PharMolix/UniProtQA huggingface dataset:
Protein: ISPE_STAAW
Sequence: MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGASLEELALLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKPPSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGADGALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: FAPR_BACP2
Sequence: MKLNKKERQKLLQQTISSTPFITDEELATKFGVSIQTVRLDRLELSIPELRERIKHVAEKTLEDEVKSLPLDEVIGEMIDVELDDQAISILEVRKEHVFSRNQIARGHHLFAQANSLAVAVIDDELALTAKANIKFTRQVKQGERVVSKAKVASHDKEKGRTVVEVNSYVGEEVVFSGDFVMYRSKQK
What is the function of this protein?
Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
What are the official names of this protein?
Transcription factor FapR, Fatty acid and phospholipid biosynthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the FapR family.
Protein: KIN12_ARATH
Sequence: MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL
What is the function of this protein?
Catalytic subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, a central regulator of cellular energy homeostasis, which, in response to seemingly unrelated darkness, sugar and stress conditions, activates energy-producing pathways and inhibits energy-consuming processes.  May also be involved in the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase and in assimilation of nitrogen by phosphorylating nitrate reductase.
What are the official names of this protein?
SNF1-related protein kinase catalytic subunit alpha KIN12, AKIN12, AKIN alpha-3, AKINalpha3, SNF1-related kinase 1.3, SnRK1.3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: FAD3E_BRANA
Sequence: MVVAMDQRSNVNGDSGARKEEGFDPSAQPPFKIGDIRAAIPKHCWVKSPLRSMSYVTRDIFAVAALAMAAVYFDSWFLWPLYWVAQGTLFWAIFVLGHDCGHGSFSDIPLLNSVVGHILHSFILVPYHGWRISHRTHHQNHGHVENDESWVPLPEKLYKNLPHSTRMLRYTVPLPMLAYPIYLWYRSPGKEGSHFNPYSSLFAPSERKLIATSTTCWSIMLATLVYLSFLVDPVTVLKVYGVPYIIFVMWLDAVTYLHHHGHDEKLPWYRGKEWSYLRGGLTTIDRDYGIFNNIHHDIGTHVIHHLFPQIPHYHLVDATRAAKHVLGRYYREPKTSGAIPIHLVESLVASIKKDHYVSDTGDIVFYETDPDLYVYASDKSKIN
What is the function of this protein?
ER (microsomal) omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes.  It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine and, possibly, other phospholipids.
What are the official names of this protein?
Acyl-lipid omega-3 desaturase (cytochrome b5), endoplasmic reticulum, Omega-3 fatty acid desaturase 3, endoplasmic reticulum.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YEW7_SCHPO
Sequence: MSEQSSPYLTLAPADYEGEDVSNEKEKNSVIPDVIDYYNKGRQYYQSFVVYKATANTIFQFSYLLYIYIDLTKADQTEVLQFLKTYVEDESFVGDDFVMPKYTLVLPYRVYRDHVKKHGDIITPK
What are the official names of this protein?
Uncharacterized protein C3G6.07.
Protein: PP248_ARATH
Sequence: MLTKLRISKLVSYTLPRRIFQRRFLVTNNTAEESPIVAAESPELPSWIKDFLSNKPSSSSSSVSKDDEDFVIPSLANWVESQKFSRQQVSEGNVVKKPVEDIDKVCDFLNKKDTSHEDVVKELSKCDVVVTESLVLQVLRRFSNGWNQAYGFFIWANSQTGYVHSGHTYNAMVDVLGKCRNFDLMWELVNEMNKNEESKLVTLDTMSKVMRRLAKSGKYNKAVDAFLEMEKSYGVKTDTIAMNSLMDALVKENSIEHAHEVFLKLFDTIKPDARTFNILIHGFCKARKFDDARAMMDLMKVTEFTPDVVTYTSFVEAYCKEGDFRRVNEMLEEMRENGCNPNVVTYTIVMHSLGKSKQVAEALGVYEKMKEDGCVPDAKFYSSLIHILSKTGRFKDAAEIFEDMTNQGVRRDVLVYNTMISAALHHSRDEMALRLLKRMEDEEGESCSPNVETYAPLLKMCCHKKKMKLLGILLHHMVKNDVSIDVSTYILLIRGLCMSGKVEEACLFFEEAVRKGMVPRDSTCKMLVDELEKKNMAEAKLKIQSLVQSKTMIDSHSPLSVS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g22670, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS18_VIBCM
Sequence: MARFFRRRKFCRFTAEGVQEIDYKDVATLKNYITEAGKIVPSRITGTSAKYQRQLARAIKRARYLALLPYTDKHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: NANR_ECOL6
Sequence: MSPMNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.
Protein: ASSY_VIBVU
Sequence: MSKLNVNKVVVAYSGGLDTSVIIPWLKENYDCEVVAFVADVGQGEEELVGIEEKAKASGASECYVVDLKEELVADYIYPTLKTGAYYEGKYLLGTSMARPVIAKAQVEIARKVGADALCHGCTGKGNDQVRFEGAFAALAPDLKVIAPWREWDLVSREQCLDYLAERNIPCAASLTKIYSRDANAWHISTEGGVLESTWNAPNEDCWVWTVDPEQAPNEAEYVTLQVEKGEVVAVDGEQMTPYNALVYLNEKGAKHGVGRIDIVENRLVGMKSRGCYETPGGTIMMEALRAVEQLVLDKTSFEFREELGLKASHLVYDGRWFTPLRKSIMAAADELAQDVNGEVVVKLYKGMATVTQKRSENSLYSEAFATFGEDEVYDQSHAGGFIRLYSLSSRIRALNSQK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAS1_CANLF
Sequence: MRGARLMGALLALAGLLQGALALRMAAFNIRTFGETKMSNATLSKYIVQILSRYDVAVVQEVRDSHLTAVGKLLDTLNQDDPNAYHYVVSEPLGRSSYKERYLFLFRPDRVSVLDSYQYDDGCEPCGNDTFSREPAIVRFHSPLTEVKEFAVVPLHAAPLDAVAEIDALYDVYLDVQHKWDLEDIVLMGDFNAGCSYVAASQWSSIRLRTNPAFQWLIPDTADTTSTSTHCAYDRIVVAGSQLQHAVVPESAAPFNFQVAYGLSSQLAQAISDHYPVEVTLKRA
What is the function of this protein?
Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (PubMed:14688237).  Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity).  Among other functions, seems to be involved in cell death by apoptosis (PubMed:14688237).  Binds specifically to G-actin and blocks actin polymerization (PubMed:14688237).  Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity).  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity).  Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation (By similarity).
What are the official names of this protein?
Deoxyribonuclease-1, Deoxyribonuclease I, DNase I.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Secreted. Zymogen granule. Nucleus envelope. Note=Secretory protein, stored in zymogen granules and found in the nuclear envelope.
Protein: CO5_PIG
Sequence: MLQKKIEEEAAKYKYAMLKKCCYDGAYRNDDETCEERAARIKIGPKCVKAFKDCCYIANQVRAEQSHKNIQLGR
What is the function of this protein?
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process.  Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes.  C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
What are the official names of this protein?
Complement C5a anaphylatoxin.
What are the subcellular locations of this protein?
Secreted.
Protein: NCAP_I07A0
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGRMIGGIGRFYIQMCTELKLNDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRVDGKWVRELVLYDKEEIRRIWRQANNGDDATAGLTHIMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVLELIRMIKRGINDRNFWRGENGRKTRIAYERMCNILKGKFQTAAQKAMMDQVRESRNPGNAEIEDLTFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEKEGYSLVGVDPFKLLQTSQVYSLIRPNENPAHKSQLVWMACNSAAFEDLRVSSFIRGTRVLPRGKLSTRGVQIASNENMDAIVSSTLELRSRYWAIRTRSGGNTNQQRASAGQISTQPTFSVQRNLPFDKATIMAAFTGNTEGRTSDMRAEIIKMMESARPEEVSFQGRGVFELSDERATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: INO80_SCLS1
Sequence: MSTSSSNIPYDVGSPRQQSQTEIRSILNPSTTSTGAHPSFNQYHPPTAAPPLIPSHIPLQSTTPSTLGLSLGTPLYQSERDIGYPRDQKPTSNYYDPTSDSSERRPATAESKWSDREAKTSQRRDSYPYQQNQPPAPSTDGPMNLYNGGYKSPVNSHFPPGSPISHAHPQGRVPPLVTQSPRMPAMESPISRHNGLGGGPELQDKPVIKQEPVPASTPSRPVDPMAFSSILSSAAPEPTPKPQPTPTPIVSKPRKASRQPIPTLKPEPSSAPSSRQSSVAPAPQPPTSRVPAKRKANGETKPTPKPKPFTKDQERDIVILMSKLDGEPEDSDVEFAEEKRLYQTRSLKRKLEVEKIETSKTKQRRTDFTNKMAKRLEKHAKAGEERYREVEGDAAISKVQADEIQTEKERKKDMQRKRRREKTVQNNMEQKEIALAKAQAAQDDQERHKFLRDAQRAEKKAQQTKQILARGDKGPEIRAVSPMEPNMQGGSMSTFTAVDPDSTKKPKRGGARPRKSKEQKQAEKDSAAAAQEAIDKGESPALMPIRDAAEFKDMKPLPSKEGVTKIKLKFKAPAEPVEVKEESPSAPVDQHNTKMYHVVYDQIWKDLARKEVPKVFKLAVDSYSIRASNLKKTAILASKEAKRWQLRTNKGTKDLQARAKRVMREMMSFWKRNEREERDTRRAAEKQEIENAKKAEADREANRQKRKLNFLISQTELYSHFIGKKIKTDEVERSTDHPDVAVPDKADHAKPDHGDLPEGTAPAKVTNFEDLDFDAEDESVLKAAAMANAQNAIQEAQNKARAFNKKDDAPAMDDEGEMNFQNPAGMGDVDIEQPKMLQAQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAEKHGIWGPFLVVAPASTLHNWQQEITKFVPRLKVLPYWGTAADRKVLRKFWDRKHITYTEDAPFHVLVTSYQLVVSDVAYFQKMKWQYMILDEAQAIKSSQSSRWKSLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLKRLHMILKPFMLRRVKKHVQKELGDKIEEDIFCDLTYRQRAYYSNLRNQISIMDLIEKATIGDDNDTGTLMNLVMQFRKVCNHPDLFERAETTSPLSFSYFAEAGSFLREGSNVTVAYSARNMIEYSLPRLIWREGGRLDLPGHDNEHAGVKAKCLESLFNVWKPENIVDSAKEDGAFSWLRFTNTSVQELSTASRKDVFARAVDLVKRPQTLGRLNIVYDEEEDKNYTPVHSMLQIVNRKDRKPLAEVTNEGYLNKLFNVAKDVWGQSGMSRMEQCGRPSATAPPIEVTCSSRGAVIERQKILFNVPMRRALFGPSPVEEKALITSKVSPLFYPPKPMLPLPTSEKQRFTNIKVPSMRRFVTDSGKLAKLDSLLTKLKEGGHRVLLYFQMTRMIDLMEEYLTYRNYKYLRLDGSTKLEDRRDTVHDFQTRPEIFIFLLSTRAGGLGINLTSADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRMITRGTIEERIRKRALQKEEVQKVVMTGGAGGGVDFNTRSKENRTKDIAMWLVDDEEAAEIERKEAEQLRYEAENPTASKKGKGKGKKGKEGGGGSLEDLYHEGEGHFDDGSNRPSGTATPIAVDASKKKGSSSRKSGGGGRSKKAKTAKERLAMADGDVDMA
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMT82_ALTAL
Sequence: MAAYLFTCSILQTLSEAGKIEIAEDKLLHYLGELPGTPNGPVQLLENICTILEGQGRATHGNVIRHVLNIVVTEQELGGLGISGKSWEEVDEHTLHEIKFLTDAWLTAAESRAAARHLPQPLKQQDTRRLPMNLAEKILAHHAFSVPRRERVVAGDLLRVSIDWVIASELSWVGMKHSVTSLDMKPSAWRNDRFWLSGDHTVDPRTYHDKRVQALIKGLESAKRDLKMTENQGSNYTIMHTEFVRERAEPGMLVLGSDSHTCSAGAVSALAIGLGAGDVMAGLATGETWFKVPECIRINFTGQPAWYIGGKDVILSVLKQLKRNTYAAERIVEFGGAGAKLLSCDARFAISNMCTVRDPNDRPELKPTADDRSTSRNLVLLQAFLFPTVSLNRLSIAAGARYEGASYASTFEIDLGEVEPFIAIYPSPDQVCPVAERTGMRFDGCFIGACTTTEEDLVLAALVLEAGLKRGLTLEKGKRIVVPGSLPIVKNLRALGLLDIYKACGYEQPAPGCSLCLGIGADVAEAGSQWLSSQNRNFQNRMGRGAVGHICSAATVAASSFNMTLTDPCDLLNDVSETTFKEYLARCKVARGGSESKLAGGKQANNVQYIEPCLLGENARSAEGEVPALEAAAVSLDDARLGSINSRIYKLDDYVDTDALPQIIPAPACVGSPTDEMLGSHCFELTNPDFRDYVRSGHRVIVGGRAFGCGSSREEAPRALKGLGVQCVIARSFAFIFGRNMPNIGMLAIVLTDEAFYKAAQQGENIEVDVEGRVVHVAGQTFPFSLDDMELQLIRNRGLAASYQKLGSKVFAALCQKPAPLPISALADATLAQGGSIGRQMDW
What is the function of this protein?
Aconitase; part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (By similarity).  AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), dehydroalanine, L-alanine which are common for all 3 AM-toxins I to III.  The fourth precursor is L-alpha-amino-methoxyphenyl-valeric acid (L-Amv) for AM-toxin I, L-alpha-amino-phenyl-valeric acid (L-Apv) for AM-toxin II, and L-alpha-amino-hydroxyphenyl-valeric acid (L-Ahv) for AM-toxin III (Probable).  AM-toxins have two target sites for affecting susceptible apple cells; they cause invagination of the plasma membrane and electrolyte loss and chloroplast disorganization (PubMed:22846083).  The non-ribosomal peptide synthetase AMT1 contains 4 catalytic modules and is responsible for activation of each residue in AM-toxin (PubMed:10875335).  The aldo-keto reductase AMT2 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV), one of the precursor residues incorporated by AMT1 during AM-toxin biosynthesis, by reduction of its ketone to an alcohol (PubMed:15066029).  The cytochrome P450 monooxygenase AMT3 and the thioesterase AMT4 are also important for AM-toxin production, but their exact function within the AM-toxin biosynthesis are not known yet (PubMed:17990954).  Up to 21 proteins (including AMT1 to AMT4) are predicted to be involved in AM-toxin biosynthesis since their expression ishighly up-regulated in AM-toxin-producing cultures (PubMed:17990954).
What are the official names of this protein?
Aconitase AMT8-2, AM-toxin biosynthesis protein 8-2.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: UBIA_XYLFM
Sequence: MAYERFTSAITLLLHWRNRLDPYWKLARGDRPVGFLLLLWPTWWALWLAADGVPPWWTLCVFTTGIWLTRSAGCVINDYTDRWLDPHVERTCTRPLVTGTVSPRNALLMFATLMLIAFGLVLTMNQLTVLLSVAGLFLAMTYPYLKRYTHLPQVYLGLAFGWGIPMAFAAIQGKVPTLAWLLYIANILWTTAYDTWYAMVDRDDDIKMGAKSIAILFAELDLVVQGVLYTLMLLTLCLVGLRATLSHTYWISLISAVALIGYQFIIARRREPTACFRAFMHNNWVGMTIFAGIALATTH
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HOXA_CUPNH
Sequence: MSDKQATVLVVDDETRSQDALRRTLDEEFRVLTVSSADEARALLLRQPVSVILCDQRMPGLTGVEFLKEVRERWPEIVRIVISGYTDSEDIIAGVNEAGIYQYILKPWVPDHLIDTVRQAVEAQGLQGDMHRLDLELRTSTPVLRQRSSQKLASAQSAFNFERIVRAPGSPLDAVCEVAARVARYDLPVMVLGESGTGKELLARAIHYASPRAARAFVSENCAAVPDNLLESELFGHKRGAFTGAYEDHAGLFQRANGGTIFLDEIGDTSPAFQVKLLRVLQEGEVRPVGSPRWIPVDVRVIAATHCNLESDVHAGRFREDLYYRIAGVTISMPPLRERSGDLQPIAAKLLEQVAQELARPGLYFGGDALAAMMAYPWPGNIRELRNEIYRAVALSSGEEIRAQLFSRKVLHGQPGTVKRGPHVQTFPQSGTLQERLDAIEAVVLKEALLRHRWNKTHAAKELGLSRVGLRQKLLRFGLEEK
What is the function of this protein?
Probable member of the two-component regulatory system involved in the regulation of the hydrogenase activity.  HoxA is probably phosphorylated by a sensory component (which could be HoxX) and then acts in conjunction with sigma-54 as a transcriptional activator.
What are the official names of this protein?
Hydrogenase transcriptional regulatory protein HoxA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETD_SOLTU
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPPDPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LOLD_RHIME
Sequence: MNARVALQLSGIERHYGEGDTFLPILKGADLTLRSGETVALVAPSGTGKSTLLHIAGLLEHPDEGEVLVNGTSCNGLSDDRRTAIRRNEIGFVYQFHHLLPEFSALENIMMPQLIAGLPKAEAAERASALLDYMRIGHRGSHRPTELSGGEQQRVAIARAVANAPLILLADEPTGNLDPETAGYVFEALEALARQSGLAALIATHNHELASLMDRRVTIEDGKVVELK
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MNME_BRUSU
Sequence: MSEIGSYHDTIFALSSGRLPSGVAVIRISGPKTRFVYETICQAIPEPRHAALLTFRSRNGDAIDRGLTLFFPAPHSFTGEDCAEFHLHGGKAVVEKMLAVLGELPGCRIAEAGEFTRRAFANGKMDLTIAEGLADLIAAETEGQRRLAMQVASGNQRKLYSEWRQRLINARAFIEAELDFADESDVPGSVSMQVWQQLSALKHEIEHHIASGKRAAMLRDGLHVVIVGAPNAGKSSLLNFLAGRDVAIISKEAGTTRDLLEVKLDLGGIPVYVTDTAGLRETDSVVEKIGIERARARMAEADLVLSLEDMSGPVSVTVEKIEAETWLIGTKADLGGSASGLWKYHISTMTGSGLEQLLDALQAFAEAKIGQIEDAVPTRQRHINLLRATIEEIEKAIEGDDLPLELRAENMRLASQFLGRITGDVDVEEILDVIFSQFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFIP2_MOUSE
Sequence: RRSASDAELSAGAEGATGSEAAPPGDLGGRTRGGGRGSAAAAATTSTREAEGAERRGDTPARKPDPEAGRMDHHQLGTGRYQVLHNEEDNSESSAVEQPSTSSLAAPTVEAAASAPALDPDSPPPYSSITVEAPTTSDTDVYSEFYPVPPPYSVATSLPTYDEAEKAKAAALAAAAADAPQRNQEEDCTPRDDFSDVEQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
What is the function of this protein?
Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets.  As a result, may control many cellular processes.  Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes.  Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation (By similarity).  May modulate EGFR signaling (By similarity).  Together with NDFIP1, limits the cytokine signaling and expansion of effector Th2 T-cells by promoting degradation of JAK1, probably by ITCH- and NEDD4L-mediated ubiquitination (PubMed:27088444).
What are the official names of this protein?
NEDD4 family-interacting protein 2, NEDD4 WW domain-binding protein 5A.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane. Endosome, multivesicular body membrane; Multi-pass membrane protein.
Protein: RECR_PELPB
Sequence: MRYTSAALESLIDEFAKLPGVGRKTAQRLAMYILREPRAEAERLAEALLEAKDNVIRCSVCQNITDVGVDPCALCTSKARDRSVICVVESPVDMLAFEKTGHYKGLYHVLHGVISPLDGIGPDDIKVRELLLRFTMPQSPAVREVVLALNPTIEGETTALYLSKLLKPLGIHVTKIARGIPVGAELEFIDEATLSRAMEGRTVV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ERB1_ASPFC
Sequence: MNTSKASKKRKAVTRDVEEEAGVFSGDELNTGNLDGALSDNAHDLSSDEDESDSEVELIDDFSDEEDEEEEDVLDSDEIPSDGEDSAKKKSNAAPGELGAVIDDDDDDDDDESPSEEEQLNYRIEKDANGNDRFVYDEINPDDNSDYSDVDENANTIGNIPLSFYDQYPHIGYDINGKKIMRPAKGEALDALLDSIEIPKGWTGLTDPSTGKPLELSQEELELLRKVQMNEIPEDGYNPYEPIVEWFTSQQEIMPLSAAPEPKRRFVPSKHEAKRVMKIVKAIREGRILPFKPPTEEDEEDDTIVKYDLWADEAERKDHPMHIPAPKLPPPGYEESYHPPPEYLPSRKERKTWEEADPEDRDREFLPNDFGSLRRVPGYENFVKEKFERCLDLYLAPRVRRSKLNIDPESLLPKLPSPEELKPFPTACATVFRGHKGRVRTLAVDPSGLWLASGGDDGTVRVWELLTGRQLWSVKLSEEDPVNVVRWRPGKDALILAAAAGDDIFLAVPPIVDPAMEKASLDILDAGWGYAASVPPPTPAEANKKNNPPKWMRPSSSLADSGVCAVIPLRYVAKSLSWHRRGDYFVTVCPGSSTPASVAIAIHTLSKHLTQYPFRRRIKGGGPPQAAHFHPSKPILFVANQRSIRAYDLSRQLLVKILQPGARWISSFDIHPTSSTASGGDNLIVGSYDRRLLWHDLELSQRPYKTLRYHRKAIRAVKFHPGGRYPLFADASDDGSLQIFHGSVTGDMLSNATIVPLKVLKGHKITGELGVLDVDWHPREPWCVSAGADGTCRLWM
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein erb1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.