PharMolix/UniProtQA huggingface dataset:
Protein: HUTI_CUPNH
Sequence: MTLPSVSSAPSADGVWHNCHLLPDADPAHAIRDAALVVEHGRIAWLGATADLPDAYRGAARHDAHGAWITPGLVDCHTHLVYGGQRADEFAMRLAGAGYEEIARAGGGIVSTVRATRAADEDTLFAQAAARLQPLLAEGVTAIEIKSGYGLSLEAERKQLRVARRLGEHFGISVYTTFLGAHALPPEYAGRADDYIDLVCNTMLPALAGEGLVDAVDAFCESIGFSIAQTGRVFEAAARHGVRVKLHAEQLSNLGGAALAARHRALSADHLEHLDEAGVAAMAEAGTVAVLLPGAYYFLRDTNLPPIALLRQYGVPMAISTDHNPGTSPVTSLLLMMNMACTLFRLTVPEALAGVTVHAARALGASDRHGRLEAGRVADFALWRIDSPAELAYWFGRNPVATVVRQGRVHAHEGASA
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAT_SALHS
Sequence: MSSRILTSDVIGIDVLLHDHHAVLAKSTGGAVAVFANNAPAFYAVTPARMAELLALEEKLSRPGSDVALDAQFYEEPEAAPVAIPCGKFAMYPAWQPDADFQRQAALWGVALREPVTAEELAAFIAYWQAEGKVFHHIQWQQKLARSVQISRSSNGGMPQRDINSVSEPDNHIPPGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: RPOE_SALTY
Sequence: MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSGDVPDVVQESFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIEAENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIAAIMDCPVGTVRSRIFRAREAIDNKVQPLIRR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as acid stress, heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma-E factor, RNA polymerase sigma-E factor, Sigma-24.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with the inner membrane via RseA.
Protein: RRAAH_HAHCH
Sequence: MKYVTPDLCDAYPQLVSVVEPMFQNFGAKSSFGGEIVTVKCFEDNSVVKQQVDQPGHGKVMVVDGGGSKRAALLGDMLAEKAAANGWEGIIIYGCIRDVDVIRQTDLGVQALGTHPMKTDKRGIGDLNADITFGGVTFKPGHYVYADNNGVIVSPEPLSMPQEQ
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: XIS_SACER
Sequence: MTTNVTQLAATLASLAALLAEQQPAPEPEPEPAARRLPNRVLLTVEEAAKQLGLGRTKTYALVASGEIESVRIGRLRRIPRTAIDDYAARLIAQQSAA
What is the function of this protein?
Possibly a non-classical excisionase.
What are the official names of this protein?
Probable excisionase.
What is the protein family that this protein belongs to?
To the xis proteins of bacteriophages and of plasmid pSAM2 from S.ambofaciens.
Protein: GPMA_RHOP5
Sequence: MSDRLLVLVRHGQSDWNLKNLFTGWKDPDLTEQGVAEAKAAGQKLKTQGFVFDVAFTSALTRAQHTLDLMLTELGQTGLPTTRNLALNERDYGELSGLNKDDARKKWGEEQVLIWRRSYDVPPPGGESLKDTLARTLPYYVQEILPCVLRGERTLVAAHGNSLRALIMVLEKLTPEQILKRELGTGAPVVYRLNADATVASVVDLAG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: Y131_EHRCJ
Sequence: MIDHRILEILVCPLTKDKLQYNKDTNELISQKAKLAFPIRDGIPIMLIDEARKLEP
What are the official names of this protein?
UPF0434 protein Ecaj_0131.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PURT_ECODH
Sequence: MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWKYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQNVTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: KPRS_GRABC
Sequence: MKIVACNSNRPLAEAVAAALNLPLTKASVRRFADMEVFVEIHENVRGEDVFVIQSTSYPANDNLMELLITLDALRRGSARRVTAVIPYFGYARQDRKSGPRTPISAKLVANLITEAGANRVLTMDLHAGQIQGFFDIPVDNLYAAPLFARDIAERFHGRDIMIVSPDVGGVLRARAIATRLNTDLAIIDKRRERAGVSEVMNVIGDVEGRDCILIDDICDSGGTLCNAAAALIANGAASASVYTTHGVLSGGAVARIASSPISMMTITDSILATEAVRLAQNVRQLTIAPLLAEAMRRISDESSVSSLFD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMPL_LAMBD
Sequence: MAIKGLEQAVENLSRISKTAVPGAAAMAINRVASSAISQSASQVARETKVRRKLVKERARLKRATVKNPQARIKVNRGDLPVIKLGNARVVLSRRRRRKKGQRSSLKGGGSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPLTTAFKQNIERIRRERLPKELGYALQHQLRMVIKR
What is the function of this protein?
Stabilizes the tail structure and acts as a connector between the end of tail and the portal vertex of the capsid.
What are the official names of this protein?
Tail completion protein Z, Gene product Z, GpZ, Minor tail protein Z, Tail terminator protein.
What is the protein family that this protein belongs to?
Belongs to the Lambdalikevirus tail completion protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: INX19_CAEEL
Sequence: MWRTPASTGPLRQDRQMFFHATLARSFINALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSRFLSGQCLSILHSFTKLLYSMNVVAQFLILNACLKSSDFLFFGFQVLNDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLWQEFRERNWREFEEHEEMKDVEMRRIHGGERIVISNPGQTKSFL
What is the function of this protein?
Structural component of the gap junctions that specifically coordinates left-right asymmetry in the developing nervous system.  Acts by forming gap junction network linking embryonic neurons and providing electrical coupling between cells, leading to promote or inhibit AWC signaling.  Required for the left and right AWC olfactory neurons to establish asymmetric patterns of gene expression during embryogenesis.  Acts autonomously.
What are the official names of this protein?
Innexin-19, Neuronal symmetry protein 5, Protein opu-19.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Specifically present at the transient gap junctions formed between the cell bodies of embryonic neurons. Excluded from axons and dendrites.
Protein: PLD1_MOUSE
Sequence: MSLKSETRVNTSTLQKIAADMSNLIENLDTRELHFEGEEVEYDASPGDPKAQEGCIPFSSIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTSRVPSINLYTIELTHGEFTWQVKRKFKHFQEFHRELLKYKAFIRIPIPTKRHTFRRQNVKEEPREMPSLPRSSENAIQEEQFFGRRKQLEDYLTKILKMPMYRNYHATTEFLDVSQLSFIHDLGPKGLEGMIMKRSGGHRIPGVNCCGHGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFRVKVGRKETETKYGLRIDNLSRTLILKCNSYRHARWWGGAIEEFIRKHGADFLKDHRFGSYAALHENTLAKWYVNAKGYFEDIANAMEEASEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYSKRTLMRLHPNIKVMRHPDHVSSSVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGLSLGSLTAASVESMESLSLKDKHEFHKKEPISKIVDETDMKLKGIGKSRKFSKFSLYRQLHRHHLHNADSISSIDSTSSYFSHCRSHQNLIHGLKPHLKLFHPSSESEQGLTRHSTDTGSIRSVQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIGSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQATAHELRYQVPGAVPAKVQLLRSAADWSAGIKHHEESIHAAYIHVIENSKHYIYIENQFFISCADDKVVFNKVGDRIAQRILKAHREGQRYRVYIVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGESSILEQLKPELGNKWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARDLRLECFRLVLGYLSDPSEDLQDPVSDKFFKEIWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPILAKEDALRAEEELRKIRGFLVQFPLYFLSEENLLPSVGTKEAIVPMEVWT
What is the function of this protein?
Function as phospholipase selectivefor phosphatidylcholine (PubMed:9395408).  Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.  May be involved in the regulation of perinuclear intravesicular membrane traffic (PubMed:9395408).
What are the official names of this protein?
Phospholipase D1, PLD 1, mPLD1, Choline phosphatase 1, Phosphatidylcholine-hydrolyzing phospholipase D1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Late endosome membrane; Lipid-anchor; Cytoplasmic side.
Protein: ISPG_GLOVI
Sequence: MQTLDPVTPALLPLRRVTRPVQVGALTIGGNAPVVVQSMINEDTLDTPGAVAAIRALHKAGCELVRVTVPSLAHARALERIRKTLEDTYRPVPLVADVHHDGGPIALEVARHVDKVRINPGLFVFRRARLGDYTAEDVERARAQIREELKPLVDVLGAQDKAMRIGVNHGSLSERMLYIHGDTPEGMVQSAVEFVEICEQLGYHNLVISLKASRVPVMIAVYRLAAKLLDARGMHYPFHLGVTEAGDGEYGRIKSTAGIATLLADGIGDTIRVSLTEDPLKEIPVCYGILQALGLRRTMVEYVACPSCGRTLFNLETVLHRVREATRHLTGLNIAVMGCIVNGPGEMADADYGYVGKTPGTISLYRGREEIKKVPEARGVEALVDLIKSDGRWVDP
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: STF1_HORSE
Sequence: MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTLRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPPPDYMLPPGLHVPEPKGLASGPPAGPLGDFGAPALPMAVPSTNGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGPPYGYPEPFSGGPGVPELILQLLQLEPDEDQVRARIIGCLQEPAKGRPDQPASFNLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSTLLVTGQEVELTTVAAQAGSLLHGLVLRAQELVLQMHALQLDRQEFVCLKFLILFSLDVKFLNNHSLVKDAQEKANTALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
What is the function of this protein?
Transcriptional activator.  Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues.  Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B.  Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes.  5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1.  The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity.  Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3.  Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (By similarity).
What are the official names of this protein?
Steroidogenic factor 1, SF-1, STF-1, Nuclear receptor subfamily 5 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAM_YERE8
Sequence: MQDWDPDLYRQFEAERTRPARDLLAHIPATIPQRISDLGCGPGNSTQLLHQRFPDAQLMGIDNSRAMLLSAQQRLPDCVFLEADIRQWQPAEPQDLIYANASLQWLTDHQQLFPYLFSQLAANGILAVQMPDNLDEPSHRAMREVAENGPWQQTLQEAGVVRAKVLTANQYYDLLAPHAEQVDIWRTTYYHPMPSAQAIVDWLRATGLRPFLEPLAESMRLDFLQDYLTIIDAAYPQQVDGRRLLAFPRLFIVARALK
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_ECOSE
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: TREA_SALPK
Sequence: MIPPEIRRSVLLQKAIKLALAGTLLTFASFSATAADPSSDTETPQPPDILLGPLFNDVQNAKLFPDQKTFADAIPNSDPLMILADYRMQRNQSGFDLRHFVDVNFTLPKAGEKYVPPAGQSLREHIDGLWPVLTRSTKNVEKWDSLLPLPESYVVPGGRFREIYYWDSYFTMLGLAESGHWDKVADMVANFGYEIDAWGHIPNGNRTYYLSRSQPPFFAFMVELLAQHEGDDALKEYLPQLQKEYAYWMEGVETLQPGQQNQRVVKLEDGSVLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLSTIRTTTIVPVDLNALLYQLEKTLARASAAAGDRAKASQYDALANARQKAIEMHLWNNKEGWYADYDLQNNKIRDQLTAAALFPLYVNAAAKDRAVKVAAAAQAHLLQPGGLATTSVKSGQQWDAPNGWAPLQWVAAEGLQNYGQDDVAMEVTWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPQEKPCDSVPSTRPASLSATPTKTPSAATQ
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FLHD_BORA1
Sequence: MNTTDSSLLADIREVNLSYLLLAQRMLRQDHAASMFRLGFSTEVADILMRLSPAQLVKLASSSSVLCRFRFDDYGLLSALTQDVLGGALQQAHATILLAKQPVEEIA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_STRR6
Sequence: MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYTELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTILPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGGGNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGRVAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKSISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYETGKMPEAVEEESHALSYDEVKSKMNDEK
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: CAPA_AGRIP
Sequence: MQPTMRIIVSMALLAYAVASAYHSNVKLRRDGKMVLYPFPRVGRASGNTWQLPLNDLYPEYEPAQVKRQLYAFPRVGRDPVMSRLGRSDLSRVESHEFQPMAVRRTESPGMWFGPRLGRAFKNDDDEITIQNESNDHSEPEQTELIHEDRRKRQTLN
What is the function of this protein?
Myoactive.
What are the official names of this protein?
CAPA peptides.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBFA_SHEHH
Sequence: MAKEFSRTRRIAQQLQQELAQVLQRDMKDPRIGFVTVNDVDVSRDLSYAKVYVTFFEEDEKLVEQKVAALDAAAGYIRSLVAGRMKLRVMPELRFIYDSSLVEGMRMSNLVSRVISNDEAKQKQHGVETDAEQGETKDEGDK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIUX_APIME
Sequence: GLDLGLSRGFSGSQAAKHLMGLAAANYAGGP
What is the function of this protein?
Regulation of fluid secretion.  Stimulates primary urine secretion by Malpighian tubules and causes a dose-dependent stimulation of cAMP levels in the tubules.  Has a nonselective effect on Na(+)/K(+) ion transport.  In vitro, primarily elevates intracellular Ca(2+) (By similarity).
What are the official names of this protein?
Diuretic hormone class 2, Diuretic peptide, DP, GLDLGLSRGFSGSQAAKHLMGLAAANYAGGP-amide.
What is the protein family that this protein belongs to?
Belongs to the diuretic hormone class 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUS4_SCHPO
Sequence: MTVTNTYNPTLFFTRVVFQRITKFTAKANEENEILFYALFVADLCLDMKGGLIAINKPSGRTSAQCLNELKKIISNSELAQYFRPAPPHPNDRNRRRRKSNRLPDIKIGHGGTLDPLASGVLVVGLGTGTKQLSSLLSCMKTYRATALFGCSTDTYDSAGKIIKIAVHIPTKEEILSGLDAFRGDISQLPPLYSALHIQGKRLYEYAREGIPLPESIKARSMHCEELILKDFIPKEEHTYTDPDEFASKEAIESEELLRPIEGGAERHDLLAKTEQDINPQDGDEKINAKSPTTNSVTDVAKDQTVTNPKKRKFEVTDLARGSRPAIGPIAVLDMTVSSGFYVRSLIHDLGRQVNSEAHMVDLVRLKQGSFALDDENCFDFSEFSAPGWEEKLAAAFKIDLKGDETS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.  Also catalyzes pseudouridylation of mRNAs with the consensus sequence 5'-GGUUCRA-3'.
What are the official names of this protein?
tRNA pseudouridine synthase 4, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase 4, tRNA-uridine isomerase 4.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: FPG_DESVH
Sequence: MPELPEVETIACGLRPALSGRRIVGVTVHNPGTLEGPLCTPAAFTEAVQGQRIADVGRRGKLLLVAFASLPPVGHAGQPRPEGLSSSTVRDFLVTHGFHAAGCATSVHACAPLLADGQQTRGRLAGHGDGMDGTSRTGSTLPGTGGTENSDAVAVADDDTVLGLAFHLKMTGRLFIHPPATPAGIHTRVVFDLEGGTRLFFDDARKFGYVRCITRRSLALWPFWRDLGPEPLETEARGFAARLARRRGRIKALLLDQKVVAGVGNIYADESLFRAGIRPDTQAHTLTPERLFALHGHLQDVLRESIAECGSSIRDYRDAHGDAGAFQNSFRVYGRGGQPCRHCGTTLATAQVAGRTTVFCPQCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: HYM1_YEAST
Sequence: MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLTQDNKRKVQEECTKYLIGTKHFIVGDTDPHPTPEAIDELYTAMHRADVFYELLLHFVDLEFEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLTVGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVSKEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPENLKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLDSQDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTHSTSPDSR
What are the official names of this protein?
Protein HYM1.
What is the protein family that this protein belongs to?
Belongs to the Mo25 family.
Protein: LCFA_ECO57
Sequence: MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVNMGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVVNVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAKGTLVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTTGVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELGGQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVSPGQPGELCVRGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRIVDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSLTEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA
What is the function of this protein?
Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase, Long-chain acyl-CoA synthetase, Acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Partially membrane-associated.