PharMolix/UniProtQA huggingface dataset:
Protein: CPIN1_HUMAN
Sequence: MADFGISAGQFVAVVWDKSSPVEALKGLVDKLQALTGNEGRVSVENIKQLLQSAHKESSFDIILSGLVPGSTTLHSAEILAEIARILRPGGCLFLKEPVETAVDNNSKVKTASKLCSALTLSGLVEVKELQREPLTPEEVQSVREHLGHESDNLLFVQITGKKPNFEVGSSRQLKLSITKKSSPSVKPAVDPAAAKLWTLSANDMEDDSMDLIDSDELLDPEDLKKPDPASLRAASCGEGKKRKACKNCTCGLAEELEKEKSREQMSSQPKSACGNCYLGDAFRCASCPYLGMPAFKPGEKVLLSDSNLHDA
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2.  Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 (PubMed:23596212).  NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit (By similarity).  Has anti-apoptotic effects in the cell.  Involved in negative control of cell death upon cytokine withdrawal.  Promotes development of hematopoietic cells (By similarity).
What are the official names of this protein?
Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: XRN2_DROME
Sequence: MGVPAFFRWLSRKYPSVIIECNENKQVDADTGRNIYEDPTLPNPNGIEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFECIDRLFGIVRPRKLLYMAIDGVAPRAKMNQQRSRRFRAAKETTEKRLEIARIREELLSRGCKLPPEKEKGEHFDSNCITPGTPFMDRLSKCLHYFVHDRQNNNPAWKGIKVILSDANVPGEGEHKIMDYIRKQRAQPDHDPNTQHVLCGADADLIMLGLATHEPNFTIIREEFLPNKPRPCDICNGFGHEMDKCVGLGATAPTSANFKPDVPIGAEVKFIFVRLSVLREYLKQTLEMPNLPFEYSFERALDDWVFMCFFVGNDFLPHLPSLEIREGAVDRLVELYKKCVYKTRGYLTDSGDVNLDRVQLIMTDLGNAEDQIFKSRQRREEQFKARDKARKRQERNQDHGSLNQSAFGASAVGPNSQQRSVGNYKEEAAALRNRKRTSDMANLDDEDEEENNDEVRLWEDGFKDRYYESKFDVAPGNQQFRYAVALQYVRGLCWVLKYYYQGCASWNWYFPYHYAPFASDFVNIQGLSTMFEKGTKPFNPLEQLMGVFPAASSSHVPEPWAKLMSDPESPIIDFYPEDFKIDLNGKKFAWQGVALLPFVDEKRLFKALVPYYDQLTGEEVKRNKRGDNYLYISNQSPHYKKVKKISEKDDESVCKAISFDGMRGTLGKTELNTAISGVLKSPISGLSDINDNITVTTTFRDPEYDEDYIFEAKRLENAVDPPQVLPNEQSGNKHRPVIGFNSHLTRAYVPDSGHRMLNAGIRNQQGGGGNGGGGGGYGQGGGYGQGIGGNQGQSYQNNSRNYNYNYNNNYNQHQGGGYQNNYNNRQQQQYGHNQRFNQDNSNQQQRNFNNYNGPRNNNYQQQGGSRQQNQNYRRF
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity.  May promote the termination of transcription by RNA polymerase II (By similarity).
What are the official names of this protein?
5'-3' exoribonuclease 2 homolog, Ribonucleic acid-trafficking protein 1, dRAT1.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SFH7_ARATH
Sequence: MADTKQDMENSEDGRKLVKMSSLKQKAISASNRFKNSFKKKTRRTSSKIVSVANTDDINGDDYLSVEAFRQVLVLDDLLPPKHDDLHMMLRFLRARKFDKEKAKQMWSDMLQWRMDFGVDTIIEDFEFEEIDQVLKHYPQGYHGVDKEGRPVYIERLGQIDANKLLQATTMDRYEKYHVKEFEKMFKIKFPSCSAAAKKHIDQSTTIFDVQGVGLKNFNKSARELLQRLLKIDNDNYPETLNRMFIINAGPGFRLLWAPIKKFLDPKTTSKIHVLGNKYQPKLLEAIDASELPYFFGGLCTCADKGGCLRSDKGPWNDPELLKIARNPEARFSTISEEDYLLVEEGTSMSMVFEPLERNKMKTIEENVSEKHIDAVDKFMALSLPPKPHLKTLRKGKEPQKKDDSFLVGGVIAFVMGIVAMLRLSKAVPRKLTDVALLTNSVYYEEAKMSKPNQDEVSAPPVSSSEYVIMVKRMAELEEKYKSLDSKSADEALEKDDKLQAALNRVQVLEHELSETKKALDETMVNQQGILAYIEKKNKKKRMFFRF
What is the function of this protein?
Required for transport of secretory proteins from the Golgi complex.  Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity).
What are the official names of this protein?
Phosphatidylinositol/phosphatidylcholine transfer protein SFH7, Protein SEC FOURTEEN HOMOLOGS 7, AtSFH7.
What is the protein family that this protein belongs to?
Belongs to the SFH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Protein: ADHX_ARATH
Sequence: MATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEGLFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATGVGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASGQEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKAFDLLHEGTCLRCVLDTSK
What is the function of this protein?
Plays a central role in formaldehyde detoxification.
What are the official names of this protein?
Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, S-(hydroxymethyl)glutathione dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_METS3
Sequence: MKRTALKIGYIGTNFHGFQRQPDLRTVEEELIYHLRKLGYIDDLKKSRFRIAGRTDAGVHSLGNVISFQSEKEVRVNEINNSLPDDIQILAKAPVRFGFKPRYAEMRQYRYVLFRSDLDLYKLNEVAEIFKGTHNFTNFTKRFQKTTTRTIDDIKITKANLNDYHKKEFPNLHDTLSPVFVDIYGESFLWNMVRKMMRVFVDVAIGKLSLEKVEELLNPAENDPRANIKVLDPDYLILMDIKYDGVKFVYDDYACERFKRNLVDSLGDLQRKYAIRESMIKSLEDLERIN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LG1_MAIZE
Sequence: MMNLSAAANGRDEFPPYVVPSNAAAPPPSLLPTMEQQQESSIHREHHQLLGYNLEANSLALLPPSNAAAAHHHTTFAGGHSPHDILHFYTPPPSAASHYLAAAAGNPYSHLVSAPGTTFHQTSSSYYPPAAAAQAAPEYYFPTLVSSAEENMASFAATQLGLNLGYRTYFPPRGGYTYGHHPPRCQAEGCKADLSSAKRYHRRHKVCEHHSKAPVVVTAGGLHQRFCQQCSRFHLLDEFDDAKKSCRKRLADHNRRRRKSKPSDADAGDKKRAHANKAAAAKDKAESSSKNMDIGDGLGAQILGSALLSKEQDQTMDLGEVVKEAVDPKGKASMQQHYGFPFHSSSAGSCFPQTQAVSSDTTSNIGQVQEPSLGFHHQHHQHSNILQLGQAMFDLDFDH
What is the function of this protein?
Involved in the formation of ligules and auricles during leaf organogenesis.
What are the official names of this protein?
Protein LIGULELESS 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: U17PE_MOUSE
Sequence: MVVSLSFPEETGGENLPSAPLEDSSKFFEEVFGDMVFARSFPEADPALSSPDAPELHQDEAQVVEELTTNGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKMCAMEAHVTQSLLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSDPTPQDTSPIHDIFGGWWRSQIKCLHCQGTSHTFDPFLDVPLDISSAQSVNQALWDTGKSEELLGENAYYCGRCRQKMPASKTLHVHIAPKVLLLVLKRFSAFTGNKLDRKVSYPEFLDLKPYLSEPTGGPLPYALYAVLVHDGATSNSGHYFCCVKAGHGKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQTDLKQVSIDMPEGRVHEVLDPKYQLKKSRRKKRKKQCHCTDDAGEACENREKRAKKETSLGEGKVPQEVNHEKAGQKHGNTKLVPQEQNHQRAGQNLRNTEVELDLPVDAIVIHQPRSTANWGTDAPDKENQPWHNGDRLLTSQGLMSPGQLCSQGGR
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein E, USP17-E, Deubiquitinating enzyme 17-like protein 2, Deubiquitinating protein 3, DUB-3, Deubiquitinating protein 6, Ubiquitin carboxyl-terminal hydrolase 17-like protein 2, Ubiquitin thioesterase 17-like protein 2, Ubiquitin-specific-processing protease 17-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: GRA13_GIBZE
Sequence: MDNTIGPRVDPSIRAFDFTALFEECFLDILPWSLFLLMLLVRLKFLLNRPKIIRVDRLCLIKEALWTLYAVVKLAQLILWASIAAFTTAGTVPAAALAFVGCMGGSVLSYFEHCRSRRPSSLLGILTLLILLCDVTRVRTMWLMDQPRAISILTTAALPINILLLVFESLTKTAVANEKEASRSKEEIVGILNRSVFWWLNSLFILGRKHVLHMGNLPRVDSKVLTSYAAPKVYERWESKPQSLMLQSLQAYPMTLLRGGLCRLFTALFVTSQPLLLKRTIRWFSEPSTPVSDAEGYGLIGAYLVVYGGRAVFTALAQHQNYRLITMIRASLVSLIYDRTLTLDLVEAKESAALTLMSTDVERIGQGLQFVHEIWATPAEFGVAIFLLQREVALGSLAPVIIIIVAIVGTVLLSMKIDPHQKEWIGAIERRIGSTTDMLRNMRGVKMSGFEDALTSILQAMRVEEVNISRATKLLFIGCQVFSTATATISPVLGFTIYVLMQRAQGKPGLASSSAFTSLSLFSILSSSVYIFLTSVPAIFSGISCFARVENYLVSENITGPTDAEGQDSEASSISAEKISIIAPKIAPSDYLLVIRDGSVRWKGQEKAVLSQINLCIEQGSFCVISGSVGSGKSSLLYAILGEASLKADTFHISTTSIAYCQQSPWLPDISVKECVLNGRDWDEDLYKRVIHACALSEDLAQLSAGDHTKVGYEGGTLSGGQRQRVALARALYSRRRLLLLDDTFSALDPKTEKSVSGNLFSSSGLLRELGTTVICTTGKPGNSNKYADYTLDLNKEGEAQLRNTQKDMQDDEIEASTYSREQNGPKKQEEDANHESNQSPETSQEHELAQESVPTFSSMIFYLRSTGMGFFALSFSLSLVYSFWQNFPTIWVNLWTQHDAKHPYGDLAKYIGVYILCAVLALVTHTVVTWFVNMACNGIDGAAVRAGPTRDTPENSGTASITGRGYVVFTNKHRAPMSYFESVDIGTITNHFSQDMEKVDLEIPLTGVQALFAFTSALVQLVMLSIGTKWMAITFPFIIAILAIIQRQYLKTSRQLRLLDLEAKSPLYSHFTETLSGLATIRAFGTHKQCQSINTERLDCSQGPFYLLYCAQRWLTLVLNLVIGAMAILMMGVTIKLRGSTGAGYIGLAFVNLTTFSQSIQSLLTWWTMMEASIGAVHRVQQFEKETPQEDVLGQVTSPPHSWPKAGLIELKELSASYLSSVSPVLRNVTFTVQPGQKVGICGRTGSGKTSLILCLQRMIKINSGSILIDGLNTSHVPAKTLRERLICIPQDALIFNGTVRLNLDPQSSFTDKQLQDNLRRVELWDLISSKGGLDATMQDGLLSHGQLQLFCLSRVLQKKSPIVILDEVSSSADEESQRLISKIIREDFKDRTVISIAHRLQQIADFDIILVFSQGQLVEQGSPEDLLGRDVSLFQDLFSQQDK
What is the function of this protein?
ABC-type transporter; part of the gene cluster that mediates the biosynthesis of gramillins A and B, bicyclic lipopeptides that induce cell death in maize leaves but not in wheat leaves (PubMed:30395461).  May be involved in the secretion of gramillins (Probable).
What are the official names of this protein?
ABC-type transporter FGSG_00046, Gramillins biosynthetic cluster protein FGSG_00046.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LACA_CLOAB
Sequence: MKIAIGADTDGFELKEHLKNYLKSKGIEVIDKTPEKGINLVKSASLVAQAVMNKEADRAVAIDEYGAGSFMVGAKHKGIICAEVSDEHSAKMTSQHNSANMLAIGAGIVGKRLAEGMLDAYIAEKYAGGRHQIRVDMLNKML
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: AROK_AQUAE
Sequence: MRIYLIGFMCSGKSTVGSLLSRSLNIPFYDVDEEVQKREGLSIPQIFEKKGEAYFRKLEFEVLKDLSEKENVVISTGGGLGANEEALNFMKSRGTTVFIDIPFEVFLERCKDSKERPLLKRPLDEIKNLFEERRKIYSKADIKVKGEKPPEEVVKEILLSLEGNALGG
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_SYNR3
Sequence: MSHSVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGDETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RF1_MYCUA
Sequence: MAAPVQTIDVLLAEHADLERALADPELHSRPDEARKAGRRFARLARIVATYRKLVAAREDLETAHELAATDESFVAEAAELEARVAELDSQLTDMLAPRDPHDADDIVLEVKSGEGGEESALFAADLARMYIRYAERHGWTVTVLGETTSDLGGYRDATLAIASKGDTADGVWSRMKFEGGVHRVQRVPVTESQGRVHTSAAGVLVYPEPEEVGEVQIDESDLRIDVYRSSGKGGQGVNTTDSAVRITHLPTGIVVTCQNERSQLQNKIRAMQVLGARLQAIAEERAMADASADRASQIRTVDRSERIRTYNFPENRVTDHRIGYKSHNLDQVLDGDLDALFDALAAADKQARLQQS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LC_BUXMI
Sequence: MMLEHVLVLGAYLFSIGIYGLITSRNMVRALMCLELILNAVNINLVTFSDFFDSRQLKGDILSIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PFDA1_THEKO
Sequence: MAEDTKKLEELAYQYQLLQAQAQLLAQNLELLTLGRNEFQAVKETLEGLKNEEGEFEILVPIGAGSFLKGKIVDAKNAIVSVGAGYAVQKSLDDSIEYLEKRIKEYEEAIAKTQEALKKLEAQLGELARQAQEIQQKQAMGFSVKK
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha 1, GimC subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_AZOC5
Sequence: MILGIGSDFCDARRIEKSIERFGARFTERVFTPLERAKAERRARPAETYAKRFAAKEACAKALGTGIARGVFWRDMGVVNLPSGQPTLELTGGAAARLKEMVPEGYEPRIALSLTDEGPLSAAYVIISAELIGTPR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_ARATH
Sequence: MAALLGIVSPVTFTGKHPVNSRSRRRTVVKCSNERRILFNRIAPVYDNLNDLLSLGQHRIWKNMAVSWSGAKKGDYVLDLCCGSGDLAFLLSEKVGSTGKVMGLDFSSEQLAVAATRQSLKARSCYKCIEWIEGDAIDLPFDDCEFDAVTMGYGLRNVVDRLRAMKEMYRVLKPGSRVSILDFNKSNQSVTTFMQGWMIDNVVVPVATVYDLAKEYEYLKYSINGYLTGEELETLALEAGFSSACHYEISGGFMGNLVAMR
What is the function of this protein?
Involved in the biosynthesis of phylloquinone (vitamin K1).  Methyltransferase required for the conversion of 2-phytyl-1,4-beta-naphthoquinol to phylloquinol.
What are the official names of this protein?
2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic, Demethylphylloquinone methyltransferase, Menaquinone biosynthesis methyltransferase ubiE-like protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UBIE_CERSK
Sequence: MSDETSNTTHFGFRTVPEGEKAGMVHGVFTRVASKYDIMNDLMSGGVHRLWKDAMMDWLAPRPGQKLLDVAGGTGDISFRFLKRAPGAEATVCDMTESMLVEGRQRADAAQMADRLDWVVGDAMALPFASNTFDVYTISFGIRNVTRVQDALNEAYRVLKPGGRLMVLEFSQLPNPMMQWAYDRYSFNVIPVMGQIVANDRDSYQYLVESIRKFPDQETFADMIRKAGFGLVKYRNLSLGIAALHSGWKI
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RPN4_YEAST
Sequence: MASTELSLKRTLTDILEDELYHTNPGHSQFTSHYQNYHPNASITPYKLVNKNKENNTFTWNHSLQHQNESSAASIPPQQTYHFPIFNKYADPTLTTTTSFTTSEATANDRQINNVHLIPNEIKGASETPLQKTVNLKNIMKVSDPYVPTRNTFNYDVKISNDFFDNGDNLYGNDEEVLFYEDNYNPKMQWSLQDNSAAINNEDARAIFNNEFDSDDDDISDDEEDEIEENCLQQEQHQEEPLLSLDVTPISMFGSDQKTGRAKSSSHLFNEYSYVDSNMDSISSVVSEDLLDERGHEKIEDEDEDNDLDEDDIYDISLLKNRRKQSFVLNKNTIDFERFPSPSTSANVPSTATTGKRKPAKSSSNRSCVSNSNENGTLERIKKPTSAVVSSNASRRKLINYTKKHLSSHSSTNSNSKPSTASPSAHTSSSDGNNEIFTCQIMNLITNEPCGAQFSRSYDLTRHQNTIHAKRKIVFRCSECIKILGSEGYQKTFSRLDALTRHIKSKHEDLSLEQRQEVTKFAKANIGYVMG
What is the function of this protein?
Acts as a transcriptional activator of a number of genes encoding proteasomal subunits.  Binds to a PACE (proteasome-associated control element) DNA sequence 5'-GGTGGCAAA-3'.  Its expression is in turn regulated by the 26S proteasome, thereby providing a negative feedback control mechanism.  Required for normal growth at low temperatures.
What are the official names of this protein?
Protein RPN4, Nuclear protein SON1, Ubiquitin fusion degradation protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRMA_GEOKA
Sequence: MKWSEISIHTTHEAVEAISNILHEAGAGGVVIEDPYDLVKERDDWYGEIVELNPDDYPEEGVIIKAYLPVNSFLGETVEQIKQAINNLWLYDIDLGKNKITLSEVNEEEWATAWKKHYHPVKVSEKFTIVPTWETYEPASRDELIIEMDPGMAFGTGTHPTTVMCLQALEKYVRPGDHVIDVGTGSGILSIAAAMLGAQSVRALDLDPVAVDSARLNVKLNKVQHIVTVSQNNLLDHIEEPADVIVANILAEIILRFTGDAYRLLKPGGRFITSGIIQAKKQDVKDGLLAAGFAIEEINVMEDWVAVVALKP
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTGCB_ECO57
Sequence: MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVVSHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLHLPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLAAIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPFQMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPENRAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDGTSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATEDAKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVVAGSGVQAIFGTKSDNLKTEMDEYIRNH
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of PtsG and Crr is involved in glucose transport.  Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration.
What are the official names of this protein?
PTS system glucose-specific EIICB component, EIICB-Glc, EII-Glc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEP5_ARTBE
Sequence: MHGLLLAAAGLLSLPLHVIAHPQPSTNLAGRGVDLDAYRMADRSSYMNSDDMKLKQPGIASLSGGNYVDTATEVVKRMMPGMTFRMVDDHYVGESGISHVYFRQTMHGMDIDNSDFNVNIGKDGKVLSFGHSFYTGPAPDKAPVEKRDFSDPMKAFHGACKALSLPINADKATVQTMNEHEVMFMGTSGAMSDPQGKLCYMAKEDGTLALTWRVETDMGDNWLLSYVDAKETEKVHNVVDYVSHATYQVYRRALSPDPTEGKRESIENPWNLKTSPFTWISDGKTNYTTTRGNNAIAQANFDGGEDYLNNHRPNNKNLKFEYPYAPNMSPKSYIDASVTQLFYSANMVHDLYYMLGFTEKAGNFQVNNHGQGGKGNDFVILNAQDGSGTNNANFATPPDGKPGRMRVYIWTKAKPARDSSFEAGTVIHEYTHGLSNRLTGGPANAGCLNGMESGGMGEGWGDFFATAIRLKPNDNRNANYVHGEWVNNSPKGNRMYPYSTSLQTNPLVYTSCNKYNEVHAIGTVWGSMLYEVLWNLIDKHGKNDGPTPVFENGVPKDGKYLAMKLVMDGMAIQPCKPTFVQARDAIIDADMNLTKGSNRCEIWKAFAKRGLGVGAKYDPKNRTGNKGLPKDCQ
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 5, Fungalysin MEP5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TIM10_BOVIN
Sequence: MDPLRAQQLAAELEVEMMADMYNRMTSACHRKCVPPHYKEAELSKGESVCLDRCVSKYLDIHERMGKKLTELSMQDEELMKRAQQSSGPV
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim10.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: CNTN4_HUMAN
Sequence: MRLPWELLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL
What is the function of this protein?
Contactins mediate cell surface interactions during nervous system development.  Has some neurite outgrowth-promoting activity.  May be involved in synaptogenesis.
What are the official names of this protein?
Contactin-4, Brain-derived immunoglobulin superfamily protein 2, BIG-2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. Contactin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted.