PharMolix/UniProtQA huggingface dataset:
Protein: AIDA_MOUSE
Sequence: MSEVTRSLLQRWGASLRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPIPLRRILAPGEEENLEFEEDEEGGAGAGPPDSFSARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVERLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQSLHKE
What is the function of this protein?
Acts as a ventralizing factor during embryogenesis (By similarity).  Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization.  This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
What are the official names of this protein?
Axin interactor, dorsalization-associated protein, Axin interaction partner and dorsalization antagonist.
What is the protein family that this protein belongs to?
Belongs to the AIDA family.
Protein: ILVC_ECO57
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVHTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDLNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: UVRC_NITOC
Sequence: MANFDIDDFLRNLTPCPGVYRMLDAKGKVLYVGKAKNLKRRIKSYFRNSKLAPKIHVLVKQICDIKITVTHTENEALILESNLIKALQPRYNVLLRDDKSYPYIFLSADDFPRLGFHRGVKQVSGQYFGPYPNIRSVWQTLKLLQRVFPVRQCEDNFYRNRSRPCLQYQIKRCTAPCVGLISKKDYSQDIQHVVMFLKGRDQQVINELVIRMEEASGQLAFEQAAYYRDRIASLRQIQARQYISGEKKDIDVLGVALTEKMACVEVFFIRGGHNLGNKTFLPKLEGNLTPEELLSTFIAQYYLNRETPPILILSHQPKDMGLLTEVLSKQAGRKIALIKPVRGPKVQWIKMALANAKINLNQHLAEKSNITARFKSLQQLLSLANFPQRIECFDVSHIQGTATVASCVVFDREGPRKADYRRFNITGIIPGDDYGALRQALMRRFKKKEGVFPDLLVIDGGKGQINQSLRVLKEIGITEITVLGIAKGPERKAGNETLFLAGYENPVMVTSDSPALHILQHIRDEAHRFAIVSHRKRRAKGGKLSLLEGISGLGPKRRRKLLIQLGGLQEITRAGVEDLAQIEGISLELAQRIYDVFHR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KKX25_OPICY
Sequence: MESSRKSYVLMLFLAFVIMNVCSVSGEPKDGEIAGFEMEEARYDACVNACLEHHPNVRECEEACKNPVPP
What is the function of this protein?
Voltage-independently blocks potassium currents on hKv1. 1/KCNA1 (IC(50)=217 uM), and hKv1. 4/KCNA4 (IC(50)=71 uM) (expressed in CHO cells).
What are the official names of this protein?
Potassium channel toxin kappa-KTx 2.5, OcyC8, OcyKTx6.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor kappa-KTx family. Kappa-KTx 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OXND1_PONAB
Sequence: MACAAVMIPGLLRCSVGAICTEAASLRLTLSTLRHLTLTSIMKSKRKTDHMERTASVLRREIVSAAKVCGAASESPSVKSLRLLVADQDFSFKAGQWVDFFIPGVSVVGGFSICSSPRLLEQERVIELAVKYTNHPPALWVHNTCTLDSEVAVRVGGEFFFDPQPADASRNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKSTSELLFKKNILDLVNEFPEKIACSSHVTKQTTQINAELKPYITGRITEKEIRDHISKETLFYICGPPPMTDFFSKQLENNHVPKEHICFEKWW
What are the official names of this protein?
Oxidoreductase NAD-binding domain-containing protein 1.
Protein: RSGA_VARPS
Sequence: MAKPGRTPAKGAGTSARILHDGLVIASHGRHCLVETPTGERLICHPRGKKSQAVVGDRVRWQASEDEGTIEEVVPRRNLFYRQDEIRTKSFAANLDHVLILIAAEPEFSEHQLARALIAAEAERITPIIALNKSDLAEPFERAWNKLAPYRRMHHGVLPLSLKASGEADYASLMKLLAGKSTLVLGPSGAGKSTLINLLVPGATALTGEISQALNSGKHTTTSTTWYWVDEARTTSLIDSPGFQEFGLNHIAPMQLAGLMPDIAEHANDCKFYNCTHLHEPGCGVIANVDAPGKPGPISATRYRIYGELFAELSQSRY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTF3_HUMAN
Sequence: MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFG_STRA1
Sequence: MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDAQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQSLHDRLQANAHPIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYVDQANEYREKLVEAVADTDEDLMMKYLEGEEITNEELMAAIRKATINVEFYPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGINPDTDEEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKSKVILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVISGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEARGNTQVVRAFVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNSGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPB_ECOSE
Sequence: MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: PSBI_TRIEI
Sequence: MLTLKIVVNIVVLFFVLLFIFGFLSNDPARNPSGRDME
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RECF_COXBU
Sequence: MPYIGSLKVNQFRNLADVDITPHSQFNFFFGQNGAGKTSILESIYYLSVGRSFRTHLPQRLIQDNTDRFLIFITLYNGTQFIPLGVERDCHGDRCLRINGETASSWSLAAKRLPLCSLSAMSHRFLLDGPRVRRQFLDWLMFHVEPSFFSIWQRLQRSLKQRNAALKAKLPLGEITHWDKMLVEDGERLHQLRQNVVTEFKPLFTQMLQQFLPAYPLIGHYFRGWSEKYSLMEQLQINLKQDLQRGYTQAGPQRADFRLTLGDLPAQDILSQGQQKLVTYALHFAQGLLLKEKTGISPIYLIDDLPAELDANKRDCVIDLVNCLESQVFISGIDPNEIRLPPHSTLFHVKHGKVAAL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_AFIC5
Sequence: MKFLDEAKVYIRSGDGGNGCVAFRREKFIEYGGPNGGNGGRGGDVIIETVDGLNTLIDYRYQQHFKAQKGGHGMGSDRHGAGGDDIVLKVPVGTQVFDEDRETLLHDFTRLGERFVIAKGGNGGFGNAHFKSSTNRAPRHANPGQPGEERWIWLRMKLIADAGLVGLPNAGKSTFLSVVSAAKPKIADYPFTTLHPQLGVVRSDGREFVLADIPGLIEGAHEGTGLGDRFLGHVERCRVLLHLVDATCEHAGKAYKIVRNELAAYEHDLTDKVEIVALNKIDAVTPEQLKEQKARLKRAAKQTPMLVSGVTGEGVPEVLRALTDVISEAPVSTKAKGEPTENETPPPSTGWSPLSN
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTA_HALED
Sequence: MNATTEPFTPSADLAKPSVADAVVGHEASPLFIRKPSPDDGWGIYELVKSCPPLDVNSAYAYLLLATQFRDSCAVATNEEGEIVGFVSGYVKSNAPDTYFLWQVAVGEKARGTGLARRLVEAVMTRPEMAEVHHLETTITPDNQASWGLFRRLADRWQAPLNSREYFSTDQLGGEHDPENLVRIGPFQTDQI
What is the function of this protein?
Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.  Does not acetylate amino acids like GABA, L-ornithine, L-lysine and L-aspartate.
What are the official names of this protein?
L-2,4-diaminobutyric acid acetyltransferase, DABA acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. EctA subfamily.
Protein: RECO_STRPM
Sequence: MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSKMSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAIADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDLPLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKLRQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: DEOD_STRGC
Sequence: MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEDVHVRELVLAQAAATNSNIIRNDWPQYDFPQIASFDLLDKAYHIAKDLGMTTHVGNVLSSDVFYSNYFEKNIELGKWGVKAVEMEAAALYYLAAQHHVDALAIMTISDSLVNPEEDTTAEERQNTFTDMMKVGLETLIAEA
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: CLPX_THEVB
Sequence: MAKYDTHLKCSFCGKSQEQVRKLIAGPGVYICDECVELCNEILDEELATVPNAAAPRRESTPSRSPRSTPRSRPLSQVPKPRQIKEFLDKHVVGQHEAKKILAVAVYNHYKRLSLLDSDQRGDDNVELQKSNILLIGPTGSGKTLSAQTLAKLLDVPFAVADATTLTEAGYVGEDVENILLRLLQNANMDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPYQDCIQIDTTNILFICGGAFVGLEKTIEQRVGKKAMGFVRDGEPLPKEKRSADILKQLEPHDLVKYGMIPEFIGRIPVVAVLEPLDVAALADILTQPQNALLKQYQKLMRMDSVELRFEPAAVEAIAQEAYRRKTGARALRAIVEEIMLDVMYELPSRKDLRECTITPEMVEKRSTAELLLHPSSLPTLSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CBPE_BOVIN
Sequence: MARRGGCALLVLCGSLAACAWLLGAEARGPGGPVAGARRRRRPQEDGISFEYHRYPELREALVSVWLQCAAVSRIYTVGRSFEGRELLVLELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVQLIHNTRIHIMPSLNPDGFEKAASQLGELKDWFVGRSNAQGIDLNRNFPDLDRIVYINEKEGGPNNHLLKNLKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSCPDDDIFQSLARAYSSFNPPMSDPDRPPCRKNDDDSSFVEGTTNGAAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKNYWEDNKNSLISYIQQIHRGVKGFVRDLQGNPIANATLSVEGIDHDVTSAKDGDYWRLLVPGNYKLTASAPGYLAIAKKVAVPYSPAVRVDFELESFSERKEEEKEELMEWWKMMSETLNF
What is the function of this protein?
Sorting receptor that directs prohormones to the regulated secretory pathway.  Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
What are the official names of this protein?
Carboxypeptidase E, CPE, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.
Protein: PCNA_METMP
Sequence: MFRATCNTRDFKKVINATSNLVDEICFEVDENGIKASAMDPSHVALVSMEMPKDVFEEYEGDIQDIGIDLEALKKIIARGRGDEKLILDLDVEKNKLNITFKSNVTRKFSIALYDVSSSNLKVPDIEYPNSVSIKAGAFVEALKDAELVNDHITLKIDENKFVIYSKGDLNQSETVFDNSIDDDDNALADFNMGEASRSTFNLAYLKDLTKSTAAEDLLKIYLGSDMPVKIEYEVSGSKLVFLLAPRIES
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: SOTI_DROMO
Sequence: MENRVADELIHLPLPEVQAVNVINVRHGDGDGDGENGWERHLDDEQMQAMRLENPQVAMLLDAPHEPPIELHHMLEPVNVPERPRKKRSFLTISKPFHVQPERCALISNGWRAVQCVQPEKRGECFANYLIKHMNSRNYPNGEGLPKRWGQY
What is the function of this protein?
Post-meiotically transcribed gene that has a role in late spermiogenesis; required for actin cone progression during spermatid individualization.
What are the official names of this protein?
Male-specific protein scotti.
What is the protein family that this protein belongs to?
Belongs to the male-specific scotti family.
Protein: EFG_FRATM
Sequence: MPRNTALEKYRNIGICAHVDAGKTTTTERILFYTGLSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWSGMDQQFEKHRINIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQANKYGVPRIVFVNKMDRSGADFERVCAQIKTRLKANVVPVQLNIGAEEDFKGVIDLIRMKAIMWNEEDMGLTYELVDIPADLQDRAEELRMEMIEAAAEASEELMEKYLEGGELSEDEIHQGLRARVLNNEIVLAFCGSAFKNKGVQAVLDGVVRYLPAPNQVPAIKCETEDGEPASRPSSDDAPFAALAFKLATDPFVGNLTFIRVYSGVLKSGDAVYNPVKGKKERVGRIVQMHANKRDEIKEVRAGDIAACIGLKDVTTGDTLCDQEDVVILEKMDFPEPVISVAVEPKSKADQEKMSIALGKLAAEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFKVEANVGNPQVAYRETIRSKVEQEAKFVRQSGGRGQYGHVFVRFEPLDEVDENGEAKVFKFVDEVVGGVVPKEYIGSVAKGIEEQLNNGVLAGYPMIGVKATLYDGSYHDVDSSEMAFKIAGSMALKEGAKKANACILEPIMKVEVVTPEDYLGDVMGDLNRRRGIIEGMDENPSGRVINALVPLAEMFGYATNVRSISQGRASFSMEFKKYAEVPNNIADEIIKSHNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBD34_SEDHY
Sequence: MNKVTDLRSAIELLKTIPGQLIETNXDV
What is the function of this protein?
Reversibly catalyzes the decarboxylation of 3,4-dihydroxybenzoate to catechol.  Inactive toward 4-hydroxybenzoate and other benzoate derivatives.
What are the official names of this protein?
3,4-dihydroxybenzoate decarboxylase.
Protein: RSAMH_SALTO
Sequence: MAPTPWISFTTDYGLADGFVAACHGVLARLTPTTRVIDVTHLVPPGDVRRGAAVLAQAVPYLPAAVHLAVVDPGVGTARRAIALAAGDGLLVGPDNGLLLDAAAALGGVRAAVELTNRDWLGADVSATFHGRDIFAPVAARLALGAPLADAGPAVEPSTLVRLPVPLVRPEADGFTAEVLTVDHFGNVQLAASGSLLEPLPRSLRVERQPAVRVHTFGDVAPGELLVHVDSTGQVAVAVNGGRAADLLGVTPGDRLRVTAG
What is the function of this protein?
Specifically hydrolyzes (R)-S-adenosyl-L-methionine ((R)-SAM), the inactive form of the ubiquitous cofactor SAM, into adenosine and L-methionine.  Is stereoselective as it cannot use the active form of SAM, (S)-S-adenosyl-L-methionine, as substrate.  Likely plays a role in preventing accumulation of (R)-S-adenosyl-L-methionine in cells; maintenance of (S)-S-denosyl-L-methionine homochirality is important for cellular health given that the (R)-form is largely inactive as a methyl donor and can function as an inhibitor of methyltransferases.
What are the official names of this protein?
(R)-S-adenosyl-L-methionine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the SAM hydrolase / SAM-dependent halogenase family.
Protein: RL36_LACDA
Sequence: MKVRPSVKPMCEHCKVIKRHGRVMVICPANPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL13A_SALTR
Sequence: LLGRLAAIVANEVLLGHKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVFDGVPPPYDKRKRMVVPAALKIVRLKPTRKFALLGRLAHEVGWKYQAITATLEEKRKEKAKIRYAKKKTVTKLSKLAEKNVESTISKYTAVLKQYGVLV
What are the official names of this protein?
60S ribosomal protein L13a, Transplantation antigen P198 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: SPA_STAA8
Sequence: MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNKEQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEILHLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFIGTTVFGGLSLALGAALLAGRRREL
What is the function of this protein?
Plays a role in the inhibition of the host innate and adaptive immune responses.  Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins (PubMed:2938951, PubMed:4163007, PubMed:10805799).  In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region.  In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production.  Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin.  Acts directly as a pro-inflammatory factor in the lung through its ability to bind and activate tumor necrosis factor alpha receptor 1/TNFRSF1A (By similarity).
What are the official names of this protein?
Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SpA.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin-binding protein SpA family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor; Extracellular side. Secreted. Note=Cell wall anchoring is confered by the LPXTG motif and following sequences (PubMed:1638631). Anchored by sortase A (PubMed:10427003). SpA from strains A676 and V-I is secreted whereas SpA from Cowan 1 and 8325-4 is mostly attached to the cell wall (Probable). Newly synthesized protein is deposited at 2-4 foci/cell and eventually is distributed in a ring around the cell (PubMed:17416657).
Protein: SECA_ECO24
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.