PharMolix/UniProtQA huggingface dataset:
Protein: SDHB2_ARATH
Sequence: MAFGLIGRVVGTKSSRLSTAARLIPARWTSTGSEAQSKASTGGGGASLKTFQIYRWNPDNPGKPELQDYKIDLKDCGPMVLDALIKIKNEMDPSLTFRRSCREGICGSCAMNIDGCNGLACLTKIESGSKETTITPLPHMFVIKDLVVDMTNFYNQYKSIEPWLKRKNPASVPGKEILQSKKDRAKLDGMYECILCACCSTSCPSYWWNPESYLGPAALLHANRWISDSRDEYTKERLEAIDDEFKLYRCHTILNCARACPKGLNPGKQITHIKQLQKSG
What is the function of this protein?
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial, Iron-sulfur subunit of complex II, Ip.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: HIS2_LACP3
Sequence: MTQAKQSIPALYDFIKERQANPVAGSYTDYLFTKGLDKILKKVGEESTEVIVAAKNPDDPAFILEVAALTYHVLVLMVERGITVDQIATELASREGKKSRLQERSKIEKY
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDB_HOTTS
Sequence: VTMGYIKDGDGKKIAKKKNKNGRKHVEIDLNKVG
What are the official names of this protein?
Non-cysteinic peptide Bs 10, Bs10, Non-disulfide-bridged peptide 2.1, NDBP-2.1.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DPM3_SCHPO
Sequence: MQRIHKVILYYVSLTILYRVTYLFDLEEPWSTLRPYTPYLFILAFGSYLGITLLYNVATTNDKPEAYVDLVKDIKEAQDALRSKGMTIED
What is the function of this protein?
Stabilizer subunit of the dolichol-phosphate-mannose synthase complex.
What are the official names of this protein?
Dolichol-phosphate mannosyltransferase subunit 3, DPM synthase complex subunit 3, Dolichol-phosphate mannose synthase subunit 3, Dolichyl-phosphate beta-D-mannosyltransferase subunit 3, Mannose-P-dolichol synthase subunit 3, MPD synthase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the DPM3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ATPB_NITEU
Sequence: MSHQGKIVQCIGAVIDVEFTPGEIPKVYDALVMEGSELTLEVQQQLGDGVVRTIALGSSDGLRRGMMVTNTQKQISVPVGTKTLGRIMDVLGRPIDEMGEIGANSLMPIHRAAPAFDELSASTELLETGIKVIDLVCPFAKGGKIGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEAFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSSKTGSITSIQAVYVPADDLTDPSPATTFGHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPLIIGEDHYNTAREVQQTLQRYKELRDIIAILGMDELSPEDKLSVSRARKIQRFLSQPFFVAEVFTGSPGKYVPLKETIKGFKGIVSGEYDDIPEQAFYMVGGIEEVLEKAKSIQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GH_SHV21
Sequence: MTILQLFLVFLNILEALCDYQLPKPRINKPPAEERLKLRNGYNTTLIEFDDGVQSFNLNWTKIIEHIPHDELIELWREANVTEPLVNTLLKRSDTYRPETNVHIPGHGNSYACALPYWSYTIDQWEDNKTTGYLGNFGIPSKTVLNEFFYDFQYVYTNRQFYTEATYVLNCLIGATTPAYPTISCHITPNYLFVSVEFTKFDSLTLLFGHSHYLPPLKGHIVYNDIEGASNDVFSLVIFSTYDLFGKHVESFKFDIAKVFREIIETPPLTFIKNLQDEMFTIEIRDGCNINNIVNPKTFLFAFKAVVAHFLVIDSLRTQQHILLNCFANYMSELEFLRKLMESCFEFFEFDFPYTVIETLAASQALNVPKHVITSLSHQDKTNMLSLFRLSRHSKHVSAVAISEIIDLISHIYTAYSYTYMLTSSERKMLLDAYIVLNDIMHKNETVKKQDLLPYVLSSSMCTSLEIGNLLLHFGQKDVLDVYETFSPCYLSLRFDFTKEKLITEFPQSSLIAQKEINLGTNGFFQTLHMRHHTSLEILPIIKCIKSLSTDIILSIPLKNITYVISTKPVPNSKIYDVSEVFLKTSMIISAVNNDCKPYQGGSAAHQIPVIYNVTVPRRGCPYCSSVVLSYDESQGFQSMMYITDTYVQENLFTEHSPFFGDGNLHIHYLILMNNGTVIEVRGAYRARLVNFIIVIMVFILFLVGLYLLYKLFVYLT
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: HIS1_MARMM
Sequence: MTSRLRIAVQSKGRLAEGGMDLLKRCGLRFAYGRDKLHQRAENMPVDLMLVRDDDIPNFVGSGACDYGIVGENVLAEEQAAGGRARELEVALRLGFAGCTLKLAAPDDGSIRTVADLEGKAVATSYPALTAQYIADRGVKAEIVEMRGSVEVAPRLRIADAICDLVSSGATLQANGLKAFETVLRSEAVLIRRKSGRADDTDAIANILMRRSEGVIASSQTKYIMLNAPTDRLGAIRALLPGADAPTIAKVAGREDVVAVHAVCRERVFWETLEALEKEGARAILVLPIEKMLA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF2_VAULI
Sequence: MLKFSFLFLTVEKPGGLFDFDGTLPLIAIQFLILMFLLNILLYTPLLKIIDERSEYIANNLQEASIILNKANELSSQYEKEFSKIKKEVELDSLTLQNLHKNILEIEIISSQKIFENYLNQTINNFDSEKEKILTSLDEEINSLSSEIITKIVA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', chloroplastic, ATP synthase F(0) sector subunit b', ATPase subunit II.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y854_ENCCU
Sequence: MSKMDKLAKFEKFDLFFAAIACICGILKVMEMGKEGYPTLGTVSKNGMAVLAVLVALGFLLKYADQMCRRITSHSFSEKGGFLNPCVILSVIEFFMMLICIKAMLFYPAEIPGVDDSSQMEPPISSKFGLFGAIFMPYIFAECIRLLLANKNSRRDRVILGILVLGCLAMAGLAYLEYKGKGNFISAGILGVGLSMLLSRLALVDEDEEDTLLDDSAEGGNVWMYLAMFASFTLVLILLARSHRILFDNLSFLDSLKSFTFLGRKVSQMASEDPPKDPLPRQEGGGGDTIA
What are the official names of this protein?
Uncharacterized membrane protein ECU08_0540.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GALD_RHIME
Sequence: MTLPSSQFPDLRDRGVLVTGGGSGIGAALVEAFARQGARVAFVDIAAESSLALCEKVAAQTGQAPHFIQADLRNVEAVRAAADEAVAKLGSVRVLVNNAARDDRQALEAVTEESWDESLSVNLRHLFFMCQAVAPHMQRQGGGSIVNFSSIAFLLNMPEIPAYSTAKAGIIGLTKSLAGKLGPDNIRVNAILPGMIVTERQRRLWLTEESIARMQERQCLKRMLVADDLVGPCLFLASDSSAAMTAQAMIIDGGVF
What is the function of this protein?
Involved in the degradation of galactose via the DeLey-Doudoroff pathway.  Catalyzes the oxidation of galactose in the presence of NAD(+).  Uses NAD(+) as a hydrogen acceptor more efficiently than NADP(+).
What are the official names of this protein?
Probable galactose dehydrogenase GalD.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: NADK_GRAFK
Sequence: MKIGIYGQFYHANAAQYIGQLLELLDQRNIEVLIEEDFLKLIHSNNKIEKDYKHFSAFEELDNSFDLFFCIGGDGTILKSINYIRNLDIPIVGINTGRLGFLATIQKEQIESTLEELLEKKFSLSPRSVLTMQTNPRSYDPVFSHIALNEIAVSRKNTTSMITVDTWLDDQYLTSYWADGLIISTPTGSTGYSLSCGGPVITPDADSLVITPIAPHNLNARPLVIKDHTTIKLKVSGRGKEHLVSMDSRIATLQNDTEIIIKKAPYTINFVELQGDSFLNTLRKKLLWGEDKRN
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS15_SOLLC
Sequence: MSHLDVFRKFTDDQGNYNKELVNDTHGLLSLYEAAQFRVHDEEILDEAINFTTTHLKLLLPKLSNSLSMQVSYALKYPINKTIARVATRKYISFYQEEESSCDQVLINFAKLDFSILQKMHKRELCDITRWWKELDLANELAFARDRVVELYFWCLGVYFEPQYKVARNILTKVLCFVSITDDIYDTYGTLHELTLLTNAIERWNLDATENLTSYMKLFYTGLLHFYNEVEKELEKENKSFRVNFAISEMKKLVRAYFQEAKWYHGNTVPKMEEEYMKNGIQSSANPTLATASWLGMGDEATKEAFEWISTEPPILVASSNIARLLNDIVSHEREIERGDVASSIECYMNEYGATKEEAYMEIRKIIENNWKDLNRGCLKPTTVPRVLLMPVLNLTRVAEFVYKDEDAYTFSKNNLKEVISMVLDDPIEE
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (PubMed:21818683).  No activity detected with geranyl diphosphate (GPP) and farnesyl diphosphate (FPP) as substrates (PubMed:21818683).
What are the official names of this protein?
Sesquiterpene synthase 15, SlTPS15.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: GCSH4_AQUAE
Sequence: MEDFYVEDYLVKGDRYYTKEHEWVRVKNGFAEVGITDYAQKQLGDIVYVDLPEKGKEVDAGDTLANIESVKNVAPVYAPVTGTVVEVNEDLKDEPGIINDDPYEAGWIAVIEMKDPTEVEDLMTAQDYAEYLKEIVEEEKEEEVEVKEEELIETESIEELSEEELGYEENK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein 4.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: TRAJ6_ECOLX
Sequence: MADETKPTRKGSPPIKVYCLPDERRAIEEKAAAAGMSLSAYLLAVGQGYKITGVVDYEHVRELARINGDLGRLGGLLKLWLTDDPRTARFGDATILALLAKIEEKQDELGKVMMGVVRPRAEP
What is the function of this protein?
Transfer of plasmid RP4 during bacterial conjugation requires the plasmid-encoded TraJ protein, which binds to a 19-base pair invert sequence repetition within the transfer origin.  TraJ protein is bound to only one side of the DNA helix.  This nucleoprotein structure is the initial complex in the pathway to assemble a functional relaxosome.
What are the official names of this protein?
Protein TraJ, Relaxosome protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_STRP2
Sequence: MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFHSIIDMLEPGDALVMNDTRVLPARLYGQKVETGSHVELLLLKNTSGDEWEVLAKPAKRLKVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQRIFLEVLESLGEMPLPPYIHEKLDDRERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDNLDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSGWTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFSFGDAMFIY
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIFAB_MOUSE
Sequence: MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE
What is the function of this protein?
Inhibits TIFA-mediated TRAF6 activation possibly by inducing a conformational change in TIFA.
What are the official names of this protein?
TRAF-interacting protein with FHA domain-containing protein B, TIFA-like protein.
Protein: SPA3G_MOUSE
Sequence: MAGVSPAVFGCPDVTLGRNTAVREVQENVTSVDSLTLVSSNTDFAFSLYRKLVLKNPDENVVFSPFSICTALALLSLGAKSNTLKEILEGLKFNLTETPEPDIHQGFRYLLDLLSQPGNQVQISTGSALFIEKHLQILAEFKEKARALYQAEAFTADFQQPLKATKLINDYVSNHTQGKIKELISGLKESTLMVLVNYIYFKGKWKNPFDPNDTFKSEFYLDEKRSVIVSMMKTGYLTTPYFRDEELSCTVVELKYTGNASAMFILPDQGRMQQVEASLQPETLRKWKNSLKPRMIHELRLPKFSISTDYSLEHILPELGIREVFSTQADLSAITGTKDLRVSQVVHKAVLDVAETGTEAAAATGMAGVGCCAVFDFLEIFFNRPFLMIISDTKAHIALFMAKVTNPERSMNFPNGEGASSQRLESKRLCFGDPLCLIGQ
What is the function of this protein?
Serine and cysteine protease inhibitor.  Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V.  Ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9.  Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis.  This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells.
What are the official names of this protein?
Serine protease inhibitor A3G, Serpin A3G, Serine protease inhibitor 2A, Serpin 2A.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPO11_METM6
Sequence: MNYVNILEKSKNFIELELVNDDHSLSNLIKEVLLSKKGVILASYGVEHPVLDPDTGRYISNPRIMLKTDAKTDAEKVLKEALKDIVDLCNKTLKEL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_SYNS3
Sequence: MTQQTGQDADQRPSYKDTLNLLETGFGMRANAIHREPELQAFWKEKGIDLDLGRNNPGPVFTLHDGPPYANGALHMGHALNKVLKDIINKHRLMQGRKVRFVPGWDCHGLPIELKVLQAMNQEQRQALTPIKLRKKAAAYAHKQVAGQRAGFQRWGIWADWDHPYLTLQKDYEAAQIDVFGTMALKGHIYRGLKPVHWSPSSRTALAEAELEYPDGHTSPSVYVGFPVVDLPESLRSKLNAQGLDVPAASDTLSQCLQVAIWTTTPWTLPANLAVSVNDRLDYCLADDGNGQLLIVAAELCDSIASKLERPLQAKATVKGADLAGITYSHPLLERRSAIVVGGEYITTESGTGLVHTAPGHGVDDFNTGRKHGLPVLCPVDEAGTLTAEAGPFEGLNVLKDANAKIIAALEDSGSLLLQESYSHRYPYDWRTKKPTIFRATEQWFASVEGFRTEALTAIDGVQWLPASGRNRIESMVSERGDWCISRQRTWGVPIPVFYQRETGEVLLNSDSIAHVKALIAEHGADIWWEKDEVDLLPSSHKAEAHLWRKGTDTMDVWFDSGSSWASVSSQRDGLSYPADLYLEGSDQHRGWFQSSLLTSVAVNGTAPYRTVLTHGFALDEKGRKMSKSLGNVVDPMVIIEGGKNQKQEPAYGADVLRLWVSSVDYSADVPIGAGILRQLSDVYRKVRNTSRYLLGNLHDFIPSRDAISISDLPLLDRWMLQRTATVLDQISEAFERYEFFRFFQLLQNFCVADLSNFYLDIAKDRLYVSAPNDKRRRSCQTVMALIIERLAAAIAPVLCHMAEDIWQNIPYPTGTESVFLSGWPSVPEEWRDDSLRDPMQELRELRAAVNKVLEECRSKRKLGSSLEAAVRLEARTPALQDALQWLQSKGDQEVDGLRDWLLVSQLQIGGEPWAELLASDDNELAVIEVALSRGQKCERCWHYEADIGQYSDHPGLCGRCVSVLERR
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPR_HV2BE
Sequence: MTEAPTEFPPEDGTPRRDLGSDWVIETLREIKEEALRHFDPRLLIALGYYIHNRHGDTLEGARELIKTLQRALFVHFRAGCNRSRIG
What is the function of this protein?
Stimulates gene expression driven by the HIV-2 LTR.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SURE_VIBC1
Sequence: MEMDSHNAKPLRILLSNDDGVHAQGIHALADELRSIAEVTIVAPDRNRSGASNSLTLEQPLRVTEIAPKTFSVQGTPTDCVHFALNELMKDDLPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQAIAFSLVGKQHFESAAKIARQLVEQHLIRPIPTNRLLNVNVPDLPFEELGEIEVTRLGARHHAENMIKQRDPRGHDIYWLGPPGKEQDAGIGTDFYAIEHGFVSITPLQVDLTAHESLRAMDSWLKEEN
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_SALSV
Sequence: MIGRLRGIILEKQPPIVLLETGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREELGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAVDLVLTSPASPGSEDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIRDALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: LOLB_STUS1
Sequence: MSLLKNLLAPCLALLLAGCAALGPHESVEGPGNTAAWKEHRSHVATLDGWQISGKIGIRAPQESGSGTLFWLQRQDYFDIRLSGPLGRGATRLTGRPDAVSLEVAGQGRFEAESPEALVEAQLGWQLPVSHLLWWVRGLPAPDSRSRLSIDSESRLARLEQDGWQVEYLAYAEHNGFVLPERIRLQGHDLQITLVIKDWQPRQLGR
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
Protein: ALT5_ALTAL
Sequence: MDFAKCIGDEFFGPVVDGCRGGFDFTLKFELLFFATIPPAIFLILAVPRIASLYSEPTIVAWRSWLYASKQILGFVNLVLQVTLLVMTTQGTAQFKLSGLFLSARIVTTSSTLLSVIVCHYEHSRCRRPSTILDVYLGLTLFLDIAHNRTLWLSVSSSLDAIFVRFHTTTVACKAVLAILESLSKKRLFVLHNRTTQSLDGTRGSYSLSTFSWLSRLLLSGYQNPLRLDSLPLLDEAMAVETLYARFLENTKGYLGESSGSDQKSRLPLSQALAKTLLLPLLLPILPRLVLIGLSISQAFLIQAVTGFLSAKNKADEVGYGLIGATILIYVGIALSTSLYWYYHQRFLYMARSCLTSGIFRKTTELSEATLAESQAITLMSTDIERVLAGFLNLHELWASLIQAVIVSWILWTRLKGFFALPVGLTVACFVALATVGRYIGGFQKTWMQETQKRVAMIASVLASMKQVKVSGLAATIDKKVQQARKTELRASHGVRMLQITAMTLSLLPELIAPVITLAATSESVATSNIFTIVALISLLTAPLGQLFQSVAPLMSGLACLDRIQTYLELEPVRERRGHNKSRLERIVDGPASSDEDYSYAFRVVNGSFRWQKDSPHCLQNVNLTVKHAAFTMIVGPVGSGKSTLCKALLGEISLSAGRVLVGKESEGKIAYCGQTPFLSNSTIRDNIVHFSQWNTSRYIEVIEASGLSYHLARLPDGHDTLVGSNGLLLSGGQRQLIAIARALYSDAHTLIFDDVLSGLDARTEDHVFRHIFGPSGLLRKRHDRPAVILCTQSVMYLPLADHIIVLSEQGDIAEQGKWEVLNSNGGYLQSLCVRDADATTPKVELGVEGESERNHWHTTESDEMRTKETLEQQLVVSENDEATVSGPASSGPSHVVAWSGGLANYRYYLKAVSVVALVAFLASAICYGFFFAFPTLWLNFWVRDATSKHRSHTNAFWVGIYGLFHALSLLGGFLTMYLAVTSISLVSGASLHSSIFAAIMRAPLSLFRTIDQGTLTNYFSQDITLVDGELPRSLIQFVCDLAISLSMAGVLAASSPYLAAMYPIAIALMYATVKLYLRTSRQLRILALEAKSPLYMHFLDVGRGIATLRAARLLKQYENQNDQLLEISQRPAYLLAMVQYWLLFILNIIVMFLAIFVVTLVTQLRNHGTGFAGSGLVMLLQFGQILASAMQSYAKLETSMGAVHRLKSLFEHVVSDTVGEKGISPPLSWPSKGYIKLDGVSASYMSTNEETDNTLGGLALRNIRLVVEPGQHVAICGRSGSGKSSLVLLLLGLLEPLQSTGCDAITIDGLDIRTIKQAVLSERIIAVSQDTIFLPAGASWQENLDLLGTCTTSEVKSVLENMNLWSLIESQDGGLTAAMKPEELSSGQKQLFSVARAVLRKRVKDREIRQASSIEIPSTSQLRLASDAQECKKTESDCEAVEGDSDLYCLPQLEPSNDTRLAAGREDVLGGVLLLDEFNSSMDLLTEQRYFNRIQSEFPGYTIIAITHSLASFIKDQECRQEGEAQVYRGGFFDRIIVLDSGMIVEDGHPTTLLETSHSKFRALCEAAARGEVST
What is the function of this protein?
ABC transporter that may provide the dual role AAL-toxin export and self-protection by allowing the fungus to evade the harmful effect of its own AAL-toxin production.
What are the official names of this protein?
ABC transporter ALT5, AAL-toxin biosynthesis cluster protein 5.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KTHY_BACP2
Sequence: MSGMFITFEGPEGAGKTTVIRKVHEEMERQGYAVMATREPGGIDIAEQIREVILNEKNTKMDAKTEALLYAAARRQHLAEKVEPALQRGETVLCDRFVDSSLAYQGYARGLGIDQVRSINDFAIDGTMPQMTIYFSITPEEGLKRIHANQGREKNRLDMETLNFHQLVREGYELLIAQSPERFHVVDASKPMQDVYEEVLRVIQDTLKKNQI
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TSAD_HERAR
Sequence: MLVLGIESSCDETGLALYDTQRGLLAHALYSQVKMHEEYGGVVPELASRDHIRRAIPLLEQVFSESGVAHGAIDAIAYTQGPGLAGALLVGASVACGLGLALDKPVLGIHHLEGHLLSPLLASEPPEFPFIALLVSGGHTQLMRVDGIGQYTMLGETLDDAAGEAFDKSAKLLGLGYPGGPAISRMAEFGDPTAYKLPRPMLHSKNLDFSFSGLKTAVLTVVKNQTTNICEQDKANIARAFVDAIVEVLTAKCVTALKHTGLKRLVIAGGVGANQQLRESLNAAAAKKHFKVFYPELEFCTDNGAMIAFAGAMRLQINPDAAKKDYAFNVKPRWPLDSIREI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.