PharMolix/UniProtQA huggingface dataset:
Protein: RS20_EHRRG
Sequence: MANHPSAKKMIKVIKKRTMINRMRKSRAHNYIKKFMAALAAGNKELMLENFKKAESNLHRCVNKKIIHRNTAARKISRLALKLKTFDLQQQEKAS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SEC23_CRYNJ
Sequence: MNFEDIEDKDGVRFSWNVWPSSRLEATRTVVPISALYTPLKEREDLPPVMYEPVTCKGSSCKAILNPYCQVDVRGKMWICPFCLQRNPFPPHYHQDLSPNNLPPELLPKFTTIEYTLSRPAQIPPIFLYVVDTCVDEDELKALKETLVVSLSLLPPNALVGLITYGTMAMVHELAYADCPKAYVFRGSKDYQPKQIADMLGLNPSNRPIQPVRPGQPMPAPAASKFLMPVQACEFQLTNILEQLQRDPWPVEQDKRPLRCTGVALSVAVSLLETAFPNTGARIMLFSGGPATDGPGMVVGPELREPIRSHHDIDRDSVKHFKRASKFYEALSKRASVNGHAIDIYAGCLDQVGLLEMKSLTNATNGVMTISDSFMTAIFKQSFLRTLGKDEQGYLKMGFNATYDVLTTKELKISGVIGHVISANKKSSCVGETEIGIGQTSAWKVCSLTPKSTLATYFEVVTPAGQALTPNQSGLIQFVTHYQHSSGQYRLRVTTVSRVFQEGGHPSIAASFDQEAAAVLMARIAVFKAEIDDSPDVLRWLDRMLIRLCQKFADYRKEDPTSFQLSPNFSIYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNDSDVNNSLIMIQPTLMSYGFDSEPHPVLLDSVSIRPDVILLLDTFFHILIFHGETIAQWRKANYQEQEDYANFKELLEAPIGDAQELLEDRMPIPRYVVCDQGGSQARFLLSKLNPSTTHMSGSNYGAGPAGGQAIFTDDVSLQVFMEHLKRLAVGASTS
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC23.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS19_LEVBA
Sequence: MGRSLKKGPFADAHLLKKIDAQKDSEKKTVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYVQEDMVGHKLGEFVPTRTFRGHGGDDKKTR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FMT_BIFLD
Sequence: MLKLVFAGTPDVAVPSLKAFAADPRFDVVGVITRPDAPTGRGRKLTPSPVKATALELGLPVIDLKPRSPEFMEALNNLHADIAAVIAYGNILPKNVLDAVPMGWYNLHFSNLPKWRGAAPAQRAIWAGDPTTGADVFKVGEGLDDGPIVASLTIELTGRETSGELLDRLAEEGAPMYVDALAAVGEGTATFTAQPAEGLEYAHKITVEDARISWTDEAEAIDRQVRACTPHPGAWTELFAEGPIADNDEPAAKPLTLHILAAQPADQSNPNTPAELQPGELKVGKKNVWVGTGSTPLELTQVKAQGKKAMRAADWARGARLSPAACVR
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DNLJ_KLEP3
Sequence: MEPIEQQLTELRTTLRHHEYLYHVMDAPEVPDAEYDRLMRELRELESQHPELITPDSPTQRVGAAPLTAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTDDLTYCCELKLDGLAVSILYENGVLMQAATRGDGTTGEDITSNVRTIRTIPLKLHGENIPARLEVRGEVFLPQAGFEKINEEARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPASHSARLQQFKAWGLPVSDRVTLCHTPEEVLTYYRKVEEDRPHLGFDIDGVVIKVDSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLKIGDKVVIRRAGDVIPQVVNVVLSERPADARDVVFPTHCPVCQSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRALDVDGMGDKIIDQLVEKEYVHTPADLFRLSAGKLTGLDRMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAALAAHFGTLEALEQASIEELQKVPDVGIVVATHTFNFFAEESNRDVIAQLLAEGVHWPAPVVVKAEEIDSPFAGKTVVLTGSLSQLSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMMRLLGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: KATG2_SHESM
Sequence: MKKTTIPTLSALTLAMSLAFGGAAIAQEQVTGNQFWWPEQLNLSPLRQNAVESNPYGSDYHYAEAFKSLDLDAVKKDIKALMTESQDWWPADYGHYGPFFIRMAWHSAGVYRIFDGRGGAAGGQQRFEPLNSWPDNVNLDKARRLLWPIKQKYGSKISWGDLMVFTGNVALESMGFKTFGFAGGRVDDWEAEQVNWGSEKAWLDSKRRNEKGELAKPMGATQMGLIYVNPEGPNGVPDPLASAKEIRDTFGRMAMNDEETVALIAGGHTFGKAHGAHDPSKCVGADPAASGVEAQGLGWKNKCGKGHSEDTVTSGLEGAWSSNPTKWTMEYLTWLYTFDWVQTKSPAGHIQWIPADGKAANLIPDAHIADKRHAPMMFTSDIALKEDPIYREITTRFLKNPQEFELAFAKAWFKLTHRDMGPKARYLGADVPAEMLIWQDPIPALDHLVIDNADIKALGNKILASGLTVPELVRTAWASASSFRGTDMRGGANGARIRLEPMMNWQANNPKELAKVLAKLEKVQKDFNGSLKGGKKVSLADVIVLGGSVAVEKAAKEAGVAVSVPFTPGRMDATQAQTDVSSFAVLEPTADGFRNYYSKDSSHSPAEMLIERANMLNLTVPEMTVLVGGLRALDANSAGVKHGVFTDKPGTLSNDFFVNLLDMSTKWSKSEKQEGIYEGQDRKSGKLKWTATPVDLVFGSHSELRAVSEVYGAQDGQDRFVQDFIKAWNKVMNADRFDI
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 2, CP 2, Peroxidase/catalase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: WECF_ECOSM
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPTLSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIATGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EXBB_AQUAE
Sequence: MMEEIKELIDYGIMGTLLFMSFVALAVGIERYLSIRSTKVENFKSKAQLEKELTKRLYIIATVASNAPYVGLLGTVLGILLTFYIIGEKGIVNTKEIMVGLALALKATALGLIVAIPSTILYNFLVRKVREKLLDWEAIHGECSSSHE
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.  Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
What are the official names of this protein?
Biopolymer transport protein ExbB.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMM_XYLF2
Sequence: MSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHWRRLIFARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGSTRSVDSAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTWVLICQHLRVTSIDNAALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIFNLKLPMKKRWDETRLCLERFETQAAVPLTLRAKQLYHDREEITVYASNDAR
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCRM_TETCF
Sequence: MPFGNTHNKWKLNYSAAEEFPDLSKHNNHMAKALTLDIYKKLRDKETPSGFTLDDIIQTGVDNPGHPFIMTVGCVAGDEECYEVFKDLFDPVIEDRHGGYKPTDKHKTDLNQENLKGGDDLDPNYVLSSRVRTGRSIKGIALPPHCSRGERRLVEKLCIDGLATLTGEFQGKYYPLSSMSDAEQQQLIDDHFLFDKPISPLLLASGMARDWPDGRGIWHNNDKTFLVWVNEEDHLRVISMQKGGNMKEVFRRFCVGLKKIEDIFVKAGRGFMWNEHLGYVLTCPSNLGTGLRGGVHVKIPHLCKHEKFSEVLKRTRLQKRGTGGVDTAAVGSIYDISNADRLGFSEVEQVQMVVDGVKLMVEMEKRLENGKSIDDLMPAQK
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
What are the official names of this protein?
Creatine kinase M-type, Creatine kinase M chain, M-CK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_DESVM
Sequence: MSGNNMLKIGIPKGSLEEATVNLFARSGWKIRKHHRNYFPEINDPELTARLCRVQEIPRYLEDGVLDVGLTGKDWLLETGADVVTVSDLVYSKVSNRPARWVLAVAGDSPYVRPEDLAGCTIATELLGVTRRYFEDAGIPVKVQYSWGATEAKVVEGLADAIVEVTETGTTIKAHGLRIIAEVLLTNTVLIAGKAAWADPWKRAKIEQIDLLLQGALRADSLVGLKMNVPAHNLDAVLDQLPSLNSPTVAGLRDSTWYAVEIVVENDLVRDLIPRLRAAGAEGIIEYSLNKVI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATRMA_PYRFU
Sequence: MRGIIKRLNDDGFGILYNKILVPFSAPGDEVEVLKTEKQKRAKIATEWRLLRSSPIRVGARCKVFGKCGGCILQHINYNSQLEFKKEKLRKILGREVEIIPSPRIFGHRNRIDLAVTVNAIGFREKGKWWSVVDVEECPVFGKTSKKAIERLREYIEEEKVSTWKIREDSGFLRYMVLREGKFTGEIMVNFVTKEGELPDPTSYFDFADSIYWSINRSKSDVSYGDIEKYWGKEFIMEELDGVKYLIHPNSFFQTNSYQAVNLVKTVEKFVEGEKVVDMYSGVGTFGVYLAKKGMKVVGFDSNAFAIEMANKNAEINNVEAEFFVASDREVDIKGFDTVIVDPPRAGLHPKLVKRLNDHGPETIVYVSCNPKTFKVNIEQLNNYIIEELIALDMFPHTPHIELVGKLRRLV
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in tRNA.
What are the official names of this protein?
tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: RLME_ECOLC
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_AJECG
Sequence: MIRQCVSHRGIPCYRLAVRRVELTEPFHHPSPRPLGRKNWSTSDEAKSKRAAMRKGGAPPPEHEDWELTVGIEIHAQLDTDAKLFSRASAALDDVPNSNIALFDIALPGSQPLFQPSTLIPAIRAAIALNCDIQRIRGQRIYELTHRLIEPYAKNGSIWLGAHDGIAKEDGEGVQIGIKQIQMEQDTAKSQELPSSTYLLDFNRVSRPLIEIITLPQIHSATTAAACVRKIQAILQSVGAVTTGMEMGGLRADVNVSVRKRSEAAGDHQYDGVAGLGQRTEIKNLSSFKAVEYAIIAERDRQIAVLKAGGTIQGETRGWTLGSTETRKLRGKEGEVDYRYMPDPDLGPVIIGDDVISDLRRNIPVLPDELLQMLVQDPKYGLSTVDAKTLIELDDGQRLEYYQDAVEILITLQPDLSADFSAGKVVGNWVLHELGGLLTKSSAHWDSQRVPAQSLAEIINLLSRKNITSSSAKSLLAMAFDGDKRSISQIVEDKNLLFQSLSRHEYIALAEEVMRQNPKMVSEIREKGQLGKMGWFVGQIKRIGDPNRVEAQKAEEILRELILK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IDTC_CLAPA
Sequence: MTTLAWFAGRSMVLDLAALTSAFTVGYLLKSTSTPTSTPTSTDKAGTPPGSTIHHYGYPQGSVTKPNNSKTEKENGSPKDSKGNVPDCPYKYLVGLYGHHHFAGFVEALQPTLKDEDPEKYTLVLDIMDAVHLCLILVDDICDDSPKRKNQTTAHLLFGSCETANRAYLVLTKVINRAMRTRPVLGAELVRALELILEGQDLSLVWRRDGLAAFDAEEGGDKVSVYKKMAQLKTGTLFVLLGRLLNDGGAQLDDVLLRLGWYSQLQNDCKNIYSGEYANNKGAIAEDLRNGEMSFPVVVALGDQTTSSQIRKAFGSHSDGDIFDALDALQSSCIKNKCSQALQEAGRGLENLLAIWGRREHMDSLGS
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of paspalitrems, indole-diterpene (IDT) mycotoxins that are potent tremorgens in mammals (PubMed:23468653, PubMed:29457197, PubMed:32077051).  The geranylgeranyl diphosphate (GGPP) synthase idtG is proposed to catalyze the first step in IDT biosynthesis via catalysis of a series of iterative condensations of isopentenyl diphosphate (IPP) with dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and farnesyl diphosphate (FPP), to form GGPP (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyltransferase idtC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation of the two terminal alkenes of the geranylgeranyl moiety by the FAD-dependent monooxygenase idtM, and cyclization by the terpene cyclase idtB then leads to the production of paspaline (Probable).  The cytochrome P450 monooxygenase idtP then catalyzes oxidative elimination of the pendant methyl group at C-12 of paspaline and generates the C-10 ketone to yield 13-desoxypaxilline (PubMed:32077051).  The cytochrome P450 monooxygenase idtQ may catalyze the C-13 oxidation of 13-desoxypaxilline to afford paxilline (Probable).  Considering that both paspalicine and paxilline were detected in C. paspali, idtQ also catalyzes the formation of paspalinine from 13-desoxypaxilline via paspalicine as an intermediate (Probable).  Finally, the alpha-prenyltransferase idtF prenylates paspalinine at the C-20 or the C-21 positions to yield paspalitrems A and C, respectively (PubMed:32077051).  The hydroxylation of paspalitrem A at C-32 by a still unknown oxidase affords paspalitrem B (Probable).
What are the official names of this protein?
Prenyltransferase idtC, Indole-diterpene biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: ALFL7_ORYSJ
Sequence: MDEGGGAGAAAAAAGNAAGAAVHHNARSAEDVFRDFRARRAGIVKALTTDVEKFYRQCDPEKENLCLYGLPNETWDVTLPAEEVPPELPEPALGINFARDGMIEKDWLSLVAVHSDAWLLSVAFYFGARFGFDKEARRRLFTMINGLPTVYEVVTGIAKKQTKVSNGSSKSNKSNPKPSKQSNSNSKPAKPPQPKDEEDSGPEGTEDEDQAYMCGACGETYANGEFWICCDVCEKWFHGKCVRITPAKAEHIKQYKCPGCSSKRSRE
What is the function of this protein?
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
What are the official names of this protein?
PHD finger protein ALFIN-LIKE 7.
What is the protein family that this protein belongs to?
Belongs to the Alfin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Z354C_HUMAN
Sequence: MAVDLLSAQEPVTFRDVAVFFSQDEWLHLDSAQRALYREVMLENYSSLVSLGIPFSMPKLIHQLQQGEDPCMVEREVPSDTRLGFKTWLETEALPHRQDIFIEETSQGMVKKESIKDGHWDINFEEAVEFESEIEEEQEKKPLRQMIDSHEKTISEDGNHTSLELGKSLFTNTALVTQQSVPIERIPNMYYTFGKDFKQNFDLMKCFQIYPGGKPHICNECGKSFKQNLHLIEHQRIHTGEKPYKCNECEKTFSHRSSLLSHQRIHTGEKPYKCNECEKAFSNSSTLIKHLRVHTGEKPYRCRECGKAFSQCSTLTVHQRIHTGEKLYKCGECEKAFNCRAKLHRHQRIHTGEKPYKCSECGKGYSQFTSLAEHQRFHTGEQLYTCLECGRTFTRIVTLIEHQRIHTGQKPYQCNECEKAFNQYSSFNEHRKIHTGEKLYTCEECGKAFGCKSNLYRHQRIHTGEKPYQCNQCGKAFSQYSFLTEHERIHTGEKLYKCMECGKAYSYRSNLCRHKKVHTKEKLYKWKEYGKPFICSSSLTQYQRFFKGDKAYEV
What is the function of this protein?
May function as a transcription repressor.  Binds to 5'-CCACA-3' core sequence.  Suppresses osteogenic effects of RUNX2.  May be involved in osteoblastic differentiation (By similarity).  Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).
What are the official names of this protein?
Zinc finger protein 354C, Kidney, ischemia, and developmentally-regulated protein 3, hKID3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMS_SYNY3
Sequence: MCGIVGYIGTQTAVNILIEGLERLEYRGYDSAGIATVTEGKIESVRAKGKLFNLKEKLENHSNFSRLGIGHTRWATHGKPEEHNAHPHLDNQQRIAVVQNGIIENYQTLRDQLKEKGYQFYSETDTEVIPILIADILKDLPSDDPDEALLEAIGKAVHQLEGAFAIAVLDAHCPEQLIVARQQAPLILGFGQGEFFCASDVTALVHHTTTVLSLENGEIARLTPLGVEVYDFNLKRVRKLPRTLDWSATTVEKQGFRHFMLKEIYEQPAVVRTCLATYLNEQWRAADHPSHSPVFLGLDPQLTKNLQHIQVLACGTSWHAGLVGKYLLEQLAGIPTTVHYASEFRYAAPPLTPHTLTIGVTQSGETADTLAALEMEKQRRLTLEDDYKPLILGITNRPESTLATMVNEIINTHAGIEIGVAATKTFVAQVLAFYFLALDIAFQRHSLSLEAIEHIMVGLRQLPAQIETILEQQGSAIEALAHEFAETQDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDAKVPVVAIAMPGSVHDKVISNAQEAKARDARLIGVTPMDDSQARSVFDDLLLVPHVEEMLSPIVAVIPLQLLSYHIAARRGLDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTP3_ENCCU
Sequence: MLLFLLCLYSMVARGDLGSRSSSHAVHHHHSKEGKNASGMDYGNRSTRNARVKVRLHNHNDDSQDGHHHHKVHRSHGGSIKPHNQKHAKLIRNMIGTHENDPENLTHEEKDLANMAAHGNLDALDMLYRNGSITPDVAESVGGSIPGGITEPVVIQPAESSPMEVNEEARVVDTMSPPDYSDPTGVYVSNGVATGRTNEEQAEINVLNRNENPIDDGIAEEAYSSLLSVGHSLPVAKAVADEIKDANVRKMLRTKRAYDISQPPVNPVYIPQAELARATNSKDVVSDTDRQMFMKKVFEEYIRQGAPVERANFEAGQAGFLIDEYNENLASGLSPDAAYEKAMSLVDLNYQHATRAAAIAGGGQVAAQNAADRSLIEETSANEMVKTPSGLRPEVLKKKEEAINSKKLDRAQDLSSYLTKLHIVEPVNRAHQKLSQAAALKDAASMEGLDNPVVQEKILTDVAASSAEDLAKAHENLENVKTQLKPGGRKTNALNFLSKVLTEKAIKDVNQRNEEMQKEAVKAQKEANENSAVKSAEEHLAKAAEQQIINNEGKSVFSKVLESTGDISEAAKAREEAERAMAETLRHQREARKAEVMKMLGPMGMNSSVKEAVEHMATAHAGLNVVGSDLNELNKKYEEEVAHQSNIEELLRETATSNLEVKEVIPPTTSRVGISEGKIKLPLKGFSNEEPKTEEETIVQSRQRNRRNQVRNKVIGTPVESGLNVVEMEDGYMHISEAAKALKINKGKVFYPESAKGIMEKQKLDTSLLEHKFNTGERAGLDKGVGYYEADASGFTLPLPSPLNPVPTSTMTNEEKSLNIGHAFELEIEDGELIQTPWIEFVKDMRPMVNGRMAHEAEVAAASEMKSRVEEEKKAKNLEGITTEVYTNPDGSKFVEVSSPYGVPEIMTMDQAVESLKSVGSSSVGAVSEEAKKQTPEVPLDMAVTNSVKGSEESFVSSVLSTIQKIGNGKALAKRNAFNGKVDGEKAAIVDEYNKELINEHLSPSSTVEARVRNSIISKAESYARSMGISTQSFLNMISQLPDSSIKEMISYNEAPPSARKDVAETHFYNQIASILPDSKTANTGSVTEMIFNNISTVTHEPNTVGGEILEQMTVPNLKTIEQVETKKTPTGTTQVSVSVPNDPGKIQVLGEVKFKGNPTTTPSSGRRPASNQAVAPANVVPGPMVPSSGRNPLKPGARLPANNGPVSNAPAARIPAGQPDHTMRGFSHSFPNNPQAPGIGATPSPAVGYSGKIAR
What is the function of this protein?
Involved in the sporoblast-to-spore polar tube biogenesis.  Plays a role in the control of the polar tube extrusion as part of a specific response to ionic stimuli.
What are the official names of this protein?
Polar tube protein 3.
What are the subcellular locations of this protein?
Spore polar tube.
Protein: PVK3_MANRE
Sequence: GKTKGVTSGLIAFPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, Manre-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURE_ALCBS
Sequence: MMTLQQLLPNTTLPATAAGVVLSGLQLDSRKVMPGDAFLAVQGVASDGRQFVSQAIAAGAVAVLAEAETFSVQQEQAVPRVNFPGLSRSVGELAARWYGEPGSAMNVVGVTGTNGKTSITWFLRDALNALGHRCALVGTLGLGLKDNEQITGHTTPDPITLQAGLARVLEAGADTVAMEVSSHALDQHRLGPTPVSVAVFSNLSRDHLDYHGDMEAYLAAKSVLFTRDGVKLAVINCDDPVAYSLVGCLADGVRCVTFGDQTGATVRCASVAFTAEGTNAELNVGGESFSVTLPLFGRFNLSNLMAVAGILHGQGVSTDSLAGALAAITPVPGRMEPVQQAGCPTVIVDYAHTPDGLEKALQACRAHFAGRLFCIIGCGGDRDTGKRPQMAAVAERGADHVVFTSDNPRSEDPQKIIDEMCAGLTDTGSVQIIVERDRAVMDTVQAASDGDVILLAGKGHEDYQEVNGVRYPSDDRDLAHKAFNARGGAQ
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNJ2_CANLF
Sequence: MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKESKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPVAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDLDLHNQASVPLEPRPLRRESEI
What is the function of this protein?
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Blocked by external barium or cesium (By similarity).
What are the official names of this protein?
Inward rectifier potassium channel 2, Cardiac inward rectifier potassium channel, Inward rectifier K(+) channel Kir2.1, IRK-1, Potassium channel, inwardly rectifying subfamily J member 2.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Membrane; Lipid-anchor.