PharMolix/UniProtQA huggingface dataset:
Protein: ACR5_CAEEL
Sequence: MLPNIILILLIRYCSCGAGSRVYEKYGKQVQLSPATTSSYREWYDSNREHSTRNNTNVDDFQTQLKKSLENTTAAYNATFMQELIEERQRYLEKLNEGQFINDQRRLVEELLDPNYYEKTVHPKRDYTRPTRVNLSMSLYQILDVDEHMQSIEVNVWMVQHWYDEFLDWNPVDYGMINRTIVPYHQIWIPDTYLYNSEELEQKKTESLMNAQLETGHWNQKKDGAKVQLMFPAIYKLSCRMDVRWFPYDRQNCTFIISSWTHDKQTIDYWPLSSTVNLGNMARNDEWEVISFEFVRVEETFKCCTAPWVMLYAHLVIRRKPLYYMINLVVPTSIITIVAVTGFFTPTSSSSERDEKLYLGINTLLTMSVMMLMVCNQMPSTSTYVPLMSWYYIGIIMVIVVGTFLATGVLAIHGQKHYNKPISDRIRKLIYNPVVEFFILSPPTSLIDLWTEFGVISEQRHSTHLDPLLLQHMDPISHTTRADPQHFFGSISSQMCDLQSTYSYTARLATITRQYTQHAKMKALRKNQYRMSMDTSQARGVKKQKMQRRCSLEWEFLANVLDRILLTIFCGFTFAVFIILIGFDSFFTFHTDSPPKTM
What is the function of this protein?
Subunit of nicotinic acetylcholine receptor (nAChR) (PubMed:23351035).  Involved in nAChR sensitivity to nicotine (PubMed:23351035).  Modulates locomotion towards the drug nicotine (PubMed:23351035).
What are the official names of this protein?
Acetylcholine receptor subunit alpha-type acr-5.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: SYGA_HELP2
Sequence: MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQVVIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIACSPIPVEITYGLERLAMYVQKVENILEIEWAKKDNDSVRYMQVHLESEYEFSKYHFEAASVKRLLEMFKNAQAEALHCLENKLPLPAYDFVMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCALLYKEQEEEREERLKNALTKA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_GEOKA
Sequence: MQRSLKWFASATTLAMLFVLIGGALVTKTGSGMGCGRSWPLCNGQWVPDHITPELIIELSHRLVSGLAGIMVLILSIWAWRAIGHVQETKFLAVISFVFLVLQGLIGAAAVVWGQSDFVLALHFGISLISFAAVLLLTLLIFEIDKTFSAASLSLDGKMRFHIYGITIYSYIVVYTGALVRHTNASLACPSWPLCAKTRLLPVQFHEWVQMGHRLAAAVIIIWIAAAAIHAVRHYRRQPVIYYGWLIALLLVLAQMTTGALVVFTQLNLYIALAHAFFISCLFGVLSYLLLLALRTRRAPVKAADHSAGEAAPATLK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DF278_ARATH
Sequence: MSLVYMYMYIGVVMSARIQESTNDILKPITCNTNADCAKFCKGPIHNCVYHTCQCVPGNPHCC
What are the official names of this protein?
Defensin-like protein 278.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PEMT_HUMAN
Sequence: MTRLLGYVDPLDPSFVAAVITITFNPLYWNVVARWEHKTRKLSRAFGSPYLACYSLSVTILLLNFLRSHCFTQAMLSQPRMESLDTPAAYSLGLALLGLGVVLVLSSFFALGFAGTFLGDYFGILKEARVTVFPFNILDNPMYWGSTANYLGWAIMHASPTGLLLTVLVALTYIVALLYEEPFTAEIYRQKASGSHKRS
What is the function of this protein?
Produces a higher increase in the level of PC species containing long chains with three double bonds than isoform 1.
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PEAMT, PEMT, PEMT2, Phospholipid methyltransferase, PLMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Note=localized in the endoplasmic reticulum (ER) of the liver and in a lipid metabolism-rich region of the ER known as mitochondria-associated membranes (PubMed:15927961). Adopts a topography within the ER membrane that positions both termini in the cytosol (PubMed:12431977). SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Note=Found in endoplasmic reticulum where most PEMT activity is generated and in mitochondria. SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TB1_TERAN
Sequence: MLATKMSVTFCFLLMLTTVMLPTEAKTVAGRTACTQHTSCDTPGAKYCCQNSDCCGGSEHFCASFGQCMRSF
What are the official names of this protein?
Teretoxin Tan11.1.
What is the protein family that this protein belongs to?
Belongs to the teretoxin H (TH) superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CSN12_GIBZE
Sequence: MNTTFQQFAEAHSLRNGYKLAQTLSPVPPADDPQRLMAVWRSTNSHSVKGDIKHFIKSSTAHKRKLDHDETTGWVEVYTSYWKAVSEILAGESGKSSWTKVYEAWKELTSVLIRGYNSHGFEAWTIPSLYMVGKYLRLFAIKSDEERRAKAFDTGPGASLISDDFDPETDKQLQLRDCEGHLKRIFSLCLNDRAPLEESRKWGIYFVINLLFKTYFKLNSASLSRTILKTLAVYNDKGDMPPLEMFPKSQRVTFKFYEGVLLFLEENYIKAESHLNEAWQLCHKDAYPQSERILTYLIPCRLLTSHVLPTKALLENYPRLQDLFLPLATCIKTGNLQAFDQALQRGEAEFVKRRIYLTLERGRDIALRNLLRKVFIAGGFDEAKEADAAPVRRTRIPVAEFQAAISMGSGHLVDPDEVECMLANMIYKDLMKGYIARERGIVVLSKKGAFPGTGL
What are the official names of this protein?
Protein CSN12 homolog.
What is the protein family that this protein belongs to?
Belongs to the CSN12 family.
Protein: TLK2_HUMAN
Sequence: MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
What is the function of this protein?
Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation (PubMed:9427565, PubMed:10523312, PubMed:11470414, PubMed:12660173, PubMed:12955071, PubMed:29955062, PubMed:33323470).  Phosphorylates the chromatin assembly factors ASF1A and ASF1B (PubMed:11470414, PubMed:20016786, PubMed:29955062, PubMed:35136069).  Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly (PubMed:20016786).  Negative regulator of amino acid starvation-induced autophagy (PubMed:22354037).
What are the official names of this protein?
Serine/threonine-protein kinase tousled-like 2, HsHPK, PKU-alpha, Tousled-like kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Note=Colocalizes with the cytoplasmic intermediate filament system during the G1 phase of the cell cycle. Present in the perinuclear region at S phase and in the nucleus at late G2.
Protein: RECG_STAEQ
Sequence: MSKVHLIESPYALDKIKGIGPKRLALLEELNIKSVEDLVLYLPTRYEDNTVIDLNQADDQATVTVQGEVYSSPTVAFFGRNKSKLTVHLMINHIAVKCVFFNQPYLKKKLELNSIVTIKGKWNRNKQEINGNRIFFNDQKNQEDAHLEPVYRVKEGIKQKQLRDNIRQALSDVTIHEWLTDDLREKYKLETLAYTIQTLHHPIDKQNLLRARRTYAFTELFMFELRMQWLNRLEKTSDEAIEINYDINKVKQFIDSLPFELTDAQKVSVNEIFRDLKAPIRMHRLLQGDVGSGKTIVAAICMYALKTAGYQSALMVPTEILAEQHAESLMQLFGNTMNVALLTGSVKGKKRRLLLEQLENGTIDCLIGTHALIQDDVVFNNVGLVITDEQHRFGVNQRQILREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIKTSWAKHEQYDQVLAQMSNELKKGRQAYVICPLIESSEHLEDVQNVVELYESLQSDYGNEKVGLLHGKMTAEDKDQVMQKFSEHEIDILVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSEHQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANVVEDYRMLEVARDEAAELIQSGQFFEQQYSHLREFIKQNLRHIRFD
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.
Protein: CSD_STAAC
Sequence: MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: CYBH_AZOCH
Sequence: MALEKSLETGDGQEKVRKQTAVYVYEAPLRLWHWVTALSIVVLGVTGYFIGAPLPTMPGEAMDNYLMGYIRFAHFAAGYVLAIGFLGRVYWAFVGNHHARELFLVPVHRKAWWKELWHEVRWYLFLEKVPKKYIGHNPLGQLAMFCFFVIGAVFMSVTGFALYAEGLGQGSWADRLFGWVIPLFGQSQDVHTWHHLGMWYLVVFVMIHVYLAAREDIVSRQSLISTMVGGWRMFKDDRPD
What is the function of this protein?
Probable b-type cytochrome.
What are the official names of this protein?
Probable Ni/Fe-hydrogenase B-type cytochrome subunit.
What is the protein family that this protein belongs to?
Belongs to the HupC/HyaC/HydC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RN148_MOUSE
Sequence: MLLCVSCLSVNGEMNPLGPTPSVHRSVSFWLLRLSVFLLLSLRDSKGKAIWTAHLNITFQVGNRIISELGESGVFGNHSPLERVSGAVVLPEGWNQNACSPLTNFSRPDQTDTWLALIERGGCTFTHKINLAAEKGANGVIIYNYPGTGNKVFPMSHQGTENIVAVMIGNLKGMELLHLIQQGVYVTIIIEVGRMHMPWLSHYVMSLFTFLAATVTYLFLYCAWRPRVSNSSTRRQRQLKADVKKAIGQLQLRVLQDGDKELDPNEDSCVVCFDMYKAQDVIRILTCKHFFHKTCIDPWLLAHRTCPMCKCDILKP
What are the official names of this protein?
RING finger protein 148, Goliath-related E3 ubiquitin-protein ligase 3.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y028_HAEIN
Sequence: MTIENDYAKLKELMEFPAKMTFKVAGINREGLAQDLIQVVQKYIKGDYIPKEKRSSKGTYNSVSIDIIAENFDQVETLYKELAKVEGVKMVI
What are the official names of this protein?
UPF0250 protein HI_0028.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: RF1_SHIFL
Sequence: MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_HYDCU
Sequence: MLTPEDKAAIVAEYATSEGDTGSPEVQVALLTHRITYLTEHFKSHIHDNHSRTGLLRLVSRRRKLLDYLHKKNAQRYFDLIKKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RF2_MYCUA
Sequence: MEPDRQAEIAALDSALTTVERVLDVEGLRSRIEKLEHEASDPKLWDDQTRAQRVTSELSHTQGELRRVEELRRRLEDLPVLYELAAEEEGAAAGEALTEADAEFKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGVDAADWAEMLMRMYVRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAYGTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMRVLQAKLLERKRIEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTEYEVGNPATVLDGDIDGFLEAGIRWRNRKDDD
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_SALPA
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: MTNK_YERP3
Sequence: MSRYHTFTAADAVEYARQFGQVADPQALVTADEIGDGNLNLVFKIRDTAGISRVIVKQALPYVRCVGESWPLTLDRARIEAETLLTHSQFCPQHTVKVLHHDAELAVMVQEDLSDHHIWRHELIQGNYYPQAAEQLGEYLAQTLFHTSDFYQSAQAKKAAVSRYTNPELCQITEDLFFTDPYIDHERNNFDPVLLPEVLSLRQDKALKLAVASLKHRFLSQAEALLHGDIHSGSIFVADGRLKTIDAEFGFYGPIGFDIGTALGNLLLNYCGLPGLAGPRDAAAGREQRLKDVQTVWQTFAARFLALSQEKAQDPALATEGYAAQFLQHVWRDAIGYCGSELIRRTIGLAHVADLDSIDDEEMRRACQRHALSLGRALILVAPHVDDVGGVVARIRQSPSSLTPQRC
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase, MTR kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: AZG2_PAELB
Sequence: MYVSSLLFLYASESYESFIFHFQMCYNKAHNGFMPSIFQQLKGLGEGLQWKVGISLDHQEKQTSSHEKEMTSPNSATRLIPSDWRRELLAGTVSFFAAVYIIIVNSSILADAGIPQEAGIIATILASAIGCFIMGLWGNAPLVIVPGMGINAMFTYTLVQGMGLTWQQALAAVMMSGICFFAISMTSLVEKLRTAIPASLQEAISVGIGLMLVLIGLHKGGVIASDRSSVIAVQSFADPGVLVTLATLALTCILYIRKVPGNLLLAIIGGSALAYLFKAVPSKAATGVGGSSWSSYGDLFGQLSVKGASITTLVIAVFSLTLVIVFENVGLINAQLKMSGRTERFKRVTQATSLTVILSGIFGTSPTVSTVEAAAGISAGGRTGWASIATGTLFLLSFIAMPVITLVPDQAVAPILIFIGGLMMPAVRHISFERMEEGLPAFFIIAFIPLMHSIVDGIAIGFISYALFHIAVGKWREVKPLFYIISLLFVMHFVLQTM
What is the function of this protein?
Transports adenine, guanine, hypoxanthine, xanthine, cytosine and uracil.  Transport is probably proton-dependent.
What are the official names of this protein?
Nucleobase transporter PlAzg2.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OSTA3_CAEEL
Sequence: MAKEHGAMRSVLNLIGSVMLPQDTSNCSDRHDTPSAPEFLSHLQPFQTVLLSIASFSTTIVLCLSLIHWFYVYKYVSIEKRRNKLYWLIAVFPVACSCSFIAMCVPRTAVILTCIGVLYYLMCLFVIVSLARHLFGGRESFSTCLQYDDRPIDFRSPPFCCIIPKLPTARSTEKNIRRLEWCVLQAPIVRSIIIFLDVVAVAEMREDATPYIRYSDMASLCSLLLAIFGVHTLARVTSNKLSAYCFMSMFRLVDISLLFFSAQQPMIFQNVLLRFNLISCGPLLNAQENAYFVCNFIITCEMLLLSVLATWLLAPRHNAMFDAYRPSMALSETTASLNETEQSMILDH
What is the function of this protein?
Probable transporter.
What are the official names of this protein?
Organic solute transporter alpha-like protein 3, Solute carrier family 51 subunit alpha homolog B.
What is the protein family that this protein belongs to?
Belongs to the OST-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VIRBA_BRUAB
Sequence: MTQENIPVQPGTLDGERGLPTVNENGSGRTRKVLLFLFVVGFIVVLLLLLVFHMRGNAENNHHSDKTMVQTSTVPMRTFKLPPPPPPAPPEPPAPPPAPAMPIAEPAAAALSLPPLPDDTPAKDDVLDKSASALMVVTKSSGDTNAQTAGDTVVQTTNARIQALLDSQKNTKQDAGSLGTLLHGTQTDARMASLLRNRDFLLAKGSIINCALQTRLDSTVPGMAACVVTRNMYSDNGKVLLIERGSTISGEYDANVKQGMARIYVLWTRVKTPNGVVIDLDSPGADPLGGAGLPGYIDSHFWKRFGGALMLSTIETLGRYATQKVGGGGSNQINLNTGGGESTSNLASTALKDTINIPPTLYKNQGEEIGIYIARDLDFSSVYDVKPK
What are the official names of this protein?
Type IV secretion system protein virB10.
What is the protein family that this protein belongs to?
Belongs to the TrbI/VirB10 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MNME_NEIM0
Sequence: MSDNVPTIAAVATAPGRGGVGVIRISGKNLLPMAQALCGKTPKPRVATYADFTDADGQAIDSGLLLFFAAPASFTGEDVIELQGHGGPVVMDMLLNRCLELGARLAEPGEFTKRAFLNDKLDLAQAEGVADLIDASSRSAARLALRSLKGDFSRRIHGLVEDLITLRMLVEATLDFPEEDIDFLEAADARGKLDGLRRAVDDVLANAQQGAILREGLNVVLVGAPNVGKSSLLNALAGDEVAIVTDIAGTTRDAVRERILIDGVPVHIVDTAGLRETDDVVERIGIERSRKAVSEADVALVLVDPREGLNEKTRAILDALPSELKRIEIHSKSDLHAHAAGGFGTGAETVIALSAKTGDGLDALKRTLLREAGWQGEGEGLFLARTRHVNALKAAQEELSLAALCGNHQIELFAEHLRLAQVACGEITGEFTADDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG38_BPM1
Sequence: MAVVGVPGWIGSSAANETGQRWMSQAAGQLRLGVPCWMSQFAGRSREIIHTLGADHNFNGQWFRDRCFEAGSAPIVFNITGDLVSYSKDVPLFFMYGDTPNEYVQLNIHGVTMYGRGGNGGSNSPGSAGGHCIQNNIGGRLRINNGGAIAGGGGGGGGGYWNASITRYRYRYVVGGGGGRPFGAAGGYSGGSASTAGTLTGAGIGSKPGNAIYGGNGGNVGSAGGAFGGISGSRYGGGAAGYAVIGSAPTWQNVGAIYGPRV
What is the function of this protein?
Vg38 is at the tip of the long tail fibers and serves as the phage recognition site for the cellular receptor.
What are the official names of this protein?
Receptor-recognizing protein, Protein Gp38.
What are the subcellular locations of this protein?
Virion.
Protein: HAND1_MOUSE
Sequence: MNLVGSYAHHHHHHHSHPPHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPTTAVAAAAYGPDARPSQSPGRLEALGSRLPKRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKTDGGRESKRKRELPQQPESFPPASGPGEKRIKGRTGWPQQVWALELNQ
What is the function of this protein?
Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis (PubMed:9500551, PubMed:16759287).  Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (PubMed:7791788).  Acts as a transcriptional repressor of SOX15 (PubMed:16759287).  In the adult, could be required for ongoing expression of cardiac-specific genes (By similarity).
What are the official names of this protein?
Heart- and neural crest derivatives-expressed protein 1, Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1, eHAND, Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast, Thing-1, Th1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity.
Protein: BTUF_VIBCM
Sequence: MLVIRLIACTFLFITPSLLAKPFPAERIISLAPHATEIAYAAGLGDKLVAVSEYSDYPPQALELERVANHQTINIEKILTLKPDLIIAWPAGNPPRELAKLRQLGFTIYDSQTKTLDEIADNIEALSHYSANPEVGQKAAHDFRQRLQDLRTQYASNQPIRYFYQLSEKPIITLAQGHWPSEVFSLCGGVNIFADSEVPYPQVSIEQVLVKQPQVIFTSEHAIANGHMWRAWQAELSAVQNDQVWALNADWLNRPTPRTLDAVEQVCTYLKIAQKQ
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DTD_LISMO
Sequence: MRVLLQRCYEASVSMEDEVISEIAGGLCLLVGFTHTDTPETVDYMAKKIVGLRIFEDESEKMNISLAERGGAILSVSQFTLYADVSRGKRPSFTKSAPGEKAEALYDLFNQKLAEAGFIVETGVFGAMMDVKIVNHGPVTIMLDSEEMRK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_CHLTE
Sequence: MKPEELKGKVASVIGAGKSGVSAAGLLARAGARPFLSEFGAVSPEAAATLRQLGVPFEEGGHSERVFEAALCIVSPGIPQTVPVIREMHARGIPVVSEIELASWFCPARIIGITGTDGKTTTATLLHRICAAEGERKGFRAFSVGNIGIPFSSEVPGMTAADIAVLELSSYQLEACFDFRPNIAVLTNVTPDHMDRYGGSIEAYATAKYRIHARQGAGDTLIYNHDDPILRAHFDRSEPWPFRLVRLGLRAETLDVAPGDFVSVEDGEIVVRASGSTERLMRVDEIMKPGFRGEHNLYNALSSVAAALAAGVAPETMRGVLAGFGGVEHRQELAGNACGLNWINDSKATSVNALRQALQSVPAGMVLIAGGRDKGNDYSAIADLVREKVACIVAIGESRRKIADAFRGVTPVVEAASLAEAVELARQNARPGASVLFSPACSSFDMFRDFEDRGRQFKQLVRELT
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDB5_PANTR
Sequence: METALAKTPQKRQVMFLAILLLLWEAGSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLLYEKLDREVICGATEPCILHFQLLLENPVQFFQTDLQLTDINDHSPEFPEKEMLLKIPESTQPGTVFPLKVAQDFDIGSNAVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDREERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSLYEVQVPENSPLNSLVVVVSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTGEIRLKRALDFEATPYYNVEIVATDGGGLSGKCTVAMEVVDVNDNAPELTMSTLSSPIPENAPETVVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALQIGSVSATDRDSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPGHLVDVSGTGILSQSYQYEVCLTGDSGAGEFKFLKPIIPNLLPQGASEEIGKTAAFRNSFGLN
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-5, PCDH-beta-5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.