PharMolix/UniProtQA huggingface dataset:
Protein: PUR9_SORC5
Sequence: MIRRALISVSDKTGLLPLARRLAEKGVEILSTGGTQRALADAGVPVIGVEAYTGSPEVMDGRVKTLHPRVHGGILMRGAIDDEDLARLGGAPIDLVVCNLYPFEATVRKPGVTHPEIIENIDIGGPSMVRSAAKNHARVAVVVDPADYDAVLAEIDRQGEVSSATRRRLATKAFAHTAAYDGMVSGYLSSLPEEGEPSAAEREAYPRFLTLALERAYPLRYGENPHQSGAFYRERGAAAGSLALAESLGAGGKELSFNNLVDVDAAFEAVREFTQPAAVVVKHTNPCGVATGDSLAAAYRTARDADAVSAFGGIVALNREVDRAAAEVLVETFLECVVAPAYTPDALEVLRTKKNLRLLATGALLPADHRELTFKRVGGGLVVQERDASAAGEVRGGRVVAKRAPTEEEIEALDLGWRVCKHVKSNAIVLAIPGRTVGIGAGQMSRVESVRIACSKAGERARGSVLASDAFFPFPDNVVLAAEHGITAVAQPGGSVKDAEVIAAADAAGIAMVFTGARHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: UBIG_PSE14
Sequence: MSNVDRAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERVGLAGKKVLDVGCGGGILSEAMALRGATVTGIDMGEAPLAVAQLHQLESGVSVEYRQITAEDMAEEMPEQYDVVTCLEMLEHVPDPSSVIRACYRMVKPGGQVFFSTINRNPKAYLFAVVGAEYILNLLPRGTHDFKKFIRPSELGAWSRDAGLQVKDVIGLTYNPLTKHYKLTSDVGVNYMIQTLREA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: PAND_GRAFK
Sequence: MQIHVVKSKIHRVKVTGADLDYIGSITIDEDLMEAASIIEGEKVQIVNNNNGERLETYVIPGLRNTGEITLNGAAARKVAKGDILIIIAYGIMELEEARNFKPSLVFPDEETNLLK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_HELAN
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MANF_RAT
Sequence: MWATRGLAVALALSVLPDSRALRPGDCEVCISYLGRFYQDLKDRDVTFSPATIEEELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGEMCKGCAEKSDYIRKINELMPKYAPKAASARTDL
What is the function of this protein?
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain (By similarity).  Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra (PubMed:16462600).  Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (PubMed:16462600).  Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death (By similarity).  Retained in the ER/sarcoplasmic reticulum (SR) through association with the endoplasmic reticulum chaperone protein HSPA5 under normal conditions (By similarity).  Up-regulated and secreted by the ER/SR in response to ER stress and hypoxia (By similarity).  Following secretion by the ER/SR, directly binds to 3-O-sulfogalactosylceramide, a lipid sulfatide in the outer cell membrane of target cells (By similarity).  Sulfatide binding promotes its cellular uptake by endocytosis, and is required for its role in alleviating ER stress and cell toxicity under hypoxic and ER stress conditions (By similarity).
What are the official names of this protein?
Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich protein, Protein ARMET.
What is the protein family that this protein belongs to?
Belongs to the ARMET family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Note=Retained in the endoplasmic reticulum (ER), and sarcoplasmic reticulum (SR) under normal conditions. Up-regulated and secreted by the ER/SR in response to ER stress and hypoxia.
Protein: FTSQ_THIA3
Sequence: MSSYAPREIPLDIRLMQGTSRALFWLVALGCLFVAGHWLMQRNWWDIRAVRLQGDLQRISPVTVRAEALPQLRGNFLTINLAQAQRVFESLPWVRTAVVQRLWPMQLAVTLQAQQPVAIWREPGSAAQLVNTQGQAFTANLGEVQGLGLPQLSGPAGTSAQVLQMSQKLQPLMQEFHQTVATLAQGSGGNWSVQTRSGLSIDLGSAPDSAATQTRLKQFMTLMPQLEARYGRSIDSVDLRYPNGFAVHLQGVDLPGMNKTSNKTPQPAGRKD
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: BIG1_CANAL
Sequence: MRLFVLLAYIIPFILCQLTPVLVASHKLVRGLKEEINPSNTLPHNVTSVTNMLKKLITECSSDAYLLINQPGLTYADLTTEKKDNWPFLRNYLYMSSTIVGLPRVENPIDLDFLEQYIISNCDAETINVWHDSEDEVVDYYDIRKRVIRIDLSPLSISNHDDRVKEIFEHDQLIRKILRKLPSAHYTIILTSLEPGIIHPVPRFLMEETPASFEIFDDIINDPFHNREIEKNDRFHKVEPNWNPIRDSNDRYYRNKKKDEIHLFDYELWEKNEKLITTIFVMVLSLFMMKIISFFNYLKQKIIQKKQQKSKRGIIADDKKLD
What is the function of this protein?
Required for normal beta-1,6-glucan synthesis, for hyphal morphogenesis, adhesion and virulence.
What are the official names of this protein?
Protein BIG1.
What is the protein family that this protein belongs to?
Belongs to the BIG1 family.
Protein: NAT14_MOUSE
Sequence: MAPNHLSVREMREDEKPLVLEMLKAGVKDTENRVALHALTRPPALLLLAAASSGLRFILASFALALLLPVFLAVAAVKLGLRARWGSLPPPGGLGGPWVAVRGSGDVCGVLALAPGANVGDGARVTRLSVSRWHRRRGVGRRLLAFAEARARAWAGSMGEPRARLVVPVAVAAWGVAGLLEACGYQAEGGWGCMGYMLVREFSKDL
What is the function of this protein?
May act as a transcription factor regulating the expression of coproporphyrinogen oxidase by binding to a promoter regulatory element.
What are the official names of this protein?
Probable N-acetyltransferase 14.
What is the protein family that this protein belongs to?
Belongs to the camello family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CP51_CANTR
Sequence: MAIVDTAIDGINYFLSLSLTQQITILVVFPFIYNIAWQLLYSLRKDRVPMVFYWIPWFGSAASYGMQPYEFFEKCRLKYGDVFSFMLLGKVMTVYLGPKGHEFIYNAKLSDVSAEEAYTHLTTPVFGKGVIYDCPNSRLMEQKKFAKFALTTDSFKTYVPKIREEVLNYFVNDVSFKTKERDHGVASVMKTQPEITIFTASRCLFGDEMRKSFDRSFAQLYADLDKGFTPINFVFPNLPLPHYWRRDAAQRKISAHYMKEIKRRRESGDIDPKRDLIDSLLVNSTYKDGVKMTDQEIANLLIGVLMGGQHTSASTSAWFLLHLAEQPQLQDDLYEELTNLLKEKGGDLNDLTYEDLQKLPLVNNTIKETLRMHMPLHSIFRKVMNPLRVPNTKYVIPKGHYVLVSAGYAHTSDRWFEHPEHFNPRRWESDDTKASAVSFNSEDTVDYGFGKISKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILTTYIYNFKWRLNGDKVPDVDYQSMVTLPLEPAEIVWEKRDTCMV
What is the function of this protein?
Sterol 14alpha-demethylase that plays a critical role in the third module of ergosterol biosynthesis pathway, being ergosterol the major sterol component in fungal membranes that participates in a variety of functions (By similarity).  The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane (By similarity).  In filamentous fungi, during the initial step of this module, lanosterol (lanosta-8,24-dien-3beta-ol) can be metabolized to eburicol (By similarity).  Sterol 14alpha-demethylase catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of both these sterols in the form of formate, and converts eburicol and lanosterol to 14-demethyleburicol (4,4,24-trimethylergosta-8,14,24(28)-trienol) and 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol, respectively, which are further metabolized by other enzymes in the pathway to ergosterol (By similarity).  Can also use susbtrates not intrinsic to fungi, such as 24,25-dihydrolanosterol (DHL), producing 4,4-dimethyl-8,14-cholestadien-3-beta-ol, but at lower rates than the endogenous substrates (By similarity).
What are the official names of this protein?
Lanosterol 14-alpha demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-14DM, Cytochrome P450-LIA1, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: SURE_CITK8
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHQHYETAAAVTCSILRALRREPLRTGRILNINVPDLPLDQIKGIRVTRCGSRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPDTDFAAVDEGYVSVTPLHVDLTAYSAHDVVSDWLDSVGVDAQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGS_PYRTR
Sequence: MFIWTKAPARGLGKASKILPKRDDTQKVFETTHHKQFHTATTSVRRSSSSAKERQRAERQQLTRLLKESPGKRDARNFLKQFDVPKKSKASITAKAKELVSENIHNDLASLRTGVNLGDLYKPTVFTREPLPEESYDAEKDEPVHLALVKLRQPQKLTDRTLGDIALTLSQMARLGLSTAVVLDCDEDTSTHSIEVKPEYGNMVREQALRLVAALEDYNEPGSLLVEDVLGYSPLDNDMPSTNQVRGGVEVQHTYLLFPPIDDGVIPVIAPFAYDENLKKVRVQADDVLLALVREFAGLGHSNGMESPRGSLHKTKRVVERPLLDRIIILDPLGGIPSENRADGAHVFVNLEAEYRDIKKELQQLSSKTSNGAGSPTSLSTGNPLSKFVEQEVVSLPGVQSENLASSAPVRHLKNLDVLERGLKLLPPSSSGLILTPMEAATKAIPDDARTTPSKNPLLHNLLTDKPMTSSSLPTSPTSRFLGSAAPNPATFLKKGIPLTMIPDPRVHGPWQPPSASNPSIELADDPRINFPKLVDLIDDSFQRKLHPKNYLDRIHGRVAGIIIAGDYEGGAICTWETPKSLQGATPPSVLTPDSPYWIPYLDKFAVLTSSQGSGGVSDIVWAALTRTCFPDGVVWRSRTSNPVNKWYQERSMGMWKLPGDQWTMFWTTEGIVGGWEQGKWGDVDDAKKRDMKRWDACIDVCSGIEPSWADGIQRDD
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BIOB_YERPE
Sequence: MATYHHWTVGQALALFDKPLLELLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLESERLMQVEQVLESAKKAKAAGSTRFCMGAAWKNPHERDMPYLAKMVEGVKALGMETCMTLGSLSKQQAHRLADAGLDYYNHNLDTSPEFYGSIITTRSYQERLDTLNEVRDAGIKVCSGGIVGLGETVRDRAGLLVQLANLPKPPESVPINMLVKVKGTPLENNAEVDAFEFIRTIAVARIMMPSSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPDEDKDLQLFRKLGLNPQQTATSHGDREQQQALTEQLLHGDTAQFYNAAV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CH60_SODGM
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPVITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVIAAVEELKKLSVPCSDSKAIAQVGTISANADETVGTLIAEAMAKVGKEGVITVEEGSGLQDELDVVEGMQFDRGYLSPYFVNKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKIAAVKAPGFGDRRKAMLQDIAILTAGTVISEEIGLELEKATLEDMGQAKRVVITKDTTTIIDGEGDKALIDSRVTQINQQRDEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVANRIAELRGDNEDQNVGIKVARRAMEAPLRQIVANAGEEPSVIANKVKAGEGNTGYNAATEEYGNMIDMGILDPTKVTRSALQYAASIAGLMITTECMVTDLPKEDKPDLGGAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_PSEPW
Sequence: MTQDQLKQAVAQAAVDFILPKLDEKSVVGVGTGSTANFFIDALAQHKTAFDGAVASSEATAQRLKGHGIPVYELNSVSELEFYVDGADESDAHLNLIKGGGAALTREKIVAAVAKTFICIADASKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYREGVVTDNGNVILDVYNLQITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTPEGVKSLKAE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PUR5_PROMH
Sequence: MTNKSSLSYKDAGVDIDAGNALVDRIKSVVKETRRPEVMGGLGGFGALCAIPTKYREPILVSGTDGVGTKLRLAMDLNRHDDIGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVDTAARVVTGIAEGCKQSGCALVGGETAEMPGMYHGNDYDIAGFCVGVVEKSQIIDGSKVKAGDALIALASSGPHSNGYSLIRKILEVSGACAETTPLGDTSLADKLLAPTRIYVKSLLSLIENVDIHAVAHITGGGFWENIPRVLPENTQARINSQSWQWPEVFNWLQQAGNVSTHEMYRTFNCGVGLLIAVSQADVEKTLSHLNACGEKAWLIGDIAPQAAGDAQVIIN
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKFE_EMENI
Sequence: MYSKSWILNALPAPLVPYCELTRVGYLPIGVLVSYLPVLVAILHVAAVARLPYDNILDSCLQWLPLCYVYSAYGCVVDDIADQDLDRKVERCQHRPLVRGAVSTTSACLFAASLASLAVFLTKTFFPDQPAVHIPVALAGSIIYPFLKRFTNFALLYLAFLYVATGLNASRTIGYDILSAPDHLLTSNLLLAAAVFIANVSVETIYMHADLEDDIKSGIGSLAVKIQGYSKPVLFLAAVAYGSLVLASGLAAEFGKWYFTGAITSALTLFTLVARVDLKNGKMCEQFFFMGNAVLMSLLAAGLYGECIA
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of aspernidine A, a prenylated isoindolinone (PubMed:23706169).  The starting point of the biosynthesis of aspernidin A is the production of orsellinaldehyde by the non-reducing polyketide synthase pkfA (PubMed:22510154).  Hydroxylation, methylation of one of the phenol groups, and prenylation, presumably catalyzed by the prenyltransferase pkfE, would be needed to yield aspernidine D (Probable).  Subsequently, the cytochrome P450 monooxygenase pkfB is responsible for hydroxylation of aspernidine D to yield aspernidine E (PubMed:23706169).  The dehydrogenase pkfF may be responsible for further oxidation of aspernidine E to form a dialdehyde intermediate which is further transformed in a series of steps, some of which are enzyme-mediated, to generate aspernidine A (Probable).  The possibility that additional enzymes outside of the cluster are involved in aspernidine A biosynthesis cannot be excluded (Probable).
What are the official names of this protein?
Prenyltransferase pkfE, Aspernidine A biosynthesis cluster protein pkfE.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HOA1_RHOE4
Sequence: MSDMIHFDSSWDIRVTDTSLRDGSHHKRHQFTVEEVRAIVGALDGAGVPVIEVTHGDGLGGSSFNYGFSKTPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHCTEADVSIQHFGLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSDRVEALVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAFVGVCDKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAERQAERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQREAAAS
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: RPOZ_PSESM
Sequence: MARVTVEDCLEHVDNRFELVMLSTKRARQLATGGKEPKLAWENDKPTVMALREIAAGLMDYAVIAEAEIVEDEPLFAAFEDESNEAV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PYRC_THEPX
Sequence: MRMIIKNGTVIDGFGSEATADILIDYGIIKAIDKNIQVSDGIVIDATGKYVLPGFVDMHTHLRQPGFEEKETIKTGTEAAATGGYTTVACMPNTNPPIDNEIVVEYVKSIAQREGVVKVLPIGAMTKGMKGEEITEMAKLKKAGVVALSDDGFPIMSAGLMKRIMTYGKMYDLLMITHCEDKALSGEGVMNSGVISTMIGLKGIPREAEEVMLARNIILAKSTGVRLHIAHISTKGSVELIREAKEKGVKITAEVTPHNLTLTDEAVYNYDTNTKAYPPLRTREDIEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAAFGISGLETAFSVINTFLVQTGKITIKELVNYMSINPAKILGISSGIKVGSIADIVIVDPYEEYVVDKDKFKSKGKNTPFHGMRLKGVVDCTIVEGEIKYKKDRKTEKVEV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: Y268_ARCFU
Sequence: MGSLKDAEKEGLNVCSDLSGHVSIARYIEEEYEVLIF
What are the official names of this protein?
Uncharacterized protein AF_0268.
Protein: Y324_MYCLB
Sequence: MPGNSRRRGAVRKSGTNKGTTVGSGGQRRRALEGRGPTPPAYLRPNHPAAKRNQSSPHRPVKRTDETETVLGRNPVLECLRAGVPATALYVALGTEVDKRLTESVMRAADVGVAILEVPRTYLDRITNNHLHQGIALQVPPYHYVHSDDLLAAATDSPPALLVALDNISDPRNLGAIVRSVAAFSGHGILIPQRRSASVTAVAWRTSAGAAARIPVARATNLTRALKVWADQGLRVIGLDHDGDTALDDLDGTDPLAVVVGSEGKGLSRLVRHSCDEVVSIPMAGQVESLNASVAVGVVLAEIARQRRL
What are the official names of this protein?
Uncharacterized tRNA/rRNA methyltransferase MLBr00324.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: VRAS_STAAM
Sequence: MNHYNRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
What is the function of this protein?
Member of the two-component regulatory system PprA/PprB involved in biofilm formation by controlling the expression of many related genes including type IVb pili major subunit flp pilin, adhesin bapA or cupE fimbriae.  Modulates also quorum-sensing signal production acting on both negative and positive modulators.  Functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to PprB.
What are the official names of this protein?
Sensor protein VraS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YUC2_ARATH
Sequence: MEFVTETLGKRIHDPYVEETRCLMIPGPIIVGSGPSGLATAACLKSRDIPSLILERSTCIASLWQHKTYDRLRLHLPKDFCELPLMPFPSSYPTYPTKQQFVQYLESYAEHFDLKPVFNQTVEEAKFDRRCGLWRVRTTGGKKDETMEYVSRWLVVATGENAEEVMPEIDGIPDFGGPILHTSSYKSGEIFSEKKILVVGCGNSGMEVCLDLCNFNALPSLVVRDSVHVLPQEMLGISTFGISTSLLKWFPVHVVDRFLLRMSRLVLGDTDRLGLVRPKLGPLERKIKCGKTPVLDVGTLAKIRSGHIKVYPELKRVMHYSAEFVDGRVDNFDAIILATGYKSNVPMWLKGVNMFSEKDGFPHKPFPNGWKGESGLYAVGFTKLGLLGAAIDAKKIAEDIEVQRHFLPLARPQHC
What is the function of this protein?
Involved in auxin biosynthesis.  Converts the indole-3-pyruvic acid (IPA) produced by the TAA family to indole-3-acetic acid (IAA).  Unable to use tryptamine (TAM) as substrate.  Required for the formation of floral organs and vascular tissues.  Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots.
What are the official names of this protein?
Indole-3-pyruvate monooxygenase YUCCA2, Flavin-containing monooxygenase YUCCA2.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: CIAO1_DROER
Sequence: MGRLILEHTLQGHKGRIWGVAWHPKGNVFASCGEDKAIRIWSLTGSTWSTKTILSDGHKRTIREIRWSPCGQYLASASFDATTAIWSKSSGEFECNATLEGHENEVKSVSWSRSGGLLATCSRDKSVWIWEVAGDDEFECAAVLNSHTQDVKRVVWHPTKEVLASASYDNTIKMYAEDPVDNDWDCTATLTSHTSTIWGIDFDADGERLVSCSDDTTIKIWKAYHPGNSAGVATPDQQTVWKCVCTLSGQHSRAIYDVSWCKLTGLIATACGDDGIRIFKETSDSKPDEPTFEQLTAEEGAHDQDVNSVQWNPVVAGQLISCSDDGTIKIWKVTE
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein Ciao1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
Protein: H18B1_CYRHA
Sequence: MKLSIIIIATSLVIAVVAFPSKDSKAIENDKTEQRMEIVVQETARACSKQIGDKRKRNCECCGKTVVCGTIYVGGKEVNQCMDKTSDNAILNGLGKGMNFIENTFSFCV
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XVIII-2, HNTX-XVIII-2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. F7 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM3_AERPE
Sequence: MRVRVAARGSRLSLLQVEQALEELSRYAGVSMHWEVVRVKSAGDVWSDRPLESIGVVGVFTREVDRAVASGAADIAVHSLKDMPTSGYGGPLKIVYIASRPSARDALISRQGPGRVEDLEPGSTLGTSSARRRALSLHYNPRIRVENLRGNLDTRLRKLREGLYDAIIASEAGLIRLGVDVEYTPLDPSYFPPAPGQGFVAVVARVGSNVEKMLRDLDKPPWWHVAWAERGVLEGARAGCRTPVAAYAEPLGRSMVRVTAAALSPDGSRAYWARAEGRIEEARRIGVSLGEELSRVVEGWHKTGGGS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CYA4_TRYBB
Sequence: MNMLHLSDRNASLAPSGGEHSLPTGGAVCRDAMDILPVILRAPVALLLLLVVLPQLSVGAEANVTVKVLSATWNWYMPRKYVTAINAGFNASLKSRNWTVAGSVNVQVVYPSNLDLMPEDFIKKQLELETDQNKIVIVYGPLGDKSVMHSIPHLMNHRVVAFGLITGSTFIRQWNPYLYFLRADPAAETLVLIRYSLCQLRVLRLGFMYLQGVHYGDEEYALTVNVMSRMGYELHGVFTVMSPDGKPAPDAEFKEVFERFATALPQAIIVFGAPVDDTAKFLMMMAVDERIARSYILSPSSVQLSLIEMWQLALEAAGASFAPGQLLFTGTNPLAKDSQYTAIKRFQEVMSEYLKAHVGETNITEADYFLTHDLEGELMVYGWISGEVLSQALSNLEWLKDRATFVRSLYDQRRYVINDIVIGDYGGTCEGDAAKHGATCECNQGSKAVYVKEMLENGQKTSVRSGFTVLKASLCYTDSSELHGPLDGLVVFMKDDDIASKAAALWQKGTSHLVGKGDLGYSDRFFLHAFNTTIAEAANDLRRDQGERIVTAVFGPVTEAMLDTPNITFIDPLELKPRLNKFRRNVIHLSPTLEQQLYVLSSYLAGAGVGNVDAVICSNEADGIADFLRSSLTEFAVSLRSAVIREDGEDVGKYLPMSGTVFVIGLSVPDVKEIARKLEERNDLRVIVLFGEFSFLYDLFATALNNTAGAARLVFATSLPHWGDTETSSKTAQLFHDVEKDSRLWTPLSVLAFATGRLMRVILLHVEEMSPETLVNFFYTDSSIVSDDMRYGVFDDTKCVDTANKLSKNGCASNYGATQISVWSMARALNASIPPLTNPMTPSMTFRNSNAGRISGASLVGIIIGGALALFLVVALGVVPYFFLRNTVITICTKDDRPVTLIFTDIESSTALWAAHPEVMPDAVATHHRLIRTLISKYECYEVKTVGDSFMIASKSPFAAVQLAQELQLCFLHHDWGTNAIDESYQQFEQQRAEDDSDYTPPTARLDPKVYSRLWNGLRVRVGIHTGLCDIRRDEVTKGYDYYGRTSNMAARTESVANGGQVLMTHAAYMSLSAEERQQIDVTALGDVPLRGVPKPVEMYRLNAVPGRTFSVLRLELELLNDDEDQTTTSCSDHSSSRTDLSVAAQTIAASLQSLLGTFTPAQRQKALIPFCERWRVPLPQKVGNVWDDDGCQEVVRRVAAKVGRVMDFGTRKPSSSVTSWKGVEVSSQVEERLL
What is the function of this protein?
Could act as a receptor for an unknown ligand.
What are the official names of this protein?
Receptor-type adenylate cyclase ESAG 4, ATP pyrophosphate-lyase, Adenylyl cyclase, Antigen 4, Expression site-associated protein 4.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.