PharMolix/UniProtQA huggingface dataset:
Protein: CPNA_COMS9
Sequence: MGRVNDKVVLVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEPMRKAHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVIATPMTQQILDAPQSARALLGPTLLGRAAQPMEVSQAVLFLVSDEASFVHGSELVVDGGYTAN
What is the function of this protein?
Catalyzes the oxidation of cyclopentanol to cyclopentanone and cyclohexanol to cyclohexanone.  The activity toward cyclohexanol is 60% that of cyclopentanol.
What are the official names of this protein?
Cyclopentanol dehydrogenase, Cyclohexanol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: WECB_ECO57
Sequence: MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLDQVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLRENVADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESFGRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVEEVTRLLKDENEYQTMSRAHNPYGDGQACSRILEALKNNRISL
What is the function of this protein?
Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
What are the official names of this protein?
UDP-N-acetylglucosamine 2-epimerase, UDP-GlcNAc-2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_PHEZH
Sequence: MPDRPVRTRIAPSPTGMMHIGTARTALFNWLYARHTGGKFLLRIEDTDRERSTDEAVKVIFDGLKWLGLDADEPPVFQFARADRHREAAETLLARGGAYRDYMTPEELEAEREVARAEGRVVRSPWRDASPNDAPDRPFVVRLKAPQEGETVIQDAVKGEVRFQNKQLDDLILLRTDGTPTYNLAVVVDDHDMGVTHVIRGDDHLNNAARQTLIYQGLGWEVPVWAHLPLIHGPDGAKLSKRHGAQAVSEFDSMGYLPETMRNYLAKLGWGHGDDEIFSDEQAIAWFDINDVVSAPARLDWAKLNHLNNHYIRQAEPARLAELVKTVLASRDWPLEAGDMAVIERTIPFVRDGAKTTLELADNVVFALKRRPLELPEKTRTQMTEELRGRLSRLREALAAVEYWDVPSLEAALRAFAEAEGVGLGKFGPQLRAVLSGGAPAPDLAGAMVALTRDESLGRLDDALSPSA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHI_ARATH
Sequence: MAGFFSLGHGGGGNTPDNHRTNTNNPSSSGTESWLWCRNPNSNADGGEAGPSYKGTLELWQHPNNQEIIFQQQQQQQQRLDLYTSAAGLGVGPSNRSLIETSGGALMMMRSGSGSGGPSCQDCGNQSKKDCSHMRCRTCCKSRGLDCPTHVKSTWVPAAKRRERQQQLSTGQQPQQLGGSVPKRQRERIPARSTSMAYTRIPSNNTSGLEVGNFPPEVSSSAVFRCVRVSSVDDEEEEYAYKTAVSIGGHVFKGVLYDQGPAERSSSGGGSQPLNLITAGPSASSSSPNVSCNNGVVGSTSDHYIDPASLNYPTPINTFMTGTHFFSNSRS
What is the function of this protein?
Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e. g.  YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering.  Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning.  Promotes style and stigma formation, and influences vascular development during gynoecium development.  May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM).  Suppressor of the gibberellin (GA) signal transduction.
What are the official names of this protein?
Protein SHORT INTERNODES.
What is the protein family that this protein belongs to?
Belongs to the SHI protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHT46_ORYSJ
Sequence: MKFPKRYAIVLLTFMCTNVCYIERVGFSIAYTVAADAVGTNQANKGMILSMFYYGYVLSQIPGGWAAQRLGGRLVLLLSFVLWSSICAVVPLDPNRVILLVLSRLLVGVAQGLIFPSIHTVLAQWVPPQERSRSVSLTTSGMYLGAACGMLLLPSLVKNMGPQSVFSVEAMLGVAWLLIWFKFASDPPRTDLPKVASKDKMKVQTGGIMAPRTVKIPWARILFSLPIWAIVVNNFTFHYALYVLMNWLPTYFKLGLQLSLQDMGFSKMLPYLNMFLFSNIGGVLADHLITRKILSVTKTRKLLNTVGFVVSAIALMALPLFRTPSGAIFCSSVSLGFLALGRAGFAVNHMDVAPKFAGIVMGISNTAGTLAGIVGVGLTGRILEAAKASNMDLTSSESWRTVFFVPGYLCIFSSFIFLIFSTGEKIFE
What is the function of this protein?
Probable anion transporter.
What are the official names of this protein?
Probable anion transporter 6, Phosphate transporter 4;6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRC_SALTY
Sequence: MNTFFRLTALAGLLALAGQSFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDEAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTVLGDELRTGKLDVFYDLYNLAQKRRFERYQYALKVLERPMDFTGNDTFNLDRSKAPWPKDEAELNALWDGKVKFDELSLKLTGKSDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKSISVGDRIVGVGQAGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRIITLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVNSIVIDLRSNGGGALTEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYGRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAAKYVKSDDLAPFGPELLKEHNARIAKDPEFQYIMKDIARFNAMKDKRNIVSLNYAQREKENNEEDALRLARINDRFKREGKPLLKKLDDLPKDYQEPDPYLDETVKIALDLAHLEKEKPAEQAAANK
What is the function of this protein?
Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3).  May be involved in protection of the bacterium from thermal and osmotic stresses (By similarity).
What are the official names of this protein?
Tail-specific protease, C-terminal-processing peptidase, PRC protein, Protease Re.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Periplasmic side.
Protein: Y1572_CAMFF
Sequence: MNNERLDNISNSLGISKRKRTLFELEQISDNEMKLIIKNGKLNLSVPWFGMSGNTPCTLVPAGLFEAIINTLKNAQKENFELKLEKSIWQHIPVDFGDVWSVAIDEIKKSKFKKEPNLDRVVKKIKKEHPNLFVDMQSLIQSKEN
What are the official names of this protein?
UPF0763 protein CFF8240_1572.
What is the protein family that this protein belongs to?
Belongs to the UPF0763 family.
Protein: TM16B_ARATH
Sequence: MAGRLLANLIVMGSGIIGRAVFQAYRQALANASKSGVAQEAMQNGVRQAGKAITEQEARQILGVTEKTSWEEILQKYDKLFENNAKAGSFYLQSKVHRAKECLEVVYRSQGNGTPS
What is the function of this protein?
Regulates ATP-dependent protein translocation into the mitochondrial matrix (By similarity).  Involved in the uptake of thaxtomin, a phytotoxin produced by Streptomyces bacteria, that causes dramatic cell swelling, reduced seedling growth, and inhibition of cellulose synthesis (PubMed:12897252, PubMed:23638731).  Modulates polar auxin transport (PubMed:23638731).  Involved in importing a negative regulator of plant immunity into mitochondria, thus protecting plants from over-accumulation of reactive oxygen species (ROS) and preventing autoimmunity.  Confers sensitivity to virulent pathogens such as the oomycete H. arabidopsidis Noco2 and the bacteria P. syringae pv.  maculicola ES4326 (PubMed:24153405).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit PAM16 like 2, AtPAM16, AtPAM16L2, Presequence translocated-associated motor subunit PAM16, Protein MUTANT SNC1-ENHANCING 5, Protein THAXTOMIN A RESISTANT 1.
What is the protein family that this protein belongs to?
Belongs to the TIM16/PAM16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Cytoplasm.
Protein: HEXPP_SACS2
Sequence: MSIIEFWLEAKATIDRLIEQFLNSNRDWDLVDISSYILKDGKRFRGTLNMFFTVALGGDIKDSYGGALAIEILHSASLALDDIVDLDATRRGDKAAWVVYGNRKVIFITNYLIPTALRIIQTSYGDDALNTSIELWKDTSVGALRDMYDNSDYIRTIELKTGSLFKLSTVLSAYASKHYNTKQQMLDVGKYLGIIYQVIDDFVDYKTKKVEEIDGSAKQLFKYYREGKLEEYVRSVYLEYKQKYDELISNIPFQSKYLSEIRSLPEFLANGLLKEANIDKI
What is the function of this protein?
Catalyzes consecutive E-type condensation of two isopentenyl pyrophosphate (IPP) molecules with an allylic substrate such as geranylgeranyl diphosphate (GGPP), farnesyl diphosphate (FPP) or geranyl diphosphate (GPP) to yield the medium-chain product trans-C30-hexaprenyl pyrophosphate (HexPP).  GGPP is the physiological substrate.
What are the official names of this protein?
Hexaprenyl pyrophosphate synthase, HexPP, Medium-chain HexPP.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: PYRD_SCHPO
Sequence: MYQRSLFRGVAQGLKRSSVRFQSTSSGSSNGNFFLRHWKLLSVIGSFTAGVAIYDMSDVRSFIHGRIEMPLFHAFTTPEFSHRVAILAASWGITPKDRVADDPSLAVEVWGKKFCNPIGLAAGFDKQADAISGLLNFGFSYLEIGSVTPKPQPGNPKPRYFRLKPDLSVINRYGFNSIGHDAILAKIQKRVRKYIAKTSPQLLKQFDANPASCTDPAVLGVPRSLIPNKFLGINLGKNKNGNEIEDYVEGVRTFGNFADILVINVSSPNTPGLRNLQKKSALSTLLTAVVSERNKLNSPHPPVLVKIAPDLNEEELTDIADVLKKCKIDGVIVGNTTVQRPKTLKSTSHVEETGGLSGPPLKPIALNTLRTLRKHLSSDIPIIGCGGISSGKDAIEYARAGATMVQVYTALGYDGPVIAHKIKQEILAELKGKRWVDIIGKEE
What is the function of this protein?
In the de novo pyrimidine biosynthesis pathway, catalyzes the stereospecific oxidation of (S)-dihydroorotate to orotate with reduction of flavin and the transfer of electrons to ubiquinone, which is part of the repiratory chain.  Does not use fumarate and NAD as electron acceptors.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOD, DHODase, DHOdehase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RS15_LACH4
Sequence: MAISKTEKDNIIKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRELIKKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ACYP_RHOPS
Sequence: MSTTIRQVMVRGRVQGVGYRAWLAMTAEAQGLEGWVRNRRDGSVEALLAGRETVVAEMISRCRTGPSAAHVDEVIVEEAGQDALNLRYAGERFSILSTL
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RESA_ALKCK
Sequence: MGKSKKKRSIIRFTVLFAIVCAIGYTIYANAASEQGAVKVGEPATNFALVDLEQERFELGQNQGKGVFINFWGTFCEPCEREMPYIENAYEQYKDEVEMIAVNVDEAPLTVQSFINRHGLTFPVAIDERREVTRAYGIGPLPATILVDEHGIVQKVHTGAMTEEMVHEFFQSIVPDA
What is the function of this protein?
Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis.  May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached (By similarity).
What are the official names of this protein?
Probable thiol-disulfide oxidoreductase ResA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. ResA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane.
Protein: ASF1_CAEEL
Sequence: MASRVNIVQVQILDNPAMFVDKFKLEITFEVFEHLPHDLEWELVYVGSGTSRDFDQVLDSALVGPIPEGRHKFVFDADHPDISKIPVDDIVGVSVLLLRCKYNDQEFINMGWFVANEYTEEELKENPPSQPLIEKLSRKVETEDLRITTFPIRWTDEDPVAEPVEDEANRVFAEDDLMPLNDDGQEDDDEEEEDDDEMEANAEEVDLNESFNERLANALDGAEQKGADEKMEDDGANEDVDMADDEPGVQINTDTKVPESMAEPLSDKTNNEMVQ
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Probable histone chaperone asf-1, Anti-silencing function protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPB48_MYCTO
Sequence: MRTTIDLDDDILRALKRRQREERKTLGQLASELLAQALAAEPPPNVDIRWSTADLRPRVDLDDKDAVWAILDRG
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC48 (Potential).
What are the official names of this protein?
Putative antitoxin VapB48.
Protein: AC4CH_ECOSE
Sequence: MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRFEDDGYFCTIEVTATSTITLETLTEKHAEQENMTLTELIKVIADIYPGQTQFYVIEFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: DEOB_STRPQ
Sequence: MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISEAAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGDPGNFTRTANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADHGNDPTYAGTDHTREYIPLLAYSVSFTGNGLIPQGHFADISATVAENFGVDTAMIGESFLSHLK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15A_DANRE
Sequence: MVRMNVLADALKSINNAEKRGKRQVLLRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF
What is the function of this protein?
Component of the small ribosomal subunit (By similarity).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  Required for erythropoiesis during embryonic development (PubMed:27909223).
What are the official names of this protein?
40S ribosomal protein S15a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS19_KLEP3
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YR203_MIMIV
Sequence: MDSHIHNDTDDWFNDLDQKSIQVISNKLIPEESNSSDEEISLENINSRSNFIDDNDKIEHIFIEDILKKDVVNLSSNELLQYQCSVAYFIQVLFEGLNDSNELIANKSNFNIKTTSDKMNSMVEYLEWISGVSEILAKRIGQQIYQFIPDRNNTITRSSYNFCPASTQCKKFYSKNENPTCKSHHFVHSLLKYDVDSVIYYLKHNNKNGSFNTDELNNLHLSIKTICFVTRHMAREISYIENITKNNSEQFHRNNPADLTKKKSTNVSGKKSWDSVSTIRTHKATKTFPQNKTRQCSNTKTTTKSTMTPINNGFKESPNQILKIKNGVNRYSILSEY
What are the official names of this protein?
Uncharacterized protein R203.
Protein: Y1344_LISIN
Sequence: MWIYILVGIICLLAGLAGGFFIARRYMMSYLKNNPPINEQMLQMMMAQMGQKPSQKKINQMMSAMNKQQEKEKPKKAKK
What are the official names of this protein?
UPF0154 protein lin1344.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VIRB9_BRUA2
Sequence: MKRFLLACILITLASPSWATKIPSGSKYDSRIQYVDYNSGDVVLVRALPGVGARIVFAPGENIEDVASGFTQGWEFKASHNILYLKARSMTLSHSNQSIDMAPEPGKWDTNLMVTTDQRMYDFDLRLMPGRNNQRVAYRVQFRYPAAAAAAAVAAAQKRVVQARMNARPSPVNWNYTMQVGTNSASIAPTLAYDDGRFTYLRFPNNRDFPAAFLVAEDKSESIVNSHIDPSAPDILVLHRVAKQMVLRLGNKVIGIYNESFNPDGVPARDGTTVPGVKRVIKSPGENLQ
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.
What are the official names of this protein?
Type IV secretion system protein virB9.
What is the protein family that this protein belongs to?
Belongs to the TrbG/VirB9 family.
Protein: RL31B_SALTY
Sequence: MKPDIHPVYRTVVFHDTSANEYVKVGSTIKTEREIELDGVTYPYVTIDVSSKSHPFYTGRQKTFDSESSAARFQKRFGHFIGAKRG
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RL7_MYCS5
Sequence: MAKLTKETFVESLKEMSIKEVMELVEAMKEEFGVDPAAAVAVAAAPGEAAEAAKTSVKVVLKADNGKKVQIIKAVKDLLGGSLMDAKKIVDNLPAVVKENIKPEEAEPIRAALVEAGAEVSVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: NSF1C_RAT
Sequence: MAEERQDALREFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDNRVTSFRDLIHDQDEEEEEEEGQRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGERRRHSGQDVHVVLKLWKTGFSLDNGDLRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLNTSSPAQQAENEAKASSSILINEAEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFVLMTTFPNKELADENQTLKEANLLNAVIVQRLT
What is the function of this protein?
Reduces the ATPase activity of VCP (PubMed:9824302, PubMed:9214505).  Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis (PubMed:12411482).  May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (PubMed:10930451).  Inhibits the activity of CTSL (in vitro) (By similarity).  Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (By similarity).  Also, regulates spindle orientation during mitosis (By similarity).
What are the official names of this protein?
NSFL1 cofactor p47, XY body-associated protein XY40, p97 cofactor p47.
What is the protein family that this protein belongs to?
Belongs to the NSFL1C family.
What are the subcellular locations of this protein?
Nucleus. Golgi apparatus, Golgi stack. Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Predominantly nuclear in interphase cells (PubMed:12810701). Bound to the axial elements of sex chromosomes in pachytene spermatocytes (PubMed:1495983). A small proportion of the protein is cytoplasmic, associated with Golgi stacks (PubMed:12810701). Localizes to centrosome during mitotic prophase and metaphase (PubMed:23649807).
Protein: IC1_RABIT
Sequence: VARSLLIFEVQQPFLFLL
What is the function of this protein?
Activation of the C1 complex is under control of the C1-inhibitor.  It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases.  May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins.  Very efficient inhibitor of FXIIa.  Inhibits chymotrypsin and kallikrein.
What are the official names of this protein?
Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LRC56_HUMAN
Sequence: MDLGWDRSRGPRRSTSSVRVRELSWQGLHNPCPQSKGPGSQRDRLGEQLVEEYLSPARLQALARVDDLRLVRTLEMCVDTREGSLGNFGVHLPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRAEVRKLIPQLQVLDEVPAAHTGPPAPPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLPETQSRASRPWPFSLLVRGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPEQLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCPGPKPAPDAAARPPRAAELSHPSPVPT
What is the function of this protein?
Required for the assembly of dynein arms.
What are the official names of this protein?
Leucine-rich repeat-containing protein 56.
What is the protein family that this protein belongs to?
Belongs to the LRRC56 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: COAD_MYCUA
Sequence: MTGAVCPGSFDPVTLGHVDVFERAAAQFDEVVVAILVNPAKKGMFDLDERIAMIEESTAHLPNLRVEAGQGLVVDFVKAQGMNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNRRLRERTK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_BURMA
Sequence: MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAARQMSLRLGRNSACFVHLTLVPFIATAGELKTKPTQHSVQKLREIGISPHVLLCRADRPIPDDESKKISLFSNVPEDAVISVWDVDSIYKIPQMLHDQGLDRLICEELRLDPQPADLRMWAALVEKLQNPKHEVTIGMVGKYVDLTESYKSLIEALRHASIHTSTKVNIEYIDSEELETNGTASLAHLDAVLVPGGFGRRGTEGKIAAVRYAREAKVPYLGICLGMQLAVIEFARDVVGLKQANSTEFDPNTPERVVALITEWYDREGKVEKRTEDSDLGGTMRLGSQRCPIKPGTLAEAIYGKDVNERHRHRYEVNNRFVPQLEAGGLVISARTPSEDLPEMMELPSTMHPWFVGVQFHPEFTSTPRDGHPLFKSFVQAALACQQTRAGAKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DNAA_STRP2
Sequence: MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFLPRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYSPKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLGKTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLIDDIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQTITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVKKIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVLARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKKKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication (PubMed:34373624).  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.