PharMolix/UniProtQA huggingface dataset:
Protein: PCRB_STAA2
Sequence: MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRIRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: DEF_BACFN
Sequence: MILPIYVYGQPVLRQVAEDITVDYPNLKELIENMFETMDHADGVGLAAPQIGLPIRVVVINLDVLSEDYPEYKDFRKAYINAHIDVVEGEEVSMEEGCLSLPGIHESVKRGSKIHVRYMDENFVEHNEVVEGFLARVMQHEFDHLDGKMFIDHISPLRKQMIKGKLNTMLKGKARSSYKMKQVK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ECHP_PONAB
Sequence: MAEYTRLHNALALIRLRNPPVNAISTALLRDIKEGLQKAVIDHTIKAIVICGAEGKFSAGADIHGFSAPRTFGFTLGHVVDEIQRNEKPVVAAIQGMAFGGGLELALGCHYRIAHSEAQVGLPEVTLGLLPGARGTQLLPRLIGVPAALDLITSGRHILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDTIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGVKKEEELFLYLFQSGQARALQYAFLAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSMKELGGVDLVIEAVFEEMSLKKQVFAELSAICKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLPPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKADPWLSKFLSQYRETHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPDIPQLEPSDYLKKLASQGNPPQKEWQSLAGSPSSKL
What is the function of this protein?
Peroxisomal trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities.  Catalyzes two of the four reactions of the long chain fatty acids peroxisomal beta-oxidation pathway (By similarity).  Can also use branched-chain fatty acids such as 2-methyl-2E-butenoyl-CoA as a substrate, which is hydrated into (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA (By similarity).  Optimal isomerase for 2,5 double bonds into 3,5 form isomerization in a range of enoyl-CoA species.  Also able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (By similarity).  Regulates the amount of medium-chain dicarboxylic fatty acids which are essential regulators of all fatty acid oxidation pathways (By similarity).  Also involved in the degradation of long-chain dicarboxylic acids through peroxisomal beta-oxidation (By similarity).
What are the official names of this protein?
Peroxisomal bifunctional enzyme, PBE, PBFE, Multifunctional enzyme 1, MFE1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MODC_AROAE
Sequence: MSGAVPFGAGAVRTGAITGDEAIRARFGLGWPGFRLDVDLALPGRGVIALFGHSGSGKTTLLRCLAGLERAADGYLAVRGELWQDEAQRLFVPTHRRPLGYVFQEASLFAHLTVRRNLEFGLKRVPAASRRIPLDQAIALLGIEPLLDRMSGRLSGGERQRVAIARALATSPRLLLMDEPLAALDVKRKQEILPYLERLHAELDIPVVYVSHAPEEVARLADHVVLLADGRALAAGPIGEVMARLDLPFAHDEDAFVVIDARVAAHDEAYALTRLEFAGLPLWITGLDMPLASRVRARVLARDVSLALTERHDSSILNVLPARVVSLDEADPGRTLVRLDVAGTALLARITRRSAAQLGIVPGRDVYAQVKGVALLR
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SBT46_ARATH
Sequence: MATAVSYCLLSCIFALLVVSFASAGKDDQDKQVYIVYMGALPSRVDYMPMSHHTSILQDVTGESSIQDRLVRNYKRSFNGFAARLTESEREILASMDEVVSVFPSKNLNLQTTTSWNFMGLKEGKRTKRNPLIESDTIIGVIDSGIYPESDSFSGKGFGPPPKKWKGVCKGGTNFTCNNKLIGARYYTPKLEGFPESARDNTGHGSHTASIAAGNAVKHVSFYGLGNGTVRGGVPAARIAVYKVCDPGVIRCTSDGILAAFDDAIADKVDIITVSLGADAVGTFEEDTLAIGAFHAMAKGILTVNGAGNNGPERRTIVSMAPWLFTVAASNMNRAFITKVVLGNGKTIVGRSVNSFDLNGKKYPLVYGKSASSRCDASSAGFCSPGCLDSKRVKGKIVLCDTQRNPGEAQAMGAVASIVRNPYEDAASVFSFPVSVLSEDDYNIVLSYVNSTKNPKAAVLKSETIFNQKAPVVASYSSRGPNPLIHDILKPDITAPGSEILAAYSPYVPPSESDTRHVKYTVISGTSMSCPHVAGVAAYIKTFHPLWSPSMIQSAIMTTAWPMNASTSPSNELAEFAYGAGHVDPIAAIHPGLVYEANKSDHITFLCGFNYTGKKLRLISGDSSSCTKEQTKSLTRNLNYPSMSAQVSGTKPFKVTFRRTVTNVGRPNATYKAKVVGSKLKVKVVPAVLSLKSLYEKKSFTVTVSGAGPKAENLVSAQLIWSDGVHFVRSPIVVYA
What are the official names of this protein?
Subtilisin-like protease SBT4.6, Subtilase subfamily 4 member 6, AtSBT4.6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y999_STAA1
Sequence: MRLYINEIKIKDDILYCYTEDSIKGLSEVGQMLVDSDNYAFAYTLDDGKAYAYLIFVQETWTMLHENTTKKIIINDELELTEFHQELTYILDNIKGNNNYGKEFVATVEETFDIE
What are the official names of this protein?
UPF0738 protein SAHV_0999.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: GSTU6_ORYSJ
Sequence: MAGSGELKLLGVWSSPYAIRVRVVLNLKSLPYEYVEENLGDKSDLLLASNPVHKSVPVLLHAGRPVNESQVIVQYIDEVWPGGAGGRPSVMPSDPYERAVARFWAAYVDDKVRPAWLAILFGSKTEEERAAAVAQAVAALETLEGAFGECSKGKPFFGGDGVGFVDVVLGGYLGWFTAIDKLIGRRLIDPARTPALAAWEERFRATDAAKGVVPDDADKLLEFRQTLLRWSASKAK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Probable glutathione S-transferase GSTU6, 28 kDa cold-induced protein.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
Protein: COXX_SYNP6
Sequence: MTLSSDSRLRFPLEEVGAQLLAYWQLTKPRIILLLLITTAAGMGLAAQGPLDPRLAIATLIGGGLAAAAANTLNCLYDRDIDAIMERTRWRPLPSGRIQPFEAWAFALSLAALSFILLDWQANQLAAGLALAGIVFYVVIYTHGLKRHSSQNIVIGGAAGAIPPLVGWAAVTGELAWPAWILFAIVCLWTPPHFWALALMIRDDYAAVKVPMLPVVVGNAATAQQILAYAGLLLPTTLALAWPLGAAGPFYSATALLLGLELLRRSRQLCQAPDSRPLARSLFKFSIFYLMLLCGAIAMDCLPGAPSLSQAIAAWPGF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOK1_STRGG
Sequence: MNPVNYLYLAALLFAIGASGVLVRRNAIVVFMCVELMLNACNLALVTFSRMHGNLDGQIVAFFTMVVAAAEVVVGLAIIVSLFRSRHSASVDDASLMKL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 1, NADH dehydrogenase I subunit K 1, NDH-1 subunit K 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1338_LEPBA
Sequence: MAQDPSFDIVSKLERPELQNAVSQAMTEIQTRFDFKGSNSEIKITDDQLVLTSENEIKLKQVIDVLTTKMAKRGIGLKAFDFDSKVESATGQTVRMKVKIQNGLDKEQTKQITTLIKDQKLKVQATIQGDSVRVVGKKKDDLQEVMAAIRNANFNFDANFTNFKG
What are the official names of this protein?
UPF0234 protein LBF_1338.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: NUSB_BACAN
Sequence: MKRRTARERAMQALYQMDITGELEPKVAVENTLDEGEETNEFLESLVVGFVENKEVIDEAIRQNLKKWKLERISIVDRSILRVAVYEMKYMEEIPHNVTINEAIEIAKTFGDEESRRFINGVLSNIKDTL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CASP1_HUMAN
Sequence: MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
What is the function of this protein?
Apoptosis inactive.
What are the official names of this protein?
Caspase-1, CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: FABH_BRADU
Sequence: MTKIRSVVLGCGSYLPEQVVTNAQLAARIDTSDEWIVQRTGIRERHIAAEGEFTSHLAIKAAQAALTDAGVDAQSIDLIVLATSTPDNTFPATAVAVQHGLGINHGAAFDLQAVCSGFVFALATADNFLRTGAFKRALVIGAETFSRILDWNDRGTCVLFGDGAGAVVLEAQEQPGSAATDRGVVTTHLRSDGRHKAKLFVDGGPSSTQTVGHLRMEGREVFKHAVGMITDVIVDAFEATGLNADSIDWFVPHQANKRIIDASAHKLHIAPEKVVLTVDRHGNTSAASIPLALAVARKDGRIKRGDLILLEAMGGGFTWGSALVRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_MARMS
Sequence: MKDLLPDLCDLYPEKLQIAEPIFTSYGKRSHFYGEVVTVSCFEDNSRVRELVAENGKGKVMVIDGGGSKRRALLGDMLAEKAVDNGWEGFVINGAIRDIAAQSQLNIGIHALCAHPMPTEKRGLGDLGKTLRFAGMTIAQGDYIYCDLNGIVVSKQPLALP
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: FN3K_MOUSE
Sequence: MEQLLRAQLHTTTLRAFGSSGGGCISEGYAYYTDSGPVFVKVNRRTQARQMFEGEMASLEALRNTGLVRVPKPMKVIDLPGGGAVFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKSKTRQNTVGCGAEGAEPQGVTKFGFHTVTCCGFIPQVNEWQEDWPTFFTRHRLQAQLDLIEKDYADRETQELWSRLQVKIPDLFAGIEIVPALLHGDLWSGNVAEDDQGPVIYDPASFYGHSEFELAIASMFGGFPRSFFTAYHRKIPKAPGFDKRLLLYQLFNYLNHWNHFGREYRSPSLGVMRKLLR
What is the function of this protein?
Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate (PubMed:11016445, PubMed:16819943).  Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions (By similarity).  Involved in intracellular deglycation in erythrocytes and pancreatic islets (PubMed:16819943, PubMed:20009024).  Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function (PubMed:31398338).  Also able to phosphorylate psicosamines and ribulosamines (By similarity).
What are the official names of this protein?
Fructosamine-3-kinase, Protein-psicosamine 3-kinase FN3K, Protein-ribulosamine 3-kinase FN3K.
What is the protein family that this protein belongs to?
Belongs to the fructosamine kinase family.
Protein: LEXA_BACC0
Sequence: MEKLTKRQQDILDFIKLKVQEKGYPPSVREIGQAVGLASSSTVHGHLSRLEEKGYIRRDPTKPRAIEILGEDRMDTETQSVIQVPIVGKVTAGLPITAVESVEEHFPLPASIVAGADQVFMLRISGDSMIEAGIFDGDLVVVRQQQSAYNGEIVVALTEDNEATVKRFYKEKDHFRLQPENSSLEPIILKQVSVIGKVIGVYRDLH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SWF1_KLULA
Sequence: MFLLFLLFVVSQVGLLVFSPKFKDLILFRWYYQHIYYPLFTDYTRYRWKYWLVPGFYACILIFCVHLFYNKLNDTVNPYLYSLEKAFIPITIAFTSLTGVASVFVKPLGLQAGPQFQPDYIIFHPSAVCQTCKTIKVPRSKHCPICERCIPLHDHHCIWINNCVGYGNYEYFYSFLLSNCLLLTYASLRLLTLFRITAFKKDKFFLSLFLLTTAFSLIAIVFTYYQLKLVNDGMTNNEQDKWYLVQEYMRNGNLVKDMDGVLYYRSMSTDAQTAEPIFYSTNLYDHSKYHLINPAKILSHEEIINLYDRGSFLDNLKERIHLLD
What is the function of this protein?
Palmitoyltransferase that targets several endosomal SNAREs.  Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain.  May have a role in the cellular quality control of transmembrane domain-containing proteins (By similarity).
What are the official names of this protein?
Palmitoyltransferase SWF1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TAILC_BPSK2
Sequence: MAIPKKLRLFTLYVDGTNHIGKIPSVTLPKVTRKTEDYQGGGMQGAVAVDLGLDGGALDASMVVGGVVEELILKYGGDIDEMRLRFVGEIYSGGTSSLMEVEMRGRITEIDPGEAKQGDDTNHTYAIKNTYYKLSVDDKALLEIDLLNFIYKRDGKNLYPDRIVSALGLGG
What is the function of this protein?
Forms the virus tail tube.
What are the official names of this protein?
Major tail tube protein, GpFII-like protein, Virion protein C.
What are the subcellular locations of this protein?
Virion.
Protein: CEAM7_HUMAN
Sequence: MGSPSACPYRVCIPWQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQNLYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGIYTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNVRYESVQASSPDLSAGTAVSIMIGVLAGMALI
What are the official names of this protein?
Carcinoembryonic antigen-related cell adhesion molecule 7, CEA cell adhesion molecule 7, Carcinoembryonic antigen CGM2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Apical cell membrane. Note=Localized to the apical glycocalyx surface.
Protein: TRMB_CRYNB
Sequence: MEAGPSTASPGVSVSPAPALTAGEVQLLKVPQKRFYRQRAHANVFIDHELDYPKRPELMDWSTHYPAYFSQPNEDGTITQGEKKVEWADVGCGFGGLLMALAPLFPEKLMLGMEIRTSVTKYVTDRIAATRQAQSLLPADSVDTKPGGYQNVSVIKANSMKHMPNFFAKGQLEKIFFLFPDPHFKNRKHKARIITPALLAEYAYVLRPGGILYTVTDVKDLHEWMAHHLHAHPLFEYIPTETLSDDPILEAARTATEEGQKVERNKGDKWVACFRRKEDPKEEDED
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL29_METAR
Sequence: MAILRAKEIRGMSDKELDKQLKDLRNDLLKQHAISATGGAPENPGRIRELRRTIARILTIKQEKKQKEMKR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GCY1_CAEEL
Sequence: MQIFTILLLFNIFPSIFVQNLPDTTVAPRTKRTIKIGIAAAQRIQTSSIGWSVCGGAVPLAIERLKEMGFVKDFDFEYIVDYTECDLGSVVRAGMEFIKTHKVDVIIGPPCAQALRLMSFLAENYKKPVLGWGFVSDTDLSDVIRFPHLTTVIPNSLMLGYAASKMLTTFHWNRVALLYYFSDVKYCSGVMNDIEATFNDPSTPNVNIVIKAEIYLNDNETTDNVFQTVKSRARIILWCTQTSVEKRDYLIKIATHDMIGDEYVHIMLSMRNVAFGTQTSLGKPTFSQSGLTPIWESFTEGTDGFEKMAKQAATRMFVLDVNSEVADKKYLEYMQKNIIKAVQSPPMNCSTVECMTANTTIMGGYARHLFDVVYLYGIALTHTNSTDPAVYGDVDVLVHQFVTSFQGMTGHVVISPNLTRMPIFQLYGLNSDYDQVALVDFTYTNSVMVPNVTLFYKDEGGAVWSYYGHSRPLDIPICGFLGKSCPVSFWEQYKILIFVAIAVIVLMVLIMIIGCLCVISGKRAERARINAEWQVPFAKLIESEKQVRGKGASRRSLQSAPSISTGHSGVTTVSDFCENYTMMMYEKEMVLTAKYQYTHLTKADKERFVKMRKLDHENINRFIGLSIDSAHFISVTKLCSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEYLHKTFLRLHGNLRSATCLVNDSWQVKLAEYGMDNLVEEQTPPKKRLLWVAPEVLRGSLSVSQMEPSADIYSFAIIASEILTKKEAWDILDRKEDCEEIVYNVKKGGLFPIRPEIITDIHDVNPALIALVKDCWAEVPEDRPTAENICSQMKGLVSKQKTNLMDHVFNMLEEYTSTLEEEIEERTKELTLEKKKADILLSRMLPKQVAERLKAGQTVEPEGFDSVTVFFSDVVKFTILASKCSPFQTVNLLNDLYSNFDTIIEQHGVYKVESIGDGYLCVSGLPTRNGYAHIKQIVDMSLKFMEYCKSFNIPHLPRENVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGKPSLIHLTNDAHSLLTTHYPNQYETSSRGEVIIKGKGVMETFWVHGRFGEMEPTELRSISNRSTPPVTNDRWIPNPSSSHGSRPSSVYDPLQGHQKFKMDTLKVAN
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).  Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron (PubMed:19523832).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-1.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: XNI_SHESM
Sequence: MNKFLIIDGLNLVRRIYAAIPDENDMDSLTDRVSVACTKLLRIHHPTHVAIVWDGDEISWRKQLYPDYKKGRKPMPEPLAAGLSALQEHLKSLPIQSIYAAAEADDVIATLAMKTAKAQGEAVIVSTDKGFSQLNHPRISQWDHFNQQYLNIAELEQKLGVDRNQFLDLMALAGDSGNKIPGIAGIGPKSAAELLRTFRTLATLFSSLSNLGAKQAKKLAEGRDMARLSYKLAQLQTDLPLNINLRDFRVNGPANTQQAE
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: FACE1_ORYSJ
Sequence: MALPYLEAVLCFMILMYIFETYLDIRQHRALKLPTLPKPLVGVISGEKFERSRAYSLDKSKFHFIHEAVTILMDTTILYYRVLPWVWKKSGELATNAGLNAENEILHTLAFLAGVMIWSQITDLPFSLYSTFVIEAKHGFNKQTIWLFIRDMIKGILLSILLGPPIVAAIIIIVQNGGPYLAIYLWGFMFALSLVMMTIYPIVIAPLFNKFTPLPEGVLREKIEKLAASLSFPLKKLFVVDGSTRSSHSNAYMYGFFKNKRIVLYDTLIQQCSSEDEIVSVIAHELGHWKLNHTVYSFVAVQLLMFLQFGGYTLVRNSKDLFESFGFEDQPVIIGLIIFQHTIIPVQHLLSFCLNLVSRAFEFQADAFAKNLGYAPQLRAALVKLQEENLSAMNTDPWYSAYHYSHPPLVERLSALEDADSKKEN
What is the function of this protein?
Proteolytically removes the C-terminal three residues of farnesylated proteins.
What are the official names of this protein?
CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HEMH_CHLCV
Sequence: MVSAYLLANFGGPRHSNDIEVFLTSLLTDRDVTGGFLPSFIHKRLFSFIAKKRALKVLPQYNCIGGFSPIYQDTELLAETLSSHLDAPVITFHRYLPDTHPHTIQQLKTLGDFPIVGVPLFPHFTYAVTGSIVRFIHNQLPLLNISWVSHFGNHPEFISCMMDHILKFLQSHDISTHDCCLLFSAHGLPMRHVNKGDPYNMQCEKSFRAISERLPNIETHLCYQSKFGPGKWLSPSTKDLCATLKTDKKHVLIVPFGFTSDHIETLYEIEKEYIAVLIDKGYQALRVPAIYQSSQWVESLATIIQSTPHVEKKSLIKS
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI_ECO45
Sequence: MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEEAVIRRCRYELGVEITPPESIYPDFRYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLAAVLRGIDATPWAFSPWMVMQATNREARKRLSAFTQLK
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_YERPN
Sequence: MILIEHILGNVKKDPVWREKLKDATFDLLILDQREAQKSRCRKSSTQGLDLGISLDRNVVLADGDVLAWDEETNVAVVVQINLRDVMVIDLSELKSRSPDELIKTCFELGHALGNQHWKAVTKHNEVYVPLTVATTMMDSVMRTHGFQHLPFRFVKGAEILPLLTNSEARLLFGGAEDTDTHVHVASPLDEPHGSGLHIHGIHSHEEGHSHGDHDHDHSHSHGDHDHDHKH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRTL_STRZT
Sequence: MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLDFNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLPNSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.