PharMolix/UniProtQA huggingface dataset:
Protein: RPPH_YERPA
Sequence: MIDDDGYRPNVGIVICNRQGEVLWARRYGQHSWQFPQGGINPGETPEQAMYRELFEEVGLNKKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQRWFLLQLMCNEAEINMQRSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAATVMPVQEVAPPRVPPAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: LPOA_SHIF2
Sequence: MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDSQRREKTLLAAEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIAQEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDPDMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTIQQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTADSVASPAQASVSDLTGDQPAAQPVPVSAPATSTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNVEELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIPRSALGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITPRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATLYASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMGVDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRKLSWLQYQQGQVVPAS
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: PFBA_STRR6
Sequence: MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQGILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNSISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK
What is the function of this protein?
Acts as a fibronectin-dependent adhesin and invasin.  Binds host (in this case human) fibronectin, plasmin, plasminogen, and human serum albumin.  Where the bacteria adhere to human cells there is major recruitment of microvilli which seem to fuse to cover the streptococcal chains.  Antibodies to this protein reduce bacterial growth in human blood.
What are the official names of this protein?
Plasmin and fibronectin-binding protein A.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: SYL_DESAH
Sequence: MEERYNPEKVEPLWQAYWNQHQTFKATEDGSKPKYYLLEMFPYPSGKIHMGHVRNYTIGDVVVRYKRMKGFNVLHPMGWDAFGMPAENAAIDNNTHPAAWTYENIRTMRRQLKRMGFSYDWDREIATCRPEYYRWEQWLFLKMLDKDMVYRKESYVNWCDHCQTVLANEQVEQDMCWRCGKPVQQKKLWQWFFRITDFAEDLLVHCDKLPGWPDNVTLMQKNWIGKSQGSEIRFPIQGIDENIPVFTTRPDTLFGSTFMCLAPEHPLVETLSRGTDQAAAVTEFTTRVLNQERSSIALEKYEKEGVFTGAWCINPVTREKMPIYTANFALMEYGTGAVMSVPAHDQRDFDFARKYGLPIKVVIQPPGEPLDPATMIEAYTGQGTLADSGEFSGLGNLEAMGAITRWLENKGLGKTTVSFRLRDWGISRQRYWGTPIPVIHCPDCGIVPVKEETLPVVLPEDAALLDNGGSPLATLDGFARVNCPVCNRADARRETDTMDTFVESSWYFARYCSPRYDKGMFDPAAVAYWMPVDQYIGGVEHAILHLLYSRYFMRVLNTLGLIDFKEPFERLLTQGMVCKETLTCPEHGFIYPDDAETVNDKVICKRCNSDVEVGRVIKMSKSKKNVIDPNALLDQYGADITRLFCLFAAPPEKDLEWNDDGVEGCNRFINRVWRLADRCKSTYIDLLPYSGVVADLKGEPKKLFIKANQTIKKVTDDIEESFHFNTAISAVMELVNAMYSADLDPDQTDMGEVALFCIENIVLLLSPIVPHFCEELWSILGHGPSIVDQPWPDYQKDALLTDEILIVVQVNGKLRSKFSVDAAVSDDFIRKAALADEQVEKYIKGKTIKKVIVVKKKLVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAI7_HUMAN
Sequence: MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVENSSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPPETTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLVTFSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIKLKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMALLSSAFAFGWSKWNLLCNSTKVVFKVREHLTEACTENPNWALLMFSGDRAQRLKIKEESEAFSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS
What is the function of this protein?
Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function.  May also act as a cell cycle regulator.
What are the official names of this protein?
Dynein axonemal intermediate chain 7, Cancer susceptibility candidate gene 1 protein, Protein CASC1, Cilia and flagella associated protein 94, Lung adenoma susceptibility 1-like protein, Protein phosphatase 1 regulatory subunit 54.
What is the protein family that this protein belongs to?
Belongs to the DNAI7 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm. Note=Colocalizes with microtubules in interphase.
Protein: RL13_CANAL
Sequence: MAISKNLPLLNNHFRKHWQERVRVHFDQAGKKASRRQSRLRKAAKIAPRPIDALRPVVRAPTVKYNRKVRAGRGFTLAELKAVGIAPKYARTIGISVDHRRQNKSQETFDANVARLQEYKSKLVIFDKKTKASEVASFEQVDVSATFPVEQPAPESGLRAVEVPEQTAYRTLRLARNEKKYKGIREKRAKEKAEAEAEKAKK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
Protein: UPP_STAAN
Sequence: MSKVHVFDHPLIQHKLSYIRDVNTGTKEFRELVDEVGMLMAYEVTRDLELQDVDIETPVTKMTAKRLAGKKLAIVPILRAGLGMTDGILSLVPAARVGHIGLYRDPETLKAVEYFAKLPQDITERQIIVVDPMLATGASAIEAITSLKKRGAKNIRFMCLIAAPEGVEKMHEAHPDVDIYIAALDEKLNDKAYITPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: VL1_HPV61
Sequence: MALWRPGDGKVYLPPTPVSKVISTDRYVQRTNLFYYGGSSRLLTVGHPYCSLQLDGLQGKKNTIPKVSGYQYRVFRVQLPDPNKFALPDGTLYNPDTERMVWACRGIEVGRGQPLGVGTSGHPLYNRLDDTENTTLLVAESSDSRDNVSVDYKQTQLLIVGCKPPIGEHWTKGTACANPAPRPTDCPPLEFTNTTIQDGDMVETGYGAIDFAALQENKSEVPLDICTTICKYPDYLQMAAEPYGDCMFFCLRREQMFARHFFNRQGVMGEALPDSYYLKGANDKAAPGSYIYSPTPSGSMVSSDSQLFNKPYWLQRAQGHNNGICWFNELFVTVVDTTRSTNLTICTATSPPVSEYKATSFREYLRHTEEFDLQFIFQLCKIHLTPEIMAYLHNMNKALLDDWNFGVVPPPSTSLEDTYRFLQSRAITCQKGAAAPPPKEDRYAKLSFWTVDLRDKFSTDLDQFPLGRKFLLQAGPRSVSVSRKRAAPSSTPTSSPATKRKKRKQ
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ASTE_VIBPA
Sequence: MTKSLFRQSFLTDTLDVHIDVAPAEQVLSNGVQLKLYQRGVLEVIPENPTQETKNIIISCGIHGDETAPMELVDSIIKDIESGFQKVDARCLFIIAHPESTLAHTRFLEENLNRLFDEKEHEPTKELAIADTLKLLVRDFYQDTEPKTRWHLDLHCAIRGSKHYTFAVSPKTRHPVRSKALVDFLDSAHIEAVLLSNSPSSTFSWYSAENYSAQALTMELGRVARIGENALDRLTAFDLALRNLIAEAQPEHLSKPCIKYRVSRTIVRLHDDFDFMFDDNVENFTSFVHGEVFGHDGDKPLMAKNDNEAIVFPNRHVAIGQRAALMVCEVKTRFEEGELVYD
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: HPAB1_PSEU2
Sequence: MSGINGAGPSNFFWRWRADDEPVTERERDSSSGANLTNSPQLRPESPTVSGRRLLRSNALSRQTREWQETTSASAERATPPVEPRQPPEAQPAERIVAERIVQELVRAGANLNNVRTMLRNVMDNNAVAFSRVEWNILLQHFPDMHTNGISSDSVLANELRQTLRQVVHQQRTQRALAPILSPAPSRPVASSSRSSQRTLLGRFTGWMAPRQTSSSSQATSSTSVDRHPQDLNQLESLRLADAERRNRSANQTDTDEALRRLTQAGVDMERLSTSLGRYIHSFQPAPPDLRRLLESVGIDPDIPEELTLVNNPVLNLNVALNRMLASRQATTESSSVFPSRAGDTRVRTLPVMPEREDNENNVAYGVRLLRLNPEAEVERVVEAFITDPSSRPEVVADIHAVLRSITSQFRQLRTISKADAESQDFRDAADYPDDPTSCLFGEDLSLSNPHQQVIGLAGESTDILQPYSQEGNKALRFMDMKKLAEHLASKPVHPMNRDRLDDKNIAGYAFRVVPD
What is the function of this protein?
Effector protein that plays different roles depending on the species and plant cultivars that interact with the pathogen.  Acts as a virulence determinant by enhancing the development of disease symptoms and bacterial growth.  Acts as an avirulence factor by eliciting hypersensitive response (HR) and plant resistance (By similarity).
What are the official names of this protein?
Effector protein hopAB1.
What is the protein family that this protein belongs to?
Belongs to the HopAB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (TTSS).
Protein: TP1A_LITCL
Sequence: FLPFLAKILTGVL
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus.
What are the official names of this protein?
Temporin-1Ca.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCA_PSEAB
Sequence: MQIYKVGGAVRDRLLGRPVTDIDWVVVGASSDEMLARGYRPVGADFPVFLHPQSGEEYALARTERKSGRGYGGFTFHASPEVTLEEDLTRRDLTINAMAEDEQGRVIDPYGGQADLEARLLRHVSPAFAEDPLRVLRVARFAARYAGLGFRIAAETLALMRQLAESGELQALTPERSWKEISRALMEPNPEVFIQVLHDCGALAELIPEVEALFGVPQPAAHHPEIDTGVHVLSVLQQCARHRQPLSVRWACLLHDLGKGLTSEADWPRHIAHEARGVPLIDAVNQRFRVPRDCQELARLVGEYHTHAHRALELRPNTLLELLQSFDVYRRPQRFEEFVAASEMDARGRLGLEQRDYPQAAYLLGAAQAARAVSVKPLVEKGLKGAELGEALKRARLAALKAYKEERGKA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: TNFA_LAMGL
Sequence: MSTESMIRDVELAEEALPKKAGGPQGSRRCLCLSLFSFLLVAGATTLFCLLHFGVIGPQKEELLTGLQIMNPLAQTLRSSSQASRDKPVAHVVADPAAQGQLQWEKRFANTLLANGVKLEDNQLVVPTDGLYLIYSQVLFSGQRCPSTPVFLTHTISRLAVSYPNKANLLSAIKSPCQGGTSEEAEAKPWYEPIYLGGVFQLEKDDRLSAEINMPNYLDFAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: TLE5_RAT
Sequence: MMFPQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQQLQAHQLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSLSALGSQTHLSKEDKNGHDGDTHQEDDGEKSD
What is the function of this protein?
Transcriptional corepressor.  Acts as dominant repressor towards other family members.  Inhibits NF-kappa-B-regulated gene expression.  May be required for the initiation and maintenance of the differentiated state.  Essential for the transcriptional repressor activity of SIX3 during retina and lens development (By similarity).
What are the official names of this protein?
TLE family member 5, Amino-terminal enhancer of split, Amino enhancer of split, Grg-5, Groucho-related protein 5, Protein ESP1, R-esp1, Protein GRG.
What is the protein family that this protein belongs to?
Belongs to the WD repeat Groucho/TLE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WOX11_ORYSI
Sequence: MDGGHSPDRHAAAAAGEPVRSRWTPKPEQILILESIFNSGMVNPPKDETVRIRKLLERFGAVGDANVFYWFQNRRSRSRRRQRQLQAQAQAAAAAASSGSPPTASSGGLAPGHAGSPASSLGMFAHGAAGYSSSSSSSWPSSPPSVGMMMGDVDYGGGGDDLFAISRQMGYMDGGGGSSSSAAAGQHQQQQLYYSCQPATMTVFINGVATEVPRGPIDLRSMFGQDVMLVHSTGALLPANEYGILLHSLQMGESYFLVTRSS
What is the function of this protein?
Transcription factor which may be involved in developmental processes.  Promotes the development of crown roots (both initiation and elongation), main components of the fibrous root system, by regulating the expression of genes required for crown root development and hormone-responsive genes involved in cytokinin (e. g.  RR1, RR2, RR3 and RR4) and auxin (e. g.  IAA5, IAA11, IAA23 and IAA31) signaling.
What are the official names of this protein?
WUSCHEL-related homeobox 11, OsWOX11.
What is the protein family that this protein belongs to?
Belongs to the WUS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPLA_YERPP
Sequence: MSSLRLLISDSYDPWFNLAVEECIFRQMSPNQRVLFLWRNADTVVIGRAQNPWKECNTRRMEQDGVKLARRSSGGGAVFHDLGNTCFTFMAGKPGYDKTISTQIILNALASLGIQATASGRNDLVVINGEDERKVSGSAYKETKDRGFHHGTLLLNADLSRLADYLNPDPKKLQAKGITSVRSRVTNLVELLPGIDHGKIRTAIEQAFFAYYDEQVSAEVISPQSLPNLPGFTEQFAKQSSWEWNFGQAPAFSHVVDTRFIWGGIELHFDVLHGAIDRCQIFTDSLNPTPLEALAQRLQGAAYRPDAIDKICQHWIDDFPELQTELQQACHWLVEVLR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y13B_BPT4
Sequence: MKLTTEQKVAIREILKTKLSMGVSNVVFEKSDGTIRTMKGTRDADFMPTMQTGKLTESTRKESTDMIPVFDVELGAWRGFSIDKLISVNGMKVEHLLQFIGK
What are the official names of this protein?
Uncharacterized 11.5 kDa protein in Gp31-cd intergenic region, ORF B.
Protein: Y083_ARCFU
Sequence: MRAMSSQRIEGEKIRCVGRRISKPRLIHQTGKHRAIEIFVEGRPAKAEVVRAWRVLKTAED
What are the official names of this protein?
Uncharacterized protein AF_0083.
Protein: SYA_ANADF
Sequence: MKTAAQIRELFLRFFEEKAHRRVPSSSLVPQNDPTLLFTNAGMNQFKDVFTGREKRDYSRATTAQKCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGDYFKKEAIAWAWELVTSERWLAISKERLAATVFAGEGTLPWDEEAYRLWEAQGVPPERIHKLGAKDNFWAMGDTGPCGPCSELHFFQGNDIPCAEEKAGRTCQGVACDCDRWLEIWNLVFMQFERGADGGLTPLPKPSIDTGAGLERMAAVVQGKRSNYDIDAFQSIIRAIEKLAGKRYGATDADDDVSMRVIADHARATTFLVGDGVLPANEGRGYVLRRIMRRAIRHGKRLGLERPFLADVCEAVMEEMGGAYPETRENRAFIVKVAGQEEESFRRTLDKGLAILETEMRKAIPPETHLGKPATPPPSAPRPVIDGKLAFQLYDTFGFPLDLTRVIAAERGFDVDEQGFDRNMAEQRARSEWKGSGEQAVGDLHKQIASELGETRFLGYEAPTARAEVKALLANGARAAKAARGDKVEVVTAATPFYGESGGQVGDQGSIAAPGGRVRVEDTRRPVPGLVTHVGVVEEGELAVGDLVELAVDDRRRDLIRANHSATHLLQLALRETLGDHVKQAGSIVAPDYLRFDFSHFQPLSEEELNAIERRVNELVRENAETETAVLKLEDARQSGAMMIFGEKYGDVVRVVRLGPSKELCGGTHVRRTGDIAFFKIGSEESIAAGVRRIVAYTGPQAIELSQREADELRRAAALFKAGAFEVAQKIEQTQKRVKDLERALDEAKGKIASAQSGDLAAQARDVKGAKVLAVRVQGDGKSLRELADKLRDRLGTGVVALGAEQDGKAILLVAVTKDLTARLKAGELVKEAAKLVGGSGGGKPDLAQAGGSDPAGLEKALAKVQELAVAALG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_ECO24
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAYILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: EF1A1_CANAL
Sequence: MGKEKTHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYHVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGTGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMDSVKWDKNRFEEIIKETSNFVKKVGYNPKTVPFVPISGWNGDNMIEPSTNCPWYKGWEKETKSGKVTGKTLLEAIDAIEPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGIIKAGMVVTFAPAGVTTEVKSVEMHHEQLAEGVPGDNVGFNVKNVSVKEIRRGNVCGDSKNDPPKGCDSFNAQVIVLNHPGQISAGYSPVLDCHTAHIACKFDTLVEKIDRRTGKKLEENPKFVKSGDAAIVKMVPTKPMCVEAFTDYPPLGRFAVRDMRQTVAVGVIKSVEKSDKAGKVTKAAQKAAKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 1, EF-1-alpha 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC186_HUMAN
Sequence: MSETDHIASTSSDKNVGKTPELKEDSCNLFSGNESSKLENESKLLSLNTDKTLCQPNEHNNRIEAQENYIPDHGGGEDSCAKTDTGSENSEQIANFPSGNFAKHISKTNETEQKVTQILVELRSSTFPESANEKTYSESPYDTDCTKKFISKIKSVSASEDLLEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKKLIKENKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARSSAEDRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADNGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKT
What are the official names of this protein?
Coiled-coil domain-containing protein 186, CTCL tumor antigen HD-CL-01/L14-2.
Protein: OPN4_PHOSU
Sequence: MDSPPGPTAPPGLTQGPSFMASTTLHSHWNSTQKVSTRAQLLAVSPTASGPEAAAWVPFPTVDVPDHAHYILGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCEFYAFCGAVLGITSMITLTAIALDRYLVITRPLATIGMGSKRRTALVLLGIWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPQVRAYTMLLFCFVFFLPLLVIIFCYISIFRAIRETGRACEGWSESPQRRRQWHRLQSEWKMAKVALIVILLFVLSWAPYSTVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIVYAITHPKYRAAIAQHLPCLGVLLGVSSQRNRPSLSYRSTHRSTLSSQSSDLSWISAPKRQESLGSESEVGWTDTEATAVWGAAQPASGQSSCGQNLEDGMVKAPSSPQAKGQLPSLDLGMQDAP
What is the function of this protein?
Photoreceptor that binds cis-retinaldehydes (By similarity).  Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light (By similarity).  May be involved in the optokinetic visual tracking response (By similarity).  May be involved in the regulation of retinal hyaloid vessel growth and regression (By similarity).
What are the official names of this protein?
Melanopsin, Opsin-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendrite. Perikaryon.