PharMolix/UniProtQA huggingface dataset:
Protein: CHRY2_GIBZE
Sequence: MCGISAFITHPGHSRSPVLNGDAKQVVEELETSLDLIAHRGPDARGRWFSDNHHVGLGHVRLSIIDLSPSGNQPFHDEQGGIHAVVNGELYDYERYKAQLADEFKFVGNSDCEIVIALYKHYGLSFISHLRGEFAFVLWDENRQQLIAARDRYGIKSLYYTVHQNKLLVATEIKSFLAFGLEPEWCVRSLRDQSWRVDSTTFFEGVYKVRPGHYLICRPNEREEQHPYWDLEYPDKFAKDLRSEDEITEGVRERLLEAVRIRLKADVPVAVYLSGGIDSSSVAGMVSHLIKQGTKLGNETSLLPSSMKCYTVQFDEGSGADESAIARRTADFLGVDIHLVKMDEEALVSRFEDTTWYSEVPLPDLNGMGRLALAEAVHAQGIKAVITGEGSDEHFGGYDAFRADSLSEPDHSWPAMMTDTERQEAHALASKEAQYGIFGDFTPKVPISTKRMFYSNHVASSIARVGSLPFSDWTKVYGNSIPETTMIEGFDGRVRDNILKRWHPVHTAQYMFVKTFMPHFILRYNGDNIDMVHQVESRCPFLDHHLTEYVNNVPPSLKMRYNAKDKSWREKHILREAVKPFVTDEVYNMSKKAYMGPRKFWPGGPLHKKISELVTKANVENLGFVDWQATQDAMDGAFNKQEGLALRRIITVAQFVVLGQRFGVKRASGRR
What is the function of this protein?
Amidase; part of the gene cluster that mediates the biosynthesis of the yellow pigment chrysogine (PubMed:28708398).  Pyruvic acid and anthranilic acid are likely substrates for the nonribosomal peptide synthetase chry1/NRPS14, with pyruvic acid adenylated by the first A domain and anthranilic acid by the second (Probable).  If pyruvic acid and anthranilic acid are merged and released from chry1/NRPS14 by hydrolysis, a subsequent amidation would lead to 2-pyruvoylaminobenzamide (Probable).  This process is probably catalyzed by the amidotransferase chry2 using glutamine as amino donor (Probable).  The dehydrogenase chry5 that has a terminal berberine bridge domain for C-N cyclization could catalyze the cyclization of 2-pyruvoylaminobenzamide to yield acetyl-4(3H)-quinazolidinone (Probable).  A final reduction of acetyl-4(3H)-quinazolidinone catalyzed by the oxidoreductase chry4 would result in chrysogine (Probable).
What are the official names of this protein?
Amidase chry2, Chrysogine biosynthesis cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the asparagine synthetase family.
Protein: METE_BACCQ
Sequence: MAIQTSNLGYPRIGLQREWKKTLEAFWSNKIDEEQFLTTMKEIRLKHVKAQQEKGIELIPIGDFTYYDHVLDTAYMLGFIPSRFSEFTSYLDVYFAMARGSKDHVASEMTKWFNTNYHYIVPEYEEGLQISLKDNRPLRLYEEAKQELGVDGKPVILGPYTFLKLAKGYTQEQFATILKQLVAPYVQLLSELHAAGAQIIQVDEPIFASLTKEEVQQAKEIYEAIRKEVPNANLLLQTYFDSVEENYEEIITFPVSSIGLDFIHGKEGNLHAISKYGFPADKTLAVGCIDGRNIWRADLDEVLTLFTTLQKQVQTKNFIVQPSCSLLHTPIDKTEETHLSTELFDALAFANQKLEELVLIHSALTQGTESIRNELETYRNVHHTIRSSAARNREDVKAARTALKEEDFSRPLPFEKRYELQQVALKLPLLPTTTIGSFPQTTEVRQTRKEWRNGVISNEQYEQFIEKETEKWIRYQEEIGLDVLVHGEFERTDMVEYFGERLAGFSFTKNGWVQSYGSRCVKPPVIYGDVAFINGMTIKETVYAQSLTEKVVKGMLTGPVTILNWSFVRNDIPRKEVSYQIALALRHEIELLESSGIRVIQVDEPALREGMPLKEKDWDAYITWAVQSFLLATSSVANETQIHTHMCYSNFEDIVDAIRALDADVISIETSRSHGEFIDTLKHTTYEKGIGLGVYDIHSPRVPSKDEMYKIVEQSLKVCDPKYFWINPDCGLKTRRTEEVIPALEHMVQAAKDARSLLKTNA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: MBTL_MYCPA
Sequence: MPAGSPENHVSAELLGILRDDLNVDVSRVTPDARLVDDVGLDSVAFAVGMVAIEERLGVTLTEEELLSCETVGDLQAAIAAEPRETRDE
What is the function of this protein?
Acyl carrier protein involved in the formation of acyl-S-ACP intermediates within the mycobactin biosynthesis process.
What are the official names of this protein?
Acyl carrier protein MbtL, ACP, Mycobactin synthase protein L.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPEP2_PAEA2
Sequence: MKWDKRVVALILAVMIVCPLFAAPAHAQEQSILDKLVVLPSGEYNHSEAAAMKQRLEKIPTSILDALYSKGVKIKLTQGAITNEPELAYLKGVVPRGWEGTGLTWDDVPGVSERVVAVRIGYSEKGKGHNSLNLEIHETLHAVDRLVLNEVSGTDEFINIFNKEASVKYKGDGYVSAYPTEYFAEAASLYLYSDATRSDLKDSMPLTYEFMAKLFAN
What is the function of this protein?
Zinc-dependent endoprotease with a unique preference for proline residues surrounding the scissile bond, which cleaves in a PLP-|-PVP motif.  Cleaves the cell surface protein encoded by an adjacent gene, which contains two PPEP-2 cleaving sites and putative extracellular matrix-binding domains.  Thereby, may have a role in the regulation of P. alvei adhesion.  Is not able to cleave within the PVP-|-PVQ motif, and only shows a very poor cleavage of the VNP-|-PVP motif in vitro, which is the optimal substrate peptide for PPEP-1 from P. difficile.
What are the official names of this protein?
Pro-Pro endopeptidase, PPEP-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M34 family. Pro-Pro endopeptidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_MYCSS
Sequence: MAIRKYKPTTPGRRGASVSDFAEITRSTPEKSLVRPLHGKGGRNAHGRITTRHKGGGHKRAYRVIDFRRHDKDGVDAKVAHIEYDPNRTANIALLHYLDGEKRYIIAPYGLKQGAIVESGANADIKPGNNLPLRNIPAGTVIHAVELRPGGGAKLARSAGVSIQLLGKEGSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRMRWKGKRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWGKPEGRTRKPNKPSDKLIVRRRRTGKKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS18_CHLTA
Sequence: MNRPVHNEHRRKRFAKKCPFVSAGWKTIDYKDVTTLKRFITERGKILPRRITGVSSRFQALLAQAVKRARHVGLLPFVGED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RECU_LACDB
Sequence: MVKYPTGSVMPLRAAQRQGKKALLKKASFSDRGMTLEQQINESNQYYLDAGIAVVHKKPTPIQIVKVDYPKRSRAVIREAYFRQASTTDYNGVYQGYYLDFEAKETRNKTSFPLKNFHEHQILHLEQCLDQEGICFALIGFMTLERYFVTPASFLIQAWQNWKAAGKSSMTLAEIEANSFEIKSGFCPALPYLEAVDRIIADRKQEHGNK
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_RICB8
Sequence: MSKKLENIRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATTCRWQDKQINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRMCFVNKMDRMGADFYRCVDMIKDRLGAKPLVIQLPIGIEENFKGVVDLVKMQAVVWKDESLGAEYSYQEIPDDMKAKAEEYRANLLDMVVELDDKIMEKYLSGEEVTEEEIKKLIRKGTISAAFYPVLCGSAFKNKGVQPLLDAVVDYLPSPIDIATVKGVEVSTGEEKDFPISVSEPFSALAFKIMNDPFVGSLTFIRVYSGKITSGTTVINTVKNKREKIGRMLLMHANNREDVKEASAGDIVALAGLKDTTTGDTLSDEDKKVILERMEFPEPVIELAVEPKSKVDQEKMGLALSRLAAEDPSFRTSTDQETGQTVIKGMGELHLEIIIDRMRREFKVEANIGAPQVAYRETITKACEIDYTHKKQSGGAGQFARVKIIFEPLKDVKDLKEEDKNKSFIFESKIVGGAVPKEYIPGVEKGLNNIRETGVIAGYPMIDFKATLIDGAFHDVDSSVLAFEIAAKAAFREGMPKGNPKLLEPIMKVEVITPDEYMGDVIGDLNSRRGQVQGMEPRGNAQVIKAYVPLAEMFGYVNTLRSLSQGRAQYSMVFNHYDQVPTQVADTIKAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTD_ENT38
Sequence: MKISLSPPPFADAPVVVLIAGLGGSGSYWLPQLAALEQEYQVVCYDQRGTGNNAGELPHGYTLGNMADELYQALLNAGIPRFTVIGHALGALVGLQLAIAHPDAVRALVCVNGWLSLNAHTRRCFQIRERLLHAGGAQAWVEAQPLFLYPADWMAARAPRMEAEEALALAHFQGTNNLQRRLLALKQADFRAQAKHVHCPVQIICSTDDLLVPSVCSTELHAALPGSHKTVMRQGGHACNVTDPDTFNALLLNGLASLMHNPEPVFKESQ
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: Y1034_THEMA
Sequence: MIRVLSVFGTRPEAIKMAPLVKKLEEEQNVESLVCVTAQHRQMLDQVLEVFDIKPDFDLNIMKERQNLSDITVNALSGLYDLIGELKPDIVLVQGDTTTTFAGALAAFYHRIPVGHVEAGLRTNDRYSPFPEEINRRLTGVLSTLHFAPTKRNRENLLKENVMGKIYVTGNTVIDALRYTVKENHVFEDPILRNMDFSDGRYILLTSHRRENIGKPLENICRAVRRIVEGFEDVKVIYPVHMNPAVREIVFPMLENVERVFLIDPVNVIDMHNLMARSYLIMTDSGGIQEEAPALGKPVIVLRKETERPEAIEAGVAVLGGVEEERIFELAKKLLVDREEYEKMAKAVNPFGDGRASERIVKAILHEFGLSDPPEEFC
What are the official names of this protein?
Putative UDP-N-acetylglucosamine 2-epimerase, UDP-GlcNAc-2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_SHEWM
Sequence: MKDSVIRKLEGLLERNEEVLALLSDPSVIADQERFRALSKEYSQLEDVVKSFTAFQQATEDLEAAKEMLNEDDPELKEMAQEEMKEAKSVLETLEDELQILLLPKDPNDDNNAFIEIRAGAGGDEAAIFAGDLFRMYSKYSESNRWQIEVMNTNEGEHGGFKEVIAKISGEGVYGKLKFESGGHRVQRVPETESQGRVHTSACTVIVLPEIPEAEAIEINKADLKVDTFRASGAGGQHVNKTDSAIRITHIPTGIVVECQDQRSQHKNRAQAMSVLSARIQAVEDEKRRSEEESTRRNLVSSGDRSERIRTYNFPQGRMSDHRINLTLYRLNEVMEGVLDVIIEPLILENQADLLAALAED
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_STRTD
Sequence: MARILDNDLLGDEEYVERTLRPQYFKEYIGQDKVKDQLKIFIEAAKLRDEALDHTLLFGPPGLGKTTMAFVIANEMGVNLKQTSGPAIEKAGDLVAILNDLEPGDILFIDEIHRMPMAVEEVLYSAMEDYYIDIMIGAGETSRSVHLDLPPFTLVGATTRAGMLSNPLRARFGINGHMEYYELPDLTEIVERTSEIFEMTITPEAALELARRSRGTPRIANRLLKRVRDYAQIMGDGVIDDKIADQALTMLDVDHEGLDYVDQKILRTMIEMYGGGPVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRTGRVATAKAYEHMGYDYTRDN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MT4A_ORYSJ
Sequence: MSCCGGSCNCGSSCKCGSGCGNMYPDLAEKTTNTSATMVLGVAPAKEQFEGVGKAAESGEAAHGCSCGSSCKCNPCNC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 4A, Class I metallothionein-like protein 4A, OsMT-I-4a, OsMT1b.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: DER_RHOPS
Sequence: MSFTFAIIGRPNVGKSTLFNRLVGQKLALVDDTPGVTRDRREGEGRLGDLEFTIIDTAGLDEGAKGSLTARMQQQTETAIELADALMFVFDARAGLTPNDRAFADFARRANKPVVLVANKSEGKAGEIGAMESYALGLGDPVQISAEHGEGLSELYDALRALMPEPDVELEDDEEIDGLTEEDFSKRPIRVAIVGRPNAGKSTFINRLLGEDRLLTSPEAGTTRDSIAVEVNWKGRDFRIFDTAGLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMMDSQNRFEEQDLRIADLIEREGRALVIAVNKWDLVERQGGQIAQLRTDADHWLPQIKGVPIVATSGMLGEGVDRMMEAIQDAYAVWNTRVPTAALNRWFEQAVAQNPPPAVAGRRLKLNYVTQTKARPPSFVVFCSRADAVPQSYLRYLVNSLRGVFELPGTPVRIMLREKANPFAHKRKRKS
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RS16_STRLI
Sequence: MAVKIKLKRLGKIRSPHYRIVVADSRTRRDGRAIEEIGKYHPTYNPSVMEVDAERVAYWLGVGAQPTEPVLAILKKTGDWQKFKGEPAPAPLLQPAEKAARPSFEAIGGEDEGKGEAITQKKKADKRDEAAAESSASEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y16A_UREPA
Sequence: MNKIIKFHNERIKWLWILTAILAISFFVICFNNVKWIYTENTAKYELLTSSLEKIVKFYSFSLVDKPFARGVPNSIDVFSRAIIGVAFGLGFVGTMLIDYFIISKVAYIVKQKIKQSKKVGM
What are the official names of this protein?
Uncharacterized protein UU165.2.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDD_BACC1
Sequence: MKQIFIGIIRFYQKFISPMTPPTCRFYPTCSHYGLEAFQKHGALKGFWLTCKRILKCHPFHPGGFDPVPDKKDDKVHS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PTM3C_BUCAP
Sequence: MFRLITLKIQNFGQFLSNMIMPNISIFITWGIMNSLFLSLDWQYNKIFAQLISPIIFYLLPILIGYTGGSLIAGQRGGLLGSITTIGMITSTDMPMFLGGMVAGPLGGWIIKGFDQIIKNRIKSGFEMLVNNFSIAIIGIFLTIFSFFFIGPFIEGVSKFLGCLIKIIIDFNLLPLIAFIIEPAKVFFLNNAINHGIFSPLGIQEISENKSSLFFLIESNPGPGLGILIACFFFGKEKSYKSSGTAAIVQFLGGIHEIYFSYVLIKPILMISLILGSMTSIFMLVFFKGGLIAAVSPGSILSILAMTKKGLYFANLISIFSSFLISFLSAMLFFKINLGQKIKNDKSSIQLFKNNLFPIKKIGDEKYDFIKKIKNFQKIKNIIIACDAGMGSSAMGASILRKKIKSNNLTHIYVSNIAINLLPKNADLVITHEKLTYLAKKRAPDAQHISLTNFLDSNFYTSLVKQLDLNKDFFKKNNIQDKKDRITQINIDSHKEIQSKCFFQISDKNIFLNQYAENKKEAIKIVGKHLVAQGYVKKDYIDAMLDREKIASTWLGESVALPHGTIKSKDSILKTGVIFCQFPKGVHFGETIDDIAYLVIGIAAKNNEHIMVVSNITNALDDKDVISKLSKTKSVKEVLSYLNVNVKKN
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICBA component, EIICBA-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIG_THIDA
Sequence: MQGNLEVLEGLARRLDISVPVDQLETEVQSRLKRLARSVKMHGFRPGKAPLSAVARQHGAGVRQEVLGETLKTRFGEAVQTHQLRIAGYPRFEPKADASAAAEMTFSASFEVYPEVKIDALDSATLNRPVVELGDADVAKTLEVLQKQRRTFATAARAAAEGDLVKFDYQGTVDGAPFEGGRGEDFAAVIGEGRLLKDFEQALVGLKAGDSKGFDLTFPAEYAARELADKTAHFEVQVKEVQAPVLPPVDAEFAEALGVEDGDVEKLKAEVKSNLEREVKRRVQAKLKEQAMELLLQKSTLDLPRSLVEMEMDRLRRMTEADMQSRGVQSMKLSADMFTGQAERRVRLGLILAEIVQANKLAAQPEQIRSLIQDQAQSYEEPDQVVQWYYQSPERMQEIESLALEENVVAWVADQATVVDVATSFDELMGRA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ENKUR_MOUSE
Sequence: MDSPCTSESIYNLIPSDLKEPPQHPRYTSLFRATIKNDMKKFKTAMKTMGPAKVEIPSPKDFLKKHSKEKTLPPKKKFNRCSPKKPAVPLRTDHPVMGIQSGKNFINTNAADVIMGVAKKPKPIYVDKRTGDKHDLETSGLFPKYINKKDYGITPEYICKRNEDVKKAQEEYDNYIQENLKKAAMKRLSDEEREAVLQGLKKNWEEVHKEFQSLSVFIDSVPKKIRKQKLEKEMKQLEHDISVIEKHKIIYIANK
What is the function of this protein?
Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel (PubMed:15385169).  Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity).
What are the official names of this protein?
Enkurin.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Note=Sperm acrosomal crescent and flagellar principal piece.
Protein: PDXS_BIFLS
Sequence: MTQNRAELNRNLAQMLKGGVIMDVTTPEQAKIAQDAGACAVMALERIPADIRAAGGVSRMSDPAMIKGIQEAVSIPVMAKVRIGHIAEARILQAIEIDYIDESEVLSPADDVYHIDKNQFDVPFVCGAKNLGEALRRIAEGAAMIRTKGEPGTGDVIQAVRHMRTMNKQIRELVGLRDDEVYEAAKQLAVPYDLAKYVHDNGRLPVVNFAAGGVATPADAALMMELGAEGVFVGSGIFKSGDPAKRAAAIVKATANWQDADLLAKLSENLGEAMVGINEDEIQTIMAARGE
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: Y2585_DEIRA
Sequence: MSHTHFDLTALPQSARYKLLTATVVPRPIAWVGTRGSGETGKLGFNLAPYSFFGLMGSEPPVVAFAPGDRADGTPKDSALNIGSGGEFTVSLVSAALAAVMNLSATDFPRGMDEAQALGIQLAPGRRVQVPHVAAAPAALECREVQTVSIGRTRIILGEVLGLWLREDAVLDAEKHHVDTAALDLVGRMGGRGTYTHTRDTFELGRLTYAQWQEQWQAREEGDHSEK
What are the official names of this protein?
Uncharacterized protein DR_2585.
What is the protein family that this protein belongs to?
Belongs to the flavoredoxin family.
Protein: PSD_SYNC1
Sequence: MRNQNQPVAIEGYPFIGLFAFITLVFALLGWSVCTLLFLGLTLFAAYFFRNPDRYSDAEDAAILAPADGKVVYVGPALEERYFKSEVTKISIFMSVFNVHVNRVPMAGKVVDMFYNKGQFLNAAMDKASLHNEQSGMLLEHTSGRRMLVVQIAGLIARRIVTYPVVGDILQRGARYGLIRFGSRVDIYLEDDVDIQVTVGERVCCGETVLGFLK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y4852_PSEA8
Sequence: MAEFHDDDSQFEEKSKSQIKRELHALQDLGERLTTLQPQLLERLPLTDPLRKALLEAPKHKAHIARKRHIQYIGKLMRDQDVDAIVALIDQVDSSTRQYNERFHALERWRDQLIAGGDAALDAFVGEFPECDRQHLRGLVRHAQHEAAHNKPPAAARKVFKYIRELDETKRGLR
What are the official names of this protein?
UPF0307 protein PLES_48521.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RIMP_TRIV2
Sequence: MTHPLVPPITDLAIPVAEQLGLEVVGIVFHTNQRPPVLRVDIRNPQQDTGLDDCERMSRALEAALDATEIIPDAYVLEVSSPGISRQLVTDREFISFKGFPVIVSTSPPHEGQQEWIGQLIRRDETKVYINQKGRVIEIPRSLITRVLLHDGE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDI1_RAT
Sequence: MLITVYCVRRDLTEVTFSLQVNPDFELSNFRVLCELESGVPAEEAQIVYMEQLLTDDHCSLGSYGLKDGDMVVLLQKDNVGPRPPGRAPNHPRTDFTGSGSAVPGTSSSRHPHPHQHHHHQHQRIPSTQQAHGLASGENMAFAQDLNSPALIRSMLLSNPHDLSLLKERNPALAEALLSGNLETFSQVLVEQQRERAMREQEMFRLYSADPFDQETQARIEEEIRQQNIEENMNIAMEEAPESFGQVAMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGVAKGVGTQRIMGRVHLAQIQIEGDFLQCSFSILEEQPMDILLGLDMLRRHQCSIDLKKNVLVIGTTGSQTHFLPEGELPLCAKLLSGAVQEDSSDKEVAGSIKHPVKGPGRKKH
What is the function of this protein?
Probable aspartic protease (By similarity).  Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2.  Required, with DDI2, for cellular survival following replication stress.  Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (By similarity).
What are the official names of this protein?
Protein DDI1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
Protein: RL23_RHIL3
Sequence: MTDLRHYDVIVSPAITEKSTLVSENNQVVFNVAKQATKPEIKAAVEALFGVKVTAVNTLLRKGKTKRFRGFVGKQKDVKKAVVTLAEGQTIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: GLNA2_SOYBN
Sequence: MSLLSDLINLNLSDITDKVIAEYIWVGGSGMDMRSKARTLSGPVKDPSKLPKWNYDGSSTGQAPGQDSEVILYPQAIFKDPFRRGSNILVMCDAYTPAGEPIPTNKRNNAAKIFGHPDVAAEEPWYGLEQEYTLLQKDVQWPLGWPLGGFPGPQGPYYCGTGANKAFGRDIVDSHYKACIYAGINISGINGEVMPGQWEFQVGPSIGISAADELWVARYILERITEIAGVVLSFDPKPIQGDWNGAGAHTNYSTKSMRNDGGYEVIKKAIAKLEKRHKEHIAAYGEGNERRLTGRHETADMNTFVWGVANRGASIRVGRDTEKAGKGYFEDRRPASNMDPYVVTSMIAETTILWKP
What are the official names of this protein?
Glutamine synthetase cytosolic isozyme 2, GS1-2, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_THIDA
Sequence: MSNGKIVQIIGAVVDVEFPRDAMPKVMEALKMQAPELTFEVQQQLGDGVVRTIAMGSTDGLRRGMDVLSTGNPIMVPVGQKTLGRIMNVLGDPVDEAGPIGAETTMPIHRKAPAYADQAATVEILETGIKVIDLIMPIAKGGKVGLFGGAGVGKTVTLMELIRNIAVQHSGFSVFAGVGERTREGNDFYHEMKEGGVLDKVALVYGQMNEPPGNRLRVALTGLTMAEYFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLADEMGRLQERITSTKTGSITSFQAVYVPADDLTDPSPATTFAHLDATLVLSRQVAELGIYPAVDPLDSTSRILDPQVVGEEHYTVARKVQGTLQKYKELRDIIAILGMDELSPEDKLAVSRARKLQRFLSQPFFVAEVFTGAPGKYVTLKDTIAGFKAIVEGEYDHLPEQAFYMVGGIEEAVEKAKTIQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.