PharMolix/UniProtQA huggingface dataset:
Protein: Y1486_MYCTU
Sequence: MWCPSVSLSIWANAWLAGKAAPDDVLDALSLWAPTQSVAAYDAVAAGHTGLPWPDVHDAGTVSLLQTLRAAVGRRRLRGTINVVLPVPGDVRGLAAGTQFEHDALAAGEAVIVANPEDPGSAVGLVPEFSYGDVDEAAQSEPLTPELCALSWMVYSLPGAPVLEHYELGDAEYALRSAVRSAAEALSTIGLGSSDVAKPRGLVEQLLESSRQHRVPDHAPSRALRVLENAAHVDAIIAVSAGLSRLPIGTQSLSDAQRATDALRPLTAVVRSARMSAVTAILHSAWPD
What are the official names of this protein?
Uncharacterized protein Rv1486c.
What is the protein family that this protein belongs to?
To M.bovis Mb1522c, M.leprae ML1804 and M.avium MAV321.
Protein: RR4_WHEAT
Sequence: MSRYRGPRLKKIRRLGALPGLTRKTPKSGSNLKKKFNSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKRSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVNIPSFRCKPRDIITTKDNQRSKGLVQNYIASSDPGKLPKHLAIDTLEYKGLVNKILDRKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCS2_PARXL
Sequence: MSLEPFIDSKPFTFGVELEMQIVNTHDYDLTKAGSDLLRLIKDEKIPGNITPEITESMIELSTGICTTHEQAVADLRKIRDTLVSAADHLNVGLCGGGTHAFQQWSERQIVDTPRFQYLSELYGYLAKQFTVFGQHVHIGCPDPNSALYLLHSMSRFIPHFIALSASSPFVQGVDTGFHSARLNSVFAFPLSGRAPFVLTWDSFEEYFSKMVHTGVVNSMKDFYWDIRPKPGFGTIEVRVMDTPLSVDRAAAIACYIQTLARHLLLDKPISPKEDDYLVYTFNRFEACRFGLAGTCINPQTGERKTISEDILETLDRIAPHAEALGSGNALAEIGAIARSQVNDATWLRGVVEREKSLHEAVRQQCLEWRA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: ENGB_PSEA7
Sequence: MSEKNPIVGLCQKASFLISAAQVDQCPPDEGLEVAFAGRSNAGKSSALNTLTHANLARTSKTPGRTQLLNFFSLDESRRLVDLPGYGYAKVPIPLKQHWQRHLEAYLSSRESLAGVFLMMDIRHPLTDFDRLMLDWAQASQLPIHVLMTKADKLAFGAAKNALLKVRREVQQGWGDVASLQLFSAPKRQGVDEAQMVLAQWLGLLDEDEEPVGEA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: AMPH_RAT
Sequence: MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFSIQGAPSDSGPLRIAKTPSPPEEASPLPSPTASPNHTLAPASPAPVRPRSPSQTRKGPPVPPLPKVTPTKELQQENIINFFEDNFVPEINVTTPSQNEVLEVKKEETLLDLDFDPFKPDVTPAGSAAATHSPMSQTLPWDLWTTSTDLVQPASGGSFNDFTQPQDTSLFTMQTDQNMAETEQALPTEPQAEEPPTTAAAPTAGLDLGLEMEEPKEEAAIPPGTDAGETVGTEGSTGEEAEAEKAALPAGEGESPEGAKIDVESTELASSESPQAAELEAGAPQEKVIPSVVIEPASNHEGEEHQETTTGTETREATEDVAPQGPAGEKQELATEPTPLDSQAATPAPAGAVDASLSAGDAAQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRHLE
What is the function of this protein?
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types.  May control the properties of the membrane associated cytoskeleton (By similarity).
What are the official names of this protein?
Amphiphysin.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Protein: SHO1_TRIVH
Sequence: MARFQMSNLVGDPFALATVSIGMLAWIIGVVSCSIAHTKEVVPNFFWWSIAYQLCVLVGVAVVMGSNTSHIYGTAVVGYAAAGLVCTTFTLDSLVTSKQGARQSAGAGLILLAMTDIVWIFYFGSTSQSGPRAYIDSFAPHKEQPHSYRNSKPISHSYTPRPETTVSSAHPHMYSSAPLSGFETSSPMTGFNPAAASTTGLQPVLGSQTNASTVGGETGEVGQPTEYPYRAKAIYSYEANPDDANEISFTKHEILEVSDVSGRWWQAKKSTGETGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENO_NEIMF
Sequence: MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALIGIDASEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAAEDAGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFALDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLVNEFPIISIEDGMDENDWEGWKLLTEKLGGKVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPGKAAFYQLGK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: LPRE_MYCTU
Sequence: MPGVWSPPCPTTPRVGVVAALVAATLTGCGSGDSTVAKTPEATPSLSTAHPAPPSSEPSPPSATAAPPSNHSAAPVDPCAVNLASPTIAKVVSELPRDPRSEQPWNPEPLAGNYNECAQLSAVVIKANTNAGNPTTRAVMFHLGKYIPQGVPDTYGFTGIDTSQCTGDTVALTYASGIGLNNVVKFRWNGGGVELIGNTTGG
What are the official names of this protein?
Putative lipoprotein LprE.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MOAC_ECOLI
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: GLYA_ANAPZ
Sequence: MVGYIGDIHISESDAEVAECLSAEYKRQNTSLQMIASENFVSRAVLQAQGSVLTNKYAEGYPGSRYYCGCSEVDVAETLAVERLCKLFGCKYANVQPHSGSQANQQVYMALLKPGDTVLGMSLDSGGHLTHGAGPNVSGKWFNAVPYNVRRDTNLLDMGEIEEIALRVKPNLIIAGASSYPRRIDFKAFRAIADKVGAYFLADIAHYSGLIAGGQYPTPFGYAHVVTSTTHKTLRGPRGGVIMTDDEEIHKKLRSAVFPGMQGGALMHVIAAKAVAFREAMSPDFKVYVSQILDNSRALAAVLATGGLDVVTGGTDSHMVVVDLRSKGLTGRDVSSSLERAGIVCNKNAVPFDTEKPWVTSGIRLGAAAETSRGLVVKDFEKIGQLVLKIVDSMRAGADMSVVESGVREEVATLVRVVPYDTLAC
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_SALG2
Sequence: MGSNYIVIEGLEGAGKTTARDVVVETLEQLGIRNMIFTREPGGTQLAEKLRSLVLDIRSVGDEVITDKAEVLMFYAARVQLVETVIKPALAQGIWVIGDRHDLSTQAYQGGGRGIDQTMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGDLDRIEQESFDFFNRTRARYLELAAQDSRIRTIDATQPLDAVMRDIRATVTKWVQEQAA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PEX19_CAEEL
Sequence: MTDETTQNIKDKTEEELAALLDQTLGEFTATPAPKPRTTDDELDELMASADQEAAQKAAKDFQKMLEQMVTLQEEAMKKAGADPSEGEGEQPLDPNDPEALAMMDALKQLMECSSNVANASNPEEFMAGLDMLRSPNSPMEPFMSMIMQTLASKEVMYPPLKEIFDNYPKYLEDNGAGLDAETKERYEKQFEVLGKICTEFEKQPELAEVQPVDAATQPAPEADPASIEHFEKLGKLLVELQQYGYPPKELVGALPDGWQIDESGLPKVADAAAATEACSIM
What are the official names of this protein?
Putative peroxisomal biogenesis factor 19, Peroxin-19.
What is the protein family that this protein belongs to?
Belongs to the peroxin-19 family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RGS6_CAEEL
Sequence: MSTPCSGNEPATPTNTSPNNETSNSCLSMGVGVASNETNSSRELKIFKKVIRDPVLRAPFQEFLEQQFCAENLNFYLAVEQFKEIQDFQERSSFGRRIFDRYFAMNSTEPVNIDNSTSKRIRETVESGGFPLDTYDVAQYQILHLLKYDCWPRFLRSTNNSQPSFTDEELAADDEDKNGHSQPTSLNNTNEFEAAAQQSQPAPNAPAATKEKPSKQYSMPAEMTSPVKKNSLSPTHLRRCRPVEPKHCQLMIGDQFNTETVTLSDPTMSVRRWTQEMADAQGMDRMHVEVVDAETGSTIDPARQAIDALQSRALRLVPVVSFIIEFLPANFSFKNPASTPTKLVCIRARHSLSTGAVLRPLLHKYTLDPQVTRIVLNGSLEQVKRSCAVGQVSQKCLTVMSEAQYSDRVNAGKVSLPPRDPILSQLPSTIYEQNNFPFHQNGDISYCEIPNESERNKHAHLQHDGPNAAHQQKEYTLSIFNKFVRKASHAVSKSDPNPSAGTSQDRMASGVYSPATGGPSFASRAAAGTNFGGSANQVNAGSASTSSNNVSEPSKNRLSIFKSKTEKKVVKPESEKEKLKPRSDDIPTTSTSTPMAVETKPNGSRTTEEPLKRMGKSGDDGSQEPQGIRHPAIFSTKIGDEAAAAAAGASPSTSAPSTSTSVQTKTTTSPTKSPTSTTITTSGTTTSATSSVATAPPPVLHAMRSASTPATSSQLTGGGGGNPRESSWQTAAYV
What are the official names of this protein?
Regulator of G-protein signaling rgs-6.
Protein: EFG1P_YARLI
Sequence: MAPPTQRRYTNNRKRRGPREVGGAKTGDGLTRIMKRIRDLERVLKRPVPMDEQKRIELERAVAAYKVQAEDIIGDRKNKKNVEKYRMIRFFERQKASRKVKQARKLVEQADSDAKKKDAEALVVKYMADLAYTIHFPNDIKYISLYPNGAVDETAESSKQREKMRAEFAEQIKNGELDVDLERAEQVATTKKSKKKREAGADEEVKGDDEDDEFLEKAPKKAKVEEEESDDDEEDEEDDDDDDDSDDDDSDDSGEPQMEIKRTADEKQTKEEESDSEEFVDESEAESEGKPESEENSEDQDDESE
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CNEP1_CAEEL
Sequence: MTTIAQSVFCFLAGFFNFFLLYFRKTSRAYCKYQVVKYHSNIPMSPLTTHRLLTVKRKILVLDLDETLIHSHHDGVLRQTVKPGTPSDFTIRVVIDRHPVKFSVHERPHVDYFLSVVSQWYELVVFTASMEVYGTSVADRLDRGRGILKRRYFRQHCTMEVGGYTKDLSAIHPDLSSICILDNSPGAYRKFPHNAIPIPSWFSDPNDTCLLNLLPFLDALRFTSDVRSVLSRNMQALPETQSVQYY
What is the function of this protein?
Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases (PubMed:22134922).  Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (PubMed:22134922).  May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics (PubMed:22134922, PubMed:35852146).  Contributes to closure of nuclear envelope (NE) holes and prevents excess nuclear membranes after meiosis and mitosis, possibly through spatial regulation of lipin (PubMed:32271860).  May limit the production of endoplasmic reticulum (ER) sheets proximal to the NE to prevent the ER membranes that feed into NE openings from invading the nuclear interior and thereby restrict nuclear transport to nuclear pore complexes (NPCs) (PubMed:32271860).  May also indirectly regulate the production of lipid droplets and triacylglycerol (PubMed:22134922).
What are the official names of this protein?
CTD nuclear envelope phosphatase 1 homolog, CTDNEP1, Serine/threonine-protein phosphatase dullard homolog, Small C-terminal domain phosphatase-like phosphatase 21.
What is the protein family that this protein belongs to?
Belongs to the dullard family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus envelope.
Protein: SDHF2_DROVI
Sequence: MLRQLLATARRLLLPLATPKRCLSSKPNGLDKSEYSTPPEVIDYEDPEGLPVPEYPVRPDEPLATRKQRLLYQSRKRGMLENDLLLSTFVAKYLKDFDEDETALYDKLINGVSNDWDIYYWATETKPTPPEYDTDIMKLLKQHVKNTERVQRIRQPDL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CCMH_PSEAE
Sequence: MKRFLATALLGLALCGVARAAIDTYEFASDAERERFRNLTQELRCPKCQNQDIADSNAPIAADLRKQIYGQLQQGKSDGEIVDYMVARYGDFVRYKPPVNERTWLLWFGPGALLLFGVLVIGVIVLRRRRTAAKVQTTLSAEEQARLANLLKNDK
What is the function of this protein?
Required for the biogenesis of c-type cytochromes.  Possible subunit of a heme lyase (By similarity).
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmH.
What is the protein family that this protein belongs to?
Belongs to the CcmH/CycL/Ccl2/NrfF family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein; Periplasmic side.
Protein: RSSA_BRUMA
Sequence: MSAGLETFALKEEDAIKLLACQTHVGAANCDFQMEQYVWKRRADGIHIIHLRKTWEKLLLAARAIAAIDNPGDVCVVSARPYAQRALLKFAAHTGSTPIFGRFTPGCLTNQIQKQFKEPRLLIVSDPRVDHQAVTEASYVGVPVISFCNTDSPLKFIDIAIPCNNKGVQSIGLMWWLLAREVLLIKGKMTRQTGFVLDDKEIMPDLYFYRNPEEQEKEELAEPREVKEPWPGVPPPEVAKIDEVVRSIGMYQTIGGVEPAKKLDFSMVEPVSDWAQETERAVQLDAAQQQEWGASTQNSNW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOE_STAA3
Sequence: MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: PEX6_ARTOA
Sequence: MPITHVALSPSPIPAPTSCASPWIVIPTTIPPLNSSQFPTIPLSTILLPASGAPHPLWEAFANQPSLRAENGIKFPIQLTATTPIALTSVVVGFFSTGEEGLFDEETIEEMITKGLDDMRVVHTGDIVRVQWMSVLARVRLCEPVDQGVITEDTKVIVVKESRGKKTGEPEDGPLANGIDLNGVDDSDSDEDVLSQGDDDDENNVDLPGVSTFMDIATTLGTPSISTPLRNGPGASISGLSDAPKVVKFTAKPLSQKIPTTLLLPTPPAADDAEARVYVRVNELMGLGCFSGDWIGVASDHGLFGDRLPNGSRAWRPAKVYSLPELYAGKEKVKVLMKGCVYMSPLLHANLGSPSSVVLTKSPFMNPSNIQQGALLSPVTTAPPSSATPQIPPTAKEVTLLRISTPISTDRALQPSLLAGLKTYFETSRKMVKVGDLIPVLIDESLGRNLFSPAALLPPDAENAEEIPGAGDELLYGSHGGAGIGVNNTGKLCAAWFRVGTIAPTDEATNAFSNGMTSQQWGGVAIVDPGSTRMVQAGSERGRIPPTLNSPWEYYLNIVPPPIPNNPPPIHPALELPNNYISPVHRRLRELISAATSLRSIKLGLAPLAVLLTSTQRSIGKRLLAYRAASDVGVHIFHIDAYDIIGEGGQASDVKTEAYLRARSERAASCGIENCVLLISHIEAFTAERMAEALRDIVADMRIVIATTTDVDKVPEPVRNVFTHELEVGAPDEGERTGLLRQITQERGVRLAKEIDLSTIALKTAALVAGDLVDVVERAMTACSERMEGLAAEMEGVTVRDIQLAGGDASCLNKQDFEAAVDAARKNFADSIGAPKIPNVSWDDVGGLANVKSAVMETIQLPLERPELFAKGMKKRSGILFYGPPGTGKTLLAKAIATEFSLNFFSVKGPELLNMYIGESEANVRRVFQRARDARPCVVFFDELDSVAPKRGNQGDSGGVMDRIVSQLLAELDGMSEGKEGSGGVFVIGATNRPDLLDPALLRPGRFDKMLFLGVSDTHHKQLTILEALTRKFTLHNSLSLAKISETLPFTYTGADLYALCSDAMLKAITRQASKVDQKIKEMENPVSTAYFFDYLATPDDVAVAVTEDDFMEAKKELIGSVSQKELEHYDRVRQMFETVDEKKGDATVDKKGKGRAIEIMVDGPGTGGEGAFGDDGDEEGLY
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (By similarity).  Regulates autophagy and biogenesis of peroxisomes and Woronin bodies (PubMed:35323036).  Plays important roles in mycelial growth and development and stress response (PubMed:35323036).  Is also essential for conidiation and fatty acid utilization (PubMed:35323036).  Required for nematode predation via trap formation (PubMed:35323036).
What are the official names of this protein?
Peroxisomal ATPase PEX6, Peroxin-6, Peroxisomal biogenesis factor 6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Shuttles between the cytoplasm and the peroxisomal membrane.
Protein: PDXB_SALG2
Sequence: MKILVDENMPYARELFSRLGEVKAVPGRPIPVEELNHADALMVRSVTKVNESLLSGTPINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSALLMLAERDGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCDPPRAARGDEGDFRTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVDIGTSHIAGYTLEGKARGTTQVFEAYSAFIGREQHVALETLLPAPEFGRITLHGPLDQPTLKRLAHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVMCDDETAAALLCKLGFNAVHHPAH
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR2_ASFWA
Sequence: MEELLIENSQRFTIFPIQHPECWNWYKKLESLTWTAQEVDMCKDIDDWEAMPKPQREFYKQILAFFVVADEIVIENLLTNFMREIKVKEVLYFYTMQAAQECVHSEAYSIQVKTLIPDEKEQQRIFSGIEKHPIIKKMAQWVRQWMDPTKNSLGERLVGFAAVEGILFQNHFVAIQFLKEQNIMPGLVSYNEFISRDEGVHCSFACFLISNYVYNIPEEKIIHKILKEAVELVDEFISYAFDKARGRVPGFSKEMLFQYIRYFTDNLCFMMQCKSIYKVGNPFPQMTKFFLNEVEKTNFFELRPTQYQNCVKDDAFAFKLFLNDDDF
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: PRAF1_CANLF
Sequence: MAAEKDQQKDAEPEGLSATTLLPKLIPSGAGRERLERRRATIRPWSSFVDQRRFSRPRNLGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKFVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVVIGSHAAFHQMEAVDGEELQMEPV
What is the function of this protein?
General Rab protein regulator required for vesicle formation from the Golgi complex.  May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes.  In addition it inhibits the removal of Rab GTPases from the membrane by GDI1.
What are the official names of this protein?
Prenylated Rab acceptor protein 1, PRA1 family protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles.
Protein: Y4360_PSEU2
Sequence: MTDTDIKSHKIEFPCNDYPIKVIGDTSVGFTAAVMEVLEKHATVDLKTLAERQSSNGKYTTVQLHIVATGEDQLRDINSALRATGFVHMVL
What are the official names of this protein?
UPF0250 protein Psyr_4360.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: DH16C_ORYSJ
Sequence: MENYQGQHGYGADRVDVYGNPVAGQYGGGATAPGGGHGVMGMGGHHAGAGGQFQPVKEEHKTGGILHRSGSSSSSSSSEDDGMGGRRKKGIKEKIKEKLPGGNKGNNQQQQQMMGNTGGAYGQQGHAGMTGAGTGTGVHGAEYGNTGEKKGFMDKIKEKLPGQH
What are the official names of this protein?
Dehydrin Rab16C.
What is the protein family that this protein belongs to?
Belongs to the plant dehydrin family.
Protein: GPSB_STRP7
Sequence: MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAALVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQILDNSDF
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: NB1_MYCS2
Sequence: MIDLHPNIAPLAPLLGTWAGPGAGEYPTIQSFEYLEEITFGHVGKPFLTYQQRTKARDDGRPLHAEVGYIRVPAPDRVEWVLAHPTGITEIQEGTLTVGGDRITMDVKATTIGLTASAKNVTALARSFRITGDELTYTLQMGAVGQPLQHHLAATLRRTPA
What is the function of this protein?
Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate.  Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively).  Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
What are the official names of this protein?
Peroxynitrite isomerase 1, Ferric nitrobindin, Nb(III).
What is the protein family that this protein belongs to?
Belongs to the nitrobindin family.
Protein: DEF71_ARATH
Sequence: MAMTQVFVIFILLATSLCNSNALPSSVINGFGYDYCIVECSITFLDDACKPLCIDRGYSDGGCIGLSPHFKCCCKK
What are the official names of this protein?
Defensin-like protein 71, Low-molecular-weight cysteine-rich protein 84, Protein LCR84.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.