PharMolix/UniProtQA huggingface dataset:
Protein: NFRA_STAAB
Sequence: MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFIFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
What is the function of this protein?
Reduces FMN, organic nitro compounds and disulfide DTNB.  Involved in maintenance of the cellular redox state and the disulfide stress response (By similarity).
What are the official names of this protein?
NADPH-dependent oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the flavin oxidoreductase frp family.
Protein: URK_UREPA
Sequence: MNTKSPILILIAGASGSGKTTFANEIIARIPKNTTSVVICQDSYYISNSQLNKKERRLINYDHPSSFEWELMREQLSDIKKRKKIKVPIYDYKTEIRLDKTIDISDVDVIVLEGIYAIYDDVINQIADLKIFIETPKDECLIRRILRDVNERNRSFESVITQWRSTVSPMYDQFVEPSKKNANVSVLWNEHNRVALHLIHKWINNIH
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_SHESA
Sequence: MHFHERFDVIVVGGGHAGTEAALAAARMGSKTLLLTHNLDTLGQMSCNPAIGGIGKGHLVKEIDALGGAMAIATDYAGIQFRTLNSSKGPAVRATRAQADRALYRQKIQNILQNQANLRIFQQAVDDLVVDNDRVVGVVTQMGLAFEAPAVVLTAGTFLSGKIHIGLENYSGGRAGDPPSIALAHRLRELPIRVGRLKTGTPPRIDANTIDFTQMTEQKGDTPLPVMSFMGDVSHHPKQISCWITHTNEKTHDIIRGGLDRSPMYSGVIEGIGPRYCPSIEDKIHRFSDKSSHQIFIEPEGLNTNEIYPNGISTSLPFDVQLNLVRSIQGMENAEIVRPGYAIEYDYFDPRDLKNSLETKTINGLFFAGQINGTTGYEEAGAQGLLAGMNAALQVQGKEAWCPRRDEAYIGVLVDDLSTLGTKEPYRMFTSRAEYRLLLREDNADLRLTAKGRELGLVDDARWASFSEKMESIELELQRLRSQWIHPNSPLVPVLNPHLNTPISREASFEELLRRPEMDYSKLMQIEGFGPGLADPLAAEQVQIQVKYSGYIQRQQEEINKAVRNENTGLPLNLDYKEVPGLSNEVIAKLNSHKPETIGQASRISGITPAAISILLVHLKKRGLLRKSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_ALISL
Sequence: MSSSLWLQCLQRLQEELPSAEFSMWVRPLQAELNDNTLTLFAPNRFVLDWVRDKYLNSINSLLNEFCGGDIPTLRFEVGSKPISAPPRPQRTAADVAAATSAPAQMQARQSLHKPWESRGPEPVDDLNHRSNVNPKHKFTNFVEGKSNQLGLAAARQVSDNPGTAYNPLFLYGGTGLGKTHLLQAVGNAILERKPNAKVVYMHSERFVQDMVKALQNNAIEEFKCYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVVANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADLLSKRRSRSVARPRQLAMALSKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMN8_HUMAN
Sequence: MAPRGFSCLLLSTSEIDLPVKRRA
What is the function of this protein?
Plays a role as a neuroprotective and antiapoptotic factor.
What are the official names of this protein?
Humanin-like 8, HN8, MT-RNR2-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the humanin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: YFAE_ECOLI
Sequence: MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
What are the official names of this protein?
Uncharacterized ferredoxin-like protein YfaE.
Protein: HIS4_RHILO
Sequence: MILFPAIDLKDGQCVRLKHGDMATATIYNDDPAAQAKAFEDQGFEWLHVVDLNGAFKGQSVNSAAVGAILKATKNPVQLGGGIRTLAQIEDWLDRGLARVILGTVAVRDPDLVRQACKAFPGKVAVGIDAKGGKVAVEGWAEASSLGVVELARKFEGAGVAAIIYTDIDRDGVLTGINWDATIDLAEAVSIPVIASGGLASIADIVRMTMPDAQKLEGAISGRALYDGRIDPAEALAILQGRPEAKS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF21_SCHPO
Sequence: MSYANYRYMKARAKRWRPENLDGIQTSDEHLINLFAKILSKHVPEIGKFDPNKDVESYISKLDQHFTEYPSLFPNEHTKRQYTLNHLEELEQQFAERMFSENGSLTWQELLRQTGKVQGSNKGDRLTKTFEGFRNQLDKVQFIRKLMSKANVDDFHTRLFILWMLPYSLRKLKERNYWKSEISEIYDFLEDKRTASYGKTHKRFQLQNKNLGKESLSKKNNTTNSRNLRKTNVSRIEYSSNKFLNHTRKRYEMVLQAELPDFKCSIPCLIDTGAQANIITEETVRAHKLPTRPWSKSVIYGGVYPNKINRKTIKLNISLNGISIKTEFLVVKKFSHPAAISFTTLYDNNIEISSSKHTLSQMNKVSNIVKEPELPDIYKEFKDITAETNTEKLPKPIKGLEFEVELTQENYRLPIRNYPLPPGKMQAMNDEINQGLKSGIIRESKAINACPVMFVPKKEGTLRMVVDYKPLNKYVKPNIYPLPLIEQLLAKIQGSTIFTKLDLKSAYHLIRVRKGDEHKLAFRCPRGVFEYLVMPYGISTAPAHFQYFINTILGEAKESHVVCYMDDILIHSKSESEHVKHVKDVLQKLKNANLIINQAKCEFHQSQVKFIGYHISEKGFTPCQENIDKVLQWKQPKNRKELRQFLGSVNYLRKFIPKTSQLTHPLNNLLKKDVRWKWTPTQTQAIENIKQCLVSPPVLRHFDFSKKILLETDASDVAVGAVLSQKHDDDKYYPVGYYSAKMSKAQLNYSVSDKEMLAIIKSLKHWRHYLESTIEPFKILTDHRNLIGRITNESEPENKRLARWQLFLQDFNFEINYRPGSANHIADALSRIVDETEPIPKDSEDNSINFVNQISITDDFKNQVVTEYTNDTKLLNLLNNEDKRVEENIQLKDGLLINSKDQILLPNDTQLTRTIIKKYHEEGKLIHPGIELLTNIILRRFTWKGIRKQIQEYVQNCHTCQINKSRNHKPYGPLQPIPPSERPWESLSMDFITALPESSGYNALFVVVDRFSKMAILVPCTKSITAEQTARMFDQRVIAYFGNPKEIIADNDHIFTSQTWKDFAHKYNFVMKFSLPYRPQTDGQTERTNQTVEKLLRCVCSTHPNTWVDHISLVQQSYNNAIHSATQMTPFEIVHRYSPALSPLELPSFSDKTDENSQETIQVFQTVKEHLNTNNIKMKKYFDMKIQEIEEFQPGDLVMVKRTKTGFLHKSNKLAPSFAGPFYVLQKSGPNNYELDLPDSIKHMFSSTFHVSHLEKYRHNSELNYATIDESDIGTILHILEHKNREQVLYLNVKYISNLNPSTIMSGWTTLATALQADKAIVNDYIKNNNLNI
What are the official names of this protein?
Transposon Tf2-1 polyprotein, Retrotransposable element Tf2 155 kDa protein.
Protein: TX602_LYCSI
Sequence: MKLLLFTALVLVVISLIEVEAENERACIPLEKECTKTPGNCCSGLKCNCYRRFEQGVAKGIQCWCIEKDVTYKGV
What are the official names of this protein?
U6-lycotoxin-Ls1c, Toxin-like structure LSTX-F2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 06 (U6-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSL58_DICDI
Sequence: MTILSAITSISRPNKSSKSVISSNGGSSLSMGSNSVSCFNACGGGSSYSYSSSYSGSGLDYSYKANYSSSTGYNSSVIIASSTCHCS
What are the official names of this protein?
HssA/B-like protein 58.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: HCAB_ECO8A
Sequence: MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVASLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPAETLETGFHELFNVNVLGYLLGAKACAPALISSEGSMIFTLSNAAWYPGGGGPLYTASKHAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAILPLQFFPQPADFTGPYVMLASRRNNRALSGVMINADAGLAIRGIRHVAAGLDL
What is the function of this protein?
Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively.
What are the official names of this protein?
3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase, 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase, 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase, CI-dihydrodiol dehydrogenase, Cis-3-(2-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol dehydrogenase, Cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol dehydrogenase, PP-dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: DSG1C_MOUSE
Sequence: MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
What are the official names of this protein?
Desmoglein-1-gamma, Dsg1-gamma, Desmoglein-6.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: SMC5_MOUSE
Sequence: MATPSGKAAPPNPQVSKRSLPRDASSEVPSKRKNSNPLPTLPRPSGTFVEGSIVRIAMENFLTYDICEVSPGPHLNMIIGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSKGLVEIELFRTSGNLIITREIDVIKNQSFWFINKKPVTQKIVEEQVAALNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSVGPPEMHRYHCELKNFREKEKQLETSCKEKTEYLEKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEGVKLIRDRVKEEVRKLKEGQIPMTRRIEEIDRQRHTLEVRIKEKSTDIKEASQKCKQRQDLIERKDRQIKELQQALTVKQNEELDRQKRISNTRKMIEDLQSELKTAENCENLQPQIDTVTNDLRRVQEEKALCEGEIIDKQREKEMLEKQRRSVSDHITRFDNLMNQKEDKLRQRYRDTYDAVLWLRNNRDRFKQRVCEPIMLTINMKDNKNAKYVENHISSNDLRAFVFESQEDMEIFLREVRDNKKLRVNAVIAPKISYADKAPSRSLNDLKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTERTRERIERVIQETRLKQIYTAEEKYVLKTSVYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEMNRQLEAVDSGLAALRDTNRHLELKDNELRLKKKELLERKTRKRQLEQKISSKLASIRLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTGLVKICTSFQIQKVDLILQNTTVISEKNKLEADYMASSSQLRVTEQQFIELDDNRQRLLQKCKELMKKARQVCNLSADQAVPQEFQTQVPTIPNGHSSSPPMAFQDLPNTLDEIDALLTEERSRASCFTGLNPSVVEEYSKREVEIQQLTEELQGKKVELDEYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEPNRWNLKAFQRRRRRITFTQPQ
What is the function of this protein?
Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination.  The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.  The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.  Required for sister chromatid cohesion during prometaphase and mitotic progression; the function seems to be independent of SMC6 (By similarity).
What are the official names of this protein?
Structural maintenance of chromosomes protein 5, SMC protein 5, SMC-5, mSMC5, Protein expressed in male leptotene and zygotene spermatocytes 453, MLZ-453.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC5 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Nucleus, PML body. Chromosome, telomere. Note=Colocalizes with SMC6 on the X-Y chromosome pair within the sex vesicle during late pachytene/diplotene (PubMed:11408570). Associates with chromatin. Localizes to PML nuclear bodies in ALT cell lines. Accumulates with RAD18 and the SLF1-SLF2 complex at replication-coupled DNA interstrand repair and DNA double- strand breaks (DSBs) sites on chromatin in a ubiquitin-dependent manner.
Protein: NADD_BACFN
Sequence: MAKTKTGIFSGSFNPIHIGHLALANYLCEFEGLDEVWFMVTPHNPFKNQADLWPDELRLQLVQLAIEGYPRFRVSDFEFHLPRPSYTIHTLNRLKQEYPEREFQLIIGSDNWMVFDRWFESERIVSENKILVYPRPGFSVDKSQLPPNVHVADSPIFEISSTFIREALATGKDIRYFLHPAVYKRIIQQTDSIDSSHSCHT
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: CCME_VIBVU
Sequence: MNPRRQKRLGIILAILIGVSATIGLMIYALNQNMDLFYTPTELVNGKDDGTKPEVGQRLRIGGMVVMGSVRRDPESLKVRFDLADVGPKVTIEYEGILPDLFREGQGIVAQGVLKDATTVEAFEVLAKHDEEYMPPEIAEAMKKTHAPLQYSEEQKQGSGQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RL3_DEHMB
Sequence: MIQGIIGKKIGMTQIFQEDGKAQPVTLVEAGPCVVVQVKTEKQDGYEAVQLGYGKAKHITSAVKGQCRGFGEFKVLREVDVDDIAAVSVGDQITVSDFKDGEKIDASGVSRGRGFSGVVKRWHFAGGPKTHGQSDRHRAPGSIGSTTTPGRIYKGKHMAGHMGNEAVTIRNLVVLKTDAEKNLLMVKGAIPGGKNTIILIKKTGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: FCSK_MOUSE
Sequence: MEQSEGVNWTVIILTCQYKDSVQVFQRELEVRQRREQIPAGTMLLAVEDPQTRVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPQAPVEALVCNLDCLLDIMTHRLGPGSPPGVWVCSTDMLLSVPPNPGISWDGFRGARVIAFPGSLAYALNHGVYLTDSQGLVLDIYYQGTKAEIQRCVGPDGLVPLVSGVVFFSVETAEHLLATHVSPPLDACTYMGLDSGAQPVQLSLFFDILLCMARNMSRENFLAGRPPELGQGDMDVASYLKGARAQLWRELRDQPLTMVYVPDGGYSYMTTDATEFLHRLTMPGVAVAQIVHSQVEEPQLLEATCSVVSCLLEGPVHLGPRSVLQHCHLRGPIRIGAGCFVSGLDTAHSEALHGLELHDVILQGHHVRLHGSLSRVFTLAGRLDSWERQGAGMYLNMSWNEFFKKTGIRDWDLWDPDTPPSDRCLLTARLFPVLHPTRALGPQDVLWMLHPRKHRGEALRAWRASWRLSWEQLQPCVDRAATLDFRRDLFFCQALQKARHVLEARQDLCLRPLIRAAVGEGCSGPLLATLDKVAAGAEDPGVAARALACVADVLGCMAEGRGGLRSGPAANPEWIQPFSYLECGDLMRGVEALAQEREKWLTRPALLVRAARHYEGAEQILIRQAVMTARHFVSTQPVELPAPGQWVVTECPARVDFSGGWSDTPPIAYELGGAVLGLAVRVDGRRPIGAKARRIPEPELWLAVGPRQDEMTMRIVCRSLDDLRDYCQPHAPGALLKAAFICAGIVHLHSELPLLEQLLHSFNGGFELHTWSELPHGSGLGTSSILAGAALAALQRAAGRAVGTEALIHAVLHLEQVLTTGGGWQDQVSGLMPGIKVGRSRAQLPLKVEVEEITVPEGFVQKINDHLLLVYTGKTRLARNLLQDVLRNWYARLPVVVQNARRLVRQTEKCAEAFRQGNLPLLGQYLTSYWEQKKLMAPGCEPLAVQRMMDVLAPYAYGQSLAGAGGGGFLYLLTKEPRQKETLEAVLAKAEGLGNYSVHLVEVDPQGLSLQLLGHDTRLCGAGPSEVGTT
What is the function of this protein?
Has very weak fucokinase activity.
What are the official names of this protein?
L-fucose kinase, Fucokinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family.
Protein: DNAA_NAUPA
Sequence: MSIFTKIKKSLKSENLVNYNKFIKNLEFDEKNSTSTHLIIKAPNIFIANFVKRKYLNKISELYEKETGIKPKIDIVTKEISHRPLTIEEIIEPTTPSVLIPEYTFESFIVGPSNQFAYTAAKSVAENPGKNYNPLFIYGGVGLGKTHLLQAIGNYLKSSLNVLYVTSEQFMNEFTENIRMKTPERFHEKYRNCDVLLIDDVQFFAGKERTQEEFFHTFNELYNQKKQICLTADRPPKKLYDLVDRLRSRFEAGLIVDIQPPELETKIEIIRKKCELNGIYLPEEIIEYIATKLDSNIREIEGMITKINAMSKILGISEITLDFAKQALKEHIKDKKEVITLEDIIKLIAKEFNIKPSEIVSKSRNKNIVAARRCAIYLAREFTKESTPIIAKYFGLRDHSAVSHAIKSFNKKLKEDSEFRIKIEELKNKIQIKKSE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOVO_BUGCA
Sequence: TATVDCSDYPKPACTLEYMPFCGSDSKTYSNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: CREC_ASPFU
Sequence: MAVPVVETNNILSHPEGGCPLQVGEGTYELKDDLHLATPPPHPSEAPIINPNPLATVPTPPTSGVKVSLVCVSPRSRTPSFISKQIVTAPPFGDGNPALVPAPVKDGLKRRKPKNNIIKSSSSFVSRVITHEVATKRLSERSPEGLFAFANINRAFQWLDLSSKQKEDPLAKILFTKAHMLCHDINEVTKSPSHIDVVMGSSAGDIIWYEPISQKYARINKNGVVCNSPVTHIKWIPGSENLFMASHANGQLVVYDKEKEDALFTPEIQDQSAEAVKASSTQPLQVLKSVNSRNQKTNPVALWKLANQRISHFAFSPDQRHLAVVLEDGSLRVMDYLKEDYYGGLICVCWSPDGKYIVTGGQDDLVTIWSFPERKIVARCQGHNSWVSAVAFDPWQCDERTYRFGSVGDDCRLLLWDFSVGMLHRPKVHQTSARQRTSMVAGSSQYGNRHRADSVGNRMRSDSQRTANTYESCDQAVRHPVEPRARTALLPPIMSKVVGTDPICWLGFQEDCIMTSSLEGHIRTWDRPREGINDKYNDQSSSTAVSASAAGSGSISGLAESTMGSL
What is the function of this protein?
Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression.  CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity).
What are the official names of this protein?
Probable catabolite repression protein creC.
What is the protein family that this protein belongs to?
Belongs to the WD repeat creC family.
Protein: SELU_PSYIN
Sequence: MQQSDLQEQQLYRSLFLLKTPLIDLRAPVEFAQGAFPESCNLPLMTDNEREQVGTCYKKEGQAAAITLGHQLVASDIQNRIRKWAQFKEENPTAWLYCFRGGLRSRLSAQFLKDHGVDINIVPGGYKALRRYLINVIDQASEKKLMIVGGNTGCGKTLLIQALDNGLDIEGRANHRGSSFGKQVTEQPRQISYENQLAVDILHISQHASSLVIEDESKAVGALYVPERLFAGMTRAPMVVVNDPLEIRLQRLCYEYCTLMTEKFNLALGAEQGWQAYEKYLQNGLYGIRKRLGTEKFKVMNTVLEAALKQQKNTGSVEGHLNWIASILRDYYDPMYQYQLEKKADRVQFRGTFQEVKEWLTVNTK
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: VP2_CAVC1
Sequence: MHGNGGQPAAGGSESALSREGQPGPSGAAQGQVISNERSPRRYSTRTINGVQATNKFTAVGNPSLQRDPDWYRWNYNHSIAVWLRECSRSHAKICNCGQFRKHWFQECAGLEDRSTQASLEEAILRPLRVQGKRAKRKLDYHYSQPTPNRKKVYKTVRWQDELADREADFTPSEEDGGTTSSDFDEDINFDIGGDSGIVDELLGRPFTTPAPVRIV
What is the function of this protein?
May act as a scaffold protein in virion assembly.  May also play a role in intracellular signaling during viral replication.
What are the official names of this protein?
Dual specificity protein phosphatase VP2.
What is the protein family that this protein belongs to?
Belongs to the gyrovirus protein VP2 family.
Protein: GRPE_BACC7
Sequence: MEERNEQVVEEVKEEVKEAQVEEAVTSEDSEETVEEKSEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRRVQMDKQAAEKYRAQSLVSDILPALDNFERAMQVEATDEQMKSLLQGMEMVYRQLLEAMTKEGVEAIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_HAEIN
Sequence: MSFDKQNLIWIDLEMTGLDPEKERIIEIATIVTDKNLNILAEGPVLAVHQSDELLNKMNDWCQKTHSENGLIERIKASKLTERAAELQTLDFLKKWVPKGASPICGNSIAQDKRFLVKYMPDLADYFHYRHLDVSTLKELAARWKPEILEGFKKENTHLALDDIRESIKELAYYREHFMKLD
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_LACLM
Sequence: MAVSVQDLLDKIHFHVIYSTETALQKEITTSEIMRPGLEMAGYFDYFTPERIQLFGMKEWSYMMTVVGDNRYDLLKKVMAKETPVVIVARNLEIPSEMVAAAKKADIVLLQSREATSRLNSVLTSFLDERLAERTTVHGVLMDIFGVGVLIQGASGIGKSETGLELVKRGHRLVADDRVDVFQRDAFTLSGEPAEILRNMIEIRGVGIIDVMSLFGAGAVKDSTDIDMAIYLEYYDKEKAFDRLGNAPTIVEFSDVEVPQTRIPVKTGRNVSVIVEAAVMNFRAKQMGFDATKTFEDRLTDLISHNKESQ
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: UBIG_ACIAD
Sequence: MSQLNVDPQEIAKFEALAAKWWDQHSEFRPLHQINPLRLNWIDEHAGGLAGKKVLDVGCGGGILAESMARRGADVLGIDMGEAPLNVARLHAEQEQVANIEYRQIPVEELAQEQAGQYDIVTCMEMMEHVPDPASIIKACQTLVKPGGHVFFSTINRNPKSYLFAIIGAEYVLRLLPKGTHDYHKFIRPSEMAHDIREAGLKLKDMTGLHYNPLTKHYWLAPNVDVNYMVHTLKEGQS
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: Y1904_STRE4
Sequence: MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELNTALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSNVNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDDVEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKLVDALEADDDVQKVYHNVADV
What are the official names of this protein?
Probable transcriptional regulatory protein SEQ_1904.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.