PharMolix/UniProtQA huggingface dataset:
Protein: SODM_MYCIA
Sequence: MAEYTLPDLDWDYAALEPHISGQINEIHHSKHHATYVKGVNDALSKLEEARANEDHAAIFLNEKNLAFHLGGHVNHSIWWKNLSPDGGDKPTGELAAAIDDAFGSFDRFRAQFSAAANGLQGSGWAVLGYDTLGNRLLTFQLYDQQANVPLGIIPLLQVDMWEHAFYLQYKNVKADYVKAFWNVVNWADVQKRYAAATSKTQGLIFG
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: Y1931_MYCTU
Sequence: MVIVGFPGDPVDTVILPGGAGVDAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLGRTPSDDALGLCRTFRPRISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA
What is the function of this protein?
Controls the expression of genes important for virulence.
What are the official names of this protein?
HTH-type transcriptional regulator Rv1931c.
Protein: KCY_METVS
Sequence: MIITIGGLPGTGTTTISKLLSEKYGLSHVCAGFIFRDMAKENNMTLQEFSNYAEKNSGVDNEIDRRQVEAAKSGNLILEGRLAGWILKKNDMVPDLSIWLKADPMVRCKRISEREHENVDLALEKMLLREASEKKRYKEIYNIEIDDLSIYDLVIESSKWGATGVFNIIEKAIK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_STRPQ
Sequence: MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVRSEQAARDFQIYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSVMDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVDMFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDILDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAITQEITEIVAGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSA2_NEUCR
Sequence: MADRYSFSLTTFSPSGKLVQIEYALNAVNQGVTALGIKATNGIVLATEKKSSSPLADPSSLSKISLITPNIGMVYSGMGPDYRVLVDRARKVSHTGYKRIYNEYPPTRILVQDVARVMQEATQSGGVRPYGVSLLIAGWDEGGPMLYQVDPSGSYFPWKATAIGKNATTAKTFLEKRYTEGLELEDAVHIALLTLKETIEGEMNGDTIEIGIVGPPADHLLGVEGVEGAKGPRFRKLSPQEIEDYLTNL
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit alpha type-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MENB_ARATH
Sequence: MADSNELGSASRRLSVVTNHLIPIGFSPARADSVELCSASSMDDRFHKVHGEVPTHEVVWKKTDFFGEGDNKEFVDIIYEKALDEGIAKITINRPERRNAFRPQTVKELMRAFNDARDDSSVGVIILTGKGTKAFCSGGDQALRTQDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEAEKMGLINTVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQGLGGDATLLFYGTEEATEGRTAYMHRRPPDFSKFHRRP
What is the function of this protein?
Involved in the biosynthesis of phylloquinone (vitamin K1).  Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) (By similarity).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal, DHNS, Enoyl-CoA hydratase/isomerase D, ECHID, Naphthoate synthase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
What are the subcellular locations of this protein?
Peroxisome.
Protein: DSRB_SALPA
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNESGHQDGIFVEKAEQD
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: SYDND_COREF
Sequence: MLRTHLSGELRKENAGQSVTLTGWVARRRDHGGVIFIDLRDRSGIAQVVFRNEDVAERAHALRSEFVLQVTGVVEKRPEGSENPNLASGDVEVSVTDFTVLNESAPLPFQIEDASSAGEVGEETRLKYRYLDLRRPVQANALRLRSAANKAARTVLDSHDFTEIETPTLTRSTPEGARDFLVPARLKPGTFYALPQSPQLFKQLLQVAGMERYYQIARCYRDEDFRADRQPEFTQLDVEMSFVDQEDVIALAEEILTEVWKLIGYEISTPIPRITYADAMRLYGSDKPDLRFDIQITECTDFFADTTFRVFKNEYVGAVVMKGGASQPRRQLDAWQEWAKQRGAKGLAYILVGEDGELGGPVAKNITDAEREGIAAHVGAEPGDCIFFAAGDTRSSRALLGAARDEIARKLDLIRDGEWSFVWVVDAPMFESAADATASGDVALGNSKWTAVHHAFTSPKPEFLDTFDENPGEALAYAYDIVCNGNEIGGGSIRIHQRDVQERVFKVMGISEEEARDKFGFLLDAFAFGAPPHGGIAFGWDRIVSLLGGFDSIRDVIAFPKSGGGVDPLTDAPAPITPLQRKESGIDAKPKAAENKPEEK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_BORRA
Sequence: MFCFLGLRLLKYITFRTAYATIFAFLLALIFGPFIISRLKKLKLDQILRKDGPKHHLSEKMGIPTMGGVLIFFCVLVSLFFWIHFFNIYFLIVLFVMVSFACLGFTDDLLKIKRKNSDGLNPKFKIYGQILFSFISVVMLYYFGGEHVSILYFPFFKSLKLDLGILYIPFGMFVLISASNSFNLTDGLDGLAIGLSIVVIGALIIIAYLTSRVDFALYLNIPNVKGCEELVIFLGALLGGSFGFLWFNAYPAKIMMGDTGSLSIGAVLGMVALILKSEILFAILAGVFVVETLSVIIQVVVYKKTKKRVFKMAPLHHHFEELGWSEMQVVIRFWIIGLIFAILALSTIKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDK1_ENCCU
Sequence: MTESFQKLEKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLKHSTIVELSDVIYNNNKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLTAMEYCHSRNIFHRDLKPQNILVDPKENIKLADFGLGRAAGIPLRTYTTEVVTLWYRPPELLLGCKYYDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNVENFPNYKVEFPVWDPVDLKTIFRGDPDFVDLISKMLEYDPKMRMTAKNGLSHKYFEGMPLIME
What is the function of this protein?
Cyclin-dependent kinase that acts as a master regulator of the mitotic and meiotic cell cycles.
What are the official names of this protein?
Cyclin-dependent kinase 1, CDK1, Cell division control protein 28 homolog, Cell division protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUC_SHEPA
Sequence: MAKTLYEKVWDSHVVVAPEGEAPIIYVDRHLVHEVTSPQAFSGVKVAGRQLRAPQKTFATMDHNTSTTSASLDALSPMARTQVETLEQNCKEFGVRLYDIHHKNQGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVMATQTLRQLKAKTMKIEVRGHVASGITAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMIAPDATTAEYLEGREFSPKGESWSQAVAAWEQLKTDEGAVFDASVVLDAIDIAPQLTWGTNPGQVVAIDQLVPNPLDATNSTVRSSIEKALEYVDLTAGTLMTDVSINKVFIGSCTNSRIEDLRAAAVHAKGRKVADGVKAIVVPGSGLVKEQAEAEGLDKIFTDAGFEWRLPGCSMCLAMNDDKLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAVAGHFVDIRKPY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: AROB_BACCR
Sequence: MGNIHIQTKSKEYDVHVGKEVLSNLTTIVQNMQPAVSNVMIISDEAVASLHLQTVIDALQVEQHVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLILALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVELYHWLKEEVQTLADLHDEKLIHILTKAIPVKANVVSQDETEKGVRAHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVDLAYEDMKQWFLKYGYPKMPGDLNVERIVQLMKQDKKANAGAIHMVLMQEYGVVNVVSISDETVHIALEAFQKDMV
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTR5A_MOUSE
Sequence: MELAHSLLLNEEASNQLGAVQKAEFIFEWLRYLEKLLLATNREDVREKQKTLVGQLLSLLNSSPGPPTRKLLAQDLAILYSVGDTVSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILANGFTDTVVNILKAMKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAIFMWSTDVDSVATLCFKSFEGSNYDVRISVSKLLGTVLAKAVTAKHPGAGSKQSARRVSLEEVLELLGAGFLRGSSGFLRASGDMLKGNSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNLAAFLSHILSLVSQSNPKATQTQIDAVCCRRCVSFILRATLGGLLGEKAQIAAAKEICQAVWRLKKVMDAALSDGNVETRLSSTDVAASQHVLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLAILKSSPEAVTGFSSAVAALLGSVTHCPLGIPHGKGKIIMTIAEDLLCSAAQNSRLSLQRTQAGWLLVAALMTLGPAVVSHHLTRVLLLWKCVFPASPRDLETEKSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQRLLPPLPCAVDLLTQLSSILKTYGSSLKTPSIVYRQRLYELLILLPPETYKGNLCVILKELAAELTAPDTQAAASTCLLPALCHPDDLLILSPLLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCATVDEAQRVLILEQLLNSIKHTKGARQQTVQLHVVSAISNLLKYVAGSKQSLGPEVRRLVLTLVLGALESPTPLLRCAASEAWARLAQVADDGAFTAGLAQLSFDKLKSARDVVTRTGHSLALGSLHRYLGGIGPQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLTIDSAGALYHVHVESTLSLIVMLLLNVPPTHAQVHQSLGRCLNALITTLGPELQGSNTSVSALRTSCLLGCAVMQDHPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAIMLARDGRDAAADANLREVGLEGALLALLDRETDESLCQDIRETLHHMLTSMAVGKLTLWLKLCKDVLAASADFTAVTCVDTMQEEEGDRGDDASVLTRGDDKPHPFSNPRWATRVFAADCVCRIINQCENANRAHFDIALAQEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLDTLLVVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLSDLRRVHQLLVSSLTKIQAGKEALSQLYNESASTMEILAVLRAWAEVYIIAVQRHKNHKQALKTTVNSEDSMRNGSSSAAGLLDLVCTDLATLSKLWLAALQDFALLTLPAEFASQLPTEGGAFYTAETSKSAKLHYHDSWALILHAAALWLTSTGFADPDEGGANLSRPVTPTSMCQGSSSSGAAVKSPEDVYTDRFHLILGISVEFLCSLRSDASLESIMACLRALQALLDVPWPRWRIGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLAGSPGGKASKPKTLLEEGSRLVAAALAILAELPAVCSPEGSISILPTVLYLTIGVLRETAVKLPGGQLSCTVTASLQTLKGILTSPMARAEKSHEAWTSLLQSALATVLDCWSPVDGAQEPDEVSLLTAVTVFILSTSPEVTTVPCLQNRCIEKFKAALESKDSVVQMKTCQLLHSIFQYPKPAVSYPYIYSLASSIVEKLQDIARRKPEDATELQLCQEGIKLLEALVAIAEEEHRAQLVACLLPILISFLLDENALGSATSVTRSLHDFALHSLMQIGPRYSSVFKRVMASSPALKARLEAAVKGNQESVRVDPPSKHAKNLARNSSIQLKTNFL
What are the official names of this protein?
HEAT repeat-containing protein 5A.
What is the protein family that this protein belongs to?
Belongs to the HEATR5 family.
Protein: UPP_THET8
Sequence: MRITLVDHPLVQHKLAHLRDKRTGPKDFRELAEEVAMLMAYEAMRDLELEETTVETPIAPARVKVLSGKKLALVAILRAGLVMVEGILKLVPHARVGHIGLYRDPESLNPVQYYIKLPPDIAERRAFLLDPMLATGGSASLALSLLKERGATGVKLMAILAAPEGLERIAKDHPDTEVVVAAIDERLNDHGYIVPGLGDAGDRIYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NUOI_HYDCU
Sequence: MIAFIKHQVKTFGLIELFKGLAVTGKYLFKKKITVRYPEEKTPLSPRFRGHHALRRYENGEERCIACKLCEAVCPANAITIESEERDDGTRRTTQYDIDMFKCIYCGFCEEACPVDAVVETRVFEYEFHERGTHIMTKEQLLAFGDKHESQIAADRAADAKYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL34_PYRCJ
Sequence: MPRPAYRSRSLRRVKVKTPGGRTVVHYEKRAKGVPKCAVTGQPLGGMNSKVYRFGISTRAPSRPYGGVVSHKVLARAIRYAVRR
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: RL29_BORPA
Sequence: MKASELRSKDAAELGKELESLLKAQFGLRMQKATQQLANTSQLRNVRRDIARVRTLLTEKAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PAN_SULIN
Sequence: MSGDFDTIRDASSSDEVQLVRLLEEKIKSLQIEIENLRKELNYYKAEMEKMLSPPLIEAVVLDVLPDGRVLVRSSSGPNLVVNVASHIDQKLIKPGVSVALNQRGSTILEVLPQKEDPIVKTMEIVEKPNVTYSEIGGLEEQIKELREVVELPLKKPEIFREIGVEPPKGVLLYGPPGTGKTMLAKAVATESNAVFIHVVASEFAQKFVGEGARIVRELFEMAKRKAPSIIFIDEIDAIGAKRIDIGTSGEREIQRTLMQLLAELDGFNPLDNVKIIAATNRIDILDPALLRPGRFDRIIEVPLPDFRGRTEIFNIYLKKMKVEDNINLELLSQLSEGFSGADIKNVCVEAAYMAIRDGRNKVTMKDLVNAITKINVKRNNMESMKERREKYS
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBEAG_HHBV
Sequence: MWSLRLHPSPFGAACQGIFTSTSLLFLVTVPLVCTIVYDSCLYMDVNASRALANVYDLPDDFFPQIDDLVRDAKDALEPYWKAETIKKHVLIATHFVDLIEDFWQTTQGMSQIADALRAVIPPTTVPVPEGFLITHSEAEEIPLNDLFSNQEERIVNFQPDYPITARIHTHLRVYTKLNEQALDKARRLLWWHYNCLLWGEATVTNYISRLRTWLSTPEKYRGKDAPTIEAITRPIQVAQGGRNQTKGTRKPRGLEPRRRKVKTTVVYGRRRSKSRGRRSSPSQRAGSPLPRNRGNQTRSPSPRE
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: CDC63_SULTO
Sequence: MSIRDTLKGGKGEVIKDPRVFIDPLTVFKDIPFREDILKEVAVAVRYFVKSDVKFSTLFLGLTGTGKTFVARYMLNEIEEVKQEDSDYSKVKQAYVNCREVGGTPQAVLSALTERLTTDEVPKHGINLGEYIEKIKEELNGKKALVYLDEVDTLIKRRGGDIVLYQLLRADADISVIMISNDINIRDYMEPRVLSSLGPTVFFKPYDAEQLKHILSIYAEYGLYRGTYDDNILSYIAAISAKEHGDARKAVNLLFRAAQLASGEGFIRKDHVDRAIIEYEQERLIEAIKALPFHYKLALMATMDAEDVVTAHKIYSDLCNQYKQKPLSYRRFSDIISELDMFGIIKVKIINKGRAGGIRKYIEITDKDKIRKALEDTMNLGFEEQW
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 3.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: ARGB_ALKMQ
Sequence: MNLSPNQKADVLIESLPYIKKFYNEIVVIKYGGSAMVNDELKESIIKDIVLMKYVGMHPVVVHGGGPEITNMLKVFDKESKFVDGLRVTDQATMEITEMVLLGKVCQEIVTRINQNGVRSIGICGKDGSMIKTVPKDPELGLVGGITSIDTDLIKTIIEKGYIPVISPIGCGPAGESHNINADEVAGKLAAALGAKKLMLITDVAGVLRDQHDEASLISDIKTNEIEEYIETGVIKGGMIPKISCCFDAVANGVERAHIIDGRKSHSMLLEIFTDQGVGTMITHGGDQNGNSKNNKQWKSIFNEHLWENAYSLPGR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAT_HUMAN
Sequence: MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANLAGLFPEAAPGSPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLALQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPGCLRALGGPV
What is the function of this protein?
May dephosphorylate receptor tyrosine-protein kinase ERBB4 and inhibits its ligand-induced proteolytic cleavage (PubMed:15219672).  May play a role in odontogenesis (PubMed:27843125).
What are the official names of this protein?
Testicular acid phosphatase, Acid phosphatase 4.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RUVA_PARPJ
Sequence: MIGRIAGVLLEKNPPHLLIDCNGVGYEVDVPMSTFYNLPSTGERVVLLTQMIVREDAHLLYGFGTAEERSTFRELLKISGIGARMALAVLSGMSVHELAQTVTMQDAARLTRVPGIGKKTAERLLLELKGKIGADLGAMAGAASASDHASDILNALLALGYSEKEALTAVKNVPAGTGVSEGIKLALKALSKG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ISPH_GEOSW
Sequence: MEVIKITPRGYCYGVVDAMVIARNVALDPTLPRPIYILGMIVHNKHVTDAFAEEGIITLDGENRLEILEKIDKGTVIFTAHGVSPEVKRRAREKGLVTIDATCPDVTKTHNLIKEKLADGYEIIYIGKKGHPEPEGAVGIDPTRIHLVETMEDVERLTIENDRIMVTNQTTMSQWDVADIMAKVKEKYPHVEMHKEICMATQLRQEAVAEQAKDADVTIVVGDPRSNNSNRLAQVSEEIAGTKAYRVADVTEIDINWIKDAKKVAVTAGASTPTPITKEVIDFLEQFDPNDPNTWKRERKVPLQKILPKVKAKKE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: KUP_BURPS
Sequence: MTDTNHSSMRQHSLQSLAIAAIGVVFGDIGTSPLYSLKEAFSPAHGIPLTPSAILGVISLLFWAIILVVGIKYVLFVMRADNNGEGGVLALMALSLRPLNPKSRITGLMMALGIFGACMFYGDAVITPAISVMSAVEGLEVATPQLSHLVLPITIVILIALFWIQRHGTATVGKLFGPIMVLWFVTIAVLGIYHIARAPMIVSAINPYYAFSFMSEHVLLAYVVLGSVVLVLTGAEALYADMGHFGAKPIRLAAYVLVMPSLVLNYFGQGALLLLDPKAIENPFFLLAPQWAALPLVVLSTVATVIASQAVISGAYSLTSQAIQLGYVPRMKILHTSELAIGQIYVPVVNWLLLFVILCIVIGFKSSDNLAAAYGIAVTATMVITTILAAVVMVKVWNWNKLLVAMIIGVFLVIDLGFFGANLLKVEQGGWLPLGIGALLFFLLMTWYKGRHIVKERTAADGIPLAPFLQGLLAHPPHRVSGTAIYLTGNDTLVPVSLLHNLKHNKVLHERTIFMTFVTRDIPYVKDHERVTVHDAGEGLYIVKAEYGFNETPDVKAVLEEVARQRGMTFELMDTSFFLARETVVPTHLPGMSIWRERVFAWMHQNAAKPTDFFAIPANRVVELGTKIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPDA2_MYCTO
Sequence: MAANKREPKVVVLGGGSWGTTVASICARRGPTLQWVRSAVTAQDINDNHRNSRYLGNDVVLSDTLRATTDFTEAANCADVVVMGVPSHGFRGVLVELSKELRPWVPVVSLVKGLEQGTNMRMSQIIEEVLPGHPAGILAGPNIAREVAEGYAAAAVLAMPDQHLATRLSAMFRTRRFRVYTTDDVVGVETAGALKNVFAIAVGMGYSLGIGENTRALVIARALREMTKLGVAMGGKSETFPGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMSQVAEGVKAAGVVMEFANEFGLNMPIAREVDAVINHGSTVEQAYRGLIAEVPGHEVHGSGF
What are the official names of this protein?
Probable glycerol-3-phosphate dehydrogenase 2 [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_OCEIH
Sequence: MAELRAHRIAEQMKKELGEILSRKIKDPRVGFVTVTDVEVTGDLQQAKVYISVLGDEKKKQDTLLGLSKAKGFIRSEIGNRIRLRKTPEITFEFDEALEQGNRIETILRDLNK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPIIB_BLAGS
Sequence: MQLSSVLLTAAGLLAPVYSSAIISIGRRSEGLDVSLASTGNTKVQVSVTNTGSSEISILRANTLFDASPTKKFTVYKEGSRKEVPFKGVHLRRSPSDLAKDNLQPIGPGQTIDKEFDLAETLNLSESGTYIVSADGVFPIIDPKSFSIASVIPYESNELKIEVDGKQVSGVLSTRAKIHDHLAQRADFNNGNCTDHQKAVIASALKRDSSIAGEASNAALSGDVRVFEQYFRTTDPSIRQQVSDRFHAISNEACSAEGGVVKYQCEDEMDVCRPGTVAYALLGSNVVVNCPIYYSVTAVSQACDAGDQALTVIHELSHIDAVYYPATTDLAYGEDASMALNADMSIRNADSYTFYANAVRQNCNPS
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog BDBG_02110, Deuterolysin BDBG_02110.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TXD05_LYCSI
Sequence: MKILFVLISILYAVYCFSSEEDVDSAYLANELEPVEDINSEQYAALEPKEEQERSCADMGQDCKDDCDCCLNIATCNCRFGRYFCSCTFGDYQTCLRKKGKCKRNRPQSCPRSNLNRKKG
What are the official names of this protein?
U13-lycotoxin-Ls1d, Toxin-like structure LSTX-L5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 05 (agouti) family.
What are the subcellular locations of this protein?
Secreted.