PharMolix/UniProtQA huggingface dataset:
Protein: Y1220_METCA
Sequence: MAGHSKWANIQHRKGAQDAKRGKLFTKLIREITVASRTGGPDPGNNPRLRTAIDKALVANMSKDTIERAIKKGSGAADGDNYEEVRYEGYGPGGIAVLVDCLTDNRNRTVAEVRHAFSKAGGNLGTDGSVAYLFSKTGVVSFSADLGEDRVMEPALDAGADDVVVNEDGSVDVLTAPDQFEAVRDALEAAGLTPESAEVTMRASTSVKLDKEDAEKMIRLLERLEDLDDVQNVYSNADISEDILAELG
What are the official names of this protein?
Probable transcriptional regulatory protein MCA1220.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH5_ARATH
Sequence: MATTSSNPLLLSSNFLGSQIIISAPTPKTTTKSLPFSVISRKRYQISQSEKLMKSLPSQAALAALLFSSSSPQALAVNEPVQPPAPTITAEAQSPNLSTFGQNVLMTAPNPQAQSSDLPDGTQWRYSEFLNAVKKGKVERVKFSKDGSVLQLTAVDNRRATVIVPNDPDLIDILAMNGVDISVSEGEGGNGLFDFIGNLLFPLLAFGGLFYLFRGGQGGAGGPGGLGGPMDFGRSKSKFQEVPETGVTFGDVAGADQAKLELQEVVDFLKNPDKYTALGAKIPKGCLLVGPPGTGKTLLARAVAGEAGVPFFSCAASEFVELFVGVGASRVRDLFEKAKSKAPCIVFIDEIDAVGRQRGAGMGGGNDEREQTINQLLTEMDGFSGNSGVIVLAATNRPDVLDSALLRPGRFDRQVTVDRPDVAGRVQILKVHSRGKAIGKDVDYEKVARRTPGFTGADLQNLMNEAAILAARRELKEISKDEISDALERIIAGPEKKNAVVSEEKKRLVAYHEAGHALVGALMPEYDPVAKISIIPRGQAGGLTFFAPSEERLESGLYSRSYLENQMAVALGGRVAEEVIFGDENVTTGASNDFMQVSRVARQMVERFGFSKKIGQVAVGGAGGNPFLGQSMSSQKDYSMATADVVDAEVRELVEKAYVRAKEIITTQIDILHKLAQLLIEKETVDGEEFMSLFIDGQAELYVS
What is the function of this protein?
Part of a complex that function as an ATP-dependent zinc metallopeptidase.  Involved in the thylakoid formation and in the removal of damaged D1 in the photosystem II, preventing cell death under high-intensity light conditions.  Not involved in the degradation of the light-harvesting complex of photosystem II (LHC II) or in thermotolerance.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FTSH 5, chloroplastic, AtFTSH5, Protein VARIEGATED 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein; Stromal side.
Protein: ILVD_ALBFT
Sequence: MDIKPVILNPRSKNITEGKSRAPNRSMYYAMGYEADDFKKPMIGVANGHSTITPCNSGLQKLADAAIAAIEEAGGNAQVFGTPTISDGMSMGTEGMKYSLVSREVISDCIETCVQGQWMDGVLVIGGCDKNMPGGLMGMLRANVPAIYVYGGTILPGHYKGQDLNIVSVFEAVGENAAGRMSDEDLLEIERRAIPGPGSCGGMYTANTMSSAFEALGISLVYSSTMANPHDEKLNSAQESAKVLIEAIKNDLKPRDIVTRKSIENAIAVVMAIGGSTNAVLHFLAIAHAAGVEWTIDDFERVRQKTPVLCDLKPSGKYLAVDLHRAGGIPQVMKMLLSAGLLHGDCITITGQTVAEVLKDVPDAPRADQNVIRPMNKPMYAQGHLAILKGNLAPEGCVAKITGLKNPVMTGPARVFEDEQSALAAILANKIVAGDVMVLRYLGPKGGPGMPEMLAPTGALVGQGLGESVGLITDGRFSGGTWGMVVGHVAPEAAAGGLIALIEEGDSITIDAHQLLLQLNVSDDIIAKRRSVWTAPQPRYTRGVQAKFAFNASTASKGAVLDNY
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CP7A1_MOUSE
Sequence: MMSISLIWGIAVVVSCCIWFIIGIRRRKVGEPPLDNGLIPYLGCALKFGSNPLEFLRAKQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPSDGNTTENINKTFNKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSAVWVTEGMYAFCYRVMFEAGYLTLFGKDISKTDSQRAFIQNNLDSFKQFDQVFPALVAGVPIHLFKTAHKARERLAESLKHKNLYMRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLVILWASQANTIPATFWSLFQMIRSPEAMKAASEEVNGALQSAGQELSSGGNAIYLDQEQLNNLPVLDSIIKEALRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYRNGNKLKYFYMPFGSGATICPGRLFAVQEIKQFLILMLSYFELELVESHTKCPPLDQSRAGLGILPPLNDIEFKYKLKH
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity).  Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis.  Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting step in cholesterol catabolism and bile acid biosynthesis (Probable).  7-alpha hydroxylates several oxysterols, including 4beta-hydroxycholesterol and 24-hydroxycholesterol.  Catalyzes the oxidation of the 7,8 double bond of 7-dehydrocholesterol and lathosterol with direct and predominant formation of the 7-keto derivatives (By similarity).
What are the official names of this protein?
Cytochrome P450 7A1, 24-hydroxycholesterol 7-alpha-hydroxylase, CYPVII, Cholesterol 7-alpha-hydroxylase, Cholesterol 7-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: YLD2_SCHPO
Sequence: MGFIKSTLLATVTVFVGLCGINRFFTLPKCIRYHFRYFACHTFLAISSAYGVIASVVARLCGYPVMGQYLTAKAYYGLASTILDFRFKIENEEILRKHKSAVLVVNHQSELDILAIGRTFGPNYSVIAKKSLRYVPILGWFMILSDVVFIDRSRRSDAIQLFAKAARRMRKENISIWVFAEGTRSYSLKPCLLPLKKGAFHLAVQAQVPIIPIAIQTYGHLFHPPTKVFNKGEALIKVLDPIPTEGKTAEDVNDLLHETETAMNNALVEIDDYGKVKKQ
What are the official names of this protein?
Uncharacterized acyltransferase C1851.02.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DRC5_MACFA
Sequence: MQETVTTSALLDPSHSSVSTQDKSSTGGHTSSTGPQPSKPSITPVSAKSRNPHPGANFHRMRRIIAEDPEWSLAIVPLLTELCIQHIIRNFQNNPILKQMLPEHQQKVLNHLSPDLPLAVTSNLIDNENYWLRCCMQRWPVCHVAHHGGSWKRMFFERHLENLLKHFIPGTTDPAVILDLLPLCRNYVRRVHVDQFLPPVQIPAQLRPGDQSDSGSEGEMEEPTVDHYQLGDLVAGLSHLEELDLVYDVKDCGMNFEWNLFLFTYRDCHSLAAAIKACHTLKIFKLTRSKVDDDKARIIIRSLLDHPVLEELDLSHNLIGDRGARGAAKLLNHSRLRVLNLANNQVRAPGAQSLAHALAHNTNLISLNLRLNCIEDEGGQALAHALQTNKCLTTLHLGGNELSEPTATLLSQVLAINTTLTSINLSCNHIGLDGGKQLLEGMSDNKTLLEFDLRLSDVAQESEYLIGQALYANREAARQRALNPSHFMSTITANGPENSVG
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.  May play a role in the assembly of N-DRC.  May be required for sperm motility.
What are the official names of this protein?
Dynein regulatory complex subunit 5, T-complex-associated testis-expressed protein 1, Tcte-1.
What is the protein family that this protein belongs to?
Belongs to the DRC5 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Detected along the length of the sperm flagellum.
Protein: CBR4_BOVIN
Sequence: MDKVCAVFGGSRGIGRAVARLMAQRGYRLAIVARNLEGARAAAGDLGGDHLALSCDVAKEHDVQNTFEEIEKNLGRVNFLVNAAGINRDNLLVRTNTEDMLSQLHTNLLGSMLTCRAALKTMIKQQRGSIVNVGSVVGLKGNSGQSVYSASKGGLVGFSRALAKEVAKKKIRVNVVAPGFIHTDMTKDLNEELLKKNIPLGRFGDALDVAQAAVFLLESPYVTGHVLVVDGGLQLTM
What is the function of this protein?
Component of the heterotetramer complex KAR (3-ketoacyl-[acyl carrier protein] reductase or 3-ketoacyl-[ACP] reductase) that forms part of the mitochondrial fatty acid synthase (mtFAS).  Beta-subunit of the KAR heterotetramer complex, responsible for the 3-ketoacyl-ACP reductase activity of the mtFAS, reduces 3-oxoacyl-[ACP] to (3R)-hydroxyacyl-[ACP] in a NADPH-dependent manner with no chain length preference, thereby participating in mitochondrial fatty acid biosynthesis.  The homotetramer has NADPH-dependent quinone reductase activity (in vitro), hence could play a role in protection against cytotoxicity of exogenous quinones.  As a heterotetramer, it can also reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase, 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit, KAR beta subunit, Carbonyl reductase family member 4, CBR4, Quinone reductase CBR4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LEUC_MAGMM
Sequence: MSAQTLFEKIWNAHLIRTDEDGTSLIYIDRHLVHEVTSPQAFEGLRLAGRKVRHPEATFAVPDHNVPTKDLAGGIKDPVSKLQVDTLASNCQAFGITEFGVGDLRQGVVHVMAPEQGISLPGFTMVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLMQKKPKTMLIQVEGELPAGSTAKDIILYIIGNIGTAGGTGYVLEFGGSAIQALSMEGRMTVCNMAIEAGARAGMVAVDEKTIAYVQGRPYAPKGEAWEKAVAQWQTLKSDEGAPFDAVVTLDARNIAPQVTWGTSPELVAPVDGCVPNPTDEPNGVKRGAMEKALAYMGLQAGTPMTEIAVDKVFIGSCTNSRIEDLRAAAVAVAGKKVAASIKLALVVPGTGLVKQQAEQEGLDKIFMEAGFEWREPGCSMCLAMNNDVLEPGERCASTSNRNFEGRQGKDSRTHLVSPAMAAAAAIAGHFVDIRNG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PHYDA_ECOLU
Sequence: MRVLIKNGTVVNADGQAKQDLLIESAIVRQLGNNISPQLPYEEIDATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVVIIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL
What is the function of this protein?
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'-position.  Has no activity on dihydropyrimidines.  The physiological function is unknown.
What are the official names of this protein?
D-phenylhydantoinase, Hydantoin-utilizing enzyme HyuA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: Y2205_ALKEH
Sequence: MNRRRPSAPAPHLETGNRGERRALEHLTGQGLELLECNFRCRAGEIDLIMRDGEVVVFVEVRVRTHPGYGGALASITPAKQRRLARAAARWLQRHRLTQRAVCRFDVVTFDGERPQWLRHAFTAPG
What are the official names of this protein?
UPF0102 protein Mlg_2205.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: KCC2D_CAEBR
Sequence: MMNACTKFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKAAISAVKMVTRMSGVLRTSDSTGSVASNGSTTHDTSQIAGTSSQPTSPAAEGAILTTMIATRNLSNLGRNLLNKKEQGPPSTIKESSESSQTIDDNDSEKAQKQDIVRVTQTLLDAISCKDFDTYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFDGNRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDRNGEAHTRQSQESRVWSKKQGRWLCVHVHRSTQPSTNTTVSEF
What is the function of this protein?
Role in locomotion and neuronal cell fate specification.  Required for the regulation of synaptic density, egg laying, defecation, and meiotic maturation.  Required for viability under chronic osmotic stress in which it acts downstream of osr-1.  Regulates the synaptic trafficking of glr-1.  Bidirectional modulator of neurotransmitter release with negative modulatory effects mainly mediated via slo-1 activation.  May suppress the functional response to an internal pacemaker, perhaps by modulating the activity of the IP3 receptor (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II, CaM kinase II, Uncoordinated protein 43.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, axon. Perikaryon. Note=Localizes at or near the Golgi apparatus. Localizes to post-synaptic regions and is enriched in punctate structures in axons of AWC neurons where it co-localizes with tir-1. Localization is regulated by tir-1.
Protein: YKL1_YEAST
Sequence: MRKIARLLNWVSIDLLILVECFHQKGLLHHRLSLLVQQHLLHRDEVGYDGYYDELCSYYTAILHPRPPLHRLRHHHYSGVDSLPLSNAMTVTLTVPPLHVVVCRLHFSLPV
What are the official names of this protein?
Putative uncharacterized protein YKL111C.
Protein: MNMA_CHLPB
Sequence: MMKDKEHVIVGISGGVDSAVAACILIENGYRVTGLHIKVLDHSDDSLHLEKSPLIISDRKEFRFPVFSLNLSGSFRRDVIDYFLQDYLSGRTPNPCMVCNKLIKWKGLLKGADLLQATLVATGHYARIDCGREKCRLLKGTDSQKDQSYFLWMLSSEELSKTLLPVGNLTKQEVRELARRFGVRAAEKKESQEICFVPDNDYREVVKSSRPGLAEKLTGGEIIDTEGKVIGHHAGYPFYTIGQRKGLGISSPEPLYVNRLDPEKNRIRVGGKAMLQCRKLIAGQMNWTGISPPETSTRAAARIRYRDTGEACTIVPVEKERFEVIFDKPKQSVTPGQAVVFYRDDEVIGGGIIVEAISE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM12_YEAS6
Sequence: MSFDINWSTLESDNRLNDLIRKHLNSYLQNTQLPSYVSNLRVLDFDLGKVGPAITLKEITDPLDEFYDSIREEADQETEENNDNKEDSEHICPDRTIANHEGPKDDFEAPVVMPSPNDIQFLLEVEYKGDLLVTIGADLVLNYPVEKFMTLPVKLSISDIGLHSLCIVACLSKQLFLSFLCDVSDPALDDNQTVLDPKGPILAATKPLERISIVRSMKIETEIGEQYQGQGSVLRSVGELEQFLFTIFKDFLRKELAWPSWINLDFNDGDE
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RK24_PEA
Sequence: MVAMAMASLQSSMSSLSLSSNSFLGQPLSPITLSPFLQGKPTEKKCLIVMKLKRWERKECKPNSLPVLHKLHVKVGDTVKVISGHEKGQIGEITKIFKHNSSVIVKDINLKTKHVKSNQEGEPGQINKVEAPIHSSNVMLYSKEKDVTSRVGHKVLENGKRVRYLIKTGEIIDSEENWKKLKEANKKTAEVAAT
What is the function of this protein?
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L24, chloroplastic, CL24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRPF_BORPE
Sequence: MRTRVKICGLTREQDIASAVQAGADAIGFVFYPASKRHVDPARAAQLRREVPAFVDVVALFVNPRPDEVQAVLDHVAPDLLQFHGDETPQDCGRYGRRYLRAFRAGAPGLDSAAGLAAACRQYADAAGWLFDSYSAGYGGSGQGFDHGLLAGVQADPASCAIVLAGGLHPGNVADAVRAVRPWAVDVSSGVEDAPGIKSAGKIRQLMAAIKSVDQVAR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: GP153_HUMAN
Sequence: MSDERRLPGSAVGWLVCGGLSLLANAWGILSVGAKQKKWKPLEFLLCTLAATHMLNVAVPIATYSVVQLRRQRPDFEWNEGLCKVFVSTFYTLTLATCFSVTSLSYHRMWMVCWPVNYRLSNAKKQAVHTVMGIWMVSFILSALPAVGWHDTSERFYTHGCRFIVAEIGLGFGVCFLLLVGGSVAMGVICTAIALFQTLAVQVGRQADRRAFTVPTIVVEDAQGKRRSSIDGSEPAKTSLQTTGLVTTIVFIYDCLMGFPVLVVSFSSLRADASAPWMALCVLWCSVAQALLLPVFLWACDRYRADLKAVREKCMALMANDEESDDETSLEGGISPDLVLERSLDYGYGGDFVALDRMAKYEISALEGGLPQLYPLRPLQEDKMQYLQVPPTRRFSHDDADVWAAVPLPAFLPRWGSGEDLAALAHLVLPAGPERRRASLLAFAEDAPPSRARRRSAESLLSLRPSALDSGPRGARDSPPGSPRRRPGPGPRSASASLLPDAFALTAFECEPQALRRPPGPFPAAPAAPDGADPGEAPTPPSSAQRSPGPRPSAHSHAGSLRPGLSASWGEPGGLRAAGGGGSTSSFLSSPSESSGYATLHSDSLGSAS
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 153, G-protein coupled receptor PGR1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDK2H_THEAN
Sequence: MRRYHKMEKIGEGTYGVVYKAQNNHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNIVWLRDVIHSEKCLTLVFEYLDQDLKKLLDACDGGLEPTTAKSFLYQILRGISYCHDHRILHRDLKPQNLLINREGVLKLADFGLARAFAIPVRSYTHEVVTLWYRAPDVLMGSKKYSTAVDIWSVGCIFAEMINGVPLFPGISEQDQLKRIFKILGTPNVDSWPQVVNLPAYNPDFCYYEKQAWSSIVPKLNESGIDLISRMLQLDPVQRISAKEALKHDYFKDLHRPSEFLNGVH
What is the function of this protein?
Serine/threonine-protein kinase (By similarity).  Involved in the control of the cell cycle.  Required for entry into S-phase and mitosis (By similarity).  Probable component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 2 homolog, Cell division control protein 2 homolog, cdc2-related kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAZF1_MYCBO
Sequence: MNAPLRGQVYRCDLGYGAKPWLIVSNNARNRHTADVVAVRLTTTRRTIPTWVAMGPSDPLTGYVNADNIETLGKDELGDYLGEVTPATMNKINTALATALGLPWP
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Acts as an endoribonuclease on single-strand RNA, cleaving between the first and second bases in the sequence UCGCU.  Neutralized by coexpression with cognate antitoxin MazE1.
What are the official names of this protein?
Endoribonuclease MazF1, Toxin MazF1, mRNA interferase MazF1.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: ACSF_RHOPT
Sequence: MIPMEGGAQGALRTRPDIKGSVDSLNIAKQDTILTPRFYTTDYAAMDKLDVSLVRAEWTAMMNELRADYNKSHFKKTDEFLNSDLDKLPPELRAEFKDFLVSSLTAEFSGCVLYAEIKKRIKNPEIRELFGLLSRDEARHAGFINEILKDHGIGVDLSFLTKVKKYTYFRPKFIFYATYLSEKIGYARYITIYRQMERHPERRFHPIFKWFERWCNDEFRHGEAFALLMRADPSLLSGVNKLWIRFFLLAVFSTMYVRDHMRPAFYEALGVDATDYGMQVFRITTEISKQVFPVTINLDDPRFLQNLERLRIAAEKIDRSHSQGLLGKLKRPFYAASAALAFGRLFLLPAKRNELPRVIGLRPAW
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: OBG_BRUME
Sequence: MKFLDQAKIYIRSGNGGAGAVSFRREKFLEFGGPDGGDGGRGGDVWVEAVDGLNTLIDYRYQQHFKAKTGMHGMGRNMTGGKGDDVVLRVPVGTQIFEEDNETLICDITEVGQRYRLAKGGNGGFGNLHFTTSTNRAPRRANPGQEGIERTIWLRLKLIADAGLVGLPNAGKSTFLASVTAAKPKIADYPFTTLHPNLGVARIDGREFVIADIPGLIEGASEGVGLGDRFLGHVERTRVLLHLVSAQEEDVAKAYQVIRGELEAYEHGLADKPEIVALSQVDTLDPETRKAKVKALKKACGCEPLLLSAVSHEGLNDTLRQLARIIDLSRAEEAGTAQAEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSVR_COTJA
Sequence: MARLLPALLLLLLPGNVTGNGSGNGSLSRCPPGQFRCSEPPGAHGECYPQDWLCDGHPDCDDGRDEWGCGTSATPAVPTDNGTEAPTVPAPGRALPARNHGRMWMLITAVLLCCLVAVGGIAAWGKSKAKSRSDIFSLASASKELLVPDKSQADLFS
What is the function of this protein?
Responsible for susceptibility to the retrovirus subgroup A Rous sarcoma virus.
What are the official names of this protein?
Subgroup A Rous sarcoma virus receptor pg950, Low density lipoprotein receptor-related protein, Tva.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y6090_DICDI
Sequence: MKRYKRMKSVVEFCLENEKTQHKNVIQIRCIDGVSFFNLYSYNLLT
What are the official names of this protein?
Putative uncharacterized protein DDB_G0280641.
Protein: PSTB_CLOPE
Sequence: MSDKKTKIQVRDLDLFYASNHALKKINIDIKENEVTALIGPSGCGKSTFLRTLNRMNDLIPIVRIEGEIQVDGKDIYKDDDVIALRTKVGMVFQKPNLFPMSIYDNVAYGPRVHGIKDKKVLDKIVEESLRDAAIWDEVKNRLKSSALGLSGGQQQRICIARAIAMNPEIILMDEPTSALDPISTLKVEELIRKLEDKYTIVIVTHNMQQAARISDKTAFFLNGELVEFSDTNTIFTNPRDKRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HEM1_BURO0
Sequence: MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNTPEAAILSTCNRTELYCATDDRAAREGAVRWLSEYHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKDAVRTATEAGALGTYLNQLFQRTFAVAKEVRGTTEIGTQSVSMAAAAVRLAQRIFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLADLPTRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADALRRAEVEKAQKLLARGDDPAAVLEALSQALTNKLIHGPTSALNRVNGADRDSLIDLMRGFYQHAPRSNDQSGH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PGSA_ECOL6
Sequence: MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVAAVLTLWSMLQYLSAARADLLDQ
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.