PharMolix/UniProtQA huggingface dataset:
Protein: PLCD4_PIG
Sequence: MASLLQGLSASPGSGLPINQDLLLMQKGMLMRKVRSKSWKKLRYYRLQDDGMTVWHARQAGGRAKPSFSISDVETVRGGHESELLRNLAEEFPLEQGFTIVFHGRRSNLDLVANSVEEAQVWMQGLQLLVDFVTNMDQQERLDQWLSDWFQRGDKNQDGRMSFGEVQRLLHLMNVEMDQEHAFQLFQTADTSQSGTLEGEEFVEFYKSLTKRAEVQELFENFSSDGQKLTLLEFVDFLQEEQKEGERASDLALELIDRHEPSDSGKLRHVLSLDGFLSYLCSKDGDIFNPTCLPIYQDMTQPLNHYFINSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDIWDGPNGEPVVYHGHTLTSRIPFKDVVAAIAQYAFQTSDYPVILSLENHCSWEQQEMIAHHLTEILGEQLLSTTLDGQLPTQLPSPEELRRKILVKGKKLRTLEEDLEEEEEEPEESELEGEQEAELELEAQFESEPQELSPRSKDKKKKVKAILCPALSALVVYLKAVSFYSFAHSREHYRFYEISSFSEAKAKSLIKESGNEFVQHNTWQLSRVYPGGLRTDSSNYNPQEFWNAGCQMVAMNMQTAGLEMDLCDGLFRQNAGCGYVLKPDFLRDAQSSFHPERPISPSKAQTLLIQVISGQQLPKVDDSKEGSIVDPLVRVEIFGVRPDTARQETSYVENNGFNPYWGQTLCFRVLVPELALLRFVVKDYDWKSRNDFVGQYTLPWNCMQQGYRHIHLLSKDGISLHPASIFVHICIREGIEGVES
What is the function of this protein?
Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3).  DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores.  Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction.  May play a role in cell growth.  Modulates the liver regeneration in cooperation with nuclear PKC.  Overexpression up-regulates the Erk signaling pathway and proliferation (By similarity).
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4, Phosphoinositide phospholipase C-delta-4, Phospholipase C-delta-4, PLC-delta-4.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Localizes primarily to intracellular membranes mostly to the endoplasmic reticulum.
Protein: CYOE2_PSEP1
Sequence: MSVKHFIQITKPGIIFGNVLSVAGGFFLASKGHVDFALFLAVVIGTSLVVASGCVFNNCIDRDIDHKMERTKNRVMVQGGMSLPLALIYATLLGVAGFSLLYVQANPLSAFCALIGFVVYVGFYSLWLKRKSVHGTLVGSLSGAMPPVIGYCAVSNSFDLAAVTLLVMFSLWQMPHSFAIAIFRFKDYSAANIPVLPVARGILAAKKQIVLYVLAFVLATLMLTLGGYAGLGYLAVAAAMGLYWLYMAWGGYKAEDDSKWARKVFGFSILTVTALSVMMGVDSQTAADVLMTYAR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZNRF1_BOVIN
Sequence: MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRAGGGAMGLRSRSVSSVAGMGMDPSSAGGVSFGLYTPASRGAGDAERAPGSGGSASDSTYAHGNGYQETGGGHHRDGMLYLGSRASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKDAGECVICLEELLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation.  Plays a role in the establishment and maintenance of neuronal transmission and plasticity.  Regulates Schwann cells differentiation by mediating ubiquitination of GLUL.  Promotes degeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase ZNRF1, RING-type E3 ubiquitin transferase ZNRF1, Zinc/RING finger protein 1.
What are the subcellular locations of this protein?
Endosome. Lysosome. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Note=Associated with synaptic vesicle membranes in neurons.
Protein: NBR1_PONAB
Sequence: MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDSAVQSFPLATCDTDQPQDKPPDWFTSYLETFREQVVKETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLPLQPCTPVMPTLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDMTPCMSPLPHDSPLIEKPGLGQIQEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMKFALPEEGPLGNEREEIVHIAEEEAVMEEEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGEPGVEAGQEPAEAGERLPGGENQPQEHSISDIFTTSQTLETVPLIPEVVELPPPLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQPIVSEDQTAALMAHLFEMGFCDRQLNLQLLKKHNYNILQVVTELLQLNNNDWYSQRY
What is the function of this protein?
Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
What are the official names of this protein?
Next to BRCA1 gene 1 protein, Neighbor of BRCA1 gene 1 protein.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, autophagosome. Lysosome. Cytoplasm, myofibril, sarcomere, M line. Note=In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation (By similarity).
Protein: ERPA_XANC8
Sequence: MSTLVSLPTAAPAPDYQSIDRPLNFSNAAAAKVRELIQEEGNAELALRVYIQGGGCSGFQYGFEFDENRAEDDLAVATDGVTLLVDPLSLQYLMGAEVDYTESLTGAQFVIRNPNAKTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RL31B_CHLT3
Sequence: MKEGIHPKNYRPVVFQDLSNGDKFIVRSCIVTSETIKMEDGHEYPLSKVEITNASHPFFTGQQMLLDTAGRVERFNKRFGKMGKKS
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: CRRS1_ARATH
Sequence: MFSLPLHQSKLIFLLSFLLIKTLNAQPTYLLSYCYTSGNYTPNSSYKSNLDTLISVLDSQSSNKGFYSYASGSSPTTTVYGSYLCRGDISSSTCETCISRASKNVFIWCPVQKEAIIWYEECFLRYSSRKIFSILDQGPFVTWTSYDTTLYQFYFINTVEYRMDRLIQEAYSSSSYFAEETYHVSYLGEVYDLNGLVQCTPDLNQYDCYRCLKSAYNETKDCCYGKRFALVYSSNCMLTYKATFLAPPPPPPPPPPPPPPPQRLYGENDTPSSDESFSFKLGKVFRRIIAPVIAAVVIILVISVCSLCCCCIKKKKKANQREASIEIPTLNTGENLTVDHQ
What are the official names of this protein?
Cysteine-rich repeat secretory protein 1.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y5166_RALSO
Sequence: MLRYAVIFFIIALIAALFGFGGIAAGAAGIAKILFMIFVVLFVVSLFWGLVAGRG
What are the official names of this protein?
UPF0391 membrane protein RSp1666.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_STULI
Sequence: MTNIRKTHPLLKIINNSLVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTELVQWIWGGFSVDKATLTRFFAFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLIMLTALSALVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIIPILHMSKQRSMMFRPLSQCLFWLLVAVLLTLTWIGGQPVEHPYIIIGQTASVLYFLILLVLMPLTSITENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PG027_VACCW
Sequence: MGIQHEFDIIINGDIALRNLQLHKGDNYGCKLKIISNDYKKLKFRFIIRPDWSEIDEVKGLTVFANNYAVKVNKVDDTFYYVIYEAVIHLYNKKTEILIYSDDENELFKHYYPYISLNMISKKYKVKEENYSSPYIEHPLIPYRDYESMD
What is the function of this protein?
Inhibits antiviral activity induced by type I interferons.  Does not block signal transduction of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN.
What are the official names of this protein?
Interferon antagonist OPG027, Host range protein 2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG027 family.
Protein: RS10_PICTO
Sequence: MVYKARISLSGTENKIVDVVCEEIKGIAKRTGVEIHGPIPLPTKRLVVPVRKSPDGEGSPTWDRWEMRVHKRLIDVDADERTLRQLMRISIPDGVRIEIQIKS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NUOC_SALAI
Sequence: MNAPQDRTDDGGVPVPVTPAGATGGAPAELPPSSPAGRGMFGDQGTGDVSGYGGLVRPQRSIEAASRPYGGYFDEVADALEEAYPAFGEAIEKVVVDRGELTLHIRPERIAEVCQVLRDDLALRFELCSSVSGVDYLGADARRLHAVYQLTSMTYRRQIRLEAAVSVEDPHLPSVTGVYPTADWQEREAYDMFGIVFDGHPGLTRILMPDDWEGHPQRKDYPLGGVPVEYKGAEIPPPDRRRSYQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DMLR_ECOLI
Sequence: MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVTITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALLALAKAYPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGAPKHLTDLSALPCLVIKERDHPFGVWQLRNKEGPHAIKVTGPLSSNHGEIVHQWCLDGQGIALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVSRLATSAKVRITVEFLRQYFAEHYPNFSLEHA
What is the function of this protein?
Transcriptional regulator required for the aerobic growth on D-malate as the sole carbon source.  Induces the expression of dmlA in response to D-malate or L- or meso-tartrate.  Negatively regulates its own expression.
What are the official names of this protein?
HTH-type transcriptional regulator DmlR, D-malate degradation protein R.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RS13_STAAR
Sequence: MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CNN1_HUMAN
Sequence: MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIILCEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKGNKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNSA
What is the function of this protein?
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction.  It is capable of binding to actin, calmodulin and tropomyosin.  The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
What are the official names of this protein?
Calponin-1, Basic calponin, Calponin H1, smooth muscle.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
Protein: RRF_ONYPE
Sequence: MQQLAKDILASLETKMTQAQEVMLKNFCDIRTGTANPNILDKITVNYYGAPTFLKTLASISVSEGNQLNIKPYDSTLIPNIKKVLLASNLGITPQTDGLVVRLVFPKPTEERRKALMKEVEQLAEKTKVAIRNVRREGNDKIKKVELTKDLETFYLNQIQTLTDKNIKLIEKHTTTKNTELLKA
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPSF1_MOUSE
Sequence: MYAVYKQAHPPTGLEFTMYCNFFNNSERNLVVAGTSQLYVYRLNRDAEALTKNDGSTEGKAHREKLELVASFSFFGNVMSMASVQLAGAKRDALLLSFKDAKLSVVEYDPGTHDLKTLSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLIYGTRLVVLPFRRESLAEEHEGLMGEGQRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDTCSIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVIFAVNSLLYLNQSVPPYGVALNSLTTGTTAFPLRTQEGVRITLDCAQAAFISYDKMVISLKGGEIYVLTLITDGMRSVRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASSVREAADKEEPPSKKKRVEPAVGWTGGKTVPQDEVDEIEVYGSEAQSGTQLATYSFEVCDSMLNIGPCANAAVGEPAFLSEEFQNSPEPDLEIVVCSGYGKNGALSVLQKSIRPQVVTTFELPGCYDMWTVIAPVRKEEEETPKAESTEQEPSAPKAEEDGRRHGFLILSREDSTMILQTGQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQCAVADPYVVIMSAEGHVTMFLLKSDSYGGRHHRLALHKPPLHHQSKVIALCLYRDVSGMFTTESRLGGARDELGGRSGSEAEGLGSETSPTVDDEEEMLYGDSSALFSPSKEEARRSSQPPADRDPAPFKADPTHWCLLVRENGTMEIYQLPDWRLVFLVKNFPVGQRVLVDSSFGQPTTQGEVRKEEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRFKKVPHNINFREKKPKPSKKKAEGCSTEEGSGGRGRVARFRYFEDIYGYSGVFICGPSPHWLLVTGRGALRLHPMGIDGPIDSFAPFHNVNCPRGFLYFNRQGELRISVLPAYLSYDAPWPVRKIPLRCTAHYVAYHVESKVYAVATSTNTPCTRIPRMTGEEKEFEAIERDDRYIHPQQEAFSIQLISPVSWEAIPNARIELEEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQGEEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKIFLWSLRASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSRDAKPLEVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGAHVNTFWRTPCRGAAEGPSKKSVVWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPRAFRMLHVDRRILQNAVRNVLDGELLNRYLYLSTMERSELAKKIGTTPDIILDDLLETDRVTAHF
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.  This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).  May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity).
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the CPSF1 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: DNAJ_BURL3
Sequence: MAKRDYYEVLGVAKNAGDDEIKKAYRKLAMKYHPDRNPDNKDAEEHFKEVKEAYEMLSDGQKRAAYDQYGHAGVDPNMGGAGAQGFGGFADAFGDIFGDIFGQAAGGAARGGRGGPQVYRGADLRYSMEITLEQAAHGYDTQIRVPSWVSCEVCHGSGAKPGTKPETCPTCHGQGTVRMSQGFFSIQQTCPKCHGTGTYIPEPCVHCHGSGKVKETKTLEVKIPAGIDDGMRIRSAGNGEPGINGGPPGDLYVEIHIKPHSVFERDGDDLHCQMPIPFTTAALGGEIEVPTLAGRASFPVPEGTQSGKTFRLRGKGIKGLRSSIAGDLYVHVQVETPVKLTDNQRDLLKQFEKSLAEGGARHSPQSKSWFDRVKSFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_THEMA
Sequence: MRVGIKVLGCPKNEADCEVLAGVLREGGHEIVFDVKDADVVVLDTCAFIEDAKRESIDEIFSFVDAKDQYGYKLVVKGCLVQRYYEELKKEIPEVDQWIGVADPEEIANAIENGTDLVPDQPETVYRYRKRIDLEERPYAYVKISDGCDRGCTFCSIPSFKGSLRSRSIEDITREVEDLLKEGKKEIILVAQDTTSYGIDLYRKQALPDLLRRLNSLNGEFWIRVMYLHPDHLTEEIISAMLELDKVVKYFDVPVQHGSDKILKLMGRTKSSEELKKMLSSIRERFPDAVLRTSIIVGFPGETEEDFEELKQFVEEIQFDKLGAFVYSDEEGTVAFNLKEKVDPEMAKRRQEELLLLQAEISNSRLDRFVGKKLKFLVEGKEGKFLVGRTWTEAPEVDGVVFVRGKGKIGDFLEVVIKEHDEYDMWGSVI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_BURM7
Sequence: MGRRYFGTDGIRGKVGDAPITPDFVLRLGYAAGKVLASAPGRAASGARPTVLIGKDTRVSGYMLEAALEAGFSAAGVDVMLAGPMPTPGVAYLTRALRLSAGVVISASHNPYHDNGIKFFSADGNKLPDEIEAEIEAWLDKPLDCAASDGLGKARRLDDAAGRYIEFCKSTFPAAFDLRGMKLVVDCAHGAAYQVAPHVFHELGADVIPIGVAPNGFNINDGVGATAPDALMRAVRANHADLGIALDGDADRLLVVDHTGRLYNGDELLYVLVKDRIATNGQVEGAVGTLMTNFAVEVALKEAGVQFVRAAVGDRYVLEQLRERGWQLGAEGSGHILSLDRHSTGDGIVSALLVLAALKRSGKTLAQMLEGVTLFPQKLINVRMKPGADWKGSEAIRRAIDSAEQALSGSGRVLIRASGTEPVLRVMVEARQATDANRHAEAIADAVKQATA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: LPTD_FRATN
Sequence: MLKGIHKYLLMCFGTVLFTVQANAARIMSNNPIKEDWQCKVVDGEWSCKRAKKPKSVFDKKLTKTEKEKALADDLAWVKKPSYFVGGYYSNDSQFTKALCESKKTDLSYEKSEFDNDGTLIASGNVQVLQCDQELYGNNAIINLNSNNSAIRSLVMAGDVIVKQPSTGIVIRTTELDADMNDGTYSTGEAYFRLAREMPKTRIYDKEHFSGYLRGYAKTFKKESSGDIVLSDGYITSGDPYDNAWKITGNNIDIDTNTHMAYVKNGYFEIQDIPVMYIPYFSHPIDDRRRSGFLYPGFVQNANSGIGISVPYYFNLAPNYDLMLQSVIWSQRGIMENGTFRYMTKYFQGQFEGSLVPYDFKEGKMRGSFTLSTTGQYENINTNFKYEYVSDQNYYNDFSAGNVNLVTKTLLDREFDLTYTNDYVDSGLTVLDYGVVNPLLTVDNTPYAKLPEVKLNLTSDGYTPDYLTLSAQTLNTFFYKTAGPANTNPGAPQGTNVNAFRAYESPKIAFNFNKTWGYLNPSLEVPIRYYQLKNSPTDTIQFANSSVTSVLPIFNIDAGAYFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYDRINNANQLTYALEASTTNQEDGTTLASAKIGQMAYFADRKVNLCQGNSACPNPGLMDPFSTDTFSPIMTSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQLSYKDENENIFNVSYNNIANNWSSLTQQQIAEGAKPQPQETITLSTILNITDHWGIAALWNYNFQQKQIANIFAGLQYNAKSWAVRALWQKTAYTNQDPNNPTLLGPLVNTYMFEFELKGLGGIGNTSDISSRLQQINGYQVGEWGDGI
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: DCYD_YERPE
Sequence: MTLQQKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIGGSNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPKVAQIQQALATSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGPILFIHTGGAPALFAYHPQV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: END4_CHLCH
Sequence: MKRVGAHVSASGGVEQAPLNATAIGAKAFALFTKNQRQWKAPKLSKATIEAFQKACADGGFQPQHILPHDSYLINLGSPDPEKLERARSAFIDEMQRVADLGLQLLNFHPGSHLKEISEEASLLLIAESINMALEATNGVTAVIENTAGQGTNLGYRFEQIAFLIDRIEDKSRVGVCLDTCHLFASGYDLSSTEAIETTFNEFDSTVGLHYLRGMHLNDAMQPLGSRVDRHASLGKGTIGMAAFTFIMNHPACEEIPLILETPNPDIWSEEIALLYSLQQVD
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RLMH_PROM5
Sequence: MLKANRLSIYAIGKIKKKWIREGINQYKKRMPDLIINESKSFNIDNIRVNNIIICLTEEGKSFSSTELTSLLLNFKNKKINFLIGDADGIPSDIKDKSHLLLSLSPLTFPHELARLILVEQIYRVISISNGSPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTM1_MOUSE
Sequence: MPMILGYWNVRGLTHPIRMLLEYTDSSYDEKRYTMGDAPDFDRSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLARKHHLDGETEEERIRADIVENQVMDTRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYRMFEPKCLDAFPNLRDFLARFEGLKKISAYMKSSRYIATPIFSKMAHWSNK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2).  Participates in the formation of novel hepoxilin regioisomers.
What are the official names of this protein?
Glutathione S-transferase Mu 1, GST 1-1, GST class-mu 1, Glutathione S-transferase GT8.7, pmGT10.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.