PharMolix/UniProtQA huggingface dataset:
Protein: EMT1_PSEA3
Sequence: MKIALLANPARGEINVLLATAYELIRLGHEVVFLTGSSFRNAIAEFKDEQNDKLLASRIQFSDLGTAKAFEDFTRGMQSHLKGLRKPPGDYSSMEICQIVALVTEQEFREAATLVRDRLLELDPDMIAVDALSPNLVTGCRMTGLPWMFTVPCSPSLTATRKSLFDPHPMGSRRQRTLMSALENLKLTIRETYGNAIKKDLYARRALLKKEFGLNSMGFNADSAIVPPLWKDRNCVGGIHFNTPGLWDSIRQPHQITFVGCGVTSDPENHSPSQAGTPISEIAGWSPLTKLSTSFDQSGQGERDLDVEWMDAAYAAGESVVYLNMGSMFLWTDDEVRACLRAFERLHRESGGKIKLLFKLNKPKRNPGSPGFTSPLNSPTAVATPKWDEKRPIDSRRPSGVSTLIMAEKLSEAIKNVKPRRKTDAEKGYSQFMLSEFEGLEYVRFTRWVHDQRRIYKHPALRVVIHHGGGNSFNEAVHYGLPQMILSQWFDTHEYAILAERFGIGLRSKHAPFVDEQDMFAKMLRLLRGPEAEKIQANAKIWSTRSRNAGGAPAAARLLETHALLHRQRKQARDPTPTAKTSLSVDTTEVATPTFTDTETSLSPKILSSAASTVTNP
What is the function of this protein?
Glycosyltransferase; part of the gene cluster that mediates the biosynthesis of mannosylerythritol lipids (MELs), surface-active substances that enhance the availability of water-insoluble substrates (Probable) (PubMed:20564650, PubMed:31923270).  Depending on the number of acetyl groups, mannosylerythritol lipids can be differentiated into MEL A (fully acetylated), MEL B and MEL C (monoacetylated at R-6 and R-4, respectively), and the fully deacetylated MEL D (By similarity).  The first step in the pathway is the generation of mannosylerythritol by the glycosyltransferase EMT1 which catalyzes the transfer of GDP-mannose to the C-4 atom of meso-erythritol (PubMed:20564650).  This reaction has to be stereospecific, since only mannosyl-D-erythritol is generated (Probable).  The produced disaccharide is subsequently acylated with fatty acids of various lengths by the acyltransferases MAC1 and MAC2 at positions C-2 and C-3, repectively (Probable).  The existence of MEL derivatives which carry an acetyl group at C-2 implies that at least MAC1 also accepts acetyl-CoA as a donor (Probable).  The final step of MEL biosynthesis is the acetylation of the fully acylated mannosylerythritol lipids catalyzed by the acetyl-CoA-dependent acetyltransferase MAT1 (Probable).  MAT1 displays a relaxed regioselectivity and is able to transfer acetylgroups to both positions C-4 and C-6 of the mannosyl moiety (Probable).
What are the official names of this protein?
Erythritol-mannosyl-transferase 1, Mannosylerythritol lipids (MELs) biosynthesis cluster protein EMT1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: CYB_MOGTO
Sequence: MTNIRKTHPLMKIVNNSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVLLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDMDKIPFHPYYTIKDILGALVLILALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILVLALMPLLHTSKQRSMMFRPISQCLFWLLVADLLILTWIGGQPVEHPFIMIGQLASILYFSLILILMPLASLAENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRD_VEREI
Sequence: MPLLPYALTRPFLFGLDAEAAHELIIDLLARGQRTPLQWAWCNQTVDDPIELAGLRFPNRVGLAAGLDKNARCIDALGAMGFGFVEAGTVTPQAQPGNPRPRMFRLPEARALINRLGFNNAGLQAFVHNLQQSRLRAAGSALRLGLNIGKNASTPMAQASSDYLACLEGVYPHADYVALNISSPNTQNLRTLQGDAALDHLLGAIAERRATLAARHGRRVPVFVKIAPDLDEAQLSLMAATLQRHGIDGVIATNTTIDRAVVQGQRHAQESGGLSGAPVLQASNQVIGQLRAALGKGFPIIGVGGIMSAEDAVSKIRAGADLVQIYTGLIYEGPALVVQAARAIKAMGGCGPVIALPNRS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ISPH_PROMP
Sequence: MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLITSIRNNSFTYKKGRLNIKLAQAFGFCWGVERAVAMAYETRRHYPDENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKDFSLVSDGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWVSKVWHTVEKHKKHTFTSIIHGKFKHEETLATSSFADKYLVVLNLEEANYVSEYILGRGNKNHFLNKFAQAFSNGFDPDKDLDRVGVANQTTMLKSETEEIGKVFEKTMLHKFGPEKLNSHFLAFNTICDATEERQDAMFSLVDEDLDILVVIGGYNSSNTTHLQEIAINKNISSFHIDTPERISVKENSILHKPLKSEMVLKKNFIPDGEIKVGITSGASTPDKIVADVIEKLIAITK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: CMOA_SALPB
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNTQVYDLGCSLGAATLSVRRNIRHEHCRIIAVDNSPAMIERCRRHIDAYKAPTPVEVVEGDIRDITIENASMVVLNFTLQFLEPAERQALLDKIYLGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKSRLRKAGFEHSELWFQCFNFGSLVALKAGVAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RR16_LIRTU
Sequence: MVKLRLKRCGRKQRAIYRIVAIDVRSRREGRDLRKVGFYDPIKNQTYSNVPAILYFLEKGAQPTGTVHDISKKAEVFKELRINQTK
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SID4_SCHPO
Sequence: MDEAFGDSLSTDYRWLGHSHFDSHPSAGDSIYFDSLDEDADPSRTARIDRIAELLDGLNDEQISELVNGVNSTTIKENTKKEISNPNDSTRLPLEQIPGSNNLFLDPRHQLGDNSQNAQRHHEPSFNSEKASYTSTPYKNVAPKVIDSPSARHMHSNSPSFPPSQSHTSSYDQSPKGQLRDNISVPNQQDGLDPEVFNQQSKETKKSLQVPPSRNVPPPVTRPNQYNPEPNFSLSSGYPQQHFSQPELQNRNVHLETVPESYPVPPSGYPLTSSTCVSSISQPIQSTDCQKAQENLSNNKQMSSNDQDIDPFKQAITDLPPSFVNIVLEMNATIQSLSNQCQQRDKQIENITKQLLMNQQDYCPTTMSTTVSTPLCPPKRFPKSTKDFKEQKPDTKQVRSATISNDFNLKGNGRYNEKSQIAVPSEIRVQLSTLDAILLQFEHLRKELTQARKEIQILRHTSQNGDQESNESSKNAITTKTTDKGNNKENTMLNDGSTAPAKNDIRNVINTNNLDAKLSDESELMIEKNKSYSTPASSTIPTFHTSQPLTSLNMPDSRFNLAKEKQLYYRLGLQHIDQQCSVETANMLKTVLVQLNIPFAIFPSTIGQVRRQLQQGRRLYQWARNIHYLIYEENMRDGLVSKQCLADMLKKIRELKKRSL
What is the function of this protein?
Required for activation of the spg1 GTPase signaling cascade which leads to the initiation of septation and the subsequent termination of mitosis.  May act as a scaffold at the spindle pole body to which other components of the spg1 signaling cascade attach.
What are the official names of this protein?
Septation initiation protein sid4.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: RS18_DROME
Sequence: MSLVIPEKFQHILRIMNTNIDGKRKVGIAMTAIKGVGRRYSNIVLKKADVDLTKRAGECTEEEVDKVVTIISNPLQYKVPNWFLNRQKDIIDGKYWQLTSSNLDSKLRDDLERLKKIRSHRGLRHYWGLRVRGQHTKTTGRRGRTVGVSKKK
What is the function of this protein?
Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
What are the official names of this protein?
40S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5656_ARATH
Sequence: MASEKSTSKGQAWFCTTGLPSDIEIEVDDMTFHLHKFPLMSKSRKLHRLITEQETRSSSSMALITVIDPKVEETDKKGKGHEIEDDKEEEEVEEQEIEENGYPHIKLEDFPGSSESFEMVAKFCYGVKMDLSASTVVPLRCAAEHLEMTEEYSPDNLISKTERFLSHSVYKSLRESIKALKACESVSPLAGSLGITEQCIDSIVSRASSADPSLFGWPVNDGGGRGNISATDLQLIPGGAAKSRKKPSRDSNMELWFEDLTQLSLPIFKTVILSMRSGDLSSDIIESCLICYAKKHIPGILRSNRKPPSSSSTAVSENEQRELLETITSNLPLDKSSISSTTRFLFGLLRTAIILNAAEICRDLLERKIGSQLERATLDDLLVPSYSYLNETLYDVDLVERILGHFLDTLEQSNTAIVEVDGKSPSLMLVGKLIDGFLAEIASDANLKSDKFYNLAISLPDQARLYDDGLYRAVDVYLKAHPWVSEAEREKICGVMDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAQSPSTSQSTEPRPSAAIRNLTITEEDGDEAEGERQVDAGKWKKTVRENQVLRLDMDTMRTRVHRLERECSNMKKVIAKIDKEGSSPATTTDRPRSWSITKKFGCKFKTQVCDSHEATMVDHRSRRS
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At5g66560.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
Protein: AI1_USTMA
Sequence: MEKERIELRLDYVLNSGKKTGKSYESILKLIAETFGVQLTTTIHNRNISYYLIAITSPAKLAILINYLNEYSLFTSKYLNFQDFSNCVNMMLNKEHLTISGREKITILKESMNNKRTYGII
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded DNA endonuclease aI1.
What is the protein family that this protein belongs to?
Belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LPXB_XANOM
Sequence: MTGIGNQTSGIETGVHDRAPADGEPTALPISHSPLPIPGAHARPPRFALIAGEASGDILGAGLIAQLRLRYPNAEFVGIGGDAMRGAGCQTWFDASELAVMGLTEVLRHLPRLLKLRSAFRERVLAWKPDVFIGIDAPDFNLPVERWLKQRGIKTVHYVSPSVWAWREKRAEKIAVSADLVLCLFPMEPPIYAKHGVDARFVGHPMADDIAYQADRDAARATLGLSASSTVLAVLPGSRHGEISRLGDTFLQAAWLVCEHIPNLHVLVPAANAGCKQLLAEQLSRSSLPVMRSHLINGQARTAMLAADVVLLASGTATLEAMLVKRPMVVGYKVAPLTYRIVKLLGLIKVNRYALPNILANDDLAPELMQDDCMPERLCVALLDWLKHPAKVAALQPRYLALHAALRRDASARAAEAVAGLLQGRDWSGANI
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: DLTC_STRPI
Sequence: MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVEIENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT5G1_HUMAN
Sequence: MQTAGALFISPALIRCCTRGLIRPVSASFLNSPVNSSKQPSYSNFPLQVARREFQTSVVSRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
What are the official names of this protein?
ATP synthase F(0) complex subunit C1, mitochondrial, ATP synthase lipid-binding protein, ATP synthase membrane subunit c locus 1, ATP synthase proteolipid P1, ATP synthase proton-transporting mitochondrial F(0) complex subunit C1, ATPase protein 9, ATPase subunit c.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
Protein: EX7L_LYSSC
Sequence: MSSASYLTVKALTKYIKRKFDADPHLREVYVKGELSNVKIHQSGHIYFTLKDDGARIAATMFKAAATKLAFEPKEGMQVFIRGDVNVYEGYGTYQLYVQEMQPDGIGSLFVAFNQLKEQLQKEGLFKLDWKQSIPKFPEKIGVLTSTTGAAIRDICTTLKRRYPLAEILIYPTLVQGAQAAPNIVQNIQRANQDATCQVLIVGRGGGSIEDLWAFNEEIVARAIFESRIPIISAVGHETDTTIADYVSDLRAPTPTAAAEMAVPDQMELFQRVLSQKSQIHQMVRSQLMAERQRLNKLQQSYPLSMPERLYRPFTERLAQLESGLQTAMQVDLMKKSAQLQQLHSTVAQHSPKKALAFHQRELEARMQQLTRAATYYVAKQQQQFEATIRTLEALNPLSILTRGFTVAYKDQHMIKSSTEVQEQDYLTLAFHDGKVVAEVKDILPKNEGESL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCPP_ECOLC
Sequence: MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQPFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSATLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVILALSPFHNAVYQAL
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: HA17_MOUSE
Sequence: MALTMLLLLVAAALTLIETRAGQHSLQYFHTAVSRPGLGEPWFISVGYVDDTQFVRFDSDAENPRMEPRARWMEQEGPEYWERETQIAKGHEQSFRGSLRTAQSYYNQSKGGSHTLQWMYGCDMGSDGRLLRGYLQFAYEGRDYIALNEDLKTWTAVDMAAQITRRKWEQAGIAEKDQAYLEGTCMQSLRRYLQLGKETLLRTDPPKAHVTHHPRSYGAVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVNHEGLPEPLTLRWGRWEPPPYTVSNMATIAVVVDLGAVAIIGAVVAFVMNRR
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
H-2 class I histocompatibility antigen, Q7 alpha chain, QA-2 antigen.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: FAHD1_BOVIN
Sequence: MAASRPLSRFWEWGKNIVCVGRNYADHVREMQSAAPSEPVLFLKPSTAYAPEGSPVLVPAYTRNLHHELELAVVMGKRCRAVSEAAAMDYVAGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAFVPKEKIPDPHNLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIMTLEEGDIILTGTPKGVGPVKENDEIQAGIHGVLSMKFKVERPEY
What is the function of this protein?
Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro.  Also has oxaloacetate decarboxylase activity.
What are the official names of this protein?
Acylpyruvase FAHD1, mitochondrial, Fumarylacetoacetate hydrolase domain-containing protein 1, Oxaloacetate decarboxylase, OAA decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol.
Protein: YR849_MIMIV
Sequence: MKRALYLNKQYIPWGILNHKTLKNETVVLEKYNEINSSIGPVFHCKNLFVDSCDKDFVYFFVNKKFFPNVKKLYLASNPCSPEVLWRDFDTIYLTEIFSHYKNQWANNYKNVKIIPNNKFFYELQDYAPERIILEKEHDLY
What are the official names of this protein?
Uncharacterized protein R849.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L163/R849 family.
Protein: YEGX_ECO57
Sequence: MQLRITSRKKLTALLCALGLISIVAIYPRQTVNFFYSTAVQITDYIHFYGYRPVKSFAIHIPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKATEGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVLDVEERGKLSAKELRKRVSQWLKMVEKSTGKKPVIYSGAVFYHTNLAGYFNEYPWWVAHYYQRRPDNDGMAWRFWQHSDRGQVDGINGSVDFNVFNGTEEELQAFVDGIKETP
What are the official names of this protein?
Uncharacterized protein YegX.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
Protein: DCUP_CAMJJ
Sequence: MIFIDACFKKPTPYTPIWMMRQAGRYLPEYMEVRKQAGDFLSLCKDYKKASEVSLQPIDILDVDAAIIFSDILVVPLEMGMNLRFEKGEGPIFDNPISTLEDLEKLDDQNAHKKLNYVYDALKLTREKLSQNKALIGFCGSPWTIATYMIEGSGSKNYAKCKKMLYQNPELLHKILNKLTQVLKLYLEEQIKAGANAIQIFDSWASALEYDKFFEFSFNYMLEISNFIKSKYPNIPVILFPKGISGYLDRIDGNFDVFGVDWSTPLDLARDKLSHKYTLQGNMEPCRLYDKNAIKEGVEKILKTMQNKAHIFNLGHGILPDIPVENAKYFIKLVQESSAK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_MARMM
Sequence: MAIEPRAGILDIRPYKPGSSEAPGIENPVKLSSNENALGCSDKAAAAMTATASKLHLYPDGGATKLREAIAEAEGLEAENIVCGTGSDELLQLLGRAYLNPGDKVVQSQYGFLVYRLVAMQCGANLVSAPERDYRSDVDAILEAAGDDTRIVFLANPNNPTGTYISAAEVRRLRDGLPASTLLVLDAAYAEFVDNPDYEAGIELARERDDVIVTRTFSKIHGLAALRLGWAYGNKAIIDVLHRVRGPFNVNMAAIEAGTAAIQDRDFMKRSVEHNEEWVAFLRQQIGGLGLEVTPSVCNFVLIHFPETPGKTAADADAYLTSQGLIIRAVDPYGLPNALRATVGSETENRRLVDALSTFMKA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RL22_RHORT
Sequence: MGKQATERRLADTEARAITKMIRTSPYKLNLVAESIRGKTAERALAELTFSKRRMADTVKKTLQSAIANAENNHQLDVDQLIVSEAYVGKAMVLKRWRARARGRVGKILKPFSNLTIVVRERGETA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RPO3_PYRCJ
Sequence: MPKVSIVEKSQFFAKAVVEGVPPSLINSLRRVIISELPVLAIDSVVVVNNTSVMYDEMLAHRLGLIPLTTPLKDLPPIEDCESGLVDPSECTVRLTLQVNATGDVVVYAGDLVADRPDVAPVYKDIPIVKLVEGQSVVVEAYAKLGRARDHAKWQAALASYYYYPKVVVKREECREMCKEVCRNLENPLECTFNKATTCKEMCGGGIVVEWEKDKYVFWIESFGNYDAETALREAFRILKKKFEDFLDALSRKAEAKL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo3, DNA-directed RNA polymerase subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_TREDE
Sequence: MTKTKGKVVGINGNMISVSFEGLVTLNEVGYVEVGSKKLKSEVIRIRGEVAQLQVFEITKGIKVGDIVEFTGDLLSVELGPGLLGQVYDGLQNPLPELAEQAGYFLERGIYLNALSRTAKWHFTPSAKEGDTLKRADLLGTVPEGSFTHRIMIPFNMYGTYKLKSIKPEGDYTVDDTIAEVTDERGNVIPLTMSFKWPVKRAIDCYAERLKPTETLVTKMRTMDTFFPVAKGGTYCIPGPFGAGKTVLQHATSRNADVDIVIIAACGERAGEVVETLTEFPELKDPKTGRTLMERTIIICNTSSMPVAAREASVYTGVTLAEYYRQMGLDVLLLADSTSRWAQALREMSGRLEEIPGEEAFPAYLESYIAAFYERAGIVRLSDGSKGSVTIGGTVSPAGGNFEEPVTQATLKVVGAFHGLSRERSDARKYPAIHPLDSWSKYPSVLPLEQVKYGRSFLRRGTEVEQMMKVVGEEGTSIEDFIIYLKGDLLDAVYLQQNSFDKVDDAVSVERQQHIYNILIEILGTSFKFVSKDEARSYFSKLKLMFIDYNYSPWGSDAFKSHEDGIKKHIAEKADSLDERAKKLLKQAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: STT3B_ARATH
Sequence: MGGKSEPAKSESMATKPDLLNTSFFSFKSLKLKTKQQELLLRISILGLVYILAFIARLFSVLRYESMIHEFDPYFNYRTTLFLTEKGFYEFWNWFDSESWYPLGRIIGGTLYPGLMVTAALIYWTLRFLRFFVHIREVCVLTAPFFASNTTLVAYFFGKELWDTGAGLVAAVLIAICPGYISRSVAGSYDNEAVAIFALLLTFYLFVKAVNTGSLAWALASAFGYFYMVSAWGGYVFIINLVPLYVLVLLITGRYSMRLYIAYNCMYILGMLLAMQIRFVGFQHVQSGEHMGAMGVFLLMQVFYFLDWVKYQLNDTKLFQTFLRITVTSAILVGGVAVGVGTASGYISPWTGRFYSLLDPTYAKDHIPIIASVSEHQPTAWSSFMFDYHILLFLFPAGLYFCFKRLTDATIFIVMYGLTSLYFAGVMVRLILVATPAVCLISAIAVSATIKNLTSLLRTKQKVSQTGSTKGAGSSKASSKVTLDQSQPFQKNGAIALLVGVFYLLSRYAIHCTWVTAEAYSSPSIVLAARGAHGNRIIFDDYREAYYWLRQNTATDAKIMSWWDYGYQITAMGNRTVIVDNNTWNNTHIATVGRAMSSYEDDAYDIMRSLDVNYVLVVFGGVTGYSSDDINKFLWMVRIGGGVFPVIKEPDYLVNGEFRVDKGASPKMLNCLMYKLCYYRFGELTTEYGKPPGYDRARGVEIGNKDIKLEHLEEAYTTSNWIVRIYRVKPPTNRL
What is the function of this protein?
Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.  This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B, Oligosaccharyl transferase subunit STT3B, STT3-B, Protein STAUROSPORIN AND TEMPERATURE SENSITIVE 3-LIKE B.
What is the protein family that this protein belongs to?
Belongs to the STT3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PANC_BACAH
Sequence: MKIVTTVQEMQHITKELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDENVAKENGVDYLFYPSVEEMYPVEQTTTVEVVKRTDVLCGKQRPGHFAGVATVLMKLFNITLPTHAYFGMKDAQQVAVIEGFVADFNIPVTIVPVDIVREEDGLAKSSRNVYLSQEERKEAPHLYRSLCMAKERIEAGERNAEIITTLVKEYIETYTKGTVDYADLYAYPSLQVVDQIEGRIILAIAVKFENVRLIDNITLTVK
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.