PharMolix/UniProtQA huggingface dataset:
Protein: CFBD_METBF
Sequence: MAEKEISIIHPRPSSIVAALYTLRDLNVDVAIMHGPPGCSFKHARLLEEDGIHVVTTGLDENNFVFGGHDKLVQLINKSVELFNPKLIGIVGTCPSMIIGEEMHDAVLEANPDVPVIEVEVHAGYHDNTKGVLFALESALDAGIIDHKEFERQKYLLEKATEVEKKFGAASREYLAPSRGDVKYKAAQRVIQLLKEGKKGLVIMNAKKETGYMFADITLAVNEVAEALGNKENLINMANIDPELGLPRVRQHAEYITRDLKAHGVEVHEIIGGMDEYPIAGEKVSELIKEKYSDFDFAVISGVPHAIPMENIKNMELISITNGPRQVLPLKEMGHEYVLVEIDLHPKTLGVSGIVESEFGATLREVAKEA
What is the function of this protein?
Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes both the six-electron reduction of the tetrahydroporphyrin ring system and the gamma-lactamization of the c-acetamide side chain of Ni-sirohydrochlorin a,c-diamide to yield 15,17(3)-seco-F430-17(3)-acid (seco-F430), the last intermediate in the biosynthesis of the coenzyme F430.
What are the official names of this protein?
Ni-sirohydrochlorin a,c-diamide reductive cyclase complex, component CfbD, NifD homolog component CfbD, Nitrogenase-like protein.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: CATD_BOVIN
Sequence: VIRIPLHKFTSIRRTMSEAAGXVXXLIAKGPISKYATGEPAVRQGPIPELLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWTHRKYNSDKSSTYVKNGTTFDIHYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDKNVFSFFLNRDPKAQPGGELMLGGTDSKYYRGSLMFHNVTRQAYWQIHMDQLDVGSSLTVCKGGCEAIVDTGTSLIVGPVEEVRELQKAIGAVPLIQGEYMIPCEKVSSLPEVTVKLGGKDYALSPEDYALKVSQAETTVCLSGFMGMDIPPPGGPLWILGDVFIGRYYTVFDRDQNRVGLAEAARL
What is the function of this protein?
Acid protease active in intracellular protein breakdown.  Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation.
What are the official names of this protein?
Cathepsin D.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Lysosome. Melanosome. Secreted, extracellular space.
Protein: MURA_BUCAP
Sequence: MNKLYIEGDKKLNGNVIISGSKNAALPILFMTILTEKKIKISNVPKLRDINIAIQLLKSLGAQIKYKKKNLYIDTSSIKIHSPPYDLTKQIRASIWMLAPLLIRFGKAKIFLPGGCKIGARPIDLHIKGLIALGAKIILEKNYISASIKKPLTGKRIYIEKISVGATITVMSAATLAQGTTIIENAAQEPEIIDTAKFLNTLGANIIGAGSNRIFIKGVLTLIGGKHKIIPDRIETGTFLIAAAISKGYIICHDTEPKYLKNVLMKLSESGAEIKTGKDWIQLDMRGKKPKSINISTSPYPGFPTDMQPQFALLNSISQSKGTITENIFENRFIYTSELIKMGAKIKIKNNSIVCKGVPNLYSQNVFSNDLRGSATLVLAGCIARGTTTVDNIHHFERGYEAFSEKLNKLGANIKYI
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1221_CLOK1
Sequence: MSKDNTIQFDISESKKALTREILTEVYDSLIKKGYNPVNQLVGYLISGDPTYITNYNGARSLVRKLERDEILEEVLKAYLGIK
What are the official names of this protein?
UPF0297 protein CKR_1221.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: 3L2O1_OXYMI
Sequence: MKTLLLTLVVVTIVCLDLGYTRRCFITPDVRSERCPPGQEVCYTKTWCDGFCGSRGKRVDLGCAATCPTPKKKGIDIICCSKDNCNTFPKWP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 3FTx-Oxy1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7S_BRUSU
Sequence: MTEPSNADIAVMSFEDALKQLEKIVDDLERGDVPLEESIRIYERGEALKKHCDTLLKSAEDKVEKIRIGRDGQPVGTEPLDPE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_ECO27
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_HAEIE
Sequence: MALWGGRFTQAADKRFKDFNDSLRFDYRLAEQDIQGSIGWSKALVKVNVLTIEEQHQLEQALNELLVEVRSNPQAILQDDAEDIHSWVESKLIDKVGNLGKKLHTGRSRNDQVAVDIKLWCKQRVVELQESVRNLQRHLVQTAENTQQAVMPGYTHLQRAQPITFAHWCMAYVEMFDRDYSRLTDAYNRMNTCPLGSGALAGTAYAVDRDSLAHDLGFAFATRNSLDSVSDRDHIVELLSIASLSMAHLSRFAEDMIIFNSGEANFVELSDRVTSGSSLMPQKKNPDACELIRGKTGRVIGSLTSMLITLKGLPLAYNKDMQEDKEGIFDALDTWQNCVDMATFVLDELKVNVERTREAALKGYSNATELADYLVSKGVPFRDSHHIVGETVVYAIEKGKGLEDLTIPEFRQFSEVVGDDVYEILSLQSCLDKRCAKGGVSPLRVAEAIAEAKTRFA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_SALAI
Sequence: MTTATETKTMPRLKERYRNEIVGQLREQYKYGNPMQVPGLVKIVVNMGVGEAARDAKLIDGAVRDLATITGQKPQVRRATKSIAQFKLREGMPIGAKVTLRGDRMWEFLDRLLSIALPRIRDFRGLDGRKLDGNGNYTFGLTEQSVFHEIDQDKIDRQRGMDITVVTTATTDDEGRALLKFLGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DXR_LEPBP
Sequence: MVGVSVLGISGSVGTSTVKVLRQFPDQFDLRSFSVHSNWNVAKALVEEFSPEVICITDPKLVGKFGDSYLSTKILYGDKALIDLVQLPSVGVVVTAVMGARGVLPTIAAIEAGKKIAIANKETLVTFGPLINRLVAKHNTVMVPVDSEHNALFQLIERETRSNIRAITLTASGGSFRTLPLEALEHVSVKQALNHPTWSMGPKITVDSAGLINKGLEVIEAHFLFGFSYDEIEVVIHPQSITHGIIETTDGACLLYASHPDMVYPIAHSLFYPNPTPQMLIERKPSTWNTFEFFPPDTKRYPGLLLAYQAGKAGGAAPGIFNAANEEAVALFLEEKISFTTIPRLIESALNQIENVFPETLDGYLEKDQETRNYIQREFNQGGVTT
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ACCD_PICAB
Sequence: MSIREWFEDRRKITGLLKNSVERDSKDVNEMERNKNLSIDYVKINRLWVQCDNCESLLYIRFLRENKSVCEECGYYLQMNSSDRIELLIDRGTRHPMDEDMYTLDVLQFHSENEPAHSDPLHSEDESYKDHITFCQIETGLTDAIQTGIGQLNGLPIALGVMDFKFMGGSMGSVVGEKITRLIERATEESLPVIMVCASGGARMQEGSFSSMQMAKIASALYIPQKDNRLLYVSILTSPTTGGVTASFGMLGDIIIAEPKAYIAFAGKIVIDQTLGQKVIEDFQVTEHLFGHGLFDLIVPRNLLKCVLSELFYVLQSSS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GL_HCMV7
Sequence: MCRRPDCGFSFSPGPVILLWCCLLLPIVSSAAVSVAPTAAEKVPAECPELTRRCLLGEVFQGDKYESWLRPLVNVTGRDGPLSQLIRYRPVTPEAANSVLLDEAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVLPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA.  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: AROC_ECOLI
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLDIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.  It uses NADPH to reduce FMN.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase, EPSP phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: Y186_STAES
Sequence: MKYYGKCISYISILILTFFIGGCGFMNKENNKEAEIKESFHKTLSMYPIKNLEDLYDKEGYRDEEFEKRDKGTWIINSVMNIQKKGQAMESRGMVLYMNRNTRKTTGHFYTSITTEDKKGRVYNKEKNTLFNLKNNKIEPTKPIVDETLKNEIKNFQFFSQYGNFKNLKDYKNGNVSYNPNVPSYSAEYQLSNEDDNVKQLRKKYDIPTKKAPKLILKGDGDLKGSSIGHKHVELSFVRNKEESIYFSDSVEFNPSEVNNE
What are the official names of this protein?
Uncharacterized lipoprotein SE_0186/SE_0187.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: M2K2_ARATH
Sequence: MKKGGFSNNLKLAIPVAGEQSITKFLTQSGTFKDGDLRVNKDGVRIISQLEPEVLSPIKPADDQLSLSDLDMVKVIGKGSSGVVQLVQHKWTGQFFALKVIQLNIDEAIRKAIAQELKINQSSQCPNLVTSYQSFYDNGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRGEVKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVGNKYGNKSDIWSLGLVVLECATGKFPYAPPNQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFISTCLQKDPNSRSSAKELMEHPFLNKYDYSGINLASYFTDAGSPLATLGNLSGTFSV
What is the function of this protein?
MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity.  Plays a role in abiotic stress tolerance and plant disease resistance through activation of MPK4 and MPK6 by phosphorylation.  Acts redundantly with MKK1.
What are the official names of this protein?
Mitogen-activated protein kinase kinase 2, AtMAP2Kbeta, AtMKK2, MAP kinase kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: Y5075_BACC1
Sequence: MIKPLIEFCVGNLASGSQAALEKLEKDPNLDVMEYGCLGYCGICFEGPFALVNGEVVQGATVEELVNNVYEYLDENPMF
What are the official names of this protein?
UPF0349 protein BCE_5075.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: TSAD_LEPIC
Sequence: MIGMGIETSCDETSIGIVRDGKDLLSLKIFSQIDLHKPYGGIVPEIASRAHLEKINLLLEEAMEESEIQFKDLSYVAVTSSPGLTGSLMVGAQMARCIHMVYETPILPVCHLQSHFAVLHLEGVPTEFPVLGLLLSGGNSAIYILHEFGKMELLGDTMDDALGEAFDKVAGLLELPYPGGPHIEVRAKEYKPSPNEKPILPALLRNLPQEEVSFSFSGLKTAVMVLLEKQKELSKERICWNFQNSAFDLVERNLKRAVSKTGIKRIFAAGGVLANFTLQNRLYTWAEKNSVELFAPKKKIYCTDNGAMVASLGYYLFQKGYQRDIDFTVSPSRQEIFS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_TRIEI
Sequence: MTTAARLGIGGPVGSGKTALLECIVPLLTNQGIEVAIVTNDLLTTEDAERLKSGGILPRDRIIGVETGSCPHTAIREDPTMNILAVQDLEQLFPNLNLIMIESGGDNLASTFSYDLVDAYIFVIDVGAGDDIPRKKGPGFMQADLVVINKIDLAPYVNANLNLIRKEASVYRQSKPIAYTNCKTGVGLNEVVNFILERVLFRTALSVKNLEK
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_CHLPD
Sequence: MASRTEHADLSDLSGDSGFKRIATISLAALGVVFGDIGTSPLYAIRECFHGDYSIPVSQQNVLGVLSLIFWALVLIVSLKYLTFIMKADNEGEGGILALTALIVAHSKKNRHERWFLVGIGLFGASLLYGDGMITPAISVLSAVEGLQIIAPAFKDLVIPITVIILTGLFLYQHNGTARVGALFGPVILLWFAVIGVLGLVEIVRYPEILRAVLPWYGFSFLLNNHLQGFMVLGAVFLSVTGAEALYADMGHFGKTPIRFTWILFVLPALLLNYFGQGALLLFAPQESHHPFYGLVPSWAMIPMVILATSATIIASQALITGVFSLTQQAIQLGYLPRITVKHTSAGHRGQIYVPGANWALMYATIGLVIGFGSSSKLAAAYGVAVTATMLISTILFYYVARDIWRWNKLATNLLVSFFFVIDLAFFGASATKLFHGAWFPLVIGLVLFTLMLTWKQGRSLLLQQIKDRTLTVEEFVQSLALQQPQRVTGQAVYLTANPDVIPIALLHNLRHNKILHSEVALFHFSLERVPRVPNSKKVEIKKYGDGLCRVVARYGFMEYPSIRQVFSLAQEKGLHFRLETTSFFLSREKIVTGLKSKMGLWRKKLFALMVRNALSATSYYDMPSGQVIEIGMQVQI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NS5A_IBVM
Sequence: MKWLTSFVRAVISCYKPLLLTQLRVLDRLILDHGPKHILTCVRCVILFQLDLVYRLAYTPTQSLV
What are the official names of this protein?
Non-structural protein 5a, ns5a, Accessory protein 5a.
Protein: PYCA_ARCFU
Sequence: MFSKILVANRGEIAVRVMRACRELGIKTVGVYSSADKRAFHRVYADECYYIGKADPRDSYLNIDRIIEVAKKSGAEAIHPGYGFLAENAEFAERCEEEGIVFIGPSPEVIRIAGSKVRSRESMQRAGVPVIPGSPKIDTVDEAKEWAEKIGYPVAVKASGGGGGIGIVVVNSQEELEEAFRKSKKLGESYFKDSTVYLEKYLARPRHIEVQILADQHGNVIHLGERECSIQRRHQKLIEEAPSPALNEEMREELGKLAVKGAREIGYTNAGTFEFLYENGNFYFLEINSRLQVEHTITEVVTGIDIVKYQIRIAYGEELRHGQEDVAIRGHAIECRINAEDPVNFYPRSGRILHYRSPGGIGIRVDSGIHMGYRIPEEYDSMISKLIAYGETREEAIARMKRALYEYIIEGVETNIPFHFAVLNDEEFVRGNIHTKFVEERNIAEKVKEYLRIFRPIKARLDEIFMESEFTWEEISAIVTAIDAYEQELERGIEERIWQAIFSLGA
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
What are the official names of this protein?
Pyruvate carboxylase subunit A, Pyruvic carboxylase A.
Protein: PCNA_METHJ
Sequence: MLKATISADIFKDTVDALSALVTECRLHFSETEVWARAVDTANVAMIILTLKKEAFSQFEATTGEIGLDIAKLKNTYSMMGKASDIRLEHQEGANKIEVTFEGYHYSITLLDSNTIKKDPNAPGIQLPGQVTISGSELYNVIKSASIVSDKIWFAIEPEKKEFVLYAEGDSDNIRRAFSAGEVIASNWEPAKSLFSIDYLKDMGKVMSHAEKVTIDLGVDHPVKFSFEIAGGNGQVEYLLAPRIEAD
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: ANP2_LYCDA
Sequence: NKASVVANQLIPINTALTLIMMKAEVVTPMGIPAEDIPRIIGMQVNRAVPLGTTLMPDMVKNYE
What is the function of this protein?
Contributes to protect fish blood from freezing at subzero sea water temperatures.  Lowers the blood freezing point.  Binds to nascent ice crystals and prevents further growth (By similarity).
What are the official names of this protein?
Ice-structuring protein RD2, ISP RD2, Antifreeze peptide RD2.
What is the protein family that this protein belongs to?
Belongs to the type-III AFP family.
What are the subcellular locations of this protein?
Secreted.
Protein: UREF_RHIEC
Sequence: MSEDRELQALLRLTAWLSPAFPIGSFAYSGGLERAVADGLVTDAASLANWIGTLIGHGSVWNDAVLLTESHRRQAEAPGLAEIAALAEALAGSRERHQETMLLGEAFLLAARAWPDEVFERLPGKTAYPIAVGAVAGAHGIGPEKVLAVFLHAYASQAVSSGIRLGVAGQKDGVAVLAGLEEQIAGTARRAAASTLDDLGSATVQADIASLRHETQTTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAPA_CAMHC
Sequence: MNRRDFIKSTAAAAACASAGIALPANLNAEENHGWRWDKAVCRFCGTGCGIMVATKNGKIVAVKGDPEAPVNRGLNCIKGYFNAKIMYGDDRITEPLLRVNSKGEFDKHGKFAPVSWKKAFDVMEKEFKKAYKEKGPTGIAVFGSGQYTIQEGYAAAKLVKAGFRSNNIDPNARHCMASAVVGFMQVFGIDEPSGCFDDIELTDTIVTWGANMAEMHPILWSRVNDRKLSAPEKVKVVNLSTFSSRTSSIADIEIIFRPSTDVAIWNYIAREIVYNHPEAIDTEFLKNCEFATGPVDIGYGMRNNPNHPKFSEAEKDTVSHQVSKKLSQAEGVSLAYLGLKAGDTLEMKNAKKAGKHWAISFEEFKKALAPYTLDYVAEIAKGDENESIEQFKEKLQNLANLYIEKNRKIVSFWTMGFNQHTRGTWVNEQSYMVHFLLGKQASPGNGAFSLTGQPSACGTAREVGTFCHRLPADMVVANPKHREITEKIWKLPAGTINPKNGSHFVGLMRDLEDGKVKFAWVQVNNPWHNTANANHWIKAAREMDNFIVVSDCYPGISAKVADLILPSAMIYEKWGAYGNAERRTQHWRQQVLPVGDAMSDTWQILEFAKRFKLKDVWGEQKIDDKLTLPNVLEEAKTMGYDENATLFDILFANDYYKGFKPEKIKFDNSEVNGDTRNVKGSDGEVFKGYGFFIQKALWEEYRKFGLGHGHDLADFDTYHKVRGLKWPVVDGKETSWRFNKKYDPYAKKEETSGDFAFYGNKNKKLDKGDLIGIKGEDKVDINNKAKIFFRPYMDPPEIPSEEYPFWLCTGRVLEHWHSGTMTMRVPELYRAVPEALCYMNPLDAEKLKLSQGDTIWIESRRGKVKVKIDTRGRNIPPVGLVYVPWFDENVFINKVTLDATCPLSSETDYKKCAVKIYKA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y4129_BACCZ
Sequence: MEENQITIVDEKGNEHLCEIIFTFDAEKFGKKSYVVFSPIGEVDEDGDQIYDAMAYEQNEEEGGTLLPIESEEEWEMVQEMFNTLADEQEAE
What are the official names of this protein?
UPF0473 protein BCE33L4129.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: CML10_ORYSJ
Sequence: MVKIKMPALFRRRSGSKSPPLPQADPASGGGSPAPTPEEEMERVFRKFDANGDGRISRSELGALFESLGHAATDDELARMMAEADADGDGFISLDEFAALNATASGDAAAVEEDLRHAFRVFDADGNGTISAAELARVLHGLGEKATVQQCRRMIEGVDQNGDGLISFEEFKVMMAGGGSFAKIA
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML10, Calmodulin-like protein 10.
Protein: DUS2_YEAST
Sequence: MVTYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCVRKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDGPSWVVACREFIQWATKFDNHIGNTKYMLSRIVPGKSVFFQYFARCKSPEEVSFVLKQLNDDGSAQTDPSEYLENCRAQEKALKNANAIAKQKRKQTDHIGSDTKKQKVVPLPTDI
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:12003496, PubMed:14970222).  Specifically modifies U20 in cytoplasmic tRNAs (PubMed:12003496, PubMed:14970222).  Also able to mediate dihydrouridylation of some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(20) synthase [NAD(P)+], mRNA-dihydrouridine synthase DUS2, tRNA-dihydrouridine synthase 2.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MAP22_ASPFC
Sequence: MAAQVSEKLQDLHLNGLNGDAKSNATVIGQTEAGEAEDDSDDEKEDGNTAPEAGAGGGAYLHVWVIFEMPVSQALGMLAYNSRIPAAKKKKRKSKKKKKGGAKVQSSPPRVPVSNLFPNNQYPEGEIVEYKNENSYRTTNEEKRYLDRMNNNFLQEYRQAAEVHRQVRQYAQKTIKPGQTLTEIAEGIEDAVRALTGHQGLEEGDNLKGGMGFPCGLSINHCAAHYTPNAGNKMVLQQGDVMKVDFGAHINGRIVDSAFTMTFDPVYDPLLEAVKDATNTGIREAGIDVRMSDIGAAIQEAMESYEVELNGTMYPVKCIRNLNGHNIDRHIIHGGKSVPIVKGSDQTKMEEGETFAIETFGSTGKGYVREDMETSHYALIPDAPSVPLRLSSAKNLLNVINKNFGTLPFCRRYLDRLGQEKYLLGLNNLVSSGIVQDYPPLCDVKGSYTAQFEHTILLRPTVKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-2, MAP 2-2, MetAP 2-2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.