PharMolix/UniProtQA huggingface dataset:
Protein: COBS_CORGL
Sequence: MSGKAGFTPEDPEDSDNRHGNPLFEGIFTALNWMTVLPVPGASVFDRTTGARVMASLPFVGFVFGMFTAIIMWAIGPISGVIHVDGLLVAVLIVAFWELLNRFMHLDGLADVSDALGSYAAPPRAREILADPRTGLFGLATAMLSVLLQVAAVASLVDSTVWWMICFIPVLGRIAGQVTALKNHNAFSPTGFGALVIGTVKFWWIALWLLVTAALAFWCAELISPLSPLTSVNTPFVAGPFPAAINPAWLGGWVAITAVVACVFAALFSRRLSRSFGGLNGDCIGACIHLGASISAVMFAVVANAMV
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAD_CAMJD
Sequence: MTCLYPGTFDPITNGHLDVIKRALKIFDEVIVAIAKSEHKKPCYDLEKRKELALLATQNLKNVKIIAFDNLLVDLAKELKVNTIIRGLRAVSDFEYELQIGYANHALWEDMETIYLMPSLKHAFISSSIVRSIVAHGGDVSSLVPKEILPFLKDQSCM
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUNA_BUTFI
Sequence: MVSKKQKFLTVILVIVLAIVIVGGVFGISFVKGRVTFPWQLQNSEAKTEQVKEPAKEEPKLVIKEKKQDESAKKEQELKKAKEEAEAAVEKETEKTEEEPVDNLLNDMKLKYYGKLAVEGSHLVDADGHEVLLMGVSTHGINWYPEYASAETIKSLRDTWGINVIRLAMYTSDYNGYCVAGKENQEKLKDIIDDAVEAATDNDMYVIIDWHTLNDADPNEYKADAIQFFGEMVRKYKDNENVIYEICNEPNGDTTWNDVRRYANEVIPVIRNVDAIILVGTPKWATDLDSVLDKPLDFDNIMYTYHFYAGTHHKAERNALRDALDEGLPVFISEYGLVDADGDGNLNEKEADYWYDMIRKEYGVSSCMWNLSNKDEGSAMINADCDKLSDFTEEDLSESAMWLIDQISQLKHSDLEQGVDWITPENNNR
What are the official names of this protein?
Endoglucanase A, Cellulase A, Endo-1,4-beta-glucanase A, EgA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: SYR_LEUMM
Sequence: MVDNIQIVEALNAVLTDLTLQEISEKLEAPKSSDLGDVAFPTFTLAKTLHKAPQLIAADIVAAIDQEGFEKVVATGPYVNFFLDKVATSNQVLKTVFDLEGAYGDNVDGQGAKVTIDMSSPNIAKPMSMGHLRSTVIGNALANITAKNGYAPVKINHLGDWGTQFGKLIYAYKAWGSEEEVKSDPIATLLKYYVEFHEKAKENDSLNDEGRAWFKKLEDGDEEAHRLWQWFRAESLKEFSEIYDRLDITFDSFNGEAFYNDKMDKVVDLLEEKNLLVESQGAQIVDLSHINPNLTPAMIKRSDGATLYMTRDLAAALYRKETYDFAKSLYVVGGEQREHFVQMKAVLSLMGFEWSDDIEHIAFGLITFNGKKMSTRKGDVVLLKDVLDDAHELALKQIQEKNPDLGDKDTVAEEVGAGAVVFHDLMNDRTNNFDFNLEEVVRFEGDTGPYVQYTNARAKSILRKTSVQLTSDDLNLTDPATWDIITTLNNFPKTVQRAWQQREASIIAKYALNLSRAFNKYYANSKILTEDVQLNARLVLVKSVSIVLTESLRLLGVKAPEEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPA_METJA
Sequence: MIGDYERFKQLKKKVAEALNISEEELDRMIDKKIEENGGIILKDAALMMIAKEHGVYGEEKNDEEFLISDIEEGQIGVEITGVITDISEIKTFKRRDGSLGKYKRITIADKSGTIRMTLWDDLAELDVKVGDVIKIERARARKWRNNLELSSTSETKIKKLENYEGELPEIKDTYNIGELSPGMTATFEGEVISALPIKEFKRADGSIGKLKSFIVRDETGSIRVTLWDNLTDIDVGRGDYVRVRGYIREGYYGGLECTANYVEILKKGEKIESEEVNIEDLTKYEDGELVSVKGRVIAISNKKSVDLDGEIAKVQDIILDNGTGRVRVSFWRGKTALLENIKEGDLVRITNCRVKTFYDREGNKRTDLVATLETEVIKDENIEAPEYELKYCKIEDIYNRDVDWNDINLIAQVVEDYGVNEIEFEDKVRKVRNLLLEDGTGRIRLSLWDDLAEIEIKEGDIVEILHAYAKERGDYIDLVIGKYGRIIINPEGVEIKTNRKFIADIEDGETVEVRGAVVKILSDTLFLYLCPNCRKRVVEIDGIYNCPICGDVEPEEILRLNFVVDDGTGTLLCRAYDRRVEKMLKMNREELKNLTIEMVEDEILGEEFVLYGNVRVENDELIMVVRRVNDVDVEKEIRILEEME
What is the function of this protein?
Probably plays an essential for replication of the chromosome, DNA recombination and repair (By similarity).  Binds approximately 20 nucleotides.
What are the official names of this protein?
Replication factor A, RF-A, RP-A, Replication factor A protein 1, Replication protein A, Single-stranded DNA-binding protein, mjaSSB.
Protein: AAT_PYRAB
Sequence: MAMSDRLDLVNPSEIRKLFDIAAGMKDVISLGIGEPDFDTPQHIKEYAKEALDMGLTHYGPNIGLPELREAIAEKLKKQNNIEADPNKEIMVLVGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAPAVILAGGKPVEVPTYEENEFRLNVDELKKYVTEKTKALIINSPCNPTGSVLKKKDLEEIADFAVEHDLIVISDEVYEHFIYDDVKHYSIASLDGMFERTITVNGFSKTFAMTGWRLGFVAAPSWIIEKMVKFQMYNATCPVTFIQYAAAKALRDERSWKAVEEMRKEYDRRRKLVWKRLNEMGLPTVKPKGAFYIFPRIKDTGLTSKEFSELMLMEAKVAVVPGSAFGKAGEGYVRISYATAYEKLEEAMDRMEKVLREKKLT
What are the official names of this protein?
Aspartate aminotransferase, AspAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT2_CLOB1
Sequence: MKLLEDKILKEGILLEGNILKVDSFLNHQMDVKLFNEIGKEFKRRFEGCSINKILTIEASGIGIATIVSQYFDFCPVVFAKKVDAANMDKDTYESKVHSFTKNKTYNVRVSKKYINKGDKILLIDDFLANGCAALGLIDIIKQGGAELIGVGIAIEKGFQKGRKELEKVGAKVESLAILDKIENDKVYFK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase 2, XPRTase 2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_SACD2
Sequence: MTAEATVETRGFETEAKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALKQPELLEQDSELKITIDFDKEAKTLSITDNGIGMNRDEVIANLGTIARSGTAQFMANLSGDQKKDSQLIGQFGVGFYSAFIVADKVEVLTRRAGSEPSEGVRWVSEGEAEYSIENIEKAARGTTIILHLKKDQEEFADGWRLRSIIKKYSDHISLPVEMPKEAAPGEDKEEKAEVEYEVINTAKALWARSRSDVTDEEYKEFYKHVSHDYTDPLSWSHNRVEGKLDYTSLIYIPSKAPFDMYNREKPRGVKLYVQRTFIMDDAEQFLPLYLRFIKGVVDSNDLSLNVSREILQQDPNIDSMRSALTKRVLDMLEKMAKKEPEKYATFWKEFGEVLKEGPAEDFANKEKIAKLLRFATTHKNTNEQDQSLDAYIERMKEGQDKIYYVVAENFNTAKNSPHLEVFRKKGIEVLLLSNRIDDWLMGHLMEYDGKQFQDVGKGSLDLGKLDSEEDKKEQEKVEEAMAPFVERMKAALAEQVEEVRITHRLTESPACLVVGEHDMGAQMRRLLEAAGQAVPESKPIIEINPTHPLVQKLDQEQDEDRFKDLSHILFDQASLAEGGSLKDPAAYVSRLNKLLLELSN
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US02_HHV2H
Sequence: MGVVVVSVVTLLDQRNALPRTSADASPALWSFLLRQCRILASEPLGTPVVVRPANLRRLAEPLMDLPKFTRPIVRTRSCRCPPNTTTGLFAEDDPLESIEILDAPACFRLLHQERPGPHRLYHLWVVGAADLCVPFFEYAQKTRLGFRFIATKTNDAWVGEPWPLPDRFLPERTVSWTPFPAAPNHPLENLLSRYEYQYGVVVPGDRERSCLRWLRSLVAPHNKPRPASSRPHPATHPTQRPCFTCMGRPEIPDEPSWQTGDDDPQNPGPPLAVGDEWPPSSHVCYPITNL
What is the function of this protein?
Plays a role in the activation of the host NF-kappa-B pathway by interacting with and thus activating the component MAP3K7.
What are the official names of this protein?
Protein US2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HHV-1 US2 protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host cell surface. Host nucleus. Note=Found in association with the nuclear matrix of infected cells.
Protein: END4_YERPG
Sequence: MKFVGAHVSAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVIEKFKLACEKYGYTSAQILPHDSYLINLGHPVTEALEKSREAFIDELVRCQQLGLSLLNFHPGSHLLQIDEDQCLARIAESINIALDATEGVTAVIENTAGQGSNLGFKFEHLAAIIERVEDKSRVGVCIDTCHAFAAGYDLRTEEDCEHTFAALGKIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMRDSRFDNIPLILETVNMDIWAEEIAWLKSQAEIEPSL
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RPO10_PYRFU
Sequence: MIVPVRCFTCGKVIGDKYYEFKRRVEAGEDPEKVLDDLGLERYCCRRMLLSHVELIDDIMHYRVY
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_STRPG
Sequence: MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDHQKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALGTDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGLKIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELDVLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADSLVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MENG_STAAT
Sequence: MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKLVHGDAMELPFEDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLPVFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKGD
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: EFTU_ANADE
Sequence: MAKEKFERSKPHVNVGTIGHVDHGKTTLTAAITKVLAQKGGAQFLAYDQIDKAPEERERGITIATAHVEYQTEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIVVFLNKVDMVDDKELLDLVELEVRELLSEYDFPGNEIPIVKGSALKALEGDKGELGEQAIFKLMEAVDAYIPTPQRATDKPFLMPVEDVFSISGRGTVATGRVERGIVKVGEEVEVVGLKATAKTVVTGVEMFRKLLDEGRAGDNIGALLRGLKREEVERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNGYRPQFYFRTTDVTGSVQLPQGVEMVMPGDNIGMEVELITPIAMEKELRFAIREGGRTVGAGVVAEVIQ
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFT43_BOVIN
Sequence: MEDLLDLGEERRRCPATSGAKMGRRAQQESTQAENHLSGKNSSLTLTAEVPPPKPPRRQGRWAEASVKVSKSQRRASEEIQDHRLRQQSLDRSDDGGDIPVIPDLEEVQEEDFVLQVAAPPSIQVNRVMTYRDLDNDLMKYSAFQTLDGEIDLKLLTKVLAPEHEVREDDVSWDWDHLYTEVSSELLSEWDALQTEKEGPVGQPAHT
What is the function of this protein?
As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis.  Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base.
What are the official names of this protein?
Intraflagellar transport protein 43 homolog.
What is the protein family that this protein belongs to?
Belongs to the IFT43 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Note=Associated with microtubules. Localized at the distal tip of the cilium.
Protein: BOP1_CAEEL
Sequence: MASTSAATPLKNKRKFENGKKKPKTLKDEFGEKLDIKPVIVPPKPADEYDYDSSDEEDLRNTIGNIPIKWYDDEDHIGYDKFGEKIAKPAKKGEIETFLEKMEDPDYWRKVFDKQTGTDVKLTDEQIEKIHNIATGKYPTIGYNPYEPFLDIFSSQKEIHPIDNRPEPKSRFIPSKDEMRMVSRMVHAIKMGWAKGPRAKKEEHKSYDLWASEDALDNVTKSQLSRMRVHMPAPKVALPTHAESYNPPEEYIFDDEERKKWEEAEKEDRVLNFMPSKYDALRKVPQYDKFITERFERCLDLYLAPRQRKMRIHADPTDLLPDLPNPNDLRPFPTTLAFYMRGHTGQVRAITVEPERGELLASGGEDGTVRIWMIATGRCIKTFQMDGEVTSVSFSPVADRTLLAVAYEGKYVAILNTGCGDRLHVQQTEALLAETPTDAQEDGAVVTWRKSKEKLMLKMPNEVRQVTWHSKGDYFASVAIDDIAKSVYVHQLSKAKSQCPFQKRKGHVQAVTFHPTQARLFVATKIHVREYDLARCVLVKKLITGCKHISTMATDANGENLFLGGLDRRFCWMDLQMGNKPWKKLKHHTAAVRSVAYHKKYPLLATVSDDGTAMVYYARIYTDFVKDNELYPVKRLRAHEKTPNDLCMLHTTWHPTQPWLITAGADGTIALFTY
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: SYDND_BURCJ
Sequence: MSMRTEYCGLVTEHLLGQTVSLCGWVQRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFATAEGVRNEFCVQIKGLVRNRPEGTVNAGLKSGKIEVLCHELNVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFIDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETSFLGEQEIRDLFEDMIRHIFKTTIDVELDAKFPVMPYSEAMARFGSDKPDLRVQLEFTELTDAMKDVDFKVFSTPANAKDGRVAALRVPKGGELSRGDIDGYTEFVRIYGAKGLAWIKVNEKAKGRDGLQSPIVKNLHDASIAAILERTGAEDGDIIFFAADRAKVVNDSLGALRLKIGHSEFGKANGLVQAGWKPLWVVDFPMFEYDDEDARYVAAHHPFTSPKDEHLEYLETDPGRCLAKAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGAEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDVIAFPKTQRAQDLLTQAPSPVDERQLRELHIRLRQPEQPKA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_DESPS
Sequence: MTEQKSKKLWGGRFSEAMAASVEKFSESISYDVRLYKYDIAGSKAHATMLSSQGIISPEELEQIIAGLSSIEADIEAGVFEFKTEYEDVHMNIEQALVDRIGAAGSRLHAARSRNDQIALDFKMYLRDQCDHLVELLDGACRAFTVVGRKYLGDIMPGYTHTQRAQPVLITHHMLAYYEMFRRDRDRILDCRKRLNLSPLGCAAMAGTGLPINREQVAKALGFAGVTANSMDTSADRDYAIELTSCLTMIQLHLSRLAEELVTWSTSEYKFVDISDSFCTGSSIMPQKKNPDIAELIRGKSGRVVGSLISLITMMKGLPLTYNRDQQEDKEPVFDAIDTVSASLSITAEMMAHMKFNTARCAEATETGFITATDLADYLVMKDVPFRQAHHIVGSAVAACIAKGCELPDLTLTEMQEFSPVIESDVFAVLTAEGSVNSRVSTGGTGLVRVTEALTLAEKCVGIA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBR_RICCO
Sequence: MEDMKPSTASTKNLHHDGVGENDTIEVRFTDFCKIGLSVSEDAYEEAIKLFKGTKHLLLANISAIGNGMPEEAERFWFAFVSYSVKRLSEKIRDNMQQRPDDNGLTLCQILRRAKLNIVDFFKELPQYVVKAGPILSTMYGVDWENRLEAKELQANFVHLSILSRHYKRAYRELFLTSDANVDKQSATAYMSDYHRFGWLLFLALRVHAFSRFKDLVTCTNGLVSVLAILIIHVPVRFRNFNLNDSQRFVKKGDKGVDLLASLCNKYDTSEDELRKTMEKTNNLIADILKKKPHMASEYKNENLDNINTDGLIYYEDLMEESSLRSSLDILEKDYEDAIRCKGELDERVFINEEDSLLGSGSLSGGAISVTGTKRKFDQISSPTKTITSPLSPHRSPASHTNGILGSTNSRMAATPVSTAMTTAKWLRTVISPLPSKPSPQLERFLASCDRDVTNDVIRRAHIILEAIFPSNALGERCVTGSLQSTNLMDNIWAEQRRLEALKLYYRVLEAMCTAEAQILHATNLTSLLTNERFHRCMLACSAELVLATHKTVTMLFPAVLERTGITAFDLSKVIESFIRHEESLPRELRRHLNSLEERLLESMVWEKGSSMYNSLTVARPSLSAEINRLGLLAEPMPSLDAIAVHINFSSGGLPPLSSVSKHEISPGQNGDIRSPKRPCTDYRSVLVERNSFTSPVKDRLLAFTNLKSKLPPPPLQSAFASPTRPNPGGGGETCAETGINIFFSKINKLAAVRINGMVERLQQSQQHIRENVYRLFQQVLSQQTSLFFNRHIDQIILCCFYGVAKISKVNLTFREIIYNYRKQPQCKPQVFRSVFVDWSSARHNGRTGQDHVDIITFYNEIFIPAAKPLLVEVGSAGITVKGSQVPEVNNNKDGQCPASPKVSPFPSLPDMSPKKVSAAHNVYVSPLRTSKMDALISHSSKSYYACVGESTHAYQSPSKDLTAINNRLNGNRNIRGSLNFDDVDVGLVSDSMVAKSLYLQNGSCASTSGAPLKTEQPDP
What is the function of this protein?
Regulator of biological processes that recruits a histone deacetylase to control gene transcription.  May play a role in the entry into mitosis, negatively regulating the cell proliferation.  Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).
What are the official names of this protein?
Retinoblastoma-related protein.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 14332_PSEMZ
Sequence: LAEQAERYEEMVEYMEKNLLSVAYKIISSIEQKEESRQAFDEAIAELDTLGEESYKDSTLIMQLLR
What are the official names of this protein?
14-3-3-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: PCP_STRPQ
Sequence: MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVFQKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPIRVDGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAKAGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2_I77AA
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRLFKHGLKRGPSTEGVPESMREEYRKEQQNAVDADDSHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: HEM3_NITEU
Sequence: MSSPKKIVIASRESQLALWQANFIRGRLLELYPQTDITILGMTTKGDQILDVSLSKIGGKGLFIKELELALEDGRADIAVHSMKDVPMIVPSGFTLAAITEREDPRDAFVSNDFSSLEELPAGSVVGTSSLRRESQLRARFPHLQVRPLRGNVQTRLRKLDEGEYSAIILAAAGLKRLELGYRISMLLPPELSLPAVGQGALGIECRDNDPDMVEWMKPLHHAATACCVEAERAMSRMLGGSCQVPLGGFAEIFEDVLTLRGFVATPDGSRMIADKLCGKPESGEQVGQQLAQNLKAHGAEEILAALA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ARLY_RHOJR
Sequence: MSAHGTNEGALWGGRFESGPAAAMAALSKSTHFDWVLAPYDVRASQAHARVLHKAGLLGDEDLASMLDGLGRLAADVASGEFVPSESDEDVHGALERGLIDRVGPEVGGRLRAGRSRNDQVATLFRMWLRDAVRRVAAGVLDVVDALATQAAAHPSAVMPGKTHLQAAQPVLLAHHLLAHTHPLLRDVQRLRDFDVRAAVSPYGSGALAGSSLGLDPEAIAAELDFDSSAENSIDATSSRDFAAEAAFVLAMIGVDLSRMAEEVILWSTPEFGYITLADAWSTGSSIMPQKKNPDVSELTRGKSGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAITGLVSTLEFHTDRMAELAPAGFTLATDIAEWLVRQGVPFRVAHEAAGACVRVAEARGVGLEDLTDDELAGVDPALTPDVREVLTVEGSIASRNARGGTAGIRVAEQLGGVRQLSESLREWCR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_MOOTA
Sequence: MIKAGIIGATGYTGAELVRILSRHPEVELVALTSRSYAGEGMAGVYPSLTGYTNLTCENLTPDEVMDRAEVIFIALPHGHAVPVATRARERGIKVIDLGADWRFRNARTYEEWYKIQHGNHELAARAVYGLPEIHREAIRSAGLVANPGCYPTSAILGLAPLLKGGYIDPATIIIDAKSGVSGAGREARVTSLFVECNESINPYGVASHRHTPEIEQELSALAGKEVKVTFTPHLLPISRGILSTMYATLVRPASTEELRRVYEKFYAGEPFVHLLPPGQWPHTRWVYGSNNCHLNLAVDTRTGRVVVASAIDNLTKGASGQAVQNLNLMCGFPETMALEVPGLCP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_ANADE
Sequence: MFGLRMPELLLILAIVVILFGASRLPALGAGLGQGIRSFKKAFGGEDEKPTASGNGSTPTQSSSDQGSKQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YMF07_MARPO
Sequence: MGYGCRNKYTGVHLAGSCKQIKTYQVGIQRNIIWVITSFFLISSSFSRNGSLNSSAYFIFLFFNIVTKFIKIESCFLFYAVRKVAN
What are the official names of this protein?
Uncharacterized mitochondrial protein ymf7, ORF86B.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CEP41_CHICK
Sequence: MSSRRSVGDPEYLTRRIPQNPRYQHIKTRLDTGSSLTKYIEKLEEIKRNYRYRKDELFKRLKVTTFAQLVVQVASLSDETLEVTNEEIHKLEGGNSPASDADAELTAGTNGKGSPNGTPPSPVLFINNAGAGESYRSTLQSLISGVGELDIEKDTHKKADTQAKDTPYPDCPFLLLDVRDRDAYDQCHIVGAYSYPIAMLSRAMNPYTNSILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKVPEGLITGSLPISCQVAAPTGSARKKPVPKVPPTRAESKWRYSAEDLQKIKYYLEEEQLPSDTASRLSRGSSGRDSKATTARSSPSLPSTAGSRMLSRSSIQNRPWK
What is the function of this protein?
Required during ciliogenesis for tubulin glutamylation in cilium.  Probably acts by participating in the transport of tubulin polyglutamylases between the basal body and the cilium (By similarity).
What are the official names of this protein?
Centrosomal protein of 41 kDa, Cep41.
What is the protein family that this protein belongs to?
Belongs to the CEP41 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes mainly to the cilium basal body and in primary cilia.