PharMolix/UniProtQA huggingface dataset:
Protein: CHEZ_HELPY
Sequence: MTQEELDALMNGGDLENLEALETKEETKEEAKEEAKEEAKEEAKEKEEIKEESSSQKMTVKKEDAEKYGKISPNEWPPPPPTEEHKVVHQLDDVTRDSEVKATQIFDQLDLIGASAEKIAKMVKKIQEPLQKHQEIFDNLHGHFPHVESFKTALNEQQEILNALKSIEEEAANCSDSSMQAMDIMQFQDIHRQKIERVVNVMRALSQYMNSLFEGKIDDSKRVSSATFITGDDDKDLASADDIEALIASFGAK
What is the function of this protein?
Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).  Dephosphorylates also CheV2 but not CheV1 or CheV3 (PubMed:20497335).  In addition, forms a distinct chemotaxis regulatory complex with ChePep independently of the core chemotaxis signaling proteins (PubMed:26061894).
What are the official names of this protein?
Protein phosphatase CheZ, Chemotaxis protein CheZ.
What is the protein family that this protein belongs to?
Belongs to the CheZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the cell poles.
Protein: COFG_GLOVI
Sequence: MRERTVTYSPAFTLVPTRECFNRCGYCNFRADRGAAWLQPAEVRALLLPLVGSGVVEILVLSGEVHPHDPRRGEWFAMIEDICAVALELGFLPHTNCGVLSFEEMRALQQLNVSLGLMLEIDSNRLLGGVHRHAPSKIPALRTAQLEWAGALGIPFTTGLLLGIGETPAEREDTLRTIARLQDRHGHIQEVILQPHSPGGSQSWAGEPLGDAQLLGVVRLARQILPAEITIQIPPNLVGDPVPLLEAGARDLGGIGPVDVVNPDYAHPVVERLGERLAAAGWRLEPRLPVYPHLDKRVATALQPLLGEHRARLCQAAVT
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: CYB_CEREO
Sequence: MINTRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFHPYYTIKDILGILLLVLFLMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALISSILILILMPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEYPFIIIGQLASILYFFIILVLMPITSTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYPM_RAT
Sequence: MEGLLTRCRTLSALATCSLRHSRCIVRKCYHCAPGRGQRLVVSRMFQPQNLREDQVLSLEGRASDLTCKSQRLMLQVGLILPASPGCYHLMPYTVRAVEKLVRVIDQEMQAIGGQKINMPSLSPAELWRATGRWDLMGRELLRLKDRHGKEYCLGPTHEEAVTALVASQKKLSYKQLPLLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSSEAAQETYSLVCDAYCRLFDRLGLRWMKARADVGSIGGTMSHEFQLPVDIGEDRLVVCPSCHFSANTEIVDLSQKICPDCQGPLTETKGIEVGHTFYLGTKYSSIFNAHFTNAHGESLLAEMGCYGLGVTRILAAAIEVLSTEDCIRWPSLLAPYQVCIIPPKKGSKEAAATEIVERLYDDVTEALPQLRGEVLLDDRTHLTIGNRLKDANKLGYPFVIIASKRALEDPAHFEVWSQNTGEVVFLTKEGVMELLTGVHVV
What are the official names of this protein?
Probable proline--tRNA ligase, mitochondrial, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYR_FRATW
Sequence: MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEEIVEHIDAEDIFAKLEVAKPGFINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFGGPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVVSDVHLGDWGTQMGMLIEEIKLQSPQLVYFDENYTGEYPTESPVTVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVALWQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDTNKDGVPPLIVIKKDGGVMYGTTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAERTKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLISQAKEYAKNRMPDENDDSIIDQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTVVRAKSILRKIFGDNYDIKSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVNCPINNLDDESLKKARIALCMATVKAMTIASDLIGISIPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUNA_BACPU
Sequence: MLIFETYLILFKTVQITKRRIERRRLRLLNQCFTKKEGVSNREMASYNYVEVLQKSMLFYEAQRSGRLPESNRLNWRGDSGLKDGKDVGHDLTGGWYDAGDHVKFGLPMAYSAAVLAWTVYEYREAYEEAELLDEILDQIKWATDYFLKAHTGPNEFWAQVGDGNADHAWWGPAEVMPMNRPAFKIDEHCPGTEVAAQTAAALAAGSIIFKETDASYAAKLLTHAKQLYAFADRYRGKYTDCVTNAQPFYNSWSGYVDELIWGGIWLYLATNEETYLNKALKAVEEWPQDWDYTFTMSWDNTFFASQILLARITKENRFIESTERNLDYWTTGLVQNGKVERITYTPGGLAWLDQWGSLRYAANAAFLAFVYADWVSDQEKKNRYQSFAIKQTHYMLGDNPLNRSYVVGFGQNSPKHPHHRTAHGSWSNQLTNPPSHRHTLYGALVGGPNAQDQYDDDISDYISNEVATDYNAAFTGNIAKMVQLFGEGQSKLPNFPPKEQVEDEFFVEAAVMHNDTTSTQVKAVLYNRSGWPARSSQTLSFRYYVNLSEVFAKGFTEKDIQVTAAYNEGASLSPLKVYDASSRVYFAEIDFTGVVISPRGESEHKKEIQFRLSAPNGSNIWDASNDYSYQGLTSNMQKTTKIPVFEDGVLVFGTLPDK
What is the function of this protein?
Active on carboxymethyl cellulose and carboxymethyl cellulose-RBB but not avicel, xanthan gum, carboxymethyl-curdulan-RBB or carboxymethyl-xylan-RBB.
What are the official names of this protein?
Endoglucanase A, Endo-1,4-beta-glucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: INO3_ARATH
Sequence: MFIESFKVESPNVKYTENEIHSVYDYQTTELVHENKNGAFQWTVKPKTVKYEFKTDTHVPKLGVMLVGWGGNNGSTLTAGVIANREGISWATKEKVQQANYFGSLTQASSIRVGSFNGEEIYAPFKSLLPMVNPEEIVFGGWDISDMNLADAMARAKVLDIDLQKQMRPFMEHMVPLPGIFDPDFIAANQGSRANHVIKGTKKQQLEQVIKDIREFKEKNKVDKVVVLWTANTERYSNVVVGLNDTTENLMSSLDKDEAEISPSTLYAIACVLENVPFINGSPQNTFVPGLIELAIKRNCLIGGDDFKSGQTKMKSVLVDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVGSNGILYEPGEHPDHVVVIKYVPCVGDSKRAMDEYTSEIFMGGKNTIVMHNTCEDSLLAAPIILDLVLLAELTTRIQFMSENEGKFHSFHPVATLLSYLSKAPLVPPGTPVVNALSKQRAMLENVLRACVGLAPENNMILEYK
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner.
What are the official names of this protein?
Probable inositol 3-phosphate synthase isozyme 3, AtIPS3, MIP synthase 3, Myo-inositol 1-phosphate synthase 3, AtMIPS 3, MI-1-P synthase 3.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_SHEB8
Sequence: MAKEDNIEMQGTILETLPNTMFRVELENGHVVIAHISGKMRKNYIRILTGDKVTVQLTPYDLTKGRIVFRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEA2_ECOLX
Sequence: MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPEVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSAAQERRKQKENKEKDAKDKLDKESKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPDLSKQFKGSNKTNIQKGKAPFARKKDQVGGRERFELHHDKPISQDGGVYDMNNIRVTTPKRHIDIHRGK
What is the function of this protein?
Colicins are polypeptide toxins produced by and active against E. coli and closely related bacteria.
What are the official names of this protein?
Colicin-E2.
What is the protein family that this protein belongs to?
Belongs to the colicin/pyosin nuclease family.
Protein: SYV_SALTO
Sequence: MPAKASLEGIEKVWSRVWEQNGTYRFDRSVTRSEVYSVDTPPPTVSGALHVGHVFSYTHSDAIARFQRMRGRAVFYPMGWDDNGLPTERRVQNYYGVRCDPSLPYDPGYTPPAEPPSRPQPISRRNFVELCRNLTELDEQAFEALWRHLGLSVDWSLTYATIDDRSRAISQRAFLRNLARGEAYLADAPTLWDVTFRTAVAQAELEDRERQGTYYRLAFHSATGDKIYVETTRPELLPACVALVAHPDDERYQHLLGSTAVSPLFGVPVPIRAHPLAQPDKGSGIAMICTFGDLTDVLWWRELALPTRPVMGRDGRLLPEPPPGIVNADAVAAYQTLAGLTAFSAKAKVVELLRAAGDLEIAPRPTTQTVKFYEKGDKPLEIITTRQWYVRNGGRDTELRSALVHRGRELTWSPEFMRSRYENWVEGLSGDWVISRQRFFGVPIPVWYPLDDSGEPDYAHPILPDDVALPVDPSSDAPTGYQESQRNQPGGFMADPDVMDTWATSSLTPEIAGGWTVDDDLFARVFPMDLRPQAHEIIRTWLFATVLRSHQEFNCLPWTTVLLSGWILDPDRKKMSKSKGNTVTPMALLEKYGSDAVRYWAVSGRPGTDTAFDTGQMKIGRRLAIKILNATTFVLRFGSPTLLAPHMAHVTEPLDRSMLARLASVVDSATTGFTQHDYTRSLECTEQFFWSFCDDYLELVKERAYGEPDDRAVRSAHAALALALHTLLRLFAPMLPFVTEEAWSWWQEGSVHRAAWPTGQELVGPDVSAEANRSTEASGSGEAGTDLLGLASDVLAAIRRAKSEAKQSMRAPVAQLTLRGRASDLAAFALVSRDVRAAGVVREVDTAEADTPLTPEITLG
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFA_ECOL5
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIVAGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRMA_BACFN
Sequence: MKYFEFTFDTHPCTETVNDVLAAVLGEAGFESFVEREGGLTAYIQQSLYNEETLKTELANFPVPDTEISYTFAEAEDKDWNEEWEKNFFQPIVIGDRCVIHSTFHQDVPKAEYDILINPQMAFGTGHHETTSLIIGELLDSELTGKSLLDMGCGTSILAILARMRGAKPCTAIDIDEWCVRNSIENIELNGVTDIAVSQGDASALQGKGPFDVVIANINRNILLNDMKQYVACMHPGSELFMSGFYIDDIPAIRREAEKHGLTFVHHQEKNRWAAVKFVL
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF12_THEVL
Sequence: EVIAQLTMIAMIGIAGPMIIFLLAVRRGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).  PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PAND_PSYWF
Sequence: MLLTLLKGKLHRARVTHADLHYEGSCGIDGDLLDLAGIRENESIDIYNVSNGKRFRTYAIRAEAGSGIISLNGAAAYMADLGDIVIICAYAQMDEQEADTHKPKLVYCNEDNTVKDTANIIPVQVS
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP1_CORGL
Sequence: MADQAKLGGKPSDDSNFAMIRDGVASYLNDSDPEETNEWMDSLDGLLQESSPERARYLMLRLLERASAKRVSLPPMTSTDYVNTIPTSMEPEFPGDEEMEKRYRRWIRWNAAIMVHRAQRPGIGVGGHISTYAGAAPLYEVGFNHFFRGKDHPGGGDQIFFQGHASPGMYARAFMEGRLSEDDLDGFRQEVSREQGGIPSYPHPHGMKDFWEFPTVSMGLGPMDAIYQARFNRYLENRGIKDTSDQHVWAFLGDGEMDEPESRGLIQQAALNNLDNLTFVVNCNLQRLDGPVRGNTKIIQELESFFRGAGWSVIKVVWGREWDELLEKDQDGALVEIMNNTSDGDYQTFKANDGAYVREHFFGRDPRTAKLVENMTDEEIWKLPRGGHDYRKVYAAYKRALETKDRPTVILAHTIKGYGLGHNFEGRNATHQMKKLTLDDLKLFRDKQGIPITDEQLEKDPYLPPYYHPGEDAPEIKYMKERRAALGGYLPERRENYDPIQVPPLDKLRSVRKGSGKQQIATTMATVRTFKELMRDKGLADRLVPIIPDEARTFGLDSWFPTLKIYNPHGQNYVPVDHDLMLSYREAPEGQILHEGINEAGSVASFIAAGTSYATHGKAMIPLYIFYSMFGFQRTGDSIWAAADQMARGFLLGATAGRTTLTGEGLQHMDGHSPVLASTNEGVETYDPSFAYEIAHLVHRGIDRMYGPGKGEDVIYYITIYNEPTPQPAEPEGLDVEGLHKGIYLYSRGEGTGHEANILASGVGMQWALKAASILEADYGVRANIYSATSWVNLARDGAARNKAQLRNPGADAGEAFVTTQLKQTSGPYVAVSDFSTDLPNQIREWVPGDYTVLGADGFGFSDTRPAARRFFNIDAESIVVAVLNSLAREGKIDVSVAAQAAEKFKLDDPTSVSVDPNAPEE
What is the function of this protein?
Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component, E1p, PDH E1 component.
Protein: TRPB_ROSDO
Sequence: MANDLFNSFMTGPDENGRFGDFGGRFVSETLMPLILELEEQYENAKTDESFWAEMNDLWTHYVGRPSPLYFAERLTDHLGGAKVYMKRDELNHTGAHKINNVLGQIILARRMGKTRIIAETGAGQHGVATATVCAKFGLKCVVYMGAHDVERQAPNVFRMRLLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQAIIGKEVRTQMTAAEGRFPDTVIAAIGGGSNAMGLFYPFLDDKEVGIIGVEAGGKGVNAKMEHCASLTGGRPGVLHGNRTYLLQDDDGQILEGFSISAGLDYPGIGPEHAWLHDIGRAQYVSITDVEALEAFQLCCELEGIIPALEPSHALAHVMKIAPDLPSDHIICMNMCGRGDKDIFTVAKALGFEMGEFA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PGAM2_MOUSE
Sequence: MTTHRLVMVRHGESLWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEFDICYTSVLKRAIRTLWTILDVTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYTSISKDRRYAGLKPEELPTCESLKDTIARALPFWNEEIAPKIKAGQRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELDQNLKPTKPMRFLGDEETVRKAMEAVAAQGKAK
What is the function of this protein?
Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction.  Can also catalyze the reaction of EC 5. 4. 2. 4 (synthase), but with a reduced activity.
What are the official names of this protein?
Phosphoglycerate mutase 2, BPG-dependent PGAM 2, Muscle-specific phosphoglycerate mutase, Phosphoglycerate mutase isozyme M, PGAM-M.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PANB_ALIB4
Sequence: MSIIKNNFEKMNITKIKNSKNNKKLTVITAYDALFAKLFEEIADMILVGDSLNMSFAGRPDTLSATLEQMIYHTNAVCNGAKNAFVIIDMPFGTYINKDEALKNCVEVYRQTNANAVKIEGGEDKADIIKHLTSNAVAVMGHIGLMPQYVRSEGGYKVRGKTKEDEEQLIRDAIAVEKAGAFSIVVEGVKSDVAKKITQAVNIPIIGIGAGVDTDGQVLVWSDMLGFFEEFKPKFVRHYLDGAELVKEAVNQYRNDVQDKSFPSKEEEY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCC1_STAAM
Sequence: MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
What are the official names of this protein?
Carbamate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RYK1_DROME
Sequence: MAPNLLTIGLLLTLIASGQAHLNIFLNLHEVLRLIGVSAELYYVREGAINDYALNFAVPVPANISDVTFTWQSLVDHPLPYSINIATSDTEVLPRPILNISRIGDVPVEPQTWGIALKCSGTRNAEVTVTINVEVILDRATNNNTNLIFKRKKICLREEQDSAHEEYDDDDLDLLQTARKGHGGDIHYVDRNDEHVVANGHQAPEKQRPVVTESPVGRGNSGGSKRDFDPMLRENLVPPASGLVTLIVGGILALVLVSTLILIAYCAKGPSKRHPSNGVHLIKTSSFQRLPTISSTAHNSIYVCPSTITPTYATLTRPFREYEHEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGRIYRGTYNDCQEVLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVLYAATGSVRNLKSFLQDPSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSEFHTQITRYV
What is the function of this protein?
Probable coreceptor of Wnt proteins.  Involved in neuronal pathway recognition and ventral muscle attachment site selection.  Non-vital for development.  May be part of a signal transduction cascade involved in learning and possibly memory.
What are the official names of this protein?
Tyrosine-protein kinase Drl, Protein derailed.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TMEDA_USTMA
Sequence: MIPPRSLGSTAALLLVLLFTTLASAIKFDLPSNAHPHTKCIWNYALSDSLVIVTASVVAKEPFDFSHQRVDIEVVDGSQHNNVYLSKKAIKGETRLAINTHSHADLGVCFKNTLTSKSGNQIPVVTIDLDVDIGADAVDYNAIANQESLSGLETEMRKLEAVANEIVNEMEYLKKRELRMADTNLSTNMRVTNFAILTLIALIALGVWQVFHLRGFFKRKYLID
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Endoplasmic reticulum vesicle protein 25.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: TGT_YERPP
Sequence: MKYELQKTDGRARRGRLVFERGVVETPAFMPVGTYGTVKGMTPEEVKETGAQILLGNTFHLWLRPGQEIMKLHGDLHDFMQWHGPILTDSGGFQVFSLGAMRKIKEEGVHFKNPINGDSVFLSPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAARSRQRFDELNNKNALFGIIQGGVYEDLRDVSVKGLVDIGFDGYAVGGLAVGEPKEDMHRILEHVCPQIPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKDDTATLDEHCDCYTCRHYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRQAIEEGKLEHFVEDFYGRIGKPVPPLNV
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: NCAP_I72A2
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVDGKWMRELVLYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRKTRGAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACNSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPAFSVQRNLPFDKSTIMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: QUEC_SHEB8
Sequence: MSTSLVSKPSASKAVVVFSGGQDSTTCLIQALTQYDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVMDVTLLNELAISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAEAIITGVCETDFSGYPDCRNDFVKAMESALVQGMDKQLKIITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGVIGDGCGDCPACHLRKRGLDDYLQDKTTVMASLDASEPNA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PLSY_CHRVO
Sequence: MTTTAFAFVLAAYLIGSLSFAVIVSKAMGMADPRSYGSGNPGATNVLRTGKKLAAALTLLGDGAKGWVAVALASWLGPRYGLGEQGIALCALAVLFGHMWPVFFGFKGGKGVATAVGILFGINPWLALAALATWLFMAFVVKISSLSAIVACVLAPVYAFFILGPHSVYFGTCIIIAIVVVHRHKSNLIKLMTGQEDKIGNKGDAG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.