PharMolix/UniProtQA huggingface dataset:
Protein: HXA5A_DANRE
Sequence: MSSYFVNSFCGRYPNGVDYPLHNYGDHNSSGQCRDSTGMHSGRYACGYNGMDLSTGHSSPGHFLSSGERTQSYKDSPTATPVRYNQPVTASSAEPSSDHLPCSSLANSPVSEQSHRALKISLSSTAGSASKSFGTVLSREGVSKVSSSMEEEKPPGSGQTASQNVSEAPQIYPWMRKLHISHDNLAGPEGKRPRTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDNKLKSMNMAAAGSGYRP
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A5a.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1963_CALS4
Sequence: MKGRMKLRLVLDTHTHTIASGHAFSTIIENAREAFRKGLQLICITDHGPEMPGGPHIYYFGNLKVIPEKIEGVEILKGVEANIMDEEGRIDLPERILKKLDIVIASLHDECFEPSEDVERNTKALINAIKNPYVDIIGHPGNPIYPIDIERVLEAAKEYGKFIEINNSSFVTSRRGSEKICPIIAGKAKEMGVRVAVGSDAHICFDVGRFDEAIRLLEDINMPEELVLNTSVDKVKQYLQEKRKRIGGGQNSWN
What are the official names of this protein?
Probable phosphatase TTE1963.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: SWA2_ARATH
Sequence: MSKIKPLSKSSQDLSLLTSDIASFASSIGLASALPSSGFNDTDFRKPAKSKTQKRKKPKKDQQHKDEDEEGEPKSNIGNEKGKDFGARKQNKDAPVKQTLQPKPKPGFLSIDDESTGYKKKRFDEFKSLPKLPLVKASLLSSEWYNDAAEFEEKVFGGRKVAVANKEDFKGVVEKKRELGERLMWQYAEDFATSKGKGGDMKMVISAQKSGTVADKITAFEIMVGENPIANMRSLDALLGMVTSKVGKRFAFKGLKALSEILIRLLPDRKLKSLLQRPLNIIPENKDGYSLLLFWYWEDCLKQRYERFVTALDESSKDMLPELKDKALKTIYFMLTSKSEQERKLLVSLVNKLGDPQNKSASNADYHLTNLLADHPNMKAVVIDEVDSFLFRPHLGLRAKYHAVNFLSQIRLSHKGEDPKVAKRLIDVYFALFKVLTTEANRKQGADDKGAADKKKSNPKDTKQEVSTDSPIELDSRILSALLTGVNRAFPYVSTDEADDIIESQTPVLFKLVHSANFNVGVQSLMLLDKISSKNKIVSDRFYRALYSKLLLPSAMNSSKAEMFIGLLLRAMKNDINIKRVAAFSKRVLQVALQQPPQYACGCLFLLSEVLKSRPPLWKMVVQRESVEEEEDIEHFEDVIEGDDVDPNKKAENDENVVEVDHDGVEKSSRDGDSSSDDEEALAIRLSDEEDDNASDDSEELIRNETPQLEEVMEVSNDMEKRSQPPMRPSSLPGGYDPRHREPSYCNADRASWWELGVLSKHAHPSVATMAGTLLSGTNIVYNGNPLNDLSLTAFLDKFMEKKPKQNTWHGGSQIEPSKKLDMSNRVIGAEILSLAEGDVAPEDLVFHKFYVNKMTSTKQSKKKKKKKLPEEEAAEELYDVNDGDGGENYDSDVEFEAGDESDNEEIENMLDDVDDNAVEEEGGEYDYDDLDGVAGEDDEELVADVSDAEMDTDMDMDLIDDEDDNNVDDDGTGDGGDDDSDGDDGRSKKKKKEKRKRKSPFASLEEYKHLIDQDEKEDSKTKRKATSEPTKKKKKKKSKASE
What is the function of this protein?
Together with NOC2, probably involved in pre-ribosome export from the nucleus to the cytoplasm (PubMed:19734265).  Required for coordinated cell cycle progression during female gametophyte and pollen development (PubMed:19734265, PubMed:15634699).
What are the official names of this protein?
Protein SLOW WALKER 2, Protein EMBRYO SAC DEVELOPMENT ARREST 25.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: FPG_SALSV
Sequence: MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRLSDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILSEALPAEKHDHVDLVMSNGKILRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSTEECDLLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: METK_ALKEH
Sequence: MSEYLFTSESVSEGHPDKMADQISDAVLDAILAEDPRGRIACETMIKTGIIILGGEVTTSANIDYEAVARETVKRIGYKHHEMGFDGETCGVINILGKQSVDIAQGVDRDHPEEQGAGDQGLMFGYASNETDVLMPAPITYAHRLVQRQAEVRCNGQLPWLRPDAKSQVTLRYVDGRPVAVDTVVLSTQHAPDLTQAQVHEAVIEEIIKPVLPEQWITGETRYLVNPTGRFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSAAYACRYVAKNIVAAGLAERCEIQVSYAIGVAEPTSISVETFGTGRVDSEKLTRIVREHFDLRPYGILKMLDLIRPIYTATAAYGHFGREDEGFPWERIDRAEEIRDAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_SALTY
Sequence: MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPKQMLAELRSFVSAMKAASRA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: STS1_STEHR
Sequence: MAVATSVATPVPTPAYSAGRAPAKEKKIYLPDTLAEWPWPRAINPHYAEAKEESQAWAASFNAFSPKAQHAFNRCDFNLLASLAYPLATKHGCRSGCDLMNLFFVIDEYSDIAPVEEVRQQKDIVMDALRNPHKPRPEGEWVGGEVARQFWALTITNASAQSQKHFIETFDEYLDSVVQQAEDRSESRIRDIQSYIDVRRNTIGAKPSFALLELDMDLPDEVLAHPTIQSLSLATIDMLCLGNDIVSYNLEQARGDASHNIITIVMNELNLDVNGAMRWVGDFHKQLEKQFFEAFNNLPKWGNAELDAQIAVYCDGLGNWVRANDQWSFESERYFGARGLEIMETKTLAMMPIQRTEALGPQLVDDSIL
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to delta(6)-protoilludene (PubMed:24166732, PubMed:26239156).  In presence of Ca(2+), a significant switch from 1,11 to a dual 1,11/1,10 cyclization occurs, producing beta-elemene as the major product, with lower levels of delta(6)-protoilludene and (E)-beta-caryophyllene, and traces of beta-selinene and alpha-selinene (PubMed:26239156).
What are the official names of this protein?
Delta(6)-protoilludene synthase STEHIDRAFT_73029, Terpene cyclase STEHIDRAFT_73029.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: HISZ_ACIAC
Sequence: MSAWVLPDHIADVLPSEARHIEELRRGLIDTARGYGYELVMPPMLEHLESLLSGTGEALDLQTFKLVDQLSGRSIGLRADMTQQVARIDAHLLNRSGVTRLCYCGPVLHTRPDRPRATREPLQFGAEIYGHSGMEADLESVLLALDCLHLAGVEGVSVDLSDARVVRTLLEPIAADSATVRRIYAALAAKDASELSQASAGLPSGTRRALSAVLELYGDASVLDEARTALSDVAGVEEVLANLKSIAAHLEGRTVSFDLADLRGYSYYSGARFTIYARNATDAVVRGGRYDEVGAAFGRTRPAAGFSLDIKQLVGIVPPRTLKAAIRAPWAATPDAHRFIAQLRSAGETVVCVLPGHESQVQEFQCDRELVLEQGQWMVRPLPY
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOB1_YEAST
Sequence: MSLEGNTLGKGAKSFPLYIAVNQYSKRMEDELNMKPGDKIKVITDDGEYNDGWYYGRNLRTKEEGLYPAVFTKRIAIEKPENLHKSPTQESGNSGVKYGNLNDSASNIGKVSSHQQENRYTSLKSTMSDIDKALEELRSGSVEQEVSKSPTRVPEVSTPQLQDEQTLIQEKTRNEENTTHDSLFSSTADLNLSSESLKNISKSNISTKSLEPSSESVRQLDLKMAKSWSPEEVTDYFSLVGFDQSTCNKFKEHQVSGKILLELELEHLKELEINSFGIRFQIFKEIRNIKSAIDSSSNKLDADYSTFAFENQAAQLMPAATVNRDEIQQQISSKCNKLSSESSDRKSSSVTTELQRPSSVVVNPNFKLHDPAEQILDMTEVPNLFADKDIFESPGRAPKPPSYPSPVQPPQSPSFNNRYTNNNARFPPQTTYPPKNKNPTVYSNGLIPNSSTSSDNSTGKFKFPAMNGHDSNSRKTTLTSATIPSINTVNTDESLPAISNISSNATSHHPNRNSVVYNNHKRTESGSSFVDLFNRISMLSPVKSSFDEEETKQPSKASRAVFDSARRKSSYGHSRDASLSEMKKHRRNSSILSFFSSKSQSNPTSPTKQTFTIDPAKMTSHSRSQSNSYSHARSQSYSHSRKHSLVTSPLKTSLSPINSKSNIALAHSETPTSSNNKEAVSQPSEGKHKHKHKHKSKHKHKNSSSKDGSSEEKSKKKLFSSTKESFVGSKEFKRSPSELTQKSTKSILPRSNAKKQQTSAFTEGIRSITAKESMQTADCSGWMSKKGTGAMGTWKQRFFTLHGTRLSYFTNTNDEKERGLIDITAHRVLPASDDDRLISLYAASLGKGKYCFKLVPPQPGSKKGLTFTEPRVHYFAVENKSEMKAWLSAIIKATIDIDTSVPVISSYATPTIPLSKAQTLLEEARLQTQLRDAEEEEGRDQFGWDDTQNKRNSNYPIEQDQFETSDYLESSAFEYPGGRL
What is the function of this protein?
Binds to the BEM1 protein.
What are the official names of this protein?
Protein BOB1, BEM1-binding protein, Growth inhibitory protein 7.
Protein: G6PI_MYCGE
Sequence: MSDKLLTIDLSHVYGFDKEIIFKKYQKKVDQIHQDFLAHKLADGHMTGWYDQPDQNHQFLLKTINQIDKKFKSLKVTDIVYVGIGGSFTGIKTVLDFLKPKQRTGLKIHFVPDLSAFQAASVIKEIKNKSWALITTSKSGRTLEPALNFRIFRNLLNKRYGNKHYQRVVVITDEKKGLLTKMASNHGYQKLVIDSNIGGRFSTLSPAGLLLAKLFGHDPKAILKGTLQAKKDLQTTSLENNSAYLYAVVRHWLYTTKKFKIEVCIAYHSLYEYLLLQHRQLFGESEGKNDKSLFPTFSIFTVDLHSMGQLYQEGEKVFFETVIDVKNPLVNINLPPSDFDNDDELDFLLDKSLNEISDVAIDSVIKAHYQANVSIIKLTLKEQSAFMFGYFYFWLSVATVMSGSLLGHNVFNQPGVEVYKKLMFEKLRSGH
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_SALDC
Sequence: MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIYECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEIADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYTGYSFAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVCDMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNAQIQARQLYHDREEVTVHVRRLWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_TERTT
Sequence: MLVWLANFLESYVSGFGVFQYLTLRAILGVLTALGLSMVLGPWVIRKLNELQIGQAIRDDGPQSHLSKSGTPTMGGTLILFSIVTATLLWADLSNRYVLAVLFVTITFGLIGWVDDYRKVVEKNSKGLPAKWKYFWQSACGFIVAIALFVTAQTPAETTLYIPFFKNVAWQMGVLYVFVTYLMIVGFSNAVNLTDGLDGLAIMPTVMVGSALGVIAYLVGNANFSEYLHIAFVPGSGELVVYCAALAGAGLGFLWFNTYPAQVFMGDVGALALGAALGVIAVIVRHEIVFFIMSGIFVMETVSVILQVGSYKLTGRRIFRMAPLHHHFELKGWPEPRVIVRFWIITVILVLFGLATLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCNS1_SAIBB
Sequence: MLMLLVRGTRYENHRSKVTLPTPLGGRSNETTLCESPGPDTGIRWRRSDEALRVNVGGVRRLLSARALARFPGTRLGRLQAAASEEQARRLCDDYDAAAREFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRVTRPRAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSAEGVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGAALGDQGGTGGKEFGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEEHVGFDTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRNSNHQEFEDLLSSVDGVSEASLETSRETSQEGRSADLETQAPSEPPHAQMY
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.
What are the official names of this protein?
Potassium voltage-gated channel subfamily S member 1, Delayed-rectifier K(+) channel alpha subunit 1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2.
Protein: CARL2_MOUSE
Sequence: MAQTPDDISCELRGEITRFLWPKEAELLLKTWLPQEGAEQSHILALLRWRAYLLHTCLPLRVDCTFSYLEVQAMALQETPPRVTFELESLPELVLEFPCVAALEQLAQHVAAAIKKVFPRSTLGKLFRKPTPSSLLARLERSHPLESTIPSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQGCRHFCLGDFSHFGSRDLALSVAALSYNLWFRRLSCEDMKLSLEVSEQILHMTSQSSYLEELVLEACGLRGDFVRRLAQALAGHFNSGLRELSLSGNLLDDRGMRALGRALATNATFDSTLTHLDLSGNPGALGPSQDSGGLYTFLSRPNVLAYLNLAGTDATLGTLFTALAGGCCSSLTHLEASRNIFSRMKSQAAPAALQRFLGGTRMLRHLGLAGCKLPPEALRALLEGLALNTQIHDLHLDLSACELRSVGAQVIQDLVCDAGALSSLDLSDNGFGSDMVTLVLAIGRSRSLKHVALGRNFNVRCKETLDDVLHRIAQLMQDDDCPLQSLSVAESRLKQGASILIRALGTNPKLTALDISGNAIGDAGAKMLAKALRVNTRLRSVIWDRNNTSALGLLDVAQALEQNHSLKSMPLPLNDVTQAHRSRPELTTRAVHQIQACLWRNNQVDSTSDLKPCLQPLGLISDHSEQEVNELCQSVQEHMELLGCGAGPQGEVAVHQAEDAIQNANFSLSILPILYEAGRSPSHHWQLQQKLESLLGQVGEICRQDIQDFTQTTLDTTRSLCPQMLQTPGWRKQLEGVLVGSGGLPELLPEHLLQDAFSRLRDMRLSITGTLAESIVAQALAGLHAARDRLVERLTQQAPVTMAPAVPPLGGNELSPLETGGLEELFFPTEKEEEREKVLLRKRNGTPSWQLRGKMQSRRLGRLHAVAEKHWAAGPRDTPASAVYQRVDVCVGWVPPALLQEGNGLTARVDEGVEEFFSKRLIQQDHFWAPEEDPATEGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPGAAARARKSTLGDLLRPPARPGRGEEPGGAEGGTSSPDPARRNRPRYTRESKAYSMILLPAEEEAAVGTRPDKRRPLERGDTELAPSFEQRVQVMLQRIGVSRASGGAESKRKQSKDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGPGGQGPESATWKTLGQQLNAELRGRGWGQQDGPGPPSPCPSPSPRRTSPAPDILSLPEDPCLGPRNEERPLRLQRSPVLKRRPKLEAPPSPSLGSGLGSKPLPPYPTEPSSPERSPPSPATDQRGGGPNP
What is the function of this protein?
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments.  Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization.  Plays a role in cell protrusion formations; involved in cell polarity, lamellipodial assembly, membrane ruffling and macropinosome formations.  Involved as well in cell migration and invadopodia formation during wound healing (By similarity).  Required for CD28-mediated stimulation of NF-kappa-B signaling, involved in naive T cells activation, maturation into T memory cells, and differentiation into T helper cells (PubMed:27647348).  Required for CD28-mediated differentiation of T regulatory cells (By similarity).
What are the official names of this protein?
Capping protein, Arp2/3 and myosin-I linker protein 2, Capping protein regulator and myosin 1 linker 2, F-actin-uncapping protein RLTPR, Leucine-rich repeat-containing protein 16C, RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein.
What is the protein family that this protein belongs to?
Belongs to the CARMIL family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, ruffle. Note=Colocalizes to dynamic vimentin filaments both in the central cytoplasm and at leading edges of migrating cells. Colocalizes with F-actin, Arp2/3 complex and cortactin to leading edge lamellipodia, ruffles and macropinosomes of migrating cells.
Protein: PLS2_PITNO
Sequence: FLSLIPSLVSGAVSLVKK
What is the function of this protein?
Antimicrobial peptide with low activity against Leishmania species (L. amazonensis and L. infantum) (PubMed:23774944).  Shows low cytotoxicity against mammalian cells in models of peritoneal macrophages (PubMed:23774944).
What are the official names of this protein?
Phylloseptin-N2, PLS-N2, Phylloseptin-H8b, PLS-H8b.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBR_COCNU
Sequence: MSQASVDMEDVKPSISLPSDDGGAMEARLTDVCKSKLALDESTMRQAMILFRESKHILLANMSAIGSGSPEEIERFWSAFVLYCVTRLSKGRTKQEKEENGITLCRILRVLKMNVVDFFKEIPQFCLKAGYILTGLYGSDWEKRLELKELQANIVHLSLLSRYYKRAYQELFLPNDASSGRHSVAPNSVGYVSDYHHFGWLLFLALRIHAFSRFKDLVTCTNGLVSILAILILHIPARFRNFHIQDSLLFAKRTAKGVDLVASLCDKYHTSEDELRRVMEKANNLIVDILKKKPCAASECKRENLAYINTDGLIYFEDLLEENSLQSSILILEDNYDDAINSKGELDERMFVNDEDSLLGSGSLSGGSIKMKRKYDAMASPAKSITSPLSPPLSPASPVNGNPVIKMVPITPVSTAMTTAKWLRNIISPLPSRPSTELLCFFSSCDRDITTDVTRRASIILGAIFPTTSFGDCCISGNLQSVNQMDSIWAEQRKVEAMKLYYRVLETMCRAESHILNGNNLTSLLSNDRFHRCMLACSAELVLATHKTVTMMFPAVLEKTGITAFDLSKVIESFVRHEETLPRELKRHLNSLEERLLESMAWERGSSMYNSLIVARPTLAAEINRLGLLAEPMPSLDAIAVHNNISTGGLPPLPFQKHEHSSDQNGGAVSPKRACSEYRSVLVERNSFTSPVKELTLTLNLKSKLPPLQSAFASPTRPNPAGGGETCAETGINIFFNKIVKLAAIRIRSLCERLQLPQQILEWVYCLIQQILSQRTALFFNRHIDQIILCSFYGVAKISQMALTFKEIIYNYRKQPQCKPQVFRSVFVHWPSTSHNGKTGQEHVDIITFYNEVFIPSVKPLLVELGPAGVAQKSKSSPEDSNNADSQIPGSPRLSPFPNLPDMSPKKVSAAHNVYVSPLRSSKMDALLSPSSKSYYACVGESTHAYQSPSKDLTAINNRLNSGRKVSGRLNFDVVSDSVVAGSLGAQNGSSAPAPACSILELPVKREQPDS
What is the function of this protein?
Regulator of biological processes that recruits a histone deacetylase to control gene transcription.  May play a role in the entry into mitosis, negatively regulating the cell proliferation.  Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).
What are the official names of this protein?
Retinoblastoma-related protein.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FMT_PSEF5
Sequence: MTEPLRIVFAGTPEFAAEHLKALLDSPYQIVAVYTQPDRPAGRGQKLMPSPVKQLALENDIPVLQPPTLRNAEAQAELAALKPDLMVVVAYGLILPQAVLDIPRLGCINSHASLLPRWRGAAPIQRAVQAGDAQSGVTVMRMEAGLDTGPMLLKVSTPISAEDTGGSLHDRLAEMGPPAVLQAIEGLAAGTLEGEVQDDSLATYAHKLNKDEARIDWSRPAVELERLVRAFNPWPICHSSLNGEALKVLAATLAEGKGAPGEILGASKDGLIVACGEQALCLTRLQLPGGKALNFSDLFNSRREKFAIGTVLGQTADAQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RK14_CHLRE
Sequence: MIKPLSYLNVADNSGARELMCIRALGGSYRESANIGDVIIAVVKDALPNMPVKRSDIVRAVIVRTRKGIRRENGMAIRFDDNAAVIINKEGNPRGTRVFGPIARELRDKNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS16_UREU1
Sequence: MKILVKIRLTRVGTHKKPFFRIVVMDAKAKANGAYIENLGHYDPVLGKVVLKKEAILAQLQNGAQPSETVKNILSQEGIWKEFIALKDANKKRKAALAKAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SYDND_BURTA
Sequence: MSMRTEYCGLVTEHLLGQTVSLCGWVQRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFATAEGVRNEFCVQVKGLVRNRPEGTVNAGLKSGKIEVLCHELTVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFIDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETSFLGEQEIRDLFEDMIRHIFKTTIDVELDAKFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDGRVAALRVPKGAELTRGDIDGYTEFVRIYGAKGLAWIKVNERAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIVFFAADRAKVVNDSLGALRLKIGHSEFGKANGLVESGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLAKAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDVIAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_ACTSZ
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRTVDKSWVERVAEVIDIPFCVAGGIKTIADAEQIFAFGADKISINSPALADPNLITALADRFGVQAIVVGIDSWFEKETGKYWVNQYTGDESRTRQTNWQLLDWVKEVQQRGAGEIVLNMMNQDGVRNGYDLVQLKKVREVCKVPLIASGGAGETVHFRDAFVEANVDGALAASVFHKQIINIGELKAYLTKEGVEIRR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_CENSY
Sequence: MKATKMRNRQIYQASTRTRSMQVGSPLSKELRAKYGKRSVRVVEGDTVSVVRGEYKDIDGKVSHVDTESGSVAIEGIKKEKGKGDKFDVLIRASKVVVTGLNASDSWRMKKLGGTAEPAAKADSEDAASVGKAEPEDSGIDDATEPEQAGAAGAESHDAEAPREESK
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ANGL7_BOVIN
Sequence: MLKKTLSAVAWLCIFLVAFVSHPVWPQKPPKRKTPAELTAATCCEEAKALQAQIANLSSLLSDLGKKQERDWVSVVMQVMELESSAKSMETRLTEAESKYSEMNNQIGIMQLQAAQTVTQTSADAIYDCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYRDWKQYKQGFGSIRGDFWLGNDHIHRLSRRPTRLRVEMQDWEGNMRYAEYSHFVLGNELNSYRLFLGNYSGDVGNDALIYHNNTAFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHNKHLDGITWYGWHGSSYSLKRVEMKIRPEDFQP
What is the function of this protein?
Has a role in the formation and organization of the extracellular matrix.  In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure.  Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency.
What are the official names of this protein?
Angiopoietin-related protein 7, Angiopoietin-like protein 7.
What are the subcellular locations of this protein?
Secreted.
Protein: AIM36_LODEL
Sequence: MFRFQRIGQQLVRRETFLHSPRAKLVQPYLFNSQRQYVIVHKDLQKAKKEPRIRYILYMIALSWAAIFFVSSKVDKKKPMQSMTEREFQEYEKQTGIKRRHKLIHSDQNSKYKFYVIPYIYNNEQIEKIEQSLAKSDPNRKNVVIDPAKLVLEEKEDEGAKYSALLNDLDAMKKPYPPGLITAIIKQHINLLINTREGTFDTNYIIKNYPQTTGEAIKFENDIGDISKCLIMHYDMLNELPQQLPEEKVRNIRNVEGYFDSVNKAQTMVSKFDIMDEKFEEIILEDL
What are the official names of this protein?
Altered inheritance of mitochondria protein 36, mitochondrial, Found in mitochondria protein 39.
What is the protein family that this protein belongs to?
Belongs to the AIM36 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.