PharMolix/UniProtQA huggingface dataset:
Protein: IFNG_BUBBU
Sequence: MKYTSYFLALLLCVLLGFSGSYGQGQFFREIENLKEYFNASNPDVAKGGPLFSEILKNWKDESDKKIIQSQIVSFYFKLFENLKDNQIIQRSMDIIKQDMFQKFLNGSSEKLEDFKKLIQIPVDDLQTQRKAINELIKVMNDLSPKSNLRKRKRSQNLFRGRRAST
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLO2_PROM0
Sequence: MEFNKAQNIIGLRVLNDNVIWLWVKDKSVVVIDPSVHEPVIRYIDENNLHLKAILQTHHHSDHIGGTKPLIERWQNVKVIASSKEKKRIPFQNVSVEDGETLNILGEEVKIIEVLGHTSSHIAFFLNGENPVLFIGDTLFSGGCGRIFEGTYQQMYSSLERIKSLPKDTLIYCAHEYTKSNILWALNLKPKDQDLKNKLSEVEKKLSLNKLTIPFLLDEEMKINLFLRAKNLEEFTFLRANKDLWV
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: RL20_WIGBR
Sequence: MTRIKRGVSSKFRHKKILKKTKGYYGARSRSYRIAFQAFIKAGQYAYRDRKNKKRTFRKIWICRINSAVRKHGLSYSCFMYKIKKLSIFIDRKILSDLAVLNKEAFSELIKKVKSIS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: SHE9_ASPTN
Sequence: MHSLPLLLRQSLRSTGALSRSAHRPIRAPPLPSHLLRLPTAHPRPFSVCLQCQFRTQSASYPPNKESDKPLDTETPSKHPDSTASFLEESLKTQAEAGTPADSTTTTTTTTTSPPPQPTPNEPKTADSSLRDTLPSYLDNRRSQFSKQFTTMMDNLQSNIFVAGQRLNDLTGYSEIEALKKEIHTQEDRLRAARLHVRNAKEAYASAINRRSASQREVNELLQRKHAWSPVDLERFTHLYRNDHTNEVAENEAQEALTAAEREAEEAAAQLSKSILSRYHEEQVWSDKIRRMSTWGTWGLMGVNVLLFLVFQIAVEPWRRKRLVKGFEEKVIEAIEKEREMNHVEILSPTAAAATAGAVAPVEAAGEDAAPAPVEEETTSDGASVVEDTTGGVVEDRADLAHESYKAQLPSLPSTLSVDSWRQYLHDLFSERSMIITQRDLSSVALQSAAAGAAVMGLVIALIRPR
What is the function of this protein?
Required for the maintenance of the structure of the mitochondrial inner membrane.  Involved in mitochondrial morphology.  Causes growth arrest when highly overexpressed (By similarity).
What are the official names of this protein?
Sensitive to high expression protein 9 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SHE9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TBL3_MOUSE
Sequence: MAETAAGLCRFKANYAVERKIEPFYKGGKAQLDQTGHYLFCVCGTKVNILDVASGALLRSLEQEDQEDITSFDLSPDDEVLVTASRALLLAQWAWREGTVTRLWKAIHTAPVASMAFDATSTLLATGGCDGAVRVWDIVQHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRVWSLQDRSCLAVLTAHYSAVTSLSFSEGGHTMLSSGRDKICIVWDLQSYQTTRTVPVFESVEASVLLPEQPAPALGVKSSGLHFLTAGDQGILRVWEAASGQCVYTQPQMPGLRQELTHCTLARAADLLLTVTADHNLLLYEAHSLQLQKQFAGYSEEVLDVRFLGPSDSHIVVASNSPCLKVFELQTLACQILHGHTDIVLALDVFRKGWLFASCAKDQSIRIWKMNKAGQVACVAQGSGHTHSVGTICCSRLKESFLVTGSQDCTVKLWPLPEALLAKSTAADSGPVLLQAQTTRRCHDKDINSLAVSPNDKLLATGSQDRTAKLWALPQCQLLGVFTGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGSQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSQLDDHAITGGSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATVLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLRHEAPEELLAYDGVRGSLEALLPYTERHFQRLSRTLQAATFLDFLWHNMKLSPCPAAAPPAL
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Transducin beta-like protein 3.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: URE2_NATPD
Sequence: MSDPSEGSLTPGELLVDDAPVELNAGRETATVTVENTGDRPVQVGSHYHFFETNPALAFDRETAYGMRLNIPAGTAVRFEPGAERDVELVAIGGDRIVHGMDGLVNGDLDDEATRERAMDRAAAAGYRGVER
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_HELPJ
Sequence: MQDELFETEKAPQKNAKNAKNAPKKSFEEHVHSLERVIDRLNDPNLSLKDGMDLYKTAMQELFLAQKLLENAYSEYEKLQTPNKKA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A_ASHGO
Sequence: MGKEKTHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYHVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAYTLGVKQLIVAINKMDSVKWDESRYQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGAVKGKTLLEAIDAIEPPVRPTDKALRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPSGVTTEVKSVEMHHEQLEEGVPGDNVGFNVKNVSVKEIRRGNVCGDSKNDPPKAAESFNATVIVLNHPGQISAGYSPVLDCHTAHIACKFDELLEKNDRRTGKKLEDSPKFLKAGDAAMVKFVPSKPMCVEAFTDYPPLGRFAVRDMRQTVAVGVIKSVVKSDKAGKVTKAAQKAGKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBZ11_METRA
Sequence: MSTSSQTIDVDALLDFSACDGSYNSPSLSPSTASKPTFASPVTAAVSTPSLPSTTQTLSGPSHNYDMYRQQTGFVPGALTNTMAVNQTNNTGYQDFGSLDYLSSFSPENDVFDFNASPSQGTMEMEFESPADSQFFPTVNPSSIQHDTSALSQTSSVGRLWPGAHSQAALAKAQAQQRQQQQQQQLIQQTQRQTSPKSRGKAPQPTDPIVEQKITQLLNSMRAKPASNEPESQSVLNNLPKSKKDEEEMDEDERLLASEEGKKLSSKERRQLRNKVSARAFRSRRKEYISQLEAEIANKVNENGDLRSQNRALMDENKRLSDLTRMLLSSPSFSTFLDNLSANPTGLPQGSPVKIEQNPQQEQNQVPKDVNAYNSQFSSQQQIGMAMIPEQTMDFSLLSLGNTYNFQPQVFVVDTPEVPNAIDASVLSGKTSNFVEESFSSDDEKVEVPVIERPLKTKAIETPEAPVDEEFESDPEFALFHSEPATTTTTPKDIDTENLTGIDLFGGIESEKMFARYELVNATEEEATAAFAMARVQRISASIDSVVSRLELLTMDI
What is the function of this protein?
BZIP-type transcription factor that functions as either an activator or a suppressor, and which contributes to the regulation of fungal growth, conidiation, cell wall integrity, and virulence (PubMed:25673695).  Plays a key role in virulence against insects by mediating cell wall integrity, cell surface hydrophobicity, and adherence to hydrophobic surfaces (PubMed:25673695).  Exhibits negative regulation of subtilisin proteases, but positive control of an adhesin gene (PubMed:25673695).
What are the official names of this protein?
BZIP-type transcription factor MBZ1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGPA_ECOLI
Sequence: MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAAIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITLMALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIGHHWPLGILS
What is the function of this protein?
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
What are the official names of this protein?
Phosphatidylglycerophosphatase A, Phosphatidylglycerolphosphate phosphatase A, PGP phosphatase A.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THOC7_XENLA
Sequence: MGAVTDDEVIRKRLLIDGDGAGDDRRINLLVKSFVKWCNSGSQEEGYSQYQRMLSSLSQCEYSMGKTLLVHDMNLREMENYEKIYVDIESSIAAAHEKIAECKKQILQAKRIRKNRQEYDALAKVIEQHPDRHETLKQLEALDKELKQLSHTKENAEDKLELRRKQFHVLLSTIHELQQTLENDDKLAEESQESPMETQNP
What is the function of this protein?
Required for efficient export of polyadenylated RNA.  Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA.  TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.
What are the official names of this protein?
THO complex subunit 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the THOC7 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle.
Protein: VDAC2_ARATH
Sequence: MSKGPGLFTDIGKKAKDLLTRDYNSDQKFSISTYSASGVALTSTALKKGGVHAADVATQYKYKNALFDVKIDTDSSVLTTVTLTEILPSTKAIASFKVPDYNSAKLEVQYFHDHATVTAAAALKQNPLIDITATLGSPVISFGAEAGYDTTSKTFTKYNAGISVTKPDACLSIILGDKGDSLKASYLHHFDEFKRTAAVGEVYRKFSTNENTITVGGLYAIDHSTAVKAKLNNHGTLGALLQHEVLPRSLVTVSSEIDTKALEKHPRFGLSLALKP
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV.  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).  Involved in plant growth and development at the vegetative and reproductive stages.  Is important for leaf and pollen development and mitochondrial membrane potential steady state.  May be involved in ABA-mediated early seedling development and disease resistance.
What are the official names of this protein?
Mitochondrial outer membrane protein porin 2, Voltage-dependent anion-selective channel protein 2, AtVDAC2, VDAC-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.
Protein: CARB_HAEDU
Sequence: MPKRTDINTILIIGAGPIIIGQACEFDYSGAQAVKALREEGYKVILVNSNPATIMTDPDMADVTYIEPIQWQTLEKIIEKERPDAILPTMGGQTALNCALALSKNGVLKKYGVELIGATEDAIDKAEDRGRFKDAMTKIGLNTPKSFICHSFEEAWQAQEQVGFPTLIRPSFTMGGSGGGIAYNRDEFQAICERGFEASPTHELLIEQSVLGWKEYEMEVVRDKADNCIIVCSIENFDPMGVHTGDSITVAPAQTLTDKEYQIMRNASLAVLREIGVDTGGSNVQFAINPANGEMIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLNELRNDITGGLIPTSFEPTIDYVVTKVPRFAFEKFPQADDRLTTQMKSVGEVMAMGRTFQESLQKALRGLEIGICGFNLRSESPETIRRELANPGPNRILYVADAFGAGFSLEEVHHYSKIDPWFLIQIQDLVQEEMALEKRAFTELDYAELRRLKRKGFSDKRIAQLIKVSESDVRAKRYALNLHPVYKRVDTCAGEFKADTAYLYSTYEDECEAKPTTRQKVMILGGGPNRIGQGIEFDYCCVHAALALREAGFETIMVNCNPETVSTDFDTSDRLYFEPLTLEDVLEIIYKEQPWGVIVHYGGQTPLKLAHALEQNGVNIIGTSADSIDAAEDRARFQKILTDLGLKQPNNRTARNAEEAVKLAEEVGYPLVVRPSYVLGGRAMQIVYNVDELNNYMQEAVSVSNDSPILLDHFLKNAIEVDVDCICDSEQVLIGGIMQHVEQAGIHSGDSACSLPAYSLTNEVQGEIRRQTSAMAFALGVKGLMNVQFAVQNETIYVLEVNPRASRTVPFVSKATGNPLAKIAALVMAGKSLAEQNATTEIIPPYFSVKEAVFPFIKFPGVDTTLSPEMRSTGEVMGTGQSFAEAYYKAQLGAGERIPSTGKVFLSIADEDKPQIIRVAQYLQAEGYGLCATIGTAQYLRENGVGVQIINKVREGRPNIVDSIKNNEIAMIINTVNNLPESIKEAQEIRRNALKLHIPTYTTLAAAEAISEAVRHINKYDVNALQQLHLSSALANQITR
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: LEPA_CLOTE
Sequence: MTSERQKRVRNFSIIAHIDHGKSTLADRLLEETGTLTQREMDEQTLDTMDLEKERGITIKSQAARLIYKRDDEKEYILNLIDTPGHVDFNYEVSRSLAACEGAILVVDATQGIQAQTLANCYLALEHNLEIVPVINKIDLPSARPEEVKREIEDIIGIDASDAPLISAKTGLNIKDVLEAVVEKVPYPKGEEEEPLKALIFDSYYDAYKGVVCYVRVKEGTIKPGTEIKLMATGRKYEVTETGVFVPEYMKIDGLEAGDVGYITASIKNVRDARVGDTITEAKRPATEALEGYRPAIPMVFSGIYPVDGAKYGELKEALEKLQINDAALSFEPETSIALGFGFRCGFLGLLHMDIIQERIEREFNLDIITTAPSVIYKVTKTNKETIDVTNPTNLPEESEIAYMEEPIVECSIITPSDYVGPIMELCQNRRGVFKDMQYIETTRVVLNYDIPLNEIIYDFFDALKSRSRGYASLDYELKGYTQSKLVKLDILLNGDNVDALSMIVPEERAYSRGRQMAEKLKEIIPRQMFEVPIQAAVGSKVIARETVRALRKDVLAKCYGGDISRKKKLLEKQKEGKKRMRQIGSVEIPQEAFMSVLKTEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CMOB_PECAS
Sequence: MIDFGNFYQQIAKGPLSHWLNTLPSQLSSWQQESLHGKFKLWFNSLEHLPSLKPTSLDLNDSVTARIEPDISVGQREGIEKLLRNLMPWRKGPFSLYGVDINTEWRSDWKWQRVLPHISPLKNRLILDVGCGSGYHLWRMVGEGATMAVGIDPMQLFLCQFEAVRKLLGDDQRAHVLPLGIEQLPELAAFDTVFSMGVLYHRRSPLDHLWQLKNQLVAGGELVLETLVIEGDENQVLVPGERYAQMRNVYFIPSAVALTTWLEKCGFVDVRIVDICTTTTQEQRRTDWMITESLAEFLDPEDPTKTVEGYPAPVRAVLVARKPGAEL
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: SYA_DESOH
Sequence: MTGNEARKTFLDYFENQGHRVVRSSSLVPQADPTLLFVNAGMVQFKRVFMGEEKRDYTTATTSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKERAIELAWDLLLNGYKLPEDKLSVSVFHEDDEAFSIWKDRIGLAESRIARLGEKDNFWSMGDTGPCGPCSEIYMDRGEKYGCGRPDCAPGCDCDRFMEIWNMVFMQYNRQASGELTPLPHPSIDTGMGLERICAVIQDRDTNYETDLFIPIIRGIEAASGKTYGQAPDMDVCMKVIADHSRAAAFLIGDGVLPSNEGKGYVLRRILRRAIRYGRQLGLTRPFLSRTAGTVFEVMAEPYPELKENASFITNVLENEEVRFSETLDNGLRLLSETLDGMAAKGESVIPGGVIFKLYDTYGFPVDIVRDVVREKMIGLDMEGFDAAMAEQKAKSRSVVDFSKQPEAYRNLSAKGMKTGFVGYAGLAAQATVLALVNGGSELETATAGQEIEIVTDTTPFYGASGGQMGDVGVITADGLEITVTDTIKDPTGLVIHKGQVASGTVKKGQTISLAVDEDRRRATAANHTATHLLHAALGGIVGDHVKQAGSMVSPDRMRFDFTHFSMLDRATLDRIEVFVNDRIRENRAVTISEMSMDQAMEQGATALFEEKYGDTVRVVAVDGVSKELCGGTHAQRTGDIGLFKILSEASVASGVRRIEAVTGAGAVAFVQEQMGILAEAAGMLKESPAALAARIQKLLAESRTMAKEIAGLKTSLATASMEGPKSDDAKTLNGVKVIARTVTADNPAALRDLADRLKDKLGSGVVVLGAAADGKAFLIVSVSRDLTGRFKAGDIVREAAAVVGGKGGGRPDMAQAGGPQPEHLEAAIQKACDMIGKG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX41_YARLI
Sequence: MSDFEDNNPFAGADRRDSVSSDATDDGPSASFLATNTTNDFGGASFMAGGGSFYGAASQIGGLGGMGMSAYDPESALANPFDDGSNSFSATPTASITNQNDTAHEATNERTTTASQSNIPPIEIIEANKNHEGTSRGFITYTIRVGDVSVRRRYSEFESLRTTLTRMFPTLIVPPIPEKHSITDYAVAPTKAREDKDMIEHRQRMLQVFLNRCRNLPQISNCIVFQRFLDPHASWSEVLNSPPVSTLPRYSLRAPPVDPSNNVTEAHSYLPIPSANGVVRNRGGDEEGKQEAFFAEAEKTAKEYEAVIGGGLEKVARRILKRYTDIAGDYAELGGRFNALSLEESDSRMAATVEKVGQAIDSNYLATNHLVRELGRQFGEPLAESAQFSGVVRSVLKYRKQKALQLELTSDSLEAKRVTLASLESAEADSQRINDALGRTRSNNGPSTTNSGEQPSASPAPKKSSGFKIPGLSSLNSAFNNMMDADPEASRRQGIGKTREQIGQLEQALEVAQKDIVVANESVEKDLERFRAEREADLKCMIRAFLKCHIDWAKQNLDTWQSAQAEVESM
What is the function of this protein?
May be required for cytoplasm to vacuole transport (Cvt) and pexophagy.
What are the official names of this protein?
Sorting nexin-41.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures.
Protein: Y1599_THET8
Sequence: MNFQKLLKEAQKAQKKAAEVQERLERMTVVGSAQGLVEVEANGHGKILALRLKPEALKAFQDDPEGLEDLLLVAIQDAQTKAHELSEKEMAKELGGVGQMLGKLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein TTHA1599.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FABI_ARATH
Sequence: MAATAASSLQIATRRPSMSSPSKILKAGTYIVGANPGNASWDKLSCTRQLSNLGCLRNHSAVPTCKRPFSFSTRAMSESSENKAPSGLPIDLRGKRAFIAGIADDNGYGWAIAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVLPDGSLMEIKKVYALDAVFDNPEDVPEDVKTNKRYAGSSNWTVQEAAECVKKDFGSIDILVHSLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLRHFLPIMNPGGASISLTYIASERIIPGYGGGMSSAKAALESDTRVLAYEAGRKSNIRVNTISAGPLGSRAAKAIGFIDTMIEYSYNNGPIQKTLTADEVGNAAAFLASPLASAITGATIYVDNGLNAMGVALDSPVFKDLNSKN
What is the function of this protein?
Catalyzes the NAD-dependent reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Catalyzes the last reduction step in the de novo synthesis cycle of fatty acids.  Involved in the elongation cycle of fatty acids which are used in lipid metabolism.  Required for normal plant growth.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic, ENR, NADH-dependent enoyl-ACP reductase 1, Protein MOSAIC DEATH 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PTH_BRADU
Sequence: MRLFVGLGNPGAKYARNRHNIGFMAVDEIARRHGFSPWRRRFQGETSEGALGTERVILLKPTTYMNDSGRSVQEAAGFFKIAPGDVTVFHDELELPPGKVRVKVGGGIAGHNGLRSISAHIGNDYRRVRLGIGHPGVKELVHGHVLSDFAKADNDWVATLCDAVAEHAALIAKGTDATFANRVHLAMQAKGFLTKDDNGKE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_CHLCV
Sequence: MKTFKGVASAKDMRVAIVGACFNGPIADALVSGAQQTFLDLGGAEDMLTVVRVPGSFEIPCTLKKLLTSGVKYDAIVACGVLIKGETTHYDHIADQVSARISELSLEFNLPITFSVITAPCIDSAWQRAGIKGSNLGISGMKTALEMADLFKKL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ATPE1_THIDA
Sequence: MAMTMRLDVVSVEGSLFSGIVESVVAPAEMGAVGIYPGHAPLLTRLKPGAVRLRIPYQAEEEIVYVSGGMLEVQPYKVTLLADVAMREKALAEADLHAEKHRAEAVLKDRVTADAYARLEVELAKALTYVQGVQKLRRRGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain 1, ATP synthase F1 sector epsilon subunit 1, F-ATPase epsilon subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UPP_CORGL
Sequence: MDITIVNHPLVASRLTLLRDERSDNAAFRAAANDLGAMLIYEASRDLEVEHFDTKTPVAMAEGTRLKQPPIIVPIIRAGLGMIDPALSMIPDAQVGFIGLARDEETHEPVPYLEALPQDLSNQPVFLVDPMLATGGSLLHAIRLLADRGATDITAICMVSAQPGVDALAESGLPVRLVTATIDPGLDENAYIVPGLGDAGDRLYGPRNIDL
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: DEOB_SINMW
Sequence: MARAFLFVLDSFGIGNAPDAGAFGDLGADTLGHIAEFCAAGAADRAGLREGPLNLPNMSALGLMHAARLATGRLPAGMALPERVYGVYGAASEVSRGKDTPSGHWEIAGTPVTFDWGYFPADGDAFPPELVEAICREGDVPGILGNCHASGTDIIARLGEEHMRTGKPICYTSSDSVFQIAAHEQTFGLERLQDLCAVVRRLVDEYNIGRVIARPFVGSDPGSFTRTGNRRDYSVLPPAPTVLDRLKEAGRTVHAIGKIADIFAHQGVTRLTKANGNMALFDASLAAIDEAEDGALIFTNFVDFDMLYGHRRDVAGYAAALEAFDARLPDLDRRLKPGDMVILTADHGCDPTWRGTDHTRERVPVLMFGPTLRSRSVGIVGSFAHIGETVASHLGIDPGPHGRSLI
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.