PharMolix/UniProtQA huggingface dataset:
Protein: IOLC_CLOP1
Sequence: MRYIEFDEKRKFDIVPVGRVAIDFNPTDIHKPLSESRNFNKYLGGSPANIAVGLARLGKKVGFIGKVSDDRFGEFVVNYFKKEGIDVSEISKAKNGESLGLTFTEILSPTESSILMYRNGIADLQLDVDDIDEDYIKNTKAIVISGTALAMSPSREAALKALRLAKKNGTVVIFDVDYREYNWKNKDEIAIYYSIVGKESDIIMGSREEFDLMEGLIAKDSTDEETAKRWLDYGNKIVVIKHGKDGSTAYTRDGKAYRIKPFPVKLLKSFGGGDAYASAFIYGILEGWDMMDALEFGSASAAMLVASHSCSEDMPTVEAIKEFIKKEKEEYGEMVARS
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: TYSY_SHEPC
Sequence: MQQYLDLMKHILAEGVDKSDRTGTGTRSVFGYQMRFDLSKGFPLVTTKKCHMRSIIHELLWFLKGETNIAYLRENKVSIWDEWADDNGDLGPVYGAQWRSWPTQSGDAIDQISQVIAQIKAQPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTVLQLSREPKPLPLMTILRKPESIFDYQFEDFELTNYNPHPHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_CLOBA
Sequence: MNFDIEKLEKIKVRDGQEFFFIQTFGCQMNEEDSEKLSGMLKSQGYEETENRDEASIVIFNTCCVRENAENKVFGNLGRLKNQKEKNPNLIIALCGCMMQQKGMADEILSRFPYVDIIFGTHNAYKFPEYLHRVQVEGVQVKEIFDKETEIVEGVPIDRKSNVKAFVTIMYGCNNFCTYCVVPYVRGRERSRRPEDIENEIKELVSNGYKEITLLGQNVNSYGKGLEEEITFAQLLRRINEIDGLERLRFMTSHPKDLTLDVVYAIRDCDKLCEQIHLPVQSGSNEILQKMNRHYNKEQYLELAKKIREEIPDVTFSTDIIVGFPGETEEDFEETINLVKEVRYDAAFTFIYSRRNHTPADKMEDQIPDDVKHDRFNRLVAAVNEGIVVGNKAAEGKIYEVLVEGTSKNNENKLTGRTRNAKLVNFDGCKEMIGKLVKVKIIEAKSFSLVGEVVEQ
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_XANAC
Sequence: MKLCDFEVGLDQPLFLIAGPCVIESMQLQLDVAGKLKEITGKLGVNFIFKSSFDKANRTSGTSFRGPGLEEGLKVLDAVKKQIGVPVLTDVHEYTPMNEVAAVVDVLQTPAFLVRQTDFIKNVCAAGKPVNIKKGQFLAPWDMKPVVDKAKSTGNEQIMVCERGASFGYNNLVSDMRSLSVMRDTGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLARAAVAVGISGLFAETHPDPSKALSDGPNAWPLDRMEELLETLMELDTVTKKHGFARFA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKB14_PONAB
Sequence: MRLFLWNAVLTLFVTSLIGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISAREFTYKHDEL
What is the function of this protein?
PPIase which accelerates the folding of proteins during protein synthesis.  Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen.  May also target type VI and type X collagens.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP14, PPIase FKBP14, FK506-binding protein 14, FKBP-14, Rotamase.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: LHA2_RHOCA
Sequence: MNNAKIWTVVKPSTGIPLILGAVAVAALIVHAGLLTNTTWFANYWNGNPMATVVAVAPAQ
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800/850 alpha chain, Antenna pigment protein alpha chain, LH-2.
What is the protein family that this protein belongs to?
Belongs to the antenna complex alpha subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: CINAL_PSELT
Sequence: MKTASIITVGSEIIEGIILNTNEKYICYKLTEAGLKVIRTISVDDDIESIKNAVNYSLNDSDVIVLSGGLGPTEDDKTREAIAESLKLKIALNEELKKAIEKRISKYHRYVPSNIAKQAMVIENAKILENHVGSAPGQLVFHKGKILVLLPGPPQELEPMLNNALNEIKPQPDLSTLSMLFFSIPEAELDEIITSIVHDTSVKIATQASYFDGVRVRLSAPKAKAEELTKLSKKIIELTGEKFIGYGNITLEEAVIKLLKKKHQTLSIAESCTGGMISSRLVNIPGASEVFLGAIVAYNNSVKRNILNVSNKILEKYGAVSQQCVAEMAEGVRKIMKSDLALAVSGIAGPTGGSEKKPVGTVYFCIAGESIKDIQRLFYPQQRNVFRSRVSAYGLYLILKCLSNML
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: K1C19_MESAU
Sequence: FGSGGVFRITMQNLNDRLASYLDKVRALEQANGELEVKIRDWYQKIVLQIDNARTKFETEQALRVLDELTLARKNHEEEISALRADTERQNQEYQQLMDIKLEQEIATYR
What is the function of this protein?
Involved in the organization of myofibers.  Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity).
What are the official names of this protein?
Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: ILVC_XANAC
Sequence: MSNHTQPKIAIIGYGSQGRAHALNLRDSGFDVTVGLRPGGPTEAKAQADGFTVVAPSEAVKSADLVAILTPDMVQKKLYEEVIAPNMKQGACLLFAHGLNVHFDMITPRADLDVVLVAPKGPGALVRREYEIGRGVPCIYAVYQDTSGKAEQFALTYAGGLGGARANIIKTTFKEETETDLFGEQAVLCGGASSLVQAGFEVLVEAGYQPEIAYYEVLHELKLIVDLFYEGGITRMLEFVSETAQYGDYVSGPRVIDAGTKARMKDVLTDIQNGTFTKNWVAEYDAGLPNYNKFKQADLEHPIEEVGKKLRAKMVWLNGQQQAAAAPANQQAA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PKG3_ADE12
Sequence: MHPVLRQMRPQPRATTASAAVALSGSGEQEEPQCPTLELEEGEGIARLGAHSPERHPRVQLARDSRVAFVPRQNMFRDNSGEEAEEMRDCRFRAGRELRRGFNRERLLREEDFEPDEHSGISSARAHVSAANLVTAYEQTVTEERNFQKSFNNHVRTLIAREEVAIGLMHLWDFVEAYVHNPASKPLTAQLFLIVQHSRDNETFRDAMLNIAEPQGRWLLDLINILQSIVVQERSLSLADKVAAINYSMLSLGKFYARKIYKSPYVPIDKEVKIDSFYMRMALKVLTLSDDLGVYRNDRIHKAVSASRRRELSDKELMHSLQRALTGAGTEDESFFDMGADLRWQPSARALEAAGVASADVTGDDDDEDQYED
What is the function of this protein?
Involved in viral genome packaging through its interaction with packaging proteins 1 and 2.  After proteolytic cleavage by adenovirus protease, L1 52/55k protein is removed from the capsid during viral maturation.
What are the official names of this protein?
Packaging protein 3, L1-52/55 kDa protein, Packaging protein 52K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae packaging protein 3 family.
What are the subcellular locations of this protein?
Host nucleus. Note=Nuclear protein present in empty capsids and assembly intermediates.
Protein: GATZ_SALEP
Sequence: MKEIISRHKAGEQIGICSVCSAHPLVIESALRFDLNSGNKVLIEATSNQVNQFGGYTGMKPADFRDFVYGIAQEVGFPRERLILGGDHLGPNCWQNEPADTAMEKSVELIKAYVAAGFSKIHLDASMSCADDPTPLDPMVVAKRAALLCQAAETTATDEQKRHLTYVIGTEVPVPGGEASAINAVHVTREQDAARTLQTHQAAFRALGLDEALNRVIAIVVQPGVEFDHTQIIHYQPQAAQALSAWIKETPMVYEAHSTDYQTRQAYRALVRDHYAILKVGPALTFALREAIFALAQMENELISPEQRSRVLEVIDEVMLNEPGYWKKYYRPTWSQAMVDIHFSLSDRIRYYWPHPRIRQSVEKLIANLNNVTLPLGLISQFMPVQFERLSEGVLTPTPHNLIIDKIQDVLRAYRFGCTPDVA
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: RABP1_CHICK
Sequence: MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKIGESFEEETVDGRKCRSLATWENENKIYCKQTLIEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE
What is the function of this protein?
Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.
What are the official names of this protein?
Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I, CRABP-I.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSDH_RAT
Sequence: MATCFLLRNFCAARPALRPPGRLLREPAGAQRRSYVGGPADLHADLLRGDSFVGGRWLPTPATFPVYDPASGAKLGTVADCGVPEARAAVRAAYDAFSSWKEISVKERSSLLRKWYDLMIQNKDELAKIITAESGKPLKEAQGEILYSAFFLEWFSEEARRVYGDIIYTSAKDKRGLVLKQPVGVASIITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPYSALALAQLANQAGIPPGVYNVIPCSRTKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRGIHDSFVTKFAEAMKKSLRVGNGFEEGTTQGPLINEKAVEKVEKHVNDAVAKGATVVTGGKRHQSGGNFFEPTLLSNVTRDMLCITEETFGPVAPVIKFDKEEEAVAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLEVKYVCYGGL
What is the function of this protein?
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase, mitochondrial, SSADH, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NUOD_BURMA
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVLAIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPEAMPQYKASKIRNERALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGLTGPMIRGSGIAWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCIEWLRKNPGPVITDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYQ_ECO24
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_LEPIN
Sequence: MENIIVTQVKSSIGVKKEHKLTLHALGLRRTGQQRKHKISPQLQGMLNSVRHLIKVEKA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ISPE_BACCN
Sequence: MKLLVKAPAKINLSLDVLGKRQDGYHEVKMIMTTIDLADRLELTELTEDRIEIVSHNRYVPDDQRNLAYQAAKLLKEKYQVKQGVSIAIEKTIPVAAGLAGGSSDAAATLRGLNKIWNLGLTMDELAELGAEIGSDVSFCVYGGTAIATGRGEKIEHIKTPPSCWVILAKPHIGVSTADVYGNLKLNRVTHPDVDQMAEAINRGDYQGICNAVGNVLEDVTFAMHPEVARIKTRMKRFGADAVLMSGSGPTVFGLVHHDSRMHRIYNGLKGFCEQVYAVRLLGERETLE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ACAP2_RAT
Sequence: MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCAANKQFMNGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEAANILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDSPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGSESKEKLLKGESALQRVQCIPGNTSCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEAKLEKMGVKKPQPGQRQEKEAYIRAKYVERKFVDKYSTLLSPSEQEKRIISKSCEDQRLSHTRVSVHTPVKSNDSGIQQCSDDGRESLPSTVSANSLYEPEGERQESSVFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSDENQATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
What are the official names of this protein?
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, Centaurin-beta-2, Cnt-b2.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein.
Protein: MUKB_HAEDU
Sequence: MMNTNELFDQTAVNSSQDKPLNPPFAVAQPANIARGKFRSLTLINWNGFFARTFDFDELVTTLSGGNGAGKSTTMAGFVTALIPDLTLLNFRNTTEAGSTSSSRDKGLYGKLKAGVCYAVLETVNSRAQRIITGVRLQQIAGRDKKVDIRPFSLQNVPMADSVISLFTEQVANKARVLSLNDLKEKFEETAVTFKPYHSITDYHSFMFDLGILPKRLRSSSDRNKFYKLIEASLYGGISSVITKSLRDYLLPENSGVRQAFQDMEAALRENRMTLEAIKVTQSDRDMFKHLITEATQYVSADYMRNANERRGNVVSALAQRRTWYDTKAKLLVEEQRLIEFSREVADINLTEQSLESEYNVANDHLNLVMNALRHQEKIIRYQDEVDALNEKLEQQQIALEEVSEQVEDAQAHTDEIDDRVDGLRSQIADYQQALDAQQTRALQYQQAITALQKAQQLCALPHLDLDNLKDYQTEFEAQAQDITDHVFELEQRLSISDMTKTQFEKAYQLVCKVSGEIDRSQAWSEATQLLATFPDQKMQAAQAVALRQKLADLEQRLHQQQKVQRLIAEFNQQAAKKLTDFTALENHFEQQQIKLEDLEAELANVIELRSVHRQQQEQLTQQYNQLAKTAPAWHTARSVLTRLEEQCAEQFENSQAIMHCMQEMLRKEREATLERDELARTEAALASQISQLSQADGAEDIRLNQLAERLGGVLLSELYDDVSLQDAPYFSALYGEARHAIVVRDLTSVKAQLEKLTDCPNDLYLIEGDPTAFDDTVFSAEELYDSVIVKVSNRQWRYSKFPEVPLFGRAAREKHLITLKTERDDIAEQHAESAFNVQKYQRLHQHLSQFVGTHLNIAFQPDPEMLMQEIALERQEIEGQLNQAVENEHYLRQQADHLKAELQMLNKILPLANTLADETVMERFEECREQLQSAEENELFVRQFGQYLTQLAPIATSLQTDPSKFEQLEHDYQQAKSTQRILQQKVFALSDVMQRRLHFNYSEENQCEGSALTEQLRTDLALAQQEREQARQRLRQAQAQFTQYNQVLISLRSAYDAKYQMLQELMQEIDDLGVRGDSAAEECARLRRDELQQQLSQQRARKGYLDKQLGIIEAEIDNLNRLLRKTERDYQTQRELVVQAKASWCLVQKLSRNSDVEKRLNRRELAYQSAEELRSISDKALGALRTAVADNEYLRDSLRASEDSRKPENKVAFFIAVYQHLRERIRQDIIRTDDPIDAIEQMEIELSRLINELTSREKKLAISAESVANILRKTIQREQNRILQLNQGLQNIAFGQVKGVRLVVNIRDTHSILLNALSDQHEQHKDLFESQKLSFSEALAMLYKRVNPHIELGQRMPQTIGEELLDYRNYLDLEVETLRGADGWMRAESSALSTGEAIGTGMSILLMVVQSWEEESRRMRAKDILPCRLLFLDEAARLDAMSINTLFELCERLDMQLLIAAPENISPEHGTTYKLVRKILANQEYVHVVGLKGFGQQMNKST
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: THIKA_CANTR
Sequence: MDRLNQLSGQLKPNAKQSILQKNPDDVVIVAAYRTAIGKGFKGSFRSVRSEFILTEFLKEFIKKTNIDPSLIEDVAIGNVLNQAAGATEHRGACLAAGIPYTAAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGAESMSTNYRDPRVAPRIDPHLADDAQMEKCLIPMGITNENVANQFNISRERQDEFAAKSYNKAAKAVAAGAFKSEILPIRSIIRNSDGTEKEIIVDTDEGPREGVTAESLGKLRPAFDGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIIGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVDDIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKPGQIGLTSMCIGSGMGSASILVRE
What are the official names of this protein?
3-ketoacyl-CoA thiolase A, peroxisomal, Acetyl-CoA acyltransferase A, Beta-ketothiolase A, Peroxisomal 3-oxoacyl-CoA thiolase A, Thiolase IA.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ALFL4_ORYSJ
Sequence: MDGGYGSVTIVHDARSPEDVFQDFCGRRSGIVKALTIEVEKFYKQCDPEKENLCLYGLPNGTWAVTLPADEVPPELPEPALGINFARDGMQEKDWLSLIAVHSDSWLLSVAFYFGARFGFDKKARERLFMMTSSLPTVFEVVSGGVNTQSKTANGSSKNKSGSKPPKRPNSDSKPQKQVQAKYEEENGGRGNGGDEDQAETICGACGEAYANGEFWICCDICETWFHGKCVRITPAKAEHIKHYKCPGCSNKRTRE
What is the function of this protein?
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
What are the official names of this protein?
PHD finger protein ALFIN-LIKE 4.
What is the protein family that this protein belongs to?
Belongs to the Alfin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VP1_POVMK
Sequence: MAPTVKKRTSQNQGLSPQKSQNSVVVGGIQVLDVRTGPDSITQIEAFLNPRMGKPVDSDFYGFSDNITVSADYTQDMPRIKELPCYSMAKISLPMLNEDMTCDTILMWEAISCKTEVVGVSSLTNCHSAVKRLYDNEGAGFPVQGLNFHFFSVGGEALDLQWLWKNYRCNYPAGVAALQAAPKAAQVLDPKLKAKLTADGKFPIEAWSPDPAKNENTRYFGTYTGGLQTPPVLQITNTTTTILLNENGVGPLCKGDGLYLASADIVGFRTQQNNKMHLRGLPRYFSIHLRKGCANPYPVSSLLNTFSSEMMPLNSWMLQVEEVRIYDGVERLPGDPDMIRYRIIWPGRLLSLIFPAMRHKHLYFFVMQAFIVL
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins.  Interacts with terminal alpha(2,3)-linked sialic acids on the cell surface to provide virion attachment to target cell.  This attachment induces virion internalization predominantly through caveolin-mediated endocytosis.  Once attached, the virion is internalized by caveolin-mediated endocytosis and traffics to the endoplasmic reticulum.  Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.  Next, the virion uses the endoplasmic reticulum-associated degradation machinery to probably translocate in the cytosol before reaching the nucleus.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2/Vp3 nuclear localization signal.  In late phase of infection, neo-synthesized VP1 encapsulates replicated genomic DNA in the nucleus, and participates in rearranging nucleosomes around the viral DNA.
What are the official names of this protein?
Major capsid protein VP1, Major structural protein VP1.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses coat protein VP1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: AROQ_PSE14
Sequence: MATILVLHGPNLNLLGTREPGVYGTITLPQINQDLEQRARDAGHHLMYLQSNAEYELIDRIHAARGEGVDFILINPAAFTHTSVAIRDALMGVSIPFIEVHLSNVHKREPFRHHSYFSDVAVGVICGLGASGYRLALEAALEQLAASAKP
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: CTF1B_FUSVN
Sequence: MNAETPEGSAAPPSPASTSAKTVTDKTNKKRASPSGDSEQPTKVTKRRAARACVSCRARKVRCDVVEGAPCGNCRWDNVECVVQESRRRKKNLLTASTAGQPVSTEAQLRCKTAASNPMGMSTADLRRPSSGSAISTSSIDGPSSFLSNSGLDNHVPHMIYQRSGYRHDPVLLNKLHSNDGNPQRPVWSNNLMTTPSVFDSLRTFRFISSLEEQDSTAQLPAFLRPLPTKIAAEDVKYLQIKGALSVPTLPLQNALLQAYVEYVHPYMPLMDLNSFLGIINTRDGQNGQTSLFLYQAVMFAASAFVDMKYLREGGYTTRKAARKSFFQKTRLLYDFDYESDRLVLVQALLLMTYWYETPDDQKDTWHWMGVAISLAHTIGLHRNPGSTSMAPAKQKLWKRIWWSCFMRDRLIALGMRRPTRIKDEDFDVPMLEESDFEIEVLADDNTVIPASCTLVRNLDMQRELAIMCISKAQLCVCISHMLKAQYSVLIRDKMKPENTTNSTMMLFPNKQLDNVEGVTEVDHELMAWAESLPTCCQYRTLTPLDVKDGRSTIAVQRTLLHMVYYTTISALHRPQFLPSSPLQAPTTSRQVQDMSRLRVRDAAMHITRMATELHQCRLERFLPTTGVTVILPAMIIHLLEMKNPAPQARERATRGFRQCMRVMEKLREVYAAADYATGFLDAALRKAAIDINASVGPSTLAMMKRVPVEFSAQTPPPENAPYMTAAESLFNERPKEHRPQPTPTMMPPNTVNAAALELSTNSPPQTELEESPAGLTPSVSAASEEIQLDVGNMDLDFMQGHDEFDWNAVAGTDFDVDQWLQFPPEGVTNQDDNLIAGVLGRGVEEPTMSAEQALNWAINAEADATARQPDGRVQGEVPAQA
What are the official names of this protein?
Cutinase transcription factor 1 beta.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUB_ENDTX
Sequence: MSQSYNNIDGLLLLDKPFGITSFDAVYKIKKVLNVEKTGHCGTLDPASTGLLLVLMGKATKLQAKFMKKDKVYLSSFLLGMVTDSGDLDGKVISENSVLNINIEKIKKMVEMFEGEIFQIPPMYSALKYNGKKLCELARQGIEVERKPRKVTIKKFEVLSYDGDIVKVRIECSSGTYIRTLAQDLGNVLKCGATVKTLRREKIDIFDIKDALRFKDTDSADKIIKKLIPL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ATPA_GOSBA
Sequence: MVTIRADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLMIQEGSSVKATGKIAQIPVSEAYLGRVINALAKPIDGWGEISASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIFGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVTTFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKSSSQLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSAPLTVAEQISTIYTGTNGYLDSLEIGQVRKFLVELRTYLKTNKPQFQEIISSTKTFTEEAETLLKDAIQDQMERFRLQEQL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.