PharMolix/UniProtQA huggingface dataset:
Protein: YL116_MIMIV
Sequence: MDSLYKWFSTIYQGKDTCIDQDVFLSTEIQSIEIQPEEKPSEEKQPEEKSSEEKPKLQPVSAINSEKTQKPISSVALPNEDFNKLLYNFPSLSRRPQPKTTTERPQPKTTMDDKQVVVTFITERGRSCELSSERSRYRSPERSRYRSPERSRYRSPERSRYRSPERSRYRSPERSRYRSPERSHYRSPDRSHYRSHNKSTERSHYRSTERSRYRSPERSHYRSPEISRKRSRDESREKSLGRSRKMSRDESREKSLNESHKRSRDESQEKSYEPRPAKKLREKSPDEHQEKHQEKSPEKQVEITKPLEDYIALPKENVPDVFEIEKSQSTRYFSEKARIYFKNTHDGSIVWYKDDAIHRDGDLPAVIESDGTVKYYRDGKIHREGDKPAIIIPGKGKSWYLDGKLHRDGDEPAYVSNDGTLKWYRHGLLHRENDNPAIINLDGSMVWYVDGKLHRGGDLPAIIKPGICFKWYVNGHVHRDNDLPAIINIFKMPKLCNMYRIGDMVWYQHGQRHRSGGKPAIVTFRGVLFYFENGRRIYESPNGKEYYNMTANKLMMDFPYLLE
What are the official names of this protein?
Uncharacterized protein L116.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L41 family.
Protein: YEI1_SCHPO
Sequence: MSLDKQIPIIYDFGENYEKNKDIWRRQCIYQILTDRFALDDHCTTAPSTGRMYLGGTWRGIIQKLDYIQSLGCTAVWISPIVKNIEGVTGYGEAYHGYWAEDLTQLNPHFGTKQDLTELVDQLHKRNMLCMIDIVVNHMAHAGDSPIDYSKYAPFNSPSHYHPKRFLHNYDDTWDCEIAWLGDEVVSLMDIRTEDQEVHNFFQNWIRDLIQTYHFDGLRIDTAKHVQKEFYPPFIAAANVFAFGEVYHGDPKFIAKYLEYIPSAANYPLYYQIENTFFPPKQSMNIFYQKAILEARATSMDTTILGNFTENHDVPRFLNRSTDYSLLCNTLTLLLFTDGIPIIFQGQEQMYAGGHDPENRDALWTSNYNQQNPIFQFLKKLIKLRQFLVDNVSGFTTELSNMLFVNEHVYVFRRPGVIIVVSNAGSNSDVDTSAEFSITERESLEFIDVLSGSQFSSLPTEDSSTISMNLEFSFPRVLVHRGLFHSMNELA
What are the official names of this protein?
Uncharacterized glycosyl hydrolase C27E2.01.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UFM1_ARATH
Sequence: MATGGKVSFKVTLTSDPKLPFKVFSVPEGAPFTAVLKFAAEEFKVPPQTSAIITNDGIGINPQQSAGNVFLKHGSELRLIPRDRVGAVFVMDP
What is the function of this protein?
Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins.
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
Protein: END3_KLULA
Sequence: MPKLEQFEIKKYWQIFSGLKPVENKLTHDQVLPILFNSKLDTSILNKIWFLADIDDDDQLDFEEFVICMRMIFDMVNKNIDSVPDELPDWLIPGSKAELVKQRKTERSSGTAETSSVVNVPTSSPAVDDYQKEVDWYISRDDKSQYESIYESAITSRDNSVSYVSLSSAVRSKYINLSSQDLEKTWRLVNPKLDTSIDKDPALYFIHILRQVNDYACPIPSHLPSALKETFTKTRVSTDLSSKQSEVRRPTLSTSNSSSYQIPKRGGTDFSVTQGTDWEVVRLQRELANIDSELSSAQQQSTSHNDSNDRMKLVKQQLEQFLEYQKNLVNNSNTSSESVDVGGLRDDIESIEQQVQMLEEYLKTKKSELHNLKIEVQSLY
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein END3, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: EFG_TRIL1
Sequence: MSRLSPLDKYRNIGIMAHIDAGKTTTTERILYYTGVSHKIGEVHEGTATMDWMEQEQERGITITSAATTCEWNDHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFCSVGGVEPQSETVWRQADKYRVPRIAFINKMDRIGADFFRGVQMIKDRLKANPVPLQLPVGKEDYFKGIVDLVRMKAIIWDEESLGAKFHEEEIPADLLDEAKEWRDKLIEEISSHDDALMEKYLGGEELTEAEIMAAIRSCTINIQIIPVVCGSSFKNKGVQNLLDAVVDYMPSPLDIPAIKGIDESGAEVERKADDTEPFSALGFKIMTDPFVGQLTFIRVYSGVLQSGSYVYNATKGKRERIGRLLKMHANKREEIKEVYAGDIAAAVGLKYTTTGDTLCNEDQAVILESIEFPEPVISIAIEPKTKSDQEKLGLSLQKLASEDPSFRVKTDEETGQTIISGMGELHLEIIVDRMMREFKVEANVGKPQVAYRETITKKVKVEGKFVRQSGGRGQYGHVWLEVEPQPEPGKGYEFVDAIKGGVVPREYIPAVDKGIQEATDNGVLAGFPVVDVKVTLIDGSYHEVDSSEMAFKIAGSMGFKEGCQKAGPILLEPIMSVEVVVPEEYMGEVIGDLNSRRGRIMGMDSRAGAQVVSSMVPLANMFGYSTDLRSATQGRATYAMTFDHYEPVPKSVSDEIIAKVKG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPX_HELPJ
Sequence: MQKVTFKEETYQLEGKALKVGDKAPDVKLVNGDLQEVNLLKQGVRFQVVSALPSLTGSVCLLQAKHFNEQAGKLPSVSFSVISMDLPFSQGQICGAEGIKDLRILSDFRYKAFGENYGVLLGKGSLQGLLARSVFVLDDKGVVIYKEIVQNILEEPNYEALLKVLK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: ARAA_CITK8
Sequence: MTIFDNYEVWFVIGSQHLYGSETLRQVTQHAEHVVKALNTEAKLPCKLVLKPLGTSPDEITAICRDASYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKHAHARIGSWMRQAVSRQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNAVSDGDINALVDEYESHYTLTPATQIHGDKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSGGLPGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDAPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHDLPKLPVANALWKAQPDLTIASEAWILAGGAHHTVFSHALDLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFKR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: SYNC_HUMAN
Sequence: MVLAELYVSDREGSDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLINEESDVDVQLNNRHMMIRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPRFVQRCTP
What is the function of this protein?
Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn) (PubMed:9421509, PubMed:32738225, PubMed:32788587).  In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells (PubMed:30171954, PubMed:12235211).  Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells (PubMed:32788587).
What are the official names of this protein?
Asparagine--tRNA ligase, cytoplasmic, Asparaginyl-tRNA synthetase, AsnRS, Asparaginyl-tRNA synthetase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_MARMM
Sequence: MLTSDLSNDLANPLPLAQALIRRPSVTPIDAGALDVMQAALEQLGFTCRRYPFGEVDNLYARRGTASPCFLFAGHTDVVPPGDDDAWRKPPFGAEAEDGVLWGRGAADMKGAIAAMVASVQRFLDTGEPKGSIAFLITGDEEGPAIHGTKAVLEALADEGETFDHCLVGEPTNPNVLGDTIKSGRRGSLNCTLTVTGRQGHVAYPERAENPIPALLDLLGRLLARKLDDGVPPFQPSNLEVTSVDVGNPTTNVIPAAATARFNIRFNIAHNGDALSDWIRSEVAKIDLDFDGRIEADIHVTGEAFLTPAGPFTTLLQDCVEAETGRRPALTTGGGTSDARFIQLYAPVAEFGLVGATMHQVDERVPVSDIETLTAIYTRILKGYFKDFPA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CAIA_SALPC
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQVLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_NAUPA
Sequence: MARYTGPVEKIERRLGVSLELKGERRLAGKSALDKRPYAPGQHGQRRTKISEYGLQLREKQKIKFYYGVLEKQFRKFFREANRQEGNTGENLIKLLERRLDNVVYRMGFASTRRFARQLVTHGHILVNGKKVNIPSYLVKEGDRIEIREKSKNNVQIQRALELSQQTGIAPWVDVDKEKLVGVFQRVPEREEVNIPVEERLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: NUDI_ECO57
Sequence: MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLAHYDLNVATRKTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: Y1532_STAAN
Sequence: MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
What are the official names of this protein?
Putative universal stress protein SA1532.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_ALKEH
Sequence: MSWSRHWPAPAKINLFLHILGRRPDGYHRLQTAFQILDRGDELAFRVRPDGELRRRGGLDHVPPDQDLTVRAARLLQQTTGCRLGADIVLDKRLPDGGGLGGGSSNAATVLQALNRLWGTGLSTLELAGLGLRLGADVPVFVHGRTAWAEGVGERLTPIETPSRWFLVVHPGCRVSTAEVFAAEGLTRDSAPSTISALRAGRVRNDCEPWVRAHYRAVDEALGWLSRFAPARMTGTGACVFAPFEREAQARAALDRLPAAWQGFVAQGVACSSLLGRLRGEQDSADRDGPT
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SYDND_MYCGI
Sequence: MLRTRTAGSLRPADAGQTVTLAGWVARRRDHGGVIFIDLRDASGVSQVVFRDGAVLEQAHRLRSEFCVAVTGVVEIRPEGNANADIPTGEVEVNATSLTVLGESAALPFQLDETAGEEARLKYRYLDLRREVPGNAIRLRSKVNAAARGVLAGHDFVEIETPTLTRSTPEGARDFLVPARLQPGSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDMEMSFVDADDVMALSEEVLRAVWATIGYDLPLPLPRISYADAMRRFGSDKPDLRFGLELVECTEYFADTPFRVFQAPYVGAVVMPGGASQPRRTLDGWQEFAKQRGHKGLAYVLVGKDGELTGPVAKNLTDAERAGLTAHVGANPGDCVFFAAGTAKSARALLGATRIEVAKRLDLIDPDAWAFTWVVDWPMFESAAEATASGDVAVGSGAWTAMHHAFTAPTPESEATFDTDPGSALSNAYDIVCNGNEIGGGSLRIHRRDVQERVFAMMGISQEEAEDKFGFLLEAFTFGAPPHGGIAFGWDRIVALLAGLDSIREVIAFPKSGGGVDPLTEAPAPITAQQRKESGIDAKPGKDGA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYSP_RHIMP
Sequence: MSSRSSKYMYKSSGGAGDISIEYGTDLGALTRLEDKLRLLQEDLESERELRQRIEREKSDLTVQLMQLSDRLEEAEGSSETVVEMNKKRDTELSKLRKLLEDVHLESEETAHHLRKKHQEAVAEMQEQMDLMTKAKSKAEKERQKFQAEVYELLAQVENTNKEKITIQKTVEKLEHTVYELNIRIEELNRTVTEVTAQRTRLSAENAEYLKEVHELKVSLDNVNHLKSQLATQLEDTRRRLEDEERKRASLESSMHTLEVEIESLKVQLEEESEARLEVERQLVKANADAAAYKTKYETEVQAHADEVEELRRKMAQKISEYEEQLEALLTRCSNLEKQKSRLQSEVEVLIMDLEKATAHAQNLEKRVAQLEKLNIDLKSKVEELTILLEQSQRELRQKVAEIQKLQHEYEKMREQRDALQRENKKLVDDLSEAKSQLADAIRRLHEYELEIKRLENERDELAAAYKEAETLRKQEEAKCQRLTAELAQVRHEYERRLQIKEEEIEALRKQYQLEVEQLNMRLAEAEAKLKTEIARIKKKYQAQITELEMSLDAANKQNMDLQKIIKKQAIQITELQAHYDEVHRQLQQCADQLAISQRRCQGLQAELDEQRVALESALRSKRAAEQSLEESQARVNELTTINVNIAAAKNKLESELSALQADYDELHKELRVVDERCQRTIVELKSTKDILVEEQERYIKVESIKKSLEVEVRNLQVRLEEVEANALAGGKRVIAKLEARIRDVEIELEEEKKRHAETQKILRKKDHRAKELLLQTEEDHKTITMLNDAVEKLNEKVKVYKRQLNEQEGLSQQNLTRVRRFQRELEAAEDRADSAESNLSLIRAKHRSWVTTSQVPGGTRQVFVTEESSQNF
What is the function of this protein?
Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.
What are the official names of this protein?
Paramyosin.
What is the protein family that this protein belongs to?
Belongs to the paramyosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: RL9_STAA8
Sequence: MKVIFTQDVKGKGKGKKGEVKEVPVGYANNFLLKKNYAVEATPGNLKQLELQKKRAKQERQQEIEDAKALKETLSNIEVEVSAKTGEGGKLFGSVSTKQIAEALKAQHDIKIDKRKMDLPNGIHSLGYTNVPVKLDKEVEGTIRVHTVEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: COX2_APIKO
Sequence: MSTWMMFMFQESNSFYADNLVSFHNLVMMIIIMISTLTIYIIFDLFMNKFSNLFLLKNHNIEIIWTIVPIVILLIICFPSLKILYLIDEIINPFFSIKSIGHQWYWSYEYPEFNNIEFDSYMLNYSNLNQFRLLETDNRMIIPMKIPMRLITTSTDVIHSWTVPSLGIKVDAVPGRINQLNLISKRPGIFFGQCSEICGMNHSFMPIMVESTSFKFFLNWINKQN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNLJ_LARHH
Sequence: MTDLNPTARAAGLRALLHRYNHEYYVLDAPSVPDAEYDRLFRELEALEAAHPELASADSPTRRVGGAPLAAFASVTHRLPMLSLNNVFSDMQDSDPAGRHAELAAFDQRVRDGLGLDEVEYAVEPKFDGLAVSLVYEHGVLVQGATRGDGETGENVTENLRTVRSIPLRLENAPGDDLFAPAVVPARLEVRGEVLMLKRDFERLNSEQDAAGLKRFANPRNAAAGSLRQLDSRITASRRLTFFAYAVAEADGVSLPATHSATMDWLAGLGLPVSRQRSVVRGLAGLTGAYEAMLAQRAGLPFDIDGVVYKVNRLSEQARLGFVSRAPRFAVAHKFPAEEALTVVEDITVQVGRTGAITPVARLQPVFVGGVTVTNATLHNEDEVRRKDVHVGDTVIVRRAGDVIPEVVSVLAERRPPQARAFEMPLVCPVCGSHIVREADEAVARCSGGLYCSAQHKQALQHFASRKALDVEGLGEKLVDQLVDAGLVHTPADLFALDQPALARLERMGDKSAENLVRALDACRHTTLARFVYALGIRNVGEATARDLARHFGTLDALMAADQDMLMTAPDVGPIVARSIVDFFAEAHNREVVDALLAAGVSWPVVETVTSAGVAGVSGKTFVLTGTLPTLGRDDAKARIEAAGGKVTGSVSKKTHYVVAGEAAGSKLDKAHELGITVLDEAALLALLAGNA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NRDR_ECO7I
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL18A_METKA
Sequence: MSEVKVFEVRGTFRMGDEPRQPFTRQVPATSEEEALEKVYSDLGSEHGVSRMEIQIEEIREIDPSKVEDPILRRLLGVEE
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: FLGH_AZOSB
Sequence: MKALALLAVLLLSGCASIYSTPPTAIHQPMSARPDMRAQAVPATGSIYQPSQARPLFEDRRARNVGDIITINLVERNTAQKSANASATRGSAITGGISLTAPNIASLANAKLNGLQADVGLDSDFSGEGAAAANNVFNGTISVTVIDVYPNGNLLVSGEKMVAINQGNEFIRFSGVINPTTVTAANTVQSTQVADARIEYRGSGFIDESNTMGWLQRFFVAIAPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: RL24_RENSM
Sequence: MGKINIKKGDLVQVITGAKAERGGDRGKQGKVLRVFTESNRVLVEGINRVTKHTKVGQSQRGSKTGGIEIVEAPIHISNVALVDPSTKKTTRVGYRLETVERDGRERVTRVRFAKSSGKDLA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: HTX2_CYRLI
Sequence: ACKGLFVTCTPGKDECCPNHVCSSKHKWCKYKI
What is the function of this protein?
Spider venom neurotoxin that blocks voltage-gated sodium channel Nav1. 3/SCN3A in human (IC(50)=80 nM) and rat (IC(50)=160 nM).  Partially inhibits human Kv11. 1/KCNH2/ERG (25% at 175 uM).
What are the official names of this protein?
Beta/kappa-theraphotoxin-Hlv1a, Beta/kappa-TRTX-Hlv1a, Beta/kappa-theraphotoxin-Hl2a, Beta/kappa-TRTX-Hl2a, Haplotoxin-2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 11 (haplotoxin-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL32_STAA8
Sequence: MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGREYKLSHRVCKNCGSYNGEEVAAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: VP35_FOWPN
Sequence: MAPGDKKQIIFVITTIGRPSSTVVPFKNLEVSEWSYKKGIKNGYDDYRDPPSPKPLPKSKQEPNADDKVGDIEYDEMVSVRDGYYSDVCRLTCTEDTKIFIADHISLWRYIMDNAEKLPNYVVIMEDDNTITGEGFITNLDNITKVLNDNNVDILQLVTHTKLLKDRNSQHLMLLPDLEAFKGSFDVSLSAYIIRQEAVRKLYSYFTNNKPSFDISLEILRIENTLGITRYVVDNDRYVYHDYKLANEFMKNKKNRLSIKSRIDGWIMDNWPSFYHRMYYPLFSVFGKYDITMMFLIAIVIIIGLAIFDINNKLLWLLSGVFLAYSM
What is the function of this protein?
Envelope protein that binds to the cell surface to provide virion attachment to target cell.
What are the official names of this protein?
Immunodominant envelope protein p35, Ag35, Virion envelope protein p35.
What is the protein family that this protein belongs to?
Belongs to the poxviruses protein p35 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: PSBA_OLTVI
Sequence: MTAILERREATSRWAQFCNWITSTENRLYIGWFGVIMIPCLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAVIPTSNAIGLHFYPIWEAASLDEWLYNGGPYQLIVCHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGLSTMAFNLNGLNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLASVEAPSVNA
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NOGG_MOUSE
Sequence: MERCPSLGVTLYALVVVLGLRAAPAGGQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGPAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC
What is the function of this protein?
Essential for cartilage morphogenesis and joint formation.  Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (PubMed:9585504, PubMed:9603738).  Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity).
What are the official names of this protein?
Noggin.
What is the protein family that this protein belongs to?
Belongs to the noggin family.
What are the subcellular locations of this protein?
Secreted.