PharMolix/UniProtQA huggingface dataset:
Protein: SHO1_COLGM
Sequence: MEQSRAQYGRKGINMGNIIGDPFALATVSISMLAWIIAFISSIIATTQVTNDSGSFPPFAWWTVVYMSFVIAGVFVVVASDTAQTYHVALTGYLGAALALNSLTIHSLIYSANGARQAAGAGFILMAMVTIVWIFYFGSAPSAKPRAYLDSFALQKESHSRQMMYGGGRPETSTSVQPPQMYTSAQLNGFENPSPVQGISTTQARNSVVAPTFNATPPATKGPGQDQEVVPPTEYPYRAKAIYSYEANPDDANEISFSKHEILEVSDVSGRWWQARKETGETGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DESB_ASPDE
Sequence: MGTETEYLQSIQQALKSLTTAANNCQLTYTHAVGQDVHSLCAREAVRKTLVLEAYKFLQIAQGPVDAAVTCFEQTAHLASVRALLEAGVFEVLPTDGTPRTMKEVAEKLDVDESLLARLMRHASLYGPLEETGPGSYRHTPFSLVYLRPEIRGMVRFAMDEHMPAHLKLHEYLQQTSWTAPSSSTNNPYTHAHSITGTSMFANLSAPSNKHRLDAFNDAMTVQATTAIWMIDLFPFHEVLSPSASADTVLAVDIGGGTGRAISRIRSLAGNLPGRYILQDQAHVISNLPSPSPSSYLDGIETMTHDFFTPQPVAGAQIYLIRRCLHNWPEESVIRILRNIVPAMARTNSRLLIEEIIVPESNSGIEEGWMDMIMMALGAKQRTLEEWKGVLGTAGLEVVTVYRVDGICHGLIEARVKSE
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the bicoumarin desertorin (PubMed:26389790).  The non-reducing polyketide synthase desS first catalyzes the formation of the pentaketidic 4,7-dihydroxy-5-methylcoumarin from acetyl coenzyme A and 4 malonyl coenzyme A molecules (PubMed:26389790).  Further O-methylation by desB leads to the formation of 7-demethylsiderin (PubMed:26389790).  Then, an oxidative phenol coupling catalyzed by the cytochrome P450 monooxygenase desC forms the 6,8'-dimer M-desertorin A via dimerization the monomeric precursor, 7-demethylsiderin (PubMed:26389790).  M-desertorin A is further converted to M-desertorin C (PubMed:26389790).
What are the official names of this protein?
O-methyltransferase desB, Desertorin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: GYRB_MYCBP
Sequence: MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDSKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.  Relaxes negatively supercoiled DNA in an ATP-independent manner.  A linear reaction intermediate can be trapped in the presence of the antibiotic ciprofloxacin (PubMed:7503546).  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_DICTD
Sequence: MIRVAIPTGRMLEQALDFLRNFDDRLLDEEKGRKLRIHGERFEVFLAKPWDLPLYVEERVVDLGIIGRDVIWEQEKNVVNLISLPFGYCKMVIAGYPYVSLKGNGKEIRIATKYENITKKLLENRWGKIKIIKLNGSVELGPILNISDLIVDIVETGKTLRDNGLEVKEVLFESSACLISNVVSFAYLRKEILSFVKEVRKLNDKCN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR4Q3_HUMAN
Sequence: MKKEQDSNVTEFVLLGLSSSWELQLFLFLLFLFFYIAIVLGNLLIVVTVQAHAHLLQSPMYYFLGHLSFIDLCLSCVTVPKMLGDFLQQGKSISFSGCLAQIYFLHFLGASEMFLLTVMAYDRYVAICNPLRYLTVMNPQLCLWLVLACWCGGFIHSIMQVILVIQLPFCGPNELDNFYCDVPQVIKLACMDTYVVEVLVIANSGLLSLVCFLVLLFSYAIILITLRTHFCQGQNKVFSTCASHLTVVSLIFVPCVFIYLRPFCSFSVDKIFSLFYTVITPMLNPLIYTLRNTDMKTAMKKLRIKPCGIPLPC
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4Q3, Olfactory receptor 4Q4, Olfactory receptor OR14-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSRA_SHEDO
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQNEKSDPSSESGNF
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPQ_ECO81
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPNSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPARYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: TAD3_SCHPO
Sequence: MVKTNISKNSPKEATVPELDWPFKLIKSHLETRKLETENVWIACFEPKYASKVTQYVKQIRSKQKESLLHCNRLRRIQDENGSLELQIIICPEKSMTANEIGKDFEDLGIVSKMIFLYAVPAFPPLTDEQFHEWNSVWPVSYRKHVQRQDVFTVHELKRIESILEDLINAAGASHKHGEIGCAAAIYDPTTDTVLAVSVDERSKLKNPINHCVMNAINLVAKRELSRRQNRTDGSKDRYLCKDLTVVMTHEPCVMCSMGLLHSRIRRLIYCKKQPLTGGIESLYGIHWRAELNHRYLAYSGWNKPVPSIKENIHV
What is the function of this protein?
Deaminates adenosine-34 to inosine in many tRNAs.
What are the official names of this protein?
tRNA-specific adenosine deaminase subunit tad3, tRNA-specific adenosine-34 deaminase subunit tad3.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL33_ORITI
Sequence: MSRKKKKVLVKLVSSAGTGVFWVKQRNPKTQTEKLSFRKYDPKVRKHVQFTEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: HACL2_MOUSE
Sequence: METSAAAASAGGFFPSFLLLAFGTLVAAVLGVAHRLGLFYQLMHKVDKTSIRHGGESVAAVLRAHGVRFVFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAVARLTGTVGVAAVTAGPGLTNTVTAVKNAQVAQSPVLLLGGAASTLLQKRGALQAIDQMSLFRPLCKFCASVRRVRDIVPTLRTAIAAAQSGTPGPVFVELPLDVLYPYFMVEKEMIPTKLPNSLMGRVVVWYLQNCLANLFVGAWEPRPEGPLPLDIPQASPQQVQRCVEILSRAKRPLLVLGSQALLPPTPANKLRAAVETLGVPCFLGGMSRGLLGRNHPLHIRQNRSAALKKADVVVLAGAVCDFRLSYGRVLNRKSSIIIVNRNRDDLLLNSDIFWKPQEAVQGDVGSFMIKLVEGLQGQMWSSDWAEELRKADQQKEQTYRDKALMPVLQHLNPVWVLQQVEETLPDNALLVVDGGDFVATAAYLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCQPEAEVWCLFGDGAFGYSLIEFDTFVRHKVPVIALVGNDAGWTQISREQVPRLGSDVACSLAYTDYHKAAMGLGAQGLILSRDNKDQVVKVLREGQQLCQDGHAVVVNILIGRTDFRDGSISV
What is the function of this protein?
Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner.  Involved in the phytosphingosine degradation pathway.
What are the official names of this protein?
2-hydroxyacyl-CoA lyase 2, Acetolactate synthase-like protein, IlvB-like protein.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: IHFA_SHESM
Sequence: MALTKAEMAEHLFETLGINKRVAKEMVESFFEEIRGALESGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPISARRVVTFRPGQKLKTRVEASNAGK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: LSPA_FRATO
Sequence: MNLLRPKLKYFILAILIIAADLYTKYLANTYLEFAQSLKITSFFNLTLLYNHGAAFSLLSNDQTSWQMIMFSTISLIAAIVLIYLIIKQPITEKINLFSFALILGGALGNFYDRAFQGYVIDFLDFHIGNYHWPSFNIADSAITCGVVILIAASLFTKKKS
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURG_VIBCH
Sequence: MMNKNKKLMVMAGGTGGHVFPGLAVAKQLQQQGWQIRWLGTADRMEAELVPKHGIEIDFIQVKGLRGQGLMRLLKAPFQIVNAILQARRHLLTYQPDAVLGMGGYVSGPGGIAAWLLGIPVVLHEQNAVAGLTNQWLAKIARRVFQAFPGAFADASVVGNPVRQDVVQLAAPEQRFATRNGAIRILVMGGSQGARILNQTLPAVMAALGEGYEIRHQAGKNSQQDVAEAYAAAGVESAQVTEFIDDVADAYAWADLLICRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGAAKMIEQPELSVEKLTQMVRELDRAQLLSMAQKARQAAKLDADKVVAQAIIAITE
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PSPB_CANLF
Sequence: LLWLLLLPTLCGLGAADWSAPSLACARGPAFWCQSLEQALQCRALGHCLQEVWGNARADDLCQECQDIVRILTKMTKEAIFQDMVRKFLEHECDVLPLKLLTPQCHHMLGTYFPVVVDYFQSQINPKIICKHLGLCKPGLPEPEQESELSDPLLDKLILPELPGALQVTGPHTQDLSEQQLPIPLPYCWLCRTLIKRIQAMIPKGVLAVTVGQVCHVVPLVVGGICQCLGERYTVLLLDALLGRMLPQLVCGLVLRCSHEDSAGPALASLPSEWSPQESKCQLCMFVTTQAGNHSEQATPQAIRQACLSSWLDRQKCEQFVEQHMPRLQTLASGGRDAHTTCQALGACRTTFSPLQCIHIPHF
What is the function of this protein?
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.  SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
What are the official names of this protein?
Pulmonary surfactant-associated protein B, SP-B, 6 kDa protein, Pulmonary surfactant protein 18, SP 18, Pulmonary surfactant-associated proteolipid SPL(Phe).
What are the subcellular locations of this protein?
Secreted, extracellular space, surface film.
Protein: PSBT_SARHE
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKILTKKTK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SCMU_MYCS2
Sequence: MLASVALAALAGVGTPHATADDASPLVPLVDAAAQRLQTADPVAASKFRSGGAIDDPDREQQVIAAVTGDATRHNIDPGYVHDVFRNQIDATSSVEHTRFAQWKLDPAAAPSSAPDLSESRQKIDTLNRTMVDEIARQWPVLHSPVCRPDLDRALDAVATARGFDPVYRHALEYATHSYCR
What is the function of this protein?
Catalyzes the Claisen rearrangement of chorismate to prephenate.  May play some role in the pathogenicity.
What are the official names of this protein?
Secreted chorismate mutase, CM.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOC_PSEA7
Sequence: MPDLSAPLLAPHGVAALPDKRQVAASFSRAAASYDAVAELQRGVGESLLAALPEGFAPRRWVDLGCGTGYFSRALAQRFGGGEGLAVDIAEGMLRHARARGGASHFIGGDAERLPLRDGSCDLLFSSLAIQWCADLPAVLAEARRVLRPGGVLAFSSLCVGTLGELRDSWRVVDGFVHVNRFRAFADYLQHAAGSGLLPLVLRHEDRVLHFPDLRSLTHELKALGAHNLNPGRPDGLTGRQRIRALVAAYERFRQPGGLPATYRVVFGVLRKDS
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: GLUQ_CITK8
Sequence: MTNAHYIGRFAPSPSGELHFGSLIAALGSYLRARSQHGIWRVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDILWQSQRHDAYRDALAWLRQQNLSYYCTCPRARIQRIGGVYDGHCRTLQHGPENAAVRIKQFSPVMQFHDVLRGDIQADPLLAREDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQQFGWRAPDYIHLPLALNEQGAKLSKQNHAPALPEGDPRPVLIAALRFLGQNATAQWQDMHTDELLQYAVDNWTLTTVPESASVNPAFSNASC
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: RECA_HELMI
Sequence: MAAGDNKLQALQQALNSIEKAFGKGSIMRLGEASAKLLVEVIPTGSIALDMALGIGGVPRGRIVEVYGPESSGKTTVALHIIAEAQKMGGMAAFIDAEHALDPVYARNLGVDIDNLLVSQPDTGEQALEICEALVRSGAIDVVVIDSVAALVPKAEIDGEMGDAHVGLQARLMSQALRKLTGVVSKSKTCCLFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRKVDTLKQGSDMIGSRTRVKVVKNKVAPPFKVADFDIMYGEGISREGSLVDLAVDMGIVEKSGAWYSYKGDRLGQGRENVKEFLRNHPALAAEIESMIRGRTESARLAAAAAPAAGDGE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRF4_ARATH
Sequence: MDLQLKQWRSQQQNESEEQGSAATKISNFFFDQIQSQTATSAAAAPLPLFVPEPTSSSSFSCFSPDSSNSSSSSRFLKMGNFFSWAQWQELELQALIYRYMLAGASVPQELLLPIKKSLLHQSPMHFLHHPLQHSFPHHQPSWYWGRGAMDPEPGRCKRTDGKKWRCSRDVVAGHKYCDRHIHRGRNRSRKPVETATTTITTTATTTASSFVLGEELGHGPNNNHFFSSGSSQPLHLSHQQSCSSEMKQESNNNKRPYEANSGFSNGRSDDGHILRHFFDDWPRSSDSTSSPMSSSTCHLSISMPGNNTSSDVSLKLSTGNEEEEENMRNNNNEREQMNWWSNGGNHHNNMGGPLAEALRSASSTSSVLHQMGISTQVFH
What is the function of this protein?
Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues.  Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation.
What are the official names of this protein?
Growth-regulating factor 4, AtGRF4, Transcription activator GRF4.
What is the protein family that this protein belongs to?
Belongs to the GRF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RMR4_ARATH
Sequence: MIRSSIVILSLLLISHLVSAKVLLIGNSTSLSFDDVEATFTPMIKRSDQGGVLYVAEPLDACSDLVNTVNVKNGTTVSPPYVLIIRGGCSFEDKIRNAQKAGYKAAIVYDYEDFGFLVSMAGNPSGVLIYGTFVSKATGEVLKEYAGRTDFEVWLMPSFETSAWSIMAISFISLLAMSAVLATCFFVRRHRVRRRRILALNGNDFHRMPKSMIIRMPTTIFNGICDEATTSILCCICLENYEKGDKLRILPCHHKFHVACVDLWLGQRKSFCPVCKRDARSISTDKPPSEHTPFLSRTPSMTPTSSFLLSSSSTTPLQSSHELPISIRVDPSLPSTSMQPHTVPMYLSHSRSHTSFQNGSNRFSRPIPVSRSSADLRNAVSQRSYNSPHQVSLPRFLHSRYTHILGPGNASRSQVVGLLTSQREHSLHQNDSRRSFIHFASASSLPGW
What is the function of this protein?
Involved in the trafficking of vacuolar proteins.  May function as a sorting receptor for protein trafficking to the protein storage vacuole (PSV) (By similarity).
What are the official names of this protein?
Receptor homology region, transmembrane domain- and RING domain-containing protein 4, AtRMR4.
What are the subcellular locations of this protein?
Prevacuolar compartment membrane. Protein storage vacuole membrane; Single-pass type I membrane protein.
Protein: SYA_COXBR
Sequence: MNSNQLRETFLNYFKQLDHEVVPGSSLIPENDPTLLFTNAGMVQFKDVFLGVETRPYQRAVSIQPCMRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIKFAWDFLTNVLKLPPQRLWVTVFQDDFESESIWLKEMKINPERFSRCGEKDNFWQMRDTGPCGPCTEIFYDHGPTISGGPPGSAEADGDRYVEIWNLVFMQYNRDAKGNLLPLAKPSVDTGMGLERLTAVMQGVHDNYDIDLFQYLLKALRTLLKTEDLHNTSMRVIVDHIRSVAFLIADGVIPSNEGRGYVLRRIIRRAVRHGYKLGQEEPFFYQLTKPLLEEMGGAYPLLRKSQALIEQTIKQEEIQFSNTLTKGLKILDHEMAGLPSRQIPGNLIFQLYDTYGFPPDLTADIARERDFVMDYAGFDKAMERQREQSQQAHQFVANYAQKASIGGETQFVGYETLNSQANVISLLQNDQPINRLNESEKGVVVLDRTPFYAESGGQVGDQGFLYFEKGSFRVKDTKKQGDIYLHIGEMLQGHLNVKDKVRAEVDVSRFDIMRNHSATHLLHEALRRVLGERVMQKGSLVEAKRLRFDFSHAKPLTPEELQAVERLVNQQIQANLLSTIEVMTPEEAKKKGALALFGERYGKEVRVLEMGDFSTEICGGTHTERTGEIGLFKIVSESGCAAGIRRIEALTGKAALDYIESAEQQLRSLSDLLKTNRKNLAAKLSQILEDHRKLEKELAKLKQRLASQQLESLINQVVDVHDIRTLAIRLEAVDRETLRAIVDQLKQKLGKAAIVLATIEEGRIQLVAGVTKNCLEHFNATELLAPIAEKVGGRSGGRPDLAQGAGERPENLEAALAAVPKWIEKKLKE
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM4C_HUMAN
Sequence: MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
What is the function of this protein?
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling.  PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'.  Required for normal brain development, axon guidance and cell migration (By similarity).  Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
What are the official names of this protein?
Semaphorin-4C.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Postsynaptic density membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein.
Protein: RPOB_BLOPB
Sequence: MVYSYTEKKRIRKDFGKRPQVLDIPYLLSIQIDSFQKFIKQDPEEPCGLEAAFRSVFPIKSYNGNAELQYIKYQLGEPTFDVKECQTRGATFSAPLRVRLCLIIYEREGLNNIIKNTKEQEVYMGEIPLMTNNGTFIINGIERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDLKDNLFVRIDRRRKLPVTVILRALNYTTDQILNIFFNKVIYEIQNNTLYMHLIPERLRGETASFDIAVNGVIYVKKGRRIAAKHIRQLKKDKISKIEVPMDYIIGKVVIKDYFDKNTNIPIVTANTEISSDILHNLIRSGYESIETLFSNDLDYGNYISETLRIDATTNKFDALVEIYRVMRPGEPPTKEAAEYLFENLFFSEERYDLSSVGRMKFNRSLQRVQIEDLGTLKKDDIVDVIKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDVLTPQDLINAKPISAAVREFFTSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYARANKYGFLETPYRKVQNGVVSNDIHYLSAIEEGDFVIAQANTNLNSIGEFIDDLVTCRNKGESGLFKKDQVDYMDVSTQQIVSVAASLIPFLEHDDANRALMGANMQRQAVPVLCSEKPLVGTGMERAVAIDSGVTVVAKRGGVIKYVDASRIVIHVNKNETHTEESGIDIYQLTKYIRSNQNTCINQRPCVSLGELVEHGDVIADGPSTDLGELALGQNMRIAFMPWNGYNFEDSMLVSERVVQEDKFTSIHIQELTCVSRDTKLGPEEITADIPNVGETALSKLDESGIIYIGAEVIGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVCGTVIDVQIFTRDGINKDKRSLIIESEKLKQVKKDLSEELQIFESALFDRVCDVLMTSGIDKKKLFETSRNAWLDLVLSDPEKQYQLSQLTKQYFDLKRMFEKKLEIQHRKITQGDELAPGILKIVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPIEDMPYDQHGIPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINFMLQQHKEANQLRRFMQQAYNLGEGSRQHINLNSFSDIEILKLAKNLKKGMPIATPVFDGATEKEIKDLLKLSGLPSSGQITLFDGCTGEAFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLTVKSDDVNGRTKMYKNIVDGNHMMEPGMPESFNVLLKEIRSLAINIELED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GREA_VIBVU
Sequence: MEKVPMTARGEQLLRKELERLLKRRPLITEAIAEARELGDLKENAEYHAAREEQGICEAQIRDIEYKLSVAQVIDVSKMENNGKVIFGATVTLIDCDTEEEKTYQIVGDDEADIKSGRISVNSPIARGLIGKMEGDEVAISTPGGMKDFEIDSVEYR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.