PharMolix/UniProtQA huggingface dataset:
Protein: PYRF_SINMW
Sequence: MSARDRLIVGLDLPTLAEAEKIVSALGEEVLFYKIGYQLAFAGGLDFARDLAASGKQVFLDMKLLDIDNTVAKGVENIVKMGVSMLTLHAYPKAMKSAVEAARGSNLCLLAVTVLTSMDEQDVMDAGYNYDPQSLVLRRAEQAHAAGMGGIVCSAAEAAAVRKIIGGDMALVTPGIRPAGAEKGDQKRVMTPADALAAGSSHLVVGRPIVAAPDPLAASRAILAEMESALSG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: METE_ECOSE
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHNVKPVLLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RS19_LACDB
Sequence: MSRSIKKGPFADAHLLKKVDEQQAAEKKQVIKTWSRRSTIFPSFVGLTIAVYDGRKHVPVFVTEDMVGHKLGEFVPTRTFRGHKADDKASK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ACPS_ARTS2
Sequence: MIVGIGVDVVDIERFGRQLERTPGLRDRLFVPAERELNTRSLAARFAAKEAVAKVLGAPAGMNWQDCWIGLDQNGPTIQVKGTVLAVAESKGVKRWHLSMSHDGGIATATVLAEG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_THESQ
Sequence: MIYYGTMFDHKVRFSIVRMREVVEEARNRHVLSYLATVVLGRALIGAALVTPWLAEKERWTLDIEGSGPIRRVVAQSTSEFTVRGYVANPKVELPLNEKGKFDVAGAIGQGVLRVVRDLGLKTPFVSQVPLVSGEIAEDLAYYFAVSEQIPSAFSIGVLVDSGGVKIAGGFAVQIIDRTLEQEKVELIERNIKNLPYITELFQKAEPLDVLERIFGEKVGFVETAEIRYKCDCNREKAKNALLVLDKKELEDMRKEGKGEVVCKWCNTKYVFSEEELEELLKFKVDNSGS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2042_VIBCM
Sequence: MSKNDHRITHNKSDKDNLDDDFSLFRDEVKGVKKLRQDTILHAPNRNPKQKEIRRTEREASDNDFYFSDEFMPHLTDEGPTRYARSDVSKYEVKRLRRGVYVPDVFLDMHGMTQQEAKRELGAMIAYCLKENVHCACVQHGIGKHILKQNVPLWLAQHPDVLAFHQAPLEFGGDGALLVLLSIPEK
What are the official names of this protein?
UPF0115 protein VCM66_2042.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: CBPY_YEAST
Sequence: MKAFTSLLCGLGLSTTLAKAISLQRPLGLDKDVLLQAAEKFGLDLDLDHLLKELDSNVLDAWAQIEHLYPNQVMSLETSTKPKFPEAIKTKKDWDFVVKNDAIENYQLRVNKIKDPKILGIDPNVTQYTGYLDVEDEDKHFFFWTFESRNDPAKDPVILWLNGGPGCSSLTGLFFELGPSSIGPDLKPIGNPYSWNSNATVIFLDQPVNVGFSYSGSSGVSNTVAAGKDVYNFLELFFDQFPEYVNKGQDFHIAGESYAGHYIPVFASEILSHKDRNFNLTSVLIGNGLTDPLTQYNYYEPMACGEGGEPSVLPSEECSAMEDSLERCLGLIESCYDSQSVWSCVPATIYCNNAQLAPYQRTGRNVYDIRKDCEGGNLCYPTLQDIDDYLNQDYVKEAVGAEVDHYESCNFDINRNFLFAGDWMKPYHTAVTDLLNQDLPILVYAGDKDFICNWLGNKAWTDVLPWKYDEEFASQKVRNWTASITDEVAGEVKSYKHFTYLRVFNGGHMVPFDVPENALSMVNEWIHGGFSL
What is the function of this protein?
Vacuolar serine-type carboxypeptidase involved in degradation of small peptides (PubMed:8679540).  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (PubMed:8679540).  Also plays a role in breakdown of the autophagic body and the autophagosome-dependent protein synthesis (PubMed:29514932).  Plays a key role in phytochelatin (PC) synthesis from glutathione (GSH) by cleaving the Gly from GSH and form the PC-peptides of the structure (gamma-Glu-Cys)2-Gly (PubMed:17408619).  Also involved in resistance to xenobiotics via the degradation of glutathione-S-conjugates (PubMed:19897216).
What are the official names of this protein?
Carboxypeptidase Y, CPD-Y, cpY, Carboxypeptidase YSCY.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole lumen. Note=The vacuolar sorting receptor VPS10 is required for the delivery of ATG42 to the vacuole lumen.
Protein: MRAY_HYDCU
Sequence: MLIYLTDYLSQYISGFSVFHYITMRTIMSVLTALLISFVIGPRVIRWLIRLKVGQSIRLDGPETHLIKTGTPTMGGVMILFSVSSAILLWGNLTNHYLLIATLTMLGFGVIGFVDDYKKVVYKDPNGMRSRTKFFWQSVVGLVAAFTLYSLAKVPAETQLLIPYMKDTFIYLGAWTVVLAYFVIVGTSNAVNLTDGLDGLAIMPTVMVAGALGVFAYMTGHLYFSDYLQIPYIPGVGELAIFCAALVGAGLGFLWFNAHPAQVFMGDVGSLAIGAALGVVAVAVRQELVLFIMGGIFVAETLSVILQVGSYKLRNGKRIFLMAPLHHHFEQKGWHESQVIVRFWIITILLVLIGLASLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL28_DICNV
Sequence: MSRICQVTGKKPMVGNTVSHANNKGKRRFLPNIQEHRFWVQSENRFITLKVSAHGMRIIDKKGIDAVLAQMRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: VPB13_MYCTO
Sequence: MSKRLQVLLDPDEWEELREIARRHRTTVSEWVRRTLREAREREPRGDLDMKLRSVRAAARHEFPTADVEQMLEEIERGRGAEREGSR
What is the function of this protein?
Putative antitoxin component of a possible type II toxin-antitoxin (TA) system.  The cognate toxin is VapC13 (By similarity).
What are the official names of this protein?
Putative antitoxin VapB13.
Protein: GUC1C_HUMAN
Sequence: MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDKAGLGKVKMK
What is the function of this protein?
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated.  This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
What are the official names of this protein?
Guanylyl cyclase-activating protein 3, GCAP 3, Guanylate cyclase activator 1C.
Protein: RL11_ECO7I
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: H2A2_CANGA
Sequence: MSGGKGGKVGSAAKASQTRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKPSASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HECW2_HUMAN
Sequence: MASSAREHLLFVRRRNPQMRYTLSPENLQSLAAQSSMPENMTLQRANSDTDLVTSESRSSLTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGGASGNLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAIGDQMLSYNLGRRLPADHVSGYLQFKVEVTSSVHEDASPEAVGTILGVNSVNGDLGSPSDDEDMPGSHHDSQVCSNGPVSEDSAADGTPKHSFRTSSTLEIDTEELTSTSSRTSPPRGRQDSLNDYLDAIEHNGHSRPGTATCSERSMGASPKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEAASFEDKPENLPELAESSLPAGPAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGTCEGATAQEEGATGGSQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTNAIDGAGEEADFHQASADFRRENILPHSTSRSRITLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRPQYQDMVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73.  Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487).  Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370).
What are the official names of this protein?
E3 ubiquitin-protein ligase HECW2, HECT, C2 and WW domain-containing protein 2, HECT-type E3 ubiquitin transferase HECW2, NEDD4-like E3 ubiquitin-protein ligase 2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle.
Protein: GSA2_BACC3
Sequence: MKKFDKSIAAFEEAQDLMPGGVNSPVRAFKSVGMNPLFMERGKGSKVYDIDGNEYIDYVLSWGPLIHGHANDRVVEALKAVAERGTSFGAPTEIENKLAKLVIERVPSIEIVRMVNSGTEATMSALRLARGYTGRNKILKFIGCYHGHGDSLLIKAGSGVATLGLPDSPGVPEGVAKNTITVAYNDLESVKYAFEQFGDDIACVIVEPVAGNMGVVPPQPGFLEGLREVTEQNGALLIFDEVMTGFRVAYNCGQGYYGVTPDLTCLGKVIGGGLPVGAYGGKAEIMRQVAPSGPIYQAGTLSGNPLAMAAGYETLVQLTPESYVEFERKAEMLEAGLRKAAEKHGIPHHINRAGSMIGIFFTDEPVINYDAAKSSNLQFFAAYYREMVEQGVFLPPSQFEGLFLSTAHSDADIEATIAAAEIAMSKLKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_SHESW
Sequence: MPKLRSATSTEGRNMAGARALWRATGVKDNDFGKPIIAIANSFTQFVPGHVHLKDMGSLVASAIEEAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKTKLSDKLIKLDLVDAMVAGADSNVSDEDSAKIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADRRELFLEAGRRVMALAKRYYHQDDESALPRNIANFKAFENAMTLDIAMGGSSNTVLHLLAAAQEADVDFTMADIDRMSRLVPHLCKVAPSTPKYHMEDVHRAGGVMGILGELDRAGLLHTDVFHVAADEGGNLKSVLAKYDVMQTQDEKVKHFFMAGPAGIPTTKAFSQDCRWPSLDNDRQEGCIRSREFAFSQEGGLAVLSGNVAENGCIVKTAGVDESNLTFVGSARVYESQDDAVAGILGGEVVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSRGLGKACALITDGRFSGGTSGLSIGHVSPEAAAGGTIALIENGDRIEIDIPKRSIKLALTDAELAARREAMLARGPMAWKPIGRERFVSLALKAYAMLATSADKGAVRDRSKLED
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: Y1330_SHESW
Sequence: MESLQNHFLIAMPSLDDTFFERSVIYLCEHDDKGAMGIVINKPLGIEVSSLLEQMDLPAEQVFADIAQNAQVLMGGPVSQDRGFVLHTSQPYWANSTDLGSGLMLTTSRDVLTAIGGKRSPDKFLVALGYAGWGKHQLEQELAENSWLTIPATNALLFDVKHEDRWPQASRSLGFDAWQVSAQAGHA
What are the official names of this protein?
UPF0301 protein Sputw3181_1330.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL32_DROPE
Sequence: MTIRPAYRPKIIKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHAVSSKKRKEIVERAKQLSIRLTNPNGRLRSQENE
What are the official names of this protein?
60S ribosomal protein L32, Ribosomal protein 49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: Y534_CUPMC
Sequence: MDNRLLEILVCPLCKGKLEYDRAAQELICHADKLAYPIRDGIPVMLADEARQTVPGRVVPVEPSAPAGN
What are the official names of this protein?
UPF0434 protein Rmet_0534.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: CYSG_NITEU
Sequence: MDYLPVFLNIKQRDCLVVGGGEIAVRKIRLLLRAHARIHVVSPAISEELSNLLLQSPVITHTAESFRPDHLQDRALAIAATNDHEVNRAVSAAARKAGIPVNVVDNPDLCTFIMPSILDRSPIIVAVSSGGTSPILARLLRSRLEALIPSAYGRLAEYAARFRDKVRQRFIHQENRRFFWERMLQGPFAEMVFAGRDQAAQDYLSEALENSTDQFPTGEVYLVGAGPGDPDLLTFRAMRLMQQADVVIYDRLVSPAILDMVRQDATRIYVGKVRNQHTLPQTSINELLVKLAQEGKHVLRLKGGDPFIFGRGGEEIETLSQHHIPFQVVPGITAASGVASYAGIPLTHRDHAQSCVFVTGHLKDNTIQLDWPALARPNQTIVVYMGLLGVTELCRQLIAHGLQATTPAAIVQQGTTPNQRVLTGTLETLPDIIQQNPLKPPTLIIVGNVVKLHQKLAWFNSTSEPMGTSSGPGYP
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: CLPS2_RHOPA
Sequence: MAGDGGRSGPSTPSTSVITKTKPRTKRPNLYRVLILNDDYTPMEFVVHVLEKFFQMDVEAATKVMLHVHHHGIGECGVFTYEIAETKVTQVMDFARKHQHPLQCVMEKK
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS 2.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: TODA_PSEP1
Sequence: MATHVAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLPYDRPSLSKAVLDGSLERPPILAEADWYGEARIDMLTGPEVTALDVQTRTISLDDGTTLSADAIVIATGSRARTMALPGSQLPGVVTLRTYGDVQVLRDSWTSATRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGRRIGAWLRGLLTELGVQVELGTGVVGFSGEGQLEQVMASDGRSFVADSALICVGAEPADQLARQAGLACDRGVIVDHCGATLAKGVFAVGDVASWPLRAGGRRSLETYMNAQRQAAAVAAAILGKNVSAPQLPVSWTEIAGHRMQMAGDIEGPGDFVSRGMPGSGAALLFRLQERRIQAVVAVDAPRDFALATRLVEARAAIEPARLADLSNSMRDFVRANEGDLT
What is the function of this protein?
Part of the electron transfer component of toluene 1,2-dioxygenase, transfers electrons from ferredoxin (TodB) to NADH.
What are the official names of this protein?
Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: CALU_MESAU
Sequence: MDLRQFLLCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFDQLTPEESKERLGKIVSKIDDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFPHPDEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNADEPEWVKTEREQFVEFRDKNRDGRMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
What is the function of this protein?
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues.  Seems to inhibit gamma-carboxylase GGCX.  Binds 7 calcium ions with a low affinity (By similarity).
What are the official names of this protein?
Calumenin.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen.
Protein: MNMA_SHESR
Sequence: MTSIEPTHTGKKVIVGMSGGVDSSVSAYLLMQQGYQVEGLFMKNWEEDDNDEYCAAAEDLKDAQAVCDKLGIKLHTVNFAAEYWDNVFEYFLAEYKAGRTPNPDIMCNKEIKFKAFLDFADDILDADYIAMGHYVRRRDNADGTTQMLRGVDNNKDQSYFLYTLSHEQVARSLFPVGELEKHEVREIAKKMGLITHDKKDSTGICFIGERKFTEFLGNYLPAQPGNIETAEGEVIGKHQGLMYHTLGQRKGLGIGGMKNSNDDPWYVVDKDLKRNVLVVGQGGHHPRLMSNGMFVNQLHWVDRKGPVEGSQIVVKTRYRQQDIPCTLTYLDDNTLKVVFDEPVAAVTPGQSAVFYDGDVCLGGGIIDQLIRG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTI1_HUMAN
Sequence: MAVFDTPEEAFGVLRPVCVQLTKTQTVENVEHLQTRLQAVSDSALQELQQYILFPLRFTLKTPGPKRERLIQSVVECLTFVLSSTCVKEQELLQELFSELSACLYSPSSQKPAAVSEELKLAVIQGLSTLMHSAYGDIILTFYEPSILPRLGFAVSLLLGLAEQEKSKQIKIAALKCLQVLLLQCDCQDHPRSLDELEQKQLGDLFASFLPGISTALTRLITGDFKQGHSIVVSSLKIFYKTVSFIMADEQLKRISKVQAKPAVEHRVAELMVYREADWVKKTGDKLTILIKKIIECVSVHPHWKVRLELVELVEDLLLKCSQSLVECAGPLLKALVGLVNDESPEIQAQCNKVLRHFADQKVVVGNKALADILSESLHSLATSLPRLMNSQDDQGKFSTLSLLLGYLKLLGPKINFVLNSVAHLQRLSKALIQVLELDVADIKIVEERRWNSDDLNASPKTSATQPWNRIQRRYFRFFTDERIFMLLRQVCQLLGYYGNLYLLVDHFMELYHQSVVYRKQAAMILNELVTGAAGLEVEDLHEKHIKTNPEELREIVTSILEEYTSQENWYLVTCLETEEMGEELMMEHPGLQAITSGEHTCQVTSFLAFSKPSPTICSMNSNIWQICIQLEGIGQFAYALGKDFCLLLMSALYPVLEKAGDQTLLISQVATSTMMDVCRACGYDSLQHLINQNSDYLVNGISLNLRHLALHPHTPKVLEVMLRNSDANLLPLVADVVQDVLATLDQFYDKRAASFVSVLHALMAALAQWFPDTGNLGHLQEQSLGEEGSHLNQRPAALEKSTTTAEDIEQFLLNYLKEKDVADGNVSDFDNEEEEQSVPPKVDENDTRPDVEPPLPLQIQIAMDVMERCIHLLSDKNLQIRLKVLDVLDLCVVVLQSHKNQLLPLAHQAWPSLVHRLTRDAPLAVLRAFKVLRTLGSKCGDFLRSRFCKDVLPKLAGSLVTQAPISARAGPVYSHTLAFKLQLAVLQGLGPLCERLDLGEGDLNKVADACLIYLSVKQPVKLQEAARSVFLHLMKVDPDSTWFLLNELYCPVQFTPPHPSLHPVQLHGASGQQNPYTTNVLQLLKELQ
What is the function of this protein?
Regulator of the DNA damage response (DDR).  Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins.  The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC).  Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.  Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
What are the official names of this protein?
TELO2-interacting protein 1 homolog, Protein SMG10.
What is the protein family that this protein belongs to?
Belongs to the tti1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG8G_ARATH
Sequence: MSNVSFRQDHDFEKRKAEALRIREKYSDRVPVIVEKSEKSDIPNIDKKKYLVPADLTVGQFVYVIRKRIQLSAEKAIFIFVDNVLPPTGAMMSTIYDENKEEDGFLYVTYSGENTFGSSMT
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
What are the official names of this protein?
Autophagy-related protein 8g, Autophagy-related ubiquitin-like modifier ATG8g, AtAPG8g, Protein autophagy 8g.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Cytoplasm, cytoskeleton.
Protein: VPS26_CAEEL
Sequence: MAMLFGFGQSAEIQIRLSNEDTRKIVKARGDDGNMHDHFLYYDGESVTGTVHVNLKKANHKFEHQGIRIEFIGQIEVYYDRGNQQDFISLTRELARPGDLTQNAQFPFEFNNVEKPFETYMGTNVKLRYFLRVTVIRRLTDLTKELDLVVHALSSYPDNDKSIKMEVGIEDCLHIEFEYNKNKYHLQDVIVGKIYFLLVRIKIKYMEIAILKTEVVGSGPNTFKESETVAKFEIMDGAPVRGESIPIRLFLAGYDLAPSMRDVGKKFSVKYFLNLVLVDEEDRRYFKQQEVTLWRKADKVMRRPGTEDDEEEKQTTSIPGTQKFTAPAPVEHPKPESPRSDPKSGSTSPDDNSDSS
What is the function of this protein?
May play a role in vesicular protein sorting, similar to the yeast retromer proteins.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 26, VPS26 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS26 family.
Protein: Y5584_VIBPA
Sequence: MKLIKPLTCALALAMSGMAFADVTVSVPDDVSVLAANGEKAKLSGGFFASEKALTLPDGVNQVVFRYAPYFNQGNDRLSVESDVIVARFDTANAELTIEVPKYRNMRDAEENIKDLDWKLVDGSGKAVAVDQDKLIKPGMQIGRDYVREIEDYNRAGGTAAVAFAGAATMQPVTLPAKIPEDMKQARATAVKADSTAEEMLHFWYQKADAETKARFKAYINQQ
What are the official names of this protein?
UPF0319 protein VPA1584.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: HSLV_AGRVS
Sequence: MSEHNPYGTMHGTTIITVRKGGMVVMAGDGQVSLGQTVMKGNARKVRRIGKGEVIAGFAGATADAFTLLERLEKKLEQYPGQLMRAAVELAKDWRTDKYLRNLEAMMLVADKTVTLAITGNGDVLEPEHGTIAIGSGGNYALAAALALMDTEKSAEEVARKAMKIAADICVYTNENVLVETLESAN
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.