PharMolix/UniProtQA huggingface dataset:
Protein: SSB1_ASHGO
Sequence: MAEGVFSGAIGIDLGTTYSCVATYESSVEIIANEQGNRVTPSFVAFTPEERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQSDMKTWPFKVIDANGSPMIEVEYLGETKSFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLGAGKSEKERHVLIFDLGGGTFDVSLLNIAGGVYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISGDARALRRLRTAAERAKRTLSSVTQTTVEVDSLFEGEDFETSITRARFEDINAALFKSTLEPVEQVLKDAQISKSQIDEVVLVGGSTRIPKVQKLLSDFFEGKQLEKSINPDEAVAYGAAVQAAILTGSNLSDDTKDLLLLDVAPLSLGVAMQGDVFACVIPRNTTVPTIKRRTFTTVHDGQTTVTFPVYQGERVNCKDNTLLGEFDLKGIPPLPAGEPVLEAIFEVDANGILKVTAVEKSTGKTANITISNAIGRLSSEDIEKMVSQAEEFKAADEAFAKRHEARQRLESYVSSIEQTVSDPVLSAKMKKGAKSKVEAALADAFSALQIEESSAEDYRKAEIGLKRVVTKAMATR
What is the function of this protein?
Ribosome-bound, Hsp70-type chaperone that assists in the cotranslational folding of newly synthesized proteins in the cytosol.  Stimulates folding by interacting with nascent chains, binding to short, largely hydrophobic sequences exposed by unfolded proteins, thereby stabilizing longer, more slowly translated, and aggregation-prone nascent polypeptides and domains that cannot fold stably until fully synthesized.  The Hsp70-protein substrate interaction depends on ATP-binding and on allosteric regulation between the NBD and the SBD.  The ATP-bound state is characterized by a fast exchange rate of substrate (low affinity state), while in the ADP-bound state exchange is much slower (high affinity state).  During the Hsp70 cycle, the chaperone switches between the ATP-bound state (open conformation) and the ADP-bound state (closed conformation) by major conformational rearrangements involving mainly the lid domain.  Ssb cooperates with a specific Hsp40/Hsp70 co-chaperone termed the ribosome-associated complex (RAC), which stimulates the ATPase activity of the ribosome-associated pool of Ssbs and switches it to the high affinity substrate binding state.  Hsp110 chaperone SSE1 and FES1 act as nucleotide exchange factors that cause substrate release.
What are the official names of this protein?
Ribosome-associated molecular chaperone SSB1, Heat shock protein SSB1, Hsp70 chaperone Ssb.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family. Ssb-type Hsp70 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with translating ribosomes.
Protein: Y8251_ORYSJ
Sequence: MGTWCERCRRRDEQDYRNLDDCQKHFLLLMMGDFQHEIRGEQIVEQLTIPKEFVQRLKGDIPEEIQLETHNRNSYTVRVDKSQEKVIFAAGWAQFVKTFDLHMGDSMMFRFKGNSQFDVIIFDQVGREKVCSVAVDDYLDPNVQEGRTDATETLNSSRAHSQDDYLDPNVQEGRTNATETLNSSRAHSQPMPMQTPATETLNSSRAHSQDMPMQSPATETLNSSRAHPQPMPMQLPTETVNHFHAPHYPMQMPIENMALSRTQAMPTQMQSPPTYRWTQVQRDNLRYSLPSEDQGCRVGVIPDPIIGRRTKLNPVQEKVVNFKIQHIHSEIPIFVAVIKRSNVSGVLSTLSVAKRYVDEYLGGERFISLSRLGGKWGIRLLLVGVGVAQGW
What are the official names of this protein?
Putative B3 domain-containing protein Os08g0325100.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOD_CHRVO
Sequence: MAEIRNYTLNFGPQHPAAHGVLRLVLELDGEVVQRADPHIGLLHRGTEKLAESKTFIQSLPYMDRLDYVSMMCNEHAYCLAIEKMMGIEVPERAQYIRVMFAEITRILNHLLWIGAHALDIGAMTMFLYAFREREDLMDCYEAVSGARMHAAYFRPGGVYRDLPDSMPQYTVSKIKNAKELARLNEGRKGSMLDFIEDFTKRFPTYVDEYETLLTDNRIWKQRTVGIGVVTPERALNLGMTGPMLRGSGIAWDLRKTQPYDVYDKMDFDVPVGVGGDCYDRYLVRVEEMRQSNRIIQQCVAWLRANPGPVITDNHKVAPPSREGMKSNMEDLIHHFKLFTEGMHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLAALDEMATGHMIADVVAIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PATE_PENEN
Sequence: MRLTSGIFHAAIAVAAVGAVLPEGPSSSKTHRNEYARRMLGSSFGIPKNQTFDYLVIGGGTAGLTIATRLAEQGVGSVAVIEAGGFYELNNGNLSQIPAQDAFYVGTDLDDWQPGIDWGFHTTPQAGAYDRVSHYARGKCLGGSSARNYMAYQRGTKAAHQRWADTVGDSSYTWEQFLPFFEKSLHFTPANDALRGANASVVSDPSVLGNGDGPLSVTYPHYAQAFATWAKHAFIEIGLQIRSGFQSGALLGQSYGLYTINATTMHRESSETSFLRKGLADPNLTVFQSALAKRIRFQDKRAVGVDVETMGRAYTLSARKEIVLSAGAFQSPQLLMVSGVGPAATLKAHNIPLVADRPGVGQNMQDHIIYAPSYRVNVITQSALLNEEFEAQANRDYNERAAGIYANPTSDILAWEKIPEPKRSAWFSNHTRQVLAEYPDDWPEVEFLTMGGYFGYQRNYIRDNPSDGYNYASLAVSLCTPRSRGNVTITSPDAGVPPVINPNWLTDPVDVELAVAAFKRTRDFFNTTAIKPILIGPEYFPGSQVATDAEILDHVRKSFDTIFHASCTCAMGLANDTQAVVDSKARVIGVEALRVVDASALPFLPPGHPQSTLYALAEKIACEISGNC
What is the function of this protein?
Patulin synthase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria (PubMed:30100914, PubMed:25625822, PubMed:30680886).  PatE catalyzes the last step of the pathway which is the conversion of E-ascladiol to patulin (PubMed:30680886).  The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units.  The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol).  These first reactions occur in the cytosol.  The intermediate m-cresol is then transported into the endoplasmic reticulum where the cytochrome P450 monooxygenase patH converts it to m-hydroxybenzyl alcohol, which is further converted to gentisyl alcohol by the cytochrome P450 monooxygenase patI.  The oxidoreductases patJ and patO further convert gentisyl alcohol to isoepoxydon in the vacuole.  PatN catalyzes then the transformation of isoepoxydon into phyllostine.  The cluster protein patF is responsible for the conversion from phyllostine to neopatulin whereas the alcohol dehydrogenase patD converts neopatulin to E-ascladiol.  The steps between isoepoxydon and E-ascladiol occur in the cytosol, and E-ascladiol is probably secreted to the extracellular space by one of the cluster-specific transporters patC or patM.  Finally, the secreted patulin synthase patE catalyzes the conversion of E-ascladiol to patulin (PubMed:30680886) (Probable).
What are the official names of this protein?
Patulin synthase, Dehydrogenase patE, Patulin biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Vacuole. Secreted. Secreted, cell wall.
Protein: JAMYB_ORYSJ
Sequence: MEMVLQRTSHHPVPGEQQEAAAELSSAELRRGPWTVDEDLTLINYISDHGEGRWNALARAAGLKRTGKSCRLRWLNYLRPDVKRGNFTAEEQLLILDLHSRWGNRWSKIAQHLPGRTDNEIKNYWRTRVQKHAKQLNCDVNSKRFKDAMKYLWMPRLAERIHARAGAVDDSGDYSNNDLSCVSGVTMATVANCFDGSPSMVTSSSSDSFTSESQDLKKINLHVHGDDEKMNSEDWMQEVDHEFWSTEIQPNNEQFQDQQLNGWVQGFSEGLSETLWSLEDIWKMQ
What is the function of this protein?
Probable transcription factor that may be involved in the jasmonate-dependent defense responses to the rice blast fungus Magnaporthe oryzae.  Does not seem to function in the salicylic acid-dependent signaling pathway.
What are the official names of this protein?
Transcription factor JAMYB, OsJAMyb.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYP6_RHIO9
Sequence: MAAKNLPKVFFDIAVNGQHSGRMTFKLFSDTVPKTAENFRALCTGEKGKGISGKPLHYKNSYFHRIIPGFMAQGGDFTMGDGRGGESIYGRTFKDENFTLKHKGKGLLSMANAGPNTNGSQFFITFVDTPWLDGNHTVFGQIVDGSKVLDLLEQHGSRSGMPSAKIEITDCGELKD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase cyp6, PPIase cyp6, Cyclophilin cyp6, Rotamase cyp6.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: DXS1_JANSC
Sequence: MSDRPSTPLLDNVQSPNDLKGLSDFDLKRLADELRAEMIWTVSKTGGHFGAGLGVVELTVALHSVFDTPRDKLVWDVSHQCYPHKILTGRRDQMLTIRQKDGLSGFTKRSESPFDPFGAAHSSTSISAALGFAVARDLGGDSDTGHGDAIAVIGDGAMSGGMAFEAMNNAGHLGKRLIVILNDNEMSIAPPTGALSSYLSRLYAGAPFQEFKAAAKGAVSLLPEPFQEGARRAKELLKSATVGGTLFEELGFSYVGPIDGHDMESLLSVLRTVKARADGPILIHAITKKGKGYSEHRADRGHATAKFNIATGEQVKAPSNAPSYTKVFAQSLIAEAEDDPKVVAVTAAMPDGTGLDLFAERFPSRCFDVGIAEQHGVTFAAGMAAGGLKPFAAIYSTFLQRGYDQVVHDVAIQRLPVRFAIDRAGLVGADGCTHAGSYDISYLANLPGFVVMAAADEAELRHMVRTALEIDDRPSAFRFPRGEGMGVDMPDRGTALEIGKGRMISEGNRVAILNFGTRLKEVQEAAETLSQRGITPTIADARFAKPLDEALILQLARHHEALITVEEGAVGGFGSHVAHLLAENAVFDTGIKYRSMVLPDIFIDQASPKDMYAVAGMNAEDIVAKVLTTLGVEVLSQRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase 1, 1-deoxyxylulose-5-phosphate synthase 1, DXP synthase 1, DXPS 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: POLG_DEN2D
Sequence: MNNQRKKARSTPFNMLRRERNRVSTVQQLTKRFSLGMLQGRGPLKLFMALVALPRFLTIPPTAGILKRWGTIKKSKAINDVRGCRKEIGRMLNILNRRRRTAGVIIMLIPTVMAFHLTTRNGEPHMIVSRQEKGKSLLFKTEDGVNMCTLMAIDFGELCEDTITYKCPLLRQNEPEDIDCWCNSTSTWVTYGTRTTTGEHGREKRSVALVPHVGMGLETGTETWMSSDGAWKRACRMETWILRHPGFTIMAAILAYTIGTTHFQRGLILILQTAVAPSMTMRCIGISNRDFVEGVSGGSWVDIVLEHGSCVTTMAKNKPTLDFELIKTEATQPATLRKYCIEAKLTNTTTESRCPTQGEPSLNEEQDKRFVCKHSMVDRGWGNGCGLFGKGGIVTCAMFTCKKNMEGNIVQPENLEYTIVITPHSGEEHAVGNDTGKHGKEIKITPQSSITEAELTGYGTVTMECSPRTGLDFNEIVLLQMEDKAWLVHRQWFLDLPLPWLPGADTQGSNRIQKETLVTFKNPHAKKQDVVVLGSQEGAMHTALTGATEIQMSSGNLLFTGHLKCRLRMDKLQLKGMSYSMCTGKFQIVKEIAETQHGTIVIRVQYEGDGSPCKIPLEIMDLEKRHVLGRLITVNPIVTEKDSPVNIEAEPPFGDSYIIIGVEPGQLKLHWFKKGSSIGQMFETTMRGAKRMAILGDTAWDFGSLGGVFTSIGKALHQVFGAIYGAAFSGVSWTMKILIGVIITWIGMNSRSTSLSVSLVLVGVITLYLGAMVQADSGCVVSWKNKELKCGSGIFITDNVHTWTEQYNFQPESPSKLASAMRKAHEEGICGIRSVTRLENLMWKQITPELKHILSEIEVKLTIMTGDIKGIMQAGTRSLRPQPTELKFSWETWRKAKMVPTEPHNQTFLIDGPETAECPNTNRAWNSLEVEDYGFGVFTTNIWLKLREKEDLCCDSKVMSAASKDNRAVHDDMGYWIESALNDTWKMEKASFIEVKSCHWPKSHTLWINGGLESEMIIPKSFAGPVSQHNYRPGYYTQTAGPRHLGKLEMDFDFCEGTTVVVTEDCGNRGPSLRTTTASGKLITEWCCRSSTIPPLRIKGEDGCWYGMEIRPLKEKEENLVTSLVTA
What is the function of this protein?
Disrupts the host endothelial glycocalyx layer of host pulmonary microvascular endothelial cells, inducing degradation of sialic acid and shedding of heparan sulfate proteoglycans.  NS1 induces expression of sialidases, heparanase, and activates cathepsin L, which activates heparanase via enzymatic cleavage.  These effects are probably linked to the endothelial hyperpermeability observed in severe dengue disease.
What are the official names of this protein?
Genome polyprotein.
What are the subcellular locations of this protein?
[Capsid protein C]: Virion. Host nucleus. Host cytoplasm. Host cytoplasm, host perinuclear region. SUBCELLULAR LOCATION: [Peptide pr]: Secreted. SUBCELLULAR LOCATION: [Small envelope protein M]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Envelope protein E]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Non-structural protein 1]: Secreted. Host endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Note=Located in RE-derived vesicles hosting the replication complex.
Protein: SELU_ECOK1
Sequence: MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELSQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: P5CR_CORGL
Sequence: MTTIAVIGGGQIGEALVSGLIAANMNPQNIRVTNRSEERGQELRDRYGILNMTDNSQAADEADVVFLCVKPKFIVEVLSEITGTLDNNSAQSVVVSMAAGISIAAMEESASAGLPVVRVMPNTPMLVGKGMSTVTKGRYVDAEQLEQVKDLLSTVGDVLEVAESDIDAVTAMSGSSPAYLFLVTEALIEAGVNLGLPRATAKKLAVASFEGAATMMKETGKEPSELRAGVSSPAGTTVAAIRELEESGIRGAFYRAAQACADRSEELGKR
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF300_RAT
Sequence: MATGEPRDRGGYYFRFLPQRTFSSLSAREITNRLRQWSMLGRIQAQAFGFDQTFQPYQKDDFVTAFFKDPNVIPHLQLLAESSGQWTTLGTEVKRIEAINVPCTQLSMSFFQRLYDENIVRESGHIVKCLDSFCDPFLISDELRKVLLMEDSEKYEVFSPVEREEFLFCLFKHLCLGGSLCQYEDVLKPYLETAKLIYKDLVSVRKHPRTKEIQITSSVFKVKAYDSLGVCYPSPKEHEQTFSYFVVDPIKRHVNVLYHCYGVGEMA
What is the function of this protein?
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility.  May play a role in outer and inner dynein arm assembly.
What are the official names of this protein?
Cilia- and flagella-associated protein 300.
What is the protein family that this protein belongs to?
Belongs to the CFAP300 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme.
Protein: WDY_DROVI
Sequence: MSLVYFASGDSKADIEYQTISSTATQVSQEQSERLHDRISKAQLQKLYELFKSAPGQVVGCGDLRRMLEDVDITFNDFAYTRLFLKINQNHDFMVDWNEFVSYLIFGFQEEDPSSQKEALIMPISMAPVVRKTEHRSAVCCITLLKVKSDQTPMEEITESANYSFGGEDSPENSGMWVTASHEGQLRFWSAHMEPLRSAVSESIYCMSYAFYNNGKTHSKLVLGDYAGNVRILSYSPYLRGPFQAKPGAALVELVWADVLRGRIPLLIPREYINLHNELISCVYFSLHMNTLFASAEYRNTKKYRGRCPGLIMVSNEDRNNFRIPLGVSVFYVSEIKNILVTGGPDTFVRIWDVYISSEPSAILTGHNGGIVAVFVQPEENKVYSVDYHKIIKVWDLQEHTLLQTYGDLVRIIHHSETDIKYYYHSHLRELMVAGRKLIQIKCCPRVRVDLTDGNTHAAPVSVVLYNRLFRNIVTCGLDSYIIVWDPWTGRRKIIMKNCHTKMIYGETIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNAVVVRNMSIQPDQEVTAVIWVVDRILAMGWDRQVTEFNDVEGREYGDPKKWAKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYNVMDPSRFIELKLNAEEEKLTRRSKRMSSLIGVNRRSTSVQAIKPDEIKDYGANIPVSVQAVLFLQRRPMTKEHGSVFISLDTGIIQVYSHHQHGGYIKQFTAVHKTGDCVLTMATDRKNRFLYTGTAFGYIKVWHIVNYCIPKAEQTYVCMPRLRLEFIFLRKELFLTRAKRMVRFQPEPMLVSSYKGHLKAINSIGFINLPKIIFSGSHDYSCRLWTQGGRYLGTLGTVLPWSKLTPFERAGEDNRAYRLPPDIKKVASSTTLKVISGIQHSFTLKRPKAAEEREEEREVEDTTTDVKNMFERPLREPILGKHFQLPGRSAIEQRIELDTTQLYIPVYTHLRVYPSEMLEALPTSPIISQVKAENYLDHYMPVVGKVDLNTSAINIKEPQKLARTKAGANLDQPRASAGWAKPKTNSILGIPRAGSSLGKARASVSQGSPKAGVSSGYGKVSVSQGYPRAGSPRPCTTSLSKPKTSSSPSKPKGSFRLGSPIAATSPANADSSPGKRKSSPGKRSFSPGKAKASPGKARISSVLGKPKAKTDRETH
What are the official names of this protein?
WD repeat-containing protein on Y chromosome, WD40 Y.
Protein: PURL_MYCTU
Sequence: MSPLARTPRKTSVLDTVEHAATTPDQPQPYGELGLKDDEYRRIRQILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEMRAAMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVCRKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADRSAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGMLRIDESTGRGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQVTADHLGGLPPVVDLAREKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAGETGCRIVLPEGADPFVLLFSESAGRVLVAVPRTEESRFRGMCEARGLPAVRIGVVDQGSDAVEVQGLFAVSLAELRATSEAVLPRYFG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_UREP2
Sequence: MSTIVALATAPMNCAIHIIRVSGPKAFEIINKISTIKIKKETFKIWYTILKDDNQILDEVLINTFVAPKTFTGEDLVEINCHGGIVVANLIIKTLIKYGCQPAQRGEFSRRALLNKKMDLSKIEAINNLVNAKNELSVKGVIGALLGRVSQSIAEFRHELFMIIGQIEVNIDYPEYDDVEQVDAIILKQRLLSLDKKITKIIDQSKKFLPINKGIRVLIIGKPNVGKSTLLNALCNEQKAIVTDIPGTTRDVIESSINIDNITLNILDTAGIHLTNDFVENLGINKAKALIDKVDLILYLIPANEQQDLELYDLIKKQKHLLVYTKKDLVDQYDDKQIYINAKNNDIQSLIDEIKKLFYVQEFDNANIDVLQSQRQIGILENVHYLINNAILNLEKGDTLDLIVADLEFCNLRLNELLGISSEYDFLDDLFKNFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_DESVM
Sequence: MPRQEHIRNFSIIAHIDHGKSTLADRILEVTGLVSDREKRDQYLDRMELERERGITIKAQSVRIPYTAKDGRKYVLNLIDTPGHVDFNYEVSRSLAACEGALLVVDASQGVEAQTLANVYLALDHNLEVIPVLNKVDLPSADADRVKHEIEESIGLDCSDAVAVSAKTGLNVDKVLEAIVERLPAPEGNLNAPLKALIFDSWYDSYQGVVVLFRIVDGVLRKGDRIKLFATERSYEVIRLGVFSPEIVDMTELGAGEVGFLCANIKELGDAKVGDTITHVDRPAEVPVEGFKEVQPMVFCGLYPTDSADYEQLKYALEKLQLNDAAFSYEPETSQALGFGYRCGFLGLLHMEIIQERLEREFQVELIATAPSVIYKIDTVDGKKSDIDNPSKLPDPTKIAALYEPYVRMDIHVPNDYVGNVLKLCEEKRGIQKNMGYIASNRVVITYELPFAEIVFDFFDRLKSGTKGYASMDYEFIDYRQSALVKLDILINGEAVDALAVIVHRDKAYHYGRALALKLKRTIPRQMFEVAIQAAIGQKIIARESISALRKNVTAKCYGGDITRKRKLLEKQKEGKKRMKRMGNVELPQEAFLAALQVGDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BGLC_EMENI
Sequence: MRVDSTVLALVALATDCLGLAIKSNEPELLRRDALPIYKNASYCVDERVRDLLSRMTLEEKAGQLFHKQLSEGPLDDDSSGNSTETMIGKKHMTHFNLASDITNATQTAEFINLIQKRALQTRLGIPITISTDPRHSFTENVGTGFQAGVFSQWPESLGLAALRDPQLVREFAEVAREEYLAVGIRAALHPQVDLSTEPRWARISGTWGENSTLTSELIVEYIKGFQGEGKLGPKSVKTVTKHFPGGGPMENGEDSHFYYGKNQTYPGNNIDEHLIPFKAALAAGATEIMPYYSRPIGTNWEAVGFSFNKEIVTDLLRGELGFDGIVLTDWGLITDTYIGNQYMPARAWGVEYLSELQRAARILDAGCDQFGGEERPELIVQLVREGTISEDRIDVSVARLLKEKFLLGLFDNPFVNASAANNIVGNEHFVNLGRDAQRRSYTLLTNNQTILPLAKPGEGTRFYIEGFDSAFMSARNYTVVNTTEEADFALLRYNAPYEPRNGTFEANFHAGSLAFNATEKARQAKIYSSLPTIVDIILDRPAVIPEVVEQAQAVLASYGSDSEAFLDVVFGVSKPEGKLPFDLPRSMDAVEAQAEDLPFDTENPVFRYGHGLEYEDN
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose.
What are the official names of this protein?
Beta-glucosidase C, Beta-D-glucoside glucohydrolase C, Cellobiase C, Gentiobiase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROF_SALTI
Sequence: MQKDALNNVRITDEQVLMTPEQLKAAFPLSLAQEAQIAQSRGIISDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTTVGWKGLINDPHMDGSFDVEAGLKIARQLLVELVNMGLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQVALLQTQGNPHGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDYRRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWEMTDALLREIHKDLSGQLAVRVA
What is the function of this protein?
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-I DAHP synthase family.
Protein: TTCA_SHESM
Sequence: MPEELSKKQITRLNKLQKRLRREVGSAIADYNMIEDGDRVMCCLSGGKDSYAMLDILLNLQQRAPVQFEIIAVNLDQKQPGFPEHVLPAYLDSLNIPYHILEKDTYSIVKEKIPEGKTTCSLCSRLRRGTLYGFAQRIGATKIALGHHRDDIIETMFLNMFYGGKMKAMPPKLLSDDGANVVIRPLAYCREKDLEEYAELKKFPIIPCNLCGSQENLKRQAVKDMLNQWDRLYPGRIETIFTAMQNTAPSQGVDREQFDFVSLKRDPNAPMKGDVAEADLPAFDFLDIANSGHIDLDAAKRINIVNVYEA
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_RICRS
Sequence: MKNNFYQEDELLSNELSNRGFLLTKVDDVIGWARANSLWPMTFGLACCAVEMMQAAASRYDMDRFGMLFRPSPRQSDLMIVAGTLTNKMAPALRKVYDQMAEPKWVLSMGSCANGGGYYHFSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGLMQLQKKIKRTTGFKYDARQTH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.