PharMolix/UniProtQA huggingface dataset:
Protein: NDHK_AETGR
Sequence: MNSIKFPVLDRTTKNSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRTKIAREIYKDQIRPQQGNRCFTTNHKFLIVRSTDTGNSDQELLYPPSSTSEISTETFFKYKSPVSSHELVNSGGV
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MUTS_BACSU
Sequence: MAGYTPMIQQYLKIKAEHQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGAAEKIPMCGVPYHSASAYIEQLIKKGYKVAICEQTEDPKAAKGVVKREVVQLITPGTVMDGKGIHESENNFIASVSACSNGYGLALSDLTTGENLAVLIERLEDVISEIYSVGAREIVVSGSLDADTVAQLRERCGATISIEDGETDEHVTIIEHLNNEDITKTFLRLYTYLKRTQKRSLDHLQPVQVYELEEAMKIDLYSKRNLELTETIRSKNKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRVNQIEERQEMVETLMSHFFEREDLRERLKEVYDLERLAGRVAFGNVNARDLIQLKESLKQVPGIKQLVASLAHDKAKERAKRIDPCGDVLELLEEALYENPPLSVKEGNLIKDGYNQKLDEYRDASRNGKDWIARLEQQEREYTGIRSLKVGFNKVFGYYIEVTKANLHLLEEGRYERKQTLTNAERYITPELKEKEALILEAENNICELEYELFTELREKVKQYIPRLQQLAKQMSELDALQCFATISENRHYTKPEFSKDEVEVIEGRHPVVEKVMDSQEYVPNNCMMGDNRQMLLITGPNMSGKSTYMRQIALISIMAQIGCFVPAKKAVLPIFDQIFTRIGAADDLISGQSTFMVEMLEAKNAIVNATKNSLILFDEIGRGTSTYDGMALAQAIIEYVHDHIGAKTLFSTHYHELTVLEDKLPQLKNVHVRAEEYNGTVVFLHQIKEGAADKSYGIHVAQLAELPGDLIARAQDILKELEHSGNKPEVPVQKPQVKEEPAQLSFFDEAEKPAETPKLSKKEKQVIDAFKSLNILDMTPLEAMNEMYKLQKKLH
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).  Overexpression of mutSL partially suppresses the high spontaneous mutation frequency of a ytkD/mutM/mutY triple disruption which lacks the system required to prevent damage by oxidized guanine (8-oxo-dGTP).  This suggests that MutSL also functions to repair mismatches due to oxidative stress in both growing and stationary phase cells.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: SPEH_AERPE
Sequence: MAQIPSSRTNGSGAQMRVFGLHVYGNFYECANTELLKSPEELEKVVLEAAREGGMTVLDIKSWKIGEGVSVVAIILESHITVHTWPEYRFATVDVYSCGGHTNPHRAFEVLAEALKPARVEKGVAERHLE
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: TRPB_AGRRK
Sequence: MNQTPKLNSFRAGPDEDGRFGIYGGRFVAETLMPLILDLQEEWEKAKNDPAFQAELKSLGTHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVIPVTAGSGTLKDAMNEALRDWVTNVDDTYYLIGTAAGPHPYPEMVRDFQAVIGTEAKQQMLEAEGRLPDLVIAAVGGGSNAIGIFHPFLDDESVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPGIGPEHSWLNDIGRAEYVPIMDHEALEAFQTLTRLEGIIPALEPSHALAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVAKILGM
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: UBC11_YEAST
Sequence: MAVEEGGCVTKRLQNELLQLLSSTTESISAFPVDDNDLTYWVGYITGPKDTPYSGLKFKVSLKFPQNYPFHPPMIKFLSPMWHPNVDKSGNICLDILKEKWSAVYNVETILLSLQSLLGEPNNRSPLNAVAAELWDADMEEYRKKVLACYEEIDDY
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2-18 kDa, E2 ubiquitin-conjugating enzyme 11, Ubiquitin carrier protein, Ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RLMN_CORDI
Sequence: MTNPTKPIPLNFDKPRRFMPPKHFADLSADERIDALKELGLPKFRANQIARHYYGRLEADPSTMTDLPAAAREKVKDALFPQLMQPVRAVQADDGETQKTLWKLHDGTLLESVLMRYPNRATLCISSQAGCGMACPFCATGQGGLDRNLSTGEIVDQVRAASATMQAEGGRLSNIVFMGMGEPLANYKRVVSAVRQITAPVPEGFGISQRNVTVSTVGLAPAIRKLADEDLSVTLAVSLHTPDDELRNTLVPTNNRWEVAEVLDAARYYADRSGRRVSIEYALIRDVNDQGWRADMLGKKLHKALGPLVHVNLIPLNPTPGSKWDASPMDRQKEFVQRVIAQGVTCTVRDTRGQEIAAACGQLAAEER
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_SHISS
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACR1A_ACTEQ
Sequence: MNQVMTIFLVLGVIVYSVESSLTPSSDIPWEKCRHDCFAKYMSCQMSDSCHNKPSCRQCQVTYAICVSTGCP
What is the function of this protein?
Toxin that is lethal to crab.  It interacts with divalent metal ions (zinc and nickel) suggesting it may function as a metal ion chelator to regulate metal ion levels or as a metal ion transporter, or that its function is modulated by metal ions.  Is not active against any of the voltage-gated potassium and sodium channels tested.  In addition, it does not show activity in bacterial and fungal growth inhibitory assays as well as in hemolytic assays.
What are the official names of this protein?
U-actitoxin-Aeq5b, U-AITX-Aeq5b, Acrorhagin Ia, Acrorhagin-1a.
What is the protein family that this protein belongs to?
Belongs to the Acrorhagin I family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RLMKL_SHEFN
Sequence: MFNFFAAAPKGFEYSLASELKEFGATDVKESVAGVYFSASLELAYRITLWTRLASRIVLVIYKGACDSAEQLYNAAYCIDWPSHFSHKKTFSIDFHGTGGFINNTQFGALKIKDAVVDRFRDDGTPRPDVERVNPDFKIDAHYRNGQLTISMNFSGASLHQRGYRSTTGEAPLKENLAANMLVRSGWQANPITVLDPFCGSGTVLIEAALMAADIAPGLKREKFGFENWQSHNKAMWQVIFDEAQARATLGKTRCKLKFYGSDIEPHLISIAKRNAENAGVAELIEFSVSDALDVTPPVSEGFLISNPPYGERLGNVTELLQLYYQLGDKFKKEFGGWKIAMLCSDVELISSLKLKADKQMKMFNGALECAFNIYTLHANSTRRDVPELPEGVDIIDIAPAFANRIKKNVKQFEKWAKKERIDSYRLYDADLPEYNVAIDRYVDYVVIQEYSAPATIPEAVTKRRISDVLLALPGALGIHPDRITLKTRERQKGANQYQKIDERKVEVITEEYGAKFKLNLTGYLDTGLFLDHRVTRKLVGDKAKGKNVLNLFAYTGSASVHAAIGGAKSVTTIDMSNTYINWAKENFALNGLSGAKYDFIQADCLQWIKDNSHQKYELIFIDPPTFSNSKRMEDSWDVQRDHAEMLGGLIKLLSPNGELIFSNNKRKFKMDIEALNQAGIDVTNIDHLCLPLDYKRNPHIHNVWLLTHAKK
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_MANSM
Sequence: MKKSIIIPALDLIDGNVVRLHQGDYAKQTTYSDNPIEQFASYLAQGAEQLHLVDLTGAKDPAKRQTALIGKIIAATHCKIQVGGGIRTEKDVADLLAVGANRVVIGSTAVKERAMVKEWFNKYGAEKFVLALDVNIDASGQKIIAISGWQEASGVSLEELIEDFQSVGLQHVLCTDISRDGTLAGSNVDLYKEICAKYPAVNFQSSGGIGSLEDIKALKGTGVAGVIVGRALLEGKFNVAEAIECWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUR3_ARATH
Sequence: MATCPPFDFSTKYYDGDGGCQRQSSFFGGTTVLDQGVGYAVILGFGAFFAVFTSFLVWLEKRYVGARHTSEWFNTAGRNVKTGLIASVIVSQWTWAATILQSSNVAWQYGVSGPFWYASGATIQVLLFGVMAIEIKRKAPNAHTVCEIVKARWGTATHIVFLVFCLATNVVVTAMLLLGGSAVVNALTGVNLYAASFLIPLGVVVYTLAGGLKATFLASYVHSVIVHVALVVFVFLVYTSSKELGSPSVVYDRLKDMVAKSRSCTEPLSHHGQACGPVDGNFRGSYLTMLSSGGAVFGLINIVGNFGTVFVDNGYWVSAIAARPSSTHKGYLLGGLVWFAVPFSLATSLGLGALALDLPISKDEADRGLVPPATAIALMGKSGSLLLLTMLFMAVTSAGSSELIAVSSLFTYDIYRTYINPRATGRQILKISRCAVLGFGCFMGILAVVLNKAGVSLGWMYLAMGVLIGSAVIPIAFMLLWSKANAFGAILGATSGCVFGIITWLTTAKTQYGRVDLDSTGKNGPMLAGNLVAILTGGLIHAVCSLVRPQNYDWSTTREIKVVEAYASGDEDVDVPAEELREEKLRRAKAWIVKWGLVFTILIVVIWPVLSLPARVFSRGYFWFWAIVAIAWGTIGSIVIIGLPLVESWDTIKSVCMGMFTNDRVMKKLDDLNHRLRALTMAVPEAEKIYLLELEKTKKNDEEG
What is the function of this protein?
High-affinity urea-proton symporter involved in the active transport of urea across the plasma membrane into root cells.  May play an important role in urea uptake by plant cells at low external urea concentrations.
What are the official names of this protein?
Urea-proton symporter DUR3, AtDUR3, High-affinity urea active transporter DUR3.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYC1_YEAST
Sequence: MDLPKDKSDRTHQRINLNNSGTDRTNDLYLHIVQTFGCIETTATENATKLLMLGDVEVEISASSVSIEWTQKSMISQTIADSIVIMIIGLCASDKNVLSESELKERNHNVWKIQELQNLFREQFGDSFSIDEGIGKKENVKNGSVTIGKSKATIDFSTMKLIDCNSNPLKGRVESILSIGQKLTTPLC
What is the function of this protein?
Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation, including snoRNAs and snRNAs.
What are the official names of this protein?
Protein SYC1.
Protein: DOK3_MOUSE
Sequence: MESVEPPVKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWDVRDGGLGPAGDRSTGPSRRGERRVIRLADCVSVLPADGESCPRDTGAFLITTTERSHLLAAQHRQSWVDPICQLAFPGTGECSSGSGQAESPKRGFVPMEENSIYSSWQEVTEFPVIVQRTEATSRCQLKGPYLLVLGQDDIQLRETSKPQACFSWPYRFLRKYGSDKGVFSFEAGRRCDSGEGLFAFSSPRAPDICGVVAAAIARQRERLPELAMSPPCPLPRALSLPSLEPPGELREVAPGFELPTPRKLPLTDPGPQSLPLLLSPTQEGPASGLYASVCKQTSKHTGTAEHLYENVCMLEASPGLTNGGPEAQEGPPGGRSPLGSPIYHNTEDLSWPGSAQDSNLEAQYRRLLELELDEAGSAGRSGAQAGIKAKLVTLLTRERKKGPAPCDRP
What is the function of this protein?
DOK proteins are enzymatically inert adaptor or scaffolding proteins.  They provide a docking platform for the assembly of multimolecular signaling complexes.  DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1.  May modulate ABL1 function.
What are the official names of this protein?
Docking protein 3, Downstream of tyrosine kinase 3, p62(dok)-like protein, DOK-L.
What is the protein family that this protein belongs to?
Belongs to the DOK family. Type A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BBP_PIEBR
Sequence: MQYLIVLALVAAASANVYHDGACPEVKPVDNFDWSNYHGKWWEVAKYPNSVEKYGKCGWAEYTPEGKSVKVSNYHVIHGKEYFIEGTAYPVGDSKIGKIYHKLTYGGVTKENVFNVLSTDNKNYIIGYYCKYDEDKKGHQDFVWVLSRSKVLTGEAKTAVENYLIGSPVVDSQKLVYSDFSEAACKVNN
What is the function of this protein?
This protein binds the blue pigments bilins.
What are the official names of this protein?
Bilin-binding protein, BBP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS10_SULIA
Sequence: MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRLPHGEGRKKWEKWEMRVHKRLIDIAADERVMRQLMRVRVPEDVYIEIQLI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CHO2_PODAN
Sequence: MSTTTAIDDPAGLKTTRQRNNQPQQSEIPLPSPSISDVDSDSNKGDDHRDAHVKKAYGRTPDGTGMHTLLSPSQTHDMVSQLLDPREPKNLSDYIVLGVLALHIWLAWAVPAPYNKYLLGFAFTFWRLAYNAGIGYLLTVQSKYTLLVTWARRLRAFEQPATNPRPWLYNLLKTELETKIPKDYKMDEAPIEYNTWLAFRRIVDLILMCDFVSYCLFAIVCAHTPEDEGLGMLLGRWVGGIALVGFNLWVKLDAHRVVKDYAWYWGDFFYLIEQELTFDGVFEMAPHPMYSIGYAGYYGISMMAASYDVLFISIAAHALQFVFLAFVENPHIEKTYNPPPPRLRAESEIGSQTEADALVTKELNGNSDIPQPVHNMIGSFDLFRVTDASSLIIVACFIALTVVTPTTRTYQTLAVVNAIFWRLWYSVGLGYILKKQSEKKMYTRHFLKFGESTGEAWRQWKGLYHISMILCHVSFLTACWKMYTYPEDWSYGSVLLKHVIGVSLIALQLWTSSSIYESLGEFGWFYGDFFFESPRPPTYNSIYRFLNNPERVLGAAGFWGLALITWSKAVFVMALVSQLLMLGFISFVEKPHMQKIYGQNLRKEAGLTKFVKKSLPAPVKRWQQGVDKVLDETKHFAEDFIDAALTRLSAGSSNFVKDTTALFHKPLRLSINRIDRDLAGYDPKHYKLSVEGEQLIAPDEKATRKESADARVPKDVKTKVFQYGAPIRVKWTAPANHSKKDWVGLYLVTDNRNRDFTEVPSLGRWIPTCRGQYDTTTDEGIVSYDEKVKSEGVEGPLVQGEMVFEGDKLWWTQGVYEFRYHHHGKHNVMSISEPFEVRIPLVVKEGTELTIEEAENALLPIVRNCLDRDPEIAPETVDEPWGAHVERDGKYAERVVYAIREMFAIEFSPAVVPADGNVKKLAWRVVNGRIALAPYSMSLQSRRPPTPVADSYK
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CH10_CERSP
Sequence: MAFKPLHDRVLVRRVQSDEKTKGGLIIPDTAKEKPAEGEVVSCGEGARKDSGELIAMSVKAGDRVLFGKWSGTEVTIDGAELLIMKESDILGILS
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_BACHK
Sequence: MEFDTIAAISTALGEGAIAIVRVSGDDAVEKVNRIFKGKDLTEVPSHTIHYGHIVDLDTNQVIEEVMVSIMRAPRTFTRENIVEINCHGGLVSVNKVLQLILAQGVRLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMNVAINQMEGRLSKLIGRLRQDILETLAHVEVNIDYPEYDDVEEMTHNILIEKATHVRAEIAKILETSKQGKILREGIATAIIGRPNVGKSSLLNSLVQEKKAIVTDIAGTTRDVIEEYVNVRGVPLKLIDTAGIRETEDVVERIGVERSKEMMSQADLVLVVVNYSETLTNEDEELFRAVQGKDFIVIVNKTDLPQAIDMERVIELAAGNRVITTSLIEEQGIDELEKAIADLFFEGTIDSADVTYVSNARHIGLLTQAGKTIGDAIEAIENGVPIDMVQIDLTRTWEILGEITGDTVHESLIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_SALHS
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVLEIVSGASRGIRLLQEEEDGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPSADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFTPIVVDLREQSFTIEGLAVGVIRNGEWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: TPMT_HUMAN
Sequence: MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGKSGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKVFKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQYLLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRCLEKVDAFEERHKSWGIDCLFEKLYLLTEK
What is the function of this protein?
Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748).  TPMT activity modulates the cytotoxic effects of thiopurine prodrugs.  A natural substrate for this enzyme has yet to be identified.
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMGN2_CANLF
Sequence: MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDGNNPAENGDAKTDQAQKAEGAGDAK
What is the function of this protein?
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer.  May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).
What are the official names of this protein?
Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the HMGN family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation.
Protein: FDL31_ARATH
Sequence: MSNQGAIRRSGEDRISSLPDHLLSQILSNLPTENAVTTSILSTRWKDLWLSTPVLDIDIDAFDDATTFISFATRFLDSFKDSCLHKLQISFQMEAVDMWTIIPWIEDAVKRRIQHLEVDSRIDHMIDTLPLTVYLSESLVSLRLHLVMLHRFVFVSLPNLKVMHLEENIYSYAETMEKFISSCPVLEDLTVVRNVDEATEKVLRVSSQSLNSLKLVIDSSKCWYNDDSDDWKVVIDAPQLVYLSLKDDQSVSFVINNLCSSAKADIKVSFNVSDIWDLEESFERSNVGKFLTGLSSLRDMTISGTTLKIICHYLKHEPMPQFRNMTRLHAKFYVCDLEMLPCVLESCPNLKSLVLKLKGEMENEEISLSSSVPKCLQSSLENVEIIRPNYGSGEEMKLSKYFLENSLVLKKFKLCRDCHSEEQESLVVRELMTFQRCSSACEINVVRFQR
What are the official names of this protein?
F-box/FBD/LRR-repeat protein At5g22660.
Protein: FTRC_ORYSJ
Sequence: MMSMASTTASPFCPSPMPRGRKCTVRVQAGAAGADASDKSLEIMRKFSEQYARRSNTFFCSEKSVTAVVIKGLADHKDQLGAPLCPCRHYDDKAAEVAQGFWNCPCVPMRERKECHCMLFLTPDNDFAGQDQAITLEEIKDATSKI
What is the function of this protein?
Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
What are the official names of this protein?
Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic, FTR-C, Ferredoxin-thioredoxin reductase subunit B, FTR-B.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin thioredoxin reductase beta subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPO_NEUCR
Sequence: MLSRQALLRPARVLNTQVRTYAAAAAASSKVKPPVTLFGLDGTYATALYTAAVKTSALEPTAKAISSLGNLLAKDPKLASILETPTLSPADKSAIVAELQKSVGVSNETVKNFLATLAENNRLGLLPSVVAKFSELMSAARGEVEMVVTSAQPLDNKTLNRLESAVAKSPYVGSGKKLKVTNKVNADIIGGLVVEIGERTIDLSVSSKIAKMNKLLSEAL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity).
What are the official names of this protein?
ATP synthase subunit 5, mitochondrial, ATP synthase chain 5, Oligomycin sensitivity conferral protein, OSCP.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: KTHY_HAHCH
Sequence: MKKGLFITVEGIEGAGKTTNLNFIRSILEESGEEVVMTREPGGTPMAEEVRELLLRPREEAVSSTAELLLMFAARAQHLEQKIKPTIERGVHVLSDRFTDATYAYQGGGRGLSWAMIQDLEKLVQAGFKPDLTLLLRIDPETGMARARKRGALDRFEREKLEFYFCVQEGYMKRVAEDPERFLVVDAQQSLEEVQAAIAQGLAAKLAG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: 17KD_RICPR
Sequence: MKLLSKIMIIALAASMLQACNGQSGMNKQGTGTLLGGAGGALLGSQFGQGKGQLVGVGVGALLGAVLGGQIGASMDEQDRRLLELTSQRALESAPSGSNIEWRNPDNGNHGYVTPNKTYRNSAGQYCREYTQTVIIGGKQQKTYGNACRQPDGQWQVVN
What are the official names of this protein?
17 kDa surface antigen.
What is the protein family that this protein belongs to?
Belongs to the rickettsiale 17 kDa surface antigen family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RNFG_VIBA3
Sequence: MLNAIKKNGLVLAIFACASTGLVAVTHYLTKDQIKQQEQAQLLSVLNQVIPHDLHDNELFSSCTLVQAEELGTEQAMPAYIAKINGEPSAIAIEAIAPDGYNGAIKVIVGMKIDGTILGTRVLSHQETPGLGDKIDLRVSDWILSFAGKQVTDSNLDRWKVRKDGGDFDQFTGATITPRAVVKSVKQAVQYVNQNNQALLAQPLNCGGE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rnf electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.