PharMolix/UniProtQA huggingface dataset:
Protein: COX3_DASNO
Sequence: MTHQTHAYHTVNPSPWPLTGALSALLMTSGLIMWFHFNSPLLLVLGLTTNFLTMYQWWRDIIRESTFQGHHTTIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLAPTPELGGCWPPTGINPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGHRKHMLQALFITIALGVYFTLLQASEYYEAPFTISDGIYGSTFFVATGFHGLHVIIGSSFLIVCFMRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HTPG_BUCBP
Sequence: MTANKNQKKTYNFKSETKELLHLMIHSLYSNREIFFRELISNAADAIDKLKFNAISAPELYENDTNLYIRIFSNKNNNSLTISDNGIGMKYEDIINNLGTIAKSGTKEFIKTLNKNNKIKNDLIGQFGVGFYSSFIVSEKVIVKTRFAGLKENQGVIWTSDGKGTYEVNEINKKERGTEVTLYLTKDHYEFLETWKIQNTVSKYSDHISIPIELNTYDEKEKTYFWKQINQAEAIWTRPKSEITELQYKNFYKKIANDTNDPLTWTHNKVEGNQEYTILLFIPSKSAWDIWNRDNKHGLKLYVKRVYIMDDAEQFLPNYLRFVKGIIDSNDLPLNVSREILQDHKLVYNLKKSLTKKVLQVLHSLSQNVSKYEIFWKQFGLILKEGPAEDSENRTSISNLIRFSSLLNNTQKPTMSLENYVKNMKQNQEKIYFITADNYASAVSSPHLEFFKKKNIDVLILSDKIDEWMMNYLIEYNEKKFQSVSKDDKSIEKLVHEQNSQNETYQENMNDFLNRAKKTLSDKIKDIRFTHKLTNTPAMVITDSNEMSTQMAKLFSAAGQTVPTIKYILEINPNHLLIKKINNEKNEKKFKNWINFLFEQCLLAEKNTLDNPNKFIARINDLLINN
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSD3_ARATH
Sequence: MDILTTILNLLLPPLTIIFLFLFYPFYLLIKLVLCLRKNLHFENVARKVVLITGASSGIGEHVAYEYAKKGAYLALVARRRDRLEIVAETSRQLGSGNVIIIPGDVSNVEDCKKFIDETIRHFGKLDHLINNAGVFQTVLFEDFTQIQDANPIMDINFWGTTYITYFAIPHLRKSKGKIVAITSGSANIPLPLASIYAASKAALLRFFETLRIELSPDIKITIVLPGVVSTDMTTPHCIEKYGSDFILSESVSKCAKAIFRGIGRGETYIEEPSWMKWLFIMKNVCPEIVDYGLNYLFVSYLKPYFKRD
What are the official names of this protein?
11-beta-hydroxysteroid dehydrogenase-like 3, 17-beta-hydroxysteroid dehydrogenase-like 3, Hydroxysteroid dehydrogenase 3, AtHSD3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL21_ACICJ
Sequence: MFAVIRTGGKQYRVVPDAVLKVEKLEAEAGSTVTFTDVLAIGGEQGVTLGKPVVEGATVTATVIAQDKLDTVIIFKKRRRQNSRRKNGHRQPVTVLRVSGINAA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PPSA_PYRAB
Sequence: MAYRFIKWFEELRKEDVPLVGGKGANLGEMTNAGIPVPPGFCVTAEAYKYFVENVKISKEDVKRILGEKANKGTIAEVLAQAPDEPRPLQEWIMDIINRTNVDDSKQLQENTAVIRELIKSLDMPAEIADEIKQAYKELSQRFGKDEIYVAVRSSATAEDLPEASFAGQQETYLDVLGADDVIDKVKRCWASLWTARATFYRAKQGFDHSKVYLSAVVQKMVNSEKSGVMFTANPVTNNRNEIMINASWGLGEAVVSGAVTPDEYIVEKGTWKIKEKVIAKKEVMVIRNPETGKGTVTVKVAEYLGPEWVEKQVLTDEQIIEVAKMGQKIEEHYGWPQDIEWAYDKDDGKLYIVQSRPVTTLKETTTEEVEEVEEAEVILKGLGASPGIGAGRVVVIFDASEIDKVKEGDVLVTTMTNPDMVPAMKRAAAIITDEGGRTSHAAIVSRELGIPAVVGTKEATKKLKTGDYVTVDGTRGLVYKGIVKSLVEKKKKEEAAAAPGAAVAAAPLVTGTLVKVNVSMPEVAERAAATGADGVGLLRAEHMILSIGQHPVKFIKEGKEEELVEKLAEGIEKVAAAFYPRPVWYRTLDAPTNEFREMPGGEDEPEERNPMLGWRGIRRGLDQPELLRAEFKAIKKVVEKGYNNIGVMLPLVSHPEQIRKAKEIARSVGLEPHKDVAWGIMIEVPAAAIIIEDLIKEGIDFVSFGTNDLTQYTLAIDRDNERVAKLYDETHPAVLKLIKHVIKVCKRYGVETSICGQAGSDPKMARILVRLGIDSISANPDAVQLIRQVVAQEERKLMLEAARKRLFEEEEEEEEFLF
What is the function of this protein?
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
What are the official names of this protein?
Probable phosphoenolpyruvate synthase, PEP synthase, Pyruvate, water dikinase.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: Y162_LIGS1
Sequence: MDTAQILETIKMISEENLDIRTITMGISLLDCIDSDSDKACQKIYDKITTKAKDLVKVGNQIATEYGIPVINKRVSVTPISLIAAASKDKDYVKYAKALDKAAQTLGIDFIGGYSALVQKGYQNGDRTLIKSLPQALAETNLVCASVNVGSTRSGINMDAVKEMGQVVKSASELDFMTNAKMVIFCNAVEDNPFMAGGFHGVGEPDAVINVGVSGPGVVKSALEKVKGASMDVVAETIKQTAFKVTRMGQLVGSIAAEKLNVPFGIVDLSLAPTPAVGDSVAQILEEIGLEQVGTHGTTAALAMLNDAVKKGGIMACSHVGGLSGAFIPVSEDAGMIDAVNAGSLNIEKLEAMTVVCSVGLDMIAIPGDTPAETISAMIADEAAIGMINNKTTAVRVVPVPGKDVGETVEFGGLLGHAPIMAVNKVSSADMINRGGLIPAPVHSFKN
What are the official names of this protein?
UPF0210 protein LSL_0162.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RAC2_HUMAN
Sequence: MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL
What is the function of this protein?
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state.  In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization.  Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
What are the official names of this protein?
Ras-related C3 botulinum toxin substrate 2, GX, Small G protein, p21-Rac2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Membrane-associated when activated.
Protein: RS3A_CANGA
Sequence: MAVGKNKRLSKGKKGLKKKVVDPFTRKEWYDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGSEDHSFRKVKLRVDDVQGKNLLTNFHGMDFTADKLRSMVRKWQTLIEANVTVKTSDEYIIRVFAIAFTRKQSNQVKRTAYAQSSHIRAIRKVISDILTREVSNSTLAQFTSKLIPEVINKEIENATKDIFPLQNVHIRKVKLLKQPKFDLGSLMALHGEGSAEEKGKKVSGFKDEVLETV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AL1A1_HORSE
Sequence: MSSSGTPDLPVLLTDLKFQYTKIFINNEWHDSVSGKKFPVFNPATEEKLCEVEEGDKEDVNKAVAAARQAFQIGSPWRTMDASERGRLLYKLADLVERDRLILATMESMNGGKLFSNAYLMDLGGCLKTLRYCAGWADKIQGRTIPSDGNFFTYTRHEPVGVCGQILPWNFPLLMFLWKIAPALSCGNTVVVKPAEQTPLSALHVATLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPFIVFADADLETALEVTHQALFYHQGQCCVAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVSDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTTYGLFAGSFTKDLDKAITVSAALQAGTVWVNCYGVVSAQCPFGGFKMSGNGREMGEYGFHEYTEVKTVTVKISQKNS
What is the function of this protein?
Cytosolic dehydrogenase that catalyzes the irreversible oxidation of a wide range of aldehydes to their corresponding carboxylic acid (By similarity).  Functions downstream of retinol dehydrogenases and catalyzes the oxidation of retinaldehyde into retinoic acid, the second step in the oxidation of retinol/vitamin A into retinoic acid.  This pathway is crucial to control the levels of retinol and retinoic acid, two important molecules which excess can be teratogenic and cytotoxic (By similarity).  Also oxidizes aldehydes resulting from lipid peroxidation like (E)-4-hydroxynon-2-enal/HNE, malonaldehyde and hexanal that form protein adducts and are highly cytotoxic.  By participating for instance to the clearance of (E)-4-hydroxynon-2-enal/HNE in the lens epithelium prevents the formation of HNE-protein adducts and lens opacification.  Functions also downstream of fructosamine-3-kinase in the fructosamine degradation pathway by catalyzing the oxidation of 3-deoxyglucosone, the carbohydrate product of fructosamine 3-phosphate decomposition, which is itself a potent glycating agent that may react with lysine and arginine side-chains of proteins (By similarity).  Has also an aminobutyraldehyde dehydrogenase activity and is probably part of an alternative pathway for the biosynthesis of GABA/4-aminobutanoate in midbrain, thereby playing a role in GABAergic synaptic transmission (By similarity).
What are the official names of this protein?
Aldehyde dehydrogenase 1A1, 3-deoxyglucosone dehydrogenase, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, Retinal dehydrogenase 1, RALDH 1, RalDH1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, axon.
Protein: GPDA_YERPY
Sequence: MNTNPASMAVIGAGSYGTALAITLARNGHQVVLWGHDPKHIQQLQQDRCNRAFLPDAAFPDTLRLETDLACALAASRDVLVVVPSHVFGAVLHQLKPHLRKDARIVWATKGLEAETGRLLQDVAREVLGEAIPLAVISGPTFAKELAAGLPTAIALASTDVQFSEDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMTRLGTALGADPSTFMGMAGLGDLVLTCTDNQSRNRRFGIMLGQGLGVKEAQDNIGQVVEGYRNTKEVLALAQRHGVEMPITEQIYQVLYCHKNAREAALTLLGRTKKDEKIGI
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_BURL3
Sequence: MNPPKSAPDAQGLSYRDAGVDIDAGDALIDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYKEPVLVSGTDGVGTKLKLAFHLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVDTAATVVKGIAQGCELSGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSKIIDGSTIAEGDVVLGLASSGIHSNGFSLVRKIIERANPDLSADFHGRSLADALMAPTRIYVKPLLALMQKLTVKGMAHITGGGLVENIPRVLREGLTAELDQDAWPLPPLFKWLQEHGGVADAEMHRVFNCGIGMAVIVSAADADAAIADLTAAGEQVWKIGTVRATREGEAQTVVV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_RHOCS
Sequence: MAEPDIKSFERRMDGAVETLRKEFGGLRTGRASTTLLDPVYVDAYGSSSPLNQVATVGVPEPRLITVQVWDRSLVKAVEKAIREAGLGLNPQSDGQTLRVPIPELNQERRQELAKVAAKYAEQARVAVRNVRRDGMDMLKKLLKDGDISEDEQKTWADKVQALTDAHIKKIDEALATKEKEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAPQ_RHIL3
Sequence: MTHEAVDTTPLHGTGWSFRSAMYDPKYRSIFYQILTIVILVGFVWWVAHNTAVNLARSNTASGFGFLRGRAGFEIGQSLITFSSDSTYARALLVGILNTLLVAVTGIFTATIIGFLIGIGRLSRNWLIAKLCTVYVEVFRNIPPLLVIFFWYLGVLSVLPQPRESVGLPFSMYLNNRGLAFPKPIFDTGMIAVGIALVIAIVASIIIARWAHKRQAATGQPFHTVWTAIALIVGLPLLVFVVSGFPLTFDVPVAGKFNLTGGSVVGPEFMSLFLALSFYTASFIAEIVRGGIRGVPKGQSEAAGALGLHPSSVTRLVVVPQALRIIIPPLTSQYLNLTKNSSLAIAIGFSDLVAVGGTILNQSGQAIEIVCIWGIVYLSLSILTSLFMNWFNAKMALVER
What is the function of this protein?
Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
General L-amino acid transport system permease protein AapQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VGRG2_VIBCH
Sequence: MATLAYSIEVEGLEDETLVVRGFHGQESLSNSVFLGQACYGFRYQMQLASRVSNLTADQMVDKRAELKLYRNSQLVQRVHGIVRAFSQGDIGHHHTFYQLTLVPALERLSLRHNSRIFQKQTVPEILSILLQEMGIHDYAFALKRDCVQREFCVQYRESDIDFLHRLAAEEGLVYSFVHEAGKHTLYFSDASDSLSKLPEPIPYNALAGGTMDTPYIHGLTYRTQAEVSEVQLKDYSFKKPAYSFLQTVQGTELDYQQTRYQHFDAPGRYKDDVNGAAFSQIRLDYLRRHAHTATGQSNEPLLRAGYKFDLQEHLDPAMNRDWVVVSINHQGEQPQALQEEGGSGATTYNNQFSLIPGHLHWRAEPQPKPQVDGPMIATVVGPEGEEIFCDEHGRVKIHFPWDRYSNGNEQSSCWVRVSQGWAGSQYGFIAIPRIGHEVIVSFLNGDPDQPIITGRTYHATNTPPYTLPEHKTKTVLRTETHQGEGFNELSFEDQAGKEQIYLHAQKDFDGLIENDHTTVIRHDQHLTVENDQFTQIKHNQHLTVEGESRTLVKLDCSSEIGGSLQQKIGSKAIYDAGTEVHLKAGNKLVLEAGNELTIKAGGSFIKVDAGGVHVVGSAINLNSGGSAGSGSGYGGKMAELPQGVDKAKTPQEIELAAVTPTQQSMSPLLKARQIEALKGPAPVCEVCEEAKGN
What is the function of this protein?
Part of the type VI secretion system specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection (PubMed:21555399).  Forms the spike at the tip of the elongating tube formed by haemolysin co-regulated protein Hcp.  Allows the delivery of the VasX antibacterial toxin to target cells where it exerts its toxicity (PubMed:21555399).
What are the official names of this protein?
Type VI secretion system spike protein VgrG2.
What is the protein family that this protein belongs to?
Belongs to the VgrG protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PAGP_EDWTF
Sequence: MKTHNDILAALAALPLFLTGAAFAAEPGMLDTLRNNIVQTWEQPQHYDLYLPAITWHARFAYSQEKIDSYNERPWGAGFGQSRWDEKGNWHGLYLMAFKDSFNKWEPIGGYGWEATWRPLEGSDFHWGAGYTVGVTMRDNWRYIPIPVILPMASVGYGPLTLQMTYIPGTYDNGNVYFAWLRLQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS11_THEGJ
Sequence: MSEEGQVNLKKKEKWGVAHIYSSYNNTIIHITDITGAETVSRWSGGMVVKADRDEPSPYAAMIAARRAAEEAMEKGFVGVHIKVRAPGGSKSKSPGPGAQAAIRALARAGLRIGRVEDVTPIPHDGTRPKGGRRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: EXLA3_ARATH
Sequence: MRSFLYLIVVIFLFSSSVNACDRCLHRSKASYFSSASALSSGACAYGPMATSFFAGHIAAAIPSIYKDGAGCGACFQVRCKNPKLCNSKGTIVMVTDLNTSNQTDLVLSSRAFRAMAKPVVGVDKYLLKQGIVDVEYQRVPCNYGKRNLNVRVEEASKKPNYLAIKLLYQGGQTEVVGIDIAPVGSSQWSYMSRSHGAVWATDKVPTGALQFKFTVTGGYDGKTVWSKRVLPANWNSGRIYDAGVQITDIAQEGCDTCGHIWN
What are the official names of this protein?
Expansin-like A3, At-EXPL3, AtEXLA3, AtEXPL3, Ath-ExpBeta-2.3.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin-like A subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PPIB_SCHPO
Sequence: MKLFYFSLLFTLFFGLISANRGPKVTDTVYFDLQQGDEFLGRVTIGLFGKTVPKTAENFRALATGEKGFGYEGSIFHRVIPNFMIQGGDITKGDGTGGKSIYGSRFPDENFKLSHQRPGLLSMANAGPDSNGSQFFITTVKTPWLDGHHVVFGEVLSGYDIVKKISKAETDNRDKPLEDVKIIKSGQLSQENVEDDGTDEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B, PPIase B, Cyclophilin 4, Rotamase B.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: HXB7A_DANRE
Sequence: MSSLYYANALFSKYQVASSAFSTGVFPEQTSCAFSCSSQRASGYGSASTGAPVSSSSSVSLPSMYTNGTSLSSHTQGMYPTAYELGAVSLNMHSSLFDHPNLPMVSAGDLCKAQSSGKEEQRGYHQNNENNLRIYPWMRSTGADRKRGRQTYSRYQTLELEKEFHFNRYLSRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKSTDRCSPAADQIGGDEEEEDDE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B7a, Hox-B7.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MFRE_WOLSU
Sequence: MQKEFAFFPGCVLSQAAIESKKSIEAIAPVLGIKLREIEGWSCCGASQAQCVDPLATLVANARNLALAEQMNLPVLTTCSTCLLMLTRAKAELDRGAKDQINSFLAKGNMSYQGTSEVTSLLWVLAQNVEELKSKVKKPLSNLKVAVFYGCHSLRPEKDLGFESSTNPTSFETIVKALGAQVVPFEKRLNCCGFHAVYPAESSAMKMTSGIINTAAKSEAHCVVTPCPLCQMQLDIYQEDAQKIAKSKERVPVLHLSQLVGLALGIPAKELGLNHNVIDATKLG
What is the function of this protein?
Membrane anchor subunit of 8-methylmenaquinol:fumarate reductase (MFR), that catalyzes the reduction of fumarate using 8-methylmenaquinol-6 as electron donor.  The complex shows no succinate oxidation activity.  Is involved in anaerobic metabolism.  SdhE likely contains the quinol/quinone binding site.
What are the official names of this protein?
8-methylmenaquinol:fumarate reductase membrane anchor subunit, MFR membrane anchor subunit.
What are the subcellular locations of this protein?
Periplasm. Cell membrane; Peripheral membrane protein; Periplasmic side. Note=Membrane association is most likely mediated via amphipathic helices.
Protein: SYGA_PSEA6
Sequence: MNKFDSKTFQGLILSLQDYWARQGCVIIQPLDMEVGAGTFHPMTFLRSIGPEPISSAYVQPCRRPTDGRYGENPNRLQHYYQFQVMLKPSPSNIQELYLGSLKELGFDPLVHDIRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIECSPVTGEITYGLERLAMYIQGVDSIYDLVWTDGPMGKVTYGDVFHQNEVEQSTYNFEYADVDALFGMFDHCEKESQKMIEAGLPLPAYEQVMKASHAFNLLDARHAISVTERQRYILRVRTLSKACAEAYYQAREKLGFPMCKKEA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBF_ILLPA
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FOSB_BACAH
Sequence: MLKGINHLCFSVSNLEDSITFYEKVLEGELLVRGRKLAYFNICGVWIALNEEIHIPRNEIHQSYTHIAFSVEQKDFERLLQRLEENDVHILQGRERDVRDCESIYFVDPDGHKFEFHSGTLQERLNYYREDKPHMTFY
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_LACPL
Sequence: MLDVHFGAGNIGRGFIGETLADNGFKITFVDVNDTLIDELNKRNGYTIELAAEGQKHIEVHDVKGINNGKDPKAVAEEIAQADMVTTAIGPKILKFIAPLIADGLKLRQANNNTTPIDIIACENMIGGSQSLKKSVYESLNEDEQAWADQNAGFPNAAVDRIVPLQKHDDPLFVSVEPFKEWVIDKSQMKNPKIQLKGVDYADDLEPYIERKLFSVNTGHATVAYTGNMKGYKTIGEAVKDDSVVDQAKHVLGETGDLLIQKWGFDPEVHHAYQKKILSRFENPYISDDIERVGRTPIRKLGFNERFIRPIRELKERGRDYSALVDTVGEMFFFNYPNDSESVKLQQLLKDEPIEQVIRETTDLKDEDLVNEIKAAYEKHLAAAK
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: TAL_PSEAE
Sequence: MTSKLEQLKQYTTVVADTGDFDAIARLKPVDATTNPSLLLKAAALPRYAEHLRQATAGSGGDAGLACDRFAVAVGKDILGVIPGRISTEVDARLSFDSEATLARAHRLIELYDEQGIDRERVLIKIASTWEGIRAAEILEREGIQTNLTLLFSFAQAVACADAGVFLISPFVGRIYDWYKKSENRDYAGAEDPGVQSVSRIYRYYKANGYKTVVMGASFRNLGQIEQLAGCDRLTISPDLLQQLADAQGELPRLLLPGEGEPRQVLDESAFRWQMNEDAMATEKLAEGIRLFARDQEKLEYQLATRH
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_BURP0
Sequence: MTKKVYVKTFGCQMNEYDSDKMVDVLNAAEGLEKTDTPEDADIILFNTCSVREKAQEKVFSDLGRVRELKEAKPDLLIGVGGCVASQEGASIVARAPYVDLVFGPQTLHRLPQMIDARRESGRAQVDITFPEIEKFDHLPPARVEGPSAFVSIMEGCSKYCSYCVVPYTRGDEVSRPLDDVLTEVAGLADQGVREVTLLGQNVNAYRGAIAAGSAEIADFATLIEYVADIPGIERIRYTTSHPKEFTQRLLDVYAKVPKLVDHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPNLSLSTDIIVGFPGETDADFDKTMALVHEMSYDTSFSFIYSPRPGTPAANLADDTPRELKLKRLQHLQATIEENVARISQSMLGKVERILVEGPSRKDPNELAGRTENNRVVNFPAPSAAHPRLIGQMIDVKINHAYPHSLRGELVLAHGDASAATH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_GEOMG
Sequence: MEFVDEKRYRKIKNGVGRAVADFNLIEEGDRIAVAVSGGKDSYTLLHILEALRRRAPVKYDLVAFTIDSGYPGFRSDVIAAHLKEHGFSHHVEATTHYDIIKEKRRPGSSYCSICARLKRGVLYTLAQQHGCNKLALGHHLDDFVETLLLNQFFVGTLKAMAPRMLADNGATTVIRPLVYVEEREIIPFARENSFPVVCCCCPVCGKADIQRKRMKELLKELERENPAVKRSLLRALANVQPRHLLDRELQRVCEVP
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.