PharMolix/UniProtQA huggingface dataset:
Protein: POTA_NITEC
Sequence: MALLELRNVIRRFGDFTAVDNVSLSIQAGEFFTLLGPSGCGKTTLLRMIAGFDVPDSGQILLDGQDIANTPPEKRPIHTVFQSYALFPHMTVADNVAFPLKMSKVAPAEIKKRMEKALEEVQLSRFTHRFPHELSGGQKQRVAFARGLINRPRLLLMDEPLGALDAKLREDMQRELINLQKEVGITFIFVTHSQDEALALSQRIAVMNLGNIEQIGTPSAIYGTPANRFIADFIGKINLMEARVTQISNTAMTLEINGLGTTVLPPKKEIQAGDQGVIAIRPEQVAVHALAKQAEIPHAHTGKVLDFLYVGDVTTYVIELDSGIQIEALLANSSPGRARFFEVDDPVIVSWPQEAAQFLVDRP
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBP48_RAT
Sequence: MAPRLQLEKAAWRWAETVRPEEVSQEHIETAYRIWLEPCIRGVCRRNCRGNPNCLVGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGLTNLGASCYVNTFLQVWFLNLELRQALYLCPSTCSDYTKGDGIRGGKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLDTGQQQDAQESSKLFMSLLEDTLSKQKNPDVRNVVQQQFCGEYAYVTVCSQCGRESKLVSKFYELELNIQGHKQLTDCISEFLKEERLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNAYIGFSESLDMEPYVEHKGGSFVYELSAVLIHRGVSAYSGHYIAHVKDPQSGDWYKFNDEDIEKMEGKKLQLGIEEDLTEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKNHTMVQVPAFLQELVDRDNSKFEEWCVEMAEMRRQSVDKGRAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNNACLCSHDKLHPDKISIMKRISEYAADIFYSRYGGGPRLTVKALCKDCVVERCRILRLKNQLNEDYKTVNNLLKATMKGSDGFWVGKSSLRSWRQLALEQLDEQDGEAEQSNGKINGSPFSKDESKEEKKEEEEELNFNEDILCPHGELSISENERRLVSQEAWSKLQQYFPKAPEFPSYKECCSQCKILEREGEENEALHKMIAKEQKTSLPNLFQDKNRPCLSNWPEDTDALYIVSHFFLDEWRKFVRKPARSTPVSSVGNAALLCPHGGLMFTFPSLTKEDSKLIALIWPSEWQMIQKLFVVDKVIKITRIEVGDVNPSQTQYISEPNLCPDCREGLLCQQQKDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKPDGEKDPDFNQSNGGTKRQKTSQQGYVAYQKQVIRRSTRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILNDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH
What is the function of this protein?
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.  May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2.  May also play a regulatory role at postsynaptic sites.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 48, Deubiquitinating enzyme 48, Synaptic ubiquitin-specific protease, synUSP, Ubiquitin thioesterase 48, Ubiquitin-specific-processing protease 48.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In neuronal cells, it localizes to dendrites, as well as somas.
Protein: RL10E_SULIM
Sequence: MPLRPGRCYRHFSGPAYTRKEYIPGIPQPKITKFTSGNPNGDYDYEVRLITTEIGQIRHNALEAVRTITLKTLTKRTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGEILIVVKVKKEHLDFAKEALKIASKKLPLRTRIEIIPLRPIRQEVQS
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ACOD1_MOUSE
Sequence: MPAHMLQEISSSYTTTTTITAPPSGNEREKVKTVPLHLEEDIRPEMKEDIHDPTYQDEEGPPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSHKSS
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the Delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:11500518, PubMed:11533264, PubMed:16275639, PubMed:16443825, PubMed:26098370).  Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:11500518, PubMed:11533264, PubMed:16443825, PubMed:26098370).  Plays an important role in lipid biosynthesis (PubMed:17127673, PubMed:10899171, PubMed:11500518, PubMed:11441127, PubMed:11533264, PubMed:12177411, PubMed:26098370).  Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (PubMed:12177411, PubMed:17127673, PubMed:24356954, PubMed:24295027).  Plays an important role in body energy homeostasis (PubMed:17127673, PubMed:15210843, PubMed:24295027, PubMed:24356954).  Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (PubMed:10899171, PubMed:11500518, PubMed:11441127, PubMed:11533264, PubMed:12177411, PubMed:15210843, PubMed:26098370).  Required for normal development of sebaceous glands (PubMed:17738154, PubMed:11533264).  Required for the biosynthesis of normal levels of Delta-9 unsaturated fatty acids and 1-alkyl-2,3-diacylglycerol in the Harderian gland (PubMed:11500518).  Required for normal production of meibum, an oily material that prevents drying of the cornea (PubMed:11533264).
What are the official names of this protein?
Acyl-CoA desaturase 1, Delta(9)-desaturase 1, Delta-9 desaturase 1, Fatty acid desaturase 1, Stearoyl-CoA desaturase 1.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane.
Protein: CML37_ARATH
Sequence: MTLAKNQKSSLSRLYKKVSSKRSESSRNLEDESRTSSNSSGSSSLNVNELRTVFDYMDANSDGKISGEELQSCVSLLGGALSSREVEEVVKTSDVDGDGFIDFEEFLKLMEGEDGSDEERRKELKEAFGMYVMEGEEFITAASLRRTLSRLGESCTVDACKVMIRGFDQNDDGVLSFDEFVLMMR
What is the function of this protein?
Potential calcium sensor that binds calcium in vitro.
What are the official names of this protein?
Calcium-binding protein CML37, Calmodulin-like protein 37.
Protein: NAC10_ARATH
Sequence: MSWCDGSDDNYDLNLERVSNTDHPSVQLKDQSQSCVTSRPDSKISAETPITTCPSCGHKLHHHQDDQVGSIKDLPSLPAGVKFDPSDKEILMHLEAKVSSDKRKLHPLIDEFIPTLEGENGICYTHPEKLPGVSKDGQVRHFFHRPSKAYTTGTRKRRKVSTDEEGHETRWHKTGKTRPVLSQSGETGFKKILVLYTNYGRQKKPEKTNWVMHQYHLGSSEDEKDGEPVLSKVFYQTQPRQCGSMEPKPKNLVNLNRFSYENIQAGFGYEHGGKSEETTQVIRELVVREGDGSCSFLSFTCDASKGKESFMKNQ
What is the function of this protein?
Transcriptional activator that plays a regulatory role in the development of secondary cell wall fibers.  Is a direct target of SND1.
What are the official names of this protein?
NAC domain-containing protein 10, ANAC010, Protein SECONDARY WALL-ASSOCIATED NAC DOMAIN PROTEIN 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDK_XANC8
Sequence: MALERTLSIIKPDAVAKNVIGEIYSRFEKAGLKVVAAKYKQLSRREAEGFYAVHRERPFFNALVEFMISGPVMIQALEGENAVAAHRDLLGATNPKDAAPGTIRADFADSIDANAAHGSDSVENAANEVAYFFAATEVVSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_PSEPK
Sequence: MSTREIRIATRKSALALWQAEYVKARLEQAHTGLQVTLVPMVSRGDKLLDAPLAKIGGKGLFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTFDSLEALPAGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFEDRITSTISVDDSLPAGGQGAVGIECRSADVEIHALLAPLHHVDTADRVIAERALNKRLNGGCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRAAAEALGVQVAEDLLGQGAEAILKEVYGEAGHP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ACYP_RHOPA
Sequence: MSEIIRQVMISGRVQGVGYRAWLAHTAEAMGLHGWVRNRRDGSVEAVLAGSEPIVSEMIARCQRGPSAARVEAVVAEIAQPDVLNLRQPGERFSILSTL
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: Y256_MYCPN
Sequence: MDRKIVQLIHNFSGTEKLKAAVFSHDEQCFFDFVSFDELNSKLTGFLLFDSLEKLFKLVETIQQKRSWLYVDELWLINTATENQQLNEVSVWLVKKELAQVGVLTQLDTSLVKLLMASKNTDSALYNTYIKPVELQQFTQTPAPDNVNAEQSHLTLESTTDLNNSQLANTPALWEVEQTTQELLPTMDFSKFIDELDQITKNFSDLELEPLSFNEGFDEWNQE
What are the official names of this protein?
Uncharacterized protein MG117 homolog.
Protein: ERC6L_DANRE
Sequence: MESNNVEEVTDKFGGCLSLDTEKMGKYDRYRQKGKEAALNGELPRALELFQLAYQLQPSEKLKKRIQAIQDLIQREDEEDEEEEEEFVNVNNSGLKLYKGLYDKLYDHQKEGVAFLYSLYRDGRKGGILADDMGLGKTIQVISFLSGMYDAELANHTLLVMPTSLIKNWVREFAKWTPGMRVKEFHGSSKTERNRNLERIQRKGGVIITTYQMLINNYEQLGSNGHREFKWDYVILDEAHKIKTSSTKTAKSAHAIPAKNRVLLTGTPVQNNLREMWALFDFACQGSLLGTSKTFKTEYENPITRAREKDATPGEKALGLRISQNLTDIIKPYFLRRTKADVQQKKLKLEEGFEEEEDQENKCPNAREGVEMPSLTRKNDLIVWTYLSSVQEDIYNKFISLDQIKELLTTTRSPLAELTVLKKLCDHPRLLSQRAVIQLGLERGSDSELVHSDESESAVSQIDNISDHTLIEESGKLQFVVSLMECLREEGHRTLIFSQSRKMLDIMERVLRNRNFRLLRLDGTVTQLAEREKRISLFQTDKRYTIFLLTTQVGGVGITLTGANRVVIFDPSWNPATDAQAVDRAYRIGQTENVIIYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYFSKQELRELFKLEDTRSSSTQQQLQAMHAQSRRSDTSLDHHIARLHSMEMFGISDHDLMFTKEPAADEDDPEDAESHHYIQTRVQKAQELMQAESELHGQLLDSMAQNTEPAWLRQMGQPNSSIRDRPAPPRIKNEPVTVDLTHNSFDEPEFEEDEQNLPSAEDAEMETASEDVEVIGDEDLGDKVISSEVEVVGEEVEVVAEEVEDAGEVEVVSEEVEGVGVEVEDVGVEVEDAGVEVEDAGVEVEDAGVEVEDAGEVEVVSGEGQVQPKSPQSGGEWNLQIVKTEVSPIAEKFADVITLDDTSDEADSSDFNTESKQQNSSQRFQSPSLQFPKLDDLSGASNTLGNEEVEPEKCHSQVLSSPLSQHEATTDEPFKAEMEMPHGNFNLLLEDSADMYFPEDEEVHEVEESAAEESPEFQLQMDVSGERLEEPSINHDKQNNGEFVNYNDSEVSKRESLLKIRSTPNESVDDSFVHSVRTKKRQVISDTEEEEEEEEESEKPCLTSSPFIDAISRLGSSTPKAVLVDGARLRRSLNASVASRRSFVVSLLENESDEESNEDKTKSSGASETCADELVEEVQTSSGDNSKSYETSEANGTLADELVEEEGEYREGKNTSDKVSESNETHSEEFAEEEKPSGDKSESYEISEASETHTDNSEEEIIGDHTGSYKISESSEADESVVEEEEPSGETLNTEESEMGEEEESAELIAGQEQEEWHSAVLESTGDVELDSNETMDQCAPKTVPVETHVLPVSSTNTAAEASDNKYNLLVLSGKQSLAEGRKQEALDFFLKAIDINTGDPEIQLLIIQLYRQLSQ
What is the function of this protein?
DNA helicase that acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.  Functions as ATP-dependent DNA translocase.  Can promote Holliday junction branch migration (in vitro).
What are the official names of this protein?
DNA excision repair protein ERCC-6-like, ATP-dependent helicase ERCC6-like.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Chromosome, centromere. Chromosome, centromere, kinetochore. Chromosome. Note=Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase.
Protein: COAX_ALKOO
Sequence: MILVFDVGNTNIVLGVYRGKELIENWRIATDKDKSSDEYAMVIHQFFHYNGLNIHDVDDVIISSVVPNIMYSLENASRKLFKREPLIVGSGIKTGMNIKYDDPKQVGADRIVNAIAAYEKYGGPLIIVDFGTATTFCAVSEDGEYLGGAISPGIKISSEALFEKAAKLPRVELINPKKVICKNTVSSMQAGIVYGYIGLVENIVRNMKKELKSSSCKVIATGGLSTLIAGGTDSIDVVDKFLSLDGLNIIYERNRKDRILSNKKS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIS1_YEASV
Sequence: MSLISAVEDRDIHNIGKTSGGGSRTSSITSSKKSLKHGSKSLRKPKVYQTTGELLSREALYKAKLKYGVYQSPAQSYSIGVSDAHAASDKAANLAHDNQTTVEAYKRMFIDPNATKAASKMGPKVVRNNSITSATSKTSXESQTKRKSKESPGAAASKAYSMTMETTSLSSQTNSRSYSITSASSVLSGASGSFNSTVNPKPKTLNLEKVLVGAEKKAESRIKERWEPEKTNFQYGVKTDEHGNLNQFSFSNEMMNNIMAKVDAPKAQDLQKVKKVSAEKEAKSMKFALGAANAVKDMHPGEDIDKSIALKAQKRETYLSQLTSQQVLTLARANVDRQLDIIEKSDMHRKLFTNMEYNKAAVAVAQSNHQKKTEFHNKINMGGGLFLSPEDITKIASGLISPVLGEVSERAEAQRAMDEEIAERTEAYNKSLNEWETMERSIISNDAKVLTTTANRHQTEKKTSQEKIKASFDALVARMDTKVAERETLLEDTKSKEIEFKKQMQQELKDEKARLDQDLEEWGKKCEQDITEARKEQEELLKPYHDDLANAEAEHKTLVEERDXINAEISRLQDAIVDHKRKISGYGNDLDAQKNRNIREDDKLLELGQTKESLESHLNDDVIILANKAKEQAELSTKEARLKQLEVDSLINERKSELNATXIELKKEKLXLLEAMKDVASARGDDKIDEEKVKKLIGMTSEEYLTQNKSVEKNVEDLPTQLEXIEEGDELKKEEIVGAETKNSGGDGVPVSTAAKEATETSSAVQTKEPEEKISIGNKSSGKEDANDCKSAEHSKEISVSQKAGNNKSLGVSPDSLEHTFSGFSQGSSIEDDQDAISNQEKK
What is the function of this protein?
Required for normal formation of eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on plasma membrane and mark the site of endocytosis.
What are the official names of this protein?
Eisosome protein 1.
What is the protein family that this protein belongs to?
Belongs to the EIS1 family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes at the eisosomes.
Protein: RPIA_BARHE
Sequence: MNVQQLKKMAALKALEFVEDDMRLGIGSGSTVNEFIPLLGERVANGLRVTCVATSQYSEQLCHKFGVPISTLEKIPELDLDIDGADEIGPEMTLIKGGGGALLHEKIVASASRAMFVIADETKMVKTLGAFALPIEVNPFGIHATRIAIEKAADNLGLSGEITLRMNGDDPFKTDGGHFIFDAFWGRILQPKLLSEALLAIPGVVEHGLFLGLASRAIVAMADSQIKVLEPFDF
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: AB17C_BOVIN
Sequence: MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQRGPGAPAPASAASTSSASAAAQPAPQQPEEGGAGPGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins.  Has depalmitoylating activity towards NRAS and DLG4/PSD95.
What are the official names of this protein?
Alpha/beta hydrolase domain-containing protein 17C, Abhydrolase domain-containing protein 17C.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD17 family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: ATPB_ECO7I
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: 3BHS3_MESAU
Sequence: MPAWSCLVTGAGGFLGQRIIRMLAQEKELQEVRTLFRSFTPKHREELSKLQTKTKVTVLEGDILDAQCLRRACQGISVVIHTAAAIDVFGAIPRQTVIDINLKGTQHLLDACIGARVPVFIYSSSVAVAGPNSYKVIIQNGSEEENHESTWSDPYAYSKKMAEKAVLAANGSTLKDGGTLHTCALRLPFIYGEKSKFISDTMDRALKNNGLINGFSRFSVISSVYVNNAAWAHVLAARGLQDPKKSPNIQGQFYYISDDTPHQSYDDLCYTLSKDWGLRPDSSWKPPVALLYWFGFLLETVSFLLRPVYNYQPPFNRHLVTLLNSVFTFSYKKAQRDLGYEPLVSWEEAREKTSEWIGSLVEQHKGTLNIKAQ
What is the function of this protein?
Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids.  Catalyzes the conversion of dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR.  Does not function as an isomerase.
What are the official names of this protein?
NADPH-dependent 3-keto-steroid reductase HSD3B3, 3 beta-hydroxysteroid dehydrogenase type 3, 3 beta-hydroxysteroid dehydrogenase type III, 3 beta-HSD III, Dihydrotestosterone 3-ketoreductase.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: PDXH_BRUA4
Sequence: MTNASDDFTESSQPFKLFADWLTDAKASEPNDPNAVALATVDPDGLPNVRMVLLKDFDEQGFVFYTNYESTKGKEILSAEKAAMCFHWKTLRRQVRVRGAVEKVSDAEADAYYASRPRGSRIGAWASKQSRPLESRFALEKAVAEYTAKYAIGDIPRPSYWSGFRIRPVSIEFWHDRAFRLHDRVLFTRPAPEGDWNKERLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: MSHC_COREF
Sequence: MHSWPTPDIPALDGTPVPLALYDTADQQVKPVEVPPSGSGTPVGMYVCGITPYDSTHLGHAATYLAFDLIYRVLLDNDHQVHYVQNITDVDDPLFERAERDGVDWRELGTSQIDLFRKDMETLAVIPPKDYIGAIESIDEVIEMVSTLLEEGAAYVVDDPEYPDVYASINATENFGYESNYDAATMAELFAERGGDPDRPGKRNPMDALLWRAAREGEPSWESPFGPGRPGWHIECSAIATNRLGHSFDIQGGGSDLMFPHHEFSAAHAEAAHGVERMAKHYVHAGMISQDGVKMSKSLGNLEFVHRLTAAGHEPGAIRLGVYAHHYRGDRDWSDEILAAAEARLALWRSAITVATDVQAAVDAVAQLRTHLSNDLDTPAALAAVDAWAEAALKDTGNVSDTADQFDTPEFTPAGRILAAAVDALLGVRL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: RS11_THENN
Sequence: MARKKGTSTRKKQKKLSFDYGVVHIKSTFNNTIITLTDKDGNTLTWASGGTVGFEGTRKGTPYAAQLAADKVAREALRMGIKRVDVLVKGPGPGREPAIRTLQGAGLEINQIKDVTPIPFNGCRPKKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GSA_METLZ
Sequence: MKSEELFTTAKTCLPGGVSSPVRAIKPYPFYVKSARGATLETEDGESLVDCCMGYGPLLLGHAHPAIQKAIEAQLDAGWLYGTPTKLEIDLAQRICRDHPSIEMLRCVSTGLEATLAAIRLARGFTGKCGIVKLEGGFHGAHDAVLIAAGSGATTHGTPDSLGVPPSFAAQTRQVPYNDPEALEELLSKDKEIAAFILEPVMGNVGPVLPDDGYLSAVREITKAHDVLLIFDEVITGYRVGIGGAQKKYGIKPDLTTLGKITGGGLPIGVFGGRRDIMELVSPSGGVYNAGTFNGNPLSMAAGIATNVYLHENESLYAELDEKTRAIEESLPAKASGSFVRLGSLFKYFFRSTAPRNYLEAKESDTAAFRVFFEKALKDGVFIPPSQFETNFLSTAHDASSMEKIISVYQHV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1053_BACHK
Sequence: MVHMHITAWALGLILFFVAYSLYSAGRKGKGVHMGLRLMYIIIIVTGFMLYMGIMKTATSNMHMWYGLKMIAGILVIGGMEMVLVKMSKNKATGAVWGLFIVALVAVFYLGLKLPIGWQVF
What are the official names of this protein?
UPF0344 protein BT9727_1053.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL36_STRT2
Sequence: MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: COX7C_SAISC
Sequence: MLGQSIRRFTTSAVRRSHYEEGPGKNLPFSVENKWRLLAMMCLYFGSAFATPFLILRHQLLKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7C, mitochondrial, Cytochrome c oxidase polypeptide VIIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIc family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: CCA_MANSM
Sequence: MQTYLVGGAVRDQLLNLPVKDRDWVVVGATPEQLLSLGYQQVGRDFPVFLHPKTKEEYALARTERKSGAGYTGFICDFSPHISLEQDLIRRDLTINAIAQDNQGKFIDPYEGISDLKNRTLRHISPAFAEDPLRVLRVARFAARYHQLDFSIAPETIALMAEITEKGELQQLTIERVWQETEKALKEKNPEIYFQVLLQVGALKILFPELYALYGVPNPAQYHPEIDSFLHTMLVLQQAVRLTENTEFNKSAVRFAAICHDLGKALTPKDILPHHYGHEKAGIQPIRTLSNRLKVPTYYKELAEFTCEYHSYIHKAFELKPETVIKLFNKLDVWRKPQRFEELMLVCVADTRGRTGFEQTAYPQKDYLRQLYQTALQVNVQQVIEDGFEKQGIRDELTRRRTIAVKTKKAEILPRFVGQ
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.