PharMolix/UniProtQA huggingface dataset:
Protein: YQGF_MYCUA
Sequence: MVAASHRSPDRPGDPEGLEPGTGRGRRLGIDVGTVRIGVASSDPDGILATPLETVRRERSGKHLRRLATLVGETEAVEVIVGLPRTLADRIGSSAQDAIDLADELAARVAPIPVRLADERLTTVSAQRSLREAGVRAKNQRAVIDQAAAVAILQAWLDQRRTLAGGRADG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP8_RAT
Sequence: MDFHSCLYDIAERLGNEELAALKFLCLDHIPQKKQESINDVLVLFQRLQEEGMLEEDNLSFLKELLFHISRRDLLSRVLKSSPEEMVRELQVLGKAQVSAYRVMLFKLSEDMDKEDLKSFKFLLITEIPKCKLQDNSSLLDIFVEMEKRTILAENNLVTLKSICFRVNRSLLGRIDDYERSSTERRMSTEGGEELPVSVLDEVTIKMQDMWDSPGEQESESLNSDNVYQMKSKPRGYCLIFNNNNFSKAREDIPKLSNMRDRKGTNYDEEALSKTFKELHFEIVSFSDCTASQIHEVLVSYQSKDHKGKDCFICCILSHGDKGIVYGTDGKEASIYELTSYFTGSKCPSLAGKPKIFFIQACQGNNFQKAVPVPDETGLEQEHVLEEDSSSYKNYIPDEADFLLGMATVKNCVSYRDPTRGTWYIQSLCQSLRERCPRGEDILSILTGVNYDVSNKDNPRNMGKQMPQPIFTLRKKLFFPPN
What is the function of this protein?
Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood (By similarity).  Initiator protease that induces extrinsic apoptosis by mediating cleavage and activation of effector caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death (PubMed:10197541).  Cleaves and activates effector caspases CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10 (By similarity).  Binding to the adapter molecule FADD recruits it to either receptor TNFRSF6/FAS mediated or TNFRSF1A (PubMed:10197541).  The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation (By similarity).  The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases (By similarity).  Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC (By similarity).  In addition to extrinsic apoptosis, also acts as a negative regulator of necroptosis: acts by cleaving RIPK1 at 'Asp-325', which is crucial to inhibit RIPK1 kinase activity, limiting TNF-induced apoptosis, necroptosis and inflammatory response (By similarity).  Also able to initiate pyroptosis by mediating cleavage and activation of gasdermin-D (GSDMD): GSDMD cleavage promoting release of the N-terminal moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis (By similarity).  Initiates pyroptosis following inactivation of MAP3K7/TAK1 (By similarity).  Also acts as a regulator of innate immunity by mediating cleavage and inactivation of N4BP1 downstream of TLR3 or TLR4, thereby promoting cytokine production (By similarity).  May participate in the Granzyme B (GZMB) cell death pathways (By similarity).  Cleaves PARP1 and PARP2 (By similarity).
What are the official names of this protein?
Caspase-8, CASP-8.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PPR18_HUMAN
Sequence: MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGLRTKALIVDESCRR
What is the function of this protein?
May target protein phosphatase 1 to F-actin cytoskeleton.
What are the official names of this protein?
Phostensin, Protein phosphatase 1 F-actin cytoskeleton-targeting subunit, Protein phosphatase 1 regulatory subunit 18.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm, cytoskeleton. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm, cytoskeleton.
Protein: HSCB_RICAE
Sequence: MQNYFQLLGLPQEYNINLKILEKQYFAMQVKYHPDKAKTLQEKEQNLITAAELNNAYSTLKDALKRAEYMLLLQNINLNDEKTRSLLSPLELSIFWDEMEIIENTILFSDLEKIKDKYELMKKLEIDSLKQAFEEQNLLDATIKTSKLKYIGTLLHKLQEKIKSCK
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: REX_SYNFM
Sequence: MKFAKIPMATIIRLSIYMRTLQELLEDDVDVISSERLAKQCGVNPAQIRKDLAYFGEFGVRGVGYRVNELVNQIKEILGLNRPWNLAMVGLGNLGSALIRHGNFIKHGYMFTAAFDVDPQKVGKRLPNGLVINHVDELEDVIKEREVHVGIITTPASEAQSVANQLVLAGINGILNFAPVQIQVPDCCHVENVDFTIKLDSIAYHLSFGS
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAN2_CHAGB
Sequence: MDADWDEVTRIAFPAPGSNDYPRPATALAFDTIAELLWAGNDRGRVVSFYGRDLQRYTAFKIHPPSEGPVRQFLFHDKGVIALGTRSVHMAMRRGPTLWNIRHDEMENLQCMSFTSKGASEIIVAGFQDTMFVIDVVKGEIVKQKSKYICAATRTGCVDLLDPITFKTVRSWQAHASYINDMDAQNDFIVTCGGSLKQQAAQTYMLDPYVNVFDLKNMTSMKPMPFPPLAAHVRLHPRMLTTSIVTSQHGQMHVVDIMNPNTSNVRYANVMSFINLFEIAPSGEALAMADTECNIHLWGSPSKIHFTDMAIPIEMPKAEEPAPMLDWSPDTPLSSIGMPYYREQLFSAWPSDIISDIGAPPVQLDPSFLASLKQMEWGFYGRNSRGLRRNQVEDTRACMKPSMQPPKFLSEKARESAMSYSAAVPDPKVEQVPESSTDELESLKPEAPPIYRNLEIKYSKFGVDDFDFGYYNKTQYAGLENHIPNSYANSLLQLIHYTPLLRNMALQHAATACVTDLCLLCELGFVFDMLQKAEGSTCQATNMFKALGATPQAAPLGLLEEETHVPSLSTMSQGLSRFLFDRINHDYRSINPISTTLEQTLFNLPQPPTPDELVSRVLATSAVVTIKCMNCRSETTRPGTAQVNDLMYPPPKGSARGGRMHKTTFSQVLKTGVERETASKGWCSRCQRYQNLQMRKTIHSVPAVLAINSAISSQEHRKLWATPGWLPEEIGIIVDQGQFFCFEGEDLKLHLQRGMHNITVYSLIGMVVNIESSSPQKTHLVSVINVAHADAAPSAESKWHLFNDFSVRPISTAEALTFNAAWKLPAVLLFQVKAANNKTNMDWKTKLDTSLLYQDLTPHSDEKTYHVLDLEAEPPGPDTIVGLDTEFVSLKQPEIQMNSDGERETIRPMSHALARVSVVRGQGEHEGEAFIDDYIAIREPVVDYLTLYSGITPGDLDPRTTKHNLVSLKVAYKKLWVLLNLGCKFLGHGLRQDFRVINIQVPRAQVIDTIQVFYLKARLRKLSLAFLAWFLLKEDIQLETHDSIEDARTALKLYRKYLEFEDAGILEAMLEDIYKVGRATNFKPPRKDDQVIQRTDTPFLSR
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NBP6L_BOVIN
Sequence: MGLLETNQYLHSQLEKSKQDFRDLTEKLLTSQATVYSLAKQLQKYKCEEYKDLIESVLEEEAPFEEGNLAEKRRLATGLGRYDSLIEAQARELTCLRQKIQEGEGVCHLFTQHAKNTIKTFESFIKTTDMTYYQRQRFCELLAQGSQMAERLASKLSTENHHDRKDEEGQESLAARLSMGLQGEEVNEVLEDSLDEKYLTHSSHHDSHRPPSSIASVCDVQDQL
What are the official names of this protein?
Neuroblastoma breakpoint family member 6-like protein.
What is the protein family that this protein belongs to?
Belongs to the NBPF family.
Protein: RT10_CAEBR
Sequence: MLNIANTIRSTLLRSKTRNVRTLAATVNPAEQQQVQAVLPDKLYSSIEIEYRGHDKAVLKSYTTFLQQVCKHLEIPQGRLEVLPYIRWVQPALRSKFVHKKYKLHYETRTHITKLEILNVTGSTASTFLEYIERNIPEGVGMRVGFTELQPLPLTIQN
What are the official names of this protein?
Probable 28S ribosomal protein S10, mitochondrial, MRP-S10, S10mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TOLB_AGRFC
Sequence: MKIFSPIRLVLAIAALMSVFSAPAFARVEININKGNVEPLPIAITDFMSSDGIGAQVSAVIAADLQRSGLFAPVNKNAFIEKISNPDQQPRFEDWKVINAQALVTGRVTRESDGRLRAEFRLWDTFAGQQLSGQQFFTQPENWRRVAHIIADAIYERVTGEKGYFDTRVVFVSESGPKTARKRQLSIMDQDGFNVRNLTNSNDIVLTPRFSPNRQEVTYMSFEGQQPRVYLLQLETGQREVVGNFPGMTFSPRFSPDGQKVIMSLQQDGNANIYTMDLRSRTTTRLTNTAAIDTAPSYSPDGQRVAFESDRGGRQQIYVMNADGSGQQRVSFGDGSYSTPVWSPRGDLIAFTKQSGGKFSIGVMKTDGSGERILTSGFHNEGPTWAPNGRVLMFFRQNAGAGGPQLYSIDLTGYNEQLIKTPTFASDPAWSPLLD
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MDL1_SCHPO
Sequence: MDPIRFGLSRVPFAHCYNKRVIFRANYLVPLTWLKNNVAYKSTNTLLLPTPNAEYYSTSKLSSQVNVSLNSLSQKASSGSKIYPFKNSFPLPFSRSILPIRSLAFLKLCVRHNSTVPSKDEQAQDISKINTNGTLQTPNKKVNVFRLFTLARGQGWNFFIAGSLLLVSSGVTMSIPYIVGKILDAGSSGDSSVTHIMGIPSGTFYIGLLGLFFLGSACNFGRIITLRLLSERIVSRLRARLFAKCMSLDGAFFDFHKHGDLISRLTTDSSIVGKSLSMYLSDGLRSSVSAIAGIGMMLYVSMRLTGYMSLIVPPIALGAFFYGEYVRKLSRTTQDALGDLTRVSEEKLANVRTTQAFLGERQEVNRYNDYIRNLFVLAKREAFASGIFFGSTGFLGNATVIAILALGGRMVAAGDITVGQLSSFLLYTVYAGGSIVGLSGCFTDIMKGLGAASRLFELLDAKPKIAPTVGIPVPVTVGKAILSFRNVGFAYPTRPSASIFDNLSFDIHPGTNVAIVAPSGGGKSTISQLLLRFYAPSSGKILADGVDISTYNVHQWRSHFGLVGQEPVLFSGTIGENIAYGKSNASQEEIEDAAKRANCSFVLSFPEKWSTQVGTRGLQLSGGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMHNRSMTTITIAHKLATIRRADQIIVVGDGKVLEQGSFERLSRPGTNFYKLMRWQLGKVEP
What is the function of this protein?
Mediates export of peptides generated upon proteolysis of mitochondrial inner membrane proteins.
What are the official names of this protein?
ATP-dependent permease MDL1, mitochondrial, ABC transporter mdl1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FB94_ARATH
Sequence: MSGKTSSRGQQDEISGEKHEPTPTKEIKRRRKEFEKIHIPNEIVEEILVRLPVKSLTRFQTVSKHWRTLITSKYFGKRHMALEKSKGCKLLFVCDDFVDRAEDTLFLKTVALEKTSVSEGDEQAFEFEGYKGFLDISESCDGLVCFYDTTRAVEVMNPATTMFIELPLSRIQQLCIYKPNPEVELEPVQDPNPVLDPVMTCSQIGVGKDSVSGSYKLVWMYNTSPATPPTCEVLDLDGKKWRFVNTTSLDHHQILCDQRPVFANGSLYWLTGDEEGYATTQTKLIVLDLHTEMFQVIQTPPFITRDASGDKIGLCNLDGRLCISELKKDCKQEF
What are the official names of this protein?
Putative F-box protein At2g02030.
Protein: PSMA1_STAAB
Sequence: MGIIAGIIKVIKSLIEQFTGK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 1 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: COAD_CLOK5
Sequence: MSRAIYPGSFDPITNGHLDIIDRASKVFDELIVGVLVNPDKKGLFTVEERVELIERVVKDIPNVKVESFSGLLIDFMKKKQSQVIVKGLRAVSDFEYECQMSLMNKKLDPNIDTVFMMASAMNSFLSSSSVKQVAMFGGCIEGLVPEEVIIDIIKKFDKAYKNC
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_BLOFL
Sequence: MVRIRLARGGCKKSPFYYIVVTDSRNSRDGRFIERIGFFNPVELDIKKRLRVNLDRVRYWLSNGAQPSDRVFVLIKWSKNVY
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NUOK_RICBR
Sequence: MRILNMNEYIGLNHYLILSSLVFTIGMLGLFMHRKNIINILMSIELMLLAVNINFVAFSVYMQELSGQIFSIIILTIAAAETSIGLAILLIYFRNKGSIEVTDINQMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRP18_YEAST
Sequence: MDLDLASILKGEISKKKKELANSKGVQPPCTEKFQPHESANIDETPRQVEQESTDEENLSDNQSDDIRTTISKLENRPERIQEAIAQDKTISVIIDPSQIGSTEGKPLLSMKCNLYIHEILSRWKASLEAYHPELFLDTKKALFPLLLQLRRNQLAPDLLISLATVLYHLQQPKEINLAVQSYMKLSIGNVAWPIGVTSVGIHARSAHSKIQGGRNAANIMIDERTRLWITSIKRLITFEEWYTSNHDSLA
What is the function of this protein?
Component of the U4/U5/U6 snRNP, binding principally to the u5 snRNP.  It is not absolutely required for the second step of pre-mRNA splicing at low temperatures but is required at higher temperatures.  It may stabilize a particular conformation of the U5 snRNP or orient the U5 snRNP within the U4/U5/U6 snRNP or within the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor 18.
What is the protein family that this protein belongs to?
Belongs to the PRP18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOH_ECO81
Sequence: MSWISPELIEILLTVLKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBA2_SYNS3
Sequence: MTTTIQQRSGANGWQQFCDWVTSTNNRLYVGWFGVLMIPTLLAATTCFIVAFIAAPPVDIDGIREPVAGSLMYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPFQLVVFHFLIGIYAYMGREWELSYRLGMRPWICVAYSAPVAAASAVFLVYPFGQGSFSDAMPLGISGTFNYMLVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGVSTMAFNLNGFNFNQSILDGQGRVLNTWADVLNRAGLGMEVMHERNAHNFPLDLAAAESTPVALQAPAIG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 2, PSII D1 protein 2, Photosystem II Q(B) protein 2.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MSRP_ECOK1
Sequence: MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKALEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILNVQRQPTLLFNGYAEQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: Y809_STRP6
Sequence: MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQPWKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDDLIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTTNGILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR
What are the official names of this protein?
Putative NAD(P)H nitroreductase Spy0809.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: LUXS_HALH3
Sequence: MTQMNVESFNLDHTKVKAPYIRLVGVTEGDKGDKIYKYDIRVKQPNQEHMDMPALHSLEHLMAENSRNHHDRIIDIGPMGCQTGFYLAVLNDDSYENILQVVENTLKDVLNATEVPACNEVQCGFAASHSLEGAQELARELLNKRNEWTEVF
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: FLIG_ECOL6
Sequence: MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV
What is the function of this protein?
FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliG.
What is the protein family that this protein belongs to?
Belongs to the FliG family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body.
Protein: MNME_CAMJE
Sequence: MSDTIAAIATAHGVGSISIVRLSGERALEFALKLSHKTKLTPRHATFTKLFNQNNEIIDEAIMIYFKAPYSFTGEDIVEFQTHGGFSVSEVLLEELVSLGARLALAGEFSKRACLNGKMTPLKALNIQDLILSKSALAAKIIARNMQGNLGELLEKIRTDLVKTLAFVETSIDYADDDLPSDLLEQISTMCEENSKILKEIYTLSQSKKGLIEGFKIAIVGKPNVGKSSLLNALLSYERAIVSDIAGTTRDTIEENFKLGTHLLRIIDTAGIRESKDVIEQIGVALSKKSLEDADIILAVFDASRVQDKEDEKIFDLLANTDKKIFWILNKSDLENVFKNTQNKNFIKLSAQKDITLLKEELQNYLNSFDSEGIMVSSLDLINACKISSEAIFRAKGLLEESSLEFFAFELNLAINELARFTKDFQRDEILDEMFGNFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITD_LEUMC
Sequence: MEIKKTAIAGTLESSDVQIMLSKGTVGVEFDLVSDVAKQFADDIKSTIKETLGLYGIENAVVKVVDKGALDMVIKARTLTAIQRALDAVDQPNWEVL
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R9BP_XENTR
Sequence: MAAPEVSSAGPNMLHPNSRTLTLRGKRGHAAEDSSQGAVSDCKKMHSSLNKVTACYRQLVLCVGGTSDCTRLREELEESRKKAFDLSTDLSNTLMVLLMNEGVSQEDRVELERIWVLFLSTLEFFQQDLCKAHHLCQLFPLHGRRKRLVNTGVIGKTSEVAYRARNIKSPSSSRMHENQQRTERPCSPDLAGQIEHMERMLHDMQMKVSIPIWTVEATEEAWAEVASTCDLDECSDNEILAGEDITSRGCCAHGQSLPGPLCMVS
What is the function of this protein?
Regulator of G protein-coupled receptor (GPCR) signaling.  Probably acts by regulating the activity of some 'R7' family protein (RGS6, RGS7, RGS9 and/or RGS11).
What are the official names of this protein?
Regulator of G-protein signaling 9-binding protein, RGS9-anchoring protein.
What is the protein family that this protein belongs to?
Belongs to the RGS7BP/RGS9BP family.
Protein: PAP1_VACCT
Sequence: MNRNPDQNTFPNITLKIIETYLGRVPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFFSDVDTSASEIKDRILSYFSKQTQTYNIGKLFTIIELQSVLVTTYTDILGVLTIKAPNVISSKISYNVTSMEELARDMLNSMNVAVIDKAKVMGRHNVSSLVKNVNKLMEEYLRRHNKSCICYGSYSLYLINPNIRYGDIDILQTNSRTFLIDLAFLIKFITGNNIILSKIPYLRNYMVIKDENDNHIIDSFNIRQDTMNVVPKIFIDNIYIVDPTFQLLNMIKMKTQIDRLEDLSKDPEKFNARMATMLEYVRYTHGIVFDGTRNNMPMKCIIDENNRIVTVTTKDYFSFKKCLVYLDENVLSSDILDLNADTSCDFESVTNSVYLIHDNIMYTYFSNTILLSDKGKVHEISARGLCAHILLYQMLTSGEYKQCLSDLLNSMMNRDKIPIYSHTERDKKPGRHGFINIEKDIIVF
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L, VP55.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: HFQ_CROS8
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGSNNYHHSNNAQPSSAASQDSEDAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.