PharMolix/UniProtQA huggingface dataset:
Protein: ACTPN_ANTNG
Sequence: MKNRLVIIVFMVVTMLCASLALPLEEKEDEKDEKRSLEVAGAVMEGANLGMSVLQTILQAIGDVSRKIAVGVDNESGRSWTAQNAYFRSGTSDVILPHTVPSGKALLYDGQKNRGPVATGVVGVITYTMGDGNTLAVMFSVPYDYNWYSNWWNVKIYHGKVRASQKMYEDLYYYRSPFKGDNGWHERNLGYGLKSKGFMNSSGAALLQIKVMKA
What is the function of this protein?
Pore-forming protein that forms cation-selective hydrophilic pores in cell membranes and causes cytolysis (PubMed:30036605).  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers (By similarity).  This protein shows potent hemolytic activity (EC(50)=0. 09 nM), as well as potent cytotoxic activity on nucleated cells (L1210 cells) (PubMed:30036605).  The cytotoxic process starts with cellular swelling that is time and dose dependent and occurs up to a critical volume, probably due to influx of water via pores opened by this actinoporin (PubMed:30036605).  The second phase consists of the final loss of membrane integrity that leads to cytolysis (PubMed:30036605).
What are the official names of this protein?
Nigrelysin, Ng, Actinoporin, DELTA-actitoxin-Ani1a, DELTA-AITX-Ani1a, Pore-forming toxine, PFT.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
Protein: BCAR3_MACFA
Sequence: MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLTEHRPDAYQDVSIHGTLPRKKKGPPPIRSCDDFSHMGTLPHSKSPQQNSPVTQDSIQESPWQDRHCETFTFRDPHLLDPTLEYVKFSKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGISPGQAREGSLTEGRPDVTKRLSLTMGGVQAREQNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPCPNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKAPSSPSAWLNSEANYCELNPAFATGCGRGAKLPLCAQGSPTELLTAKQNGALGPRNSGINYLILDDDDRERPWEPAAAQTEKGQWDKGEFVAPLLETVSSFRPNDFKSKFLPPENKPLETAMLKRAKELFTNNDPKVIAQHILSMDCRVARILEVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERHSTMAIGIAVYILGCTGTLEDRAATLSKVIQVAVELKDSMGDLYSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPNNVSVPLLMPLVTLMERQAVTFEGTDMWEKNDQSCEIMLNHLATARLMAEATDSYRMNAERILAGFQPDEEMNEICKTEFQMRLLWGSKGAQVNQAERYEKFNQILTALSRKLEPPPVKQAEL
What is the function of this protein?
Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of actin fibers (By similarity).  Specifically involved in INS/insulin signaling pathway by mediating MAPK1/ERK2-MAPK3/ERK1 activation and DNA synthesis (By similarity).  Promotes insulin-mediated membrane ruffling (By similarity).  In response to vasoconstrictor peptide EDN1, involved in the activation of RAP1 downstream of PTK2B via interaction with phosphorylated BCAR1.  Inhibits cell migration and invasion via regulation of TGFB-mediated matrix digestion, actin filament rearrangement, and inhibition of invadopodia activity.  May inhibit TGFB-SMAD signaling, via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity).  Regulates EGF-induced DNA synthesis (By similarity).  Required for the maintenance of ocular lens morphology and structural integrity, potentially via regulation of focal adhesion complex signaling.  Acts upstream of PTPRA to regulate the localization of BCAR1 and PTPRA to focal adhesions, via regulation of SRC-mediated phosphorylation of PTPRA.  Positively regulates integrin-induced tyrosine phosphorylation of BCAR1.  Acts as a guanine nucleotide exchange factor (GEF) for small GTPases RALA, RAP1A and RRAS (By similarity).  However, in a contrasting study, lacks GEF activity towards RAP1 (By similarity).
What are the official names of this protein?
Breast cancer anti-estrogen resistance protein 3 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Localization to focal adhesions depends on interaction with PTPRA.
Protein: CRH2_CAEEL
Sequence: MNSSSSRSSMSMPMPMDMPQMHMGMNNNCEMNQMMHPIPNFPMKWEPCTPPDEKPHPSMLFPPLSGIFNQSRHSSTGEDYHGSSSGSPSSSLSSPNEFKDEPLGLDVHFGNSLFNAPFSPSATSSHSPSSYGMMHGSHSMASHQLHQQQLSPLPSVAHFSHSHHLQHHVVQHPSQASLQMNMNQIFSGPSHQYASSSVPHTFLFKDSTIYEGMGGMGLAAAQQQLKARNKMHEMAIRQHLITDQNITANGDLVLSAEERRTLVQEGYSIPQKYPLTKSEEESLKIVRRKIKNKLSAQESRRKRKEYIDALEGRLHCFSEENKSLKKQVHQLEASNRDLQQKLHQYESKEKM
What is the function of this protein?
Transcription factor (By similarity).  Plays a role in regulating the developmentally arrested larval state known as dauer, when induced by long-term exposure to the Gram-negative bacterium P. aeruginosa PAO1, but dispensable for dauer formation induced by starvation (PubMed:32963007).  Involved in regulating expression of microRNA mir-243, during long-term exposure to P. aeruginosa PAO1 (PubMed:32963007).
What are the official names of this protein?
CREB homolog crh-2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CALF_PENDC
Sequence: MSFKPLLLSLSLLSPALGVAPRQSASCRAIPGDPEWPSTSAWNALNNTVHGRLKATVPLPSVCHHEPFGTYNEDACTALKTEWLDDRTFLNNAAEVMNPGTQNYSCVPFTSPSQPCQLGNYASYSINVTGADDVIAGIRFARQKNIRLVIKNTGHDFAGKSTGTGALSLWTHHLNTTEIISSYESAEYTGPAAKLGAGVISGNVYQVVAEAGYRVMGGTCPTVGLAGGYTSGAGHSLLNGAYGMAADAVLEWEVVTAQGEHLIASQSNNTDLYWALSGGGPGTFAVVLSMTTKVFQDGPIGSGIMLFNLTSDNTEEYWGAIEDLWAFLPEFVDAGPNTWDFALTSTGFQAYAITVPDQNGTQVKSLLQPWLDSIEKRGIQYSYTPTDSPNYLQYFSSRFGPGIAGAGPATVQLASRLIPRAAMYNATQKKVIVSALRAFIEDGEDLELGCHALNVGNIEHPGNAVLPAWRNAIATCNVVNYWDWNITATEMQARKDLLVDRLIPGLEEATPGSGTYLNEIDARWKGDWITELYGDNYDRLLQIKNKYDPEHRFYAWTAVGSDSWFTDGSGRLCRV
What is the function of this protein?
Bifunctional decaline synthase; part of the gene cluster that mediates the biosynthesis of calbistrin A and related compounds.  Calbistrin A is a secondary metabolite with an interesting structure that was recently found to have bioactivity against leukemia cells.  It consists of two polyketides linked by an ester bond: a bicyclic decalin containing polyketide and a linear 12 carbon dioic acid structure (PubMed:30598828).  The polyketide synthase calA is probably responsible for forming the decalin moiety.  Because calA lacks a designated enoylreductase (ER) domain, the required activity is provided by the trans-enoyl reductase calK (PubMed:30598828).  Following release from the PKS, calF then probably catalyzes the oxidation and the subsequent Diels Alder cycloisomerization that lead to the formation of the decalin moiety (Probable).  The decalin polyketide backbone includes two C-methyl groups, at C7 and C11 in backbone, of which the C7 position is probably methylated by the methyltransferase domain of calA.  A candidate for adding the methyl group at C11, if not done by CalA, is the cluster methyltransferase calH (Probable).  Several additional tailoring enzymes within the cluster could be involved in the modification of the decalin polyketide product.  Those include the 3 cytochrome P450 monooxygenases CalE, CalG and CalL, of which one might be responsible for the introduction of the extra hydroxyl group attached to the backbone of the decalin moiety, at position C9 in the backbone, that allows for attachment of the linear moiety (Probable).  One tailoring enzyme activity that is expected to be involved in biosynthesis of calbistrin is an acyltransferase for connecting the two polyketide synthase products, and which could be performed by the cluster acyltransferase calJ (Probable).  The enzyme responsible for the biosynthesis of the linear moiety, probably a second PKS, has not been identified yet (Probable).
What are the official names of this protein?
Bifunctional decalin synthase calF, Calbistrin biosynthesis cluster protein E, FAD-dependent monooxygenase calF.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: ANS1B_RAT
Sequence: MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQFEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHPSQKSLQIATLLQDYLEGVGRSVVLEEEHAQEDTAQETRLSSPAQSPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHTISDHYLDNLSKISEEELGKNGSQSVRTSSTINLSPGEVEDEEEDPNSCGPTGLWEALTPCNGCRNLGFPMLAQESYPKKRNYPMEIVPSASLDTFPSENENFLCELVDTAVTKKPCSLEIARAPSPRTDNASEVAITAPGTGHHRNSSTGPTPDCSPPSPDTALKNIVKVIRPQPKQRTSIVSSLDFQRMNHNQEYFEISTSTGCTSFTSSPPVSPPTSSVETTEIKNEGAEHTDDLSQQEDDEPPKEYDAGQFAGLLHGSSPACEAPENPFHLYGKRNQGEDGQEEASLANSPLPFKQTPIENNPEPSVKKIKPKVVSRTIFHKRSHQLENHTIVGTRMSRGGSRNGDQWGVNPGGFVERACTLGRIRSLPKALIDMHLSKNVSKSDSDLIAYPSKDKARVNWSKSSTAERSSKDNSERTPSFTSEWEEIDKIMNSIDVGINSELEGMNGEATRPRCPVQTVGQWLESIGLPQYENHLTANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWELELINVLKISLIGHRKRILASLGDRLHEDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDAANKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVQIDPSEQKTLANLPWIVEPGQEAKRGINTKYETTIF
What is the function of this protein?
Isoform 3 can regulate global protein synthesis by altering nucleolar numbers.
What are the official names of this protein?
Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Amyloid-beta protein intracellular domain-associated protein 1, AIDA-1, E2A-PBX1-associated protein, EB-1.
What are the subcellular locations of this protein?
Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. SUBCELLULAR LOCATION: [Isoform 3]: Postsynaptic density. Cell projection, dendritic spine. Nucleus. Nucleus, Cajal body. Note=The synaptic localization requires DLG4 interaction. Translocation to the nucleus in response to stimulation of NMDA receptors (NMDARs) in a calcium-independent manner.
Protein: TYRO_ORYLA
Sequence: MKSLFLSAVLLQFFETCWSQFPRPCANSEGLRTKECCPVWSGDGSPCGALSGRGFCADVSVSDEPNGPQYPHSGIDDRERWPLAFFNRTCRCAGNYGGFNCGECRFGYWGSNCAEYRESVRRNIMSMSTTEQQKFISYLNLAKNTINPDYVITTGTRAEMGENGESPMFSDINTYDLFVWIHYYVSRDTFLGGPGNVWRDIDFAHESAAFLPWHRVYLLHWEQEIRKITGDFNFTIPYWDWRDAQSCEVCTDNLMGGRNALNPNLISPASVFSSWKVICTQQEEYNNQEALCNATAEGPLLRNPGNHDPNRVPRIPTTADVEFTISLPEYETGSMDRFANNSFRNVLEGFASPETGMAVQGQSTMHNALHVFMNGSMSSVQGSANDPIFLLHHAFIDSIFERWLRTHQPPRSIYPRTNAPIGHNDGYYMVPFLPLYRNGDYLLSNKALGYEYAYLLDPGQRFVQEFLTPYLQQAQQIWQWLLGAGILGALIATIVAAVIVFARRKRRRNQKRKRAPSFGERQPLLQSSSEEGSSSYQTTL
What is the function of this protein?
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.
What are the official names of this protein?
Tyrosinase, Monophenol monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Melanosome membrane; Single-pass type I membrane protein.
Protein: YRT7_CAEEL
Sequence: MTNNQNELGDVMDVLEDNIGYLTDRDREIPETDVAVIKYSAWWEIPVLETEDPLDFLTIGNNQCPASDDWDKLLNAELYDMPRRSQANSESTPPEHTWSGTSELGNYHYSYNDISIGMDAMSMNNRNRDDGFSSSSSSSQTSEGSEWLPEETEFKPKKVVTSEPLSPTPPETETRRLTKVQRRSMTDQEVEQRRKEANKKNSKNYNFNKKSKEAKLKEDLEKNHLYIERATAQEKQTLERIMECYTYFGDGNVLVIHQDAMQNFTEKEVFEEKLEQVDMDVARAREQSQELKSLKKLYQKHRQAYITATNDKALKKSKINTYGSRKSRALHSMNIAELELKKCILQFKIKKFERREKLLEEVENQIKQYFNFKESNHAGYMRLPQERQNRFEELCKTLKTSSPKTSIAGSHRRSTRSSEN
What are the official names of this protein?
Uncharacterized protein T07A5.7.
Protein: Y3766_MYCTU
Sequence: MTDTLFADVSEYQVPVNNSYPYRVLSIRVCDGTYRDRNFAHNYRWMRSAFDSGRLTFGIVYTYARPNWWANANTVRSMIDAAGGLHPRVALMLDVESGGNPPGDGSSWINRLYWNLADYAGSPVRIIGYANAYDFFNMWRVRPAGLRVIGAGYGSNPNLPGQVAHQYTDGSGYSPNLPQGAPPFGRCDMNSANGLTPQQFAAACGVTTTGGPLMALTDEEQTELLTKVREIWDQLRGPNGAGWPQLGQNEQGQDLTPVDAIAVIKNDVAAMLAE
What are the official names of this protein?
Uncharacterized protein Rv3766.
Protein: Y3977_RHIEC
Sequence: MDEKLSRVDPKLLELLVCPLSKGRLSYDREHNELVSEKAQLAYPIRDGIPIMLVSEARRLDE
What are the official names of this protein?
UPF0434 protein RHE_CH03977.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: RECO_METNO
Sequence: MQWSDEGLVLGARRHGETSVVLELMTAGHGRHLGLVHGGRSRRMQPVLQPGNRVRAVWRARLDEGLGHFAVEPIESAAGRLMGSRLALYGLAHAAALLRLLPERDPHPSLYAAAQVLVAHLTDPAIAPALMVRFELAVLADLGFGLDLSACAATGSNAYLAYVSPKSGRAVSAAAGEPWRDRLLALPDFLVAREAGGTGATPTPRDVRQGFTLTGYFLDQHVWHPRGVAPPEARELFVALGTADAG
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: AROB_BRUO2
Sequence: MNAPTTVADSVTVPVSLGDRSYDILIGKGLVERAGEEVAKRLKGVRVAIVTDENVAAVHLERLQASFARAGIDSTPVIVAPGEKSKSFATLETVTNAILAAKLERGDAVVALGGGVVGDLSGFVAGIVRRGMNFVQMPTSLLAQVDSSVGGKTGINTAHGKNLVGVFNQPQLVLADTQVLDTLSPREFRAGYAEVAKYGLIDRPDFFAWLEANWQEVFSGGAARTKAIAESCRSKAAVVARDERETGDRALLNLGHTFGHALESATGYDSSRLVHGEGVAIGMALAYRFSARMNLAGIEAAERVEAHLKAVGLPVSLAEVPGGLPPAEKLMDYIAQDKKVTRGTLTFILTHGIGQSFIAKDVPPAAVLEFLKERLAIA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZUP_ACHCY
Sequence: MEKTMLNAIKSGFGIAIAAMLVAAPAAAADFEVHMLNKGKDGAMVFEPASLKVAPGDTVTFIPTDKGHNVETIKGMIPDGAEAFKSKINENYKVTFTAPGVYGVKCTPHYGMGMVGVVQVGDAPANLEAVKGAKNPKKAQERLDAALAALGN
What is the function of this protein?
This soluble electron transfer copper protein is required for the inactivation of copper-containing nitrite reductase in the presence of oxygen.
What are the official names of this protein?
Pseudoazurin, Blue copper protein.
What are the subcellular locations of this protein?
Periplasm.
Protein: RBX1_HUMAN
Sequence: MAAAMDVDTPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
What is the function of this protein?
E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair (PubMed:10230407, PubMed:10579999, PubMed:15983046, PubMed:16678110, PubMed:19112177, PubMed:19679664, PubMed:23455478, PubMed:27565346, PubMed:29769719, PubMed:11961546, PubMed:22748924).  CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets (PubMed:27565346).  The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components.  As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation.  Recruits the E2 ubiquitin-conjugating enzyme CDC34 to the complex and brings it into close proximity to the substrate.  Probably also stimulates CDC34 autoubiquitination.  May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair.  Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M.  Involved in the ubiquitination of KEAP1, ENC1 and KLHL41.  In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM.  As part of a multisubunit complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A (PubMed:19920177).
What are the official names of this protein?
E3 ubiquitin-protein ligase RBX1, E3 ubiquitin-protein transferase RBX1, Protein ZYP, RING finger protein 75, RING-box protein 1, Rbx1, Regulator of cullins 1, ROC1.
What is the protein family that this protein belongs to?
Belongs to the RING-box family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PAFA_KRIFD
Sequence: MNRRIFGLENEYGVTCTFRGQRRLTPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATGECDSVTDLIAHDKAGERILEGLLVDAQKRLHDEGIFGDVYLFKNNTDSAGNSYGCHENYLVSRHGDFAKLADVLIPFLVTRQLICGAGKVLQTPRGAVYSVSQRAEHIWEGVSSATTRSRPIINTRDEPHADAERFRRLHVIVGDSNMSETTMLLKVASTDLVLRMIEAGIVMRDLTLDNPIRAIREISHDMTGRREVRLANGREASALDIQGEYLSKARDFVDRRELGTPAVERALSLWERTLKAIESGDLSGIEREIDWVIKYRLIERYRAQNNLGLASPRVAQLDLAYHDIHRPRGLYYLLERKGAVTRVVDDLRVFEAKSVPPQTTRARLRGEFIKRAQERRRDFTVDWVHLKLNDQAQRTVLCKDPFKSHDERVEKLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: Y9585_DICDI
Sequence: MDTIGLDETTTIEINNNSNNKHSSYSSSSSNNNSNNLIISKIPNKIIDSNNNKNNNNNKNNNNNNNKNNYYNINKSSKMDMDYLLDCVQKTHGLIKDLTDSMLISNDQEERKQFQKQLNESNNYLNELLSKLSYIKNNNNINNNNNNGNINSNNGTSFGEIKSIPLMSNETGFTNNKITNNFNYSENKNNNNNNNNGQEQHELFSTSNKIENNNNNNNNKINNENNNEKNKNNNNGQHIIPKIYISDHEMAPNSEFQNIDSISPSSQLICGESRLTPVSERNELTSPASSLPSLPSLPSSMPKENKENKEPINQQEEEEEEEEEDEQKKEEENNLVKMTTVQVENTQEKIPLAKSATISTTNKTIEIEEQEKGMDSEKLKKTIKSSSSSSSNLFNDFPKPFIPFVQSNYNTEERNEVLQIVKLIHYEYGVQIKDKTGQLDNYMYNINFNPPPQYMCNSNDINSNNINSNINNNNNNMSNNLKKKLLIISNEKRNKMGPQIQRSPEETYLSNHFDEEELSNYFSHSFMSPKIVKSPSSSNLNKINQNNQNNNNNNIINNNNNNNNQNNTTTNNKNKSNNEKNNDNNTVFNNNTTTTNNNNNNNNNNSSEKNKVIVFEKKEPGQFIFKKEKVAKLSTSLSYSNLSSSSSNGGTAEDEEYDRYYDSFHCVELVDEDLLVYDNEDIYFNDEVDQNKSPLISPSLSKSNTTTTTTTTTTTTTATYANVNANAIATIGSSRKINNTLSPNMNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNTSPTLTTQENNGISNGSGNGGRKIHYRSLSHGIIKTPFTNNKLKTLQIFVPTEPYTCRLEITIEENVTVERLLIEVIDLCIKERRKIQYHKRQKLQIQQLQLLQQPIITTTTTVAVQSNNNNNSSNNNNNNNNNNNNNMTSPINQSQSLTSSTTSSNISSSSSSNAFSPPTVSVSNQLISNNKNGNDFESLTFPFLIYTNHRDFILKKSDENGEIDQTLQPIIRTTEIKKLKTDCFSLVINPKAIRDTTHHPQIFRVHIIHSSNNINSNSNNNNNNNNNNNNNNNNNNNNYNNNNNNNCNNGIVKSISFSNIGEVDQSSSSIAPSSSTTAATAATSSTTKDSVAVVYKSSSTLASIKASICKKENLELNLCVFMTMSNEVIQNEKITLVELNLPSVKLVYDQIKPIQKSITPFQSEGVVGNAPRPITKLLGPIFFFTPDNICEIKQYVVSKIGKLGVKKDRYMEISKDKIMYSQFDYLPSSSVSQNGFHNNNNNNNKEYYGGGVGGGGGFTNYNNFSNANLNNNNNNSNFGNGNGNGGINGNNGNNSGSNNKENGGTGAGIGGGGGLQLPNNNNNNNTTPLKNNKFFRSFSSAVIKTPYQLINDISGVGIIINKPNSFYLKCNNKNSEYSSTDADEIVAKIQFIIRLKKENLI
What are the official names of this protein?
Putative uncharacterized protein DDB_G0267840.
Protein: ATPI_CARPA
Sequence: MDVISCSSNTLKGLYDISGVEVGQHLYWQIGGLQVHAQVLITSWVVIAILLGSAIIAVRNPQTIPTAGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGLTKKGLGYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARAB_SALSV
Sequence: MAIAIGLDFGSDSVRALAVDCATGDEIATSVEWYPRWQEGRYCDGPNNQFRHHPRDYMESMEAALKAVLAQLSAAQRANVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEADEITRLCHKPGKVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQAAVSWIELCDWVPALLSGTTRPQDIRRGRCSAGHKTLWHESWGGLPPASFFDELDPCINRHLRYPLFSETFTADLPVGTLCAEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNTLVKVIGTSTCDILIADKQSVGDRAVKGICGQVDGSVVPNFIGLEAGQSAFGDIYAWFSRVLSWPLEQLAAQHPELKTQINASQKQLLPALTDAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLVASTAFGARAIQECFTDQGIAVNNVMALGGIARKNQVIMQVCCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPAAQQSMASAVERTLRPRPEQAQRLEQLYRRYQQWALSAEQHYLPTAAPAPTTPANQAILTH
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: MDTG_ECOBW
Sequence: MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQVSN
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NPY_TYPNA
Sequence: MQGSMRLWLSVLTFTLSLLICLGTLADAYPSKPDNPGEDAPAEDMAKYYSALRHYINLITRQRYGKRSNPETMVSDVWWRESTENIPRSRFEDPSMW
What is the function of this protein?
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
What are the official names of this protein?
Pro-neuropeptide Y.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRP28_DEBHA
Sequence: MSKRPISVEELIGKSQSAEVISKPKFLSKSERQKLSLQRNQEIQDKKRQQSTVNNGAKKRYNNSIEDNPEPKKINKKLKKGRNFNFDWDEEEDTSNNYQPLVRYDNRTNPPDLGLSDMHWSEKQIDDMTTRDWRIFKEDYNITSKGGDIENPLRCWAESKLPAKLLNILIKNLGYDSPTPIQRASIPLALNGRDIVGIAETGSGKTLAFLLPLFSYILSVDSNYLLYEHQQESNFNKPLGLILAPTRELALQITKEAKLFGDKLNLNVVTIIGGHQYEETVHSVRNGVHIVVATPGRLIDSLERGIINLSNCYFFTMDEADKMIDMGFEKSLQSILNYLPASEKLETTIDGKIFNIKKRITLMFTATISPPIEKITKNYLMKPGYLFIGNVGEAVDNINQQFEYFGARQSSDEILDPKKLDKLFSILRFHKDENRNYSIIIFANFKKACEELAYELSRKGFSDNTVIHGSKSQEARERAIDSFREGKDKILIATDVAARGIDIPNVSLVVNYQMTKKFDEYIHRIGRTGRAGNKGTSCTFIDDGDSEVFLDLKKFLNKGKKKCPEWLLKHSSTQSQILRD
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KGUA_CLOTE
Sequence: MEKGLLIVISGPSGTGKGTVCKELLRNNNFWFSVSSTTRDPREGEIQGKSYYFMSKEEFEDKIKENDFLEYAKVYGNYYGTPKSKVIEMLDKGKDVILEIDIQGALQVKENYKEGIFIFILPPSMEELKNRIIKRGTETEESLMTRFKSAYKEINYVSKYNYAVVNDKVHDAVEKIQSIISAEKCRVDRIKDSILLSKEGIIHEQLYD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.