PharMolix/UniProtQA huggingface dataset:
Protein: CHSY_MALDO
Sequence: MMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEVEKPLFELVSAAQTVLPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEALKPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLETTGEGLEWGVLFGFGPGLTVETVVLHSVAA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase, Naregenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: APOC1_AOTNA
Sequence: MRLFLSLPVLVVALLMILEGPGPAQGAPEAVDTSSGLDKLKEFGTTLEDKVREFFNRVKESDIPAKTRNWFSETLQKVKEKLRIES
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBT_ACOCL
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LOT6_YEAST
Sequence: MKVGIIMGSVRAKRVCPEIAAYVKRTIENSEELIDQKLKIQVVDLQQIALPLYEDDDELIPAQIKSVDEYADSKTRSWSRIVNALDIIVFVTPQYNWGYPAALKNAIDRLYHEWHGKPALVVSYGGHGGSKCNDQLQEVLHGLKMNVIGGVAVKIPVGTIPLPEDIVPQLSVHNEEILQLLASCIETTRNK
What is the function of this protein?
Has several reductase activities that are NAD(P)H-dependent and involve FMN as a cofactor, ferricyanide being the best substrate for reduction.  May be involved in ferric iron assimilation.
What are the official names of this protein?
NAD(P)H-dependent FMN reductase LOT6, FMN reductase LOT6, Azoreductase LOT6, FMN reductase [NAD(P)H], Low temperature response protein 6.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GPA1_LUPLU
Sequence: MGLLCSRNRRYNDADAEENAQAAEIERRIELETKAEKHIQKLLLLGAGESGKSTIFKQIKLLFQTGFDEAELKSYLPVIHANVFQTIKLLHDGSKELAQNDVDSSKYVISDENKDIGEKLSEIGSKLDYPYLTTELAKEIETLWEDAAIQETYARGNELQVPGCAHYFMENLQRLSDANYVPTKEDVLYARVRTTGVVEIQFSPVGENKRSGEVYRLFDVGGQRNERRKWIHLFEGVSAVIFCAAISEYDQTLFEDENKNRMTETKELFEWILKQPCFEKTSFMLFLNKFDIFEKKILKVPLNVCEWFKDYQPVSTGKQEIEHAYEFVKKKFEELYFQSTAPERVDRVFKVYRTTALDQKLIKKTFKLVDESLRRRNLFEAGLL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-1 subunit, GP-alpha-1.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: RS13_METMA
Sequence: MLHALQWRKYMAEENNNEELRHLVRIMNTDLKGAKPVEYALTGLPGIGRRTAILIAKGAGVDPTATLGYLPDEEVAKLDAAIGKFEEIVPSWMLNRQKDLTTGQDKHLLGTDILLTFREDINNLKKVRAYRGLRHERGLKVRGQRTKSTGRRGSTVGVSRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: COPA_ECO57
Sequence: MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVTGTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQLLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYGAEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSLWLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQWFPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEKSVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGTVVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALVSAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDADALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADFDEAQALRLAAALEQGSSHPLARAILDKASDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNDQQVDTKAIEADISAQASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANAIAKEAGIDEVIAGVLPDGKAEAIKRLQSEGRQVAMVGDGINDAPALAQADVGIAMGGGSDVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWPFTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE
What is the function of this protein?
Probably also encodes a cytoplasmic copper chaperone CopA(Z) that is produced by programmed ribosomal frameshifting (Probable).
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase, Soluble copper chaperone CopA(Z).
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
[Copper-exporting P-type ATPase]: Cell inner membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform Soluble copper chaperone CopA(Z)]: Cytoplasm.
Protein: Y2203_SHEPW
Sequence: MGIKDWPQGEGPREKLLLDGAEQLSDAELLAVLLRVGLKGLSAVELARMMITEFGGLRSLLTASQAQVCRLDGIGPVKFAQLQAAVEIGKRISKENLKRGKILSDPDLTRDYLMRQLGDRAYEVFAILLLDSQHRVIQFVELFRGTINSASVYPRDVVGLVLEKKAAAVIVCHNHPSGIAEPSTADRRITERLKQALQTIDVSLLDHMVVGDREIVSFAERGWID
What are the official names of this protein?
UPF0758 protein swp_2203.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MENG_CHLT2
Sequence: MTDFHDKPNIQIMFDSLAPTYDKINGILSLGLHIAWNNALVSLLGETNHLLDLCAGTGRVALSYVQNYPRASATLVDFSTKMLENVQKRHPSAPFSYITSDVTHLPLPDNTFRLASMAYGLRNLSYPLEALREVYRVLQPGGHLGILELTRPATYNPVYLLHKLYLNLVVPSVGRFYSGNSYAYSYLKESIRDLPRDAALEAIFHAAHLRPIRKRKLLFGTATIWILEK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: CLPP4_ARATH
Sequence: MGTLSLSSSLKPSLVSSRLNSSSSASSSSFPKPNNLYLKPTKLISPPLRTTSPSPLRFANASIEMSQTQESAIRGAESDVMGLLLRERIVFLGSSIDDFVADAIMSQLLLLDAKDPKKDIKLFINSPGGSLSATMAIYDVVQLVRADVSTIALGIAASTASIILGAGTKGKRFAMPNTRIMIHQPLGGASGQAIDVEIQAKEVMHNKNNVTSIIAGCTSRSFEQVLKDIDRDRYMSPIEAVEYGLIDGVIDGDSIIPLEPVPDRVKPRVNYEEISKDPMKFLTPEIPDDEIY
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins (By similarity).  Essential protein required for chloroplast development and integrity (PubMed:16705403, PubMed:17241447).  Essential for Embryogenesis (PubMed:23548781).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 4, chloroplastic, Endopeptidase ClpP4, nClpP4, nClpP3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: MURI_MYCBT
Sequence: MNSPLAPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLTIPEIRAHALAIGDDLVGRGVKALVIACNSASSACLRDARERYQVPVVEVILPAVRRAVAATRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVACPRFVDFVELGVTSGRQVLGLAQGYLEPLQRAEVDTLVLGCTHYPLLSGLIQLAMGENVTLVSSAEETAKEVVRVLTEIDLLRPHDAPPATRIFEATGDPEAFTKLAARFLGPVLGGVQPVHPSRIH
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: BST15_CAEEL
Sequence: MTVNYNLDVSSASIFSFLRLQLRWKGSIWKYLLKELFMFIIAFITVSSVYRSNLIIGEKTRKIWDNFAALFDQNMDFIPLTFMLGFFVTIIVRRWNDIFANLGWVENTAITVANYIRGTDDRTRMIRRNVIRYMVLAQVLVFRDCSIQVRKRFPTMESIVSAGFMLEHEKEALDNVQCGKLQKYFVPIQWSTGLLVDARAEGKIAADLLMNEIGKHIIEFRKMLALLSNYDWVPIPLAYPQVVFLAVRSYFFMALIARQSVLLDGKEPEQPSILYPTVPFVMSILQFIFVVGWMKVAESMINPLGEDDDDFECNYLLDRNLMIGLCIVDDNYNRTPSVEKDAFWCADVEPLYSVETAMIPKNPQIGSAANYDVKVDEEEVMMMPHMDDVDLFDFESTNNLIPRKTFSVISIQRPFGSRASLASRKRSMMFDQLRGRIAKKQHRSNMFQNSVSQASLHYFESQAPSEINLSTLEMTAPKRKSSTGKLGSMNVAEEQHKLSAEVLPIVIEEDEERSKMLEKDKNKNA
What is the function of this protein?
Forms chloride channels.
What are the official names of this protein?
Bestrophin homolog 15, Bestrophin-1, ceBest1.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAD_NOSP7
Sequence: MIAIYPGSFDPITLGHLDLIQRGSRLFERVIVAVLRNPNKTPLFSVQQRLEQIRLSTQHLPNVEVDSFDGLTVNYAQMRHAQVLLRGLRAVSDFEVELQMAHTNKTLSTQIETVFLATSNEYSFLSSSVVREIARFGGSIDHLVPPHIALDIYQCYNHNSPMLNPISTEAIPPLKNISVEREA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_METM5
Sequence: MLTKRIIPCLDIKEGRVVKGTNFVELRDAGDPVELSKIYNEQGADELVFLDITASFEKRDIIIDVVKRTAEQVFIPLTVGGGIKTVDDFRKILRAGADKISINTSAVKTPELIKEASEIFGTQCVVVAMDVKRNYITDIQDENLKDKNVFETELGSCWFEVYIYGGREGTGIDAIEWAKKVENLGAGEILLTSMDADGTKDGYDLVLTKSISKNTNLPIIASGGCGNSKHVVDAFKDGKADAALMASILHYRECTVNDLKKEIEKNNISVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_FUSNN
Sequence: MAKEVIQIIKLQLPAGKANPAPPVGPALGQHGVNIMEFCKAFNAKTQDKAGWIIPVEISVYSDRSFTFILKTPPASDLLKKAAGITSGAKNSKKEVAGKITTAKLKELAETKMPDLNASSVETAMKIIAGSARSMGIKIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: Y919_LACAC
Sequence: MESWLFLALILVVALLGKNMSLIIATAVVMLFKLLPFTGKWLPTIQAKGINWGVTIISVAILIPIATGQIGFKDLIRTFKTPAGWIAILAGIAVAVLSRYGVNQLAAVPQVTVALVLGTIIGVVAFKGVAAGPVIASGMTYLVVTLFNLHF
What are the official names of this protein?
UPF0756 membrane protein LBA0919.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL6_SYNS3
Sequence: MSRIGKNPIPIPDKVNVTLSGLAVTVKGPKGELKRTLPSGVSVNQVDNSIVVAPTSTKRSSRERHGLCRTLVANMVIGVSQGYSKKLEIVGVGSRAQVKGKTLVVSAGYSHPVEVVPPEGITFTVENNTNVTVSGTDKELVGNEAAKIRAIRPPEPYKGKGIKYAGERILRKAGKSGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MTKA_RHILO
Sequence: MDIHEYQAKELLARHGVHVPRGGLAYSPEQATYRAREIGGGKWVLKAQVHSGARGKAGGIKLCANDEEISSAAEAMLGRKLVTQQTGPRGKLISRLYLEEAVDIAQELYVGFVLDRKEERVMIVASAAGGMEIEDIVEKEPNSILRTSVDPGVGMQRFQAREIAFGLGLDHNLIGKATETIFSCYQVFRDYDASMLEINPLVVTRDGNLIALDAKMSFDENALFRRPEISELRDKSQEDPRETFASDRGLSYVGLDGNIGCIINGAGLAMATMDMIKIAGGEPANFLDIGGGASPERVAKSFRAVLGDKNVETILVNIFAGINRCDWVAEGVIKAIREVGVNVPLVVRLSGTKAEEGRRILADSGEAVIVADTLAEAAEKAVAAWRAAAKKKAA
What are the official names of this protein?
Probable malate--CoA ligase subunit beta, MTK-beta, Malate thiokinase, Malyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: ADCK5_MOUSE
Sequence: MWRPMRLCHFHSTLLQSRQKPWPCPAIFFRRNFKSPPARTSRARLLWRRALSATVVGTPFLLGAYYFMAEASERRKLRLAVDGIGRFGRSVKIGLFISTDYWWCTNVVLRGVEENSPKYVEIMSACHQRAADALVAGAIRNGGLYVKLGQGLCSFNHLLPTEYIQTLRVLEDKALTRGFREVDELFLEDFQALPNELFQEFDYEPMAAASLAQVHRAKLHDGTDVAVKVQYIDLRDRFDGDVQTLELLLRLVELMHPSFGFSWVLQDLKGTLVQELDFENEGRNAERCAQELKHFHYVVIPRVHWDRSSKRVLTADFCNGCKVNDMEGIKSQGLAVQDVAKKLIQTFAEQIFHTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLDEKDRSSLCQLWRAIILRDNAAMKKHAAALGVQDYMLFSEVLMQRPVRLGQLWGSHLISREEAAYMQDMAREHFDGIMEVLKALPRPMLLVLRNINTVRAINSNLGTPVDRYFLMAKSAVWGWSRLVGAAYQGIYGSSLLRHIKVLWEALKFEMALRLEILAMRLTALMLRVLVRLGFAPKAEAEEVYQYLEM
What is the function of this protein?
The function of this protein is not yet clear.  It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
What are the official names of this protein?
Uncharacterized aarF domain-containing protein kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS9_STAAT
Sequence: MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: HIS6_ECO81
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAGKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_RUEST
Sequence: MDLIAQLEAEQIAALGKEIPDFKAGDTIRVGYKVTEGTRTRVQAYEGVCISRKNGSGIAGSFTVRKISFGEGVERVFPLYSTNIESIEVVRRGRVRRAKLYYLRSRRGKSARIAEDANYKAKA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: CP318_DROME
Sequence: MHLNIALWACGALLAVLLAWQQRKCWRLIWQLNGWRGVIQQPVLWLLLCINLHPNSILEKVSQYRVHFQRPLAVLVGTRVLLYIDDPAGMECVLNAPECLDKTFLQDGFFVRRGLLHARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWLQIRLLHRLLAPELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANGEMTLEEIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKNADDILLTIQPKKEST
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 318a1, CYPCCCXVIIIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: OTC_PSELT
Sequence: MAINLTGRSLLTLLEYTPEEISFLLDLSAQVKRESRARIVHKRFAGKTLAMIFEKRSTRTRMAFETAFAEEGGHPIFLSIQDIQLGAKESIEDTARVLGRMVDAIMFRGYKQETVETLAKYSGVPVYNGLTDVYHPTQVLADLMTTQEVFGKLKGIKLVFMGDGRNNMANSLMIGCAKMGMHYVVCSPAELRPDENLMQTCLTIAKETDSKIEVIDDPEKAVDGADVIYTDVWASMGEESKQQERERLLRPYQVNEVLMRKTGKKDTIFLHCLPAVKGQEVTFDVIEGKQSRVWDEAENRKHTIKALMIATLL
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFHC2_MOUSE
Sequence: MALPFLPGNSFNRNIGKERFHKSQHWGFCNNVRMLVSENKPGVGGDLLYGQKIKPKHSVFPKGDGTDAPSWVAFDKQVLSFDAYLEDEISDKRQEIFRIRYYKIYFYLEDDTIQVNEPEVINSGLPQGTSIRRQRIPYPPPNDDQFYTVYDFNINISVVFYGRTFKIYDCDPFTKNFLKKIGIKLNPPGQCPLDPYMKMRRETLEFVDPFRPYQSFDTLKRFIQYDGKVLRFFCLWDDSTSLFGDRREFVLHYFLCDGTVEIREVLPSNSGRDAMSSFLRRGKLPKYGPPGIYQPGQITDRAVLNVYGGLSEWRADGYLLDKYQLGKVEQDFYTDQDLSIGATINVWGRKVLLCDCDEFTKTYYRTKYGVDNFTPISCKPPHLPKIERKYPPYTGFGSEEDSFRSCVGLKPTPHRKNFKKFMELDSFGNISNILRYFGKLITHKCADVDRIFVIAFYLSDDTISVFEPIENNSGNAGGMFLKRSRVKKPGQEVFKSEFSEYIKAEELYIGATVNINGYLFILLNADEYTLNYMENNTDKFPYSNFELAIQKLKQEKSKSREITQVFAAADYNHTKVVPYNTFRDILMSITMGKLIDQELITIARHYRVPEIMDPDLAYLIARAHEKFKKNIFENFDMFIYNCVYEDREKKGVLPTKDIRRMCKSSRLPLDDDFLDCLLSRFEDKDHQINYEIFFSVLNWRMNPTPDLQAPPYLKEKCEDVWVGMPSPIPVKYVRYLDFLIDVYGLEDNML
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
EF-hand domain-containing family member C2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: SYI_MICAN
Sequence: MSNAKSYKDTVNLPQTDFDMRANASKREPEIQKFWQDEQIYEKLAQNNPKELFILHDGPPYANGSLHIGHALNKILKDIINKYKLLQGYKVRYVPGWDCHGLPIELKVLQSLKSSEKEGLTPVKLRQKAHDFALQTQKEQCEGFKRYGVWGDWENPYLTLQPEYEAAQIAVFGKMALKGYIYRGLKPVHWSPSSQTALAEAELEYPEGHTSRSVYVAFPITSVSTPVLRPFLPNLSVAIWTTTPWTLPGNLAVALNPELNYSVVETSESNYLIVATDLVEKLADTFNRTLTIKATVKGLELEHTKYRHPLFDRESAILIGGDYVTTDSGTGLVHTAPGHGQEDYIVGQRYGLPILSPVDDKGNFTAEAGQFAGLNVLKDANEAIILALTEKGALLKEEAYQHKYPYDWRTKKPTIFRATEQWFASVEGFRELALEAIDSVRWIPATGKNRITSMVSERSDWCISRQRSWGVPIPVFYDEETNEPLLTEETINHVQAIFGVKGSNAWWELSVEELLPPSYRNNGRSYRKGMDTMDVWFDSGSSWNAVANARPELSYPADMYLEGSDQHRGWFQSSLLTSVAANGIAPYKTVLTHGFVLDEQGRKMSKSLGNVIDPNVIINGGKDQKKEPAYGVDVIRLWVSSVDYTNDVNIGQNILKQLVDIRNKIRNTARFLLGSLNDFDPVKDAVAYEDLPEIDRYMLHRISEVFTEVTAAFESFQFFRFFQTVQNFCVVDLSNFYIDIAKDRLYISDPNSFRRRSCQTVYAIALENLAKAIAPVLSHLAEDIWQFLPYKTPYLSVFESGWLNIDPAWNNRELADKWAKFRQLRTEVNKVMETARNDKAIGASLEAKVLLYVPDESLQQELELFNNCDSLTGNKVDELRYLFLSSQVELVSDISAIQTAEYKGESDFVSVGIVKAEGEKCDRCWNYSTQVGKFADDPTICERCNAALKGEF
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_STRPI
Sequence: MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAIQAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKGLNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSPQPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDFATNAGYGTAKHLEGLTKLGATPIHRTSFEPVKSLVLGKKES
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE6D_BOVIN
Sequence: MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
What is the function of this protein?
Promotes the release of prenylated target proteins from cellular membranes (PubMed:8798640).  Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity).  Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity).  Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity).  Increases the affinity of ARL3 for GTP by several orders of magnitude.  Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity).
What are the official names of this protein?
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, GMP-PDE delta.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, cilium basal body.
Protein: THIM_CHLCV
Sequence: MLEQMYEALQRLRKEKPVILNITNYVSMDFLANCFLAIGASPIMSVSDLELEELIGLSSAVYLNIGTLDHLFIQRSYRAVDIAIRQNKPIIFDPVGSGTTKIRTEVSHHLLAHSTIVRGNASKILSFGDLSIKTRGVDSANTTHDAKETAIALANECLCGCAIAVTGAVDFITDGKRSATIELGDPLMSHVTGMGCSLTGVLAAFRSVIDDSFEAARLGVEYFSLCGMLARERCEGPGLFKAYFLDELYAADFDRMRRYYEQ
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.