PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_PAEAT
Sequence: MLGIESSCDETGVGIVRGTTLLTNTVSSSMDEHVRFGGVIPEIASRAHLDAFVPTLQESLQEAGVTLEDIDAIAVTSGPGLAGALMVGVCAAKALAVATGKPLYAINHLVAHVGVGLLDGNRVSEGKHDAVAAAGLGAGKLPENLGALLVSGGHTEILRIRSITDDVELLGSTIDDAAGEAYDKVARILGLGYPGGPAIDKLAHQGNPKSIRFPRGLTQPKYMGTAEEKGPHRYDWSFSGLKTAVARCVEQFEARGEEVPVADIAAAFQEAVVDVISSKAVLACKEHGITDVLLGGGVAANSRLRELTGQRCASAGITLHVPPLGLCTDNGAMVAALGAQLIMAGISPSGVSFAPDSSMPVTTVSVPA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_DESOH
Sequence: MNIVLTNDDGIDAEGLLALYRVFSRDHRVVVVAPEAERSAVGHGISLHQPLRVNQRNHPAGGEWYAVSGTPADCVKLGILALLDPRPDLVISGINAGLNHGAYMHYSGTVAAAREACVYGVPSIAVSMDGYPPAYFDEGASLTQTLVERLAEMEMPANTFLNVNMPDLPRERITGICFCSQDVLPPGDRVDMRNDPRGLAYYWYAYDNTHGDGTGDTDRAMLRNGTVSITPVTCDGTHYGVLERLKQFSLDL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_MYCS2
Sequence: MGLDLSADPIALTAALVDIPSVSRDERRIADEIEAALRAQAPHFEVIRNGDAVLARTNLGRPSRVMLAGHIDTVPIADNLPSRIVDGEMYGCGTSDMKAGDAVFLHLAATITEPTHDITLVMYDCEEIESSANGLGRIERELRDWLTADVAILGEPSGGYIEAGCQGTIRVVISAKGTRAHSARSWLGDNAIHKLAPVLDRLASYQARSVDIDGCVYREGLSAVRIDGGIAGNVIPDAASVTVNFRFAPDRDVDQAVAHVHEVFDGLDVTLELTDAAAGALPGLTQPAAAALVAAAGGQVRAKYGWTDVARFAALGIPAVNYGPGDPNLAHRVDERVQVAAITAAADMLRTYLTT
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CLPP_CLONN
Sequence: MSLVPVVVEQTNRGERSYDIYSRLLKDRIIFLGEEVNDVTASLVVAQLLFLEAEDPDKDIYLYINSPGGSITAGMAIYDTMQYIKPDVSTICIGMAASMGAFLLTAGAKGKRFALPNSEIMIHQPLGGFQGQATDIGIHANRILKIKDKLNSILSERTGQPLEVIKKDVERDNFMEAEEAKEYGLIDDVITSRKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXK3_RAT
Sequence: MAAIEPSGLHPGERDSSCPQEGIPRPSGSLELAQEYLQQFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKEHSVETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNIDVVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGVLFGGCASPALLSQNSILLEHVAKMEDPATGIAHVHTVLQGLGLSPQASDAELVQRVCMAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETVMLLAPECDVSFIPSVDGGGRGVAMVTAVAARLATHRRILEETLAPFQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVAEGSVQITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLSGQSLPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTVGTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPGDSGHMCINMEWGAFGDDGSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQCLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLTLTSDDALMVLEVCQAVSRRAAQLCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTVRKLAPQCTVTFLQSEDGSGKGAALVTRVACRLTQMACV
What is the function of this protein?
Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:5871820).  Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed:5871820).
What are the official names of this protein?
Hexokinase-3, Hexokinase type III, HK III, Hexokinase-C.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
Protein: CLPX_CHLCV
Sequence: MNKKNLTICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKKPTSTPSSGTPTETTPQHSDLQVLTPKEIKKHIDKYVVGQERAKKTIAVAVYNHYKRIRALLNNKHVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDVENIVLRLLQAADYNVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIIEGTTANVPPKGGRKHPNQEYIRVNTENILFIVGGAFVNLDKIIAKRLGKTTIGFSDDLGDFSQEDRDHLLTKVETEDLIAFGMIPEFVGRFNCIVNCEELSLDELVAILTEPTNAIVKQYIELFSEENVKLIFEKDALYAIAKKAKLAKTGARALGMILENLLRDLMFEIPSDPTVEAIRIQEDTILENKAPVIIRRTPEAIA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SWAHB_XENLA
Sequence: MAKELSQEEVLDFLCQSGGKVANASLLVHFKRFLRDPQAADAVLLKRRDKFKRYINSVAVVRQEGSVKYVVLRNRYQDLLGEDIEPAAAEDAGSEGERDQVVLPTEHGQDYLAHTFGQERLKQANGGDVICDCSEARAVVPSAAPHSHSQSWDVGESMSEKARVNPSHWDTKRYYPEDPPVPDSLPVSPPCTNTRQSSFTSTSRPHNHSLSSNNLSSSFSSPESPGLVAKPYNASPSPAGSSPNIREQTPKSQSLSKAANAAFVSVTCTDIKEQREGCTELLAPQPCQNWDYSQPEQLHSAQEHHSDLHREHMTNGFHSPDPLSSKYPHLTSPCTPLQLSPETDTTPDVPLAHNLAAVSYPSPPLPGNNMYGMWMCQIPVFKSIRCQLSLQDLDDFVDQETCGSEESDSGEGGDCDTEPRDNDDADDDTFSSDSHKEIPKLCVEQESEYLHKCHSNIDYSGKNDLYNSLLEEDRIGVKDTLVEHGDVASMRIDTSKSVYTAKSFLTDQAPILFELVRNAPPNKTSSCFQGALSSSDEELLDRDYRKRRRSSRYKKSANVSVPCVQPDTDRLLTAKCVSSSSFLINNNLQEQSTQAQFLPKYNSNFGLKKSASQKSSVVPLDPKEHDWIVKTAAGLWIQVYGMFSMDPHLALHKDFITGYTALHWFAKHGCIDLFNKVVIGAKKAGIELDMNVKSSNGYTPLHIAAIHGHHKVAIMLVEKLKVNVKVRDNSGKRAWQYLNSATSGDVWQLLGAPKGKTIFASCALHTAQNLNIRNKTSSQLARKSSLAAFRKTQHQRRKANNQSFLREREIYSD
What are the official names of this protein?
Ankyrin repeat domain-containing protein SOWAHB, Ankyrin repeat domain-containing protein 56, Protein sosondowah homolog B.
What is the protein family that this protein belongs to?
Belongs to the SOWAH family.
Protein: VM3FA_VIPAA
Sequence: LVSVSPAFNGNYFVE
What is the function of this protein?
Catalytic subunit of blood coagulation factor X-activating enzyme.  Activates coagulation factor X (F10) in a calcium-dependent manner by cleaving at the '234-Arg-|-Ile-235' site.  Weakly hydrolyzes insulin B chain (by cleaving at the '27-Asn-|-Gln-28' and '44-Gly-|-Glu-45' sites), fibrinogen and some components of the extracellular matrix in vitro.
What are the official names of this protein?
Factor X-activator 1 heavy chain, VAFXA-I HC, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIId sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS27A_NITMS
Sequence: MAGKKGSSPNVYAYFKVDGDKVSRIKKVCSRCGKGTYMSEHKDRNTCGKCGLTEFKQ
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: RS10_CHLCV
Sequence: MKQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVAGPIPLPTKREVYTVLRSPHVDKKSREQFEIRTHKRLIDILDPTGKTIDALKMLALPAGVDIKIKAA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DNAK_GEOKA
Sequence: MSKIIGIDLGTTNSCVAVLEGGEVKVIPNPEGNRTTPSVVAFKNGERLVGEVAKRQAITNPNTIISIKRHMGTDYKVEIEGKQYTPQEISAIILQYLKSYAEDYLGEPVTRAVITVPAYFNDAQRQATKDAGRIAGLEVERIINEPTAAALAYGLDKEEDQTILVYDLGGGTFDVSILELGDGVFEVKATAGDNHLGGDDFDQVIIDYLVNQFKQEHGIDLSKDKMALQRLKDAAEKAKKELSGVTQTQISLPFISANENGPLHLEMTLTRAKFEELSAHLVERTMGPVRQALQDAGLTPADIDKVILVGGSTRIPAVQEAIKRELGKEPHKGVNPDEVVAIGAAIQGGVIAGEVKDVVLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFTTAADNQTTVDIHVLQGERPMAADNKSLGRFQLTGIPPAPRGVPQIEVTFDIDANGIVHVRAKDLGTNKEQSITIKSSSGLSEEEIQRMIKEAEENAEADRKRKEAAELRNEADQLIFMTDKTLKEVEGKVSADEIKKAQDAKEALKAALEKNDIDDIRKKKDALQEAVQQLSIKLYEQAAKQAQSAGSQGGAANHKDNVVDAEFEEVNDDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NU3C_AETGR
Sequence: MFLLYEYDIFWAFLIISSAIPFLAFLISGVLSPIRKGPEKLSSYESGIEPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSAFIEAFVFVLILILGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COAE_FUSNN
Sequence: MSIMIIGLTGGIASGKSTVSKYLAEKGFKVYDADKIAKDISEKKSVQEEIISTFGNKILDKNGNIDRKKLKEIVFENKEKLEKLNGIIHPKVINFYKELKEKKTDKVIIFDVPLLFESGIDKFCDKILVVISDYEVQLNRIIERDKINRELAEKIIKSQLSNEERIKKADVVIENNSNLEDLFKKVERFCETI
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUIP_PSEAE
Sequence: MASPAFMRFLPRCGAAAAFGTLLGLAGCQSWLDDRYADSLPPTSGVQPIKGLAQNVSIRRNALGMPLIETGTFHDALFALGYVHASDRLSQMVSLRLLAQGRLAEMVGPGALEIDRFMRTVNLRQAAEIQYRNASPRLQRFFEVYARGVNAYLYRYRDKLPMDLAQSGYRPEYWKPEDSALVFALLNFGLAVNLQEEIASLTLAQKVGSDKLAWLTPTYPDENLPFDEAEKLKGLRLDGQVPGLAGVEGAARQVAALSMLGVAASNNWAIAPQRSRSGKSLMANDTHLPLSMPSVWNYVQIRSPKYQAAGVSIAGLPGVVAGFNGKLAWGMTMVLGDNQDLYLEQLRRQGNRLYYLADGKWQPTRERQETFFIKGQRPIREVIHETRHGPLLNSALGERKNILQPLPLKSGYGLAYRSIQQEADKTLDGFFDLSRAKTIEQAFDATREIRAMPLNIVFADEKHIGWQVTGRYPNRKEGRGLLPSPGWDGRYDWDGYADPILHPSDQDPQQGWLGTANHRTVQPGYGAQLSNSWYYPERAERIAQLAGASKSHDTQSMIRMQYDQTSLFVAKLQAMFDNPGMALPLRQAIDALPEAQRSRAREAYDRLMAFDGKLTASSSDAALYGAFLHESARQIFLDELGPEDGPAWKAFVETANLSYSAQADHLLGRDDSPFWDDTRTPQKEDKPAILARSLAAAVEFCEQRLGSERKAWQWGKLHTYEWQSDSSKMAPYLGAGERAGLGAIKGYLDRGPYPAGGDHTTLDVSAYGWGQDFDTWLIPAMRLIVDFGQSEPMIGVNSSGQSGNPASPHYADGIDAWLKGRYVSFPFQPQNLDRVYGNKRLTLTPAR
What is the function of this protein?
Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid.  Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in length).  Appears to be the acyl-HSL acylase that underlies the ability of P. aeruginosa to degrade and utilize certain acyl-HSLs as growth nutrients, including one of its own quorum signals, 3-oxo-C12-HSL.  Is thought to have a role in quorum quenching.
What are the official names of this protein?
Acyl-homoserine lactone acylase QuiP, AHL acylase QuiP, Acyl-HSL acylase QuiP, Quorum signal utilization and inactivation protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S45 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TAL_STRPQ
Sequence: MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIKEICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGIKTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEIIAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMM5_ECOLX
Sequence: MKLSPKAAIEVCNEAAKKGLWILGIDGGHWLNPGFRIDSSASWTYDMPEEYKSKIPENNRLAIENIKDDIENGYTAFIITLKM
What is the function of this protein?
This protein is able to protect a cell, which harbors the plasmid ColE5 encoding colicin E5, against colicin E5.
What are the official names of this protein?
Colicin-E5 immunity protein, ImmE5, Microcin-E5 immunity protein.
Protein: PDUE_SALTY
Sequence: MNTDAIESMVRDVLSRMNSLQGDAPAAAPAAGGTSRSAKVSDYPLANKHPEWVKTATNKTLDDFTLENVLSNKVTAQDMRITPETLRLQASIAKDAGRDRLAMNFERAAELTAVPDDRILEIYNALRPYRSTKEELLAIADDLENRYQAKICAAFVREAAGLYVERKKLKGDD
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Propanediol dehydratase small subunit, Diol dehydratase small subunit, DDH small subunit, Propanediol utilization protein PduE.
What is the protein family that this protein belongs to?
Belongs to the diol/glycerol dehydratase small subunit family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=Probably located inside the BMC shell.
Protein: NBPF4_HUMAN
Sequence: MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVASPTEAACPQGTWSGDLSHHQSEVQVSQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPPQLEDDALEGSASNTQGRQVTGRIRASLVLILKTIRRRLPFSKWRLAFRFAGPHAESAEIPNTAGRTQRMAG
What are the official names of this protein?
Neuroblastoma breakpoint family member 4.
What is the protein family that this protein belongs to?
Belongs to the NBPF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_STAAW
Sequence: MKAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIRTVRKTIARLKTVAREREIEQSKANQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL6_LARHH
Sequence: MSRVAKNPVILPAGVEAKFTAAEIVVKGPLGQLAMPLNAGVEVRLEDNALKFAAKDESKASRSMSGTMRALVNNMVTGVSKGFERKLQLVGVGYRAQAQGAALNLTLGFSHPVVHPMPEGVAVETPSQTEIILKGVDKQKVGQVAAEIRAYRAPEPYKGKGVRYAGEQVVLKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: Y2119_PSYCK
Sequence: MAIKDWHEDDRPREKLLKFGAAHLSDAEILAIFLRTGTQSQSAIELARHLIEQFGSLAELLAAPQETVLACHGIGPAKYAQILASLEMGRRYLDSQLKTGQGLGRSQMVKDYISTQLRGEPREVFAVLCLDNALNLINFEILFTGGISSCSVCIKHVLRHALSHAASQLIIAHNHPHTDAKPSTADNLLTYELKKACDLIDLSLIDHVIVGRNETLSYAENSLPPFN
What are the official names of this protein?
UPF0758 protein Pcryo_2119.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: SHC4_MOUSE
Sequence: MRERSQDSQAGLTLYVGLFGHLGMLHRTKYSRFRNESITSLDEGSPGGSVGNKGSSPPPYPALAPHLPTEDATVSSQESPTALCTLIPRMASMKLANPITFLGLKTFCLGTKQVSRLKLQENQDQTPSRPASPESNLNRTGPAPAPDPDQVGRRPTSLRPDTCPLPGPGEPSPRSKQDGPPLQHLLGNGLNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGAHGAIKKRKAPVKFLTTVLGKSNLQFSGMNIKLTVSTSSLTLMNLDNQQIIANHQMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRSGMAQDVISTIGQAFELRFKQYLKNPSLNTWEREEVLVDGAPEDRDHDYYNSIPGKQPPEGGISDVRIQAQATDQMAYCPIRCEKLCYLPGNSTCSGVYKNCMGRSRPIGIPHERAGQGDTPSLRHFWRVDLFDDPCYVNTQALQSMHSYAGNQSSALPQGSPWHLGKAPETVQPGATAKPGSALALPHIRQQLWDEECFHGKLSRGAAEKLLVKDGDFLVRESVTSPGQFVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNNLPIISSGSEVRLKQPIRKYDNTGLLPPKK
What is the function of this protein?
Activates both Ras-dependent and Ras-independent migratory pathways in melanomas.  Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
What are the official names of this protein?
SHC-transforming protein 4, Rai-like protein, RaLP, SHC-transforming protein D, mShcD, Src homology 2 domain-containing-transforming protein C4, SH2 domain protein C4.
What are the subcellular locations of this protein?
Postsynaptic cell membrane. Note=Colocalized with MUSK at the neuromuscular junction.
Protein: DUT_BLOFL
Sequence: MKIINIKIIRNNINNFSLPQHITPGSAGLDLLACIEKPVSILPKETRLIPTGIAIYIEDIEVAGIILPRSGLGHYYGIVLGNTIGLIDSDYQGEIMISLWNRGSNKFILYPGKRIAQLLFISILRVKLSLVKSFDPFMKTIRGVKGFGHSM
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: DDL_THEP3
Sequence: MEKKKIAVLFGGQSGEHEVSLMSAKSIINNLDKDKYEIYMVGITKKGEWYLYRGDVGKIETGEWEKEGIPAIMGASTKYRGIITFEDGENGFYPIDVVFPVLHGPNGEDGTIQGLLELLDMPYVGANVLSSALCMDKVFTKRIFKEAGLPTPDFVVVYGKEIEDLEAIKKKIEHLGYPCFVKPANLGSSVGITKVHNEEELPGALKLAAKYDRKLLIERGIDAREIECSVLGNENPEASIAGEIVPSNEFYDYNAKYFDGGKSLLLIPAPLPDEKMEEVRKLAIKAYKALDLRGMARVDFLMDRNTGTLYLNEVNTIPGFTKISMYPKLWESSGKSYSTLLDELINLAVESHNEKCREW
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_BUCAP
Sequence: MIINLQELIALLPFLILLLTVVIVILSISYNRNHFFIAFLTIISLIVSLCSLYFLIAIVPIDITSLFHITKRSILYISMIIISSIATCVFAYPWLLKYAFNKEEFYLLTLISTLGAIFLTISNHMASLFISVELMSLPIFGLIAYSNSQKYSLEASFKYLVLSGVSSSFLLLGISWIYAISGNLSLLCLNQIFSDLSNSEKMMVLFGIIMVLMSFFFKLSMVPFHLWTADIYQGTPASVLSFFSVSGKIAIFSILLYFFSYFSVFDNKVIFLILSLISFFSILFGNLMAIFQTNIKRFFGYSSISQIGYLLIILLVSKDEYFFSVQTGGIFLLNYLCTNIVYFGVINLFSNSCDYDIDSIHLYKGLFWVQPLLASIVTIVLLSLGGIPITLGFFGKFCIFSIIIKNHLWTIGASFLIGTILGLYGYLRLIVNMYLNPSEQSFINDIKKSNFWLCSPSGILIFISGIMLLILGIYPNPLINLINSVQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTNB_BACCZ
Sequence: MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAETILHTHIYNNTNAGCVLHIHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDSGAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: ASTE_ECODH
Sequence: MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGVLPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFGQNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFMPFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: ATPG_YERPS
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQERMAASRPYAETMRSVIGHLALGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKRLLAEMKGWSEKGVECDLALIGSKAASFFGSVGGKIVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVNNKFINTMSQEPRIMQLLPLPPAEDGELKKKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVGGASAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS6_PROM4
Sequence: MVALRLIPCLDVANGRVVKGVNFVGLRDAGDPVELAYRYSKSGADELVFLDIAASHEGRATLIEIVRRTAESVTIPFTVGGGISSIEGIKELLRAGADKVSLNSSAVRDPELIAQGANQFGSQCIVVAIDAKRRENCTSEWDVFVNGGRKNTKLDALEWAKKVAGLGAGEILLTSMDGDGTQNGYDLKLTRTIADALQIPVIASGGAGSLEHILEAFTEGKASAALLASLLHDGELTIEQIKDYLLKNQLLIRPVLDM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.