PharMolix/UniProtQA huggingface dataset:
Protein: PUR5_PSET1
Sequence: MSEQKQSLSYKDAGVDIDAGNALVERIKGVVKKTRRPEVMGGIGGFGALCEIPAGYKQPVLVAGTDGVGTKLRLAIDLKKHDTVGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVDTAADVVTGIGKGCEISGCALIGGETAEMPGMYDGEDYDMAGFCTGVVEKSKIIDGTKVAAGDQLIALASSGPHSNGFSLIRKVLEVSNADTSADFEGKTLGETLLEPTRIYVKPLLELFKHVDVHALSHITGGGFWENIPRVLPASAKAVVKGDSWQWPPIFNWLQENGNITTHEMYRTFNCGVGMVLVVPADKLEQSLSMLKDLGENAWHLGEIQDAAPGEEQVEIVGGAK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH3R1_XENTR
Sequence: MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVSSRNELRCPECRTLVECGVDELPSNILLVRLLDGIKQRPRKAGVGGSAGNSTNVLRAQGSLTTNCGLNDAQNIHGGQQRIQARSPPVRGVPQLPCAKALYNYEGKEPGDLKFNKGDIIVLRRQVDENWYHGEINGIHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFLKDDILTVIRRVDENWAEGMLGDKIGIFPISYVEFNSAAKQLIELDKPSGVDTGEGSSGTTHSSNSQKQADAKKNTKKRHSFTSLTMSNKSSQSVQNRHSMEISPPVLISSSNPTAAARISELTGLSCSAPSQVHISTTGLIVTPPPSSPVVSGPAFTFPPEVTYQAALGDLNPPLLPPPPLATPVITSTSSGAAAAVQRSISGPAEQVTHLRTSTRPSVFVAIYPYIPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVTRALTTATPAKVAMATASSSNVVNLVTPTPPGAPCQKLQGNGAEFAKTVSTNGVPPAGIPGSHIQSSPQAKVLLHMSGQMTVNQARNAVRTAAAHSQDRPTAAVTPIQAQIPSASVLPQQAATSQQMPPPLSGPAAYINAAMNISRPSVPVASAASSSVSSAAFETECNWKSGSGLAACSFPENVSAPLNSAANKQDKDSKKEKKGLLKLLSGASTKRKPRSSPPHSPTQELEQTNSEAALEGAVGPDILPVNGNGRVASCTVDCDLVSASALVQDNRKPASLDTNVPIAPPPRQPCSSLGTVLNDSRPCERYRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI
What is the function of this protein?
Has E3 ubiquitin-protein ligase activity.  In the absence of an external substrate, it can catalyze self-ubiquitination.  Acts as a scaffold protein that contributes to the effective activation of the JNK signaling pathway.
What are the official names of this protein?
E3 ubiquitin-protein ligase SH3RF1, Plenty of SH3s, Protein POSH, RING-type E3 ubiquitin transferase SH3RF1, SH3 domain-containing RING finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the SH3RF family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell projection, lamellipodium. Golgi apparatus, trans-Golgi network.
Protein: UBC28_ARATH
Sequence: MASKRILKELKDLQKDPPTSCSAGPVAEDMFHWQATIMGPSDSPYSGGVFLVTIHFPPDYPFKPPKVAFRTKVFHPNVNSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLVPEIAHMYKTDRAKYESTARSWTQKYAMG
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 28, AtUBC9A, E2 ubiquitin-conjugating enzyme 28, Ubiquitin carrier protein 28.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: ITR2C_FAGES
Sequence: SEKPQQELEECQNVCRMKRWSTEMVHRCEKKCEEKFERQQR
What is the function of this protein?
Inhibits bovine trypsin with a Ki of 0. 174 nM and trypsin-like proteases from G. mellonella larvae.  Has no activity against serine proteases chymotrypsin, subtilisin and elastase.  Has no activity against cysteine proteases from beetle gut.
What are the official names of this protein?
Trypsin inhibitor 2c, BWI-2c.
Protein: ARFF_ARATH
Sequence: MRLSSAGFNPQPHEVTGEKRVLNSELWHACAGPLVSLPPVGSRVVYFPQGHSEQVAASTNKEVDAHIPNYPSLHPQLICQLHNVTMHADVETDEVYAQMTLQPLNAQEQKDPYLPAELGVPSRQPTNYFCKTLTASDTSTHGGFSVPRRAAEKVFPPLDYSQQPPAQELMARDLHDNEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDSVLFIWNDKNQLLLGIRRANRPQTVMPSSVLSSDSMHLGLLAAAAHAAATNSRFTIFYNPRASPSEFVIPLAKYVKAVYHTRVSVGMRFRMLFETEESSVRRYMGTITGICDLDPTRWANSHWRSVKVGWDESTAGERQPRVSLWEIEPLTTFPMYPSPFPLRLKRPWPPGLPSFHGLKEDDMGMSMSSPLMWDRGLQSLNFQGMGVNPWMQPRLDTSGLLGMQNDVYQAMAAAALQDMRGIDPAKAAASLLQFQNSPGFSMQSPSLVQPQMLQQQLSQQQQQLSQQQQQQQQLSQQQQQQLSQQQQQQLSQQQQQQLSQQQQQQAYLGVPETHQPQSQAQSQSNNHLSQQQQQVVDNHNPSASSAAVVSAMSQFGSASQPNTSPLQSMTSLCHQQSFSDTNGGNNPISPLHTLLSNFSQDESSQLLHLTRTNSAMTSSGWPSKRPAVDSSFQHSGAGNNNTQSVLEQLGQSHTSNVPPNAVSLPPFPGGRECSIEQEGSASDPHSHLLFGVNIDSSSLLMPNGMSNLRSIGIEGGDSTTLPFTSSNFNNDFSGNLAMTTPSSCIDESGFLQSSENLGSENPQSNTFVKVYKSGSFGRSLDISKFSSYHELRSELARMFGLEGQLEDPVRSGWQLVFVDRENDVLLLGDDPWPEFVSSVWCIKILSPQEVQQMGKRGLELLNSAPSSNNVDKLPSNGNCDDFGNRSDPRNLGNGIASVGGSFNY
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).  Seems to act as transcriptional activator.  Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.  Regulates both stamen and gynoecium maturation.  Promotes jasmonic acid production.  Partially redundant with ARF8.
What are the official names of this protein?
Auxin response factor 6.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EUTC_RHOP5
Sequence: MTKPTPTIHSLRDLRRLTPARVGLGRSGASVPTKALLDFTLDHARARDAVHASFDGAALTGELSALGLAVHEVRSRVRGRHDYLVRPDLGRQLDPESRDRLAGIGGPGGDLVLVIGDGLSPGAVHARAAAVVGRLLKRLTEAGIAVGPAVVANGARVALGDEIGALLGARMVAVLIGERPGLSSPASLGAYLTYAPRPGLTDAERNCVSNIHPAGLSEDEAAFKIGWLIREALARRLSGVALKDDSMLEAATAARELSAPG
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: AZOR_SHEPC
Sequence: MSKVLILKSSILGGYSQSAVLIDHLASHWENQGAAITVRDLGGKDVLPMVDGEIASGLRGGAELSARQQEMLALSDTLVAELKANDTIVIAAPMYNFTIPAQLKNWIDFIARAGVTFTYTETGSKGLVEGKRAVLVTTRGGAHKDGPTDHVVPYLKTVLAFIGITNVEVVYAEALNMGPEAHDKGMSEAKHSIDLLTA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: DXR_THEPX
Sequence: MKKVIILGSTGSIGTQTLDVIKNFRENFEIVGLTAYNNVELLSKQIREFNPKVVAVKDEDKANQLRENLKKNVEILTGSKGLQEIVKYDADLVVVAVEGIAGLIPTVTAIQMGKDIALANKEVLVTAGQIVMDLVKKKDISLLPVDSEHSAILQCLRGNDKKEVSRLILTASGGPFRGKKKEDLRKVTVNEALNHPNWKMGKKITIDSATLMNKGFEVIEAKWLFDISEDKIDVIVHPQSIIHSMVEYIDGSVIAQLATADMRIPIHYALNYPTRNYINGMNFLDFSLTTQLTFEKPDLETFRCLSLAYEALKIGGTMTTVLNAADEIAVSLFLNKKIEFLQIAEIIEESMKEHNNIQNPTLDDIINVDEEVKEKIAKKYMR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RL14_ROSCS
Sequence: MVQQETRLRVADNTGAKEILCIRVLGGSHVRYGRVGDVIVASVKEATPGGAVKKGEVVRAVIVRTAKEYGRPDGSHIRFDDNAAVIIGKDNNPRGTRIFGPVARELRERAFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MNHG1_STAEQ
Sequence: MIATIVTSVSIIFVVLGALISAFAATGLIRLRDVYSRAHAAGKAATLGAMFLLFGAFLYFIGTEGYVNMQLIIGIIFVFITGPLSSHLIMKAAYNIKTPYTKDTKIDEIKEDMKHTKL
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit G1, Mnh complex subunit G1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FHUE_ECOLI
Sequence: MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETVIVEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEVVRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQQFADTWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRVDTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGTPRNFSITGTYQF
What is the function of this protein?
Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid.
What are the official names of this protein?
FhuE receptor, Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PLPL6_HUMAN
Sequence: MEAPLQTGMMGTSSHGLATNSSGAKVAERDGFQDVLAPGEGSAGRICGAQPVPFVPQVLGVMIGAGVAVVVTAVLILLVVRRLRVPKTPAPDGPRYRFRKRDKVLFYGRKIMRKVSQSTSSLVDTSVSATSRPRMRKKLKMLNIAKKILRIQKETPTLQRKEPPPAVLEADLTEGDLANSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRVTFLALHNYLGLTNELFSHEIQPLRLFPSPGLPTRTSPVRGSKRMVSTSATDEPRETPGRPPDPTGAPLPGPTGDPVKPTSLETPSAPLLSRCVSMPGDISGLQGGPRSDFDMAYERGRISVSLQEEASGGSLAAPARTPTQEPREQPAGACEYSYCEDESATGGCPFGPYQGRQTSSIFEAAKQELAKLMRIEDPSLLNSRVLLHHAKAGTIIARQGDQDVSLHFVLWGCLHVYQRMIDKAEDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKILGNLQQLQGPFPAGSGLGVPPHSELTNPASNLATVAILPVCAEVPMVAFTLELQHALQAIGPTLLLNSDIIRARLGASALDSIQEFRLSGWLAQQEDAHRIVLYQTDASLTPWTVRCLRQADCILIVGLGDQEPTLGQLEQMLENTAVRALKQLVLLHREEGAGPTRTVEWLNMRSWCSGHLHLRCPRRLFSRRSPAKLHELYEKVFSRRADRHSDFSRLARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSASRTKQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMGAKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRPPIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWSRGNVIEKMLTDRRSTDLNESRRADVLAFPSSGFTDLAEIVSRIEPPTSYVSDGCADGEESDCLTEYEEDAGPDCSRDEGGSPEGASPSTASEMEEEKSILRQRRCLPQEPPGSATDA
What is the function of this protein?
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho).  This deacylation occurs at both sn-2 and sn-1 positions of PtdCho.  Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids (PubMed:11927584).  Hydrolyzes lysophospholipids and monoacylglycerols, preferring the 1-acyl to the 2-acyl isomer.  Does not catalyze hydrolysis of di- or triacylglycerols or fatty acid amides (PubMed:11927584).
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein 6, Neuropathy target esterase.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: MIAA_VIBC3
Sequence: MTQKLPLALFLMGPTASGKTDLAIRLRQKYPVEIISVDSALIYRGMDIGTAKPDAQELALAPHRLIDILDPSEAYSAADFRRDALKEMADIVAQGKIPLLVGGTMLYFKALLEGLSPLPAADPVIRQQIELEAEKLGWQALHDQLQQIDPVSAQRIHPNDPQRLSRALEVYRISGKTLTELTQTKGEAIPYRVLQFAIAPKERAELHRRIELRFEKMVESGFEEEVKALYARDDLHPDLPSIRCVGYRQMWDYLDGHGTLDEAIYRGICATRQLAKRQITWLRSWDDLTWLDSENVDQAVETLSNAIASNEISCV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PRIS_METBU
Sequence: MDLKTKYYLKSKFQEYYRTAKIHLPAKLPEREWGVLSFDDMPETVMRRHKSFGSAGEVEDYLTGMAPAHVYYSVAYYTYPNAPTMKEKQWLAADLIFDLDADHIPGAPNSYSDMLDHVKKETLKLYDLLTDDFGFKEEDIGAVFSGGRGYHFHISDPRVLSLESAERREIVDYISGRGLNLDKIFVKKGVSGDAGSEKATMNVFPSEDDGGWGGRINHHMIAYLRELAAKEDAEKLFTGFDRIGKKTAKRIVEILRDETQVDLLKKGNMEALSRVNKDIIQTLAERSVTELSASVDEPVTGDIKRLIRLPGSLHGKSGMCVTSLSISQLEDFDPLNDAIVFSDKPVKLKVIRTFAVQMKGKDLHVEEGVQELPEYAAIYLMCRGAAEYGP
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: VATA_GOSHI
Sequence: MPAVYGSRLTTFEDSEKESEYGYVRKVSGPVVVADGMAGAAMYELVRVGHDNLIGEIIRLEGDSATIQVYEETAGLMVNDPVLRTHKPLSVELGPGILGNIFDGIQRPLKTIAKRSGDVYIPRGVSVPALDKDALWDFQPKKIGEGDLLTGGDLYATVFENSLMQHHVALPPDAMGKITYIAPPGQYSLKDTVLELEFQGVKKQFTMLQTWPVRTPRPVATKLAADTPLLTGQRVLDALFPSVLGGTCAIPGAFGCGKTVISQALSKYSNSDAVVYVGCGERGNEMAEVLMDFPQLTMTLPDGREESVMKRTTLVANTSNMPVAAREASIYTGITIAEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLAARLASFYERAGKVKCLGGPERTGSVTIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLISYSKYSGALESFYEKFDPDFISIRTKAREVLQREDDLNEIVQLVGKDALAETDKITLETAKLLREDYLAQNAFTPYDKFCPFYKSVWMMRNIVHFNALANQAVEKAAGMDGQKITYSLIKHRLGDLFYRLVSQKFEDPAEGEEALVAKFKKLNEDLTAGFRALEDETR
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: SCX6_TITOB
Sequence: MSIFPIILALLLIGLDEGEALDGYPLSKNNYCKIYCPDEKVCKWSCKHRAGATNGKGDCINKGCYCYDVAPGTEMYPGRLPCNPY
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin To6, PT-alpha* NaTx7.5, Toxin Tc43, Toxin To43.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH60_CAMC5
Sequence: MAKEIFYSDDARNRLYEGVRKLNDAVKVTMGPRGRNVLIQKSFGAPSITKDGVSVAKEVELKDTIENMGASLVREVASKTNDQAGDGTTTATVLAHAIFKEGLRNVTAGANPIEVKRGMDKEVAALIDELKNIAKKVSGSKEIAQIATISANSDESIGKLIADAMEKVGKDGVITVEEAKSIEDELNVVEGMQFDRGYLSPYFITNAEKMQVELSNPFILLFDKKITNLKDLLPVLEQIQKTGKPLLIVAEDIEGEALATLVVNKLRGVLNISAVKAPGFGDRRKAMLEDIAILTGGEVISEELGRTLESATLEDLGQASSVVIDKDNTTIVNGAGEKSAIDARINQIKAQIAETTSDYDKEKLQERLAKLSGGVAVIKVGAATETEMKEKKDRVDDALSATRAAVEEGIVVGGGSALILASKRVKLDLSGDEAIGAEIVRRALRAPLRQIAENAGFDAGVVTNAVEVSSDVNYGFNAVSGEYVNMFEAGIIDPVKVERVALQNAVSVASLLLTTEATISELKEDKPMPAMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_PHOLL
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAHVGDIIKVTIKEAIPRGKVKKGDVLKAVVVRTRKGVRRPDGSVIRFDGNACVLLNNTSEQVIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CEP2_HHV6Z
Sequence: MAISTFSIGDLGYLRNFLQNECNWFRICKKTFYREYRSVATSSPIFSLKNKPKKYCMHCEMVVLKRSHEFMFSLAVNGIHFGQFLTGIMKFKKKQVAEGLCYYVLELGSISPVDLSFIPKYNSDCVTSMHCVTPELIYENCSIVCPEEASRLTVKGLGDNKLIPLGGCGVWCLKNGGDLYIYAFVLAYDLYVACYDKTIFPSLAKIVFDMIACDSEDCVFCKDHNKHVSQAGHIVGCVSNQETCFCYTPCQKKMTDINNPELISLLCDQEINKIDIMYPEKKASLSLDINSYVHGYLGDEPCALKCVNWMPIRISSALSRLIILSCPVCKRVVMD
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid.  Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
What are the official names of this protein?
Cytoplasmic envelopment protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus. Note=Localizes in the host nucleus up to 18 hours postinfection, but at later times localizes to punctate, cytoplasmic structures.
Protein: BPD_BPP2
Sequence: MLDALTFDAGSTLTPDYMLMLDSRDITGNISDRLMSMTLTDNRGFEADQLDIELNDADGQVGLPVRGAVLTVYIGWKGFALVCKGKFTVDEVEHRGAPDVVTIRARSADFRGTLNSRREGSWHDTTLGAIVKAIATRNRLEASVAPSLAGIKIPHIDQSQESDAKFLTRLAERNGGEVSVKMGKLLFLKAGQGVTASGKKIPQVTITRSDGDRHHFAIADRGAYTGVTAKWLHTKDPKPQKQKVKLKRKKKEKHLRALEHPKAKPVRQKKAPKVPEAREGEYMAGEADNVFALTTVYATKAQAMRAAQAKWDKLQRGVAEFSISLATGRADIYTETPVKVSGFKRVIDEQDWTITKVTHFLNNSGFTTSLELEVRLSDVEYETEDDE
What is the function of this protein?
Putative baseplate hub protein.
What are the official names of this protein?
Probable baseplate hub protein, Gene D protein, GpD.
What is the protein family that this protein belongs to?
Belongs to the P2likevirus baseplate hub protein family.
What are the subcellular locations of this protein?
Virion.
Protein: GAL1_YERPA
Sequence: MSLKQHTQTIFRQQFDRESDITIKAPGRVNLIGEHTDYNDGFVLPCAINYETVISCGKRDDRQIRVIAADYENQQDIFSLDAPIVPHPEYRWADYVRGVVKHLQMRNADFGGADLVICGNVPQGAGLSSSASLEVAVGQALQSLYQLPLSGVELALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLETRAVPMPENMAVVIINSNIQRGLVDSEYNTRRQQCEAAARFFGVKALRDVEPSLFFSIQDELDPVVAKRARHVISENARTLAAADALAAGNLKLMGQLMQESHISMRDDFEITVPPIDRLVEIVKSVIGDQGGVRMTGGGFGGCIIALMPLELVEQVRTTVAQEYPAHSGGKKETFYVCQASQGAGLC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECM_CERS4
Sequence: MTQKDSPWLFRTYAGHSTAKASNALYRTNLAKGQTGLSVAFDLPTQTGYDSDDALARGEVGKVGVPICHLGDMRMLFDQIPLEQMNTSMTINATAPWLLALYIAVAEEQGADISKLQGTVQNDLMKEYLSRGTYICPPRPSLRMITDVAAYTRVHLPKWNPMNVCSYHLQEAGATPEQELAFALATGIAVLDDLRTKVPAEHFPAMVGRISFFVNAGIRFVTEMCKMRAFVDLWDEICRDRYGIEEEKYRRFRYGVQVNSLGLTEQQPENNVYRILIEMLAVTLSKKARARAVQLPAWNEALGLPRPWDQQWSLRMQQILAYESDLLEYEDLFDGNPAIERKVEALKDGAREELAHIEAMGGAIEAIDYMKARLVESNAERIARVETGETVVVGVNRWTSGAPSPLTTGDGAIMVADPEAERDQIARLEAWRAGRDGAAVAAALAELRRAATSGENVMPASIAAAKAGATTGEWAAELRRAFGEFRGPTGVARAPSNRTEGLDPIREAVQAVSARLGRPLKFVVGKPGLDGHSNGAEQIAARARDCGMDITYDGIRLTPAEIVAKAADERAHVLGLSILSGSHMPLVTEVLAEMRRAGLDVPLIVGGIIPEEDAAELRASGVAAVYTPKDFELNRIMMDIVGLVDRTALAAE
What is the function of this protein?
Radical enzyme that catalyzes the transformation of (2R)-ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA.  Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for R. sphaeroides growth on acetate as sole carbon source.  Is highly specific for its substrate, ethylmalonyl-CoA, and accepts methylmalonyl-CoA only at 0. 2% relative activity.
What are the official names of this protein?
Ethylmalonyl-CoA mutase.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA mutase family.
Protein: FADA_PSEF5
Sequence: MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKLLERNAKVDPAEVEDVIWGCVNQTLEQGWNIARMASLMTQIPHTSAGQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHMGHVSMMHGVDPNPHMSLYAAKASGMMGLTAEMLGKMHGITREQQDAFGVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKLFDYDETIRPETTLESLAALKPAFNPKGGTVTAGTSSQITDGASCMIVMSAQRAQDLGIQPMAVIRSMAVAGVDPAIMGYGPVPATQKALKRAGLGINDIDFFELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTFGVSTMCIGLGQGISTVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM270_HUMAN
Sequence: MEALPPVRSSLLGILLQVTRLSVLLVQNRDHLYNFLLLKINLFNHWVSGLAQEARGSCNWQAHLPLGAAACPLGQALWAGLALIQVPVWLVLQGPRLMWAGMWGSTKGLGLALLSAWEQLGLSVAIWTDLFLSCLHGLMLVALLLVVVTWRVCQKSHCFRLGRQLSKALQVNCVVRKLLVQLRRLYWWVETMTALTSWHLAYLITWTTCLASHLLQAAFEHTTQLAEAQEVEPQEVSGSSLLPSLSASSDSESGTVLPEQETPRE
What are the official names of this protein?
Transmembrane protein 270, Williams-Beuren syndrome chromosomal region 28 protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CHLI_NEPOL
Sequence: MNATITTSEQARPVFPFTAIVGQEEMKLALLLNVIDPKIGGVMIMGDRGTGKSTTVRALVDLLPEIEVVENDPFNSHPYDPELMSDEVREKVHRGESIRTTTTKIPMVDLPLGATEDRVCGTIDIEKALTEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISICHPARFILVGSGNPEEGELRPQLLDRFGMHAQIGTVREPELRVKIVEQRATFDENPKEFRQSYETSQASLTSQLTEARARLRQVQTDYSLRVKISQVCSELNVDGLRGDIVTNRAAKALAALEGRTSVSVEDIGRIITLCLRHRLRKDPLESIDSGEKVQEVFSIVFGTNPL
What is the function of this protein?
Involved in chlorophyll biosynthesis.  Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.  The magnesium-chelatase is a complex of three subunits, CHLI, CHLD and CHLH.  The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step (By similarity).
What are the official names of this protein?
Magnesium-chelatase subunit ChlI, Mg-chelatase subunit I-1, Mg-protoporphyrin IX chelatase subunit ChlI.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
What are the subcellular locations of this protein?
Plastid, chloroplast.