PharMolix/UniProtQA huggingface dataset:
Protein: GATD_HALSA
Sequence: MTADPGDRVRVTHGDASHEGVLVPSPSDDHLVVKLDSGYNVGVDTADADIDVLDADAVTVDGDTGEDAAGSTVEFDDDLPTIALISTGGTIASTVDYRTGAVTAQFDAEDVLRAVPDLAGRANYRGRVVANILSENMEPSIWQDLAAAVREEIEAGADGVVVMHGTDTMQFSASALSFMLETPVPVVFTGSQRSADRPSSDNVMNAVCAVEAAKSDVAEVMVCMHATESDDRCALHRGTRVRKTHTSRRDAFETVGATPLGYVDYDAASEAATADARGVTVEGAHAARGDATLDVASALEPAVELVKFTPGMNESLLAACEGSAGVVIEGTGLGHVHSDLTDTIGSLVDDGTTVVMTSQCLEGRVCDRVYDTGRDLLAAGVVEAGDTLPGTAKVKLMWALANADDPEAAMQESVAGALTTQSRPWTA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit D, Glu-ADT subunit D.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family. GatD subfamily.
Protein: VAPB6_MYCTO
Sequence: MSVTQIDLDDEALADVMRIAAVHTKKEAVNLAMRDYVERFRRIEALARSRE
What is the function of this protein?
Antitoxin component of a possible type II toxin-antitoxin (TA) system.  The cognate toxin is VapC6 (By similarity).
What are the official names of this protein?
Putative antitoxin VapB6.
Protein: HIS7_OLEA2
Sequence: MTRRAATVTRTTTETAISLSLTVDGKGEVSVTTGHGFTDHMLTLLGFWAGFDLTLTCNGDTHVDAHHTVEDAGLCLGQAFAQALGDRKGIARVGNARVPMDEALTEVDLDISGRPYLVYRGDELLPPVIAGDEADLWREFFKSFANGARINLHISLLYGKNGHHLLESAFKGLGLALRRAAACEREALLSTKGSLD
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y883_LAWIP
Sequence: MNTTIIWHGHSNFQINANGISVLIDPFFTNNPRCTKNWNEIQKPDIVLITHDHSDHLGDAIAICKSTGALCGCIVGTADKLIQQGMPQHLIIGEIGFNIGGTIERKGVRITMTQSFHTSESGSPAGYIITMPNNFTLYHPGDTGIFQTMKTFGKLYNLHLSLLPIGGFFTMDSYQAAYAAKMLKCKMVIPMHWGTFPVLEQTPERFKNYLKAMAPECKYIAMEPNTSKEL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase LI0883.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: LOLA_BLOFL
Sequence: MKLFIYFFCLIVFLSSSICVVHSLEPYCVLKNRLNLINNLYVHFVQKINFCNMKEIELIRGELWIKRPNLFYCHVMGSQESFLISDGKTLWFYVPTIKQVTAYCLENIISNNVFLQLLFMSNTNIWQDYTITQKKDWFYFKSSYDDGKHIKQFKIKITDRGIIDQFSIIQENKQHIDYYLSNQCVNLINQDKFCFTLSDDIQLDDQRMKF
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL19_AZOPC
Sequence: MDLIKVVEQRFADLTQKAYPHFKSGDTITVAYRIKEGNKERIQQYRGVVIKMAGHGSSKRFTVRKMSENIGVERIFPINSPFIDNIVLNKIGKVRRSKLYYLRKLIGKKSRIKEKRI
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: HIS7_GLOVI
Sequence: MEPRIASTVRTTRETDIQIRLDLDGTGRVQAETGVPFLDHMLAQIATHGLIDIDVSAQGDLHIDDHHTNEDVGIAFGQCLAKALGDKRGISRFGHFAAPLDEALVQVVLDLSGRPHLSYGLEIPTQRVGSYDTQLVREFYQAVVNNSSMTLHLRQWAGINSHHIIEASFKAFARALRLAVEIDPRRAGSLPSSKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_SYNFM
Sequence: MKTTRTEAIILNTRDHGESDRLVGLYTRSGGRLQGIAKGARRSRKRFANTLEPCSLVELQFREKGTLVWLESCKLLEPFLSLRTELIRWGIAALISEIVIEMVPEGDPQPELFELLKETLRQLCEDKDSLNVALLFIFRFQDKMGYLPALENCGICGRSLRSATKWCWQVDRGLLACPDHPVERVRALELDLGTLLLIRQCRSLSLDRIWRLRFLHDTKVQLFYGLLDWVRGHIRKELKSLKLLQQAHST
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TRIAA_XENLA
Sequence: MNSVGEECTDMKRDYDQCFNRWFAEKFLKGAGSGDPCTELFRRYRECVQKAIKDKDIPVDGVDFMGPSKSKTESDGSS
What is the function of this protein?
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes.  The triap1:prelid1 complex probably functions as a phosphatidic acid (PA) transporter across the mitochondrion intermembrane space to provide PA for cardiolipin CL synthesis in the inner membrane.  Likewise, the triap1:prelid3a complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo).  Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (By similarity).  Required for pronephros development; probably involved at an early stage in the formation of pronephric components derived from the somatic layer (By similarity).
What are the official names of this protein?
TP53-regulated inhibitor of apoptosis 1-A, p53-inducible cell-survival factor-A, p53csv-A.
What is the protein family that this protein belongs to?
Belongs to the TRIAP1/MDM35 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion intermembrane space.
Protein: RS17_PSEFS
Sequence: MAEAEKTVRTLTGRVVSDKMDKTITVLIERRVKHPIYGKYVKRSTKLHAHDETNQCHIGDKVTIRETRPLAKTKSWALVDVLERAVEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: LPXC_BORPA
Sequence: MFRQRSIQNLVRTIGVGVHSGRRVELTLRPAEANTGIVFHRVDLPQVVDLPASAIGVGDTRMASVLQQGNVRVSTVEHLMSALAGLGIDNLHVDLTAEEVPIMDGSAATFVYLLRSAGIVEQNAPKRFIRVLKPIEVREGEGRNEKWARLEPHEGFALAFSIDFRHPAIDSTANFAEIDFATHSYVREIARARTFGFVNEVEALRSMGLARGGSLDNAIVMDEFRVLNSDGLRYDDEFVKHKILDAIGDLYLLGKPLVARYVAYKSGHALNNQLARALLEQQDAWELVTYESQAEAPQAFRHEWKLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RL17_METSB
Sequence: MYHGNAHRRFGRTHEHRKAMFANMCQALIKHEQIVTTLPKAKDLRPVVEKLVTLGKRGDLHARRQAIAQIKDVALVGKLFAVLGPRYKERHGGYTRVLKAGFRYGDNAPMAVIEFVDRDVDAKGKDSGPVFGADQDEAALAS
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: VE2_PAPVE
Sequence: MKMSAASDHLLAAQETQMQCIEKDSRLLQDHACYWGAVRREKLLLYAARTKGLKTIGCVPVPPCSVTAEQAKQAICMQLIVEELLHSPWAKEPWSLTDLSWERYQAAPKGCLKKGARVVEVEYDGNSSNKTWYTAWSTVYVRGTEEEGWETAVCAADGQGIYYCAGMSSKVYFETFETDARRWSRTGHWTVRDNDVIYHSTFGAPPHSRNDRDCIEGFWSDAGERRGSRGSDTTDRALPYPAARQSPICRPVRTGENRSRAVHRQAPYSAPSSPGSSVGPDSPSESSRQVPLVLLPGPSDPAPPSPDSTDVIAEGDKEPERFSILSKPGGQPCLILSGNGNQAKCYRFRCKRYFREHYQHITTTWWTVGERGSERHGDACVLVTFKDSSQRGVFLKRVPLPPGMRAQALTMIADF
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: FH7_ARATH
Sequence: MSFLFRKNGSSSRRKIKEKLRGRHSDRGGKREEDERYGGSGSDLPPPPSPWGFLFPEDFVRIDGNLKAVIVDDEGLDVIYWKKLLELENSGKIRKNPKPRRRGDKSGDGFRRTGADQDDNDDGDDEVGDESIEEAFSFHVKKSQSASSSGGEIRDQSNNGGGGGGGGGGGGRYYTSSSASPSRPSSSSASAASPSRTSYATSAGSDYGGGGGGKQSQSKFQAPGGGSFPSSPSQIHSGGGRSPPLPLPPGQFTAGNASFPSSTQPPPGQYMAGNASFPSSTPPPPGQYMAGNAPFSSSTPLPPGQYPAVNAQLSTSAPSVPLPPGQYTAVNAPFSTSTQPVSLPPGQYMPGNAALSASTPLTPGQFTTANAPPAPPGPANQTSPPPPPPPSAAAPPPPPPPKKGPAAPPPPPPPGKKGAGPPPPPPMSKKGPPKPPGNPKGPTKSGETSLAVGKTEDPTQPKLKPLHWDKMNPDASRSMVWHKIDGGSFNFDGDLMEALFGYVARKPSESNSVPQNQTVSNSVPHNQTYILDPRKSQNKAIVLKSLGMTKEEIIDLLTEGHDAESDTLEKLAGIAPTPEEQTEIIDFDGEPMTLAYADSLLFHILKAVPSAFNRFNVMLFKINYGSEVAQQKGSLLTLESACNELRARGLFMKLLEAILKAGNRMNAGTARGNAQAFNLTALRKLSDVKSVDAKTTLLHFVVEEVVRSEGKRAAMNKNMMSSDNGSGENADMSREEQEIEFIKMGLPIIGGLSSEFTNVKKAAGIDYDSFVATTLALGTRVKETKRLLDQSKGKEDGCLTKLRSFFESAEEELKVITEEQLRIMELVKKTTNYYQAGALKERNLFQLFVIIRDFLGMVDNACSEIARNQRKQQQQRPATTVAGASSSPAETPSVAAAPQRNAVRFPILPPNFMSESSRYSSSSDSDSES
What is the function of this protein?
Might be involved in the organization and polarity of the actin cytoskeleton.
What are the official names of this protein?
Formin-like protein 7, AtFH7, AtFORMIN-7.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
Protein: RK14_PHAAO
Sequence: MIQPQTLLNVADNSGAQKLMCIRIIGTGNHRYAHLGDVIVAVIKEAVPNMPLERSEIIRAVIVRTCKELKRDNGMIIRYDDNAAVIIDQEGNPKGTRIFGAIARELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AKA7G_RAT
Sequence: MERPAAGEIDANKCDHLSRGEEGTGDLETSPVGSLADLPFAAVDIQDDCGLPDVPQGNVPQGNPKRSKENRGDRNDHVKKRKKAKKDYQPNYFLSIPITNKKITAGIKVLQNSILRQDNRLTKAMVGDGSFHITLLVMQLLNEDEVNIGTDALLELKPFVEEILEGKHLTLPFHGIGTFQGQVGFVKLADGDHVSALLEIAETAKRTFQEKGILAGESRTFKPHLTFMKLSKAPMLWKKGVRKIEPGLYEQFIDHRFGEEILYQIDLCSMLKKKQSNGYYHCESSIVIGEKDRKEPEDAELVRLSKRLVENAVLKAVQQYLEETQNKKQPGEGNSVKAEEGDRNGDGSDNNRK
What is the function of this protein?
Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures.  The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium (By similarity).  Isoform Delta may be involved in shuttling aquaporin-2 (AQP2) to the plasma membrane.
What are the official names of this protein?
A-kinase anchor protein 7 isoforms delta and gamma, AKAP-7 isoforms delta and gamma, A-kinase anchor protein 18, AKAP-18, Protein kinase A-anchoring protein 7 isoforms delta and gamma, PRKA7 isoforms delta and gamma.
What are the subcellular locations of this protein?
[Isoform Gamma]: Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Isoform Delta]: Nucleus. Cell membrane. Note=Cotranslocates with AQP2 to the plasma membrane in response to arginine-vasopressin (AVP) stimulation in inner medullary collecting duct (IMCD) cells.
Protein: RS3_STRTD
Sequence: MGQKVHPIGLRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFIQKELADASVSTIEIVRAVNKVIVSLHTAKPGMVIGKGGSNVDALRAQLNKLTGKQVHINIVEIKKPDLDAHLVGETIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEAHTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MTNA_ORYSI
Sequence: MGELGALQSIVYHRGSLRLLDQRKLPLEVDYIDVKCSGDGWNAIRDMVVRGAPAIAIAAALALAVEVSGLEDFTGTPAEAAAFVSEKLEYLVSSRPTAVNLSDAATKLRSLVSRTAETEKDAKAIFQAYIDAAETMLVDDVSDNKAIGSHGAEFLKQKLEVSKDISVLTHCNTGSLATAGYGTALGVIRALHSGGILEKAFCTETRPFNQGSRLTAFELVHDKVPATLIADSAAAALMKSGCIQAVIVGADRIAANGDTANKIGTYNLAISAKHHGVQFYVAAPITSIDLSLPSGEQIVIEERSPNELLNSEGGLGKQVAASGISVWNPAFDVTPANLITAIITEKGVITKSDADETFNIKDFIQSAKLYSTMQ
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SRY_BISBO
Sequence: MFRVLNDDVYSPAVVQQQTTLAFRKDSSLCTDSHSANDQCERGEHVRESSQDHVKRPMNAFIVWSRERRRKVALENPKMKNSDISKQLGYEWKRLTDAEKRPFFEEAQRLLAIHRDKYPGYKYRPRRRAKRPQKSLPADSSILCNPMHVETLHPFTYRDGCAKTTYSQMESQLSRSQSVIITNSLLQKEHHSSWTSLGHNKVTLATRISADFPFNKSLEPGLSCAYFQY
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: HSLU_THISH
Sequence: MSDMTPREIVQELDKHIVGQKDAKRAVAIALRNRWRRQQLPEALRQEVTPKNILMIGPTGVGKTEIARRLARLANAPFIKVEATKFTEVGYVGRDVESIIRDLVDAAIKLLREQEMGKVRFRAEEAAEERVLDVLLPAPRQAGFMSEPASAPEQSETRQKFRKRLREGQLDDKEIEIQVSATPVGVEIMTPPGMEEMASQLQSLFQNIGGGRSQTRKLKIRDAMKLLTDEEAARMVNQDELKLRAVANVEQNGIVFLDEIDKVAKRGEYGGADVSREGVQRDLLPLVEGCTVNTKFGMVRTDHILFIASGAFHLSKPSDLIPELQGRLPIRVELSALTAEDFVRILTEPDASLTEQYSALLQTEGVEVNFAEDGVRRIAEIATRVNERTENIGARRLHTVMERLLEQISFEAPDHQGPVSIDAAYVDERLEELVQDEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_MYCS5
Sequence: MAYNKRKKGYHNKKRTCHFCDNKLTYVDYKNVEDLKKFVNAVGSIKPKVATGNCAKHQRKVTLAVKRARLMALLPFAVARIRVHRSLVSAPASQNTKKVAEKVEKEKAPAA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: UNG_PSEPG
Sequence: MTDDDRIKLEPSWKAALRGEFDQPYMHQLREFLRGEYAAGKEIYPPGPLIFNALNSTPLDQVKVVILGQDPYHGPGQAHGLCFSVQPGVATPPSLVNIYKELQRDLNIPIASHGYLQSWAEQGVLLLNTTMTVERANAASHAKKGWEFFTDRVIQVVSEQCPNVVFLLWGAHAQSKQKLIDGTKHLVLKSVHPSPLSAYRGFLGCGHFSRTNSFLEQRGMAPINWALPPL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_NEIMA
Sequence: MPQNTLNIVILAAGKGTRMYSKMPKVLHEIGGETMLGRVIDTAAALNPQNICVVVGHGKEQVLDTVKRDVVWVEQTEQLGTGHAVKTALPHLAAEGRTLVLYGDVPLIDVETLETLLEAAGNEVGLLTDVPADPSGLGRIIRDSSGSVTAIVEEKDADAAQKAVKEINTGILVLPNAKLEAWLNSLSSNNAQGEYYLTDLIAKAVADGIKIHPVQVRSSHLAAGVNNKLQLAELERIFQTEQAQELLKAGVTLRDPARFDLRGRLKHGQDVVIDVNCIFEGKIELGDNVEIGANCVIKNAKIGANSKIAPFSHLEGCEVGENNQIGPYARLRPQAKLADDVHVGNFVEIKNAAIGKGTKANHLTYIGDAEVGSKTNFGAGTIIANYDGVHKHKTVIGDEVRIGSNCVLVSPVKIGNKVTTGAGSTITRNVEDGKLALARSRQTIIDGWVRPEKNKQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_ARITO
Sequence: MEELRGYLEKSRSIQQHFLYPLLFQEYIYALAHNHGLNVNGSIFYEPPEISGYDKKFSSLLVKRLITRMYQQNYLINSFNDSNQNGFVGHNKNFYSQMISEGFAVIVEIPFSLRLVSSLEEKKEIPKSQNLRSIHSIFPFFEDKLSHLNCISDILIPYPVHLEILVQIIQCWIQDVPSLHLLRFFFHEFYNWNNLITPKKSNYYGFSKENPRLFLFLYNSYVVECESILVFLRKQSSYLRSTSSGTFLERTHFYEKIEQHLVVLCCNDFKKTLWLFKDPFIHYVRYQGKSILASKGTHLLMKKWKSYFVNFWQCHFHFWSQPSRIHISQFSNFSFYFLGYLSSVPLNPLAVKSQMLESSFLIDTVTKKCETIVPIIPMIGSLSKAKFCNVSGNPISKPVWADLSDSDIIDRFGRICRNLSHYYSGSSKKQSLYRIKYILRLSCARTVARKHKSTVRAFLQRLGSEFLEEFFMEEEKVLSLILPRISYPLHKLYRERIWYLDIIRINDLANHL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MSCL_SHESW
Sequence: MSLIKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADVIMPPIGIILGGVNFSDLSIVLQAAQGDAPSVVIAYGKFIQTVIDFTIIAFAIFMGLKAINTLKRKEEEAPKAPPTPTKEEELLSEIRDLLKAQQEK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL4P_YEAST
Sequence: MTIKRNLVKTLQSIRYQATTATAHAESTLNPLPNAAIPPKYALVTVRSFPSLEPLTFVPVPTSTVAAPLRRDILWRAVVYENDNRRVGASNPPGRSENGFSRRKLMPQKGSGRARVGDANSPTRHNGGRALARTAPNDYTTELPSKVYSMAFNNALSHQYKSGKLFVIGGEKVDLISPTPELDLNRLDLVNTNTVEGKEIFEGEVIFRKFLEEFQLKGKRLLFITDKTREGLIKSSDPYKQKVDVIQKELVEVNDILRAQAVFIELEALEYLAMAHQKEILHSVSN
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein YmL6, mitochondrial, Mitochondrial large ribosomal subunit protein uL4m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: ENO_HELHP
Sequence: MVYIEAIDAQEVMDSRGNPTVRAAVRLSDGTRAAAIVPSGASTGKREALELRDGDKERYLGKGVLKACANIKTEIAAQLDGVSPYDQSKIDLILKKIDGTENYSELGANATLGVSMAIARASAQSLRLPLYRYLGGSNALTLPTPMLNIINGGSHADNTVDFQEYMIMPLGFDTFAESLRASAEIYHHLKAILKGSGHITSIGDEGGFAPNLKNNEEPIEIILKAIEQAGYKPLDEIAIALDVASSELVDENGMYHLAGEGKVLDSAGMIAYYENLVAKYPIVSIEDGLSEDDWEGWKLLTQKLGNKIQLVGDDLFVTNKKILQEGIEKNIANAILIKPNQIGSVSETMQSVRLAQRNNYKCIMSHRSGESEDTFIADFAVALNTGEIKTGSTARSERIAKYNRLLEIEREISDAEYIGKTLFKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.