PharMolix/UniProtQA huggingface dataset:
Protein: METAA_BACSU
Sequence: MPINIPTHLPAKQVLESEHIFVMDESRAFHQDIRPQKIIILNLMPKKIQTETQLLRLLGNSPLQVHFTFLIPSTHTPKNTAREHLDEFYTTFSNIRHKRFDGMIITGAPIEHLAFEEVSYWEELKEIMEWSKTNVTSTLHICWGAQAGLYYHYGVEKIQMPKKIFGVFEHTVLSKHERLVRGFDELYYVPHSRHTDINMEQLQAVPELNILTASKEAGVCLIVSKDEKQVFLTGHPEYDTNTLLQEYERDLERNLSTVEAPKHYFAKGSNEPVNRWKAHATLLFMNWLNYYVYQETPYEWD
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FP_ACRMI
Sequence: MWQILLAISIFSLSKLSNAQQQPKVAPPQITNFLAEDKVAPEEVKFRDTDVWQLVLPCRATGSNPLKWVWKHNNAEINKNKFIFDRDWELLSDGTLRARGLNISDRGTYQCFVEDTVTKVSTFSRKLRVEVTAVGDFKSHKDFTSSVKLGEPLNVECPPRGPSFGVTFAWTSKKARSIQFPISNRVAIDPSTGNLHIMYITEEDVSTFNDLEGIRCTISAANTFYSSGALTLQIIPGKEIKLSSPSFTSSTSSPNENAVEGRRKDLYCEATARPPPKLVWKKNGVELKSGIDFIEIPEAFEGRLLSITSVKESLHETTFTCEASNNQTIASGPAQQNFVLNVEVAPRWASKPPDSLKEIPISSNGNLSCDVYAQPEPEIKWYRDGREITQSSSKVEVSGSKLLFKDTTLDEAGIYQCSAENVHGMIVSSTYVKVLAIAPSFKNGFGPFYLFQDSEGRLKCDPEAAPRPSTFKWFDENGAEIKSGNGYTIEEDGTLVITKVERSQHAGKFSCYAKNFLGNATAEGTATVYDRTRIVRGPSDLSVNEGTRVDLRCEAVADSSLELHYTWKRDDATIEYNRRVQWLKDQNVLTIADLTVEDAGIYTCVAYTPQPKYSEAKASAIVNIAGAPFPPTNLMLSSECQNRNTTLSWVTGESNNASILYFLIERKSQYADDFWQVIANVTNPNATSHPLVKLAGNADLAFRIRAVNRFGPSRPSEPTGSFCRTIRAVPEKWPDNFRGVPGKAEELTIAWTAMRRVEWNGPGLYYKLWYRRVNSGDALVEVRREASSDSFVVPDAGYYRQWEFQIQAINEVGEGPKSPLVKQFSGQDPPTGKPEDVTVGTITARSVELSWKKVTFTRGSVDGYRIYFWGESRVSAKRRRRAIPGYASVTNVTGVNTERYTVTGLKPYTNYKFVITAYNSGGNGPESDQVAADTDEAEPGPPSDVQVFVFAKYILVTWQPPSEPNGVITNYRVGTETYTGSQPTDVTVNMEETGVEARRKLLRDLVPETNYVVEMQAATSKGWGTSFRKTEKTVAWAAPAKPEKPIVEGTAVDEVRVDYKFGLGGGYTHDFLVMFRKKIEGQEFQNTSWVDHFQQQSIIIGNLDPELYQFKTVARNDYPSQENPQESPASDITEARPRPGISNVGKRVSTPIYQSAWFIALLVLIALLLLVLLTFVLYTRHQGAKYLVGKREKKRAAALIDREHFDEEEGSFSNNGRADHPPPYPSQGSLPRGADSDRDSLDDYGEGPQFNEDGSFIEEYGDEKKAPPEEKDPSSLATFV
What are the official names of this protein?
Fibronectin type III domain-containing protein, Neuroglian-like protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Note=Presence in the organic matrix of the skeleton may be due to shedding of a soluble peptide.
Protein: LEPA_KLEP3
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMAAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVADEIEDIVGIDAHDAVRCSAKTGVGVPDVLERLVRDIPPPEGDPDAPLQALIIDSWFDNYLGVVSLVRIKNGTMRKGDKIKVMSTGQVYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDILGAPVGDTLTAARNPADKALPGFKKVKPQVYAGLFPVSSDDYENFRDALGKLSLNDASLFYEPESSTALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSKEVIYVDSPSKLPPLNNIQELREPIAECHMLLPQEFLGNVITLCIEKRGVQTNMVYHGKQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASNMVRVDVLINGERVDALALITHNDNAPYRGRELVEKMKELIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLQKQKEGKKRMKQVGNVELPQEAFLAILHVGKDGK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MATK_MEMEL
Sequence: MDKFQRYLDLNRAWQDNFLYPLLFQEYIYTIAHDHALTRSIRSILFENVGYDLKPSSIIVKRLIIRMYQQNPLIILDTDSIPNRFFAYNKNFYSQILSEAFAVIVEIPFSLQLVFSLERKEIDKFRNLQSIHSIFSFLEDKLVHLDXIPVSNVLIPYHIHLEILAQTLRYWVKEASSLHLLRWFLYEYCNWKSLILPKTDIWFFSKRNPRFFXILYNFHICEYESIFFYLRNQSSHLRSTSSGFFLQRIYFFXKXXNLVKVFIHXXFQDILEFXXXAFMHYVRYQGKSIIYSNNTTILMNKWKYYFIHLYQYHYYMWSQPGRIDRNQLCKQPLDFLGYLSSVPITSSLVRTQMVENAFLIDNAMKKLETRVPIIPMIESLSKAKFCNALGNPISKPTWADSSDSDIIDKFLRICKNLSRYHSGSSKKKTLYRVKYILRLSCLKTLARKHKTTGRVFLKQLGSEVFEEFLRREEVVLSLIFSRNDLTPGSLYRGRIWYLDITSINDLVNLK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL21_SALEP
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETIEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RLMN_WIGBR
Sequence: MCLPLILTIKIINIIINMFNKTNKKINILGKTREELYDFFIKIGEEKFRAEQIMKWIYKRYCDDVSLMTDFSKNLKNKLKNIIKIDHLDIESENISQDGTIKWVLKINDQNIETVYIPEINRATLCISSQIGCALNCKFCATSYQGFNRNLNSYEIISQIWYAMKIINDRNNFKLKKITNIVMMGMGEPLLNLKNLVPAIKIILDNYGFGLSKRRITISTAGISPVIKKLGKLIDVKLAISLHAPNDIIRNKIMPINKKYNIKSILLSAKKYISTSKANKGKISIEYIMLNEINDKTEHAYQLINCLKNIPCKINLIPWNPFPYVKYKCSNFNKINNFYKILIKHGITTTIRKQRGIDIKAACGQLSGNVINRINKRNIINF
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNAAH_MYCPN
Sequence: MIFGGAFDPLHQAHIYIAKRAVQAIKAQKLYFVPTAKAFFKSPIKASNQARLAMLRVALKALPQMAVSNFDIKAQNGFSFNTVQHFKQRFPNAELYFLIGSDKLSELAKWHNIEQLQKLCRFVCYERFGYPIDEQLVQQFNVRLLGKCPLDLASSEMFGSHKFRQIPAKVLHYIHQHNIYLKTILQTLLDEPRMQHCLRVGQLAKTLAVANKLDGKTAYTAGAYHDLAKQLPQAQLEKLAKVAGVNDYPSWKVLHSYAGAYILKHWYGLNNSAVFSAIWNHTVPPQKMSQLDMIIYLADKLEPMRVHEEWAKGIDITALVKLAKKDLKLAYQITLKYVRSLQKN
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield ADP.
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase/Ap4A hydrolase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Ap4A hydrolase YqeK family.
Protein: RIBA_SHEPW
Sequence: MSIKYIASSKLPTPWGVFEMHGFEDSETGKEHVALTLGVFDAESPILGRIHSECLTGDALFSLRCDCGFQLQTAMQNIAEAGQGFILYLRQEGRGIGLLNKIRAYELQDGGANTVEANERLGFAADMRKYDMIIPMMEQIGISKVRLMTNNPRKVKAMQSFGLEVVERVPLQVGKNRYNEGYLKTKSTELGHMMSEHHFTEEGKD
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: DNAA_FRAP2
Sequence: MTTWNKCLKKLKKSLSTFEYKTWIKPIHVEQNNYLFTIYCNNEYFKKHIKSKYGEIISSTIQEFHDGDLLIEYSNKKFSGEKSPEVTSVGPQANFFNQKNVEIKDDSEETSLNQEPKKSQKKLSSKNSASQELFGFDEAMLITDKDDQEYSFGLPLKEKYVFDSFVVGDANKIARAAAMQVSINPGKLHNPLFIYGGSGLGKTHLMQAIGNHAREVNPNARIIYTNSEQFIKDYVNSIRLQDQDEFQRVYRSADILLIDDIQFIAGKEGTAQEFFHTFNALYENGKQIILTSDKYPNEIEGLEERLVSRFGYGLTVSVDMPDLETRIAILLKKAHDLGQKLPNETAAFIAENVRTNVRELEGALNRVLTTSKFNHKDPTIEVAQACLRDVIKIQEKKVKIDNIQKVVADFYRIRVKDLTSNQRSRNIARPRQIAMSLARELTSHSLPEIGNAFGGRDHTTVMHAVKAITKLRQSNTSISDDYELLLDKISR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMBP_RAT
Sequence: FVVFILADPARYFQFYFPXFFQHR
What is the function of this protein?
May mediate relaxation of depolarized colon tonus.  It binds iodocyanopindolol and SM-11044.
What are the official names of this protein?
SM-11044-binding protein.
Protein: IOLX_BACSU
Sequence: MEHQVRCAVLGLGRLGYYHAKNLVTSVPGAKLVCVGDPLKGRAEQVARELGIEKWSEDPYEVLEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSLEESKAASEKVKETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPAEFIKHSGGIFIDCSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEFDSGAAGDVEASRTSPYGHDIRAEVIGTEGSIFIGTLRHQHVTILSAKGSSFDIIPDFQTRFHEAYCLELQHFAECVRNGKTPIVTDIDATINLEVGIAATNSFRNGMPVQLDVKRAYTGM
What is the function of this protein?
Catalyzes the reversible NAD(+)-dependent oxidation of scyllo-inositol (SI) to 2,4,6/3,5-pentahydroxycyclohexanone (scyllo-inosose or SIS).  Is required for SI catabolism that allows B. subtilis to utilize SI as the sole carbon source for growth.  Cannot use NADP(+) instead of NAD(+).
What are the official names of this protein?
scyllo-inositol 2-dehydrogenase (NAD(+)).
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: GYRB_STRCO
Sequence: MADSGNPNENNPSTDTGVNDAVSTSHGDASASYDASAITVLEGLDAVRKRPGMYIGSTGERGLHHLVQEVVDNSVDEALAGHADTIDVTILPDGGVRVVDNGRGIPVGIVPSEGKPAVEVVLTVLHAGGKFGGGGYAVSGGLHGVGVSVVNALSTRVAVEVKTDGYRWTQEYKLGVPTASLARHEATEETGTTVTFWADGDIFETTDYSFETLSRRFQEMAFLNKGLKINLTDERESAKATAGADEAGEDEKHEVKSVSYHYEGGIVDFVTYLNSRKGELVHPTVIDLEAEDKDKSLSLEVAMQWNGGYTEGVYSFANIIHTHEGGTHEEGFRAALTSLINKYARDKKLLREKDDNLTGDDIREGLTAIISVKLAEPQFEGQTKTKLGNTEVKTFVQKVVYEHLTDWLDRNPNEAADIIRKGIQAAHARVAARKARDLTRRKGLLESASLPGKLSDCQSNDPTKCEIFIVEGDSAGGSAKSGRNPQYQAILPIRGKILNVEKARIDRILQNQEIQAMISAFGTGVHEDFDIEKLRYHKIILMADADVDGQHINTLLLTFLFRFMRPLVESGHVYLSRPPLYKIKWGRDDFEYAYSDRERDALIEMGRQAGKRIREDSVQRFKGLGEMNAEELRITTMDQEHRVLGQVTLDDAAQADDLFSVLMGEDVEARRAFIQRNAKDVRFLDI
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y939_STAAM
Sequence: MNPIVEFCLSNMAKGGDYVFNQLENDPDVDVLEYGCLTHCGICSAGLYALVNGDIVEGDSPEELLQNIYAHIKETWIF
What are the official names of this protein?
UPF0349 protein SAV0939.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: VIF_HV190
Sequence: MENRWQVMIVWQVDRMRINTWKSLVKYHMHISRKARGWFYRHHFESTHPRISSEVHIPLGEARLVITTYWGLNTGEREWHLGQGVSIEWRLKRYSTQVEPGLADQLIHMHYFDCFSESAIRKAILGRVVRPRCNYPAGHKQVGTLQYLALTALVAPKKIKPPLPSVRKLVEDRWNKPQKTRGHRGSHTMNGH
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: GATC_PROMM
Sequence: MSKITAKDVRKVAQLARLDLPDDQIATYTEQLERILAYVAQLEEIDTTNVKPTTRAVEVVNVTRTDEVSETPVREELLNLAPQREGDFFRVPKILAE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: HSLU_SHEB8
Sequence: MSEMTPREIVHELDAHIIGQQKAKRSVAVALRNRWRRMQLDADFRQEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVEQIIRDLTDIAIKLTREQQMGKCRQRAEEHAEERILDALLPKPKNDWESTETDSSSNTRQVFRKKLREGQLDDKEIDIDVAQPQIGVEIMSPPGMEEMTNQLQSLFKNMGQAPAKRRKMKIKEAFKLLIEEEAAKLVNQEDLKEQAIEMVEQHGIVFLDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVTTKHGMVKTDHILFIASGAFQMSKPSDLIPELQGRLPIRVELDALSADDFKRILTEPHASLTEQYIALMNTEGVKVEFSESGIDSIAKAAWQVNERTENIGARRLHTVMEKLMEDISYEASEKSGSAFVIDADYVSAHLDNLVQDEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_TAV
Sequence: MSTFSLENCLNGSYGVDTPEEVTFIRRRDANPSAFHGEETVPSNTTEVHSESVSYSSDFEGYSCDSDFTGDNQYSSFDGADSLLLSYDIDEYIDLSESELRVLFDEMVQPIHFGMVLSPTFSRNRFLSCLSLAKSVVVAPLYDPERTLRPFPELVKNLYSGVHDIYLSDSEEAAISSVTDTIEGYTFSPRDVVDNYEPPPLCSVCGLIAYQCPHYDINSLRKNCAEMTIAHDYPIEGLCGLIDDATLLKNLGSFLLPIQCEYTKLPEPTLITPPELTRPTDRVTVDLLQAICDSTLPTHVCYDDTYHQTFIENADYSVDIDRVRLKQSDLLAKVIDEGHLKPVLNTGSGQKRIGTTREVLCAIKKRNADVPELCGSVNLKRLSDDVAECFMLSFMNGDKLCSSNFINIVSDFHAYMSKWQSVLSYDDLPDLNAENLQFYEHMVKSDVKPSVTDTLNIDRPLPATITFHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGKISSLEIKDFSVLNKFCLEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGNTLVTMSMFAWCYDTSQFDKLIFSGDDSLGFSIKAPVGDPSLFTSLFNMEAKVMEPSVPYICSKFLLTDDFGNTFSVPDPLREIQRLGSKKIPLDEDDRSLHAHFMSFVDRLKFLNHMNQTSMTQLSLFYEMKYRKSGDDILLVLGAFNKYTANFNAYKELYYSEKQQCALINSFSISDLIVGRGKSSKASRRKAVESNGKHRDPSTRDHSKVGTDESKETSTEETTQTEPQGAGSQKSK
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 3 RNA segments, RNA1, RNA2 and RNA3.
What are the official names of this protein?
RNA-directed RNA polymerase 2a, protein 2a.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: FCTA_ECO81
Sequence: MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGFGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPLVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQELGYSDDEIAAMKQNHAI
What is the function of this protein?
Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR).  Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity).
What are the official names of this protein?
Formyl-CoA:oxalate CoA-transferase, FCOCT, Formyl-coenzyme A transferase, Formyl-CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. Frc subfamily.
Protein: DHSD_CAEBR
Sequence: MAASLRHMAHFQKALLVAKTAPRLSTIVRATSTLNDGASKVPDHSMHFKLERLWAVGMLPILPASYFIHGPVMDAVLTVALTLHIHWGIHGVVYDYARPYVIGEAAAKAAHIGVYLITGLLLAGLLHFNTNDVGITKAFELVFSL
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial, Succinate dehydrogenase complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the CybS family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TYW32_PYRFU
Sequence: MKAKREALLSLFQAIKENKVDEDIVELLLLINSIKGVYTTSSCSGRIGIIEEPSLGAKPLSRWLIKVHRPIKFEEAKKALKNAQKGLIFLKSQPPIFHVVTESLELARKIHEIGLSSGFKYTTYKVISRRYLVEINGTEYLTVPLGKDGKVFVTDEYLEFVIEIGNQMLMRGKSRLPRLREKFEELKEEVGEDPLFTTLSTEKLSL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway.  Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
What are the official names of this protein?
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 2, tRNA wyosine derivatives biosynthesis protein Taw3 2.
What is the protein family that this protein belongs to?
Belongs to the TYW3 family.
Protein: GLNA1_ALNGL
Sequence: MSLLSDLINLNLSDATDKVIAEYIWIGGSGTDLRSKARTLTGPVNHPSKLPKWNYDGSSTGQAPGEDSEVIYILRQFFKDPFRRGNNILVICDTYTPAGEPIPTNKRHGAAKIFSHPEVVAEVPWYGIEQEYTLLQKDVKWPLGWPVGGYPGPQGPYYCGIGADKAWGRDIVDAHYKACLYAGINISGINGEVMPGQWEFQVGPSVGISAGDEVWAARYILERITEIAGVVLSLDPKPIQGDWNGAGAHTNYSTKSMRNNGGYEIIKKAIEKLGLRHKEHIAAYGEGNERRLTGRHETADINTFKWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYVVTSMIAETTLLWKP
What are the official names of this protein?
Glutamine synthetase, GS(1), Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_LEPBL
Sequence: MAKEEAITVDGTVLEPLPNAMFRVELENGHKVLAHISGKMRMHYIRILPGDKVTVELSPYDLSKGRITYRKK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_ESCF3
Sequence: MFTINAEVRNEQGKGASRRLRTANKFPAIIYGGNEAPLAVALDHDKVMNMQVKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLLHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: YMP6_CAEEL
Sequence: MHPDQKKTFKEKNDIRKKLFNSTKEERLDWRKMKDEKKRKNEEKIIKEAEEAKKAKIEKVDHTPPFTISIAVPGQFLNNAQSAELRTYMAGQIARAATLYRVDEIIIYDESCRMTDEAVNAYYNGTWQGNLIPAETNYEGCFYLAKILEYLECPQYLRKDLFPIQKPLKNAGLLNPLDAQHHLKYDEKTLRFREGVVLKKRSKDGRGPICNIGLEKEFEIDSDAVQLPPYTRVTVEIKNLTEQCKLYRGSITSGATVTRETGLYWGYSVRLMTGLQKVLQAKKFDIVAGVSPRGKLASQMDVCILNKPKILLVFGGVAGVDAAVESEELAEWRRAEDAFDVLIRTTSLSNGSRSERVEENVLSVLAQVQCHLETLNAL
What are the official names of this protein?
Putative methyltransferase B0361.6.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily.
Protein: SSRP_YERPS
Sequence: MTKKKAYKPGSATIAQNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVMFKNGEAFLFGATITPLNVASTHVVCEPMRTRKLLLNKRELDSLFGRVNREGYTVVALSMYWKNAWVKVKIGVAKGKKDNDKRDDIRDREWKLDKARIMKHANR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RTL4_HUMAN
Sequence: MEKCTKSSSTMQVEPSFLQAENLILRLQMQHPTTENTAKRGQVMPALATTVMPVPYSLEHLTQFHGDPANCSEFLTQVTTYLTALQISNPANDAQIKLFFDYLSQQLESCGIISGPDKSTLLKQYENLILEFQQSFGKPTKQEINPLMNAKFDKGDNSSQQDPATFHLLAQNLICNETNQSGQFEKALADPNQDEESVTDMMDNLPDLITQCIQLDKKHSDRPELLQSETQLPLLASLIQHQALFSPTDPPPKKGPIQLREGQLPLTPAKRARQQETQLCLYCSQSGHFTRDCLAKRSRAPATTNNTAHQ
What is the function of this protein?
Involved in cognitive function in the brain, possibly via the noradrenergic system.
What are the official names of this protein?
Retrotransposon Gag-like protein 4, Mammalian retrotransposon-derived protein 4, Zinc finger CCHC domain-containing protein 16.