PharMolix/UniProtQA huggingface dataset:
Protein: MAP1_PONAB
Sequence: MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDIAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMSQF
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 1, MAP 1, MetAP 1, Peptidase M 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_HAMD5
Sequence: MLKIFNTFNRKKELFTPIHPNTVGMYVCGVTIYDLCHIGHARTFVVFDVVARYLRYLGYSLTYVRNITDIDDKIIQRASQNHQSCEALTAQMLKEMYRDFDELNLLRPDLEPRATEHITEMITLTQQLLDQKYAYVAANGDVLFSVEKNPHYGLLSRQNLEQLQAGARVEVMESKHHPMDFVLWKMSKPNEPHWPSPWGEGRPGWHIECSAMNAKALGPHFDIHGGGADLMFPHHENEMAQSICAHKAPYVNCWMHSGMIMINKEKMSKSLNNFCTIRDLLQRYDPETLRYFLLSAHYRSPLNYTEENLKQARIALTRLYTALRDTNQKAFPEGGESFEKRFVSAMNDDFNTPEAYAVLFDTAREINKLKKEHPKAADGLAAQLRKMGKVLGLLESGSLLSLLNPEKDDRHQSAEIADLIEKRNLARAHKNWEEADNARTRLFEMGVVVEDTENGTNWRRR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_DESAH
Sequence: MPKIKTNRAAAKRFKKTGSGKYKFRKANASHILTKKTTKRKRSLRLDQIIGASDLKEVKRLLPNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: KUP_BRUME
Sequence: MSGELNGNDTSAQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYAFREALHAAATNGILARSDILGVVSLIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALVRGALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEGLEIVAPNLTPFVVPATVVILVTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSPAVAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGEAAALPFFQMIPSFALWPMVLLATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSEKLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAVTGNMLVTTVLLYIVMTRIWNWRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKTRKAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVVTASKPWVASADRARVSQYNERFMLVTLTFGYMQQPNIPRALGLCRRLGWKFDIMTTSFFLSRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTGRVVEIGTQVNI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAX1E_MESMA
Sequence: MKKISFLLLLAIVICSIGWTDGQFTDVRCSASSKCWPVCKKLFGTYKGKCKNSKCRCYS
What is the function of this protein?
Potent blocker of both large-conductance calcium-activated potassium channels (KCa1. 1/KCNMA1) and voltage-gated potassium channels (Kv1. 3/KCNA3 and ERG1/Kv11. 1/KCNH2).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 1.14, BmKcug1, Kcug1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPD_YERPE
Sequence: MSEFVTVARPYAKAAFDFAVEHQAVERWQNMLAFTAQVTRNEQIAELLSGAVAPETMSTTFIAVCGDQLDEPAQNFIRVMAENGRLLVLPEVLQQFIQLRASLESTVDVEVSSARALNDEQLAKIAAAMEKRLSRKVKLNCKIDKSVMAGVVIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPF_STAS1
Sequence: MTATTNMFVLGAAGTSGVQWGTIIVTLVTFLILLALLKKFAWGPLKDVMDKREHDINKDIDDAEQAKLNAQKLEEQNKQTLKETQDEVQKILEESKVQARKQHEEIIHEANIRANGMIETAQNEINSEKERAIADINNQVSELSVLIASKVLQKEISDKDQKALVEKYIKEAGDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FKB53_ARATH
Sequence: MGFWGLEVKPGKPQAYNPKNEQGKIHVTQATLGTGLSKEKSVIQCSIGDKAPIALCSLLPNKIECCPLNLEFDDDDEPVEFTVTGDRSIHLSGFLEYYQDDEDDYEHDEDDSDGIDVGESEEDDSCEYDSEEDEQLDEFEDFLDSNLERYRNAAAPKSGVIIEEIEDEEKPAKDNKAKQTKKKSQASEGENAKKQIVAIEGAHVPVLESEDEDEDGLPIPKGKSSEVENASGEKMVVDNDEQGSNKKRKAKAAEQDDGQESANKSKKKKNQKEKKKGENVLNEEAGQVQTGNVLKKQDISQISSNTKAQDGTANNAMSESSKTPDKSAEKKTKNKKKKKPSDEAAEISGTVEKQTPADSKSSQVRTYPNGLIVEELSMGKPNGKRADPGKTVSVRYIGKLQKNGKIFDSNIGKSPFKFRLGIGSVIKGWDVGVNGMRVGDKRKLTIPPSMGYGVKGAGGQIPPNSWLTFDVELINVQ
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Histone chaperone possibly involved in H3/H4 deposition to the nucleosome.  Associates with 18S rDNA chromatin and negatively regulates the level of its expression.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP53, PPIase FKBP53, FK506-binding protein 53, AtFKBP53, Immunophilin FKBP53, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LV1C_MOUSE
Sequence: QAVVTQESALTTSPGETVTLTCRSNTGAVTTSNYANWVQQKPDHLFTGLIGNTNNRAPGVPARFSGSLIGNKAALTITGAQTEDEAIYFCALWYSNRWVFGGGTKLTVLG
What are the official names of this protein?
Ig lambda-1 chain V region S178.
Protein: THIG_PARMW
Sequence: MVPNPPISLAQGDDLIIGGRRFHSRLFTGTGKYPSMEVMQQSIKRSACEMVTVAVRRVQAVAAGHAGLMEAIDWTRIWMLPNTAGCTNAEEAVRVARLGRELAKLAGQEDNTFVKLEVIPDGRHLLPDPIGTLQAAEQLVNEGFTVLPYINADPLLAKHLEDAGCATVMPLGSPIGSGQGLNNAANIALIIENASVPVVVDAGIGVPSEAAQALEMGADAVLVNSAIALARNPAAMAEAMGQAVIAGRTAFCAGRLPRREEASASSPTTGLVSS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTMS_BOVIN
Sequence: MSEKSVEAAAELSAKDLKEKKEKVEEKAGRKERKKEVVEEEENGAEEEEEETAEDGEEEDDGDEEDEEEEEEEDEGPALVRAAEEEDEADPKRQKTENGASA
What is the function of this protein?
Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.
What are the official names of this protein?
Parathymosin.
What is the protein family that this protein belongs to?
Belongs to the pro/parathymosin family.
Protein: RBSU_STAAC
Sequence: MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
What is the function of this protein?
Could be involved in the uptake of ribose.
What are the official names of this protein?
Putative ribose uptake protein RbsU.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SRP19_PYRCJ
Sequence: MKKRGGRILWLVYLDSTIPKSRGRIIAKGVAVPKPTIQEVEEALRRLGYSYESYPEKKYPPLWFEERARGYFLVKSDEKPASIAAKVAEEIRRIRGQ
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y731_HAEIN
Sequence: MHQQYYNKPLHKLENNIDVTNGLINQRRFDPRKVDVMARKGTIERWILNASLPVGFTIQGAKFVVESQGEHQLQAEELAWKDTVWVKNKTQILVKFDQASSGNYPFLFGVSNLMLEDMGCLGVLMVQ
What are the official names of this protein?
Uncharacterized protein HI_0731.
Protein: PGP2L_DROME
Sequence: MQQSTGAATSSAADSGMGATDLVSRCVGDGGGGGGNSCSGGSSDPAAINTTISSKQADAREPQEQQVAIHYLASFHELCVVTALLPLVTLFTCFVTAYVFQYDDVHETHCRVYNIIPSISAITGVSPQRYFWRFSIALHIGPRIPIAFVYKNYYRSQLRRISPAQVPQTSLLITLILVLNCIEIASLGGVTYISNRENYPVHERIFITFMVCSLCYMLATIKLNGILNAGQALSEKQLLSIKWKKILFAVSILSTVGLLVFFAKHRFYCHDLAFSWFAFFEYLIAIANMLFHFTIIWDFPSQFMMIVQGPRENLAQYLSNRPKLD
What are the official names of this protein?
Post-GPI attachment to proteins factor 2-like.
What is the protein family that this protein belongs to?
Belongs to the PGAP2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MEND_BACAN
Sequence: MNNHIEALSYYLGAFVDELTLLNVCDVVISPGSRSTPIALLMEQHEGMNTYLHVDERSAGFFALGIAKAKKRPVALLCTSGTAAANYYPAVCEAFHSRVPLIVLTADRPHELRDVGAPQAMNQINLYGTFVKQFTEMALPEASEAMYHYARLTTQRMIASACLAPQGPVHLNFPVREPLIPDFSLESLWDKGRGEYTGVVQQGNAVMPSEYVDSLVGRLSHMEKGLIICGDDSHSEIAAFATQLAEKTGYPILADPLSNIRSGHHDKTMVIDCYDTFLRNELLKETWKPDVLIRFGGMPVSKALTQFIKKQTKAVHIVVDESGQWRDPALVATEVVQASDIAFCSALIEKMPVMKKNDWFRMWQHINEKTKETLREMETYDTAFEGRVITDIVRVLPEGATLFASNSMPIRDTDSFFFTSDKNIQVMANRGVNGIDGIISTALGASMICDPLVLVIGDLSFYHDLNGLLAAKLHELNITIVVVNNDGGGIFSFLPQYEKKEHFESLFGTPIGLDYEHVVTMYGGSFSRVNGWEQFREEVQKGVTTEGLHVVEICTNRDENLTLHRTLWAKTQDVITTSLQGESK
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: TXS2B_HORWA
Sequence: MNFATKVSLLLLAIAVIVIVEGGEGDSWFEEHEESDTERDFPLSKEYESCVRPRKCKPPLKCNKAQICVDPNKGW
What is the function of this protein?
Affects the activity of both ryanodine-sensitive calcium-release channels RyR1 and RyR2 with high potency.  At lower concentrations the toxin increases full openings of the RyRs, and at higher concentrations it inhibits full openings and induce openings to subconductance levels and reduces the number of full conductance openings.  The different actions may be attributed to the toxins binding at different sites on the RyRs, with binding at a high-affinity site mediating the increase in full openings and the induction of subconductance states evoked upon binding to a lower-affinity site.  Insect-selective toxin that provokes a dose-dependent contractile paralysis in crickets and blowfly larvae, followed by death.
What are the official names of this protein?
Phi-liotoxin-Lw1a, Phi-LITX-Lw1a, U1-liotoxin-Lw1a, U1-LITX-Lw1a.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRH_HAES1
Sequence: MSQPIYKRILLKLSGEALQGDEGFGIDPSILDRMALEIKGLLGLGVEVGVVLGGGNLFRGAKLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRANVNAKLMSAFQLNGICDTYNWSEAIKMLCEKRVVIFSAGTGSPFFTTDSAACLRGIEIEADVVLKATKVDGVYDCDPVKNPNAVLYHKLSYAEVIEKELQVMDLAAFTLARDHNMPIRVFNMSKTGALRNVILGKTEGTLICD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCE1_FELCA
Sequence: MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDGRFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKFFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILEAKQKGYVPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGIPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
What is the function of this protein?
Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor.
What are the official names of this protein?
Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: NIKR_RHOPS
Sequence: MHRVTITLDDDLMERLDAIIAVRGYQNRSEAIRDLARIGIQQTSAHDSGERCVGAMVYTYDHSKRDLPRKLTQSFHNHHDLSRATMHVHLDHDQCLEVTILDGKASELQHFADHIFSERGVRYGRLVTIPTMDDEQHTHD
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: DAPD_MYCTU
Sequence: MSTVTGAAGIGLATLAADGSVLDTWFPAPELTESGTSATSRLAVSDVPVELAALIGRDDDRRTETIAVRTVIGSLDDVAADPYDAYLRLHLLSHRLVAPHGLNAGGLFGVLTNVVWTNHGPCAIDGFEAVRARLRRRGPVTVYGVDKFPRMVDYVVPTGVRIADADRVRLGAHLAPGTTVMHEGFVNYNAGTLGASMVEGRISAGVVVGDGSDVGGGASIMGTLSGGGTHVISIGKRCLLGANSGLGISLGDDCVVEAGLYVTAGTRVTMPDSNSVKARELSGSSNLLFRRNSVSGAVEVLARDGQGIALNEDLHAN
What is the function of this protein?
Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_AZOVD
Sequence: MQLGLDFGRVEALVAGVDEVGRGPLCGAVVTAAVILDPERPILGLNDSKKLSEARREALSEEIREKALAWCIARAEVEEIDRLNILHATMLAMRRAVEGLAVTPRLALIDGNRCPKLAVPCAPVIKGDAQVPAIAAASILAKVARDREMLVLDALYPGYGLARHKGYPTAVHLEALARLGPTPIHRRSFAPVRELLDVVSIPCAPTS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD89_HUMAN
Sequence: MRAPMLQKQQAPRMDTPPPEERLEKQNEKLNNQEEETEFKELDGLREALANLRGLSEEERSEKAMLRSRIEEQSQLICILKRRSDEALERCQILELLNAELEEKMMQEAEKLKAQGEYSRKLEERFMTLAANHELMLRFKDEYKSENIKLREENEKLRLENSSLFSQALKDEEAKVLQLTVRCEALTGELETLKERCAQDACQAQAREKELLELQSQQACTHTKETEQLRSQLQTLKQQHQQAVEQIAKAEETHSSLSQELQARLQTVTREKEELLQLSIERGKVLQNKQAEICQLEEKLEIANEDRKHALERFEQEAVAVDSNLRVRELQRKVDGIQKAYDELRLQSEAFKKHSLDLLSKERELNGKLRHLSP
What are the official names of this protein?
Coiled-coil domain-containing protein 89, Bc8 orange-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CCDC89 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Uniformly distributed within the cell, but becomes recruited to the nucleus upon binding to HEY1.
Protein: LFTR_LEPBJ
Sequence: MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRGIFDLNKLHISKRLKRKINQKRYTITFNRAFEQVMRCCAYRPGEETWITDLFIKSYTEFHKLGYAHSIEVWDENGNLGGGVYGVAIGNFFAGESMFSFISDFGKIGLFHLFEALKKDQFTLFDTQQLNIVTLCLGAYQIPKKEYLRRLESAVASGKKWNPLRTVF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13A_MACFA
Sequence: MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTTTLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTQVLKTHGLLV
What is the function of this protein?
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions.  Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.  Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.  In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex.  Involved in methylation of rRNA.
What are the official names of this protein?
60S ribosomal protein L13a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_RHIME
Sequence: MLNEFKEFIARGNVMDLAVGVIIGAAFSKIVDSVVNDLVMPVVGAITGGGFDFSNYFLPLSASVTAPTLSAAREQGAVFAYGNFITVLINFLILAWIIFLLIKLVNRARASVERDKAPDPAAPPPQDILLLSEIRDLLRQRA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALLR_ECOUT
Sequence: MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHL
What is the function of this protein?
Negative regulator of allantoin and glyoxylate utilization operons.  Binds to the gcl promoter and to the allS-allA intergenic region (By similarity).
What are the official names of this protein?
HTH-type transcriptional repressor AllR, Negative regulator of allantoin and glyoxylate utilization operons.
Protein: RL1_CHLAD
Sequence: MPKHGKKYLAALAKVDRSRFYTPAEAIALVKETSYTKFDATVEAHLRLGIDPRHADQNIRTTVALPHGTGKTVRVLVFAQGEALQTALDAGADYAGSDDLIARIDRENFFDFDVAIATPDMMGKVGRIGRKLGPRGLMPNPKSGTVVQPADLARTIREVKGGRVEIRNDKTGILHVAIGKVSFTSQQLSENLAALMEAVKAAKPSGAKGTYIRSVTLTSTMGPGVPVDLVAVQNLKL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: H4_STYLE
Sequence: MAGRGKVGKGYGKVGAKRHTKKSLKETIMGITKPAIRRLARRGGVKRISSLIYEETRNVLRSFLENVIRDSVTYTEHAKRKTVTALDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TSNR_STRAJ
Sequence: MTELDTIANPSDPAVQRIIDVTKPSRSNIKTTLIEDVEPLMHSIAAGVEFIEVYGSDSSPFPSELLDLCGRQNIPVRLIDSSIVNQLFKGERKAKTFGIARVPRPARFGDIASRRGDVVVLDGVKIVGNIGAIVRTSLALGASGIILVDSDITSIADRRLQRASRGYVFSLPVVLSGREEAIAFIRDSGMQLMTLKADGDISVKELGDNPDRLALLFGSEKGGPSDLFEEASSASVSIPMMSQTESLNVSVSLGIALHERIDRNLAANR
What is the function of this protein?
Specifically methylates the adenosine-1067 in 23S ribosomal RNA.  Confers resistance to antibiotic thiostrepton.
What are the official names of this protein?
23S rRNA (adenosine(1067)-2'-O)-methyltransferase, 23S rRNA [AM1067] 2'-O-methyltransferase, 23S rRNA methylase, Thiostrepton-resistance methylase, rRNA (adenosine-2'-O)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TsnR/AvirB family.
Protein: RL24_LIGS1
Sequence: MFIKKNDKVKVIAGKDKGKEGTVEKVFPAQDRVIVKGINIVKKHQKPTNANPNGGIVEVEAPIHVSNVMLIDPSNNEATRVGFKVVDGKKVRVSKKSGEIL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL23_TOLAT
Sequence: MIREERLLKVLKAPHISEKSTMVAEKLNTIVFKVATDATKAEIKAAVEKLFEVKVEAVRTLNVVGKTKRTGSRMGRRSDWKKAYVTLVEGQDIDFVGGAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.