PharMolix/UniProtQA huggingface dataset:
Protein: DPM2_HUMAN
Sequence: MATGTDQVVGLGLVAVSLIIFTYYTAWVILLPFIDSQHVIHKYFLPRAYAVAIPLAAGLLLLLFVGLFISYVMLKTKRVTKKAQ
What is the function of this protein?
Regulates the biosynthesis of dolichol phosphate-mannose (PubMed:10835346).  Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1 (PubMed:10835346).  Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis (PubMed:16162815).  May act by regulating the GPI-GNT complex (PubMed:10944123).
What are the official names of this protein?
Dolichol phosphate-mannose biosynthesis regulatory protein, Dolichol-phosphate mannose synthase subunit 2, DPM synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DPM2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CB081_MOUSE
Sequence: MSHEGSRQARDRGVTRSKAEKARPPTQPVPQVDIVPGRLNEAEWIAFMSLEEGEDVVGDILADLMTRVMECAFKVYLTQQCVPFTISQAREAMLQITEWRFLARDEGESAVAEDPTWGEDEEPLACTTDSWAQGSVPVLHTPAPVCVEEQFHNEEPGNPDQFLLGSSWDKESQKPTQPSEPSAEPKVTPRPTATLEAFEEAEPGDALEVPHGQEGSHMLAVPSKESLRSTAEGERVYSPQSSLKQPQVVRLQASEKESSFGSHLSLEDLYLCMPQPDAAGDRLSLQSKGQLHSSPIGSESHLGALTPAEPSAFQEPEVLGERPKHKTTTLRMDSSRLPRHWVRPVAEVLIPDLEVHPLEIYRGRPRRSQAGTATSACESQALSSRAPSKPHVSSPRFPLQRCATFRALGPDPSLNLAQTSPSFGSNVPFLSPGFRFLPRNPIPPDVASTPTPKLWPLAKWPSGWEREAEQLGELWAGRTRVPPQGQEPVEVTPLEEDSGWPLAAPQVLEATSQVLWKPMVISETMKLVPGVSMWNRGTQELLNPAVIRKEAEEGTPQAPEQQPIQTGVSKPQVIMKQIRNETPKAWLLPTKPVPHSGS
What are the official names of this protein?
Uncharacterized protein C2orf81 homolog.
Protein: IXTPA_STAAR
Sequence: MKEIVIASNNQGKINDFKVIFPDYHVIGISELILDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDRTMAQLSKEQKGQISHRRNAINLLEAYLAGDQNV
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: TAF5_ENCCU
Sequence: MSENIRESISAKTLSKDQMETSYVSLKTWIEDSLDLFKNDLLPLLYPLFIHIYFDLIQQNKTDEAKEFFEKYRGDHYNKSEEIKQFESIYTVQHIHENNFAYTFKNSKYHLSMGRYAFDLLINFLEERNLTYILKILNQHLDIKVYVGPKSEERPQGIETSVVDAEIDLTTFLVSRECEDAILGDEQYRYDHLETYVLQLRKQREMKPKDSVYKPNASQIHAEIEKLKDLCKRVAVNKNNLPSICCYTIHNTYEGLTAAEISNDLKLMACGFKDSYVEVYSLTNESLKKLKSSSELAKSDIKTLNEEKFEEVGSSYKLVGHSGPVYGLKFFSSNKFLVSSSQDCTVCLWSLDLLCLLAVYKAHAFPVWCVDVAPNDYFFASGAGDRQAIVWSVMTSKPERLIISSLSDVTAVKFHPNSSYLFTGSSDHRVRMHDISTASVVRIFCGHTDTVTCMDVSHCGKFLASGSKDRTVLLWDIQSSKLLGKYVGHENTVFSVSFCFYGSVLASCGADNSVRLWDRTDHKGGCLGTYYTKNTPLLCVKFGYRNIISCTGPFIS
What is the function of this protein?
TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription.  Regulates the genes involved in ubiquitin-dependent proteolysis during the progression of M-phase of mitosis (By similarity).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TAF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMD_PSYIN
Sequence: MWIGVVSLFPDMFRAISDNGVTGRAVKNKLLSIQCWNPRDFTLDKHRTVDDRPYGGGPGMLMMVKPLRDAILAAKKAAREAGHEAKVIYLSPQGKRLDHCGAQLLSGSDALILVAGRYEGVDERLIESLVDEEWSVGDYVLSGGELPAMILIDAVVRFVPGVLGHVLSAEQDSFADGLLDCPHYTRPEVLDGKQVPSVLLSGDHEKIRLWRSKQALQRTKQRRPDLLNNLALTDEQAKLLAALESDSD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSD_ECOLI
Sequence: MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_MYCSS
Sequence: MSGGAGVPDLPQIDASGMKVGIVASTWHSTICDALLDGALKVTESANVSEPTVVRVLGAIEIPVVAQALAADHEAVIALGVVIRGQTPHFDYVCDAVTQGLTRVSLDASTPVANGVLTTNTEEQALDRAGLPGSAEDKGAQAAAAALSTALTLQGLRGRS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y962_STAAT
Sequence: MRLYINEIKIKDDILYCYTEDSIKGLSEVGQMLVDSDNYAFAYTLDDGKAYAYLIFVQETWTMLHENMTKKIIINDELELTEFHQELTYILDNIKGNNNYGKEFVATVEETFDIE
What are the official names of this protein?
UPF0738 protein USA300HOU_0962.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: LEU1_XANOR
Sequence: MNTTISNQTPHIRIFDTTLRDGEQSPGCSMTPQQKLVMARALDALGVDIIETGFPASSHSDREAVAMMGRELRRPTLAVLSRCLQADIETSARALETVANPRLHVFLSTSPLHREHKLRMSREQVLESVHRHVTLARGYIDDVEFSAEDATRTEEDFLAEVTRVAVAAGATTINLPDTVGFTTPEEIRGMFSRLIASVEGADKVIFSAHCHNDLGLAVANSLAAIEGGARQVECTINGIGERAGNCALEEITMALKVRGAFYNIDSAINTPRIVSTSQLLQRLVGMPVQRNKAVVGGNAFAHESGIHQHGMLRHRGTYEIMRPEDVGWESSQMVLGRHSGRAAVERRLRALGYLLEEEEVKLMFEQFKALCEKQRLVTDADLQALMQDATVQEGYRLASMTISDVGSRANALVELSDPEGNRVAETAQGNGPVDALFGALASATGVKLELDSYQVHSVGIGADARGEASLSVRHDGVEYEGTGTSKDIIEASALAWLDVANRLLRQRERGVIAGKTAAVA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: COFD_METAC
Sequence: MIILSGGTGTPKLLDGLKEILPLEELTVVVNTAEDLWVSGNLISPDLDTVLYLFSDQIDRKKWWGIENDTFRTYERMHELGIEESMKLGDRDRATHIIRSNLIRGGTSLTEATVKLASLFGIDANILPMSDDPVSTYVETLQGVMHFQDFWVGKHGDPDVLGVDIRGVSEASVAKKVLEAFEKDDNVLIGPSNPITSIGPIISLPGMRELLKRKKVIAVSPIIGNAPVSGPAGKLMQACGLEVSSMGVAEYYQEFLDVFVFDERDRADEFAFERLGCRASRADTLMTSTEKSRELAEFVVGLFDTVC
What is the function of this protein?
Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
What are the official names of this protein?
2-phospho-L-lactate transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: RPP40_HUMAN
Sequence: MATLRRLREAPRHLLVCEKSNFGNHKSRHRHLVQTHYYNYRVSFLIPECGILSEELKNLVMNTGPYYFVKNLPLHELITPEFISTFIKKGSCYALTYNTHIDEDNTVALLPNGKLILSLDKDTYEETGLQGHPSQFSGRKIMKFIVSIDLMELSLNLDSKKYERISWSFKEKKPLKFDFLLAWHKTGSEESTMMSYFSKYQIQEHQPKVALSTLRDLQCPVLQSSELEGTPEVSCRALELFDWLGAVFSNVDLNNEPNNFISTYCCPEPSTVVAKAYLCTITGFILPEKICLLLEHLCHYFDEPKLAPWVTLSVQGFADSPVSWEKNEHGFRKGGEHLYNFVIFNNQDYWLQMAVGANDHCPP
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648).  Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
What are the official names of this protein?
Ribonuclease P protein subunit p40, RNaseP protein p40, RNase P subunit 1.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PEPQ_ECOSE
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVLDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMYSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: E13B_ARTSW
Sequence: MPHDRKNSSRRAWAALCAAVLAVSGALVGVAAPASAVPATIPLTITNDSGRGPIYLYVLGERDGVAGWADAGGTFHPWPGGVGPVPVPAPDASIAGPGPGQSVTIRLPKLSGRVYYSYGQKMTFQIVLDGRLVQPAVQNDSDPNRNILFNWTEYTLNDGGLWINSTQVDHWSAPYQVGVQRADGQVLSTGMLKPNGYEAFYTALESAGWGGLVQRAPDGSRLRALNPSHGIDVGKISSASIDSYVTEVWNSYRTRDMCVTPFSHEPGTQFRGRVDGDWFRFRNGSGQEVAAFKKPDASSVYGCHKDLQAPNDHVVGPIARTLCAALVRTTALTNPNQPDANSAGFYQDARTNVYAKLAHQQMANGKAYAFAFDDVGAHESLVHDGNPQAAYIKLDPFTGTATPIANGGSTEQPGTPGGLPAGTGALRIGSTLCLDVPWADPTDTNQVQLATCSGNAAQQWTRGTDGTVRALGKCLDVARSGTADGTAVWIYTCNGTGAQKWTYDSATKALRNPQSGKCLDAQGGAPLRDGQKVQLWTCNQTEAQRWTL
What is the function of this protein?
Lysis of cellular walls containing beta-1,3-glucans.  Implicated in the defense against fungal pathogens (By similarity).
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase, (1->3)-beta-glucan endohydrolase, (1->3)-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 64 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CYSC_ECO24
Sequence: MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: H2AZ_ASPTN
Sequence: MPGGKGKSIGGKAGSKDSAGKTQKSHSAKAGLQFPRGSVKRFLKNNTQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPRINRALLLKVEQKKKGKSDS
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received.  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins.  Required for the RNA polymerase II and spt15/TBP recruitment to the target genes.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: P6R3B_XENLA
Sequence: MFWKFDLHSSSHIDTLLERDEVTLKELMDEEDILQECKAQNRKLVEFLLKSECLEDLVTFITEEPPQDMDEKIRYKYPNLSCELLTSDVSQINDRLGEDETLLKRLYAFLLNDPPLNPLLASFFSKVLSILISRKPEQIVAFLKKKDDFVNLIIKHIGTSAIMDLLLRLLTCIEPPQLRQDVLNWLNEEKIIQRLVDIVHPSQDEDRHSNASQSLCEIIRLSRDQMLQVQNSSEPDPLLATLENKEILEQLLSNIFLKEKNESAIVSAIQILLTLLETRRPAFEGHIDLCPPGVNHSVFSVNKNVLAAIQERLPSFHQLLLDPPKTGVMKTTWGILDPPVGNTRLNVIRLIASLLQTNTHTINEELIELNTMGVILDMFFKYSWNNFLHTQVEICIALILASPGDSPEHSTISEENSAGDHVLLKHLFLKCHLIDRILEAWAMNEKRQSEGGQRYGYMGHLTRIVNCIVHSIEKGPNSVLAHQLVKDLPTDAQERWETFCTSSLSETNKRNTVDLVTTRHIHSSSDDEIEFKDPGFSQDSAIQQFGFNDEKFADQDDIGNVSFDRVSDINFSLNANESANIALFEACCKERIQQFDDGGSDEEDIWEEKNISYSQETQRRSSSGSTDSEESTDSEEEETIKQGFESSTVNHEDKMEVDANEASNWTANFDIPMETAHVANLDSDGSDVWSTEEPLSSKETDWASFSQLTSPINTKESVRSSSPVEMETSTEPVDPLSVNASAQTEVTVAMDAVSDGEEEGENADQMTETVMNGSMKETLSLTVDAKTETAVFKSEEGKLTTSHDSACKYGVVENSDTAMENPPSQPSSSSQEQRISEQIALDGASANGPV
What is the function of this protein?
Regulatory subunit of protein phosphatase 6 (PP6).  May function as a scaffolding PP6 subunit (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 6 regulatory subunit 3-B, SAPS domain family member 3-B.
What is the protein family that this protein belongs to?
Belongs to the SAPS family.
Protein: EXBB_XANCB
Sequence: MLQEFVIAAAAGGSNPSAALSQMGFEHLITEMTSSPGDFAVSWVVLITLIAMSAASWYWTVINIFRATRLKSAADRVTTAFWDAPNAQDAIRAMEEQPASEPFSKIALDAAQAAAHHQRAEGSTGGMGESLSRSEFVDRALRQAVTRESTKLQSGMTLLATVGATAPFVGLLGTVWGIYGALIKIGATGSASIDAVAGPVGEALIMTAIGLFVAIPAVFAFNFFSKVNSSVIAKFDTFAHDLHDFFATGSRVR
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.  Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
What are the official names of this protein?
Biopolymer transport protein ExbB.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL28_RIPO1
Sequence: MSRKCQLTGKKANNAYAVSHSHRRTKKLQEANLQWKRVWWPEGNRWVRLRLSTKAIKTLETKGLSVMAKEAGINLNKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RNZ_CHLMU
Sequence: MSYRGLTILGCSSQQPTRHRNHGAYLLRWNGEGLLFDPGEGTQRQFIYANIAPTVVSRIFISHFHGDHCLGLGSMLMRLNLDKVSHPIHCYYPASGKKYFDRLRYSTIYHETIKVVEHPISSEGIVEDFGNFRIEARQLDHLVDTLGWRITEPDTTKFISEKIKAAGLKGPIMQELINKGIIKVNNNIIRLEDVSYTRKGDSIAVVADSLPCQAIVDLAKNARILLCESTYLEEHAHLAKNHYHMTAKQAAEQAKRAEAQQLILTHFSARYNTTEQFVQEAGEIFPNVFAAEEFCSYEFPKNAN
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: DMTA2_MONAL
Sequence: MDLRPELPTASSASQVHPGAAAAAAAASIPVSMAGNLLRGPPLLLRAADKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPNYEVFGSVNNETNSDSSIPKYELFSKSQLSGSATPQQSVGKPASTESDSAPGISSPEGRHGGSGSENGDSESFISSPVSKPIKDGEETPGSVSSLGSDSGSETDKDDQEPSPSSAASRHMNAIDILTRVFPSHKRSVQELVLQGCGKDVVRAIEQILNNSGAQGPNKTGPEETWTAERMLQNAQQLPQSSASTTTPTRPMLPGAMTLSNRSAFSPLQPNAPHFGADPSTYPLGTPLGLNPLRLAYSAHSRGLAFMTPYSTTGLMPTLGFRPPMDYAFSDLIRDRTMLHKEQGYASGLYGPLVNNTPDKQ
What is the function of this protein?
May be involved in sexual development.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor A2, Doublesex- and mab-3-related transcription factor 5.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OR7A2_HUMAN
Sequence: MVKAGNETQISEFLLLGFSEKQELQPFLFGLFLSMYLVTVLGNLLIILAAISDSCLHTPMYFFLSNLSFVDICFASTMVPKMLVNIQTQSKVITYAGCITQMCFFVLFIVLDSLLLTVMAYDQFVAICHPLHYTVIMSPQLCGLLVLVSWIMSVLNSMLQSLVTLQLSFCTDLEIPHFFCELNEMIHLACSDTFVNNMVMHFAAVLLDGGPLVGILYSYCRIVSSIRAISSTQGKYKALSTCASHLSVVSIFYGTGLGVYLSSTMTQNLHSTAVASVMYTVVTPMLNPFIYSLRNKDIKGALTQFFRGKQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Putative olfactory receptor 7A2, Putative olfactory receptor 7A7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VDR_SAGOE
Sequence: MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSCCSDHYITSPDMMDSSSFSNLDLSEEDSDDPSLTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNPDYKYRISDVTKAGHNLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPESSMKLTPLVLEVFGNEIS
What is the function of this protein?
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity).  Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity).  The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity).  Plays a central role in calcium homeostasis (By similarity).
What are the official names of this protein?
Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes mainly to the nucleus. Translocated into the nucleus via both ligand-dependent and ligand- independent pathways; ligand-independent nuclear translocation is mediated by IPO4.
Protein: EHPR_ENTAG
Sequence: MTDLAGPTITPNLQLVYVSNVERSTDFYRFIFKKEPVFVTPRYVAFPSSGDALFAIWSGGEEPVAEIPRFSEIGIMLPTGEDVDKLFNEWTKQKSHQIIVIKEPYTDVFGRTFLISDPDGHIIRVCPLD
What is the function of this protein?
Required for resistance to the phenazine antibiotic D-alanylgriseoluteic acid (AGA), an antibiotic produced by E. agglomerans itself, and thus protects the bacterium against phenazine toxicity.  Probably binds AGA and acts as a chaperone that works in tandem with a membrane transporter for subsequent antibiotic secretion.
What are the official names of this protein?
Phenazine antibiotic resistance protein EhpR.
Protein: PCKA_PECAS
Sequence: MQINGITPQALAAYGIHDVRDIVYNPSYELLFKEERSPTLQGYERGIETQLGAVAVDTGIFTGRSPKDKYIVRDDVTRDTVWWSDQGKGKNDNHPLSQETWTHLKELVTTQLSGKRLFIIDAFCGANPDSRLSVRFVTEVAWQAHFVKNMFIRPSDEELEGFEPDFIVMNGAKCTNPNWQEQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMFSIMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRQLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPDIFGAIKRDALLENVTVLADGAVDFNDGSKTENTRVSYPIYHIHNIVKPVSKAGHATKVILLTADAFGVLPPVSRLTSDQTQYHFLSGFTAKLAGTERGVTEPTPTFSACFGAAFLMLHPTQYAEVLVKRMKASGAQAYLVNTGWNGSGKRISIKDTRGIIDAILNGSIDDAEMQTLPVFDLAIPTSLPGVNPDILDPRDTYASIEQWQEKADDLAQRFITNFDKYTDAPAGAALVKAGPKR
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF12_EUGMU
Sequence: MNIELIVQLGSLTLITIAGPLIVALLFLRQGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LPXA_CYACA
Sequence: MTNIHSTAIVHPAASLGRNVVVGPYSIIGSDVSIGDYTRIGPHVVITGKTVIGCNNQILSGCILGSVPQDLRYIDSELTGLYIGNNNLIRENVTVHRASGNGVTYIGNNNLIMVNCHVAHDCQIRNNIIISNSVSLAGHVIIDSCVIIGGHAGLHQFVHVGALSMIAAMSKIEKNVLPFVVVSGMPAITRTINLVGLKRYGISKTDINYIRLMLENLKVQPLAFDTYSIFKKFKSDNLLKRNVAVQYFSDFLFNSFRARGFIPFKVPKK
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell.  The target for the lipopolysaccharides produced in the chloroplast could either be the cell envelope of the eukaryote or the plastid membrane.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NQRE_RHOBA
Sequence: MVEQYLSVFLKAVFVENLALAFFLGMCTFLAVSKNVKTAIGLGIAVIAIETITVPANQLIYSLLLKKGALTWVNDYLISTDTYNFAEVDLTFLGFISYIGVIAAMVQILEMFLDRFMPSLYNALGIFLPLITVNCAILGASLFMEQREYPFGESVVFGFGCGVGWALAIMALAGIREKLKYSDVPPPLRGLGITFITVGLMSLAFMSFSGIQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SCMU_MYCTO
Sequence: MLTRPREIYLATAVSIGILLSLIAPLGPPLARADGTSQLAELVDAAAERLEVADPVAAFKWRAQLPIEDSGRVEQQLAKLGEDARSQHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNPASAPPEPPDLSASRSAIDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSLYQRALTTATQSYCQALPPA
What is the function of this protein?
Catalyzes the Claisen rearrangement of chorismate to prephenate.  May play some role in the pathogenicity.
What are the official names of this protein?
Secreted chorismate mutase, CM, *MtCM.
What are the subcellular locations of this protein?
Secreted.