PharMolix/UniProtQA huggingface dataset:
Protein: END4_ECO27
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVAEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RELB2_METJA
Sequence: MSIVQSYITDEKGNIKGVILDYKTFKKIEELLLDYGLLKAMEEVENEEEIDLETAKKLLEQ
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is RelE2 (Potential).
What are the official names of this protein?
Putative antitoxin RelB2.
Protein: EFTU_CHLTB
Sequence: MSKETFQRNKPHINIGTIGHVDHGKTTLTAAITRTLSGDGLADFRDYSSIDNTPEEKARGITINASHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGAMPQTKEHILLARQVGVPYIVVFLNKIDMISEEDAELVDLVEMELAELLEEKGYKGCPIIRGSALKALEGDAAYIEKVRELMQAVDDNIPTPEREIDKPFLMPIEDVFSISGRGTVVTGRIERGIVKVSDKVQLVGLRDTKETIVTGVEMFRKELPEGRAGENVGLLLRGIGKNDVERGMVVCLPNSVKPHTRFKCAVYVLQKEEGGRHKPFFTGYRPQFFFRTTDVTGVVTLPEGVEMVMPGDNVEFEVQLISPVALEEGMRFAIREGGRTIGAGTISKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_BACC1
Sequence: MGYNAGSYDVIVIGAGHAGCEAGLAAARMGSKTLMLTINLDMVAFMPCNPSVGGPAKGIVVREIDALGGEMGRNIDKTHIQMRMLNTGKGPAVRALRAQADKFSYQHELKKTIEETPNLTLFQGMVERLIVEDGECKGVITQAGAEYTAKTVVITTGTFLRGEIIMGDLKYSSGPNNQQPSITLSEHLEELGFDLVRFKTGTPPRVNSNTIDYSKTEIQPGDDKPRAFSFETTKFIMDQIPCWLTYTSTETHRLIDENLHRSAMYSGMIKGTGPRYCPSIEDKVVRFNDKPRHQIFLEPEGRNTQEVYVQGLSTSLPEDVQRDMLRTIPGLENVEMMRTGYAIEYDAIVPTQLWPTLETKKIKNLYTAGQINGTSGYEEAAGQGLMAGINAACRSLGKKEVILGREDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTEIGHEIGLIKEERYERFTNKKLQIEQEKERLSSIIIKPRPEVQELIRNIGGSELKDGIRASDLLRRPEMTYEHIHLLVPSEVELSDEVTEQVEIQIKYEGYIEKSLQQVERMKKMESKKIPVDIDYDAISSLASEARQKLKDVRPLSVGQASRISGVNPADISILLVYIEQGKIARVSNQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_XYLFT
Sequence: MNKHASLIHPTAVIAPSATLAPDVQIGAFTLIGNDVQIDTGTIIGSHCTIHGPTRIGRNNRFIGQAAIGGEPQDKKFAGERTELLIGDNNTIREFVTINRGTGGGGGVTSIGNDNWILAYTHIAHDCHVGHHCVFSNNASLAGHVTVGDWVIFSGFSGAHQFCRIGRYAFIGMGTLINGDVPPFTLIGSDTLGRPRGINNEGLKRRNFTPERITAIKRAYRTLYVAGLPLAEAKQQLAEQAKDNDDIKELLQFIETAQRPLLR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2261_LISIN
Sequence: MSEDKGMKDKAKGLKDKVVGDAKDKFGKATDDKGKQVEGKAQKAKGEVEDKTGDAKKKLSE
What are the official names of this protein?
UPF0337 protein lin2261.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: IMSP5_RUDPH
Sequence: MILVVTLACLIAVVCCQCPTTDQGQISKVFKAYDIDGNNKISRVEGTMVFRDADLNRDGALDNNEFSSEWAFYHNDYYSPFFNVADRNHNGRIEFVEGNQGFDHFDKNRDNEISSWEFTQTWMETVRPSSRPIDF
What are the official names of this protein?
Insoluble matrix shell protein 5, IMSP5.
What are the subcellular locations of this protein?
Secreted.
Protein: ANR45_HUMAN
Sequence: MESEGPPESESSEFFSQQEEENEEEEAQEPEETGPKNPLLQPALTGDVEGLQKIFEDPENPHHEQAMQLLLEEDIVGRNLLYAACMAGQSDVIRALAKYGVNLNEKTTRGYTLLHCAAAWGRLETLKALVELDVDIEALNFREERARDVAARYSQTECVEFLDWADARLTLKKYIAKVSLAVTDTEKGSGKLLKEDKNTILSACRAKNEWLETHTEASINELFEQRQQLEDIVTPIFTKMTTPCQVKSAKSVTSHDQKRSQDDTSN
What is the function of this protein?
May play a role during cell division.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 45.
What are the subcellular locations of this protein?
Cytoplasm. Midbody, Midbody ring. Cleavage furrow. Note=Distribution is highly dynamic during mitosis. Not detected during interphase, localized to cytoplasm during metaphase, to cleavage furrow during anaphase and telophase, and to midbody ring during cytokinesis.
Protein: RS8_OCEIH
Sequence: MVMTDPIADMLTRIRNANMVKHEKLELPASNIKKEIADILKREGFVKDYELIEDNKQGVLRIFLKYSANEDKVISGIKRISKPGLRVYAKADEVPRVLNGLGIAIVSTSNGLLSDKEARSQAVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: COX1_LOCMI
Sequence: MTQKWLFSTNHKDIGTLYFMFGAWAGMVGTSMSMIIRAELGQPGTMINDDQLYNVIITAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLTLLLMSSVVDNGAGTGWTVYPPLASVIAHSGASVDLAIFSLHLAGVSSILGAINFITTAINMRSNNMTLDQTPLFVWSVAITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHIVCQESGKIESFGTIGMIYAMLSIGLMGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTGIKVFSWMATLYGTKFKFNPPLLWALGFIFLFTMGGLTGLVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGIIQWYPLFTGLTMNSKWLKIQFTIMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTSWNVISSIGSTISITGIIMFILIMWESMIKQRNVFIWTNMSSSTEWLQNNPPAEHSYSELPLINL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LV1A2_LYCMC
Sequence: MNIMLFCSVFILVSLTGLSVSDDVPGNYPMSLYGNKYSCGVLGENEYCRKICKSHGVNYGYCFNSRCWCEYLEDKDVDFWAAHKNHCKNGKLYPPKK
What is the function of this protein?
The edited BmKBTx-like, similar to beta-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv).
What are the official names of this protein?
Lipolysis-activating peptide 1-alpha chain, LVP1-alpha.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YQGF_ECO57
Sequence: MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNLIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVEARSGLFEQGGYRALNKGKIDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A16L2_HUMAN
Sequence: MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ
What is the function of this protein?
May play a role in regulating epithelial homeostasis in an ATG16L1-dependent manner.
What are the official names of this protein?
Protein Atg16l2, APG16-like 2, Autophagy-related protein 16-2, WD repeat-containing protein 80.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ATG16 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Localizes also to discrete punctae along the ciliary axoneme.
Protein: BM8A_BOMMX
Sequence: MKCFAQIVVLLLVIAFSHGAVITGVCDRDAQCGSGTCCAASAFSRNIRFCVPLGNNGEECHPASHKVPYNGKRLSSLCPCNTGLTCSKSGEKFQCS
What is the function of this protein?
Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia.  Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons.  At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12.  In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal (GI) smooth muscle (nanomolar concentration).
What are the official names of this protein?
Prokineticin Bm8-a, Prokineticin Bv8-like peptide 1, Bv8-LP1.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PNP_SHEPC
Sequence: MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKEAEAGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSEDETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPQIEPDIISMIGTSAALAISGIPFSGPLGAARVGYINGEYVLNPTVAQIETSQLNLVVAGTASAVLMVESEAQALPEEVMLGSVVYGHDQQQVVINAIAEFKAEAGKPMWDWTAPVQDETLVAQIKELAEAGLGDAYKIQVKQDRYAQVAVVKAATKEALLASNPNIDLREVDNLLGSLEKKVVRGRIIRGEPRIDGREPDMIRALSVLAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKIDSIMGERTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGINAVMPSAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRGGITALQMDIKIEGITKEIMEIALQQAYGARVHILNVMDQAIGSHRDDISDHAPRITTIKINPEKIRDVIGKGGAVIRALTEETGTTIELEDDGTVRIASSNGEATKEAIRRIEEITSEVEVGRIYNGKVIRIVDFGAFVNILPGKDGLVHISQISDERVANVSDHLELNQEVAVKVMEVDRQGRVRLSIKEAQTKEAAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S12A7_HUMAN
Sequence: MPTNFTVVPVEAHADGGGDETAERTEAPGTPEGPEPERPSPGDGNPRENSPFLNNVEVEQESFFEGKNMALFEEEMDSNPMVSSLLNKLANYTNLSQGVVEHEEDEESRRREAKAPRMGTFIGVYLPCLQNILGVILFLRLTWIVGVAGVLESFLIVAMCCTCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEIFLTYISPGAAIFQAEAAGGEAAAMLHNMRVYGTCTLVLMALVVFVGVKYVNKLALVFLACVVLSILAIYAGVIKSAFDPPDIPVCLLGNRTLSRRSFDACVKAYGIHNNSATSALWGLFCNGSQPSAACDEYFIQNNVTEIQGIPGAASGVFLENLWSTYAHAGAFVEKKGVPSVPVAEESRASALPYVLTDIAASFTLLVGIYFPSVTGIMAGSNRSGDLKDAQKSIPTGTILAIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKANGEPTWALLLTVLICETGILIASLDSVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMSLCLALMFICSWYYALSAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALLRVEHGPPHTKNWRPQVLVMLNLDAEQAVKHPRLLSFTSQLKAGKGLTIVGSVLEGTYLDKHMEAQRAEENIRSLMSTEKTKGFCQLVVSSSLRDGMSHLIQSAGLGGLKHNTVLMAWPASWKQEDNPFSWKNFVDTVRDTTAAHQALLVAKNVDSFPQNQERFGGGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQVDDNSIQMKKDLQMFLYHLRISAEVEVVEMVENDISAFTYERTLMMEQRSQMLKQMQLSKNEQEREAQLIHDRNTASHTAAAARTQAPPTPDKVQMTWTREKLIAEKYRSRDTSLSGFKDLFSMKPDQSNVRRMHTAVKLNGVVLNKSQDAQLVLLNMPGPPKNRQGDENYMEFLEVLTEGLNRVLLVRGGGREVITIYS
What is the function of this protein?
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:10913127).  May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear.  Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti.  May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity).
What are the official names of this protein?
Solute carrier family 12 member 7, Electroneutral potassium-chloride cotransporter 4, K-Cl cotransporter 4.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL27_BRASB
Sequence: MAHKKAGGSSRNGRDSKGKRLGIKAFGGERVIPGNIIARQRGTTWHPGLNVGMGTDHTLFAKIEGVVEFHARANRTFISVRPVAAQAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SCPA_BACCZ
Sequence: MQYNFKVEAFEGPLDLLLHLIHRYEIDIYNIPVAEITEQYLSYVHTMKELQLDVASEYLVMAATLLQIKSKMLLPKHEEDVLDNGDDFIDDPRQELMERLIEYKKYKQVATELKEREQERAQLYTRPPIDFTSLQQEEETNLPLDVTLYDMLAAFQKLMRRKKAKKPVTTRITRQEIPIEQRMTDILKQLEIQGGRQSFYDLFVDDEREIMVVTFLAVLELMKNQQIIIEQEHNFDEIFVSSYTKSA
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: PYRG_PSEAB
Sequence: MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKITMLKLDPYINVDPGTMSPFQHGEVFVTQDGAETDLDLGHYERFVRTTMTQNNNFTTGRVYMDVLRKERRGDYLGATVQVIPHITDEIKRRIIKGAGDADVALVEIGGTVGDIESQPFLEAIRQLRVEIGAKRAMLMHLTLVPYIATAGETKTKPTQHSVKELRSIGLQPDVLVCRSDHPIDVSSRRKIALFTNVEERAVIALEDVDTIYRIPSVLHAQGLDDIVVERFGLECGQADLSEWDRVVDAKLNPEREVTIAMVGKYMELLDAYKSLIEAMTHAGIQSRTKVNLRYIDSEDIEQQGTSLLEGVDAILVPGGFGLRGVEGKISTVQYARENKIPYLGICLGMQVAVIEYARNVLGWSDANSTEFDKSSGHPVVGLITEWQDATGATEIRTEASDLGGTMRLGAQECQLQTGTLVHDCYAKDVIVERHRHRYEVNNNLLPQLEQAGLKISGRSGDGALVEVVEAPEHPWFVACQFHPEFTSTPRDGHPLFSGFVNAALKYSGKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: VPS72_XENLA
Sequence: MNLADGRAPRKTAGNRMSGLLQAEEEDDFYKTTYGGFNEESGDEEYNEDRSASEDEVDSDFDIDEGDEPTSDHEEDEPKKKRRVVTKAYKEPIQLLKPKPKKPEAPPNTAAKSRPEKPQEPPDDTVDSRKQMRQSTTEHTRQTFLRVKERQIQSKKKKGPHLDRPLTQEELLEEAKITEEINIRSLENYERLEADRKKQVHKKRRCAGPTIRYHSMVMPLITELRMKEENVDVEGLDHEQTDRTHAGKCSRSFITFSDDETFERFFPRSKRGKFSVRDVCPVTHKPALYRDPITDIPYYNSKAFKIIRDAYKKYITTHGLPNAAMATTMGPSADAAQRNTRQKIIIKQSVPSA
What is the function of this protein?
Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes.  As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 72 homolog, Transcription factor-like 1.
What is the protein family that this protein belongs to?
Belongs to the VPS72/YL1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTG8R_HUMAN
Sequence: MAKESGISLKEIQVLARQWKVGPEKRVPAMPGSPVEVKIQSRSSPPTMPPLPPINPGGPRPVSFTPTALSNGINHSPPTLNGAPSPPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDISPEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTSIASPADSSELLMEVHGNGKRPSPERREENSFDRDTIAPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPNKMLEHREVRDRHHSLGLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRYNENTELRKTGTELVSRQHSPGSADSLSNDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL
What is the function of this protein?
Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199).  Via association with PRDM14 is involved in regulation of embryonic stem cell (ESC) pluripotency (PubMed:27281218).  Involved in primordial germ cell (PCG) formation.  Stabilizes PRDM14 and OCT4 on chromatin in a homooligomerization-dependent manner (By similarity).  Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453).  May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 (AML1-MTG8/ETO fusion protein) which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21).  May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth.  May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.  Through heteromerization with CBFA2T3/MTG16 may be involved in regulation of the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes (By similarity).  Required for the maintenance of the secretory cell lineage in the small intestine.  Can inhibit Notch signaling probably by association with RBPJ and may be involved in GFI1-mediated Paneth cell differentiation (By similarity).
What are the official names of this protein?
Protein CBFA2T2, ETO homologous on chromosome 20, MTG8-like protein, MTG8-related protein 1, Myeloid translocation-related protein 1, p85.
What is the protein family that this protein belongs to?
Belongs to the CBFA2T family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS8_YERPP
Sequence: MSMQDPIADMLTRIRNGQAANKVAVTMPSSKLKVAIANVLKEEGFIEDFKIEGDTKPVLELALKYFQGKAVVESIQRISRPGLRIYKKKDELPKVMAGLGIAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: YICR_SALNS
Sequence: MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLAKEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLSPEMTREFLQSQLTCEEREIFLVIFLDAQHRVLQHSRLFSGTLNHVEVHPREIVREAIKLNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: SELO_NITMU
Sequence: MSQSNLQRSMPIVTLPDLFDARFDNRFVRQLPGDPETRNVPRQVRNAGYTQVSPTPVRSPRLLAWADEVGEMLGIARPASPVSPAVEVLAGNRILPSMQPYAARYGGHQFGHWAGQLGDGRAITLGELISPNDKRYELQLKGAGKTPYSRTADGRAVLRSSVREFLCSEAMHSLGVPTTRALSLVATGEAVIRDMFYDGHPGAEPGAIVCRVSPSFLRFGNFEILAAQKEPELLRQLADFVIGEHFPELASSHRPPEVYAKWFEEVCRRTGILVAHWMRVGFVHGVMNTDNMSILGLTIDYGPYGWLEGFDLHWTPNTTDAQGRRYCYGNQPKIAQWNLTRLAGALTPLIEDDAALEHGLAVFGETFNNTWSGMLAAKLGLASLEHSDDDSLLSDLFETLQQVETDMTLFFRCLMNIPLNPISGNRATTFPAPENLESVDQMNDHGLVELFRPAFYDAHQAFSHAHLTRLAGWLRRYIARVRQEGEPEGLRYHRMSRANPKYVLRNYLAQQAIEALERGDDSVIIRLMEMLKHPYDEQPEHEDLAARRPEWARNKPGCSALSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: OBG_RICRS
Sequence: MHFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYRYKQHFTAENGENGKDSNRSGKSGKSLVLDVPIGTQIFSEDGNILFYDFTVDDQSFEIIKGGSGGLGNSHFKSSVNQAPRKRTEGEIAEEMWIHLSLKLLSDVGLVGLPNAGKSTFLSVVTAAKPKIADYPFTTLVPNLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVLIHLIDGSSNDVVADYNTVRLELESYSDYLKNKIETICLNKCDVLTDEEIQEKINKLQKVTNKEVFPISTCTNAGVNKIVKLALETIKNQE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGS10_HUMAN
Sequence: MFNRAVSRLSRKRPPSDIHDSDGSSSSSHQSLKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTAAKRASRIYNT
What is the function of this protein?
Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2.  Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541).  Modulates the activity of potassium channels that are activated in response to CHRM2 signaling (PubMed:11443111).  Activity on GNAZ is inhibited by palmitoylation of the G-protein (PubMed:9353196).
What are the official names of this protein?
Regulator of G-protein signaling 10, RGS10.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm, cytosol. Nucleus. Note=Forskolin treatment promotes phosphorylation and translocation to the nucleus. SUBCELLULAR LOCATION: Nucleus.
Protein: Y3390_BACC1
Sequence: MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAGVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDEHAS
What are the official names of this protein?
UPF0316 protein BCE_3390.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.