PharMolix/UniProtQA huggingface dataset:
Protein: PROA_ECOSE
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLGEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGSVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UFC1_DROPE
Sequence: MVDDSTRKTLSNIPLLQIRAGPREKDVWVQRLKEEYHALIMYVKNNKQSGSDWFRLESNKEGTKWFGKCWYMHNLLKYEFDVEFDIPVTYPTTAPEIALPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGIAHAMALGLAPWLAVEVPDLIEKGIITYKEK
What is the function of this protein?
E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: RLR95_PLAVT
Sequence: MRGASYVAIALFVTVSSQTAAECNQDKPQEGLNNGYVTFSGTIGKMLPRRVLQESRDSKDKSTVHAGAEERMMDPPSEAFKSAIIKTAGVIMTGGEDAIASAAMKTQEKSEALSLGRTSKRRGIDPPTYNVGGQALYALPKPNNNIVSMASDVPIVLANRARVKAPADLINNAARSVSKHDLRLAPPGPSTSSTASFDTEKAFQFDLNKLPDEVEISNSKRQRIDLTPSHVVEQASHALPEPQKYIVTVADSAPNVLARKLGKRDPTLIMQNAASVITKHDFRPAPYGPSSSTVASSVSQIHSQPINQKASKFALNVYPYEVKRLSQETLHPVGHVLHMREENDMFVPSATVNGESVPKDSKTKNTQGPRVHKTDKATGKVEHIHAAFLKAFNLPFHQYPQETAIMIHIVERQVNSPGNRQFVEAFKSLVERLQLPELKIILGTDLEKLLGKESLKELLKKGSLEYQNALKSLREAYYVKLAIMYELFYEFCYVRSDFFDRLVPKVDRTFWILKLSN
What is the function of this protein?
Secreted effector that acts as an elicitor that induces cell death in host plant cells.
What are the official names of this protein?
Secreted RxLR effector protein 95.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: PCP_MYCBT
Sequence: MSKVLVTGFGPYGVTPVNPAQLTAEELDGRTIAGATVISRIVPNTFFESIAAAQQAIAEIEPALVIMLGEYPGRSMITVERLAQNVNDCGRYGLADCAGRVLVGEPTDPAGPVAYHATVPVRAMVLAMRKAGVPADVSDAAGTFVCNHLMYGVLHHLAQKGLPVRAGWIHLPCLPSVAALDHNLGVPSMSVQTAVAGVTAGIEAAIRQSADIREPIPSRLQI
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL361_PAEAT
Sequence: MKVRNSLRALKKIPGAQIVRRRGRTFVINKNNPRMKARQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: URK_STRP6
Sequence: MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBMP_CAMVD
Sequence: MENIEKLLMQEKILMLELDLVRAKISLARANGSSQQGELSLHRETPEKEVAVHSALVTFTPTQVKAIPEQTAPGKESTNPLMASILPKDMNPVQTGTRLAVPSDFLRPHQGIPIPQKSELSSTVVPLRAESGIQHPHINYYVVYNGPHAGIYDDWGCTKAATNGVPGVAHKKFATITEARAAADAYTTRQQTDRLNFIPKGEAQLKPKSFAEALTSPPKQKAHWLTLGTKKPSSDPAPKEISFAPEITMDDFLYLYDLVRKFDGEGDDTMFTTDNEKISLFNFRKNANPQMVREAYAAGLIKTIYPSNNLQEIKYLPKKVKDAVKRFRTNCIKNTEKDIFLKIRSTIPVWTIQGLLHKPRQVIEIGVSKKVIPTESKAMESRIQIEDLTELAVKTGEQFIQSLLRLNDKKKIFVNMVEHDTLVYSKNIKETDSEDQRAIETFQQRVISGNLLGFHCPAICHFIMKTVEKEGGAYKCHHCDKGKAIVQDASADEGTTDKSGPPPTRSIVEKEDVPNTSSKQVD
What is the function of this protein?
Enhances the ribosomal termination-reinitiation event leading to the translation of major open reading frames on the polycistronic viral RNAs.
What are the official names of this protein?
Transactivator/viroplasmin protein, Tav, Inclusion body matrix protein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae viroplasmin family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in cytoplasmic occlusion bodies.
Protein: RPOZ_KOSOT
Sequence: MSVIINYDKLLKRIRHKYAIPIAAARRAEGLKDFGRPKLDPQMVKQAGDKINIALKELEEGRIVIRNEEMLKILVPKVK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL30_BRAHW
Sequence: MAKVVITLVKSPIGYEKSQRATVVALGFKKGKRVVEKEATPQINGMINKISHLLKVEYK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GTAE_DICDI
Sequence: MDYQLHEGKQISQEFPTDISTTKSSDLKSRKTDSPSIQRTHEFVNFSVFPIVNTNEIMNVDIKHFSPDLKCPTSPNIFLQPLTTTPNTTPNTSTTIDSNTEINPIEIQLQSPLLFQPEHLSPQTLKTTIPTFSIPTYPTPLNTKFQSSPPPPPPPPAATTTTTITTTTTTSAGNSTTKNNNNNNNNNNNNNGKSPKQFQDVLIPVTSSGKDGALYTVLENVPIKRTHRRRSANIDKDSLKCYQCNTSNTPEWRKGPEGPATLCNACGLAYAKKQKLTKNNIKFNQSTNVNNNTNNTITQLNQQINNQGLPNLTSTTTTSNNTAAAVNITTPSKRNNKYNTHRSKVFGEVAPSIVYTNGTLNNVGTPVSDTKKSHTFHEYMTPSNSFFTGKPIKTTKTKPKPKSKSKPGKITHTKHEQPQLNEQVQAIMEKNNLLSSSGGSGGAGSSSSSCGTSLNSSLGSSSGTITNSGGGSSGGGGGNLFSNQQLGFTCINNNVSNNNSNNNINNNDKQIQQQIQQVQQQVHQQVQQQLQQQQQVQQQQQQINQEPFLNQQNHYYQNIFQNVSTGNQNCAINTNGGFPQFESPMDIFPYNNNTTNCTQDSNGFVPNLANFEMQGNVLYNSSGSPSSLGQYVIQNNSFSGPNDQNPYVPSVSLNSNKTTNIKNNNNNKKNSKNKNNKNNKNNNNNTKINNHHINNNKNNVNTNQTIIKENNSQKQHQQQQQQQQQQQEQQKQQQEQQKQQEEQQQNLSINNSNQTNENEILGTTTTTTTSTATIITSQVPMNLSPNSDDNQSSSNYSTLSDSGSSPTDSFSGLSVNTPHPNCDSFSSSINNGSNCGSDIETIESPLQMSTDVLTINNCSSNRTTATNNNINNNNNNNNNNNNNNNKCSIKDDTFNLLTNSNLDSFGIIDCINGSSTNTNSFFMETPLLINDEDLLSSSNLTSSSELLPHSFV
What are the official names of this protein?
GATA zinc finger domain-containing protein 5.
Protein: HECW1_MOUSE
Sequence: MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNIDIRNGAHDAITIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIGEVSSENFLDYKNRGVNGSHRGQIIWKIDASSYFVESETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKGIGSEETAQSQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSTIIGNTVNPIWQAEHFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHADDEEISLSAEPESSAETQDSIMNSMVGNSNGEPSGDATEFCKDAKPESPSEGNGVNSSENQNQEHAGPVEEAAGAMEARDGSNVSEAPEEPGELQDPEQHDTQPTLSAEEVAEGLPLDEDSPSSLLPEENTALGSKVEEETVPENGAREEEMQKGKDEEEEEEDVSTLEQGEPGLELRVSVRKKSRPCSLPVSELETVIASACGDAETPRTHYIRIHTLLHSMPSAQRGSTTEEEDGLEEESTLKESSEKDGLSEVDTIAADPQSMEDGESDGATLCMAPSDCSGGHFSSLSKGIGAGQDGEAHPSTGSESDSSPQQGADHSCEGCDASCCSPSCYSTSCYSSSCYSSSCYSSSCYNGNNRFASHTRFSSVDSAKISESTVFSSQEDEEEENSAFESVPDSVQSPELDPESTNGAGPWQDELAAPGGNAARSTEGLESPMAGPSNRREGECPILHNSQPISQLPSLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHINRTTTWQRPSMAPTPDGMIRSGSVHQMEQLNRRYQNIQRTMATERAEEDSGNQNSEQIPDGGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKVTLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLELPRGWEIKTDHQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEASEVSRNRGASLLARPGHSLIAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLDKLSCDADLVILLSLFEEEIMSYVPLQSAFHPGYSFSPRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYITFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENYLEWFRFSGRILGLALIHQYLLDAFFTRPFYKGLLKLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALLRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1.
What are the official names of this protein?
E3 ubiquitin-protein ligase HECW1, HECT, C2 and WW domain-containing protein 1, HECT-type E3 ubiquitin transferase HECW1, NEDD4-like E3 ubiquitin-protein ligase 1, mNEDL1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_NITEU
Sequence: MKTFSAKPHEVRHEWFVVDATDKVLGRLAAAIAHRLRGKHKPIYTPHVDTGDYIVVINADKLRVTGNKAEDKKYYRHSGYPGGIYETTFKKMHERFPTRPLEKAVKGMLPKGPLGYAMIKKLKIYAGDTHPHAAQQPQPLEINA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ARGDC_IGNH4
Sequence: MKTVELTNGSKKKVEDRIVGRHVYGNLYGVDPAKLWDEEGLKELVREAAEVANMKLVEVRSWKFTGYHGGVSVMALVLESHITIHTWPDYEYATVDVYTCGERSDPWRAFELIVERLEPEDYVVHYSDRSSPKRPLGGTAGRIQ
What is the function of this protein?
Specifically catalyzes the decarboxylation of L-arginine to agmatine.  Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity.
What are the official names of this protein?
Arginine decarboxylase proenzyme, ADC, ArgDC, Pyruvoyl-dependent arginine decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: JBP1_LEITA
Sequence: MEPDSKKVKLDIFNFPTTRETRTPEEVAESYAEAVKSHPFYDNVHSVVDFYDSGTIKDGRGQIIGVVLREALPKYAASMASELLTSAAVRTSLRSMMFGGEPPLSGIAGYFDYRGSPVELKSRKTSFTYEHEAAWPAVFPVVDYVSEIYRHVAPERWKAQNDAIPDLVRIHGTPFSTLTINSRFRTASHTDVGDFDAGYSCIACLDGQFKGLALSFDDFGINVLLQPRDVMIFDSHHFHSNTEVELSFSGEDWKRLTCVFYYRAALGEPASYAEYQRRLEKSKTDTRFTPVVHHVRVKENGTSVNRPSPVYPISQSPFWVPMVAHCLQHCASAAQCVHEAMTADGSRLAEMMFGESLSTSDGIPLRGEDEKVKANGDSTPRPLSRLGGFSETNLMVSTAVEKKKYLDSEFLLHCISAQLLDMWKQARARWLELVGKEWAHMLALNPERKDFLWKNQSEMNSAFFDLCEVGKQVMLGLLGKEVALPKEEQAFWIMYAVHLSAACAEELHMPEVAMSLRKLNVKLKDFNFGGTRYFKDMPPEEKKRRMERKQRIEEARRHGMPSGSHEKRANWLTNDSFDYQTEDCVIDYAQHKWVLPALHAKEVTKTVRTGELPTTERVVRVLVVIPDPQSKLENVDCKLEVPDMVGSSSEWERLMSSPAVHRVLSAAQRNLQLPDSVTHGNVQTHFAFHSTLPTDIYDFVVLQHVLSRIPDDAQASAYIRRAAALCSGCLFVVETDVQCRQYYTLKYSIRCSYDTVAPLFFQQLHRVCYGTKTARVRTKGELESLIPTVCCARYKLQGSPLNTTVHVVSPFPSCEVQNLSSALCDRA
What is the function of this protein?
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU).  DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation.  Also specifically binds to base J-containing DNA (J-DNA).  Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis.  Thymine dioxygenase activity and J-DNA-binding are independent functions.
What are the official names of this protein?
Thymine dioxygenase JBP1, J-binding protein 1, Thymidine hydroxylase JBP1.
What is the protein family that this protein belongs to?
Belongs to the TET family. JBP1 subfamily.
Protein: CAS1A_FRATN
Sequence: MKHLIISEYGIYLGLESGRLVVKNKDDKKYFPLNRLATLSIAKKGVSFSSDLVEQFSLRGIKLFFLDFRGVAHSMLVGANQHAVVQARINQYRYIDRNALTLSIKLIAAKIKNQRATLNYFNKHHKSINLLNAIEELKRVAQLIKNAKTLNDVLGYEGYAANIYFSSLAKDKFLSASFANREGRGSQEIANSMLNFGYAILSSYILNAITNAGLEPYLGFLHQKRPGKMSLVLDLMEEYRAWVVDRVVIKLREQYKNKQYIDTKLKSILISEIQATIAKKYIYNGKKLKLEHIIQRQVYRLSGEFAGEHNYKPYIFKW
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: RL20_ELUMP
Sequence: MRIKFSVARHARKKKVLKRASGYYGDKSRRLRMATQQVDKSLVHAYTGRKDKKHQYRQLWITRINAAVREEGLNYSNFINGLAKSNITLNRKMLSEMAIQDPLSFKKLVDVAKQAIAK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ISPH_SHIF8
Sequence: MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKHAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MOAD_HAEIN
Sequence: MLNVLFFAQTRELIGVDAIQLEDDFATAEAVREHLAQKGDKWALALEKGKLLVAINQTLMPLESAVKNGDEIAFFPPVTGG
What is the function of this protein?
Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, MPT synthase subunit 1, Molybdenum cofactor biosynthesis protein D, Molybdopterin-converting factor small subunit, Molybdopterin-converting factor subunit 1, Sulfur carrier protein MoaD.
What is the protein family that this protein belongs to?
Belongs to the MoaD family.
Protein: ZN207_PONAB
Sequence: MGRKKKKQLKPWCWYCNRDFDDEKILTQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMDEGRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKAPFPSTAQAQVAVQGPVGTDFKPLNSTPATSTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY
What is the function of this protein?
Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly.  ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets.  Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks.  Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3.  Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3.  According to another report, the stabilization is independent of the proteasome.
What are the official names of this protein?
BUB3-interacting and GLEBS motif-containing protein ZNF207, BuGZ, Zinc finger protein 207.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes primarily to the nucleus in interphase, concentrates at kinetochores prior to nuclear envelope breakdown and during early prometaphase, and disappears from kinetochores upon microtubule- binding.
Protein: CYAY_YERE8
Sequence: MNDSEFHQLADQLMLCIEETLDGFSGDSDIDYETNGGVMTLTFENGSKIVINRQEPLHQVWLATKAGGYHFDYREGHWYCSRSGEEFFTKLSEAATAQAGEVVSFS
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: TRUA_RHOBA
Sequence: MQANDRPRTFHLTVAYDGTEYCGWQVQPEQRSIQSELERVIRPLAGRPVRVLGSGRTDAGVHAIGQVARCVLPVWKADTVALQRAINSKLPNDIRVKAVRETRERFHPIADATGKQYQYLVQVGGSRDPFANRFVNRVGGPIDHSAMQSAAAKFVGRHDFKAFQGTGAERPSTVRTIHSARWIPRVATGPTGAELEGEHWCFEIDGEGFLYNMVRNLMGTMLEVGRGKKSPNWIDEVLASRDRKMAGPTAPPQGLFLCRVDYPDEVFQVEEPDVIE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PURA_MYCSJ
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELRGLEERGVDTERLLISADAHLLMPYHVAIDKVVERYAGSKKIGTTGRGIGPCYQDKIARQGIRVADVLDPTVLAEKIEGALELKNQVLVKIYNRKALEPAEVVENLLEQAEGFKHRIADARLLLNQALERDEIVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGASVGSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPICVGYTIDGKRTDEMPMTQSDIARAEPVYEELPGWWEDISGAREFDDLPAKARDYVLRLEELAGAHVSCIGVGPGRDQTIVRRDVLAPS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_MARMS
Sequence: MANISTSEMRSGSKVMVDGDPCAIIDNEHVKPGKGQAFNRIKLRNLKTGRVWERTFKSGDTLETADVMDTDMEYLYTDGEFWHFMAVDGSFEQHAADETAVGDTIKWLKEQEKYVVTLYNGAPLAVAAPNFIELEVKETDPGVKGDTANGGSKPAFLVTGAMVRVPLFINIGEVLRVDTRTGEYVSRATGK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_LEGJE
Sequence: MAKELRFGDDARQQMLAGVNALADRVKATMGPSGRNVVLERSFGAPTVTKDGVSVAKEIEFENRFKNMGAQMVKEVAAKTSDTAGDGTTTATVLARSIVVEGHKAVAAGMNPMDLKRGIDKAVTAITKELQKMSKPCKDGKAIAQVGTISANSDQAIGSIIAEAMEKVGKEGVITVEDGNGLENELSVVEGMQFDRGYISPYFINNQQNMSAELEHPFILLVDKKIATIRDMLSVLEAVAKSGRPLLIVAEDVEGEALATLVVNNMRGIVKVCAVKAPGFGDRRKAMLQDIAILTNGQVISEEIGTSLETASLESLGTAKRIVVTKENTTIIDGEGKATEINARIAQIRAQMEETSSDYDREKLQERVAKLAGGVAVIKVGAATEIEMKEKKARVEDALHATRAAVEEGIVAGGGVALIRAQKVLDGLKGDNADQDMGINILRRAIESPLRQIVANAGYESSVIVNKVAEHKDNFGFNAATGQYGDMVEMGILDPTKVTRTALQNAASVRSLMLTTECMVADLPKKDEGMAGAGDMGGMGGMGGMGGMGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRTP1_MOUSE
Sequence: MDPAERAQAARARVPRIDPYGFERPEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGNGGVRKSVTVKRYVRKGIPLEHRARVWMAVSGAQARMDQSPGYYHRLLEGESSSSLDEAIRTDLNRTFPDNVMFRKTADPCLQKTLYNVLLAYGLHNPDVGYCQCCAQKPGSSAGLRSSLTGMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDGHGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEASSIPDICDKFKQITKGDFVTECHAFMQKIFSEPGSLSMTTITRLRKSCRAALQAQS
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s).
What are the official names of this protein?
Growth hormone-regulated TBC protein 1, TBC1 domain family member 6.
Protein: CO1A1_EQUSP
Sequence: GPMGPSGPRGIPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGIPGTAGIPGMKGFSGIDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGIPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGNKGDTGAKGEPGPTGIQGPPGPAGEEGKRGEPGPIGIPGPPGERGFPGADGVAGPKGPAGERGAPGPAGPKGSPGEAGRPGEAGIPGAKGITGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGIPGPAGPPGESGKPGEQGVPGDIGAPGPSGARGFPGERGVQGPPGPAGPRSQGAPGIQGMPGERGAAGIPGPKGDRGDAGPKGITGPIGPPGPAGAPGDKGETGPSGPAGPTGARRGEPGPPGPAGFAGPPGADGQPGAKGDAGPPGPAGPAGPPGPIGSVGAPGPKGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKGPRGETGPAGRPGEAGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGIPGQRGFPGIPGPSGEPGKQGPSGASGERGPPGPVGPPGIAGPPGESGREGSPGAEGSAGRDGSPGPKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGEAGPAGPAGPIGPVGARGPAGPQGPRGFSGIQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGINGIPGPIGPPGPR
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.