PharMolix/UniProtQA huggingface dataset:
Protein: GLBBP_PSEAE
Sequence: MNRLIRSLCLACAGLFAAGLAQAETLRIGGKTFTEQRILTAITAQFLQKRGYDVTVTTGLGSTLARAAQESGQLDIVWEYTGSSLIVYNHIDEKLDAAASYRRVKQLDEAQGLVWLKPTRFNNTYALAMPEEQAEHLGIQSVSDLARVLAEQQEAEPGSTHLFAMDPEFAGRPDGLGPMSELYGLHFTRNDIRQMDAGLVYTALKNRQVFLGLVYTTDGRLKDFKLRVLKDDKQYFPFYNAAPVVRKEVMQRHPEFATLFDPIIERLDDATMQALNARVDIEQQTPQKVAADFLREHHLLDDGQAGQGGSQ
What is the function of this protein?
Binds glycine-betaine.
What are the official names of this protein?
Glycine-betaine-binding protein.
What is the protein family that this protein belongs to?
Belongs to the OsmX family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1002_RHIME
Sequence: MAGRWTSLVDEAAAPWLPRGGLGSAIARHDFRRLRAVAAVSLTALPIVPLALTLALPVSAALPAGAALWASASLLAAAAAIAGGREFPTDGEVEFAPAPELPDLNAAYDLFAGLVTVHDTRGHVLSVHGRDASEYLKLMRDPHGRGFIEQIHVSDRIAFLRAIDSLRLDSERSAVDIRLERTSADGPQFAHIYCEMTPLRDAEGNLLAIVAQSRDVSEEARLQAEAAAKAAHAESANDAKTRFLAAVSHELRTPLNAILGFSDVLAGEYFGKLENDRQREYVSLIHQSGTHLLSVVNTMLDMSKIEAGRYELLLEPFRVAEAIAACEAMLSHQAREKGVRLTSRVTRSVGEINADQRAFQQILINLIGNAIKFTDRGGLVTVDAALEGNMLKLTVSDTGIGIAADKLQMLGQPFVQIQNDYTRRYEGTGLGLSLVKGLAELHGGDVSIRSAEGEGTVIVVTIPSDASGAAERQCADAPVTVEFPPRLKQHADGKREAGVPALSEALHTGEIGREGGHGAAQAKTA
What are the official names of this protein?
Uncharacterized sensor-like histidine kinase R01002.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS7_NITMU
Sequence: MRHAQVNRNTLETRINIKVNLDGSGKAVLATGVPFLDHMLDQVARHGMIDLEVSAEGDLHIDAHHTVEDIGITFGQAFTQAVGTKSGLRRYGHSYVPLDEALSRVVIDLSGRPGMEFNVEFVRARIGEFDVDLISEFFRGFVNHAMVTLHIDNLSGTNAHHQAETIFKAFGRALRMAVEADPRAAGAIPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y619_STRA5
Sequence: MSQEKLKSKLDQAKGGAKEGFGKITGDKELEAKGFIEKTIAKGKELADDAKDAVEGAVDAVKEKLK
What are the official names of this protein?
UPF0337 protein SAG0619.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: PELO_META3
Sequence: MKIIKEIPEKNIIKVMPENLDDLWHLSNIILKNNAVSAMTERRTEDKGDKLRADRGTKRRVYLGVKAEKIKFDENTNRLRVSGPIIHGPEDVPIGSYHTIDIEPLKDVSIQKNWKKWDLQRLKDAENSAKKPKIIVVIMDDSDATVFIIRDYGVKEIGHIKSRLSKKLDYKRQDQENINYYNEILEVMSPYEGKILVAGPGFTKNNFQKYLSEKHKDMLQRVVFESTNHTGRLGLAEVLKSGIVDRIYGEARLSKETQLVNKLLEEISKKGLAVYGVDDVKNALNYSAIETLLITDEFLRKNRRILEDLINSVEAIGGSSIIISTEYDVGKQLKALGGIGGLLRFPIE
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPB_LATSS
Sequence: MNHLAEIESLLYVAGDEGITLQHIARLIMLDEAAVRQLLTKLAKRYQEDEQSGLNLIQAADCYKLVTKKAYAGLLKAYFDGPVSTSISQAALEVLAIIVYRQPLTRIEIDEVRGVQSSGAIQTLLARQLIVEKGRKDAPGRPILYGTSDYFLDYFGLGSLKELPELEQMTLTDDTAESDNDSADLYYRQFEQTLNETGPETAPKGEQ
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: NTPPA_BACAC
Sequence: MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNKAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_CHLPN
Sequence: MTADEVGKNSFAKKEEQVLKFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLLASTIKDVVGRYATMDGYYVPRRFGWDCHGVPVEYEVEKSLSLTAPGAIEDFGIASFNEECRKIVFRYVHEWEYYINRIGRWVDFSSTWKTMDASFMESVWWVFQSLYNQGLVYEGTKVVPFSTALGTPLSNFEASQNYKEVDDPSLVVRMPLQNDSASLLVWTTTPWTLPSNMAIAVGETLVYVRIQDKKSGEQWILSQGCVSRWFSNPEEFVILESFSGKDLVGRTYEPPFTFFQSKREEGAFRVIAASFVEESEGTGVVHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQGQYIKHADKEIIKFLKKEGRIFYHGTVKHRYPFCWRTDTPLIYKAVNSWFVAVEKIKDKMLRANSSIHWVPEHIQEGRFGKWLEGARDWAISRNRYWGTPIPIWKSADGEILVVGSIRELEELTGTQITDIHRHFIDDLNIVKDGKPFHRIPYVFDCWFDSGAMPYAQNHYPFENQKETEEAFPADFIAEGLDQTRGWFYTLTVISAILFDRPAFRNAIVNGIILAEDGNKMSKRLNNYPSPKYVLDTYGADALRLYLLHSVVVKAEDLRFSDKGIEGVLKQILLPLTNVLSFFNTYAELYGFDPKSQDIEPAYTEIDQWILSNLYSVVGKVRESMSQYHLNFAVEPFVTFIDDLTNWYIRRCRRRFWEAEDTPDRRAAFSTLYEVLTVFCKVIAPFVPFLAEDIYQKLKLEKEPESVHLCDFPQVEMDKILPDLEKRMHDIREIVGLGHSLRKEHKLKVRQPLANFYVVGSKDRLSLLKTFEGLIAEELNVKNVIFYEEAPSFIYTTVKPNFRMLGKKVGSKMKEVQKALSELPNNAIDKLIQEETWVLTIDDREIALDGDDVVICRHTDPGYIARSSALFSVILDCQLREPLIVEGIARELVNKINTMRRNQQLHVSDRIALRIKTTEAVHRAFLDYENYICEETLIIAYDFTQDSDFQGENWDINGHATQIEITVSSIDS
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_LISMF
Sequence: MAKKSMIAKQKRTPKYAVQAYTRCERCGRPHSVIRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: FBL39_ARATH
Sequence: MNAKDVISRLPDEVLGRILSLISTKEAVSTSVLSKRWKNMFVLVSNLDIDDRQSVPKTKQNRIEIHRNYMAFVDKLLDTQRGSSIKKLTLKSHVGVRGGTDSSRIQSWICNVLDHGVMDLDVFITLKGKSPPVPAMIFKSKTLVKLRVGRGFTIKLSQDVSLPLLRTLCLDSVNFVGGHNVVGTLISRCPVLEELVVEERRCVDWTCSVSSPSLKRLHIRFDRKFTSISLDAPNLIYYKHSGYVLGKYPNVKLDSLIEARLNLRMDETRMVGVRNGSLGSIPADMRNLINGIRNVRILHLSSHTLELLYFSCKEMPLFDSLVSLSIGNDKARGWQMLPLLIKNSPNLETLIFMGLDHYITNRCGDVCVCYDTDESITSCLSSSQVKVLEILSYQGTTRELNQMKHFLEKLPCLELVKICVVNNSNNLQTTMEMRNLMMLPRASSKCKIQVKVLTKNN
What are the official names of this protein?
F-box/LRR-repeat protein At2g42730.
Protein: RCNR_SALPB
Sequence: MSHTIRDKQKLKARTSKIQGQVIALKKMLDEPHECAAVLQQIAAIRGAVNGLMREVIKGHLTEHIVHQSDEARREEDLDVILKVLDSYIK
What is the function of this protein?
Repressor of rcnA expression.  Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt.  In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity).
What are the official names of this protein?
Transcriptional repressor RcnR.
What is the protein family that this protein belongs to?
Belongs to the FrmR/RcnR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_THEP1
Sequence: MLVNTIRQKVSEVISKVYDSEIEFEIEIPPKKEFGDLSTNAAMKLAKTLKKNPREIAQEIVKSLDEDPSFDRIEIMGPGFINFFLSNELLRGVVKTVLERKDEYGRENTGNGVKIQFEYGSANPTGPFTVGHGRQIIIGDVLSEVFKELGYDVTREMYINDAGKQIKLLAQSLWARYNQLLGVEKEIPEGGYRGEYLVDIARDLVSEIGDKYKDLWNEEVEELFKQTALNRILSSMKDTLEKIGSSFDVYFSEKSLIEDGTVEEVLKLLKDRDVVYEKDGAVWLKVSAFIDEEDKVLVRSDGTYTYFMTDIAYHYKKYKRGFRKVYDIWGSDHHGHIPRMKAAMKALDIPDDFFNVILHQFVTLKRDDEIVRMSTRAGEFVTLDELLDEVGRDAVRYFFAMVDPNTHMVFDIDLAKAKSMDNPVYYVQYAHARIYNLFSNAEKKGVKFEEGKHLELLGNEEERVLMRNLGMFNTVLKEVAQMFAPNRLTNYLQSLAESFHAFYTKHVIVDPENPELSNARLNLALATGIVLRKGLKLIGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_PSEPW
Sequence: MSQPLTVDCPTCGAPVEWDAKNAFRPFCSDRCKLIDLGAWAAEEHKIAGSQESEDELYSGDLEPRH
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: HAL1_HALST
Sequence: GMWSKILGHLIR
What is the function of this protein?
Short linear cationic amphipathic alpha-helical antimicrobial peptide (AMP) with potent activity against both Gram-positive and Gram-negative bacteria, and moderate activity against the yeast C. albicans (PubMed:20198492, Ref. 2).  Has been tested on B. subtilis (MIC=0. 8 uM), S. aureus (MIC=7. 7 uM), E. coli (MIC=3. 8 uM), P. aeruginosa (MIC=45 uM), and the yeast C. albicans (MIC=6. 2 uM) (PubMed:20198492, Ref. 2).  Has also noticeable hemolytic activity (LC(50)=102 uM on human erythrocytes, and 82 uM on rat cells), indicating it cannot be considered for therapeutic application (PubMed:20198492).  Interacts more strongly with anionic membranes compared to the zwitterionic ones because of the electrostatic contribution (PubMed:32336099).  Interaction with anionic membranes is accompanied by structuring of the peptide as an alpha-helix and deep insertion into the membrane causing substantial membrane permeabilization at very low peptide/lipid molar ratios (PubMed:32336099).  In the context of inflammation and cancer tests, is weakly cytotoxic to normal cells, induces calcium signaling but does not impact cAMP production (PubMed:22100226, PubMed:36548715).  In addition, prevents LPS-induced nitric oxid (NO) synthesis but does not affect the IP3 signaling and pro-inflammatory activation of endothelial cells (PubMed:36548715).  Is cytotoxic towards cancer cells (HeLa S3 (IC(50)=11 uM), CRC SW 480 (IC(50)=44 uM), CCRF-CEM T (IC(50)=49 uM)), but does not show significant antiproliferative activity on the breast cancer cell line MDA-MB-231 (PubMed:22100226, PubMed:36548715).
What are the official names of this protein?
Halictine-1, HAL-1, Halictin 1, Halictine I.
What is the protein family that this protein belongs to?
Belongs to the lasioglossin-like family.
Protein: TRPA_NITHX
Sequence: MTTRIDTRFAELKKQGRSAFVTFLMGGDPDPATSLAIIKALPKAGADIIEIGMPFTDPMADGPAVQAAGRRALNAGMTVTRTLQMIHDFRKGEGSTPVVLMGYYNPIYIYGVEKFLTDAKAAGVDGLIVVDLPPEEDSELCIPAMKAGLNFIRLATPTTDDKRLPAVLANTSGFVYYVSITGITGSAAADSTAVGAAVARIKRHTTLPVCVGFGIRTADAARGIAERSDGAVVGSALVDALSGSLDAEGKATAKTVNAVADLAAALAAGVRSARQAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL27_ACTP2
Sequence: MATKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGNNVGMGKDHTLFATADGKVKFEVKGEKNRKYVSIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: IDH3A_MESAU
Sequence: MRPGVAAVAAVRIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRRIAEFAFEYARDMANPTALLLSAVMMLRCSDFTEEICRR
What is the function of this protein?
Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitric dehydrogenase subunit alpha, NAD(+)-specific ICDH subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RECA_SALHS
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPVYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGDNVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYNGEKIGQGKANATTWLKENPATAKEIEKRVRELLLSNQNATPDFAVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y43_BPT7
Sequence: MFKLIKKLGQLLVRMYNVEAKRLNDEARKEATQSRALAIRSNELADSASTKVTEAARVANQAQQLSKFFE
What are the official names of this protein?
Protein 4.3, Gene product 4.3, Gp4.3.
Protein: KTHY_HERAR
Sequence: MTKAKFITFEGIDGAGKSTHLSFVADLLRASKKNVVVTREPGGTSLGEALRTILLHEKMHLETEALLMFAARREHIAQLIEPALARGDWVISDRFTDATFAYQGGGRKLDRQKLSVLEQWVHPHLQPDLTLLFDVPLDVARARLDATRTLDKFEQEQADFFAATRAEYLRRAAEFPQRFRIIDSTQAIATIQEQLRDIIAGLAP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NEK5_ORYSJ
Sequence: MDSRMDQYEVMEQIGRGAFGAAILVNHKTEKKKYVLKKIRLARQTERCRKSAHQEMALIARLQHPYIVEFKEAWVEKGCYVCIVTGYCEGGDMAELMKKANGTYFPEEKLLKWFAQLALAVDYLHSNFVLHRDLKCSNIFLTKDQDIRLGDFGLAKTLKADDLTSSVVGTPNYMCPELLADIPYGFKSDIWSLGCCMYEMAAHRPAFKAFDMAGLISKINRSSIGPLPPCYSPSMKSLIKSMLRKSPEHRPTASEILKSPYLQPYVNQYRPFADISHPIHSLEKPITSSRSSQKSMSGSQCSSISGSDIDSIQSSERNTSGPSTSSNNTIDTEGAEATDHVSVKNCSRSDDVKSNKETVGPELERQDSSKSIHVDQRPRNEIKQPKIIKKILTTLREESKLRQNNSPIRASRVKLNSPSNREQLSDDSKHSSDISSSSKSSEVTSRESAKVICEPVKRAQASPPLKHLSPIVEHSPKAKIKQDEPLQPDPAKQAMEDVDAAVGKVKNRTPPSYSRRLSIPPRRPLGAESPLHADTKRAHNKVIKERAKSPCRPVHGPDNDIIEPPGFPMAPPSPLGGVQMKVGNARAKSAPPRAVSIKEDSSDCSSSTIAYAENTELSEPSKQDSSAQLVSSCKCSIPDAAIQKHDLTAMPSSELNTTNFQKSMASNDDVCENLALEPSSDISEQVSIFKDNVPCSKISQSTANAIVQNDEDKFTVQELLSSVADIAPFVSTKNFALEKGSPPIQSLERTSSPHLNPPIEDVIHVIRHSSFRVCGEQAVAENAEMGVQSSDVGKLLNVVREEVDSRSIPSNNLVPHRLPDCAAPKPNISETNTISSKTACSDVVKFLTVPEVNSTTTAINNGFKEEASPTKEILDVKSFRQRAEALEGLLELSADLLQHNRLEELAVVLKPFGKDKVSPRETAIWLAKSFKGMMNDEASRSSM
What is the function of this protein?
May be involved in plant development processes.
What are the official names of this protein?
Serine/threonine-protein kinase Nek5, NimA-related protein kinase 5, OsNek5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Protein: MKAR_LACBS
Sequence: MDVFNVQELSFSLVRDQPYLSAFLLVMGSIGVGRVIYQTLSVFLQTFILPGTNLRKFGAKKGAWAVVTGATDGIGREFSLQLAKAGFHVFLVARNEALLASTAAEIEQKYGVSTATHSIDFSKADKSAYNSLGSSLGSVDVGVLVNNVGKSHAMPAYFVDTPEEEMSDIVSINVQATLQVTHSVLPGMVQRKRGLILNVGSFAGAVPSPMLATYSGTKAFLTTFSSALGEEVRKDNITVEHLNTYFVVSKLSKIRKASALIPKPDAYVRSVLSKIGLPCGASYSGRPNTSTPFWSHALLDYGLTLIGLQSAFISYTHGLHKDIRRRALRKMERDAKLQ
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RIMO_CROS8
Sequence: MSNVMQQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPRYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLQHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLDSRPIGDVLAEAKRLVEAGVKELLVISQDTSAYGVDVKHRTGFWNGSPVKTSMVSLCEQLAKLGVWVRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEDDFQMLLDFLKEARLDRVGCFKYSPVEGATANDLPDQVPEEVKEERWNRFMALQQQISAERLQEKVGREILVIIDEVDEEGAIGRSMADAPEIDGAVYLNGETKLKPGDVVRVKVENADEYDLWGSLV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_CHLTR
Sequence: MYEYIKGTLTHINESYVVIESFGIGYAIMLSERFLVDLRAFMHQEVLIYVHSVIRETEHVLYGFSSRAERECFRLLISFSGIGPKTGLSILNMFPLQELCSIARLENVKAIASVPGIGKKTAEKLMVDLKQKLPTLMPLYLEEPVVPSSTANSSFKEGIGALMNLGFSRLAADRMMTEAVKELSEEASVAELLPIALRKS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: FABR_YERPG
Sequence: MGVRAQQKERTRRSLIEAAFSQLSAERSFASLSLREVSREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRSFTEAQAEAMVTIVFSAGAEVLDVDIEQRRQLEERLVLQLRMISKGAYYWYRREQEKLAASRVE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_HYPNA
Sequence: MDISPAEISGILKSQIENFGVEAEVSDVGQVLSVGDGIARVYGLDSVQAGELVEFNGGIKGMALNLEKDNVGVVIFGEDRSIKEGDTVKRTSEIVAAPVGKALLGRVVNALGEPIDGKGPLKDVAARSQVDVKAPGIIPRKSVHEPMMTGIKAIDGMIPVGRGQRELIIGDRQTGKTAICIDTILNQKPTNDAAKSDKDKLFCVYVAIGQKRSTVAQVVKVLEERGALDYTIVVSATASESAPLQYLAPFTGCTMGEWFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDNGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFNSGIRPAVNVGLSVSRVGSAAQTKAMKKVAGSMKGELAQYREMAAFAKFGSDLDAATQRLLNRGARLTELLKQPQYSPLLMEEQVVIIYAGTRGYLDKVALKDVTRYEKELLVHMRGAKKELLAKLREKKELTSEIEDEIKKALDDFTSKFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAAF1_CHLRE
Sequence: MCACMTKEALLEVCKQNGLYRTASLNDKLYCNFKGFSQIACLEDYVNLKALFLEGNVLETLEGLPPLADLKCLYVQQNCIWKISGLEAVPGLDTLNISNNQLTKLEGLACCPALRTLIATHNHLVTLDSVAHLAECKALQTLDLQNNELEDPGIVDILKQIPDLRCLYLKGNPVVSNIKNYRKVLVTSIPSLTYLDDRPVFDNERKIAQAWLEGGLEGERAMRNQLKEEEEERSRKNHEFMMQMRAAGWRERRKRMGLPDGDTDPALDDMSDGEYEFDEEPEELVEARQRLAAYTARPGEEEPAELASARQGLARDGKPIQEGAWGSGAAAESDSAIYLQSVKAAQAELDVVRQQQPRQLPTAQVLIEELDEPCGGKAPAADEGSTPPALSPMTSPSGSEGQGGEGVAAAKKGAASGAAEGISAAVDINDLD
What is the function of this protein?
Cilium-specific protein required for cilia structures.  Axonemal dynein-associated protein that participates in a structural link between inner and outer row dyneins.
What are the official names of this protein?
Leucine-rich repeat-containing protein ODA7, Dynein assembly factor 1, axonemal homolog, Leucine-rich repeat-containing protein 50 homolog, Outer row dynein-assembly protein 7.
What is the protein family that this protein belongs to?
Belongs to the DNAAF1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: GCSPA_STAAC
Sequence: MSHRYIPLTEKDKQEMLQTIGAKSIGELFGDVPSDILLNRDLNIAEGEAETTLLRRLNRIASKNITKETHTSFLGAGVYDHYAPSVVDAMISRSEFYTAYTPYQPEISQGELQAIFEFQTLICELTDMDVANSSMYDGMTSFAEACILAFSQTKKNKIVVSKGLHYQALQVLHTYAKTRKEFEVVEIDLDGTVTDLKKLEAAVDDETAAVAVQYPNFYGSIEDLKKIHSFIEDKKALFIVYANPLALGLLTPPGSFGADIVVGDTQPFGIPAQFGGPHCGYFATTKKLMRKVPGRLVGQTQDDEGNRGFVLTLQAREQHIRRDKATSNICSNQALNALASSIAMSALGKQGIYDIAVQNIEHANYAKQQFIKKGFEVLDGTSFNEFVVKFDKPIQQVNEELVKYNIIGGFDLGVVSDDFKNHMLIAVTELRTKDEIDTFVEKAGELND
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.