PharMolix/UniProtQA huggingface dataset:
Protein: FBXW5_HUMAN
Sequence: MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
What is the function of this protein?
Substrate recognition component of both SCF (SKP1-CUL1-F-box protein) and DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes.  Substrate recognition component of the SCF(FBXW5) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SASS6 during S phase, leading to prevent centriole reduplication.  The SCF(FBXW5) complex also mediates ubiquitination and degradation of actin-regulator EPS8 during G2 phase, leading to the transient degradation of EPS8 and subsequent cell shape changes required to allow mitotic progression.  Substrate-specific adapter of the DCX(FBXW5) E3 ubiquitin-protein ligase complex which mediates the polyubiquitination and subsequent degradation of TSC2.  May also act as a negative regulator of MAP3K7/TAK1 signaling in the interleukin-1B (IL1B) signaling pathway.
What are the official names of this protein?
F-box/WD repeat-containing protein 5, F-box and WD-40 domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the FBXW5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLS1_TRYBB
Sequence: MISYPFFSLSPPGLVPPPMAVPPVEMYSGSFWNRMRKPLPLRTQVIRFTVVFVIVSFILAVALQITHERMPDPKVTKPLPDLGFELLTKISFLSVVTDVLIAFLSLLSFFTLWKLYLLHRHCVGSGEPELPCNIPGVSRFFLSVWLCKENCRIELRNIHTIAWIRFITSYALLLLFRSLVIVMTSMPTPVDKCQDPPKIENPVKNVILTVLTAGGGSIHCGDLMVSGHTVILTLHLMFHWIYGAMVHWSFRPVVTVVAIFSYYCIVASRSHYTDDVLVAIYLTIATFIAVGHNADGAPWQLQLFIRWLPCCGANSREVTEDSQPVMVAFKSEAVDELRERDDSAGLSGEVSTNEV
What is the function of this protein?
Predominantly synthesizes inositol phosphorylceramide (IPC), with minimal sphingomyelin (SM)/ethanolamine phosphorylceramide (EPC) synthase activity (PubMed:20457606, PubMed:19545591, PubMed:21899277).  Specificity is likely to be defined by residues in the lumenal catalytic domain that interact with the polar head groups of the phospholipid donors (PubMed:21899277).  IPC is synthesized by transferring the phosphoinositol from a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) to an N-acylsphing-4-enine (ceramide) or an N-acylsphinganine (dihydroceramide) (PubMed:20457606).  SM is synthesized by both stages of the parasite life cycle, bloodstream forms (BSF) and procyclic forms (PCF), by transferring the phosphocholine from a 1,2-diacyl-sn-glycero-3-phosphocholine to an N-acylsphing-4-enine (ceramide) or an N-acylsphinganine (dihydroceramide) (By similarity).  Similarly, EPC is synthesized by transferring phosphoethanolamine from a 1,2-diacyl-sn-glycero-3-phosphoethanolamine to ceramide or dihydroceramide by BSF and PCF, while IPC is confined to PCF (By similarity).  The ceramide/dihydroceramide ratios are skewed towards dihydroceramide in PCF parasites and ceramide in BSF parasites, this is likely due to differential expression and/or regulation of dihydroceramide desaturase, the enzyme responsible for converting dihydroceramide to ceramide (PubMed:18699867).
What are the official names of this protein?
Phosphatidylinositol:ceramide inositolphosphotransferase, TbSLS1, Inositol-phosphorylceramide synthase, IPC synthase, Sphingolipid synthase.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MIAA_PSYCK
Sequence: MTIKGKYMRLSSDSLSSYLSPNLADNSVVCLMAPTASGKTALAYELYNSGRYELISVDSALVYRDMTVGTAKPNAAELARYPHHLVDIIDPMQSYSVAEFVNDVARLIDSCHQNGKIPLLVGGTMMYYMALLDGLSPVPDSDDSVRARVEQWRQDEGISALYDYLGKVDAISHERLNATDTQRITRAVEVYLQTDIPISDWQRQPKQALAYNPNQQWHALAVMPDRPWLHTRIEQRLDIMWREGLVAEVISLLEHYPLTPGLPSMRCVGYRQVLEYLVQTNHPVFEQPHLDKAQFYDAFAQSEPSSNESKEQDTTIQSSITQTHLPMATAQTEALACQQMQNKALYATRQLAKRQYTWLRKVMQLSNTAAVPTTESITASSTSTVGSDDVTDFQKNKLILHSFSTMEQARAYLV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: IF2AH_ARATH
Sequence: MASQTPNLECRMYEAKYPEVDMAVMIQVKNIADMGAYVSLLEYNNIEGMILFSELSRRRIRSVSSLIKVGRIEPVMVLRVDKEKGYIDLSKRRVSEEDIQTCEERYNKSKLVHSIMRHVAETLSIDLEDLYVNIGWPLYRRHGHAFEAFKILVTDPDSVLGPLTREIKEVGPDGQEVTKVVPAVTEEVKDALVKNIRRRMTPQPMKIRADIELKCFQFDGVVHIKEAMKNAEAAGNEDCPVKIKLVAPPLYVLTTQTLDKEQGIEILNKAIAACTETIETHKGKLVVKEGARAVSERDEKMLTEHMAKLRLDNEEMSGDEDSGDEEEDTGMGEVDLDAGAGIIE
What is the function of this protein?
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.  This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex.  Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit alpha homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: MIO_PONAB
Sequence: MSGTKPDILWAPHQVDRFVVCDSELSLYHVESTVNSELKAGSLRLSEDSAATLLSINSDTPYMKCVACYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDNNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECTEEENDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNEDPQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQSDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGERERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTGEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSETGSYDGVLYENKVAVRDRVAFACKFLSDTQLNRYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAVPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINTGTPVSSCPGGTKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP
What is the function of this protein?
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway.  Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex.  It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
What are the official names of this protein?
GATOR complex protein MIOS.
What is the protein family that this protein belongs to?
Belongs to the WD repeat mio family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: RBFA_CHLAA
Sequence: MAKHRLQQVADTMQRVLGDVIQKELKDPRVGFATVTGVEVSADLQHAKVRISVMGSPEEREAAMAALQRARGFLRKRVAEEMSYMRFVPELHLIQDTSLDYTMHMDEVFRAIQHERLVNPPKLDDEQ
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUNB_TRICA
Sequence: MIDKDMNSACMRGGSVRTLNNYQQVMEPRSPHTAWQFGVSQIVKREPMDEDKNDSGVTSGSDFHSSSPSSDTSQDLQHSYQSPQTQPARFYSTPIVPHFAYNHNPLTPPNSEPLVSPKSEKEEKDMETTLTPCASPNRKPDDNQDHLRRLEMSLEKSGLFSSKTSEHSVDELSGKSDNDAEEYDEQSLRVPKVNSHGKIKTFKCKQCDFVAITKLEQWNHSKVHIREDKRLTCPKCPFITEYKHHLEYHLRNHAGSKPFQCNKCDYTCVNKSMLNSHMKSHSNVYRYSCRDCSYATKYCHSLKIHLRRYGHTPNVVLDEEGNPCPDIIIDVHGTRRGPKIKTQPKAEEAKPETLPFLNLQQQLPFPGYPFFGGFPNAQLLQQLIRERQLAVGGSQEESRVLDLSKPGCSYTGEQKSRRKGPAFKVDPTQVESEEEDEETSTTVFSNVEVVQEEAKKEESDSNNNNNKEEGNSCQYCNIAFGDAVLYTIHMGYHGFHNPFTCNMCGVECSDKVSFFLHIARVSHS
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS2_BORA1
Sequence: MTNAPVFGADVLARVADTLETRLPQNGGDPQTSYAAKLLAKGPDAFLKKIGEEATELVMAAKDGRPERIVSETADLWFHCLVTLAHYNLRPEDVLAELARREGLSGLEEKARRPAD
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF2_OLIPU
Sequence: MKGHQFKSWIFELREIVREIKNSHYFLDSWTQFNSVGSFIHIFFHQERFRKLLDPRIFSILLLRNSQGSTSNRYFTIKGVVLFVVAALLYRINNRNMVESKNLYLKGLLPIPMNSIGPRNDTSEESFGSSNINRLIVSLLYLTKGKKISESCFRDPKESTWVLPITQKCIMPESNWSSRWWRNWIGKKRDFCCKISNQTVAGIDISFKEKDIKYLEFLFVYYMDDPIRKGHDWELFDRLSPSKRRNIINLNSGQLFEILVKDWICYLMFAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFHQDLFVSWGKNPHESDFLRKISRENWIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSSFVQVTDSSQLNGSSDQFIDPFDSISNEDSEYHYHTLINQREIQQLKERSILLDPSFIQTEGREIESDRFPKYLSGYSSMPRLFTEREKRMNNHLLPEESEEFLGNPTRAIRSFFSDRWSELHLGSNPTERSTRDQKLLKKEQDVSFVPSRRSENKEIVNIFKIITYLQNTVSIHSISSDLGCDMVPKDELDMDSSNKISFLNKNPFFDLFHLFHERKRGGYTLRHESEERFQEMADLFTLSITEPDLVYHKGFAFSIDSYGLDQRQFLKEVFNFRDESKKKSLLVLPPIFYEENESFYRRIRKNWVRISCGNYLEDPKRVVFASNNIMEAVNQYRLIRNMIQIQFQYSPYGYIRNVLNRFFLMKRPDRNFEYGIQRDLIGNDTLNHRTIMKDTINQHLSNLKKSQKKWFDPLIFLSQTERSINRDPNAYRYKWSNGSKNFQEHLEHFVSERKSRFQVVFDQLCINQYSIDWSEVIDKKDLSKSLRFFLSKLLRFFLSKLLLFLSKLLLFLSNSLPFFFVSFENIPIHRSEIHIYELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHNTSQKSKFLINGGTISPFLFNKIPKWMIDSFHTRKNRRKSFDNTDSYFSIVSHDQDNWLNPVKPFQRSSLISSFSKANRLRFLNNPHHFCFYCNKRFPFYVEKARLNNSDFTYGQFLTILFIHNKIFSSCGGKKKHAFLERDTISPSSIESQVSNIFISNDFPQSGDERYNLYKSFHFPIRSDPLVRRAIYSIADISGTPLIEGQRVNFERTYCQTLSDMNLSDSEEKSLHQYLNFNSNMGLIHTPCSEKYLQRKKRSLCLKKCVDKGQMDRTFQRDSAFSTLSKWNLIQTYMPWFFTSTGYKYLNLIFLDTFSDLLRILSSSQKFVSIFHDIMHGLDISWRILQKKLCLPQRNLISEISSKSLHNLLLSEEMIHRNNESSLISTHLRSPNVREVLYSILFLLLVAGYIVRTHLLFVSRAYSELQTEFEKIKSLMIPSYMIELRKLLDRYPTSELNSFWLKNLFLVALEQLGDCLEEIRGSGGNMLWGGDPAYGVKSIRSKKKDLKINFIDIIDLISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVSGDWIDDKIESWVANSDSIDDKEREFLVQFSTLRAEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGTIYLRYLVDIHKKYLMNYEFNTSCLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSPSRSILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFFIDDIDIDDSDDIDASNDIDRELDTELELLTMMNALTMDMMSEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESSYLALGLLVNSLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFESITMGSSARDLVALTNEALSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLISNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKKFTILLYLLSCSAGSVAQDLWSLPVPDEKNRITSYGFIENDSDLVHGLLEVQGALVGSSRTEKDCSQFDNDRVTLLFRSEPRDPLYMMQDGSCSIVDQRFLYEKYESEFEEGEGEGVLDPQQIEEDLFNHIVWAPRIWRPRGFLFDCIERPNELGFPYLAGSFRGKRIIYDEKYELQENDSEFLQSGTMQYQRRDRSSKEQGFFRISQFIWDPADPLFFLFKDQPFVSVFSHREFFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLIQRQRWLRTNSSLSNGFFRSNTRSESYQYLSNLFLSNGTLLDRMTKTLLKKRWLFSDEMKTGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GPBL1_MOUSE
Sequence: MAQHDFVPAWLNFSTPQSSKSSTATFDKHGEHLSRGEGRFGISRRRHNSSDGFFNNGPLRTTGDSWHQPSLFRHDSVDSGVSKGAYAGTTGWHGSSRGHDGMSQRSGGSSTGNHRHWNGSFHSRKGCAFQEKTPTEIREEKKEDKVEKLQFEEEDFPSLNPEAGKQNQPCRPVGTPSGVWENPPSAKQPSKMLVIKKISKEDPAAAFSAAFTSSGSHHANGNKVSTMVPSVYKNLVPKPAPPPSKPNAWKANRTEHKPGSLCSSRESAFTNPISVTKPVGLAAGAGLHSPKESPSSTTPPIEISSSRLTKLTRRTTDRKSEFLKTLKDERNGDCSESRDCDKLEGLRLEGSHTPEPKENGEQGCLQNGLSLPMVEEGEVLSHSLEAEHRLLKAMGWQEYPENDESCLPLTEDELKEFHLRTEQLRRNGFGKNGLLQSRSCSLSSPWRSTCIAECEDSDSETSSSQTSDDDAWK
What is the function of this protein?
Possible transcription factor.
What are the official names of this protein?
Vasculin-like protein 1, GC-rich promoter-binding protein 1-like 1.
What is the protein family that this protein belongs to?
Belongs to the vasculin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF1_BURCM
Sequence: MKTSMQRKLDQLSTRLAELNDLLSRENVTADLDQYRRLTREHAELGPVVEQYALWRQSRNDETAAQELLADASMRDFAEDEIRSARERMVRLEAELQKMLLPKDPNDDRNIFLEIRAGAGGDESALFAGDLLRMYLRFAERQRWQVEMMSESASDLGGYKEVIVRIAGQGAYSRLKFESGGHRVQRVPATETQGRIHTSACTVAVMPEADEIGEVEINPADLRIDTFRASGAGGQHINKTDSAVRVTHIPTGIVVECQDDRSQHKNKDRALKVLAARIKDKQYHEQHAKEAATRKSLIGSGDRSERIRTYNFPQGRMTDHRINLTLYRLEALMDGDLDELIGALVTEHQAELLASLGDTD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRL12_ORYSJ
Sequence: MAATAAQAVAVKGSVAVPPCGSRGRRRGAVASVRMAAAAATSALRIGRRSPFLGRRLAVGPRRSRPVPRNLVAPVQMNLAFAKATKWWEKGLQPNMREVESAQDLVDSLTNAGDNLVIVDFFSPGCGGCRALHPKICQIAEQNPDVLFLQVNYEEHKSMCYSLHVHVLPFFRFYRGAQGRLCSFSCTNATIKKFRDALAKHKPDRCSLGPTRGLEESELLALAANKDLQFNYTKKPELVPSGDAAAAQELDRGSTKLSPPAKPLVKQGSEERSLVSSGR
What is the function of this protein?
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.
What are the official names of this protein?
Thioredoxin-like 1-2, chloroplastic, Lilium-type thioredoxin 1-2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PS4_PSEPD
Sequence: GINTLKKVIQGLHEVIKLVSNHA
What is the function of this protein?
Possesses antifungal activity against C. albicans and is also active against E. coli and S. aureus.
What are the official names of this protein?
Pseudin-4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Pseudin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PANC_DESVV
Sequence: MQIITEPQTIQQACLRWRADGVHTALVPTMGYYHAGHESLMAHARAVSEKVIVSLFVNPAQFGPGEDFAAYPRDLERDAAMAEAQGVDVLFAPKAEDLYKKDHATWVEVPALSQTMCGLSRPTHFRGVCTVVTKLLMLTMPRIAVFGQKDWQQVAVIRRMVRDLNIPVDIVGRPIVREPDGLAMSSRNIYLTAEERLQAPHIHHGLALGRAITQSGERDAETIKTAIRRYWAQNLPGGEEDYLTIVDPVSLEPVDRLTGATLCATAVRVGQARLLDNMMLLGD
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y964_NEIMB
Sequence: MAQTTLKPIVLSILLINTPLLAQAHETEQSVDLETVSVVGKSRPRATSGLLHTSTASDKIISGDTLRQKAVNLGDALDGVPGIHASQYGGGASAPVIRGQTGRRIKVLNHHGETGDMADFSPDHAIMVDTALSQQVEILRGPVTLLYSSGNVAGLVDVADGKIPEKMPENGVSGELGLRLSSGNLEKLTSGGINIGLGKNFVLHTEGLYRKSGDYAVPRYRNLKRLPDSHADSQTGSIGLSWVGEKGFIGVAYSDRRDQYGLPAHSHEYDDCHADIIWQKSLINKRYLQLYPHLLTEEDIDYDNPGLSCGFHDDDNAHAHTHSGRPWIDLRNKRYELRAEWKQPFPGFEALRVHLNRNDYRHDEKAGDAVENFFNNQTQNARIELRHQPIGRLKGSWGVQYLQQKSSALSAISEAVKQPMLLDNKVQHYSFFGVEQANWDNFTLEGGVRVEKQKASIQYDKALIDRENYYNHPLPDLGAHRQTARSFALSGNWYFTPQHKLSLTASHQERLPSTQELYAHGKHVATNTFEVGNKHLNKERSNNIELALGYEGDRWQYNLALYRNRFGNYIYAQTLNDGRGPKSIEDDSEMKLVRYNQSGADFYGAEGEIYFKPTPRYRIGVSGDYVRGRLKNLPSLPGREDAYGNRPFIAQDDQNAPRVPAARLGFHLKASLTDRIDANLDYYRVFAQNKLARYETRTPGHHMLNLGANYRRNTRYGEWNWYVKADNLLNQSVYAHSSFLSDTPQMGRSFTGGVNVKF
What is the function of this protein?
Probable receptor, TonB-dependent.
What are the official names of this protein?
Probable TonB-dependent receptor NMB0964.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: YR596_MIMIV
Sequence: MSLSKQVVPTHRVEIAPNSESTCKMDHSNYQHNGLITKIWGTAGWTFNHAVTFGYPLNPTSDDKRRYKNYFISLGDVLPCRLCRESYKKFITTGKTALTNEVLRNRHTLTKWFYDVHNAVNNKLEVDYGLSYEDVVNKYESFRAKCGKPVPTVKGCVTPLDHKAFSFKKLYYMDAPIVSLDKVENFVRIARMRGISDKYFCFLELATVLNGDFNELKKQSSWEYRNKYCQKKIRHMRENAIPSIEEQGYWKGTPTIDELKLLLFLCSNLNRTEVNDAINNVERLESTHYIEN
What is the function of this protein?
FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.
What are the official names of this protein?
Probable FAD-linked sulfhydryl oxidase R596.
What are the subcellular locations of this protein?
Virion.
Protein: RL27_GLUDA
Sequence: MAQKKAGGSSRNGRDSAGRRLGVKKFGGETVVAGNIIIRQRGTKMKPGSNVGLGRDHTIFALVDGHVKFERRAEGRVHVSVEALPVAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ATPA_NEPOL
Sequence: MVKIRPDEISNIIRQQIEQYSQEVKVVSVGTVLQVGDGIARIYGLEKVMAGELLEFEDGTVGIALNLEADNVGAVLMGSGLSIQEGSAVKATGKIAQVPVGEAFLGRVVNALARPIDGKGDIASKESRLLEGPAPGIIERRSVYEPMQTGLIAIDAMIPIGRGQRELIIGDRQTGKTAIATDAIVNQKGSGVICVYVAIGQKASSVAQIVTTLQEKDAMRYTIIVSETADSPATLQYLAPYTGAALAEYFMYSGRHTLVIYDDLSKQAQAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDALGEGSMTALPVIETQGGDVSAYIPTNVISITDGQIFLSADIFNAGIRPAINVGISVSRVGSAAQVKAMKQVASKLKLELAQFSELEAFAQFSSDLDAATQAQLARGVRLRELLKQAQSEPLSVADQVATIYTGTNGYLDDLAPTQVRAFLSALRSYLATSKPKYAQIMAANVFTPEAESLVKEAIAETKASFK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MDM10_SCHPO
Sequence: MMSFNDYIFYEYLKKTNWNIHNLYCNLTQTADNILNFEIPSGVSCQLSSLTSSNFASGCKISAMPILNGSMSYVYTNVNLENLNRNITYNLQHFYEGYKHVDVPFVHYVNEFQDKKLPLRPTLLYGRMHLPSQHLDAIFATRLSPWLLFFIQGVNEIEDGVGDNLCFNWQYDTGKRCLEFVYESSGAMLGVRGLWNLNYRELNTKINMENKAPSNMRWSLGFETYYGVLTKCAGASLGMRLHSGPSHPYAPFILTCTLNPIVGHITSTFSTAEPRTKAFSAQYDFNIYSYESQLKLGIELWRSKQEMSQSTNDPTANSMSSLLKGTCSTSGDVSISWQARIRNFLLTIGTEAQLTKIDPLFFGVHFEYSK
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component mdm10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: MRPG_BACSU
Sequence: MIETAKVVVAVFILLGALICLIASFGVLRLPDVFTRAHAASKGSTLGVNMILLGVFFYLWFVTGELSAKILLGILFIFITSPIGGHLICRAAYNSGVKLDERSVQDDYNGIRNFVIKRKEDSYL
What is the function of this protein?
Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis.  Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB.  MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance.  MrpA is required for initiation of sporulation when external Na(+) concentration increases.  Also transports Li(+) but not K(+), Ca(2+) or Mg(2+).
What are the official names of this protein?
Na(+)/H(+) antiporter subunit G, Mrp complex subunit G, Multiple resistance and pH homeostasis protein G.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: F163B_MOUSE
Sequence: MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEDEEEPDFAVHSHLPPLHSNRNLVLTNGPALYPAATTSFSQKSPQARALCRSCSHYEPPTFFLQEPEDEDFEGVRNGGGRVAYKSISQEDVELPSASFGGLQALNPNRLSAMREAFSRSRSVSTDV
What are the official names of this protein?
Protein FAM163B.
What is the protein family that this protein belongs to?
Belongs to the FAM163 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LYSRA_THEMA
Sequence: MVYPRLLINLKEIEENARKVVEMASRRGIEIVGVTKVTLGDPRFAETLRKAGIGILGESRIRNVLRMKKAGIEGPFMLLRLPMMSELVEDVKHFDYIMVSDPDVAKKVDELSREMKRNVKIIYMIDVGDLREGVWFEKAVEEIAQCRGANIVGIGTNFGCYGGIIPTREKFEILLDIKEKLEKNHGFNIEIVSGGNTPALYALENGEIPEGINQLRIGEAIVLGRDITNNRVIDWLSQNTFLIEAEVIEVKEKPSVPLGKRGLDVFGRKVDFVDRGIRKRAICALGEQDIDSRGLIPVDKGVEVLHASSDHIVLDVTDFGDVKVGDVFRFRMTYSCLLKAMTSPFVEKVYEPSI
What is the function of this protein?
Catalyzes the interconversion of D-lysine and L-lysine.  Has also high activity toward ornithine, and weaker activity toward alanine.  Contributes to production of D-lysine and D-alanine for use as peptidoglycan components.
What are the official names of this protein?
Lysine racemase, Lys racemase, Ornithine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.