PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_PROM2
Sequence: MQDHQATNESFDIIVIGGGHAGCEAAITTAKLGFSTALFTINLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADETAIQKRILNASRGPAVWALRAQTDKREYSKRMIEILQNTDNLSLKEAMITELDIAKSEQVGLNSKKVVKKRIKGVKTFFGSYYSAKSVIITAGTFLEGKIWIGNKSMSAGRSGEQAAQGLTQNLHEIGIKTERLKTGTPARVDKKSIIFDELDTQPSTAAGKYFSFDPDIKNNMPQVSCHITRTTSKTHQLIRDNLHLTPIYGGFIDSKGPRYCPSIEDKIVKFADKKSHQIFLEPEGINTPEIYVQGFSTGLPENIQLELLRTLPGLSKCKMLRPAYAVEYEYIPATQLQTSLETKEIEYLFSAGQINGTTGYEEAAAQGLVAGVNATRKLNKKDPIIFTRESSYIGTMINDLITKDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGYQIGLIDEKRWSAYEEKMKLLEEEKLRLNNTRLKNTDEISKKIELDTGSKIKGSTTLKELLKRPNFHYLDLIKYNLAKKNLGYSIQEGVEIDIKYEGYLKRQKNNIEQINRQSCKSLPQEINYEKIDTLSLEARENLNKIKPKNFGDASKIPGVSKADLTALLVWLKIREINKEKTNIFCQKKLSS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTHP_TREPA
Sequence: MVVKTVRVLNRAGVHARPAALIVQAASRFDSKIMLVRDTIRVNAKSIMGVMAMAAGCGSELELVVEGPDEVAALSAIERLFQNKFEEE
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I.  Phospho-HPr then transfers it to the PTS EIIA domain.
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR4_CANGA
Sequence: MNDISMMGYPGMGQQQPQPQQAQQPQQQPISMQPHTMMNMMNTNLPPPGMMMGGAGSNTGNENMINHGLMSGNPVSGIPNNNSHQLLDQLINKNPNNMGIPQQQQDSLAAQMQLPMGGMPMGNGSAHNGNVGMNNNNTGGNNNIPMGNANVLRNNNIIGNLGGSSLAGGNMNSGMPGISTFGNTPGQLAAPPIQPNANANNPMYHPHLEDPSLMNNPIWKLQLQLATVSAQSVGQPNIYARQNAMKKYLATQVPPQNQTQQQAQAQSQIAETSKSLVDCTKQALMDIMAPDDSKLKGMSAPNTASTTTNSTISTPTTSKIDMNNSREQPSTPSLLLQHKKLSQYSIDEDDEVENRMVAPKDTKYNDQIWHAIDLSNLQIFNISPNLMKYDFLTRLYLNGNGLESIPSSIRNLKNLRVLDLSHNKLKELPKEIGNCYQLKYLYFFDNQITTLPWELGNLCNIQFLGCEGNPLDKELLKILTEKSFTGLIFYLRDNRPEVPYPHDRKFIEINADGEPEKEYDTVQEAERNLSSDMQKKSFTMLSYNTLCQHYATPKMYRYTPSWALSWDYRREKLKEQILNFNTDIICLQEVEAKTFEDFWQPLLEKHGYTGLFHAKTRAKTMQSKDSKKVDGCCAFYKTSKFKMLFKECVDFSGLWMKHKKFQRTEDYLNRAMNKDNVAIVMKLQHIQSGEIMWLVTTHLHWDPKFNDVKTFQVGVLLDHMETLLKEQNPKQDVKKYPLVICGDLNSYLSSSVYELFSTGRVQHHHDGKDRDFGYFSEDNFSHNLALKSSYNCIGELAFTNFTPSFTDVIDYIWFSSQALRVRGLLGEVDSEYVSNFIGFPNDKFPSDHIPLLGRYEFLKSNNTQNSNSGSRKV
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity).  Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
What are the official names of this protein?
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4, Carbon catabolite repressor protein 4, Cytoplasmic deadenylase, Glucose-repressible alcohol dehydrogenase transcriptional effector.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NODJ_HYPPI
Sequence: MELIVIIITLAFCILLYGTRWRAALDPREPRLISPTVPLIGHILGIATDGFGYFSKLNDKYGLPAFSLQMPLSRLYVITSSELVPAIQRQSQNIRFDTFEFTLAAERVGGVSGPGLKLLKGSIVDELQHAMHHALIGHGLDAMNLSMIEAIKPSIDELQSQKQAAFDLFAWCKRSITMASTDSVYGPMNPFRSIEVERAFWDFASNMNMIILNVLPFLTARKSLDDRRKVVDALTEYYNLGGHENSSEMTYGRWEVQYNKGITTQDIARMEIVNAIGVLSNTAPSTFWTLFEIYSRPSLLRDLRQELVASAVYTHPGTDGGIVRTIDLSAVRAKCSLLLGTFQEVLRMRSNAIVTRMVHEDTILNERVLFKKGSVIVIPARCVNREKSVWGETGDSFDAYRYLGQGKSGTSRSGRNVTRVAFQSFGTAPNICPGRHFASGEILAVVAMVILRFDMEPVLGEWIPPKANVKTLASSIQTPAGEFMVTLRERKEFKDDKWDFRVTEGDSKFPLLVG
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes nodulisporic acids (NA).  Nodulisporic acid A (NAA) and its chemically modified derivatives are of particular significance because of their highly potent insecticidal activity against blood-feeding arthropods and lack of observable adverse effects on mammals, in particular the tremogenicity associated with the paspaline-derived IDTs is not observed (PubMed:29283570).  The geranylgeranyl diphosphate (GGPP) synthase ggs1, localized outside of the cluster, is proposed to catalyze the first step in nodulisporic acid biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:29283570).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase nodC then forms 3-geranylgeranylindole (3-GGI) (PubMed:29283570).  Epoxidation by the FAD-dependent monooxygenase nodM leads to a single-epoxidized-GGI that is substrate of the terpene cyclase nodB for cyclization to yield emindole SB (PubMed:29283570).  The terminal methyl carbon, C28, of emindole SB is then oxidized by the cytochrome P450 monooxygenase nodW to produce nodulisporic acid F (NAF), the pentacyclic core of NAA (PubMed:29283570).  NAF is converted to nodulisporic acid E (NAE) via prenylation.  This step is probably performed by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  Several oxidation steps performed by the FAD-linked oxidoreductase nodO and one of the cytochrome P450 monooxygenase nodR, nodX or nodZ further convert NAE to nodulisporic acid D (NAD) (Probable).  NAD is substrate of cytochrome P450 monooxygenase nodJ to produce the precursor of nodulisporic acid C (NAC), converted to NAC by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  The FAD-dependent monooxygenase nodY2 then oxidizes NAC to nodulisporic acid B (NAB) (Probable).  Finally NAB is converted to NAA by one of the cytochrome P450 monooxygenases nodR, nodX or nodZ (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase nodJ, Nodulisporic acid biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATPB_PARMW
Sequence: MVASAPASAGTKGVIRQVIGPVLDVEFPAGKLPKIYNALRVETKNTAGQDVALTAEVQQLLGDHRVRAVAMSGTDGLVRGMEIADTGAPISVPVGEATLGRIFNVLGEPVDEQGPVNASATAPIHRDAPNLTELETKPKVFETGIKVIDLLAPYRQGGKVGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYEEFKESGVINADDLSKSKVALCYGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFVDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGALQERVASTVEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLNRALASKGIYPAVDPLDSTSTMLQPAVVGDEHYRTARLVQSTLQRYKELQDIIAILGLDELSEDDRQTVDRARKVEKFLSQPFFVAEIFTGMPGKYVKLEETIAGFNQILAGELDHLPEAAFYLVGSIEEAKAKAEKIAAETK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: POPA_GALM3
Sequence: MARTPWLPNAYPPARRSDHVDIYKSALRGDVRVQDPYQWLEEYTDETDKWTTAQEVFTRTYLDKNPDLPRLEKAFQACNDYPKSYAPYLHDDNRWYWYYNSGLEPQTALYRSKDSSLPDLSTADGSGGDLFFDPNALSNDGTAALSTYAFSDCGKYFAYGISFSGSDFVTIYVRLTDSPLTKDVDAKNDKGRLPEEIKFVKFSSIGWTPDSKGFFYQRYPDTSTVTQENGPIATEGDLDAMVYYHRLGTPQSEDTLIYQDKEHRDWMFSIDVTDDGNYLLLYILKDSSRQNLLWIAAFDPANLGPNIKWQKVFDEYHSEYEIITNKGSLFYVRTNESAPQYRVITVDIAKGNEINELIPETDAYLSSITSVNKGYFALVYKRNVKDEVYVYSHAGNQLARLAEDFVGAAHVSGREKHSSFFVELNGFTSPGTIGRYKFTDPEEQRWSIYRTTKLNGLNTEDFEASQVWYESKDGTSIPMFIVRHKSTKFDGTAPVIQYGYGGFSISIDPFFSATILTFLQKYGVVFALPNIRGGGEFGEDWHLAGCREKKGNCFDDFIAATQYLVKNKYAAPDKVTINGGSNGGLLVSACVNRAPEGTFGCAVADVGVHDLLKFHKFTIGKAWTSDYGNPDDPNDFDFIFPISPLQNIPKDKVFPPMLLLTADHDDRVVPMHSFKLAAELQYSLPHNPNPLLIRIDKKAGHGAGKSTQQKIKESADKWGFVAQSLGLVWKDSTEQPNL
What is the function of this protein?
Housekeeping prolyl oligopeptidase (POP) that behaves like a conventional POP by cleaving peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long (PubMed:22202811).
What are the official names of this protein?
Prolyl oligopeptidase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
Protein: SYH_HELAH
Sequence: MITPKVLSGFKDRLPKDAIQKAQLLSKVSVVFQSFGFVPIETPHLEYAETLLPDASSDIQKEIYRFKDHGGRDVALRFDLTVPLARFVSLYHQTLGMPFKRYAIGNVFRGERAQKGRYREFTQCDFDFIGSESLVCDAEIIQVVIASLKALDLEDFCVSINHRKILNGICEYFGISQVTGVLRIVDKLEKIGLNGVEEELKKECDLNPNTIKGLLEMVQIKQDDLSHAEFFEKIAYLKDCNENLKKGIQDLEKLYQLLGDLQISQNLYKIDFSIARGLGYYTGIVYETTLNDMKSLGSVCSGGRYDHLTKNFSKEDLQGVGASIGIDRLIVALSGMQLLDERSTQAKVLIACMNEEYFSYANRLAESLRQSGIFSEVYPEAQKIKKPFSYANHKGHEFVAIIGEEEFKSETLSLKNMHSGMQLNCLSFLKALEIIGENDEDL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCS1A_DICDI
Sequence: MNHLKDQSKSIVLGISSGIGIFLISGGINIFKNVGQYILNRINSNIYYRIDVDSKDKSFEWLLYWLSENDSIKVSNHLNAETVYNLVGKNPKVILVPSVGKHRIVYKGKWIWIDRVRDQQFDMGAGAPFESISISTYKSNAQLINQLLQEAMTLSLNRDIGKTVIYINGGNGNWERFGNPRSIRSLSSVILADDLKSKLIEDIKSFITNESWYRNRGIPYRRGYLLYGEPGNGKSSLINAIAGELNLDICIVSLSSKDIDDKQINHLLNNAPPKSILLIEDIDAAFKSHRDNVDSNNNNSNNNNSLTYSGLLNALDGVASQEGRILFMTTNKIELLDSALIREGRIDLKIKVSNATKSQAAQLFTHFYNLPTDNQLAIRFSENLHDHQLSMSQIQGFLLKYINSPEKAIEEVQSITPFNLN
What is the function of this protein?
Chaperone necessary for the assembly of mitochondrial respiratory chain complex III.
What are the official names of this protein?
Probable mitochondrial chaperone BCS1-A, BCS1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: HBB_CROCR
Sequence: GFLTAEEKSLVNDLWSKVNVDEVGGEALGRLLVVYPWTQRFFQSFGDLSSADAIMGNSKVKAHGKKVLNSFSDGLKHIDDLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGNEFTPPVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CP126_MYCBO
Sequence: MTTAAGLSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVEPGFDFRGSRRATMPRLNVEDAGSRLYTYALELIAGKRAEPADDMLSVVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELRGG
What are the official names of this protein?
Putative cytochrome P450 126.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: AROA_HYPNA
Sequence: MVWTSHPVKRLAGAIRAPGDKSCSHRALIFGGLAEGESRFSGLLEGDDVLRTGQAMEAMGATVTRTGPGSWDVTGVGAKGLSSPKGVLDFGNSGTGSRLLMGVMAGYDLTASLTGDASLCSRPMNRVLNPLRQMGLKDTAGPDGKLPFTLTGSKSLKAIRYAPPQASAQVKSAVLLAGLNAEGETVVAEAKATRDHTERMLQGFGATLSFRMAPGGVHEIALKGGQRLRGLDAEIPGDPSSAAFLIAAGLLSPQGDVLVEGVMSNPTRSGFYDVADLMGASLGADERGEAAGERLIDIHSGYAGLKGIHVPERLVASMIDEFPILAVLAAFATGETRVTGAEELRVKESDRIGAVVAMLRVNGVEVEETEDGFTVQGCGGRVPGGGLVETRHDHRIAMSALVMGTAAQKPVSVDDISMIDTSYPEFMSHMATLGADIRS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH602_PARXL
Sequence: MSAKDVKFHDSARSRIVKGVNVLADAVKVTLGPKGRNVLIERSFGAPTITKDGVSVAKEIELKDRFENMGAQVVKQVASKTADVAGDGTTTATVLAQSIVQEGMKHVAAGMNPMDLKRGIDKAVAAVLDELHRLSKPIKTSREIAQVGAISANADEAIGKIIADAMDKVGKEGVITVEDGKSLENELEVVEGMQFDRGYLSPYFINDPDKQVAHLDDPLILLHDKKISSIRDLLPVLEAAAKAGKPLLIIAEDVEGEALTTLVVNSMRGVLKVAAVKAPGFGDRRKALLEDIAILTGATVISEETGKQLEKATLEELGRAKRVEVQKENTIIIDGAGDQTRIDARVKAIRAQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKDRVDDALHATRAAVEEGIVPGGGVALLRARSAISSLTGANADQDAGIRIVLRALEAPLRVIAANAGDEPSVVVAKVLSGKGNYGYNAATGEYGDLVETGVVDPTKVTRTALQNAASIAGLILTTDATVAEAPKEEKAVPAPAPELEY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2/3, 60 kDa chaperonin 2/3, Chaperonin-60 2/3, Cpn60 2/3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_YERPG
Sequence: MAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAPVATPHELADYDGIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTPYGATTIAGGDGSRQPSAEELAIARFQGEHVAKITAKLKG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: PUR5_ACIBS
Sequence: MSNSTSTPNTGLSYKDAGVDIEAGDALVDRIKSVAKRTTRPEVMGGLGGFGALCKIPKGYEEPVLVSGTDGVGTKLRLALNLNRHDTIGQDLVAMCVNDLLVCGAEPLFFLDYYATGHLNVDVAANVVTGIGKGCELAGCALVGGETAEMPGMYEGEDYDLAGFAVGVVEQSKIIDGSKVKSGDVLIGVASSGAHSNGYSLLRKILDVKNVDLTQVIDGRPLADVAMEPTRIYVKPVLELCKQVDVHAMAHITGGGLPGNLPRVLPNGAQAVINEASWEWPELFKLLQREGNVERFEMYRTFNCGVGMVIAVDANDAEKAIEVLNAQGEKAWKIGHIQENAESVEGADEKIRVIFE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_ACISJ
Sequence: MSTPDVVREAQSTEAYNPLAKQKAAAKLSRIPIKVEQGEVLKKPEWIRVKAGSPTTRFYEIKNILREHKLHTVCEEASCPNIGECFGRGTATFMIMGDKCTRRCPFCDVGHGRPDPLDKDEPLNLAKTIAALRLKYVVITSVDRDDLRDGGSGHFVECIQRTRELSPSTQIEILTPDFRGRDDRALEILKAAPPDVMNHNLETVPRLYKEARPGSDYQFSLNLLKKFKQLHPGVPTKSGLMVGLGETDEEILEVMRDMRAHGIEMLTIGQYLAPSNSHLPVRRYVHPDTFKMFEEEAYKMGFSHAAVGAMVRSSYHADQQAHAAGV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNG1_PONAB
Sequence: MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNNINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKLSKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRIAHLPTIPEMVP
What is the function of this protein?
May play a role in growth regulation.  Is associated with G2/M phase arrest in response to DNA damage.  May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
What are the official names of this protein?
Cyclin-G1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin G subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=DNA replication foci after DNA damage.
Protein: PIP_LEPBY
Sequence: MRQLYPAIAPYQSGMLPVSALHTIYYEQSGNPNGKPVVFLHGGPGGGTIPTYRQYFDPSKWRIILFDQRGAGKSTPHAELRENTTWDLVSDIEKLRSHLNIDRWFVFGGSWGSTLSLAYSQTHPDRCLGLILRGIFLLRRKEILWFYQDGASWIFPDAWEHYLEPIPPEERDDMISAYYRRLTSKDAEIRSTAAKAWSVWEGTTSRLIVDPSLQSKFADDEFADAFARIECHYFINRGFFETDDQLLQNCDRIAHIPTVIVQGRYDVVCPMTSAWALHKALPESELIVVPDAGHSMMEAGILSALIDATDRFVAQKTNGKI
What is the function of this protein?
Specifically catalyzes the removal of N-terminal proline residues from peptides.
What are the official names of this protein?
Probable proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBG1_PLEMO
Sequence: MSNFTAEDKAAITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGSLSSPSAIMGNPKVKAHGVKVLTSLGEAIKNLDDLKGTFDQLSELHCDKLHVDPENFRLLGNVLVTVLAILHGKEFTPEVQASRQKMVAGVASALGSRYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma-1, Gamma-1-globin, Hemoglobin gamma-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PLSX_STAAW
Sequence: MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: KAX54_HOTTA
Sequence: AFCNLRRCELSCRSLGLLGKCIGEECKCVPY
What is the function of this protein?
Blocks small conductance calcium-activated potassium channels (PubMed:12239213).  Shows activity on KCa2. 2/KCNN2 (IC(50)=0. 0243 nM), KCa2. 3/KCNN3 (IC(50)=1. 7 nM), and KCa2. 1/KCNN1 (IC(50)=42 nM) (PubMed:12239213).  Induces cell death when tested on human T lymphoblastic leukemia Jurkat E6. 1 and human breast cancer MDA-MB-231 cell lines which constituvely express KCa2. 2/KCNN2, but not on human peripheral blood lymphocytes (which do not express KCa2. 2/KCNN2) (PubMed:24821061).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 5.4, Tamapin.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 05 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4007_STRCO
Sequence: MPSSPSSTTPAPTSTPAARREPSGKGPSGAAARLFLPLIALCTAVTAANIYLAAPLLPLIAHDMGSTPSAVAWLASVAQLGYAAGLLFFAPLGDSVNRRRLVAALSLVATAALLTAAASAGTGALAGAVLVASAATVVPQLLVPLVAERAPADRRARHVAAVIAGLFTGVVAARVLGGLAGQAFGWRAVFVGAAVLTAVLGLATAYILPVERRQRRGPLFAGLVAIPGLVRRSPDLWRACVRQAGMYGAWSALWTSLALLLTEGEGYGMTTAAAGLFGLFGLAASVVAPLAGGLVDRFGAAKVVRSAYALAALSVPLFWLGGQVMAALCAAAVLVHAALVASHVANQTLALTTTSAPATANTAYVVAGFAGGALASALAGPAFGHWGWGGVCAVAGAWLVLGWTATAVRPARSARSARSARSVRSVRSAR
What are the official names of this protein?
Probable transporter SCO4007.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RK20_CUCSA
Sequence: MTRIKRGYIARRRRTKIRLFASSFRGAHSRLTRTITQQKIRALASAYRDRGRQKRNFRQLWIARINAVIRSNNVDYSYSRFIHNLYKRQLLLNRKILAQIAILNRNCLYMISNEIIK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: POLG_CYVV
Sequence: IKKEGLWIPKLEPERVVSILEWDRAAEPEHRLEAICASMIEAWGYDDLLNHIRRFYLWVLDQAPYKQLSAEGKAPYISEVALKSLYTGKPATSCELEVYNKIHQEQHDEFDDSQMKFVFQSDKEKLNVGEQQKSKDKESRQRDQEGENSNRQIIPDRDINAGTTGTFSVPKLKKISGKLSLPKIKGKGLLNLDHLLVYVPNQDDISNNIATQEQLEAWHEGVKNAYEVDDQQMEIICNGLMVWCIENGTSGDLQGEWTMMDGEKQVTFPLKPILDFAKPTLRQIMAHFSQAAESYIEFRNSTEKYMPRYGLQRNLTDYGLARYAFDFYRLTSKTPARAREAHMQMKAAAIRGKSNHMFGLDGNVGTDEENTERHTANDVNRNMHHIAGARF
What is the function of this protein?
Involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae genome polyprotein family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion.
Protein: EIF3D_XENLA
Sequence: MAKFQAPVINDNALGWGPCAIPDQFKDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHDEDETSFQLVDTTKMQKTAYQRNRMRFAQRNLRRDKDRRNMLQFNMQTLPKSAKQKERDRLRLQKKFQKQFGVRQKWDQRSQAQLKPRDSSVEVRSDWEVKEEMDFPRLMKMRYMEVADPTDIECCGAVEYYDKAFDRITTRNERPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMCCTRSVNSWDIVVQRVGSKIFFDKRDNSDFDLLTVSETANEPPQDEVNSLNSPRNLAMEATYINHNFSQQCLRMGKEKHTFPNPNPFIEDDVDKNEVASVAYRYRRWKLGDDIDLVVRCEHDGVMTGANGEVSFINIKTLNEWDSKYCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYNVKDSTRHVVLGTQQFKPNEFANQINLSMENAWGILRCVVDICMKLDEGKYLILKDPNKQVIRIYSLPDGTFSSDEEEDDDDEDEEVEEEES
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d, Eukaryotic translation initiation factor 3 subunit 7.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.