PharMolix/UniProtQA huggingface dataset:
Protein: PG027_VACCA
Sequence: MGIQHEFDIIINGDIALRNLQLHKGDNYGCKLKIISNDYKKLKFRFIIRPDWSEIDEVKGLTVFANNYAVKVNKVDDTFYYVIYEAVIHLYNKKTEILIYSDDENELFKHYYPYISLNMISKKYKVKEENYSSPYIEHPLIPYRDYESMD
What is the function of this protein?
Inhibits antiviral activity induced by type I interferons.  Does not block signal transduction of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN (By similarity).
What are the official names of this protein?
Interferon antagonist OPG027, Host range protein 2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG027 family.
Protein: GATA1_BOVIN
Sequence: MPLGLKPTCSVCKTTSSSMWKKGPQGEILCHHCTGRGGAGGGGSCPGAAGGTGGGGGGTGGGFGAATFASTSAAPPQSNGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITAESIFYKGVYYQIGDVVSVIDEQDGKPYYAQIRGFVQDQYCEKSAALTWLIPTLASPRDQFDPASYIVGPEEDLPRKMEYLEFVCHAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAITIKETVANHL
What are the official names of this protein?
GATA zinc finger domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENO_ENT38
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRYMGKGVLKAVGAVNGPIAQAVLGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLATAKAAAASKGQALFEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKSLKEAVRMGSEVFHNLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGTDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEDLTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIDKGIVNSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: DBP10_AJECN
Sequence: MPHRDVSPAASENEFDISNLLFKGQDDLSDLERPSKKRKPQETLILDVMGDGDDGADGDEEFIAAQQTAANRKASNLRGRTVKKGGGFQSLGLNAALLKAITRKGFSVPTPIQRKTIPLVLDDQDVVGMARTGSGKTAAFVIPMIEKLKSHSAKFGSRALILSPSRELALQTLKVVKELGRGTDLKSVLLVGGDSLEEQFEYMASNPDIIIATPGRFLHLKVEMSLDLSSIRYVVFDEADRLFEMGFATQLTEILHGLPSSRQTLLFSATLPKSLVEFARAGLQEPILIRLDAESKISPDLQNAFFTVKSSEKEGALLHVLHEVIKIPTGETEALKRAKEEVKHSKKRKRSEVTSNSHKESPTEHSTIIFTATKHHVDYLTSILRTSGFAVSYAYGSLDQTARKIEVQNFRDGITHILVVTDVAARGIDIPILSNVINYDFPSQPKIFVHRVGRTARAGKTGWSYSLIRESDTPYLLDLQLFLGRPLILGRGSGQQLNYAENVVVGSLPRDKVARYTEWMTKLLDEDVDIELQREVAIKGEKLYMRTRNSASGESAKRAKAVVESAEWMMVHPLFNDESSRLEEQREKMLARVGGYKPQETIFEISGRRGANHHPPDDSDDANELRDFDGENDNAIAADNMSLASDSELEVTFSYPQSGKSNSKKDTNHPNLRESFHNPEYFMSYTPASNSLAEDRAYGVHSGSNTNFVESSRIATMDLAGDESTSRGFGEPRSIMRWDKRQKKYVSRRNDEDGSKGGKSDLLVRGESGVKIAASFRSGRFDAWKKGKRIGRMPRVGEAEAPGLGSGMPGGKKYRHRKEQAPKTPDKFRGDYEKKKKKLEAAKQRETEKAFDPSSGAKKAAVTSRGKSELKTVEDIRKARKVKELRKQKNARPSKKGKGR
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y2292_KLEP7
Sequence: MFAGLPSLSHEQQQKAVERIHELMAQGISSGQAIALVAEELRATHTGEQIVARFEDEDEDE
What are the official names of this protein?
UPF0181 protein KPN78578_22920.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: RSXD_ECOK1
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTLVQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGTVFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQVIFSGHTTSGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEEIMQYPIYSGILAGAGWQWVNLAWLAGGVWLLWQKAIRWHVPLSFLVTLALCATLGWLFSPDTLAAPQIHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWMIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFA_FRAT1
Sequence: MQIVEQMKDKALAELNLVKDKKTLDDIRVKYLGKKGELTEMMKLIATLPNDEKPKLGQAVNIAKQALQEAINLKLANFEEQELNEKLAQEKIDITLSGVGQNQGSLHPVTKTLNRIEAFFKQNGFAIEFGPEIESDYYNFETLNIPSHHPARAMHDTFYIDETHVLRTHTSGVQIRTMEKQQPPIRIIAPGRVYRCDSDITHTPMFHQVEGLLVDKDVSFADLKGLLHAFLNSFFEKDLKVRFRPSYFPFTEPSAEADIECVMCDGKGCRVCKHTGWLEVLGCGMVHPKVLKAGNIDSEKYQGFAFGMGVERLSMLRYGIDDLRMFFENDLRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_DICTD
Sequence: MPKKVVGKVKLQLPAGKATPAPPVGPALGQYGVNIMEFCKAYNAATAGQEGMIIPVEITIYEDRSFTFVTKTPPASDLLKKAAGVEKGSGEPNKVKVGKVKRSKIREIAELKMKDLNANDIEAAMRMIEGTARSMGIEIIEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RBL_BRASC
Sequence: SVGFKAGVKDYRLTYYTPDYETLATDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTSEEMMKRAACARELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOC_SYNWW
Sequence: MIIFWKGENDLSENFDRIRISLASPEQIRSWSSGEVKKPETINYRTLRPEKEGLFCEKIFGPVKDWECHCGKYKRVRHKGIVCDRCGVEVTTSKVRRERMGHIELAAPVCHIWYLKGIPSRMGLLLDMSPKVLEKVIYFVSYIVLDPGDTPLLKKQLLNEREYRENRDRYGEAFKAGIGAEAVKSLLYEVELDKMSSDLKEEIATTTGQRKSRAIKRLEVVESFRLSGNDPMWMILDVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALVDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKMHQCGLPKEMALELFKPFVMKKLVDKAIASNIKSAKKMVERGREEVWDILDDVIKEHPVLLNRAPTLHRLGIQAFEPVLVEGRALQLHPLVCTAYNADFDGDQMAVHVPLSAEAQTEARLLMLASNNILNPKDGKPVVTPTQDMVIGLYYLTFISAEAFSKENPRAFSSTDEARMAFELGQIDLHEKIRVKMSVPQKTGREILKSHEAQTFLEEIVDTSVGRIIFNDAIPTSLGFYNEIIDKKKLGNIVYECYRLEGNARTADMLDSLKSLGYEFSTRAGITVGVTDFETPLAKYDILQEADQEVEAIERDYEVGLITDEERHAQVVEIWNQATDDVTEVLKNSLSEDNPVYMMATSGARGNFQQIRQLAGMRGLMADPSGKIIDLPIKANFREGLTVLEYFISTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREDDCESVEGIWVGRIMEGSQLIEPLHQRIIGRVSVDTVIHPDTGEILVEENQMIDDDIGYEIERAGIEKVKIRSVLTCKTRHGVCKKCYGRNLATGYNVEIGEAVGILAAQSIGEPGTQLTMRTFHTGGVAGDDITRGLPRVEELFEVRKPKGQAVVVEVNGKVRFGENKGRREVEVLGENGEVLGTYPVHYGSRLKFEEGTEVEIGDALTEGPLNPHDILKTKGLQEVQRYLLQEVQKVYRSQGVDISDKHIEIMIRQMLKKVKIEDPGDTSLLPGAFVDISSFEDENNREIRAGGLPATCSPMLLGITKASLNTDSFLSAASFQETTKVLTEAAIKGKIDHLIGLKENVIIGKLIPAGTGYSAYRETSISEAPESENMVSD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MCP_HHV11
Sequence: MAAPNRDPPGYRYAAAMVPTGSLLSTIEVASHRRLFDFFSRVRSDANSLYDVEFDALLGSYCNTLSLVRFLELGLSVACVCTKFPELAYMNEGRVQFEVHQPLIARDGPHPIEQPTHNYMTKIIDRRALNAAFSLATEAIALLTGEALDGTGIGAHRQLRAIQQLARNVQAVLGAFERGTADQMLHVLLEKAPPLALLLPMQRYLDNGRLATRVARATLVAELKRSFCETSFFLGKAGHRREAVEAWLVDLTTATQPSVAVPRLTHADTRGRPVDGVLVTTAPIKQRLLQSFLKVEDTEADVPVTYGEMVLNGANLVTALVMGKAVRSLDDVGRHLLEMQEEQLDLNRQTLDELESAPQTTRVRADLVSIGEKLVFLEALEKRIYAATNVPYPLVGAMDLTFVLPLGLFNPVMERFAAHAGDLVPAPGHPDPRAFPPRQLFFWGKDRQVLRLSLEHAIGTVCHPSLMNVDAAVGGLNRDPVEAANPYGAYVAAPAGPAADMQQLFLNAWGQRLAHGRVRWVAEGQMTPEQFMQPDNANLALELHPAFDFFVGVADVELPGGDVPPAGPGEIQATWRVVNGNLPLALCPAAFRDARGLELGVGRHAMAPATIAAVRGAFDDRNYPAVFYLLQAAIHGSEHVFCALARLVVQCITSYWNNTRCAAFVNDYSLVSYVVTYLGGDLPEECMAVYRDLVAHVEALAQLVDDFTLTGPELGGQAQAELNHLMRDPALLPPLVWDCDALMRRAALDRHRDCRVSAGGHDPVYAAACNVATADFNRNDGQLLHNTQARAADAADDRPHRGADWTVHHKIYYYVMVPAFSRGRCCTAGVRFDRVYATLQNMVVPEIAPGEECPSDPVTDPAHPLHPANLVANTVNAMFHNGRVVVDGPAMLTLQVLAHNMAERTTALLCSAAPDAGANTASTTNMRIFDGALHAGILLMAPQHLDHTIQNGDYFYPLPVHALFAGADHVANAPNFPPALRDLSRQVPLVPPALGANYFSSIRQPVVQHVRESAAGENALTYALMAGYFKISPVALHHQLKTGLHPGFGFTVVRQDRFVTENVLFSERASEAYFLGQLQVARHETGGGVNFTLTQPRANVDLGVGYTAVVATATVRNPVTDMGNLPQNFYLGRGAPPLLDNAAAVYLRNAVVAGNRLGPAQPVPVFGCAQVPRRAGMDHGQDAVCEFIATPVSTDVNYFRRPCNPRGRAAGGVYAGDKEGDVTALMYDHGQSDPSRAFAATANPWASQRFSYGDLLYNGAYHLNGASPVLSPCFKFFTSADIAAKHRCLERLIVETGSAVSTATAASDVQFKRPPGCRELVEDPCGLFQEAYPLTCASDPALLRSARNGEAHARETHFAQYLVYDASPLKGLAL
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a T=16 symmetry, about 200 nm in diameter, and consisting of 150 hexons and 12 pentons (total of 162 capsomers).  Hexons form the edges and faces of the capsid and are each composed of six MCP molecules.  In contrast, one penton is found at each of the 12 vertices.  Eleven of the pentons are MCP pentamers, while the last vertex is occupied by the portal complex.  The capsid is surrounded by a layer of proteinaceous material designated the tegument which, in turn, is enclosed in an envelope of host cell-derived lipids containing virus-encoded glycoproteins.
What are the official names of this protein?
Major capsid protein, MCP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GFI1B_CHICK
Sequence: MPRSFLVKSKKAHTYHQHRFVEDDLPIFTWDPITSAFTAAGDRDKTPEDGKKQDLEWVVPKQEKDSFQPKEESVPVQYLSRMLPGPSAQDMSISGLQVKDCTNPTSMPTFYKTGFSWDAFQLPYSYRQMSSTMQSALLEHPVSLYGSHLLPSAEPPLDYSMRYSSDMETYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACEVCGKTFGHAVSLEQHTNIHSQERSFECKMCGKTFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCAKGFQRKVDLRRHRETQHSLK
What is the function of this protein?
Essential transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages.  Alters histone methylation by recruiting histone methyltransferase to target genes promoters.  Plays a role in heterochromatin formation.
What are the official names of this protein?
Zinc finger protein Gfi-1b, Growth factor-independent protein 1B.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQGB_SHIBS
Sequence: MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII
What are the official names of this protein?
Uncharacterized protein YqgB.
What is the protein family that this protein belongs to?
Belongs to the YqgB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SASA_PROMA
Sequence: MNKATANERKKLRLLLVASRKHLSRGDLRSLIRFLESEDCGFEIKLQFSDPKEQPELLELHRLVAIPALIKLDPQPKQIFAGTSILEQLKNWLPRWEQEDILISSGLGINLRQKESENGRTRNELLLEDENLVLRQENETLSNQIESQERLLRMVAHELRTPLSAAKLALQSQALGQIDLIKLQEVVKRRLEEIESLSKDLLEVGTTRWEALFNPQEANLANIAAEVILELEKFWLSRGIGINTDIPADLPNVFADQSRMKQVLLNLIENALKFSNDGDTVEITMLHRTNQWVQISVSDKGPGIPEEEQQRIFLDRVRLPQTSNETSGFGIGLSVCRRIVEVHGGKIWVVSQPGEGSCFYFTVPVWDKRNKSLEPLTLTQG
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.
Protein: PCKA_PROMH
Sequence: MNVKGLTPKDLEQYGIHDISEVIYNPSYDLLFEEETKPGLTGYEKGTLTSLGAIAVDTGIFTGRSPKDKYIVRDDVTRDTVWWADQGKGKNDNKPLSPQVWADLKSLVTEQLSGKRLFVVDAFCGANADTRLKVRFITEVAWQAHFVKNMFIRPTQEELENFTPDFIVMNGAKCTNPNWKAQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMFSMMNYFLPLKGIASMHCSANVGESGDVAIFFGLSGTGKTTLSTDPKRKLIGDDEHGWDDDGVFNFEGGCYAKTIHLSKEAEPDIYGAIKRDALLENVVVLADGSVDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHAKKVIFLTADAFGVLPPVARLTPEQTQYHFLSGFTAKLAGTERGVTEPTPTFSACFGAAFLSLHPTQYAQVLVKRMQACGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGDIDKAETQTLPVFNLAIPTALPGVNSEILDPRDTYADKAQWDVKADDLADRFVKNFDKYTDTPVGQALTKVGPKR
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_ECOHS
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHKAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RS3_SYNE7
Sequence: MGQKINPVGFRLGVTQEHRSRWFADPNRYPQLLQEDKKIRDYVRKNLSNAGIADIRVERKADQVELEIRTARPGVVVGRGGAGIDTLREGLQALLKDSSRQIRINVIEVERVDADAALLGEYIAQQLERRVAFRRCVRQAIQRAQRAGVQGIKIQVAGRLNGAEIARTEWTREGRVPLHTLRADIDYAYTTATTTYGILGIKVWVFRGEIIPGQEDAAPSNVGQPRRRNQQRRRQQFEDRSNEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: KGUA_MYCTO
Sequence: MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNLHFSVSATTRAPRPGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDLQARLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESACAELVSLLVGTAPGSP
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_MYCSK
Sequence: MAADRGLAVRVIPCLDVDAGRVVKGVNFENLRDAGDPVELAAVYDAEGADELTFLDVTASSSGRSTMLDVVRRTAEQVFIPLTVGGGVRAVADVDALLRAGADKVSVNTAAIARPELLAELARQFGSQCIVLSVDARTVPQGEQPTPSGWEVTTHGGRRGTGIDAVEWATRGAELGVGEILLNSMDFDGTKAGFDLPMLRAVRGAVTVPVIASGGAGAVEHFAPAVHAGADAVLAASVFHFKELTIGQVKAAMAAEGITVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GINM1_MOUSE
Sequence: MEGGLSAPLSVRLLLFIALPAAGWLTTNAPRPPSTAPQNGIQINVTTLSKSGEESEEQVVLNITYERGQVYVNDLPVNSGVTRISCQTLIVKSENLEKLEEKHYFGIVTVRILVLERPVTYSASSQLIVIQGEVVEIDGRQAQQKNVTEIDILVKNQRVLRYSSYFLPLEESMLYSISQDSDILFTLPDFSKKGTVSSLQTTSHYLMGNVETTVDGNALPGKLPETPLRAEPPSSYKVMCQWMEKLRKALCRFWSSVVPVLFMFLDVMVVGVLGAAGVIAVLKLLFPVCENKGILQVDKMNGISVPIILYPDGSEKTAQKLTDKTDI
What are the official names of this protein?
Glycoprotein integral membrane protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y205_ENCCU
Sequence: MRWKYAAWILIAVVDVMCCSSEEKSASVSFVTRPGSQVIAFPFIFVGHSIVVLPTTKYSNLKRNAKSMEDLTFLLSNLSHVVWSLTIDATVYKDGGRLEKLFDKRMRGYLDGVSLDVLRMYVNGSKTFSELLQIVYERTFECDSRRSRQMARYGESLIREIDNMIESMPAEMSEEEKEKMRSDLNNNRKYVESFHDTEKWRQVVEAEKMVCNTCKEICLGLKEEELMGLLAEGSAKKYIKASAGESKVSSTVYPEYIVVDISLLLDAHREHGGDVTKELVKQMLLGKKEEEIDKRYIGKVANAVKERRRRGEKEIEKRVKKLLRDEEKAKSKKRGKRKSVGVSEAKEEEKKESETEEVEAGEEVEMPSEEVGGARRKTGKKSEGGRKRYKIHRRVLRWRKSPEKIKEEWDKGSEERWRGKSLEEIREQKVFHDIMGVLELLRSPDADRFFMDTGDYTKGGSERQRMVAIGVLESGGKRMLGVVEVGTFKDCPSGCPVVYHLMFRVTGIEGMGDVMRRGGGQSW
What are the official names of this protein?
UPF0329 protein ECU02_0050.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: GATM_MACFA
Sequence: MLRVRCLRGGSRGAEAVHYIGSRLGRTLTGWVQRTFQSTQAATASSRNSFAADDKATEPLPKDCPVSSYNEWDPLEEVIVGRAENARVPPFTIEVKANTYEKYWPFYQKHGGHYFPKDHLKKAVTEIEEMCNILKMEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDRDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGKDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGTVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPTQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD
What is the function of this protein?
Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.  Creatine plays a vital role in energy metabolism in muscle tissues.  May play a role in embryonic and central nervous system development (By similarity).
What are the official names of this protein?
Glycine amidinotransferase, mitochondrial, L-arginine:glycine amidinotransferase, Transamidinase.
What is the protein family that this protein belongs to?
Belongs to the amidinotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: RS4_GEOUR
Sequence: MARYTGPSCRLCRRENTELFLKGERCYTDKCAIKRRNYPPGQHGQGRTKTSDYGVQLREKQKVRRIYGILENQFRGYFERADRLKGVTGENLLFLLERRLDNIAYRLGFASSRIEARQLVRHGHFTLNGRKVTIPSIQVKAGDVLELREKSRKVACINESLEAVVRRGIPQWLELDKGAYKGAVKTLPAREDITMPIQEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: Y5208_BACAA
Sequence: MIKPLIEFCVGNLASGSQAALEKLEKDPNLDVMEYGCLGYCGICFEGPFALVNGEVVQGATVEELVNNVYEYLDENPMF
What are the official names of this protein?
UPF0349 protein BAA_5208.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: PFD6_CAEEL
Sequence: MADMAKFEEEVNKLRTLEKDREKYFTSRQEMEMRLTESKNVKAELDLMESDSKVYKLIGAVLVRQDLEEARSTVEKRLEFIDSETKRVEASISDISKKCTEQRDKVMNMQKSFQMMAQAAAQAQKK
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).  Required for positioning of the mitotic spindle.
What are the official names of this protein?
Probable prefoldin subunit 6.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: IMCH_GEOSL
Sequence: MTLRKTAGYLWNPISLIGFLLAVVATGLIIAFIAMEMITGIDHPYIGLLVYFAFPGMLILGLILVPIGAWRVRNQRRTEVPEEVPPYPRVDFNDPHKRRLFIFFVLASVIFVLIVSVASILGFEFTESTTFCGELCHVVMEPEHKAWQGSPHARVKCVECHVGPGAEWYVKAKLSGLRQVWAVLTHSYHFPIATPIENLRPARDTCEQCHWPEKFYSGRQRVFYHYAPNKENTPREINMLIKIGGTPKSPHAMGIHWHIGTEVTYIARDRKRLDIPYVAVKQKDGSIVEYMDTEKPLTREEIAKAEKRRMDCIDCHNRPTHIYRSPAREMDEHIVSGQIDAGLPYIKKVAVEILEQPYKSKEEAHAAIEAKLPEYYAKNFPEVAKVKAAAINQAVAHVKDIYSRNFFPRMKVTWSTYPNHIGHFYTPGCFRCHDGKHKTSTGKIISKDCNMCHEMIGQKGENIPEGKVVKEFVHPADIGDALYNVNCSDCHMAAAEDSAGGEGPGKH
What is the function of this protein?
Redox protein involved in a high-potential metal respiratory pathway.  Is required only for electron transfer to terminal extracellular electron acceptors with redox potentials higher than -0. 1 V.  ImcH likely transfers electrons from the quinone pool to a periplasmic acceptor.
What are the official names of this protein?
Cytochrome c-type protein ImcH, Inner membrane cytochrome H, Multiheme c-type cytochrome.
What is the protein family that this protein belongs to?
Belongs to the NapC/NirT/NrfH family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATS1_RAT
Sequence: MQPEVPLGSGKLKPCSDMGDIQRAAKFRSSQSAHMLLLLLASITMLLCVRGAHGRPTEEDEELVLPSLERARGHDSTTLLRLDAFGQQLHLKLQPDSGFLAPGFTLQTVGRSPGSEAQHLDPTGDLAHCFYSGTVNGDPSSAAALSLCEGVRGAFYLQGEEFFIQPAPAVATERLVPAEPKEESIAPPRFHILRRRRRGSGGAKCGVMDEETLPTSNSGRESQNTPDQWPLRNPTPQGAGKPTGPGSIRKKRFVSSPRYVETMLVADQSMADFHGSGLKHYLLTLFSVAARFYKHPSIRNSISLVVVKILVIYEEQKGPEVTSNAALTLRNFCSWQKQHNSPSDRDPEHYDTAILFTRQDLCGSHTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKHCASFNGVSGDSHLMASMLSSLDHSQPWSPCSAYMVTSFLDNGHGECLMDKPQNPIKLPSDLPGTLYDANRQCQFTFGEESTHCPDAASTCSTLWCTGTSGGLLVCQTKHFPWADGTSCGEGKWCVSGKCVNKTDMKHFATPVHGSWGPWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNIEDCPDNNGKTFREEQCEAHNEFSKASFGNEPTVEWTPKYAGVSPKDRCKLTCEAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTCKKISGTVTSTRPGYHDIVTIPAGATNIEVKHRNPRGSRNNGSFLAIRAADGTYILNGNFTLSTLEQDLTYKGTVLRYSGSSAALERIRSFSPLKEPLTIQVLMVGHALRPKIKYTYFMKKKTEPFNAIPTFSEWVIEEWGECSKTCGSGWQRRVVECRDINGHPASECAKEVKPASTRPCADLPCPRWQVGDWSPCSKTCGKGYKKRTLKCLSHDGGVLSNESCDPLKKPKHYIDFCILTQCS
What is the function of this protein?
Cleaves aggrecan, a cartilage proteoglycan, at the '1683-Glu-|-Leu-1684' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover.  Has angiogenic inhibitor activity (By similarity).  Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia.  May play a critical role in follicular rupture (By similarity).
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAM-TS 1, ADAM-TS1, ADAMTS-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.