PharMolix/UniProtQA huggingface dataset:
Protein: RL23_GLOVI
Sequence: MSSGTKRALADIIRRPLITEKGTRLLEENKYLFEVTPGANKIQIAQAIEELFSVKVTKVNTFNPPARQRRVGKYLGTRSSYKRAIVTLQEGDSITLFPEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: EFG_METC4
Sequence: MPRTHAIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHEGAATMDWMEQEQERGITITSAATTCFWRDKRLNIIDTPGHVDFTIEVERSLRVLDGAVCVLDGNQGVEPQTETVWRQADKYDVPRVVFVNKMDKIGADFFKCVADIIGRVAGKPVCLQLPIGAESSFKGVIDLIKMKAIVWSGEALGANFSEEEIPADLADQAVEYRTKMIEACVELDDDAMTAYLDGVEPDEETLRKLVRKAVQLRAFHPVLCGSAFKNKGVQPLLDAVVDYLPSPADRGEIKGLDFKTEEEVVRHPTDSDPFSMLAFKIMDDPHVGTITFCRVYSGKVESGANVINSSRDKKERVGRMLLMHANNREDVKEAFAGDIVALAGLKDTRTGDTLCDPKDAVILEKMEFPEPVIEIAVEPKSKADQEKLGIALSKLAAEDPSFRVSTDQESGQTILRGMGELHLDIKVDILRRTYKVDANIGQPQVAYREKLTRRQEIDYTHKKQTGGTGQFARVKFVVEPNEPGAGFAFESKIVGGAVPKEYIPGVEKGLNSVLGAGVLAGFPVVDVKVELIDGAYHDVDSSALAFEIASRAAFREALQKGGSVLLEPVMKVEVVSPEEYTGSVIGDLNSRRGQIQGQDMRGNANVINAMVPLANMFGYVNQLRSFSQGRANFTMQFDHYEEVPRGEADKVIAKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_SALPC
Sequence: MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCM1A_XENLA
Sequence: MLEQVQKFLLSRAACEGSDSHTRYAELFHKLDVNKDGKVDILELQEGLKAMGMAVGKGAEEKIVEAGDTNKDGHLDFGEFMRYLEEHEKKMKIAFTSLDKNKDGKIESSEVMNSLKTLGINISLDHAEKILKSMDSDGTLTVDWNEWRDHFLFNPADNIQQIIRFWKHSTVLDIGDSLTIPDEFTEEEKKTGQWWKHLLAGGMAGAVSRTGTAPLDRLKVMMQVHGTKGNSNIITGLKQMVKEGGVRSLWRGNGVNVIKIAPETAMKFWAYEQYKKLFTSESGKLGTAERFIAGSLAGATAQTSIYPMEVLKTRLAVGKTGQYSGMFDCAKKIMQKEGILAFYKGYIPNILGIIPYAGIDLAIYETLKNYWLQNYAKDSANPGVLVLLGCGTVSSTCGQLASYPLALIRTRMQAQASIEGAPQLNMGGLFRKIVAKEGFFGLYTGIAPNFLKVLPAVSISYVVYEKMKIQLGI
What is the function of this protein?
Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane.  Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter.  By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways.
What are the official names of this protein?
Mitochondrial adenyl nucleotide antiporter SLC25A24-A, Small calcium-binding mitochondrial carrier protein 1-A, SCaMC-1-A, Solute carrier family 25 member 24-A.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AROK_BACLD
Sequence: MNAAIRDKNIVLIGFMGVGKTTIGQLVSKKLGRDFIDIDHEIEKDFQMTIPEMFQQKGEAFFRQTEKEYIFQMCEHTMGNIVSLGGGAFQQEEIRKKCLEHCFVIFLDLRWENWKQRMDLLIENRPVLHNRTIEEMKQLFNERKSIYAFHHLKVETDNRSAEETADYIVEMLKLGQS
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y012_METKA
Sequence: MLRVATAECFTHGFVGREIHASASGYTGELGSEILGTELEGKVSVVAACFIPTVSGLRSLLGIDPPEPDEVSKSGAKAYREETDRKVAVMMARAVRERTGADVGIGTTAGIGRGAICLDDGEITLLGRTDVHANLLKPDERIRKRQLQGIKRSLVMFRAYFRCELDELLEEEWVEEVTRDLP
What are the official names of this protein?
UPF0254 protein MK0012.
What is the protein family that this protein belongs to?
Belongs to the UPF0254 family.
Protein: HBA2_TACAC
Sequence: VLTDAERKEVTSLWGKASGHAEDYGAEALERLFLSFPTTKTYFSHMDLSKGSAHVRAHGKKVADALTTAVGHFNDMDGALSDLSDLHAHKLRVDPVNFKLLAHCFLVVLARHHPEEFTPSAHAAMDKFLSRVATVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-2, Alpha-2-globin, Hemoglobin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TYDP1_SCHPO
Sequence: MSTLEPEKRRQHEDKSNEIIDSPIFLNKISALPESENVHCLLLKQLIGSPQLKQTWQFNFCVDLNFLLENMHASVFPTVDVRITHGYDSKSDSLARLTAQMNHCPVNVKLYSVYVPMWGTHHSKIMVNFFKDDSCQIVIHTANLVEPDWIGMSQAIFKTPLLYPKANDSLSTSSVPEYGNPSKIRKHEGSLDIKDDRNCDIIDVDSAFENFKHKSDTRSSDDLGVIGRQFQQDFLAYLKNYRHTYELIEKLKMYDFSAIRAIFIGSVPGKFEGEEESSWGLGKLKKILKMLEKDSKKDEKTKFEESDICISQCSSMGSFGPKQEYIAELTDGFGCQRGNWKFLFPTVKEVQQSMLGWQSGSSIHFNILGKTAASQVETLKKGKNLCKWVAMKAGRQRVAPHIKTYMRFSNDGELLRWVLVTSANLSKPAWGTLEGHKAKSRSTRGLRIRSYEAGVLLYPKLFEESQRAPCIMTPTYKTNTPNLDEKRREFYGKRVIGVRMCWDFPPVEYEDKDEIWSPVINRTDKDWLGYVWPPNW
What is the function of this protein?
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate.  Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue.  Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals.  Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA.  May have low 3'exonuclease activity and may be able to remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups.  Has no exonuclease activity towards DNA or RNA with a 3'phosphate (By similarity).
What are the official names of this protein?
Probable tyrosyl-DNA phosphodiesterase, Tyr-DNA phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the tyrosyl-DNA phosphodiesterase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUTA_YERE8
Sequence: MKIGVFIPIGNNGWLISSNAPQYMPSFELNKAIVQQAEHYQFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIKIYATAATLTLPPAIVARMASTIDSISNGRFGLNVVTGWQKPEYEQMGLWPGDEYFSRRYDYLSEYVEVLQDFWGTGQSDFNGEFFQMDDCRVSPQPQTPIKLICAAQSDAGMAFSAKYADYNFCFGKGVNTPTAFAPTAARLQKAAEQAGREVSSYVLFMIIADETDELARAKWESYKAGADTEALAWLTEQSGKDTQSGADTNVRQMADPTSAVNINMGTLVGSYANVAKMMDDIATVPGTEGILLTFDDFLSGIENFGQHIQPLMNSRADIVDTLPPAAREVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: SLY1_DROME
Sequence: MLTLRERQINAIKQMLNLNSQQPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDLDRNDRFWMTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAILNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQLPESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVMECRSNAETDDYLYLDPKLLKGGEVLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFLKELSALGGEIQSPTATS
What is the function of this protein?
Non-vital for development.
What are the official names of this protein?
Protein sly1 homolog.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: IL5_HORSE
Sequence: MRMLLHLSVLALGAAYVCALAVESPMNRLVAETLTLLSTHRTLLIGDGNLMIPTPEHKNHQLCIEEVFQGIDTLKNQTVQGDAVAKLFQNLSLIKGYIDLQKKKCGGERWRVKQFLDYLQEFLGVINTEWTIEG
What is the function of this protein?
Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils.  Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity).  Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB.  Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity).
What are the official names of this protein?
Interleukin-5, IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF.
What is the protein family that this protein belongs to?
Belongs to the IL-5 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMT22_ORYSJ
Sequence: MHLRMASPPQPGPYMPDLPAVPAWLNKGDTAWQLVAATFVGIQSMPGLVVIYGSIVKKKWAVNSAFMALYAYASTLIVWVLVGFRMAFGDRLLPFWAKAGPALTQDFLVQRAVFPATAHYGSDGTLETPRTEPFYAEAALVLFEFEFAAITLVLLAGSLLGRMNIKAWMAFTPLWLLFSYTVGAFSLWGGGFLYQWGVIDYSGGYVIHLSSGVAGFTAAYWVGPRLKSDRERFSPNNILLMIAGGGLLWLGWAGFNGGAPYAPNVTATVAVLNTNVSAATSLLTWTCLDVIFFGKPSVIGAVQGMMTGLVCITPGAGLVHTWSAMLMGMFAGSVPWFTMMILHKKSTFLMKVDDTLAVFHTHAVAGILGGVLTGLLATPELCALDCPIPNMRGVFYGSGIGQLGKQLGGALFVTVWNLIVTSAILLCIGLFIPLRMSDDQLMIGDDAAHGEEAYALWGDGEKFDVTRPETTRTGGAGGAGREDTMEQRLTNMGARGVTIQL
What is the function of this protein?
Involved in ammonium transport.
What are the official names of this protein?
Ammonium transporter 2 member 2, OsAMT2;2.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ERPA_SALSV
Sequence: MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RNH_MOOTA
Sequence: MKEVTIYTDGACSGNPGPGGWGAVLIYGDKRKELSGAEPSTTNQRMEITAAIAALRVLKEPCRVHLYSDSAYLVNAFRQGWLARWERNGWLTVKKQPVENQDLWRELLQVASRHQVEWLKVKGHSDNPENNRCDELARAAIAALRRQEIPSS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_AJECG
Sequence: MSLLREAEKCLANQKTYASLNAFITPLQRAGPWRDRVRDSDTRRERGVTKSPLDGKLVAIKDNICTRDMPTTCASRILDTYTSPFNATVVESLEKSGAIIAGKTNLDEFGMGSHSMHSHFGPVKNVTESRREPISPGGSSGGSAVAVATGQCYAALGTDTGGSVRLPAAYTGTVGFKPSYGHVSRWGVVAYANSLDTVGVLGSSISTIREVYKTINHPDLHDPTNLPPATRTRLTAAVHNSSTTRSSPSPYLRIGIPTEYNIHELSPTVRTAWQRSIVHLQRMGHTILPVSLPATKHALAAYYVLAPAEASSNLARYDGVRYGTRDTDAPDDAEPGGYLYASSRGKGLGSEVKRRILLGAFSLSADAIDNYFLQAQRVRRLVQADFERVFRVKNPLLPAVDVDADVDGRDKKQIAGDNAGVDVLVVPTAPTLPPTVESLKRASTVETYMNDIFTVPASLAGLPALSVPVQMRGLSTVGDGDESKGDGADAAFGSVGIQAIGQFGDDEMVLHVGEMLEGMHG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: STB5L_HUMAN
Sequence: MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFLINEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGRKSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASAITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASEGVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDSFARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFSCMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKVFSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF
What is the function of this protein?
Plays a role in vesicle trafficking and exocytosis inhibition.  In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane.  Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (By similarity).  Promotes as well axonal outgrowth (PubMed:25504045).
What are the official names of this protein?
Syntaxin-binding protein 5-like, Lethal(2) giant larvae protein homolog 4, Tomosyn-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat L(2)GL family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein. Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane.
Protein: YIDD_ANAD2
Sequence: MIRAALVLLVRIYQRLVSPLLPPACRFYPSCSAYAVTALQRHGALRGSWLTVRRLCRCHPFHAGGVDPVPELTPKR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: STMP1_HUMAN
Sequence: MLQFLLGFTLGNVVGMYLAQNYDIPNLAKKLEEIKKDLDAKKKPPSA
What is the function of this protein?
Microprotein involved in mitochondrial respiratory chain complex III (ubiquinol-cytochrome c oxidoreductase) and complex IV (mitochondrial cytochrome c oxidase complex) assembly (PubMed:35450818).  Required for the formation of mitochondrial supercomplexes (SCs) (PubMed:35450818).  Also required for the activation of the NLRP3 inflammasome (By similarity).
What are the official names of this protein?
Short transmembrane mitochondrial protein 1.
What is the protein family that this protein belongs to?
Belongs to the STMP1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Mitochondrion intermembrane space.
Protein: Y151_ARCFU
Sequence: MRSLSMTIMFMHPSTPLQLLLHPPVLLLAYLSPRIPLLEDFEGGFLSRRFALPQNDVYNQKKNPEHRNYDEDEPQQPVHSPFLCILIHEIGQNQPRNPPY
What are the official names of this protein?
Uncharacterized protein AF_0151.
Protein: TORD_SHEB8
Sequence: MSQVDINHARALVYQLLSSLFAREVDEQRLKELTSEAAQQFWEQLSLEAKLTQSVDKIRSTLNGIKDDETLLELAADYCGLFLVGTKHSASPYASLYLSGEDEPLLFGQQHQQMSEFLHQSKLQVQSHFPEPADHLAVMLAYMAHLCCHSEDSVQLSFLQTCVDSWLAKFINQLTQCDKNGFYSAVAILTLAWVKQDIAQLEPAEAVIS
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1L_HALH5
Sequence: MKIANGQTVIQLFERWSPKSLAVEGDKNGVLIGTLNKPIQRVLTALDVTESVIDEAIELGAELILAHHPIIFRPLSSIRTDTAYGRIIEKAIKHDLTIYAAHTNLDITKGGVNDLMADALGLKDIEVLAPTTTESLYKLVVFVPHTHTDQVREALGRAGAGHIGNYSYCTFNSKGTGTFKPEEGTNPFIGKQGALEFVEELKIETIVTEGQKNKVVAAMIKSHPYEEPAYDLYPLANEGETLGLGRIGYLHESMTLEEFAKQVKKAFDVPTARVVGSLETQIRKVAVLGGDGNKYMAHALRKGADVIVTGDVYYHVPHDALMDGLNIVDPGHNVEKIMKQGVKEKLEKLLKDKKYDTEVVASSVHTDPFTFI
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: NADD_HELPJ
Sequence: MNTMNSVLECKELALYGGSFDPLHKAHLAIIEQTLELLPFVQLIVLPAYQNPFKKPCFLDAKTRFKELERALKGMPRVLLSDFEIKQERAVPTIESVLHFQKLYRPKTLYLVIGADCLRHLSSWTNAKELLKRVELVVFERIGYEEIQFKGRYHPLKGIDAPISSSAIRASLGV
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: GPMA_STRR6
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: 3SA1A_NAJAT
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCNKLPPIASKTCPAGKNLCYKMFMMSDLTIPVKRGCIDVCPKNSLLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 1a, Cardiotoxin-1a.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: TRMN6_SALPC
Sequence: MSQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVADVKRILDIGTGSGLLALMLAQRTDDNVPIDAVELDAGAAMQAQENVAHSPWPHRITVHTDDIQRWAPRQTVRFDLIISNPPYYEPGVECATPQREQARYTATLDHQTLLAIAADCITEDGFFCVVLPEQIGNAFTQQALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGSDQHYSESYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTP4_HUMAN
Sequence: MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAALWMEEGLPAQNAPGTL
What is the function of this protein?
Has a broad substrate specificity with the ability of cleaving all nucleotide di- and triphosphates with the exception of adenosine di- and triphosphate (ADP and ATP).  Preferentially hydrolyzes CTP, UDP, CDP, GTP and GDP.  Can use either Ca(2+) or Mg(2+) equally.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 4, NTPDase 4, Golgi UDPase, Lysosomal apyrase-like protein of 70 kDa, Uridine-diphosphatase, UDPase.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CADH_PINRA
Sequence: MGSLETEKTVTGYAARDSSGHLSPYTYNLRKKGPEDVIVKVIYCGICHSDLVQMRNEMGMSHYPMVPGHEVVGIVTEIGSEVKKFKVGEHVGVGCIVGSCRSCGNCNQSMEQYCSKRIWTYNDVNHDGTPTQGGFASSMVVDQMFVVRIPENLPLEQAAPLLCAGVTVFSPMKHFAMTEPGKKCGILGLGGVGHMGVKIAKAFGLHVTVISSSDKKKEEAMEVLGADAYLVSKDTEKMMEAAESLDYIMDTIPVAHPLEPYLALLKTNGKLVMLGVVPEPLHFVTPLLILGRRSIAGSFIGSMEETQETLDFCAEKKVSSMIEVVGLDYINTAMERLEKNDVRYRFVVDVAGSKLDN
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers.  Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase, CAD.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.