PharMolix/UniProtQA huggingface dataset:
Protein: SR541_HORVU
Sequence: MVLAQLGGSISRALAQMSNATVIDEKVLGECLNEISRALLQSDVQFKMVRDMQTNIRKIVNLETLAAGTNKRRIIQQAVFTELCNMLDPGKPAFTTKKGKPSVVMFVGLQGSGKTTTCTKYAYYHQRKGFKPSLVCADTFRAGAFDQLKQNATKAKIPFYGSYMESDPVKIAVEGLERFRKENSDLIIIDTSGRHKQEAALFEEMRQVAEATKPDLVIFVMDGSIGQAAFDQAQAFKQSASVGAVIITKLDGHAKGGGALSAVAATKSPVIFIGTGEHIDEFEIFDVKPFVSRLLGMGDLSGLMDKIQDVMPADQQPELLAKLAEGTFTLRLLYEQFQNLLKMGPIGQVFSMLPGFSSELMPKGHEKEGQAKIKRYMTIMDSMTAAELDSTNPKLMTESRIIRIARGSGRQIRDVTDMLEEYKRLAKMWSKMKGLKMPKNGKMSDLSQNLNIQQMTKALPPQVLKQMGGMGGLQALMKQMGGKDMSKMLGGMGLGGD
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).  As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane.  Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.  Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA.  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA.  SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER (By similarity).  Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP54 1, Signal recognition particle 54 kDa protein 1, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_METTH
Sequence: MLNQLQRDILRLKKEKNAIILAHNYQSREIQEIADFKGDSLELCIEASRIEGKDIVVFCGVDFMAETAYILNPDKKILIPDRGAECPMAHMLSAEDVRMARKRYPDAAVVLYVNTLAEAKAEADILCTSANAVRVVESLDEDLVLFGPDRNLAWYVQEHTDKTIIPIPEEGHCYVHKMFTAGDVMAAKEKYPEAELLIHPECDPEVQELADHILSTGGMLRRVLESDAESFIIGTEVDMTTRISLESDKKTIPLLEEAICENMKLHTLEKVKNSLINEEFVVTVPDEIARRARRAVERMIRVSE
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_ALKOO
Sequence: MSIIRDVYAREVLDSRGNPTIEVEVYLESGAIGRTIVPSGASTGAFEAVELRDGDKGRYLGKGVQKAVENVNQIIAPEIIGLDAVEQVVIDEMMIELDGTPNKSKLGANAILGVSMAVAKAAAEALGLPLYQYLGGVNAKQLPVPMMNILNGGAHADNNVDIQEFMIMPVGAANFSSGLRMCVEIYHNLKSVLKEKGLGTGVGDEGGFAPNLGSNEEALQVIVEAIEKTGYTPGVDVKLALDVAATELYDETEKLYRLSGEGVVKTAAEMVDFYEELINKYPIISIEDGLSEEDWDGWKLMTERLGKKIQIVGDDLFVTNTERLEKGIKQGTANSILIKLNQIGTITETLDAIEMAKRAGYTAVISHRSGESEDSTIADVAVAVNAGQIKTGAPARTDRVAKYNQLLRIEDMLGFTAKYLGEDVFYNL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RUVA_LATSS
Sequence: MYEYLKGLVTAVNPYYVVLEVQGIGYQLQVANPYRYTESMSEVVQIFVHQAVRDTDITLFGFYDLDEKQLFQKLISVSGIGPKSALAILANSDHSGLIQAIMNDDIGYLTKFPGVGKKTAQQIALDLKGKLGDLEQSATLVGQTAIDLGSQGDSPELSDALAALSALGYSAREVKAITPKLTDFAAQTTDQYLREGLRLLMKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: EDS1L_ARATH
Sequence: MAFEALTGINGDLITRSWSASKQAYLTERYHKEEAGAVVIFAFQPSFSEKDFFDPDNKSSFGEIKLNRVQFPCMRKIGKGDVATVNEAFLKNLEAVIDPRTSFQASVEMAVRSRKQIVFTGHSSGGATAILATVWYLEKYFIRNPNVYLEPRCVTFGAPLVGDSIFSHALGREKWSRFFVNFVTRFDIVPRITLARKASVEETLPHVLAQLDPRNSSVQESEQRITEFYTSVMRDTSTVANQAVCELTGSAEAILETLSSFLELSPYRPAGTFVFSTEKRLVAVNNSDAILQMLFYTCQASDEQEWSLIPFRSIRDHHSYEELVQSMGMKLFNHLDGENSIESSLNDLGVSTRGRQYVQAALEEEKKRVENQKKIIQVIQQERFLKKLAWIEDEYKPKCQAHKNGYYDSFKVSNEENDFKANVKRAELAGVFDEVLGLLKKCQLPDEFEGDIDWIKLATRYRRLVEPLDIANYHRHLKNEDTGPYMKRGRPTRYIYAQRGYEHHILKPNGMIAEDVFWNKVNGLNLGLQLEEIQETLKNSGSECGSCFWAEVEELKGKPYEEVEVRVKTLEGMLREWITAGEVDEKEIFLEGSTFRKWWITLPKNHKSHSPLRDYMMDEITDT
What is the function of this protein?
Positive regulator of basal resistance and of effector-triggered immunity specifically mediated by TIR-NB-LRR resistance proteins.  Disruption by bacterial effector of EDS1-TIR-NB-LRR resistance protein interactions constitutes the first step in resistance activation (PubMed:22158819).  Triggers early plant defenses and hypersensitive response independently of PAD4, and then recruits PAD4 to potentiate plant defenses through the accumulation of salicylic acid (PubMed:11574472).  Nuclear localization is essential for basal and TIR-NB-LRR-conditioned immunity and for reprogramming defense gene expression, while cytoplasmic EDS1 is required to induce a complete immune response (PubMed:20617163).  Heterodimerization with PAD4 or SGA101 is necessary for TNL-mediated effector-triggered immunity (PubMed:24331460).  Contributes to nonhost resistance against E. amylovora (PubMed:22316300).  Has no direct lipase activity (PubMed:16040633).
What are the official names of this protein?
Protein EDS1L, Enhanced disease susceptibility 1-like.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Microsome. Note=Found in both the nucleus and diffuse in the cytosol when associated with PAD4, in the nucleus and in punctate spots in the cytoplasm when interacting with SRFR1, SNC1 or RPS4, only in the nucleus when associated with SAG101 and in the cytosol when it dimerizes. Interacts with AvrRps4 and HopA1 effectors in microsomes.
Protein: NIFH1_TRIV2
Sequence: MTDENIRQIAFYGKGGIGKSTTSQNTLAAMAEMGQRIMIVGCDPKADSTRLMLHAKAQTTVLHLAAERGAVEDLELHEVMLTGFRGVRCVESGGPEPGVGCAGRGIITAINFLEENGAYQDLDFVSYDVLGDVVCGGFAMPIREGKAQEIYIVTSGEMMAMYAANNIARGILKYAHSGGVRLGGLICNSRKTDREAELIENLAERLNTQMIHFVPRDNIVQHAELRRMTVNEYAPDSNQGQEYRALAKKIINNDKLTIPTPIEMDELEALLIEYGILDDDSKHAEIIGKPAEATK
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 1, Nitrogenase Fe protein 1, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: UBID_ECOK1
Sequence: MKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PFDA_HALMA
Sequence: MMGGGGGGGGGGQMQQVAQEIEQMEQEVEAIDEEIERLREKQTDIDEAIEAIETLDSGSTVQVPLGGDAYIRATIEDIDEVVVSLGGGYSAEREQDGAVSTLETKKETLDDHISDLQEEKAEVETEMEELEQQAQQMQQQQMQQMMQQQEQEDE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_COXBN
Sequence: MAQAAKKQNLGTGRRKTSSARVFLRSGTGQIIINGLPLDEYFGRETARMVVRQPLVKLDVQSRFDVYATVQGGGDSGQAGAIRHGITRALIQYDEEGGEGGTWRSTLRKAGFVTRDPRMVERKKVGLHGARRGTQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: URED_ACIBC
Sequence: MNRIQQTFQTSSAPFWYAQLELGFCYENSRTIMSHRKHYGPVRVQKMLWPEKTGVCHAIIVHPPAGIAGGDHLTFQIETERQAHAVITTPGAGKWYRTNGKHAFQHIYLNVKDDSILEWMPQETMLFDGALAHSETDIHLEQTASFIGWDMLVLGRQARAENFVQGSYHNQFKLWRKNKLLVADTLYFEGGDRWLSSCLGMNNQAVMASFWAVPPEKFRSSFYLEQHIELIRELIMRMDVPVTLTLLEDVLCARFLGNDVRRCHDAFAAIRAKLRRYWFDLDEEFPRIWKT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_PAEAT
Sequence: METVNTAIQPEKTRRRVLLKLSGEVIGGGKLGVDPETVRAIAKQIAAAVTEVEVAIVVGGGNFFRGAELSQSGMDRSRADYMGMLGTVMNCLALQDFLEQAGVETRVQSAITMGQVAEAYIPRRAIRHMEKGRVVIFGAGAGLPYFSTDTVAAQRALEVHADVVLMAKSGVDGVYTADPKKDPTAEKLDVLSYDDALRRDIRVMDQTAMTMCKDNSLSMVVFGMEGEGNVTRAILGETLGTLVTP
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCC1_STAAN
Sequence: MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
What are the official names of this protein?
Carbamate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAST_DIDVI
Sequence: QLGPQDLPYLTADLSKKQGPWLEEEEAYGWMDF
What is the function of this protein?
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes.  It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
What are the official names of this protein?
Gastrin.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: H33_HUMAN
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DGTL1_MYCSK
Sequence: MNPRLQDSYDEFDRQRRVDEPAKSAVLPGTGTEHRTDFARDRARVLHCAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAVGLGCDPDLVDLAGLAHDIGHPPYGHNGERALNEIAKAFGGFEGNAQNFRILTRLEPKVLDATGRSAGLNLTRAALDAVTKYPWQRGDRTKFGFYGDDMAAAWWVRDGAPAERPCLEAQVMDWADDVAYSVHDVEDGVVSGRIDLRVLADDDAAASLARLGAEAFPTLAPDDLLAAAERLSQMPVVSQVGKYDGTLGASVALKRMTSELVGRFANAAITETRSVAGGGALHRFVTELAVPTLVRAEVAVLKMLALQFIMSDHGHLGIQADQRTRIHEVALILWGQAPSSLDPLFAPEFVAAEDDGARLRVVIDQIASYTEGRLERVHEARSPRPLD
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: SUMO2_CRIGR
Sequence: MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY
What is the function of this protein?
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer.  Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.  This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.  Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.  Plays a role in the regulation of sumoylation status of SETX (By similarity).
What are the official names of this protein?
Small ubiquitin-related modifier 2, SUMO-2, MIF2 suppressor.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: RL5_MYCMS
Sequence: MKSRLEIKYKDQIVPELFKELNYKSIMQVPKIQKIVINMGIGDATTDPKKLDAAISELEKLSGQKPIVTKAKKSLAVFKLREGMAIGAKVTLRGKKMYDFLDKLINVALPRVRDFRGVSKTSFDGFGNFTTGIKEQIIFPEVDYDKVIRLRGMDITIVTSAKTNKEAFALLQKVGMPFEK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RPOZ_LISW6
Sequence: MLYPSIDNLLLKIDSKYSLVTVAAKRARYMQLENDKGVLPSYQSDKFVGKALEEIHAGKLVLKNDEK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: IF4E2_TOBAC
Sequence: MVDEVEKPVSLEESKTNTREVEEEGEIVGESDDTMSSLGNPSMAMKHALEHSWTFWFDNPSGKSKQAAWGSSIRPIYTFSTVEDFWSVYNNIHHPSKLAVGADFHCFKNKIEPKWEDPVCANGGKWTMSFSRGKSDTCWLYTLLAMIGEQFDCGDEICGAVINVRVRQEKIALWTRNAANETAQVSIGKQWKEFLDYNDSVGFIFHDDAKKLDRAAKNRYSV
What is the function of this protein?
(Microbial infection) Susceptibility host factor required for viral infection (e. g.  potato virus Y (PVY) and pepper mottle virus (PepMoV)) by recruiting viral RNAs to the host ribosomal complex via an interaction with viral genome-linked protein (VPg).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-2, NteIF4E2, eIF4E-2, Eukaryotic translation initiation factor 4E2-S, eIF4E2-S, eIF-4F 25 kDa subunit, eIF-4F p26 subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NUOH_FRATW
Sequence: MLGYILWTSLYVLLIVIPLILVVAYYTYAERKVIGYMQDRIGPNRVGSFGLLQPIFDALKLFLKEIIVPTNSNRYLFFIAPILAFAPAYAAWAVIPFSKGVVLSDMNLGLLYILAMTSFSIYGIVIAGWASNSKYSLFGALRAGAQVISYELAMGFAIVGVVIAAGSMGITGIIEAQSGGIWHWYFIPLFPLFIVYFIAGIAETNRAPFDVVEGESEIVAGHHIEYTGSRFALFFLAEYANMILISILTSIMFLGGWNSPFQATALESIFGFVPGVVWLFAKTGIFMFMFLWVRATYPRYRYDQIMRLGWKIFIPLTFVWVVIVACMVRLGVGPWW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: REX_STRZJ
Sequence: MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX10_CANGA
Sequence: MLVRTLYISSSVGSSNMLCNHGLKVIGKYSAIHEATRKIIVRSYSKETIKKHNKQAILNTAPIEFIANNSPLVGISDVNTIKEAAKRTLRCTDDVTDDQTDEIHPHLPFNVKPVDGKARAALKKEKNSMSLDIKKTMEAYVQLTKPRLTILVMLSAICSYALSPYPATVTELLCLTVGTTMCSGAANAINMGREPDYDRQMIRTQARPVVRGAVTPKQAFSFAFGMGTLGTSILYLGVNPTVAALGLSNIALYSWIYTSLKRKHIINTWVGALVGAIPPLMGWAAASPLTHPGSWCLAGLLYAWQFPHFNTLSHNIRNEYKNAGYVMTAWKNPLLNARVALRYSLLMFPLCFGLSYFNITDWYYQIDSGLVNAWLCLWSFKFYMQQRLNYSSKIKNDRVKFNEGLATANVYARKAFFASVLHLPAVLILAILHKKNRWDWLFEDSENPKLK
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PYRE_HAEIG
Sequence: MEQYKRDFIEFALSRNVLKFGEFTLKSGRKSPYFFNAGLFNTGADLARLGEFYAAAIQASAVDFDVVFGPAYKGIPIGTSVSVALFNRYGIDKPVCFNRKEVKDHGEGGNLIGSPLQGKILLVDDVITAGTAIRESMELISANKAELAAVLIALNRKERGKGELSAIQEVERDYQCQVLSIIDLDDLMQFIEQDPRYSSHLPEMRAYRAEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CTU2_CAEBR
Sequence: MNFNNFTSDLNGKTCVKCEKEAKFTGVDPKKAWYCQECFIQMVRNKFRSALSKKKIYKEADARDTLVVYDGSPSGTFLLNQIDDALKQITYKRLMVKPTVLVLVSESEEPEIQQVIKRVAEIKKNFLENVNWFIAHIAFCLYDEPSELKEFECNGIEKITAYKYLLASCSVPTYKKELERMLKEKCLQKLAESLKVTKCMVTDDADDLGRLALDQLCLGRGGSLSSLVTVAEKRNDFMIIRPLCDLSKREISIYNYLCKIDDHYIQFSHTQSQEKSVQTLTDAFIRTLEDEKFYSTINTVLSTASKIHNTNGKDGSRCSMCYVEVAEFQCETCSAVRNSCSENLNIIFS
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with tut-1/ctu-1 that ligates sulfur from thiocarboxylated urm-1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2, Thiolation of uridine in tRNA protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELMD1_HUMAN
Sequence: MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDVNPQLGISLQACLLQIVGYRNLIADVEKLRREAYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATAAQQVLSDSLHPKCRDITKEEISKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM
What is the function of this protein?
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
What are the official names of this protein?
ELMO domain-containing protein 1.
Protein: SYFA_CORDI
Sequence: MSEQPDYPAVELTEEGLAQAADAAIRAFGVASNLDELNIARRDHLGDAAPIPQARRSLGTLPKDQRKDAGRLVNMARGRLEKHFAQVKEVLEAKHLEEMLKAERVDVTVPTTRHQTGALHPITTLSEKIADIFVAMGYEVADGPEIEAEYFNFDSLNFIPDHPARTLQDTFHVGEPGSSQVLRTHTSPVQMRTMLSREVPIYVVCPGRVFRTDELDATHTPVFHQVEGLAVDKGLTMAHLRGTLDHLAKTLFGPETKTRMRANYFPFTEPSAEVDVWFPNKKGGAGWIEWGGCGMVNPNVLKAAGIDPEVYSGFAFGMGLERTLQFRNGLTDMRDMVEGDVRFTLPFGVQA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_AFIC5
Sequence: MNAPLKADDTDLAALMADLATKARAAARVLALAPAEQKNTGLAAMAAALRASAPKLLAANAEDVAEARASGATPAFVDRLALNDARIETMAAGLDVVRGLDDPVGKVTERWTRPNGMTIERVRVPLGVAAVIFESRPNVLADAGALCLKSGNAVILRGGSDSFRSCQAIHACLTQGLREAGLPEAAISLVPTRDRAAVGLLLSGLDGRIDVIVPRGGKSLVARVEAEARVPVFAHLDGNNHVFVDKAASLDMAKTIVLNAKMRRPGICGAAETLLVDKAAAPAQLKPLVGMLIDAGCEVRGDTDVQKADARVTPVTEDDWATEFEAPIIAAKVVGGLDEAIAHIERYGSHHTDAIVTDDATAATRFLNEVDSAIVLHNASTQFADGGEFGFGAEIGIATGKFHARGPVGVEQLTSFKYRVHGTGQTRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.