PharMolix/UniProtQA huggingface dataset:
Protein: GSG1L_RAT
Sequence: MKTSRRGRALLAVALNLLALLFATTAFLTTYWCQGTQRVPKPGCGQGGGANCPNSGANATANSTAAPVAASPAGAPYSWEAGDERFQLRRFHTGIWYSCEEELGGPGEKCRSFIDLAPASEKGVLWLSVVSEVLYILLLVVGFSLMCLELLHSSSVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDPEAIKYFRERIEKGDVSEEEDFRLACRHERYPTRHQPHMGDSWPRSSAHEAAELNRQCWVLGHWV
What is the function of this protein?
As a component of the inner core of AMPAR complexes, modifies AMPA receptor (AMPAR) gating.
What are the official names of this protein?
Germ cell-specific gene 1-like protein, GSG1-like protein.
What is the protein family that this protein belongs to?
Belongs to the GSG1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Synapse.
Protein: RL2_BURM1
Sequence: MAIVKVKPTSPGRRAMVKVVNKDLHKGKPHAALLDTQSSKAGRNNNGRITTRHQGGGHKHHYRVIDFRRTKDGIPAKVERLEYDPNRSANIALVLYADGERRYIIAPKGVTVGQQLMSGSEAPIRAGNTLPIRNIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAREGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGANRWRGIRPTVRGVAMNPIDHPHGGGEGRTAAGRDPVSPWGTPTKGFRTRRNKRTTTMIVQRRHKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: DAPB_ALIB4
Sequence: MVKIGILGSTGRVGSLLIDDLQNDKDAKLSAVHVTSKLLKTLPQDTIVTNDIKVLFDSCDVIIDFSKPSGTEALLTEVIENGAKKPLVIATTGLNKHQQNLLLEASKLVPILYATNMSLGVAVLNKLVTLASKTLRDFDIEIVEQHHRHKIDAPSGTALTLAEHAASARDLNLDDVRISGRDGNIGARTKDEIAVMALRGGDIVGRHTVGLYNDGEFLELNHTATARNTFSKGAIKVAKWIVGKDAKLYSINDALGL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGLU3_HUMAN
Sequence: MPFKAFDTFKEKILKPGKEGVKNAVGDSLGILQRKIDGTTEEEDNIELNEEGRPVQTSRPSPPLCDCHCCGLPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIMTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWSSVFYIYGMFGIIWYMFWLLQAYECPAAHPTISNEEKTYIETSIGEGANVVSLSKFSTPWKRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRQILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTRHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQEWADPENLSEEKCGIIDQDELAEEIELNHESFASPKKKMSYGATSQNCEVQKKEWKGQRGATLDEEELTSYQNEERNFSTIS
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, sodium and phosphate (PubMed:33440152, PubMed:12151341).  At the synaptic vesicle membrane, mainly functions as an uniporter that mediates the uptake of L-glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:12151341).  The L-glutamate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane (PubMed:12151341).  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification (By similarity).  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation (Probable).  The symporter activity is electrogenic (PubMed:33440152).  Moreover, operates synergistically with SLC18A3/VACHT under a constant H(+) gradient, thereby allowing striatal vesicular acetylcholine uptake (By similarity).
What are the official names of this protein?
Vesicular glutamate transporter 3, VGluT3, Solute carrier family 17 member 8.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: VAC8_YEAST
Sequence: MGSCCSCLKDSSDEASVSPIADNEREAVTLLLGYLEDKDQLDFYSGGPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQVSREVLEPILILLQSQDPQIQVAACAALGNLAVNNENKLLIVEMGGLEPLINQMMGDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSKHIRVQRNATGALLNMTHSEENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLAQTEPRLVSKLVSLMDSPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRLLDYKDSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDSPVSVQSEISACFAILALADVSKLDLLEANILDALIPMTFSQNQEVSGNAAAALANLCSRVNNYTKIIEAWDRPNEGIRGFLIRFLKSDYATFEHIALWTILQLLESHNDKVEDLVKNDDDIINGVRKMADVTFERLQRSGIDVKNPGSNNNPSSNDNNSNNNDTGSEHQPVEDASLELYNITQQILQFLH
What is the function of this protein?
Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
What are the official names of this protein?
Vacuolar protein 8.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
Protein: RIBB_BORPE
Sequence: MSNVVPTPVFPLFAQPFATRLERALQHLRIGRPVILMDDFDRENEADLIVAADKLTVPVMAQLIRDGSGIVCLCLPGETLDRLELPPMVDSNRSRYSTAFTVSIEAREGVTTGVSAVDRVTTIRAAIAPGARSGDVVSPGHVFPLRAQPGGVLTRRGHTEGSVDLAALAGLRPAGVLCELMNADGTMMRGASLERYAAKEGLVALAIDELAAHLQARGATGAPAELAVAA
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RL7_PORG3
Sequence: MADIKAIAEQLVNLTVKEVSELATILKEEYGIEPAAAAVAVAAAPGAAGAAAEEEKTSFDVVLKSAGAAKLQVVKAVKEQCGLGLKEAKDLVDAAPSTVKEGVDKATAEALKKALEEAGAEVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: AMPU1_AMPCP
Sequence: MKAIMVLFYVMMLTIIASVSMVNGSPGKDDYVNPKEQLGYDILEKLRQKP
What is the function of this protein?
Amphipathic peptide which probably adopts an alpha-helical structure.  When injected in subesophageal ganglia of cockroach P. americana, a natural host for larvae of A. compressa, dampens the escape response for about 1 hour which may contribute to early stages of hypokinesia.  Has no antimicrobial activity against E. coli DH5alpha or B. thuringiensis.  Is not cytotoxic in vitro.
What are the official names of this protein?
Ampulexin 1, Axn1.
What are the subcellular locations of this protein?
Secreted.
Protein: GLGC1_VIBPA
Sequence: MAGVLGMILAGGEGSRLRPLTESRSKPSVPFGGSYRLIDFALNNFVNADLMRIYVLTQFKSQSLFHHLKKGWNINGITDRFIDPIPAQMRTGKRWYEGTADAIYQNLRFMELEEPDQVCIFGSDHIYKMDIKQMLNFHTEKKASLTVSALRMPLKEASQFGVIEVDAEGRMIGFEEKPANPKSIPGEPDFALVSMGNYVFEAQVLFSELVEDADNEASSHDFGKDIIPKMFPRGDVFVYDFSTNRISGEKEEVYWRDVGTIDAYWQAHMDLLEKDAPFSLYNRKWPLHTYYPPLPPATFTDSDNGRVQIIDSLVCNGSYVRGSRIEKSVLGFRSNIASACDISECILLGDVKIGEGCVLRRVIVDKDADIAPGTQIGVNLQEDKKHFHVSEEGIVVIPKGARVGY
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase 1, ADP-glucose pyrophosphorylase 1, ADPGlc PPase 1, ADP-glucose synthase 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: SYC_HYDCU
Sequence: MALKIYNTETRQKETFTPIQPNKVGLYVCGVTVYDYCHVGHARVMVVFDTVVRHLRSLGYDVTYVRNITDIDDKIIQRALENKESIQSLTSRFIDAMHEDEKALNVLRPDMEPKATEYMDEIETMISTLIEKDFAYPAENGDVYFHVKADDDYGRLSGKNIEELDSGSRVEINSVKKDPLDFVLWKASKENEPAWQSPWGDGRPGWHIECSAMSTKCLGNHFDIHGGGLDLSFPHHENEIAQSECATGEHYVNSWMHCGFVRIDDEKMSKSLGNFFTIREVLKQYHPEVIRYFLLASHYRSPVNYSEENLDVAKASVGRLYSALELVPADQAEPAESKLEAEFMAAMNDDFNTPQAMAVLFELAKEVNKQKSPGLAALLKKLANQIGLLEQTAESFFKSQPSDSDLTDEMIEALIVERAEARKAKDFSRSDEIRDELLAQGIELLDSAEGTSWRKI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_DICNV
Sequence: MQHTLKKSDFFYELPEHLIARYPLQNRSDSRLLVAAVESAQKVHISNKQMIDFIDFLKPEDLLVINNTRVVPARMFGHKISGGKVEVFIERLLSEQRVKAHIRASKAPLLGSQIVIGAQKVTIEDKKDGIYTVFSEMPWTKLMAQQGKMPIPPYLARDAEALDSERYQTVYAQIAGAVAAPTAGLHFDQKLLERIAAKGVKRAAITLHVGAGTFQPVRVENLNEHVMHQEWFSLSQEVVDAVAACRAQNGRVIAIGTTALRALESAAIGSGKVGVFQGDTDLFITPGYEFQVVDALFTNFHLPESTLLMLVSAFAGVNNIRRIYQHAITEQYRFFSYGDAMFLPHRLPALETLL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAT2_CANGA
Sequence: MSVQLDPSALQKMAEVAAAAEQQSNEPMTVDEEYELWKSNVPMLYDFVSETRLTWPTLTVEWLPQKNLVAARTRQQLILGTHTSGEEQNYLKIGAVDLPVEVTENSKKDREIDEEDEDMVLSNVKIVKKFPHDGEITRARYMPQDDNIIATINGEGKIFIYDRSKNGVEALLSTLEYHTENGYGLAFNANEKYSLLSGSDDSNIALWDISNFEKNIKPTITFEDAHTDIINDVKWHSSEAHIFGSVSEDSTMKLFDKRSSQIIHNINTKKPYNTLAFSPFSSNLFAAAGTDNLVYLYDIRDVSNPLYAMTGHEDAVTAIEFDPNNDGILYSSGSDRRTIVWDLQEIGAEQTQDEIEDGPPEVLMIHAGHKTSINDIAVNPNINWLVASAEEDNIVQIWKCSSNIPRIGGEPEVDLSILD
What is the function of this protein?
Regulatory subunit of the histone acetylase B (HAT-B) complex.  The complex acetylates Lys-12 of histone H4 which is required for telomeric silencing.
What are the official names of this protein?
Histone acetyltransferase type B subunit 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL6_MICLC
Sequence: MSRIGRLPITIPAGVDVTIDGDRVSVKGPKGQLEHSLPTPITATLEEGQVTVARPDDERESRSLHGLTRTLISNMVEGVTNGFSKQLEVVGTGYRVQAKGQDLEFALGYSHPVPVKAPQGITFTVEGNRVTVAGIDKQQVGETAANIRKLRRPDPYKGKGVRYAGEQIRRKAGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MATK_SPIPO
Sequence: MEEFKGYLQKGGFKQQHFLYPLLFQEYIYVLAHDHGLNVNASTFNEPSEISGYDNKSSLLLVKRLITRIYQQNSLIHSVNDSNQNIFVGHNKNFYYQMISEGFAIVVEIPFSLRLVSSFKEKKEIPKSQNLRSIHSIFPFLEDKFAHLNYVSDILIPYPVHLEILVQILQCWIQDVPSLHLLRFLFHQYHNGNNCITPKKSSYGFSKDNPRLYRFLYNSYVVEYESIFVFLRKSSSYLRSTSFGTLLERTYFYGKMKNIGVTHSNNFQKTLWLFKDPFMHYVRYQGKSIMASKGTHLLMKKWKSYFVNLWQCHFHFWSQPSRIHINQFSHFSFYFLGYLSSVPRNRSSVTTQMLENSFLIETVTKKFETMVSIIPMIGSLSKAKFCNLSGNPISKPVWADLSDLDIIDRFGRICRNLSHYYSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRAFLQRLGSEFLEEFFMEEEKVLSLILPRTSYPLHKLYRAPIWYLDIIRINDLVNNL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MATK_GOMPU
Sequence: MEEFQGHRELDRSWQHNFLYPLIFQEYIYTXAYDNGLNKLILLENGVDQKYSLLTVKRLITRLYQQNHLILSANDSNQNEIFGHKHKKNLYLQMITEGFAVIVEIPFSLLLISSLDGKEKKIVKSPNLQSIHSIFPFLEDKFLYLNYVLDILIPYPAHLEILVQTLRYWLKDASSLHLLRFFFYECRNWTSRITSKESISFLKTRNRRLFLFLYNFYVCEYESFFVILRNQSSYLRSTSFGALLERIHFYGKFKYLVKVKACAVILCFFKEPFPHYVRYQGKALLASKGTSLLMHKWKYYFISFWQCYFSVWSQPRRIYINQLSNYSLDFMGFLSSVRFNSSVIRSQMLENSFLLENIRNKFDPIVPISPLVGSLAKSKFCNVLGHPIGKSVWTDLSDSDIIDRFGRICRNLSHYYSGSSRKKNLYRIKYILRLSCARTLSRKHKSTVRAFLKRLGSEFLEEFFTEEEKVLSLILPRDSSTSGGLYKGRVWYLDIICIHNLVNDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS21_SYMTH
Sequence: MSEVKIGKNESLDSALRRFKRQLQRAGVLAEIRKREHYEKPSVKRKKKSEAARRRKYR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: YJ51_SCHPO
Sequence: MMSNENFDNDYNLPPPNDSAEDLKIFIKRYERSVDSTLLEIDENKREALEKYIEERDRKMKYEIECNERLQGWKKLAIEREISEEQSGEVQFPRWIDEWANTKLGGIFERIFSKMDSMQNDMNSRFDAMQNEMNSRFDTVQNEMTSMKGEMAEMKVEMVEMKRETIRLNTRIDLLEQKTEARFQSIEQRFNSIDQRFNSIDRRFDSMEQRLDSMDQKMETIDARSCRSIMLTRKLENTTRSDQGYLA
What are the official names of this protein?
UPF0612 protein P20C8.01c.
What is the protein family that this protein belongs to?
Belongs to the UPF0612 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_STRPM
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: T2R16_RAT
Sequence: MVPTQVTIFSIIMYVLESLVIIVQSCTTVAVLFREWMHFQRLSPVEIILISLGISHFCLQWTSMLYNFGTYSRPVLLFWKVSVVWEFMNVLTFWLTSLLAVLYCVKVSSFSHPVFLWLRLKILKLVLWLLLGALIASCLSIIPSVVKYHIQMELLTLDHLPKNSSLILRLQMFEWYFSNPFKMIGFGVPFLVFLISIILLTVSLVQHWGQMKHYSSSSSSLRAQCTVLKSLATFFIFFTSYFLTIVVSFIGTVFDKKSWFWVCEAVIYGLVCIHFTSLMMSNPTLKKALRLQFWSPESS
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
What are the official names of this protein?
Taste receptor type 2 member 16, T2R16, T2R18, T2R3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_HELPG
Sequence: MVVAKKSLGQHFLTDESFLDRIVNALPPLNPLKLIEIGVGLGDLTLKLLDRYPLKTYEIDSNLCEKMRARLKAQKKPFQLELVEKDALFLKEEEPYFLISNLPYYIATRLVLNALKDPKCRGLLVMTQKEVALKFCTKDSQNALSVLVHTIGNATLLFDVPPSAFSPPPKVFSSVFEVIKEPLKEKALASLLQAPFFEEALQKGFETLEDFLKACFSSPRKTLSNNLKKSVSYREKLDKVLDFLALENQPTSVRASEIKDYLKLLEYLLKG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZO14_XENLA
Sequence: TGKYPFICSECGKSFMDKRYLKIHSNVHSGNTFPCTECGKSFAAKQNLKRHQKIHTGEKPHKCTECGKQFLQKNKLDRHHLSHTGVKPFSCFECGEQFTWKHLLQYHQLSHTGERPFVCSECGKGYKTKASLALHCHIH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Oocyte zinc finger protein XlCOF14.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 5NTC_DICDI
Sequence: MAENNNNNNNNNNNNVSTPPHQKPHLTTGLRTSSSGLLMDKRRQDEEKFSAEQVAMGKKSPTKLFSAYSLNDLSNPPTDEELNNYKDLPASSLPPIHKREKLRRVFVNRDIKLDRIEFFGFDMDYTLAVYNSPDFEELAYDMVLDKLIDIGYPKSIRKLKYDPNFPTRGLFLDRELGNLLKIDSFGNIIICVHGRTTLSKNRTAEFYPSMRVSSDEIARNRFYLLNTLFTLPEACLYADLVDHLERESGLRLTEEVADEQQQMNSPPLSSLGSESVRIDESNHQPEGDLSFSNLFQDVRTACDLVHNDGSLKTRVLDDLPRYIRKTPDMPVFFDRLRQNKNKVFLLTNSEFYYTNKVMSYMMNGYNPNYQSWRDYFDVIIVGADKPRFFSEGTTIREVDTETGNLRITNVKDRFEQGKVYHGGSLSLFQKLTGAKGSRVLYIGDHIFADIIKSKKTHGWRNLLVVPELQHELEVMNQQKDTTIHLMNLEFIRAEIYRGLDSESTTPPDIEVLHQHLKNTNDKLNFAYNKYFGSLFKNGSKSTFFSMQVQRYADLYTSDYLNLLNYPLFYHFCANSLPLPHESSSFSSFDTSN
What is the function of this protein?
Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates.  In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside.  Through these activities regulates the purine nucleoside/nucleotide pools within the cell.
What are the official names of this protein?
Cytosolic purine 5'-nucleotidase, Cytosolic nucleoside phosphotransferase 5'N.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PKGB_EMENI
Sequence: MSGGFYSSPFWAGYLETQRSRLPVLPEIDDGLSHCVVRFLGYNPGSMQLQGTNTYLVGTGSTRILIDTGEGAPQWAVSVTRYLEDHDISISHVLLTHWHKDHTGGVADLLAHDPSIIVYKHAPDPGQQAIANGQTFKTQGATLRAVLTPGHAVDHMCFLLEEENALFTGDNVLGHGYSVAEDLETYTASLRLMAGLKCSVGYPGHGDAILNLPQTIARYISQRVAREKKIYAILALHACSCSSRNGGSTSSIGSVSESGDSDEEDNNMKTSRPAMQGLSTAEIGGLVYGESVKNSPTFDSAVGPLLNQVLYMLLEQGKCCDHVSILVIFQKPGFFSIPVI
What is the function of this protein?
Thioesterase; part of the pkg gene cluster that mediates the biosynthesis of dihydrocitreoisocoumarin and 6,8-dihydroxy-3-(2-oxopropyl)-isocoumarin (PubMed:22510154).  The non-reducing polyketide synthase pkgA performs the condensation of one acetyl-CoA starter unit with 6 and 5 malonyl-CoA units, respectively (PubMed:22510154).  As pkgA lacks a releasing domain, the thioesterase pkgB is necessary to break the thioester bond and release dihydrocitreoisocoumarin and 6,8-dihydroxy-3-(2-oxopropyl)-isocoumarin from pkgA (PubMed:22510154).
What are the official names of this protein?
Thioesterase pkgB, Pkg biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: RL5_STAAS
Sequence: MNRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLANFGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TBC12_DICDI
Sequence: MICFDNSTAHTDSNNNNNQCDLPENYKELVTTGKVEKLILSPSSSLDRPKTLPPKSQEEVLKHQREYEEIQRKAKKTLEREAKEKEKLDAIRKEKERSLIDARKVWEEDIIPVWEKNSKKRDIKKIKDLSWRGLPPAVRGKIWRLCIGNDLRVTDELFNIFLGHANNAYNKTTSPPLKSSLSSSSKSPNINIDLRQANNSIHHSRSPMNTSTDGEDDVLDLETTNMALILQDIQDTFPSLMIFQKGGPLHSDLIDVLGAYICYRPDIGYVPGMTFLAAMFLLNMEKCDAFLSLSNHINSVCFLPFFRQDQSGIPKYLAAMDSTVEALTPPLHKHFKEIGISAKNYLVDWITTLFSKALPLDVATRIWDLVFIEGEIFIYRTALSILRYFISDLIQATYDECIDLFNKLPQRKISEDKLFEEIQSIVLDQRKFDKLLEK
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s) (By similarity).  Required for osmotic regulation by the contractile vacuole in hypo-osmotic environments.  Essential for periodic fusion of the contractile vacuole with the plasma membrane and consequent expulsion of water from the cell body.
What are the official names of this protein?
Drainin, TBC1 domain family member 12 homolog.
What are the subcellular locations of this protein?
Contractile vacuole membrane. Cytoplasm.
Protein: CAPSP_ADE05
Sequence: MRRAAMYEEGPPPSYESVVSAAPVAAALGSPFDAPLDPPFVPPRYLRPTGGRNSIRYSELAPLFDTTRVYLVDNKSTDVASLNYQNDHSNFLTTVIQNNDYSPGEASTQTINLDDRSHWGGDLKTILHTNMPNVNEFMFTNKFKARVMVSRLPTKDNQVELKYEWVEFTLPEGNYSETMTIDLMNNAIVEHYLKVGRQNGVLESDIGVKFDTRNFRLGFDPVTGLVMPGVYTNEAFHPDIILLPGCGVDFTHSRLSNLLGIRKRQPFQEGFRITYDDLEGGNIPALLDVDAYQASLKDDTEQGGGGAGGSNSSGSGAEENSNAAAAAMQPVEDMNDHAIRGDTFATRAEEKRAEAEAAAEAAAPAAQPEVEKPQKKPVIKPLTEDSKKRSYNLISNDSTFTQYRSWYLAYNYGDPQTGIRSWTLLCTPDVTCGSEQVYWSLPDMMQDPVTFRSTRQISNFPVVGAELLPVHSKSFYNDQAVYSQLIRQFTSLTHVFNRFPENQILARPPAPTITTVSENVPALTDHGTLPLRNSIGGVQRVTITDARRRTCPYVYKALGIVSPRVLSSRTF
What is the function of this protein?
Major capsid protein that self-associates to form penton base pentamers, each in the shape of a pentagon, situated at the 12 vertices of the pseudo T=25 capsid.  Involved in virus secondary attachment to host cell after initial attachment by the fiber protein.  Binds host integrin heterodimer ITGAV-ITGB5 (alphaV-beta5) thereby triggering clathrin-mediated endocytosis of virions.  Mediates initial virus attachment to CXADR-negative cells.  Binding to integrins ITGAV-ITGB5 also seems to induce macropinocytosis uptake of the virus.  As the virus enters the host cell, penton proteins are shed concomitant with virion acidification in the endosome.
What are the official names of this protein?
Penton protein, CP-P, Penton base protein, Protein III.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae penton family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Located at each vertex of the virion. Present in 60 copies per virion.
Protein: VATA_ARATH
Sequence: MPAFYGGKLTTFEDDEKESEYGYVRKVSGPVVVADGMAGAAMYELVRVGHDNLIGEIIRLEGDSATIQVYEETAGLTVNDPVLRTHKPLSVELGPGILGNIFDGIQRPLKTIARISGDVYIPRGVSVPALDKDCLWEFQPNKFVEGDTITGGDLYATVFENTLMNHLVALPPDAMGKITYIAPAGQYSLKDTVIELEFQGIKKSYTMLQSWPVRTPRPVASKLAADTPLLTGQRVLDALFPSVLGGTCAIPGAFGCGKTVISQALSKYSNSDAVVYVGCGERGNEMAEVLMDFPQLTMTLPDGREESVMKRTTLVANTSNMPVAAREASIYTGITIAEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLAARLASFYERAGKVKCLGGPERNGSVTIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLISYSKYSTALESFYEKFDPDFINIRTKAREVLQREDDLNEIVQLVGKDALAEGDKITLETAKLLREDYLAQNAFTPYDKFCPFYKSVWMMRNIIHFYNLANQAVERAAGMDGQKITYTLIKHRLGDLFYRLVSQKFEDPAEGEDTLVEKFKKLYDDLNAGFRALEDETR
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar H(+)-ATPase subunit A, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.