PharMolix/UniProtQA huggingface dataset:
Protein: LCAT_MYOGA
Sequence: FFTIFLDLNMFLALGVNCWIDNTRVVYNRSSGRMSNAPCVQIRVPGFGKTYSVEYLDDNKLAGYMHTLVQNLVNNGYVRDETVLAAPYDWRLEPSQQEEYYQKLAGLVEEMHAAYGKPVFLIGHSVGCLHVLYFNQGIPIMSSIKLREEQRITTTSPWMFPARRVWPEDHVFISTPNFNYTGQDFKRFFEDLYFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPSTYIYDHSFPYKDPVAALYEDGDDTVATRSTELCGQVQGSQSQPVHWLPMNWTEQLNMLFSN
What is the function of this protein?
Central enzyme in the extracellular metabolism of plasma lipoproteins.  Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs).  The cholesterol ester is then transported back to the liver.  Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines.  Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels.  Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins.  Required for remodeling high-density lipoprotein particles into their spherical forms (By similarity).
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma. Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (By similarity).
Protein: ISPD_PSEPW
Sequence: MIKTLPAFWAVIPAAGVGARMAADRPKQYLQLGGQTLLEHSLDCFLGHPTLKGVVVSIAADDPYWPGLRCASDPRIQRASGGRERADSVLNALLLLHAQDAADTDWVLVHDAARPNLARTDLDRLLSELADDPVGGLLAVPARDTLKRADANGRVSATVDRSTIWQAYTPQMFRLGALHRALAECLVSDVVVTDEASAIEWSGQAPRLIEGRSDNIKVTRPEDLEWLRQRWAGRR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: DTD_CANGA
Sequence: MRIVIQKVSQAMVKVDNEIVSQIAKGYMLLVGISTEDTIADAQKLSNKVLNLRLFETGDQFWKHSIQDVQGEILSVSQFTLMARTKKGNKPDFHKAQKGEHAQELYNQFLDLLKTTLGADKVKDGQFGAMMSCSLTNEGPVTIILDSTE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESFU2_ECO57
Sequence: MINNVSSLFPTVNRNITAVYKKSSFSVSPQKITLNPVKISSPFSPSSSSISATTLFRAPNAHSASFHRQSTAESSLHQQLPNVRQRLIQHLAEHGIKPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPLPVQNEQSRPLPDVAQRLVQHLAEHGIQPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
What is the function of this protein?
Required for efficient pedestal formation in host epithelial cells during infection.  Acts as an intermediate between Tir (via host BAIAP2) and host WASL/N-WASP.  Directly binds and activates WASL/N-WASP, which stimulates actin polymerization and leads to the formation of actin pedestals at the sites of bacterial adhesion (By similarity).
What are the official names of this protein?
Secreted effector protein EspF(U), EspF-like protein encoded on prophage U, Tir-cytoskeleton coupling protein TccP.
What is the protein family that this protein belongs to?
Belongs to the EspF(U)/TccP family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (TTSS). In host cells, localizes to the tip of the actin pedestal (By similarity).
Protein: IDI_ECOSE
Sequence: MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDFRYRATDPNGIVENEVCPVFAARTNSALQINDDEVMDYQWCDLADVLHGIDATPWAFSPWMVMQAANSEARKLLSAFAQHN
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTND1_MOUSE
Sequence: MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANSLMANGTLTRRHQNGRFVGDADLERQKFSDLKLNGPQDHNHLLYSTIPRMQEPGQIVETYTEEDPEGAMSVVSVETTDDGTTRRTETTVKKVVKTMTTRTVQPVPMGPDGLPVDASAVSNNYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYGRHYEDGYPGGSDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDLDYGMMSDYGTARRTGTPSDPRRRLRSYEDMIGEEVPPDQYYWAPLAQHERGSLASLDSLRKGMPPPSNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPILVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEALPTVANSTGPHAASCFGAKKGKDEWFSRGKKPTEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIAELLTSEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKSDKKPDREEIPMSNMGSNTKSLDNNYSTLNERGDHNRTLDRSGDLGDMEPLKGAPLMQKI
What is the function of this protein?
Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability.  Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics.  Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
What are the official names of this protein?
Catenin delta-1, Cadherin-associated Src substrate, CAS, p120 catenin, p120(ctn), p120(cas).
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cytoplasm. Nucleus. Cell membrane. Note=Interaction with GLIS2 promotes nuclear translocation (PubMed:17344476). Detected at cell-cell contacts (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm (By similarity). CDH1 enhances cell membrane localization (By similarity). SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: Y2503_PHOLL
Sequence: MTELCPCGSGIDFADCCSPYLQNIKFAQTAESLMRSRYSAYVKHNADYLITSWHPDCQAEKWRLDIEQSFIVTQWLGLNVITTEKGENDNEAYVEFSACFLDQKSQDKQLIHERSRFLRIDQHWYYIDGVKPIDGIKPQIGRNSPCPCGSGKKYKKCCG
What are the official names of this protein?
UPF0225 protein plu2503.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: SYA_HERA2
Sequence: MKGSELRQRFLDYFARQGHAVVPSSSLIPADNPTLLFTVAGMVQFNDVFLGRESRPYSRAVSSQKCLRISGKQNDLENVGPSPRHHTFFEMLGNFSFGDYFKKDAIRFAWEFLTQEIGLDPKRMWVSIYEGDEQIPADEEAHDLWLAYMPAERILRFDAKDNLWSAGDVGPRGPCSEIHYYIGDDPDNQVPEGVNSEDDTYMEIWNLVFMQYNRDENGVLTLLPKPSIDTGMSLERLAIVKQGVFRSYETDLFTPIIHTVMELLGTGSDHYQANSSAYHVVADHSRSIAFMIADGLRPGNEGRSYVLRRLVRRAAYFGQTIGFKAPFLAETIATVIDMMGAAYPELRSKQAYIAEVVTGEEERFNKTLAGGLRQLEAMLPNQADKAVFSGADAFKLYDTYGFPLDLTERIVAERGLTVDLAGYEAELEAQRARGRGAAQFKKGAVTERWAERNLAPTSFTGYNELESWGHVLALEFDGEELGTVQRGQEVAFVLDRTPCYAESGGQMGDSGVLVGPHGTIVIDDVQKPVPGVFVHRGKVSKGSVSLGEQVTVTVDAARRRDIVRNHTATHLLHRALRDTLGDHAEQKGSLVAPERLRFDFNNQKGLSSEQLQQIEDQVNAWIRADSKVEAAEMALPQARELGAMALFGEKYGDVVRVVTVGCGNASDHIHTNSEAPVCSRELCGGVHVARTGEIGFFKIVSEGSVASGVRRIEAVTGRAAAEWVSQQAQLIRTLGDKLGAQPGKVEEKLDALLLDQKARRDEIERLRGEIAAGQVDSLLAQKIEQAGTPLVVARVEASDADSFRRLGEQLRDKIGSGVVILGTVIDGKPLLLAAATADQVKAGRHAGNLVKALAAKVGGGGGGRADFAQAGGRDAAALDQALAEANGLL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYOZ1_HUMAN
Sequence: MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGGSGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITVFKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL
What is the function of this protein?
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere.  Plays an important role in the modulation of calcineurin signaling.  May play a role in myofibrillogenesis.
What are the official names of this protein?
Myozenin-1, Calsarcin-2, Filamin-, actinin- and telethonin-binding protein, Protein FATZ.
What is the protein family that this protein belongs to?
Belongs to the myozenin family.
What are the subcellular locations of this protein?
Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle.
Protein: Y378_NANEQ
Sequence: MKIKYMGHSAFIIEHKNRLIIDPYIETIPEVDYVLVTHAHNDHFGNTIEIAKKNNAKVISIYEIAEFVKQFNIESIGMNFGGTIDIGEKVSLVPAVHSSTLYYNGKAYPLGNPGGFVIKGNKTIYHAGDTMVFKDMELIGELFKIDVALLPIGGVFTMDIDQALKAIDLLKPKIVIPMHYNTWPIIKADPYEFKRKAEEKGVEAIVLNKDEEIDL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase NEQ378.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: GATY_ECOLX
Sequence: MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQNLRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPVLDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTAHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol (By similarity).
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: YDIK_SHIFL
Sequence: MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTVVIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISSGDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHIGRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGVVVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTTWGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLLAVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKPNK
What are the official names of this protein?
Putative transport protein YdiK.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXD_PARDP
Sequence: MTLTIAELARALDARLWGDGSLIVNGAAEAGQAGEGQIALATSPAYAEKLSPGGMALLAEGADPEALGLRAAILVGRPRLAMAGLTRAFDPGPGIAPGIHPSAVIDPTAELPEDAAIGPFVVIGPRVRIGAGARIASHVSIGADTVIGRDALIHAGVRIAHGVTIGDRVILNPGVSLGADGFSFVTPEKSGVEEIRQSLGERQEIRQQHWTRIHSLGGLEIDDDVEIGANSTVDRGTIRATRIGRGTKIDNLVQVGHNCVVGEDCLLCGLVGVAGSARIGNRVVLGGQVGVSDNIFVGDDVIAGGATKIFTNAPAGRVLLGSPAVRMETHVEAQKNIRRLPRLYAQVAELRETVKKLLDKGDVE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SYA_MESM1
Sequence: MKSKEIRNKWLNFFESKGHLIIPSKSLIPIKDDSLLWINSGVATLKDFFSGKKIPPSKRLTNSQKSIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKKEAINFGFEFIFDVLKFDREKIFFTYFSEDLETLEILKSLNVPDSQIIKGSRKTNFWDMGNGPCGPNLEIFYDRGPKYSNRGIELLKNDIENDRYIEIWNIVFSQFNNDGNGNYELLKQKNIDTGAGLERLACILQDTPTNFETDLFLPIIKEIEKLSIYKYKIDNYFLKDKIQEKINLNFKIISDHLRTAVNAINDGAKPSNNGRGYIIRRLIRRAYRSGIFLGIKGKSFLHKMTQIVRDSLIYDIDVEKVSKIIKKEEEMFSKTISEGINLLKEKIKSKFPKDNSIDIENKSQVAKYFKENNLTFDFSIAFELFSTFGFPVEIIKEILEDEYEIELDISNLPKYLEEHANKSRSENSSAMQKVINSLELVKEKVSEFVGYSTLKTKSKILYLLNETEEIHFTNSENEISYLILDKTPFYATAGGQRHDKGLLIQDKNRIEVLEVFKDKHLNNVHKVKGKILKSELINAEVDSNIRIGLERNHSGTHLVFNALSREFGKEIEQLGSDNNEERLTFDFPLSKKPSWEEIKNVEKRVNEYINMSVDREYIITTLEGAKKLNAVMTLEEQEYMDPNEVRIVNFPKITADLCGGTHIENTKKIETFKIISLDSKGKNKFRIKAITSKKIVEEYLKDEISKNKLVLENLIEKNKSLFQGYKMNFSWSKNLDEQNEQITKHIDQARSDYKKLLKNSENKLEKLESDFSIMKFKNTEIIFDMNLKMASLQSLVATLREKNPKAIVILGSEISKGKFFICVGSKEFSAKDISNIIFEKYKGKGGGNNILSQGSIDKKIEKAEDLFELLKEKGII
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: PSUG_JANSC
Sequence: MTLPLTFSPEVAEARAAGAPLVALESTIITHGMPYPQNLDTARAVEAEVRAAGAVPATIAIMDGRMHIGLTGTELEVLAQADGVAKLSRADLAACLARGGVGATTVAATMICAALAGIHVFATGGIGGVHKGAEDTFDISADLRELAHTPVTVIAAGAKAILDLPKTLEVLETLGVPVIAHGQDAFPAFWSRDSGLPAPLRADSATEIARAHLMRSKLGLPGGQLVANPIPEDAEIPASTLAPLIVQAQSEADAKGVARKAVTPFLLNRLFELTDGATLASNIALVLNNARLGAAVARALTT
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: CASP3_XENLA
Sequence: MEESQNGVKYGGDATDAKEYFTIQPRSLQNCDLKDIERKTKFAHLQNYRTNYPEMGMCLIINNKNFHSSNMAVRNGTDVDALKLHETFTGLGYEVMVCNDQKSSDIIGRLKKISEEDHSKRSSFVCAILSHGEEDGSICGVDVPIHIKNLTDLFRGDRCKTLVGKPKIFFIQACRGTELDSGIETDSCSEPREEIQRIPVEADFLYAYSTVPGYCSWRDKMDGSWFIQSLCKMIKLYGSHLELIQILTCVNHMVALDFETFHAKKQIPCVVSMLTKSFYFFK
What is the function of this protein?
Important mediator of apoptosis.  At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond (By similarity).
What are the official names of this protein?
Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, xCPP32.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y581_MYCPN
Sequence: MQLEKVPRAEYQTKWATNTVPKPTDFYHQLYNLSFSLTLTSQRWNTYGTGWLIDWKDTSTNENKFTAYLATNFHVADTLKNPHDYPPYNQVDNTQDLTTSFRIGKYTDPSLFGLYTNVKHAFVDVQLAALPKMAYAAVDFVDYRFDNKHWKSLNEICPEVGLKPYADFAVLEVPLYLNNKLDYQVWENFIKPAIATYKALGDSTNLFASTSSSDLQNDTYFALGYPLLESNIDAIHFNQTGATLTSVPVKDRIKVKNQSFWTLNK
What are the official names of this protein?
Uncharacterized protein MPN_581.
What is the protein family that this protein belongs to?
Belongs to the MG067/MG068/MG395 family.
Protein: ERPA_SHEB5
Sequence: MTDQADTAMPIQFTDAAAAKVKGLLEEEQNPALKLRVYVTGGGCSGFQYGFTFDEKVNDGDFTIEKQGVLLVVDPMSLQYLVGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: L_MMVR
Sequence: MDPDYPDLDPESLDVLNSLQEGYDEEEEEDSGVSLNGMGDYHLKSALRSYTDMMKHPIFKKEFSKAVINFGISHDSMMSQIETMFYILKSTPLSMHLGTLYGDLFTRQSTLGHSEDVFDIIQAEIRTLHPHLLLEMTPAKVEEMVLIADRKTYDERAASAFWSTLITIKNYIPAWTEKGACTLDWPSVSLDKKSGYVKVMAGKDTTIYIGTDICVIEKYPTVKWAPLSYLLNGADKVAERLNVRYYSCLCDQLDIPDRITLDMLDEIIKVGDDCLREMGNDGYNVIGSYEALLAGIIQRRDNQGLIPDRDLLWRTTMEEFTSSPGRKYLEEWSTMFSSLSPEQIACAHGLYRIWGHPIVDILGGIKKMQEVASVKKNPRQSVLDEIRRQFKEMFFTSYHRIHKHYPLHTILNSLDNSYILNCLKDNLTINTSAISYNFQDWDCVMVEKNFEVPFSWNLVHNLKDKAISPNRQEIYQTISTRGTIFGSQNRRGILKSLTMETVQLRDFLQGINDNGLDDIDKIIGVYPKERELKIKARLFSLMSFRLRLYCVSTEALLGDKILKYFPQITMSLDMLTMIKKMFKVSSQTTREDDSVTVIFNLDFIKWNLQMRRNICEPVFSQLGKLFGMENLFNRTHETFRDSLIYLCSGEGVLSADPVYGVFPDGTWAWAGDESGKEGLRQKGWTILTVVTIMLIAKRHNVDVSLMGGGDNQVLGITISGVTRDLQGELITESASLARRTIKQFTEDLLTTFSDLGLPLKASETWVSDSLFMYNKHMFYKGIPLRSPLKAISRIFPLANDTIMTIDNMINNISSGVKAACMKERHGIPLVFMKTLAYRKVAEGALILHPLTTCFRTPTLPENGTVTRDGRKRSVKVTRNQLRSFFTLCMVGSSTMGLPGTIHLPDMIMRGFPDPLTSHLSFISELVPKIMDPRLASIIATSGHMSINRMTEYAKLVEDPVSINHDAPTHGLNEIRQLSRDFLMNTTLAANTHLKSLFTLLDRQREKEFYDALCSAEELDVKVLHEVAGASLFGYTNGIASRIDQTRTVRALNETVNVMKRLADAEARYIAYLFARDIHKHDLIPDQCSRVTADRYRYYSWKKKVLGVTVPHPIEMCQVTSATQTAFEDAVICWSDNLSGSRIYTTMGLGKIYQGSYTKERFKATDIAAAYGNEDILTKAVRLQKLINWRYDEGSSFARIIQLALRAITDASTDGFHRXKEEIKGEFDHRRGISGDISGGIPNFLVTPTSHXSCTTSSWISHSRGGKNENIHFQSVLINLLYRAMVYRGSLPGLPEMVWYSKERCSHCIIDIVEPSPERTTPALSEMPSAPNNPFAFIESVNVKLDYHHQVEIEKGMEETNLLNSEWGGSSLTSVDEAGLVLFLMLIGSRQVSESFLLLMREKIEPRPLLQAALNRVILVRKLGLDRLFPIRNTKCINLILGSDRGITACHDGFGLELHGGSWEKGIECDTSFLYNDTHLKPCKLHVNLHLQNVPLQLALAHASYNPDVCECLECRAIIEDRVSKRMVGQYKSWRCQYHAVLSFSPIIMRVHSERIIKSEGAIYEGDLHVPYVEEIIALENSQKLAIDVTSWRLPLLMHATWESILPQLYITMKACLVSLPLEGVIVDDDLALINLVSKVLVDLRRTIQVYIRAGTFSGSEINNKYDNIRLLPEDLRDSIHILTTTDKPDPAATVQLAADDTSPLDCAVYHLIWGDTWGMTRKVHGRILIPSSRVTTGFAGVMVTDYYATVAVLELAGAVNLWEKKLIDLEHRNNLDVPLSMNRVLAGSRLGTRGIRWAQWTSPAGLEIVVRKVRAKLSSISGNPGNAAKWRRNCQKVLKALMISLYAHSGEDMMRNASGLVKVNIHGTLSSVTAVCDPSAESRVQRAQFLFLKEKAPNGPFIXRSRLERRINLLSVVSDLLG
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviridae protein L family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=L and P are packaged asymmetrically towards the blunt end of the virus.
Protein: SYFA_CHLTA
Sequence: MTIQEELEAIKQQFSCDVSLAHSSKDLFDVKVKYLGKKGIFRGFADQLRKCPIEQKATVGASINACKQYVEEVLLERGKAVLAKEEAEEFLKEKIDISLPGSEEAALGGKHVIKKVLDDVVDIFVRFGFCVREAPNIESEKNNFSLLNFEGDHPARQMQDTFYLDPTTVLRTHTSNVQSRELARNKPPVRIVAPGECFRNEDVSARSHVIFHQVEAFCVDKDISFSDLTSMLAGFYHIFFGRKVELRFRHSYFPFVEPGIEVDISCECHGAGCSLCKHSGWLEVAGAGMIHPNVLRKASIDPEEYSGYALGMGIERLAMLKYGISDIRLFSENDLRFLRQFS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXA_ECODH
Sequence: MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: RL36_LISMH
Sequence: MKVRPSVKPMCEKCKVIRRKGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RSMA_MYCTO
Sequence: MCCTSGCALTIRLLGRTEIRRLAKELDFRPRKSLGQNFVHDANTVRRVVAASGVSRSDLVLEVGPGLGSLTLALLDRGATVTAVEIDPLLASRLQQTVAEHSHSEVHRLTVVNRDVLALRREDLAAAPTAVVANLPYNVAVPALLHLLVEFPSIRVVTVMVQAEVAERLAAEPGSKEYGVPSVKLRFFGRVRRCGMVSPTVFWPIPRVYSGLVRIDRYETSPWPTDDAFRRRVFELVDIAFAQRRKTSRNAFVQWAGSGSESANRLLAASIDPARRGETLSIDDFVRLLRRSGGSDEATSTGRDARAPDISGHASAS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.