PharMolix/UniProtQA huggingface dataset:
Protein: HIS8_VIBPA
Sequence: MEKLARKQVQELTPYLSARRIGGTGDVWLNANESPFNNEYKTDFARLNRYSECQPKALISAYAAYAGVKPEQTLTSRGADEGIELLVRAFCEPGQDAILYCPPTYGMYAISAETIGVERKTVPLTSDWQLDLAGIESNLDNVKLVFVCSPNNPTGNLVKREDIVSLLEMTKDRAIVVMDEAYIDFCPEASTVDLLAQYPNLAILRTLSKAFALAGLRCGFTLANEELINVLLKVIAPYPVPVPVAEIAVQALSEAGLARAKFQVLDLNANRAYLQVGLSMIPGLQVFEGWGNYLLVKFPDGDALFKAAWDTGIILRNSPIENCVRISVGNRDECEKTLGFIRNYYS
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: GLB2_PHAPT
Sequence: MTTLTNPQKAAIRSSWSKFMDNGVSNGQGFYMDLFKAHPETLTPFKSLFGGLTLAQLQDNPKMKAQSLVFCNGMSSFVDHLDDNMLVVLIQKMAKLHNNRGIRASDLRTAYDILIHYMEDHNHMVGGAKDAWEVFVGFICKTLGDYMKELS
What are the official names of this protein?
Hemoglobin-2, Hemoglobin II, Hb II, HbII.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O16A_CONBU
Sequence: MKLTCVMIVTVLFLTAWTFVTADDSTYGLKNLLPNGRHEMMNPEAPKLNKKDECSAPGAFCLIRPGLCCSEFCFFACF
What is the function of this protein?
Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.
What are the official names of this protein?
Delta-conotoxin BuVIA, Conotoxin Bu7, Delta-conotoxin-like BVIA, Delta-BVIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: WASC3_HUMAN
Sequence: MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTVEVSPLNVTSVTNGAHPEATSEQPQQNSTQDSGLQESEVSAENILTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGESEKTVEESSDSESSFSD
What is the function of this protein?
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
What are the official names of this protein?
WASH complex subunit 3, Coiled-coil domain-containing protein 53.
What is the protein family that this protein belongs to?
Belongs to the CCDC53 family.
What are the subcellular locations of this protein?
Early endosome.
Protein: PCKG_DROME
Sequence: MPELIEQSKIISGNVCGLPQLHKLRQDNCGLYSHIRGIPISYGNVDLLTTGVRAFVEEGIALCQPDQVHICDGSEQENKVLIKSLLEAGTIVPLPKYDNCWLARTNPADVARVESRTFICTERREETIPTPVEGVKGTLGNWISPSDMDAAVQQRFPGCMKGRTMYVVPFSMGPVGSPLSKIGIELTDSAYVVASMRIMTRMGAAVLRQLAKKEEFVRALHSVGAPANGQVEQPSWPCDPERTIILHKPAENLIVSYGSGYGGNSLLGKKCFALRIGSTIAKQEGWLAEHMLILGITDPKGEKKYITAAFPSACGKTNLAMLNPSLANYKVECVGDDIAWMKFDSQGVLRAINPENGFFGVAPGTSMETNPIAMNTVFKNTIFTNVASTSDGGVFWEGMESSLAPNVQITDWLGKPWTKDSGKPAAHPNSRFCTPAAQCPIIDEAWEDPAGVPISAMLFGGRRPAGVPLIYEARDWTHGVFIGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGDYVAHWLSMEKRGQVPKIFHVNWFRKSAEGKFMWPGYGENSRVLEWILRRVNGESCYVDSAIGHIPAEGALNLDGMKDKVDVKEIFSLPKEFWSQEVKDIRTYFESQVGADLPASIYQQLDELSSRVDNL
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], Phosphoenolpyruvate carboxykinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
Protein: KAD6_SULTO
Sequence: MIIIITGTPGSGKSTIVDLLSKKLGFEKLHVSSFLIQNKAFSEYDELRQSYVIDEEKAFQLIDSFIKDKNVVIETIYPSLISHADKVIVLRKDPRVLYTELKRRGWGELKIAENVMAEILGVISGEAKEYFGNICEINVTNKKPEEVVEQILSNNCDNVDWLNIEEIQDLLISLDKVISSYEDSISDE
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
What are the official names of this protein?
Putative adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
Protein: RPOZ_BRUAB
Sequence: MARVTVEDCVDKVENRFELVLLAGHRARQISQGAPITVDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEAAPAQIANAAEEIAEGIAEAGEEDVVTFDRMSEEELLAGIEGLVAPEKNDGF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MAP1_AQUAE
Sequence: MAIELYSQREIEKIRKASQIVAEVLHIVAENVKPGVSTWDLEMIARKETEKRGAKPAFLGYKPPFSDVRYPAALCISINDEVVHGLPKKEKVIKEGDVVSIDFGAIYDGYAGDSAITVIAGKGSPEAQKLLEATKEALYNAIEKALPGKKVGDITKAIHETAEKYGFKTILRYGGHGVGRKVHQEPFVPNNVKDIGKKNPRLRQGMVIAIEPMLSIGTEETVEDGDGWTVKTKDGSLAAHFEHTVAITKKGPVILTEL
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: PURQ_ANADE
Sequence: MRVGILTFPGSNCDHDCYHVVKHVMGAEAQYVWHKDRLPEQLDAVVVPGGFSYGDYLRCGALARFSPVIADLVTFAEKGGPVLGICNGFQILCEAGLLPGVLMRNASLKYICKDVTIRVEGQETPVTRGLAGQSLTMPIAHAEGNYFADPETLDRLEGEGRVVFRYVGGAPNGSARDIAGISGGPARNVVGLMPHPDRASESILGLEEGKRMFAALLG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_GLUDA
Sequence: MARVKRGVTTHARHKKVLEQSKGFRGRSSTNYRIALERLEKALRYAYRDRRNKKRDFRALWIQRINAAVREHGLTYSKFIFGLDKAGIEIDRKVLAAIAFDDAATFAEIVKKAQAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MUTL_LACAC
Sequence: MPKIHELSETLTNQIAAGEVIERPASVVKELVENSLDAGATRIRVDFVDAGLKQIVVQDNGTGIARDQVDLAFTRHATSKISNEHDLFKVATLGFRGEALASISAVSHVEILTATKGAIGVKATFSGGNKKGQEDAAAREGTQITVRDLFFNTPARLKYLRSPRTEIMKIVDIINRLALGYPSVSFTLSNTGKVLLRTPGNGNLKQTVANVYGRHIAEKMEEFEAKDNDFKISGLMSKPELTRSTRNFVSILLNGRYIRNFQLNTAIMDGYGAKLAARHYPIIVLAIQVDPLLVDVNVHPTKQEVRLSKEKELSRLITSTISNVFIKKTEQTSAFANLENKRETLVDQLQFNLNQNVVNTARKKTPEIHENNEKPEFLAKPKKPEEEKTDYVDLNIPREDDKYIITKTWDKNVLLQQDLRPFSNTLCDSEVISSGDETLANNLPQLSYIGQIDTYIIAENNSDLFLIDQVAARRRLQFEKIYEMLLSKKIVQQGLLTPIVLEFGNLDFIQIKDKIDQIKQIGIYLEDFGQNSFIVRSYPTWIHNDVEETIRQILDGYLNLDKGKSENLFKRVAAMQAKRDISGKINLAAAEASQILIDLRKTEDPYHDADGRLVLVRMSENELKKMFKRDK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DCTR_ECO57
Sequence: MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVIIDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALINGSYCSVPEANVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNLKRINELVRHQHIDYLV
What is the function of this protein?
May act as a transcriptional regulator of dctA (By similarity).  Could be involved in the regulation of the genes coding for the type III secretion system in enterohaemorragic strains.
What are the official names of this protein?
HTH-type transcriptional regulator DctR.
Protein: TRP3_PSEAM
Sequence: MILLLVLALGLAGASPLGEYKECPPHSRPWQVNLHDGKMSCSGALIDRWWIVTSFDCALTAHRTIATLGDHDLTVEEGTEQHIPVAEVIVHSPYRSPLHSLTMVRLAQPAQFNQHVQPVPLASRCPQPGEICSVSGWGSTRPNHFEPQQRLKCITVPVVDDQTCVNTFPQYLYWSQHMVCAGRADTDNCMSNRGSVMVCGGQLQGVQWFNHGCKDPAHPSVYSKMCLYNDWIHQVMARHPPFETTTVSTTTRGRKD
What are the official names of this protein?
Trypsinogen-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: ALFL4_ORYSI
Sequence: MDGGYGSVTIVHDARSPEDVFQDFCGRRSGIVKALTIEVEKFYKQCDPEKENLCLYGLPNGTWAVTLPADEVPPELPEPALGHNFARDGMQEKDWLSLIAVHSDSWLLSVAFYFGARFGFDKKARERLFMMTSSLPTVFEVVSGGVNTQSKTANGSSKNKSGSKPPKRPNSDSKPQKQVQAKYEEENGGRGNGGDEDQAETICGACGEAYANGEFWICCDICETWFHGKCVRITPAKAEHIKHYKCPGCSNKRTRE
What is the function of this protein?
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
What are the official names of this protein?
PHD finger protein ALFIN-LIKE 4.
What is the protein family that this protein belongs to?
Belongs to the Alfin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACH10_ARATH
Sequence: MTENSEKIDRLNDLTTFISTKTGVKGLVDAEITEVPSMFHVPSSILSNNRPSDISGLNLTVPIIDLGDRNTSSRNVVISKIKDAAENWGFFQVINHDVPLTVLEEIKESVRRFHEQDPVVKNQYLPTDNNKRFVYNNDFDLYHSSPLNWRDSFTCYIAPDPPNPEEIPLACRSAVIEYTKHVMELGAVLFQLLSEALGLDSETLKRIDCLKGLFMLCHYYPPCPQPDLTLGISKHTDNSFLTLLLQDQIGGLQVLHEDYWVDVPPVPGALVVNIGDFMQLITNDKFLSVEHRVRPNKDRPRISVACFFSSSLSPNSTVYGPIKDLLSDENPAKYKDITIPEYTAGFLASIFDEKSYLTNYMI
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase homolog 10.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RL6_ECO55
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: APT_DESHY
Sequence: MKALDFDKYIRVIDDFPKPGISFKDITTLLKDGEAYRAAVDAIVERVRESQPDLIVGPEARGFLLGAPVAYALGIGFVPVRKPGKLPGKTVSETYELEYGSDTLEVHADAIQPGQRIAIVDDLLATGGTTSATARLIEKTGAQVAGMSFLIELGFLEGRKRLEGYEVFSLIKY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2962_YERPN
Sequence: MYDNLKSLGITQPEDVDRYSLRQEANNDILKIYFRKDKGEFFAKSVKFKYPRQRKTVVSDNASHGYKEINEINPNLRYVIDELDQLCKRDQIEVDLKRKILDDLRHLESVVTNKIAEIEADLEKLTNGR
What are the official names of this protein?
UPF0325 protein YPN_2962.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: EVS_STIAD
Sequence: MPSTGSTPILAHDVKSPHRGSLALDGGKTGYRVTVHREDRYEIIIGRGTLARLGELLRPVMAANEADSAVIITDNHVGPLYAELVTKRISATGAPVQCIVIPAGEPSKSIAQAHRLWDELRSRSVRRRTFLVALGGGVLCDLVGFVATTYLRGIPYVNVATSLMGQVDGAIGGKVGVDHSTGKNLIGGFYHPDLVVIDPSCLATLPLAEVINGLAEAVKVALIGTPGLFEQLERLPMSTAWPLDQAAPERLIEGLGPIIPAAIGKKLELLAPDPFEQDLRRLLNLGHSVGHGLEAATHFVRYRHGEAVAIGTATVTAISTGLGLTSVDTLRRILRLLQKLRLPVTVPDDLREVVWQHLETARLVRNGRLLLVMPTAIDHSVIIDDITRGQYDAACQLVAQEAPACG
What is the function of this protein?
Catalyzes the conversion of sedoheptulose 7-phosphate to 2-epi-valiolone, which may serve as an alternative precursor for aminocyclitol biosynthesis.
What are the official names of this protein?
2-epi-valiolone synthase, EVS, Sedoheptulose 7-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. EVS family.
Protein: ABNC_ASPNC
Sequence: MLSFVLLLCVALVNAYSDPGACSGTCWAHDPNVIRRVSDGTYFRFSTGGGVHISSASAITGPWTDLGYALPNGSIVTVGNASNLWAPDVHYVDGTYYMYYASSTLGSRDSTIGVATSTTLEADSWTDHGEIGVTSSSSTPYNAIDPNWITIGSTPYLQFGSYWQGLYQVEMTDSLSASSSTPTNLAYNASGNHAIEASYLYEYGGYYYLTFSSGKAQGYTTSLPAQGDEYRIVVCRSKTGTGNFVDKDGVSCLNSGGTTVLASHDYVYGPGGQGIINTTSHGIVVYYHYANKNIGLAVDDYQFGWNTLTWTDGWPVVA
What is the function of this protein?
Endo-1,5-alpha-L-arabinanase involved in degradation of pectin.  Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).
What are the official names of this protein?
Probable arabinan endo-1,5-alpha-L-arabinosidase C, Endo-1,5-alpha-L-arabinanase C, ABN C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCKN_DASVI
Sequence: DYMGWMDF
What is the function of this protein?
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut.  Its function in the brain is not clear.  Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
What are the official names of this protein?
Cholecystokinin, CCK.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBS1_NICSY
Sequence: MASSVLSSAAVATRSNVAQANMVAPFTGLKSAASFPVSRKQNLDITSIASNGGRVQCMQVWPPINKKKYETLSYLPDLSQEQLLSEVEYLLKNGWVPCLEFETEHGFVYRENNKSPGYYDGRYWTMWKLPMFGCTDATQVLAEVEEAKKAYPQAWIRIIGFDNVRQVQCISFIAYKPEGY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 1, RuBisCO small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UVRC_ACIBY
Sequence: MNQNARPHIEKILANLTQLPGVYKMLGKEGELLYVGKAKNLKNRVSSYFVKTIEHPKTQALVARIYDIETLVTRSETEALLLEQNLIKQHRPPYNIMLRDDKSYVYIFVSADKPYPRIASGRGKGKHQIGKFFGPYPSAYSARDTLLVLQKLFNVRQCENSYFSQRKRPCLQYQIKRCSAPCVGLVSPEDYKEDVNNSIRFLQGDTKELNQELIAKMEQAAADLEFEKAVFYRDRLSLLREVQAQQAVFKVKGEADILAIAYQAGVTCVQIMHVRNGRMLGGKSYFPDMLGDDLGQMLSDFMANFYFQVADEVPSELIVNTALPDRKELEEALAQQFGKKVQIKSSVRETRAEWLELAEMNVQHAIKGQLSNHLELNERFHQLEQVVGRPIDRIECFDISHTMGEAPIASCVVFDQGGARKRDYRQFAIQDITAGDDYAAMRQALTRRYKKAMLPDLLLIDGGKGQLHMAMEVMQELGLEAFMVGVSKGEGRKPGLETLHFTDGTKIQLPEDSKALHLIQQVRDEAHRFAITKHRAKRDKRRSTSVLEAIPGLGPKRRRDLLTHFGGIQGVLKASEKELTVVPGLGEVMARTIYKILHE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOA_DICTD
Sequence: MNLIWGFLILILVLIFLGVFFSFVPLGLWISALAAGVSIRITDLIGMRLRRVPPGVIINSLIKAHKAGLSEVTLDKLEAHYLAGGNVDKVVNALIAAQRAGIPLTFEKAAAIDLAGRDVLEAVQMSVNPKVIETPVVAAVAKDGIELKAKARVTVRANIERLVGGAGEATIIARVGEGIVTTIGSAESYKEVLENPDSISKTVLAKGLDAGTAFEIVSIDIADVDVGNNVGARLKMDQAEADMRIAQAQAESRRALAIAREQEMKALTQEMRARLIEAEKEVPLAIAEALRSGKIGVLDYYTLKNIIADTAMREAISKLGQKEEEGRKD
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein.
Protein: RL19_CLOBM
Sequence: MLEVIKAIEAEQVRNDLPEFHVGDTVKVHQKIKEGTRERVQIFEGTVLKRQNGGARETFTVRRVAYNVAVEKTFPVNSPLIEKIQVVRKGKVRRAKLYYLRDRVGKAAKVKERI
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SYE_PSEPG
Sequence: MTTVRTRIAPSPTGDPHVGTAYIALFNYCFAKQHGGEFILRIEDTDQLRSTRESEQQIFDALRWLGIEWNEGPDVGGPHGPYRQSERGDIYAKYAKELVDAGHAFYCFCTAEELEQMRAEQQARGETPRYDGRALLLSAEEVQRRLDAGEPHVIRMKVPSEGICVVPDMLRGDVEIPWDRMDMQVLMKNDGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLIKLYEYFGWEQPKLCYMPLLRNPDKSKLSKRKNPTSVTFYERMGFMPEAMLNYLGRMGWSMPDEREKFSLAEMVEHFDLSRISLGGPIFDIEKLSWLNGQWLRELPVEEFATRLQKWAFNSDYMMKIAPHVQGRVETFSQVAPLGGFFFEGALKLDAKLFESKKLSADQVRQVIQLILWKLESLRQWEKERITGCIQAVVEALELKLRDAMPLMFAAITGQASSVSVLDAMEILGPDLTRYRLRQALDLLGGVSKKENKEWEKLLASIA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_DESA1
Sequence: MGKRIIPQRRGKASPVFKTPDHIHVAPARYPLLDPSKTYKAVVEDLVHDPGRWVPLAQVKLETGLVFYVPAVEGMYAGQIIEIGPGAKPVNGNILPVGMIPEGMQVVNIEKRPGDGGKFVRASGTYAVIVGRAGGKTQVQLPSGRVIEVPNESRAMIGVIAGGGRLEKPLLKAGAAYYKWSAKSRVWPKVRGVAMNAAFHPHGGGSHQHVGRPSTVARNTPPGRKVGHIAARRTGRRKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ATPD_STRTD
Sequence: MDKKTQALVEQYARSLVEVAFEQDAVSTIQEEVRQILTVFAETNLKTFLSQVNVTSEAKKESLSFFQESCSVYMNNFLEVISLNDRANILYDVLKLVLELFDQEDNTYDVTVTSASPLSEEQKTRLLTIVSQKFEIKTRRLVEKIDEELIGGFVIKAKNKFVDTSIRSQLQAFKMNLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TSH2_PIG
Sequence: MPRRKQQAPKRAAGYAQEEQLKEEEEIKEEEEEEEDSGSVAQLQGSNDPGTDEELETGAEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCSRDASDKKASVHPKLPTEAHSCMDKMTAVYANILSDSYWSGLGLGFKLSSSERRHCDTRNGSSKTDFDWHQDALSKSLQQNLPPRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADPFPAPKNASLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSDAPSSDSLAPKPSSNSASDCTASTTELKRESKKEKPEELRTDEKVLKSEDYEDPLQKPLDPAMKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPSLPMGSQVLQIRPNLANKLRPIAPKWKVMPLVSVPTSLAPYTQVKKEPEDKEEVAKECGQESPHEEASSFSHSEGDSFPKSEPPAESKKAEPCPLREEDKRMKDGGEKEKAQPVEPVSSLSNGCALAAHAPAPPCVNPLSALQSVLNNHLGKATEPLRSPSCSSPSSSTMAMFHKSSLGVMDKPVLSPASTRPASVSRRYLFENNDQPIDLTKSKSKKAESSQAQSCTSPPQKHALSDIADMVKVLPKATTPKPAASSRVPPVKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRMAVEQQSQVEQEISRVSSAQRSPETIAGEEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHAQFVTDVDEE
What is the function of this protein?
Probable transcriptional regulator involved in developmental processes.  May act as a transcriptional repressor (Potential).
What are the official names of this protein?
Teashirt homolog 2.
What is the protein family that this protein belongs to?
Belongs to the teashirt C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROF2_PONAB
Sequence: MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-2, Profilin II.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL28_CAMJ8
Sequence: MARVCQITGKGPMVGNNVSHANNKTKRRFLPNLRTVRVTLEDGTTRKMRIAASTLRTLKKQNSK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RNH3_STAEQ
Sequence: MGNVVYKLTSKEIQSLMAQTTFETTKLPQGMKARTRYQNTVINIYSSGKVMFQGKNAEQVASQLLPDKQSTTGKHTSSNTTSIQYNHFHCIGSDEAGSGDYFGPLTVCAAYVSQSHIKILKELGVDDSKKLNDTKIVDLAEQLITFIPHSLLTLDNVKYNERQSLGWSQVKMKAVLHNEAIKNVIQKIEQDQLDYIVIDQFAKREVYQHYALSALPFPDKTKFETKGESKSLAIATASIISRYAFVKHMDHISKKLHMEIPKGASNKVDLIAAKVIQKYDIQQLDTISKKHFKNRDKAIHLINQKYNK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.