PharMolix/UniProtQA huggingface dataset:
Protein: FRMD6_HUMAN
Sequence: MNKLNFHNNRVMQDRRSVCIFLPNDESLNIIINVKILCHQLLVQVCDLLRLKDCHLFGLSVIQNNEHVYMELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFGPPMIIHFRVQYYVENGRLISDRAARYYYYWHLRKQVLHSQCVLREEAYFLLAAFALQADLGNFKRNKHYGKYFEPEAYFPSWVVSKRGKDYILKHIPNMHKDQFALTASEAHLKYIKEAVRLDDVAVHYYRLYKDKREIEASLTLGLTMRGIQIFQNLDEEKQLLYDFPWTNVGKLVFVGKKFEILPDGLPSARKLIYYTGCPMRSRHLLQLLSNSHRLYMNLQPVLRHIRKLEENEEKKQYRESYISDNLDLDMDQLEKRSRASGSSAGSMKHKRLSRHSTASHSSSHTSGIEADTKPRDTGPEDSYSSSAIHRKLKTCSSMTSHGSSHTSGVESGGKDRLEEDLQDDEIEMLVDDPRDLEQMNEESLEVSPDMCIYITEDMLMSRKLNGHSGLIVKEIGSSTSSSSETVVKLRGQSTDSLPQTICRKPKTSTDRHSLSLDDIRLYQKDFLRIAGLCQDTAQSYTFGCGHELDEEGLYCNSCLAQQCINIQDAFPVKRTSKYFSLDLTHDEVPEFVV
What are the official names of this protein?
FERM domain-containing protein 6, Willin.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Can colocalize with actin.
Protein: SCW11_YEAST
Sequence: MISPISFLSSLLCLTYLTSALPILPKREVVTRVHTASTTNVVTDFYSTTTEVVIAPTVEFLISDSVTFTTTLIPQGVNPTAEPTTTITKVLLKKAEMSTSSQPTSTLQPSTIPQSTSSFQAESTLQAVSTQQTAMSVSAGTSEDVQQLATTSTSISSSPSPTTTSTSTQNIVSGVGEANVEGNTQSQHHSYQAAATSTLNQQTSTSIASQESTESTNTPTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSTQETAATTSEGSSSSSAAITSSPKAIAYSPYNDDGSCKSADAVSSDLTLIKSKGISKIRVYGTDCNSFETVQPAAVKLGIKINQGLYITSSGVDSIDDSVTTLIQYGQTNGWDVFDFITVGNEAINNGWCSVSDLISKISSVKSKLSEAGYSGQITTSEPPVSFENNPDLCKKSDIDFVGINPHAYFDTSASAETAGTFVKGQVELIQGVCGTSNVFVTETGYPSSGIQNGGNIPSTANQITAVQNILNEMDLDVTILSTYNDYWKAPGDYGIEQSFGVIEYFP
What is the function of this protein?
Involved in cell separation.
What are the official names of this protein?
Probable family 17 glucosidase SCW11, Soluble cell wall protein 11.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ALKB7_MOUSE
Sequence: MAGSRRLAMRLLSGCAWVRGSDSAVLGRLRDEAVVHPGFLSQEEEDTLTRELEPQLRRRRYEYDHWDAAIHGFRETEKSCWSDASQVILQRVRAAAFGPDQSLLSPVHVLDLEPRGYIKPHVDSVKFCGSTIAGLSLLSPSVMKLVHTQEPEQWLELLLEPGSLYILRGSARYDFSHEILRDEESFFGEHRVPRGRRISVICRSLPEGMGPGRPEEPPPAC
What is the function of this protein?
May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate.  Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents.  Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death.  ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage.  Does not display DNA demethylase activity (By similarity).  Involved in fatty acid metabolism.
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial, Alkylated DNA repair protein alkB homolog 7.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LAA_XENLA
Sequence: MAENGDKEQKLDSDTKICEQIEYYFGDHNLPRDKFLKQQILLDDGWVPLETMIKFNRLSKLTTDFNTILQALKKSKTELLEINEEKCKIRRSPAKPLPELNDEYKNSLKHKSVYIKGFPTSAILDDVKEWLKDKGPIENIQMRRTLQREFKGSIFIIFNTDDDAKKFLENRNLKYKDNDMTVLSREEYHAKKNEERKLNKSEEKAKSKQVKKEAQKQAEDAERKLVEERVGSLLKFSGDLDNMTSREDLHALFQTHGDIEWIDFSRGAKEGIVLFKMNAKEALDKAKAANSDNLKLKGKDVKWELIEGDTEKEALKKILEGKQESFNKRKGRDGRKFKGKGRGGKGNDSSSRKRTQFQGKKKTFDSSDDEDDMEESESPQKASVKAEESAGTKNGAAAAPGSPKKRSLDDKAEDGPAVKQSKTEVGDQ
What is the function of this protein?
La protein plays a role in the transcription of RNA polymerase III.  It is most probably a transcription termination factor.  Binds to the 3' termini of virtually all nascent polymerase III transcripts (By similarity).
What are the official names of this protein?
Lupus La protein homolog A, La autoantigen homolog A, La ribonucleoprotein A.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRAZ_AGRFC
Sequence: MDRFLSNVTNRIDAKGRVSVPSPFRSVLARRDIQELYCLQDFAFPAISVGGPDLLERYERQIASMDAFSPEANAMSLLVHGGGVFMKLDQEGRLMVTDFVREFTGISTEVTFVGRADHFQLWQPNAFLAAQAEARAGRGFSAARPA
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CWP21_SOLLC
Sequence: ANAKVPSHTISNPF
What are the official names of this protein?
64 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SBI_STAAM
Sequence: MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNEKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYYNTYYKYKGAIDQTVLTVLGSGSKSYIQPLKVDDKNGYLAKSYAQVRNYVTESINTGKVLYTFYQNPTLVKTAIKAQETASSIKNTLSNLLSFWK
What is the function of this protein?
Plays a role in the inhibition of both the innate and adaptive immune responses.  Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH.  By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.
What are the official names of this protein?
Immunoglobulin-binding protein Sbi.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin-binding protein Sbi family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Occurs both extracellularly and associated with the cytoplasmic membrane where only the domains I and II are exposed to the extracellular media. Membrane association occurs via binding to lipoteichoic acid.
Protein: VATF_METJA
Sequence: MKVGVVGDRETAIGFRLAGLTDVYEVKNDEEAVKAINELANNENIAFIIITERIAESIKDKLKNINKVIVEIPDKHGKLERIDPVKELIRKAIGVSMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: DLDH_HAEIN
Sequence: MSKEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYSTLGGVCLNVGCIPSKALLHVAKVIEEAKHANKNGIYFSEPRIELDEVRAGKEAVVAKLTGGLAGMAKARKVTVVEGLATFTDSHTLVARDRDGNPTTVKFDNAIIAAGSRPVQLPFIPHEDPRIWDSTDALKLKEVPKKLLIMGGGIIGLEMGTVYNALGSEVEVVEMFDQVIPAADKDVVGIYTKQVEKKFKLMLETKVTAVEAKDDGIYVSMEGKACNDTKRYDAVLVAIGRVPNGKLIDAGKAGVEVDDRGFIHVDKQMRTNVPHIYAIGDIVGQPMLAHKGVHEGHVAAEVIAGQKHYFDPKVIPSIAYTEPEVAWVGKTEKECKQEGLNYEVAKFPWAASGRAIASECSEGMTKLIFDKDTHRVLGGAIVGSNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNAKAKEKIISI
What is the function of this protein?
Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y204_MYCPN
Sequence: MKEKTPFKNEKEFHEMVKKTKKGTFSGWYIIDKDNNSVEFSGKFNRQFKLNKPVITVNTEYVTRKELNEYKDSNDQRLTKIETTLAAQGEQINKLTQTVEKQGEQIRELQVEQKAQGEQIKAQGETLKLILQTLQKMSDRLDKIDPSK
What are the official names of this protein?
UPF0134 protein MPN_204.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: SYE_CHLPN
Sequence: MNWENVRVRVAPSPTGDPHVGTAYMALFNEIFAKRFKGKMILRIEDTDRTRSRQDYEENIFSALRWCGIQWDEGPDVGGPYGPYRQSERTKIYQGYVETLLKTDCAYKCFATPQELAEMRAVASTLGYRGGYDRRYRYLSPEEVASREAAGQPYTIRLKVPLSGECVFEDYSKGRVVFPWADVDDQVLVKSDGFPTYHFANVIDDHLMGITHVLRGEEWLSSTPKHLLLYEAFGWEPPVFLHMPLLLNPDGTKLSKRKNPTSIFYYRDSGYVKEAFVNFLTLMGYSMEGDEEVYSLERIIETFNPRRIGKSGAVFDIQKLDWMNKHYLNHEGSPECLLKELQGWLLNDEFFLKILPLCQSRITTLAEFINLTSFFFSGLLEYRVEELLPQALSPEKAAILLYSYVKYLEKTDQWTKETCYLGSKWLAQAFNVHHKKAIIPLLYVAITGKKQGLPLFDSIEILGKPRARARLVYAEKLLGGVPKKLAATVDKFMQREDFEEATFDL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBNA_STAA5
Sequence: MIEKSQACHDSLLDSVGQTPMVQLHQLFPKHEVFAKLEYMNPGGSMKDRPAKYIIEHGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANVEMVEEPDAHGGYLMTRIAKVQELLATIDDAYWINQYANELNWQSHYHGAGTEIVETIKQPIDYFVAPVSTTGSIMGMSRKIKEVHPNAQIVAVDAKGSVIFGDKPINRELPGIGASRVPEILNRSEINQVIHVDDYQSALGCRKLIDYEGIFAGGSTGSIIAAIEQLITSIEEGATIVTILPDRGDRYLDLVYSDTWLEKMKSRQGVKSE
What is the function of this protein?
Catalyzes the synthesis of N-((2S)-2-amino-2-carboxyethyl)-L-glutamate (ACEGA) from O-phospho-L-serine and L-glutamate.  Involved in the biosynthesis of L-2,3-diaminopropionic acid (L-Dap), a precursor of staphyloferrin B and antibiotics.
What are the official names of this protein?
N-(2-amino-2-carboxyethyl)-L-glutamate synthase, ACEGA synthase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.
Protein: Y1336_STAES
Sequence: MRINEMALHEKPRERLITYGAKSLSNVELLAILLNTGRKGFSSIDIANELLKQQSTIRDLKKLSINDLLKIKGIGLYKAVILQAAFELGERINSTSTFDKVQITHPSDVASLMMSTMKDLEQEHFVVLLLNSKNIVTKQAWVYKGTLNSSIIHPREVFNIAIRESSNSIIVVHNHPSGDVTPSKEDITTTYRLKECGDILGINLLDHIIIGDNKFTSLVEAGYFDK
What are the official names of this protein?
UPF0758 protein SE_1336.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: SCAF_HCMVA
Sequence: MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVEPPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASPAVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGAPVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDEPPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARKRLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASSSPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGPSTAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Protease precursor, pPR.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: LPXH_PSEP1
Sequence: MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCDAAGCTLLSDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSARYKLARKLRSESRTQVRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLVVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PEPE_SALPB
Sequence: MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQTWDEYTDKTAEVLAPLGVNVTGIHRVADPLAAIEKAEIIIVGGGNTFQLLKESRERGLLAPVADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALDLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGEEAVALEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUC_RICCN
Sequence: MIIDVNTPISSRLDKYLKRLYPLLTQGVIEKALRQKQITVNAQKAEASLRVKGGDKIFINDKFNLPVKQPEKLVFTDAEIKLAKKITTDYLIYADDNLIAINKPAGLATQGGTKINLSIDSALKYLNYKGADFKLVHRLDKKTSGLLLIAKNYLSSVKLHNAFKEKLVVKTYFAVTYGKPIKNVGEVRSNIEKSKGSTPKITDIDSENGKLAITYYKVLKSLDNNLFLIEFTPVTGRMHQLRLHAKLLGCPILGDDKYGNKEIMPYSKYMFLHANNICLSEKIFGQESKLEAKLPFYFTRRLT
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase C, 23S rRNA pseudouridine(955/2504/2580) synthase, rRNA pseudouridylate synthase C, rRNA-uridine isomerase C.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: GMHA_YERPG
Sequence: MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHLSCVSNDFGYDYVFSRYVEAVGREGDVLLGISTSGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_CHLL2
Sequence: MDASDRSMAVKRMEMVQSLRQKGLVNERVLDAMQRIERHRFVDRESSVSAYEDSAYPIGYGQTISQPYTVAYMTTLLLERCPPPGKVLEIGTGSGYQAAILDALGYRVYSVERIPELHDRVVGLFRSLGLAISCRVGDGSLGWEEEAPFDGIMVTAAAPRCPEHLLEQLGDNGCLVIPVGEHNMQQMTVYRRVGERFEKELFHHFAFVPLIGREGWN
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_STAAT
Sequence: MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNEDNIDVAFVPGAFEIPLVAKKLASSGNYDAVITLGCVIRGATSHYDYVCNEVAKGVSKVNDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SYP_GEOSM
Sequence: MRYSQYFIPTVKETPSDAEVISHKLMLRAGMIRKLAAGIYNYLPFGLRSIRKVEAIVREEMNRAGAIELLMPAVQPAELWKESGRWEFYGKELLRFNDRKDAEFCMGPTHEEVITDLIRKEVRSYRQLPINLYQIQGKFRDEIRPRFGLMRGREFIMKDAYSFDVNEAGADVSYEKMYKAYRRIFERCGLKFRAVEADTGTIGGNYSHEFMVLADSGEDAIVSCSACEYAANMEKAETRKGEGIEHADPRPMEHVSTPGQKSIEDVAAFLGVQNTQVVKTLVLVADGEPVVALIRGDYDLNEIKLKNHLGCAELEMAEDDVVVKVTGAPTGYAGPVGLAAKVKVVADLSLEGMHNFVTGANAADTHLKNVNIGRDFSVSGFVDIRNVVIGDACPRCDSGKLEIWRGIEVGHVFKLGTKYSKALKATFLDADGKEQTIFMGCYGIGVGRTVAACIEQNHDENGIIFPIPIAPFQCIISSLSVKEDEVKAASESIYQELLEAGIEVLLDDRDERPGFKFKDADLIGIPLRIVVGAKALAEGKVELKERRSGEVEVLPIAEAIAKVKAAVKEALQV
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_ACIBT
Sequence: MRKDIHPAYQQVLFHDTNADVYFLIGSTIQTKQTKEYQGQVYPYVTLDISSASHPFYTGEVRQASNEGRVASFNKRFARFNRKS
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: TGT_BACP2
Sequence: MSQLPIRYEFIKSCKQTGARLGRVHTPHGSFDTPVFMPVGTLATVKTMAPEELKAMEAGIILSNTYHLWLRPGHDIVKEAGGLHKFMNWDRAILTDSGGFQVFSLSEFRKIEEEGVHFRNHLNGDKLFLSPEKAMDIQNALGSDIMMAFDECPPYPAEYDYMKRSVERTSRWAERCLTAHQRPEDQGLFGIIQGGEYEELRKQSAKDLVSLDFPGYAIGGLSVGEPKDVMNRVLEFTTPLLPADKPRYLMGVGSPDSLIDGAIRGVDMFDCVLPTRIARNGTLMTSEGRLVVKNAKYERDFRPIDENCDCYTCKNYTRAYIRHLIKTNETFGIRLTTYHNLHFLLKLMEQVREAIREDRLGDFKEEFFERYGFNEPNAKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: NUOK_BEUC1
Sequence: MTLVNYLVLSGLLFTIGAATVLVRRNAIIMFMGVELMLNASNLAFVAFGRLHGTLTGEVVAFFVMVVAAAEVVVGLAIIVSIYRARRSVSVDELSLLKN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYN_STAHJ
Sequence: MKTTIKQAKQHLNQEVTIGAWLTNKRSSGKIAFLQLRDGSGFMQGVVVKSEVSDETFQLAKEITQESSLYVTGVITEDNRSDLGYEMQVKSIEVIHEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEIIRATYEFFNENGFTKIDPPILTASAPEGTSELFHTKYFDEDAFLSQSGQLYMEAAAMAHGRVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFTNHVESLEVQEQYVSHVVKSVLKNCQLELKALDRDTSKLEKVSAPFPRISYDDAIKFLKEEGFNDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERINDLELLEQRIDEHQLDAESYNYYLDLRRYGSVPHSGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSD_PYRAB
Sequence: MRIPEDVRKDIPLTQEVIYFDNTATSLTPKPVIEAMDEYYLRYRANVHRGVHRLSQMATQKYEESRKVVADFINAEFDEIAFTKNTSESLNLVALGLEHLFKKGDKIVTTPYEHHSNLLPWQRLAKKKGLKLEFIEGDDEGNLDLADAEKKIKGAKLVAVQHVSNALGVIHEVEELGKMVKEEGAIFVVDAAQSVGHMEVDVKKLKADFLAFSGHKGPMGPTGIGVLYINKEFFDVFEPPLIGGGTIEDVELCCYKLTEPPERFEAGTPNIGGAIGLAAGIKYIEKIGIDKIEKQERKLVKRTTEGLDELEIPWYGPRNLDKHAGVVSFNVPPLHPHDVASVLDEHKIMVRSGHHCALPVMKRLKINGTVRASFHVYNSLEEVETFLGVLEELVKSLRSSQ
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: VA721_ARATH
Sequence: MAQQSLIYSFVARGTVILVEFTDFKGNFTSIAAQCLQKLPSSNNKFTYNCDGHTFNYLVEDGFTYCVVAVDSAGRQIPMSFLERVKEDFNKRYGGGKAATAQANSLNKEFGSKLKEHMQYCMDHPDEISKLAKVKAQVSEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDFRTTGTQMRRKMWLQNMKIKLIVLAIIIALILIIVLSVCHGFKC
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
What are the official names of this protein?
Vesicle-associated membrane protein 721, AtVAMP721, v-SNARE synaptobrevin 7B, AtVAMP7B.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein. Early endosome membrane; Single-pass type IV membrane protein.
Protein: NCED6_ARATH
Sequence: MQHSLRSDLLPTKTSPRSHLLPQPKNANISRRILINPFKIPTLPDLTSPVPSPVKLKPTYPNLNLLQKLAATMLDKIESSIVIPMEQNRPLPKPTDPAVQLSGNFAPVNECPVQNGLEVVGQIPSCLKGVYIRNGANPMFPPLAGHHLFDGDGMIHAVSIGFDNQVSYSCRYTKTNRLVQETALGRSVFPKPIGELHGHSGLARLALFTARAGIGLVDGTRGMGVANAGVVFFNGRLLAMSEDDLPYQVKIDGQGDLETIGRFGFDDQIDSSVIAHPKVDATTGDLHTLSYNVLKKPHLRYLKFNTCGKKTRDVEITLPEPTMIHDFAITENFVVIPDQQMVFKLSEMIRGGSPVIYVKEKMARFGVLSKQDLTGSDINWVDVPDCFCFHLWNAWEERTEEGDPVIVVIGSCMSPPDTIFSESGEPTRVELSEIRLNMRTKESNRKVIVTGVNLEAGHINRSYVGRKSQFVYIAIADPWPKCSGIAKVDIQNGTVSEFNYGPSRFGGEPCFVPEGEGEEDKGYVMGFVRDEEKDESEFVVVDATDMKQVAAVRLPERVPYGFHGTFVSENQLKEQVF
What is the function of this protein?
Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity.  Catalyzes the first step of abscisic-acid biosynthesis from carotenoids.  Contributes probably to abscisic acid synthesis for the induction of seed dormancy.
What are the official names of this protein?
9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic, AtNCED6.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Note=Partially bound to the thylakoid.