PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_YERE8
Sequence: MIEADRLISAGVISDEESIDRAIRPKLLAEYVGQPHVREQMEIFIQAAKQRGDALDHVLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVADLEHIVSRSAKCLGLELTPEGAHQLARRSRGTPRITNRLLRRVRDFAEVRADGAINGDVAMKALDMLNVDAEGFDFMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIATNHAYKHFGITREE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: FAD3D_ARATH
Sequence: MASSVLSECGFRPLPRFYPKHTTSFASNPKPTFKFNPPLKPPSSLLNSRYGFYSKTRNWALNVATPLTTLQSPSEEDTERFDPGAPPPFNLADIRAAIPKHCWVKNPWMSMSYVVRDVAIVFGLAAVAAYFNNWLLWPLYWFAQGTMFWALFVLGHDCGHGSFSNDPRLNSVAGHLLHSSILVPYHGWRISHRTHHQNHGHVENDESWHPLPESIYKNLEKTTQMFRFTLPFPMLAYPFYLWNRSPGKQGSHYHPDSDLFLPKEKKDVLTSTACWTAMAALLVCLNFVMGPIQMLKLYGIPYWIFVMWLDFVTYLHHHGHEDKLPWYRGKEWSYLRGGLTTLDRDYGWINNIHHDIGTHVIHHLFPQIPHYHLVEATEAAKPVLGKYYREPKNSGPLPLHLLGSLIKSMKQDHFVSDTGDVVYYEADPKLNGQRT
What is the function of this protein?
Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes.  It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol.
What are the official names of this protein?
Temperature-sensitive sn-2 acyl-lipid omega-3 desaturase (ferredoxin), chloroplastic, Temperature-sensitive omega-3 fatty acid desaturase 8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: MDM34_COPC7
Sequence: MLAAKQPLVVPMHLRLSHFRLSSYVVLVVSKQKGITIVFKTDPLQNVDINSTFDSIAVIQSFIQREIEGQLRQMFREDLPSIIHRLSQQWVKAKVETPYKKQNQDSLQKAPPPTPTEPVPRPLGISRSRSAGHALETMSTPDLSAPQFDRRRTAASDIHGPAFLRPPLATAPRRPQSTTGISVAGRGSPLSAPPITHPTNSSTSTITSTSTAAEPSTFPDLEHFDPTYGLRPEGLPTKPVFKGFSKLFAPNKGLADLAEEISSQSSSVADGDSDYLSSGSATDEEEYERNSYDFVEWGSTTGPNTTPPEPVVEYETIPAIGGGTITRPRVVHAQSQIQLPPGVSPVASSPSRNVATVLSRTGSGSNGSRSGAVTPGILSRNPSNPYFADRLAALPHIYRPQNISSGPLSAPPIASSSRRPFSLAGGYDGHEDVKMKQRASYAYSVHEEAVYMQHTGGAVNRYPHPYDLERHRYQSESKYDDEDIEDYSDEEDNGRGPHHYHPRAHRTRHEAHDDYFTSRHPSASVPPSSPPRSSARPPSTIKRRLSVSSNTTNRTSFSASSAYKHHHPNHSSLSLDPSSSISNHPGNDKAKIVLRPSLLNNSIHHLSTLSHSNHTLSPYTRSFEHFAVRSGPPRGSGAASAVVKSGSGSGIPTPSTSGAGGGSGMAGGGIGLASGSGGGSLGRAKGLTTTAGIVGLGAATSRLGKTKADVVPKARRKRVFRIGGKKPEDNSNAAPGETDTRNVSREEYGADEIGEGYVEGLGHASGRAGSQMGKRPRPRHRKKPSYAASGTDFDEADMDRYFKSMHDAEEEATPVPRSKDRRP
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: PVK1_PERVR
Sequence: GSTGLIPFGRP
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, PerVi-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRPH2_RAT
Sequence: MALLKVKFDQKKRVKLAQGLWLMNWLSVLAGIVLFSLGLFLKIELRKRSDVMDNSESHFVPNSLIGVGVLSCVFNSLAGKICYDALDPAKYAKWKPWLKLYLAVCVFFNVILFLVALCCFLLRGSLESTLAYGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQLTNNSAHYSYDHQTEELNLWLRGCRAALLNYYSSLMNSMGVVTLLIWLFEVSITAGLRFLHTALESVSNPEDPECESEGWLLENSVSETWKAFLESFKKLGKSNQVEAEAADAGQAPEAG
What is the function of this protein?
Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity).  Required for the maintenance of retinal outer nuclear layer thickness (By similarity).  Required for the correct development and organization of the photoreceptor inner segment (By similarity).
What are the official names of this protein?
Peripherin-2, Retinal degeneration slow protein.
What is the protein family that this protein belongs to?
Belongs to the PRPH2/ROM1 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.
Protein: SYH_AROAE
Sequence: MTEKKPMIQALQAVRGMNDILPDEAEAWEHFEDIVRDWLRSYGYRPIRMPIVEPTPLFKRAIGEVTDIVEKEMYSFEDALNGEQLTLRPEGTASCVRAAIQHKMLSAGAQRLYYHGPMFRHERPQKGRYRQFHQIGVEALGFDGPDIDAEHILMCARLWDDFGLEDVRLELNSLGSSDERARHRAELVAYLERHRERLDDDGRRRLHTNPLRILDTKNPELQDLVDNAPKLLDFLGEDSLKHFNGVQVLLKDAGVPYRINHRLVRGLDYYNRTVFEWVTTRLGAQGTVCAGGRYDGLVEQLGGRPAPAAGFAMGIERLLALWRESGGEAEPAQPDVYVVHLGEQAQRLAFRAAEALRSHGFAVLMHCGGGSFKSQMKKADASGAPVAVVIGDDEAATGEVGLKPLRGPGGQQRVALDGLANAVAECLFTENEEEDGSL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI_ECOLC
Sequence: MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDFRYRATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSPWMVMQAANSEARKLLSAFAQHN
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADA_PSEPK
Sequence: MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKLLERNGKVDPKEVEDVIWGCVNQTLEQGWNIARMASLMTPIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHMGHVSMMHGVDPNPHLSLHAAKASGMMGLTAEMLGKMHGITREQQDLFGLRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKVFDFDETIRPETTLEGLASLKPAFNPKGGTVTAGTSSQITDGASCMIVMSGQRAMDLGIQPLAVIRSMAVAGVDPAIMGYGPVPSTQKALKRAGLTMADIDFIELNEAFAAQALPVLKDLKVLDKMDEKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTLGVATMCVGLGQGITTVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_SULNB
Sequence: MNKERYIGIMSGTSLDGVDVVLCEIDKKSCLLKASVEYPFPDDLKKEILSMINGKCTLAQVGSVDVRLGILFSDAVNALLEIEKIDPKSIKAIGSHGQTLWHEPVGKYPFSMQLGDPSAIAVRTGIKVVADFRQKDMALGGQGAPFAPAFHAFLFGGTDASVSILNIGGMANITVLGKTLLGYDTGPGNVLMDMWVAEHKDVTYDRNGEWARSGEVIYPLLEAMLEDPYFSQPHPKSTGREKFNEAWLQKHLNAQHSTLNAHDVQRTLLELTAVSISNEVLKFNQDILLLCGGGAKNAFLVERLGTLMPNIQIGIANDADNIEAMTFAWLAYKRLHNEHVDLKDVTGARQNAILGGVYV
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: URE2_ALIFM
Sequence: MIPGELRVNDDLGQIELNVGRTTQTLSVANYGDRPIQVGSHYHFYEVNEALHFEREPTKGFRLNIPAGMAIRFEPGQRRTIELVEFAGKREIYGFQAAIMGNVDGHITATISDDKEVK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_SULDN
Sequence: MSEFYIGVMSGTSLDGIDLALCEIEDDAFELLLCASYPFDAELKSDILNAINAQTTLKNIGEIDIRLGKMYADALEKFIEENSLKRVKIRAIGLHGQTLWHEPESQNPFSMQLGNANILTARLGICVVSDFRQKDIALGGQGAPFTPAFHEFLFSKLSGNVAVLNIGGMANITLLREMLSGYDTGCGNVLMDYWISKYNGSPYDKDGEWAKSGTPNRELLREFLKEPYFLKSPPKSTGRELFGEKWLKKQLSEFAKKNQNCSYLKARDIQATLLELSVQSIANEIKKSDTTLLIVCGGGINNRYLMERLQEELGDIKIASSDEYGVSSEFMEAMAFAWLAHERIHKKCVKISSVSGALRDSILGAIYE
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: CLPP_YERPP
Sequence: MSYSGERDQFAPNMALVPMVVEQTSRGERSYDIFSRLLKERIIFLTGQVEDHMANLITAQMLFLEAENPEKDIFLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQACSMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGFQGQATDIEIHAKEILKVKSRMNELMAYHTGKSLEEIERDTERDRFLSAEQSVEYGLVDSVFTRRD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YE077_YEAST
Sequence: MTLGNSYDAFNHDPWMDVVGFEDPNQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCYEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRCGCLNVAPVRNFIEEGYDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIRKKVESQPEEALKLLLALFESEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLDAAEKVSRTKEFVTDGNMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSNFQESNSSDRYRKYCSSDEDSNTCIHGSANASTNASTNAITTASTNVRTNATTNASTNATTNASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTASINVRTSATTTKSINSSTNATITESTNSNTNATTTESTNSKTSATTTASTNSNTSATTTESTNSKTSATTTASTNSNTSATTTESTNSNTSATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRREIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCQEEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQIALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADNTKVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVGE
What is the function of this protein?
Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.
What are the official names of this protein?
Y' element ATP-dependent helicase YEL077C.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
Protein: Y822_METMA
Sequence: MRSMSFEEAIKSLDSGIIVDIEVTPGSRSLSVPSGYNEWRKRIEVKLTRNAQKGKANEQLIESLAELFGICSSDIFISSGATSSKKSLLIKGVSYQQAVLVFGKHLKG
What are the official names of this protein?
UPF0235 protein MM_0822.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: CFXQ_GALSU
Sequence: MNVITETEYKEENINENTLVNIQEEYKKTKIQEVLNQLDKELIGLTPVKNRIKEIAALLLIDKLRIKLNLPQANPGLHMSFTGSPGTGKTTVATKMADILYLLGYIRKGHLLTVTRDDLVGQYIGHTAPKTKEVLKRAMGGVLFIDEAYYLYKPDNERDYGSEAIEILLQVMENQRNDLVVILAGYKDKMERFYQSNPGLSSRITNHVDFPDYTAEELLEIGIMMLEEQQYQLTEEGKKVLLEYIKRRMTQPHFANARSIRNAIDRARMRQANRIFNSSNRVLTKKDLVTIEAEDILKSSLFMDK
What is the function of this protein?
Necessary for the expression of RuBisCO.
What are the official names of this protein?
Protein CfxQ homolog.
What is the protein family that this protein belongs to?
Belongs to the CbxX/CfxQ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MOAC2_MYCTU
Sequence: MARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase 2, Molybdenum cofactor biosynthesis protein C 2.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: S22AC_MOUSE
Sequence: MAFPELLDRVGGLGRFQLFQTVALVTPILWVTTQNMLENFSAAVPHHRCWVPLLDNSTSQASIPGDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRKAEGDTLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLALDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRFCQVSFLVLPGLCILSNILVPHGMGVLRSALAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQDIQKQSVKKVTHDTPDGSILMSTRL
What is the function of this protein?
Electroneutral antiporter that translocates urate across the apical membrane of proximal tubular cells in exchange for monovalent organic or inorganic anions (PubMed:14747372).  Involved in renal reabsorption of urate and helps maintaining blood levels of uric acid (PubMed:14747372).  Mediates urate uptake by an exchange with organic anions such as (S)-lactate and nicotinate, and inorganic anion Cl(-) (PubMed:14747372).  Other inorganic anions such as Br(-), I(-) and NO3(-) may also act as counteranions that exchange for urate (By similarity).  Also mediates orotate tubular uptake coupled with nicotinate efflux and to a lesser extent with lactate efflux, therefore displaying a potential role in orotate renal reabsorption.  Orotate transport is Cl(-)-dependent (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 12, Renal-specific transporter, RST, Urate anion exchanger 1, URAT1, Urate:anion antiporter SLC22A12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Protein: CSEN_MOUSE
Sequence: MQRTKEAVKASDGNLLGDPGRIPLSKRESIKWQRPRFTRQALMRCCLIKWILSSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI
What is the function of this protein?
May play a role in the regulation of PSEN2 proteolytic processing and apoptosis.  Together with PSEN2 involved in modulation of amyloid-beta formation (By similarity).
What are the official names of this protein?
Calsenilin, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, DREAM, Kv channel-interacting protein 3, KChIP3.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Endoplasmic reticulum. Golgi apparatus. Nucleus. Note=The sumoylated form is present only in the nucleus. In the presence of PSEN2, associated with the endoplasmic reticulum and Golgi.
Protein: UVRC_STRA1
Sequence: MNELIKHKLELLPDSPGCYLHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTTSNTEALLLEINLIQENMPKYNIRLKDDKSYPYIKITNERYPRLMITRQVKKSDGTYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCFYYHLGQCNAHTVCQTNKAYWDSLREDVKQFLNGKDNKIVNGLTEKMKSAAMTMEFERAAEYRDLIEAISLLRTKQRVIHQDMKDRDVFGYFVDKGWMCVQVFFVRNGKLIQRDVNMFPYYNEPEEDFLTYIGQFYQDTKHFLPKEVFIPQDIDAKSVETIVGCKIVKPQRGEKKQLVNLAIKNARVSLQQKFDLLEKDIRKTHGAIENLGNLLNIPKPVRIEAFDNSNIQGTSPVAAMVVFVNGKPSKKDYRKFKIKTVIGPDDYASMREVIHRRYSRVLKDGLTPPDLIVIDGGQGQVNIARDVIENQLGLAIPIAGLQKNDKHQTHELLFGDPLEVVELPRNSEEFFLLHRIQDEVHRFAITFHRQLRSKNSFSSKLDGITGLGPKRKQLLMKHFKSLPNIQKADIEDIIMCGIPRTVAESLRDSLNDPPK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_PSEPW
Sequence: MNAESRIHALRAELDQHNYRYYVLDEPSVPDAEYDRLFNELKALEAEHPHLVTPDSPTQRVGGAALAAFSQVRHEVPMLSLGNAFEEADLREFGRRVVDGLDQPGAVDYSCEPKLDGLAVSLLYRDGQLVQGATRGDGTTGEDISANVRTVRNIPLKLQGKGWPAVLEVRGEVFMSKAGFDRLNAAQAEAGGKTFANPRNAAAGSLRQLDSKITASRPLEFCCYGVGQVSASIGESHIGILEQLKAWGLPISRELRHAAGIEECLAYYRDIGERRNSLPYEIDGVVFKVNSLASQRELGFRAREPRWAIAHKFPAMEELTEVLDVEFQVGRTGAVTPVARLKPVKVAGVTVSNATLHNMDEIARLGLRIGDTVIIRRAGDVIPQVMQVVLERRPEDARPVQVPSACPVCGSQVERTQLVKRSKGKETTSEGAVYRCVGRLACGAQLKQAIIHYVSRRAMDIDGLGEKSVEQLVDEGLIGSPADLYKLQFDQIVGLEGFAEVSSKKLLDAIEASKRPSLARFIYALGIPDVGEETAKVLARSLGSLARVQQALPQVLTYLPDIGLEVAYEIHNFFEDEHNCKVIEQLLGCGMQLQDEGELAAEFAASTTLAGMIAKLDIASVGPTGAEKLVAKLDSLDKIIAADGIDLRQALAAKQAEAVREFFKDEANQKLARDIEAQLLAFGMHWNSEKKVAEGLPLAGQTWVLTGTLERMSRDIAKEKLESLGAKVAGSVSGKTHCVVAGPGAGSKLAKASELGVKVLDEDAFVVFLDEQGIAI
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RK14_ARATH
Sequence: MIQPQTYLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAIPNTPLERSEVIRAVIVRTCKELKRNNGTIIRYDDNAAVVIDQEGNPKGTRVFGAIPRELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL35_KLEP3
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: YQGF_STAAW
Sequence: MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX7R_HUMAN
Sequence: MYYKFSGFTQKLAGAWASEAYSPQGLKPVVSTEAPPIIFATPTKLTSDSTVYDYAGKNKVPELQKFFQKADGVPVYLKRGLPDQMLYRTTMALTVGGTIYCLIALYMASQPKNK
What is the function of this protein?
Involved in the regulation of oxidative phosphorylation and energy metabolism (By similarity).  Necessary for the assembly of mitochondrial respiratory supercomplex (By similarity).
What are the official names of this protein?
Cytochrome c oxidase subunit 7A-related protein, mitochondrial, COX7a-related protein, Cytochrome c oxidase subunit VIIa-related protein, EB1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: RUTF_BRADU
Sequence: MRMRMQDVAPQDYRDAMACLGAAVNIVTTDGSAGRAGFTASAICSVTDDPPTLLVCINRGSSAYSSVTRNEVVCVNVLSARHEPLSRLFGGKVPADERFAAAAWSTLATGAPVLADCSAAFDCRIADTVNVGTHDVLFCRVVALQRFGCTDNLIYFGRAYHTVGVTDPAEAGPESALDAS
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: A4_DORPE
Sequence: MGPSVRPGFLVVVIGLQFVAASMEVNSRKFEPMVAFICNKPAMHRVPSGWVPDDDPAKSCVKQPEEILEYCKKLYPDHDITNVLQASYKVTIPNWCGFNVTHCHKHGNHTVRPFRCLVGPFQSEALLVPEHCIFDHYHDPRVCNEFDQCNETAMSKCSARGMTTQSFAMLWPCQEPGHFSGVEFVCCPKVSLIPESTEAPKSSPPTPAKTENGLDDYTAYLKGDSKYMSKYANEHERFKAAEKVMQQFQRERDTKMMKDWKAARDSVREKKKTDPKKAMELNKELTERYQKIYHAYEQESIAEKKQLVNTHQQHIQSWLNNRKQVLMEKLQDALLAKPPKKSKIEKAATAYIKVEEKDKMHTYNHFQHLRDTDPEDAANIQDRVLEHLNLIDDRIRRVLDWLKRDPEIEKQVRPNIDKFMAKYKDINANSMKLLLRQEPTPKEAPVETQKAEDYSEEDEAAVTGTANKVKPTEARPEQQEDIKTPGFDSETFEDERPAIAEQTIHDLPNHRKKGYIAHVQQQPMIADEVSLDNLYANSHANSVLGIAIGGVVVFIIIVVAVVMLKRRTQRQRVTHGFVEVDPAASPEERHVANMQMSGYENPTYKYFEMQNQ
What is the function of this protein?
Acts as a kinesin I membrane receptor, thereby playing a role in axonal anterograde transport of cargo towards synapes in axons.
What are the official names of this protein?
Amyloid-beta precursor-like protein.
What is the protein family that this protein belongs to?
Belongs to the APP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon.