PharMolix/UniProtQA huggingface dataset:
Protein: CRSP1_SHEEP
Sequence: MGFWKFPPFLVLSILVLYQAGMFHAAPFRSVFDGRFDPATLDEEESRLLLAAMVNDYEQMRTRESEKAQKTEGSRIQKRACNTATCMTHRLAGWLSRSGSMVRSNLLPTKMGFKIFSGPRRNFWF
What is the function of this protein?
Stimulates cAMP production via the calcitonin receptor (CT) but not via the CT-like (CL) receptor.
What are the official names of this protein?
Calcitonin receptor-stimulating peptide 1, CRSP-1.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YUAE_BACSU
Sequence: MSIFNEARLETWNELKGLSDEKLNQKPSAEEWSIREVLDHLKKIDMTAQKMLKERVKDAPIKEIEEKPLEVAQDRNNKRKAPSHLEPAHDFISGSQMKRELDVVREQLTAAIASLKEEDFERVLPHPVFQELTVRQWIDFIGHHEKRHLSQMKEIKEKIERA
What are the official names of this protein?
Uncharacterized protein YuaE.
Protein: SYK_BACC1
Sequence: MDNMNHEELNDQLLVRREKLHNLREQGIDPFGKRFERTNATNELLSLYGEFSKEELEEKEISVSIAGRIMTKRGKGKAGFAHIQDLHGQVQIYVRKDAVGDEEYELFKTADLGDLVGIEGKVFKTNVGELSVKATGFTLLTKSLRPLPDKYHGLKDVEQRYRQRYLDLITSMESRETFVTRSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFITHHNALDMELYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMKLTENMVAHIAKQVLGTTTIQYGDYEINLEPEWTRLHMVDAIKEHSGADFWNPMSVEEARELAKEHNVEIKDTMEVGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDEDPRFTDRFELFIVAREHANAFTELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPAMRHKQD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_BRUA4
Sequence: MTDRTCLSIVLAAGEGTRMKSNLPKVLHQVAGLPLVSHVVTAVQGTGKSDIALVVGRGADDVRAAVEKNAGPVSAFEQKERLGTAHAVLAAREAIERGYDDLLIVFGDTPLIEAQSLQKARERLAEGADVVVIGFRPDNPHGYGRLIEKGDKLVAIIEEKEATEEQKQIGFCNGGLMAVRGQHALALLDAVGNDNAKGEYYLTDIVAIAHSKGMNVTAIEVPVDNVIGINNRVELAEAEAIWQQRKRREMMLAGVTLIAPETVFFSHDTLIEADVIVEPNVFFGPRVHVATGALIHSFSHMEGAYVGPKAEIGPFARLRPGANLGEKTKVGNFCEVKNATVHKGAKINHLTYIGDATVGASSNIGAGTITCNYDGYNKYKTVIGENAFIGSNSSLVAPVEIGDNAYIASGSTITDNVPADALAFGRARQETKEGRAKILREKYAAIKAAKTATK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RABL_DICDI
Sequence: MKEEKTMLKIITLGDSNVGKTSLFYHYVNGEYRYNRPPSIGPDYFIKELKVENKHVFLMVWDTCGQERFQAFSPPYFRGANCYTLCFDIHNEESFINLGKWMDEIIKYCYGNIPFVLVGTKSDIPRTDKSISKARIEQWCKNIEDQGIIDKVHYFETSAKLSQNVTELYNVAAKLALEHYSIVKYISIIRPIGPPEEVKVGTCC
What are the official names of this protein?
Ras-related protein RabL.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RLMH_LISW6
Sequence: MNIQIITVGKLKEKYLVQGIAEYLKRLTAYAKVTIVEVPDEKAPEVLSDAEMKQVKDKEGVRILAKIPDDTHVIALAIDGKMKSSEEFAADLDKLATYGKSKVAFVIGGSLGLSESVLKRSDEQISFGRLTLPHQLMRLVLVEQVYRAFRIVRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MHX1_ORYSJ
Sequence: MANINMADTVPSCDTYLLFNGETLLPIGVRAFIYTAVLAYCFIGLSAITGRFFKSMESIMRHSREVVTVDPHTNATIVKHEKVWNYTIADVALLAFGTSFPQISLATIDAIRNLGQLTAGGLGPGTLVGSAAFDLFPIHAVCVVMPRAGSKKKISDLGVWLVELFWSFWAYIWLYIILEVWTPRVITLWEALLTVLQYGLLLLHAYAQDKRWPYVSIPLARGERPEDWVPAEDASVDYDDNYDGIGDILPGQNEDIVDIFSAHSYSNEGYHHVSEEDVEESSTGLTLKNKWEDTHWFSIWWQQFVDAATLESSVSRKMDSTCLRVIGISWNLIIAPWKMLFAFVPPYEIAHGWIAFICSLIFISGIAYGVTKITDQISCVTGVSPYVIAFTALAAGTSWPDLVASKIAAERQITADSAITNITCSNSVNIYVGIGVPWLVDTMYNYFVYQKPLYIDNAAGLSFSLLVFFATSFGCITVLVLRRVILGAELGGPRMWAWATSVYFMILWVVFVVLSSLKISGVI
What is the function of this protein?
Vacuolar transporter that exchanges protons with Mg(2+), Zn(2+) and Fe(2+) ions.  May control the partitioning of Mg(2+) and Zn(2+) between plant organs (By similarity).
What are the official names of this protein?
Magnesium/proton exchanger 1, Mg(2+)/H(+) exchanger 1, Zinc/proton exchanger 1, Zn(2+)/H(+) exchanger 1.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. MHX subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RS19_ECOBW
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PUR9_CERS4
Sequence: MTNLVPVGRALLSVSDKSGLLDLARALADLEVELISTGGTAAALRAAGLKVRDVAEVTGFPEMMDGRVKTLHPMVHGGLLALRDDDEHLVAMAAHGIEPIDLLVVNLYPFEAAVARGASYDDCIENIDIGGPAMIRAAAKNHRFVNVVTDTADYKALLDELRAHDGATRLSFRQKLALTAYARTAAYDTAVSTWMAGALKAEAPRRRSFAGTLAQTMRYGENPHQKAAFYTDGSARPGVATAKQWQGKELSYNNINDTDAAFELVAEFDPAEGPACVIVKHANPCGVARGATLAEAYARAFDCDRVSAFGGIIALNQPLDAATAEKITEIFTEVVIAPGADEEARAIFAAKKNLRLLTTEALPDPLAPGLAFKQVAGGFLVQDRDAGHVDALDLKVVTKRAPSDAELADLLFAWTVAKHVKSNAIVYVKDGATVGVGAGQMSRVDSTRIAARKSQDMAQALGLAQPLTQGSVVASDAFFPFADGLLAAAEAGATAIIQPGGSMRDDEVIAAADEAGLAMVFTGQRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: HYAL4_CERCE
Sequence: MYHIWIKFLAAWIFLKRFNGVHVMQAKAPMYRNEPFLVFWNAPTTQCRLRYKVDLDLKTFHIVSNANDSLSGSAVTIFYPNHLGVYPHIDDRGHFFHGIIPQNESLTKHLNKSKSDINRIIPLKAFHGLGVIDWENWRPQWDRNWGSKNVYRNRSIQFARDLHPELSEDKIRRLAKKEYEKAAKSFMRDTLLLAEEMRPDGYWGYYLYPDCQNYDYKTKGDQYTGKCPEIEMSRNDQLLWLWRDSTALFPNVYLEIILRSSDNALKFVHHRLKEAMRIASMAREDYALPVFAYARPFYAYTFEPLTQEDLVTTVGETAAMGAAGIVFWGSVQYASTVDSCQKVKKYMNGPLGRYIVNVTTAAKICSRVLCRKNGRCVRKHSDSNAFLHLFPESFRIMVYANATEKKVIVKGKLELENLIYLRENFMCQCYQGWKGLYCEEYSIKDIRKI
What is the function of this protein?
Snake venom endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments.  In venom, it is not toxic by itself, but increases the diffusion of other venom proteins by degrading the extracellular matrix.  In addition, it displays antiedematogenic activity (By similarity).
What are the official names of this protein?
Hyaluronidase-4, Hy-4, Hyaluronoglucosaminidase-4, Venom spreading factor.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACDH1_MYCSJ
Sequence: MPDKAGRKMQVAIVGSGNISTDLLYKLLRSEWLEPRWMIGIDPQSEGLARARTLGLETSHEGVDWLLARDELPDMVFEATSAYVHRDAAPRYAEAGIRAIDLTPAAVGPGVIPPANLREHLDAPNVNLVTCGGQATIPMVHAVSRVVGVPYAEIVASVSSASAGPGTRANIDEFTKTTSKGVETIGGARRGKAIIILNPADPPMIMRDTIFCAIPEDADQDAITASIKEVVAQVQTYVPGYRLLNEPQFDPPSVNSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAAKLAGASLSASSGGRS
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: LEUD_ECOUT
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CH60_ECO45
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM32_YEAS7
Sequence: MLITRLRVPTIKRPLLPITSHLVRHCIRTYVATNHGNVRPFITPYKSSLPVRCLIAQRHIRTFPSNDKFTTKASNIETILLRKNNEREFKQSLLADAKNFQERFKINLKWILIKNNRPFSLNEISIIASWLILSQILWLILSTTTFISFYLFVINSVFSQEYIHEKKIYERLLKWLLKDHKCSNQDLEITFSPEDKASMLVLSPDWESNSILIKRLNVRDEILDLDLKFHHINLNVSLKNWLLGRGLITNVSIYGIRGCLNLSNFINLVNSFQGDQKTENFLKTLNNVEITDSEILLKQSLSAQETPSLKFSIYNLSLPRLRLNHFISDILSAKTFSGSINNSLFNLFKRQQKLTAVIENNNKNRMASSKFDFTDNNQENYRTVTHQDDPNYVTTLRLNFININDLKFNGNGKFNWLKDGQVEILADIMLTNSTSHLSSESKYAVVDLKVTCRDLKTTFPQEPPVLSTGDSIVSLDELKPIITFINSYEGMANPILKDFSENERLTNSIIWNSPNVSINRQRKSYPLTTKVTSNSTKEIIKFHNQPNTNANEIVLRCKMVKNLSDLQLININQILDQITMELYVDLTKIVEDWEFKNKNDWMKQWGTTFASQLLLFGFGAMV
What is the function of this protein?
Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria.  Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures (By similarity).
What are the official names of this protein?
Mitochondrial distribution and morphology protein 32.
What is the protein family that this protein belongs to?
Belongs to the MDM31/MDM32 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FTSZ_PORGI
Sequence: MEDELLNFNYTDSGLPVIIKVIGVGGGGGNAVKNMYHGKVRDVSFLLCNTDVQALDRSEVPDRLVLGREVTNGLGAGSRPEVARRAAEASEADIRKILDDGHTRMVFVTAGMGGGTGTGAAPVIGRIARELNILTVGIVTIPFVFEGKRKILQALEGVEEMRKNVDALLVVNNERLRIIYKDLKLDNAFAKADETLTNAANGIAEMIMKEGTINLDFADVHTTLKDGGIAIISTGYGEGPDRMEQAINEALTSPLLNNNDIFKARRVLFNIYQGTEDPLGTDELSAINELTAKIETGFDTIWGYTTDPELGKKVKITILASGFDLDTTRESIRIGDNLGNVINDPISSREIETQNERDNDLINRYYRPDELEKVKVVDFKPIILNLDELDNDELIMALEEKPAYSRTGVLLSRIDNIRMRIAESAGRLKKDVVRSEESERPAFESERSSSPTTISFN
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: RPOC_ACET2
Sequence: MFELNNFDSIRIGLASPEKIREWSRGEVKKPETINYRTLKPERDGLFCERIFGPQKDWECHCGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEKILYFAAYVVIDPGQTPLSKKQILSEKEYRDSLEKFGPKFRAGMGAEAVRELLQEINLDELSAELREEIKQSTGQKRVRAIKRLEVVEAFRQSQNKPEWMILDVIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKIYQCGLPKEMALELFKPFVMKKLVNDGLAHNIKSAKRMVERVRNEVWDVLEEVIKEHPVLLNRAPTLHRLGIQAFEPVLVEGRALKLHPLVCTAYNADFDGDQMAVHVPLSAEAQAEARFLMLSANNLLKPQDGKPVAVPTQDMVLGSYYLTILKEGAKGEGRVFTSMDEAVMAYDNGEIELHSKIKVRMKRVVDGVEKSKIIETTLGRLIFNEAIPQDLGFVDRSDPDKIFDLEVDFLVGKNELKKIIDKSIKVHGTTKTAILLDKIKELGFKYSTKGAITISISDMVIPEVKAKYIKETEEKIEKITKQYKRGLISDEERYNSVIAAWTEASENITRALINNLDRFNPVYMMSQSGARGNINQIKQLAGMRGLMADTSGKTIEFPIKANFREGLTVMEFFISTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVRETDCGTRKGIEVTDIKDGNEVIEELSERIIGRYPVGNIVHPETGEIIVEAGRMITDQDAEKIVKAGIKKVRIRSVLTCHSEYGVCAKCYGANLATGEECNVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGEDITQGLPRVEELFEARKPKGLAIISEIKGTVKISETKKKREIVVTSEDGETRSYLIPYGSRIKVSDGDQVEAGDELTEGSVNPHDILKIKGVEAVQTYLVHEVQKVYRMQGVDINDKHIEVIVRQMLRKVKVEDPGDTSLLPGGLVDVFDFEEENAKAIAEGKKPAVAKRALLGITKAALATDSFLSAASFQETTRVLTEAAIKGKVDPLVGLKENVIIGKLIPAGTGMSRYKDITISTVTE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: KBX2_TITSE
Sequence: MVATNRCCVFALLFALLLVHSLTEAGKGKEILGKIKEKIIEAKDKMKAGWERLTSQSEYACPAIDKFCEDHCAAKKAVGKCDDFKCNCIKL
What is the function of this protein?
Shows cytolytic effects on erythrocytes.  In addition, induces non-selective pores formation when high concentrations (300 nM) are applied on oocytes.
What are the official names of this protein?
Tityustoxin-19, Ts19, Potassium channel toxin beta-Ktx 2.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RECU_STAAM
Sequence: MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEAYFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWKRYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLILDESEDRV
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSND_MOUSE
Sequence: MADEKTFRIGFIVLGLFLLSLGTFLMSHDRPQVYGTFYAMGSVMVIGGVIWSMCQCYPKITFVPADSDFQGILSPKALSLLETGLSEVKSPQPPYVRLWEEAAYDQSLPDFTHIQMKVMGYSEDPRPLLAPELKTGASSVREGEPRTAQAWMEAPVVVHRGSDENEGEKSHSQSSPSVGPQGSAPLASFHDDLDVGSSEGSSLQPSPNRDEPHRQVPWASRGPLDRFSDFALIDDTPTSEDTVLDGQAREAALPRKQQWSLRMKGETVQARAEEPEQEEEDLYYGLPDSPGNPLPDKELGFEPDIQG
What is the function of this protein?
Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels.  In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux.  In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
What are the official names of this protein?
Barttin.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Note=Staining in membranes of the renal tubule is basolateral. Also detected in basolateral membranes of intercalated cells of the collecting duct, which are known to express CLCNKB as well. Both acid-secreting alpha-intercalated cells and base- secreting beta-intercalated cells express this protein basolaterally, but intervening AQP2-expressing principal cells appear devoid of protein expression. In the inner ear, colocalizes with CLCNK in K(+)- secreting marginal cells of the stria vascularis. The basolateral staining contrasts with the apical localization of the KCNQ1 K(+) channel. Also found in K(+)-secreting vestibular dark cells, where it colocalized in basolateral membranes with CLCNK below apical membranes that expressed KCNQ1.
Protein: PSA5A_ARATH
Sequence: MFLTRTEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKEGVVLAVEKRITSPLLEPSSVEKIMEIDDHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGEEESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQFNKDLSLQEAETIAVSILKQVMEEKVTPNNVDIAKVAPAYHLYTPQEVEAVIARL
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-5-A, 20S proteasome alpha subunit E-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VCG3_NPVOP
Sequence: MDTVRLQCHICCSVGEIKNYFLQPVDAITILPIVELHTCRHQLCVMCVRKIAQRGRDKRVECPMCRRKNAHFNVYSVNRNSVDVLRCSVADVREHGRFGGLADAASLARGLFEPSLLEAEPAPDNSFGPNELQLVLKRLKAQIEAQTRTNYDLQLQATALERTIEEANDRLGKSRGDYSDACKLMDELRGDRLRAERAVKALADAHAQWADKNAKMRRENDRLTNENIGLIRDNNLFKQNTARKRKIAP
What are the official names of this protein?
Zinc finger protein CG30.
Protein: NIT2_NEUCR
Sequence: MAASTTTPTATTRPFFTMNPTTTEHDFRFPRRPGDSMAGTGLGGAAMSSSSANNNHNQHHPMSAFNHHHHHNAAGSARGRDSDGRPSSSNNNTSNGFVANINHQSSSNNNISKNIPPPTSDYHTQSASNGAAAYDLLRSSAFPPFQDGLAGMTQSPDEMQKQDPLATQVWKYFAKTKLALPNQERMENLTWRMMAKPLQTYRRQMETDRTHRFSESAPQKSTSGIARLRKSSEQTQSQGSDLMNLDDFINGENISTPAGLSLAPSPETSSKMADDRTAHHSTASAIPIKARKDQQSQHMIPQSVPAALHHPRMQTEFGYLPRHLRKTSIDETSKRNPNRKRPADFSPHVSAVTPSYVTNGLDADTDLHDYSLDHTSHDGLPPQTAPSSVPYALDTVGLDADTFITSAGPFQQNFSFSPSTSPMVSHDPFTAMFGPNNSSMHSGPINGNNFYSPPASAFQSTASTPHPMNEGGDNFYFGVDMRRARQQPYQPGNHGMGNAMAHQFPYAGNGNMMFPASSAGQDPTPSFAAPNSFSGHIDPTQVFHNEQAVRSPGMSVLQDSLFTFGAESDGDEEDGGAFADRNLSISHDFSSQGMEEPAFDSPSMGWDPSLPGNFSTQAARYPGGPPRKQVTIGATTTDYVDNTGEWDGSGLPRSQSQSFRQSDLRKGKMSRTASTPGLSARMNPFERLAQSASHSPPADVGRSSGLSSVPASRPSSPPPGAKQGSTTNLQGAAGNSTDTPTTCTNCFTQTTPLWRRNPDGQPLCNACGLFLKLHGVVRPLSLKTDVIKKRNRGSGASLPVGGTSTRSKKNASMSAAARKNSTLSITSNANNQPPAQVATPPAQQQVRASSVNESESPASGPASGGNTAGSTPTSYHGSTGSTSGAVGGKSVIPIASAPPKSAPGPGAGSMSRRDTISSKRQRRHSKSAGSDQPVSAGAVSSSGMDVDSPANSTGSNETMPTFNPGGAFSGLPPTTQSSLGFGNGYINTPRPMVGPGGMMGMPNGQAGQMMGASSSSGPGSGPSRTGAEWEWLTMSL
What is the function of this protein?
Major nitrogen regulatory protein.  During conditions of nitrogen limitation it turns on the expression of genes for enzymes which are required for the use of a variety of secondary nitrogen sources, including nitrates, purines, amino acids, and proteins.
What are the official names of this protein?
Nitrogen catabolic enzyme regulatory protein, Nitrogen regulatory protein 2, NIT2.
What are the subcellular locations of this protein?
Nucleus.
Protein: HNRPC_HUMAN
Sequence: MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSKSGKLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSANGEDDS
What is the function of this protein?
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621).  Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621).  Single HNRNPC tetramers bind 230-240 nucleotides.  Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621).  May play a role in the early steps of spliceosome assembly and pre-mRNA splicing.  N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2.
What is the protein family that this protein belongs to?
Belongs to the RRM HNRPC family. RALY subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Component of ribonucleosomes.
Protein: EF122_ARATH
Sequence: MLTPFCSSHHLQEKMNSCQSNPTKMDNSENVLFNDQNENFTLVAPHPSSSYLTRDQEHEIMVSALRQVISNSGADDASSSNLIITSVPPPDAGPCPLCGVAGCYGCTLQRPHREVKKEKKYKGVRKKPSGKWAAEIWDPRSKSRRWLGTFLTAEMAAQSYNDAAAEYRARRGKTNGEGIKRRWR
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF122.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_VIBCM
Sequence: MANNKSAKKRAIQAEKRRQHNASRRSMMRTYMKKTVAAIAAGDKEAATAAFAVVTPILDRMATKGLIHKNKAARHKSRFFAAINAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: H2B1L_HUMAN
Sequence: MPELAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 1-L, Histone H2B.c, H2B/c.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FOLD_CHLAA
Sequence: MSARILDGKALAQELRAEAAAQIAELRTQIDRPPTIAVVQVGDDPAATRYVRSIDRLCQSLGAACRAIALPAETAQADLEATVATLSADDRIDGILLQLPLPAGLTLDGVLSRLAPEKDLDGIHPINAGLLAQGRPTLTPNTPAGGIELMRRYGIDIRGRRAAVVGRSAIVGRPMALLLLQADATVTICHSRTPDLGAVLRECDIIAAAAGRPGLITADMVKPGATVIDFGTNVLADGSMVGDVDFAAVAEVAGAITPVPGGTGPVTNIMLMRNLITATRTRLGI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.