PharMolix/UniProtQA huggingface dataset:
Protein: RL14_RICBR
Sequence: MIQMQSILEVADNSGAKKVMCIKVLGGSHHMVAKLGDVIVVSIKEAIPGGKVKKGDVYKGVIVRTKTGVVRADGSTIKFDKNALVLLNKQDEPIGTRVFGPVTRELRAKKYVRIMSLAEEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: KHDR3_RAT
Sequence: MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEAKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEDIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRTRGVTTPAITRGRGGVTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYSTAYDDQSYDSYDNSYSTPAQSGADYYDYGHGLGEEAYDSYGQEDWTNSRHKAPSARTAKGVYREQPYGRY
What is the function of this protein?
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion (PubMed:11118435).  Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro.  Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides.  Binds poly(A).  RNA-binding abilities are down-regulated by tyrosine kinase PTK6 (By similarity).  Involved in splice site selection of vascular endothelial growth factor.  In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (PubMed:11118435).  Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members.  Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity.  May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing.  Can bind FABP9 mRNA (By similarity).  May play a role as a negative regulator of cell growth.  Inhibits cell proliferation (By similarity).
What are the official names of this protein?
KH domain-containing, RNA-binding, signal transduction-associated protein 3, Sam68-like mammalian protein 2, SLM-2, rSLM-2.
What is the protein family that this protein belongs to?
Belongs to the KHDRBS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURI_BORBU
Sequence: MKNFKEVIIIFDSGIGGLSYFKYIKSRIGGCQYVYVADNKNFPYGEKSPEYLLEAVLFLIEKLKKIYNIGALVLACNTISVSVYNKLNFVFPVVYTLPDVSSVSDLVLKRVLLIATNTTLESKFVKDQVNIHNDLIVKAAGELVNFVEYGENYKKYALRCLEALKFEVVNTGREIVFLGCTHYLHLKVMIEDFLKIPVYENRELVVKNLIRSMNFSEHKGNYYKNDFDFVDDEFYLTENKNLTFYQNFCKKYNLRFKGMIV
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: TIG_CHLTE
Sequence: MQKNITNVSEIAQELEIILTAEEYQPEYDQQLEEARKSVRIKGFRQGHVPVGMLKRIIGPSIEAEVAEKMASKYFAAIAEEEKINPASRAQIESYNYEDGKLTIKISYEIHPEFELKDFSEYTFTQAEYTISDEDVDREIKLILRGHGTMVTSEDAAAEGDTVIGDVTKLDADGADIEGSKNENHHFNLEYLPADNPFRMALEGKKAGDVVDVTVKPKEEGGETNRFRIEIKEVKHLELPELDDELVKEISQQRFEKVEDFRNDIRLQLQAHFSDKSEYDLLEAISSKLIEEHPVPTPSAMVAHFQNILLENAKRQVGGQFPKGFDEREFFNAMKPNAEKHARWLLISQKIAKENNLEVTDEDIKAFAEKEAEKEPSLTVDQLLNTYLSTEFKDYIIDTILKEKIYDVIKSKVTITKEATPVPAHN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: MNME_JANSC
Sequence: MQTIFAQATARGKAGVAIIRISGPDAFEVGRCLLGSLPDAGRFALRDVRTPLGELLDRGLVLVFKAPASFTGEDTVELQLHGSVAVVRAVEGAIRSTGLARLADAGEFTQRALLNDMLDLTQVEGLGRLIDSETEAQRKVAQASFEGGLSDKAERWRHLMIRAAALLEASIDFVDEDVPVDVVPEVQSILMGLDTDLAKEVTGAVVAERLHDGFEVAILGAPNAGKSTLLNVLADREIAITSDVPGTTRDVIEARLDVSGLPVTFLDTAGIRDTVDVIEKIGVQRAIDRALAADVRILLEIDDWILPDVLSDTIDFRYRAKADLSDGEGISGRTGVGIDRLLTDIEGVLSEKMSAVRSAVTDRQRGGIEAARVSLDAGVTVLSGTAELELAAEHIRHAQRSLDSVIGRVDVENLLGEIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD320_MOUSE
Sequence: MARGGAGRAVALGLVLRLLFGLRTGLEAAPAPAHTRVQVSGSRADSCPTDTFQCLTSGYCVPLSWRCDGDQDCSDGSDEEDCRIESCAQNGQCQPQSALPCSCDNISGCSDVSDKNLNCSRPPCQESELHCILDDVCIPHTWRCDGHPDCLDSSDELSCDTDTEIDKIFQEENATTTRISTTMENETSFRNVTFTSAGDSSRNPSAYGVIAAAGVLSAILVSATLLILLRLRGQGYLPPPGLLVAVKESLLLSERKTSLI
What is the function of this protein?
Receptor for transcobalamin saturated with cobalamin (TCbl).  Plays an important role in cobalamin uptake.  Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells.  Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation.  Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC).  CD320 augments the proliferation of PC precursors generated by IL-10.
What are the official names of this protein?
CD320 antigen, Transcobalamin receptor, TCblR.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SYL_BIFLO
Sequence: MSDNEKSTQTEEPNFRYNAALAQDIENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGYLASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMGLSFDNRRTFATIDPGYVRWTQWIFSRIYDSWYDEDATNPSGSKGSARPIAELVAKFESGEKAIPGHESDGKQWSDLTDAEQQDILNDFRLAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADLDGINWPEKVKLMQRNWIGESHGASVHFIVATADGDKDMEIYTTRPDTLFGTTFAVVSPEHHLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNEAGEKTGLFTGLYATNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDDLANYEGKAPFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTVSYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESNPEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEFDYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQGMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDYMYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTPDEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIAPHICEEMWSKLGHAESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPADLEKQALAAVADRLGGKEPRKVIVKAPKIVSIVPAE
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_BACFN
Sequence: MKNEPTYSLLNAINYPKDLRQLSVDQLPEVCEELRQDIIKELSCNPGHFAASLGVVELTVALHYVYNTPYDRIVWDVGHQAYGHKILTGRREAFSTNRKLGGIRPFPSPEESEYDTFTCGHASNSISAALGMAVAAERKGEKDRHVVAVIGDGSMSGGLAFEGLNNASSTANNLLIILNDNDMAIDRSVGGMKQYLFNLTTSNRYNQLRFKTSRLLFKMGLLNEERRKALIRLGNSLKSLAAQQQNIFEGMNIRYFGPIDGHDVKNIARILHDIKDMQGPKILHLHTIKGKGFGPAEKQATIWHAPGKFDPVTGKRIVANTDGMPPLFQDVFGHTLVELAEKNKRIMGVTPAMPSGCSMNMLMDRMPDRAFDVGIAEGHAVTFSGGMAKDGLLPFCNIYSSFMQRAYDNIIHDVAIQKLNVVFCLDRAGLVGEDGPTHHGVFDMAYLRPIPNLTISSPMDEHELRRLMYTAQLPDKGPFAIRYPRGRGSLVDWECPLEEIPVGKGRKLKDGNDLAVITIGPIGKLAARAIERAEADTGISVAHYDLRFLKPLDEELLHEVGKKFRHIVTIEDGIIKGGMGCAILEFMADNGYYPEIRRIGVPDQFIEHGSVQQLYHLCGMDEEGIYKVITKNKLRMDAPVESCMATHS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: SYC_RICAH
Sequence: MQIQLHLYNTLSRTKEVFNPQDQANIKMYVCGPTVYDNPHIGNSRSVVVYDLLYRIVIKIFGSRAVKYVRNITDVDDKIIDRAELLGITINELTDKVTQEFHTNMAYLGCMLPNIEPKATEHIDVMIEIIERLIAKDHAYITDNHVYFDVLSAPNYTELSNRNLEEMFEGVRIEKSKTKNHPQDFVLWKPAKPNESTNMNFESPWGFGRPGWHIECSAMSYKYLGENFDIHGGGADLVFPHHTNEIAQSRCAFPDSTYAKYWVHNGFLTVNGEKMSKSLGNFITVRDLMDKDISGEVVRLFLLSSHYRRPLDYNDKAIEDAKKTLDYWYRAIENINVQKIDLPHNFMQSLLDDMNTPLAVKIINDYAKGVFIAKTEKERQLNASVIITCANFIGLMNQTPHEWFNSGVDSLYINELVNKRLEAKKQKNWLLADQIRNQLLEGKIILEDKSDGTTIWRKE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGAL6_ORYSJ
Sequence: MAAATVGVLLRLLLLPVVVVVSLLVGASRAANVTYDHRAVVIDGVRRVLVSGSIHYPRSTPDMWPGLIQKSKDGGLDVIETYVFWDIHEAVRGQYDFEGRKDLVRFVKAVADAGLYVHLRIGPYVCAEWNYGGFPVWLHFVPGIKFRTDNEAFKAEMQRFTEKVVDTMKGAGLYASQGGPIILSQIENEYGNIDSAYGAAGKAYMRWAAGMAVSLDTGVPWVMCQQSDAPDPLINTCNGFYCDQFTPNSKSKPKMWTENWSGWFLSFGGAVPYRPAEDLAFAVARFYQRGGTFQNYYMYHGGTNFGRSTGGPFIATSYDYDAPIDEYGMVRQPKWGHLRDVHKAIKLCEPALIAAEPSYSSLGQNTEATVYQTADNSICAAFLANVDAQSDKTVKFNGNTYKLPAWSVSILPDCKNVVLNTAQINSQVTTSEMRSLGSSIQDTDDSLITPELATAGWSYAIEPVGITKENALTKPGLMEQINTTADASDFLWYSTSIVVKGDEPYLNGSQSNLLVNSLGHVLQIYINGKLAGSAKGSASSSLISLQTPVTLVPGKNKIDLLSTTVGLSNYGAFFDLVGAGVTGPVKLSGPNGALNLSSTDWTYQIGLRGEDLHLYNPSEASPEWVSDNAYPTNQPLIWYKTKFTAPAGDDPVAIDFTGMGKGEAWVNGQSIGRYWPTNLAPQSGCVNSCNYRGAYSSNKCLKKCGQPSQTLYHVPRSFLQPGSNDLVLFEQFGGDPSMISFTTRQTSSICAHVSEMHPAQIDSWISPQQTSQTQGPALRLECPREGQVISNIKFASFGTPSGTCGNYNHGECSSSQALAVVQEACVGMTNCSVPVSSNNFGDPCSGVTKSLVVEAACS
What is the function of this protein?
Releases galactose by hydrolysis of plant cell wall galactose-containing polysaccharides such as galacto-xyloglucan, pectic galactan and galactan (in vitro).
What are the official names of this protein?
Beta-galactosidase 6, Lactase 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: THSB_METTH
Sequence: MAQGQQPILVLPEGTSRYLGRDAQRMNILAGKILAETVRTTLGPKGMDKMLVDSLGDIVVTNDGVTILKEMDIEHPAAKMLVEVAKTQEDEVGDGTTTAVIIAGELLKKAENLLEMEIHPTIIAMGYRQAAEKAQEILDDIAIDASDRDTLMKVAMTAMTGKGTEKAREPLAELIVDAVKQVEEDGEVEKDHIKIEKKEGAAVDDSTLVQGVIIDKERVHPGMPKKVENAKIALLNCPIEVKETEVDAEIRITDPSQMQAFIEQEEQMIRDMVNSIVDTGANVLFCQKGIDDLAQHYLAKAGVLAVRRVKKSDMEKLSKATGANIVTNIEDLSPEDLGEAGVVSEKKISGEEMIFVEECKEPKAVTILVRGSTEHVVSEVERAIEDAIGVVAATVEDGKVVAGGGAPEIEIAKRLKDYADSISGREQLAVSAFAEALEIVPKTLAENAGLDSIDVLVDLRAAHEESTYMGIDVFDGKIVDMKEAGVIEPHRVKKQAIQSAAEAAEMILRIDDVIAASSSGSSEEGMEEMGGMGGMPPM
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit beta, Chaperonin subunit beta, Thermosome subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: ODBB_PSEPU
Sequence: MATTTMTMIQALRSAMDVMLERDDNVVVYGQDVGYFGGVFRCTEGLQTKYGKSRVFDAPISESGIVGTAVGMGAYGLRPVVEIQFADYFYPASDQIVSEMARLRYRSAGEFIAPLTLRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLIASIECDDPVIFLEPKRLYNGPFDGHHDRPVTPWSKHPHSAVPDGYYTVPLDKAAITRPGNDVSVLTYGTTVYVAQVAAEESGVDAEVIDLRSLWPLDLDTIVESVKKTGRCVVVHEATRTCGFGAELVSLVQEHCFHHLEAPIERVTGWDTPYPHAQEWAYFPGPSRVGAALKKVMEV
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
2-oxoisovalerate dehydrogenase subunit beta, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDH E1-beta.
Protein: SYV_GLOVI
Sequence: MARTLPSQYDPFDAEPRWQRFWEEHRFFSPAADGPGKPFSLVLPPPNVTGSLHMGHALCFTLPDVVVRYRRMKGFKTLWLPGTDHASIAVHTVLEKQLRQEGKTRFDLGREAFLERAWAWKERSQDTIRGQLRRLGLSLDWTRESFTLDEKRNRAVVKVFVDLHRKGLIYRGKYLVNWCPASQTAVSDLEVDDKEEKGHLWQLRYPVADSDEFLVVATTRPETMLGDTGVAVHPEDPRYKHLIGREAELPILGRRIVIVGDEAVDREFGTGAVKVTPAHDPNDFEIGKRHGLPMINLLNPNGTYNENAGPYAGLDRFVVRKQVVARAAAEGWLVGIEDHVHNVPYSERGGVPIEPYLSDQWFLDVSGMATRVLEAFDSQNQPAFVPERWGKVYRDWLVRIRPWNISRQLWWGHRIPAWFVAGSEGEYVVAHDEAEAFAVARERYGPDVQLQRDQDVLDTWFSSSLWPFTTLGWPDQTEDLGVFYPNALMSTGFDIIFFWVARMAMMAGEFTGQIPFETVYINGLVRDEKGQKMSKTKGNGIDPIEMMDKYGTDALRYTLVREVTGAGQDVRFDYNRKTGESGAVDASKRFANKIWNASRFVLMNLDELTPAALGAADPGSLTLEDRWILGRLGQTARQIDELLGRYALGEAARSLYEFIWDDFCDWYVELAKPRLEALETRRGAQQVLAAVLDRTLRLLHPWMPHLSEEIWQLLHQPLEVASICVQPFPTGTDLPAEPPAEFALMQQIVRTIRNLRAFAQVPPLRTLPAVRLASRNAEERAAIDATRQAIAHLGRVEQLPLEEVADEHLKQVAVGVAGTVQVMLPLGGLVDVAALAGKLRRSLEKLDKESGVLAARLDNASYLANAPAELVTESRAKLAEQRAQAAILAEQLARLEN
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_PSYIN
Sequence: MLRGANAINLDTKGRIAIPTRYRDWLGDTCQGQFVCTIDIQSPCLLIYPLNEWLLIETKLRALSSTNPQERRLQRLILGYATESELDKSGRALIAPTLRQHAKLQKKVMLVGQLNKFELWDEDMWNQQIKNDLEDGLPTGIELSSGLREFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YBEY_THET8
Sequence: MVEVVRNKRPPRGLVPRLRRALAALMEELGVGDKGVTVILTGDRRLRALKREWWGEDEATDVLSFPHYEPGDPFVPPHLGDIWISLDTARRQAEARGASLEEEVLVLAAHGLWHLLGHDHQKEEDWEGFRRVQERILAL
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_STRU0
Sequence: MIIKVPATSANLGPGFDSVGIAVTKYLEIEVLEERDDWYVEHTLENVPSDHHNLLIQTALRLAPDIKPHHILMRSDIPLARGLGSSSSVIVAGIELANQLAKLELSMDRKFAIATEIEGHPDNVAPAIFGQLVIASQLDNQLDYIRAPFPEASLLAFIPNYELKTSDSRDALPKHLSYKQAVAASSIANLAIAALLKGDMEKAGRAIENDLFHELYRQRLVKEFHSIKQISKKSGAYATYLSGAGPTVMILCPHEKVEGIFQELTDLSLDGLLERLQIDEKGLQVLF
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBLD_BOVIN
Sequence: MKLPIFIADAFTTKAFRGNPAAVCLLENKLDEDLHQKIAKEMNLSETAFIRKLHPNDNFTQSSCFGLRWFTPQNEVPLCGHATLASAAVLFHKIKNVHSTLTFVTMSGELKARKEEDGIVLDLPLYPAHPQKLHEVEDLIKTAIGDTLVQDVRYSPDTKKLLVRLSDTYNRSFLESLTVNTENLLQVETTGKVKGLILTLKGEPGGQTQAFDFYSRYFAPWYGVAEDPVTGSAHTVLSSYWSEQLGKKDLHAFQCSNRGGELTISLRSDGRVDIKGGAALVLEGTLTA
What are the official names of this protein?
Phenazine biosynthesis-like domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the PhzF family.
Protein: GLKA_PYRHO
Sequence: MITMTNWESLYEKALDKVEASIRKVRGVLLAYNTNIDAIKYLKREDLEKRIEKVGKEEVLRYSEELPKEIETIPQLLGSILWSIKRGKAAELLVVSREVREYMRKWGWDELRMGGQVGIMANLLGGVYGIPVIAHVPQLSELQASLFLDGPIYVPTFERGELRLIHPREFRKGEEDCIHYIYEFPRNFKVLDFEAPRENRFIGAADDYNPILYVREEWIERFEEIAKRSELAIISGLHPLTQENHGKPIKLVREHLKILNDLGIRAHLEFAFTPDEVVRLEIVKLLKHFYSVGLNEVELASVVSVMGEKELAERIISKDPADPIAVIEGLLKLIKETGVKRIHFHTYGYYLALTREKGEHVRDALLFSALAAATKAMKGNIEKLSDIREGLAVPIGEQGLEVEKILEKEFSLRDGIGSIEDYQLTFIPTKVVKKPKSTVGIGDTISSSAFVSEFSLH
What is the function of this protein?
Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
What are the official names of this protein?
ADP-dependent glucose/glucosamine kinase, ADP-dependent glucokinase, ADP-GK, ADPGK, Glucosamine kinase, GlcN kinase.
What is the protein family that this protein belongs to?
Belongs to the ADP-dependent glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAP30_ANOGA
Sequence: MMNNNGFSTGEEDSRGPADQICCLLDDGERCRKQAGNASYSKRIQKTVTQRRLKLSIDSHARHIYICDFHKARIQCARTKRRRRDSEDDSNETDTDLPEVDLYQLQVNTLRRYKRFYKVSTRPSSNKAQLSETIMKHFKTIPIKEKEILTYFIYMVKSNSNKLDQKNNASAEAT
What is the function of this protein?
Required for the function of the class 1 Sin3-histone deacetylase complex (HDAC).
What are the official names of this protein?
Histone deacetylase complex subunit SAP30 homolog.
What is the protein family that this protein belongs to?
Belongs to the SAP30 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNC_DESRM
Sequence: MSKQDEQANRLKTRLGFKWHNPTLLIQALTHSSCVHENRGHGLCHNQRLEFLGDAVLELIISEHLYKMFPDRTEGELTKMRASSVCEPSLAKVARGLDLGRCLRMGRGEERSGGRERPSILADAFEALLGAIYLDQGLEISRHFVLNCLSSIIDDVVAGRLDRDYKTELQEILQQSSPDPLTYTIMDESGPDHDKTFTAGVIYKGKVIGKGSGHSKKEAEQQAAKDAFQHLEGMGKSGHKSAGPIR
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_PSEE4
Sequence: MAFLALGINHKTASVDVRERVAFTPEQLVDALQQLCRLTASREAAILSTCNRSELYIEQDHIAADAVLQWLADYHQLSLDELRASAYIHEEHDAVRHMMRVASGLDSLVLGEPQILGQMKSAYAVAREAGTVGPLLGRLFQATFSAAKQVRTDTAIGENPVSVAFAAVSLAKQIFSDLGRSQALLIGAGETITLVARHLHEQGVRRIVVANRTLERASILAEQFGAHAVLLADIPQELANSDIVISSTASQLPILGKGAVESALKQRRHKPIFMVDIAVPRDIEPQVGELDDVYLYTVDDLHEVVAENLKSRQGAAQAAEELVSAGADDFMVRLRELAAVDVLKAYRQQSERLRDEELQKALRLLGNGGNPEDVLMQLARGLTNKLLHAPSVQLKKLSAEGRLDALAMAQELFALHEGSTDKTPQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: UL26_HCMVA
Sequence: MYAVFGLTRSEVTPHEAAAARYKHRGVIDRQGAAMTSRRAPDGGLNLDDFMRRQRGRHLDLPYPRGYTLFVCDVEETILTPRDVEYWKLLVVTQGQLRVIGTIGLANLFSWDRSVAGVAADGSVLCYEISRENFVVRAADSLPQLLERGLLHSYFEDVERAAQGRLRHGNRSGLRRDADGQVIRESACYVSRVLLRHRVTPGKQEITDAMFEAGNVPSALLP
What is the function of this protein?
Plays a role in the inhibition of host NF-kappa-B.  This inhibition affects both the canonical and the non-canonical pathways.  Blocks the induction of host IKK phosphorylation.  May also influence the normal phosphorylation state of several tegument proteins including pp28 in virions.
What are the official names of this protein?
Tegument protein UL26.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Note=Also found in dense bodies.
Protein: HBB_ODORO
Sequence: VHLTADEKAAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSPDAVMGNPKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DNA2_XENTR
Sequence: MEPVSAECQLPPEDDLLEMMMEQSFTEPEEKSKDKSTRKIIPKTKLCRGLNNRYCVLNVKEVYAQGEEKHLTITASQEGDDLELCILKDDWVALHIKPGDIIHLEGNCAFDNTWTISRDTGYLILYPDLLISGTSIANGIRCLRRSVLSEKFKVCDKGSRQMLIGTMLHDIFQRATTRGFTDSVLQELAHHTVHGPKYLKEMYQLKLNQTDVMGEVQEYLPSFAKWAIDFMTHPLNQHQINVTRPTAGDPTEATKVSEFLDIEENIWSPRFGLKGKIDVTARVKIHQKSKSHLKIMPLELKTGKESNSIEHRSQVVLYTLLSQERREDPEAGLLLYLKTGNMYSVPGNRLDRRELLKIRNELSYYLTNVVHKSDNGSKEITLASLPALIADRQACKFCSQMRNCALYSRSVEQQIENCYIPAEMIPVVQKETEHLNKDHLQYFRLWYLMCTLEGNSKDSKMGRKNIWMMSSSEREEDGQCIGNLIRTGPVQTISDGQHLHSFQRKSGTVPATNLMSGDRVVVSGEDKFLALSSGYIKEVKHNNITCILDRSLGKLPEDLLFRLDHEEGGGGLESHLGNLSRLMENSPVSDKLRKLIIDFSKPNFVQHLSSVLPSDAKDIVANILKGLNKPQKQAMKRVLLSKDYTLIVGMPGTGKTTTICTLVSTLHLKTCTSCLVDDHREAAGTHRSHRHSKGTVNLGKQKRQHRVTSTTSSTSAKCRSKTEPAVSAENKKLQKLISGSHVCIMVNGHKTFSQNNYIIFFDNILLLKKLPLHYMCAFALIHHQCFKGCVKSVSLVRELGMSESLFKRLERNQEAVVQLTVQYRMNSQIMALSNKLVYEGRLECASDRVSNAVVKLPHIKTLLLELEFRESQESMWIKDVLEPSNPVCFLNTEKIPALETEEKGGISNWIEAKLVFCLTKLFLKAGCRPSDIGIIAPYRQQLKVISNYFNSLSASAVEVNTVDKYQGRDKSVIIVSFVRSNIDGKLGDLLKDWRRLNVALTRAKHKLIMLGCVPTLSRFLCLEQLICHLKSKNHIYDLPAGAHEHMPV
What is the function of this protein?
Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion.  Involved in Okazaki fragments processing by cleaving long flaps that escape fen1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit dna2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1.  Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by the presence of RPA.  Also involved in DNA replication checkpoint independently of Okazaki fragments processing.  Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5'-3' helicase and endonuclease activities.  While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is subject to debate.  According to various reports, the helicase activity is weak and its function remains largely unclear.  Helicase activity may promote the motion of dna2 on the flap, helping the nuclease function (By similarity).
What are the official names of this protein?
DNA replication ATP-dependent helicase/nuclease DNA2, DNA replication ATP-dependent helicase-like homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.