PharMolix/UniProtQA huggingface dataset:
Protein: RIMM_SALRD
Sequence: MPPPTASTPDDSADPGPDFADVPPTDLVKVGFIFRPHGLDGELKIDPSATDDPARFEVLPTVFVGPHPRRVVRHDIASVRYQKTKRGITVILGLDGIVDRDDAEAVAKMDVFATEAALGLEDDELFADDLVGWTVVTEEGAVQGTVADFMEMPAQDLFVVRTPEDTEAMIPAIDDFIIEIDEEAERIVVRPIDGLMDA
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOL5_BOMPE
Sequence: INVLGILGLLGKALSHL
What is the function of this protein?
Mast cell degranulating peptide.
What are the official names of this protein?
Bombolitin-5, Bombolitin V.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Bombolitin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIR2_CAEEL
Sequence: MTLTEIQNVEKENAGASVPKHSSNKLKLEKELEKLEIVDQTKAASAEETNNESEVNELDADEPMLQDLDNRFVIFPLKHHDIWNFYKKAVASFWTVEEVDLGKDMNDWEKMNGDEQYFISRILAFFAASDGIVNENLCERFSNEVQVSEARFFYGFQIAIENIHSEMYSKLIETYIRDETERNTLFNAVDEFEFIKKKADWALRWISDKKASFAERLIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTHSNELISRDEGLHRDFACLLYSKLQKKLTQQRIYDIIKDAVAIEQEFLTEALPVDMIGMNCRLMSQYIEFVADHLLVELGCDKLYKSKNPFDFMENISIDGKTNFFEKRVSEYQRPGVMVNEAERQFDLEADF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: ANX10_HUMAN
Sequence: MFCGDYVQGTIFPAPNFNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTREEGYTDPAMAAQDAMVLWEACQQKTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVLCVRDKPAYFAYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIRNFASGHYKKALLAICAGDAEDY
What are the official names of this protein?
Annexin A10, Annexin-10, Annexin-14.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
Protein: HIS4_METLZ
Sequence: MEVFPAVDILSGNCVQLVGGDRLTATVYGSPMDNARRWISEGASNLHVVNLDGAFTASTTNAEMIREVVEKTDVFVQVGGGIRSLEDARGWLNCGVARIILSTFATREPAVIRTLSKEFGSERIMAGVDARRGEIAVSGWQELAGDFIVWAQKFEELGAGSLLYTNVDVEGQQAGIDIEPVQKLLDAVDIPVIVAGGVTTSQDVTALKQLGASGCVLGSALYSGRITLKEALEAAV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2180_SULIY
Sequence: MKRLPAVAGSFYESDPKKLKMQIEWSFRHNIGPRDIPKQTYEKKKRDNLFFVVPHAGYIYSGPVAAHSYYYLVSEGRPDVVIILGPNHTGLGSYVSAWPKGEWETPLGSVKIDEEILMQLVKESEVIDLDEKSHLYEHSIEVQLPFLQHFFDDDFKIVPIVIMMQTPEIAEFLADAIYNVMQKNPDKDIVVLASSDMNHYDPHEITVKKDVEAIEKIQQLDYKGLYEVVEGKDVTLCGYGPIMVNLILAKKFGKKAYILKHATSGDTSGPKDSVVGYLAARFGS
What are the official names of this protein?
MEMO1 family protein YG5714_2180.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: DER_POLNS
Sequence: MNPVITIVGRSNVGKSTLFNRLTRSRDALVADFSGLTRDRHYGKCRIGERAFICVDTGGFEPVAKTGIVAEMAKQTKQVVAESDIVIFLVDGRLGMAPQDRVIADFLRKTGRPVILAVNKTEGMQASVVTADFHELGLGEPFPISSAHGDGVRGLIDDALDSLGVAEPDEDELVNDPNRPMKIAVVGRPNVGKSTLINKLIGEERVIAFDMPGTTRDAIEVPFERNGKPYILVDTAGLRRRGKVFEAIEKFSVVKTLQAIADCNVVILMLDAQQDISEQDAHIAGFIVEAGRALVVAVNKWDGIDTYVKERARLEIAQKLRFLDFANVHPISAKKGTGLKDLFKDVDAAYAAAMAKLPAPRLTRILQEAIEHQQPKRVGMGRPKLRYAHQGGMNPPIVVIHGTSLSGVTDSYKRYLEGRFKDVFKLRGTPLRIQMNTAKNPYVDADKGKKGKKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ARGB_VEREI
Sequence: MTDPLSIAPRDQAEILARALPYIRRFHGKTMVIKYGGNAMTDPALQADFAEDVVLLKLVGMNPVVVHGGGPQIETALNRLGKKGVFIQGMRVTDAETMEVVEWVLAGQVQQDIVGLINQAGGKAVGLTGRDGAMIRAQKLKMVDSKDSSIEHDIGQVGDIVSIDPSVVKALQDDAFIPVISPIGFGENNESYNINADVVASKLATVLQAQKLVLLTNTPGVLDKKGNLLTDLTAREIDALFADGTISGGMLPKIAGALDAAKAGVHAVHIIDGRVPHAMLLEILTDQAFGTMIRSH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_SALHS
Sequence: MNLNATILGQAIAFILFVWFCMKYVWPPLMAAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRAQILDEAKTEAEQERTKIVAQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AZUR5_PSEPU
Sequence: MFAKAVAVSLLTLASAQVFAADCKVTVDSTDQMSFNTKAIEIDKSCKTFTVELTHSGNLPKNVMGHNLVISKEADMQPIATDGLSAGIDKDYLKEGDDRVIAHTKVIGAGEKDSVTFDVSKLKADEKYGFFCSFPGHISMMKGTVTLK
What is the function of this protein?
Transfers electrons from cytochrome c551 to cytochrome oxidase.
What are the official names of this protein?
Azurin.
What are the subcellular locations of this protein?
Periplasm.
Protein: GATB_SYNS9
Sequence: MADAATQLPWEAVIGLETHVQLGTDSKIFTAASTTFGDEPNTHIDPVVCGLPGTLPVLNQKVLEYAVKAAMALNLNIAEHSKFDRKQYFYPDLPKNYQISQFDQPIAEEGWIEVEVAEKGKDTYLKTIGIERLHMEEDAGKLVHAGSDRLAGSTHSLVDYNRAGVALAEIVSKPDLRTGREAAEYASEIRRIMRYLGVSDGNMQEGSLRCDVNISVRRGPDAPFGTKVEIKNMNSFSAIQKAVDYEIKRQVKAYETGEPVVQETRLWDEGKQLTKSMRSKEGASDYRYFPDPDLGPIEVSPEQREGWRAELPELPAAKRHRYADDLGLSQYDARVLTDERQMADYFEAVVTAGADAKLSANWITGDLAAYVNSNRLSFAALPFRPEQLSEMVQLIDGGKISGKIAKEILPELLEKGGSPKAIVDERGLGMISDPAAIEAIVDELLGAHPEEVEAFRGGKTKLQGFFVGQLMKKTGGKADPKLANQILSQKLKGG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LIPA_CANDC
Sequence: MITRNSIILRRLYPTAIIRTLATDATESTVVKTKRRRTIFTDELNKGPSFDDFVSGKAKDMLEDPLETARKDPNAKLPSWLKVPIPKGKSFHNVKKDVRELKLATVCEEAKCPNIGECWGGKKSEATATIMLLGDTCTRGCRFCSVKTNRKPAAPDPMEPENTAEAISRWGLGYVVLTTVDRDDLVDGGARHLAETVQKIKQKAPQILVEVLGGDFRGDLSMVEILANSGLDVYAHNLETVEALTPHIRDRRATYRQSLAVLERAKQTNSSLITKTSLMLGFGETDDQVKQTLRDLREIGCDVVTFGQYMRPTKRHMKVVEYIKPEKFDYWRDTALDMGFLYVASGPLVRSSYKAGEAFIENVLKKRKHNVGETPRLAQEIKPSIY
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RBR_HIEPI
Sequence: MEDLQPINPNTDSPTETGATTIEARFSYFCKGRLTMDDNALEEAMKLFNQSKHLFMTNASALGSGTPEEAEHYWFAFILFSMKRLSKKNDAEDAAKSNENSFKLYQILRVAKLNFVDFFKELPQFIVKTGPILSNLYGSDWETRLQAKELQANFVHLSLLSKYYKRAFKTLFKPSHDNVEGQSAVANSADYISNCHRFGWLLFLALRVHAFSRFKDLVTCTNGLVSILAILIIHIPARFRNFSMSDSSHFVKKDDKVVDLLASLCNMYETSEDELRKTMVRTNIVVEEILKKDPSMASECTNGNLDNIDTDDLTYFQDLLEEQSLSSDLDILEKDYDDAMLLEGELDERLFINDEESLLGSSSLSGGAINMTGTKRKIDSMTSPTKTITSPLSPYKSPSKMISTPVSTAMTTAKWLRTVVSPLSSFPSVDLTRFLQSCDKDVTSDVIKRARIILEAIFPSSGIPDRTVLSNTQTTNLMDNIWAEQRRLEALKLYYRVLHAMCKAESQILHGNNLTSLLTNERFHRCMLACSAELVLATHKTVTMLFPAVLERTGITAFDLSKVIESFIRHEESLPRELRRHLNSLEERLLESMVWEKGSSMYNSLTIARPNLSNEINRLGLLAGPMPSLDAIALQCNMSCGGLPPVPKRDTSPGKSGEIRSPKRVCNEYRSVLVERNSFTSPVKDRLLGIGNLKSKILSPALQSAFASPTRPHPTRGETCAETAVNLFFSKIVKLAAVRINGMVERMQLTQQIRERVYCLFQQILGQRTSLFFNRHIDQIILCCFYGVAKITQLSLTFKEIIFNYRKQPHCKPQVFRAVFVDDRSSSRRGKTGQDHVDIIMFYNEIFIPSVKPLLVELAPSNVPKNPNNQVSETNKKDESGPCPCPGSPKVSSFPSLPDMSPKKVSAVHNVYVSPLRSTKMDALISHGSKSYYACVGESTHAYQSPSKDLTAINNRLNGTRKVRGSLNFDEVDVGLVSDSLVSQSLYLQNGKGPASSSGQELKTE
What is the function of this protein?
Regulator of biological processes that recruits a histone deacetylase to control gene transcription.  May play a role in the entry into mitosis, negatively regulating the cell proliferation.  Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).
What are the official names of this protein?
Retinoblastoma-related protein.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_PSEFS
Sequence: MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRTVQDIRNLLNAGADKVSINTAAVFNPEFVGEAAQHFGSQCIVVAIDAKKVSGPGETPRWEIFTHGGRKPTGLDAVEWAMKMEGLGAGEILLTSMDQDGMKNGFDLGVTRAISDALGIPVIASGGVGNLQHLADGVIEGHASAVLAASIFHFGEYTVPEAKAYMAARGIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TL19_ARATH
Sequence: MATKIFLASPVISATRTPIVPKAIASRLGTSLAAALAATSVLTMVPVLPAAGEGNQTYKIYYGTAASAANYGGYGGNSDRKTSAEYVYDVPEGWKERLVSKVEKGTNGTDSEFYNPKKKTEKEYLTFLAGFRQLAPRDVILNNLALSDVELQDLIAGADKVVSEERKDETGQVYYLYEIDGVGKHSLITVTCSKNRLYAHFVNAPAPEWNRDHDTLTHLRDSFKTVSSS
What are the official names of this protein?
Thylakoid lumenal 19 kDa protein, chloroplastic, P19.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: DYR_MYCBO
Sequence: MTMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: PSBL_ZAMFU
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYSFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: INSB_HAEDU
Sequence: MPGNSPHYGRWPQHDFTSLKKLRPQSVTSRIQPGSDVIVCAEMDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element IS1 protein InsB.
What is the protein family that this protein belongs to?
Belongs to the transposase 27 family.
Protein: G2L2S_XENLA
Sequence: MSTHQGGSVHSIRPFKSSEEYLYAMKEDLAEWLKDMYHLEIIVDNFIEILENGSVLCQHANNVTEVAREFFVQYPHLAEKLQLPKSGVKLNMMAQPGSFLARDNVSNFIQWCRKEMDIKDVIMFETEDLVHRKNEKNFLLCLLELARRASRFGMSAPMLIQMEEQIEEEIRQEMDLPPQEIPVPKPQRKLCDFKNLDQMVQNLVSRCTCPVQFSMVKVSEGKYRVGESSTLIFVRILRKHVMVRVGGGWDTLAHYLDKHDPCHCASLSHKPAIKLGSLQKQVSAVHEVKTQLTPRLDNPSKLETTLILSRSQSPLPPVEWRTYSAERTRTISSSYSLDDNENSPSFKNSQTPPNDRRSMSIGAHERSATLSRKLFTEDTQDPQQLGNPQSGHYRHHHSTSSLASQLTGSEEEYSYISEVFSESQSGRQMGKHTVMNLKEPPKRDAFLSHTQSANRKVISATQQNNIQQGLIIGHQSVTVQDSRPKTPSRFIQPPSPSKQIHFFYNQQNKGVEQNIKTQTNSCTRSSSPVKQTSLTYKQEFNKRPATPSRINYSSSQYKDGDKSAATEIITFHDHVRAKPSVSSEERTIRTGRATPTIHLNRENTNLPLKMQPKPNVTESSHSIERDCMYTPLPIDPEQEKQIYRSLEDEIRTNIKILEGDSEENNPENDTAAHDFNVLGKSTLRLSSSTSKTPRGQEGVPRSGVYINTAWQSGASYDDVITELTKGHVKLNNVDVENWISKIPLKGMVKEAHTSQRNKVRENGHTASLVRKKTLSTEMKGSKQKQLPSQIARQLALENKKKTVENVLEKQVSTVSGDSKEAIPEKIKLSQGLKPKKSLKKPERVPSIYKLKLRPKIRPRRDNRPEKKPSRIPTPVSYRQVPSRNNAKALKRTQSYQANKVSVAQTLNESQISAVNSEDLDSGDEICEHSAPLQAVETPITGENNQSRTEEEEESWV
What is the function of this protein?
Together with gas2l2. L, regulates ciliary orientation and performance.
What are the official names of this protein?
GAS2-like protein 2B, growth arrest specific 2 like 2 B.
What is the protein family that this protein belongs to?
Belongs to the GAS2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium basal body.
Protein: Y1322_LISMF
Sequence: MLEKAKIDRINELSKKKKAGTLTATEKVEQDKLRKEYIKSFRTHMKGTIENTTIIDPNGTDVTPHKVKQLRKNKH
What are the official names of this protein?
UPF0291 protein LMOf2365_1322.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAMB_KLEPN
Sequence: MMITLRKLPLAVAVAAGVMSAQALAVDFHGYARSGIGWTGSGGEQQCFKATGAQSKYRLGNECETYAELKLGQELWKEGDKSFYFDTNVAYSVNQEDDWESTSPAFREANIQGKNLIDWLPGSTLWAGKRFYQRHDVHMIDFYYWDISGPGAGLENVDLGFGKLSLAATRNSESGGSYTFSSDDTKKYAAKTANDVFDIRLAGLETNPGGVLELGVDYGRANPQDDYRLEDGASKDGWMWTGEHTQSIWGGFNKFVVQYATDAMTSWNSGHSQGTSIDNNGSMIRVLDHGAMDFNDDWGLMYVAMYQELDLDSKNGSTWYTVGVRPMYKWTPIMSTQLEIGYDNVKSQRTSENNNQYKITLAQQWQAGNSVWSRPAIRIFATYAKWDENWGYSNTSGLQTKDSSGSGAFTSSRGDDSEVTFGAQMEVWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.  Does not act as a receptor for phages.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SOPB_SALDZ
Sequence: PAKEAYRLAAATFRDAQVKHLNSQPWQTIKNTLTHNGHQYTNMQLPAADMKIGTQDIFPSAYQGKGVCSWDTKNIHHANNLWMSTVSAHEDGKDKTLFCGIRHGVLSPYDVKDPLLRQTGAENEAKEVLTAALFSKPELLTRALEGEAVNLKLVSVGLLTASNVFGKEGTMVEDQMRAWQSLTQPGKMIHLKIRNKDGELQTVKIKPEIAAFNVGVNELALKLGFGLKTSDSYNVEALHQLLGNDLRPEAKPGGWVGDWLAQYPDNYEVVNILARQIKDIWKNNLHHKDGGEPYKLAQRLAMLANEIDAVPAWNCKSGKDRTGMMDSEIKREIICLHQTHTLNAPGSLPDRSGQEIFQKVLLNSGNLEIQKQNTGGAGNKVMKNLSPEVLNLSYQKRVGDENIWQSVKGISSLITS
What is the function of this protein?
Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2.  It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC).  Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements.  The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell (By similarity).
What are the official names of this protein?
Inositol phosphate phosphatase SopB, Effector protein SopB.
What is the protein family that this protein belongs to?
Belongs to the phosphatase IpgD/SopB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
Protein: OTSA_ECOLC
Sequence: MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSGETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPAWDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPTPEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKAFRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLAYEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLYYLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAANELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISDLKQIVPRSAESQQRDKVATFPKLA
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose.  Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Acts with retention of the anomeric configuration of the UDP-sugar donor.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: YAHN_ECOLI
Sequence: MMQLVHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQTSLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAWCSMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTWARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYEGVTQR
What are the official names of this protein?
Uncharacterized membrane protein YahN.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCIB_BUCAT
Sequence: MKQILNILPMFIFFIFYKFYDIFIASGSLIVISGLICIIHWIFYNEIDKISLFSFLSVFFFGSLTIFFHNSQFIKWKITIIYIIFSLVLLISQFFTRKPMIQRFLEKDIKISNIYWRKINFIWSLFFLFCAILNIYIAYYFSETIWVNFKVFGFTSLTFFLILITSIYINCKISKNK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNZ_LACDB
Sequence: MELEFLGTCSGQPSKLRNVSSLALKLLDELNEIWLFDCGEATQHQILRTNIRLRKITKIFISHNHGDHIFGLPGLLSTRSFQGDVGPLTIYGPAGIEQFVKTSLRISKTKISYPIKFVTLEEGGKIVSERGFEVYTEKLDHRIDSWGFRMVEADKAGELLMDKLAEFKVPNGPLLGKLKRGEQVELADGTVLNGKDFLGPAKKGRVVTVIYDTRSTPSIRRLADHADVLVHEATFDASEGKLARDYYHSTCTQAAETASACHVGHLYLTHVSARYVGSLASQMVKQAREIFPATTLAKDLDKFVVPMKG
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: IL3_SHEEP
Sequence: MSSLSILHLLLLLLSLHAPQAQGLPLRTPRTPYSSLMEEIMDDLKKITPSPEGSLNSDEKNILANKSLLQANLKAFMTFATDTFGSDSKIMKNLKEFQPVLPTATPTEDSILIEDSNLGDFRMKLEEYLATIRGYLRHDLAAAETI
What is the function of this protein?
This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
What are the official names of this protein?
Interleukin-3, IL-3, Hematopoietic growth factor, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor.
What is the protein family that this protein belongs to?
Belongs to the IL-3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPCS3_CANLF
Sequence: MNTVLSRANSLFAFSLSVMAALTFGCFITTAFKDRSVPVRLHVSRIMLKNVEDFTGPRERSDLGFITFDITADLENIFDWNVKQLFLYLSAEYSTKNNALNQVVLWDKIVLRGDNPKLLLKDMKTKYFFFDDGNGLKGNRNVTLTLSWNVVPNAGILPLVTGSGHVSVPFPDTYEITKSY
What is the function of this protein?
Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:3511473, PubMed:8444896).  Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 3, Microsomal signal peptidase 22/23 kDa subunit, SPC22/23, SPase 22/23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: PSBF_ASACA
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: IOLH_BACSU
Sequence: MKLALDPSMYRDDLTLEEMVYKTAELGYEYIELSPREDFCPFYKYPKVDSAKIKQLKRLLRDTGVKLSSLLPLYHWAGPDEDRRQAAVRNWKRAIEIAVELEVDLMNSEFSGSKYDPLTSEEKFIKSMDELLPVFEKEGIKLNLQAHPYDFIETHKGAMDMIRALDKDWINLVYSTAHTFFYDDGKGDIETMFDEAGDRLTHVLFADTYNHKAAHGLRYIVNPPDAKVTVHQHLDIGQGEVDFDTIFRKLREMKFDGIATNAVFAWVDERADESSRFMLKKMKEELGLA
What are the official names of this protein?
Protein IolH.
Protein: ACP_AROAE
Sequence: MENIEQRVKKIVAEQLGVNESEIKTESSFVDDLGADSLDTVELVMALEEEFECEIPDEEAEKITTVQQAIDYVTAHLKK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2085_DESVV
Sequence: MTMQGNKLVNLGFGNFVVASRVVSIVDPDSSPMRRLREDARDQGRLIDVTQGRKTRSIIITDSNHVILSAIQTETMGQRFTQEDED
What are the official names of this protein?
Putative regulatory protein Dvul_2085.
What is the protein family that this protein belongs to?
Belongs to the RemA family.