PharMolix/UniProtQA huggingface dataset:
Protein: KCNE3_RAT
Sequence: METSNGTETWYKSLHAVLKALNTTLHSHLLCRPGPGPGSGTGPDNQTEDHRASLPGRNDNSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKNRVSMI
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870).  Associated with KCNC4/Kv3. 4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells (By similarity).  Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship (PubMed:21911611).
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 3, MinK-related peptide 2, Minimum potassium ion channel-related peptide 2, Potassium channel subunit beta MiRP2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Perikaryon. Cell projection, dendrite. Membrane raft. Note=Colocalizes with KCNB1 at high- density somatodendritic clusters on the surface of hippocampal neurons.
Protein: TBCC_ARATH
Sequence: MEDDGQSSVAETLDPALQKKHHDMLERLSARHQARKSDSPDSSSSSSSTLESTSSFLAKFSDSKRSIESRIAESRLASSSTDSSKLKSDLAEISVAIDNLEKLLAENSYFLPSYEVRSSLKIVSDLKQSLDILSGELVPKKKFSFKSKSTTKKPESKLPEIQKPDVVLPPKLVPVRDSPGLRNKHGETLVKSFEGSSIGEFTLSDLDSCQVKLTGTVNALFLHRLKKCSVYTGPVIGSILIDDVEDCVLVLASHQIRIHCARKSDFYLRVRSRPIIEDSNGVRFAPYCLDYKGIDEDLKTAGLEEETNNWANVDDFRWLRAVQSPNWSLLPEEERVSLLTISGDS
What is the function of this protein?
Essential tubulin-folding protein involved in the final step of the tubulin folding pathway.  Required for continuous microtubule cytoskeleton organization, mitotic division, cytokinesis, and to couple cell cycle progression to cell division in embryos and endosperms.  Not essential for cell viability.  Binds probably to the multimeric supercomplex, stimulating GTP hydrolysis by the bound beta-tubulin and the release of the alpha-/beta-tubulin heterodimer.
What are the official names of this protein?
Tubulin-folding cofactor C, AtTFCC, TFC C, Protein PORCINO.
What is the protein family that this protein belongs to?
Belongs to the TBCC family.
Protein: GLPK_SALA4
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIVSVSQREFEQIYPKPGWVEHDPMEIWASQSSTLVEVLAKADISSDQIAAIGITNQRETAIVWERETGKPIYNAIVWQCRRTADICEQLKRDGLEDYIRDNTGLVVDPYFSGTKVKWILDHVEGSRERAKRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHDLDWDDKMLDVLDIPRAMLPQVRKSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPSGEVNYALEGAVFMAGASIQWLRDEMKLISDAFDSEYFATKVKDTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNSNHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGYWQNLDELQEKAVIEREFRPGIETTERNYRYSGWKKAVKRAMAWEDHDK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RSMA_HAEIG
Sequence: MNSKKHLGHTARKRFGQNFLHDTSVIQGIVAAIYPQPNQFLVEIGPGLGALTEPVGELVDHLTVVELDRDLAERLRHHPFLHQKLTVIETDAMQFDFGALYTKENLAEKGQKLRVFGNLPYNISTPLMFHLFKYHDVIQDMHFMLQKEVVKRLCAAPNSKAYGRLTIMAQYFCQVMPVLEVPPSAFKPAPKVDSAVVRLIPHKELPHPVKDLYWLNRVCSQAFNQRRKTLRNALSTLFSPENLTALGIDLNARAENLAIADYARLANWLADNPPADINKDEILDSEE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAE1_METAR
Sequence: MQCSRVLGIEGTAWSLSAAIVGWDKVYAEASHPYVPETGGIHPMAAAQHHASHVSQIVRQVLDSGYDFDGVAFSRGPGLGPCLRTVATAARALALAYDVPLMGVNHCVAHIEVGRWQTGCHDPVVLYVSGANSQVIAFRRGRYRVFGETLDIGIGNALDKFGRHLGLQHPGGPKIEALAREGKNYIHLPYVVKGMDLSYSGMMSAAKEAAAKYLKEDVCFSLQENAFAMLVEVTERALAHTGKNEVLIGGGVGANMRLQSMLDTMCRDRGAKFYAPPRKFFGDNGSMIAYTGLLQLKYDQTIPVEDSAVNPIYRTDEVEIPWL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHY_RHOCB
Sequence: MTDLPQAEGGCGAGNERLAAQAAAAGNAELMARFKADYPVGPHDKPQTMCPAFGALRVGLRMRRVATVLCGSACCVYGLSFISHFYGARRSVGYVPFDSETLVTGKLFEDVRASVHDLADPARYDAIVVINLCVPTASGVPLQLLPNEINGVRVVGIDVPGFGVPTHAEAKDVLSGAMLAYARQEVMAGPVPAPISGRSDRPTVTLLGEMFPADPMVIGAMLAPMGLAVGPTVPMRDWRELYAALDSKVVAAIHPFYTAAIRQFEAAGRAIVGSAPVGHDGTMEWLANIGRAYDVSPDKIAAAQNAFGPAIRGAIAGAPIKGRITVSGYEGSELLVARLLIESGAEVPYVGTAAPRTPWSAWDKDWLESRGVVVKYRASLEDDCAAMEGFEPDLAIGTTPLVQKAKALGIPALYFTNLISARPLMGPAGAGSLAQVMNAAMGNRERMGKMKAFFEGVGEGDTAGIWQDTPKLYPDFREQQRKKMEKAAKLAKAEEMI
What is the function of this protein?
Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.
What are the official names of this protein?
Chlorophyllide reductase 52.5 kDa chain, Chlorin reductase.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU5C_ORYSJ
Sequence: MEHTYQYAWVIPLLPLPVIMSMGFGLFLVPTATKNLRRIWAFPSVLLLSIAMVFSVHLSIQQINGSSIYQYLWSWTVNNDFSLEFGYLIDPLTSIMLILITTVGILVLIYSDDYMSHDEGYLRFFVYISFFNTSMLGLVTSSNLIQIYFFWELVGMCSYLLIGFWFTRPIAASACQKAFVTNRVGDFGLLLGILGFFWITGSLEFRDLFKIANNWIPNNEINSLLTILCAFLLFLGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLIARLLPLFISLPLIMSFISLIGTLTLFLGATLALAQRDIKRSLAYSTMSQLGYMMLALGIGSYQAALFHLITHAYSKALLFLGSGSVIHSMEPLVGYSPDKSQNMVLMGGLRKYIPITRTCFLWGTLSLCGIPPLACFWSKDEILSNSWLYSPFFGIIASFTAGLTAFYMFRIYLLTFDGYLRVHFQNYSSTKEDSLYSISLWGKRISKGVNRDFVLSTAKSGVSFFSQNLSKIHVNTGNRIGSFSTSLGTKNTFVYPHEPGNTMLFPLLILLLCTLFIGSIGIHFDNEIGELTILSKWLTPSINFFQESSNSSINSYEFITNAISSVSLAIFGLFIAYMFYGSAYSFFQNLDLINSFVKGGPKKYFFHQLKKKIYSWSYNRGYIDIFYTRTFTLGIRGLTELTQFFDKGVIDGITNGVGLASFCIGEEIKYVGGGRISSYLFFFLCYVSVFLFFFLS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DNAG_HALSA
Sequence: MEDTAKYLIHADFVVDGVVERSDVVGAAFGQTEGLLGDDLAIPDLQDSAKLGRIDVSVDSEGGQSFGDITIASSLDRVETATLAAALEAVERIGPCRADVEVDRIEDVRAAKRREVVDRAKELLATAFDEGAINADDILDEVRESVRVDDITDYDGYPAGPNVDSSDAVVIVEGRADVVTLLKYGIKNAVAVEGTNIPDAIAALSREKTATAFLDGDRGGDMILRELGQVGSLDFVARAPMGECVEDLSRRTVDSALRNKTPASAAAPIATTQSETAATDGSATPAPTPEPAPDTAPSPDSDGDDTEAAAPPTLAEHARAVADTETARLLDDALARIREVPAAEVVDAVADADSVPAVVVVDATITQRLLDVAAQRGVASLIGADTDEFVKQPLATRVRTLDDART
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: ARGB_SYNY3
Sequence: MSSTQDYIGEEAATRVKILSEALPYIQHFAGRTVVVKYGGAAMKDSNLKDKVIRDIVFMASVGIRPVVVHGGGPEINTWLDKVGIEPQFKDGLRVTDAATMDIVEMVLVGRVNKELVNLINQAGGKAVGLCGKDGQLMTARTMTNKDVGFVGEVSSVDARVVETLVKSGYIPVISSVAADEFGQAHNINADTCAGELAAALGAEKLILLTDTRGILRDYKDPSTLIHKLDIQQARELIGSGIVAGGMIPKVTCCVRSLAQGVRAAHILDGRLPHALLLEVFTDLGIGSMIVASGYDL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACOD1_RAT
Sequence: MPAHMLQEISSSYTTTTTITEPPSGNLQNGREKMKKVPLYLEEDIRPEMREDIHDPSYQDEEGPPPKLEYVWRNIILMALLHVGALYGITLIPSSKVYTLLWGIFYYLISALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFLHSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHAFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAVLARIKRTGDGSHKSS
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:2892838, PubMed:7947684).  Catalyzes the insertion of a cis double bond at the Delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:2892838, PubMed:7947684).  Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids.  Plays an important role in lipid biosynthesis.  Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity).  Plays an important role in body energy homeostasis (By similarity).  Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (PubMed:7947684).  Required for normal development of sebaceous glands.  Required for the biosynthesis of normal levels of Delta-9 unsaturated fatty acids and 1-alkyl-2,3-diacylglycerol in the Harderian gland.  Required for normal production of meibum, an oily material that prevents drying of the cornea (By similarity).
What are the official names of this protein?
Acyl-CoA desaturase 1, Delta(9)-desaturase 1, Delta-9 desaturase 1, Fatty acid desaturase 1, Stearoyl-CoA desaturase 1.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Protein: OAT_RAT
Sequence: MLSKLASLQTVAALRRGLRTSVASATSVATKKTEQGPPSSEYIFERESKYGAHNYHPLPVALERGKGIYMWDVEGRQYFDFLSAYGAVSQGHCHPKIIEAMKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYNKVLPMNTGVEAGETACKLARRWGYTVKGIQKYKAKIVFAVGNFWGRTLSAVSSSTDPTSYDGFGPFMPGFETIPYNDLPALERALQDPNVAAFMVEPIQGEAGVIVPDPGYLTGVRELCTRHQVLFIADEIQTGLARTGRWLAVDHENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRIAIAALEVLEEEHLAENADKMGAILRKELMKLPSDVVTAVRGKGLLNAIVIRETKDCDAWKVCLRLRDNGLLAKPTHGDIIRLAPPLVIKEDEIRESVEIINKTILSF
What is the function of this protein?
Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate.
What are the official names of this protein?
Ornithine aminotransferase, mitochondrial, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RNT_HAHCH
Sequence: MSESQNRPKSPLARRFRGFLPVVVDVETAGFNSKTDALLEVSAVIISMEDDGMLYPEPPVSFNVEPFAGANIEQAALEFTGIDPFNPLRDAKPEADALNELFRPIRKSVKSNGCNRAILVGHNATFDHSFLFAAAERGDVKRNPFHPFSTFDTATLAALAYGHTVLSRACQLAGIPFDNKEAHSAEYDAMKTAELFCSIVNRWKELGGWTTDQQDYAD
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: RIBA_SACD2
Sequence: MTVKYVESSKLPTPMGMFAMHGFSDDSSDKEHVVLTMGDVSSEEPVLVRIHSECLTGDALFSLRCDCGAQLQAAMHKIAIEGRGAIFYLRQEGRGIGLLNKIRAYKLQDCGADTVEANERLGFGADMRDYSILKPMFEHLGIAQVKLMTNNPRKIDALTQYGINIVNRIPHETGRNPHNADYLETKKGKLGHMFGEKDGE
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: RMLA1_SHIFL
Sequence: MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLMDTAVNRESGATVFAYHVNDPERYGVVEFDDNGTAISLEEKPQEPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMDQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAHRKGFIDAEQVKVLAEPLKKNAYGQYLLKMIKGY
What is the function of this protein?
Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.
What are the official names of this protein?
Glucose-1-phosphate thymidylyltransferase 1, dTDP-glucose pyrophosphorylase 1, dTDP-glucose synthase 1.
What is the protein family that this protein belongs to?
Belongs to the glucose-1-phosphate thymidylyltransferase family.
Protein: FOLD_SYNC1
Sequence: MSAQLLEGKVVAAAVLEDVARRVAVLKDKGISPGLGTILVGDDGPSVSYVNKKRETCKQVGIASFHNEIPASATQSDLLAAVRDFNDSPDVDAYIIQYPLPKGFDFNEALNLMLPEKDADGLHPVNLGRLVLQEPGPVPCTPAGIRAMLQHYDIAIEGKEVVVIGRGPTLGRPLSLLLTLKQPYANAAVTVVHSGIKDLGAYTRRADIVIAAAGCPGIVQPDMIRPGAVVISGGISWEGRKLLPDVDEAVGEVAGWITPRLGGVGPTTVAMLLLNTVQAAEERARRAGKL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SYY_THEMA
Sequence: MTPEEQVKILKRNVVDLISEEELLDRIKRKGKLRVKLGVDPSRPDLHLGHAVVLRKLREFQDLGHTVVLIIGDFTARIGDPSGRNETRPMLTKEEVLENAKTYQEQAFKILDPKRTELRFNGEWLDRMTFADVIILASKYTVARMLERDDFAKRFKEGIPIAISEFLYPLAQAYDSVAIQSDVELGGTDQLFNLLVGRKIQEEYGQEPQIVMTMPIIEGTDGKLKMSKSYGNYIAFNDPPEEMYGKLMSIPDELIIKYMRLLTDIPEERIEEYERKMKEKTINPRDVKMVLAYEITRFFHGEENAKKAQEHFVKVFQKKEIPDEMPVVEISQEKNIVDLLVEIGAASSKSEAKRLVSQGGVYIDGERIEDIKFTVEPDGERVLRVGKRKFYRISGGETKKL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SORCN_SCHJA
Sequence: MVMDTNSLRHIFSRVDADKSGSISANELQTSLSNGLGTPLNIRTVQLMVAMFDRDMNGTINFNEFLGLFKYVQDWQTCFRRYDRDNSGSIDLNEFSNALISFGYHLSPQFVNLMMRRFDRNRGSIAFDDFIYACVCLQTLTREFSRYDCRGIGHTVFSFEQFLTSAFAVII
What is the function of this protein?
Calcium-binding protein.
What are the official names of this protein?
Sorcin.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_ENT38
Sequence: MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLADSAMKMVRVQAIEKNRYRAEEMAEERILDVLIPPAKNNWGQNEQPQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMSPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESNGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQALTTDDFERILTEPNASITVQYKALMATEGVTIEFTADGIKRIAQAAWQVNETTENIGARRLHTVLERLVEDISYEASDLNGQSITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX133_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHRECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTGRCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1r, Toxin-like structure LSTX-A33.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_PARD8
Sequence: MGIRKLKPTTPGQRHKVIGAFDKITASTPEKSLVVGKKSTGGRNNTGKMTMRYIGGGHKQKYRIIDFKRNKDGIPATVKSIEYDPNRSSRIALLYYADGAKSYIIAPNGLEVGQTVVSGSDAAPEVGNTLPMANIPVGTIIHNIELRPGQGAKMVRSAGAFAQLTSKEGAYAIIKMPSGETRKILAACKATIGAVGNSDHALEKSGKAGRSRWLGRRPRNRGVVMNPVDHPMGGGEGRSSGGHPRSRNGLYAKGLKTRAPKKHSSKYIIERRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MFM2_PHOSM
Sequence: MAHTNTSTALHEQENFLPKNRLLLVILTLGTVLFVINIDHNGLSTLLPTIAEDLGAQKSITWAGSSQLIATTVFSVLYGRLSDIFGRKALFVSALGVFSIAELGCGFANSPRMLYAMRALTGASGGGIGNLSIIIATDVVSLRHRGQYMAVVAPFMVLGNVCGPLVAAGVAKSSLTWRGLFWLISPLGGLSAILAGYILPSTAPTDTFKQNLAKVDWLGSLTSTVAIVGFMVAVSGTGTYHPGYSPLAISLLSVSGAAFLAFLFIEWKFATLPIIPLTIFAIPDVSALLMQTFTLGWVNQANVYFIPIYAQNLRQWSPVISGVLLFPIIAVQVIVSMIAGRWMSKSGQYGTTIRLGVAFLLIGSLLETQFGRSTHPAYVVIVLLVIGIGVGAANQPMVIAMQAHTKKSERAVVTSSRNFFRFLGSACGVAMSAAILQSTLRASLPVAYKHLAESPYALAGLSPQERDVIAPSYERAIRHVFIASAGASVLCSLGLFVWKDDGYESRPNEDNDNDQHASTRETDEEDEQSTLIDNREPSAVSYGTVEAGERDRYKAPDRLRRGL
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS).
What are the official names of this protein?
MFS-type transporter M2, Squalestatin S1 biosynthesis cluster protein M2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATG12_MEDTR
Sequence: MAAAESPTSVRKVVVHLRATGDAPILKQSKFKIAGTDKFAKVIDFLRRQLHRESLFVYVNSAFSPNPDELVIDLYNNFGFDGKLVVNYACSMAWG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagy vesicles formation.  Conjugation with ATG5 through a ubiquitin-like conjugating system is essential for its function.  ATG12/ATG5 conjugate has an essential role in plant nutrient recycling (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINAL_PROMS
Sequence: MSPNSKGVEILSIGTELLLGNIINTNAQWISEQLSQLGLNHFRQSTVGDNCDRIVKVIQEISKRSNLLITTGGLGPTPDDLTTEAIAKSFNVNLFERPHLWDEIKQKLPNSKLQDDSSSLRKQCLFPKNAQIINNPRGTAPGMIWEPIEGFTILTFPGVPSEMKTMWEETACDFIKTKFSDNYSFFSNTLKFAGIGESSVAEKINDLLNLKNPTVAPYANLGEVKLRITARAKNHLEAKNIIQPVKEKLKKDFSKFIFGENDDTLPSVLIRELTERNQTIVFAESCTGGLLSSSLTSISGSSKVFKGSVVSYSNELKNSLLNISEEKLTKYGAVSEEVCESMAINAKEKLGADWAIAISGIAGPKGGSQDKPVGLVYISISGPNNHITNIKKLFNSTRNRVEIQTLSVNVCLNSLRLILLSNSK
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: LON_BUCAP
Sequence: MNSERSERIKIPVLPLRDVVVYPHMVIPLFVGRKKSIHCIETSMNNDKKIMLIAQKEASKDEPSTNDLFNIGTISSILQMLKLPDGTVKVLVEGLQRACIKNIESNGEHLVAEVELIISPTVIDKEQEVLIRTTVNQFESYIKLNKKIPSEILNTLSQTKNAEKLADTIAAHMPLKLADKQSVLEIYNVNERLEFLMAIMETEIDLLKVEKRIRNRVKKQMEKSQREYYLNEQIKAIQKELGDMDEIPDENKILKRKIKSLKMPKEAKEKTESELQKLKMMSPMSAEATVVRSYIDWMIQVPWNIKTKIKKDIQEAKKILDIDHFGLEKVKERILEYLAVQSRTNKVKGPILCLIGPPGVGKTSLGKSIAKSTGRKYVRMALGGIRDEAEIRGHRRTYIGSMPGKLMQKMVKAKVKNPLFLLDEIDKMSCDIRVDPASALLEVLDPEQNINFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEIIRLSGYTENEKLNIAKCYLYPKQMERNALKRNELIITDCAIISIIQYYTREAGVRSLEREISKICRKVVKLLILNKSLKKIEINSKNLKKFLGIKRFDYGKTNNLNQIGQVVGLAWTEVGGELLTIETACVSGKGKLTYTGSLGEVMQESIQAALTVVRSQAKKLGIKKDFHEKHDIHVHVPEGATPKDGPSAGIAMCTAIVSSLTKNPVKSNIAMTGEITLQGRVLTIGGLKEKLLAAHRGGVKTVLIPYENKRNLEEIPKNIIEGLTIYPVKNIEEVLKIALENTPYV
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK23_NEPOL
Sequence: MIIDLVKRPVITEKATRILEKNQYTFDVELSLTKPKIKALIEKAFKVEVVSVNTHRPPRRKRRLGTTQGYLPRYKRAIITLKRGFMIPLTPF
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.