PharMolix/UniProtQA huggingface dataset:
Protein: NCBP2_DROMO
Sequence: MSASIDLSSYRDQHFKGSRSEQERSLRDSSTLYVGNLSFYTTEEQIHELFSRCGDVRIIVMGLDKYKKTPCGFCFVEYYTRAEAEAAMRFVNGTRLDDRLIRVDWDAGFVEGRQYGRGKTGGQVRDEYRTDYDAGRGGYGKLLSQKIAPNTDNR
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROA_LACLM
Sequence: MIEELGLKVKTASKEAAKLSTAEKNTFLQKLADSLVENTDRIISENAKDLAKAKGHGISEIMVDRLRLTAQRISDMATGLRQVAELPDPIGQVLQGFTNLDGLKIVQKRVPLGTVGMIFESRPNVTIDAFSLCFKTGNSVLLRGGSDAIYSNMVLVEIIKENLLSAKITDGVVELLSDTSHAEAEKMMQADKFLDVLIPRGSARLINRVKEKATVPVIETGVGNCTIFVDESADLDMATRIVINAKTQRPSVCNAAESLVVHAKIADEFLPKLQNEINKVHEVEFRADERSLKALSAGIPATDEDFGMEFLDYILSVKTVDNLDEAIEHINTYSSRHSESIVTHDYFNAQKFQDEIDAAAVYVNASTRFTDGFVFGLGAEIGISTQKLHARGPMGLEALTSTKYLIDGCGQIR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_SYNWW
Sequence: MKVQILGMGHSLPERILNNQELEQMVDTSNEWIVERTGILERRIADKDTATSDLCWQAAKMALERSATEAKELDLIIVGTSSPDMLFPSTACIVQDHLGARNAAAFDVEAGCTGFIYALGIAEKFLLSPEYKKILVIGADLCSRFTDYTDRNTCVLFGDGAGAAVVGKGNLGPGILSSYLAADGSGGKHLYMPAGGSALPPSKETVEQRLHFIRMDGNEIFRFATKIVVAVSEKLLSQAGLSYQDVDLFIPHQANLRIIKTAMKRMRIPAEKTLINLDHFGNMSAACIPVGLSMAEEAGKLKKGDLVLMVAFGAGLSYGGILLRWGRDQDVF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y217A_AFV2P
Sequence: MTLKKHRGKMSEKSNVNKKFTNSTQNNSNWSNSPSMINPESFINNPNLIVFKNWVDKLQQEFPTCDVVDSKNNSITIKIRYDDVFRSIYKEVKKSVPDSKVSLKPCNDDKKYGMCMVVKSKTIIVGWEEWGFGKPIEISGEGEFTYYIPLENVINAFDSAWRMNNKGKPLHFKFMTRRLTPRDATTKGVSAEALSSPPTVGEIWHYITIEFVTVTTT
What are the official names of this protein?
Uncharacterized protein ORF217a.
Protein: SCX7_TITOB
Sequence: MSIFPIVLALLLIGLEETEALDGYPLSKINNCKIYCPDDDVCKWTCKHRAGATNGKGDCIWYGCYCYDVAPGTKMYPGSSPCYA
What is the function of this protein?
Inhibits voltage-gated sodium channels (Nav).
What are the official names of this protein?
Toxin To7, PT-alpha* NaTx7.6, Toxin Tc50, Toxin To50.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBC2_WHEAT
Sequence: MSTPARKRLMRDFKRLQQDPPAGISGAPHDNNITLWNAVIFGPDDTPWDGGTFKLTLQFTEDYPNKPPTVRFVSRMFHPNIYADGSICLDILQNQWSPIYDVAAILTSIQSLLCDPNPNSPANSEAARMYSENKREYNRKVREVVEQSWTAD
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 2, E2 ubiquitin-conjugating enzyme 2, Ubiquitin carrier protein 2, Ubiquitin-conjugating enzyme E2-16 kDa, Ubiquitin-protein ligase 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RL24_LEUCK
Sequence: MFVKTGDKVRVIAGKDKGKEGTITKTVAGKDRVVVEGVNIVKKHQKPSNEYPQGGVIDIEAPIHVSNVQLLDPSTNEPTKVAFKIEDGKKVRVSKKSGNVLG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y3766_HALH5
Sequence: MMTIQQQLETVLGDLQKAKPLSSKHLLVIGVSTSEVAGKQIGTNSSKDVAAALYAALFSYQQKTGVALAFQCCEHLNRALVMERDEAEARGYEEVAVIPVRKAGGAMATYAFTQFRDPVIVEQIRADAGIDIGDTFIGMHLKRVAVPVRSSISAIGDAHVTMAYSRPKLIGGVRANYERTEEHESFRC
What are the official names of this protein?
UPF0340 protein BH3766.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: GLHA_CAPHI
Sequence: MDYYRKYAAVILAVLSLFLQILHSFPDGEFMMQGCPECKLKENKYFSKPDAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVTGNVRVENHTDCHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCL14_HUMAN
Sequence: MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN
What is the function of this protein?
Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha.  It induces intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes.  Enhances the proliferation of CD34 myeloid progenitor cells.  The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes, eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
What are the official names of this protein?
C-C motif chemokine 14, Chemokine CC-1/CC-3, HCC-1/HCC-3, HCC-1(1-74), NCC-2, Small-inducible cytokine A14.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB5_RABIT
Sequence: MAAQSDKDVKYYTLEEIKKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELSKTFIIGELHPDDRSKLSKPMETLITTVDSNSSWWTNWVIPAISALIVALMYRLYMADD
What is the function of this protein?
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
What are the official names of this protein?
Cytochrome b5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: HMP_XYLFA
Sequence: MSASFSPHTITLIKSTVPLLAEHGTTIIEAMYHRLFEDPQIEALFNQANQKNGTQIHALAGAILAYARNIDNPGVLASAIERIAQKHVGYAIHPEHYPHVATALLGAIKKVLGDVATSEVLEAWGEAYWFIANLLKDREAVIREGIMTKNGGWIHWRRFVISKRIPESETITSFMLHPEDGGPVVPHQAGQYLTFRFDAAGMPGMKRNYSISCGPNSDHYRITVKREHGTGASAFLHDQAKVGTIIECTPPVGDFFLPSVIERPIVLLSGGVGLTPMVSMMEQIAEAHPDAQVWYVHGTQNRETHAMDAHIRALVSRHKHMKATTFYTQRREADDAEAGFITIDWLRANTPFQKADFYLCGPRPFLRTFVRDLIGAGVPAVQVHYEFFGPMDEEMAA
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: KATG_VIBCM
Sequence: MEHNKAGSSGQCPVMHGGLTSASMSNMDWWPKALNLDILHQHDSKTNPLGADFNYREELKKLDVEALKRDLKALMTNSQEWWPADWGHYGGLMIRMAWHSAGTYRIADGRGGGGTGNQRFAPLNSWPDNANLDKARRLLWPIKQKYGNKISWADLMILAGNMAYESMGLKTFGFAFGREDIWHPEKDIYWGSEKEWLAKSGGENSRYSGQRDLENPLAAVMMGLIYVNPEGVDGNPDPLKTAQDMRVTFARMAMNDEETVALTAGGHTVGKAHGNGKASNLGPDPEGAELHEQGLGWNNHTSRGIGRNTVTSGIEGAWTTHPTRWDNEYFYLLLSYEWQLTKSPAGAWQWEPVNIKEEDKPVDVEDPSIRYNPMMTDADMALKIDPEYRKISERFYKDPAYFSEVFARAWFKLTHRDMGPKARYFGPDVPAEDLIWQDPVPAGRKDYDVNAVKAKIAASGLSISEMVSTAWDSARTFRGSDKRGGANGARIRLAPQKDWEGNEPARLGKVLAVLEKIAAESGISIADTIVLAGNVGIEQAAKAAGVNVTVPFAPGRGDATIEQTDVESFEVLEPLADGFRNWQKKHYVVTPEEMLLDKAQLLRLTAPEMTVLIGGMRVLGTNYGGSQHGVFTDRVGALTNDFFVNLTDMSYTWKPTGRNSYEIVERKSGKVKWTATRVDLVFGSNSILRAYAEVYAQDDNKEKFVKDFVAAWTKVMNADRFDLV
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: YGW7_YEAST
Sequence: MSILSSTQSTILRIPSGLITFLLSKLFLLLRVEPSSASMSISESELLLMGNINDESPKPGKLASAPLASLTNLVFSIDVKGLTLIATTMEDCLVSGTFMLVSIVYSWKENSSS
What are the official names of this protein?
Putative uncharacterized protein YGL217C.
Protein: ARGB_SYNAS
Sequence: MNTIEKPTEKAEILLEALPYIRRFYNRTVVIKYGGHAMVDDELKQSFAKDVLMMKYIGINPVVVHGGGPQIGSFLKKLGKDSKFIQGMRVTDEETMNIVEMVLVGKVNKEIVGLINHAGGKAVGLSGKDGSLIRAEKYYLSAEKAKDTPPEIIDIGLVGKVKEINADLITSLVRDGFIPVIAPTGAGDSGETYNINADIVAGAIAAALKAEKLILLTDVAGVLNKQGELINTMNNMEALEMIHEGVIEGGMFPKVKCCMKSLREGVRKAHIVDGRLKHAILLEMFTDKGIGTELVL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG087_MONPV
Sequence: MPFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLISYFPDRKYHKYISKVFEHVDLSEELSMEFHDTTLRDLVYLRLYKYSKYIRPCYKLGDNLKGIVVIKDRNIYIREANDDLIEYLLKEYTPQIYTYSNERVPIAGSKLILCGFSQVTFMAYTTSHITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGSGTINKILRKIFYSVTGGQTP
What is the function of this protein?
Involved in postreplicative transcription elongation on intermediate and late genes.
What are the official names of this protein?
Late transcription elongation factor OPG087.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG087 family.
Protein: NRDR_MYCVP
Sequence: MHCPFCRHPDSRVVDSRETDEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSREKVIRGVRRSCQGRQVDDDALNLLAQQVEDAVRATGSAEVPSHEVGLAILGPLRELDEVAYLRFASVYRSFSSAEDFEREIQALRAHREVPAQS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: AEP1_DANRE
Sequence: MTYPTNLEIIGGQGGSSFSFTGENNGASLEKIWVWVGGWQIKAVRAWLSDGRDETFGVPSGSHQEYVFTPGECFTSLSLWGNGAGTRLGAIKFKTNKGGEFFAHMTSWGLKTEYPMDVGSGYCLGIVGRGGSDIDCMGFMFLNAVQSTVLTNVNYPTINQLIPKVATEEIKSVSFENKTSVKQEQKVETSKKVIKTSSWSMTKSFSSTFSVEVSAGIPEIAEVSTGFSISFGVESTHSLEQTDEKNETLTTTVEVPPKKKVDVHITIGRASFDLPYTGTVKITCKNGSVLQYETKGQYKGVAYTDIKVNTVEKDL
What is the function of this protein?
Pore-forming protein which might play a role in host defense.  Exists as an antiparallel dimer in solution.  Can also assemble into an octameric pore-like structure spanning the cell membrane.  Oligomerization may be triggered by binding of the jacalin-type lectin domain to high-mannose cell-surface proteoglycans, and also requires a low pH environment.  In vitro, shows high binding affinity for S. cerevisiae mannan and human HIV virus glycoprotein gp120.
What are the official names of this protein?
Aerolysin-like protein, Jacalin-type lectin domain-containing protein 5.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PETM_RIPO1
Sequence: MTAESMMFNGAVLLMVLVLVGLAWGFLLLKIQGGEAE
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 7, Cytochrome b6-f complex subunit PetM, Cytochrome b6-f complex subunit VII.
What is the protein family that this protein belongs to?
Belongs to the PetM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HFLD_ACTP2
Sequence: MATNYHDITIAFAGVCQAVSLVQQFAHKGSADREIFANSIKSLLVTQPDSTLAVFDGQLANLKLGLETVQAQMGSPNGKLDTEIGRYWINVLALSQKLNKNPEAKAKLAERLQQIERQLPLYENDIMADQMIANLAAIYSDVISPLGSKIHVLGLQDYLVRPDIQQKIRASLLAGIRAGILWQQVGGTRWQFLFSRRKILNQAQQFYKSI
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SLYB_SALTI
Sequence: MIKRVLAVSLMGLSLAGCVNNDSLSGDVYTASEAKQVQNVTYGTIVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTIGGGTGRSLATAAGAVAGGVAGQGVQSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSAGQRVVLASNGSQVTVSPR
What are the official names of this protein?
Outer membrane lipoprotein SlyB.
What is the protein family that this protein belongs to?
Belongs to the Pcp/SlyB lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YI49_SCHPO
Sequence: MREPKNAKVLSRLENVLVTQLDVNNFSSIKKSVEKAISHFGRIDVLLNNAGYSVYSPLESTTEEQIHNIFNTNVFGALEVIKAITPIFRSQHNGMIINVSSIGGKMTFPLGCLYYGTKYAIEGISEALTWEMQSIGVKVKIIEPGFTATEFRVEEGAGKHYAEYDNLKQKLYEDLLPKLKTATPPQKIAEVILQAATDESDELRYPTGDYVVEWMALRSKVDDATFLATHRKQMGL
What are the official names of this protein?
Uncharacterized oxidoreductase SPBC1348.09.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RISB_CLOBH
Sequence: MKIYEGRLTAEGLKVGIIVSRFNEFITSKLLAGSIDCLKRHGAKEDNIEVCWVPGAFEIPVIAKKMASKGKYDAVICLGAVIRGATPHFDYVSSEVSKGVAHVSLDKEVPVIFGVLTTDTIEQAIERAGTKAGNKGYDAAMSAIEMSNLMKVLD
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RNK_BOVIN
Sequence: MASLLCCGPKLAACGIVLSAWGVIMLIMLGIFFNVHSAVLIEDVPFTEKDFENGPQNIYNLYEQVSYNCFIAASLYLLLGGFSFCQVRLNKRKEYMVR
What is the function of this protein?
Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds.  Hydrolyzes UpU bonds at a lower rate (By similarity).  Regulates the activity of vacuolar (H+)-ATPase (V-ATPase) which is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).  Required at an early stage of receptor-mediated endocytosis (By similarity).
What are the official names of this protein?
Ribonuclease kappa, RNase K, RNase kappa, V-type proton ATPase subunit f, V-ATPase subunit f.
What is the protein family that this protein belongs to?
Belongs to the RNase K family.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein.
Protein: PG062_FOWPN
Sequence: MEESAGTPFHDPKYFVSPFILNTDEGRYLVLKAIKLCNVRTIDCMKQETSCVLKVDKPQSPCPISSSDSAPKCYMQQTSPQQQRQAPQLRFINTGALSNLFANTTDKAARVINQ
What is the function of this protein?
Plays an essential role in virion assembly and morphogenesis.  Also plays a role in the inhibition of host immune response by dysregulating mTOR.  Sequesters host RICTOR and RPTOR, thereby disrupting mTORC1 and mTORC2 crosstalk.  In turn, blocks the host antiviral response in part through mTOR-dependent degradation of cGAS, the primary poxvirus sensor.
What are the official names of this protein?
Phosphoprotein OPG062, Phosphoprotein F17.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG062 family.
Protein: RM36_RAT
Sequence: MAALFVRSVVASVVDLSRLAVKPRAFSILLGTLPSAKPCAEVRSLLCGGPVLSLQPSLGFKTKGVIKKRCRDCYMVKRRGRWFVLCKTNPKHKQRQM
What are the official names of this protein?
39S ribosomal protein L36, mitochondrial, L36mt, MRP-L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RXLR2_PHYPR
Sequence: MRLLLWVLLVTLVTFLSSGDAAPVDSNKQLERAAINKVTSRNLANDNSLKHEKRFLRGDRSNIVNLKDGDENEERKIGQKMTTALKSIKVWYLKWEQKILLPGFKKMAKKEMTYSKLMDRFRVRMMNSGRWGTPSGFKRYGRLYKDYLISINRADLTV
What is the function of this protein?
Secreted effector that completely suppresses elicitor-induced cell death in host and enhances virulence of P. parasitica.
What are the official names of this protein?
Secreted RxLR effector protein 2.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: RS17_BURP1
Sequence: MNDSVKTSLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYGKYVVRSKKYHAHDEANTYNEGDLVEIQETRPVSKTKAWAVSRLVEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CD123_SCLS1
Sequence: MPAPDIPEVARTETEPLTRLPFEPITKSHILNCSYDKWHAEYRSSTLKSRIIPLTPEFLSYLREDGIVLPSEIATFPPPETYNNNSTSDGWDEDTDTESDPSEKFSEIHKQIQETITELGGSVVPKLNWSAPKDATWISLKQNSMECNTANDVYLLLKSSDFITHDLEHAFDGCAEDPSLTKENIQYVLVLRKWFKVNPSCEFRCFVRDRRIIGICQRDLNYFDFLFPLIPTLREAIQEYFDRTLKDSFPDRNFSFDVYIPEPFDKVRLVDINPWAPRTDPLLFSWLELLTLSVPPPLLGVADSSSVPPLPVQSSDEDDGADDVEELGWMPEFRLIKKDDPEAYSFSSPQYSAHKMPQEVVEAGASGEGGMREFADNWQRMLSGELEMMRAGEDSSDDEDEVEAIVT
What is the function of this protein?
Regulates the cell cycle in a nutrient dependent manner.
What are the official names of this protein?
Cell division cycle protein 123.
What is the protein family that this protein belongs to?
Belongs to the CDC123 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NA239_NEMVE
Sequence: MASFKIVIVCLALLVAVACARRRDMMSDDELDFHLSKRGIPCACDSDGPDIRSASLSGIVWMGSCPSGWKKCKSYYSIVADCCNQ
What is the function of this protein?
Binds to site 3 of voltage-gated sodium channels and inhibits the inactivation process (PubMed:18538344).  Is highly active on DmNav1/TipE (drosophila) and is only extremely weakly active on rat Nav1. 4-beta-1/SCN4A-SCN1B, and on human Nav1. 5-beta-1/SCN5A-beta-1 (PubMed:18538344).  This reveals high specificity for arthropod over mammalian channels (PubMed:18538344).  In vivo, when released into the medium, this recombinant toxin induces impaired swimming, paralysis and death of the crustacean A. nauplii within several hours (PubMed:22048953).  Also causes paralysis of cherry shrimps immediately after injection at very low doses (PubMed:29424690).  Its effect on zebrafish (D. rerio) larvae is also rapid, since it induces tail twitching accompanied by impaired swimming after 20 minutes and complete paralysis within 45 minutes (PubMed:22048953).  It has also been observed to cause death of zebrafish larvae within 1 hour (PubMed:31134275).
What are the official names of this protein?
N.vectensis toxin 1 5, Nv1, Neurotoxin Nv1-116.39.1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSTX1_HAESL
Sequence: MRTLLVFLLLAIFVAVLIGNVQVEAACKEYWECGAFLFCIEGICVPMIG
What is the function of this protein?
Leech salivary gland peptide with unknown function (PubMed:32524995).  It was originally described as exhibiting analgesic function by specifically inhibiting rodent Nav1. 8/SCN10A and Nav1. 9/SCN11A voltage-gated sodium channels, as well as showing analgesic activities in several mouse models (PubMed:29559913).  In a second study, the synthetic peptide has been shown as having very weak activity on Nav1. 8/SCN10A at the highest concentration tested (90 uM) and as being only very modestly active at hNav1. 9/SCN11A, with a modest peak current size reduction (~19%) at high concentrations (10 uM) (PubMed:32524995).  In addition, this second study reports no analgesic activity in a mouse model of inflammatory pain (PubMed:32524995).
What are the official names of this protein?
Peptide HSTX-I.
What is the protein family that this protein belongs to?
Belongs to the annelide toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YJ026_YEAST
Sequence: MAGSGLFFKWANNKHAKSVCKPSSLQINSLEKVKPGIIPLFFNQKMEAKEPEKKTPSMEAKATSLSPNKASAS
What are the official names of this protein?
Putative uncharacterized protein YJL026C-A.
Protein: HISX_SULDN
Sequence: MIFTTSKNSSFKAEFKELLERGKMDIAHVSATVGTIIDEIKSNKNQALKEHITKFDKWTPVSDEDLKISTESMSRAYENLDKALKAALHLSYDRIKAYHEKQKPRSWFDDEPNGTILGQRVTPVDSAGLYIPGGKAAYPSSLLMNVIPAQVAGVQNIVVCTPTPENEPNELLLAACHLCGVSEVYKVGGASAIAAMAYGTETIPKVDVITGPGNIFVATAKKMVFGDVNIDMIAGPSEIGILADDSANPSHMAVDMLSQAEHDEMASSILITPSQKLADAIKAEIENWLKILPRQKIARESIEKRGAIIVTSDMQEAIDLMNEIAPEHLEVATLSPFELLPLIKHAGAIFLGHNTPEAVGDYMAGPNHTLPTGGTAKFFSPLGVENFMKKTSIISFSAKAINEIGEECALIAKIEGLTAHEQSIRVRLVK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.