PharMolix/UniProtQA huggingface dataset:
Protein: PGK_ACTP2
Sequence: MSVIKMADLDLAGKRLFIRADLNVPVKDGKVTSDARIRATIPTLKLALQKGAKVMVTSHLGRPTEGVFEEANSLQPVVDYLNASDLGVPVRLVRDYLDGVEVAENEIVVLENVRINKGEKKNDPELAKKYAALCDVFVMDAFGTAHRAEGSTYGVAEYAPVACAGPLLAAELDALGKALKEPQRPMLAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAEGHPVGKSLYEADLIPEAKRLAAATNIPVPVDVRVGTEFSEIAPATEKAVSEVQADESIFDIGDKSAEELANIIKSAKTILWNGPVGVFEFPNFRKGTEVISNAIAEATANGAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVEILEKRANG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROQ_YERPA
Sequence: MENQPKLNSSKEVIAFLAERFPLCFTAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSALRLYTSSWRYLYGVKVGAERVDLDGNPCGVLEEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAIAAGETPEPRRPRPAGKKPAPRREAGAAPENRKPRQSPRPQQVRPPRPQVEENQPRPVPVTDISKLQIGQEIKVRAGKSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQHA_SALTI
Sequence: MERFLENVMYASRWLLAPVYFGLSLALIALALKFFQEILHVLPNVFALAEADLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISAGKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDARNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OTUL_MOUSE
Sequence: MSRGTMPQPGAWPGASCAETPAREAGAAARDGGKVTAGAQPRAATRCPAEHEEDMYRAADEIEKEKELLIHERGISEPRLSVAPEMDIMDYCKKEWRGNTQKATCMKKGYEEVSQKFTSIRRVRGDNYCALRATLFQAMSQLAELPPWLQDLELILLPEKLINKYTWIKQWKLGLKFDGKSEDLVEKIKESLALLRKKWVSLAAMKTAEARQTACDELFTNEEEEYSLYEAVKFLMLNRAIELYDDKEKGKEVPFFSVLLFARDTSNDPEQLLRNHLNQVGHTGGLEQVEMFLLAYAVRHSIRVYRLSKYNTEEFITVYPTDPPKDWPMVTLIAEDDRHYNIPVRVCEETSV
What is the function of this protein?
Deubiquitinase that specifically removes linear ('Met-1'-linked) polyubiquitin chains to substrates and acts as a regulator of angiogenesis and innate immune response (PubMed:23708998, PubMed:27523608, PubMed:29950720).  Required during angiogenesis, craniofacial and neuronal development by regulating the canonical Wnt signaling together with the LUBAC complex (PubMed:23708998).  Acts as a negative regulator of NF-kappa-B by regulating the activity of the LUBAC complex (By similarity).  OTULIN function is mainly restricted to homeostasis of the LUBAC complex: acts by removing 'Met-1'-linked autoubiquitination of the LUBAC complex, thereby preventing inactivation of the LUBAC complex (PubMed:29950720).  Acts as a key negative regulator of inflammation by restricting spontaneous inflammation and maintaining immune homeostasis (PubMed:27523608, PubMed:29950720).  In myeloid cell, required to prevent unwarranted secretion of cytokines leading to inflammation and autoimmunity by restricting linear polyubiquitin formation (PubMed:27523608).  Plays a role in innate immune response by restricting linear polyubiquitin formation on LUBAC complex in response to NOD2 stimulation, probably to limit NOD2-dependent pro-inflammatory signaling (By similarity).
What are the official names of this protein?
Ubiquitin thioesterase otulin, Deubiquitinating enzyme otulin, OTU domain-containing deubiquitinase with linear linkage specificity, Ubiquitin thioesterase Gumby.
What is the protein family that this protein belongs to?
Belongs to the peptidase C65 family. Otulin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_CHLAT
Sequence: MTDILTNMFTIVAELPLGEEEGFAFNGNILETNLINLAAVIGLLFYSGRSFLTNLLRNREDNILKSIRDADERYKEATEKLQQAKNEFEQAKIEADEIRAQSRITAKEIEVSLMGLVSEDTKRLIDMKQATISFEEEKAINEVRRQVIRLALQRALEQSKNRLNHRLQKRVTRLNIGLLGQLVGVND
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MEP1A_MOUSE
Sequence: MLWIQPACLLSLIFSAHIAAVSIKHLLNGSDHDTDVGEQKDIFEINLAAGLNLFQGDILLPRTRNAMRDPSSRWKLPIPYILADNLELNAKGAILHAFEMFRLKSCVDFKPYEGESSYIIFQKLSGCWSMIGDQQVGQNISIGEGCDFKATIEHEILHALGFFHEQSRTDRDDYVNIWWDQIITDYEHNFNTYDDNTITDLNTPYDYESLMHYGPFSFNKNESIPTITTKIPEFNTIIGQLPDFSAIDLIRLNRMYNCTATHTLLDHCDFEKTNVCGMIQGTRDDADWAHGDSSQPEQVDHTLVGQCKGAGYFMFFNTSLGARGEAALLESRILYPKRKQQCLQFFYKMTGSPADRFEVWVRRDDNAGKVRQLAKIQTFQGDSDHNWKIAHVTLNEEKKFRYVFLGTKGDPGNSSGGIYLDDITLTETPCPAGVWTIRNISQILENTVKGDKLVSPRFYNSEGYGVGVTLYPNGRITSNSGFLGLTFHLYSGDNDAILEWPVENRQAIMTILDQEADTRNRMSLTLMFTTSKNQTSSAINGSVIWDRPSKVGVYDKDCDCFRSLDWGWGQAISHQLLKRRNFLKGDSLIIFVDFKDLTHLNRTEVPASARSTMPRGLLLQGQESPALGESSRKAMLEESLPSSLGQRHPSRQKRSVENTGPMEDHNWPQYFRDPCDPNPCQNEGTCVNVKGMASCRCVSGHAFFYAGERCQAMHVHGSLLGLLIGCIAGLIFLTFVTFSTTNGKLRQ
What are the official names of this protein?
Meprin A subunit alpha, Endopeptidase-2, MEP-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CPM_GLRV3
Sequence: MGAYTHVDFHESRLLKDKQDYLSFKSADEAPPDPPGYVRPDSYVRAYLIQRADFPNTQSLSVTLSIASNKLASGLMGSDAVSSSFMLMNDVGDYFECGVCHNKPYLGREVIFCRKYIGGRGVEITTGKNYTSNNWNEASYVIQVNVVDGLAQTTVNSTYTQTDVSGLPKNWTRIYKITKIVSVDQNLYPGCFSDSKLGVMRIRSLLVSPVRIFFRDILLKPLKKSFNARIEDVLNIDDTSLLVPSPVVPESTGGVGPSEQLDVVALTSDVTELINTRGQGKICFPDSVLSINEADIYDERYLPITEALQINARLRRLVLSKGGSQTPRDMGNMIVAMIQLFVLYSTVKNISVKDGYRVETELGQKRVYLSYSEVREAILGGKYGASPTNTVRSFMRYFAHTTITLLIEKKIQPACTALAKHGVPKRFTPYCFDFALLDNRYYPADVLKANAMACAIAIKSANLRRKGSETYNILESI
What is the function of this protein?
Minor capsid protein that encapsidates the 5'-terminal portion of the viral genome.
What are the official names of this protein?
Minor capsid protein, CPm.
What is the protein family that this protein belongs to?
Belongs to the closteroviridae minor capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: APT_BRADU
Sequence: MTFDHDLKASVRTIPDYPKPGIMFRDITTLLADARAFRRAVDELVNPWAGNKIDKVAGMEARGFIIGGAVAHQLSAGFVPIRKKGKLPHTTVRIAYSLEYGIDEMEMHVDAIQPGERVILVDDLIATGGTAEGAVKLLRQIGANVVAACFIIDLPELGGAAKLRAMDVPVRTLMTFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YVDE_LACLC
Sequence: MAIIGILGTPYNTVERSPFWWNKVSYTRQSFIDVFQELGHTVIVLPVDKTENIKNYLPLVDKIVLTGGVDVSPYLYGEEPHAQLGTTDPIRDRFELAAIKAALEANKPILGVCRGLQLLNVYFGGTLYQDLSLTSSQIKHLQSPTPQEVPTHHISVEKEDSFRFLPENYMVNSFHHQVIKDLGQGLQA
What are the official names of this protein?
Putative glutamine amidotransferase-like protein YvdE homolog.
Protein: SYFA_BACHK
Sequence: MEARLKELKQKALELIEEAKELKGLNDVRVAYLGKKGPITEVLRGMGKLSAEERPRMGALVNEVREAIQTRLDDKISNLEKAVIEAKLATETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFGEDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTM1_SCLS1
Sequence: MAQGQVQVYFTTTSPDIQLPEEKQQLLVPTNVRRYGLSQILNSEAMLDTSSPIPFDFLINGTFLRTTLDEYLTANGLSSETTLNLQYVRSLIPPLYEASFEHDDWVSSVDVYSGSSAVGIWGSSSVEAGQERILSGSYDGLLRVWNKSGQAIATSAPASAGGHTSGVKSAKFLSTKQIASAGLDRTIRIWNYSEAEDHFSAQLKPTLELYGHTGSIDSIAVHGPSNRILSASADGQIGFWTSHKSSAPEVNASLISGPSAKRRKITTSTSTPQRGPLSLMDCHNGPATAVIFNPEDSTVAYSASQDHTIKTLDITTSSIVDTRTLLNPILSLCALPGIGHQIIAAGTTARHIALIDPRASAATTQAMTLRGHTNFVSSIFADPDSNYGLVSAGHDGTCRVWDLRSTRQGTKDEGLGVVGEAIYIIERESRKDKTTKPVGGEGVKVFDVNWDKDVGIVSAGEDKMVQVNKGRGVTRPEI
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ytm1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: CO9A2_BOVIN
Sequence: MAPAADPRSLLVLLQVLGLALAQIRGLPGEPGPPGPPGPPGVPGSDGIDGDKGPPGKAGPPGPKGEPGKAGTDGPDGKPGIDGLTGAKGEPGPAGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGLTGPKGDPGPEGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPAGVKGPPGLQGVKGHPGRRGLLGDSGRQGKPGPKGDVGASGEQGIPGPPGPQGVRGYPGMAGPKGETGPQGYKGMVGSVGAAGSPGEEGPRGPPGRAGEKGDVGSQGVRGPQGITGPKGATGPPGIDGKDGTPGTPGVKGSAGQAGRPGNPGHQGLAGVPGMPGTKGGPGDKGEPGRQGFPGVSGPPGKEGEPGPRGEIGPQGIMGQKGDHGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGIKGDKGSPGKTGPRGGVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLVGDRGLPGQPGRQGVAGRDASDQHIEDVVLKMLQEQLAEMAVSAKREALGATGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDQGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGAPGAPGEAGRPGLPGPIGLPGFCEPAACLGASAYASGRLTEPGSIKGP
What is the function of this protein?
Structural component of hyaline cartilage and vitreous of the eye.
What are the official names of this protein?
Collagen alpha-2(IX) chain, Collagen type IX alpha 2 chain.
What is the protein family that this protein belongs to?
Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MSRP_PSEAE
Sequence: MLIKIPSRSDCSESEVTSETLYLSRRRLLGASFAGLALASGLPRLGFADEQRYAGVESVPAPGWFAEKLPQTRWQAVNVQGEAITPFKDATHYNNFYEFGPNKGDPAENASALKAEPWSVVIDGEVGKPGTYALEDFVKPYQLEERIYRLRCVEAWSMVIPWLGFPLADLLKRVEPNGQAKFVRFETLQRPEQMVGQRSGFSVIDWPYMEGLRMDEAMHPLAILAVGMYGRLLPNQNGAPLRLVVPWKYGFKSIKSIVRISLVREQPKTTWESIAANEYGFYANVNPQVDHPRWSQARERRLPSGLFSPNVRDTQMFNGYGSEVASLYSGMDLRKYY
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: PYRG_HAHCH
Sequence: MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKVTILKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIRTTMTKRNNFTTGRVYETVLRKERRGDYLGGTVQVIPHITDEIKRRIVEGAGDADVALVEIGGTVGDIESLPFLEATRQLKVEVGSRRALFMHLTLVPYIATAGEVKTKPTQHSVKEMRSIGLQPDILVCRSEHSIDQSSRRKIALFTNVEERAVIALEDAKSIYSIPMMLHAQGLDEIIVERFGLECGPADLSEWQSVVDNEANPEHEVTIAMVGKYMELLDAYKSLIEALKHAGIRNKTKVNIRYIDSEQVYQQGVDLLKGVDAILVPGGFGERGVEGKIQTVRYARENKIPYLGICLGLQVAVIEYARHVAGMEDAHSTEFNPKSAHPVVGLITEWQDASGKTEQRDEASDLGGTMRLGAQECKLVDGSTVRECYGKAIIEERHRHRYEVNGNLVPRLEEAGLQVAGWSQDGSLVEVVEVKDHPWFVACQFHPEFKSTPRDGHPLFEGFVRAALENAGGK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TRMB_DROYA
Sequence: MVATGGQAQDQSHNQEPGVLCPTSAVTGLPQKRYYRQRAHSNPIADHSFDYPARPEDVDWRSMYPSIQQGQQVSFADIGCGYGGFLITLGEMFPEKLSIGMEIRVKVSDYVVDRIAALRRKGADTGAYQNVACLRTNAMKYLPNYFAKGQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYVLRKGGLVYTMTDVEDLHKWIVAHMEEHPLYERLTEEEANADPITPKLYQSSEEGAKVVRNKGDHFLAIFRRL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TNRA_BACSU
Sequence: MTTEDHSYKDKKVISIGIVSELTGLSVRQIRYYEERKLIYPQRSSRGTRKYSFADVERLMDIANKREDGVQTAEILKDMRKKEQMLKNDPQVRKKMLEGQLNAHFRYKNR
What is the function of this protein?
Transcription regulator that actives the transcription of genes required for nitrogen assimilation such as nrgAB (ammonium transport), nasABCDEF (nitrate/nitrite assimilation), ureABC (urea degradation) and gabP (GABA transport), during nitrogen limitation (PubMed:8799114, PubMed:9603886, PubMed:10231480, PubMed:10864496, PubMed:11719184, PubMed:12823818).  Also represses glnRA and gltAB in the absence of ammonium (PubMed:8799114, PubMed:9603886, PubMed:10231480, PubMed:10864496, PubMed:11719184, PubMed:12823818).  On the contrary of the MerR members, which require longer DNA sites for high-affinity binding, TnrA requires a DNA sequence of 17 nucleotides as minimal binding site (PubMed:10231480, PubMed:25691471).
What are the official names of this protein?
HTH-type transcriptional regulator TnrA, Transcriptional nitrogen regulatory protein A, TnrA.
What are the subcellular locations of this protein?
Cell membrane. Note=Under poor nitrogen source such as nitrate, TnrA is associated with the cell membrane via the ammonium uptake proteins AmtB and its cognate regulator GlnK (PubMed:21435182). Without usable nitrogen source, TnrA is released from the membrane to the cytoplasm where it is degraded by proteolysis (PubMed:21435182). The presence of 4 mM ATP leads to concomitant solubilization of GlnK and TnrA (PubMed:17001076). GlnK and Amtb are required for the membrane association of TnrA (PubMed:17001076).
Protein: GCST_BACAA
Sequence: MITLQRTPLFDVYAKYGGKTIDFGGWELPVQFSSIKEEHEAVRTAAGLFDVSHMGEVEVKGVDSLAFLQRVVTNDVSTLKVGGAQYTAMCYENGGTVDDLLIYKRGEEDYLLVINASNIEKDYEWLASHVIGDATVVNVSSEVAQLAIQGPKAEGILQKVVSEDLKEIKFFKFKNDILVDGIPALVSRTGYTGEDGFEIYCKSEDAAKLWEKLLEVGAEEGLKACGLGARDTLRFEATLPLYGQELSKDITPIEAGIGFAVKTNKEADFFGKATLKEQKENGAPRKLVGIEVIERGIPRTHYPVFIGEEKIGEVTSGTQSPTLKKSIGLALIDVKYAAVDTEVEIEIRNKRVKAVVVPTPFYKRSK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: FLA7_ARATH
Sequence: MAKMQLSIFIAVVALIVCSASAKTASPPAPVLPPTPAPAPAPENVNLTELLSVAGPFHTFLDYLLSTGVIETFQNQANNTEEGITIFVPKDDAFKAQKNPPLSNLTKDQLKQLVLFHALPHYYSLSEFKNLSQSGPVSTFAGGQYSLKFTDVSGTVRIDSLWTRTKVSSSVFSTDPVAVYQVNRVLLPEAIFGTDVPPMPAPAPAPIVSAPSDSPSVADSEGASSPKSSHKNSGQKLLLAPISMVISGLVALFL
What is the function of this protein?
May be a cell surface adhesion protein.
What are the official names of this protein?
Fasciclin-like arabinogalactan protein 7.
What is the protein family that this protein belongs to?
Belongs to the fasciclin-like AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: ARP10_PIG
Sequence: MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSLNNPPLEMVFDVGKSQPPLMKRAFSTEK
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Actin-related protein 10.
What is the protein family that this protein belongs to?
Belongs to the actin family.
Protein: PSBK_JASNU
Sequence: MLNIFSLISICLNSALYSSSFFFGKLPEAYAFLNPIVDVMPVIPVFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: S35D2_MOUSE
Sequence: MEEPNAAPLPSRLARLLSALFYGTCSFLIVLVNKALLTTYGFPSPIVLGIGQMATTIMILYVFKLNKIIHFPDFDKKIPGKLFPLPLLYVGNHISGLSSTSKLSLPMFTVLRKFTIPFTLLLEAIILGTQYSLNIILSVLAIVLGAFIAAGSDLTFNLEGYVFVFLNDIFTAANGVYTKQKMDPKELGKYGVLFYNACFMLIPTVIISVSTGDFQQATEFRHWKNVLFIIQFLLSCLLGFLLMYSTALCSYYNSALTTAVVGAIKNVSVAYIGMLVGGDYIFSLLNFIGLNICMAGGLRYSFLTLSSQLKPKQPVDEESIPLDLKS
What is the function of this protein?
Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars).  May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter, Solute carrier family 35 member D2, UDP-galactose transporter-related protein 8, UGTrel8.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RBSD_LACLA
Sequence: MKKEGILNSELAKIADDLGHTDQVCIGDLGLPVPSGVKKIDLALTRGKPSFQEVLDIYLENILVEKVYLAEEIKENNPEQLAILLTKLSADVEIVFVSHETLKLMNHEVKAVVRTGENTPYSNIILQSGVAL
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRG20_CAEEL
Sequence: MSTRLIIPANFSYDDPLPFTCNQDSHVMLSILEYLVQATYLSVSAVLNSMIVYTIFRCKGKHSYRRNPFFVLYAAEAVMNVYSCVIEVLFGRLIIYMTPLCPALSPFFFTPSILTKLYFLLNHYCLAFKTLSQIAISFNRMTCVIFPVHHFKLWQNILAPVLVSLFVLPLGVTWNILVSRVYVNPNGAGFSVNYRDAVAWANISFLHLFHCIPCLFLMIVFFLASIFGLTMLENRLRSAERSLIIFTMTLGVETMLFAIAQIYFAFLAGYLPGIRPLMLLISFNVFDVLYVYSPIALILMNRQLRRDIFHLKGDDPGFGFTKFPVILVEMISDSSPHLLIINLQLV
What are the official names of this protein?
Serpentine receptor class gamma-20, Protein srg-20.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srg family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PURR_SERP5
Sequence: MATIKDVAKRAGVSTTTVSHVINKTRFVAEETKAAVGAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAPYFAEVIEAVENSCYSKGYTLILCNSHNNLDKQRAYLAMLAQKRVDGLLVMCSEYPDQLLGMLEDYRNIPMVVMDWGAARGDFTDSIIDNAFAGGYLAGRYLIERGHRDIGAIPGQLSRNTGGGRHQGFLKAMEEANIEVRDEWIVQGDFEPESGYKAMHQILSQKHRPTAVFCGGDIMAMGAICAADELGLRVPQDISVIGYDNVRNARYFTPALTTIHQPKERLGEMAFTMLLDRIISKREESQVIEVHPKLIERRSVADGPFIDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: PUR3_STAAC
Sequence: MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRKCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
What is the function of this protein?
Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
What are the official names of this protein?
Phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase, GAR transformylase, GART.
What is the protein family that this protein belongs to?
Belongs to the GART family.
Protein: YCF48_TRIV2
Sequence: MVIVKSWQKIFALLVVLLLCIGCSKVPSTSYNPWAVVSLPTEAKLLDIAFTENPQHGFLVGSNATLLETNDGGNNWQPLNLALDDDRYRFDSVSFAGKEGWIAGEPSLLLHTTDEGRSWSRIPLSEKLPGNPIAIQALGTDIAEMATDVGAIYKTTDGGKNWKAQVEAAVGVVRNLERSEDGKYVAVSAKGSFYSTWEPGQNAWVPHNRNSSRRVENMGFSQDGLWLLARGGQVQFSDPTKPDEWLDAQTPELATSWGLLDMAYRTPNEVWIGGGSGNLLVSTDGGKTWEKDRDVEEVAANFYKVVFLKPDQGFVIGDRGVLLKYQPEAAKTATTEPAA
What is the function of this protein?
A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly.  Also plays a role in replacement of photodamaged D1 (psbA).  Assists YidC in synthesis of chlorophyll-binding proteins.
What are the official names of this protein?
Photosystem II assembly lipoprotein Ycf48.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Lipid-anchor; Lumenal side. Note=Associated with a PSII precusor complex on the lumenal side of the thylakoid membrane.
Protein: ILVC_ECO81
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.