PharMolix/UniProtQA huggingface dataset:
Protein: DAPB_GEOUR
Sequence: MVKIAVCGAAGRMGGRIIAAISETEGAVVSGALERLGHPMVGQDAGFNAGLGAIGVTISDDLTAVVQGCDVLIDFTTPKVSLKNLEVCGLNKKSIVIGSTGFTPEERALAAELAKDIPVVLAPNMSVGVNVCFKVLADVAKILGDDFDVEIVEAHHKMKKDSPSGTAVRMGEVVAEALGRDYNKVANFHREGICGERTKDEIGMQTIRGGDIVGEHTVYFIGMGERIEITHRAHTRDMFSRGSVRAAKWVVSQKPGLYDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC44_CAEEL
Sequence: MRRSIRNLAENVEKCPYSPTSSPNTPPRTFSEIPGPREIPVIGNIGYFKYAVKSDAKTIENYNQHLEEMYKKYGKIVKENLGFGRKYVVHIFDPADVQTVLAADGKTPFIVPLQETTQKYREMKGMNPGLGNLNGPEWYRLRSSVQHAMMRPQSVQTYLPFSQIVSNDLVCHVADQQKRFGLVDMQKVAGRWSLESAGQILFEKSLGSLGNRSEWADGLIELNKKIFQLSAKMRLGLPIFRLFSTPSWRKMVDLEDQFYSEVDRLMDDALDKLKVNDSDSKDMRFASYLINRKELNRRDVKVILLSMFSDGLSTTAPMLIYNLYNLATHPEALKEIQKEIKEDPASSKLTFLRACIKETFRMFPIGTEVSRVTQKNLILSGYEVPAGTAVDINTNVLMRHEVLFSDSPREFKPQRWLEKSKEVHPFAYLPFGFGPRMCAGRRFAEQDLLTSLAKLCGNYDIRHRGDPITQIYETLLLPRGDCTFEFKKL
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Probable cytochrome P450 CYP44.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: OTC_METHJ
Sequence: MKKDFISILDISREELANLIAHARKLKEERRVGIQTPVLAHKTLGMIFEKSSTRTRISFEAGMFELGGHALFLNPKDMQLGRGEAIRDTARVMSRFVSAIMIRANRHDEVLELAAHADIPVINGLSDREHPCQILADIMTIEERLFRTEGVKVAWIGDGNNVCTSLILSTILTGMEVIVASPSEFAPGEDVVSEALRMGAKVRIVTDPREAATGADVVMTDTWISMGQEEEIDRRRQIFMPYQVNAELMACAKPGAIVMHCLPAHRNWEITDEVLDSKASAVWDQAENRLHAQKALLVRLLA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_THET2
Sequence: MKIYYEHDADLGFILGKKVAVLGFGSQGHAHALNLKDSGVDVRVGLRKGSRSWEKAEAAGLRVLPVAEAVREADVVMVLLPDEKQAQVYREEVEPNLKEGGALAFAHGFNVHFGQIKPRKDLDVWMVAPKGPGHLVRSEYQKGSGVPALVAVHQDASGSAFPTALAYAKAIGAARAGVIATTFKDETETDLFGEQAVLCGGLTRLIRAGFETLVEAGYPPEMAYFETVHEVKLIVDLIYEAGLKGMRYSISNTAEYGDYTRGDLAVPLEETKRRMREILRQIQSGEFAREWMLENQVGSPVLEANRKRWAAHPIEEVGSRLRAMMPFLKARVMEEVG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PRXD1_DANRE
Sequence: MDQSELVEAVSEAGGAAVAPVDLRKELEEFLKRLNIETTCIEHPEVFTVEEMMPHVSHLSGVVTKNLFLKDKKRRVFLVCVRHDRPLALGELSRRLGAPNLRLAEERLLLEKLRVRQGCVTPLALFLDTERSVTAVLDRELTHGGHTHIHCHPMTNSATMGITPADLLRFLEETQHTPVILSFD
What are the official names of this protein?
Prolyl-tRNA synthetase associated domain-containing protein 1, PrdX deacylase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRORSD1 family.
Protein: YEAO_ECOLI
Sequence: MNIQCKRVYDPAEQSDGYRILVDRLWPRGIKKTDLALDEWDKEITPSTELRKAFHGEVVDYATFREQYLAELAQHEQEGKRLADIAKKQPLTLLYSAKNTTQNHALVLADWLRSL
What are the official names of this protein?
Uncharacterized protein YeaO.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv3073c.
Protein: U84A3_ARATH
Sequence: MDPSRHTHVMLVSFPGQGHVNPLLRLGKLIASKGLLVTFVTTEKPWGKKMRQANKIQDGVLKPVGLGFIRFEFFSDGFADDDEKRFDFDAFRPHLEAVGKQEIKNLVKRYNKEPVTCLINNAFVPWVCDVAEELHIPSAVLWVQSCACLTAYYYYHHRLVKFPTKTEPDISVEIPCLPLLKHDEIPSFLHPSSPYTAFGDIILDQLKRFENHKSFYLFIDTFRELEKDIMDHMSQLCPQAIISPVGPLFKMAQTLSSDVKGDISEPASDCMEWLDSREPSSVVYISFGTIANLKQEQMEEIAHGVLSSGLSVLWVVRPPMEGTFVEPHVLPRELEEKGKIVEWCPQERVLAHPAIACFLSHCGWNSTMEALTAGVPVVCFPQWGDQVTDAVYLADVFKTGVRLGRGAAEEMIVSREVVAEKLLEATVGEKAVELRENARRWKAEAEAAVADGGSSDMNFKEFVDKLVTKHVTREDNGEH
What is the function of this protein?
UDP-glucosyltransferase that forms glucose esters with phenylpropanoids (PubMed:11042211, PubMed:11187886).  Glucosylates 4-coumarate, ferulate, caffeate, sinapate and cinnamate (PubMed:11042211, PubMed:11187886).
What are the official names of this protein?
UDP-glycosyltransferase 84A3, Hydroxycinnamate glucosyltransferase 3, AtHCAGT3.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: HPPD_BOVIN
Sequence: MTTYSDKGEKPERGRFLHFHSVTFWVGNAKQAASYYCSKLGFEPLAYKGLETGSREVVSHVVKQGQIVFVFSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIVREPWVEQDKLGKVKFAVLQTYGDTTHTLVEKMNYTGRFLPGFEAPPFMDPQLSKLPSCSLEIIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSVVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTKDIITAIRHLRERGVEFLAVPSTYYKQLREKLKMAKIRVKENIDILEELKILVDYDEKGYLLQIFTKPMQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQDLRGNLTDMEPNGVVSGM
What is the function of this protein?
Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
What are the official names of this protein?
4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvic acid oxidase, 4HPPD, HPD, HPPDase.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: WNT1_ALOVU
Sequence: SGSCTVKTCWMRLPTFRTVGNLLKERFDGASRVIYGNKGSNRASRADMRHLEPEDPAHKPHSPQDLVYFERSPNFCAANSKVGTAGTTGRACNNTSLGLDGCDLLCCGRGFRTLTERVTERCHCTF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.
What are the official names of this protein?
Protein Wnt-1.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: ATP61_BRASB
Sequence: MIDPIHQFHLNKIFTIGHIGNQEIAFTNSTAYMLLAVVLIAGMMLAAGRALVPGRFQSVVELSYEFVANTLRTSAGSHGMTFFPLVFSLFMFIFVSNIVGIIPYTFTVSSHIIVTFSLALLVFLTVIIYGFYKNGLKFFKLFVPSGIPAVILPLVVVIEIISFFSRPISHSVRLFANMLAGHVTLKVFASFVTMLGALGFVGKVGALLPLGLTVALTGLELMVAFLQAYVFTILTCIYLNDAIHPGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 1, ATP synthase F0 sector subunit a 1, F-ATPase subunit 6 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATK_DIOSP
Sequence: MDKLQRDGKEDTPRQRRFLYPLLFQEDLYAIAYDHYFNRSSSFEPMENSSSNDRFSFLTVKRLISRIRQQNGSIVPFVNCDQTKLVGHNRSFYSELVLGGLTAVPEVPLSIRSEHSLERMNEWTSFRSIHSILPLMEDKIPHSNFILDIRIPHLTHPEILVRTFRRWIQDAPSLHSLRSVLHEHRNLIISSNLDQLILIASKENTRLSLFLWNYYAYECESLLVPLWKRFFYSRSLPYESFIERTPFYRKIEHIVIFYHKYLKKSLWFLKDPSIHYVKHRERSIIALRGTYLLAKKWRYHITKFWQCHFHLWPQPYRIYIDELSNNCFSFLGYLLSVKMKTSVVRIKMPDDSFITDLITKEFDPIAPTTLLIGSLAKEKFCDISGHPISRLAWTGLTDDDILDRFDRIWRNIFHYHSGSSKKDGLYRMKYILRLPCAKTLACKHKSAIRVVRERFGSELFTKSSPKERESIFLSFSKTRSQRERIWHSDIIQINPLINSCRKKHNLQIEPLFDR
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSN5_YARLI
Sequence: MASLATFQVENDIVDVDSTPQQGFDRDDLYKYDDVEQKAILAAHPWRTDPSYFRNVLVSSIALVKMAMHARSGGAIEVMGMMTGKILPNTFVVMDCYPLPVEGTETRVNAQQEGIEFMVEYLQGLKDVGRRENIVGWYHSHPGYGCWLSGIDVDTQFQNQQFQEPFLAVVVDPNRTISAGKVEIGAFRTYPKDYKPPKKATKQNQDQSVPLSKAKDYGAHSERYYELDVSFFKSSLDENLLQLLWNKNWAATLSQSTIQLNHDYTSKLMLDLSEKNAQLAIGLGEKTPQSQGRGFREAMSKADNEPHTNLLNYSTKGQWEAVNRSVKDGVQIGSDELQGLMSLEIQRRLFGRAK
What is the function of this protein?
Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
What are the official names of this protein?
COP9 signalosome complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYL_BORRA
Sequence: MSKYDFKKIEKKWQNYWDKHKTYKVNEDPNVPKEKRIYILDMFPYPSANGLHVGHPEGYTATDILTRYKLLNGFNVLHPMGFDSFGLPAENYAIQTGKHPKKITEKNIEKFKEQIKALGFAYDWDREIKTHDVNYYKWTQWIFLQLYKKGLAYTKEIPVWYCPDLGTVLANEEVIQTPDGPRSERGFHKVERKPLRQWLLKITKYAERLIRDLEEVDWPDSVKEMQKNWIGKSTGVEIEFLIKESKEKIKVFTTRPDTIFGVTYLVLAPEHPMVDKITKDELKPIISKYKDKEILKSDLERTSLEKDKTGIFTGAYAINPITKEEIPIWIGSYILGTYGTGAVMSVPAHDERDFEFAKKYNLPIKQVVSQTGTNEVLIKPFTENGISINTPTEFNNLKTIEVKTKVIKWLIENKMGQEKVNYKLRDWIFSRQRYWGEPIPILFDDNLNEIPLNDDELPLTLPDIENYKPSGTGESPLSKIKDWVNVKRNGKIYKRETNTMPQWAGSCWYYIRYLDPHNEKEFANKEKINYWMPVDLYIGGAEHSVLHLLYARFWHKVLYDLGYVNIKEPFRKLINQGMITSFAYQDENGILIPNDEVEKKDNKFFSKKNNKELKQIIAKMSKSLKNIINPDDIIKEYGADSMRIYEMFMGPLTDSKPWNTQGLIGIFRFLNKIWLIKNKELTNETPPKEIISELHKTIKKVTEDIETLNFNTAISTLMIFINELLKHEKNYLKIFRPISIILSPFAPHLGEELWEFMGEQSSIFKNAKWPKYDLNSIIDDTREIVLQVNGKTKDKIMIKKDTDEKTLKKIAFNNQKIIQNINNKQIIKIITVKDKLVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1711_DEHMC
Sequence: MIMTNTEAVAGHKIIKNLGLVKGNTIRAKHIGKDIMASLRSIVGGEIEEYTQMLDEARNEALKRMEADAKEKGANAIICVRFSTSAVMQNASEVMAYGTAVIVE
What are the official names of this protein?
UPF0145 protein cbdbA1711.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: H20A2_CYRHA
Sequence: MKSATLLALSYLLIALYFLICEAEHSRYEEHEILEENMGDVVNLEQRSCAKPGEMCMRIKCCDGQCGCNRGTGRCFCK
What is the function of this protein?
Moderately inhibits Kv1. 1/KCNA1 and Kv1. 2/KCNA2 and weakly inhibits Kv1. 3/KCNA3, and Kv2. 1/KCNB1 voltage-gated potassium channels (PubMed:29483648).
What are the official names of this protein?
Hainantoxin-XX.2, HNTX-XX.2, Peptide F8-26.11.
What is the protein family that this protein belongs to?
Belongs to the hainantoxin family. 20 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CDV3_DROYA
Sequence: MQAMAELDDFFAKKDKKKSKNKTKFVTADEMVKNLEDGTKREVVKPKKPEAAAGGVAVVGENENSGTKVPESAPPVEEEWKEFEEEQRKDYSGLKIGQLSTITAQESAESRATRVPTAQDGGNYDEDDEDSNGYDNADVNKERVGHGPWKKVVPAEEVMQIPVPVEVEKPSSKTYVSPALRYSQQAGSGLGGGTVGGALRPRRAAPDITNTEFFPTLSAARPEEQRKKKNEPAFEEVRHGSRFQRVQESTAAPVAASNRFQSLDDEAS
What are the official names of this protein?
Protein CDV3 homolog, Protein anon-2C9.
What is the protein family that this protein belongs to?
Belongs to the CDV3 family.
Protein: GPDA_STRPD
Sequence: MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNISDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDIEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSENEWH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_DROPS
Sequence: MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNIINLGKTWEKLQLAARAIVAIENASDVFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPMTDHQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRGTISRTVEWPVVVDLYFYRDPEEAEKEEAAAKELLPPPKIEEVVDHPVEETTNWADEVAAETVGGVEDWNEDTVKTSWGSDGQF
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Required during oogenesis and imaginal development.
What are the official names of this protein?
40S ribosomal protein SA, Protein stubarista.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May associate with nascent RNP complexes within the nucleus.
Protein: RHAM_YERPS
Sequence: MIRKAFVMAVNPDAHAEYQRRHTPIWPELESVLKAHGAHHYSIFLDETRNLLFGVVEIESEERWNAVAQTAECQRWWQHMADVMPSHPDNSPVSQALREVFYLE
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_HELAH
Sequence: MRCVVYSIAKSSPLELVKIYQKQCKQFGCELELVDLFPKNIANAQKISKELAQKSYSLAFEPYLNPKAINIALHPKAERGDSFAFSKMLENYLNINFFIAGAYGFEEKFLKDCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFRHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLA_STAAE
Sequence: MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGAQTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
What are the official names of this protein?
Serine protease SplA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURA_YERPY
Sequence: MDKFRVQGRTRLSGEVTISGAKNAALPILFAALLAEEPVELQNVPKLKDIDTTIKLLSQLGTKIERNNGSVFVDASAVNEFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLNTLGAKISGAGTDRITIEGVTRLGGGVYRVLPDRIETGTFLVAAAISGGKVVCRQTRPDTLDAVLAKLREAGADIEVGDDWISLDMQGKRPKAITFRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICYGVEQLSGAQVMATDLRASASLVLAGCIAEGVTIVDRIYHIDRGYERIEDKLRALGAKIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_ESCF3
Sequence: MVSRRVQALLDQLRAQGIKDEQVLNALAAVPREKFIDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSG3_DANRE
Sequence: MNGTEGNNFYIPMSNRTGLVRSPYEYPQYYLAEPWQFKLLAVYMFFLMCFGFPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFGFTVTFYTAINGYFVLGPTGCAIEGFMATLGGQISLWSLVVLAIERYIVVCKPMGSFKFSSNHAFAGIGFTWIMALSCAAPPLVGWSRYIPEGMQCSCGPDYYTLNPDYNNESYVLYMFCCHFIFPVTTIFFTYGRLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLVAWTPYASVAAWIFFNRGAAFSAQFMAVPAFFSKSSSIFNPIIYVLLNKQFRNCMLTTLFCGKNPLGDDESSTVSTSKTEVSSVSPA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Green-sensitive opsin-3, Green cone photoreceptor pigment 3, Opsin RH2-3, Opsin-1, medium-wave-sensitive 3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CHI4_ARAHY
Sequence: MTPQGNKPSCHDVITNAWRPTATDSAAGRAPGYGVITNIINGGLDC
What is the function of this protein?
Defense against chitin-containing fungal and bacterial pathogens.
What are the official names of this protein?
Endochitinase 4, CHIT 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: YCGN_SALPC
Sequence: MADTLMSDTPFWQRKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRHYERRFEFEPDCIKLTRENLPDFEWLPMTCAYRLLAEGKPLPTWHPLLTGSKAAMHGERISVRHIAVKESEVRDWQDHILNKPSWAE
What are the official names of this protein?
UPF0260 protein YcgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: RIR2_VARV
Sequence: MEPILAKNPNRFVIFPIQYHDIWNMYKKAEASFWTVEEVDISKDINDWNKLTPDEKYFIKHVLAFFAASDGIVNENLAERFCIEVQITEARCFYGFQMAIENIHSEMYSLLIDTYVKDSNEKNYLFNAIETMPCVKKKADWAQKWIHDSASYGERLIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLLYPPSEETVRSIITDAVSIEQEFLTVALPVKLIGMNCEMMKTYIKFVADRLISELGFKKIYNVTNPFDFMENISLEGKTNFFEKRVGEYQKMGVMSQEDNHFSLDVDF
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit, Ribonucleotide reductase subunit 2, RNR2.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: PYRDA_SOLUE
Sequence: MTPQLATTICGIALKNPVLAASGTFAYGVEFEKLVDLNALGGFVVKGLSREPIEGNPPPRVFESEAGMINSVGLQNIGVRAFVAEKLPALAGLRTAVFANVFGYCTEDYVEVVRVLNDHAGLAGYELNVSCPNTAHGGIYFSNDPVLLAEVVTAAKRVATRPLIVKLSPNVSAIEPLARVAEESGADALSLVNTVISLAIDARTRRPRIGAGFGGLSGPAIKPIALRFVYQAARAVRIPVIGLGGIATGEDAAEFLIAGASAVEVGTATFWDPRAPLRIAEELGKFLEREGIRKATDLVGTLKF
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Putative dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIWL2_DANRE
Sequence: MDPKRPTFPSPPGVIRAPWQQSTEDQSQLLDQPSLGRARGLIMPIDEPLPGRGRAFSVPGEMPVRFGRGITQSIAAEPLVGMARGVRLPMEEGGFGRGRGFLLPTPEPTVGIGRGAAIGPVPTLDIQKAEVEEKMPELQAEVAPTVAKVGSPGTGSSLVSMFRGLGIEPGKTWGRGAAPVGRGAAGDMGADLQPKPTIIGASLTPEREEVRSEESISFLGRGFTGFGRAAMPHMTVGRGPIGPLSPSPSVAAPFSLISASSASEDAPVAPGTPPKVEVKIETVKEPLQKIGTKGSPIPIGSNYIPICCKNDAVFQYHVTFTPNVESLSMRFGMMKEHRPTTGEVVAFDGSILYLPKRLEEVVHLKAERKTDNQEIDIKIQLTKILPPSSDLCIPFYNVVLRRVMKILGLKLVGRNHYDPNAVVILGKHRLQVWPGYSTSIKHTDGGLYLVVDVSHKVLRNDSVLDVMNLIYQGSRESFQDECTKEFVGSIVITRYNNRTYRIDDIEWSKSPKDTFTLADGSVTTFVDYYRKNYGITIKELDQPLLIHRPKERSRPGGKVITGEILLLPELSFMTGIPEKMRKDFRAMKDLTMHINVGAQQHTQSLKQLLHNINSNNEALSELGRWGLSISQEILVTQGRTLPSETICLHSASFVTSPAVDWSRELVRDPSISTVPLNCWAVFYPRRATDQAEELVTTFSRVAGPMGMRVERPIRVELRDDRTETFVKSIHSQLTSEPRVQLVVCIMTGNRDDLYSAIKKLCCIQSPVPSQAINVRTISQPQKLRSVAQKILLQINCKLGGELWTVNVPLKYLMVIGVDVHHDTSKKSRSVMGFVASLNSMLTKWYSRVTFQMPNEEIINGFRVCLLAALQKYYEVNHAFPEKIVIYRDGVSDGQLKTVEHYEIPQILKCFETIPNYEPKLAFIVVQKRISTTLYSYGSDHFGTPSPGTVLDHTVTNRDWVDFYLMAHSIRQGCGLPTHYITVYNTANLTPDHLQRLTFKMCHLYWNWPGTIRVPAPCKYAHKLAFLSGQYLHSEPAIQLSEKLFFL
What is the function of this protein?
Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity (PubMed:18833190).  Plays an essential role in germ cell differentiation and meiosis, independently of the function in transposable elements repression (PubMed:18833190).  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (PubMed:18833190).  During piRNA biosynthesis, plays a key role in the piRNA amplification loop, also named ping-pong amplification cycle, by acting as a 'slicer-competent' piRNA endoribonuclease that cleaves primary piRNAs, which are then loaded onto 'slicer-incompetent' piwil4 (By similarity).  Piwil2 slicing produces a pre-miRNA intermediate, which is then processed in mature piRNAs, and as well as a 16 nucleotide by-product that is degraded (By similarity).  Required for piwil4/miwi2 nuclear localization and association with secondary piRNAs antisense (By similarity).  Represses circadian rhythms by promoting the stability and activity of core clock components BMAL1 and CLOCK (By similarity).
What are the official names of this protein?
Piwi-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Piwi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Probable component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis (By similarity). In mitotic and early meiotic cells of ovary, it is predominantly cytoplasmic. In primary oocytes, it is found in a granular distribution around the nucleus. Later, in maturing oocytes, it localizes to the nucleus. In testis, it is present in the cytoplasm of mitotic and meiotic germ cells, where a distinct granular distribution around the nucleus is observed.