PharMolix/UniProtQA huggingface dataset:
Protein: GYRB_MYCS2
Sequence: MAAQKNNAPKEYGADSITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGFATRVDVKIHADGSVEVRDDGRGIPVEMHATGMPTIDVVMTQLHAGGKFDGETYAVSGGLHGVGVSVVNALSTRLEATVLRDGYEWFQYYDRSVPGKLKQGGETKETGTTIRFWADPEIFETTDYNFETVARRLQEMAFLNKGLTIELTDERVTAEEVVDDVVKDTAEAPKTADEKAAEATGPSKVKHRVFHYPGGLVDYVKHINRTKTPIQQSIIDFDGKGPGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRAALTSVVNRYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVAEPQFEGQTKTKLGNTEVKSFVQKICNEQLQHWFEANPAEAKTVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPSKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQSIITALGTGIHDEFDISKLRYHKIVLMADADVDGQHISTLLLTLLFRFMKPLVENGHIFLAQPPLYKLKWQRSEPEFAYSDRERDGLLEAGRAAGKKINVDDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVEARRSFITRNAKDVRFLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner (PubMed:8878580) to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFA_AEDAE
Sequence: MKSITVICFLALCTVAITSAYPQEPVLADEARPFANSLFDELPEETYQAAVENFRLKRATCDLLSGFGVGDSACAAHCIARGNRGGYCNSKKVCVCRN
What is the function of this protein?
Antibacterial peptide mostly active against Gram-positive bacteria.  Has activity against the bacteria Gram-negative E. cloacae beta12.
What are the official names of this protein?
Defensin-A, AaDef.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPB_HAHCH
Sequence: MTRIAIVGASGRMGKVLVEAVCDNPDASLGAASVRVGSSLVGADAGEIAGLGKKGVACVDDLAQVMDDFDVIIDFTSPETTLELLALCRKEGKAIVIGTTGFSDQQKTLLAEAAQDCPVVFAPNMSVGVNLLLNILALTAKTLGDDYDVEVIEAHHRFKKDAPSGTALRLGEVVAEAMGRNLNECAVYGREGITGERDKKTIGFETIRAGDIVGEHTVMFATMGERIEITHKASSRMTFAKGAVKAALWLHGVAPGLYDMQDVLGLK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTA_ALIF1
Sequence: MNVTQQSEKEAVIKLTGISKSFDGKEVISNFDLDVNHGEFLTILGPSGCGKTTVLRMIAGFETADAGTILLDSTDVTSVPAEQRHVNTVFQSYALFPHMTVFENVAFGLRMQKVAESEIEPRVTEALQMVRLAQMANRKPHQLSGGQQQRIAIARAVVNKPKVLLLDESLSALDYKLRKQMQIELKQLQRQLGITFIFVTHDQEEALSMSDRIIVMRDGVIEQDGTPREIYEEPKNLFVARFIGEINVFAATVQERLDEKRIKAEIEDTSAIVYCDLDVAPGDKVKVLLRPEDLRLEEIKESDNKGITGYVRERTYKGMTLDSVLELDSGMRVMISEFFNEDDPDVDHSLGQKVAITWVESWEVVLADEQEV
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSD_CHLPD
Sequence: MPTSYGYTTLLKTTLVCCLLTALVSIFLPALLPLTATGSAAVIIFTLYFFRDPERRIPLDQQVIVAPADGKILLIQPLDHAFTGNDSTLVSIFMSPFNVHVNRIPLDGTIVHLRYVPGKFLMAFDNRSMESNEKMEIGIDNGSLRVLFIQVAGFLARRIVCPLHRNESVLSGKRFGMIKFGSRVDMILPAAVKIMVQSGQKTCAGETIIGRY
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TM104_DICDI
Sequence: MAGGPSDGSTYSKKTAFVYIFNLIVGVGALALPYGFSKAGLVLGLLFLAAIGFLAFITATWLIEGLSIANFILVNKKEERIIGDDDNENYQKPPTENDSLINSEYSDNKILQSNAEDRNLLEPSGGSSSSDNEQFEIKKRVEVGEMSKMFLGNIGYKVFYGVLIIYLFGDLSIYAATVPTTLANVTGGWGKFTDHTVYYFYLFLFACFVGPFSLFNFQKTKYLQFATLITRNVAFLLMIILSIIFIAQGNGASIKQVPIFEISELASIFGVSIYSFMTHHSIPGFLTPISKKDRLFTLMGLDFILVFIAYGTLCVVSLFAFGAVTNPTCATASTSIHTFIPCQIQSLYIYNFTSYNSKFVSDFLSLFPVFTLSTNYILISITLRNNLLQLITWKQDKISSKVRNVVFSLTSSLIPVGVAFCTRNVSLLVNITGSYAGLGIMFVMPALISFYSNKILIEQYHISNPKKSPFSNKFFYLLILLISVICLILATWKIIITYK
What are the official names of this protein?
Transmembrane protein 104 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM104 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECR_BACC7
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAVRLAFFVLDMKEDDVLGFAKALVNAKRDLAYCSVCGHITDRDPCYICNDSHRDQSVVCVVQEPKDVIAMEKMKEYQGVYHVLRGAISPMEGIGPEDINIPQLLKRLHDETVQEVILATNPNIEGEATAMYISRLLKPTGIKVTRIAHGLPVGGDLEYADEVTLSKALEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: FENR_BEII9
Sequence: MGEAIVTDVVIVGAGPAGLFAVFELGLLDIKSHLIDILAKPGGQCAELYPEKPIYDIPGYPRVNGQELVDNLLAQIEPFHPTFHFGEMVERLEVLGTPEAPSFRVHTSGGEIFESKVVIVAAGGGSFQPKKPPIEGIEAFERKSVFYAVRKMEDFRDKHVVIVGGGDSALDWTLNLHPIAKRITLVHRRDDFRAAPHSVNSMRELVAAGHMDLRLGQIVSLRGEAGELSAVVLKGSDGEAEIACERLVPFFGLTMKLGPIADWGLNLHENLIPVDTEKFETNVSGIFAIGDINTYPGKLKLILSGFHEGALAAQKVHRYVYPDKRLSFQYTTSSSSLQKKLGVN
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: ZGPAT_BOVIN
Sequence: MDEESLQTALRTYDAQLQQVELALGAGLDPSELADLRQLQGDLKELIELTEASLVSVRKSKLLAALDGERPAQEDAEPLALQNAIAETAEVPVAPGAELETVPSRETGPGPTERGQEEDDGEDEEGGAALSGRKVNAPYYSAWGTLEYHNAMIVGTEEADDGSPGVRVLYLYPTHKSLKPCSFFLEGKCRFQENCRFSHGQVVSVDELRPFQDPDLSSLQAGSACLAKRQDGLWYPARITDVDSGYYTVKFDSLLLKETVVEGDSILPPLRTEPAGSSDSDGSDADDPSYARVVEPGAANPGTCSSAFAGWEVHTRGIGSRLLAKMGYEFGKGLGRHAEGRVEPVHAVVLPRGKSLDQCAEILQKRTRAGQAGVSKPPKCRSRGSGPGGRPPPRSVFDFLNEKLKGGAPGAPEVGAAPPGRSGKEVYHASRSTKRALSLRLLQTEEKIEQTQRAIRGIQEALARNAGRHSVTTAQLQEKLAGAQQQLGQLRAQEAGLQREQRKADTHKKMTEF
What is the function of this protein?
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence.  Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters.  Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration.  Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity).
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: UVRC_MYCVP
Sequence: MPDPSTYRPAPGSIPVEPGVYRFRDPHGRVIYVGKAKSLRSRLNSYFADLSGLAPRTRQMVMTAASVEWTVVSTEVEALQLEYNWIKEFDPRFNIRYRDDKSYPVLAVTLNEEYPRLKVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSNGVFKRHSQIDRPCLLGYIDKCAAPCVGRVSAEEHRRIVLDFCDFLAGKTDRLIREMEQQMNAAAEELDFERAARLRDNIGAMRRAMEKQTVVLGDGTDADVVAFADDELEAAVQVFHVRGGRVRGQRGWVIEKSGEPGESTPAYLVEQFLTQFYGDQAELGGAADEATNPVPRQVLVPVLPDTTEELETWLSQLRGSRVSLRVPQRGDKRALAETVKRNAEQALTQHKLKRAGDFTARSAALQSIQEALGLADAPLRIECVDISHVQGTDVVASLVVFEDGLPRKSDYRHFAIREAAGDGRSDDVASIAEVTRRRFHRHLRDAEAAPEGRPEQGPRASARPEQGPRASARPARFAYPPNLFVVDGGAPQVNAAAAVLDELGISDVAVIGLAKRLEEVWVPNLDGTAPDPVIFPRNSDGLYLLQRVRDEAHRFAISYHRSKRSKRMTASALDSVRGLGEHRRKALVTHFGSLARLKQASVDEITAVPGIGAATARAVLEALGADSGAAPTDIGNDQSRISG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_DEIGD
Sequence: MAKHPVPKKKTSKSKRDMRRSHHALVAPNLTECPQCHSKKLQHHICPSCGYYNGRQVLAV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: Y2677_LISMC
Sequence: MRGMGNMQGMMKQMQKMQKEMAKAQADLEAQEFTGTAGGGMVTVKATGKRVITDVVINEEVVDPEDIEMLQDLVLAATNDVLKQIEDTTSQTMGKFTQGLNIPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Lm4b_02677.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYP_ECOUT
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDRPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y543_RICFE
Sequence: MITKKDKPLNIYCPLVSIIIPVYNGANYMREAIDSALAQTYENIEIVVVNDGSKDNGETENVALSYGDKIRYFHKENGGCGSALNYGIKNMKGEYFSWLSHDDIYYPNKIEHQVNILNKLDNKDTIIYGGYELIDEKGSSLRYIKPDSVLPINKLNISLLPLLRGLIHGCSLLIPAKYFHEIGIFNEALPTTQDYDLWFKILRVAPIHFDESILIKSRFHSEQGSKKISNHNEECNVLWSSFLHELTEEEMIKMEDSPYLFLTRTATFLSNNTPYKKACDLANTMAKQVLHDTKVSVIIPVYNRINWAIEAIESVLIQTHKNFEILIIDDGSTDDISELTSICKKDKRIRYFHKKNEGPAAARNLGIKNAIGKYIAFLDSDDLFYKDKIEIQLKFMEENNFIFSHTSYQKINEKGKYIESVHSGFFSGNVFPQIIQTCPIAMPTVMGTLTLFQENLFPENIRSGEDCCLWISIASKNSIGGIDKELSKVRISGGTNTFMDPNKYSVGLINITSYVLNDPYLSKFSPFTINLLLAAVTQLRLLENKDYKKSNISFFNNNYVIQKIQTYCFVTKILILLTITSIRQEGIRATISRIQRWLRKHI
What are the official names of this protein?
Uncharacterized glycosyltransferase RF_0543.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: SYR_SYNAS
Sequence: MQIMIGSSIKHRLTMLVKNAVDGCVAEGLLAGGNFPPVEMEMTKDTVHGDYATNFAMVMASHARMNPRKIAEMISSHFRDGEQILEKTEIAGPGFINFFVRENVWAEQLKDIESLGNHYGSAETGRGKKVQVEFVSANPTGPLHIGHARGAVVGDVIANILGMSGYEIFREYYINDAGNQMNNLGKSVWYRYQELLGRSVEFPDTCYQGDYIREIAGDILKKDGDIHLTSNEDSNIRFFTDYAAGIILEEIKQDLKDFGIVFDKYFSERELYVNDGVARLLADLEEKGFIYRDDETLWFKTTDFGDDKDRVVVRKNGEPTYFAADIAYHKNKYERGFDSVIDIWGADHHGYIPRMHAGIQALGHSKDALRVVLVQLVNLLRDGKPVAMSTRSGEFVTMKEVVDEVGRDAARYNFLMRRSDSHLDFDLEVAKRQSNENPVYYVQYAHARICSILRMAKERGIELPSFENVEPQLLRIPEEIALIKTLTRFPEVVEGSARTLEPHRITFYLNDLAGLFHSYYNKYKVISDDEAMTRTRLFLVKCIQTVLKNALTLLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_LIMF3
Sequence: MSRLDQKTVANRYARAIFELAQEDGQLDQTYQELVSVRQVFLDNPSLAPLLAGVDLGIKEKQALVDQVKEGASKYVANLLQMAFDYRRMSDMVAIVDEFERRYDEKHKRVHAEVVTAVQLDETRRNQLRDNLAARLGAQEIVLNEKVDPTILGGVVVKTANQTLDGSIKTKIEQIRRLIVK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL5_SHEB8
Sequence: MAKLHDKYQETVVAELAKKFGYTSVMQVPRIEKITLNMGVGEAVADKKIMDHAVRDMTAIAGQKPVVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSAKAFDGRGNYAMGVREQIIFPEIDYDKIDKIRGMDIVITTTAKNDEEGRALLDAFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TMUB1_RAT
Sequence: MALIEGVGDEVTVLFSVLACLLVLALAWVSTHTTESTDPLPQSSGTTTPAQPSEAMTAIDSIREEAPGAESPSLRHRGPSAQPEPEAGVTASTPPDSPQEPLLLRLKFLNDSEQVARAWPQDTIGSLKRTQFPGREQQVRLIYQGQLLGDDTQTLGSLHLPPNCVLHCHVSTRVGPPHPPCPPGSEPGPSGLEIGSLLLPLLLLLLLLLWYCQIQYRPFFPLTATLGLAGFTLLLSLLAFAMYRP
What is the function of this protein?
May contribute to the regulation of translation during cell-cycle progression.  May contribute to the regulation of cell proliferation (By similarity).  May be involved in centrosome assembly.  Modulates stabilization and nucleolar localization of tumor suppressor CDKN2A and enhances association between CDKN2A and NPM1 (By similarity).
What are the official names of this protein?
Transmembrane and ubiquitin-like domain-containing protein 1, Hepatocyte odd protein shuttling protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Recycling endosome. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Nucleus, nucleolus. Note=Localized to neuronal soma and dendrites (PubMed:18665261). SUBCELLULAR LOCATION: [iHOPS]: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus, nucleolus. Nucleus. Note=iHOPS is proposed to be the shuttling form across different cellular compartments (By similarity). XPO1-dependent exported from the nucleus in dividing cells. Predominantly nuclear during growth arrest (PubMed:16014383).
Protein: RF2_BEUC1
Sequence: MATDFPAEISALRGTLEQITAVTDPDALRARIAELSEAAAAPDLWDDPDAAQKVTSRLSHTQSELERLDTLRSRIDDLETLVQLAAEEDDADTLAEAEAELTKIRTSMGELEVRTLLAGEYDSREAVVTIRSGAGGVDAADFAEMLLRMYLRWAERKGYPTQVLDTSYAEEAGLKSATFEVKVPYAFGTLSVEAGTHRLVRISPFDNQGRRQTSFAAVEVIPLIEQTDHIDIPETDIRIDVFRSSGPGGQSVNTTDSAVRITHLPTGIVVSMQNEKSQIQNRAAAMRVLQSRLLLAMQEEENAKKKELAGDVKASWGDQMRSYVLQPYQMVKDLRTEHEVGNPSAVFDGDIDDFIEAGIRWRRQQQTVRESATA
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_BACCN
Sequence: MIKVVFMGTPDFSVPVLRRLIEDGYDVVGVVTQPDRPVGRKKVMTPTPVKVEAEKHGIPVLQPLKIREQDEYEKVLALEPDLIVTAAFGQIIPKEILEAPKYGCINVHASLLPELRGGAPIHYAIMQGKEKTGITIMYMVEKLDAGDILTQVEVEIEERETTGSLFDKLSEAGAHLLSKTVPLLVQGKLEPIKQDEEKVTFAYNIKREQEKINWAKTGEEVYNHIRGLNPWPVAYTTLAGQVVKVWWGEKVPTANDAQPGTIVEIQEDGFIVVTGNETGIKITELQPAGKKRMSSSQFLRGAKLEIGMKLGEDA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SACB2_NEIMD
Sequence: MFILNNRKWRKLKRDPSAFFRDSKFNFLRYFSAKKFAKNFKNSSHIHKTNISKAQSNISSTLKENRKQDMLIPINFFNFEYIVKKLNNQNAIGVYILPSNLTLKPALCILESHKEDFLNKFLLTISSENLKLQYKFNGQIKNPKSVNEIWTDLFSIAHVDMKLSTDRTLSSSISQFWFRLEFCKEDKDFILFSTANRYSRKLWKHSIKNNQLFKEGIRNYSEISSLPYEEDHNFDIDLVFTWVNSEDKNWQELYKKYKPDFNSDATSTSRFLSRDELKFALRSWEMSGSFIRKIFIVSNCAPPAWLDLNNPKIQWVYHEEIMPQSALPTFSSHAIETSLHHIPGISNYFIYSNDDFLLTKPLNKDNFFYSNGIAKLRLEAWGNVNGECTEGEPDYLNGARNANTLLEKEFKKFTTKLHTHSPQSMRTDILFEMEKKYPEEFNRTLHNKFRSLDDIAVTGYLYHHYALLSGRALQSSDKTELVQQNHDFKKKLNNVVTLTKERNFDKLPLSVCINDGADSHLNEEWNVQVIKFLETLFPLPSSFEK
What is the function of this protein?
Part of a capsular biosynthesis operon and has been suggested to be the polymerase that links individual UDP-N-acetyl-D-mannosamine monomers.  In serotype A the capsule is composed of repeated units of (alpha 1-6)-linked N-acetyl-D-mannosamine-1-phosphate.  Non-polar disruption of this open reading frame prevented capsule synthesis.
What are the official names of this protein?
Capsular polysaccharide phosphotransferase SacB, Stealth protein SacB.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: NIKR_HALWD
Sequence: MSVVSVSMPEELLERIDQFADDHGYTGRSEVFREASRNLLEEFEDKRLENRELMGIVTVVFDYETTNVEEKMMHLRHEHEDIVASNFHSHVGGHHCMELFVLEGSLETISTFVGKIRATKNTLTIDYSVLPVDDFGPLAEMT
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: SRSF1_PIG
Sequence: MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT
What is the function of this protein?
Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing.  Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF.  Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA.  Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC.  Binds preferentially to the 5'-CGAGGCG-3' motif in vitro.  Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing.  May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway (By similarity).
What are the official names of this protein?
Serine/arginine-rich splicing factor 1, Splicing factor, arginine/serine-rich 1.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus speckle. Note=In nuclear speckles. Shuttles between the nucleus and the cytoplasm. Nuclear import is mediated via interaction with TNPO3.
Protein: COAD_BURCH
Sequence: MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLTIANEVLGHYPNVKVMSFTGLLKDFVRVNNARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVTAMGGPAA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRR10_ARATH
Sequence: MFSSSVSISILVVVAMQFSFIHNVLSLNQTNSYLQHICINSEGKYKAKNSYESRLKDHLDSMSNILDYGFIHGVGGADSSTYYIKAQCRGDASESKCRSCLFTAFSGILRRCPNNRGRIIWYDNCFLYISEIYTYEKIDFKHYLYLHNAKDVSGNKKLFNKNTKALLDKLKEKAIRKEQEPYTRDYMYAAGEESLGTTKLYGMMQCTQDLSVKNCSVCLDSIIAKLPRCCNGKQGGRVLNPSCTFRYELYPFVKP
What are the official names of this protein?
Putative cysteine-rich repeat secretory protein 10.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEPA_CHESB
Sequence: MPRMTNTPIKNIRNFAIVAHIDHGKSTLADRLIQMTGSLEEREMKEQVLDSMDIERERGITIKANTVRLEYDARDGEHYVLNLIDTPGHVDFAYEVSRSLAACESSLLVVDASQGVEAQTLANVYQAIDNNHEIVPVLNKVDLPAAEPERVKAQIEDVIGLDASDAIPISAKTGVGVDEVLEAIVMRLPPPHEGDASAPLKALLVDSWYDAYLGVIVLVRIIDGVLKKGQTVRMMGTGARYPVDRVGVMTPKMVMVESLGPGEIGFITASIKEVADTRVGDTITEDKRATAAALPGFKPAQPVVFCGLFPVDAADFEDLRAAVGKLRLNDASFSYEMETSAALGFGFRCGFLGLLHLEIIQERLTREFDLDLIATAPSVVYRMNLTDGKTVELHNPADMPDPVKIAEIEEPWIRATILTPDEHLGGILKLCQDRRGVQADLSYAGSRAMLVYDLPLNEVVFDFYDRLKSISRGYASFDYHLTDYREGDLVKMSILVNDEPVDALSMLVHRSQAERRGRAMCEKLKELIPQHMFKIPIQAAIGGRIIARETISALRKDVTAKCYGGDVTRKRKLLEKQKEGKKKMRQFGKVEIPQEAFIQALKMGD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.