PharMolix/UniProtQA huggingface dataset:
Protein: NUDC_SALDC
Sequence: MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: DNAK_HYDCU
Sequence: MGKIIGIDLGTTNSCVAVMEGKETKVIPNAEGARTTPSIVAYADDGEVLVGDSAKRQAVTNPENTLFAIKRLIGRRADDAVVEKDKDMVSYKIIAADNGDAWVQVGDKKLSPQEVSARTLMKMKKTAEDYLGHEVTEAVITVPAYFNDSQRQATKDAGKIAGLEVKRIINEPTAAALAYGMDKVKADSKIAVYDLGGGTFDISIIEVADLDGEKQVEVLSTNGDTFLGGEDFDNVIVDYIATEFKKDQNVDLKLDKLALQRVREAAEKAKIELSSREQTDINLPYVTADATGPKHLNMKITRAKFESLIEGLVQRSIDPCKTALKDAGLSASEIDDVILVGGSTRVPMVQAAVKEFFGKEPRKDVNPDEAVAMGAAIQGGVLSGDVNDVLLLDVTPLSLGIETMGGVMTKLIEKNTTIPTRKSQTFSTAEDNQSAVTIHVLQGEREVSSGNKSLGQFNLDEIPPAPRGTPQIEVTFDIDANGILNVSAKDKATNKEQHITIQASSGLSEDEIEAMVKDAEAHAAEDAKLKELVEARNQADAMVHGTKKLLDEQGEGVEAAEKEAIEKAIADLEEAIKGDDKAVIDEKTQALATASQKLAEKAYAQPGAEAGAEQQGSANNADDDIVDAEFEEVNDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HTPG_COLP3
Sequence: MSETNQVQNHAFASDNAKILQLMIHSLYSNKEIFLRELVSNAADAADKLRFKALSDNTLYENDGDLRVRVSCDKENNTLTISDNGIGMNVDEVIEHLGTIAKSGTAEFFSQLSGDQASDSQLIGQFGVGFYSAFIVADKVTVRTRKAGDSATDGVEWISAGEGEFTTAKIEKTNRGTDIILHLKEDESEYADDWRLKSIVTKYSDHISVSVEMLTAEVPAVEAVAEVTDEKDNVTRPAADAVDAIPALWEPVNKATALWTREKADITDEEYKEFYKHVSHDFGDPLLWEHNRVEGKTEYTSLLYVPTKAPFDMYNREKQHGLKLFVQRVFIMDDAEQFMPTYLRFVKGLLDSNDLPLNVSREILQDNKVTQAIRKGCTKRVLKMLEKLGNKDADKYQGFWDEFGQVLKEGPAEDHANKEQVAGLLRFASTHEDSTTQNVSLASYIERMKEGQDKIYFVVADSFEAAKNSPHLEVFRKKGIEVLLMSDRIDEWLVSHLTEFDGKQLQSVTRGGLDLGDMDDAETKEAQEKLEKEYDSVVKRIKASLDGKVKEVKLSQRLTDSPACIVADDDDMSSQMAKLMASVGQEVPDTLPIFEINGEHALVKHVADEQDDDMFNQWVEVLFEQAMLAERGSLKDPASFVSRLNKLMLSLTK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y019_BACMK
Sequence: MMRGGMGNMNNMMKQMQKMQKDMAKAQEELGEKTVEGTAGGGMVTVIASGHKQVLEVKIKEEVVDPEDIEMLQDLVLAATNDALKKVDELSNSTMGKFTKGMNLPGGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BcerKBAB4_0019.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PURA_ECOBW
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_SALAI
Sequence: MGALKPWHIAVLVVVLILLFGAKRLPDAARSLGRSLRIIKAETKSLHDDDRDLAEKANAQAGYQPLPPQVQQEPYPQQTPYQAPPQQQPVVDPVQRARDS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LITD_LATHE
Sequence: EPSGNSLSSALNELLDKNNNYAIPKVAIIFDDFKSSLTGGDDGLIDNVIEVLNTVKVSINSVTENNNWTPLHFAIYFKKNPAVSAVLILENKDIEARTSIMLIVQKLLLELYNYFINNYAETLDEEALFNRLDEQGKLELALIMHNK
What is the function of this protein?
Insecticidal presynaptic neurotoxin that induces massive neurotransmitter release at insect (but not vertebrate) neuromuscular junctions.  Native toxin forms cation-permeable pores (with high permeability to calcium) in lipid membranes locust muscle membrane and artificial lipid bilayers (By similarity).  May bind to insect neurexin-1 homolog, insect adhesion G protein-coupled receptor L1 homolog, and insect receptor-type tyrosine-protein phosphatase S homolog, and induces neurotransmitter exocytosis both by forming tetrameric pores in membranes and signaling via G protein-coupled receptor (By similarity).  Oligomerization is a process independent of divalent cations (By similarity).
What are the official names of this protein?
Delta-latroinsectotoxin-Lhe1a, Delta-LIT-Lhe1a, Delta-latroinsectotoxin, Delta-LIT.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 01 (latrotoxin) family. 04 (delta-latroinsectotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: TULP_DROME
Sequence: MSGINSRNQKMEQQRQLMEAYIRQKRASPGMVQASDLQINRPMSGMRSNSRELHAYDGPMQFISSPQNPDQILTNGSPGGINPVAMNTSRNHSNNMRSLSTINQEADLIEEISSHELEDEESSPVTVIEQHQQSASHSANSTQSQKPRARQHSFSDNLDEDDYTNRNVAGAAPVRPAGMASSPYKDATLDGSSNGTGNGTGGESEGDVIGNIDQFVMQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKIFLLGGRKRKKSKTSNYIVSCDPTDLSRNADGFCGKLRSNVFGTSFTVFDNGNKESTESPRLDLAVIIYDTNILGFKGPRNMTVILPGMTEDDQRVKISSADPKQQGILDLWKMKNMDNIVELHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPEYIVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIACE
What is the function of this protein?
Functions in regulating protein trafficking, retinal maintenance and lipid storage (PubMed:23228091, PubMed:23355467, PubMed:24068974, PubMed:26723017).  Protects photoreceptor cells R1 to R6 against light-induced retinal degeneration by stimulating norpA-mediated endocytosis of the rhodopsin ninaE (Rh1) (PubMed:23228091).  In the auditory receptor neurons, functions as a cilia trafficking regulator of various transient receptor potential (TRP) channel components including iav and nompC (PubMed:24068974, PubMed:26723017).  Likely to deliver pre-ciliary vesicles containing membrane proteins such as iav and nompC to the intraflagellar transport complex (IFT) at the cilia base (PubMed:24068974, PubMed:26723017).  Plays a role in the inhibition of fat storage (PubMed:23355467).
What are the official names of this protein?
Protein king tubby.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, cilium membrane; Peripheral membrane protein. Note=Detected in the cytoplasm and nucleus of the chordotonal neurons (PubMed:12204260, PubMed:24068974). PtdIns 4,5-P2 binds to and regulates its localization to the ciliary base (PubMed:26723017). In the dark, localizes mainly to the rhabdomere domain of photoreceptor cells R1 to R6 (PubMed:23228091). When dark- reared flies are moved into the light, the protein translocates to the cytoplasm (PubMed:23228091). Under normal conditions (12 hr light/12 hr dark), localized mainly in the nucleus of photoreceptor cells with minor staining in the cytoplasm (PubMed:23228091).
Protein: PSBI_EUGGR
Sequence: MLILKVFVYALILIFVSLFVFGLLSNDPGRNPYDDTGELMREVFYKDPYKGPL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: VE1_CRPVW
Sequence: MAEGTDPLDDCGGFLDTEADCLDCDNLEEDLTELFDADTVSSLLDDTDQVQGNSLELFQHHEATETLKSIEHLKRKYVDSPDKSLGIDNSVNAESLQVESGFGSQQSVSDTPVTDILNANTARVKHLLLFRQAHSVSFSELTRTFQSDKTMSWDWVGGLADIHASVLESLQTSLRSHC
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: HGPRT_STAEQ
Sequence: MHKDLKNVLLSEEDIQNICKEMGAIITEDYKDRPLVCVGILKGSVMFMADLIKRIDTHLSIDFMDVSSYHGGTESTGEVQILKDLGASIENKDVLIIEDILETGTTLKSITELLQSRKVNSLEIATLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYRELYRNLPYIGTLKAEVYSK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA2_SYNJB
Sequence: MTTVIQRRSTSNVWEQFCEWVTSTDNRLYIGWFGVLMIPTLLTATTCFIIAFIGAPPVDIDGIREPVSGSLLYGNNIISGAVVPSSAAIGLHFYPIWEAASLDEWLYNGGPYQLIVLHFLIGVFCYMGREWELSYRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHQLGVAGVFGGALFSAMHGSLVTSSLIRETSEEESQNLGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGISIMAFNLNGFNFNQSIVDSNGRVVGTWADVLNRANLGMEVMHERNAHNFPLDLAAVEVAPAVRG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 2, PSII D1 protein 2, Photosystem II Q(B) protein 2.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: HFQ_BURL3
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARPVNFHPDAEASS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RUVC_TRIV2
Sequence: MEKRILGLDPGLAILGFGAITCTPGLTQLQSTKVNILDFGVIKTSADIEIGQRLCTLFDDLHTVIDNLQPDVVAIEKLFFYRMSSTIVVAQARGVVMLALAQHHLPYVEFTPAQVKLALTGYGNADKSEVQEAVARELDLAEIPQPDDAADALAVALTAWYQM
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PDXS_DEIRA
Sequence: MRGQPRPKLRRMTEQQTGTPQLKQGFAEMFKGGVIMDVVTADQARIAEAAGATAVMALERVPADIRKDGGVARMSDPKMIREIMAAVSIPVMAKVRIGHVVEAQILQAIGVDFIDESEVLTPADEQFHILKRDFKVPFVCGAKNLGEALRRVGEGASMIRTKGEAGTGNVVEAVRHARAVLGDIRAVQSRPAEELMTVARDLQAPYDLVQYVHAHGQLPVVNFAAGGVATPADAALMMQLGLDGVFVGSGIFKSANPERRAQAIVRAVTHFQNPDILAEVSEDLGAPMTGINIDELIPEARLASRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: SYG_BIFLO
Sequence: MAQSKLDEVVSLAKRRGFVFPAGEIYGGTRSAWDYGPLGVALKDNIKREWWRSMVVTRPDVVGVDTSIILPPEVWVASGHVSVFNDPLVECLNCHKRNRADKLEESYAEKHGDKMPENGMKDIVCPNCGIRGQWTEPRDFNMMLRTHLGPVEDENSLHYLRPETAQGIFVDFKNVMTSSRSRPPFGIANMGKSFRNEITPGNFIFRTREFEQMEMEFFVTPGTDEEWHQYWIDARTRWYIDLGVKPENLRHYEHPKEKLSHYSKRTVDIEYKFGFQGSDWGELEGIANRTDYDLSAHSKHSGEDLSYFNQATGEKYVPYVIEPAAGLTRSLMCFLVDAYDVDEAPNTKGGVDKRTVLRLDPRLAPVKAAVLPLSKKPELQTVAQNLADDLRFNEWMIDYDESGAIGRRYRRQDEIGTPLCITVDFDTLEDHAVTIRERDTMAQERVALDKVADYVAARIGEKRTRVPLKPVEMGGEPWPESGVQEAGGLY
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_XYLFA
Sequence: MLKNDRLLRALQRDTVDRTPIWLMRQAGRYLPEYRAVRQHAGSFLKMAKTPELACEITLQPLHRFPLDAAILFSDILMIPDAMGLELHFIEGEGPRLGKPIRDAAAITQLAVPDMETELRYVMDAVRLIRKELDNSVPLIGFSGSPWTLACYMIEGGSSKEYAHIKAMAFNAPDVLHQLLNTVTNAVISYLAAQRAAGAQALQVFDTWGGILSPTMYRTFSLPYLTRIARELERGTGTERTPLVLFGKGNGPYIAELAMSGTEAVGVDWTIELEDAARRSNGQVALQGNLDPATLYGTPNNIAHEVQRTLDSYAAGNGGSREGHVFNLGHGMTPGMDPDHVSALVEAVQRLSRR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATB_ARCFU
Sequence: MKEYKTITQVAGPLVFVEKTEPVAYGELVTITLPDGSTRRGQVLDTSKDVVVVQVFEGTRGVDTSSTVRFTGDIVKLNCSQDMLGRILSGSGEPIDGGPKIVPEERRPIVGAAINPYARQYPREFIQTGISAIDGMNTLVRGQKLPIFSGSGLPHNDIALQIARQAKVRGEGEEFAVIFAAMGITYEEAYQFMKEFERTGALERAVVFLNLANDPAIERLLTPRMALTAAEFLAYEYDLHILVILTDMTNYCEALREISAAREEVPGRRGYPGYMYTDLATIYERAGRIRGRKGTITQMPILTMPGDDITHPIPDLTGYITEGQIVLSRELHAKGIYPPINVLPSLSRLMKEGIGEGYTREDHPQWNDQMYAAYAEGVDLRGLVAIVGEEALSERDRLFLKFADEFERRFVQQGRYEDRDIEYTLDLGWELLAMLPERELTKVERKFIEKYHPKYRKKEAKPEEATEEAS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CTAA_METEP
Sequence: MRLSTHPTLDRFDAVPAASYRPGHGAVRAWLYLLAVLVVAMVAVGGATRLTGSGLSITEWRPVTGVVPPLDAADWAVEFDKYRDTPQYRILNQGIGLDGFKTLYWWEWGHRLLGRIVGLVFFLPFAWFWARGMLGRRLLLGLLGLGLLGGLQGAIGWIMVASGLQPGMTAVAPLKLALHLTTASLILAGLVWLAAGTRPRALAPAPEPVRVVAGLLPALVLVQIWLGGLVAGSKAGLLYNTWPDMDGVLVPPARVLFDKVPFIENFIDNLALVQFNHRLFAYLVVVVAIAHAIQAARTASGSAAAGRAMGLAALATAQMGLGIATLLLHVPLWAGLAHQVFAMAVLIMATVHARLARGVPAATAPTGAEVPIGLEALAGRGA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAGZ_THISH
Sequence: MSLGPVMLDLEGTALTETERRLLTHPRAGGVILFTRNFESLGQLTELLREIHALRTPRLLVAVDHEGGRVQRFREGFTRLPAAARFGEQYDRNHARGRELARMAGWLMAAELRAVGVDFSFAPVLDLAHGVSGVIGDRAFHRNPEVVADLAHHYMSGMQHAGMAAVGKHFPGHGGVREDSHLALPVDRRTPADLYTDILPFERMVRFGLAGIMPAHVVYERCDPLPAGFSSYWLRGELRDRLGFEGVIFSDDLSMAGAECMGDYPDRARAALKAGCDMVLVCNHPEQAARVLDALDDEPDPVSIARLARMHGRKGMTWGELTDSDEWQKARAVINALDDSPLMELDV
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_PROM2
Sequence: MKDRIVRATAANGGIRLVAVLTTESSLEAKKRHGLSYLATCILGRAFSASLLLASSMKIMHGRVTLRVRSDGPLKGLLVDAGRDGKVRGYVGNPDLELDLVKIASNKYSFDFKNALGTGYLNVIRDSGIGEPFTSTVELVNGNIAEDLASYLYHSEQTPSAVFIGEKIENKGVICSGGLLAQVLPKKDTDPLLVSLLEERCKEINSFSEDLFQSKDNLLSLIRNIFPDIDDKSISEKARSQEVSFKCKCSKKRSLNAMKMLDKSELEDILKKDGEAELVCEFCKNKYLINYEEIKSIIEN
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBG1_YEAST
Sequence: MSTTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSGGGAGIGFDVARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVTVPGVIRYKGAKIQMLDLPGIIDGAKDGRGRGKQVIAVARTCNLLFIILDVNKPLHHKQIIEKELEGVGIRLNKTPPDILIKKKEKGGISITNTVPLTHLGNDEIRAVMSEYRINSAEIAFRCDATVDDLIDVLEASSRRYMPAIYVLNKIDSLSIEELELLYRIPNAVPISSGQDWNLDELLQVMWDRLNLVRIYTKPKGQIPDFTDPVVLRSDRCSVKDFCNQIHKSLVDDFRNALVYGSSVKHQPQYVGLSHILEDEDVVTILKK
What is the function of this protein?
Involved in ribosomal function.
What are the official names of this protein?
Ribosome-interacting GTPase 1, GTP-binding protein RBG1, Genetically interacts with ribosomal genes protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y677_MYCPN
Sequence: MQQIFFKDPILGEVLFDQQTKWMYELVETEAFRRLRNIKQLGINFHFYPGGVHTRYSHSLGVYELLRRILNTPAFAPIDENKKQTVLVAGLLHDIGHAPHSHAFEIYFAKAPNFKKELFIHEEVTTLFVNSEPIKSILKANQIDPKLVAALIDENKELKPSNYWMRQLISSDLDADRMDYLLRDSYFTGTSHSLIDYQTIIKEMDCVKVKGIYEIFFKDKCLPLIENFLITRHHMYQSIYSDGRSISTELNLWFVFQRIKDLVDKNQFDFNGYKTLEQVCLPLLKNEHFDKKMLPAFVKLDDYVFQSFFVNLYQTTKDKILKKLLDSYLNSLKFEIKFYETKEQRDLDFEKQASKYKDAKYFITKFNNQFKGFYEGWSSHKNELKIKTMQNKHTNLSEISMLVKRSNELFFENALYKWANVFYRL
What are the official names of this protein?
Uncharacterized protein MG461 homolog.
Protein: QUEA_NEIG1
Sequence: MDISDFDFTLPEHLIAQHPPEVRGSSRLLVALSDMPLQDRVFGDLPDYVEAGDVLVFNNTKVMKARLFGQKDSGGRIEALIERVLDNHTALAHIRSSKSPKPGMGLVFEGGIRAVMVGREGELFCLRFEGGQTVYELLEQNGHLPLPPYIERAADADDDSRYQTVYAKYQGAVAAPTAGLHFTEELLRRLKDKGAVTAEVTLHVGAGTFQPVRVDKIEEHKMHSEWFEVPSETVAAVEAAKARGNKAWAVGTTSMRALESAARATGYLKDGQGDTDIFITPGYRFNVVDRLVTNFHLPKSTLLMLVGAFSGMGHIRAVYRHAIEREYRFFSYGDAMVLGRNEGGGL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSUG_ECOLI
Sequence: MSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPFPQNAQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFVVAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTVVCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSASEIARAMVVKWQSGLNGGLVVANPIPEQFAMPEHTINAAIDQAVAEAEAQGVIGKESTPFLLARVAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLAG
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.