PharMolix/UniProtQA huggingface dataset:
Protein: LPXH_PSEPW
Sequence: MILLISDLHLQEERPDITRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAVRQLSDSGTAVYLMHGNRDFLIGEGFCKAAGCTLLADPSVISLGGEQVLLMHGDTLCTRDIGYMKMRRYLRNPLSLWILRHLPLATRQKLARKLRSESRAQTRMKATEIVDVTPEEVPAVMAAHGVKTLVHGHTHRPAIHKLVVNGEPARRIVLGDWDRRGWTLQVDAQGFQLEPFEFS
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FRIG0_ARATH
Sequence: MSNYPPTVAAQPTTTANPLLQRHQSEQRRRELPKIVETESTSMDITIGQSKQPQFLKSIDELAAFSVAVETFKRQFDDLQKHIESIENAIDSKLESNGVVLAARNNNFHQPMLSPPRNNVSVETTVTVSQPSQEIVPETSNKPEGERICELMCSKGLRKYIYANISDQAKLMEEIPSALKLAKEPAKFVLDCIGKFYLQGRRAFTKESPMSSARQVSLLILESFLLMPDRGKGKVKIESWIKDEAETAAVAWRKRLMTEGGLAAAEKMDARGLLLLVACFGVPSNFRSTDLLDLIRMSGSNEIAGALKRSQFQV
What are the official names of this protein?
Inactive protein FRIGIDA.
What is the protein family that this protein belongs to?
Belongs to the Frigida family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2164_RALPJ
Sequence: MIIVLSPAKSLDYDTPPRTKTHTLPDFIERSAELIDVLRKLSPAQIGTLMHISDPLAALNATRYADWSPEFTAENSKQAALAFDGDVYGGLDANSLAVDDLQFAQKHLRILSGLYGVLRPLDWMQPYRLEMGTRLANPRGKDLYAFWGDDVTLALNELFKQDDDAVLVNLASEEYFKVVRPKVLKARIVTPVFEDWKNGQYKIISFYAKRARGLMARYAIEHRITDPRKLKAFDVDGYAFAAADSDDERWVFRRKLT
What are the official names of this protein?
UPF0246 protein Rpic_2164.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SLX1_KLULA
Sequence: MSNKQHRVPDFYCSYLLRSIPKPNSFYIGSSPDPVRRLRQHNGAVRRGGAYRTKRNGTRPWKMVCFIYGFTSKIAALQFEHAWQHSYKTRFIENNERLVTKKNTRNGIATKLGNARLLMKHPYFDKMNLHIRFFDRLAWESWELNKFKVDYGLSLCEVDEAVLTDESQLDELDELNLERIKAFYEDQMAQESSLLQRYQDNLTYDQKSCMICDKKIDYIHDEGTQMVGFCSDDECDFLSCLSCLYKEFTKNSKQIIPKSGHCPNCHKCLEWSQIVKYSTVLREKLIKD
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUCC_HISS2
Sequence: MNLHEYQSKKLFADYGLPVTKGYVCENVEQALSAIEKLSGSQWIAKCQIHAGGRGKAGGVKVVKSAQEVRSFFTKFLGQRLVTVQTNEQGQPIHQIYLEPCAEIQKELYLSAIIDRSSQRIVFMASSEGGMDIEEVAEKTPHLLHRVTIDPLVGAMPYQGRELAFKLGLSGKQIQQFSQIFCQLAKLFVEKDLSLLEINPLVILKNDELFCLDAKVVVDDNALYRHPDLFSMRDLTQEDPREAEAEKWNLNYVALDGNIGCMVNGAGLAMGTMDIIKLHGGRPANFLDVGGGATKERVMEAFKIILTDSAVKAVLVNIFGGIVRCDLIAKGIVSAINEIGVSVPVIVRLEGTNADLGREILAQSNLNLIAVNSLTEAAEQAVNAAKESE
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: CLCA_ECO45
Sequence: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASARENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YAFQ_HAEIN
Sequence: MSEEKPLKVSYSKQFVRDLTDLAKRSPNVLIGSKYITAIHCLLNRLPLPENYQDHALVGEWKGYRDCHIQGDLVLIYQYVIQDEFDELKFSRLNIHSQTALK
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its cognate antitoxin is RelB (By similarity).
What are the official names of this protein?
Putative toxin YafQ.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family. YafQ subfamily.
Protein: TBX1_HUMAN
Sequence: MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGGHVLKDKEVKAETSRNTPEREVELLRDAGGCVNLGLPCPAECQPFNTQGLVAGRTAGDRLC
What is the function of this protein?
Probable transcriptional regulator involved in developmental processes (By similarity).  Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence (PubMed:11111039).  Is required for normal development of the pharyngeal arch arteries (By similarity).
What are the official names of this protein?
T-box transcription factor TBX1, T-box protein 1, Testis-specific T-box protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAE_ALKCK
Sequence: MRIGLTGGIASGKSLVATYLEKQGIPVVDADKLARQVVEPGEPALAQIVATFGEHVLQDDGTLDRKQLGAIIFGDEQKRKQLNEIVHPAVRQSMKKQADLYEQRGYTRVVLDIPLLYESNLFHMVNQVWLVYVDEATQLRRLIERDGLTETEAKQRIAAQMPLTAKKAQADVLIDNNGTKENTYRQVYDALAKTAHE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_BACP2
Sequence: MNEEQRKASGQVSSSDKKSEKDYSQYFEAVYIPPSLKDAKKRGKEEVEYNQFQIDERFQGLGNGRKFYIRTYGCQMNEHDTEVMAGIFMALGYEPTNSTEDANVILLNTCAIRENAENKVFGELGHLKALKREKPDLILGVCGCMSQEESVVNRILKKHPFVDLIFGTHNIHRLPELLSECYLSKEMVIEVWSKEGDVIENLPRARQGKIKGWVNIMYGCDKFCTYCIVPYTRGKERSRRPDEIIQEVRRLAAEGYKEITLLGQNVNAYGKDFEDMEYGLGHLMDELRKIDIPRIRFTTSHPRDFDDHLIEVLAKGGNLLDHIHLPVQSGSSSVLKLMARKYDRERYLDLVRKIKEAMPNASLTTDIIVGFPNETDEQFEETLSLYREVEFDAAYTFIYSPREGTPAAKMQDNVPMHVKKERLQRLNALVNEISAKKMKEYEGQTVEVLVEGESKNNPEILAGYTSKSKLVNFKAPKEAIGNIVKVKITQAKTWSLDGEMVGEAIEVN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_STRT1
Sequence: MAFAKISQVAHYAPAQVVTNDDLSKIMDTSDEWIRSRTGIQERRISLNENTSDLATNVAYQLLEKSGLSPEELDFVLVATISPDNSMPSVAARVQGTIGAVNAFAFDITAACSGFVFALATAEKLIKSGAYKKGLVIGAEVLSKTLDWSDRATAVLFGDGAGGVLLEESEEEHFFGESLNTDGSKGGLESGASAVISPYSDGTEQPNPYMQMDGKAIFDFAVKTVSKSIKALVEEKGEPDYFLLHQANIRILDTMAKKIDVSRDKFLANMMSYGNTSAASIPILLSENVANETLKLGSDQTILLSGFGGGLTWGSLIVKI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4120_PSEPG
Sequence: MKRICSIYKSPRKNEMYLYVLKADGLERVPEGLLPFFGTPMHAFDLVLSPERKLAREDITKVLENLDNQGYHLQMPPAEDEYIEHLPEELLRRNDPV
What are the official names of this protein?
YcgL domain-containing protein PputGB1_4120.
Protein: GPMI_IDILO
Sequence: MTPTIKPLVLLILDGWGYREDAPDNAIAKANTPVMDRLWEKYPHCLVDGSGGAVGLPDGQMGNSEVGHVNLGAGRIVYQDFTRISKAISDRSFFSNTILCDALKKAKAAKGAVHIMGLLSAGGVHSHEDHLVAMIEMAVEQGAEDVYLHAFLDGRDTPPKSALPSIERFEALFARLGKGRFATLSGRFFAMDRDKRWERIEQSYKAVYHGLSGVTSANATDAVENAYERGETDEFVTPVVIGQPAPIANGDSVFFMNFRADRAREMTQAFVDKDFDGFDRGSRADISEFVMLTQYADTLEAPSAFPPEPLNNVLGEWLAKHDKTQLRISETEKYAHVTFFFSGGREQEFEGEKRVLIPSPKVKTYDLQPEMSSEQLTDELVAAIESQAFDVVICNYPNGDMVGHTGNFDAAVKACEAVDHSVGRVVSALEAVGGECLITADHGNAEQMSDATTGQAHTAHTNELVPFIYVGRPAKARNGRLSDVAPTILHLIGMEQPDEMTGTSLMTLEQD
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: MTQ1_YEAST
Sequence: MPRISTSLIRKASRIRPGLHLLLPECRTLEQAKLEYKWLTEELPPDKSIRWACLQRYKHVPLQYILRSQPFGALDIVCKPGVLIPRWETEEWVMAIIRALNNSMLSRHTIPLHICDTFTGTGCIALALSHGIANCTFTAIDVSTRAIKLVKENMLKNKVSGGKLVQHNILSSKASDEYPSHIDILTGNPPYIRKRDFNRDVKTSVKLFEPRLALVGELECYINLVNYWLPKTDSFFYEIGDVEQFNYVERRIKEDSYLSRIWSIGLKYDSNGKARVVYGFKATPKGRILHQIFASFGTIRHLATALSGHKANCN
What is the function of this protein?
Methylates MRF1 on 'Gln-287' using S-adenosyl L-methionine as methyl donor.
What are the official names of this protein?
Mitochondrial MRF1 N(5)-glutamine methyltransferase MTQ1.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PAND_MYCLB
Sequence: MLRTMLKSKIHRATVTQAYLHYVGSVTIDADLMGAADLLEGEQVTIVDINNGARLVTYAIAGERGTGVIGINGAAAHLVHPGDLVILISYGTMEDAEAHAYQPRIVFVDADNKPIDLGHDPGSVPLDISVAAELFDPRIGAR
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1768_BACVZ
Sequence: MISKEKIARINELAQKAKSNTITDEEKAEQQKLRQEYLKGFRSSMKNTLKSVKVIDPEGNDVTPEKLKREQQKNNLH
What are the official names of this protein?
UPF0291 protein RBAM_017680.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y111_ATV
Sequence: MGKSMEEGIFVKVFPSKAIFVIYKEVEIIVKPDYAGDTIKVKYVFNSDELQKKLVEYFNKFNVPYKEISKNEVEVYYDPMYQLDCFDHMFEKLTMGDTDYIDSILGRLLPI
What are the official names of this protein?
Uncharacterized protein ORF111.
Protein: PYRDB_PARD8
Sequence: MAELNVNIGNLPLKNPVMTASGTFGYGIEYADFMDISRLGGIFVKGTTIQPREGNDYPRMAETPSGMLNAVGLQNKGADYFAEHIYPKIKDINTNMIVNVSGSSVETYVECAEKIAELDRIPAIELNISCPNVKQGGMAFGVTTCGAGEVVKAVRRVYPKILIVKLSPNVTDITEIAKAVEAEGADSVSLINTMLGMAIDAEKRKPILSTITGGLSGPCVKPVALRMVWQTYHAVKIPIIGLGGISNWKDAVEFMLAGASAIQIGTYNFVDPTVSIKVIDGLNDYCDRHGFKSVKELIGALDIQR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT12_MACFA
Sequence: MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKISSTKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRLEKPETQSSPITVQTSKDLAMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPAVKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKTSSAGPSTAKLSSTTQNSTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPLKPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGNSSQLSGNGNTGTSGPSGSTTSKTTSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 12, Int12, PHD finger protein 22.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PKS81_PSEFD
Sequence: MEFVYFSNEFPKDDLHDIYRGLHNHSKHRDFPLLARFLNEATAAVKDEVRRLPTELKRLIPPFDNLLSWVENKELREGLLCGAIDGVLLIVAQVASYIGYVESHPEELRNMSEASLAGLGIGLLASTAISLSTEQADLPLAGADAVRLAFRMGVHVFGVSENLEARDLSEKPETWACVVHNVDPAVAQKELDAMQPAGEVPETGKVFISAISRTSVTVSAPPQKLKALLNKCEFFRKARYIELPVYGGLCHAPHIYSAQDTESIVRGASLNARRKGLEPVVPVYSTSSGQPYAAKTATELFECVVSELLRQAICWDKVIAGIVDSAKRTATTEATLHCFGNSIPLNDLDKAFKSDMPELRVSTNNLVPWIFQNEPRDTAPRGPAQSKLAITGISCRFPGGATTTEKFWEILEKGLDVSRKIPADRFDIETHYDPTGKALNKSMTQYMCPIDEPGLFDAPFFNMSPREAQVVDPQMRLALVTAYEALERAGYVGNRTASTKLERIGTYYGQAADDYREVNQGQEVSTYYIPGGCRAFGPGRINYFFKFAGPSYSIDTACSSGLAAIEIACRALWNGDVDTAVTGGMNILTNPDGFAGLNQGHFLSKGHNACKTWDATADGYCRADGIGSLVIKRLEDAEADNDNILGVILGAGTNHSAEAVSITHPHAGHQAYLSRQVLRQAGVDPLDVSYVELHGTGTQAGDFEEMSGIMDVYAPLTKRRSKDQPLHIGAVKSNVGHGESVAGTTALIKVLMMLQKNAIPKHIGIKTEINPKFPKDFKQRNLHIAFEQTAWPQIPGKKRLAAINNFGAAGGNTTMVLEEGPVREKQQADPRQSHVVAVSAKTKASLTGNIERLIAYLEANPATDLADLAYTSTARRYQHTHRVAMATSDVAELTKKLTSSLSKVDSIGPVGKSGPPQVAFSFTGQGASHKSMNLELYRDVPTFREHIHHLDTIAQNQGFPSCIPALDGSFPQDHEHSPVITQLALVCTEMALAKYWASLGVKPDVVIGHSLGEYAAMHVAGVITASDAIFMVGRRAQMLQEKCKIRSHTMMAVRASVAQISESSGGKRHTIACVNGPSDTVLSGTKEQMNEIQVPLEAAGYRCIKLDVAFAFHSEQTDPILDDLEAVLESGVVFQEPKMPYISPLLGKTIFDGKTLNANYVRRATREAVNFLPAMQNAIDIEAVSEETVWVEIGPHPVCAGFIKSIVPSTQLAIPSIRRNEDNWTTMSSSMAALHLTGVALSWNEFHRPFESSLRLLDLPTYAFTEKNYWLQYNGDWCLTKGNTFYSAEKEAARAAEPQPSVGSDLQTSTVQQVIALEVEGNAGVVVMKSDLMQGDLLVAAHGHRMNGCGVVTSSIHADIAYTLGNYLYRKIKPKDKVPAMNMTDLLVTKGLVAQNKTKYPQEFRVTAATPDITSGQIMMSWQNVDDNEPFATATLILGDANDWLSSWESMSHLICSRIDSLERMAAEGKASRFTRNMAYTLFASNLVDYADKYRGMQSVVMSGLEAFADVELTTKESGTWTIAPYFIDSVAHLAGFVMNCSDAMDAAKNYCVTPGWKSMRFAKPLTAGAKYRSYVRMIPTKDDPTVYLGDVYIMQDDEIMGMVGGIQFRSYPRILLNRFFSAPDKAMTEARAGNAATVTPQVTIPKPPSSLKTPAPANPSRRDSGVESKPLPPPQPKQAPPSTDSENSTISKALTLIATEGGLEISDLGDDVSFADLGIDSLLSLVISEKFRSELGVQVSGSLVLDYPRIGDMRRWLEEHY
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of an emodin derivative that may be involved in black Sigatoka disease of banana (PubMed:27513322, PubMed:27388157, PubMed:30735556).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase PKS8-1 (Probable).  The atrochrysone carboxyl ACP thioesterase MYCFIDRAFT_190111 then breaks the thioester bond and releases the atrochrysone carboxylic acid from PKS8-1 (Probable).  The decarboxylase MYCFIDRAFT_34057 then catalyzes the concerted decarboxylation-elimination required to convert atochrysone carboxylic acid into emodin anthrone, which is further oxidized to emodin by the anthrone oxygenase MYCFIDRAFT_34418 (Probable).  The functions of the other tailoring enzymes as well as the final product of the cluster have still to be identified (Probable).
What are the official names of this protein?
Non-reducing polyketide synthase PKS8-1, PKS8-1 gene cluster protein PKS8-1.
Protein: EPSF_RALSL
Sequence: MKYSAPIRLNALSAIVSHHGVLVVIGMLLAVPMAFPLFPIAATYCAAILAILLPLGRLQHVLATASSIAFAWLLTLRNPSRGLVEAGLGDDALHYMNAFYEFQQNYCCSPLDVLKTGIRSAGGGEPIFWYLSYGVAKLFDTPLMVWAILIFISLMLVWIAIYRSTERFAYVVFVAYLSTITLYALQGSAIRQAVAVGLVMVALDLLIRRRLVWAACVGLLAAGTHSSAAALLLVCATVMLFLSKDYGMLARKASWLGQLGRLLVLLVLAVAAVAFGSAEFVMSKIQARLSENQTGSAWEFQLAVEAVLACLFAWLFRMKLPREEKLTYFLFVLLCASTSFFAPAVGARLFRYTYCFYIVYLCVFFFAREGESLGQKKTLASLLFLASLGWAFYIVDVRYQGLFVSGGVIDHFLAGPFF
What is the function of this protein?
Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor.  May play a role in export of EPS I or its intermediates across the membranes.
What are the official names of this protein?
EPS I polysaccharide export inner membrane protein EpsF.
What is the protein family that this protein belongs to?
To S.marcescens SfuB.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSA_PARUW
Sequence: MISRPISQQIYSNLNRVIPGGVNSPVRACANMGQIPMIIDHAYRDTLVDVDGKTYVDYCGSWGALIHGHAHPSILEAVQQRMKKGTSFGITTSIEGELAQEVIKLIDSVEKIRFVSSGTEATMSAVRLARGYTNKEFIVKFNGNYHGHADFFLVQAGSGVLEVSPSASSAGIPADIVKQTLCLPYNDIEACRQIFHHSDYRHKIAAIILEPIAGNMGVIPASQEFMQFLRKETLAMGALLIFDEVMTGFRVALKGAQDIYPVEPDLTCFGKIIGGGFPAAAFGGREEIMNLLAPLGSVYQAGTLSGNPIAMEAGLQSLRLIQQPGFYEELHRKTDLLLNPIKETIKKNNWPICIQQAGSMFTLFFCKNRVRNLEDALKANTTIFANFFRKLFDQGIYIPPSQHEAWFISQAHEESNLIKTQSAILTFLEENF
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEY1_CHAGB
Sequence: MNGHFAAVGNGPTAQQYEHGIQVIDEDKAFNTNLNDYLGETRVAEAGFNYHLISVFGSQSTGKSTLLNHLFKTEFSVMSESARRQTTKGIWMSKNKRAGANGDAATMADNILVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNIWEHQIGLYQGANMGLLKTVFEVNLQLFLKDRQSQTRSLLFFVIRDHVGNTPLANLRDTLVQDLTKIWSTLSKPQGLEDSKIEDYFDFAFAALPHKILQPEKFLEEADKLSTRFTTGHRSAKDQEFVGGVFLPEYHRRIPADGLSVYAEGVWDQIVNNKDLDLPTQQELLAQFRCDEISREVFVGFDSVIVPLEEQQAEATRLGKATVLPDLGVTGAGTREKCVKAFETQASRYHKGVYSVKRGELESKIDARLKALYQTQLSAAHKSGVAAFSDAVTNAVKAGQKAGGYEFAEIVDKQKKKTLEFFKKEAQSLLIQGVAWTNFKPQYRLFEKELDEVSARLRKEEMRRLAIRVERWVKSRLGDSIGVEFNKLGSGRGGSGAPENGEKPATEKDLWDRIWNTFSGIIREAETRFADRAKSFEASPEEVEVGLWRLRRKSWVALREKIEEEMMESNILMKLRENFEDKFRYDEEGVPRIWRPTDDIEGIYTRARESTLGLIPLLARFRLAETYAPPDLPTFVGPQPAGAEPEDEEDLAPIGGVDEEEGKSLEEEMTVLSESKRQDLVVRFKKMADGVYVEAKRSAIGGITQVPLYFYIVLLIFGWNEIVMVLRNPMLFMLLLVMGGGTYVAYTLNLLGPMMQMANAASNQAVEIGKEKLRDFLENNQTMRQAIAMPPRSQDNGIGMDRLDSRGKKAQEVEEDDDI
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: APOA4_RAT
Sequence: MFLKAVVLTVALVAITGTQAEVTSDQVANVMWDYFTQLSNNAKEAVEQLQKTDVTQQLNTLFQDKLGNINTYADDLQNKLVPFAVQLSGHLTKETERVREEIQKELEDLRANMMPHANKVSQMFGDNVQKLQEHLRPYATDLQAQINAQTQDMKRQLTPYIQRMQTTIQDNVENLQSSMVPFANELKEKFNQNMEGLKGQLTPRANELKATIDQNLEDLRSRLAPLAEGVQEKLNHQMEGLAFQMKKNAEELQTKVSTNIDQLQKNLAPLVEDVQSKLKGNTEGLQKSLEDLNKQLDQQVEVFRRAVEPLGDKFNMALVQQMEKFRQQLGSDSGDVESHLSFLEKNLREKVSSFMSTLQKKGSPDQPLALPLPEQVQEQVQEQVQPKPLES
What is the function of this protein?
May have a role in chylomicrons and VLDL secretion and catabolism.  Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT.  Apoa-IV is a major component of HDL and chylomicrons.
What are the official names of this protein?
Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: HFQ_FRATN
Sequence: MSRISSLQDPFLNALRKEKVSVSVYLVNGIKLQGQVEAFDQFCIVLRNTVNQMVYKHAISTIVPAKSVRMVYSSFNPYHQNSNDEQDENVDDIHSDDLEIQENEGNIHE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RIPX_CUCPE
Sequence: NVRFDLSGATSSSYKTFIKN
What are the official names of this protein?
Ribosome-inactivating protein, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: Y1434_ARCFU
Sequence: MQPIELAELLTSQAAVLTSLVVIGLILCFIGYKIFRVYSAVIGLFIGQLVGIYITINYYENALIVILASAIVGALLFALIDELGLIVTGAAFGYFVGVYLLPEYQVYAFVLAALFALINLFIEKPLTVLITSVIGASAIALAVHMGITGTHIYDILNDPKKVFDAIFSNAYFDLLWFTLVLTGIITQYVTYKEEREEEE
What are the official names of this protein?
Uncharacterized protein AF_1434.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBT_EUCGG
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKVK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DUT_HELPS
Sequence: MKIKIQKIHPNALIPKYQTEGSSGFDLHAIEEVMIKPHSVGLVKIGICLSLEVGYELQVRTRSGLALNHQVVVLNSPGTVDNDYRGEIKVILANLSDKDFKVQVGDRIAQGVVQKTYKAEFIECEQLDETSRGSGGFGSTGVSKA
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.