PharMolix/UniProtQA huggingface dataset:
Protein: ATPFD_MYCBT
Sequence: MSTFIGQLFGFAVIVYLVWRFIVPLVGRLMSARQDTVRQQLADAAAAADRLAEASQAHTKALEDAKSEAHRVVEEARTDAERIAEQLEAQADVEAERIKMQGARQVDLIRAQLTRQLRLELGHESVRQARELVRNHVADQAQQSATVDRFLDQLDAMAPATADVDYPLLAKMRSASRRALTSLVDWFGTMAQDLDHQGLTTLAGELVSVARLLDREAVVTRYLTVPAEDATPRIRLIERLVSGKVGAPTLEVLRTAVSKRWSANSDLIDAIEHVSRQALLELAERAGQVDEVEDQLFRFSRILDVQPRLAILLGDCAVPAEGRVRLLRKVLERADSTVNPVVVALLSHTVELLRGQAVEEAVLFLAEVAVARRGEIVAQVGAAAELSDAQRTRLTEVLSRIYGHPVTVQLHIDAALLGGLSIAVGDEVIDGTLSSRLAAAEARLPD
What is the function of this protein?
This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta).  Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0) (By similarity).
What are the official names of this protein?
ATP synthase subunit b-delta.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PHK_BRUSU
Sequence: MPAKGPLTPQQLSLINRYWRAANYLSVGQIYLMKNPLLREPLQPEHIKPRLLGHWGTTPGLNFIYAHLNRIIQQRNANVIYICGPGHGGPGMVANTYLEGTYSEIYPAISEDEAGMERLFRQFSFPGGIPSHAAPETPGSIHEGGELGYALVHAYGAAFDNPDLVVACVVGDGEAETGALATSWHSNKFLNPARDGAVLPILHLNGYKIANPTVLARLSDDDLDNLFRGYGYEPFFVEGSEPADMHQKMAATLDTIFQRIQDIKKNADVHSPERPRWPMIILRSPKGWTGPKTVDGLVVENYWRAHQVPVANCRENDAHRKILEDWMKSYDPSDLFDEKGALKPELRALAPKGEARIGANPHANGGLLRKELHMPDFRQYAVNVTEPGAIEAQSTKILGDFLRDVMKLNETEKNFRIFGPDETASNRLGSVLEATNRVWMAETLDMDDHLAADGRVMEVLSEHLCQGWLEGYLLSGRHGFFSCYEAFIHIIDSMFNQHAKWLQVARELEWRKPISSLNYLLTSHVWRQDHNGFSHQDPGFVDLVANKSADIVRVYFPPDANTLLWVGDHCLKTWNRVNVIVAGKQPEPQWLTMAEAEKHCEAGLGIWEWAGTEDGLEPDIVMACAGDVPTMETLAAVDLLRQSLPHLRIRVVNVVDLMVLQSPHQHPHGISDEEFDRMFTTNRPVIFAYHGYPYLIHRLVYKRTNHSNFHVRGFIEQGTTTTPFDMTVLNELDRFHLAMEAVERLPLGESVAKPLIDNFTEKLALHKDYIRQHGEDMPEIRDWKWTWPR
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: PQQE_AZOVD
Sequence: MSAPGSSCTEPGPPLWLLAELTYRCPLQCPYCSNPLDFARHGAELSTAEWIEVFRQARELGAAQLGFSGGEPLVRQDLSELIGAARGLGYYTNLITSGIGLSEARIAEFATAGLDHIQVSFQAADAELNDLLAGSGKAFARKLAMARAVKAQGYPMVLNFVTHRHNIDAIERIIELCLELEADYIELATCQFYGWAELNRAGLLPTRAQLERAERITNQWREKLAAQGHPCKLIFVTPDYYEERPKACMGGWASLFLDIAPDGTALPCHNARMLPVQFPNVREHSLRHIWYDSFGFNRFRGDDWLPEPCRSCDEKGRDFGGCRCQAFLLTGDAEATDPVCAKSAHHGLILDARRQAEEAPLGLERLVHRNARTSEIICRSRSE
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: HBA_SUNMU
Sequence: VLSANDKANVKAAWDKVGGQAANYGAEALERTFASFPTTKTYFPHYDLSPGSAQVKAHGKKVADALTKAVGSMDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHHPADFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MURC_SALSV
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLTSLGATIFFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYHGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQGMPDLHVTLNAPGRHNALNAAAAVAVATEEGIADDAILRALESFQGTGRRFDFLGEFPLEPVNGKAGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRYTRTRDLYDDFANVLTQVDALLMLDVYPAGEAPIPGADSRSLCRTIRNRGKIDPILVSDPAQVATMLAPVLTGNDLILVQGAGNVGKIARYLSEIKLKPQIQEEEQHG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_CVPFS
Sequence: MANQGQRVSWGDESTKIRGRSNSRGRKSNNIPLSFFNPITLQQGSKFWNLCPRDFVPKGIGNRDQQIGYWNRQTRYRMVKGQRKELPERWFFYYLGTGPHADAKFKDKLDGVVWVAKDGAMNKPTTLGSRGANNESKALKFDGKVPGEFQLEVNQSRDNSRSRSQSRSRSRNRSQSRGRQQSNNKKDDSVEQAVLAALKKLGVDTEKQQQRSCSKSKERSNSKTRDTTPKNENKHTWKRTAGKGDVTRFYGARSSSANFGDSDLVANGSSAKHYPQLAECVPSVSSILFGSYWTSKEDGDQIEVTFTHKYHLPKDDPKTEQFLQQINAYARPSEVAKEQRKRKSRSKSAERSEQEVVPDALIENYTDVFDDTQVEMIDEVTN
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the alphacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Host nucleus, host nucleolus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: DNLJ_PROM1
Sequence: MNSNFNQHFERIKELRALLNKANYSYYVLDSPEIDDAVYDQLYRELIEIENIHPSLITDDSPSQRLGGVPSKGFKNVEHNIPLLSLDNAFNLNELESWYGRISKLISSENKNIKKVDDLELICELKIDGNAISLRYENGILTRAATRGDGKTGEDITTNIRTISTIPLRLLLENPPSWVEIRGEAFMPNNIFNKLNIERKNTDQPLFANPRNSCAGTLRQLDPKIVASRKLDFFAYSLYFPENWEPTDNNFKKPISQSESLEFLKNIGFKVNTTYETTKTLNEANKYYKYWEVKKDFLAYATDGIVVKIDKFDIQNLLGATNKAPRWAIAVKYPAEEKATKLRKIIFQVGRSGAVTPVAEFESIELAGTSVNRATLHNAKRLASLDLHYEDTIIVRKAGEIIPEVIRVIKEFRKVDAKLVQLPQNCPECNSKLILESNEAITKCINYGCEAKLKGLLRHWVSKGSMNIDGLGEKIINQLVNEGYVKSIADLYKLEIDSLLELERFGEKSANNLLIEINESKNKNWHKQLYGLGIPHIGEANAKSLSNNFNSIEELNAIAKESPEKISNIYGFGNEMKDSIVKWFDDSNNQTLIKELKAIGFSLKESLDSNYNSNQSNVFDGKSFVLTGTLDSLTRDEAKELIESAGGKVSSSISKKTDFLVSGEKAGSKLNKAQELGVKIINENELKLLL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: TILS_PSEPK
Sequence: MINLTPWLNAPTWYVAFSGGLDSTVLLHLLAEYARNHASPPLRAIHIHHGLQAAADAWPAHCQAICDNFDVELQVIHVQVSPGASLEQAARDARYAAFRQVLGPGDILFTGQHRDDQAETLLFRLLRGAGLRGLAAMPGQRALGQGSLVRPLLACSRQHLQEYAQAQGLTWIEDPSNVDTQFARNYLRGEVMPHLQQRWPQASQNFARAAEHLGEALGLLDELAQEDLALAGKGAPLAWPGLDSLDLAALLALSPARQRNALQYWLSQRTRLPDTRHWAGWADLRDAGADARPVWRLADGRLVRSHGRIWWLSGDWLQQPAGSLAWPDPDGPLRLPGNGCVRLVGAAVPSGLRIAYRQGGEMLEVPGRGRRDLKRLLNEQQVPHFLRSRLPLLYHGECLLAVANLPGLVQADCQLHWQLPTNAQGLS
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKOY_BACSU
Sequence: MYSGNKVVISWIVSIGFVGMPEFMSSKTFALCRQRSFLHGPAGIRSDEEKENNFFGRVSFMDAALLLEYGWVLLVLIGLEGILAADNALVMAVMVKHLPEEKRKKALFYGLAGAFVLRFGSLFAISFLVNVWQVQAIGAIYLLYISASHLLKRYVFKKEDTHKETKQSGFWPTVLKVELADIAFAVDSILAAVALAVTLPGTSLPKIGGLDGGQFLVILAGGIIGLVIMRFAASMFVKLLKERPSLETAAFVIVGWVGVKLALYTLAHRDIAVVSEHFIHSGTWKLIFWGVLAAIAVCGWFMSGGKKQPEGAQNEQKNSTRERA
What are the official names of this protein?
Uncharacterized membrane protein YkoY.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACP_DEIGD
Sequence: MATFDEVKEVIVDKLGVDADKVTPEARFVEDLGADSLETVELIMGLEDKFGISISDEDAEKIRTVQAAVDYIGSKQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_ARTBC
Sequence: MKFSIAAAVLALASAVVAHPGAGYVSTPEKEANFQQNFQKFVTACGNGNQVSCCNTETKKVGAPLTAGGLIPILDNINLEDFSLLKGCSKVDVAAVIGVQDLLNSNCKTQVSCCKVGDTNQVGLVNANVDLKCAAQNII
What is the function of this protein?
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures.  Prevents recognition by the cellular immune defense system.
What are the official names of this protein?
Hydrophobin A.
What is the protein family that this protein belongs to?
Belongs to the fungal hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SAS10_DROME
Sequence: MDSDGDDYVMSGSDQEYDDEEREILEDLRKQRKKPHDPVQEVLGFSDDDDDDDDDDEEEQQDVAELMRDSDIEGAEDDDRDLPNTMDWGSKRSTYYNTDFVDQDYSSYNAQEEEQARAEEEEAKKIQLRLAKRMSEADFQLDNVEAAPAGSSDDNELSHITKVTSDLAGLSERERRQLMHSESPEFIILTQDFQQHLDEVKNLLKPVLNYVRKHDVPMVPALQYAGLCHTVLTTYCSNVAFYLLLKARRIDVKAHPVIRRLVQLKDLIEELKPRYEEYIRPQLEALLERIEDGDAFTVLDVAQRKAKLQILNKYNDGQQASVSSDDDDNDDDDDAESKEKDLQEEAGEEEEEEDARRGITYQMAKNKGLTPHRKKELRNPRVKHRGKYRKALIRRKGAVRTVRKELQRYGGELSGIKAGVTKSVKFRT
What is the function of this protein?
Essential for gene silencing: has a role in the structure of silenced chromatin.  May be involved in gene regulation during development.  Binds RNA.
What are the official names of this protein?
Something about silencing protein 10.
What is the protein family that this protein belongs to?
Belongs to the SAS10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EMTA_ECOUT
Sequence: MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQIKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DRT1_AGAAN
Sequence: MAFLKKSLFLVLFLGLVPLFLCENEKREGENEKEENDDQSEEKRSLGSFMKGVGKGLATVGKIVADQFGKLLEAGQG
What is the function of this protein?
Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria.  Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
What are the official names of this protein?
Dermatoxin-A1, DRT-A1, Dermaseptin AA-1-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermatoxin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YPV5A_METTF
Sequence: MRNGTLVLAALLTLFVLAGSSSAADVGIELDKNMSDGSPIKPTYNSTIKIKAIVKAWNLDVQNATARVQLPEGLVVQDYYMSQGYYDLETGTWEIGDIPAYEERSLTFICLLNRTGSVTVNANVTADGDDNSANNNAELTFKVFGISDLEVNVTGNKETARIGDTVRITVKLKNRGPHDANNIKIGNFLSGGLVVQNFSYDAGYFDDITREWIFETLAAGEEAKSKP
What are the official names of this protein?
Uncharacterized protein ORF5A.
What is the protein family that this protein belongs to?
To ORF5 in pFZ1.
Protein: XYL1_TRIKO
Sequence: MLSNARIIAAGCIAAGSLVAAGPCDIYSSGGTPCVAAHSTTRALFSAYTGPLYQVKRGSDGATTAISPLSSGVANAAAQDAFCAGTTCLITIIYDQSGRGNHLREAPPGGFSGPESNGYDNLASAIGAPVTLNGQKAYGVFVSPGTGYRNNAASGTAKGDAAEGMYAVLDGTHYNGACCFDYGNAETNSRDTGNGHMEAIYFGDSTVWGTGSGKGPWIMADLENGLFSGSSPGNNAGDPSISYRFVTAAIKGQPNQWAIRGGNAASGSLSTFYSGARPQVSGYNPMSKEGAIILGIGGDNSNGGQGTFYEGVMTSGYPSDATENSVQANIVAARYAVAPLTSGPALTVGSSISLRATTACCTTRYIAHSGSTVNTQVVSSSSATALKQQASWTVRAGLANNACFSFESQDTSGSYIRHSNFGLVLNANDGSKLFAEDATFCTQAGINGQGSSIRSWSYPTRYFRHYNNTLYIASNGGVHVFDATAAFNDDVSFVVSGGFA
What are the official names of this protein?
Arabinofuranosidase/B-xylosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 54 family.
Protein: CSCL1_MOUSE
Sequence: MTSSPFLDPWPSKAVFVRERLGLGERPNDSYCYNSAKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSEAGSEARFQRLSSSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSGDLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREARKETVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTYYTNLQAKTGRRTLINPKPCGQFCCCEVQGCEREDAISYYTRMNDSLLERITAEESRVQDQPLGMAFVTFREKSMATYILKDFNACKCQGLRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSETSIRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAAPILCLFWLFFFSFLRLGLTAPATLFTFLVVLLTILACLLYTCFGCFKHLSPWNYKTEESASDKGSEAEAHVPPPFTPYVPRILNGLASERTALSPQQQQTYGAIRNISGTLPGQPVAQDPSGTAAYAYQES
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel (PubMed:27045885).  Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion (PubMed:30382938).
What are the official names of this protein?
CSC1-like protein 1, Transmembrane protein 63A.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: PPBL_PSEAI
Sequence: MYKRSLIAASLSVAALVSAQAMAEINGGGATLPQQLYQEPGVLTAGFAAYIGAGSGNGKAAFLNNDYTKFVAGTTNKNVHWAGSDSKLSKTNETNPYLSAHGSAWGPLIQVPSVATSVALPFNKSGSNAVNFADVNTLCGVFSGRLTDWSQIPGSGRSGAITVAYRSESSGTTELFTRFLNASCSSALEGGTFAITTSFGNSFSGGLPAGAVSAQGSQAVMNTLNAAEGRITYMSPDFAAPTLAGLDDATKVAQVRGVSPAPANVSAAIGAVTPPTTAQRSDPNNWVPVFAATASATDPSVRPYPTTGYPILGFTNLIFSQCYADATQTQQVRDFFTRHYGASVNNDTAITNHRFVPLPASWKLAVRQSFLTSTNNLYIGHSNVCNGIGRPL
What is the function of this protein?
Has both a phosphomonoesterase and phosphodiesterase activity.
What are the official names of this protein?
Alkaline phosphatase L, L-AP, Low molecular weight phosphatase, Protein DING.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Secreted. Periplasm. Note=In strain MDR25 forms long appendages distinct from flagella or pili on the cell surface.
Protein: HEM3_XANCP
Sequence: MTTLRIATRKSPLALWQSEHVATALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLFLKELELAMLRGEADCAVHSLKDVPMELDAPFVLPAILERGDPADALVSNLYATLQALPLGARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEARITARLDAPEWLPAPAQGAVAVECRGDDARIHDLLAVLDAGRTRACVEAERAMNRALHGSCHVPVAAFARWEGEDLFLQGMVGSASDGRLIHAEAHGSPDATEDLGRLVADGLFEKGAAQLLAEL
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: P19_CNV
Sequence: MERAIQRSDAREQANSERWDGRCGGTITPFKLPDESPSLLEWRLHNSEESEDKDHPLGFKESWSFGKVVFKRYLRYDGTETSLHRTLGSWERNSVNDAASRFLGVSQIGCTYSIRFRGSCLTLSGGSRTLQRLIEMAIRTKRTMLQLTPCEVEGNVSRRRPQGSEAFENKESE
What is the function of this protein?
Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs).  Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
What are the official names of this protein?
RNA silencing suppressor p19, 19 kDa symptom severity modulator.
What is the protein family that this protein belongs to?
Belongs to the tombusvirus protein p19 family.
Protein: VTH1_YEAST
Sequence: MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPISEKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSGLMYVGREIYTTNDGVSFSQVKPSFGKIDGHISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTGSTIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIPYRSNENGDVPSKFYYSLDQGKTWGEYDLIMPIYPYRLVSTISDGSGSKFILTGTSITEDPIFITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICDKSKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPDGFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTLRTDLLGASNIPDALPARSASHESDLAAARSEDK
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.
What are the official names of this protein?
VPS10 homolog 1, Sortilin VTH1.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein.
Protein: WAAE_KLEPN
Sequence: MSNRLSVVMIAKNAADLLPDCLGSVSWADEIIVLDSGSTDNTVELARRLGAQVYTHTDWRGYGIQRQRAQDYATGDWVLMIDTDERVTPELRQAILKVLDAPQRGAIYSIARRNYFLGRFMRHSGWYPDRVLRLYERARYRYNDNLVHESLDSLGAEVIPLTGDLLHLTCRDFAGFQQKQLAYAAAWALERHQKGKKTSMAGIFSHTLGAFLKTLLLRGGVLDGKQGWLLAMVNAQYTFTKYTELWALSHGYSEKESS
What are the official names of this protein?
Lipopolysaccharide core biosynthesis glycosyltransferase WaaE.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. WaaE/KdtX subfamily.
Protein: DYN1_HUMAN
Sequence: MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAPPGVPSRSGQASPSRPESPRPPFDL
What is the function of this protein?
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.  Most probably involved in vesicular trafficking processes.  Involved in receptor-mediated endocytosis.
What are the official names of this protein?
Dynamin-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
Protein: RL23_GEOTN
Sequence: MKDPRDIIKRPIITENTMNLVGQRKYTFEVDVKANKTEVKDAVEKIFGVKVEKVNIMNYKGKFKRVGRYSGYTNRRRKAIVTLTPDSKEIELFEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CCA_NEIG1
Sequence: MQTYLVGGAVRDYLLGLPVKDRDWVVVGADAQTMLAQGFQPVGKDFPVFLHPKTHEEYALARTERKTAKGYAGFSFHADKDVTLEQDLMRRDLTINAMAQDADGKIIDPFGGQRDLAAGILRHVSPAFAEDPVRILRAARFAARYGFEIAEETIKLMRQMVENGEADALVAERVWQELAKGLMEKNPRKMIEMLRECGALQVLLPEVDALFGVPQRADYHPEIDSGIHTLMTLQRAADMGLSLPERYAALLHDLGKAKTPPDILPRHHGHDINGVEPVREVNQRLRAPRQCAELAELVCRWHIIFHQVGQLKSQTILNVLKKTDAFRRPERFQTALNVCIADTQGRLNREHTPYPQRAHWLALLEAANQADSGKIAAECRAQGKAHFIAEQIDRARLAQIAPLQKTFRGA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: DSC10_HUMAN
Sequence: MQIVQGFPADAPLCALMWTCSFLLPGLQTETPYPCTSLCLSSSQSAHPPLPVRVFSAESGYGIPFCAEPCSRVTVCHLQAVPVCMPV
What are the official names of this protein?
Down syndrome critical region protein 10.
Protein: CH60_CUPNH
Sequence: MAAKDVVFGDAARAKMVEGVNILANAVKVTLGPKGRNVVLERSFGGPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDNAGDGTTTATVLAQSIVREGMKFVAAGMNPMDLKRGIDKAVAAAVEELKKVSKPTTTSKEIAQVGAISANSDTSIGERIAEAMDKVGKEGVITVEDGKSLADELEVVEGMQFDRGYLSPYFINNPEKQVVQLDNPFVLLFDKKISNIRDLLPVLEQVAKAGRPLLIVAEDVEGEALATLVVNNIRGILKTAAVKAPGFGDRRKAMLEDIAILTGGTVIAEEIGLTLEKAGLNDLGQAKRIEIGKENTIIIDGAGDAAAIEGRVKQIRAQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVPGGGVALLRARAAISALTGENADQNAGIKIVLRAMEEPLRQIVLNAGEEASVVVAKVIEGKGNYGYNAASGEYGDLVEMGVLDPTKVTRTALQNAASVASLMLTTDCAVAESPKEESAPAMPGGMGGMGGMEGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.