PharMolix/UniProtQA huggingface dataset:
Protein: EID3_BOVIN
Sequence: MADENGSLREAGAGGKTRAQAVVTIPSSAYFLKQVEEEEEVEALKVEVAAASDTESDTSSDDLSCGKADIDPSLLERVDEEKCRSIRKQYRQLIYTVQQNRDDIVNTASDSLTEALEEANVLFDAVSRTREAALDSQFLVLASDLGKEKAKHLNSDMNFFNQVAFCDFLFIFVGLNWMEDDERDPLNNCDDNIALSFWETVQKEATSCISQAETFHFLFGSFKPESAARKPRRNHRRKVQKMEENGVMPTKLRKLDLSGNQEATEKEVERILGLLQTYFRKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIIRDGFARIRLDQDRLPILEPININLAGEGNDPSFHSRKQGVISLSLQDWKNIVAAFEISEAMITNSY
What is the function of this protein?
Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation.  May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors (By similarity).
What are the official names of this protein?
EP300-interacting inhibitor of differentiation 3, EID-3, EID-1-like inhibitor of differentiation 3, Non-structural maintenance of chromosomes element 4 homolog B, NS4EB, Non-SMC element 4 homolog B.
What is the protein family that this protein belongs to?
Belongs to the NSE4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome, telomere. Note=May shuttle between nucleus and cytoplasm.
Protein: BION_RHOCB
Sequence: MLSLALPCRSWAHRLPAALKFGLLAVAMIALMRIGSLAGQGAAVLVVAALTASLGRKAIRQSLVTLRPLVWIVAVILIWDSLQGAVAQGVLFGLRVLAMVGLANAVTLTTPLPEIVALIERLAQPLARFGISPRIPAISVALVIRFVPVLRARHDTLAEAWRARSARKPRGKLLAPLTFSLLDDADHMADALRARGGLALPRKGRDTVGT
What is the function of this protein?
Probably involved in biotin uptake, although complementation experiments in E. coli do not indicate a clear role.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein BioN, ECF transporter T component BioN.
What is the protein family that this protein belongs to?
Belongs to the CbiQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FADH_ASPOR
Sequence: MRHVLNKEQLLMVKQAAIAWAAAEPLSVENVEVAPPKAHEVRIKILHTGVCHTDAYTLSGKDPEGAFPVILGHEGAGIVESVGEGVTNVKVGDYVIALYTPECGECKFCRSGKTNLCGKIRATQGRGVMPDGTTRFKARGKDLLHFMGCSTFSEYTVVADISVVAVTPSCPTDRSCLLGCGITTGYGAATVTANITEGSNVAVFGAGCVGLSIVQGAVKKKAGKIIVVDINDGKEAWAYKFGATHFLNPARLRKTVQDELIDMTDGGCDYTFDCTGNVSVMRAALEACHKGWGESIVIGVAAAGQEITTRPFQLVTGRVWRGCAFGGVKGRSQLPGLVEDYLNGDLKIDEFITHRETLANINTAFEQMKQGDCIRCVVDMVVS
What is the function of this protein?
Confers resistance to formaldehyde.
What are the official names of this protein?
S-(hydroxymethyl)glutathione dehydrogenase, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, FLD, GSH-FDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Protein: YJJB_KLEP7
Sequence: MGIISFIFALAEDMLLAAIPAVGFAMVFNVPQRALRWCALLGAIGHGSRMIMMSAGFNIEWATFLAALLVGSIGIQWSRWYLAHPKIFTVAAVIPMFPGISAYTAMISAVKISHFGYSEEMMILLLSNFLKASSIVGALSIGLSIPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPP_CLOAB
Sequence: MRMNLKKLIINSLFLAVGVVLNQITPPILFGMKPDFSLAMLFIIILLNDDYKTCISTGVVAGLLAAAVTTFPGGQLPNIIDRIVTTSLVFIALRPFKDKINDKIHMIITTIVGTIISGSVFLGSALIIVGLPASFKALFITVVLPATIINAIVGTIIFVAVKKSMRVVFRQ
What is the function of this protein?
Probably involved in tryptophan uptake.
What are the official names of this protein?
Probable tryptophan transport protein.
What is the protein family that this protein belongs to?
Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. TrpP subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VPRE2_MOUSE
Sequence: MAWTSVLLMLLAHLTGCGPQPMVHQPPSASSSLGATIRLSCTLSNDHNIGIYSIYWYQQRPGHPPRFLLRYFSHSDKHQGPDIPPRFSGSKDTARNLGYLSISELQPEDEAVYYCAVGLRSHEKKRMEREWEGEKSYTDLGS
What is the function of this protein?
Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells.  This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation.
What are the official names of this protein?
Immunoglobulin omega chain, Protein VPreB2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
Protein: GLYA_CLOBJ
Sequence: MDFTNLKNTDPELLDMIKKEEERQEYNIELIASENFTSLSVMEAMGSLLTNKYAEGYPHKRYYGGCEFVDEVEDLARERLKKLFAAEHANVQPHSGSQANMAVYMSVLQTGDTILGMDLSHGGHLTHGSPVNFSGKLYNFISYGVDKETETIDYEKLKKIALENRPKMIVSGASAYPRIIDFQKIREICDEIDAYMMVDMAHIAGLVATGLHPSPVPYADFVTTTTHKTLRGPRGGAILCKEKYAKAVDKAIFPGIQGGPLMHTIAAKAVCFGEALREDYKEYMQQVVKNTKVLGEELKNYGFRLISGGTDNHLLLIDLTNKNITGKDAEKLLDSVGITVNKNTIPFETLSPFITSGIRIGTPAVTTRGFKEEEMKKIAYFMNYSIEHREENLSQIKEQIKEICKKYPLYQNA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_DINSH
Sequence: MLKRSFDKSKLPSRHVTEGPSRAPHRSYYYAMGMTEEEIHQPLVGVATCWNEAAPCNIALSRQAQAVKMGVKQASGTPREFTTITVTDGIAMGHEGMRSSLASREAIADTVELTMRGHCYDAIVGLAGCDKSLPGMMMAMVRLNVPSVFIYGGSILPGRLNGEDVTVQDVFEAVGKHQAGNYTDAELEVLERVACPSAGACGGQFTANTMACVSEAIGLALPNSAGAPAPYESRDQYGEASGRAVMDLIEKGIRARDIVTRKSLENAARIVACTGGSTNAGLHLPAIAHEAGIEFTLQDVCDIFRDTPYFVDLKPGGKYVAKDMYEAGGVPVVMRELRRAGLIHEDCMTVTGYSIGEELDKVTLEADGRVIYPVDTPLSTTGGVVGLEGNLAPEGAIVKIAGMSDDQLVFTGPARVFECEEDAFEAVQNRAYAEGDVFVIRNEGPAGGPGMREMLATTAALSGQGMGKKVALITDGRFSGATRGFCVGHVGPEAAHGGPIAMLKDGDMITIDALKGELSVALSEDELAARKDAWSGPRETIYASGALWKYAQLVGGARLGAVTHPGAKDEKHIYADL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: MDS_PHYTS
Sequence: MAFLKKSLFLVFFLGFVSLSICEEEKRETDEKENEQEDDREERSEEKRLLGMIPVAITAISALSKLG
What is the function of this protein?
Antimicrobial peptide with activity against Gram-positive bacteria S. epidermidis ATCC 12228 (MIC=50 uM) and S. aureus (MIC=64 ug/ml and MBC=128 ug/ml) (PubMed:28469603) (By similarity).  Not active against some Gram-positive bacteria (methicillin-resistant S. aureus (MRSA), E. faecalis), Gram-negative bacterium E. coli ATCC 25922 and fungus C. albicans at concentrations up to 100 uM (PubMed:28469603) (By similarity).  Can only slightly inhibit the formation of biofilm by S. aureus (minimal biofilm inhibitionconcentration MBIC=512 ug/ml, minimal biofilm eradication concentration MBEC>512 ug/ml) (PubMed:28469603).  Has an anti-inflammatory effect, since it inhibits the production of the pro-inflammatory cytokines TNF-alpha and IL-1beta (By similarity).  Has high activity of stimulation of insulin release, which may protect the species from being eaten by predators by causing fatal hypoglycemia (By similarity).  Is not cytotoxic to cancer line cells (By similarity).  Shows very low hemolysis on horse erythrocytes and moderate hemolysis on mouse erythrocytes (PubMed:28469603) (By similarity).
What are the official names of this protein?
Medusin-PT.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Medusin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: SSB_CERS4
Sequence: MAGSVNKVIIIGNLGRDPEVRSFQNGGKVVNLRIATSEQWRDRASGERKERTEWHSVAIFDENLARVAEQYLRKGSTVYIEGQLETRKWQDQSGQDRYSTEVVLRPFRSSLTMLGGRGEGAGAGGGMGGGGYEDRGGPDNYDNYGSGPRGGASSGGAPSGGGRRNDLDDEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: KRAK_DROME
Sequence: MGQTRVAATTAAQSPAAELSPETNGQTEEPLQLLGEDSWEEFSIAVPWGTVEAKWWGSKERQPIIALHGWQDNCGSFDRLCPLLPADTSILAIDLPGHGKSSHYPMGMQYFIFWDGICLIRRIVRKYNWKNVTLLGHSLGGALTFMYAASFPTEVEKLINIDIAGPTVRGTQRMAEGTGRALDKFLDYETLPESKQPCYSYDEMIKLVLDAYDGSVDEPSVRVLMNRGMRHNPSKNGYLFARDLRLKVSLLGMFTAEQTLAYARQIRCRVLNIRGIPGMKFETPQVYADVIATLRENAAKVVYVEVPGTHHLHLVTPDRVAPHIIRFLKEA
What is the function of this protein?
May have a role in detoxification and digestion during embryogenesis and larval development.
What are the official names of this protein?
Probable serine hydrolase, Kraken protein.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: PPE10_MYCMM
Sequence: MTNPHFAWLPPEINSALMFAGPGAGPLLAAAAAWGGLAEELASAVSSFSSVTSELTSGSWLGPSAAAMMAVATQYMAWLGAAAAQAEQAAAQAAVTAGAFESALAATVQPAVVTANRGLMQVLAATNWLGFNTPAIMDIEAAYEQMWALDVAAMAAYHAEASAAASALAPWKQVLRNLGIDIGKNGQINLGFGNSGTGNVGNNNVGNNNWGSGNTGSSNVGTGNTGSSNIGSGNTGNSNVGLGNLGSGNVGFGNTGNGDFGFGLTGDHQFGFGGFNSGSGNVGIGNSGTGNVGFFNSGNGNMGIGNSGSLNSGLGNSGSMSTGFGTASMSSGMWQSMHGSDMASSTSLASSATYATGGTATLSSGILSSALAHTGGLNPALAGGLTPTAATPAAAAPAAAAPVAAAAADAGPVSAGANSGSTAGAGLRSPAAGYSGLYNSANSDAGARSVATREAPANAGAGIPRSSFYPNRETADSEADIQLPLRTE
What is the function of this protein?
Plays a major role in the integrity and stability of the capsule.
What are the official names of this protein?
PPE family protein PPE10.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: LEUC_RHIPU
Sequence: MGRTLYDKVWDDHVVDQQEDGTCLIYIDRHLVHEVTSPQAFEGLRNAGRKVRRPDCTLATVDHNIPTTPRKNFKNVSTFIQEADSRTQCETLEHNVKEFGLTYFGMDDSRQGIVHVIGPEQGFTLPGCTVNCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLLQKKSKNMRVKVDGKLAPGVTSKDIVLHIIGVIGTAGGTGCVIEFCGSAFEQMSMEARMSVCNMSIEAGARAGMIAPDETTFEYIRGRPLAPTGAEWDKAVEYWRSLRSDPDAKYDVDVFIDAADIAPTLTWGTSPQDVVAITGTTPDPSTVSDPIRRQAMERALDYIGLKPNTPMQEVKIDKVFIGSCTNSRIEDLRAAAAIAKGRHVADWVYAMVVPGSGLVKKQAEQEGLDRIFKEAGFDWREAGCSMCLGMNPDQLKPGERCASTSNRNFEGRQGAGGRTHLMSPAMAAAAAVTGYFTDVRKLTPAQQDRPASPTPKKIETELEPPVEDHAKAADQADIVTDAPATGASPPSPAPSDAAGMPKFTTLRGYAAPLDIANVDTDMIIPKQFLKTIKRTGLGTALFYNIRFDGATGEENPDFVLNQEPYRQSRILVCTGPNFGCGSSREHAPWAFNDFGIRSIIAPSFADIFFNNCFKNGMLPITLPQDKVEMLAEHAKQKAELEVDLVNQVVRYPGGEVPFDVEPFRKHCLVNGLDDIGLTMQKADLIEAFEAKRSQTWPWLDGKDYAGKATKFTPVATNTAKKQKLDW
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: GLPK_BACAC
Sequence: MKKYILSLDQGTTSSRAILFNKKGEIVHSAQKEFTQHFPKPGWVEHNAQEIWGSILAVIATCLSEADVKPEQIAGIGITNQRETAVVWDKTTGKPIYNAIVWQSRQTAEICDELKEKGYSEMVREKTGLLIDAYFSGTKVKWILDNVEGAREKAENGDLLFGTIDTWLVWKLSGGKAHVTDYSNASRTLMFNIHDLQWDDELLDMLTVPKSMLPEVRPSSEVYGETIDYHFFGQNVPIAGVAGDQQAALFGQACFGEGMAKNTYGTGCFMLMNTGEKAVASEHGLLTTIAWGIDGKVNYALEGSIFVAGSAIQWLRDGMRMFKDASESEVYASRVESTDGVYVVPAFVGLGTPYWDSEVRGAMFGVTRGTTKEHFIRATLESLAYQTKDVLCAMEADSGIELKTLRVDGGAVKNNFLMKFQSDILDVPVERPVINETTALGAAYLAGLAVGYWKNQDEIKEQWHMDKRFEPTMEAETSEELYAGWKKAIEATKAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RPOC_DESVV
Sequence: MTLDDLFTVRGSAANIANIRNLKAIQITIASPENIREWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKYKRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIWFLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGSTNLTKMQVISEDQYLQVIDHYGEDALTVGMGAEAVRSLLEELNLEELRVQLREESQATKSQTKKKKLTKRLKIVEAFLESNNKPEWMVMEVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPDIIIRNEKRMLQEAVDALFDNGRRGRAITGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKLHQCGLPKKMALELFKPFIYSELEKRGLASTIKSAKKMVEREELVVWDILEEVVREYPIMLNRAPTLHRLGIQSFEPLLVEGKAIQLHPLVCSAYNADFDGDQMAVHVPLSVEAQIECRVLMMSTNNILSPANGSPVIVPSQDIVLGLYYMTVDRSFEKGENMSFCAPWEVVAAYDAGVVALHARINVRMEDGKVVRTTVGRILVWELLPHCVPFSMVNTTLTKKNIARLVSTAYRDAGTKATVILCDRLKDVGYEYATRAGVTIAVKDLTIPSTKKGLIETAQNEVDDIERQYRDGIITRTEKYNKVVDVWTKATQDVSNEMIREISSDIVEDPRTGAKEANSSFNSIYMMSTSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSSFREGLSVLQYFTSTHGARKGLADTALKTANSGYLTRRLVDVVQDVIVSEHDCGTVDGIELTHIKEGGEIKIPLADRALGRVLLYPVYDPETRDLLFPENTLVDENVAKVLVEREVSSVMIRSALTCQSDRGICTLCYGRDLARGHIVNIGETVGIIAAQSIGEPGTQLTMRTFHIGGTASREIERSSFEAQHPGRVILSRVKAVRNRDGQYMVMGKSGQLAIVDDQGREREKYTLPNGSRLLVTEGEEIRKGQILAEWDPFNEPFVSEVDGVIRFSDIVEGKTFQEKMDEATRMTTQTIIEYRTTNFRPSISICDEHGEVKMRGNNIPATYSLPVGAIIMVKNGQDLQAGDIIARKPRETSKTKDIVGGLPRVAELFEVRKPKDMAVVSEIAGIVTYAGETKGKRKLVVTPEIGEAKEYLVPKGKHITVTDGDFVEAGDLLTEGHPELHDILRTRGEKYLARYLTDEIQEVYRFQGVAIDDKHIEVIVRQMLKKVTVLDPGGTTFLVGEQVDKGEFRVENTRAMGEGRTPATAEPLVLGITQASLTTSSFISAASFQETTKVLTEASLRGKMDYLRGLKENVIVGRLIPAGTGYREYVNTDILVPEQRERPDKFLEDLEENPLLVDIY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SWAHD_HUMAN
Sequence: MAQLGGAANRAPTASLAPTSQSLRCAPQPRPSRADTGSLGRYWGKAAAAASREHPFPGTLMHSAAGSGRRRGALRELLGLQRAAPAGWLSEERAEELGGPSGPGSSRLCLEPREHAWILAAAEGRYEVLRELLEAEPELLLRGDPITGYSVLHWLAKHGRHEELILVHDFALRRGLRLDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADATRRDHSGHRACHYLRPDAPWRLRELSGAEEWEMESGSGCTNLNNNSSGTTAWRAASAVGATAVETSRRVAASRTKAKDTAGSRVAQMHSLFRHLFPSFQDR
What are the official names of this protein?
Ankyrin repeat domain-containing protein SOWAHD, Ankyrin repeat domain-containing protein 58, Protein sosondowah homolog D.
What is the protein family that this protein belongs to?
Belongs to the SOWAH family.
Protein: EIPR1_XENLA
Sequence: MEDDAPVIYGLEFQARALTAQTAETDAIRFLVGTQSLRYDNQIHVIDFDDENNIINKNVLLHHAGEIWQIGASPADRNVLATCYNKISDSKVMTCAAVWRIPKELQGGNHESPDDTSSNAQSLELLCHLDSTAHGNMACVTWEPLGDGKKLLSLADNYLLIWDLQESSTKSVLSSSATLEGKGQLRFTSGKWSPHHNCTQVATANDTAIRGWDIRSMRQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNIHEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDEDLSDQEDNPQEEKTKEPLQDSIIGTYEEHEDSVYAVEWSSADPWLFASLSYDGRLVINRVPRALKYNILL
What is the function of this protein?
May act as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network.
What are the official names of this protein?
EARP-interacting protein homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EIPR1 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network.
Protein: RL23_CLAM3
Sequence: MSATQKDPRDIIIAPVVSEKSYGLIDQGKYTFIVDPRSNKTEIKLAIEKIFGVQVASVNTLNKQGKTRRTKFGMGKRKDTKRAIVSLKSGSIDIFTTVG
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RUXE_SCHPO
Sequence: MSGRVQKVMIPPINFIFKLLQQHTPVSIWLFEQTDIRLQGQIRGFDEFMNIVLDDAVQVDAKNNKRELGRILLKGDNITLIQAI
What is the function of this protein?
Involved in pre-mRNA splicing.  Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site.  Involved in cap modification (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein E, snRNP-E, Sm protein E, Sm-E, SmE.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PUR9_BURA4
Sequence: MIKQALISVSDKTGIVDFAKSLSDLGVKLLSTGGTAKLLADAGLPVTEVADYTGFPEMLDGRVKTLHPKVHGGILARRDLPEHMQALEQHDIPTIDLLVVNLYPFVATIAKDDCTLADAIENIDIGGPTMLRSAAKNHRDVTVVVDPADYAVVLDEMKANGNAIGYATNFRLATKVFAHTAQYDGAITNYLTSLTDELQHASRSAYPATLNMAFDKVQDLRYGENPHQSAAFYRDLAAPAGALANYRQLQGKELSYNNIADSDAAWECVKTFDAPACVIIKHANPCGVAVGNDSADAYAKAFQTDPTSAFGGIIAFNREVDEAAAQAVAKQFVEVLIAPSFSDAAKQVFAAKQNVRLLEIALGDGHNAFDLKRVGGGLLVQSLDSKNVQPSELRVVTKRQPSAKEMDDLLFAWRVAKYVKSNAIVFCGNGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVVVAAGATCVIQPGGSMRDDEVIAAADEHGIAMILTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SYFA_DESHY
Sequence: MKQEVHRIQEETLAELQQVSTLEALQELKVKVLGKKGSLTAQLRKMGGLSPEERPIFGQVVNETRDILEAAWIRREEELSQTAMLKQLEEEKLDISLPGVSLPQGHQHPLTKVIEEIEEIFLGMGFQIAEGPEIESDYYNFEALNLPKDHPAREMQDSFYITEEILLRTQTSPVQIRTMEKQRPQLPVKIICPGKVYRNDDDATHSPMFHQVEGLMVDRRIRMSDLKGILLSFSRMMFGESREIRLRPSFFPFTEPSAEVDVSCMLCGGAGCRICKGTGWIEILGSGMVHPRVLEMGGYDSKELTGFAFGMGVERIAMLKYGIEDMRLLFDNDLRFLQQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB1_STAAW
Sequence: MHRQFLSSRCQNLFFKFKLLLFEVNQMQYVYIFIGGALGALLRYLISFLNTDGGFPIGTLIANLTGAFVMGLLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQLELIHMFDHQQFITLLLYAVTSYVFGILLCYVGIKLGGGLS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRSA2_LISMF
Sequence: MKKKLILGLVMMMALFSLAACGGGGDVVKTDSGDVTQDELYDAMKDKYGSEFVQQLTFEKILGDKYKVSDEDVDKKFNEYKSQYGDQFSAVLAQSGLTEKSFKSQLKYNLLVQKATEANTDTSDKTLKKYYETWQPDITVSHILVADENKAKEVEQKLKDGAKFADLAKEYSTDTATKDNGGQLAPFGPGKMDPAFEKAAYALKNKGDISAPVKTQYGYHIIQMDKPATKTTFEKDKKAVKASYLESQLTTENMQKTLKKEYKDANVKVEDKDLKDAFKDFDGSSSSDSDSSK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 2.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DHAS_HELPJ
Sequence: MKTYNVAIVGASGAVGQELIKGLENSFFPIKKFVPLASARSAGKKIRAFNKDYEILETTHEVFEKEEIDIAFFSAGGSVSEEFAISASKTALVIDNTSFFRLNKDVPLVVPEINAQEIFNAPLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGIESLKNELKTALEHLEKDPAIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMVHETHKIMGVDFPISATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVVVCDDPSHNLYPTPLKASHTDSVFIGRLRKDLFDKKTLHGFCVADQLRVGAATNALKIALHYIKNA
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: RNH3_STRPC
Sequence: MNTLVLKIDAILSKHLKKQLASYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGLS_PSEPK
Sequence: MPANDFVSPDSIRAQFSAAMSLMYKQEVPLYGTLLELVSEINQQVMAQQPEVAEALRWTGEIERLDQERHGAIRVGTAEELATIARLFAVMGMQPVGYYDLSSAGVPVHSTAFRAVHEQSLHVSPFRVFTSLLRLELIDNPQLRELAQSILAKRQIFTSRALELIAQCEREGGLDAADAETFVQEALHTFRWHQDATVTAEQYQQLHDQHRLIADVVAFKGPHINHLTPRTLDIDAIQLGMPAKGIPPKAVVEGPPTRRHPILLRQTSFKALQETVAFRDQQGREGSHTARFGEIEQRGAALTPKGRQLYDKLLDATRVALGGAPAEANAERYMALLQANFAEFPDDLAQMREQGLAYFRYFATEKGLAARDQEGRPTTLQGLIDAGHVHFEALVYEDFLPVSAAGIFQSNLGDDAQAEYGSNANREAFEAALGLQVQDELALYAQSERRSLQACAQALNLGSM
What is the function of this protein?
Catalyzes the decarboxylation and hydroxylation of 2-oxoadipate (2OA) to form D-2-hydroxyglutarate (D-2-HGA) (PubMed:31064836, PubMed:32523014).  Is specific for 2-oxoadipate (PubMed:32523014).  Is involved in a D-lysine catabolic pathway (PubMed:31064836).
What are the official names of this protein?
2-oxoadipate dioxygenase/decarboxylase, 2-hydroxyglutarate synthase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.
Protein: BIOF_BURP1
Sequence: MNPLATLEQGLADIDAQGLRRCRRVADTACGAHMTVDGRAIIGFASNDYLGLAAHPRLVEAFAEGARRYGSGSGGSHLLGGHSRAHATLEDQLAAFSGGFSDAPRALYFSTGYMANLAALTALAGRGATIFSDALNHASLIDGARLSRANVQIYPHGDADALDARLRACDAPTKLIVSDTVFSMDGDVAPLARLVALAETHGAWLVVDDAHGFGVLGPQGRGALAAHGLRSPNLVYVGTLGKAAGVAGAFVVAHETVIEWLVQRARSYIFTTAAPPSVACAVSASLAVIASDEGDARRAHLGALIKRTRAILRATHWQPVDSHTAVQPLVIGSNEATLAAMAALDAQGLWVPAIRPPTVPAGTSRLRISLSAAHSFDDLARLEAALVTPIGAAA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: ANR49_BOVIN
Sequence: MEKEKVNDEKPDPENSLDFSEHFNQLELLETHGHLIPTGTQSLWIGNSDDDEEQDEKTEEWYQLQEKKMEKDPSKLLLWAAEKNRLTTVQRLLSERATHVNTRDEDKYTPLHRAAYNGHLDVVRELIAHGADVHAVTVDGWTPLHSACKWNNARVASFLLQHDADVNAQTKGLLTPLHLAAGNRDSKDTLELLLMNRYIKPGLKNSLEETAFDIARRTGIYHYLFEIVEGCTNCSPQS
What is the function of this protein?
May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 49.
What are the subcellular locations of this protein?
Nucleus.