PharMolix/UniProtQA huggingface dataset:
Protein: CAS6_MYXXD
Sequence: MARSVGWRRSALITVSGCVILNWWGNLMVFVDLLFPVQGGPVPLDHAYLLFSALSRHLPALHERSDMGVFSLRGVSNTRELLYLGRGTMRLRCPIEAVATLLPLVSAPLEIAGRRLSLGAPSLHALEPVPSLFARLVTFKHAMDEAAFVAAASRALEALGVQATLKVGRRRIVRITGKKVVGFALELHGLSAEHSLRVQEQGMGGRRHMGCGLFLPPGRAARVQSHGKAA
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Processes pre-crRNA into individual crRNA units (By similarity).
What are the official names of this protein?
CRISPR-associated endonuclease Cas6.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family. Subtype Myxan subfamily.
Protein: GMHA_AZOVD
Sequence: MDMHARISQLFQASIETKQQAMEVILPHIVQASELMVQALLNEGKILSCGNGGSAGDAQHFSSELLNRFERERPSLPAIALTTDSSTLTSIANDYSYNEVFSKQIRALGQPGDVLLAISTSGNSANVIQAIQAAHDREMQVVALTGRDGGGMAALLLPEDIEIRIPAKVTARIQEVHLLVIHCLCDLIDNQLFGSEE
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_LIMF3
Sequence: MAKLTVEDLDLAGKKVLMRVDFNVPIKDGVVGDDNRIVAALPTIKYVLDHQGKAILFSHLGRIKKEDDKPGLSMRPVAERLSNLLNMPVTFVPVTEGPQLEDAIAKMEDGQVLVVQNTRYEDVKDGEYVKRESGNDPELGKYWASLGDLFINDAFGTAHRKHASNVGIASNMPGKAAAGFLMEKEIKFLGDAVTNPVRPFVAILGGAKVSDKIGVINNLLDKADKVIVGGGMTYTFYAAKGIKIGNSLVEEDKIDVAKEILEKAGDKLVLPVDNVVADKFANDANTKVVEGDIDDGWMALDIGPKSIEEFKKVLADAKTVVWNGPMGVFEMSNFAKGTLEVGQFLGTLEGATTIVGGGDSTAAAKQLGISDKLTHISTGGGASLAYLEGDVLPGIAAISDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_UREP2
Sequence: MKYKVMFFGTPEIAKIVLETLFNMHEVDLIAVVSQPDAHFDRKKNVIYSPVKQFCLDHNIKLFQPEKIKEIEEEIRILGPDIIITCAFGQFINQGIIDIPKYKIVNIHASLLPKLRGGAPIHYAILNGELKTGITLMHTIKKMDAGNILFQRSLEINDCTTTKSLTLELANLSALMIKEHFLELVKPNLVGIQQDENSVSFAYNIQKDQNIINFDQPAFFINRFVNAMYDKPIAIMQYNGVSIKVYQVKITNQKSCQKPGTIMIFKNQLFVSTQDFDIELLLIQLPNKKPLSPKVLLNGKNPFIN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DBP2_COCIM
Sequence: MSYGGGYSSSRDHYGGGHHSGGSGYRSGGYGGSNGYSHGNSNGYGSYGGNSHGSGVGSHGGGHHGDRMSNLGSGLKQQEWDLNALPKFEKHFYKEHPNVTNRSAQDVEAFRKEHEMTVYGKNVPRPVETFDEAGFPQYVISEVKAQGFAKPTPIQSQGWPMALSGRDVVGIAETGSGKTLTYCLPAIVHINAQPLLGPGDGPIVLVLAPTRELAVQIQAEITKFGKSSRIRNTCVYGGVPRGPQIRDLSRGVEVCIATPGRLIDMLEAGKTNLRRVTYLVLDEADRMLDMGFEPQIRKIIGQIRPDRQTCMWSATWPKEVRQLAHDFLHDYIQVYIGSQDLSANHRITQIVEIVSDFEKRDRMINHLERIMDDKKSKILIFTGTKRVADDITRFLRQDGWPALSIHGDKQQNERDWVLNEFKTGKSPIMVATDVASRGIDVRDITHVLNYDYPNNSEDYVHRIGRTGRAGAKGTAITLFTTDNAKQARDLVNILTESKQQIDPRLAEMARFGGGGGGGGRWGGRGRGRGGFTASNAAPLGHNRRW
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
What are the official names of this protein?
ATP-dependent RNA helicase DBP2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: O2T11_HUMAN
Sequence: MTNTSSSDFTLLGLLVNSEAAGIVFTVILAVFLGAVTANLVMIFLIQVDSRLHTPMYFLLSQLSIMDTLFICTTVPKLLADMVSKEKIISFVACGIQIFLYLTMIGSEFFLLGLMAYDCYVAVCNPLRYPVLMNRKKCLLLAAGAWFGGSLDGFLLTPITMNVPYCGSRSINHFFCEIPAVLKLACADTSLYETLMYICCVLMLLIPISIISTSYSLILLTIHRMPSAEGRKKAFTTCSSHLTVVSIFYGAAFYTYVLPQSFHTPEQDKVVSAFYTIVTPMLNPLIYSLRNKDVIGAFKKVFACCSSAQKVATSDA
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2T11, Olfactory receptor OR1-65.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PKN6_MYXXA
Sequence: MQIGKYQLVRKLASGGMAEVFLAKAAGPRGFEKTLVLKRILPHLAEDAAFVEMFLGEARLAAQLEHPNIVQIFDFGEAEGSFFLAMEFIDGPNLRKLVKRAAEEALPPAFCAKVVAAAAEGLAYAHEFRDVETGEPLGLIHRDVSPDNILVSRQGAVKVVDFGIAKVAGQGHRTLTGVVKGKVAYMPPEQLQAKAMDRRVDVYALGVVLYELLTGKRPFDATTDVSVMQAILFESFIPVSARRPDVPVALQQVLDKALAKDRERRYADCRALQDDLERFVLSTGEPVGAYQIAQRIAQWVPEVAAAPAMTPSQGGSKGAVASQAKADARSASMVSPPVDSTSPTTPMPRSLVAPVEVPADSTSPTTPMPVAIGGVVQALEPRSSPQQDTLQSYPVVVKTPALRADASARGASRPRAQSRASGVKVQAPQARDEDVVAMAAASSPPSGGASPAPTTPEDADDAVHTRSTEYAATVPSGRPGGRIAGIVGAVVALLVGGAVTVMRGDDSEVSPVRVNPPPLTHLPREPAVPSQGGRNVPQEKPAANVNAGARDSNDGAQAKPQVSTDVSVVPQEPHVARDATTPEAGLPTVKDAPPENGGAASKEGSAVVAKREPAKASGDPEPNPSRVRERAPTQKVAAVAKGRLEFRIRPYAVVSLDGKVLGQTPFAAVEVPEGRHTVRLVNKELGKDVTRTVDVKAGQATVFKLNLEAE
What is the function of this protein?
Pkn5 and pkn6 may have reciprocal roles in growth and development.  Pkn6 may be a transmembrane sensor of external signals for development.
What are the official names of this protein?
Serine/threonine-protein kinase pkn6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ISPG_PSEA7
Sequence: MSIHSASPITRRKSRKIWVGNVPVGGDAPIAVQSMTNTETCDVAATVAQIRRLEDAGADIVRVSVPDMDAAEAFGKIKQQVNVPLVADIHFDYRIALRVAELGVDCLRINPGNIGREDRVKAVVDAARERNIPIRIGVNAGSLEKDLQKKYGEPTPEALLESAMRHVDHLDKLDFQNFKVSVKASDVFMAVAAYRLLARQIEQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRISLAADPVEEIKVGFDILKSLHLRSRGINFIACPSCSRQNFDVVKTMNELEGRLEDLLVPMDVAVIGCVVNGPGEAKEAHVGLTGGTPNLVYIDGKPSQKLTNDNLVDELERLIRQKAAEKAEADASLIARG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL31_PSEF5
Sequence: MKADIHPVYEAITATCSCGNVIETRSTLAKPLSLDVCNECHPFYTGKQKTLDVGGRVDKFKSRFGAFGATKKA
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SHO1_AJEDR
Sequence: MARMDLNNIVGDPFALITISTSMIAWLLSFVTCVISDIQGLFPNFAWWAVGYMLCAIIGISIVLGSQTSHVYGVAIVGYLAAGLAFTSLAVNSLIYDDEASKQAAAAGFILQSMVIIVWIFYFGSSRHSSSRGYHDSMGAGKEQHHSYRNSKPISNNYGARPETTVSANQPPQMYTSAQLNGFETSSPVSGFPPTATNGADIQNRFGTTLGSQTNLGGGSTIGQDHQSTNEVSQPTEYPYRAKAIYSYEANPDDANEISFAKHEILDVSDVSGRWWQAKKASGETGIAPSNYLILI
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DUF4_ARATH
Sequence: MFLTNGSRAGPVKERGLLIIDADHPNYDASGRGKRRRVEQEHHSDLNNETAAPTGGSAGEEIVLPFTKTLASWKEFESDEVYKRTPQRPHFPSLAYTHPSFGEPTAAYLTAAFIDCVKTVDGMCEDTPKSELDVYRETFKMFEEQGFDVAEPLSQVLTLLVLRKMRRESLRQQKGMEKEMADDYSKLKKSLVRCKSSFEDKETAK
What is the function of this protein?
May be involved in the polar growth of plant cells via transportation of RNAs.
What are the official names of this protein?
DUF724 domain-containing protein 4, AtDUF4.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEGN_RAT
Sequence: MDNAHRQTQAHLDAACFWQIWQRFDKDEKGYIKETELDAFFDDLLAKFGIEDTLMEENVQKMKEQLMVGHDISKEGRILMKELASMFLSEDENFLLFFRLETPLDNSVEFMQIWRKYDADSSGFISAAELSNFLRDLFLHHKKVISEAELEEYTSTMEKIFDRNKDGRLDLNDLARILALQENFLLQFKMDASSTEERKRDFEKIFAHYDVSKTGALEGPEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP
What are the official names of this protein?
Secretagogin.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions. A small proportion is detected in the medium of cultured insuloma cells. Dexamethasone promotes the export into the culture medium.
Protein: CDD_VIBC3
Sequence: MRNRIEQALQQMPASFAPYLRELVLAKDFDATFSAEQYQQLLTLSGMEDSDLRVALLPIAAAYSYAPISEFYVGAIVRGISGRLYLGANMEFTGAQLGQTVHAEQCAISHAWMKGEKGVADITINFSPCGHCRQFMNELTTASSLKIQLPKRAAKTLQEYLPESFGPADLGIDSGLMSPVNHGKTSDDDEELIQQALRAMNISHSPYTQNFSGVALKMRSGAIYLGAYAENAAFNPSLPPLQVALAQAMMMGESFEDIEAAALVESATGKISHLADTQATLEVINPDIPLSYLSL
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: NU3C_PROM5
Sequence: MFSLPGYEYFLGFLIIAAAVPILALVTNLIVAPKGRTGERKLTYESGMEPIGGAWIQFNIRYYMFALVFVIFDVETVFLYPWAVAFNRLGLLAFIEALIFIAILVIALAYAWRKGALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: NOD4B_XENLA
Sequence: MHLYFSCFILLFVPGGKSLGINSHLKHMSNKSQDQVNRTRTVGSKDVAALPLSSYMFNLYQSFHHSELNHGMEAAPSLSLNHRADIIRSLAVKSYDHGGSLWTFLFDFSSLSQEEEHQFAEVRFDFRAFSDAILVGMEVIVDFFHQSSTCQSISGFCQSYLYVGSLTSTLWPRSSDTWVTFEATDIIHKWFERNDKGKNHSEGHMKQPKKLHRAKSAERRYQQRSTENPQILMMVYSNISKKEKLSGTATLLQDAAHSKYLAVMPGIQTIANSRRHRRSHIFNEHIMGMKHVPSADSSRTLCRRVDFFVDFKQIGWDSWIIHPVKYNAYRCEGECPSPVNERLKPNNHAYMQ
What is the function of this protein?
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos.  Plays a role in mesoderm formation and may be required for neural development (By similarity).
What are the official names of this protein?
Nodal homolog 4-B, Nodal-related protein 4-B, Xnr4.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUKF_HAEIN
Sequence: MIETSQTIPELVSWAKDREFSLNLPTERLVFLLAIAIYNNERLDGEMLEADLVDIFRHTMNAFEQSTDAIATRANNAINELVKQRLLNRFSSEFTEGLAIYRLTPLGVGVSDYYIRQREFSALRLSVQLSIVADEIQRASDSAEEGVENNENEHYWRRNVFAPLKYSVAEIFDSIDLSQRIMDENQQSIKDEIAELLTKDWQAAISSCERLLDETSGNLRELQDTLNAAGDKLQAQLLRIQDCVIGRDDLYFIDQLITDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFSQRLRNSIHHYFDHPWFLWTAQAERLVDLRDEEMVLREDDALGELPEELQYESLSDLHDQIVEHMQGLLIAYRENNRPIDLSLVLKEQLENYPLSRHFDVARIIVDQAVRLGMANDDLSGIYPDWQAINKRGAEVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: S41A2_MOUSE
Sequence: MTHSKGRPVTYKTSASPESGGGFVDWTLNLNTIQSDKFLNLLLSMVPVIYQKNQEDRHKKVNGIWQDGLSGAAQTFSKRSEPHLDYHEFSEQAFHSSSSGHTPASCSPKYDDYAGYNYCDGREASETTAMLQDEDLSSEGDDVIVETSQRIPKESSGVMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFKNVTEVFILVPALLGLKGNLEMTLASRLSTAVNVGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLSHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVCAFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPEEPKGCSYPFRTFFGSGVNNKSAQVLLLFVIPGHLIFLYTIHLMKSGHTSLTVVFVVVYLFAAVLQVFTLLWIADWMVHRFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD
What is the function of this protein?
Acts as a plasma-membrane magnesium transporter.
What are the official names of this protein?
Solute carrier family 41 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC41A transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSX_HERA2
Sequence: MRIVLDASGGDHAPQATVAGAIAAARTWGDQIILVGDEASIRAELAKHDTSNLDLPVVNAPEMIEMTEHPAQAIRRKRNSSVAIGLRLVRDGEADAFVSAGHSGATMAGALFILGRIRGIERPCLVTHFPTVHGHALLLDSGATTDCKPEYLVQFAQMGNVYAQKIVNIAMPRIGLLANGEEANKGDKLVQDTHVLLQQRSDLTFIGNVEPKDMLINGSADVVVADGFVGNLVLKFGEGVFKMITTAASNNIKAEWRKNLVLGLLPALVALTLPGKGRWRALIAGLTGLTLPASMAVAPLLALRKRMDYRSHGGAPLLGVNGIAIVAHGKSDALAIQNAIGQARNAVEQRVVATISHALETVELVPSA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: NU4LM_AVACL
Sequence: MTPIFTNIILAFATAFLGTLIFRSHLMSSLLCLEGMMLSLFILSTLIILNMHLTVSFMMPILLLVFAACEAAIGLALLVMVSNTYGLDYIKNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: THIG_PSEA7
Sequence: MSQASSTDTPFVIAGRTYGSRLLVGTGKYKDLDETRRAIEASGAEIVTVAVRRTNIGQNPGEPNLLDVIPPDRYTILPNTAGCYDAVEAVRTCRLARELLDGHNLVKLEVLADQKTLFPNVVETLKAAEQLVKDGFDVMVYTSDDPIIARQLAEIGCIAVMPLAGLIGSGLGICNPYNLRIILEEAKVPVLVDAGVGTASDAAIAMELGCEAVLMNTAIAHARDPVMMAEAMKHAIVAGRLAYLAGRMPRKLYASASSPLDGLID
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTLA_STAAU
Sequence: MNREEVQLLGFEIVAFAGDARSKFLEALTAAQAGDFAKADALIEEGNNCIAEAHRAQTSLLAKEAQGDDIAYSVTMMHGQDHLMTTILLKDLMKHLLEFYKRG
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport, but can also use galactose, isopropyl beta-thio-galactopyranoside and thiomethyl beta-D-galactopyranoside (TMG) as substrates.
What are the official names of this protein?
PTS system lactose-specific EIIA component, EIIA-Lac, EIII-Lac, Lactose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_SOLM1
Sequence: MLILTRRPGESLHLGDHIKITVLGVQGKQIKIGLEVPDDMQVYREEVYLRVLEQNRQALCAMDSDVLAAAKLWPKKTNE
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_AGARV
Sequence: MNVIEGKMTQDGIKVGIVVARFNEFITSKLLGGAKDGLVRHDVPEENIDVAWVPGAFEIPLIAKKMAKSRKYDAIICLGAVIRGATSHYDYVCNEVSKGIASVSLESEIPVMFGVVTTENIEQAIERAGTKAGNKGYDCALGAIEMINLVRQIG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RHDF2_XENTR
Sequence: MASLKKNGSSSRLQDRKPPNLSITIPPVEGERDPKLMQPLTKPVFQKSVSLQEPRGHVAEGGTADVRPGFKRQTSLSQSIKRGTAQWFGVSNDWEGKRQQWQRKSLHHCSLRYGKLKPQYQRDIELPSQETPSFQATESPATHRLPKIVDPLARGRPFRHPDEVDRPRTPHVGLPPQTPGMLSLASFTSVRSGYSRFPRRKRESVAHMSFRAAAALIKGRPILDTPHSRKAGQKRSFIYPSFMDEDTVDAAETLDSSFFSKVDMHDETFSMPDDVFDSPPMSASYFRAPLPIPELMPGAAIEAAKEPVKSVQVYTPDHRRGKRIASQVKHFAFDRKKRLYGLGVVGSWLNRTYRRSISSTVQSQLEHFNSHRPYFAYWITFVHILITILAIATYGIAPIGFAQHTTSELVLRNKGVYESVKYIQQENFWIGPSSIALIHLGAKFSPCIRYDEQIKNLIEKQHGLERESGCCIQNDKSGCVQTHRKDCSETLATFIKWPEHDAPVLDEVTGMKRTSGAVCHQDPRTCEEPASIQPHVWADDITKWPICTYQAMNNHTGIRHMDCEIKGRPCCIGTKGSCEITTREYCTFMHGYFHEEATLCSQVHCLDEVCGLLPFLNPEYPDQFYRLWLSLFLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFLPYRAEVGPAGSQFGLLACLFVELFQSWQILAKPWKAFLKLLGIVLFLFLFGLLPWIDNIAHIFGFLSGLLLSFSFLPYITFGTADKFRKRAMIIISLLVFVGLFASLVIWLYVYPINWAWIEYLTCLPFTNKFCEKYDIDQVLH
What is the function of this protein?
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation.  Does not exhibit any protease activity on its own.
What are the official names of this protein?
Inactive rhomboid protein 2, iRhom2, Rhomboid family member 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.
Protein: DYRK2_CHICK
Sequence: MNEHLHVGSHGQIQVQQLFEDNSNKRTVLTTQPNGLTTLGKSGLPVVQDRQSESAHRRQGSSSSLKSTDGTGKVKASVMTPEQAMKQYMQKLTTFEHNEIFGYTEIYFLGPNAKKRQGVIGGPNNCGYDDDQGSYIQVPHDHIAYRYEVLKVIGKGSFGQVVKAYDHKMHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNNMNVIHMLENFTFRSHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSPKLLDSSKRAKNFVSSKGYPRYCTITTLSDGSIILNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAIRMTPSQALRHPWLRRRLPKPPTGEKASAKRITESTGAITSISKLPPTSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS
What is the function of this protein?
Serine/threonine-protein kinase involved in the control of mitotic transition and the regulation of cellular growth and/or development.
What are the official names of this protein?
Dual specificity tyrosine-phosphorylation-regulated kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PEPC_LISIN
Sequence: MSTEITFDQLESFSKKWRENPDKLVFQASIMKNGIKAATENPVSKATVQPVFSHEVHTDKVSNQQQSGRCWMFAALNTFRHKLNGTLGLKDFELSQNYTNFWDKLEKANYFLENIIETANEDEDSRLVSWLLDTPQQDGGQWDMLVSIIEKYGVVSKSAMPETFQSSKSADLNHLLNERLRTDAVILRKAVKEQKDTAGLKEEMLAEVYQLLVMTLGEPPKVFDFEYRNKDNEFKQDLQITPKEFYKRYVDMDLKDYIPLINAPTKDKPFNQAFTVDYLGNIVNGTPIKYLNVEMDVLKKATADQIKDGETVWFGCDVGQLSERTTGIMDTDIFLLNQAFGFKTAMTKAERLDYKHSMLTHAMVLTGVNIVNNEVNRWKVENSWGEKIGNNGYFVASDAWMDEFTFQVVVHKKYLSKELIEAFSNEPIALKPWDPMGSLAL
What are the official names of this protein?
Aminopeptidase C, Bleomycin hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: ZN649_HUMAN
Sequence: MTKAQESLTLEDVAVDFTWEEWQFLSPAQKDLYRDVMLENYSNLVSVGYQAGKPDALTKLEQGEPLWTLEDEIHSPAHPEIEKADDHLQQPLQNQKILKRTGQRYEHGRTLKSYLGLTNQSRRYNRKEPAEFNGDGAFLHDNHEQMPTEIEFPESRKPISTKSQFLKHQQTHNIEKAHECTDCGKAFLKKSQLTEHKRIHTGKKPHVCSLCGKAFYKKYRLTEHERAHRGEKPHGCSLCGKAFYKRYRLTEHERAHKGEKPYGCSECGKAFPRKSELTEHQRIHTGIKPHQCSECGRAFSRKSLLVVHQRTHTGEKPHTCSECGKGFIQKGNLNIHQRTHTGEKPYGCIDCGKAFSQKSCLVAHQRYHTGKTPFVCPECGQPCSQKSGLIRHQKIHSGEKPYKCSDCGKAFLTKTMLIVHHRTHTGERPYGCDECEKAYFYMSCLVKHKRIHSREKRGDSVKVENPSTASHSLSPSEHVQGKSPVNMVTVAMVAGQCEFAHILHS
What is the function of this protein?
Transcriptional repressor.  Regulator of transcriptional factor complexes and may suppress SRE and AP-1 transcription activities mediated by growth factor signaling pathways.
What are the official names of this protein?
Zinc finger protein 649.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AIM46_YEAS7
Sequence: MRLISKVLVKTNCLEVGMRRAPQWYSHYSTTAGNARVNKKGSKVVPVLTGLALASIFAKKWYDDSQIKKADVTSVAVDASISAFPKKMGPPQWPFSTQYELIGKGVRCVSSITFKAYGLGIYVAAEDKHLVSEVLDSKFLSQAFIDTAAPPSPENSHQDNLRAALNDPAKAPILINNLLDSGIRLMSKNTPIKAGSFKLLMDGTKKSVLKNPDSQSQDKDRLEAGFQELHDCFRSVKGLVARDDDFFIELNKDCSMNLSYYARKKDEFVILGTVKEPLIGKLLFAHYLAAVDPPSPEARKEVIDALVSLS
What are the official names of this protein?
Altered inheritance of mitochondria protein 46, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM18/AIM46 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DAO_MYCTU
Sequence: MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGAVWGPRPKEPVAKVRGWIEQSLHVFRDLAKDPATGVRMTPALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLPMIDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEAAPIVINCAGLGARELAGDATVWPRFGQHVVLTNPGLEQLFIERTGGSEWICYFAHPQRVVCGGISIPGRWDPTPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLSWGCAREVVNLVGGG
What are the official names of this protein?
Probable D-amino-acid oxidase, DAAO, DAMOX, DAO.
What is the protein family that this protein belongs to?
Belongs to the DAMOX/DASOX family.