PharMolix/UniProtQA huggingface dataset:
Protein: NADA_THENN
Sequence: MIDKILKLKKEKGYVILAHNYQIPELQDIADFVGDSLQLARKAMDLEEKKILFLGVDFMAELVKILNPEKKVIVPDRSATCPMANRLTPETIEEYKRKYPNAPVVLYVNSTAECKTLADVICTSANAVEVVRKIESDVILFGPDRNLAEYVAEKTGKKIFAMPEDGHCPVHQFSENSVDIAKKKHPDARVVVHPECPKPVRDKADYVGSTGQMEKIPEKDTAKTFVIGTEVGMIHKLKKKFPDRNFIPLESAICVNMKKNTLENTLLALETESFEVTLPEDIIEKARRPILKMFEIMG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_ESCF3
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: PG096_VACCW
Sequence: MEVITDRLDDIVKQNIADEKFVDFVIHGLEHQCPAILRPLIRLFIDILLFVIVIYIFTVRLVSRNYQMLLALVALVITLTIFYYFIL
What is the function of this protein?
Early protein involved in virion morphogenesis.  Participates in the formation and elongation of crescent-shaped membrane precursors of immature virions in cytoplasmic factories.
What are the official names of this protein?
Protein OPG096, Protein F3, Protein L2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG096 family.
Protein: DUS3_ASPNC
Sequence: MEPTTAQEQLPAPEQLPAPEANAPKRDPENGDAAADHQAQEPPSKKARLDDSADSNGQTADAPAPRMKGVAPIKPEFIIDQQPTRGQTASDANADDAAEAAHHDGRADEQNGKKKKKKTGQNTNRTFGRSEDAKGLCSSVNFRPEFSPAECTFGEKCRYEHDLRTYLKEHKREDLTTFNGMCPVWDVHGKCFVGWKCRFVGSHSEERETADGRKELVLIEDEERKKKVQRLVPFAGEDGAVNVASMEDKIALARRKMDFPRAGPYSAWLENTSRTIEKELHKRHRAAPVGAETKDGESKDAESKDADSKDEKEENRAMYVEPPFMPSEKRRLYFGPETPALAPLTTQGNMPFRRLCVELGAQFTYSEMAMSLPLIQGNKSEWALMRAHESEMLPPTMLPGADIVQGYDNSKDMKFGAQIAANKPWQAFKATEALAKVTPNLRVIDLNCGCPIDLVFKDGAGSALLEHPSKLEKIIRGMNTVSDQIPITVKIRMGTKDNNPNALKLTERLLLGGYETSLLHHDGAAGAAAITLHGRSRQQRYTRQADWEYISECAALIKRLNEKTDAVTDTIREPDARTQPNGGKVYFLGNGDCYSHVDYDNHINNAGVDAVMLGRGPLIKPWLFEEIQAGQYLDKSATERLAMIEKFCKYGLEAWGSDEHGVGTTRRFLMEWLSFTRRYVPIGLLEHLPPYINDRPPAFRGRNELETLLASANYKDWLKISEMFLGPAHKDFKFEPKHKSNSYDEAEG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase dus3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CXOL1_NPVOP
Sequence: MGVKSALFIMAVFAAANVQYVLAACAETGAVCVHSDECCSGACSPVFNYCLPQ
What are the official names of this protein?
Conotoxin-like peptide 1.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_MSVN
Sequence: MSTSKRKRGDDSNWSKRVTKKKPSSAGLKRAGSKADRPSLQIQTLQHAGTTMITVPSGGVCDLINTYARGSDEGNRHTSETLTYKIAIDYHFVADAAACRYSNTGTGVMWLVYDTTPGGQAPTPQTIFAYPDTLKAWPATWKVSRELCHRFVVKRRWLFNMETDGRIGSDIPPSNASWKPCKRNIYFHKFTSGLGVRTQWKNVTDGGVGAIQRGALYMVIAPGNGLTFTAHGQTRLYFKSVGNQ
What is the function of this protein?
Encapsidates the viral genome into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement.  The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell-to-cell movement and spread (By similarity).
Protein: IOLG_AGRFC
Sequence: MTVRIGVVGTGAIGRDHARRINKVLGGAKIVALSDVNRASAEAVKNDIAPDAVLFATGEELIASPDVEAVLVTSWGATHEQYVLAAIAAGKPCFCEKPLATTAEGARRIVDAEVAHGKRLVQVGFMRRYDAGYVALKQAVDNRIGAPIMVHAAHRNPSVPEQYVTPMAIHDTMIHEIDVLRWLLDDDYVSARVLFPRSAARSHAKLKDPQIVILETAKGTIIDVEIFVNCHYGYDIQCQVVGEDGIASLPEPMSVQTRLGARLQNDILTDWKDRFIASYDVELQDFIHAAAKGTASGPNSWDGYVAAISSDACVAAQETQGAAVAIDLPARPALYQ
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: ZNF76_RAT
Sequence: MESLGLQTVTLSDGTTAYVQQAIKGEKLLEGQVIQLEDGTTAYIHQVTIQKESFSFEDGQPVQLEDGSMAYIHHTPKEGYDPSALEAVQLEDGSTAYIHHPVSVPPDSTILAVQTEVGLEDLAAEEEEGFGADTVVALEQYASKVLHDSPASHNGKGQQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRSYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFRCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSSCGKTYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPSPKPTHIAYLSEVKEESSDIPTQVAMVTEEDGAPQVALITQDGTQQVSLSPEDLQALGSAISVVTQHRSTTLTIPGHQEELATSGTHTVTMVSADGTQTQPVTIITSGALVTEDSSVASLHHQQVALLATANGTHIAVQLEDQQTLEEVISVATSAMQQGAVTLETTESGC
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 76, Zinc finger protein 523.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WNT2_NOMLE
Sequence: MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQYQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSAKDSKGIFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANERFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRCQDCLEALDVHTCKAPKNADWTTPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity).  Functions as upstream regulator of FGF10 expression.  Plays an important role in embryonic lung development.  May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: ACKA_PSEAE
Sequence: MPSRNILVINCGSSSIKFALVNEAHSLFPLHGLAERLGSRDAVLRWKRGGDSDSLMIPNADHRAALAQLLPMVQNAAGGKLHGIGHRVVHGGELFTHATRIDDRVVEAIRATAPLAPLHNPANLQGIEAAMTLFPKLPHVAVFDTAFHQSLPEHAYRYALPEALYREHGVRRYGFHGTSHRYVSHRAAEMAGLAVGDSSWLSAHLGNGSSTCAIVNGQSLDTSMGLTPLEGLVMGTRSGDVDPNLHSHLARTLGWSLERIDSMLNNESGLLGLSDLSNDMRTLEQEREQGHPGAALAIEVFCYRLAKSLAAMSCALPQLDGVIFTGGIGENSPLVRAKTAAHLRLFDLRLDQEANARCVRGVAGPIQAAGHPRVLVIPTNEERQIALDTLALLD
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_STAEQ
Sequence: MLSAQQFLKEFNNVESLDESLYEIVSQICEEVKLQGDKALKNYNLQFDQVETEKLELEQSQLKNAYDMLDNETRDALEQSYQRIKVYQENIKVKQESSQQTECYERYHPIERVGIYVPGGKASYPSTVLMTATLAQVAGVNEITVVTPPQNSGICQEVLAACYITGVHHVYQVGGAQSIAALTYGTETIKKVDKIVGPGNQYVAYAKKFVFGQVGIDQIAGPTEIALIIDESADLDAIAYDVFAQAEHDEMACTYVISENEKVLNQLNTIIQEKLQYVERQDIISQSIANHHYLILAQDTEEACLIMNTIAPEHASIQTRAPEMYIDKVKYVGALFLGHFSPEVIGDYVAGPSHVLPTNQTARFTNGLSVNDFMTRHSVIHLSQKTFNEVAESAEHIAHIESLFNHEKSIHVRR
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: DEOC_YERPY
Sequence: MTTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQQLAGSSVKVCSVIGFPLGAGLTAAKAFEAQAAINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAATPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFSTGGAKEEHVKLMRATVGPVMGVKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1418_KLEP3
Sequence: MKKKTSLSEEDQALFRQLMTGTRKIKQDTIVHRPQRKKVTEVAPKRLLQEQADNSHYFSDEFQPLLNTEGSTKYVRADVSHFELKKLRRGDYSPELFLDLHGLTQQQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHIMAFHQAPKEYGGDAALLVLIEVEEWQPPELP
What are the official names of this protein?
UPF0115 protein KPK_1418.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: ARGB_BACC0
Sequence: MNDYIVVKCGGSMLEQLNDVFFDCIKKLQQQYKVVIVHGGGPEIDAKLKDCNINVEKRDGLRVTPKEVMDVVQMVLCGSTNKKFVMNLQKHNLLAVGCSGCDGKLLQVQPVSEEIGYVGEVSYVETALLKGLINMNYIPVIAPIGIHDNEIYNINADTAAAGIAAALSAKELILITDVDGILHEGKLVKKTDESEIATLIEKGVITGGMIPKVQAALASLKMGVQKISIVNGTKDFTEDTGECIGTTVTRGVSIV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEB_ECO24
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: THII_ACTSZ
Sequence: MKFIIKLFPEIMIKSDSVRKRFIKILTGNIRNILDKHDDSVAVVRHWDFIEVRSKHEENRPHLIELLQCIPGIHHFLEVEERPFTDLHNIFEQTLERMRDELVDKTFCVRAKRRGKHSFSSLEIERYVGGGLNQHIETAKVKLKNPDVTVRIEVDNDKLLFIQARHEGIGGYPIGTQEDVLSLISGGFDSGVSSYMLIRRGSRVHYCFFNLGGAAHEIGVKQMVYHLWNRYGSSHKVRFIAINFEAVVGEILEKIDNGQMGVVLKRMMVRAAGKVAQRFAIEAIVTGEALGQVSSQTLTNLRLIDEAAGTLVLRPLITHDKEQIIAMAKQIGTEDIAKSMPEFCGVISKNPTVKAVRERILAEEEHFDFDILESAVQNAEYLDIRQIAEETAKGVVEIDGVSVLGENDVILDIRSPEETDENPLALENRQVIELPFYKVSSQFGELDQSKNYVLYCERGVMSKLQALYLKENGFNNVQVFVKAK
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLS8_PITHY
Sequence: MAFLKKSLFLVLFLGLVSLSICEEEKRETEEEENDQEEDDKSEEKRFLSLLPSLVSGAVSLVKKLG
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Phylloseptin-H8, PLS-H8, Phylloseptin-10, PS-10.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIHA_SHIFL
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVIVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: SYC_LIMRJ
Sequence: MLTIYNTLTRKKEEFKPLHPGVVNMYVCGPTVYNYIHIGNARSAIAFDTVRRYLEFKGYKVNYVSNFTDVDDKMIKAAAEQGITVPQLAEKYINAFMEDTAAINIEPATLHPRATENITEIIKFVQGLIEKGYAYPKDGDVYYRARKFNHYGQLSGQSLDDLEVGASEHVSADEVNKKEDPLDFALWKAAKPGEISWDSPWGKGRPGWHIECSVMSTKYLGKTIDIHAGGQDLEFPHHENEIAQSEAETGQKFVRYWMHNGFVTIGKDNEKMSKSLHNFITVHEIIKEVDPQVLRFFMATTQYRRPIQYSQANLTDAQNNLNHIQTAFDNLTYREQDADEGDVQEVTDRLEQFHHQFITAMDDDINVQNGIATVYELVKYANVYAQQDNVSLGAIQAIKKELVELMSIFGVKLEASDNQINDEKIKQLIEERNIARKNKDFARSDEIRDNLKKQGIILEDTPQGTRYKKE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_ALIB4
Sequence: MEKLVIATRRSQLALWQSEYVKSRLLEHYPNMQIELQEFVTKGDKILDVPLAKIGGKGLFTKELEVAMLEGSAHLAVHSLKDVPTQFEDGLMLAAVTKRFDPRDAFLSNKYTSLEELPKGAIVGTTSLRRRMALKILRPDIELKDLRGNINTRIAKLNAGEYDAIILAATGIQKLGIENEVKYFSPISTDIMIPSMGQATLGIETTNDPKVLEILKVLNDNNAHIESTVERSFVDTLQGGCQVPIGVKATILDENSIRVQAIVGMPDGSEYISEDITADIEDYETIGQNLAQIFIDQGAKELLEKAEKVAFK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: NAAT1_DROAN
Sequence: MELKPNGNHNNNNAAEKSEDTEKAKAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSICPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSFCREDWQNCVDSRPAEYTENLITGLASNASTLASNLTTPFSNRGVSLLADNETVKLQSSSEIYFLDVVIKEKLDISDGIGSPDWKLTLALLASWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGIIFFLQPQWGELLNPTVWKNAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLNIENIQDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGLKYWKVALGTSMCGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWIYGLQNFCDDIEFMCNRRVSLYWRMCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAGNVAGWLLFGIGAAQFPLWGLWYVSRHREGSFCSSIMASLKPSEKWGPANAEVKREWQIFKSQKAAQRAVQKESSKLGFFWRKITNFCGSNI
What is the function of this protein?
Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids.  Neutral amino acids are the preferred substrates, especially methionine and phenylalanine (By similarity).
What are the official names of this protein?
Sodium-dependent nutrient amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TYSY_LISMF
Sequence: MKQYLDLEKYVLENGTQKGDRTGTGTISTFGYQMRFDLQEGFPIMTTKRVPFKLVVSELLWFLHGDTNIRYLLQHNNNIWNEWAFERFVKSDDYKGEDMTDFGLRAERDSAFKEVYQAEMEKFKARILEDEAFANKYGELGNIYGKQWREWKTSQGETIDQLADLIEMIKTNPNSRRLIVSAWNPEDIPNMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAREVGLEVGEFIHTMGDAHLYNNHIEQVKEQLSRTPHKLPKLVLSDKPATIFDFDVADISLDGYNPDPAIKAPISV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_MYCTA
Sequence: MSVPRVGVLALQGDTREHLAALRECGAEPMTVRRRDELDAVDALVIPGGESTTMSHLLLDLDLLGPLRARLADGLPAYGSCAGMILLASEILDAGAAGRQALPLRAMNMTVRRNAFGSQVDSFEGDIEFAGLDDPVRAVFIRAPWVERVGDGVQVLARAAGHIVAVRQGAVLATAFHPEMTGDRRIHQLFVDIVTSAA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DCD_THEGJ
Sequence: MMLPDWKIEKEILIEPFSKESLQPAGYDLRVGKEAYVEGKLIDVEEAGNVIIPPKKHALILTLERVKLPDDVMGDMKIRSSLAREGILGSFAWVDPGWDGNLTLMLFNASNEPVVLEYGERFVQIAFIRLEEPAKRPYRGNYQGSRRIALSKRRVRK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: OPGC_ECOL5
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPRLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDPAS_METJA
Sequence: MFYRLLFASLWYILPAYVANASACIFGGGTPVDLGKNFIDGRRLIGNGVTYRGCIFGILCGTLVGLIQGILVDFNIFNSLDFYGTVLDHVILAFFLSVGAIVGDAVGSFIKRRLNIERGKPAPLLDQLDFVIGALAFGYIVAPIPYEMIIIICLFTVFVHLLGNIIAYKLGIKDVWW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS8_BORBR
Sequence: MSMSDPIADMLTRIRNAQQVDKTTVTMPASKLKVAIATVLKDEGYIDGYSVKGTQAKPELEITLKYYAGRPVIERIERVSRPGLRIYKGRTSIPQVMNGLGVAIVSTSRGVMTDRKARANGVGGEVLCYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL6_SPHAL
Sequence: MSRIGKKAVEIPSGVTAAIDGGQLSVKGPKGTLAMSLSDNIKYEVGDGSISVQPANDSREARAFWGMQRTLVQNLVTGVTEGFTKVLEITGVGYRANAQGKNLKLQLGYSHDVDFAVPDGIEIKTPDNTTIEISGIDKQQVGQVAAEIRRWRKPEPYKGKGIKYRGEYIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CPLX3_BOVIN
Sequence: MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEERASVLGQLASLPGLDLGSLKDKAHSTLGDLKQSAEKCHIM
What is the function of this protein?
Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity).  Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity).  Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity).  Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity).
What are the official names of this protein?
Complexin-3.
What is the protein family that this protein belongs to?
Belongs to the complexin/synaphin family.
What are the subcellular locations of this protein?
Synapse. Cell membrane; Lipid-anchor. Note=Enriched at the synaptic terminal (By similarity). Localized at glycinergic synaptic contacts of AII amacrine cells with OFF cone bipolar cells in the OFF sublamina of the retina inner nuclear layer (By similarity).
Protein: UGPC_CUPMC
Sequence: MAKLSLRNVQKTYAGGTQVVHGIDMEIADGEFIVIVGPSGCGKSTLLRMVAGLETITGGEIHIGDKVVNDLEPAARDIAMVFQNYALYPHMSVYDNMAYGLKIRGMSKGEIEQRVKHAAGILELASLLDRKPRALSGGQRQRVAMGRAIVREPSVFLFDEPLSNLDAKLRVQMRLELKDLHRRLKTTSLYVTHDQVEAMTLADRMMVLNGGRVEQIGTPLEVYARPASTFVAGFIGSPPMNLVPVARNGSGQGVAQMRVQPKDGQAAATLGHLPMGLHLPEQALMGLRPEHIEPCAVHEAIAELDVRVVEALGADSFAYGSLGGQPIVVRLDSQTQVRAGDKLPITASAEHLHFFDVQSGKRIEAQA
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.