PharMolix/UniProtQA huggingface dataset:
Protein: HEM3_PARPJ
Sequence: MNTETFSTPPHTLVIASRESRLAMWQAEHVRCALHKLYPSCDVKILGMTTRGDQILDRTLSKVGGKGLFVKELEAALADGRADLAVHSLKDVPMELPAGFALSTIMEREDPRDALVSNDYDSLAALPAGAVVGTSSLRREAMLRMRYPHLEVRPLRGNLDTRLSKLDRGDYAAIILAAAGLKRLGLGERIRALLDPEDSLPAAGQGALGIEIRADRADLAAWLAPLHHDHTAAAVEAERMVSRALGGSCEVPLAAYATWRDGALHLRGIVATPDGQRVLSAQASAPAPSVERAVALGQEVASALEQQGAMDIVRALSAASGPAAAKQGAAEDGAADSAATGE
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PA2AF_TRIST
Sequence: MRALWIMAVLLLGVEGHLMQFENMIKKVTGRSGIWWYGSYGCYCGKGGQGLPQDASDRCCFVHDCCYGKVNGCDPKDDFYVYSSENRDIVCGEDNPCTKEICECDKAAAICFRDNMDTYQNKYWFYPSSNCNEESEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows a moderate inhibition of ADP-induced human platelet aggregation when tested on platelet rich plasma.  Exhibits high hydrolytic activities and prefers the anionic micelles (dPPC with deoxycholate) to the zwitterionic micelles (dPPC with Triton X-100).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 Ts-A6, svPLA2, CTs-A6, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BGAL_SHIDS
Sequence: MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTNRPSQQLRSLNGEWQFVWFPAPEAVPESWLECDLPVADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGYYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQIRDFHVATRFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFGGEIIHERGGYADRVTLGLNVENPKLWSAEIPNIYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTSATDIICPMYARVDEDQLFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGRTIEVTSEYLFRQSDNELLHWTVALDGKPLASSEVPMNVAPQGKQVIELPELPRLESTGQLWLTVHVVQPNATAWSEAGHISAWQQWRLAANLSVTLPSAPHAIPQLTTSETDFCIELDNKRWQFNRQSGFLSQMWIGDEKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHTWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: ILVC_AZOSB
Sequence: MKVYYDKDADLSLIKGKKVTIVGYGSQGHAHAQNLNDSGVKVTVAVRKGGASWDKAKAAGLKVEEIAKAVKTADLVMILLPDENIPQVYKEEVEPNIKKGATLAFAHGFNVHYNQVVPREDLDVIMVAPKGPGHTVRSEYLRGGGVPSLIAVYQDKSGKAKDIALSYAAANGGTKGGVIETNFKEETETDLFGEQAVLCGGAVELVKMGFETLTEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVINAQSREAMRNALKRIQTGEYAKMFIQEGKTNYPSMTARRRLNAEHPIEQVGGQLRDMMPWIKAKALVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RM20_BOVIN
Sequence: MVFLSAPLWLRNRITDRYWRVQEVLKHARHFRGRKNRCYRLAVRAVTRAFVRCTRARSLKKRHLRTLWINRITAASQEHGLKYPAFILNLIKCQVELNRKVLADLAIYEPKTFKSLAALSKRRREEGFVAALGDGKEPEGIFSRVAQHH
What are the official names of this protein?
39S ribosomal protein L20, mitochondrial, L20mt, MRP-L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RS14A_YEAST
Sequence: MSNVVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  uS11 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (PubMed:15590835).
What are the official names of this protein?
40S ribosomal protein S14-A, RP59A, Small ribosomal subunit protein uS11-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: UNG_MYCSS
Sequence: MTARALSELVDQGWAQALEPVREQVAQMGEFLRAELAAGHRYLPAGANVLRAFSFPFDQVRVLIVGQDPYPTPGHAVGLSFSVDPEVRPLPRSLANIFTEYTADLGYPQPSNGDLSPWAQRGVLLLNRVLTVRPGTPASHRGKGWEAVTECAIRALVARDTPMVAVLWGRDAATLKPMLTGSACVAIESPHPSPLSASRGFFGSRPFSRANELLTQMGAEPIDWRLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBT56_ARATH
Sequence: MKKLTSLFPLLFLIPLLASCAEEKQVYIVYFGEHKGDKAFHEIEEHHHSYLQSVKESEEDARASLLYSYKHSINGFAAELTPDQASKLEKLAEVVSVFKSHPRKYEAHTTRSWEFVGLEEEETDSDVPRRKNDADDRFRVGRNFLKKAKHGDGIIVGVLDSGVWPESKSFNDKGMGPVPKSWKGICQTGVAFNSSHCNRKIIGARYYVKGYERYYGAFNATANKDFLSPRDPDGHGSHTASTAVGRRVLGASALGGFAKGSASGGAPLARLAIYKACWAKPNAEKVEGNICLEEDMLAAIDDAIADGVHVISISIGTTEPFPFTQDGIAMGALHAVKRNIVVAASAGNSGPKPGTLSNLAPWIITVGASTLDRAFVGGLVLGNGYTIKTDSITAFKMDKFAPLVYASNVVVPGIALNETSQCLPNSLKPELVSGKVVLCLRGAGSRIGKGMEVKRAGGAGMILGNIAANGNEVPSDSHFVPTAGVTPTVVDKILEYIKTDKNPKAFIKPGKTVYKYQAAPSMTGFSSRGPNVVDPNILKPDITAPGLYILAAWSGADSPSKMSVDQRVAGYNIYSGTSMSCPHVAGAIALLKAIHPKWSSAAIRSALMTTAWMTNDKKKPIQDTTGLPANPFALGSGHFRPTKAADPGLVYDASYRAYLLYGCSVNITNIDPTFKCPSKIPPGYNHNYPSIAVPNLKKTVTVKRTVTNVGTGNSTSTYLFSVKPPSGISVKAIPNILSFNRIGQKQRFKIVIKPLKNQVMNATEKGQYQFGWFSWTDKVHVVRSPIAVSLA
What are the official names of this protein?
Subtilisin-like protease SBT5.6, Subtilase subfamily 5 member 6, AtSBT5.6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAA_ZYMMO
Sequence: MSVSSIADKIVSESILIVDFGSQVTQLIARRVREAGVYSEIVPFNRAEEAFQRLQPKGIILSGSPASVVAEGSPRAPESFFQAGIPIFGICYGQQVMCHQLGGKVTANDVDGEFGRAFIDVIAPSPLFENLWKVGEKHQVWMSHADRVEALPEGFKPIAVSDGAPFALIADEKRRFYGMQFHPEVVHTPDGGKLIAHFVHDICGLAGDWTMAEFRQTKIAEIRKQVGDGRVICGLSGGVDSSVTAVLVHEAIGDQLTCVFVDHGLMRQGEAEQVVSLFREHYGIKLVHVNAEDRFLAGLKGVTDPETKRKFIGKTFIEIFEEEAKKIGGADFLAQGTLYPDVIESVSFLGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRDLGRELGMPDVFVDRHPFPGPGLAIRIPGEVTKERCDILRKADAVYLEEIRNAGLYNAIWQAFAVLLPVRTVGVMGDGRTYDSVCALRAVTSTDGMTAEIYPFQPEFLANVATRIVNEVRGINRVTYDFTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DPO4_FUSNN
Sequence: MERIIMHYDMDAFYASIEINRNPKLKNKPLVVGENIVTTASYEARKYDIHSAMKVSDAKLLCPKLIVLPVDKTEYIRISNEIHNLILKITNKVEFVATDEGYIDLTDVIKPENKKAFVIKFKQRIKELTNLTCSVGIGFNKLSAKIASDINKPFGFFIFENEEEFIKHISDKKIKIIPGVGKKFFEILKNDKIFYVKDIFKYPLDYLVKKYGKSRGENLYCSVRGIDFDEVEYQREIYSIGNEETFLIPLQNNSEIIREFNSLFEYTFERLLKNNVFTQSITIKMRYTSFKTYTKSKKLKFSTRSKDFLYNEMFELINSFEKEDEVRLLGVYFGDIKKSNLVQLALNKNL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURE_PYRAB
Sequence: MVKVGMPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLEG
What is the function of this protein?
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide mutase, N5-CAIR mutase, 5-(carboxyamino)imidazole ribonucleotide mutase.
What is the protein family that this protein belongs to?
Belongs to the AIR carboxylase family. Class I subfamily.
Protein: TRML4_HUMAN
Sequence: MAWGGVHTCCFHLCCCCSWPQGAVPEELHKHPGQTLLLQCQYSPKRGPYQPKSWCQQTSPSRCTLLVTSSKPWTAVQKSHYTIWDKPNAGFFNITMIQLTQNDSGFYWCGIYNASENIITVLRNISLVVSPAPTTSPMWTLPWLPTSTVLITSPEGTSGHPSINGSETRKSRAPACLGSGGPRFLVLVLCGLLLAKGLML
What is the function of this protein?
Positively regulates Toll-like receptor TLR7 signaling in macrophages.
What are the official names of this protein?
Trem-like transcript 4 protein, TLT-4, Triggering receptor expressed on myeloid cells-like protein 4.
What are the subcellular locations of this protein?
Secreted.
Protein: ADD_SALG2
Sequence: MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHRENITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLVQQRIGIESCLTSNIQTSTIASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDGEKRALREKVAAA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: DEOC_HALMA
Sequence: MDDIPDRIEHTVLGPTTTPADVRTCLDEALQYGMRACIPPWAVPLATEYANVPLTAVIDFPHGQGQTDSVCQAAKLAWDAGADELDMVCNVGLLKAGEDDAVRDHITEVVASVPVPVKVIVEAPLLSDAELERVGQLVADADAAYLKTATGFSEGGATVHDVEILSKYLPVKASGGVGSWADAKAMFEAGAERIGASSGDTIVREWQAETAGETVTEPESDRDGADTTDGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_DESVH
Sequence: MTNPSPKLTPMFEQYLRIKEDYPDALLFYRMGDFYELFFDDAETTARELQIALTCRNPNAELKAPMCGVPYHAVEGYISQLLDKGYRVAICEQIEDPKEAKGLVKRAVTRVLTPGTVIDDANLDAKEHNYLGALFWNQDAEAGAFAWVDVSTGEWSGLYSRKLAELWQWAQKMAPRELLLPEGVDTPAMATLGTTQTVRVPARSHFDLKSGTERVMRAQGVADLGSLGLEGKPELVRACAALLAYLAQTQKQELSHLAPFKPLNLGRHLIIDEVTERNLELFHRLDGRKGPGTLWHILDRTLTPMGGRLLEERMHHPWREASPIRETQQVVEWLFQDDVRREALRTALDLVYDLERLSTRIFLNRATPKDFIALRQSLSALPAVRATLERPANPEGTYPTDAETSGDTLPKPLSDMLSAWDDLADYADLLRRALTDNPPHLVTEGGLFRPGFDPDLDELLDLAEHGEARLQELLAEEQTVSGLPKLKLGYNRVFGYFFELSRAGADSVPEHFVRRQTLANAERFTTERLKELEEKLVSATDRRKTLEYRLFQSLRDTVAEARPRVLFMADMLAHLDFWQSLADVARRNGWVRPDVHTGHDIVIREGRHPVVEAMQGSASFVPNDLRMDEKRRLLLITGPNMAGKSTVLRQTAIICLLAQMGAFVPAREASIGIADRIFSRVGASDNLAQGQSTFMVEMMETARILRQASKRSLVILDEIGRGTSTFDGMALAWAVVEELTRRAGGGIRTLFATHYHEITSLEGRIPGVHNMNIAIREWNGDIVFLRRLVPGPADKSYGIEVARLAGVPHSVVQRARELLADLERTRDAARGTNSAPSRQTLPGLDLPSKQEQVDTIVAPPPCSGVEHPLLVALRDIDTDDMTPLEALKRITEWKQLWGTTREDRS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GATZ_ECOLX
Sequence: MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAAMEKSVELVKAYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCFAAESVATDCQREQLSYVIGTEVPVPGGEASAIQSVHITRVEDAANTLRTHQKAFIARGLAEALTRVIAIVVQPGVEFDHSNIIHYQPQEAQPLAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMFDEPQYWKKYYRTGFNDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGMEIPLGMISQYLPKQFERIQSGELSAIPHQLIMDKIYDVLRAYRYGCAE
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: LEUD_CLOB8
Sequence: MSVKGKVFKYGDNVDTDVIIPARYLNTSDANELAAHCMEDIDVDFVKNVKSGDIIVANKNFGCGSSREHAPLAIKTAGVSCVIASTFARIFYRNAINIGLPILECDEAVKNIDAGDELEVDFSTGLIKNLTKSQEYQGEAFPEFMQKIIDNDGLIGYIRNR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: DABA1_NITWN
Sequence: MVDALNLGRRLRVRSTAYVAGEPVPFFWPMRTFIHHNPLYGLEDMPFEQAVRRGAELFHARMFLPRSDYQRWQREGKVRPETLKEEIGRRSQDLPPVPGVDWPRWLHALMQTPHDRDAVVRGVRAKDVHAALHGHPPSAQAVDVAALLPELEQRLHARTLPEAVDALWGTGLADELDELVIKNCLDFFDEDQSAWRMPGRERGLFSAWSEVTRRNARMVLRRLHVRHILDHVQDAESAVVYVMEEMGIGAEAWPTYFTRVLTRLHGWTGFVRWRASAKHYYWAQQYPADIVDLLAIRLVMGLALLQESARHRGTPMRRDDLGAVVRERGAECVLRYALHSGEVLPDWAQRIDDTLSRGNGARCHDLLQRYWPLWQARLGQQQAAALRELAAAANATAALDALAPEDVEGLLQGLRDFAPQEGMVWTLAMEGQAIDKLLTQVQAPQDPPPDKIPFAQAWFCIDVRAEPIRRHLERVGNYQTFGIAGFFGVPVGFLGYGKGSESHYCPAVITPKNLVLELPAALDPHNEDFVSTLGHVLHDLKKSVLSPYVTVEAVGMLFGLDLFGKTLAPLGYSRWRRRIDTEKPVTRLLVDKLSREQADSIIRTLQRAMIVKALHTELKIERERVDDDMIRELREIALRRRDGPTRLRTTFGVPQTQEAEFIDKLRQVYGVDADYTNHQLERLGRIGYSLDEQVNYVHTALTMIGLTQTFSRFVLVVGHGGKTENNPYESALDCGACGGASGIVNARVFAQMANKPAVRERLAAMGITIPEDTWFMPALHVTTTDAIELFDLDLLPPRHLVYLERLRDGLRAASRLTAAERMPKLLPEAKALEPAEALRLANRLAVDWAQVRPEWGLSGNVYGIVGRRALTENSDLQGSAFLLSYDWRCDPRGRLLENLLAAPVVVGQWINLEHFFSTVDNAHLGSGSKVYHNVSGRFGVMTGSLSDLRTGLPMQTVMREGRPYHEPMRLIALIEAPLDFAGRVLERVVKVKSLVLGGWIRAIVIDPTQGYKPFVFNNGQWEERTPLIAPAEKEYSA
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA 1.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y757_CAUSK
Sequence: MSPTAGLGLKSQHYAEALASDAEGLWFEVHPENYMAAGGPRLRWLEAIREKRSLSLHGVGLSLAADADPDPDHLAALKTLADRFEPFGVSEHLAWSTHRGAHQPDLLPFPRTRAALDRVARNIERMQDVLGRTILVENPSLYLPLTGHDLDETDFLIELTRRTGCGLLVDVNNVFVSASNLGYAAETYLDALPAEAIGEIHLAGHGPDEGGSALLIDTHGAPIAESVWALYQRLIERVGPRPTLIERDDDIPAFDVLMAERDRAHGMLTPSAASRL
What are the official names of this protein?
UPF0276 protein Caul_0757.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: NCAP_I78A5
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRRDGKWMRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGARVVPRGQLSTRGVQIASNENMETMDSSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RL31B_STAS1
Sequence: MRQNIHPEYHNVIFLDTTTDFKFLSGSTKTSSETMEWEDGNEYPVIRLDISSDSHPFYTGRQKFAAADGRVERFNKKFGFKSSNE
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: OXLA2_BOTJR
Sequence: ADDRNPLEECFRETDYEEFLEIARNGLSDTDNPKEGWYANLGPMRLNEFSQENENAWYFIKDPGVLDYPVKPSEVGKHDDIFAYEKRFDEIVGGMDKEVTVTYQTSEKFEPPLPPK
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:28495622) (By similarity).  Shows very high enzymatic activity on L-Met and L-Leu, high activity on L-Ile, L-Phe and L-Tyr and moderate activity on L-His (PubMed:28495622, PubMed:30534149).  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, and antibacterial, as well as regulation of platelet aggregation (By similarity).  Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation (By similarity).  These different effects are probably due to different experimental conditions (By similarity).  In vitro, has a strong antiprotozoal effect against Leishmania amazonensis (IC(50)=4. 56 ug/mL) and Trypanosoma cruzi (IC(50)=4. 85 ug/mL) (PubMed:28495622).  It also causes cell death and DNA damage in hepatocarcinoma cells (HepG2) in vitro by inducing oxidative stress (PubMed:30654040).  It exerts cytotoxicity towards colorectal adenocarcinomahuman cells (Caco-2) by acting on multiple intracellular targets (PubMed:29222016).  It diminishes cell viability by decreasing mitochondrial activity, the activity of acid phosphatases, and lysosomal function (PubMed:29222016).  In addition, it increases intracellular levels of reactive oxygen species and DNA damage, it elevates the expression of the pro-inflammatory cytokine genes TNF and IL6, and lowers the expression of the apoptotic-related genes (PubMed:29222016).  Also induces cytotoxicity (IC(50)=1. 80 ug/mL) and apoptosis in MCF-7 cells (a human breast adeno-carcinoma cell line) by activating the intrinsic and extrinsic apoptosis pathways, but are not cytotoxic towards MCF-10A cells (a non-tumorigenic human breast epithelial cell line) (PubMed:28495622).
What are the official names of this protein?
L-amino-acid oxidase BjussuLAAO-II, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GPDA_HAEIE
Sequence: MITSQTPITVLGAGSYGTALAITFSRNGSPTHLWGHNPVHIAQMQTERQNYRFLPDVIFPEDLHLESNLAQAMEYSQDILIVVPSHAFGEILIKIKPHLKAHHRLIWATKGLERNTGRLLQTVVEEQLGTQYPLAVLSGPTFAKELAQGLPSAITLAANNEQFAREFQSRIHCSKGFRVYINSDMTGVQLGGAIKNVIAIGAGISDGMGFGANARTALITRGIAEITRLGISLGANTNTFMGMSGLGDLVLTCTDNQSRNRRFGLMLGKGLDAQMAMENIGQVVEGFYNTKEAYLLAQRQGVEMPITEQIYQMLFCGKNAQDVAISLLGRACKGE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2507_HALMA
Sequence: MYYAVVLVILAVVAGIAGFRGIAGLSFRVAKFLIVIFLVLALVTFLL
What are the official names of this protein?
UPF0391 membrane protein rrnAC2507.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLNA1_MAIZE
Sequence: MASLTDLVNLDLSDCTDRIIAEYIWIGGTGIDLRSKARTVKGPITDPIQLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRKGNHILVMCDCYTPQGEPIPTNKRYSAAKVFSHPDVAAEVPWYGIEQEYTLLQKDVSWPLGWPVGGYPGPQGPYYCAAGADKAFGRDVVDAHYKACLYAGINISGINGEVMPGQWEFQVGPSVGISAGDEIWVARYILERITEMAGIVLSLDPKPIKGDWNGAGAHTNYSTKSMREAGGYEVIKAAIDKLGKRHKEHIAAYGEGNERRLTGRHETADINTFKWGVANRGASIRVGRDTEREGKGYFEDRRPASNMDPYVVTGMIAETTILWNGN
What is the function of this protein?
Plays a role in the flow of nitrogen into nitrogenous organic compounds.
What are the official names of this protein?
Glutamine synthetase root isozyme 1, GS122, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y002_OSHVF
Sequence: MHIGRREMPRHRKARHCQRFVADSCRSTETHSQVEDRVVRALMEDDVDLWRKMKYMVISSKNNDDKTMDTMRKFCERVTMAEESVEDLYYEKKYVKRFDKDTDDYMGQVTLPSARELAAAMKVGGRIGERRRKRDERVNELERKELELCGYDLVDGQCVLTGNLTRE
What are the official names of this protein?
Uncharacterized protein ORF2.