PharMolix/UniProtQA huggingface dataset:
Protein: QUEC_BACHK
Sequence: MKKEKAVVVFSGGQDSTTCLFWAIEQFAEVEAVTFNYNQRHKLEIDCAAEIAKELGIKHTVLDMSLLNQLAPNALTRTDMEITHEEGELPSTFVDGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMWIDKAETWKLSDELGAFEFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGASN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: COQ4_TRYB2
Sequence: MQSRVVSSAVMFLGGIAGAVKSLPAFVTSSFGAIVDPEDGRGSAAFAEITALTALHHMQRLMMADEMGRSILKERPQVTDETLEFAKTQPEGTFGYRYAAFMKRNNFLPSGRAPILHVSDPTLAYVMLRYRQIHDFVHAYVGLGRTIEEELAVKLFEWQHTGLPVGLMAVLGGMPWLRMDQILNMGMYNEWARANAPRQLHGKRFVSCILNVPWEWYLDKPYEQLVDDVGIVPLDAFLKERKSGGLHDS
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: STEC_SALT1
Sequence: MPFTFQIGNHSCQISERYLRDIIDNKREHVFSTCEKFIDFFRNIFTRRSLISDYREIYNLLCQKKEHPDIKGPFSPGPFSKRDEDCTRWRPLLGYIKLIDASRPETIDKYTVEVLAHQENMLLLQMFYDGVLVTETECSERCVDFLKETMFNYNNGEITLAALGNDNLPPSEAGSNGIYEAFEQRLIDFLTTPATASGYESGAIDQTDASQPAAIEAFINSPEFQKNIRMRDIEKNKIGSGSYGTVYRLHDDFVVKIPVNERGIKVDVNSPEHRNCHPDRVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQESRQQRSVSLATRQLEEQIKAHHMIKLKRAETEGNTEDVEYYKSLITDLDALIGEEEQTPAPGRRFKLAAPEEGTLVAKVLKDELKK
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is a kinase, which is required for SPI-2 TTSS-dependent F-actin meshwork formation in infected host cells (By similarity).
What are the official names of this protein?
Secreted effector kinase SteC, Salmonella translocated effector C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm.
Protein: BTUF_VIBPA
Sequence: MMNKICLYLPLFFSSLTMANEPVERVISLAPHATEIAYAAGLGDKLIAVSEMSDYPKEAGELEKVSNYQGIKLERIIALQPDLVIAWPAGNPAKELEKLKQFGVPIYYSTTGTLEDIANNIEQLSQYSDDPSKGQKAARDFREELTALKAKYNTTEKVRYFYQLSEKPIITVAGKNWPSEVFNFCGGENVFANTAAPYPQVSIEQVITRQPEVLFTSRHAMSDDGMWAQWKNELPALRNNHVWSLNSDWINRPTPRTLNAIIEVCEHFESVKRKR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LPXB_BURPS
Sequence: MAFQLTPLRVALVAGEPSGDLLGASLLGGLHARLPASSRYYGIGGPRMSAVEFDAHWPMEKLAVRGYVEALKHIPEILRIRGELKRQLLAEPPDAFVGIDAPDFNFGLEQALRGAGIPTIHFVCPSIWAWRGGRIKKIVKAVDHMLCLFPFEPELLEKAGVAATFVGHPLADEIPLEPDTHGARIALGLPDGGPVIAVLPGSRRSEIELIGPTFFDAMELMQQREPGVRFVVPAATPVLRALLQPLVDAHPSLSVTLTEGRAQVAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILAGRFVVPELLQHFATPDALADATLTQLRDDANRRALTDIFTDMHLALRQNTAQRAAEAVARVIDSRKPR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: PSA6_ENCCU
Sequence: MGSQARYNMFKIFNPEGCVKQLDFIRQTTELGGTAVGLKNRSVGVLIAHNERRSRLADIQKKVFSIDRKSLFTFSGITNDGLQIVDYLIDKSVREEVIKGRAIHFLDVFEDLLRDVFERTILDGRRLYGVSGLYMTEYDGIRLVEFNPKGHVREVKGMGIGCRAQSSRTVLEAYCEEYEKMGVEELVRIGIMALKNAHPEDDALTGENVEIWILEAGKAVYNIDAKVFLN
What is the function of this protein?
The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit alpha type-6, 26S proteasome alpha-type subunit PRE5, Multicatalytic endopeptidase complex subunit PRE5.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MECR2_CAEEL
Sequence: MQKTIRSQALIYRKFGDPLKVLQLETVEVPAEPGSGECLVEWLASPINPLDINRIQGNYAVRAELPVIGGSEGVGRVVKAGSGSRFKSGDHVTIFSANTPIWTEFGVVDDDELVKLDNRIPLDLAATLMINPPTAWIMLKKYVNLQKGDYIIQNSANSGVGRSVIEMCKALGYKSINIVRNRQNIEALKTDLWRIGADHVFTEEEFKGTSRQFLKSINVRPKLALNGVGGKSALQISSVLERGGTCVTYGGMSKKAHEFTTSALVFNDICVRGVAVGMWARQEEHLDEWNLCVDEVQKLAVAGKITAIPMEKVVLADHKTAIQKSLEGRSIKQLFVINSKASASHI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II).  Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase, mitochondrial, 2-enoyl thioester reductase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: AROQ_XANC5
Sequence: MAHLLLLHGPNLNLLGTREPEVYGRTTLAQIDAALVDRAQAAGHVLHCLQSNAEHVLVERIHAAREDGTAYILINPAAFTHTSVALRDALLGVGLPFVEIHLSNPHAREPFRHHSYLSDKADGVICGFGADSYRLALEAVIARLERDA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: TRKA_METTH
Sequence: MYVVIMGGGRVGLTLANLLISDGHDVTLIENEETLCANAAVELDALVICGNGTDIKTLEEANISNADVFVAATGNDEANLLSCILVREYSIPKIIARVSNPDHEEAFKKVGIDHVISPERTAAGYLEKLITRPKVADLIVLGHGDAEILDMEIRSSKVVGKRVGDVSPTDKYIIVAIYNNGDLIIPQPDMVLERGTKVSVLVKTDAVKEATRRFTG
What is the function of this protein?
Part of a potassium transport system.
What are the official names of this protein?
Trk system potassium uptake protein TrkA homolog, K(+)-uptake protein TrkA homolog.
Protein: ACP_ECO24
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVP2_ARATH
Sequence: MMMDEDVEQASLMSFNDRPRAFPNMRSKTYSPLIFRIIRKLNVRVLSIILLFCFGAIFYMGASTSPIIVFVFTVCIISFLLSIYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTISKMAILLAFVILCIYLFRSLTPQQEAAGLGRAMSAYITVAAFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFYVWLGVGSPGSMNVTDLPLLLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIISAMILGGTMAKKCKIEDPSGFILFPLVVHSFDLIISSIGILSIKGTRDASVKSPVEDPMAVLQKGYSLTIILAVITFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGVSLGLESTALPVLTISVAIISAYWLGNTSGLVDENGIPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKEVDIAIPEVFVGGLLGAMLIFLFSAWACAAVGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLVFRILGYYTGQPLLGAKVVASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLVMAPVFL
What is the function of this protein?
Pyrophosphatase active in both inorganic pyrophosphate hydrolysis and H(+) translocation.
What are the official names of this protein?
Pyrophosphate-energized membrane proton pump 2, AVP1-like protein 1, Pyrophosphate-energized inorganic pyrophosphatase 2, H(+)-PPase 2, Vacuolar proton pyrophosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PCNA_DROME
Sequence: MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKFRCDRNLSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMNLDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANIKLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYAIKDLGHIRYYLAPKIEDNET
What is the function of this protein?
Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility.
What are the official names of this protein?
Proliferating cell nuclear antigen, PCNA, Cyclin, Mutagen-sensitive 209 protein.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Colocalizes with crm in polytene nuclei during embryogenesis (PubMed:9310333). Increased association with chromatin in response to DNA damage caused by methyl methanesulfonate (MMS), hydrogen peroxide (H2O2) and UV (PubMed:17087725).
Protein: YORV_BACSU
Sequence: MDSYPESLKKETEEIKERVRNGNIKEDKIKEIAETTVEFLKSEEKRHKYFSEVAAAMADNLSEFFKSYLKGE
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YorV.
Protein: TIG_SHESH
Sequence: MQVSVETTQGLERRLTISVPAEQIEKAVTDSLKNEAKRARIPGFRPGKVPVSVINKRYGKAIRQDITGEVMQRNFIEAIIAEKLNPAGAPTFVAGDTDTENFNFVATFEIYPEVELTGLDAITVEQPTSEVTDADVDTMIETLRKQHATFEAVERESVVGDKAKINFVGSIDGEEFEGGKAEDFELELGSGRMIPGFESGVEGHKAGEEFDIEVTFPEDYHAENLKGKVANFVITLNEVLAANLPEVNDEFAKLFGVTDGGLEALKAEIRKNMGRELEQALKANVKEQVLNGLLEQNNIELPKPLIDGEVEVLRKQAMQRFGDQAANMPELPADLFTEQAERRVKVGLLLGEVIKTNELKAEDDRVQSLIASMASAYEDPSEVVAYYNGNEEMLQNMRNVALEEQAVEALLKTAKLTEKAVNFEEFMNKATQQG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: SYP_MICLC
Sequence: MPLRMSTLFLRTLRDDPAEAEVASHRLLVRAGYIRRAAPGIYSWLPLGLKVLAKVERIVREEMDAIGAQEVHFPALLPREPYEATGRWDEYGDGLFRLQDRRGNDYLLAPTHEEMFTLLVKDLYSSYKDLPAYLYQIQTKYRDEARPRAGLLRGREFIMKDSYSFTVDDAGLDAAYEAHRAAYLRIFDRLGLEVVPVRATSGAMGGSRSEEFLHPTEVGEDTFVESDGGYRANVEAVTTVAPAPLDEAAMAALPAAEVKDTPVSTTIAALVDVANQLAPREGEPWTAADTLKCVVVTAVVDGGERRPFVVGVPGDREVDLKRLEASVGSALGVVGEPTLEAATAADLAEHPALVKGYIGPAAVDAVEGTPVLGADDSVSGLPFFVDPRIAPGTAWITGANADQRHVFGLVAGRDFTWDGVLEATAVREGDEAPDGSGPLHTRRGMEMGHIFQLGRKYAEALDLKVLDVHGKQVVVTMGSYGIGITRAVAAIAERYHDDKGLAWPRAVAPADVHVVVATKGEDGLAAAETLAASLEAEGLTVLVDDRPKVSPGVKFKDAELIGVPTTVVIGRGLADGELELKDRATGEARPVPVDGAVAAVLAEVRDGR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBR4_YEAST
Sequence: MDMVSPVLNLQSSILGELVGIIGKVFFLLIEEIKYPIITPKIIVDAQISSWSLFFFASICNLSAKFREPIVTTSSIISLMESEKDLKNVNEYFQIMAKMLFILENKIVVSLFVVFNISVLIIVKSEPYSYGKVLFKPSSSIF
What are the official names of this protein?
Putative uncharacterized membrane protein YBR064W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOC_CLOK5
Sequence: MFELNNFDALQIGLASTEKIREWSRGEVKKPETINYRTLKPERDGLFCERIFGPQKDWECHCGKYKRIRYKGIVCDRCGVEVTKAKVRRERMGHIELAAPVSHIWYFKGIPSRMGLILDMSPRALEKVLYFASYVVLDPKETQLLKKQLLTEKEYREAVDKYGEQNFVASMGAESVKKLLEEIDLEQLSLVLKEDLKNSTGQKKIRIIRRLEVVESFRKSGNRPEWMVIDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKKLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKMYQCGLPKEMALELFKPFVMKKLVERGLAHNIKSAKRMVERVQAQVWDVLEEVISDHPVLLNRAPTLHRLGIQAFQPVLVEGRAIKLHPLSCTAYNADFDGDQMAVHVPLSVEAQSEARFLMLAAHNILKPSDGKPVVVPTQDMVLGSYYLTVEREGAKGEGRYFSFPDEVIMAYQLKQIDINAKIKVKMTKIIDGKYISGIIDATAGKIIFNECVPQDLGFIDRSKPGNEFKLEIDFLVAKKNLGKIINKCYMKHGATKTSIMLDKIKARGYHYSTISGITVSTSDMEVPEAKKRLLSESDAAVDKIEKMYRRGFISEDERYQRVIERWTKTTEDVADELMNNLDKFNPIFMMADSGARGSKSQIKQLAGMRGLMANPSGKIIELPIRASFREGLDVLEYFISTHGARKGNADTALKTADSGYLTRRLVDVSQDVIVREEDCGTYEGYDVSEIKEGNEVIESLSERLTGRYSAEDIIDPNNHQIIVPKNSYMDSKLADRIEASGIKKVKIRSVFTCKSRHGVCSKCYGMNMATAQKIDIGESVGIIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRVEELFEARKPKGLAIVSEVSGTVKMEETKKKRSVSVITDNGEEVTYDIPFGSRIKVSNGDLISAGDEVTEGSVNPHDILRIKGVQGVKNYLLSEVQKVYRLQGVDINDKHLEVVIRQMTRKIKIEESGDTELLPGTMIDIFDFEEENARVEASGGSAAQGRVALLGITKAALATESFLSAASFQETTRVLTDAAIKGKIDPLLGLKENVIIGKLIPAGTGMTRYRSIKINTENEVQENQLEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL25_LISMF
Sequence: MATTLEVQKRETTQHSEVTRLRSEGKVPGIIYGYKSENVPVSVDSLELIKAVRDNGRNAVFSVTVDGKKLNVLLHEYQVDPLKDVLVHVDLLAVDMNEEVETDVRVVLVGDAPGVKAGGVLQQIIHDVKVSATPEKLPETIELDISSLEIGDVLTTNDLPENKDYVVQAEEEETVVTVSAPRAEEEPTTTEAPEPEAVHGKDEEPVE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ARF1_PLAFA
Sequence: MGLYVSRLFNRLFQKKDVRILMVGLDAAGKTTILYKVKLGEVVTTIPTIGFNVETVEFRNISFTVWDVGGQDKIRPLWRHYYSNTDGLIFVVDSNDRERIDDAREELHRMINEEELKDAIILVFANKQDLPNAMSAAEVTEKLHLNTIRERNWFIQSTCATRGDGLYEGFDWLTTHLNNAK
What is the function of this protein?
Small GTPase involved in protein trafficking between different compartments (By similarity).  Modulates vesicle budding and uncoating within the Golgi complex.  In its GTP-bound form, triggers the recruitment of coatomer proteins to the Golgi membrane.  The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles (By similarity).  Regulates the transport of N-acylated AK2 to the parasitophorous vacuole membrane.  May be involved in the activation of lipid kinase PIP5K (By similarity).
What are the official names of this protein?
ADP-ribosylation factor 1, plARF.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: RISB_MYCVP
Sequence: MSPAAGVPELPALDGKGLRLAIVASTWHETICDALLDGARKVAVGAGIDDPTVVRVLGAIEIPVVAQALARTHDAVVALGVVIRGETPHFDYVCDAVTQGLTRVSLDASTPVANGVLTTNTEHQALDRAGLPDSAEDKGAQAAAAALSTALTLRQLS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ARBH_DICCH
Sequence: MKIKNSYLVIASLLYPISFISTAASLTVEQRLAALENDLQETKQELQRYKEQEKKNKAITLVRVNSAADADNKSNAFNVAKTATPIA
What is the function of this protein?
May be a sugar porin with a broad carbohydrate specificity.
What are the official names of this protein?
Putative outer membrane protein ArbH.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: EFNMT_BOVIN
Sequence: MNLLPKSSKEFGSVDYWEKFFQQRGKKAFEWYGTYLELCGVLHKYIKPREKVLVVGCGNSELSEQLYDVGYQDIVNIDISEVVIKQMKERNASRRPRMSFLKMDMTQMEFPDASFQVVLDKGTLDAVLTDEEEKTLQQVDRMLAEVGRVLQVGGRYLCISLAQAHVLKKAVGHFSREGWMVRVHQVASSQDQLLEAEPRFSLPVFAFIMTKFRPVTGSALQIFELCAQEQGKPVRLESAEQLAEAVRERQQYAWLCSQLYRKAGLGSVSLDLCNGDTGEPRYTLHVVDSPTVKPSRDNHFAIFIIPQGRETEWLFGMEEGRKQLAASAGFRRLITVALHRGQQYEGMDSIQAELSARVMELAPAGMPAQLQVPFLSVGGDIGVRIVQHQACSPLSGDYVIEDVQGDDKRYFRRLIFLSNRNVVQSEARLLQDVSHRAQKKRKKDRKKHRPADTPEDLPAAQGQSIDKSYLCCEHHKAMIAGLALLKNPELLLETPLALLVVGLGGGSLPLFIHDHFPKSCIHAVEIDPSMLEVATQWFGFSQSDRMKVHIADGLDFITRLAEEEARPHYDVIMFDVDSKDPTLGMSCPPPAFVAQLFLQKVKSILTPEGVFILNLVCRDLGLKDSVLAGLKAVFPLLYVRRIEGEVNEILFCQLHSECKLATPELLEMARALEQTLRKPGKGWDDTYVLSDMLNTVKIV
What is the function of this protein?
Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation (By similarity).  Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2' (By similarity).  Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55' (By similarity).  Has no activity towards core histones H2A, H2B, H3 and H4 (By similarity).  Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6 (By similarity).
What are the official names of this protein?
eEF1A lysine and N-terminal methyltransferase, eEF1A-KNMT, Methyltransferase-like protein 13.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: CAID_ECO57
Sequence: MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEESYSYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR
What is the function of this protein?
Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
What are the official names of this protein?
Carnitinyl-CoA dehydratase, Crotonobetainyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: YAG6_YEAST
Sequence: MLSLVKRSILHSIPITRHILPIQLILVKMNHVQIRNIKLYHFISYGFMLTKLTVFLFNLFFYRLRILCRLTLLILSLPVQIYIKEIQTKMLEKHTASDTSCI
What are the official names of this protein?
Putative uncharacterized protein YAL066W.
Protein: RL20_HELPS
Sequence: MRVKTGVVRRRRHKKVLKLARGFYSGRRKHFRKAKEQLERSMYYAFRDRKQKKREFRSLWVVRINAACRMHNTSYSRFMHALKVAGVELDRKVLADMAMNDMQAFESVLESVKEHL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: COMB_CALS8
Sequence: MKIITFSHYKEVTDDVLKDSYAVVIDLLRATSTMIWAISNGAKGIIPVEDISEARLLKRLDESVLLGGERGGLKIEGFDLDNSPLSYKKEAIFGKTVVMTTTNGTRALKKASCAKRIFLGSFINAKKTAEYIMKETLHYNIDTISIVCAGTEEKFTLEDILCAGYFVDLFIENFPDVFLDDLSLASHVLYKKFENDPHEILKYSYHYNHLKKLGFEADLEFCLRKDFVDCVCEFRNLVVEKV
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: LPXD_PASMU
Sequence: MQVYSLQELAQQIGATIRGNADVVVESIAPLDKATEKQLTFISNPKFRSLLAQSHAGILVVSEADVAFCAEQSNLLIVKDPYVAYAVLAQYMDSTPKAASGIAASAVVSASAVIGKNVSIGANAVIEDGVTLGDHVVIGANCFVGKNSKIGAYTQLWANVSVYHEVEIGQHCLIQSGAVIGSDGFGYANDRGRWIKIPQVGQVIIGNHVEIGACTCIDRGALDPTVIEDNVIIDNLCQIAHNVHIGTGTAVAGGVIMAGSLTVGRYCLIGGASVINGHMEICDKVTITGMGMVMRPITEPGVYSSGIPLQTNKEWRKTAALTLGIDAMNKRLKALEKKFEKK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RBM7_BOVIN
Sequence: MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHEVSVPYAMNLLNGIKLFGRPIKIQFRAGSSHASQEVSLSYPQHHVGNSSPTSTSPSRTVDNMTPSAQTIQRSFSSSENFQRQAVMNNVLRQMSYGGKFGSPHLDQSGFSPSAQSHNHTFNQSSSSQWRQDTPSSQRKVRLNSHPYVMDRHYSREQRYSDLSDHHYRGNRDDFFYEDRNHDGWSHDYDNRRDSGRNGKWRSSRH
What is the function of this protein?
RNA-binding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation.  NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs.  Binds preferentially polyuridine sequences and associates with newly synthesized RNAs, including pre-mRNAs and short-lived exosome substrates such as promoter upstream transcripts (PROMPTs), enhancer RNAs (eRNAs), and 3'-extended products from small nuclear RNAs (snRNAs).  Participates in several biological processes including DNA damage response (DDR) and stress response.  During stress response, activation of the p38MAPK-MK2 pathway decreases RBM7-RNA-binding and subsequently the RNA exosome degradation activities, thereby modulating the turnover of non-coding transcriptome.  Participates in DNA damage response (DDR), through its interaction with MEPCE and LARP7, the core subunits of 7SK snRNP complex, that release the positive transcription elongation factor b (P-TEFb) complex from the 7SK snRNP.  In turn, activation of P-TEFb complex induces the transcription of P-TEFb-dependent DDR genes to promote cell viability.
What are the official names of this protein?
RNA-binding protein 7, RNA-binding motif protein 7.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus. Note=Excluded from the nucleolus.