PharMolix/UniProtQA huggingface dataset:
Protein: GSA_PSEA6
Sequence: MQKSEQLFARAQKHIPGGVNSPVRAFRAVGGTPPFIEKADGPYLYDADGKQYIDYVQSWGPMVLGHNNPIIRQAVIDAAQNGLSFGAPTEAEVTIADLVSELVPSMEMLRMVNSGTEATMSAIRLARGYTKRDKILKFEGCYHGHADALLVKAGSGALTFGVPSSPGIPADFAKHTLTMEYNNIDSVVQAFEQYPDDIACIIVEPVAGNMNCIPPVHGFLQGLRDVCDKYGAVLIFDEVMTGFRVALGGAQAKYNIVPDLTCLGKVIGGGMPVGAFGGKRDIMQHIAPSGPVYQAGTLSGNPVAMAAGLAALNQVKRPGLYEELSEATKTLAEGIKAIANGLGIPMSVNYAGSMFGLFFTDVECVTNYQQAINCNTEQFNHFYHGMLENGVYLAPASYEAGFVSAQHSPEIIQQTLQIAEKVLADVAKKFG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_DESVH
Sequence: MADTCFRLHTEFEPTGDQPEAIGQIVANLGHGVRDQVLLGVTGSGKTFTVANVIAACNRPALILAPNKTLAAQLYNEFRALFPDNAVEYFVSYYDYYQPEAYVPASDTYIEKDSSINDNIDKLRHAATHALLTRRDVVIVASVSCIYGLGSPEYYARLVIPVECGQRFSMDALMTRLVEVQYQRNDFDFHRGTFRVRGDVLEVIPAYHHERALRIEFFGDDIDAISEIDPLTGEVLGSVGKTVIYPASHYVSDRDNLVRAMSDIRDELGERLREYQSANRLVEAQRLEQRTMLDLEMMEELGYCNGIENYSRHLDGRAAGQPPSCLLDYFPDDFLLFVDESHITVPQVGAMYKGDRSRKSTLVDFGFRLPSALDNRPLEFAEFLTRINQTVYVSATPGKWELDRSQGVIAEQIIRPTGLVDPVVEVRPTRGQVDDLLAECRARAARDERVLITTLTKRMAEDLTEHLGNMGLSVRYLHSDIDTMERMAIIQALRRGECDVLVGINLLREGLDIPEVSLVSILDADKEGFLRSTGSLIQTFGRAARNAAGRVILYADTVTASMRAAMDETARRRERQQAWNEANGIEPRTIRKSLDTPFDAIYSAASEGGKGKGRGRGRQAAPAVENVAEYGTSPEDMAKHIQKLEREMREAAKELEFERAATLRDRIRLLRERLIEA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUB3_BOVIN
Sequence: MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDTEHPEDGIFIRQVTDAETKPKST
What is the function of this protein?
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments.  Promotes the formation of stable end-on bipolar attachments.  Necessary for kinetochore localization of BUB1.  Regulates chromosome segregation during oocyte meiosis.  The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20.  This complex can also phosphorylate MAD1L1 (By similarity).
What are the official names of this protein?
Mitotic checkpoint protein BUB3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BUB3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition.
Protein: CRTP_STAAB
Sequence: MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKKDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGTRVDNIKIYQRHVTGVRLDTGEFVKADYIISNMEVIPTYKYLLHLGTQRLNKLEREFEPASSGYVMHLGVACQYPQLEHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFTKESQYFENLYFVGGSVNPGGGMPMVTLSGQQVADKINAREAKNRK
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes the oxidation of the terminal methyl side group of 4,4'-diaponeurosporene to form 4,4'-diaponeurosporen-4-al.
What are the official names of this protein?
4,4'-diaponeurosporene oxygenase, 4,4'-diaponeurosporene oxidase, Carotenoid oxidase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtP subfamily.
Protein: CWP17_SOLLC
Sequence: MNIPPGD
What are the official names of this protein?
22 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: NADA_WIGBR
Sequence: MSKKKETDSYLSSDIKKSKDFKIISNLLKINDAVIVSHYYTTPDIQAITEATGGKVADSLEMAKFGKNHKAKTLLVAGVRFMGETAKILNPEKIVLMPTLKAECSLDLSCPEKEFNKFCDNHPDRTIVVYANTSAAIKARAHWIVTSSIAIDLIDYLDRLGEKIIWAPDKHLGRYIQKQTGADILIWNGTCIVHDEFKSQSLLNMKKIYPKSAILAHPESPENVLNLADFIGSTSQLIQAAKSINQKTIIIATDKGIFFKMQQACPDKILIEAPTSGEGLTCLSCARCPWMKMNNINRIIKSLTNKKKHNEINIPHDLQKKALKPLMRMLKFSQKVI
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_BARHE
Sequence: MKIKNSLKALRERHRNNRLVRRKGRVYILNKTNPRFRARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: YI7E_SCHPO
Sequence: MSSLSPELYGCLGNSGLKVSKLILGCMSYGKKEYWEDWVLEDEEEVFKIMKAAYDAGIRTFDTANCYSAGVSEELVGKFIRKYEIPRSSIVILSKCFFPVRKDLIKIFGDLSSRGVHFLDSPELANQCGLSRKHIFDAVEDSVKRLGTYIDVLQIHRYDPHVSAEEVMRALNDVVESGKVRYIGASTMRCYQFIELQNTAEKHGWHKFISMQNYHNLLYREEEREMIPYCQKTGVGLIPWSPLARGLLTRSIDANEETIRSKTDLYTRALEFGAGYKAILSRVEELAKKYNVSMATLATAWSLHKGDYPIVGISKVERLKDALAAVELKLSEEDIKYLEEPYCPVPIQGEI
What are the official names of this protein?
Putative aryl-alcohol dehydrogenase C977.14c.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUSB_SALRD
Sequence: MSSRRDAREQVMKTLYANEQTDGDAEQALHALVRVPLDEDPSTRDFAEHLFRETLKTMEEADEIIEKHADNWEIHRIAAIDRSLLRMATTELLKFEEVPPKVSVDEAIEIAKRYSTPRSGTFVNGVIDAILLDLHDQGRLNKTGRGLIGMDTIQERAGSS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: EDN2_MACFA
Sequence: PEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPSCATFCLRRPWTEARAVPSRKSPADVFQTGKTGATRGELLQRLRDIS
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides.
What are the official names of this protein?
Endothelin-2, ET-2, Preproendothelin-2, PPET2.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTD_METKA
Sequence: MTVAKAIFIKCGNLGTSMMMDMLLDERADREDVEFRVVGTSVKMDPECVEAAVEMALDIAEDFEPDFIVYGGPNPAAPGPSKAREMLADSEYPAVIIGDAPGLKVKDEMEEQGLGYILVKPDAMLGARREFLDPVEMAIYNADLMKVLAATGVFRVVQEAFDELIEKAKEDEISENDLPKLVIDRNTLLEREEFENPYAMVKAMAALEIAENVADVSVEGCFVEQDKERYVPIVASAHEMMRKAAELADEARELEKSNDAVLRTPHAPDGKVLSKRKFMEDPE
What is the function of this protein?
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
What are the official names of this protein?
F420-dependent methylenetetrahydromethanopterin dehydrogenase, MTD, Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MTD family.
Protein: PP2C3_PARTE
Sequence: MGPYLSQPKREKVTTSGEGKSVIFAASEMQGWRNTMEDAHIHRPDIVQDVSVFGVFDGHGGREVAQFVEKHFIDELLKNKNFKEQKFEDALKETFLKMDELLMTPEGAKELNNYKATDTDESYAGCTANVALIHKNTLYVANAGDSRSVLCRNNTNFDMSVDHKPDNNEEKSRIERAGGFVSDGRVNGNLNLSRALGDLEYKSDSKLRPNEQLIIAFPDVKKTELTPQDKFILMGCDGVFETLNHQELLKHVNTTLGNSPVTENLLSKAAEDLLDQLLAPDTSQGTGCDNMTTILVYLKK
What is the function of this protein?
Enzyme with a broad specificity.
What are the official names of this protein?
Probable protein phosphatase 2C 3, PP2C 3.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: MI40B_XENLA
Sequence: MSYCRQEGKDKIIFVTKEDHETPSSAELIADDPNDPFEEQGLILPNGDINWNCPCLGGMASGPCGEQFKSAFSCFHYSQEEIKGSDCLDQFRAMQECMQKYPELYPQEDDEDELEKEKQNKDEESSVTQSSDTKEESSS
What is the function of this protein?
Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity).  Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1.  Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS).  Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.
What are the official names of this protein?
Mitochondrial intermembrane space import and assembly protein 40-B, Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-B.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: FBF1_CHICK
Sequence: MATKSKSSVRGSIDDVLDDLLGYDDEGPAKSSQPAGVSSGRARGSSLQASKKSFLEDDFFSKLPAEDMEAAEGSSISDADPQAVLQTLKEMDDMEADLLGMSKPSSGLGKAATKGPGKFSTSEGAVKTSGKMPAPEKGESAPEMDKKPLSSPPTSRQYRKFNFEDVDDPLAGLLSEEEQDAPRKPSPKGSERRPERKTELGKEKDPLPPQTPLHTTAPARRREELTFEDDDDDMMDVLGFGDGQKGDQKHGKKAEEEEVRPARSKLDELLGRGSVAKILERPGAGEHREFKLDKKYQKQPEKEEGWDEEDFVFGAYQPTVATTPEGRPSRRQSVSRFSAENSSEPKPDPHSKPPPAASQSPARGSRAGGDWLGLKDEDFLDSEPPSPAKTSPVVSSQQLLAKEQATSKPNQLEEDNWLSAALSRKKAQAQVKAQERGAVPLETTGKGLDPSPAVSQPATSTGAAAQAAALQDKAASADSSGHPVPWLSTVTQTSAHPPEPAKRDPLRDVSPSDPAASSPAEQGMQGPAPLAQVTMPSTPLQAASQLQAESPPLGSVHERRPGAPTGQSYEDATGCRAALLSAQARVAELESQVRMLELERTQHKLLLESLQQRHQEDLDLLESAHRSRVKVVEETYGQREERLRREKEQLEAQLLSQSQDAERARADLVAQHKQRVATLEQQSAQELERLRELQRSSVQEMLKDHEEQLQRLKRLKDQEIDAVTSATSHTRSLNGVIEQMERFSSDLHSLSHKVEATHHTTSQELAMGARQRDEQLKVLQDRLSQQQRDMEEERSRLQEVIAKMEARLSEQTRLLEQERWRVTAVQSKVESLQRSLEEQRRLMTQQLSMERAELERAKSALLEEQKSVMQKCSEERRKLAVEWAEFHTQQQLSKERMERDIDRALQLDSQREGTIMSLAKEQAELKVRSRELKVKEEQLARDRLLLDEAWHELRLEKEKVKGATLRIRQQEEEIKNMSKLSAQKYEEGERALQDACRIESEHQARLQVMQQHLEQLKQQEQHLQQERLSMAHQRRQLEQLHKKLPNNPTLLLTTDQDLSASTKGLSSTLSFPPPIRTLPGHRSVGTTASMELYAKLLVLKHRAQQDRNFLEDEQLFLETLKKASYNTSPLSV
What is the function of this protein?
Keratin-binding protein required for epithelial cell polarization.  Required for ciliogenesis (By similarity).
What are the official names of this protein?
Fas-binding factor 1 homolog, FBF-1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell junction. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to the apical junction complex (AJC) in epithelial cells (By similarity).
Protein: AZOR_STAA1
Sequence: MAKVLYITAHPFNELVSNSMAAGKAFIETYQQHHPDDEVKHIDLFETYIPVIDKDVLTGWGKMSNGETLTDDEQMKVSRLSDILEEFLSADKYVFVTPMWNLSFPPVVKAYIDAISIAGKTFKYSAEGPQGLLTDKKVLHIQSRGGYYTEGPAADFEMGDRYLRTIMTFLGVPSYETIIIEGHNAEPHKTEEIKATSINNAEKLATTF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: CMT2_ARATH
Sequence: MLSPAKCESEEAQAPLDLHSSSRSEPECLSLVLWCPNPEEAAPSSTRELIKLPDNGEMSLRRSTTLNCNSPEENGGEGRVSQRKSSRGKSQPLLMLTNGCQLRRSPRFRALHANFDNVCSVPVTKGGVSQRKFSRGKSQPLLTLTNGCQLRRSPRFRAVDGNFDSVCSVPVTGKFGSRKRKSNSALDKKESSDSEGLTFKDIAVIAKSLEMEIISECQYKNNVAEGRSRLQDPAKRKVDSDTLLYSSINSSKQSLGSNKRMRRSQRFMKGTENEGEENLGKSKGKGMSLASCSFRRSTRLSGTVETGNTETLNRRKDCGPALCGAEQVRGTERLVQISKKDHCCEAMKKCEGDGLVSSKQELLVFPSGCIKKTVNGCRDRTLGKPRSSGLNTDDIHTSSLKISKNDTSNGLTMTTALVEQDAMESLLQGKTSACGAADKGKTREMHVNSTVIYLSDSDEPSSIEYLNGDNLTQVESGSALSSGGNEGIVSLDLNNPTKSTKRKGKRVTRTAVQEQNKRSICFFIGEPLSCEEAQERWRWRYELKERKSKSRGQQSEDDEDKIVANVECHYSQAKVDGHTFSLGDFAYIKGEEEETHVGQIVEFFKTTDGESYFRVQWFYRATDTIMERQATNHDKRRLFYSTVMNDNPVDCLISKVTVLQVSPRVGLKPNSIKSDYYFDMEYCVEYSTFQTLRNPKTSENKLECCADVVPTESTESILKKKSFSGELPVLDLYSGCGGMSTGLSLGAKISGVDVVTKWAVDQNTAACKSLKLNHPNTQVRNDAAGDFLQLLKEWDKLCKRYVFNNDQRTDTLRSVNSTKETSGSSSSSDDDSDSEEYEVEKLVDICFGDHDKTGKNGLKFKVHWKGYRSDEDTWELAEELSNCQDAIREFVTSGFKSKILPLPGRVGVICGGPPCQGISGYNRHRNVDSPLNDERNQQIIVFMDIVEYLKPSYVLMENVVDILRMDKGSLGRYALSRLVNMRYQARLGIMTAGCYGLSQFRSRVFMWGAVPNKNLPPFPLPTHDVIVRYGLPLEFERNVVAYAEGQPRKLEKALVLKDAISDLPHVSNDEDREKLPYESLPKTDFQRYIRSTKRDLTGSAIDNCNKRTMLLHDHRPFHINEDDYARVCQIPKRKGANFRDLPGLIVRNNTVCRDPSMEPVILPSGKPLVPGYVFTFQQGKSKRPFARLWWDETVPTVLTVPTCHSQALLHPEQDRVLTIRESARLQGFPDYFQFCGTIKERYCQIGNAVAVSVSRALGYSLGMAFRGLARDEHLIKLPQNFSHSTYPQLQETIPH
What is the function of this protein?
May be involved in the CpXpG methylation and in gene silencing.
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase CMT2, Chromomethylase 2, Protein CHROMOMETHYLASE 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_YERE8
Sequence: MATVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPLFNEALAELKKISSRKGKILFVGTKRAASEAVKEAANNCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLEIQSQDGTFDKLTKKEALMRTRELNKLENSLGGIKDMGGLPDALFVVDADHEHIAIKEANNLGIPVFSIVDTNSDPDGVDFIIPGNDDAIRAVKLYLNAVADAVKEGRSQDLAVQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: LLCD_SYNY3
Sequence: MLTAERIKFTQKRGFRRVLNQRVDAYFAEHGLTQRDNPSMYLKTLIIVLWLFSAWAFVLFAPVIFPVRLLGCMVLAIALAAFSFNVGHDANHNAYSSNPHINRVLGMTYDFVGLSSFLWRYRHNYLHHTYTNILGHDVEIHGDGAVRMSPEQEHVGIYRFQQFYIWGLYLFIPFYWFLYDVYLVLNKGKYHDHKIPPFQPLELASLLGIKLLWLGYVFGLPLALGFSIPEVLIGASVTYMTYGIVVCTIFMLAHVLESTEFLTPDGESGAIDDEWAICQIRTTANFATNNPFWNWFCGGLNHQVTHHLFPNICHIHYPQLENIIKDVCQEFGVEYKVYPTFKAAIASNYRWLEAMGKAS
What are the official names of this protein?
Acyl-CoA 6-desaturase, Delta(6)-desaturase, Linoleoyl-CoA desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
Protein: COLY_YERPE
Sequence: MKKSSIVATIITILSGSANAASSQLIPNISPDSFTVAASTGMLSGKSHEMLYDAETGRKISQLDWKIKNVAILKGDISWDPYSFLTLNARGWTSLASGSGNMDDYDWMNENQSEWTDHSSHPATNVNHANEYDLNVKGWLLQDENYKAGITAGYQETRFSWTATGGSYSYNNGAYTGNFPKGVRVIGYNQRFSMPYIGLAGQYRINDFELNALFKFSDWVRAHDNDEHYMRDLTFREKTSGSRYYGTVINAGYYVTPNAKVFAEFTYSKYDEGKGGTQTIDKNSGDSVSIGGDAAGISNKNYTVTAGLQYRF
What is the function of this protein?
Seems to play an essential role in plague transmission by mediating flea blockage in a temperature-dependent fashion.  Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (<30 degrees Celsius).  Activates plasminogen by cleaving it.
What are the official names of this protein?
Coagulase/fibrinolysin, Plasminogen activator.
What is the protein family that this protein belongs to?
Belongs to the peptidase A26 family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RR2_NEOYE
Sequence: MAIVTLAELLEAGVHFGHQARRWNPKMFPYIYTERNGIHIIDLVQTAQLLTEACELIKQASSDGKKVLFLGTKRQAAGIVAQEAQRCDSYYVNQRWLGGMLTNWVTIKSRVSRLRQLEEQDKSGMIDQLPKKEAAVLRRELDKLRKHLNGIKNMTRLPDIVVVVDQKRETTAIQECLKLGIPTICILDTNCSPEIINIPIPANDDAIRSIKLIVGKIADAIYDGKYGQTDLEEITHPTQSEL
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 6PGD1_YEAST
Sequence: MSADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISKLKRPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAKSDGEPCCEWVGPAGAGHYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEITRDILKFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASKVLPGPEVPKDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALMWRGGCIIRSVFLGQITKAYREEPDLENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECASDNLPVDKDIHINWTGHGGNVSSSTYQA
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating 1.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_PROMP
Sequence: MIDKQVIVIGAGLAGCEAAWQIANSGIAVKLVEMRPLNSTPAHHTSEFAELVCSNSFGALSADRAAGLLQEELRTFNSLIIQTADKFSVPAGGALAVDRSKFSKSLTQTLSAHPFVEISRFEQLDLPNKKNITVLATGPLTSDELATKIKKFTGIDSCHFFDAASPIIYGDSINHEIVFKASRYDKGDPAYLNCPINKLDYFNFRNALINGEQASLKDFDKESANFFEACLPIEEIARRGIETMRYGPLKSIGLWNPNWGDLFDRENRLKKRPHAIVQLRKEDLEGKLLNMVGFQTNLKWSEQKRIFRMIPGLEKAEFVRFGVMHRNTFLESPKLLLPTLQFLKRETLFAAGQITGTEGYAAAAAGGLLAGINASLLAKNKNLVTFPNESMIGSLMNFISNRNEIMSNQKKNKFQPMPASFGLVPELTNKIKDKKLRYKAYQERSLKELQVFKKVLDASFKNDQLLVEIN
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEPA_ECOBW
Sequence: MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVSTLWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPSGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DCUP_SHESR
Sequence: MAELKNDRYLRALLKQPVDMTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNHELACEVTLQPLRRYELDAAILFSDILTVPDAMGLGLYFEAGEGPRFERPTDTIDAIKKLAVPDPEDDLGYVMKAVSTIRRELNGQVPLIGFSGSPWTLATYMVEGGSSKTFEKIKKMAYAEPAALHMLLDKLADSVTLYLNAQVANGAQSLMIFDSWGGALSHTAYREFSLRYMQKIVDGLTRFADGRQVPVTLFTKGGGLWLEAMAETGCDALGLDWTVDIADARRRVGHKVALQGNMDPSMLYAPIPRIEEEVAQILAGYGEGTGHVFNLGHGIHQHVDPEHAGAFIKAVHAQSKQYHK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRA_BORBU
Sequence: MAVGENKEQILNVRIEDEIKTSYLNYAMSVIVSRALPDVRDGLKPVHRRILYSMYEMGLRSDKAFKKAGRIVGDVLGKYHPHGDQSIYDALVRLAQDFSLRYPVIRGQGNFGSIDGDPPAAMRYTEAKMEKITEYIVKDIDKETVNFKSNYDDSLSEPEIMPSSFPFLLVNGSSGIAVGMATNMAPHNLREICDAIVYMLDNENASIFDLLKIVKGPDFPTFGEIVYNDNLIKAYKTGKGSVVIRARYHIEERAEDRNAIIVTEIPYTVNKSALLMKVALLAKEEKLEGLLDIRDESDREGIRIVLEVKRGFDPHVIMNLLYEYTEFKKHFSINNLALVNGIPKQLNLEELLFEFIEHRKNIIERRIEFDLRKAKEKAHVLEGLNIALNNIDEVIKIIKSSKLAKDARERLVSNFGLSEIQANSVLDMRLQKLTALEIFKLEEELNILLSLIKDYEDILLNPVRIINIIREETINLGLKFGDERRTKIIYDEEVLKTSMSDLMQKENIVVMLTKKGFLKRLSQNEYKLQGTGGKGLSSFDLNDGDEIVIALCVNTHDYLFMISNEGKLYLINAYEIKDSSRASKGQNISELINLGDQEEILTIKNSKDLTDDAYLLLTTASGKIARFESTDFKAVKSRGVIVIKLNDKDFVTSAEIVFKDEKVICLSKKGSAFIFNSRDVRLTNRGTQGVCGMKLKEGDLFVKVLSVKENPYLLIVSENGYGKRLNMSKISELKRGATGYTSYKKSDKKAGSVVDAIAVSEDDEILLVSKRSKALRTVAGKVSEQGKDARGIQVLFLDNDSLVSVSKFIK
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state (PubMed:15897198).  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXD12_CARPS
Sequence: MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWATTPASCAPAQPAGATAFGSFSQPYLAGSGPLGLQPLGAKDRPEEQAKFYTPDVAAGPEERGRSRPPFAPESSLVPGTAGLKSTKYDYAGVGRAAPGSAALLEGTPCAAGFKDDAKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLLNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALALY
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D12.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBFA_SHIFL
Sequence: MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLHRVWSKTSDKPVWMDQAEKATGDFY
What are the official names of this protein?
Uncharacterized protein YbfA.