Protein: MDN1_GIAIN
Sequence: MSGYFTDLQNAEVLRAAESIVSSGQAVLLCGPSASGRTALLSHLASKLGAKPPIPLHLTTAQDTRDLIGSYVMTNKPGDFRFILGPLAYAAQSGRWISIEEITTISQDSLLLLSSVVNTRTLSVGSYQISVHPDFRIHAKTSADPALLSTIVKSMFYPLVLPPLGNHLFQVLTKHCNRGICTILAHIHVQFETHRLTAGRISASDMVKWARRIDLDLKNGGAVLNKAVQEASAGTAATTLVSWLDDNTRMVMIKNAWEAFVLRYSKEQTRRAFLDILRLSLNIHEELMLSTLLKIKVDIRHDYTQKRLVCGRVSLPFYESPDERSLDDICRTNHTTRLLEIISSAIRNNEPLLLVGPTGIGKTTCLQVIARALGKKLHVVNMSSQTDAADLLGGYVPATLDRILRNLYDAITGSLGLYISVRKNQIFVTELHKSYAEKDIAKFLANCETALSGMRQVLRKEVGEVVEQGSTEQRVSHDKKYARRGTYENSLYFLQSLGDTLEQATELHKILCHEVETKKPTMAFKYQEGLLVQALVKGDWILIDEINLASYDLLDVISQLVNPEHNEIAIPDKGFVAKNPHFRVFAAMNPGSDVGKKDLPPTIRRCFTEINVSEMSDDVDIVALTKSYLRMDDAMIEDRQGLDPNVVYQLFTVLKARAKTDLVTAAEAKSPCFSLRSLCRALSFAHRFRAAAGLRRSMYEGFMLAFGSMLNEKSRQAVHALILDKLLNGNKEYLLNPFIIQPFNKPCTAMIFQATTKDEAVTVEYQEPQAAHGFLEEEKSRARSTDYVLTKSTRSYMTTISRAIAAQLPILLEGTTSSGKTSLIKHIAKQFGCPITRINNHEHTDLSEYFGSYQPDPLTGQLVFKDGPLVTGMKQGHWVILDELNMASSEILEALNRLLDDNRELLVPDTQEIVRPAPGFLLFATQNPSGSYAGRKMLSEAFQNRFIMIEFADISTEELKEILINRSTSRHLAPQYCEKLITTIQAIKMQLSHRNNNAVMTNALITLRDLFRVADRLPRTLTELAMGIFELIGERQRDPADKQLVAEIIAKNLGLKTFSVSAAEQEYAIRVRPIQSMIEKALKAGADSPKSAFLLKFQDIVWTPSMIRLFALLFTSVSNGESPLLVGVSGAGKTTSVELIAAIMAQQLVQVNLHKHTESADFIGSLRPLRSRESMHAHLSVLKEYAATTTNVDKAVYAEIKRLETTLGTKLFEWEDGPILNCMKRGHILLLDEVSLADESVLERLNSVLETSRELTVAENPNMPRPVIAHTGFKLIATMNPAGDYGKKELSPAMRSRLTEFWMPHIRDINEVRMILTRKLQKTAIYRLGHQQGLDVVSLLADFFAEMDRITQSGRLGDVFTLSIRDILAVCDYITEVQTKEGTELGQMLIDAVTLSILDGLPVRTQLGNMPACREVKHEMVLYLANRILSANLTDIDLIQDLTVSISKDTNELTFLQASTQTVLATIPPGPQYNHAKALRKMTSFRLDAPTTIKNACRIAKALRFQRPILLEGDPGVGKSALVSAIAEICGYSLVRINLSEQTDLSDLLGSDLPAENGFRWVDGVLLKAVKEGAFILLDELNLANQTVLEGLNSLLDHRRSLFIPELMLSVKSPDTLRIFGTQNPRSQGSGRKGLPQSFINRFLNVYVDVLKSQDYDWILSNLFTDIPTYVLDYILGSTKQLRAGLEELKFGISGGPWELNVRDMMRLCDMLTTTPGLAQGITLAHAKHYAHILFGYRFRTADDDAYVQNVLFSPHSLDSVAEATQSHHWYSLRPLWNVTEDVVKIGSLAIPRIDPVFRDVLGTKLSYAHTSCFLTAQLVALEALAVAVTQNLSCILVGSPESGKSSILRTLADVVRQPLVHISASTATDVSDLIGAYEQVDVLYDLKSVIRDLCLFVHSLPIKASYSAISFSEFLKDLTASLDREIGDGLGSKSRAISMESIVSEVVQKLLLEFMAKFSPDLDSGGLAAKNFSLFCSEILTQDTTPVDERFSPHMPTIPELCKSMASLYLSTQQSQTGRFVWRDSELIRALERGYWVELTNANFCMPSVLDRLNSLLERGGGLEILEQGLEETRSIKVHPNFRLFISYAPTSDISRALRNRSLELSIDIQVSHYNLLDIVRCVYTSSTASGVSLDPYLIKLVSLVYFELSRDNPEIVGLGLLFKWLKLLVTYHKRFSTSVGDPKAVSSWVDRSFSSVFIASTLNADLHRQYMQVYQNARLALQGDGSLEACTLVEAAAVLNQLTLGAVRKLSISNSLQHSLALLELRTTVKPLDQLVSLADQEPQIMEPFSQVSGWLAICVGHSLDFQHHKELVSNLLTSTDINPMYLLTPPEPSSQALLKYISQGYLDMYSSPDSIIHQVIKYVSLCSPFYASILKLFIEGKFTTKDSYLLLYLIELSQHLATDPNNYDYVALFFSLFELLISHSIDPSTKTYSLGQRQVMRTFFDMILTDQYFESMPRLLSGYIRSLFISAARNDLETAWLAVRKNLALARISVHYLPELFKVFRYVIERLNLCISPEGVVFLQEGLSDSITASLWKDILATVIYMACRADDQTGDYVPKLAILQDSANRIDLCASKLSGNQHPTARALAQMQSLFLLFTGKAFCMQVSDTLEGWSQRDLTTQLPILLFRSMSFYHRNAAGPITYLRGPIFVSTGEFVTSSLSVPALLTNAIEEQATSVLKSLLCRSEDFLSYVGNVINSITTIVLRLFFAALEREAPSCDFTDGSFQLFALILETIVHSSNPLLASLTQGVEDILKAIISVQLSPSPLLLSGLVLTVASLVLYLLTSIANQRDPIVMTKHREVLYRRLAKLIATSIEDSKLHALFVFGDGALSESSSIYKELSTLYNSYAEAADQYAAELLVRADDEDNTFFEDLSSQLASLDGFEVHVLTFVSGVLNLEKVLQMHESTECIEAILDGLAVAERQISTTLAALLPRLINYTVESSYYLDMTIPIASFLMCLRVGLSAVISSVYAHVCDAINAARRLSSEGIGLQITLQDLLLLIQRVVVGTGDEFLDLLCYDKFIRSCCSSKTVSTLHVARLFTLSLLQYSSCSKGVQGDVSQFLLADTLRPERVSSIAAQFEIEEARSYRKYIADHSIFKTRNQSSTAEGVSEEDELKTQIAALFPKNDSHFIKSDTSSDDEQPISMSAQTKVDYDDAYATSFFTRMNMILIIGNCILHLYTSDTEALPIQERLQNLSSILQAHVPHLSRPLVALQAVTYALSICAGGVSSNLSIRSPLTPETDRLMYPLVTGATMGLVRVLSSRSPNVDYAKLQTGKTRRAIHCEDIYSRPYPYETAEFCSTLLRKIIVRTQHLLTEWPDNVQLLDIMHVCDKLMELPVLEAPLVMFLTGAEVLVRHLETWDKGAPAVYKYVTNPNVPVPESLTKSLIHLMVTWRRVELMSWNGFFSRVHTQFSNVSLTYWPELLIASLTYQRSVTQGEPSTEAYYAQMREFLYESNVGEFPVRLKLLYTLSALLSNIEELAEPELVSSPHKTMTSAVLFSIASEAVEFAKYMNKEFEEEAAQIKKRFEDQIRIFEWNERSSYTSWLTAQNSHRLCTKIIREYTEVLQHATRAFHMGYSATYDRIPLSVTVQEYLPLSSESGMLPPALSQELVERLNYCVEQMCHGRKESETLKRNEKNRLLSDVLDVLKETLGCVLSSGFAFKQSFGWKLAHLCLPSVHSTFELMHMFHDSLCQRCNEVEPHDIERMKRIIACLNQVFVQLSELVVELADIELLSRVMRTAPTGSSKSQADSVLYVYLADNSVPQLLTTQVMSHVTKAHKMCMSLQEFLIGLPLDSCKSSPTKLHEQIGGFLERFSADSVTALNRIKIFSKFSALIKRLCSITLIPLAFFEEAKAILQQILADLSPIFSALIAVLPTAPISTFVTEHAKYLAQVTEVIDTLTETAAQCRVEEAATVSSIEWPYFALPFASVGEEGLSVEIIVDNAKKQVSAYMTAFFTSTLQPILQCATRHVVSLPVLPQKLLCQIETLKGDMQALADVLAKFIGPLISGAIALLRTGFHCHVDDDQKETDNDNQSGLGLGDGTGDQNVSKEAAKELCEDDLMGNQNDRDQQEQQEKDGDDEAIEMQNDFGGMSESLHHDIEEEDSNGSDEEEVLEKEMGDEQGEAIDERNYNEDDDSAEEYSDEQKKNTNNNNDTMELAAQEKDQDSINSELSDPSGEQHEEQADATGSTDEQAQEDDYNDLDDKNLSGQSDLSVPEADGEDETVNEELEEEQQQMSDLSNPDQDACAIEEDDDRDLPSSDENAEEHDEHEAPVDIDDNEASDEQSTYNDNDRDDAINISAQQQATNDEEEMQKDTEYDQENITDSNPDANEVGTNDQKQTHEDNDQFRQENIEDQWEAESTENSQGEGAESADLKEGNPDMSLEEFQRIWKERLNIHDRESEKDEAAEPQDMPLQSNKTVEFDDSKSGRDGALGLTESKHRNLTNQEFDNPNEERNVEHNSSCETSQSSHDRPPAEHLNPEISDEGEESSTASDKQEQAVLSHMRESSKDLLNPEGEVYQELAVSLASEETKRAPEDVAAASARGNHLLLDLIKQTSAAAFSLAERLRIILEPTVTSDLKGDFRTGKKLNLRRIIPFIASEFQKDKIWLRRTKPSKRVYQVLLAVDDSSSMAPIAKYALQAITLLFNACKFLEVGQLSVFSFGQKFELLLPITDQYNDASLAYAIGSFTFAQNETRVSDAISIASDYLDSVRFFKGSDSALQLLLMISDGRLKEKGGVAREIRKCMGRGQLPVLIVLDTDKKSIMDIKSVSFITDSSGKRVRQTSMYLDDFPFQCYALLRHIEDLPETLVAVIKRWIESVSVYNAV
What is the function of this protein?
Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.  Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre-60S particles from the nucleolus and then driving late pre-60S particles from the nucleus.
What are the official names of this protein?
Midasin, Dynein-related AAA-ATPase MDN1, MIDAS-containing protein.
What is the protein family that this protein belongs to?
Belongs to the midasin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.