PharMolix/UniProtQA huggingface dataset:
Protein: EIS_MYCBO
Sequence: MTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGAGPGSEVVGMALYMDLRLAVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
What is the function of this protein?
Effector that is released into the host cell and affects host immune responses.  Acts as an acetyltransferase that acetylates lysine residues of host proteins.
What are the official names of this protein?
N-acetyltransferase Eis, Enhanced intracellular survival protein, Protein-lysine N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase Eis family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasmic vesicle, host phagosome. Extracellular vesicle, bacterial extracellular vesicle. Host extracellular space.
Protein: UNG_EBVB9
Sequence: MASRGLDLWLDEHVWKRKQEIGVKGENLLLPDLWLDFLQLSPIFQRKLAAVIACVRRLRTQATVYPEEDMCMAWARFCDPSDIKVVILGQDPYHGGQANGLAFSVAYGFPVPPSLRNIYAELHRSLPEFSPPDHGCLDAWASQGVLLLNTILTVQKGKPGSHADIGWAWFTDHVISLLSERLKACVFMLWGAKAGDKASLINSKKHLVLTSQHPSPLAQNSTRKSAQQKFLGNNHFVLANNFLREKGLGEIDWRL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines.  Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG, UNG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: ADH_DROAF
Sequence: MVIANSNVIFVAGLGGIGLDTSREIVKSGPKNLVVLDRVDNPAAIAELKALNPKVTVTFYPYDVTVPLAETKKLLKTIFDKLKTVDLLINGAGILDDNQIERTIAVNFTGTVNTTTAIMDFWDKRKGGPGGVVANICSVTGFNSIYQVPVYSASKAAALSFTTSIAKLAHITGVTAYSINPGITKTVLVHKFNSWLSVEPRVAELLLEHPTQTTLQCAQNFVKAIEANQNGAIWKLDLGRLDAIEWTKHWDSGI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: KPSH2_HUMAN
Sequence: MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL
What are the official names of this protein?
Serine/threonine-protein kinase H2, Protein serine kinase H2, PSK-H2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: RK5_THAPS
Sequence: MRSQQSLEEIAELYGLLENIKKEYEDGIHSVLRKSNPELFSNPHTIPKLKKISINRGLGLAAQNTNILKKSITEFTRITGQKPLITRAKKAVAGFKIREEMELGLSSTLRGEKMYSFLTKLIFFTFAQIRDFRGLSVRSFDKAGNYTFSLKEQLIFPEIEYDDVDQVQGLSITLVLDSSTPKSRSKTVDRVLNGMILLKFLRFPLNDCGYYDKYESFGEITQVWDKKKHLRRKRWSQE
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR3_NANDO
Sequence: MGQKINPLGFRLGTTQSHHSLWFAQPKNYSEGLQEDQKIQDCIRNYVQKNMRISSGVEGIARIEIQKRIDLIQVIIYMGFPKLLIEGRSRGIEELQSSVQKRFNSVNRKLNIAITRIAKPYGHPNILAEFIAGQLKNRVSFRKAIKKAIELTEQADTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDYCSYTVRTIYGALGIKIWIFTDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLPB_YERPE
Sequence: MKFDVIIIGGGLAGLACGIRLAEQGKYCAIVSSGQNALHFSSGSLDLLAKLPDGQAVSQPLSALSALAELAPEHPYSKMRNITQLDELVQEAEALLRRCGLDIVGSSAENHLRLTPLGSCRPTWLSLADIPVAPLNGPLPWQRVAVIGIEGFLDFQPQMVASALQDQGIDATADYLHLPALDRLRDNPSEFRAVNIARILDLPENRQPLADELSRLSSTAEMILLPACIGLDKSAPLDALRAVVGKPIQLLPTLPPSLLGMRLHQALRHRFQQLGGLVMPGDAVLRAELVDNRITGLYSRNHGDIPLRAAQMVLASGSFFSNGLVATFDKIYEPILDLDILSLPHRADWSHSNLFAPQPYLQFGVNTDNHLRPLRGGVALENLHAIGAVLGGYDPLQQGCGAGVSLTSAVFVAEQIISEMAVTL
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: BOR_LAMBD
Sequence: MKKMLLATALALLITGCAQQTFTVQNKPAAVAPKETITHHFFVSGIGQKKTVDAAKICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ
What is the function of this protein?
Not known; is expressed during lysogeny in Escherichia coli.
What are the official names of this protein?
Lipoprotein bor.
What is the protein family that this protein belongs to?
Belongs to the lambda phage bor family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor.
Protein: APT_SHESR
Sequence: MAMNTETLSLIKQSIKTIPNYPKEGILFRDVTSLLENAVAYKATIDLLVEQYRNKGFTKIVGTEARGFLFGAPLALELGIGFVPVRKPGKLPRATISQSYELEYGHDSLEIHTDAITANDKVLVVDDLLATGGTIEATVKLIRQLGGEVQDAAFVISLPDLGGEARLTALGLELVKLCEFEGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNF_SALEP
Sequence: MGVMWGLISVAIASLAQLSLGFAMMRLPSIAHPLAFISGLGALNAATLALFAGLAGYLVSVFCWHKTLHTLALSKAYALLSLSYVLVWVASMLLPGLQGAFSLKAMLGVLCIMAGVMLIFLPARS
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_ALKOO
Sequence: MYAIIETGGKQYRVQEGDTLFVEKLDANQGDIVTIDSVLAVSKDGNLTVGAPMVAGAKVEAKVLEQGKAKKIIIFKYKPKKDYRRKQGHRQPYTKLVIEKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RF3_LIMRD
Sequence: MSPKELAEAVNKRRTFAIISHPDAGKTTITEQLLLFGGVVREAGTVKARKTGNFAKSDWMEIEKKRGISVTSSVMQFDFQGKRINILDTPGHEDFSEDTYRTLMAVDSAVMVIDSAKGIEPQTKKLFQICKMRGIPIFTFMNKFDRDAREPLDLLNEVEDVLGIETYPINWPIGSGHQFKGIYDRFNHRVALTHPADENNPYLPLDEDGNVEGDNPLAGDGEWQDAMDGMELVEVAGNELDQEKIAKGDQTPVFFGSALTNFGVQTFLETYLQFAPAPSDHKTEDGDVVKPLDPEFSGFVFKIQANMNPRHRDRIAFVRICSGEFDRGMDVTLSRTKKPMRLSNVTEFMADTRENVETAVAGDIIGLYDTGNFQIGDSIYNGKKDIQFEKLPQFTPELFVRVSAKNVMKQKSFHKGINQLVQEGAVQLYRSYSTGDYILGAVGQLQFEVFKFRMQNEYNSEVVMEPMGTKTARWIDPDQLDEKMSSSRNILVKDIHDQPLFLFENQFAENWFKQKYPDVKLTAKL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_OPITP
Sequence: MPWTRRHLLTLEELSREEIDQIHATAAAFKRTLSRRVKKVPALRGKTIVNLFLEPSTRTRMAFDMAAKRLSADVISFDAASSSTTKGETLHDTAKNIQALGADMIVIRHAAAGSPLYLSRILDIPVINAGDGAHEHPTQGLLDTFTMKEHLGSLKGRKIVILGDILFSRVARSNIHALTKLGANVTLVGPATLVPHWFTDLGVEVSHDLRTALADAEVVMLLRIQHERQSSGHFPSLGEYTSMFGLNKTRASWLNPKAIIMHPGPINRGVEIDSDLADGDHSVILEQVNNGIAVRMAALYLCAGGQPENVAPIE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL16_BRUC2
Sequence: MMQPKRTKFRKQFKGRIHGNSKGGTDLNFGAFGLKALEPERVTARQIEAARRAITRHMKRAGRVWIRIFPDLPVTSKPTEVRMGKGKGSVDYWACRVAPGRVMFELDGVPEDVAREALRLGAAKLPIKTRFIQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: G3P_BORBU
Sequence: MKLAINGFGRIGRNVFKIAFERGIDIVAINDLTDPKTLAHLLKYDSTFGVYNKKVESRDGAIVVDGREIKIIAERDPKNLPWAKLGIDVVIESTGVFSSATSDKGGYLDHVNHAGAKKVILTVPAKDEIKTIVLGVNDHDINSDLKAVSNASCTTNCLAPLAKVLHESFGIEQGLMTTVHAYTNDQRILDLPHSDLRRARAAALSIIPTSTGAAKAVGLVLPELKGKLNGTSMRVPVPTGSIVDLTVQLKKKDVTKEEINSVLRKASETPELKGILGYTEDPIVSSDIKGNSHSSIVDGLETMVLENGFAKILSWYDNEFGYSTRVVDLAQKLVK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_ZYGCR
Sequence: MTIRSPEPEVKILVDIDPVPTSFERWAKPGHFARSLAKGPSTTTWIWDLHADAHDFDSHTSDLEEISRKVFSAHFGQLAVIFIWLSGMYFHGARFSNYEAWLSDPTHIKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGFFQIWRAAGVTSELQLYATAIGGLVMATLMLIAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQIHVSLPINQLLDAGVDPKEIPLPHEFLLNRDLLAQLYPSFSKGLTPFFSLNWSEYSDFLTFRGGLNPVTGGLWLTDTAHHHLAIAVLFIVAGHMYRTNWGIGHSLREILEAHKGPFTGEGHKGLYEILTTSWHAQLAINLATLGSLTIIVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFCVVGAGAHAAIFLVRDYDPTTQYNNLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHAAAPGFTAPNAAAATSLTWGGSDLVAVGGKVAMMPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFSRSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSVTAKGVSHITGGNFAQSATTINGWLRDFLWAQASQVIQSYGSSLSAYGLVFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRAVGVAHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYRE_PYRAY
Sequence: MKEELMKLIIESGCIKFGHFILTSGKESNYYIDIKSLITNPKALKLIAKMIKEESRKLGIEYDKVAGPELGAVPIATALSLETNKPLLIIRKKRKEHGTGKLIEGEISPGDRVLLVEDVTTTGGSVIRAAKILKEHEAEVVGIFVVVDREEGAKENIEKEGFKLYPLVLVSDLFEAAGVSKD
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RS14_YERPB
Sequence: MAKQSMKAREVVRVKLANKYRAKREELKAIISGVNSSDEDRWDAVLKLQSLPRDSSPSRQRNRCNQTGRPHGFLRKFGLSRIKVRETAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ERA_MYCLE
Sequence: MAEFRSGFVCLIGRPNTGKSTLTNALVGTKVAITSMKPQTTRHTIRGIVHREGNFQIVLVDTPGLHRPRTLLGKRLNDLVRDTYTEVDLIGLCIPADEATGPGDRWIVNQIRSVAPKTILVVIVTKIDKVPKDRLSAQLVAVSDLVADSAEIVPVSAVTGEQVDVLIDVLAAALPPGPAYYSAGELTDEPEELLMAELIREAVLEGVHDELPHSLAVVIDEVSPRAGRGDLIDVHAVLYVERPSQKGIVIGKSGARLREVGIAARRQIEKLLGTNIYLDLHVNVAKNWQRNPKQLGRLGF
What is the function of this protein?
Exhibits GTPase activity.  Binds RNA but is probably not involved in ribosome assembly in mycobacteria.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: Y2154_ENTFA
Sequence: MKEKMSVKTIVAIGIGSAVFVILGRFVVIPTGIPNTNLETSYPFLALMSVVFGPVAGGLIGLIGHTLKDFTTYGSAWWSWIICSGIIGIIFGFAGRKMDLQHGEFTTNDMVRFNIFQAFGNIVVWGLIAPSLDILIYSEPASKVFTQGVFATVSNIVAVGIIGTLLMKAYASTRTKKGSLSKD
What are the official names of this protein?
UPF0397 protein EF_2154.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPC_KINRD
Sequence: MTVLDDILAGVREDLAARKALTTLDELKERAHRQVPAKDAQGLLKPRDAEQRGVKVIAEVKRRSPSKGALATIPDPAALAEQYELGGATVISVLTEQRRFGGSLEDLRAVRCAVDVPVLRKDFVVDSYQLWEARAWGADVVLLIVAALEQEALVSLIERTRSLGMTALVEVHTAEEVARALDADARVVGVNNRNLKTLEVDNATFADLAPLIPDHVVRIAESGVSGPRDVVEFARAGADAVLVGETLVRGEDPRRAVADLVAAGAHPAVQAVRP
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LEUC_GLUOX
Sequence: MPVTNSPRTLFDKIWDDHVVERLEDGTCILYIDRHLVHEVTSPQAFEGLRMSGRRVRRPDATVAVADHNVPTSDRSKPIEEPQSRLQIETLEKNVAEFGVPYFPLRSASQGIVHVVGPEQGISLPGMTIVCGDSHTSTHGALGSLAFGIGTSEVEHVLATQTILQKPAKNMRVSVEGKVGPGVTAKDILLAIIGRIGTAGGTGHVIEFAGSAIRDLDMAGRMTLCNMSIEAGARAGLVAPDETTFAYVKGRPFAPKGEAFEQACDYWRSLASDDGAYFDTEVTLAAEEIIPSVTWGTSPQNVLPIDGSVPSPSDEPDPARAAQIQRALDYMGLEAGQKIAGTPVDVVFIGSCTNSRLEDLRAAADVVRGRHVAEGVRAMIVPGSGLVKHAAEAEGLDKVFLDAGFEWREAGCSMCLGMNPDRLTPGQRCASTSNRNFEGRQGPDGRTHLCSPAMAAAAAVTGRLCDVRELVKETV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: DNAJ_STRMK
Sequence: MSKRDYYEVLGVARTATDDELKKAYRRCAMKFHPDRNPGDAAAEASFKECKEAYEVLSDGNKRRMYDSHGHAAFEHGMGGGGPGGPDMNDIFGDIFGNIFGGGGGGPRQARRGADIGYVMELDLEEAVRGVERRIEIPTLAECGDCDGSGSEDGKVETCNVCHGRGQVRIQRGIFAMQQACHNCGGRGQIIAKPCKTCHGNGRVEEDKVLSVKVPAGVDTGDRIRLQGEGEAGPAGTPPGDLYVEVRVREHAIFQRDGDDLHCEVPIRISQAALGDTVRVATLGGEAEIRIPAETQTGKLFRLRGKGVRSVRSRSEGDLYCRVVVETPVNLTPEQRKLLEQFEATFVGEEARKHSPKSATFMDGVKGFWDRMTS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLP2_PINMA
Sequence: MKPFISLASLIVLIASASAGGDDDYGKYGYGSYGPGIGGIGGGGGGIVIGGGGGGIGGGIGGGIGGGIGGGGLIGGGGLIGGFGPGSVSGSVNQFGGVRTRAFGLGGTSPAVRGAAQGAATLSALGVASGRPSRVSGVSVGTGGGRALVSGSATPIGGYGIGIPYGVYGGGYGGYGGGYGGYGLGYGGYGGGYGGYGYGGYGYGPDLATFQGHTFGNLATGSINSLTGGYQIPYGGILSLYGPYGGYGGGYGGYGGGYGGYGGGYGIGIGSGGLGYGGYGYGGYGLGGSTLTGVSQSGPFGTASMYGQAYGAGVPLFGTTYFGGVNVGSPYGIYGGGYPIGGIGGGAGPIGGGGIVIGGGVGGIGGGGIGGIGGGGIGGGGIIGGGPIIRKKKY
What are the official names of this protein?
Shematrin-like protein 2.
Protein: HTPG_BURM9
Sequence: MTQQTMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALENNALYESDPNLRIRLSFDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDFQVDTIERAARGTTITLHLREGEDELLSSYRLKSIVQKYSDHVALPILMKKEEWDQEKGEMVEKDEDETINQASALWTRAKSEVTDEQYKQFYQHVAHDHQDPLAWTHNRVEGRSEYTQLLFVPSHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYLRFIKGVVDSSDLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWSAFGQVLKEGVGEDHANRERVAKLLRFASTHGDTDAQDVALADYVARMKPEQTKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHEFDGKPLASVARGDLDLGALNDDEKKAQEETGEAMKPVVDKMKETLGEKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRMLKAAGQSAPSFQPILEINPEHPLVKALKADGADFGDWCHLLFDQALLAEGGALEDPASFVKRTNALLLSRAA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_AKKM8
Sequence: MTDPERTIAAQATAAGQGAIAVIRMSGPGCMDILKQCTPAAFTERLRPRRATLVCIRDAEGAAIDQALVTWFPAPASYTGEDTAEISCHGGMLVTDRLLKRLYQCGASPAEPGEFTKRAFLNGRMDLTQAEAVMDVISAGSDLALKAAQSQLDGGIGAQVDELKDNLVHVLAHIEAYIDFPDEDISPDTASDLLARLRNMEEKLDTLLKTAEGGRLLREGIRTAIAGPPNVGKSSLLNTLLGYDRAIVSNIAGTTRDTVEESIQLAGLALRLIDTAGVRESSDVIEQAGITRTNRALETADLVLEVADASTPRVKDFPAPVLTAPRLLILNKCDLGIHPDWKAVPGIRFSCATGEGRKELEEAIIQAFSSSLPGETGSSLVAINARHQHELGLCREHVRLASESISRQESPEFTALELREALTHLGEITGAVDTEDVLGAIFSSFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIF1_BOVIN
Sequence: MSETRDLQGGKAFGLRKAQQEERINEINQQFLDDPKYSSDEDLPSKLEAFKKKYMEFDLNEDGGIDIMSLKRMMEKLGVPKTHLELKKLIMEVSSGPGETFSYSDFLKMMLGKRSAILKMILMYEEKAREQEKPTGLPAKKAISELP
What is the function of this protein?
May play a role in macrophage activation and function.
What are the official names of this protein?
Allograft inflammatory factor 1, AIF-1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, phagocytic cup. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Protein: YIDC_PARD8
Sequence: MDKNTLIGFLLIGVVLFAFSWFNRPTPEQLEAQRRYQDSIAKIEYAQQLELQKQENKSALVEDSLENLPDSVRAQRLQQSFGVFGDAMVGTEDYTTLQNDVVELRISNKGGRICYARLKEYDTYNDEPLVLFDEKESNFNFTLVTATNRVVNTSDLYFTPVKGNDPNSVIMRLNTGEGSHLDFTYTLKPDDYMVQYQILGTGLNGVLAPSTNALDLLWEQDIRQQEKGRKFEDRYVTLNYKFMADDVEHLSESKSDSKQIPNRLKWIGYKDMFFSTVLISQEGFEATTLDSKAIPEGDVLKQFKTTASVPFDLQGKEATNLSFYFGPNKFALLKSFDKGVSAEQQLDLEKLVPLGWGIFRWVNQYFVIPLFDFLGKFIHNYGILILLMTIIVKIILFPLTYKSYMSSAKMRVLRPQVEEINAKYPGQDKAMERQKATMELYSRAGASPMSGCLPMLLQMPILIALFMFFPSAIELRHQSFLWAHDLSTYDAIFSWNKYIPIITPYFGNHISLFCLLMTITNIFYTKYNMEMTNTGQQQMPGMKAMMYMMPLMFLVFFNQYASGLTYYYFISTLITIVQTLIFRYTINEDKLLAKLEANKRKPMKKSGFMKRLEEAQRAQQETLRKQQEAKKKR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HISZ_SYNJB
Sequence: MYGRGSGAEHSRGSGAEHFWDPRPEASSTVSSSLRPPSGARDLLPREVQRREKLEAQLTRVFRRHGYQRIITPTLERLETLLAGGSIRAESVLQLRDGEGTMLGLRPEFTASIVRAAATRLAGGPLPLRLYYHGSVFRNSRREEGSYSSQEFFQSGVELIGAGGWLADAEILLLLADCIRSVGISSCEFSWTLLLGDVSLTESLLSAVAPTAQAAVRRAIAQLDYVYLESAPLPEAARQIGLQILGLRGQPGSVLSDLAQLPVPPERLRDLRQLCQVLEEHGVRVVLDLSLLQTLAYYTGIVFQAVASGEIIALGGRYDRLYALYSPQQVEQPGIGFTLLPDTLLRLLPPDPQTEEMGCKRLVVPLVPAGIPAALALAARWREECTAPLTRTEAVELELLDRAPEEIEAYARQCRIPEIAWVQADGSYHITHPG
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.