PharMolix/UniProtQA huggingface dataset:
Protein: RPPH_SHESH
Sequence: MIDSDGFRANVGIIICNRFGQVMWARRFGQHSWQFPQGGVDEGETPEEAMFRELYEEVGLRPEHVQILTSTRSWLRYRLPKRLIRQDSKPVCIGQKQKWFLLQLKSNESAIDLNACGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPTALPFQTREHHHSRRGRRR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: CALT_CAVPO
Sequence: AFAPSKVDSDRPNCSRYVQHLYMCTKELDPVCGTDGHTYGNRSIF
What is the function of this protein?
Inhibits calcium transport into spermatozoa.
What are the official names of this protein?
Caltrin-like protein 1, Caltrin-like protein I.
What are the subcellular locations of this protein?
Secreted.
Protein: GATC_PROMP
Sequence: MKRISSDEVKKVAQLARLELNESEINQHAEQLEKILEYIKQLEKINTEDIPCTTRAIEVVNVLRKDEKKNYENSEEILDLAPSRENKFFKVPKIINE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CCD70_MOUSE
Sequence: MFPFKVSKWMGLACLRSLVLPSPSIRQKKLIHKLQEEKAFREEMKIFHEKIEDFREEIWEFRGKIRAFRGQILGFWEEERPFWEEEKIFWKEEKTFWEMEKSFREEEKTFWKKYRTFWKEDKAFWREDNALWERDRNLLQEDKALWEEEKALWVEERALLAEEKALWEDKKSLWEEENALWEEEKALWVEGGGFHLLGEQRHQNGPYNANEEPQSTSFPRGRA
What are the official names of this protein?
Coiled-coil domain-containing protein 70.
Protein: THI4_NEUCR
Sequence: MSPSVLEPQSVPTLVNVGLKAVGRNDAPVERDARGLSKPLLELMPTLGTDAFTFSPIRESTVSRAMTRRYFADLDAHAETDIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAWLGGQLFSAMVMRKPADVFLDEVGVPYEDEGDYVVVKHAALFTSTVLSKVLQRPNVKLFNATTVEDLITRKHHAESSSSSDDGEAEDEAKVRIAGVVTNWTLVSMHHDDQSCMDPNTINAPVIISTTGHDGPFGAFSVKRLVSMKQMERLNGMRGLDMQSAEDAIVNNTREIVPGLIVGGMELSEIDGANRMGPTFGAMALSGVKAAHEAIRVFDLRKAQNDKC
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, 37 kDa NcCyP41-binding protein, CyPBP37, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACP_SALHS
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_DICTD
Sequence: MQFKILVVGKLRNEFIKAGVNEYLKRLLPFINIKIEFLPSFSELPEKMALLKEEEIILKNIKNNEFIIILDKNGEKLSSEEFSNKLFKLTTLNPQITFVIGGIYGVSENIKKSSKFLLSLSPMTFTHEFALLILLEQIYRAFKINRNEPYHY
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_STRPM
Sequence: MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDREGYAKSVTAELENHPLIEVIRDEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGFYFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHDALTNAEEAPLNAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLTETFQSRNNPNLFFAGQMTGVEGYVESAASGLVAGTNAARLFKREEALVFPQTTAIGSLPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2054_AQUAE
Sequence: MRFFLTFLLFLFTLFSLFVYDFLRKKNFYLDLDLDIRTRTVKELILNLERFFGLNLYLNFKDIKFEKIIKIEKGKVVVVSFKKRKKKKKFLLKNIPIREIPINLKIGHLDVWTGNEGGVNRVIVKDASLINNELEGEFLYTNLRSFTLNGSIKAKIQRDTLTLKDLLLDSEYFSAKTKGEIKRNTGEILAEVEIKEIRKENFTLSGTKINAKGTINLPVLDINAKAFVKDLIVRNKNYGSIEGIVKGNYELFDKLFLKGEAVNPEGTKIKFTYDVIPEGLLTFSFENLVVDKNTLGINREIRGEFHGNGKVDFKKMFVKVNAFTENLEVIDKKFKGDVLFSYNFSGNGSLNFEFKNSGYAKGNLIINKNKLEGEFSFNDFPVVFQDFNAYLSGEGKFKKGKIFEMEAKIFANNGQFRDFSLQRISSDVKIRDKEIEALVYYGNSFGFVKGKFDNLKGFIQLNNFSLEGKEKSIKISHGSIEFSIQGKSINSKGKLGDLALNLSNIYAKTELEFNFNKKNEKITLEGNGILNVRFKEKSVLENFKYSLLLLDNNLRIFGASKDSILRVVYYISGRSGEFYGKIDKKEFGISLNGEIKNKDVKANFEAFYALLREKIKIKGKIETKEDQVKISLFPTQLRGKRFNYRFNGLNVFLEKENLSVEFKGLDVSLLDKKLLSISPSKGVGTTKNFSFEPVKITGVLNGVLNIAYKGNLYLKSSGTLNLTLLSKHIGSLMKSQMFGKLDYEFVFDGNELKFLARNDEPVRINSLYFYEPFGSAMNLELRKDFFAFALTGWFREGFLNAYAISKNFRDFEVEFVYKNLPVKLKDGIRARIEADGKGKVVVKNFKEIFLTLDTLLDGYVKVKKLPEKKEEEKKTLPVEITLDINFKTENGLIVKLPEGRVYTALNGRIYGKLPEPYYEIDVVLKSGRLEYFGRKFFVKRSTVKLLKEKDKELTEFDFYLNTVSDGYKIFLLVHGTPENPSVYYFSEPPLSREQILFKLISGGVNEGILPVGTVLANELKALGYVKGTIERLFDVNVEIGIKTSSTGEVGALVKLKKKLGSYFSLYYQTASTKDKKDTFWGAEVRSPGSLDLGFSFNVYSDNTREYKLRYVREFDF
What are the official names of this protein?
Uncharacterized protein aq_2054.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACYP_ALIF1
Sequence: MSQKSYLFNVKGKVQRVGFRFHTAHNALKLGLTGYARNQEDGSVEVLVCGSKDKINQFLEWLQVGPQLARVDSIKQEETQWQELTDFKMY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: NCLN_CHICK
Sequence: MLEEAGEVLESVLKASCLPLSFLLFVPAVLLLLGPPPAAEAAHESTVYRMQQYELGGQPYGTRSAVLNTEARTVEADVLSRRCVMMRLVDFSYEQYQKALRQSAGAVVIILPRSISSVPQDVVKQFMEIEPEMLAMETIVPVYFAVEDDELLSIYEQTRAASASQGSASAAEVLLHTATANGFQMVTSGAQSKAIHDWLIPSVEGRLTGLGGEDLPTVVIVAHYDSFGVAPWLSHGADSNGSGVSVLLELARLFSRLYTYRRTHAGYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTLGRGNSLHLHVSKPPKEGTLQHAFLRELEMVVASQFPEVKFSMVHKKINLAEDILAWEHERFAIRRLPAFTISHLESHRDSLRNSIMDRRSQVDTKALTQEYQDHCGGFDEGHLQPNREGSTCRSADLHGSDADPGGAARISDGLAEQSAQAAQLIDKDSTFLSTLEYYMGRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAIFDLLLAVCIAAYLGVAYVAVQNFGLLYRMIQRLSLKTKQQ
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity).  May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NOMO (By similarity).
What are the official names of this protein?
BOS complex subunit NCLN, Nicalin, Nicastrin-like protein.
What is the protein family that this protein belongs to?
Belongs to the nicastrin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PRM1_EMENI
Sequence: MIFSRSARSIFPLLPPYGAHDPQGGRAVPLQPDDITPYMGLRARLSQIWMNRWTILLLLVLVRVLIAIASLNTNMDSARREALSACTSVESMGSAMASMPHYSARGINELTASGVETAVSALKTMLTLVVSGVEELIVFFIKMMYQTYLCLITMAVRGTVDVGVGLLKDASDFLNSTIKSIGEGISDATQTFEDGLNKFVDGINIVGSVFGGDEVPDLDLSSFIEDLENAQLPSSIDDGLDKLNDSVPTFDEVSEFVENIIRTPFDEVKKLINESMGTFTFDRDTLPVPAKKQLSFCKGSDGIDSFFNNVSDIAETAKKVFIAVLVIAAVLVCFPMAWQEIRRWRAQKERSQLVRKEAHDPLDVVYIVSRPYSAAAGIKAASRFSNSRRQILVRWVIAYATSPSALFVLSLAIAGLFACLCQYLLLRAVEEAVPELSAEVGAFADKVVASLDNTSAEWALSANSAIGDINTELNDKVFGWVNSTTTGVNDTLNTFVDKTTGVLNDTFGGTLLYDPLKDVFDCLIGLKIAGIQRGLTWVHDNAHIDFPELSNDTFSRGAAESLSDDNSSESFLSDAGASTSNKITEVVFRVTSAIESGIATEALISGAILLIWFLNLLFGLIRALSLFRSHDRNRGDGGPGPAANLDPNDGFSDVPLTAIPNPHTTAHSAADSQSRSQPVPEYEPPSRNFASAGPPAAVTAQTTYEDEKLGFAGQRRNALKVSVIDARASSYPEFGDEKR
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein prm1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NQRE_PSEMY
Sequence: MEHYISLFVRAVFVENMALAFFLGMCTFIAISKKVETAIGLGVAVIVVLGITMPVNNLIYANILKDGALAWAGLPEVDLSFLGLLTFIGVIAALVQILEMTLDKYVPSLYNALGVFLPLITVNCAIMGGSLFMVERDYNLAESTVYGIGAGVSWALAIAALAGIREKLKYSDVPAGLQGLGITFITIGLMSLGFMSFSGVQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CABP1_BOVIN
Sequence: MGNCVKSPLRNLSRKMRQEETSYTVVQTSEEGLAASGELPGPLLMLAQNCAVMHNLLGPACIFLRKGFAENRQPDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR
What is the function of this protein?
Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs).  Inhibits agonist-induced intracellular calcium signaling.  Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels.  Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function.  Suppresses the calcium-dependent inactivation of CACNA1D.  Inhibits TRPC5 channels.  Prevents NMDA receptor-induced cellular degeneration.  Required for the normal transfer of light signals through the retina.
What are the official names of this protein?
Calcium-binding protein 1, CaBP1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell membrane; Lipid- anchor; Cytoplasmic side. Golgi apparatus. Postsynaptic density.
Protein: SYK_DICNV
Sequence: MSHNEKIQDENKLIAERRQKLQKIRDTQKIAFPNDARPTHKAAQLHRDFDHGDEAALSQAGTVAIAGRMMGKRVMGKASFVHVQDGSGEQIQLYVSSDALTEEVYEEFKTWDVGDIIFASGSLFRTKTGELTVQTNAIRLLTKSLRPLPDKFHGLTDQEIRYRQRYVDLMVNAQSRDVFKARSKIISYIRHFFEARDFLEVETPMMHPIPGGAAAKPFITHHNALDMPLYLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSARHNPEFTMLEFYQAYADYNDLMDLSEVLFQGLAQTILGTTKFDYQGTEIDFSQFRRLPMRDAVCQYVPEAANILEDAPKMVQLLKEKFHIDAGNESDCGKLMTMIFEEGVEHLLIQPTFVIEYPAVVSPLSRRNDENPDITDRFELFIGGREIANGFSELNDAEDQAERFKEQAAAFEAGDEEAMHYDGDFVRALEYGLPPTAGQGIGIDRLVMLLTNAPSIRDVLLFPHMRPE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_ACTSZ
Sequence: MALERTLSIIKPDAVERNLVGKILSRFEENGFQIVAMKMLRLNQAQAEGFYAEHQGKPFFDGLVEYMTSAPVVVSVLEKDNAVKDYRTLIGATDPQQAAEGTIRKDFAESRRRNSVHGSDSEESAVREIAYFFVESEICPR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLIC1_RABIT
Sequence: MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVHKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGVDIFAKFSAYIKNSNPALNDNLEKGLLKALKILDNYLTSPLPEEVDETSAEDEGISQRKFLDGNELTLADCNLLPKLHIVQVVCKKNRGFTIPEVFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK
What is the function of this protein?
Can insert into membranes and form chloride ion channels.  Channel activity depends on the pH.  Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions (By similarity).
What are the official names of this protein?
Chloride intracellular channel protein 1.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Nucleus. Nucleus membrane; Single-pass membrane protein. Cytoplasm. Cell membrane; Single-pass membrane protein. Note=Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).
Protein: NUOD2_HERA2
Sequence: MLKTEELQINIGPQHPSTHGVFRMLVTVDGETLVDLKPVFGYLHRNHEQLGEVNTYLQNMPFTDRLDYFNSMVNNHAYARAVETLAGVEVPERAQYIRVIMDELSRILNHATAMGFMLGDMGAWQTALLWGMREREKILDMFEYVSGARMMCNYCRFGGVVRDIDDWFITELKKLMQGLPHYFDDFEGLLLNSEILLARARNIGVLPKELALAYSVTGPVLRGSGVAYDIRKAEPYAVYDRFKFKVPVGTVGDVYDRFLVRIAEMRESYKILEQAIEQLPDATGGFINPKVKQQSLKAPAGEAYARVESPKGELGFYLVSDGSGSAYRYKVRAPSFINLSSLADMCKGYSIADVVVILGSIDIVMGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BOP3_YEAST
Sequence: MSTFNSYSQPKESNDNSHNNVNKSKSLLDIIFGTNVSEWAFSENALMKAMDLKIEQEKTKQQYYKLENLNRSIELFKLASSSGLPINQIHKLFNTDHGVPASSPMKAGGNQPHNNTEGTQSSENLPRLNGSMKSLKPLNMNTVSPTPMSRQPSPYKFPASSSTGGISHSTVTNVQRRANSPARIGASAVAALNDNISIKEEDVARRIPSGTKSQESPLNKKPTSLHSRNLSLPIGKFTNPNIPSTMTSILSFNRDQQQPLSQPLPPPPQQQQDLHTHNLHTIPRKPGMVQKKHRRARSTSSFGVIDLSIIDEAKEKQVQRSPSPIHSNVSVALTSHDKPIESNMKEQPNMLQSVREGRQVHDDLDDRTCSESSSRNESPVRTITKDNSVGKILNST
What is the function of this protein?
Involved in resistance to methylmercury.  Overexpression suppresses a PAM1-SLV3 double null mutation.
What are the official names of this protein?
Protein BOP3, Bypass of PAM1 protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RNPA_SHESA
Sequence: MTSYTFTRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNSEQHPRLGLTVAKRYVKRANQRNRIKRVIRDSFRLNQHDIPHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: NDK_CHLMU
Sequence: MEQTLSIIKPDSVGKAHIGEIVSIFEKAGLRIAAMKMVHLSVKEAEGFYAVHKERPFFQELVDFMISGPVVVMVLQGENAVARNRELMGATNPKEAAEGSIRALFGESIGVNAVHGSDSLENAAIEVSYFFAKTEIVNALA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCDB_ECO57
Sequence: MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system, functioning in plasmid maintainence.  Responsible for the post-segregational killing (PSK) of plasmid-free cells, also referred to as a plasmid addiction system.  Half-life of over 2 hours.  Interferes with the activity of DNA gyrase, inducing it to form a covalent GyrA-DNA complex that cannot be resolved, thus promoting breakage of plasmid and chromosomal DNA.  Toxicity is inhibited by labile antitoxin CcdA, which blocks the activity of CcdB; CcdA also removes bound CcdB protein from the CcdB-GyrA complex by forming a CcdA-CcdB complex, a process termed rejuvenation.  Functions as a transcriptional corepressor for the ccdAB operon, repression also requires CcdA (By similarity).
What are the official names of this protein?
Toxin CcdB, Cytotoxic protein CcdB, LynB, Protein G, Protein LetD.
What is the protein family that this protein belongs to?
Belongs to the CcdB toxin family.
Protein: LSD2_SCHPO
Sequence: MPLGRSSWICCAKYFVNTKSRFNEILPPRFTLIVSFYSMNTSENDPDGHYDFPEMTEHHSDRASSYANANNVNSTQPQLVSSEQALLAILGGGLQSITPNSVNQNAYSRSTYRTDGGLNSQPVSSLNNQWGNYNPAFLPSRYDSSFHPYTISQAANQPFPQHLLGNSNAGVAQQSGMRTIGLPPTVGSSFPQQKSSTYENFFDANSPSSQQFPSTYPSRSQNPLSSSGDGSTAIHAGPIQHQNSNAFSNYPYPLDASHLSSQQLLSMYRDQVSHGVTPSTFRNHESFMPTQLVSATELSKSVDNAVLPIPPTTAPAVVSPPASSFPLMSSAATSGNISSPALFDSELGARPEGSVAIEPSRVLLQWSSQSSSHTIPSAGASIPTSSLKSFFEHAAEAARKCNLDPRALESFEQHMLSDRLHDPVVLFHYFQIRNSICWLWIKNPTHAISRVEAQGVCVDRCLFQLASLAYEFLVRYGYINYGCLSFDSSFTNETNTGTTSSSASKQKTIAVVGAGLTGLICARQLTGLFSQYSSSFLSKNELPPKVIILEAKERTGGRIYSRALPVSHTSATQINHHTSNSNSISSNSTSLNPKDVTDPSHIPSAIDLGFQFLFSPMDDILLNLLNKQLGIEVTEMTGSDLVYDETDTKVLDMVEVKKLNILWEKLLEYVSVCFFINVEESVRISWISQFQLFIDEMFPDHLSKSLSLNASHEFSFKKTMLILIDEVSSYAKLGNSQKKFLIWCFKVAELDDTLYPLNTVDTDFSKDILIPKVARRGLSQLPWALQSYPSPLNIHYEKFVSKVTIENDKCTLDCKDNSSYEVDQVVIACSPSHFSSNIEFSPGLPNFVTENIKSIDFKPGKKVILRYAAAFWRKNIRSFGIIPKSLSQEMNNDENDGKSCFVLRIWNMLPETGVPILVADINPQMTSSSSNETSHLIQELHSLIVDHFQNDSNSSADLLDAWVTNWSRNGVYDGLNSYPNFANDKQQYEKRFRQSQLSYNLGRLHIAGDYIFSCVGCRTLQRSFLSGLSVCTGIIDSLAPISLTIPIIGETSRKELDQFLRNSKVNNFDPNAEAQRHLSYQARYRLKKQERLDEHKEEQEQLVTELLGYLPEPPSKPNANPFLLYQKMQWHVCRALADEDKRRLTGDSTAKATINETRAKLGKTWRQLDDLGKKPWIDEIAAQREAYAGKILRYQRLTKEYEMRAEQIRNDYAAKCQDEPIPDDEARLFMQAQREEEQRKQTQDDNISKSREASDEEYHDDGSSDSGYNGTRY
What is the function of this protein?
Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.  Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.  Has a role in regulating heterochromatin propagation and euchromatic transcription.  Also has a gene activating role.
What are the official names of this protein?
Lysine-specific histone demethylase 2.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SHAKB_AEDAE
Sequence: MLDIFRGLKNLVKISHVNTDSPVFRLHYSITVMILMAFSLIVTTKQYVGNPIDCVHTKDIPEEVLNTYCWIHSTYALKSLFLKKVGSEVPYPGVGNSDGKNIDKKIYKYYQWVCFCLFFQAILFYTPRWLWKSWEGGKIHALMMDLDIGICSEIEKKQKKKLLLDYLWDNLRYHNWWAYRYYICEFLSLVNVIGQMFLMNRFFDGEFMTFGLDVITHMEADQEDRMDPMIYIFPRMTKCTFYKYGVSGEVERHDAICILPLNVVNEKIYIFLWFWFIILTILTTLTIFYRIIIIFSPRMRVYLLRLRFRLVRRDAIEIIVRRSKMGDWFLLYRLGENLDSIIFRDVMQDLANRLHNNQHHRVPGMKGEIQDA
What is the function of this protein?
Structural component of the gap junctions at electrical synapses in distal and mid-depth levels in the lamina.
What are the official names of this protein?
Innexin shaking-B.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: AROE_PYRFU
Sequence: MINGETKIYGIIGNPVKHSLSPIMHNALFKKFGINAIYVPFEVKKDLKNAINGVKALDIQGVNVTMPYKEEVIKFLDELSEDSQNIGSVNTVVNLEGKLVGYTTDGIGARRALERFTQVDGANILILGAGGAGKAIAYELSKVANVVVLNRTIEKAKRLEKFGIVGDSLEALPYYVEWADILINATSVGMNEEKSLVPKNLLRPGLVVMDIVYKPLNTLLLRYAQEKGCIAIDGLWMLVYQGAESFRLWTGEEGDVELMRRVALAWLRERK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PLSX_CAUVC
Sequence: MSQSLVISVDAMGGDHGPSIVVPGIAQALQALPGVRFLLHGDGAAIEAELAKHPGAKAVSEVRHCDKAIGMDEKPAQAMRRGKGSSMWNAVEAVRENEAQACVSAGNTGALMAISKLILRMGAELERPAIVANWPTMKGVTTVLDVGANVESDASQLVEFAIMGAAFHHAVHGSKRPTVGLLNVGSEDQKGHEEVREAHAILRETTLDFDYHGFVEGNDIAYGTVDVVVTDGFTGNVALKTAEGLARFFSNEIKSTLTSGPLAMLGALIASGALKKMRHRLDPSRVNGAPLLGLNGIVVKSHGGADANGFASAIRVATNLARSDFRAEIDRNLKRLTATAAAIKSGDGQGPGEDAQGVAE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.