PharMolix/UniProtQA huggingface dataset:
Protein: RCI2_ECOLX
Sequence: MPSPRIRKMSLSRALDKYLKTVSVHKKGHQQEFYRSNVIKRYPIALRNMDEITTVDIATYRDVRLAEINPRTGKPITGNTVRLELALLSSLFNIARVEWGTCRTNPVELVRKPKVSSGRDRRLTSSEERRLSRYFREKNLMLYVIFHLALETAMRQGEILALRWEHIDLRHGVAHLPETKNGHSRDVPLSRRARNFLQMMPVNLHGNVFDYTASGFKNAWRIATQRLRIEDLHFHDLRHEAISRFFELGSLNVMEIAAISGHRSMNMLKRYTHLRAWQLVSKLDARRRQTQKVAAWFVPYPAHITTINEENGQKAHRIEIGDFDNLHVTATTKEEAVHRASEVLLRTLAIAAQKGERVPSPGALPVNDPDYIMICPLNPGSTPL
What is the function of this protein?
Shufflon-specific DNA recombinase.
What are the official names of this protein?
Shufflon-specific DNA recombinase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: PLK5_HUMAN
Sequence: MYTVLTGTPPFMASPLSEMYQNIREGHYPEPAHLSANARRLIVHLLAPNPAERPSLDHLLQDDFFTQGFTPDRLPAHSCHSPPIFAIPPPLGRIFRKVGQRLLTQCRPPCPFTPKEASGPGEGGPDPDSMEWDGESSLSAKEVPCLEGPIHLVAQGTLQSDLAGPEGSRRPEVEAALRHLQLCLDVGPPATQDPLGEQQPILWAPKWVDYSSKYGFGYQLLDGGRTGRHPHGPATPRREGTLPTPVPPAGPGLCLLRFLASEHALLLLFSNGMVQVSFSGVPAQLVLSGEGEGLQLTLWEQGSPGTSYSLDVPRSHGCAPTTGQHLHHALRMLQSI
What is the function of this protein?
Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
What are the official names of this protein?
Inactive serine/threonine-protein kinase PLK5, Polo-like kinase 5, PLK-5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm.
Protein: RL18_LYSTE
Sequence: MGIDINHKYDRKVRRTEPRSQDIYLRLLVKVYRFLARRTNSKFSRIILKRLFMSRINLPPISLARVCRFMKKESRKNSIAVVVGTITDDARIFEIPKLKVCALRITEKARGRILKAGGEIITFEKLAEISPTGNKTVLMQGRRNAREAVKHFGPAPGVPHSHTKPLVRSKGRKFERARGRRKSCGYKK
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_XANOR
Sequence: MTIELKPGGLLIAIEGIDGAGKTTLARRLTTTLEAAGARVVLSKEPTNGPWGTKLRQSAATGRLSADEEAELLIRDRHEHVDTLIAPALARGDIVILDRYFPSMVAYQGAAGLPLDELLELNAFAPRPDVLLLLDLPPPTGLARIRARGDAPNHFETQDNLERCRTIFAGLELPGKHVVDASADADSVLRQAHAIIVAALADRLSGDGAPADTGKAALELLSAGRPA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SYG_METM5
Sequence: MDKYDKIIDLTKRRGFLWNSFEIYGGIAGFFDYGPLGAILKNNVINTWRKHYIVNEGFYEIDSPTVTPYEVLKASGHVENFTDPLVECKSCLESFRADHIIEENVDVDTEGKTLQELQEMIEKNNIKCPKCGGEFKEVSTFNLMFATSIGPGGKRAAFMRPETAQGIFIQFKRISQFFRNKLPFGAVQIGKAYRNEISPRQGVIRLREFTQAEGEFFIDSRKKENFEKFESVKEIVLPLLSGKNQENESLSAEEKIVRMSLSDAVKNGIIAHEAIAYYIAVTKKFLMEIGIDESKLRFRQHLPNEMAHYAADCWDAELYTDRYGWIECVGIADRTNYDLLAHMKNSSEDLSVFVELDEDKEIEVYEIELNYKLVGRTFKGDSKVLEESLKELDDKKMEELVEALETEGKYVLSTCKRDFELLKEYLTAKKVKKTVKGEKIIPHVIEPSYGIDRITYCVMEHAFKEDEDRTVMGFSNAVSPIKVGVFPLVNKEGMPEIAMDLKNKLRENGLIAEYDDSGAIGRRYMRMDEVGTPFCVTIDGETLTDSSVTIRERDSREQFRIPINEVVPYIKDKLN
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA2_PHYPA
Sequence: MAMAAAAAVASQGLLATSSQQQKKSSAKLICNAATFFSGKRLLWVKSCNNGAVGLRASGVRCEAQAIEREAVKADAGNSREEDAFSGLKQVCAVLGTQWGDEGKGKLVDILAQRFDVVARCQGGANAGHTIYNDKGEKFALHLVPSGILNEKTTCVVGNGVVIHLPGFFKEIDNLESKGVNTNGRLLVSDRAHLLFNLHQEVDGLREAELAGQMIGTTKRGIGPCYASKAIRNGIRVSDLRHLDTFREKLDILYRDAAARFKDFEYSSDEVNAEMEKYVKYAERLEPYIVDTVDYVNAAIAEGKRILIEGGQATMLDIDFGTYPFVTSSNPSVGGICTGLGVAPNRLGDIVGVAKAYTSRVGSGPYPTELFGEEGDELRKAGFEWGTTTGRPRRCGWLDIVALNFVCTINGFTAINLTKLDVLSGLPEVKLGIAYKTPSGEKLRAFPADLSILEQVEVEYEILEGWKEDITKVRSYDELPAAAQRYVERIEELIGLPCQYIGVGPGRDALIVKQ
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase 2, chloroplastic, AMPSase 2, AdSS 2, IMP--aspartate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPAR_HUMAN
Sequence: MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT
What is the function of this protein?
Acts as a receptor for urokinase plasminogen activator.  Plays a role in localizing and promoting plasmin formation.  Mediates the proteolysis-independent signal transduction activation effects of U-PA.  It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
What are the official names of this protein?
Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3.
What are the subcellular locations of this protein?
Cell membrane. Cell projection, invadopodium membrane. Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin- dependent manner. SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: GLPB_VIBCH
Sequence: MMHYDVAVIGGGIAGYSAALRALQAGKKVVLINQGQSALHFSSGSIDVLGRLPDGSVVNQPFDALSALQQQAPEHPYSKVGRKNSEKGLMWFKRTLDSAHVPLHHEPDGANHWRITPLGTLKNTWLSQPFVYPYRGNADFSRIMIVAIDGYRDFQPAMLRDNLAQRPELANTPMLTVNVSIPGFEGFRRNPNELRSIDIARLLRQESAWNALCDQLMRVARPDDLVIMPAIMGNGDGLHLMSKLQQVTQLRFHEVPTMPPSLLGIRIEEALHRSFIQGGGVQLKGDKVIGGNFAGSRLTAIHTQNLRDFPISAEHYVMATGSYFSQGLQASQHAIQEPIFALDVQQNPDRAQWRHAQFIAAQSHPFMTFGVTTDANLHPSRQGKTIDNLWCCGAMLSGYDPVFEGCGGGVAIATAYHAVEQILATYAQTKQPEVLL
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: LEXA_HAEIG
Sequence: MRPLTARQQEVLDLLKRHLETTGMPPTRAEISRELGFKSANAAEEHLKALSRKGAIEIIPGASRGIRILDNSSNDEFDGLPLVGRVAAGEPILAEQHIEATYRVDADMFKPQADFLLKVYGLSMKNVGILDGDLLAVHSTKDVRNGQIVVARIEDEVTVKRLEKKGSIIYLHAENEEFDPIVVNLEEQKNFEIEGIAVGIIRNNAWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: BIM3_ARATH
Sequence: MNSHDIDDQLEADVYSNLPSRNDSSTGRRNRNSCRSKHSETEQRRRSKINERFQSLMDIIPQNQNDQKRDKASFLLEVIEYIHFLQEKVHMYEDSHQMWYQSPTKLIPWRNSHGSVAEENDHPQIVKSFSSNDKVAASSGFLLDTYNSVNPDIDSAVSTKIPEHSPVSAVSSYLRTEPSLQFVQHDFWQPKTSCGTINCFTNELLTSDEKTSASLSTVCSQRVLNTLTEALKSSGVNMSETMISVQLSLRKREDREYSVAAFASEDNGNSIADEEGDSPTETRSFCNDIDHSQKRIRR
What is the function of this protein?
Positive brassinosteroid-signaling protein.
What are the official names of this protein?
Transcription factor BIM3, BES1-interacting Myc-like protein 3, Basic helix-loop-helix protein 141, AtbHLH141, bHLH 141, Transcription factor EN 127, bHLH transcription factor bHLH141.
What are the subcellular locations of this protein?
Nucleus.
Protein: YUNC_BACSU
Sequence: MVNLTPIMIEGQPFTAVTVKLPKTNFMAVANDHGYIMCGALDVALLNEKLKERGIVAGRAVGVRTIDQLLDAPLESVTYAAEDLGIKVGMSGREALLKMMK
What are the official names of this protein?
Uncharacterized protein YunC.
Protein: CFI_MAIZE
Sequence: MACRRWWSTAVVFPPVARPPGSAGSHFLGGAGVRGVEIGGNFIKFTAIGVYLEDAAVPALAKKWGGKTADELASDAAFFRDVVTGDFEKFTRVTMILPLTGEQYAEKVTENCVAFWKAAGLYTDAEGVAVEKFREVFKPETFAPGRSILFTHSPAGVLTVAFSKDSSVPAAGGVAIENKRLCEAVLESIIGERGVSPAAKLSLAARVSELLAKETAAAADAPQAEPVSITA
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: NU2C1_ACOAM
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDRPWFYFISSTSLVMSIAALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDSITIFVAPECFSLCSYLLSGYTKRDVRSNEATMKYLLMGGASSSILVHGFSWLYGLSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFARIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MNHC2_STAAC
Sequence: MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGTYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK
What are the official names of this protein?
Putative antiporter subunit mnhC2, Mrp complex subunit C2, Putative NADH-ubiquinone oxidoreductase subunit mnhC2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DER_ALISL
Sequence: MIPVVALVGRPNVGKSTLFNRVTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGIDGTEEGVETKMAEQSLAAIEEADVVLFMVDGRAGLTSSDEAIAKHLRSREKPTFLVVNKIDGIDADAASAEFWQLGMSKVYQIAASHGRGVTSLLELALAPFMEELVEESLRDENGEITDLTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLINRILGEERVVVYDMPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAIEDANVVLLVIDARENISDQDLSLLGFALNAGRSLVIAVNKWDGLNNEVKEKVKSELDRRLGFVDFARLHFISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRVMKMAQDDHQPPMVRGRRVKLKYAHAGGYNPPLIVIHGNQVKELPSSYKRFLMNYFRKSLEIMGTPIRIQFQNSENPFEDRGGKLTLSQERQRKRLVGAVKNRNKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CVC2_HCMVM
Sequence: MSLLHTFWRLPVAVFFEPHEENVLRCPERVLRRLLEDAAVAMRGGGWREDVLMDRVRKRYLRQELRDLGHRVQTYCEDLEGRVSEAEALLNQQCELDEGPSPRTLLQPPCRPRSSSPGTGVAGASAVPHGLYSRHDAITGPVAAPSDAVAASAAAGASSTWLAQCAEQPLPGNVPNYFGITQNDPFIRFHTDFRGEVVNTMFENASTWTFSFGIWYYRLKRGLYTQPRWKRVYHLAQMDNFSISQELLLGVVNALENVTVYPTYDCVLSDLEAAACLLVAYGHALWEGRDPPDSVTAVLSELPQLLPRLADDVSREIAAWEGPVAAGNNYYAYRDSPDLRYYMPLSGGRHYHPGTFDRHVLVRLFHKRGVLQHLPGYGTITEELVQERLSGQVRDDVLSLWSRRLLVGKLGRDVPVFVHEQQYLRSGLTCLAGLLLLWKVTNADSVFAPRTGKFTLADLLGSDAVAGGGLPGGRAGGEEKGYGGRHGRVRNFEFLVQYYIGPWYARDPAVTLSQLFPGLALLAVTESVRSGWDPSRREDSAGGGDGGGAVLMQLSKSNPVADYMFAQSSKQYGDLRRLEVHDALLFHYEHGLGRLLSVTLPRHRVSTLGSSLFNVNDIYELLYFLVLGFLPSVAVL
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.  Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
What are the official names of this protein?
Capsid vertex component 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RS2_LYSSC
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMKKYIFVERNGIYIIDLQKTVKKLEEAYDFMRQVGQDGGKVLFVGTKKQAQEAIKDEAERSGNYYINQRWLGGTLTNFGTIQKRVARMKQIEKMEEEGTFEVLPKKEVIQLKKEHERLIKFLGGIRDMHDLPDVMFVVDPRKERIAVAEARKLNIPLVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMADALIESKQGEEEAPAVEAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y1590_PASMU
Sequence: MKKLFLASSFADVFDLFLDFAGNIQNKSITFIPTASKVEEVKFYVDDARNAFLQQGAFIDELDLSTASLAEITDKLAKNEMIYVSGGNTFFLLQELTRTGTAQLIQQHIQAGKMYIGESAGAMISAPNIDYVKYMDSLDQAPMLRDFTALNLVDFYVVPHYTNFPFVEAAQKIIDTYSTTLPLQPIDNHQAILVNNETKIIRGNHKG
What are the official names of this protein?
Uncharacterized peptidase PM1590.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
Protein: ISPE_BORPA
Sequence: MTLYDVPAPAKLNLFLHVVGRRADGYHLLQTAFRFIDLADTLHFEARADGAIGRAYELPGVAESDDLVVRAARSLQRATGTRQGAQIGLHKRIPQGGGLGGGSSDAATTLIALNRLWGTGLSRSQLMQLALPLGADVPVFVFGQSAFAQGVGEDLTAVALPPAAYLVVQPDAGVPTAAIFSDPDLTRDCASVTIADFLALLTSCFGRNDLEPVVLRRYPEVSGAVRWLFEHGLRVRMSGSGACLFAEFPTLPEAVLAQEEITATMRVAGKTTSHTHPGFRLVQASTGLTEHPLRNWIAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: METN_XYLFT
Sequence: MIQFKDSYKHYGANGREVTALQPLNLEIRAGEVFGIIGHSGAGKSTMLRMINRLEEPSGGHLLINGQDITVLDRMGLRALRRQIGMIFQHFNLLSSYTVAGNVAFPLKLTGASDAKINARVAELLAWVGLEAHANTYPAQLSGGQKQRVGIARALATRPQILLCDEVTSALDPQTTSTVLQLLARINRELGLTIVLITHEMDVIRRICDRVAVLDTGRLVEIGLVTDVFLHPQHPTTRSFVMETEHIDTSALDQDFALVKGRIVRLTFIGTDTYLPLLGRVARETGVDYNILSGRIDRIKETPYGQLTVALSGGDPVAAQAAFAAAGIHIEELRA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VSP1_BPMV4
Sequence: DPRFNPKYPTIYDYGYGTPAGTLGINCMHELYPYVEGVTINRQKHYDEQEAIRNGEIQQMQRYYERQVRKWKQRKLAAERIGNTNLEAKCSSAIRRYQSKIRKIVSENDFLTRQYDREKIANI
What are the official names of this protein?
Structural protein, ORF1 protein, ORF371.
What is the protein family that this protein belongs to?
Belongs to the Lactobacillus delbrueckii bacteriophages ORF1 protein family.
What are the subcellular locations of this protein?
Virion.
Protein: CD48_HUMAN
Sequence: MCSRGWDSCLALELLLLPLSLLVTSIQGHLVHMTVVSGSNVTLNISESLPENYKQLTWFYTFDQKIVEWDSRKSKYFESKFKGRVRLDPQSGALYISKVQKEDNSTYIMRVLKKTGNEQEWKIKLQVLDPVPKPVIKIEKIEDMDDNCYLKLSCVIPGESVNYTWYGDKRPFPKELQNSVLETTLMPHNYSRCYTCQVSNSVSSKNGTVCLSPPCTLARSFGVEWIASWLVVTVPTILGLLLT
What is the function of this protein?
Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation (PubMed:27249817, PubMed:12007789).  Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex (PubMed:19494291).  In turn, promotes LCK phosphorylation and subsequent activation (PubMed:12007789).  Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells (PubMed:9841922, PubMed:27249817).
What are the official names of this protein?
CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, SLAM family member 2, SLAMF2, Signaling lymphocytic activation molecule 2, TCT.1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
Protein: KHSE_STRP7
Sequence: MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQIGKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLGQLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIPNYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYRQDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHDLRVDTQGVRVEAK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR2_MANKU
Sequence: ADYLQLARA
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-2, FMRFa-2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYP_NEIMF
Sequence: MKASQFFISTLKEAPAEAALASHKLMIRAGLIKANASGLYTWMPMGLRVLRKVENVVREEMARAGSVELLMPVVQPAELWQESGRWEFYGKELLRLKDRHDRDFCMGPTCEEVIADIVRKEINSYKQLPKNFYHIQTKFRDEVRPRFGVMRAREFVMKDAYSFHADYASLQTTYDAMYDAYCRIFTRLGLAFRPVAADTGSIGGTGSHEFQVLAESGEDVIAYSDTSDYAANIELAPTLPLKGERTAAQAELTKVHTPNVKTIESLVEFLNIPVEQTLKSIVVESENEGEIVLLLLRGDHEFNDIKAEKLAGVKSPLTMASSAAIVEQFGANGGSLGPVGFKGKVYADFATEKGADWVIGANEDGYHYTGFNFGRDAAEPEFVDLRNVVEGDESPDGQGRLKLARGIEVGHVFQLRDKYTQAMNVSFLDNNGKSQIMEMGCYGIGITRVVAAAIEQNNDEKGIIWTKAMAPFEVVIVPMNYKKSDAVREAADKIYAELLAAGADVLLDDRDERAGVLLNDSELLGIPHRIVIGDRALKEGNVEYAERRNNEAQAVAIGEIVARVTASLNG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_SULIM
Sequence: MRNINVQLNPLSDIEKLQVELVERKGLGHPDYIADAVAEEASRKLSLYYLKKYGVILHHNLDKTLVVGGQATPRFKGGDVIQPIYIVVAGRATTEVKTESGIEQIPVGTIIIESVKEWIRNNFRYLDAEKHLIVDYKIGKGSTDLVGIFEAGKRVPLSNDTSFGVGFAPFTKLEKLVYETERHLNSKQFKAKLPEVGEDIKVMGLRRGNEVDLTIAMATISELIEDVNHYINVKEQAKNEILDLASKIAPDYDVRIYVNTGDKIDKNILYLTVTGTSAEHGDDGMTGRGNRGVGLITPMRPMSLEATAGKNPVNHVGKLYNVLANLIANKIAQEVKDVKFSQVQVLGQIGRPIDDPLIANVDVITYDGKLNDETKNEISGIVDEMLSSFNKLTELILEGKATLF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: RECR_FRAP2
Sequence: MNNQIFSPKITAVIESLRKLPTIGKKSSQRLALYLLDKSPETAITIANSLLDAAENIKKCKYCQSLTEKDVCDICGSQNRDESKLCIIESMLDLVAIEEAGFFKGKYFVLNGRISPLDGIGPNELKLDILEQIIINREINEIILAISPTVEGETTAHFISQMIGKDIKISRIGFGVPFGGELEYLDQQTLIHAFNARTNIK
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RS8_ERWT9
Sequence: MSMQDPIADMLTRIRNGQSANKVAVTMPSSKLKLAIANVLKEEGYIEEFKIEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL1_BRUA4
Sequence: MAKISKRINKIREGVDRNKLYDLSAAIGLVKERAVAKFDETIEIAMNLGVDPRHADQMVRGVVNLPNGTGRTVRVAVFARGDKAEEAKKAGADIVGAEELFEIVNGGKIDFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTTDVAAAVAASKGGAVEFRVEKAGIIHAGIGKVSFDNAKLEENIKAFADAVIKAKPSAAKGEYVKRVSLSSTMGVGVKVDPATVKVVA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: S46A3_MOUSE
Sequence: MKISFIEPAILLNAFAMTLTIPLTAQYVYRRIWEETGNYTFASNSNGSECDQNKSSSIFAFREEVQKKASLFNLQVEMSALIPGLVSTFMLLASSDNHGRKLPMVLSSLGSLGTNTWLCMMSYFDLPLQLLIASTFIGALFGNYTTFWGACFAYIVDQQKEYKHRIIRIAILDFMLGVVTGLTGLSSGYFIRELGFVWSYFITAMVLIVNLAYILFFLNDPIKESSSQIVTMSCIESLKDLFYRTYMLFKNGSSKRQALLCLLIFTLVIYFFVIIGISPIFTLYELGPPLCWNEVYIGYGSALGSVSFLSSFLGIWLFSYCLKDIHIAYIGIFTTMVGMTLAAFTRTTLMMFLVRIPFIFTIMPLSVLRSMLSKVVHSTEQGALFACIAFLETLAGVTSTSAYSGIYSATVAWYPGFIFLLSAGLLVLPAISLCCVKSIGWEEGSYTLLVHEEPSEHTSD
What are the official names of this protein?
Solute carrier family 46 member 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SLC46A family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS19_RICPR
Sequence: MARSIWKGPFVDGYLIKKVQKLMKSGKSEMIKTWSRRSTILPIFVGFTFSVHNGNKFIPVYINEEMVGRKLGEFAPTRTFHGHGADKKVKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.