PharMolix/UniProtQA huggingface dataset:
Protein: CHERP_HUMAN
Sequence: MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQEQHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDECK
What is the function of this protein?
Involved in calcium homeostasis, growth and proliferation.
What are the official names of this protein?
Calcium homeostasis endoplasmic reticulum protein, ERPROT 213-21, SR-related CTD-associated factor 6.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1.
Protein: HSF30_SOLPE
Sequence: MEDVMKVKVEEDGIPTAVLPMEGLHDVGPPPFLSKTYEMVEDSSTDQVISWSTTRNSFIVWDSHKFSTTLLPRFFKHSNFSSFIRQLNTYGFRKVDPDRWEFANEGFLGGQKHLLKTIKRRRNVGQSMNQQGSGACIEIGYYGMEEELERLKRDKNVLMTEIVKLRQQQQSTRNQIIAMGEKIETQERKQVQMMSFLAKIFSNPTFLQQYLDKQVHRKDKQRIEVGQKRRLTMTPSVTGSDQPMNYSSSLQESEAELASIEMLFSAAMDNESSSNVRPDSVVTANGTDMEPVADDIWEELLSEDLISGDRAAEEVVVVEQPEFDVEVEDLVVKTPEWGEELQDLVDQLGFL
What is the function of this protein?
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.
What are the official names of this protein?
Heat shock factor protein HSF30, Heat shock transcription factor 30, HSTF 30, Heat stress transcription factor.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HBHA_MYCTO
Sequence: MAENSNIDDIKAPLLAALGAADLALATVNELITNLRERAEETRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELRKAAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLVGIELPKKAAPAKKAAPAKKAAPAKKAAAKKAPAKKAAAKKVTQK
What is the function of this protein?
Required for extrapulmonary dissemination.  Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells (By similarity).
What are the official names of this protein?
Heparin-binding hemagglutinin, Adhesin.
What is the protein family that this protein belongs to?
To M.leprae HbhA.
What are the subcellular locations of this protein?
Cell surface.
Protein: Y2248_NITEU
Sequence: MPSFDIVSEVDKQEIRNAVDQLNKEVSTRFDFKGSDARAEQTDYELYLYADDEFKLGQVMDILMTKFTKREIDVRCLEKGQTEKISGNKVKQKVTVKTGVESDLAKKIIKLVKDSKLKVQASIQGEVVRVTGAKRDILQEAIQLVKGSITELPLQFRNFRD
What are the official names of this protein?
UPF0234 protein NE2248.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ATR2_STAC4
Sequence: MAVISLFRIIVDKWHVVLACSACLGALLFQALRRQSNSTKDVPFIGMELGSAEKRRKAYMTDARSLFRDGYQQFKDRVFGITTTSENLVVVVPPRFLDELGRLPDEVLSASMAVADISQDKYTKMEITDPIISHAVRGNLTMSLSRLNDAILEELRKALSLLLPTCDEWTSVNISEKLQRIVAVISGRVFVGPELCGSDAYLDAAIHIAHEASAAVQSISTLPPWKRPFLSARLPELRALRERQDKVHSVLRPVLEKRIQMNEEDRPDDMLTWIISSQKKHGERSIETMAKVQTALHLAAIGTTSEMATNAFYNLAAMPELVPELREEIRTVLEEHDGVVSTKSLQAMKKLDSFLKETARLYPPFLAAFERKVLRTFTLSNGQVIPAGALIKVPSQAIMTDPALFPDPDRFDAFRFYDLQQQKNILKDGSVSVGASVNQFVNSNKNSLVFGYGRHACPGRFLAADELKMILVYFLQAYEIRLEEGESRRYRNLEFAAFSIPDPTKTIQMKKLQ
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the core atranone cluster (CAC) which products are predicted to catalyze most or all steps of mycotoxin atranone synthesis, starting from geranylgeranyl pyrophosphate (GGPP) (PubMed:25015739).  The initial cyclization of GGPP to dolabellane is probably performed by the terpene cyclase ATR13 (PubMed:25015739).  The Baeyer-Villiger oxidation near the end of the atranone synthesis, which converts atranones D and E to atranones F and G is predicted to be catalyzed by the monooxygenase ATR8 (PubMed:25015739).  Of the CAC's other predicted gene products, the reducing PKS ATR6 might synthesize a polyketide chain (PubMed:25015739).  This polyketide is probably transferred onto the atranone backbone by the polyketide transferase ATR5 (By similarity).  Other predicted CAC products include 4 oxygenases (ATR2, ATR3, ATR4, and ATR14), 3 short-chain reductases (ATR7, ATR9, and ATR10), and a methyltransferase (ATR12) (PubMed:25015739).  These may all be involved in the various steps of atranone biosynthesis, although their specific roles must await experimental determination (PubMed:25015739).
What are the official names of this protein?
Cytochrome P450 monooxygenase ATR2, Core atranone cluster (CAC) protein 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: THIE_MYCS2
Sequence: MDQAVELPVQRLQRASLYLCTDARRERGDLAEFADAALAGGVDLIQLRDKGSAGEKQFGPLEARQELEALEILADAARRHGALLAVNDRADIALAAGADVLHLGQDDLPLDVARGIIGRRPVIGRSTHDAAQMAVAIEERVDYFCVGPCWPTPTKPGRPAPGLDLVRATAAHSPGKPWFAIGGIDQERLPEVLAAGARRVVVVRAITAADDPKAAAEDLKAAISAAG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: TXG1A_ETHRU
Sequence: MNTVSVVQFLAVGCAVFVLYGRGVFAAEGVKKAGQHKDAELCLGSDGLGHRLDEFWYNDDMCQRFLCFKDDEGIMYEQIANCPIAIAEGDCTLKPGTKGHYPDCCPAVECPPEDQKKRKFKRKCFLVNILTTLLTKLVKNLKKNQQ
What are the official names of this protein?
U-scoloptoxin(16)-Er1a, U-SLPTX(16)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAG_HUMAN
Sequence: MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPPVLFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK
What is the function of this protein?
Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity).  Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination.  Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2.  Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane (By similarity).  Negative regulator of neurite outgrowth; in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides.  In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides.  In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides.  Inhibits axon longitudinal growth (By similarity).  Inhibits axon outgrowth by binding to RTN4R (By similarity).  Preferentially binds to alpha-2,3-linked sialic acid.  Binds ganglioside Gt1b (By similarity).
What are the official names of this protein?
Myelin-associated glycoprotein, Siglec-4a.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft.
Protein: GBRA1_BOVIN
Sequence: MKKSPGLSDYLWAWTLFLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
What is the function of this protein?
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:3037384).  Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity).  The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity).  The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (By similarity).  GABRA1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection (By similarity).  Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-1, GABA(A) receptor subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
Protein: NEOR_STRCY
Sequence: MDPDAGVIFARTAAGAAVALGLLKCGRIWLCPVCSGQDPARPSEEITEAVVSWLQQGGWAYLVTFTARHTAADRLSDLMDALQGTRADAETGTKRRPGAYQRLITGAAWAGDKRRKSNQEGIRGRIGYIGMIRATEVTVGEGAGWHPHIHAIVLVGGRTEGQRGDKRITGTFTPSEDALTEWEDRWRRSGPATLARSTPGFRPPTGARSPGATAGARATASTSSSSVRSGRQRPGRVHRQDAGRQEPGPGAGTRRPQGRPPGQHDVLRTPSRIGDLMGGVPEEEAAGHGSLAWGLDRWAEYETAVSGAGHRVDPLPAPAPGPDRRRHRGRRHGRPVPDRRRRRFRDGVQIWDRAWKGLVGRSLDLAVVEAVEGREISMDALGELVQSAGQSRAFLRVLTPQEVTELYDELLRTLARRREQAAERRAAEAAEAEPTTR
What are the official names of this protein?
Neomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the Gram-positive plasmids replication protein type 1 family.
Protein: ISPDF_CAMC5
Sequence: MLDISLIMLGAGNSSRFELPVKKQWLRIGSDPLWLAATKNLSEFYTFKDIIVVSKECEYMARFAPHYKFVTGGDTRQQSLKNALNLVSSQFVLVSDIARPCITHELFSKIIEGSKQANCVVPALKIADTAYFGDEVIDRDKIKLIQTPQLSKTNLLKQALETDTLYTDDSSAMRAVGASVWHVLGDERAHKITTKSDLAKIPCLIPPSNEHFTGIGFDAHEFERGRELWLCGEKIEYEFGLKAHSDGDVALHALTDAILGAAGLGDIGELFPDTDAEFKGISSLLLLQEAYKKVQSVGFELVNADITIMAERPKISKFKRKMEANIAGALNLAPNRINVKATTTEKLGFVGRGEGIAVIASANLKYYDWTK
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: TDH_SOLUE
Sequence: MKALVKSKSQPGLWLEEIPEPAIGINDVLIRVLRTGICGTDVHIYKWDEWARETIHVPMAIGHEFVGRIEAVGSNVADFFPGDIVSGEGHVVCGRCRNCFAGRRHLCAKTMGVGVNRPGAFAEYIALPMTNIWRHHEGIDLDVAAIFDPFGNAVHTALSFPVLGEDVLITGAGPIGIMAAAVARHAAARYTVITDLNPYRLELAAKLGVTRAVNVREQKLGDVQKELGMTEGFDVGLEMSGNPAGFRDMLANMSHGAKIAMLGIPAGEMAIDWRTVIFNMLTIKGIYGREMYETWYKMSVMLQSGLDISPVITHRYHYTDFEKGFEVMSSGNSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROF_STRCO
Sequence: MTVNAKTSPSAGNTWRDLPAAQQPEYPDTEALRAVIADLESYPPLVFAGECDQLRARMAAVAKGEAFLLQGGDCAEAFDAVSADHIRNKLKTLLQMGAVLTYAASVPVVKVGRIAGQYSKPRSKPTETRDGVTLPTYRGDSVNGFDFTEAARIPDPERLKRMYHASASTLNLVRAFTTGGYADLRQVHAWNQDFVKSSPSGQRYEQLAREIDNALNFMRACGTDPAEFQTVEFFSSHEALLLDYESALTRVDSRTGQLYDVSGHMVWIGERTRQLDHAHIEFASRIRNPIGIKLGPSTTAEEALQYIERLDPEREPGRLTFIVRMGADKIRDKLPELVEKVTASGATVAWITDPMHGNTYEAASGHKTRRFDDVLDEVKGFFEVHKSLGTHPGGIHVELTGDDVTECVGGGDEIFVDDLHQRYETACDPRLNRSQSLDLAFLVAEMYRDQ
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-II DAHP synthase family.
Protein: PHAR4_MOUSE
Sequence: MEDPSEEAEQPSGDPGMGMDSVEAGDTTPPTKRKSKFSALGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGVLLEDPEQDGEDSGKLSHAALKNGHTTPIGSARSSSPVLVEEEPERSLRNLTPEEESKKRLGSTGSQPNSEAEPGPEHAPKQPLLPPKRPLSSSCEAKEVPAGSTARSVSSTSGSTTVTSAATTAATDMTKTVKSFVGPTPAPAPAPRTLPAAPASANTAATTTAPAKQPPIPPPKPAQRNSNPIIAELSQAMNSGTVLSKPSPPLPPKRGIPSTSIPSLEPAASFTTKTANDQREKTVSLCLEPPLIIPPSSPSPPLPTHIPPEPPRSPLVPAKTFQIVPEVEFSSSSDLFQDISQQEDQKTEVPKKIQDQSFGESHIPSRLPPLPLHIRIQQALTSPLPVTPPLEGTHRAHSLLFENSDSFSEDTGTLGRTRSLPITIEMLKVPDDEEEEQTCPFVEDVTSTSATPSLPLCLREEEKESDSDSEGPIKYRDEEEDDDDDESHQSALANRVKRKDTLAMKLSSRPSEPETNLNSWPRKSKEEWNEIRHQIGNTLIRRLSQRPTAEELEQRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAHDYDRRADKPWTKLTPADKAAIRKELNEFKSSEMEVHVDSKHFTRYHRP
What is the function of this protein?
Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development.  Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'.  During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina.  Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway.
What are the official names of this protein?
Phosphatase and actin regulator 4, Protein Humpty dumpty, Humdy.
What is the protein family that this protein belongs to?
Belongs to the phosphatase and actin regulator family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, lamellipodium.
Protein: DNAA_STRMK
Sequence: MDAWSRSLERLEAEFPPEDVHTWLKPLQADLRVDSLVLYAPNAFIVDQVRELYLARIRELLAHFAGFSDVFLEIGSRPRPVEAQNAPVSTPSAHVSSEPQVPFAGNLDNHYTFANFVEGRSNQLGLAAAFQAAQKPGDRAHNPLLLYGGTGLGKTHLMFAAGNAMRQANPGAKVLYLRSEQFFSAMIRALQEKTMDQFKRQFQQVDALLIDDIQFFAGKDRTQEEFFHTFNALFDGKQQIILTCDRYPREVEGLEARLKSRLAWGLSVAIEPPDFETRAAIVLAKARERGAEIPDDVAFLIAKKMRSNVRDLEGALNTLTARANFTGRAITTEFAQETLRDLLRAQQQAISIPNIQKTVADYYGLQIKDLLSKRRTRSLARPRQVAMALTKELTEHSLPEIGDAFAGRDHTTVLHACRQIRTLMETDGKLREDWDKLIRKLSE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRA_ECOLU
Sequence: MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDPADYALVWHPPVEMLAGRDLKAVFALGAGVDSILSKLKAHPEMLKPSVPLFRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWSGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLIEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWLHPRVAITPHVAAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STAES
Sequence: MIKMPRGTQDILPQDSAKWRYIENRLHTLMELYNYKEIRTPIFESTELFARGVGDSTDVVQKEMYTFKDKGDRSLTLRPEGTAAVVRSYIEHKMQGEPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSIDAEILAMVMHIYESFGLKHLKLVINSIGDSESRKEYNEALVKHFEPVIDTFCSDCQSRLHTNPMRILDCKIDRDKEAVKNAPRITDYLNNDSKSYYEQVKLHLDNLNISYVEDPNLVRGLDYYTHTAFELMIDNPEYDGAITTLCGGGRYNGLLQLLDGPDETGIGFALSIERLLMALDEEGISLDVSEDFDLFVVTMGEDADRYAVKLINDLRRNGIKVDKDYLNRKIKGQMKQADRLNAKYTVVIGDQELENNEIGVKNMISGESENVQLDELVNYFKSRKEV
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_STRP4
Sequence: MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTELDDQDRVLITEEA
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: PELO4_PELFU
Sequence: MLTLKKSMLLIFFLGTINFSLCEQERNADEEERRDEPEERDVEVQKRILPFLAGLFSKILGK
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Pelophylaxin-4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RR12_EPIVI
Sequence: MPTIKQLIRKKRQPNLNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGIEITAYIPGIGHNLQEHSSVLVRGGRVKDLPGVRYHIIRGTLDAVGVKDRQQGRSKYGVKIKNK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
Plastid 30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid.
Protein: GATB_RUEPO
Sequence: MLDLTFETPKPKTIAGAKHDWELVIGMEVHAQVASQAKLFSGASTAFGAEPNSNVSFVDAAMPGMLPVINEFCVEQAVRTGLGLKAEINLKSAFDRKNYFYPDLPQGYQISQLYHPIVGEGEVLVEMGDGTARRVRIERIHMEQDAGKSIHDMDPNMSFVDLNRTGVCLMEIVSRPDIRGPEEAAAYIAKLRQILRYLGTCDGNMQNGNLRADVNVSICRPGAYEKYQETQDFSHLGTRCEIKNMNSMRFIQAAIEYEARRQIAIVEAGGEVDQETRLYDPDKNETRSMRSKEEAHDYRYFPDPDLLPLEIEQAWVDDIAASLPELPDDKKARFIKEFGLTDYDASVLTAEVESARYFEEVAQGRNGKLAANWVINELFGRLKKEDHDITDSPVSPSQLGGIIDLIASDAISGKIAKDLFEIVYTEGGDPAEIVEARGMKQVTDTGAIEAALDEIIAANPAQVEKAKVNPKLAGWFVGQVMKATGGKANPGVVNQMVSKKLNG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: UBIA_ACISJ
Sequence: MSAVAPRSRLSLYLDLIRWNRPAGWLVLVWPTLAALWVAADGFPGWHLLAVFVAGTVLMRSAGCTINDIADRDFDRHVKRTTQRPITSGQLGVREAALVGVVLTLVAFVLVLTTRWEAVAWSVPAVLFTILYPFTKRFFAMPQAFLGIAFNFGIVIAFAAVQGRVPATAWVLWLANLFLVLAYDTEYAMVDRDDDLKIGMKTSAITLGRFDVAAIMGFFVLCLGLTAWVLAPYGLGWPLWLGLGVAAAQVAWHFTLIKDRTREGCFTAFSKSHWIGAAIFAGVALGYLLR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_LEGPH
Sequence: MIQMQTVLEVADNSGARKVMCIKVLGGSHRRYARVGDVIKVSVKDAIPRSKVKKGAVMRAVVVRTAQGVRRDDGSLIRFDDNAAVLLNNQNEPIGTRIFGPVTRELRERFMKIISLAAEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RUVB_ENTFA
Sequence: MTEEERLLSAASQEAEASIEKSLRPQFLAQYIGQDKVKQELTIYIEAAKNRNEALDHTLLYGPPGLGKTTMAMVIANEMNVNIRTTSGPAIERAGDLVAILNELEPGDVLFIDEIHRLPRVVEEMLYSAMEDFYIDIMVGQGTTAHPVHFPLPPFTLVGATTRAGMLSAPLRDRFGIISHMEYYQEQDLKEIVLRSADIFQTEIFEEGAFEIARRSRGTPRIANRLLKRVRDFAQVQSDGKIDRAIADKALTLLQVDHQGLDYVDQKLLKTMIDLYGGGPVGLSTLSVNIGEETETVEDMYEPYLIQKGFIKRTPRGRIATPFAYAHFGYDYLEGRKN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.