PharMolix/UniProtQA huggingface dataset:
Protein: CCME_BRUA2
Sequence: MSATAEQNARNPKGKGGFARTVSQRKRKRLFLIGGALAVLAVAVGLMLTAFNQDIRFFRTPADLTEQDMTSGARFRLGGLVEEGSVSRTGSELRFTVTDTIKTVKVVFEGIPPDLFREGQGVVAEGRFGSDGLFRADNVLAKHDENYVPKDLADSLKKKGVWEGK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: AROK_MYCTU
Sequence: MAPKAVLVGLPGSGKSTIGRRLAKALGVGLLDTDVAIEQRTGRSIADIFATDGEQEFRRIEEDVVRAALADHDGVLSLGGGAVTSPGVRAALAGHTVVYLEISAAEGVRRTGGNTVRPLLAGPDRAEKYRALMAKRAPLYRRVATMRVDTNRRNPGAVVRHILSRLQVPSPSEAAT
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG160_MONPV
Sequence: MPSLFSSLLTTLVFHILIYYQINLVTVNIIMNCFQEKQFSRENLLKMPFRMVLTGGSGSGKTIYLLSLFSTLVKKYKHIFLFTPVYNPDYDGYIWPNHINFVSSQEALEYNLIRTKSNIEKCIAVAQNHKKSAHFLLIFDDVGDKLSKCNTLIEFLNFGRHLNTSIILLCQTYRHVPILGRANITHFCSFNISISDAENMLRSMPVKGKRKDILNMLNMIQTARSNNRLAIIIEDSVFCEGELRICTDTADKDVIEQKLNIDILVSQYSHMKKNLNTILESTKTKLCNSDQSSSSKNVSS
What is the function of this protein?
Participates in viral DNA packaging and virion morphogenesis.
What are the official names of this protein?
DNA packaging protein OPG160.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG160 protein family.
Protein: SFSA_BRUSU
Sequence: MLFPTPLISGRLERRYKRFLADVTLDDGRFITASVPNTGSMLGLTAPGSRVWLSFSDAPHRKYAHTLQIVEADNTLVGVNTGLPNRIAEEAILKGLIPDLDGYATLKREQKYGRNSRIDLLLDDGPRPRAYVEVKNVHFIRTPGLAEFPDTVTARGAKHLDELVDVVAAGHRGIMLFIIQRADCSRFGISGDLDPFYARAFERAIASGVEAWAVRCHITENGIDATELVPIEDMRRIE
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: MURA_SHEFN
Sequence: MDKLTIKASNPLAGEVVISGAKNAALPILMAGVLAETDFIVSNVPSLRDVITSCELLRCLGAEVEDLGGSRIRISTTNLNEYCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLELMGAKIEVKEGYIKARVDGRLKGTHIFMDMVSVGATENLLMAAALADGTTVIENAAREPEVTDLAHCLIAMGAKITGIGTATLKIEGVERLSGCEYRVMPDRIETGSFLVAAAVTRGKIRCVSADPSALEAVLSKLEDAGAEITTGEDWIELDMKGQRPKSVNIKTAPYPAFPTDMQAQFCVLNALAEGTGRVTETIFENRFMHVPELIRMGADIEQEGNTCIIHGIDRLNGAQVMATDLRASASLVIAGLMAEGTTTVDRIYHLDRGYEHIEAKFQGLGAEVVRVK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_MYCMM
Sequence: MLSARNRMRRSTEFDATVRQGVRTVQPDVIVHVRRAKECAADSSPRVGLIIAKSVGTAVERHRVARRLRHVARPMLMNLHPCDRVVIRALPSSRHVSSAWLEQQLRSGLRRAFESAGADR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: HYAS1_MOUSE
Sequence: MRQDMPKPSEAARCCSGLARRALTIIFALLILGLMTWAYAAGVPLASDRYGLLAFGLYGAFLSAHLVAQSLFAYLEHRRVAAAARRSLAKGPLDAATARSVALTISAYQEDPAYLRQCLTSARALLYPHTRLRVLMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAEATGAVGEGAYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSDTRLDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFHCVSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSRCYSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVLRLFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCVRMVLLSLYAPLYMCGLLPAKFLALVTMNQSGWGTSGRKKLAANYVPVLPLALWALLLLGGLARSVAQEARADWSGPSRAAEAYHLAAGAGAYVAYWVVMLTIYWVGVRRLCRRRSGGYRVQV
What is the function of this protein?
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer.  Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation.  This is one of the isozymes catalyzing that reaction.  Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.
What are the official names of this protein?
Hyaluronan synthase 1, Hyaluronate synthase 1, Hyaluronic acid synthase 1, HA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the NodC/HAS family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RF1_STRSV
Sequence: MNIYEQLQAVEDRYEELGELLSDPDVVSDTKRFMDLSKEEASTRDTVTAYREYKKVLQNITDAEEMIKDASGDADLEEMAKQELKDAKAEKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAQLFAGDLLQMYQKYAESQGWRFEVMEASYNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEIEEVEYDIDPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILAGKLDEVVDALVLYDQTQKLEELNK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BACVZ
Sequence: MPRKGPVAKRDVLPDPLYNSKLVSRLINKMMIDGKKGKSQTILYKSFDIIKERTGNDAMEVFEQALKNIMPVLEVKARRVGGANYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNTGAAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: IF1C_ANGEV
Sequence: MKKQDLIDMEGIVTESLPNAMFRVCLDNGCQVLTHISGKIRRNYIRILPGDRVRVELSPYDLTKGRIIYRLRNKYPNGISQEVFRSMRD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HUTI_BACCQ
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_THEAC
Sequence: MKERKFINEAVKRLLVCEYVVKETENAGFGNMVMKRTPFGTNITLYVNRPGLVIGRRGSKVQQMTDTLEKKYGIETPQIEVKDVKDPDLNPSVIAKKIALSLEKGWSYRKAGNTSLNRTIQAGAKGVLIKISGKISGERARYQKFIYGNVKYSGEPGSKGMITGFSTAKLKVGILGVTVKILNPEYKLPDVFSIENITGGEEVGTESKADQTDVEGRETGNAEES
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GSM1_YEAS1
Sequence: MTKKLPSELKQTRKSIQTACEFCHTKHIQCDVGRPCQNCLKRNIGKFCRDKKRKSRKRIEKHGTQPYLNLGKRLVIHDVPSKTVSPSSVHLQRDFLSSDQEKPGKTPAHNTNIQYTYNINDNFQSAGSIPRITNFNTNNGQTVLENTSNNISASQAVHLMNDPIIPTVRKSTLNLKSHFLEQHKAMQQPLATNCLVATSNVPVHSGMDDSNKSDDDVDDETNIHFDSMWCNDEYMKLKDIVDISTPFLPNNSQIFSLQESEYPNPSASTRGNSSLHLTNLLNSTKSVNDQKDSSIGHSTSTFNTYDEVVSRPFISLDMLHLNRGANANTHPSHNAKLESECDSSSHSDADLEKHDTDFISPSKFRELVKTPQDLYDNKCLIKPHNYKLAYTKLLTTLRKKFLEGAEIDKSASVKDEHSTQKHNLRYDLEVIIRSILERYAPIFISLTSNMIEEDLLLQEVTLQRALLDLENMAKLVSCTPMCIWRRSGEICFVSNEFYSLTGFNKNLLLDRTSFIFEYLDHKSVSNYFQIFNELLAFGYNDINKRKKLLMLNACSSTSSKITEGFSFTTDGKAIFTKCNLLLSNGLYLKCACCWTVKRDSFNIPILVMGQFLPIFEMD
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Binds specifically to 5'-CGGN(8)CGG-3' and 5'-CGGN(9)CGG-3' sequences in the promoter region (By similarity).
What are the official names of this protein?
Glucose starvation modulator protein 1.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2916_BORPE
Sequence: MPSFDVVSEVDKHELTNAVDQANRELSTRFDFKGTNASFELEGYVVTQVAPSAFQLKQMLDILRGRLSARSIDVRCMDVADPLENLGGARQKVTIKQGIEQAIAKKLIAAIKASKVKVESQINGEKLRITGKKRDDLQAVIALLRKTDVDLPLQFENFRD
What are the official names of this protein?
UPF0234 protein BP2916.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: CYSG_ECOHS
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: PSBN_ALLOC
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y6021_STRCO
Sequence: MTTVSDFTAHQTATAVVARKGTAGPRPSAVDAPATLTDEHGDVYVEPGLTPLAAREANRSALVGLLDAAGVGHFAVRGTVDHGTVVGVAEEDRERALQAVFRGLGQYPGHLSVVDPDAPRPAKPVSSRDPRAWREVVGARILQVSWYRTDPGRHLLLGHEYGCALEFWRRQGTCLVAPRANRATWAVAVGGPNVMGAARLFSRFVSDWTPGHLAPALPTRPEFLVNCADDIAFPVDAVYTWVDGNDPAWKQRKAQAKGEVYHAESASDARFISRDELRYSIRSLHLFAPWIRNIYVVTDDQVPAWMREDLPGARIATHREIFRNPEDLPTFNSHSIESQLHHIEGLAEHFLYFNDDMFMGRPVAPHSFFTPNGTARYFPSRNRIPQGAVAETDSPVDAACKNNRALLHERFGKVITQPMEHIPYALRRSAMAEAELEFPEAWARTSASRFRAMTDLSPTSSFALYYAALTGRAQPGSMPFTYIQLAVPDLADRLQRLLDGRDQDSFCLNDAFSTPEDTEAQQELLDDFFTSYFPTPSPYER
What are the official names of this protein?
Exopolysaccharide phosphotransferase SCO6021, Stealth protein SCO6021.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: Y1516_METJA
Sequence: MMAMNEIELMQIKDFVKDMDKNQRIVYYEQKKKSVGIAVLLSFIIPGAGQMYLGRVGKGIILLLTCWLIIPWIYSIYDAYKSAKDYNAQLYSIIFSKDD
What are the official names of this protein?
Uncharacterized protein MJ1516.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL10_GEOTN
Sequence: MSSAIELKKQVVAEIADKFRASKATVIVDYRGLNVAEMTELRKQLREAGIEFKVYKNTMTRRALAEIGLEGLDEVFTGPNAIAFSNEDVVAPAKILSEFAKTHEALEIKGGVIEGSVASKEEIDALAKLPSREGLLSMLLSVLQAPIRNFALAVKAVADKQEEQGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL28_DICT6
Sequence: MSRRCEICGKGPWTGLQVSHSHRRTKTRWLPNLHKVRALVNGKVKTIKVCTRCLKAGKVQKVV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PSBB_EUGGR
Sequence: MGLPWYRVHTVVLNDPGRFISVHLMHTALVSGWAGSMALYELAIFDPSDVALNPMWPQGMFVLPFMTRLGVTKSWGAWSVTGESFSDPGIWSYEGVAVAHIILSGLLFLAAIWHWVYWDLDLFRDPASGELKLDLPRVFGVHLFLSGALCLAFGVFHVTGVFGPGIWVSDPYGLSGKIEPVIPSWGAEGFDPYNVGAIASHHIAAGLLGLIAGGFHVLVRPSQRLFVLLRMGNIETVLSSSIAAVFWSAFVVSGTMWYGSASTPIELFGPTRYQWDKGYFQEEIERRVQASLSDGCSLSEAWGAISPKLAFYDYIGNNPAKGGLFRSGPMNNGDGIATAWLGHAVFIDKEGNSLFVRRMPTFFETFPVILLDQNGVVRADIPFRRAESKYSIEQVGVTVRFFGGSFDTLSFNDPATVKRYARHAQLGEIFDFNRSILQSDGVFRSSPRGWFTFGHLSFALIFFFGHIWHGARTLFKYLLAGIDPHLEEEIEFGTFEKLGDDTTKKELV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TBCD5_MOUSE
Sequence: MYKSVSETRHPLQSEEQEVGIDPLFSYSNKTRGDLSQNGRGSNSTLDTEGTFNSYMKEWEELFVNNNYLATVRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISKIKELRAWYSSIKEIHITNPRKAAGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIIFTLHCDHQAFLHASESAQPSEEMKTLLNPEYLEHDAYAMFSQLMETAEPWFSTFEHDGQKGKETLMAPIPFARPQDLGPTVAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADSLNLSLVDYVFTAMLLYIRDALISSNYQTCLGLLMHYPIIGDIHSLILKALFLRDPKRNPRPATYQFHPNLDYYKARGADLMNKSRTNARGAPLNIHKVSNSLINFGRKLISPASAPGSMGGPVPGNNSSSSFSAAIPTRTSTEAPRHHLLQQQQQQQHQQQQQQQPQQQQQQHQQQQQQQRLMKSESMPVQLNKGQSSKTISSSPSIESLPGGREFTGSPPPSATKKDSFFSNIARSRSHSKTMGRKESEEELEAQISFLQGQLNDLDAMCKYCAKVMDMHLVNIQDVVLQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQLEAGENEQITIADDHYCSSGQDQGSQVPRAAKQASSEMPGCTGGTTPDDFILVSKEDEGHRARGAFSGQAQPLLTLRSTSGKSRAPACSPLLFSDPLMGPASASASSSNPSSSPDDDSSKESGFTIVSPLDI
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s).  May act as a GAP for RAB7A.  Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity.  Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN); the function seems to require its catalytic activity.  Involved in regulation of autophagy.  May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction.  Involved in the trafficking of ATG9A upon activation of autophagy.  May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes (By similarity).
What are the official names of this protein?
TBC1 domain family member 5.
What are the subcellular locations of this protein?
Endosome membrane. Cytoplasmic vesicle, autophagosome. Note=During starvation induced autophagy is relocalized from endosomal localization to LC3-positive autophagosomes (By similarity).
Protein: NDX1_CAEEL
Sequence: MPLGKLDLVEEEYIAESGDHTPEASRLMGNGDSVVENLNGHTNGAVAKKKNEPRVPDMQLGKCRYVRLHDNVNYVAAAIILRNQGDDTEVLLIQEAKKSCRGKWYMPAGRVEAGETIEEAVVREVKEETGYSCDVVELLSLQVQGSGWYRYAFYCNITGGDLKTEPDQESLAAEWYNIKDLKANKVQLRGRDFIRLVDEAVTYRTHGPVDSIPRVMPLNQNVAGLFLEFMIVKHSRDGLRTEVLVHKSIKDETYLLEEEQPFPTVEFGFEYFFAMVVSKCYRHLLEEGANVVFTPSHVTRIKCHPKPMESLAHGVSIRVYCEHKQSASKAIIRSPRYHWISVESPETRQRFHMAQKQFRPSLHML
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Putative nudix hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: MNME_SALCH
Sequence: MSHNDTIVAQATPPGRGGVGILRISGLKARDVAQEVLGKLPKPRYADYLPFKDVDGSALDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTLPGVRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNGVIADLDAVRTEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPADIWPDFIARLPKNLPITVVRNKADITGETLGISEVNGHSLVRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALAEAAEHLEQGKAQLLGAWAGELLAEELRLAQQSLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_COXB2
Sequence: MDYQTIPSQGLSGEICVPGDKSISHRAVLLAAIAEGQTQVDGFLMGADNLAMVSALQQMGASIQVIEDENILVVEGVGMTGLQAPSEALDCGNSGTAIRLLSGLLAGQPFNTVLTGDSSLQRRPMKRIIDPLTLMGAKIDSTGNVPPLKIYGNPRLTGIHYQLPMASAQVKSCLLLAGLYARGKTCITEPAPSRDHTERLLKHFHYTLQKDKQSICVSGGGKLKANDISIPGDISSAAFFIVAATITPGSAIRLCRVGVNPTRLGVINLLKMMGADIEVTHYTEKNEEPTADITVRHARLKGIDIPPDQVPLTIDEFPVLLIAAAVAQGKTVLRDGAELRVKETDRIAAMVDGLQKLGIAAESLPDGVIIQGGTLEGGEVNSYDDHRIAMAFAVAGTLAKGPVRIRNCDNVKTSFPNFVELANEVGMNVKGVRGRGGF
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX621_POEME
Sequence: GGCRYFLGGCSEHSDCCEHLRCKMGLNYCAWDGTF
What is the function of this protein?
Gating-modifier toxin with weak activity on Nav1. 7/SCN9A and Nav1. 8/SCN10A (PubMed:32092883).  Inhibits Nav1. 7/SCN9A peak current (IC(50)=334 nM) and shifts the voltage dependence of activation to more depolarised membrane potentials (PubMed:32092883).  Shows 21% peak current inhibition (at 10 uM) on Nav1. 8/SCN10A sodium channels (PubMed:32092883).
What are the official names of this protein?
Mu-theraphotoxin-Pm1a, Mu-TRTX-Pm1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 62 (Vatx) subfamily.
Protein: AGRB_STAS1
Sequence: MVKFIDAKIDNFAKQLQQRNNLDRIEYLKMRLGMQVVVNNFFKTIVIYGVSLLCHMFLYTLTVHLTFFFIRHFAHGAHAKNSLLCYIQSVIYFVLLPWIVGYVQVSSLIMYTLALVGLIIISIYAPSATKKQPIPERLRRGKKIKAICLTLIFLLISLFLNEPYQQLMLLGIVIISILQFPIFFPKEDY
What is the function of this protein?
Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP).  This quorum sensing system is responsible for the regulation of the expression of virulence factor genes.  Involved in the proteolytic processing of AgrD, the precursor of AIP.
What are the official names of this protein?
Accessory gene regulator protein B.
What is the protein family that this protein belongs to?
Belongs to the AgrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAM_NITHX
Sequence: MDDWSAEQYLKFEDERTRPSRDLLAQVPLSAPRKAVDIGCGPGNSTELLVERWPQAEIIGIDTSADMLRRARERLPGQTFIEANVAHWVPPANTDLLFANAIFQWVPEHLRQLQRLLGALPSGGVLAVQMPDNLDEPSHVMMREVAHSGPWRETLADAARAKDVLPRPGAYYDALRPLCQHIEIWHTIYNHVLADTAAIVEWVKGTGLRPFVDPLEPTERKEFLREYTARIAAAYPLQADGKVLLRFPRLFVVAIK
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TREA_BOTFB
Sequence: MTSPLRKHRTSSVSSEIDPFAAAHVYYSNDTNQKSFRQARTRTYSSNQGIFSTPISGLEKPKRRGSHDDIGDHGRKFLIQVDSTLEALRKQEDTDDNHQITIEDVGPKSLPLGTATSNGFRRYDIRGTYMLSNLLQELTLAKENGREQIILDESRLNENPVNRLSRLIQGSFWDGLTRRIDGSVIEIAGRDPKDWTDDPRPRIYIPRGAPEQHAYYTKVATDRPEVRLDVCWLPEKITPEVVRDMNSKPGLLAVAMEEVIDPSTGEKTLKGLPFVVPGGRFNELYGWDSYMESLGLIVNDKVHLAKSMVQNFCFCIEHYGKILNATRSYYLCRSQPPFLTDMALRVFDKIKHEPGSLDFLKTAILAAIKEYHSVWTAEPRYDPVTGLSRYRPEGLGVPPETEASHFEHLLAPYAEKYNMTFKEFVDAYNNGRVVEKELDDYFLHDRAVRESGHDTSYRLERVCADLATIDLNSLLYKYEKDIAYTIRTFFQDKLEVPAEFCVGDMTPGQLQTSSMWDRRARGRKLAIDKYLWNKEKGMYFDYNTLKKEQCTYESATTFWAMWAGVASPQQAASLVTNALPKFEAAGGLLSGTEESRGAVGLDRPNRQWDYPYGWAPQQMLAWTGLLRYNYQEDAERLAYKWLFMITTAFVDFNGVVVEKYDVTRVVDPHKVDAEYGNQGSDFKGVAKEGFGWVNASYVYGLQIINAHMRRTLGTLTPWDQYNKAMNL
What is the function of this protein?
Hydrolyzes intracellular trehalose to glucose (PubMed:16946258).  The disaccharide trehalose serves as a storage carbohydrate that is mobilized during conidial germination (PubMed:16946258).  Regulates the level of trehalose as a protectant for cell integrity (PubMed:16946258).
What are the official names of this protein?
Cytosolic neutral trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase, Bctre1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_CORA7
Sequence: MKLILTAAVENLGAPGEIVEVKDGYGRNYLLPRGLAIVATRGAEKQIEGIKRAQEARAIRDLDHAREIRTQLEELKDVNVPVKTSESGKLFGSVSAEDIVNAVAAAGGPKLDKRIVVLPKGLVKKTGNYQVELKLHADVIGKVNFSVVAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.