PharMolix/UniProtQA huggingface dataset:
Protein: HAS1_GIBZE
Sequence: MDFASSKKRKFKDANGVKPSKGKKSSSIPDKKSKKVKRAEPEPHDEPEDDSSDEEEQALKEVEDESDQADEDVEAANSAEEEEEEGGDEDNAENNTDLPNGGQLTLPPVAGAEAQSFEELKLSEKTMKAINEMKFTKMTEIQRRGIPPSLAGRDVLGAAKTGSGKTLAFLIPVIEMLSSLRFKPRNGTGVIVVSPTRELALQIFGVARELMAHHSQTYGIVIGGANRRAEAEKLAKGVNLLIATPGRLLDHLQNTPFVFKNLKSLVIDEADRILEIGFEDEMRQIIKVLPKEDRQTMLFSATQTTKVEDLARISLRPGPLYINVDEEKQYSTVEGLEQGYIICETDMRFLLLFSFLKRNLKKKIIVFFSSCACVKYHAELLNYIDLPVLDLHGKQKQQKRTNTFFEFCNAKQGTLICTDVAARGLDIPSVDWIIQFDPPDDPRDYIHRVGRTARGSNNKGRSLMFLQPNELGFLSHLKAARVPVAEFNFPTKKIINVQSQLEKLISQNYYLNKSAKDGYRSYMHAYASHSLRSVFDINKLDLAKVAKSFGFTQPPRVDITLGASMSRDKKQQGRRAYGSQPRQNQGNKFTR
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GUAA_PSEAB
Sequence: MSQDIHAHRILILDFGSQYTQLIARRVREIGVYCEIHPFDMSNEAIIAFAPRGIILAGGPESVHEADSPRAPQAVFDLKVPLFGICYGMQTMAEQMGGKVQGSDVREFGYARVDVVGKARLLDGIEDHVDDDGVLGLDVWMSHGDKVTEMPAGFHILASTPSCPIAAMADDARAYYGVQFHPEVTHTKQGLRILSRFVLDICGCAALWTPSNIVDDAIATVRAQVGSSKVLLGLSGGVDSSVVAALLHKAIGDQLTCVFVDNGLLRLHEGDQVMAMFAENMGVKVIRANAEDKFLGRLAGVADPEEKRKIIGRTFIEVFDEEATKLQDVKFLAQGTIYPDVIESAGAKTGKAHVIKSHHNVGGLPEDMQFELVEPLRELFKDEVRKIGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADLLRQADHIFIEELRAFDWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETIDFMTARWAHLPYELLEKVSNRIINEIAGISRVTYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: SYT_METS3
Sequence: MRILLIHSDYLNYNVKNKTPVAEEIEDAKKQGAFDESLVVFTAVEKDDENNPQGIVKNLVKEVIKTNDQVKAENIVLYPYAHLSSSLSSPKVAVQVLKDAEEALDAEGLNVKRVPFGWYKAFEISCKGHPLSELSRTITAEEEEEEEVEKKPSSWSILDGDKIIDIDDFKFENDQLEKLVSYELGTGASDAGEPPHVKLMREKELCDYESASDVGNLKWFPKGRLVRDLLADYVYNLVVDQGAMPIETPIFYDLDNEAINVHAAKFGERQYRTDTKKNLMLRFACCFGAFRVMADPFITWKNLPAKLYELSTYSFRFEKKGEVVGLKRLRAFTMPDFHSFCADMNSTLEEFSKQTDMCIQTGVDLDVNYEIIFRATKDFYDENKDWMYSIGKKIGKPVLLEILPERKHYWSCKIDFAAIDYLGRPIENPTVQIDVESGKRFDITYLGEDGKEHYPTILHCSPTGSIERVICSLLEKTAIELDEKAPMLPTWLSPIEVRIITVGEDHKDFANELYDKINAENIRVDVDDRDESVGKKIRNAATEWIPYIFVVGDNEKESGVFSVTVRETGEKVDMTVDELIKEILDKTKGMPYRGLPLPKDISTRINFQ
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHCT1_MOUSE
Sequence: MEASDWQGGEGDKPLEKVGSVPCLERSSSTVPTGDALVRHAKGLSQDTFKICKEYLRPLKKFLRKLNLPKDLPQKKRIKYTKQSLEALGGHINTFLQHYCRAWEIKHWKKMLWRFVSLFSELEAKQLRRLYKYTKTNQTAKFLAALCPLDAPERSLLANQEDCLPRLCSAWGLHGNISGMKERLSKMQAPGQEVVMLEEPRSSHCSRGDSLRKLPQKPKLKKKRIKERLESPKSCS
What is the function of this protein?
May play a role in regulation of apoptosis.
What are the official names of this protein?
CHD1 helical C-terminal domain containing protein 1, Uncharacterized protein C17orf64 homolog.
Protein: MTGA_SALHS
Sequence: MSKRRIAPLTFLRRLLLRILAALAVFWGGGIALFSVVPVPFSAVMAERQISAWLGGEFGYVAHSDWVSMADISPWMGLAVIAAEDQKFPEHWGFDVPAIEKALAHNERNESRIRGASTLSQQTAKNLFLWDGRSWLRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGIFGVEAAAQRYFHKPASRLSVSEAALLAAVLPNPIRYKANAPSGYVRSRQAWIMRQMRQLGGESFMTRNQLN
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DLDH_YEAST
Sequence: MLRIRSLLNNKRAFSSTVRTLTINKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEMLKTGHGHVNYNNIPSVMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAAYDKAIHC
What is the function of this protein?
Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.  This includes the pyruvate dehydrogenase complex, which catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  Acts also as component of the glycine cleavage system (glycine decarboxylase complex), which catalyzes the degradation of glycine.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, mitochondrial, Dihydrolipoamide dehydrogenase, Glycine decarboxylase complex subunit L, Lipoamide dehydrogenase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex E3 component.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CTAA_AGRVS
Sequence: MTIASTASPVPAAAGLDRQSRNRRALRLWLGLVILALFALVLVGGATRLTNSGLSITQWKPIHGVIPPLNAAEWEEEFKLYQQIPQYELVNKGMTVEAFKTIFWWEWAHRFLARSIGVIFALPLVFFWATGRIEKRLRWPLVGILALGGFQGFIGWWMVSSGLSERTEVSQYRLATHLVTACLIFSACVWVMRGLARHSADPAPTAHSRHWAIALLCLVLFQIYLGALVAGLDAGMSYNTWPLMDGALIPGDLLVQQPVWLNFFENPKTVQFVHRIGAYTVLLVALYHMVSSLRAAPGTTHARRSVVLFAIVCCQAVLGISALLLQVPLDAALAHQGGALILLGFTVAHLRGFYGAYPLPKPVA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBFA_COXB2
Sequence: MSQRQQRVADLIHQQLAELLKKEVRDSRLSKISLTAVSISPDLKQAKVFYSLLENQNEKEVQKALNKATGYLRHLLAQATVLRYVPKLEFVYDESIERAHRISFLIERALKKDDSDESS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCNR_ECOL5
Sequence: MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAAIRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK
What is the function of this protein?
Repressor of rcnA expression.  Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt.  In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity).
What are the official names of this protein?
Transcriptional repressor RcnR.
What is the protein family that this protein belongs to?
Belongs to the FrmR/RcnR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_ECO57
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPITWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVVELHKRLPSDWLLSAGLINGRNVWRADLTEKYVQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLCDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSMTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: ALD_METSP
Sequence: MTTIAAVSPLDGRLLGHFPVSKPALIQQQLTKSRRAALLWRELPVTERVKRLSPLKKQLLDNLDRLCETIRLSTGKVRTEALLGEIYPVLDLLAYYQKRAPRILRTRAVSTSPFAFPAATARIERRPYGVVAVISPWNYPFHLSVAPLLTALLAGNAVILKPSELCLPVGQLIVDLFATLDLPDGLVQWVIGDGQTGAELIDARPDLVFFTGGLQTGRAVMQRAARHPIPVMLELGGKDTMLVLADADLKRASAAALYGAFCNSGQVCVSVERLYVQQACFAEFLAMLLKGLSKLKVGHDPHGDVGVMTSARQIDIVQAHYEDAIAQGAKASGPLLRDGNVVQPVVLWDVHHGMKVMREETFGPLLPVMPFSDEAEAIKLANDSDLGLNASIWSQDIIKAERLAGQLDVGNWAINDVLKNVGHSGLPFGGVKQSGFGRYHGAEGLLNFSYPVSGLTNRSRLPKEPNWFPYSASGYENFKGFLDFIYGEDSMLQRGRRNQQALQAFREFSIFDWTQRWQNLKLLFSWTRDD
What is the function of this protein?
Involved in the biosynthesis of C30 carotenoids.  Catalyzes the oxidation of 4,4'-diapolycopene-4,4'-dial to yield 4,4'-diapolycopene-4,4'-dioic acid.  Also able to catalyze the oxidation of 4,4'-diapolycopen-4-al to yield 4,4'-diapolycopen-4-oic acid.
What are the official names of this protein?
4,4'-diapolycopene aldehyde oxidase, 4,4'-diapolycopenedial dehydrogenase, 4,4'-diapolycopenoate synthase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: APEX2_HUMAN
Sequence: MLRVVSWNINGIRRPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDALTEPLAIVEGYNSYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGNMDEFTQEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFYRLLQIRAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQSASHVGPFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVIDTFQASFLLPEVMGSDHCPVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHNNQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIELPSLPLMSALMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPLCGGHREPCVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLWSRPS
What is the function of this protein?
Functions as a weak apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents.  Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.  Also displays double-stranded DNA 3'-5' exonuclease, 3'-phosphodiesterase activities.  Shows robust 3'-5' exonuclease activity on 3'-recessed heteroduplex DNA and is able to remove mismatched nucleotides preferentially.  Shows fairly strong 3'-phosphodiesterase activity involved in the removal of 3'-damaged termini formed in DNA by oxidative agents.  In the nucleus functions in the PCNA-dependent BER pathway.  Required for somatic hypermutation (SHM) and DNA cleavage step of class switch recombination (CSR) of immunoglobulin genes.  Required for proper cell cycle progression during proliferation of peripheral lymphocytes.
What are the official names of this protein?
DNA-(apurinic or apyrimidinic site) endonuclease 2, AP endonuclease XTH2, APEX nuclease 2, APEX nuclease-like 2, Apurinic-apyrimidinic endonuclease 2, AP endonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the DNA repair enzymes AP/ExoA family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Note=Together with PCNA, is redistributed in discrete nuclear foci in presence of oxidative DNA damaging agents.
Protein: SYK_PROM4
Sequence: MSDLKETRLEKAQVLKKLGNGPYGIRFEVTHKAAVLQVEHQDLANGQERQLEVCVAGRVISRRVMGKLAFFTLSDESGSIQLFLEKATLEEHSDLDQESPGSFSQLTDLVDSGDWIGVNGILRRTDRGELSIKVFSWTMLCKSLQPLPDKWHGLSDVEKRYRQRYVDLIVNPQSRKTFRSRALMVSAIRRWLDERDFLEIETPVLQSEAGGAEARPFITHHNTLDLSLYLRIATELHLKRLVVGGFERVYELGRIFRNEGISTRHNPEFTTVEIYQAFADYTDMMDLTEEMISFVCSQICGSTTIQYQGKEVDLTPPWRRITMHELVLESTGLDFYEFGQDISKASTAMQSVGLNVPDHADSVGRLMNEAFEQAVEGDLFQPTFVMDYPIEISPLARKHRSKPGIVERFELFIAGRETANAFSELIDPVDQKERLLLQQSRRQAGDLEAHVIDEDFVNALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVIAFPLLKPESGSQ
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_LACE2
Sequence: MNRIEERLAALKEEGKKAFITYTTAGLPDYDTTKKIMFAQEKAGIDIMEIGVPFSDPIADGPVIQDASFKAIQNGASLEGIFTMMGKVRKAGLNSPVVFMLYYNTVYHYGVENFVNKCIENGVDGLIIPDLPFEEQGEIKDVLAKNEKSPILIQLVSPVSKGRIPMLLENARGFVYCVSQMGVTGKGANFHSQIREYLTEVKKESKIPVMMGFGIRTAADVAPLEDIIDGAIVGSHFIKLLEANNYSEEAATDYVATFKKELNA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: MENH_SALDC
Sequence: MMLHAQHMPGQPGTSSLVFLHGFSGDCREWQPVGEQFHGCSRLYIDLPGHGGSAAIPVGGFADVIRLLRATLISYNILKFWLVGYSLGGRVAMMAACQGIPGLCGLVVEGGHPGLQNEQARAERRLSDGRWAERFRHEPLTEVFHDWYQQPVFASLTAQQRQALTALRSQNNGETLAAMLEATSLAVQPDLREALNALAFPFYYLCGERDSKFRALAQEVAATCHVIRNAGHNAHRENPAGVVDSLAQILRL
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: GYRB_ACIPI
Sequence: DNSYKVSGGLHGVGVSVVNALSSKLHLIINRAGQVHEQEYHHGDPQYPLRVIGETDSSGTTVRFWPSELTFSQTIFNVEILARRLRELSFLNAGVRIVLRDERINLEHVYDYEGGLSEFVKYINEGKTHLNEIFHFTADTENGIGVEVALQWNESYQENVRCFTNNIPQKDGGTHLAGFRAALTRGLNQYLENENILKKEKVNVTGDDAREGLTAIISVKVPDPKFSSQTKEKLVSSEVKPAVEQAMNKEFSAYLLENPQAAKSIAGKIIDAARARDAARKAREMTRRKSALDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKQGRNRKMQAILPLKGKILNVERARFDKMISSQEVGTLITALGCGIGREEYNPDKLRYHKII
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_BREBN
Sequence: MKKIALLGSTGSVGTSTLEVVGQHPEDFSVVAMAAGTNIDLLTLQVETFKPELVSVGNEKAAVELRDRLAGKSQPEIVYGAEGLELVARHEAANFVMTAVVGSVGVAPTLAAIEAGKTIGLANKETLVSAGPVVMKRAKEKGVSIIPVDSEHSAVYQCLQGERMEDVAKIILTASGGSFRHLSREDLEQVTVEQALAHPNWSMGAKITIDSATMMNKGFEVIEAHWLFDLPYEQIECVLHYESIIHSMVEYKDRAVMAQLGTPDMKVPIQYAMSYPIRKKLPTEPLDLVKIATLHFAAMDYERYPLLKLAYECGMAGGTHTAVLNAANEVAVDMFLKGAIRFLDIEKVVRKTCEAHSGVASPELADIFAADEWARSYALVSI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MAA_BACSU
Sequence: MLRTEKEKMAAGELYNSEDQQLLLERKHARQLIRQYNETPEDDAVRTKLLKELLGSVGDQVTILPTFRCDYGYHIHIGDHTFVNFDCVILDVCEVRIGCHCLIAPGVHIYTAGHPLDPIERKSGKEFGKPVTIGDQVWIGGRAVINPGVTIGDNAVIASGSVVTKDVPANTVVGGNPARILKQL
What is the function of this protein?
Catalyzes the CoA-dependent transfer of an acetyl group to maltose and other sugars.  Acetylates glucose exclusively at the C6 position and maltose at the C6 position of the non-reducing end glucosyl moiety.  Is able to acetylate maltooligosaccharides.
What are the official names of this protein?
Probable maltose O-acetyltransferase, Maltose transacetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: RS8_DEIDV
Sequence: MLSDPIADMLTRIRNATRTHKETVDVPASNFKEQLANLLVAEGYVAGVERTRLDGQPADVLRLTLKYGAKREQVIKHIERISRPGRRAYVSAENLPRIQRGMGVAVVSTSKGLLPDREARKLGVGGEVICVLW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NU5C_SOLBU
Sequence: MEQTYEYAWIIPFIPLPVPMLIGAGLILFPTATKSFRRMWAFQSVLLLSIVMIFSIYLSIQQINSSSVYQYVWSWIINNDFSLDFGYLIDPLTSIMSILITTVGIMVLIYSDNYMAHDQGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGLCSYLLIGFWFTRPVAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFEIFNNLIYNNEVNFLFVTLCAVLLFAGAVSKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFRVIPYIMYLISVIGIITVLLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSIIHSMETIVGYSPAKSQNMGLMGGLRKHVPITKITFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIAWATAGLTAFYMFRIYLLTFEGHLNVHFQNYGGKHKTPFYSISLWGKNGVKKNSCLLTMNNNESTYFLSKTKYPIDKNGRKMTRPFMTIAHFEHKAVSSYPYESDNTMLFPIFVLGLFTLFVGAIGIPFNQEGVNLDILSKWLAPSINLLHPKSNNSQDWNEFLKDAVVSVSIAYFGIFIASFLYKPVYSSLKNLEFINSFVKKGPKRILWDKIINGIYDWSYNRAYIDAFYTRFFVGGIRGLAEFTHFFDRRVIDGMTNGVGVISFIVGEGIKYIGGGRISSYLFLYLAYVSVFLLVYYLLFSTF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: QUEA_SALA4
Sequence: MRVTDFSFELPESLIAHYPQPERSRCRLLSLEGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGTELLLGDDESIHATMTARHGALFEVEFNDPRPVLDILNAIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLAALREKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQEVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKRDLIEPFFGDTQIFIYPGYQYKVIDALITNFHLPESTLIMLVSAFAGYQHTMNAYKTAVEQKYRFFSYGDAMFITYNPQAISERP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFA2A_XENLA
Sequence: MWNNHGGFDGGYGGSGMGGGGGYMQSPGGFGSPAPTQGEKKSRSRSQQIVPCTVSQLLSATQNDEVFRIGEAELSQVTIVGIVRHAEKAPTNILYKVDDMTAAPMDVRQWVDTDEASCENMVVPPGSYVKVAGHLRSFQNKKSVVAFKIAPVEDMNEFVSHMLEVVHAHMAMNSQGAPSGGGSTVALSTPGRVGDSGRAFSGGNDNPTNGLTPHQSQILSLIKSCKGNEGMAFEELKNRLHGMNVNTIRQAVEFLSNEGHIYSTIDDEHYKCTDGD
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
What are the official names of this protein?
Replication protein A 32 kDa subunit-A, RP-A p32, Replication factor A protein 2, RF-A protein 2, Replication protein A 34 kDa subunit, RP-A p34.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Note=Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner.
Protein: FPG_ALKEH
Sequence: MPELPEVETTRRGLAPLLEGRRVTGMTVRQARLRWPVPAGLPDAITGQTIRAVDRRAKYLLFRTPAGTLILHLGMSGSLRVIPGQQAGACAVPPGRHDHVDLRLADGSCLRYTDPRRFGSLHWCTGEPEAHWLLHRLGPEPFDTAFDGDRLHRLSRGRRTSVKAFIMDSGIVVGVGNIYASESLFRAGIHPGRPAGRVGLARYRRLAGAVREVLAEAIAAGGTTLRDFTASDGRPGYFAQTLNVYGRAGAPCPRCGRSIRQRRIAQRSTWYCPGCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.