PharMolix/UniProtQA huggingface dataset:
Protein: TRAF6_RAT
Sequence: MSLLNCENSCASSQSSSDCCAAMANSCSAAMKDDSVSGCVSTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACITKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLTVKCPNKGCVQKMELRHLEDHQVHCEFALVICPQCQRFFQKCQINKHIIEDCPRRQVSCVNCAVPMPYEEKEIHDQSCPLANIICEYCGTILIREQMPNHYDLDCPTAPVPCTFSVFGCHEKMQRNHLARHLQENTQLHMRLLAQAVHNVNLSLRPCDASSPSRGCRPEDPNYEETVKQLEGRLVRQDHQIRELTAKMETQSMHVSELKRTIRSLEDKVAEMEAQQCNGIYIWKIGNFGMHLKSQEEERPVVIHSPGFYTGRPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAVIRQNHEEVMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQGTFIKDDTLLVRCEVSTRFDMGGLRKEGFQPRSTDAGV
What is the function of this protein?
E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2.  Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation.  Leads to the activation of NF-kappa-B and JUN (By similarity).  Seems to also play a role in dendritic cells (DCs) maturation and/or activation (By similarity).  Represses c-Myb-mediated transactivation, in B-lymphocytes.  Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor (By similarity).  Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation.  Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production (By similarity).  Participates also in the TCR signaling by ubiquitinating LAT (By similarity).
What are the official names of this protein?
TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, RING-type E3 ubiquitin transferase TRAF6.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Nucleus. Lipid droplet. Note=RSAD2/viperin recruits it to the lipid droplet.
Protein: DUSC_YERPE
Sequence: MRVILAPMEGVLDSLVRELLSEVNDYDLCITEFLRVVDQLLPAKSFYRLCPELHNQSRTQSGTLVRIQLLGQYPEWLAENAARAVALGSYGVDLNCGCPSKLVNGSGGGATLLKDPELIYQGAKAMRAAVPAHLPVTVKIRLGWDSGDRQFEIADAVQQAGATELAVHGRTKEDGYQAERINWQAIGEIRQRLTIPVIANGEIWDYQSAQECMKVTGCDAVMLGRGALNVPNLSRVVKYNEPRMPWLEVVKLLQKYVQLEKQGDTGLYHVARIKQWLGYLRKEYTEATDLFGEIRALKNSKDIALAIQRINR
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: MOAA_VIBVY
Sequence: MERCSVAQQFEDRFHRKFYYLRLSVTDVCNFKCTYCLPDGYQPSGQKNSSFLNLSEIRRVVKAFADCGTSKVRITGGEPSLRKDFTDIIHTVASTQGIKRVATTTNGYRMEKHIGEWKEAGLNQINVSVDSLDPRMFHQITGENKFHQVMSGIDRAFEVGFEQVKVNVVLMKDLNHNELPAFLHWIKHRPIQLRFIELMQTGEMDTLFQQHHVSGVAIRNHLIANGWLLKVKAANDGPAQVFVHPDYQGEIGLIMPYEKDFCASCNRLRVSAKGKLHLCLFGDRGVELRDLMQQDDQEPDLIARIQSELQTKSVSHFLNEGQTGMTPHLASIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: URE2_BORPE
Sequence: MIPGEILTEPGQIELNVGRPTLTIAVVNEDDRPIQVGSHYHFAEANNALVFDRELATGYRLNIPAGNAVRFEPGMRRTVELVAVGGERRIFGFQGKVMGALK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_PSEPW
Sequence: MSACQTPLIVALDFPTRDAALKLADQLDPALCRVKVGKELFTSSASGIVESLCAKGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMSACREVLAKRSGPQPLLIGVTVLTSMEREDLAGIGLDIEPQEQVLRLAALAEKAGMDGLVCSALEAPALKAAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAQALAAVVAEIRS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: NLTP2_SORBI
Sequence: MARSMKLAVAIAVVAAAAAVVLAATTSEAAVTCGQVSSAIGPCLSYARGQGSGPSAGCCSGVRSLNSAARTTADRRAACNCLKNAARGIRGLNVGKAASIPSKCGVSIPYTISTSTDCSRVS
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 2, LTP 2.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: DGGGP_METVS
Sequence: MDLKAYFELIRLKNCLTAGFGALISGLIASNFTFGALFPLILAFLVVFFICGFGNSLNDIYDLKIDRINKPFRPIPSKRISLTDAKVFSYSIMIFGLIISLFNIYCFLMAVLNAVVLQKYAKIYKKNKIIGNMLVAYLTGSVFIFGGIAVGNVNVSLYLFSCAMFSMWAREIIKDYEDIEGDLKEKVSSLPIKYGEKSIYISLGLLLIAIGLSFLPYLTGIFGIYYLLMILICNLMFLAGFFNLLNAPSKKQARKTSKNIKLITNFVLIAFIIGSIFK
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP).  This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Digeranylgeranylglyceryl phosphate synthase, DGGGP synthase, DGGGPS, (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, Geranylgeranylglycerol-phosphate geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CPIN1_RAT
Sequence: MAEFGISPGQLVAVFCDKSSSEEALKKLVGRVQGLTGSEGQVFVENITQLLQSAHKESSFDVILSGIVPGSTSLHSPEALADMARILRPGGCLFLKEPVETTGVNNDKIKTASKLCSALTLSGLVEIKELQREALSPEEAQSMQEHLGYHSDSLLSVHVTGKKPNFEVGSSSQLKLLHKKSSSVKPVVDPATAKLWTLSANDMEDDSMDLIDSDELLDPEDLKKPDPASLKAPSCGEGKKRKACKNCTCGLAEELEKEQSKAQSSQPKSACGNCYLGDAFRCANCPYLGMPAFKPGEQVLLSSSNLQDA
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2.  Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1.  NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.  Has anti-apoptotic effects in the cell.  Involved in negative control of cell death upon cytokine withdrawal.  Promotes development of hematopoietic cells.
What are the official names of this protein?
Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: PLSX_LACGA
Sequence: MKKIAIDAMGGENAPKAIIDAVLKAKPKLKDIEFILFGDAEKINQLIPNEQKERIEVVATSEVIVDSDEPVRAIRRKKDSSMVVAANYVKAGKADALFSLGNTGALLACGIFIIGRIKGVERPALMPTLPSAKSEQGFNIIDVGANAQSKPEYLVQWAQMANFYAQKVRNIQNPTVALLNNGAEDDKGDPLHQEAYKLLKETKLNFIGNVEGNDLMEGKADVIVTDGFTGNATLKAIEGTASVILRLLKDSLLNNGLRPKVGALLAKPGLTALKKRFDTARYGGAVLLGVNAPVVKTHGRSNIRPIYYTLLQIDKMLSQDLVGEYKKYFSESR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: FABZ_CLOB6
Sequence: MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDVLRLSIELTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHP_CERS4
Sequence: MTRFLILSAVLAGPALAGDTSPAQLIAGYEAAAGAPADAERGRALFLSTQTGGKPDTPSCTTCHGADVTRAGQTRTGKEIAPLAPSATPDRFTDSARVEKWLGRNCNSVIGRDCTPGEKADLLAWLAAQ
What is the function of this protein?
High-spin cytochrome.  Transiently bind oxygen during autoxidation, which occurs with a half-life of 3 min with a 4-fold excess of O(2).  Also binds carbon monoxide, azide and cyanide.
What are the official names of this protein?
Cytochrome c-type protein SHP, Oxygen-binding heme protein, Sphaeroides heme protein.
Protein: Y1254_IGNH4
Sequence: MTTVKLTYFGHSAFHVEVDGVGIAIDPWITNPLSKTTLEDYLKNFKTDLVVITHAHEDHIGDALEIMRRTGAKFFSIHEIYVDLTQKGFQGIGANIGGPAKLDDVAPGLGIALTPATHSSYDKGVPTGAIIFKDGKALVYHAGDTGLFAEMQFIGELYAPKVALLPIGGHYTMDIEQALLATKLLRPEVVVPMHYNTFPPIRADPNEFKQKVESAGLAKVRVMEPGETVTFEF
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Igni_1254.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: RNFA_PECAS
Sequence: MTEYALLFVSILLVNNFVLVKFLGLCPFMGVSKKLETAIGMGMATTFVMTLGSMFSWLINEFILVPLDILYLRTMAFILVLAVVVQFSEMFVRKVSPELYRLLGIFLPLITTNCAVLGVVLLNINLSHGFLQSTIYGFGGAAGFSLVMVLFAAIRERLAVSDIPAPFRGSSIALITAGLMSLAFMGFTGLVKF
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FAL1_SCLS1
Sequence: MAEGIDRKMDDRMEFTTSADVTVAPTFQDMHLKENLLRGIYAYGYESPSAVQSRAIVQICKGRDTIAQAQSGTGKTATFSISMLQVIDTAVRETQALVLSPTRELATQIQSVVMALGDYMNVQCHACIGGTNVGEDIRKLDYGQHIVSGTPGRVADMIRRRNLRTRHIKMLVLDEADELLNRGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRILVKRDELTLEGLKQYFIAVEKEEWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGEMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPVNRENYIHRIGRSGRFGRKGVAINFVTSEDVRILRDIELYYSTQIDEMPMNVADLLT
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase fal1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS13_KLEP3
Sequence: MARIAGINIPDHKHTVIALTAIFGIGKTRSKAICAETGIAENVKISELSEEQIDILREAVGKFVVEGDLRREITLSIKRLMDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PVK1_HOSCA
Sequence: GSTGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, HosCa-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NOL3_RAT
Sequence: MGNMQERPSETIDRERKRLVETLQADSGLLLDALVARGVLTGPEYEALDALPDAERRVRRLLLLVQSKGEAACQELLRCAQQTVSMPDPAWDWQHVGPGYRDRSYDPPCPGHWTPEAPSSGTTCPGLPRASEEEEIGGPEDSEAVQPRTPEEPELEAEATKGDEPDLEQEMEPEPEPEVEPEPEPEPEPEPEPEPEPEPEPEPEREPDFQEGDESEGCENT
What is the function of this protein?
Apoptosis repressor that blocks multiple modes of cell death.  Inhibits extrinsic apoptotic pathways through two different ways.  Firstly by interacting with FAS and FADD upon FAS activation blocking death-inducing signaling complex (DISC) assembly (PubMed:15383280).  Secondly by interacting with CASP8 in a mitochondria localization- and phosphorylation-dependent manner, limiting the amount of soluble CASP8 available for DISC-mediated activation (PubMed:12191471).  Inhibits intrinsic apoptotic pathway in response to a wide range of stresses, through its interaction with BAX resulting in BAX inactivation, preventing mitochondrial dysfunction and release of pro-apoptotic factors (PubMed:15383280).  Inhibits calcium-mediated cell death by functioning as a cytosolic calcium buffer, dissociating its interaction with CASP8 and maintaining calcium homeostasis (PubMed:23382383).  Negatively regulates oxidative stress-induced apoptosis by phosphorylation-dependent suppression of the mitochondria-mediated intrinsic pathway, by blocking CASP2 activation and BAX translocation (PubMed:16639714).  Negatively regulates hypoxia-induced apoptosis in part by inhibiting the release of cytochrome c from mitochondria in a caspase-independent manner (PubMed:10590251).  Also inhibits TNF-induced necrosis by preventing TNF-signaling pathway through TNFRSF1A interaction abrogating the recruitment of RIPK1 to complex I (By similarity).  Finally through its role as apoptosis repressor, promotes vascular remodeling through inhibition of apoptosis and stimulation of proliferation, in response to hypoxia (By similarity).  Inhibits too myoblast differentiation through caspase inhibition (PubMed:17292893).
What are the official names of this protein?
Nucleolar protein 3, Apoptosis repressor with CARD.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Sarcoplasmic reticulum. Membrane; Lipid-anchor. Note=Phosphorylation at Thr-149 results in translocation to mitochondria (PubMed:12191471). Colocalized with mitochondria in response to oxidative stress (PubMed:16639714).
Protein: SYGA_MOOTA
Sequence: MNFQELIMTLQRFWAEQNCVIQQPYDLEKGAGTMNPATFLRVLGPEPWRVAYVEPSRRPTDGRYGENPNRLQHYYQYQVILKPSPDNVQDLYLQSLEAMGINPLEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEITQFTYFQQCGGFDCHPVSAEITYGLERLAMYIQQVNSVYDIEWVDGITYGDIHHQTEVDYSHYNFTFADTAMLFNLFNAYEAEAMRVVEQGLVQPAYDYTLKCSHTFNLLDARGAISVTERTAYIGRVRHLARLCAAAYLEQRQKLGYPLLKARQQQPEAPAPGPAAVVGGRDRKDACDVKEG
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NART_STAAT
Sequence: MYKTKGGFQLTLQTLSLVVGFMAWSIIAPLMPFIKQDVNVTEGQISIILAIPVILGSVLRVPFGYLTNIVGAKWVFFTSFIVLLFPIFFLSQAQTPGMLMASGFFLGVGGAIFSVGVTSVPKYFPKEKVGLANGIYGMGNIGTAVSSFLAPPIAGIIGWQTTVRSYLIIIALFALIMFIFGDTQERKIKVPLMAQMKTLSKNYKLYYLSYWYFITFGAFVAFGIFLPNYLVNHFGIDKVDAGIRSGVFIALATFLRPIGGILGDKFNAVKVLMIDFVVMIIGAIILGISDHIALFTVGCLTISICAGIGNGLIFKLVPSYFLNEAGSANGIVSMMGGLGGFFPPLVITYVANLTGSSHLAFIFLAVFGCIALFTMRHLYQKEYGSLKNG
What is the function of this protein?
Probably required for nitrate uptake under anoxic conditions.  Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate (By similarity).
What are the official names of this protein?
Probable nitrate transporter NarT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ANM8_MOUSE
Sequence: MGMKHSSRCLLLRRKMAENAVESTEVSSAPPQPPQPVIPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR
What is the function of this protein?
S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer.  Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.
What are the official names of this protein?
Protein arginine N-methyltransferase 8, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT8 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: EI24_CAEEL
Sequence: MVKFQIIARDFYHGFIDSFKGITFVRRIREEEAKEVKVEPPKPVERTVLMMRREKQGIFKRPPEPPKKKDSFLKKLWQIYAMNIGFLVLWQVCILILGLFFSFFDRTDLGHNIGYILIIPIFFASRIIQALWFSDISGACMRALKLPPPPVVPFSSMLAGTLISALHQIFFLIQGMLSQYLPIPLITPVIVYLHMALLNSMYCFDYFFDGYNLSFLRRKDIFESHWPYFLGFGTPLALACSISSNMFVNSVIFALLFPFFIITSYPANWNRKYEEEIPKIAFCRISYMFTELVGKFVKSITPTNNPTAARNNAQN
What is the function of this protein?
Involved in autophagy (PubMed:20550938, PubMed:24374177).  Thought to act in autophagasome and omegasome formation (PubMed:20550938).
What are the official names of this protein?
Ectopic P granules protein 4.
What is the protein family that this protein belongs to?
Belongs to the EI24 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Multi-pass membrane protein. Note=Forms a reticular pattern throughout the cytoplasm.
Protein: HTR7_HALSA
Sequence: MSGAAVFVDAVVAPLGDAVGAIGFGAAAALGYRNYRDTDAEAAFWMAFTFASLLGVTWTVSLMLEKAGVATQIFNLATGPLMATTVAVFAIGGTATLAIVEDMEALVEERAQRRQEAEEERAEAERAREKAEQKQAEAERQTAEAESAKQDARERSAEIEQLAADLESQATEVGATLEAASDGDLTARVDATTDNAEIAEVATVVNDMLTTMERTIDEIQGFSTNVTTASREATAGAKEIQDASQTVSESVQEIAAGTDDQREQLESVAEEMDSYSATVEEVAATAQSVADTAADTTDVATAGKQTAEDAIDAIDAVQETMQTTVANVDALEDLTTEIDDIAELISDIAEQTNMLALNANIEAARAGSGGGSNGDGFAVVADEVKELATESQRSAKDIAELIEEVQSQTATTVEEIRVAEQRVNDGAAAVEETVDAFGAVTENIQETTDGVQEISQAMDEQAQRSERVVSSVDDIATISQATADRAENVSAASEEQTASITEVTSSLQSLAAQADTLEDRLNEFRTEATGTAHGEATDAPAGQSD
What is the function of this protein?
Potentially involved in chemo- or phototactic signal transduction.
What are the official names of this protein?
Transducer protein Htr7, HTP V.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VF267_ASFB7
Sequence: MLLVLIDVDGFMGQLYNENGTQTILIPREVVIFYWEKNTASKILQLFFHGGIDPIFEKINQRSFSFQSRHIHHFTLDESPLPNSIALPTDTLQAFKAGKKMIFQHLVKITKDHEQILLLHKGGPEGEWVRSFNIPNATVQNLNDLCCPSVEKLVLKKRDYISSSIGCPKHIQGSNHCPVFECHVLFKWIQENTSIVQGVLKRPSLPYEEAVLFIEHRINMVDNHPFKKDSVKQNQKKKNWIATQFVQHGIYVDNGILSKIYNKYSLF
What is the function of this protein?
Plays a role in the inhibition of host RNA Pol-III-RIGI-mediated innate antiviral response.  Mechanistically, interacts with host E3 ubiquitin ligase RNF135, disrupting RNF135-RIGI interaction and impairing RNF135-mediated 'Lys-63'-polyubiquitination and activation of RIGI.
What are the official names of this protein?
Protein I267L, pI267L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I267L family.
Protein: RS10_NITHX
Sequence: MNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRSPHVDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PLCD_BOVIN
Sequence: MDLVALLKSHFLCHLIFCYVFIVSGLIINTIQLCTLLLWPVNKQLFRKINCRLSYCVSSQLVMLLEWWSGTECVIYTDPRAYPKYGKENAIVVLNHKFEIDFLCGWSLAERFGVLGGSKVLAKKELAYVPIIGWMWYFTEMVFCTRKWEQDRKTVSESLLHLRDYPEKYFFLIHCEGTRFTEKKHQISMQVAQAKGLPSLKHHLLPRTKGFAVTVRSLRNVVSAVYDCTLNFRNNENPTLLGVLNGKKYHADLYVRRIPLEEVPEEEDKCAAWLHKLYQEKDAFQEEYSRTGTFPETPVVPPRRPWTLVNWLFWASMLLYPFFRFVINMVSSGSSLTLASFVLVFFVASMGVRWMIGVTEIDKGSAYGNMDSKQKHSD
What is the function of this protein?
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity).  Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase delta, 1-acylglycerol-3-phosphate O-acyltransferase 4, 1-AGP acyltransferase 4, 1-AGPAT 4, Lysophosphatidic acid acyltransferase delta, LPAAT-delta.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EIF3K_DROME
Sequence: MSHLVKMENGQSQTIQEMLGCIERYNPDHLKTLESYVQDQAKNNTYDLEANLAVLKLYQFNPHMLNFDITYTILLKSLTSLPHTDFVMAKCLLLPQQMKDENVQTIIDLADILERADFTLFWQRAEVNRNMFRHITGFHDSIRKFVSHVVGTTFQTIRKDLLKELLGGIEDSTLESWIKRNGWKNQGQGLVIVAMQDDKIKTKNITEKIEFDNVGALMAQCL
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.