PharMolix/UniProtQA huggingface dataset:
Protein: DAPD_CUTAK
Sequence: MTQTTTSQTASADRRAWGWGLATVHEDGGVLDTWYPEPQLGCPDDSSAPADLHRVTEAGRDAIRNVHTEVVHTVIDLDAAPVDVSDAYLRLHLLSSRLAIPRTINLDGIFGVLPNNAWTTIGPIRMADLEKARMEARIAHAPFTVLLIDKFPRMVDFVVPTGVRIGDADRVRLGAHLAVGTTVMHEGFVNFNAGTLGHSMVEGRISQGVIVGDGTDIGGGASIMGTLSGGGKERVTIGRGCLLGAEAGIGISLGDNCVVEAGLYVTAGTKVTLPNGKVVKASELSGASDILYIRDSTTGIVKARGRGNHKIELNSDLHQN
What is the function of this protein?
Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPD1_RIEAN
Sequence: MVISDLEKYYGKPYNNAYYEISNILQEFGFFRTQGSVYLNNNSDMANLMEAIQTLSEVEWFANSVRDIRGFRVEDWSNFTKLVKRKATN
What is the function of this protein?
Cleaves ssRNA, mostly between U:A.
What are the official names of this protein?
Endoribonuclease VapD 1, Virulence-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the VapD ribonuclease family.
Protein: FOXI2_HUMAN
Sequence: MATYCDDLGPSSAPPGQAQATAHPPGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPYAAPSYGAPGPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARSVGGAEAPALEPPSAACLDLQASPSPSAPEAATCFSGFASAMSALAGGLGTFPGGLAGDFSFGRRPPTVATHAPQTLNPSPGFAPGHQTAAAGFRLSHLLYSREGTEV
What is the function of this protein?
Possible transcriptional activator.
What are the official names of this protein?
Forkhead box protein I2.
What are the subcellular locations of this protein?
Nucleus.
Protein: AK_SCHPO
Sequence: MSIAKNIENDPSKGWVVQKFGGTSVGKFPIKIAVDVAKEYLSTKRVALVCSARSTDTKAEGTTTRLIRATEAALRPAVGSVHDLVRIIETDHVQAARDFIQDVGIQDELIDAFHADCVELEQYLNAIRVLSEVSPRTRDLVIGMGERLSCRFMAAVLKDQGIDSEFIDMSHIIDEQREWRNLDASFYAYLASQLASKVTAVGNKVPVVTGFFGMVPGGLLSQIGRGYTDFCAALLAVGLNADELQIWKEVDGIFTADPRKVPTARLLPLITPEEAAELTYYGSEVIHPFTMSQVVHARIPIRIKNVGNPRGKGTVIFPDTISRHGSATPPHPPKIMPDDISASLANKGATAVTIKDTIMVINIQSNRKISAHGFLASIFAILDKYKLAVDLITTSEVHVSMALYEESDDGNMHEAFVELRRLGTLDILHGLAILSLVGKHMRNTTGYAGRMFCKLAEAQINIEMISQGASEINISCVIDEKMAVKALNVIHKELLEPLALHEVPSQASMLVEKPWLYSA
What are the official names of this protein?
Probable aspartokinase, Aspartate kinase.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: PTH_BRASB
Sequence: MLMFVGLGNPGAKYARNRHNIGFMAVDEISRRHGFSPWRRRFQGETSEGTLDSERVILLKPTTYMNESGRAVQEAAGFFKLGVGDVTVFQDELELPPGKLRVKVGGGIAGHNGLRSISAHLGNDYRRVRLGIGHPGVKELVHGHVLSDFAKSEMPWVEALCQAVADNAGLLTGKRDSTFANKVHLALQAKGFLDKGDAGAA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_CHLL2
Sequence: MDQTLSGFGNVFVFLALGIVFVAGGYLTARMLRPSRPNPEKNSTYECGEEAVGSAWVKFNIRFYVVALIFIIFDVEVVFLYPWATVFKQLGEFALFEALVFAGILILGLAYAWVKGDLDWVRPTPNIPKMPELPAGKPDGSRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATRIP_HUMAN
Sequence: MAGTSAPGSKRRSEPPAPRPGPPPGTGHPPSKRARGFSAAAAPDPDDPFGAHGDFTADDLEELDTLASQALSQCPAAARDVSSDHKVHRLLDGMSKNPSGKNRETVPIKDNFELEVLQAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPSVSHVSPRKNPSVVIKPEACSPQFGKTSFPTKESFSANMSLPHPCQTESGYKPLVGREDSKPHSLRGDSIKQEEAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFGSTLAGMSGLRTTGSYDGSFSLSALREAQNLAFTGLNLVARNECSRDGDPAEGGRRAFPLCQLPGAVHFLPLVQFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVSSGVETNPEDSVCILEGFSVTALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQVLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVVWLLAKLGVQSPLPPVTGSNCQCNVEVVRALTVMLHRQWLTVRRAGGPPRTDQQRRTVRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSMLIRGLPDVTDCEEAALDDLCAAETDVEDPEVECG
What is the function of this protein?
Required for checkpoint signaling after DNA damage.  Required for ATR expression, possibly by stabilizing the protein.
What are the official names of this protein?
ATR-interacting protein, ATM and Rad3-related-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the ATRIP family.
What are the subcellular locations of this protein?
Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage.
Protein: AP3A_SARS2
Sequence: MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLEAPFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPYNSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQLSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL
What is the function of this protein?
Plays a role in viral egress via lysosomal trafficking (PubMed:33157038, PubMed:33422265).  Forms homotetrameric ion channels (viroporins) localized at endosomes and lysosomes, that may induce deacidification of lysosomes, allowing safe egress of virions via lysosomal trafficking (PubMed:33157038, PubMed:33422265, PubMed:34158638).  Also blocks autolysosome formation by binding and sequestering the host component VPS39 for homotypic fusion and protein sorting (HOPS) on late endosomes (PubMed:33422265).  This prevents fusion of autophagosomes with lysosomes, disrupting autophagy and facilitating virus egress (PubMed:33422265).  Induces host RETREG1/FAM134B-dependent reticulophagy by interacting with host HMGB1 and enhancing the association between HMGB1 and host BECN1 (PubMed:35239449).  This induces endoplasmic reticulum stress and inflammatory responses and facilitates viral infection (PubMed:35239449).
What are the official names of this protein?
ORF3a protein, ORF3a, Accessory protein 3a, Protein 3a, Protein U274, Protein X1.
What are the subcellular locations of this protein?
Virion. Host cell membrane; Multi-pass membrane protein. Secreted. Host cytoplasm. Host endosome. Host lysosome. Note=The cell surface expressed protein can undergo endocytosis. The protein is secreted in association with membranous structures.
Protein: RL23_MACCJ
Sequence: MENRDIIKRPVITERSSEQMAQDKYTFDVDTRANKTQIKIAIEDIFNVKVDKVNVMNYKAKKKRVGRYNGYTNKRRKAIVTLKEGSIDFFN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL6_CHLAB
Sequence: MSRKARDPIVLPQGVEVSIQNNEILVKGPKGSLKQVLAPEVVIDIKGREVFVHPAPYVVDRPSRMQGLFWALISNMVQGVSVGFEKRLEMIGVGFRASVQGSILDLSIGVSHPTKIPIPADIQVSVEKNTIISVKGINKQLVGEFAANIRAKRKPEPYKGKGIRYENEYVRRKAGKAAKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MSD1_AMAEX
Sequence: MSDINATRLPIFWFIYFPCVSDVDSTLTRGER
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24050899).
What are the official names of this protein?
MSDIN-like toxin proprotein 1.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: CHIT1_HUMAN
Sequence: MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTWN
What is the function of this protein?
Degrades chitin, chitotriose and chitobiose.  May participate in the defense against nematodes and other pathogens.  Isoform 3 has no enzymatic activity.
What are the official names of this protein?
Chitotriosidase-1, Chitinase-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted. Lysosome. Note=A small proportion is lysosomal.
Protein: NAC59_ARATH
Sequence: MDYKVSRSGEIVEGEVEDSEKIDLPPGFRFHPTDEELITHYLRPKVVNSFFSAIAIGEVDLNKVEPWDLPWKAKLGEKEWYFFCVRDRKYPTGLRTNRATKAGYWKATGKDKEIFKGKSLVGMKKTLVFYKGRAPKGVKTNWVMHEYRLEGKFAIDNLSKTAKNECVISRVFHTRTDGTKEHMSVGLPPLMDSSPYLKSRGQDSLAGTTLGGLLSHVTYFSDQTTDDKSLVADFKTTMFGSGSTNFLPNIGSLLDFDPLFLQNNSSVLKMLLDNEETQFKKNLHNSGSSESELTASSWQGHNSYGSTGPVNLDCVWKF
What is the function of this protein?
Transcription activator that binds to DNA in promoters of target genes on a specific bipartite motif 5'-[AG]CGT[AG](4-5n)[AG][CT]ACGCAA-3' (PubMed:16359384, PubMed:21303842).  Triggers the expression of senescence-associated genes during age-, salt- and dark-induced senescence through a regulatory network that may involve cross-talk with salt- and H(2)O(2)-dependent signaling pathways (PubMed:21303842).
What are the official names of this protein?
NAC domain-containing protein 59, ANAC059, AtNAC3, Protein ORE1 SISTER1.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBC2_MEDSA
Sequence: MSTPARKRLMRDFKRLQHDPPAGISGAPQDNNIMLWNAVIFGPDDTPWDGGTFKLSLQFSEDYPNKPPTVRFVSRMFHPNIYADGSICLDILQNQWSPIYDVAAILTSIQSLLCDPNPNSPANSEAARMFSENKREYNRRVREVVEQSWTAD
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 2, E2 ubiquitin-conjugating enzyme 2, Ubiquitin carrier protein 2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: Y080_RICTY
Sequence: MLKKIIFGIIIPLLSTGCFANSTTSNFSKKDVAKTNDVSTQKIIDDFSAYAGTIKPEVREEIQKYRVEIVDINKKKRELYNKLSKEAQNFLAEQQKYKQKLSIPKLLTENHPNNNANANANSKDNNDKDME
What are the official names of this protein?
Uncharacterized lipoprotein RT0080.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: COA1_TTV1K
Sequence: MIIIKTKNREYTIDENKEINSISAADTICPYRAYRSYHRKIPIKIDDCKEARKIAGSMTHYVILRQLKEQGCETEKIVDPELKFRADAICDGDALLRLRQTSIGTGMRLISGN
What are the official names of this protein?
Coat protein TP1.
What are the subcellular locations of this protein?
Virion.
Protein: CLB10_ANOGA
Sequence: MAKVVDCVLLLAFIAVVRGQEACRTPDHRDGVCHPVQQCPSVRDEFFNSDRVLSEDEIDYLRKLQCKTKDVTICCPDGVTTVDRNPTAVRDGLPNPKAFECGLDTLADRIIGGNYTAIDEFPWYALLEYQSKKGERAFKCGGSLINGRYVLTAAHCLANKKLDEGERLVNVRLGEYNTATDTDCADGNPDDCADPPQNFGIEAQIVHPGYDKNGPYQHHDIALIRLDRDVTMNNFVSPVCLPPDDFPPTSPGLNVTAVGFGHTGRQRHSGIKKKAQFPVFAQEECDKKWKNIEVIGEQLCAGGVFGIDSCSGDSGGPLMVKRFYWIQEGVISFGNQCALEGWPGVYTRVSSYLDWIRQNIRR
What is the function of this protein?
Serine protease which preferentially cleaves after arginine residues (PubMed:33520733).  Involved in the innate immune response against parasite P. bergei infection by activating the melanization cascade (PubMed:33520733).  Probably in the hemolymph, cleaves and activates prophenoloxidase (PPO), which functions in the formation of pigments such as melanin and other polyphenolic compounds (PubMed:33520733).  In the susceptible strain G3, appears to be dispensable for ookinete elimination which occurs by lysis (PubMed:33520733).
What are the official names of this protein?
CLIP domain-containing serine protease B10.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IF1_PARUW
Sequence: MAKEDTIKIEGSVEELLPNMHFRVSLQNGLNVIAHLCGKMRMKNIRVLVGDVVTVEMSPYDLSKARIIFRQR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_NICRU
Sequence: MRIDPTTSGSGVSTLEKKNPGRVVQIIGPVLDVAFPPGKMPNIYNALVVQGRDSVGQPINVACEVQQLLGNNRVRAVAMSATEGLTRGMEVIDTGAPISVPVGGATLGRIFNVLGAAVDNLGPVDTSTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEENIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLLVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMKLEMESNLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL32_BUCAT
Sequence: MAVQKNKPTRSKRGMRRSHDSLTAPHLSIDKFSGETHIRHHITNNGYYKGKKVI
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SARAF_RAT
Sequence: MAVAAVGRPRAVRCLLLLLLSFLLVAGPALCWKNPDRILLRDVEALTLYSDRYTTSRRLDPIPQLKCVGGTAGCDAYTPKVVQCQNKGWDGYDVQWECKTDLDIAYKFGKTVVSCEGYDSSEDQYILRGSCGLEYNLDYTELGLSKLKESGKHQSFSDYYHKLSSVDSCGLVTVAVLFVLAFVVYKLFLSDGQGSPPPYSEHPPYSQHSQRFAGTAGAPPPGFKSDFTGPQSTSYGASSGFGSAFGGQSYASSGPGFWSGLGAGGLLGYLFGSNRAATPFSGSWYHPSYPSSYAGAWNSHAYSPLGGGAGRYSASSNTESRTRTTSGYGGTRRR
What is the function of this protein?
Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling.  In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions (By similarity).
What are the official names of this protein?
Store-operated calcium entry-associated regulatory factor, SARAF, SOCE-associated regulatory factor, Transmembrane protein 66.
What is the protein family that this protein belongs to?
Belongs to the SARAF family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Translocates to the endoplasmic reticulum-plasma membrane (ER-PM) region in a STIM1- dependent manner following cytosolic Ca(2+) elevation.
Protein: METK_BURM7
Sequence: MANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTTANIDYIQIARDTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQGAGDQGLMFGYACDETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGKPHSIDTVVLSTQHAPEIDLPALREAVIEEVIKPTLPADLIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALIQVSYAIGVAEPTSVMVNTFGTGRVSDETITKLVREHFDLRPKGIIQMLDLLRPIYEKTAAYGHFGREEPEFSWEAADKALALAEAAGVEPAVQVA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA3_MYCBO
Sequence: MTRVFHPALSGPEQSRYQITDVASVSRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVGVDKIRLTGGEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIEAVAAAGFTDTKLDSVVIRGFNDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPKYDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRAGASANDVVQILQRGWRDRANRGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase 3, Molybdenum cofactor biosynthesis protein A 3.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: PCNA_THEVO
Sequence: MIRMNISVRNLKEITDLLSTIVSEAKFKVDENGMSVTAVDPAHVAMIRLEVPKEVFSEFRSDGTEEIALDIDRLKSVIRLANSSENVGITKDKEKLKFDLGNISKSVSLLDPSTIVTPKIPNIASEYYAIIKRSDFERGLRAAEDISDSIRFVLSSEGFRATSHSESEESEMVLPKDMLSDLSCSDTIKSSYPLEYLLKFIKAVSSADSLKISFRDDYPLSIEFYLDQNPSAKIKGLFLLAPRMEQ
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: ATP6_VIBPA
Sequence: MAAPGEALTSSGYIAHHLSNLSLYKLGLVGSETSFWNVHIDSLFFSWFTGLIFLGIFYKVAKRTTAGVPGKLQCAVEMIVEFVADNVKDTFHGRNPLIAPLALTIFCWVFLMNVMDLVPIDFLPYPAEHWLGIPYLKVVPSADVNITMAMALGVFALMIYYSIKVKGLGGFAKELALHPFNHPLMIPFNLLIEVVSLLAKPLSLGMRLFGNMFAGEVVFILCAAMLPWYLQWMGSLPWAIFHILVITIQAFVFMMLTIVYLSMAHEDSDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GST_COCIM
Sequence: MTTPNFELYGYFRSSCSGRLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVSNINNTVSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIACDVQPVTNLKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAVWAAERVGMDLARFPITKRVFEEMLKEEAVQKAHWQKQEDTPEDLRA
What is the function of this protein?
Probable glutathione S-transferase.
What are the official names of this protein?
Probable glutathione S-transferase.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Zeta family.
Protein: HOA_CHLAD
Sequence: MKAPRLTDTTLRDGSHPMRHQFTREQVAKIVQALDRAGVPVIEVSHGDGLAGSSLQYGFSHTSEFDLIETARSYAERAKIAALMLPGIGTRQELKEAVARGIQVVRIATQCTEADISEQHFGLAKELGLETVGFLMMAHMRPPEALVEQAKLMESYGADCVYIVDSAGAMLPHDAAARVRALKEALSVQVGFHAHNNLGLGIGNTLAALEAGADQIDGCLRGLGAGAGNAATELLAAVLDRLGLNPGLDVFGLMDAAEYIVAPIMPFQPFPDRDAITIGYAGVYSTFLLHAKRAGEQYGIDPREILVELGRRQAVAGQEDWIIDVALDLSRRRGAGTRKEAHG
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: FMT_RICPU
Sequence: MKVIFMGTPEFAVPALKKLITHHEVKAVFTQQPKAKGRGLNLAKSPIHQLAFEHQIPVYTPSTLRNDEIINLINKVNADIIVVIAYGFIVPKAILEAKKYGCLNIHPSDLPRHRGAAPLQRTIIEGDRKSSVCIMRMDTGLDTGDILMKEDFDLEERITLEELHNKCANLGAELLIKTLANIDNIVPITQPSDGVTYAHKLTKAEGKINWHESAYKIDCKIRGMNPWPGVYFSYNDKIIKILEAEYLNADHHFTSGTVISDKLEIACGSGILRVKKLQQESKKALNIEEFLRGTNILKDTVLK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RL17_MYCSS
Sequence: MPKPTKGPRLGGSSSHQKALLANLATSLFEHGRIKTTEPKARALRPYAEKLITHAKKGELHNRREVMKKIRDKDVVHTLFAEIGPFFADREGGYTRIIKVEPRKGDNAPMAVIELVREKTVTSEANRARRVGASKQTAPVAAAAAPQAAVEPEATEGPDADDSSALPEAEDTTASEASRSTETDDPTQDSDADKS
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.