PharMolix/UniProtQA huggingface dataset:
Protein: PHP_ECOLI
Sequence: MSFDPTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLMTRGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVACTGYYQDAFFPEHVATRSVQELAQEMVDEIEQGIDGTELKAGIIAEIGTSEGKITPLEEKVFIAAALAHNQTGRPISTHTSFSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYPDEKRIAMLHALRDRGLLNRVMLSMDITRRSHLKANGGYGYDYLLTTFIPQLRQSGFSQADVDVMLRENPSQFFQ
What is the function of this protein?
Catalyzes the hydrolysis of phosphorylated glyceryl acetates in which the presence of a phosphate group is required for the enzymatic hydrolysis.  Hydrolyzes a dibutyl glycerol derivative suggesting it acts on phosphoglycerol substrates with a butyrate leaving group.  Also active with aromatic acetates and propionates.  No activity with various sugar phosphates, with various nitrophenylphosphate or nitrophenylphosphonate derivatives, or with phosphorylated or non-phosphorylated sugar lactones tested.  Does not hydrolyze non-phosphorylated carboxyesters with long chain leaving groups (PubMed:30277746).  No general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities detected when tested with the following non-specific substrates: p-nitrophenyl acetate, L-alanine nitroanilide, p-nitrophenyl sulfate, bis(p-nitrophenyl) phosphate, paraoxon, and p-nitrophenyl phosphate (PubMed:9548740).
What are the official names of this protein?
Phosphotriesterase homology protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
Protein: RL18_BORA1
Sequence: MDKKVTRLRRAVPTRRKITQLGVHRLSVFRSNQHIYANIISPEGDRVVVSASTLEAEVRTQLAGQSGAGGNAAAAALIGKRVAEKAKAAGIELVAFDRSGFRYHGRVKALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: LDHD_STAAM
Sequence: MTKIMFFGTRDYEKEMALNWGKKNNVEVTTSKELLSSATVDQLKDYDGVTTMQFGKLENDVYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRFPDIERRVQTHDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYPNKDLDFLTYKDSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIAFFSDEAVQNLVEGGLNAALSVINTGTCETRLN
What are the official names of this protein?
D-lactate dehydrogenase, D-LDH, D-specific 2-hydroxyacid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: PIT_BACSU
Sequence: MDILLILTILIVICALAFDFINGFHDTANAIATSVSTKALKPRHAIILAAVMNFVGAMTFTGVAKTITKDIVDPYTLENGSVVILAALLAAIAWNLITWYYGIPSSSSHAIIGAIAGAAIAAAGFAALNYKGFIKIIEALILSPIIAFVLGFILYSIVKLIFKDSNLAKTNKQFRRVQIVTAALQSYTHGTNDAQKAMGIITMALITANLHTSANDIPTWVQFACATAMGLGTSIGGWKIIKTVGGKIMKIRPVNGVSADLTGAAIIFGATFIHLPVSTTHVISSSILGVGASHRVKGVNWGTAKRMLITWVITLPISATLGAIAYFILNMIF
What is the function of this protein?
Low-affinity inorganic phosphate transporter.
What are the official names of this protein?
Probable low-affinity inorganic phosphate transporter.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL14_VIBCM
Sequence: MIQMQTMLDAADNSGARSVMCIKVLGGSHRRYAHVGDIIKVTVKEAIPRGKVKKGDVLKAVVVRTRKGVRRPDGSVIRFDRNACVLLNNNSEQPIGTRIFGPVTRELRNAKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: VATB_HALOH
Sequence: MLTKEYRGVASINGPLVVVDGVTDVGFDEMVEVITPDKHKRRGRVLQVSKNRAVIQVFEGTSGLATETTRVKFLRHPMEIALSRDILGRVFNGVGEPIDGGGEVYSNKKYNINGNAINPYSRQYPRNYIQTGVSAIDGLITLIRGQKLPIFSGNGLPHNQLAAQIARQARLGDDNEDFAVVFVAMGIKHDDANFFINSFEKSGVLQNVVVFLNLADDPAVERIIAPRIGLTAAEYLAFEEGMHILVIMTDMTNYCEALRELSSRREEVPSRKGYPGYLYSDLASLYERAGMIKGERGSITQLPILTMPNDDITHPVPDLTGYITEGQIVLKRDLYQRGVYPPINILPSLSRLMKDGIGEGFTREDHPNVSSQLYAAYSRVQEVKSLASVIGEDELSSLDQTYLKFGRVFEKRFLSQGREENRTIEQTLDLAWEVLSELPPTELDRISGEELEKYYRGSVNDNG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RN128_PONAB
Sequence: MGPPLGAGVSCRGGCGSSRLLAWCFLLALSPQAPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAGDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDREIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGADEPPLEEHVQSTNENLQLVNHEANSVAVDVIPHVDNPTFEEDETPHQETAVREIKS
What is the function of this protein?
E3 ubiquitin-protein ligase that catalyzes 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains formation.  Functions as an inhibitor of cytokine gene transcription.  Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production.  Ubiquitinates ARPC5 with 'Lys-48' linkages and COR1A with 'Lys-63' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse.  Functions in the patterning of the dorsal ectoderm; sensitizes ectoderm to respond to neural-inducing signals.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF128, RING finger protein 128, RING-type E3 ubiquitin transferase RNF128.
What are the subcellular locations of this protein?
Endomembrane system; Single-pass membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note=Localized in an asymmetric perinuclear punctate manner. Localizes to the internal pool of the transferrin recycling endosomal pathway. Partially colocalized with the endoplasmic reticulum resident HSPA5, with Golgi resident STX5, and with the late endosomal GTPase RAB7A.
Protein: TKSU_THEKO
Sequence: MKKSIALVLSIVLLAALFAVPASAGEQNTIRVIVSVDKAKFNPHEVLGIGGHIVYQFKLIPAVVVDVPANAVGKLKKMPGVEKVEFDHQAVLLGKPSWLGGGSTQPAQTIPWGIERVKAPSVWSITDGSVSVIQVAVLDTGVDYDHPDLAANIAWCVSTLRGKVSTKLRDCADQNGHGTHVIGTIAALNNDIGVVGVAPGVQIYSVRVLDARGSGSYSDIAIGIEQAILGPDGVADKDGDGIIAGDPDDDAAEVISMSLGGPADDSYLYDMIIQAYNAGIVIVAASGNEGAPSPSYPAAYPEVIAVGAIDSNDNIASFSNRQPEVSAPGVDILSTYPDDSYETLMGTSMATPHVSGVVALIQAAYYQKYGKILPVGTFDDISKNTVRGILHITADDLGPTGWDADYGYGVVRAALAVQAALG
What is the function of this protein?
Has a broad substrate specificity with a slight preference to large hydrophobic amino acid residues at the P1 position.
What are the official names of this protein?
Tk-subtilisin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERG3_ORYSI
Sequence: MVQGTLEVLLVGAKGLENTDYLCNMDPYAVLKCRSQEQKSSVASGKGSDPEWNETFMFSVTHNATELIIKLMDSDSGTDDDFVGEATISLEAIYTEGSIPPTVYNVVKEEEYRGEIKVGLTFTPEDDRDRGLSEEDIGGWKQSS
What are the official names of this protein?
Elicitor-responsive protein 3, 16 kDa phloem protein, RPP16.
Protein: XEEP_FRAP2
Sequence: MSKIIDIKTSIIKIPLKRTFITAVRSTNHIDSLAVELTLDNGVKGYGVAPATTAITGDTLQGMQYIIREIFAPVILGSDLSDYKQTLELAFKKVMFNSAAKMAIDLAYHDLLAKEQDISVAKLLGAKANSIVTDVSISCGNVAETIQNIQNGVEANFTAIKVKTGADFNRDIQLLKALDNEFSKNIKFRFDANQGWNLAQTKQFIEEINKYSLNVEIIEQPVKYYDIKAMAEITKFSNIPVVADESVFDAKDAERVIDEQACNMINIKLAKTGGILEAQKIKKLADSAGISCMVGCMMESPAGILATASFALAEDITVADLDPLDWVAKDLYSDYITFNEPNIILKDNLKGFGFNL
What is the function of this protein?
Catalyzes the epimerization of dipeptides with L-Glu in the second position.  Has epimerase activity with L-Ala-L-Glu, L-Pro-L-Glu, L-Val-L-Glu, L-Thr-L-Glu and L-Met-L-Glu (in vitro).
What are the official names of this protein?
L-amino acid-D/L-Glu epimerase, L-Xxx-D/L-Glu epimerase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: MRAY_PHOV8
Sequence: MLYYLFQYLEKFDFPGAGMFGYVSFRSLMAIILSLLISAIFGEYFINLLKRKQITETQRDASIDPFNVKKVGVPTMGGIIIIVAILIPCLLLGKLHNIYMILMLITTIWLGTLGFLDDYIKVFRKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPSVVIRENVEIQRGGEIVEVVHKEQDQKSTKTTIPFFKNNNLDYADFVGFLGNNAQAVGWIIFVLVTIFVVTAVSNGANLNDGMDGMAAGNSAIIGLTLGILAYVSSHIEYAGYLNIMYIPGSEELVIFICSFIGALIGFLWYNAFPAQVFMGDTGSLTIGGIIAVFAIIIHKELLIPILCGIFLVENLSVILQVRYFKSGKKKGHLQRVFKRAPIHDHFRTTLAQLDPNCSYLFMKPNSVFHESKITVRFWIVTIVLAAITIITLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TDRD3_CHICK
Sequence: MADRARAALSESGWYLSDEGIETCINSSEKVNTNDIILVALNTDLRTIGKKFLPSDINGGKVEKLEGPCVLQIQKIRNVSAPKDNEESQAAPRMLRLQMTDGHTSCTAIEYNSMSKISLNTPPGTKIKLSGIIEVRNGFLLLDDSNTAVLGGEVEHLIEKWELQRSLAKHSRSNIGTEGGPPPFLPFGQKCASHMQVDSRELDRRKTLQMTNTAKPVTDNDEFEKQRTAAIAEVAKSKETKTFGGGGGSSRSNLTVSAGGNRNRELFQKEKITKPEGKNEGVYRELVDEKALKHITEMGFSKEAARQALMDNSNNLEAALNFLLSSNKQKPLQGPPPRGKGKGRGRIRPEDEEELGNARPSAPSTLFDFLESKMGTLTVEEPKLQFQPPHQVQPKVMNTEQNGIKENHSRHISRNDMRQPRNEKPPRFQRDIQNSRQALESGGLPRNRGPERHNSLEHWTDEKIKSDRHYPRNDRPKDLGYPIAAHQSDISFKKRDNNMQNRIGKGVSFTEFKENSAAQDATDNNNQKRGKRENQIHNSENFCDRKARTISNETFMVKSEQHFGVNNDYQNPCRTDNFNSIPNGDTEHHQKGRRVGPIKLSGPTVIPSYDDKILYYNTGPKRRSGPIKPEKIMEPSIHAEYGKTWRPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFSDYGNYEEVLLSNIRPIHADTWEDEEETYEQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN
What is the function of this protein?
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins.  In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci.  In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins (By similarity).
What are the official names of this protein?
Tudor domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules (By similarity).
Protein: RS19_METEP
Sequence: MARSLWKGPFVDGYLLKKADAARGGSRNEVVKIWSRRSTILPQFVGITFGVHNGHKHIPVYVTEEMVGHKFGEFSPTRTFPGHAADKKAKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MURQ_BACC1
Sequence: MLENLSTEHRNEKTMNLDEMSIKEILQSMNEEDRTVALAVENEIEQIEKVVQTVIKSFEEEGRLIYIGAGTSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELADEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANRVGASTASISCNKNAEISKYAKINVEVGTGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRIIVEATGVSYEVAAEYYEKAERNVKAAIVMVLLQCEYGEALQKLKEAKGFVKKAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RPOB_AMBTC
Sequence: MLRDGNEGMSTIPGFSQIQFEGFCRFVDQGLAEELHKFPKIEDTDQEIEFQLLVETYQLAEPLIKERDAVYESLTHSSELYVPAGLIWKVGRDMQEQTVFIGNIPLMNSLGTFIVNGIYRIVINQILQSPGIYYSSELDHNGISVYTGTIISDRGGRSELEIDRKARIWARVSRKQKISILVLPSAMGSNLREILDNVCYPEILLYFPNEKEKKKIGSKENAILEFYQQFSCVGGDPVFSESLCKELQKRFFQQRCELGRIGRQNMNQRLNIDIPQNNTFLLPRDVLAATDHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLALVRLENVVRGTICGAIRHKFIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKSSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGDWGSIRSPFYEISERSKEEQMVYLSPRRDEYYMVMVAAGNSLALNQDIQDEQVVPARYRQEFVTIAWEHIDLRSIYPLQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGGSAIAQHEGKVIYTDTEKILLSGNGDTISIPLLMYQRSNKNTCMHQKPQVHRDKYVKKGQVLADGAATVGGELALGKNVLVAHMPWEGYNFEDAVLISERLVYGDIYTSFHIRKYEIQTHVTSHGPEKITNEIPHLEAHLLRNLDRNGIVMLGSWVETGDVLVGKLTPQTAKESSYAPEDRLLRVILGIQVSTAKETCLKLPIGGRGRVIDVRWIQKKGASSYNPEKIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFECSLGLAGDLLDRHYRITPFDERYEQEASRKLVFPELYEASKRTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKSYMLKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQELLGTTIVGGTIPKPEGAPESFRLLVRELRSLALELKHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GBP2_YEAST
Sequence: MERELGMYGNDRSRSRSPVRRRLSDDRDRYDDYNDSSSNNGNGSRRQRRDRGSRFNDRYDQSYGGSRYHDDRNWPPRRGGRGRGGSRSFRGGRGGGRGRTLGPIVERDLERQFDATKRNFENSIFVRNLTFDCTPEDLKELFGTVGEVVEADIITSKGHHRGMGTVEFTKNESVQDAISKFDGALFMDRKLMVRQDNPPPEAAKEFSKKATREEIDNGFEVFIINLPYSMNWQSLKDMFKECGHVLRADVELDFNGFSRGFGSVIYPTEDEMIRAIDTFNGMEVEGRVLEVREGRFNKRKNNDRYNQRREDLEDTRGTEPGLAQDAAVHIDETAAKFTEGVNPGGDRNCFIYCSNLPFSTARSDLFDLFGPIGKINNAELKPQENGQPTGVAVVEYENLVDADFCIQKLNNYNYGGCSLQISYARRD
What is the function of this protein?
Binds to intron-containing transcripts and is involved in quality control for the export of spliced mRNAs from the nucleus (PubMed:14769921, PubMed:24452287).  Binds to pre-mRNAs until splicing is completed or until faulty mRNAs are degraded.  On correctly spliced mRNAs, GBP2 and HRB1 recruit MEX67 to allow nuclear export.  On faulty mRNAs, GBP2 and HRB1 associate with the TRAMP complex that guides those pre-mRNAs to the exosome for degradation (PubMed:24452287).  Binds single-stranded telomeric sequences of the type (TG[1-3])n in vitro (PubMed:7800479).  Influences the localization of RAP1 in the nuclei (PubMed:7777547).  Involved in modulating telomere length (PubMed:12519786).
What are the official names of this protein?
Serine/arginine (SR)-type shuttling mRNA binding protein GBP2, Polyadenylate-binding protein GBP2, RAP1 localization factor 6, Single-strand telomeric DNA-binding protein GBP2, G-strand-binding protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere. Cytoplasm, P-body. Cytoplasm, Stress granule. Note=Nuclear at steady state. Export is dependent on active transcription and the export of mRNAs in general. Depends on MFT1 and HPR1 for nuclear export (PubMed:14676199). Becomes predominantly cytosolic after exposure to hypoxia (PubMed:22932476).
Protein: RT26A_SCHPO
Sequence: MLNTGLRKGLALSPITHLLKRCSSVTDNVHRVNYCYNYHTVPNLSQRNLLPLFSPEALDIAWDQHQRQVVKELNDRVKGTELEDSSVFNIIFQTAALPEHAATFQFASQAYNNHFFFQSLIGKRAADAKKNSKYEANAAINKAVNENFGSKENLLSKIHELASNSFGACWLWIVIDDYNRLNLLRTFQAGSPYLWTRWQSNDPHLISSVPDYSARPRKYAHVPILNLCLWNHAYYKDYGLLNRSRYIDTWFDCIDWSVIEERLTNSLV
What are the official names of this protein?
Putative 37S ribosomal protein S26A, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS42 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RFOX2_RAT
Sequence: MAEGGQAQQQPPQLGPGAAARGMKRESEVELPVPGAGADGPEPGLSKRPRTEEAADEGMQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTSEHNLTLYGSSQPHGEQSSNSPSNQNGSLTQTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAASSFQADVSLGNEAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPATATAATAAAAAAAAYSDGYGRVYTADPYHALAPAASYGVGAVASLYRGGYSRFAPY
What is the function of this protein?
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements.  Prevents binding of U2AF2 to the 3'-splice site.  Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.  Seems to act as a coregulatory factor of ER-alpha (By similarity).
What are the official names of this protein?
RNA binding protein fox-1 homolog 2, Fox-1 homolog B, RNA-binding motif protein 9, RNA-binding protein 9.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: YORF2_TTVV9
Sequence: MTNQWEPTTLNAWGREEAWLRSVVDSHQSFCGCNDPGFHLGLLLHSAGRHLGGPGGPQPPPAPGGPGVGGEGPRRFLPLPGLPANPEEPGHQRPPCPGGPGDAGGAGGVDAETGEGEWRPEDIAELLDGLEDAEKR
What are the official names of this protein?
Uncharacterized ORF2 protein.
Protein: TBF1_YEAST
Sequence: MDSQVPNNNESLNRFNDIIQSLPARTRLTICSLCLLDNISTQLLRFLILNANSPNIIAVLTDQTAFLSSGETEIFQTLVKLFKQIRMIYHTRSPLLSVHDVAPGLWFPNSPPPLILRGHEAFIITAIRKANLLTFLLTSLNCLNYGFELLQSIFLDIFCPNTNTVGNNSLEQSGKFLKSQAILYLDLKTQAYIAGLKEFQDETNEISLEKKQELLDLIFPSNLADILVQRRTGDSGDITLLTPSEKDFVERCDRRRENLKIVQDFNSLTQSYEWAQFIRELLDYCNKNMGLIIWGRKGRGKSPLYDFDVNEFDPQVLFSTGTRTVEFMDDQNQPSSASAFLSTARPNHYSTHTPTTDVSSKNPAITQSIVDAAVAASMSNSSSGPHSSHNNSSNSNNNGSIGLRKPKAKRTWSKEEEEALVEGLKEVGPSWSKILDLYGPGGKITENLKNRTQVQLKDKARNWKLQYLKSGKPLPDYLIKVTGNLEKIYKAKKKFSQSPNSSTIMEQNLSQHPSSAASATEDTQTHQEDSHGQNSDNMPSNGLFGNSTSDNTGFDPHLEDGM
What is the function of this protein?
Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length.  Involved in the regulation of gene expression.  52 binding sites have been identified, distributed over 15 chromosomes.  A member of the general regulatory factors (GRFs) which act as genome partitioners.  Acts as a chromatin insulator which are known as STARs (Subtelomeric anti-silencing region).  STARs prevent negative or positive transcription influence by extending across chromatin to a promoter.
What are the official names of this protein?
Protein TBF1, TBF-alpha, TTAGGG repeat-binding factor 1.
Protein: ALF_MYCTO
Sequence: MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: SRS6_ARATH
Sequence: MLGLRNIILLSPPPTQITRPSLPPVNFAAVEDNNTVGEKVCRDCGNRAKKECLFERCRTCCKSRGYNCVTHVKSTWIPSSATRSSSSPSERKKKLKIDKQSSPNVSLLPTTTSRQERGFREGLPGKIEAPAVFKRTRVTAISNNEQAEIGYQATVTISGHIFKGFLHYYGVDHNKAFPCLSQK
What is the function of this protein?
Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e. g.  YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering.  Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning.  Promotes style and stigma formation, and influences vascular development during gynoecium development.  May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM) (By similarity).
What are the official names of this protein?
Protein SHI RELATED SEQUENCE 6.
What is the protein family that this protein belongs to?
Belongs to the SHI protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACPS_TREPA
Sequence: MIIGVGIDIVEIERFVSWTHNVRLLRRFFHQEEIVDFFKNHMRAQFLATRFAAKEAFGKALGTGLRNMELRNIRVCQNGWGKPRLEVYGAAQAMLAATGGTHIQVSLTHEREVASAIVIIEGEPL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM_MACFA
Sequence: MLSRAVCGTGRQLAPALGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFEKFKEKLTAASVGVQGSGWGWLGFNKERGQLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RUVC_MARN8
Sequence: MAIILGVDPGSRITGYGLIRSEGRLLEYLDSGCIRVGEKPMAERLQTIFHSLAVLIGEYRPEEFAIEQVFMARNPDSALKLGQARGAAIVSAANSGLAVHEYSARQVKQAVVGTGGADKSQVQHMVQALLGLSRKPQADAADALAIALCHAHMNQSVLRMARTGGKVRSGRVRQP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.