PharMolix/UniProtQA huggingface dataset:
Protein: PAN2_MOUSE
Sequence: MNFEGLDPGLAEFSPAMHSTLDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGGDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSVLLTDNSTLLVGGLQNHVLEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRSFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDALLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDHEFDNFSQVTESPTGREEEPLHTVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGSNFLRAFRTIPEASALGLILADSDEASGKGSLARLIQRWNRFILTQLHQDMQELEVPQAYRGAGGSFCSSGDSIIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPEDKTGKNYDFAQVLKRSICLEQNTQAWCDNCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRLQAEVAFKIAVKKYGGEMKSKEFALADRKELRSPEGFLCSSIEELKNVWLPFSIRMKMTKNKGLDVCNWADEHELSSLGAPSQWGPARAEEELGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKYEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQVGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPESQTSPKNAAVFSVLAL
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP).  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1 (PubMed:16284618).  Also acts as an important regulator of the HIF1A-mediated hypoxic response.  Required for HIF1A mRNA stability independent of poly(A) tail length regulation (By similarity).
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit Pan2, Inactive ubiquitin carboxyl-terminal hydrolase 52, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Nucleus. Note=Shuttles between nucleus and cytoplasm.
Protein: QUEC_MARN8
Sequence: MTDSVVVIYSGGMDSFTLLHLARARGLKVHALSFNYGQRHVRELDVAADVCRAEGIPHKVIDIRAMSEVMSGSSLTSDIEVPEGHYEEDTMKATVVPNRNMILLSLATGYAVTTGAGAVWYGAHGGDHAIYPDCRPEFVEKMDAVCRVANYEPVGIEAPFMAMDKGQILAEGLKLGLDYSQTWTCYNGRDKACGRCGSCVERLEAFAANGVTDPLAYERLA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: TATB_HAHCH
Sequence: MFDIGFPELALVAVIGLLVLGPERLPYAARKTGLWVGRIRRMVSQMSSEIDRQLKAEEMRERLRKEGDTLGLEKIQQTVNEALAEAKKYEDMVEKNPATPMSSKASTPQTPSSGPDPQPVESHSHSDDASKQHDRS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AIM32_SACKU
Sequence: MLRTTVRTLQQQAFLHHSFERVSLPELHSTIKDVQTTCYCQNINARLPSTTDPLDPQIRLSDRTPYYNKHVLLVSPGDKFAQPWKIAWNHNLDTNLNRPYNAISKLRSYLGKSPGILINAVHLQNDFIPRPKEDDEWLFFFVIPDMKLYKISETDLEQFASFLNEGVVQAPRLSFQDYLIGKARVPQETHKVHHKNLTKFQGDILLRDWSLVCGHYKRDAKCGEMGPDIIAAFQDEKLLTDNNLGLISHVGGHVFAGNVIFYKLFKAENALNKLDSLWFGKVYPHNLKLLCENLENGKIIDEMYRGGISMN
What are the official names of this protein?
Altered inheritance of mitochondria protein 32.
What is the protein family that this protein belongs to?
Belongs to the AIM32 family.
Protein: RSMA_AERPE
Sequence: MPPGSGRGGRRRAESLVREVLGLAGLRPSDRLGQHFLIDDRAVGEFLKPLEKAAAEGIREALEIGPGAGSITLPAAEVLDRIVAVELDNRLASALSRLAPARVAVITGDGVSHAAASQAPLVFSNTPFNLSPAIVEALAVNNRVAAAVLGVQYEVARRMTARPGSRDYSRLSVLVSLVFHAELAGVVRPQAYYPRPQVLTAVVTLRRRRRWRSLYARALELAGCAFTQRNKKASKVLRRCLEAAGCAPPPWLDSLGDARVWMLRPEDFVGLAEACRG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits (By similarity).
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT_NEUCR
Sequence: MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPHAIARVDMAGRDLTDYLMKILAERGYTFSTTAEREIVRDIKEKLCYVALDFEQEIQTAAQSSSLEKSYELPDGQVITIGNERFRAPEALFQPSVLGLESGGIHVTTFNSIMKCDVDVRKDLYGNIVMSGGTTMYPGLSDRMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YHEU_ECOHS
Sequence: MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKRQLQCGEAVLVWSELHETVNIMPRSQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: CAS1C_RHORT
Sequence: MVGSGGTGAPPPRSSPMTTLYVTQPGSVVRSEGGSLTVWVETEADDPGPNDSPVRRKRLASVEPHRLESLVLLGFTTITANAMRLCMANKIAVSLLDGGGGLAARVVPPEARSADLRLHQYALHLDPPERLIRARAVVTAKLRNAAAVLRGIRSNQASSAALASAITQTEASAEAAAAAVSAESLLGIEGNGAHQYFAGLRTAFVGGIPFLGRAQRPPPDPANSLLSFGYVLLGNRLTGLLEARGVDPCLGFFHDLRPGRPSLALDLLEELRHPVVDRLALRICNLRKIQPQHFEPDAERPGGVKLTVDGRKIFLEEWEGHLARPLREPGVAAEHRLDVHRLLQRQVDRLVSDLRGGEPYRPFRFGTSRPG
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1 3.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: RHLB_PSESM
Sequence: MEPQEGKTRFHDFNLAPELMHAIQDLGFPYCTPIQAGVLGFTLKGKDAIGRAQTGTGKTAAFLISIIEQLTQTPPPAERYMGEPRALIIAPTRELVVQIAKDAADLTKYTNLNVMTFVGGMDFDKQLKQLEARHCDILVATPGRLLDFNQRGEVHLDMVEVMVLDEADRMLDMGFIPQVRQIIRQTPHKGERQTLLFSATFTEDVMNLAKQWTTDPSIVEIESLNVASDNVEQHIYAVAGADKYKLLYNLVTDNGWERVMVFANRKDEVRRIEERLVRDGVNAAQLSGDVPQHKRIKTLEGFREGKIRVLVATDVAGRGIHIDGISHVINFTLPEVPDDYVHRIGRTGRAGADGVSISFAGEDDSYQLPAIEEKLGRKISCETPPTHLLRAVVRQTN
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_ECOHS
Sequence: MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRNIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQLVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFIMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQCEILR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CINAL_DESOH
Sequence: MIAEILATGNEVLSGTIADTNAAHIAQILEAAGIEVRRHTCVGDDLDHIAAAVTEICARADVLLVTGGLGPTGDDLTTAAVARAAKKKLVLDPDAEHSMKTYFVQRKRSMQPSDAKQAMLPEGAQCIVNDIGTAPGFMLAMGHCHVFVMPGVPHEMKQMLETGVMPRIETLQGGGRLYAASRTLTVFGLPESTVGERMAGFGAALPGMRYGIRVRFPEIFIKVSTRQPDSRTAQDLAGQACQWVKKQVGESVFSDAGLALEAEVGRLLVSAKATVAVAESCTGGLIADLLTGVPGSSDYFLFSGVTYANQAKVDVLGVSPQTIETHGAVSEETVKEMADGVRRVAGATFGLATSGIAGPSGGTKEKPVGTVCIGLAGPDGVQTSHVCLSFQNRSMNKRLFAFLALETLRRKLL
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: NU5M_SCYCA
Sequence: MNTIFNSSFLLIFITLMIPLVTSLSPKKLNPSPSSFYVKTAVKISFFISLIPLFIFLDQGLESIVTNWNWMNMGPFNINMSFKFDLYSIMFTPVALYVTWSILEFALWYMHLDPNINRFFKYLLLFLISMIILVTANNMFQLFIGWEGVGIMSFLLIGWWYSRTDANTAALQAVIYNRIGDIGLILSMAWLAMNLNSWEIQQIFILSKDKDLTLPLLGLVLAAAGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRLHPLIQDNQFILTTCLCLGAITTLFTATCALTQNDIKKIIAFSTSSQLGLMMVTIGLNQPQLAFLHICTHAFFKAMLFLCSGSIIHSLNDEQDIRKMGGLHKLLPFTSSSLTVGSLALTGMPFLSGFFSKDAIIEAMNTSHLNAWALILTLVATSFTAIYSLRLIFFTLMKFPRFNSFSPINENNPMVINPLKRLAYGSIIAGLIITSNLPPAKTQIMTMSPLLKLSALLVTILGLLLALELTNLTHSQFKIYPTFPYHHFSNMLGYFPPIIHRLLPKINLNWAQHISTHLIDQTWNEKIGPKSTLIQQIPLIKLSTHPQQGYIKTYLTLLFLTLTLIILVVFI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ZG16_HUMAN
Sequence: MLTVALLALLCASASGNAIQARSSSYSGEYGGGGGKRFSHSGNQLDGPITALRVRVNTYYIVGLQVRYGKVWSDYVGGRNGDLEEIFLHPGESVIQVSGKYKWYLKKLVFVTDKGRYLSFGKDSGTSFNAVPLHPNTVLRFISGRSGSLIDAIGLHWDVYPSSCSRC
What is the function of this protein?
May play a role in protein trafficking.  May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN.
What are the official names of this protein?
Zymogen granule membrane protein 16, Zymogen granule protein 16, hZG16, Secretory lectin ZG16.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Zymogen granule lumen. Golgi apparatus lumen.
Protein: DAPD_NITMU
Sequence: MDQLQSTIEEAFERRAEMTPRNVEAKLKESITQVLEMLDSGKLRVAEKTDGEWKTHQWIKKAVLLSFRIEDNSFIKGGFSNYFDKVPSKFADYSSRDFRNGGFRVVPPATVRKGAFIASNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPVQANPTIIEDNCFIGARSEVVEGVIVGENSVISMGVYIGQSTRIYNRETGEISYGRIPPGSVVVSGSLPSADGKYSLYCAVIVKQVDAKTRAKTGINELLRGI
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PSEAB
Sequence: MLQPKRTKFRKQMTGHNRGLAHRGSKVSFGEYALKATSRGRLTARQIESARRALTRHVKRGGKIWIRVFPDKPVTKKPLEVRMGKGKGGVEYWVAQIQPGKVLYEIEGVSEELAREAFALAAAKLPLATSFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SETMR_BOVIN
Sequence: MATCEEVPEALKGQLDVARGLENLPVSAWPPGAEPEPFQYTPDHVAGPGADADPSQITFPGCACLKTPCLPGTCSCLRHENNYDDRSCLRDIGSEAKCTEPVFECNVLCQCSERCRNRVVQWGLQFHLQVFKTDHKGWGLRTLDFIPKGRFVCEYAGEVLGISEVQRRVQLQTIHDSNYIIAIREHVYNGQVMETFVDPASIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAARDILPEEELSYDYSGRFLNLMHSEDKERLDNGKLRKPCYCGARSCAAFLPYDSSLYCPTEKPDTSEEGRA
What is the function of this protein?
Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation.  Specifically mediates dimethylation of H3 'Lys-36'.
What are the official names of this protein?
Histone-lysine N-methyltransferase SETMAR, SET domain and mariner transposase fusion protein homolog.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL15_STRPS
Sequence: MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIVKAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RL2_SHEPW
Sequence: MAVIKCKPTSPGRRHVVKVVNSDLHKGKPFAGLLAKKSKSGGRNNTGRITSRHIGGGHKQHYRLIDFKRNKDGIPAKVERLEYDPNRTANIALVLYADGERRYIIAAKGMKAGDSIQSGIDAEIKSGNAMPLRNIPVGSVVHAVEMKPGKGAQIARSAGAYVQVIARDGAYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGQPTKGYKTRSNKRTDKYIVRRRNKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HSP70_HYDOL
Sequence: VLLKMKEIADAYLGKKVTDVVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPNAAAIAYGLDKKVEKEKNVLIFDLGGGTFDVSILAIEDGIFEVKSTAGDTHLGGEDF
What are the official names of this protein?
Heat shock 70 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GRPE_MESM1
Sequence: MIINYKFSDFYFDKKLSGKEVEFSIQIQKREASSDKNLQSKNLIIDAINVQRDFSEKNKSSDNLEILNKQIEDKNDLIINLEKKVFDLTLENKKNIDDFNEKAKSFAKKAQEELDKYKLELKSFLENEFEEKKKFSFQKLFENIINPLNNFRLAIDAGSKQENSSIKSYVQGFEMLLNQTINILESYGLIIIRPEIGDTFNPEVHNAVELREEGTPNRILKINSLGYQFHERVLKPASVIVSK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
Protein: RNY_ALKCK
Sequence: MPSYTLSLLVLCLIVLAFSVVFAVVGYLVRKSVAEAKISSAEHAAKQMIDDAKREAETNKKEAILEVKDEVHKLRSDAEREVRERRNEIQKQEHRLVQKEEILDRKSETLDKKEESLEKREESLAKKQRQVEEMESKMSQLLVEQKQELERVSGLSREEARMIIRQEVEQEIAHETALLIKEKTAEAKETADKRSKEILSLAIQRCSADHVAETTVSVVNLPNDEMKGRIIGREGRNIRALETLTGIDLIIDDTPEAVILSGFDPIRREIARSALEKLVQDGRIHPARIEEMVDKSRREVDETIREYGEQTTFEVGVHGLHPDLIKILGRLRFRTSYGQNVLKHSMEVAHLAGIMAAELGEDVKLAKRAGLLHDIGKAIDHEVEGSHVEIGVELATKYKEHPVVINAIASHHGDTESTSIISTLVAAADALSAARPGARRETLETYIRRLEKLEEISESFDGVEKTFAIQAGREVRIMVRPDVVDDALAHKLARDITKKIEQELDYPGHIRVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DAPF_LISMO
Sequence: MATIHFTKVHGSQNDFFLVDEEGNQIMDWSDAKRADFAIKLCDREHSLGGADGILYVTKSSEAGPIGQMRVVNSDGSIASMCGNGLRTVARYLLEKHALTEAKVETMKAILDVKKATSLGFDIPTYQVEISPVKFNAESLPMNVGVEKLFNQVVPELDAELAFSAVSVPNPHLITFVDQTVLDSDRQETLASYLNSENPYFPDGVNVSFVKRLSDDAIYVRTFERGVGFTNACGTAMSACSLIKKMLDKDTFETPLNVYNDGGRVQVTAKKDEAGDISLQLIGNATFVSTGSVSYESDTVTELTNEATPEQAQYQELVKEVKEFLKTTE
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAB1_STAS1
Sequence: MTYSIGIDYGTASGRVFLVDTTNGEIISTYIKEYPHGTISESLNGTELPHNYFLQHAADYTSILEEGVQYVLKDSQVDPKSIIGIGIDFTSCTIVFLDDDFKPLHLHPDLEDQPHAYVKLWKHHGAQDEATYMKQVSDKVNPSWLNFYGHNVNSEWMIPKILEVKNKAPEVLERSAYIMEAGDYLVSLLTDKNIRSNCGIGFKGFYNETDGFNYSFFEAIDQELPEIVKTKCESPVVNIGESAGSLSPYYQNLWGLTEQVQISPYIIDAHSGVLGVGAIEQGEFTPVIGTSTCHLMLDPKQEPIPAITGSVKDAIIPGLYAYEAGQAAVGDLFNYSASLAPKSYVDQAEKQGLSILGYLEKLAADISIDKQHVTVLDWHNGNRSILSDSKLTGSIFGLTLQTPFEMIHKAYLESTAFGTKMIMQQFENNHIPVETVYAAGGIPIKSELLVDIYANVLNKEVVVIDSSNATALGAAMLGANVGGAYPTLKETVKHMKQPVYYRKQPEAKKVKQYALLFDRYKALHDLLGKEYPQLSYIN
What are the official names of this protein?
Ribulokinase 1.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: Y3946_NOSS1
Sequence: MQQSLLTFEQVYYTYPGTQQSVLNGITLQIPQGKRCALIGRNGCGKTTLFSLANGLYKPQQGRVYWQEKALQYDRKNLMQLRQKVGLVFQNPEQQLVASTVEEDISYGLCNLGLPIADIQQRVTQALVEFELTELAERPVHHLSLGQKKRVSLADVMVLRPELLLLDEPTAYLDRPQSRNLMAMLNKIYKSGTTILMASHDLDLVYCWSDWVFVMDAGRLILEGKPEDIFSQREILDSIELGLPPIYEIFITEELATKEHNSENFRRRILQFFC
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein alr3946.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KAPC2_CAEEL
Sequence: MVILSHHKRSPPLLMRLFRICRFFRRLMSSSTSSVESVEDESCSNECSASFTFDTNNNSRGNNQVNELAEETHMKLSITPTRESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICGTPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDDYEEDTTGGPLCSQRDRDLFAEW
What are the official names of this protein?
cAMP-dependent protein kinase, catalytic subunit-like.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. cAMP subfamily.
Protein: OTC_NEIME
Sequence: KTSTRTRCAFEVAARDQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDAIEYRGFGQEVVEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMGNSLLILGAKLGMDVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKNVDFIHTDVWVSMGEPKEVWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTEEVFESPASIVFDQA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HJC_SACS2
Sequence: MNAKKRKGSAVERNIVSRLRDKGFAVVRAPASGSKRKDPIPDIIALKNGVIILIEMKSRKDIEGKIYVRREQAEGIIEFARKSGGSLFLGVKKPGVLKFIPFEKLRRTETGNYVADSEIEGLDLEDLVRLVEAKISRTLDNFL
What is the function of this protein?
A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination; may have some degree of sequence preference in a mobile junction.  Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.  Can cleave all 4 strands 3 bases 3' of the junction center.  Cleaves both mobile and immobile junctions.  Modifies the structure of the 4-way DNA junction, a model Holliday junction structure.  The protein forms multiple complexes with 4-way DNA, suggesting more than 1 homodimer can bind to each junction.
What are the official names of this protein?
Holliday junction resolvase Hjc, Hjc.
What is the protein family that this protein belongs to?
Belongs to the Holliday junction resolvase Hjc family.
Protein: Y2383_ACIAD
Sequence: MLMSQFDVNLLVLLVLLACGIFSQNAAVTIAAGVLIVFKLTPLSEFFPFLQQHGLNVGVIILTIGVLTPIASGKLSGETILKSFFSYKSILAITVGLLVAWLGGRGVKLMSSQPDIVAGLLIGTVAGVALLRGVPVGPLIAAGILSLVLWN
What are the official names of this protein?
UPF0756 membrane protein ACIAD2383.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAAX_ECOLI
Sequence: MSKLDTFIQHAVNAVPVSGTSLISSLYGDSLSHRGGEIWLGSLAALLEGLGFGERFVRTALFRLNKEGWLDVSRIGRRSFYSLSDKGLRLTRRAESKIYRAEQPAWDGKWLLLLSEGLDKSTLADVKKQLIWQGFGALAPSLMASPSQKLADVQTLLHEAGVADNVICFEAQIPLALSRAALRARVEECWHLTEQNAMYETFIQSFRPLVPLLKEAADELTPERAFHIQLLLIHFYRRVVLKDPLLPEELLPAHWAGHTARQLCINIYQRVAPAALAFVSEKGETSVGELPAPGSLYFQRFGGLNIEQEALCQFIR
What is the function of this protein?
Negative regulator of the paaZ and paaABCDEFGHIJK catabolic operons.  Binds the consensus sequence 5'-WWTRTGATTCGYGWT-3'.  Binding of PaaX is specifically inhibited by phenylacetyl-coenzyme A (PA-CoA).
What are the official names of this protein?
Transcriptional repressor PaaX.
What is the protein family that this protein belongs to?
Belongs to the PaaX family.