PharMolix/UniProtQA huggingface dataset:
Protein: ACDS_CLOAB
Sequence: MDFNLTREQELVRQMVREFAENEVKPIAAEIDETERFPMENVKKMGQYGMMGIPFSKEYGGAGGDVLSYIIAVEELSKVCGTTGVILSAHTSLCASLINEHGTEEQKQKYLVPLAKGEKIGAYGLTEPNAGTDSGAQQTVAVLEGDHYVINGSKIFITNGGVADTFVIFAMTDRTKGTKGISAFIIEKGFKGFSIGKVEQKLGIRASSTTELVFEDMIVPVENMIGKEGKGFPIAMKTLDGGRIGIAAQALGIAEGAFNEARAYMKERKQFGRSLDKFQGLAWMMADMDVAIESARYLVYKAAYLKQAGLPYTVDAARAKLHAANVAMDVTTKAVQLFGGYGYTKDYPVERMMRDAKITEIYEGTSEVQKLVISGKIFR
What are the official names of this protein?
Acyl-CoA dehydrogenase, short-chain specific, Butyryl-CoA dehydrogenase, SCAD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: PSPC_CANLF
Sequence: GIPCFPSSLKRLLIIVVVIVLVVVVIVGALLMGL
What is the function of this protein?
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
What are the official names of this protein?
Pulmonary surfactant-associated protein C, SP-C, Pulmonary surfactant-associated proteolipid SPL(Val).
What are the subcellular locations of this protein?
Secreted, extracellular space, surface film.
Protein: C3H37_ARATH
Sequence: MAHRQLYSYALQPSYAAAASTVSPAPPPPQQPLPPKTGLSSLYGSSADHYFPDTTYRFLARDGSEALSNYSGTLASSSSMYHHLPNTTASHLAYPQLLQHQEVAWPPGVEVPGAASAVEPLPPGVKRTSEALYYPTLLGAHNTIGQTEAWYTTDYFTKRPKLESTSHLPIYPQRAGEKDCTHYMQTRTCKFGESCRFDHPIWVPEGGIPDWKEAPVVPNEEYPERPGEPDCPYYIKTQRCKYGSKCKFNHPREEAAVSVETQDSLPERPSEPMCTFYMKTGKCKFGLSCKFHHPKDIQLPSSSQDIGSSVGLTSEPDATNNPHVTFTPALYHNSKGLPVRSGEVDCPFYLKTGSCKYGATCRYNHPERTAFIPQAAGVNYSLVSSNTANLNLGLVTPATSFYQTLTQPTLGVISATYPQRPGQSECDYYMKTGECKFGERCKFHHPADRLSAMTKQAPQQPNVKLSLAGYPRREGALNCPYYMKTGTCKYGATCKFDHPPPGEVMAKTTSEADAAGATNTDTTQ
What is the function of this protein?
Involved in flower development (PubMed:11595801, PubMed:12530963).  Functions in floral reproductive organ identity by binding AGAMOUS (AG) pre-mRNA and promoting its processing.  Functions in association with HUA2 and HEN4 (PubMed:12530963).
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 37, AtC3H37, ENHANCER OF AG-4 protein 1.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Nuclear with a speckled distribution pattern.
Protein: BOT4_BOTFU
Sequence: MVEYNVTSTTLEPKTGWPVVDRLLGGYTELETLNGQVVARCLVAIILCRFIAVWSYNLWFHPLARFPGPFLGRCSLLYRFIHSSRGRIHSAVADAHKKYGDIVRIAPNELSFASVESWKAIYGHPTRGNEIAPKGPFYEVFAAGFNSKCVGSERNPEKHALMRKMLNPAFSQRGLLEQEEIISGTIDKFVHVLGEKAGPGTKGLNMTKWYEMNSFDILGEMAFGESFHSLDTGIPHFWADVVLEHLYIITLLDNLRRIGWLAKLAGLLIPASLVTKNQNSNYSRQQVEKRLGIQKSRNDFVSLLVDKVRAGEVSKEEMTAHVSTITIAGGETVATTLSGLTCFLAQNPDKLERLTKEIRAAFKTFEEINAVKSQQIPYLQAVINEGLRLFPPASGGAPRVSPGFTLHDKYIPKGTEVNVSPWSITHNAKYFSDPWEFKPERWLDPNSKDIKDASRPFLLGPRDCLGRNFALMELNLVLAKLLWSYDMELVNKEINFLEQSTVHVLWWKPGLFVRWHKPQSPGFSPS
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of botrydial (PubMed:14651630, PubMed:19476353, PubMed:27529428).  Botrydial is necessary for colonization of plant tissue by the T4 strain (PubMed:19035644).  It is a strain-dependent virulence factor since highly aggressive strains like SAS56 or B05 still retain substantial virulence when botrydial synthesis is impaired, since they produce also botcinic acid (PubMed:15986930).  The first step of botrydial biosynthesis is performed by the sesquiterpene synthase BOT2 which catalyzes the cyclization of farnesyl diphosphate (FPP) to presilphiperfolan-8-beta-ol (PSP) (PubMed:19035644, PubMed:19476353).  The cytochrome P450 monooxygenase BOT4 then catalyzes the hydroxylation at C-4 to give a probotryane intermediate (PubMed:27529428, PubMed:28617493).  Acetylation of the hydroxyl at C-4 is carried out by the acetyltransferase BOT5, followed by the combined action of the P450 monooxygenases BOT3 and BOT1, to yield finally the glycol, via the regio- and stereospecific hydroxylations at C-10 and C-15 of the probotryane intermediates, respectively (PubMed:15986930, PubMed:27529428).  The cleavage of the C10-C15 bond of probotryane skeleton is an intriguing and chemically important reaction, which could be mediated by some of the monooxygenases or by a combination of them (PubMed:27529428).  It is possible that either BOT3 or BOT1 would oxidize either the 10- or the 15-hydroxy group to the hydroperoxide derivative, which would then undergo heterolytic fragmentation to give the dialdehyde botrydial (PubMed:27529428).  Finally, the dehydrogenase BOT7 might be involved in the conversion of botrydial to dihydrobotrydial (PubMed:27721016).
What are the official names of this protein?
Cytochrome P450 monooxygenase BOT4, Botrydial biosynthesis cluster protein 4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CTU2_DROMO
Sequence: MCSIGEDDFGDEGGTHAMLPSCSETGIVLRAGDCSKCGQSSQQLYKLNFRSAECSECFLKYVRHKFRAALGAAKVLPRNAEILLVIDGSSESLVLLDMVHFAQTQNTFKRLHCNARVLYVDAHCSPIKEEESPLLALNELQRRYEPFEFYVIQLNGDPQSLQLLKDYTVRQLDSILDQFNSSTSRQDYMQQKRKFLVGGVAMKLKCSHVFEPSISPSLATQLLTSVALGRGASVALDVALLDDRLMGDVKLLRPLKDLNDQEVQFYVHAKELKAFRVDDPSHYPLSGGSLQSLTRDFVANLQLNYASTVSTVFRTGDKIAPKRNSKEIMASYCALCQSLLDNNISDTLLAIEYSRAVSEVGVELKMKSSCDVLEQRVLERLNEKEELCHACRNIQAELSSGTLI
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_SHIF8
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPIYRQYHHDKLTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFASLRAYYGWMWAFPGKKLLFMGNEFAQAREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSIHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RL27_THEPX
Sequence: MKLQLFAHKKGVGSSRNGRDSESKRLGVKRADGQFVLAGNILVRQRGTKIHPGVNVGKGKDDTLFALIDGYVTFERKGRDKKQVSVYPERKVAQN
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: EX7S_GLAP5
Sequence: MAKKPTLDFETTLKELEEIVNRLETGDLPLEEALNEFETAVKLVQQGQERLQKAEQRIQILLQKNEHADLTDYP
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_HALMA
Sequence: MSAEDTPEADADAAEESEPETARAKLFGEWDITDIEYSDPSTERYITVTPIAHTMGRHADKQFKKSEISIVERLINRLMQTDENTGKKQLATSIVTEAFELVHERTDENPIQVLVSAVENSAPREETVRLKYGGISVPKAVDVAPQRRVDQALKFLAEGVYGGSFKTTTTAAEALAQQLIGAANDDVQTYAVNQKEEKERVAAAAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7, HmaS7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PFLAC_MYCAP
Sequence: MAKDKFVRTVLGDVPAESIGITDCHDHLIKNGGPEMHEHPDFLMIDVEAAKKEVQEYVDHGGKTIVTMDPPNVGRDVYRMLEIAEAFKGKANIVMSTGFHKAAFYDKYSSWLACVPTDDIVKMMVAEVEEGMDEYNYNGPVVKRSKAKAGIIKAGTGYAAIDRLELKALEVAARTSITTGCPILVHTQLGTMALEVAQHLIGFGANPRKIQLSHLNKNPDRYYYEKIIKETGVTICFDGPDRVKYYPDSLLADHIKYLVDKGLQKHITLSLDAGRILYQRNYGLTKGKETFGLSYLFERFIPLLKQVGVSQEAIDDILINNPREILAFDEPRVYDASKVSSEVVQLKKDLKLL
What is the function of this protein?
Catalyzes the hydrolysis of D-xylono-1,4-lactone-5-phosphate and L-arabino-1,4-lactone-5-phosphate.  Also able to hydrolyze carboxy 1,4-lactones.
What are the official names of this protein?
Phospho-furanose lactonase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
Protein: TRPC_BACC4
Sequence: MGTILDEIVEQKQREVAELYEIYTPVKTKRKTHSLVEALQQFTVIAEVKRASPSKGDINLHVDVRKQVGTYEKCGAGAVSVLTDGQFFKGSFHDLQTAREESNIPLLCKDFIIDKIQIDRAYEAGADIILLIVAALTKEKLKELYSYVLEKGLEVIVEVHDEQELETAIVLNPHVIGINNRNLKTFEVDLSQTEKLGKRLNEEKLLWISESGIHSKEDIIRVKRAGAKGVLVGEALMTSSSISSFFEDCKVNI
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: TBA1B_MERUN
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1B chain, Alpha-tubulin 1, Alpha-tubulin I, Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SPLC_STAAB
Sequence: MNKNIVIKSMAALAILTSVTGINAAVVDETQQIANAEKNVTQVKDTNVFPYNGVVSFKDATGFAIEKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKNISDYPGNEDISVMNVEENAVERGANGYNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNTFKQFESTGTVKSIKDNNLNFDAYIEPGNSGSPVLNLNNEVVGVVYGGIGKIGSEYNGAVYFTPQIKEFIQKHIEQ
What are the official names of this protein?
Serine protease SplC.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCNB3_CAEEL
Sequence: MMLRSQAKNVDLTSQADSRHQQKRKQAEQLDALKNPSEPAAKKQHSKGLTELRAHISGFKIDSAKRDPLGKSRTSRRDVENLPPQKSRYVDPCPHYDYDLEEAGNPDSISDYAQGIFDYYRHREVHFRVRKYLHKHPEVDVKTRAILIDWMVEIQETFELNHETLYNAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDRFSRDELLAMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEYAMVSQSRLAAAAFVLAMRMLDKNNEYEWNPVLEKYSGFTGEEVMPLVEHMNHILHFSKDKWAQLTSVRQKYSHEVFFHVASIPMLPDTLKVVDSHTYAPVPMLSYP
What is the function of this protein?
Could be involved at the G2/M (mitosis) transition (Probable).  Interacts with the CDK1 and CDK2 protein kinases (Probable).  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis (Probable).  Plays a role during oocyte meiosis II (PubMed:20599902).
What are the official names of this protein?
G2/mitotic-specific cyclin-B3.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: B2MG_MICHU
Sequence: MACSVVVALLALLSLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTFSTPKTVKWDRNI
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LDH3_LACLA
Sequence: MKINNKKVVIVGAGAVGSTYAHNLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNAAPKNIYAADYSDVSDADIVVLSANAPSATFGKNPDRLQLLENKVEMIRDITRKTMDAGFDGIFLVASNPVDVLAQVVAEVSGLPKHRVIGTGTLLETSRMRQIVAEKLQINPKSIHGYVLAEHGKSSFAAWSNVTVGAIPLTTWLKKYPNPEFPTFDEIDQEIREVGLDIFMQKGNTSYGIAASLARLTRAIFRNESVILPVSAYLTGEYGQFDLYTGSPAIIDRTGVRAVLELELTQEEQEKFKASTVLLKENFDSIKEKCTL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 3, L-LDH 3, L-lactate dehydrogenase X.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_CYCTA
Sequence: MSRRSTAEKETAKSDPIYRNRLVNMLVNRILRHGKKSLAYRILYRAMKNIQQKTEKNPLSVLRQAIRGVTPNVTVKARRVGGSTYQVPVEIRSTQGKALAIRWLLGASRKRPPGRNMAFKLSYELMDAARGNGNAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: WZYE_SALCH
Sequence: MSVMQFSGLLVVWLLSTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAACFYGVYYVTYKTRLRKRVVDVPRKPLFTMNRVETHLTWVILMGIALVSVAIFFMHNGFLLFRLHSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGLNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYHNIEFQGLAPIVRDFYVFIPTWLWPGRPSIVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFLVVFGASLLVAKLLFWLFDSAGLIHKRTTSLPQAQVEGKL
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YOQO_BACSU
Sequence: MSKTIGITGFFLSIVVQSFSANDSLSHKIATGLLFVSIAIYNFDHAKDYSKASLVVICLTFFVLALGIHKLLSFSSDLFDNVNINFGVIFILQITLIIGSVAIAISIMKFICDRLKKKPNGKEC
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YoqO.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZBT17_HUMAN
Sequence: MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSLAEPATSPGGNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQAQSAASGAEQTEKADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEEQKEQEEQEEEGAGPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGSEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGGTWPAGQVLQAGELVFRPRDGAEGQPALAETSPTAPECPPPAE
What is the function of this protein?
Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression.  Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment.  Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription.  Required for early embryonic development during gastrulation.  Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 isoform 3/ZNF509S1 (PubMed:25245946).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 17, Myc-interacting zinc finger protein 1, Miz-1, Zinc finger protein 151, Zinc finger protein 60.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTD_ARCFU
Sequence: MVVKVGVLKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFDPDVVIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKDELKEKGFGYILINADSMIGARREFLDPTEMALFNADVVKVLAATGAFRLVQEAIDKVIEDIKAGKQPELPQIVVTAEKAVEAGKFSNPYAKAKAMAAFYIAEKVADIDVKGCFIEKDPEKYIPLVASAHEMMRIAAILADQAREIEKSNDTVFRNPHAKDGKILGKTQLMAKPE
What is the function of this protein?
Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT(+).
What are the official names of this protein?
F420-dependent methylenetetrahydromethanopterin dehydrogenase, MTD, Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MTD family.
Protein: SYH_PSEA6
Sequence: MSKQIQAIRGMNDCLPEQSGLWQWAEKAIREVVASYGYQEVRTPIVESTDLFKRSIGEVTDIVEKEMYTFADRNDDSLTLRPEGTASVVRAGNEHGLLYNQQQRLWYLGPMFRHERPQKGRYRQFHQFGVEVFGLAGPDIDAEVIALSARLWKKFGISEQVTLELNSLGSNEARETYRKALVEFLLARKEHLDEDSLRRLESNPLRVLDSKNPQVQAAITDAPSLIDYLDAESKEHFHALCERLDALGIQYRVNPRLVRGLDYYNRTVFEWVTDSLGAQGTVCAGGRYDGLVEQLGGKSTQGVGFAIGMERLVLMLQASGAEEFVASPVDVYVTAMGDEVELYALQIAESLRDVMPTLRVQTHFGGGNFKKQMKRADKSAARVALVLGETEQQEEQVSIKFLREDKPQSRIARSELESTLVELFSL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_PSEAB
Sequence: MTDNDDRIKLEASWKEALREEFDKPYMKQLGEFLRQEKAAGKAIFPPGPLIFNALNTTPLENVKVVIIGQDPYHGPGQAHGLCFSVQPGVPTPPSLQNIYKELNRDLNIPIPNNGYLQRWAEQGVLLLNTSLTVEQAKAGSHANAGWQPFTDRVIEVVNERCERLVFLLWGSHAQSKQKLIDPQRHLILKSAHPSPLSAYRGFLGNGHFSRTNKFLEQNGKTPIDWSLPDL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y643_PYRHO
Sequence: MNEMSSVRLPFRDGYYDVRPTKIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSIILPRRSKRVDHEVELAVIMGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISKGFDTFAPIGPRVVDSRELDPSDLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLEPGDIIATGTPPGVGPLRHGDRIEAWIEGIGKMEFDVLAEDSILC
What are the official names of this protein?
Uncharacterized protein PH0643.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: DAPH_STRZT
Sequence: MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLGNVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVKIGDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPVSAEPVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEDALRTL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: EFTS_STRPC
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNGGRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_STRPN
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQKELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINIIEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MID1_YEAST
Sequence: MIVWQALFVVYCLFTTSIHGLFQDFNPFANKNISLKFPSLNRWEKNVMATGQQTIINSDSIYEWTPILSNITAGKKDSFVFTIDAEASGYGFAPTYEVLMFISGNICQMPMNRSDVDLTIYYSFNETVLENPNIGQSAVFQDGYIQALAISPVQSSSSNATSTYSNLYVVAELVNSTTEQPLSSSDASENWEYRLSISENDLVFQWDVRPWVEVLDTDMNSALLSTGNVTADAKVYHNYSIYDPSLYDLYVYSYEDSVQLNQNYNLSLCAVKNGPYLVSSQNTSNATVTSNSTNPLERTDLAIQKKITEYGGSVTEMFYVTGLNASTTYVAYLTKKISNGDGLSSVGGILFSHVYFTTRSTDVCSLIFGLDFCSDVAYSVPTSSFSVGNKTLMAQTYDHIAEALYANFSKALQLISCDADKDARYSPVMTCDDCAEAYRDWVCAVSIPRCTTTSSQYYIHRDKSHNRNDYLNKFIKPLDDYYEILPCIDMCYTLVRNCPSDFQFSCPNDLTTEDLLYQSYNFYMDTDYSTCNYIGNSSLMVIHPLDDT
What is the function of this protein?
Calcium-permeable, cation-selective stretch-activated channel (SAC).  Required for calcium influx and for vitality of MATa cells in a late, pheromone-induced event of the mating process requiring calcium induced signaling.  Functions together with CCH1 to ensure that adequate levels of Ca(2+) are supplied to PMR1 to sustain secretion and growth.  Required for growth in low-calcium environments.  Together with CCH1, essential for tolerance to iron stress, which leads to an increased oxidative poise, and to cold stress.
What are the official names of this protein?
Stretch-activated cation channel MID1, Mating pheromone-induced death protein 2.
What are the subcellular locations of this protein?
Cell membrane. Endoplasmic reticulum. Membrane; Single-pass type I membrane protein. Note=Trafficking to the plasma membrane is dependent on the N- glycosylation and the transporter protein SEC12.