PharMolix/UniProtQA huggingface dataset:
Protein: SYD_CLOTE
Sequence: MGEALKGLKRTIMCGQLREENINEQHTVMGWVQRKRNLGGLIFIDLRDRDGILQVVFGEEINKEAFEKADTVRSEYCLAVTGKIIKRQAVNENLPTGIVELQGESIKILSESETPPIYIKEDLDAAENIRLKYRYLDLRRPDMQKILKIRHKTAKAVRDFLDKEEFLEVETPMLTKSTPEGARDYLVPSRNYPGMFYALPQSPQLFKQLLMVSGFDKYFQIVKCFRDEDLRANRQPEFTQIDLEMSFVEMDDVIDLNERLIQYVFKNVVGKDIKLPIERMPYKIAMSKYGSDKPDLRFGMEIENLDDVLKETSFKVFKEVIDNGGTVSAIKAENCAGMGRKQIDKLGDFVKTFKAKGLAWIAYKEDEIKSPIAKFLTEEELKSIIDKMDAKVGDLILIVSDAKEKVVQQSLGQLRLHLAKELGLLKDNDELRFVWVTEFPLVSYNEEEDRWEAEHHPFTAPMDEDIQYLDTDPGKVRAKAYDIVLNGEELGGGSIRIHDTKLQEKMFEVLGFTEEKAWERFGFLLEAFKFGPPPHGGLAFGFDRMIMFLSGTENIKDVIAFPKNQNAFCPMTEAPNVVDEVQLDELGIKIKK
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y153_MYCTU
Sequence: MSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNPLIRDEFAKVLVSSAGTAWARLADADLAWLDGDQLGRRVHRVACDYQAVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQPSVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWLAEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGNTQRWNRMRERLGLDIDVQALTYHEPDRSDAAQWLATHGWQVHSVSNREEMARLGRAIPQDLVDETVRTTLLRGRLVTPAQPA
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0145.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: ASIP_TRAOB
Sequence: MDVTRLLLATLLVFLCFFTVYSHLPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKKSKQISRKEAEKKRSSKKEASMKKVAQPRTPLSAPCVATRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMM_STAES
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGVISTPGVAYLTKEMEAALGVMISASHNPVADNGIKFFGSDGFKLSDDQENEIEQLLDQTNPDLPRPVGEDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCNPDGYNINEQCGSTHPEKLAEAVLETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMYKNQELNGNMIVSTVMSNLGFYKALEKEGIQSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVLMDYNTTGDGLLTGVQLASVIKMSGKTLSELASQMKKYPQSLINVRVTDKYRVEENIHVQEIMTKVETEMNGEGRILVRPSGTEPLVRVMVEAATDADAERYAQSIADVVEDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL5_ECO8A
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PLPL_CRYNB
Sequence: MPPSPPSSAAADQWNIDYVNEDSPLSPRSFSLPPESPQLSTASPIHQRVSRKRQRATSQGLTYNVIRWPLLFFIFFIIYLEFSAYVITRQIVNVFEWLVAWRGYKAKLRKELRKAKTYDEWVNTAKKLDKHLGFDDWKDVEEDSYFDWALVRRVRRTLTRLRAANDTRGLMDALAVCVRANFAGTESVKMYSETFIGTKKAVEAHIKEVAACLDYVRTATDVSLEEKRAFFRAVNKHYGSSALCLSGGASFGYYHFGVIKAFLEADLLPRVITGTSAGGLCAALLCTRTDSELKELLVPELADKITACSDPFTVWFKRFRQTGARFDTIDWARRSMWFTRGSLTFKEAYTKTGRALNISVVPSDRHSPTILLNHLTAPNCLIWSAILASAAVPGILNPVVLMAKDRSGNIKPHNLGGSRFKDGSLREDIPLGSLHTQFNCNFSIVSQTNPHIHLFFFAPRGSVGRPVAHRKGKGWRGGFILSALESYIKLDLSKHFKVIRDLDLMPQILQSDWSGVFLQRFSGDLTLTPRSTIGDWFHILSDPDRPQMKRMLRVGERVAWPALGMVRNRMTVERAILRGRSEVRTALSHDRTSNDPATSLPETNPELTGALDHVPIESDVDAGFVSRSRRARNKTGSKGGDTPEEQLNLAGVFQLDESSKGVRRRKQKKSGMPLVAEPLGELPEVSPTHSPIATESPQRNYTSNFGDSFRHVRAPSLPALSSPFRSIRSNTSSSSNNVQSPSSSQRFRSQLSITRWFGGVSESSSDEEDEDLGGLQSGEATASSGEEGIPTFQLDSAVESHSDRSEDEMLHSGANVKEEYQSEESEGKIPIPGGERVTQEKIDASMASGERLRPAGGSKGSAKTPPVQDGA
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein CNBE2340.
What is the protein family that this protein belongs to?
Belongs to the PLPL family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: 3604L_ASFL5
Sequence: MNSLQVLTKKVLIETKAFSKYHEDDIFILQQLGLWWEIGPIGFCKQCKMVTGGSMSCSDVDSYELDRALVKAVKENQTDLIKIFVSWGAEINFGIMCAKTKQTKDLCIQLGADPEFLDVGLYNMFVYLIKQKKVLLAIDIYYDNISILDSFDSHDFHVLIDFVYNRFILYLDEKEEEMTRNTLVLKFWYKFAIDFKLTKPIRYLSKKFPHLDIWRLQTAIYLGNIDEVHHAYFQEDIRLSLNVMMFLACARPGNKLGIYYCFALGADLDRALERLISFNSINRKISGETRLCIEGSYLSNVYFCIGLGANPYTKKIQETIKQKHSNIMILLFSKKKILSPHSVLQNKILDPSDVRKMISTYENTESFYPFFSLAVKLIQQAK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-4L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: DYLT2_HUMAN
Sequence: MEKRGRGVKSSPIQTPNQTPQQAPVTPRKERRPSMFEKEAYTQILRERLRESIHNVQYVEPPFDDSIADIGKEWKSALAKLKFANSYRMEPLKKFQAHSVETKVQQILTESLKDVKYDDKVFSHLSLELADRILLAVKEFGYHRYKFIIKVLFIQKTGQAINIASRWIWDIAWDSWVAAKHEAESYVALVLVFALYYE
What is the function of this protein?
May be an accessory component of axonemal dynein and cytoplasmic dynein 1 (PubMed:11278908, PubMed:12584439).  Candidate for involvement in male sterility (By similarity).
What are the official names of this protein?
Dynein light chain Tctex-type protein 2, T-complex testis-specific protein 3, T-complex-associated testis-expressed protein 3, Tcte-3, Tctex1 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasmic granule. Membrane; Peripheral membrane protein. Note=Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis.
Protein: COBT_THET8
Sequence: MDPEVFAQARLRMDQLTKPPRALGYLEEVALRLAALQGRVKPELGRGAVVVAAADHGVVAEGVSAYPQEVTRQMVLNFLRGGAAINQFALAADCAVYVLDVGVVGELPDHPGLLKRKVRPGTANLAQGPAMTPEEAERALLAGREAARRAIAEGATLLAAGDMGIGNTTAAAALTAALLGLPPEAVVGRGTGVGEEGLRRKRQAVARALARLHPGMGPLEVAAEVGGLELVAIAGIYLEGYEAGLPLVLDGFPVTAGALLAWKMAPGLRDHLFAGHLSREPGHRHQLEALGLRPLLDLDLALGEGTGAVLAMPLLRAAARILHMATFQEAGVSRG
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RL24_METNO
Sequence: MAAKVKKGDTVVVLTGRDKGRSGEVIQVMPKENRALVRGVNLVKRHQRQTQAQEGGIISKEAAIDLSNLAVADPKDGKPTRVGFRILEDGRKVRFAKRSGDLIDG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: COBQ_PYRFU
Sequence: MGKALMIQGTMSGVGKSLIATALCRIFSDLGYDVVPFKSQNMSLNSAPSIEGGEISRAQYLQAIACRKKPSIKFNPILLKPEGNMRSQVVFLGEPIGSVSARDYMLSKKIELFRKSMEVLKSLMKRHDLVIIEGAGSPVEINLKDYDIANMRVAREVNAPVILVADIDRGGSFAQIVGTMELLSEEERNLVMGFVFNKFRGDPSLLYPGFKFLEKKYGKPVLGVVPYIDHRLPEEDSLAEFPRAKGEVHIQIIKLPHISNFTDFEPLHWANGVDYVTKAEEIKGDIIIIPGSKNTVEDLIWMRENGIEDAIIEAHREGSFIVGICGGFQMLGEKIIDNVESKRGEVKGIGLLPAKTIFAREKRTNHLKAEVLWEPARGMRVEGYEIRFGRSTTRRPFSVIKWVNGRRVEEFEGAVGERTFGTYLHGIFHNFEFTEAFLNLIRREKGLEPIKIREWSIEDEINRFAKIVRESIDVDYIIEFLGL
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Probable cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RS21_ECO57
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: B2J2_SICPE
Sequence: WIMGHMVNAIEQVDEFLDLGANAIEFDVDFDDDGVAKYTHHRIPCDCGRLCTKYAVFTEYLDYVRQVTTPGDPKFRKELVLHALDLKLQRISSEKAYAAGVDVATKLLDHYWMRGWNGGRAYILLNIPLVEDYEFIRAFKDTLRKEGHEQYNAKVGINFTGNEDLDEIREVLEKLGEDEHIWQADGITSCFPRGTERLKKALEKRDTPGYKYIPKVYAWTLVRSSIMRRSLRLGVDGVMSNYPDSVVKVLKEKEFSDKFRLATYADNPWEKFTPI
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SpeSicTox-betaIIA3ii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RNC_EHRRG
Sequence: MITNAISKIIKYDFKNTQLLNEALTHPSVLSKDNNNFNYERLEFLGDAVLNLVVSEMLFNIFPYDTEGNLAKKKTALVCGTKLVEIAQSINLGIFIIMSDGERSCGGANNSNNLENALEALIGAIYLDGGLKAAKDFIFLFWKNSATHMKVPPQDAKTILQEWAQSKGFPAPSYHIINKSGPDHNPCFTVEVRINSHETLHATGHNKKLAEQKAASLMLAKINYKIK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_MYCTU
Sequence: MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDGLVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRLAKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGRSAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQIMADTGLAYYSGDDALNLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLCNAMSRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASVLR
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQC_PSE14
Sequence: MSEATALSPAEFEQALRAKGAYYHIYHPYHVAMYEGRATREQIQGWVANRFYYQVNIPLKDAAILANCPDREIRREWIQRLLDHDGAPGEDGGIEAWLRLGQAVGLDPDQLRSQELVLPGVRFAVDAYVNFARRANWQEAASSSLTELFAPQIHQSRLDSWPQHYPWIDPAGYEYFRTRLGQARRDVEHGLAITLQHYTTYEGQQRMLEILQFKLDILWSMLDAMSMAYELNRPPYHSVTDQKVWHKGITL
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: RSH4A_HUMAN
Sequence: MEDSTSPKQEKENQEELGETRRPWEGKTAASPQYSEPESSEPLEAKQGPETGRQSRSSRPWSPQSRAKTPLGGPAGPETSSPAPVSPREPSSSPSPLAPARQDLAAPPQSDRTTSVIPEAGTPYPDPLEQSSDKRESTPHHTSQSEGNTFQQSQQPKPHLCGRRDVSYNNAKQKELRFDVFQEEDSNSDYDLQQPAPGGSEVAPSMLEITIQNAKAYLLKTSSNSGFNLYDHLSNMLTKILNERPENAVDIFENISQDVKMAHFSKKFDALQNENELLPTYEIAEKQKALFLQGHLEGVDQELEDEIAENALPNVMESAFYFEQAGVGLGTDETYRIFLALKQLTDTHPIQRCRFWGKILGLEMNYIVAEVEFREGEDEEEVEEEDVAEERDNGESEAHEDEEDELPKSFYKAPQAIPKEESRTGANKYVYFVCNEPGRPWVKLPPVIPAQIVIARKIKKFFTGRLDAPIISYPPFPGNESNYLRAQIARISAGTHVSPLGFYQFGEEEGEEEEEAEGGRNSFEENPDFEGIQVIDLVESLSNWVHHVQHILSQGRCNWFNSIQKNEEEEEEEDEEKDDSDYIEQEVGLPLLTPISEDLEIQNIPPWTTRLSSNLIPQYAIAVLQSNLWPGAYAFSNGKKFENFYIGWGHKYSPDNYTPPVPPPVYQEYPSGPEITEMDDPSVEEEQAFRAAQEAVLLAAENEESEEDEDEEDDYD
What is the function of this protein?
Component of the axonemal radial spoke head which plays an important role in ciliary motility (PubMed:19200523).  Essential for triplet radial spokes (RS1, RS2 and RS3) head assembly in the motile cilia (By similarity).
What are the official names of this protein?
Radial spoke head protein 4 homolog A, Radial spoke head-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the flagellar radial spoke RSP4/6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium. Note=Radial spoke.
Protein: RNC_LACPL
Sequence: MITELAAMLKERFGIVFNDPDLLAEAFTQASYVNEHQDQQLKYYERVEFLGDAVLELVVSEYLYKRYKDMPQGKLTRLRAAMVCEESFASFARECDFPQYIRLGKGEQKAHAWERDSLLCDIFESFVGALYLDQGREPVLKFVHQVIFPKLDEGRFDGVFDYKTTLQEYLQRDGDVAIDYQLIEQDGPANERSYEIAVLADGQKIGEGWGHSKKEAEQSAARQAYSQLQQK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AB4G_ARATH
Sequence: MESYTLSTSSISYAKPLSPLLLTAEQPSFILRNITLTSHPSQILAIIGPSGAGKSTLLDILAARTSPTSGSILLNSVLINPSSYRKISSYVPQHDTFFPLLTVSETFTFSASLLLPKNLSKVSSVVASLLKELNLTHLAHTRLGQGLSGGERRRVSIGLSLLHDPEVLLLDEPTSGLDSKSAFDVVQILKSIATSRERIVILSIHQPSFKILSLIDRVLLLSKGTIVYHGRLDLLEAFLLSKGFTVPSQLNSLEYAMEILQNIRDPYENANIALPDHCPESKKQNQKQSIVRYKSSRITEISLLSSRFWKIIYRTRQLLLTNILESLVVGLVLGTIYLNIGTGKEGIRKRFGLFAFTLTFLLSSTTQTLPIFIDERPILLRETSSGLYRLSSHILANTLVFLPYLLLIAIIYSVSLYFLVGLCFSWQALAYFVLVIWIIVLMANSFVLFLSSLAPNYIAGTSSVTILLAAFFLFSGYFISKESLPKYWLFMYFFSMYKYALDALLINEYSCLHNKCLVWFEEASVNSCLVTGGDVLDKNGLHERQRWFNVYMLLGFFVLYRVLCFLVLLKRVSGSKR
What are the official names of this protein?
ABC transporter G family member 4, ABC transporter ABCG.4, AtABCG4, White-brown complex homolog protein 4, AtWBC4.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYE_KINRD
Sequence: MTDIAAPPAPGTSPVRVRFCPSPTGTPHVGLIRTALFNWAHARHTGGTFVFRIEDTDAARDSEESYAQILDALDWLGLDWDEGIGVGGPHEPYRQSLRRPVYDDVVRRLREAGHLYESFSTAEEIEARHEAAGRPKVLGYDGFDRDLTPEQVAAFRAEGREPTLRLRLPEGRDYSFDDVVRGRIEFKAGSFPDPVLVRANGDPLYTLVNPVDDALMGITHVLRGEDLLSSTPRQIALHEALVDIGVSQAVPLFGHLPYVTGEGSKKLSKRDPESNLFHHRDRGFIREGLLNYLALLGWGISEDRDVFSVEEMVAAFDVADVNASPARFDVAKAEAINAAHLRLLAPEDFRGRLVPYLQAAGVLPAQPSPEQLERLAAAAPLVQERMTLLGQAPGMLGFLFVADGDVVLEPDATAALRPEAADVLDASLAALEALTGWTTADLEAALRAAVVEGLGVKPKFAFAPLRTAVTGRRVSPPLFESMEILGRESSLARLRRLRATL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNK_BACMK
Sequence: MGYYSLTETTAIQYAKEHGYFEKKANVVCHEIGDGNLNYVFKLDDGEKSIIIKQALPYAKVVGESWPLSIKRATIESKALQIFAKYVPDYVPVVYSHDEELAVTVIEDLSRLTITRKGLIDGEGYPLLSQHIGRFLAHVLFYTSDFGLQSEEKRVLEGTFVNPDLSKITEDLVFTDPFGHYDTNDYESDLQSVIDELWSDKTLKLKVAQYKYKFLTRKEALIHGDLHTGSIFSSPSETKVIDPEFATYGPFGFDIGQFIANLLLNALSREEEKRSVLFFHIEKTWSYFVENFTKLWIGEGVEAYTKEKQWLPIILQNIFTDAVGFAGCELIRRTIGLAHVADLDGIANKENRIQAKKQALSLGRELIKYEAKCADIQLFRTLFQQTVGGVKA
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase, MTR kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: NEC2_NESMA
Sequence: MAFLSNMAMFITMLMFSSMMHPCFSQPSCAPMDTMDTNGVDEADIDMMQFPINLEFLEAEFFLWGALGHGLDVVAPQLAMGGPPPYGAQKANLDPLTQNIITEFAYQEVGHLRALERTVGGFPRPLLNLSASNFANLIEAAFGYHLVPPFNPYRDGLSYMLASYAVPYMGLVGYVGTNPNLKGHQTKRLLAGLLGVESGQDAVIRMYLYERQGHVVAPYRHTVAEFTARISELRNRLAMCGVKDEGVIVPRQLGAENQTMSNVLSANYDSISYRRTPGEILRVVYSTGNESVPGGFYPNGGNGRIARRFLV
What is the function of this protein?
Involved in the production of blood-red nectar containing the alkaloid nesocodin and that serves as a visual attractant for pollinator visitation, including vertebrates such as Phelsuma geckos (PubMed:35074876).  The nectar is initially acidic and pale yellow, but slowly becomes alkaline before turning into red within 24 hours (PubMed:35074876).  Together with NEC1 and NEC3, facilitates the condensation of sinapaldehyde ((E)-3,5-dimethoxy-4-hydroxycinnamaldehyde) and proline to form nesocodin, a pigment with a stable imine bond (PubMed:35074876).  Protects nesocodin from degradation by hydrogen peroxide H(2)O(2) by catalyzing the degradation of H(2)O(2) into water H(2)O and dioxygene O(2) (PubMed:35074876).
What are the official names of this protein?
Ferritin-like catalase Nec2, Nectar protein 2, NmNec2.
Protein: MED22_CAEEL
Sequence: MSGVAGGASKKSSSRTMATKKLIIDEFKRRLRDNIKSLNDNFFHIIQAAKVNPDDNAYKNQTGKMTEFYTTKNEMAVRAQLMVRASDELLKLTADLKEFLILHDFHFLTHNIKQAEAQCEETLRQQSHQHNCLDSEVSNILFDLEREIAENFYLRHT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 22, Mediator complex subunit 22.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3654_NOSS1
Sequence: MTKSTWHQGELIEVAIADLSDTGDGVGRFAERVVFVPDTVPGDRVLVRLLHVKPNYAHGKLHQLLEPSPHRIRPGCIVADKCGGCQWQHIDYEYQLIAKRHQVIQALQRIGGFAQPPVDPVLVTASSLGYRNKATYPLDVSATGQVQAGYYQKGSHHVVNLNQCPVQDPRLNPLLAQVKQDIQQRDWPIYDEKRHQGQIRHLGLRIGRRTGEILLTLVVKDGNLPGIEQQAQEWLQRYPQLVGVSLNRNPERTNAIFGRETRCIAGVPYLREIFAGLEFQVRPDTFFQVFTETAEALLQVIESQLNLQGHETLIDAYCGIGTLTLPLSKQVRQAIGLELQPEAVQQAIVNAQHNGINNVEFQVGAVEKLLPKMGIIPDVVLLDPPRKGCDRIVIESLLASKPARIVYVSCKVATLARDLKLLCTDGTYTIQRIQSADFFPQTSHVEVAAFLVLSQSGKDN
What are the official names of this protein?
Uncharacterized RNA methyltransferase alr3654.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: RTCB_NEMVE
Sequence: MPRSYKEECSFLERLSDSAFLIKKGFVPNMKVEGKFYINEHLEKLMFDELRHWCGAQGIGGFLPGVKQIANVAALPGIVGYSVGLPDVHSGYGFAIGNMAAFDMSLPEAVVSPGGVGFDINCGVRLLRTNLEEKDVQPVKERLAQSLFDHIPVGVGSKGVIPMGAKDLEDALEMGVDWSLREGYAWAEDKEHCEEYGRMLQADSAKVSAKAKKRGLPQLGTLGAGNHYAEIQVVDEIYNEFAAKKMGIDHKGQVCVMIHSGSRGLGHQVATDALVAMEKAMKRDKIEVNDRQLACAHIKSPEGQDYLKGMAGAANYAWVNRSSMTFLTRQAFAKVFNSTPDDLDMHLIYDVSHNIAKVEEHFLDGRQRQLLVHRKGSTRAFPPHHPLIPVDYQLTGQPVLIGGTMGTCSYVLTGTEKGMTETFGTTCHGAGRALSRAKSRRNLDYQDVLENLAQKGISIRVASPKLVMEEAPESYKNVTDVVDTCHSAGISKKAIKLRPIAVIKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: UB2L6_HUMAN
Sequence: MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPEYPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREPLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins.  Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.  Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
What are the official names of this protein?
Ubiquitin/ISG15-conjugating enzyme E2 L6, E2 ubiquitin-conjugating enzyme L6, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.