PharMolix/UniProtQA huggingface dataset:
Protein: IMP2_CAEEL
Sequence: MAEAATEIPPTASNVTVFTFEEQATSSLALYGMSILCIIIGSIRSAQYIRTNIDKKRLIEGSITMREARKFPISASLVLFGLYLFFKPAAERFLWVARVFQILRVPEEYVQKINSTIISYTANTTTTGPSEPFLLRLASRIPQERVPEAIQNAATYAYTNLPTIQKAECMQLLTFLICFEGVNAFASLLKPFVTAFLKKMPLVPSFLRFNAPYLFSLKKGNKEMEEGDIEDAKKKETEYLFKIDFDRYDIIALLMCSPILISHLLKRHWITNNIIGVSFSILGIERLHLASFKAGSLLLVGLFFYDIFWVFGTDVMTSVAKGIDAPILLQFPQDIYRNGIMEASKHSMLGLGDIVIPGIFIALLRRFDYRVVQTTAESKAPQGSLKGRYYFVVTVVAYMAGLFITMAVMHHFKAAQPALLYLVPCCLFVPLLLAVIRGELSALWNYDESRHVDNEENRKKVDSGKKNN
What is the function of this protein?
Acts as intramembrane protease (Probable).  In larvae, required for the complete shedding of the cuticle during molting, possibly by regulating cholesterol uptake via lrp-1 (PubMed:15469912).  Involved in embryonic and larval development (PubMed:15469912, PubMed:29137240).
What are the official names of this protein?
Intramembrane protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22B family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: UPPP2_BACC1
Sequence: MADWLIGIIMGAVEGLTEFLPVSSTGHMILTGHLLGFDDERAKVFEVVIQLGSILAVVVIFWKRLWSLVGIGKVTDGPSLNLLHIIIGMIPAGVLGVLFHSAIKEVLFGPGPVVISLVAGGILMIVAEKFSKPSTARTLDEITYKQAFTIGMFQCLALWPGFSRSGSTISGGLLARVSHTAAAEYTFILAVPMMVAASGLDLIKSWDILSAADIPLFATGFITAFVVAMLAIVSFLKLLSRVKLTPFAYYRFILAAVFYFFIM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS12_CHLPM
Sequence: MPTIQQLIRHGRSVKASKTASPALEKCPQKRGVCTRVYTTTPKKPNSALRKVARVRLSNKIEVTAYIPGEGHNLQEHSIVLIRGGRVKDLPGVRYHIVRGSLDTSGVADRRQSRSKYGAKQPKEGGAAKGKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ISPH_GLUOX
Sequence: MSEQTTFAPSRTDGVEAHKTLRVLLAGPRGFCAGVDRAIRVVEEALRRYGAPVYVRHEIVHNRTVVEGLEAKGAIFVEELDEVPEDGHVVFSAHGVPKAVPAEAQRRNLLYLDATCPLVSKVHREAERHFAGGGPDQRHILMIGHAGHPEVVGTMGQLPPGAVTLINDAEEARTIQPEDPTKLAFITQTTLSVDDTAEIVDILRSRFPLIEGPKREDICYATTNRQEAVKAIAPESDLVIVIGSPNSSNSQRLREVAERSGARRALLVPKLENLDWSVLEGVETLGISAGASAPESLVQEMVTALAGKYTLKIEERIVKEENINFRLPGPLAGEDD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RLMN_HELAH
Sequence: MKPSVYDFTLKELSQLLKPSFRAKQLYLWLYAKYKTSFKDMQNNFSKDFIASLEQEFVLRTIEITHVSHSVDGSKKYLFKSLKDNHTFEAVFLKMKDKKIDEETNAILEGEKYTVCVSCQIGCQVGCSFCFTQKGGFVRNLKASEIIQQALLIKEDNNLPIEKALNIVFMGMGEPLNNLDEVCKAIEIFNTGMQISPKRITISTSGVADKIPILAEKNLGVQLAISLHAVDDKTRSSLIPLNKKYNIECVLNEVKKWPLEQRKRVMFEYLLIKNLNDSLNCAKKLLKLLNGIKSKVNLILFNPHEGSKFERPSLESARMFADFLNSKGLLCTIRESKALDIEAACGQLREKKL
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIU_SALTY
Sequence: MEMDLNNRLTEDETLEQAYDIFLELAADNLDPADIILFNLQFEERGGAELFDPAEDWQEHIDFDLNPDFFAEVVIGLADTEDGEINDIFARVLLCREKDHKLCHILWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: PVK1_PYCSU
Sequence: GSPGLIPFGRS
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, PycSu-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RK16_DRIGR
Sequence: MLSPKRTRFRKQHRGRMKGISYRGNYICFGRYALQALEPAWITSRQIEAGRRAMTRYARRGGKIWVRIFPDKPVTVRPTETRMGSGKGSPEYWVSVVKPGRILYEMGGVSETVARAAIEIAACKMPIRTQFVIAG
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MESH1_DROME
Sequence: MATYPSAKFMECLQYAAFKHRQQRRKDPQETPYVNHVINVSTILSVEACITDEGVLMAALLHDVVEDTDASFEDVEKLFGPDVCGLVREVTDDKSLEKQERKRLQIENAAKSSCRAKLIKLADKLDNLRDLQVNTPTGWTQERRDQYFVWAKKVVDNLRGTNANLELKLDEIFRQRGLL
What is the function of this protein?
ppGpp hydrolyzing enzyme involved in starvation response.
What are the official names of this protein?
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, Metazoan SpoT homolog 1, Mesh1, Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase.
What is the protein family that this protein belongs to?
Belongs to the MESH1 family.
Protein: PFA4_KLULA
Sequence: MAIKLKNRWLGVAIPAFLVALIGYGSHYFILSNFLSWNEQIFYQTCQTMIWVSYYLAIYTNPGIPPKDFKPSAEEWHNYCKKCRVYKPERAHHCKTCNQCVLAMDHHCPWTLNCVGHSNFPHFMRFLFWVIFSTAYLLFLLIGRIYLLWSIRHTAFHHRSTSEIIFICIMTPMDAFVLLTVSSLLGRCIYNQCLHGMTQIESWEMDRIQSLHYKNRLLAQVIDRLVERRPEILPAKQHEINKLLSKRYVNQEDFTNFPYDVNPWTNINNAMGPWYLWLWPWSKPPTIGTSFAKNELFFYDPNSSIEDMLMSLPWPPDGLTHHSRALGSGSSIETIVSGGEQVIRDKSVDLRDRLGRNSWYNDWGEDLSDFGVDTELE
What is the function of this protein?
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
What are the official names of this protein?
Palmitoyltransferase PFA4, Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TATB_CHESB
Sequence: MLDLGWSEILVIAVVLIVVVGPKDLPRVLRSFGRTTAKMRAMAGDFRRQFDEALREAELDDMKGLVDDVRKLDPRSEIRKHLSPLEEAGKEIRSGLSEAAKAKPAASSLPAADSKPAEPLKNGATSLGPEAPPPVTGETAAPKVSEKAEVGAVAASPGTSAKQAAPKAKAAAAAKAPTKNTASAPAKKPSPRRKKTAGTAP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CSKMT_DANRE
Sequence: MLLNRFLVPLRSLQKLTQARRWHQTSLINDLVVNMDKKAMWDRFYTENGSKGQFKNFEWFFGFPSVKDLVLPALQAMSCSHSGPLHILDMGCGTSALGPCIYSTSPCAVRVTCADISPVAVKLMEEHTKSTSTQPCNPSSALVFLELDCTQMTGHFKSRSLDLILDKGTTDALVRSKEGQVKAGQILRQSLQVLRPSGSFLQFSDEDPDARLIWLEREVQGAEVTADVGVQEIGELRGVSYFCYQISPRSRPHS
What is the function of this protein?
Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria.  Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methyl group per binding event.
What are the official names of this protein?
Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial, CS-KMT, Methyltransferase-like protein 12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UHPA_SHIFL
Sequence: MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW
What is the function of this protein?
Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT.  Activates the transcription of the uhpT gene.  Acts by binding specifically to the uhpT promoter region.
What are the official names of this protein?
Transcriptional regulatory protein UhpA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHSC_SALTI
Sequence: MIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFIAVGILLWLLGTSLSSPEGFQQAADIMDGFIVKFIMWGILTALAYHVIVGIRHMLMDFGYLEETFEAGQRSAKISFVITVVLSLLAGVLVW
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase cytochrome b556 subunit, Cytochrome b-556.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b560 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BPT_LEPIC
Sequence: MIQNKLQNFVDTLPISPEKSCSYYPERLSQIQYFPFPEEISKEVLQFFFDSGFRRNGNILYRTSCCGCKDCLSYRIPLDQFVPSRNRKKLLKKNSDLKICFESPNLTLEKEILYLRYQRSRYQNFVIEESDQELLEGMRWNLFEYKENSLEMTLSLDGKILCFMILDFASDSLSAVYSVYDPDYPDRSLGSFAILSSILYAKELGMKYFHLGYFLPGHPNMDYKKYWTPAQIREPVSNENRWIETDDFQKRYSDFSW
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BL1S2_MACFA
Sequence: MAAAAEGVLATRRDESARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLEAKYKKLEKR
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes.  In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.  The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension.  As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.  May play a role in cell proliferation.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 2, BLOC-1 subunit 2.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Lysosome membrane. Note=Localizes to the centrosomes in a microtubule-dependent manner.
Protein: DDHD1_HUMAN
Sequence: MNYPGRGSPRSPEHNGRGGGGGAWELGSDARPAFGGGVCCFEHLPGGDPDDGDVPLALLRGEPGLHLAPGTDDHNHHLALDPCLSDENYDFSSAESGSSLRYYSEGESGGGGSSLSLHPPQQPPLVPTNSGGGGATGGSPGERKRTRLGGPAARHRYEVVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDEDRACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSTTQSSETSKDSMEDEKKPVASPSATTVGTQTLPHSSSGFLDSAYFRLQESFFNLPQLLFPENVMQNKDNALVELDHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFMYKHEHDDDAKPNLDPI
What is the function of this protein?
Phospholipase A1 (PLA1) that hydrolyzes ester bonds at the sn-1 position of glycerophospholipids producing a free fatty acid and a lysophospholipid (PubMed:20359546, PubMed:22922100).  Prefers phosphatidate (1,2-diacyl-sn-glycero-3-phosphate, PA) as substrate in vitro, but can efficiently hydrolyze phosphatidylinositol (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol), PI), as well as a range of other glycerophospholipid substrates such as phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE), phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) and phosphatidylglycerol (1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol), PG) (PubMed:20359546) (By similarity).  Involved in the regulation of the endogenous content of polyunsaturated PI and PS lipids in the nervous system.  Changes in these lipids extend to downstream metabolic products like PI phosphates PIP and PIP2, which play fundamental roles in cell biology (By similarity).  Regulates mitochondrial morphology (PubMed:24599962).  These dynamic changes may be due to PA hydrolysis at the mitochondrial surface (PubMed:24599962).  May play a regulatory role in spermatogenesis or sperm function (PubMed:24599962).
What are the official names of this protein?
Phospholipase DDHD1, DDHD domain-containing protein 1, Phosphatidic acid-preferring phospholipase A1 homolog, PA-PLA1, Phospholipid sn-1 acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the PA-PLA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_PHYMT
Sequence: MAYSKLRRNTSQRKSLLRSLVSDLIIKEKIITTESKAKELQKKVEKVITLAKKKSLHHRRQVFKKLFDENINKEQTVTQKLFTTTAEKYMKRNGGYTRIIKTVPRRGDAAPMAIITFV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DEOC_SHESA
Sequence: MTDLKKAAQRAIELMDLTTLNDDDTDQKVIDLCHKAVTPAGNTAAICIYPRFIPIARKTLDELGAEDIQIATVTNFPHGNDDIAIAVLETRAAVAYGADEVDVVFPYRALMEGNESVGYELVKACKEACGDVLLKVIIESGVLADPALIRRASELSIDAGADFIKTSTGKVPVNATLEAAEIMLTVISEKNTKVGFKPAGGVRDAAQAAEFLGVAERILGADWVSPRTFRFGASSLLNSLLHTLELADAPKPTQGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FZD2_CHICK
Sequence: PDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSLELKFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCENFPRHGAEQICVGQNHSEDGGSSAALLTSAAPPAAHGTPGAPRYATPDRPFHCPRALKVPGYLNYKFLGEKDCAAPCEPSRPDGHMFFNEDEIRFARVWILVWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLEERVVCNERFQEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNGIDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHGGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFRQHWERSWISQHCKSLAIPCPLHFTPRMTPDFTVYMIKYLMTLIVGITSGFWIFSGKTLHSWRKFYTRLTNSRQGETTV
What is the function of this protein?
Receptor for Wnt proteins.  Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity).  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
What are the official names of this protein?
Frizzled-2, Fz-2, cFz-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RECO_NEIMB
Sequence: MSEYRVNHEPVFMLASSPWRESSLWVEAFSRRYGRVALLARSARKRQSELRGVLVPFVPVSVSWYGSQELKTLHRAEWVGGWRQPQGRALFGGLYVNELVLKLTAREDPVPELYDALAEVMEAVCCKAAYIDDLRRFEWRLLNLLGVAPDLNRDGDGGTIAAGGTYLVRPETAVFPVGKGFAVPPHAAGVVAPGQSLIDLREGSFRTAESLQQALKITRLFIRHLLPEGLKSRQVLEQIRQFDRKETARETVPTSDGTASNAV
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.  Involved in pilin antigenic variation (By similarity).
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SYAC_BOMMO
Sequence: MDTSMTGNEIRKTFIDFFIKKGHKYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGSVDPNSDMAQYIRVVNTQKCIRAGGKHNDLDDVGKDVYHHTFFEMMGNWSFGDYFKKEICAWAWELLTDVFKLSRERLYVTYFEGDPSSGLEPDLECRNIWLNLGVPEAHILPGSMKDNFWEMGETGPCGPCSELHYDRIGDREAAHLVNMDDPDVLEIWNLVFIQFNRETDGSLKLLPTKHIDCGLGLERLVSVIQNKRANYDTDFFMPIFKAIENATGVRPYSGKVGVDDVDGIDMAYRVLADHARTLTIALSDGGCPDNTGRGYVLRRILRRAVRYASEKLNAKPGFFGSLVYTVVELLGDVFPEIKKDPDSIVHVINEEEVQFLKTLLRGRNLLYRTIEKLNNSKTLPGDVAWRLYDTYGFPIDLTQLMCEEKGLNVDMEGYEKSRKESQLVSQGKAAGQEDLIALDVHAISHLQDTGIPATDDSPKYNYLPSSTDKDALYTFAPCTAKIVALRKNKEFVSEISSGQECGVILDRTSFYAEQGGQIFDEGYMVKIDDETVEFTVKNVQVKGGYVLHAGKVEGILKVGDTLSLHIDTERRRLVMNNHTGTHVLNNVLRKVLGNDSDQRGSLVMPDRLRFDFTNKGPMTIKQIKDTENEIKEIIAKNKTVYANYTSLSEAKKINGLRAMFDEHYPDPVRVVSVGVPVEDLIKNPDAPTGFETSVEFCGGSHLHRTSHIGEYVIVSEEGIAKGIRRIVAVTGPEAIKAINKLSVLENEVNNVANFIKEQNESISHKEVSKKIVDLTNEISQAQISYWKKDELRNMLKNLKKQLDDKERAEKAIIITQVTEKAKELCLERKESKYIVSELKAFGNTKALDGALKQVKQFCPNSAAMFFSVDKDADKIYCLAAVPKSDVEKGLLASEWVQSVVDIIGGKGGGKAESAQASGNNPNSLNEAIQIANEYAKSKLN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, cytoplasmic, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATA2_BPSP
Sequence: MPTLPRGLRFGSNGEVLNDFEALWFPERHTVDLSNGTCKLTGYITNLPGYSDIFPNKGVTAARTPYRSTVPVNHLGYRPVTTVEYIPDGTYVRLDGHVKFEGDLVNGSVDLTNFVISLAAQGGFDYQSVIGPRFSARFSAFSTKYGVLLGEGRETLKYLLLVVRRMREGYRAVRRGDLKRLRNVISTFEPSTIKGKRARAEFSQTYRDKLTGNKVEVRPSEGKWNSSSASDLWLEFRYGLMPLFYDIQSVMEDFMRVHKKIAKIQRFSAGHGKLETVSSRFYPDVHFSLEVTAVLQRRHRWGVIYQDTGSFATFNNGRLVPVKDWKTAAFALLNPAEVAWEVTPYSFVVDWFVNVGDMLEQMGQLYRHVDVVDGFDRKDIKLKSVSVRVLTNDVAHVASFQLRQAKLLHSYYSRVHTVAFPQISPQLDTEIRSVKHVIDSIALLTQRVKR
What is the function of this protein?
Induces host cell lysis.  Inhibits host MurA activity thereby blocking the synthesis of murein precursors necessary for the host cell wall biosynthesis.  May be responsible for the attachment to the host pilus.
What are the official names of this protein?
Maturation protein A2, MP, A2, Assembly protein, A protein.
What is the protein family that this protein belongs to?
Belongs to the Levivirus maturation protein family.
What are the subcellular locations of this protein?
Virion. Note=A single copy of the maturation protein is present in the virion.
Protein: YB1C_SCHPO
Sequence: MVKSYTRYEPTEFFGVIASSGCNILGQPSSSAKSVGRAIVGGLESVLEWDLKTGQLLSKWKDSDCSAKVTCIANFDEMYAVGYADGSIRLWKDGELLITLNGHKSAVTTMDFDKMGTRLASGSMDTDIIVWDIVAETGLFRLRGHKDQITKLLFITPPSKNTAEETVVDTDIDSGDMDVDSKSSDSFLLSVGKDSFMKLWDLSIQHCVETHVDHQGEIWAMCVSPDAKRCLTAGTGSDVKVWEISFPDDNNFTPTTKAFQQLGTFTRQSRDRPITLAYDVSNRYVVFQAHDRLLEVFRLRSSAELEKILNRRRRRKKSEDVSITLKDEYEPFALIRTTARASSVAWIPGNRTPTLVTSLQNNSIEVYALDVKSEGSAAPLTERASRISAIEIPGHRADVRTLALSANHDVILSGANGSLKLWNKKTTSCIRTIECGYVLAASFINNDKCIVSAYKSGELEVYDIASSSLIERIQAHDGAIWDLAVGHDGTYFATASADHTVKLWSLKSSFDFVPGTTRKVTTLKLEQTRQIDFTDDVLAVKISPDGRFVAASLLDNTVKVYYLDSLKFFLNLYGHKLPVLSMDISYDSKLLVTCSADKNVKIWGLDFGDCHKSIFAHQDSIMEVTFQPDTYNFFTCSKDREVRYWDGKSFDLILKLRGHHSEVWALAVGPTFVVSGSHDHSIRLWEQGDDLVFLEEERERELEEQYESTLVSSYENAEADGEVKDGDVAAVTKQTIESLKDGEKILEAITIGIEDLDQEIQYRLDLLKSPGKARGPRNPILAHLGVSAEEYVLNTFKKIRSSHLDDALLVLPFEHVLSLFRFIDIWASRKWSIPLVSRIIFFLLRTYHRQLTTTVKMRPLLNNIRSSLRGSLQEERSLIGYNAAGLSYLRHEWELTHNTSLEDIDSTSLEVDGKKRAFSNIV
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C3D6.12.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR3/UTP12 family.
Protein: RL3_YERPP
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKSLENDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLPEGQEFTAGQEISVEIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGHMGDERVTVQSLDVVRVDAERNLLLVKGAVPGATGGNLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SPEH_CLOB1
Sequence: MKYSGYHLVIDLFGCNFDQLENTEYIIEMLKKLARALDTKIVAKAFHKFHPQGFSGALIISESHITIHTWPEDAYIGIDIFTCSKCFDPRKIVAYLKENLIFKKVEIKEILRGKID
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: PHAT_AMAPL
Sequence: MSDINATRLPAWLVDCPCVGDDINRLLTRGEK
What is the function of this protein?
Major toxin that belongs to the bicyclic heptapeptides called phallotoxins (PubMed:24613547).  Although structurally related to amatoxins, phallotoxins have a different mode of action, which is the stabilization of F-actin (PubMed:24613547).  Phallotoxins are poisonous when administered parenterally, but not orally because of poor absorption (PubMed:24613547).
What are the official names of this protein?
Phallacidin proprotein.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.