PharMolix/UniProtQA huggingface dataset:
Protein: TBCE_RAT
Sequence: MSDILPLDVIGRRVEVNGEYATVRFCGAVPPVAGLWLGVEWDNPERGKHDGSHEGTMYFKCRHPTGGSFVRPNIVNFGEDFLTALKKRYVLTDGPDDDEKSCSLKVGSKQVQTIGFEHITKKQSQLRSLQDISLWKCAVSCAGERGRIAEACPNIRVVDLSKNLLSTWDEVILIAEQLKDLEALDLSENKLQFPSDSPTLTRTFSTLKTLVLNKTGITWTEVLHCAPSWPVLQELYLKSNGISISERPVNALQNLRLLDLSSNPSIDESQLCLIAYLPRLEHLLLSDIGLSSIHFPDAEIGCKTSMFPALTYLIVNDNQISEWSFINELDKLQSLQALSCARNPLTKGDKAEEIIIAKIGQLKTLNRCQILPEERRGAELDYRKAFGKEWRKAGGHPDPDRNRPSAEFLSAHPRYQLLCCKYGAPEDEELKTQQPFMLKNQLLTLKIKCSNQPEQQILEKQLPDSMTIQKVKGLLSRLLKVPVSELLLSYESSKMPGREIELENDLQPLQFYSVENGDCLLVRW
What is the function of this protein?
Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation.  Required for correct organization of microtubule cytoskeleton and mitotic splindle, and maintenance of the neuronal microtubule network.
What are the official names of this protein?
Tubulin-specific chaperone E, Tubulin-folding cofactor E.
What is the protein family that this protein belongs to?
Belongs to the TBCE family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: G6PI_SYNS9
Sequence: MSFPDFSASDAQIQWQRFCDLLWYHDDLGLWLDVSRMHLNASELEALQPAMDRAFTAMHELEAGAIANPDEERQVGHYWLRNPQLAPSDDLRTHIAREVDDIEAFGRGVVHGEIKAPSGVPFTDVLWIGIGGSGLGPALMIRALKNNNQGLPFHFLDNVDPNGMSNVLGGLAGRFKTTLVVTVSKSGGTPEPHIGMEQARLKLEAAGGKWAGQAVAITMLNSRLDQQAQQEAWLKRFDMFDWVGGRTSITSAVGLLPGALIGCDIRDFLAGAAQMDEATRVADSRRNPAALMAASWYVAGEGKGRRDMVVLPYRDRLEVFSRYLQQLVMESLGKRLDRDGNVVHQGIAVYGNKGSTDQHAYVQQLRDGVDNFFATFIEELEDSEDIPVIKNERPGDFLDGFLQGTRSALTEGGRQNMTITMRCFDERRLGALVALFERAVGLYGELVNVNAYHQPGVEAGKKAAAAILDLQQRVEEVLQDGVPRTVSEIRQVLDDGSDESIFWIMRHLTGNKRQYNAQGDWSSPAGMRFSKD
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYW1_PYRAB
Sequence: MREMITIKPGKITVQANPNMPEEVANLFRKQHYEIVGRHSGVKLCHWLKKSLTEGRFCYKQKFYGIHSHRCLQMTPVLAWCTHNCIFCWRPMETFLGTELPQPWDDPEFIVEESIKAQRKLLIGYKGNPKVDKKKFEEAWEPKHAAISLSGEPMLYPYMGDLVEEFHKRGFTTFIVTNGTVPERLEEMIKEDKLPTQLYVSITAPDIETYNSVNIPMIPDGWERIMRFLELMRDLPTRTVVRLTLVKGENMHSPEKYAKLILKARPMFVEAKAYMFVGYSRNRLTINNMPSHQDIREFAEALVKHLPGYHIEDEYEPSRVVLIMRDDVDPQGTGVNGRFIKH
What is the function of this protein?
Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
What are the official names of this protein?
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, tRNA wyosine derivatives biosynthesis protein Taw1.
What is the protein family that this protein belongs to?
Belongs to the TYW1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CHESB
Sequence: MRHGKAGRKLNRTSSHRKAMFANMAASLIEHEQIVTTLPKAKELRPIVEKLVTLGKRGDLHARRQAIAAIRSETLVRRLFDTLAPRYASRNGGYTRIMKAGFRHGDNAAMAVIEFVDRDPSVKGAADRARVEAEAANEEAEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ISPDF_DESAP
Sequence: MADTLAIVVAAGRSSRMGEGPKKQYRLLAGRPVLGRTLEVFEHAPAVDGVVLVVAPGEEDWCREEIVTRFGFTKVVAVVPGGEVRRDSVWAGLQALPPCALVLVHDGVRPFVTARQIAAVAEAARECGAATLAVPPKDTVKLGGPPGAPVSTLPRENLWLVQTPQAFRFDVLIKAHHLARERGLAATDDTSLAEAAGYDVRMVPGAYTNIKITTPEDLAFAEALLGGGPVLVGFGYDVHRLVDDRKLILGGVEVPHDRGLLGHSDADVLVHAVMDALLGAAGAGDIGRWFPDDDPTYRGISSMDLLVRVAAFLRERGLETSNLDAVVVAEAPRLSPFISRMRDNLASVLGVSPAAVNVKATTTEGLGFTGSGAGIAAYAVAALRRIVLPGDRVL
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: RS17_SHESH
Sequence: MSDNIRTLQGRVLSNKMDKSITVAIERKVKHPLYGKYLKRTTKIHAHDEQNQCNAGDVVTIRECRPLSKTKSWTLVEVVSKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: GUNA_RUMFL
Sequence: MLKSRGIIKGINLGGWMSQCDYSRERLDNFVKENDIKQIADWGFDHVRLPIDYNIVQNNDGSVIEDGYNRIDKVVELCRKYGLKLVIDLHKTAGFSFDFGEPESGFFDNKEYQERFYILWEEIARRYGHDTDNIVFELLNEVTDEAFIGKWNEISDICIGRIRKIAPEVIILLGSYHNNAADTVQFLNAPHDDRVVYNFHCYEPLKFTHQGATWTPDIIPGERMKFEDSETSEAYFEELFSTAISTAEKYGTTLYCGEYGVIDVVSAEDSLKWFKVINKVFSKHGISRECGITRKWTSAFPTASTTATVRDTEVSVIKTRKAHNCCTLTEVFTRVY
What is the function of this protein?
Crystalline cellulose degradation.
What are the official names of this protein?
Cellodextrinase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted. Note=Seems to be exported by a mechanism other than a leader peptide.
Protein: Y3316_PSEAB
Sequence: MIVRTLLIAAALLGGTAQAAESTDLCGANLQKLDDILAVRGKTSVTGARVTEVKELQAKARQDQASGDTKGCITATTQALQILQNAGKK
What are the official names of this protein?
Uncharacterized protein PA14_33160.
What are the subcellular locations of this protein?
Secreted.
Protein: PIMT_DANRE
Sequence: MAWKSGGASHAELVNNLRKNGIIKSDRVYEVMLATDRSHFSRCNPYMDSPQSIGYQATISAPHMHAYALELLHDHLYEGAKALDVGSGSGILSVCFSRMVGPTGKVIGIDHIKELVEDSIANVKKDDPSLITSGRIKLIVGDGRMGFTEEAPYDAIHVGAAAPTVPQALLDQLKPGGRLILPVGPAGGNQMLEQYDKLEDGSTKMKPLMGVIYVPLTDKDKQWSRDEL
What is the function of this protein?
Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins.
What are the official names of this protein?
Protein-L-isoaspartate(D-aspartate) O-methyltransferase, PIMT, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: UREG2_BRUO2
Sequence: MKKIPRIGVGGPVGSGKTAIIEAVVPILIKLGYRILVITNDIVTTEDAKHVQRTLKGVLIEDRIVGVETGGCPHTAVREDPSMNLAAVEEMEAKFPDTDLVLLESGGDNLTLTFSPALIDFFIYVIDVAAGDKIPRKNGPGISQSDILVINKTDLAPYVGASLQVMDDDSRMMRGKKPFVFTNCKTNEGIDDLVHLIRENVLFDTEVSKESA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 2.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_STRPG
Sequence: METWQEVTVHVHRDAQEAVSYVLIETGSQGVAIADSADYIGQKDRFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKMSLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQGTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKDQGYLILSGIISEKLDMVLEAAFSAGFFLETHMIQGEWNALVFKKTDDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITD_HAEDU
Sequence: MQITKTAVAGTLESSDVQIRIAPSTTMDIEINSSVAKQFGEDILNSVTAVLAQFEVSSAQIIIEDKGALDCVLRARLKAALLRATDEALAWEKIL
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP7_MOUSE
Sequence: MASSLLEEEAHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKGGTKKPYADLSAPKTMGDAYPAPFSSTNGLLSPAGSPPAPASGYANDYPPFPHSFPGPTGAQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLSTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQLEGSGAAKPPRGAGTGGSGGYAGSGAGRSTCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSVGEEEANQPPRSSTSPAPPEKAHGGSPEQSNLLEI
What is the function of this protein?
Transcriptional activator essential for osteoblast differentiation (PubMed:11792318, PubMed:17510056, PubMed:30026585).  Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (PubMed:11792318, PubMed:17510056).
What are the official names of this protein?
Transcription factor Sp7, C22, Zinc finger protein osterix.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TEB1_SCHPO
Sequence: MRSMKPPGFSSDLMDEHSVDLLNGSILAAENPSKREVAQDVPGFERKPTKVRKPRVKWTEKETNDLLRGCQIHGVGNWKKILLDERFHFTNRSPNDLKDRFRTILPEDYKKFYPNAKTHMGRPQKIPHTVGLSKSTRKERKQFTPEEDERLLEGFFLHGPCWTRISKDANLGLQNRRSTDLRDRFRNAFPERYAAAGFKLKNNPGNRSKYYQNNMVNDATTPNDSSTTEAAAAAVAAVAAVAASNPNASPQQTTEQPASDELLDWPHHNLPSQFFTSQRNPNYSTDSFLLGQSLSDPFNHTLQSFHPYESLFSAGQPPSLPISPSTSQNSVQPFPFSIQQPPLHLEPPLSSNTLNSSTLPQPNSTDFNTFPPLPSTPRISSEDIPWDNRG
What is the function of this protein?
General transcription factor with prominent roles in controlling histone levels and stability.  Binds and regulates the activities of many promoters, including those controlling the expression of all four types of canonical histones.  Is also involved in the centromeric loading of cnp1 and maintenance of centromere identity.  Moreover, regulates the expression of cdc2, a protease capable of histone clipping.
What are the official names of this protein?
Telobox protein 1, Meiotically up-regulated gene 152 protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLYCO_RABVI
Sequence: MVPQVLLFVPLLVFSMCFGKFPIYTIPDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSGFSYMELKVGYISAIKVNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVKTTKESLVIISPSVADLDPYDKSLHSRVFPSGKCSGITISSTYCSTNHDYTIWMPENPRLGTSCDIFTNSRGKRASKGGKTCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSDETKWCPPDQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMATKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEIIPSKGCLRVGGRCHPHVNGVFFNGIILGPDGHVLIPEMQSSLLQQHMELLESSVIPLMHPLADPSTVFKDGDEAEDFVEVHLPDVHKQISGVDLGLPSWGKYVLVSAGVLVVLMLTIFIMTCCGRVHRPKSTQHGLGGTGRKVSVTSQSGKVISSWESYKSGGETRL
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane.  There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: CLC2L_RAT
Sequence: MEPAREPPARARPPPPAARPAPAAPRPRSPAEAEARGPEGLLRRSGSGYEGSTSWKAALEDTTTRLLLGAIAVLLFAILVVMSILASKGCIKCETPCPEDWLLYGRKCYYFSEEPRDWNTGRQYCHTHEAALAVIQSQKELEFMFKFTRREPWIGLRRVGDDFHWVNGDPFDPDTFTISGTGECVFVEPTRLVSTECLTTRPWVCSKMAYT
What are the official names of this protein?
C-type lectin domain family 2 member L.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SL9B_BOTJA
Sequence: DCPSDWSPYEGHCYRVFTEPQNWADAEKFC
What is the function of this protein?
Anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factors IX (F9) and factor X (F10) in the presence of calcium with a 1 to 1 stoichiometry.
What are the official names of this protein?
Snaclec coagulation factor IX/factor X-binding protein subunit B, IX/X-bp subunit B.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: BPT_RHORT
Sequence: MDQGPINRPHFFFTTAPMPCPYLEGHLERKMVTDLTGPEAERLHESLSRAGFRRSHTIAYAPVCPGCTACVPVRIRARAFVKNKSFRRIVRANAGVTAEYVPARATVEQFHLFSQYQQARHGESDMALMGFFDYRSMVEDSPISTSIAEFREAGGELVAACLIDHLSDGLSAVYSFFNTTLPQSRGLGTWMILWMVDETVRRDLDHVYLGYWIAESSKMAYKERFQPLEVFGRRGWIAFDERGRPG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_HELPG
Sequence: MKTPKMNVESFNLDHTKVKAPYVRIADRKKGVNGDLIIKYDVRFKQPNQDHMDMPSLHSLEHLVAEIIRNHANYVVDWSPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKATEVPASNEKQCGWAANHTLEGAKNLARAFLDKRAEWSEVGV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RUTA_SHIF8
Sequence: MMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSIPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDATRAKWEHYKAGADEEVLSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLSALTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: PAX9_CALGO
Sequence: MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQGHYDSYKQHQPAPQPALPYNHIYSYPNPITAAAAKVPTPPGVPAIPGSVAMPRTWPSSHSVTDILGIRSITDQVSDSSPYHSPKVEEWSSLGRNNFPAAAPHAVNGLEKGTLEQETKYSQAPNGLPAVGSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGHGWQHAGSTPLSPHNCDIPASLAFKGMQAVREGSHSVTASAL
What is the function of this protein?
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
What are the official names of this protein?
Paired box protein Pax-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: PQQD_PSEU2
Sequence: MKHDPQFRALTPKWHQGYRFQYEPAQKAHVVLYPEGMIKLNESAALIGGLIDGKRTIAAIIDELHQQFPNVPELGMDVDEFMEGAKKKNWIDLV
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.
Protein: MFR1L_HUMAN
Sequence: MSGMEATVTIPIWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLRDVPPVPTLADIAWIAADEEETYARVRSDTRPLRHTWKPSPLIVMQRNASVPNLRGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAASASLTPDFLSPGSSNVSSPLPCFGSSFHSTTSFVISDITEETEVEVPELPSVPLLCSASPECCKPEHKAACSSSEEDDCVSLSKASSFADMMGILKDFHRMKQSQDLNRSLLKEEDPAVLISEVLRRKFALKEEDISRKGN
What are the official names of this protein?
Mitochondrial fission regulator 1-like.
What is the protein family that this protein belongs to?
Belongs to the MTFR1 family.
Protein: CYSC_ECOHS
Sequence: MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: MED9_YEAST
Sequence: MNLQNNVLNQIHQILLPTNPTLDKPNAEATKEEFSSAENRDEKDYLTNQQPKNLSTPSTSSNGEFIPHIFYSLHQIRKDPNNLSNQLETLTGSIRHRLKLCKSLISENEDTKDLLSKSPSEWQDIIHQREQELQIKRDVLDDLYRKLQR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II.  The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 9, Chromosome segregation protein 2, Mediator complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MQO_ACIBT
Sequence: MKKFLKYLLVLIILILIAGIVFLFRPIASKQVQTAKDEPVVDAVLVGGGIMSATLGTYFTELEPNWQIRMFERLDQVAQESSNGFNNAGTGHSGFMEMNYTEEKNGKMEIAKAEKVASQFEVAKQFWSYQVKQGVLAEPKTFINPVPHIAFVWGDNVKFLEKRYAAMIQSPLFKGMKFTEDPAVIKQWAPLVMTDRDPTQKVAATRMEVGSDVNYGSITKQLVNHLNQNPNFKLQTSTEVTGISQNDDKTWTVSFKNLKTGKTDHVKTRFVFIGAGGAAVKLLQLTGLPEAKQYAGFPVGGEFLITDNPAITAQHTAKVYGRAELGAPPMSVPHIDTRYIDGKKYVLFGPFATYSNKFLKNGSQLDLLASTNKSNVLPMTTVGLENLDLVKYLVSQVMMSDEDRLNELRKYYPDAKAEDWRLSQGGQRVQIIKKEPGKPATLQFGTEIFASKDGAVTALLGASPGASTSPYIMLNLLEKAFPQQTEGKWNQKLHEIVVSYKQDLSKDPVLLDKVRQYTSSTLGLNYTSPFKAANDETAAAPVAKAN
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: Y4435_MYCA1
Sequence: MTRTDQDSWDLASSVGATATMVAAARALASTGERPIINDPFAAPLVRAVGLDFFRRLVDGEVAPADPQRGERDLQLETDSIAVRTRFFDDFFTGAARDGIRQSVILAAGLDARAYRLDWPAGAVVYEVDQPKVVEFKTNTMAALDARPAAQLRTVSIDLREDWPEALRANGFDVTQATSWSAEGLLMYLPPEAQDRLFDNITALSAPGSRLATEYHPDATGTTMAQRAQEFNDRWARVGCDIDLSGLFFDGERSNVVEYLTGRGWRVSARPRRDLFDDYGLAYPEDDETAQFPNIVAVSAELG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4435.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: FER4_RHOCA
Sequence: MDKATLTFTDVSITVNVPTGTRIIEMSEKVGSGITYGCREGECGTCMTHILEGSENLSEPTALEMRVLEENLGGKDDRLACQCRVLGGAVKVRPA
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.  This ferredoxin is required for nitrogen fixation (By similarity).
What are the official names of this protein?
Ferredoxin-4, Ferredoxin IV, FdIV, Ferredoxin, plant-type.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
Protein: RTJK_DROFU
Sequence: MTQPTIKIGLWMHRGLTRGSEELRLFLSVHNIDVMLVTESHMREGQRIFLPGYSTYHVFHPSGNSRGGASVIVRSSISHSPQPPISTNDRQIAYIQLQTAEGPVVLAAVYLPPRERWIRAEFESLFAVLGNKFIAGGDYNAKHAWWGNSRACARGKVLQEVVANGQYQILATGEPTFYSYNPLVSPSALDFFVVNGYDMRRLNVQTLHELSSDHTPLLADLHAMPINKPPRSCLLARGADIERFKAYLTQHIDLSVGIQGTDDIDNAIDSFMDILKRAAIRSAPSHQQNVESSRQLQLPPIVASLIRLKRKVRREYARTGDARIQQIHSRLANRLHKVLNRRKQSQIDNLLENLDTDGSTNFSLWRITKRYKTQATPNSAIRNPAGGWCRTSREKTEVFANHLEQRFKALAFAPESHSLMVAESLQTPFQMALPADPVTLEEVKELVSKLKPKKAPGEDLLDNRTIRLLPDQALLYLVLIFNSILRVGYFPKARPTASIIMILKPGKQPLDVDSYRPTSLLPSLGKMLERLILNRILTSEEVTRAIPKFQFGFRLQHGTPEQLHRVVNFALEALEKKEYAGSCFLDIQQAFDRVWHPGLLYKAKSLLSPQLFQLIKSFWEGRKFSVTADGCRSSVKFIEAGVPQGSVLGPTLYSIFTADMPNQNAVTGLAEGEVLIATYADDIAVLTKSTCIVEATDALQEYLDAFQEWAVKWNVSINAGKCANVTFTNAIRDCPGVTINGSLLSHTHEYKYLGVILDRSLTFRRHITSLQHSFRTRITKMNWLLAARNKLSLDNKVKIYKCIVAPGLFYAIQVYGIAARTHLNKIRVLQAKMLRKISGAPWYMRTRDIECDLKVPKIGDKIREVAKKYHERLDSHPNSLARRLGVAAQRSASPRSRVRRRLKRHHPQDLLDRALT
What are the official names of this protein?
RNA-directed DNA polymerase from mobile element jockey, Reverse transcriptase.
Protein: IL12B_SHEEP
Sequence: MHPQQLVVSWFSLVLLASPIVAIWELEKNVYVVELDWYPNAPGETVVLTCDTPEEDGITWTSDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSRSLLLLHKKEDGIWSTDILKDQKEPKAKSFLKCEAKDYSGHFTCSWLTAISTNLKFSVKSSRGSSDPRGVTCGAASLSAEKVSMDHREYNKYTVECQEGSACPAAEESLPIEVVMEAVHKLKYENYTSSFFIRDIIKPDPPKNLQLRPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKNKREKKLFTDQTSAKVTCHKDANIRVQARDRYYSSFWSEWASVSCS
What is the function of this protein?
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity.  IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues.  IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines.  IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity).
What are the official names of this protein?
Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40.
What is the protein family that this protein belongs to?
Belongs to the IL-12B family.
What are the subcellular locations of this protein?
Secreted.