PharMolix/UniProtQA huggingface dataset:
Protein: IHFA_CERS4
Sequence: MSDKTLTRMDLSEAVFREVGLSRNESAQLVESVLQHVSDALASGETVKISSFGTFTVRDKSARIGRNPKTGDEVPISPRRVLTFRPSHLMKERVAAGGKN
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: LGMN_RAT
Sequence: MTWRVAVLLSLVLGAGAVHIGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANNEENPTPGVVINRPNGTDVYKGVPKDYTGEDVTPENFLAVLRGDEEAVKGKGSGKVLKSGPRDHVFVYFTDHGATGILVFPNEDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDIDVYATTAANPNESSYACYYDEERSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPPVTHLDLTPSPDVPLTILKRKLLRTNNMKESQVLVGQIQHLLDARHIIEKSVQKIVSLLAGFGETAQKHLSERAMLTAHDCHQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEKPYPIDRIKMAMDKVCLSHY
What is the function of this protein?
Has a strict specificity for hydrolysis of asparaginyl bonds.  Can also cleave aspartyl bonds slowly, especially under acidic conditions.  Required for normal lysosomal protein degradation in renal proximal tubules.  Required for normal degradation of internalized EGFR.  Plays a role in the regulation of cell proliferation via its role in EGFR degradation.  May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system (By similarity).
What are the official names of this protein?
Legumain, Asparaginyl endopeptidase, Protease, cysteine 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
Protein: STIL4_ARATH
Sequence: MSRVASSRVLKDSNGDIGEHLRNHIHLTNCIHLKNHMHNNNKQSPVLTDRSLLMRDLVVLQRSRSLRDPSASPNLKEDHQDSREGRRRSGLRLSGSSPIVSFGTSKVTPSDEKFDRSSRKSYRVEEVNEVYSVPSVKSVSKDRINKKVNEAIVKTLSDQLNEVGGDSDDLVSCNVRPRGDGCRRRKFRGTRRAGRAVNVRDNAAGNESEMSIASNSVPRGEKYEGEEGGGGRDREQNMSCGIPFNWSRIHHRGKTFLDIAGRSLSCGISDSKGRKGEAGTPMFSDSSSSDREALPLLVDSADNEEWVHDYSGELGIFADNLLKNGKDSVIGKKSSRKNTRWHQSFTQKYAPRTFRDLLGQNLVVQALSNAIAKRRVGLLYVFHGPNGTGKTSCARVFARALNCHSTEQSKPCGVCSSCVSYDDGKNRYIREMGPVKSFDFENLLDKTNIRQQQKQQLVLIFDDCDTMSTDCWNTLSKIVDRAPRRVVFVLVCSSLDVLPHIIVSRCQKFFFPKLKDVDIIDSLQLIASKEEIDIDKDALKLVASRSDGSLRDAEMTLEQLSLLGTRISVPLVQEMVGLISDEKLVDLLDLALSADTVNTVKNLRIIMETGLEPLALMSQLATVITDILAGSYDFTKDQCKRKFFRRQPLSKEDMEKLKQALKTLSESEKQLRVSNDKLTWLTAALLQLAPDKQYLLPHSSSADASFNHTPLTDSDPSNHVVAGTRRDDSKQGFSCKNRPSVEDIWLAVIENVRVNGLREFLYKEGKIFSISIGSAPMVQLMFNSPIAKSTAENFEEHILKAFEAVLGSPVTLEMRTESKKDLGFSSLQGLSNGERFRESGRSEIVEVADSESPMTRVRRKHLEASQNQNQNQNQSIVRGKVSLAQVIKQAEGNSWSKHKAVEIANKLEQENLKLEPRSRSLICWKASRSTRRKLSRLKVRTRKLRLHSLLKLVSCGKCLSTRSPPR
What are the official names of this protein?
Protein STICHEL-like 4.
What is the protein family that this protein belongs to?
Belongs to the DnaX/STICHEL family.
Protein: GLGA_CHLCV
Sequence: MKIIQTAVEFAPFIKAGGLGDAVYGLSKALSESHDVEVLLPFFPLITPSFSSQVIDEKVFSYEFLGRQHAHSISYSYEGMILTIIKLDSQLDLFSTSTIYTEDDTLRFSAFSAAAAAYIGELDHVDIVHMHDWHMGLLSGLLKEPNRPHYPKRIFTIHNFSYRGYCSTQLLGTSGISDFGLSNYQLYRDPQMSVLLKGALYCSDYITTVSPTYAQEILNDYSDYEMHDAIMARRHVFCGILNGIDEQIWNPETDASLAVNYSKDLLDAPDVLFTKKEENKNALYEKLGLSYEYSPLMCIISRIVEQKGPEFMKAAILHAMENGYALVIVGTCYDPEIQRKFTNLQESLTTSPNIRIILDYNDPLARLVYGAADMICIPSHFEPCGLTQLIGMRYGTVPLVRSTGGLADTVVTGINGFTFSQTDNFNDFLHMLTLAITTYRQEPDIWFQLVEEGMLRSSGLTTMAIHYLGVYNSLL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: CMOB_PSEA7
Sequence: MIQHLALDALQRHLAGSPLYAWATSLPAQIAARIEEGHGDLARWWSAVQRLPQVQAPTVELAGRFALHSERDAALQPQVKEALQGLIPWRKGPFDFFGVQVDTEWRSDWKWSRVSPHVDLRGKRILDVGCGNGYYQWRMLGAGAESVIGIDPNWLFLCQFLAAKRYLADLPAWHLPLALEDLPEKLEGFDTLFSMGVLYHRRSPIDHLLALKDCLKRGGELVLETLVVEGDASTVLVPEDRYAQMRNVWFLPSVAALELWLRRAGFADARCVDVSLTSVEEQRATEWMRFQSLPEFLDPQDRSRTVEGLPAPMRATLVARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RL2_LEGPC
Sequence: MALLKSKPTSPGKRGEIRVVHHDIYKGKPHAALVEKLKKTGGRNNQGRITVRHIGGGQRQKYRIIDFKRNKDGILGRVERLEYDPNRTALIALISYKDGEKRYIIAPSNLEVGATIQSGADSPISVGNCLPLKNIPVGTTIHCVEMKPGKGAQMLRSAGCSGQLVAKEGVYATLRLRSGEMRKIHVLCRAVIGEVSNSEHNLRALGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGLPTKGYKTRSNKRTDTFIVRGRKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RPOB_METI4
Sequence: MNEKIQRINFGKIREGLSLPNLIEHQTKSYADFLQLSVAPQERKAEGLHGVFLEVFPIESYDGKVKLEYVNYEIGESKFSPIDCLRDGKTYAAPLYVTFRLKDEEGVKEEKVYMGELPMMTPQGSFIINGAERVIVNQLHRSPGICFESSFHSNGKTLYSFRIIPDRGSWLEVAFDTNDLLYVYLDRRKKRRKFLITTLLRALAAALSGPSSPLGSGGDEEIIRLFYTVEELNLSEGIDEDKVATKVLVSEVKDPHNPDVVLARAYEPVTRSVVRQLLDVGIQSISVVDVQYDDTLIKCLKKDPTKDPVEALKEIYRRLRPGDPPTESNAKLLLKRLLLDPKRYDLGRVGRYKLNQKLNIQVDPDIRILTWEDLVAATRYLIKLRKGEGITDDIDHLGSRRVRTVGELVANQCRMGLARTERLVKERMTLFDVNTEGMTPQKLINPKALSATIRDFFARSQLSQLMDQINPLSELTHKRRLSALGPGGLSRERAGFEVRDVHPSHYGRICPIETPEGPNIGLIATMASYSRFNDYGILETPYRKVLNGKVTNEIVYFTADQEENYVIAMANTAVSEDGTILDQRVAVRFRREFMEVEREKVEYMDVSPKQIVSVAAGLIPFLEHDDANRALMGSNMQRQAVPLIQPEAPIVGTGIEERVARDIQAVIVSEVDGTVSSVTGKEIIVTPTGSPVEQKKKKSKQGSEREGIVYKLNKFMRSNAGTCINQKPIVKKGQVVKKGDVLADGPSTQNGELALGRNLLVAFMPWNGYNFEDAIIVSERVVKEDLFTSIYIDEFEIVARDTKLGPEEITRDIPNVGDEALKNLGPDGIIRVGAEVKPGDILVGKITPKSETELAPEERLLRAIFGEKAADVKDSSLRVPSGTYGIVMDVRVSSGTARVRKEKINASEAKQKIKEIEERYDQKEEELREELTQALSNILLNEKIPLDVVNVETGEIIIPANRKITKVLLRKMAQAYDKIEIDPSPIRSKIFEIIGNFEAKFEQLRNDRELELDQIESGEDTEPGIIKQVKVFIANKRKLSVGDKMAGRHGNKGVVSKIVPVEDMPYLPDGTPVDIVLNPLGVPSRMNVGQVLETHLGIAAKKLGFNVATPVFDGVKEEKIREFLVKAGMDEDGKSILYDGRTGEMFNQRVVVGMIYMMKLNHMVADKIHARAVGPYSLVTQQPLGGKAQYGGQRFGEMEVWAMEAYGAAYILQELLTVKSDDVQGRTRIYESIVKGENYLETTTPESFNVLIKELQGLCLEVNIGQRSDVIGLSVKPTTPKALSGGEAA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PROB_ENTFA
Sequence: MRNKLQQAKRIVIKVGTSSLIYPNGNINLKAIDQLAFTLSDLSNQGKEIILVSSGAIGVGLNKLNLSVRPTTIPEQQAVAAVGQAELMNIYNQRFSTYSQQMAQVLLTRDVIEYPESRNNVTNTFEQLLKMNIIPIVNENDTVAIEELDHLTKFGDNDQLSAIVCQIVQADLLVMLSDIDGFFSDNPTVNKEATLFSEINEINEDLFQLAGGKGSRFGTGGMSSKLKAAERVLANQQAMILANGKQPKIIFEILEGKDIGTLFIKGGHESD
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP10_METKA
Sequence: MPKRLRRCKECGEYTLQRDKCPHCGGDLEVPHPHRFSPEDPYGKYRRKLKKRVWAEKFGPPSGEGD
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: RBL2_RHOPS
Sequence: MDQSNRYANLNLKESDLIAGGRHVLCAYIMKPKAGFGNFVETAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEAKELMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMHDFYVPPAYLRLFDGPSTTIKDLWRVLGRPVVDGGFIVGTIIKPKLGLRPQPFADACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVNDAMRRAQDATGQPKLFSFNITADDHYEMLARGEYILETFGENADHVAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHVGTMGYGKMEGEASDRDSAFMITQDSAEGPYFKQEWLGMNPTTPIISGGMNALRMPGFFANLGHSNLIMTAGGGAFGHIDGGAAGARSLRQAEQCWKQGADPVAFAKDHREFARAFESFPNDADKLYPNWRNMLKLAAA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type II subfamily.
Protein: RECA_CORA7
Sequence: MATKKKSSAANKGDDRQKALDAAMAMIEKDFGKGAVMRLGDDDRPPIQAISSGNTAIDIALGVGGFPRGRIVEIYGPESSGKTTVALHAIASAQKTGGIAAFIDAEHALDPEYARLLGVDTDNLLVSQPDTGEQALEIADMLVRSGAIDIIVIDSVAALTPKAEIEGEMGDSHVGLQARLMSQALRKMTGALYNSGTTAIFINQLREKIGVMFGSPETTTGGKALKFYASVRCDIRRIQTLKDGQDAIGNRTKLKVVKNKVSPPFKIAEFDIMYGEGISRESSIIDLGVEHGFIKKSGSWFTYEGDQLGQGKEKARNFLKDNPDLADEIEKKIFVKLGVGAAAAEAGEDVAMDVPGADDPLTDEAVDLVPNVDFDDD
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR11_PHAVU
Sequence: MAKYIPKTGSRKNVRIGSRNHTRKIPKGIIHVQASFNNTIVTITDVRGRVISWSSAGTCGFKGTRRGTPFAAQTAAGNAIRTVSDQGMQRAEIMIKGPGLGRDAALRAIRRSGILLNFIRDVTPMPHNGCRSPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HXA5_MORSA
Sequence: MSSYFVNSFCGRYPNGADFQLHNYGDHSTANDQYRDSTAMHSSRYGYGYNGMDLTVGRAGTGHFVGNERTQGYSPSHSAATTPSVEPVRYTQSANSTGTSSLSPPPDPLPCSSVASSSPVTETQSQHRAVKNSITTPCSTPCSSSNGGTLLLNRDCVSKASPLEEEKPAGSAPTTPQNVSDSTQPQIYPWMRKLHINHDLAGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMNMAAAGGGGYRP
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A5.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: F107B_HUMAN
Sequence: MAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQES
What are the official names of this protein?
Protein FAM107B.
What is the protein family that this protein belongs to?
Belongs to the FAM107 family.
Protein: HOT_RAT
Sequence: MAAAARARVTHLLRHLQSTACQCPTHSHTYSQVPGLSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKNVCLMTDKNLSQLPPVQIVMDSLSKNGISFQVYDNVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYACSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYSMRSPCPSNPIQRPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDLEARSSMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAEILGANIRTAKIQDAGPVLADALRKFLFDLNVDDGLAALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY
What is the function of this protein?
Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG).  L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).
What are the official names of this protein?
Hydroxyacid-oxoacid transhydrogenase, mitochondrial, HOT, Alcohol dehydrogenase iron-containing protein 1, ADHFe1.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YIDC_CHLPN
Sequence: MNKRTLLFVSLIGIAFVGCQIFFGYNEFRSCKNLAEKQRKISEQTLAAVESVGLSVASWDTDVNGEEHKNNYAVRVGDKLFLLHNGEAAQSVYSSGESWSFVDHKCGFDNIHLALYRQQGSSFNPTNTGKVFLPTNHEGLPVLVVEFRNNKEPLVFLGEYAQGRISNKDSTIFGTALVFWRSGSDYIPLGLYDSREEKLVSLDLPITRAVIFGNDQDSAKSSDTANHYVLFNDYMQIIVSEESGSIEGINLPFASTNNKSIVNEIGFDRDLASEKSPEALFPGLSSKLPDGQQAKNSIGGYYPLLRRGLLSDSKKLLPLEYHALNVVSGRELATPVALRYRVLSYTPHSIQLESLDRSVQKVYKLPENPEEKPYVFETAITLTKETEDVWVTSGVPEVEIMSNASAPTIKYRVIKKNKGSLDKVKLPKVKEPLAVRRGVYPQWILNSNGYFGIILTPLSEIASGYGSLYISGSTAPTRLSAISPKNQLYPVSKYPGYETLLPLPKDAGTHRFLVYAGPLAEPTLKVLDKTITQEKGENPEYLDSISFRGVFAFITAPFAALLFIIMKFFKLVTGSWGISIILLTVFLKLLLYPLNAWSIRSMRRMQILSPYIQQIQQKYKNEPKRAQMEIMGLYKTNKVNPITGCLPLLIQLPFLIAMFDLLKSSFLLRGASFIPGWIDNLTAPDVLFSWQTSIWFIGNEFHLLPILLGIVMFLQQKVTSLHKKGPVTDQQKQQQVMGNMMAILFTAMFYNFPSGLNIYWLSSMILGVVQQWITNKILDSKHLKNEVVLNNKKHR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEG10_XENTR
Sequence: MVHSLKWLGIFPLILFQWLGTTSSLNLEDPNVCSHWESYSVTVQESYSHPYDQVYYTSCTDILNWFKCTRHRISYRTAYRRGEKTMYRRKSQCCPGFYESREMCVPHCADKCVHGRCIAPNTCQCEPGWGGPNCSSACDVDHWGPHCSSRCQCKNGALCNPITGACHCSSGYKGWRCEERCDQGTYGNDCQQKCQCQNGASCDHVTGECRCPPGYTGAFCEDLCPPGKHGSQCEERCPCQNGGVCHHVTGECSCPAGWMGTVCGQPCPEGRYGRNCSQECQCHNGGTCDSATGQCYCSPGYNGERCQEECPVGLYGVKCAQTCQCLNGGKCYHISGACLCEPGYTGERCETPLCSEGTYGMKCDKKCPCHLQYTQSCHPMSGECACKPGRSGLYCNETCSLGFYGEFCQQICSCQNGADCDSVTGKCICAPGFTGVDCSTACPPGTYGVNCSSLCNCKNNAVCSPVDGSCTCKAGWHGVDCSINCPRGSWGLGCNLTCQCLNGGACNPLDGTCTCAPGWRGLKCELPCQDGTYGMNCIERCDCSHADGCHPATGYCRCLAGWAGMHCDSVCPGGHWGPNCSLSCDCKNGASCSPDDGICECAPGYRGTTCQRICSPGFYGHRCSQACPQCVHSNGPCHHVTGQCDCLAGFMGSLCNEVCPSGRYGKNCAGVCACTNNGTCNPIDGTCQCYPGWIGNDCSQACPPGHWGPNCIHTCNCHNGAYCSAYDGECKCSPGWTGLYCTQRCPLGYYGKECTLVCQCQNGADCDHITGQCTCRTGFMGKFCEQKCPSASYGYGCRQVCDCLNNSTCDHITGTCYCSPGWKGARCDQAVMIVVGNLNSLSRTSAAIPADSYQIGAIAGIIILVLVVLFLLALFIIYRQKQKGKDTAMPAVAYTPAVRVLSTDYTIADTLPHNNVVNANSQYFSNPSYHTLSQCTTGPQVNSMDRMMVSRSKSSQLFVNLKNLDPGKRSHTIDYTGTLPADWKQGGFLNENGLLKNSAYSISTCSLSSTENPYATIKDPPVLLPKNIECGYVEMKSPARRDSAYAEISNSSLANKNVYEVEPTVSVVQGAFCNNGKISQDLYDLPKNSHIPCHYDLLPVRESSSSNKDESTSE
What is the function of this protein?
Membrane receptor involved in phagocytosis.  May also regulate homotypic retinal neuron repulsion.  May play role in cell adhesion and motility.  May also be an essential factor in the regulation of myogenesis, controlling the balance between skeletal muscle satellite cells proliferation and differentiation (By similarity).
What are the official names of this protein?
Multiple epidermal growth factor-like domains protein 10, Multiple EGF-like domains protein 10.
What is the protein family that this protein belongs to?
Belongs to the MEGF family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ARID5_ARATH
Sequence: MMADTEMQEQDVPSGTKGVVEEPSELEKDLNSIERPKSPVPEDTTHTLDSDVHLSDAPIANQIEANEEVGGQNSVDGRNGDVDQSEKKITSDGGQEETTLGESNPLKGDPSSPHVPEESVKKWKTWLLSDAEAREVDEAGAPQDQEAFIKEVEAFNKENFLEFKAPKFYGQPLNCLKLWRAVIKLGGYDVVTTSKLWRQVGESFHPPKTCTTVSWTFRIFYEKALLEYEKHLRQNGELNLPGSASLPSSGIEKEASSHQASGSGRTRRDAAARAMQGWHSQRLLGSGEVTEPIVKEKGLNSTPKQKNLKNIGVQKQKTTTGMDLVFSHESEKQSTAEVIDVGPPADWVKINVRETKDCFEIFALVPGLLREEVRVQSDPAGRLVIAGQPEQLDNPWGITPFKKVVNFPARIDPLHTSAVVSLHGRLFVRVPFEQ
What are the official names of this protein?
AT-rich interactive domain-containing protein 5, ARID domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROE_RHOPS
Sequence: MTQPTSQAHIAACLIGWPAAHSRSPLIHHYWLRKLGIEGGYSIESVPPEGFAEFVLHLKTHGYSGANVTIPHKERALQLTVPDQRACAVGAANTLYYDGSVLRSTNTDVEGFISNLDASAPGWDRTPHAVVLGAGGSSRAVVFGLLERGIQRIALANRSIERARALADLFGERVVPIAWTDAPAALPGAGLLVNTTSLGMKGQPSLDLDLEPLPADATVADLVYVPLETELLSEARARGLRTADGLGMLLHQAVRGFELWFGARPEVTSELRALVEADLVAHA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MURB_RICB8
Sequence: MNLPIVKGEYRKDYNLKHLTWFKVGGNAEIFFKPVDSEDLASFLVQNKQKLPITTFGAGSNIIIRDGGIEGVTIKLGQNFSNIGFTDDGHLIVGSSCLNFSLAKFCQVNAISGFEFLVGIPGTIGGGVAMNAGAYGCEFKDILVRIEAIDFAGNFRTFTNEEIGFKYRGNNLPKDLIILKAVFKVNKGNSEDILARMNEINAARSSTQPIKERTGGSTFANPEGFKSWQLIDKAGLRGYRIGDASISELHCNFMINNGNATAKELEDLGNFVQQKVFEDSGIKLNWEIKRIGKVSSRAWLDHGIQRKIIK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLGC_STAAS
Sequence: MLKNKILATTLSVSLLAPLANPLLENAKAANDTEEIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN
What is the function of this protein?
Toxin that seems to act by forming pores in the membrane of the cell.  Has a hemolytic and a leucotoxic activity (By similarity).
What are the official names of this protein?
Gamma-hemolysin component C.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: MDTB_ECOSM
Sequence: MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HV102_HUMAN
Sequence: MDWTWRILFLVAAATGAHSQVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGWVTMTRDTSISTAYMELSRLRSDDTAVYYCAR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 1-2, Ig heavy chain V-I region ND, Ig heavy chain V-I region V35.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: NUSB_VIBA3
Sequence: MGASVKPAARRNARQFALQAIYSWQITKENIATVEEQFLSGGKYDEEEHHAAEPALAMPETDVAYFRDLLTGVALSHMELDSKLRPFVSRPMQDLDLMELALLRLAMYEMTRREDVPYKVVINEAIELAKVFAAEDSHKFVNGVLDKAAPHVRKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: FOSA_SERMA
Sequence: MLQSLNHLTLAVSDLQKSVTFWHELLGLTLHARWNTGAYLTCGDLWVCLSYDEARQYVPPQESDYTHYAFTVAEEDFEPLSQRLEQAGVTIWKQNKSEGASFYFLDPDGHKLELHVGSLAARLAACREKPYAGMVFTSDEA
What is the function of this protein?
Metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin.
What are the official names of this protein?
Glutathione transferase FosA, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_BACC1
Sequence: MFRIGQGFDVHEFAEGRPLIIGGVTIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.