PharMolix/UniProtQA huggingface dataset:
Protein: RL3_BURM1
Sequence: MSLGLVGRKVGMTRIFTAEGDSIPVTVVDVSDNRVTQIKTVETDGYTAVQVAFGSRRASRVTKPLAGHLAKAGVEAGEILKEFRIDAAKAAELSNGAIVGPDLFEVGQKVDVQGVSIGKGYAGTIKRYNFGSGRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHMGDVTVTVQNLEIARIDAERKLLLVKGAIPGAKGGKVFVTPAVKTKGAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PSAC_ORYSJ
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: IPI3_ASHGO
Sequence: MDEQVIFTTAVSGTVCQVHSVGQANLRQCAASTPNSAVLMGDKLLVAQANKALINVYSVDSRSKKEALEQRLPLPEQLSCLAVVENHTGDAGVHQQLPYLLLGSTPSGKLYVWEAGSGKLLTVKAMAHYQAITKMQAIINGKYVVTAGADSRLIIWQTASLVLEEEPKPLYVLHDHTLAITDFAVSNAHNGKYLNSKLYTVSEDMTVRCYQLSSQLEQPQLLATFTFPLALTSIALDPADRCLYVGTREGAFALPLFYKLDSSGATLVNLLQPGKHQIYSIVPEQAGVEVNKQELYRMGQLLCSKMLSCHVSLIRVSMDGSMVLLATGSGNCVVVDTYSKQPVKELAPLLAPGTQTGPVSNIITRSMTVKSDSLLQDLNLADARATEAIKIPALAKTVFDKTGTHDIIYCAPTDTLSSVLPRALDLPQYLDMIAEEDSVFANTPVTRSTVKVVGELAPAKAEALPASSAEAQQSADDTDAEVARLRESLQQLTGAYKDLRALHEKLYEEHEKLLQTSK
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat IPI3/WDR18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_CLOBM
Sequence: MYEYIKGKYIDMYKDYIVIENNNIGYKIYTSGSTMAKLPSIGENIMLYTEQIVREDFIGIYGFLTKDELSMFKLLLTINGVGAKAALSLLSISNVSTLKYAIKVGDEKTITRAPGIGKKTAQRIILELKDKIEIDISEEDDEQIINKVTDDKKVLEAVAALVTLGYSEKEASKVINLCDKNNSLEQIIKEALKHLMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MSRB_SHIDS
Sequence: MANKPSAEELKKNLSDMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGVQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: MNMA_STRA5
Sequence: MTDNSNIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVTRDENGIVHMLRGADNNKDQTYFLSQLSQEQLQKTLFPLGHLQKPEVRRIAEEAGLATAKKKDSTGICFIGEKNFKDFLGQYLPAQPGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNKPWFVVGKDLSKNILYVGQGFYHDSLMSTSLTASEIHFTRDMPNEFKLECTAKFRYRQPDSKVTVYVKGNQARVVFDDLQRAITPGQAVVFYNEQECLGGGMIDQAYRDDKICQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLA_PSEFS
Sequence: MRTLMIEPLTKEAFAPFGDVIETDGSDHFMINNGSTMRFHKLATVETAKPEDNAIISIFRADALDMPLTVCMLERHPLGSQAFIPLLGNPFLIVVAPLGDAPVSGLVRAFVTNGRQGINYHRGVWHHPVLTIEKRDDFLVVDRSGTGNNCDEHFFEEDERLILAPHQ
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: CCR2_RAT
Sequence: MEDSNMLPQFIHGILSTSHSLFPRSIQELDEGATTPYDYDDGEPCHKTSVKQIGAWILPPLYSLVFIFGFVGNMLVIIILISCKKLKSMTDIYLFNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVITSVVTWVVAVFASLPGIIFTKSEQEDDQHTCGPYFPTIWKNFQTIMRNILSLILPLLVMVICYSGILHTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLFLTTFQEFLGMSNCVVDMHLDQAMQVTETLGMTHCCVNPIIYAFVGEKFRRYLSIFFRKHIAKNLCKQCPVFYRETADRVSSTFTPSTGEQEVSVGL
What is the function of this protein?
Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (By similarity).  Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity).  Also acts as a receptor for the beta-defensin DEFB106A/DEFB106B (By similarity).  Regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiation of T-cells into T-helper 17 cells (Th17) during inflammation (By similarity).  Facilitates the export of mature thymocytes by enhancing directional movement of thymocytes to sphingosine-1-phosphate stimulation and up-regulation of S1P1R expression; signals through the JAK-STAT pathway to regulate FOXO1 activity leading to an increased expression of S1P1R (By similarity).  Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity).  Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity).  Mediates the recruitment of macrophages and monocytes to the injury site following brain injury (By similarity).
What are the official names of this protein?
C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=The chemoattractant receptors are distributed throughout the cell surface; after stimulation with a ligand, such as CCL2, they are rapidly recruited into microdomain clusters at the cell membrane.
Protein: PAND_SHIBS
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIT_METVS
Sequence: MIKDSEFYRLDGVPITKEEIRAISVEKLNICPEDIILDIGCGSGGMTVEISKRCKFVYAVDGSKDAIDTTLKNMDKFNVKNCEVYFGDAKDLISNFKVNKAFIGGTQNIESVIEKLNEKNVRNIVINTIVLENSVKVIQILERLNFSIEVISVLISYGKRISSGHMMLSKNPITIITAKK
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
Protein: GAL1_ENT38
Sequence: MSLKDKTQSLFAETFGYPATHAIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAKRDDRIVRVIAADYDNQTDEFSLDEPIVAHDTQQWSNYVRGVVKHLQMRNKGFGGADLVIAGNVPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKEHALLIDCRSLGTKAVPLPKGAAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVSLNEFNKVAHELDPVVTKRVRHVLTENARTVEAASALAQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKATIGDKGGVRMTGGGFGGCVVALIPEEWVPAVQDAVSQQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRPX2_HUMAN
Sequence: MASQLTQRGALFLLFFLTPAVTPTWYAGSGYYPDESYNEVYAEEVPQAPALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEPVTPEEIFTFIDDYLLSNQELTQRREQRDICE
What is the function of this protein?
Acts as a ligand for the urokinase plasminogen activator surface receptor.  Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords).  Involved in cellular migration and adhesion.  Increases the phosphorylation levels of FAK.  Interacts with and increases the mitogenic activity of HGF.  Promotes synapse formation.  May have a role in the perisylvian region, critical for language and cognitive development.
What are the official names of this protein?
Sushi repeat-containing protein SRPX2, Sushi-repeat protein upregulated in leukemia.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cell surface. Synapse.
Protein: PETD_WHEAT
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPTGLLTVPFLENVNKFQNPFRRPVATTVFLIGTVVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RIMO_STRGG
Sequence: MPERRTVALVTLGCARNEVDSEELAGRLAADGWDLVEDASDADVAVVNTCGFVEAAKKDSVDALLEANDLKDHGRTQAVVAVGCMAERYGKDLAEALPEADGVLGFDDYADISDRLQTILNGGIHASHTPRDRRKLLPISPAERQDTAVALPGHAQEAPAPAPEDLPEGVAPVSGPRAPLRRRLGTSPVASVKLASGCDRRCSFCAIPSFRGSFISRRPSDVLQETRWLAEQGVKEVMLVSENNTSYGKDLGDIRLLETLLPELADVDGIERIRVSYLQPAEMRPGLIDVLTSTPKVAPYFDLSFQHSAPGVLRAMRRFGDTDRFLELLDTIRSKAPQAGARSNFIVGFPGETEADLAELERFLTGARLDAIGVFGYSDEEGTEAVGYENKLDADTIAERLAHISQLAEELTSQRAEERVGETLQVLVESVESEEDGEVAIGRAAHQAPETDGQVVFTTREGLVPGLMVEAKAVGTEGVDLVAEHHELAEVAR
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_STRPD
Sequence: MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNERLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKLGKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKDYKTCLQEFLQAKGDVVIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQDAAKNALAQLSEV
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_PYRAB
Sequence: MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEGERVETAVVDDIVILFF
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_BRUSU
Sequence: MRTYLDLLQHVLDHGVDRDDRTGTGTRSVFGYQMRFDLEEGFPVLTTKKLHLRSIIHELLWFLKGDTNIAYLKENGVTIWDEWADENGDLGPVYGYQWRSWPAPDGRHIDQIANLLKMLHTNPQSRRLIVSAWNPALVDEMALPPCHCLFQFYVANGRLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLKPGEFIHTLGDAHIYSNHFEQARLQLTRTPKKLPVMHINPDVKDLFAFRFEDFRLDGYEADPTIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_HAEI8
Sequence: MIGRLQGILLEKQPPEILLNVQGVGYELLLPMTSFYDLPEIGQETTLFTHLVVREDAHLLFGFAQKTDRTLFRELIKTNGVGPKLALAILSAMSVEQFAYAIEREELSKLTKIPGVGKKTAERLLVELKGKFKGIKQSDFFVESTHIPLSPSIESHSESSSDEAISALIALGYKPAEAEKMVKRVAKPELTSEQVIREALKAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: LGT_CLOK5
Sequence: MDPIAFSIGGFQIRWYGIMIALGVLAALILANLNCRYKGYNFDSLIDVFLISFPLAIIGARVYYVVFQFQDYRNNLMDIFNIRLGGLAIHGGIIFGLGAAYIVSRYKKMDFIKLWDCFAPSIILGQAIGRWGNFFNGEAHGGIVGYEFISKFPLFIQRGMYINGDYYNPTFLYESLWDLIVCIILVYIFRKKHKRGTVICTYVGLYSLGRFFIEGLRTDSLMIGHIRVAQLVSFIGIVLSISFFVYLKGRGKRVD
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFB_LACPL
Sequence: MRISTTWLRDYLKLDIPADELAEKIERTAVEVDGVIRPSEGLKKVVVGHVLTCEPHPDSDHLHVCQVDVGESEPLQIVCGAPNVAAGEKVIVALPNSWIGGHTKIKKSKMRGVPSNGMLCALDELGFDEKLVPKEVADGIFILPDDATPGDPVFSYLGMDDEIIDMSVTPNRGDMLSMNGTAHELAAIYDQQPTMPKVDLYEDATTVAADDLHVAVAADEHDVPMYKMRLIKNVTIKPSPLWLQIRIWNAGMRPINNVVDATNYILMQYGQPLHAFDFDQLNDGQINVRLAKAGEHLTTLDGEDRELLTSDLLICSGDQPICLAGTMGGLATEVTDQTTTIALEGAVFDAVKIRKTAHNHDLHSEASMRYERGIDHGMTATALDAAAAMIAELGDGQVASGMVIGRDEDVQPTTVTIDLARINHVLGTELSLDTVSDIFKRLDFPTVVANETFTVTVPSRRWDIHIPADLIEEIARLYGYDNLPATLPTGQPTIGKLNETQQVIRDSRKLMESAGLTQAISYSLTTETKSKAFALHASDVTKLDFPMSSERTTLRLSLVSGLLDDLAYNNARKEHNVALYEEGRVFYSQPEQVRPKEIEHIAGAITGSMVPKSWGVAEQPVDFFQIKGIVAGYLKSLALQDAVSYVATAEHPEMHPGRTADIYVGDQLVGFVGEVHPTTAKAYKIRETYVFELDLTALIALPKARQQYQPISKFPSITRDVAMLIDDDVTNATVVALINKKGGAHLRHVQLFDVYNGSHVPAGKKSLAYTLTYQDQNATLVDDDVTTAFEKVLTALTDELGAEIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C7A21_PAPSO
Sequence: MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAALNSGMVKPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPSHKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFMPERFLQKHDKAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPLEARIVPRL
What is the function of this protein?
Cytochrome P450 involved in the biosynthesis of the benzylisoquinoline alkaloid noscapine (PubMed:24316226, PubMed:27378283, PubMed:29610307).  Converts (S)-tetrahydrocolumbamine to (S)-canadine (PubMed:24316226, PubMed:27378283).
What are the official names of this protein?
(S)-canadine synthase CYP719A21, Cytochrome P450 719A21.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CDK10_RAT
Sequence: MSQCQIWVRHHLCCSFQIPTLAASLFQLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCILLQVLRGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPAATEGQSKRCRP
What is the function of this protein?
Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells).  Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2.  Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling.
What are the official names of this protein?
Cyclin-dependent kinase 10, Cell division protein kinase 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: CARB_STRA5
Sequence: MPKRTDIRKIMVIGSGPIVIGQAAEFDYSGTQACLSLKEEGYQVVLVNSNPATIMTDKDIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMALSKNGILEELNVELLGTKLSAIDKAEDRDLFKQLMEELNQPIPESEIVNSVEEAIQFAEQIGYPLIVRPAFTLGGTGGGMCDNQEQLVDITTKGLKLSPVTQCLIERSIAGFKEIEYEVMRDAADNALVVCNMENFDPVGIHTGDSIVFAPAQTLSDVENQLLRDASLDIIRALKIEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPITKTTYAMFEPALDYVVAKMPRFPFDKFESGDRKLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVDHIKIADLDNVSDDVLLEKIRKAEDDRLFYLAEALRRHYSIEKLASLTSIDSFFLDKLRVIVELEDLLSKNRLDINILKKVKNKGFSDKAIASLWQINEDQVRNMRKEAGILPVYKMVDTCASEFDSATPYFYSTYAVENESLISDKASILVLGSGPIRIGQGVEFDYATVHSVKAIRESGFEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIDLEKPEGVILQFGGQTAINLAKDLNKAGVKILGTQLEDLDRAENRKQFEATLQALNIPQPPGFTATTEEEAVNAAQKIGYPVLVRPSYVLGGRAMKIVENEEDLRHYMTTAVKASPDHPVLIDAYLIGKECEVDAISDGQNILIPGIMEHIERSGVHSGDSMAVYPPQTLSETIIETIVDYTKRLAIGLNCIGMMNIQFVIKDQKVYVIEVNPRASRTLPFLSKVTHIPMAQVATKVILGDKLCNFTYGYDLYPASDMVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDINLQKALYKAFEAAYLHMPDYGNIVFTVDDTDKEEALELAKVYQSIGYRIYATQGTAIYFDANGLETVLVGKLGENDRNHIPDLIKNGKIQAVINTVGQNNIDNHDALIIRRSAIEQGVPLFTSLDTAHAMFKVLESRAFTLKVLD
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: HIS5_BURM1
Sequence: MKTSIAIVDYGMGNLRSVAQALKKAEPAADVAIVDTPAAIRAADRVVLPGQGAMPDCMRCLGESGLQEAVVEASRTKPLLGVCVGEQMLFDWSAEGDTKGLGLLPGKVVRFELDGRLQDDGSRFKVPQMGWNRVRQSRAHALWDGVPDDAYFYFVHSYYVMPDDPAHTVGETAYGAPFTSAVARDNIFATQFHPEKSAEVGLRLYRNFVHWKP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.