PharMolix/UniProtQA huggingface dataset:
Protein: MNMA_SALTO
Sequence: MVGVRVLAAMSGGVDSAVAAARAAEAGHDVTGVHLALARNPQTYRTGARGCCTLEDSRDARRAADVLSIPFYVWDMADRFQADVVDDFVAEYAAGRTPNPCLRCNEKIKFAAVLDRAVALGFDAVVTGHHARLGADGLLRRSVDLAKDQSYVLGVLTREQLSRSMFPLGDSTKTQVRAEATRRGLAVADKPDSHDICFVADGDTRGFLARRLGTTPGDVVDGDTGEVVGRHTGAYAYTVGQRRGLHLDRPAPDGRPRYVLSITPKTNTVTVGPAEALAVSQVQARRPVWIGGPRPADPVECEVQLRAHGDVVPATVAVTDDGLRAELHQPLRGVAAGQAIVAYRPDPAGDIVLGSATIAA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A_PETCR
Sequence: METAGKAKKGFGGRKGGPRKKSVTRSVKAGLQFPVGRIGRYLKKGRYAQRVGTGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIIPRHLLLAVRNDEELGKLLAGVTFAHGGVLPNINPVLLPKKTAEKAAKEPKSPSKAGKSPKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TGT_ARCFU
Sequence: MPLKFRIKHTLDRMRVGKVKTRHGSFETPVFIPVATLAAIRGLDNRDLKDMGVEVILANTYHLHLRPGDELIKELGGLHKFMNFDGVIVTDSGGFQAFSLGFGMEHGVGKIANNIFLEELREERLREAENERKKLAVVTDRGVRFKDPKSGRIVELTPKKSMEIQSNLGSDIIFAFDECTSPLSDRDYTEKALERTHRWAEECLQHYDRRQALFGVVQGGEYRDLREKSARFMAERDFAGYGIGGSLGKSKQDMLNILDWVIPLLPEEKPRHLLGIGAIEDLFNCTEKGVDMYDCVAPARWARRGHLYVSPAEGGNVRNKFRIHIKNAAFRIDNRPVDRTCDCLVCQNYSRAYLRHLYKANELLYFRLATYHNIYFVVKLMERIRESIADGSFYELKREWLGF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Putative queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DAC_ACTSP
Sequence: MKQSSPEPLRPRRTGGRGGARRAAALVTIPLLPMTLLGASPALADASGARLTELREDIDAILEDPALEGAVSGVVVVDTATGEELYSRDGGEQLLPASNMKLFTAAAALEVLGADHSFGTEVAAESAPGRRGEVQDLYLVGRGDPTLSAEDLDAMAAEVAASGVRTVRGDLYADDTWFDSERLVDDWWPEDEPYAYSAQISALTVAHGERFDTGVTEVSVTPAAEGEPADVDLGAAEGYAELDNRAVTGAAGSANTLVIDRPVGTNTIAVTGSLPADAAPVTALRTVDEPAALAGHLFEEALESNGVTVKGDVGLGGVPADWQDAEVLADHTSAELSEILVPFMKFSNNGHAEMLVKSIGQETAGAGTWDAGLVGVEEALSGLGVDTAGLVLNDGSGLSRGNLVTADTVVDLLGQAGSAPWAQTWSASLPVAGESDPFVGGTLANRMRGTAAEGVVEAKTGTMSGVSALSGYVPGPEGELAFSIVNNGHSGPAPLAVQDAIAVRLAEYAGHQAPEGARMMRGPVQGSGELECSWVQAC
What is the function of this protein?
Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
What are the official names of this protein?
D-alanyl-D-alanine carboxypeptidase, DD-carboxypeptidase, DD-peptidase, Penicillin-binding protein, PBP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENGB_WOLSU
Sequence: MITVVESSFLTSASALSQTPPPKNSEVVFIGRSNVGKSTLINLIVDSKGLAKSSSTPGKTQLINYFETIWKRGEERIPLWLVDLPGFGYAKVSKEMRKDWGEKLIHFLQERRSIKLFVQLIDARHPDLAIDAEAWAMIGAIKRGDQKVIRVFTKMDKLNRNDQKKLQQRYPDACFTAMLGKEGIASVRERVLKDVLGEEA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RL12_AERPE
Sequence: MAQEGKAYIHLALAIYYAGGKIDEETLKKAAEAIGMQVDEAKIKMLVASLEEVNLEEVLKQAVAAPVAAAAAAPAAAPAAEEKAEEEKKEEEEEKKEEEVDLSGLSGMFGF
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: FABZ_KLEP3
Sequence: MTTDTHTLHIEEILELLPHRYPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_BURP1
Sequence: MLYPTEFDVIVVGGGHAGTEAALASARMGAKTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAAATDEGGIQFRILNSSKGPAVRATRAQADRVLYKQAIRRRLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGVRFRARAVVLTAGTFLDGKIHVGLNHYTGGRAGDPAAVSLSSRLKELNLPQGRLKTGTPPRIDGRTIDFSKLDEQPGDLDPIPVFSFLGRAEQHPQQLPCWVTHTNERTHDIIRSGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEPEGLTTNEFYPNGISTSLPFDVQLALVHSMRGLEQAHILRPGYAIEYDYFDPRALKSSLETKAIGGLFFAGQINGTTGYEEAAAQGLLAGINAGRYAQEKDAWCPRRDQAYLGVLVDDLVTRGVSEPYRMFTSRAEYRLSLREDNADMRLTEVGRELGVVDDVRWDAFNRKRDAVSRETERLRTTWVTPKTLPADEATALLGKPIDHEYSLAELLRRPGVSYDGVCGLRGGECGPSEPLAEDELLLAQIKEQIEIGIKYQGYIERQAGEIERNGANENTRLPDGIDYTEVRGLSFEVSQKLNQFRPETIGQASRISGMTPAAISLLMVHLKKRGLGRRKGADSVPGADVQADNTAAQQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_YERPE
Sequence: MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDENDKMNLNVQQAGGSVLVVSQFTLVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKTETGLFAADMKVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBBB_CATCL
Sequence: VEWTDAERGAILSLWGKIDPDELGPALLARXXLVYXXTQRYFASFGDL
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-B, Beta-B-globin, Hemoglobin beta-B chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ATCL_MYCGE
Sequence: MNSWTGLSEQAAIKSRQEHGANFLPEKKATPFWLLFLQQFKSLVVILLLLASLLSFVVAIVSGLRSNWNFNHDLIIEWVQPFIILLTVFANSLIGSIQEFKAQKSASALKSLTKSFTRVFRNGELISINVSEVVVGDIIFVDAGDIIPADGKLLQVNNLRCLESFLTGESTPVDKTIDSNEKATILEQTNLVFSGAQVVYGSGVFQVEAVGIKTQVGKIAKTVDDSVTKLSPLQQKLEKIGKWFSWFGLGLFAVVFLVQTALLGFDNFTNNWSIALIGAIALVVAIIPEGLVTFINVIFALSVQKLTKQKAIIKYLSVIETLGSVQIICTDKTGTLTQNQMKVVDHFCFNSTTQTDLARALCLCNNASISKDANKTGDPTEIALLEWKDRSQLDLKTYYRVYEKAFDSIRKLMTVVVQKDNRFIVIVKGAPDVLLPLCNNVQNEVKNIENLLDQSAGQGLRTLAVALKVLYKFDQNDQKQIDELENNLEFLGFVSLQDPPRKESKEAILACKKANITPIMITGDHLKTATVIAKELGILTLDNQAVLGSELDEKKILDYRVFARVTPQQKLAIVSAWKEAGFTVSVTGDGVNDAPALIKSDVGCCMGITGVDIAKDASDLIISDDNFATIVNGIEEGRKTFLTCKRVLLNLFLTSIAGTVVVLLGLFILGQVFKTNLLQQGHDFQVFSPTQLLIINLFVHGFPAVALAVQPVKEKLMVGSFSTKNLFYNRQGFDLIWQSLFLSFLTLLFYSLGIIYAINNRDLQTSGDLINRAGSTCGFFILGASAALNSLNLMVDKPLLMTNPWFFKLVWIGSLASILVFLLIIFINPLGLVFNVLQDLTNHPVLISYSFGGVILYMGMNEVVKLIRLGYGNI
What is the function of this protein?
Could mediate calcium influx.
What are the official names of this protein?
Probable cation-transporting P-type ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type II subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL1_ENT38
Sequence: MAKLTKRMSVIRDKVDATKQYDITEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPNGTGRSVRVAVFAQGANAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDTEKLKENLESLLVALKKAKPTQAKGVYIKKISLSTTMGAGVAVDQAGLTAVAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RL5_BRASO
Sequence: MAETAYTPRLRTEYDRKIKSALTEKFGYANVMQVPRLDKVVLNMGIGEAVNDRKKAETAAADLSLIAGQKAVVTYSRVAIATFKLRENQPIGCKVTLRKAKMYEFIDRLINVALPRVRDFRGLNPKSFDGRGNYSLGIKEHIIFPEIDFDKAGESWGMDITVCTTATTDDEARALLTAFNFPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GLPK_LACLA
Sequence: MTETSYIMAIDQGTTSSRAIIFDKHGKHIGSSQKEFTQYFPKEGWVEHDANEIWNSVQSVIAGAFIESGIKPVQVAGIGITNQRETTIIWDKKTGKPIYHAIVWQSRQSADIANGLKEAGHEELFHKKTGLIVDSYFSATKIRWILDHVEGAQERAERGELLFGTIDTWLLWKLTDGDAHYTDYSNASRTMLYNIHELKWDEEILKILNIPASMLPEVKSNSEVYGVTKGFHFFGSEVPISGMAGDQQAALFGQMAFEPGMIKNTYGTGSFIVMNTGEKPHISKNNMLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLKMLERASDSEEVALQSRSQDEVYVVPAFVGLGAPYWDQEARGAMFGLTRGTTKEDIVKATLQGIAYQVRDVVSTMKEDTGIDMSVLKVDGGAANNEYLMQFQADILNIPIQRAGDLETTALGAAFLAGLAVGFWKDLEELKESYEPGKIFQTQMQEERREELYAGWKKAVNATRAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: ATP6_VIBC3
Sequence: MAAPGEALTPSSYITHHLTNLSTYKLGLVAEESSFWNVHIDSLFFSVLTGLIFLGVFRAVARKATAGVPGKLQCAVEMVVEFVDKNVKDTFHGRNPLIAPLALTIFCWVFLMNLMDLVPIDFLPYPAQHWLGIPYLKVVPSADVNITMAMALGVFALMIYYSIKVKGLGGFAKELALHPFNHWIMIPFNLLIEVVSLLAKPLSLGMRLFGNMFAGEVVFILCAAMLPWYLQWMGSLPWAIFHILVILIQSFVFMMLTIVYMSMAHEDNDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THRSP_HUMAN
Sequence: MQVLTKRYPKNCLLTVMDRYAAEVHNMEQVVMIPSLLRDVQLSGPGGQAQAEAPDLYTYFTMLKAICVDVDHGLLPREEWQAKVAGSEENGTAETEEVEDESASGELDLEAQFHLHFSSLHHILMHLTEKAQEVTRKYQEMTGQVW
What is the function of this protein?
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland.  Important for the biosynthesis of triglycerides with medium-length fatty acid chains.  May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity).  May function as transcriptional coactivator.  May modulate the transcription factor activity of THRB.
What are the official names of this protein?
Thyroid hormone-inducible hepatic protein, Spot 14 protein, S14, SPOT14.
What is the protein family that this protein belongs to?
Belongs to the SPOT14 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TCHP_HUMAN
Sequence: MALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAERRLQAWEADQQEEEEEEEARRVEQLSDALLQQEAETMAEQGYRPKPYGHPKIAWN
What is the function of this protein?
Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress.  Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation.  May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery.  May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701).  Is a negative regulator of ciliogenesis (PubMed:25270598).
What are the official names of this protein?
Trichoplein keratin filament-binding protein, Protein TCHP, Mitochondrial protein with oncostatic activity, Mitostatin, Tumor suppressor protein.
What is the protein family that this protein belongs to?
Belongs to the TCHP family.
Protein: CP2A7_PAPSP
Sequence: MLASGLLLVALLACLTVMVL
What is the function of this protein?
Exhibits a high coumarin 7-hydroxylase activity.
What are the official names of this protein?
Cytochrome P450 2A7, CYPIIA7, Coumarin 7-hydroxylase, Cytochrome P450 FI.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: NINH_BPH19
Sequence: MTFTVKTIPDMLLEAYGNQSEVARILNCNRATVRKYIGDKEGKKHAVVNGVLMVHRGWGKDTDA
What are the official names of this protein?
Protein ninH.
What is the protein family that this protein belongs to?
Belongs to the ninH family.
Protein: KKQ8_YEAS7
Sequence: MVMQEEKKRQQPVTRRVRSFSESFKNLFRPPRSRDSSPINVTRIPYRSSSTSPKRSSEPPRRSTVSAQILDPKNSPIRQRSYTLKCCTPGLSHPFRQTGSGASNSPTRHRSISGEEQEIVNSLPEYKRSASHTFHGIRRPRSRSSSVSSCDSSNGTTSSSDSQWAMDSLLDDSDNDLTPYRGSNKDILKSKDRAPYNYIDDYNKKALRRATSYPNPLPSKQFYNERLYTRRSHPDEESLESLPRSAGADVQCIIEQNGFKVYEDGSHEHNIKLSGVIAKLEKGNSLPVHRQGLLSRPRLGITLSGLFKHHKNECDIENASSLLPNVEKSQTNHEKRTGQSPNDSNRSSPTQGREDYLKIVNPDASLGSDELKLINSLSSRIHKSLQNYLQEKNLKPAECIGEQAPTFQDNYGHPVGLVGAGAYGEVKLCARLRNEKDSPPFETYHDSKYIYYAVKELKPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHHLWKVASREKDMSYDEFYKEMQRKNQFRVFEELKHVNSELATNRKIALYRIFQWEPRKRISVGKLLDMQWMKSTNCCLIYDST
What are the official names of this protein?
Probable serine/threonine-protein kinase KKQ8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NPR/HAL subfamily. HAL5 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_STAS1
Sequence: MTNALLEDLKWRGLIYQQTDESGIENILNKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPLVLIGGGTGMIGDPSGKSEERTLQTEAQVETNVQGINKQMHKIFEFDTEKGAKLVNNKDWLGQISLIDFLRDYGKHVGVNYMLGKDSIQTRLEHGISYTEFTYTILQAIDFGHLNRTYNCKVQVGGSDQWGNITSGIELMRRMYGQTEAYGLTIPLVVKSDGKKFGKTEGGAVWLDAAKTSPYEFYQFWINTTDDDVIKFLKYFTFLEQEEIEALEKSLNEAPHLREAQKALAENVTRFIHGQDALDDAIRISQALFAGDLQSLSASELKEGFKDVPQVELSSETRNIVEVIVETGISSSKRQAREDVNNGAIYINGIRQQDVNYELTSEDKIENEFTIIRRGKKKYFMVNYK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNT_SALPB
Sequence: MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRTGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLYHSQKYLLPAFCPLGLALLFGFSIPDRVMESKQPQFFVEMTQAPLASSRYILADNVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQDKFVKADDFNAWLNQHRQEGIITLVLSIAKDENISALSLPPADNIDYQGRLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURE_CHLTA
Sequence: MHLDQLLQNIPAKIYGKVESIPVRNLTRDSRCVGVGDIFIARQGQFCNGNDYSSQAVANGAIAVLSSLYNPFLSVVQIIAEDPIALEASLAARFYNNPSRHLDVIGITGTNGKTTVSCLVRELMERSGRRTGLIGTIEHILGENRIIDSFTTPDAILLQKYFAEMVKQNLSAAVMEVSSIGMALGRVRETEFLAGVLTNITSDHLDFHGSLEEYIAAKKQFFASLPEKGIAVVNLDCEYAPSFLNGSQARAVSYAIHQEADYRADRLKLYSSGSSYDIWYQGQVFPCETSLIGEHNVYNVLASLAVVHQFLGRDFADLVRDVRFLSAPKGRLDPILLGPFPVYIDYAHTPDALDNVCRILLQLLPKDGRLIIVFGCGGDRDRVKRPLMAKVSEHYGFSFVTSDNPRTEDPDQIIADICKGFSTDHYVVESDRKLAIEKAISMASDKDIVLVAGKGHEGYQIFKHQTIVFDDREVVCEALAALC
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_XANC5
Sequence: MPFLELTLSCSEVTLPRFQNALDDVGALAVTMLDADADTSNERAILEPGVGEMPLWDRLTMTALFDGDSDALVVLAALEAFDPGLDWSQVAFRMVEDSDWERAWMDLFKPMQFGERTFIVPWNHALPEAADTPEAAVVRLDPGLAFGSGTHQTTALCLRWLDSLAGSGELQGRSVLDFGCGSGILAVAALKLGAAGAVGVDNDPQALLATADNAQRNGVDAQLTVYMPQDEPVQTYQVVVANILASALDALADTLAARVAPGGRIALSGILHGQEDDLLKRYAPWFDQLRCERDEDWMRIDGVRRG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_PSEP1
Sequence: MDMQSRIRRLFEASIETKQQAMDILAPHIEQASLVMVNALLNEGKMLACGNGGSAGDAQHFSSELLNRFERERPSLPAIALTTDSSTLTSIANDYSYNEVFSKQIRALGQPGDVLLAISTSGNSANVIQAIQAAHDREMIVVALTGRDGGGMASLLLPEDVEIRVPSTVTARIQEVHLLAIHCLCDLIDSQLFGSEE
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPP1_SCHPO
Sequence: MEAVGKHVKLFWNVYSDYAVLIAISLSYFVFDVLMLPFTRQFSLEDITISHPFALHEQVPTKYLGIICVFFPALVLYGFGKLRNNSLLFWKSLMGLLYSTMVCGLCVSLLKNAVGRPRPDFLARCQPFESTPKTGLVDVLSCSVPWSDKVLQDGFRSFPSGHTSFSFAGLGFLAIFLAGQLKMFRNKTSSWKVVVPLVPLSIASWIGLSRSQDYRHHKEDIAVGALFGFAIAYVVYRQLFPPLDHHNADILYVQAELDEGYTNVHSAGNSSATNAEQMV
What is the function of this protein?
Catalyzes the dephosphorylation of diacylglycerol phosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (DAG).
What are the official names of this protein?
Probable diacylglycerol pyrophosphate phosphatase 1, DGPP phosphatase, Phosphatidate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: VE2_HPV56
Sequence: MVPCLQVCKAKACSAIEVQIALESLSTTIYNNEEWTLRDTCEELWLTEPKKCFKKEGQHIEVWFDGSKNNCMQYVAWKYIYYNGDCGWQKVCSGVDYRGIYYVHDGHKTYYTDFEQEAKKFGCKNIWEVHMENESIYCPDSVSSTCRYNVSPVETVNEYNTHKTTTTTSTSVGNQDAAVSHRPGKRPRLRESEFDSSRESHAKCVTTHTHISDTDNTDSRSRSINNNNHPGDKTTPVVHLKGEPNRLKCCRYRFQKYKTLFVDVTSTYHWTSTDNKNYSIITIIYKDETQRNSFLSHVKIPVVYRLVWDK
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.