PharMolix/UniProtQA huggingface dataset:
Protein: RPOZ_NITEU
Sequence: MARITVEDCLEVIPNRFDMTLAATVRARQVSVGSTPMIDSERDKPIVIALRELAQKKYGEEILNTLR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: DCUP_VIBCH
Sequence: MTELKNDRYLRALLKQPVDYTPVWMMRQAGRYLPEYRATRAQAGDFMALCKNAELASEVTLQPLRRFPLDAAILFSDILTIPDAMGLGLRFAAGEGPVFERPITCKADVDKIGIPDPEGELQYVMNAVRQIRKDLQGEVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKMMYSEPTVLHALLDKLADSVISYLNAQIKAGAQAVMVFDTWGGVLTPRDYQQFSLQYMHKIVDGLIRENEGRRVPVTLFTKNGGMWLEQIAATGCDAVGLDWTINIADAKARVGDKVALQGNMDPSILYAPAPRIREEVASILAGFGQGGTGHVFNLGHGIHLDVPPENAGVFVEAVHELSKPYHP
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3439_YERPG
Sequence: MYDNLKSLGITQPEDVDRYSLRQEANNDILKIYFRKDKGEFFAKSVKFKYPRQRKTVVSDNASHGYKEINEINPNLRYVIDELDQLCKRDQIEVDLKRKILDDLRHLESVVTNKIAEIEADLEKLTNGR
What are the official names of this protein?
UPF0325 protein YpAngola_A3439.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: EFTS_STRCO
Sequence: MANYTAADVKKLRELTGAGMMDCKKALDEAEGNVEKAVEALRIKGQKGVAKREGRSAENGAVVSIIADDNTSGVLVELKCETDFVAKGEKFQNVATAIAEHVAKAAPADLEALLASEIEPGKTVQAYVDEANANLGEKIVLDRFAQFSGGFVTAYMHRTMPDLPPQIGVLVELDKPNAEIAKGVAQHIAAFAPKYLSKEDVPAEVVESERRVAEETTRAEGKPEAALPKIVEGRLNGFFKDATLLGQPYALDNKKSVQKVLEEAGVSLKRFSRIKVGI
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNBP_RAT
Sequence: MSSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGGFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA
What is the function of this protein?
Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (By similarity).  Has a role as transactivator of the Myc promoter (By similarity).  Binds single-stranded RNA in a sequence-specific manner (PubMed:7788528).  Binds G-rich elements in target mRNA coding sequences (By similarity).  Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (By similarity).
What are the official names of this protein?
CCHC-type zinc finger nucleic acid binding protein, Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum.
Protein: SYS_BART1
Sequence: MLDIKWIRENPEKLDKALVSRGLEPQAERLIQLDFARRSHVAKVQLAQERRNAVSKEIGQALAVSDEKMAERLRSEVEELKVFLSSATAEEKQLTESLEKILSALPNIPLDDVPEGKDESDNVVIRHFGLPPTFNFTPKEHFDLGQDLKQMNFERASRLSGTRFTVLSGALARLERALGQFMLDVHVNEHGYTEVSVPLLVRDEIVYGAAQLPKFAEDLFQTTDGRWLISTAEVPLTNLVNDEILEVSDLPLRFSSLSPCFRSEAGAAGRDTRGMLRQHQFWKVEMVSITSEEQSLMELERMTECAEDILKRLGLPFRTVVLSTGDMGFAARKTYDIEVWLPGQECYREISSCSVCGDFQGRRMNARYRKEGDKKLHFVHSLNGSGTAVGRCLIAVLENYQQADGSIIVPDVLQPYMGGMRCISA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_SALRD
Sequence: MLRYLTAGESHGEAIIGVLEGAPAQLPLTPDDINEHLARRWLGYGRGGRSKIENDTVHIYSGVRFGKTLGSPISFRIDNGAYEKDKAGWPEKMAIEGEPPEDMEKVTMPRPGHADLAGKQKYEHDDMRPVIDRSSARETAMRVACCSVARRLLNEFGIEVGSHVVRIGDVGFDEPEEWADRRNALIEEGGGASALYETADESATRMIDDGMTERCVEHIDQTKKDRDSLGGVYEVVVTGVPPGLGSYVHWDRRLDGQLVQAICSIQAQKAAEVGDGFFNAHRPGSQVHDPIEPREDGAQAYPRRTNHAGGTEGGTTTGMPLVVRGYMKPIPTLIKPLDSVDTATGEPEPTRYERSDITSVPAASTVAEATVAYTVANAFLRKYGGDSVPAIRRHVEADRAAPNE
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GLPR_HAEIN
Sequence: MKQSLRHQKIIKLVEQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPSSAENSDYVDRKQFFSLQKNNIAQEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVTNNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFISQFRLDFGILGISAIDADGSLLDYDYHEVQVKRAIIESSRQTLLVADHSKFTRQAIVRLGELSDVEYLFTGDVPEGIVNYLKEQKTKLVLCNGKVR
What is the function of this protein?
Repressor of the glycerol-3-phosphate regulon.
What are the official names of this protein?
Glycerol-3-phosphate regulon repressor.
Protein: RL30_ROSCS
Sequence: MSKLKITYRKSAIGYSHDQKATIRSLGLRRLNSVVVHDDTPTIRGMIFKVRHLVSVEELPDRDAPADHPGDDMKR
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ADDA_CLOBK
Sequence: MSGTKWTDEQRQAIFTKNCNLLVAAGAGAGKTAVLVQRIIEKILDKEEPIDIDKLLVVTFTNAAAAEMRERIGDAISKGLDEDPESKVLRKQLTLLNKSNIMTIHSFCLQVIKNNFHTMEIDPNFRICDETEGILMKQEAIDELFDELYEIENEDFINLVESYASRKDTRLQEVVLELHRFAKSAPFPYTWLLNMAEGFNVGENFNFEETLWADMIMEDMKVLLYGFKNMLQQSIDVILNSEGIDYYYEPFKMDLSFINSLLEKSSFKEFRGEIIAYDFPKLPLKRNKDADKEAKERVKKLRDKVKKKIVELKNILDSYENEFIKKEFIFLYPSMKALSNLVILFDKKYEAKKRERDLIDFNDIEHLCLSILTDKNSDGHIIPSDIALNYRKKFAEVLIDEYQDSNLVQEVIMSMVSRVKGYWSFYNGQLIFNEKEINLEEPQIGLDIPNRFMVGDVKQSIYRFRQAKPEIFLDKYNEYNEEEDRKNRKVKLFKNFRSREEVINGVNYLFKQIMSKTIGELDYTEEEALKVGASYGEEVKGEPIELCLMDKKYEISEEVLKEYNVDEEEALDNIQLEGRLVAKKIQKLVGNNLEGGLKVFDKKLGEYRNLQYRDIVILMRATSNWAPVFVEELAKEGIPVFADTNSGYFDTAEIKTMISLLQIIDNPLQDIPLLSVLRSPIASFTDDELIDIRMVNKNITFYECMEIIYRLYKNEKLDSYYSFYIEDENKINKIIKDMNEKLKNKICSFIEKLKLWREKSIHIDIDEFIWFLYVETGYYGYAGALQAGEQRQANLRILFQRAKQYAKTSYKGLFNFINFINKLKFSSGDMGSAKILGENENVVRIMSIHKSKGLEFPVVILSGTGKNFNMTDLNKNILFHRDLGYGPDYVDTERRIAYPSLVKNIIKNKIRLETLSEEMRILYVALTRAREKLIITGLINNMDKTVEDWLNLSEDKNKVPEYAVMSGKTYLDWIGPALIKHKDAVSFREELKMTSELSNIVDDKSKWKIELWNKRELLKEKVEEDEVEISEKIKETLMSLEESNYKEEIYKRLSFKYKYDNASSIPTKLSVSDVKKQFILDEKENTEELFKKLELRKPMFMEEKKKISPSERGTIIHLFMQHLDLKKAENEEDIKEQINRLIEREFITYEQSKVISPYKILKFCRGELGKRILNSNNVNKEMPFSIEIPALEIYKELDKEIYKNEKLIIQGVIDCYFEEEDGLVLLDYKTDYVNDIEEIKNRYEIQIKYYEEALNRITGKNVKDKYLYLFSVDNYIKID
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: GTPS_ORIVU
Sequence: MATLSMQVSILSKEVKNVNNIGMRASKPMVARRVSTTRLRPICSASLQVEEETRRSGNYQASIWNNDYVQSFNTNQYKDEKHLKKKEELIAQVKILLNTKMEAVKQLELIEDLRNLGLTYYFQDEVKKILTSIYNDHKCFKNEQVGDLYFTSLGFRLLRLHGFDVSEEVFDFFKNEDGSDFKASLGENIKDVLQLYEASFLIREGEVILEQARVFSTKHLEKKVDEGINDEKLLAWIRHSLALPLHWRIQRLEARWFLDAYRARKDMIPLIFELGKIDFHIIQETQLEELQEVSKWWTNSNLAEKLPFVRDRIVECYFWALGLFEPHEYGYQRKMAAIIITFVTIIDDVYDVYGTLDELQLFTDAIRKWDFQSISTLPYYMQVCYLALYTYASELAYDILKDQGFNSIAYLQRSWLSLVEGFFQEAKWYYAGYTPTLAEYLENAKVSISSPTIISQVYFTLPNSTERTVVENVFGYHNILYLSGMILRLADDLGTTQFELKRGDVQKAIQCYMKDNNATEKEGAEHVKYLLREAWKEMNTAMADPECPLSEDLVDAAANLGRASQFIYLEGDGHGVQHSEIHNQMGGLIFEPYV
What is the function of this protein?
Involved in the biosynthesis of phenolic monoterpenes natural products thymol and carvacrol which have a broad range of biological activities acting as antimicrobial compounds, insecticides, antioxidants and pharmaceutical agents (PubMed:20419468, Ref. 2, PubMed:30231481, PubMed:26156773).  Monoterpene synthase which catalyzes the conversion of geranyl diphosphate (GPP) to gamma-terpinene and the minor products alpha-thujene, alpha-terpinene, myrcene, sabinene, (+)-R-limonene, alpha-pinene and alpha-phellandrene (PubMed:20419468, Ref. 2).
What are the official names of this protein?
Gamma-terpinene synthase, chloroplastic, Alpha-terpinene synthase, Terpene synthase 2, OvTPS2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PHNN_ACICJ
Sequence: MPRSGRLVLVVGPSGAGKDTVLREARRRLGHAPDIVFPRRVITRPPDPAEDHEPVSDDEFQRRAFALSWSAHGLSYGIPASIVGDLDAGRIVVVNVSRAIVADARRRFPCFVVAVTAAPAILAARLAVRRRETAAEIGARLARAAAPVEADAVVANETTPEAAGAAFLGILLRCRDLPCLP
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: LEUD_POLNA
Sequence: MQKFTVHQGLVAPMDRENVDTDAIIPKQFLKSIRKTGFGPNLFDEWRYLDAGFPGQDPASRKPNPDFVLNQARYKGASILLARKNFGCGSSREHAPWALDQFGFRAIIAPSYADIFFNNSFKNGLLPIVLPEAQVAQLFDEALAFPGYTLTIDLERQVIVKAQGEELPFDVQAFRKYCLLNGFDDIGLTLLQSDKIKAFEAQRLAGKPWLSHTVAG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: STPG1_HUMAN
Sequence: MDNSAQKNERTGKHPRRASEVQKGFTAAYPTQSSIPFKSQASVIPESEKKGFNSQAKRFPHKKNDIPGPGFYNVIHQSPVSNSVSLSKKGTCMFPSMCARLDTIISKYPAANAYTIPSDFISKRDFSNSCSSMFQLPSFMKALKFETPAPNYYNASVSCCKQRNNVCTRAGFMSKTQRGSFAFADKGPPPGHYDINESLVKQSPNTLMSCFKSKTNRGLKLTSTGPGPGYYNPSDCTKVPKKTLFPKNPILNFSAQPSPLPPKPPFPGPGQYEIVDYLGPRKHFISSASFVSNTSRWTAAPPQPGLPGPATYKPELPGKQSFLYNEDKKWIPVL
What is the function of this protein?
May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.
What are the official names of this protein?
O(6)-methylguanine-induced apoptosis 2, MAPO2, Sperm-tail PG-rich repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the STPG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACEK_SALCH
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWETLLMRILSDLPLRLPWQNKSRDIRYIIAHLTETLGEDALPRCHVQVANELFYRNKAAWLVGKLTTPDGTLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRVFKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMALLRQEAPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRRQRFSVRYGAISSTANSS
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_NITEU
Sequence: MKVNPPLAWHPAPVSAPVDLHWWLTHRGSLTRLIQDRCEHFRVEPIFQALATACIDELEVMNLRRQTRALVREVYLRCNETPVVFAHSIVRKEHLRGAWRGLSRLGNQSLGTMLFTNPLIQRTPLAFKKLKPHHPLFERACKRLQNRPADLWARRSLFILQHQPILVTEVFLPAIRRL
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_ECO8A
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAPD1_HUMAN
Sequence: MVKLDIHTLAHHLKQERLYVNSEKQLIQRLNADVLKTAEKLYRTAWIAKQQRINLDRLIITSAEASPAECCQHAKILEDTQFVDGYKQLGFQETAYGEFLSRLRENPRLIASSLVAGEKLNQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQVGRLLQQLAMTGSEEGDPRTKSSLGKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEGLSRTVVYITYSQLITLVNFMKSVMSGDQLREDRMALDNLLANLPPAKPGKSSSLEMTPYNTPQLSPATTPANKKNRLPIATRSRSRTNMLMDLHMDHEGSSQETIQEVQPEEVLVISLGTGPQLTPGMMSENEVLNMQLSDGGQGDVPVDENKLHGKPDKTLRFSLCSDNLEGISEGPSNRSNSVSSLDLEGESVSELGAGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDVLGSDFDPNIDEDRLQEIAGAAAENMLGSLLCLPGSGSVLLDPCTGSTISETTSEAWSVEVLPSDSEAPDLKQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGISATSEDIPNKIEDLRSECSSDFGGKDSVTSPDMDEITHGAHQLTSPPSQSESLLAMFDPLSSHEGASAVVRPKVHYARPSHPPPDPPILEGAVGGNEARLPNFGSHVLTPAEMEAFKQRHSYPERLVRSRSSDIVSSVRRPMSDPSWNRRPGNEERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEKSDRNRPWWRKRFVSAMPKAPIPFRKKEKQEKDKDDLGPDRFSTLTDDPSPRLSAQAQVAEDILDKYRNAIKRTSPSDGAMANYESTGDNHDRDLSSKLLYHSDKEVMGDGESAHDSPRDEALQNISADDLPDSASQAAHPQDSAFSYRDAKKKLRLALCSADSVAFPVLTHSTRNGLPDHTDPEDNEIVCFLKVQIAEAINLQDKNLMAQLQETMRCVCRFDNRTCRKLLASIAEDYRKRAPYIAYLTRCRQGLQTTQAHLERLLQRVLRDKEVANRYFTTVCVRLLLESKEKKIREFIQDFQKLTAADDKTAQVEDFLQFLYGAMAQDVIWQNASEEQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQRLSKVVTANHRALQIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSFYASCLSGEESYWWMQFTAAVEFIKTIDDRK
What is the function of this protein?
Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking.  Acts as a GEF for the Ras-related protein RAB31 by exchanging bound GDP for free GTP, leading to regulate LC2A4/GLUT4 trafficking.  In the absence of insulin, it maintains RAB31 in an active state and promotes a futile cycle between LC2A4/GLUT4 storage vesicles and early endosomes, retaining LC2A4/GLUT4 inside the cells.  Upon insulin stimulation, it is translocated to the plasma membrane, releasing LC2A4/GLUT4 from intracellular storage vesicles.  Also involved in EGFR trafficking and degradation, possibly by promoting EGFR ubiquitination and subsequent degradation by the proteasome.  Has GEF activity for Rab5 and GAP activity for Ras.
What are the official names of this protein?
GTPase-activating protein and VPS9 domain-containing protein 1, GAPex-5, Rab5-activating protein 6.
What is the protein family that this protein belongs to?
Belongs to the GAPVD1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Endosome. Note=Recruited to the plasma membrane by TRIP10/CIP4 in response to insulin.
Protein: OR98B_DROME
Sequence: MLTDKFLRLQSALFRLLGLELLHEQDVGHRYPWRSICCILSVASFMPLTIAFGLQNVQNVEQLTDSLCSVLVDLLALCKIGLFLWLYKDFKFLIGQFYCVLQTETHTAVAEMIVTRESRRDQFISAMYAYCFITAGLSACLMSPLSMLISYQRTGELQPKFPFPSVYPWDNMKLSNYIISYFWNVCAALGVALPTVCVDTLFCSLSHNLCALFQIARHKMMHFEGRNTKETHENLKHVFQLYALCLNLGHFLNEYFRPLICQFVAASLHLCVLCYQLSANILQPALLFYAAFTAAVVGQVSIYCFCGSSIHSECQLFGQAIYESSWPHLLQENLQLVSSLKIAMMRSSLGCPIDGYFFEANRETLITVSKAFIKVSKKTPQVND
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity).
What are the official names of this protein?
Putative odorant receptor 98b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or1a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCAP_TOSV
Sequence: MSDENYRDIALAFLDESADSGTINAWVNEFAYQGFDPKRIVQLVKERGTAKGRDWKKDVKMMIVLNLVRGNKPEAMMKKMSEKGASIVANLISVYQLKEGNPGRDTITLSRVSAAFVPWTVQALRVLSESLPVSGTTMDAIAGVTYPRAMMHPSFAGIIDLDLPNGAGATIADAHGLFMIEFSKTINPSLRTKQANEVAATFEKPNMAAMSGRFFTREDKKKLLIAVGIIDEDLVLASAVVRSAEKYRAKVGK
What is the function of this protein?
Encapsidates the genomic RNA, protecting it from nucleases (PubMed:24688060, PubMed:28777080).  Displays high affinity for single-stranded nucleic acid (PubMed:23129612).  The encapsidated genomic RNA is termed the nucleocapsid (NC) or ribonucleoprotein (PubMed:24688060, PubMed:28777080).  The ribonucleoprotein has a non-helical structure (By similarity).  Serves as template for viral transcription and replication.  After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the phlebovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus.
Protein: RL18_CITK8
Sequence: MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ATPF_THEVB
Sequence: MSVMDALFLLATEEVGHFGINTNLLETNVINLAILIGVLVYFGRGVLGKTLGDRQKQIATAIAEAEERQKVAAARLAEAQQKLTQAKQEAQRIREDALTRAKAVKEEIIAQAKREIERLQETASQDTSAATERAIAEIRERIAAMALAEAENQLKARLSQNPDLQRTLIDRSIALLGGK
What is the function of this protein?
The complex from the organism is particularly stable to disruption and remains functional after 6 hrs at 55 degrees Celsius.
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: AROD3_ARATH
Sequence: MRTLLPSHTPATVTTAARRRHVIHCAGKRSDSFSINSSSSDWQSSCAILSSKVNSQEQSESLSSNSNGSSSYHVSAVNGHNNGAGVSDLNLVPFNNNQSIQSKKPLSISDLSPAPMHGSNLRVAYQGVPGAYSEAAAGKAYPNCQAIPCDQFEVAFQAVELWIADRAVLPVENSLGGSIHRNYDLLLRHRLHIVGEVQLPVHHCLIALPGVRKEFLTRVISHPQGLAQCEHTLTKLGLNVAREAVDDTAGAAEFIAANNIRDTAAIASARAAEIYGLEILEDGIQDDASNVTRFVMLAREPIIPRTDRPFKTSIVFAHEKGTCVLFKVLSAFAFRNISLTKIESRPNHNVPIRLVDEANVGTAKHFEYMFYIDFEASMAESRAQNALSEVQEFTSFLRVLGSYPMDMTSWSPSSSSSSSSTFSL
What is the function of this protein?
Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine (PubMed:17726025).  Together with GCR1 and GPA1, required for blue light-mediated synthesis of phenylpyruvate and subsequently of phenylalanine (Phe), in etiolated seedlings (PubMed:16415218).
What are the official names of this protein?
Arogenate dehydratase 3, chloroplastic, AtADT3, Prephenate dehydratase 1, AtPDT1.
Protein: RL4_MYCMM
Sequence: MAAQNQSAQKDLEIQVKTPDGKVDGSVALPAELFDVPANIALMHQVVTAQRAAARQGTHSTKTRGDVSGGGRKPYRQKGTGRARQGSTRAPQFTGGGVVHGPKPRDYSQRTPKKMIAAALRGALSDRARNGRIHAVTELVAGQTPSTKSAKTFLATITDRKQVLVVIGRDDQTGVKSVRNLPGVHILSPDQLNTYDVLRADDVVFSVEALNAYIAANTSEEVSA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NUOH_XYLFA
Sequence: MNTWFLNVVDPLHQWFLGFGDIGVVLWTVLKILMIAIPLIVSVAFYVVWERKLIGWMHVRHGPMYVGMGLFQAFADVFKLLFKEVLYPSKAHKAIFVIAPLLTLAPSFAAWAVVPFDTKLVLSNANVGLLYLLAMTSLGVYGIILAGWASNSKYAFLGAMRSAAQVVSYEIAMGFALVGVMIAAGSLNLSQIVMAQAGSSGFFDWFLIPLFPLFIVYWVSGVAETNRSPFDVVEGESEIVAGHMVEYSGSVFALFFLAEYANMILVSFLISIFFLGGWLSPIQGWVSGQVSPLIDWVWNGGWPWLLFKVLFFASAYIWFRASFPRYRYDQIMRLGWKVFIPLTIVWIAVTALMVFSGVIQKGV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRAC_STAAN
Sequence: MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNSIAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVMELEKENKKLQNQIQKLYGDLYNKE
What is the function of this protein?
One of three proteins encoded by transposon Tn554 required for its transposition.
What are the official names of this protein?
Transposase for transposon Tn554.
Protein: MERD_SHIFL
Sequence: MSAYTVSQLAHNAGVSVHIVRDYLVRGLLRPVACTTGGYGVFDDAALQRLCFVRAAFEAGIGLDALARLCRALDAADGAQAAAQLAVVRQLVERRRAALAHLDAQLASMPAERAHEEALP
What are the official names of this protein?
HTH-type transcriptional regulator MerD, Mercuric resistance protein MerD.