PharMolix/UniProtQA huggingface dataset:
Protein: SDD1_YEAST
Sequence: MANDGIQRNDNRKGFKTVQFSAYSKEIDVIMKKISFLERNITQQLDTLPHFPKTLPPNHKDCVSRKHRARRGWSSQLKNLLGIYSKEEIFTLDNLAATLHDQVLKLQATLFPNAILKQVHLDNANIENKRILKEITYKYLSNENCKEENKFGTFIVKRIFFGDLSLGVSVLINRIAFESATSSIMVVRSSFIESDFFYEDYLIFDCRAKRRKKLKRKILFISTTMNFNYQTKV
What is the function of this protein?
Acts as a endogenous target of the ribosome quality control (RQC) pathway (PubMed:32203490).  During translation, the nascent chain has a propensity to stall ribosomes, thereby stimulating activation of the RQC pathway (PubMed:32203490).
What are the official names of this protein?
Uncharacterized protein YEL057C, Suppressor of degenerative death.
Protein: YPFN_SALAR
Sequence: MDWLAKYWWILVLVFLVGVLLNVIKDLKRIDHKKFLANKPELPPHRDFNDKWDDEDDWPKKDQSKK
What are the official names of this protein?
UPF0370 protein YpfN.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RECR_STRP6
Sequence: MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFAKNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHGYYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ILVC_CAMHC
Sequence: MAVTVYYDKDCDLSLIRSKKVAMIGFGSQGHAHALNLRDSGVDVVVGLKKGGKSWAKAEAMNFKVKSVVEATKEADVIMILTPDELQADIFASEIKDNLKEGDTIAFGHGFNIHYGQIVPPKGVDCIMVAPKAPGHTVRSEFVKGGGVPNLIAVSQNASGQAKELALSYASAIGAGRTGIIETTFKDETETDLFGEQAVLCGGLCALINAGFNTLTEAGYEPEMAYFECLHEMKLIVDLIYQGGMSDMRYSISNTAEYGDYISGKKVINEDSKKAMKEILGSIQDGSFAKDFILERKAGYARMNAERKIADASLLNKTGEKLRAMMPWIKNGKLVDKDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LPLA_ECO55
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITKAFFAHYGERVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFSWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALTGRLQGGLYRADMLQQECEALLVDFPDQEKELRELSTWIAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNU_FLAPJ
Sequence: MIFQNTLEFAQQLDNQDELKEYKNEFIFPQHEGKNVIYFTGNSLGLQPKSARNYVDEVMNDWANLAVEGHFYADKPWWDYQERFANPLSKIVGAKPLEVTVMNTLTVNLHLLMVSFYRPTKKRYKIICEEKAFPSDQYMFQSQVNFHGYKPEDAIVEIKRREGEHNIRLEDILSKIEAVGDELALVLFGGVNYYTGQVFDMKTITEAGHKQGAKVGFDLAHAAGNIKLELHDWNVDFAAWCSYKYMNSGPGNASGCFVHEKHHSDSNLPRFAGWWGHNKERRFKMEPTFDPVHGADGWQISNLPILSLAPYLASVEMFAEVGIEKLIRKRNQITAYLEFILHEIDKEVKGHFEILTPTNQEERACQLSVFLHGEGRSLFDYLMKNGVVTDWREPNVIRLAPVPLYCSFEDMYNFGQILKKGILEN
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: GLNE_CORDI
Sequence: MRKTLPSIGALGFSNTNAEKDLCCLGWYSNDPDTVVDAPEQAAEILWHLSGTADPDLALNTIIRLMEALGEQKGQLHNALRTDPELRVKLFSLLGASTALGDHLVAHPHTWPELQRPMPTRQEMFRLMLGSVGAARASFSSESQQPQGSDSDSEFSFGADLSADDTANTDLSTPGTYRAEITGERAEVALKTTYRSLLLRIAAADLAGTYPEDIHRTGLPEVPFVTVTKALADLADAALTAALAVAVAHVYPEGEVDTHLAVMAMGKCGAQELNYISDVDVIFVAEPVTPKAIRLAGEFIRIGCACFFEVDAALRPEGKHGVLVRTLDSHVAYYKRWAETWEFQALLKHRPMTGYMPLGQAYSEKLQPMVWEASQRESFVDNVQRMRRRVLENVPAKLKNLELKLGEGGLRDVEFAVQLLQLVHGRSDESLRTLSTIDALNALIEGGYVGREDGAELIRAYEFLRLLEHRLQLQKVKRTHTMPEATKTKQLRWLARAAGFKTSKLASATDEMNAMLKTSRLHISSLHRKLFYRPLLDSVVNISVGTLKLSPAAAKLQLAALGYVFPDRAMDHLHALAAGGSRKAKIQAMLLPTLMEWLSETAEPDAGLLNYRKLSDAAYDRTWFLRMLRDEGVVGQRLMRILGNSPYTADLIISAPDIVKQLGDGATRPKLLETSEDRVTKSIVAAAARHDDPDVAIAVARSLRRAELARIASADLLQMLSVQQVCRRLSYVWDAVLEAGLQAEIRASLIGSTGDKNSVPPARIAVIGMGRLGGSELGYGSDADVMFVCEPTEGVSDEAAVKWAIGVCDSMRSRLAKPSGDPPLDVDLGLRPEGRSGAVVRTLESYKQYYERWGEVWEIQALLRADFIAGDQELGARFLEMIEPLRYPEAGVSQKVIREVRRMKARVDNERLPRGADRNTHTKLGRGALTDVEWTVQLLTMMHAHEFQDLHNPSTLDSLDVIEKHAVIEPEKVEVLRQAWLTATRARNAIVLVRGKRVDQLPQQGTQLAAVAGAAGWEPSDSQQYLDHYLKVTRRARQVVDEVFWGVDSIEHDY
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: RL13E_SULIY
Sequence: MEFPKALIKRPNYHFEYPHKRKDKRIGRGFSIGELEKAGLNINNARKLGIIVDIRRKSVHEENVEVLKKFLEQLSNQKS
What are the official names of this protein?
50S ribosomal protein L13e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
Protein: AACS_DANRE
Sequence: MSKDTEAKSEEIMESKVLWYPDSKRNTQTDRFRTLVNREFGLNLANYNDLYQWSVDSYPEFWAQVWKFCGITCSKMYEEVVDVSKRISDVPEWFKGSRLNYAENLLKHKDQDKVALYAASEAKEEIVKVTFGELRRDVALFAAAMRKMGIKIGDRVVGYLPNGVHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRISQIQPKLIFSVAAVVYNGKQHDHMEKLQNVVKGLPDLKKVVVIPYVRSRQETDLSKIPNSVFLEDFLATGKEGDQDPQLEFEQLPFSHPLFIMYSSGTTGAPKCMVHSAGGTLIQHLKEHILHGNMTFNDVIIYYTTTGWMMWNWLISSLAVGASVVLYDGSPLVPSANVLWDLVDRLGITIFGTGAKWLAVLEERDQKPASTHSLQTLHTLLSTGSPLKPQSYEYVYSCIKNNVLLGSISGGTDIISCFMGQNMTVPVYRGEIQARNLGMAVESWSCEGKPVWGESGELVCLKPIPCQPTHFWNDENGSKYHKAYFSTFPGVWAHGDYCKINPKTGGVVMLGRSDGTLNPNGVRFGSSEIYNIVEAFDEVSDSLCVPQYNSDGEERVILFLKMGPNKSFSQELVGKIRGAIRVALSARHVPALILETKDIPYTISGKKVEVAVKQVIAGKEVTQRGAFSNPDSLDLYKNLPELQNF
What is the function of this protein?
Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity).  Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity).
What are the official names of this protein?
Acetoacetyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: G3P1_METBF
Sequence: MVKAKIAVNGYGTIGKRVADAVRAQDDMEVIGISKTKPNYEAAVAHQIGYDIYAPAANLEAFEKAGMPAAGTIEEMVEKADLVVDCTPGGIGEKNKPMYEKAGVKAIWQGGEDHSLAGFSFNAICNYEQAVGRDLVRVVSCNTTALCRAIYPIDKELGVKKARVVLARRATDPNDVKKGPINAIVPDPIKLPSHHGPDVKSVLPQINITSAALKIPTTLMHVHTVNMEVEKDCTVDDVKNIFGSQPRIRFVGQGMSSTAEIMEFARDMKRPRNDMWENCIWPESITVGDKELYFFQAVHQESIVVPENVDAIRAMMEFESDGAKSIEKTNKAIGLSKK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 1, GAPDH 1, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLA23_BOTDP
Sequence: NLWQFGRVFVYPDVLCKGCYCGWGGRMDIYTYSRCCFVHDCCYGK
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 3, BdsPLA2 III, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CARB_STAA1
Sequence: MPKRNDIKTILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYRVILVNSNPATIMTDKEIADKVYIEPLTHDFIARIIRKEQPDALLPTLGGQTGLNMAIQLHESGVLQDNNVQLLGTELTSIQQAEDREMFRTLMNDLNVPVPESDIVNTVEQAFKFKEQVGYPLIVRPAFTMGGTGGGICHNDEELHEIVSNGLHYSPATQCLLEKSIAGFKEIEYEVMRDKNDNAIVVCNMENIDPVGIHTGDSIVVAPSQTLSDVEYQMLRDVSLKVIRALGIEGGCNVQLALDPHSFDYYIIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMLNPITGTSYAAFEPTLDYVISKIPRFPFDKFEKGERELGTQMKATGEVMAIGRTYEESLLKAIRSLEYGVHHLGLPNGESFDLDYIKERISHQDDERLFFIGEAIRRGTTLEEIHNMTQIDYFFLHKFQNIIDIEHQLKEHQGDLEYLKYAKDYGFSDKTIAHRFNMTEEEVYQLRMENDIKPVYKMVDTCAAEFESSTPYYYGTYETENESIVTDKEKILVLGSGPIRIGQGVEFDYATVHAVWAIQKAGYEAIIVNNNPETVSTDFSISDKLYFEPLTEEDVMNIINLEKPKGVVVQFGGQTAINLADKLAKHGVKILGTSLENLNRAEDRKEFEALLRKINVPQPQGKSATSPEEALANAAEIGYPVVVRPSYVLGGRAMEIVDNDKELENYMTQAVKASPEHPVLVDRYLTGKEIEVDAICDGETVIIPGIMEHIERAGVHSGDSIAVYPPQTLTEDELATLEDYTIKLAKGLNIIGLINIQFVIAHDGVYVLEVNPRSSRTVPFLSKITDIPMAQLAMRAIIGEKLTDMGYQEGVQPYAEGVFVKAPVFSFNKLKNVDITLGPEMKSTGEVMGKDTTLEKALFKGLTGSGVEVKDHGTVLMTVSDKDKEEVVKLAQRLNEVGYKILATSGTANKLAEYDIPAEVVGKIGGENDLLTRIQNGDVQIVINTMTKGKEVERDGFQIRRTTVENGIPCLTSLDTANALTNVIESMTFTMRQM
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: YFEC_ECOL6
Sequence: MTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKARLVHVNEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLLREGIIGLLQRLGIRDSK
What are the official names of this protein?
Uncharacterized protein YfeC.
What is the protein family that this protein belongs to?
To E.coli YfiI and P.aeruginosa RluD.
Protein: PYRR_LACLM
Sequence: MARKEIIDEITMKRAITRITYEIIERNKELDKLVLIGIKTRGVYLAKRIQERLQQLEGLEIPFGELDTRPFRDDKQAQEDTTEIDIDITGKDVILVDDVLYTGRTIRAAIDGIVKLGRPARVQLAVLVDRGHRELPIRADYVGKNIPTGHDEEIIVQMSEHDGNDSILIKRED
What is the function of this protein?
Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines, probably by binding to specific sites on pyr mRNA.  This probably disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.
What are the official names of this protein?
Pyrimidine operon regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: ADDB_STAAW
Sequence: MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDVLQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVFLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYIAMTRARQDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: SYLC_SCHPO
Sequence: MATTEPSVEQLETKTAKLKLENTTKRDTLIELEKKYQQKWQEEKAFEVDAPLEDVPIDELRKKYPKFFGNMPYPYMNGALHLGHAFTLSKVEFTTAFERLNGKRVLFPMGFHCTGMPICASADRLSREIEMFGPSFDVPEEKEEEVEVEVKTPNAREDVTKHSGKKSKAAAKTAAVKYQFQIMESLGVPRTEIHKFADAKYWLSYFPPLCQRDCTEFGLGIDWRRSFITTDVNPYYDSFVRWQVNHLHDSGKIKFGERYTVYSIKDGQPCMDHDRKSGEGVGPQEYTGIKMEVLEFPEAARKALQSIDLSNKKVCMIAATLRPETMYGQTNCYVGPNITYGIYESNVPNELFICTRRAANNMAYQKLSKERGVVSELGTIKGQDLIGALVNAPLSVHKQVYVLPMETVLATKGTGVVTSVPSDSPDDFATLTELRKKAEFYHLNPEWMKYEAVPIIRTPSYGDMCAEFLCKKLKIQSPKDVKQLAQAKELAYKECFYQGTMIIGKYSGEKVETAKPKVRKELIDQGLAFVYNEPEGQVISRSGDDCIVALCDQWFLDYGEASWKAVTEKALDRLNTFSPEVRNGFLKTLDWLSQWACARSYGLGTRLPWDPQFLVESLTDSTIYMAYYTICHLLHSDVYGKVPGALNIKPEQMTPEVWDHVFRQAPKPKNTSISDEALARLCREFQYFYPFDIRASGKDLVPNHLTFCLYTHTAIFDEKYWPKGIRANGHLLMNGEKMSKSTGNFMTLHEATKKFGADATRLALADAGDTVDDANFEEALANSAILRLYTQEAWCKEMMENLDNLRTGPYNFHDKVFENEINQLIESSREAFSATLFKAALKSCFYDLQNARDWYREVTADRKMHRDLVCRWIETQVLLLATFAPHWSEHIWLTTLKKPQSIHVSGRFPQVSSPVNTALSNSLLYIRTLSRVIREAEAAQLKRQKKGKGMLFDPSKPKRLTVFVAEKFPEWQAQYVALLQKYYNESENKFDDKAIISSVDKKEMKRAMPFIQQFKQSVINRGEHVSANSIFSRELGFNELEVLREVKPYLVRNVGIQELRIVLLQKPADKSSAAIGLVESGSDAGATVEIAPNFANTVPGQPTFLFENVSA
What are the official names of this protein?
Putative leucine--tRNA ligase, cytoplasmic, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAS6_DANRE
Sequence: MTELLFNKRLQVLVKSKDTDERRSVIRVSIELQLPSSPVHRKDLVVRLTDDTDLYFLYNLIISEEDFQSLKVQQGLLIDFTSFPQKFIDLLEQCICEQDKESPRFLLQLSSSSSAFDHSPSNLNIVETNAFKHLTHLSLKLLPGSDTDIKKYLASCLSSVKEEKQQLQQKLRKTEEDLTRQLNYAQQTLSEKSRELDKLRSEWTSQTTSLSSRHMQDLTAEREKALETQSRLQQQNEQLRQELESSHHRSTQQLQTKVSELETANRELIDKKYKSDSTIRDLKAKLTSLEEECQRSKQQVLSLRRENSALDSECHEKERLLNQLQTRVAVLEQEIKDKDQLVLRTKEVLEATQQQKNSVEGNAESKQLQISKLESTVKSLSEELIKANGIIKKLQADLKALLGKIKVKNSVTVPQEKILQETSDKLQRQQRELQDTQQRLSLKEEEAAKLKEQLEATVQKLDESREVLKTNENVITWLNKQLNENQLSRKQETVAMFETPAAALRSAAVPHNMAFPITSTINSKYPLALSCVSSGSRSVLTSSNGPKVQFNPMSVKPSAAEVSPAAFSQPANKENSEPVGLDSKYFERRDDSIPLRGLLPSMHLNREVPKPLNTAAAKATPSAFFPG
What is the function of this protein?
Central scaffolding component of the centrioles ensuring their 9-fold symmetry (PubMed:21273447).  Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells (By similarity).
What are the official names of this protein?
Spindle assembly abnormal protein 6 homolog.
Protein: UL24_EHV1
Sequence: MKRRQRLTARSRLRAGIRCHNRFYNAMVQDLASAKRNGVYGERLAPLFSELVPAETLKTALGVSLAFEVNLGQRRPDCVCTVQFGKGSDAKGVCILIELKTCRFSKNMNTASKNLQRKGGMRPVHDSCRLLARTLPPGSGEIVLAPVLVFVAQRGMRVLRVTRLSPQVVYSNAAVLSCTISRLAEYAPPVSAKSTRRRCVAKGTKAKAFSTKAAAEPVPSITPAQPSAAAAVVSLFPAAVPANTTNAAAVHQPVAVSHVNPLAWAASLFSPK
What are the official names of this protein?
Protein UL24 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL24 family.
Protein: AROQ_HISS2
Sequence: MSRYAKILLLNGPNLNMLGKREPTHYGNLSLEDIEQRMQELAQQHQLELSCFQANSEEKLIDKIHQSFHLIDFIIINPAAYTHTSVALRDALLSVSIPFVEVHLSNIHRREPFRHHSYLSDIAEGVICGLGAQGYEFALQYASNYLKKIK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: GATA_SYNE7
Sequence: MASIRELHSQLVRKERSAVEIAEAALQRIETLEPQLKSFLHVTADQAIAQAKAVDQRIAAGEEISLLAGIPIGIKDNLCTRGIPTTCASKILQGFVPPYESTVTQRLAEAGAVAVGKTNLDEFAMGSSTENSAYQTTANPWDLTRVPGGSSGGSAAAVAADECVVALGSDTGGSIRQPAAFCGVVGLKPTYGLVSRYGLVAYASSLDQIGPFSRSVEDTAILLGAIAGHDPKDATSLKVEVPDYTQFLKPSLAGIKVGVITETVTDSPAGQAMQAALEVLQGLGAEIREISCPRFAYGLPAYYIIAPSEASANLARYDGVKYGYRVEEAETLIDMYCRTRAEGFGSEVKRRIMIGTYALSAGYYDAYYLKAQKVRTLIKQDFEAAFAEVDVLVSPTTPTTAFKAGEKTADPLSMYLSDLMTIPVNLAGLPGLSLPCGFDEAGLPYGLQIIGNVLREDQVLHTAYAYEQATEWHLRQPAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: DHN1_MAIZE
Sequence: MEYGQQGQRGHGRTGHVDQYGNPVGGVEHGTGGMRHGTGTTGGMGQLGEHGGAGMGGGQFQPAREEHKTGGILHRSGSSSSSSSEDDGMGGRRKKGIKEKIKEKLPGGHKDDQHATATTGGAYGQQGHTGSAYGQQGHTGGAYATGTEGTGEKKGIMDKIKEKLPGQH
What are the official names of this protein?
Dehydrin DHN1, M3, RAB-17 protein.
What is the protein family that this protein belongs to?
Belongs to the plant dehydrin family.
Protein: SUCC_SHIBS
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPQLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQLDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKVVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PIMC_MYCTO
Sequence: MRVVQVANFYGPRSGGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPAKHIPYTGGYRAVMPGAVRTVLETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREEFDRIGATNTVTVPLGVDLKTFHPRRRCARVRQHWATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGPLRARLERKATGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLACGTPAVVSRTSALTEIITADSGACADNRPEAIAHAVRTIVSRPERHRRRCARRRAEIFTWQRAAASMLATLGAMAVSTRCGDTQDTA
What is the function of this protein?
Catalyzes the addition of a mannose residue from GDP-D-mannose to the position 6 of the alpha-1,6-linked mannose residue of the triacyl phosphatidylinositol dimannoside (Ac3PIM2) to generate triacyl phosphatidylinositol trimannoside (Ac3PIM3).
What are the official names of this protein?
GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase, Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase, Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase, Phosphatidylinositol alpha-mannosyltransferase, PI alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
Protein: RN165_MOUSE
Sequence: MVLVHVGYLVLPVFGSVRNRGAPFQRSQHPHATSCRHFHLGPPQPQQLAPDFPLAHPVQSQPGLSAHMAPAHQHSGTLHQSLTPLPTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRRLVSHPRRNQDRVSVHPHRLHPSFDFGHQLQTPQPRYLAEGTDWDLSVDAGLSPAQFQVRPIPQHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYEELLQLEDRLGNVTRGAVQNTIERFTFPHKYKKRRPQDSKGKKDEGEESDTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as a regulator of motor axon elongation (PubMed:23610558).  Required for efficient motor axon extension in the dorsal forelimb by enhancing the transcriptional responses of the SMAD1/SMAD5/SMAD8 effectors, which are activated downstream of BMP (PubMed:23610558).  Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL (PubMed:23610558).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF165, Arkadia-like protein 2C, Ark2C, RING finger protein 165.
What is the protein family that this protein belongs to?
Belongs to the Arkadia family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BGAL_THEP3
Sequence: MGRDVLNFNVDWLYIPEDLNDAYKFDFDESNFEVVSLPHANKTFPHHYFKEEDYRFVSWYRKHFKVDERYKGKKVYIHFEGVITVAKVYVNGEFVGEHKGGYTPFEFDITEYIKYGNFENLIAVQVDSREHKDIPPEGHLVDYMLFGGIYRNVWLKILNDTHIKDVYFVVDKLQDSVAEISITTTIAGKEISNGKILTEVINKEGVVCSSVVTDIKEMQKEIVQQIKMDNPLTWHPDHPYLYNVSVKLIAENEILDNYTFKTGIRTVEFRDDGKFYINGEPLKLRGLNRHQTFPYVGGAMPDRVQRKDADILKYELGLNYVRTSHYPQAVSFLDRCDEIGLLVFEEIPGWQHIGDENWKNIAKENLKEMILRDRNHPCIFMWGVRINESLDDHDFYKEMNEIAHKLDRSRPTGGVRYLRDSEKLEDVFTYNDFIYNLEGKIQLPNHKKYMVTEYMGHMYPTKSYDNLNRLITHARLHALIQDKQYGIPNMAGASGWCAFDYNTTSAFGSGDNICYHGVCDIFRLPKFAAHFYRSQADPHLYGPYVFIASYLIPSFEEENGDKLLVFSNCEEVELYINDKFVKRQMPNRVDFPSLPHPPFEFSMKECGINYMEVRVNNASITAIGLIDGKEVARHTLRPYGKPHKLILSCDDNEIMADGADCTRVVVSVVDENGSILPYANIPVSFEIEGEGKLIGENPLTLEAGRGAVYVKSTRKPGEIILKAKSHYVAEESNVSIKTKSIGY
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: HAUS1_RAT
Sequence: MAALEEKASQVAEWLKKIFGDHPIPQYEMNARTTEILYHLSERNRVRDRDVNLVIEDLRQKASEYESEAKRLEDFLMESVNFSPANLSNTGSRFLNALVDSAIALEIKDTSLASFIPAVNDLTSDLFRTKSKSEEIKLELGKLEKNLTATLVLEKCLREDLKKADVHLSAERAKAEGRLQNMDFLKAKAAEFRFGIRAAEEQLSSRGMDASLSHRSLVALSDKLSELKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDAIEAELTKKVDMMEL
What is the function of this protein?
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
What are the official names of this protein?
HAUS augmin-like complex subunit 1, Coiled-coil domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the HAUS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes with the spindle poles in mitotic cells. In interphase, localized at the centrosome and diffusely in the cytoplasm. Localizes to mitotic spindle microtubules (By similarity).