PharMolix/UniProtQA huggingface dataset:
Protein: COAE_HAEDU
Sequence: MAFVVGLTGGIASGKTTIANMFAELGATIIDADIVARQVVTKGSPLFLKIVQHFGQQVLTTQGELNRAQLRQLIFANQVEKNWLNNLLHPAIRREMLIQLRQARGPYVLFVVPLLIENKLIEFCQRVLVIDVYPEVQLARALTRDRSNIATIRGIMASQVNRLTRLSYANDIIENNLPLAESLERLQMQVQQLHQYYLTLATQQE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_ECO7I
Sequence: MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL15_LACP7
Sequence: MNLTDLRPADGSKQSGNFRRGRGHGSGNGKTAGKGHKGQKARSGAPRVGFEGGQMPLYRRLPKRGFKNRNTKEIISVNVSMLNRFEDGADVTLESLREIGIISNPKDGVKILGNGELTKKLNVKVSAFSESAIEKIKALGGNAEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PCRB_STAHJ
Sequence: MYDIKAWQHVFKLDPAKEISDNDLDALCMSDTDAIMIGGTDNVTEDNVIHLMSRVRRYPLPLVLEISNIESIIPGFDFYFVPTVLNSQDTTYHNGMMHKALKQFGFMVNFDEVVLEGYLVLNPDSKVAKLTQSNTNIDIEDVEAYAQMVNEMYKLPLMYLEYSGQYGDVEKVEAASRLLTNTQLFYGGGITSIEQAREMAQYADTIVVGNIIYDDIKKAIKTVKIKKESNK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: NQOR_METAC
Sequence: MVKVNIIFYSMYGHVYRMAEAVAAGAREVEGAEVGIYQVPETLPEEVLEKMGAIETKKLFAHIPVLTREMNEEVLAGADALIFGTPTRYGNMTAQMRAVLDGLGGLWNRDAFVGKVGSVFTSSGTQHGGQESTILTFHVTLLHLGMILVGLPYSEKRQTRMDEITGGSPYGVSTIAGGDGSRQPSENELAMARYQGRHVTLIAKKIAGK
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: CYB_KOGSI
Sequence: MTNIRKTHPLMKIINNAFVDLPTPSNISSWWNFGSLLGLCLITQILTGLFLAMHYTPDTTTAFSSVTHICRDVNYGWVIRYLHANGASMFFICLYAHVGRGLYYGSYVFQETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLMSAIPYIGTTLVEWVWGGFSVDKATLTRFFAFHFILPFIILALAMVHLLFLHETGSNNPLGIPSDMDKIPFHPYYTIKDILGALLLISALLTLTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVMALLLSILVLMLIPMLHTSKQRSMMFRPFSQFLFWVLVADLLTLTWIGGQPVEHPYMTLGQLASTLYFLLILVLMPLTSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNPA_VIBPA
Sequence: MNTYAFNRELRLLTPEHYQNVFQQAHRAGSPHFTIIARNNKLSHPRLGLAVPKKQIKTAVGRNRFKRLARESFRNSQHQLPNKDFVVIAKKSAQDLSNEEIFKLFDKLWQRLSRPSRG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: LUXS_BIFLD
Sequence: MAEETAEKPVVESFQLDHTKVKAPYVRYIDTETGPHGDVISNYDLRLTQPNKQAIPTGGLHTIEHTIAVLLRERIPGYIDCSPFGCRTGFHLLTWGTHPTEEVAKALKESLEFIAYKATWDDVPATTEKSCGNYRDHSLFTAKEWAKQILEEGISSDPFERKVV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: MSRA_MALP2
Sequence: MIKKIYLAGGCFWGIEQYYNLNQKIISTNVGYLNSKIDNPTYKDVCNNITDAVEAVELTYDDQVISLNEIIDLLFKVIDPTSINKQGNDIGRQYRTGIYSRDSNELMAIQEKINELQNNYSKLIQTEVMLVDNYYLAEEYHQKYLEKNPNGYCHINLKAK
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: WOX4_ARATH
Sequence: MKVHEFSNGFSSSWDQHDSTSSLSLSCKRLRPLAPKLSGSPPSPPSSSSGVTSATFDLKNFIRPDQTGPTKFEHKRDPPHQLETHPGGTRWNPTQEQIGILEMLYKGGMRTPNAQQIEHITLQLGKYGKIEGKNVFYWFQNHKARERQKQKRNNLISLSCQSSFTTTGVFNPSVTMKTRTSSSLDIMREPMVEKEELVEENEYKRTCRSWGFENLEIENRRNKNSSTMATTFNKIIDNVTLELFPLHPEGR
What is the function of this protein?
Promotes differentiation and/or maintenance of the vascular procambium, the initial cells of the developing vasculature (PubMed:20044450).  Part of the TDIF-TDR-WOX4 signaling pathway that plays a crucial role in the maintenance of the vascular meristem organization during secondary growth (PubMed:20729381).  Is required for promoting the proliferation of procambial/cambial stem cells but not for repressing their commitment to xylem differentiation in response to the TDIF signal (PubMed:20729381).  Acts redundantly with WOX14 downstream of the TDR/PXY receptor kinase to regulate procambial cell proliferation and differentiation in vascular tissue, independently of any role in vascular (PubMed:23578929).  Acts as a cambium regulator in the inflorescence stem (PubMed:21926336).  Is required for auxin-dependent cambium stimulation in the inflorescence stem (PubMed:21926336).
What are the official names of this protein?
WUSCHEL-related homeobox 4.
What is the protein family that this protein belongs to?
Belongs to the WUS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUA_BURL3
Sequence: MRIALGIQYDGAAFCGWQAQPHGKTVQDRLEHALAEFARVPLHTTVAGRTDTGVHGLGQVVHFDTDLDREVFSWVRGTNAFLPSTVAVQWAKPMPETFHARFSAFERTYYYALYVHPVRSPMLAGRAGWIHTPLDDDAMRAAAAHLIGEHDFSSFRSSECQSKTPVKHLYQIDVRRVGHFVHFRFRANAFLHHMVRNLMGCLVAVGRGRYPADWLADVLAGRDRNLAAPTFMADGLYLAHVGYPAEFAVPPAQLGSVPWSSVWADLDPQS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: SMG_LEPCP
Sequence: MFDVLVYLYENYWRPDACPDHDQLSKKLSAVGFESEEIADALTWLDGLAGAAESHIGTQSELSLRVYSPSEQDHLGLASIAFISFLESAGVLPPAMREIAVDRAMALGGGPVALEDLKIIVLMVFWSLGEEPDALILDELFVDAEDRLIH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RS20_RHOP5
Sequence: MANTTSAKKATRKIARRTIVNKSRRTQMRGAVRTVEEAIAKGDRDAAVKAMTRCEPELMQAAQRNIIHRNAASRKVSRLTQKIAKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DNLJ_BRUSI
Sequence: MSDISVEKLTELEAAAELERLARAIAHHDELYHAKDRPEISDAAYDALKRRNEAIEAHFPALVRDDSPSRRVGAAPALATFAPVVHARPMLSLDNAFSDEDVRDFVGSVYRFLGQLPDDSIAFTAEPKIDGLSMSIRYENGILVSGATRGDGTTGENVTANIRTIAEIPNRLPAGAPAVVEVRGEVYMAKSDFLTLNAQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLRFFAYAWGEMSDMPADTQLGMVEVFRQWGFPVNPLMKRFNSVDGLLAHYRAIGMERPTLDYDIDGVVYKVDRLDLQTRLGFRSRSPRWAIAHKFPAEQALTILRGIDIQVGRTGALTPVARLEPITVGGVVVTNATLHNEDYIKGIGQKGEPIREGRDIRIGDSVIVQRAGDVIPQIVDVVLEEGKKRGEPYQFPHVCPACGSHAVREEGEAVRRCTGGLICPAQAVERIRHFVSRNAFDIEGLGEKQVEFFFNAEDPALCIRSPADIFTLKKRQENSLTKLQNIEGFGATSVKKLYDAIDARREIALHRFLFGLGIRHVGEVNAKRLARAYLSYAAFEKAALEAVPPKEGDRTDKGSEAWQDMLAVEGIGSIVAEAVVDFYGEPHNREVLAALLAEVTPLDEEARVATGSPVEGKTVVFTGSLERMSRDEAKAMAERHGAKTAGSVSKKTDLVVAGPGAGSKLAKATELGIEVINEDDWFKLVGED
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PRRC1_CHICK
Sequence: MMEESGIEATPPGTPPPSTAGSTAASATPVSLALSSPLATPSMSSPAYSPPLPAAVAPLPPPIMTSATPSFVPSAAVSTIAPPLAPAPAPVTSSAFSTSLPQFSAPPPLSSTSGSGLSVPPTGPPISGFSLSSTYDITRGHAGRAPQSPLMPSYSAPPVTGVLADPITQQAPFSSPLASGTGSGSSITFPEEHEDPRVSAAQSGAPTGGLWGFIKGVAENPMVKSVLDKTKHSVESMITTLDPGMVPYIKTGGELDIVVTSNKEVKVAAIRDAFQEVFGMAVVTGEAAQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQPAVSVESFIEELLPDKWFDIGCLIIEDPVHGIHLEAFTQATPVPLQYVQQAKSLTPQDYNLRWSGLLVTVGEVIEKNLLNISRTDWHAVFTGMSRRQMIYSTAKALAGMYKQHLPPRTV
What are the official names of this protein?
Protein PRRC1, Proline-rich and coiled-coil-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRRC1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: CH60_CAMRE
Sequence: MAKEIFFSDEARNRLYEGVRKLNDAVKVTMGPRGRNVLVQKSFGAPAITKDGVSVAKEIELKDALENMGAGLVKEVASKTNDEAGDGTTTATVLAHSIFKEGLRNITAGANPVEVKRGMDKQAAAIIAELKNLSRKVTDKKEIAQVATISANSDSAIGGLIADAMEKVGKDGVITVEEAKSIQDELNVVEGMQFDRGYLSPYFITNAEKMQVELQSPYILLFDKKITNLKDLLPVLEQIQKTGKPLLIIAEDIEGEALATLVVNKLRGVLNISAVKAPGFGDRRKAMLEDIAILTGGEVVSEELGRTLESATLSDLGQASSVIIDKDNTTIVNGAGEKSAIDARIIQIKAQIAETTSDYDKEKLQERLAKLSGGVAVIKVGAATETEMKEKKDRVDDALSATKAAVEEGIVIGGGAAFIKAGAKVDLNLSGDEAIGADIVRRALTAPLRQIAENAGFDAGVVANSVSVSKDDNYGFNAATGEYVDMFKAGIIDPVKVERIALQNAVSVASLLLTTEATISELKEDKPMPAMPDMSGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_AQUAE
Sequence: MPKNDLLLRSLRGEPIGRFPVWLMRQAGRYMPEYRKIRNRVKNFLELCKNVDLATEISLLPLKILGVDAIIIFSDILVPLEPLGVKVEFVEGEGPKLSWSGKVSDLKKYDPSQNAYVYEIIKRVKEAQDEVPVIGFAGAPFTLLSYLIEGGASKDFKSTKLFMWENPKEYKRLMDILTETVLAYLKEQIKAGADVVQIFDSWVNNLSLEDYGEYVYPYVNYLISELKDFSDTPVIYFFRGSSSFIDLAVDYRADALSVDWSVDIPELFKIYDKGFQGNLEPAVLYASEEVIEEKTLGLLRRIPVKTRYVFNLGHGLAPDMELEKVKYLVDLVKSFPLT
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX31B_SCODE
Sequence: MKSSMAVLLVMGLIIFTLDKCYSTDDKPIGKCGEKQRSKLCRVCHNRSGIDNYYSGCCIYDGTYFMCLDMLHP
What are the official names of this protein?
U-scoloptoxin(03)-Ssd1b, U-SLPTX(03)-Ssd1b, Toxin SSD1084.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-03 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CDPK3_PLABA
Sequence: MNQLCVERNLSISTAYIKSKPKKYIERIKKKKSSNKSIKSQHKFEGSKIANKNNELKDIKSKDPKHYENHINKNTKHKDILLKSKRSDNFKFSRRGFILSFTGNLEDFYNLSEEPLGKGTYGCVYKATDKLLKIQRAVKVVSKKKLKNIPRFRQEIDIMKNLDHPNVIKLLETFEDEEQIYLIMDLCTGGELFDKIIKKGSFVEMYASFIMKQIFSVLNYLHIRNICHRDIKPENFLFYDKSTESLIKIIDFGLAAYFNDIDYEMKTKAGTPYYVAPQVLTGCYDYKCDLWSAGVLFYIILCGYPPFYGESDHEILSMVKKGKYNFKGKEWNNISEEAKDLIKRCLTIDSGKRINASEALKHPWFKKKKGSFNLDVKMDIHVLENFKNYALLLKLQKLAMTIIAQQSNDYDLQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFLAAALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMMKLKY
What is the function of this protein?
Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase (By similarity).  In the mosquito midgut, regulates the gliding motility of the ookinete which is essential for the ookinete to invade the midgut epithelium (PubMed:16796674).  However, another study showed that while required for ookinete invasion of the midgut epithelium, is not required for ookinete gliding motility (PubMed:16430692).
What are the official names of this protein?
Calcium-dependent protein kinase 3, PbCDPK3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_AGRRK
Sequence: MTARKSLDRYRRIVIKIGSALLVDRKTGLKKAWLDGMCADIAALKAKGVDVLVVSSGAIALGRSVLDLPSGALKLEESQAAAAVGQISLARAWSESLSHDDIVAGQILLTLGDTEERRRYLNARATINQLLKIGAVPIINENDTVATSEIRYGDNDRLAARVATMTGADLLILLSDIDGLYTAPPHLDPDAKFLETIADITPEIEAMAGGAASELSRGGMRTKIDAGKIATGAGCAMIIASGKTDRPLNAIANGARSSWFAPSGTPVTARKTWIAGQLQPAGELHVDEGAVTALGAGKSLLPAGVRKVTGHFGRGDTIAVIGPSGREIARGLVGYDAEEARQITGRKSAEIEAILGYAGRAAMVHRDDLVMTASVKTKAEKLKKDEAHA
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTF_ECOL5
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQESLSNLFGGKTPMEHRFAAARWQTGVTGCPQLGEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: B2KBA_SICCD
Sequence: WIMGHMVNAIERVDEFLNLGANAIEFDIDFDKDGIAQITHHGIPCNCGRKCTKKAIFTEYLDNIRQVTTPDDPKFREQLVLLALDLKLLRISSAKAYRAGEDVAKKLLDHYWQRGNSRARAYILLNIPLVEDYEFIRAFKDTLKNEGYESYNDKVGINFTGNEDLDKIRDVLEILGIHKQVWQADGITSCFARGTERLKEALEKRDTPGYNYINKIYAWTLVRKSIMRRSLRLGVDGVMSNNPDRVIKVLKEKEFADKFRLATYNDNPWEKFRG
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SdSicTox-betaIIB1bx, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: INVO_HYLLA
Sequence: MSQQHTLPVTLSPALSQELLKTVPPPVNTQQEQMKQPTPLPPPCQKVLGELPVEVPSKQEEKHMTTVKGLPEQECEQQQQEPQEQELQQQHWEQHEEHQKAENPEQQLKQEKAQRDQQLNEHLEEEKKLLDQQLNQELIKRDEQLGIKKEQLLELTEQQEGQLEHLEQQEGQLELPEQQEGQLEHLEQQEGQLKHLDQQGKQPELPEQQVAQLKHLEQQEGQLKHLEHQKGELQVPEEQVGQLKYLEQQEGQLKHLDQQEKQPELPEQQVGQLKHLEQQEGQLEHMEHQEGQLGLPEQQVGQLKQLEEQEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQERQLEQQEGKVQHLEQQVEQLKHLEEQEGQLKHLEQQQGQLEVSEQQVGQPKHLEQEGKQLELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHPEQQEKQLEHPEQQEGQLKHLEQQEGQLKDLEQQKGQLEQQQGQLEQPVFAPAPGQVQDIQPVLPTKGEALLPVEQQQQKQEVQWPPKHK
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Involucrin.
What is the protein family that this protein belongs to?
Belongs to the involucrin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: ILVC_SORC5
Sequence: MAKIFYDNDADLSLIQSKKVAIVGYGSQGHAHALNLRDSGVTVIVALPEGSKSRPKAQAAGLQVATVSEAAKAADVIMILAPDTSQARIYNEQIAPHLGPGKTLMFAHGFNIRFNTITPPPSVDVSMIAPKGPGHRVRETFEAGGGVPALLAVHQDASGKAEAQALAYAKGIGATRAGVLLTTFAEETETDLFGEQAVLCGGASELVKAGFETLVNAGYQPEIAYFECLHELKLIVDLMYRGGLNYMRYSISDTAEHGDYVSGPRVITDKTREEMKRILAEIQSGEFARKWIAENEAGRPKFEATRAKEREQRLEIVGANLRKMMPFIDPVTIKPGD
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MYH16_HUMAN
Sequence: MGLKVIQQNVHKFLQLRFWGWWKLYNKVKPLLNVARQEEEMKAKEEELRKAMAQTQELVNKVKELEEKTATLSQEKNDLTIQLQAEQENLMDAEERLTWMMKTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTEKEKQALDHKVRTLTGDLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLSTQIHELEDNWEQEKKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKEHQDRIEELEEELEAERAMRAKIEQNRKREAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQAEINAIRTRLQAENSELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTEELEETKRKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQKLKKKLEMEKEELQVALEEAESSLEVEESKVIRIQLELAQVKADIDRRIHEKEEEFEATRKNHQRAIESLQASLEAEAKGRAEALRLKKKMETDLNEMEIQLDHANKNNSELVKTLKRLQQQIKDLQVQMDEDARQHEELRKQYNLQERRLSLLQTELEEVRSALEGSERSRKLLEQEVVEITEWHNEINIQNQSLLVVKRKLESDVQRISNEHEELISEFRLTEERAKKAMMDAARMAEELRQEQDHCMHLEKIKKNYEVTIKDLQAKMEEAEQLALKGGKRTIMKLEARIKELETELDGEQKQHVETVKTLCKNERRLKELVFQTEEDHKTNQRMQALVEKLQNKLKVYKRQIEEAEDQANQTLARYRKTVHELDDAEDRAGMAETALNKLRTRHRVAGKGITSV
What is the function of this protein?
Has most probably lost the function in masticatory muscles contraction suspected for its homologs in dog (AC F1PT61) and apes.
What are the official names of this protein?
Putative uncharacterized protein MYH16, Myosin heavy chain 16 pseudogene, myosin heavy polypeptide 5.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: ILVH_GUITH
Sequence: MKHTLSVLVEDESGVLTRIAGLFARRGFNIESLAVGPTEKLGISRITMVVPSDERTIEQLTKQLYKLVNILKVEDITNLPTVERELMLIKLRVSTFERTEALDIINIFRAKVVDLSEDFLIIEVTGDPGKIVAIEQILSKFTISEIVRTGKISLVRESNVNTRSLLKEY
What are the official names of this protein?
Acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRD_SALTY
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPLEALVRQKVPTKPVTCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSLEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICMEKVYAYAGYIAINISSPNTPGLRTLQYGDALDDLLTAIKNKQNDLQAIHHKYVPVAVKIAPDLCEEELIQVADSLLRHNIDGVIATNTTLDRSLVQGMKNCQQTGGLSGRPLQLKSTEIIRRLSQELKGQLPIIGVGGIDSVIAAREKIAAGATLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LHPP_RAT
Sequence: MAAWAERLSGVRGVLLDISGVLYDSGTGGGAAIAGSVEAVARLKRSPLKVRFCTNESQKSRRELVGVLQRLGFDISEGEVTAPAPATCQILKERGLRPHLLIHEGVRSEFDDIDMSNPNCVVIADAGEGFSYQNMNRAFQVLMELENPVLISLGKGRYYKETSGLMLDVGGYMKALEYACGIEAEVVGKPSPEFFRSALQAIGVEAHQAIMIGDDIVGDVGGAQQCGMRALQVRTGKFRPGDEHHPEVRADGYVDNLAEAVDLLLQHMDK
What is the function of this protein?
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine.  Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity).
What are the official names of this protein?
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.