PharMolix/UniProtQA huggingface dataset:
Protein: GYRA_AMICL
Sequence: MEEKKGEPLFGKVVPLPLVEEIKHSYLDYAMSVIVGRALPDARDGLKPVQRRILYAMMELGLRHNTAYKKSARVVGETMGKYHPHGDSAIYDTMVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLYEIGELMLADIDQDTVDWGPNFDESLQEPLCLPAMLPNLLINGSSGIAVGMATNIPPHNLVEVVDALCYLIDTEPEQVDIGEILFRMPGPDFPTGGLILGRDGIIDAYRTGRGKITMRGRTHIEEGKRGKTFIVITEIPYMVNKTNLIETIAKNVQDKTIDGVMDLRDESDREGLRIVIEVNRDTDPNLVLRQLYRRTQLQSTFGVINLALIDGYPKELSIEEMLNIFLNHRRSVVRRRTQFRLEKAEARAHIVEGLVKALDIIDEVIALIRGSATTEEAKEGLISKLDFSEAQAQAILEMRLQRLTGLEREKLEAELAQLLSDIERYQTILGNPKVLDSVIKEELLEVKRRFGNERKTEIIDAVEDVSIEDLIPESDIVVVLSRDGYLRRKDLQEYTLQGRGGKGRKGTALQEEDEVALVAVTSTHRDIYLFTSKGRVLALKGYVIPESKTGRGKLINRFVALEEGERVVTMHGRAVDGAKYAFFITLRGTAKRLDLSELENLTRAGRRVMGLDEGDEISQIVLTSGDDHLLIVTAQGQALRTHESEFRPMGRTARGVRGIRLRKNDYVIGCDVVANGRWPLLLSENGFGKRTKYDEFSLRHRGGSGVIVMNLSDRTGLIVGCWSVAEGDEIVAITSRGRMIRLAVSESPVLGRTAMGSIMMRLDEGDTVATASVVSTEDGEDD
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_LATSS
Sequence: MPKFKTHRASAKRFKRTGNGGLKRSHAYTSHRFHGKTKKQRRQLRKSGMVSNSDMRRIRQMLSGLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: NU2M_CROSG
Sequence: MNPMIFIILLTTIMLGTFIVTTSSHWFMTWLGFEMNMMAIVPVLMKKYSPRSMEAATKYFLTQATASMILMLAIIINLMYSGQWTITNMENYTASMLITIALTMKLGLAPFHFWVPEVTQGVSLPSGLILLTWQKIAPLSLLYQTYSSVNMNILLLMSLLSIMIGGWGGLNQTQLRKIMAYSSIAHMGWMMAIMVYNPNLSLLNLLIYIFMTSSMFMLLIFSSSVSTLSLSLTWNKAPIITIMSLTTLLSLGGLPPLTGFLPKWMIIQELTKNNSVILPTLMAILALLNLFFYMRLTYSTALTMFPTMNNTKFMWQFQNTNILSMMLPLITISTLALPLTPMLILLN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RCEH_CERSP
Sequence: MVGVTAFGNFDLASLAIYSFWIFLAGLIYYLQTENMREGYPLENEDGTPAANQGPFPLPKPKTFILPHGRGTLTVPGPESEDRPIALARTAVSEGFPHAPTGDPMKDGVGPASWVARRDLPELDGHGHNKIKPMKAAAGFHVSAGKNPIGLPVRGCDLEIAGKVVDIWVDIPEQMARFLEVELKDGSTRLLPMQMVKVQSNRVHVNALSSDLFAGIPTIKSPTEVTLLEEDKICGYVAGGLMYAAPKRKSVVAAMLAEYA
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein H chain, Photosynthetic reaction center H subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PuhA family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Single-pass membrane protein.
Protein: RH3B_MAIZE
Sequence: MASLTLPALALALSNPGAVRLRAAAFRCWALRRRGWAAAGALASPNSVLSEHAFKRLQLGSDDEDGEGPYGSDADEGFEAGEGDNEELAIARLGLPDELVATLEKRGITHLFPIQRAVLIPALEGRDLIARAKTGTGKTLAFGIPMIKQLIEQDDGRITRRGRTPRVLVLAPTRELAKQVEKEIKESAPKLGTVCVYGGVSYNVQQNALSRGVDVVVGTPGRIIDLINGGSLQLGEVQYLVLDEADQMLAVGFEEDVETILQQLPAGRQSMLFSATMPSWVKKLSRRYLNNPLTIDLVGDQDEKLAEGIKLYAIPLTTTSKRTVLSDLITVYAKGGKTIVFTRTKKDADEVSLALTNSIASEALHGDISQHQRERTLNGFRQGKFTVLVATDVAARGLDIPNVDLIIHYELPNDPETFVHRSGRTGRAGKAGTAILMFTSSQKRTVKSLERDVGCNFEFISPPSIEEVLESSAEHVIATLRGVHPESTKYFLGAAEKLTEELGPHALASALAHLSGFSQPPSSRSLISHEQGWVTLQLTREQGFGRGFFSPRSVTGFLSDVCSAAADEVGKIYLTADENVQGAVFDLPEEIAKDLLTMELPPGNTLTKISKLPALQDDGPATDSYGRFSNDRGSRNNRRSRGGGASRGRGGWDTDGEDRFRRGGRSLRSDNDSWSDDDWSGGGRKSNRSSSFGSRSSSYSSRGSPSFGGRSSSFGGRESNRSFSGACFNCGESGHRATDCPNK
What is the function of this protein?
Nuclear genome-encoded factor involved in ribosome biogenesis in chloroplasts.  Binds specific group II introns in chloroplasts and facilitates their splicing.  Is required for rRNA maturation in plastids and may contribute to the assembly of the large (50S) ribosomal subunit.  Required for normal development of chloroplasts.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 3B, chloroplastic, ZmRH3B.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: YNZD_SCHPO
Sequence: MRFISTVTKRRPFQAPNDLVHPLSNILGSLVTYDSRLHLPQPKDRQCSTLVPLYRRLLKATRRFWDPMASQILISHFQAYARKARKSNPNPHKRRIKRFRNLLKTFACRIERANDGDHQAIWQTLRYAYSQTGPLRHRRLHYLQDNKIRPSKIPKSLPSNSPVRLPYISSLLSAVFEINMENAKIRHLPSVIFDGLIEKNKDRPYHINLSCKRAYDELLPRIAVPLLPHEYHHLHSLLLDVTLRNPQISRPPFAPLNPRKGFCRILQRSLITFLSAVCYLPYNPHPTSKPVVSWDSLSDIQLRLNVGKVLKKSVKKR
What are the official names of this protein?
Uncharacterized protein C17G9.13c.
Protein: ACO12_MOUSE
Sequence: MESMVAPGEVLMSQAIQPAHADSRGELSAGQLLKWMDTTACLAAEKHAGISCVTASMDDILFEDTARIGQIITIRAKVTRAFSTSMEISIKVIVQDKFTGIQKLLCVAFSTFVAKPVGKEKVHLKPVLLQTEQEQVEHNLASERRKVRLQHENTFNNIMKESSRFSDSICNEEEGTATTMGTSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCHGHPFLKSVDMFKFRGPSTVGDRLVFSAIVNNTFQNSVEVGVRVEAFDCQEWAEGQGRHINSAFLIYNAVDDQEKLITFPRIQPISKDDFRRYQGAIARRRIRLGRKYVISHKKEVPLSAQWDISKKGSLSNTNVEALKNLASKSGWEITTTLEKIKIYTLEEQDAISVKVEKLVGSPAHIAYHLLSDLTKRPLWDPHYISCEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSRRKPLKDNNTYTVALRSVVLPSVPSSPQYIRSEVICAGFLIQAVDSNSCTVTYLNQMSDSILPYFAGNIGGWSKSIEEAAASCIKFIENATPDGLKSVL
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.  Preferentially hydrolyzes acetyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A thioesterase, Acyl-CoA thioester hydrolase 12, Acyl-coenzyme A thioesterase 12, Acyl-CoA thioesterase 12, Cytoplasmic acetyl-CoA hydrolase 1, CACH-1, mCACH-1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PLSX_ACIAC
Sequence: MITLAVDCMGGDHGPRVTLAACRQFLEHHPQARLLLVGQPESLGGFAHERAQIVPASEVVSMDDPVEVALRRKKDSSMRVAVQQVKDGAAQVAVSAGNTGALMAIARYLLKTLDGIDRPAIATQMPNARGGATTVLDLGANVDCSAEHLLQFAVMGAALVSALHEGTEEPAVGLLNIGEEVIKGNEVIKRTGELLRSAAESGDLNFYGNVEGNDIFKGTVDIVVCDGFVGNVALKASEGVASMIVGALKQEFKRSIFTKIAAVVAYPVLSALMRRMDHRRYNGAALLGLRGLVFKSHGSADILAFEQALIRAYDTARNNLLDRVRSRVAHAAPLLGPAAAQPSP
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MEP1_UNCRE
Sequence: MRLSVSLLALAFGSLVAAAPNTKPRTCGSKPSMEFLAKSAEFAAKEASGELLNSLATIEVETYFHVVASGRTPSQGYLSDAMLANQLRVMNSDYGPHGIQFNLVRTTRTVNANWARDGDELGMKRALRQGGYNALNVYFLGDLGSLLGYCYFPTNASPGSTAFIRDGCVVVGQSVPGGNISNYNLGKTATHEVGHWFGGCFGSGDGVSDTPPQRSSTQGCPSSRDSCPGGGVDPIHNYMDYSYDVCMNQFTSGQRTRIYNMWNQYRARG
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Extracellular metalloprotease UREG_07765.
What is the protein family that this protein belongs to?
Belongs to the peptidase M43B family.
What are the subcellular locations of this protein?
Secreted.
Protein: LCA5_MOUSE
Sequence: MGERARSPDIEQGKKGGKHPYSHYSSDLGSSPQSSGPSSPVNTTPCASTREKNPKRHLSDNQVHHPTVRKVSPKAVPSKKGIRVGFRSQSLNREPLRKDPDIVTKRVLSARLLKINELQNEVSELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEISQLIHRHNNEITALKERLRKSQEKERATEKRVKETEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKVLQKELQRLHHKLKEKEKELDIKNIYANRLPKSSPKKEKEIERKHVSCQSDFTDQCTKGVQTAEDFELEDFPFTAQTVLCYENRWDEPEYLSSYLEYQDLNKHGSEMLSSVLGQEGKYDEDEDPCSAKQEARKPESEWAREELDKVKGKSALLGRAEKLALEAGRFPTENYQAQSVDKFEDEAERLKTEMLLAKLNEINKELQDPQNLGRAPLPLLPNFESKLHSPDRSTRPYSFPESLDRSFNGQHLQDLSFLTPRGEGGSPGPIRSPGQIRSPAPLDEFSFGSYVPSFGKTLGKSNPPSQKSSLLDFQSNSSESPSKDSLDLMSRKEKKATLMEQLFGPSASNTSVSSKSTDPHFPAASRGDMDPLHFLSGDRNSRVREPGDEEEDLFLREGRSFNPNRHRLKHASNKPTVTAVDSVDEDIEEVTLR
What is the function of this protein?
Involved in intraflagellar protein (IFT) transport in photoreceptor cilia.
What are the official names of this protein?
Lebercilin, Leber congenital amaurosis 5 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the LCA5 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Note=Localized to the region between the outer and inner photoreceptor segments, corresponding to the photoreceptor connecting cilium (PubMed:21606596, PubMed:17546029). Colocalizes with IFT complex A and B proteins in the connecting cilium of photoreceptors (PubMed:21606596).
Protein: NCB5R_COCIM
Sequence: MSSWTSKENINGVYIPSALLIFGTTIIKKEWIAYATALAVVLSAWKLFSNKPRKVLNPTEFQNFVLKDKTIVSHNVCIYRFALPRPTDILGLPIGQHISLAATIPGQSKEIVRSYTPISSDDDAGYFDLLVKSYPQGNISKHLTTLRIGDKMKVRGPKGAMVYTPNMVRHIGMIAGGTGITPMLQVIKAIIKGRPRNGGNDTTQIDLIFANVNPDDILLKEELDQLAKEDDAFRIYYVLNNPPEKWNGGVGFVTPDMIKAKLPAPAGDIKVLICGPPPMVSAMKKATESLGYKKANLVSKLEDQVFCF
What is the function of this protein?
NADH-dependent reductase for DPH3 and cytochrome b5.  Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.  By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex.  The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.
What are the official names of this protein?
NADH-cytochrome b5 reductase 1, Microsomal cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RLMH_SHEON
Sequence: MKLQLIAVGTRMPDWVTRGFEEYQRRFPRDMALELIEIPAGKRGKNADIVRILQKEGEQMLAAIPKGNHIVTLDLPGKNWTTPELASAMNKWQLDGRDVSLLVGGPEGLAPACKEAAHQSWCLSALTLPHPLVRIVVAESLYRAWSVNTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNFN_BOVIN
Sequence: MSYPVTSQPQSASTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCTPYLPGGLHSLRTGMRERYRIQGSIGKDWAALTFCLPCALCQMARELKIRE
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Cornifelin.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: PHOU_SHIFL
Sequence: MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYREDKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVKGQDFRHVGGDELDKLLAGKDSDK
What is the function of this protein?
Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis.  Encoded together with proteins of the phosphate-specific transport (Pst) system in the polycistronic pstSCAB-phoU operon.  PhoU is essential for the repression of the Pho regulon at high phosphate conditions.  In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR-PhoB transitory complex (By similarity).
What are the official names of this protein?
Phosphate-specific transport system accessory protein PhoU, Pst system accessory protein PhoU.
What is the protein family that this protein belongs to?
Belongs to the PhoU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MK01_BOVIN
Sequence: MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPVAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
What is the function of this protein?
Acts as a transcriptional repressor.  Binds to a [GC]AAA[GC] consensus sequence.  Repress the expression of interferon gamma-induced genes.  Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1.  Transcriptional activity is independent of kinase activity.
What are the official names of this protein?
Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Membrane, caveola. Cell junction, focal adhesion. Note=PEA15- binding and phosphorylated DAPK1 promote its cytoplasmic retention. Phosphorylation at Ser-246 and Ser-248 as well as autophosphorylation at Thr-190 promote nuclear localization. Associated with the spindle during prometaphase and metaphase.
Protein: FSX1_NATA2
Sequence: MRAVSDFLKNKWVAVPAVALLILSLGFLAQNYITGSFVSGDQIEYTSNSEFFDGEVFVINYIGDRTTDKIHAEIPASELASAADGEVTKELTIDITSQETYARYSTTSTSLSRIYAFKAINSEVFTDTSSSEVESRKQSWAEQNCYDIDGDSEIEQGDDYTQRFWVDGAIADYYNAQVYCVRENGYYGNIAELSSPDKEFEAEVEVKADGETPQSTTLSNSDLGQGRCDNIGEYVRACWTGLNPTGEGVPEPYNVYAIHSNTFSPEWRVISAERYSSYNSYVENNLYSQIEAWKEGSLSQEEVVSTANDQAAQAAQRVSSGSFTDYQVEDSSYENGQIRLNPSYDIAWPEFTFYVDGADYISVEKPVGEPRIVNVEGDEFGEKQSGTVTAEVENTASYEGSFSARVSKCSDSFGYDSLQETKTVGPGETVSFDFRVSFTSDSFDQKTVSGSCEIVVSDTGDSSNSDTAVVDVEATQSNECTPNEEFVRTINSTHSRILECSSDGLTTTEVDVCGDGEEAAFRDSSWTCVSDGTLPGGGDGSGGSGGGGDTDDCVVFAVGDLEIEDPFCADGPLEMLSKMFHLVAGTAVAFFTGSLGYRAGRWVDGEYQIKGGFDPLKSRSVSRAKRGRFLIGLIAELVSFLLGFYVILLVPIWAQLMVILGYVLFKYYTPF
What is the function of this protein?
Exhibits fusogenic activity (PubMed:35794124).  Mediates cell-cell fusion in mammalian cells (bilateral fusion) (PubMed:35794124).
What are the official names of this protein?
Fusexin 1, NaFsx1.
What is the protein family that this protein belongs to?
Belongs to the HAP2/GCS1 family. Fusexin 1 subfamily.
Protein: RBL_CALDI
Sequence: DILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVLGEKDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDXFLFCAEALYKAQCETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMTFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVXHMPALTEIFGDDAVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAAEGNVIIREXSKWSPELAAACEVWKEIKFEFKAVDTLDPEK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KDSA_SHIB3
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_NITEU
Sequence: MARNVVVIGTQWGDEGKGKIVDWLTDRATGVVRFQGGHNAGHTLVVGGEKTVLHLIPSGILRENVTCYIGNGVVLSPGALLEEVDMLEQAGVDVSGRLRISETCPLILPYHIAVDGARELAKGMEKIGTTGRGIGPAYEDKVARRAIRLQDLFRPERLACKLKEVLDYHNFLLKNYYHAATVDYHQVLDDCQIKAERIRPMVADVPKLLFEASQADNNLLFEGAQGALLDIDHGTYPFVTSSNCIAGAASVGSGVGPQMLNYVLGITKAYTTRVGSGPFPTELSDATGEHLAQRGNEFGSTTGRPRRCGWFDAVAARRSIQINGVSGLCITKLDVLDGLETLRIGVGYKSKQSGEMYDALPFGADDLAAAEPVYEELPGWQERTAGIRNFDQLPQAAQNYLKRMEEVCQTPISMISTGPDRTETIVFHHPFG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXXF_BACSU
Sequence: MQQDPSISSKQKSTAVIKMVISMVIFGSIGFFSEHTNLPSFELVFVRCLCATLFLGFCWLASGQYKTEKWSKRDVLQTLACGFFLVFNWVFLFKSFEETSVTIAISVYHLAPVLVLLLGSFFYREKLNVISVSSIIICFLGTALISGINGSTSLTQLMGSGIIWAVLAALFYAFTTLLGKGIHNLSPYTTTFLQTGLGVIILIPFIHFGAFADLSQGNWIMVVSTGIIHTGIVYLLFFDSLRFLSTKFISIIVFLDPAVAIVLDTVFTGFRPDLYQTLGIVMIFAGMALTLVRRQGKANVTAEGTDIEQIQ
What are the official names of this protein?
Uncharacterized transporter YxxF.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NART_STAA1
Sequence: MYKTKGGFQLTLQTLSLVVGFMAWSIIAPLMPFIKQDVNVTEGQISIILAIPVILGSVLRVPFGYLTNIVGAKWVFFTSFIVLLFPIFFLSQAQTPGMLMASGFFLGVGGAIFSVGVTSVPKYFPKEKVGLANGIYGMGNIGTAVSSFLAPPIAGIIGWQTTVRSYLIIIALFALIMFIFGDTQERKIKVPLMAQMKTLSKNYKLYYLSYWYFITFGAFVAFGIFLPNYLVNHFGIDKVDAGIRSGVFIALATFLRPIGGILGDKFNAVKVLMIDFVIMIIGAVILGISDHIALFTVGCLTISICAGIGNGLIFKLVPSYFSNEAGSANGIVSMMGGLGGFFPPLVITYVANLTGSSHLAFIFLAVFGCIALFTMRHLYQKEYGSLKHS
What is the function of this protein?
Probably required for nitrate uptake under anoxic conditions.  Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate (By similarity).
What are the official names of this protein?
Probable nitrate transporter NarT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUEF_CHLPD
Sequence: MKKEILEVFDNTFPGRDYTIEIVNPEFTSVCPITALPDFGTIIIRYIPDKSCVELKSLKYYFLEFRNAGIFYENITNTILDDLTSVLQPREMTVITQWKARGGITETVSVTWPQKQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CREB_ASPFU
Sequence: MGSFLRSFRHNGGSTAPSVGAVPAKKEPQPPPMTPLEKRLLDMGPIREDGSDKFYGMENYGNTCYCNSILQCLYYSVPFREAVINYPTRTPIESLEAALAKSLRYPNPNAQLEAEAQAEKQKAANAQRPGMPPNPQQKPEDKDSPEYKKKMALQTLPLLETQNNASSYGMSESLFTSLKDIFESVVGSQSRIGIIRPQQFLEVLRRDHEMFRTAMHQDAHEFLNLLLNEVVANVEAEASKQPPIEKSLPAPETADSVDQSSSTGSKTPNTTRWVHELFEGLLTSETQCLTCEKVSQRDEVFLDLSVDLEQHSSVTSCLRKFSAEEMLCERNKFHCDNCGGLQEAEKRMKIKRLPRILALHLKRFKYTEDLQRLQKLFHRVVYPYHLRLFNTTDDAEDPDRLYELYAVVVHIGGGPYHGHYVAIIKTEDRGWLLFDDEMVEPVDKNYVKNFFGDKPGLACAYVLFYQETTLEAVLKEQEQENMDSNLAATDANDTILKQNGFPQSPLAHVHSASQIPSHEDNLRPNGLRRAPTAPQLSTHHEHGDPESAPFSPLSPLSPLSPLSPLSQTPPVPPVPERVTTVATPPKNDALAKKERAREEKERKAAEKEREKAEKLRRKEQEARMKENQRREEAELKAALEMSKASKAEEDRRLSHENGKEKQGGSLSRLKRGSKSLSHRLGKDKETRSVSSDLPPVPIPEHSTLSQTGPTSEQQQQQQQQQSPPNHDQPPNSPQLGKPTIREDEQVNHKDSKHERTGHGKWRSFSLRKKSFSILS
What is the function of this protein?
Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Deubiquitinates the creA catabolic repressor and the quinate permease qutD.  Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase creB, Carbon catabolite repression protein B, Deubiquitinating enzyme creB, Ubiquitin thioesterase creB, Ubiquitin-hydrolyzing enzyme creB, Ubiquitin-specific-processing protease creB.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: RL31B_YERPA
Sequence: MKPNIHPPYRTVVFHDTSADAYFTVGSTIATERTIERDGQTYPYVTLDISSASHPYYTGKQKEFAKEGSTARFHQRFGSFLTKKTN
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: AADB2_KLEPN
Sequence: MDTTQVTLIHQILAAADERNLPLWIGGGWAIDARLGRVTRKHDDIDLTFPGERRGELEAMVEMLGGRVTEELDYGFLAEIGDELLDCEPAWWADEAYEIAEAPQGSCPEAAEGVIAGRPVRCNSWEAIIWDYFYYADEVPPVDWPTKHIESYRLACTSLGAEKVEVLRAAFRSRYAA
What is the function of this protein?
Mediates bacterial resistance to kanamycin, gentamicin, dibekacin, sisomicin, neomycin and tobramycin by adenylating the 2''-hydroxyl group of these antibiotics.
What are the official names of this protein?
2''-aminoglycoside nucleotidyltransferase, AAD(2''), Gentamicin 2''-nucleotidyltransferase, Gentamicin resistance protein.