PharMolix/UniProtQA huggingface dataset:
Protein: SODM1_STAAC
Sequence: MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe] 1.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: Y2934_RHOPS
Sequence: MTILKWALIFLVISVVAGIFGFTGVSAASADLARILFYIFAAIFIVLLILGFTIFRA
What are the official names of this protein?
UPF0391 membrane protein RPD_2934.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BCHB_CERSK
Sequence: MKLTLWTYEGPPHVGAMRVATGMTGMHYVLHAPQGDTYADLLFTMIERRGKRPPVSYTTFQARDLGSDTAELFQSACRDAYERFQPQAIMVGSSCTAELIQDDTGGLADALSLPVPVVHLELPSYQRKENFGADESFLQICRKLARPMERTEKVSCNLLGPTALGFRHRDDILEVTRLLEGMGIAVNAVAPMGASPADIARLGAAHFNVLLYPETGESAARWAEKTLKQPYTKTVPIGVGATRDFVAEVAALAGVAPVADDSRLRQPWWSASVDSTYLTGKRVFLFGDATHVIAAARVARDEMGFEVVGMGCYNREFARPMRAAAKGYGLEALVTDDYLEVEEAIQALAPELILGTQMERHIAKRLGIPCAVISAPVHVQDFPARYSPQMGFEGANVLFDTWIHPLTMGLEEHLLTMFREDFEFHDEAGPSHHGGKAVPASAPRADEAAEALPATGAETAEGGSIPPEAVPPAAAAAAEAPAGEIVWLTDAERELKKIPFFVRGKARRNTEKFAAEKGLTRISIETLYEAKAHYAR
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: THIE_BACFN
Sequence: MLSLQFITHQTENYSYLESARMALEGGCKWIQLRMKEASPEEVEAVALQLKPLCKAKEAILILDDHVELAKKLEVDGVHLGKKDMPIGEARQMLGEAFIIGGTANTFEDVKLHHAAGADYLGIGPFRFTTTKKNLSPVLGLEGYTSILAQMNEAGIRIPVVAIGGIVAEDIPAIMETGVNGIALSGAILQAPDPVEETKRILNI
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: DDX27_BOVIN
Sequence: MLSELGFIRTIGEDEDVQVEPETDSEDEEEEGPIVLGRKQKALQKNRSADFNPDFVFTEKEGMYDGSWAMADVLSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKSEKEKEAKEGSEPEEEEDLERKDVEASEDEESETDYSSADENILTKADTLKIKERKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTKQLAQFCSITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLMRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQKSEAQINTAQRLLEKGKEAPNPEPERSWFQTKEERKKEKIAKALQEFDLALRGKKKRKKFMKEAKKKGEMTAEERSQFEILKAQMFAERLAKRNRRAKRARAMPEEEPVRAPAKKQKQVKKSVFDEELTNTSKKALKQYRAGPSFEERKKLGLPHQRRGGNFKSKSRYKRRK
What is the function of this protein?
Probable ATP-dependent RNA helicase.  Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX27, DEAD box protein 27.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome. Note=Associates with 60S and 90S pre- ribosomal particles.
Protein: PMTXB_BATMC
Sequence: RIKIGLFDQLSRL
What is the function of this protein?
Inhibits sodium channel (Nav) inactivation.  Shows two types of inhibitory activities on channels.  Inhibition of insect DmNav1/para and hNav1. 6/SCN8A shows a large increase in the steady-state current component without any increase in the slow component, whereas inhibition of hNav1. 1/SCN1A, hNav1. 2/SCN2A, hNav1. 3/SCN3A and hNav1. 7/SCN9A shows a large increase in the slow component with only a small steady-state component (PubMed:20059541).  Is 5-fold more potent than alpha-PMTX for inducing repetitive action potentials in lobster neuromuscular junctions.
What are the official names of this protein?
Beta-pompilidotoxin, Beta-PMTX.
What are the subcellular locations of this protein?
Secreted.
Protein: V_PI4HA
Sequence: MSFEISVEEIEELIETGNLNIDHALKELGATSQSSLNKPPSQSSRTEGNDGGTKISRNPAPVEAPAHTSTAQRSHNEENESGRQNLDSLSMISNKPQTGTLLMGSDTQLPSPSKTYQGLILDAKKRALNEPRRDQKITNEHGSMNDTRIFKRGEYRYQERGLGYTESEIKNTTPTPRHRREYSISWVNGRTTISEWCNPCCAPVKSTASVEKCTCGRCPKICELCIRDP
What is the function of this protein?
Blocks host interferon signaling.
What are the official names of this protein?
Non-structural protein V.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses V protein family.
Protein: FUMC_RHILO
Sequence: MTVAKTRTETDTFGPIEVAADRYWGAQAQRSLGNFKIGWEKQPASIVRALGVVKRAAAEVNMEMKRLDPVVGKAIVDAAQEVIDGKLNDHFPLVVWQTGSGTQSNMNANEVISNRAIEMLGGVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAEQVVHHLIPALHHLHKALDAKARAFNHIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLQELAQGGTAVGTGLNAPVGFAEKVADRIAAITGIAFVTAPNKFEALAAHDSMVFSHGAINAAAAALFKIANDIRFLGSGPRSGLGELSLPENEPGSSIMPGKVNPTQCEAMTQVCVQVFGNNAALTFAGSQGHFELNVYNPLMAYNFLQSVQLLSDASVSFTDNCVVGIEAREDNIKAALDRSLMLVTALAPTIGYDNAAKIAKTAHKNGTTLREEALATGLVSEVDYDRLVRPEDMTHPG
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_LEPBL
Sequence: MPTISQLIRHGRQKQKKRTKSPALKSSPQRRGVCTRVMTFTPKKPNSALRKVARVRLTTGIEVTAYIPGEGHNLQEHNVVLIRGGRVKDLPGVRYHIIRGTLDTLGVDKRRNGRSKYGAKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DNAJ_HELPY
Sequence: MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQAGASQGDFSDFFEDLGSFFEDAFGFGARGSKRQKSSIAPDYLQTLELSFKEAVFGCKKTIKVQYQSVCESCDGTGAKDKALETCKQCNGQGQVFMRQGFMSFAQTCGACQGKGKIVKTPCQACKGKTYILKDEEIDAIIPEGIDDQNRMVLKNKGNEYEKGKRGDLYLEAQVKEDEHFKREGCDLFIKAPVFFTTIALGHTIKVPSLKGDELELKIPRNARDKQTFAFRNEGVKHPESSYRGSLIVELQVIYPKSLNKEQQELLEKLHASFGYEGEPHKSVLETCISKIKDWFK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2150_STRE4
Sequence: MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVGYVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR
What are the official names of this protein?
UPF0297 protein SEQ_2150.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: METK_ACACA
Sequence: MASSKTLLFTSECVSESHPDKLCDQVSDAILDACLANDPYSKVACETASKTGMVMVFGEITTKSSFDYQKVIRETVKRIGFTDSSIGFDYKTCNILVAIEQQSPDIAQGVHVGRSDDDLGAGDQGHMFGHATNETPEFMPMTHVLATRLCQRMTEVRNNSILSWMRPDAKTQVTVEYRNENGTLIPLRRHTVVISVQHSEDVTNEEIRKRLMEEVIKPSIPAHLLDGETIFHLNPSGRFVIGGPQGEAGLTGGKIIIDTYGGWGAHGGGAFSGKDPSKVDRSAAYAARWIAKSLVARGLANRALVQVSYAIGVSHPLSVFVDSYGTAQGGRTDEDLLAISKSNFDLRPGKIINDLQLRRPIYEKTAYHGHFGRNDPDFLWEAPKKLNF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
Protein: TAM_RHOJR
Sequence: MWDPNKYLAFADHRGRPFYELLSRVDARSPRRVVDLGCGPGNLTVSLAERWPDAVLEASDSSPEMVEAARERGLDAGRQDVRDWTPKPDTDVVVSNAALQWVPEHRELLRRWPTQLPSGAWIAVQVPGNFDAPSHTIVRDLASRERWSRSLPDVPFRASTVVDDPADYAGLLADAGCAVDAWETTYVQRLTGENPVLEWITGTALRPVKDALSAPEWDLFREELAPLLDEAYPRRPDGSTFFPFRRIFVVAQVQ
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REV_HV1MV
Sequence: MAGRSEEDQQLLQAIQIIKILYQSNPCPTPAGSRNARKNRRRRWRRRQAQVDSLATRILATVVHGSQDNNLVDLPPLEQLNIRDPEADRLPGTGTVDPGTKDN
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: TIC62_PEA
Sequence: MPMEVFSLTSTAIPSTLTRRDTAADKPSPHLNLSKYSHFMRYPLTTTLTNNRIRSSSSSSSSIRAQASGSTKSSTAEGIPEKTDSKDDNLVFVAGATGKVGSRTVRELIKLGFKVRAGVRNAQKAGALVQSVKQLKLDGASGGGEAVEKLEIVECDLEKADQIGSALGNASTVICAIGASEKEIFDITGPCRIDYRATKNLVDAATVAKVNHFILVTSLGTNKFGLPAAILNLFWGVLIWKRKAEEALLASGIPYTIVRPGGMERPTDAYKETHNVTLSTEDTLFGGQVSNLQVAELMAIMAKNPDLSYCKIVEVIAETTAPLTPAEKLLTRIPSQRPYIPSPKKVQKADTATVSNTGPSANVVAEVPSIAPQKETASKPVAKTEQPLSPYTAYDDLKPPSSPSPTKPSEKKQINISDAVPTPISSDTPSSIQEIDGISQTTSSSKGKESLSPYAAYPDLKPPSSPSPSVPTTSLSKRDTVVVSSNGPAQLSVEDTPKNEEQHLHEPKSRPLSPYAMYEDLKPPASPSPSFRKS
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  Part of the redox regulon consisting of TIC32, TIC 55 and TIC62.  Has a NADPH-dependent dehydrogenase activity, but only after preincubation with lipids.
What are the official names of this protein?
Protein TIC 62, chloroplastic, Translocon at the inner envelope membrane of chloroplasts 62, PsTIC62.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Peripheral membrane protein. Plastid, chloroplast stroma. Note=Shuttles between the membranes and the stroma, depending on the redox state of the plastidic NADP(+)/NADPH pool.
Protein: TRPB_STAAE
Sequence: MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGGGSNAIGTFYPFIKDDVALYGVEAAGQGDDTDKHALAIGKGSPGVLHGTKMYLIQDEDGQVQLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMVERGLAND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SAHH_SACS2
Sequence: MSYKIKDLSLASEGKKQIEWAERHMPTLMEIRKRFKAEKPLKGINISAVLHVTKETAALVKTLKIGGANVALAGSNPLSTQDDVAAALVEEGISVFAWKGENETEYYSNIESIVKIHEPNIVMDDGADLHAYIHEKVSSKLDIYGGTEETTTGVIRLKAMEKDGVLKYPLVAVNNAYTKYLFDNRYGTGQSAIDGILRATNILIAGKIAVVAGYGWVGRGIANRLRGMGARVIVTEVDPIRALEAVMDGFDVMPIAEASKVGDIFVTATGNTKAIRVEHMLNMKDGAILSNAGHFNVEVDVKGLKETAVKVRNIRPYVDEYTLPNGKRVYLLADGRLVNLAAAEGHPSEVMDMSFANQALAVEYLVKNRGKLEKKVYNMPMELDYEVARIKLKSMGIQIDELTEEQKEYLEQWKSGT
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFT1_SCHPO
Sequence: MNDQNERRLETLSGQVSSLKNVTYDIYSRANDYTRIDRATESFSGLSNSVKKSTENFFRVVRSAGRRRIMTMVLAIVGSILIIYYASKWFF
What is the function of this protein?
Vesicle SNARE required for retrograde transport within the Golgi complex.
What are the official names of this protein?
Protein transport protein sft1.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein.
Protein: RLMH_LAWIP
Sequence: MSSKSLRLIVVGRLRIPFWRAAAEHYYKRISCWRAIYETIIKDGNSSLSVSQRKAMEGKNILAALEPIDIPICLDEKGKSISSQEFANFLRNYFENTTKRPCFIIGGAFGLDSSVCNIANDCLSLGNITFPHELARVIFLEQVYRAETLLRNIPYHH
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2198_PSYCK
Sequence: MMCYDNSEMLSRLIDVMANDKPLMLTSPKQRQGSRFEQRACEFLQERGLILVAQNWQQPKVGELDLVMLEKGQAWSTLVFVEVRQRQHSYFGDAAISVTAGKQRKIIKAARHFLQQNPQYHKYECRFDVIAYNTMNKKNKNEANITLDNQPNQRLEINQPEWLQGAFITSAW
What are the official names of this protein?
UPF0102 protein Pcryo_2198.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: Y309_RHOPT
Sequence: MSMAGAERPVSSAAGLPVRWALAVVLALLAIQATALFAMGRVPICTCGTVKLWHGVVQSSENSQHLTDWYTFSHIIHGFLFYAGTWLLLRRWSWTARLIVATLIEGGWELTENSSFIIERYRAGTISLDYYGDSIVNSVADTLAMISGFLLARWLPIAATVAIAVLFEVLVGLHIRDNLTLNVIMLIHPFDAIRQWQAGPPII
What are the official names of this protein?
UPF0314 protein Rpal_0309.
What is the protein family that this protein belongs to?
Belongs to the UPF0314 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS3A_XENTR
Sequence: MAVGKNKRLTKGGKKGAKKKIVDPFSKKDWYDVKAPAMFNIRNLGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVYVRKVKMLKKPKFELGKLMELHGEGGGAGKPAGDETGAKVERADGYEPPVQESV
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  May play a role during erythropoiesis (By similarity).
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_PONAB
Sequence: MGWKSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKCNPYMDSPQSIGFQATISAPHMHAYALELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDPTLLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSVKMKPLMGVIYVPLTDKEKQWSRWK
What is the function of this protein?
Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins (By similarity).  Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin C-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein (By similarity).
What are the official names of this protein?
Protein-L-isoaspartate(D-aspartate) O-methyltransferase, PIMT, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MURG_BURMS
Sequence: MTSTQRTLMVMAGGTGGHVFPGLAVAHRMQAQGWRVVWLGNPAGMEATLVPRHGIPMEYVRFGGLRGKGLATKFALPFNLLRACAQSLRALRRVKPDVVLGMGGYITFPAGLVTVLTGRPLVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPNAEWTGNPIRTELARTEPPQARYAARSGKLRLLVVGGSLGAAALNEVVPRALALLAPDERPQVVHQAGAKHIDTLKENYEAAGLSCGSDVALVPFIDDMASAYANADLVICRSGAMTVAEIAAVGVAALFVPFPHAVDDHQTTNAEFLAEQGAAVLVQQRDLSAELLADWLRGQSRDSLAAMAERSRSLAKPDATDEVARVCAAVAGANLEGKQ
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DOHH_DANRE
Sequence: MANDKDIAAVGSILVNTKQDLTTRFRALFTLRNLGGAEAVKWISEAFVDESALLKHELAYCLGQMQDESAIPTLEAVLKDTNQEPMVRHEAGEALGAIGNPKVLELLKKYAEDPVIEVAETCQLAVKRLEWLMNGGEQTKDGTDENPYCSVDPAPPAQRKSVPELRTQLLDETLPLFDRYRAMFALRNLGTEEAVLALGDGLQCSSALFRHEIGYVLGQIQHEASIPQLQAALEKMDENAMVRHECAEALGSIGKEPCVQILERYRKDQERVVKESCEVALDMLEYENSSQFQYADGLLRLQSAH
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A.  This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine.  Hypusination is unique to mature eIF-5A factor and is essential for its function.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
Protein: PIP_LACDA
Sequence: MMQITEKYLPFGNWQTYCRIVGEATDRAPLLLLHGGPGSSHNYFEVLDQVAEKSGRQVIMYDQLGCGNSSIPDDQAETAYTAQTWVKELENVREQLGLDQIHLLGQSWGGMLALIYLCDYQPEGVKSLILSSTLASAKLWSQELHRLIKYLPKGEQAAIKEAETTGNYDSLAYQAANAHFMDQHAIKLTPDLPEPVLRKKKGGSLAYLTGWGPNEYTPIGNLHGYEYTDRLKDLHLPALITSGTDDLCTPLVAKSMYDNLPNARWELFAGCGHMPFVQENAKYQELLSDWLISQD
What is the function of this protein?
Releases the N-terminal proline from various substrates.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cell envelope.