PharMolix/UniProtQA huggingface dataset:
Protein: YVDS_BACSU
Sequence: MNWVLVFIAGLLEVVWASSLKHADSLLDWIIIFILIAVSFILLIRSYQKIPMAAAYTVFVGIGTVGTYLTGIVLGESFSAAQMFFLALLLAGILGMKLFTKESKSQPGGEK
What are the official names of this protein?
Uncharacterized membrane protein YvdS.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMP_CLONN
Sequence: MKNNLINMDEINKLIKPIVEELNYELYYIEYVREQNENYLRIYIDSSKGINLEDCEKVSRKVSDILDEKDPISDSYYLEVSSPGIERVLYTEEHLHKYTNNQIIVKLAKLFEGSREHQGNLISFNDDTVTIEKENESINIPRERIKKIILKGEF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRX2_RICFE
Sequence: MTENKNFEFIENEIKNNKVVLFMKGTKEATMCGFSAKVVAILNKLGVEFRDINVFVNPEFREDLKKFSDWPTFPQLYIKGELVGGCDIATELYNNGELEKMLKG
What are the official names of this protein?
Probable monothiol glutaredoxin 2.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. Monothiol subfamily.
Protein: Y020_SIFVH
Sequence: MVEVVKKQIECKIKINSVNGIVSLDCETKVIFNVKDSEMPYAVSSIKEIGFVETIKTDQVKNMINRIVEELDKRIDEIKEGLNELEKSGLTIEVD
What are the official names of this protein?
Uncharacterized protein 20.
Protein: PSD_PECAS
Sequence: MLDNIKIKLQYWLPKIWLTRLAGWGANKRAGKLTKLVIDLFVRQYHVNMQEALQPDTASYRTFNEFFVRPLRPGIRPVDPHAHRLVQPADGVLSQFGPITDGKLIQAKNHDYTLEALLAGNYMMADLFRDGLFATIYLSPRDYHRLHMPCDGVLREMIYVPGDLFSVNLLTADNVPNLFARNERVICLFDTEFGPLAQILVGATIVGSIETVWAGVVTPPREGIIKRWTYPQAGEEGAVVLAKGEEMGRFKLGSTVINLFTAGDLQFAAHLNIMSVTRMGEPFAEVRQDEQTPVVFPEGTELEENDAAQPPVAATSEPVQADGQNPAAEVSGQTGHKPDAP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CAPON_DROME
Sequence: MPSTPYDLVQDDQDLRVPLHAEQAFFHGITFQAKFVGWEEVPRPNTRAEIVQAMRRIRYECKVQNLKKRKVTIHISVNGVRVVLKKRRRKKKNWTNDPEDIELLNHPIYRIFYVSHDSSDLKIFSYIARDASTDTFKCSVFKSHKKSQAMRIVRTVGQAFEVCHKFNLHKNSLEPNDERSDISSSELLDVEQISEQQLSEDGERGGGDNETPKKEHLAITPDLNHTQPQRPNHLDIMPSHSSLRKSNSLLCDVDDKSPGSPSSPRSEITQLKDQLEAQALQTRQALGQLMLVREQLISETNARIEAQARTQQLLQQNRELLEHLASLGAYNEQQTAGLTSANIGMAPQQSQLQMLLQATSNNNNLATINQQISNLGSINQQLTSLSHQLSGLNQQSQHLQNLQQQQQQQQQQQQQQTQAAPTAATPPPAAGGSSPYPSMSALQSISNQLQQQQQQQQQDALSKDLFQVNQELLNRLQALNLNANPGQSQPTPSATAHNSFFYVNPLSCTPATPNNNAGGAGGFNFLTSPAATGTLTPSPLGTMNRNSFAGSSSLNEDIRLSIEQNLNNLEEQLKAAVSNGNLAGLACGGSTSTRDTSRSSSTLDSPSSPRLRSSNNNISPGSSNGNQNHNNNSNSNSSSSRETRFNTVLLRVTDEAGHQRKLSATPSFITRSTSEKVPNRSQMMSQVQRTTWARHTTK
What is the function of this protein?
Putative adapter protein.
What are the official names of this protein?
Capon-like protein.
Protein: PYRF_CLOAB
Sequence: MIIDRLFDSVEKKGHVCLGLDTDITYVPEEFCKKFNSIEDAIFNFNKKIIDATLDVVSCYKVQIAYYEAYGLKGLLAYKRTLEYLREKKAIAIADIKRGDIAKTAEMYAKAHFEGDFEADFVTLNPYMGLDGIEPYMPYIEKMEKGLFILLRTSNKGAYDIQYIKTQGGKNVYDEVGEKIYDLGQKATGRSKYSSIGAVVGCTHVEEGVEIRNKFKNMFFLIPGYGAQGGTAKEVSLYLREGNGGVVNSSRGILLAYKKEENGEKIFDECARLAAINMRDEIRKTL
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: RL28_TRIEI
Sequence: MSRKCQLTGKKANNGYSVSHSHIRTHKLQHANLQWKKVWWPQGKKWVKLKLSTKAIKTLQSKGIQAMAKQAGIDLNKF
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RPIA_YEAS7
Sequence: MAAGVPKIDALESLGNPLEDAKRAAAYRAVDENLKFDDHKIIGIGSGSTVVYVAERIGQYLHDPKFYEVASKFICIPTGFQSRNLILDNKLQLGSIEQYPRIDIAFDGADEVDENLQLIKGGGACLFQEKLVSTSAKTFIVVADSRKKSPKHLGKNWRQGVPIEIVPSSYVRVKNDLLEQLHAEKVDIRQGGSAKAGPVVTDNNNFIIDADFGEISDPRKLHREIKLLVGVVETGLFIDNASKAYFGNSDGSVEVTEK
What are the official names of this protein?
Ribose-5-phosphate isomerase, D-ribose-5-phosphate ketol-isomerase, Phosphoriboisomerase.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_XANOP
Sequence: MTRAFNFSAGPATLPESVLRQAQAEMVEWNGVGASIVEISHRSADFMAVAAAAEADLRSLLSIPDDYAVMFTAGGATTIQALLPLNFAAPGQAADYVITGHWGKTAIKQASPYVDARIAADAETGGFIDIPPAASWTLSPHSAYVHITANETIHGVEFRDTPEVGTLPLFADFSSSIASEPLDISRYGLIYAGAQKNLGPVGISVVIVRRDLLERAGQPRADIFNYASHVARDSMLNTPPTWNWYLLGLTVKWMLEQGGVQEFARRNAEKAALVYGAIDGAGGFYRNLITPAVRSRMNIPFFLPDEQLDALFVSESKAAGLLALKGHKAVGGIRASLYNAMPLAGAQALANFMHDFQQRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_THIDA
Sequence: MKEPFTNASYFPPVETALVDPNGLLAIGGDLSQERLLDAYRHGIFPWFNPREPIQWWSPDPRMVLPPAEIRVTRSLAKRLRNAGFELRVDSAFIEVMRACGAPREGAWGTWISAPMIAAYGRLFDAGYAHSIETWRDGRLVGGLYGVAIGRMFYGESMFSREPDASKVALVRLARQLERWGFGLIDCQMETPHLASMGARPIPRADFTARLAELVNLPHLPGPWTFDS
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSF3_BOVIN
Sequence: MPLPYVGMALRRLAWAVASCRLAPWTRGASGPLHSAPAARSDCSAPVFIRAPAFGDRLALIDQHGRHTYKDLYLRSLRLSREICQLRACADGDLREERVSLLCSNDVSFVVAQWAAWMSGGVAVPLYRKHPRAQLEYFIQDSRSSVVLAGPEHVELLSPVAQKLGVPLLPLPPTVYHGVAEDPEEGLVLERNWRDRGAMIIYTSGTTGRPKGVLSTHDNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNKLLCPLWVGATCVMLPEFSAQLVWEKFLSSEAPQINVFMAVPTIYSKLMDYYDKHFTQPHVQDFVRAVCEEKIRLMVSGSAALPLPVLEKWKGITGHTLLERYGMTEIGMALSNPLTAARLPGSVGTPLPGVEVRIVSENPQKDSSPYLIHAEGSEENTKVTPGFEEKEGELLVRGPSVFREYWDKPEETKAAFTSDGWFKTGDTVVFKDGCYWIRGRTSVDIIKSGGYKVSALEVERLLLAHPSITDVAVIGVPDMTWGQRVTAVVTLQEGHSLSHRELKEWARGVLAPYAVPSELLLVEEIPRNQMGKVNKRDLVRQLYPHEKGAPEAGSQ
What is the function of this protein?
Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester.  May have some preference toward very-long-chain substrates.
What are the official names of this protein?
Malonate--CoA ligase ACSF3, mitochondrial, Acyl-CoA synthetase family member 3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VM3JA_BOTJA
Sequence: ATRPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSKDYSEIHYSPDGREITTYPPVEDHCYYHGRIENDADSTASISACNGLKGYFKLQRETYFIEPLKLPDSEAHAVFKYENVEKEDEAPKMCGVTQNWKSYEPIKKASQLAFTAEQQRYDPYKYIEFFVVVDQGTVTKNNGDLDKIKARMYELANIVNEIFRYLYMHVALVGLEIWSNGDKITVKPDVDYTLNSFAEWRKTDLLTRKKHDNAQLLTAIDFNGPTIGYAYIGSMCHPKRSVGIVQDYSPINLVVAVIMAHEMGHNLGIHHDTGSCSCGDYPCIMGPTISNEPSKFFSNCSYIQCWDFIMNHNPECIINEPLGTDIISPPVCGNELLEVGEECDCGTPENCQNECCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYALFGADVYEAEDSCFKDNQKGNYYGYCRKENGKKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNDDEHKGMVLPGTKCADGKVCSNGHCVDVATAY
What is the function of this protein?
The dimeric form jaracetin may be a dimeric form of jararhagin-C.  It binds to von Willebrand factor (VWF) and induces its interaction with GPIbalpha (GP1BA) (via the vWF A1 domain), resulting in platelet aggregation.  Also binds the alpha-2 subunit of the alpha-2/beta-1 (ITGA2/ITGB1) integrin.  It potently induces platelet aggregation in citrated platelet-rich plasma.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like jararhagin, HF2-proteinase, JG, Jararafibrase I, JF I, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_BEII9
Sequence: MGQKVNPIGLRLGINRTWDSRWFANKGEYSKLLHEDMRIREVLMKNLKQAAVSKIIIERPHKKCRVTIHSARPGVVIGKKGADIDKIRKLVSKLTDSEVVINIVEVRKPEIDATLVADSIAQQLERRVAFRRAMKRAVQSAIRLGAEGIRINCSGRLGGAEIARLEWYREGRVPLHTLRADVDYGVATAHTAYGTCGIKVWIFKGEILEHDPMAQDRKMAELDHAGGGGGGERRRRERDAA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: FIE2_ORYSJ
Sequence: MAKLGPGQGLGCEAAVGLLAPSRKREYKACNKLTEGKRPLYAIGFNFLDFHYYEVFATVGGNRVTTYSCLKDGNFAILQAYIDEDKDESFYTLSWACDLDGTPLLVAAGSNGIIRVINCATEKLLKTFVGHGDSINEIRTQALKPSLIISASKDESVRLWNVHTGICILIFAGAGGHRNEVLSVDFHPSDIYRIASCGMDNTVKIWSMKEFWPYVEQSFTWTDLPSKFPTKYVQFPVLVAVVHSNYVDCTRWLGDFILSKSVDNEIVLWEPKTKEQSPGEGSIDILQKYPVPECDIWFIKFSCDFHFNQLAIGNREGKVFVWEVQSSPPVLTARLTNPQCKSAIRQTAVSFDGSTILACSEDGSIWRWDEVDHPKA
What is the function of this protein?
Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  They act via the methylation of histones, rendering chromatin heritably changed in its expressibility (PubMed:23505380, PubMed:24020752).  Involved in the regulation of seed endosperm development, grain filling and seed dormancy.  FIE2-containing PcG complex in seed endosperm regulates the expression of various transcription factors by trimethylation on histone H3 'Lys-27' (H3K27me3) of target genes.  Involved in the overall expression regulation of a large number of nutrient metabolism genes (PubMed:23505380).  Involved in the regulation of seed endosperm development.  Involved in the regulation of vegetative development, particulary in stem cell maintenance in the root system, where it maintains the suppression of key differentiation regulators (PubMed:24020752).
What are the official names of this protein?
Polycomb group protein FIE1, Protein FERTILIZATION-INDEPENDENT ENDOSPERM 2, OsFIE2, WD40 repeat-containing protein 153, OsWD40-153.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ESC family.
Protein: PURT_BIFAA
Sequence: MLFLGSGELGKEVTIELMRLGAWVCAADSYAGAPAQQVAHEYRVLDMANADQLRALFDEIQPDIIVPEVEAIATSELAAAAARGAQVVPSAEIAAICMDRERLRVLAHEELGLPTTPYRFAGSLEELREGAQIVGYPCVVKPIMSSSGHGQSVVRSADAIDAAWTEAQEGRRAHDEGDVSRVIVEALAPLDYELTVLTVSSSAGIVTCAPIGQRQESGDYRESWQPATFTPDVLEQAQHIARTAVEGLVAKAQASGEKGWGVFGVELFVLTDGNVLFNEVSPRPHDTGMVTMASQRLSEFALHARAILGLPITQEHVALSIPEGTVAASHAIVVQGDGEAEFRNVAAALAEPGTDLRVFAKPEVHGHRRMAVALAVGGDEADARAKAGNVAESLDIAIV
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: YLBG_SHIDS
Sequence: MLHTANPVIKHKAGLLNLAEELSNVSKACKIMGVSRDTFYRYRELVAEGGVDAQINRSRRAPNLKNRTDEATEQAVVDYAVAFPTHGQHRASNELRKQGVFISDSGVRSVWLLHNLENLKRRY
What are the official names of this protein?
Uncharacterized protein YlbG.
Protein: TILS_XYLFT
Sequence: MTVSSPFPRIPDPGVPVLVAFSGGLDSTVLLHCLASQPTQRIHGLEAIHIHHGLNENADAWTAHCAAFCTQHDIRLHIARVHVSHNSGQGLEAAARTARRAAFAHTLQHGHYLALAHHCDDQAETWLLRALRGSCDGLAAMRPLTPFAAGHLWRPLLTHSRAQLLDYAQQQHLDWIEDSSNADLRHDRNFLRIHVLPLLHQRWPQATAVLARNAALAAANADLLNAEDAVLLPDLLDPDGALDINALTAHPPARRARLLRAWCARAGAPPLPERGVNIIERELLPARHDSAACFTWSHTEIRRWRLRLYLHRPQPPWPPDWQPLWSGTAPLILPDGGQLHLESTDHETVPGFPHPLRVRARRGGERLILPGRTHSHPLKHLLQDVGIPPWRRASMPLLCDGEQILAVGDALLAAPLVTWLQAHRLKLRWQYHNNTCI
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEPA_YERPE
Sequence: MIATLLSSLLLTGPISAGAETQGLLPAQDLLPDIGTSAGATLSIDQEMAMGDFYVRQMRASAPLIYDPLLTQYINTLGNRLVANANSVRTPFHFYLVNNDQINAFAFFGGNVVLHSALFRYTDNESELASVLAHEISHVTQRHLARAMEEQQRLAPLTWVGVLGSILLTMASPQAGMAGLSGTLAGAQQGIISFTQGNEQEADRIGIQVLQRSGFDPQAMPNFLQKLADQSRYVSKPPEMLLTHPLPDSRLSDARNRANQMKPHPTASSQDYLFAKMRILGMYGADENSLTPELLDKLSKGTVREQLAAKYGQAVQLYQAKKYDEARNLLQPLLAQQPGNIWFLDLMTDIDLGQNKSAAAIARLQNAMVKQNDEPVLQLNLANAYVQGRQPAAAIKLLHRYTFAYPNDPNGWDLLAQATATQGLRDQELAARAESLALSGKLTQAIGLLSDASARVKLGSLEQARYDARIDQLRRLNERFRKYQKS
What is the function of this protein?
Functions as both a chaperone and a metalloprotease.  Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
What are the official names of this protein?
Beta-barrel assembly-enhancing protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48 family. BepA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PF20_CHLRE
Sequence: MAAAGLDTLRLEDSDDDFKYEEVDVMSDGEDDASEDLDAALRKLQQFTSKQEAATGPARTTEVKPGQVVKKPEVIDDFLRNFFIKMGLSRTCECFEAEWYELKATGRLDNSTTVPDVYLRNAELEDDVAGLRRELAEAKSIAGRASATWDKFRKERDFHRMHHKRVAQEKNKLLTDLRRLKEHYAKYEPTILELKKKYETLMKEKMMMSLERDKLAARVDALEQVASSPLPGAERSLGGQSTAAAGGGASGRALGATNRALTGDVPPAAGAAAAAATGRSGAVSAGPRSGWASLNAPPRRNPYADLEFPAAPVKMLSLNKTFKGHLLSVANLALHPTKPILVTASDDKTWKMWHMPGGDLIMCGEGHKDWVAGVDFHPAGTCLASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAGKCRMALRGHVDSVNDLAWQPFSSSLATASSDKTVSVWDARAGLCTQTYYGHQNSCNGVSFNILGTQLASTDADGVVKLWDTRMTAEVATINTGKHPANKSCFDRSGQVLAVACDDGKVKAYSTTDGVLQAELAGHEDAVQAVLFDPAGQYLVSCGSDNTFRLWS
What are the official names of this protein?
Flagellar WD repeat-containing protein Pf20.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum.
Protein: YIM11_LACTC
Sequence: MSESVANRAVVFYNNKSLPIISSEELNLDSCYSSSEVVIRVHAAALNPVDFLLQSFAYSWLVGRGPKTFSRDYSGEVVRAGANVKDFKVGDKVSGLFQHLYGKQGTLCDYLILDPVKQPAISKLAAAGHAEYDDYVVNAAWPLVFGTAYQGLTNFGQKLGPDSKILVIGASTSVSNAFVQIAKNHLKVGTVVGICSKKSFDYNKKLGYDYLAAYDDGSVVDSVKDIIGKNLNNEKFDLIFDSVGNSDFFGCINDVLKDKGQNSQFVSLTGDKKMNYSSPRIWDSLPGLESLKRYGPFRKYNYNLFMLRSDSAFMKLGYEMISEKQYMPAIDSVYSFDDYAKAFERVKSNRSKGKVVIKIH
What are the official names of this protein?
Protein YIM1-1.
What is the protein family that this protein belongs to?
Belongs to the YIM1 family.
What are the subcellular locations of this protein?
Lipid droplet. Mitochondrion.
Protein: DNAJ_LACP7
Sequence: MADKRDYYEVLGISKSASDDEIKKAYRKLAKQYHPDANPGDQTAEAKFKEASEAYAVLSDPEKKRQFDQFGHAAFEQGGGGAGGFDFNMGDMGDIFGDIFGDIFGGGRRSRASNGPMNGANLRTAIRITFEEAVFGCEKELELSLKDECETCHGSGAKPGSSAETCHKCNGKGQVTFTQQSLFGMVRNVQTCPDCRGTGKIIKEKCPDCYGSGYISRKKKIQVSVPAGIDNGQSIRIRGKGEPGTNGGERGDLLVEVNVSRHPIFQRQDYDIYSTAPMTFTQAALGGDVRISTVDGDVLYEVKPGTQTDTKVRLRGKGVPTLRNKDVRGDHYVTLVVQVPTKLNNEQKDLLKKFEESVSGKKSEDTTTEDTKEKKKKFFGK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM34_NEOFI
Sequence: MAFNFNWSPLMADASFYTRAQDLLTAALNKSPKPPIIVDDIIVTELNLGSIPPELEILEIGDLAEDRFRGIFKMSYSGDAFLTLKTRVQANPLNTYLLTRPSFATPRPLAAATPLTIPLQITLSDFKLSGFVILVFSKQKGITVVFRNDPLESLKVSSTFDSIPFVRDFLQKEIEAQLRILFMDELPAIIHRLSLRLWVPEYRAGEELQTQTESANGEGPGQDPLASPPQDPVDALGNALNESEIESLSLDSSVETHSLFSQKNLLRLAALTDSQRTLSLFTPSIREVVYRAWTSPSDQTDASGGVTSPFSPVLSRTQSQVGSMSSFPDSASMVSNQSRSSTPSHTFSGYGLSLGAGRHSKAHARKRKKRVVDLRRPKTTDDAPSVSDESAFTESTSTPSICSAPMPVLDEQTDDPVTPPLSPDRDLHLPAIPERHGMSISRPALRREIASEMIRDTAESKPSSNPVGQAIQDEDLSATPRAAVRAHGASVLEKEKQATGSSAGSSRQLPSTILPFINDSPTGRVVDQALVERLAGEIARRMRDEKFLASNACGPFWDRHSQEESPPPAYGH
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: YNEQ_BACSU
Sequence: MAFGVKREELNRWKQAVKRGEIAFLTHYWLDDRFPEAKTVTKAGCADIDKLVQWGAAYGLKKEWIHKKSEFPHFDLLGETQKYILEQENLTDHLIRFHL
What are the official names of this protein?
Uncharacterized protein YneQ.
Protein: SYGB_STRPI
Sequence: MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAIQTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVEDIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVHTLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCEREQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTSMKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQKLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIYKFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAVLAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYALKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEVSKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQLKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P4HA_DICDI
Sequence: MDISNLPPHIRQQILGLISKPQQNNDESSSSNNKNNLINNEKVSNVLIDLTSNLKIENFKIFNKESLNQLEKKGYLIIDNFLNDLNKINLIYDESYNQFKENKLIEAGMNKGTDKWKDKSIRGDYIQWIHRDSNSRIQDKDLSSTIRNINYLLDKLDLIKNEFDNVIPNFNSIKTQTQLAVYLNGGRYIKHRDSFYSSESLTISRRITMIYYVNKDWKKGDGGELRLYTNNPNNTNQKELKQTEEFIDIEPIADRLLIFLSPFLEHEVLQCNFEPRIAITTWIY
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline.  Probably hydroxylates skp1 on Pro-143.
What are the official names of this protein?
Prolyl 4-hydroxylase subunit alpha, Prolyl 4-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_HELPH
Sequence: MKTSKTKPPKSVLIAGPCVIESLENLRSIAIKLQPLANNERLDFYFKASFDKANRTSLESYRGPGLEKGLEMLQIIKEEFGYKILTDVHESYQASVAAKVADILQIPAFLCRQTDLIVEVSQTNAIINIKKGQFMNPKDMQYSVLKALKTRDSSIQSPTYETALKNGVWLCERGSSFGYGNLVVDMRSLTIMREFAPVIFDATHSVQMPGGANGKSSGDSSFAPILARAAAAVGIDGLFAETHVDPKNALSDGANMLKPDELERLVTDMLKIQNLF
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXE1_DANRE
Sequence: MSLNYIKNFYEGCLRPPTVIGQFHTLFFGSVRTFFLGVLGFAVYGNEALHFSCDPDKRELNLYCYNQFRPITPQVFWALQLVTVLVPGAVFHLYAACKNIDQEEILHRPMSTVFYIISVLLRIILEVLAFWLQSHLFGFLVDPIFMCDVTGLGKILNVSKCMVPEHFEKTIFLSAMYTFTIITILLCIAEIFEILFRRLGYLNQPMT
What is the function of this protein?
Has significant hemichannel activity.  However, has only low-efficiency gap junction activity and probably does not function as a gap junction channel in vivo.
What are the official names of this protein?
Gap junction epsilon-1 protein, Connexin-23.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Beta-type (group I) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYQ_AZOVD
Sequence: MSKPETPAAANFLRPIVQADLESGKHAKIVTRFPPEPNGYLHIGHAKSICLNFGLAQEFGGECNLRFDDTNPAKEDQEYIDAIKSDVRWLGFQWAGEERYASSYFDQLYDWAIHLIEAGKAYVCDLSPDEAREYRGSLTEPGRNSPYRERSVEENLDLFARMRAGEFPDGARALRAKIDMAAPNMNLRDPILYRIRHAHHHQTGDKWCIYPSYDFTHGQSDAIEGITHSICTLEFEDHRPLYEWFLDNLPVPCRPRQYEFARLNLNYTITSKRKLKQLVDEGHVGGWDDPRMSTLSGYRRRGYTPASIRAFCDMIGVNRAGGVVDIGMLEFAIREDLDANAARAMCVLKPLKVVITNYPQGRVESLELPRHPKQDMGVRVLPFSREIYIDAGDFEETPPAGYKRLIPGGEVRLRGSYVIRADEAIKDEAGNIVELRCSYDENTLGKNPEGRKVKGVIHWVPLEGSIKCEVRLYDRLFKVANPEKSEEGGSFLDNINSGSLVVLTGCRAEPSLANARPEERFQFEREGYFCADLKDSRPGAPVFNRTVTLRDSWGQ
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_PELPD
Sequence: MQSQKIRIRLKAYDHKLLDVSVTEIVDTAKRTGARVAGPIPLPTVINKYCVLRGPHVDKKSRDQFEIRTHKRLIDILDPTQQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.