PharMolix/UniProtQA huggingface dataset:
Protein: MNHF1_STAHJ
Sequence: MLKIIMIIALIVVAISMLAMFVRIIKGPTLADRILALDAIGLQLMACIALYSIFIGSEYLLVAILLIGILAFLGTAVFSKYMDKGKVIERDNEHHH
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F1, Mnh complex subunit F1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFA_GRAFK
Sequence: MIDKIKGHIADVESFNAKTKDEIEAFRIKYLGKKGILNDFFAEFKNVPNEQKKEFGQVINELKTAAQVKVNALKEDLENNQEEKGVYGDLSRPAEPVEIGARHPISIVKNQITEIFSNIGFNVSEGPEMEDDWHNFTALNLPEYHPARDMQDTFFIQTDPDILLRTHTSSVQVRYMEENKPPIRTISPGRVFRNEAISARSHCIFHQVEGLYIDKDVSFADMKQTILYFTEQLFGKSKIRLRPSYFPFTEPSAEVDVYWGLETETDYRITKGTGWLEIMGCGMVDPNVLRNCNIDPKEYSGFAFGMGIERIAMLLYQIEDIRMFYENDLRFLEQFKSAL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_JANMA
Sequence: MAHKKGGGTTRNGRDSESKRLGVKVYGGQAINAGGIIVRQRGTKMHPGENVGIGKDHTLFALTDGKVAFVTKGALQRHYVTVVPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: HSLU_CERS5
Sequence: MTDLTPREIVSELDRFIIGQKDAKRAVAVALRNRWRRKQLSDDIRDEVYPKNILMIGPTGVGKTEISRRLARLAKAPFLKVEATKFTEVGYVGRDVDSIIRDLVDAAIVETRARMREDVKSRAVKAAEDRVIEAIAGRDAREQTREMFRGKLKRGELDATVIEVEVADTSNPMQMLDPTGQGQMGMMNLGEIFGKAFGGRTTRRKMTVAESHDILMNEEADKLLDDEVVKATALEAVQENGIVFIDEIDKVCARSDMRGADVSREGVQRDLLPLIEGTTVSTKYGPVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELRALTEEDFVRILSETDNALTRQYKALMKTEKVGITFTEEGIKALASIAAEVNRSVENIGARRLYTVMERVFEELSFHAPDRSGEEVTVDAAYVEKNLGELARSTDLSRYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_SHIBS
Sequence: MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVNPKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAPSAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTIYHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRGALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGHMEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLERKVNQQD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RLME_FRATN
Sequence: MSKGSSTKKWLHEHTSDYYVIQANKLGYRSRASFKILEIQNKYQLFKPNMFVVDLGAAPGGWSEQVIKYIGKNGKLIALDLLEMAPIAGVEFIQGDFSSDETYQKLNTLVNNQKIDCVISDMAPNLSGNKTSDQAKSIYLLELALDFANTNLNKNGSFVAKVFQGQGSDEYLKLVRESFNKVIQFKPKSSRAKSREFYVIATEFKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y002_METJA
Sequence: MEIFMEVPIFVVISGSDLYGIPNPSDVDIRGAHILDRELFIKNCLYKSKEEEVINKMFGKCDFVSFELGKFLRELLKPNANFIEIALSDKVLYSSKYHEDVKGIAYNCICKKLYHHWKGFAKPLQKLCEKESYNNPKTLLYILRAYYQGILCLESGEFKSDFSSFRCLDCYDEDIVSYLFECKVNKKPVDESYKKKIKSYFYELGVLLDESYKNSNLIDEPSETAKIKAIELYKKLYFEDVRE
What are the official names of this protein?
Uncharacterized protein MJ0002.
Protein: ERT1_DEBHA
Sequence: MSEIKNEPMSNSDSVASSNSAKMRRKKTNRACNHCHKAHMTCDTNRPCQRCLQRGLESSCQDAPRKRKKYLADVPPNVLSRHDGLSQSPPYEMGKNDTINYQSGPFQERPPSSEFNPPMPTANTDNDINQDFGAFGVYPNSHLFPSNTNQTNQDAGADMSHSQGQSKPPINQHMHQQGLPSYNKPRRTNFLSSAADLEYSTLSSILQDNFVHVNNNTSAEGTPNSLNLSPSVLPNNAPNTNITDSRNTTSSNSLNNYGQQNKPMNYTSGSSHASSPNDSIFNSKQMSSINGINKNKYYYSSKYPKCDESINQYFLGPTGSDHELIYPDVITAIEEMKALDPAVYHERNSKSSLSFTIGIIPESNEYTKGRKPQENKETFKEPDEIYAKVNKPFSYTPGYHSLIAYLRKRFPKEMLVKMAESIAAYRPSFIACTNSLKESDLIFMEQCFQRTLLTYDNFIRVSGTPTIVWRRTGEIAYVGNEFCVLTGWKKEDLLLNTKKFIVELLDDKSVVEYFQLFSKIAFGDFLGATMTECTLLTPKKDVKIRTGCMWTLKRDVFGIPMMIIGNFLPII
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis ERT1.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSCL_BARHE
Sequence: MLKEFKEFALKGNMIDLAIGVIIGGAFGGLVNSIVNDIFMPIIGLITGGIDFSNMFIQLAGEKQATLSAAKAAGATISYGNFITLLINFLIIAWVLFLFVKSMNKIRRKQEEEETSKKMSLEQQLLSEIRDLLAKKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL4_CLOPE
Sequence: MPKVGLFNKEGQQVGDIQLNEQVFGVEVNKYALHQVVVAQLANKRQGTQSAKTRSEVRGGGIKPWRQKGTGRARQGSIRAPQWIKGGVVFAPKPRDYRMSIPKSMRKVAMTSALTSKVADMVVLEDLTFEAPKTKEAVKMLNAFEAKKTLIITAEVNENVYKSARNIRGVTVMPVNNINVYDLLNCKTLMITKEAVNKIEEVYA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PURA_HYDCU
Sequence: MVKKNIVVVGTQWGDEGKGKIVDLLTDRVAAVVRFQGGHNAGHTLVIDGKKTVLHLIPSGILREDVECFIGNGVVLAPEALEKEVAQLEDTGLKVKHRLKISDACPLILDYHVALDQARELARGNKAIGTTGRGIGPAYEDKVARRGLRAGDLKNMSQLKQKLQTAMEYHNYMLTNYYKAEPVDFETLWAKCQAYADLIVPMLADIPNLIDLYNKEGKNLMFEGAQGTLLDIDQGTYPYVTSSNTTAGGAASGSGIGPCQLDYVLGITKAYATRVGGGPFPTELRYDVATDEGDAVGKELGTRGREFGATTGRQRRCGWFDAVALRRSAQVNGLTGVCLTKLDVLDELEEIKVCTKYRKDGQDVFLPPSSADEYELVEPHYETLKGWNTSTVGIDSWDALPEEAKVYIRFLEKEMGVTVSILSTGPDRSETLVLEDPFEV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEKT_CHLRE
Sequence: MPSYNHTSNGVNMANFRALGGKNTGRGGTYRAPYEWTLESVEQMGLGATENRMSSTLRDASSQLQAVASATVANDISIVDRALTTKLSQTESLKNMLETCLAEVISEIAELLSTKKRLEERNGKVQAKIGVNSNRMQVRSSRPPREMTMDEVEKGLIKQQGMLGSFSDRVARAVAQVDREVAQLEAVRAKLEADLRDKTEALRVDEAVLSIPTDPTVEGTLSPTFRRGAADCPPKTPHTWVRNTEDNLRNAHHWLADSARLRKAIAHAVANSRATEHDVANRLNENMLAKVAATRNLREDLQAQLEKVREEQARAKGQRSALTSALDDKRGPLAQARERLAVRKARPCRENVNDEVEAALAKEVAHLAAVTQQLSVKVAAVDREIAALDATAAQLESNIADKDDALRVDERVVLLDGRINLAQRPPSSVASFAMSDMSAPRTQTLARIRELEASLTSARREREAMESSIRQLRDTMGGGGAF
What is the function of this protein?
Structural component of ciliary and flagellar microtubules.  Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in flagella and cilia.  Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
What are the official names of this protein?
Tektin.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body.
Protein: DAPH_CLONN
Sequence: MNYDLTNPYEIARYIKESKKSTPLKVYVDGNLTNCNVNNIECYGENNFYVLFGESQEILNFLDENKDSINKYRIEQDRRNSAIPMLDTKNIDARIEPGAIIRDMVSIGKNAVIMMGAVINIGCEIGEGTMVDMNAVLGARAKLGKNVHLGAGAVVAGVLEPPSKSPCVIEDNVLIGANAVILEGVRVGKNSVVAAGSVVVEDIPENVVVAGSPAKIIKTVDDKTKDKTKLMDDLRK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: TREA_SHIFL
Sequence: MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILLGPLFNDVQNVKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDNYFTMLGLAESGHWDKVADMVANFAHEINTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDSTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYLWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATHPTVKSATTQPSTKEAQPTP
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: F16PA_PSYIN
Sequence: MITLGEYIIKKQHESPEATGELSSILGAIRLATKVVNRDINKAGLVDIIGATGVENVQGEVQQKMDLYANDVFKAALEARGEVCGVASEEEDEFVSFNDQRCINSKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRISEPGKPAILEDFLQPGTEQVAAGYVIYGSSTMLVYTTGYGTHGFTCDPSLGTFYLSHENMKIPDNGSIYSINEGNYLKFPQGVKKYLKYCQEIDGPTNRPYTSRYIGSLVSDFHRNLLKGGIYIYPSTASAPKGKLRLLYECNPMAFIMEQAGGRATDGFNRRIMELTPTELHQRVPFFCGSSKMVDKVEAMMEEYSSEEK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XOAT8_ORYSJ
Sequence: MVQLPAMKRVKGRAPLSVVVAIIGGLALAGIIFTEDLRGLTEVKEKVTDKEKKRTSLRTVMRTSALLSADQPPPPAVLSVEPATATPPPAPKMAFNATRCSVTDGYWAYDRSKKLPYTDQTCPYVDRQDSCQRNGRPDSDYLYWDWHLDDCLLPRFDPVSMLEKLRGKRIMFVGDSLQLGQWLSFVCLVNSAVPDTPGAKSMERSRTLSVYTVKEYNASIEFYWAPFLVESNSDRNIALGAGGRVLHVDAIEEHGKHWRRADILVFDSYVWWMTGYRIKSVWGSFGDDGYEELDAWVAYRLGLKTWANWVDSNVDPATTRVFFMSISTTHMRSEDWGREGGIRCYNETWPITQRGYRGSGSDRRMMEVMSDVLGRMRTPVTLLNITQLTEHRVDAHVSVYTETGGLLVTDEEKTDPQRYTDCIHWCIPGVPDTWNRLLYAHL
What is the function of this protein?
Probable xylan acetyltransferase required for 2-O- and 3-O-monoacetylation of xylosyl residues in xylan (PubMed:29569182).  Possesses extremely low activity in vitro (PubMed:29569182).
What are the official names of this protein?
Probable xylan O-acetyltransferase 8, Protein trichome birefringence-like 8, OsTBL8.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: ERPA_BUCAT
Sequence: MENAFKSHLQFTEKAIKKIKNLIEIEKNHDLKLRIYINGGGCSGFQYQFIFDTSINEDDIIITQSEVSLIIDPISLQYLYGGQIDYLENLEGSKFIVSNPNAKNTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: UXAC_ECOLU
Sequence: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDRILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RS7_BIFLD
Sequence: MSRKGPSKKHVVLPDPIYGSTVVAQLINKILLDGKKSIAEDIVYSALDMVKEKSDQEPVAVLKRALDNIRPSLEVRSRRVGGATYQVPVEVKPNRANTLSLRWLTDFSRARREKTMAERLANEILDASNGLGASVKRREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ENGB_BARQU
Sequence: MTKYSSLSGIFSRKWIFIRGIPTIHFLPPEGPPEIAFAGRSNVGKSSLINALVQQKSLARTSNTPGRTQELNYFVPDGFSGEPGNLPPIALVDMPGYGFAEAPKNLVDAWTHLIFSYLRGRTTLKRVYVLIDSRHGIKKNDGDVLDLLDKAAVSYQIVLTKSDKTKSNELAKLIMITKTKLLKHPAAYPELLVTSSEKALGLEELRAAILQAIAV
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CMOA_SALSV
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNTQVYDLGCSLGAATLSVRRNIRHEHCRIIAVDNSPAMIERCRRHIDAYKAPTPVEVVEGDIRDITIENASMVVLNFTLQFLEPAERQALLDKIYLGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLRKAGFEHSELWFQCFNFGSLVALKAGVAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RF1_CHLCH
Sequence: MLDKLQAIKEKHLDLEQALSDPSLANDQERFRKLNREYSNLREVVQAFDAYQRKATELEAAQHLLATESDTEMKALAEAEVDELQETVAELEQGLKILLLPKEEADSRNVIIEIRAGTGGDEASLFAADLTRMYQRYAEQKGWQYKVLDYNESSVPGGFKEMILEISGNNVFGTMKYESGVHRVQRVPDTEAQGRIHTSAVSVAVLPEAEEVDVEIRRDDLRFDTYRSGGKGGQNVNKVETAVRITHMPTGIVAACQEERSQLQNKERAMQMLRTKLYDIQLAEQQQQRADLRRTMVATGDRSAKIRTYNYPQSRVTDHRIGFTSHALPQIMQGELHEVIEALIMHDQAERLKSELQ
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX96_HOTJU
Sequence: VGCEECPAHCKGKNAKPTCDDGVCNCNV
What is the function of this protein?
Calcium channel activator.  Rapidly and reversibly activates ryanodine receptor 1 (RYR1).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 9.6, BjTx-1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 09 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AP1_ASPFU
Sequence: MADYNTLYQQGLYLSPDQQDLLLAALSSNNPTQKQQTVTHNSEANQNLNHTPGHASSGSFSVSPPSGLDGSVNQSTTFGYEDSPYLDLNPDFDLDFLGNESLIGDLPPSLPSTEDYEPGDKRKDIDGQVNDKEDSGKKRRESDEKAAKKPGRKPLTSEPTSKRKAQNRAAQRAFRERKEKHLKDLEAKVEELQKASDNANQENGLLRAQVERLQLELKEYRKRLSWVTSTSGLSPVNAIPGAYSKGMYGLNNNEFMFDFPKFGDLPGSHLFTNTQTSKSNQNKAKDNPTATPRSEAQVPGVLNRNDLKISSPNGLSNGPSPAKSTPSGQTPNSQTSTRPGSGTLNGAVDNNGAARGYQVNSSYSASTKQATHDTPSSDSPSSSSDSHQSQLLSSNGTSPEPSLHSPAVKATESSTPHACTYTTINGEESFCAQLSMACGNINNPIPAVRQNSESASNTPSHANSSDKALGLDFFAQQNGGQFDPVLFGDWREPQDAILSQDFGTFFDDAFPLPDLGSPSHNFSEATKQPAAPKKDLIAEIDSKLDEDEEVVPGEDKSQMLTCNKIWDRLQSMEKFRNGEIDVDNLCSELRTKARCSEGGVVVNQKDVEDIMGRVK
What is the function of this protein?
Transcription activator involved in oxidative stress response and redox homeostasis (PubMed:17921349, PubMed:18608886, PubMed:18651311, PubMed:20376564, PubMed:27748436).  Regulates the transcription of genes encoding antioxidant enzymes and components of the cellular thiol-reducing pathways, including thioredoxin peroxidase (aspF3), cytochrome peroxidase, and the protein AFUA_3G00730, which appears to belong to the glutathione S-transferase family (PubMed:17921349, PubMed:18651311).  Proteins of the protein degradation pathway are also regulated by yap1, as well the p-nitroreductase family protein AFUA_5G09910 (PubMed:17921349).  May be involved in antifungal resistance to voriconazole (PubMed:20376564).
What are the official names of this protein?
AP-1-like transcription factor yap1, BZIP domain-containing transcription factor yap1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. YAP subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The nuclear localization is oxidative stress-dependent and oxidized yap1 is found predominantly in the nucleus, while reduced yap1 is continuously exported to the cytoplasm.
Protein: HOA_STRTE
Sequence: MSQEAARDAAAGRPVQIHDPTLRDGQHAVRHSLGAEQFRAYLKAADAAAVPVVEVGHGNGLAASSLQVGRARLSDDEMMSIARETLTTSKLGVLMFPGWATTQDIKNALAYEVDLVRIATHCTEASVAERHLGFLRDEGVEAHGMVVMTHMASPDQLAEECARLVGYGATGVGILDSSGHFLPSDVTARIGAICAAVDVPVMFHGHNNLGMAVANSIAAAQAGAGILDACARGFGAGAGNTQLEVLVPVLERLGFRTGIDLYRLLDAADIAGRELMPAPPTIDSVSIVSGLAGVFSGFKKPVLDIAAREGVDPRDIFFELGRRQVVAGQEDLIVEVALALRAARDGASPASSGTGPC
What is the function of this protein?
Involved in the biosynthesis of the peptidyl nucleoside antibiotic nikkomycin.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: HKR1_YEAST
Sequence: MVSLKIKKILLLVSLLNAIEAYSNDTIYSTSYNNGIESTPSYSTSAISSTGSSNKENAITSSSETTTMAGQYGESGSTTIMDEQETGTSSQYISVTTTTQTSDTMSSVKKSTEIATPSSSIVPTPLQSYSDESQISQTLSHNPKSVAESDSDTTSSESSSSVIISTSDSSAVPREISPIITTDSQISKEEGTLAQTSSISETTRIAQMVTRVSQISSITAASTIDGFSSESTQTDFSNTVSFENSVEEEYAMSKSQLSESYSSSSTVYSGGESTADKTSSSPITSFSSSYSQTTSTETSESSRVAVGVSRPSSITQTTSIDSFSMSEVELSTYYDLSAGNYPDQELIVDRPATSSTAETSSEASQGVSRESNTFAVSSISTTNFIVSSASDTVVSTSSTNTVPYSSVHSTFVHATSSSTYISSSLYSSPSLSASVSSHFGVAPFPSAYISFSSVPVAVSSTYTSSPSASVVVPSAYASSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPVAISSTYTSSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSALVVLSSTSTSSPYDIVYSPSTFAAISSGYTPSPSASVAMSSTSSSSPYDIVYSLSSSASRSSIATYEFSPSPSTSLPTSSTYTYFSSAYAFEFSSERYSTTSTIAPTQIHSTLSRITDFLLQTSMAIQSIVSQQISTSSTLNDEIHSSALSVFNPSASNLVETSLIISSTQASITSPKNSAKISSLQSQLSSSTKNPYDTANKNTETSGRSTVVSNFLYTSSAAKPDNEKFSATPTEITTISSSSHAYSLSIPSSHNSVTGLSHNFVDSSKSATSFGYSSSSISSIKLSKETIPASKSVSNTQERITSFTSTLRANSQSEKSEGRNSVGSLQSSHISSNPSLSTNTKVDSKSLSRKVSKTMGENGEETGLTTTKTQYKSSSETSGSYSRSFTKISIGPATTAVQTQASTNSVFTAPALSTYPTTPYPSPNSYAWLPTAIIVESSETGPTTASFNPSITGSLPNAIEPAVAVSEPINHTLITIGFTAALNYVFLVQNPLSSAQIFNFLPLVLKYPFSNTSSELDNSIGELSTFILSYRSGSSTTTLSPKSISSLSVVKKKKNQQKKNATKSTEDLHPPQVDTSSIAVKKIVPMVDSSKAYIVSVAEVYFPTEAVTYLQQLILDENSTLYSNPQTPLRSLAGLIDSGIPLGGLTLYGSGDGGYVPSLTSSSVLDSSKGNSQNIDGTYKYGALDDFINSFTDSASAGKYAVKIIIFLIVLTIGVLLWLFVAFFAFRHRNILLKRHPRNCIGKSLNNERELESTELSRSSSGNQVYNEKPPESENESVYSAVDDHYIVTGENTVYNTIHRLHYTINDDGDLLYRDAIPLDFDQTNGDDGSGIDSIVRDCVYDKNQDATEAFLNDEESISGILDVDENGDIRLYDSYSDNEESNSFHLPDEVIENYNKNHLCETKLHGLGTESCTTDDPDTGNQITNEFSTGSQTCLPSTAYTTPLHTNSIKLHTLRYTESSLPKPNQTLFSNLEDLEIEDIDDNGSVSDVHIEELDALDEELYKRMSKVIKQQNHQTTKI
What is the function of this protein?
Plasma membrane signaling mucin that promotes activation of the MAPK for the filamentous growth pathway.  May regulate beta-glucan synthesis.  Overexpression provides resistance to HM-1 killer toxin.
What are the official names of this protein?
Signaling mucin HKR1, Hansenula MRAKII killer toxin-resistant protein 1.
What is the protein family that this protein belongs to?
Belongs to the HKR1/MSB2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL18_SYNSC
Sequence: MSQISRKQQTQKRHRRLRRHITGTSDRPRLAVFRSNNHIYAQVIDDAAQSTLCSASTVDKELRTGLKAPAGSCDASVAVGELVAKRAMAKGIQQVVFDRGGNLYHGRIKALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ODO1_BRUAB
Sequence: MAKQEQAPDRANDVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTRKNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSVRAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNVLGLEYATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVLSQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLEIVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGLKGHRVAGTLHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAKVATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEGLVTQDDIDRMKADWRQKLEGEFEAGQSYKPNKADWLDGAWAGLRTADNADEQRRGKTAVPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGEGIDWATAESLAFGSLAVEGHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGYEYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGPEHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRAISTLAELSGESSFHRLLWDDARYNKDKGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGIDDVYLLRVEQLYPFPAKALINELSRFRHAEMVWCQEEPKNMGAWSFIDPYLEWVLAHIDAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDALG
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: RL34_COREF
Sequence: MAKGKRTFQPNNRRRARVHGFRTRMRTRAGRAIVAARRRKGREKLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.