PharMolix/UniProtQA huggingface dataset:
Protein: PIG8_CLAP2
Sequence: MASYAVLGATGNCGSALIQLLLQRPDASIHAFCRNKPKLIGLLPEIEKSERVTIYQGSIKDTDLLTACLRGRRAVFMVLSSNINEPGFRVGRDANKAVIEVLRTLHREDSGSTGPPPKIILLSSATLDDTLSRKTPYLLRQILHMSASHIYNDLAETEKLLRAEQEWLTTVFVKPGALSVDEQRGHALSFVESDNPVSYLDLAAAMIEAADDTTDKYDMKNIGVVNTNGAARFPTGTPLCIATGLLRHFVPSLHPYLP
What is the function of this protein?
Oxidoreductase; part of the ergochrome gene cluster responsible for the typical purple-black color of the ergot sclerotia (PubMed:28955461).  The ergochrome gene cluster produces several ergot pigments including the yellow ergochrome secalonic acid and its derivatives, as well as the red anthraquinones endocrocin and clavorubin (PubMed:28955461).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) CPUR_05437 (By similarity).  The atrochrysone carboxyl ACP thioesterase CPUR_05436 then breaks the thioester bond and releases the atrochrysone carboxylic acid from CPUR_05437 (By similarity).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (By similarity).  The next step is performed by the anthrone oxygenase CPUR_05434 that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving CPUR_05427, CPUR_05428, CPUR_05429 and CPUR_05430 (By similarity).  The short chain dehydrogenase/reductase CPUR_05418 then catalyzes the C-5 ketoreduction to give the xanthone skeleton of the monomeric units (PubMed:32105084).  Ergochromes formation requires further dimerization steps of different xanthone units, probably catalyzed by the cytochrome P450 monooxygenase CPUR_05419 (PubMed:28955461).  CPUR_05425, CPUR_05426 and CPUR_05431 are unique to Claviceps, thus it is likely that they are involved in further modification of xanthone units or in their dimerization (PubMed:28955461).  The yellow ergochromes and the red anthraquinone pigments endocrocin and clavorubin are products from the same PKS derived precursors and the latter are likely shunt products in the pathway of xanthone biosynthesis (PubMed:28955461).  It is proposed that atrochrysone carboxylic acid released from the PKS CPUR_05437 can also be converted to endocrocin anthrone which is further oxidized into endocrocin by CPUR_05435 (By similarity).  Endocrocin could be then modified to clavorubin, possibly by CPUR_05423 and CPUR_05431 (PubMed:28955461).  Clavorubin is the principal anthraquinone metabolite produced by the cluster with a much higher yield compared to endocrocin (PubMed:28955461).
What are the official names of this protein?
Oxidoreductase CPUR_05430, Ergochrome gene cluster protein CPUR_05430.
What is the protein family that this protein belongs to?
Belongs to the avfA family.
Protein: PHNX_HAHCH
Sequence: MSYAYQRFYRGPIEAVIFDWAGTTYDFGSMAPIRAFQNLFAEQEIPITLAEAREPMGTEKREHITRILNMPRVREAWREKYGALASEADIERLYHAFVPMQIEAIRECARPVPGLMETVAWLERRNIKIGANTGYNRDMLDVLTDIAAAQGYRPASNVCATDVPKGRPYPHMSLKNALELGVGDVRACIKVDDTLPGIEEGLAAGMWTVGVTTSGNEVGLSQEDWTALDSASKTVLREQAQERFRRGGAHVIIGSVADLPAAVEYIERWLAQGHGPDTTGLAGVTLTAAGVSLR
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: BIOF_ALIFM
Sequence: MKQAFNQRIRSALNQRKQAGLNRSRRVVSQGNQATLVVDGKSYLNFSGNDYLGLASSKELMEAWQEGLSLYGSGSGASPLVTGYSKPHANLESQLAEWLGFDCAILFNSGFSANQAVLFSLLEKGDTLLQDKLNHASLMEAGMLSPAVMKRFKHNDVGHLKSLLKRSSDEPTLVVTEGVFSMDGDLSPLADIATLTKENDAWLMVDDAHGCGVLGSNGKGCCDVHSITPDILIVTFGKGFGLSGAAVLCNQECGDYLSQFARHHVYSTAMPPAQAHALSHALLMIQQQEWRRDKLKELNQQFESELMNFVGAEKTPTPIKPIIIGEATDAMILADSLKERGLWTTAIRPPTVPVSSARIRVTLSANHSSADISALTQAINELG
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: MRAZ_SALDC
Sequence: MFRGATLVNLDSKGRLTVPTRYREQLIESATGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWYQQVKEDIDAEQSATETLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PRD12_HUMAN
Sequence: MMGSVLPAEALVLKTGLKAPGLALAEVITSDILHSFLYGRWRNVLGEQLFEDKSHHASPKTAFTAEVLAQSFSGEVQKLSSLVLPAEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGRVIAPEHVDICKNNNLMWEVFNEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGTSIFYKAIEMIPPDQELLVWYGNSHNTFLGIPGVPGLEEDQKKNKHEDFHPADSAAGPAGRMRCVICHRGFNSRSNLRSHMRIHTLDKPFVCRFCNRRFSQSSTLRNHVRLHTGERPYKCQVCQSAYSQLAGLRAHQKSARHRPPSTALQAHSPALPAPHAHAPALAAAAAAAAAAAAHHLPAMVL
What is the function of this protein?
Involved in the positive regulation of histone H3-K9 dimethylation.
What are the official names of this protein?
PR domain zinc finger protein 12, PR domain-containing protein 12.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP_RHOPS
Sequence: MRDPVETYMNLVPMVVEQTNRGERAYDIFSRLLKERIIFLTGPVEDGMSTLVVAQLLFLEAENPKKEISMYINSPGGVVTSGLAIYDTMQFIRPPVSTLCTGQAASMGSLLLAAGHKDMRFSLPNARIMVHQPSGGFQGQATDIMLHAQEILNLKKRLNEIYVHHTGQTYKAIEDALERDKFLTAEMAREFGIVDKVIDKRAEETASASGPKAP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIAS_RICCO
Sequence: MFQSRFTILIRTLNSSKSRHFSSTIEPTKPQFPQTLAGLRARLAAESPSLSEFSDLQSNNSYSVEVGTKKKPLPKPKWMREAIPGGDKYVQIKKKLRELKLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPPPDPDEPANVAEAIASWGLDYVVITSVDRDDLPDQGSNHFAQTVQKLKALKPHMLIEALVPDFRGDPGCVENVAKSGLDVFAHNIETVEDLQSVIRDHRANFKQSLDVLMMAKDHAPKGTLTKTSIMLGCGETPEQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVSEYVTPEAFEQYRTXXLVSYVLFSLLISV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SLYA_ECO24
Sequence: MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: MPTA_PYRFU
Sequence: MTIETQEEPPEIKVYLPRVGITNLKSVAKIEWKGRIYTFIPTFEVAIDLPEEKKGIHMSRLVESITETMSEAVEEEVKKVHTSLEDLALCIIRRIEKKHSHKRAEVWIKSTLILERQTPASGKTSYEPYDVEVGVIKNSDGSIKKVLKVKVIGNTACPHAMANNQGKTHIQRAIAELEIETHFNEDIALEDMIEVVESSFSSPTYTLLKTPDENAVVRRMYENPKFVEDVAREIVYKARNRFKGKIHVKVISHESIHKHDVIAEVWA
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: PROP_CAVPO
Sequence: MTAPVQVPQSLLLLLMLLLTLPATGSDPVLCFSQYEDSSSKCKDLLGKDVSLEDCCLNAAYAFKERDNGHCQACRSPRWSPWSSWAPCSVSCSEGSQLRHRRCIGWGGQCSENKAPGTLEWQLQACEEQQCCPEMGGWSNWEPWGPCTVTCSKGTRIRRRVCNNPAPKCGGHCPGVAQESEACDTQQVCPTHGAWGPWGPWSSCLSSCHGGPHKPVETRSRTCSAPEPSKNPPGNPCPGTAYEQQSCAGLPPCPVAGGWGPWGSVSPCSVTCGLGQILEQRKCDNPVPQHGGSFCTGDDTRAHICNTAVPCPVDGEWEPWGDWSTCTRPHLSAIRCKEIVGQQTRVRICKGRKFNGQRCPGKHQEIRHCYNIQNCIFGEKGSWSQWTPWGLCTPPCGANPTRVRQRRCMASLPKFSPTVSVVEGQGEKNVTFWGKPLAQCEELQGQKVLLEEKRPCLHVPACKDPEEEEP
What is the function of this protein?
A positive regulator of the alternate pathway of complement (By similarity).  It binds to and stabilizes the C3- and C5-convertase enzyme complexes (By similarity).  Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (By similarity).
What are the official names of this protein?
Properdin, Complement factor P.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH_PSET1
Sequence: MEKTVEIYTDGSCLGNPGPGGYGIFMIYNEHEKKLSQGYKLTTNNRMEMLGAIVALEVLTRPCVINITTDSQYVKQGIESWITNWKKRGWLTSAKKPVKNVDLWKRLDLACAKHTVTWKWVKGHSGHKYNEIVDDLARDAAGSKDLLDDVGYQP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_ALISL
Sequence: MTQPLIIANTPFSSRLFTGTGKFPNSLIMQQALIESGSELATMALKRVDVSNPEDDILKPIMTAGINLLPNTSGAKNAREAIFAAQLAREALQTNWLKLEIHPDPKYLMPDPIETLKAAEELVRQGFIVLPYCHADPVLCKRLEEVGCAAVMPLGAPIGSNKGIVSRDFLEIIIDQAKVPVVVDAGIGAPSHAAFAMELGADAVLVNTAIAAARNPVAMATAFKLAVQSGRLAYENGLVSVSSQAVASSPLTAFLD
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFA1_UREPA
Sequence: MSHNDKNTHNYQISSLDKIINDSSVAIEFENVYFAYTEERMILKNVSFTINDNEYVCVIGHNGSGKSTISKVLTGLLKPKSGVIKLFGIEISAANLKYLRNNIGIVFQNPDNQFVGITAEDDIAFGLENRKVPPNKMWDIINDAAVATGIEDLLKKESLELSGGQKQRVAIASVLAINPKVIIFDESTSMLDPKGKNELKELMVSLRDVAKKTIISITHDMEEVVKADKVIVMSNGEVQYIGTPQEIFANEERLLKMQLDIPFTLKLAKTLKEKGLKIDLTLNNEELIEKICKN
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MENG_THEVB
Sequence: MTNIQALFERIAPLYDRLNDQLSFGLHHVWKQMAVDWLELPQGATALDLCCGTGDLTRLLARRVGRQGRVVGLDFAAAPLAIARQRSDHYPQIEWLQGDALAVPFAPQTFQGITIGYGLRNVVDIPQALREMFRLLVPGGRAAILDFSHPQTSALEQFQQWYLQQWVVPTARHYGLAAEYDYLWPSIQAFPTPPTLCALIQQAGFERVKHYPLLGGLMAITVAQK
What is the function of this protein?
Methyltransferase required for the conversion of 2-phytyl-1,4-beta-naphthoquinol to phylloquinol.
What are the official names of this protein?
2-phytyl-1,4-naphtoquinone methyltransferase, Demethylphylloquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: Y6532_BACAN
Sequence: MSMEYQERYVRKVATILSSKTKHTTGCLIEGESDVCLEFQIELINALQDNHGLVYHLDFNDYTSETDCLAALKKARKQLRSNKQDGKTLFLSLASFERVEKKTMDAVKILIGSRSLGINLVVSANKRFVHLVGLTEYLVTMNKSDVVLSELYRYSTQKILASLKNENVSWGEANES
What are the official names of this protein?
Uncharacterized protein pXO2-33/BXB0032/GBAA_pXO2_0032.
Protein: GLMM_PASMU
Sequence: MAERKYFGTDGVRGKVGTFPITPDFALKLGWAAGKVLATQGSRTVLIGKDTRISGYMLESALEAGLAAAGLSAAFTGPMPTPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSAQGTKLPDDVEEAIEAMLDEPMDCVESAELGRASRINDAVGRYIEFCKGTFPAHLSLENYKIVVDCAHGATYHIAPNVMRELGAEVIEIGAKPNGLNINEKCGATDIKALQEKVLEVKADVGLAYDGDGDRLIMVDHLGNKVDGDQVLFIIAREALRAGHLKGGVVGTLMSNMSLELALKQLGIPFVRANVGDRYVLEKMQEKGWLLGGENSGHIIILDKNTTGDGIIASLAVLSAMVQHNLSLNELASAVPLFPQVLINVRFAGGDNPLESAAVKAVAAEVEKRLAGKGRILLRKSGTEPLIRVMVECEDGALAQQCAEQIADVVRAN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TF3A_ARATH
Sequence: MAEEAKVDVKTSAKKDIRNYLCQYCGISRSKNYLITKHIQSHHQMELEEERDDEACEVDEESSSNHTCQECGAEFKKPAHLKQHMQSHSLERSFTCYVDDCAASYRRKDHLNRHLLTHKGKLFKCPKENCKSEFSVQGNVGRHVKKYHSNDNRDKDNTGLGDGDKDNTCKGDDDKEKSGSGGCEKENEGNGGSGKDNNGNGDSQPAECSTGQKQVVCKEIGCGKAFKYPSQLQKHQDSHVKLDSVEAFCSEPGCMKYFTNEECLKSHIRSCHQHINCEICGSKHLKKNIKRHLRTHDEDSSPGEIKCEVEGCSSTFSKASNLQKHMKAVHDDIRPFVCGFPGCGMRFAYKHVRNKHENSGYHVYTCGDFVETDEDFTSRPRGGLKRKQVTAEMLVRKRVMPPRFDAEEHETC
What is the function of this protein?
Essential protein (PubMed:22353599).  Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599).  Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599).
What are the official names of this protein?
Transcription factor IIIA, AtTFIIIA.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Accumulates in several nuclear foci including the nucleolus.
Protein: YTCA_ECOK1
Sequence: MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPGWFFCAIASLILTLITRRIIQRTNINLAFVGIIYTALFALYAMLFWLAFF
What are the official names of this protein?
Uncharacterized protein YtcA.
What is the protein family that this protein belongs to?
Belongs to the YtcA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane; Multi-pass membrane protein.
Protein: Y2533_STAHJ
Sequence: MRGGGNMQQMMKQMQKMQKKMAQEQEKLKEERIVGTAGGGMVAVTVTGHKEVVDVEIKEEAVDPDDIEMLQDLVLAATNEAMNKADELTQERLGKHTQGLNIPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SH2533.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GH109_STRMK
Sequence: MFAMKRREFIAASAAVAASSLLPQTPAWARGRKVRLAMIGTGMRGLVLLKELVRRDDVEVVALCDIEPIMLGRAMDMVAKAGKPAPKTYGQDRDTHAWKRLLEQKGIDGVIIATPWEYHAPMAIAAMQAGVAVGCEVVAGITLQDHWDVLKTQLSTGTPYMLLENVCYRRDVMAALQMVRQGLFGELVHLQAGYQHDLRGVKFNSGDPNQPYDSGVEFGPKGWSEARWRTEHSVERNGELYPSHGIGPCAMYTGINRGNRFTHINAFATKARGLHEYTVAKSGGTTHPSTKVKFKLGDIVTTTLACENGETILLQHDTSLPRPYSMGFRVQGTKGLWMDVNHSIHIEGRSPPHQWEEFKKYQDEYEHPLWKQNADTAASAGHGGMDWFVIHAFVEALKAKAPMPIDIYDAVTWSAITPLSEQSIANSFQTLEFPDFTAGAWKQRKPIFAFDGKY
What is the function of this protein?
Glycosidase.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: DPYL3_DANRE
Sequence: MSYQGKKNIPKITSERLLIKGGRIVNDDQSFYADIYMEDGVIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHLQMPFRGTTTADDFTQGTKAALAGGTTMIVDHVIPEPGCSLLEAFDRWSKWADEKACCDYSLHVDITHWNDSVKQEVETLIKEKGVNSFQVYMAFKDLYQMSNTELYEVFTFLGEHGGIAQVHAENGEIIAEEQARMLEMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAADIISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAASFVTSPPLSPDPTTPDYLNTLLASGDLSVVGSAHCTFSVAQKAIGKDDFTQIPEGVNGAEERMSIIWDKAVVTGKMDENMFVAVTSTNAAKILNLYPRKGRIAVGSDSDLVIWDTDAVRTITAKTHHSAAEYNVFEGMELRGAPMLVVCQGKIVLEDGNLHATSGTGRFIPCSPFPDFAYKRVKARKQLAILKAVPRGMYDGPVSEFSPMSRGGTPSASTRTSPTKVPVRNLHQSGFTLSGPEEAPIRPAGRRIVVPPGGRSNITSLS
What is the function of this protein?
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.  Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
What are the official names of this protein?
Dihydropyrimidinase-related protein 3, DRP-3, Collapsin response mediator protein 4, CRMP-4.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, growth cone.
Protein: RBFA_MALP2
Sequence: MKHMSNVKIERYESIIKDLISHAITTLVYDDLIKQATVHYVTLSKDKSIAKVYISCYDKTIIDKILKKINGASGFFRTILAKNLNLRKAPAIVFLNDESIDKIDEINSLLEQIKGK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOC3_DROME
Sequence: MDLQQLEEQARQAALKDIQNMLQRPGQLEKVEQYRHRIARKKASVEALLKTGMQGQLDGVRVGLKQLETCMQDVREVRRRMDEVERLLRGVPEVYDALEVVREENTKHSQYATAMENLKHIFNVDASVQKTMALIEDDKLLNAHQCLADLENSRDDLLYELHKQPKQHASDKITLKRHFEKVDTVSQELEKKLRLILSRTLNTLRKKPTIIVTALRIIEREEKNDQFALQQQKVTGFLPPGRPKAWRRMIMDVLQQSVITRIEGSKLEERADNKMWLVRDLEILRQIILEDLRVVKSLCVPCFPPHYDIFGEYVKFYHEGLSSYLDNIVRSGLEGNEYVSMMAWVTHTYPGVELMSHPDLNVDVHRQIGTLLRPEHLKALEDEYLQNMQRNFQEWMTKAAETEKQEWFTETVPDQDEEYYHTSAPVIIFQMIDQHLQVTNTIHQELTFKALVMSIQQVEIFGQTYLKNVIELKEHHFRNRDQIKYFTHYIITIVNNSQQMVELAQQMKQLYWPKSRTEHYEDFERLLATFQRIRAHAASYLLEEAFLDMECHFNDLFTAKWLASNIAVDTICVTLDDYFQDYNHLRPNNFEMVINEAQKLLAKRYIRALLSKRLSKPRAECDAITRKIKTEAKRFKLFFEKIAPKISLSDSPLDLISTLSALLSSDIELLVLDLHTLLGSYPSLNEDHLVRLFYIRNDVKAAEVREKVQDAMKSKKAMVSIAKQDCIFKEIVFSDKLW
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 3, Exocyst complex component Sec6.
What is the protein family that this protein belongs to?
Belongs to the SEC6 family.
Protein: GMC2_YEAST
Sequence: MSDTTEVPRQSSENDQDNNLERTNSLKSPDVTNNIPSLFKLAAEWQINNPQETFQNHILENDVLKKINEITHLIRESYKDLSSQDGMMSKQQQEKMDWDLFCTVPVNIIEQYTKDMDEIYEKMERLAKQQRLWCESAFQIDVERCGDSILNAETWMKKKERHLEYKNIEMERSANEIKETIQRLTDDR
What is the function of this protein?
Probable transcriptional activator involved in meiotic prophase and synaptonemal complex (SC) assembly.
What are the official names of this protein?
Grand meiotic recombination cluster protein 2.
Protein: HTPG_METFK
Sequence: MSTETLQKETLGFQAEVKQLLQLMIHSLYSNKEIVLRELISNASDAADKLRFEALADNSLYGNDSDLKIRVSFDKQARTITISDNGIGMSREEVINNIGTIAKSGTKEFLQSLTGDQAKDANLIGQFGVGFYSAFIIADKVTLTTRRAGSNEAVRWESTGEGDYTLEPAEKESRGTDIVLHLREGEDEFLNDWKLKSIIRKYSDHITLPIVMKKSEWKDGEQVPTDEDETVNKASALWARNKSDISEQEYQEFYKHVSHDFENPLTWSHNRVEGKQEYISLLYIPSKAPFDLYDRERQHGIKLYVKRVFIMDDAEQLMPQYLRFVRGVIDSADLPLNVSREILQHSKDIEAIKTASVKRVLSMLEDLAENKPEEYAKFWKEFGRVLKEGPGEDFANKERIAGLLRFASTHADTDEQVVSFKDYIARMKEGQEAIYYITADSFAAAKHSPHLEIFRKKGIEVLLLSDRVDEWLVSSLTEFDGKKLQSVAKGDLDLGKLEDEAEKEQQKKTEDEYKPLVERIQAALGDSVKEVRVTHRLTDSPACLVAGEHDLSGNLERLLKAAGQKTPGSKPILEINPDHGIVQRLKDVTDEAKFADWAHLLFDQALLAEGGQLEDPAAFVRRVNAMLA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLAP2_MOUSE
Sequence: MGSLSSRGKTSSPSPSSSGPDQEPVSMQPERHKVTAVALGSFPAGEQARLSLRLGEPLTIISEDGDWWTVQSEVSGREYHMPSVYVAKVAHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGCYSLSVRLSRPASWDRIRHYRIQRLDNGWLYISPRLTFPSLHALVEHYSELADGICCPLREPCVLQKLGPLPGKDTPPPVTVPTSSLNWKKLDRSLLFLEAPASGEASLLSEGLRESLSSYISLAEDPLDDA
What is the function of this protein?
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling.  Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells.  May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
What are the official names of this protein?
Src-like-adapter 2, Src-like adapter protein 2, SLAP-2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cytoplasmic vesicle. Late endosome. Note=Localized to the plasma membrane and intracellular vesicles, including late endosomal vesicles.
Protein: KHSE_YERPE
Sequence: MVKIYAPASIGNVSVGFDVLGAAVSPIDGTLLGDCVSVTAAERFSLHNEGRFVSKLPDDPKQNIVYQCWERFCQEMGKEIPVAMVLEKNMPIGSGLGSSACSVVAGLMAMNEFCGQPLDKVTLLGMMGELEGRVSGSIHFDNVAPCYLGGMQLILEQEGYISQDVPGFSDWLWVMAYPGIKVSTAEARAILPAQYRRQDCITHGRNLAGFIHACHTQQPDLAAKMMKDVIAEPYRTQLLPGFAAARQAAQDIGALACGISGSGPTLFAVCNDQATAQRMAGWLQNHYLQNDEGFVHICRLDTAGARLLG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_DELAS
Sequence: MTKAAELRQKDVAGLEAEVKSLQKAHFGLRMQKATQQLGNTNTLRTTRRDIARAKTILAEKQAAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GPMB_SALPA
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVGERARSLGITHIISSDLGRTKRTAEIIAQACGCDITFDSRLRELDMGVLEKRQIDSLTEEEEGWRRQLVNGTQDGRIPGGESMQELSDRVHAALASCLELPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRIDYQESQWLASGWVVETAGDVSHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: RECA_STRMU
Sequence: MAKRIKKTEEITKKFGDERKKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIVEIYGPESSGKTTVALHAVAQAQKDGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGIMFGNPETTPGGRALKFYSSVRLDVRGNTQIKGTGEQKDSNIGKETKIKVVKNKVAPPFKEAFVEIIYGEGISRTGELVKIASDLGIIQKAGAWYSYNGEKIGQGSENAKKFLADNPEIFDDIDHKVRVQYGLIEEDNTEEKQSSKEKETDEKADKNLVLELDDTIELED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.