PharMolix/UniProtQA huggingface dataset:
Protein: NANF_ASPNN
Sequence: MTVDDSLSPAGVATPHSSGIRVVVVGLGIAGLTTAIECHRKGHTVIALEKSPVIRVLGDSLGLGSNATNVLEKWADGKILQQLKSLADDISIFEALDSAGKLYAKDDAKGFGADNGMIINRGSLATTLHEYAKMLEIDIRFGAAVTGHWEDESAAGVIINGEQRLVADCVIGCDGIHSKTREAVLTKEPTAVPSGQAVFRASFDSTSVCNDPNARWILAEKGVRDRLSQYMAEGGLALSLATGKRGQNITWQLWHEDNHNANELWSEHNSAKLENALGMIRHWPIYSKVVPILRHTPKEALTDFKLVNRAALPTWISHAGRIIIIGDAAHPVLPIVGQGGGQGIEDAATVAICLQLAGKTHISLALQAVERLRYARTSIIQSSGPKIYAGVRNPDWKAIEKDPSLIMLPRPKWIFGYDVPRDVYEQFPLVKRAIEEGSSYTPKNIPPGGRYEFLHDFKE
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the benzazepine alkaloid nanangelenin A which contains an unprecedented 3,4-dihydro-1-benzazepine-2,5-dione-N-prenyl-N-acetoxy-anthranilamide scaffold (PubMed:32182055).  The first step of nanangelenin biosynthesis is catalyzed by the indoleamine 2,3-dioxygenase nanC which produces N-formyl-kynurenine through the catabolism of tryptophan (PubMed:32182055).  The two-module NRPS nanA then utilizes anthranilate (Ant) and L-kynurenine (L-Kyn) to assemble the dipeptide product nanangelenin B (PubMed:32182055).  The first adenylation domain of nanA (A1) loads anthranilate onto the T1 domain, while A2 loads kynurenine, generated through spontaneous nonenzymatic deformylation of the nanC-supplied N-formyl-kynurenine (PubMed:32182055).  The peptide bond formation between the tethered amino acids is catalyzed by the first condensation domain (C1) between anthranilate's carbonyl carbon and kynurenine's aliphatic primary amine (PubMed:32182055).  The second C domain (C2) catalyzes the final cyclization event between the aromatic amine of kynurenine and the tethered carbonyl carbon, yielding nanangelenin B (PubMed:32182055).  The terminal T3 domain enhances the catalytic efficiency of C2, suggesting the T2-tethered Ant-L-Kyn is transferred to T3 prior to cyclization by C2 (PubMed:32182055).  Once released from nanA, nanangelenin B is then prenylated by the prenyltransferase nanD to form nanangelenin C (PubMed:32182055).  Nanangelenin C is then N-hydroxylated by the FAD-dependent monooxygenase nanF and further acetylated by the acetyltransferase nanB to yield nanangelenin F (PubMed:32182055).  Finally, the N-methyltransferase nanE methylates the amide nitrogen of 1-benzazepine to convert nanangelenin F into nanangelenin A (PubMed:32182055).  NanE is also able to methylate most of the intermediates of the pathway such as nanangelenin B and nanangelenin C to produce nanangelenin D and nanangelenin E, respectively (PubMed:32182055).
What are the official names of this protein?
FAD-dependent monooxygenase nanF, Nanangelenin A biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: GRPE_THET2
Sequence: MEERNHENTLEKDLEAVGQEAQALEERLKAAEEELKGLKDKYLRLLADFDNYRKRMEEELKAREREGVLKALRALLPVLDDLDRALEFAEASPESIRQGVRAIRDGFFRILAGLGVEEVPGEGEAFDPRYHEAVGLLPGEPGKVAKVFQRGFRMGEALVRPARVAVGEEKQEEADLE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_ROSS1
Sequence: MDYLVTIGLEIHAQILTRSKMFCGCSADYADAPPNTHVCPVCMGLPGALPTPNRRAIELAALTGLALNCRISHTNVISRKNYFYADLPSGYQRSQYDDPLCVDGWVEIEGDSGPKRIRLTRVHIEEDTGKLIHTNDGGSLVDFNRAGVPLMEIVSKPDISSPEEARRYFQKLRQILVWIGVNSGDMESGALRCDANVSVRPAGQQEYGAKVEIKNINSFRFVERALAYEIERQIRALKAGEPIVQSTRGWDEVSGTTVAQRTKEFAEDYRYFPEPDIPPLHLTDAWIDERRAELPELPDARRIRFIEEYGLTAYDAGVLTDERTVSDYYEQAVAAARTRGVMPKEVANWLTGEFFRLLKETGESPAHAAQRMRPEYIGEVQELLNNGVITRTSAKEAFEAAFREGRSPAVIVAERGLAVIGAGDALTDLVRQVIAGNPKVVEEYRRGKATAIKYLIGQVMKATRGQANPQAVQQALEQELAREQAAC
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: GCH1_STRP6
Sequence: MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKMYAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRGIKKPGSKTITTTARGLYKESRAERQEVISLMTKD
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: NUSB_METI4
Sequence: MISRRKIRELIVQFLYQWEMNKGVGLDNMLLDFWDFSPLDQKDKEAVEQWLKEIAEHKEAIEEKINSYVKNWSLDRLAPVDKCILILGIYEILYRKDIPPAVSINESVEIAKKYSTEESGKFVNGILDSVLKDSGRKAWMSCP
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: DNAK_GLUOX
Sequence: MSKVIGIDLGTTNSCVAVREGDETKVIENSEGARTTPSMVAFTDNGERLVGQAAKRQAVTNPANTLYAVKRLIGRRYDDPTVQKDKEMVPYAIVRGDNGDAWVEARGEKYAPSQIAAYVLGKMKETAESYLGETVSQAVITVPAYFNDAQRQATRDAGKIAGLEVLRIINEPTAAALAYGLGKRDSGTVAVYDLGGGTFDVSILEISDGVIEVKSTNGDTFLGGEDFDNRIIGFLADEFKKDQGIDLRGDKLALQRLKEAAEKAKIELSSSKETEINLPFITADASGPKHLVVKLSRAKLESLVDDLIQRTLGPCRAAIKDASVSANEIDEVILVGGMTRMPKVIETVKEFFGKDPARNVNPDEVVAIGAAVQGAVLKGDVKDVLLLDVTPLSLGIETLGGVFTRLIDRNTTIPTKKSQTFSTAEDNQNAVTIKVYQGEREMAADNKLLGNFDLQGIAPAPRGVPQIEVTFDIDANGIVNVSAKDKATNKEQQIKIQASGGLSDADIDRMVKDAEANASADKAKRELVELRNSTESLIHQTEKSITEGGDKVPAADKSEAEAAIAEAREALGGENLDTLKAASEKLTQAAMKVGQGVYQAGQGAEGGAAPEGEKKDENVVDADFEDLEDDSKKH
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YCIB_ACTP2
Sequence: MKQLLEFIPLILFFTVYKLYGVQQAAITLVIATVIQLIVLKVLYKKIEKSQWIMGIFAVFFGILTAYFNDLNFLKWKVTIINGLFAAVLLVSQFVFKKPIIQMLLGKELKLPTNVWNRLNLGWAGFFIICMLLNIVISYYFSDDVWATFKTFGFTGLSLIAAIATGVYLYPHLKNVENTNEQA
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEUD_ECOSE
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: MSRQ_SHIFL
Sequence: MRLTAKQVIWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLAALLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQSMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSLFNRLRKQAHNKLSL
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TILS_SYNP6
Sequence: MSSDCWTPFHARLHQLLQRRSLLPTRSRLLLAVSGGQDSLALVQLLRGLQPHWHWSLAIAHCDHGWRSDSTANAEHLRQLADQWQLPFYCQRSPEPPRSEAAARTWRYQVLEAIAADIDAALLVTGHTASDRAETLLYNLTRGSHLQGLASLRWQRSLSDRLTLVRPFLGFTRAETSKMVQQFQLPVWEDSTNRDRRFARNRLRLEVLPQLRQINPQCDRHLANTAELLADEADWLAELTEQVYQQSLSERGLCRSQLAQQPIALQRRVLHAFLQDQLQRSPSTVQVEELRQLITAPQGSCSSSLPQRRVAVVAGDWLRLQSVDD
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSN3_ASPTN
Sequence: MYGRNFPFFNSLGGFYPRGNGFPLDAPSLDPRKPSGTGYTSKVRVRDKYRIVGFISSGTYGRVYKAIGKNGEKREFAIKKFKPDKEGEIIQYTGLSQSAIREMSLCSELDHPNVVQLEEIILEDKCIFMVFEYTEHDLLQIIHHHTQPQRHAIPAPMVRSILFQLLNGLLYLHTNWVLHRDLKPANILVTSSGAIRVGDLGLARLFYKPLNSLFSGDKVVVTIWYRAPELLMGSRHYTPAVDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMMKIIEIMGLPTKEIWPGITSMPEFSQLQSLAMSRAPHFNRSSNLENWYQSCLKNGGYSANSSAGTPGADGFDLLSRLLEYDPTKRITAREALEHPYFKNGGPISANCFEGFEGKYPHRRVTQDDNDIRSGSLPGTKRSGLPDDSLMGRASKRIKE
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase ssn3, Cyclin-dependent kinase 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TR2M_PANAY
Sequence: MKPHSVFADSLWPSIDLLYDYAPFLQQSMVDGHIGFFPTGITPPRVAIIGAGISGLIAATELLRAGVRDITLFEARDRLGGRAWSQLFDPHYYPRLIAEMGAMRFPPSATGLFHYLNRFSIQTSASFPDPGIVDTELHYRGVRHLWPAGEQPPALFTRVHNGWRALLYEGCLLDGVSLVGPLQITAMLKSERFDEAAEAWQIWLNVFRDCSFYSAMVTIFTGTNPPGGIAWERRDDFELFGALGIGSGGFLPVYQAGFTEILRMVINGYEDDQRLIIGGISTLAEQLARQEIRGTTPGRHVRFSKVNRISKDNGKISLATDVKPVDAFDRVIVTSNNRAMQMVHGLSADETFLNQDVCRAVRETHLTGSSKLFMLTRDKFWLKNKLPLTIQSDGLVRGVYVLDYESDNPEGRGVVLLSYTWEDDAHKLLAITDKKQRGQHLVDELSAIHPEFARYLVPAGADYERYVLHHDWLTDPCSAGAFKLNYPGEDVYSQRLFFQFKTANHPEQDSGLLLAGCGCSFTGGWVEGAVQTAVNSACAVIRSTGGTLYGNPLDSVHSIYDY
What are the official names of this protein?
Tryptophan 2-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2-monooxygenase family.
Protein: RLMA_ECOLI
Sequence: MSFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKRSRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRERLDDKATAVLDIGCGEGYYTHAFADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCKAEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQQSAELCYPMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRSY
What is the function of this protein?
Specifically methylates the guanosine in position 745 of 23S rRNA.
What are the official names of this protein?
23S rRNA (guanine(745)-N(1))-methyltransferase, 23S rRNA m1G745 methyltransferase, Ribosomal RNA large subunit methyltransferase A.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmA family.
Protein: LPXC_BURTA
Sequence: MLKQRTIKSIVKTVGIGLHSGRKVELTLRPAAPDTGIVFSRVDLPTPVDIPASALSIGDTRLASVLQKDGARVSTVEHLMSACAGLGIDNLYVDVTAEEIPIMDGSAASFVFLIQSAGIEEQNAAKKFIKVTKPVEIRDGDKFARLDPYFGFKLKFTIDFRHPAVDKTGQELEVDFANTSYVREIARARTFGFAHEVEMMRELGLARGGSMDNAIVLDEYRILNNDGLRYDDEFVKHKMLDAIGDLYVVGHPLLASYTAYKSGHGLNNALLRELLAHEDAYEIVTFDDPKAAPTGFGFDAQTAFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PURL_THEVB
Sequence: MSQTPLVTEAEITAEGLKPQEYTEIVRRLGRHPNRAELGMFGVMWSEHCCYKNSRLLLKQFPTQGPRVLVGPGENAGVVDLGDGLRLAFKIESHNHPSAIEPFQGAATGVGGILRDIFTMGARPIALLNALRFGDLKEAKTQQLVKGVVAGIAHYGNCVGVPTVGGEVYFDPCYAGNPLVNAMALGLMETPEIVKSAASGIGNPVLYVGSTTGRDGMGGASFASAELTDESMSDRPAVQVGDPFVEKCLIEACLEAFQTGAVVAAQDMGAAGLTCSTSEMAAKGGVGIELDLDKVPVREQGMVPYEFLLSESQERMLFVAAQGREAELIEIFQRWGLQAVVVGRVIAEPLVRVLYRGEVAAEVPARALAEETPLYERECPKEPPAYVQQARQWSVDQLPLPARSPAEILLTLLATPSIASKAWVYRQYDHEVQNNTLVFPGDGDAAVIRLRGTAKGIAATVDCPSRYVYLDPYEGGKAAVAEAARNLSCVGAEPLAVTDNLNFGSPETPVGYWQLANACRGLAEACRALQTPVTGGNVSLYNETIDSNGQPQPIYPTPVVGMVGLIADLQRVVGQGWRATGDAIYLLGLPLTTPLSDPRLSLGGSEYLAQIHGLVAGCPPQIDLDLEQRVQAVCRYGIQQGWIASAHDLSEGGLAVALAESCLSGQRGATIQLPEGTYPRWDALLFAEGGARILVSVPPREQVAWEAYAQAQLPNAWTRLGVVNGEDTELCIDSCNNSPLIRVTIKELDLAWRSPLPKYLD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_CHLFF
Sequence: MSKRITRVLFKISGESLSTDSGNRIDEVRLSRLVAELRAVRNCDIETALVIGGGNIIRGLAQQKELQINRVSADQMGMLATLINGMAVADALKADDIPCLLTSTLSCPQLADLYTPQKSAEALSQGKVLICTTGAGSPYLTTDTGAALRACELKADLLLKATMHVDGVYDKDPREFSDAVKYNRISYKEVLSRGLGIMDASAISLCMDSHIPIRVFSFVKHSLEQAIFDEHIGTLICEDA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y393_IDILO
Sequence: MQLIIVSGRSGSGKTIALRVLEDLGFYCVDNLPISLLPTLVHAVIEQYQKIAISIDVRNLPEHSEELLDSLSFLPKGVEPEILFIDSDDNTLLKRFGETRRLHPLSQKELPLLEALQAEHKMLEPIMERATWRLDSSDLSLHQLSEQVTERVLGRADKKLIIVFQSFGFKYGLPKDADFVFDARILPNPHWQPELKLLTGLDTDVQIFFRQEPLVTKFIYQLENFLDTWLPHFQRSNRSYLTIATGCTGGQHRSVYISQQLAERFEQKAVKVQVRHRELKTHG
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein IL0393.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RS10_RHIEC
Sequence: MNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRSPHIDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SPX_STRA3
Sequence: MITLFLSPSCTSCRKARAWLSKHEVAFEEHNIITSPLNKEELLQILSFTENGTEDIISTRSKVFQKLAIDVDELSTSSLMELISENPSLLRRPIILDKKRMQIGFNEDEIRAFLPRDYRKQELKQATIRAEIEGKHD
What is the function of this protein?
Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes.  Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP).  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
What are the official names of this protein?
Global transcriptional regulator Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXBD_BACSU
Sequence: MNIIPTCQVPKDLVSAFFQKHWGSPQMVISSGIYNCDELDGYGMLNDDNQIVGLITYIFEEDACEIISLDSVIENKGIGTALLEKAEEACRERNIKQIKLITTNDNIHALAFYQKRGYRLDRLFVNAVETARKMKPEIPLLADNKIPIRDELLLVKELQ
What are the official names of this protein?
Uncharacterized protein YxbD.
Protein: FOLD_ECO24
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ATPL_MYCGI
Sequence: MDPTIAAGALIGGGLIMAGGAIGAGIGDGIAGNALISGIARQPEAQGRLFTPFFITVGLVEAAYFINLAFMALFVFATPVG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZIC2_MOUSE
Sequence: MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPPEQHGPHASQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGAGSGSSGSGGGSAAGSGGGGGGAGGGGGGSSGGGSGTTGGHSGLSSNFNEWYV
What is the function of this protein?
Acts as a transcriptional activator or repressor.  Plays important roles in the early stage of organogenesis of the CNS.  Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets.  Its transcriptional activity is repressed by MDFIC.  Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline.  Drives the expression of EPHB1 on ipsilaterally projecting growth cones.  Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'.  Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.
What are the official names of this protein?
Zinc finger protein ZIC 2, Zinc finger protein of the cerebellum 2.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes in the cytoplasm in presence of MDFIC overexpression. Both phosphorylated and unphosphorylated forms are localized in the nucleus.
Protein: HBA_MOUSE
Sequence: MVLSGEDKSNIKAAWGKIGGHGAEYGAEALERMFASFPTTKTYFPHFDVSHGSAQVKGHGKKVADALASAAGHLDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLASHHPADFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YFHC_BACSU
Sequence: MPQTEQIHQHSVLRDIIRSRRSIRKFKQEPVPSAVILDMLETAKYAPNHRVTEPWRFIYVSSETGKANLINTFAAFSKKSKPDMTEEKLQNFKNTLGRVPGFLLVVFQEDENERARDDDFAATSSLIQNLQLLAWEKGIGMVWKSGKILYDKEVHQAFGLQDNERFAAIIQTGYPDEAPEVKKRTPIRDRFTEM
What are the official names of this protein?
Putative NAD(P)H nitroreductase YfhC.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.