PharMolix/UniProtQA huggingface dataset:
Protein: NANE_STACT
Sequence: MLPQGLIVSCQALPDEPLHSSFIMSKLALAAYEGGAVGIRANTKEDIEAIKTEVPLPVIGIVKRDYEGSDVFITATSKEVDELIESGCEVIALDATKQKRPKETLEELVTYIRKHAPNVEIMADISTVEEAVNADKLGFDYVGTTLRGYTSYTKGHILFEDDFAFLKEVLDKVNAKVIAEGNVITPEMYQTVSNLGVYCTVVGGAITRPKQITERFVQAAKDQS
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: RECR_TROWT
Sequence: MYVRIVQDLIRELGKLPGIGPKSAQRITFFILQNPSFDIDRLSETLQSVRKQVQFCKVCGNFSEEDECVICSDPRRDRGVICVVEEPKDVVAIEKTREFSGLYHVLGGAISPIDGVGPDDLNIRQLLQRLADGTITEVVLATDPNMEGEATASYIARVISAMRIRVSKLASGLPVGSDLEYADEITLGRALEGRQYIN
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ISPG_LARHH
Sequence: MSSTGPGRRVCRQARIGHVLMGGTAPVVVQSMTNTDTADAAATALQVFDLWQAGSEVVRITVNSPEAAARVAEIRLRLDDMGCTAPLVGDFHFNGDRLLRDYPDCARALAKYRINPGNVGKGAKGDDKFAFMIRQAIEYDKAVRIGVNWGSLDQTLANRLMDENARRPHPLPAEAIMREALIISALDNAEKAVGLGLSPDQVILSCKVSHVQDLIAVYRELARRCDYALHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRVSLTPEPGESRTKEVVVAQEILQTMGIRSFTPLVTACPGCGRTTSTFFQELAQRIQGYLREQMPLWRAEYPGVEMLNVAVMGCVVNGPGESKLADVGISLPGTGEVPVAPVYVDGEKTVTLKGERIAEEFQAIVDAYVRKNYGEGGAKRRRVIAVRPA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SHBG_PHOSU
Sequence: MENRDSVASLLLLLLLLPPPHTHQGQVLRHVVPTQNSQDSPARYLSNGPGQEPVAVMTIDLTQMSKPYSSFEFRTLDPEGVIFYGDTNTKDDWFMLGLRDGQLEIQMHNPWAQLTVGFGPRLNDGRWHQVELKMSGDSLQLWVDGKELLCLRQISGTLANNSWPSMRIALGGLLLPTSSLRFPLVPALDGCLRRDTWLGHQVHLSPSAPNLGNCDVDLQPGLFFPQGTHAEFSLQDIPQPRTDPWSFSLELGLKLVDGSGCLLALGTRTNSSWLSLHLQDQKVVLSSGVEPKLVLALDMGLPLQLKLDILKVVLSQGPKTEVLGASASRLAALRTLWSHPQGLLSLGALAGDNSSASFCLSDLWVQGQRLDIDQALNRSQNIWTHSCPHSPNNVSHISH
What is the function of this protein?
Functions as an androgen transport protein, but may also be involved in receptor mediated processes.  Each dimer binds one molecule of steroid.  Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol.  Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration (By similarity).
What are the official names of this protein?
Sex hormone-binding globulin, SHBG, Sex steroid-binding protein, SBP, Testis-specific androgen-binding protein, ABP.
What are the subcellular locations of this protein?
Secreted. Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Protein: TGT_SCHPO
Sequence: MASSFPALQFKVVARCSTTRARVTDIQLPHGLVESPVFMPVGTQASLKGVLPEQLDALGCKIMLNNTYHLGLKPGQEVLDTVGGAHRFQSWNKNILTDSGGFQMVSLLKLATITEDGVTFLSPRDGTPMLLTPEHSISLQNSIGSDIMMQLDDVVHTLTESKRMEEAMYRSIRWLDRCIQAHKRPETQNLFCIIQGGLDKRLREICCREMVKRNTPGIAVGGLSGGEEKHAFCETVYTCTSILPDNKPRYLMGVGYAEDLVVCVALGMDMFDCVYPTRTARFGNALTRKGVINLRNQKFRNDIGPLEEGCSCPCCKTELEGGWGITRAYFNSLVSKETVGANLMTIHNVHFQLQLMRDMRESIIKDEFPSFVKNFFHEWNHGDKSNYPSWAVDALRMVNIDLLA
What is the function of this protein?
Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:24911101).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
What are the official names of this protein?
Queuine tRNA-ribosyltransferase catalytic subunit, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRMN6_ECO55
Sequence: MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVIIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_FUSNN
Sequence: MKIAIYGGSFNPMHIGHEKIVDYVLKNLDMDKIIIIPVGIPSHRENNLEQSDTRLKICKEIFKNNKKVEVSDIEIKAEGKSYTYDTLLKLIEIYGKDNEFFEIIGEDSLKNLKTWRNYKELLNLCKFIVFRRKDDKNIEIDNEFLNNKNIIILENEYYNISSTEIRNKVKNKEDISGLVNKKVKKLIEKEYID
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ARCA_STAAB
Sequence: MTDGPIKVNSEIGALKTVLLKRPGKELENLVPDYLDGLLFDDIPYLEVAQKEHDHFAQVLREEGVEVLYLEKLAAESIENPQVRSEFIDDVLAESKKTILGHEEEIKALFATLSNQELVDKIMSGVRKEEINPKCTHLVEYMDDKYPFYLDPMPNLYFTRDPQASIGHGITINRMFWRARRRESIFIQYIVKHHPRFKDANIPIWLDRDCPFNIEGGDELVLSKDVLAIGVSERTSAQAIEKLARRIFENPQATFKKVVAIEIPTSRTFMHLDTVFTMIDYDKFTMHSAILKAEGNMNIFIIEYDDVNKDIAIKQSSHLKDTLEDVLGIDDIQFIPTGNGDVIDGAREQWNDGSNTLCIRPGVVVTYDRNYVSNDLLRQKGIKVIEISGSELVRGRGGPRCMSQPLFREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCA_ECOSM
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: DCUP_DEIRA
Sequence: MRDSAFLKTARGEQAPYTPVWFMRQAGRYMPEYRALRAGKTMLECIRTPDLAAEITLQPIKAMPLDAAILFNDILTPLPTMGLSLDFVGGVGPVIHNPINTPKDVDVLGVPATAETMPYTAESIRLLMPELNSRGIPLIGFVGAPFTLASYAIEGKGSRNYEKTKRFMYAEPAAWARLMGKFESVLADYLTEQVKAGASAVQIFDSWVGALSVYDYQTFVKPATAGLIERVKKLGVPVIYFGTGATHLMPDMASLGSDVMGADWRTPLDKAWDLIQPGQSIQGNLDPLLLQAPWRELKHQTDRILHEANGRPGHIFNVGHGLLPETPQDMVHRLTDYVHEQTQR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGLB_ASPFN
Sequence: MRLRTSLGVASACASVASAALKVTEDNSTITLANDRLTSTFAKDKGRVSELFLDGQDLLGPISGNTGVGPYLDCYCIPSGFYTAGSTDPRLEVVQGTDSTGTKYAGVILNDTYTPTGQQFQQYWFLRDGETGLHTFSRLAYYNETTPFLRNLQEFRTLFRPNTELWTHLTSSEAQTAPLPSKEAIANEVVVQDATWRFNNTPNDAYYTQFSEYFTKYTFSNLWRDNSVHGLYADGTNSNGTTYGAWLVMNTKDTYYGGPLHSDLTVDGIVYNYLVSNHHGEGTPNITNGFDRTFGPQYYLFNGGKGSKSSLEDLRSEAETLADPGWNADFYDSIAKHVIGYAPSSKRGSVQGQVKLPKGSTRPIAILTVDGQYFQDNSVEASSHQYWAEMGQDGTFQLDHVKEGKYRLTVFADGIFGDFVHDGVEVQAGKVTKVQETWEQESAGVEVWRLGTPDKSSGEFLHGDAPDPTHPLHPPQHFIYWGAYDWQQDFPNGVNYTIGSSDPAVDFNTVHWSVYGPTPANPDVEYDTTHDWTINFSLDKKQLQQRKTATLTIQLAGAKTAAGNTDVYNATEPYANLALESYINEQKEPLTLLVGFNQSSSCIVRSAVSCYQVRSRMEFPADWLNVGNNVLTLHLPRNATDYETAVLPGTVYVQYDALRLELA
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).
What are the official names of this protein?
Probable rhamnogalacturonate lyase B.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PBAN_APIME
Sequence: MIGFAVFSSFNRFTTIFVCVLLCVVYLLSYASGEYDGRDSSSGSNNDRAPSNEFGSCTDGKCIKRTSQDITSGMWFGPRLGRRRRADRKPEINSDIEAFANAFEEPHWAIVTIPETEKRQITQFTPRLGRESGEDYFSYGFPKDQEELYTEEQIYLPLFASRLGRRVPWTPSPRLGRQLHNIVDKPRQNFNDPRF
What is the function of this protein?
A hormone that controls sex pheromone production in females and pheromone responsiveness in male.  Also mediates visceral muscle contractile activity (myotropic activity) (By similarity).
What are the official names of this protein?
PBAN-type neuropeptides, Pheromone/pyrokinin biosynthesis-activating neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NCBP2_HUMAN
Sequence: MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export.  The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore.  The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus.  The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E.  The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs.  The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC) via its interaction with UPF1, promoting the interaction between UPF1 and UPF2.  The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD).  During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with SRRT/ARS2, thereby being required for miRNA-mediated RNA interference.  The CBC complex also acts as a negative regulator of PARN, thereby acting as an inhibitor of mRNA deadenylation.  In the CBC complex, NCBP2/CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires NCBP1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.  The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (PubMed:26382858).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, Cell proliferation-inducing gene 55 protein, NCBP 20 kDa subunit, CBP20, NCBP-interacting protein 1, NIP1.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RPOC1_SYNY3
Sequence: MKAQSEPRFDYVKIAIASPERIRQWGERTLPNGTVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECWCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGIPSYLSILLDMALRDVEQIVYFNAYVVLNPGNASNLQYKQLLTEDQWVEIEDQIYAEDSELEGIEVGIGAEAVQRLLAELQLEEVAEKLREEILASKGQKRAKLIKRLRVIDNFIATHSQAEWMTLDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKIYQCGLPREMAIELFQPFVIHRLIKLGIVNNIKAAKKLILKGDPQIWSVLEEVITGHPVMLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLSLEAQCEARLLMLACHNVLSPATGKPIVAPSQDMVLGCYYLTAENPNAQKGAGRYFAGIEDALRAYDHGQVDLHSQIWIRHLDEDVVTEKPDTEVIKTEDLGDGTVMKYYRERKIREGVDGEIITQYIQTTPGRIIYNKTIAEALVF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: STX1A_PONAB
Sequence: MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVIPGIVIASTVGGIFA
What is the function of this protein?
Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis.  Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane.  STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles.  The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion (By similarity).  Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm.  Also plays an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1 (GLP-1) (By similarity).
What are the official names of this protein?
Syntaxin-1A.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell membrane. Synapse, synaptosome. Note=Colocalizes with KCNB1 at the cell membrane.
Protein: EME1_SCHPO
Sequence: MTLQSTDSAIVIDSEADVDISSSQASPSKDNIALSEHNVITVLDTPQRSTQCDSLLKSFSTPLVSGSEDVLPSPRDALNITNKKSVTDNLLLSLTSSNQSTNTNLNPSSRVEIINLNSSPPNSLSSQPKHQEFHLFHTPTIPRTTQLSSKTSSPIVIPDDNEQVASPLSKKAASLTSSPLKDFQSSPPLSTVLQKSHSLHDILLDTNDDDHFPFTQSPLTKTKSFNDALTSSSSILKPCMPSIASPTSNRLSHAPSTPNLFPNQDSSNTIDLINNRSKTSVENQERTFNLTSDVHLDSPTSPSKHSSIEPNTSQEDSFQELPSLNKLSIQSRAFKKMRLPKISRTTDTPPASTSNSNKKNLDKLKKMRKLCSRSLEPYELDSNTQRKRKRYEDSLKKSKTLDKVDSLNRKMAKELDRKNSKELQKINKVKRTKEECLSEIILLSPDDWASSWYSTVRSQLDSYNCQFVVNSNQPKDSIMWKRKVNNVFNSSTNRFELSIEHEQIEPFALLRLKCRDFIKYIEEDQADTFFHEMSEKFKGCKLILLLEGIPNYFKSLKAELNRQYAAAVNSGTRPLLFGSLSKYQNFTKEKLESEIVRFSFEHSILINTSNDEKETAQWIVSFTGDIALSRYKHFSKFSARASTTEIGHVKSADRIENSLNFMLRQILRVTPNIANAICDQFDSIPSLIHHLKTHGEESLTNVVIQSSISERNLGPVLSRRIYNTFLCKEASSDAP
What is the function of this protein?
Interacts with mus81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions.  May be required in mitosis for the processing of stalled or collapsed replication fork intermediates.  May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
What are the official names of this protein?
Crossover junction endonuclease eme1, Essential meiotic endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the EME1/MMS4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS16_HELPG
Sequence: MTVIRLTRIGRKKKPFYRVVVTDSRKRRDGGWIESIGYYNPLEPKDIKIDKERLNYWKGVGAKMSERVEKLSQKA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PP158_ARATH
Sequence: MEQSLVKALLKNTNNPRLAWRIFKRIFSSPSEESHGISLDATPTIARILVRAKMHEEIQELHNLILSSSIQKTKLSSLLSVVSIFAKSNHIDKAFPQFQLVRSRFPENKPSVYLYNLLLESCIKERRVEFVSWLYKDMVLCGIAPQTYTFNLLIRALCDSSCVDAARELFDEMPEKGCKPNEFTFGILVRGYCKAGLTDKGLELLNAMESFGVLPNKVIYNTIVSSFCREGRNDDSEKMVEKMREEGLVPDIVTFNSRISALCKEGKVLDASRIFSDMELDEYLGLPRPNSITYNLMLKGFCKVGLLEDAKTLFESIRENDDLASLQSYNIWLQGLVRHGKFIEAETVLKQMTDKGIGPSIYSYNILMDGLCKLGMLSDAKTIVGLMKRNGVCPDAVTYGCLLHGYCSVGKVDAAKSLLQEMMRNNCLPNAYTCNILLHSLWKMGRISEAEELLRKMNEKGYGLDTVTCNIIVDGLCGSGELDKAIEIVKGMRVHGSAALGNLGNSYIGLVDDSLIENNCLPDLITYSTLLNGLCKAGRFAEAKNLFAEMMGEKLQPDSVAYNIFIHHFCKQGKISSAFRVLKDMEKKGCHKSLETYNSLILGLGIKNQIFEIHGLMDEMKEKGISPNICTYNTAIQYLCEGEKVEDATNLLDEMMQKNIAPNVFSFKYLIEAFCKVPDFDMAQEVFETAVSICGQKEGLYSLMFNELLAAGQLLKATELLEAVLDRGFELGTFLYKDLVESLCKKDELEVASGILHKMIDRGYGFDPAALMPVIDGLGKMGNKKEANSFADKMMEMASVGEVANKVDPNARDIHQKKHNKNGGNNWQNILHRDDGSGIALRSLSRVKKGWGQGDISSFQPPRVDYLDYWEDDG
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g17140.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: CYB_ACIPE
Sequence: MANIRKTHPLLKIINGAFIDLPTPSNISVWWNFGSLLGLCLVTQILTGLFLAMHYTADISTAFSSVAHICRDVNYGWLIRNIHANGASFFFICLYLHVARGMYYGSYLQKETWNIGVILLLLTMMTAFVGYVLPWGQMSFWGATVITNLLSAFPYIGDTLVQWIWGGFSVDNATLTRFFAFHFLLPFVIAGASMIHLLFLHQTGSNNPTGLNSDADKVTFHPYFSYKDLLGFILMLVGLTSVALFSPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMLVPMLHTSKQRGNTFRPLSQILFWALVADMLVLTWIGGQPVEHPFVLIGQAASTVYFALFLIALPLTGLLENKALNWN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL30_KLULA
Sequence: MAPAKNQENINQKLALVVKSGKYSLGYKSTVKSLRQGKAKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVTILDAGDSDILTALA
What are the official names of this protein?
60S ribosomal protein L30, L32.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: TGT_ECOLU
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TTGR_PSEPT
Sequence: MVRRTKEEAQETRAQIIEAAERAFYKRGVARTTLADIAELAGVTRGAIYWHFNNKAELVQALLDSLHETHDHLARASESEDEVDPLGCMRKLLLQVFNELVLDARTRRINEILHHKCEFTDDMCEIRQQRQSAVLDCHKGITLALANAVRRGQLPGELDAERAAVAMFAYVDGLIRRWLLLPDSVDLLGDVEKWVDTGLDMLRLSPALRK
What is the function of this protein?
Represses expression from the ttgABC operon promoter and its own expression.  Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed.  This suggests that TtgR binds these antibiotics.
What are the official names of this protein?
HTH-type transcriptional regulator TtgR, Toluene efflux pump ttgABC operon repressor.
Protein: SAND_THEX5
Sequence: MNTETTSVRKFRSANIHIYGKCNYRCEHCFDRCLTKNYMRPSDWVDTLTFLKEYGVEKINLAGGEPTLYPFLDQMCYLVKGMGFKLSIVSNGSLITEDWMARMEGVVDWIGLSIDSIDEADEIQIGRGRGGHLENIVQVADMAHRHGIKVKLNITVVRRSWMKDFRPFIEKVRPERVKCFRALTLKNANDDVPDTWSITDKQFEDFRRRHEDIGCIVFEDNEDMVSSYVMFDPMGRWMVDSGYEKRFISFEVLRREGLDREVDVEKYFGRNAVYEW
What is the function of this protein?
Expression of pVip50 in E. coli (strain MG1655) confers resistance to phage P1; has no effect against T7.  Catalyzes the conversion of cytosine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP), probably via a SAM-dependent radical mechanism (PubMed:32937646).  The modified nucleotide represses transcription from T7 RNA polymerase-directed genes (possibly by acting as chain terminators), strongly suggesting these nucleotides block viral polymerase transcription (By similarity).  How this protein allows bacteria to resist viruses that do not encode their own RNA polymerase (such as lambda, P1) is unknown (Probable).
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase, SAND, Prokaryotic viperin protein pVip50, pVip50.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Viperin family.
Protein: PUR7_STAAE
Sequence: MTLLYEGKAKRIFSTNQENELRVEYKDEVTAGNGAKKDTMAGKGRLNNQITSIIFKYLQENGIESHFIKQLSETEQLVKPVKIIPLEVVVRNIASGSITKRLGFENGEVFREPLVEFFYKNDALNDPLITDDHVKLLNIASDEDIEILKSKALKINNVLKQLMDAMNLKLVDFKIEFGKTETGQILLADEISPDTCRIWDKATNANFDKDVYRNNTGSLIETYQIFLNKLEDLK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.