PharMolix/UniProtQA huggingface dataset:
Protein: QUEF_GRABC
Sequence: MAENYAGLTQLGQTVSQPASPDQAVLEKVPNPTPGKAYMIRFTAPEFTSLCPLTGQPDFAHIVLDYVPRDWIVESKSLKLFLTSFRNVGSFHEACSMKIAERVVSLLDPVWLRIGAYWYPRGGIPIDVFWQTGSPPDGVWIPAQDVPGYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST7_GORGO
Sequence: MAEAATGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYILRVPLKINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAMIDIFCSAEFRDWNCKSIFMRVEDELEIPPAPQSQHFQN
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAPP_ROSCS
Sequence: MSHTPHNRRHESERLSATIRFLGNLLGDVIREQAGEAAFQLVERLRTLGKELRNGAPDRADAELRMMAARMTVADIQIVIKAFNAYFLLVNLAEQMQRVWVLRDRERKYPDTPRPESIAAAIAELHACGIPATTIQEWLDTACIQPVFTAHPTEARRRTALEKVRRLATLLDERTGDLHGFVREENTMRIREEIVSLWQTDEVRVVKPTVIDEVKNGMFYFESGLFDLIPRLYRELEYALRTTYPTHEWRVPPLLRYGAWMGGDRDGNPNVTHTVTIQAVRMMRAAAIERHIAAVEELSHRLGQSVRQAPVSDELRESLAHDASLFPEVADMLARRNPYELYRQKCTYIREKLIRTLDYARTASLDWGRSDSPPKGAYFSRTDLLDDLHVMERSLLSNNAAIVANGALRDLIRQAEVFGLHTATLDIRQHSERHTAALAEVLAAAGVCADYTALNEIERIELLSREIENPRPLIPTRLDYSPDTVEVIATFRAVASILERLSPEAVETCIVSMTRGASDLLAPLLLAKEAGLFRPFRFSRLSMAPLFETGADLACCDEVLEACMRLPIYRNHLALRGFVQEVMIGYSDSNKDVGYAAANWAIYQAQRKLRDFGRRHGIQMRLFHGRGGAIGRGGGPANHAILAQPPGSIGNQIKITEQGEVIADRYGLPLLAHRHIEQVINAVLRAGLLQRDDPPDEWTQALERLAALSQRHYRALVYERSDFVPYFRNVTPIAEISRLNIGSRPASRRNTERIEDLRAIPWVFSWMQSRHTLPGWYGLGFALETFVYAGEQSDASGSAIDRLALLQEMYARWSFFRVMIDNAQMILGKADLHIASRYAELAPDQNAAAAIFAAIREEYQRASRMIRQVARIERLLDNAPVLQHSIQRRNPYIDPMSYLQIELLRRLRAAPDGPDHAAIEDAILLSISGLAAGLMNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: KTHY_NITMU
Sequence: MRGKFITLEGIDGAGKTTHLRWLEYFLKERGKNVMVTREPGGTPLGEALRDILLDSRQTMHAETEALLMFAARREHLDKVILPALSRGEWVISDRFTDASFAYQGGGRGLSLQKLNELECWVQGEFQPDVTLYLDVSIASGRQRTSNIRQADRFEKEQDEFFRRVREAYLERAKEFPERIRVIDANQSLEDVRRSVEKSIATIYA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PSA_THEGJ
Sequence: MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKWKGGVVLAVEKRITSRLIEPSSYEKIFQIDDHIAAAPSGIIADARVLVDRARLEAQIYRLTYGEPVPLTVLVKKICDLKQAHTQYGGVRPFGAALLMAGVNEKPELYETDPSGAYFEWKAVAIGSGRNTAMAIFEEHYSDDIDMEGAIKLAILALAKTLEEPSPESIEVAYITLDEKRWKKLDKEEVAKYLNEILEEIKEEEVEEREEDYSELDQNY
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT_HYPJE
Sequence: MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIDGRSRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIMFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTTVVPIYEGFALPHAIRRVDMAGRDLTDYLMKILAERGYTFSTTAEREIVRDIKEKLCYVAHDFEQEIQTAAQSSSLEKSYELPDAQVITIGDRFRAPQALFHASVLGLESAGIDVTTFNSIMKCDVDVRKELYGNIVMSGGTTMFPQGISDRMQKEITASAPSSAMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: BUB33_ARATH
Sequence: MSGDRLEFENPIEDAVSRLRFSPQSNNLLVASWDSYLRLYDVESSSLSLELNSQAALLDCCFENESTSFTSGSDGFIRRYDLNAGTVDTIGRHDDISTSIVYSYEKGEVISTGFDEKIKFWDTRQRESLVFSTDAGGAVGCVTVSGNNLVVCVDASMHIYDLRNLDEAFQSYASQVEVPIRCITSVPYSRGYAVGSVDGRVAVDFPNTSCSSEIKYSFRCHPKSRNGRLDGVCINAIEFSPCGSGTFVTGDNEGYVISWNAKSRRRLNELPRYSNSIASLAFDHTGELLAIASSHTYQDAKEKEEAPQVFIHRL
What is the function of this protein?
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments.  Promotes the formation of stable end-on bipolar attachments.  Necessary for kinetochore localization of BUB1.  The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20 (By similarity).
What are the official names of this protein?
Mitotic checkpoint protein BUB3.3, Protein BUDDING UNINHIBITED BY BENZYMIDAZOL 3.3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BUB3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cytoskeleton, spindle. Note=Accumulates onto both kinetochores and the spindle microtubules in cell arrested in metaphase. Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition. Associates with unattached kinetochores upon spindle assembly checkpoint (SAC) activation. Present in the phragmoplast midline during the final step of cell division (By similarity).
Protein: FADI_CITK8
Sequence: MSQALPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVELGKMVVGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARILVDVNKARTTGQKLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWAEGKLADEVMTTYAPPYKEPFSEDNNIRGNSTLADYAKLRPAFDRQHGTVTAANSTPLTDGAAAVILMTESRAKELGLAPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTLADLSLIDMHEAFAAQTLANIQLLGSERFARDVLGRAHATGEVDDSKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FG17_DANRE
Sequence: MYGINQRYLYISFHFFVVWCHAQGEKNHPSPNFKQYVREQGSLTDQLSRRQVRVYQLYSRTSGKHVQIRGHRVSATADDGNSYARLYVETDTFGSRVRIKGAESGRYLCMNRRGKLVGKPNGRGRDCIFTEIVLENNYTALENARHEGWFVAFTRKGRPIRASKTRQNQREVHFIKRLHKGPQPFPNAEQPKHFEFISFPSTRRAKRNRKHQTAS
What is the function of this protein?
Involved in dorsal-ventral embryonic patterning, by promoting expression of bone morphogenetic protein (BMP) antagonists such as chd.  Also involved in anterior-posterior neural patterning and in mesoderm induction.
What are the official names of this protein?
Fibroblast growth factor 17, FGF-17, Fibroblast growth factor 17b, FGF-17b.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYF2_GEKJA
Sequence: MAAVEENEAPSPVMAITGISEDPASIAAEDTAAQKREEHLRKFRELHLKRNEARKLNHQEVVEEDKRLKLPANWEAKKSRLEWELKVEEKKKECVAKGEDYERVKLLEISAEDAERFERKRKKRNPDLGFSDYAAAQMRQYQRLTRQIKPDLEKYAKLREESGEEFYPTSNSLLHGTHVPCKEGVDKMVEDLEKQIQKREKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor syf2.
What is the protein family that this protein belongs to?
Belongs to the SYF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIG_POLNS
Sequence: MAVQIENLGSLDRKMTLEFARADLAKAREARLAKVGKSMKMAGFRPGKVPKNLVEKQHGMQVDFELQFDKAAELFYELAQKEGVALAGQPRLEPKSEIDAEKVVFDAFFEVLPEVKIGDFSKAEVTKYTTDIGEAEIDRALDALRKQQVHYHPRGEAGPHGDGGSNTAAQNGDQVVINFVGKIDGVEFAGGKAENFECVLGEGRMLPEFEAATLGLKVGESKSFPLSFPADYHGKDVAGKTAEFTITVKSVNWAHLPVVDDAFALSLGVTEGGVTKMRAEVKENLDREVKRRVTTLLKSEVMDKLNSLCELDVPKSLVASEQERLVEGARQDLMQRGVPNAKDAPIPAEIFAEQATKRVRLGLILSELVKNQNLIATADQIKAEIDEQATTYEDPKEVIRWFYRNPGRLKDIENLVLEDNVIKYFTSQAKVNDKSVTFEELSKLN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL36_CAUSK
Sequence: MKVRSSLKSLKSRHRDCKLVRRKGVVYIINKTDPRFKAKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RTCA_ECO55
Sequence: MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGEYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGEFKVAHPSCHLLTNIAVVERFLPVRFGLIETDGVTRVSIE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECU_OCEIH
Sequence: MNYPNGQQKVTTNHVVQKQDNRMFSNRGMSLEDDINATNEFYLETNQAVIHKKPTPVQIVNVHYPKRSAAVITEAYFKQASTTDYNGIYKGKYIDFEAKETKNKTSFPLANIHEHQINHMQKVIDQQGICFMLIRFTAHDETYLLDAKALLTFWNLKQDGGKKSIPYDMIRNQSQLIPFHYQKRVDYLAAVDKLYF
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKT6_CANGA
Sequence: MKIYYIGVFRSPAEQSSDEKALELTEVKDLSQFGFFERNSVGQFMTFFAETVATRTTAGQRQSVEEGNYIGHVYARSEGICGVLITDKDYPVRPAYTLLNKVLDEYLVAHPADQWKSITATNDSLKMAELSTYISKYQDPAQADAIMKVQQELDETKIVLHKTIENVLQRGEKLDNLVDKSESLTASSKMFYKQAKKTNSCCIIM
What are the official names of this protein?
Synaptobrevin homolog YKT6.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: GRCA_ECOLU
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGFAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: KUP_ECOLI
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell (PubMed:2649491, PubMed:8226635, PubMed:10214935, PubMed:11682179, PubMed:28522840).  Likely operates as a K(+):H(+) symporter (PubMed:10214935, PubMed:11682179).  Kup is probably the major potassium uptake system upon hyper-osmotic stress at a low pH (PubMed:10214935).  Can also transport Cs(+) and Rb(+) (PubMed:2649491, PubMed:28522840).  In the absence of potassium, Kup-mediated Cs(+) uptake partially supports cell growth, however, at a much lower rate than with sufficient K(+) (PubMed:28522840).  This effect depends on the maintenance of basal levels of intracellular K(+) by other K(+) uptake transporters (PubMed:28522840).
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCH1L_ECO57
Sequence: MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTASQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDAHPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDTGPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHATERGGIRALSEWLNENTDLDVTFIDIPNPA
What is the function of this protein?
Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides.
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: GPMI_SHEB5
Sequence: MTTAKRPLALLILDGWGYRENTHNNAIFHANTPVLDRLNAQYPHSLISGSGLDVGLPDGQMGNSEVGHINLGSGRVVYQELTRISKAIADHEFEQNPALCDAVDSAIKAGGAVHIMGLLSAGGVHSHEEHIEAMCRMAVARGATKVYLHAFLDGRDTPPRSAKSSLSHFDDLFTTLGHGRIASIIGRYFAMDRDNRWDRVSQAYDLITQGKSKFQYDNAVTALEAAYERNENDEFVSSSAITDADGQVATLQDGDALIFMNFRADRARQITRSFINPDFDGFERAVVPKMHFVTLTEYAGDIKAPIAYPSENLVNTLGEVLQKQGRTQLRISETEKYAHVTFFFNGGKEEPFEGEDRILINSPKVATYDLQPEMSSAELTDKLVAAIESTKYDVIICNYPNGDMVGHTGNFDAAVKACEAVDACIGRVVDALAKVGGECIITADHGNAEQMTDETTGQAHTAHTSELVPFVFVGRNATIDEGGKLSDVAPTILTLIGEAIPAEMTGKPLIHIKE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: SEPT8_CALJA
Sequence: MAATDLERFSNAEAEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKKASGWSSIYSVTIP
What is the function of this protein?
Filament-forming cytoskeletal GTPase (By similarity).  May play a role in platelet secretion (By similarity).  Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity).
What are the official names of this protein?
Septin-8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Synapse. Cell projection, axon. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Presynapse. Note=Expressed in axons of immature neurons, localizes to synapses in mature neurons.
Protein: C93A3_SOYBN
Sequence: MAFQVLFICLISTIVFASILWRKQNKNKTLLPPSPMPLPIIGHLHLLSPTPHQDFHKLSLRYGPIIHLFLGSVPCVVASTAEAAKEFLKTHEPAFSNRPANTVAVETLTYGFQDFLFAPYGPYWKFMKKLCMSELLGGHMLDQFLPVRQXETKKFIKRVLQKGISGEAVDFGGEFITLSNNIVSRMIVSQTSTTEDENEVEEMRKLVKDAAELSGKFNISDFVSFLKRFDLQGFNKRLEKIRDCFDTVLDRIIKQREEERRNKNETVGKREFKDMLDVLFDISEDESSEIKLNKENIKAFILDILIAGTDTSAVTMEWAMAELINNPGVLEKARQEMDAVVGKSRIVEESDIANLPYLQGIVRETLRLHPAGPLLFRESSRRAVVCGYDIPAKTRLFVNVWAIGRDPNHWENPLEFRPERFVENGKSQLDVRGQHYHLLPFGSGRRACPGTSLALQVVHVNLAVLIQCFQWKVDCDNGKVNMEEKAGITLPRAHPIICVPIRRLNPFPVV
What are the official names of this protein?
Cytochrome P450 93A3, Cytochrome P450 CP5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MSHD_RHOOB
Sequence: MSASVQSWTDRLDGAQAADVSALLGRATAADGTAPVSEQGVHAVSGAGGDGVRHLVETDADRIVGYAQLQPGHGEHPAMAELAVDPEARGRGIGGRLVAEVLSAGGPDTRVWAHGNLPAAQAVAQRLGLTGARELLQLRRPLAGAELPELVVLEGISLRVYRGVEDDPEVLRVNAAAFAWHPEQGSWTEREMAERRAEAWFDPAGLFMAFATSDEKRLLGFHWTKVHPKQGDEPAIGEVYVVAIGPDAQGRGLGRLLTLAGLHYLRDRGLGAVLLYVEGDNASALHTYDRLGFERFHTDVAYARA
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: EF2_SULTO
Sequence: MPRYKTVEQVLSLMKDITRVRNIGIIAHVDHGKTTTSDTLLAAAGIISQKVAGEALALDYLSVEQQRGITVKAANISLYHEIEGKGYVINLIDTPGHVDFSGRVTRSLRILDGSIVVVDAVEGIMTQTETVLRQSLEERVRPILFINKVDRLVKELKLSPQEIQKKLIDMIVEINNLIEMYAEPEYKDAWKIKPELGNVVFGSAKDKWGFSVPIAQKKGVKFSDVVNAYSSGDKSKVEELANRVPIHEALLETVIKFVPNPRDAQKYRIPKIWKGDLDSDIAKAMINADPNGPIVLMISDMKVDPHAGLVATGRVFSGTLRAGEEIWLVNAKRQQRVLQVSLYMGPTRELAEEIPAGNIAAALGLDQARSGETAVDIKYKDANVGSFESLHYVSEPVVTISVEPKNPKDLNKMIDALRKLSIEDPNLLVKINEETGEYLLSGMGFLHLEVSLQLLKENYGVDVVTSPPIVVYRESIRTKSQVFEGKSPNKHNKLYISVEPLNEQTIELIANGTIKEDMDSKEMARILKEQADWDYDEAKKIVAIDENINVFVNATSGVQHLREVMDTILQGFRLAMKEGPLAHEPIRGLKVVLHDAIIHEDPAHRGPAQLYPAVRNAIFAGFLTSKPTLLEPLQKLDIRVPMDFVGNVSGVITRKRGKILNMTQMGSIARITAEIPVSESFELASELRAASAGRAFWGTEFSRWAPVPDSLLLDVIMKIRERKGLPKELPKVEDFLA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDUW_CITRI
Sequence: MSHKIMAINAGSSSLKFQLLDMPQGKLLCQGLIERIGMANAGITLKAQEQKWQQTAPVADHREAVTLLLDMLTGHGIIRSIAEIEGVGHRVAHGGETFKDSARVTDETLAEIERLAELAPLHNPVNLLGINVFRQLLPDVPAVAVFDTAFHQTLNEAAYIYPLPWRYYEEFGIRRYGFHGTSHKYVSATLAEKLGVPLSALRVVSCHLGNGSSLCAIKGGKSVNTSMGFTPQSGVMMGTRSGDIDPSILPWLAQREGKTPQQLNQLLNNESGLLGVSGVSHDYRDVEQAADAGNPRAALALTLFAERIRATIGSYIMQMGGLDALVFTGGIGENSARARAAICQNLQFLGLSVDEAKNQRNATFIQADHALVKVAVINTNEELMIARDVMRIALAETPVAASA
What is the function of this protein?
Works with phosphate acetyltransferase (pta) to capture exogenous propionate and regenerate propionyl-CoA during degradation of 1,2-propanediol (1,2-PD).
What are the official names of this protein?
Propionate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family. PduW subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_CLOTE
Sequence: MKKEDKDWIELTIITSSQAVEAVSAILYNTDVQGIAIEDSKDVEFQKKNKGDWDYFDETLINIEEGAVIKAYYREDKNFMKYLKYIEESVKNLEQLGFDKGKGIVTTSKVNEEDWENNWKKYYKPTKVGEKIVIKPIWEEYGENPEEIILELDPGMAFGTGTHETTRMCIESLEKYVKEEDVVFDIGTGSGILGIAAAKLNAKKVIGVDLDEVAVDSAKKNVGFNHLDNIEILHGDLMEVVKGKCNIIVANIIADIIILLSKDVKKFLEDGGYFISSGIIKDRKEEVVDSLKENGFKIEEIKEQGEWVCVVASL
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEP1_YEAST
Sequence: MESRTTGPLTTETYDGPTVAFMILGAALVFFMVPGLGFLYSGLARRKSALALIWVVLMATLVGILQWYFWGYSLAFSKSAPNNKFIGNLDSFGFRNVYGKKFDEDAYPELAYATFQMMFSCVNLSIIAGATAERGRLLPHMVFLFILATIGYCPVTYWIWSPGGWAYQWGVLDWAGGGNIEILSAVSGFVYSWFLGKRNEKLLINFRPHNVSLVTLGTSILWFGWLLFNSASSLSPNLRSVYAFMNTCLSAITGGMTWCLLDYRSEKKWSTVGLCSGIISGLVAATPSSGCITLYGSLIQGIVAGVVCNFATKLKYYAKVDDAMDILAEHGVAGVIGLIFNALFGADWVIGMDGTTEHEGGWVTHNYKQMYKQIAYIAASIGYTAAVTAIICFVLGYIPGMRLRISEEAEEAGMDEDQIGEFAYDYVEVRRDYYLWGVDEDSQRSDVNHRVNNAHLAAERSSSGTNSSSDGNGEMIQSEKILPIHQEDPANR
What is the function of this protein?
Transporter for ammonium (both charged and uncharged NH3 and NH4) to use as a nitrogen source.  Can also transport methylamine.  The affinity of MEP1 is about twenty times lower than that of MEP2.  MEP3 has the lowest affinity.
What are the official names of this protein?
Ammonium transporter MEP1.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 3S1D_LATCO
Sequence: MKTLLLTLVVVTMVCLDLGYTRRCFNQQSSQPKTTKSCPPGENSCYNKQWRDHRGSITERGCGCPKVKPGIKLRCCESEDCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin D.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.