PharMolix/UniProtQA huggingface dataset:
Protein: YG4O_YEAST
Sequence: MYMIVVKYLYALCSSFFDCILNFNETVFGPSHRAFNPNNIIFIVDFQNFNILDSNMLVSHMTRHLSSWQYPTWVLVLTIRTTVSMHNRCTMRCSQTLESIPFHHTSKTFAFAD
What are the official names of this protein?
Uncharacterized protein YGR219W.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PGK_HYDS0
Sequence: MPNKKTIRDIDLKGKRVLVRVDFNVPIDNQGNIEDDARIRAAIPTIEYLLDAKAIVILMSHLGRPKGFDEKYSLKPVAKRLSRYIHKDVVMAPDCIGKDMENIVKNAKSEDVIMLENLRFHKEEEECDEEFSKKLASLGEVYVSDAFGTCHRKHASVYCVPQILKPACMGFLLEKELLYFEKAMVNPQRPVVAFLGGAKVSSKLNVIKNLLKRVDKMFIGGAMAFTFIKAMRYDTGKSLVENDLIDVAKDIIDISKKLGVKFYLPVDFIVGKELSDNTPIKTVLWQEIPQDYMGLDIGPVSISLAKELIGTAQTIVWNGPMGAFEYERFKDGTLEVARAIAHSQALSIAGGGDTDHAIIRAGVINAIDFVSTGGGAFLELLEGKELPCISVLDDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_WOLSU
Sequence: MKVKLADKHGFCFGVKRAIKLAESHQGGITLGPLIHNKKEIERLKNDFGVTVEESVENLPRGSEVIIRTHGIPKDDLAKLTQSAEKIIDATCPFVTKPQKICEIMSQEGYQIIIFGDINHPEVQGVMSYSSSEPIVVMSPKELFGAKLKEKVALVSQTTKKIEDFLGVASFLVQRCAEVRIFNTICNATFDNQEAARHLSQEVDIMIIAGGKNSSNTKQLLSICLEHCQDSYLIEDESELDPQWFTNKKTCGVTAGASTPEWIIERVVRTIEGYKG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: VPU_HV1Y2
Sequence: LQSLQVLAIVALVVATIIAIVVWTIVFIEYRKILRQRKIDRLINRITERAEDSGNESDGDQEELSALVERGHLAPWDVDDL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: HFLD_SERP5
Sequence: MAKNYYDITLAMAGISQTARLVQQLAHEGQCDREAFHTSLSSLLQMDPPSTLAVFGGEERNLKMGLETLMGVLNANNKGLAAELTRYTISLMVLERKLNANKQAMNQLGERLGQLERQLAHFDLESDTIISALAGIYVDVVSPLGPRIQVTGSPAILQNPQVQAKVRAALLAGIRAAVLWQQVGGSRLQLMFSRNRLFKQAQNIVAHC
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PA_I07A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVEPEDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCIENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKTTPRPIRLPNGPPCFQRSKFLLMDSLKLSIEDPNHEGEGIPLYDAIKCMRTFFGWKEPTVVKPHEKGINPNYLLSWKQVLEELQDIESEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDDCKDVSDLKQYDSDEPELRSFSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWERYCVLEIGDMLLRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENRSETWPIGESPEGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: EFTU_WOLSU
Sequence: MAKEKFVKNKPHVNIGTIGHVDHGKTTLSAAISAVLATKGLCELKDYDAIDNAPEERERGITIATSHIEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKEDMVDDAELLELVEMEVRELLSNYDFPGDDTPIVAGSALKALEEAKTGNVGEWGEKVLKLMAEVDRYIPTPERDVDKPFLMPVEDVFSIAGRGTVVTGRIERGVVKVGDEVEIVGIRNTQKTTVTGVEMFRKELDKGEAGDNVGVLLRGTKKEDVERGMVLCKIGSITPHTNFEGEVYVLSKEEGGRHTPFFNGYRPQFYVRTTDVTGSISLPEGVEMVMPGDNVKINVELIAPVALEEGTRFAIREGGRTVGAGVVTKITK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZFP11_MOUSE
Sequence: MSPENLSDCNNSVKDFDQHPELTIRQCVHREKPYKQEECDDSACDQHLRVHKGGMPYECKDCGKAFKYRSVLYQHRIIHTAARPYKCKECGKAFKRSRNLAQHQVTHKREKPHKCEECGRAFSALSVLTQHRITHTGEKPFKCKECGRAFKYNSTLTQHEVIHTEAKPYRCQECGKAFKRSHTLSQHQVIHKGEKPHKCDECGRAFSKHSSLTQHQVIHTGEKPYQCRECGKAFRYQSTLTRHHIVHTGAKPYKCPECDKAFNNSSTLSRHQIIHTGEKPYKCQECGRAFYCSSFLIQHMKIHFEEMPYRCRECGKPFRLSSQLIRHQRIHTGEEPYICRECGKTFKYQSNLTRHQILHTGAKPYKCPECGKAFNNSSTLTRHQIIHTGEKPYKCQECSKAFYCSSYLIQHMKIHFEEIPYRCKECGKPFKCSSQLIRHQRIHSGEKPYICKECGKAFNCTSYLTKHQRIHTGEKPYVCQECGKAFNCSSYLSKHQRIHIGDRLYKCKECGKAYYFSSQLNRHQRIHTGEKPYVCQECGKAFNCSSYLTKHQRIHIVEKPYVCKECSKAFSCSSYLTKHQRIHAGDRLYKCTECGKAYCFSSQLNRHQRIHTRERPYRCKECGKAFITSSCLKRHQETHTLQTPNSV
What are the official names of this protein?
Zinc finger protein 11, Zfp-11, Zinc finger protein Krox-6.1A/6.1B+/6.1B-.
What are the subcellular locations of this protein?
Nucleus.
Protein: FUMC_STAAN
Sequence: MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHQIDESIHPNDDVNESQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFESIIKIGRTHLQDATPIKLGQEISGWRYMLDRCEIMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAHYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2752_VIBC1
Sequence: MSDLISYDDVIDAAYDIFLEMAPDNLEPADVILFTAQFEDRGAAELVETGDDWVEHVGFDIDKEVYAEVRIGLVNEENDVLDDVFARMLISRDPEHKFCHMLWKRD
What are the official names of this protein?
UPF0263 protein VIBHAR_02752.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: SPON1_HUMAN
Sequence: MRLSPAPLKLSRTPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALRENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMNPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC
What is the function of this protein?
Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro.  May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity).  Major factor for vascular smooth muscle cell.
What are the official names of this protein?
Spondin-1, F-spondin, Vascular smooth muscle cell growth-promoting factor.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: VE6_HPV58
Sequence: MFQDAEEKPRTLHDLCQALETSVHEIELKCVECKKTLQRSEVYDFVFADLRIVYRDGNPFAVCKVCLRLLSKISEYRHYNYSLYGDTLEQTLKKCLNEILIRCIICQRPLCPQEKKRHVDLNKRFHNISGRWTGRCAVCWRPRRRQTQV
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation.  In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development.  The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT).  The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization.  Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis.  E6 also inhibits immune response by interacting with host IRF3 and TYK2.  These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: T1SC_MYCPN
Sequence: MEAPKHVNNACVIPNLTLKKMREIELDFPSKKIQEKIATILDTFTELSAELRERKKQYAFYRDYLLNQENIRKIYGANIPFETFQVKDICEIRRGRAITKAYIRNNPGENPVYSAATTNDGELGRIKDCDFDGEYITWTTNGYAGVVFYRNGKFNASQDCGVLKVKNKKICTKFLSFLLKIEAPKFVHNLASRPKLSQKVMAEIELSFPPLEIQEKIADILFAFEKLCNDLVEGIPAEVEMRKKQLDYYQNFLFNWVQEQKTQLEQIM
What is the function of this protein?
The specificity (S) subunit of a type I methyltransferase (MTase); this subunit dictates DNA sequence specificity.  The single R subunit has multiple frameshifts and is probably not expressed.
What are the official names of this protein?
Putative type I specificity subunit S.MpnORF365P, S protein, S.MpnORF365P, Putative type-1 restriction enzyme specificity subunit MPN_365, S.MpnORFCP.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: DEF_DESOH
Sequence: MTVLDIVTYPADVLKDGALPVANIDGKLQQLIDDMAQTMYAHQGVGLAAVQVDSGLRLVIYDVSDQREKQQFRVVINPEVVAVDGECVSEQEGCLSVPELRTDVKRAATVRVEGVDREGRPLVIDAEGLEAIVLQHEIDHLNGTLILDRASRLKRELYKRKVQKRIKQAWQET
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: Y4386_RHILO
Sequence: MPVRERPSMIVRPRPNFLQLFFIMRGSVVPRILPQIFGFAVYSAVILALARWFELDLGVFNITPFGLVGVTLSIYLSFRNNAAYDRWWEARKLWGTLVFEIRNLARATTSLIPDPAEQRALLMEALAFCHFLRGQLRKTDSIKDARAFIDAQAETVAGFANPADEMVRRMGRRANAQRRAGDVDPIGFRILDERLASITAIQAGCERIAGTPLPFAYTLLVHRTAYIVCLLLPIGLISTTGWATPLFTALIAYTFFGLDALSEELEDPFGTEANDLALDGLCRVCEISVFEALGEAPPKMLPAEKFYFS
What are the official names of this protein?
Voltage-dependent anion channel-forming protein mll4386.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARPC4_DICDI
Sequence: MSTAQVPYLNCIRNTLTASMCLQNFGSQIVERHNKPEVEVKTSKELVLNPVIIARNKNERVLIETSINSIRISVSIKKSDEVDVILAKKFVRFLQQRAENFIILRRKPVEGYDISFLVTNFHTENMFKHKLVDFIIQFMEDIDREISDLKLTLNARGRIVASEYLKNFA
What is the function of this protein?
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the pointed end of the daughter actin filament.  The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis.  In concert with a group of other proteins, the Arp2/3 complex plays a general role in the rapid activation and adaptation of the actin system to its multiple functions.
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 4, Arp2/3 complex 20 kDa subunit, p20-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Cytoplasm, cell cortex. Cell projection, pseudopodium.
Protein: DYR_MOUSE
Sequence: MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYEKKD
What is the function of this protein?
Key enzyme in folate metabolism.  Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (PubMed:25980602).  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (PubMed:25980602).  Binds its own mRNA.
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: WA22_MYCTU
Sequence: MSFVIAVPETIAAAATDLADLGSTIAGANAAAAANTTSLLAAGADEISAAIAALFGAHGRAYQAASAEAAAFHGRFVQALTTGGGAYAAAEAAAVTPLLNSINAPVLAATGRPLIGNGANGAPGTGANGGDAGWLIGNGGAGGSGAKGANGGAGGPGGAAGLFGNGGAGGAGGTATANNGIGGAGGAGGSAMLFGAGGAGGAGGAATSLVGGIGGTGGTGGNAGMLAGAAGAGGAGGFSFSTAGGAGGAGGAGGLFTTGGVGGAGGQGHTGGAGGAGGAGGLFGAGGMGGAGGFGDHGTLGTGGAGGDGGGGGLFGAGGDGGAGGSGLTTGGAAGNGGNAGTLSLGAAGGAGGTGGAGGTVFGGGKGGAGGAGGNAGMLFGSGGGGGTGGFGFAAGGQGGVGGSAGMLSGSGGSGGAGGSGGPAGTAAGGAGGAGGAPGLIGNGGNGGNGGESGGTGGVGGAGGNAVLIGNGGEGGIGALAGKSGFGGFGGLLLGADGYNAPESTSPWHNLQQDILSFINEPTEALTGRPLIGNGDSGTPGTGDDGGAGGWLFGNGGNGGAGAAGTNGSAGGAGGAGGILFGTGGAGGAGGVGTAGAGGAGGAGGSAFLIGSGGTGGVGGAATTTGGVGGAGGNAGLLIGAAGLGGCGGGAFTAGVTTGGAGGTGGAAGLFANGGAGGAGGTGSTAGGAGGAGGAGGLYAHGGTGGPGGNGGSTGAGGTGGAGGPGGLYGAGGSGGAGGHGGMAGGGGGVGGNAGSLTLNASGGAGGSGGSSLSGKAGAGGAGGSAGLFYGSGGAGGNGGYSLNGTGGDGGTGGAGQITGLRSGFGGAGGAGGASDTGAGGNGGAGGKAGLYGNGGDGGAGGDGATSGKGGAGGNAVVIGNGGNGGNAGKAGGTAGAGGAGGLVLGRDGQHGLT
What are the official names of this protein?
WAG22 antigen.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: METE_BORPD
Sequence: MTITHNLGFPRIGAQRELKRAVEAYWSGKKTAADLEETGRELRAAHWQRQAASGLQWVPVGDFAWYDHILEWTTLLGAVPARFGQPEGQPVSLDTLFRMGRGRAPSGTPTAACEMTKWFDTNYHYIVPELVPGQTFRIAREYLFEQVQEAQALGHQVKPVIPGPLTWLWQGKGDAYAGGASDAAKLQLLDTLLPVYAEVLARLARLGVEWVQIDEPILVLDLPQAWRDAFRTAYARLADAPVKLLVATYFGGLNDNLATALALPVAGLHVDLIRAPGQLQDVAAGLRPGQVLSAGIIDGRNIWRTDLDAALAALAPARQLLGERLWLAPSCSLLHVPVDLANETDLDAELRSWLSFAAQKLDELGLLGRALADARAPGVDEALAAQRAALRARRQSARIHNPAVGRRMAESNAVTRERAPFAERIARQQQLLKLPAFPTTTIGSFPQTAEIRALRRDWKSGALSDSAYEAAIRKEIESVIRFQEKIGLDVLVHGEPERNDMVEYFGELLAGFAFTRNGWVQSYGSRCVKPPIIFGDVARPAPMTVGWSSYAQSLTDKPVKGMLTGPVTILQWSFVRDDQPREQTCRQLALALRDEVVDLEQAGVRVIQIDEPAIREGLPLRRADWQAYLDWAVDCFRLSTAGVAADTQIHTHMCYSEFNDIIESIAAMDADVITIETSRSNMELLKAFEDFRYPNDIGPGVYDIHSPNVPDVDWMVGLMRKAAGRLPSERLWVNPDCGLKTRAWPETEAALVGMVEAARALRAG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: GNK1_GINBI
Sequence: ANTAFVSSAHNTQKIPAGAPFNRNLRAMLADLRQNAAFAG
What is the function of this protein?
Possesses antifungal activity against B. cinerea, M. arachidicola, F. oxysporum, R. solani and C. comatus and moderate antibacterial activity against S. aureus, P. aeruginosa and E. coli.  Inhibits HIV-1 reverse transcriptase and proliferation of murine splenocytes (PubMed:11118300).  Exerts antifungal activity through its carbohydrate-binding specificity (By similarity).
What are the official names of this protein?
Antifungal protein ginkbilobin-1, Ginkbilobin, GNL.
Protein: MDH_PSEPK
Sequence: MDVQGELAQGKALDVWQAAVDSGSDTHVHGGAKAEMLEGSELVVITAGVPRKPGQSRQDVLSTNLPILDSIMADIKHHAPTATVLVVSNPVDVLTYRAWSVSGQGRDKVFGQAGVLDTARMKCFIAEQTGFSARDITALVLGGHGDSMVPLMRYCQIGSVPLSHFLSSEQIEQIVERTRKGGGEILGLKKTGSACDAPGVAIAQMVDAIANGRNRILPAVAILEGEYGRTDIAMGVPCVLAEKGLARIIELPLDAQEQAMFDHSADQVARDIAEMKAL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Probable malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: RL1_FERNB
Sequence: MPKHSKRYNEIRKLVDSEKAYTLDEAVELLKKTATAKFDETVEFHIKTNIDYRKSEQNIRSTISLPHGTGKSVRVLVFAKGEKAEEAKQAGADYVGAEELADKIANEGFVDFDVAIATPDMMKVIGKLGKVLGPRGLMPNPKTGTVTEDIAAAVSEFKKGKVEVRTDKTGNLHFPVGKASFEPDKLKENIKSAYEQILSLRPAGVKGHFIKKAVVATTMGPGIKLDLNVLAEGKR
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TSX_KLEPN
Sequence: MKKTLLAAGAVVALSTTFAAGAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNDSQEQSTWYMGLGTDIDTGLPMSLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPLTDLWGGSLSYIGFTNFDWGSDLGDDNFYDLNGKHARTSNSIASSHILALNYAHWHYSIVARYFHNGGQWADDAKLNFGDGPFSVRSTGWGGYFVVGYNF
What is the function of this protein?
Functions as substrate-specific channel for nucleosides and deoxynucleosides.  Functions also in albicidin uptake and as receptor for colicin K.  Is also a receptor for several Tsx-specific bacteriophages.
What are the official names of this protein?
Nucleoside-specific channel-forming protein Tsx.
What is the protein family that this protein belongs to?
Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: VF423_ASFB7
Sequence: MLWRNEITEFMDQLSKYSQEILKTFKQLRPSEYKQYNEFLTQVTPLLQKTSEKIPELVDHIFNYLDNVEKICELLVNASSIIISSKIREQVKHGMSFSYKADLDSLADILSQKQYVLMHLSKNIAAEYFNTCLNQGKSKLDLKAASVFYSSRPRTASSAELYRKMLYAYGSPQEINYYTEKARNKTLDVEESDSMAIIERTARHNLSLMHPLEAMGLTFGATNTDADPEDLKDKTVINLTLPQATESITYHLKSLMQLKKVSTASGLNTNILKAFDNIISTPVKKNKMASKLAPGMDVVFTSDNGKTFFTKNILSKNMLAGPKERVFAYNNLISNLNNSCFIQNHNDFLRQQDSWPFYDAHNFTNKFLMQPIFSGQTRPRLQGAMEAAHVETHLTAFLQSIQPSRPQDPSVLASPKLSALILN
What are the official names of this protein?
Uncharacterized protein E423R, pE423R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus E423R family.
What are the subcellular locations of this protein?
Virion.
Protein: SODM2_STAAB
Sequence: MAFKLPNLPYAYDALEPYIDQRTMEFHHDKHHNTYVTKLNATVEGTELEHQSLADMIANLDKVPEAMRMSVRNNGGGHFNHSLFWEILSPNSEEKGGVIDDIKAQWGTLDEFKNEFANKATTLFGSGWTWLVVNNGKLEIVTTPNQDNPLTEGKTPILLFDVWEHAYYLKYQNKRPDYMTAFWNIVNWKKVDELYQAAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe] 2.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: PFKA_STRA3
Sequence: MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINQGYYGMVTGDIFPLDANSVGDTINRGGTFLRSARYPEFAELEGQLKGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGLPGTIDNDIVGTDYTIGFDTAVATAVENLDRLRDTSASHNRTFVVEVMGRNAGDIALWSGIAAGADQIIVPEEEFNIDEVVSNVRAGYAAGKHHQIIVLAEGVMSGDEFAKTMKAAGDDSDLRVTNLGHLLRGGSPTARDRVLASRMGAYAVQLLKEGRGGLAVGVHNEEMVESPILGLAEEGALFSLTDEGKIVVNNPHKADLRLAALNRDLANQSSK
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_BACTN
Sequence: MKTTLLVVGRTVEQHYITAINDYIQRTKRFITFDMEVIPELKNTKSLSMDQQKEKEGELILKALQPGDVIVLLDEHGKEMRSLEFADYMKRKMNTVNKRLVFVIGGPYGFSEKVYQVANEKISMSKMTFSHQMIRLIFVEQIYRAMTILNGGPYHHE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.