PharMolix/UniProtQA huggingface dataset:
Protein: LPXK_ALKEH
Sequence: MSELPAFWLRRPPDWRAHALRPLAALYGGVMRLRRYGYRKGWIRRGRLPVPVVVVGNIFVGGTGKTPLVAWIADTLAAMGRRPGIVSRGYGGRSREWPRRVAADSDPAEVGDEPLLLARGTGCPVAVGPDRVAAAQLLLAAGCDVVVSDDGLQHYRLPRALELVVCDGHRGLGNGLCLPAGPLREPADRLADVDMVISNGRAPALTPWWFELVPGPLRPLAADAAPEGGPEPGTTVHAVAGIGHPARFFATLEGLGYRVIPHPFPDHHPYRAGELRFGDDRPVIMTEKDAVKCAGLAPARSWFLPVEARPEPATRERLEASLARLHSLTNR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: PUR7_PROM4
Sequence: MKKQPGSFLFDGKAKTIFTTDKPYELLVHFKNDATAFNALKHAELEGKGKLNCQISASLFQLLEKEGVPTHFLGVQDETWMLVQKVDVIPLEIVVRNIACGSLCKETPLERGEKLSSPLLDFYYKDDQLGDPLLTDARLNLLGLTTSGQRLEIQSIAFKVNNILKNFFQKIDLLLVDFKLEMGLNNAGELLVADEISPDSCRLWDQRSDDPEQRILDKDRFRQDLGGVVEAYGEILKRIQGNP
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: Y101_UREPA
Sequence: MAKYIKTGVSYINLDNARTINILPEDIDSYLELGGDEAYKTSDLGSELYINYADFESTNILFDLKKEELQAKIDAFLISNDTVLDLSEVFLDIHFSEDDDYEEDCCCEDECCSDEENEACCNSEVKVEEECCGGAKDDCCGGHEHEHEVCCDSETKTSETQEECCGGTKDDCCGGHEHEHHHHHSHQH
What are the official names of this protein?
Uncharacterized protein UU101.
Protein: XYLA_CLAMS
Sequence: MALTPTREDKFSFGLWTIGYTGADPFGGPTRSDLDVVEGVERISELGAYGLTFHDDDLFAFGSTDAERQTQIDRLKGALSDTGIVVPMVTTNLFSAPVFKDGGFTSNDRAVRRFAIRKVLRNIDLAAELGAKTFVMWGGREGAEYDSAKDVRGALERYREAVNLLGDYVTDKGYDIRFAIEPKPNEPRGDILLPTLGHALAFIETLERPELVGVNPEVGHEQMAGLNFTAGIMQALYQGKLFHIDLNGQRGIKYDQDLVFGHGDLQNAFSLVDLLENGGVGGGRSYDGPRHFDYKPSRTEDITGVWDSAAANMRMYLLLKERAQAFRADPEVQEALAAAKVAEIDTPTLNEGESYDDILADRSSYEDFAADEYFDAKGFGFVRLNQLALEHLMGARS
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_BARVE
Sequence: MADTTGRIPLWVIGTVAGILVIGLIGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLYA_RICM5
Sequence: MNIFNKNLHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGSLLTNKYAEGYPSKRFYNGCEEVDKAENLAIERVKKLFNCKYANVQPHSGSQANQAVYLALLQPGDTVLGMSLDSGGHLTHGAAPNMSGKWFNVVSYSVNKETYLIDYDEIERLADLHKPKLLIAGFSAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLRGPRGGLILSNDEEIGQKINSALFPGLQGGPLMHIIAAKAVAFLENLQPEYKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKFAANSLDRAGITCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGYMVADILDGLKNNEDNSDLEQKVLNEVTKLIKLFPFYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAT_ECO5E
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: AMI4G_ARATH
Sequence: MVALRFFFFSSLLILLILSQALIMSVGSASQIRLSSTFSIQEATIEDIRVAFNEKRLTSKQLVELYLEAISKLNPILHAVIETNPDALIQAEIADRERDLKNTTKLPILHGVPVLLKDSISTKDKLNTTAGSFALLGSVVARDAGVVKRLRESGAVILGKASLSEWAHFRSFSIPDGWSARGLQGKNPYVLSANPSGSSSGSAISVTANLVAVSLGTETDGSILSPASQNSVVGIKPSVGLTSRAGVVPISLRQDSIGPICRTVSDAVHLLDAIVGYDPLDEATKTASEFIPEGGYKQFLTTSGLKGKRLGIVMKHSSLLDHHIKTLRREGAIVINNLTIPNIEVIVGGTDSGEEIALLAEFKMSLNAYLKELVKSPVRSLADVIAYNEEFAEQEKVKEWGQEVFLTAEATSGMGEKEKTALQKMKELSRNGIEKLIEENKLDAIVTLGSDLSSVLAIGGYPGINVPAGYDSGGVPYGISFGGLRFSEPKLIEIAFAFEQATLIRKPPKFIA
What are the official names of this protein?
Probable amidase At4g34880.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: DRC10_BOVIN
Sequence: MALDVLTVAPLYQGPDINKIRLIAQTTKKSTIPPKALTPARSKLTTIETKRIMSVLDETIHKVELVSLLSHAASESKTSEGMLGPDIAKAVREHEDLCQALLDRVSYLQEEERKLQEAEDFEDEAWFRERLFAMDLQKSQLPPLMQEIKESTKNVVRLLLSNPQAASLLQAQTLGRSKEAQCFIDSLVELRGFLFEKLLTSPMEARDKIQFIQDITRRNRRHQEIIDTLENELAACVRNRNAEVEKENFVIQELKNHLHQVLRFSENSLLRTKQEAEKQQKADFRASQARVATVQQEILVLQSQFYNLVMENRDTEQALRKKKYKVETEIENWIQKYDSEMSEKQDEYEELDIIHKEEQLQLEELKKRHDVLVEEFSQIQAEREILTKKRLEDEQEMVRMVRAATLIQALWKGYLVRSMLKSKKKKRGKGKGEKKGKGKGKGKK
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
What are the official names of this protein?
Dynein regulatory complex protein 10, IQ domain-containing protein D.
What is the protein family that this protein belongs to?
Belongs to the DRC10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: SOX11_RAT
Sequence: MVQQAESSEAESNLPRDALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRPRKKPKTDPAAKPSAGQSPDKSAAGAKAAKGPGKKCAKLKAPAGKAGAGKAAQPGDCGAGKAAKCVFLDDDDEEDDEDDELQLRPKPDADDDDDEPAHSHLLPPPAQQQPPQLLRRYSVAKVPASPTLSSAAESPEGASLYDEVRAGGRLYYSFKNITKQQPPPAPPALSPASSRCVSTSSSSGSSSGSGAEDADDLMFDLSLNFSQGAHSACEQPLGAGAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWLEANFSDLVFTY
What is the function of this protein?
Transcription factor that acts as a transcriptional activator (By similarity).  Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity).  Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity).  Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity).
What are the official names of this protein?
Transcription factor SOX-11.
What are the subcellular locations of this protein?
Nucleus.
Protein: COB22_ARATH
Sequence: MPLRLEIKRKLAQRSERVKSVDLHPTEPWILASLYSGTLCIWNYQTQVMAKSFEVTELPVRSAKFVARKQWVVAGADDMYIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWEKGWACTQIFEGHSHYVMQVTFNPKDTNTFASASLDRTIKIWNLGSPDPNFTLDAHQKGVNCVDYFTGGDKPYLITGSDDHTAKVWDYQTKSCVQTLEGHTHNVSAVCFHPELPIIITGSEDGTVRIWHATTYRLENTLNYGLERVWAIGYIKSSRRVVIGYDEGTIMVKLGREIPVASMDNTGKIIWAKHNEIQTANIKSIGADYEVTDGERLPLSVKELGTCDLYPQSLKHNPNGRFVVVCGDGEYIIYTALAWRNRSFGSGLEFVWSSEGECAVRESSSKIKIFSKNFQEKRSIRPTFSAEKIFGGTLLAMCSSDFICFYDWAECRLIQRIDVTVKNLYWADSGDLVAIASDTSFYILKFNRDLVTSHFDSGRPTEEEGVEDAFEVLHENDERVRTGIWVGDCFIYNNSSWKLNYCVGGEVTTMYHLDRPMYLLGYLASQSRVFLVDKEFNVIGYTLLLSLIEYKTLVMRGDLDKASEILPTIPKDQHNSVAHFLESRGMIEDALEIATDPDYRFELAIQLGRLEIAQEIAVEVQSESKWKQLGELAMSSGKLQMAEECMKYAMDLSGLLLLYSSLGDAEGVTKLATLAKEQGKNNVAFLCLFMLGKLEDCLQLLVESNRIPEAALMARSYLPSKVSEIVALWRKDLSKVNSKAAESLADPEEYSNLFEDWQVALSVEAKAVETRGVYTGAKDYPSHADKSSMTLVEAFRNLQVEEEESLENGDMDHEEVVAEENGNEQRNEDDVAEHVEEHHEEKEAEEEEGIVDGDSTDGAVLVNGSEADEEWGTNNEGNPSA
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit beta'-2, Beta'-coat protein 2, Beta'-COP 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat COPB2 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: TRM3_HHV11
Sequence: MFGQQLASDVQQYLERLEKQRQLKVGADEASAGLTMGGDALRVPFLDFATATPKRHQTVVPGVGTLHDCCEHSPLFSAVARRLLFNSLVPAQLKGRDFGGDHTAKLEFLAPELVRAVARLRFKECAPADVVPQRNAYYSVLNTFQALHRSEAFRQLVHFVRDFAQLLKTSFRASSLTETTGPPKKRAKVDVATHGRTYGTLELFQKMILMHATYFLAAVLLGDHAEQVNTFLRLVFEIPLFSDAAVRHFRQRATVFLVPRRHGKTWFLVPLIALSLASFRGIKIGYTAHIRKATEPVFEEIDACLRGWFGSARVDHVKGETISFSFPDGSRSTIVFASSHNTNGIRGQDFNLLFVDEANFIRPDAVQTIMGFLNQANCKIIFVSSTNTGKASTSFLYNLRGAADELLNVVTYICDDHMPRVVTHTNATACSCYILNKPVFITMDGAVRRTADLFLADSFMQEIIGGQARETGDDRPVLTKSAGERFLLYRPSTTTNSGLMAPDLYVYVDPAFTANTRASGTGVAVVGRYRDDYIIFALEHFFLRALTGSAPADIARCVVHSLTQVLALHPGAFRGVRVAVEGNSSQDSAVAIATHVHTEMHRLLASEGADAGSGPELLFYHCEPPGSAVLYPFFLLNKQKTPAFEHFIKKFNSGGVMASQEIVSATVRLQTDPVEYLLEQLNNLTETVSPNTDVRTYSGKRNGASDDLMVAVIMAIYLAAQAGPPHTFAPITRVS
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: UDPE_NPVSL
Sequence: MKMIILVVSLHVLRNSAAVRVLCMFPTPSYSHQTVFDVYVNALLRRGHSLVVISPKIHNHNHGHRHHRHENLTEIDVGSVTNNFFKRLLQDSKVSRKRGIVSDSSTVTRVNYLGLARMISAQFEHEQVKRLLRSNQTFDVIVIEAFVSYPLILSYFFKDTPVIQISSGHGTAENFETMGAVARHPVYYPNMWRDRFKGLSVWQTVRQVFTEIRLYMEFSQLDADQSAMMKRQFGSKVPDVDALRKNVHMMFVNTHPVFDTNRPVPSNVQYLGGIHIDPAVTSVADEIDNDLAEFLENSTMGVVYVSLGSSVRASDMDSNMLNVFVETFRSIPYRVLWKVDKSDKIFDNIPSNVLIQRWFPQRRVLKHRNVKVFITQGGVQSTDEAIDAGVPMFGVPIMGDQFYNVYMYETYGIGRGVDTLTVDARQLTEIVMDVADNEKYKNGTLWLRDAIMDQPMRPLEKAVWYTEHVARRKGAKKHLGTRAANVTYSKYAMFDLILPMLITIFSTYLQKILSI
What is the function of this protein?
Catalyzes the transfer of glucose from UDP-glucose to ecdysteroids which are insect molting hormones.  Expression of egt interferes with normal insect development and block molting (By similarity).
What are the official names of this protein?
Ecdysteroid UDP-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: TRMFO_THEMA
Sequence: MIVNVIGAGLAGSEVAYNLGKRGIRVRLFEMRPKKMTEVHKTGYFAELVCSNSLKSEDITNAEGLLKAEMRLMGSITLEAAEKARVPSGKALAVDRNIFAKEVTEVIERLESVEIIREEVTEFDPEEGIWVVATGPATSDGLLPFLKKLLGDDLLFFFDAVSPIVTFESIDMECAFWGDRFGKGKDYINCPLTKEEYEEFWKALVEAEVIEMEDFDRKLLFERCQPIEEIARSGKDALRYGPLRPTGLVDPRTGKEPYAVVQLRREDKEGRFYSLVGFQTRLKWSEQKRVLRKIPCLRNAEIVRYGVMHRNVYINSPKLLDIFFRLKKHPNIFFAGQITGVEGYMESAASGIYVAYNVHRILKGLSPLKLPEETMMGALFSYIIEKVEGDLKPMYANFGLLPPLKVRVKDKFEKRKKLAERAIETMKKFLEENPW
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_XYLFT
Sequence: MPTEANTYDPQRIESTAQHYWDSTHAFEVNEHSNKPKYYCLSMLPYPSGALHMGHVRNYTIGDVISRYKRMTGHNVLQPMGWDAFGLPAENAAIKNKVAPAQWTYKNIERMRTQLKSLGYAINWSREFATCQPDYYVHEQHMFTRLMRKGLAYRRNALVNWDPVDQTVLANEQVIDGRGWRSGAPVEKREIPQWFLRITDYAQELLDGLNTLDDWPEPVKTMQRNWIGRSEGLEIRFEVRDVDNNALEALRVFTTRPDTLFGVTFVSIAPEHPLALHAAKSNPGLAGLLTQMKQGGLSEAELKTQEKRGMDTGLKAIHPITNEQLPVWVANFVLMAYGTGAVMAVPGHDQRDQEFANKYGLPIRQVIALKEPKNQDESTWEPDVWRDWYADKTREFELINSAEFDGLDYQGAFEVLAERFERQGRGQRRVNYRLRDWGVSRQRYWGCPIPVIYCPTCGAVPVPENQLPVILPENVAFSGTGSPIKTDPEWRKTTCPECGGPAERETDTFDTFMESSWYYARYTSPNAREMLDKRANYWLPVDQYIGGIEHAILHLMYFRFYHKLMRDARLVDSDEPAINLLTQGMVIAETFYRKNPDGSKDWINPADVNVECDERGRITGATLISDGQPVLIGATEKMSKSKNNGVDPQIMVTKYGADTVRLFSMFAAPPEQSLEWNETGVEGMARFLRRLWTQVHHHASHGPATALDITALDTAQKAIRCKTHNTIARVEDDYGRRRSFNTAIAAVMELSNTLARFDDTTTQSHAVRQEALETMVLLLNPITPHTSHALWQTLGHPETLLEDLPFPKVDTTALVRETAILAVQINGKLRGTIEVATDAPREHIENNALTEPNTARFLEGLTVLKIIIVPGKIVNIVAR
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT2C1_MOUSE
Sequence: MKVARFQKIPNVENETMIPVLTSKRASELAVSEVAGLLQADLQNGLNKSEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISILMRQFDDAVSITVAIVIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSVDESSLTGETAPCSKVTAPQPAANGDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYNSKGQTLALTQQQRDLYQQEKARMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAIAIASRLGLYSKTSQSVSGEEVDTMEVQHLSQIVPKVAVFYRASPRHKMKIIKSLQKNGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVSEIIKKVERSREKVQKNAGSASSSFLEV
What is the function of this protein?
ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway (By similarity).  Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side.  The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state (By similarity).  Plays a primary role in the maintenance of Ca(2+) homeostasis in the trans-Golgi compartment with a functional impact on Golgi and post-Golgi protein sorting as well as a structural impact on cisternae morphology.  Responsible for loading the Golgi stores with Ca(2+) ions in keratinocytes, contributing to keratinocyte differentiation and epidermis integrity (By similarity).  Participates in Ca(2+) and Mn(2+) ions uptake into the Golgi store of hippocampal neurons and regulates protein trafficking required for neural polarity (PubMed:19793975).  May also play a role in the maintenance of Ca(2+) and Mn(2+) homeostasis and signaling in the cytosol while preventing cytotoxicity (By similarity).
What are the official names of this protein?
Calcium-transporting ATPase type 2C member 1, ATPase 2C1, ATP-dependent Ca(2+) pump PMR1, Ca(2+)/Mn(2+)-ATPase 2C1, Secretory pathway Ca(2+)-transporting ATPase type 1, SPCA1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Note=During neuron differentiation, shifts from juxtanuclear Golgi position to multiple Golgi structures distributed over the neural soma with a predominance in the apical dendritic trunk.
Protein: PYRG_JANMA
Sequence: MTKFVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFITAKMRKVNNFTTGQIYESVIRKERRGEYLGKTVQVIPHITNEIQDYIHRGAEGFDVALVEIGGTVGDIESLPFLEAARQLSLRAGRNAAAFVHLTLVPYLASAGELKTKPTQHSVQKLREIGISPDALLCRADRQIPDDERAKISLFSNVQEDAVISVWDADTIYKIPQMLHDQGLDRIVCEKLALSPKPADLSMWTKLVHSLENPKDSVTIGMVGKYVDLTESYKSLTEALRHAGIHTESRVNIEYLDSEEIENTGPQCLAKYDAILVPGGFGKRGVEGKIASARFARESKIPYLGICLGMQVALIEYARDVAGLTKANSTEFDADTEQPVVALINEWQNHDGKVERRDANSDLGGTMRLGAQTCAVKPGTLAAEIYGSEVTERHRHRYEANNHYLGRVEDAGLIVSARTPTESLCEIMELPRTVHPWYVGVQYHPEFKSTPRDGHPLFISFIKAALAHKHAGQAKK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RIMO_CUPMC
Sequence: MSSDTNLSNPPKVGFVSLGCPKALVDSEQIITQLRAEGYSISGTYDGADLVVVNTCGFIDEAVQESLDAIGEALTENGKVIVTGCLGAKKDAAGHDIVSAVHPKVLAVTGPHALGEVMQAVHTHLPKPHDPFTDLVPAAGIKLTPKHYAYLKISEGCNHRCSFCIIPSMRGDLVSRPVAEVMLEAENLFKAGVKELLVISQDTSAYGVDVKYRTGFWNGRPLKTRMTELVAALGELASQYGAWVRLHYVYPYPHVDEIIPLMNQGNVLPYLDVPLQHAHPDVLKRMKRPANAEKTLDRIRAWREVCPDLTIRSTFIAGFPGETEEEFQTLLDFIAEAELDRVGCFAYSPVEGATANDLPGALPDEVREERRARFMEVAEEVSARRLQRKVGQTLRVLVDEVNQDGGIGRSSADAPEIDGLVYIDPAAKASQRYKTGDFVNVKITGADGHDLWGEVA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BURS_ANOGA
Sequence: MKSTFLVVLELAFFLLPGRVLYAQKDSEDGGSHYSSDDCQVTPVIHVLQYPGCVPKPIPSFACIGRCASYIQVSGSKIWQMERSCMCCQESGEREASVSLFCPKAKNGEKKFRKVSTKAPLECMCRPCTGIEDANVIPQELTSFADEGTLTGYFQKSHYKSIE
What is the function of this protein?
Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading.
What are the official names of this protein?
Bursicon, Bursicon subunit alpha, Cuticle-tanning hormone.
What are the subcellular locations of this protein?
Secreted.
Protein: FIS_VIBC1
Sequence: MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVTELYELVLAEVEQPLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: HIS6_SORC5
Sequence: MLAKRIIPCLDVKDGRVVKGVRFVGLRDAGDPVEAARRYDAEGADEITFLDITASHEKRGIILDVVARTAEVLFTPLTVGGGVKSEQDIKALLDAGADKVAINTAAVNDPDLVRRAADRWGAQAIVVAIDARRIADPSRVAWTVVTHGGRRDTGRDAVAWAEEIARAGAGELLVTSMDRDGTRDGYDLLLTAAIARAVPVPVIASGGVGTLDHLRAGLVEGGADAALAASIFHDAEYTIGEAKAYLEAAGVPVRPARAGGPGDAASRGRS
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2013_XENLA
Sequence: MWLQQRIKVFPGLLSSSWARRVLAVSGFLVIIYWYIFSGSHYRSFWYSGKQWGVSGACLQAQIVQWKTLAEKGDVVMVSFPGEEIKLQGPAMVGNGQIIVDVGKNNLWVSSLSVLFHLTNYSPLTLFKNVGALAETHATAIFLKEGLIRTIRCLQVEASDSPRDCVTVREDHFAHRSRPHVYVQNIHITNPSDRVVTFDISSQKPLTGETFSTSLEKVQEKQFLLSSGRVSVEDGKIILVVVATKKLASRLQVSPKSEHDETVLSVVYASEPIDPAKLSDTFSKLRENAKKEMFELMHMKTEDLFHEHQQIWSDLIVSGIEMKKITDLHTPSRDTINITLYYMLSCSLAPLVDPALSNEEREKMESFLNYADHCFTGHSSMHAENLWPGSLSGITQLLQLWDLWKLTLQKRGCKSLVSAGAHGLMQGMLLSFGGLQFTENHLQFQSDPHVLHNSYSLRGIHYNKDLINLAVLLDQDEKPFLHVSVKFQDKLVKLYACEAGCLNEPVELTSEVRGHIFPVLITQPLTPLLYISTDLTHLQDLRHTLHLKEILAHEEHMAKQYRGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKV
What are the official names of this protein?
Uncharacterized protein KIAA2013 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CDKD1_ARATH
Sequence: MEQPKKVADRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKELKHPHIIELIDAFPHKENLHIVFEFMETDLEAVIRDRNLYLSPGDVKSYLQMILKGLEYCHGKWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFGAKQYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDYVEYQFVPAPSLRSLLPTVSEDALDLLSKMFTYDPKSRISIQQALKHRYFTSAPSPTDPLKLPRPVSKQDAKSSDSKLEAIKVLSPAHKFRRVMPDRGKSGNGFKDQSVDVMRQASHDGQAPMSLDFTILAERPPNRPTITSADRSHLKRKLDLEFL
What are the official names of this protein?
Cyclin-dependent kinase D-1, CDKD;1, CDK-activating kinase 3-At, CAK3-At.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPR_ALIFM
Sequence: MSGSAKYSDWSQVMTLIANAAEQGNHQPLLTMLMTPDEREALVARVNIFHELLQGELSQRQISQLLGVGVATITRGSNELKSHTDEEKVWLMDLLEKSTKNELDVEKE
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
What are the official names of this protein?
Trp operon repressor homolog.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.