PharMolix/UniProtQA huggingface dataset:
Protein: MARK4_HUMAN
Sequence: MSSRTVLAPGNDRNSDTHGTLGSGRSSDKGPSWSSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPGLALARVRAPSDTTNGTSSSKGTSHSKGQRSSSSTYHRQRRHSDFCGPSPAPLHPKRSPTSTGEAELKEERLPGRKASCSTAGSGSRGLPPSSPMVSSAHNPNKAEIPERRKDSTSTPNNLPPSMMTRRNTYVCTERPGAERPSLLPNGKENSSGTPRVPPASPSSHSLAPPSGERSRLARGSTIRSTFHGGQVRDRRAGGGGGGGVQNGPPASPTLAHEAAPLPAGRPRPTTNLFTKLTSKLTRRVADEPERIGGPEVTSCHLPWDQTETAPRLLRFPWSVKLTSSRPPEALMAALRQATAAARCRCRQPQPFLLACLHGGAGGPEPLSHFEVEVCQLPRPGLRGVLFRRVAGTALAFRTLVTRISNDLEL
What is the function of this protein?
Serine/threonine-protein kinase (PubMed:15009667, PubMed:14594945, PubMed:23666762, PubMed:23184942).  Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:14594945, PubMed:23666762).  Also phosphorylates the microtubule-associated proteins MAP2 and MAP4 (PubMed:14594945).  Involved in regulation of the microtubule network, causing reorganization of microtubules into bundles (PubMed:14594945, PubMed:25123532).  Required for the initiation of axoneme extension during cilium assembly (PubMed:23400999).  Regulates the centrosomal location of ODF2 and phosphorylates ODF2 in vitro (PubMed:23400999).  Plays a role in cell cycle progression, specifically in the G1/S checkpoint (PubMed:25123532).  Reduces neuronal cell survival (PubMed:15009667).  Plays a role in energy homeostasis by regulating satiety and metabolic rate (By similarity).  Promotes adipogenesis by activating JNK1 and inhibiting the p38MAPK pathway, and triggers apoptosis by activating the JNK1 pathway (By similarity).  Phosphorylates mTORC1 complex member RPTOR and acts as a negative regulator of the mTORC1 complex, probably due to disruption of the interaction between phosphorylated RPTOR and the RRAGA/RRAGC heterodimer which is required for mTORC1 activation (PubMed:23184942).  Involved in NLRP3 positioning along microtubules by mediating NLRP3 recruitment to microtubule organizing center (MTOC) upon inflammasome activation (PubMed:28656979).
What are the official names of this protein?
MAP/microtubule affinity-regulating kinase 4, MAP/microtubule affinity-regulating kinase-like 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm. Cell projection, dendrite. Note=Localized at the tips of neurite-like processes in differentiated neuroblast cells. Detected in the cytoplasm and neuropil of the hippocampus.
Protein: GLNE_ECO7I
Sequence: MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQDSISAHPEWLTELESQPPQADEWQHYVAWLQEALSNVSDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILQQLSYLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLSAIAELHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQLTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVSEDCFTAERELVRASWQKWLVEE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: RAP1B_CHICK
Sequence: MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL
What is the function of this protein?
Probable GTP-binding protein that possesses GTPase activity.  May play a role in endothelial cell polarity and endothelial barrier function (By similarity).
What are the official names of this protein?
Ras-related protein Rap-1b.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol.
Protein: YL15_ADE41
Sequence: METVSHLRLAFNKPGRGGDGPTFPVGGWLRAGSLEDGAAALAMISSSSSLGGLSSSSSSRLSQLSISSSSETSSAWLSSQDSSSSSHCSCSFCCFWDRRSAMACLFPLGGMFLRAARSGGGG
What are the official names of this protein?
Uncharacterized 12.4 kDa protein in 33 kDa protein region.
Protein: DNAA_XYLFT
Sequence: MESWSRCLERLETEFPPEDVHTWLRPLQADQRGDSVILYAPNTFIIELVEERYLGRLRELLSYFSGIREVVLAIGSRPKTTELTVPVDTTGRLSQTVPFNGNLDTHYNFDNFVEGRSNQLARAAAWQAAQKPGDRTHNPLLLYGGTGLGKTHLMFAAGNVMRQVNPTYKVMYLRSEQFFSAMIRALQDKSMDQFKRQFHQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGKQQIILTCDRYPREVNGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGATIPDEVAFLIAKKMHSNVRDLEGALNTLVARANFTGRAVTIEFSQETLRDLLRAQQQTIGIPNIQKIVADYYGLQIKDLLSKRRTRSLARPRQLAMALAKELTEHSLPEIGDAFAGRDHTTVLHACRQIKLLMETETKLREDWDKLMRKFSE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLS_LISMO
Sequence: MGLLAYLLVILLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDPNVKKHRDLIYLLLVNDGAILTQDNEVELFVDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFQKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDVGYIGGFNIGDEYLGASKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTHKIDYKARYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKQMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCYA_PROM3
Sequence: MERVRGACQSPILILLAIVLPFPSTSGPAIHPLIESLAARIRQRRAQLPELSPFALDSVMESISGQLDGEELLISNELHRCRGLRKLHLEIARLGGGLQVLHCVFFPDPRFDLPIFGADIVASPAGISAAIVDLSPVGLTMPVALLHGLESLPIPAFQQVRELPAWGSIFSPFVQFIRPASSEEESWFVDLADGYLKALISSVIDATPDASDAASTIQRHKSQLSYCIQQKRNDKTRGVLEKAFNPQWADRYIEEILFEDPPPL
What is the function of this protein?
Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
What are the official names of this protein?
Phycocyanobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: GPDA_POLSJ
Sequence: MKIVVIGAGAWGTALAVNTAGAVEAAGSDAPRHQVTLWARDAALVKAMQAERANTRYLPGVALPGNLLLQGGGETSLAEAVSGQDLIILATPVSAARGLLQSLQQASVPVVWLSKGFEAPVAAVPHSAPSLASFGLMVHEIRAQVATDLRAGILSGPSFALEVARGQPTALVAASEHAEVRDALVAAFHGTSLRIYASDDIVGVEVGGAVKNVLAIATGLCDGLQLGLNARAALITRGLAEMTRLGVTLGARAETFTGLSGLGDLVLTATGDLSRNRKVGLQLAQGKTLAEAVKSLGHVAEGVYCARTVVQRAAGLGVDMPIAQSVVALLDGKLRPAEAVAALMGRGPTTELA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMA1_PLAFG
Sequence: MRKLYCVLLLSAFEFTYMINFGRGQNYWEHPYQKSGVYHPINEHREHPKEYEYPLHQEHTYQQEDSGEDENTLQHAYPIDHEGAEPAPQEQNLFSSIEIVERSNYMGNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLKPVATGNQDLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNGPRYCNKDQSKRNSMFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQYEQHLTDYEKIKEGFKNKNASMIKSAFLPTGAFKADRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVEHNFPCSLYKDEIKKEIERESKRIKLNDNDDEGNKKIIAPRIFISDDKDSLKCPCDPEMVSNSTCRFFVCKCVERRAEVTSNNEVVVKEEYKDEYADIPEHKPTYDNMKIIIASSAAVAVLATILMVYLYKRKGNAEKYDKMDQPQHYGKSTSRNDEMLDPEASFWGEEKRASHTTPVLMEKPYY
What is the function of this protein?
Involved in parasite invasion of erythrocytes.
What are the official names of this protein?
Apical membrane antigen 1, Merozoite surface antigen.
What is the protein family that this protein belongs to?
Belongs to the apicomplexan parasites AMA1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MAK32_YEAST
Sequence: MMNEEDSTETKSLVITNGMFIIDDIERSKYNIHYKNVPGGGGTFAILGACIISSGNVTSKGLKWIVDRGSDFPKEVIREIDSWGTDVRFRDDFSRLTTKGLNYYEGSDDLRKFKFLTPKKQINVDDWISTFGQKIIDEMHAFHLLCSGSRCLDIINDLLRVKSSKGTKPIVIWEPFPDLCDFDHQNDIKSVMQRNDVTVILSPNAEESSRLFGLSSKEPTSLEECLALAHRFDDFMDENNMCILRCGALGSISVSEKFKNGRTYDHFPAYHFKTQSKVLDPTGGGNSFLGGFAVSYALTKSLDIASICGNIAAGAIIEQFGIPRYDPIAKTWNGITFLDRLKFYLSQSGLQYNINDLYKSLTR
What is the function of this protein?
Necessary for the structural stability of L-A double-stranded RNA-containing particles.  Necessary for growth at 37 degrees Celsius as well as for maintenance of the killer plasmid.
What are the official names of this protein?
Protein MAK32, Maintenance of killer protein 32.
What is the protein family that this protein belongs to?
To S.pombe SpAC4G8.14c.
Protein: PURL_ANASK
Sequence: MTEPITPEIVAQHGLKPDEYQRILEHLGRTPTLTELGVFSVMWSEHCSYKSSRVHLKTFPTSGPRVLQGPGENAGVVDLGDGLAAAFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPIASLNALRFGDPSHPRTAYLLEGVVAGIGGYGNCMGVPTVGGEVAFHPSYNGNCLVNAFTLGILPADKIFRGTAAGVGNPVMYVGAKTGRDGIHGATMASAEFDASTEEKRPTVQVGDPFMEKLLLEACLELFQTDAVVGIQDMGAAGLTSSSVEMAGRGGNGLDLFLDQVPLREEGMTPYEILLSESQERMLLVAAEGKEELVRSICEKWDLDVAVIGRVTASGRWRAHWRGAVVADLPVDPLTEGAPKYHRPMTPHPALPALHAFDLATLPEPADLGAALVRLLARPTIASKEWVYRQYDHMVRLVGAVRPGGDAAVVRLAVSHDAHAHKGIALSVGVNGRFCFLDPYLGAMHAVAECARNIACVGGEPIAITDCLNFGNPEKPEIMWQFAECVRGIGDACRAFGTPVVSGNVSLYNETEGQGILPTPTVGMVGLVEPVERTCHSTFRDAGDVIALVGSLQGEVGGSEYLSAEHGKEAGRPPALDLAREKAVQETVRRAVRAGLLSSAHDCSEGGLAVALAESCMMHEVPSDGSKPAWIGCAVRIPFPVRKDFVLFGEDASRILVSLPKENAARFVDLAQQCGAPVIRLGAVGGDRLEIQGALSVPVEELARAWRDGIPAVLRRDAAHAGATAPV
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_SALEP
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ISK8_MOUSE
Sequence: MKVIFSVAVLVLASSVWTSLAVDFILPMNFHMTGELLQKTKALCIKNIQLCWILSYFKVSEPICGSNQVTYEGECHLCSGILYEDRTVIKVHDGPCEHSSDESEH
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 8.
What are the subcellular locations of this protein?
Secreted.
Protein: RS19_AZOSB
Sequence: MARSIKKGPFIDAHLLKKVDAARASNDKRPIKTWSRRSTVLPDFVGLTIAVHNGRQHIPVYVSENMVGHKLGEFALTRTFKGHAASKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y546_STAHJ
Sequence: MSSMQETIINAFNFRHATKEFDPEKKVSESDFHTILETGRLSPSSLGLEPWRFVVIENEDLKEKLKPYSWGAQKQLNTASRFVIILARKNVTADSEYVQHIIRGIKKYEESTIPAVEDKFNNFQTNFHINDNERTLLDWASKQTYIALANMMTSAALLGIDSCPMEGFDLDKVTEILAEENVVDTEHFAPSVMVAFGYRKEEPKDKVRQPAEDVIEWI
What are the official names of this protein?
Putative NAD(P)H nitroreductase SH0546.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: GLPG_SALPK
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRVELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVVVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVASWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OLF19_MOUSE
Sequence: MELKNDTQISKFILLGISEDPLWQPFLFGLFLFMYLVTLLGNLLIIIATITDSHLHTPMYFFLSNLSFADICFTSASIPKMLVNIQTKNKVITYEGCISQVFFFILFGVLDNFLLAVMAYDRYVAICHPLHYMVIMNCRLCGFLVLGSWVTTALNSLLQSSMALRLSFCTDLKIPHFVCELNQLVLLACNDTFPNDMVMYFAAILLGGGPLAGILYSYSKIVSSIRAISSSQGKYKAFSTCASHLSVVSLFYSTLLGVYLSSSFTQNSHSTARASVMYSVVTPMLNPFIYSLRNKDLMGALRRLLRRKS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 19, Odorant receptor M12, Olfactory receptor 140-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BEX2_BOVIN
Sequence: MMPKEEQVLKNLTMENANEENEKKDEKEQDANKGEPLALSLGAGEYCVPRGNRRRFRVRQPILHYRWDMTQRLGKPQARMREENIERIGEEMRQLMEKLREKQLSHSLRAVSTDPPHHEHNDEFCLMP
What is the function of this protein?
Regulator of mitochondrial apoptosis and G1 cell cycle.  Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity (By similarity).
What are the official names of this protein?
Protein BEX2, Brain-expressed X-linked protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the BEX family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LPXD_NEIM0
Sequence: MIPATYTLSQITAQLGGEWRGEDISVTAVRPLADAQAEHISFLANPKYKAEVHDSSAGAVIVSAKAADGFEGRNLIVADDPYLYFAKVARLFSPVVKARGGIHPTAVVEPSATVPASCEIGANAYIGANTVLGEGCRILANAVVQHDCKLGDEVVLHPNAVVYYGCTLGRRVEIHSGAVIGADGFGLAFAGDSWFKIPQTGAVTLGDDVEIGSNTNIDRGAMSDTTVGNGTKIDNQVQIGHNCKIGSHTVIAAKTGISGSVTIGSYCIIGGGVGTVGHIEIADKTTIGGGTSVTHSITESGKHLAGIFPMSTHKEWARNAVYIHRLSEMNKRLKTLEQQLSDAGQDSK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: AMIF_PSESM
Sequence: MASGLGGLNKSPNGVVIGLAQLALPDPHTREALWAQTQKVVGMVAKARRSNPGMDLIVFPEYSLHGLSMSTAPEIMCSLDGPEVVALREACKEHRIWGCFSIMEANPQGNPFNSSLIVDDLGEIRLYYRKLHPWVPVEPWEPGDLGIPVCDGPRGSTLALIICHDGMFPEMARECAYKGADIMLRTAGYTAPIRHSWKITNQSNAFTNLMQTASVCMCGSDGTFDSMGEAMFVDFDGTIMAEGGGRADEIVCCELRPDLVREARVHWGVENNIYQFGHRGYVAVKGGARDCPYTYMRDLTAGQYRLPWENDVVHTDGRSCGFATPEREFKPTPSSWKE
What is the function of this protein?
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.
What are the official names of this protein?
Formamidase, Formamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: MTLD_BACVZ
Sequence: MIALHFGAGNIGRGFIGALLHHSGYDVVFADVNETMVSLLNEKKEYTVELADGGRQTEIIGPVSAINSAVQEQKLYRLINEAAIITTAVGPNVLRLIAPSIAEGLKRRTSSEPLNIIACENMIGGSSFLKKAVFGHLTEAERELVNRTVGFPDSAVDRIVPIQHHEDPLKVSVEPFFEWVIDRTGFAGGQPVLKGALFTDDLTPFIERKLFTVNTGHAVTAYVGYQRGLKTVKEAIGHPEIRRVVYDALSETGEYLVKAYGFKQSEHEQYMKKIIGRFENEYITDDVTRVARSPLRKLGANDRLVGPAKKIKEPNALAEGIAAALRFDYQDDPEAVELQKLIAEKGTSRVLQDICGIQLHEPLHGIVLKKLNQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: Y1568_LACP7
Sequence: MRIIISPAKKMVENIEALPVCGEPSFIDQTNQLLTYLKSLSYEEAKEIWNCNDQLATMNFERIASMNLKTKLTPAILSYQGIQYQYMAPEVLEKDQLEYIQEHLYILSGFYGILKPLDGVTAYRLEMQAKVNLSDKKDLYEFWGSLLYNKLREETDFILNLASKEYSKCIERYVTEDVRLVTCVFGERKGEKVIEKGTYAKMARGEMVRYMAEHKISTMSEVKKFDRLDFSYDENLSNETKLVFLKGESNVRDRK
What are the official names of this protein?
UPF0246 protein Cphy_1568.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: VSP_CROVV
Sequence: VIGGDECNINEHRFLVALYDPDGFLSGGIL
What is the function of this protein?
Snake venom serine protease that catalyzes the hydrolysis of arginine esters, kallikrein substrates Pro-Phe-Arg-MCA and Z-Phe-Arg-MCA.  Cleaves kininogen analogs to release bradykinin.  Induces contraction of the isolated rat uterus directly at high concentrations, but provokes more forceful contractions when injected in presence of bovine plasma.  Shows capillary permeability-increasing activity and hypotensive activity on the anesthetized rat.
What are the official names of this protein?
Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFA_LEPBP
Sequence: MSLSQEIVSLVKEAETVLSSATTEQELDALKNQFLGKKGKLTSVLKGLASLTVEEKKTVGKEANEAQTKLEQFVEAKRTILKESFYENQLGKESFDTLRPLPKKERGSLHPISQIQYEIEDIFTSMGFSVMDGPEVETDENNFGALNFTEDHPARDMQDTFYTVDGNLLRTHTSAIQVRALRKLKPPFRIIAPGRVFRYEEVDASHENTFYQVEGMVVGENISVAHLIYTMETLLSRVFRKEIKTRLRPGYFPFVEPGFELDINCLVCSGDGCSVCKQSGWLELLPCGLVHPNVLEAAGLDSKKWTGFAFGLGLDRLVMMRYGIHDIRYFQSGNLRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_ACIBY
Sequence: MAKVEQNEGLVEKLVAVDRVAKVVKGGRIFSFTALTVVGDGNGRVGFGRGKAREVPAAISKALEAARRNMITVDLAGTTLQHPVNARHGASRVYMQPASEGTGVIAGGAMRAVLEAAGVHNVLAKCYGSTNAANVVNATFKGLRDMTSPEKVAAKRGKSVEEIQG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: GSA_XANCP
Sequence: MNHSRSHALFSQAQNLMPGGVNSPVRAFKSVGGEPFFVARADGAYLFDVDGNRYIDYVGSWGPMIAGHNHPAVREAVERAIRDGLSFGAPCEAEVTMAETITRLVPSCEMVRMVNSGTEATLSAIRLARGATGRNRIVKFEGCYHGHGDSFLVKAGSGMLTLGVPTSPGVPAGLSELTATLSFNDFEGATALFDEIGAEVAAVIIEPVVGNANCIPPQAGYLQHLRTLCTRHGALLIFDEVMTGFRVALGGAQAHYGVTPDLTTFGKIIGGGMPVGAYGGGRDLMEQISPAGPIYQAGTLSGNPVAMAAGLAMLQLVQEPGFHARLSETTSLLCEGLEDAARAAGVAVTTNQVGGMFGLFFTDQIVENYAQATACDVTTFNRFFHAMLQQGVYLAPSAYEAGFVSSAHDEAVIEATLAAAREAFADVMR
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDA_MOOTA
Sequence: MTATGKREWTPDQLAAIRARRANILVAAAAGAGKTAVLVERIIQRLTDPEDPVSLENLLVVTFTEAAAAEMRQRIGAALEAAVARDPENEALRRQLLLLNRAHISTIHSFCLWVLRTYFYRLDLDPGFRVMDPAEVDLMQLEVMDRVLEEAFAAEPDGGPVTDLADSLGGRGDANLVDLVLRVWEFSRSLPWPEAWLEQVTSSYKVTPETPLESLPWYGELRQMITLELQEAAWYLEQARQAAAAPGGPAVYLDNLENEKEQVTRLLEEVGDLPWEELNAKLAAVHFGRLKAARGEDVDPVLKERAGKLRNQARDLLYALKEDLCRDEAAVRAELERSGELVATLVGLVRRFDAALREAKGRRNLIDFSDLEHLCLRVLLDEGAGPGRLQPSDVALELRQRFAEVLVDEYQDINTVQDAILALVSRQDVAENNLFMVGDVKQSIYRFRLANPDLFLAKYRQYPEGEGGPNRRILLKANFRSRQGVVDGVNFIFRQVFSPLVGELEYDAAAALVGRAGYPENPAAATPAVEVYLQEGKVAAGTGAGGRTDLPEAVGAGKGGKISGGAGYGETLSGYGAASPGGETGAPDLEDLTALEREALLVARRIRRMVRGTPERPGPEFQVWDQEKKEYRDLTYRDIVILLRATRDRAPVFLEALKQYGIPAYADLGSGYFAATEIETILSLLRVIDNPHQDIPLAAVLRSPIVGLSAGDLARIRLAAPGEDFFTAVVKAAGAPLLPFTARESAAPSSTATGSGGALDNQPGQDPVCIAPYIEDTQEPWRDDHPGPGAAAGKAVPGKDRDLASLLREFLARLERWRTLARRQPLGDVIWQLYRETGYLEFVGGLPGGAQRQANLRALLDRARQFEGFARHGLFRFLRFIERLQQNEGDLGTARALGENEDVVRVMSIHRAKGLEFPVVIVAGLGKGFNLRDLSGDFLLHGRLGLVPLYLDAAAGIKYPTLPYLATGHRLRLEALSEELRILYVALTRAREKLILAGTVRDLPRQAENWCASLFLPGEQLPPVLTSRAGNPLDWLLPALARHPDAAAIRDLAGVGGGHLLPDPSSWQVEVVRGGELPDRGSEEPGVQVRVTAGYQGTESAGQQENPGLLCSGWPGGSRELAGAVTPVQETAGKTVAPPGSNIAEAGVEPGVSPPAGAVSPQDETGPTWLQQEVARRLAWTYPRQPLTALPVKLTVTDLKRRFDVFNEGETPLRPGENTFTRRPAFLQSHQGLTAAERGTATHLVLQHVDLSRPVTGESLAGLLQEMVEREILTPEQAAAVDIRAIVTFFAAPLGKRLLARWEQVKRELPFSLAVPAVELYPGLPAEAAAGEIILVQGIIDCLVEEEDGFLLLDFKTGRIPPDPLAAYREQVRFYTRAVETIFNRNVKEVHLYFLDGGVDFKVTS
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.