PharMolix/UniProtQA huggingface dataset:
Protein: RAPA_KLEP7
Sequence: MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESIDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAAIESNRQQVMDALAQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: KITH_STRA5
Sequence: MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDEFGVVSSRIGMRREAVPISDDMDIFSYIQNLPQKPYCVLIDECQFLSKKNVYDLARVVDDLDVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKPVYEGDQIQIGGNETYIPVCRKHYFNPDI
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALU_RAT
Sequence: MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFGQLTPEESKEKLGMIVDKIDTDKDGFVTEGELKSRIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEYRNVTYGTYLDDPDPDDGFNYKPIMVRDERRFKMADQDGDLIATKEEFTAFLHPEEYDYMKDIVLQETMEDIDQNADGFIDLEEYIGDMYSHDGNADEPQWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQDKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
What is the function of this protein?
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues.  Seems to inhibit gamma-carboxylase GGCX.  Binds 7 calcium ions with a low affinity (By similarity).
What are the official names of this protein?
Calumenin, CBP-50, Crocalbin.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen.
Protein: RODZ_SERP5
Sequence: MNTEASQDKTVSMTTGERLRQAREQLGLSQQAVAERLCLKMSTVRDIEEDNLSADLASTFVRGYIRSYAKLVRLPEDELLPMLAKQAPLKVAKVAPMQSFSLGKRRKKRDGWLMSFTWLIVFVVVGLTGAWWWQNHKAQQEEIVTMADQSSAQLSQNNEGQSVPLTDSNADNSAPLADNGSTPVDTGVAPQQSQTPAVSGSATAQQPAVVSPSQTTLPETTPAAPTAPLPTADAGVTAPAVDPNALVMEFSADCWLQVSDANGKTLYSGSQKSGGKLSLAGTAPYKLTIGAPAAVQIQYQGKPVDLSRFVKSNRVARLTVAAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: SYS_BURVG
Sequence: MLDIQLLRKDLDGVAKRLADRGYTLDVAAFSALEAERRAIQTRTEELQARRNSLSKQIGAMKGKGEDTSAVMAEVGGIGDEMKASEVKLGEIQSRLSDLMLGMPNIAHESVPVGKDEADNVELRRWGTPRQFDFDVKDHVDVGTPLGLDFETGAKLAGARFTMLRGPIARLHRALAQFMLDTHTQLHGYSETYTPYIVNPEILYGTGQLPKFADDMFRVEKGGAENTITQYLISTSEISLTNTVRESIVDASALPIKLTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQVVAPDTSYAALDEMVGHAEAILQKLGLPYRVITLCTGDMGFSAAKTFDLEVWLPAQNTYREISSCSNTEAFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVAVLENYQNADGSVTVPEVLRPYMGGMERIDAPVQAS
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMF_ECO45
Sequence: MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_DESVH
Sequence: MLHIKTIEGQLDAKGLKFAIVATRFNDFIVDRLIGGACDYLQRHGCDRENLTIVRIPGAFEMPLVAKKLAHSGKYDGIIALGAVIRGATPHFDFVSNEASKGLAQACLESGVPLGFGLLTTDNIEQAIERAGSKAGNKGAEAAAAVLETVRVMEQL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TRMD_RHOPT
Sequence: MTWRATVLTLFPEMFPGPLGVSLAGRALASGLWGLEARDIRDSATDRHRSVDDTPAGGGPGMVLRADVLAAAIDAVDAAADRPRLVMSPRGRPLTQARVAELAAGPGPLIVCGRFEGIDQRVIDARGLEEVSIGDYVLSGGEIAAMALIDACVRLLPGVMGKLESSTDESFSAGLLEYPQYTRPQTFEGRAIPEVLLSGDHGKVAAWRLGEAEALTKARRPDLWAARPAQTIRAKGESQKTPKNKTDG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNAS1_CHINI
Sequence: MGLEKSLILLPLLVLVFGWVQSSLGKETSAQKFERHDMDSTGSSSSATYCNQMMKRRNMTQGYCKPVNTFVHEPQTAVHAVCSQKNVTCKNGNSNCYKSHSALHITDCRLKGNSKYPNCDYQTNQLQKHIIIACEGNPFVPVHFDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_FRATT
Sequence: MSKEKALESALSQIEKQFGKGAIMRLGDQEAAHDIDVIPSGIIALDVALGIGGYPKGRIIEIYGHESSGKTTLTLLAIAQCQKQGGTAAFVDAEHALDPKYAKLLGVDVDNLIVSQPDTGEQALEIADMLVRSGGVDIVVIDSVAALTPKAEIEGDMGDSHMGLQARLMSQALRKLTANIKRSNTLVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLEVKKGGSIKDGIDVSGNEIKVKVVKNKVAPPFKQADFELIYGEGISLEAELIDLGAKYNIIEKSGAWYSYKGKKIGQGKEKSKEYLKENTAERDEIERAILELLLPNKYSNKDSNDSPKEGSKIKTKVNPAVTQDELI
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_COCP7
Sequence: MAVCAGRLKCFGNPAVSLRTAASRAYATTTSPDPAIPSSSSASSSSALPKRPQTSFRDKLNAGPSFSDFLSGGNRDDARILDPNEAYALKTALVGPKGKKKEITRLPSWLKTSIPDSNNYKRIKNDLRGLGLHTVCEEARCPNISECWGGSSKSAATATIMLMGDTCTRACRFCSVKTSKTPPPLDPHEPENTAEALSRWGLGYVVLTTVDRDDLIDGGARHFAETVIRIKQKAPNILVECLTGDYAGDLEMVALMAKSGLDVYAHNVETVEALTPHVRDRRANFQTSLRVLKAAKAAVPSLITKTSMMLGLGETEEQMWDALRQLRAANVDVVTFGQYMRPTKRHMPVHEYVRPDVFELWKDRALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRRAESTGPESTNVPNVTPDAIVR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LEU3_XANC8
Sequence: MSKQILILPGDGIGPEIMAEAVKVLTRIDTQHTLGVTLVYDELGGAAYDKYGSPLADETLERARAADAVLLGAVGGPQWDTIDPALRPERGLLKIRSQLGLFANLRPALLYPQLADASTLKPEVVSGLDLLILRELTGGIYFGQPRGTRTLDNGERQAYDTLPYSESEIRRIAKAGFEMARLRGKKLCSVDKANVLASSQLWRAVVEEVAKDYPDIALSHMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDQASMLTGSIGMLPSASLDANSKGMYEPCHGSAPDIAGQGIANPLATILSVAMMLRYTFAQAAAADAIEAAVGKVLDQGLRTADIWSEGTTKVGTAAMGDAVVAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHDAG_HDVNA
Sequence: MSRSESKKNRGGREEVLEQWVAGRRKQEELERDLRKTKKKIKKLEEENPWLGNIKGILGKKDKDGEGAPPAKRARTDRMEVDSGPRKRPLRGGFTDKERQDHRRRKALENKKKQLGAGGKNLSREEEEELRRLTEEDERRERRVAGPPPGGVNPLEGGSRGAPGGGFVPNMQGVPESPFTRTGEGLDVRGDRGFPWDILFPSDPPFSPQSCRPQ
What is the function of this protein?
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding.  Packages the HDV ribonucleoprotein in hepatitis B virus empty particles.  Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg.  May inhibit viral RNA replication (By similarity).
What are the official names of this protein?
Large delta antigen, L-HDAg, p27.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=isoprenylated in the cytoplasm, and translocates in the nucleus possibly after phosphorylation. Translocates after to nuclear speckle, then to the ER membrane where interaction with Hepatitis B virus antigene takes place (By similarity).
Protein: ACDH1_AZOVD
Sequence: MDRTSSRCKVAIIGSGNIGTDLMIKVLRHGRHLEMGAMVGIDPASDGLARAKRLGVATTAQGVEGLLALPEFKDIGIAFDATSAGAHARHNELLQAHGVKVIDLTPAAIGPYVVPAINLDAELDAPNINMVTCGGQATIPMVAAVSRVAQVHYAEIVASIASKSAGPGTRANIDEFTETTSKAIEVIGGARKGKAIIVLNPAEPPLIMRDSVFVLSEVVDRDAIAASVKEMVASVQRYVPGYRLKQEVQFELIEKPANVPGVGLVSGLKTSIFLEVEGAAHYLPAYAGNLDIMTSAALSCAERLAERGKVRTLPSALV
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: Y053_METJA
Sequence: MGLSFNGENMIIFGLFGKTGCGKTEILNELKKHHPVIDIEEIARTRGSILGDLYHLSMRSQEEFDYLINKEIEKAKKFGYAVVEYEGRKIGGEKKLKIPELLADIKNYTYKILIDCPYECQINRLVSIYKPKNEKEKEILINKFLILKESFKKPEMIEAVDNIIELIKQDKYYEAAKLIEEKLYREHYMRNVKKIKPDLIVYNEDVKKSAKIIDEFIKKKLKEHNLI
What are the official names of this protein?
Uncharacterized protein MJ0053.
Protein: RK16_COFAR
Sequence: MLSPKRTRFRKQHRGRMKGISYRGNRICFGKFALQALEPAWITSRQIEAGRRAMTRNVRRGGKIWVRIFPDKPITARPAETRMGSGKGSPEYWVAVVKPGRILYEMGGVTEHIARRAISIAASKMPIRTQFIISR
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SSRP_SALPB
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAWLFGANFTPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKEREWQLDKARIMKNAGR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HMDH_CYBJA
Sequence: MFYHGASANQHWIAVDDLSKVPVDVDHYNVVPFQFRRAGEYKEPVLSGIVELDEVKFVVSQSDAAEQWQQLTAEDGTVWRSRAYHGKLGKYSDMAVGAFNKVLNLVRGAETFDIALVTCAYIAMFYTLFNLFARMRAVGSKVWLGLSTLVSSFFAFLFALYITTRVLDLSIPFLSLSEGIPFFVAVVGFNNKILLAEKVLQNQLNAQSSKNDAPTVLYQALREQGPLLLRDHLFMITAFLGCSFYASYLDGLKNFCILAALILAFDILTTSTFLSAILSLKLEINQIHRSTLLREQLEDDGLTETTVDDVLKSNSLAGTKTFTDAPSTLVTVAKVAGVSVFFGLHFYGFGSAWLSDLSAGNETNDTFTLYDAVADQIPIGSNGTLVTLFPTRFFLPEKLSTQIEAVVLSFIGLISTAARDKYISKFILFAFAVSASINVYLLNVARIHTTRLEDAIELKKPKKKASKTAVSVPKAVVVKDSETTKSSEILHSSSESESEQSSRPLEQVIELYKDGKVKTLVDDEVVSLVTAGKLPLYALEKQLGDNLRAVAIRRKAISDLADAPVLRSNKLPYLHYDYDRVFGACCENVIGYMPLPVGVAGPLIIDGKPYHIPMATTEGCLVASAMRGCKAINLGGGVTTVLTKDGMTRGPCVKFPSLKRAGQCKLWLDSDEGQEEMKKAFNSTSRFARLQHLQTALAGDLLFIRFRTVTGDAMGMNMISKGVEYALKQMTEVFGWDDMMVVSVSGNYCTDKKPAAVNWINGRGKSVVAEASIPKDAVVKVLKSSVKAVVDVNVNKNLIGSAMAGSVGGFNAQAANMVTAVYLALGQDPAQNVESSNCITLMTETEDGDLKVSVSMPSIEVGTIGGGTILDPQGSMLELLGVRGPADVPGENARQLAKIVASIVLSGELSLVSALAAGHLVQSHMQHNRAAAKK
What is the function of this protein?
HMG-CoA reductase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (PubMed:9647847).  In this module, the cytosolic acetyl-CoA acetyltransferase catalyzes the formation of acetoacetyl-CoA (By similarity).  The hydroxymethylglutaryl-CoA synthase then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA (By similarity).  The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase (PubMed:9647847).
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KTHY_VIBC1
Sequence: MMKANFIVVEGLEGAGKSTAIKTVLDTLKAAGIENIVNTREPGGTPLAEKMRGLVKEEHEGEDLKDMTELLLLYAARVQLVENVIKPALANDQWVVGDRHDLSSQAYQGGGRQIDASLMKNLRDTTLGEFKPAFTLYMDIDPRVGLERARGRGELDRIEKMDISFFERTRERYLELANADDSIVIINAEQSIEDVAQDIKAALNKWLAAQ
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: LEU1_VIBCH
Sequence: MNNQVIIFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDIIEAGFPVSSPGDFESVQTIAKNIKNSRVCALSRAVAKDIDAAAEALKVAEAFRIHTFISTSTIHVQDKLRRSYDDVVAMAVKAVKHARQYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGARTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDKAIISVHCHDDLGMSVANSIAAIQAGARQVEGTINGIGERAGNCALEEIAMIIKTRQELLGVTTGIKHDEISRTSKLVSQLCNMPIQSNKAIVGANAFSHSSGIHQDGMLKNKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDSMGYNENEYNLDALYEDFLKLADRKGQVFDYDLEALMHFSNLREEDDFYKLNYLSVQSGSVMATTSIKLLCGGEEKCEAAVGNGPVDALYQCIYRITGYEIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGVSTDIVEASGQALLHVINSIHRADQIAQIKQKKSVATV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: VATA_CYACA
Sequence: MTTVRVNGMKNGIIKKVSGPVVSAENMDGAAMYELVRVGNEQLVGEIIRLEGSVATIQVYEETSGLTIGDPVLCTGSPLSVELGPGLMGNIFDGIQRPLEKIAERSNSVFIPRGVNVPALDRKKVWEFRPADNLKVGDPITAGDIYGIVPETPLIDHKIMLPPNQMGKIVFLAPPGDYTLEDTVLEIDFNGQKKKFSMVHQWPVRLPRPVTEKLRADKPLLTGQRVLDALFPSVQGGTCAIPGAFGCGKTVISQALSKFSNSDGIVYVGCGERGNEMAEVLKDFPELTMTVGDREESIMKRTLLVANTSNMPVAAREASIYTGITVSEYYRDMGLNISMMADSTSRWAEALREISGRLAEMPADSGYPAYLAARLASFYERAGKVSCLGSPNRQGSITIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMKALEPYYEERFPEFLNYQQKAREILQTEDDLMEIVQLVGKDSLAENDKITLEVAKMIREDFLAQNSFTEYDRFCPFYKSVLMLRNMIHFYELANKAVEGSGEQHLTLAQIKEQMGETIYKISGMKFLDPAQGWSLF
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RR2_NYMAL
Sequence: MTRRYWNINLEEMMEAGVHFGHGTRKWDPRMAPYISAKRKGIHITNLTRTARFLSEACDLVFDAASRGKHFLIVGTKDKAADSVASAAIRARCHYVNKKWLGGMSTNWSTTETRLQKFRDLRVRAEMGQFSRLPKRDAAILKRQLSHFQTYLGGIKYMTGLPDIVIIIDQQEEYTALRECVTLGIPTICLIDTNCDPDLADIPIPANDDAIASIRLILNKLVSAICQGRSSYIRSR
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS3_METAC
Sequence: MIDLDTLKYENGLILAVVQDQKSREVLMCAYMNREALEKTVKTGIAHFWSRSRKQLWKKGETSGHLQKVKEIRIDCDMDSVLLLVEQVGGACHMGYRSCFYRNLKGEVVGEKVFEPKDVY
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG15_ASHGO
Sequence: MVADFDSGWYEGAGDELGQGARNGVLRERLGGNEKAQVVRSRRKAVAWNVLMVLGLILYVLYSACFAQARQWWRTNGMARGSQAGRFQLVQVHHHGVGAEHATHLVLDVDAEFRKEAAAEYSVFALHGEGQELWPEAGRRRAANPFEYAYALREERATVVRAQQQVPEFMEPYLDFALERPDLAEQIKMDWGYENMFVPNITDKETVISLALMSSNAYVRLPNTGNWRNVTSWNSSVEGDQIHLGWDENGLRAHVFANEDRSVVVLALKGTSSQVLPGSGDDDETSANDKLNDNLLFSCCCARVSYLWTTVCDCYIKSYTCEESCLESELRRKDRYYQAGLDMYKQVLAEFPDASIWLTGHSLGGALASLVARTYGVPAVTFEAPGELLATQRLHLPQPPGLPNQLDTVWHFGHTADPIFMGTCNGASSACSIAGYAMETSCHSGKSCVYDVVNDRGWRVNLLHHRIHTVIDKILDDYDAVAACVPPDICHDCYNWNYVRWRDGTTSPMPSSVASKPTPTPTSPGSPSSTCKGRNWFGYCTEYA
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: FRPA_NEIMC
Sequence: MTSANFNINGFGDVKLTPYSPLLGYKAWDSFIGSIQSLSDLIYNVDNNRNKMEITVNNAIQAADSFLSSIGRDNKITNTASLLASLDNIFLNLRNVSRDIRETGKFKPNDIQQAIGDIFIAAGDGLQYIKQQTEAMAQSKFLPTKLKTGLNDVLNSRMLKSSTVLQHELNYLGFKIKDYGNERLGESIMNIDDFTPSKIANFFADPDTYSNVLEEVSRFIYSLVPDDANPWKGGEDYIGRGISEWGELLEKWYKQDFLPYLEKEWDQFPKFEDWLPEFPEWAREWLKLDPKRSGKYHVYDPLALDLDGDGIETVAAKGFAGALFDHRNQGIRTATGWVSADDGLLVRDLNGNGIIDNGAELFGDNTKLADGSFAKHGYAALAELDSNGDNIINAADAAFQTLRVWQDLNQDGISQANELRTLEELGIQSLDLAYKDVNKNLGNGNTLAQQGSYTKTDGTTAKMGDLLLAADNLHSRFKDKVELTAEQAKAANLAGIGRLRDLREAAALSGDLANMLKAYSAAETKEAQLALLDNLIHKWAETDSNWGKKSPMRLSTDWTQTANEGIALTPSQVAQLKKNALVSLSDKAKAAIDAARDRIAVLDAYTGQDSSTLYYMSEEDALNIVKVTNDTYDHLAKNIYQNLLFQTRLQPYLNQISFKMENDTFTLDFSGLVQAFNHVKETNPQKAFVDLAEMLAYGELRSWYEGRRLMADYVEEAKKAGKFEDYQKVLGQETVALLAKTSGTQADDILQNVGFGHNKNVSLYGNDGNDTLIGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYDYATGRKDIIRFTDGITADMLTFTREGNHLLIKAKDDSGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLDVATVKELVQQSTDGSDRLYAYQSGSTLNGGLGDDYLYGADGNDLLNGDAGNDSIYSGNGNDTLDGGEGNDALYGYNGNDALNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGSGSDTYVFGEGFGQDTVYNYHVDKNSDTMHFKGFKAADVHFIRSGSDLVLSASEQDNVRISGFFYGENHRVDTFVFDDAAISNPDFAKYINAGNNLVQSMSVFGSNTAATGGNVDANIQSVQQPLLVTPSA
What is the function of this protein?
May participate in the pathogenesis of meningococcal disease.
What are the official names of this protein?
Iron-regulated protein FrpA.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Secreted.
Protein: DXS_HISS2
Sequence: MNKYPLLSLINSPDDLRLLSKDKLPQLCQELRSYLLESVSQSSGHLASGLGTVELTVALHYVFKTPFDQLLWDVGHQAYPHKILTGRRDKMSTIRQKGGLHPFPWREESEFDVLSVGHSSTSISAGLGIAIAAQKENLGRKTICVIGDGAITAGMAFEALNHAGSVHTDMLVILNDNEMSISENVGALNNHLARLLSGSIYSTLRESGKKILSGLPPIKEFVKKTEEHVKGFVSPVGTLFEQLGFNYIGPIDGHNIHELISTLKNMQSLSGPQFLHIKTKKGKGYAPAEKDPIGFHGVPKFDHKLGELPKSSTTPTYSQIFGSWLCEIAAQDEKLIGITPAMREGSGMVEFSQQFPQQYFDVAIAEQHAVTFAAGLAIAGYKPVVAIYSTFLQRAYDQLIHDVAIQNLPVLFAIDRAGIVGADGQTHQGAFDLSFMRCIPNLVIMTPSNENECRQMLYTGYKCGKPAAVRYPRGNAIGVKLEPLAELPLGKSKLIRQGKNIAILNFGTLLSEATKVAEDLDATVVDMRFVKPLDTQRIQEIAQTHSLIVTLEENAIQGGAGSAVAETLYQQQQKVSLLQLGLPDNFIPQGTQKEMLAELKLNAEGIFEQIKQFLQKI
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.