PharMolix/UniProtQA huggingface dataset:
Protein: ARGB_MYCGI
Sequence: MSLTTPDKAQVLADALPWLTALNGKIVVVKYGGNAMTDDRLKAAFAADMVFLRNCGIHPVVVHGGGPQISAMLKKLGIAGDFKGGFRVTTPEVLEVARMVLFGQVGRELVNLINAYGPYAVGITGEDAHLFTAVRRTVMVDGVATDIGLVGDVERVNTDAVLDLIDAGRIPVVSTIAPDTAGLVYNINADTAAAALAEALGAEKLLMLTDVEGLYTDWPDRGSLVNQINSDALAELLPTLEEGMVPKIEACLRAIDGGVPSAHVIDGRVEHCVLVELFTNEGAGTKVVRS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECH1_PONAB
Sequence: MAAGIVASRRLRDLLTRRLTASNYPGLSISLRLTGSPAQEEASGVALGEAPDHSYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGVDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIEKCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQDLMKSVQAATENKELKSVTFSKL
What is the function of this protein?
Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA.
What are the official names of this protein?
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion. Peroxisome.
Protein: P2C14_ARATH
Sequence: MTNKLRSEETITSLSSFMASTLSIASPSPCSIPLSVTKVSPLKRKRPTHLNIPDLNPQQPISTDYFRFREGDAKVSPLKRKRPAHLNIPDLNPQQPIRTDYFSFTDFAHQNGTVSFGGNGFGVVSRNGKKKFMEDTHRIVPCLVGNSKKSFFGVYDGHGGAKAAEFVAENLHKYVVEMMENCKGKEEKVEAFKAAFLRTDRDFLEKGVVSGACCVTAVIQDQEMIVSNLGDCRAVLCRAGVAEALTDDHKPGRDDEKERIESQGGYVDNHQGAWRVQGILAVSRSIGDAHLKKWVVAEPETRVLELEQDMEFLVLASDGLWDVVSNQEAVYTVLHVLAQRKTPKESEEENLVQGFVNMSPSSKLRRASLVKSPRCAKSQSYYYNSENESPSLNREIGSSPSKSPITPWKSLWAKAACKELANLAAKRGSMDDITVVIIDLNHYKG
What are the official names of this protein?
Probable protein phosphatase 2C 14, AtPP2C14, Protein phosphatase AP2C4.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: VPE2_PHAVU
Sequence: MAVHRSLLNKPTWCRVAFWWWMLVMVMRIQGTNGKEQDSVIKLPTQEVDAESDEVGTRWAVLVAGSNGYGNYRHQADVCHAYQLLIKGGVKEENIVVFMYDDIATHELNPRPGVIINNPQGPDVYAGVPKDYTGESVTSHNFFAVLLGDKSKVKGGSGKVINSKPEDRIFVYYSDHGGPGVLGMPNMPYLYAMDFIDVLKKKHASGGYKEMVIYVEACESGSIFEGIMPKDLNIYVTTASNAQENSWGTYCPGMYPPPPPEYITCLGDLYSVAWMEDSESHNLKKESVEQQYQSVKQRTSNFEAYAMGSHVMQYGDANMTAEKLYLYHGFDPATVNFPPHNGRLKSKMEVVNQRDAELLFMWQVYQRSNHLPEKKTDILKQIEEIVKHRKHLDGSVELIGVLLYGPEKASSVLRSVRTTGLPLVDDWTCLKSMVRVYETHCGSLTQYGMKHMRAFANICNSGVSETSMEKACVAACGGYHAGLLHPSNTGYSA
What is the function of this protein?
Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms.
What are the official names of this protein?
Vacuolar-processing enzyme, Pv-VPE.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
Protein: TATR_NPVCF
Sequence: MPKNMAALQQSLYTGPSTPSHTQFSRSTEFPENLNFDVLNDSYETFSSVSLTTAEQDNQIDKILQESAAMNRDVNSELAQFTASEYVTGFRADTMEPEVIVETIGDSMKRKASELDSDSDSGESSKGKKRVIKPKMRQRYKKATIQNKTSLTEECNYNTEICTVAPTDQIAEYFKHDFSVYLEKQKSDCQMSANRFSDYISETGYYVFVVKKSEHKPFEVVFAKFVNNVTNEYTNNYYMVDNRVFVVSLNNVKFMVSYKLVREQGIDIPPHVNLCDDAQAERNPYDCYFEPVKNVFQTTLINHFHLDMYYSQTTFVTLMQSMGESKSGMLLNKLYQMFQDRSLFTLPIMLSRKEPTIENTPLSRNYTSSYVAQIIKYSKNVRFPENNPDNGVISRLEEIVTQKSSLTYKYSSVANLLFSRYGHQRDNNADSLKKVKKEDGNRLLVEQYMSQNENDETSHNFIVLQFGGVNDERLTIAKKGIEFFWIAAEIKDINVDDLVKKYTRNVHHVFRIINVNRRESTTWHNNLLKLLQLLLQNLIRIDDVQQYSNKGDSKFIYKRL
What is the function of this protein?
Regulatory transcriptional protein, which trans-activates gene expression from early baculovirus promoters.  Can also trans-activate its own promoter, suggesting that it is autoregulated during normal infection of insect cells.
What are the official names of this protein?
Trans-activating transcriptional regulatory protein, Immediate early protein 1, IE-1.
What is the protein family that this protein belongs to?
Belongs to the nucleopolyhedrovirus IE-1 protein family.
Protein: NP_ADE02
Sequence: MSILISPSNNTGWGLRFPSKMFGGAKKRSDQHPVRVRGHYRAPWGAHKRGRTGRTTVDDAIDAVVEEARNYTPTPPPVSTVDAAIQTVVRGARRYAKMKRRRRRVARRHRRRPGTAAQRAAAALLNRARRTGRRAAMRAARRLAAGIVTVPPRSRRRAAAAAAAAISAMTQGRRGNVYWVRDSVSGLRVPVRTRPPRN
What is the function of this protein?
Plays a role in the inhibition of host immune response within the nucleus.  Interacts with cellular nucleosomes and immobilizes the host immune danger signal HMGB1 on chromatin.  In turn, prevents HMGB1 release out of the cell and thus decreases inflammation.  Also plays a role in the wrapping and condensation of the viral DNA.  May also promote viral genome import into the nucleus.
What are the official names of this protein?
Pre-histone-like nucleoprotein, Pre-core protein VII, pVII.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae histone-like nucleoprotein family.
What are the subcellular locations of this protein?
[Histone-like nucleoprotein]: Virion. Note=Located inside the capsid in association with the viral DNA (core). Present in about 1070 copies per virion. SUBCELLULAR LOCATION: [Pre-histone-like nucleoprotein]: Host nucleus, host nucleolus.
Protein: DAPF_HAEIG
Sequence: MQFSKMHGLGNDFVVVDGVTQNVFFTPETIRRLANRHCGIGFDQLLIVEAPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVTLKGLTNKKDISVSTQKGNMVLTVKDDNQIRVNMGEPIWEPAKIPFTANKFEKNYILRTDIQTVLCGAVSMGNPHCVVQVDDIQTANVEQLGPLLESHERFPERVNAGFMQIINKEHIKLRVYERGAGETQACGSGACAAVAVGIMQGLLNNNVQVDLSGGSLMIEWNGVGHPLYMTGEATHIYDGFITL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDI_CASDE
Sequence: MRFTLKTTAIVSAAALLAGFGPPPRAAELPPGRLATTEDYFAQQAKQAVTPDVMAQLAYMNYIDFISPFYSRGCSFEAWELKHTPQRVIKYSIAFYAYGLASVALIDPKLRALAGHDLDIAVSKMKCKRVWGDWEEDGFGTDPIEKENIMYKGHLNLMYGLYQLVTGSRRYEAEHAHLTRIIHDEIAANPFAGIVCEPDNYFVQCNSVAYLSLWVYDRLHGTDYRAATRAWLDFIQKDLIDPERGAFYLSYHPESGAVKPWISAYTTAWTLAMVHGMDPAFSERYYPRFKQTFVEVYDEGRKARVRETAGTDDADGGVGLASAFTLLLAREMGDQQLFDQLLNHLEPPAKPSIVSASLRYEHPGSLLFDELLFLAKVHAGFGALLRMPPPAAKLAGK
What is the function of this protein?
Anaerobically catalyzes the stereospecific hydration of beta-myrcene to (3S)-linalool and the isomerization of (3S)-linalool to geraniol.  Is thus involved in the initial steps of the anaerobic degradation of the monoterpene beta-myrcene.  Also catalyzes the reverse reactions, i. e.  the isomerization of geraniol to linalool and the dehydration of linalool to myrcene.  In this direction, the formation of myrcene from geraniol may be seen as a detoxification process for the monoterpene alcohol.  Neither the monoterpenes alpha- and beta-ocimene nor the monoterpenoids citronellol and nerol can be used as substrates.
What are the official names of this protein?
Linalool dehydratase/isomerase, Geraniol isomerase, Linalool dehydratase-isomerase, Myrcene hydratase.
What are the subcellular locations of this protein?
Periplasm.
Protein: ACCD_YERPG
Sequence: MSWIERILNKSNITQTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARARLHMLLDAGSEVELGSELEPKDILKFRDSKKYKDRISAAQKDTGEKDALVAMKGTLQGMPIVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLVCFSSSGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPVMRQTLASILSKLTHQPQPSVVESKADTVAQPENQADV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_SYNE7
Sequence: MAVDTANEVKAIARYIRMSPSKVRRVLDQLRGRSYREALILLEFMPYKSCEPILKVLRSAVANAEHNQGLDPTQLVISQAYADMGPSLKRFRPRAQGRAYQIRKQTCHITIAVAPQV
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: P8_RDVS
Sequence: MSRQMWLDTSALLEAISEYVVRCNGDTFSGLTTGDFNALSNMFTQLSVSSAGYVSDPRVPLQTMSNMFVSFITSTDRCGYMLRKTWFNSDTKPTVSDDFITTYIRPRLQVPMSDTVRQLNNLSLQPSAKPKLYERQNAIMKGLDIPYSEPIEPCKLFRSVAGQTGNIPMMGILATPPAAQQQPFFVAERRRILFGIRSNAAIPAGAYQFVVPAWASVLSVTGAYVYFTNSFFGTTIAGVTATATAADAATTFTVPTDANNLPVQTDSRLSFSLGGGNINLELGVAKTGFCVAIEGEFTILANRSQAYYTLNSITQTPTSIDDFDVSDFLTTFLSQLRACGQYEIFSDAMDQLTNSLITNYMDPPAIPAGLAFTSPWFRFSERARTILALQNVDLNIRKLIVRHLWVITSLIAVFGRYYRPN
What is the function of this protein?
Capsid protein which self-assembles to form the outer icosahedral capsid with a T=13 symmetry, about 70 nm in diameter and consisting of 780 molecules capsid proteins.
What are the official names of this protein?
Outer capsid protein P8, Structural protein P8.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus outer capsid protein P8 family.
What are the subcellular locations of this protein?
[Outer capsid protein P8]: Virion. Host cytoplasm. Note=Found in the peripheral regions of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: Y1047_XYLFA
Sequence: MGDFFASIWWMIVSFSVLVTFHEFGHYWVARRCGVKVLRFSIGFGTPLWSRRSSSGTEFVIGAIPLGGYVKMLDEREADVTVAERNQAFNRKSVWQRIAIVAAGPLANLLLCMLLLWVLFVIGKQDYSATVGRAEHLAAQAGIHPGDRITAIDGRQVTSWSEASMLLTAAAMDRQNAVLRVIGPYGERSEHTLELSKLKQPFDERHVTALVGINWQFMLQPPIIAKIEPGSIAEGAIKPGDIVLAVDGQQTLSTEDLYNQIQKLGRDGHPGMIEIRRGEERLALELSPRKSAQGVWLLGVKTNPGPVPAFDSQQRYGVLAAVPLAIRETGRMTADSLGMMKRIITGQASAKNISGPISIAKIANASAKRGVGWFIYFLSLLSLSLAIINLFPIPILDGGHLLYYAIELLKGSPLSTRAMAAGQYIGLALLAGLMGLAFYNDLLG
What are the official names of this protein?
Putative zinc metalloprotease XF_1047.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y448_NOSP7
Sequence: MTGKGQGFGFGLGKMKELADAFKKAQQVQEGAKRLQEELEQMEILGESGGGLVKVIVSGNQEPKRVEISPDALAEGAEVLSDLVTVAMKEAYNKSTATMRERMEELTSGLELPGF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Npun_F0448.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MCA_MYCS2
Sequence: MSELRLMAVHAHPDDESSKGAATTARYAAEGARVMVVTLTGGERGDILNPAMDLPEVHGRIAEVRRDEMAKAAEILGVEHHWLGFVDSGLPEGDPLPPLPDGCFALVPLEEPVKRLVRVIREFRPHVMTTYDENGGYPHPDHIRCHQVSVAAYEAAADHLLYPDAGEPWAVQKLYYNHGFLRQRMQLLQEEFAKNGQEGPFAKWLEHWDPDNDVFANRVTTRVHCAEYFHQRDDALRAHATQIDPKGDFFHAPIEWQQRLWPTEEFELARARVPVTLPEDDLFKGVEP
What is the function of this protein?
A mycothiol (MSH, N-acetyl-cysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate and the MSH precursor.  Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.  Activity is specific for the mycothiol moiety.
What are the official names of this protein?
Mycothiol S-conjugate amidase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family. Mca subfamily.
Protein: CPXP_BRADU
Sequence: MSEQQPLPTLPMWRVDHIEPSPEMLALRANGPIHRVRFPSGHEGWWVTGYDEAKAVLSDAAFRPAGMPPAAFTPDSVILGSPGWLVSHEGREHARLRAIVAPAFSDRRVKLLVQQVEAIAAHLFETLAAQPQPADLRRHLSFPLPAMVISALMGVLYEDHAFFAGLSDEVMTHQHESGPRSASRLAWEELRAYIRGKMRDKRQDPDDNLLTDLLAAVDQGKASEEEAVGLAAGMLVAGHESTVAQIEFGLLAMFRHPQQRERLVGDPSLVDKAVEEILRMYPPGAGWDGIMRYPRTDVTIAGEHIPAESKVLVGLPATSFDPHHFDDPEIFDIERQEKPHLAFSYGPHACIGVALARLELKVVFGSIFQRLPALRLAVAPEQLKLRKEIITGGFEQFPVLW
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 BJ-1, Cytochrome P450 112.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: DCD_ACIF2
Sequence: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: DAPF_SHESA
Sequence: MIQFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGGEVENCGNGARCFARFVRNKGLTNKNKIRVSTSAGKMTLRLERDGTVTVNMGVPVLDPSQIPFKAKKAEKTYLLQTPQQTFLCGAASMGNPHCVLDVEDVANANVAEIGALLTKHERFPRGVNVGFMQVVNSGHIKLRVYERGAAETLACGTGACAAVVVGQIQGKLDQQVRVDLPGGTLTINWEGEGKPLWMTGPAQHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF6_METAR
Sequence: MIRQIDFYGYPYVGIYAANTEQVVVLPPDLPQATVDLVAETLGTAVVRTLINESTLIGSMMTGNSNGFIVSDLTLDREANLLQEHGKVTRLKGKMTAAGNLILANDTAALVHPALTDKNIEAIEKTLKVEVRRGTIGGLKTVGMAGCATNKGILVHPRATEEELTVLEDLFKLPVDIGTVSFGSPLVGSAILATTKGLITGTRTSGPELGRIEDALGFIEE
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: Y1993_ARCFU
Sequence: MLKKLIMGFFLLILLGIAGVAVMNYYYEANYDKELVAYDEGVFNDRVHFTSELLGPGTYRIIAGGTGIVEDIEIIDRSGNVVAKHEDTTNLLYGSSNSFVVRVNYAPPNPGEEYEATIEIYRYVEK
What are the official names of this protein?
Uncharacterized protein AF_1993.
Protein: HIS4_STRGG
Sequence: MPKLELLPAVDVRDGQAVRLVHGESGSETSYGSPLEAALAWQSAGAEWLHLVDLDAAFGTGDNRALIAEVAGAMDIKVELSGGIRDDASLAAALATGCRRVNLGTAALETPEWVAKVIAEHGDKIAVGLDVRGTTLRGRGWTRDGGDLYETLARLDSEGCARYVVTDIAKDGTLEGPNLGLLRDVCAATDRPVVASGGVSSLDDLRAISLLVPEGVEGAIVGKALYAKAFTLEEALKAVAA
What is the function of this protein?
Involved in both the histidine and tryptophan biosynthetic pathways.
What are the official names of this protein?
Phosphoribosyl isomerase A, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, N-(5'-phosphoribosyl)anthranilate isomerase, PRAI, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_RALSO
Sequence: MTRSAKKGPFIDAHLLKKVEAAAGGKDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYVTENMVGHKLGEFALTRTFKGHAADKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: EFTS_PSEAE
Sequence: MAEITAAMVKELRERTGLGMMECKKALTAAGGDIEKAIDDMRAAGAIKAAKKAGNIAAEGSIAVKIAADNKAAVIIEVNSQTDFLALQDDFKGFVAESLEKAFNEKLTDAAPLVEAREEARLALVAKTGENVNIRRLTRVEGDVVGAYLHGHRIGVVVNLKGGNPELAKDIAMHVAASNPQFLSASEVSEEAIAKEKEIFLALNADKIAGKPENIVENMVKGRISKFLAEASLVEQPFVKNPEVKVGDLAKQAGAEIVSFVRYEVGEGIEKAEVDFAAEVAAQVAATKQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_BURM9
Sequence: MAKTATPGACASDPGSGPLPENYEMALAELEALVARMEGGTLSLEDSLAAYRRGAALVAFCQQQLEKAEQQVRVLDGASLKPLSAGTAAADGEDDDL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_ROTH7
Sequence: MGKYNLILSEYLSFIYNSQSAVQIPIYYSSNSELESRCVEFHSKCLENSKNGLSLKKLFIEYNDVIENATLLSILSYSYDKYNAVERKLVKYARGKPLEADLTVNELDYENNKITSELFPTAEEYTDSLMDPAILTSLSSNLNAVMFWLEKHENDTAEKLKIYKRRLDLFTIVASTVNKYGVPRHNAKYRYEYDVMKDKPYYLVTWANSSIEMLMSVFSHEDYLIARELIVLSYSNRSTLAKLVSSPMSILVALVDINGTFITNEELELEFSNKYVRAIVPDQTFDELKQMLDNMRKAGLVDIPKMIQDWLTDCSIEKFPLMAKIYSWSFHVGFRKQKMLDAALDQLKTEYTEDVDDEMYREYTMLIRDEVVKMLEESVKHDDHLLQDSELARLLSMSSASNGESRQLKFGRKTIFSTKKNMHVMDDMANGRYTPGIIPLVNVDKPIPLGRRDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAKHTREYAEFYSQSNQLLSYGDVTRFLSNNAMVLYTDVSQWDSSQHNTQPFRKGIIMGLDILANMTNDARVIQTLNLYKQTQINLMDSYVQIPDGNVIKKIQYGAVASGEKQTKAANSIANLALIKTVLSRISNKYSFATKIIRVDGDDNYAVLQFNTEVTKQMVQNVSNDVRETYARMNAKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKRGQSTQWDQAAVLYSNYIVNRLRGFETDREFIMTKIMQMTSVAITGSLRLFPSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQRAFMSLSSQRSGIADEIAASTTFKNYVSKLSEQLLFSKNNIVSRGIALTEKAKLNSYAPISLEKRRAQISALLAMLQKPVTFRSSKITINDILRDIKPFFTISEAHLPIQYQKFMPTLPENVQYIIQCIGSRTYQIEDDGSKSAISRLISKYSVYKPSIEELYKVISLHENEIQLYLISLGIPKIDADTYVGSKIYSQDKYRILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEIINYAIKNGSWISLFCNYPKSEMIKLWKKMWNITSLRSPYTNANFFQD
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with VP3 capping enzyme, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core.  Following infection, the outermost layer of the virus is lost, leaving a double-layered particle (DLP) made up of the core and VP6 shell.  VP1 then catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded through the DLP's channels into the cytoplasm where they function as mRNAs for translation of viral proteins.  One copy of each of the viral (+)RNAs is also recruited during core assembly, together with newly synthesized polymerase complexes and VP2.  The polymerase of these novo-formed particles catalyzes the synthesis of complementary minus-strands leading to dsRNA formation.  To do so, the polymerase specifically recognizes and binds 4 bases 5'-UGUG-3' in the conserved 3'-sequence of plus-strand RNA templates.  VP2 presumably activates the autoinhibited VP1-RNA complex to coordinate packaging and genome replication.  Once dsRNA synthesis is complete, the polymerase switches to the transcriptional mode, thus providing secondary transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, Protein VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging (By similarity).
Protein: ATG16_YARLI
Sequence: MQLNVTHRTNAERLEKHNRELETALAKKTEEHKEQAKALLLLQDDMLANQIQLNVLEQKTEALQQENETLVQRLVAKAAADADKMNDANAFLER
What is the function of this protein?
Stabilizes the ATG5-ATG12 conjugate which is necessary for autophagy.  The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS).  Recruits also ATG3 to the PAS.  Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).
What are the official names of this protein?
Autophagy protein 16.
What is the protein family that this protein belongs to?
Belongs to the ATG16 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: ACDSB_PONAB
Sequence: MEGLAVRLLRGSRLLRRNFPTCLSSWKIPPHVSKSSQSEALLNITNNGIHFAPLQTFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTGASFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKGTYLPQLTTEKVGSFCLSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDPTIGYKGITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPETNILGQIGHGYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTYNAARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIGTIYEGASNIQLNTIAKHIDAEY
What is the function of this protein?
Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA.  Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA (By similarity).  Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway (By similarity).  Can also act on valproyl-CoA, a metabolite of the valproic acid drug (By similarity).
What are the official names of this protein?
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, SBCAD, 2-methyl branched chain acyl-CoA dehydrogenase, 2-MEBCAD, 2-methylbutyryl-coenzyme A dehydrogenase, 2-methylbutyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CLRN2_HUMAN
Sequence: MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY
What is the function of this protein?
Plays a key role to hearing function.  Required for normal organization and maintenance of the stereocilia bundle and for mechano-electrical transduction.
What are the official names of this protein?
Clarin-2.
What is the protein family that this protein belongs to?
Belongs to the clarin family.
What are the subcellular locations of this protein?
Cell projection, stereocilium membrane; Multi-pass membrane protein.