PharMolix/UniProtQA huggingface dataset:
Protein: CBP4_ASPNC
Sequence: MSRAGTWMKMLGVGIVICVGGPAFVQYIRPTDEELFKRYNPDLQKRSLEEGDRRAREFDEYVTRLKQWSKSDKSIWYAAQEQQEQKRVEAEVQRNQARDDAKVQREEMRKELLGEK
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor cbp4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RBSA1_THEMA
Sequence: MFPLLAFRGDRMEILKAKGIVKRFPGVVAVDNVDFEVYENEIVSLIGENGAGKSTLIKILTGVLKPDAGEILVNGERVEFHSPVDAFKKGISVIHQELNLCDNMTVAENIFLAYEAVRGQKRTLSSRVDENYMYTRSKELLDLIGAKFSPDALVRNLTTAQRQMVEICKALVKEPRIIFMDEPTSSLTVEETERLFEIIEMLKSRGISVVFVSHRLDEVMRISDRIVVMRDGKRIGELKKGEFDVDTIIKMMVGREVEFFPHGIETRPGEIALEVRNLKWKDKVKNVSFEVRKGEVLGFAGLVGAGRTETMLLVFGVNQKESGDIYVNGRKVEIKNPEDAIKMGIGLIPEDRKLQGLVLRMTVKDNIVLPSLKKISRWGLVLDERKEEEISEDYVKRLSIKTPSIYQITENLSGGNQQKVVLAKWLATNADILIFDEPTRGIDVGAKAEIHRMIRELAAQGKAVIMISSELPEILNLSDRIVVMWEGEITAVLDNREKRVTQEEIMYYASGQKKQNGRVA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CLPX_RHIL3
Sequence: MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSRDGVPTPQDIIKVLDEYVIGQRQAKKILSVAVHNHYKRLAHASKNGEVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDKIISARGEKTSIGFGASVKSQDDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDEDALIQILSEPKNALIKQYQRLFEMEDVELNFHEDALREIARKAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEEVVRGSARPLYIYADRQEEKANASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: HYPA_HELHP
Sequence: MHEYSIVASLIQMCESHAKEHNAASIAKVCIAVGERSGVDSALVKSAFETFRLDSPLCQNTILEIQSQSVELECRDCGHYFQAQNLTYSTCPQCQSHNVIIAKGKELHLLSLELDIQS
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: NEMO_BOVIN
Sequence: MSRPPWKSPLCEMVQPSGSPAGDQDMLGEESSLGKPAMLHVPSEQGTPETFQRCLEENQELRDAIRQSNQMLRERCEELQHFQGNQREEKAFLMQKFQEARDLVVRLSLEKRELRQQREQALKEVERLKTCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQALESRARVASEKARQLESEREALEQRHSVQVDQLVLQNESMEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHMKSSMVSSERNRGLQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKEFLQEQLEQLQREYSRLKTSCQESARIEDMRKRHVEVSQPPLAPGPAHHSFHLNPSSQRRSPPDEPPKFCCPKCQYQAPDIDTLQIHVMECIE
What is the function of this protein?
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor.  Its binding to scaffolding polyubiquitin plays a key role in IKK activation by multiple signaling receptor pathways.  Can recognize and bind both 'Lys-63'-linked and linear polyubiquitin upon cell stimulation, with a much highr affinity for linear polyubiquitin.  Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity.  Essential for viral activation of IRF3.  Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
What are the official names of this protein?
NF-kappa-B essential modulator, NEMO, IkB kinase-associated protein 1, IKKAP1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma, NF-kappa-B essential modifier.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress.
Protein: URK_VIBVU
Sequence: MSEKSQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYNDQSHLSMEERVKTNYDHPNALDHDLLCEHLEKLMKGESVEVPEYSYTEHTRTENTTTMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVEERGRTMESVLKQYQKTVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKA
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1649_METJA
Sequence: MVMILIKLEIDRRAYNSIKNFSRLVYTKAIKNRGDLPKKEEIVTLTYNGKFVAKALYNPKSVILKILTTEDEEIDYDFFYKRIFNAKIYRENILNYKNTYRWIYAEGDELPTIIFDKYNELGAMQLMSKLIEKEYLKDIVDILFELSDLETIYVKRGKKGERIRDKIFGDKNKFETVIKEGDAKFKVNVRGHKTGFFLDQRENRLYLEKFIKEGDRVLDICCYTGGFSVHAAIRGAEVVGVDLSKKALKLAEENIELNNIPKDRYEFIEGNAFEVMKEMIEDKEKFDVVILDPPAFTQTEDDIKNALRAYASLNYLGIKLAKRIFVTCSCSHHVDKEMFKRTVISSAFRAKKELIMIDYKGQAPDHPISIGNKNLEYLKCIFFYVKN
What are the official names of this protein?
Putative ribosomal RNA large subunit methyltransferase MJ1649.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCMF1_DROME
Sequence: MSRHEGVSCDSCLKSNFNGRRYKCLICYDYDLCADCYEDGVTSTRHLVEHPMQCILTRSDIELYFGGEMLASDQPQSFTCPYCKKMGFSDATLLEHVSAEHTETSLEVVCPVCAGLPGGEPNLVTDDFAGHLTLEHRQGPRELISFLDEPSAIRHGGGVRRIPGRTLGGPRTRRSNMHFSSSSGLSALSPSGRESVDPIAELLSQLSGVRRGGPPTSQLQQLQMQMQLDRQQVTASRQIDRLPRRAHPIVSTSNSNAAMAEVISGGAGGSGGSGAVGSGSGGGSGATAPPNLRTTEWPVTASFSTSASNHSQTQSSLAANSLNAREAIGTSSSAGSNVLGISVGVGGTANGNGGAGSSGVATGAGGAGQGGGQGGAAAGESFLLAQFMQPTFTEAEWAVVESMRADRSMFVQSLMLSMLCTEALDLNASDESLAKSDNVNKGQQQQQEDAEAEAQAETLLNNNADVEQQQQQQQLQPAMVRQVNQMQQTSPEDFVCDEYRYKNKKANTTQTSGTGGLGGAGATAAPGGGASGAGTKPTADRGIERRSGRPPPGEMATGSQQPQQQQQSTANPAASQQKYKQNASAATAAGNTNQIPDTR
What is the function of this protein?
Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.  Involved in the negative regulation of the Ras/MAPK signaling pathway in the wing by acting with the E2 enzyme Unc6 and the putative E3 ligases poe and Ufd4 to mediate the ubiquitination and proteasomal degradation of rl/MAPK.
What are the official names of this protein?
E3 ubiquitin-protein ligase Kcmf1.
What is the protein family that this protein belongs to?
Belongs to the KCMF1 family.
Protein: MNME_ORITB
Sequence: MTSKTIFAQSSAKGKAGVAVFRISGSLSLLIVERLCGKFNIVPRKVYYRTIRCYATSQVIDKALIVYFKGEQSFTGEDVVEIHTHGSVAVAKMLTRSILECDGIRLAEPGEFAKRAFLNGKMDLTMAEGLVDLIESETLMQHKQAIRQMEGELEKLYSHWRGMLIKILSFIEGYIDFPDEEIPQSVLREAKSIINNLTREISNHLGDTRKGEVLRHGIVLAITGETNTGKSSLLNYLTMREAAIVSDIPGTTRDVIEAHLDIGGYPIIVRDTAGIRESDDPIEQEGIKRSLVAFKNSDIRILMIDATNINSVNQTIAHLLNDVYTIIVINKIDLVNYKYDSSILPCDKPIVAVSLLKQVGLDRLMSEIVSYAEKIADPGNVPAITRERYRNSLNKALELLQLVNLENDLVLAAEDLRMAIRYLEHITGKIKIDDILAEIFASFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTPA_ERWP6
Sequence: MSTANKHPEAASLNAFKQPRSFYLIFSIELWERFGYYGLQGIMAVYLVKMLGMSEAQSITLFASFSALVYGLIAVGGWLGDKVLGTKRVIVLGTLVLALGYALVAWSGHDIAMIYFGMATIAVGNGLFKANPSSLLSTCYEKDDPRLDGAFTMYYMAINIGSFFSMLATPWLAAQFGWSTAFGLSFVGMLITLVNFMFFRKWVKDHGSKPDFAPLNMGKLLVTLLGIAVMIAAATWLLHNQDIARMVLGAVAVAIVVIFTKEALTLKGAARRKMIVAFLLMLEAIVFFVLYMQMPTSLNFFAIRNVEHSLLGIAFQPEQFQALNPFWIMIFSPLLAALYNKLGDRMPMPHKFALGMVLCSAAFLVLPLGASLANKMGIVSVGWLVLSYALQSVGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGAAMVAGKVANLMAVPENITNPLLSLHVYGDIFFKIGITTGVIAVLMILAAPLLNRMTQDEQPGV
What is the function of this protein?
Proton-dependent permease that transports di- and tripeptides.
What are the official names of this protein?
Dipeptide and tripeptide permease A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y6114_BACAN
Sequence: MSTILVLGGSNGRTLEKLAKKRDCQVIFHDGKNHGGVKKTFRSVIKKCDVIVIQKGACGHVSIDVAKEYAKKYDVPLLFNQGFGGTGALEMGLKHLKAA
What are the official names of this protein?
UPF0751 protein pXO1-84/BXA0114/GBAA_pXO1_0114.
What is the protein family that this protein belongs to?
Belongs to the UPF0751 family.
Protein: MURG_KLEP3
Sequence: MSGQEKRLMVMAGGTGGHVFPGLAVAHHLMDQGWQVRWLGTADRMEADLVPKNGIEIDFIRISGLRGKGIKAQLLAPVRIFNAWRQARAIMKRFQPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIAKKVMQAFPGAFPHADVVGNPVRTDVLALPLPGQRLVGRHGPIRVLVVGGSQGARVLNQTMPQVAAKLGDAVTIWHQSGKGGQQTVQQAYAAAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKILEQPEFTVEAVASTLASWDRETLLDMAERARGASIPDATERVAEEVSAVALAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HSP1_DENGO
Sequence: MARYRHSRSRSRSRYRRRRRRRSRYRSRRRRYRGRRRRRSRRGRRRGYSRRRYSRRRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL29_DESAH
Sequence: MKISEIREMSAQEITGKLTELKKEFFNLRFQHGVGQLENTAILPSIRKDIARLMTVCREMNLNIS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ARP1_ASPFU
Sequence: MVEKKPNLTLEFHDYLALKKVLFDWADSYDAKDWDRLRSIIAPTLTVDYRQIGLRKWDDMPAEDYMAMISDMDFLGDPTVKTQHLLGESWWEKISDTEVIGHHQLRAAHQVYTDSTLQTVKLKGHGHATNEHYYRKVDGVWKFAGLKPTVRWNEYQFEDVFRAAKPSV
What is the function of this protein?
Scytalone dehydratase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall (PubMed:10515939, PubMed:19156203).  The first step of the pathway is the production of the heptaketide naphtopyrone YWA1 by the polyketide synthase alb1 though condensation of acetyl-CoA with malonyl-CoA (PubMed:10515939).  The naphtopyrone YWA1 is then converted to the pentaketide 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN) by the heptaketide hydrolyase ayg1 though chain-length shortening (PubMed:10515939).  1,3,6,8-THN is substrate of the hydroxynaphthalene reductase arp2 to yield scytalone (PubMed:10515939).  The scytalone dehydratase arp1 then reduces scytalone to 1,3,8-THN (PubMed:10515939).  1,3,8-THN is also substrate of the hydroxynaphthalene reductase arp2 to yield vermelone (PubMed:10515939).  Vermelone is further converted by the multicopper oxidase abr1 to 1,8-DHN (PubMed:10515939).  Finally the laccase abr2 transforms 1,8-DHN to DHN-melanin (PubMed:10515939).  DHN-melanin biosynthesis appears to be initiated in endosomes where early enzymes (abl1, ayg1, arp1 and arp2) localize, with exocytosis leading to melanin deposition on the cell surface where late enzymes (abr1 and abr2) localize (PubMed:26972005).  DHN-melanin is an important structural component of the outer cell wall and is required for the presence of conidial surface hydrophobins (PubMed:19703288).  DHN-melanin also plays a crucial role in fungal virulence, including a protective role against the host's immune defenses (PubMed:19156203, PubMed:20145078, PubMed:21747802, PubMed:21573171, PubMed:24818666).  DHN-melanin protects also conidia against amoeba predation (PubMed:25684622).
What are the official names of this protein?
Scytalone dehydratase arp1, Conidial pigment biosynthesis oxidase arp1.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.
What are the subcellular locations of this protein?
Endosome.
Protein: RSMA_LACLA
Sequence: MTENNIDRISNIIRTQDILRRHDFNFKKKFGQNFLTDHNILTKITQTAELSKEVNVIEIGPGIGSLTQYLLEEAAEVMAFEIDKSLIPILEETMAPYDNFTLVSADILKVDLLSEIQKFKNPNLPIKVVANLPYYITTPILMHLIESKIPFSEFVVMMQKEVADRIAASPKTKAYGSLSIAVQYYMEASVAFIVPRTVFIPAPNVDSAILKMVRREAPLVEVEDEEWFFKTMHSSFVHRRKTLMNNLQAAFGKESKPEIEKLLAQAEISPTIRGEALSIEEFAKLADALLPLKK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_VITVI
Sequence: MNVLSCSINTLKGLYDISGVEVGQHFYWQIGGFQVHAQVLITSWVVIAILLGSATLAVRNPQTIPTDGQNFFEYVLEFIRDVSKTQIGEEYGSWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGLTKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSIVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LUC7_FUSSX
Sequence: MAPFGRLYSFMPNGRVFKILAAATLNGLEIEITPYQHMVDNKTPEFRAKFPAGKVPAFEGADGLLLPESDAIAQYLAQSGPYSEQLLGRDAATSAKIRQWISFFDGEVYPHMLDLVIWRVGIAPFDQSTETKALARLEFALDVLEKHLDGRKWLVGDELTLADLTGASSLLWAFMHIIDASERKRFPSVVAWYLRTIETEEVKEVFGPPNLIDVKRVHE
What is the function of this protein?
Glutathione S-transferase-like protein; part of the gene cluster that mediates the biosynthesis of the mycotoxin lucilactaene and the lucilactaene-related compound NG-391 that act as cell cycle inhibitors with potent growth inhibitory activity against malarial parasites, moderate growth inhibitory activity against cancer cells, and no activity against bacteria and fungi (PubMed:32043422, PubMed:35484225).  Within the cluster, LUC7 and LUC8 encode proteins which are not commonly involved in the biosynthesis of secondary metabolites and are not essential for lucilactaene biosynthesis (Probable).
What are the official names of this protein?
Glutathione S-transferase-like protein LUC7, Lucilactaene biosynthesis cluster protein 7.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: SYD_THETH
Sequence: MRRTHYAGSLRETHVGEEVVLEGWVNRRRDLGGLIFLDLRDREGLVQLVAHPASPAYATAERVRPEWVVRAKGLVRLRPEPNPRLATGRVEVELSALEVLAEAKTPPFPVDAGWRGEEEKEASEELRLKYRYLDLRRRRMQENLRLRHRVIKAIWDFLDREGFVQVETPFLTKSTPEGARDFLVPYRHEPGLFYALPQSPQLFKQMLMVAGLDRYFQIARCFRDEDLRADRQPDFTQLDLEMSFVEVEDVLELNERLMAHVFREALGVELPLPFPRLSYEEAMERYGSDKPDLRFGLELKEVGPLFRQSGFRVFQEAESVKALALPKALSRKEVAELEEVAKRHKAQGLAWARVEEGGFSGGVAKFLEPVREALLQATEARPGDTLLFVAGPRKVAATALGAVRLRAADLLGLKREGFRFLWVVDFPLLEWDEEEEAWTYMHHPFTSPHPEDLPLLEKDPGRVRALAYDLVLNGVEVGGGSIRIHDPRLQARVFRLLGIGEEEQREKFGFFLEALEYGAPPHGGIAWGLDRLLALMTGSPSIREVIAFPKNKEGKDPLTGAPSPVPEEQLRELGLMVVRP
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA(Asp) ligase, Aspartyl-tRNA synthetase, AspRS, Discriminating aspartyl-tRNA synthetase, D-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y383_BACHK
Sequence: MDLSVKSEENVEYMVEAIKEKLRMVNAGAMRAASFNEEMYEDLRDIYEHVMKRETFSISEMQAITEELGTLIKK
What are the official names of this protein?
UPF0435 protein BT9727_0383.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: CECA1_DROMA
Sequence: MKFYNIFVFVALILAITIGQSEAGWLKKIGKKIERVGQHTRDATIQGLGVAQQAANVAATARG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-A1.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL21_STRM5
Sequence: MYAVLVTGGKQYRVAQGEKLRIEKLEVEVGSEIKFDNILLLGDSDGIKIGDALSGAAVTATVLSQGRADKVRIIKFRRRKHHMKRQGHRQYYTEIEITGIAGGSK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: MCP_SAISC
Sequence: MAPPSRRECPFPSRRFPGLFLAALALLLSSRSDACGPPPTFVAMELTSRPKPYYKVGEQVEYDCKKGYHHFAPFLTHTVCDRNHTWLPISDAPCVKKVCHYIPNPAHGQAILANGTYSFGNQLHFICNDGYYLIGKAILYCELKGSDAVWSGRPPICQKILCKPPPTIKNGKHTFSEVDVFEYLDAVTYSCDPAPGPDPFSLVGESTIYCRDSLGWSGDPPECKVVKCRFPVIENGRQTAGFGIKFYYNAAVMFECYEGFHIIGSDTIVCNSNSTWDPPVPKCVK
What is the function of this protein?
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue.  May be involved in the fusion of the spermatozoa with the oocyte during fertilization.  Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells.  T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity).
What are the official names of this protein?
Membrane cofactor protein.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Inner acrosomal membrane of spermatozoa.
Protein: RUTD_ECOCB
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSITQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDHPASVTVLVCVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: ATPA_CHLCH
Sequence: MSTTVRPDEVSSILRKQLANFESEADVYDVGTVLQVGDGIARVYGLTKVAAGELLEFPNNVMGMALNLEEDNVGAVLFGESTMVKEGDTVKRSGILASIPVGEAMLGRVINPLGEPIDGKGPIDAKLRLPLERRAPGVIYRKSVHEPLQTGLKAIDAMIPVGRGQRELIIGDRQTGKTAVALDTIINQKGKGVFCIYVAIGLKGSTIAQVVSTLEKYDALSYTTVIAATASDPAPLQFIAPFAGATLGEYFRDTGRHALVIYDDLSKQAVSYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAAKITDDVEVAKKMNDLPDALKPLVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESNLFNSGQRPAINVGISVSRVGGAAQIKAMKKIAGTLRLDLAQFRELEAFSKFGSDLDKTTKAQLDRGARLVEILKQGQYVPMPVEKQVAIIFVGTQGLLDSVDLKFIRKCEEEFLAMLEMKHADILSGIAEKGTLEADVASKLKDIATKFIATFKEKNKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPGP2_HUMAN
Sequence: MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGPEEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDKLSHASSGAGH
What is the function of this protein?
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
What are the official names of this protein?
Rap1 GTPase-activating protein 2, Rap1GAP2, GTPase-activating Rap/Ran-GAP domain-like protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region.
Protein: HBA_SPECI
Sequence: VLSPADKKNVKDCWEKIGGHGAEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVQGHGKKVADALANAAAHVDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHHPAEFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.