PharMolix/UniProtQA huggingface dataset:
Protein: SERC_XANC5
Sequence: MTRAFNFSAGPATLPESVLRQAQAEMVEWNGVGASIVEISHRSADFMAVAAAAEADLRSLLSIPDDYAVLFTAGGATTIQALLPLNFAAPGQAADYVITGHWGKTAIKQAATSVDARIAADAQADGFVDIPPAASWTLSPHSAYVHITANETIHGVEFRDTPDVGTLPLFADFSSSIASEPLDISRYGLIYAGAQKNLGPVGISVVIVRRDLLERAGQPRADIFNYASHAARDSMLNTPPTWNWYVLGLTVKWMLEQGGVQEFARRNAEKAALVYGAIDGSGGFYRNLIKPAVRSRMNIPFFLPDEQLDALFVSESKAAGLLALKGHKAVGGIRASLYNAMPVAGAQALAAFMHDFQQRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_OSTTA
Sequence: MENSAFFYGVFLWCLLISVTGYSIYIGFGPPSKELRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: XDH_HUMAN
Sequence: MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV
What is the function of this protein?
Key enzyme in purine degradation.  Catalyzes the oxidation of hypoxanthine to xanthine.  Catalyzes the oxidation of xanthine to uric acid.  Contributes to the generation of reactive oxygen species.  Has also low oxidase activity towards aldehydes (in vitro).
What are the official names of this protein?
Xanthine dehydrogenase/oxidase.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome. Secreted.
Protein: TF2B1_SACS2
Sequence: MLYLSEENKSVSTPCPPDKIIFDAERGEYICSETGEVLEDKIIDQGPEWRAFTPEEKEKRSRVGGPLNNTIHDRGLSTLIDWKDKDAMGRTLDPKRRLEALRWRKWQIRARIQSSIDRNLAQAMNELERIGNLLNLPKSVKDEAALIYRKAVEKGLVRGRSIESVVAAAIYAACRRMKLARTLDEIAQYTKANRKEVARCYRLLLRELDVSVPVSDPKDYVTRIANLLGLSGAVMKTAAEIIDKAKGSGLTAGKDPAGLAAAAIYIASLLHDERRTQKEIAQVAGVTEVTVRNRYKELTQELKISIPTQ
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB 1, TFIIB 1.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: RPOB_ECOL5
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLSPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: AES_SALTY
Sequence: MKPENKIPVLTRLSDEMTAVVNFQQPGLPPWPADGDIETQRQYYLLERRFWNADAPSMTTRTCAVPTPYGDVTTRLYSPQPTSQATLYYLHGGGFILGNLDTHDRIMRLLARYTGCTVIGIDYSLSPQARYPQAIEETVAVCSYFSQHADEYSLNVEKIGFAGDSAGAMLALASALWLRDKHIRCGNVIAILLWYGLYGLQDSVSRRLFGGAWDGLTREDLDMYEKAYLRNDEDRESPWYCLFNNDLTRDVPPCFIASAEFDPLIDDSRLLHQTLQAHQQPCEYKMYPGTLHAFLHYSRMMTIADDALQDGARFFMARMKTPR
What is the function of this protein?
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons).  Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate.  Negatively regulates MalT activity by antagonizing maltotriose binding.  Inhibits MelA galactosidase activity.
What are the official names of this protein?
Acetyl esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_ECOLC
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RACYT_RANTE
Sequence: MFTMKKTLLVLFFLGVVSLSLCVEERDADEEDGGEVMEEEVKRGALRGCWTKSYPPKPCKGK
What is the function of this protein?
Has antibacterial activity against Gram-positive bacteria B. megaterium Bm11, S. lentus and M. luteus, and Gram-negative bacteria E. coli D22, Y. pseudotuberculosis YP III and P. syringae pv tabaci, and antifungal activity against C. albicans ATCC 10231, C. tropicalis, C. guiller-mondii and P. nicotianae spores.  Has weak hemolytic activity.  The mature peptide inserts into the hydrophobic core of the bacterial cell membrane and increases permeability without disrupting membrane integrity.  Probably binds to the outer membrane surface before aggregating to form transmembrane pores.
What are the official names of this protein?
Ranacyclin-T.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARID6_ARATH
Sequence: MVDTEMQEQDVTFGALVETKYLEEEPLEPENDHNPSEIPQPLLLGDGQANNGHGMNGGAVGVVDHSERKTRRVQMLSPKTEGENAKKRKTWLLDSEAQGTDEAGTPVEQVAFLREVEAFYKESFLEFKPPKFYGQPLNILKLWRAVVNLGGYEVVTTNKLWRQVGESFNPPKTCTTVSYTFRNFYEKALLEYEKCLRNNGELNLPGSTLILSSSVEKEPSSHQGSGSGRARRDSAARAMQGWHAQRLVGSGEVTAPAVKDKGLISTPKHKKLKSIGLQKHKQQTSMDHVVTNEADKQLAAEVVDVGPVADWVKINVKESKDSFEIFALVPGLLRKEVRIQSDPAGKVVITGQPEQLDNPWGITPFKKIVDLSARIDPLHTSAVMSMHGRLFIRVPFEQ
What are the official names of this protein?
AT-rich interactive domain-containing protein 6, ARID domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTUD4_HUMAN
Sequence: MEAAVGVPDGGDQGGAGPREDATPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIVMELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSRKVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSVSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQYHRNVRGRPFRGDRRRSGMGDGHRGQHT
What is the function of this protein?
Deubiquitinase which hydrolyzes the isopeptide bond between the ubiquitin C-terminus and the lysine epsilon-amino group of the target protein (PubMed:23827681, PubMed:25944111, PubMed:29395066).  May negatively regulate inflammatory and pathogen recognition signaling in innate immune response.  Upon phosphorylation at Ser-202 and Ser-204 residues, via IL-1 receptor and Toll-like receptor signaling pathway, specifically deubiquitinates 'Lys-63'-polyubiquitinated MYD88 adapter protein triggering down-regulation of NF-kappa-B-dependent transcription of inflammatory mediators (PubMed:29395066).  Independently of the catalytic activity, acts as a scaffold for alternative deubiquitinases to assemble specific deubiquitinase-substrate complexes.  Associates with USP7 and USP9X deubiquitinases to stabilize alkylation repair enzyme ALKBH3, thereby promoting the repair of alkylated DNA lesions (PubMed:25944111).
What are the official names of this protein?
OTU domain-containing protein 4, HIV-1-induced protein HIN-1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Primarily cytoplasmic.
Protein: HIS7_ZYGBA
Sequence: MIGEHKALVQRITNETKIQIAISLNGGHIELPESILDKNPTQENNIATQATTSQVIDIHTGVGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGEAFKQALGQVRGVKRFGCGFAPLDEALSRAVVDLSNRPYAVIDLGLKREKIGDLSCEMIPHFLESFIEAARLTVHIDCLRGFNDHHRSESAFKALAVAIREATAPNGTNDVPSTKGVLM
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
Protein: RS4_METTH
Sequence: MGHPRKARKKYDTPPHPWNAERIKEENRLVAKYGLKNKKEVWKAETMVRRYRRDARYLLGMASEHTGKEREQLLGHLVRTGILNEGAKLEDVLDLTVEDVLRRRLQTLVHKRGLARTVKEARQMVIHGHIALDGRKIDAPGYIVKRGEEDKIGFYPSSPMKKQIEAAQDAE
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: VP35_MABVR
Sequence: MWDSSYMQQVSEGLMTGKVPIDQVFGTNPLEKLYKRRKPKGTVGLQCSPCLISKSTSTDDIVWDQLIVKKTLADLLIPINRQMSDIQSTLSEMTTKVHEIERQLHDITPVVKMGKTLEAISKGMSEMLAKYDHLVISTGRTTAPAAAFDAYLNEHGVPPPQPAIFKDLGVAQQAYSQKTMVKNQTTDAADKMSKVLELSEETFSKPNLSAKDLALLLFTHLPGNNTPFHILAQVLSKIAYKSGKSGAFLDAFHQILSEGENAQAALTRLSRTFDAFLGAVPPVIKVKNFQTVPRPCQKSLRAVPPNPTIDKGWVCVYSSEQGETRALKI
What is the function of this protein?
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.
What are the official names of this protein?
Polymerase cofactor VP35, Marburg VP35, mVP35.
What is the protein family that this protein belongs to?
Belongs to the filoviridae polymerase cofactor VP35 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CYTS_RAT
Sequence: MAYLLHAQLFLLTTFILVLNMRLCPVLGHFLGGIEKSSMEEEGASEALNYAVNEYNEKNSDLYLSRVVEVKDVQKQVVAGTKFFFDVILGKTICLKTQGDLTNCPLNEEADQQEHEFCSFVVHDIPWENYIVLLSSSCHSI
What is the function of this protein?
This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain.  Papain is inhibited non-competitively.
What are the official names of this protein?
Cystatin-S, Cystatin-1, Protein LM.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SERC_PSEU2
Sequence: MSKRAFNFCAGPAALPEAVLLRAQAELLDWHGKGLSVMEMSHRSDEFVSIATKAEQDLRDLLSIPSNYKVLFLQGGASQQFAQIALNLLPENGKADYIDTGIWSQKAIDEASRYGAINVAASAKAYDYFAIPGQNEWKLSKDAAYVHYAPNETIGGLEFNWIPETGDVPLVADMSSDILSRPLDISRFGMIYAGAQKNIGPSGIVVVIIREDLLGRARSLCPTMLDYKVAADNGSMYNTPPTLAWYLSGLVFEWLKEQGGVEAIGKRNEIKQRTLYDFIDASELYSNPINKPDRSWMNVPFRLADDRLDKPFLAGADANGLLNLKGHRSVGGMRASIYNAIDINAINALVAYMKDFEKEHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHU6_ECOLX
Sequence: MKKYDRGWASLETGAALLIVMLLIAWGAGIWQDYIQTKGWQTEARLVSNWTSAARSYIGKNYTTLQGSSTTTTPAVITTTMLKNTGFLSSGFTETNSEGQRLQAYVVRNAQNPELLQAMVVSSGGTPYPVKALIQMAKDITTGLGGYIQDGKTATGALRSWSVALSNYGAKSGNGHIAVLLSTDELSGAAEDTDRLYRFQVNGRPDLNKMHTAIDMGSNNLNNVGAVNAQTGNFSGNVNGVNGTFSGQVKGNSGNFDVNVTAGGDIRSNNGWLITRNSKGWLNETHGGGFYMSDGSWVRSVNNKGIYTGGQVKGGTVRADGRLYTGEYLQLERTAVAGASCSPNGLVGRDNTGAILSCQSGRWSGGNKINYSACNWYKSSVAMNHFIGGKSGGSIYYKPIQCPTGYIMTGTRMYGIGDGVDEEHVDAYCCPFN
What are the official names of this protein?
Shufflon protein C'.
Protein: KDUI_OPITP
Sequence: MKLHYSPSPAETKRLEPEQLRSAFLISDLFQPGQLITHYTDLDRMIAGGVTPTSAPLPLPNSKQATGTDFFLERREIGIINIGAPGAVRVGGKSYPLGSLDCLYVGKGERDVVFEAGSAGQAQYFFISTPAHMTYPTAHAARAQGTQPIGDPAKCNRRRINRYIHANGIKSCQLVMGFTEFEPGSVWNTMPPHTHSRRTEIYLYFDLGTDMVVHLMGEPQATRHLIVRDREAILSPAWSIHAGVGTGAYRFIWAMGGDNQTFEDMDQVAIADLK
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: RUVA_PHOPR
Sequence: MIGRLSGTILEKQPPEVLIDVGGIGYEVQMPMSCFYELPEVGQAAVICTHFIVREDAQLLYGFNKKSERELFREVIKANGVGPKLGLAILSAMTASQFVLSVENEDITTLVKIPGVGKKTAERLVIEMRDRLKGWGEGDLFTPASDAAASNAEIQKYSSARAEDEAVSALIALGYKALQAAKVVSQVVKPEMSSENIIREALRSMV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SYFA_COXBU
Sequence: MQNQLNALLQSAKKSVADAQSEIVLEEIRVDYLGKKGKLTELLKSVGQMPADQRPLLGKAVNEIKREIQQLLNAKSTQLREKSLQEKLNKEKVDITLRGRYDHLGAIHPISRVSERVSQLFSMLGFQIAEGPEIENEYYNFEALNIPADHPARTMADTFYFSGDKLLRTHTSPVQIREMEKQGVPIRLIALGRVYRRDLDQTHTPMFHQVEGLVIDKRSTFANLKGLLQQFLNCFFEKDVRLRFRPSYFPFTEPSAEVDIYQPRTDKWLEVLGCGMVHPNVLRNLNIDPDEYSGFAFGIGLDRLAMLRYEVTDLRLFFENDLRFLGQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIL5_SCHPO
Sequence: MASFGELSFLSEISNIHKSNKKHEIQSAGTVALDNGVESPYYICVQVENQGIEVYHMKDERLFASCPLPEKTRFSCSPIYIKEGNWHYIWTCTSLKSNGEWKILLWKFNDLEEESEVVYRDISNQQIFALHFISSTGQLVIVFRNGKIAFLDPEDDKVHMSASVNESATLLQSMYVPSQANPIDAVRLASNEASGTNNNPKEIEMNSDTTSSVPKSGSTSFSANVTSSTSMVYLLYSVHVDKIIQYYVDSFSVSERRLVNTRAVVLKEVQAPSHILMSKDSTSIYTISLEGLSIYSLHDESKSYMLIKILHFQSISKIEHIELISDNFLLIQHDSQLSLWDITFGTIQDVYDLKQKPTILTFTCYKSSLKKMNQNSQLTGYIAVLLKKGLAIVPYTLPIKMLLADAVGKRTSKIGKLRGTNELIGEGVLTKSKNGPSMRDQLLKNIQLQDHSLRDELISLRSLAEQKNTIEFDAKFLGVVERYQNQYANNCKILKTSSVLPIPFAHAIESLLFSLDEENELQVSCAASGTLNYLIRHRLFSYSTLVQKGFSGSVFDCLYKFQKDIAFNFLERTSDISAYEIACAIKTAINSSKVKLLRSALARLSLFDSTTSREALLLAFVPEDFDSLFKTLGNLVVDSNLASVKFNLETYIYCLSVVLDAMGVGGVASSSENLEAARILYNDLQEKLTNLTAMSLVLPAISEIVKRKKDVHAERVQFYANPQPKAIVDDMGDLATLLKKDFLSEKRKGKSQRARGKEIDMAIGKYTVERLEI
What are the official names of this protein?
Uncharacterized protein C1565.05.
Protein: PYRH_MYCGE
Sequence: MHKSNNKIRQRIIIKLSGAGLTKENSQPFSNDFFETIINQLKVLKESYQVGIVIGGGNIIRGNNCQEFNIAEYHGHQLGIIATVVNGYFLKAKLDAHNLKSALLSAISCPSLAVQILSQQTIDKAFEENDFVIFSGGTGNPYFSTDTALALRAVQTKAVAILIGKNGVDGVYTADPKKDKNATFLPTLNYDHAIKNDLKIMDITAFTMCKENNLKIIIFNINAENALLDALNKKGRFTIIENN
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS16_DICDI
Sequence: MIAAQWKIIGNSTYIKKEIYSMSWDVDLKQQVSVGSPFAGPIAVMRDSSKFVEMNSQNMKPYLKIFTASGDLISQMIWDSSKNIVAMDWIEKERLVIVLQNATVLIFNVFCEQMTQFSLGDIVREEEILECKIWSDGIVVLTSASQLYSVPSINDFFVESGRVIRLPPLPEEPKARPEWAILEPQFSLSQSIEIFMSINGTLYLIDEDKVESQLEATEPIQKMVVSPCGKKLACFDTKGTLLILKTDGSTTNPDRMDTKATKSPVLKWCGSDGVMMYWDSIKDPILFYFSKGDSWAKFTLDQPVSLVTEIDGLRIISDTTSEFFHKVSDVTIDIFKIGTTSPASILYDATDHFISKSPQADESIRSINDQLEDAVNDCILAAGFEFNGGEQSKLLKAASFGKCFLENYNPSQFVTMCRSLRVLNAVRHHEIGIPLSIKQYYHIGIEELIDRLISRRKHLLAWRICDYLKIKSDVVLNHWACTKVRTDIPDQELGKIIIKKLESVPGISFANIASAAYLAGRSKLATKLLEYEPKAAEQVPPLIKMGESGLALNKAIESGDTDLVYLVLLAMQRSLPLADFLELTFSKVVALDLLISMCKQKNDFPLLREIYHIKDQSKEMGNIYLQEALSSHPSQLDQRIKAYNKSIEHYHHSKDKDDQATSKFIDDQIKLEMLQKELETNLQDESFVGISINDTIYKLITMNQPKKAQSIRSEFKVPDKRFWWIKIKALSIMNDWEELMKFSKEKKSPIGYEPFVEVCLDQKNQIEALKYIPKITDILPKIQFYIQIGYFREAADIAFKEKNFDLLNLISRKCTNNEILNIIEQMKSQIRR
What is the function of this protein?
May play a role in vesicle-mediated protein trafficking to endosomal/lysosomal compartments and in membrane docking/fusion reactions.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 16 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS16 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein.
Protein: SSI_STRCO
Sequence: MRNTARWAATLGLTATAVCGPLAGASLASPATAPASLYAPSALVLTVGHGESAATAAPLRAVTLTCAPTASGTHPAAAAACAELRAAHGDPSALAAEDSVMCTREYAPVVVTVDGVWQGRRLSYERTFANECVKNAGSASVFTF
What is the function of this protein?
Strong inhibitory activity toward subtilisin BPN' and, to a lesser extent, toward trypsin.
What are the official names of this protein?
Subtilase-type protease inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL16_LISMO
Sequence: MLVPKRVKYRREFRGNMRGRAKGGTEVAFGEYGLQAVEASWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTSKPIGVRMGKGKGAPEGWVSPVKRGKIMFEIAGVPEDVAREALRLAAHKLPVKTKIVKREEIGGEANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: FENR_RICPR
Sequence: MYNTDIVIIGSGPVGLFAVFQAGMLGMKCHVIDAQEVIGGQCITLYPEKHIYDIPAYPKIAAKELIKQLESQAAPFNPVYHLNQQATELNKHDDFFEIKTSKNTLIKSKVIIIAAGAGAFGPNKPPIANIEAFEGKSIFYFINDKSKFLGKNIVVAGGGDSAVDWAITLSEIANKIYLVHRRDKFTAATESVRQLRHIAETGKIELVTGYQLNNLDGHNSELRSVIVKDLQNNIRKLDANILLPFFGLKQDLGPLANWGFNVRLQHIEVDNYYYQTNIKGIYAIGDVAHYVGKLKLIITGFAEAACSLHHAYSRVFDGKALHFEYSTNKYEQKQ
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: LSPA_ANADF
Sequence: MSARRPFSKWALLALLFVTLVAIDQWTKYLAVERLTTLFERTGAETLGERLAGFLEHQHLEPISTDPYYVWRPVWRMNYVENPGAAWGLFRGHSEAFRNGFFTLVSLGAVAFILHYYRKLRAEQRYLQVALALVLSGAVGNFLDRLARGYVIDFIEWYWWNRPDIRWPTFNIADSLIVVGVALLVLHPGSGKAAQKAGADAEGDRRASTGG
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYE_CITK8
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYFQTKRFDRYNAVIDEMLEAGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHGHEHHSDDEPCVVRFANPQDGSVIFDDQIRGSIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALNAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEIFTREEMIKLFSLNAVSKSASAFNTDKLLWLNHHYINSLAPEYVATHLQWHIEQENIDTRNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVRDKLAAITEWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKSRSIERINKALAFIAERENQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3240_VIBC1
Sequence: MYPHLTGLGIHDPKQIERYSLRQEAHKDVLKIYFHKQKGEFFAKSVKFKYPRQVKSVLVDSGSHKYKEVTEINRNLTLVIDELNKITKPAKTTEVDVKEKILSDLRHLEKVVSSKIAEIEADLEKLK
What are the official names of this protein?
UPF0325 protein VIBHAR_03240.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.