PharMolix/UniProtQA huggingface dataset:
Protein: LEU3_THEVB
Sequence: MATTYRIAVLAGDGIGPEITAVALDVLRAIAPRFGLDFDFVPALVGGCAIDAVGEPLPAATLATCRQSDAVLLAAIGGTQWDSLPRHLRPETGLLALRSGLGLFANLRPAKIFPQLLHASSLKPEVIAGVDLMVVRELTGGIYFGQPRGIFTTETGEQRGVNTMAYTATEIDRIGRVAFETARKRQGKLCSVDKANVLEVSQLWRDRLTALSAEYPDVELTHLYVDNAAMQLVRAPKQFDTIVTSNLFGDILSDIAAMLTGSIGMLPSASLGESGPALFEPVHGSAPDIAGQDKANPLAMVLSAAMMLRYGLNQPAAAQAIEEAITAVLDQGYRTGDLMSEGCTLVGCREMGNLLIKELSR
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLS_STAAU
Sequence: MNKNSKKKLDFLPNKLNKYSIRRFTVGTASILVGATLIFGVANDQAEAAENNTTQKQDDSSDASKVKGNVQTIEQSSANSNESDIPEQVDVTKDTTEQASTEEKANTTEQASTEEKADTTEQATTEEAPKAEGTDKVETEEAPKAEETDKATTEEAPKAEETDKATEEAPKTEETDKATTEEAPAAEETSKAATEEAPKAEETSKAATEEAPKAEETEKTATEEAPKTEETDKVETEEAPKAEETSKAATEKAPKAEETNKVETEEAPAAEETNKAATEETPAVEDTNAKSNSNAQPSETERTQVVDTVAKDLYKKSEVTEAEKAEIEKVLPKDISNLSNEEIKKIALSEVLKETANKENAQPRATFRSVSSNARTTNVNYSATALRAAAQDTVTKKGTGNFTAHGDIIHKTYKEEFPNEGTLTAFNTNFNPNTGTKGALEYNDKIDFNKDFTITVPVANNNQGNTTGADGWGFMFTQGNGQDFLNQGGILRDKGMANASGFKIDTAYNNVNGKVDKLDADKTNNLSQIGAAKVGYGTFVKNGADGVTNQVGQNALNTKDKPVNKIIYADNTTNHLDGQFHGQRLNDVVLNYDAATSTITATYAGKTWKATTDDLGIDKSQKYNFLITSSHMQNRYSNGIMRTNLEGVTITTPQADLIDDVEVTKQPIPHKTIREFDPTLEPGSPDVIVQKGEDGEKTTTTPTKVDPDTGDVVERGEPTTEVTKNPVDEIVHFTPEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPEVTKEEIPFEKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDEITQFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPEVTKEEIPFEKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDEITQFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPEVTKEEIPFEKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPVDEITQFGGEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPVDDVTKHGPKAGEPEVTKEEIPYETKRVLDPTMEPGSPDKVAQKGENGEKTTTTPTTINPLTGEKVGEGEPTTEVTKEPIDEIVNYAPEIIPHGTREEIDPNLPEGETKVIPGKDGLKDPETGEIIEEPQDEVIIHGAKDDSDADSDSDADSDSDADSDSDADSDSDADSDSDSDSDSDSDSDSDADSDSDSDSDSDADSDSDADSDSDADSDSDSDADSDSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDADSDSDADSDSDADSDSDSDSDSDADSDSDADSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDSDADSDSDADSDSDSDADSDSDADSDSDADGDSDADSDSDADSDSDSDSDSDSDSDSDADSDSDSDSDSDADRDHNDKTDKPNNKELPDTGNDAQNNGTLFGSLFAALGGLFLVGRRRKNKNNEEK
What is the function of this protein?
Could have a role in preventing adhesion at some stages during an infection.
What are the official names of this protein?
Surface protein, 230 kDa cell-wall protein, Plasmin-sensitive surface protein.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: ENO_CALBD
Sequence: MKVDLSITAVKAREILDSRGNPTVEVEVVVNDEFVGRAAVPSGASTGIFEAVELRDGDKKRYMGKGVLKAVENVNEVIAPEIIGMNALNQVEIDKLMIELDGTENKSKLGANAILGVSLAVAKAAANALGLPLYQYIGGVNAKYLPVPMMNILNGGKHADNSVDLQEFMIMPVGAKSFSEALRMCAETFHHLRNVLKARGYNTTVGDEGGFAPNLKSNEEPLEVIVEAIEKAGYTPGKDIAIALDPATSELYNEEDGKYYFEREGKVRTKEEMVEFWVKLVEKYPIVSIEDGVAEEDWEGWKMLTEALGNKIQLVGDDLFVTNTKRLAKGIELGVANSILIKLNQIGTLTETLEAIEMANRAGYTAVVSHRSGETEDTTIADLVVAVNAGQIKTGAPSRTDRVAKYNQLLRIEEELGSVAVYPGMNAFFNLKKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CSG_METTL
Sequence: MAMSLKKIGAIAVGGAMVASALASGVMAATTSGDVAGFMKNAIKEDGTPNVDIVVGSGAAVMDVVSAADVAAKIGSMAYKTGVVEDRSAVVKVSAKAESDDVNIFTLNATNEDIALVAAADSDYAKGFINGSDQLKVTDQLASGSIQDVNDADFNATSLGDVSTMLKVPDIDPSDWYSNDDDAGEVVFTRIVYDSDKLSIDEDQILYASIAYKNDEDVFNDNNTVTLKPGMRIPFLGEEYAVVKIDDEDDIIYLGKEAKDGVLKEGEXFAVGNGYEVKIASILKSGDTSTEYSVNVQILKDGKVVKEKTDTVGGSSSAQLKLAYKDVGVVVNDAWEDIAGTTGYAEVLITKDTKALELGEEYIPDWEAYAALNNSDKLEIKKDITESDKANIIGIALKYVGDKKKKLGDRDEVDIANYLKLVFDDEDKNDVLKVKFLMDESKEVTLDIGQKATVLNAEVRLKDILADAQQSVKLTAPIAKLDSEVSLDTADKNLILVGGPVVNALTKELVDAGKVAIDNTSPATLAVVEGAANGNDVLVVAGGDREATREAAKALLEMI
What is the function of this protein?
S-layer protein.  The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of the cell.
What are the official names of this protein?
S-layer protein, Cell surface glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the Mj S-layer protein family.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer.
Protein: IOVO_CORAL
Sequence: IVTVDCSDYPRPVCTLDYMPLCGSDNKTYSNKCNFCNAVVDSNGTITLSHFGRC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: TABA_SHIFL
Sequence: MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGAPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
What are the official names of this protein?
Toxin-antitoxin biofilm protein TabA homolog.
What is the protein family that this protein belongs to?
Belongs to the TabA/YiaL family.
Protein: DCL_SOLLC
Sequence: MASICTSNFHFLCRKNNSSPISHHLLLSPSSLSFSRCGGLRLCRCAAVKTGSEGGGIRSDNAELLRKPVISTELETTSESEELVKEESDDEVGKKSGDGEGWVDWEDQILEDTVPLVGFVRMILHSGKYAIGDRLSPDHQRTILQRLLPYHPECDKKIGPGVDYITVGYHPDFENSRCLFIVRKDGETVDFSYWKCIKGLIRKNYPLYADSFILRHFRKRRRND
What is the function of this protein?
Has a function in the early stage of chloroplast development and palisade cell morphogenesis (PubMed:8861949).  Required for correct plastid ribosome assembly.  Required for processing and maturation of 4. 5S rRNA (PubMed:15010617).
What are the official names of this protein?
Protein DCL, chloroplastic, Defective chloroplasts and leaves protein.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NADK_CHLAA
Sequence: MLERVAVLYNPLSDASIKLSRELADWLVERGVKTTRGVSQEFRDQPHLVADCDLMIALGGDGTVLRAARLCFPHNIPVLPVALGHLSFMAEIGPDEVYSGCEQIMNGGGWFDERSLVRAQLWRGGQKLSQHTALNEVVISRSDLSRIVNVHVTIDDSPLTTYHADGVIVATATGSTAYALAAGGPIVDPRSQALVLVPIAAHLTNIPSMVLHEDAVVTMQLRSRHHALLAVDGRENIDLIEGDEVVVRRSPQVCTFVRLRPSNQFYTQLVARLRRS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKI35_ARATH
Sequence: MEKEGVCDTINLSDQMYPDEPFCSEMKTETIASSQKFEGGEGSKVVFSREAPLIGKDSAGTNSGECCGCSAKKLNFKGDDDLVEKENIEQQKKLNRQERIELGRLFQGAVTSLDWELAERLIQLADPQTLNDLLCVGLDSVWFLSTKPEFQGITGLIKKIICHGAHDFTRATLRTSFLASCVSACQSRTMSLSDTVTVMAQRLHERLQECNGDEILKAEAGAKVQKFTEWALKCIGFHSRCQGAKDRVSQNSAAEIELQLSAFKMFLDLAGNHLSGRDFTEAFDAACFPLTLFSNSFDPGWASGMSATVIQGLLGMLVEGGADNVNQCFLEASRFGSTELVRVLLQIAQRNSLDVDVDLALGFASHYCKIGTMKCLVEEGNAIAFLGPLMRAAERGCMQVVQWFVKRGCRDMELCLALTAATSSCQVEVAAYLLPRVPPPVLTALSIEILKAAGERSGGSLQGVEFLLKSDFLGDSTATYSVADSIARSSEDESVPSDLKSFLQEHWSESAFEKGMRESHDDFMNFMRVLKKGESAISLRDLPAPLRVAIAYMPLYRECMKADGRLLSQRLRGQLVEAVRQLQGCAVAVVEVSQTRNLMAVLEHHLTAIFD
What are the official names of this protein?
Ankyrin repeat protein SKIP35, SKP1-interacting partner 35.
Protein: MRAZ_ECO5E
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TATB_ARATH
Sequence: MAMALQIIASSSSSPTITKSHLFSYPPLQSRYKASKPNLSSWFSLLGSSRFSPYIGLKHLGISISPKSSNPEKKRRCKSMMIRASLFGVGAPEALVIGVVALLVFGPKGLAEVARNLGKTLRTFQPTIRELQDVSRDFKSTLEREIGLDDISTPNVYNQNRTNPVQPPPPPPPPSVPSTEAPVTANDPNDSQSPKAYTSEDYLKFTEEQLKALSPAESQTEDQTQTQEPPQPTTVQTPTGESQPNGTARETTAASPPRQD
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane.  Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation.  TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation (By similarity).
What are the official names of this protein?
Sec-independent protein translocase protein TATB, chloroplastic, Protein HIGH CHLOROPHYLL FLUORESCENCE 106, Protein TWIN-ARGININE TRANSLOCATION B.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=The C- terminus is located in the stroma.
Protein: RL6_BRUO2
Sequence: MSRIGKKPVPVPAGVTASVEGQTVKAKGAKGELSFVVHDEVLVKMEDGAVRVDPRDQSKEARSKWGMSRTMISNIFVGVKDGFEKKLEISGVGYRAAMQGKNLQLSLGFSHEVVYDVPAGITVAVPKPTEIVVTGIDKQQVGQVAAEIREYRGPEPYKGKGVKYAGEKIVRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ATPA_HALHL
Sequence: MQVNPSEISELIKRRIENFDAAAEARNEGTVVSVGDGICRIHGLADVMFGEMLEFPDDTFGMALNLERDSVGAVLLGDYQHIKEGATVKCTGRILEVPVGDAMLGRVVDALGRPTDGKGPIKTEGSEPIEKVAPGVITREGVDQPVQTGLKAIDSMVPIGRGQRELIIGDRQTGKTAVAVDAIINQKDSGIKCIYVAVGQKNSTVANVVRKLEEHGAMDNTIVVNAGASESAAMQYIAPYAGCAMGEYFRDRGQDALIIYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERASRINAEEVERRTNGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIYLETDLFNSGVRPAVNAGLSVSRVGGSAQTKIIKKLGGGVRLALAQYRELAAFSQFASDLDETTRQQLERGKRTMELMKQGQYEPQSVGEMAFVLFAANEGYVDDVENDQVVRFEKALLDYLRAEHAELLQRITETGDYNDEIHAEMQKAMDAFKKNRTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS6_MYCAP
Sequence: MNKYEIMLIIDPAIDMAMANEIVESVFDKKNINKVVKLENSTLAYPINKSSKAQYVVYTLEAKSELIAEFTRRANIAKFIWRQMVINLDTEKGFQRSKKAFKHRIAKDAKVANKGTGVKQLIENLEKTMSHKAKPSFKKEVKKSN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: UNG_ENTFA
Sequence: MKEIIHNSWQNILSAEFEKPYYQELREFLKKEYQTQTIYPDMYHLFSALELTPFEEVKVVILGQDPYHGPNQAHGLSFSVQPGVKVPPSLANIYKELQADLGYQPVNHGFLESWAKQGVLLLNTVLTVRAGQAYSHRGKGWEQLTDVIIEKLNEREKPVVFILWGRPAQEKIKMIDTTRHVIIKSPHPSPLSAHRGFFGSRPFSQANAALERLGETPIDWQLPETV
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRF_SHEEP
Sequence: MRLPLLVSVGVLLVALLPSPPCRALLSRGPIPGARQASQHPQPLSFFQPLPQPQEPQALPTLLRVGEEYFLRLGNLDETRAAPLSPAASPLASRSSSRLSPDKVAANFFRALLQPRRPLDSPAGPAKRGTENALGSRQEAPAARKRRSQEPPISLDLTFHLLREVLEMTKADQLAQQAHSNRKLLDIAGK
What is the function of this protein?
Hormone regulating the release of corticotropin from pituitary gland (PubMed:6267699, PubMed:6273874).  Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
What are the official names of this protein?
Corticoliberin, Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone, Endorpholiberin.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Protein: ARGB_NITWN
Sequence: MPDDSRISPLDQARILSEALPHMQRYDEETIVIKYGGHAMGSENVARQFASDIVLLEQTAINPVVVHGGGPQIAAMLQRLGIKSEFAAGLRITDAATIEIVEMVLAGSINKQLVGYINEAGGKAVGLCGKDGNMVTAAKATRMLADPDSNIEKVVDLGFVGEPEKVDLTLLNQLIGHELIPVLAPLATSKGGQTFNVNADIFAGAVAGALKAKRLLLLTDVPGVLDKSKKLIPELSISDARKLIADGTISGGMIPKVETCIYALEQGVSGVVIIDGKTPHAVLLELFTNQGTGTLIHK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SATC1_SORC5
Sequence: MASGEGFVVWFTGLSGSGKSTLAAMLAAELPRRGVHVESLDGDVVRTHLSKGLGFSREDRDTNIRRIGFVARLVARSGACAITAAISPYREIRDEQRRAIGRFCEVYCECPLDVLERRDIKGLYARARAGEIKGFTGVDDPYEPPRSPEVIVHTDRESPREGLARILAKLEELGYVRPMAQPAEPARAGLAPPHGGELVDRFVRGDARQRLLERVAGLPRVRLDERGASDLELIGNGAYSPLKGFMTSRDYLRVVRERRLESGLVWSIPITLAVPGEDAARLSLGSEVALASPDGRVVGVLELVDRWTPDKEVEARNVYGATDEGHPGVAYLRSSGDVYLGGEVWLIERPLSPQFPEYPRDPAATRAAFEARGWRRVVGFQTRNPIHRAHEHITKCALEITDGLLLHPLVGATKAGDIPADVRMRCYELLLEKYYPADRVVLGLYPAAMRYAGPREAIFHALVRKNYGCSHFIVGRDHAGVGRFYGTYDAQRAFDDFLPSELGIEPLKFEEAFWSTVVGGMATDKTAPGGPETRITLSGTQVRELLRAGKLPPPEFSRPEVAQILLSATQGRGHDQAA
What are the official names of this protein?
Probable bifunctional SAT/APS kinase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the sulfate adenylyltransferase family.
Protein: UPP_SULAC
Sequence: MTLYVLSKPILLHFLTQLRSKNIDQISFRKNLVKLGRIIGYEIVNTLDYESIDVETPLGTKAKGIYIYDLENILIISILRAATPFVEGLLKALPTARLGVIAASRKEKEVQVGYPEDIPVDVYYMKIPQVSHKDTVIIADPMIATGSTMRKAIKSIVNSQPKRIYIASVIISEYGLKRLMEEFPFVDIFTISVDPEIDNRGFILPGLGDAGDRAFG
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: LPTE_ECO45
Sequence: MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPNGPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIMTVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLPSIRAADIRSDEEQTSTTTDTPATPARVSTTLGN
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PURA_SACEN
Sequence: MPAIVLIGAQWGDEGKGKATDLLGEQAQWVVRYQGGNNAGHTVVLPDGQDFALHLIPSGILTPGVTNVIGNGVVVDPGVLLDELAGLEARDIDTNRLLISADAHLIMPYHVAIDRVTERYLGKKQIGTTGRGIGPCYQDKIARVGVRVQDVLDEKILRQKVEAALDIKNQILVKVYNRRGLDVDEVVDTVLGQAEKFAGRIADTKLLINQALDRGETVLLEGSQGTLLDVDHGTYPFVTSSNPTSGGACAGSGIGPTRINGVVGILKAYTTRVGAGPFPTELTDDAGENLRKAGGEFGVTTGRSRRTGWFDAVIARYATRVNGITDYFLTKLDVLTGLQTIPVCVAYDVDGERVTEMPMTQTGVHHAVPVYEELPGWWEDVSGARSFEELPANAQAYVKRLEELSGARISAIGVGPGRDQTIVRHTMA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_RENSM
Sequence: MRTYTPKPGDINRQWHVIDATDVVLGRLASQTATLLRGKHKPTFAPHMDMGDFVIIINAEKVALTGAKLEQKRAYRHSGYPGGLSSVNYAELLEKNPVRAVEKAIKGMLPKTSLAAQQLSKLKVYRGAEHPHAAQQPKTFEITQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MEND_CHLCH
Sequence: MNNRQITTLWSTLLVEALIRQGVDFFCISPGSRSTPLTIAAARNPRARTKLFADERSAAFFALGYARATEMVAPLICTSGTAVANYFPAVVEASMDFQPMLIISADRPFELLECGANQTIRQEHIFGSYTRWSMQLPTPSVEVPLTSLLSTVEYAVAKALNTPAGVVHLNQPFREPFEPESVAANNHAWWQSAQQWLASKAAHTTTTVEKKHPNNASITLLRQHLTTAKQPLLIAGSMRCKDDAEAVAALANNLKIPLYADFSSGLRMKSNLPPLQLLMQSPAWRAAFHPDVVLHFGGNVVAKHLATALREWQPAHYMVVREEPMRFSPDHNVTHRLEASIAATAHALHNSRSTPLWRESEADHFFAQAAQELEGDVVADQPITEISAARLISRHIGTEQALFVSNSMAVRDMDMYAASLHEAGIPTAINRGASGIDGILSTAAGFACGHGKSTTLLIGDIAFLHDLNALSLLGSLTVPLQIVLLNNNGGGIFSFLPIAACDDLFETYFATPQHYSIPLAAETFGLHYANPTTNSEFVAAYHQAQQSPQSTIIEVKSSRTNNLQHHRLLNARLQAIAAKLFNG
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RL16_VIBCH
Sequence: MLQPKRTKFRKVQTGRNRGLAKGTEVSFGTFGLKAVGRGRLTARQIEAARRAMTRHIKRQGKIWIRVFPDKPITEKPLEVRQGKGKGNVEYWVAQIQPGKVMYEVDGVPEELAREAFRLAARKLPFKTTFVTKQVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RLME_BUCAI
Sequence: MIVQKKKHRSNRWLLEHFQDQYVKAAKKNNIRSRAWFKLEQLDKNNKIFKIGMNVIDLGAAPGSWSQYASNRIGKKGRIIACDILPIRPITGVDIFQGDFRNKKTLNLMLNTFSNITFHLVMSDMAPNITGNFSIDMPRIIELCKLALKISEHVLSKNGIFLLKSFQGEGFNELYKEIKMLFKKIKICKPKTSRTRSREIFILATR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_ALCBS
Sequence: MSEVSLQAVKDYLLDLQDRICDALGAEDGAATFREDSWEREQGGGGRSRVLENGAVIEKGGVNFSHVFGEQLPPSATEARPELAGRSFQAMGVSLVIHPKNPYVPTSHANVRFFVAEKEGEAPVWWFGGGFDLTPYYGFEEDVVHWHQTAKVACQPFGKEIYPEFKTWCDDYFYLKHRNEPRGVGGLFFDDLNRFDFDTSFALMRSIGDAYVPAYQPILARRKDHEFGDRERQFQLYRRGRYVEFNLVYDRGTIFGLQSGGRTESILMSLPPLVRWDYDYHPEPNSAESELYHKFLIHREWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIRB8_BRUSU
Sequence: MFGRKQSPQKSVKNGQGNAPSVYDEALNWEAAHVRLVEKSERRAWKIAGAFGTITVLLGIGIAGMLPLKQHVPYLVRVNAQTGAPDILTSLDEKSVSYDTVMDKYWLSQYVIARETYDWYTLQKDYETVGMLSSPSEGQSYASQFQGDKALDKQYGSNVRTSVTIVSIVPNGKGIGTVRFAKTTKRTNETGDGETTHWIATIGYQYVNPSLMSESARLTNPLGFNVTSYRVDPEMGVVQ
What is the function of this protein?
The VirB system could be required for the establishment of the replication niche in the host.
What are the official names of this protein?
Type IV secretion system protein virB8.
What is the protein family that this protein belongs to?
Belongs to the virB8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ASAH1_HUMAN
Sequence: MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
What is the function of this protein?
May directly regulate steroidogenesis by binding the nuclear receptor NR5A1 and negatively regulating its transcriptional activity.
What are the official names of this protein?
Acid ceramidase, AC, ACDase, Acid CDase, Acylsphingosine deacylase, N-acylethanolamine hydrolase ASAH1, N-acylsphingosine amidohydrolase, Putative 32 kDa heart protein, PHP32.
What is the protein family that this protein belongs to?
Belongs to the acid ceramidase family.
What are the subcellular locations of this protein?
Lysosome. Secreted. Note=Secretion is extremely low and localization to lysosomes is mannose-6-phosphate receptor-dependent. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Cytoplasm. Note=A localization to the nucleus and the cytoplasm has also been reported for ASAH1, most probably for isoforms devoid of a signal peptide.
Protein: LEC3_AXIPO
Sequence: ASPXENYQXYVILNL
What is the function of this protein?
Possesses D-galactose binding specificity.
What are the official names of this protein?
Lectin-3, Lectin III.