PharMolix/UniProtQA huggingface dataset:
Protein: DAPH_BACC2
Sequence: MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTILDENNKHIVDYVVENDRRNSAIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: TRPE_YEAST
Sequence: MTASIKIQPDIDSLKQLQQQNDDSSINMYPVYAYLPSLDLTPHVAYLKLAQLNNPDRKESFLLESAKTNNELDRYSFIGISPRKTIKTGPTEGIETDPLEILEKEMSTFKVAENVPGLPKLSGGAIGYISYDCVRYFEPKTRRPLKDVLRLPEAYLMLCDTIIAFDNVFQRFQIIHNINTNETSLEEGYQAAAQIITDIVSKLTDDSSPIPYPEQPPIKLNQTFESNVGKEGYENHVSTLKKHIKKGDIIQGVPSQRVARPTSLHPFNIYRHLRTVNPSPYLFYIDCLDFQIIGASPELLCKSDSKNRVITHPIAGTVKRGATTEEDDALADQLRGSLKDRAEHVMLVDLARNDINRICDPLTTSVDKLLTIQKFSHVQHLVSQVSGVLRPEKTRFDAFRSIFPAGTVSGAPKVRAMELIAELEGERRGVYAGAVGHWSYDGKTMDNCIALRTMVYKDGIAYLQAGGGIVYDSDEYDEYVETMNKMMANHSTIVQAEELWADIVGSA
What are the official names of this protein?
Anthranilate synthase component 1, Anthranilate synthase component I.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: V19H_CATRO
Sequence: MELDECSPSIFIISFIFIAISIAILRRIRPKKTKALPPGPWKLPLIGNLHQFISRDSLPYKILRDLAQKHGPLMHLQLGEVSAVVASSPEMAKVITRTKDLEFADKPAIRAIRIVTYDYLDIAFNSYGKYWREMRKIFVQELLTPKRVRSFWSAREDVFSNLVKTINSANGKSINLTKLISSTTNSIINRVALGNVPYEREIFMELIKQLLTAAGGFKLVDLFPSYKIIHVLEGTERKLWKILGKIDKILDKVIDEHRENLLRTGKGSGENGQEDIVDILLKIEDGGELDHDIPFGNNNIKALLFDIISGGSDTSSTTIDWAMSEMMKNPQVMSKAQKEIREAFNGKKKIDENDVQNLKYLKSVIQETLRLHPPAAFLMRQCREECEIGGYHIPVGTKVFINIWAMGRDPEHWPNPESFIPERFENIPYDFTGSEHQLATFPFGSGRRICPGISFGLANVELSLALLLYHFNWQLPDSSTDLDMTEAIGIAARRKYDLHLIPTSYM
What is the function of this protein?
Component of the monoterpenoid indole alkaloids (MIAs, e. g.  echitovenine, tabersonine, lochnericine, 19-hydroxytabersonine and horhammericine) biosynthetic pathway; MIAs are used in cancer treatment and other medical applications (PubMed:31009114).  Cytochrome P450 catalyzing the hydroxylation of (+)-vincadifformine to (+)-minovincinine (PubMed:31009114).
What are the official names of this protein?
(+)-vincadifformine 19-hydroxylase, Cytochrome P450 V19H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: HEMA_I77A4
Sequence: MKTIIALSYIFCLVFAQDLPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKICDNPHRILDGINCTLIDALLGDPHCDGFQNEKWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINEGFNWTGVTQNGGSSACKRGPDNGFFSRLNWLYKSGSTYPVQNVTMPNNDNSDKLYIWGVHHPSTDKEQTDLYVQASGKVTVSTKRSQQTVIPNVGSRPWVRGLSSRVSIYWTIVKPGDILVINSNGNLIAPRGYYKMRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RS16_STAAE
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y190_HELPJ
Sequence: MKIFLVILSVFFFNGCFGLAYKTPISNPPISYDPYTTTIGSLYAKNLKENPKHSAAILLEDGFDALLHRVGLIRMSQKSIDMQTYIYKNDLSSQVIAKELLNAANRGVKVRILLDDNGLDSDFSDIMLLNFHKNIEVKIFNPYYIRNKGLRYFEMLADYERIKKRMHNKLFIVDNFAVIIGGRNIGDNYFDNDLDTNFLDLDALFFGGVASKAKESFENYWRFHRSIPVSLLRTHKRLKNNVKEIAKLHEKIPISAEDANEFEKKVNDFIERFQKYQYPIYYGNAIFLADLPAKIDTPLYSPIKIAFEKALKNAKDSVFIASSYFIPGKKIMKIFKNQISKGIELNILTNSLSSTDAIVVYGAWERYRNKLVRMGANVYEIRNDFFNRQIKGRFSTKHSLHGKTIVFDDALTLLGSFNIDPRSAYINTESAVLFDNPSFAKRVRLSLKDHAQQSWHLVLYRHRVIWEATEEGILIHEKNSPDTSFFLRLIKEWSKVLPEREL
What are the official names of this protein?
Uncharacterized protein jhp_0176.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PDRP1_ORYSI
Sequence: MSSSSSTSPRFGSMISAKLASPPPSLLLPPSPRLQGRRLTPPSCTPGTPAALPSPGPDKEPEREAAGSGSGSATTPRSPAQLGSSQLHRWSRARAHRSGRRLEWPTIRDRGSGGASSPPTPTRPHPSSDEAASAAAKVAVEEEDGYGVVGRDEAAKSIYMVSDGTGWTAEHSVNAALGQFEHCLVDRGCAVNTHLFNGIDDMDRLIEIVKQAAKEGALVLYTLADPSMAEATKKACELWGVPSNDILRPTIEAIASHIGVAPSGIPRSSPSRKGQLTEDYFRRIEAIDFTIKQDDGAQPQNLNRAHIVLVGVSRTGKTPLSIYLAQKGYKVANVPIVMGVNLPKSLFEIDQDKIFGLTINPVVLQAIRKARAKTLGFHGQKSNYAEMEHVRGELDHANQIFAQHPIWPVIEVTGKAIEETAAVVVRIFHDRKQKCAMPRISKRVAPIRIYDYLSEMVNTHVEYQKIFARDF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the dark/light-mediated regulation of PPDK by catalyzing its phosphorylation/dephosphorylation.  Dark/light-induced changes in stromal concentrations of the competing ADP and Pi substrates govern the direction of the reaction.  In the dark, phosphorylates the catalytic intermediate of PPDK (PPDK-HisP), inactivating it.  Light exposure induces the phosphorolysis reaction that reactivates PPDK (By similarity).
What are the official names of this protein?
Probable pyruvate, phosphate dikinase regulatory protein, chloroplastic, Bifunctional dikinase regulatory protein, BFRP, Pyruvate, Pi dikinase regulatory protein, PPDK RP, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GATA_LISW6
Sequence: MGLFDFSVKELHDKLVKKEITPFDLVTESFNRIESVEDKVGSFITLNKEAAFDVAEELGDAGIDPNNMLAGLPIGIKDNIVTKNLRTTAASKILENFDPIYDATVVSKLKNAQTINIGKLNMDEFAMGSSTETSYFHKTHNPWDLSRVPGGSSGGSASAVAAGEVLFSLGSDTGGSIRQPAAFCGVVGMKPTYGRVSRFGLIAFASSLDQIGPITKNVEDNAYLLEAISGLDANDSTSINQPVERFSDNLTGDIKGLRIGVPKEYLGEGVDPGVKQAVLDALKTLEKLGATWDEVSLPHSEYGVASYYILASSEASSNLSRFDGVRYGYRSPNAHTLEELYKKTRSEGFGDEVKRRIMLGTYALSSGYYDAYYKKAQQARTLIKQDFVNVFEKYDVIIGPSSPTTAFKIDGMINDPITMYSNDILTVPINLAGVPAISVPCGFSEGLPVGLQIIGNYFEESLLYKVAHAFEQETTFHKEKPNL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MAUD_PARDE
Sequence: MTSFLIASNILLWLAFLGVTVVMLGLMRQVGLLHERSSPMGAMITDHGPDIGDAAPEFELPDFFGRPVRIGGAEAQGRQTLLMFTAPSCPVCDKLFPIIKSIGRAEGINVVMISDGAPEEHRRFLDSHELGEMRYVVSAEAGMAFQVGKIPYGVLLDGQGIIRAKGLTNTREHLESLLEADRTGFASLQQYMASRKKQAA
What is the function of this protein?
May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
What are the official names of this protein?
Methylamine utilization protein MauD.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YICR_ECO57
Sequence: MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: Y2091_MYCTU
Sequence: MSGPQGSDPRQPWQPPGQGADHSSDPTVAAGYPWQQQPTQEATWQAPAYTPQYQQPADPAYPQQYPQPTPGYAQPEQFGAQPTQLGVPGQYGQYQQPGQYGQPGQYGQPGQYAPPGQYPGQYGPYGQSGQGSKRSVAVIGGVIAVMAVLFIGAVLILGFWAPGFFVTTKLDVIKAQAGVQQVLTDETTGYGAKNVKDVKCNNGSDPTVKKGATFECTVSIDGTSKRVTVTFQDNKGTYEVGRPQ
What are the official names of this protein?
Uncharacterized protein Rv2091c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RBM38_XENTR
Sequence: MHTVQKDTTFTKIFVGGLPYHTTDASLRKYFEVFGDIDEAVVITDRQTGKSRGYGFVTMSDRAAAERACKDPNPIIDGRKANVNLAYLGAKPRNLQSAFTIGVQQLHPAFIQRPFGLTPQYIYPPAIVQPSVVIPTPIPSLQSPYIDYNAATQAFTHYTTAAYEQYPYAASPATGYMGYGYTSAVQQPLSATTTTATTGAPPTAYIQYQPQQLQPDRMQ
What is the function of this protein?
RNA-binding protein that specifically bind the 3'-UTR of VegT transcripts, leading to maintain their stability and stimulate their translation, thereby playing a role in germ layer formation.  VegT is a localized maternal determinant essentially required for endoderm formation.  Also has some proneural function in the open neural plate and in the context of retinogenesis.  May also act as a mRNA splicing factor.  May play a role in myogenic differentiation (By similarity).
What are the official names of this protein?
RNA-binding protein 38, RNA-binding motif protein 38.
What is the protein family that this protein belongs to?
Belongs to the RBM38 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: LIPA_ACIC1
Sequence: MTAVTPDGRKLLRIEARNAQVPIERKPAWIRTRARMGPQYHALKELVRREGLHTVCEEAGCPNIFECWEDREATFLIGGDTCSRNCSFCQISSGRPQPLDRDEPRRVAESVARMGLRYATVTGVTRDDLDDEGAWLYAQTVREIHHAVPGCGVELLTPDFHGRPELLDEVFSARPEVFAHNIETVPRIFKSIRPGFRYERSLDVLRAAHDAGLVTKSNLILGLGETRQEIRAALADLRSAGCDLVTITQYLRPSIRHHPVVRWVEPAEFEELAAEARELGFAGVMSGPLVRSSYRAGRLYRAAIASRTDRRTDGATTQAPQTP
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD18_MOUSE
Sequence: MEFISSDYCTKDNDNEEESLLANVASLRHELKITEWSLHNLGEELSSVSPSENSEYVCSPSRSERLILEELTQPSHLGRLIYPPYKKVCKTSDSTDYQKKSRDQVSFSSVSMDQEVKNLREKLHKLRQQNACLVTQNHSLMTKIESVHFELTQSKAKIAMLESAQEQAANIPILEEQIINLEAEVSAQDKVLREAEDKLEQSQKMVIEKEHSLQEAKEECIKLKVDLLEQSKQGKRAERQRNEALYNAEELSKAFQLYKEKVAEKLEKVQDEEEILERNLSNCEKENKRLQEKCNLYKSELEILKEKFRELKEEHYSGKEKLMIMAMKNSEVMSQLTESRQCILKLERELEDKDEIVREKFSLLNENRELKVRVATQNERLELCQQDIDNSRVELKSLEKLITQIPLKREIVGFRSSLCKHQRSSVSDKEDKCIGCCEANKLMISELRIKLAIREAEIQKLHANLTVNQLSQNVANDSQECGKVNTLETEPVKLGGSQVESIKDGDQQTVNKQYEREKQRLATGIEELRAKLTQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNASKLENEMTKKCSQLLILEKQLEEKIIAYSSIAAKNAELEQELMEKNEKIRSLESNINTEHEKICFAFEKAKKIHLEQHKEMEKQIEQLETQLEKRDQQFKEQEKTMSILQQDILCKQHHLESLDRLLTESKVEMEKENMKKDEALKALQIHVSEETIKVRQLDSALEICKEELALHLNQLERNKEKFERQLKKKSEEVYCLQKELKIKTHNLEETSEQNAILQHTLQQQQQMLQQETMRNGELEDTQSKLEKQVSKQEQELQKQRESSTEKLRKMEEKYETAIREVDLKRQKIIELTGTARQAKLEMDQYKEELSKMEKEIIHLKRDGENKSMQLSQLDMVLDQTKTELEKTTNSVKELERLQHHTETELTETMQKREALENELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELIEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQVESLNEKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVIKEQEDYIATQYKEVIDLGQELRLTQEQMQNTHSELVEARRQEVQAQREIERLAGELEDIKQLSKEKEAHGNRLAEELGASQVREAHLEARMQAEIKKLSSEVDSLKEAYQIEMISHQENHAKWKLSAESQKTSVQQLNEQLEKAKQELEEAQDTVSNLHQQVQDRNEVIEAANEALLIKESELTRLQAKISGHEKTEDTKYLPAPFTTLTEIIPDSQHPNFAKHSQISLFKCRKLRRSISASDLSFKSHGNDDLSEELLQDLKKMQFEQTSAIESGHKDLPLTHSESFKPLPYNLEDDSSESNDFSTLSGMLRYINKEVRLLKKSSLQTATGLSQGGKL
What are the official names of this protein?
Coiled-coil domain-containing protein 18.
Protein: VSPH_BOTJA
Sequence: MVLIRVIANLLILQLSYAQKSSELVIGGDECNINEHPFLAFLYTGWIFCSGTLINKEWVLTVKQCNNRRPMRIYLGMHTRSVPNDDEEIRYPKEMFICPNKKKNDIMLIRLNRPVNNSEHIAPLSLPSNPPSVGSVCRIMGWGTITPSKATYPDVPHCANINLFNYTVCRGAHAGLPVTSRKLCAGVLEGGIDTCSADSGGPLICNGQLQGIVSWRGGSCAQPHKPGLYTKVFDYLPWIQSIIAGSTTATCPP
What is the function of this protein?
Snake venom serine protease homolog that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease homolog HS120, Venom serine proteinase-like HS120.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UCRI_RICTY
Sequence: MSDTEDNRNKQTTRRDFIVLTASSVAAVGAACAFWPIIDSLNPSTDVLALSSIEVDLSSIAIGQTVTVKWQGKPIFITNRTPDGIASARAVKMSELIDPEKDEVRVKAGHDNWLVTIGICTHLGCVPLSNQGEYNGWFCPCHGSQYDSSGRVRKGPASLNLVVPPYIFISDTKIRIG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ENO_LEPBJ
Sequence: MSHNSQIQKIQAREIIDSRGNPTVEVDVTLMDGSFGRAAVPSGASTGEYEAVELRDGDKQRYLGKGVLKAVEHVNVKIQEILKGQDALDQNRVDQLMLDADGTKNKGKLGANAILGTSLAVAKAAAFHSKLPLYRYIGGNFARELPVPMMNIINGGAHADNNVDFQEFMILPVGAKNFREGLRMGAEVFHSLKSVLKGKKLNTAVGDEGGFAPDLTSNVEAIEVILQAIEKAGYKPEKDVLLGLDAASSEFYDKSKKKYVLGAENNKEFSSAELVDYYANLVSKYPIITIEDGLDENDWEGWKLLSEKLGKKIQLVGDDLFVTNIEKLSKGITSGVGNSILIKVNQIGSLSETLASIEMAKKAKYTNVVSHRSGETEDVTISHIAVATNAGQIKTGSLSRTDRIAKYNELLRIEEELGKSAVYKGKETFYNL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: YQGF_XYLFM
Sequence: MPEASSPFPDGIVLGFDVGTRRIGVAVGSAWGAGARAVAVIDVHGVAVDWNALDRVKRNWLPVGLVVGDPLTLEGHDQPIRKQAHAFACQLRERYRLPVVLVDERSSSVEAASRFAGARAAGYKRRRDADTLDAIAAAVILERWLADPMQATSLP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_FRATM
Sequence: MSKLNAYFGEYGGQFVPQILVPALDQLEQEFIKAQADESFKQEFKELLQEYAGRPTALTKTRNIVKNTRTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLDLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVHSGSATLKDACNEALRDWSANYSKAHYLLGTAAGPHPFPTIVREFQRMIGEETKQQMLAKEGRLPDAVIACVGGGSNAIGMFADFIDEKNVKLIGVEPAGKGIETGEHGAPLKHGKTGIFFGMKAPLMQNSDGQIEESYSISAGLDFPSVGPQHAHLLAIGRAKYASATDDEALDAFKLLCKKEGIIPALESSHALAHALKLAYEDPNKEQLLVVNLSGRGDKDIFTVHDILKEKGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: NAGS_NEOFI
Sequence: MSPHTGWPRTVNSSLLKKHRSSLCTCQHTSSFLPRSFSTTADRHVQQSADFSSTSRSYDRLGRRAKEKLLDREFFLSLLSSASTKREAKSYLARLKAQYPKSPDENKPEPEKLATAPTLPSGVNLGSFYGASRSVYESPVFRQGPSPTAPPSLEPVERLHLALVRLSTPQSLDDNIIDGVAKTLSQLNRLGLTCCVVVDPGTEGVASTLRQVAIEQADRLAVAIQKQPDSKSLRLDSVFSIDASRPGLPQVSSRKALLNPLRHGHTVILTPIAYTEDVPRAIIVPANDAVLALTKELAGLASTPDPDEDPMVTAERIGRLQKEVSLDRVILLDSLGGIPAFNRRQTSHVFINMEQEYDDIENELLQAREMVPATETSLLKAGPSSIADNNPVSKFVNAEVVPVPSGPTQELKTAAPQRSAIEGHLENLRVAQKALTMLPAASSGIITSPFEVASSAQPSPTSEFSAVGTRRQRNPLIHNLLTDKPLLSSSLPMSRRGPTNNGQGTVYPVTSHTTFVKRGMPLTMLPNPWTEPWTPQSRPRLKLDDPSIDLPRLVHLIEDSFDRKLDVQDYLNRVNDRLAGLIIAGEYEGGAILTWELPPGVEDDGSEASNARMVPYLDKFAVLKRSQGAGGVADIVFNAMVRSCFPNGVCWRSRKNNPVNKWYFERSLGTWKLSDTNWTMFWTTPSLVEDSQKFRDYEAVCRSTQPSWADDTGVVD
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UNG1_BACFN
Sequence: MNVKIESSWQQRLQEEFDKPYFEKLVNFVKNEYGKAHILPPGHQIFHVFNSCPFQNVKVVILGQDPYPNPGQYYGICFSVPDGVAIPGSLSNIFKEIHQDLGKPLPNSGNLDRWVKQGVFPMNSVLTVRAHETGSHRNIGWETFTDAVIKKLSEERENLVFMLWGSYAKEKASLIDTDKHLILTAVHPSPRSADYGFFGCKHFSKANTFLRSRGIEEIDW
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase 1, UDG 1.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_RHOCS
Sequence: MADIWTDYGVPGAIIVAQILALMVPILVSVAFLVYAERKVLGLMQLRQGPNMVGPWGILQSFADALKMIGKETIIPAGANRIIFLAAPMLTMMLALAAWAVIPFGEGLVISDINVGILYLLAISSQGVYGIIMAGWASNSKYAFLGGLRSAAQMVSYEVSIGLVIITVLLCVGSLNLSDVVEAQKTVWFAIPLLPMFVIFFISALAETNRAPFDLPEGESELVGGFHTEYSGMAFGLFFLGEYANMILMSAMTSVLFLGGWLPPLDVAPLNWVPGPIWFILKICFCLFLFVWVRATVPRYRYDQLMRLGWKVFLPFSLVWVILTAGVLVTFDWLPK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOC_CHRSD
Sequence: MKDLVKVLKSQAQSEEFDAIKITLASPDMIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRMKHRGIICEKCGVEVTKAAVRRERMGHIELAAPVAHIWFLKSLPSRIGMFLDMTLRDIERVLYFESFMVIDPGMTTLERGQLLNDEQYFEALEEFGDDFDARMGAEAVQALLNDVDLDEEIERLREEIPQTNSETKIKKLSKRLKLLEAFQKSGNDPAWMIMEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLNAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYSKLQAGGQASTIKAAKKMVERELPEVWDILADVIREHPVLLNRAPTLHRLGIQAFEPLLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLESRTLMMATNNVLSPANGEPIIVPSQDVVLGLYYMTREKIGAPGEGMVFSNLDEVERAFGTQSVSLHARVKVRLTEYDRDEDGGEWTSSTKIHDTTVGRALLYRILPKGMPFELVDQPMKKKAISGLINAVYRRSGLKDTVIFADQLMYTGFRLATWSGASIGVNDFVIPDSKKEIVDGAEEEVKEIENQFSSGLVTAGEKYNKVIDIWSKANDKVAKAMMAGISKETAIDREGNEVEQDSFNSVFIMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVSQDLVITEEDCGTEDGLTLHPVIEGGDVIVSLAQRVLGRVVAQDVVDPATDDVLIARGTLLDEAWCARLDTMGVDEIVVRSAITCETAHGVCSACYGRDLARGHQVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRASAVDSVQVKHGGTVRLHNIKHVERSDGKLVVVSRSSALAVADEHGREREYYKLPYGAELSVRDGDMVEAGTPVAKWDPHTHPVVAEVEGKVQFSDMEEGLTIHRSVDEMTGLSNIEVIESASRPASGRDKRPMIMLLDENGGHVTLPGSNTPVQYMLPGKAIISVENGGQVGVGEVIARIPVEASGNKDITGGLPRVADLFEARKPKEPAILAEVTGTISFGKETKGKRRLTITPEEGDPLEMLIPKWRQIGVFEGETVEKGEVISDGPSNPHDILRLLGVAELAKYITAEIQDVYRLQGVVIDDKHIEVIVRQMLRKVEITDSGDSSFITGDQVEFVRVLEENQRLAQEDKFPAKYDRLLLGITKASLATESFISAASFQETTRVLTEAAVTGKRDYLRGLKENVVVGRLVPAGTGLAHHAERRRRREDPESTANPSAFDVEQELGAQLTALDAEDDDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: TYSY_RHILO
Sequence: MRQYLDLLQHVLDNGADRSDRTGTGTRSVFGYQMRFDLARGFPVTTTKKLHLKSIIHELLWFLAGDTNIKYLTDHGVTIWDEWADENGDLGPVYGRQWRSWPDGHGGSIDQIAGLLKEIRRNPQSRRLIVSAWNPAEVEAMALPPCHCLFQFYVSEGRLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVTGLKPGDFVHTLGDAHLYSNHFEQAREQLQRTPRALPTMWINPEVKDLFAFRFEDFRLENYVADASIQAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_CITK8
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRVTGTPLEALVRQKVPAKPVSCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQTIHHKYVPIAVKIAPDLSEDELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDETGGLSGRPLQLKSTEIIRRLSQELKEQLPIIGVGGIDSVIAAREKMAAGATLVQIYSGFIFKGPQLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.