PharMolix/UniProtQA huggingface dataset:
Protein: TRPD_METBF
Sequence: MQRYIQRLEEGHDLSPEEAEDAVGKILSTAQDEEIGRFLLALRAKGEKPEEIAGFVRGMKKAGKTIRPKTSFRLVDTCGTGGDGLNTINISTAAAIVTAAAGVPVAKHGNRAATSMSGSSDVLDALGIKTDLEPEAVRQTIEEIGIGFMFAPVFHPAMKRVAGVRKKLGVRTVFNILGPLTNPAGTKGQVIGVFDKKLCEPIAYALAELGTEHALVVHGDGMDEITNTGETYVAELKDGKVSTYTLTPEALGMLRANPEDIKGGTPKENARDLLCIFKGQKGPKRDIVVMNAAAALYVGGIVGSIRQAIPIAEDAIDSGKVMVKFNQFKTFTSEFYRQKNKESLSGKSMSMRSRTSILSPASGERV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YBEY_WOLPM
Sequence: MLEVNILDKKWCSIIENPKNFVLGVINASLKELKIDHYKPNISIALADDDLLHQLNLKFREMDKPTNVLSFPYEQLSNECDLGDIAISIDTIKRESHEYYIPILAHIAHMLVHGLLHLLGYDHQKKDEEIIMKNLEREILASLGYNMCAI
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_VIBVY
Sequence: MNNARPIRRALISVSDKTGIVEFAQALAERGVDILSTGGTARLLAEQGIAVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDEVMAKHGINPIDMVVVNLYPFAETVAKEGCTLADAVENIDIGGPTMVRSAAKNHKDVTIVVNASDYHRVITEMDANDTSLTLETRFDLAIAAFEHTAAYDGMIANYFGTMVPSYGENKEGDEESKFPRTFNQQFIKKQDMRYGENSHQAAAFYVEANPQEASVATARQIQGKALSYNNIADTDAALECVKEFNEPACVIVKHANPCGVALGKDILEAYNRAYQTDPTSAFGGIIAFNQELDAETATAIVERQFVEVIIAPSVSAEAMEVVAAKKNVRLLECGEWTTKTTGFDVKRVNGGLLVQDRDQGMVSLDDLKVVSKRQPTEEELKDALFCWKVAKYVKSNAIVYSKGDMTIGVGAGQMSRVYSAKIAGIKAADEGLQVEGCVMASDAFFPFRDGIDAAAEAGIKCVIQPGGSMRDDEVIAAADEHGMAMIFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PRLA_ACHLY
Sequence: ANIVGGIEYSINNASICSVGFSVTR
What are the official names of this protein?
Alpha-lytic protease, Alpha-lytic endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: SYL_STRS7
Sequence: MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQAQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACAIAKMVVWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNDKQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALDKAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDKLYVAYAKGFVQLLAPFAPHLGEELWQSLTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREELEKVALAHDKIQAEIAGKEVIKVIAVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_SACEN
Sequence: MAKPDKVDAVTEIAERFNTSTAAVVTEYRGLSMAKLVQLRRALGEGTTYRVAKNTLVKRAAEQSGVEGLDELFVGPTAIAFIEGEPVDAAKALKEFAKDNKALVIKGGYMDGRPISVSEVESIADLDSREVTLGKLAGAMKAKMNQAAALFAAPATKAARLAAALQEKREGGESDAS
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL24_ANADE
Sequence: MAEIRKGDTVKVIAGKEKGKTGRVLEVLREDGRVRVEKLMTVKRHQKKGRSQANPEGGILELPGTIAISSVMVVGKDDKPVRREKIGRELGAKEKARLQKRKAAAK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: LGT_BRUSI
Sequence: MIETLLPASALAFPAIDPVIFRVGPLAVHWYGLGYVVGILFAWWYGKKLLRSHRLWANNQPPMAPEALDDFVIWAALGVVLGGRIGYVLFYNFSYYISNPLAIPALWDGGMSFHGGILGTTLAMILFARSRGILVWSMFDTIAAGVPIGLGVVRVANFINSELWGRVSDVPWAVYFPNGGPLPRHPSQLYEAFLEGLVLFFVLFVLVWGARKLKQPGFVAGAFVTGYGLSRIAVEFFREPDAQIGYLFGGWLTMGMVLSVPMVLLGLWAMWRANRAAARNA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECA2_LISIN
Sequence: MRQNYDDRKIVKQYREIARQIVRKEGLYKNMDQDELREQTNFWREKFKTKPMTERDKINIFALAREAASRIIGLDAVVVQLIGALVLGDGKVAEMKTGEGKTLMSLFVMFIEVMRGNRVHLVTANEYLARRDREEIGQVLEYLGISVALNESGLDKDQKKAIYTADVIYGTASEFGFDYLRDNMVRQKEDKVQSGLDFVLIDEADSILIDEARTPLLISDRKEEDLSLYQTANELVQTMMKDDYEIEEHKRFVWLNDAGIERAQKFWGVESLYSAEAQVELRITMLLMRAHFLMHKDKDYVVLDGEVLIIDPHTGRALPGRRFNDGLHQAIEAKEGVEVKEESRTLATITIQNYFRMYKRLSGMTGTAKTEEEEFRQIYNMDVVVIPTNLRVNREDMPDDIFYTKKEKGRAIVYEVSWRYEKGQPTLIGTSSIKSNEWISSLLDAAGIPHQVLNAKNHAQEAEIIAKAGKRGMVTLATNMAGRGTDIKLDPDVHKLGGLAVIGTERHESRRIDLQLMGRSGRRGDPGFSKFMISLEDDLLEQFESKSWEKLSTKLKRKAPRDGKPVNSRKIHSVIVDAQKRLEGANYDIRKDLLSYDEVIDLQRKMVYKERDQLLERNKLGVSSEKILREVAEYSFIHPLELEEEELEKYYSRQKELLGGTKFPISFDQVTLMDPVEVVEEIVAWHKKERNKFPVETITAIEKEVYLNLMDQMWVMHLDAMVQLREGIHLRAYGQQDPLVMYQKEGAQLFEKFQADYHFYFAHALLELDPDGLIQG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: Y132_PYRHO
Sequence: MIEFRDVWFWYQEGKTVLKSISFSFSEGTLAIVGPNGSGKTTLVKMLNGLLKPKKGNVLIDGINTKEVSVAELSRIVGYVFQNPDAMFFEENVFKEVAFGPKNLGLNEEEVKKRVRWALEAVGLRGFENRNPFELSGGEKQRLAIACILAMKPKYLVLDEPNTGLDERGLQDLINVIKNLRREGSSIILVTHDIELVLEVADKVLLLKDGELKFFGSTKEFFELDLEGFGLKEPELVKISKDVGINFVRNVEELLKVIGL
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein PH0132.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1013_MYCTU
Sequence: MSRFTEKMFHNARTATTGMVTGEPHMPVRHTWGEVHERARCIAGGLAAAGVGLGDVVGVLAGFPVEIAPTAQALWMRGASLTMLHQPTPRTDLAVWAEDTMTVIGMIEAKAVIVSEPFLVAIPILEQKGMQVLTVADLLASDPIGPIEVGEDDLALMQLTSGSTGSPKAVQITHRNIYSNAEAMFVGAQYDVDKDVMVSWLPCFHDMGMVGFLTIPMFFGAELVKVTPMDFLRDTLLWAKLIDKYQGTMTAAPNFAYALLAKRLRRQAKPGDFDLSTLRFALSGAEPVEPADVEDLLDAGKPFGLRPSAILPAYGMAETTLAVSFSECNAGLVVDEVDADLLAALRRAVPATKGNTRRLATLGPLLQDLEARIIDEQGDVMPARGVGVIELRGESLTPGYLTMGGFIPAQDEHGWYDTGDLGYLTEEGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLDAGHSRESFAVAVESNAFEDPAEVRRIEHQVAHEVVAEVDVRPRNVVVLGPGTIPKTPSGKLRRANSVTLVT
What are the official names of this protein?
Putative ligase Rv1013.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: YJD3_SCHPO
Sequence: MWVTCHLLKREKDEMKKKWREWAKEVCQFGKRILCISITDAALVNLEVLEPKNFEPGTLDGAGLFGCWSANGLGIALAYEITNSRFEINSGYTVKVKCLKRFQGEARG
What are the official names of this protein?
Uncharacterized protein C594.03.
Protein: TRPA1_HUMAN
Sequence: MKRSLRKMWRPGEKKEPQGVVYEDVPDDTEDFKESLKVVFEGSAYGLQNFNKQKKLKRCDDMDTFFLHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTIIRSKRWDECLKIFSHNSPGNKCPITEMIEYLPECMKVLLDFCMLHSTEDKSCRDYYIEYNFKYLQCPLEFTKKTPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEYLLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTGIINETSDHSEILDTTNSYLIKTCMILVFLSSIFGYCKEAGQIFQQKRNYFMDISNVLEWIIYTTGIIFVLPLFVEIPAHLQWQCGAIAVYFYWMNFLLYLQRFENCGIFIVMLEVILKTLLRSTVVFIFLLLAFGLSFYILLNLQDPFSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGMLFHIFCFLFCTGEIRQEIPNADKSLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISETEDDDSHCSFQDRFKKEQMEQRNSRWNTVLRAVKAKTHHLEP
What is the function of this protein?
Receptor-activated non-selective cation channel involved in pain detection and possibly also in cold perception, oxygen concentration perception, cough, itch, and inner ear function (PubMed:21873995, PubMed:23199233, PubMed:25389312, PubMed:25855297).  Shows 8-fold preference for divalent over monovalent cations (PubMed:31447178).  Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of irritants, such as allylthiocyanate (AITC) from mustard oil or wasabi, cinnamaldehyde, diallyl disulfide (DADS) from garlic, and acrolein, an irritant from tears gas and vehicle exhaust fumes (PubMed:25389312, PubMed:27241698, PubMed:30878828, PubMed:20547126).  Acts also as an ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana (PubMed:25389312).  Is activated by a large variety of structurally unrelated electrophilic and non-electrophilic chemical compounds.  Electrophilic ligands activate TRPA1 by interacting with critical N-terminal Cys residues in a covalent manner, whereas mechanisms of non-electrophilic ligands are not well determined.  May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds.  Probably operated by a phosphatidylinositol second messenger system (By similarity).
What are the official names of this protein?
Transient receptor potential cation channel subfamily A member 1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, p120, Wasabi receptor.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZHANG_MOUSE
Sequence: MRHSLTKLLAASGRDFPSRRDSREPPATRAPPREPSGAAAGAETPRPGSPDREQPHGDGDGGEPEARSGSRGSVAVRAPAPSPLKMEEEEEDAIAMVPKEEPEDMDFLSGLELADLLDPRQPDWHLEPGLSSPGPLSSSGGGSESGGLLRGDDDDDTAAAEMQRFSDLLQRLLNGIGGCSSGGDRGGGEKRRRKSPGAGGGGANDGNQAATKSPRKAAAAAARLNRLKKKEYVMGLESRVRGLAAENQELRAENRELGKRVQALQEESRYLRAVLANETGLARLLSRLSGVGLRLTTSLFRDSPAGDHDYALPVGKQPPEPREEDDAAGGVCLHVDKDKVSVEFCSACARKASSSLKM
What is the function of this protein?
Strongly activates transcription when bound to HCFC1.  Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner.  Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell.  Able to down-regulate expression of some cellular genes in CREBZF-expressing cells (By similarity).
What are the official names of this protein?
CREB/ATF bZIP transcription factor, Host cell factor-binding transcription factor Zhangfei, HCF-binding transcription factor Zhangfei, Tyrosine kinase-associated leucine zipper protein LAZip.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes in promyelocytic leukemia protein nuclear bodies (PML- NB) with CREB3 and HCFC1.
Protein: CP17A_ONCMY
Sequence: MAWFLCMCVFSVVGLGLLLLQVKLRRSLETRGGPPSLPVFPLIGSLLSLRSNQAPHVLFQKLQQKYGHTYSLMMGPHTVILVNHHQHAKEVLLKKGKIFAGRPRTVTTDLLTRDGKDIAFADYGATWRFHRKTVHGALCMFGEGSASIEKIICREALSLCDTLRESGSASLDLSPELTRAVTNVVCSLCFSSSYCRGDPEFEAMLQFSQGIVDTVAKDSLVDIFPWLQVFPNADLRLLKQCVSIRDKLLQKKYEEHKSDYSDHEQRDLLDALLRAKRSAENNNTAEITMETVGLSEDHLLMTVGDIFGAGVETTSTVLKWAIAYLIHHPQVQQRIQEELDSVVGGDRTPQLSDRGSLPYLEATIREVLRIRPVAPLLIPHVAQTDTSIGKFTVRKGARIIINLWSLHHDEKEWKNPEMFDPGRFLNEEGTGLCIPSPSYLPFGAGVRVCLGEALAKMEIFLFLSWILQRLTMTVSPGQPLPSLEGKFGVVLQPVKYKVNATPRAGWEKSHLQTS
What is the function of this protein?
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione.  Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: RS4_BACCR
Sequence: MARYTGPAWKLSRRLGISLSGTGKELEKRPYAPGPHGPNQRKKLSEYGLQLQEKQKLRHMYGMTERQFRRTFDQAGKMPGKHGENFMILLEARLDNLVYRMGLARTRRAARQLVNHGHIMVDGARVDIPSYRVKPGQTISVREKSNSLVVVKEAIEVNNFVPEYLTFDADKLEATYTRHAERSELPAEINEALIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CALCR_MOUSE
Sequence: MTPRRSRVKRRNLRKPKMRFLLVNRFTLLLLLLVSPTPVLQAPTNLTDSGLDQEPFLYLVGRKKLLDAQYKCYDRIHQLPSYEGEGLYCNRTWDGWMCWDDTPAGATAYQHCPDYFPDFDTAEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTSEKLQNAYVLYYLALVGHSLSIAALVASMLIFWIFKNLSCQRVTLHKHMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTHMWTMQWELSPPLPLSAHEGKMDPHASEVISCKVLHFLHQYMMSCNYFWMLCEGIYLHTLIVMAVFTDEQRLRWYYLLGWGFPIVPTIIHAITRALYYNDNCWLSAETHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRQTHEAESYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQVTLKRQWTQFKIQWSQRWGRRRRPTNRVVSAPRAVAFAEPDGLPIYICHQEPRNPPISNNEGEESTEMIPMNVIQQDASA
What is the function of this protein?
This is a receptor for calcitonin.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.
What are the official names of this protein?
Calcitonin receptor, CT-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VM3B1_BOTJR
Sequence: EFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGRQITTYPPVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTETNWEYEEPIKKASKLVVTAEQQKFPYRYVEIVVVVDRRMVTKYNGDLKKIRKWVYELVNIVNNIYRSLNVHVALVGLEIWSKGDKITVQPDSDYTLNSFGEWRERDLLPRKKHDNAQLLTAVVFDGPTIGRAYIAGMCDPRHSVGVVMDHSKENLQVAVTMAHELGHNLGMEHDENQCHCDAPSCVMASVLSVVLSYEFSDCSQNQYQTYLTKHNPQCILNEPLLTVSGNELLEAGEECDCGAPENPCCDAATCKLRPGAQCAEGLCCDQCRFKGAGKICRRARGDNPDDRCTGQSADCPRNRFHRNGQPCLYNHGYCYNGKCPIMFYQCYFLFGSNATVAEDDCFNNNKKGDKYFYCRKENEKYIPCAQEDVKCGRLFCDNKKYPCHYNYSEDLDFGMVDHGTKCADGKVCSNRQCVDVNEAYKSTTVFSLI
What is the function of this protein?
This protein is a zinc metalloprotease from snake venom that causes hemorrhage in mice after intradermal injection.  It inhibits platelet aggregation induced by collagen and ADP.  Has moderate edema activity, but no myotoxic activity.  It hydrolyzes the Aalpha-chain and more slowly the Bbeta-chain of fibrinogen, without affecting the gamma-chains.  It also shows proteolytic activity on casein.  It is unable to clot plasma.  It also shows bactericidal activity against E. coli and S. aureus.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like BjussuMP-1, BjussuMP-I, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DCK_MOUSE
Sequence: MATPPKRFCPSPSTSSEGTRIKKISIEGNIAAGKSTFVNILKQASEDWEVVPEPVARWCNVQSTQEEFEELTTSQKSGGNVLQMMYEKPERWSFTFQSYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESDCMNETEWTIYQDWHDWMNSQFGQSLELDGIIYLRATPEKCLNRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTSFDYLQEVPVLTLDVNEDFKDKHESLVEKVKEFLSTL
What is the function of this protein?
Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine.
What are the official names of this protein?
Deoxycytidine kinase, dCK, Deoxyadenosine kinase, Deoxyguanosine kinase.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDTL_SALTY
Sequence: MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGKIADQSGRKPVAIVGALVFMMASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVVGHLIMLRFPWQSLFYTMSAMGIIVGLLSLFILRETRPVRLAPRDLSRSSPAAESLINRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRGDYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVTPNRSVAEHEEIPYQSRP
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACP_PECCP
Sequence: MSTIEERVKKIIVEQLGVKQEEVVNNASFVDDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDFIQANQQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBL_MYCBO
Sequence: MIPNPLEELTLEQLRSQRTSMKWRAHPADVLPLWVAEMDVKLPPTVADALRRAIDDGDTGYPYGTEYAEAVREFACQRWQWHDLEVSRTAIVPDVMLGIVEVLRLITDRGDPVIVNSPVYAPFYAFVSHDGRRVIPAPLRGDGRIDLDALQEAFSSARASSGSSGNVAYLLCNPHNPTGSVHTADELRGIAERAQRFGVRVVSDEIHAPLIPSGARFTPYLSVPGAENAFALMSASKAWNLGGLKAALAIAGREAAADLARMPEEVGHGPSHLGVIAHTAAFRTGGNWLDALLRGLDHNRTLLGALVDEHLPGVQYRWPQGTYLAWLDCRELGFDDAASDEMTEGLAVVSDLSGPARWFLDHARVALSSGHVFGIGGAGHVRINFATSRAILIEAVSRMSRSLLERR
What are the official names of this protein?
Putative cystathionine beta-lyase, CBL, Beta-cystathionase, Cysteine lyase, Cysteine-S-conjugate beta-lyase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily.
Protein: RL13_STAAB
Sequence: MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GLK_SALPC
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVVRVYLDEHSVSVEDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGGEPVDGKPIAVYGAGTGLGVAHLVHVDKRWISLPGEGGHVDFAPNSEEEAMILEILRAEIGHVSAERVLSGPGLVNLYRAIVKSDNRLPENLRPKDITERALADNCIDCRRALSLFCVIMGRFGGDLALTMGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKDYVHGIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DODA_BETVU
Sequence: MGSEDNIKETFFISHGTPMMAIDDSKPSKKFLESWREKIFSKKPKAILVISAHWETDQPSVNVVDINDTIYDFRGFPARLYQFKYSAPGSPELANRIQDLLAGSGFKSVNTDKKRGLDHGAWVPLMLMYPEADIPVCQLSVQSHLDGTHHYKLGQALAPLKDEGVLIIGSGSATHPSNGTPPCSDGVAPWAAAFDSWLETALTNGSYEEVNKYETKAPNWKLAHPWPEHFYPLHVAMGAAGENSKAELIHNSWDGGIMSYGSYKFTST
What is the function of this protein?
Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid.  Produces mainly (S)-betalamic acid.
What are the official names of this protein?
4,5-DOPA dioxygenase extradiol.
What is the protein family that this protein belongs to?
Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_MANSM
Sequence: MTTQNFLAEIGTEELPPKALKKLATAFAENVENELNQAGLTFEKVQWFAAPRRLAVKVLNLATSQPTKEIEKRGPAVSAAFDAEGKPTKAAEGWARGCGITVEQAERLATDKGEWLVHRATIEGQPTKNLMLDIVTRSLANLPIPKMMRWGDKTEQFVRPVHTVSLLLGGELIEGEILGIASGRTIRGHRFLGEAEFQIAHADEYPQILKDKGSVIADFNERRAIILADSQAKASALGGVADIEDDLLDEVTSLVEFPNVLTATFEERFLAVPAEALVYTMKGDQKYFPIYDKNGKLLPHFIFVSNINPTDPTPIIEGNEKVVRPRLSDAEFFFNTDKKQRLEDLLPRLETVLFQQQLGTLLDKTKRIQALAGEIATQIGADKAKAERAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEDEEVAVALNEQYMPRFAGDNLPNSLVASSVALADKFDTLTGIFGIGQAPKGSADPFALRRAALGALRIIVEKNLPLDLAEIVKKSTALFADRLTNQNVVDDVVDFMLGRFRAWYQDEGIAVDVIQAVLARRPTKPADFDARVRAVSHFRTLDSAEALAAANKRVSNILAKIEGEISSKIDRTLLLEPEEKALAEQVLALQSELAPLFAKGEYQPALDRLAGLREVIDNFFDKVMVNAEDEKLRQNRQAILNTLRNLFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_DICNV
Sequence: MKNEIQDGLGSALILVAKNHGIDIRLLDQAIEIERCKDPENGDFASNIALKYAKVFKMKPRQLADELVVSVPLMDSVAGMEVAGPGFINIRLSRESITAVLENVVAKKERYGCFENPNARKILVEFVSANPTGPLHVGHGRGAAYGDSLSRLLIANGHQVDREYYINDFGRQMDILALSVYWRYVQECGIGVALPKGIYQGDYVIDIAKKLKEKEGKRLAYPVNEWAPDYPQTWTQEQVDNGDRDRWIDGAIAGLKEKLGQKEYRGVFDLALSMELDDIRGDLEEFGVFFDRWFSERSMSENDMINNALKKVDEAGYLYEKDGAVWFKSTAFGDEKDRVVRRKNGMTTYFSSDISYHFDKYNRGYDQMIDILGADHHGYMARVRASLAALGLDPEKLVIALVQFAVLYKGGEKMQMSTRSGEFVTLRDLREHVGADAARFFYVMRKPEQHLDFDLDLAESNSKDNPFYYVEYAHARCCGMLNKAEEEGYEFSPEAALKCRNALVEPEETALISELHRYPEVVIAAGKQMAPHQVIIYLKELATRWHHYYDVGHKVLHEDEEIRNARLLLTWAVRQVLRNALAIIGVQARERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.