PharMolix/UniProtQA huggingface dataset:
Protein: SYL_JANSC
Sequence: MSRYDPSMIEPKWQKAWAEAGTFTASMEGNKPKYYVLEMFPYPSGRIHIGHVRNYTMGDVIARHKKAMGHNVLHPMGFDAFGLAAENAAMDRGIHPKDWTYKNMDDMRDQMRPLGFSIDWSRDLATCDPDYYGQQQALFIDMMEAGLIDRKNAVVNWDPVDMTVLANEQVEDGKGWRSGAEVERKELTQWFFKISDYSDELLEALDGLDDWPAKVKLMQANWIGKSRGLQFAFGLVEPVGGHDRVDVYTTRPDTLLGASFVGISPDHAIAKQLESESEDIAAFCAECRKGGTTAAEVETAEKLGFDTGLKVRHPFDTAAQLPVYIANFILMDYGTGAIFGCPAHDERDLDFARKYDLPVVSTYVPIDDEGHVLPEDGGAAYVPPKPDPVRYIRGFAGEEIQSGNDAIDAAVTFCEAEGVGQGVTKFRLRDWGLSRQRYWGCPIPVVHCDACGVVPEKKENLPIELPYDVTFDVPGNPLDRHPTWRNTPCPSCGAPALRETDTMDTFVDSSWYFARFTAPHADTPTSKAEVEYWMNVDQYIGGIEHAILHLLYSRFFARAMHITGHLPRKAIEPFDALFTQGMVTHAIYKTTDAKNRPVYHYPETVDLRDGGGYLDDGTAVEIIPSAKMSKSKNNVVDPIEIIKQYGADTARWFVLSDSPPERDVEWTASGAEAAYKHLGRVWALCDRISEAARSVSEEAQPAAGEHDTALLREMHKTIRDVTNGVDSFGFNAAIAKLYAFTNTLQKSKASHKAQREAVMTLAQLMAPMTPHLSEDIWAHQGGDGLIADAPWPVANEAMLVESTVTLPIQINGKRRSEVTVAKDASKEEVEKRALADDAVVRALDGAAPKKLIVVPGRIVNVVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_HYPNA
Sequence: MPKMKTKKAAAKRFKITATGKLKHGVAGKRHRLMSHNAKYIRQNRGTSVGAKADEARVKKYLPYGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RS8_TROWT
Sequence: MTMTDPLSDMFSRIRNANQVLHKKVTVPSSRLKVSIADLLKREGYILDYSVIDEHPGQLLVIELKYGPDKSRALVGLKRVSKPGLRVYAKSSNLPEVFGGLGIAILSTSSGLLTCSQARKKGVGGEVLAYAW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PURA_ALKEH
Sequence: MAKNVVVVGSQWGDEGKGKVVDLLTEHTGAVVRFQGGHNAGHTLVIDGEQTILHLIPSGVLREGVQCLIGNGVVLAPDALLEEVQELEGKGVPARERLRISPACPLILPCHVALDKAREAARGQARIGTTGRGIGPAYEDKVSRRGIRVADLFHRERLAAKLGELLDYHNFVLQHYFHEQPIDFQDVLERCLTYADELRPMVADIGQLLQEHMDAGRDLLFEGAQGTLLDIDHGTYPFVTSSNTVAGAAATGTGIGPRDLHYVLGITKAYTTRVGSGPFPTELEDEIGDLLGERGREFGATTGRKRRCGWFDAVALRRAAQINSLSGLCITKLDVLDELETLRICIGYQCGDQLWESLPPGAELLADCEPQYIDLPGWQSSTLGVQQWDDLPENARAYLRKLEELIGVPVAIVSTGPDRKETIVLQNPFESA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLPD1_ARATH
Sequence: MQSAMALSFSQTSFTRPNHVLGSSGSVFSTPRSLRFCGLRREAFGFSTSNQLAIRSNRIQFLSRKSFQVSASASSNGNGAPPKSFDYDLIIIGAGVGGHGAALHAVEKGLKTAIIEGDVVGGTCVNRGCVPSKALLAVSGRMRELQNEHHMKSFGLQVSAAGYDRQGVADHANNLATKIRNNLTNSMKAIGVDILTGFGSVLGPQKVKYGKDNIITAKDIIIATGSVPFVPKGIEVDGKTVITSDHALKLESVPEWIAIVGSGYIGLEFSDVYTALGSEVTFIEALDQLMPGFDPEISKLAQRVLINPRKIDYHTGVFASKITPARDGKPVLIELIDAKTKEPKDTLEVDAALIATGRAPFTNGLGLENVNVVTQRGFIPVDERMRVIDGKGTLVPNLYCIGDANGKLMLAHAASAQGISVVEQVSGRDHVLNHLSIPAACFTHPEISMVGLTEPQAKEKGEKEGFKVSVVKTSFKANTKALAENEGEGIAKMIYRPDNGEILGVHIFGLHAADLIHEASNAIALGTRIQDIKLAVHAHPTLSEVLDELFKAAKVESHATTRTGDAKIKLNTNQEDRKGRRRGGDDEKQPSVSKDLKDISTRPSSFFENISVGVLSLLSLIFV
What is the function of this protein?
Lipoamide dehydrogenase is a component of the plastidial pyruvate dehydrogenase complex (PDC).
What are the official names of this protein?
Dihydrolipoyl dehydrogenase 1, chloroplastic, ptLPD1, Dihydrolipoamide dehydrogenase 1, Protein LIPOAMIDE DEHYDROGENASE 1, Pyruvate dehydrogenase complex E3 subunit 1, E3-1, PDC-E3 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: NUOK_XYLFT
Sequence: MISLGHLLALGAVLFCISLAGIFLNRKNVIVLLMSIELMLLAVNVNFIAFSRQLGDTAGQLFVFFILTVAAAEAAIGLAILVTLFRTHHTINVAEVDALKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMM_ALKMQ
Sequence: MKKMLKVGQIVNTHGIKGELKVTSLSDYLERFEELEWVYIQGYDEKYYIGNIKYRPTTVILSFEGYDNINIVEQFKGKYVLIDESQRRELPEDTFYKADLIGLDGYTVEEVYLGKLVDIIQAGSNEVYVFRDKETNKDILIPAVKEFIPEISLEKKRITVDPIEGMIE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTD1_ARATH
Sequence: MGRNVKTKAKRKNKKKAEASSSEIPSIPTRVWQPGVDTLEDGEELQCDPSAYNSLHGFHVGWPCLSFDILGDKLGLNRTEFPHTLYMVAGTQAEKAAHNSIGLFKITNVSGKRRDVVPKTFGNGEDEDEDDEDDSDSDDDDGDEASKTPNIQVRRVAHHGCVNRIRAMPQNSHICVSWADSGHVQVWDMSSHLNALAESETEGKDGTSPVLNQAPLVNFSGHKDEGYAIDWSPATAGRLLSGDCKSMIHLWEPASGSWAVDPIPFAGHTASVEDLQWSPAEENVFASCSVDGSVAVWDIRLGKSPALSFKAHNADVNVISWNRLASCMLASGSDDGTFSIRDLRLIKGGDAVVAHFEYHKHPITSIEWSAHEASTLAVTSGDNQLTIWDLSLEKDEEEEAEFNAQTKELVNTPQDLPPQLLFVHQGQKDLKELHWHNQIPGMIISTAGDGFNILMPYNIQNTLPSELPA
What is the function of this protein?
Probable substrate receptor of CRL4 E3 ligase complexes acting as negative regulators of thermotolerance by disturbing the action of HSP90-1 and by preventing the expression of heat-inducible genes (e. g.  HSP14. 7, HSP21, At2g03020 and WRKY28).
What are the official names of this protein?
Protein HEAT STRESS TOLERANT DWD 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
Protein: HAT_MYCTO
Sequence: MSFGFPTFSQNRFTEQYSGLCPIAPGRGAGLQPCRRDCPVARWLVADHPVFGSDCRCRMMVGVNRVRIGRHELTGA
What is the function of this protein?
Histone acetyltransferase, which by binding to the host chromatin, may manipulate the expression of host genes involved in anti-inflammatory responses to evade clearance and to survive in the intracellular milieu.  Acetylates histone H3 at the 'Lys-9' and 'Lys-14' positions.
What are the official names of this protein?
Histone acetyltransferase, HAT.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Note=Colocalizes with the chromatin in the nucleus of infected human macrophages.
Protein: CHM4C_MOUSE
Sequence: MSKLGKFFKGTRSSRARAAPSAQEALARLRETEEMLAKKQEYLENRIQRELALAKKHGSQNKRAALQALKRKKRFEKQLTQVDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKAVHDNMDLNKIDDLMQDITEQQDIAQEISEAFSQRVQFADGFDEAELLAELEELEQEELNKKMTSLELPNVPSSSLPAQPSRKASMPSSVHRSRAASSRRAEEDDDFKQLAAWAT
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.  ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.  Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: upon phosphorylation by AURKB, together with ZFYVE19/ANCHR, retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis.  Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ANCHR and VPS4 and subsequent abscission.  ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.  CHMP4A/B/C are required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 4c, Chromatin-modifying protein 4c, CHMP4c.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein. Midbody, Midbody ring. Note=Localizes to the midbody during late cytokinesis. During its recruitment, localizes initially to the midbody arms, before being directed to the central region, the midbody ring, also called Flemming body. Phosphorylation at Ser-210 by AURKB triggers localization to midbody ring.
Protein: DFRA_VITVI
Sequence: MGSQSETVCVTGASGFIGSWLVMRLLERRLTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKADLADEGSFDEAIKGCTGVFHVATPMDFESKDPENEVIKPTIEGMLGIMKSCAAAKTVRRLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKTLAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQGQFVHLDDLCNAHIYLFENPKAEGRYICSSHDCIILDLAKMLREKYPEYNIPTEFKGVDENLKSVCFSSKKLTDLGFEFKYSLEDMFTGAVDTCRAKGLLRPSHEKPVDGKT
What is the function of this protein?
Bifunctional enzyme involved in flavonoid metabolism.
What are the official names of this protein?
Dihydroflavonol 4-reductase, DFR, Dihydrokaempferol 4-reductase, Flavanone 4-reductase, FNR.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: IF1_COREF
Sequence: MAKEGAIEVEGRVVEPLPNAMFRVELDNGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLTRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_SALPA
Sequence: MIALIQRVTRASVTVEDEVTGEIGPGLLVLLGVEKEDDEQKANRLCERVLGYRIFSDADGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSGGAAPDRAQALYEYFVERCRQQAINTQTGRFAADMQVELVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_ACTPJ
Sequence: MSTNFIYPNAHLIAGVDEVGRGPLVGAVVTAAVILDPNNPIEGLADSKKLSEKKRLLLAEEIKAKALCWSLGRAEPEEIDRLNILHATMLAMQRAVAGLNIQPDFVLVDGNRIPTLPMPAQAVIKGDSLVAEISAASILAKVARDQEMAELDVQYPEYGFAKHKGYPTKLHFEKLEQFGATPFHRKSFAPVKKILGL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_HAEIE
Sequence: MATNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTQDGAETDLDLGHYERFIRTKMTKRNNFTTGKIYSEVLRKERRGDYLGATIQVIPHITNEIKDRVIAGAQGHDVVIVEVGGTVGDIESLPFLEALRQLAVQVGREHTLFMHLTLVPYIPTAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRMIPPNERAKIALFCNVAERAVISLKDVNSIYQIPALLKSQGLDDFVCERFRLTCPEADLTEWEQVLYKQANPVGEVTIGMVGKYTELPDAYKSVNEALKHAGLTNRLSVSIKYIDSQDVETKGVEVLKGVDGILVPGGFGYRGVEGKIRTAQYARENKIPYLGICLGMQIALIEYARNVAGLTKANSSEFDKDCEQPVVALITEWQDAEGNTEVRTDESDLGGTMRLGAQQCHLVSGSRARELYGKETIEERHRHRYEVNNTLLPQIEKAGLKVTGLSADKKLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAYENHKKSVK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DUS1_SCHPO
Sequence: MASKKLHGRDFYNKIGRPKRILAPMVDQSELPWRILARRSGADLCYSPMFHSRLFGESEDYRNKVFSTRTIPEERPLIIQFCGNDPEIMLKAAKIAAPYCDAVDVNLGCPQGIAKKGKYGSFLQENWNLIESIITKLHTELSIPVTAKIRIFPDPQKTLDYAKMILKAGASILAVHGRLREQKGHFTGIADWEQIQMLRKNLPSETVLFANGNILHAQDIDRCIKYTGVDGVLSAEGSLYNPRIFLPPSSPLMTLYPRIDDMCEEYLNIIREFKLESDYSSLSAIKGHLFKLMRPLLSIHTDIRSKLAQGCTPRDFETFPPVVAMLRKRLLECEEKGEINEDKDVKESVKDSMGYPVIPWWRVQPYIRPLEVPLVTKRKPVEVTADEGPVKKKVNASVA
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:34798057).  Also able to mediate dihydrouridylation of some mRNAs, thereby affecting their translation (PubMed:34798057).
What are the official names of this protein?
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase dus1, tRNA-dihydrouridine synthase 1.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: MDTD_YERPS
Sequence: MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRIGVKWVFFSAIILFTFGSLMCAQSATLNELILSRVLQGVGDAMMVPVGRLTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEFASWHWIFLINLPVGVIGALATLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGSYWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAGLMMIPMIIGSMGMKRIIVQVVNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVLFFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQLSMSIGVSTAGILLGTFAHHQVATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1622_STRP6
Sequence: MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGKQSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNLHAGGSAQMAAFQLMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAHVTALASRPKLIGGARADYNMDIIRKS
What are the official names of this protein?
UPF0340 protein M6_Spy1622.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: FLGI_XANCB
Sequence: MNLSSLPFRLLAAAVALCAIAAPASAERIKDLAQVGGVRGNALVGYGLVVGLDGSGDRTSQAPFTVQSLKNLLGELGVNVPANVNPQLKNVAAVAIHAELPPFAKPGQPIDITVSSIANAVSLRGGSLLMAPLKGADGQVYAMAQGNLVVGGFGAQGKDGSRVSVNIPSVGRIPNGATVERALPDVFAGSGEITLNLHQNDFTTVSRMVAAIDNSFGAGTARAVDGVTVSVRSPTDPSARIGLLARLENVELSPGDAPAKVVVNARTGTVVIGQLVRVMPAAIAHGSLTVTISENTNVSQPGAFSGGRTAVTPQSTIKATSEGSRMFKFEGGTTLDQIVRAVNEVGAAPGDLVAILEALKQAGALTAELEVI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: AB4F_ARATH
Sequence: MGKKKSDESAATTKVKPSGKDASKDSKKEKLSVSAMLAGMDQKDDKPKKGSSSRTKAAPKSTSYTDGIDLPPSDEEDDGESDEEERQKEARRKLKSEQRHLEISVTDKEQKKREAKERLALQAAESAKREAMKDDHDAFTVVIGSKTSVLEGDDMADANVKDITIESFSVSARGKELLKNASVRISHGKRYGLIGPNGMGKSTLLKLLAWRKIPVPKNIDVLLVEQEVVGDEKSALNAVVSANEELVKLREEAEALQKSSSGADGENVDGEDDDDTGEKLAELYDRLQILGSDAAEAQASKILAGLGFTKDMQVRATQSFSGGWRMRISLARALFVQPTLLLLDEPTNHLDLRAVLWLEEYLCRWKKTLVVVSHDRDFLNTVCTEIIHLHDQNLHFYRGNFDGFESGYEQRRKEMNKKFDVYDKQMKAAKRTGNRGQQEKVKDRAKFTAAKEASKSKSKGKTVDEEGPAPEAPRKWRDYSVVFHFPEPTELTPPLLQLIEVSFSYPNRPDFRLSNVDVGIDMGTRVAIVGPNGAGKSTLLNLLAGDLVPTEGEMRRSQKLRIGRYSQHFVDLLTMGETPVQYLLRLHPDQEGFSKQEAVRAKLGKFGLPSHNHLSPIAKLSGGQKARVVFTSISMSKPHILLLDEPTNHLDMQSIDALADALDEFTGGVVLVSHDSRLISRVCAEEEKSQIWVVEDGTVNFFPGTFEEYKEDLQREIKAEVDE
What are the official names of this protein?
ABC transporter F family member 4, ABC transporter ABCF.4, AtABCF4, GCN20-type ATP-binding cassette protein GCN4.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily.
Protein: CHEW_HELPY
Sequence: MSNQLKDLFERQKEASAGSKQEDNEEVLQFIGFIIGDEEYAIPILNILEIVKPIGYTRVPETPNYVLGVFNLRGNVFPLISLRLKFGLKAEKQNKDTRYLVVRHNDQIAGFFIDRLTEAIRIKQTDIDPVPETLSDNNNLTYGIGKQNDRLVTILRVEEILKKDF
What is the function of this protein?
Plays an essential role in chemotaxis signal transduction system in order to colonize the host stomach.
What are the official names of this protein?
Chemotaxis protein CheW.
What is the protein family that this protein belongs to?
Belongs to the CheW family.
Protein: NOC2L_BOVIN
Sequence: MAAALSRKRRLEELTVDEFLASGFDSESESEPEGAPEAETQAVRAAAREPDGPGGSPLASRRKGGASEHKDQLSRLKDKDPEFYKFLQENDQSLLNFSDSDSSEDEEEQLHSLPNMLEEASEEEEEEDGVPRGPEGKRRDSVPVTLAMVEKWKQAAKQHLTPKLFHEVVQAFRAAVATTQGDEEGAETSKFQVTDSAVFNALVTFCIRDLFGCLQKLLFGKAPKDSSRVLQPSSSPLWAKLRLDVKAYLSSVIQLVACVAEATVAAAILQHVGSSVPYYLTFPKQCRMLLKRMVVLWSTGEETLRVLAFVVLIKVCRHKKDVFLSPVLKQMYITYVRNCKFTSPSTLPLINFMQRTLTELLALDTGVAYQHAFLYIRQLAIHLRNAMTTRRKETYQSVYNWQFVHCLYLWCRALSTICPSEALQPLIYPLSQVVIGCIKLVPTARFYPLRMHCVRALTLLSESTGTFIPVLPFILEIFQQVDFNRRPGRISSRPINFAVILKLSKVNLQEKAYRDGLVEQLYDLTLEYLHSQAHSIAFPELVLPAVLQLKSFLRECKVANYCRQVRQLLEKVQENAEHIRSVRQKVSFGVSDQRAVDAWEKRTREEGTPLTKYYSQWRKLRDREIQLEISGKERLEDLNFPEVKRRKVGDRKDEDRAEFKDLFDLESDDEDDAPDFTKRGMPGSPGAWQKVEEEDDDSSSSSGEEEVSKSEDGSPDTEAGLDPQELWQLAQGPEDELQDLQLSEED
What is the function of this protein?
Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner.  Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter.  Involved in the regulation of p53/TP53-dependent apoptosis (By similarity).
What are the official names of this protein?
Nucleolar complex protein 2 homolog, Protein NOC2 homolog, NOC2-like protein, Novel INHAT repressor.
What is the protein family that this protein belongs to?
Belongs to the NOC2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis (By similarity).
Protein: SPOP_CAEEL
Sequence: MILLAKFRNLYSKSRANDTISEGDKPEKATGDLEAGRNRLVSMEVGMGNDEVVSSGSGNSAHGRSISPSPSSASHGDPLLPVAENWCHTQVKVVKFNYMWTINNFSFCREEMGEVLKSSTFSAGCNDKLKWCLRINPKGLDEESRDYLSLYLLLVQCNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPGDRLSIFCEVSVVAETVNVTGQTNVSQLFKVPPCRLADDMYGLFDNKQFSDFTLVCKSDLGSPTQTFHIHKAILAARSRVFSAMFEHHMQESDTNMTTVDDIEPEVMRELLVYMYTGQTKYIEQMAQSLIAAADKYQLDRLKVMCEQALCYQLTTDNASLTLMLADMYSASQLRAHSINFINVNANEVMDTEGWEDLVRDHPKLLEEVFRALATQQTPPVVLVQPPKKRPKHNCPY
What is the function of this protein?
Mediates ubiquitination and proteasomal degradation of target proteins, most likely in complex with cul-3 (PubMed:16740475).  May promote the degradation of bromodomain-containing proteins such as bet-1 (PubMed:34593637).
What are the official names of this protein?
Speckle-type POZ protein homolog, BTB and MATH domain-containing protein 43, HIB homolog.
What is the protein family that this protein belongs to?
Belongs to the Tdpoz family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: PANB_LEPBJ
Sequence: MKNIHKIFSPEKKGKEKISVVTCYDFSFARILGETPIDSILVGDSLGMVFQGNSSTLPVTLEEMIYHTKVVRRGAPDKFIIADLPFLSYQTSIEEGIRSAGRMMKETDCDAVKIEGGSDFICELVAILKQIGIPVMGHLGLTPQSVHVFGGHRVQGKGEESSAKLLREAVALSESGAFSIVLEMIPAELGKRVSEEVGVLTIGIGAGPDCDGQVLVLNDLLGLDANFQPKFLKKFSNLHSIVKDAIESYHEEVRSGEFPGKDHSF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_FRAP2
Sequence: MKNYLLQIEYFGKNYCGWQRQSHSPSIQEELEKALSKIANQNIEVTCAGRTDTGVHATSQVVNFHSDADRNLSSWMRGTNALLPQGIKILDIKEVDNDFNSRFTATNRTYNYIIYNSAISSPILAEHCLWENRQLNIDKMNQACKYLLGEQDFTSFRSSQCQSNTPFRNIQKAEFIKQGSFIVFEVVGNAFLHHMIRNFIGSLLKIGLEFESPEWIKLVLEAKDRTKAAETAKAHGLYFVGVEYPEFSFRRRVIELFC
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CDK5_GLOMM
Sequence: MQKYEKLEKIGEGTYGTVFKGRNRETLEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLYDVLHSEKKLTLVFEHCDQDLKKYFDSLNGDIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCIFAELADAGRPLFPGSDVLDQLMKIFRVLGTPTEESWPGVTHLSDYVALPHFPAITSWSQIVPRLSSKGRDLLQKLLVCRPNQRVSAEQAMQHPYFTDSSNH
What is the function of this protein?
Probably involved in the control of the cell cycle.  Interacts with D1 and D3-type G1 cyclins.  Possible regulator of neuronal differentiation and/or development (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 5 homolog, Cell division protein kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.