PharMolix/UniProtQA huggingface dataset:
Protein: ARG56_DICDI
Sequence: MLRNSNKLIKSVIKNESTLLKCKNNNQRVVNYSSSSTSITSGNGIYSQIKKIEEFVSKKPSVTKVSSSSATINFNTSKSGSTNTTAVDYSKSVKIKDQKQIVLVKIGGGVIESDISSLIGSLNFLKKIGLFPIVVHGGGPQLNAELAAAGEPAEYVEGLRVTPPSVLAIAQRVFLRENLKIVEALESSGTKARPVTQGVYQATPLDPKLYGFVGNVTKIHTDALASCITNDYVPVISSLAMTPEGQVLNINADVAALELAKSINPLKILFINTTAGMKDGDGKVMQHIKLDEQYADLMKQPWVKHGTKLKLKEFKSCLDVLPPSTSITITSPDLLMKELFAKDGSGTTVERGEVMHSHESPSFDETKFFALIEKSTGTKGGRIDYQQLKTDLSKGVVKAFVNSHYTAGILVRPLSSGSSVSYVDQFFFFNNSIQSTEDSESVFKKMFENSSYIWKESSNNQLNNEWFKKIATGFITGATNNIFWTNIDTNKIENSIKECLSQSSTYLSGITKAASSKSASEKLLQDKNHKFRVGLIGARGFTGGNLVRLIDGHPNLELAIASSSTNFGKPITTEFPQLKSNLKFDNVKPENIDIFTRDHGIDGWFMALPDKISSPYIQTLENSSESPVLVDLSSDHRFNEKWTYGQPETNRAAIKESKLIANPGCYATGMFLTLKPFVNDLVTPPSCFGISGYSGAGSKPSEKNDPTRLSDNILPYKLVQHTHELEVSHQLGSPIYFMPHVGQFFQGITLTISMELKYPMTKEQVVERYQKFYQNEPLIKIDKDGIPEVKSNSGKHTVTIGGFAVNGNHLVVVTTLDNLLKGAATQALQNMNICLGLDELASIKNEL
What are the official names of this protein?
Bifunctional protein argC, mitochondrial.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAGSA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSBF_CALFG
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KV2A6_MOUSE
Sequence: DIVMTQTAPSALVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQCPQLLIYRMSNLASGVPDRFSGSGSGTAFTLRISRVEAEDVGVYYCMQQREYPYTFGGGTKLEIKR
What are the official names of this protein?
Ig kappa chain V-II region 7S34.1.
Protein: NMT_PLAFA
Sequence: MNDDKKDFVGRDLYQLIRNAKDKIKIDYKFWYTQPVPKINDEFDENVNEPFISDNKVEDVRKEEYKLPSGYAWCVCDITKENDRSDIYNLLTDNYVEDDDNVFRFNYSSEFLLWALSSPNYVKNWHIGVKYESTNKLVGFISAIPIDMCVNKNIIKMAEVNFLCVHKSLRSKRLAPVLIKEITRRINLESIWQAIYTAGVYLPKPISTARYFHRSINVKKLIEIGFSCLNTRLTMSRAIKLYRIDDTLNIKNLRLMKKKDIDGLQKLLNEHLKQYNLHAIFSKEDVAHWFTPIDQVIYTYVNEENGEIKDLISFYSLPSKVLGNNKYNILNAAFSFYNITTTTTFKNLIQDAICLAKRNNFDVFNALEVMDNYSVFQDLKFGEGDGSLKYYLYNWKCASCHPSKIGIVLL
What is the function of this protein?
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (PubMed:10816442, PubMed:18973776).  Myristoylates adenylate kinase AK2 (PubMed:18973776).  During the asexual blood stage, may myristoylate proteins such as ARO, CDPK1 and GAP45 (By similarity).  Probably by mediating protein myristoylation, plays a role in the assembly of the inner membrane complex during the early stages of schizogony and in the formation of rhoptries in the late stages and thus merozoite egress (By similarity).
What are the official names of this protein?
Glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, N-myristoyltransferase, PfNMT.
What is the protein family that this protein belongs to?
Belongs to the NMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_NITOC
Sequence: MYLTLLKSKLHRACVTHIELEYEGSCAIDSVLLSTAGIQEYEQIHIYNLTNGERFVTYAIRAEDNSGIISVNGAAAHKACPGDRLIICTYAVFERSEMDSFKPLLIYLDDRNFITHTGNAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_YERPE
Sequence: MNQFYKRHFLRLLDFTPAEIIALLDLATELKKDKKSGCEQQKLVGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPGGSQIGHKESIKDTARVLGRMYDGIQYRGYGQRVVETLAEFAGVPVWNGLTDEFHPTQLLADLLTMREHLPNKSLNKMTLAYLGDTRNNMGNSLLEAAALVGMDLRLVAPKACWPEEAFVISCQALAQKTGGKITLTEDIAEGVNGADFLYTDVWVSMGEPKEVWQERINLLKPYQVNMRVLTLTGNPQVKFLHCLPAFHDDQTTIGKQMAEQYDLPGGMEVTEEVFESAHSIVFDQAENRLHTIKAVMVATMSKI
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODPB_CHLAT
Sequence: MAVRFLFEALQKAIDEEMEREKRVVLIGEDIGHYGGSYKVTQGLYGKYGKHRVIDTPIAEYSFVGAAVGAAATGLIPVVEGMNMAFILLAYSQISNNMGMLCATSGGHFQVPMVLRGPGGIGKQLGAEHSQRLESYFQSVPGLQIVTCSTPYNAKGLLKSAIRSKNPILFIEHVLLYNLKGEVPDNDYLLPLEKAELVREGSDITVLTYSRQRYNVIQAVKVLVEEGYDPEVIDLISLKPFDMETIGKSIQKTHKVLIVEECMMTGGISNVLQSLIIDNFFDALDAAPLILSSPNVPTPYTGPLEEATVVQTIDIIESIEYGITGKPPKPRTAKK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CCD43_HUMAN
Sequence: MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR
What are the official names of this protein?
Coiled-coil domain-containing protein 43.
What is the protein family that this protein belongs to?
Belongs to the CCDC43 family.
Protein: RGMA_CHICK
Sequence: MGRGAGSTALGLFQILPVFLCIFPPVTSPCKILKCNSEFWAATSGSHHLGAEETPEFCTALRAYAHCTRRTARTCRGDLAYHSAVHGIDDLMVQHNCSKDGPTSQPRLRTLPPGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDTFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSSATATSKLTIIFKSFQECVEQKVYQAEMDELPAAFADGSKNGGDKHGANSLKITEKVSGQHIEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQTFRLAQAAEGRARRKGPSLPAPPEAFTYESATAKCREKLPVEDLYFQSCVFDLLTTGDVNFMLAAYYAFEDVKMLHSNKDKLHLYERTRALAPGNAAPSEHPWALPALWVALLSLSQCWLGLL
What is the function of this protein?
Acts as an axon-specific repulsive guidance molecule in the retinotectal system.  Repulsive for a subset of axons of the temporal half of the retina.  Provides thus positional information for the temporal axons invading the optic tectum in the stratum opticum.
What are the official names of this protein?
Repulsive guidance molecule A.
What is the protein family that this protein belongs to?
Belongs to the repulsive guidance molecule (RGM) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: MON1B_HUMAN
Sequence: MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSPSPPPQSEALSSTSRLWSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTSQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAFHAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFTGL
What are the official names of this protein?
Vacuolar fusion protein MON1 homolog B, HSV-1 stimulation-related gene 1 protein, HSV-I stimulating-related protein.
What is the protein family that this protein belongs to?
Belongs to the MON1/SAND family.
Protein: H2B7_ORYSJ
Sequence: MAPKAEKKPAAKKPAEEEPAAEKAEKAPAGKKPKAEKRLPAGKGEKGSGEGKKAGRKKGKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAGESAKLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.7.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RUVA_ACTP2
Sequence: MIGRLHGKIIEKQPPEMVIDVQGVGYEVLLPMTSFYSLPQVGEEATIFTHLVVREDAHLLFGFAQKQDRTLFRELIKTNGVGPKLALAILSAMSVSQFANAVENEELAKLTKIPGIGRKTAERLLVELKGKFKGVAQSDFFEEHSVETIVATHSHDPADEARDALVALGYKLADAEKMIKKVNKAGATSEQLIREALKASL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RS16_PSEA7
Sequence: MVTIRLARGGSKKRPFYHLTVTNSRNARDGRFVERIGFFNPVATGGEVRLSVDQERATYWLGQGAQPSERVAQLLKDAAKANA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ATD2_SCHPO
Sequence: MKEEASEHGGSADETQELSPVSDSSDEMPNNAKRRRRSQSMIANKRIHQAFQEDEGDEDWEEEEHKPKAKRRYNTRSNESFSEGDDEPFEVSESSALEDELSDSEDSFIRSVRSKPKYKPGTRRSTRLRNRRSQDEEESEEEHRPILRERTSRINYSVPLAFPPVDEMDGDPSSQVNQSRSRKTHSELAITKLLRQQVSSFMPYIDSSGSESESDNTRIKKSSAKTIKALTDPANSGGPPDFGRIREKSDLADSDPLGVDSSLSFESVGGLDNYINQLKEMVMLPLLYPEIFQRFNMQPPRGVLFHGPPGTGKTLMARALAAACSSENKKVSFYMRKGADCLSKWVGEAERQLRLLFEEAKSTQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGMESRGQVIIIGATNRPDAVDPALRRPGRFDREFYFPLPDRDARKKIIEIHTRNWDPPVPEWLCSMLAEKSKGYGGADLRALCTEAALNSIKRTYPQLYRSTKRLQIDPKTIKVKVKDFVMSMKRMIPSSERSSISPSKPLSPELKPLLNEAFQDIEKTLQKLMPVASKLNPLEEVMYDDPKENDFEYQQRLETFETLRIYKPRFLICGRKGLGQTALGPAILQQYEGVHVQSFDMSTLLQDSTQSIETSIIHLFLEVRRHTPSIIYIPDIDNWLNVLPLTAITTFSSMLERLDFSDQILFLALSSSPLSELHPQLREWFSSKQSVYSLQYPTRDSIIAFFQPILELIKASPTELPGGIPRKRRVLPELPLAPDPPPFTSQKITLKQTKQADMRLLNKLKIKLNALLGSLRARYRKFKKPLIDFNDIYCVDPETGHSYRSREECHYEFVDDVVKQIGSDQKFSMMSLEEIEKRTWDNCYCTPKQFVHDIKLILRDALQLEDSETIKRAQEMYANVLLGVEDMEDDQFSQRCERMALREAERRKLRHGKLQKHLDETKADMQFTSEKPSVDESITEVDDAIKDGPPVLAETLTNSLMEDVGPENVDMDIEDNEIFTNQSTMSVPSMLVENEESPKPDEYIDQKDKVQSPLLNGKSPVGVPSEAALRVSTDVSTNISSNGRADIPVDTLITSPADVPNNAPTDAHNITSADGHIENIEQEVVFPDLVFDEDRLTPLKQLLIDSTTGFTVDQLLHLHSFLYQIIWNTKSEWNRNSVVDECERAVKEFMINALQ
What is the function of this protein?
ATPase histone chaperone which facilitates loading of histone H3-H4 onto DNA in an ATP-dependent manner (PubMed:31848341, PubMed:33658433).  Plays a genome-wide role in nucleosome organization and establishment of chromatin (PubMed:26582768, PubMed:31848341).  Also plays a role in heterochromatin assembly by stabilizing recruitment of the histone methyltransferase clr4 to methylated histone H3, to promote the transition from H3K9me2 to H3K9me3 (PubMed:32269268).
What are the official names of this protein?
ATPase histone chaperone abo1, ATPase family AAA domain-containing protein abo1, AAA-ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL34_HELPS
Sequence: MKRTYQPHNTPRKRTHGFLVRMKTKNGRKVINARRAKGRKKLSV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RUVB1_GIBZE
Sequence: MVQISEVKGNKRDNRTAAHTHIKGLGLKSDGYAEKQAAGFVGQAAARESCGVVVDLIRAQKMAGRGVLLAGGPGTGKTALALAISQELGTKIPFCPIVGSEIYSAEVKKTEMLMENFRRAIGLKVRETKEVYEGEVTELTPEEAENPLGGYGKTISTLLIGLKSAKGQKKLRLDPSIYEAIQKERVTVGDVIYIEANTGACKRVGRSDAYATEFDLEAEEYVPIPKGEVHKKKEIVQDVSLHDLDVANSRPQGGQDIMSMMGQLMKPKMTEITDKLRGEINKVVSKYIDQGVAELVPGVLFIDEAHMLDVECFTYLNRALESPIAPIVVLASNRGMCTIRGTDDIVAAHGIPSDFLARMLIIPTTPYEADEIKRIVRIRSTTEGVSVSDAAIDKISEHGVRISLRYCLQLLTPASILAKANGRSQIDVQDVAECEDLFLDASRSAALLSSEAGRGYLA
What is the function of this protein?
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.  The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair.  Also involved in pre-rRNA processing (By similarity).
What are the official names of this protein?
RuvB-like helicase 1.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_STAA1
Sequence: MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAIYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTHGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFNQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_ACET2
Sequence: MRNVKLIIEYDGTNYHGWQKQKNAKTVQDTIERAIKGLTGEKVDLIGASRTDFGVHALGQVANFITNSGIPGDRFSYALNRMLPDDIVIKESQEVDMDFHARYKAKGKRYRYLIYNSQFPSALLRHRTYHVSHKLDFESMQRAASYFLGTHDFSAFRSSGSSAKTSVRTITDVSLEREDKIVKFEIAGDGFLYNMVRIIVGTLMEVGIGKIRADEIPQIIESRKRKRAGRTAPAEGLYLVEVYY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ALLTR_EUSSE
Sequence: GFKNVALSTARGF
What are the official names of this protein?
Allatotropin-related peptide, ATRP.
What are the subcellular locations of this protein?
Secreted.
Protein: C7162_ARATH
Sequence: MYLTIIFLFISSIIFPLLFFLGKHLSNFRYPNLPPGKIGFPLIGETLSFLSAGRQGHPEKFVTDRVRHFSSGIFKTHLFGSPFAVVTGASGNKFLFTNENKLVISWWPDSVNKIFPSSTQTSSKEEAIKTRMLLMPSMKPEALRRYVGVMDEIAQKHFETEWANQDQLIVFPLTKKFTFSIACRLFLSMDDLERVRKLEEPFTTVMTGVFSIPIDLPGTRFNRAIKASRLLSKEVSTIIRQRKEELKAGKVSVEQDILSHMLMNIGETKDEDLADKIIALLIGGHDTTSIVCTFVVNYLAEFPHIYQRVLEEQKEILNNKDVNEKLTWEDIEKMRYSWNVACEVMRIVPPLAGTFREAIDHFSFKGFYIPKGWKLYWSATATHKNPEYFPEPEKFEPSRFEGSGPKPYTYVPFGGGSRICPGREYARLEILIFMHNLVKRFKWEKVFPKENKLVADPAPIPAKGLPIRIFPQS
What is the function of this protein?
Possesses triterpene oxidizing activity.  Catalyzes the C28 hydroxylation of alpha-amyrin, beta-amyrin, and lupeol, producing uvaol, erythrodiol, and betulin, respectively.  Catalyzes the C28 carboxylation of alpha- and beta-amyrin.  Possesses 22alpha-hydroxylation activity against alpha- and beta-amaryn.
What are the official names of this protein?
Cytochrome P450 716A2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACEK_SALSV
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWEPLLMRILSDLPLRLPWQNKSRDIRYIIAHLTETLGEDALPRCHVQVANELFYRNKAAWLVGKLTTPDGTLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRVFKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMALLRQEAPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRRQRFSVRYGAISSTANSS
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_PSEPW
Sequence: MNPTWWRDACQPLDTAAMDQARARQQQLTKPAGSLGQLEALAVHLAGLQGVERPNLDQVAITIFAGDHGVVEEGISAYPQAVTGQMLRNFVGGGAAISVLARQLQASLEVVDLGTIDPHLELPGVRHLRLGSGTANFARQPAMTEVQLRSALQAGRDSVLRAAQSGAQLFIGGEMGIGNTTAAAALASTLLGCPARELSGPGTGLDTAGVRHKAEVIERALVLHGLRADDPLQALGCVGGFEIAALAGAYLACAQQGIAVLVDGFICSVAALVAVRLNPQCRAWLLFAHQGAEPGHKALLDALQAEPLLALGLRLGEGSGAALAVPLLRLACVLHGQMATFAEAAVADRPV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RLMF_ECO27
Sequence: MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIQANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSATAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_BRASB
Sequence: MHATSHEPAVWHGTTILTVRKGGRVVIGGDGQVSIGQTVIKSNARKVRKLGKGDVIGGFAGATADAFTLFERLESKLEQYPGQLTRAAVELAKDWRTDRYLRRLEAMMIVADKEVSLVLTGTGDVLEPEAGVMAIGSGGNYALAAARALIDTDKDAESIVRRSLDIAADICVYTNRNITIEALAAE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_HAEDU
Sequence: MASQFELRIVSAEKQIFNGQVVSVRVSGVEGELGIYAGHTPLLTAIKPGMVKYTLEDNKEEFIYVSGGFLEVQPTIVTVLADIAIRGEELDQQRIIAAKRKAEDTLSKTNNAELSAKLAREIAKLRVYEIVNSKLTKKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y656_MYCBO
Sequence: MALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGYDALVAPLTFVTILAKYVQLDFFRHVDVGMETMQIVQVDQRFVFHKPVLAGDKLWARMDIHSVDERFGADIVVTRNLCTNDDGELVMEAYTTLMGQQGDGSARLKWDKESGQVIRTA
What are the official names of this protein?
UPF0336 protein Mb0656.
What is the protein family that this protein belongs to?
Belongs to the UPF0336 family.
Protein: MOTI_HUMAN
Sequence: MVSRKAVAALLVVHVAAMLASQTEAFVPIFTYGELQRMQEKERNKGQKKSLSVWQRSGEEGPVDPAEPIREEENEMIKLTAPLEIGMRMNSRQLEKYPATLEGLLSEMLPQHAAK
What is the function of this protein?
Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
What are the official names of this protein?
Promotilin.
What is the protein family that this protein belongs to?
Belongs to the motilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: S1C2A_RAT
Sequence: MALAPELSRQTKLKEVAGIPLMDPTVNNWSQIQTFKAKPDDLLICTYPKSGTTWIQEIVNMIEQNGDVEKCQRTIIQHRHPVIEWARPPQPSGVDKANAMPAPRILRTHLPPQLLPPSFWTNNCKYLYVARNAKDCMVSYYHFYRMCQVLPNPGTWNEYFETFINGKVSWGSWFDHVKGWWEIRDRYQILFLFYEDMKRDPKREIQKVMQFMGKNLDEEVVDKIVLETSFEKMKDNPLTNFSTIPKTIMDQSISPFMRKGIVGDWKNHFTVAQNERFDEIYEQKMDGTSLNFCMEL
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation.  Sulfonates p-nitrophenol, a small phenolic compond.  Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol.
What are the official names of this protein?
Sulfotransferase 1C2A, ST1C2A, rSULT1C2A, Sulfotransferase K2.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm. Lysosome.
Protein: RL4_FUSNN
Sequence: MAVLNIYNLAGEQTGTVEVNDAVFGIEPNKVVLHEVLTAELAAARQGTASTKTRAMVRGGGRKPFKQKGTGRARQGTIRAPHMVGGGVTFGPHPRSYEKKVNKKVRNLALRSALSAKVAAGNVLVLDYDGIETPKTKVIVNLVNKVDAKQKQLFVVGDLIKDYNLYLSARNLENAVILQPNEIGVYWLLKQEKVILTKEALATVEEVLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y1273_MYCTO
Sequence: MLLALLRQHIRPYRRLVAMLMMLQLVSTLASLYLPTVNAEIVDDGVAKGDTATIVRLGAVMLGVTGLQVLCAIGAVYLGSRTGAGFGRDLRSAMFEHIITFSERETARFGAPTLLTRSTNDVRQILFLVQMTATVLVTAPIMCVGGIIMAIHQEAALTWLLLVSVPILAVANYWIISHMLPLFRRMQSLIDGINRVMRDQLSGVRVVRAFTREGYERDKFAQANTALSNAALSAGNWQALMLPVTTLTINASSVALIWFGGLRIDSGQMQVGSLIAFLSYFAQILMAVLMATMTLAVLPRASVCAERITEVLSTPAALGNPDNPKFPTDGVTGVVRLAGATFTYPGADCPVLQDISLTARPGTTTAIVGSTGSGKSTLVSLICRLYDVTAGAVLVDGIDVREYHTERLWSAIGLVPQRSYLFSGTVADNLRYGGGPDQVVTEQEMWEALRVAAADGFVQTDGLQTRVAQGGVNFSGGQRQRLAIARAVIRRPAIYVFDDAFSALDVHTDAKVHASLRQVSGDATIIVVTQRISNAAQADQVIVVDNGKIVGTGTHETLLADCPTYAEFAASQSLSATVGGVG
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein MT1311.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.