PharMolix/UniProtQA huggingface dataset:
Protein: AT222_ASPCL
Sequence: MRADDNPSARSLHAQFPGDDTRPTSKKELAGWYSYGWAAEVFTVCAMGSFLPITLEQMARDRGVLLSDKVTPCSASWNGTETTARTHGISPPWYGINATPGTSQCVVYILGAEINTASFAMYTFSVSVFVQAVLIISMSGAADHGSFRKTLLVAFAVIGSVCTMLFLSVVPKIYIVGALFAIVANTCFGASFVLLNSFLPLLVRHHPSLLGHENERSPELNHSHITDDRVQFAANADYGIDADATSPLLQPVQGDSDEHTTSRLPVTSVVISEELKLSTRISSLGIGIGYIGAVILQIICILVIIATRQTTFSLRLVLFLIGLWWFVFTIPAALWLRPRPGPPLPKAPQGKDNRSCVGYMVYAWKSLCRTAVRTRHLKDILLFLTAWFLLSDGIATVSGTAVLFAKTQLNMKPAALGLINVVTMMAGVFGAFSWSFVSRRLNLGASQTIIACILLFELIPIYGLLGFVPAIRKLGYLGLQQPWEMFPLGIVYGLVMGGLSSYCRSFFGELIPPGNEAAFYALYAITDKGSSIFGPAIVGLITDRYGEIRPAFVFLAVLIFLPLPLMLLVDVGRGKKDALALAVELEEGQSSNTQTYGTLSNCERNAVPTDQ
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22-2.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: DERL1_ORYSJ
Sequence: MSSPAEYYNSLPPISKAYGTLCFFATVLCQLQILNPPFLALYYPFVFKKFQIWRLFTSFFFLGKFSINFGIRLLMIARYGVQLEKGAFEKRTADFLWMMIFGAISLLALSAIPFLDIYFLGVPMVSMLLYVWSREYPNSQISMYGLVQLRSFYLPWAMLGLDVIFGSEILPGLLGILVGHTYYFLSVLHPLATGKNYLKTPMWVHKIVARFRIGVQANAPVRPAAANTGSGAFRGRSYRLSQ
What is the function of this protein?
May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins.
What are the official names of this protein?
Derlin-1, 18 kDa cold-induced protein, DER1-like protein 1, OsDerlin 1-1.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PUR9_STRSU
Sequence: MTKRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGRVKTLHPKIHGGLLARRDLDSHLQAANDHEIGLIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYPTVLGEIAEQGETSYATRQRLAAKVFRHTAAYDALIADYFTKQVGEDKPEKLTITYDLNQPMRYGENPQQNADFYQNALPTAYSIAAAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHMNPCGIGQAETIEQAWDYAYEADPVSIFGGIVVLNREVDAATAEKMHPIFLEIIIAPGYSAEALAILTNKKKNLRILELAFDAQDASEVEKEFTGVVGGLLVQDQDVVVESPVDWQVVTERQPSEQEWAAMEFAWKSSKYVKSNGIIITNDKMTLGVGPGQTNRVASVRIAIEQAKDRLEGAVLASDAFFPFADNVEEIAAAGIKAIIQPGGSVRDQDSIDMANKYGLTMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SAC1_PONAB
Sequence: MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLIVITKKIKVGEFFSHVIWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID
What is the function of this protein?
Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 3-phosphate (PtdIns(3)P) and has low activity towards phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).  Shows a very robust PtdIns(4)P phosphatase activity when it binds PtdIns(4)P in a 'cis' configuration in the cellular environment, with much less activity seen when it binds PtdIns(4)P in 'trans' configuration (By similarity).  PtdIns(4)P phosphatase activity (when it binds PtdIns(4)P in 'trans' configuration) is enhanced in the presence of PLEKHA3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol-3-phosphatase SAC1, Phosphatidylinositol-4-phosphate phosphatase, Suppressor of actin mutations 1-like protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Trafficking between the ER and Golgi is regulated by nutrient status and by TMEM39A. Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS) in the presence of phosphatidylinositol-4,5-bisphosphate.
Protein: RL14_BORAP
Sequence: MIQMQTYLTIADNTGGKVAQCIKVLGGSKRRYAKIGDIITIVVKQAIPNSSVKKGDVCKAVIVRTSKEVRRKNGTYVRFDDNACVILDANLSPRGKRVFGPVARELRDANFMKVVSLASEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HEM3_DEBHA
Sequence: MPHNTKSMDNTLNIKDNHVQIGGRKSKLAVVQSEIVKECIVEKFPELSCSVLALSTLGDKVQSKPLYSFGGKALWTKELEILLLEQVEEYPRLDLIVHSLKDIPTNLPEEFELGCILNREDARDALVMKSGSSYKSLADLPDGSLVGTSSVRRSSQLLKNHPKLRFDSVRGNLQTRLNKLDDENSPFECLLLASAGLIRIGLGDRITAHLDAPEMYYAVGQGALGIEIRKGDEKMLQLLKTIEDLPTTYCCLAERSLMRHLEGGCSVPIGVQSHYNESTNELSLKAIIVSPDGIHFVEDEYKGVVNNKDDADAIGIKVGDLLSAKGGREILNSINFERINLPPSSNTPTPQPITPITTNNS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RLMF_PSEF5
Sequence: MTAPSTPKPSRKKPKPASPAKPATPREKASLHPRNRHQGRYDFPQLIKSTPELGQFVILNPYGKESIDFADPAAVRVFNRALLKAFYGIAHWDIPADFLCPPVPGRADYVHFLADLLASHNQGEIPRGAAVRVLDVGVGANCIYPLIGYSDYRWQFLGSDIDSTALAAAKAIVQANDLNKAISLRQQGNPKQILTGLLDSTERFDLTMCNPPFHASLDEATRGSQRKWRALGKADPKRKLPVLNFGGQARELWCEGGEIRFVSQLISESASVGQQVLWFSTLVSKASNLPAIESALKKAGALESQVVEMSQGQKQSRFVAWTFKDKAQQQAWSQERWMRKN
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_RHOP2
Sequence: MTRPVVTRFAPSPTGFLHIGGGRTALFNWLYARKLGGKMLLRIEDTDRQRSTQPAIDAILDGLKWLGIEWDGDTVYQFARAARHREVAEQLLAAGKAYRCYATAEELTAMRDKARAEGRSKLYDGSWRDRDPSEAPADMKPTIRLKAPLDGETVIEDQVQGRVVWQNENLDDLVLLRGDGTPTYMLAVVVDDHDMDVTHVIRGDDHLINAARQKQIYDAMGWELPVMAHIPLIHGPDGSKLSKRHGALGVDAYRAMGYLPAALRNYLVRLGWSHGDQEIFTTQEMIDAFDLAAIGRSAARFDFAKLESLNGHYIRQSDDQSLVTLLEDLLHYVPQGPAIAARLTDTTRAQLVQAMPGLKERAKTLLELLDNAGFIFADRPLAIDAKGQAVLTPDIRALIGRLRTALEDVSPWTAATTEAAMRTFAEQAGLKLGAVAQPLRVALTGRTTSPGIFDVLAVLGREECLSRLADQAA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAF1_RAT
Sequence: MEVVEAAAQLQTLKFGGSGPGSAASPPPEERPDAEQAEQAPPAGEQPPPAPSSDAGENPPPPSGPCATAPDAAEPLPELQDSDSSDSDSDSETDSDSSSSSSSSSSSSSSCGSLPPVLSDGEEDVQVEKENKNFPLKTKDELLLNELPSVEELTVTLPEDIALKPLGKVSSIIEQLVIIESMTNIPPVNEDTVIFKSDRQAAGKIFEIFGPVAHPFYVLRFNSSEHIESKGIKIKDTMYFAPSMKDFTQYIFTEKLKQDRGSDASWKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSELNESGEDFGEVHQNWNANSSSEHSKGYHNREFTRGFPRGRYSRGSHGRPPPQQYYNSDPMASQESLGFPPQRQDNPVMPHYPFPPPMFDMHNFPLPPPPPPPPTVSMGWAAPSMTSHPVLNLPYSLPPPPLPPPPPPPSPGESNSSHFGSYY
What is the function of this protein?
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis.  During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex.  Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4 (By similarity).
What are the official names of this protein?
H/ACA ribonucleoprotein complex non-core subunit NAF1.
What is the protein family that this protein belongs to?
Belongs to the NAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus. Absent from the nucleolus (By similarity).
Protein: SHSA5_HUMAN
Sequence: MTAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSDVLKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSVVTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMPPQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL
What is the function of this protein?
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
What are the official names of this protein?
Protein shisa-5, Putative NF-kappa-B-activating protein 120, Scotin.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane.
Protein: ISK14_RAT
Sequence: MVKYFQVLWSLLFSIMLHSMLLAAPGARVWWPTHGLIKIKCPYKKVKLSWFNKTVDPCPGLKQPICGTNFVTYDNPCILCVESLKSGGQIRYYHTGRC
What is the function of this protein?
May be a serine protease inhibitor.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 14.
What are the subcellular locations of this protein?
Secreted.
Protein: THIC2_SYNC1
Sequence: MTQLEMARQGIVSDKMKQAAADAGIDAEILRQRIAEGTAIVCHNNMHANGRPLAVGKGLPTRVNANIGTSKDDTSIDNELEKARVAVAAGADAIMDLSTGGPIDEIRRAIIAETQACIGSVPLYQAACDTVVKKGKAIVDMTADEIFDGIKKHLDDGVDFITVHCGVTLSTVERMDNEGRIMDVVSRGGSFTVAWMTHNNAENPLYEQYDRLLELVKPYDATLSLGDGFRPGCLADATDRAQIHELIILGELTQRAWDAGIQVMIEGPGHVPLNQIEANIQLQKSLCHGAPFYVLGPLVTDIAPGYDHITCAIGGAVAAGAGADFLCYVTPSEHLCLPNVQDVHDGVMATRIAAHAADIVKGLPGAMEKDIAMSKARKGLDWETQYCLAIDPELARKRRGESGVDEEHGACTMCGEFCAYKVMDERKPKQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase 2, Hydroxymethylpyrimidine phosphate synthase 2, HMP-P synthase 2, HMP-phosphate synthase 2, HMPP synthase 2, Thiamine biosynthesis protein ThiC 2.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RL21_OCEIH
Sequence: MYAIIETGGKQIKVVEGQEIYVEKVTADVNESVTFDKVLFIGGDDVKVGAPLIDGATVTAKVEKHGRQKKIDVHKFKPKKNYHRKQGHRQPYTKLVIDKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GCNT4_MOUSE
Sequence: MKIFRCCFKYTLQQKLFILLLTLWLFSLLKLLNVGRLLFPQRDIYLVEYSLSTSPFVRNRFPESGDAARDNVNCSGVYEHEPLEIGKSLEIRRRSIIDLEDGDVVAMTSDCDVYQTLRQYHEKLVSREEEDFPIAYSLVVHKDAIMVERLIRAIYNQHNLYCIHYDLKSPDTFKAAMNNLAKCFPNIFIASKLETVEYAHISRLQADWNCLSDLLKSSVQWKYVINLCGQDFPLKSNFELVTELKSLQGRNMLETVRPPSAKTERFTYHHELRQVPYDYMKLPVKTNVSKGAPPHNIQVFVGSAYFVLSRAFVKYIFNSSLVEDFFAWSKDTYSPDEHFWATLIRIPGIPGGISSSSQDVSDLQSKTRLVKWFYYEGFLYPNCTGSHLRSVCIYGAAELRWLLNEGHWFANKFDSKVDPILMKCLAEKLEEQQRKLIALSSEKFMTEGTRQSHTL
What is the function of this protein?
Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis.  Does not have core 4 O-glycan or I-branching enzyme activity.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4, Core 2-branching enzyme 3, Core2-GlcNAc-transferase 3, C2GnT3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RL27_STRZP
Sequence: MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SPK1_GIRTI
Sequence: MGQKFSIKCKKQSKNKNTSKCQKIPKKAYEGPPGSYMVKAKYKYAASGDTDISFEEKEIMYVLEQFDEFWLKVVKQKDNKEGLVPSNYVSKQDGSPQSVEAWREIQRWEAEKSLMKIGLQKGTYIIRPSRKENSYALSVRDFDEKKKICIVKHFQIKTLQDEKGISYSVNIRNFPNILTLIQFYEKNGIGNTHIPLTDPMPDNYQPPVHFQDIEINRENIEILNEIGRGFFGSVHRAKWGRSYEVAAKMLQSSKAEREKFVLEAKIMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADNILVANDLTRKVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILTWASSPYPDIPAKEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKMDLLIVDTLTNNAYYSHSK
What are the official names of this protein?
Tyrosine-protein kinase SPK-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
Protein: PLIN2_PIG
Sequence: MASVAVESQPSVVTRVANLPLVSSTYDLVSSAYISTKDQYPYLKSLCEMAEKGVKTITSVAMSGALPIIQKLEPQIAIANTYACKGLDRIEEKLPILNQPTNQVVANAKGAVTGAKDAMTTTVTGAKDCVASTITEVVDKTKEAVTGSVEKTKSVVNGSINTVLGGRMMQLVSSGVEKAFTKSELLVDQYLPLTEEELEKEAKKVEGFDMVQKPSYYIRLGSLSTKLRSRAYQQALTRVKEVKQKSQETISQLHSTVNLIEFARKNVHNANQKIQGTQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLVSNIQGLPQNIHDQANHLGVMAGDIYSVFHNASSFKEMSDGLLSSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQDAQSRGAENTTSPETQQPETKRIKPAPASSAWGSQSGDTSCTVATC
What is the function of this protein?
Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.
What are the official names of this protein?
Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP.
What is the protein family that this protein belongs to?
Belongs to the perilipin family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Lipid droplet.
Protein: MNTH_XANCP
Sequence: MSSEIVPIAEPIRPADGGLGAAHASVAVPKGGHWWFRLLAFLGPGYMVSVGYMDPGNWATDLAGGSQFGYLLLSVILLSNLMAIVLQGLSARLGIATGLDLAQACRARYPRGINLALWGLCELAIIACDLAEVIGTAIALKLLFGIPLTLGAIITALDVVLVLLLMNRGFRALEAFVMALLLVIFVCFGIQIALAAPPIAAVLAGFIPRAEVVTNPHALYLAIGIIGATVMPHNLYLHSSIVQTRAYPRTDAGRRSALRWAVTDSTVALMFALFINAAILILAAAVFHAQGRTDVQEIEQAHALLAPMLGVGLASTLFAVALLASGVNSTVTATLAGQIVMEGFLRLRLPPWMRRLLTRGIAIVPVVVVTWLYGEAGTARLLVLSQVVLSMQLPFAVIPLVRFVADRGLMGALVAPAWLVRLAWVIALVIVGLNLKLLWEFALG
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UXAC_EDWI9
Sequence: MSPFLTEDFLLDTEFARRLYHDYAEEQPIFDYHCHLPPEQIAENYRFKNLYDIWLKGDHYKWRAMRTNGVAECFCTGEASDREKFQAWAETVPHTIGNPLYHWTHLELRRPFGITDTLLSATTAEDIWTRCNRMLAEDSFTARGIMGQMNVKMVGTTDDPIDDLRHHRTIAADSSFTTKVLPSWRPDKAFNIEAALFSDYIVKLGAVADVDITRFADLCQALKVRMDHFAAHGCKVSDHALDVVVYGEADDATLDGILARRLSGGTPGEIEVAQFKTAVLLFLGCEYRRRGWVQQYHIGALRNNNTPMFERLGPDIGFDSINDAPVAQPLSRLLDAQSRNGGLTKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMQRQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVAQGEAPADIALLGSMVKNICFDNAKSYFAIEL
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: HLDD_BORBR
Sequence: MIVVTGAAGFIGSNLVRGLNRRGIQDIIAVDDLTDGDKFRNLVDCSIADYLDKDEFRERVRGGNLPALRAVLHQGACSDTTERNGRYMLDNNYRVTLELFEYCQAERVPFLYASSAAVYGGSSVYVEDPANEHPLNVYGYSKLLFDQVLRTRMDSLTAQVVGLRYFNVYGPHEQHKGRMASVAFHNMNQFLAEGHVRLFAGWDGYEDGGQSRDFISVEDVVAVNLHFLDNPGQSGVFNCGTGRAQPFNDVAAAVVNTLRAERGEAALPLAELVKKGLLRYIPFPDDLKGRYQSYTQADVGRLRAAGFSAPMRDVQTGVSEYVRYWRALK
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: FIS_PECCP
Sequence: MFEQRVNSDVLTVSTVNSQAQVTQKPLRDSVKQALKNYFAQLNGQDVSDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: PURT_SHIBS
Sequence: MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEERLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWKYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCSDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQNVTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: SYH_DECAR
Sequence: MSQTLQAVRGMNDVLPDEAEFWELFEDTIRSWLKGYGYRPIRMPIVEPTPLFKRAIGEVTDIVEKEMYSFVDGLNGEALTLRPEGTAGCVRAVIEHNLAARQTQRLYYIGQMFRHERPQKGRYRQFHQVGVESFGMAGPDIDAEMILMGARLWADLGLDGIELQLNSLGQPEERALHRAALITYFEENAELLDEDAKRRLHTNPLRILDTKNPAMQELCAAAPKLIDYLGAESLAHFEGVQRVLRDAGVPFTINPRLVRGLDYYNLTVFEWVTDKLGAQGTVCAGGRYDGLVEQLGGKPTPACGFAMGVERLIALIRESGGEPAAPAPDVYLVHQGEAAARQAFRVAEGLRDQGINVLQHCGGGSFKSQMKKADGSGATFAVIIGDDEAATGEAQLKSLRAEGSAQLKLKVDDLAEAIIGQLIDSDEEE
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNGA4_MOUSE
Sequence: MSQDSKVKTTESTPPAPTKARKWLPVLDPSGDYYYWWLNTMVFPIMYNLIIVVCRACFPDLQHSYLVAWFVLDYTSDLLYLLDIGVRFHTGFLEQGILVVDKSMIASRYVRTWSFLLDLASLVPTDAAYVQLGPHIPTLRLNRFLRVPRLFEAFDRTETRTAYPNAFRIAKLMIYIFVVIHWNSCLYFALSRYLGFGRDAWVYPDPAQPGFERLRRQYLYSFYFSTLILTTVGDTPLPAREEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTADAAFYPDHALVKKYMKLQHVNRRLERRVIDWYQHLQINKKMTNEVAILQHLPERLRAEVAVSVHLSTLSRVQIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGREMYIIREGQLAVVADDGVTQYAVLGAGLYFGEISIINIKGNMSGNRRTANIKSLGYSDLFCLSKEDLREVLSEYPQAQAVMEEKGREILLKMNKLDVNAEAAEIALQEATESRLKGLDQQLDDLQTKFARLLAELESSALKIAYRIERLEWQTREWPMPDDMGEADDEAEPGEGTSKDGEEKAGQEGPSGLE
What is the function of this protein?
Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs).  CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation.  By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
What are the official names of this protein?
Cyclic nucleotide-gated cation channel alpha-4, Cyclic nucleotide-gated channel alpha-4, CNG channel alpha-4, CNG-4, CNG4.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GCST_PORGI
Sequence: MKTTPFTDVHIALGAKMHEFAGYNMPIEYGGIIDEHMNVVNNVGVFDVSHMGEFWVKGPNALRFLQKVSSNDASKLAVGQVQYCCFPNNDGGIVDDFLLYRYEEEKYMMVPNAANIAKDWAWCRQQNTMGAILENASDNIAQLAVQGPKATEVMQRLTDIDLNEITYYTFKVGSFAGCPDVIISATGYTGAGGFELYFYPQYAQKIWDALFEAGKPEGIKPAGLGARDTLRLEMGFCLYGNDICDTTSPIEAGLGWITKFTDDKMDMPSRKIMEEQKAGGLKRKLVAFELKDKGIPRQHYEIANAEGQIIGEVTSGTMSPCLKKGIGMGYVATEFSKVGTELGIMVRGRQLKAEIVKPPFRK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: SYI_PROM9
Sequence: MKSQNNKEYKSEFSYKETLNLLKTDFSMRANSVLREPEIQNFWAKNNIDFELGSNNSGKIFTLHDGPPYANGALHMGHALNKVLKDIINKYKTLRGFRVHYVPGWDCHGLPIELKVLQNLKSSERKNLDTLNLRKKATDYAYVQINNQMEGFKRWGIWGNWDNPYLTLKKSYESAQIGVFGKMFLNGYIYRGLKPVHWSPSSRTALAEAELEYPDEHYSKSIYVSLKITKLSDEILLKFYQENPNFKKDFFLSNSFITIWTTTPWTIPANEAVAVNPKINYVFAIDEEKRIYLLAKELSSEISNKFNKDLTTLLEVKGVTLEDIEYQHPTKNKNCRIVIGGDYITIESGTGIVHTAPGHGIDDFNVGRKYDLPTTCVVDEKGNLNEYSGQFQGSNVLKDANDLIIDYLEEKDLLLLQENYKHRYPYDWRTKKPTIFRATEQWFASVNGFRSSALKAIEDVEWIPATGKKRIYSMVVGRGDWCISRQRSWGLPIPVFYKKNGNEILLNSEIINHIQKLFSEHGADIWWDWDVKHLLPDNYVKESDLWKKGTDTMDVWFDSGSSWAAVCEQRSELKYPADLYLEGSDQHRGWFQSSLLTSVAVNNKPPYKKVLTHGFALDENGRKMSKSLGNVVDPNIIINGGNNKKIEPAYGADVLRLWVSSVDYSVDVPIGSNILKQLSDVYRKVRNTARYLLGNIHDYDPNIDSFEIDQLPLLDQWMLGRLVEVTDQISNAYENYEFSKFFQILQSFCVVDLSNFYLDIAKDRLYVSSKSQFRRRSCQFVMSKVVENLAVLISPVLCHMAEDIWQNVPYSTKEKSVFQRGWPNFSQSWKNEILNEHIANLRNLRVEINKAIEGCRNKQIIGAALETEVNYLPKDKVVKDSLTWLKKFGNEEVDLFRDWLIVSNFQVVSELAKNSLIIDNNEIGKIQILKAHGQKCDRCWHYQEEIFSGIQNTKLCKRCSHIINLEFT
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL119_HCMVA
Sequence: MCSVLAIALVVALLGDMHPGVKSSTTSAVTSPSNTTVTSTTSISTSNNVTSAVTTTVQTSTSSASTSVIATTQKEGHLYTVNCEASYSHDQVSLNATCKVILLNNTKNPDILSVTCYARTDCKGPFTQVGYLSAFPPDNEGKLHLSYNATAQELLISGLRPQETTEYTCSFFSWGRHHNATWDLFTYPIYAVYGTRLNATTMRVRVLLQEHEHCLLNGSSLYHPNSTVHLHQGNQLIPPWNISNVTYNGQRLREFVFYLNGTYTVVRLHVQIAGRSFTTTYVFIKSDPLFEDRLLAYGVLAFLVFMVIILLYVTYMLARRRDWSYKRLEEPVEEKKHPVPYFKQW
What is the function of this protein?
Serves as a receptor for the Fc part of human IgG.  May thus be involved in interfering with host Ig-mediated immune responses.
What are the official names of this protein?
Viral Fc-gamma receptor-like protein UL119, gp68.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.