PharMolix/UniProtQA huggingface dataset:
Protein: FBX6_HUMAN
Sequence: MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAAQSPYRAVVQIF
What is the function of this protein?
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexes.  Involved in endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation.  Able to recognize and bind denatured glycoproteins, which are modified with not only high-mannose but also complex-type oligosaccharides.  Also recognizes sulfated glycans.  Also involved in DNA damage response by specifically recognizing activated CHEK1 (phosphorylated on 'Ser-345'), promoting its ubiquitination and degradation.  Ubiquitination of CHEK1 is required to insure that activated CHEK1 does not accumulate as cells progress through S phase, or when replication forks encounter transient impediments during normal DNA replication.
What are the official names of this protein?
F-box only protein 6, F-box protein that recognizes sugar chains 2, F-box/G-domain protein 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_THERP
Sequence: MPETIGVFVAWPYANGDLHLGHVAGVYIPADTFARYHRLRGNRVLMVSGSDAHGTPITVAAEREGVTPEDIFRRYHGRFLETYQQLGISFDLFTHTHTANHFRVAQDIFRTLYEKGYIFTQTQIQLYCEYDRRFLPDRYVEGTCPYCGYPNARGDQCDNCGRTLDAIDLIDPRCRLCGQRPLPRETEHFFFDLPAFTDRLLAYLERQTHWRPNVQHFVRNFIQDGLKPRPVSRDLEWGIPLPIPGYEHKVMYVWFEAVIGYLSASIEWSLAEGQPEVWQVWWRDPRARGYYFIGKDNIPFHAIIWPAELMGYDESLNLPYDIPANEFLNLEGQQFSTSRNWAIWVPDFLSRYAPDPLRDYLTSIAPETRDSEFTWQGFVERNNNELLATWGNLVHRILTFVQARFEGRVPEPGALDGRDHLLLDQIAAGFQRIGDLYARVELKAAQREAMALAREVNRYLDEKAPWFQIREDRAAAATTLFVALRAIDSLKLLLAPILPFTSEQLHRLLGYRDRLFGDIVIEPGPETGGHEVLRYRPAASEGRDRWAPSELEAGRPLPPPQPLYQKLEESVIEEERQRLLAQSR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_RICPU
Sequence: MARSIWKGPFVDGYLIKKVQKLMESGKSEMIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNEEMVGRKLGEFAPTRTFHGHGADKKIKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YG001_HUMAN
Sequence: MNNHRANDKFFLYVCMYVCIREKILLYKTHWMTPIFLKVVINTRRIKHHFKIHVPSQFFILITITKY
What are the official names of this protein?
Putative uncharacterized protein PRO1854.
Protein: INT12_HUMAN
Sequence: MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKISSTKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRLEKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPAVKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKTSSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPLKPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKTTSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (PubMed:16239144).  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).
What are the official names of this protein?
Integrator complex subunit 12, Int12, PHD finger protein 22.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOH_NEIMB
Sequence: MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVAYLTYFERKVIGFMQLRVGPNVTGPWGLIQPFADVFKLLFKEVTRPKLSNKALFYIGPIMSLAPSFAAWAVIPFNEEWVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGAMRASAQSISYEIAMSAALVCVVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIFIVYLISAVAETNRAPFDVAEGESEIVAGHHVEYSGFAFALFFLAEYIFMILIAALTSLMFLGGWLSPFPQSWGIVGTPSAFWMFAKMAAVLYWYLWIRATFPRYRYDQIMRLGWKVLIPIGFAYIVILGVWMISPLNLWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENO_STRR6
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL6_PARXL
Sequence: MSRVGKSPVALQGAEVALSDERITVKGPLGTISQAANSLVKVVNDNGTLKFEPVDESREANAMSGTMRALVANMVNGVTKGFERKLTLVGVGYRAQAQGDKLNLSLGFSHPVVHQMPEGIKAETPTQTEIVIKGINKQQVGQVAAEVRGYRPPEPYKGKGVRYANEVVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: COBS_SACS2
Sequence: MHLKEILAQFSFFTAIPVKSSASLEEIAESSYISPIIVGISLGLIESVAYLILYRILGELTGIVLLGIIELLRGFNHLDGLLDLGDALMIRGNREKKIKALKDVEVGSGGIGLLLVYLSIQIVALLKLDFSLYTIFYLISSNVLSMSLSLYILSTISPIPESNLGRIFHDKLKGKSTILLLELIPFISLYNVIVFIIFYMIMYKICGSLGGSSGDIAGASITLSFPLFLITDEITNLNYSLLSILCYLFSHLH
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLNE_YERPN
Sequence: MLPLPSELQIQAQSIKQRFSELPAPPDLRDEDIAVLALSDFVSDMLLIHPQWLEELHQQPPQPQEWQYYSQWLSQALAGVQDEAALLTALRLFRRRVMVRIAWSQVLQTSGTAETLQQLSTLAESMIIAARDWLYQVCCRELGTPCNRQGVPQPLLILGMGKLGGGELNFSSDIDLIFAYPENGQTQGGRRELDNAQFFTRLGQRLIKALDQHTIDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGGADDPYSQELRQMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFITQVFQLIRGGREPRLQERALLPTLQAVAELGLLPEQQVADLSGSYLFLRRLENLLQAIADEQTQTLPNDPLNQARLAWGMGYADWAAMSTALENHMQAVRVVFDDLIGDETPDIGEDPSHGLYKSLWQDVLEESDLAPLTPHLEEAARRQLLATISGFRHDVDKRTIGPRGREVLDQLMPRLFAEVCPRPDANVALSRLILLLLSIVTRTTYLELLVEYHAALKHVIRLCSASPMVASQLARYPLLLDELLDPQSLYQPLAPSAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQQLRIAAGDITEALPVMKVSDHLTYLAEAIIDAVIQQAWNQMVARYGQPSHLQQSEGRGFAVIGYGKLGGWELGYSSDLDLVFLLDCPLDVMTDGDRSIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGEAGMLVSTIEAFADYQRNEAWTWEHQALVRARIVYGSPKLHQQFDAIRQQILCRHREDPQLQQEVREMREKMRNHLGSKQRDIFDIKADAGGITDIEFIAQYLVLRYAASEPRLTRWSDNVRIFESMAHYDIMSPEEAAALTRAYVTMRDEIHHLALQEQSSKVAADSFIAEREQVAASWHKWLAANDANVS
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: FIXK_BRADU
Sequence: MKPSVVMIEPNGHFCSDCAIRTSAVCSSLDAAELREFEHLGRRVHFSSGETVFSEEDITTSFYNVLEGVMRLYKLLPDGRRQIVGFALPGDFLGMNLSGRHNFSADAIGAVTVCQFAKAPFGRFIEERPQLLRRINELAIRELSQARDHMVLLGRRSADEKVAAFLLGWRERLLALKGASDTVPLPMSRQDIADYLGLTIETVSRTFTKLERHGAIAIIHGGISLLDPARVEALAAA
What is the function of this protein?
B. japonicum has two FixLJ-dependent FixK homologs that are activators of the transcription of a group of genes involved in anaerobic processes such as denitrification and possibly nitrogen fixation.  FixK may bind DNA at the FNR consensus binding site.
What are the official names of this protein?
Nitrogen fixation regulation protein FixK.
Protein: Y362_HAEIN
Sequence: MRNSFKIMTALALGLFAMQANAKFKVVTTFTVIQDIAQNVAGNAATVESITKPGAEIHEYEPTPKDIVKAQSADLILWNGLNLERWFERFFQNVKDKPAVVVTEGIQPLSIYEGPYKDAPNPHAWMSPSNALIYIENIKNALVKYDPQNAAVYEKNAADYAQKIKQLDEPLRAKLAQIPEAQRWLVTSEGAFSYLAKDYNLKEGYLWPINAEQQGTPQQVRKVIDLVRKNNIPVVFSESTISAKPAQQVAKESGAKYGGVLYVDSLSAKNGPVPTYIDLLNVTVSTIVKGFGK
What is the function of this protein?
Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron.  Metal-binding component (Potential).
What are the official names of this protein?
Uncharacterized periplasmic iron-binding protein HI_0362.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS3_RHILW
Sequence: MGQKINPIGFRLGINRTWDSRWFADNAEYGQLLHEDLKMRKFVMSELKQAGISKVVIERPHKKCRVTIHSARPGLIIGRKGADIDKLRKKLSDMTNSETHLNIVEVRKPEVDATLVAQSIAQQLERRVAFRRAMKRAVQSAMRLGAEGIKITCAGRLGGAEIARTEWYREGRVPLHTLRADIDYGTAEAETAFGICGIKVWIFKGEILEHDPMASERRAMEGDAQGPASRDRDRDRDRRRDNA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DSBG_ECO57
Sequence: MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGMKGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRMEQSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESPATAAAILASKDPAKTWQEYEASGGKLKLNVPANVSTEQMKVLSDNEKLMDDLGANVTPAIYYMSKENTLQQAVGLPDQKTLNIIMGNK
What is the function of this protein?
Involved in disulfide bond formation.  Functions probably as a disulfide isomerase with a narrower substrate specificity than DsbC.  DsbG is maintained in a reduced state by DsbD.  In vitro, displays chaperone activity in both redox states (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbG.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbC subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: CYPC_STRCN
Sequence: MAGHTENEITIAAPVDLVWDMTNDLERWPELFSEYASCEVLSREANTVTFRLTMHPDENGKVWSWVSERTADREKLVVRARRVETGPFEYMNIVWEYEETPDGTRMHWTQDFAMKPDAPVDDAGMTDIINRNSPIQMALIRDRIEEVSCTTP
What are the official names of this protein?
Putative polyketide cyclase.
What is the protein family that this protein belongs to?
To polyketide cyclases.
Protein: RUVA_ECOLU
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CH60_CLOBL
Sequence: MAKSLLFGEQARRSMEAGVDKLADTVRVTLGPKGRNVVLDKKFGSPLITNDGVTIAREIELEDPYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVTAGANPIQIRTGIRKAVEKAVEEIKVISKPVNGKEDIARVAAISAASEEVGKLIADAMERVGNDGVITVEESKSMGTDLEVVEGMQFDRGYVSAYMVTDTEKMEAVLDDVYILITDKKISNIQEILPILEQIVQQGKKLLIISEDIEGEALSTLVLNKLRGTFTCVGVKAPGFGDRRKEMLQDIAILTGGEVISEELGRDLKDVTIDMLGTADSVKVTKENTTIVNGKGDKVAIKERVSQIRVQIEDTTSEFDKEKLQERLAKLAGGVAVIRVGAATETELKEEKLRIEDALAATKAAVEEGIVPGGGTAYIDIIPKIADLTSDIIDVKLGIDIIRKALEEPVRQIANNAGAEGSVIIEKVKATEAGVGYDALNDKYVDMLKTGIVDPTKVTRSALQNAASIASTFLTTEAAVADIPEKENTPPMAPGMGMDGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_GRABC
Sequence: MAAVELILLQRVEKLGQMGDLVRVKPGYARNFLLPGGRAIRATKANTERFEQQRAQLEAQNLKRREEAERIAERVSGLSVVIIRQAGESGGLYGSVSSRDIAVAITESGLSVNRQQIQLDQPIKMLGLTDVRVVLHPEVVLPVTVNVARSVEEAERQARGEAVGLAAEEAAAAAEAALIEVADEEEVEISA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GTPS3_THYVU
Sequence: MATLSMQVSTLSKQVKNLNTFGMGSASKLPMVARRVSTIRLRPICSASLQVEEKTRRSGNYQAPVWNNDFIQSFSTDKYKDEKFLKKKEELIAQVKILLNTKMEAVKQLELIEDLRNLGLTYYFEDEFKKILTSIYNEHKGFKNEQVGDLYFTSLAFRLLRLHGFDVSEDVFNFFKNEDGSDFKASLGENTKDVLELYEASFLIRVGEVTLEQARVFSTKILEKKVEEGIKDEKLLAWIQHSLALPLHWRIQRLEARWFLDAYKARKDMNPIIFELGKIDFHIIQETQLQEVQEVSQWWTNTNLAEKLPFVRDRIVECYFWALGLFEPHEYGYQRKMAAIIITFVTIIDDVYDVYGTLDELQLFTDAIRTWDFESISTLPYYMQVCYLALYTYASELAYDILKDQGFNSISYLQRSWLSLVEGFFQEAKWYYAGYTPTLAEYLENAKVSISSPTIISQVYFTLPNSTERTVVENVYGYHNILYLSGMILRLADDLGTTQFELKRGDVQKAIQCYMNDNNATEQEGTEHVKYLLREAWQEMNSAMADPDCPLSEDLVFAAANLGRASQFIYLDGDGHGVQHSEIHNQMGGLIFEPYV
What is the function of this protein?
Putative monoterpene synthase.
What are the official names of this protein?
Putative terpene synthase 3, chloroplastic, TvTPS3, Probably inactive gamma-terpinene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DAPB_METMP
Sequence: MVKVAVTGALGRMGSGIIKTITETDGLDVVAAIDIPNHPKKGQDVGELTGLGKIGVALSTSDELEAVLKESGAEVLVDFTAAAPCVQTAKTASKLGVNLVIGTTGFTPEQRAEMEDAISKNKVAATISQNYAVGVNIFFKTLELLAQKLGDYDIEILEMHHKFKKDAPSGTALRAAEIIQNNLNRDSNVIYGREGITGERTKEEICIHALRGGDIVGDHSVIFTTEGERLELSHRVTSRQSLVSGAVLAIKFVAQKKEGIYNTFDVLDLN
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_SYNS9
Sequence: MQFIDQARISTRGGRGGDGIAAFRREKYVPAGGPSGGDGGHGGHVVLEADSNLQTLLDFKYKRLFAADDGKRGGPNKRTGVSGRELVIKVPCGTEVRHLTTGILLGDLIEPGTRLVAAFGGRGGLGNAHYLSNRNRAPEKFTEGRDGEEWPLQLELKLLAEVGIIGLPNAGKSTLIAVLSAARPKIADYPFTTLIPNLGVVRRPSGDGTVFADIPGLIAGAAQGAGLGHDFLRHIERTRLLIHLVDAGSDDPVEDLRVVEQELKAYGHGLVDRPRLLVLNKKELVQESDLPGVLADLENASGRDVSCISAAMGTNLNELLENVWNELGV
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_ECOLU
Sequence: MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATLERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDHIPLAVISGPTFAKELAAGLPTAISLASTDQTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKDERSSH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXYT_PETMA
Sequence: CYIQNCPRG
What is the function of this protein?
Antidiuretic hormone.
What are the official names of this protein?
Vasotocin.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FPG_AERS4
Sequence: MPELPEVEVSRQGISPWLTGIKVTRVVVRDGRLRWPVPGEIQELVDLTIHRVSRRAKYLLLETDFGTADLHLGMSGSLRVLNIGTPAEKHDHVDIELANGKLLRLNDPRRFGALLWTREPAEAHALLAKLGPEPLTDAFNAEYLQGRAKGRSTAIKTFLMDNHVVVGVGNIYANEALYAAGIHPKRAAGNISAERLETLVAEIKRVLASAIQQGGTTLKDFTSADGKPGYFVQQLQVYGRGGQACFHCHTLLSEIRLGQRTTVFCSHCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: MURA_CHLPD
Sequence: MDKLVIHGGRRISGTVAASGSKNSSLPIIAATLLAEKGTFTLHRIPELHDIETFTQLLQHLGVETTFNNNTLRVSTENVQSILAPYELVKKMRASIYVLGPLLARFGEAKVSLPGGCAFGPRPIDLHLMAMEKLGAEIKIETGFITASVKGKKLRGAHIDFPVSSVGATGNALMAAVLAKGTTTITNAAAEPEIETLCHFLSAMGACIDGTGTTKLVIEGVATLQAIEFTNVFDRIEAATLLAAAAITGGSITLNGVEPSQLKAVLKKFVHAGCQISTQSDSVTLISPEQLLPTDVTAKPYPSFPTDMQAQWIALMTQASGKSLITDRVYHERFNHIPELNRLGAHIEIKNNQAVVHGPRKLSGTTVMSTDLRASASLVLAGLVAEGITEVLRVYHLDRGYEKIEMKLNALGAQISREKYKEFS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRA71_SHEEP
Sequence: MTRFFCCGSYFPGYPSYGTNFHRTFRATPLNCVVPLGSPLGYGCNGYSSLGYGFGGSSFSNLGCGYGGSFYRPWGSGSGFGYSTY
What is the function of this protein?
In the wool cortex, wool keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant wool shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of wool keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 7-1, HGT keratin, HGT-C2, High glycine-tyrosine keratin-associated protein 7.1.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 7 family.
Protein: PANB_CLOB8
Sequence: MKNTVLTFKQAKEEKRRLSMLTAYDYSMAKIIDESGVNGILIGDSLGMVIKGEDDTLAVTMDEIIYHTKAVKKGAKNALIVSDMPFLSYHVSIEQAVLNAGRLIKEGGANAVKLEGGANVAAQIKAIVDAQIPVMGHIGLTPQSVNAFGGFKVQGKSESAAKQLIDDAVLIEKAGAFSIVLEGIPEKVAELITNAVSIPTIGIGAGKYCDGQILVYQDMLGMFNDFVPKFVKQYANVGNVMREAISSYVKEVQAGDFPEEKHTFKIDENELKKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_HELPJ
Sequence: MFDANCLKLMFVAGSQDFYHIKGDRTNALLDTLELALQSKITAFQFRQKGDLALQDPVEIKRLALECQKLCKKYGTPFIINDEVRLALELKADGVHVGQEDMAIEEVVTLCQKRLFIGLSVNTLEQALKARHLDHIAYLGVGPIFPTPSKKDAKEVVGVNLLKKIHDSGVEKPLIAIGGITTDNASKLQKFSGIAVISAITQAKDKALAVEKLLKNA
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.