Protein: LGRD_BREPA
Sequence: MNNIETYYPVTPLQQGLIFHSLLEPESGAYIVQMGLKLQGPLNIPLFEQAWQCLVDRHAIFRTRFVGGKVKEYVQVVLKDLKISLVEHDLIHLSSSEQEAFLHHFAKEDRKRGFDIEQAPLMRLNVFHLNSETVHFLWTLHHVLIDGWSMPLVFGEVFAAYEMLSKGQPLSLPPVRAYRDYIVWLKKQDLQQAEAFWRTYMQGFTEATPLSFGRAYKNPYLDQKQYRELDLTVSEQTSKALQTLARQHRLTVNTIVQGAWALLLNRYSGQDDIVFGATVSGRPADLPGVETMIGLFINTLPVRVQVNAEESVINWLKTLQQQQADFRQYEYTPLVEIQGWSDVPRGQSLFESILVFENMPVGKSGGGESAISIVDVYSEEQTNYPFTLVAASGKTIDIKVKFDESQFELAAIERVVDQLHSLLSSIAKNAKQRIGDLSLISESERQQVLVEWNQTAEDYPSGLCIHQAFEQQAEKTPDAVAVAYKNRELTYAQLNERANQLAHRLIRKGVKPDTLVGICLERSPEMIIGILGVMKAGAAYVPIDPAHPQERIAYMVADSQASALLTQQSLLEILPVTAAHVICLDSDLLADEPVDNASSEVTEQNLAYVIYTSGSTGLPKGVMIEHHSAINLAYALIDAFDIQPTSRVLQFTSFSFDVSVSEVVMALLAGATLVIEDRESLLPGPELIQVLQEQRITTVSMVSSVLAALPDADLPDLHTLIVGGEAPSRELVARYAPGRQFFNCYGPTEATVCSTMMLCQAGMNNPPIGRPIANATVYVLDANLNPVPVGVPGELYIGGKGLARGYWNRPELTAESFIPHPFGTAGERLYRTGDLVRYRQDGNLEFLGRIDHQVKIRGYRIELGEIENAIRQHPAVQEAVVIAREEKAGDKRLAAYLVAAGKAQPPAEEIALFLKETLPEYMVPAGVVWLDAIPLTVNGKVDRRALPVPDWGQLSTKREYVAPRTPTEEMVANIWSQVLSVERVGSFDDFFELGGHSLLATQTVSRLKEAFGVDLPLRVLFECSTVNKLSEWIAAAGEDKSGLSRIPLVPVSRDRHLPLSFAQQRLWFFDRLMPNSALYNIPTAVRLQGELDMDALEQSLQTIIQRHESLRTTFTDHNGEAVSVIHPEIDWKLERIDLRERSEEMRNEAGLRLAKEEANRPFDLVTGPLMRATIIQTDERDFIFLLNVHHIIADGWSAGILIRELFHCYQAFAKAEAPQLAELPIQYADYAYWQREWLTSDVLDEQLSYWRAKLGGAEPLLALPTDRPRPAVQSYAGSSISLLFDDELRANLLALSKREGTTLFMTLLAAFQVFLYRYTGQDDILVGTPEAGRSRQETEGLIGFFINTLVMRTDLSGEPSFKEVLARVRETALGAYAHQDLPFEKLVDELNVERSLSYSPLFQVMFVLQNIPVQADALDGIRILPLEGSQQVETTKFDLTLTMAEAANGLAATFEYNTALFERNTVERMIGHFSSLLKAVAANANQAITALPLMSEVEEQQLVLEWNDTAVAYSTEQLVHELVAQVARDMPDQPAVVTRDQLLTYGQLEAKANQLAHYLQKQGVGRGSLVGICVERSVEMVIGQLAIMKAGAAYIPMDPAYPKERLAFMMHDASMAIVLTQAKLRQKLPADTSRLICLDADWETIAQEPTAALVNTTAASDLAYVIYTSGSTGTPKGVEIEHAALLNLIFWHQRAYDVTATDRASQIAGTAFDASVWEIWPYVTKGATLYLPEEEIRLVPEKLRDWLVASNITVSFLPTPLTESMLALEWPGDTALRYMLTGGDKLHHYPSEKIPFTLVNQYGPTENTVVATAGIVPKEAGQTAAPTIGRPIDNVQVYILDAHRQPVPVGVSGELYIGGSSLARGYLNRPDLTQERFVAHPFTEKAGARLYRTGDLVRSLPDGSIEFIGRADDQTSIRGFRVELGEVETAIVALPAVKEAVVTVCTDKQGTKRLAAYLVLEEGAALATGDIRKALKETLPDYMVPAFFTQLAYLPLTPNGKVDRKNLPAPDFQRPELEGEFVSPSTEKERRLAAIWKDVLGIEQIGIHDNFFELGGDSILSIQIVSRANQAGLSLAPKQLFEYQTIAELAEIVEEKAAVQAEQGAVTGELPLLPIQKWFFRLPLANRDHWNQSVLLSIQAGIDPAALKQAVGQLMFQHDAFRMRYTQSESGWLQAMDAPSETIPFRVEDLSQLAPEEQSSAIEAIANETQTQLSLRAGQVVQTIYFHLGKEVPGRLLIVAHHLVVDGVSWRIILEDLQHAYQQIAAGQEVKLPAKTTSYKEWAQELERYAHSEAFKHEKSYWLSKSSVHSTELPADMPDSAENTEATVKSVHFSLTVEETKALLQQVPQAYRTQINDVLLAALAKALGQWTGKRSVFVNVEGHGREELAEHLDLSRTVGWFTSMYPVHLQWDETFSVRRALLTTKEELRAIPNKGLGYGVLRYLHAEQEIVDAISRIQADVLFNYMGKIDQIVGSDSLFGSAPESSGANLCPSAQRHHLLDVNSVVAGEQLHVTWRYSEKLQRESTIAAVAESFMAALREIVAHCTLPEAGGYSPSDFPLAVLEQKQIDKHIGFDRQIEDVYTLSPLQQGMLFHSLYNQDSGDYVVQFAVTFQNLDVSVLEKAWQNVLDRHSILRTHFVWEGLSEPHQVVRKDVKVTLTKEDWRHLQADVQDEMLAAFLEEDRRRSFDIAQAPLSRWVVFQTKDEEYRFVWSFHHVLLDGWSVPIVLNELLAHYAAISEGREGKLVPSQPFSQYIAWLKRQDREKAKPFWTDQLKGFHEPTSLGMGKNVAASQQKQYKEQSVLLSEEATEHLQSFTREHQLTLNTLVQGAWGWILGSYSGEEEVLFGATGSGRPADLPGVETMVGSFINTLPVRVPLQTDATLLAWLKDLQRRQLEIREYEYTPLFDIQGWSELPRGSALFESILVFENYPTVQAAKKGEDEAASATSGVSLEIHDVAAVEQTNYPLTLVAAPGKQVAFKLKYDQDRFDDAMIERVLNQMTRLMVYMSKSPELRLNDVALMDEDERKQVLIDWNRTEKEYPRELCLHHAFEQQAAKTPENIALEYKEQSLSYAGLNERANQLAHLLIAQGVKPDTTVAICVERSMEMIIGILGVLKAGAAYVPIDPAHPEERIAYMLDDSQAVVVLTQAGLADKFTQAAAPVICLGEKLFADRAHVDVDNIQTDVASTNLAYVIYTSGTTGLPKGVAVEHRSAMNMVQAYIAYFGLDESSRVLQFTSFSFDVSVSEIWQALLSGGTLVIEDRESLLPGPDLVRTLRERRISKVSMASSLLASLPVAEYPDLAVLEVGGDACSRELVARYATGRKFFNCYGPTEATVGTVIKQLTLDDDTPTIGRPFPNTKLYVLDQNRKPVPVGVPGELYIGGECLARGYWNRPELTAERFVANPFGQPGERLYRTGDLVRYLPDGNVDYLGRFDDQVKIRGYRIELGEIAEALRQHAAIREAVVLAREVRPGDKRLAAYLTSAAEQELSVDEIKQWLKEKLPDYMVPASYTWLPAIPLNVNGKVDRKALPAPDWGQITAAYVAPRNPLEEMIANVFAEVLAVEKVGIDDNFFELGGHSLLATQTVSRLREIVGVELQLRTLFEHPTVAGLGEQLELLTKQSSRKLAPPIGKVSRKEPLPLSFTQQRLWFLEQFTQNSSINNIPSFLRIQGELDVAAWEASFSAIILRHESLRTSFEVRDGRPVQVIQPHGDWAMTRIDLRALEPAEREAEIKRLAEQAIVQPFDLTKGLLLRASLVQLDANDFVFLFVMHHIASDGWSMGILLSELMTNYKAFRQGEASPLGELPIQYADFAVWQREWLSGEVLAEQLGYWREKLKGSEPLLQLPTDRPRPPVQTYEGEKMSVQFGAELLKQLQSLSRKEGATLFMTLFAAFQTLLYRYTNQDDILVGTPIAGRNKQETEQLIGYFINTLVLRTDMSGHPSFRELLARVRETALEAYAHQDVPFEKLLDELQLERSMSYSPLFQVMFILQNIPVQAEPAGDIQLSSFDLELGAVTSKFDMTVTMVETPDGLLATLEYNKALFDSSTITRMVEHFHKLMEEIVANPDQSITLLPLMREEEEQLLITEWNRTEVPYSREKCVHEMIEEMVSKAPDSIALIVGEQRVTYGELNRQANQLAHYLRKQGVGPEVLVGICAERTVEMMIGLLAILKAGGAYVPIDPAYPAERIAYIIGHSQIPVLLTQEHLLPTLPEHQAKVICLDRDWATVAVESEENPGKLATSDNLIYVIYTSGSTGNPKGVALEHRSVIYFLSWAHDTYTPEEMSGVLFSTSICFDLSVYEMFATLTMGGKVIMAENALQLPALPAADQVTLVNTVPSAATELVRMKGIPASVRVINLCGEPLSNRLAQELYAFPHVEKVFNLYGPTEDTVYSTHAIVTKGATNEPLIGRPQFNTHVFVLDSHRKPVPVGVPGELYLSGSGLARGYLHRPDLTAERFVQNPFREPGARMYRTGDLVRYLPDGNLQFVGRVDYQVKIRGYRIELGEIESVLNRFPGVKEVVLLAREDREGDKCLVAYIVFEADCTSKIHDLNHFLADKLPAYMIPQHYMILDSLPKTPNGKLDRKALPKPEYDRSEAGVEYVAPQTPVEIMLHAHWAAVLEMETIGVHDNFFEIGGHSLLATQLIFKVREELQLEVPLRILFETPTIAGMAKTIEEIIKHGLTSVSQEIDAKGLQDEVALDPAILAEQPYEGDPSQFQAALLTGATGFLGAFLLRDLLQMTDADIYCLVRASGEEEGLARLRKTLQLYELWDEAQAHRIIPVIGDLAQPRLGLSAGQFDALAATVDVIYHNGALVNFVYPYAALKKANVIGTEEIIRLAAAKKTKPVHFVSTIFTFASEEGEESVAVREEDMPENSRILTSGYTQSKWVAEHIVNLARQRGIPTAIYRCGRMTGDSETGACQKDDLMWRIAAGIIDLGKAPDMSGDLDMMPVDFASKGIVHLSMTEHSVNSNFHLLNPNATDYDDLIAAIENKGFELERVTMDEWIEAVQEDAKDKGMDANSAAPLGNLFSDGHSSRGSVVYVGNKTTRLLRQADIECPEIDEEVFAKVLDYFARTGQLRVTQNTRN
What is the function of this protein?
Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them.  This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid.  It also catalyzes the NAD(P)H-dependent reduction of the C-terminal glycine residue of the N-formylated 16-mer peptide, that binds to the peptidyl carrier domain of the terminal module of this protein, to form a peptidyl-aldehyde intermediate that is released from the enzyme complex.
What are the official names of this protein?
Linear gramicidin synthase subunit D.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.