PharMolix/UniProtQA huggingface dataset:
Protein: TGB1_PMTVS
Sequence: MESGFNGSRPHRVKKDLPDRVNPVNTQGSSGTTGNAFRKNNNNKTQNWKPRSGPGNRNEGDQTKNNKSDLQQPSEVHPENQVRPESSTGESVKQQSEPHRVLEDKKQSGKTAGSSVRIPEEGGGGLGSANYLGKRQLDFVAKLCVESGFKSTGKPLKRYPAEFFKSSGLLEKFVKYLSSRLDKGCNLSQRESEVVLKNLRSKRAEQSFLAGAVTGVPGSGKTTLLRKVQCEGGFNSIVILGNPRSKTEFSNLPSCYTAKEILLLGIAIKCEVLLIDEYTLLTSGEILLLQKITNSRIVILFGDRAQGSSNTLCSPEWLQVPVIFQSLTSRRFGKATANLCRRQGFDFEGGEHEDKVVESPYEGSSPATDINIVFSESTREDLLECGIESTLVSDVQGKEYNTVTLFIPDEDREYLTNAHLRSVAFSRHKFALEIRCNPELFMQLINGELASKQQPQTDRYGPE
What is the function of this protein?
Participates in the transport of viral genome to neighboring plant cells directly through plasmodesmata, without any budding (PubMed:20923354, PubMed:12093178, PubMed:12655103, PubMed:21660184).  Multifunctional movement protein with RNA-binding, ATPase and helicase activities (By similarity).  Engages in homologous interactions leading to the formation of a ribonucleoprotein complex containing plus-sense viral RNAs (vRNPs) (By similarity).  ATPase activity is probably required for vRNPs movement complex assembly (By similarity).  Intracellular delivery of TGBp1-containing vRNPs to plasmodesmata is facilitated by TGBp2 and TGBp3 (PubMed:12093178).
What are the official names of this protein?
Movement protein TGB1, P51, Triple gene block 1 protein, TGBp1.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae/benyvirus TGB1 movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Host nucleus. Host cytoplasm. Host nucleus, host nucleolus. Host cytoplasm, host cytoskeleton. Note=TGB1 nuclear-cytoplasmic trafficking is required for cell-to-cell movement and systemic infection (By similarity). Associates with host microtubules (PubMed:20923354).
Protein: YGLB_BUTFI
Sequence: ILQEENKGLIIIMEDTKEDMDRFLDKNPSLKQSFNVRVDIQALDDDSLVAYARQYAYEKEYAIDNLGILALHTRISERQTLDHEVTVAEVKDIVDDAIYYAEKRSVAHFVDVLVNKRYDENDMVILREKDFMR
What are the official names of this protein?
Uncharacterized protein in glgB 5'region.
Protein: FABZ_BRASB
Sequence: MEESPIRFADVDINEILKTLPHRYPFLLIDRVKNIRADYSGIGVKNVSIGEPCFQGHFPERPVYPGVLMIEGMAQTAGVIGIKSVEGTEKPRAVYFLTIDKCKFRKPVLPGQTIEYHMRSIGRRKTMWWFHGDAKVDGTIVAEADVGAMLTD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE4A_CAVPO
Sequence: PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKDREPQEAPRQRPCQQLPPPVPHLQPMSQITGVKRLSHNSGLNNASIPRFGVKTDQEELLAQEL
What is the function of this protein?
Hydrolyzes the second messenger 3',5'-cyclic AMP (cAMP), which is a key regulator of many important physiological processes.
What are the official names of this protein?
cAMP-specific 3',5'-cyclic phosphodiesterase 4A.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: KCY_BACCN
Sequence: MDKRISIAIDGPAAAGKSTVAKVVAKQLSYVYIDTGAMYRTLTYAALEQNIDIENEEKLMEVLQSIRIEFQQGKDTQQVFLNGQDVSEVIRTPDVTNRVSIVAKHRLVREEMVRRQQELAAQGGVVMDGRDIGTHVLPNAEVKIFMLASVEERAERRHLENMRKGFSSNLEQLKKEIAQRDKLDSEREVSPLKKAEDAFELDTTSLSIEEVVRNIMAIVSEALQK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_CLOPS
Sequence: MKVHVRKNDTVVVISGKDKGKTGEVLRVIPKTGKVVVKGVNLVKKHQKPNRQNMQGGIIEMEAAINSSKVMLFCEKCKKATRISHKLLENGAKVRVCKKCGETF
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: P24D3_ARATH
Sequence: MKMTAKMRREFPTAFLLLFLVPVMIPVGEAVWLDVPPTGTKCVSEEIQSNVVVLADYLIISEDHEVMPTISVKVTSPYGNNLHNMENVTHGQFAFTTQESGNYLACFWADEKSHGNKNVSINIDWRTGIAAKDWASIAKKEKIEGVELEIRKLEGAVEAIHENILYLRNREADMRTMSEKTNSRVAWYSIMSLGVCIAVSGFQVLYLKQYFEKKKLI
What is the function of this protein?
Involved in vesicular protein trafficking.  Mainly functions in the early secretory pathway.  Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side (By similarity).
What are the official names of this protein?
Transmembrane emp24 domain-containing protein p24delta3, p24 family protein delta1a, p24delta1a, p24 family protein delta3, p24delta3.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Cycles between the endoplasmic reticulum and Golgi via COPI and COPII dependent pathways. Mainly located in endoplasmic reticulum.
Protein: MUTS_SYNS3
Sequence: MALQGNLFGDAEPASSAPSKGQKRQDEPDQLDDHELTQDAKQRPRQRQGQQEHSEPSASSQSEEAHSEASTPAGKDQDNSDDDLPPWSHHSQVTPEQLTPMLRHYVELKAAHPERILLYRLGDFFECFFEDAIHLSRLLELTLTGKEAGKQIGRVPMAGIPHHAAERYCSELIRRGLSVALCDQLEAAPASGSAKGTLLRRDITRVLTPGTVLEEGLLSARRNNWLAAVVVEPAQGRQPFRWGLACADVSTGEFLVREQDNSAALHQELARLDPAELIHHNQNSVAPSWCPERLQRCDIGNTPFSQPEAEALLLERFRLQTLDGLGLQNVPLAMRAAGGLIAYLGETCPLDDNGITPPPLERPITCFPGDALVLDAQTRRNLELIATQRDNQFQGSLLWAIDRTLTAMGARCLRRWIEAPLMDPSIIRSRQASVSQLVSKRPLRQALRRLLRPMGDLERLAGRAGAGHAGARDLVAIADGLERLPQLANLITSQLDGGPSWLSDVLEPDPALAVIGASIRHQLMDNPPLSLSEGGLIHDGVDPLLDGLRNQLDDQESWLAEQEQLERQSSNNSNLKLQYHRTFGYFLSVSRARSGAVPDHWIRRQTLANEERFITPDLKAREGQIFQMRARAAQREYELFCELRGQIGEHAEAIRRSARAIAGLDALTSLAEAAATGGWCAPEITADRSMVIEQGRHPVVEQLLVEDAFTPNDSNLGTGIDLVVLTGPNASGKSCYLRQIGLIQLLAQIGSWVPAQAARIGIADRIFTRVGAVDDLAAGQSTFMVEMAETANILHHASERSLVLLDEIGRGTATFDGLSIAWAVSEHLAGDLQARTVFATHYHELNALAGERSNVANCQVLVEETGSDLVFLHRVAAGGASRSYGIEAARLAGVPASVVQRARQVLDQLAT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: KUP_SALSV
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTGMVGKLFAPIMLTWFLILAVLGLRSIIANPEVLHALNPVWAVRFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPDWALIPLLILAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWLLYFAVVVVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARKNWHWNKYFVALILIAFLCVDIPLFSANLDKLLSGGWLPLSLGLIMFTIMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRALSVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLIVGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROB_CUPTR
Sequence: MITLEVDLGERSYPIHIGSGLLDNAELLRPHVRGQHAVIVTNETVGPLYAARVEQALAALGKTVRTVTLPDGEAFKHWETLNRIFDALLQAGADRKTTLVALGGGVVGDMTGFAAACYMRGVPFIQMPTTLLAQVDSSVGGKTGINHPLGKNMIGAFHQPNAVIADIDTLRTLPPRELAAGMAEVIKHGAIADADYFAWIERNIQALNACDPELMAVAVQRSCEIKAGVVAQDEREGGLRAILNFGHTFGHAIEAGMGYGAWLHGEAVGCGMVMAADLSHRLGFIDIETLARVRTLTQAAMLPVVAPELGADRYIELMKVDKKAEAGSIKFILLKKLGEAFITSVPDADLRATLAHAVLKPPTEAPVA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PC_STAS1
Sequence: MQKSADKSLKDRYLDLLSQQFNTKEELATEIINLESILELPKGTEHFVSDLHGEFHAFQHVLRNGSGNVRSKINDIFQDTLTRKEINEFSALVYYPEEKLKIIKNSFSSKSELNEWYITTINRLIKLITYASSKYTRTKLRKSLPKNYVFIIEELLYKSNKYNNKHSYYETLINQIIELEQSDDLIIGLSFTVQHLVVDHLHVVGDIYDRGPEPDKIMETLIDYPSVDIQWGNHDVLWIGAYAGSKVCLANLLRICARYDNLDIIEDAYGINLRPLLTLAEKHYDGKNKAFRPKNAEGLTELELEQITKIHQAIAIIQFKLEAPIIKRRPTFEMEERLVLESINYEKNEATLYGKTYPLENTCFQTIDPNGPNKLTDEESEVMDKLLLSVQQSEKLKRHMTFLMQKGTLYLPYNGNLLIHGCIPVDENGEMESMVINDVKCYGRDLLDHFEDYVREAFDHKDIQDDLATDLVWYLWTGKYSSLFGKRAMTTFERYFIKDKTAHKETKNPYYHLREDVNMCKKMLKDFGLDPEQGHIINGHTPVKEIDGEDPIKAEGKMIVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHQHFNSKKHVLLNGADELSIRRVVDKELQRQKIRHTNTGQDIQEKIDILKELMHDRYVN
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: COQ9_ASHGO
Sequence: MFRVCRRLYHPNTLEHAVGNRLRPLAYEQDSPQYKVLQRALEAHVPVLGFNERAIVRAAGDLGYGSAVLSALAAPNSPALLNVPSAVLELVKFHLVTKRVALADAAAQGNVSMEQLFLQRVEADRPLAGQLTQLLSILSLPGEFLVNTAMPELFRLSDDLIYYSGEKDHPDLAWYSKRAAVAMAYVSTNLFMARDRSPALEETLHFARRRLQQVDSLGTAYNNVEEFAWYQLLMAMNLVKSQLTRG
What is the function of this protein?
Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COQ9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPA_RHOP2
Sequence: MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLETDNVGVVIFGADREIKEGQTVKRTRSIVDTPVGKGLLGRVVDALGNPIDGKGPIQATERKRVDVKAPGIIPRKSVNEPMATGLKAIDALIPVGRGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPEGQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDPAPMQYIAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDHGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDASTQRLLNRGARLTELLKQPQFSPLKMEEQVVVIYAGVNGYLDALPVAKVRAFEDGLLSLLRGKEVGILDAIRTSRDLSDDTAAKLKAVVESYAKTFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TGT_HALH5
Sequence: MAAVTYELIKTCKQSGARLGKLHTPHGTIETPIFMPVGTLATVKTMSPEELKQLGAQIILSNTYHLWLRPGHDIVKEAGGLHEFMNWDRPILTDSGGFQVFSLSDLRTIEEEGVHFRNHLSGEKLFLSPEGAMEIQNALGSDIMMAFDECPPYPAERDYMRPSVERTSRWAERCLKAHKRPEDQALFGIIQGGEYEDLRRQSAQDITSLDFPGYAIGGVSVGEPKDVMNRVLEFTTPLLPANKPRYLMGVGSPDSLIDGAIRGIDMFDCVLPTRIARNGTCMTSNGRLVVRNAKYARDFRSLDENCDCHVCQTYTRAYIRHLVKCDETFGFRLTTYHNLYFLLKLMKDVRQAILDDRLLDFREEFFEQYGFNQPNAKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: YQHG_BACSU
Sequence: MRQQEVHDFLLRFFQANSCQIVDQGLGYMTVQLTVEMDKQIMNRPFYWHWREKTGGDPNPMKITFITDKENAPKDLDGEFIYFGAPRLFQIFKAVKQNGRFTRMYEKIESAGAKVPLQPWLGINVTISYQSDMKKDKLLSLGLHLVSGTIIEDFQSKLTQFSLTSQICDYCFTISPMIKPESGLKRMENYISKSAMQEPSDWAEQAVNRWKNDMTLLDKFYEHIEEKPEEYHLEKQALKTLYQPKISVEIENGGLFYLQNNISS
What are the official names of this protein?
Uncharacterized protein YqhG.
Protein: HIS4_LEPIC
Sequence: MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLGVNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNYGKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNLEAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISSI
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS7_HUMAN
Sequence: MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, Proteasome 26S subunit ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with TRIM5 in cytoplasmic bodies.
Protein: ZFAN4_MOUSE
Sequence: MFKADLGRIGIQLHTTYSRRIRKVKVMDNRKEPPFFNEDNVGPFYFKLPFYDTMELFIETLTGTCFELRVSPFEAVISVKGKIQRLEGIPICQQHLIWNNMELEDDYCLNDYNISEGCTLKLVLAMRGGPISTRKVPVEDPLRELAEYMDSSRDEVWEKTSCNKQVTFLVYREGDQLNFFRVVDRGDGTLTPLSESLSGSVYNLYTDEDEEAEPSPSGQQIIENSITMNKMKLLKAKMENMNLSKKPKKVVKVKPRPPLAPRPTSSSTAAARHRLLRVLPHIGQSCLPSGNAHLPETSRNAGPSPAAQAPADRPVSSLRNELLKDDDNWEINMLSHSTSSIRLLPQLTHIELESDKELADSVLHLGSSLSRRTKHLSGNLLSNNEDDVVLFPRSEECVADELLLPEVGAFAPFAEGTGAEQSSGVEGLGKVTPEFPLTKGDGGLRAAEQPLSHVARVLSSEPGDNAVLNHREPSSHKNRLLSPLLCAAPVSLHNSLVKPQRQSKCFESGNPSASTSQNTLRELDIRTIADSSFSRTARFRGVKVDSPGKRSDIISKVEARDITEMANKASKEPVGCVNNNGFLASLARSASRDSLQSTHGACRLRSSGIGLSTNFQHFQDENIRKSSPQSEPTDFFLSARGIGMSGSNAAAGKRIGESIHHLPPVKAPLQTKKKIMKHCFLCGKKTGLATSFECRCGNNFCASHRYAEAHGCTYDYKSAGRRYLEEANPVVNAPKLPKI
What are the official names of this protein?
AN1-type zinc finger protein 4, AN1-type zinc finger and ubiquitin domain-containing protein-like 1.
Protein: SYK_CHRSD
Sequence: MANQDAAQHDENHLIAERRAKLAARRDQAAEAGGSAFPNDFRRDSLAAELQAELGDKDKAELETLDRRASVAGRIMRKRGPFIVIQDVSDQIQLYVDKKGLPAETLDDIKSWDIGDIVAARGPVHKSGKGDLYVMMGEAQLLTKSLRPLPDKYHGLTDTEARYRQRYVDLIMNPESRRVFEVRSRVISGIRRFLVERGFMEVETPMLQQIPGGATARPFVTHHNALDIDMYLRVAPELYLKRLVVGGFERVFEINRNFRNEGLSTRHNPEFTMLEFYWAYADYRDLLDLTEAMIRDVAHEVLGTTTVEYQGARYELGEPFQRLTLRQSILEYGDGLGESDIDTFDGARATCERLGIPVKPSWGLGKLQTEIFEAVAEDKLDRPTFITEYPAEVSPLARRNDTNPHVTDRFEFFVGGRELANGFSELNDAEDQAERFAAQAAEKDAGDLEAMYYDADYVRALEYGMPPTAGEGIGIDRLVMLLTDSPSIRDVLLFPAMRPSAD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATND_EMENI
Sequence: MANPERSYLSRFFSSQFSKLPYPSQSFKDAVILVTGGNTGLGLEAARHFVRLQAATVILAVRDLKKGEQAKLSIEESTKVQGVVEVWQVDLEDVRSVQSLAAKASSLPRLDVVVANAGISTNKWALVGDMERTIQVNVLSTFLLILALLPKMQEQDIEGQIRARPRVVVVSSEGHETTAFAERKAARIFDALRDQRQANMDERYDTSKLIQLYLVRALAERLSRSDKPPVTLNAVSPGLCKTGLLRETPLVARLLTGPVMAILARNAEEGSRTLVHAAAANDGETNGKYLRDYLQRLYAAKKATPRRRDCCRSF
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of aspercryptins, linear lipopeptides built from six amino acids including 2 highly unusual and nonproteogenic amino acids, 2-amino-octanoic acid (2aoa) and 2-amino-dodecanol (2adol) (PubMed:23248299, PubMed:27310134, PubMed:26563584).  The core structure of aspercryptins is as follows: Ser/Ala-Thr-Ile/Val-2aoa-Asn-2adol (PubMed:27310134).  The first step of aspercryptin biosynthesis is the generation of the fatty acid precursors, octanoic and dodecanoic acids, by the FAS subunits atnF and atnM (PubMed:27310134, PubMed:26563584).  The fatty acid precursors are likely transformed into the corresponding alpha-amino fatty acids in three steps (PubMed:27310134, PubMed:26563584).  First, they are hydroxylated by the cytochrome P450 monooxygenase atnE, then oxidized to the corresponding alpha-keto acids by the NAD(P)-dependent oxidoreductase atnD, and finally converted to the alpha-amino fatty acids by the PLP-dependent aminotransferases atnH or atnJ (PubMed:27310134, PubMed:26563584).  the alpha-amino fatty acids, 2-amino-octanoic and 2-amino-dodecanoic acids, are recognized, activated, and covalently tethered to the NRPS atnA by its fourth and sixth adenylation domains (PubMed:27310134).  The second module of atnA is the Thr module and contains an epimerase (E) domain responsible for the epimerization of Thr to D-allo-Thr (PubMed:26563584).  Additionally, despite atnA having only one epimerase domain, the first amino acid of aspercryptin A1 is D-Ser, suggesting that serine is either loaded directly as D-Ser on the first module or that the epimerase domain in the threonine module epimerizes both L-Ser and L-Thr (PubMed:27310134).  After condensation of the hexapeptide of aspercryptin, the C-terminal reductase (TE) domain might be involved in the reductive release and production of the aldehyde hexapeptide (PubMed:26563584).  Further reduction would generate aspercryptins (PubMed:27310134, PubMed:26563584).  The variety of aspercryptins produced reflects the flexibiliy of the atnA NRPS, allowing incorporation of alanine instead of serine, valine for isoleucine, and a C10 fatty amino alcohol instead of the C12 version (PubMed:27310134).  AtnB seems to be involved in the selectivity for Ile versus Val by the third module (PubMed:26563584).  Moreover, type B, C and D aspercryptins have an additional N-terminal cichorine, acetyl and propionyl group respectively (PubMed:27310134).
What are the official names of this protein?
Short chain dehydrogenase atnD, Aspercryptin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: Y3974_BACC7
Sequence: MGFPKVERLLINYKTLDEFKKFKGCGAQELSMLEELQANIIENNSESPFYGIYYGGSLIARMSLYMKRNGGEPFEITGTYLELYKLEVLPTFQKQGFGEMLVNYAKGLQFPIKTIARIHSAGFWDKLNFQPVSVPDGDFYVWHPETNLNAVTNEESA
What are the official names of this protein?
Uncharacterized N-acetyltransferase BCAH187_A3974.
Protein: PMP2_YEAST
Sequence: MLMSTLPGGVILVFILVGLACIAIISTIIYRKWQARQRGLQRF
What are the official names of this protein?
Plasma membrane ATPase proteolipid 2.
What are the subcellular locations of this protein?
Cell membrane.
Protein: MYOM_DICDI
Sequence: MKHLEGDIVWVPHTVNGYCRGKIIGYNEKNQVTVRLLELNEEIKINEQLIQNYNQSDDKDFSDMVEIQDLSEAIILNNLGLRYKSDQIYTYIGNVLISINPYKEIKDIYSLNILNKYKDINTIKSNPPHIYAVALRAYQSMVSEKKNQSIIISGESGSGKTEASKTILQYLINTSNSNSNNNTNINNNNNSIEKDILNSNPILEAFGNSRTTKNHNSSRFGKFLKIEFRSSDMKIDGASIETYLLEKSRISHRPDVNNLSYHIFYYLVMGASKEERERLGLDNDPSKYRYLDASTSVIESFKKQSNGGSGGGSGNNDLSESLQLVKQSLESMSIAKEQCDDIFLTLAAILHLGNIEFEVDQTENEQTSGFSKISEQKASVKKSLSMVSKLLGYPEQVFKQTLLNRNLKGGGRGSVYCRPMEVYQSEQTRDALSKALYVRLFASIVEKINVKFIQNTGSKDLQGGYSSKRNNLFIGVLDIFGFENLSSNSLDQLLINFTNEKLQQQFNLNVFENEQKDYLQEGIPWSTSNFIDNKECIELFEKKSYGLLSLLDDECMMPKGSEVTLLEKYNKQYHNTNQYYQRTLAKGTLGIKHFAGDVTYQTDGWLEKNRDSIPTEVEQLLSASSNNLIKSLFNLKELNKSNDNNSNNNNSNNNSSSSSSSQSTASITAKASPPRERFNSGSGSGTTSPLNLSGSSSPLSGSGSYSIIGGNSNSNSNNNNSSNNKKSQSVSVAGQFIEQLNKLISTINSTSVHYIRCIKPNVTMDCNNFNNSHVLSQLRNVGVLNTVKVRKMGYSYRRDFIQFYSRYNCILNSLNIKINLTNINHSNLCKEILENVNSQYKNNNNNKNNNNQIVKITTNSKPTFQIGKTKIFISDELYIYLEKKRYDSLVDSVLKIQAFFKMIKIRNQYKRNKESSLFLQTLIRAQRAKKDFEQLVILENKRKEEERKKELERQRKEEEERQKELERQRREEEKELERKRKEEERELERQRKEEEKEQERKRKEEEKEQERKKKEEKEIEKKRKEEEKKKKKNEQNLSLPSLDITNSPSLINTTTTTTTTTTTTTNTSSPPLSPPISPRPSTPSSTSSSSSTTSSPSTKKQLLFKFNSISNLLSKSLHGSSHSDKNSKEDNNSNNNNNGDSTIILSSDSSFGQPTPKATSTPTPPPPPPLKTQPVPISSGVENNSSPNLWSHRNSPNFNGLVREKSRARIGRLTIRSASPLDLTYLPDPSKNEGSPQFTSQSLDFTPNIPPIITNSIVEQQSSLSGINKPIPQRTISSSENSPLSRANSSISSSLLILTPTLTSLSTSTTPSTPTTPKTPTTLSSSSVSTSTSLSSVSSSVSSSSSSSIPTPIIESTPSNSNEDLITTLSSPISTGHTGESIEEKNKRFRIKIINELIETERDYVRDLNIVVEVFLNPIREKQLLSAKDINSLFSNIEILFSINMNVLKALEKDKDPLCENISVGQTFLDMSHYLKMYTTYCSNQQNALKILEEEKIKNQPFREYLEFCMNDSVCRGLPLNSFIIKPVQRICKYPLLIKETIKFTPNDHPDKPALEEVDKKISDIVQSINEAKRTLELFQKIVDLQNSIDGLEDTNLMEQGRTLLMEGTVSAVKELNSEDSLSRTLFLFNNLILICSFGTNVLSTAINQFKTKKLKLKAKIPISDSRLIFVSDTDSVKYALEIVNIKEDSNYILCFNNDQDRSKWFKQIKALIQEQKLSNAKKAATIGNSRLIQTTS
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Involved in macropinocytosis and remodeling of actin cytoskeleton.
What are the official names of this protein?
Myosin-M heavy chain, RhoGEF domain-containing protein myoM.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Enriched in actin cortex regions.