PharMolix/UniProtQA huggingface dataset:
Protein: MSTO1_BOVIN
Sequence: MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALCRPTDAKEPPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLSSLKQEGGLYRDKQLDAAIAWQGKLTTHKEELYPKNPYLQDLLSAEGVLSSDGTWRVKSIPNGKGLPPFTNAITPKPVMPTEGSIRVWSDFLRVHLHPRSICMIHKYNHDGEAGRLEAFGQGESILKEPKYLEELEDRLHFYVEECDYLQGFQILCDLHDGFSGLGAKAAELLQDEYSGRGIITWGLLPGPYRLGELQKNIYRLLNTAFGLVHLSAHSSLVCPLSLGGSLGLRPEPPVSFPLLQYDATLPFHCGAILATALDTVTVPYRLRSSPVSMVHLADMLNFSGKKVVTAGATIPFPSVPSQSLPDTLMQLGEATPWTPLSACGDPSGTCCFAQSVVLRGLDRAHHTSQLAPGTPLPSPLHACATGEEVLAQYLQQQQPRVRSSSHLLLTPCKVVPPYPSLFSSSLSQHGSVLDGLPTGTAVESIPVLGALCSSSSLNRALGDLAKDLSKLDLRRWASFMDAGVEQDDLEETLQDLRSLAQCYEGGDDRLVD
What is the function of this protein?
Involved in the regulation of mitochondrial distribution and morphology.  Required for mitochondrial fusion and mitochondrial network formation.
What are the official names of this protein?
Protein misato homolog 1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Cytoplasm.
Protein: RL23_BACCQ
Sequence: MRDPRDIIKRPVITERSMEMMAEKKYTFDVDVKSNKTEVKDALEAIFGVKVEKVNIMNYKPKAKRVGRHAGFTSRRRKAIVKLTADSKEIEIFQGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y8605_DICDI
Sequence: MNQDFEHQLSFHSNNNSNSNHHHSYNNSINSGSSSSGSNNSSNNNSFNDEIEGGEIQEEPYISSSSIRTSELDQKILFLSKDRNLSKRTGSEDPQYGSFFNTLSEPLILSQQSHQQHKKQNRDQHSSSSSSSSSSSSSSSRSKRSNQPPPLVGIAAINQQQQHLQKQKQQLQQQQIQIQLQKQQLQQQIVQHQTELQNKSTPSKTSSASSPPQNTLSAPAPPAPAPTSAPTSAPTSSSVSSLTQPQKPKSVQYSQPAPLEIREEKVDPNIKEEFENTESKISSIIQSMICPISPLRSPFNESIVYTNISSSSSDFDYNNSNSNNSNNNNNNNNSITENNTDKMINNQPSSTNSKKLKTNEIDSKDTSNNNLNGADFKKTTTTTTTTTTSSTSEPIKSPNSSSSTNSSASTTPTVKKEKLILKIPKLVVKSDSGTNKESNSSNSSSTTSTPKSKDLEEKKEKEKSEKEKGEKLEKSEKSDKSEKTEKTEKAEKTEKSEKSEKSEKTDQLEKAEKLEKEEKTEKKKTEKVEKAGKVEKKEKPKDKQTKQEKEKEKEKEKETEKEKEKKDKVSSKKDELQPIEEDKKKIGGKRKSINSSKPEFKSDSIDMDIDEPNPKSSSNYNDSDDDSENEIDKSDKRSQKKSKVESPPKSSKLSNGKDKKSTTTTTTSTSSSSSLPSLSSSSSSLPLPSSSSSSSSSSSSSSSSSSSSSSSSSSSTTSTKIKKEEPPPPPPQQPPPPPPQQPPPPPPPINPFSVSEHDKKIIEKETGKDLGSSRDRDNSSRTTNGRDSDRDRDSREGSRDRDRDRDRDRDRDRDRDRDRGRDRGNGDRGEGDRDRDRSGRSDRDRDRDRDRDRDRDRDRDRGNDRDRDRDRDRDRDRGRDRGSDRDRDRKDSNSNNNSNNNNNNNNNNNNNNNNNNNNKKDNNNNNNNNNNNNNKRDGNKDGSSSELTPKKTKQEEKLIRSQIDQIKEDAKDLKKLAKELQSKNQNECLEMYLQVGLKYLLTTHYMIEVNDPLPNIISFLSEISLFFSNTSRLALHFKDDPKASLCFKCESFCCIKMFCLKKDNLKHTRKEVSSVYSSFLPNSSSSSKSSSSSSSSSNQPANPATAPLTPNPGNPSESPSQASSSSNPTSTTPSATTTTTTTATTTPSTTATTTTTSNNNQPNTSHVNTKIAQYFKDTEDIFRGMDAWEKSILHSNIPGFHFNFFYQPYLEFIDQVKKESDKQS
What are the official names of this protein?
Uncharacterized protein DDB_G0284459.
Protein: CUTI_MONFR
Sequence: MKTSAQQLLSLLLLPLSAIAAPTGEIEARACSTVTVIFARGTTETPTLGTVIGPQFLAALKSSFGGSVTMNGVPYAADVPGFLKGGDPTGSKVMANMVSSALSSCPNTKLVISGYSQGGQLVHNAAKQLPAATTAKIAAAVIFGDPDNGSPVQGVPAAKTKIICHAGDNICQHGSMILMPHLTYGMDATAAAAFVKQVAGS
What is the function of this protein?
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (By similarity).  Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity).  Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (By similarity).
What are the official names of this protein?
Cutinase, Cutin hydrolase.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ST1A3_HUMAN
Sequence: MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.
What are the official names of this protein?
Sulfotransferase 1A3, ST1A3, Aryl sulfotransferase 1A3/1A4, Catecholamine-sulfating phenol sulfotransferase, HAST3, M-PST, Monoamine-sulfating phenol sulfotransferase, Placental estrogen sulfotransferase, Sulfotransferase 1A3/1A4, Sulfotransferase, monoamine-preferring, Thermolabile phenol sulfotransferase, TL-PST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCR_ECOSE
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRIQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: IRS1B_XENLA
Sequence: MASPTDPQAQENFSDVRKVGYLRKPKSMHKRFFVLRAASESSLARLEYYENEKKWRHKSGAPKRSIPLESCFNINKRADSKNKHLVALYTKDECFAIAAECEQEQEGWYQALVDLHNRGKTHHQHHNHDGAVNGVHDGLNGDEVYGEVTPPGLAFKEVWQVIMKPKGLGQLKNLVGIYRLCLTNRTISLVKLNSDAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGAGEFWMQVDDSVVAQNMHETILEAMKALSDEFRPRSKSQSSSNCSNPISVPLRRHHLNHPPPSQVGLNRRARTESATATSPAGGAAKHGSSSFRVRASSDGEGTMSRPASMEGSPVSPSASRTQSHRHRGSSRLHPPLNHSRSIPMPATRCSPSATSPVSLSSSSTSGHGSTSDCMCPRRSSASISGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSMGHTPPAREEELNNYICMGKSSSHLQRGPQQRYQPSRGEELTDFDKVFRKRTHSSGTSPPTVSHQKTPSQSSIEEYTEMMPTHPVRLTSFRHSAFVPTYSYPEECLDLHLEGSRANHKDDGYMPMSPGVAPVSTKTNDYMPMSPKSVSAPQQIINPRWHSAVDSNGYMMMSPSGSCSPDNTNYSKIWTNGTNPKLSIDSIEGKLPCSDYINMSPASGSTTSTPPDSYLNSVEESTKPVYSYFSLPRSFKHVHRKSEDGNLRISANSGHNLYTEDSSSSSTSSDSLGGQDPQQPRKGEGCIQGKRLTRPTRLSLENSSKASTLPRVREPALPPEPKSPGEYVNIEFNDKVFSGGLVPSMCSLPFVQSRVVPQRENLSEYMNMDLGVWRAKTSYASTSSYEPPNKPVNSVCPTETCSSSRPPIRGKPISRDYMSMQLGSLCPDYSQVPPTRLSAKSITLSSSKSNYAEMSSGRVSDNIPAIAPASNSSLSEASRSSLLGQGSGPSAFTRVSLSPNRNPSAKVIRAGDPQGRRRHSSETFSSTPTTARVTTGPVSGEDVKRHSSASFENVWLRPGEIARRDSLQPSDHTHNGLNYIDLDLAKDLSSLDHCNSHQSGVSHPSDDLSPYASITFHKLEEHRSQAETEE
What is the function of this protein?
May mediate the control of various cellular processes by insulin.  When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or grb2.  Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
What are the official names of this protein?
Insulin receptor substrate 1-B, IRS1-B, xIRS-1-B, XIRS-L'.
Protein: RL28_LEPBA
Sequence: MARTCVVTGKGTTAGNNVSHSHKKNRRIWKVNVITKKIFLEDENRWVRVKISTRALRTLRKKGLKVAIKDHGGDITAITPKKYVGITPKAQPVATA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: HEMA_I83A5
Sequence: MERTVIALAIISVVKGDQICIGYHANNSTKQIDTIMEKNVTVTHAQDILEKKHNGKLCSLKGVKPLILKDCSVAGWLLGNPMCDEFLNAPEWSYIVEKNNPINGLCYPGDFNDYEELKHLVSSTNLFEKIRIIPRNSWTNHDASSGVSSACPHLGRSSFFRNVVWLIKKNNVYPTIKRTYNNTNVEDLLILWGIHHPNDAAEQAKLYQNLNAYVSVGTSTLNQRSIPKIATRPKVNGQSGRMEFFWTILRPNDTISFESTGNFIAPEYAYKIVKKGDSAIMRSELEYGNCDTKCQTPLGAINSSMPFHNVHPLTIGECPKYVKSDKLVLATGMRNVPQKKKRGLFGAIAGFIEGGWQGMVDGWYGYHHINGQGSGYAADKKSTQKAIDGITNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFIDVWTYNAELLVLMENERTLDLHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYNYPKYSEESKLKRKEIDGIKLESMGTYQILSIYSTVASSLALAIMVAGLSFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RBFA_HAEIE
Sequence: MAREFKRSDRVAQEIQKEIAVILQREVKDPRIGMVTVSDVEVSSDLSYAKIFVTFLFDHDETAIEQGMKGLEKASPYIRSLLGKAMRLRIVPEIRFIYDQSLVEGMRMSNLVTNVVREDEKKHVEESN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_METCA
Sequence: MASFPELSERAQQLLKALVERYIGEGQPVGSRVLARDAGLSPATIRNVMADLEELGLITSPHTSAGRLPTVSGYRLFVDSLLTVKPLHQAIVDQLWLDLESRENPRDLLETASKLLSELTHMACIISMPRRETLVFQHIEFLPLSDNRVLAILVTSDQEIHNKIIHTPHKFSAAELQTAANFFNAVCGGKDMVSAREHLRAELAKERDRLSEQLLQAGEIAEQALAEGGRSRKPFLVRGETNLMDFVELADVDRLRGLFEAFRQKESIVGLLDRCLESPGVKIIIGEESGFRPLEPCSLVTASYSVDNRVMGVLGVIGPTRMKYERVIPLVDVTAKLVGAALNQRTLAPT
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: MI43_MYCIT
Sequence: MSASCAVPRLTRFAVFAVAGATALSLSACGSSNKSSSTSTSTSTSTSTVTSAAPSSTPNAEAKVSGLIASVAGNSIQVTKEDNATAAVNFTSATKITEAVPAGLPDVTQGSCLIVKPTEGSAPGQPVTAAKVKISESVNGTCPKPHESTPGGASSTPPSGSPSPAPAKPAWVRGSVASVSGDTINLTGTDASGNTTQTTVTVDDKTKYTKQTTANTEAIAPGKCLSARGTTDSGGALQATSIKLRQAVDGKCGKPKQPGQGG
What are the official names of this protein?
27 kDa lipoprotein antigen, Mi43 antigen.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS19_CLOAB
Sequence: MSRSIKKGPFVKESLLNKIVEMNKAGDKKVVKTWSRSSTIFPEMIGHTIAVHDGRKHVPVYISEDMVGHKLGEFVLTRTFRGHGNTEKTTSVK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ANMK_PSEF5
Sequence: MALYIGVMSGTSLDGLDIALIEQSPALRLVATRYIPMPDTLRAELLGLCASGPDEIARSAIAQQHWVELAAQGINQLLQQQQLPPQDIRAIGSHGQTVRHEPSRGFTVQIGNPALLTELTGITVVSDFRSRDVAAGGQGAPLVPAFHEALFDQRPGNRAVLNVGGFSNLSLIETAKPVAGFDCGPGNVLLDAWIQAQRAENFDRNGQWAASGQVDPPLLQALLSDPFFATQGPKSTGREVFNLDWLQRHLRARGAIAAENVQATLLELTALTIVESLQSAQSDTQELLVCGGGAHNAALMGRLAALLPQTRVSSTAAYGVDPDWVEAMAFAWLAHCCLEGIAANRPSVTGARGLRVLGAIYPA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: TUSA_KLEP3
Sequence: MSELFSTPDHTLDALGLRCPEPVMMVRKTVRTMPVGETLLIIADDPATTRDIPGFCRFMEHELVAQETEALPYRYLIRKSH
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_LAWIP
Sequence: MFAKLENLEQKFIEIECSLAQPNIFNDQEQYRKLTKTHSDLKPIVTTFQQFKKLQQQLSENKELISDIDPDIQEMALEEIKKLELELTHLEYELKILLLPKDPLDEKNILLEIRAGTGGEEAALFAADLFRMYCRYAEKMHWKVEIMSQSDSDTGGFKEIIALIQGDNVYSRLKFESGTHRVQRVPTTESQGRIHTSAATVAVLPEAEDVDIEIRPEELRFDVFRSSGPGGQSVNTTDSAVRVTHIPTGIVVTCQDEKSQHKNKAKALKVLSSRLLQIKQEQQEIEQADARRALVGSGDRSERIRTYNFPQGRVTDHRINLTLYSLIKVMEGEIQEFIDALSTHAQTEALKMQATQIAS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_CHLPM
Sequence: MFLTDGSSLNSLTMTRRMMVGKRVRTRFAPSPTGYLHVGGLRTALYNYLFAKRMDGDFVVRIEDTDQSRKVADAQENLIKTLEWAGLMPDESPLHGGDFGPYLQSERLDIYKKYCEQLLEAGHAYHCFATSEELEENRQLQLKQGLQPKYNRKWLPEDMGGSMPRSEIQKKLDEGVPSVVRMKVPDYVSVWFEDIIRGPIEFDSATIDDQVLMKSDGFPTYHFASVIDDHLMEFTHIIRGEEWLPSMPKHLLLYEFLGWEPPKYAHLPLLLNPDRSKLSKRQGDVSVEDYIRKGYSGEAIVNFVALLGWNQGEGCEQEVYSLQELTERFSLERVGKAGSIFTIDKLNWLEKQYIKNRPAEDIIRVIKPLLLSELEKKETLLDPATITGERYLEDVIELMRERVGFEREFVTFSSYFFFEPETYEEDAVKKRWTPDTNSLLDEFLPVLESMPDFTAEAIEAALKEFVAPKGLKAAALIHPLRIVSSGVSFGPSLYHMLEVLGREAVVRRIRKGMAVITLPQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCEM_RHORU
Sequence: MSEYQNILTGVQVRTAPHSAPIAKGIFPRLGKPGFSYWLGKIGDAQIGPIYLGTTGVLSLVFGFFAIEIIGFNLLASVNWSPMEFGRQFFWLGLEPPAAEYGLGFAPLAEGGWWQIAGFFLTTSILLWWVRMYRRARALKMGTHTAWAFASAIFLFLSLGFIRPLLMGNFSESVPFGIFPHLEWTNSFSLNYGNFFYNPFHMLSIAFLYGSALLSAMHGATILAVSRLGGDREVEQITDRGTAAERAALFWRWTMGFNATMESIHRWAWWFAVLCTFTGAIGILLTGTVVDNWFEWGVKHGLAPAP
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein M chain, Photosynthetic reaction center M subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Multi-pass membrane protein.
Protein: TBP_MACFA
Sequence: MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQTTQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPVTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.  Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III.  Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription.  The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter.  SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOG2B_XENLA
Sequence: MWIHFAPLRIPFSRRLQTVAVLQWAVSFLAMAQCCIALYILLLFSRYWFLALLYGVWLYLDWDTPSKGGRRSNWVRSWIVWKYFAEYFPIKLLCTAPLDPKYNYIMGFHPHGVLVVGAFGNFCTEGTGFSRLFPGLTPHLLMLPAWFRVPFFREYIMSGSLVSSDRSSAHYLLSQKSGGQALVIAVGGPPEALDAKPGELTLQLLNRTGFIKMALTHGAHLVPVLSFGENDLYNQVNNPRGSLLRTTQEKLQKVLGIALPLFHGRGVFQYSWGLLPHRRPIYTVVGSPIPVAKTPCPTQEQISSLHALYVAKLRELYTTHKGNYGIPRDRSLVLC
What is the function of this protein?
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA.
What are the official names of this protein?
2-acylglycerol O-acyltransferase 2-B, Acyl-CoA:monoacylglycerol acyltransferase 2-B, MGAT2-B, Monoacylglycerol O-acyltransferase 2-B.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region.
Protein: RSMH_MAGSA
Sequence: MSPQPHIPVLLAEVIAALAPRNDGVYLDGTFGAGGYSRAILAASACRVWAIDRDPTAVARGKLLEEGSAGRFSMIEGRFGDMDSLLRQQGVNQVDGIALDIGVSSMQIDQPERGFSFAKDGPLDMRMETKGPSAADMVNDTPETELANIIYRYGEERLSRRVAKAIVEARRLKRFERTGELAEVVRKVVPRSGDGIDPATRTFQALRIAVNDELGELERGLEAAERLLAPGGHLAVVTFHSLEDRVVKSFLKARSGEAARPSRHVPQAQGSGPAASFALLSRKAIGPAPDEARANPRARSAKLRAAARTAAPAWETVS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_DELAS
Sequence: MADSCTMTTDLNIPLFERAKAVIPGGVNSPVRAFNAVGGTPRFVRRAQGAHFWDENAQQFTDYIGSWGPMILGHGHPEVMAAVQAAALEGFSFGAPTEREVVLAEKILSLMPSMDMVRMVSSGTEAGMSALRLARGFTGRNKIIKFNGCYHGHADALLVKAGSGLATFGASSSAGVPQDVVKDTVVLEYNDVGQLEEAFAQFGDQIACVIMEPIAGNMNFVRASVPFTRRIRELTREHGALMVYDEVMTGFRVALGSAQSLYAQHIEGFAPDITVLGKVIGGGMPMAAFGARREIMEKLSPLGPVYQAGTLSGNPIATACGLKTLELISEPGFHDALHAKTGRLMAGFKAEADAAGVPFSVDHQGGLFGFYLLPELPSTWTEVMKTDGARFNRFFHGMLERGHYFAPALYEAGFVSAAHTDADIDKTIEAAREVFKTL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIL_SYNE7
Sequence: MSDRSLSELGEQGLLPLLQAFCPAEQRGDDAAILTPPAGQQLVVSSDVLVEGIHFSEATTPPAAIGWRAAAANLSDLAAMGATPAGITLALALPSDRRLSWLQQIYQGLDRCLKQYDCPLIGGDLSRSPTATLAVTALGWVNPNRVIRRSTAQVGDWIMATGTHGLSRLGLGHLLGEWTLAEPLRDQAIAAHQAPKPRLDVVPLLARSQPAGTVWRVAGMDSSDGLADAVLQICRASQVGAVIEALPLPATTSFDRDRLIQAALYGGEDFELVLCLSPDWAQALLELLGEQAQVIGQITEKPVVQLRLSDRTEILSLDRGFQHFTTH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: VM1AH_AGKCL
Sequence: MIQVLLVTLCLAAFPYQGSSIILESGNVNDYEVVYPRKVTPVPKGAVQPKYEDAMQYELKVNGEPVVLHLERNKGLFSKDYSETHYSPDGRKITTYPPVEDHCYYHGRIQNDADSIASISACNGLKGHFKLQGEMYLIEPLELSDSEAHAVFKYENVEKEDEAPKICGVTQNWESYEPIKKASQLNLNYQYQRYVELVTVVDHGMYTKYNGDSDKIRQWVHQMVNTMKESYRYMYIDISLAGVEIWSNKDLIDVQPAARHTLDSFGEWRERDLLHRISHDNAQLLTSTDFDGPTIGLAYVGTMCDPKLSTGVVEDHSKINFLVAVTMAHEMGHNLGMRHDTGSCSCGGYSCIMSPVISDDSPKYFSNCSYIQCWDFIMKENPQCILNKPLRTDTVSTPVSGDELLEA
What is the function of this protein?
This zinc hemorrhagic metalloproteinase has fibrino(geno)lytic activities.  It causes hemorrhage and has myonecrotic activity on both fiber types I and II.  The recombinant enzyme, without post-translational modifications, also has proteolytic activity, but does not show any hemorrhagic activity.
What are the official names of this protein?
Snake venom metalloproteinase ACLH, SVMP, ACL hemorrhagic toxin I, ACLH-I, ACLHT-I, Hemorrhagic metalloproteinase ACLH.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PG047_MONPV
Sequence: MPIFVNTVYCKNILALYTTKKFKTIIEAIGGNIIVNSTILKKLSPYFRTHLRQKYTKNKDPVTRVCLDLDIHSLTSIVIYSYTGKVYIDSHNVVNLLRASILTSVEFIIYTCINFILRDFRKEYCIECYMMGIEYGLSNLLCHTKDFITKHFLELEDDIIDNFDYLSMKLILESDELNVPDEDYVVDFVIKWYMRRRNRLGNLLLLIKNVIRSNYLSPRGIHNVKWILDCNIIFHCDKQPRKSYKYPFIEYPMNMDQIIDIFHMCTSTHVGEVVYLIGGWMNNEIHNNAIAVNYISNNWIPIPPMNSPRLYASGIPANNKLYVVGGLPNPTSVERWFHGDAAWVNMPSLLKPRCNPAVASINNVIYVMGGHSETDTTTEYLLPNHDQWQFGPSTYYPHYKSCALVFGRRLFLVGRNAEFYCESSNTWTLIDDPIYPRDNPELIIVDNKLLLIGGFYRGSYIDTIEVYNNRTYSWNIWDGMEW
What is the function of this protein?
Might have a role in the suppression of host immune response.
What are the official names of this protein?
Immune evasion protein OPG047, Kelch repeat protein.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG047 family.
Protein: YEIW_ECOLI
Sequence: MECRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKIFTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEMLTAP
What are the official names of this protein?
UPF0153 protein YeiW.
What is the protein family that this protein belongs to?
Belongs to the UPF0153 family.
Protein: SCXI_TITBA
Sequence: GKEGYPVDSRGCKVTCFFTGAGYCDKECKLKKASSGYCAWPACYCYGLPDSVPVYDNASNKCB
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  This toxin is only active against insects.
What are the official names of this protein?
Insect toxin TbIT-1, P-Ins-beta* NaTx4.3, TbIT-I.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.