PharMolix/UniProtQA huggingface dataset:
Protein: Y596_HAES1
Sequence: MPKKVFQQEDVEQKITENFEPKQEFEQDELDIEMDCSQFETTMDRQNTDIPFQHMVRPKVTMWQKLLMATICLFSCGILAQSVQWLVDSWRDNQWIAFVFAMVSLFLVLLGLGAIIKEWRRLVQLKKRLILQEKSREIRSKSAVNLTEVSSEGKELCLKIASLMGIDDKSPQLIAWQEQVHEAYTEQEILRLFSQNVLIPFDRVAKKLISKNAVESALIVAVSPLAIVDMFFIAWRNIRLINQLAKLYGIELGYVSRLRLLRMVFVNMAFAGAADVIQDLGLEWLSQDITAKLSARVAQGIGVGILTARLGIKAMEFCRPIAVAPEEKLRLSHIQTELLGTLKTTLFSANKVKEKVR
What are the official names of this protein?
UPF0283 membrane protein HS_0596.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACYP2_DROME
Sequence: MAGSGVAKQIFALDFEIFGRVQGVFFRKHTSHEAKRLGVRGWCMNTRDGTVKGQLEAPMMNLMEMKHWLENNRIPNAKVSKAEFSQIQEIEDYTFTSFDIKH
What are the official names of this protein?
Acylphosphatase-2, Acylphosphate phosphohydrolase 2, AcPDro2.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: YEGS_SALG2
Sequence: MANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIPEALDKALKLAIAGNAMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALGGVSYLIHGLMRMDTLTPDRCEIRGENFHWQGDTLVIGIGNGRQAGGGQQLCPTALVNDGLLQLRIFTGEELLPALFSTLTQSDDNPNIIDDASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_MYCBT
Sequence: MANIKSQQKRNRTNERARLRNKAVKSSLRTAVRAFREAAHAGDKAKAAELLASTNRKLDKAASKGVIHKNQAANKKSALAQALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MATP2_SCHPO
Sequence: MKITAVIALLFSLAAASPIPVADPGVVSVSKSYADFLRVYQSWNTFANPDRPNLKKREFEAAPAKTYADFLRAYQSWNTFVNPDRPNLKKREFEAAPEKSYADFLRAYHSWNTFVNPDRPNLKKREFEAAPAKTYADFLRAYQSWNTFVNPDRPNLKKRTEEDEENEEEDEEYYRFLQFYIMTVPENSTITDVNITAKFES
What is the function of this protein?
In h- cells under nutritional starvation, P-factor induces alteration of cell morphology toward mating, arrest of the cell cycle at the G1 phase prior to the initiation of DNA synthesis and indirect transcriptional activation of the sxa2 gene which down-regulates the signaling pathway.
What are the official names of this protein?
Pro-P-factor.
What are the subcellular locations of this protein?
Secreted.
Protein: RL21_LAWIP
Sequence: MYAIIEAGGKQFCVEEGSKIFVSKIDAEVGTEIFFDKIFMIGGSSPQIGTPYINNAKVIAKVLEHGRDKKILVFKKWRRNDSRKLQGHRQDYTALKVTGIQL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: FTSH1_PHYMT
Sequence: MKTHYFKKIFNLKFLVIFFSILFCILLILDLTFERRIKGIKKRTDEIIKKIKDDNHLVEEIVFYETNSTIFEKSFYRVEILVKNKNNLTTKEKWYAVVDSIFFHEIHSLIKGRENIQIKDPKTDFHLSELILSLVPIVSSTIFMFYIISNIKKSSGKLNSNAKVSAKQKSLFTFKDVAGNTEEKEEMTELIDFLKQPQKYETIGAAIPKGVLLEGPPGTGKTLLAKALAGEASVPFYAVSGSEFVEMYVGVGASRVRTLFKEAKLNAPCVLFIDEIDVLGGKRGGNSSGGNQEKDQTLNQLLTEMDGFTQAKGIIVIGATNRADMLDAALLRPGRFDRKILVNLPDIKSRAEILKLHAQNKKLSSDIDFHQLAQQTPGMSGAQLAAVLNEASILTVRNHKDFITMTELSEALDRVLMGPAKKSIKYDPEERRMVAYHEAGHAVIGIKLKHAQKVQKITIIPRGNAGGYNLMMPEKETFFSSRKRMLAQIQSFLGGRVAEELVFDDISSGAFDDFRQATKIARLMVTKYGMSDLGVSQDSEFSDKKLIDTAIKKIIDNCYARTKHLMLENKTLLDQIAHLLLEQETITQAEIEQLVVNTKK
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: RSSA_FUSV7
Sequence: MAPSNLPSVFNATSQDIEMLLAAQCHLGSKNLQVHMENYLWKTRADGVNVLNVGKTWEKIVLAARIIAAIDNPADVCVISARPYGQRAVLKFASHTGATAIAGRFTPGSFTNYITRSFKEPRLIVVTDPRTDAQAIKEASYVNIPVIALTDTDSPTEYVDVAIPTNNKGRHAIGCVWWMLAREVLRLRGTIYSRETPWDVMVDLYFYRDPEAEAEEKVEEEKVPGAEEEGPAAIESGFAATGGDWEAPAAGFAGATGTGWDGAAGDEWGAAPATTEWAASAAPAAASGEAAKETTW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRI_VIBVY
Sequence: MNKETKLQVEAIKNGTVIDHIPAQVGIKVLKLFDMHNSSQRVTIGLNLPSSALGNKDLLKIENVFINEEQASKLALYAPHATVNQIEDYQVVKKLALELPEFVSDVFECPNSNCITHNEPVASNFRVFEKKGDVRLKCKYCEKVFSREIVTER
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: CUAOZ_ARATH
Sequence: MASASKKTSACPHHGGSLPPPKLVSAAPDTVAVWSDADDQRASKVSLESVIRPVDSFPDNTAKKPANKGISVMPRTETKHPLDPLSAAEISVAVATVRAAGANPEVRDGMRFIEVASVEPDKQVVALADAYFFPPFQPSLLPRTKSGPVIPMKLPPRRARLVVYNQKSNETSVWIVALSEVHAVTRGGHHRGRVVSSQVIPDVQPPMDAAEYAECEAIVKDFPPFIEAMKRRGIEDMDLVMVDPWCVGYHSEADAPSRRLAKPLIYCRTDSDSPMENGYARPVEGIYVLVDMQNMVVIEFEDRKFVPLPPPDPLRNYTPGESRGGVDRSDVKPLQIIQPEGPSFRVRGYFVEWQKWNFRIGFTPREGLVIHSVAYVDGSRGRRPVAHRLSFVEMVVPYGDPNEPHYRKNAFDAGEDGLGKNAHSLKKGCDCLGSIKYFDAHFTNFTGGVETIENCVCLHEEDHGILWKHQDWRTGLAEVRRSRRLTVSFLCTVANYEYGFYWHFYQDGKIEAEVKLTGILSLGALQPGETRKYGTTIAPGLYAPVHQHFFIARMDMSVDCKPAEAFNQVVEVNVRVDERGENNVHNNAFYAEEKLLKSEAVAMRDCDPLSARHWIVRNTRTVNRTGQLTGYKLVPGSNCLPLARPEAKFLRRAAFLKHNLWVTRYAPDEKFPGGEFPNQNPRAGEGLATWVKQNRSLEESDVVLWYVFGITHVPRLEDWPVMPVEHIGFTLMPHGFFNCSPAVDVPPNPCELETKESEVKEVVAPKALQTGLLSKL
What is the function of this protein?
Involved in putrescine catabolism in peroxisomes (PubMed:24287136).  Copper amine oxidase that can use putrescine and spermidine as substrates (PubMed:23915037).
What are the official names of this protein?
Amine oxidase [copper-containing] zeta, peroxisomal, AtCuAO1, AtCuAO3, AtCuAOzeta, Copper amine oxidase 3.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: APT_SYNPW
Sequence: MDLRQYVRDIPDFPKPGILFRDITPLLRDPAGWHEVIQRLVAVCDRWQPDLIVGIESRGFIVGTALATQLGKGFVPVRKPGKLPGEVIGIDYTLEYGSDRLEIHADALSDHPKVLLVDDLLATGGTASASAELVTKAGGELVGCGFVIELADLAGRAKLPEGVPVESLIIYG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT222_ASPNC
Sequence: MAFASPPASPPDEDGQARAPRYPGEDTTPTSRQEIWGWYAYGIAAEVFAVCGVGSFLPLTLEQLARERGFLQSSHLPCVGPDSPSAPKESSPAMFRRDDTNEQCVVGLMGLEINTASFAMYTFSLAVLVQALTLISFSALADYENNRKTLLVTFGFIGSATSMLFVFIAPPVFVLGALLVVVGVVCLGSSFVVLNSFLPVLVASDPSIQNSNKESAAELHRLDPEAEYVHARTSFDGDEPTHRPPTGLGLGGATGTSSPELQLSTKISSKGVGLGYCAAVFVQILSILLLFTLSKTSISKASGTLPLRFVLLLVGIWWFSFTMVSRRWLRNRPGPPLESTSTGASSHQPRWRIWLHLVAFAWKSLWKTVKIALKLREVIVFLVAWFLLSDAMATVSGTAILFARTELKMSTTMVALLSITATLSGMAGAFLWPIVSRYFGLKSNHTIMVCIALFELIPLYGMLAYIPLFKKWGVIGLQQPWEIYPLAIVHGVVSGGLSSYCRSFFGLLIPPGMEAAFYALYAATDKGSSFIGPAIVGVLIDATGQVRSGFFFIAVLIVLPIPLVWMVDAEKGRKEGLKISEDVVRGGEGEDEEVEGLLAR
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22-2.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: NUOK_RICFE
Sequence: MSRILNMNEYISLNHYLILSSLVFTIGMFGLFMHRKNIINILMSIELMLLAVNINFVAFSIYMQELSGQIFSIIILTVAAAETSIGLAILLIYFRNKGSIEITDINQMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COXX_CAUSK
Sequence: MARSTVLTPEDEATPAVRHARWQDYFQLMKPRVMSLVVFTALTGLLAARTPIHPLLGAVAVLCIAIGAGASGALNMWYDADIDAKMRRTRGRPVPMGLVKGEEAATLGVVLSLLSVMLMGMAINWLAAGLLAFTIVFYAVVYTMWLKRWTAQNIVIGGLAGALPPAIGWAAATGHAPLNAWLMVLIIFLWTPPHFWALSLYISTDYAKAGVPMLPVVKGAKETRKQILLYSLALIPVCLAPAFTGLGGWLYLAVSGLGGLVFLTLAVRVFRSLAGEASDPRPADRDLYEVGEAAAKRGKPVGDAKHARNLFAFSILYLFALFAALLAEAVLGLPILNLHVLELPL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APC11_MOUSE
Sequence: MKVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLNAQQVQQHCPMCRQEWKFKE
What is the function of this protein?
Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 11, APC11, Cyclosome subunit 11.
What is the protein family that this protein belongs to?
Belongs to the RING-box family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BMT6_YEAST
Sequence: MLLMRRFAFLTSSVYFKYIPIYSQYHYSSQFPINMNPKKVAQLPVHNKSTLPPQEIIDLFKITFLEELYPKDQDNEKSPLTEQIQAVKSDLYNRDYNAAFNNDSKRIAYCCRWSPSRATSYASVFAHFPELLKIIRCEIDDKDSNVLCIGGGAGGELVALASIFTLSRDFSSKFASALKIDNEVNKKPRNLNIQLVDIADWSTVVEKLTATIKSKWLYGDSEAESFNVNFTHKDCLQMTEPQDIKIYQGLDLITLLFTTNELFTQKKVESIKFLQRLNENCAPGCHLLILESAGSYSHITINNKKFPIQFLIDTILVGNRKDKGTTGPWSLVSENDSIWYRMDPKLDYSIPLENMRFFYRLYVKN
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(3) position of uridine 2843 (m3U2843) in 25S rRNA.
What are the official names of this protein?
25S rRNA (uridine(2843)-N(3))-methyltransferase, Base methyltransferase of 25S RNA 6.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes predominantly to the cytoplasm, with minor localizations in the nucleus (PubMed:24335083). Associates with pre-60S ribosomal particles (PubMed:24335083).
Protein: RSP5_EMENI
Sequence: MGSNLPAQPNLRVTIIAADGLYKRDVFRLPDPFAVATVGGEQTHTTSVIKKTLNPYWNEMFDLRVNEDSILAIQIFDQKKFKKKDQGFLGVINVRIGDVIDLQMGGDEMLTRDLKKSNDNLVVHGKLIINLSTNLSTPNPNQANGLHRTQLGASTSSGLVPQVAPTPSVPQAGPSSVDQSAAASSASLNPQRVPSATRPTSQIAPPNGAPPIANGQGVPRPNLSSFEDNQGRLPAGWERREDNLGRTYYVDHNTRTTTWNRPSANYNEQTQRTQREANMQLERRAHQNRMLPEDRTGASSPNLSETQPQAQTPPAGGSGASNSNVVSMMATGATTAGTGELPPGWEQRTTPEGRPYFVDHNTRTTTWVDPRRQQYIRMYGQNASGGNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQGVPQYKRDFRRKLIYFRSQPALRIMSGQCHVKVRRNNIFEDSYAEIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLENDIEGIIDLTFTVDDEKFGERRTIELKPGGEDIPVTNENKHEYVELVTEWKIVKRVEEQFNAFMSGFNELIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQEQDEVIQNFWKIVRTWDAEQKSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKSGDPIALPKSHTCFNRLDLPPYKSHEVLEHKLSIAVEETLGFGQE
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Probably involved in the regulatory network controlling carbon source utilization.  Ubiquitinates 'Lys-528' of the uric acid/xanthine transporter uapA at the cell membrane, leading to its internalization, sorting into the endosomal pathway to the vacuolar lumen where it is eventually degraded.
What are the official names of this protein?
E3 ubiquitin-protein ligase RSP5, HECT ubiquitin ligase A, HECT-type E3 ubiquitin transferase RSP5.
What is the protein family that this protein belongs to?
Belongs to the RSP5/NEDD4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P4KA1_ARATH
Sequence: MEALTELCDIIAKNPKQFSEKLAWICGRCPQTEWLLAESPRVSRSHLNAVLAVARIISKNPESIDNRAKSVVNEFLSAIPASFRRSFWPHSFPSQLISSFYCDFLSYLSCAADLSPEFGTEVARFTGEVVIAAIAPSSGDSDGDPAISKAFLVALSQHFPSILQSDGDKLITMLLDQFVLNRAPASPKEQRQQNSANSETDTSSSQGSPISTNRYPSGKTEMASPGDEVASHGSNLSSKSSSSVVMNGGSIVWKSGVDQLSFGFSEGSGGANPVFRQQVASFEDESIESLEKQEIAFRLITHILDKVKIDSKLQDQVRFIAKRQLQSMSAFLKSRKRDWNEQGQVLKTRVNAKLSVYQAAAKMKIKSLVSLETDGKTSKRLVLETLALLLDAADACLTSVWRKMKACEELFDSLLSGIAKIAVARGGQPLRVLLIRLKPLVLAVCALPDQGAMLESIFKTSCVIIESAWAKDRAPVDNFIMGLASSIRERNDYEEQVDREKQVPAVQLNVIRLLADLNVAVKKPEVADMILPLFIESLEEGDASTPSFLRLQLLDAVSRIATLGFDKSYRETVVLMTRSYLSKLSSVGSVESKTSAPEATTERVETLPAGFLTIASGLMDTKLRSDYRHRLLSLCSDVGLAAESKSGGSGVDFLGPLLPAVAEICSDFDPTMDVEPSLLKLFRNLWFYIALFGLAPPIVKTPTPPLKSTSNSVNSVGSMSATALQAVGGPYMWDNQWALAVQRIAQGTPPLVVSSVKWLEDELELNALHNPGSRRGNGNEKVASTQRLALSTALGGRVDVAAMNTISGVKATYLLAVAFLEIIRFISNGGILNGESSVSASRSAFSCVFEYLKTPNLTPAVSQCLTAIVHRAFETAVSWLEDRISLTGKDARNRELTTYAHACFLIKSMSQRDEHVRDISVNLLTQLRDKFPQVLWHSSCLDSLLFSVHDNTPSTVVNDPAWTAAVRSLYQKVVREWIIISLSYAPCTSQGLLQDKLCKANTWQRAQTTTDVVSLLSEIKIGTGKNELWSGIRTANIPAVMAAAAAASGANLKVSEAFNLEVLGTGVVSATVKCNHAGEIAGMRRLYNSIGGFQSGSTPSGFGGGLQRLISGAFSQAPQPEDDSFNEMLIARFVRLLQQFVNTAEKGGEVEKSQFRETCSQATALLLSNLGGESKTNVEGFSQLLRLLCWCPAYISTPDAMETGIFIWTWLVSAAPQLVSLVLAELVDAWIWTIDTKRGLFASDVRYSGPAAKLRPHLSPGEPEDPPESDPVDQIVAHRLWLGFLIDRFEVVRHNSAEQLLLLGRMLQRSTDLEWCFTRHPAAAGTFFSLMLLGLKFCSCQTQGNMQKFRSGLQLLEDRIYRTSLGWFAHQPEWYDVNIPNFCHSEALSVSVFVHFLSNELSESSQSDSKGKPRESGNLIDVTDQYHPVWGEMDNYTLGKEKRKQLLLMLCQHEADRLDVWAQPISSKDSPYSRLKISSEKWTEYAKTAFSVDPRIALSVASRFPANASVKSEVTQLVQTNIVDLRTIPEALPYFVTPKNVEENSVLLQQLPHWAACSITQALEFLTPAYKGHPRVMAYVLRVLESYPPERVTFFMPQLVQSLRYDDGRLVEGYLLRATQRSDIFAHILIWHLQGEDVQETPKDGSIDKNAAFQEILPQVRQHIIDGFSPNALDMFTREFDFFDKVTSISGVLFPLPKEERRAGIRRELEKIEMQGDDLYLPTAPNKLVRGIRVDSGIPLQSAAKVPIMITFNVIDRDGDHSDVKPQACIFKVGDDCRQDVLALQVISLLRDIFQAAGLNLYLFPYGVLPTGAERGIIEVVPNTRSRSQMGETTDGGLYEIFQQDYGPVGSTTFETARENFLISSAGYAVASLLLQPKDRHNGNLLFDDVGRLVHIDFGFILETSPGGNMRFESAHFKLSHEMTQLLDPSGVMKSKTWHQFVSLCVKGYLAARRQMDGIISTVQMMLESGLPCFSRGDPIGNLRKRFHPEMSEREAAHFMIHVCTDAYNKWTTAGYDLIQYLQQGIEK
What is the function of this protein?
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (Probable).  Can bind to phosphatidylinositol 4-monophosphate (PI-4-P or PtdIns4P), phosphatidylinositol 4,5-bisphosphate (PI-4,5-P2 or PtdIns4,5P2), and phosphatidic acid (PtdOH), but not to 3-phosphoinositides (PubMed:9712908).  May function upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway (PubMed:22318862).
What are the official names of this protein?
Phosphatidylinositol 4-kinase alpha 1, PI4-kinase alpha 1ao, PtdIns-4-kinase alpha 1, Phosphatidylinositol 4-OH kinase alpha1, AtPI4Kalpha1, PI-4Kalpha1.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region.
Protein: TRMB_DEIRA
Sequence: MIFRLGDFRFPDDPARLYPDTPDRPWVLEIGFGDGRFWPHYARTFPEPPNYLGVEISGVSLLKAHRRLKDAGLTNAVLTKLPAEVLVAQVIPHGSLDAIIVNFPDPWPKAGHEDHRLLRVPFFQVAASRLKPGGAALLTTDHDEYFEFACAQAEASGVMRVERVGPPPAALETKYAQKWRDLGLGVNHARFVPTRHDPVPNGTFAPYSEEDPAVPHAVLTLPADFSPQHFDKLTVRGKTWTVVLLDLYATLRRGGWVALAHVVEGDLTQEVLVGITEREDGTHLVRLAKFGGPIITPGVKAAVGAVTEWLEGQGAVVKHRGY
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TRPC_SYNY3
Sequence: MEIRRRPPNPPIKVDILQYQIKHPEAAPRHILEEIVWHKEKEVAQRRELVPLVKLQSLVKDMTPPLDFVGALRQSPRQPALIAEVKKASPSKGIIRADFDPVAIAKAYEAGGANCLSVLTDEKFFQGSFENLQLVRSAVQLPLLCKEFIIYPYQIYLARSRGADAVLLIAAILSDKDLRYFLKIIEGLGMAALVEVHTLEEMDRVLALDGVQLIGVNNRNLQTFTVDLQTTEDLFAQRREQLTQGDITLVSESGIYELADLQRLQQAGARAVLVGESLVKQPDPQQAIAALYGEV
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: UPP_LACCB
Sequence: MGKFTVLNHPLIQHKLTLIRDKHAGTKEFREIANEIAELMVYEITRDLPLESIEIETPMGKTIQKQLAGKKLAVVPILRAGLGMVDGVLRLIPAAKVGHIGMYRDEKTLKPHEYFVKMPPDIEQRDLIIVDPMLATGGSANMAIEALKKRGATSMRLVVLVAAPEGVKAVQAANPDVDIYAAALDDHLNENGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SYL_BORT9
Sequence: MSEYNFTKIEKKWQNYWDKHKTYKVNEDPNIPKEKRIYILDMFPYPSANGLHVGHPEGYTATDILTRYKLLNGFNVLHPMGFDSFGLPAENYAIQTGEHPKKITEKNIEKFKEQIKALGFAYDWDREIRTHDENYYKWTQWIFLKLYKKGLAYIKEMPVWYCPDLGTVLSNEEVIQTPDGPRSERGFHKVQRKPLRQWVLKITEYAERLIKDLEEIDWPESVKEMQKNWIGKSIGAEIEFSIKASKEKIKVFTTRPDTIFGVTYLVLAPEHNIVDKITKDELKTIIAEYKDKEILKSDLERTSLEKDKTGVFTGAYAINPITEEEIPIWIGSYVLGIYGTGAVMSVPAHDERDFEFAKKYNLPIKQVVSQTGNNEILTKPFTENGISINTPEEFNNLKTEKVKTKVIEWLTKNKKGQKKVNYKLRDWIFSRQRYWGEPIPIIIDDDLNEIPLEEDELPLRLPEIENYKPSDTGESPLSKVQNWVNVKRNGKIYKRETNTMPQWAGSCWYYIRYLDPNNEKEFASKEKINYWMPVDLYIGGAEHSVLHLLYARFWHKVLYDLGYVNTKEPFKKLINQGMITSFAYQDENGILIPNDEVKKRDNKFFSKTNNKELKQIIAKMSKSLKNIINPDDIIKEYGADSMRIYEMFMGPLTDSKPWNTQGLIGIFRFLNKIWAIKNKELTKESAAKEIISGLHKTIKKVTEDIENLNFNTAISSLMIFINELLKHDKNYLEIFKPLTIILAPFAPHLGEELWEYMGEQPSIFKNAKWPKYDPNLIIDNTREIVLQVNGKIKDKIILNKGINEDTLKDIALKNHKIMQNIQNKQIIKIITVKDKLINIVTK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_CLOBM
Sequence: MNNILVINGPNLNLLGKREPDIYGNITLENINQKIKLHFKNEDLRIDFFQSNEEGKIIDRIIESEKKYNAIVINPAAYSHYSIAILDAMRSINIPVVEVHLSNIYKREEYRKKSVTAEASLGVISGFGYYGYIMAIEFILNNLSIGK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: MSHC_ARTS2
Sequence: MKSWISRPVPQLPGRMPAVRIFDTAVGAYSTLDATGEQSLYVCGITPYDATHMGHAASYVAFDLLNRAWRDGGQRVAYVQNVTDVDDPLLERATATGVDWRDLAASQIELFQTDMAALNVLAPDHYVGAVESIPEIVPAIERLLHLGLAYRVTGTPGEPDGDVYYDVEAASKHSAEAKDAWTLGSVSGLSETEMLELFAERGGDPGRRGKRQALDPLLWRVARDGEPSWAGGELGSGRPGWHIECTVIAQKYLPAPFTVQGGGSDLIFPHHEMGAGHAYSLTGVPLARHFAHAGMVGLDGEKMSKSKGNLVLVSKLRAAGEEPAAIRLAILAHHYRTDWSWTEAGFAQAKTRLAEWRDALTMAPGESAATLIAEMRSELANDLNAPGALAAVDRWAVAAKQQAGAGSPMDQALVSDAVNALLGVEL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: COAD_BACHK
Sequence: MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQTPLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_STRT1
Sequence: MLEFPLINDTSRKIIHIDMDAFFAQVEMRDDPSLKDKPVIIGNDPRKTGGRGVVSTCNYEARKYGVHSAMSSKEAYERCPNAVFISGNYSHYREVGMQIREIFKCYTDLVEPMSIDEAYLDVTTNKLGIKSAVKVAKLIQYDIWQELHLTCSAGVSYNKFIAKLASDFQKPAGLTVVLPEEAQDFLEKLPIEKFHGVGKKSVERLHDMDIYTGADLLKISEITLIDRFGRFGFDLFRKARGISNSPVKPNRVRKSIGSERTYGKLLYSEDDIKAELTKNAKQVAESAQKAKKVGRIIVIKVRYSDFSTLTKRMTLDKSTQDFDTIDRISHSIFDQLEENSSGVRLLGVTLTGLEDQEGRQLDLDDLA
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.