PharMolix/UniProtQA huggingface dataset:
Protein: RSMG_PSYA2
Sequence: MSDSTKPSLPSASIGNIHIDPTGFVKLGAQLPTLANILAQAIDELGITLSAQQQRTLLLYLDQLLLWNKAYNLTAITDPVEALIKHVIDCLAIITHLPSGSLLDIGTGAGLPAVIIAICQPERSCTALDSNQKKIRFIKQISSELGLSNMQPIASRIEAHEVSYDVVTSRAFASLIDFVEVAQPRLADNGYLCAMKGKAPSEEERHVLGNDWQFKTIKLNVPRLHDSRHLIELSYKNV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAP1_SOLLC
Sequence: MVGKISSDLPPGFRFHPTDEELIMYYLRYQATSRPCPVSIIPEIDVYKFDPWVLPEKAEFGDNEWYFFTPRDRKYPNGVRPNRAAVSGYWKATGTDKAIYSANKYVGIKKALVFYKGKPPKGVKTDWIMHEYRLSDSKSQTSKQSGSMRLDDWVLCRIYKKKNLGRTIEMMKVEEEELEAQNVSTTNNEIEVVGGPQTMKLPRICSLSHLLELDYFGSIPQLLSDNLLYDDQGYTMNNVNNTSNVDQVSSQQQNTNNITSNNCNIFFNYQQPLFVNPTFQSQ
What is the function of this protein?
Transcription factor that binds DNA motifs 5'-CGT[AG](5N)NACG[ACT][AC][AT][ACG][ACT]-3' and 5'-CACG[ACT][AC][AT][AGT][CT]-3' in target genes promoters.  Promotes leaf senescence and reduces fruit yield and sugar content, probably by establishing abscisic acid (ABA) homeostasis.
What are the official names of this protein?
NAC domain-containing protein 1, SlNAP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: TTCA_DICNV
Sequence: MSVSQNKLCKRLRRLVGKAIDDYQMIADGDRIMVCLSGGKDSYALLDILLALQKSAPIHFEIIAVNLNQKFPNFPERVLPDYLEKLGVKYDIIEHDTYQVVMEKIPAGKTMCSLCSRLRRGILYRYAEEHGITKIALGHHKIDVIETFFLNLFFTGRLKAMPAKLLSDNKKQIVIRPLVYCDEKDIVKYAKLKAFPIIPSNLCGVQKNMQRTIIKEMLLAWEKDYPQRIEHIFAALTKTVPSHLLDTELFNFAEIEQKAIRFCEESD
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_LACP3
Sequence: MASFIDPNQLDLEDQVVSINRVTKVVKGGRRLRFAAIAIVGDKNGHVGFATGKAQEVPEAIRKAVDAAKKSLIEVPIVGTTIPHEVIGHFGAGEVLLKPAEEGSGVAAGGAIRSVMELAGIADITSKSLGRNTPINMIRATMDGLTQLRTREQVAELRGVSASSLED
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: DTDA_THEON
Sequence: MKVIMTTKTDLASMNIMEKLVENFGFKETDRLFDGNPVYSKGDTLILTTNDEMIYYDNLDKAIEHQLGLVPEIIVFASRHSSKQKLPALTTHITGNWGNAMYGGKDESLAIAQPSAMKLALLKMNELNDLNWIICYEATHHGPSELNVPSLFIEIGSSEEEWVNDRAGDILAETITYVLDKYRETKFPVAIGIGGGHYAPKQTKRALETDLAFSHIAPKYVHPLKKELILKAIERTAEKVDAIYVDWKGSKGETRQMAKALAEELGLEFIRD
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: YQGF_MESHJ
Sequence: MGKYNRILALDLGIKTCGFAISDQNWKISYPLEQFNFNRYDFASVISRIAFWMKEYPISILVLGYPLTLAGKISPRTKMVEYFADLVKKNYEIKVVFQDERLTTKQAQTFLLDLGISFKKRQKVIDKLAAQIILERFLNTKKG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADA_ACIB3
Sequence: MATLNPRDVVIVDGVRSAMGKSKNGMFRNVRADSLSAELVRALVARNQFDVNEVEDLIWGCVNQTLEQGMNIGRNIGLLAGLPKTVAGQTVNRLCGSSMQAIHTAAAQIATNQGDIFIIGGVEHMGHVGMMHGIDLNPEASKHYAKASNMMGLTAEMLGRMNGITREEQDAFGVESHRRAWAATQEGRFKNEIIGVEGHDANGFKILCDIDEVIRPDANLEAFKALKPVFDPKGGSVTAATSSALSDGASAMLLMSAERAQALGLKPRAVIRSMAVAGCDAAIMGYGPVPATQKALKRAGLSIADIQTVELNEAFAAQGLSVLKGLGLYDKQDIVNLNGGAIALGHPLGCSGARITTTLLNVMEQQDTQIGLATMCIGLGQGIATVIERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_BACP2
Sequence: MDVVNVMLAGGASRRFGEPKASYMYQGKPLYEHVKKQLLKRQTVIISHPSLLTFFKERGERDVWLDDEQVRGYGPLAGMYTAMQNKEAAWYLVTACDMPFIRRETAEALSSYCSEHVDAIIPLVQGRLQPLFALYHHRCLPAIDACLKENQLAMKDLIQKLKVRIVSEEELNATPNEFRNINKRNDLPENGMI
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2P_LACPA
Sequence: MQRKKKGLSILLAGTVALGALAVLPVGEIQAKAAISQQTKVSSLANTVKAATAKQAATDTTAATTNQAIATQLAAKGIDYNKLNKVQQQDTYVDVIVQMSAAPASENGTLRTDYSSTAEIQQETNKVIAAQASVKAAVEQVTQQTAGESYGYVVNGFSTKVRVVDIPKLKQIAGVKTVTLAKVYYPTDAKANSMANVQAVWSNYKYKGEGTVVSVIDTGIDPTHKDMRLSDDKDVKLTKYDVEKFTDTAKHGRYFTSKVPYGFNYADNNDTITDDTVDEQHGMHVAGIIGANGTGDDPTKSVVGVAPEAQLLAMKVFTNSDTSATTGSATLVSAIEDSAKIGADVLNMSLGSDSGNQTLEDPEIAAVQNANESGTAAVISAGNSGTSGSATQGVNKDYYGLQDNEMVGTPGTSRGATTVASAENTDVISQAVTITDGKDLQLGPETIQLSSNDFTGSFDQKKFYVVKDASGDLSKGAAADYTADAKGKIAIVKRGELNFADKQKYAQAAGAAGLIIVNNDGTATPLTSIRLTTTFPTFGLSSKTGQKLVDWVTAHPDDSLGVKIALTLLPNQKYTEDKMSDFTSYGPVSNLSFKPDITAPGGNIWSTQNNNGYTNMSGTSMASPFIAGSQALLKQALNNKNNPFYADYKQLKGTALTDFLKTVEMNTAQPINDINYNNVIVSPRRQGAGLVDVKAAIDALEKNPSTVVAENGYPAVELKDFTSTDKTFKLTFTNRTTHELTYQMDSNTDTNAVYTSATDPNSGVLYDKKIDGAAIKAGSDITVPAGKTAQIEFTLSLPKSFDQQQFVEGFLNFKGSDGSRLNLPYMGFFGDWNDGKIVDSLNGITYSPAGGNYGTVPLLTNKNTGHQYYGGMVTDADGKQTVDDQAIAFSSDKNALYNDISMQYYLLRNISNVQVDILDGQGNKVTTLSSSTNQTKTYYDAHSQKYIYYNAPAWDGTYYDQRDGNIKTADDGSYTYRISGVPEGGDKRQVFDVPFKLDSKAPTVRHVALSAKTENGKTQYYLTAEAKDDLSGLDATKSVKTAINEVTNLDATFTDAGTTADGYTKIETPLSDEQAQALGNGDNSAELYLTDNASNATNQDASVQKPGSTSFDLIVNGGGIPDKISSTTTGYEANTQGGGTYTFSGTYPAAVDGTYTDAQGKKHDLNTTYDAATNSFTASMAVTNADYAAQVDLYADKAHTQLLKHFDTKVRLTAPTFTDLKFNNGSDQTSEATIKVTGTVSSDTKTVNVGDTVAALDAQHHFSVDVPVNYGDNTIKVTATDEDGNTTTEQKTITSSYDPDVLKNAVTFDQGVKFGANEFNATSAKFYDPKTGIATITGKVKHPTTTLQVDGKQISIKNDLTFSFTLDLGTLGQKPFGVVVGDTTQNKTFQEALTFILDAVAPTLSLDSSTDAPVYTNDPNFQITGTATDNAQYLSLAINGSHVASQYADININSGKPGHMAIDQPVKLLEGKNVLTVAVTDSENNTTTKKITVYYEPKKTLAAPTVTPSTTEPAKTVTLTANAAATGETVQYSADGGKTYQDVPAAGVTVTANGTFKFKSTDLYGNESPAVDYVVTNIKADDPAQLQTAKQALTNLIASAKTLSASGKYDDATTTALAAATQKAQTALDQTDASVDSLTGANRDLQTAINQLAAKLPADKKTSLLNQLQSVKAALGTDLGNQTDPSTGKTFTAALDDLVAQAQAGTQTADQLQASLAKVLDAVLAKLAEGIKAATPAEVGNAKDAATGKTWYADIADTLTSGQASADASDKLAHLQALQSLKTKVAAAVEAAKTAGKGDDTTGTSDKGGGQGTPAPAPGDTGKDKGDEGSQPSSGGNIPTKPATTTSTSTDDTTDRNGQHTSGKGALPKTAETTERPAFGFLGVIVVSLMGVLGLKRKQREE
What is the function of this protein?
Protease which breaks down milk proteins during the growth of the bacteria on milk.
What are the official names of this protein?
PII-type proteinase, Cell wall-associated serine proteinase, LP151, Lactocepin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: TPIS_DEIRA
Sequence: MQTLLALNWKMNKTPTEARSWAEELTTKYAPAEGVDLAVLAPALDLSALAANLPAGIAFGGQDVSAHESGAYTGEISAAMLKDAGASCVVVGHSERREYHDESDAXVAAKARQAQANGLLPIVCVGENLDVRERGEHVPQTLAQLRGSLEGVGADVVVAYEPVWAIGTGKTATADDAEELAAAIRGALREQYGARAEGIRVLYGGSVKPENIAEICGKPNVNGALVGGASLKVPDVLGMLDALR
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_HELAH
Sequence: MVLVKMALGFLILLSPLCAMELDISQTDIIERSLNFLLFVGILWYFLAKKLRSFLHAKSLEISKHLDEIQAQLKASKENKKKLLKELEQAKEKAELIVSDANKEAYTITQKYELQTKIDVENLIKNSKALMDLEVKKIKRELVESVFKDLRESKKVSFSTQDCVNILKQRL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: KTHY_EHRCR
Sequence: MFITFEGIDGSGKTTQSHLLAEYLSEIYGVNNVVLTREPGGTLLNESVRNLLFKAQGLDSLSELLFFIAMRREHFVKIIKPSLMQKKIVICDRFIDSTIAYQGYGQGIDCSLIDQLNDLVIDVYPDITFIIDVDINESLSRSCKNGYEFADMEFYYRVRDGFYDIAKKNPHRCHVITDKSETYDIDDINFVHLEVIKVLQMV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DEX1_CAEEL
Sequence: MLAHTHRINKCLYGQNQMRNRHALLGALPPIFLLLLPLISCMKFDPERIAARLRIDEKWDQLDAFQSIKSRRGRQIQPKEISIQVTAPLFSSRLFDYGTTAGDEELPQALDVGKKLDLVHPISFFGSDYKTIYILSNGAVGFEASSRSYKSGILPSSTRFLAPFWNRNDLRNGGKVYYREVTKGRVLERGQSEIRYQYDKNVKVKSALIITWDKMQPLNTAALPEENTNTFQAAIFITANGTFANFIYSNIGWTQGAEAGFNAGDATNHFKLPTSGTPNIMYLEEYGNTGIPGEWMFELSELRVISCKSGIKGDTCDQECSNGEWGPDCAYCCHCSEGTCHPISGDCQRGCATCWDGVACQTRQEKCATKTQCASNALSFNDYDRCGEPIQRCQCLNGYKGDGYNNCEDVDECKTNSTICHKNAICTNTPGRYFCMCKEGFSGDGQNDCSQSFLFQYDTHHQLPRKKNSKMEWNLKKPLKIFGETTEKLTVTSTGLIAINEVNRDNGRLEDMQLVGIAPFFGPIDLSRNGAVSVEEVDDVEVLRRVTRTIGENYNDPTFVAKSALVVTFSNVTDGRQTKGNTFQALLIDGSNSKNEKMTFVELMYRDLPWASGAEAGILSSDASSSILLPASGTEAISQLSKNSNIKQPGTWLYRIDKAQLMPCAQPIQVPPYCDRLLSTAPRLPSKLLEEKKEGLTLPSPGAFLVDQPSETIVPTLVRGGGTVTRGRNVLTVTTSPIGNQQRQQTTKAVTRPRPNFSSTPHRPIVSLSDEDFELGPDAFEVTFPPFVTVQPELFRPNQRNGVQKSTQRPLPDFSIRTPLKEEATTSVPREKTSSAAPAHSPIEEMSENEESPFEAGSFDGEAVKFNEELEAIDKALQTTKKQRPELSVTPQPEDLSGDARVIETTEEDEEEAEISTETTTEMSSTTTTTKAHTTTTTMMIPTEAPPSIFVFTTTQKPRAQSTTQKRIIVQQPSIVVNSQPPKQRNDNQPTVNVGHAEEQSPRLAILLPVMIILAWLVILVCIGAVVCCKRRNSRESSQLRAMYGAAYGVRPTAYESKRKESTYEDHLERAARLSGQPALSGQQAGKVSLYGSYWNLEPLSNHSPARLSTQERQSPPSFVNNGYTNQTTRYTYAGHY
What is the function of this protein?
Along with dyf-7, enables neurite growth and maintenance by anchoring amphid dendritic tips during neuron cell body migration in embryonic and larval development (PubMed:19344940).  Promotes seam cell remodeling during the dauer phase (PubMed:30409788).  Plays a role in positively regulating locomotion during the dauer phase (PubMed:30409788).
What are the official names of this protein?
Dendrite extension defective protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell projection, dendrite. Secreted. Note=Located at dendritic tips. When transmembrane anchor domain is absent, secreted in vitro.
Protein: BGP11_HUMAN
Sequence: MTAAETGRGKPRLGGGSGLGGSPAAVVWLHVGATGRDAVSPREPVVAAQAAGRPLKLPRRLLRQPTPGLRGAESGPTVDMPVPSSFNDIGQGWRLRHFVSWLWYEREVTLLERWIQDLCTRVVLRIGSAHFYAIVWVNGVDTVEHEGGYLPFEADISSLFQVEPLPSHLCITIAINNTLTPQPCHQGPSVHDRHLQVGTILPPLHAPTFPPHPVVFLPGTGYPKGYFVQNTDFDFFSYAGLLWSLLLYTTPPTYIDDVTVTTGVKRDSGEGFW
What are the official names of this protein?
Putative inactive beta-glucuronidase protein GUSBP11, Beta-glucuronidase pseudogene 11.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: NSP3_ROTHK
Sequence: MLKMESTQQMVSSIINTSFEAAVVAATSTLELMGIQYDYNEVFTRVKSKFDYVMDDSGVKNNLLGKAITIDQALNGKFGSAIRNRNWMIDSKTVAKLDEDVNKLRMTLSSKGIDQKMRVLNACFSVKRIPGKSSSIIKCTRLMKDKLERGEVEVDDSYVDEKMEIDTIDWKSRYDQLEKRFESLKQRVNEKYNAWVQKAKKVNENMYSLQNVISQQQNQIADLQQYCNKLEVDLQGKFSSLVSSVEWYLRSMELPDDVKTDVEQQLNSIDLINPINAIDDIESLIRNLIQDYDRTFLMLKGLLKQCNYEYAYE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: HSLV_LISMF
Sequence: MELHATTIFAVQHDGKAAMAGDGQVTLGESVVMKHTAKKVRRLFHDKVIAGFAGSVADAFTLFEKFEAKLNEYNGNLERASVELAQQWRSDSVLRKLEAMLIVMDKDTLLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKRHNGGQMEAKDIARHALEIASEICVFTNDHITVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_MYCSS
Sequence: MREPLDPLGPALAQASLYLCTDARRERGDLAEFADAALAGGVDLIQLRDKGSAGERRFGPLEAREELAALEILAEAARRHGALLAVNDRADIALAAGADVLHLGQDDLPLPVARRIIGPSPLIGRSTHDSAQVAAAVAEEVDYFCVGPCWPTPTKPGREAPGLGLVREVASRATEKPWFAIGGIDEARLPEVLDAGARRIVVVRAITAADDPKAAARRLKDALVSR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RK22_ADICA
Sequence: MGNVIKSQVGAQALGKNVRVSVTKMQRIIDRIRNCSYEEALVLLEFMPYRACYPVSQLVLSAAANASNNLGLNKSDLFVSKAWVDNSKYLRRFRPRAQGRGYPIKKPTCKVTIQLSSKSIEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PHOSP_MOKV
Sequence: MSKDLVHPSLIRAGIVELEMAEETTDLINRTIESNQAHLQGEPLYVDSLPEDMSRLRIEDKSRRTKTEEEERDEGSSEEDNYLSEGQDPLIPFQNFLDEIGARAVKRLKTGEGFFRVWSALSDDIKGYVSTNIMTSGERDTKSIQIQTEPTASVSSGNESRHDSESMHDPNDKKDHTPDHDVVPDIESSTDKGEIRDIEGEVAHQVAESFSKKYKFPSRSSGIFLWNFEQLKMNLDDIVKAAMNVPGVERIAEKGGKLPLRCILGFVALDSSKRFRLLADNDKVARLIQEDINSYMARLEEAE
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA.  Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus protein P family.
What are the subcellular locations of this protein?
[Phosphoprotein]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Isoform P2]: Host cytoplasm. SUBCELLULAR LOCATION: [Isoform P3]: Host nucleus.
Protein: LIPB_SALTY
Sequence: MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEIGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMR3_YEAST
Sequence: MNFSLSKQSSEKQSSYTDKSRSPNIGMCTVNYKSNLPLQVSAVDQLSTGKGTQFYGHNSYKNERECYNSTKINLPPISSLLPNFENNTPPNVDSRVQFPPQQVYQSMNVVPIVNEIYTPISMNATSDQYPIYYTESQQPIPHSQSPHLTSSAPLMMPVMVPTVYKPLTPYDKEPITIASEPNFTAISMASHPNAALELCHDRPKSVPPGYGVLPTMQEASNGRTKSEPGAVLNGSATFSDWKTDTRISSTKLRKQCPVCGKICSRPSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLRHLKSHERKRNKVLNTT
What is the function of this protein?
Probable transcription factor involved in the regulation of the transcription of genes involved in cell rescue and defense, as well as cell cycle and DNA processing.
What are the official names of this protein?
Zinc finger protein CRM3, Changed mutation rate protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAA_RHOJR
Sequence: MARTSESSPYVEFDRKQWRTLRKSTPLVLTEEELYGLRGLGEQIDLEEVAEVYLPLSRLIHLQVAARQRLFAATATFLGEKHPDQQVPFVIGVAGSVAVGKSTTARVLQALLARWEHHPRVDLVTTDGFLYPTAELNRRGIMHRKGFPESYDRRKLLRFVTEVKSGAEEVAAPVYSHISYDIIPGQYHLIRQPDILIIEGLNVLQTGPRLMVSDLFDFSIYVDARIEDIENWYIQRFLALRKTSFSDPDAHFHHYAGLSDRDATAAAQEIWHNINRPNLVENILPTRPRATLVLRKDANHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNSF_PENEN
Sequence: MGTHDMSPNASHSYIYRVLSDILEFPDNEQRMWWHSVAPMFAEMLRACGYDIHEQYKILGIWKKAVIPFLGCYPTNDGPRWLSILTRYGTPFELSLNCSHRLVRYTFEPINAATGTDKDPFNTQAIWESLSQLRRLNGDVDTELFNHFKANLTVDNAESAHLVESNLAGSKIRTQNKLALDLQNGSFVVKAYFYPTLKSAATGRSITDLMLSSVRQQVQKWSPTLAQPLSVLEEYIEARGPDSTASPRLLSCDLINPERARTKIYLLERQVSIEAMEDLWTLGGRRKSDSALAALDIIREIWSLIQLPPCLASYPSGYLPLGTVPDEQLPLMVNYTLRPDDPMPEPQVYFTTFGQNDLHVTNALTAFFERQGWTELAESYKENLRAYYPHADQETANYIHAYVSFSYRKGVSYMSVYLQTLETGDWPITYSPKRQYLCNEHPIHLKELAKACA
What is the function of this protein?
Tryptophan dimethylallyltransferase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals (PubMed:25571861).  Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptophan (PubMed:25571861).  The L-tryptophan decarboxylase cnsB converts L-tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L-tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the aurantioclavine synthase cnsA, probably aided by the catalase cnsD (PubMed:25571861).  The cytochrome P450 monooxygenase cnsC catalyzes the heterodimeric coupling between the two different indole moieties, tryptamine and aurantioclavine, to construct vicinal quaternary stereocenters and yield the heptacyclic communesin scaffold (PubMed:26963294).  The O-methyltransferase cnsE then methylates the communesin scaffold to produce communesin K, the simplest characterized communesin that contains the heptacyclic core (PubMed:25571861).  The dioxygenase cnsJ converts communesin K into communesin I (PubMed:25571861).  Acylation to introduce the hexadienyl group at position N16 of communesin I by the acyltransferase cnsK leads to the production of communesin B.  The hexadienyl group is produced by the highly reducing polyketide synthase cnsI, before being hydrolytically removed from cnsI by the serine hydrolase cnsH, converted into hexadienyl-CoA by the CoA ligase cnsG, and then transferred to communesin I by cnsK (PubMed:25571861).  Surprisingly, cnsK may also be a promiscuous acyltransferase that can tolerate a range of acyl groups, including acetyl-, propionyl-, and butyryl-CoA, which lead to communesins A, G and H respectively (PubMed:25571861).  The roles of the alpha-ketoglutarate-dependent dioxygenases cnsM and cnsP have still to be determined (PubMed:25571861).
What are the official names of this protein?
Tryptophan dimethylallyltransferase cnsF, 4-dimethylallyltryptophan synthase, DMATS, All-trans-hexaprenyl-diphosphate synthase, Communesin biosynthesis cluster protein F, L-tryptophan dimethylallyl transferase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: HIPK4_RAT
Sequence: MATIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRSRIIKNELKLLRCVRGLDPDEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLRALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAARKAHHFFKRNPHPDATNPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGGAVNRLSFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHEATRYYQLSLRGCRLSLQVDGKPPPPVIANAEDGPPYYRLAEEEETAGLGGVTGSGSFFREDKAPGMQRAIDQLDDLSLQEARRGLWSDTRADMVSDMLAPLKVATTSHRVPDSGPEPILAFYGSRLTGRHKARKAPAGSKSDSNFSNLIRLSQASPEDAGSCRGSGWEEGEGHTTSTEPSAIPQREGDGPSIKDRPMDAERSGPELFDPSGCPGEWLNEPEWTLEGIRGSRAQGLPARHPHPHGPPRTTSFLQHVGGHH
What is the function of this protein?
Protein kinase that phosphorylates TP53, and thus induces TP53 repression of BIRC5 promoter (By similarity).  May act as a corepressor of transcription factors (Potential).
What are the official names of this protein?
Homeodomain-interacting protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.