PharMolix/UniProtQA huggingface dataset:
Protein: BOP1_ARATH
Sequence: MTKRSKGANEDKLIETKSKNVSGKSQKQKKPVEAESLKEEDLLQASGTDSDYDGDSLPGSLNSDDFDSDFSDSEDDGTHEGTEDGDVEFSDDDDVLEHDGSIDNEDDDGSEHVGSDNNEEHGSDEDSERGEAVEESDSSEDEVPSRNTVGNVPLKWYEDEKHIGYDLTGKKITKKEKQDKLDSFLATIDDSKTWRKIYDEYNDEDVELTKEESKIVQRILKGEAPHADFDPYAPYVEWFKHDDAIHPLSSAPEPKRRFIPSKWEAKKVVKIVRAIRKGWIKFDKPEEEPNVYLLWGDDSTSDQKSKHLTYIPPPKLKLPGHDESYNPSLEYIPTEEEKASYELMFEEDRPKFIPTRFTSLRSIPAYENALKESFERCLDLYLCPRVRKKRINIDPESLKPKLPSRKDLRPYPNSCYLEYKGHTGAVTSISTDSSGEWIASGSTDGSVRMWEVETGRCLKVWQFDEAIMCVAWNPLSRLPVLAVAMGRDLFFLNTELGTDEEQEITKERLHSGNIPEPDASVAAIVTWLPDELYGGIKIRHFKSISSIDWHRKGDYLSTVMASGETRGVVLHQLSKQKTQRLPFKIRGLPVCTLFHPSLSYFFVATRKDVRVYNLLKPGEATKKLETGLREISSMAIHPGGDNLIVGSKEGKMCWFDMDLSSKPYKTLKNHPKDITNVAVHRSYPLFASCSEDSTAYVFHGMVYNDLNQNPLIVPLEILRGHSSKGGVLDCKFHPRQPWLFTAGADSIIKLYCH
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (By similarity).  Plays an essential role in cell growth and survival through its regulation of ribosome biogenesis and mitotic progression (PubMed:26940494).
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog, Pescadillo-interacting protein 1, AtPEIP1, Protein BLOCK OF CELL PROLIFERATION 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: CAH2_CAEEL
Sequence: MIPWLLTACIYPCVIGPDFWGLLHGDWRMCTAGQMQSPVNIDPSQLLYDPHLMPINIEGNIVEAVFENTGQLPVVTVKDLPNRPTINITGGPTMPYRYKLHQISVHFGRADEGEKGSEHTVDRVRFPAEIQLLAYNSALYPNFSVAMTSPRGLLAVSVIVDIGKTTSVELRRLTVASQSINYKGQTTNLTDFQPSALLPKTSHYVTYEGSLTFPGCHETVTWVILNNPIYITNDDLQIWNEMQKTETKQPEPSYMTPAYRPLKSLNGRLVRTNINVGSKQSTVSSSCPSNVYVEMGYQANPGRNKRNDSVSRRYVPTSEVFEIDSIRPDDVSKAGSF
What are the official names of this protein?
Putative carbonic anhydrase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Secreted.
Protein: STAD4_ORYSJ
Sequence: MASSGLAVAATASSAWLCCPNHHIHTSSSRSRKHLLLHGLYGSAPARTRGRRPPVWTAAAATAAAPADTAASARREQVEIARSLNAWVEENMLPLLTPVDSAWQPHDFLPCSAAGGGEALAAFTEGVAELRAGAAGVPDEVLVCLVGNMVTEEALPTYQSMGNRAEGLADGTGVSPLPWARWLRGWTAEENRHGDLLNRYLYLSGRVDMRQVEATVHRLLRNGMEMLAPASPYHGLIYGAFQERATFISHGHTARLAGQHGDRALAKICGVIAADERRHEAGYTMASGRLFELDPDGMARALADVMRGKVTMPGQLMSDGRDGDGEHSLFARFSAVAERAGVYTARDYGDLVEHFVRRWRVAELAAGLSGEGRRAQEYLCGLAPKIRRMEELAHRRAARIEPAMARFSWIFDRPVMLG
What is the function of this protein?
Introduces a cis double bond in the acyl chain of an acyl-[acyl-carrier protein].
What are the official names of this protein?
Acyl-[acyl-carrier-protein] desaturase 4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SARM1_MOUSE
Sequence: MVLTLLFSAYKLCRFFTMSGPRPGADRLTVPGPDRSGGASPWWAAGGRGSREVSPGVGTEVQGALERSLPELQQALSELKQASAARAVGAGLAEVFQLVEEAWLLPAVGREVAQGLCDAIRLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLAKEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALANCALHGGQTVQRCMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVEHSGTLALVEPLVASLDPGRFARCLVDASDTSQGRGPDDLQSLVLLLDSSRLEAQCIGAFYLCAEAAIKSLQGKTKVFSDIGAIQSLKRLVSYSTNGTTSALAKRALRLLGEEVPRRILPCVASWKEAEVQTWLQQIGFSQYCENFREQQVDGDLLLRLTDEELQTDLGMKSSITRKRFFRELTELKTFASYATCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIRLGVHRTRILSAAREMLHSPLPCTGGKLSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVIAARNFVLVLSAGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPIIDGFEWPEPQALPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQGRPSQDSSAGSDTSLEGATPMGLP
What is the function of this protein?
NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (PubMed:25818290, PubMed:26686637, PubMed:27735788, PubMed:32312889).  Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (PubMed:21555464, PubMed:22678360, PubMed:25818290, PubMed:26686637, PubMed:26423149).  Wallerian degeneration is triggered by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADPR (cADPR) and nicotinamide; NAD(+) cleavage promoting cytoskeletal degradation and axon destruction (PubMed:28334607).  Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (By similarity).  Can activate neuronal cell death in response to stress (PubMed:19587044).  Regulates dendritic arborization through the MAPK4-JNK pathway (PubMed:17724133, PubMed:21555464).  Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38 (PubMed:21555464).
What are the official names of this protein?
NAD(+) hydrolase SARM1, NADase SARM1, NADP(+) hydrolase SARM1, Sterile alpha and TIR motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SARM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, axon. Cell projection, dendrite. Synapse. Mitochondrion. Note=Associated with microtubules.
Protein: TAR2_ORYSJ
Sequence: MAALRVGTRAVEGRFQASNGGGGGGGGMAPSSRLVAAHREAKPRSSHSAAPWKLPRRRAGAMPLWRVAVFASVALNVATLALLLHHYATSPPPHHHHHDAGLATRSSDAAVHRRARTASSMAPSTGKPAVTTDSVINLDHGDPTMFEEFWRETGDAAEVVIPGWQTMSYFSDVTNVCWFLEPELDRQVRRLHRVVGNAAVDGYHVLVGTGSTQLFMAALYALAPDAAAAAAGEPISVVSTAPYYSSYPAVTDFLRSGLFRWAGDADAFKGDSYIELVCSPNNPDGAIREAVLDPKTGNGRTVHDLAYYWPQYTPITKRASHDIMLFTVSKSTGHAGTRIGWALVKDRAIARKMTKFVELNTIGVSKDSQMRAAKVLAAVSDGYERRPEQTKETMTTPLRLFDFGRRKMVERWSMLRAAAAASGIFSLPEETSGFCNFTKETAATNPAFAWLRCDREDVEDCAGFLRGHKILTRSGAQFGADARYVRVSMLDRDDAFDIFINRLSSLK
What is the function of this protein?
Probable tryptophan aminotransferase involved in auxin (IAA) biosynthesis (PubMed:24654985, PubMed:29740464).  Required for auxin production to initiate multiple change in growth in response to environmental and developmental cues (PubMed:24654985, PubMed:29740464).  Functions upstream of YUCCA1 in auxin biosynthesis (PubMed:29740464).  Required for polar auxin transport (PubMed:24654985).
What are the official names of this protein?
Tryptophan aminotransferase-related protein 2, OsTAR2, Protein FISH BONE.
What is the protein family that this protein belongs to?
Belongs to the alliinase family.
Protein: RLMD_ENT38
Sequence: MAQFYSAKRRVTTRQIITVEATDLDPFGQGVARHNGKALFIPGLLPNERAEVTLTEDKSKYSRGQVKRRLNDSPERVAPRCPHFGVCGGCQQQHASVALQQSSKSTALARLMKHEVNEIISGEPWGYRRRARLSLSYEPKTQKLAMGFRKAASSDIVDVKQCPVLVPHLEALLPHLRNCLSDLQGARALGHVELVLADNGPLMVLRHTAPLSAPDREKLERFSHSHELTLFLAPQSEILERVSGDDPWYLSDGLRLTFSPRDFIQVNDGVNQQMVAKAIEWLDVQPDDRVLDLFCGMGNFTLPLAQRAASVVGVEGVNALVEKGQQNAHHNALDNVTFFHENLEEDVTQQPWAQHGFDKVLLDPARAGAPGVMQHIIKLAPKRVVYVSCNPATLARDSEALLSAGYQIQRLAMLDMFPHTGHLESMVLFQL
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: OBG_RHOCS
Sequence: MKFLDQCKIYLKSGDGGPGAVAFRREKFIEFGGPDGGNGGRGGDVIIEAVDGLNTLIDYRYQQHFKAKRGGHGMGRSRSGAKGEDAVLRVPVGTQVLDDDQETVLADMTEVGQRIVLLKGGDGGFGNEHYKSSTNRAPRQFTPGWPGEERWVWLRLKLIADAGLVGLPNAGKSTFLAAVSRARPKIADYPFTTLTPNLGVVQAGEEEFVLADIPGLIEGAHEGRGIGTRFLGHVERTRVLLHLVDGTQEDVQLAYRTIRRELRLYGGGLAEKPEIVALNKIDALTPEELEFKRTKLRRSAKKPVMLLSGATGQGVQEMLFELLRHIREARGAEAEAAEEIERRIRYAPIEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_SALG2
Sequence: MNTLPEQHANTALPTLPDQPQNPGVWPRAELTVAGIKARIDIFQHWLGEAFDSGICAEQLIEARTEFIDQLLQRLWIEAGFGQIADLALVAVGGYGRGELHPLSDIDLLILSRKKLPDEQAQKVGELLTLLWDVKLDVGHSVRTLEECLLEGLSDLTVATNLIETRLLIGDVALFLALQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTPAERAELNECLHILWRIRFALHLVVSRYDNRLLFDLQLSVAQRLNYSGEGNDPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPVDDEFQLRGTLIDLRDDTLFIREPQAILRMFYMMVRNSAITGIYSTTLRHLRHARRHLSQPLCYIPEARTLFLSMLRHPGAVSRGLLPMHRHSVLWAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFAKEETRQRHPLCVDLWPRLPHPELILIAALFHDIAKGRGGDHSVLGAQDVLTFAELHGLNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTETRLRFLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEAALHKIWTRCRANYFVRHSPNQLAWHARHLLQHDLRQPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLAADRHEVIRTGLEQTITQRSWQPPQPRRQPAKLRHFTVETEVNFLPTHTDRKSFMELIALDQPGLLARVGQIFADLGISLHGARITTIGERVEDLFIIATADRRALNNVLQLEVQQRLTAALNPNDKG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: GRPE_LEGPA
Sequence: MSKQNKKDWKKFKDEHKEEHKVENEILEEEIDEKSQHQEPALGHPSYTALEEQLTLAEQKAHENWEKSVRALAELDNVRRRMEREVANAHKYGVEKLISALLPVVDSLEQALQLADKNSDPSMHEGLELTMKLFLDALQKFDVEQIDPLGQTFDPQQHEAMSMQPAPGAPPNSVITVFQKGYKLSDRVIRPARVIVSTK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPC29_YEAS1
Sequence: MDYSNFGNSASKKFQDDTLNRVRKEHEEALKKLREENFSSNTSELGNKKHYRAQERMSSPLHRLSPTGKSDDRKVKSPLDDKLRRQLREGNTRLPPPPFSSYGMPPTNRSNLDRIRRRTSSPVRTDKFASQNVIDDQRLEIKYLERIVYDQGTVIDNLTSRITRLESFILNSISDRGDKNFASLEHSRSFSGFPTNKTYGLQMGGLYENDMPYRRSSDNINKEGAREDRSSQIHIENESTEDILKILSSSFHN
What is the function of this protein?
Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication.  Links the central plaque component SPC42 to the inner plaque component SPC110 (By similarity).
What are the official names of this protein?
Spindle pole component 29.
What is the protein family that this protein belongs to?
Belongs to the SPC29 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: ZN542_HUMAN
Sequence: MLENYQNLVWLGLSISKSVISLLEKRKLPWIMAKEEIRGPLPGYFKVSEMTISQEPKAKTRTLFGKDVPGAEIKELSAKRAINEVLSQFDTVIKCTRNVCKECGNLYCHNMQLTLHKRNHTQKKCNQCLDCGKYFTRQSTLIQHQRIHTGERPYKCNECIKTFNQRAHLT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Putative zinc finger protein 542, Zinc finger protein 542 pseudogene.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EUTC_PSEFS
Sequence: MKEPPVQLDLPDNPWLELRRLTPARIALGRTGTSIPTNAQLDFQFAHAQARDAVHLPFDPAGLSSQLAERGRDSLLLHSAAADRHSYLQRPDLGRRLSDESAQALRDHASANPGGVDLAVVVADGLSALAVHKHTLPFLTRMEEQTHAEGWSLSPVILVEQGRVAVADEIGQLLGAKMVVILIGERPGLSSPDSLGLYFTYNPKVGLTDAYRNCISNVRLEGLSYGMAAHRLLYLMREACRRQLSGVNLKDEAQVQTLESDDPDLMKGNFLLSSPDD
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: GRPE_ECO8A
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMS1_PROAN
Sequence: MLSCRFQCALVLLSLAVVFSKVSAAPSDLRLRQLLQRSLAAAAGKQELTKYSLAELLSELAQSENDALDSSDLSRGADQDEVRLELDRSANSSPLAARERKAGCKNFFWKTFTSC
What is the function of this protein?
Somatostatin inhibits the release of somatotropin.
What are the official names of this protein?
Somatostatin-1, PSS1, Somatostatin I.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIL20_YEAST
Sequence: MKSKVSPSFHFFIFFFLFCLLRTLDYNTYNTNHNDTYMHIKLFFSYYFRFVHLFFFLYYAHLRTTKHYHTLLIQYYPFEMHWSKDLAQRPSSLRLRYFPAYLKRCCYHPMQN
What are the official names of this protein?
Putative uncharacterized protein YIL020C-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FATE1_BOVIN
Sequence: MAGGAVPNLKEKMQVPKDEDLLLGSFRDNQECSVAAEMKEHMSRLLGASQRRQRVDPKAVGSAVVWNTAANQSKKMGPQLRGVGVVGEQGDGGAQPQENPGGSQGMRSQFERRELNTLAEIGLEELNELEMEIMRRQLFMITERLRYLEDQSATWHQREVLLFTMLLSSCITNLWLWMRQ
What is the function of this protein?
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling.  Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis.  May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
What are the official names of this protein?
Fetal and adult testis-expressed transcript protein homolog.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane. Endoplasmic reticulum membrane; Single- pass membrane protein; Cytoplasmic side. Note=Localized to specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria. Also associated with the outer surface of mitochondria at sites that are not in close contact with the ER.
Protein: HEM1_THEAC
Sequence: MQILTLISWDFKRNNNFFNQAVLNPYEYWADILEKNGISRYVILLTCNRVEIYLRAGFPEDLEAMKPNVLHDEEAIKHLMEVSSGLDSMSLGENEILKQVKEAYELSVRNGKVDKVLSLIFQKAIFVGKKVRSETEISRGKVSVPSIVYDILSSRVVQKVLIIGNGMIAGEIAPYLSGKFEVTIAGRNIDHVKDLASKYNYSYTTINDLHELIMRNDAIISATSSKTPIIRREEMVEGKLYIDLGNPRNIEDKPGADIITIDDIYSVSNRNGSARMESVDEARRIIEIEMASLMNKIKDVMIDEIFADFYKFAVVVQKMEIEKFSRMHPEIPASDVEAFAHSMINKVMNIPVMTLKSVARSQSNQDFSRIFSKFYDNFSDLVSAALQSYEGRQDTQSLRDRTRRLLQRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: E306_ADE35
Sequence: MGNAGPLKLHTITKPGTIPYPPHGSQEFPSGTLSLSEVLTVPSALVTTLSFFLKCAIWPCS
What are the official names of this protein?
Early E3 6.4 kDa protein.
Protein: NACA_USTMA
Sequence: MSATVEEIADDVQDLNVQEFDSDDAGADVHASDKVASRAERKSRKALQGIGLKKVGGITRVTMRRPRGHLYVIAQPEVYKSSHSDVYIVFGEAKAEDMSQLAQAQAAQQMAQAEAQERLLAESLQNSSASGAEKKVEEEEEDDDSPIDEEGVDAKDIDLVMQQVSCSRRKAVKALKESNGDLINAIMNAS
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD2 may also be involved in transcription regulation (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: RF2_EXIS2
Sequence: MELAEIRNTAEWMEKKLDEYKASLDLETKISRIEELENEMTYPDFWNNQESAQKVIDESNGLKAMVDKYQHLADGHENIVLTYELIKEEPDVELQEELESELGDIKKKFDEFELQILLNGEYDANNAILELHPGAGGTESQDWASMLLRMYQRFCDKQGWKVETMDYQPGDEAGVKSVTLRIQGHNAYGYLKAEKGIHRLVRISPFDSSGRRHTSFVSCDVMPEFNDDIDIEIRTEDLRVDTYRASGAGGQHINTTDSAVRITHVPTGVVVSCQQERSQIKNREAAMKMLKAKLYQREIEEKQKKLDEIRGEKSDIAWGSQIRSYVFHPYSMVKDHRTNYEVGNTQGAMDGDIMGFIDAYLRLMNM
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_BRUA2
Sequence: MRVSVFAVGRMKSGPERELVERYFDRFAKAGPPLGLEFAGVSEIPESRGQTAQLRKAEEAQRIHEALDNAKSGGTSSGGAALILLDERGKTLGSEAFAAIVGRMRDDGKRQLIVAIGGPDGHDPALRSRADLVLALGELTWPHQIARILIAEQLYRAATILAGHPYHRS
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTA_ECOLI
Sequence: MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA, C-type cytochrome biogenesis protein CycY.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y089_METJA
Sequence: MSLMILSVDGVEFAYKSRQILNNIKFEVKRGEVVSILGVNGAGKSTLLKCINKILKPKRGTILIDNFDIKNLDNLELAKKVGYVPQRAEGNYMTVFDAVLLGRKPHIKWEVSDRDIEITHKVLKLLNLEDYALRYTNELSGGELQKVIIARALVQEPQILLLDEPTNNLDLKNQLEVMKIIMDISKSQNIASIVVMHDLNLALRYSDKFIMLKDGVIYAEGGREVINPENIKAVYGVDAYIENVRGIPVVVPIG
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein MJ0089.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: ERPA_ESCF3
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CRCB2_STAA8
Sequence: MISIILVMIGGGFGAIARSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPAFFVTGFLGGLTTFSTLAKELTLMMTPKFNINLFLNYSLLQFIIGFIACYIGYHI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBE2F_HUMAN
Sequence: MLTLASKLKRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYAR
What is the function of this protein?
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins.  The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
What are the official names of this protein?
NEDD8-conjugating enzyme UBE2F, NEDD8 carrier protein UBE2F, NEDD8 protein ligase UBE2F, NEDD8-conjugating enzyme 2, RING-type E3 NEDD8 transferase UBE2F, Ubiquitin-conjugating enzyme E2 F.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.