PharMolix/UniProtQA huggingface dataset:
Protein: SURE_SALTI
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_NAUPA
Sequence: MKIDESLVKRLETLSMVEIEDKASMAKDLAEIVEFVEMLNELDTSNVDATFSTLDNSTYLREDEPIKNNVIEEILEHAPKAKDGFFIVPKIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: PUR7_ECOSE
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: DDX41_HUMAN
Sequence: MEESEPERKRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAEEEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDIGGERGCAFCGGLGHRITDCPKLEAMQTKQVSNIGRKDYLAHSSMDF
What is the function of this protein?
Probable ATP-dependent RNA helicase.  Is required during post-transcriptional gene expression.  May be involved in pre-mRNA splicing.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX41, DEAD box protein 41, DEAD box protein abstrakt homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX41 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CREN7_SULIA
Sequence: MSSGKKAVKVKTPAGKEAELVPEKVWALAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI
What is the function of this protein?
A probable chromatin protein, binds double-strand DNA without sequence specificity.  Constrains negative DNA supercoils.
What are the official names of this protein?
Chromatin protein Cren7.
What is the protein family that this protein belongs to?
Belongs to the Cren7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_ERYLH
Sequence: MHFLDQAKIYLKSGAGGPGAVSFRREKYIEYGGPDGGNGGKGGDIVFEAVQGLNTLIDFRYAQHFKAKRGAHGQGKDRTGAGAPDLVIKVPVGTQVLSEDKEEVLADFTEVGQRVTFLAGGMGGRGNASYKSSTNRAPRQHQPGQAGEEMWVWLRLKLLADVGLLGLPNAGKSTFINAVSNAKAKVGHYAFTTLVPKLGVVNHKGREFVLADIPGLIEGAAEGAGIGDRFLGHIERCRVLIHLVDISGEDPAEAFQTVNAELEAYGEGLEDKPQLVALNKLDLADEELVAGFAEELLEAGADEVFAVSGATGAGIEPLLDAVLGYLPDSTSTETKGSEVEEVDEEGGEWSPI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPB_SULIA
Sequence: MVWRQAKWDEPLIFELNNSGANRQGLLINKDDEIRSEIKEMKIPKNLLRENGPNLPSLSELEVVRHFIRLSQMNFGVDVGIMPLGSCTMKYNPKIEEKATAITESHHPLEDEDHVQGILEMIYELQNWFSEITGMDECSLQVPAGSAGEFAGVLMIKKYHEDHNRNYKDTMLVADTAHGTNPASAAMAGYKVMYVKSNGEGLVDMDILREIVNDKTAGFMLTNPNTLGLFEENILEISKIIHSANAILYYDGANLNGVLGIARPGDMGFDIVHLNLHKTFAVPHGGGGPGAGAICAKGELVNYLPYPMVEKVNGKYRLSKIPKNSVGKIATFYGNVGNLARSFAYLLGLGPQGVQMVGKMSTLATNYLIAKLRDIKELELIAPNRHRKHEVVFSVKQLMENYGVSANDVAKALLDSGFYAPTIYFPPIIEEALMIEPTETESKETLDMFAEALKKIVEDAKRNPEQLLKSPSNTSIARLDQAYANHPSTITPTYRVLKLRRMGKINYLK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: NDHH_LOTJA
Sequence: MNVPATRKDLMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNGPEQLGNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFREREFIYDLFEAATGMRMMHNFFRIGGVAADLPHGWIDKCFDFCNYFFTRVVEYQKLITRNPIFLERVEGVGVVGGEEVINWGLSGPMLRASGIQWDLRQVDNYECYEEFDWEVQWQKEGDSLARYLVRIGEMMESIKIIQQALEGIPGGPYENLEIRCFGREKEPEWNDFEYRFIGKKPSPTFELPKQELYVRVEAPKGELGIFLIGDQNGFPWRWKIRPPGFINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PITC1_XENTR
Sequence: MLLKEYRICMPLTVEEYRIGQLYMISKHSHEQSERGEGVEVVQNEPYEDPVHGQGQLTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDNIFESEAKDAEREICFVDIACDEIPERYYKESEDPKNFVSEKTGRGQLKEGWREAQEPIMCSYKLVAVKFEVWGLQSRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREYERTTQEATNRKIGVFPPAISISDITLPSHSHGGYSSAPSTPLATDAPEFLSVPKDRPRKKSAPETLTLPDPSQICLNVQPGAGNKPSLAKPE
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes (By similarity).  Binds PA derived from the phospholipase D signaling pathway and among the cellular PA species, preferably binds to the C16:0/16:1 and C16:1/18:1 PA species (By similarity).
What are the official names of this protein?
Cytoplasmic phosphatidylinositol transfer protein 1, Retinal degeneration B homolog beta, RdgBbeta.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class IIB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATNA_ARTSZ
Sequence: MATPFKVLIVGGGVAGLSLAIMLEAYGFDYELLEKHPDVAPKLGAGVGLTPNGARILDQIGVWDSMCEYASPVDAGIALSPTGNTVIFNPHMGEWLEKLFGYKIHFLSRHDCLRILFDKIKQKSNIHLRKEVTRISVGQPGEKAQVETKDGSTYIADLVIGADGVRSSVRNELWRIADTEKPGYIPNRDKSGIVSIYTAVIGIAHDPGLPRGGSARAYNHLRSYFTQEGVEGSGVFYWWLCTKNEEPIKGIVPKLSSDTKQTLLDKYADDQIGHGLTLGGLYKKSVYSAIIPLQEFVLEKCFYKNILLIGDTFRKLHPVAGQGANSAIEESALVADILWQLRENNALHDAAGMKQALTEFQEERFVRTTALREDANLVQRMESFDNLFMKFLSLHVIPRLPFVVAFLPQLGSAFTPARCMKYLPPPKAGMCPFSPDMQAKPNPRSPLATISWIVFLTLAACFPWSVHRLLPASSSSLPGFSEVFQLYTSVMAVSISGLWVIESYKASLLISPMFSSLPWILASNYWGWDKTLPVYLCFHVISSQHTVHYYTPQFMTDLGAAKALLPCLAMAYSIPGILTALASTDQTLSDWWPVAHCTFPVLVYVSSTFLRGMKAVPQGVEVVFSSVDLPYQRRFLTAIAVVSSAVHVTLIWNHGAALLNEGIISLLSVPLARTLASLTALIVAWGIYMTWEMRRIFATEVSLVKAWAVILVSTVLLGPAASLAGATYWSKVMLEKATSMQPLVQPTNGKS
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the meroterpenoids arthripenoids (PubMed:29797385).  The pathway begins with the HR-PKS atnH that catalyzes two chain-extension steps to form a reduced triketide, which then primes the SAT domain in the NR-PKS atnG to initiate three more cycles of extension to give a linear hexaketide corresponding to the polyketide part of arthripenoids (PubMed:29797385).  The FAD-dependent monooxygenase atnJ then performs an oxidative decarboxylation at C11 of the atnH/atnG product, via an electrophilic aromatic hydroxylation with concomitant ipso-decarboxylation (PubMed:29797385).  The membrane-bound polyprenyl transferase atnF then introduces a farnesyl group before the FAD-dependent monooxygenase atnK functions as the first epoxidase on terminal C12'-C13' olefin, followed by a second epoxidation on C7'-C8' catalyzed by atnA (PubMed:29797385).  The terpene cyclase/mutase atnI then initiates the sequential tricyclic ring formation through protonation of the terminal epoxide and catalyzes the regioselective and stereoselective 6/6/6-tricyclic ring formation (PubMed:29797385).  The cytochrome P450 monooxygenase atnM is responsible for hydroxylating both C1' and C10' (Probable).  The next steps may involve ketoreduction and acetyl transfer by the ketoreductase atnB and the acetyltransferase atnC, and lead to the production of arthripenoid B, the final biosynthetic product of the atn cluster (PubMed:29797385).  The hydroquinone moiety in arthripenoid B is prone to undergo spontaneous oxidation to afford a benzoquinone compound, a key intermediate for generating structure diversity (Probable).  For instance, addition of a cysteine followed by ring contraction gives arthripenoid A, tautomerization gives the main product arthripenoid C, addition of a molecular of water or amine affords arthripenoid D or E, respectively, and loss of one water forms arthripenoid F (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase atnA, Arthripenoid biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EF2_NEUCR
Sequence: MVNFTIDEIRALMDKPTNVRNMSVIAHVDHGKSTLTDSLLAKAGIISSGKAGEARATDTRADEQERGITIKSTAISLYGTLPDEEDIKDIVGQKTDGKDFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTVEGVCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQSFSRTIESVNVIISTYFDKSLGDVQVYPDRGTVAFGSGLHGWAFTIRQFATRYAKKFGVDRNKMMERLWGDNYFNPKTKKWTKNGTYEGKELERAFNQFILDPIFKIFSAVMNFKKDEVAALLEKLNLKLATDDREKEGKQLLKAVMKAFLPAADCLLEMMILHLPSPVTAQAYRAETLYEGPQDDEAAMAIKTCDPKGPLMLYVSKMVPTSDKGRFYAFGRVFAGTVRSGLKVRIQGPNYTPGKKEDLFIKAIQRTVLMMGGKVEPIDDMPAGNIVGLVGIDQFLLKSGTLTTSETAHNMKVMKFSVSPVVQRSVQVKNAQDLPKLVEGLKRLSKSDPCVLTFSNESGEHVVAGAGELHLEICLNDLENDHAGVPLTISDPVVQYRETVAGKSSMTALSKSPNKHNRLYMVAEPLEEDLCLAIEAGKITPRDDFKARARILADDFGWDVTDARKIWAFGPDTNGANLLVDQTKAVQYLNEIKDSVVSGFQWATREGPIGEEPMRSIRFNILDVTLHADAIHRGGGQIIPTARRVLYAATLLAEPSLLEPVFLVEIQVPEQAMGGVYGVLTRRRGHVFGEEQRPGTPLFTIKAYLPVMESFGFNGDLRAATSGQAFPQSVFDHWERLPGGSPLDSTSKVGQIVQEMRKRKGLKVEVPGYENYYDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2, Colonial temperature-sensitive 3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STAAM
Sequence: MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSVDAEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTNPMRILDCKVDRDKEAIKTAPRITDFLNEESKAYYEQVKAYLDDLGIPYIEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIELDIEENLDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_CHILA
Sequence: MTNTKGKRRGTRYMFSRPYRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: HRR1_SCHPO
Sequence: MEQVQDEIWKLSTLDAWEMVNKNTEVVFDEIPEPETLSEMKRHPLYSNIFNADNNTTSFTEQIETSETSKTQDSEGNKVDKNLKENKSIRRKRSIDNDYELSNVKRNDITSGKNREFENEHHPASDTSSWRELPSIPTLEELTSKSVELPSNNIYGGYKSFEDYLSIHYRLLREDAVSPLRESVLRYKVNPNYITGSSLAVYDHVRIDGYTISSSVIAAKLSFSVRAKKKIKWATSRRLISGSLVLLSNDDFQTFRIGTVCARPLSGLNKHPHEIDVKFEDISISLDPREEYVMIEATSGYWEAYKHVLRSLQRLSASTFPMKDYLVHCKSNQETAKHIQNNPRIRINSILKNNSQKIVNALEPFGPGEYILDSSQLKAYQSMLTKRLSIIQGPPGTGKSFVTLKAIETLLENTHSHVLPILVACQTNHAVDQILIRLLHQGASVMRLGSRTKDPEIAAVTIFQKAKHTKHSFKAAYNEIRHKKQRLIKQITNIMHNFNLEFVTLSYLHSKGIITTSQLESLRNNTEWISSVAENGEKTEEELISIWLGDAKVELITPSEITDGFEEELQIDPEKLEEIQKEAEDSGALMEEELRGKFINLRCKYLFSKLTTLHEKEIDTLLTIPNIWDIPEYSRGIIYCRWLESAYAAAEKELNRLYRFYLKVDRERIGFSNKRAAILLRGANVIGMTTTGLNKYRDILERINPKICFIEEAADVLEGPIIPAVFPSLEQLVLIGDHKQLRPGCSTYALRQDPFNLSISMFERLVENDMEYTRLTMQRRMHPQIRRLVSSVYEDLSDYEITKYWPSIPGMGEIRRFFLTHSRIEDNDGFASKINLFEAQMLVQFAVYLINNGVEPQKITCLTFYAAQKDLIERLLSESLNREKHFIKVATVDGYQGEENDVVLLSLVRNNDRTEVGFLSSPHRVCVSLSRARRGLFIFGNAQLVAESNPLWWDAINTLMNDETIQGLGDHLPLFTKDGTIYVNDPVELLDVNMRLTRK
What is the function of this protein?
Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation.  A member of the RNA-directed RNA polymerase complex (RDRC) which is involved in the generation of small interfering RNAs (siRNAs) and mediate their association with the RNA-induced transcriptional silencing (RITS) complex.  RITS acts as a priming complex for dsRNA synthesis at the site of non-coding centromeric RNA.
What are the official names of this protein?
Helicase required for RNAi-mediated heterochromatin assembly 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CHRB_DROPS
Sequence: MKMEVLSVQNHIQGKFGVNKIKDWPSSGVASTAPHPLEEEEENAVDVNAALDADVVDGHPASVLHMRQHQALNTRSTVPMAPPVAGSGKQSAVAASFDVVNGSSAAYHHAYMTNVLASTAHHPGHGHGPGPSPMPASPLQSTAGARFGAADNMDDVSASAVRDLSQQLQFQLRDAKQRHLACTEVNLPADLTERIAAEIIRMSDREPCGERACTLFIEFESEPNNVRRIASFKVDPDTVSIFELYLTLKQDKSGWTSLLPQFIKNLTRSNTINISPDFTLTKNKLYSSE
What is the function of this protein?
Inhibits cell growth by regulating the Tor pathway upstream of the Tsc1-Tsc2 complex and downstream of Akt1.  Acts as cell death activator during head development (By similarity).
What are the official names of this protein?
Protein charybde.
What is the protein family that this protein belongs to?
Belongs to the DDIT4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_BRUO2
Sequence: MARRGKKKGRPISGWVIFDKPKGMGSTEAVSKIKWLFSAEKAGHAGTLDPLASGMLPIALGEATKTVPYVMDGTKVYRFTVTWGEERSTDDLEGQPTKTSDKRPSREEVEALLPDYTGVISQVPPQFSAIKIDGERAYDLAREGETVEIPAREVEIDRLEIVGFPDADRTEFEVECSKGTYVRSLARDMGRDLGCYGHISDLRRVEVAPFTDEDMVTLAKLEAVWPPLPPKDEDGNVIEPAPRRDFSALDALVIDTGAALDCLPQVPLSDDQAQRVRLGNPVILRGRDAPLEADEACVTTRGKLLAIGYIEHGQFKPKRVFTAG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: MRAY_RICPR
Sequence: MLYNLLLPHIHNSHIANLFHYITFRSGLAIIITLSISFVTGPILIKFLRSLQKYGQPIRSDGPESHKTKAGTPTMGGIMIILSSCLSTLLLADLTNKYIWITLFGFISFGIIGFMDDYAKVKRNNHYGVRGKSKFLLQGIISLIIYVLLEYLDKNFSHLLNVPFFKNLSLDLNYFYMVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTAGSFALISYLVGNLIYANYLQLTYIPNTGELTVLCAGLVGSCLGFLWFNAQPAEVFMGDTGSLSLGGVLGIISVITKHEIVLAIIGGLFVIETTSVILQVYYFKATKGKRIFKMAPLHHHFEKHGWAESKVVIRFWIISVIFSLIGLSSLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TILS_LISIN
Sequence: MDDTKKRIHKYIEKHDLIRSDDKLLVAVSGGPDSFALLHFLWSANLVPKEAIAVAHLNHHLRENAEKEQLAVQTFCEERDIPFFIEEVDVKKRAEKLQKGIEETARIVRYDFFEKVMAENNINKLVLAHHADDQIETILMRLVRGSSSIGWSGIQPKREVRGGYAIRPFLPITKAEIIEYATKHALPYEIDESNTSQEYTRNRYRTQLLPFLSKENPAVYEHFKRFSEETSEDFQFLEELASNLLKKNLIQNGKQSTLLLSDFKNEANPLQRRAIHLLLMYLYNDDGRVITVNHIYQIIQMIQSENPSSSIDLPKKLTVIRSYNELHFQFGERHAPPEFYHQLELNDRIELDNKASIRLKLKSSVVQTNGLNGMLLDAEDITLPLIVRNRVNGDRMTMKGQAGSKKLKDIFIDAKIPRQERDNLPVITDYTGKILWVPGVKKSAYDREFSRSKKQYIIRYTRNIGGNESMHNDIQKVLISEDELQEKIRELGRELTAEYEGRNPLVVGVLKGATPFMTDLLKRIDTYLEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLIIEDIIDSGRTLSYLVDLIKYRKAKSVKLVTLLDKPAGRNVAIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGILKPEIYSE
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity).
What are the official names of this protein?
Bifunctional protein TilS/HprT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT6_DICDI
Sequence: MLITFVVDTSGSMSQKTTNGMTLLDCSKAAIEHFIKIRSKDASMRNDRFFLITSEENPITAVKIGWKDNFNSFIQEVKNLQTKDMSNLGFSLQKSFDFLNQFRVQSSIDNYGQGRNPWFIEPAIIILLTDGSSLTNSSSIIENFTLPKTQFHLNSDPTSEPFRWDQRLFSIVLKFGGISSNKSLPLPMEPAIAPMCDVTGGRCQVATNMKTMIQQVEGLMQKLQGGVVVSFEPLVNQQQAQAQAQQLLPPPPLSLHKMLYVRQQVGFWPIPEGYYPDITSLSLPMRLAHPVIRYSIIEADTHIPENFPFDKYELEPCPLTQYLLTNKIQCTHVFMMNSLQVSGQGEPFGCLRLNSAGNSVNLFVFPYNFPRLWILLEDLTTTFKMMPSQKWKQEFEGYLLSIPPYYINPLRGALKRFCSLNLIPDNIDSQFINFINNTIKKIKSQSISKMESERIINSKQQQQQQQQFSHQQQFQQFQQKQAQQYDSSPSSPSSSPSSSSSNTSGIGSSSGSGNLATKKKSFHQILDQGYSSDILSELIQQDNETSENSELSQELSESSTTGSSGGGSSSNINILQRNVFDIGRVQLLNQLDKMKDHIFKKKIQKDESKHHLPISQMGNYHETIGKRETLRDIDDDKKPNTPLFGNPYRKEKSNQRYMSIDEADEGGNLTSDGEGKNKLTPNKRRRLSGRGYPSLPTLNSLSNTSTTTSTTTTTTTTTPATSTNTTITSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTITSSPPTTSTNPLLQPTTASITTSTVPIPSTTVSSPITNTSIITTNIHIQPTQISSPPPLSSSLAINQPTQTSSVISSSSSPPPPPPPPPLPIVNNNNVIPSSLVQVTNNNNNIPTVPVNNISPPTSTISSPNNQHLLPTPPNINNTSISTTNVPNISTTTSNESIISQPISPTHKNIAGVVRPFRPNSPPLTIDTLTSSSSSSTIPTTTNGSLSTHDTPNTSPTLSSINYNNNNNNNNNNNNNNNNNNNNNNNNNNRKNSIITTTTPNNETNNIIKFVHKEIRRPTKDNHDIIIQQLSKLFSILSDGNLRLKLLKDTINLAKEYKKSSLISKLIGYIDQIK
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUP88_DANRE
Sequence: MASLAGDRWREALKNHDIFNNLQERLHLEPQGTSKRIAKNLTFCLNGDLFIWDSVESVFYTTNLRQLNSDGEPDTSRYQTLLCINPPLFEVCQVLVSPSQYHVALIGQRGATVLELPQRWGKKSEFEGGRIQINCKTIPVAERFFTSSASVTLRQAVWYPSETEEPHLVLLTSDNTIRFYNLKEPQSPARVLSVSQMDDDSSVHTRSRSYAASLGETAVAFDFGPLADSPHLSSLRMKAELVVYPLYILYGNGETFLNYISLSHSVGSLGKPMGPLPMYPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEAEEEEDGGAVERWSRGSETAPSLYVFECVELELTLKLPAGEEEEITESDFTCPIRLHRDPLCQHRYHCTHEAGVHSVGLTWFKKLHKFLESDEEDKDSLQELAAEQRCIVEHILCTRPLANSLPAPVRGFWIVSDLSLGATMICITSTYECLLLPLLSSIRPASPPLLCSHPGAGSDSSPLRGLAEDSFEQHIRNILARSSTNPLMLRSGDKDSSPPPSECLQLLSRATQVFREEYILKLGLAHEEMQRRVKLLSGQKNKQLEDLALCREDRKSLTEAAERLADKYEDAKYRQEAIMNRVKRVLGSLRSQLPVLSDSEKDMRKELQTINDQLRHLDNGIKQVNMKKDYQKKQMNAGASPAHSSLTLNAHQRKCLQGVLKEQGEHIAGMMKQIKDIKNHFSF
What is the function of this protein?
Component of the nuclear pore complex.
What are the official names of this protein?
Nucleoporin 88.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.