PharMolix/UniProtQA huggingface dataset:
Protein: PFKA_STRU0
Sequence: MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGVNHGYAGLVAGDIFPISSKGVGDKISRGGTFLYSARYPEFANLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFNIQQVVKTIDDDFKKQGKNHHIIVLAEGVMSGDQFAQELKAAGNTSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKQGKGGFAVGIHNEELVESPILGSAEEGALFSLGEDGKIIVNNPHRARLDFAKLNRSLSR
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_IDIPH
Sequence: MTNIRKSHPLLKIINKSFVDLPAPSNISSWWNFGSLLGICLMLQIMTGLFLAMHYTADTTTAFNSVTHICRDVNYGWMLRYLHANGASMFFICLYLHVGRGLYYGSYLYKETWNVGVLLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ASXL1_HUMAN
Sequence: MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPEDTADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLSNPRDSYRASSQANKQKKKTGVMLPRVVLTPLKVNGAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAIRGQAEVTQDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQRGPATRQRDGHFKKRSRPDLRTRARRNLYKKQESEQAGVAKDAKSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPEFPVESVASRIQAEPDNLARASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQLHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDPVNVTPSSTPESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIPIPSNDEVVKQPKPESREHIPSVEPQVGEEWEKAAPTPPALPGDLTAEEGLDPLDSLTSLWTVPSRGGSDSNGSYCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTREAAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSLLLASTEYQPRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPPAHDDSMSESPQVPLTKDQSHGSLRMGSLHGLGKNSGMVDGSSPSSLRALKEPLLPDSCETGTGLARIEATQAPGAPQKNCKAVPSFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPGKSPGDLTTSRTPRFSSPNVISFGPEQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPADPMPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKANAENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQLSIKQAFYGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR
What is the function of this protein?
Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG) (PubMed:16606617).  Acts as coactivator of RARA and RXRA through association with NCOA1 (PubMed:16606617).  Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity (By similarity).  Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) (PubMed:20436459).  Acts as a sensor of N(6)-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its ubiquitination and degradation by TRIP12, thereby inactivating the PR-DUB complex and regulating Polycomb silencing (PubMed:30982744).
What are the official names of this protein?
Polycomb group protein ASXL1, Additional sex combs-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the Asx family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSMD9_YEAST
Sequence: MEEEELSKLLANVKIDPSLTSRISQIDSFKLSELMVLKTDIETQLEAYFSVLEQQGIGMDSALVTPDGYPRSDVDVLQVTMIRKNVNMLKNDLNHLLQRSHVLLNQHFDNMNVKSNQDARRNNDDQAIQYTIPFAFISEVVPGSPSDKADIKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREGQILKTSLTPSRNWNGRGLLGCRIQEL
What is the function of this protein?
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).  During the base subcomplex assembly is part of a NAS2:RPT4:RPT5 module; NAS2 is released during the further base assembly process.
What are the official names of this protein?
Probable 26S proteasome regulatory subunit p27, Proteasome non-ATPase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit p27 family.
Protein: NCAP_BRSVR
Sequence: MALSKVKLNDTFNKDQLLSTSKYTIQRSTGDNIDIPNYDVQKHLNKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTLKILKDAGYQVRANGVDVITHRQDVNGKEMKFEVLTLVSLTSEVQGNIEIESRKSYKKMLKEMGEVAPEYRHDSPDCGMIVLCVAALVITKLAAGDRSGLTAVIRRANNVLRNEMKRYKGLIPKDIANSFYEVFEKYPHYIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGAGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTTEELEAIKNQLNPKDNDVEL
What is the function of this protein?
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases.  RNA replication depends on the availability of soluble nucleoprotein.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Together with the phosphoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway.  May also act as a modulator of the innate immune response by sequestration of host IFIH1/MDA5 and MAVS into IBs.
What are the official names of this protein?
Nucleoprotein, Protein N, Nucleocapsid protein.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Localizes in cytoplasmic inclusion bodies.
Protein: CSPLH_ORYSJ
Sequence: MSSSGPPAGDGRDDASGPGPAGAAAAADGSVPVSRSIVERWKMEPAAARARLLLRAVAWLFSLLALVVMASNKHGHGGAQDFDNYPEYTYCLGISIIAVLYTTAQVTRDVHRLSWGRDVIAGRKAAAVVDFAGDQVVAYLLMSALSAAAPVTDYMRQAADNLFTDSAAAAISMAFLAFLAAGLSALVSGYNLAMEVLV
What are the official names of this protein?
CASP-like protein 4B3, OsCASPL4B3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL2_TROW8
Sequence: MAVRKSNPLTPARRGMSFSDFAEITRATPHKSLLSKLSKTGGRNNHGRITARHIGGGHKRRYRLVDFRRSDKDGVKAKVAHIEYDPNRTARIALLHFLDGAKRYILAPSGLKQGDVVESGSSADIRPGNSLCIRDIPVGTILHAVELRPGQGAKLARSAGSSVRLSAKDGDFAILKLPSGEIRMVSLSCRATIGEVGNGQRLNVSLGKAGRSRWCGVRPSVRGVAMNPVDHPHGGGEGKTSGGRHPVSPWGRPEGKTRRANKPSDRFIIRRKSRKRR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y1113_GEMAT
Sequence: MDLFKMLGQFKDMQGRMQTMQEEMSQRTFSALAGGGLVTADVDGKMQLKRIKLDASVVNPGDIEMLEDLIVVAVAEAQKKAADAMQMELQKVTGGIDLPFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein GAU_1113.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TALB_ECOLI
Sequence: MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase B.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBT45_MOUSE
Sequence: MAATEAVHHIHLQNFSRSLLETLNGQRLGGHFCDVTVRIREASLRAHRCVLAAGSPFFQDKLLLGHSEIRVPPVVPAQTVRQLVEFLYSGSLVVAQGEALQVLTAASVLRIQTVIDECTQIIARARVPNTPAPAPLPPPVPPPLAPAQLRHRLRHLLAARPPGHPNAAHSRKQRQPARLQLPAPPAPIKAEGPDAEPALTAAPEDRGEEDDDEETDEETDAEEGEGGGGGPGEGQAPPAFPDCAGGFLTTAADSAREDPPASTGITDYGGAGRDFLRGTGVTEDVFPDSYVSAWHEESSGGPESCPVETSAPPDCALAGPRPTGVKTPGPPVALFPFHLGAPGPPAPTPPTPSGPAPAPPPTFYPTLQPDAAPSAQLGETQAVPAAPAAQATAISGTPVRAPGGQGAEQPAYECSHCRKTFSSRKNYTKHMFIHSGEKPHQCAVCWRSFSLRDYLLKHMVTHTGVRAFQCAVCAKRFTQKSSLNVHMRTHRPERAPCPACGKVFSHRALLERHLAAHPAP
What is the function of this protein?
May be involved in transcriptional regulation (Probable).  In the central nervous system, may play a role in glial cell differentiation (PubMed:21131782).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 45, Zinc finger protein 499.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APL_ARATH
Sequence: MFHAKKPSSMNGSYENRAMCVQGDSGLVLTTDPKPRLRWTVELHERFVDAVAQLGGPDKATPKTIMRVMGVKGLTLYHLKSHLQKFRLGKQPHKEYGDHSTKEGSRASAMDIQRNVASSSGMMSRNMNEMQMEVQRRLHEQLEVQRHLQLRIEAQGKYMQSILERACQTLAGENMAAATAAAAVGGGYKGNLGSSSLSAAVGPPPHPLSFPPFQDLNIYGNTTDQVLDHHNFHHQNIENHFTGNNAADTNIYLGKKRPNPNFGNDVRKGLLMWSDQDHDLSANQSIDDEHRIQIQMATHVSTDLDSLSEIYERKSGLSGDEGNNGGKLLERPSPRRSPLSPMMNPNGGLIQGRNSPFG
What is the function of this protein?
Transcription factor required for phloem identity.  Has a dual role both in promoting phloem differentiation and in repressing xylem differentiation during vascular development.  Regulates the expression of the transcription factor NAC045 (AC A4VCM0).  May activate the transcription of specific genes involved in phosphate uptake or assimilation (PubMed:15592750).  Promotes flowering through transcriptional activation of both FT and its transport machinery component, FTIP1 (PubMed:26239308).
What are the official names of this protein?
Myb family transcription factor APL, AtAPL, Protein ALTERED PHLOEM DEVELOPMENT, Protein FE, Protein PHOSPHATE STARVATION RESPONSE 2, AtPHR2, Protein PHR1-LIKE 14, Protein WOODY.
What is the protein family that this protein belongs to?
Belongs to the MYB-CC family.
Protein: IMA7_HUMAN
Sequence: METMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQQFIFQQPEAPMEGFQL
What is the function of this protein?
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1.  Binds specifically and directly to substrates containing either a simple or bipartite NLS motif.  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
What are the official names of this protein?
Importin subunit alpha-7, Karyopherin subunit alpha-6.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
Protein: GPR31_MOUSE
Sequence: MERTNCSAASTVVETAVGTMLTLECVLGLMGNAVALWTFFYRLKVWKPYAVYLFNLVVADLLLATSLPFFAAFYLKGKTWKLGHMPCQVLLFLLAFSRGVGVAFLTTVALDRYLRVVHPRLRVNLLSLRAAWGISSLIWLLMVVLTPQNLLTCRTTQNSTECPSFYPTGGAKAIATCQEVLFFLQVLLPFGLISFCNSGLIRTLQKRLRESDKQPRIRRARVLVAIVLLLFGLCFLPSVLTRVLVHIFQEFKSCSVQQAIVRASDIAGSLTCLHSTLSPAIYCFSNPAFTHSYRKVLKSLRGRRKAAESPSDNLRDSYS
What is the function of this protein?
Proton-sensing G protein-coupled receptor.
What are the official names of this protein?
12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor, 12-(S)-HETE receptor, 12-HETER, G-protein coupled receptor 31.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL9_FERNB
Sequence: MKVVLIQDVPKLGKKGEVINASDGYARNFLIPRGLAREATPEVLKQLEKEKEEEKKRLEALKRESENLLSELHKHVFKIKAKAGDGGKLFGSLTSANISDVISKTLSKEFDKKWIVLDNPIKALGTYDVTVKLPGGVSGKIKVEVLREE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ENO_ALIFM
Sequence: MSKIVKVLGREIIDSRGNPTVEAEVHLESGFVGMAAAPSGASTGSREALELRDGDKARFLGKGVLKAVAAVNGPIAEALIGKDAKNQAEIDQIMIDLDGTDNKANFGANAILAVSLANAKAAAAAKSMPLYAHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTLAMDCAASEFFDKEAGIYNMKGEGKTFTSEEFNHYLAELANQFPIVSIEDGLDESDWAGFKHQTELLGDKLQLVGDDLFVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPFNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ARGJ_ASPFN
Sequence: MASPAQPAATMAAFARMVKGQVRSYSAPVDMAIPASKRKFIPSSGSYPKGFVVSGTHVGVKASNTKFPDLALISSETPCSAAAVFTTNKFQAAPVQVSRDIIKTRQGQGIRSVVINSGCANAVTGKGGLEDAVSMGKKVDECDGLNEPSTLVMSTGVIGQRLPISKILKKVPVAHANLSSTHDAWLTTARAICTTDTFPKLLSRTFTLPSSPGRTYSLAGMTKGAGMIHPNMATLLGVLCTDAPIEPSALQSLLKHSVNRSFNSISVDGDTSTNDTIAILANGAAGGAPISSSSSDDYAAMQDILTSFAQSLSQLVVRDGEGATKFVTVRVQNSPDYESGRLIASTIARSPLVKTALYGKDANWGRILCAIGYTQGVAPGTVVPEHTSVSFKPVDGSPVLNLLVNGEPEQVDEERASVILQEEDLEIVVDLGGGEKGEQGLGGEEAVYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: POLK_MOUSE
Sequence: MDNTKEKDNFKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDKFAMELERNRNLNNTIVHVDMDAFYAAVEMRDNPELKDKPIAVGSMSMLATSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILAEYDPNFMAMSLDEAYLNITQHLQERQDWPEDKRRYFIKMGNYLKIDTPRQEANELTEYERSISPLLFEDSPPDLQPQGSPFQLNSEEQNNPQIAQNSVVFGTSAEEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPSRSAVMDFIKDLPIRKVSGIGKVTEKMLMALGIVTCTELYQQRALLSLLFSETSWHYFLHIALGLGSTDLARDGERKSMSVERTFSEISKTEEQYSLCQELCAELAHDLQKEGLKGRTVTIKLKNVNFEVKTRASTVPAAISTAEEIFAIAKELLRTEVNVGSPHPLRLRLMGVRMSTFSSEDDRKHQQRSIIGFLQAGNQALSSTGDSLDKTDKTELAKPLEMSHKKSFFDKKRSERISNCQDTSRCKTAGQQALQILEPSQALKKLSESFETSENSNDCQTFICPVCFREQEGVSLEAFNEHVDECLDGPSTSENSKISCYSHASSADIGQKEDVHPSIPLCEKRGHENGEITLVDGVDLTGTEDRSLKAARMDTLENNRSKEECPDIPDKSCPISLENETISTLSRQDSVQPCTDEVVTGRALVCPVCNLEQETSDLTLFNIHVDICLNKGIIQELRNSEGNSVKQPKESSRSTDRLQKASGRTKRPGTKTKSSTLKKTKPRDPRHTLDGFFK
What is the function of this protein?
DNA polymerase specifically involved in DNA repair.  Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls (PubMed:12432099).  Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts.  Lacks 3'-5' proofreading exonuclease activity.  Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity (By similarity).
What are the official names of this protein?
DNA polymerase kappa, DINB protein, DINP.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Nucleus. Note=Detected throughout the nucleus and at replication foci. Recruited to DNA damage sites in response to ultraviolet irradiation: N6- methyladenosine (m6A)-containing mRNAs accumulate in the vicinity of DNA damage sites and their presence is required to recruit POLK.
Protein: RAB1A_ARATH
Sequence: MSYAYRFKYIIIGDTGVGKSCLLLKFTDKRFQAVHDLTIGVEFGAKTITIDNKPIKLQIWDTAGQESFRSVTRSYYRGRAGTLLVYDITRRETFNHLASWLEEARQHASENMTTMLIGNKCDLEDKRTVSTEEGEQFAREHGLIFMEASAKTAHNVEEAFVETAATIYKRIQDGVVDEANEPGITPGPFGGKDASSSQQRRGCCG
What is the function of this protein?
Intracellular vesicle trafficking and protein transport.
What are the official names of this protein?
Ras-related protein RABB1a, AtRABB1a, Ras-related protein Rab2B, AtRab2B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RL16_CHLTE
Sequence: MLMPKRVQYRKTQRGRMKGNAQRGTAVTFGSFGLKAMEPAWITSRQIEAARIAMNRYMKRDGKIWIRIFPDKPVSKKPAETRMGSGKGSPEFWVAVVKPGRVMFEADGVPREVAVEAFRLAAKKLPIKTKFIVRPDYEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PG049_VACCP
Sequence: MGTNGVRVFVILYLLAVCGCIEYDVDDNVHICTHTNVSHINHTSWYYNDKVIALATEDKTSGYISSFIKRVNISLTCLNISSLRYEDSGTYKGVSHLKDGVIVTTTMNISVKANIVDLTGRVRYLTRNYCEVKIRCEITSFALNGSTTPPHMILGTVDKWKYLPFPTDDYRYVGELKRYISGNPYPTESLALEISSTFNRFTIVKNLNDDEFSCYLFSQNYSFHKMLNVRNICESKWKALNNNDNASSMPASHNNLANDLSSMMSQLQNDNDDNNDYSAPMNVDNLIMIVLITMLSIILVIIVVIAAISIYKRSKYRHIDN
What is the function of this protein?
Plays a role in the spread of virus to neighboring cells ex vivo.
What are the official names of this protein?
Protein OPG049, 36 kDa major membrane protein F5.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG049 family.
Protein: BBP1_ZYGRC
Sequence: MSSEQVDENTSGGIHGLYRWTMDALFGSRVSPSRKYREFAQDDTNYKSRDELFKGSYKDGNSRGRSNSWSGLDPNFYRRHDLLPLEESQSSSKSSLMDPVDLHPRAPASPVLDTTDTFGAKKGSWRRSESTIEFKSPSADDPVVSRLFEKRKPRHKENVITQRLAPQIPGKFPSPVKGPSSDYTSEYLEILNQLDRNGRALQEVNRGLWERCEQRQRQEKSYRDSYRETRAELINELKQSRKLYDNYYKLYGKYQQLKAISKETLDLQSKVNNLESELVDTAIKKEKQIHDLHKQLFQAELRAQEAESRRQRDAIAYESRIADLQRQLENRYRPSSPVSYRDQSTLSDYNASVDTQFLKNLV
What is the function of this protein?
Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.  Connects the central plaque of the SPB with the half-bridge.  Required for proper localization of CDC5 at the SPB and for proper M-phase progression (By similarity).
What are the official names of this protein?
Spindle pole component BBP1.
What is the protein family that this protein belongs to?
Belongs to the BBP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Associates with the periphary of the central plaque.
Protein: Y2239_ARATH
Sequence: MVVMKLITMKIFSVLLLLCFFVTCSLSSEPRNPEVEALINIKNELHDPHGVFKNWDEFSVDPCSWTMISCSSDNLVIGLGAPSQSLSGTLSGSIGNLTNLRQVSLQNNNISGKIPPEICSLPKLQTLDLSNNRFSGEIPGSVNQLSNLQYLRLNNNSLSGPFPASLSQIPHLSFLDLSYNNLRGPVPKFPARTFNVAGNPLICKNSLPEICSGSISASPLSVSLRSSSGRRTNILAVALGVSLGFAVSVILSLGFIWYRKKQRRLTMLRISDKQEEGLLGLGNLRSFTFRELHVATDGFSSKSILGAGGFGNVYRGKFGDGTVVAVKRLKDVNGTSGNSQFRTELEMISLAVHRNLLRLIGYCASSSERLLVYPYMSNGSVASRLKAKPALDWNTRKKIAIGAARGLFYLHEQCDPKIIHRDVKAANILLDEYFEAVVGDFGLAKLLNHEDSHVTTAVRGTVGHIAPEYLSTGQSSEKTDVFGFGILLLELITGMRALEFGKSVSQKGAMLEWVRKLHKEMKVEELVDRELGTTYDRIEVGEMLQVALLCTQFLPAHRPKMSEVVQMLEGDGLAERWAASHDHSHFYHANMSYRTITSTDGNNQTKHLFGSSGFEDEDDNQALDSFAMELSGPR
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At2g23950.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: URED_PROMP
Sequence: MAKSSWEGNCFLNFFNNKSSSGKDDKTIFKSKFTSPYKLLKCSYDQEGRCILPILHTAGGLVGGDLLEFEANIGINSKVLLTTSSAQKVYGSVGRSKINPEGTFSSQKTKISILDNSHLEYLPQETIVFANGLYSQEFNIKISDNSSFLFTDLIRLGRSSAGESIESGVFRSKLEIMRNGNLCDDWEFVDQIELTKFSFEAKSGMDFKPVFGSLIWICEKEFPITKISYLKEKIKIIFKENNNYLSLGTLENGLSIRFLGTSSQDARKCFFSIWTQIRTVCGFCKPEYQGVWPLQDL
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6P_BPM13
Sequence: MPVLLGIPLLLRFLGFLLVTLFGYLLTFLKKGFGKIAIAISLFLALIIGLNSILVGYLSDISAQLPSDFVQGVQLILPSNALPCFYVILSVKAAIFIFDVKQKIVSYLDWDK
What is the function of this protein?
Plays essential roles both in the entry of the viral genome into the bacterial host and in budding process.  The formation of the G3P-G6P complex termed adsorption complex is essential for correct termination of filamentous phage assembly.
What are the official names of this protein?
Head virion protein G6P, Coat protein D, G6P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G6P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Multi-pass membrane protein. Note=Prior to assembly, G6P is found associated with the bacterial host inner membrane. There are about five copies of G6P in the mature virion. They are located together with G3P at the head side of the filamentous virion.