PharMolix/UniProtQA huggingface dataset:
Protein: PIF7_TRYB2
Sequence: MWDGPLRSRQNLRTVAKLRSSGCPLTQSAIHPTTTSPSEGETASEILQGQASAGYIEEQQLPATSSQLEMSGDSNAASDNNVVIMTKRQRDDLSQASQAEVLSRLRTEDAQGPAENNGAQSDLALHSCDMEERVDSSKLNLNHVTVNKHSPPASKSAGISQQNDDGGCGASENVDNTTTAASKQRGKLLLDSSSSNCTPKQQAQQAVTQVPEWELSHEQERIFDIVVNHRRSVFLTGGAGTGKSHLLRAIIAALPLSTTFVTATTGLAALNLGGTTLHSFSGCGFVDQHTSTHQMVYRNVLGRKKARANWRKCRVLVVDEVSMLDAWFFDMLEYVARHIRGCRKPFGGIQLVLSGDFLQLPPVNKHSPKQETRLCFEAKSWPRVNPLVCTLSHQFRQKDKEFFSLLNEVRVGALTAPSLGLLSSLSVITTVSFVDEEKLKLKREVGAEAVDIITDSKGRTRRQRQDGFTILRARRSEVDAINTEKFGELDTEIYSYKGAHRGEGHFPSDLPSTVSVRAGCRVMLLANLDLSAGLANGSIGTVESFVSSKLHQTANPSTKDDLQHLADHMMLPVVRFDHKGKQGPGDGGGAAAGRLVVIEPHRWTMRQGDSDVSCSIQIPLQLAYAITIHKSQGMSLSHVNVDFAGIFEEGQAYVALSRCTDVANLVIENFDAQRVNPNIKALAYYRALEFVGTEHREAEKKLIDNGNKMNPWGPYDVEDFEASDDDNGGAVKKEVVENLTYDAENISCMVEQFRQRYMPQYIMFSTLRRRVLSNTEDAARVKGALLVMDTTSLLALTNMTGPTSLYQTIFTERGNMMRVPRVVKEELLFLASTDVKEVSSVTTPTLHSFCSTCSSTPCSTGFSYDFVEVVSCALSIMENAKCDFLLDEQREGEANSLPPVIQEWRSLSPLLMLNSSPDTGEKDAPSVIGFGERSREQHHSTLMFASFLVSRYSGNGAVYVCTETVELAARALAIGLRVCSIAYLCNRARRVN
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of mitochondrial (kinetoplast) genome stability.
What are the official names of this protein?
ATP-dependent DNA helicase PIF7, DNA repair and recombination helicase PIF7.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PIF1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix, kinetoplast. Note=Localizes predominantly to the kDNA disk.
Protein: END1_BUCAI
Sequence: MKKFCFLKIEKIKNDKKNVYCYNKYVFFFSSNKRSYFKKKTIENFYQAKIISIKIHKNAPGSFYCGCQIIWKQKKGIPNLYSCGYKIRKNKNRATRIEWEHVVPAWQFGHQKTCWKKGGRKKCMEDKKYKHIESDLHNLQPAIGEINGDRSNFMYGQLNNSVAQYGRCNMKIDFKRKIVEPPERARGAIARTYFYMNKKYNIILSEKERKMFTIWDKIFPVTKWECEREKLIFNIQGNHNDYVYKHCYKK
What is the function of this protein?
Has double-strand break activity.
What are the official names of this protein?
Endonuclease-1, Endonuclease I, Endo I.
What is the protein family that this protein belongs to?
Belongs to the EndA/NucM nuclease family.
Protein: DNAK_TROW8
Sequence: MSRAVGIDLGTTNSVVAVLEGGEPNVIANAEGLRTTPSVVAFSRDGEVLVGDTAKRQAVTNVDNTISSVKRHIGTDWTKQIGDKKYTPQEISARILSKLKRDAEQYLGEKVTDAVITVPAYFNDAERQATKEAGEIAGLNVLRIINEPTAAALAYGLDKGKEDELILVFDLGGGTFDVSLLEVGKDDDFSTIQVRATSGDNRLGGDDWDQRIIDWLVDDFRKTTGVDLSSDKIAMQRLREASEQAKKELSSATSANIQLPYISLTESGPVNMDTTITRAQFEKMTEDLLERTKNPFRDVLKEAGVSVDKISHVVLVGGSTRMPAVSDLVKRETGKEPNKGVNPDEVVAVGAALQAGVLRGERKDVLLIDVTPLSLGIETKGGIMTKLIERNTAIPTKRSEVFTTAEDNQPSVSIQVFQGERELTQDNKNLGTFELTGIAPAPRGLPQIEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGSGLSQDEIDRMIKEAEEHAAEDKNRRARVDQKNQAEQMVYTAEKLIGDNAKVNEEAKKELQADIDSLKSAIQADDHDLIKAGTDKLLASQQKFAQSVYETTKDDPKEQVVDAEVVDEDSGSSK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SDC25_YEAS8
Sequence: MSRTASYAGMTTPVKDKEGHGIPCLQPIDVVECTYQYFTKSQNKLSLRVGDLIYVLTKGSNGWWDGVLIRHSANNNNNSLILDRGWFPPSFTRSILNELHGVPEIGNELEIFQAGLNLKLELSSNPVILSLEDFLDCCRDIEFKEQLAWSPIPVHERKGCCELLYYNQDLDVYCRTLPYLPQNQVETVNDYSSFPAISKIAGKKMPITSSPDLFYLNDCDVVYWYDLTRLVCHYVNLTERDLLANEREKFLTSLDLLTAQITYVYMLFRNLRLVEDSFKKTLKKLIYTLSRFSINANIWFHSTPFEEREAIASQKDPERRSPLLQSILGTFQKFHFLLRLLHFLSNPNELTILPQLTPRFFKDSFNTISWNNPFLRKHLNQHMSHDLPRQMIKAVAGASGIVAENNDEIPASKQGTSCSSETSHHSPSAPFQRRRRGTIFSNVPGSSDESDTIWSKRKKPYPLNEETLSLVRARKEQLDAKLKQMIKSANEYLSNTANFSKMLNSEMNFKTYEEVSGTIPIIDILENLDLTIYLNLRELGDENRVFDEDVAIDDEDKEFLKHSLSSLSYILSDYFNMKQYFHDVVVKFIIVAQHLTLEDPFVFSPMQNDLPTGYYEPMKPSSLNLDNAKDKKNGSQNTDIQEEEDEYEPDPDSLILFHNLINQDSDFNDLKFFNLAHVFKKSCDDYFDVLKLSIEFVNRLILERENLLNYAARMMKNNITELLLRGEEGYGSYDGGETAEKSDTNAVYADSDTKDNDEWRDSQVKLPRYLQREYDSELIWGSNNRIKGGSKHALISYLTDNEKKDLFFNITFLITFRSIFTTTEFLSYLISQYNLDPPEDLCFEEYNEWVTKKLIPVKCRVVEIMTTFFKQYWFPGYDEPDLATLNLDYFAQVAIKENITGSVELLKEVNQKFKHGNMQEATAPMKTLDQQICQEHYWGTLYSTTESILAVDPVLFATQLTILEHEIYCEITIFDCLQKIWKNKYTKSYGASPGLNEFISFANKLTNFISYSIVKEADKSKRAKLLSHFIFIAEYCRKFNNFSSMTAIISALYSSPIYRLEKTWQAVIPQTRDLLQSLDKLMDPKKNFIDYRSELKSLHSAPCVPFFGVYLSDLTFTDSGNPDYLVLEHGLKGVHDEKKYINFNKRSRLVDILQEIIYFKKTHYDFTKDRTVIECISNSLENIPHIEKQYQLSLIIEPKPRKKVVPNSNSNNKSQEKSRDDQTDEGKTSTKKDRFSKFQLHKTKKKAPKVSK
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP.
What are the official names of this protein?
Guanine nucleotide exchange factor SDC25.
Protein: HIS2_MYCVP
Sequence: MTQSPNVKTFDALFAELSERARTRPAGSGTVAALDGGVHGIGKKILEEAGEVWLAAEHESDEALAEEISQLLYWTQVLMLSRGLSLDDVYGKL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDUB1_CHLTJ
Sequence: MLSPTNSISKTAPVPPQDSSKPVLISEEPQNQLLQKVARTALAVLLVVVTLGLILLFYSFSDLQSFPWCCQTRPSTKEQPTISIPVPLPSPPLAVPRPSTPPPPVISRPSTPPAPTPAISPPSTPSAPKPSTPPPLPPKAPKPVKTQEDLLPFVPEQVFVEMYEDMARRRIIEALVPAWDSDIIFKCLCYFHTLYPGLIPLETFPPATIFNFKQKIISILEDKKAVLRGEPIKGSLPICCSEENYRRHLQGTTLLPVFMWYHPTPKTLSDTMQTMKQLAIKGSVGASHWLLVIVDIQARRLVYFDSLYNYVMSPEDMKKDLQSFAQQLDQVYPAYDSQIFSVKIAAKEVIQKGSGSSCGAWCCQFLHWYLRDPFTDALNDLPVDSVERHENLASFVQACEAAVQDLPELFWPEAKALF
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease possesses deubiquitinating and deneddylating activities (By similarity).
What are the official names of this protein?
Deubiquitinase and deneddylase Dub1, ChlaDub1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Secreted. Host cell. Membrane; Single-pass membrane protein. Note=Secreted, and delivered into the host cell.
Protein: GSA1_STAES
Sequence: MSFEKSIKAMEQAEKLMPGGVNSPVRAFKSVDTPAIFMDHGEGSKIYDIDGNEYIDYVLSWGPLILGHKNQQVISKLHEAVDKGTSFGASTLQENKLAELVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIIKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDSLKLAFEKYGDDIAGVIVEPVAGNMGVVPPVNGFLQGLRDITNEYGALLIFDEVMTGFRVGYNCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDYIAPVGTIYQAGTLSGNPLAMTSGYETLSQLTPESYEYFNSLGDILEKGLKEVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEEANKSDLKLFSNMYREMAKEGVFLPPSQFEGTFLSTAHTKDDIEKTIQAFDNALSRIV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_METVS
Sequence: MLVIKADYKKYPLPVLESMRINEDEFYGKYDACIIVQTCNRIEAYFDEEINDIEKIIPDFKGFDVIKGKKATLHFLNVACGMDSMILGENQILGQIKSSYHKSKELKKTSKYLENLFLKAIHVGQRVRAETKINEGGVSIGSAAVELAEMKLGLKNRNVLLIGAGEIGTLVAKALIEKHIKAVIVANRTYERAETLAKELKGMAVHFDKLKEAINFSDVIICATSSPHYILEKSDLLDVGNKIIIDIANPRDVDDSVRELENISLYTIDDLRNISDKNLQKRLKEVPIVENIIEEEYGILLKQIEKTNVEEVIKDFNTYIEDVRKKELEKAVRLCKNKSPDEIMENFSKAFVKRITHDFVSYSLSVSKEDLLNSIWWKK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: METN_BRUAB
Sequence: MQHAAVCSGTSRHRRTTVTIEKPPATSAPIVEMKDVRRMFGETAAINGVSLSVARGEILGIIGRSGAGKSTLIRCVNGLEKPDTGSIHIEGREITSLDEDALRPVRRRIGMVFQHFNLLSAKTAAQNIALPLKIAGMPKAERIKRVAELLELVGLSDKASHYPAQLSGGQKQRVGIARALAAEPAVLLSDEATSALDPETTQSILALLKDINAKLGLTILLITHEMDVIRRIADRVIVLDHGLIAEEGPVWKVFANPQSPVTQSMLQVLTPELPAIWRNRLEKKGDQAILRVKLSGMAAKGAFFNDVAAATSLAPQLIHGGMDTIQGEPVGTLFIGLPAEDKTKLKAAIGYLNTHADATEVLGYVSGNA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NADA_HAHCH
Sequence: MSAISDRIFVQEHLAREHEASELSPEEAERLKAEIKELLVQEDAVLVAHYYTDPLLQALAEETGGCVADSLEMARFGNQHPASTLMVCGVRFMGETAKILNPEKTVLMPTLEATCSLDIGCPVEEFSAFCDEHSDRTVVVYANTSAAVKARADWVVTSSIALDIVEYLHERGEKIIWAPDKHLGGYVKNKTGADVLLWDGSCIVHEEFKSKGLSDLKQLYPDAAVLVHPESPEAVVEMADVVGSTSQLINAVKSMSNEQFIVATDAGIFYKMQQMAPEKTLIEAPTAGNGATCRSCAHCPWMAMNGLENLRDVLISKRQEIIVEADLREKALIPLQRMLNFSKERQMAVKGNA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRS16_ARATH
Sequence: MAAITISSSLHASASPRVVRPHVSRNTPVITLYSRFTPSFSFPSLSFTLRDTAPSRRRSFFIASAVKSLTETELLPITEADSIPSASGVYAVYDKSDELQFVGISRNIAASVSAHLKSVPELCGSVKVGIVEEPDKAVLTQAWKLWIEEHIKVTGKVPPGNKSGNNTFVKQTPRKKSDIRLTPGRHVELTVPLEELIDRLVKESKVVAFIKGSRSAPQCGFSQRVVGILESQGVDYETVDVLDDEYNHGLRETLKNYSNWPTFPQIFVKGELVGGCDILTSMYENGELANILN
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides (Probable).  Participates probably to the maturation of iron-sulfur proteins and to the regulation of the redox state of the BOLA proteins (Probable).  The GRXS16-BOLA1 heterodimer binds a labile, oxygen sensitive iron-sulfur cluster (PubMed:24714563).  Able to cleave linearized DNA in vitro (PubMed:23690600).
What are the official names of this protein?
Bifunctional monothiol glutaredoxin-S16, chloroplastic, AtGrxS16, Atypical GIY-YIG endonuclease, CAX-interacting protein 2, CAXIP1-like protein.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CGFS subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EXOC2_MOUSE
Sequence: MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKCKLPQKNLEVLFHGMSADFTSENFSAAWYLIENHSTTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGHPGPHSPMLDLDNDVRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQSERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPLSLREGDGRQYGGWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIRCIMVTLQHTAEEIKRLAEKEDWVVDNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKTQEEVCQLCINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDTVAIYLTSESRSSFKQALEALPQLASGADKKSLEELLNKFKSSMHLQLTCFQAASPAVMKT
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 2, Exocyst complex component Sec5.
What is the protein family that this protein belongs to?
Belongs to the SEC5 family.
What are the subcellular locations of this protein?
Midbody, Midbody ring. Note=Recruitment to the midbody does not require RALA, nor RALB. Colocalizes with CNTRL/centriolin at the midbody ring.
Protein: CSF12_TAKRU
Sequence: MKSYCLLLSITLSCCCSAEDLPDPPSIHLNSKYLPNQAEAILTAGTPFTLRCTGASSVHWSSSAFCLLYHGRLVDPIDVQRADPRHTGTYCCGYTNQSLEHLSTWIHLYVKDPADPSTVFVTPRNSPRVKEGQDFLYRCLLTDPSVTNLTFQPEDNIQGSGQHLPVGMNVTVDPQRGALIQDVQRSFSGQYVCSGWKDGRHFISRSFHLLVAPRLPPPSVAIHQNKAVRLEGEKFEVTCVSSSTTHLFNVTWTHLTKKNFDVAVTREYRNSHMYISSTLMIAAVSQEDRGTYTCAAASEDGVTTATTHLIVLDSRFMTTYLKTWHANTKAKNKEISKEIDGNLTANSTSIDIEANRSSKLHMKMELIANVSTDGVHVNNISSSTTVEAYEGLDVILTFVTESYPPLSNQSWTKPTKVNNNNNVTMYQENYSINDTRSEASLLLRRVRQEDHGSYTFHFSNSFFSGSQNIDLRIYRSPSAIISVEKNTLTCSSSGYPVPTIAWYSCPGILKTCGNLTTTESSEADPTSEHDEENVRKLLNLPLSTGGDVTAECIASNQVGAFRKVFHLREHNSAFMSALIGAGSTAAILFLLLLVVFYKWRQKPKYEIRWKIIESTEGNHYTFVDPTLLPYNYKWEFPRDKLRLGAVLGSGAFGKVVEATAYGLGTDDVTRVAVKMLKPRALSEEREALMSELKILSHLGYHDNIVNLLGACTQGGPMLMITEYCSYGDLLNFLRARAQDFMASILSADEMEGDPFYKNMATLYGRLRSDSGISCCSDYQEMQPILGSAEKQQGVQMGGLSFGDLLSFSHQVAQGLDFLSTRNCIHRDVAARNVLLTDHRVAKICDFGLARDIQNDDSYIVQGNARLPVKWMAPESIFQCVYTVQSDVWSYGVLLWEIFSLGKSPYPNVAVDTHFYKMIKDGRHMTQPDFAPVEMYQLMTHCWSLEPTDRPTFKMICQLIDRLLQSNDDTNHQSYSNINETKKDDFKGGKSQRRGEEEEQRRQRGNLWIPLSVTNIYQLS
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.  Plays an important role in innate immunity and in inflammatory processes.  Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development.  Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.  Activates several signaling pathways in response to ligand binding (By similarity).
What are the official names of this protein?
Macrophage colony-stimulating factor 1 receptor 2, CSF-1-R 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=The autophosphorylated receptor is ubiquitinated and internalized, leading to its degradation.
Protein: Y521_METCA
Sequence: MADAPFWHAKALAELSLAEWESLCDGCGKCCLHKLEDEDTGEILYTRVACRLLDIAACRCTAYQDRFRLVPDCMDLRQVPDQFHWLPASCAYRLLSEGRPLPAWHPLVSGAADSVHRAGKSVCRLAVSETVVDCIEDHVIEGLGDAV
What are the official names of this protein?
UPF0260 protein MCA0521.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: RIMM_STRZJ
Sequence: MNYFNIGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEKDQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYHEIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRVDVEILEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QORX_HUMAN
Sequence: MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of quinones (PubMed:19349281).  Exhibits a low enzymatic activity with beta-naphthoquinones, with a strong preference for the ortho-quinone isomer (1,2-beta-naphthoquinone) over the para isomer (1,4-beta-naphthoquinone).  Also displays a low reductase activity for non-quinone compounds such as diamine and 2,6-dichloroindophenol (in vitro) (PubMed:19349281).  Involved in the generation of reactive oxygen species (ROS) (PubMed:19349281).
What are the official names of this protein?
Quinone oxidoreductase PIG3, NADPH:quinone reductase PIG3, Tumor protein p53-inducible protein 3, Protein PIG3, p53-induced gene 3 protein.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: COPZ_STAAB
Sequence: MSQEILNVEGMSCGHCKSAVESALNNIDGVTSAEVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
What is the function of this protein?
Chaperone that serves for the intracellular sequestration and transport of Cu(+).  Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA) (By similarity).
What are the official names of this protein?
Copper chaperone CopZ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4B_CLOBL
Sequence: MAKIRDPRFKLSRRLGVNIYGHPKAMKRATRENSREGKKLSNYGKQLLEKQKIRSYYGVLEKQFLRYVKKAMKSKERTGDVLLRSLECRLDNIAYRIGFANSIRQARQMVNHGHILVNGSKVNIPSYEVKAGDVITLREKYRKNDEFADNFLSLKKFSLPYIEKDYDKFSGVLIKEPERDEIPIDANETLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4 B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RLME_SHIBS
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1038_HALSA
Sequence: MELTWFGHSTWRVTVGTTDLLVDPFFDNPHTDTAPSEVAVDHVLLTHGHADHIAHVGAFADTHTVGTPEVTGYVADETGVEDTTGMNLGGTVELGDAFVTMVRADHTNGLETGYEYSGGTPVGYVISDAAPTQTGDGDATTFYHAGDTSLQSEMKDVIGPYLDPDAAAVPVGDHFTMGPMQAAVAVDWLDVDVAFPMHYDTFPPIEVDTADFEREVNATGSQADVHVLDGDETVDLSDAL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase VNG_1038C.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: KAD4_ARATH
Sequence: MATGGAAADLEDVQTVDLMSELLRRLKCSQKPDKRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDDLVVGIIDEAMNKPKCQKGFILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEERITGRWIHPSSGRSYHTKFAPPKTPGVDDITGEPLIQRKDDNADVLKSRLAAFHSQTQPVIDYYAKKAVLTNIQAEKAPQEVTSEVKKALS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase 4, AK 4, ATP-AMP transphosphorylase 4, ATP:AMP phosphotransferase, Adenylate monophosphate kinase 4, AMK4.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_MYCGI
Sequence: MAQQAPDREKALELALAQIDKNFGKGSVMRLGEDVRPPIAVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGIAAFIDAEHALDPDYAKKLGVDTDALLVSQPDTGEQALEIADMLIRSGALDILVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLREKIGVMFGSPETTTGGKALKFYSSVRLDVRRIETLKDGTDAVGNRTRVKVVKNKVSPPFKQAEFDILYGKGISREGSLIDMGVEQGFIRKSGSWFTYDGEQLGQGKENARNFLLQNPDVGNEIEKKIKEKLGIGAQLTDDVADDALPAPVDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_BURCH
Sequence: MTKLTARQQQVFDLIRRAIERSGFPPTRAEIAAELGFSSPNAAEEHLRALARKGVIELAAGASRGIRLLGIDDAPHQFTLPHAGLMQLSLPLVGRVAAGSPILAQEHISQHYACDPALFTSKPDYLLKVRGLSMRDAGILDGDLLAVQKRTEAKDGQIIVARLGDDVTVKRLMRRPGGLELIAENPDYENIFVKAGSADFALEGIAVGLIRSGEL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: PRXC_SYNY3
Sequence: MPYVTVGQENSATIDIYYEDLGAGQPIVLIHGFPLNGDSWEKQVLVLLNAGYRVITYDRRGFGASSQPSSGYDYDTFAADLHTLMTKLDLQNTVLVGFSMGTGEVTRYLGKYGSERVQKAVLMAPVPPFLLKTNDNPEGVDQSVFDGIMKAIVDDRPAYFSAFFKEFFNVDVLLGERISNEAIQASWNVAAGASAKGTLDCVPSWLTDFRDDLPRIDVPTLIIHGDADRILPLESTAARLPKRIKNSQLEIIPGGPHAINWTHADQVNPLLLNFLQ
What are the official names of this protein?
Putative non-heme chloroperoxidase, Chloride peroxidase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Bacterial non-heme haloperoxidase / perhydrolase family.
Protein: RS14_BORPA
Sequence: MAKLSLINRDIKRAKLADKYAAKRAELKAIIDDQSKTDEERYQARLKLQQLPRNANPTRQRNRCVVTGRPRGVFRKFGLTRHKLREMAMKGEVPGMTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: Y985_STAAE
Sequence: MNLIPRTSIVVYLKHMKHERQIRKYGHIVHSNRDRKFVIMYVNEQDVDQIVHKLMQLKYVRHIDGSPYKYLKKTYEKEKHEIYN
What are the official names of this protein?
UPF0298 protein NWMN_0985.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P20D2_MOUSE
Sequence: MGPVVERPAEPGTSSAAELELLKRRAAERIDEAAERLGALSRAIWSAPELAYEEHRAHGELTRFFECEPPAASWAVQPHFGLPTAFRAEWAPPESAAGPRALQVAFLCEYDALPALGHACGHNLIAEVGVAAALGLRAALESIAAPPPVKVIVLGTPAEEDGGGKIDLIEAGAFENLDVVFMAHPSQENAAYLPDVAEHDVTVKYYGKASHAAAYPWEGVNALDAAVLAYTNLSVLRQQMKPTWRVHGIIKNGGVKPNIIPSYSELVYYFRAPSMKELQVLTKKAEDCFRAAALATGCTVDIESEAHDYYNVIPNKTLCSAYTENGKKLGMEFISEDAVLNGPSGSTDFGNVSFVVPGIHPYFYIGTDALNHTEQYTEAAGSQAAQLYTLRTAKALAMTALDVIFKPALLEGVRKEFKCKLQEEQLLNTAA
What is the function of this protein?
Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus.  Postulated to function in a metabolite repair mechanism by eliminating alternate dipeptide by-products formed during carnosine synthesis.
What are the official names of this protein?
Xaa-Arg dipeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: Y1201_AQUAE
Sequence: MSLTSSIRDKLYCMAEKKISEERRESTTQTAEELKVPSMEKELEELRREFFKFMEFCIPPKEVRDEVMKNLYNIPLSILKAFRTILDYEIKVLEERVKETERKPKSRRIAVE
What are the official names of this protein?
Uncharacterized protein aq_1201.