PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_STUS1
Sequence: MIATTGKVNLLGLTQPQLESFFESIGEKRFRAGQVMKWIHHFGVDDFDAMSNLGKALREKLKACAEIRGPEIVSEDISSDGTRKWVVRVASGSCVETVYIPQGGRGTLCVSSQAGCALDCSFCSTGKQGFNSNLTAAEVIGQVWIANKSFGTVPAKIDRAITNVVMMGMGEPLLNFDNVVAAMQIMMDDLGYGISKRKVTLSTSGVVPMIDELAKVIDVSLALSLHAPNEALRDQLVPINKKYPLDVLLAACKRYVSRLGEKRVLTIEYTLLKGVNDQPEHAEQMIALLADIPCKINLIPFNPFPHSGYERPSNNAIRRFQDILHKGGHNVTVRTTRGEDIDAACGQLVGQVLDRTRRSERYIAVRELQSEPGAAQTASNRS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
Protein: CBID_BURMA
Sequence: MRDETPEQPAPLRFGYTTGSCASATSLAAARLLLTGVASDTVDIVLPKGQHVAMRLAFCRATDDGGAEAGTIKDAGDDPDVTHGALVFARVRLVHEPGVRFRAGPGVGTVTRAGLPIAVGEPAINPVPRRMMTEHLAALAAEHGYAGGFDVAIGVENGEALARKTMNPRLGIVGGLSILGTTGIVRPFSCSAYIASIHQGIDVARANGVTHIAACTGNASEDAVRARYGLPDIALIEMGDFAGAVLKYLRRASVARLTLCGGFGKLSKLAAGHLDLHSRHSSIDLPLLAEWAGEAGASAVLQHEIRAANTSQQALALALAHHVPLGDVVCAHARRVARDIVPGEVDVETLAIDREGRIVGVVP
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: RL15_PELPD
Sequence: MDLNTLKPALGSVKQGKRIGRGPGSGHGKTATKGHKGQKARSGGSIKAGFEGGQMPLQRRLPKRGFTPLSRVEYAIVNLKQLDAFEANSSVDTESLVAMGLVKSTACAVKILGNGDLAKSLRVSASKFSQSAKDKILAAGGTVEETV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: NUSB_GLOVI
Sequence: MQARRIARELALMSIGQMPADRSRLQAKNLEELVLASVRTLREEANESLQRACTELRQGHNRLEASELTAPTVEAARREVAAAIALAEQAINRVGASLELPEFVRLADELQVRAYAFELLGAFVREGDNLDKLLDTCMEGWQVERLTRIDRDILRLALVEMVELKSVPFRVAIDEAVELAKKYSTDTAVRFINGVLRRVVQHLQLEQRPRR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: QUEA_STAAS
Sequence: MNIEEFDYDLPESLIAQTPLKDRDHSRLLVMDRETGEMKHLHFKDIIEYFRPGDTLVLNDTRVMPARLFGLKEETGAKVEMLMLTQIEGNDWEVLLKPAKRIKVGNKLNFGNGKIIAECIKEMDQGGRIMRLHYEGILQERLDELGEMPLPPYIKERLDDPDRYQTVYAKESGSAAAPTAGLHFTDELLTEIKNKGVNIAFVTLHVGLGTFRPVSVDDVNDHEMHSEYYQMTQETADLLNDTKSKGHRIISVGTTSTRTLETIRRDHDKFVETSGWTNIFIYPGFDFKAIDGQITNFHLPKSTLVMLVSAFSTRENVLNAYKTAVNLEYRFFSFGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTP_SULSN
Sequence: MSFFTKTAQLVSGAAVAATLFTATAQAETVLRGASMFDEEHAFTKTLRKFEELVDEKYDGDVTFDLRLNGELGVESDYVTFLNQGVAIDYTILAPSNMAKFAPSIPLMDMPFLFRDLDHWNAVLSSDVLAPLEDELLEKADIKIVGYTGGGTRNLLSKQPVVTFDDLKGHKMRVMGAPIQAQIFQALTAAPSAIAYNEVYNAIQTGVIAGFENEAASIQNLKFYEVAPNLTLTRHSITVRPIVMSGKTFNSLPADLQAVVLEAGEEAGAYGRELESREDGVKLQEMVDAGQLTVSEFENRDKMLEMVKPVQDAYAAEIGASDLLEAVRAK
What is the function of this protein?
Solute-binding protein that binds D-mannuronate and D-taluronate (in vitro) (PubMed:25540822).  Probably part of a tripartite ATP-independent periplasmic (TRAP) transport system that mediates solute transport into the cytoplasm.
What are the official names of this protein?
Solute-binding protein NAS141_03721.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: APC4_PONAB
Sequence: MLRFPTCFPSFRVVGEKQLPQEIIFLVWSPKRDLIALANTAGEVLLHRLASFHRVWSFPPNENTGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPGSLHSFSVEAPVSCMHWMEVTVESSVLTSFYNAEDESNLLLPKLPTLPKNYSSTSKIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCLALCLSSDLKSLSVVTEVSTNGASEVSYFQLETNLLYSFLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMHLLLWGKASAELQTLLMNQLTVKGLKKLGQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGLASWKQKYEPLGLDAAGIEEAITAVGSFILKANELLQVIDSSMKNFKAFFRWLYVAMLRMTEDHVLPELNKMTQKDITFVAEFLTEHFNEAPDLYNRKGKYFNVERVGQYLKDEDDDLVSPPNTEGNQWYDFLQNSSHLKESPLLFPYYPRKSLHFVKRRMENIIDQCLQKPADVIGKSMNQAICIPLYRDTRSEDSIRRLFKFPFLWNNKTSNLHYLLFTILEDSLYKMCILRRHTDISQSVSNGLIAIKFGSFTYATTEKVRRSIYSCLDAQFYDDETVTVVLKDTVGREGRDRLLVQLPLSLVYNSEDSAEYQFTGTYSTRLDEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHVRVFEMDIDDEWELDESSDEEEEASNKPVKIKEEVLSESEAENQQAGAAALAPEIVIKVEKLDPELDSQSSLPLLCV
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 4, APC4, Cyclosome subunit 4.
What is the protein family that this protein belongs to?
Belongs to the APC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SP51_DICDI
Sequence: MRINNLLVCLVLVFSTLSISNANPEHDKWWKPPPRNCDSLSEDQCKAPNSGCKYLPFVSCCGTKKFFCVEDNGNGCGNAPLSCMKDSKTDAIYEIWSSCRPNSPFLYDYQVRNETCDQKLCEASGGVCEWVDPVPCMGTSCCPRYPVCKGGGGGGGPVSPCKNVICPEDYCCQDIHGGAYCVEKPRPPPPKPHHLCKAIKCGRGKECIVKDGKACCVPKPKPPPPPPVLCDAVQCPKGFNCVEFGGTANCVECEEKECEHHHCPPGYDCVVDSHHRPHCQRPNPGSLCRNVTCPYGYVCKAINNLPTCIRNPLPPNYPCRDLHCPSGYSCEIINDLPSCVRETHPGHCKTCHDVNCGSLDCAMVPNKCPRGSRDCCIQIPSCRLPSNSNDDYDNDPNGYDDNENEGDGLSIPCGPIITCKLNEICLLEQSRCAPLCEFVKCSPGTKCVADTTGIPVCLPNGITPY
What is the function of this protein?
May contribute to the structure of the coat at the interface between the middle, cellulosic layer and the outer, electron-dense, proteinaceous layer.
What are the official names of this protein?
Probable spore coat protein DDB_G0283555.
Protein: IF2_SHIDS
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPSTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_SHIB3
Sequence: MSIKEQTLMTPYLQFDRNQWAAQRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRT83_HUMAN
Sequence: MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQGRH
What are the official names of this protein?
Keratin, type II cuticular Hb3, Hair keratin K2.10, Keratin-83, K83, Type II hair keratin Hb3, Type-II keratin Kb23.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RS20_MARMM
Sequence: MANTNSAKKMVRKIARRTAVNKARRSRVRTFVKKVEMAITSGDQAAAKTALVEAESELMRAVGKGVYHKNTGSRKVSRLSARVKSMSA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS2_ECO8A
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CAPSD_BGYMV
Sequence: MPKRDAPWLMAGTSKVSRSGNYSPSGGMGSKSNKANAWVNRPMYRKPRIYRMYKSPDVPKGCEGPCKVQSYEQRHDISHVGKVMCISDITRGNGITHRVGKRFCVKSVYILGKIWMDENIMLKNHTNSVIFWLVRDRRPYGTPMDFGQVFNMFDNEPSTATVKNDFRDRYQVMHRFNAKVSGGQYASNDQALVRRFWKVNNHVVYNHQEAGKYENHTENALLLYMACTHASNPVYATLKIRIYVYDSITN
What is the function of this protein?
Encapsidates the viral DNA into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  The CP of bipartite geminiviruses is not required for cell-to-cell or systemic movement.
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).
Protein: RL35_WHEAT
Sequence: MSSGKVKAGELWNKSKDDLTKQLAELKTELGQLRIQKVASSGSKLNRIHDIRKSIARVLTVINAKQRAQLRLFYKNKKYAPLDLRAKQTRAIRRRLSPDEKSRVLEKTKKRTVHFPQRKFAIKA
What are the official names of this protein?
60S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PSF3_CRYNJ
Sequence: MEDDYFSITSILADNHKMSCTFALDAEGLGYLEGSTENDIHEGTKVELPFWLAQTLSVNQFTTFTLPLPYSSRVQSALVASPVSVKLSNLVGGNGWWYRWGKKLADMLEDEQATNIRNMLLRAFTGRLPTLQDLAAHHASADHTMPELSTSKAEMFRDGMEGDERELFSIGQDSGRLFKAWYDRKKGSR
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
DNA replication complex GINS protein PSF3.
What is the protein family that this protein belongs to?
Belongs to the GINS3/PSF3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYAB_STIAU
Sequence: MLQGHHRVMVVDDSPLACDFVKEGLEALGLGYEVMCFQDPYEALEQVGKVQPAIVLSDLDMPGIDGLELCWRLKESPSRQVPVIILTANDSEAERVKGLRAGADDYVNKSASMAELSARIESVMRRTSETERMRKLFARYTSDAVVEEILKSPDTVVLTGEKPEVTVLFADIRNFTGLAESLPPEQVVGVLNQVLGRLSDAVLTCGGTLDKFLGDGLMAVWGAPVHRTDDALRALQAAKMMMTAMVELRQAAQAEWAANERLGRPLVLELGIGINSGLAVAGNIGGSMRTEYTCIGDAVNVAARLCALAGPGEILAGERTRELVSHREMPFEDLPPVRLKGKQQPVPLYRVL
What are the official names of this protein?
Adenylate cyclase 2, ATP pyrophosphate-lyase 2, Adenylyl cyclase 2, AC2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the adenylyl cyclase class-3 family.
Protein: PYRH_PSEPK
Sequence: MAQQVSGRQPRYKRILLKLSGEALMGSEDFGIDPKVLDRMALEVGQLVGIGVQVGLVIGGGNLFRGAALSAAGMDRVTGDHMGMLATVMNGLAMRDALERSNIPALVMSAISMVGVTDHYDRRKAIRHLNSGDVVIFSAGTGNPFFTTDSAACLRAIEIDADVVLKATKVDGVYTADPFKDPHAEKFDHLTYDEVLDRKLGVMDLTAICLCRDHKMPLRVFNMNKPGALLNIVVGGAEGTLIEEGQA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_SYNJA
Sequence: MSADEVYSRVRKIVSDQLGVEDDKVTLEANFQNDLGADSLDTVELVMAFEEEFDLEIPDEDAEGIATVQDAVNYILSKKAA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK23_NANDO
Sequence: MDGIKYAVFTDKSIRLLGNNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKGRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLSA_SINFN
Sequence: MPEQKAPQDLQLILDDIYRELTPRLGEGKVADYIPQLARVNPQHFGMAIVTTGGEVHRVGDAEVPFSIQSISKVFTLTLALGKHGENIWHRVGREPSGSAFNSIVQLEHEGGKPRNPFINAGAITISDLILAGHTPKELIGEIVRFVRYLADDENIVIDHEVARSETVTGFRNFALASFMRSFGRLDHPVEHVLGVYFHHCALAMTCSQLAKAGLFLAAGGTNPLTGHSVVSRQRARRINALMLTCGHYDGSGDFAYRVGLPGKSGVGGGIMAVAPGKASIAVWSPGLNENGNSLLGSLALEMLAARTGWSVFGP
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: NUOI_FRATF
Sequence: MRNITNFLKTFLLWELLKGLKVTGKHFFTRKVTVQYPDEKTPISNRFRGLHALRRYENGEERCIACKLCEVVCPALAITINSTEREDGTRRTSSYEIDLFKCIFCGYCEESCPVDSIVETNILEYHFEERGENIMTKAKLLAIGDKYEAQIAADRLQDKDFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIPX_MAIZE
Sequence: MAEITLEPSDLMAQTNKRIVPKFTEIFPVEDANYPYSAFIASVRKDVIKHCTDHKGIFQPVLPPEKKVPELWFYTELKTRTSSITLAIRMDNLYLVGFRTPGGVWWEFGKDGDTHLLGDNPRWLGFGGRYQDLIGNKGLETVTMGRAEMTRAVNDLAKKKKMATLEEEEVKMQMQMPEAADLAAAAAADPQADTKSKLVKLVVMVCEGLRFNTVSRTVDAGFNSQHGVTLTVTQGKQVQKWDRISKAAFEWADHPTAVIPDMQKLGIKDKNEAARIVALVKNQTTAAAATAASADNDDDEA
What is the function of this protein?
Potent catalytic inactivator of eukaryotic protein synthesis.  It may be a component of natural defense mechanisms involved in protecting the kernel against soil-borne fungal infections.
What are the official names of this protein?
Ribosome-inactivating protein, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: RLMF_SHIDS
Sequence: MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADHIHHLADLLAEASGTIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVTFIKKMIEESKGFAKQMMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIAO1_YEAS7
Sequence: MASINLIKSLKLYKEKIWSFDFSQGILATGSTDRKIKLVSVKDDDFTLIDVLDETAHKKAIRSVAWRPHTSLLAAGSFDSTVSIWAKEESADRTFEMDLLAIIEGHENEVKGVAWSNDGYYLATCSRDKSVWIWETDESGEEYECISVLQEHSQDVKHVIWHPSEALLASSSYDDTVRIWKDYDDDWECVAVLNGHEGTVWSSDFDKTEGVFRLCSGSDDSTVRVWKYMGDDEDDQQEWVCEAILPDVHKRQVYNVAWGFNGLIASVGADGVLAVYEEVDGEWKVFAKRALCHGVYEINVVKWLELNGKTILATGGDDGIVNFWSLEKAA
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Preferentially localized to the nucleus.
Protein: RPOZ_GRATL
Sequence: MDNQNIKIYNHLKVHEIIYKTEELLNISDNRYKITIQIANRAKRKKYEDLDIIDDPTIKPIIRSILEMVDEITQPEIISD
What is the function of this protein?
May be involved in RNA polymerase activity.
What are the official names of this protein?
Putative DNA-directed RNA polymerase subunit omega, PEP, Plastid-encoded RNA polymerase omega subunit, RNA polymerase omega subunit.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSRC_WOLSU
Sequence: MNQMWGSIEQYNTVVWHWPIAVYLFLAGLSAGAIISAIIIKWMKGNESSPWDGIIKAGALIAPLTIGAGLLLLIFDLTRPLHFWKLLIFYNFSSVMTLGVLALFAYFPVVLIFLLGVFKKELCDEGPFGFLAPLANIAYSMARPLEIVTFVLAIGVGAYTGFLLSAMYSYPLLNTPILPLLFLASGISAGISGNLLIGLLFFGKSTKGENVGYLHGLDFKVILFEAFLLFILFVGMYYQGGSTAEVAKAALTTGGLASLFWLGVAGMGLALPVVLNVALPHGIKHSSGFVMLNALIVLAGVMALRFYILYAGQTFVG
What is the function of this protein?
Component of the phosphorylative electron transport system with polysulfide as the terminal acceptor.
What are the official names of this protein?
Polysulfide reductase chain C, Sulfur reductase chain C.
What is the protein family that this protein belongs to?
Belongs to the NrfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MADD_HUMAN
Sequence: MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGCLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKEGTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSALLHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPESLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAEKLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQLAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPLTHAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGPGSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVHSSEEDLRTPPRPVSS
What is the function of this protein?
Guanyl-nucleotide exchange factor that regulates small GTPases of the Rab family (PubMed:20937701, PubMed:18559336).  Converts GDP-bound inactive form of RAB27A and RAB27B to the GTP-bound active forms (PubMed:20937701, PubMed:18559336).  Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms, GTPases involved in synaptic vesicle exocytosis and vesicle secretion (By similarity).  Plays a role in synaptic vesicle formation and in vesicle trafficking at the neuromuscular junction (By similarity).  Involved in up-regulating a post-docking step of synaptic exocytosis in central synapses (By similarity).  Probably by binding to the motor proteins KIF1B and KIF1A, mediates motor-dependent transport of GTP-RAB3A-positive vesicles to the presynaptic nerve terminals (By similarity).  Plays a role in TNFA-mediated activation of the MAPK pathway, including ERK1/2 (PubMed:32761064).  May link TNFRSF1A with MAP kinase activation (PubMed:9115275).  May be involved in the regulation of TNFA-induced apoptosis (PubMed:11577081, PubMed:32761064).
What are the official names of this protein?
MAP kinase-activating death domain protein, Differentially expressed in normal and neoplastic cells, Insulinoma glucagonoma clone 20, Rab3 GDP/GTP exchange factor, RabGEF, Rab3 GDP/GTP exchange protein, Rab3GEP.
What is the protein family that this protein belongs to?
Belongs to the MADD family.