PharMolix/UniProtQA huggingface dataset:
Protein: AP2A_SHEEP
Sequence: MPPRLASVKIPYDWGRKGPFRFWRIFCQSRAVGWFLAAACGRAGRFRTQPAEWPTPDAVFSPLGLALFQDRHDGASNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHGLGSGLGDLPIHSLPHAIEDVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSSIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNSAKSSDKEEKHRK
What is the function of this protein?
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.  AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development.  They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.  AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.  Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation.  Associates with chromatin to the PITX2 P1 promoter region (By similarity).
What are the official names of this protein?
Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2.
What is the protein family that this protein belongs to?
Belongs to the AP-2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SODM1_MAIZE
Sequence: MALRTLASKKVLSFPFGGAGRPLAAAASARGVTTVTLPDLSYDFGALEPAISGEIMRLHHQKHHATYVANYNKALEQLETAVSKGDASAVVQLQAAIKFNGGGHVNHSIFWKNLKPISEGGGEPPHGKLGWAIDEDFGSFEALVKKMNAEGAALQGSGWVWLALDKEAKKVSVETTANQDPLVTKGASLVPLLGIDVWEHAYYLQYKNVRPDYLNNIWKVMNWKYAGEVYENVLA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 3.1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ADDB_BACCN
Sequence: MSLRFVIGRAGSGKSTLCLREVQEELKERPRGKTILYLVPEQMTFQTQQALIGSEEVRASIRAQVFSFSRLAWKVLQEVGGASRLHIDEAGVHMLLRKIIESRKEGLYVFQKAAEQNGFFEHLGGMIAEFKRYNITPSHVYEMWQQLDAHSSSAEQKLLANKIYDLQLLYDDFERALIGKYLDSEDYLQLLIEKLPFSEYVKDAEIYIDGFHSFSPQELEIIRQLMRCGARMTITLTVDEKTFAQPVNELDLFYETVLTYEKVKQVAREEKVVMEKTISLVEQPRFHSPALAHLEAHYESRPNEKFYGETSIAIHTAANLRAEVEGVAREIRRLVAEENYRYRDIAVLLRNGESYYDVLRTLFADYDIPHFIDEKRSMSHHPLVECIRSALEIISGNWRYDAVFRCVKTELLYPLDVKKEVMREEMDEFENYCLAYGVQGKKWTADEPWTYRRYRSLDEGNEVITDRERQMEEKMNRLREIVRTPIIRLQKRLKRASTVMQMCEAVYLFLEELDVPKKLEQLRVRAEESGDFLFATDHDQVWEEVMNLLDTFVEMLGEESMSLSVFIDVMTTGLEALQFANIPPSLDQVLIANIDRSRLSNIRATFVIGANEGVMPATPTDEGMLSDEERDVLAAAGVELAPTTRQTLLEEQFVLYQMVTRASEKLYISCPLADEEGKTLLASSFMKKIKRMFPNVKETFVTNDVNDLSRAAQISYVTTPEVTLSYVMQQLQTWKRYGFEGDLDFWWDVYNFYVTSDEWKQKSNRVLSSLFYRNRAKKLSTAVSRILYGDKIKGSVSRMELFNRCAYAHFAQHGLSLRERDIFKLDAPDIGELFHAALKKIADKLLREKRTWADLSIKECEHLSILVIEEIAPLLQRQILLSSNRHAYLKQKLQQIIFRTSLVLREHAKASGFVPVDLEVPFGMGGKDSLPPMEFTLSNGVKMEVVGRIDRVDKAEDESGTFLRIIDYKSSSKALDLTEVYYGLALQMLTYLDVVISNAGTWMKQGEVASPAGVLYFHIHNPLVEVKGDASEEEIEKEILKKFKMKGLVLGDADVVRLMDNKLSTGSSDIISAGLKKDGSFSARSNIASEQEFSVLQKYVHHTFETIGKDITEGVIDIAPYKMGNKAACTFCHFRSVCQFDESLEDNQFRTLKDMKDSEAMEKIREEVGE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: RSMC_BUCAI
Sequence: MLLSKNSQLILRHRKKFKTKKVFFSGNIQDDFPLSLSTMRTKINFHKYNDCIDFKKKIMNNNIVHNNLLISQEMIQNCDVIIYYWPKDKSEAKFQLMNIISCSPINTEIFIVGNNSSGVKSAPLMLKKWIELEKIDSAKHSILISGLIKKKAIFVLEDFFKTHLWKNLIIKSLPGVFGHKKIDSGSKLLASTFSNRITGKVLDIGCGTGFLSASLLYFSPDAILTLVDNNMYALKCSQYTLNSNKFNGKIVYSNLYSNVFKKFDLIISNPPFHNDLQINFNIIEKMICGAKKYLTKTGELRFVTSRFINCHFLLNKFFQKYYVIKETSQYKVYQAFYK
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_POLNA
Sequence: MTRYSRITGTGSYLPPNRLTNAQLAAELAVKGVETSDEWIVERTGIKARHFAAPDVTSSDLGLEAAKRAIEAAGLQAADIDLIIVATSTPDMVFPSVACILQHKLGIAGCPAFDLQAVCSGFVYALTVADAMIKSGAASKALVIGAEVFSRILDFSDRTTCVLFGDGAGAVVLEASETPGILASDLHADGKHVGILCVPGHVSGGQVLGSPLLTMDGKAVFKLAVGVLESAARATLAKAGLLETDIDWLIPHQANLRIMHSTAKKLKLPLEKLIVTVDEHGNTSAASIPLALDEAVRSGKVKKGDILMLEGVGGGFTWGAVLLKY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_PSEA7
Sequence: MFAPLLKKLFGSKNERDVKRMAKAVQAINALEPQMVALSDEQLKAKTAEFQQRYAKGETLDQLLPEAFAVVREAGKRVMGMRHFDVQLIGGMTLHDGKIAEMRTGEGKTLVGTLPVYLNALSGKGVHVVTVNDYLARRDANWMRPLYEFLGLSVGVVTPFQPPEDKRAAYAADITYGTNNEFGFDYLRDNMAFSLDDKFQRELNFAVVDEVDSILIDEARTPLIISGQAEDSSELYIKINKLIPRLKRQVEEVEGKPSEEGHYSIDEKTRQVELNEQGHQFIEDLLSQNGLLGEGESLYSAHNLSLLTHVYAALRAHTLFHRNVEYIVQGDQILLIDEHTGRTMPGRRLSEGLHQAIEAKEGLPIQAESQTLASTTFQNYFRLYNKLAGMTGTADTEAFEFRQIYGLDVVVIPTHRPIARKDFNDLVYLTQEEKYAAIITDIKQCQALGRPILVGTASIESSEYVSKLLQQAGIEHKVLNAKYHEKEAEIIAQAGAPGSVTIATNMAGRGTDILLGGNWEVEVAALENPTEEQIAQIKAEWQKRHQQVIEAGGLHVIASERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDNLMRIFASDRVKNFMKALGMQSGEAIEHRMVTNAIEKAQRKVEGRNFDIRKQLLEFDDVANEQRKVIYHMRNTLLSAEDVGETIKEFREETLNATINQHIPPQSLPEQWDVEGLEAALYSDFAVRLPIQQWLDEDDKLYEETLRSKILEQIVAAYYEKEELAGAEALRAFEKQMLLRVLDDLWKDHLSTMDHLRHGIHLRGYAQKNPKQEYKRESFTLFQELLDSIKRDTIRVLSHVQVRREDPAEEEARLRREAEELAKRMQFQHAEAPSMEQAVAGEDEELPEGPAPVVPLEPVRNEQKIGRNEPCPCGSGKKYKHCHGQLD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RS3A_HUMAN
Sequence: MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).  May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).
What are the official names of this protein?
40S ribosomal protein S3a, Small ribosomal subunit protein eS1, v-fos transformation effector protein, Fte-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: IF3_BACFN
Sequence: MKNDSMKSQYRINEQIRAKEVRIVGDDVEPKVYPIFQALKLAEEKELDLVEISPNAQPPVCRIIDYSKFLYQLKKRQKEQKAKQVKVNVKEIRFGPQTDDHDYNFKLKHAKGFLEDGDKVKAYVFFKGRSILFKEQGEVLLLRFANDLEDYAKVDQLPVLEGKRMTIQLSPKKKESATKKPATPKPATPAAVKAEKPAGDNEE
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_AROAE
Sequence: MIGRITGILLEKNPPQIVVDTHGVGYEIDVPMSTFYGLPATGESLSLFTHLAIREDGHFLYGFASADERAAFRQLLKVSGIGARTALSVLSGLSVSDLAQAVALQETGRLVKIPGIGKKTAERLLLELRDKLGRALPGFGASTVPGAAAQPADSRSDILNALLALGYSDKEAQSALKAIPPETGVSDGIRQALKLLSKA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CYB_EULCO
Sequence: MNNIRKNHPLMKIMNNSFIDLPAPSNISSWWNFGSLLGACLALQIITGLFLAMHYTADTTTAFSSVAHICRDVNYGWIIRYLHANGASMFFLCLFIHIGRGLYYGSFTLTETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVLVHLLFLHETGSNNPLGISSDSDKIPFHPYYTIKDLLGLLLLILLTLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPILHTAKQRSMLFRPLSQCLFWTLTADLLILTWIGGQPVEHPFITIGQVASILYFTLILILMPMVSLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS6_METCA
Sequence: MRHYEIVFMVHPDQSGQVPAMIERYRSIIEGAAGRIHRLEDWGRRQLAYPIAKLHKAHYVLMNIECDQATLEELESGFRFNDAVLRSLTIRRDEAVTEPSALARSGSDAEADRAPADEGSVEAAGAEPGSEAEAEA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: 4EBP1_MOUSE
Sequence: MSAGSSCSQTPSRAIPTRRVALGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVAKTPPKDLPAIPGVTSPTSDEPPMQASQSQLPSSPEDKRAGGEESQFEMDI
What is the function of this protein?
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation.  In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (By similarity).  Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways (PubMed:7629182).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I.
What is the protein family that this protein belongs to?
Belongs to the eIF4E-binding protein family.
Protein: OGDHL_RAT
Sequence: MSQLRLLLFRLGPQARKLLATRDIAAFGGRRRSSGPPTTIPRSRGGVSPSYVEEMYFAWLENPQSVHKSWDNFFQRATKEASVGPAQPQPPAVIQESRASVSSCTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFRLPTTTFIGGSENTLSLREIIRRLESTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMKFSIEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGVENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGRKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHKQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTYPTTGIPEDTLSHIGNVASSVPLEDFKIHTGLSRILRGRADMTKKRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQDVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPVFTEDFEVSQLYDCNWIVVNCSTPASYFHVLRRQVLLPFRKPLIVFTPKSLLRHPDAKSSFDQMVSGTSFQRMIPEDGPAAQSPERVERLIFCTGKVYYDLVKERSSQGLEKQVAITRLEQISPFPFDLIMREAEKYSGAELVWCQEEHKNMGYYDYISPRFMTLLGHSRPIWYVGREPAAAPATGNKNTHLVSLRKFLDTAFNLKAFEGKTF
What is the function of this protein?
2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle (PubMed:18783430).  The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH (PubMed:18783430).  The OGDHC complex is mainly active in the mitochondrion (PubMed:18783430).  Involved in the inhibition of cell proliferation and in apoptosis (By similarity).
What are the official names of this protein?
2-oxoglutarate dehydrogenase-like, mitochondrial, 2-oxoglutarate dehydrogenase complex component E1-like, OGDC-E1-like, Alpha-ketoglutarate dehydrogenase-like.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FTSX_FLAJ1
Sequence: MSSNFDKFQKRRLISSYFSVVLSVFLVLFLLGVLGLFIINSKKLADDFKEKIAMTVFFKNEANDSIIKAFNSELKRAPFALSYVYVTKEKAAKEHTDIIGEDFLTFLGENPLLNSYDIHLKADYVERDSILKIESALRKNTMIEDIVYDKQLVNLVNDNIKKVSMWILIISGFLTVIAVLLINSSLRLSIHSNRFIIKTMQMVGATKSFIRKPFVMRSVKLGMLGALLAIIALIGLLFYVETNFPGLGILEDKALIGLVLLAVFGLGVLITWVSTHFATQRFLNLRTDDLY
What is the function of this protein?
Required for cell division and gliding motility.
What are the official names of this protein?
Cell division protein FtsX.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GFPL_ANEMA
Sequence: MALSNKFIGDDMKMTYHMDGCVNGHYFTVKGEGNGKPYEGTQTSTFKVTMANGGPLAFSFDILSTVFKYGNRCFTAYPTSMPDYFKQAFPDGMSYERTFTYEDGGVATASWEISLKGNCFEHKSTFHGVNFPADGPVMAKKTTGWDPSFEKMTVCDGILKGDVTAFLMLQGGGNYRCQFHTSYKTKKPVTMPPNHVVEHRIARTDLDKGGNSVQLTEHAVAHITSVVPF
What is the function of this protein?
Pigment protein that is green in color.
What are the official names of this protein?
GFP-like fluorescent chromoprotein amFP486.
What is the protein family that this protein belongs to?
Belongs to the GFP family.
Protein: EUTS_SALTY
Sequence: MNKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIMTLTPGETAMIAGDLAMKAADVHIGFLDRFSGALVIYGTVGAVEEALLQTVSGLGRLLNFTLCELTKS
What is the function of this protein?
Expression of the eut operon allows this bacteria to use ethanolamine as a carbon, nitrogen and energy source.  It relies on cobalamin (vitamin B12) both as a cofactor for the ethanolamine ammonia-lyase (EAL) activity and to induce the operon (PubMed:3045078).  EA enhances bacterial survival in macrophages in a concentration-dependent manner, suggesting it is an important nutrient during infection (PubMed:29531136).
What are the official names of this protein?
Bacterial microcompartment shell protein EutS, Ethanolamine utilization protein EutS.
What is the protein family that this protein belongs to?
Belongs to the EutS/PduU family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: SYTC2_DICDI
Sequence: MSFLKLTKSIQKINNFNNNKINLINKYFSTTNINNSGGGGNIKLNDGRIFKFEDKQTPLTIANKINKTIGKQSILSRLNGNKLISMKEIIEMSGKDYNIEFLNFEEHSDARICFWNSSSLVLARATMEYFKNENKEIELINFGHLVNPQTADNINQGTFYIDIFFKDKNQTIKDNDINKIKKIMEYIVKRNDKFEILKNDQQDQDQDQEESFIKFGEFKFKNNFLTIDSSNSIVSLDLIKNSSVVGPNKEYSELQRIVGISFPSKDQMNNWVEIQKIAALRDHRVIGKDQELFFFHPFSPGSCFFLPHGTKIYNKLLQFLRLEYRKRGYQEVISPNIYNQKLWETSGHWDNYKDNMFSFECDHTQYSLKPMNCPGHCLMYAHRARSYKELPMRIADFGVLHRNETHGSLSGLTRVRRFQQDDAHIFCTPDMIREEIKQCLDFMKYVYTIFNFTFHLELSTRPDSYLGELSVWEKAETSLSQVLTEFCGDKWTINHGDGAFYGPKIDIHLKDANGKNHQCATIQLDFQLPIRFNLEYSGGLNNNNNNNNNNEEINDNNNNNSLNRPVMIHRALFGSVERMMAILMEHTAGKWPFWLSPRQCIVIPVSNKFNQFAQEIQSKINLAGYDVDVDLNDSKLLSKKIREATVSQYNYIIVVGQEEIDTNILNVRKRDLPEDNKQVKLSLNDLFSEFKLNIEQFK
What are the official names of this protein?
Probable threonine--tRNA ligase 2, cytoplasmic, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_STRAW
Sequence: MTDIVDELKWRGLVALSTDEDALRKAFADGPVTFYCGFDPTAPSLHLGNLVQILTMRRIQQAGNRPLGLVGGATGLIGDPKPNSERTLNSREVVAEWVERLRAQIAPLLDFEGPNAAIMVNNLDWTQGLSAIEFLRDVGKYFRVNKMIAKEAVSRRLNSDAGISYTEFSYQILQGMDFLELYRRYGCTLQTGGSDQWGNLTSGTDLIHRAEPDAVVHALGTPLITKADGTKFGKTESGTIWLDPEMTTPYAFYQFWLNADDRDVSKFLRIFSFKSHEEIEELEKQTEERPQARAAQRALAEELTTLVHGADQTAAVIAASKALFGQGELTELDEATLAAALSELPHVKVAEPAPVVDLFAEVALVASKSAARRTIKEGGAYVNNVKVAAEDAVPAKEDLLHGRWLVLRRGKKNLAAVEVTGG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_SINMW
Sequence: MAMLPQEVIRKKRDGGRLVPAEIAGFIEGLADGSISEGQAAAFAMAVWFSGMSRDECVALTLAMRDSGETLDWGEFGRPVVDKHSTGGVGDNVSLMLAPIVAACGPVVPMISGRGLGHTGGTLDKLESIPGYNIQPSPELFRRVVDEVGCAIIGQTANLAPADKRLYAIRDVTATVDSVPLITASILSKKLAAGLQSLVLDVKLGNGSFMTDPAETEILARSLVEVANGAGVRTSALITDMNEPLADAAGNALEVENCLAYLSGKKAGTRLDRVVMAFAAEMLAAAGVSAHKAEGEAMARRALESGEALERFGLMVHRLGGPADFVERPEAYLERAPAIVPVAAARDGYLAACETRELGMAVIALGGGRRRPDDRIDHRVGLAGLRPLRTKVEKGEPIAFVHGADRDQAEAVAKRVATLYAIAEEAPAQRPVIASRLV
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: AGLM_HALVD
Sequence: MELSIIGSGYVGTTIAACFAELGHDVVNVDIDEDIVASLNDGQAPIHEPGLAELVERYAGDRLRATTDYDEILDTDATFLALPTPSTDDGSIDLGAMKTAATSLGETLARKDDSHLVVTKSTVVPRTTVDVIGPRIEEASGKRVGDGLDIAMNPEFLREGTAVDDFLSPDKIVLGAQTDRAYETLAEIFAPLVERAGNPPVVKTGISEAEMIKYANNAFLASKISLANDLANICKVFGVDSAEVLESIGLDSRIGSAFLGAGLGWGGSCFPKDTAAIIAAARAQGYEPRLLQAAVDVNDGQPERMLDLLRERFDLDGKRVAVLGLAFKPGTDDIRKSRAILLIQALLDAGADVVGYDPVATENMRERFPDIDYADSAADALANADAALVATDWDEFAALDDEFDAMRERIVIDGRRIVTRREGLDYESLV
What is the function of this protein?
Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins.  Involved in the biosynthesis of the hexuronic acids found at both positions 2 and 3 of the pentasaccharide.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase AglM, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH, Archaeal glycosylation protein M.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: DNAK_CLOPS
Sequence: MSKIIGIDLGTTNSCVAVMEGGEPVVITNSEGARTTPSVVSFQANGERLVGQVAKRQAITNPEKTIMSIKRHMGTDYKVNIDGKDYTPQEISAMILQKLKADAEAYLGEKVTEAVITVPAYFNDAERQATKDAGRIAGLDVKRIINEPTAASLAYGLDKMDSAHKILVYDLGGGTFDVSILDLGDGVFEVVSTNGDARLGGDDFDQRIIDYIAEDFKAQNGIDLRQDKMALQRLKEAAEKAKIELSSSTQTLINLPFITADATGPKHIDMTLTRAKFNELTHDLVERTIDIMKEALKSGNVSLNDIDKVILVGGSTRIPAVQEAVKNFTGKEPSKGVNPDECVAMGAAIQAGVLTGDVKDVLLLDVTPLTLGIETLGGVATPLIERNTTIPARKSQIFSTAADNQTSVEIHVVQGERQMAADNKTLGRFTLSGIAPAPRGIPQIEVAFDIDANGIVKVSATDKATGKEANITITASTNLSDAEIDKAVKEAEQFAEEDKKRKEAIEVKNNAEQIVYQTEKTLNELGDKVSAEEKSEIEAKIEEVKKVKDGDDIEAIKKAMEDLTQAFYKISEKLYQQNGGAQGEGFDPNNMGGANAGTGAANSNDDNVVDADFEVQDDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: BL1S4_HUMAN
Sequence: MEGSFSDGGALPEGLAEEAEPQGAAWSGDSGTVSQSHSSASGPWEDEGAEDGAPGRDLPLLRRAAAGYAACLLPGAGARPEVEALDASLEDLLTRVDEFVGMLDMLRGDSSHVVSEGVPRIHAKAAEMRRIYSRIDRLEAFVRMVGGRVARMEEQVTKAEAELGTFPRAFKKLLHTMNVPSLFSKSAPSRPQQAGYEAPVLFRTEDYFPCCSERPQL
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes.  In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.  The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension.  Plays a role in intracellular vesicle trafficking.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 4, BLOC-1 subunit 4, Protein cappuccino homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S4 family.
What are the subcellular locations of this protein?
Cytoplasm.