PharMolix/UniProtQA huggingface dataset:
Protein: PGPLE_DROME
Sequence: MSESGIKKLSQERTREWLASQEDEELESIAESSVVDSLDYDYTEEEEDADQNTSEEISTMTLGTQIATKKHSIISDTIRDLMNSINSIQTLGNVNISNSTNVHIGNVTNINGNIQIIADGLTQNRRDRRHVSPPRDNAPKTPTHFEDDYQDESEERVRSDVFIRRQKFKIPKELSAIIPRSSWLAQKPMDEPLPLQLPVKYVVILHTATESSEKRAINVRLIRDMQCFHIESRGWNDIAYNFLVGCDGNIYEGRGWKTVGAHTLGYNRISLGISFIGCFMKELPTADALNMCRNLLARGVEDGHISTDYRLICHCQCNSTESPGRRLYEEIQTWPHFYNIEEEEQ
What is the function of this protein?
Peptidoglycan-recognition protein that plays a key role in innate immunity by binding to murein peptidoglycans (PGN) of Gram-negative bacteria and activating the imd/Relish pathway.  Has no activity against on Gram-positive bacteria.  Binds to diaminopimelic acid-type PGN (DAP-type PGN), an activator of the imd/Relish pathway.  Functions synergistically with PGRP-LC in producing resistance to E. coli and B. megaterium infections, which have the DAP-type peptidoglycan.  Acts both upstream and in parallel with PGRP-LC in the imd/Relish pathway, and is required for infection-dependent activation of melanization.  Required for Relish processing and nuclear translocation following proteolytic cleavage.  Its localization suggests a role in the recognition and subsequent activation of the signaling at the first point of contact with invading bacteria.
What are the official names of this protein?
Peptidoglycan-recognition protein LE.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted. Note=However, no signal sequence are predicted by sequence analysis tools.
Protein: GLUQ_PARMW
Sequence: MPVPDHLLLELERGQRWRADGTYRGRYAPSPTGALHLGNLQTALLSWLQARQAGGVWLLRIDDLDTPRNRPGAVEAIQADLHWLGLDWDGEPILQSCRRGLYASWLSWFRRSGALFPCRCSRRELAGLARYPGTCRDGGAGWGWRDRRLPSWRLRVPSRDPDGSGDVVVRRADGFIAYQLATVIDELALGITDVVRGEDLREALPAQRSVYRALQQQPPRFHHGPLRCDAEGRKLSKREASSGLMALRELGLDAPAVVGLLASGLGYGPPGARLSAIELLEDLTQKGIRAGHS
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: TX21A_ETHRU
Sequence: MIVSLRCCLLLVALLITVETAIMSKRDIVCSVSGDVACNLECELLHKKKGSCDENGACTCFNKKRETE
What is the function of this protein?
Antibacterial peptide mostly active against Gram-positive bacteria.
What are the official names of this protein?
U-scoloptoxin(02)-Er1a, U-SLPTX(02)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_PSEP1
Sequence: MTDHALLLVNLGSPASTSVADVRRYLNQFLMDPYVVDLPWPVRRLLVSLILIKRPEQSAHAYASIWWEEGSPLVVLTRRLQAAMVEHWPHGPVEIAMRYGQPALPDVLERLAAQGVRKVTLAPLYPQFADSTVTTVVDLAKQTVSERQLPLQMRVLQPFYEHPAYIEALAASARPHLETGYDHLLLSFHGLPERHLKKLFPKGVKHDLRAADCCHGATAEVRSVCYRGQCLATAKAFAQKMGIPDGKWSVSFQSRLGRDKWIEPYTETRLDELAKAGVKKLLVMCPAFVADCIETLEEIGMRGSEQFVEAGGRELVLVPCLNDHPEWVRVLADMCEKA
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYEF2_MOUSE
Sequence: MADADKSEAAAGDDGSQQQPAEPRRDTHPGEPEKPPRSSANGVKMENDESVKEEKSDLKEKSTGNKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGTSFQGSHASDVGSGLVNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDYRSHDSKTSQLPRGLGGIGMGLGPGGQPISASQLNITGVMGNLGPSGMGMDGPGFGGVNRIGGGVGFGGLEAMNSMAGFGGVGRMGELYRGAMTSSMERDFGRGDIGLSRGFGDSFGRLGSAMIGGFAGRIGASNMGPVGTGISGSMSGMSTVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDVDRGFLSGPMGSGMRDRLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKACRIMNGIKISGREIDVRLDRNA
What is the function of this protein?
Transcriptional repressor of the myelin basic protein gene (MBP).  Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter.  Its binding to MB1 and function are inhibited by PURA.
What are the official names of this protein?
Myelin expression factor 2, MEF-2, MyEF-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS8_ECOSE
Sequence: MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALRAEQV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ASK20_ARATH
Sequence: MSEGDLAVMKPETMKSYIWLQTADGSIQQVEQEVAMFCPMICQEVIQKGVGSSKNHAISLPQRVNPAMFSLILDYCRFHQLPGRSNKERKTYDERFIRMDTKRLCELTSAADSLQLKPLVDLTSRALARIIEGKNPEEIREIFHLPDDLTEEEKLEPLKNSMDDPRIRLLNRLYAKKRKELKERERLKNVEVEEHVDERSVDDLLSFINGRDHKAVKMSKGKKKKKKKKDQKIVSSNNIHDKESHDLRSKQQCVEEIGSSMREVPNLLSAEDDISTPNAGSEDEDIDDEIDPAMRELLDREVEDFAQRLNSNWVRSLGKERRPVHFSINGNGTTRRHTGMVSIWRPCMFTLF
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).
What are the official names of this protein?
SKP1-like protein 20, AtSK20.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ABRX1_MOUSE
Sequence: MEGESTLGVLSGFVLGALTFHHLNTDSDTEGFLLGEMKGEAKNSITDSQMDNVKVVYTIDIQKYIPCYRLFSFYNSLGEVNEHALKKVLSNVRKTVVGWYKFRRHSDQIMTFREQLLHRNLQTHLSSPELVFLLLTPSITTESCSTHCLEHALYKPQRGLFHRVPLVVTNLGMSDQLGYKTEPASCTSTVFSRAVRTHSSQFFNEDGSLKEVHKINEMYAAVQEELKSICQKVEQSEREVEKLLMDVNQLKEVRRTQQARATGAGEKNVQRNPQENILLCQALRTFFPESEVLHSCVISLKNRHISPSGCNVNHHVDVVDQLTLMVEYVYSPEASPVPTAQLRKRKALDTHDQGSVKRPRLLETESRPSVAASRSRHQDKASSSSLDIDIEMGSPEDDADYPRSPTF
What is the function of this protein?
Involved in DNA damage response and double-strand break (DSB) repair.  Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1.  The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.  This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
What are the official names of this protein?
BRCA1-A complex subunit Abraxas 1, Coiled-coil domain-containing protein 98, Protein FAM175A.
What is the protein family that this protein belongs to?
Belongs to the FAM175 family. Abraxas subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: NU3M_DROSU
Sequence: MLSIILIASLILTIVTIVMFLASILSKKALIDREKSSPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPMIIIMKFSNIMIWTTTSIIFILILLIGLYHEWNQGMLNWSN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: VESP_NAJKA
Sequence: SPPGNWQKADVTFDSNTAFESLVVSPDKKTVENVGVSQVAPDNPERFDGSPCVLGSPGFRSGKHFFEVKYGTQREWAVGLAGKSVKRKGYLRLVPEERIWQKGLWWLG
What is the function of this protein?
Neurotoxin that produces dose-dependent hypolocomotion and hyperalgesia in mice.  May directly act on the central nervous system, as it is 6500-fold more potent when administered intracerebroventricularly than intraperitoneal.
What are the official names of this protein?
Thaicobrin.
What is the protein family that this protein belongs to?
Belongs to the ohanin/vespryn family.
What are the subcellular locations of this protein?
Secreted.
Protein: T23O_SACEN
Sequence: MVHGNSRPLEKDVVRDLRRELSYGQYLRLDRLLDAQHPVSEPEHHDELLFIIQHQTVELWLKLILHELRTAREHLARDELKPALKQLARVKHVQHTLTEQWSVLATLTPAEYVEFRGFLGRSSGFQSYQYRAIELILGNKNAEMLEVFAHDEFAHELLNGLLKEPSVYDEFVRLLHRRGHDVPAAFLQRDVSLPHTFTPELVPLFRGIYETAAENWDAYEACEELVDLEENFQFWRFRHLKTVERTIGLKHGTGGSSGVSFLRRALELTFFPELYAVRTEI
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: RL6_VIBA3
Sequence: MSRVAKAPVAIPAGVEVKLNGQEVTVKGSKGELTRVLNSAVVIAQEENNLTFGPKEGVTNAWAQAGTARALVNNMVVGVTEGFTKKLTLKGVGYRAAMKGNAVGLTLGFSHPVEHALPEGIKAECPSQTEIVITGCDKQVVGQVAADIRSYRAPEPYKGKGVRYADENVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: EIF3L_MONBE
Sequence: MEQETFEEQEITVADINANVPQEVQNYLRSFNKAIQEKSLKEIEEHYEYKWRRTTDQYFKDSRWPEPVYIQAMFEQEGQEDSYFVSLYPELYYRDVYYRSSNTNIEITVEDRHASYDHYIELINMFVEPDAPLDLELPNKWLWDMIDEFLYQFQDFVIFRSRVDDAKTESDYQEIAERPNAWNVTIVLNALHSLILKSEINEQLEAYRSGQNPTEMAGAFGKSSLYKMLGCFSLVGLVRLQCHLGDYRQALQIMKNVDLDRRFIFSLVPACNVSLHYHLGFCYLMLRRYQDAFRLFESILIQMASHRGPGHYDGGRKRDTIVCLLALAYSLLPQRLERSVEHLMNEKEGENIRKIQSGEGADEAINHLLLRGAPRFLCPFLADPQQPPEEDVLKAESERQLELFKQEAKQLILLGQIRSYLKLYTRMKLEKLAKFLELTVPQLRSMLHSFKHKMSQIVHTPGGEPLAGERQFTDSVDFYVDGDEICIATMTVKKSYGDDFLTASLKMVTSNR
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_HYPBU
Sequence: MILSDRDIAWYIEKGLLRIDPLLDDTIRENGVDLRLDSEFCRFNPDAPELDTRKPFNREIYYNCVKVDPEQGFTVKPYEHVLATTMETVCLPDDLVGLVNVRSTFARYGIFVPPTVIDAGFCGQITIEIIGSAYPVRLYPGQRFLHVVFVRTTSPVANPYHGKYQGQRGVTPPRPD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: MDM34_ASPNC
Sequence: MAFNFNWSPLMADASFYTRAQELLTAALNKSPKPPIIVDDIHVTELNLGSIPPELEILEIGDLAEDRFRGIFKMSYTGDAFLTLKTRVQANPLNTYLLTRPSFATPLPVAAATPLTIPLQITLSDFKLSGFVILVFSKQKGITVVFRNDPLESLKVSSTFDSIPFVRDFLQREIEGQLRVLFMDELPAIIHRLSLRLWVPEYRAGEEMANRATNTAGEGPGQDPLASPPQDPVDAQGNALDESEIASLSLDSSVETHSLFSQKNLLRLAALTDSQRTLSLFTPSIQEVVYRAWTSPSDAGEVSGGVMSPLSPVLSRTQSQVGGMSSFHDTASMVSSQTRSSTNTHTFSSYGLSLGAGRHSKSNARRRKKRVVDLRRPKTTEDAVSVSGESTYTETTSAPSICSAPLPVVSEQTDDPVTPPLSPDSELHLPTVPERHRLSISRQMPRRDIATEMLRETGESSAQPVNHSAVDVNATPRVAVHPYIAAQHESEKEEASAPRQLPSKALPLSDAKPTSSIVDQALVERLAGEIARRMREEKLTPGNSCSSFWDRLSHDDAPPAYGQ
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: CITX_ECO8A
Sequence: MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRSCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
What is the function of this protein?
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.
What are the official names of this protein?
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, Apo-ACP nucleodityltransferase, Holo-ACP synthase, Holo-citrate lyase synthase.
What is the protein family that this protein belongs to?
Belongs to the CitX family.
Protein: AROB_PICTO
Sequence: MDLKYKLGNDVIRIVTGKNILKDFACELNSGGNISIISRNVYKKYDLSFIKNRIIIDDGERAKSMEYLTLIINELLNKRVERGDSIIYIGGGTTGDLSGFAASIYKRGMGLIAVPTTLLAQVDSSIGGKNGINYMNIKNLIGTFYNPKLIIDDISFIDDKKLMMDGLAESLKMGITIEPELFNIINNDPDYIIENIERIITLSINAKLSIVSKDFHDKKHLRYVLNFGHTIGHALESYFNNNISHGEAVANGMIIEAYISKCLGNADISNEIRSIIKRLGFKIIDFRSVDINRLLEYIKNDKKSESGYINIVAVNGIGRYKIEALSPEEMLKILGGMP
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFA_BRADU
Sequence: MTIALHPSIDNGLKQGSGSFAGGTLACKCKDHQVKVGIKGDVAHNHACGCTKCWKPQGATFSVVAVVPRQNVTVLENGDKLEIVDASAVIQRHACKACGTHMYGRIENKNHPFYGLDFIHPELFQEQGSQAPQFAAFVSSVIESGVKPEQMAGIRSRLKEIGLEPYDCLSPALMDAIATHVAKAKAA
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: CH60A_DROME
Sequence: MFRLPVSLARSSISRQLAMRGYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEEIAQVATISANGDQAIGNLISEAMKKVGRDGVITVKDGKTLTDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALLLLSEKKISSVQSIIPALELANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVEEGIVPGGGTALLRCIEKLEGVETTNEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAGDYGYDALKGEYGNLIEKGIIDPTKVVRTAITDASGVASLLTTAEAVVTEIPKEDGAPAMPGMGGMGGMGGMGGMGGMM
What is the function of this protein?
Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
What are the official names of this protein?
Heat shock protein 60A.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: AXHA_ASPSO
Sequence: MKVTKKVLDQSLCCTALLALVGGAAAQCALPSSYSWTSTGALAEPKAGWAALKDFTNVVFNGQHIVYGSVADTSGNYGSMNFGPFSDWSEMASASQNAMSQGTVAPTLFYFAPKDVWILAYQWGPTSFSYKTSSDPTDANGWSAAQPLFSGTISDSDTGVIDQTVIGDDTDMYLFFAGDNGKIYRASMPIDNFPGDFGTQSEIILSDTKENLFEAVQVYTVDGQNKYLMIVEAMGANGRYFRSFTADSLDGEWTVQAGTESQPFAGKANSGATWTNDISHGDLVRNNPDQTMTVDPCNLQLLYQGRDPNASGDYNLLPWKPGVLTLQV
What is the function of this protein?
Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Releases L-arabinose from arabinoxylan.
What are the official names of this protein?
Alpha-L-arabinofuranosidase axhA, Arabinoxylan arabinofuranohydrolase axhA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 62 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BP01_APIME
Sequence: MVPVPVHHMADELLRNGPDTVI
What are the official names of this protein?
Brain peptide MVPVPVHHMADELLRNGPDTVI.
Protein: HPPK_SYNY3
Sequence: MAPVSPTDFPQQCHGAVVGLGGNIGPVLDNLQGAIAELALVAGIEVERCSSWYRSRAFGPPQPDYINGCVTLRVSLSPPELLQTLLAIEQKFGRIRLEKWGPRTLDLDLIFYGDRQLEQARLTIPHPQMQYRPFVLVPLAEIAPDWVDPRSGKTIIQLIEQVDCTAVWPVAPGLELGGSLEPEQVFAPGAVAVHG
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: QUEC_STAS1
Sequence: MSEQTLDNNKAIVVFSGGQDSTTCLFWAKKHFESVELVTFAYGQRHDTEIEVAKQIADEQGVKHHLLDMSLLSQLTPNALTQHDLDIEVGDDGIPNTFVPARNLLFLSFAGALAYQTNAKHIITGVCETDFSGYPDCRDSFVKSMNVTLSLSMDKDFVIHTPLMWLDKKATWALSDDLGVLDYIRYNTLTCYNGVIGDGCGECPACQLRANGLNAYLAEKGVD
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: YCIW_ECOLI
Sequence: MEQRHITGKSHWYHETQSSTTEYDVLPLVPEAAKVSDPFLLDVILEKETLAPFLSWLDPARVLAVDLFPDQLTVTRSQTFTAYERLSTALTVAQVCGVQRLCNYYSARLTPLPGPDSTRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTAWDCVIISQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESLRWRSSYEVEKLPEEHTKSSTAELCQLAEILSLHPISLSLLEKLLNSTRGNTQPDNQLAALLCARINGSPACFATCMDSSNEYKKISTLMRKGENEINQWADRHSVERATVQAIQWLTRAPDRFSAAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY
What are the official names of this protein?
Uncharacterized protein YciW.
Protein: VSY3_TRYCO
Sequence: MLDNSRARSIVHLLILLKAHVITQIIKNTQEFTSLCTFVKVTLKATDGLTSAASKSQTDWALGENPTSRIKKLITELETSSDRIRLGEEPNLTIQLPQGDPKQRLRRKLEVFLARAKYTEELVRQAQGDVGGRCNEAKAELEEAVTGRKGPDLETQATAAAAALHNKARGTACKVAGATTDTNFAGTSLVADLMCLCAAETNSREKHICGFESHASGVWANAGTNSNAGEIWGKILDACKNREIQVEVTPQFLRIAITKFEGLLGAQAHKLTSNGNAGAWLLGYSMNAGSVTCDGQSSTNGICVDYKGSSDARGPIAWLGHIKNAITALENRDKNLQRVRKLQRQAEAILMSAEDALIEANISLGGKDMVPASEVTVPNSSNPTSRQNSVVQEPTTVSAAAITPLILPWTLLI
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein YnAT 1.3, VSG.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: PP4P2_XENLA
Sequence: MAADGIDERSPLISPSSGNVTPTAPPYIQENNLQAELPPPYTAIASPDAGGVPVINCRVCQSLINLDGKLHQHVVKCTVCNEATPIKTPPLGKKYVRCPCNCLLICKDISRRIGCPRPNCRRIINLGPVMLIPEEQPAQPALPVQPDGTRVVCGHCGNTFLWMELRFNTLAKCPHCKKISSVGSALPRRRCCTYITMGMICIFIGVGLTVGTQDFARRFHATYVSWAVAYLVGLVCLVRACYWGAIKFSYPEHSFA
What is the function of this protein?
Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
What are the official names of this protein?
Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase, Type 2 PtdIns-4,5-P2 4-Ptase, PtdIns-4,5-P2 4-Ptase II, Transmembrane protein 55A.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein.
Protein: Y3121_YERPE
Sequence: MFGKGGIGNLMKQAQQMQEKMQQMQEEVAKLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLVEDDKEMLEDLIAAALNDAARRIDETQKEKMASVSNGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YPO3121/y1061/YP_0808.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CCA_YERPY
Sequence: MNIYLVGGAVRDSLLNLPVTEQDWVVVGATPEQLLKLGYQQVGKDFPVFLHPVSHEEYALARTERKSGQGYTGFTCYAAPDVTLEDDLLRRDLTVNAIARSADGEFIDPYHGKQDLENRVLRHVSDAFGEDPLRVLRVARFAARFAYLGFTIAPETMSLMSNMAQSGELSALTPERVWKETEKALKTQSPHVYFQVLRDCGALAVLFPEIERLFGVPAPEKWHPEIDTGIHTLMTLAIAAQLSPEVDIRFAALCHDLGKGLTPKEHWPHHHGHGPAGVKLVEQLCQRLRIPNPVRDLAKLVAEYHDLIHTVNKLRPETLLKLFNAIDVWRKPERLEQMIMTSEADARGRTGFENNPYPQGDYLRAAFQIANGVSIQEVVASGLQGLAIRDELQRRRQQALAEWKQTQETPLI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.