYRMEQHDAD
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: POTC_ECOLI
Sequence: MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTTKWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKIYSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK
What is the function of this protein?
Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.
What are the official names of this protein?
Spermidine/putrescine transport system permease protein PotC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAD_STRZP
Sequence: MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTEMGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLAELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDKPETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADD_METM5
Sequence: MILVKDAIINGKKQNMLVEGNIIKKIGNISNSEVSKDETEIIDGKNCVLIPGLINTHTHVPMSLFRGVADDIPLMDWLSGHIWPMESKLNEKIVYAGTLLGTIEMIKSGTTAFNDMYFFLDSIIKAVDETGIRSTIAYGMIDLFDEEKREKELKTARESLEMIKNLNNSRITGALGPHAPYTCSKEILESTNALAREFNVPIHIHMNETLDEINQVVERTGMRPFEYLNSFGFFEDVTTICAHCVHLSDSEIQIMKEKNMFAAHNPVSNLKLASGVSPVLKLLENNIPVTLGTDGCGSNNNMNLFEEIKAVALIHKGVNLNPVAVTAKEAFEFGTKNGAKALNINSGEIKEGKLADFVLINMKKPYLTPKENIESHLVYSFNGVVDTVVIDGKIVLNAGKMVNIDEEKVYELAEEAYFELAK
What is the function of this protein?
Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs.  Can also deaminate adenosine.  The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
What are the official names of this protein?
5'-deoxyadenosine deaminase, 5'-dA deaminase, 5'-methylthioadenosine deaminase, MTA deaminase, Adenosine deaminase, S-adenosylhomocysteine deaminase, SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: RL7_DEHMC
Sequence: MTIDEMMSAIKGMTVIELSELVKALEKEFGVSAAVAVAAPTAGGAAAAAAVEEKTEFNVILKDVGANKINVIKAVRELTSLGLKEAKDMVEAAPKAVKENVSKEEADAAKKALEAAGATVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: LGT_POLSJ
Sequence: MLIHPQINPVALQLGPLAIHWYGLTYLAAFGLFFFLATRRLRHEPYASITGPGAWSRKDIEDILFLGVMGVVIGGRLGYCLFYKPGYYLAHPLEILAVWQGGMSFHGGMLGVLASQFWFARTRQRPWLQVMDFVAPCVPTGLAAGRMGNFINGELWGRFSSPDLPWGMVFRNSGSMLPRHPSQVYQFLLEGLLLFVLLWLYARKPRKMGQVSGAFLVGYGVFRFIAEYFREPDDFLGILALGLSMGQWLCVPMIVGGAGLWWWASQRAASAPAARA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MZM1_PICST
Sequence: MSISNVSAAKSAYRNALRATRIAFRQDVPVLSSARLQIKDGFTKNRELKDEAEISEAISKLNEVSKFLVQNIVQGEKQEDGKYFLNFHEKTELGDNETIRQGNKANLGSLAGAKVKKCSDN
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NDF2_RAT
Sequence: MLTRLFSEPGLLSDVPKFASWGDGDDDEPRSDKGDAPPQPPPAPGSGAPGPARATKPVSLRGEEVPEPTLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGDQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDSSPDHEKSYHYSMHYSALPGSRPAGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN
What is the function of this protein?
Transcriptional regulator implicated in neuronal determination.  Mediates calcium-dependent transcription activation by binding to E box-containing promoter.  Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons.  Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression.  Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex.  Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis.  Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity).
What are the official names of this protein?
Neurogenic differentiation factor 2, NeuroD2, Brain bHLH protein KW8.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMU_AZOSB
Sequence: MEVVILAAGQGKRMRSVLPKVLQPLAGKPMLSHVLDAARTLAARRICVVYGHGGEVVRERLDAADLAWARQEPQLGTGHAVQQALPHLTDGDLALVLYGDVPLIGVPTLQRLAAAAGDTRLALLTVELDNPTGYGRILRDAAGRVVRIVEEKDASDAERRVREVNTGILVAPVARLRAWLGSLRNDNAQGEYYLTDIIGMAVAEDIEVVTVQPDAVSETLGVNSKPQLAELERIHQRNIAQRLMEDGVTLIDPARIDVRGELVCGRDVEIDVNCVFEGRVELGDGVRIGANCVVRDARIGSGTRVAPFSHIEQTVMGPACVIGPYARTRPGTELGEDVHLGNFVEVKNSVIAAHSKANHLAYVGDADVGQRVNIGAGTITCNYDGANKFRTVIEDDVFIGSDTQLVAPVRVGRGATLGAGTTLTKDAPPEQLTVSRAKQLSIAGWKRPVKQR
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANO2_HUMAN
Sequence: MATPGPRDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGESTRSSSVINNYLDANEPVSLEARLSRMHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPTKKEMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQEKDTFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPALRSPGGGDRSRSRAASSAPSGQSQLGSMMSSGSQHTNV
What is the function of this protein?
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction.  Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process.  May mediate light perception amplification in retina.
What are the official names of this protein?
Anoctamin-2, Transmembrane protein 16B.
What is the protein family that this protein belongs to?
Belongs to the anoctamin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SDHD_BACAC
Sequence: MKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIAKVFPETKDTGGIIESPLVKIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEEDDYSILDSDTCREFFATYSIAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDAYLQEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: BCAS1_HUMAN
Sequence: MGNQMSVPQRVEDQENEPEAETYQDNASALNGVPVVVSTHTVQHLEEVDLGISVKTDNVATSSPETTEISAVADANGKNLGKEAKPEAPAAKSRFFLMLSRPVPGRTGDQAADSSLGSVKLDVSSNKAPANKDPSESWTLPVAAGPGQDTDKTPGHAPAQDKVLSAARDPTLLPPETGGAGGEAPSKPKDSSFFDKFFKLDKGQEKVPGDSQQEAKRAEHQDKVDEVPGLSGQSDDVPAGKDIVDGKEKEGQELGTADCSVPGDPEGLETAKDDSQAAAIAENNNSIMSFFKTLVSPNKAETKKDPEDTGAEKSPTTSADLKSDKANFTSQETQGAGKNSKGCNPSGHTQSVTTPEPAKEGTKEKSGPTSLPLGKLFWKKSVKEDSVPTGAEENVVCESPVEIIKSKEVESALQTVDLNEGDAAPEPTEAKLKREESKPRTSLMAFLRQMSVKGDGGITHSEEINGKDSSCQTSDSTEKTITPPEPEPTGAPQKGKEGSSKDKKSAAEMNKQKSNKQEAKEPAQCTEQATVDTNSLQNGDKLQKRPEKRQQSLGGFFKGLGPKRMLDAQVQTDPVSIGPVGKSK
What is the function of this protein?
Required for myelination.
What are the official names of this protein?
Breast carcinoma-amplified sequence 1, Amplified and overexpressed in breast cancer, Novel amplified in breast cancer 1.
Protein: TRMFO_STRA3
Sequence: MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKSTPQHKTDNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREGYSEAVTEEIHKHPLIEVIRDEITDIPGDAITVIATGPLTSDSLAAKIHELNGGDGFYFYDAAAPIVDKNTIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYKGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLDQTFATRKNPNLFFAGQMTGVEGYVESAASGLVAGINAARRFNGESEVVFPQTTAIGALPHYITHTDSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIATRALKDLEKFLNY
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_LACLA
Sequence: MIKETDLENIPDLLVKFNEPLSKYTYTKVGGPADILAFPATIEALTELLVKAKSTDTAVTVLGNASNLIVRDGGIRGLVILLEKLESVKVAGYTIEAQAGAKLKEVTQVAQANSLTGFEFACGIPGSIGGAVFMNAGAYGGEISQVLVSCKVMDTDGNISVLTASEMQFGYRHSVIRDKNLVVLSAKFELQAGDPTQIQNEMNRLNFLRESKQPLEYPSCGSVFKRPVGHFAGQLIQEANLQGVRIGGVEVSKKHAGFMVNVANGNATDYEKLIAHVIDKVKENSGVTLEPEVRIIGEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.