PharMolix/UniProtQA huggingface dataset:
Protein: MT25B_MOUSE
Sequence: MRGVSAHGLSHEERRQLAVDLTRVLAHYRSILDAYIIEFFTDSLWGTLPHSWQEALDGLNPPQLATLLLGMPRDGEEMRYRSVWPLTLLALKSTACALAFTRTPGFHTPSEFLENPSQSSRLTAPFRKHVKPKKQHEIRRLGELVKKLSDLTGCTQVVDVGSGQGHLSRFMSLGLGLMVKSLEGNQRLVKRAQHLDQELLKALDKMEKRHPKMVQRGPRHRPHHVVQWVSPTTLCEELLLPLERPGQSSARLLLTGLHACGDLSVALLRHFCCCPEVVALASVGCCYMKLSDPGSYPLSQWIAGLPGHELPYRLREGACHALEDYAERLHKAEPGLQTHCFRAALETVIRQVCPELRRPGVQGIPRVHELKIEEYVKQGLKRVGLDPQLPLDLAALQAHQAQENRVVAFFSLALLLAPLVETLILLDRMLYLQEQGFYAELLPIFSPELSPRNLVLVATKTPLGQAFSTLETEDN
What are the official names of this protein?
Methyltransferase-like protein 25B, Protein RRNAD1.
What is the protein family that this protein belongs to?
Belongs to the METTL25 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SPNE_AEDAE
Sequence: MSMADEDEEHTKALKAKEMMLPLFQKYNFTLKHNKLPIRHSKDDILARIRENPVIVLEGPTGCGKTTQVPQFILEEAYHRKEYCNIIVTQPRKIAAMSIAKRVSEERKCELGTLVGFKVGLKECLSPDTRLLYCTTGVLLQSLINSKTMANYTHVILDEIHEREVDMDFLLIVVRRFLATNSSKTKVILMSATIDSKAFAEYFKTPKKVGYLTAPIISVDRPRLYEVKEFYYDDLDKLRLDFAIDYENPGISSHMYTVAAKLVLVCDRLIENMHGEERMEYKPTVLIFLPGINEIDRMDHVLRETLTRIVNPKEKPNLDIHRLHSILPADEQVKVFRKPAPGQRKVILSTNIAESSITVPDVKFIIDFCLQRVLFTDTTTNFSTLRTEWASQANCIQRQGRAGRVMDGRVYRLVDRRFYENQMRFSTSPEILRCPLENVILKAKLLEMGPPHSILALAMNPPDLSDIRNTVLQLKELGALVQTVKGNYEQLDGDLTYMGRIMAKLPLDLRISKLIILGYIFSVLEESIIIAAGMNEKNIFLNQNSVRGYSQKMYWADGSGSDGIAILNAYIAWKSRKEQAGNESDMASWTRRMSLDLKCLMDMAELIREIKDRLNHVGMKEVSGPGRVVWSSREKTVILKVIMAGAFYPNYFIPMSVGGKELMERQSFTELGGRDPCNTVFFTGFDHEKYIGPLYTVQIKKLLSEGDFSKHQNMKVMYDRTTNRIFVTFLGSNDEHDQRGAFMPGKVHADVYRAIKLRKLGSRNRIMEIRTMRQRDAIEFATEMNLGHWEDANGWVPRRKVIRNAHLSVIPAIHQASMVCQVTNVIHCNKFYLRPEDTKNKDIFMDIHSKLNSRGYRLERFDPDWQFAVGQMVAAPLEEGSDRYARAVLKNYKNIRSTGDVMWTVFFLDYGHSSVLGQSAFRKLDGPLAYMKEIPQRVFEATLSEIQPSAIISPQGIWTAQSINRFKEMTLGKIFVVDVYSVVNDVASVVLKKGDEVPINSELIRLKFAQYAEESYISKLDHDMRERKQREMSLDEDVRYEVYHSSKNNQLKYEEDELEDVSPPEEKLRCKVMLSGPHSPLETTASSTVRSGVMKPVTIENDSVNSILLDSNPQDTHEKMLVGAFVHEQGNRLVVRQASMMPNIPGFGPLMALIFCPTCQMKKDEEETRVVSILTGLGCDKNTGESLFPEHDLALTLDVVLSDDDITEINALRYTMDTILHTDQDQTVPKFGDVSIENLKAKVKQYIIKILEHERKFMDIRHAPNDYDWKLVEENNAAEASSSSKKRKQDFNIYDNAIYPLLPPLGLLPVSAKQLDFLKRHCRELHKLALTDVNLPRHGITCQMCNTILETLPQLRIHLYSKLHRDRESQIKFR
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: Y2556_MYCTU
Sequence: MDTDVLDVDTARRRIVDLTDAVRAFCTAHDDGLCNVFVPHATAGVAIIETGAGSDEDLVDTLVRLLPRDDRYRHAHGSYGHGADHLLPAFVAPSVTVPVSGGQPLLGTWQSIVLVDLNQDNPRRSVRLSFVEG
What are the official names of this protein?
UPF0047 protein Rv2556c.
What is the protein family that this protein belongs to?
Belongs to the UPF0047 family.
Protein: APOA4_MIRAN
Sequence: MFLKAVVLTLSLVAVTGAQAEVSANQVATVVWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKIGQVNTYTDNLQKKLVSFAMELHERLRKDSEKLKEEIRKELEELRAGLLPHADEVSRKIGDNMHELQQRLGPYAEELRTQVNTHAEHLRNQLTAHAQRMETTLRQNVGNLQASLTPYADELKAKIDQNVEELKGHLTPYADELKVKIDQNVEDLRRSLAPYAQDVQEKLNHQLEGLAFQMKKNAEELKAKISANADELRQKLVPVAEVVRGKLRDNTEELQKSLAELSSHLDRQVEEFRRNMGPYGETFNKALLQQVEELRQKLGPYAGDVEDHLSFLEKDLRDKVNSFFSTLEEKENQDMLVAVPELQLTPVPLES
What is the function of this protein?
May have a role in chylomicrons and VLDL secretion and catabolism.  Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT.  Apoa-IV is a major component of HDL and chylomicrons.
What are the official names of this protein?
Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS7_ACIAC
Sequence: MTSSALVPSTASEGDRIAEVARNTAETRIRVRVNLDGTGNARLSSGIGFFDHMLDQIARHGLIDLDIECEGDLHIDGHHTVEDVGITLGQAFARAVGDKKGIRRYGHAYVPLDEALSRVVVDFSGRPGLHMDVKFTAGSIGQLDTQLVYEFFQGFVNHAGVTLHIDNLKGFNAHHQCETIFKAFARALRAALARDPRSAGVIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R47BP_ARATH
Sequence: MAMMHPPQPPQGSYHHPQTLEEVRTLWIGDLQYWVDENYLTSCFSQTGELVSVKVIRNKITGQPEGYGFIEFISHAAAERTLQTYNGTQMPGTELTFRLNWASFGSGQKVDAGPDHSIFVGDLAPDVTDYLLQETFRVHYSSVRGAKVVTDPSTGRSKGYGFVKFAEESERNRAMAEMNGLYCSTRPMRISAATPKKNVGVQQQYVTKAVYPVTVPSAVAAPVQAYVAPPESDVTCTTISVANLDQNVTEEELKKAFSQLGEVIYVKIPATKGYGYVQFKTRPSAEEAVQRMQGQVIGQQAVRISWSKNPGQDGWVTQADPNQWNGYYGYGQGYDAYAYGATQDPSVYAYGGYGYPQYPQQGEGTQDISNSAAGGVAGAEQELYDPLATPDVDKLNAAYLSVHASAILGRPMWQRTSSLTSQLGK
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation.
What are the official names of this protein?
Polyadenylate-binding protein RBP47B', Poly(A)-binding protein RBP47B', RNA-binding protein 47B', AtRBP47B prime, AtRBP47B'.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding RBP47 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasmic granule.
Protein: KAX_BUTOC
Sequence: TNGVPGKCTKPGGCSTYCRDTTGTMGLCKNSKCYCNNKY
What is the function of this protein?
Probable toxin that may inhibit voltage-gated potassium channels (Kv).
What are the official names of this protein?
Toxin Bot33, Potassium channel toxin alpha-KTx.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family.
Protein: ODPB_BOVIN
Sequence: MAVVAVLVRKPLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQSVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWSSEDAKGLIKSAIRDNNPVVVLENELMYGVPFELPSEAQSKDFLIPIGKAKIERQGTHVTIVAHSRPVGHCLEAATVLSKEGIECEVINLRTIRPMDIETIEGSVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial, PDHE1-B.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RISB_VEREI
Sequence: MFGADKGTADRLDGKKLHIGIVQARFNSGITNALAAACCAELLALGVQDKHIMQVQVPGALEIPVALQAMAERNHYDALIALGCIIRGQTYHFELVANESGAGVTRLALDYQIPIANAIITVENLEQAIARQSEKGADAARVAVEMANLLDALS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: AAEA_ECOLC
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRPB_PSEAE
Sequence: MTSYRNGPDAKGLFGRFGGQYVAETLMPLILDLAREYEKAKDDPAFQEELAYFQRDYVGRPSPLYFAERLTEHCGGAKIYLKREELNHTGAHKINNCIGQILLARRMGKKRIIAETGAGMHGVATATVAARFGLQCVIYMGTTDIDRQQANVFRMKLLGAEVIPVTAGTGTLKDAMNEALRDWVTNVDSTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQLAEKEGRLPDSLVACIGGGSNAMGLFHPFLDDAGVQIVGVEAAGHGIDTGKHAASLNGGVPGVLHGNRTFLLQDADGQIIDAHSISAGLDYPGIGPEHAWLHDTGRVEYTSITDDEALEAFHTCCRLEGIIPALESSHALAEVFKRAPSLPKEHIMVVNLSGRGDKDMQTVMHHMQQESKA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RSXE_ECOLC
Sequence: MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDGADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRAEAAAERALPNGETGNV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rsx electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATK_SAPSA
Sequence: MEKSQIYLELDGFQQHNFLYPLLFREYIYALAQDHGLNRSTISLENGGYDNKSSSLSGKRLITLLYQQIHLSISANDSNPNQFIGHNNNLYSQMISEGFAVIVEIPFSLQLVSFLEGKEMAKSHNFQSIHSIFPFFEDNFSHLNYVLDVLIPHPIRPEILVQTFRYWVKDASSLHLLRFFLHEYFNWNSLITPKKSISSFSTSNPRFFLFLYNFHVYEYEFLFFFLRNQSSHLRLTSSGVLLERIHFYGKVDYLVEVFANGFQDILRLYKDLFMHYVRYQGKAILASKDTPLLMNKWKNYFVNLWQWHFHVWSQPGRVHINHLHKDSINFLGYLSSRRQNPLVVRSQMLENAFLIDNAMKKFETAVPIIPMIESLTKARFCNPLGNPISKPTWADSSDCHIIGRFVRICRNLSHYHSGSSKKKSLYRIKYILRVSCVKSLVRKHKSTVRVFLKRLGSEFFQXFLTEEEXVLSLIFSRASFTWRXLYXGRVXYXDIICINDLVNHDKLXXXXXXXXXXXXXXX
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NMDA1_DROYA
Sequence: MAVAGFVFCWPLLGLTIVLLVAPIDAAQRHTASDNPSTYNIGGVLSNSDSEEHFSTTIKHLNFDQQYVPRKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDDVDVRATVELIVEFEPKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPDGVLGLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHLKLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNSDATANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNSTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIYKKHQVKKQKRLDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISLAVDKRRYPRLGQRLGPERAWPGDAADVLRIRRPYELGKPGQSPKVIATNQPGMPMPMLGKTRPQQSVLPPRYSPGYTSDVSHLVV
What is the function of this protein?
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Mediated by glycine.  This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning.  It mediates neuronal functions in glutamate neurotransmission.  Is involved in the cell surface targeting of NMDA receptors.  Plays a role in associative learning and in long-term memory consolidation (By similarity).
What are the official names of this protein?
Glutamate [NMDA] receptor subunit 1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density.
Protein: SYE_FLAJ1
Sequence: MSKQVRVRFAPSPTGPLHIGGVRTALFNYLFAKKHNGVFYLRIEDTDQTRFVPGAEAYIMEALEWLGISPEETVGKNEKFGPYRQSDRKDLYQKYADQLINSGWAYYAFDTPEALDAHRKQHEAEGKTFIYNHHNREKLDTSLVISAEETAKRIANGEHYVIRFKTPVDETLHLKDIIRGDVKFETNLLDDKVLFKSDGMPTYHLANIVDDHLMETSHVIRGEEWLPSMPLHVLLYRAFGWDAPEFAHLPLILKPVGNGKLSKRDGDKLGFPVFPLEWKTEEGVSSGYREKGFFPEAVVNFLALLGWNDGTDKELFSLEELVEAFDLNRVHKAGAKFDPEKNKWFNHQYLIKQNDADLAKSFSTILEEKGFSTPLEVTTRIVSLIKERAHFVSEFWDLTDFFFQAPSSYDEKASKNWKEETPALMKELISVLENIEDFTSANIETIVKEWLTKNEIGMGKVMQPFRLSLVGALKGPHLFDIVEIIGKEETVSRIQKAISAL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZEB1_CHICK
Sequence: MADGPRCKRRKQANPRRNNVTNYNNVIEANSDSDDEDKLHIVEEESITDAADCDASVPEDDLPTDHTVLPENSEREGSTNSCWEDEGKETKEILGPEAQSDEVGCTVKEDECDSDAENEQNHDPNVEEFLQQEDTAVIYPEAPEEDQRQGTPEASGQDENGTPDAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFSCSLCSYTFAYRTQLDRHMTSHKSGRDQRHVTQSSGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLMPVKGRARSGLKTSQCSSPSLSASPGSPARPQIRQKIENKPLQEQLPVNQIKTEPVDYEFKPIVVASGINCSTPLQNGVFSGGSPLQATSSPQGVVQAVVLPTVGLVSPISINLSDIQNVLKVAVDGNVIRQVLENNHANLASKEQETISNASIQQAGHSLISAISLPLVDQDGTTKIIINYSLEQPSQLQVVPQNLKKEHSVPTNSCKNEKLPEDLTVKSEKDKNFEGETNDSTCLLCDDCPGDLNALQELKHYETKNPPQLPQSSGTEAEKPSSPAPSETGENNLSPGQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQAGQISVQSSGPSSPEQVKISSPTDNDDQAATTNESEPQNSTNNSQNPANTSKSQTSSGGSTQNGSRSSTPSPSPLNLSSSRNSQGYTYTAEGVQEEPQMEPLDLSLPKQHGELLERSTITSVYQNSVYSVQEEPLNLTCAKKEPQKDNSITDSDPIVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYSTTVSPAVQETPPKQTQANGSQDERQDTSSEGVSNVEDQNDSDSTPPKKKMRKTENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEERDSTEQEEVGQEVLSSEHAGARASPSQIDSDERESLTREEEEDSEKEEEEEEEKDVEGLQEEKECRKLQDVEEEEEVEEEEEEEEGKTEGNKNDDVVNRASNAEPEVIQSNGQVSEEKTNKA
What is the function of this protein?
Acts as a transcriptional repressor.  Positively regulates neuronal differentiation.  Represses transcription by binding to the E box-containing promoter (By similarity).  Binds to delta 1-crystallin enhancer core and represses lens-specific transcription.  It binds as well many other non-lens specific DNA sequences.
What are the official names of this protein?
Zinc finger E-box-binding homeobox 1, Delta EF1, Delta-crystallin enhancer-binding factor, Transcription factor 8, TCF-8.
What is the protein family that this protein belongs to?
Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GARL_SALA4
Sequence: MNNAIFPNKFKAALAAQQVQIGCWSALASPITTEVLGLAGFDWLVLDGEHAPNDVTTLIPQLMALKGSASAPVVRVPTNEPVIIKRMLDIGFYNFLIPFVETQEEAARAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQQTIQHIFARAKAHGKPCGILAPVEADARRYLEWGATFVAVGSDLGAFRASTQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: WDR55_MOUSE
Sequence: MDPTCEESPAEDSNNEEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHILDVEQGQLERRISKAHSAPINSVLLVDENALVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCIVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEALALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEDAKAPEEVVRESDDDDDDSD
What is the function of this protein?
Nucleolar protein that acts as a modulator of rRNA synthesis.  Plays a central role during organogenesis.
What are the official names of this protein?
WD repeat-containing protein 55.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm.
Protein: HPRK_CALBD
Sequence: MFYTTVGKIIKELNLECLTEISGIEERKIKDMNLNRPALQLMGFFEYFDEQRVQIIGISEMAYLKTMTPSQRRDAIERLFQRNIPCVIITSNQEPFEEFLEFSKKYGVPLLRTQEVTTRFMTNLSTFLTHELAPRITRHGTLVNVYGEGVLMLGESGVGKSETALELVKRGHILVADDAVEIRKVSEKTLVGEAPEIIRHLIEIRGIGILDVKNLFGVGCVKESERIDLVIQLETWKQGKEYERLGLHDQYIEILGIKVPTLVIPVRPGRNLAIIVEVAAMNNRQKKMGYNAAKALTERLQKQMSRGNGAE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: PATE2_MOUSE
Sequence: MFVLVMICLFCQYWGVLNELEEEDRGLLCYKCKKYHLGLCYGIMTSCVPNHRQTCAAENFYILTKKGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSNYCNLPMGL
What are the official names of this protein?
Prostate and testis expressed protein 2, PATE-like protein M, PATE-M.
What is the protein family that this protein belongs to?
Belongs to the PATE family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANC_CUPPJ
Sequence: MKVISSIQELRDQLRGQNRVAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQSEGVYVLFAPTERDMYPEPQEYRVDPPHDLGDILEGEFRPGFFKGVCTVVMKLFTAAQPRVAVFGKKDYQQLMIVRRMVHQFALPIEIVPAETVRAEDGLALSSRNRYLTEAERAEAPMLYRTLHDVRDTVLGSDRAATRLATVEADACATLAQRGWKPDYVSIRKRSNLQAPTPEEFAAGEPLVVLTAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGK1_XENTR
Sequence: MRTKNEKSPLKAFMKQRRMGLNDFIQKIATNSSYACKHSEVQSILNISPPQEPELLNENSSPPPSPSQQINLGPSSNPHAKPSDFQFLKIIGKGSFGKVLLARHNADEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTTSRLYFILDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGAKNDFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQSPDSILITASIKEAAEAFMGFSYAPPMESYL
What is the function of this protein?
Protein kinase that may play an important role in cellular stress response (By similarity).  Plays an important role in activating certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion.
What are the official names of this protein?
Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum.
Protein: ACLL_ASPOR
Sequence: MLFSLGPLTIVYGLVIFVVAKTIYNLYLHPLRSYPGPLLARATRWYYSYYVKIGLLPQKTKELHDQYGPCVRIAPDELSYNTAEAWEDICGHRTGQRTESFEKDLTFFPPAPNGVDSIVRIDDVHRRFRRLLSHPMSDKALGSQQEIITGYVDQLIHELRQRSERSEVVDMVRWFNFTSFDILGDLAFGESFGCLGSGLMHPWIELIFTSIKSVMDMQIIRRIPGLFSLILTIAGLQQKQDLQEQFMFCQKKARERYTKETTRPDFMTYILRATEEKGMTPEEIEANAQILIMAGSETTASALSGTLFYLLKNSMAMQKLRQEIHATFQAEAEITMRSTQSMEYLHAVLQEAMRVYPPVPCTFPRTTPPGGAMVCGRFVPGGYIVGVNQLAAMTSEKNFKDPLKFIPERWCGDERYQEDSRKAYQPFSYGPRNCLGKNLAYAEMRLVLTRLLWNFEFDLLEESKDWHAKQKVWMMWDKGDLKVRLKPLRH
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).  The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411).  One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411).  After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411).  In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411).  Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
What are the official names of this protein?
Cytochrome P450 monooxygenase aclL, Aspirochlorine biosynthesis protein L.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.