PharMolix/UniProtQA huggingface dataset:
Protein: NSRR_YERP3
Sequence: MQLTSFTDYGLRALIYMASLPDGQMTSISQVTEVYGVSRNHMVKIINQLSRVGLVTAVRGKNGGIRLGKPADQILIGDVVRQMEPLTLVNCSSDFCHITPACRLKQVLNQAVQSFLKELDNYTLADMVKDNSPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: HISZ_HAHCH
Sequence: MSESDLWLLPDGVEELLPPEATRIEELRRQLLDLYHSWGYEMIVPPLLEFLDSLLIGVGRDLELEMFKVTDQLTGRLMGIRADMTPQVARIDSRRSHDVASRFCYIGSVLRTKSPSMFSSRTPIQTGCELYGVVGSAADIEIISLMLETLNLAKISPLHMDIAHVGVYQAILAEAKLSKIQSEELFEALRRKAIPEVDEIAATIPDKAIRQKVMALPRLAGGKEKMKEARKIFAGNPDIEYALDEMSQVAAVIGERYPEVEIYFDFCEMRGYKYYTGLVFAAYTEGLGQAVAKGGRYDEVGRDFGRGRPAMGFSVDLKALYRMGKREWAQPAGAILAPNGQDAELWELIRQLRRSNRVIQLMPGEEAGHWASHCDRQIVRDESGQWIVKPLTEFNPNHVK
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_VESOH
Sequence: MALNLMAKKAVVAQVNLLARVSVSIGVAEYCGLTVEQMTNLRSSAIDADVVLRVVKNSLAKRALVSTKCECVLPVLSGPVILGFSQQDLGAVARVFKNFIKENKDLVVKGLGVSGEFVESNQLKRIADLPTRDQAISIIMALMLAPVEKLARTLIEVPMKVTRVVEAVCDQKKS
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: LEF9_NPVOP
Sequence: MVSFLDRPPTEFDLILDPAKLNSAAFFSNDEFRAVLKSLIGDLKKNQRPNYFNSLVDQMINVYAHISAGEHADALVRIIDATCVVVTNLPSNVFLKKLKTNKFTDSIDYLILPHFILWDYNFVVFLNNTFNSKHENSLVDISGALQKIKLTHGVIKDQLQSKNGYAVQYSYSTFLNTASFYANVQCLNGVNEVMPPLHSVRRYFGRDVPHARAWTTRHPNISQLSTQVSDVRVNDRDTDWNVKVGLGIFPGANTDCDGDKKIITYLPRPNSLIDLECLLYGDPRYSFICFDKNRLTFVSQQIFYLHKNVEAVERLLKTMPLAFALWRIHANVKFSARLELLLRDFCLVASSNASYLLFKQLTELIKDEEMVCADEELFGLSGQFTDMVNSGAKGSAALIESTRQYARTRATDIDIVSTRATTSLNSYISSHNKVQVCGADIYHNTAVLQNLYIKNNYICYKNDDRRIASICALPSEYLFPEHLLDLFIE
What is the function of this protein?
Involved in late/very late gene activation.
What are the official names of this protein?
Late expression factor 9.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-9 family.
Protein: MICU1_HUMAN
Sequence: MFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEKKTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFDGKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKDMGFTRLMQAMWKCAQETAWDFALPKQ
What is the function of this protein?
Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains (PubMed:20693986, PubMed:23101630, PubMed:23747253, PubMed:24313810, PubMed:24332854, PubMed:24503055, PubMed:24560927, PubMed:26341627, PubMed:26903221, PubMed:27099988).  MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium.  MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake (PubMed:26903221).  Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening (PubMed:26903221).  Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm (PubMed:24560927, PubMed:26903221).  Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (PubMed:22904319).  Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG (PubMed:16002733).
What are the official names of this protein?
Calcium uptake protein 1, mitochondrial, Atopy-related autoantigen CALC, ara CALC, Calcium-binding atopy-related autoantigen 1.
What is the protein family that this protein belongs to?
Belongs to the MICU1 family. MICU1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space.
Protein: PP406_ARATH
Sequence: MSALSVIEQRLLKWDKLASLVPKSKKTPFPIDRLNELLKVCANSSYLRIGESIHAHLIVTNQSSRAEDAYQINSLINLYVKCRETVRARKLFDLMPERNVVSWCAMMKGYQNSGFDFEVLKLFKSMFFSGESRPNEFVATVVFKSCSNSGRIEEGKQFHGCFLKYGLISHEFVRNTLVYMYSLCSGNGEAIRVLDDLPYCDLSVFSSALSGYLECGAFKEGLDVLRKTANEDFVWNNLTYLSSLRLFSNLRDLNLALQVHSRMVRFGFNAEVEACGALINMYGKCGKVLYAQRVFDDTHAQNIFLNTTIMDAYFQDKSFEEALNLFSKMDTKEVPPNEYTFAILLNSIAELSLLKQGDLLHGLVLKSGYRNHVMVGNALVNMYAKSGSIEDARKAFSGMTFRDIVTWNTMISGCSHHGLGREALEAFDRMIFTGEIPNRITFIGVLQACSHIGFVEQGLHYFNQLMKKFDVQPDIQHYTCIVGLLSKAGMFKDAEDFMRTAPIEWDVVAWRTLLNACYVRRNYRLGKKVAEYAIEKYPNDSGVYVLLSNIHAKSREWEGVAKVRSLMNNRGVKKEPGVSWIGIRNQTHVFLAEDNQHPEITLIYAKVKEVMSKIKPLGYSPDVAGAFHDVDEEQREDNLSYHSEKLAVAYGLIKTPEKSPLYVTKNVRICDDCHSAIKLISKISKRYIVIRDSNRFHHFLDGQCSCCDYW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g39680, Protein EMBRYO DEFECTIVE 2744.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
Protein: GPN3_XENLA
Sequence: MPRYAQLVMGPAGSGKSTYCSTMVQHCETLNRSVQVVNLDPAAEHFDYPVLADIRELIEVDDVMEDRSLRFGPNGGLVYCMEYFANNFDWLESCLGHTEDDYILFDCPGQIELYTHLPVMKYLVEQLQQWEFRVCGVFLVDSQFMVESFKFLSGVLAALSAMVSLEIPQCNIMTKMDLLSKKAKKEIEKFLDPDMYSMIEDTPSRFKSTKFKKLTEALCGLVDDYSMVRFLPFDRSDEECMNIVLQHIDFAIQYGEDLEFKEPRENEEDKSENFDEYFQDRTDES
What is the function of this protein?
Small GTPase required for proper localization of RNA polymerase II (RNAPII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 3, ATP-binding domain 1 family member C.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: Y281_STRM5
Sequence: MPIHDWPEQERPREKLMARGPTALSDAELLALFLGSGFGGRDAVQTARDLLQAHGPLRVLLDRPARELARLPGLGPARSCTLAAGLELAHRYLAAELEHGEAVGNNPAAVGRYLQHRLRGQAREIFMALFLDNRHRLIACEELFHGTINAAPVYPREVVRRALLHNAAAVILSHNHPSGDPEPSSADTRITDELQQALAMVDVRLLDHFVVGEGRPVSFAERGLLSPPQPRLFG
What are the official names of this protein?
UPF0758 protein Smal_0281.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: YFCN_ECOLU
Sequence: MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPVKRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVDEWLPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: HTPG_ROSDO
Sequence: MTDASVKETFSFQTEVGQLLDIVAGSLYSNREIFLRELVSNASDACDKLRYEALTNPSLAQNADEFAISLAVDKKAKTLSVSDNGIGMNHGDLLDTLGTIARSGTGAFLDALKSEEKGDIGLIGQFGVGFYSAFMVAERVDVLTRKAGEDESWLWSSDGKGEFSIEPGERAQSGTTVTLHLKKDAKEFLEESRIRHIIKTYSEHISFPVRLDTEALNSASAIWTRAPKEITEEQHTEFYHHVSNAFDKPWHVLHNRVEGTVNHTSLLYVPSMAPFDLYEAERKSHVKLYVNRVFISDNTRDLIPAYLRFLRGVVDSQDLSLNVSREMLQSDPKLAKIKTSVTKKVLSELKKKAKKSPEDYAGFWQNFGPVLKEGLIEDPALRDRILEICRFSSTKSGDVTSLADYISRCKEGQDAIYYIAGDDARKIAQSPHLEGFRAKDVEVLLLSDHVDEFWLQHITEFEGKPFKSITRGAADLDKINEGEKADDAEEEAQAPDLNDLIAALKLELGASVKDVRPSKRLTDSPVCLIADEGDIDVNLERMLKRHGQLQDAMPRVLELNPDHRIITKLAERAKGSAAASDTLLKDAAHLLLDQARIADGETPADPAEFVRRLGSVMDSAL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDB_METB6
Sequence: MILVDWQLRDRIARGHIRIDPFDPALVQPNSIDIRLGNHFVWYAPGKQVIDPYDKTTVTSGVEGKHADFFDLLPGQFVLAETLECISLPDNIVATIEGKSSIARLGVTLHQTGGWIDAGFRGSITLEMANVNARPVRVYAGMPIGQLVFYTTERAENPYDKKADAKYLDQRQATLSKYHENRK
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ZNUC_SHIDS
Sequence: MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVKRFLRLRPGTHKEDILPALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFGPRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL35_CORA7
Sequence: MKQKTHKGTAKRIKVTGSGKLRREQANRRHLLEGKPSKRTRRLKGTEDVAKADTKRVKRLLGRA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: URE1_PARDP
Sequence: MGQTLSRADYAALYGPTTGDRIRLADTELLIEVERDLTIPGEEVRFGGGKVVRDGMGQSQVTREAGAMDTVITGAVVFDHQGITKADVGLRDGRIAGIGKAGNPDTQPGVTLIIGPGTEIIAGEGRILTPGGMDCHIHFICPQQVDHALHSGVTTLLGGGTGPAHGTLATTCTPGPWHIARMLEACAELPVNIGIAGKGNASLPAALEEQVRAGACALKLHEDWGTTPAAIDCCLTVADAMDVQVMIHTDTLNESGFVEDTMAAIAGRTIHAYHTEGAGGGHAPDIIRMVGMGNVLPSSTNPTRPYTGNTIEEHLDMLMVCHHLDRRVPEDVAFAESRIRRETIAAEDILHDLGAFSVISSDSQAMGRIGEVIIRTWQTADKMRRQRGRLAGETGENDNLRARRYIAKYTINPAIAHGISTHVGSIEPGKRADLVLWSPAFFGVKPEMVLVGGRISVAQMGDPNGSIPVQPIFSRPMWGHAGRASALFLSRAGLEAGAGDGLGKALIAVEQTRGIGKADMVLNDAMPQIEVDPETYEVRADGELLTCEPATELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2B_PSEAU
Sequence: NLIQFSNMIQCANKGSRPSLDYADYGCYCGWGGSGTPVDELDRCCKVHDDCYAEAGKKGCYPKLTLYSWDCTGNVPICNPKTECKDFTCACDAEAAKCFAKAPYKKENWNIDTKTRCK
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 PA-5, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPA_RHIWR
Sequence: MSEPLPITDAPKQRKPDWIRVKAPMGQAFSDTKALMRRLNLATVCEEAACPNIGECWTKKHATVMILGDTCTRACAFCNVKTGMPRPVDALEPQHVADAAAELGLEHIVVTSVDRDDLPDGGAKQFVKVIEALRRTTPRTTIEILTPDFRNKADAAIEMIVAARPDVYNHNLETVPRLYPTIRPGARYYASLRLLETVKRLDPTIFTKSGIMVGLGEERLEVHQVMDDMRSADIDFLTMGQYLQPTPKHAKVADFVAPKTFEAYAAIARAKGFLLVAATPLTRSSYHAGDDFVKLRDARNAELARKAAVPAA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGAS_STRMB
Sequence: MRIRRRALVFATMSAVLCTAGFMPSAGEAAADNGAGEETKSYAETYRLTADDVANINALNESAPAASSAGPSFRAPDSDDRVTPPAEPLDRMPDPYRPSYGRAETVVNNYIRKWQQVYSHRDGRKQQMTEEQREWLSYGCVGVTWVNSGQYPTNRLAFASFDEDRFKNELKNGRPRSGETRAEFEGRVAKESFDEEKGFQRAREVASVMNRALENAHDESAYLDNLKKELANGNDALRNEDARSPFYSALRNTPSFKERNGGNHDPSRMKAVIYSKHFWSGQDRSSSADKRKYGDPDAFRPAPGTGLVDMSRDRNIPRSPTSPGEGFVNFDYGWFGAQTEADADKTVWTHGNHYHAPNGSLGAMHVYESKFRNWSEGYSDFDRGAYVITFIPKSWNTAPDKVKQGWP
What is the function of this protein?
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase, MTG, Transglutaminase, TGase.
What is the protein family that this protein belongs to?
Belongs to the bacterial TGase family.
Protein: CM39_CONRE
Sequence: LLFPLSALPLDGDQPADQPAERMQDISPEQNFWFDLVERGCCTIWNCVQLPGCPCC
What are the official names of this protein?
Conotoxin reg3.9, Rg3.9.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMM_RHIEC
Sequence: MKRRYFGTDGIRGQSNVFPMTPDLAMRVGIAAGTIFRRGNHRHRVVIGKDTRLSGYMLENAMVAGFTAAGLDAFILGPIPTPAVAMLTRSLRCDIGVMISASHNPYEDNGIKLFGPDGYKLSDDIEAEIEDLLEKDLNAQLAKSDDIGRAKRVDGVHDRYIEHAKRTLPRDVTLQGLRVAIDCANGAAYKVAPAVLWELGADVVTIGNEPNGTNINLNCGSTSPVALQKKVDEVRADIGIALDGDADRVIIIDENGSIVDGDQLMAVIAESWAESQQLRGNGIVATVMSNLGLERFLDERGMALARTKVGDRYVVEHMRQHNYNVGGEQSGHIVLSDYGTTGDGLVAALQILAAVKRTGRTVSEVCRRFEPVPQLLRNVRISGGKPLEDIQVQKAIADAEAELARNGRLVIRPSGTEPLIRVMAEGDDRAQIERIVNELIGTISNVRTAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: H2A3_ORYSJ
Sequence: MAGRGKAIGSSAAKKATSRSSKAGLQFPVGRIARFLKAGKYAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIVPRHIQLAVRNDEELSRLLGAVTIANGGVMPNIHNLLLPKKAGSSAKAAAADDE
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2A.3.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SNAT_MOUSE
Sequence: MLNINSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEDALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC
What is the function of this protein?
Controls the night/day rhythm of melatonin production in the pineal gland.  Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
What are the official names of this protein?
Serotonin N-acetyltransferase, Serotonin acetylase, Aralkylamine N-acetyltransferase, AA-NAT.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. AANAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_RUEST
Sequence: MTASAPITQDVLTLPRKEPEGGKINLVGLTRDRMRAVLIENGTPEKQAKMRVGQIWQWIYQWGVRDFAEMTNLAKAYRAQLEETFEIRIPEVVSKQVSTDGTRKYLVRINGGHEVEVVYIPEDDRGTLCISSQVGCTLTCSFCHTGTQKLVRNLTPAEIIGQVMMARDDLEEWPTPGAPKDETRLLSNIVLMGMGEPLYNFDNVRDAMKIAMDPEGISLSRRRITLSTSGVVPEIARTAEEIGCLLAISFHATTNEVRDVLVPINRRWNIDELLQALADYPKVSNSERITFEYVMLDGVNDSDEDAHRLLDHIKRHNIPAKINLIPFNEWPGAPYKRSSNNRIRAFANIIYQAGYASPIRKTRGDDIMAACGQLKSATERARKSRKQIEAEAGVNNS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_CUTAK
Sequence: MSIPKSTPDRRVTRVMGVDPGLTRCGVGVVEGGLGSSLKLIAVGVIRTPADLDHAHRLLRIHDGLEEWRDHTRPDAIAVEKVFAQHNRNTVAGTAQAAGIAMMIAARHGLPVALHTPSEVKAAISGSGRADKAQVGFMVARVLRLSAPPKPADAADAVALAICHLWRGGAARRIEAAVATQRRGRRVPRSWKDLAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TAL_CAUVN
Sequence: MQIFLDSTDTKVIADLASTGLIDGVTTNPTLIAKSGRPMLEVIAEICDIVPGPISAEVAATTADAMIAEGQKLAKIAPNVVVKIPLTRDGLIACAAFADEEIKTNVTLCFSPTQALLAAKAGATYISPFIGRLDDYGFDGMDLIRDIRAIYDNYGYETEILAASVRNAAHVKEAAIVGADVVTIPPAVFSDLYKHPLTDKGLEQFLKDWASTGQSIL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFM7_SCHPO
Sequence: MADNDFEGFGIFEEPEGFRPSTPPPKEVLHTRVIVPNGPEEIKLRLVGSHSLWAHYLWNSGIELANYIDKNPDTVRAKKVLELGAGAGLPSIVSAFDGAKFVVSTDYPDPALIDNLEHNVKQYAEIASKISAVGYLWGSNIKEVMSNAGFKDNEVFDILLLSDLVFNHTEHSKLIKSCKMAIEGNPNAVVYVFFTHHRPHLAKKDMIFFDIAQSEGFQIEKILEEKRTPMFEEDPGAPEIRATVHGYKMTIPIPV
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
What are the official names of this protein?
Protein N-terminal and lysine N-methyltransferase efm7, Elongation factor methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUC_WOLTR
Sequence: MSHESIEKNLNFVKKLNNVNDSVLKIENLALAYDNKKVLDGINISIEKGDIVTILGPNGGGKTSLMKVVAGISKNYTGSVIFADNIKISYMPQNFSISKLMPITVEYFLLNSFSKKLKKNQSVITEVIELVGIGSILKNQVLEISAGQMQLLLLAHCLIAEPDLIILDEPVSAMDINARAKFYDIIGEIAKKRLISILMTSHDLSSIVPCSDYIICINHTIYCQGKPGKIMEDRTLGEIFSSYIAK
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OBG_STRGR
Sequence: MTTFVDRVELHAAAGNGGHGCASVHREKFKPLGGPDGGNGGRGGDVILVVEQSVTTLLDYHHSPHRKATNGQPGAGDNRSGKDGQDLVLPVPDGTVVLDKAGNVLADLVGQGTTFVAGQGGRGGLGNAALASARRKAPGFALLGEPGESRDIVLELKTVADVALVGYPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVTAGSTVYTIADVPGLIPGASQGKGLGLEFLRHVERCSVLVHVLDTATLESDRDPVSDLDMIEEELRLYGGLENRPRIVALNKVDIPDGQDLADMIRPDLEARGYRVFEVSAIAHKGLKELSFALAGIIAEARATKPKEEATRIVIRPRAVDDAGFTVTLEDDGIYRVRGEKPERWVRQTDFNNDEAVGYLADRLNRLGVEDSLMKAGARAGDGVAIGPEENAVVFDWEPTVTAGAEMLGRRGEDHRLEEPRPAAQRRRERDAERDDAEKEYDEFDPF
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODF_AQUAE
Sequence: MGVHKIQPKDHLKPQNLEGISNEQIEPHFEAHYKGYVAKYNEIQEKLADQNFADRSKANQNYSEYRELKVEETFNYMGVVLHELYFGMLAPGGKGEPSEALKKKIEEDLGGLDACTNELKAAAIAFRGWAILGLDIFSGRLVVNGLDAHNVYNLTGLIPLIVIDTYEHAYYVDYKNKRPPYIDAFFKNINWDVVNERFEKAMKAYEALKDFIK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: HIS7_CALBD
Sequence: MGQRVAEVQRKTKETDIKLILNIDGNGDYKISTGIGFFDHMLQLFSHHGKFDIDLEAKGDIYIDDHHTIEDVGIVLGQAFLKALSDKRGIKRYAHVILPMDEALIMVAVDISGRPYLAFDVDFKLPKLGDMTSQMVVEFFKAFVWSSKTTVHIKKLAGENDHHVCEAIFKAIGRTLKEACTIIDDRIPSSKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATA_ONCVE
Sequence: MSQNKTLTTASGPPVADNQNSRSAGPRGPLLLDDFHLIEKLAHFNRENIPERRVHAKGSGAYGTFTVTQDITQYTSAKLFDSVGKQTPTFLRFSTVGGERGSADTERDPRGFALKFYTEEGNWDIVGNNTPVFFIRDPLKFPDFIHTQKRLPQSNLKSAQMMWDFWSHSPEALHQVTILFSDRGIPDGYRHMHGFGSHTYSLINAKGERHWVKWHYKTKQGIKNLAPADAARLAGTDPDYAQRDLFGAIERGDFPKWRVCIQIMTEAQANAHYENPFDVTKTWSQKEFPLIEVGELELNRNPLNYFAEVEQAAFGPSNMVPGVGLSPDRMLQGRVFAYADAHRYRVGTNHQQLPVNAPRSPVNSYQRDGSMAFGSNGGAAPNYEPNSYADAPKQAPQYAEPALALSGAADRYDHREDTDYYSHAGALFRLMNDEQKALLINNIAGAMAGVSSDVVQRQLQYFFKADPAYGEGIASALGVSLN
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.