PharMolix/UniProtQA huggingface dataset:
Protein: HCP_AERHH
Sequence: MFCVQCEQTIRTPAGNGCAYAQGMCGKTAETSDLQDVLIYTLQGLSAWALAAREHGIVDSEIDAFVPKAFFATLTNVNFDSARIVAYVNQALTYRQQLAAKLAPLAVQADTLPAAARFEPGADLLAQLAQAPQTAVNRGKNEVNEDIMGLRLLCLYGLKGAAAYMEHARVLDQQDAGVAAEFHRIMSWLGTDPSDLDPLFKCAMDIGLLNFKIMEMLDLGETTAFGHPEPTQVRVTPVPGKCILVSGHDMVDLKLILEQTKGTGINIYTHGEMLPALAYPFFKQYPHLVGNYGSAWQNQQKEFANFPGAVVMTSNCIIDPNVGNYSDRIFTRSIVGWPGVTHLEGEDFSAVIAKAQALEGFKHVELEHFITIGFARNALMQAAPAVIDKVKAGEISHFFLVGGCDGDRAERAYYTEFAKAIPQDSLLLTLGCGKYKFNKLDFGDIGGIPRLLDVGQCNDAYSAIQLALALSEAFECGVNDLPLTLVLSWFEQKAIVILLTLLALGVKDIRTGPTAPAFLTPALLKVLEEQFGLKGTTTAEADLAEILAA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_RHOPA
Sequence: MTKSRAPKPPSDGTHPALGPLLTRWFFARSVHEVAPELIGATLLFGGAGGIIVEVEAYHHTDPAAHSYGGPTPRNQVMFGPPGFAYVYRSYGIHWCVNVVCEPEGSASAVLIRALEPTHGLAAMRKRRGLDEPRSLCSGPGKLAQALGITIADNGLPLDAAPFAIHRRTTTPEIVAGPRIGITKAADYPWRFGLKDSRFLSKPFPR
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: SYDND_CITBB
Sequence: MIDFLGDWKRSSYCGELRGGHIGQEVTLMGWVSKRRDHGGLIFVDLRDRDGISQIVFDPERCPEAHAKAESARNEYVLAIRGTVAARPEGTVNPKMKTGEIEVLVTECKLLNPSKALPFTLDGFVDVNENIRLKYRYLDLRTGTLQQNLMLRSKVAQLTRSYLSDNGFIELETPFLTKSTPEGARDFLVPSRINKGEFYALPQSPQLFKQILMVSGFDRYFQIVRCFRDEDLRADRQPEFTQIDCEMSFIDREDIITVMEGLMARIFTEARGVKVELPIERMTYQEAIRRFGVDNPDLRFGLELVELSDIVKNSGFKVFADVVNGGGIVKGMNVKGAGAMSRKEIDDLTEFAKIYGAKGLAYVKMTAEGWQSPIAKFFTPEEIATMDKAFDAKEGDLLLFVADKPKVVNDSLGKLRNHLAAKMGLTDPNVFRFVWITDFPLLEWDEEAKRWAAVHHPFTAPMDEDLQYVESDPGRCRAKAYDLVLNGNEIGGGSIRIHQEEVQSLMFKMLGLSEENARSKFGFLLDALEYGTPPHGGIAFGLDRLMMLITGSDSIRDVIAFPKTQKGACLMSDAPSGVDALQLRELGIRLAAK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOST_RAT
Sequence: MQLSLAPCLACLLVHAAFVAVESQGWQAFKNDATEIIPGLREYPEPPQELENNQTMNRAENGGRPPHHPYDTKDVSEYSCRELHYTRFVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRVKWWRPNGPDFRCIPDRYRAQRVQLLCPGGAAPRSRKVRLVASCKCKRLTRFHNQSELKDFGPETARPQKGRKPRPRARGAKANQAELENAY
What is the function of this protein?
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
What are the official names of this protein?
Sclerostin.
What is the protein family that this protein belongs to?
Belongs to the sclerostin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUSB_SACD2
Sequence: MKVSAAARGRARHFAMQALYQWEMSGNALHVIEAEFHTDNDMSKVDVEYFHEILHGVAAIKSTLDETFKPFLTGLRLDEIDPVSLAVLRQACYEFEKRVDVPYKVVINEAVNLAKKFGAADSHKFINGVLDKVALRVRKDEVEAMRTGRS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CRL5_ORYSJ
Sequence: MTNSNNGNGGTNAAASGWLGFSLSPHMASSTMDEHHHVHHHQQQQQQQQQQQHHQQQQHGLFFPSVTTAAAAAAYGLAGDVVAATNGYYSQLASMPLKSDGSLCIMEALRRTDQDHHGPKLEDFLGAAQPAMALSLDNTSSFYYGGGGAAAAGHGQHGYLQACDLYGGPAAPSLVTAADEEAAAAAAAMASWVAARGAATAYATGAADANAAENVLPSATAAQHLHHPLALSMSSGSLSSCITAGEYGMAAVAAADGGRKRGGAGGGGQKQPVHHRKSIDTFGQRTSQYRGVTRHRWTGRYEAHLWDNSCKKEGQTRKGRQGGYDMEEKAARAYDLAALKYWGPSTHINFPLEDYQEELEEMKNMTRQEYVAHLRRKSSGFSRGASMYRGVTRHHQHGRWQARIGRVSGNKDLYLGTFSTQEEAAEAYDVAAIKFRGLNAVTNFDITRYDVDKIMASNTLLPADLARRNAATTTSKDDHSAAGAGAIVSVHSAADIAVADTLWKATTAPRQQQQHHDDVVLSGADQAAFSVLHDLVAVDAAAAHQQQQQQQHMSMSAASSLVTSLSNSREGSPDRGGGLSMLFAKPSPAVAASAQQQASTKLMAAPLPLGSWVSSPPASARPPAVSIAHMPLFAAWTDA
What is the function of this protein?
Acts as positive regulator of adventitious (crown) root formation by promoting its initiation.  Promotes adventitious root initiation through repression of cytokinin signaling by positively regulating the two-component response regulator RR1.  Regulated by the auxin response factor and transcriptional activator ARF23/ARF1.
What are the official names of this protein?
AP2-like ethylene-responsive transcription factor CRL5, Protein CROWN ROOTLESS 5, Protein PLETHORA 8, OsPLT8.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: WAP_MOUSE
Sequence: MRCLISLVLGLLALEVALAQNLEEQVFNSVQSMFQKASPIEGTECIICQTNEECAQNAMCCPGSCGRTRKTPVNIGVPKAGFCPWNLLQTISSTGPCPMKIECSSDRECSGNMKCCNVDCVMTCTPPVPVITLQ
What is the function of this protein?
Could be a protease inhibitor.  May play an important role in mammary gland development and tissue remodeling.
What are the official names of this protein?
Whey acidic protein, WAP.
What are the subcellular locations of this protein?
Secreted.
Protein: ATGA1_RAT
Sequence: MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGIQDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEFYQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVMSRHEYLPKMPTQSELDNVFDTGLRDVQPYLYKISFQITEALGTSVTTTMRRLIKDTLAL
What is the function of this protein?
Autophagy factor required for autophagosome formation.  Stabilizes ATG13, protecting it from proteasomal degradation.
What are the official names of this protein?
Autophagy-related protein 101.
What is the protein family that this protein belongs to?
Belongs to the ATG101 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure. Note=Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
Protein: HIS1_ECOLU
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLMIRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S2512_PONAB
Sequence: MAVKVQTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGVISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ
What is the function of this protein?
Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (By similarity).  Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton.  Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (By similarity).
What are the official names of this protein?
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial, Solute carrier family 25 member 12.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS2_BARQU
Sequence: MALPDFTMHQLLEAGVHFGHQTHRWNPKMIRYIYGQRNNIHIIDLAQTVPLLHQALKLVSDTVARGGRILFVGTKRQASDIIADAANRSAQYYVNARWLGGMLTNWKTISNSIHRLRKLDKILATETQGFTKKERLNLERDREKLNRALGGIKDMGSVPDLIFIIDTNKENIAIQEAKRLGIPVIAIIDTNCNPDNVDHPIPGNDDASRAISLYCDLFARAALDGIARQQGAMGIDLGAQADAPVKPILENTIPVSE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PYRG_BORPA
Sequence: MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLQVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFISARMRKVNNFTTGQIYESVLRKERRGDYLGKTVQVIPHITNEIQDFVARGAEAAWNGATDVAIVEIGGTVGDIESLPFLEAARQMSLRMGRNNAAFVHLTLVPYIASAGELKTKPTQHSVQKLREIGIYPNVLLCRADRRIPDDERAKISMFSNVPLDAVISVWDVDSIYKIPAMLHKQGVDNIVCEALGLTPPPADLSMWDNLVDALEHPQDSVTIGMVGKYVDLTESYKSLSEALVHAGIHTRSKVNIEYIDSEDIETRGTDQLKHLDAILVPGGFGKRGTEGKIAAIRYARENGVPYLGICLGMQLAVIEFARHVAGLGGANSTEFDPAAPHPVVALITEWMDREGRVERRDNSSDLGGTMRKGAQRCPIRPGTRAQSIYGDDVNERHRHRYEVNNVYVPRLEDAGMVISARTPTENLPEMMELPSHPWFVGVQFHPEFTSTPRDGHPLFSSYIRAALEHKAQRAKEA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DUOX1_HUMAN
Sequence: MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIGTLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVLVYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEEERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF
What is the function of this protein?
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO.  Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa.  May have its own peroxidase activity through its N-terminal peroxidase-like domain.
What are the official names of this protein?
Dual oxidase 1, Large NOX 1, Long NOX 1, NADPH thyroid oxidase 1, Thyroid oxidase 1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the peroxidase family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Localizes to the apical membrane of epithelial cells.
Protein: CTTB2_ORNAN
Sequence: MATAGGSGQPLCSGPPARTSALPAKKEFDVDTLSKAELRMLLSVMEGELEARDVVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGEAEKKPVCTNPLSILEAVMAHCRKMQERMSAQLAAAESRQKKLEMEKSQLHVLQQEHRKLSARLEDERGKNKQVVLMLVKECKQLSSKVGEEGEKLEEAASKLDAEKRKTGELEGALSAERQKSSQMEARMEKQLSEFDTEREQLRAKLSREEALTADLREEIDKMRKTIEQLRKGNDHKPSLSLPRGKAKDRRSVSVSVGTEGPASRAAACQTDPVVEGADPVKKPPVAVPAKPSSAGPLASGTTKGGVGKPSVGRQFSHGDLLTSSSPSIPGPPRIQENGPSSGSTPEPTGSALMPLLNNAPPPAASQNHSLTSSTPNLHSPCANAASYPALNPRVQAARFRFQGNANDQDQNGNTTQSPPSREVSPTSRDNLVVRQLARNTVTQALSRFTGPQAGAPASPRAPHPGEGGTGPPSGGRASAKTPNAPRVDRGNPPPIPPKKPGLSQTPSPPHPQLKVLKDSGRPANAGAKVDSKTGVPPPSAPPHGIRVMNEENLAKSSSPQPPPKPAGDLAPAVPAGCALPAVAASQVGACLGCNPGPSQPACSESSHAIPTAIACSSSINPVSASSCAPWASHSLLVAASGWPPSLTPLLTSCGPVSLGGRPTRLHQAAAQGNVTLLSVLLNEEGLDINHACEDGSSALYSAAKNGHTDCVRLLLNANAQVDDADKNGFTPLCSAAAQGHVKCAELLIAYHADINHAAEGGQTPLYLACKNGNNECIKLLLEAGTDRSITTSDGWTPVHAAVDSGNVDSLTLLMYYGGPESENSGSKDQTGLGSREESRGAMPVISADLINQADKEGWTAAHIAASKGLKNCLEILCGHGRLEAERKDKCDRTAHDVATDDCKHLLENLNALKISVRISVGEKQPAVCGSDDFEAENTICALNIRKQTSWDDFSKAVSQAVTNHFQAISSDGWKRLEDLTFNNATESSVGLSVSSILSVKLGSVTWSTGQSFSQPPWDFLQKNKVEHVTVFLSGPQEGCLSSVTYASMIPLQMLQNYLRLVEQYHNVVFHGPEGSLQDYIAHQIALCLKHKQTAAGFPCEIVKAEVDTNFSKEQLVELFINSACLIPVKQPPVSKKVIVILENLEKASLSELLGDFLAPLENRSSENPYTFQKGNGVANSYYFHENCFLVGTIAKSCLQGSDLLVQQHFRWVQLRWDGEPIHGLLQRFLRRKVMNKFRGKVPSPCDPVCKIIDWILTVWHQLNSCLSRLGTPEALIGPRYFLSCPVVPGHAHVTVKWMSKLWNAVIAPKVQEAILSRASVKRPAVRPSPSQGQQAVVKAALSILLNKAILHGCPLPRAELDQYMAEFRSGCFPLSMVSSYSGSHRKKGESGSWRKVNTSPRKKSGLSSSQTWTKQEATKDGVRNDTGHQNGNSIASLVKQKSLENGHPQVLHLDQRLSLGSDDEVDLVRELQSMCSSKSESDISKIADSKDDFRMFGSSRTDPDPEFSPTMSDRSLPSSEKEVCPLSSNPTLECSNNTPKPESGVSRVKSFLPVPRNKVAQCSPNPKRSNSSSSSNTRQREINNNLKEEFWVLRKNIQ
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: RL23_DESAP
Sequence: MKFAHDILRKPLISEKSMSLTEGNKYTFIVDPRANKTEIKKAVEEIFKVKVLKVNTIRVKGKQVRRRNILGRKPETKKAVVTLRPGDKIEIFEGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MCTE_CERS5
Sequence: MAHQAHPFRSVLYIPGSKERALEKAQGLAADAIIFDLEDAVAHDEKIHARDLLRKTLETADYGRRIRIVRVNGMDTEWGRDDVAAFAGSKADVILIPKVSSATDVQAVADLIPDVPLWAMMETALGMLNAAEIAAHPRLTGMVMGTNDLAKELTSRFRPDRLALQTGLGLCLLAARAHGLTIVDGVYNAFKDEDGLRAECEHGRDMGFDGKTLIHPAQLEIANEVFSPSSAEIELANRQIAAFEEAERHGQGVAVVDGKIVENLHIVTARQTLAKAEAIAAFGAS
What is the function of this protein?
Catalyzes the hydrolysis of (3S)-malyl-CoA to (3S)-malate and free CoA.  Inactive towards beta-methylmalyl-CoA and other CoA esters (By similarity).
What are the official names of this protein?
(3S)-malyl-CoA thioesterase, (3S)-malyl-CoA thiolesterase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: ISPH_ANOFW
Sequence: MEVIKITPRGYCYGVVDAMVIARNAALNPTLPRPIYILGMIVHNKHVTDAFEEEGIITLDGPNRLEILENIDHGTVIFTAHGVSPEVKQRAREKGLVTIDATCPDVTKTHDLIREKVENGYEVIYIGKKGHPEPEGAIGVAPHAVHLIETPEDVEQLDIQSKRIIVTNQTTMSQWDVAHIMEKVKEKYPHVEMHREICLATQVRQEAVAEQAKEADVTIVVGDPRSNNSNRLAQVSEEIAGTKAYRVSDVTEIDIEWIKDAKKVAVTAGASTPTPITKEVIDFLEQFDPNNPETWKRERKVPLTKILPKVKKRGE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: DNAJ_MANHA
Sequence: MAKKDYYEVLGLSKGASEKDIKRAYKRLAAKHHPDKNQGSKESEEKFKEITEAYDVLTDSEKKAMYDQYGHAAFEQGGAGAGGFGGFGGGGFGGFEDIFSEMFGGGFGGGGRRQRVVRGDDLRYDIEITLEEAVKGCKKDIRIHTLAECDTCHGTGAEAGSKVETCSHCHGSGRIRRQQGFFVTDAVCPSCHGTGKRIEKPCRSCHGDGRVHKAKNLSVTIPAGVDTGNQLRLSREGAAGENGAPAGDLYVVIPVKEHDIFERDGSNLYCEVPIIFTLAALGGEIEMPTLDGQLKLKFRQKLQPVNYSVLRGKGVTSPRGGYAGDLICKVVVETPVNLTEEQKALLRQFEESLEGQGKHRPKHEGFFDGVKKFFDNLGK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSO_ECOLI
Sequence: MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
What is the function of this protein?
Mediates export of lysine.
What are the official names of this protein?
Lysine exporter LysO, Lys outward permease.
What is the protein family that this protein belongs to?
Belongs to the LysO family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VGFR3_COTCO
Sequence: MKRVCTLPLWLWLGIVSEADLVSSYSMTPPTLSITEEEHIINAKDTLTITCRGQHPLEWSWPGARWTPVEGRRRWNSQPQQRPVGAGNPEEDCEGTGTKPYCKVLVLTESQANDTGYYHCYYKYIDAKIEGTTAVSAYIFVRDFEQPFINKPETLLISKKENTWVPCLVSIPDLNVTLISQNSLIHPDRKTIFWDNKKGMQVPTQLIRDSLFVQCETVIDNKVFKSNFFIIHIAGIELYDIQLYPKKAMELLVGEKLVLNCTVWAEFNSGVRFQWTYPGKQMQRAVIESERRSLQTHTELSSILTLHNVSQQDLGRYTCTATNGAQMLEESTDVIVHEKPFINVEWRKGPVIEATAGDEAVKLPVKVVAYPQPDFQWYKAGKLIPKQSQSSMQIKDVAEHHAGTYTLVLRNRLVGLEKRISLQLIVNVPPRIHEKETSSPSIYSRRSPQALTCTVYGIPAPEVIQWQWRPWMPCRMFSRRSLNSRHRAARRHQRDRMPECKDWKDVSRQDAVNPIESIDTWVEFVEGRNKTVSKLAIQEANVSAMYKCIASNKVGRDERLIYFYVTTIPDGFEIESQPSEEPIEGQDLQLSCNADNYTYENLQWYRLNLSKLHDEEGNPLVLDCKNVHHYATKMQGELRFQPDSNDATLLLTIPNISLGEEGDYVCEVQNRKTREKHCHKKYISVQALEIPRLKQNLTDIWVNVSDSIEMRCKVDGNHVPDISWYKDEKLVEEVSGIDLADFNQRLSIQRVREEDAGLYLCSVCNAKGCVNSSASVSVEGSDDKTNVEIVILIGTGVIAVFFWILLIIIFCNIKRPAHADIKTGYLSIIMDPGEVPLEEQCAYLPYDSSKWEFPRDRLRLGKVLGHGAFGKVVEASAFGINKSNSCETVAAKMLKEGATASEQKALMSELKILIHIGNHLNVVNLLGACTKPNGPLMVIVEFCKYGNLSNYLRTKREGFSPYREKSPRLRIQVQSIVEAVRADRRSRSGTSDSAIFNRFLMHKSQTVQPIQEVDDLWQSPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRFKDGTRMRAPEYTTAEIYRIMLSCWHGDPKERPTFSDLVEILGNLLQENVQQEGKDYIPLNDSHSSEDDGFSQVPSSAQQNSDEEDFDMRIRCHSLAARYYNCVSFPGCLTGGNQIRCSSRIKTFEEFPMTHTMYKAHPDNQTDSGMVLASEEFERIENRHRKEGGFSSKGPNRTAELSAEQSDLRGRCRPSYGSQVGGQTFYNSEYGELSEHSEDRSCTPPAEGASPPALHASFFSEQY
What is the function of this protein?
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development.  Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting.  Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway (By similarity).
What are the official names of this protein?
Vascular endothelial growth factor receptor 3, VEGFR-3, Endothelial kinase receptor EK2, Quek 2, Quek2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Nucleus. Note=Ligand-mediated autophosphorylation leads to rapid internalization.
Protein: LFTR_ALISL
Sequence: MTIYLPELEQEHDASFPDIESALHDPDGLLAMGGDLTPKRLLLAYSHGIFPWYSNDDPILWWSPSIRGVFIPENYTPSKSLKKFFKKSGYSITINHATSDVISLCASTRPAEETWIMPEMIEAYQNLAKLGHCHSVEVWFNNELVGGLYGLQIGQVFCGESMFSIKTNASKIALWKFCEHFVAFGGKLIDCQMMNPHLESLGAIPMERPIFNERLQVFSAISVFENCYQPQSLSNG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_STRP6
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLNDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJJB_SALNS
Sequence: MGIIDFLLALMQDMILSAIPAVGFAMVFNVPHRALPWCALLGALGHGSRMLMMSAGFNIEWSTFMASLLVGSIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISHLGYSEPMMITLLTNFLKASSIVGALSIGLSVPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.