PharMolix/UniProtQA huggingface dataset:
Protein: MSMB4_PROFL
Sequence: MKVFFILIIFSFTLATCQGHCIGSIPLPEMEDGEDVPLRTCVDTHDEKKHLIVSTWKTANSFSCECRQDGMWCCKEYVAVA
What is the function of this protein?
Shows an slight inhibitory effect toward the metalloproteinase brevilysin H6, but does not inhibit the metalloproteinases thermolysin, HR1A and HR1B.
What are the official names of this protein?
Small serum protein 4, SSP-4.
What is the protein family that this protein belongs to?
Belongs to the beta-microseminoprotein family.
What are the subcellular locations of this protein?
Secreted.
Protein: URE2_TERTT
Sequence: MIPGEYDIKDGEITLNENRKTLTLTVANTGDRPIQVGSHYHFFETNPALSFSRDATRGFRLNIAAGTAVRFEPGQDREVELVEIAGDKTVYGFRGEIMGELEGGSHE
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3AA_CROAT
Sequence: ERLTKRYVELVIVADHRMFTKYNGNLKKIRKWIYQIVNTINEIYIPLNIRVALVRLEIWSNGDLIDVTSAANVTLKSFGNWRVTNLLRRKSHDNAQLLTAIDLDEETLGLAPLGTMCDPKLSIGIVQDHSPINLLVAVTMAHELGHNLGMVHDENRCHCSTPACVMCAVLRQRPSYEFSDCSLNHYRTFIINYNPQCILNEPLQTDIISPPVCGNELLEVGEECDCGSPRTCRDPCCDAATCKLHSWVECESGECCQQCKFTSAGNVCRPARSECDIAESCTGQSADCPTDDFHRNGKPCLHNFGYCYNGNCPIMYHQCYALWGSNVTVAPDACFDINQSGNNSFYCRKENGVNIPCAQEDVKCGRLFCNVNDFLCRHKYSDDGMVDHGTKCADGKVCKNRQCVDVTTAYKSTSGFSQI
What is the function of this protein?
Snake venom zinc metalloproteinase-disintegrin that causes hemorrhage by provoking the degradation of the sub-endothelial matrix proteins (fibronectin, laminin, type IV collagen, nidogen, and gelatins) and disturbances in platelet function.  The recombinant cysteine-rich domain interacts with the alpha-2/beta-1 integrin (ITGA2/ITGB1) (collagen receptor), and inhibits the platelet aggregation induced by collagen.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like atrolysin-A, Alpha-proteinase, Hemorrhagic toxin A, HT-A, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF_TUPAK
Sequence: MNFIPISLIFSGHGFGFNTNIFETNVINLAVVIGVVVSFVGDAVRELLKNRKETIVNNLREADNRALEAQEKLSQAKAQLADAQKKATEIREQGLVAAEQEKKLCIKQAEEDAARLKQVQQDTIRFQQQKAIQQISQQIVSLALQQVRQKLKMGASAPFHVSVNKSKIDLFKRSL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RBL_PROMP
Sequence: MSKKYDAGVKEYRDTYWTPEYVPLDTDLLACFKCTGQEGVPREEVAAAVAAESSTGTWSTVWSELLTDLEFYKGRCYRIEDVPGDPEAFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPIAFIKTCGGPPNGIVVERDRLNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDLTKDDENINSQPFQRWRERFEFVAEAVKLAQQETGEVKGHYLNCTANTPEELYERAEFAKELDMPIIMHDYITGGFTANTGLANWCRKNGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDNLRESFVPEDRSRGNFFDQDWGSMPGVFAVASGGIHVWHMPALLAIFGDDSCLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILMEAAKHSPELAIALETWKEIKFEFDTVDKLDVQG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity) (PubMed:22155772).  There are estimated to be 152 RuBisCO holoenzymes per carboxysome (PubMed:22155772).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: NUF2A_XENLA
Sequence: MDKLTFPIFPAADLVNFFRQNILTGTEAKNFNKNDIFPNPKPEMVQKLYMRILQQVFNYGVEQFYMVPMDLDIQYPHLVEGFAPVANILKLMARFLPMCRVYDFHPSDVLNPKGKRTLHSLSGIVNFLHFSATRKEVYFEYCSSYKSALENVRQLQKANQEAEIKIEKLTTVPPEQQAEFKALSSEIHDLQQIISQEYRAKDVAFQEKIAQRKTEFAEKNKRLNEQKLAIATMKEEQERMKSQIVESPEQRKSKTERMKETVHRLKQARQETNDKCDYYRDRVAFACMWQTDVQGYLKKLQGIDTNLEIHRKIREEIRHSEEQVVNLNLELKSLSNEDAQLKRIILVKKEKLAKVDIKNKKKQEDFNQQKQEILEVCSRIQEKRQVVHGRVAQVLQEIQQTIGKKEQLLETTEAGKKKCQEVITDFRAALEKYHDSLQKASERSADRRREKIAELNRRLSRR
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12514103).  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (By similarity).  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (By similarity).
What are the official names of this protein?
Kinetochore protein Nuf2-A, xNuf2, Cell division cycle-associated protein 1-A.
What is the protein family that this protein belongs to?
Belongs to the NUF2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase.
Protein: HMO_LISMO
Sequence: MKKVFITTGTEHYLRQLMANYTGGNVTLLQNFSQSLLYQESTGEKLFQEGAEYRVLQSSGSIKGFGVVVFEYIHLRDEEIPIFLQMYQRASLHFSETPGLQSTKLTKAMNMNKFLIISFWDSEVFFHDWKKSPLSKEITNIMRKNNTQSGFSHEDIYHYPEFSHDAK
What is the function of this protein?
Catalyzes the degradation of heme to biliverdin in the presence of a suitable electron donor such as ascorbate, with the subsequent release of iron.  Hardly any CO is released by the heme degradation reaction.  Binds heme (PubMed:24598731).  Allows bacterial pathogens to use the host heme as an iron source.  Release of iron from heme may play a crucial role in the pathogenicity of L. monocytogenes (Probable).
What are the official names of this protein?
Heme-degrading monooxygenase, Heme oxygenase, IsdG-type heme-degradation enzyme, Isd-LmHde.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_ORITB
Sequence: MSILSLVTAPDPILKKVSSPVDTVNDSIRQLIDDMLETMYHNHGVGLAAPQVAVSKRIIVLDLSKVDIEEDNITNSEYKYPLFMVNPIVKAISNQTVTAKEGCLSLPKQAIEVSRYHEIQVTYLDYYNKLKTLNAAGWLARAIQHEVDHLDGILLVDYLSNLKKEATLNTLSKIKDAAYDK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: AT7L1_BOVIN
Sequence: MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGRKQDKRNEGIFRNGPEDIQAIEKKQM
What are the official names of this protein?
Ataxin-7-like protein 1, Ataxin-7-like protein 4.
Protein: PLPP7_HUMAN
Sequence: MPASQSRARARDRNNVLNRAEFLSLNQPPKGGPEPRSSGRKASGPSAQPPPAGDGARERRQSQQLPEEDCMQLNPSFKGIAFNSLLAIDICMSKRLGVCAGRAASWASARSMVKLIGITGHGIPWIGGTILCLVKSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSPSLLDYLTMDIYAFPAGHASRAAMVSKFFLSHLVLAVPLRVLLVLWALCVGLSRVMIGRHHVTDVLSGFVIGYLQFRLVELVWMPSSTCQMLISAW
What is the function of this protein?
Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling.  Has no detectable enzymatic activity (By similarity).
What are the official names of this protein?
Inactive phospholipid phosphatase 7, Phosphatidic acid phosphatase type 2 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Nucleus envelope. Endoplasmic reticulum membrane. Membrane; Multi-pass membrane protein. Note=Both the N- and C-terminal are exposed to the cytoplasm/nucleoplasm.
Protein: LR75B_MOUSE
Sequence: MGARLGRRARADAPAAPSAGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLEGNLLTDILHRNVTFLNLVDPISHDLLVNLARDLQCPKKDHELWKSSDKICRQLIYHLTPHSKRKHHRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQHISRYLDTRGVELVVLDLSFTELSDELLHLLLPSLWALPRLTQLLLNGNRLTRAAARELTEAIKDTAKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLEPGGGMAETTAAVSTWGSAATEAGPEPQGCCAR
What is the function of this protein?
May suppress myogenic differentiation by modulating MYOG expression and Erk1/2 signaling.
What are the official names of this protein?
Leucine-rich repeat-containing protein 75B, Leucine-rich repeat-containing protein FAM211B.
What is the protein family that this protein belongs to?
Belongs to the LRRC75 family.
Protein: RT10_MARPO
Sequence: MTAKICIVIKSFENQRSGLLLNTRKIGLPKKQTLYTVLRSPHIDKKSREQFEMRIHKQLLVIETETHKLREKLNWLKLHDLLGVQVKIIFYYQTRLDKVCKS
What are the official names of this protein?
Ribosomal protein S10, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DCUP_CERS1
Sequence: MTKTMLRALKGETLPTPPIWLMRQAGRYLPEYRATRAQAGDFLSLCYTPDLAAEVTLQPIRRYGFDAAILFADILLLPQALGADLWFETGEGPRMSTITDMEGVTALKGRDDIHETLAPVYETCRILARELPKETTFIGFAGMPWTVATYMIAGRGSKDQAAAHKLKDTDRPAFEALMDRVTEATIEYLAKQVEAGCEVVKLFDSWAGSLKGQDFEDFAVAPAKRIVSELKARFPGLPVIAFPREAGEGYIGFAEKTGADCVAIDNSVSPEWAAEKVQAGRTCVQGNLDPKYMVTGGEELVQATKRVVEAFRNGPHIFNLGHGITPEADPENVTLLVETIRGK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_ECO7I
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RS15_PSEAB
Sequence: MALSVEEKAQIVNEYKQAEGDTGSPEVQVALLSANINKLQDHFKANGKDHHSRRGLIRMVNQRRKLLDYLKGKDVSRYTALIGRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PUR3_MYCTO
Sequence: MQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARVVAVGVDRECRAAEIAAEASVPVFTVRLADHPSRDAWDVAITAATAAHEPDLVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVKVTGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAVAALATHGVTVVGRTATMGRKVTIG
What is the function of this protein?
Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
What are the official names of this protein?
Phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase, GAR transformylase, GART.
What is the protein family that this protein belongs to?
Belongs to the GART family.
Protein: CYC10_CLITE
Sequence: GIPCGESCVYIPCTVTALLGCSCKDKVCYKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cliotide T10.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: MTNB_BOTFB
Sequence: MTSQNPTQEPENNDHLIISQDSQHPANLIPELCAKFWHLGWVTGTGGGASIRKDDLVYLAPSGVQKELMKPEHIYVLDITKQLDPKQRIYLRSPPNLKPSQCTPLFMAAFTKRNAGCCIHTHSKWAVLITLLLESAPNTTMFEINNIEQIKAFGKGYTKSGNLGYHDTLRIPVIENTPHEEDLTEYLEEAMEKYPDTYAVLVRRHGVYVWGESVHKAKTQCESLDYLFQIAVDMKKLGLPWLSDVKPIA
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_XANC8
Sequence: MPAKTTSARLTHLDDAGLPTMVDVSDKQVTARSATAESRVHFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHELIPFCHPLPIDGCRFEIDWAGAQVLQIVCTVRCVHRTGVEMEALTGASVAALTVYDMCKALSHTMRIGPTKLLSKRGGKRDIGAAR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: LAX3_MEDTR
Sequence: MTSEKVETVVAGNYLEMEREEEGSKSTTGKLSKFFWHGGSVYDAWFSCASNQVAQVLLTLPYSFSQLGMLSGILFQIFYGLMGSWTAYIISVLYVEYRTRKEREKVDFRNHVIQWFEVLDGLLGKHWRNLGLFFNCTFLLFGSVIQLIACASNIYYINDHLDKRTWTYIFGACCATTVFIPSFHNYRIWSFLGLVMTTYTAWYMTIASILHGQAEDVKHSGPTKLVLYFTGATNILYTFGGHAVTVEIMHAMWKPQKFKMIYLIATLYVMTLTLPSAAAVYWAFGDNLLTHSNALSLLPRTGFRDTAVILMLIHQFITFGFACTPLYFVWEKFLGVHETKSLLKRALVRLPVVIPIWFLAIIFPFFGPINSTVGSLLVSFTVYIIPALAHMVTFASAPARENAVERPPSFLGGWVGLYSVNVFVAVWVLVVGFGLGGWASMLNFVHQIKTFGLFAKCFQCPPHKA
What is the function of this protein?
Carrier protein involved in proton-driven auxin influx.  Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex (By similarity).  May be involved in lateral roots and nodules formation.
What are the official names of this protein?
Auxin transporter-like protein 3, AUX1-like protein 3, MtLAX3.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.1) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BOLA1_HUMAN
Sequence: MLSGRLVLGLVSMAGRVCLCQGSAGSGAIGPVEAAIRTKLEEALSPEVLELRNESGGHAVPPGSETHFRVAVVSSRFEGLSPLQRHRLVHAALAEELGGPVHALAIQARTPAQWRENSQLDTSPPCLGGNKKTLGTP
What is the function of this protein?
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity).  Probably acts together with the monothiol glutaredoxin GLRX5 (PubMed:27532772).  May protect cells against oxidative stress (PubMed:22746225).
What are the official names of this protein?
BolA-like protein 1, hBolA.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
Protein: BIOB_PARL1
Sequence: MTARTDPGALRHDWTREELQALFDLPFNDLLFEAQLVHRRWFKADEVQMSTLLSIKTGGCPEDCGYCAQSSKFDTGLKASKLMEVEKVLAEARKAKEAGATRYCMGAAWREPKDRDMDMVCAMVEGIKDMGMETCMTLGMLSGQQVHRLAQSGLDYYNHNIDTSEEYYPKVISTRTYQDRLETLERVRNAGINVCSGGIVGMGESPSDRIGMLMTLANLEEHPQSVPINMLMPVEGTALGASEKIDPIDFVRLIAVARIAMPQSVVRLSAGREHMSEETQALCFLAGANSIFIGEKLLTTKNPEADKDQRLFAKLGIRSMPAHSCPSEKDVSADRKAG
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: MED27_MOUSE
Sequence: MADVLSVGVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIANFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHLSRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNESVYTEDGKLDIWSKSSYQVFQKVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFRTLEAFHDTCRQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 27, Cofactor required for Sp1 transcriptional activation subunit 8, CRSP complex subunit 8, Mediator complex subunit 27.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 27 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRAAH_PSEPF
Sequence: MNHYLTPDLCDAYPELVQVLEPMFSNFGGRDSFGGEIVTIKCFEDNSLVKEQAELKGNGKVLVVDGGGSLRCALLGDMIAEKAAKNGWEGLVIYGCIRDVDVIAQTDLGVQALASHPKKTEKRGLGDLNVPVTFAGVTFHPGQYIYADNNGVIISPSPLKMPE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: ENO_FERNB
Sequence: MYVEIIDVRAREVLDSRGNPTVEVEVLLEDGSFGSAIVPSGASTGKFEALELRDGDKKRYMGKGVLKAVEHVNEIIAPRVVGLNAFDQVYLDKVLLELDGTENKSKLGANAILGVSMAVARAASESAGVPLYKYLGGANAKILPVPFMNVINGGAHADNSLDIQEFMLVPAGAPSFKEALRYGAEVFHTLKKILKDAGHVTAVGDEGGFAPNLSSNEEAIQVLIEAIKKAGYEPGKDIYIALDCAASEFYNEETGKYNIDGTEKTGDELIEYYSMLIDKYWPVIISIEDPFEQEDWDSYVKFTQKVGGKVQIVGDDLYVTNVKRLEKGIELFASNSILIKLNQIGSVTETLDAIEMAKTAGMTNVISHRSGETEDTFIADLAVATNAGMIKTGSLSRSERIAKYNRLLRIEEELGDAAIYKGLGAFYSIKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RF3_BUCAI
Sequence: MFDSNHEQELSKRRTFAIISHPDAGKTTITEKMLFFGKVIRVPGTIKGRGSGKYAKSDWMNIEKERGISITTSVMQFTYKNILMNLLDTPGHQDFSEDTYRILTAVDCCLVVIDAAKGIEERTRKLMDVARIHNTPIITFINKLDRDSRDPIEILDEIEKELKLHCIPISWPISCGKNFRGVYHIYDKIIHLYKSKFRKNFLTLDSFLDGSLNEYLGADLSIHIRQELELIMNVYSKFNKEKFLKGITTPIFFGSALGNFGIDHLLDSLIKWAPSPLYRQSNKRIIKPQERKFTGFIFKIQANMDLKHRDRIAFMRIVSGQYTKGMKLTHVRIKKNIIISDAFSFLAGERISINKAYPGDVIGLHNHGTIKIGDTFTQGEEIKFIGIPSFAPEIFRLIYLKNPLKQKQLKKGLVQLSEEGTVQVFRPILNNDLILGAIGILQFDVVIERLRIEYNIDAVYKKVNIVLARWINYGNHHSLYNLKKSYSSYLAYDISNSLIYLAPSSANLNIVMSQNSDISFNATREQ
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity).
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPN2_RAT
Sequence: MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLEPLRGHYFLFDCPGQVELCTHHTSLRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHVNLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFSHYRQLNEKLVQLIEDYSLVSFIPLNIQDKDSIQRVLQAVDKANGYCFGVQEQRSLEALMSAAVGADFHFSSTLGIQEKYLASSDQTAEQEAMQL
What is the function of this protein?
Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 2, ATP-binding domain 1 family member B.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: NA2H_HALCG
Sequence: VACRCESDGPDVRSATFTGTVDLWNCNTGWHKCIATYTAVASCCKKD
What is the function of this protein?
Is potently lethal to crabs, although it showed neither lethal activity in mice nor hemolytic activity.  May bind to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction.
What are the official names of this protein?
Delta-halcutoxin-Hcg1a, Delta-HCTX-Hcg1a, Halcurin.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.