PharMolix/UniProtQA huggingface dataset:
Protein: GRL1A_PONAB
Sequence: MCSLPRGFEPQVPEDLERRSLAELREMLKRQERLLRNEKFICKLPDKGKKIFDSFAKLKAAIAECEEVRRKSELCHPVSLDCKLRQKAIAEVDVGTDKAQNSDPILDTSSLVPGCSSVDNIKSSQTSQNQGLGRPTLEGDEETSEVEYSVNKGPASSNRDRVPPSSEASEYHLQHRVSSQAEDTSSSFDNLFIDRLQRITIADQGEQQSENASTKNLTGLSSGTQKKPHYMEVLEMRAKNPVPQLHKFKTNVLPFRQNDSSSHCQKSRSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQRKQKYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDEDDDWSSDEF
What is the function of this protein?
Appears to be stable component of the Pol II(G) complex form of RNA polymerase II.  Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery.  May play a role in Mediator-dependent regulation of transcription activation.  In vitro, acts as negative regulator of transcriptional activation; this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a level equivalent to that of Pol II (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit M, Glutamate receptor-like protein 1A.
What is the protein family that this protein belongs to?
Belongs to the GRINL1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUC_SALSV
Sequence: MAKTLYEKLFDAHVVFEAPNETPLLYIDRHLVHEVTSPQAFDGLRAHHRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCNEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVTGNAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGRDFDEAVEYWKTLKTDDGATFDTVVTLRAEEIAPQVTWGTNPGQVISVTDIIPDPASFSDPVERASAEKALAYMGLQPGVPLTDVAIDKVFIGSCTNSRIEDLRAAAEVAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRSIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: YIDD_LACP3
Sequence: MKQVLTWLVRGYQRFISPLLPPSCRYYPTCSTYMIQALQKHGAIKGSLMGIARILRCNPFVKGGLDPVPAFFTLRRNPHPENDLDLSDIQNLNHKLGGRHG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS10_DICDI
Sequence: MPLIPTENKLAIYRYLFQEGVLVAPKDFHLAKHPQIETVSNLDVLQILRSFKSRKFVTETFNWQYYYWVLTEEGIKYLRTYLQVPESVVPATMKKQASRPSTYTRSEETKRTGASGDFDPSFNRGDRRQGGDRRGGMGRGQYRTERSAPAPQQN
What are the official names of this protein?
40S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPNP2_ARATH
Sequence: MSYEKELAAAKKAVTLAARLSQEVQKTLLQSQVWKKSDRSPVTAADYGSQAVVSLVLERELQPDKLSLVAEEETGDLRKNGSEAFLEDIAKLVKDTLASEESYTSSPLSTDDVLNAIDCGKSEGGCKGSHWVLDPIDGTRGFVRGEQYAVGLALLVEGKVVLGVMACPNLPLASAVCATDNSSQEDVGCLFFATTGSGTYVQSLKGNSLPQKVQVSSNENLDEAKFLESYHKPIPIHGTIAKKLGIKALPVRIDSQAKYAALSRGDAEIYLRFTLNGYRECIWDHAPGSIITTEAGGVVCDATGKSLDFSKGKYLAHKTGIIVTTKKLKPWILKAVRESIEEENLYF
What is the function of this protein?
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.  May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (PubMed:10205895) (By similarity).  Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation.  Is also able to hydrolyze inositol 1,4-bisphosphate (PubMed:10205895).
What are the official names of this protein?
SAL2 phosphatase, 3'(2'),5'-bisphosphate nucleotidase 2, 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase 2, DPNPase 2, Inositol polyphosphate 1-phosphatase 2, IPPase 2, Inositol-1,4-bisphosphate 1-phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: YHCC_ECO57
Sequence: MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQQAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRGHDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHIVKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWCENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE
What are the official names of this protein?
Uncharacterized protein YhcC.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily.
Protein: HUTI_LEGPH
Sequence: MFACDELLLNASTIDATGLQLSNQAIVIRKGRIEWCGSEDQLPAHFQESAKSRKDCHGQLITPGLIDCHTHLVYAGHRAAEFRLKLQGVSYADIAKSGGGILSTVQMTRDASEEELIEQSLPRLLALKNEGVTTVEIKSGYGLDLQNELKMLRVARQLGEMAGVRVKTTFLGAHAVGPEFKGNSQAYVDFLCNEMLPAAKNMDLADAVDVFCESIAFSIRQAEQIFQTAKDLNLPIKCHAEQLSNMGASSLAARYGALSCDHLEFLDENGALNMVKANAVAVLLPGAFYFLKEKQKPPVDLLRQVGVGMAIATDSNPGSSPTTSLLLMMSMASQFFSMSIPEVLSAVTYQASRALGMEKDIGSIEVGKIADLVLWSIKDSAALCYYFAYPLPHQTMVAGEWVS
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_ACIC1
Sequence: MALTAKVKDELARLPVTKTCCRKAEVAATLRFAGGLHLVGGRIVVEAELDTGAAARRLRTALAELYGQHAELAVIAPGGLHRGNRYVVRVSRDGETLAKQTGLLDGRGRPVRGLPSQIVSGGVCDAAAAWRGAFLAHGSLTEPGRGCTLEVSCPGPESALALVGAARRLGVQAKSREVRGVERVVVRDGDAIGVLLTRLGAHDSVLAWEEYRVRREVRATANRLANFDDANVRRSARAAVTAAAKVKRALEILGDSVPEHLAAAGTLRMVHPQVSLEELGALADPPLTKDAIAGRIRRLIAMADRRADELGIPGTEAALVGELP
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: DUSTY_TETNG
Sequence: MEGHGAQRSSPLARDLTRAFTSYNKHTVLLKKNLKETHAFFREMRQNYSNTCASSTLSSDSSSQETGQFSCISFPSHEEEFLRNTVGAAPYILVLGQDCAARYQLLNCLLGDRLLPLGPEAGQACHGGQGNVCKRRKLCFTHGRQTRLSLALPGQYELVHQLAANCGRWETVPREDLEILDECEDPAHRQAELEITLHHPLLQEAKVMVVPCPSVQPIEEALEDCTRSVIPIILYAVNRDSLSSEQVADLRKVKEILSFPVCYVRLPDASAASAELGQRCEKDKSKLQKQLLSRGLLGSLSGNCSCGAPAQTAAPGAKPQSVVGENFEKLHRILVPFTRQVLQNQQVEAASLLNGLHCRCLDLFINQAFDMQRDLQITPRRLEYTREKEGELFTSLMTIANRKQEEMKDMIVETLGSMKEQLLEDAANLEFTDIIVTTNGDPVTSKEIKSCIQQIQDLIVVRLNQAVANKLISSVDYLRESFVGTLERCLSSLEKSHIESSVHNITSNHLKQLLNAAYHVEVTFHSGSSVTRLFWEQIKQIIHRITFVNPPAITPEWKRKVAQDAIESLSAAKLARSICSQFRTRLYSSHEAFAASLRQLEERHTGRLERTEDLWLRVRKDHAPRLARLSLESRSLRDVVLHGKPKLGRELGRGQYGVVYLCDSWGGHNPCALKSVVPPDDKHWNDLALEFHYTRTLPKHERLVDLHGSVIDHTYAGGSSIAVLLIMERLHRDLYTGLKAGLSLQERLQIALDVVEGIRFLHSQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYLCAGSVKLPEAFEKCSSKDQLWNNVRKGARPERLPCFDEECWQLMEACWNGDPSQRPLLGIVEPSLESITVRMCNCGSEQKSSSLEDSC
What is the function of this protein?
May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation.  May induce both caspase-dependent apoptosis and caspase-independent cell death.  May play a role in the embryonic development.
What are the official names of this protein?
Dual serine/threonine and tyrosine protein kinase, Dusty protein kinase, Dusty PK, Receptor-interacting serine/threonine-protein kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Apical cell membrane. Basolateral cell membrane. Cell junction.
Protein: KC12_ENCCU
Sequence: MRGEIMDYTICREIGKGGFGKVYEVKKKADQKSYALKIETNAPKAGRNSIINEIQAYSELQGCEKIPRLVDHGSYEGLTFLVLPLLKYSLKDLLERHPRFFTKKSATIVGKKLLNAIEFIHGKGRLHRDIKPENVMFGHNNRIYLVDFGMSAPYLRGDGSHIPEVGGKSVSGTLWYMSINTHRGIEQSRRDDLESLFYLLILLYKSRLPWMEPGASVSKKQEARTKEIKENLSVYDLCDGIHGKEHLIKFFQHISSLEFAEKPNYRYLNSLLDKIFHSNKELQGYKRAPKKEDTGLIRTSLWHKFISILSPFEVKYDG
What is the function of this protein?
Involved in DNA repair.  May regulate the activity of protein(s) involved in double strand break repair caused by gamma rays (By similarity).
What are the official names of this protein?
Probable casein kinase I homolog ECU11_1980.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADA_RALSO
Sequence: METHIKTVEFERPNMLAEAQSGASCVAHAWAKVPPALSREERDALKARIKRLLKERNAVLVAHYYVDADLQDLAEETGGCVSDSLEMARFGRDHSAKTLVVAGVRFMGETAKILSPEKTVLMPDLDATCSLDLGCPPDTFAAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLKIVQHLHEQGQKILWAPDRHLGSYIQQQTGADMLLWQGSCLVHDEFKGVELDLLRAEHPHAKVLVHPESPPSVVAQADVVGSTSQLIAAAQSLPADAFIVATDNGILHKMRMAAPGKRFIEAPTAGNSATCKSCAHCPWMAMNALTNLAEVLETGRNEIHVDPQIGQQAVRCITRMLDFAAREKTTVRPQGDLAANTQLFQGVGPA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_LARHH
Sequence: MSEVSNVIDIRGIMKMLPHRYPFLLVDRVLEIEEGKRIKAIKNVTANEQFFVGHFEQYPVMPGVLIIEALAQAAGILAIKTHDGEVRQENALYFFVGIDNARFKRQVIPGDTLVFEVEMLRVSRGIGKFAAKAFVDGELACEADLMCARREI
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_SALPB
Sequence: MSQVILDLQLACENHAGLPDEAQFQRWLDGVIPQFQEEAEVTIRLVDEAESHDLNLTYRGKDKPTNVLSFPFEAPPGIEMPLLGDLIICRQVVEQEAQEQSKPLEAHWAHMVVHGSLHLLGYDHIDDDEAEEMESLETEIMLAMGYEDPYIAEKIAE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_PSEPU
Sequence: MNPVIKTFQFGQSTVTLETGRIARQATGAVLVTVDNDVTVLVTVVGAKQADPGKGFFPLSVHYQEKTYAAGKIPGGFFKREGRPSEKETLTSRLIDRPIRPLFPEGFMNEVQVVCTVVSTSKKTDPDIAAMIGTSAALAISGIPFEGPIGAARVAFHESTGYLLNPTYEQLAASSLDMVVAGTSDAVLMVESEAQELTEDQMLGAVLFAHDEFQAVIQAVKELAAEAGKPTWDWKPAVANTELFNAIRAEFGEAVSQGYTITVKADRYARLGELRDQAVAKFSGEEGQPSASEVKEIFGEIEYRTVRENIVNGKPRIDGRDNKTVRPLNIEVGVLPKTHGSALFTRGETQALVVATLGTARDAQLLDTLEGEKKDPFMLHYNFPPFSVGECGRMGGAGRREIGHGRLARRSVQAMLPAADVFPYTIRVVSEITESNGSSSMASVCGASLALMDAGVPMKAPVAGIAMGLVKEGDKFAVLTDILGDEDHLGDMDFKVAGTAKGVTALQMDIKINGITEEIMEIALGQALEARLNILGQMNQVIGQSRTELSANAPTMIAMKIDTDKIRDVIGKGGATIRAICEETKASIDIEDDGSIKIFGETKEAADAAKQRILGITAEAEIGKIYVGKVERIVDFGAFVNILPGKDGLVHISMLSDARVEKVTDILKEGQEVEVLVLDVDNRGRIKLSIKDVAAAKASGV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIE_SCHJA
Sequence: EDVSDDEMRTKKQKRNLPRVFFDIRIGNADRGRIVMELRSDIVPRTAENFRALCTGDRGFGYHNCCFHRVIPQFMCQGGDFVKGDGTGGKSIYGRKFDDENFQLRHEGFGVLSMANSGPNTNGSQFFICTTKCDWLDGKHVVFGRVVDGQNVVKKMESVGSKSGKVKEPVTISRCGELI
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase E, PPIase E, Cyclophilin E, Rotamase E.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABF1_KLULA
Sequence: MSLYEYKHPIINKDLAAPDPVSAQKRSFPTLEAWYDVINDYEFQSRCPIILKNSHKNKHFTFACHLKSCPFKILLSYQGANNSGSSEDGSPHGLSGDGGSSSSGSNHHNGHTNLAEDGRAEDEDDDEDDDAAVTAAIAAAVAAVADSQETIKGPFVVTKIEPYHNHPLESNLSLQRFVLSKIPKILQVDLKFDAILESLCNDDDNTVAKFRVAQYVEESGILDIIKQRYGLTEAEMDKKMLSNIARRVTTYKARFVLKRKKDGVYAMPTAHQLTGGDHHQVQHHHHPSIPAHHQHQLPEGQQRDVQHHHQQQQQQLQHQEQHQSHVDSGHNVYQNRIGSISDNDDSAIHNLDDTNVRVAAAAAAAAAALQSRENHDTEDLKRTLEQVQDDESLDVGVPDSKRQLHRRERDRVAEALKMATRDILSNQSVDSDVNVDVDLVTGHKQLSPHDDMAEQLRLLSSHLKEVEAEENVSDNNLKKDDIPDENIQPELRGQ
What is the function of this protein?
General regulatory factor (GRF) that contributes to transcriptional activation of a large number of genes, as well as to DNA replication, silencing and telomere structure.  Involved in the transcription activation of a subset of ribosomal protein genes.  Binds the ARS-elements found in many promoters.  Binds to the sequence 5'-TCN(7)ACG-3'.
What are the official names of this protein?
ARS-binding factor 1, Bidirectionally acting factor.
What is the protein family that this protein belongs to?
Belongs to the ABF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIHC_SHIDS
Sequence: MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEKTTRNALQLLHFWNAEIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRKPLGIPAFLAIRDALMCAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTPNAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALFSHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCRGKPANVQVALDLNVKGFQQWVPEVLALAS
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: CYSD_SULNB
Sequence: MINRERLTHLKQLEAESIHILREVVAEFANPVMMYSVGKDSSVMLHLAMKAFAPSKLPFPLLHVDTKWKFKEMIEFRDQRAKDLGFDLVVYSNPEGEKMNISPFEHGSKVHTDVMKTQGLKQALNAGGYDAVIGGARRDEEKSRAKERIFSFRDKHHRWDPKNQRPELWNIYNTAIQKGESVRVFPISNWTELDVWQYIYLEGIPIPSLYFAKEREVVEYEGTKIMVDDDRMPETLRSTAQKEMVRFRTLGCYPLTGAINSSATTLPEIIKEMLLSTSSEREGRLIDKDQEGAMELKKIEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: NANH_PAESO
Sequence: MKKFIKILKVLSMAIVLSACNINGIFASNLNTTNEPQKTTVFNKNDNTWNAQYFRIPSLQTLADGTMLAFSDIRYNGAEDHAYIDIGAAKSTDNGQTWDYKTVMENDRIDSTFSRVMDSTTVVTDTGRIILIAGSWNKNGNWASSTTSLRSDWSVQMVYSDDNGETWSDKVDLTTNKARIKNQPSNTIGWLAGVGSGIVMSDGTIVMPIQIALRENNANNYYSSVIYSKDNGETWTMGNKVPDPKTSENMVIELDGALIMSSRNDGKNYRASYISYDMGSTWEVYDPLHNKISTGNGSGCQGSFIKVTAKDGHRLGFISAPKNTKGGYVRDNITVYMIDFDDLSKGIRELCSPYPEDGNSSGGGYSCLSFNDGKLSILYEANGNIEYKDLTDYYLSIENNKKLK
What is the function of this protein?
Sialidases have been suggested to be pathogenic factors in microbial infections.
What are the official names of this protein?
Sialidase, Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RHG28_HUMAN
Sequence: MEVEDSGGVVLTAYHSYARAQPPNAESRCAPRAAASHPLSRKSIPRCRRINRMLSNESLHPPAFSRSNSEASVDSASMEDFWREIESIKDSSMGGQEEPPPAEVTPVDEGELEAEWLQDVGLSTLISGDEEEDGKALLSTLTRTQAAAVQKRYHTYTQTMRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQNQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIKPQQSS
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 28, Rho-type GTPase-activating protein 28.
Protein: RL11_BORBU
Sequence: MAKKKAISWIKLQVPAAQAAPGAKIGQALGPHGVSGPQFVKEFNERTAKMDPGIVVPVIITVYSDKSFSFIVKTPPASILIKKAIGIESGSKKSNTDKVGTISKEKLMEIARIKMSDLNAKSESAAFKIIAGSARSMGVEVEK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RECO_YERPB
Sequence: MDGWQRAFVLHGRPYSETSLMLDLFTEGEGRMRVLAKGARGRRSNLKGCLQPFTPLLVRWSGRGEVKTLRSAEPVSLALPLSGSMLYSGLYVNELLSRVLEHQTSYSALFFDYLHCLQALAGSDGSPEHALRQFELAMLANLGYGVDFLHCAGSGQPVSDTMTYRYREEKGFIASLVVDHYSFTGRQLLALANREFPDADTLRAAKRFTRIALKPYLGGKPLKSRELFRQFVIKPPADPSP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RS16_LEGPL
Sequence: MVVIRLSRAGAKKRPFYHMVVTDSRKRRDGNYIERIGYFNPVARGQEVKLHIDMDKMTHWQKVGAQLSDRVSALLKEHSKKSETAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: IGL1_HUMAN
Sequence: QSALTQPPSASGSLGQSVTISCTGTSSDVGGYNYVSWYQQHAGKAPKVIIYEVNKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYEGSDNFVFGTGTKVTVLGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
What is the function of this protein?
Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin lambda-1 light chain, Immunoglobulin lambda-1 light chain MCG.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: KTHY_CHLPM
Sequence: MLITFEGIDGAGKSTQIRKLAAHLRSQGQEVLTLREPGGTEVAENIRLILLESRHDITPVGELLLFSASRAELVNEVIRPALKEGTTVILDRFFDSTTAYQGYGRGIDLPTLNSIIALSTGGLKPDITFYLDILPEEALIRKFSEKSIPLAFDNDELDRMERSGLDFYRKVYEGYRCIMQEEPDRFVSINARKSIQEIHTTVTKTLKEQRAGRQS
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: HSLU_HYPNA
Sequence: MKHLTPREIVAELDRHIVGQNAAKRAVAIALRNRWRRKQAPENLRGEITPKNILMIGPTGVGKTEVSRRLARLANAPFLKVEATKFTEVGYVGRDVEQIVRDLVEAAVGMIREQKRAGVDKAARDKAEERLLDALVGAEAQSSTREVFRRKLRAGELDDKEVDLDFADTNNPMQMLDLPGQGGSMSMINLGDMLGKAMGGRTRRVRTTVREAAKPLVTEEADKLVDEEQIVREAIMAVEEDGIVFLDEIDKIAARKDRGGADVSREGVQRDLLPLIEGTTVSTKRGAVKTDHILFIASGAFHVAKPSDLLPELQGRLPIRVELEPLTRDDLRRILVEPQASLIRQYEALMAAENVTLTFEDGAIDRIADMAEAVNKSIENIGARRLQTILERLLDDISFDAPDKGGETFTITASYVDEKVGSLAGNADLSKFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_XANC5
Sequence: MLPLVALVGRPNVGKSTIFNALTRTRDALVHDQPGVTRDRNYGVCRLDEQQPFIVVDTGGIAGDEEGLAGATARQARAAAGEADLVLFVVDGREGASSLDDEILAWLRKLARPTVLVINKIDGTDEETVRSEFARYGFSDVVALSAAHRQGIDELLDEVGARLPEEGAGELLDNDPARVRIAFVGRPNVGKSTLVNRLLGEERMIASEVPGTTRDSIAVDLERDGRQYRLIDTAGLRRRGKVEEAVEKFSAFKTLQAIEQCQVAVLMLDATEGVTDQDATILGAILDAGRALVVAINKWDGQSDYQRAQAEDLLSRKLGFVNWAEAVRISALHGSGMRELFQAIHRAHASATHEFSTSEVNQALEIAYETNPPPSIRGHVSKLRYVHPGGANPPTFIVHGTRLKVLPESYKRYLENFFRKRFKLVGTPVRFIFREGVNPYEGKKNPLSDRQVARKRRLMRHVKGK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.