PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_RHOPT
Sequence: MTDPSRLVTPERRGDDLGDAALRPQNLSEFVGQQQARANLQVFIDAARKRKEALDHVLFVGPPGLGKTTLAQIVARELGVGFRATSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPSVEEVLYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVGATTRAGLLTNPLRDRFGIPIRLNFYTIEELESIVTRGARVLGTPITADGANEIARRARGTPRIAGRLLRRVRDFASAADAEAIDRSIADHALGALEVDSAGLDAMDRRYLTTIALNYGGGPVGVETMAAALSEPRDAIEDIIEPYLIQCGYLQRTPRGRLLTDHAFRHLGLAAPSRDPAQFGLFGDTGDQE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GYRB_CYTHU
Sequence: DKDSYKVSGGLHGVGVSCVNALSTDMKVTVYSHGKVHQQEYKKGIPQYDVKEIGESDLHGTKVQFLPDDTIFTSSEYKYETIANRLRELSFLNKGIRITLQDHRQVDAEGKSEIEMFHSEGGLREFVDYLDSTREKLIPTPLYMESDKGPIPVEVAMLYNTSYSENVFSYVNNINTIEGGTHVAGFRRALTRTLKSYADKSGMLEKLKMEVTGDDFREGLTAVISVKVQEPQFEGQTKTKLGNSDVMGAVDQVVGEMLNTYLEENPKEAKIIVQKVILAAQARNAARKAREMVQRKNVLSGSGLPGKLADCSESDPEKCELYLVEGDSAGGSAKQGRDRKYHAILPLRGKILNVEKAQEHRIYENDEIKNMITALGVSFGTEEGEKVLNLTKLRYHKVIIMTDADIDGSHIRTLILTFFFRYMRALIDGGHVYIAQPPLYLVKRGKEEKYCWTEEQREAAVKELAKDGKEDSVGIQRY
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1021_STRPQ
Sequence: MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHAARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKFNTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYASPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMNDIGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSGLFGPTAAVIINAIKTLAKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKELGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK
What are the official names of this protein?
UPF0371 protein SPs0839.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: RS14_PROMA
Sequence: MAKKSMIARDVKRKKLVERYASKRKKLLDQFHSAKDPMERLEIHRKIQALPRNSAPSRMRNRCWATGKPRGVYRDFGLCRNQLRERAHKGELPGVVKSS
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: CLPP_ALCBS
Sequence: MSQLIKDPTNLGLVPVVIEQTARGERSFDIYSRLLKERVIFMIGQVEDHMANLIVAQMLFLESENPDKDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTMCIGQAASMGAFLLTAGAAGKRFALPNARVMIHQPLGGFQGQASDIEIHAKEILKIKGQLNSLLAHHTGQPIEQLEKDTDRDNFMSADEAKEYGIIDAVLSQRPV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFHI_BACSU
Sequence: MSIKNPSVKFIIFVLMICTFSIGYTEYAVMGILTSIANDFHIQVSSAGLLVTAYAASVCLTGPLVTIISVKLPRKPVLLGLMAIFILSNLMSALAPNFAVLAISRILSASIHGAFFAIAMVFASEMVPPEKRAAAAASMNGGLTVALMLGVPFGSYLGDVLNWRAVFSIITALGVIGFLGLMAAVPNRKPKVIPMLMNEWGVFKHKQVLFSFAITILGYSGVFIAYTFIEPILRHSAGFSTVGITGALFAYGLGGVAGNFFAGKVPLPLLTRTMIGVMIGLIGVLAVFPYIAIYPAAAIVATFLFGACAFGTPPLLQTKVISSSEGGTTIAAAVSVSAFNLANALGAWIGGMILNGTGSYSWLFAGGALMTACGLVLSTFAHLSEKKSVYEYQVNKG
What are the official names of this protein?
Uncharacterized MFS-type transporter YfhI.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPDA_DROKA
Sequence: MAEKVNVCIVGSGNWGSAIAKIVGANAAALPEFEERVTMFVYEEMIDGKKLTEIINETHENVKYLKGHKLPTNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYGKVLRDLFQANHFRVVVVEDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGSKLSTFFESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLFTAIHKICINQLKPKDLIDCIRNHPEHMDTFIMPSPKL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic, GPD-C, GPDH-C.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB5_CANTR
Sequence: MTDTDTTTTIYTHEEVAQHTTHDDLWVILNGKVYNISNYIDEHPGGEEVILDCAGTDATEAFDDIGHSDEAHEILEKLYIGNLKGAKIVEAKHAQSFSTEEDSGINFPLIAVGVFLAAFGVYYYKTNFA
What is the function of this protein?
Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
What are the official names of this protein?
Cytochrome b5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: UBIG_BURCM
Sequence: MTNADPHELQKFSDLAHRWWDPNAEFKPLHELNPVRLGWIDAHAHLAGKRALDIGCGGGILSESMAGLGAQVKGIDLSTEALGVADLHSLESGVTVDYEAIAAEALAEREPGTYDVVTCMEMLEHVPSPAGIVSACATLVKPGGWVFFSTLNRNLKSYLFAVIGAEYIARMLPKGTHDYARFIRPSELASFVRGTDLHIVEIKGITYHPIGKRFALSNDTDINYLVACRRGA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: LRE_ARATH
Sequence: MELILLFFFLMALLVSLSSSSSISDGVFESQTSVSGRNLRHAKKKCEVNFEYMDYKVLTKRCKGPAFPAKECCSAFKEFACPYVSQINDMNSDCAQTMFSYMNIYGNYPTGLFANECRERKDGLVCPLPPLYSHNLNASTADSTPRFISLLISAATAVFALLVLT
What is the function of this protein?
Female gametophyte-specific component of the signaling pathway required for fertilization.  Required for reception of the pollen tube by the female gametophyte (PubMed:19028964, PubMed:26052747, PubMed:27081182).  Acts specifically at the synergid cell surface for pollen tube reception (PubMed:26052747, PubMed:27081182).  Plays a role in double fertilization and early seed development (PubMed:20163554).  Component of the FER-regulated Rho GTPase signaling complex.  Acts as a chaperone and coreceptor for FER.  Required for localization of FER to the plasma membrane (PubMed:26052747).
What are the official names of this protein?
GPI-anchored protein LORELEI.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=Localized to the filiform apparatus of the synergid cell.
Protein: ANS1_ORYSJ
Sequence: MTDVELRVEALSLSGVSAIPPEYVRPEEERADLGDALELARAASDDDATARIPVVDISAFDNDGDGRHACVEAVRAAAEEWGVIHIAGHGLPGDVLGRLRAAGEAFFALPIAEKEAYANDPAAGRLQGYGSKLAANASGKREWEDYLFHLVHPDHLADHSLWPANPPEYVPVSRDFGGRVRTLASKLLAILSLGLGLPEETLERRLRGHELAGVDDDLLLQLKINYYPRCPRPDLAVGVEAHTDVSALSFILHNGVPGLQVHHAGSWVTARPEPGTIVVHVGDALEILTNGRYTSVLHRGLVSRDAVRLSWVVFCEPPPESVLLQPVPELLADGADKPLFAPRTFKQHVQRKLFEKLKDQQDNNAAAASNGMRTK
What is the function of this protein?
Involved in anthocyanin and protoanthocyanidin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins.
What are the official names of this protein?
Leucoanthocyanidin dioxygenase 1, LDOX1, Leucocyanidin oxygenase 1, Anthocyanidin synthase, OsANS, Anthocyanidin synthase 1, OsANS1, Leucoanthocyanidin hydroxylase 1.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: UREE_RUEPO
Sequence: MDLPACRDIRRTGHWSEADDRVTLSYDDRFLRRKRLITVQDKAFLVDLAHTTSLEHGDAFQLEDGRLIECIAADEDLLEVTGPDLTRLAWHIGNRHTPCQIEENRLLIQRDHVIQDMLSQIGATLREVVEPFTPEGGAYGHGRTHGHAH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U4_FBNY2
Sequence: MECRFFISIILFVVLLNPSLIINMVLGYVLGSLFRSNYSRLKKLLSGNKNENREEEDEHISQMKNPFEDAESDVLQHLKTLGLETKVEGDDLEYLQRLWESMSSKK
What are the official names of this protein?
Protein U4.
What is the protein family that this protein belongs to?
Belongs to the nanovirus U4 protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS15_GLAP5
Sequence: MSLSVEAKAKIVAEFGRDAKDTGSSEVQIALLTAQINHLQAHFAEHKKDHHGRRGLLRMVSRRRKLLDYLKRTDLAKYSETIARLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DUT_RALSO
Sequence: MKLDVQILDARLHEQLPQYATPGSAGLDLRACLDAPLTLEPGSTHLIPTGMAIHLADPGYAALILPRSGMGHKHGIVLGNLVGLIDSDYQGQLMISTWNRGDTAFVLNPMERLAQLVIVPVVQAELNIVDAFAESERGAGGFGSTGRH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL21_CORJK
Sequence: MYAIVKTGGKQYKVAEGDLVKVEKIEGEPGSSVALTPVLVVDGANVTTGDKLASVNVNAEIVEHVRGPKIRGMHYRNKTGYKRRFGHRQSLTVLKVTGIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CD2B2_DROME
Sequence: MASKRKHQASQKVKEESFKKHTLDSDEEDSDDYEREYLNDSDIEGGEEGVAKVEDDVKVTPFNMKEELEEGHFDKDGHYHWNKETEAKDNWLDNIDWVKIGTQKNAFDPAKDEENSSDEEKNEPVGKAFNLSMNLMKMVEFMKPGETVKMTLQRLGKQRPVLTTLQRIKQKKAGIVDPKTQEISQLTELANEILSKTGNMDIYQDTYESIKAKIADLPGTSKPKVADDIDMYADDFETKELERSKTSSSDSSKPTTTTSEVTWEFKWSQDETDIQGPFSTEKMLKWSQENYFKNGVYVRKCGENTNFYTSNRIDFDLYL
What is the function of this protein?
Required for embryonic epithelial tissue repair, but not for the assembly of the actomyosin cable at the wound edge.  Probably acts downstream of rl in the regulation of Ddc and msn transcription to promote wound healing.
What are the official names of this protein?
CD2 antigen cytoplasmic tail-binding protein 2 homolog, Protein hole-in-one.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYDND_BRASB
Sequence: MHRYRTHTCGALRDSNIGETVRLSGWCHRIRDHGGVLFVDLRDHYGITQCVVDPDSKAFGLAEKLRSEWVVRMEGKVRRRPEGTDNAELPTGQVELYVADIEVLGPAAELPLPVFGEQEYPEDIRLKYRFLDLRREKLHQNIMTRGAIIDSMRRRMKEQGFFEFQTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDVEMSFVEQEDVFAAMEPVITGVFEDFAKGKPVTKGWPRIPFAEALRKYGTDKPDLRNPIEMQDVSEHFRGSGFKVFARMLEDTKNQVWAIPAPGGGSRAFCDRMNSWAQGEGQPGLGYIMWREGGEGAGPLANNIGPERTAAIRTQLGTKEGDAAFFVAGDPEKFWKFAGLARTKVGEELNLIDKDRFALAWIVDFPMYEYNEDDKKVDFSHNPFSMPQGGLEALQTKDPLTIKAFQYDIACNGYEIASGGIRNHKPEAMVKAFEIAGYGEQEVVDRFGGMYRAFQYGAPPHGGMAAGVDRIVMLLCGTTNLREISLFPMNQQAMDLLMGAPSEATTKQLRELHIRTNLPNK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_GLOMM
Sequence: MSKIGINGFGRIGRLVLRAALDKGAEVVAVNDPFIDVNYMVYLFKYDSTHGRFKGTVAADGGFLVVNGKKITVFCERDPTNINWASAGAEYIVESTGVFTTIDKASAHFKGGAKKVVISAPSADAPMFVCGVNLEAYSPDMKVVSNASCTTNCLAPLAKVIHDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTVRLGKSATYDEIKAKVLEASQGPMKGILDYTEEEVVSTDFVGDTHSSVFDAKAGIPLNDKFVKLISWYDNEFGYSNRVIDLIKYMQSKDA
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_UREPA
Sequence: MSKELKLFRNFGIMAHIDAGKTTTSERILYHTGKNHKIGETHDGAATMDWMAQEKERGITITSAATYAKWKGHSLNLIDTPGHVDFTVEVERSLRVLDGAVAVLDGQNGVEPQTETVWRQATKYNVPRIVFVNKMDKTGADFYYSIETMKNRLGVKATAIQIPIGAEADFVGSIDLIEMKAYIYDGKADEEYKIEDIPADYLTKAQVMRSQMIDDVAVFDDEVMEKYLSGEELSHEDIKKCIRKGVISTELYPVLCGTAFKNKGVKKLLDAVVDFLPSPIDVPPIKGVDDHGNPIEYHNDPNEPFAALAFKVATDPFVGRLTYIRVYSGKLDKGTYIYNATKDKKERISRLVKMHSNNRDEIDSISAGDICAVIGLKDTTTGDTICDEKKPVILEQMVFAEPVISLSVEPKTKADQEKMSLALSKLAEEDPTFRTYTNEETGQTIIAGMGELHLDVLVDRMRREFNVQVNVGAPQVSYRETFTEVADAEGKYIKQSGGRGQYGHVWIKFEPNHDKGFEFVDNIVGGKVPKEYIKEVENGLIEALTSGPIAGYQTIDVKATIFDGSYHDVDSSGMAYKIAASLAFKEAAKVCKPVLLEPIMSVDVTTPDDYFGTVMGDISKRRGVIEGQEQRGNAQAIKAKVPLSEMFGYATDLRSNTQGRGQYIMQFSHYAQAPKSVTEEVMVARAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYM2_FLAPR
Sequence: MAMASALRRLSSSSNKPLQRLFNGGHLYSMSSLPSEAVYEKERPGVTWPKQLNAPLEVGDPEIADIIELEKARQWKGLELILSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFRLDAAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYDYARIRKVCDKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFRKGVKEVNKQGKEVLYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTAEYKAYQEQVMSNCAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYLFDLAVKLAVKIKGEAQGTKLKDFVAAMQSSAFQSEISKLRHDVEEYAKQFPTIGFEKETMKYKN
What is the function of this protein?
Catalyzes the interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase 2, mitochondrial, SHMT2, Glycine hydroxymethyltransferase 2, Serine methylase 2.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PTHD1_HUMAN
Sequence: MLRQVLHRGLRTCFSRLGHFIASHPVFFASAPVLISILLGASFSRYQVEESVEHLLAPQHSLAKIERNLVNSLFPVNRSKHRLYSDLQTPGRYGRVIVTSFQKANMLDQHHTDLILKLHAAVTKIQVPRPGFNYTFAHICILNNDKTCIVDDIVHVLEELKNARATNRTNFAITYPITHLKDGRAVYNGHQLGGVTVHSKDRVKSAEAIQLTYYLQSINSLNDMVAERWESSFCDTVRLFQKSNSKVKMYPYTSSSLREDFQKTSRVSERYLVTSLILVVTMAILCCSMQDCVRSKPWLGLLGLVTISLATLTAAGIINLTGGKYNSTFLGVPFVMLGHGLYGTFEMLSSWRKTREDQHVKERTAAVYADSMLSFSLTTAMYLVTFGIGASPFTNIEAARIFCCNSCIAIFFNYLYVLSFYGSSLVFTGYIENNYQHSIFCRKVPKPEALQEKPAWYRFLLTARFSEDTAEGEEANTYESHLLVCFLKRYYCDWITNTYVKPFVVLFYLIYISFALMGYLQVSEGSDLSNIVATATQTIEYTTAQQKYFSNYSPVIGFYIYESIEYWNTSVQEDVLEYTKGFVRISWFESYLNYLRKLNVSTGLPKKNFTDMLRNSFLKAPQFSHFQEDIIFSKKYNDEVDVVASRMFLVAKTMETNREELYDLLETLRRLSVTSKVKFIVFNPSFVYMDRYASSLGAPLHNSCISALFLLFFSAFLVADSLINVWITLTVVSVEFGVIGFMTLWKVELDCISVLCLIYGINYTIDNCAPMLSTFVLGKDFTRTKWVKNALEVHGVAILQSYLCYIVGLIPLAAVPSNLTCTLFRCLFLIAFVTFFHCFAILPVILTFLPPSKKKRKEKKNPENREEIECVEMVDIDSTRVVDQITTV
What is the function of this protein?
Required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, generation of sleep rhythms, sensorimotor processing and attention.
What are the official names of this protein?
Patched domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL15_MALP2
Sequence: MKLENLKSKEGSRHKTKRVGRGFGSGIGKTSTRGSKGQKSRKSGHTRPGFEGGQTTLYRRIPKIGFNNKNFANNYNVVTLNNIVKLNLANVDKKVLVEKGLIEDNKLPIKVIGTATISKPISVSAHKFSKGSVATLEKSKSKFVVIK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ISCS_RICAH
Sequence: MNQQLNNLTLPIYMDYQATTPLDPRVMEAMLPYFTTKFGNPHSRSHSFGWEAERAVEEARSRVARLIGADTKEIIFTSGATESNNLAIKGVAKFYGNKKNHIITVVSEHKCVLDACRYLEQEGINITYLPVKPNGIIALETLKNAITDQTMLVSVMAVNNEIGVVQPLKEIGKICRARGVFFHSDIAQGFGKIPIDVNEFNIDLASISGHKIYGPKGIGGLYVRKKPRVRVTPLINGGGQERGMRSGTLPTPLIVGLGVAAEIAYSEMEKDTKHVNYLFDRFLNNIHSRISEVYLNGAKDPRYKGNLNLSFAGVEGESIILAIKDLAVSSGSACTSASLEPSYVLRSMGIGEELAHTSIRFGIGRFTTEQEIDYAVNLICSKIDKLRKLSPLWEMMQEGIDLKKIKWAVH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLB_BUSCA
Sequence: GLDGAQKTALKESWKVLGADGPTMMKNGSLLFGLLFKTYPDTKKHFKHFDDATFAAMDTTGVGKAHGVAVFSGLGSMICSIDDDDCVBGLAKKLSRNHLARGVSAADFKLLEAVFKZFLDEATQRKATDAQKDADGALLTMLIKAHV
What are the official names of this protein?
Globin, Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_SHIB3
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP157_ARATH
Sequence: MAALIQTIHGGVVVTRTLTLVYPSTFTSRHKALNQMTSSSNSGLRRFLFTPPQRLSQGICYWGAELSNNVSWTYKTKMVVRSKAGAVPLMKHGDRFLSSLSSPALAGDPSAINRHIKKFVAASPKSVALNVLSHLLSDQTSHPHLSFFALSLYSEITEASWFDWNPKLIAELIALLNKQERFDESETLLSTAVSRLKSNERDFTLFLCNLVESNSKQGSIQGFSEASFRLREIIQRSSSVYVKTQAYKSMVSGLCNMDQPHDAERVIEEMRMEKIKPGLFEYKSVLYGYGRLGLFDDMNRVVHRMGTEGHKIDTVCSNMVLSSYGAHDALPQMGSWLQKLKGFNVPFSIRTYNSVLNSCPTIISMLKDLDSCPVSLSELRTFLNEDEALLVHELTQSSVLDEAIEWNAVEGKLDLHGMHLSSSYLILLQWMDETRLRFSEEKCVIPAEIVVVSGSGKHSNVRGESPVKALVKKIMVRTGSPMRIDRKNVGSFIAKGKTVKEWLCK
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g17033.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: NU3M_PERSJ
Sequence: MNMLTALLVNITLSMLLIIVAFWFFQLNLYTEKANPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQMYNTNIMMLTAFILISVLALGLAYEWLQKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNAA_FRATN
Sequence: MTTWDKCLKKIKKNLSTFEYKTWIKPIHVEQNSNLFTVYCNNEYFKKHIKSKYGNLILSTIQECHGNDLIIEYSNKKFSGKKITEVITAGPQANFFSTTSVEIKDESEDTKVVQEPKISKKSNTKDFSSSQELFGFDEAMLITAKEDEEYSFGLPLKEKYVFDSFVVGDANKIARAAAMQVSINPGKLHNPLFIYGGSGLGKTHLMQAIGNHAREVNPNAKIIYTNSEQFIKDYVNSIRLQDQDEFQRVYRSADILLIDDIQFIAGKEGTAQEFFHTFNALYENGKQIILTSDKYPNEIEGLEERLVSRFGYGLTVSVDMPDLETRIAILLKKAHDLGQKLPNETAAFIAENVRTNVRELEGALNRVLTTSKFNHKDPTIEVAQACLRDVIKIQEKKVKIDNIQKVVADFYRIRVKDLTSNQRSRNIARPRQIAMSLARELTSHSLPEIGNAFGGRDHTTVMHAVKAITKLRQSNTSISDDYELLLDKISR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.