PharMolix/UniProtQA huggingface dataset:
Protein: CBIA_HALH5
Sequence: MQPRLVIAGTHSGVGKTTVTLGLMAAFVEKGNIVQGFKCGPDYIDPSYHRAVTKRASRNLDSWMVSEDVVNDIFIEGCNGADLSIIEGVMGFYDGKASTSDKGSTADISLLLQAPVLLVVDISGMARSAAAVVKGFQQLNEKVKIAGVILNGAGSERHAEMCSEAIKEACGIPALGYLKKGDVPSIPERHLGLVPALERGEHDSLFSQLAAVVSRQFDLERIERLALEASALSRRTNLFQQTKRPSVVKIAVAYDAAFHFYYEENFTLLRQAGAELVYFSPLRGEDLPSHCDGLYLGGGFPEEFADELSQWIKDHPQLKKRVQSGLPTLAECGGYMFLGEQLTTTKGKTVEMAGVIPMVVQMENKLVSLGYRDVTPLDDSFLLSKGQQIRGHEFHYSKAVYTETERPAYFVKGLFGEGKEGYMSDHLLAGYTHLHFASEPAVATQWVKACEVYKNRRLHRGQVSQ
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: EX7S_SOLM1
Sequence: MSVKEESFEKALARLERIAVALEAGDVPLEKGVALYKEGMGLVASCRKRLEAARLEISLAGEDGAVVPFDVADDEAARDGGPAGEES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULK3_HUMAN
Sequence: MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMPSGESLGRATALVVQAVKKDQEGDSAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQALLRQGTSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKMRESRWEADTLDKEGLSESVRSSCTLQ
What is the function of this protein?
Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy.  Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3).  Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation.  Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.  Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
What are the official names of this protein?
Serine/threonine-protein kinase ULK3, Unc-51-like kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
Protein: GLGB_CHLTA
Sequence: MDPFFLNTQHVELLVSGKQSSPQDLLGIVSESLNQDRIVLFRPGAETVFVELRGKIQQAESHHSGIFSLPVMKGISPQDYRVYHQNGLLAHDPYAFPLLWGEIDSFLFHEGTHQRIYERMGAIPCEIDGVPGVRFIVWAPHAQRVSVIGDFNGWHGLVNPLHKVSDQGVWELFVPGLTAGACYKWEMVTESGQVLIKSDPYGKFFGPPPRSVSVVIDDSYEWTDSEWLEERIKKTEGPMNIYEVHVGSWRWQEGQPLNYRELADQLALYCKQMHYTHVELLPVTEHPLNESWGYQTTGYYAPTSRYGSFEDLQYFIDTMHQHGIGVILDWVPGHFPIDSFAMSGFDGTPLYEYTRNPSPLHPHWHTYTFDYAKPEVCNFLLGSVLFWIDKMHVDGIRVDAVSSMLYLDYGRYAGEWVPNRYGGRENLDAIRFLQQFNTVIHEKYPGVLTFAEESTTFPKITVSVEEGGLGFDYKWNMGWMHDTLHYFEKDFPYRPYHQSDLTFPQWYAFSERFLLPFSHDEVVHGKRSLIGKMPGDAWRQFAQLRLLLGYQICQPGKKLLFMGGEFGQGREWSPGRELDWELLDISYHQGVHLCSQELNALYVQSPQLWQADHLPSSFRWVDFSDVRNGVVAYLRFADADAKKALLCVHHFGVGYFPHYLLPILPLESCDLLMNTDDTRFGGSGKGFREPEILTPEIARQEREAAGLIEADDESGPDCWGLDIELPPSATLIFSVTLQ
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: MATRX_MEASU
Sequence: MTEIYDFDKSAWDIKGSIAPIQPTTYSDGRLVPQVRVIDPGLGDRKDECFMYMFLLGVVEDSDSLGPPIGRAFGSLPLGVGRSTAKPEELLKEATELDIVVRRTAGLNEKLVFYNNTPLTLLTPWRKVLTTGSVFNANQVCNAVNLIPLDTPQRFRVVYMSITRLSDNGYYTVPRRMLEFRSVNAVAFNLLVTLRIDKAIGPGKIIDNTEQLPEATFMVHIGNFRRKKSEVYSADYCKMKIEKMGLVFALGGIGGTSLHIRSTGKMSKTLHAQLGFKKTLCYPLMGINEDLNRLLWRSRCKIVRIQAVLQPSVPQEFRIYDDVIINDDQGLFKVL
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: A1LC_LOXAR
Sequence: WIMGHMVNAIYQIDEFVDLGANSIEVDVSFDDNAKPEYTYHGIPCDCRRWCTKWEYFNDFLKALRKATTPGDSKYHEKLVLVVFDLKTNSLYNYQAYDAGKKLAENLLQHYWNNGNNGGRAYIVLSIPNLAHYQLITGFKETLKNKGHPELMDKVGHDFSGNDNIDQVEKAYKKAGVTGHVWQSDGITNCIASFIRGLDRAKKAVKNRDSSNGYINKVYYWTVDKYATTREALDIGVDGIMTNYPDVIANVLNESAYKEKFRLATYDDNPWEAFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LarSicTox-alphaIB2c, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YOPQ_BACSU
Sequence: MTVIFDQSANEKLLSEMKDAISKNKHIRSFINDIQLEMAKNKITPGTTQKLIYDIENPEVEISKEYMYFLAKSLYSVLESERFNPRNYFTETDMREIETLWEGSVEEDIKFPYTFKQVVKYSDDNYFFPITAKELFMLFENKLLHYNPNAQRTNKTKKLEGSDIEIPVPQLNKQSVEEIKELFLDGKLIKSVFTFNARVGSASCGEELKYDDDTMSLTVTEDTILDVLDGYHRLIGITMAIRQHPELDHLFEETFKVDIYNYTQKRAREHFGQQNTINPVKKSKVAEMSQNVYSNKIVKFIQDNSIIGDYIKTNGDWINQNQNLLITFSDFKKAIERSYSKKDFSTQADILKTARYLTSFFDALATQYVDEFLGDIAKERKRSFVNNYLFFNGYVGLAKKLQLDGVSLDELESKITDVLGSIDFSKKNKLWDELGVVDKNGNAKSPQKIWNFFNNLKIDE
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YopQ.
Protein: FUS_HRSV1
Sequence: MELLIHRSSAIFLTLAVNALYLTSSQNITEEFYQSTCSAVSRGYFSALRTGWYTSVITIELSNIKETKCNGTDTKVKLIKQELDKYKNAVTELQLLMQNTPAANNRARREAPQYMNYTINTTKNLNVSISKKRKRRFLGFLLGVGSAIASGIAVSKVLHLEGEVNKIKNALLSTNKAVVSLSNGVSVLTSKVLDLKNYINNRLLPIVNQQSCRISNIETVIEFQQMNSRLLEITREFSVNAGVTTPLSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSIIKEEVLAYVVQLPIYGVIDTPCWKLHTSPLCTTNIKEGSNICLTRTDRGWYCDNAGSVSFFPQADTCKVQSNRVFCDTMNSLTLPSEVSLCNTDIFNSKYDCKIMTSKTDISSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKLEGKNLYVKGEPIINYYDPLVFPSDEFDASISQVNEKINQSLAFIRRSDELLHNVNTGKSTTNIMITTIIIVIIVVLLSLIAIGLLLYCKAKNTPVTLSKDQLSGINNIAFSK
What is the function of this protein?
Major determinant of the species specificity of RSV infection.  The trimer of F1-F2 (F protein) also facilitates the attachment to host cell by binding to host heparan sulfate.  F protein is involved in the entry into the host cell through the interaction with host IGFR1.  This interaction activates PRKCZ/PKCzeta that recruits host NCL/nucleolin to the apical cell surface where it can bind fusion glycoprotein F1.  Later in infection, F protein expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis.  F protein seems to trigger p53-dependent apoptosis.
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
[Fusion glycoprotein F0]: Host Golgi apparatus membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Fusion glycoprotein F1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein. Note=Localized at the host apical membrane. SUBCELLULAR LOCATION: [Fusion glycoprotein F2]: Virion membrane. Host cell membrane. Note=Localized at the host apical membrane.
Protein: RS7_PROM3
Sequence: MSRRNAAEKRPVLPDPQFNNRLATMMISRLMKHGKKSTAQRILAQAFGLINERTGGDPIELFETAVKNATPLVEVRARRVGGATYQVPMEVRQERGTAMALRWLVNFSRARNGRSMSQKLAAELMDAANEAGSAVRKREETHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: 3HAO_PSEFL
Sequence: MMFTFGKPLNFQRWLDDHSDLLRPPVGNQQVWQDSDFIVTVVGGPNFRTDFHDDPMEEFFYQFKGNAYLNIMDRGQMDRVELKEGDIFLLPPHLRHSPQRPEAGSRCLVIERQRPKGMLDGFEWYCLSCNGLVYRVDVQLNSIVTDLPPLFDIFYGNVGLRKCPQCGQVHPGKAAIEAVARGDQP
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
Protein: PYRC_AERPE
Sequence: MAGWTVCVDFLYTGDKMLEDACAVISGERVERVHTGGFRGQPDLDLRGRSSLALPGVIDMHVHLRGLKLSYKEDEVSGTAAAASGCVTLVADMPNTQPPLRTPEALREKLASLEAGAKVDYTVYAGVPRSYGEAVEMASMGIAGFKIYPEDLVNLDSIKNVLEAAEEAGILVVLHPESHDMFAGPDYGWLRRVARPCHAEAASVELLHDAARECGCKPRVHITHASCPATVVESKKRGFTVDVTPHHLFLSEEEVAGPTHSWGKVNPPLRGVGERSLLTQLTIEGLVDAIASDHAPHSTWEKWMHPAIAPPGFPWLEWWPGFTAARLMRAVGLERFYSMVSQTPSTILGVGDRCLWDGCPATISVLQLERTRVYHKGYTKALYTPVLGMESFDCAATVIRGKIAYTAWEGVRGGATGVLATRVVH
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: CSM2_YEAST
Sequence: MEYEDLELITIWPSPTKNKLCQFIKQNLSKEHVVTQLFFIDATSSFPLSQFQKLVPPTLPENVRIYENIRINTCLDLEELSAITVKLLQILSMNKINAQRGTEDAVTEPLKIILYINGLEVMFRNSQFKSSPQRSHELLRDTLLKLRVMGNDENENASIRTLLEFPKEQLLDYYLKKNNNTRTSSVRSKRRRIKNGDSLAEYIWKYYADSLFE
What is the function of this protein?
Involved in chromosome segregation during meiosis.  Promotes efficient recombinational repair and functions in the protection of the genome from spontaneous and induced DNA damage like mutations and gross chromosomal rearrangements (GCRs).
What are the official names of this protein?
Chromosome segregation in meiosis protein 2.
What is the protein family that this protein belongs to?
Belongs to the CSM2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: H3_DROME
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GLMU_KINRD
Sequence: MTTQPAVPAAVIVLAAGEGTRMRSATPKVLHPLGGRPLVGHALRAARGTAPEHLVVVLRHQADRVREALAGDFPSVLVALQDDVPGTGRAVQCALEALPADLSGTVLVTYGDVPLLSSATLQRLAGAHAAGGNAVTVLTALLADPTGYGRVLRDGTGVTGIVEQKDATAEQLAVREVNSGVYAFEAAALRESLGRVGRDNAAGEVYLTDVLSLVRAAGGRVEALALEDEWEIRGVNDRAQLADLAAEANRRTLRRWMLAGVTIADPATTWIDADVELAPDVTIRPGVQLHGTTRVATGAVVGPDSTLTDVEVGAGALVERTHGSSAVVGEGAQVGPFAFLRPGTRLGAEGKIGTFVETKNATIGRGSKVPHLSYVGDATIGEHSNIGAASVFVNYDGVNKARTTVGDHVRMGSDNMYVAPVTVGDGAYSGAGTVIRKDVPAGALAINVAPQRNLEGWTLAKRPGTPAAEAAQRANDESTGTTASTDREIQP
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMC4_BOVIN
Sequence: MPQKDPCQKQACEIQKCLQANNYMESKCQAVIEELRKCCARYPKGRSLICSGFEKEEEEKQTLKCTPQ
What are the official names of this protein?
Cx9C motif-containing protein 4, Mature T-cell proliferation 1 neighbor protein.
What is the protein family that this protein belongs to?
Belongs to the CMC4 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GIP4_CANGA
Sequence: MLARSAASLSTTAATTQSNMSVTSQFMDANDCKFIVYKASQIRLTEMKRLLGVLVPNLKKRSSQNKNIVPLVTYMLPLLAGPVLNVNAALKEKYNQIVQGQEPTKDNKDYDVTPRDWLTYVMDSNTQNQPLEGCELVEFKKELYDKDKQWLTVTRLLKLIDEVISTYNNKFKSANLLKKTYSKSIEDLIKPSELSLCLDLAVLITDYERDTSEASFRKLQWQVIEKFLATLHSKVEPTLKTYYKSLLAYQSGKLMLYKLPFPEWTIHRMFAFTVRMISLMKLFGCELRVLYYPNRKYLNDLKTKLVCENVYKYDLLITQIEKLCADPLYQIKESKEMMQFFQKYPYSLPKSLPQKTHEFFIKKVISTCINHWNNNTKLVEDWVEMWKFCDKNNSAKEKIESSNEEQLIKMYDERYTVDKLVYLEHEEERAKLSNKKSIGIVVKSSSSSSPNKLLRKLSPISGMAKPKVRSTKSPASSSSSNSNSNSALSSGMATPKERSRRSSVDRGLPKGGRLPGLTKTNTNERLVAPLIHISETSSVSNSGSSSINASPLGSRRGSIKDESAARKMVINRTVERTRSKIGNRPRSASLQSNESAALNSVGIVGSPLSNNRLPKPVSNQSQLRSNSLESNSALNRKMVQDTFKHLMANNPKPSNLSHSPTSSPMRPSSPIPSRSNSNKVSSTNNGAILSPEPKGKSKANNSNDKIKTNGVTSINIDNSDNEIVLKPLPHESKDTTTGPVRPVDESVNNLSEGTPAGSESTPESMKSAVGIEGLDKENLNVESGNMESGEPSKKVRFVGVPPMTEAENPKPTRKGWYKKPAVLHYPPVPQQVTMFRDRLRQEGMVFRTSLRDTVAATSNEVGKKGGMMLSLAIDNPPVKEISSHSRFASKLREKLTR
What is the function of this protein?
GLC7 phosphatase-regulatory protein involved in GLC7 subcellular redistribution and chromosome segregation.
What are the official names of this protein?
GLC7-interacting protein 4.
What is the protein family that this protein belongs to?
Belongs to the GIP4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTFA_STRPA
Sequence: MTIYNINLGIGWASSGVEYAQAYRAQILRSLGMPAKFIFTNMFQSENLEHFTKNIGFEDNEIIWLYGYFTDVKISGTTYKKDDLEATFSQCPTKKEASSDRKLIRYYFENQELYINASLYGENQEYVQRVEYVVKGKLIRKDYYSYTKVFSEFYSPGENGVQLCNRSFYNEDGSIAYEEILSNEKSTFVFSNKICYGLEELLEFMLEDLSLTKSDLILLDRATGIGQVVFENIGAAKLAVVIHAEHFNEKNTDEHNILWNNYYEYQFTNADKVNAFITSTERQKILLEEQFTQYTSLHPKIVAIPVGSLDQLKFPEQSRKSFSMMTGSRLAIEKHIDWLIEGVALAQKRLPELTFDIYGEGGERRKLTELLTKLHAGEFIELKGHKQLDEIYQNYELYLTASTSEGFGLTLMEAVGSGLPIIGFDVPYGNQTFVCSGENGLLIERPKGDDRSRIVQAFADSIYEYFTKFKMADAQQYSYNIAENYKHEKLVERWKDFIEEMLND
What is the function of this protein?
Required for polymorphic O-glycosylation of serine-rich repeat protein Fap1.  Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in Fap1.  Part of the accessory SecA2/SecY2 system specifically required to export Fap1, a serine-rich fimbrial adhesin encoded upstream in the same operon.  The GtfA-GtfB (Gtf1-Gtf2 in this bacteria) complex adds GlcNAc from UDP-GlcNAc to Fap1, attaching the first sugar residue.  Cannot use not UDP-Glc as substrate.  This subunit has very low glycosyltransferase activity; the GtfB stabilizing protein enhances membrane association, protease resistance and glycosyltransferase activity.
What are the official names of this protein?
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase GtfA subunit, Glycosyltransferase Gtf1, Glycosyltransferase GtfA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Cell membrane association requires GtfB (Gtf2), protein is more active and protected from trypsin (PubMed:21862581).
Protein: KDGD_PSEPF
Sequence: MNPQELKSILSAGLLSFPVTDFNAQGDFNRAGYIKRLEWLAPYGASALFAAGGTGEFFSLAASEYSEIIKTAVDTCASSVPILAGVGGSTRQAIEYAQEAERLGAKGLLLLPHYLTEASQDGVAAHVEAVCKSVNIGVVVYNRNVCRLTAPLLERLAERCPNLIGYKDGLGDIELMVSIRRRLGDRFSYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMDFYHAIAREDHATVGKIIDDFFLPYLDIRNRKAGYAVSIVKAGAKIAGYDAGPVRAPLTDLTGEEYEMLAALIDKQGAQ
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: Y1550_ENT38
Sequence: MYPVDLHMHTVASTHAYSTLHDYIAQARLKGIKLFAITDHGPDMADAPHYWHFVNMRIWPRLVDGVGILRGIEANIKNTDGEIDCTGPMLTSLDMIIAGFHEPVFPPQDKDTHTQAMIATIASGNVHIISHPGNPKFPIDIQAVAQAAAKHRVALEINNSSFTHSRMGSEANCRAVAAAVRDAGGMVALGSDSHTAFTLGEFTECRKVLDEVGFPEERILNVTPRRMLDFLESLGMPHIPEFADL
What are the official names of this protein?
Probable phosphatase Ent638_1550.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: GAM1_ADEG1
Sequence: MARNPFRMFPGDLPYYMGTISFTSVVPVDPSQRNPTTSLREMVTTGLIFNPNLTGEQLREYSFSPLVSMGRKAIFADYEGPQRIIHVTIRGRSAEPKTPSEALIMMEKAVRGAFAVPDWVAREYSDPLPHGITHVGDLGFPIGSVHALKMALDTLKIHVPRGVGVPGYEGLCGTTTIKAPRQYRLLTTGVFTKKDLKRTLPEPFFSRFFNQTPEVCAIKTGKNPFSTEIWCMTLGGDSPAPERNEPRNPHSLQDWARLGVMETCLRMSRRGLGSRHHPYHSL
What is the function of this protein?
Early protein essential for viral replication.  Strong and global transcriptional activator of both viral and cellular genes.  Activates transcription by blocking host retinoblastoma protein (RB) and inhibiting the SUMO pathway.  Inhibition of host RB leads to the activation of E2F1-dependent transcription and, in particular, of E2F1-regulated S-phase genes.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  Blocks the SUMO pathway by targeting the E1 enzyme (SAE1/UBA2 heterodimer) to the ubiquitin-proteasome machinery.  Mediates SAE1 degradation possibly through the formation of complexes with either CUL2-elongin BC complex-RBX1 or CUL5-elongin BC complex-RBX1.  The degradation of UBA2 is probably a consequent effect of SAE1 disappearance.  Inhibits HDAC1 sumoylation, thereby interfering with histone deacetylation mediated by HDAC1, leading to activation of transcription.  Mediates induction of heat-shock response.  Seems to have an antiapoptotic function.
What are the official names of this protein?
Protein GAM-1, Gallus-anti morte protein, Gam1.
What are the subcellular locations of this protein?
Host nucleus.
Protein: YCIB_SHESW
Sequence: MKQLLDFLPLVIFFAVYKFFDIYIASGALIAATALQLIVTYALYKKLEKMHLITFAMVTVFGTLTLVFHDDAFIKWKVTIIYALFALALGISQLLNKSILKSMLGKEMQVADKIWAHITWYWVIFFATCGLVNIYVAFSLPLETWVNFKVFGLTALTLVNTVITVFYLYKHLPEDQRKELK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KRBBA_MOUSE
Sequence: MDSTTLVYADLNLARIQEPKHDSPPSLSPDTCRCPRWHRLALKFGCAGLILLVLVVIGLCVLVLSVQKSSVQKICADVQENRTHTTDCSVNLECPQDWLSHRDKCFRVFQVSNTWEEGQADCGRKGATLLLIQDQEELRFLLDSIKEKYNSFWIGLRFTLPDMNWKWINGTTFNSDVLKITGDTENGSCASISGDKVTSESCSTDNRWICQKELNHETPSNDS
What is the function of this protein?
Receptor for CLEC2D/OCIL.  Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells.  May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells.
What are the official names of this protein?
Killer cell lectin-like receptor subfamily B member 1B allele A, CD161 antigen-like family member B, Lymphocyte antigen 55b, Ly-55b, NKR-P1 34, Natural killer cell surface protein NKR-P1B allele SJL/BALB, NKR-P1B.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: S27A6_HUMAN
Sequence: MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL
What is the function of this protein?
Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane (PubMed:12556534).  Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (By similarity).  Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation such as the heart (PubMed:12556534).
What are the official names of this protein?
Long-chain fatty acid transport protein 6, FATP-6, Fatty acid transport protein 6, Arachidonate--CoA ligase, Fatty-acid-coenzyme A ligase, very long-chain 2, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 6, Very long-chain acyl-CoA synthetase homolog 1, VLCSH1, hVLCS-H1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36.