PharMolix/UniProtQA huggingface dataset:
Protein: ADDA_LACPL
Sequence: MSEGTNYTPSQQAVIAQQGNNLLVSASAGSGKTTVLIERIMRKILAGTNIDQLLVVTFTNLAAKHMKQKLESQINKRISQLMTDNPAQTTASPAIRQLRQQLNLLGVANISTLDAFCLRVIQRYYYVIDLDPVFRLLTDNTEGLLIRDQVWDSVREQLYDEDGTLFDLLTANFSNDRSDDGLSRLIFRLFDFAQSTPDPEGWLSKLPEPYQVDEEALTASAFYQQQLLPLLINEVDGMQMKLRQAQKVATDADLVPKTLEVLATAQKTLTTLREQLATASWNELRTQVATFKIGALKKTYKDEPEKTARAKTMGTFVDGVKKQMTTLSETYFAADEQQVLDIMVGAKSIVTELVDATKQFKTAFAAEKRRRHVLDFSDLEHLTLQILTSDNESSQAALAQLRAQFEEVMVDEYQDINSLQESILQLLARDQPGNMFMVGDVKQSIYQFRLADPLLFLHKYHDFGTNPEHGERIVLAENFRSVANVDHLTNLIFSQLMDAPVGQIDYDEAAYLKYGPKDYPADMPQTTNLLLYQTETDKSTEDVSTDETNFSIDDPAVGSITMVAQKILALKAQDKPIYERANGEYRPFRYSDVALLVPTRNHNLTIIDVFKRYHIPVVVNDAQNYFQTTEIRIMMALLSIIDNPYQDIPLVAVLRSPIVGLDENQLVYLRIQNKTSDYFQAVQDFYHHYPTGPATEYGDQVYAKIETFLTQLTEFRDLARRNQIVTLIWQIYERTGFLDYVGGMPAGKQRQANLHALYERAYTYEQGSFKGLFQFVRFIRRMQEKDQDLAAAVAETDAEAVNVMTIHGSKGLEYPVIFVMDMDKQFNQTDTRSSALLDREAGIGITYLDPETRVKYPTLPQVVTKQVVSKKMRAEEMRKLYVAMTRAQQQLYLVGTIKDIDTATEKWRQAFASDGRVLSAQARIAATNQLDWVGMAVMRHPAMKAYWGDEWPNYELTDDPTKLAVELGDATTVLAEQSEAVTDTQPDALELVEQQVTIDVDQVTRDYLTTLLNFHYPHQASTTTTAYQSVSEVKRIFEDPDTPLMNANPTVSQRRSRPTSRFVTGSLELPQFLQTTQAPTSAEVGSATHLVLEQLDLTKPVNETTVQSTIDGLVANRVLTTNVAKLIAVDTIVAFYQSALGSQILDNPAKVHREVPFSLLIPARQIFDVDEHETGKVLIHGIIDGYLETADGLTLFDYKTDHVKRPEDLKTRYAGQVKLYAAALASMYPGKVTKQYLYSLPQQVFVPVN
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: LYS4_CANAL
Sequence: MMLRFRSFSTTTHLLRGQNLTEKIVQKYAVGLQPSSKKVYSGDYVTIKPAHCMSHDNSWPVATKFMNLGASKVKDNRQIVCTLDHDVQNKSEQNLTKYTNIEKFAKSQGIDFYPAGRGIGHQIMIEEGYAFPLNLTVASDSHSNTYGGIGALGTPIVRTDAASIWATGQTWWQIPPVAKVELIGQLPKGVTGKDIIVALCGIFNNDEVLNHAIEFVGDDAISKLPIDYRLTIANMTTEWGALSGLFPVDETLVEFYQNRLKKLNKPDHPRINNQTIDQLINNKLTSDNDAVYAKHLQIDLSSLSPYISGPNSVKISNSLYDLSQQNIAINKAYLVSCTNSRLSDIQAAADIIKGHKVNPNVEFYVAAASSLVQKDAEQSGAWQTILDAGAKPLPAGCGPCIGLGTGLLKDGEVGISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGGPEELNGEPVKQAPRIIKSIETESNSANEAESTSEEASGSIDILPGFPQSIEGELILCNADNINTDGIYPGKYTYQDDITKEQMAKVCMENYDSQFYSKTKPGDIIISGYNFGTGSSREQAATCILARGMKLIVAGSFGNIFSRNSINNALLTLEIPDLINKLRQQYEGNDELTIRTGWFLKWDVTKAQVTVVDGDDNLILTQKVGELGTNLQDIIVKGGLEGWVKSELKTNQ
What is the function of this protein?
Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Homoaconitase, mitochondrial, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SUR8_DROWI
Sequence: MNLCSSGATASASSTSLSSTGQAERNGGGKGGDGSGGGGGGGSSSNQNGSSEAINCFGGGPEPVSNLNSTINGGGGVGGAKTNSNTTANTTATSSNSTSNGQQGHTQHNENTATMPPETRPKVVTVKHPESNKPKPTTKKSKPIQADQDVIKALQRCRDEGIKRLDLSKSSITVIPNTVKECVHLTELYLYSNKIGQLPTEIGCLVNLRNLALNENSLTSLPDSLQHCNQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRFNRITTVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGLRYNRLTSVPASLKNCKSMDEFNVEGNGITQLPDGMLASLNGLTIITLSRNQFTSYPTGGPAQFTNVYNINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQTNQITMLPRSIGHLSQLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLSTIPPEIQAGGPSLVLQWLKMHSPYRQM
What is the function of this protein?
Acts as a Ras effector and participates in MAPK pathway activation.  Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).
What are the official names of this protein?
Leucine-rich repeat protein soc-2 homolog, Protein Sur-8 homolog, Protein soc-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
Protein: HIS2_THET2
Sequence: MDLSAVRFDEKGLVPVVVQDARTGEVLTLAYANREALEETLRTRRSTFFSRSRQALWRKGETSGHTQEVVEVLLDCDGDAVVYRVLPQGPACHTGERTCFHRALLEGEKDLGFVVGQVYATIKERLRTLPEGSYVARMHHAGLDRILKKIGEEAGEVILAAKNQNPEELRHEAADLLFHLLLTLAELGLTPEDLAKTLWERHRPRSPYDGSHGN
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_HYDCU
Sequence: MARIAGVNIPVNKHIVIGLRSIYGVGQTTAQKICADVNIDPTTKVRELTEEQLEALRSEVTKFKIEGDLRRDVTMNIKRLMDMGCYRGIRHRRSLPLRGQRTKNNARTRKGPKKPIKR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: DDA1_PONAB
Sequence: MADFLKGLPVYNKSNFSRFHADSVCKASNRRPSVYLPTREYPSEQIIVTEKTNILLRYLHQQWDKKNAAKKRDQEQVELEGESSAPPRKVARTDSPDMHEDT
What is the function of this protein?
Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex.
What are the official names of this protein?
DET1- and DDB1-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDA1 family.
Protein: CAH8_MOUSE
Sequence: MADLSFIEDAVAFPEKEEDEEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGQEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQMQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ
What is the function of this protein?
Does not have a carbonic anhydrase catalytic activity.
What are the official names of this protein?
Carbonic anhydrase-related protein, CARP, Carbonic anhydrase VIII, CA-VIII.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
Protein: RIMO_SYNS9
Sequence: MTSTTTQPTTQPMAKPKVAFAHLGCEKNRVDTEHMVGLLAEAGYGVSTDEEDASVVVVNTCSFIQDAREESVRTLVGLAEQGKELIIAGCLAQHFQEELLESIPEAKAIVGTGDYQHIVDVLQRVEAGERVNRVSAVPSFVGDEHLPRQRTTDQAVAYLKVAEGCDYRCAFCIIPKLRGDQRSRPIESIVAEAHQLAEQGVQELILISQITTNYGLDLYGKPKLAELLRALGEVEIPWIRVHYAYPTGLTASVVAAYRDVPNVVPYLDLPLQHSHPDVLRAMNRPWQADVNERLLNEIREQLPDAVLRTTLIVGFPGETEEHFQHLKHFLETQRFDHVGIFTFSPEDGTAAADLPNRVDPDVAQARKDALMALQQPIAAERNQRWVGKTVDVLIEQHNPQTGEMIGRCARFAPEVDGEVHVQPGDDGQQAAPGSFVPVKITGADIYDLTGHIVGARSMVAEARVKD
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APC16_BOVIN
Sequence: MAASSSSSSAGGVSGSSVAGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 16, APC16, Cyclosome subunit 16.
What is the protein family that this protein belongs to?
Belongs to the APC16 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore.
Protein: SUS1_TULGE
Sequence: MTERRLTRIHSIKERLGDSLSHHPNELLALFSRFIKQGKGMLERHQLLTEYESVIPEADREKLKDGVFEDTLRASQEAIVIPPWVALAIRPRPGVWEYVRVNVNELAVEECSEYLKFKEDLVDRSSQSNFVLEMDFEPFNANVPRPSLSKSIGNGVQFLNRHLSSKLFHDKESLYPLLNFLREHNYKGTTLMLNDRLQSLSALQTALRKADRYLLSISKDTPYSEFNHSFQVLGLEKGWGDTASRVSENIHLLLDLLEAPDPSTLEKFLGTIPMVFNVVILSPHGYFAQANVLGYPDTGGQVVYILDQVRALETEMLLKIKQQGLDITPRILIVTRLLPDAVGTTCGQRLERVLGTEHTHILRVPFRTDKGILRKWISRFEVWPYLETYAEDVAHELAGEMQATPDLIIGNYSDGNLVASLLAHRLGITQCTIAHALEKTKYPNSDIYLKKFDDQYHFSCQFTADLIAMNQSDFIITSTFQEIAGSKDTVGQYESHTAFTLPGLYRVVHGIDVFDPKFNIVSPGADMSIYYPYFEQEKRLTALHAEIEELLYSSVENEEHKFVLKDRNKPIIFSMARLDRVKNMTGLVELYGKNDRLKELVNLVVVAGDHGKESKDLEEQAELKKMYKLIEEYKLQGHIRWISAQMNRVRNGELYRYIADTKGAFVQPAFYEAFGLTVVESMTCGLPTFATCHGGPAEIIVHGVSGFHIDPYHGDKASEQLVSFFEKCKEDPAHWEKISQGGLQRIYEKYTWKLYSERLMTLAGVYGFWKYVSNLDRRETRRYLEMFYALKYRNLAKSVPLAIDN
What is the function of this protein?
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
What are the official names of this protein?
Sucrose synthase 1, Sucrose-UDP glucosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.
Protein: PSA5_YEAST
Sequence: MFLTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAAESPEEADVEMS
What is the function of this protein?
The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-5, Macropain subunit PUP2, Multicatalytic endopeptidase complex subunit PUP2, Proteasome component PUP2, Proteinase YSCE subunit PUP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PETM_PROMA
Sequence: MASEIFGTAAIFWVLIPAGLLGGALLLKLQGE
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 7, Cytochrome b6-f complex subunit PetM, Cytochrome b6-f complex subunit VII.
What is the protein family that this protein belongs to?
Belongs to the PetM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: AX2R_HUMAN
Sequence: MEQHFLGCVKRAWDSAEVAPEPQPPPIVSSEDRGPWPLPLYPVLGEYSLDSCDLGLLSSPCWRLPGVYWQNGLSPGVQSTLEPSTAKPTEFSWPGTQKQQEAPVEEVGQAEEPDRLRLQQLPWSSPLHPWDRQQDTEVCDSGCLLERRHPPALQPWRHLPGFSDCLEWILRVGFAAFSVLWACCSRICGAKQP
What is the function of this protein?
May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.
What are the official names of this protein?
Annexin-2 receptor, Annexin II receptor, AXIIR.
Protein: RL30_RICM5
Sequence: MNNKINNIKITQVQSAIGRKYDQRLILVGLGLNKINKSVILANTNSIKGMVEKVKHLLKIENM
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: UVRC_EDWI9
Sequence: MSERFDAVAFLKTVTNQPGVYRMYDAGAEVIYVGKAKDLKKRLSSYFRCQLASRKTEALVRQIAQIDVTVTHTETEALLLEHNYIKRYQPRYNVLLRDDKSYPLIFLSADRHPRLAVHRGARRARGDYFGPFPNANAVRETLALLQKLFPIRQCEDSVYRNRSRPCLQYQIQRCLGPCVTGLVNDGEYARQVEYVRLFLSGKDSQVIDALVARMEEASRALRFEEAARLRDQIQAVRRVTERQFISGDHEDIDVIGVAFEAGMACIHVLFIRHGQVLGSRSYFPRVPAGTTLAEVLQTFVGQFYLQGSQIRTLPGEILIDFLLPDRKLLADSISELAGRRIPIQSQPRGDRARYLKLARTNAVTALNSKLSQQSTILQRLVQLEQVLQRADIQRMECFDISHTMGEETVASCVVFDRNGPLRSEYRRYNIKGITPGDDYAAMDQVLRRRYDKALNEEKIPDIIFIDGGKGQLGQAKQVFAELEVPWDTHRPLLLGIAKGSDRKAGLETLFFEAQGEGFSLPPDSPALHLIQHIRDESHNHAIAGHRKRRAKVRSTSALESIEGIGPKRRQLLLKYMGGMQPLRDASIDEIAKVPGISAALAEKIHYALKQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_SALHS
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKHGAESWMGFVGFLQNPVVVILNLITLAAALLHTKTWFELTPKAANIIVKDEKMGPEPIIKGLWVVTAVVTVVILYVALFW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YNEP_BACSU
Sequence: MHVSKKEIEVRYAETDQMGIVYHANYLVWMEVGRTALIKDLGFLYSDMEKKGVLSPVVDINISYKKPLHYGETAVVHTWIEDYNGFKTVYGYHIYNPAGELSIKATSSHICVDKESFKPIQFRKAFPDWHTAYEKAKK
What is the function of this protein?
Has acyl-CoA thioesterase activity.
What are the official names of this protein?
Putative acyl-CoA thioesterase YneP.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
Protein: SYP_CHLAA
Sequence: MPKEVITQRSVDYNQWYLDIVREADLAEVAEVVRGCIVVKAHGWAIWELMQRALDDRIKATGHANVQFPLLIPKSFIMKEAEHVEGFAPEVAEVTRAGGEELAEPYIIRPTSETIIGYFYSKWIRSYRDLPLLYNQWANVMRWEMRTRPFLRTAEFWWQEGHTAHATEAEAEEETLRILHDVYADFVEKEMAVPVIRGLKTEKEKFPGALRSYCIEAMMQDGRALQAGTSHNLGQNFARAFDITFTDQNNTIQYAWTTSWGVSTRLIGALIMTHSDDEGLVLPPRLAPIQVVVVPIYKNDEERSLVMAAVEQMTAAWKGRLRFKVDDRDNYSPGYKFNEWELKGVPVRIEVGPKDVAKETVALARRDIPGKAGKSFVPQAGLTERIEALLNEMQTALFQRALAFREAHTADVTSYDELKEQIERGFARAYWAGDTADEKRIQEETRATIRCIPLEQPGSVGRCVYTGRETDRQVIFARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX323_LYCSI
Sequence: MKFVLLFGVFLVTLFSYSSAEMLDDFDQADEDELLSLIEKEEARAKECIPRFYDCSHDRHSCCRSELFKDVCTCFYPKGGDNEVCTCQQPKHLKYMEKAADKAKKFGGKIKKWFG
What are the official names of this protein?
U3-lycotoxin-Ls1i, Toxin-like structure LSTX-B23.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SOX30_MACFA
Sequence: MERARPEPQPQQRPLRPAPPLLPVEGTTFWAAAVEPPPSPPTLSAAASATLASSCGEAVASGLPPAVRRLLQVKPEQVLLLPQPQARDEEAAASPAQARLLQFRPDLRLLPPPSASEGAPSRPELHPVQPRALHFKAKKQELGPGLDPSVGPRGGVETGPRASRVVKLEGPGPALAYFRGNEKGKLEAEEVMRDAMKGGDGKSPAAIREGVIKTEEPERLLEDCRLDAEPASNGLVHGSAEVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPIKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLPTPAVQRPSPVTLFQPSVSSAAQVAVQDPSLPLYPALPPQRFAGPSQTDTHQLHSEGTHTVKQPTPVSLESTNRISNSASTAHARFATSTIQPPKEYSSVSPCPRSAPIPQASPIPHPHVYQPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLGYYEDRYQKHEAIFSALNRDYSFRDYSSERTHSENSRSCENMNGTSFYNSHSHSGEEYLNPVPQLDIGALENVFTAPTSTPSSIQQVNVTDSDEEEEEKVLRDL
What is the function of this protein?
Acts as both a transcriptional activator and repressor (By similarity).  Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif (By similarity).  Binds to its own promoter and activates its own transcription (By similarity).  Required to activate the expression of postmeiotic genes involved in spermiogenesis (By similarity).  Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling (By similarity).  Also inhibits Wnt signaling by binding to the CTNNB1 protein, preventing interaction of CTNNB1 with TCF7L2/TCF4 (By similarity).
What are the official names of this protein?
Transcription factor SOX-30.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Enriched at the chromocenter.
Protein: ACP_PARUW
Sequence: MSIEQEVIDIVVEQLGVDRDDVNSEKSFVEDLNADSLDLTELIMTFEERFECEISQEDAEKLKTVNDVISYLEKRKS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGS_ASPOR
Sequence: MAAVKSCVEEEKIDCDLDFDKVIDVQLDDNHCAKLKAGYESLLSRGALTVTEADFTPNETAESEFFLSLLNSASTKREAKSYLARLKAQHPPKAQTEPTTGHSKGTVTQSLPSGVNLGSFYGASRSVYDSPVFRHDSTPLPPPSELPEERLHLALIKIRTPQLLDDTIINGVAKTLSQLSRLGMACCVVVDPGTAGNANTLRRVAAEQAERISIAVDAQPDSKSAHLDSVLSLSPMFPELPTVLSRKALLNPLRDGQIVVVAPIAYTEDVPKAVTISANDAILALTKELAGLAMRPDPDEDPWLTAQKIAKLQKEVSLDRVILLDPLGGIPSFRGPQTSHVFINMEQEFDDIKNELLHVQSSEACTATTPKGGNTFVEDPLERHLDNLQLSQNVLAMLPSASSGIITSPLEVSNSARTPQANPSDVSAVGTRRQRNPLIHNLLTDKPLLSSSLPMSRREAMNRRRGSINTPSSHTTFVKRGMPLTMIPNPRVEVWTAQNRPRLSLDDPSIDLPRLVQLIEDSFNRKLDVQDYLNRVNDRLAGLIIAGEYEGGAILTWELPPGVEDDGSPASEARMVPYLDKFAVLKRSQGAGGVADIVFNAMVRSCFPNGVCWRSRKDNPVNKWYFERSTGTWKLSDTNWTMFWTTPGLTENSQRFSDYEQVCRSIQPSWADDTGVVD
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MIAB_BURCM
Sequence: MTKKVYVKTFGCQMNEYDSDKMVDVLNAAEGLEKTDTPEDADIILFNTCSVREKAQEKVFSDLGRVRELKEAKPGLLIGVGGCVASQEGASIVSRAPYVDLVFGPQTLHRLPQMIDQRRASGRAQVDISFPEIEKFDHLPPARVEGPSAFVSIMEGCSKYCSYCVVPYTRGDEVSRPLDDVLTEVAGLADQGVREVTLLGQNVNAYRGALTAGSTEIADFATLIEYVADIPGIERIRYTTSHPKEFTQRLIDTYAKVPKLVSHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPDLSLSTDMIVGFPGETEEDFDKMMALVHEMSYDTSFSFIYSPRPGTPAANLHDDTPREVKLKRLQHLQATIEENVARISRSMVGKVERILVEGPSRKDPNELSGRTENNRVVNFPAPLASHPRLIGQMIDVKINHAYPHSLRGELLLVSDDASAATH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_FRATM
Sequence: MISNFILFALFIVTIALITKPLGSYIFRVFNNERTYLDWLAKPFQRVYLLVLGESSKKEQTAKAYFFSLVSFSVMAFIFVLVILLLQGILPLNTQEIKGMSFPQALNTAVSFITNTNWQSYSGETGVSYFAQMLALAVQNFVSAAVGLCVAIALIRSVARHETATIGNFWNDLGKGVFWILLPISIVIAIVYIFQGVPQNVMAYLHVHTLAGTEQIISQGPIASQEAIKSLGTNGGGFFNANSAHPYENPTVITNYIQMVSIFAIAAALTYTFGKWVGNTKQGWLIFGVMLVLFIISLVVMTISELHGLDFLHSKDIQDIYGQVGHLSNMEGKESRFGVFYSTLYNTVSTSASDGGVNSVLDSYSPLAGMMAMLNMAIGEVIFGGVGAGFYGFFMFLMLAVFIGSLMIGRAPSFLGKRIEANDMKWTMFALLISPCCVLVFTGLAAVIPSVHQTLTNSGAHGFSEILYAYISGANNNGSAFAGLSANTNYLNITIALSMLIGRFGVIFAVIMLAGSLVKKKRSLQMSEISSLDTTSFIFAILVFFTILLIGGLTIFPALGLGPILDQLNLNFL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.