PharMolix/UniProtQA huggingface dataset:
Protein: RICI_RICCO
Sequence: MKPGGNTIVIWMYAVATWLCFGSTSGWSFTLEDNNIFPKQYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAPPPSSQFSLLIRPVVPNFNADVCMDPEPIVRIVGRNGLCVDVRDGRFHNGNAIQLWPCKSNTDANQLWTLKRDNTIRSNGKCLTTYGYSPGVYVMIYDCNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQGWLPTNNTQPFVTTIVGLYGLCLQANSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKILSCGPASSGQRWMFKNDGTILNLYSGLVLDVRASDPSLKQIILYPLHGDPNQIWLPLF
What is the function of this protein?
Binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain.  Also responsible for cell agglutination (Lectin activity).
What are the official names of this protein?
Ricin.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: LMNA_CHICK
Sequence: MSTPSQRRSGRGGGPSGTPLSPTRITRLQEKEDLQELNDRLAVYIDKVRSLELENAGLRLRITESEEVVSREVSGIKAAYEAELADARKTLDSVAKERARLQLELSKVREEHKELKARNAKKEADLLAAQARLKDLEALLNSKEAALSTALGEKRNLENEVRDLRAQVAKLEGALSEAKKQLQDEMLRRVDAENRLQTLKEELEFQKNIYSEELRETKRRHETRLVEIDNGRQQEFESKLAEALQDLRRQHEDQIRHYRDELEKTYGAKLENAKQSAERNSSMAGAAHEELQQTHIRIDSLSAELSQLQKQLAAKEAKLREVEEALSREREGGRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEINAYRKLLEGEEERLRLSPSPSSQRGARSSGLQHSGAGSAKKRRLEDGEGREGREGRTSFSHHARTSGRVGVEEVDLEGRFVRLRNKSNEDQALGNWQVKRQNGDDPPLTYRFPPKFTLKAGQAVTIWASGAGATHSPPSDVVWKAQSSWGSGDSLRTALINSNGEEVAMRKLVRTVIINDDDEDEEDDEVSIHHRHHHSGCSGSADPAEYNLRSRTVLCGTCGQPADKGSAAAASSASSASTVTVSRGYRSSGGGIGEGLLGRSYVLGGAGPRRQAPAPQGCSIM
What is the function of this protein?
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
What are the official names of this protein?
Lamin-A.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAD_STAA2
Sequence: MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITTTINEALVDADVSMEDIDAIAVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGETRDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVATSFQNSVVEVLTFKAIQACKEYSVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQGRFADLALNGHSNIDLEEYSAE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAYAN_DROME
Sequence: MAMISARRYFLLGLLVLTTSAYVTVGDEGDPCQVRSDIPGICLSSSACENIRGYLKSGTLSTSQVPSCGFGAREEIICCPTVACCATDRGREVQFHATSSERSSLPEPKREPTPEPEPLPPTTTEGKRERESRLDENQNFFDFNKLLSTTVKPQKTHESLKLPTQESMKTPTHESMKMPTHESMKLPTHEPMKLPIQSVGAWGIAPSKTQPIASTQRSFMEPEWGREPRIVNRPLTTPRSRPQRPNNSNFNTNPSPNNNNLIHLVNDRLREQGMQIEPAREVPMVLQTTPTPTPAPTPTQLIDPFEPYRFRGQDRDKDTQPQEPWNDVSNNLDADPAPSIFNPAETRPTTPNPNPSRVNLPEKERPSVAACEKIRSGGKPLTVHILDGERVDRGVYPHMAAIAYNSFGSAAFRCGGSLIASRFVLTAAHCVNSDDSTPSFVRLGALNIENPEPGYQDINVIDVQIHPDYSGSSKYYDIAILQLAEDAKESDVIRPACLYTDRSDPPANYKYFVAGWGVMNVTNRAVSKILLRAALDLVPADECNASFAEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGGPLILEIDDVDGTYSIVGVISSGFGCATKTPGLYTRVSSFLDYIEGIVWPSNRF
What is the function of this protein?
Serine protease which, by converting prophenoloxidase 1 (PPO1) into its active form, plays an essential role in the melanization immune response to physical or septic wounding.  May function in diverse PPO1-activating cascades that are negatively controlled by different serpin proteins; Spn27A and Spn28D in the hemolymph, and Spn28D and Spn77BA in the trachea.  Also required in the systematic wound response by mediating the redox-dependent activation of the JNK cytoprotective cascade in neuronal tissues after integument wounding.
What are the official names of this protein?
Serine protease Hayan.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: B2L12_HUMAN
Sequence: MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKFVRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPRSPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQRLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVRLSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTLAGLSVEHVHSFTPWIQAHGGWEGILAVSPVDLNLPLD
What are the official names of this protein?
Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich protein.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
Protein: ENO_EIMTE
Sequence: MVAIVEVKAREILDSRGNPTVEVDLKTEQGCFRAAVPSGASTGIYEALELRDGDKTRYNGKGVLKAVENVNKVLAPALVGKDCREQAALDRLMVEELDGSKNEWGWSKSVLGANAILAVSMALCRAGAAAKGIPLYKYVAQLAGHEAPEFVLPVPCFNVLNGGKHAGNSLAMQEFMVAPVGARSFGEALRMGAEVYQALQRLLKAKFGLAATNVGDEGGFAPDIKDPREALGLLVEAIRAAGHEGKVKIMADVAASEFYSKEAKSYDLDFKSPAADAHRLLTGDQLKDLFKEWSEEFPIVSIEDPFDQDDFSSYAALTAEIGSKVQVVGDDLLVTNPARIRKALQHKACNALLLKVNQIGSITEAIEACKLAQASGWGVMVSHRSGETEDSFIADLVVGLRTGQIKTGAPCRSERLCKYNQLLRIEEQLQGRCTYAGENFRNPSN
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_PROM2
Sequence: MNKTITPSLETIERNWFLVDAKNKTLGRLATEIATLLRGKNKPTFTPHLDTGDFVIVVNAEKVEVTGKKASQKLYRRHSGRPGGMKIEKFESLKERIPERIIEQAVKGMLPHNSLGRQQFKKLKVYKGADHPHAAQNPVLLNS
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CRA2_HOMGA
Sequence: DGIPSFVTAGKCASVANQDNFDLRRYAGRWYQTHIIENAYQPVTRCIHSNYEYSTNDYGFKVTTAGFNPNDEYLKIDFKVYPTKEFPAAHMLIDAPSVFAAPYEVIETDYETYSCVYSCITTDNYKSEFAFVFSRTPQTSGPAVEKTAAVFNKNGVEFSKFVPVSHTAECVYRA
What is the function of this protein?
Binds the carotenoid astaxanthin (AXT) which provides the blue coloration to the carapace of the lobster.
What are the official names of this protein?
Crustacyanin-A2 subunit.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: Y4100_RICPU
Sequence: MSEVVVKEQLEQYISKIERLEQEKADLSQEVKDIFQDASSHGFDVKAMKSILKLKKLDKDKLAEQDAMLELYRDTLGI
What are the official names of this protein?
UPF0335 protein RPR_04100.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: SKAP1_HUMAN
Sequence: MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER
What is the function of this protein?
Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway.  Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells.  May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
What are the official names of this protein?
Src kinase-associated phosphoprotein 1, Src family-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa, SKAP-55, pp55.
What is the protein family that this protein belongs to?
Belongs to the SKAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Upon T- cell stimulation, translocates to lipid rafts at the cell membrane.
Protein: VM31_CRODC
Sequence: EQQKYLNAKKYVKLFLVADYIMYLKYGRNLTAVRTRMYDIVNVITPIYHRMNIHVALVGLEIWSNTDKIIVQSSADVTLDLFAKWRATDLLSRKSHDNAQLLTGINFNGPTAGLGYLGGICNTMYSAGIVQDHSKIHDLVAIAIAHEMGHNLGMDHDKDTCTCGTRPCIMAGVLSCEASFLFSDCSQKDHQEFLIKNMPQCILKKPLKTDVVSPAVCGNYFVEVGEECDCGSPRTCRDPCCDAATCKLRQGAQCAEGLCCDQCRFKGAGTECRAAKDECDMADVCTGRSTECTDRFQRNGQPCKNNNGYCYNGKCPIMADQCIALFGPGATVSQDACFQFNREGNHYGYCRKEQNTKIACEPQDVKCGRLYCFPNSPENKNPCNIYYSPNDEDKGMVLPGTKCADGKACSNGQCVDVT
What is the function of this protein?
Snake venom zinc metalloprotease that induces apoptosis in vascular endothelial cells (VEC), without degrading the extracellular matrix (it cannot cleave collagen) or inhibiting adhesion of VEC.  Has also fibrinogenolytic and hemorrhagic activities (By similarity).
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like crotastatin, Crotastatin-1, Snake venom metalloprotease, SVMP, Vascular apoptosis-inducing protein-like, VAP-like.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIc sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRC_PSELT
Sequence: MDLLHKAKLAPLLPGVYIFYGKNKEYIYVGKAKRLRNRLLSYFNRSNGKYSKKIQAIVNEAEELDYIVVSNEREALLLEANLIFNHKPKYNVMLKDAEFYPYIEITKELFPAVQIVRIRSTGGEYFGPYTDVKFVKDLIDCLQQVYQFRTCRRDMSKSTKPCMEFYMHRCAAPCTGDLEPDSYINSSIQPLRRVLNGDISETLDLIEEKMKKHAKMMDFENAAKYRDLLVKFENVMQRQGVVLEQWRNLDVIGRFKNSYAVLRIRGGHVVGKLSYELDSTKLEDFIFHYYMVGKNELPEAVILERNINFDAEIYFGRPRDKLEEELLHKARENAKNQAYTSGLRKDLLNKMVKVLNLNRYPMKIEGFDVSHLHGKLTVASVVVFFDGLPRKNEYRHYRFNSDRIDDFLTLKELVKRRYSKHELPDMIFVDGGTGQINAVVEALMEIGKECDVVGLAKQNEIVCTRFGELILPFDSPILRTLVRIRDEAHRFANSFHRKLRRKSALSSILDEIPGIGPKRKKKLIEAFGSVKNIRSATLQEIAEVLGSRKLAAEILSRL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA5A_NAJSP
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCNKLVPLFYKTCPAGKNLCYKMFMVSNLTVPVKRGCIDVCPKNSALVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 5a, Cardiotoxin 5a, CTX-5a, Ctx5a.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: BCHC_RHOCA
Sequence: METQVVIMSGPKAISTGIAGLTDPGPGDLVVDIAYSGISTGTEKLFWLGTMPPFPGMGYPLVPGYESFGEVVQAAPDTGFRPGDHVFIPGANCFTGGLRGLFGGASKRLVTAASRVCRLDPAIGPEGALLALAATARHALAGFDNALPDLIVGHGTLGRLLARLTLAAGGKPPMVWETNPARRTGAVGYEVLDPEADPRRDYKAIYDASGAPGLIDQLVGRLGKGGELVLCGFYTVPVSFAFVPAFMKEMRLRIAAEWQPADLSATRALIESGALSLDGLITHRRPAAEAAEAYQTAFEDPDCLKMILDWKDAK
What is the function of this protein?
This protein catalyzes the penultimate step in bacteriochlorophyll a biosynthesis.
What are the official names of this protein?
2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase.
Protein: Y697_GEOKA
Sequence: MTHAHITSWLITIVLFFLAVSMERQGAGKAKIVQMVLRLFYILTIVTGLLLLHSIASISALYWLKALAGLWVIGAMEMVLAAEKKGKSAAARWTQWVIALAVTLFLGLLLPLGFDLF
What are the official names of this protein?
UPF0344 protein GK0697.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ETT1_PICGU
Sequence: MAKRQLGLGKAAKAKKQKTETSQSTAATSQKPNETLRVELNEEADADDELAQLQALWNTYSKSDKENELMVNGIIHECDRLLRNWDEKNEALPDYFHAIYALALSELAKYKPEETSQCFQMALERLDAGLAAYPKSIDVNFAKSRVLLARIPLQYISTLEVSSQVGDYPNVSEMLDEALSVYEVAETEAEARKEYSKFNEDNLDILQALDDVLDMMDNFCKKEEEEDEEKEDDDDEEEDEEEEVIQLAENHPLYHIQATDKYNFWWRNHTLKFLTNVTKRTENTTQLQRELCTRLGQSYLQEAEVPANVYTTLKYDDDYAGLGELQGLQMEEGQKLAQESFKEALKYLKKAQDDDDPDTWVNVAEAMISLGNMYEMDSPDQEKWYDEAEKILVRANKATQGKYREILENLRGEDEGDE
What is the function of this protein?
Required for correct translation termination and probably involved in regulation of hypoxic gene expression.
What are the official names of this protein?
Enhancer of translation termination 1.
What is the protein family that this protein belongs to?
Belongs to the ETT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_ACTSZ
Sequence: MSNPIYKRILLKLSGEALQGAEGFGIDPSILDRMALEIKELIAMGVEVGVVLGGGNLFRGAKLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRADVNAKLMSAFQLNGICDTYNWSEAIKMLREKRVVIFSGGTGSPFFTTDSAACLRGIEIEADVVLKATKVDGVYNCDPAKNPGAELFNTLTYADVIERELKVMDLAAFTLARDHGMPIRVFNMGKPGALREVVTGLTEGTIIS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMS_BOMOR
Sequence: MRSEKHLPPLPLLLAICCLGTLHPSSGFPQSVPSYMEALDIPESEKLAFCFSQWTALPDQEQIPSFVMDLCSSIYNRMKVNEENNHEIYKRFLFQFSRTKDPSLKTGESQIATAEYTKRDSSGIVGRPFFLFRPRNGRKVSINEH
What is the function of this protein?
Stimulates uterine smooth muscle contraction (By similarity).  Synthetic peptide NmS-17 induces calcium mobilization in CHO cells transfected with either human FM-3/GPR66 (EC(50)=0. 085 nM) or FM-4/TGR-1 (EC(50)=0. 231 nM) NmU/NmS receptors.
What are the official names of this protein?
Neuromedin-S.
What is the protein family that this protein belongs to?
Belongs to the NmU family.
What are the subcellular locations of this protein?
Secreted.
Protein: FIS_SHIBS
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: SEC24_EMENI
Sequence: MASPQGGYPPQEGYGQQPVAYGAPVQQPGEAPAPQVHTGGRKKRAYAGEAFEIGSGANAALGGQPPAGGAYGAYPPQQPAYGADPSQMAQGYAPPVAPGVAQMTQQFGAMGVTDPHLMPPQQAPQAPQAPQAPRAVPLNQLYPTDLLTQPFNVAELDYPPPPIVLAPGTSVYPSPYANCPPKYVRSTLNAVPTTHSLLKKSKLPFALVIQPYAALHDAEDQVPVIPDQVISRCRRCRSYINPFVTFLDHGHRWRCNMCNLTNDVPQAFDWDATLQKPADRALRPDLNHAVVEFVAPQEYMVRPPQPLVYLFLIDVSYASVTNGLLATSARCIKESLDRIPNADRRTRLGFIAVDSSLHYFSIPRDGSETSDPRMLVVSDLDEPFLPIPGDLLVTLSECRENIEVFLDKLQEMFQNTQNNSCAMGSALRAGYKLISPVGGKMTVLTSSLPNVGHGALTMREDKKVLGTSKESSLLQTANSFYKSFAVECSKAQVSVDMFLFSSQYQDVASLSNLPRYTGGQTYFYPGWNAARSEDAIKFAREFSDYLSSEIGLEAVLRVRATTGLRMSTFYGNFFNRSSDLCAFPAFPRDQAYVVEVAIDETVTKPVVCLQTAVLHTTCNGERRIRVLTLALPTTQNLADVYASADQQAIATFFSHKAVERTLGSGLEQAREALQAKAVELLSTYRKELAGGSVGGGGLQFPANLRGLPVLFLALIKNLGLRKSAQIPTDMRSAALCLLSTLPLPLLIQYIYPKMYSLHDMPDNAGLPDEQTGEIVLPPPINLSSERIVPYGLYLIDDGQTQFLWVGRDAVPQLLLDVFGLPDRSQLRVGKQNLPELDNDFNGRVRAVVEKSRDHRSKGVGSIVVPHLYVVKEDGEPGLRLWAQTMLVEDRADQGVSLVQWMGSLREKV
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec24.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SMC6_MOUSE
Sequence: MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRVRKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRDEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIITLQQRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDNKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSITVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS
What is the function of this protein?
Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination.  The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.  The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).
What are the official names of this protein?
Structural maintenance of chromosomes protein 6, SMC protein 6, SMC-6, mSMC6.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC6 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Chromosome. Nucleus, PML body. Chromosome, telomere. Note=Localizes to PML nuclear bodies in ALT cell lines. Associates with chromatin. Accumulates with RAD18 and the SLF1-SLF2 complex at replication-coupled DNA interstrand repair and DNA double-strand breaks (DSBs) sites on chromatin in a ubiquitin- dependent manner. Localizes in interchromatin granule clusters (By similarity). Colocalizes with SMC5 on the X-Y chromosome pair within the sex vesicle during late pachytene/diplotene (PubMed:11408570).
Protein: SYH_STRPG
Sequence: MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKDVTLHLNSLGSPESRAAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLAVEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVEGSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDVYLAVLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEAGKAVIKNNRSRQELEVSFEDMMTNFENISEQLLS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_DESVH
Sequence: MIKVKLVRSLICCNPTQRATVAALGLRKVGSEKTFKDDAAIRGMINKVKHLIEVSE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: YUZI_BACSU
Sequence: MTIFQRTIVVLIGTQLAASAVILFIFDLNSYNHFSGSFSWLHFLKELAGSFAFYLFSAGLFFLLIGLCAPSRKKKRISVHEKENSLK
What are the official names of this protein?
Uncharacterized membrane protein YuzI.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSTS_SHIFL
Sequence: MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKWADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIGGVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRRADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGYVEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWPITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWKTNIKDSSGKPLY
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HFLD_HALHL
Sequence: MSESREQEQALTLAVIMQSVQCIREVARTGDTETSRYEPLIEGLLGEYDGSTDALYGAARLAPGLRRVVEQLEDPQEADTTRYVASIFHLERRLMKRQAVLQRIAEGIEQARSQADYFENPAHTSVIRSVGDLYSQTISEMGPRLMIRGEQQHLENERNAALIRALLLCGIRGASLWRDNGGGRMTLLFRRQAIAGAARDLLEALPTEA
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AGAL_CELJU
Sequence: MRKQLLLGLGLVSALLVSVQASAQKFEQLAKTPQMGWNSWNTFGCNVDEKMIRAMADAMVTSGMKAAGYEYINIDDCWHGERDKNGFIQADKKHFPSGMKALADYVHAKGLKLGIYSDAGNTTCAGRPGSRGHEYQDALTYASWGIDYVKYDWCDTQDINPKSAYATMRDAIHKAGRPMLFSICEWGDNQPWEWAQDVGHSWRTTGDIYPCWNCEHNHGSWSSFGVLPILDKQAGLRKYAGPGHWNDMDMMEVGNGMTEEEDRAHFSLWAFMASPLIAGNDLRNMSDTTRAILTHKETIAINQDKLGIQAMKWIDEGDLEIYIKPLEKGHYAVLFLNRADDAMDYRFDWSFHYMKDDISKHEIFFDKQAFNWRNIWNGETGSTKEVLNIKVPAHGVVVLRLSPR
What is the function of this protein?
Hydrolyzes galactomannan found in plant cell wall, by cleaving alpha-1,6-D-galactose side-chains from the mannan backbone.  Appears to act in synergy with mannanase (ManA) to elicit hydrolysis of galactomannan.  Has greater activity against galactomannans with decreased degree of polymerisation values.  To a lesser extent, is also able to degrade other galactosides containing alpha-1,6-linked D-galactose, such as melibiose and stachyose.
What are the official names of this protein?
Alpha-galactosidase A, Alpha-D-galactoside galactohydrolase, Alpha-galactosidase 27A, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
Protein: COAD_FRAT1
Sequence: MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFKDNQRVKVVSFQGLLVDTAVKHNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYSKE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.