PharMolix/UniProtQA huggingface dataset:
Protein: AMIE_PSEA8
Sequence: MRHGDISSSNDTVGVAVVNYKMPRLHTAAEVLDNARKIADMIVGMKQGLPGMDLVVFPEYSLQGIMYDPAEMMETAVAIPGEETEIFSRACRKANVWGVFSLTGERHEEHPRKAPYNTLVLIDNNGEIVQKYRKIIPWCPIEGWYPGGQTYVSEGPKGMKISLIICDDGNYPEIWRDCAMKGAELIVRCQGYMYPAKDQQVMMAKAMAWANNCYVAVANAAGFDGVYSYFGHSAIIGFDGRTLGECGEEEMGIQYAQLSLSQIRDARANDQSQNHLFKILHRGYSGLQASGDGDRGLAECPFEFYRTWVTDAEKARENVERLTRSTTGVAQCPVGRLPYEGLEKEA
What is the function of this protein?
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
What are the official names of this protein?
Aliphatic amidase, Acylamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: EFP_CORGB
Sequence: MATTADFKNGLVLKNEGKLQQIIEFQHVKPGKGPAFVRTKLKDVVTGKTIDKTWNAGVKVETATVDRRDVTYLYNDGTSFIVMDDKTFEQYELSPDAFGDAGRFLLENMRVQVSFHEGEALFGELPVSVDLRVEHTDPGLQGDRSTGGTKPATLETGAEIQVPLFIETGNVLKVDTRDGSYLSRVNN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIB_SHEHH
Sequence: MTAKNIRRAYHVIRTALHYGLDDLIPSKLTPWYFKLFRYSFFWLRNQHKDKVGGERLKLAMQELGPVYIKFGQMLSTRRDLLSDEWAEELAMLQDRVPPFDSAIARASIETELNAPIESYFNDFDDIPLASASISQVHTATLKSNGAAVVLKILRPDVEQKVHADLLLMSQAADFLETLLGTNNRLRPAEVVEDYRTTIEGELNLKLEALNAIKLRNNFIDSNALYIPYMYEELCFTRLIVMERIDGIPVSDKVALEAQGTNLKLLAERGVELFFTQVFRDNFFHADMHPGNIFVSREHPNDPLYIGLDCGIMGTLTEEDKRYLAENFLAFFNRDYRRIAQLYIESGWVSPDTDVAAFEQAVKVVCEPMFNKPLDEISFGHVLLELFRTARRFDMVVQPQLVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMAEQVGPKVMAAKVKQKLPYWAEHLPELPELIYDNLKMGRNLSKNQNNLLDRYLKHQQKAHKSNYLLITSAILVICGTILINQDATLWPSYGSIGTGIALWVLGWRSRPKNRKI
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL27_THEP1
Sequence: MAHKKSGGVAKNGRDSLPKYLGVKVGDGQIVKAGNILVRQRGTRFYPGKNVGMGRDFTLFALKDGRVKFETKNNKKYVSVYEE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PYRE_STAAC
Sequence: MAKEIAKSLLDIEAVTLSPNDLYTWSSGIKSPIYCDNRVTLGYPLVRGAIRDGLINLIKEHFPEVEVISGTATAGIPHAAFIAEKLKLPMNYVRSSNKSHGKQNQIEGAKSEGKKVVVIEDLISTGGSSVTAVEALKLAGAEVLGVVAIFTYGLKKADDTFSNIQLPFYTLSDYNELIEVAENEGKISSEDIQTLVEWRDNLA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: YO29_SCHPO
Sequence: MNKRQSQLKFGNEGISLAVPKQSLQECSYMSNLITDRESTFLSYFVPSKDPKMLPVYRFMFQESADLKHCNHKMQAWRFPNEIEAFNDDGEEYSGQKLLNVLRKEDVYGMVVCVRWYGGQLLGPVRFQHITNTAKQSIDKYKSVLEEERKKQLLRTETGLLRQSSSRSSSLLDQRIRQITAKDKTVNLLRKTLNRPLLHEVDYHGKSLEILDMLLQSRNSMISSLRSELQEKNQKDKKKEVNKLEEKMTNAKEPNVNVPSMKASSAISVETPETIESEASVDHKEASKIIKDVEKEE
What are the official names of this protein?
IMPACT family member C14C8.09c.
What is the protein family that this protein belongs to?
Belongs to the IMPACT family.
Protein: NRDR_RHIWR
Sequence: MRCPFCAHDDSQVKDSRPTDDGAAIRRRRQCEGCGARFTTFERIQLREMTVVKSDGRREVFDRSKLERSISVACRKRPVDPARIERLATAIQRQIETSGDSEIPAASVGGMVMDGLKALDSVAYIRFASVYKDFREAKDFEDFAGAVSEAGRDG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CWZF5_ORYSJ
Sequence: MGGGRRGGRREAEEGVAVAGRSRGVAAAAARHEVAGELELASAGGLGGGGGDELVDPDQLTYIHNVFKIDLYSHVLVNLLVTICKDEKLQNILGHFQKEFEGGVSAENLGSQYGGYGSFLPTYQRSPPALSQSGSPAVLPNHGSASRSPYIPLESVQKNHFVKQAIDGRRKNNYCQRTSSENDSNHSQQLLNSGPEQKTAKIRIKVNNKCLERNNAAIYSGLGLDISPSSSIDDSPQWSIEAPESKLFPDESADTIFQIMTCHSVPGGLLLSPLAENVLELRQKSTAVTKKHEAPVYDNDKEELQRNCCHTSSAAPDNNYQLVKKIKLDEQRDHLPEFENSKYRHKNATIMKKGAKPELKDISDEIDSIRAPRCAKTEKHAVGESADFIADTSGRLKEAKNGQFKGKGSTQSSLSIIDVKAANSANDDKHPKGKAKLKVTLVRNAKMESSLDDGFSHKTKSDKCNDQPVTTSSQLQIDPAKKTSLKRDRGKVVCAKDEPSQYKSKELRSLVDAESMGTTTENVAGNSSELLKGKKVSALQASLFGKKLKIKTHKKPNYDTTRKPNGENEGYVLDHRNGSTYLHTEDKSLKTEKESATSGLTDKDFSGGGNDGDHKISPIVVDKSASMPSRCKNETTEASMAVPASEPVDQWVCCDKCETWRLLPYGMNSDTLPKKWRCSMQSWLPGMNNCKLSEGETTNAIRALYVVPIPENNISLDSRCDTATLVRSNDAAIMSDNLGMPEISKSSKKLHAPRNRDGLDCFPKLKEKQKRIESSDKGEKSTVTISSGQTMAKDRMHRKRKTSGADYDNLIASKKLKKVYNEPPKHQPPQFELSKSRPSTKGSLKELPKHTNISPGMGKHALPSSGKQFCDGDNSDRGARASDAGKSDPRDLFIKKNKSKQMQLRQHGPDPRPSDAFAKHVVKEVLSESNAAKEKLGSDLKFLKVDDHEKSAHARGPVTGTNSNAIFSEKEDLIEQHLENIHFQHPLLSESSVRRNICNVQASTAATSSSSKVSSSHKNKPEFQETRTSPVESVSSSPLRTSDKKHLDRHRTNSYAVAEIVHSQESVKTGASCSKEKYGFECGSDHTKPHVSGCSNRVMHQDALEDGDLDKQNILTNGVFNNRSSGLGIRNDQGQPNSLVEQKVNSHVLPIHGSGDFRRPTPDQNGKTLPQYNSNQSDQAKLSSGKHPTQVRPDKGNVEYIDLKTNPSTVAGSKLLPGLNNKVNGNASNKSKQSVVENMKHAAIHVDASTPINASALLKEARDLKHLSDRLKGKGDDLESANICFEACLKFLHVASLKEAAGVDSSKQGDPINTMTLYSDTGNLCGFCAREFERLKKMANAALAYKCVEVAYMKAAFYKHPGAIKDSHALQAASVIAPPAESPSSSASDVDNLNNPSTIAKIVSTRGLCTSQIAKNPISRSNHHLMGLLAYSFSYDPFCLLDKVEDTNYAFEGTRKSQSAFFSYLSGIEKDQADGIALLTEVLNFSFHNVKGLLQLIRHSLECINHERFK
What is the function of this protein?
Binds to histones H3K4me1, H3K4me2 and H3K4me3 in GST pull-down assay (PubMed:28818372).  May facilitate the recruitment of effectors to mediate gene expression (By similarity).
What are the official names of this protein?
Cysteine-tryptophan domain-containing zinc finger protein 5, OsCW-ZF5.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_SYNP2
Sequence: MPRVKRGNVARKRRKKILKLAKGFRGSHSKLFRTANQQVMKALRNAYRDRRKKKRDFRRLWIVRVNAAARLNGLSYSKLTHQLKKANIEINRKMLAELAVVDPQAFAQVVEVAKSA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MALT_ECOLI
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides (PubMed:7040340, PubMed:3305511, PubMed:2538630, PubMed:2524384).  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box (5'-GGA[TG]GA-3') (PubMed:2538630, PubMed:2524384).  Displays weak ATPase activity, but this activity is not required for promoter binding (PubMed:2524384).
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: ASD2_CAEEL
Sequence: MDCDNGVVSEISDDKELLNLETVIPPPPNDSGHEFIGPSSGPPQVTITPSGVQSGSANGVSTSQQQQYSAEYLSQLLKDKKQLAAFPNVFHHLERLADEEINKVRVVLFQCEFSKESAPLPDAEGDSTVHTEKVFVPAKEHPDYNFVGRILGPRGMTAKQLEQETGCKIMVRGRGSMRDKKKEELNRGKPNWEHLSEELHVLIQCEDTENRAKVKLMRAVEEVRKLLVPAPEGEDDLKRKQLMELAIINGTYRSGTDQSALAAAQLAAVKHQQQPFAAALQAAALQRGVLPMMANGLSRSPTMAVCGAPIVMSPSGRASSAGATATSQAALIMQQQSQLHAANAGNAALQQQAALLQQQQAAEYQQLLLSQAGLYDFSAMQQQYAAVGQNAAVAAAQAQAQAQYGALAAAAAANSAGNQQYADYAGVDLTSQQSAHGGYYVRRWA
What is the function of this protein?
RNA-binding protein that binds to the 5'-NACUAAY-N(1,20)-UAAY-3' consensus sequence in pre-mRNA introns to promote alternative splicing (PubMed:18230701, PubMed:20573244, PubMed:23071450).  Required for mutually exclusive alternative splicing where it modulates the switch between mutually exclusive exons during pre-mRNA maturation (PubMed:18230701, PubMed:23071450).  Involved in muscle-specific gene expression regulating the alternative splicing of genes such as let-2 and unc-60 to ensure that their respective isoforms are expressed in muscle (PubMed:18230701, PubMed:23071450).  Promotes the removal of intron 10 from let-2 pre-mRNA to allow for the exclusive expression of the muscle-specific let-2 isoform (as opposed to the non-muscle-specific isoform expressed in embryos) in body wall muscles during late larval and adult stages of development (PubMed:18230701).  Binds cooperatively with RNA-binding protein sup-12 to intron 1A of the unc-60 pre-mRNA to promote alternative splicing and expression of the muscle specific isoform of unc-60 (PubMed:23071450).
What are the official names of this protein?
RNA-binding protein asd-2, Alternative splicing defective protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUB_SODGM
Sequence: MGRPSRRGRDIDGIVLLDKPLGLSSNDLLQKVKRLFRANKAGHTGALDPLATGMLPVCLGEATKFSQHLLDADKRYRVIARLGERTDTSDAEGQTVSVRPVSLDKTRLEAALDHFRGESSQVPSMFSALKHQGRPLYEYARKGITVEREARPIHVYDLQLHRWDLTKVELEIHCSKGTYIRTIIDDLGERLGCGAHVMALRRLAVARYPIERMVTLAALQAIAADAPPDTLAQLDALLLPMDSAVADMPLVNLPSDLAARLRLGQTVAVTAQPQAGLVRLTEGDAGRFFGIGEIAAPGRLTPRRLIAEPRA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: NSP11_RGDV
Sequence: MTSNEENPVGVQTLKPNNDAKRVFEMRKIPSSNVMRVEYTKQSKYRTCVCPSALHFAEECPSNDVLFSVGAHRNMLCVAKAFDQTKPRGMQRGNRRNNVAKVMTLNELMPKDDSNDRKKAKTSKDRKVEKSSRGRASSSRSRGRGGFSRNGRDRRETDSQDEYSEDNSYKSEEESTEDETAPLTKKDMLKMMSMFQSGAKSKRRPR
What is the function of this protein?
Constituent of viral factories.  Binds to ssRNA and dsRNA (By similarity).
What are the official names of this protein?
RNA-binding protein, Non-structural protein 12, Pns12.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus RNA-binding protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Constituent of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: INLC_LISMG
Sequence: MLKKNNWLQNAVIAMLVLIVGLCINMGSGTKVQAESIQRPTPINQVFPDPGLANAVKQNLGKQSVTDLVSQKELSGVQNFNGDNSNIQSLAGMQFFTNLKELHLSHNQISDLSPLKDLTKLEELSVNRNRLKNLNGIPSACLSRLFLDNNELRDTDSLIHLKNLEILSIRNNKLKSIVMLGFLSKLEVLDLHGNEITNTGGLTRLKKVNWIDLTGQKCVNEPVKYQPELYITNTVKDPDGRWISPYYISNGGSYVDGCVLWELPVYTDEVSYKFSEYINVGETEAIFDGTVTQPIKN
What is the function of this protein?
A virulence enhancer that has at least 2 dissociable functions in infection; it impairs translocation of host transcription factor NF-kappa-B to the nucleus and antagonizes the function of the Tuba dynamin-binding protein, promoting bacterial spreading (PubMed:20855622, PubMed:19767742, PubMed:24332715).  Perturbs the morphology of host cell junctions by impairing host DNMBP (Tuba) and WASL interaction, altering cortical tension at the cell junctions and allowing bacteria to more efficiently form bacteria-filled cell protrusions which promote bacterial spreading within infected host tissue (PubMed:19767742, PubMed:24332715).  Down-regulates the host inflammation response usually induced by Listeria infection.  Interacts with host I-kappa-B kinase alpha (IKKA, CHUK), which prevents IKKA from phosphorylating NF-kappa-B inhibitor alpha (IKBA, NFKBIA) and thus delays degradation of phospho-IKBA.  Translocation of host transcription factor p65 (a subunit of NF-kappa-B, RELA) into the nucleus is impaired, which prevents activation of NF-KB-regulated genes (PubMed:20855622).  Recognized by serum from healthy humans exposed to L. monocytogenes as well from patients who have recovered from listeriosis (PubMed:9284184).
What are the official names of this protein?
Internalin C, InlC, Internalin-related protein A.
What is the protein family that this protein belongs to?
Belongs to the internalin family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm.
Protein: NU4C_ILLOL
Sequence: MSHFPWLTIIVVLPISAGSSIGFLPYRGNKAVRWYTICICILELLLTTYAFCYHFQLDDPLIQLEEDYNWINLFDFNWRLGIDGLSMGPVLLTGFITTLATLAAWPVTRDSRLFHFLMLAMYSGQIGSFSSRDLLLFFMMWELELIPIYLLLSLWGGKKRLYSATKFILYTAGGSIFLLMGVSGMGLYSSNEPTLNFETLTNQSYPVALEIIFYIGFFIAYAAKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSIFSPWLMIIGAIQIIYAASTSPGQRNLKKRIAYSSVSHMGFITIGIGSITDTGLNGSILQIISHGFIGAALFFLAGTTYDRIRLVYLDEMGGIAILMPKMFMMFSSFSMASLALPGMSGFVAESVVFLGIITSPKYFLMPKILITFVMAIGMILTPIYSLSMSRQIFYGYKLFNVSNSYFVDSGPRELFILICILLPVIGIGIYPDFVLSLSVDKVEAILSSYFHR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TSAD_LEPIN
Sequence: MIGMGIETSCDETSIGIVRDGKDLLSLKIFSQIDLHKPYGGIVPEIASRAHLEKINLLLEEAMEESEIQFKDLSYVAVTSSPGLTGSLMVGAQMARCIHMVYETPILPVCHLQSHFAVLHLEGVPTEFPVLGLLLSGGNSAIYILHEFGKMELLGDTMDDALGEAFDKVAGLLELPYPGGPHIEVRAKEYKPSPNEKPILPALLRNLPQEEVSFSFSGLKTAVMVLLEKQKELSKERICWNFQNSAFDLVERNLKRAVSKTGIKRIFAAGGVLANFTLQNRLYTWAEKNSVELFAPKKKIYCTDNGAMVASLGYYLFQKGYQRDIDFTVSPSRQEIFS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_BORGP
Sequence: MNQSKKILRTVYLSLFLIGLFMLINDIFSSIMLSFKSSDKEVQFDLNKSFDDNEIFLSKSNGFDLINKSQNIVVETEIYFATFSTFRGNLVSLKLKNHLNLEKDPTDLINVDYKNETFFDVSLDYLVEDLFLYKKIDNLNHEFKAYFKNHGKIYEYVKKYTFSEKNEYLMKFTVIVNSLNDYDLFDIDSYKIVFSSEIERLSDKAKLQYNNYLSQIIYYDNKLKYGKDGLSINNPRWIGSSTKYFEVLISRENMEVEFKKERGVLKSFIVNNVGNKKNISDEFFIYAGPKDNRYLDIFDKSGDNTFGLSDIAFGMSVEKSLWYLIQVPMQMVMQVFYDVIPNWGLSIIFLTIVVRILIFPLTFKGFRATAELSKLQPKMKELQVKFKHDPKKLNEEMGRLYKEEGVNPLGGCFPVILQLPIFFALYSLVNNLFLLRGASFIPGWIDDLSIGDSVYNFGYRLYFVSWTDIRILPFIMMFTQLGSTIVSSNLDLKNLGAQQKFLYFGMPIMFFFILYNMPSGLLIYWITTNIFTILQQYYIKMHLS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AATP3_ARATH
Sequence: MFPSSDFSFSPSSLFSAYASLTGFLMLFRSMLHDFVPEKLRSYFSSLLDRFFTPKSKYLTVIIDENFGLNRNQVFDAAEMYLRSKIGPETERLRVGKIPKQKHFTISIERGEEILDTFEESEVKWSYVQSENEKGDKVKRYYELTFEKKLRDKVLNSYLTHVVAESEEIKRNLRVVKLYSRDVYASDDDDGMAGGNWGCINLEHPSTFDTLAMDPNAKKKIIDDLERFLKRKEFYKRVGKAWKRGYLLYGPPGTGKSSLIAAMANYLKFDVFDLELSSIYDNGELKRVLLSTTNRSILVIEDIDCNAEVRDREAENQEDEQIKGKVTLSGILNFIDGLWSSFGDERIIVFTTNHKERLDPALLRPGRMDVHINMSYCTGLGFRTLVSNYLGLDGLNHPLCEEIEALVDSTEVTPAELAEELMQDDDTDVVLRGVISFVEKRKVERSKTKKEVSICKATDDDEKQNGSLGCVKKKKKGGKQKGKGKGKGKAKTYLI
What are the official names of this protein?
AAA-ATPase At2g18193.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RPAP3_MOUSE
Sequence: MTSASKAVELQLQVKHNAEELQDFMRDLEHWEKDMKEKDLELRRQGGVAEENLPPIRNGNFRKKKKKGKAKESSRKTKEENTKNRIKSYDYDAWAKLDVDRILDELDKEDSTHDSLSQESESDEDGIRVDSQKALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLELEPDNFEATNELRKINQALTSKENSGPGAAAAAESKPAAGESKPTGGQQGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRYEEAERDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAATELSRIKKELIEKGHWDDVFLDSTQRHHVVKAVDNPPRGSPKALKKVFIEETGNLIETVDAPDSSATVPESDRATAAVGTGTKKNPSEGVSLPAGDRPRAKVLKIEAVSDTSAPQAQVGVKQDARQPGSEKASVRAEQMPGQLAAAGLPPVPANSFQLESDFRQLRSSPEMLYQYVKNIEPSLYPKLFQKNLDPDVFNQIIKILHDFYIEREKPALIFEVLERLSQLRRFDMAVMFMSGPERKLTNVLFNHLEKSDLKEDSVEELKKRYGG
What is the function of this protein?
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.
What are the official names of this protein?
RNA polymerase II-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the RPAP3 family.
Protein: SYV_NEIMB
Sequence: MLDKYNPAEIESKHYQNWEEQGYFQPDMDLTKPSFSIQLPPPNVTGTLHMGHAFNQTIMDGLTRYYRMKGCNTAWIPGTDHAGIATQIVVERQLAAQNVSRHDLGREKFLEKVWEWKEVSGGTITQQMRRVGCSADWTREYFTMDDVRAETVTEVFVRLYEQGLIYRGKRLVNWDPVLGTAVSDLEVESVEEQGSMWHIRYPLADNPAEAVIVATTRPETLLGDVAVAVNPEDERYTHLIGKELILPLTGRTIPVIADEYVEKDFGTGCVKITPAHDFNDYEVGKRHDTRLINVFNLEAKVLANAEVFNFKGEAQLGFALPEKYAGLDRFAARKQMVADLQEQGFLVEIKPHTLMTPKGDRTGSVIEPMLTSQWFVAMSATPNGGEPDSEFKGLSLADKAKKAVDSGAVRFIPENWVNTYNQWMNNIQDWCISRQLWWGHQIPAWYDNEGNVYVARNQEEAEKQAGKTGLTREEDVLDTWFSSALVPFSTLGWPSETDELKAFLPSNVLVTGYEIIFFWVARMIMMTTHFTGKVPFKDVYIHGIVRDHEGKKMSKSEGNVIDPVDLIDGIGLEKLLVKRTTGLRKPETAPKVEEATKKLFPEGIPSMGADALRFTMASYASLGRSVNFDFKRAEGYRNFCNKIWNATNFVLMNTENQDCGYGATAAEPRGYSFPDMWIVGRLNQTIEQVTQAYETYRFDLAAETLYSFVWNDYCDWYLELAKVQLQTGCASRQRATRHTLLRVLEAALRLLHPIIPFITEELWQTVAPMCDAKTADSIMLARFPEADSGEIVQTAFEQMTVLQDLIGAVRNLRGEMGIQPNVKAPLFVESTDDLADYLKYLPMMTRLTEAQQVAALPESEDAPVAVCNGARLMLKVEIDKAAETARLSKEAEKLQKALDKLNAKLSKPGYTEKAPAHLVEKDKADLAELEDKMAKVQNQLAKLKD
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMM1_TALMQ
Sequence: MSQHSQYDAPGVPVQPSLSFTQGFLLGQLSVVLLIGAFIKFFIFGEAPAPPSRGLASRTASHHRSYSINQGDNNVSNNNTSGGSPRTLCEKPSTSNVLRPVPSSATNTRSILRKTYYNAIPTQFSHTKQGRHRIQHSTHQPESLDWFNVLIAQTIAQYRQTAYLLKDSPTSSILDSLSAAINDPQKKPSFIDTIKVTDISLGEEFPIFSNCRVIVVDDPNSDGGRLQALMDVDLSDDNLSLAIETSLILNYPKPRSAVLPVALSVSVVRFSGTLCISLIPAATEQSPSSAPTPDASNLNVRTLFQHISAELNGTAANPTANPEKKGVPKTNLAFSFLPDYRLDLSVRSLIGSRSRLQDVPKVAQLVEARIHSWFEERVVEPRVQVVGLPDFWPRKGRTGVRPGEDAEAAAAVAAASASSRGGAPEATPSVPEEAIIDDSPVRPGLRFRGPAGRYDSGSSFDELPRAGPGLGEPLDIPGSMPGGRAQ
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: NU3C_PROM4
Sequence: MFSLQGYDAFLGFLLISAAVPVLALVTNKLLSPKSQTGERELTYESGMEPIGGAWIQFNIRYYMFALVFVIFDVETVFLYPWAVAFHKLGLLAFIEALIFIAILIVALAYAWRKGALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MDH1_BURVG
Sequence: MSKPARRVAVTGAAGQIAYSLLFRIARGDLLGDDQPVILQLLELPHALDALRGVVMELEDCAFPLLQSVEISDDPRVAFRDADYAMLVGSRPRGKGMERRDLLAANAAIFRSQGEALNEVANRQVKVLVVGNPANTNAWVARHYAPDLPADAITAMIRLDHNRAVSKLAARCGVTVDAVSRMAVWGNHSPTMFPDYRHALIDQQPAPMRVGDERWYLDTFIPEVARRGTAIIEARGASSAASAANAAIDQMRDWIRGSGGRWVSMSIVSGGEYGIPRGLMFGMPTICSEGRYRVVPDLEIDALARARIDASVAELVDEMQAVRAILAL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.