PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_ACHLI
Sequence: MDYIIELIKYIILGIIQGVTEIFPVSSSGHLVLFSNLFLGGEDINATLTLFLMITNMGSFLALLIYYFKDVKELVVDSFNFVFNKEKRKEIIVQENISYAVKLIIAIVPIGIAGLLIKDYLPTNLLSIGISLIITSLLLFLVFLLRNKKFSNDITFKNAGVIGLIQMFAVFPGISRSGITLVGGLSQKIEIKKVMRFSFLCYLLISIPVSGLGLYDAIKNPGTMSDIPGFSLAFIFSFIFSLLTIKIMHKYVTVKNLIWFSLYALTVGLVSITLYII
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPA_AGRVS
Sequence: MTQRMDKRFADLKEEGRPALVTYFMGGDPDFETSLAIMKALPQAGADVIELGMPFSDPMADGPAIQMAGQRALKAGQTLVKTLDMAREFRKGDQATPIVMMGYYNPIYVYGVEKFLDDALDAGIDGLIVVDLPPEMDDELCLPARKRDINFIRLATPTTDEKRLPMVLQNTSGFVYYVSMNGITGSALPDPSKVAGAVGRIKAHTDLPICVGFGVKTAEHARLIGASADGVVVGTAIVNQVALSLTKDDKATADTVQSVVTLVRGLASGVQTARLAAAQ
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ALG1_ASHGO
Sequence: MDTSSVTMHTERACCHQAQRAVAAMLDKAPSWLIWTAVLYVGLPFMLYWAVPYLFYHNKTKSRRIAIYVLGDLGHSPRICYHARSFSAAGWEVELCGYLEEQPPKDLLDDPRVTIRALPGASNAGKSLGQTARKVVLQTCHIVRQLWELRGCDYILIQNPPSIPLLPIVAIFKVLTRTRLILDWHNFAYTVLQLRVGRFLHPLVLVSYAVEFLFSRMADYHITVTAAMKDYLVQSFLLPARRIAVMYDRPGEQFRPLPAGERGAALAEPFIRGYIPAGFDVQRGDTILVTSTSFTLDEDINVLFGALKIYESAAAKFDTTLPRILLFVTGKGPLKGKYMEEVRNYKWERCTIHFLWLSAEDYPRLLQLCDFGVSLHTSTSGLDLPMKVLDMFGSGLPAFVMDYPAIGELVQDRVNGLRFTTRRELEQCLIFAIKDEHTRKVLKENALLESKNRWHQSWASAMSELQVVRQS
What is the function of this protein?
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation.  Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity).
What are the official names of this protein?
Chitobiosyldiphosphodolichol beta-mannosyltransferase, Asparagine-linked glycosylation protein 1, Beta-1,4-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NSRP1_MOUSE
Sequence: MAIPGRQYGLILPKKTQPLHRVLQKPSVFGSDSDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDSTVYEYDSVYDEMQKKKEENNPKLLPGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMENGEFDDKEAFVTSAYKKKLEERAEEEEREKRAAALEAHLDVTKQKDLSGFYRHLLNQAVGEEAAPKSSFREARTVIKEEKLRGYPDETNSESRPPQQSCVLQRGAQEAEENPDADREFDDESSEDGEKRDHKVKSRGEDTGASMKHPKHHKNRAHSRSSSEERGLGTKHHSRGSQSRGHEHQDRQSRDQESCHKDRSHREEKSSHRHREASHKDHYWKKHEQEDKLKGREQEERQDREGKREKYSSREQERDRQRNDHDRYSEKEKKRKEKEEHTKARRERCEDSGKHREREKPEGHGQSSERHRDRRESSPRSRPKDDLDQERSSKARNTEKDKGEQGKPSHSETSLATKHRLAEERPEKGSEQERPPEAVSKFAKRSNEETVMSARDRYLARQMARINAKTYIEKEDD
What is the function of this protein?
RNA-binding protein that mediates pre-mRNA alternative splicing regulation.
What are the official names of this protein?
Nuclear speckle splicing regulatory protein 1, Coiled-coil domain-containing protein 55, Nuclear speckle-related protein 70, NSrp70.
What is the protein family that this protein belongs to?
Belongs to the NSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Colocalizes with splicing factors SRSF1 and SRSF2 in speckles.
Protein: ORN_XANCP
Sequence: MADNVAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHSLETLEAMDEWNRNQHRRSGLWQRVLDSQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLHRQMSRLERYFHYRNLDVSTIKELARRWAPAVASGFAKSSAHTALSDVRDSIDELRHYRQFMGTLGGDNGGGVQN
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS7_CVCAK
Sequence: MLVFLHAVFITVLILLLIGRLQLLERLLLNHSLNLKTVNNVLGVTDTGLKVNCLQLLKPDCLDFNILHRSLAETRLLKVVLRVIFLVLLGFCCYRLLVTLI
What is the function of this protein?
May function in the formation of membrane-bound replication complexes or in the assembly of the virus.
What are the official names of this protein?
Non-structural protein 7a, ns7a, 11 kDa protein, Accessory protein 7a, X3 protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns7/ns7a protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: FBL32_ARATH
Sequence: MFLCVIIPCLCSYLCSLFSWLLGQIPSFLFDKINESWLTSTKRNVEIVKNLMDKISQLPDELLVKVLSFLSTKDAVSTSILSMRWKSLWMWLPKLEYNFRHYSVSEGQGLARFITSSLRVHKAPAIESLSLKFRYGAIGSIKPKDIYLWVSLAVHVSNVRELSLKLFNFAELPTKLPKSLCKCKSIVILKLKDEILVDVPRKVCLPSLKTLFLGRVTYSDANSLHRLLSNCPVLEDLVMERDKIDNLGKLSVIVKSLQRLTLKMSRPCHLDGLKMNSPSLKYLKVIDERLESDSDDESDSDSPRYFYDFEDMPKLEEADFVLTFQNIKKFFGSITSVKRLSLCLGVYTEEVICFHHSIHLIVEQ
What are the official names of this protein?
F-box/LRR-repeat protein At1g55660.
Protein: T1SB_ECOLX
Sequence: MSFNSTSKELIEQNINGLLSIHDSWLRISMDSVANITNGFAFKSSEFNNRKDGVPLIRIRDVLKGNTSTYYSGQIPEGYWVYPEDLIVGMDGDFNATIWCSEPALLNQRVCKIEVQEDKYNKRFFYHALPGYLSAINANTSSVTVKHLSSRTLQDTLLPLPPLAEQKIIAEKLDTLLAQVDSTKARLEQIPQILKRFRQAVLAAAVTGRLTKEDKDFITKKVELDNYKILIPEDWSETILNNIINTQRPLCYGVVQPGDDIKDGIELIRVCDINDGEVDLNHLRKISKEIDLQYKRSKVRKNDILVTIVGAIGRIGIVREDINVNIARAVARISPEYKIIVPMFLHIWLSSPVMQTWLVQSSKEVARKTLNLKDLKNAFVPLPSIEEQHEIVRRVEQLFAYADSIEKQVNNALARVNNLTQSILAKAFRGELTAQWRAENPDLISGENSAAALLEKIKAERAASGGKKASRKKF
What is the function of this protein?
The specificity (S) subunit of a type I restriction enzyme; this subunit dictates DNA sequence specificity.  The M and S subunits together form a methyltransferase (MTase) that methylates A-3 on the top strand and A-4 on the bottom strand of the sequence 5'-TGAN(8)TGCT-3'.  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated (PubMed:4568607, PubMed:12654995).  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage (By similarity).
What are the official names of this protein?
Type I restriction enzyme EcoBI specificity subunit, S protein, Type I specificity subunit S.EcoBI, S.EcoBI, Type-1 restriction enzyme EcoBI specificity subunit.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: LPXA_ACTSZ
Sequence: MIHSTAKIHPSAIVEEGAKIGENAIIGPFCVVEKDAEIGKGTILYSHVVVRGITKIGEDNRIYQGASIGEINQDLKYQGEATRTVIGNRNRIRENVTIHRGTAQGGWVTNIGDDNLFMVNAHVAHDCQIKNRCILANNATLAGHVELDDFVIVGGMSAIHQFVIVGAHVMLGGGSMVSQDVPPYVMAQGNHARPFGVNIEGLKRRGFDKPTLHAIRNVYKLIYRSGRTLEEVMPEIETYAQTESAVSFFLDFFARSTRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1322_MYCTU
Sequence: MARRRKPLHRQRPEPPSWALRRVEAGPDGHEYEVRPVAAARAVKTYRCPGCDHEIRSGTAHVVVWPTDLPQAGVDDRRHWHTPCWANRATRGPTRKWT
What are the official names of this protein?
Uncharacterized protein Rv1322.
Protein: DIR1_ARATH
Sequence: MAKRFLLLLPLLSSILLLAVSVTAYSTTTPYQGYKPEKFTHLHFYFHDVISGDKPTAVKVAEARPTTTLNVKFGVIMIADDPLTEGPDPSSKEVGRAQGMYASTAMKDIVFTMVFNYVFTAGEFNGSTIAVYGRNDIFSKVRELPIIGGTGAFRFARGYALPKTYKIVGLDAVVEYNVFIWH
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 1, AtDIR1.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: DUT_ECOSE
Sequence: MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: YD39_SCHPO
Sequence: MESSLDRLNFDEFVAKLLIHESKKKNKSFVDHGYIEKEKTKLRPNKVFLNNMVRNVQSHNRGINNRRRDQKRKQLISIKQDNDLNVSSERLSRRIDVPRPTSKKKRLYKETPDLDEPGSREKRVSQKGQLKIEKV
What are the official names of this protein?
Uncharacterized protein C13G7.09c.
Protein: CH60_PSESM
Sequence: MAAKEVKFGDAGRKKMLAGVNVLADAVKATLGPKGRNVIIEKSFGAPLITKDGVSVAKEIELKDRFENMGAQLVKDVASRANDDAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKATIAIVAELKKLSKPCTDTKAIAQVGTISANSDHSIGDIIAEAMEKVTKDGVITVEEGSGLENELSVVEGMQFDRGYLSPYFINKPDTMVAELDSPLLLLVDKKISNIREMLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAVLTGGTVISEEIGLSLETTTLEHLGNAKRVILNKENTTIIDGAGVKTDIDSRISQIRQQIGDTSSDYDKEKLQERLAKLSGGVAVIKVGAGSEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRSLQAIEGLKGDNADQDVGIALLRRAVEAPLRQIVANSGDEPSVVVDKVKQGSGNFGYNAASGEYGDMIEMGILDPAKVTRSALQAASSIASLMITTEAMIADVADEKAAGGGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_SHEWM
Sequence: MSQEVLTLAQDLISRPSVTPLDEGCQTLMAERLAAQGFEIESMVFEDTTNMWARRGKEGPLFCFAGHTDVVPVGDLNRWHTPPFDPVVIDGYLHGRGAADMKGSLAAMVVATERFVEKHPDHNGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWSLVGEPSSTHKLGDIVKNGRRGSLTGNLTINGIQGHVAYPHLADNPIHKAAPALDELARMKWDNGNEFFPPTSFQIANINGGTGASNVIPGALEVMFNFRYSTEVTAEILIQRVLNILDAHGLDYDISWIFNGLPFLTGDGPLLDATREAIKQVTGSDTDPQTSGGTSDGRFIAPTGAHVIELGPVNATIHKVNECVKVSDLELLTQCYEVILEKLLC
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: LMBD1_MACFA
Sequence: MATPGAASAELVIGWCIFGLLLLAILAFCWIYVRKYQSRRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKDWANANVSRQIEDTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDDDDTSKCTQIKTALKYTLGFVVICALLLLVGAFVPLNVPNNKNSTEWEKVKFLFEELGSSHGLAALSFSISSLTLIGMLAAITYTAYGMSALPLNLIKGTRSAAYERLENTEDIEEVEQHIQTIKSKSKDGRPLPARDKRALKQFEERLRTLKKRERHLEFIENSWWTKFCGALRPLKIIWGIFFILVALLFVISLFLSNLDKALHSAGIDSGFIIFGANLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIETNITSDNHKGNSTLSVPKRCDADAPEDQCTVTRTYLFLHKFWFFSAAYYFGNWAFLGVFLIGLIVSCCKGKKSVIEGVDEDSDISDDEPSVYSV
What is the function of this protein?
Lysosomal membrane chaperone required to export cobalamin (vitamin B12) from lysosome to the cytosol, allowing its conversion to cofactors.  Targets ABCD4 transporter from the endoplasmic reticulum to the lysosomal membrane.  Then forms a complex with lysosomal transporter ABCD4 and cytoplasmic MMACHC to transport cobalamin across the lysosomal membrane (By similarity).  Acts as an adapter protein which plays an important role in mediating and regulating the internalization of the insulin receptor (INSR) (By similarity).  Involved in clathrin-mediated endocytosis of INSR via its interaction with adapter protein complex 2 (By similarity).  Essential for the initiation of gastrulation and early formation of mesoderm structures during embryogenesis (By similarity).
What are the official names of this protein?
Lysosomal cobalamin transport escort protein LMBD1, LMBD1, LMBR1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle.
Protein: ASSY_SYNJB
Sequence: MGRAKKVVLAYSGGVDTSVCIPYLKHEWGVESVVALAVDLGQGAELEAIQAKALRAGAEQSLVREAVQALITDYAFPAIQANALYEQRYPLSTALARPLIAKLLVEVAEEVGADAVAHGCTGKGNDQVRFDLAIAALNPQLKVLAPAREWGMTREETIAYGERYGIPMPVQKSSPYSIDLNILGRSAEAGILEDADREPPEEVYALTRPISQTPDEPAYVEIEFEQGIPVGLDGQRLGPKALFEQLNSLAGLHGVGRIDMIENRLVGIKSREIYECPALMVLIQAHRELESLTLTRDVIHYKYGIETTYSQLIYNGLWYSPLREALDAFIRATQKSVTGVVRMRLHKGQAVCVGRRSPYSLYNPELATYGEGDQFDHRAAEGFIYIWGLPTRVWAQVHRG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_ACTP2
Sequence: MNPRRKSRLKVVVSIIFGVAVAAGLMLYALSQNIDLFYTPSEIVNGKNDDPDQKPEVGQRIRVGGMVVEGSVKRDDKTLKVEFEANDIGPSITVEYEGILPDLFREGQGIVAQGVLIEPTRLKATEVLAKHDENYMPPELGDKLKEQHGAAGISEADLKGTSARDKAEIERTLKTLQGEAN
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: ACCD_YERPA
Sequence: MSWIERILNKSNITQTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARARLHMLLDAGSEVELGSELEPKDILKFRDSKKYKDRISAAQKDTGEKDALVAMKGTLQGMPIVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLVCFSSSGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPVMRQTLASILSKLTHQPQPSVVESKADTVAQPENQADV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_STAEQ
Sequence: MNHLTTETRNIQTMHLDEMNLSDALKTMNQEDQLVPKAIEPVIPNLTKVIESAIQRFNNGGRIIYIGAGTSGRLGVLDAAECVPTFNVSPNDIIGIIAGGQKAMTVAIEGAEDDAEQGAQDLKNIHLQSKDIVVGISASGRTPYVKGALVYANKMNAETVALSCNVHSDISKNSNHVLEINVGPEVLTGSTRLKSGTAQKLVLNMISTMTMIGVGKVYDNLMVDLRPTNQKLIHRSIRIIQDVCDLNHQEAIELYEKSDHNIKIAIVMHLCSTTQQDARLRLKQNNGVIKQAINT
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: IBB1_AMBAC
Sequence: SSKWEACCDRCACTKSIPPQCHCADIRLNSCHSACESCACTRSIPAKCRCFDITDFCYKPCSG
What is the function of this protein?
Inhibits trypsin, chymotrypsin, plasmin and factor XIIa.  Does not inhibit factor Xa, thrombin and plasma kallikrein.
What are the official names of this protein?
Bowman-birk type proteinase inhibitor, TaTI.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: NU6C_NICTO
Sequence: MDLSEPIHDFLLVFLGSGLILGGLGVVLLPNPIYSAFSLGLVLVCTSLFYILSNSYFVAAAQLLIYVGAINVLIIFAVMFMNGSEYYKDFHLWTVGDGITSMVCISLFISLITTISDTSWYGIIWTTRSNQIIEQDFISNSQQIGIHLSTDFFLPFELISIILLVALIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RF1_VIBA3
Sequence: MKASILIKLETLVERYEEVQHLLGDPDVLGNQDKFRALSKEYSQLEEVTGCFKSYQQAQEDLEAAEEMANEDDAEMREMAQEEIKDAKANIERLTDELQILLIPKDPNDERNCFLEIRAGAGGDEAGIFAGNLFRMYSKFAEKKGWRVEVMSSNVSEQGGFKEMIAKISGDAVYGTMKFESGGHRVQRVPETESQGRVHTSACTVAVMPEIPEADLPEIKAGDLKIDTFRASGAGGQHVNTTDSAIRITHLPTGTVVECQDERSQHKNKAKAMAVLAARIVQAEEERRAAAISDTRRNLLGSGDRSDRIRTYNYPQGRVSDHRINLTIYRLNEVLEGDMQSLLDPVLQEHQADQLAALAEHN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM258_CHICK
Sequence: MELEAMSRYTSPVNPAVFPHLTVVLLAIGMFFTAWFFVYEVTSTKYTRDIYKELLISLVASLFMGFGVLFLLLWVGIYV
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Transmembrane protein 258, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258, Oligosaccharyl transferase subunit TMEM258, Protein NEF1.
What is the protein family that this protein belongs to?
Belongs to the OST5 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Endoplasmic reticulum. Cytoplasm.
Protein: TBB1_GEOCN
Sequence: MREIIHVSAGQCGNQIGAAFWETISGEHGINPSAIYEGTDPLQLERLSVYYNEAGNGKYVPRAVLVDLEPGVMDAVRSGTYGNLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDIVRREAENSDSLQGFQISHSLGGGTGSGMGTLLISKIREEYPDRMMATFSVVPSPKVSDTIVEPYNATLSVHQLIENADETFCIDNEALYDICQHTLKLKQPTHADLNQLVSGVMSGITTCLRFPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLSAPGQQSFRSLTVPELTQQLFDSKNMMAASDPKRGRYLTVAAFFRGKVSIKEVEDQMRSVQERNSAYFVEWIPNNVQTAICSVPPKDVKMSATFIANSTSIQELFKRVGDQFSAMFRRKAFLHWYTNEGMDITEFAEAESNMNDLVSEYQQYQNATVDDEDMEYEDELPLEDEM
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GET1_ASHGO
Sequence: MDYWILLVLAFLVADKSWHLTGLLATKLTSPERLQQLIRERQELHQQQQSLSAQDHYAKWTKNNRRLDVLDRDIARVRKNYLESVEATKARLAKLKLLVVTVPFTALKFYKGKLPVYALPKGMFPRFIEGTLEHGWLYMALAPLNMKQFSEGASVAVSLGIWLFALLRVLGAIEFVLETLREQNPQVATETAKVHARTAQAASAN
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: KHSE_STAAM
Sequence: MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPILCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGFYNDVSKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVRSLNSQVVSCHSELVDINISGVKERIVYQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.