PharMolix/UniProtQA huggingface dataset:
Protein: BBS7_MOUSE
Sequence: MDLTLSRADYLQVGVTSQKTMKLLPTSRQRATQKVVVGDQDGVVICFGVKKGEAVPVFKTLPGQKISRLELGGAVNTPQEKIFIAAGSEIRGFTKRGKQFLSFETNLTESIKAMYISGSDLFLSASYIYNHYCDCKDQNYYLSGDKINDVICLPVEKLSRVTPVLACQDRVLRVLQGSDVMYEIEVPGPPTVLALHNGDGGDSGEGLLFGTSDGRLGLIQITTSKPIHKWEIRNDKKRGGILCVDSFDIMGDGVKDLLVGRDDGMVEVYSFENANEPVLRFDQMLSESVTSIQGGCVGKDGYDEIVLATYSGWVTGLTTEPTHKESGPGEELKLNQEMQNKISSLRSEIEHLQFKVLQERENYQQSSQSSQAKSTVPSFSINDKFTLNKEDASYSLVLEVRTAIDNVLIQSDVPIDLLDVDKNSAVVSFSSCDTESNDNFLLATYRCQANTTRLELKIRSIEGQYGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGECATFYFQNTFLDTQLECVYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQVHEGNTDFLTPEYRCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPMLLEILDSYDQNTLISFFDAA
What is the function of this protein?
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia.  The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.  This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome.  Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane.  Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.  The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation.  Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity).
What are the official names of this protein?
Bardet-Biedl syndrome 7 protein homolog, BBS2-like protein 1.
What are the subcellular locations of this protein?
Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body.
Protein: C520A_DICDI
Sequence: MEILTFIIYLITFFILFDFYKKNKRYSKSPNKEANGPWSLPIIGGLHLIGDRPNRSFSELSKIYGGIYKIWLAERMLMIVTDPEIIQDIWIKQHDKFVNRPHNITSQIFSLNHKSLVFGDVDEWNKVRPKMTCHFTKIKLNSTKPKQIVNDQLKKMLKIMTTHSLDSKPFNQYVYLNTYSMNIILGLMLSIELPHSNSNDKDGQFSKVLHSIDEIFKSIGTNGPEDIFPTLLPFFKNRISTFTNHLNVIKDFIRSIYKQQIKTFDINIEPRNIMDCLISEYYEDDDQEDEVAKQELIIQLCIDMLVAATDTSASTLEWFMLFMINNPNLQEDLYEEVVNVVGKDCPYVTFDDVPKLALIKACYFEILRIRPVTSLSLPRVSMEDTTTLNDIFIPKDTIIIQNIFGMGNSEKFVSNPTVFNPSRWLEYKKMKDLNQFGNRDDSIDTTNTTTNTTLNGTTSKYYNDLERVSIPFGVGKRRCMAPSMADHNVLIAMANIVLNFTMKSSDPKQMPLSEEEQYAITIKPKYPFKVLFEKRS
What are the official names of this protein?
Probable cytochrome P450 520A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ASSY_STAAB
Sequence: MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDTGAIECHIIDATKEFSDEYVSYAIKGNLMYENAYPLFSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFVKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLNGGYSNEQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED27_HUMAN
Sequence: MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHLSRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTEDGKLDIWSKSNYQVFQKVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFRTLEAFHDTCRQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 27, Cofactor required for Sp1 transcriptional activation subunit 8, CRSP complex subunit 8, Mediator complex subunit 27, P37 TRAP/SMCC/PC2 subunit, Transcriptional coactivator CRSP34.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 27 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DSBI_CAMJE
Sequence: MSCIKMKDKCRNFSLSKWQDTRKPWLILIIVTIGLTCIAHFLFQEYLFMKPCEQCVYIRFDMLVMAIGGMIALINPANNIIKIFSYSLAFYGIWLGLEHCLTLNHIHEVVHSENPFAGVDGCREIPIYPFNLPLYKWASSWFLPTGECGMDTPVVPENAYNHLNAFQKFFIGTPPDFENGLYSNGWYLIPSLKFMNMAICCLIAFLCCFVVLFAMFIAYVLDKNKPNAKIFALVIVALVLVLKFIGESKNPNQNIASLNQVVLRYS
What is the function of this protein?
Required for disulfide bond formation in some proteins.  Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity).
What are the official names of this protein?
Putative protein-disulfide oxidoreductase DsbI.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. DsbI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXS_SHEHH
Sequence: MSFDISQFPVLAQANTPDELRQLPQAVLPQLADELRGFLLKSVGKSSGHFASGLGTVELTVALHYVYNTPFDRLVWDVGHQAYPHKILTGRREKMHTIRQKGGVHPFPWREESEYDTFSVGHSGTSISAALAMAVAAEKEQAGRKVVAVIGDGAMTGGMVFEAMNHAGDLHNDMLVVLNDNEMSISENVGALNNHLAQLMSGRFYTTIRESSKKVLQGMPVIKEMAKRTEEHLKGMVVPGTLFEELGFNYIGPIDGHDVDALVETMRNMRNLSGPQILHIMTKKGRGYEPAEKDPIGWHAVPKFDPSTFEKPAAKPCDPTFSEVFGKWLCDIAEKDEKVLGITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTFGAGFACEGYKPVVAIYSTFLQRGYDQLIHDVALQRLPVLFAIDRGGIVGADGPTHQGAFDLSFMRIVPNMVIMAPSDENECRQMLYTGYCYNDGPTAVRYPRGSATGAKQVETMTAMPIGKGLLKRQGQKIAILNFGTTLASCLVAAEALDATVADMRFVKPLDVELVKELAANHDVLVTVEENAIMGGAGSGVLELLQTLKMPKPVLLIGLPDEFIKHGAPEEITSELGLDAAGIQKQIEDFIA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: UGPA_AGRFC
Sequence: MQSVVFPNKILPYLLVAPQIILTVIFFFWPASQALYQSTMREDAFGLSSNFVGLANFSAVLSDESYLNSLKVTVIFSVLTALVSMGLALLLATAADRVVRGKGFYRTMMIMPYAVAPAVAGMLWLFMFNPAMGTLSYILRRNGIMWDPLLDGNQAMLLVVAAAAWKQISYNFLFFVAGLQAIPKSLLEAASIDGARGSRRFWTIVFPLLAPTTFFLLVVNTVYAFFDTFGIIHAVTGGGPAKATETLVYKVYNDGFVNLNLGSSAAQSVILMVIVIALTAFQFRFVEKRVHYG
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpA.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLND_NOVAD
Sequence: MLPRIANQRAIVDRRALADAVSAAFAEQGDRSRPAVVELLRGALDSGRAELARRLEARPSAGTECAHGQAFLVDQLVRVIHDHVVGKVYRASNRSTGERIAIIAVGGYGRGEMAPHSDVDIAFVTPIKPTSWCEQVIEAILYFLWDLGLKVGHSSRSLDEVVRMAKSDLTIRTALLEGRYVWGDRDLFDAASARFWNEVVNGTEKQFVAEKLQERNERHKRLGDSRYVVEPNVKEGKGGLRDLHTLYWIGKYIHKVRDASELVDVGLLTAEEYRAFRRAENFFWAVRCHLHAITRRAEDRLTFDLQREVAMRMNFADRPGKSAVERFMQYFFLQAKQVGSLTGVFLAQLDGQFARQKRSFFASLRSRRKKVGPFFIEGGKLGVPAEDTFQQDPVRLVELFAVAASEKVEIHPEAMRLARRDAGLIDAAVRKDQRANALFLDVLTSRNDPETVLRWMNEAGVFGRFVPDFGRVVAQMQFDMYHHYTVDEHTIRAIGLLASIEKGEAKADHPLASEVVGKVASRRVLYVATLLHDIAKGRRGDHSVLGAEVAMKLCPRLGLSAAETELVAWLVRWHLLMSATAFKRDLADYKTIADFVNTVQSQERLRLLLLLTIVDIRAVGPGVWNSWKRQLLGDLFVSAEEVLRLGHKQHGRAERIIAKKKAVGAILKERDNLIGTVGRQLGDAYWIAEPEDIIALNLQQMDQALGELLSVEAHWYPARGATLVTVLAADHPGLFYRIAGGIHLAGGNIIDARIHTARNGTAVDNFLVQDPLGRPLNEASQIERLKNAIADALANRVKLVPQLAARPLARPRADAFDVRPIVIFDNKASNRFTVIEVGARDRPALLNRLARALFEARLIVHSAHIATYGERAVDTFYVTDVLGEKVDSEARMKAVEKRLLEAAEDRKVKDAA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: AROA_BIFLD
Sequence: MTERLTNLWPAPLAAQPLNATVTVPGSKSLSNRYLILAALGSKPVTLIGLLRSRDTDLMMGALEALGVRCDVDSATDTTVTVTPPVSGRFHGNVNVFCGLAGTVMRFVPGLALFADGPVNFDGDEQAYARPMKPVLDGLEQLGATVDYHGEVGRLPFTITPPATLPAAQAQVSIDSSGSSQFISGLLLISSKLPGGLHLAHTGEKTPSLPHIRMTVADVTGAGGAVEADESARTWTVEPRAMQLSSKVTVEPDLSNAAPFLGAALIAGGTVRVPHWPETTTQPGGLLPGYLEQMGAEVSFPTIGGVRYCEVTGDGTVRGLGTFDLTAAGEIAPSLAAILVFADKSTDMVGIGHLRGHETNRLEALVNEIRRVGGAAEELPDGLRIEPVPAETLHGAVMETYADHRMATFAAMLGLRIPDIEVINVATTRKTLPDFVGMWSGMLRQ
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_MYCTO
Sequence: MARLVGVDLPRDKRMEVALTYIFGIGRTRSNEILAATGIDRDLRTRDLTEEQLIHLRDYIEANLKVEGDLRREVQADIRRKIEIGCYQGLRHRRGMPVRGQRTKTNARTRKGPKRTIAGKKKAR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: O16D_CONAB
Sequence: VLIIAVLFLTACQLTTAETSSRGEQEHLALRSTDKNSRMTKRCTPRHGVCFYSYFCCSKACNPSSKRCL
What are the official names of this protein?
Conotoxin AbVID.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMM_SALCH
Sequence: MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIYECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELMKFCRKFTVPLRAALRDVGVLTNYETPKRPVVHVFFIAPGCCYTGYSFAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVCDMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNAQIQARQLYHDREEVTVHVRRLWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_DICNV
Sequence: MGKKLVVIGAQWGDEGKGKIVDLLTERAGAVVRFQGGHNAGHTLVVHGKKTVLHLIPSGIMHDHVMSYIGNGVVLCLRALFEEIKALTAEGIPVKERLRISPACALILPSHIALDQARETARGKDKIGTTGRGIGPCYEDKIARRGLRLEDLRHPDDFRQKMQALMTYHNFLLENYYHQTAVDIDATIEEWLAYGKDVLPLMEDVTLALQRHQEQNVIFEGAQGAMLDIDQGTYPFVTSSNTAAGSASCGSGVGPHQLDYILAITKAYTTRVGSGPFPSEQINDIGEHLAKVGVEVGASTGRRRRCGWLDLPALRRALLNSSFDGVCLTKLDVLDELDEIKICTAYCHHEQIIDVAPLGSESLAECEPVYETFTGWKTSTFGIKNEAELPQKARDYIAKIEEYLGIPVVIISTGADRSHTIMRQSLLE
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR4_HAEI8
Sequence: MTVKTFRGSPALSEFRLTQLQQKCQQYQLPITSVYAEYLHFVEQKTSLVEDEIVKLQALLHYGSMFSELKPAGYCLIVTPRVGTISSWSSKATDIAHNCGLSKVNRIERGIAYYFNIERDLTEAELATLKDLLHDRMLETVLNHETEAALLFTQQEPKALTTIDILNGGRQALERANIALGLALADDEMDYLVESFTALKRNPQDVELYMFAQANSEHCRHKIFNADWIIDGKKQDKSLFKMIKNTFEQTPDFVLSAYKDNAAVMEGSKVGRWFPDPDGQYRVHQEDAHILMKVETHNHPTAISPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFSVSNLVIPNFEQPWENPLSKPNRIASALDIMIDAPLGSAAFNNEFGRPALLGYFRTYEEKVNSFAGKEVRGYHKPIMLAGGIGNIRGEQVQKGEIPIGAKLIVLGGAAMNIGLGGGAASSMDSGKSKEDLDFASVQRENPEMERRCQEVIDRCWQLGEENPILFIHDVGAGGLSNAMPELVHDGRRGGKFDLRSILCDEKGMSPLEIWCNESQERYVLAVAPENLELFTALCERERAPFAVIGEATQAEHLILHDSHFDNNPIDLPMNVLLGKTPKMTREVLSKTVENQSLKTEGIQLKEAFHRVLRLPVVAEKTFLITIGDRSVTGMVARDQMVGPWQIPVSDVAVTTASLDSYHGEAMAMGERSPVALLNFSASARLAVAEAITNIAGTHIGEMKRIKLSANWMSAAGHTGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTTWIDNGEQKSVTAPLSLVISAFARVEDVRKTLTPQLRTDKGLSSLLLIDLGEGHNRLGATALAQVYKQLGDKPADVVKVQRLKDFYNAMQTLVAEDKLLAYHDRSDGGLITTLAEMAFAGHCGVEVDISALGDNDLAVLFNEELGAVIQVADSQLESVREVLKAHNLLGITHQLGTVTADDRFEISRGSHKLFSEKRSELRSIWAELTYQMQRLRDNPECAEQEFEAKKNPDDKGLSAFLTYDVNEDITAPFINKGVKPTIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSDLMIGRRNLAEFNAMVACGGFSYGDVLGAGGGWAKSILFNPKLHEQFSQFFINPNTLTLGVCNGCQMISNLAEIIPGTENWPHFVRNKSERFEARVSLVKINEVDSVWFAGMAGSHMPIAVSHGEGQVKFKSVEQFAGLKAQGIIAAQYIDNNGSPTELYPANPNGSAEGITAITNLDGRVAIMMPHPERVFRAVSNSWHPENWTEDGAWMRLFRNARMVF
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLAS_GLOC7
Sequence: MLKKLGVLLSAIVLVIASFFVTVTPALAETYTVKMGSDQGLLKFDPPQLTIKAGDTVKWVNNKLAPHNAVFDNSKVPDSVSATKISHKALVFSPGESFTTTFDEPGTYTYYCEPHRGAGMVGTITVE
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the thylakoid inner membrane surface.
Protein: SECA2_MYCBP
Sequence: MNVHGCPRIAACRCTDTHPRGRPAFAYRWFVPKTTRAQPGRLSSRFWRLLGASTEKNRSRSLADVTASAEYDKEAADLSDEKLRKAAGLLNLDDLAESADIPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLDAMGLTVGWITADSTPDERRTAYDRDVTYASVNEIGFDVLRDQLVTDVNDLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRETPRLEIIRLVAELVGDKDADEYFATDSDNRNVHLTEHGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYQLGVSPIPPNKPNIREDEADRVYITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEAGKYGAVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVVAANLDHNKLPMATDENGRIVSPRTGSLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVERRNTLLRTVTAREELAELAPKRYEELSDKVSEERLETICRQIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEAAQQTFETANVLDHEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSALSLPGVFR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: OMT1A_MENPI
Sequence: MAPEEDSLALAEAWNHGFGFIKTSIVKTAVELEIPDILESRGAPVSIPELATAVDCSADRIYRVMRFLAYHGIFKRTKPPPESTEGGSVYYAQTPVSRRLTRENLGPFVLLQGTMREPSGCVTAETLRTSKRPGVVNENESDHLYEDPVFSMKVFRDAMASHARMTTAAVIENYGEGFQGVGSLVDVGGSYGMALSMLVKAFPWLRGICFDLPEVVARASPLKGVEFVGGTMFESIPKADVVMLMFVLHNWSDEECVEILKRCKDAVSKDKGKVIIIDAVIDEDGDGDEFTGARLGLDVTMMATMFEGRERTYVEWARIINEAGFRRHVVKNIKTLESVIEAYP
What is the function of this protein?
Flavonoid 7-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as pebrellin, aroma compounds which contribute to the flavor of peppermint, and exhibit pharmacological activities such as anti-allergic, anti-oxidant, antibacterial, anti-proliferative, and anti-inflammatory effects (PubMed:14697269).  Catalyzes S-adenosylmethionine-dependent regioselective 7-O-methylation of flavonoids; active on various hydroxylated flavonoid substrates, including luteolin (LUT), quercetin, kaempferol, isorhamnetin, apigenin (API), scutellarein (6-hydroxy-apigenin, 6-OH-API, SCU), 7,8,4'-trihydroxy-flavone and naringenin (NAR), and, with a lower efficiency, 7,8,3',4'-tetrahydroxy-flavone, taxifolin, hesperetin and genistein (PubMed:14697269).
What are the official names of this protein?
Flavonoid 7-O-methyltransferase 1A, MpOMT1A, 7,8,4'-trihydroxy-flavone 7-O-methyltransferase, Apigenin 7-O-methyltransferase, Isorhamnetin 7-O-methyltransferase, Kaempferol 7-O-methyltransferase, Luteolin 7-O-methyltransferase, Naringenin 7-O-methyltransferase, Quercetin 7-O-methyltransferase, Scutellarein 7-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: PAX_I51A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKKQLKKDLKSQEQCAGSLTKVSRRTSPALRILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: ABCC2_DICDI
Sequence: MIKNLKQKIKNRFSYSLLSEDDNTDYFSKPCPEDNATLWQRFTFGWTERMLMTGYFNGPLEMKDVSDLPDRNKVNITAPFLDTIDYNSKYPLIKQIYKEFVSRNKISVATKIFVAIVSILSPLCLKYFIYYIKLDESQKTFKFGFLLCVLLFLSSLSLTLSQQYGYWFGLQTSLHARGAITQKIFEKTLRLSNQAKRLYNSGTIMNIISVDVGTFSDFFWNNHIEIFVFPFQILALLILLCWIVGLSGLVGFGVMVVSIPLCTFLSTKIAKNLRISLGYADTRCNLTSEFINGIRFLKLYAWEQLFLDRIEEQRTLQLKYLYRRAIYWILDRMITQVTSALVLVATFSTYALTGNQMTLEVAFTAMTIFVNLRRPLEMLPEAIHRALSLIPSSKRIENFLQSPEIQDQPFLEQYSNNKLSIRNNNNNNNNVSSTSSIASSASSNELFDVKINNGTFDWNEIDDLDSGMIINDVRGFAISSDINDMDEMILGDEKVGKSNDTNNGIEYDGAVQPSSSSYVLNNINFIAPAGKLTVICGIVGSGKTSLVSGLIGEIYRVSGSVNIPNNISFTTQQPFLLSTSLRDNILFGKPMNMERYKKVIDACCLTPDLLQLAAKDLTEIGERGINLSGGQKQRISLARALYSDSDCFILDEPLSAVDPEVASHLFDHCIQGMMKDKTRILVTHQLQFIPSADHIIVVDNGVLTQGTYSELKEKGIDFESIMKTKKLNIDENDQSSTSTTDKKSSTSSSSSELKKSTSLLNSTKELDINTIISEKNDPNLIEKAKLLVKEDRNEGEVGFEVYRQYFRHGSLNLFFLTCALYFISQIIFQLSDFWLTIWTNDETNQHDDKYYILYYCIFIGAFIVFLVVRYFMMASITFAASKKLHSELLNSVAFASCQFFDTNPSGRILNRFSKDISDIDLILMENFSDVLQCGSTVVVALFMMIYITPLISIPFAILVVVYYVIQKLYRASSVELKRMESITRSPVFSLLAEAYNGLVTIRCYQQQKRFIEMMQNHININLRLFFYSFSVHRWVGIRLEFITALIVFFTAFSSLFSSNTGFSVLAVTTALGICSYLNWTIRQMTELEVKMNSVERVESYIKTPREGIRHTSEFEDEIDIDGEIEMDFTKWPSRGEVEFKNVEIKYRPTADPSLKNISFKINAKDHIGVVGRTGAGKSTVGISLFRMVECSKGSIFIDGVDISKVGLHELRDALGIVPQDPFIFSGSIRMNIDPFNKYTDDEIWTALEKVKLKDAISSMPLKLESGVQENGDGLSFGQKQLLCLSRTILKNSKVVLMDEATSGIDYVTAALLKQTIDENFNDCTMLTIAHRLDTIIDSTKIAVIDKGELVEYDTPMNLIKTEGSRFKKLVKYQTDFYEESQKKF
What are the official names of this protein?
ABC transporter C family member 2, ABC transporter ABCC.2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CLPX_DEIGD
Sequence: MTGRSGNIGGDRCSFCGRQHPQIAQLIEAPGRAAFICNECTDRAFELVRQNKAKGSEFRLEELPSPKEIKAYLDEFVIGQDEAKKALAVAVVSHYQRLAHPDVNLQKSNILLIGPTGTGKTLLAQSLAEMLEVPFAIADATTLTEAGYVGDDVENVIVRLLQAAEYDVAAAERGIIYIDEIDKIARKSEGTSITRDVSGEGVQQALLKIIEGTVAQVPPQGGRKHPQQELVQVNTKNILFIVGGAFENMAEIARARTNVRSVGFGAEHKGEEKEELRFLPEDLVKFGLIPEFVGRLPLVVQLQDLDEDALVRILTEPQGAIVKQYQALFGFQGVDLTFTEEALREVAHRAKARKTGARGLRAVLEKAMTDLLFELPIEGLKELRFDAENIDHPLALIESGGLKKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YORW_TTV1K
Sequence: MIAEQIFIIILVLTVLHTAIERIAKRSLSYSNVNYTYTQSISFLVGYTIVYIIMSHISHAVIISIMIMISYAIYIVIKMRNNQQIQNDIEMFMFGMIAGLGIEIVG
What are the official names of this protein?
Uncharacterized 12.1 kDa protein.
Protein: GLYA_ACIET
Sequence: MYQRNILVEQTDPEVWAAIQAEDRRQEEHIELIASENYASPAVMAAQGSQLTNKYAEGYPGKRYYGGCENVDVIEQLAIDRIKQLFGAEAANVQPNSGSQANQAVLMAFLKPGDTILGMSLAEGGHLTHGMPLNMSGKWFNVVSYGLNDKEEIDYDALEAKAREHKPKLIIAGASAYALRIDFERFAKIAKEVGAIFWVDIAHYAGLVVAGEYPNPVPFADVVTSTTHKSLRGPRGGIILMKAEHEKAINSAIFPGLQGGPLEHVIAAKAVAFKEALSPEFKQYQQQVTKNAKVFAETLIQRGLRIVSGRTESHVMLVDLRAKGITGKEAEAALGKAHITINKNAIPNDPEKPMVTSGIRVGTPAITTRGFKEEETRLTANLVADVLDNPHDEANLEAVRAKVHALTSRFPVYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.