PharMolix/UniProtQA huggingface dataset:
Protein: SEC31_ASPFU
Sequence: MVRLREIPRTATFAWSPGAASPLIATGTRAGAVDVDFSNETCLELWDLGLSSQDASQELQPIAKIGTDSGFNDLAWTDYEDNSRGVIAGALENGSLDLWDADKLINGSSDAVISRMTKHSGAIKALQFNPKHSNLLATGGAKGELYISDLNNITNPYRLGSAAARADDIECLDWNKKVAHILVTGSSAGFVTVWDVKTRKESLTLNNMGRKAVSAVAWDPEKPTKLITSTPLESDPLIYVWDLRNSHAPERTLKGHESGVLSLSWCPQDPDLLLSSGKDNRTLCWNPQTGQAYGEFPVVTNWTFQTRWNPHNPNFFATASFDGRISIQTVQNTRTDTARAIADQNQALDGADFFAKAQTQPQVSNFSLPKAPKWLERPCGASFGFGGRVISVSLIEKGKRASKIKITPFEVDETVAKSTETFENALKEGDLRSICETRASQAASDEEKADWKVIEALISENPRKSLIEYLGFQDQDDETADKLAQLGLNKEEDEVNGKSAKESRGSGAKKHKRLQSMFDANPEADNFLSDLAASKGAKTNNPFQIFNGSETEADKGITRALLLGNFEKALDVALKEDRMSDAFMIAICGGQKCIEKAQEHYFSKQTDGPNYIRLLASIVGKNLWDVVHNADLSNWREVMAALCTFADDNEFADLCEALGDRLEEQIRNTKDKSLRKDASFCFLAGSKLEKVVAIWIEELRENEQRSIETATDDTSFSIHVRALQSLIEKVTIFRQVTNFQDTERTKDADWKLSMLYDKYIEYADVVATHGRLQVAQKYLDLVPEKHPEAEIARNRIKLAMRHATPQRSQQTVPTTRTPVNKPLPQASMYPAQPAFSAPAAAPAAATTAPRNPYAPPTAATTQPVNPYTPPSAAATQPQTSNSYAPIGGGGYTPAGYQPPQPPTYGTQPLGGSVPPPPRASNQSPATVTTYTTATNLPAWNDLPEGFTKPPTSRRGTSATAAATISSPFPNQSPTLSQGPPPPGAPPTQRAPSVPPPPKGTAPPPRVTSPPTNPPGPSSAANPYASLPQSPPMGSTMGVPPPPSIPRGPSPYNAPPSMPPPSNRYAPSPATQAASPQLSTRAPVPPPPHAAASPYTSQPGSHPPPANPYAPSTPPPSQLPMQQAPPPQATSSRPSTASSQRKAAPAPPKYPPGDRSHIPADAMPIYEILSADMQRVKSRAPSSFKAQVEDAERRLNILFDHLNNEDLLKPNTVADMAELARAIQARDYETAKTIHIDIMTNRTEECGNWMVGVKRLISMSRATP
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec31.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: URIC_CANLF
Sequence: MAHYHNDYKKNDEVEFVRTGYGKDMVKVLHIQRDGKYHSIKEVATSVQLTLSSKKDYVYGDNSDIIPTDTIKNTVHVLAKFKGIKSIETFAMNICEHFLSSFNHVIRAQVYVEEVPWKRFEKNGVKHVHAFIHNPTGTHFCEVEQMRSGPPVIHSGIKDLKVLKTTQSGFEGFIKDQFTTLPEVKDRCFATKVYCKWRYHQGRDVDFEATWDTVRDIVLEKFAGPYDKGEYSPSVQKTLYDIQVHSLSRVPEMEDMEISLPNIHYFNIDMSKMGLINKEEVLLPLDNPYGRITGTAKRKLASKL
What is the function of this protein?
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
What are the official names of this protein?
Uricase, Urate oxidase.
What is the protein family that this protein belongs to?
Belongs to the uricase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: KAD_THEAB
Sequence: MNMVFLGPPGAGKGTYAKRLIEMLNIPHISTGDMFREAVASKSELGKKVEEILKRGDLVPDDLTNSIVKDRLSKEDCKNGFILDGFPRTVAQAKALDEIMRSLGKDLDYVIYFEVDEEEVVKRISNRRICSNCGKIYNLITLPPKVDGKCDVCGGTLYQREDDKEEVVRKRYRVYMENTYPVIEYYQKSNKLFTVNGALDVDSVIKEVLNIIRR
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHA5_RAT
Sequence: MVQLLAGRWRPTGARRGTRGGLPELSSAAKHEDSLFRDLFEDYERWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKIIRVPSDSLWIPDIVLFDNADGRFEGASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDRTDFFDNGEWEIMSAMGSKGNRTDSCCWYPYITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSHADRYFTQREEAESGAGPKSRNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLFVPVIYKWANIIVPVHIGNTIK
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-5.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: CARA_RUBGI
Sequence: MLPVLPPALLALADGTTFLGTSIGAPGRTVGEVVFNTALTGYQEILTDPSYCRQIVTLTYPHIGNVGVNEEDVEAAKVHAAGLVIKDLPLRVSNFRAAMPLSQYLEREGTVAIAGIDTRRLTRVLRTTGAQNGCIVSFAPGTVVGEAEIAAAVAAAKAAPSMAGLDLAQVVSADAPYEWTETSWQLGRGHGTLADAEFHVVAYDFGVKRNILRLLADRGCRVTVVPARTPAAEVFKLKPDGVFLSNGPGDPEPCDYAIAAAREIIDAGVPTFGICLGHQIMALASGAKTFKMKFGHHGANHPVKDLDSGRVSITSQNHGFAVDEKTLGANLRPTHVSLFDGTLQGLARTDRPAFCFQGHPEASPGPHDIGYLFDRFVALMQERA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RS10_CHRVO
Sequence: MSSQKIRIRLKAFDYNLIDRSAQEIVETAKRTGAVVKGPVPLPTKIERFNVLRSPHVNKTSRDQLEIRTHLRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: FAF2A_XENLA
Sequence: MAALEERELSQEQTEKLLQFQDLTGIESMDQCRQTLQQHNWNIEAAVQDRLNEQEGVPRVFNNPPNRPLQVNTADHRVYSYVVSRPQPRGLLGWGYYLIMLPFRITYYTLLDIFRFTLRFIRPDPRSRVTDPVGDVVSFIHLFEEKYGRIHPVFYQGTYSQALNDAKQELRFLLVYLHGEDHQDSDDFCRNTLCTPEVTHFINSRMLFWACSTNKPEGFRVSQALRENTYPFLGMIMLKDRRMTVVGRLEGLMQPQDLINQLTFIIEANQTYLVSERLEREERNETQVLRQQQDEAYLVSLRADQEKERKKKEKQEQKRREEEEAQRKQMLEERKKRNLEEEKERKSECLPAEPVPDHPDNVKIIFKMPNGTRVERRFLFTQSLSVIHDFLFSLKETPEKFQIVTSFPRRVLPCLPSEEIPVPPTLQEAGLSQSQLLFVQDLTDD
What is the function of this protein?
Plays an important role in endoplasmic reticulum associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Involved in inhibition of lipid droplet degradation.
What are the official names of this protein?
FAS-associated factor 2-A, UBX domain-containing protein 8-A.
What are the subcellular locations of this protein?
Cytoplasm. Lipid droplet. Endoplasmic reticulum.
Protein: PYRG_BACAH
Sequence: MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSSVLQKERRGEYLGGTVQVIPHITNEIKERVYRSGRETNADVVITEIGGTVGDIESLPFLEAIRQIKSDIGRDNVMYIHCTLIPYLKAAGEMKTKPTQHSVKELRSLGIQPNIIVVRTEMPVSQDMKDKLALFCDIDTKAVIEARDADTLYAVPLSLQEQNMDQIVCDHLKLDNPAADMTEWTALVEKVRNLSKKTKIALVGKYVELQDAYISVVEALRHAGYSFDTDVEVKWVNAEHVTAENVQELVGDTDGILVPGGFGDRGVEGKIVAIQYARENKVPFLGICLGMQLASIEFARNVLGLEGANSSEINPDTPYAIIDLLPEQKDVEDLGGTLRLGLYPCKLSEETNAYNAYNEPVVYERHRHRYEFNNQFRPDMEKEGFVFSGTSPDGRLVEIIELKDHPWFVAAQFHPELVSRPNRPQPLFHDFVKASITNKESK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NLTP_CITSI
Sequence: ITXGQVTGSLAPXIAFLRTK
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).
What are the official names of this protein?
Non-specific lipid-transfer protein, LTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: 443R_IIV6
Sequence: MSFNLNNALDDKITVVRGIPGDIVIFGIDGTIADSGVPVSIGSGQAKQPTAVPGDLAVFGSGVNQGQTIDSGLTVDDSSVSLPTVLWSSQKIESLIPTGSFLPLAGGTMTGTIISKDIVVPSGNVITLTDLPTVGTSAANKTYVDSKVSPGGPFLPLTGGTMSGDIVIQTGDIISIADLPITANSAANKAYVDSQISSGVPNATPTVLGKIQLAGDFDVTSTATVPVIKSATTSLEGKIQLAGDFDSSSTASIPIIKSATTLIEGKIQLAGDLTGTATSPLVAPGSITISKMAPLSASSKLIGSSSSTTVAEIGVGGSLEISSGILQENIPSLSNIFLPLSGGTMAGNIIVPTGDYITITDPPTVGTGAANKAYVDANITPNATPTVLGKIQLSGDISGTAIAPVVSPGAITLSKMANLNAVSNLIGSSNTNVTPTNISLGSNLQMTGTTLNVNLTSLSGSFLSLLGGTMSGNIIIPSGDLISIADAPVSGTSAANKSYVDSQIIVNATPNATSTVLGKIQLTGDLLGSSATFPTVAPGAITLSKLANLSSPSKLIGSGSTSSSPANITLGTSLSMSGTSLNVVPTFSNPTFNGTISGTAVLGVSNGGTGNSTLTGYVVGNGTAPFTAVTSIPVSNVNGAVQSVNGVFPDLSGNVTVTLGTVTTGTLAALPPVGPPLVNGDIYVVSGDPTPSNNGLTFIYSTTPTNQWLEISPSFGSLDARYLQLSGGTMSGNIVIPSGNFITLTSLPVNPTDAANKSYVDVNITPSATTSLQGKVQLSGDLSGVASAPVITTGAITLTKMANLTSTSSLIGSSSTSTSPSQLSLGSNLQISGTTLDVNTSSLSGTFLPLTGGTMSGNIVIPTGDLISITDAPTIGTSAANKAYVDANITPNATSTVLGKIQLAGDLLGSSATLPTISAGAVTLSKMANLSTTMSLIGSSSTSNLVSQLSLGSNLQISGTTLDVNTSSLSGTFLPLAGGTMSGNIVIPTGDLISIADAPTVGTSAANKAYVDANITPNATTTVLGKIQLSGDFDSTSTATVPVIKSATSSIQGKIQLSGDLTGSSTSPTIAAGAITLVKMANLSGNSQIIGSSSTASTPTNLTLGSGLQISGTVLSVNSATLTVPPATATTIGGIEMLGDLTGSVATAPTVATGAITLAKMANLSGNSQIIGSSSTTSTPTNLTLGSGLQISGTVLSVNSATLTVPPATSTSLGGIEMLGDLTGSVATAPTVAAGAITLAKMANLSGNSQIIGSSSTASTPVNLTLGNFLQMTGTVLNVNSSSLSGTFLPLSGGTMSGNIVIPTGDLISIADAPTVGTSAANKAYVDAQIISATPNATTTTLGKIQLSGDFDSTSTATVPIIKSATSSIQGKIQLSGDLTGSSISPTVAAGAITLAKMANLSGNSQIIGSSSTTSSPTNLTLGSGLQISGTVLSVNSATLTVPPATATTIGGIEMLGDLTGSVATAPTVAAGAITLAKMANLSGSSQIIGSSSTTSAPTNLTLGSGLQITSTVLSISAATSSTLGGIEMLGDLTGSVATAPTVAAGAITLAKMANLSGNSQIIGSSSTASTPTNLTLGSGLQISGTVLSVNSATLTVPPATATTIGGIEMLGDLTGSVATAPTVAAGAITLAKMANLSGNSQIIGSSSTASTPTNLTLGSGLQISGTVLSVNSATLTVPPATATTIGGIEMLGDLTGSVATAPTVAAGAITLAKMANLSGNSQIIGSSSTASTPTNLTLGSGLQISGTVLSINSATLTVPPATATTIGGIEMLGDLTGSVATAPTVAAGAITLAKMANLSGNSQIIGSSSTASTPTNLTLGSGLQISGTILNVNTTSLSSTFLPLAGGTMSGNIIIPTGDLISIADAPLVGTSGANKSYVDSQIIANATPSATTGIQGKIQLAGDLGGSGTTASSPVISSGAITLTKMANLSGNSQIIGSGSTSSSPVNLTLGSGLQISGTVLSVNSATLTVPPATATTIGGIEMLGDLTGSVATAPTIAAGAITLAKMANLSGNSQIIGSSSTTSTPTNLTLGSGLQISGTVLSVNSATLTVPPATATTIGGIEMLGDLTGSVATAPTVATGAITLSKMANLSGNSQIIGSSSTTSTPTNLTLGSGLQISGTVLSVNSATLTVPPATATTIGGIEMLGDLTGSVATAPTVAAGAITLAKMANLSGTSQLIGSSSTTTSPANISLGSTLQMSGTTLSVNTSTLMLLVPSSVNGDLATLNASGQVIDSGVSINNSGLTSASLWNAAKLAITTNSWFAGTNPNTTAPTDRPATSSVLYVGTDASLWIWNGSVYISLIGAKVPTSVTRTFTTSTGASGFQISTINGAFVHYSVSISTTIGVGGTSTGTVNLEVSPTNSATPASWIVNGVISNSQSFAGLITLSSVQVQGGQLCTYVPAGYFVKLRTTSSGTTSFSYVAGIEVLDN
What are the official names of this protein?
Uncharacterized protein 443R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 261R/396L/443R family.
Protein: EX7S_PSEFS
Sequence: MARKKVALDFEQSLADLQTLVERLENGELSLEDSLTAFEQGIGLTRDCQSALAQAEQKVQVLLERDGELAEEPFDAEQPE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_SALNS
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: VATA_VIGRR
Sequence: MPAVYGARLTTFEDSEKESEYGYVRKVSGPVVVADGMAGAAMYELVRVGRDNLIGEIIRLEGDSATIQVYEETAGLMVNDPVLRTHKPLSVELGPGILGNIFDGIQRPLKTIAKRSGDVYIPRGVSVPALDKDTLWEFQPKKIGEGDLLTGGDLYATVFENTLMQHHIALPPDAMGKITYIAPPGQYSITDTVLELEFQGVKKKFTMLQTWPVRTPRPVASKLAADTPLLTGQRVLDALFPSVLGGTCAIPGAFGCGKTVISQALSKYSNSDAVVYVGCGERGNEMAEVLMDFPQLTMTLPDGREESVMKRTTLVANTSNMPVAAREASIYTGITLAEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLAARLASFYERPGKVKCLGGPERTGSVTIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLISYSKYSTALESFYEQFDPDFINIRTKAREVLQREDDLNEIVQLVGKDALAEGDKITLETAKLLREDYLAQNAFTPYDKFCPFYKSVWMMRNIIHFYNLANQAVERGAGSDGQKITYSLIKHRVGDLFYRLVSQKFEDPAEGEAALVGQFQKLHEDLSTGFRNLEDETR
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, VAA3-1, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: MACD1_MOUSE
Sequence: MSLQSQVSGRLAQLRAAGQLLVSLRPWPGRSAGGPRPRGSACGPLVALGEHGYCAWLSAGVGAWGAAGRGAWVRTWAPLAMAAKVDLSTSTDWKEAKSFLKGLSDKQREEHYFCKDFIKLKKIPTWKETAKGLAVKVEDPKYKKDKQLNEKISLYRGDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGSLLTDECRTLQNCETGKAKITCGYRLPAKYVIHTVGPIAVGQPTASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEVVLASLREWLEQHKDKVDRLIICVFLEKDEGIYRERLPHYFPVA
What is the function of this protein?
Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety.  Inactive towards proteins bearing poly-ADP-ribose.  Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins.  Plays a role in estrogen signaling.  Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen.  May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation.  Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction.  Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells.  Enhances ESR1-mediated transcription activity.
What are the official names of this protein?
ADP-ribose glycohydrolase MACROD1, MACRO domain-containing protein 1, O-acetyl-ADP-ribose deacetylase MACROD1, Protein LRP16, [Protein ADP-ribosylaspartate] hydrolase MACROD1, [Protein ADP-ribosylglutamate] hydrolase MACROD1.
What are the subcellular locations of this protein?
Nucleus. Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins.
Protein: THIQ_HAEIN
Sequence: MIYLNNVILNDKTLPMCFNLSVNAGERVAIIGESGAGKSTLLNLIAGFEFPAQGEIWLNDKNHTRSAPYERPVSMLFQENNLFPHLTVQQNLALGIKPSLKLTALEQEKIEQVACSVGLGDYLERLPNSLSGGQKQRVALARCLLRDKPILLLDEPFSALDQKLRVEMLALIAKLCDEKDLTLLLVTHQPSELIGSIDQVLVVENGQISQLQKGV
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CDD_SALHS
Sequence: MHPRFQTAFAQLADNLQSALAPILADHHFPAMLTAEQVSTLKNTAGLDEDALAFALLPLAAACARTDLSHFNVGAIARGVSGNWYFGANMEFLGATMQQTVHAEQSAISHAWLRGEKGLAAVTVNYTPCGHCRQFMNELNSGLDLRIHLPGRAPHTLRDYLPDAFGPKDLEIKTLLMDEQDHGFTLTGDTLTQAAITAANKSHMPYSHSPSGVALECKDGRIFTGSYAENAAFNPTLPPLQGALNLLSLNGYDYADIQRAILAEKGDAALIQWDATAATLKALGCHNIDRVLLG
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: GPMI_STAEQ
Sequence: MAKQPTALIILDGFANRESEHGNAVKQAHKPNFDRYYEKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGEFFDNTVLNNAVKHVKDNGSALHVFGLLSDGGVHSHYKHLFAILELAKKQGIDKVYVHAFLDGRDVDQKSALKYIEETEDKFKELGVGQFASVSGRYYAMDRDKRWDREERAYNAIRNFEGPTFTSAKAGVEANYKNDVTDEFVEPFIVEGQNDGVNDGDAVIFYNFRPDRAAQLSEIFTNKAFDGFKVEQVDNLFYATFTKYNDNVDAEIVFEKVDLNNTIGEVAQDNGLKQLRIAETEKYPHVTYFMSGGRNEEFEGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELDKGDLDLILLNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKIIDMGGHAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVKQPSEMTGESLIKH
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RL6_BORAP
Sequence: MSRIGRLPIKIPDTVKIDVKDNLVIVEGIRGRLVQNIKDSINVKVENGSVIVGRVFNDKKAKAYHGLYRSLIFNMIKGVTEGFSKSLTINGIGYRAEQQGNSLFLSLGYSTQFEYVIPDGVSVKLDGNTKISVEGIDKFKVGQVAAEIRSLKKPEPYKGKGIKYDNEIIRRKVGKSGVKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PYRB_CLOBH
Sequence: MLKGRNLLDPMDFSLEELEEVFKLADEIIEEPEKFLHVCDGKILATLFYEPSTRTRFSFEAAMLRLGGQVIGFSEPNSSSVAKGESVADTIRTVGCYADIAAMRHPKEGAPAIAAMYSDIPVINAGDGSHQHPTQTLTDLLTIRSLKGDLSNLTIGCCGDLKFGRTVHSLVKALSRYKNNKFVFMSPEELKIPDYIRKEILEKNNIEYKEISKMEDAMAELDILYMTRVQRERFFNEDDYVRLKDSYILDGEKMKYAKKDMMVLHPLPRVNEIAYEIDQDPRGCYFKQAKYGMYVRMALIAKLLGVR
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CAPSD_TYCS1
Sequence: MPKRTGDILISTPVSKVRRKLNFDSPYTSRAAAPTVQGIKRRSWTYRPMYRKPRMYRMYRSPDVPFGCEGPCKVQSYEQRDDVKHTGVVRCVSDVTRGSGITHRVGKRFCIKSIYILGKIWMDENIKKQNHTNQVMFFLVRDRRPYGTSPMDFGQVFNMFDNEPSTATVKNDLRDRYQVMRKFHATVVGGPSGMKEQCLLKRFFKVNTHVVYNHQEQAKYENHTENALLLYMACTHASNPVYATLKIRIYFYDAVTN
What is the function of this protein?
Encapsidates the viral genome into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement.  The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).
Protein: RS7_XANC8
Sequence: MSRKGSTPQRTVLPDPKHGSETIARFINMVMQSGKKSVAEKIVYGAMDVIGEKNPNAVELVQKALDNVAPAVEVKSRRVGGATYQVPVEVRSSRRMALAMRWLIDSARKRGENTMPRKLAAELLDASESRGGAIKKREETHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: OTC_PARMW
Sequence: MATAAAGVAAALSPLSGRDYLSSADCSAEETSAVLDLAAQLKSGDRRIDLGNRVLGLIFTKASTRTRVSFQVAMARLGGQTVDLNPKVTQLGRGEPLEDTARVLSRYCDVLAVRTFAQQELVDYAHWATVPVINALTDLEHPCQSLADFLTMREAHGDLPGQTLAYIGDGNNVAHSLMLCGALLGVNVRIGCPQGFEPLPGVLEQARSLAVQGASIEVIHDPREAVRGAQAVYTDVWASMGQEDEQSEREQAFAGFCVDEALMEAADTEAIVLHCLPAHRGEEISPGVMESSASRIFDQAENRLHAQQALLAALMGGL
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_RICPU
Sequence: MLNIGLSGSTGKMGETILERIDKFKDCKIAAKFNSTNNLDDLDNFCKNSDVIIDFSTPEILEKLINYALKHNTKLVIGTTGLQPQHFKLLEKAAQTLPVLYSANMSIGANLLSYLAKEVTKILDDYDVEILETHHRNKKDSPSGTAVMLAETIASKKGLNITFNRGNRLRSEKEIGISSLRGGNVHSIHEISFLGDDEIITLKHEALNKNSFSIGAIKAAIWLQDKPSALYSMQDIYKI
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_MYCTU
Sequence: MADAARARRLAKRIAAIVASAIEYEIKDPGLAGVTITDAKVTADLHDATVYYTVMGRTLHDEPNCAGAAAALERAKGVLRTKVGAGTGVRFTPTLTFTLDTISDSVHRMDELLARARAADADLARVRVGAKPAGEADPYRDNGSVAQSPAPGGLGIRTSDGPEAVEAPLTCGGDTGDDDRPKE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_PSEFA
Sequence: MTPLETKRPLQLNDQGQLQHFLSLDGLRRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLSADVITLNVSTSSASKGETLLDTLRNLEAMAADMFVVRHGDSGAAHFIAEHVCPQVAIINGGDGRHAHPTQGMLDMLTIRRHKGSFENLSVAIVGDILHSRVARSNMLALKTLGCPDIRVIAPKTLLPIGVEQYGVKVYTDMTEGLKDVDVVIMLRLQRERMTGGLLPSEGEFYRLFGLTTARLAGAKPDAIVMHPGPINRGVEIESAVADGPHSVILNQVTYGIAIRMAVLSMAMSGQTAQRQFDQENAQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.