PharMolix/UniProtQA huggingface dataset:
Protein: HEMA_I76A4
Sequence: MEAKLFVLFCTFTVLKADTICVGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCSLNGIAPLQLGKCNVAGWLLGNPECDLLLTANSWSYIIETSNSENGTCYPGEFIDYEELREQLSSISSFEKFEIFPKASSWPNHETTKGVTAACSYSGASSFYRNLLWITKKGTSYPKLSKSYTNNKGKEVLVLWGVHHPPSVSEQQSLYQNADAYVSVGSSKYNRRFAPEIAARPEVRGQAGRMNYYWTLLDQGDTITFEATGNLIAPWYAFALNKGSDSGIITSDAPVHNCDTRCQTPHGALNSSLPFQNVHPITIGECPKYVKSTKLRMATGLRNVPSIQSRGLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITSKVNSVIEKMNTQFTAVGKEFNNLERRIENLNKKVDDGFLDVWTYNAELLVLLENERTLDFHDSNVRNLYEKVKSQLRNNAKEIGNGCFEFYHKCDDECMESVKNGTYDYPKYSEESKLNREEIDGVKLESMGVYQILAIYSTVASSLVLLVSWGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RL3_BURTA
Sequence: MSLGLVGRKVGMTRIFTAEGDSIPVTVLDVSDNRVTQIKTVETDGYTAVQVAFGSRRASRVTKPLAGHLAKAGVQTGEILKEFRIEADKAAELSNGAVIGPDLFEVGQKVDVQGVSIGKGYAGTIKRYNFGSGRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHMGDETVTVQNLEIARIDADRKLLLVKGAVPGAKGGKVFVTPAVKTRAVKGAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NADB_MYCBO
Sequence: MAGPAWRDAADVVVIGTGVAGLAAALAADRAGRSVVVLSKAAQTHVTATHYAQGGIAVVLPDNDDSVDAHVADTLAAGAGLCDPDAVYSIVADGYRAVTDLVGAGARLDESVPGRWALTREGGHSRRRIVHAGGDATGAEVQRALQDAAGMLDIRTGHVALRVLHDGTAVTGLLVVRPDGCGIISAPSVILATGGLGHLYSATTNPAGSTGDGIALGLWAGVAVSDLEFIQFHPTMLFAGRAGGRRPLITEAIRGEGAILVDRQGNSITAGVHPMGDLAPRDVVAAAIDARLKATGDPCVYLDARGIEGFASRFPTVTASCRAAGIDPVRQPIPVVPGAHYSCGGIVTDVYGQTELLGLYAAGEVARTGLHGANRLASNSLLEGLVVGGRAGKAAAAHAAAAGRSRATSSATWPEPISYTALDRGDLQRAMSRDASMYRAAAGLHRLCDSLSGAQVRDVACRRDFEDVALTLVAQSVTAAALARTESRGCHHRAEYPCTVPEQARSIVVRGADDANAVCVQALVAVC
What is the function of this protein?
Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
What are the official names of this protein?
L-aspartate oxidase, LASPO, Quinolinate synthase B.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRPB_RALSO
Sequence: MLGNIYFALASGLAARERLPEYANAVFAADFDRAYQLVDHHSSQRGKSDDYAGVLAMADASLLLECDEEAEEGFRLAQRLIRHSDDQLRVVSCRNTGWQALLRDRYAAAASCFSRMAEDDGATWTQQVEGLIGLALVHHQLGQQDASDDALRAAREAADGRSDRGWLATIDLIIYEFAVQAGIRCSNRLLEHAFWQSAEMGATLLANHGGRNGWTPTVSQGVPMPALIQRRAEYLSLLRRMADGDRAAIDPLMATLNHSRKLGSRLLMQTKVEVVLAALSGEQYDVAGRVFDQICNRETTYGARRWNFDFLYCRAKMAAQRGDAAGALKFYTTYMQDALRCLRTETVNVRRASAAVPVASRASDDVSARLSAKYRRAYRYIIENIERSDLTTREVAAHINVTERALQLAFKSAVGMSPSSVIRRMRLEGIRSDLLDSERNPSNIIDTASRWGIRSRSALVKGYRKQFNEAPSETIWR
What is the function of this protein?
Positive regulation of hypersensitive response genes involved in plant pathogenicity and partly of its own synthesis in minimal medium.
What are the official names of this protein?
Regulatory protein HrpB.
Protein: SELU_SALG2
Sequence: MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMIDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQEVANWLKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: Y2272_MYCTU
Sequence: MADDSNDTATDVEPDYRFTLANERTFLAWQRTALGLLAAAVALVQLVPELTIPGARQVLGVVLAILAILTSGMGLLRWQQADRAMRRHLPLPRHPTPGYLAVGLCVVGVVALALVVAKAITG
What are the official names of this protein?
Uncharacterized protein Rv2272.
What is the protein family that this protein belongs to?
To E.coli YidH.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATA_MARSD
Sequence: MSALIEKSLTEIHAMLMTKEVTATEAVKACLEQIAKSEPETKALLHICNDEALKQAEEMDAAGPDASKPLWGVPVVIKDALATNGIPTTAGSKILEGFTPFYDSTAVAKLKEAGAIIVGKANMDEFAMGSTTENSAYQTTTNPWDASRVPGGSSGGSGATVAAGQCYAALGTDTGGSIRLPASFCGCVGVKPTYGRVSRYGMIAYGSSLDQIGPMTRTVEDAARVLNVIGGHDQRDSTSAEQPMEDFVAALEERKDLSGLTIGLPEEYWGEGLSKEVSEACRAAIAKAEELGAKTVPVKLSMTEYAIATYYIIAMAEASSNLSRFDGVRYGHRTEDPKELAELYTKSRTEAFGDEVQRRIIIGTYVLSAGYYDAYYRKAAQIRRLLREDFNKAFESCDIIASPACPTTAFPVGELTSDPLQMYLQDIFTISLNLVGMPGMSLPVAFGKETNMPVGLQFMAPAFDEKTMLQAAHVLEKNLPELPKVKL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: GLGS_ECOLU
Sequence: MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQTRELELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.
Protein: ACPM_GORGO
Sequence: MASRVLSAYVSRLPAAFAPLPRVRMLAVARPLSTALCSAGTQTRLGTLQPALVLAQVPGRVTQLCRQYSDMPPLTLEGIQDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity).  Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain.  Accessory protein, of the core iron-sulfur cluster (ISC) assembly complex, that regulates, in association with LYRM4, the stability and the cysteine desulfurase activity of NFS1 and participates in the [2Fe-2S] clusters assembly on the scaffolding protein ISCU (By similarity).  The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis.  This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner.  Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly.  Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5 (By similarity).
What are the official names of this protein?
Acyl carrier protein, mitochondrial, ACP, NADH-ubiquinone oxidoreductase 9.6 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: XERC_RICTY
Sequence: MLDISIQELIKQWQKYLILQRNYSNNTVIAYNNDLKHFLEFMNYYNSELVTINHIKTVDIRLIRSWLAKRKYENFTASSIARGLSTVKNFYKFLEKTILLNSHIIFSIKSPKKAKLLPKALSVDDVLISLEHIEGYGNVKWVELRNKALLVLIYAAGLRISEALSITKLHLQNLEFIKIIGKGSKERIIPWLPFARNLITKYLGILPYKLDENEPIFRGKHGKKLQPSVFNRELIKLKRVYGLPEYLTAHSFRHSFASHLLEYGADLRSIQELLGHKSLSTTQKYTQTSIKHLEAVYNTAYPIKK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_GEOSW
Sequence: MRKIGIFGGTFDPPHYGHLLMANEVLHALQLSEIWFMPNRIPPHKQHEQVTKSEDRLRMLELAIADHPRFHIETIELEREGPSYTYDTIRQLLSMHPDHEFYFIIGADMVEYLPHWYKIAELIQLVTFVGVKRPGFSTETSYPIMEVEVPQFAVSSSMIRDRVRKGQTIRYLVPECVRLYIEERKLYGARKSVNSR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: GEAS_LAVPL
Sequence: MAQQEAEIIRPLANFSPSLWGDQFIKNDSDAKVEDKISKTIEVLKEEVKSMLTATGTKMVDTMNLIDTLERLGVSYHFEHEIEEILQQFFNLNTDYNDEAYDLYTVATHFRLFRQHGHRITCADIFGRWRDENGKFHEGLKDDAKGLLSLYEASYLRTRGETILDEALDFTTASLKSIAPNLESPLRRQVEHALVQQLHWGNPRIEARNFISLYEEYEDKDESLLRFAKLDYNLLQMMHKEELHEVSRWWKELDLVAKLPYARDRVVECFFWAMGVYHEPQYSRARVMLTKTIAMTSIIDDTYDAYGTIEELDIFTEAIERWNVEEMKRLPEYIKPFYKALLELYEQFEEELAKEGRSYATHYAIESLKELVRSYHVEAKWFIQGYLPPFEEYLKNALITCTYCYHTTTSLLGVESAVREDFEWLSKKPKMLVAGLLICRVIDDIATYEVEKDRGQIATGIESYMRDNGATKEEAITKFFEIANDAWKDINEECMRPSPHSRDVLMRILNLERIIDVTYKGNEDGYTQPEKVLKPHIIALFVDPIQI
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds widely used in aromatherapy and folk medicine, and present in culinary herbs (PubMed:24943828).  Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into germacrene A and beta-elemene (PubMed:24943828).  Not able to use (2E)-geranyl diphosphate (GPP) as substrate (PubMed:24943828).
What are the official names of this protein?
Germacrene A synthase, LpGEAS, Beta-elemene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VIL6_HHV8P
Sequence: MRWFKLWSILLVGSLLVSGTRGKLPDAPEFEKDLLIQRLNWMLWVIDECFRDLCYRTGICKGILEPAAIFHLKLPAINDTDHCGLIGFNETSCLKKLADGFFEFEVLFKFLTTEFGKSVINVDVMELLTKTLGWDIQEELNKLTKTHYSPPKFDRGLLGRLQGLKYWVRHFASFYVLSAMEKFAGQAVRVLNSIPDVTPDVHDK
What is the function of this protein?
Initiates signal transduction through binding to interleukin-6 receptor subunit beta IL6ST, independently of the cognate IL6 receptor IL6R.  In infected primary effusion lymphoma cells, promotes proliferation of cells, protects them from apoptosis, and promotes immune evasion of interferon activity.  Drives also blood to lymphatic endothelial cell differentiation.
What are the official names of this protein?
Viral interleukin-6 homolog, vIL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
Protein: HEM1_CAMJE
Sequence: MYYCISFTHKNTDIALREKLSFSNEAKKGEFLKIISTHENIEECLVISTCNRVEIVAFVKMACAEFIVKSLALLCDVDKDILLEKADIFEDSGAIHHLFSVASSLDSLVVGETQIAGQLKDAFAFAVKNNFCGVHLSRAVHSAFKCAAKVRNETQISKNSISVASVAVAKAKELADLTQKKAVVIGAGEMGELAAKHLIAAGAKVIILNRDLQKAKDLCERLGVLSEYDSLENLKKYLNQYEFFFSATNAPNAIITNSLIEELSYKRYFFDIAVPRDIDINENENISVFAVDDLEIVVQKNLALREQEARMAYGIIGRETSEFFRYLNDLALMPIIKAIRLQAKEYADKQLEIALKKGYLKKSDKEEARKLIHQVFKAFLHTPTVNLKHLQGKMQSDTVINAMRYVFDLQNNLEGLNQYKCEFDMENNDEIY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PANB_PSYA2
Sequence: MTTLSTLNKFKKDGTKFTCLTCYDAMFARMMEKAQIDTILIGDSLGMVVQGHDSTLPVTVDDMAYHTANVARSNKQALILADLPFMSYVTLPEAIANSRKLMQVGAHVIKIEGGSELCELVTMLAQAGTPTCVHLGLTPQSVNVFGGYKVQGRGDEAGQKLLDDAKAVVNAGAALLVLECVPAELAKAVTEAVAVPVIGIGAGADTDGQVLVMHDMLGMAHGRTPRFVHDFLTDERNTEHSIEGAFALYQQSVKEGSFPKEQHQFS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_CHLPD
Sequence: MTKEPVKGKGKTGNGNEQVLCSFCGRTTHEVNSMVAGPNAFICDRCIKTSYEILRKEISAINPSAKRAQESTFQTRLISPKAIMESLGQYVVGQEIAKKSLAVAVYNHYKRIDSQEWAHDSDEVVIEKSNILLIGPTGTGKTLLAQTLANLLDVPFTIADATSLTEAGYVGDDVETILARLLYASDFNLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVGVPPKGGRKHPEQQLININTRNILFICGGAFEGLDKLIARRVSKSSMGFGSKVKNKHTGYDPEILRFVTQDDLHEYGLIPEFIGRLPVISTLDPLDETALRSILVEPKNAIIKQYKKLFEMDGVELEFTDEALDKVVDIAIDRGTGARALRSVLESVMIDIMFELPTLKGVKKCVITADTIENRSEPEFYSGDGKKKKIA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: IHFB_RHILW
Sequence: MIKSELVQIVAARNPHLYHRDVENIVNAVLDEITDALAAGNRVELRGFGAFSVKNRPSRSGRNPRTGDTVFVEEKWVPFFKTGKELRERLNPGQADEED
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: EFGC_ARAHY
Sequence: NFSVFAMSADGDAKILYYTGRNKAIVWSGEELGAKLAQEDPSFHFSRVEANVGAPQVNYRQSGGQGQFADITVRFEPMDPGSGYEFKMLEPIMKRGQINSFGDKPGGLK
What is the function of this protein?
Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids.  Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, chloroplastic, cEF-G.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNMA_LIMRJ
Sequence: MADNSHTRVVVGMSGGVDSSVTALLLKRQGYDVVGVFMKNWDDTDENGVCTATEDYKDVAKVASKIGIPYYSVNFEKEYWDRVFKYFIAEYKKGRTPNPDVICNKEIKFKAFIEYANQLGADYVATGHYADVKRDENGRMHLMRAKDQHKDQTYFLSQLDYKQLDKVMFPLAGYTKPEIRKIAEEAGLATADKKDSVGICFIGEDGHFREFLSQYIPAQPGNMETLDGKVVGQHMGLMYYTIGQRRGLGLGGNKESNEPWFVIGKDMKKNVLYVGQGYENSHLYATHLEASDIHWVDDVVSRYGRDFHCTAKFRYRQTDVGVTVHLSDDDQMVTVEFDDPARAITPGQAVVFYDGEECLGSAIIDRAYSHDRQLQYV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCPR2_MAGO7
Sequence: MASKPGDFDAVRKDIVSLLDQPEYDDGSAGPVLVRLAWHSAGTYDKSTDTGGSNGAGMRYEAEGGDPANAGLQNARQFLEPVKARHPWITYADLRTLAGVVAVRAMGGPEIPWRAGRTDFADDSRVPPRGRLPDATQGAAHVRDIFYRMGFDDREIVALSGAHSLGRCHPANSGFEGKWVNNPTRFSNQYFRLLLSEDWREKTVAGTGLKQFVAVDEVTGDELMMLPTDLSLTSDPVFARWVKVYRDDQDLFFADFAKVFDKLMELGIKRDAEGKVINKENVEGGYVSAPKKQGKIASKL
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Putative heme-binding peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
Protein: ACEK_PSEE4
Sequence: MSQPWPAAEIARVILDGFDDYREHFRRITLGARERFEQARWQDIQRAAAARINLYEEKVAEVNGWLRKGFEGQVLLDVEQWPLVKNAYIRLIDPRLDDELSETWYNSLFCSLFSHDQISDGCMFIHTTRPSMRVHERAAQTRTYALTDRLKGLLRAIFADYAFDVPYGDLEADLSRLEEQLRECLPDWVCKDPQLKIELFTPVLYRNKGAYLVGRLYTPDEQWPLVIPLLHREGHGIEADALITDEAEVSIIFSFTRSYFMVDVPVPGEFVNFLKRILPGKHIAELYTSIGFYKHGKSEFYRALINHLANSDDRFVMAPGVRGMVMSVFTLPGFNTVFKIIKDRFSPSKTVDRATVIEKYRLVKSVDRVGRMADTQEFADFRFPQGKFDPECLAELLEVAPSTVSLEGDTVLIRHCWTERRMTPLNLYLEHASEGQVLEALEDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEISFLTEVNFRHIPPPRYPEDEMSGEPWYSIGPHDVFPEEFPPFLFADIGQRRLFSRLHGELYDADYWKGLQEAIRAGKVIDVFPYRRKSR
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMC3_SCHPO
Sequence: MYITKIVIQGFKSYKDYTVIEPLSPHHNVIVGRNGSGKSNFFAAIRFVLSDAYTHLSREERQALLHEGPGATVMSAYVEVTFANADNRFPTGKSEVVLRRTIGLKKDEYSLDKKTVSKTEVINLLESAGFSRSNPYYIVPQGRVTSLTNAKDSERLELLKEVAGTQIYENRRAESNKIMDETIQKSEKIDELLQYIEERLRELEEEKNDLAVYHKKDNERRCLEYAIYSREHDEINSVLDALEQDRIAALERNDDDSGAFIQREERIERIKAEITELNHSLELLRVEKQQNDEDYTNIMKSKVALELQSSQLSRQIEFSKKDESSKLNILSELESKISEKENELSEILPKYNAIVSEADDLNKRIMLLKNQKQSLLDKQSRTSQFTTKKERDEWIRNQLLQINRNINSTKENSDYLKTEYDEMENELKAKLSRKKEIEISLESQGDRMSQLLANITSINERKENLTDKRKSLWREEAKLKSSIENVKDDLSRSEKALGTTMDRNTSNGIRAVKDIAERLKLEGYYGPLCELFKVDNRFKVAVEATAGNSLFHIVVDNDETATQILDVIYKENAGRVTFMPLNKLRPKAVTYPDASDALPLIQYLEFDPKFDAAIKQVFSKTIVCPSIETASQYARSHQLNGITLSGDRSDKKGALTAGYRDYRNSRLDAIKNVKTYQIKFSDLQESLEKCRSEIESFDQKITACLDDLQKAQLSLKQFERDHIPLKDELVTITGETTDLQESMHHKSRMLELVVLELHTLEQQANDLKSELSSEMDELDPKDVEALKSLSGQIENLSHEFDAIIKERAHIEARKTALEYELNTNLYLRRNPLKAEIGSDNRIDESELNSVKRSLLKYENKLQIIKSSSSGLEEQMQRINSEISDKRNELESLEELQHEVATRIEQDAKINERNAAKRSLLLARKKECNEKIKSLGVLPEEAFIKYVSTSSNAIVKKLHKINEALKDYGSVNKKAYEQFNNFTKQRDSLLARREELRRSQESISELTTVLDQRKDEAIERTFKQVAKSFSEIFVKLVPAGRGELVMNRRSELSQSIEQDISMDIDTPSQKSSIDNYTGISIRVSFNSKDDEQLNINQLSGGQKSLCALTLIFAIQRCDPAPFNILDECDANLDAQYRSAIAAMVKEMSKTSQFICTTFRPEMVKVADNFYGVMFNHKVSTVESISKEEAMAFVEG
What is the function of this protein?
Involved in chromosome cohesion during cell cycle and in DNA repair.  Central component of cohesin complex.  The cohesin complex is required for the cohesion of sister chromatids after DNA replication.  The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
What are the official names of this protein?
Structural maintenance of chromosomes protein 3, Cohesin complex Psm3 subunit.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. At anaphase, the rad21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation.
Protein: NU5M_SHEEP
Sequence: MNLFSSLTLVTLILLTMPIAAINFNTHKFTNYPLYVKTTISCAFITSMIPTMMFIHTGQEMIISNWHWLTIQTLKLSLSFKMDFFSMMFVPVALFVTWSIMEFSMWYMHSDPNINQFFKYLLLFLITMLILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDIGFILAMAWFLINLNTWDLQQIFMLNPNDSNLPLMGLILAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFYPLTENNKFGQSIMLCLGAMTTLFTAMCALTQNDIKKIIAFSTSSQLGLMMVTIGINQPHLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGGLFKAMPFTTTALIIGSLALTGMPFLTGFYSKDLIIESANTSYTNAWALLMTLVATSFTAIYSTRIIFFALLGQPRFPTLININENNPFLINSIKRLLIGSLFAGFIISNNIPPMTIPQMTMPHYLKMTALTVTILGFILALEISNTTHYLKFNYPSNTFKFSNLLGYYPTIMHRLTPYMNLTMSQKSASSLLDLIWLETILPKTISLAQMKMSTTITSQKGLIKLYFLSFLITILISTTLLNFHE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DAPB_COCPS
Sequence: MGVEKRINDEEMQPLAERDDKSRDSIDSTSTASISLALLGGANGSAHGSRAARTRKSENQEKYHDDEEEGDLEEGFVPPAGGWSAPRKVSVIFTLIVTLCIAGWLVAFFVLLGRHKDSSKDAAVSQGESNIIPGIYSGGRGGKKLDLDGVLFGNWSPKSHDISWFPGPNGADGLLLEQGGDRNKAYLRVEDIRSRNPGNKADDTIVLMRESSFMVGKRLVRPSKVWPSPDLKTVLVMSDQRKNWRHSYTGNYWIFDVETQTGEPLDPESLDGGIQLASWSPNSDAIVFTRKNNMFIRRLPSKNVKQITTDGGTNLFYGIPDWVYEEEVFSDSSATWWDGDGKFVAFLRTNESRVPEYPVQYFIPNTNKPSRPSEENYPDIRKIKYPKAGAPNPVVNIQFFDVEKEEVFSVDVKDDLPDDDRLVIGVTWASNGNVLVRETNRESDRLSVVLIDAAKRAGKVVRSRNFSSLDGGWVEPSQTTHFVPADPKNGRPHDGYIETIPHDGFEHLAYFTPMDNSEPTVLTSGDWEVVDAPSAVDLKRGLVYFVAAKENPTERHIYTVKLDGSDLQPIVDTKSAGYYSISLSAGAGYALLKYEGPDIPWQKVISTPANEEKYEESIEKNPGLADMARKYALPSLHYQTITISGYELQVVERRPANFNPDKKYPVLFHLYGGPGSQTVTKKFKVDFQSYVASNLGYIVVTVDGRGTGFIGRKARCAVRGNLGHYEAIDQIETAKAWGKRSYVDAGRMAIWGWSYGGFMTLKTLEQDAGQTFQYGMAVAPVTDWRFYDSIYTERYMHTPQNNPEGYDRSAISNVTALDQAVRFMIVHGSGDDNVHIQNTLTLLDKLDLGSVKNFDVHVYPDSDHSIYFHNANKMVYQRLSDWLVNAFNGEWVKTRDPIPHKSLARRALGLINILRNG
What is the function of this protein?
Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Probable dipeptidyl-aminopeptidase B, DPAP B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Note=Lysosome-like vacuoles.