PharMolix/UniProtQA huggingface dataset:
Protein: G3P2_BACSU
Sequence: MKVKVAINGFGRIGRMVFRKAMLDDQIQVVAINASYSAETLAHLIKYDTIHGRYDKEVVAGEDSLIVNGKKVLLLNSRDPKQLPWREYDIDIVVEATGKFNAKDKAMGHIEAGAKKVILTAPGKNEDVTIVMGVNEDQFDAERHVIISNASCTTNCLAPVVKVLDEEFGIESGLMTTVHAYTNDQKNIDNPHKDLRRARACGESIIPTTTGAAKALSLVLPHLKGKLHGLALRVPVPNVSLVDLVVDLKTDVTAEEVNEAFKRAAKTSMYGVLDYSDEPLVSTDYNTNPHSAVIDGLTTMVMEDRKVKVLAWYDNEWGYSCRVVDLIRHVAARMKHPSAV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NADP.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NADP to NADPH.  The reduced NADPH is then exchanged with the second NADP, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLC_BACAH
Sequence: MNPLIFKEDRPLDLIAVGRLCVDLNANETQRPMEETKTFTKYVGGSPANIAIGASRLGLQTGFIGKVSDDQMGRFITGYLKDNKINTDQIHIDCTGAVTGLAFTEIKSPEDCSILMYRDNVADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFLALEYAHKHDVVVFFDVDYRPYTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEQSNDQVTAERWFSHYAKIVVIKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLMQGLEIPQAMRLGGASASIVISKHSCSDAMPTRAEISAFMETAEELV
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: KTU_DROAN
Sequence: MSAGSRNKHSKFRNDDQLDISKEEFSRIKEALGNEEFRKLFFDYVDEIQDPANRKIYEEEITQLEKERGVEVRFIHPQPGFVVKTSLDGELKCFINIASSPEIEAPHNEVATNPENGNRGLSWYIPMAQTSSRDDADAKNNHCKVFDVVFHPDALHLAKRNSQFRKCLVDTALDAVEREYQVSLDRANLKFPKLDYKGIARPTVIRKLAENPTAEQLEPHPLQNIYPTAPPTSNPEPRVHPMKTKAAPVPEFTIPRYSIKHSHDVDLSEYTDELDAKLHVTVPRNLVVEIELPLLRSTAECQLDVTSKSVYLLSEKPGAKYRLKMDLPFTVDDKAGSARFDTDLRRLSITLPVVRSSVPQQRDMHDTLRHFSREDSGVELHSNSESPVEEEEADADLSDSKADTSETVTPTATPVHSAPTPFLKKSVHYQLPAKFDCNVLDNVMAFVLHVANVQPDSIEQLREQRSLHIQFATIGSGYYPTHYAFYVELPADEEGGSAIENVEAEAWDNNVVLKLCLSSQSKSPIRYMAGLDATDLNEYPVHGQYTVKPKRRDAQNKESAPLDVKFDHNKESLEVTIRPVPSATEEDEVEEQHEESHEEHQQHAQNKKPSKKQRKRNKKERSLSESACEDIVQEQHAENPAPPAKNFLKLPQRKQRSYSECNDSSVGSGASQRGILKRFSRYGPRPSMSDSCSSIDDYSSSYSCSVDASGASLFSQSFGGIPEEDRSDAGLSESCKKTVRFNDHITKQVFRLDSSILGQRKKNQKRRDLKLRAQQRRLSEGDSVDYEESRGDALKPQGKASNKGNKLHDSGLDLTGTAAGHGSHSDADAKNAMMFEMDEDDVM
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal homolog, PP1-interacting protein 20.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_HELAH
Sequence: MSAELIAVYKDEQIIDLESAKVLGLSDGVKALKGSEPIYFDDSPLALEVIRHSCAHLLAQSLKALYPDAKFFVGPVVEEGFYYDFKTASKISEEDLPKIEAKMKEFAKSKLAITKEVLTKEQALERFKGDELKHAVMSKISGDAFGVYQQGGFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGDEKNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLPKGARLRKRIEDLLSKALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYGIKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFCSFEQIQSEVSAILDFTHKIMKAFDFSYEMELSTRPAKSIGDDKVWEKATNALKEALKEHHINYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEHNNAEQPVMIHRAILGSFERFIAILSEHFWGNFPFFVAPTQIVLIPINEEHHVFALKLKEELKKRDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEMETEILSIRDREKQAQYKMPLKEFLNMVESKMQEVSF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGL3_ARATH
Sequence: MGRGKVELKRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEIALLIFSNRGKLYEFCSSPSGMARTVDKYRKHSYATMDPNQSAKDLQDKYQDYLKLKSRVEILQHSQRHLLGEELSEMDVNELEHLERQVDASLRQIRSTKARSMLDQLSDLKTKEEMLLETNRDLRRKLEDSDAALTQSFWGSSAAEQQQQHQQQQQGMSSYQSNPPIQEAGFFKPLQGNVALQMSSHYNHNPANATNSATTSQNVNGFFPGWMV
What is the function of this protein?
Probable transcription factor that binds specifically to the CArG box DNA sequence 5'-CC (A/T)6 GG-3' (PubMed:7632923, PubMed:25183521).  Plays an important role in the determination of flower meristem identity.  Involved in the specification of sepal identity.  Contributes to the development of petals, stamens and carpels (PubMed:15530395).
What are the official names of this protein?
Agamous-like MADS-box protein AGL3, Protein SEPALLATA 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS27A_METM6
Sequence: MAAKKGKKTSTKKSDYYKVEGNTVERLKKVCPKCGAGVFMAEHLNRFACGKCGYLEYKKNEKAESEE
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: ATG13_GIBZE
Sequence: MHQQPRGPARVSSPGATTQPNLPSRSNSTREAALGSRPRAGSNLVGRDVPNSPSLESPPIPAPPADSVRKLDQIIQNFYAKAAVLVLDSRIKSRPARGANGARKPNKWFQIETDEIDDFRDELKIWKNCGSLDNRPPPMVIEVYLDASRLKDSQSLVIVDENGKRWDVMEQLNSYGSSTDSSGASRRNNEVVIERWQVELKHSGMTSVDFGPILPTVYKKAIVFFRSLFITTRLLPAWKFASQGAAKNSHPALIPRCRIRLSQPDRPRYDQLRLPIDGRPDPVTEYVFGDLEVPVGRLSTLVTYRSDCNFRVDDSEALLSSRFMGVDENFFRPSLPQQHATSRAPAAEAGSLRDHRSKPNLNDIQQAYGSLSTFHGNVPIGTSPISALRSVRQPGSDTSSPPESIPAQHDVGGPSSLPVRQGTARPHLPALEGLGRRPSVSFQPFKAGSLSGSPVPRQLDAEPASPQSLTRPGIPSLRQAGNRTSLTAGMPASLRGGPPTSSGETAVAGSPRPASTSRYSSSFTHRRGRLSFGGASKAGDDEQGSSGRQSLASSVAQPGSGLLAEVAGTSSESLRDDNEQLEDFIKALDSKKTLQSFGPSKTGESATNKTVAQLSRFHMMRDSNNALTESMTSSVQMQRSSSSSSRQLTSVPGMTAPASVSASSSPGKPLSPHTPHTPAIPSRLSENSIIDYSGQGRITSRQGRTSDNTQPGTIRENTITQDGTTAIDIPLSPRLATYQRRASSVAIQNRSMADDDDTDSAFAHRSISLGADDREPPTLSILLGRQMQLEEDSTQRPSDRLEPAADTGSTETPDMLRQGLSEENPPEGLIPAATSSSPFGRRRYMGMASHKQTPPQSSRGSFNGSLNRQVRGDDDSVNEEPLVFDLSEMDPQGRRSIEEARSGASGGPNIGPDRGGYESRNASRRGW
What is the function of this protein?
Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy (By similarity).  Involved in ATG9 and ATG23 cycling through the pre-autophagosomal structure (By similarity).  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation (By similarity).  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy (By similarity).  Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: SHSA7_HUMAN
Sequence: MPALLLLVLLASSAGQARARPSNATSAEPAGPLPALLAHLRRLTGALTGGGGAASPGANGTRTGPAGGAGAAARAPPPAELCHGYYDVMGQYDATFNCSTGSYRFCCGTCHYRFCCEHRHMRLAQASCSNYDTPRWATTPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALAVGVGAKVAFSKASRAPRAHRDINVPRALVDILRHQAGPGTRPDRARSSSLTPGIGGPDSMPPRTPKNLYNTVKTPNLDWRALPPPSPSLHYSTLSCSRSFHNLSHLPPSYEAAVKSELNRYSSLKRLAEKDLDEAYLKRRPLELPRGTLPLHALRRPGTGGGYRMEAWGGPEELGLAPAPNPRRVMSQEHLLGDGGRSRYEFTLPRARLVSQEHLLLSSPEALRQSREHLLSPPRSPALPPDPTARASLAASHSNLLLGPGGPPTPLRGLPPPSSLHAHHHHALHGSPQPAWMSDAGGGGGTLARRPPFQRQGTLEQLQFIPGHHLPQHLRTASKNEVTV
What is the function of this protein?
Transmembrane protein that regulates gamma-aminobutyric acid type A receptor (GABA(A)R) trafficking, channel deactivation kinetics and pharmacology, necessary for fast inhibitory transmission in the brain.  Enhances the action of benzodiazepine, a primary GABA(A)Rs target drug, in the brain.  May affect channel kinetics of AMPA-type glutamate receptors (AMPAR), the brain's main excitatory neurotransmitter, necessary for synaptic hippocampal plasticity, and memory recall.  May regulate the induction and maintenance of long-term potentiation at Schaffer collaterals/CA3-CA1 excitatory synapses.
What are the official names of this protein?
Protein shisa-7, Cystine-knot AMPAR modulating protein of 59 kDa, CKAMP59, GABA(A) receptor auxiliary subunit Shisa7, Protein shisa-6-like.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Postsynaptic density membrane; Single-pass type I membrane protein. Note=Localizes at GABAergic inhibitory synapses and colocalizes with gephyrin in hippocampal neurons.
Protein: SOJ_HALH5
Sequence: MAKVISIANQKGGVGKTTTAVNLSACLAHLGQRVLLVDIDPQGNATSGVGIEKGDIDECIYDVLVEDVDTQDVIRTTNMENLDVLPSTIQLSGAEIELVSTISREVRLKRALDQVGRKYDFIFIDCPPSLGLLTINALTASDSVLIPVQCEYYALEGLSQLLNTVRLVQKHLNTDLAIEGVLLTMLDARTNLGIQVIDEVKKYFREKVFDTIIPRNVRLGEAPSHGEPIIRYDAKSRGAEVYLDLAKEVVANG
What is the function of this protein?
Inhibits the initiation of sporulation, Spo0J antagonizes this inhibition.  Soj ultimately inhibits the activation (phosphorylation) of Spo0A.  It is not required for chromosome partitioning (By similarity).
What are the official names of this protein?
Sporulation initiation inhibitor protein Soj.
What is the protein family that this protein belongs to?
Belongs to the ParA family.
Protein: MRAY_RHIME
Sequence: MLIWLVELADHFQFFNLFRYITFRTGAALFTSALIVFLFGPAMIASLRIRQGKGQPIRADGPQTHFKKAGTPTMGGLMILTGIVVSSLLWADLSSIYVVSTLLVTLGFGAIGFYDDYLKVTKQSEKGFSGKARLGIEFVIAAVAVFFMMQAALSAGAAGSTFGSSVTFPFFKDLMLNLGYFFVLFGGFVIVGAGNSVNLTDGLDGLAIVPVMIASAAFGLIAYLAGNAVFANYLQIHFVPGTGELAVILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVMIIIGGLFVIETLSVIIQVFWFKRTGHRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVILAMVGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G6PI_RUBXD
Sequence: MADVTFDYRNLLEVEGGLTGRELEEISPRLRAAVGTLLEDPPGFMRLPRTREHLEASLEVAERVRSDGATDFVHVGIGGSALGPMVLHRALSHPFYNLLPDRGGPRLHFAENADPATLSGILDVIEPEGTWVNVVTKSGSTAETMANFLVIRGALAEALGDFGYQARTVVTTDPEKGFLKRIADREDLVTLQVPPEVGGRFSVLSPVGLLPAAVAGLDVEALLAGAARCVEELEEQGAEHPAVVGAAMHHLMDASRGRNIRVMMVYADALERLAAWFVQLWAESLGKDGKGSTPHGAVGTTDQHSQLQLYMEGPQDKVIEIVEVREHPRDVGIPGAYEDLEGVGYLSGHTVGELLNVECDATRRALTGAGRPNATIRLGSLSAENLGYLMQALEVQTAVAGALYGVNPYDQPGVEAGKRITYARMGRPGYRA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_SALSV
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHCAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEERFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GATA_DESRM
Sequence: MDLFQLTAHQLHQLLTKKEISALDITEAVYNRIEQVEDKVKSYLTLTREQAEIKARQVDQKIAAGESIGPLAGIPIAIKDNMCTQGIRTTCASKILYNFVPPYSATSVEKVYTADMVMVGKTNMDEFAMGSSTENSGFHLTHNPWDLDRVPGGSSGGSAAAVAAGEAIISLGSDTGGSIRQPAALCGVVGMKPTYGSVSRYGLVAYASSLDQIGPFTRDVTDMAHVLNVICGHDPMDSTSANLKQTDYTQFLTNDIKGMKIGVPREYMADGIDPQVREKIKAAIQKLTELGAHVEETSMPHTDYAMPAYYLIATAEASSNLARYDGVRYGLRVEEARDLVDMFMRSRSQGFGDEVKRRIMLGTYSLSAGYYDAYYLKALKVRTLIKQDFDRAFEKYDALLSPTSPTTAFKIGEMVNDPIQMYLQDVCTIPVNLAGIPAISLPCGLANNLPVGLQLMGKAFDEGTLLRIAYTLEQNTEYTRLRPEI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: YDJP_BACSU
Sequence: MPYIILEDQTRLYYETHGSGTPILFIHGVLMSGQFFHKQFSVLSANYQCIRLDLRGHGESDKVLHGHTISQYARDIREFLNAMELDHVVLAGWSMGAFVVWDYLNQFGNDNIQAAVIIDQSASDYQWEGWEHGPFDFDGLKTAMHAIQTDPLPFYESFIQNMFAEPPAETETEWMLAEILKQPAAISSTILFNQTAADYRGTLQNINVPALLCFGEDKKFFSTAAGEHLRSNIPNATLVTFPKSSHCPFLEEPDAFNSTLLSFLDGVIGKS
What are the official names of this protein?
AB hydrolase superfamily protein YdjP.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: LPXK_HELPH
Sequence: MKSDKPFLERYFYDPTLLQKGLIFALYPFSLIYQGIATIKRKTAKKHDFKIPLISIGNLIAGGSGKTPFILEIAPRYQEVAIVSRGYQRDSKGLVVVSVKGNILVPQQTAGDEAYLLALNLKQASVIVSEKRELGVLKALELGAKIVFLDDGFRFNFNQFNALLKPKIPPYYPFCLPSGLYRESIKSYKEAHLVITEDKDYQRITSISHPTKRMLLVTAIANPSRLDAFLPKEVVKKLYFKDHALFDLKLLEKEFYQNSATSLLVTSKDLVKLQDCSLPLSVLDLKLEIDPKILEKIDRYILSYPCNTKERL
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: SYK_BUCCC
Sequence: MSKTLKIIQKKKSLEKELYTRKKKLKKLKKLGFNFPNTFHYIHTIKEIKKLYNNYTKKELEKINYKTKISGRIVNKRTFGKALFFVIRNNNHDIQIYIKSNYFPKNYYQKNILELDLGDIIGVKGKIFKTNTCELSILCKKIYLLTKSLRSLPDKYFGLKNQEIKYRKRYLDLISNNKIIKIFQKRSLIISNIRSFMKQKKFLEVETPMLHPIPGGANAKPFITYHNSLNEKMYLRIAPELYLKKLIIGGFNKIFEINRNFRNEGISTKHNPEFTMMEIYMSYSNYIDIMNLLEELCIFLVKKISKSLIIMYKSKKINFKKPIKKMTMIESILKFNKNIDISNFKNIKNIKKTATNLNIKIDSNASLGEITNLIFEKTTEKKIIQPTFITEYPIEISPLAKEKNKYFAERFEFFIAGYEIANGFSELNDPEEQKKRFKLQISKKNYTDKSKNFSYDKDYIIALEHGLPPTSGLGVGIDRLIMILTNQKTIKDIIFFPLLKKI
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRE28_ASHGO
Sequence: MSTKDTSGQSGYANDIRKLGEQTAHVSEQVLVQQERQRLGALEELHQSIIQIAEENSFVTPIKKDAANVHIDPRGIAVSVQQFKQLAEVLKVTHLEQETLDNFLRYTISDNDQLLDIKSVADSRYARLAEEVCQLEQEELRHLENEIISLNGNITEQTTKVIDANEKVKEECLEVSNGIERCWGLLNELETLRSTTDEGNVELGPLEETYQKWKSVDHFLQQKLHLKEQLRVLEDTRKSLSEVTKSSGNRAPDLDASEKFVTYRLLDSMWKKQFVDTTKIRDLELYPRTGKIQFQVADTIYVLAISGDQISNIQLFNDKLPAADLENNTQDLNKRFLGTSDVRRVVDFITHQQAVPQAQVH
What is the function of this protein?
Required for kinetochore binding by a discrete subset of kMAPs and motors.  Involved in kinetochore-microtubule binding and the spindle assembly checkpoint (By similarity).
What are the official names of this protein?
Spindle pole body component KRE28.
What is the protein family that this protein belongs to?
Belongs to the KRE28 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Chromosome, centromere, kinetochore. Note=Localizes to the nuclear side of the spindle pole body.
Protein: IMA_DROME
Sequence: MSKADSNSRQGSYKANSINTQDSRMRRHEVTIELRKSKKEDQMFKRRNINDEDLTSPLKELNGQSPVQLSVDEIVAAMNSEDQERQFLGMQSARKMLSRERNPPIDLMIGHGIVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLAEQAVWALGNIAGDGAAARDIVIHHNVIDGILPLINNETPLSFLRNIVWLMSNLCRNKNPSPPFDQVKRLLPVLSQLLLSQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLPRLGLLLQHNKSNIVKEAAWTVSNITAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQKEAAWAVTNTTTSGTPEQIVDLIEKYKILKPFIDLLDTKDPRTIKVVQTGLSNLFALAEKLGGTENLCLMVEEMGGLDKLETLQQHENEEVYKKAYAIIDTYFSNGDDEAEQELAPQEVNGALEFNATQPKAPEGGYTF
What is the function of this protein?
It is required for normal cell proliferation and may serve as an adapter molecule to form complexes with other proteins.  May act as a tumor suppressor in hematopoietic cells.  May play a role in the nuclear import of karyophilic proteins and some of these may be required for the normal transmission and function of proliferative signals in the cells.
What are the official names of this protein?
Importin subunit alpha, Karyopherin subunit alpha, Pendulin.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and nucleus in a cell cycle-dependent manner.
Protein: METE_BACCN
Sequence: MALHTSNLGYPRIGLQREWKKTLEAFWAQKIDEQQLITTMKEIHLEHLNVQKEKGIDFIPIGDFTYYDHVLDTAYMLGFIPSRFSNFTSYLDIYFAMARGSKDHVASEMTKWFNTNYHYIVPEYEEGLNISLKDNRPLRLYEEAKRELGIDGKPVILGPYTFLKLAKGYTQDQFPTILHKLIAPYVQLLTELHKAGARLIQIDEPIFVSLTKEEMIEAKKLYEAIQKEVPSANLILQTYFDSVEENYTELITFPVSGIGLDFVHGKEGNIKSIVEHGFPAEKTLAIGCIDGRNIWRANLDEVFALFETLKAHIEPKDWIIQPSCSLLHTPVDKTEETHLSPELFDALAFANQKLEELTLIKRGLSEGVNSIEIEITTYRNSHEAVRSSAARNRKDVQTARASLKEEDFSRPLPFEQRYDLQQKALQLPLLPTTTIGSFPQTPEVRQTRKQWRNGEITNEQYEHFIEQETEKWIRHQENIGLDVLVHGEFERTDMVEYFGERLAGFSFTKNGWVQSYGSRCVKPPIIFGDVAFISDMTVKETVYAQSLTNKVVKGMLTGPVTILNWSFVRNDLPRKEVCYQIALALRHEIERLESSGIRIIQVDEPALREGMPLKEKDWDSYIEWAVQSFRLATASVANETQIHTHMCYSNFEDIVDAIRALDADVISIETSRSHGEFIHTLEQTTYEKGIGLGVYDIHSPRVPSKEEMYTIVEQSLKVCNPKYFWINPDCGLKTRRTEEVLPALEHMVEAAKEARTLLKTNA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: ILVD_BRUC2
Sequence: MPPYRSRTTTHGRNMAGARGLWRATGMKDEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIESAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKVVWEDSVKKLDLVDAMVAAADDHYTDEQVKAIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHADRKRLFVEAGHLIVDLARRYYEQDDESVLPRSIATFSAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMADIDRLSRRVPVLCKVAPAVSSVHMEDVHHAGGIMGILGQLDNAGLLTTSIPTVHSETLAKALDHWDVTRTNSEMVHKFYSAAPGGVPTQVAFSQERRFDKVDTDREKGVIRSKEHAFSQDGGLAVLYGNLAEDGCIVKTAGVDDSILKFSGPARIFESQDSAVLGILNGKIKPGDIVLIRYEGPRGGPGMQEMLYPTSYLKSKGFGKACALITDGRFSGGSSGLSIGHVSPEAAEGGTIGLVREGDIIDIDIPNRKIHLAVDDATLAERRAEQDAAGWKPAEERKRKISTALKAYAAMATSAARGAVRKLPD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CDC10_YEAST
Sequence: MDPLSSVQPASYVGFDTITNQIEHRLLKKGFQFNIMVVGQSGLGKSTLINTLFASHLIDSATGDDISALPVTKTTEMKISTHTLVEDRVRLNINVIDTPGFGDFIDNSKAWEPIVKYIKEQHSQYLRKELTAQRERFITDTRVHAILYFLQPNGKELSRLDVEALKRLTEIANVIPVIGKSDTLTLDERTEFRELIQNEFEKYNFKIYPYDSEELTDEELELNRSVRSIIPFAVVGSENEIEINGETFRGRKTRWSAINVEDINQCDFVYLREFLIRTHLQDLIETTSYIHYEGFRARQLIALKENANSRSSAHMSSNAIQR
What is the function of this protein?
Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring approximate 15 minutes before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck.  This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck.  The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle.  Many proteins bind asymmetrically to the septin collar.  The septin assembly is regulated by protein kinases GIN4 and/or CLA4.  May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage.  Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation.
What are the official names of this protein?
Cell division control protein 10.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Bud neck. Note=Present at the bud neck during cell division. Probably interacts with phosphoinosides such as phosphatidylinositol 4-phosphate or phosphatidylinositol 5-phosphate.
Protein: CYTA1_DICDI
Sequence: MTLGGLKPEVHAANDEIRQVVAKVADELKSKLNTTEVEPVSYKTQLVAGTNYFIKVKTPAGFAHARVYKDLQQNHSVHSVKADGITEESEIVYF
What is the function of this protein?
Intracellular thiol proteinase inhibitor.  Inhibits papain, but not cathepsin B.
What are the official names of this protein?
Cystatin-A1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
Protein: ALLD_ECO57
Sequence: MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHVVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRQAAVEGIEIVDDIYQYLISDALYNTSYETKNPFAQ
What is the function of this protein?
AllD plays a pivotal role as a metabolic branch-point enzyme in nitrogen utilization via the assimilation of allantoin.  It is able to utilize allantoin as a sole source of nitrogen under anaerobic conditions.  Catalyzes the oxidation of ureidoglycolate to oxalurate.
What are the official names of this protein?
Ureidoglycolate dehydrogenase (NAD(+)).
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.