PharMolix/UniProtQA huggingface dataset:
Protein: PDC6I_RAT
Sequence: MASFIWVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRSALGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKTAAKQYQFASGAFLHIKDTVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDALPKYFYFQEVFPTLAAKQCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKNVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKPTPVNVPISQKFTDLFEKMVPVSVQQSLAVFSQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTKSTAVVEQGGIQTVDQLIKELPELLQRNREILEESLRLLDEEEATDNDLRAKFKDRWQRTPSNDLYKPLRAEGAKFRAVLDKAVQADGQVKERYQSHRDTIALLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEIKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRIYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNSEASLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPAYQSSPAGGHATAPTPAPRTMPPAKPQPPARPPPPVLPANRVPPAAAATAPAGVGTASAAPPQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYTYGQYNMPYPPVYHQSPGQAPYPGPQQPTYPFPQPPQQSYYPQQ
What is the function of this protein?
Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity.  Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome.  Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes.  The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complexes.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.  Adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes.  Required for completion of cytokinesis.  May play a role in the regulation of both apoptosis and cell proliferation.  Regulates exosome biogenesis in concert with SDC1/4 and SDCBP (By similarity).  By interacting with F-actin, PARD3 and TJP1 secures the proper assembly and positioning of actomyosin-tight junction complex at the apical sides of adjacent epithelial cells that defines a spatial membrane domain essential for the maintenance of epithelial cell polarity and barrier (By similarity).
What are the official names of this protein?
Programmed cell death 6-interacting protein, ALG-2-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Secreted, extracellular exosome. Cell junction, tight junction. Midbody, Midbody ring. Note=Colocalized with CEP55 in the midbody during cytokinesis and at centrosomes in non-dividing cells (By similarity). Component of the actomyosin-tight junction complex (By similarity).
Protein: COBQ_TRIEI
Sequence: MKAIMVVGTTSHAGKSLITTAICRILSRRGWKVTPFKGQNMALNSYVTSTGGEMGHAQAVQAWAAGVTPAIEMNPILLKPQGDMTSQVIIKGKASGTVGAVDYYQQYFDIGWNAIQESLETLSQEFNMIVCEGAGSPAEINLKHRDLTNMRVAKHLNASTILVVDIDRGGAFAHIIGTLELLEPEERNLIKGIVINKFRGQRSLLDSGIHWLEKKTNIPVIGVIPWINEAFPAEDSLSILEQRYNKHTTDITIAIIRLPRISNFTDFEPLEAESSVKIKYIHPNDSLGDPDAIIIPGTKTTINDLLVLQKSGMAEAIKSYQSSGGIVMGICGGFQMLGEVLIDSQGLEGKQGEYKGLELLPLITTITPKKIASQRQVIANYPLGNLPVIGYEIHQGRTIVTKPDIVKPLFNDYDLGFVDSYDSIWGNYLHGIFDNGSWRRSWLNILRHKRGLNSLPTSISNYREQREIILDSIADKVNEHLDLKPVLT
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: HSLO_PSEPF
Sequence: MTDFLDTDYTQRFIFDDSDTRGELVSLERSYAEVLAKHPYPEPVAQLLGELMAAASLLVGTLKFDGLLILQARSEGPIPLLMIECSSEREIRGLARYHAEQIPADATLGDLMPNGVLALTVDPIAGQRYQGIVDLDGETLSDCFTNYFVMSQQVGTRFKLCADGRRARGLLLQQLPADRLKDEEERAASWQHITALGNTLTADELLSLDNETVLHRLYHEEQVRLFDVQKLRFHCSCSRERSGNALVSLGLEDAQALVAEQGGQVEIDCQFCNQRYLFDAADIAQLFAGAGVETPSDTRH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK1_RHOBA
Sequence: MATGVSSRDGSRERIRRRAVARDHPGCGPHRLDRPIGHIRYPHRHSISFSPFASLTLSHDPAPSQSVGKRPQKSTKTASRRKVETAAADAPRFINRELAWLEFNARVLDQADDPSVRLLERAKFLAITSSNLDEFMMVRVGSLKLQAVSGGGRRDPSGRTATEQLQAISKRCQGHVDRQYELLRNELLPLLGEHKINQVDPAECSDRLLAAAERHFRGDVLAVLSPQALHDRRFPMLPGLGIHLCVQLRPGDEIGPQRTPPPSDSLDNRVPSNLKRNSDTANQQPTPAENISAPEDGAEQTEPETQFAVIPLGRTLGRVIPLPIEKPPIEKGVAPKESDDTSPIESGYSYALLEDLVSHFVDEFFPGREVIQCKPFRITRNADIELREDGAGDLLGGMEEVLESRRLSDVVRLEIDANANSEIRDYLIKSFNVDPQFVFDIDGPLDLTYLFALHGLKGMNTLRDDEWPPQRSPRIDPAESMFTSISDGDIMLMHPYESFDPVVRLLEEASVDPDVLAVKQILYRTSRNSPIVAALMRAAERGKYVTAIVELKARFDEARNIEWAREMEQAGVQVIYGIRGLKTHAKVCIIVRREPQGLVRYVHFGTGNYNEVTANLYGDISVLTCDEILGTDATMFFNAVTGASQPQPLQQLGMAPLTLRRQILDLIQGETERSRQGQKGEIIAKMNALVDTEVIDSLYMASQAGVKIRLNVRGVCCLRPGVPGMSETIEVVSIVDRFLEHARTFYFRHGGDHEMFISSADWMPRNLDRRVELLVPVIDPAARKRLRETLQLYFRDNQNAWRMQPDGSYQRLKPRKNEAPMRVQETLYHQVVENRKAGKHAPQSTFETHRPD
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: GLUC2_ORENI
Sequence: HAGTYTSDVSSYLQDQAAKEFVSWLKTGRGRRD
What is the function of this protein?
Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level.
What are the official names of this protein?
Glucagon-2, Glucagon II.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSB9_BOVIN
Sequence: MLRTGAPNGDLPRAGEVHTGTTIMAVEFDGGVVVGSDSRVSAGEAVVNRVFDKLSPLHQHIYCALSGSAADAQAIADMAAYQLELHGMELEEPPLVLAAANVVRNITYKYREDLSAHLMVAGWDQREGGQVYGTMSGMLIRQPFAIGGSGSTYIYGYVDAAYKPGMSPEECRRFTTNAIALAMKRDGSSGGVIYLATITGAGVDHRVILGDELPRFYDE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  This subunit is involved in antigen processing to generate class I binding peptides (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-9, Proteasome subunit beta-1i.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VKT2_PSEPO
Sequence: MSSGGLLLLLGLLTLWEGLTPVSSKDRPDFCELPDDRGPCRGIFHAFYYNPDQRQCLEFIYGGCYGNANNFKTIDECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor blackelin-2.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: PIMT_BURPS
Sequence: MSGERAKRFPLALEDLKREPRKPEGRVAERQAAGDAARQRLTAAAAVPAAASPIVPERRAPHGGVFAAKPARAKQHAPAAPGAAKRAPQGGAKQGDRSAAPNVALSGALALTSERVRERMVERLRANGVADPRVLAAMSAVPRHMFVDPGLAAQAYEDAALPIGHQQTISKPSVVARMIELAAAGRALERVLEIGTGCGYQAAVLSRVARDVYSIERVKPLYERAKLNLRPLRVPNIRLHYGDGRVGLPAAAPFDAIVIAAAGLDVPRALLEQLAIGGRLVAPVGEQAGEQVLTLVERVAPAQWRESRLDRVFFVPLKSGVI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALT_STRMU
Sequence: MTALLDTFVSKIIENSDYAELDATYLSNRILALVGEDNAQQDTNQSNLIALKDELVDLAVVNGKVGDLAEEKDCLGAELMNFITPIPSQVNKAFWDTNAKSPQKAIKDFYELSKRNNYIKVTAIAKNIAFTTSSVYGDIDITINLSKPEKDPKAIAAAKLAKTSNYPKCQLCMENEGYQGRINYPARANHRIIRMNLGDEKWGFQYSPYAYFNEHCIFLNTEHVPMVISQNTFRQLLDIVDIFPGYFAGSNSDLPIVGGSILSHNHYQGGRHIFPMEIAELDSVFRFKDFPDVTAGIVKWPMSVIRLRGANKYSLVELAEIIRLAWRNYSDDTMNILAFTGDTPHHTVTPIARKRDGQFELDIVLRDNHTTAEYPDGVYHPHIDVQHIKKENIGLIEVMGLAILPPRLKKELAEVEKYVLNQYNEMADYHKDWADAIKASHPETSSETVSEIVKQAVGRTFVRVLEDAGVYKRNRQGQAAFMRFVESIGVK
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_HALSA
Sequence: MPWAALLAGMHATVSPSRVRGRARAPPSKSYTHRALLAAGYADGETVVRDPLVSADTRATARAVELLGGAAARENGDWVVTGFGSRPAIPDAVIDCANSGTTMRLVTAAAALADGTTVLTGDESLRARPHGPLLDALSGLGGTARSTRGNGQAPLVVDGPVSGGSVALPGDVSSQFVTALLMAGAVTETGIETDLTTELKSAPYVDITLDVLDAFGVGASETAAGYRVRGGQAYAPSGAEYAVPGDFSSASYLLAAGALAAADGAAVVVEGMHPSAQGDAAIVDVLERMGADIDWDTESGVITVQRSELSGVEVGVADTPDLLPTIAVLGAAADGTTRITDAEHVRYKETDRVAAMAESLSKLGASVEERPDELVVRGGDTELSGASVDGRGDHRLVMALAVAGLVADGETTIAGSEHVDVSFPDFFEVLAGLGADTDG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAC2_DICDI
Sequence: MSTPTLPNLSQLHGIQNQSLQQQQQQQPQQQQQPQQQQQQQQPQQTMQQPIQNLHQQAPQMQQPQYNLHTTLPPPLMNPNGLGLMGHNMMGGGNNGNNSGNNNGQPQMHGTNLNGLSLAIQNQSSLPQPINNNNNNNNNNSNINNNNNNSNNNNNNNNSNLGINSSPTQSSANSADKRSRGRPRKNPPSEPKDTSGPKRKRGRPPKMDEEGNPQPKPVPQPGSNKKRGRPKKPKDENESDYNNTSFSDSNTDGTPKKRGRPPKAKGDSPSASPTHNTLGNGILNSNNNNNNNNNNSNINNINNNNNNNSNNNNNSSNNNNNNNNSTNNNTNNNNNNTNNNTNNNNNNINNNNNNTNNNNNNANNQNTNNNNMGNNSNNNNNPNNNNHQNNNNNNTSNNSNTTTATTTAPGGNNLTNSLNNAGNLGNLGRVSGLHSSDPNNPNAQKSFPDSTNTMDFQPNFSFFH
What are the official names of this protein?
AAC-rich mRNA clone AAC11 protein.
Protein: FUCI_HAEIN
Sequence: MALATQSNRIKIGIRPTIDGRRMGVRESLETQTIRMAQSVAQLLQTHIRHTDGTFVECVVADSTIGGVAEAAACADKFKRENVGLTITVTPCWCYGSETIDMDPHMPKAIWGFNGTERPGAVYLAAALAGHSQLGLPAFSIYGTEVQEADDTNIPEDVKEKLLRFARAGLAVASIRGKSYLSIGSVSMGIAGSIVNQAFFQEYLGMRNEYVDMMEIKRRLDRKIYDQEEVDLALSWVKQYCKEGVDVNSLENQRNAEERAELWENVVKMTIITRDLMVGNPKLATLNYAEEALGHNAIAAGFQGQRHWTDHLPNGDFMEAMLNSTYDWNGVRPPYILATENDSLNAIGMLFGHQLTGKAQIFADVRTYWSQDSVERVTGWRPESGFIHLINSGSAALDGTGEHQDAQGNPTLKPAWDVTEEEAKRCLENTRWCPAVHEYFRGGGLSSQFLTKGGIPFTIHRINLIKGLGPVLQIAEGWSIDLPQDVHNKLNQRTNETWPTTWFVPRLTGKGAFTDVYSVMANWGANHCVATHGHVGADLITLASMLRIPVCMHNVSEKNIFRPSAWNGFGQDKEGQDYRACQNFGPLYK
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP49_CHATD
Sequence: MSLFGTNTTSQTPAGGGLFGTTTSQSAQTGSLFGTATSQPQQTGGLFGSTATQTPSSQLQSTGLFGSTTATSQPQQTGGLFGSTTTTTSQPQQTGGLFGATATSQPQSTGGLFGNTTTTSQPAQTVGLFGTTTQPQPAQSGGLFGSATQQKPATGGLFGSTTTNTGAGLFGNTSNTIGGGGLFGQTAKPATGGLFGQSTTQPQQQQNATPGLTMGQSTNTQQQVVPGVRIDLSNIKSTTRFNDLTEALQQEIAKIDEEIQKCIRDKEAVDAFLPAHGEQLAAIPTDVNFVTRKSEGAHNALSSDILAIDQLRELVKQDADNARLSFKAIDNLKLPMQYHQAGLWSKQMGGAGTAGASGASADADGQSNADLISYFSKTADEMEEMMKKFEKTITEIEAHLTGVEAHAMAMQNVAAQSRNAAQGGVDERVYELAAVLREFEESILKVAGVVGGVKEGVTELQLRDFMGHGS
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm).  NUP49 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, and pre-ribosome transport.
What are the official names of this protein?
Nucleoporin NUP49, Nuclear pore protein NUP49.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin GLFG family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: RS9_ALIFM
Sequence: MAENQYYGTGRRKSSAARVFIKPGTGNIVINKRSLEVYFGRPTARMVVNQPLELVEMTDKLDLYITVSGGGISGQAGAIRHGITRALMQYDESLRPALRAAGYVTRDARCVERKKVGLRKARRKPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: DNLJ_NEIMB
Sequence: MNPNSKHNTNFTNLLKPSDSDIKQFAAQHICRLTDLLNRYAYEYYTLDAPSVPDAEYDKLFRELEALELNHPELKLPDSPTQRVGGEPLAGFAEVRHEVPMLSLTNAFSPQDENGVFDHAEMYAFDQRVRDGLDGGNPEYVIEPKFDGLAISLLYRDGVLVQAATRGDGTTGEDVTQNIKTVSNIPLRLHGENTPELIEVRGEVLMLKADFVALNKRQAENGQKPFANPRNAAAGSLRQLDSRITAQRKLHFFPYSVARQQDGFVAEEHIQELAYFQALGFSLPNGNFGCFKNIDEVLAFYEHMQQKRPELPYEIDGMVVKVNSLAQQHELGFISRAPRWAVAHKFPAEEALTIVEAIDVQIGRTGAVTPVARLQPVFVGGVTVTNATLHNQDEVSRKDVRVGDTVVVRRAGDVIPEVVRVIFERRPMRETAVAVSDGIGHRQDDLFAETPSANQTQSVPLHKPYRLPTHCPICRSEIEREEGEAVARCSGGMLCQAQRAQGLIHFASRKAMDIDGLGEKQIEQLVAQDLVRHFADLYRLDIPTLQKMKETADKTVAESDQMPSEGSSVGASGKHKKQPVKWAENILAGIEASKTPELARFLFALGIRHVGERTAKTLAQAFGTLERVRRAPEPVLACLPDIGTVVARSIAHFFAQAEQQAMIDELLAAGVAPQTQAVTIPPARHAEPQRWIARLPGFKISENKAQALWELAGKNIEGLQTDKALPTDWQAWRSEPQNAALLENLKTFFAQMPSEDEAAQGSDGINKAVAGKTFVLTGTLPTLKRDQAQSLIEAAGGKVSGSVSKKTDYVVAGEAAGSKLEKANALGVSVLSEAELLTLLG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SYD_STAAT
Sequence: MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP6B_SACSH
Sequence: MSAKEKFTSLSPAEFFKRNPELAGFPNPARALYQTVRELIENSLDATDVHGILPNIKITIDLIDDARQIYKVNVVDNGIGIPPQEVPNAFGRVLYSSKYVNRQTRGMYGLGVKAAVLYSQMHQDKPIEIETSPVNSKRIYTFKLKIDINKNEPIIVERGSVENTRGFHGTSVAISIPGDWPKAKSRIYEYIKRTYIITPYAEFIFKDPEGNVTYYPRLTNKIPKPPQEVKPHPYGVDREEIKILINNLKRDYTIKEFLVNEFQSIGDTTADKILELAGLKPNKKVKNLTEEEITRLVETFKKDEDFRSPSADSLSVIGEDLIELGLKKIFNPDFAASITRKPKAYQGHPFIVEAGVAFGGSIPVGEEPIVLRYANKIPLIYDEKSDVIWKVVEELDWKRYGIESDQYQMVVMVHLCSTKIPYKSAGKESIAEVENIEKEIKNALMEVARKLKQYLSEKRKEQEAKKKLLAYLKYIPEVSRSLATFLASGNKELVSKYQNEISEGLFKLISKKLDLINIEEYRKVYRVDSE
What is the function of this protein?
Relaxes both positive and negative supercoils and exhibits a strong decatenase and unknotting activity; it cannot introduce DNA supercoils (PubMed:7961685).  ATP is absolutely required for DNA cleavage; the nonhydrolyzable analog AMP-PNP generates nicked or linear products from a supercoiled dsDNA substrate.  Generates staggered two-nucleotide long 5' overhangs.  The enzyme is covalently attached transiently to the 5'-ends of the cleaved strands (PubMed:11485995).
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: OBLD_ASPCL
Sequence: MNEDHEAGNSSREAEVHQLARQFTDQSNYSAAGQNPFAVEAGSALDPNGEHFNARAWCKAMLQMHTGDKQAHPLRTLGVAFSNLNVHGFGSDTDYQKSVGNVWLEVLSLVSKAFGQKQRKIEILQNMEGLVEAGEMLVVLGPPGSGCSTFLKTIAGETYGFHVDKNSNINFQGIAKQMAHEFRGEAIYTAEVDVHFPKLTVGDTLYFAARARAPRHIPGGVNATQYASHMRDVIMAMFGISHTKNTIVGNDFIRGVSGGERKRVSIAEACLSNAPLQCWDNSTRGLDSANAIEFCKTLRMQADINGTTACVSLYQAPQAAYDYFDKALVLYEGREIYFGRTSMAKQYFLDMGFVCPDRQTDADFLTSMTSHLERVVQPGYEGRVPRTPDEFAARWRASPQRAQLLQDIKCYNAKFALDGEYLDKLKQSRRAQQAKAQRVSSPYTLSYVQQVELCLWRGYQRLKADPSVTISSVFGNTIISLVIASIFYNLKADTSTFFQRGALLFFAVLMNALGCGLEMLTLYAQRGIIEKHSRYALYHPSAEAFSSMIMDLPYKIINAITSNIVLYFMTNLRREPGAFFFFVFTSFVLTLTMSMFFRSMASLSRSLVQALPFSAVLLLGLSMYTGFTIPTGYMLGWARWIAYINPISYGFESLLINEFHNRDFPCMNYVPSGPGYTDLGLNNRVCSTVGSVPGQAFVNGDAYIESAYIYTASHKWRNIGVIFAYMFLLAAVYLVATDFITEKKSKGEILVFPRGHEALKKGKSDEDLEEGSGRSVTVEKTGSDGLTMIERQTAIFQWKDVCFDIKIGKENRRILDHVDGWVKPGTLTALMGVSGAGKTTLLDVLATRTSVGIISGEILVDGQPRDDSFQRKTGYAQQQDLHLSTATVREALEFSALLRQSAHVPRQEKIDYVTEVIKLLDMTEYADAVIGVPGEGLNVEQRKRLTIGVELAARPQLLLFLDEPTSGLDSQTSWAILDLLDKLKKNGQAILCTIHQPSAMLFQRFDRLLFLQAGGRTVYFGEVGENSQILIDYFVRNGGPPCPPAANPAEWMLDVIGAAPGSHTNINWFETWRKSPEYARVQEHLAELKRERPEQTNLFRTTSSQKREDKASYREFAAPFCAQLCEVQVRVFQQIWRSPTYIYSKTALCVLSALFVGFSLFHTPNTIQGLQNQMFGIFMLLTVFGQLIQQIMPHFVAQRALYEVRERPAKTYSWKAFIISNIVVELPWNSLMSVLMFLCWYYPIGLYRNAEPTDAVSLRGTQMWLMVWTFLLFSSTFAHFMIAAFDAAENAGNLGNLLFLLCLIFCGVLATPGQLPGFWIFMYRVSPFTYLVSGMLSVGISNTNATCADNEYLRFDPVNGTCGKYMDSYISNMGGYLEDEMATSDCSFCPIKETNVFLSSVSSSYSEIWRNFGLMWVFIVFNIFAACLLYWWVRVPRVKKPVAKTE
What is the function of this protein?
ABC-type transporter; part of the gene cluster that mediates the biosynthesis of the sesterterpenes ophiobolins, fungal phytotoxins with potential anti-cancer activities (PubMed:27116000).  Acts as a specific transporter involved in ophiobolins secretion (By similarity).
What are the official names of this protein?
ABC-type transporter oblD, Ophiobolin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSUD_ERWP6
Sequence: MRLSVFWFLPTHGDGKYLGTNEGARPVDHAYLQQIAQAADRLGFGGVLIPTGRSCEDAWLVAASLIPVTQRLRFLVALRPGVISPTQAARQAATLDRLSNGRALFNLVTGGDAEELAGDGVFLDHGERYAESAEFTRVWRRVLEGETVDYKGKHVHVRGARLMFKPVQQPRPPLWFGGSSEVAQDLAAEQVDVYLTWGEPPAQVKEKIARVQAKAAARGRKVRFGIRLHVIVRETNDEAWQAADRLISHLDDQTIAKAQAALARTDSVGQQRMAALHGGKRDRLEISPNLWAGVGLVRGGAGTALVGDGPTVAARMQEYADLGIETFILSGYPHLEEAYRVGELLFPHLELNIPEVPKPAAVQAHGEHVAHDFAPQKVPQGER
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: PUR5_NEIG1
Sequence: MSTSLSYRDAGVGIDAGDQLVEKIKPFAKRTMRPEVLGDLGGFGALVEIGKKYQNPVLVSGTDGVGTKLKLAFDWDKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVPRATDVIKGIAQGCEESGCALIGGETAEMPGMYPVGEYDLAGFAVGVVEKENVITGLSIGAGDVVLGLASNGAHSNGYSLIRKIIERDNPDLDAEFDNGKTLREAVIAPTRLYVKPILAALEKFTIKGMAHITGGGITENVPRVLPKNTVAQIDAESWELPKLFQWLQKAGNVETQEMYRTFNCGIGMVVIVAAEDADAVRSFLSGQGETVYRLGCIRERQGNEHQTQVA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFL_BRUSU
Sequence: MTVRLIVKYPDPRLRAAAEPVTTFDEGLRKLADDLLDTMRAAPGIGITAPHIGISKRVVVLELDRAAGPKIYINPEIVWACEEKIRHQEGSVSMPGVVDEVERHARIRLRYQDLDGNEQTEESDGLLAVCHQHEIDQLDGIFWVQRLSRLRRERLIKRYEKLQR
What are the official names of this protein?
Peptide deformylase-like, Polypeptide deformylase-like.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: NMD3_YEAST
Sequence: MEFTPIDPHQHQNAATLLCCNCGTPIDGSTGLVMCYDCIKLTVDITQGIPREANISFCRNCERFLQPPGQWIRAELESRELLAICLRRLKGLTKVRLVDASFIWTEPHSRRIRIKLTVQGEAMTNTIIQQTFEVEYIVIAMQCPDCARSYTTNTWRATVQIRQKVPHKRTFLFLEQLILKHNAHVDTISISEAKDGLDFFYAQKNHAVKMIDFLNAVVPIKHKKSEELISQDTHTGASTYKFSYSVEIVPICKDDLVVLPKKLAKSMGNISQFVLCSKISNTVQFMDPTTLQTADLSPSVYWRAPFNALADVTQLVEFIVLDVDSTGISRGNRVLADITVARTSDLGVNDQVYYVRSHLGGICHAGDSVMGYFIANSNYNSDLFDGLNIDYVPDVVLVKKLYQRKSKKSRHWKLKRMAKEHKDIDASLDYNSRAQKQEMERAEKDYELFLQELEEDAELRQSVNLYKNREANVPPEEHEMDEDEDEDAPQINIDELLDELDEMTLEDGVENTPVESQQ
What is the function of this protein?
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.  Unlikely to play a significant role in nonsense-mediated mRNA decay (NMD).
What are the official names of this protein?
60S ribosomal export protein NMD3, Nonsense-mediated mRNA decay protein 3.
What is the protein family that this protein belongs to?
Belongs to the NMD3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Note=Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner.
Protein: RBSD2_STRGG
Sequence: MKKSGILNRHLAGAIAELGHGDTVLVCDAGMPIPPGPRVIDLAFRAGTPSFAEVLDGLLDELVVEGATAAEEIRDANPDAAALLDVHFPWLEAVPHDELKARTAAARLVVRTGEARPYANVLLRCGVFF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase 2.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_CARHZ
Sequence: MPRAKSSVVSRKRHKKILKLAKGYFGAKSKLFRVAKQQVMKSLMYAYRDRRARKREFRKLWITRINAAARMHGLTYSRMMNGLKKAGVEINRKMLADLAVNDKNAFAELVEIAKKNL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: Y079_OSHVF
Sequence: MNFEAISLEMSLMWLHKNNKLMGFLNQEAPEVNIFDQFLFEDRDKKMLKEDDEFCDPPAQTFNEPAPSTSKITDVDIEFYNSMAEEFDSPMDEEEETKPREASLDQTAPKKSKKEELLVKNNNFSTNNVKKLQFKKSVRLRSKRRS
What are the official names of this protein?
Uncharacterized protein ORF79.