PharMolix/UniProtQA huggingface dataset:
Protein: RRF_KOCRD
Sequence: MISDVLSDATTRMGKAVDAAKTDFSTVRTGRANPALFSSLLVAYYGTPTPLQQLASFQTPEARTLLITPYDRSALNDIEKALRDSDIGANPANDGNVIRVVMPELTEERRKEYVKIVHGKAEDARVSVRNVRRHAKEAIEKLVKDGDVGEDDGKRGEKDLDAATKKHIDQVDELLKNKEAELLGA
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_VESOH
Sequence: MSNDYYLIIPAGGIGTRMHSEKDNINRKIKIAKQYLKLDNGLTILDQTLKILLNIDQIKGCIIALANKDYLFTKSKFNNHSKLITTVIGGKKRMNSVFNGLKALTNLAKDDDWILVHDSVRPCVKASEIINLMNQLKHHETGGLLATKVVDTIKQASNNIVNTTIDRSNLWQAQTPQMYRFGVLLKALNTVINDGMNITDEASAIEYLRLKSVLVKSSKSNIKITNSEDLELANFYLTQYKE
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: MDHC_PIG
Sequence: MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDVKNVIIWGNHSSTQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYGVPDDLLYSFPVTIKDKTWKIVEGLPINDFSREKMDLTAKELAEEKETAFEFLSSA
What is the function of this protein?
Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH.  Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation.
What are the official names of this protein?
Malate dehydrogenase, cytoplasmic, Aromatic alpha-keto acid reductase, KAR, Cytosolic malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_PSEAB
Sequence: MKTYTAKPETVQRDWFVVDAAGQTLGRLATEIARRLRGKHKPEYTPHVDTGDYIVVINAEQVRVTGAKTTDKMYYHHSGFPGGIKSINFEKLIAKAPERVIETAVKGMLPKNPLGRDMYRKLKVYKGASHPHTAQQPQELKI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RR12_NUPAD
Sequence: MPTIKQLIRNTRQPMRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VATB_PARUW
Sequence: MKIVYDRINNMRGNLITITAEGVSLGELARIDLKDGRNIYASVLRIDGDQVTLQVFQTTRGISTSDQVTFLNRQMQAVYGDTLLGRRLSGTGLPIDGGPQVIGESIDIGSTSFNPVKRIVPRDMVRTNIPMIDVFNCLVKSQKIPIFSVPGEPYNALLMRIANQTDADVVIIGGMGLTFKEYQAFIENAETAGTINKTVMFIHRATDPAVECLLVPDMALACAERFATDGKNVLVLLTDMTAFADAIKEIAITMDQVPSNRGYPGSLYSDLASRYEKAVSIEDSGSITVIGVTTMPGDDVTHPVPDNTGYITEGQFYLHHGKIDPFGSLSRLKQLVIGKVTRDDHGDLANAMIRLYAESKKARERQAMGFKLSKWDEKLLTYSHLFEERMMNLEVNYTLEEALDLGWETLAECFLASEVGIKESVISKYWPEIAQISK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CKP2L_MOUSE
Sequence: MVGPGPTASAAAEERWQKLQEYLAAKGKLKDPNAKPYLKAKNICPKPPPSKYTPGPKKDVSNHVLPSKTTRPINIKFQTKPASITASQKPESKPPKLPSRGLTSRCFSSNTDCKQSSKPQQQPRAVSFTAGLSRNPRQCPDIQELKTKQQQQAHGGNAKCTHPETNTHAAKQPVDGFPDETNKENLPQALPKPEKPDPELHSIRKPNTGSSNQTQKGLAPKQILSKSSVTQTALKDRANKQFIRNTQIRTQAVKSRPRPTVADSTRPREKPPQTAPSHSVPAHNKTQTSKKPMTKNTQDITVNRVRYGKPNETKIESCPATEQKVKHTKPSSQLNVLQGGHNSRHPNMRQDQKPVQPHLGPQTSCVLQKSRAISQRPNLTARNFNSVIPSTPNMRANKTLNNKYNNIFQQKAQTLDSKFRKFPPQSHFLNKTAPRTQASTAAASRKGAPSATQTHPHGKKPEGEDRRKQLEEWQKSKGKTYKRPPMKFKTKRKVIEEMNTSFWKSIEREEEEKKAQLELSKKIDSTLTECLRLIEEGVLPNEIFTIVSSIPEAEKFAKFWVCKAKLLASKGTFDAIGLYEEAIQNGATPVQELQEVLNVLQDPCRSTEAVTSDTSAAGTNTTSAEELAKEESEQPCPSLTEMEPIAAAAPRIPVSEWDNHGIKLQVAPIPRICGMPEVQDMKLITPVRRSARIERTVARYPEMLQEHDVVVASLNELLEVDKTECFIFRENEALPVTLGFEVLES
What is the function of this protein?
Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells.
What are the official names of this protein?
Cytoskeleton-associated protein 2-like, Radial fiber and mitotic spindle protein, Radmis.
What is the protein family that this protein belongs to?
Belongs to the CKAP2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle pole. Note=Uniformly distributed along each microtubule bundle of spindles in addition to centrioles during mitosis, expression promptly diminishes at interphase.
Protein: TOP1_STAAS
Sequence: MADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: HTPX_STRPN
Sequence: MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLVIALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFIIDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAVALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLVQLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKGGGFQKLFYTHPPISERIERLKQM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYR_NOVAD
Sequence: MTDATINLHADFARVIDAALDALEAAGTLPGTLSRSAVTCEPPRDPSHGDLATNAAMVLAKPAGTNPRALATALAAELEKEPRVVSAEIAGPGFINLRLTDDAWRGELALIGSAGADYGRSTMGGSKVVNVEYVSANPTGPMHMGHCRGAVVGDALADLLAFSGHQVIKEYYVNDAGAQVDVLARSVHMRYREALGETVEIPEGLYPGDYLVPVGKALAEEFGDKYAKAAEADWLILFRTRAVAAMMDMIRSDLATLGIHHDLFSSEAELQASGKVDAAEQWLRAHDLVYDGLLEAPKGKTPEDWEPVVLPLFRSTKFGDDQDRPIKKSNGAWTYFGADLAYHFQKAQTADALVDIWGADHAGTVKRIKAAVAALTSADGGTPKPFEVKLVQMVQLLRDGEPVKMSKRSGNFVTLSDVVEEVGKDVVRFTMLTRKPDAQMDFDFAKVVEASKDNPVFYVQYAHARICRNLRKGADEGFAPSSANLDLLGDEELALVKLAAQFPRTIEAAAAAREPHRIAFFLHDLASAFHSFYNLGNDRPDKRFIVAQDSAMTAARLFLAAQIGQVIRNGLAVLGVEAAQEL
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSLH_DICDI
Sequence: MNLKFYNLIFFISFLICCIHGQRYLPVEGGKCEKYIGDGDSGKRICNGYLANPDSVYVHNKTQQETLKDLRSLINLLELNNPSKECINPSNYKIMCAMMFPECIEINGTNIVKPITLPIYTCNSFCKEALVTCSVPNTIASCDGGTNLPIQLPYTPIEWVKYNLTIYGGVDDYRVNCTDPTLISDSGSSSEIEVGCVEPLIKRPTNDTKGDLEKGYFYVNSQCVINCPVTGMHPKSVWNQIFKINDVLSSISLACTLILLFTFGILNPKLNRFDKKNLFFIAGVFGMSVSGVLIAANGSEKTVCPTPERYAVNTDRVCVASGFLVHFSALFAILWWTIGLADVYYGIKFVGKKIKIKVRYYLLATLTISLAFTLVPLGTGQYQAGLSNVMCFLKDEIYQSMTFFVPLGICLTMGTILMILVMREIYVIVKSNSTSSSFSSSSSKSKSKSKSSDSISYLKLQVKPMLNIILFYFTFLYLFLFVRVINSRYQEYEDSAIPYMLCLAKGGGDSCRLKGPSAGSLGYFAYCLRIYGIYLFIISFLSSRTIKIWKESIILNNAFVTPIIKFIDSSFSNRFSSSKNTSTTQNSTLNNTESDTSKRGNSSAVSINLESRNYNTDDDDL
What are the official names of this protein?
Frizzled and smoothened-like protein H.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FB170_ARATH
Sequence: MHLPEDLVLEILSKVPAVSLARFRSTCRRWNALVVDGSFAKKHYAYGPRQYPIVIMLIEFRVYLVSIDLHGINNNNGAPSAKLTGQFSLKDPLSNSSEEVDIRNAFHCDGLLLCCTKDRRLVVWNPCSGETKWIQPRNSYKESDLYALGYDNRSSSYKILRMHPVGNPFHIESEVYDFASHSWRSVGVTTDFHIQTNESYGMNVKGTTYWFALSKDWWSSDDRRFLLSFDFSRERFQCLPLPADVKNLHLTVVLSVTREEQQLCMFATLGAGNVYKLDVFVATKTEETTGELTWTKFRRFHSKICINVSADHEKKVLVPHHILLPYYNILHIVGEDIYIRQVNKDGDIGCPILLTYVPSLVQIQQGI
What are the official names of this protein?
Putative F-box protein At3g21120.
Protein: RL24_STAAM
Sequence: MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIKSNN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RUVB_SYNSC
Sequence: MAIVSSSSGRKPPRRPEALMDPQQAPEEVVSRPEDKLRPQRLDDYIGQSELKQVLGIAVQAALGRGDALDHVLLYGPPGLGKTTMAMVLAEEMGVHCKVTSAPALERPRDIVGLLVNLQPRDLLFIDEIHRLSRVAEELLYPAMEDRRLDLTVGKGSTARTRSLDLPPFTLVGATTRAGSLSSPLRDRFGLIQRLEFYGQGDLEAIVERTAGLIGVTLTPQARSSIAASCRGTPRIANRLLRRVRDVASVRGGGGGAINQALVGEALSLHRVDHRGLDASDRRLLQLLIDHHGGGPVGLETLAAALGDDPVTLETVVEPFLMQQGLLMRTPRGRMVTDAARSHLAEAA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RL3_RALSO
Sequence: MSLGLVGRKVGMTRVFTDDGDSIPVTVLEVGGNRVTQIKTDETDGYTAVQVTFGTRRASRVTKPLAGHLAKAGVEAGEIIVEFRIDATKAAELKLGDTIDVDLFSVDQKIDVQGTTIGKGYAGTIKRYHFSSGRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHMGDVTRTVQNLVIVRIDAERKLLLVKGAVPGAKSGFVVVSPAVKAKPQVAAAA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: COFG_SYNY3
Sequence: MLSITYSPAYTLVPTYECFNRCSYCNFRQEPRKDQWLTESVAKQRLESLAGRGIREILILAGEVHPQSSRRKAWFELIYNLGKIALDLGFYPHTNAGPLSRSEIARLKEVNFSLGLMLEQVSPRLLTTVHRQAPSKEPQLRLEQLRLAGELGIPFTTGLLLGIGETDQEVEESLMAIANVQQEYGHIQEVILQPHSPGQKQTDNISAYSPQKLVQVITLARAILPAEITLQIPPNLVPNFSDLLACLAAGVRDLGGIVPIDEVNPDYHHQSVNQLSQLLEENGYLLQPRFPVYPTYFSWLNCDLQQRLSVFIN
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: DNLJ_ELUMP
Sequence: MDKIKKEIEDLRSKINYHNNLYYNLDNAEISDAEYDGLYARLKFLEAMNPDYADAASPTQKIGGAASRVFTSVTHASQMMSLDNTYSSEEVLRWHERCVKSLGHGNFEMVAEAKIDGVSCSLTYEGGVLTVAATRGDGKTGEDVTANIKTIKTIPHNISFKNKIEIRGEIYIEKADLKRLNEIQENEGENIFANTRNAAAGSIRQKNAEISASRPLKFFAHSFGYGDVDVKGFAEFMDLCKSWGFSVTPNRIRTADINEITSFYKRFEELRAGLPYDVDGIVVKINSFAEQKILGVTAKSPRWAIAFKYKPPQGKTVVNKIIFSVGRTGIITPVAELEPVAVAGVIISNATLHNFDEIKRLGVKEGDTVIVERAGEVIPKILNVVKDGGGNEVKAPKNCPSCGSKVYRYEDEVAIRCINPACPAQIKGHLLHFVSRAAMDIDGFGEAVVEQVVEKKYVKDFADIYNLKAEQLLTLDLFKDKKVNNLLLAVEASKKRSLSRVLYAFGIRHVGQKTGEILANHFEDIENMLAASLEDFQKINEIGPVVGQSVYDFMQSAKGKEEIARLKTAGVNFTQPKVQLAGNELLGKTLVFTGELNMPRTQAEALAKAHGGKVSGSVSSKTSYVVAGADAGSKLTKAQSLGVSVISEEEFLNLIK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LIPB_PELUB
Sequence: MNIEIKKSIKPIKYEDAIKLLEERLLEINNGQKEDLIWILEHEEVYSAGTSYKEKEILNKDISLVKTNRGGKITYHGPGQLICYFVIDLKKRKKDIRKFITLIEETIIDSLSKFNIKTFGDPKNIGIWTDHKGKINKVAAIGVRVSKWIAYHGFAININNDLSKYKNIIPCGISDKGVINLKEIKDQDYKNLDEIIIETFSKNLEI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNR_ECO57
Sequence: MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLGVPLFDRSGRTIHLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPGITLQLQEMSQEKIEDLLCRDELDVGIAFAPVHLPELEAIPLLTESLALVVAQHHPLAACEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVVIEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAIPLAPPLLERTAVLLRRKNSWQTAAAKAFLHMALEECADVGENESR
What is the function of this protein?
Positively regulates the cynTSX operon, and negatively regulates its own transcription.  Binds specifically to the cynR-cynTSX intergenic region (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator CynR, Cyn operon transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGD_XANC8
Sequence: MSSRYTPSEMAQALGAGLLSFPVTHFDADMAFDEPAYRSNLDWLSSHPAAGLFAAGGTGELFSLTLDEVDRAVRAAVTQTAGRMPVIAPAGYGTAIAVAMAQAAERNDADGILLFPPYLTECDADGVAEHVERVCKATSLGVIVYGRANARLDDVALARVAERCPNLMGYKDGIGDVDRMTRIYARLGDRLLYVGGLPTAETFALPYLEMGVTTYSSAIFNFLPEWALSFYAAVRARDHATIYRELNDFVLPYTVLRNRRAGYAVSIVKAGMRAVGRPAGPVRTPLADLTEDEFAQPTQLIGGRR
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: ACD11_RAT
Sequence: MEMDVTRDTVEVLPQHKFDIRSLEAYLNQHLPGFGSDHRAVLTVTQYRSGQSNPTFFLQKGSQAYVLRKKPPGSLLPKAHKIDREFKVQKALFSVGFPVPKPLLYCSNASIIGTEFYVMEHVQGRIFRDFSIPGVSPAERAAIYVSLVETLAWLHSLDIHSLGLDRYGTGVGYCKRQVSTWTKQYQASAHQSIPAMDQLSTWLMRNLPDSDNEECLVHGDFKLDNIVFHPKECRVIAVLDWELSTFGHPLSDLAHLSLFYFWPRTLPMINRGSHIQENTGIPLMEELISIYCRRRGIDPNLPNWNFFMALSFFKLAGIAQGVYSRYLMGNNSSEDSFLTANTVQPLAETGLQLSRRTLSTVPPQADAKSRLFAQSRRGQEVLTRVKQFMKQHVFPAEKEVAEYYAQNGNSAEKWEHPLVIEKLKEMAKAEGLWNLFLPAVSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKQQWLEPLLRGDITSVFCMTEPNVSSSDATNMECSIQRDGGSYIVHGKKWWSSGAGNPKCKIAVVLGRTESPSVSRHKVHSMILVPMDTPGVELIRPLSVFGYMDNVHGGHWEVHFNHVRVPASNLILGEGRGFEISQGRLGPGRIHHCMRSVGLAERILQIMCDRAVQREAFGKKLYEHEVVAHWIAKSRIAIEEIRLLTLKAAHSIDTLGSAAARKEIAMIKVAAPKAVCKIADRAIQVHGGAGVSQDYPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQARQLKARM
What is the function of this protein?
Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA.  Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain.
What are the official names of this protein?
Acyl-CoA dehydrogenase family member 11, ACAD-11.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome. Mitochondrion membrane.
Protein: RSMH_RICTY
Sequence: MSQYHIPVMLSEVLEVLAPKGYESYLDCTFGAGGYSNAILKSCYCSVTSLDCDPHVIERVEQIKQDYGERFSFIKTNFADSFGKLKQQKFDGIVMDLGVSSMQLDIAGRGFSFLYDGPLDMRMSAQGFSAEEFVNTADEEEISDVIYKYGNESLSRRIAKNIIKYRKIARIDSTRKLAEIVRYSIGFRKGKIDSATKTFQAIRIYINNELGELERFLANVKNILKKNGRLVVVSFHSLEDRIVKNFFKENSAKPVARSKYAKDEIKIDQNKWLEIITHKVLTPSSQEIRLNVRARSAKLRAAKKIL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_CUTAK
Sequence: MTATTITPETKDEVVGVGRVVRVIGPVVDVEFPAGQLPEILNALHVDAEVMGETHAITLEVALHIGENVVRAISLKPTDGMRRGTEVRDTGAPISVPVGDVTKGHVWNVTGDVLNADPSTIEVTERWPIHRDPPAFDDLEPETEMLETGIKVLDLLTPYVKGGKIGLFGGAGVGKTVLIQEMIYRIAHNFGGTSVFAGVGERTREGNDLINEMDEAGVLKDTALVFGQMDEPPGTRLRIALTGLTMAEYFRDVQNQDVLLFIDNIFRFSQAGSEVSTLLGRMPSAVGYQPNLADEMGQLQERITSTRGHSITSMQAVYVPADDYTDPAPATTFAHLDATTELSREIASRGLYPAVDPLTSTSRILDPLYVGQEHYDTATQVKQILQRNKELQDIIAILGVDELSEEDKVTVARARRIQQFLSQNTYTAEKFTGVAGSTVPIADTVEGFQMICRGDVDHIPEQAFFNVGSMDMVMENWDKMKKEG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AROE_SHEB2
Sequence: MTDRYAVFGNPISHSKSPFIHGQFAAPTQESLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSISPEAKLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQDQRVLLIGAGGAARGCILPLLNAEIAQLTISNRTHTKAQLLVDIFTSVDNGAYASKVTAVEMSELAGEFDIIINSTSASLAGELPPLPAHIITTQTVCYDMMYGASITAFNQWALSQGAAKVIDGLGMLVGQAAKSFTLWRGIEPDTQVVLTLLRDKLMAEPK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: TAL_PSEMY
Sequence: MTSKLEQLKQFTTVVADTGDLDAIARLKPVDATTNPSLLLKAASLPGYADLLKQAVSTGKGDPGLACDHFAVAVGQEILKVIPGRISTEVDARLSFDTGATLLRAERLIGLYEQAGIGRERVLIKIASTWEGIRAAEQLEKSGVQTNLTLLFSFAQAQACADAGVFLISPFVGRIYDWYKKTEGRDFVGSEDPGVQSVSRIYDYYKANGYDTVVMGASFRNLGQIEALAGCDRLTISPELLQKLAEDEGELSRKLAPGGAGEARQTLDESAFRWALNEDAMATEKLAEGIRLFARDQEKLEALLAAKA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB_SHIB3
Sequence: MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGAMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMDIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAESRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVALDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.