PharMolix/UniProtQA huggingface dataset:
Protein: RS7_PARXL
Sequence: MPRRREVPKREVLPDPKFGNVDVAKFMNVLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MGP1_DICDI
Sequence: MNVENQDPNIMVIPNNNLGPIDGNNISPAMNDENSNNGSSFLKNLVNTGTNLLFSSSSSIASPPNLGGLSNDSTNNNSNSNNTIDSSKPLSFENDMSDGYEALVRRSEIAIDQCKELLDFFKKRASEEEKYSKNISNMFSKFKVKDDHDTFQKGVSLLNKINDAESTIHRSFSQNITTNLYHPLNEAIKDMEKSRKRLLEDGKKLKNDLKDSIENVKKSNQKYEKLCREMEQAKLELIEEGNDTKSGKVETLEKKLEKTKLASIKAEDEYKEQINETNEFISGVYQNRLSENLREFQQFELTRLEIMKSNIRNYIGFMKDIPQALQCEIDSTKGFVDIIDPEVDLQNYIMNNSNPKKVLLPFIFEAYNDHKPFVDQHNQNSSSSSSTNALNYASPMSASGSITNTITSQSGSTIISNGASQPIEIPSPQPISEQQQIPPQQQQQQQQAQVPPTSINQSSSPPVNPMGRQQSLKENIFGFFNKATTNLKSSTSSLLTKDGNSTTSSNTSTSNSNQLSKSGIGLPIINTNSIFGVELEVLIENDNSKKKGNGVELEVPLILTQFVQALLKLESFKMDGVFVSLPSHFNIQQEKQKLDQTGTLENITDVYLIASLFKNWIGDLPNPLISYAIYQEIIEAPDNAWKIIESGIPILHRRVLHYIIDFLVDFVNCSKMDTHSISLIFTPVLIRSPFNGDSLLNSKKEVAVIENMIIDSLETKRGNYILKRNLPIIPDDENSDDDDDDSGHIDDENNSSTSGENDINTTNINNNNNVNSNNDTNNNNNNSNTTTTNNNNNNDSNNSNSTNNNNNNNNNNTNNDDNESNNSGYGVSSNGNNINSSVGGSVTHHFLYQTTPTNNVTPVLSDFFDTNSSNGSSKANTNTHNLGVRNSSNISFDTISTNQSDSEPVLVEYDNDDFDILSYK
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway (By similarity).  Regulator of the contractile vacuole network as well as involved in driving vacuole emptying.
What are the official names of this protein?
GTPase activating protein homolog 1, GTPase activating factor for raC protein BB, Rho GTPase-activating protein gacBB.
What are the subcellular locations of this protein?
Cytoplasm. Contractile vacuole. Note=Localized to tubules of the contractile network.
Protein: MATP_PHOPR
Sequence: MKYQQLENLEAGWKWTYLVKKWKEEEAITCHIDSSEAEAAIQSLLTIEHEPTKVIEWIDKHMSPALENKLKQAIRAKRKRHFNAEQVHTRKKSIDLDYRVWEKLAEKSQELGSTLSDTIEYLLSESNRTETVTKTVSDIRKDLSDLLD
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRF_CHLFF
Sequence: MTWLSGLYFISIASLVFCVIGLILSGVILISRKLLVKIHPCKLKINNDDSLTKTVDSGHSLLSSLLDSGIPIPSPCGGKATCKQCKVKIVKGADQPLETDRATFSKRQLEQGWRLSCQTKVQHDMNLEIEERYLNASSWEGTVVSNDNVATFIKELVVSVSPEHPIPFKPGGYLQISVPAYKTNTSDWKQTMAPEYHSDWERFNLFNQIIDNSLLESGSANKAYSLASYPAELPVIKFNIRIATPPFINNAPSPNIPWGVCSSYIFSLKPGDKITVSGPYGESFMKENNRPLIFLIGGAGSSFGRSHILDLLLDKHSTRDITLWYGARSLKENIYQEEYEKLEKDFPNFHYHLVLSEPLAEDIASGWDKNDPEKTNFLFRAFELGQLSKLSNPEDYLYYVCGPPLHNSSILKLLDNYGVERSSIILDDFGN
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BIOF_PSEMY
Sequence: MSFDLAARLAERQAADLFRQRPLLQTPQGPQVRADDQELLAFCSNDYLGLANHPEVIRALQLGAEKWGVGGGASHLVIGHSTPHHELEEALAEFTGRPRALLFSTGYMANLAVVTALLGQGDSVLQDRLNHASLLDAGLLCGARFSRYLHNDAVSLANRLRKASGNCLVVTDGVFSMDGDLADLPVLCAEARARDAWVMVDDAHGFGPLGATGGGIVEHFGLGLDEVQVLVGTLGKAFGTAGAFVAGSEELIETLIQFARPYIYTTSQPPAVACATLKSLELLRREGWRREHLQRLIARFRQGAAEIGLSLMDSPTPIQPILVGDSARALKLSALLKDRGLLVGAIRPPTVPAGSARLRVTLSAAHSEAQLELLLEALAECWPQVQADA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RNH2_NITMU
Sequence: MCSNEYPWVCGVDEAGRGPLAGPVFAACVILDPASPIDGLADSKTLTEGKRNSLTLAIKAYSIAWAIGFASVREIDRLNILQASLLAMKRAIGKLPVTPARVLVDGNHSPRLKFPVTTIVRGDSLVPEISAASILAKTARDAEMMALHRRFPRYGFDQHKGYSTEQHLAALKIHGVSIVHRRSFAPVRELMANEKDAES
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H1T_PIG
Sequence: AETAPAAPADSVPASVEKPPAKKRGKKPVGLTGTSRKAPSASVSKLITEALSVSQERAGMSLAALKKALAAAGYDVEKNNSRIKLGLKSLVGKGILVQTRGTGASGSFKLSKKAAPEPRKGKVKKPAAAKTKKLVLSRDSKSPKSAKANKRAKKSRTTAAQKAARSGRKTKEAKVKQQRKSPAKARAAKPKAGNPKLTQQKTNPRKATNRK
What is the function of this protein?
Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes.  Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination.  Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration.
What are the official names of this protein?
Histone H1t.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MYRIP_RAT
Sequence: MGRKLDLSGLTDDETEHVLQVVQRDFNLRKKEEDRLSEMKQRLAEENSKCSILSKHQKFVERCCMRCCSPFTFLVNARRRCGECKFSVCKSCCSYQKHEKLWVCCVCQQARLLRTQSLEWFYNNVKTRFKRFGSAKVLKNLYKKHRLESGACFDILGGGLYEPNLENEGSISGSDSTFYRQSEGHSMMDTLAVALQVAEEAIEEAISKAESQRDSLDKQNEASYLRDHRQELAEELAGTILQRIIRKQKDKADLHAEEEEPECTRPQSSGVKARGEGTAAPPGRHKARAALWRSQSAFSFTTEDTLKTSSAEAAPRQPKDRAQRLLEESALPSWRSMDGLDGKNLVPLLQSPDGNWMTLKDSSRQPPTRLLAKPKSRTFQALEVASSVASAYDELGSDSEEDFDYSEALSKLRPPSQGRLKQPQPQPAQAQSSGQGPLATSPSNPEAMCSDSETSSTSSSREAGCRAKLLWLQRKAPKNPSAEKTHLQGELDVNFNPQAAGGETSDSSDPEETLHTADRRARRWRRARVGPEESNRGLPSPSAYPPALHTAQVSDNVSETDISNEAQNSRSSTDSAEEKLRNRLYELAMKMSEKETSSGEDQESESKTEPKNQKGSLSSEENNQGVQEELKKKCSAVSLCNISTEVLKVINATEELIAESAGPWEIPPVSTDRDNGMFPLGTDQRSLDKQLTSLEENVYLAAGTVYGLEGQLSELEDAARCIHSSTGETELADLEDQVAAAAAQVHHAELQISDIESRISALTIAGLNIAPCVRLTRRRDQKQRSQVQTIDTSRQQRRKLPAPPVKAEKIEASSVTPIKTFNRNFLLQGSSTNRPTASTSNTKDLMEPVLESAVMY
What is the function of this protein?
Rab effector protein involved in melanosome transport.  Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A.  May link RAB27A-containing vesicles to actin filaments (By similarity).  Functions as a protein kinase A-anchoring protein (AKAP).  May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release.
What are the official names of this protein?
Rab effector MyRIP, Exophilin-8, Myosin-VIIa- and Rab-interacting protein, Synaptotagmin-like protein lacking C2 domains C, SlaC2-c, Slp homolog lacking C2 domains c.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle. Melanosome. Note=In presynaptic and postsynaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments.
Protein: VSR4_ARATH
Sequence: MKQLLCYLPWLLLLSLVVSPFNEARFVVEKNSLSVTSPESIKGTHDSAIGNFGIPQYGGSMAGTVVYPKENQKSCKEFSDFSISFKSQPGALPTFLLVDRGDCFFALKVWNAQKAGASAVLVADNVDEPLITMDTPEEDVSSAKYIENITIPSALVTKGFGEKLKKAISGGDMVNLNLDWREAVPHPDDRVEYELWTNSNDECGVKCDMLMEFVKDFKGAAQILEKGGFTQFRPHYITWYCPHAFTLSRQCKSQCINKGRYCAPDPEQDFSSGYDGKDVVVENLRQLCVYKVANETGKPWVWWDYVTDFQIRCPMKEKKYNKDCAESVIKSLGIDSRKIDKCMGDPDADLDNPVLKEEQDAQVGKGTRGDVTILPTLVVNNRQYRGKLEKSAVLKALCSGFEESTEPAICLSTDMETNECLDNNGGCWQDKSANITACKDTFRGKVCVCPIVDGVRFKGDGYSHCEPSGPGRCTINNGGCWHEERDGHAFSACVDKDSVKCECPPGFKGDGVKKCEDINECKEKKACQCPECSCKNTWGSYECSCSGDLLYMRDHDTCISKTGSQVKSAWAAVWLIMLSLGLAAAGAYLVYKYRLRQYMDSEIRAIMAQYMPLDSQPEVPNHTNDERA
What is the function of this protein?
Vacuolar-sorting receptor (VSR) involved in clathrin-coated vesicles sorting from Golgi apparatus to vacuoles.
What are the official names of this protein?
Vacuolar-sorting receptor 4, AtVSR4, BP80-like protein a, AtBP80a, Epidermal growth factor receptor-like protein 2b, AtELP2b.
What is the protein family that this protein belongs to?
Belongs to the VSR (BP-80) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein.
Protein: HBB2_NAJNA
Sequence: VHWSAEEKQLITSLWAKVDVPEVGAATLGKMMVMYPWTQRFFAHFGNLSGPSALCGNPQVRAHGKKVLTSFGEALKHLDNVKETFAKLSELHFDKLHVDPENFKLLGNVLIIVLAGHHGKEFTPSTHASFQKLVNVVAHALARRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-2, Beta-2-globin, Hemoglobin beta-2 chain, Hemoglobin beta-II chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YUF2_LEPBY
Sequence: IWDKRFKQINHFEQYLVENGIVVLKFFLNVSKEQQKKRFLARINEPEKNWKFSVSDAKERQHWDQYMEAFEDVFNNTSTSYAPWYIIPADHKWFTRLAVSDIIVSTLKSLHLSYPTVSEVRRAELLEAKKVLESEE
What are the official names of this protein?
Uncharacterized protein in chlN 3'region, URF2.
Protein: RAPA_SHESH
Sequence: MPFSLGQRWISDTESELGLGTVVALEGRMVTLMFPATDENRLFSRTDAPLTRVIFNPGDKAESHEGWSLTVSEVEEKDNLIIYHGIHSETGEQASLRETLLNHNIRFNKPQDRLFAGQIDRLERFGVRYQCQLLRHKLATSDLLGLQGPRVGLIPHQQWIAHEVGRRFAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERILVIVPDTLRHQWLVEMLRRFNLKFSVFDEDRCIEAYADNDNPFYTEQLVICSLELLRKKKRLEQALDADWDLMVVDEAHHLEWTEDAPSRAYRVVEALSEVVPGVLLLTATPDQLGHQSHFARLRLLDPDRFYDYEAFLKEESSYKDVASAADALASGNKLPDDAINSLTELLSEKDITPSINVIQATDIDPDQQQDARDELLQELLDRHGTGRVLYRNSRASVKGFPTRIFNAYPQAMPSQYVTAARVGAMMNGHLDTQGKVKQALSPEKIYQDFDSNSASWWKFDPRVDWLINFLKENRRKKVLIIASQAETALSLEEALRTREGIQTTVFHEGMSIIERDKAGAYFAQETGGAQALICSEIGSEGRNFQFASQLILFDLPLNPDLLEQRIGRLDRIGQNNDVEIHVPYLEKTAQECLMQWYHKGLNAFEQTCPSGHILFSEFAEPLLDVLINQNDDSLTELLNHTQTRYKELKTVMEQGRDKLLEINSHGGERANKLVQSLAARDEDTQLIGSVIRLWDVIGVEQEDCGENAIVLNPSEHMMFPTYPGLPEDGITVTFDREMALSRDDIALITQEHPIVQTGLDLITSSETGTTSVAVLKNKALPAGTIFLELIYMADASAPKSSQLYRYLPPTPVRILLDKNGNNLSDNVTYESFNKQLSAVNRHIASKLVNASQTILHPLFAKGEEFAEVELKLLADSARAKMTSQLTLELERLEALKAVNPNIRDEELEHIREQMNELNGYLDGCLLQLDAIRLVLVSHA
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: JHEB_TRINI
Sequence: LPSLSADAEAPSKIDTAYYNGTKTXXAPVYQYQFGVGXIEXLTYVFKGSQYQDIESPTAYQSK
What is the function of this protein?
JH esterase plays a crucial role in the decrease of JH activity in lepidopteran insects, by hydrolyzing the methyl ester of JH.  It is also involved in the transport of JH.
What are the official names of this protein?
Juvenile hormone esterase, isoform B, JH esterase, JHE-B.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
Protein: GLIJ_ASPFU
Sequence: MSPSPIEEQATRLLKEVPLIDGHNDFPYMIRGWFRNDINGQDAHLYDMPIGQTDLQRLQKGLLGGQFWSAFVPCPKNPDKEVGSLEALRQTLQQLDVIHRLIERHPTILQFADSAASIWSSFRAGRVASLIGIEGLHQIADSVSALRMLHRLGVRYVTLTHNCHNAFADAATVSPELHGGLSRKGERLIRELNRMGMMIDLSHTSHEAQTQALRLSRAPVIYSHSSIYSLRAHARNVTDENLHLLHRNRGVVMICFLRELLASEADQATLAHVIDHIIYAGTRIGYEHVGIGSDFDGMLRGPDGLHDVSCYPALVAGLLERGVSEEDVKRVMGLNVIRVLEEVERVAAELQGAGEECLCDELDEVWNEDIKEQLTRERERVRKLGPQK
What is the function of this protein?
Dipeptidase; part of the gene cluster that mediates the biosynthesis of gliotoxin, a member of the epipolythiodioxopiperazine (ETP) class of toxins characterized by a disulfide bridged cyclic dipeptide (PubMed:15979823, PubMed:21612254).  The first step in gliotoxin biosynthesis is the condensation of serine and phenylalanine to form the cyclo-L-phenylalanyl-L-serine diketopiperazine (DKP) by the NRPS gliP (PubMed:17154540, PubMed:21612254).  GliP is also able to produce the DKP cyclo-L-tryptophanyl-L-serine, suggesting that the substrate specificity of the first adenylation (A) domain in gliP is sufficiently relaxed to accommodate both L-Phe and L-Trp (PubMed:23434416).  The cytochrome P450 monooxygenase gliC has been shown to catalyze the subsequent hydroxylation of the alpha-carbon of L-Phe in cyclo-L-phenylalanyl-L-serine whereas the second cytochrome P450 enzyme, gliF, is presumably involved in the modification of the DKP side chain (PubMed:24039048, PubMed:23434416).  The glutathione S-transferase (GST) gliG then forms a bis-glutathionylated biosynthetic intermediate which is responsible for the sulfurization of gliotoxin (PubMed:21513890, PubMed:21749092).  This bis-glutathionylated intermediate is subsequently processed by the gamma-glutamyl cyclotransferase gliK to remove both gamma-glutamyl moieties (PubMed:22903976, PubMed:24039048).  Subsequent processing via gliI yields a biosynthetic intermediate, which is N-methylated via the N-methyltransferase gliN, before the gliotoxin oxidoreductase gliT-mediated disulfide bridge closure (PubMed:20548963, PubMed:22936680, PubMed:24039048, PubMed:25062268).  GliN-mediated amide methylation confers stability to ETP, damping the spontaneous formation of tri- and tetrasulfides (PubMed:25062268).  Intracellular dithiol gliotoxin oxidized by gliT is subsequently effluxed by gliA (PubMed:26150413).  Gliotoxin contributes to pathogenesis during invasive aspergillosis (PubMed:17601876, PubMed:18199036).  In macrophages and neutrophils, gliotoxin showed inhibition of various different cell functions including cytokine production, antigen presentation, phagocytosis, and production of reactive oxygen species (PubMed:17601876).
What are the official names of this protein?
Dipeptidase gliJ, Gliotoxin biosynthesis protein J.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Protein: PPE37_MYCTU
Sequence: MTFPMWFAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSWQGPSADRFVVAHQPFRYWLTHAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALVTTNFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTSAASSAASSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVFTFLAYLVLDPLIYFGPFAPLTSPVLLPAGLTGLAGLGAVSGPAGPMVERVHSDGPSRQSWPAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTPGSSAAQGLYAVGGPDGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLADDGRLTMPNTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPHTWDGSD
What are the official names of this protein?
Uncharacterized PPE family protein PPE37.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: RS4_BURCJ
Sequence: MARYIGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRTSGARTSDYGTQLREKQKVKRIYGVLERQFRRYFAEADRRKGNTGENLLQLLESRLDNVVYRMGFGSTRAEARQLVSHKSITVNGVVANVPSQQVKAGDVVAIREKAKKQARIVEALSLAEQGGMPSWVAVDAKKFEGTFKQMPERAEIAGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: NU1C_MESVI
Sequence: MLLTINLKDSFLTFFSNLGFSNEFSKALWIPLPILLLIILAVVGVLVVVWLERKISAAVQQRIGPEYAGPLGVLQPLADGLKLAFKEDIIPSKGDVLLFTLGPAIVVIPIFLSYLIVPFGENLIVSNINLGIFFWITVSSVAPLGLLMSGYGSNNKYSFLGGLRATAQSLSYEIPLALCVLSICLLSDSLSTIDIVQKQSTYGILGWNIWRQPIGFIAFIIAALAECERLPFDLPEAEEELVAGYQTEYTGMKFGLFYIGSYVNLLVSALFASVLYLGGWSLPIPIEFLLNKMSLNASDSEVQVISAFLGIGMTLLKTYLFLFLSILTRWTMPRVRIDQLLDLGWKFLLPISLGNLLLTASLKIALL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LSHB_EQUAS
Sequence: MEMLQGLLLWMLLSVGGVWASRGPLRPLCRPINATLAAEKEACPICITFTTSICAGYCRSMVRVMPAALPPIPQPVCTYRELRFGSIRLPGCPPGVDPMVSFPVALSCHCGPCRLKTTDCGGPRDHPLACAPQTSSSCKDPPSQPLTSTSTPTPGASRRSSHPLPINTS
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin/choriogonadotropin subunit beta, LSH-B/CG-B, Luteinizing hormone subunit beta, Lutropin/choriogonadotropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRE16_PHYIT
Sequence: MSKLFYAFAVLAVHVLTSSPTTAASNLPVNLVTGPAFTTPAGAAHRRFLRSIHEGEDSLKPSAFSEERTALRAMAYLLKPKQKKLAAALKKSTSKHKLSVAPEKMKSIQVLGDPKNPEREWFKRLYNSKRGDPQTLRKLGQFKTEAQLSRYIKFYDDMLAKAKNVRVQTK
What is the function of this protein?
Effector that is involved in host plant infection.  Contributes to virulence during the early infection stage, by inhibiting plant defense responses induced by both PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI).
What are the official names of this protein?
RxLR effector protein CRE16, Core RXLR effector 16.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: GWT1_ASPOR
Sequence: MDSSYKARKEAFVSNLAGGSILEINAVTLVAPTSVLLWSVLQSRLSFFIPYGALALVTDFFLNVLPILFATTLYSSAPWTLNILLALPALILLFTSTPSRTQQKAKPPRPSAAAKKNTPKHASDSPEPLPVHPFLTTYRAAMMVITCVAILAVDFRIFPRRFAKAENWGTSLMDLGVGSFVFSSGVVSARSILKGRNSHSKKAGLWQRLAASARHSIPLLVLGLVRLYSVKGLDYAEHVTEYGVHWNFFFTLGLLPPFVEIFDALAAIIPSYEILSLGIVVLYQVALESTDLKSYILVSPRGPDLLSKNREGVFSFLGYLAIFLTGRAIGIRIIPRGTSASRSPQQARKSVLISLGLQTLVWTTLFVFNSTHAMGLGAGIPVSRRLANMPYVLWVSAFNNAQLFLFCLLESTFFPSIHRETGKDGELERTSFATSRIMTAFNKNGLALFLVANLLTGAVNLSVPTLDVTTAHAMVVLIAYVAMITGVALALDRANIKLSL
What is the function of this protein?
Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
What are the official names of this protein?
GPI-anchored wall transfer protein 1.
What is the protein family that this protein belongs to?
Belongs to the PIGW family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IGF1_HORSE
Sequence: MGKISSLPTQLFKCCFCDFLKVKMHIMSSSHLFYLALCLLTFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVR
What is the function of this protein?
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.  May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts.  Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.  May play a role in synapse maturation.  Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.  Acts as a ligand for IGF1R.  Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways.  Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4.  Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.  Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (By similarity).
What are the official names of this protein?
Insulin-like growth factor I, IGF-I, Somatomedin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXT_THEP3
Sequence: MRVGVLAIQGSVREHIEKLKLIDGVEAVLAKDKNTLLSLDALIIPGGESTAIGKMIVDFGLKDAILKLNERKIPIWGTCAGMILMAKYIVNDDKVHLGIMDISVKRNAYGSQLDSFKTKLIIPAVSNNEIEAVFIRAPYIENVGNGVRILAKHQGKIVAAQQDNLLATSFHPELTDDLSFYKYFLRLNS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: IPI1_ASPCL
Sequence: MGSSAKKKKEKKKDFQKTKLRVGKTKAKPENFTDTSFKAKSIVLNQQSLHISAPSADAQFTHHLSLTSSKSDTQRRDSLAHLTTSIVSRPVDSPLPQPVSAILPTLLPLILDASNGVRTQLLKLLRALPPADVQDHVAQLLPYIRAGMTHLAADLRVSAVEVLAWLVDVAGAEVVACAGGWIKTLNCFLSVLGWHTEESSKWSSSSSASVSASASATRASFGKAGAQGKPMIKMLGALAEFLQVGIGRPAEAAIGLDASDAEAGVAGWEFPLRHAAQHMVPRSSAPYIHLNLFGQPRDEEGEMYETREDRYRVFASRFLGAVQRGLEGARGEGGEVGRASAGVSKVLKEAIAYGPGP
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein ipi1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.