PharMolix/UniProtQA huggingface dataset:
Protein: MINC_BACAN
Sequence: MEEKKQQNVTIKGTKDGITLHLDDCCSFSELLKELDEKLSTHYYDGDGRSLIEVHVKVGNRYLTEVQQEEIRTLIRNKKNLVVDSIESDVITKEEAIAWKEETEIVPISKIVRSGQVLHVKGNLLLIGDVNPGGTVIAGGNIFVVGSLRGIAHAGYYGDSDAVIAASVMNPMQLRISDVAMRAPEEKEDGAEAAECAYINENNHIVVDRLQLLTHLRPNLTKLERGIV
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: PYY_MOUSE
Sequence: MVAVRRPWPVTVAMLLILLACLGALVDAYPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRYGKRDVPAALFSKLLFTDDSDSENLPFRPEGLDQW
What is the function of this protein?
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
What are the official names of this protein?
Peptide YY, PYY, Peptide tyrosine tyrosine.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCS1_OCIBA
Sequence: MDVSILRDVRPPVTSYAPNIWADTFSNISLDEEVQKKYAETIEALKQVVRGMLMAAATPIKQMIFIDTLERLGLAYHFETEIEHKLQKIYDDNVCGDDCDLFTTALRFRLLRQHRHHVSCDVFDKFLYEEGKFKGDAEGLLSLYEASHVRFHNEKILEEAERFTRQELSCWIKLQSPLKDKVKRALERPLHREVPILYARHFISIYEKDESMDEHLLKLAKFNFNFLQNLYKKELYDLSRWWNKFDLKTKLPYIRDRLAEAYLWGVGYHFEPQYSYVRKGVVLSIKIIGILDDTYDNYATVNEAQLFTEILDRWSMDEIDRLPDYMKIVLHFVMSAYEEYERDAKIVYGKKFASPYFKETIQQLARGYNQELKWVMEKQMPPFKDYLKNSEITSCIYIMFASIIPGLKSFTQEAIDWIKNEPNFAVKAGLIGRYWDDIGSHKRESKGGEMLTVMDCYMKQYSVSIQETISEFAKAVEDSWKEVNEGWVYTISMSKEITVQFLNYSRMCDASYNRNNGDGYTDPSFAKSNITALFVDPIII
What is the function of this protein?
Sesquiterpene synthase that catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to gamma cadinene.
What are the official names of this protein?
Gamma-cadinene synthase, (+)-gamma-cadinene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: PMA7_ARATH
Sequence: MTDIEALKAITTESIDLENVPVEEVFQHLKCTKEGLTSNEVQERLTLFGYNKLEEKKESKILKFLGFMWNPLSWVMEAAALMAIGLAHGGGKPADYHDFVGIVVLLLINSTISFVEENNAGNAAAALMAQLAPKAKAVRDGKWNEIDAAELVPGDIVSIKLGDIIPADARLLEGDPLKIDQATLTGESLPVTKNPGASVYSGSTCKQGEIEAVVIATGVHTFFGKAAHLVDSTTHVGHFQKVLTAIGNFCICSIAVGMAIEIVVIYGLQKRGYRVGIDNLLVLLIGGIPIAMPTVLSVTMAIGAHRLAQQGAITKRMTAIEEMAGMDVLCSDKTGTLTLNKLSVDKNLIEVFKRGIDRDMAVLMAARAARLENQDAIDTAIVSMLSDPKEARAGIKELHFLPFSPANRRTALTYLDGEGKMHRVSKGAPEEILDMAHNKLEIKEKVHATIDKFAERGLRSLGLAYQEVPDGDVKGEGGPWDFVALLPLFDPPRHDSAQTIERALHLGVSVKMITGDQLAIAKETGRRLGMGTNMYPSSSLLSDNNTEGVSVDELIENADGFAGVFPEHKYEIVKRLQSRKHICGMTGDGVNDAPALKKADIGIAVDDATDAARGASDIVLTEPGLSVIISAVLTSRAIFQRMKNYTIYAVSITIRIVMGFMLLCVFWEFDFPPFMVLVIAILNDGTIMTISKDRVKPSPTPDCWKLKEIFATGVVLGAYLAIMTVVFFWAAYETNFFHNIFHVRNFNQHHFKMKDKKVAAHLNEQMASAVYLQVSTISQALIFVTRSRSWSFVERPGFLLVIAFLIAQLVASVISAMANWPFAGIRSIGWGWTGVIWIFNIVTYMLLDPIKFLVRYALSGKSWDRMVEGRTALTGKKNFGQEERMAAWATEKRTQHGLETGQKPVYERNSATELNNMAEEAKRRAEIARMRELQTLKGKVESAAKLKGYDLEDPNSNNYTI
What is the function of this protein?
The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport.  The resulting external acidification and/or internal alkinization may mediate growth responses (By similarity).
What are the official names of this protein?
ATPase 7, plasma membrane-type, Proton pump 7.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CONO1_CONML
Sequence: CFPGNCPDS
What is the function of this protein?
Shows reduced activity on vasopressin-oxytocin related receptors.  Is more active on fish receptors, than on their human counterpart, supporting an evolved role of this conopressin in the envenomation process.  Shows weak agonist activity on the zebrafish vasopressin receptor 1Ab (V1a1R) (EC(50)=13. 6 uM).  Also has weaker agonist activity on the human vasopressin receptor AVPR1B (EC(50)=38. 2 uM).  Has no effect on all other receptors tested.
What are the official names of this protein?
Conopressin-M1, Con-M1.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAZ_STAAT
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TSN7_PANTR
Sequence: METKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV
What is the function of this protein?
May be involved in cell proliferation and cell motility.
What are the official names of this protein?
Tetraspanin-7, Tspan-7, Transmembrane 4 superfamily member 2.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DAPB_AGRFC
Sequence: MGSSGMKLVVVGAAGRMGQALIRLIHQTPGVQLHAAVAREGSAFVGRDAGEIAGLGPIGIEITSDPLQAFLHAEGVIDFTSPATSITFAGLAAQARIVHVVGTTGCSPQDEEKFKAASRHARIVKSGNMSLGVNLLSVLTQQAAQALDAQNWDIEILEMHHKHKVDAPSGTALLLGEAAAAGRKVDLTAASVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVIFAGEGERVELSHYAGDRSIFARGAITAAVWAFDKKPGFYSMLDVLGLSQAE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSPA5_BORBG
Sequence: MKKYLLGIGLILALIACKQNVSSLDEKNSVSVDLPGEMKVLVSKEKDKDGKYSLMATVDKLELKGTSDKSNGSGTLEGEKSDKSKAKLTISEDLSKTTFEIFKEDGKTLVSKKVNSKDKSSIEEKFNAKGELSEKTILRANGTRLEYTEIKSDGTGKAKEVLKDFALEGTLAADKTTLKVTEGTVVLSKHIPNSGEITVELNDSNSTQATKKTGKWDSNTSTLTISVNSKKTKNIVFTKEDTITVQKYDSAGTNLEGNAVEIKTLDELKNALK
What are the official names of this protein?
Outer surface protein A.
What is the protein family that this protein belongs to?
Belongs to the OspA lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: HIS21_RHOPA
Sequence: MARFTLHDLAATVDARAASGGESSYTKKLLDKGPEHCAKKFGEEAVEMVIAAVENDRGHLISETADVLFHMLVLLKSRGVKLEEVEAALAQRTSMSGLEEKASRKRD
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase 1, PRA-PH 1.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_RHOJR
Sequence: MNGDKSTLSVIVAGGGTAGHIEPALAVADAIKAIDDTAVVTALGTARGLETTLVPERGYPLELIPPVPLPRKPTLDLLRLPGRVRASVRRTREVLDATGADVVVGFGGYVALPAYLAAGPGLLRRRRRIPIVVHEANASAGIANKIGARRAARVLAAVAGSGVSARGRSDAEILGIPVRASITALDRAALRAEARAHFGLPADGPVLLVFGGSQGARSLNEAVSGAAESLAAAGVAVLHAHGPKNTLDVPATPGGPPYVAVPYLSRMDLAYSAADAVICRSGAMTVAEVSAVGLPAVYVPLPHGNGEQELNARPVVAAGGGMIVADGDLSAGFVAETVIPLLRDPAQLEDMGRRAAGAGHRSAATEVARIVLDVAALTRGTR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KLDC4_MOUSE
Sequence: MGKKGKKEKKGRGAEKTAAKMEKKVSKRSRKEEEDLEALIAHFQTLDAKKTQVTETPCPPPSPRLNASLSAHPEKDELILFGGEYFNGQKTFMYNELYIYSIRKDTWTKVDIPGPPPRRCAHQAVVVPQGGGQLWVFGGEFASPDGEQFYHYKDLWVLHLATKTWEQIRSTGGPSGRSGHRMVAWKRQLILFGGFHESARDYIYYSDVYTFSLDTFQWSKLSPSGAGPTPRSGCLMAVTPQGSIAIYGGYSKQRVKKDVDKGTQHSDMFLLKPAEGGEGKWAWTRINPSGVKPTARSGFSVAVAPNHQILVFGGVCDEEEEESLEGSFFSDLYIYDAAKSRWFAAQLKGPKSEKKKRRRGKAEDPEGTTEQETGGSSAPEPLEVIKEVVSEDGTVVTIKQVLTPSGLGVQPSPKADDSASEASSTGQEPCPRSNAMLAVKHGLLYVYGGMFEAGDRQVTLSDLYCLDLHKMEEWKTLVEMDPKSQEWLEESDSEEDSSSDEESEDGEDKDQEDSAEEGADPQHPEVARGEQFEEYLSRTEQHWLKLARSHVGPEAKEKKVLKVAQAMAKSCFDDAVQDIAQARH
What are the official names of this protein?
Kelch domain-containing protein 4.
Protein: Y1880_STRPF
Sequence: MLTFLIPTAKEMVIPKESYPHLLPQPSQAILKAMAAMTTEDLAKAYRIKEEAAKKEQQRWQDMTSQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQVYITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSSEFDDVFSKDCKQLWIGPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKSLVFAGFYYHPDLSTDHEFVYIKKEA
What are the official names of this protein?
UPF0246 protein MGAS10750_Spy1880.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SPCS2_XENTR
Sequence: MAARGGKNGLLEKWKIDDKPVKIDKWDGSAVKNSLDDAAKKVLLEKYRYVENFCLIDGRLIICTISCVFAIVALVWDYLHPFPESKPVLAICVISYFLMMGILTIYTSYKEKSIFLVAHRKDPAGMDPDDIWHLSSSLKRFDDKYTLKVTYISGKTKAQRDAEFTKSIARFFDDNGTLVMDLFEPEVSKLHDSLAMEKKTK
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 2, Microsomal signal peptidase 25 kDa subunit, SPase 25 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GSH1_SALA4
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVTEGEAAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYARIGVEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLKRVAQTLDSIHGGEEYQKVCDELVACFDNPELTFSARILRSMIDEGIGGTGKAFGEAYRNLLREEPLEILQEEEFIAERDASVRRQQEIEAADTEPFAAWLAKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: AEEP_ECOLI
Sequence: MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEEGIKGTGECTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGAARNALDCALWDLAARRQQQSLADLIGITLPETVITAQTVVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISERMVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIHPLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFSLMLGCMLCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL
What is the function of this protein?
Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has a role in the recycling of the murein peptide, of which L-Ala-D-Glu is a component.  Is also able to catalyze the reverse reaction and the epimerization of all the L-Ala-X dipeptides, except L-Ala-L-Arg, L-Ala-L-Lys and L-Ala-L-Pro.  Is also active with L-Gly-L-Glu, L-Phe-L-Glu, and L-Ser-L-Glu, but not with L-Glu-L-Glu, L-Lys-L-Glu, L-Pro-L-Glu, L-Lys-L-Ala, or D-Ala-D-Ala.
What are the official names of this protein?
L-Ala-D/L-Glu epimerase, AE epimerase, AEE.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: MOAA_SALPK
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPGGVTNNGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVGENDAIRQIAVTTNGYRLARDAANWREAGLTGVNVSVDSLDARQFHAITGQDKFRQVMAGIDAAFDAGFEKVKVNTVLMRDVNHHQLDTFLAWIQPRPIQLRFIELMETGEGSDLFRKHHISGQVLRDELIKRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGDGGVSLRDLLQDDAQQYALEERISDALREKKQTHFLHQSNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: MBP_BOVIN
Sequence: AAQKRPSQRSKYLASASTMDHARHGFLPRHRDTGILDSLGRFFGSDRGAPKRGSGKDGHHAARTTHYGSLPQKAQGHRPQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPGFGYGGRASDYKSAHKGLKGHDAQGTLSKIFKLGGRDSRSGSPMARR
What is the function of this protein?
Is, with PLP, the most abundant protein component of the myelin membrane in the CNS.  Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers.  Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
What are the official names of this protein?
Myelin basic protein, MBP, 20 kDa microtubule-stabilizing protein, Myelin A1 protein.
What is the protein family that this protein belongs to?
Belongs to the myelin basic protein family.
What are the subcellular locations of this protein?
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
Protein: TSAD_MARSD
Sequence: MLCLGIESSCDETGLALVRDGKLVAEKLASQVDVHAVFGGVVPEIASREHLRVLPVLLRELLKEQRLTIDDIDVVSVARGPGLQGCLLMGLSFAKGLVLSCGAKLVGVNHLWAHLTAAGLEQDLQFPSLGLLVSGGHTHIYLIESPLQFTLLGRTLDDAAGEAFDKTAKSLNLPYPGGKLVDDLGRQGVVNKKLFPVPYINNDNLDFSFSGLKTAVANYVNQNSNLRLDTMGIPEEGVEEPAISEERKNMLASFNYTVGRTLEVKVERALKRNRGVKSLIVAGGVAANSVVRSVMTDVAAKFSIPLVLPSMHLCTDNGAMIAYAGYLMASAGCRHDLDLDAIPRGRVIPSDWICEG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSIC_ECOLI
Sequence: MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEADAQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLTITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEILLFSLEFILINLVVDVLYAAINPAIRYK
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_METPE
Sequence: MKDFISIRDFDRAAIDRLIAEAERIDHHQYDPLEMKGKILALLFFEPSTRTRMSFEAAMARLGGTSLTLSSFEASSMAKGETLADTIRVVSGYVDAIVLRHPREGAARLASEVSSVPVINAGDGAGQHPSQTLLDLYTIRQSMPIDGINIGLLGDLRYGRTTHSLTYALSLYDAVIHTVAPAGLNLPSGLVHELRELGTEVIEHEQIEDVIKELDVLYVTRIQRERFPDTASYFNVASSYRITPELLRGTKEHMVVLHPLPRVDEIDPRVDKMKNARYFEQSHNGVPVRMAMLKQVIA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: EF2_NATPD
Sequence: MGRRKKIVQECERLMDEPEQIRNIAIAAHVDHGKTTLTDNLLAGAGMISDETAGEQLAMDTEEDEQERGITIDAANVSMTHEYEDENHLINLIDTPGHVDFGGDVTRAMRAVDGALVVVDAVEGAMPQTETVLRQALREGVKPTLFINKVDRLISELQEGPEEMQQRLTGVIGDVNELIRGMTEEMDDINEDWTVSVEDGTVGFGSALYKWGVSMPSMQRTGMDFGEIIELERADKRQELHERTPLSDVVLDMVCEHFPNPVDAQPRRIPRIWRGDADSEVAEAMELVNEDGELVMMVTDIGIDPHAGEIAAGRVFSGTIEKGQDLYVSGTAGTNRVQSVGIYMGGEREEVERVPAGNIAAVTGLKDAIAGSTVSSVEMTPFESIEHISEPVITKSVEAKNMDDLPKLIETLQQVAKEDPTIQIEINEDTGEHLISGQGELHLEVITQRIERNQGIPVNTGEPIVVFREAPQQESREVEGRSPNNHNRFYITVEPLEDDIVETIKMGDVSMDMPELERREELMEQGMDKDTAQNVETIHNTNVFIDDTKGIQHLNETMELVVEGLEEALNDGPLAAEPVEGALIRLHDARLHEDAIHRGPAQVIPAVREAVHNALIDAEIKLLEPIQEVRIDVPNEHMGAASGEIQGRRGRVDDMYQEGDLMVVEGVAPVDEMIGFSSDIRSATEGRASWNTENAGFRVMADNLQPETIDEIRERKGMKLELPEQIDYF
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGF4_HUMAN
Sequence: MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPVAAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.  Required for normal limb and cardiac valve development during embryogenesis.
What are the official names of this protein?
Fibroblast growth factor 4, FGF-4, Heparin secretory-transforming protein 1, HST, HST-1, HSTF-1, Heparin-binding growth factor 4, HBGF-4, Transforming protein KS3.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACCA_AROAE
Sequence: MKTTFLDFEQPVADLEAKIEKLRFVQDDSAVDISEEIARLEAKSQTLSKNLYAKLTPWQIAQVSRHPQRPYTLDYARHIFTDFVELHGDRTYADDKAIVGGLARFNGQSCVVIGHQKGRDTKEKILRNFGMPRPEGYRKALRLMRLAEKFGLPVFTFVDTPGAYPGIDAEERGQSEAIGRNLYVMAELKVPIITTIIGEGGSGGALAIAVGDQVMMLQYATYSVISPEGCASILWKSAEKASEAAETMGITAARLKSLGLIDRVVNEPAGGAHRDHRAMAQTLKRALQDALRQVADLSPAELVEKRLERLMSYGRFKEQKVA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUBL_YERPN
Sequence: MSEALAVLPDDTFTREQAEVVAAQYTNVAIEDDQGAHFRLVVRQNGEMVWRTWNFEPGGTYWLNRYIADYGIRKPQ
What are the official names of this protein?
UPF0401 protein YubL.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: MNMA_PROM1
Sequence: MPMNVETRETKKVLNHLPSEETVEKTLKRLQTFSGDQSVVVGLSGGVDSSLTAALLCKAGWDVEGLTLWLMKGKGSCCSDGLVDAAGICDQLGIKHHIVDSKEIFQKEIINNVLKGYEEGITPLPCSRCNKSVKFSEMLKWVKENKNIEKIATGHYARIRYSNESFNENDLPSNGIKRHKLLRGKDLNKDQSYFLYDLPQEILGRTIFPLGELTKEITRIEALKHSLKTAKKPESQDLCLAEHYGSMNAFIDKYLPQKKGEVVLKSGQIIGSHNGIQHFTIGQRKGLGIAWEVPLHVVEIDASLNRVIVAPREDSGKSECIVKDINWVSIEAPQEPIKVEVQIRYRSKAVKAKLIPIFDSNKENYCYQCHIHFEEDQFSITPGQAAVFYMGDYVLGGGLISKEY
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TVP38_YEAS7
Sequence: MSQSYEAGNANMGQGEDDEFDGYFEDFDNDIMPNSNNGQRVGTNAGLSFNDEVNVNDDDFLDIYNMSPRERLMHNIRKNVQKLQFYFYSLRLWQQIIIVLLGIMLMIMGILLLVFHNAILHKVVVTSNDLREKMSTHFILMVLIFFVAFPPMIGYSLLSTTTGLIYGVSFEGWVTLALGSVTGSIASFVVFKTILHSRAEKLVHLNRRFEALASILQENNSYWILALLRLCPFPYSLTNGAIAGVYGISVRNFSIANIITTPKLFIYLFIGSRVKSLAESESTGSRVFDLVSIIITLLILSLTAWLLYFKTKKRYLELQNRDRQVSTDQLPELSFEV
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking and spindle migration.
What are the official names of this protein?
Golgi apparatus membrane protein TVP38, TLG2-vesicle protein of 38 kDa.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: YGFB_ECO81
Sequence: MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDSSWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH
What are the official names of this protein?
UPF0149 protein YgfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: CLPX_TROW8
Sequence: MTDDTEYRCSFCGKEHHQVDDLIAGPDVRICSECVVLSCEIVEDRRNEALAKQDAFIKRKQRSVLEGLPKPAEIYAFLDEYVIGQQKAKRDLSVAVYNHYKRLVSTKSESENEVELSKSNILLIGPTGCGKTYLAQTLARMLRVPFAVADATALTEAGYVGDDVENVLLKLLQDADFDITRAEAGIVCIDEIDKISRKADSPSITRDVSGEGVQQALLKILEGTAASVPLQGGKKHTQYEQASINTRNILFIVAGAFSGIEEIISSRIGRSNMGFGSDLLRKDTDVFDQILPEDLRKFGLIPEFIGRLPIVTAISHLDGEDMIRVLTEPKNALVKQYKRLFSLDGVSLGFDHEALEAIVELALKRKTGARALRSVMESILSPIMFDVPSRGDIESVRITAETVAGGGPHLTMRCARSNYIRSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YDDK_BACSU
Sequence: MDTLKKLKFEANGIIGVLLDYSREPVLTNIIDQFRTSLESNDIELIRYSLEQLKTWYARNRNEIYKNEFVFNEFEHHETENKIKKFLDELPVVDETEKSSITHFSSDQNRELEKKIFISHSSKDKIVCNAFVELLEDIGVSSEDIIYTSSPYHGIPGDEDIFEYLKKHLFKGAYVFYMLSDNYYDSVYCLNEMGATWVNSNNCSTFILPGFKGEIKGVIDKNKKAFSLEEPIDLFNLKEKILRMYDLTLEDKKWERIKAKFNTKLK
What are the official names of this protein?
Uncharacterized protein YddK.
Protein: SYR_LEGPC
Sequence: MKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPKVLAERLVAVIPSDPSVEKIEIAGAGFINFFMRNTARSLIISEILNKGKEFGRGNLGQSQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVTLEYYVNDAGRQMNILAVSVWLRYLELAGEPIVFPANGYKGQYVYEIAQEMWSEQGNQFVHPWISVVENLPADEPEGGDKETYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSIEKGIQALKDRGHTYEREGALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFAILYRGGDRVQMSTRSGSFVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLRQLKERGLKWDKDMGLKNLDLLEQQHETTLISLIARYPEVIQSAAASCEPHQLAYYLRELANGLHSYYNAIQLLCEQEQLRCARLCLLESVRQVLNNGLAILGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.