PharMolix/UniProtQA huggingface dataset:
Protein: SEPT1_BOVIN
Sequence: MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQIPEASARLTQTLTIERRGVEIEEGGIKVKLTVVDTPGFGDSVDCSDCWLPVVRFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPKETQALKQKIREQLKEEEINIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGPRPVRGRHYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQLSQAQGEQSDAL
What is the function of this protein?
Filament-forming cytoskeletal GTPase (By similarity).  May play a role in cytokinesis (Potential).
What are the official names of this protein?
Septin-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis (By similarity).
Protein: MSBA_LEGPA
Sequence: MKNNLPIKSRLLYKRLLSYVKPFWPVLLLGVLANILYSGIDAGFTYMTKLFLDKSFITIDLDFVKQIPLIVLIGITLRGLVSSLGSYCMTWVARSVVKVLRQTVFSHIIHLPADYYDEATSGQLLSKILYDVEQVAQVSADALTDFIQNICLVIGLLTVMMVICWQLSLMFLLTIPFVGIIVNYTNKRVRRISHKVQKTMGEVTEIASEAIEGYRVVRIFGGERYEITKFNKATEYSRKNDMKVAISKAINVSGVQLVIAIGIAMIIMAAIHLSTVITISAGSFLAIIAAMLQLIKPMKTLTTLNATIQRGLAGAESVFNLLDLPLERNNGLILKEKVRGEIEFKHVYHAYRQSQNILHDVNFVIEAGTSVALVGHSGSGKTTIASLLPRFYELSQGMITLDGMPIQQLSLESLRKQISLVSQNVTLFNDTLANNIAYGRFDASREQIITAAKLAYADEFIKQLPDGYDTRVGENGVLLSGGQRQRIAIARAILKDAPILILDEATSALDSESEHYIQAALEQVMKGRTTLIIAHRLSTIKHAHKIIVLQHGRIVEQGSHQELLDMDGHYAQLYKVQQFGRINEEVVV
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRED_BACSU
Sequence: MKRFLLPFVMMLVFSAESIFTDLVHFPFVTDDQVLAPRFLMLVLIFMSAFINQKHAMIYGFIFGFLYDMNYTSLLGVYMFGFAGLCYLASKAFKVLHTNAFVVILIAVLAVCLLEFYVFGIQSLIHKDIMTFNGFVLDRFIPTILLNIAAALILVLPFRLFFMSLKKELRDE
What is the function of this protein?
Involved in formation of the rod shape of the cell.  May also contribute to regulation of formation of penicillin-binding proteins (By similarity).
What are the official names of this protein?
Rod shape-determining protein MreD.
What is the protein family that this protein belongs to?
Belongs to the MreD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILVD_AGRVS
Sequence: MPAYRSRTTTHGRNMAGARGLWRATGMKDGDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPTVFVSGGPMEAGKVVMHGKKVALDLVDAMVAAADDKISDEDVATIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHSDRKRLFVEAGHLIVDITRRYYEQDDENVLPRNIASKQAFENAMALDIAMGGSTNTVLHILAAAYEGEIDFNLDDIDQLSRRVPCLSKVAPAKQDVHMEDVHRAGGIMRILGELDRGGLINRDCPTVHAPTLGDAIDRWDITRTNSETVREFFRAAPGGVPTQVAFSQSSRWDELDMDRENGVIRSVEKPFSKDGGLAVLKGNIALDGCIVKTAGVDESILKFTGPAKVYESQDSAVKAILSNEVVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKVCALITDGRFSGGTSGLSIGHVSPEAANGGTIGLVRNGDTIAIDIPNRTIELMLSEGELAARRVSQDAAGWKPAEHRKRKVTTALKAYAAFATSADLGAVRKLPE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GRPE_SHESR
Sequence: MSNESIKAEQDLIQEGVESEVSTEEASLIDELTQANFRIEELEQLLADALAKVEEQKDSVIRAAAEVDNIRRRAAMDVEKANKFALEKFANELLPVLDNMERALQGTNPQDETTKAIYEGVELTQKSFLTAVAKFGVKPIDPQGQAFNPDQHQAIGMQPSAEYPANTVMLVMQKGYELNSRLLRPAMVMVSQGGPSQEINIEA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRR14_HUMAN
Sequence: MDLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEEIYTNKNYQSPTTRRTFETIFEEPRERNGTLIFTSSRKLRRAVEFRDSSLPRSRRPSRGVRAAGGRTVPPNVAPSPDVGPLLQQRLEELDALLLEEETVDREQPHWT
What is the function of this protein?
Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha (PubMed:24209742).  Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit (PubMed:24209742).  Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha (PubMed:25906157).  Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 (PubMed:27041574).
What are the official names of this protein?
Proline-rich protein 14.
Protein: TUSB_SALTY
Sequence: MLHTLPHCASSVDFPALLRLLKEGDALLLLQDGVTVAIEGNRFLESLRDAPITVYALKEDIDARGLGGQISDSVVRVDYTEFVRLTVKYANQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUS4_MOUSE
Sequence: MVTMEELREMDCSVLKRLMNRDENGGGGSAGGNGSGSHGALGLLSGGKCLLLDCRPFLAHSAGYIRGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSTNESLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLTTSCAAEAASPSGPLRERGKATPTPTSQFVFSFPVSVGVHAAPSNLPYLHSPITTSPSC
What is the function of this protein?
Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
What are the official names of this protein?
Dual specificity protein phosphatase 4.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPE_ENTFA
Sequence: MEIIERAPAKINLGLDVLHKRVDGYHEVESIFASVDLADHLTFENLEEDIIRIETDSSFLPVDRRNHVYQAVDLLKRTYNIHKGIKIYIEKRIPVAAGLAGGSSDCAAALRGLNKLWNLGLTMDELCEIGSQIGMDVPYCLRGGTAFANGRGEKIEALPTMPQCWIVLVKPRISVSTSTVFNDLAVDELHHPDIAGLRIAIENGDYTGMTQTVGNALESVTIARHPIVQQIKDRMLKYGADAALMSGSGPTVFALCEKKTRAQRIYNGLKGFCEEVYLVRTLK
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SYI_GEOKA
Sequence: MDYKETLLMPKTDFPMRGNLPKREPEMQKKWEEMDIYRKVQERTKGRPLFVLHDGPPYANGDIHMGHALNKILKDIIVRYKSMSGYCAPYVPGWDTHGLPIETALAKQGVDRKSMSVAEFRKRCEQYAYEQIDNQRRQFKRLGVRGDWDNPYITLKPEYEAQQIKVFGEMAKKGLIYKGLKPVYWSPSSESALAEAEIEYKDKRSPSIYVAFPVKNGKGVLEGDERIVIWTTTPWTIPANLAIAVHPDLDYHVVDVSGKRYVVAAALAESVAKEIGWDAWSVVKTVKGKELEYVVARHPFYERDSLVVCGEHVTTDAGTGCVHTAPGHGEDDFLVGQKYGLPVLCPVDERGYMTEEAPGFAGMFYEDANKAITQKLEEVGALLKLGFITHSYPHDWRTKQPTIFRATTQWFASIDKIRNELLQAIKETKWIPEWGEIRIHNMVRDRGDWCISRQRAWGVPIPVFYGENGEPIITDETIEHVSNLFRQYGSNVWFEREAKDLLPEGFTHPSSPNGIFTKETDIMDVWFDSGSSHQAVLVERDDLVRPADLYLEGSDQYRGWFNSSLSTAVAVTGKAPYKGVLSHGFVLDGEGRKMSKSLGNVVVPAKVMEQFGADILRLWVASVDYQADVRISDHILKQVSEVYRKIRNTFRFMLGNLFDFDPNQNAVPIGELGEVDRYMLAKLNKLIAKVKKAYDSYDFAAVYHEMNHFCTVELSAFYLDMAKDILYIEAADSRARRAVQTVLYETVVALAKLIAPILPHTADEVWEHIPNRRENVESVQLTDMPEPIAIDGEEALLAKWDAFMDVRDDIFKALENARNEKVIGKSLTASVIVYPKDEARKLLASLDADLRQLLIVSAFSIADEPYDAAPAEAERLDHVAVIVRPAEGETCERCWTVTKEVGADPSHPTLCPRCAHIVNEHYSA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR2_YEAST
Sequence: MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.  RNR2 provides the diiron-tyrosyl radical center.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain 1, Ribonucleotide reductase R2 subunit 1, Ribonucleotide reductase small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Nucleus. Note=Found predominantly in the nucleus under normal growth conditions and is redistributed to the cytoplasm in damaged cells in a DNA replication and damage checkpoint-dependent manner. Nuclear localization is mediated by DIF1.
Protein: YCF12_EUGSA
Sequence: MNIELIVQLTSLALITLAGPLIVALLFLKQGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SSK_BOMMO
Sequence: MVSVQTIATIVVKTFKIVLNIIILVLYRTGYNGEFLGVGGTWNLNEEKNPDAEIVASGVIVGYLIYTLVQIVTFLFGTTEHKRALSEIVMNFVGVFLWIAVGAVALHYWGGYQGEHQFQFVFAEKQVGLAVGALCVINGAIYLLDTALSVIHFTKEM
What is the function of this protein?
Required for assembly of smooth septate junctions (sSJs).  May be important for barrier function of the midgut epithelium.
What are the official names of this protein?
Protein snakeskin.
What are the subcellular locations of this protein?
Apicolateral cell membrane; Multi-pass membrane protein. Cell junction, septate junction. Note=Specific to smooth septate junctions.
Protein: APOC4_DICSS
Sequence: MLLPGRRPWALHSFCFYVLVLAWVVACQQEVPTGSPSPPPGRASGLWGLVRGKVKEFMEPLVTKTRERWRWFWGPSAFQGFMQTYYDDHLRDLRPRAQAWLRSSKESLLNKAYNMCPQLLCRDGDQG
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAA_EMIHU
Sequence: MKVGSKELEASKVRVIVDKDPVATSFEKWAQPGHFSRTLAKGPKTTTWIWNLHADAHDFDSQTSSLEDISRKIFSAHFGQLAIIFLWVSQAYFHGARFSNYSAWLLNPTSIKPSAQVVWPVVGQEILNGDVGGGFSGVQITSGVFQMWRASGITNETELYWTAMGGLMMSALMVFAGWFHYHKAAPKLEWFQNVESMMNHHLAGLLGLGCLSWSGHQIHISLPINKLLDAGVAPQEIPLPHELLFNQDLMAQLYPSFKKGLLPFFTLNWGEYSDFLTFKGGLNPITGSLWLSDTAHHHLALAVLFIFAGHMYRTNWGIGHSMKEILEAHKGPLTGEGHKGLYEILTTSWHAQLAINLAMMGSLSIIVAHHMYAMPPYPYIAVDYPTQLSLFTHHMWIGGFCVCGAAAHGAIFMVRDYSPVQSYNNLLDRVLRHRDAIISHLNWVCIFLGTHSFGLYIHNDTMRALGRPQDMFSDKAIQLQPIFAKWVQSLHTLAPGNTAPNSLATASYAFGGDVVAVNGKIAMMPIQLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHIFLGLFWMYNCISVVIFHFSWKMQSDVWGTISEKGKITHITGGNFANSALTINGWLRDFLWSQASQVIQSYGSALSAYGIIFLGAHFIWAFSLMFLFSGRGYWQELIESVVWAHNKLKLAPAIQPRALSITQGRAVGLAHYLLGGIGTTWSFFLARIISVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YCF2_CAPBU
Sequence: MKGHQFKSWIFELREIVREIKNSHYFLDSWTQFNSVGSFIHIFFHQERFRKLLDPRIFSILLLRNSQGSTSNRYFSIKGVVLFVVAALLYRINNRNMVESKNLYLKGLLPIPMNSIGPRNDTSEESFGSCNINRLVVSLLFLTKGKKISESCFRDPKESTWVLPITQKCIMPESNWSSRWWRNWIGKKRDFCCKISNETVAGIDISFKEKDIKYLEFLFVYYMDDPIRKGHDWELFDRLSPSKRRNIINLNSGQLFEILVKDWICYLMFAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFHQDLFVSWGKNPHESDFFRKISRENWIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSSFVQVTDSSQLNGSSDQFIDPFDSISNEDSEYHTLINQREIQQLKERSILLDPSFIQTEGREIESDRFPKYLSDYSSMPRLFTEREKRMIIHSLPEESEEFLGNPTRAIRSFFSDRWSELHLGSNPTERSTRDQKLLKKEQDVSFVPSRRSENKEIVNIFKIITYLQNTVSIHPISSDLGCDMVPKDELDMDSSNKISFLNKNPFFDLFHLFHERKRGGYTLRHESEERFQEMADLFTLSITEPDLVYHKGFAFSIDSYGLDQRQFLKEVFNFRDESKKKSLLVLPPIFYEENESFYRRIRKNWVRISCGNYLEDPKRVVFASNNIVEAVNQYRLIRNMIQIQFQYSPYGYIRNVLNRFFLMKRPDRNFEYGIQRDLIGNDTLNHRTIMKDTINQHLSNLKKSQKKWFDPLIFLSQTERSINRDPNAYRYKWSNGSKNFQEHLEHFVSERKSRFQVVFDQLCINQYSIDWSEVIDKKDLSKSLRFFLSKLLRFFLSKLLLFLSKLLLFLSNSLPFFFVSFENIPIHRSEIHIYELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHNTSQKSKFLINGGTISPFLFNKIPKWMIDSFHTRKNRRKSFDNTDSYFSIVSHDQDNWLNPAKPFQRSSLISSFSKANRLRFLNNPHHFCFYCNKRFPFYVEKARLNNSDFTYGQFLTILFIHNKIFSSCGGKKKHAFLERDTISPSSIESQVSNIFISNDFPQSGDERYNLYKSFHFPIRSDPLVRRAIYSIADISGTPLIEGQRVNFERTYCQTLSDMNLSDSEEKSLHQYLNFNSNMGLIHTPCSEKYLQRKKRSLCLKKCVDKGQMDRPFQRDSAFSTLSKWNLFQTYMPWFFTSTGYKYLNLIFLDTFSDLLRILSSSQKFVSIFHDIMHGVDISWRILQKKLCLPQRNLISEISSKSLHNLLLSEEMIHRNNESSLISTHLRSPNVREVLYSILFLLLVAGYIVRTHLLFVSRAYSELQTEFEKIKSLMIPSYMIELRKLLDRYPTSELNSFWLKNLFLVALEQLGDCLEEIRGSGGNMLWGGDPAYGVKSIRSKKKDLKINFIDIIDLISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVSGDWIDDKIESWVANSDSIDDKEREFLVQFSTLRAEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGTIYLRYLVDIHKKYLMNYEFNTSCLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSPSRSILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFFIDDIDIDDSDDIDASNDIDRELDTELELLTMMNALTMDMMSEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESSYLALGLLVNSLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLENKMFHTNGFESITMGSSARDLVALTNEALSISITQKKSIIDTNTIRSALHSQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLISNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKKFTILLYLLSCSAGSVAQDLWSLPVPDEKNRITSYGFIENDSDLVHGLLEVQGALVGSSRTEKDCSQFDNDRVTLLFRSEPRDPLYMMQDGSCSIVDQRFLYEKYESEFEEGEGEGVLDPQQIEEDLFNHIVWAPRIWRPRGFLFDCIERPNELGFPYLAGSFRGKRIIYDEKYELQENDSEFLQSGTMQYQRRDRFSKEQGFFRISQFIWDPADPLFFLFKDQPFVSVFSHREFFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLIQRQRWLRTNSSLSNGFFRSNTRSESYQYLSNLFLSNGTLLDRMTKTLLKKRWLFSDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RNPH_FRAP2
Sequence: MRPSGRNNDQLRTLKVTHNFTKHAEGSVLIEFGDTKVLCTASVVAGVPRFKKDSGEGWLTAEYGMLPRSTHTRMDREAARGKQSGRTQEIQRLIGRALRASVDLTKIGENTIKVDCDVIQADGGTRTASITGASLAIRDAIDYMKQNGMLDEQTSPLMSQVAAISVGIFNNEPVLDLDYDEDSNAETDMNVVMNSNGGMIEIQGTAEGKDFSEEEFAKMLGLAKKGIKEIFESIF
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: MGSA_BACSU
Sequence: MKIALIAHDKKKQDMVQFTTAYRDILKNHDLYATGTTGLKIHEATGLQIERFQSGPLGGDQQIGALIAANALDLVIFLRDPLTAQPHEPDVSALIRLCDVYSIPLATNMGTAEILVRTLDEGVFEFRDLLRGEEPNV
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: VXIS_BPSFV
Sequence: MQHELQPDSLVDLKFIMADTGFGKTFIYDRIKSGDLPKAKVIHGRARWLYRDHCEFKNKLLSRANG
What is the function of this protein?
Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination at the att site.
What are the official names of this protein?
Probable excisionase hkaC.
What is the protein family that this protein belongs to?
Belongs to the phage alpA excisionase family.
Protein: PANB_ALKEH
Sequence: MYTGDPPQTRRPVTVGRLQRMKADGQKVVALTAYDYTFAVAEDQAGVDVILVGDSLGMVVQGRDTTVPVTVEEMVYHTRCVTAARPSALVMADMPFMSYATLEDGLRNAARLMQEGGAQMIKLEGAGEQAELVARLARAGIPVCAHLGLQPQLVHKLGGYRVQGRESAAADAMLADAQALEAAGADLLLLECVPAELGRRISQGLEIPVIGIGAGPDCDGQILVLQDILGVTPGRIPRFSKNFMNGAGSIQCALQAYVQAVRSGAFPDAAHSFGGQG
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARC_STAAU
Sequence: MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDFSVYKAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRFPNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVRSKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNSDLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKRDAKENLIEVFEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERLSLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSFNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLFIPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKENDDLISVMRFEKDQLITVITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKILQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: G6PI_LACGA
Sequence: MSKVVHFDASKLTPFVHENELKEMQAMVTAADQELREGTGAGSDFRGWIDLPINYDKDEFDRIKKAAKKIQNDSEVLVGIGIGGSYLGAQASIEFLNSSFYGREKEKYPTVVFCGNSLSGSYLYDLLEWLGDKDFSINIISKSGTTTEPSIAFRVLKDKLIKKYGKEEAAKRIYATTDRAKGALKTEADAEGYEEFVVPDDIGGRFSVLSAVGLLPIAVAGGDIDAMMKGAADARAAYTDPDVSKDNPYQYAALRNILYRKGYTTELLENYEPSLRMFGEWWKQLMGESEGKDQKGIYPSSANFTTDLHSLGQYIQEGRRNLMETVIRVESPEHDVTIPDDKENLDQLNFLSGKTMNYVNDRAYEGVVLAHTDGGVPVMTVDIENQSAHTLGYLIYWFELAVGISGYLNGINPFNQPGVESYKRNMFGLLNKPGYEDLHDDLTKRLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_RUTMC
Sequence: MIVIPAIDLKNGQCVRLRQGLMEDTTVFSDSPVEMAEQWVKQGARRVHLVDLNGAFEGRPVNVSSVTEVVSAFPDLPVQIGGGIRNMQIANAYIEAGIDYLIIGTMAVTNPEFVSELCREFPSKVIVGLDANDGLVATQGWTQQTDLNVVNLSKKFEQYGVSSIVYTDIARDGMMQGVNIEATVDLAKQTSIPIIASGGISNMEDIFGLLVEAHHGIMGAIIGRAIYEGTLDFKQAQQFCDAN
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.