PharMolix/UniProtQA huggingface dataset:
Protein: PRR12_MOUSE
Sequence: MDRNYPSAGFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAATAAEPSSPQLYNFSGAAPGPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHSLQHYLSCGGSYPSMGHRASLACSPLGGGEPSPGAGEPSKGGPSGATAGAAGRATGPETAGGGAAGGGGGYRPIIQSPGYKTSKGGYGPATGGATRPPPPRSTATPKCQSLGGPAAAYAAGKASGAGGAGSQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKGPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQSEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGASSYAAGAGGYKGKGDGSELLAGPGGSAAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGPADAAKGLGGSGGAGGAPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRMKDKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPSAQATQPAPHGLLLEAGGPDLPMVLPPPPPQLLPSVLSHAPSPSPSAPKVGVHLLEPATRDGAPQPPPPPPPPMPLQLEAHLRGHGLEPTAPSPRLRPEESLEPPGAMQELLGALEPLPSGPGDPGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGQTEDDGDPKTGAGPPPGPTAYDPYGPYCGGRASGTGPETPGLGLDHNKPPELPSTVNAEPLGLIQSGPHQSAPPPPPPPPPPPPVSEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEGPAMAGPASITTDGAKKPRGRGRGRGRKAEEMGGTRLEPLKPLKIKLSVPKAGEGLGAPSNDVISGVDHNSLDSNLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPASVPTRGLQPPPPTVPTVPHPAPSGPFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLTGPKDTSTPEEPPLDTGPTASGPPPLPSLPSSNSSGTPEPPLLEEKPPPTPPPAPTPQPAPPPPPPPPPVPALPSPTPLVTPVASSPPPPPPPPPPPPALPSPPPPPPPAPTTVPPVAPPEEPPAPSPEDPEPPDARPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPLPVRRSGQTKGPTPVGGNSAPPSKVQAPPPKPETPEKMTSEKPPEPAPEPAVPEPPAPEKPSPPRPVEKEKEKEKEKEKEKERVTRPLRSERATSGRQMRTDRSLATGQSTTSRLPKARPSKVKAEPPPKKRKKWLKEAVGNASAGDGPGGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVEMLVSTALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHTFPQLQVEQTGEGSPEEGAVRLRPAGEPYNRKTLSKLKRSVVRAQEFKVELEKSGYYTLYHSLHHYKYHTFLRCRDQTLAIEGGAEDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQAHSRCG
What are the official names of this protein?
Proline-rich protein 12.
What are the subcellular locations of this protein?
Nucleus. Postsynaptic density. Synapse, synaptosome. Note=A smaller form of approximately 150 kDa has been found in perisynapse, synaptosomes and postsynaptic density in 15 dpc, P1 and adult brains.
Protein: PLPR2_BOVIN
Sequence: MAGGRPQLKRSFSIIPCFVFVEILLGELARAFFPAPPSAVPIIGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVNDQGACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPPSGRRLSPWEDLSQAPTMDSPLEKLSVAQEPEGCRSHSTPARLTPSKPQNCARRGHLIPNCVSSRAPAMCSSPRVPRPRLRSEPTPLPLPLPLPAPAPSQGPSPSSPGPGGPGGGGSRGRKLLLPTPLLRDLYTLSGLYPSPFHRDNFSPYLFASRDHLL
What are the official names of this protein?
Phospholipid phosphatase-related protein type 2, Inactive phospholipid phosphatase PLPPR2, Lipid phosphate phosphatase-related protein type 2, Plasticity-related gene 4 protein, PRG-4.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EM1_WHEAT
Sequence: MASGQQERSQLDRKAREGETVVPGGTGGKSLEAQENLAEGRSRGGQTRREQMGEEGYSQMGRKGGLSTNDESGGDRAAREGIDIDESKFKTKS
What is the function of this protein?
It is thought to provide protection for the cytoplasm during the desiccation stage of embryo development.
What are the official names of this protein?
Em protein.
What is the protein family that this protein belongs to?
Belongs to the small hydrophilic plant seed protein family.
Protein: HSLU_BORBR
Sequence: MSANHMTPGEIVSELDKFIIGQNRAKRAVAVALRNRWRRQQVAEPLRHEIHPKNILMIGPTGVGKTEIARRLAKLANAPFIKIEATKFTEVGYVGRDVDTIIRDLTEYSIKQTRELEMRRVRSHAEDAAEDRILDALVPPPRGASGEPERGEDNSARQTFRKRLREGKIDDLEIEIEIAQPMPQMDVMTPPGMEEMAEQLRGMFAGLARDKKKSKKIKVREAFKLIVEEEAAKRVNEDDLRAAAITNVEQNGIVFLDEIDKIAARQETGGADVSRQGVQRDLLPLVEGTTVNTRYGMVRTDHILFIASGAFHLARPSDLIPELQGRFPIRVELDSLSAEDFVNILSETDASLIKQYTALLGTEDVKLEFTDDGIRRLAELAFSVNERTENIGARRLYTVMEKLLEELSFDASANSGEVITIDAAYVDLQLAETAGSQDLARYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_MAGMM
Sequence: MKIHLNGEPHNAEAGTTLEGLLMGLGFAPEKVAVERNKAVVSRGTYGAVVLQEDDQIEVVHFIGGGQHPPADSWSVAGLTFNSRLLVGTGKYKDFEETKIAIEASGAEIVTVAVRRVNVSNPNAPMLTDYIDPKKYTYLPNTAGCFTAEDAVRTLRLAREAGGWDLVKLEVLSDEKYLWPNNPETLKAAEILVQEGFKVMVYTTDDPHMCKRFEDLGCVAVMPLAAPIGSGLGVRNPYTTRIIVEQAKVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGAKDPILMAHAMKHAVLAGRQAYLAGRIQKKLYATASSPLDGTFF
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_OLEA2
Sequence: MHERTFHIMTFGCQMNVNDSDWLARALEARGFTQVPEHEAAIYIINTCSVRDKPEQKVYSLLGRIRRETKNRRNVTVCVGGCVAQQIGKGFFKRFSQVRLVFGTDGAASAPQAIERLVQEPHARISLLDFSEEFPERDAGWENGEVPVSAYVNIMQGCNNFCAYCIVPYTRGRQKSRSSAAVLDECRTLVGNGAREITLLGQNVNSYGLDPHGDGTTFARLLHDVAAIPGLERLRFMTPHPKDIAGEVIEAFGALKNLCPRVHLPLQSGSDRVLKAMGRKYDMARYMDIVTRLKAVRPDIQITSDLIVGFPGETEADFEQTLEAMRTVPFVQSFSFIYSDRPGTRAEMLPGKLSREEKTARLVRLQEVQNEYSEAALQAMVGKTVMVLFESPSPKSAAGSGTDAQNAAEESGRTASSWQGRDEHGFILNVHLPAPADLYGKIMPVTVTAARKHSLTGEPAGESC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y107_CHLMU
Sequence: MKKFVYKYSFGALLLLSGLSSCCPSSYGSTPAKNTAEIKEESVILREEPESGCKKKSSCCLRKFFSRKKPKEKPEPVLPNFKSYADPMTDAERKDLSFVVSAAAEKSSIALAMAQGEIKGALSRIREIHPLVLLQALAEDPALIAGMKKMQGRDWVWNIFMTELSKAFSQAASLGAFSVADVAAFASTLGLDSGTVTSIVDGERWAELIDVVIQSPTI
What are the official names of this protein?
Uncharacterized lipoprotein TC_0107.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0875/CT_734/TC_0107 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ARR21_ARATH
Sequence: MASAQSFYNQSSVLKINVMVVDDDHVFLDIMSRMLQHSKYRVIAVDDPKKALSTLKIQRDNIDLIITDYYMPGMNGLQLKKQITQEFGNLPVLVMSSDTNKEEESLSCGAMGFIPKPIHPTDLTKIYQFALSNKRNGKSTLSTEQNHKDADVSVPQQITLVPEQADVLKTKRKNCSFKSDSRTVNSTNGSCVSTDGSRKNRKRKPNGGPSDDGESMSQPAKKKKIQWTDSLHDLFLQAIRHIGLDKAVPKKILAFMSVPYLTRENVASHLQKYRIFLRRVAEQGLYSMLSDRGIDSMFRQTHIKEPYFNYYTPSTSWYDTRLNNRSFYSKPVHGFGQSKLLSTTREPVCFNQMPYNYMNRSSTYEPHRIGSGSNLTLPIQSNLSFPNQPSQNEERRSFFEPPVMANKIAQTSQVLGFGQLGPSAISGHNFNNNMTSRYGSLIPSQPGPSHFSYGMQSFLNNENVTYNPQPPANATTQPNLDELPQLENLNLYNDFGNTSELPYNISNFQFDDNKHQQGEADPTKFELPAAKFSTELNHEDDGDWTFVNINQGQSNGETSNTIASPETNTPILNINHNQNQGQDVPEFNDWSFLDPQELVDDDFMNSLFNNDMN
What is the function of this protein?
Putative transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'.  Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Could directly activate some type-A response regulators in response to cytokinins (By similarity).
What are the official names of this protein?
Putative two-component response regulator ARR21.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_CHLSY
Sequence: MMNFLRRLLGDSNEKELRRLQPIVEEINRLGPEFAALSDAELRAKTDEFRQRLADGETLDDILPEAFATVREAAHRTIGLRHYDVQLIGGIVLHQGKIAEMKTGEGKTLVATLPLYLNALEGKGVHLVTVNDYLAKVGAGWMGPIYHFLGLTVGFIAHDQSALYDPDFIDPDANPEDQRLVHWRPCTRREAYLADITYGTNNEFGFDYLRDNMAYEKSQLVQRELHYAIVDEVDNILIDEARTPLIISGPAQKSSDLYRQMAQLVRQLRRSSVTAKQVKEEGLEPDGDFFVDERTKSIYLSEKGIEKLERLLRIPPGESLFDPEHYEKTHYIENALKAQFIYQRDRDYMVTPNGEVVIIDEFTGRAMPGRRWSDGLHQAVEAKEGVAIKNENVTLATITFQNYFRMYKKLAGMTGTAYTEREEFAKIYNLEVVVIPTHKPMIREDLPDQIYATEEAKFNAVLREVQEMHEIGRPVLIGTTSVETSERISAMLKRAGIPHNVLNAKHHEREAAIIAQAGRKGAVTVATNMAGRGTDILLGGNPDGLLEEFLRKEGLTIETATPEQKRAAWEKARAQTEAEGEEVRRLGGLHVIGTERHEARRIDNQLRGRAGRQGDPGSSRFFLSLEDELLRRFGPVDRIKGLMERFVDSDVPLQAGLLDRTIEGAQTRVEGYNFDVRKHTVEFDDVMNKQRQIIYADRKAILDEADMRERVLDLMAEEIQRQIDEHLIDGFEEEDLTNLLRAYRRINSTLPASVTAETLKGKTKEEIEQYLLDHLETTYAERERAVTPELMRTIERRVMLGAIDRQWVDYLTAMDELRQNILLQAYAQRDPLVEFKRESFRMFDELKQNIARDIVYNIIPATFQYEAYLRQIAEEQARRLATAQTVSSDGNGEVVRKPQRRSTPQIGRNELCPCGSGKKFKHCHLGREHELASLLNAQPSAPPASKALKSTPATQTAVAEEAAKIQAAINSGKLPPTQTTPRGRQAPSVPRGKKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: YOAS_BACSU
Sequence: MNRMSTIFLKIALVLIGIPILALCIFLVPKVANYSAELFPNIAYIKYLVFIYLYVTAIPFYFALYQAFKLLSYIDKNKAFSGLSVRALKNIKYCAVTISIFYAAGMPVFYLMAEIDDAPGIIVIGLVIIFASMVIAVFAAVLQKLLKEAIDIKSENDLTV
What are the official names of this protein?
Uncharacterized membrane protein YoaS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDK_ACIB3
Sequence: MAIERTLSIVKPDAVSKNHIGEIFARFEKAGLKIVATKMKHLSQADAEGFYAEHKERGFFGDLVAFMTSGPVVVSVLEGENAVLAHREILGATNPKEAAPGTIRADFAVSIDENAAHGSDSVASAEREIAYFFADNEICPRTR
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_RUTMC
Sequence: MQVILLEKIQKLGDLGDLANVKAGYARNFLIPRSKVKPATKTNLAKFKLIKAELQASEAKILKNAQVIESKMTGTVCTIQANAGEEGKLFGSINTSDIQISLAASGFEVEKRNINMPETIHHTGKYEISVDLHTDITVSIKVVIEGFQEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YL358_YEAST
Sequence: MRNGKILCCHCFYNKGDHEDDEGGRSIESLCAVNLAEGLNPRTNGPGKDSFSFSTSGSKPSSSLSFPVTSSMVSSTSSYSSFLFLLVVNHLFSGRLRCGSPEFIIRSFTITLGPLNHNISPFVFFHGNISSLPDLLVWLCRSVRCKTSTFLVIEIGKTNEEAASIIILPKLPLDACDVKSSIIVGIL
What are the official names of this protein?
Uncharacterized protein YLR358C.
Protein: ATPD_DESDA
Sequence: MIDTVVARRYANAIFALGKKDGDDALSSRGECLAALGEALAAAPGLDMTLKSPVIGVEEKKAVLDKLLGKLKADQTMRSFCFLLADKERLAFLREISAWYGKLLDEAKGIVRGELVTAVKLSADKKAKLKESLEKKTGTALELTFAVDKDILGGMVLKMGDRVLDASLRAQLGILRETFKRGE
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RBSA_PARXL
Sequence: MQQPTSAVPRLELRRASKSFGRVRALSDGDLALWPGEVHALLGENGAGKSTLVKILAGVHQPDTGELLVDGVARRFATPAEARDAGLAVIYQEPTLFFDLSIAENIFMGRQPVDRIGRIQYDAMRREVDGLLASLGVDLRADQLVRGLSIADQQVIEIAKALSLNANVLIMDEPTAALSLPEVERLFAIVRKLRERDVAILFITHRLDEVFALTQRVTIMRDGAKVFDGLTADLNTESIVAKMVGRDLETFYPKAERPPGEVRLAVRGLTRIGVFKDISFDVRAGEIVALAGLVGAGRSEVARAIFGIDPLDSGEIWIAGERLTAGRPAAAVRAGLALVPEDRRQQGLALELSIARNASMTVLGRLVKHGLISTRSETQLARQWGTRLHLKAGDPDAPVGTLSGGNQQKVVLGKWLATGPKVLIIDEPTRGIDVGAKAEVYGALAELVRDGMAVLMISSELPEVLGMADRVLVMHEGRISADIARADADEERIMGAALGQPVGHPVQPIPPLGHAV
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NU2C_SISMO
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDRPWFYFISSTSLVMSITALLFRWKEEPIISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALISITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVSFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVSMGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSTLRSNNSIEWSMTVCVIASTIPGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic, NAD(P)H dehydrogenase, subunit 2, NADH-plastoquinone oxidoreductase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL23_SOLM1
Sequence: MEYANILLKPVISEKATMVKDAANQVVFFVHPAANKIEIAKAVEKAFSVTVKGVRVVKHKSLARSRMGRVTGRIPGYKKAYVTLAQGDKIEFFEGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL3_GEOUR
Sequence: MNKGLIGKKLGMTQIFAEDGRRIPVTVVEAGPCVVIQKKTKEKDGYSAIQVGFNSQEAAKANSAVVGHCKTAGSGVFSFLRELRVDNADQYSVGDVLSAEIFAPGDLVDVTGTSIGKGFQGVMKRWGFKGGRASHGSRFHRAPGSIGCSATPSRVFKNKKMPGQLGNEKVTVQRLKIVRVDAADNLILLNGAIPGSTNGLVLIKDSVKAKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PE25_MYCTU
Sequence: MSFVITNPEALTVAATEVRRIRDRAIQSDAQVAPMTTAVRPPAADLVSEKAATFLVEYARKYRQTIAAAAVVLEEFAHALTTGADKYATAEADNIKTFS
What is the function of this protein?
The PE25/PPE41 dimer induces both a strong humoral and cellular immune response.  PE25 protein alone induces low response (PubMed:18974870).  The dimer induces necrosis, but not apoptosis, in mouse macrophage cells (PubMed:25379378).  It also induces activation and maturation of mouse dendritic cells and drives Th2-biased immune responses (PubMed:26318856).
What are the official names of this protein?
PE-PGRS family protein PE25.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: EFGM_ASPTN
Sequence: MRYPSLARLPRRALSGLARAPVRLQSQNFLSQRCASTAALRSASAVAPACQSALHRQFQQRRYASATASAVLEAAASSPDNLTQEAIIDNLDPVEAERLSRVRNIGIAAHIDSGKTTCTERVLFYTGRIKAIHEVRGGDKVGAKMDSMDLEREKGITIQSAATFCDWVKKDKEGKEHKYHINLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTMTVDRQMRRYNVPRISFINKMDRMGANPFKAIDQINTKLKIPAAAVQVPIGAEDEFEGVVDLLRMKAIYNVGPSGEELRETDEIPEKVKAVAEERRNMLIETLADVDDEIAELFLSETEPTEQQLRDAIRRATIGLKFTPVFMGSALANKSVQPMLDGVIDYLPNPSEVQNLALDKKRDEASVKLVPYNSLPLVGLAFKLEESNFGQLTYIRVYQGTLRKGANVFNARNDKKVKIPRIVRMHSNEMEEVSEIGAGEICAVFGVDCASGDTFTDGQLGYTMSSMFVPEPVISLSIKPKNNKDAAKFSKAMARFQREDPTFRVTFDAESEQTLISGMGELHLDIYIERMRREYNVDCETGPPQVAYRETIGNHVEFDHLLKKQSGGPGDYARVVGYMEPTEKLEENVFEEQIVGGSISEKFLFACEKGFHLACEKGPLIGHKVLGTKMLINDGATHMTDSSEMSFKNATQQAFRKAFMESNPSVLEPMMKTVVTAPAEFQGDVIALLNKRNATINDSDVGVDEVTVYADCSLNGMFGFSSHLRAATQGKGEYTMEFSHYEKATPQLQKELIAKYQKAQADRHKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GP165_BPPH2
Sequence: MNQKEFQAVLDWMLSPTIIQFHEYNYMLQKSLPFLRR
What are the official names of this protein?
Gene product 16.5, gp16.5, Protein p16.5.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus gp16.5 family.
Protein: YCUD_SCHPO
Sequence: MSILNVIRSHHDVEPQNVEEEPPLTGQTIVTEDKLETSAKDKKHESPSMSEDEEGSVENVDAWDLTKALMSIDPNHPAHPHKWPLWKKLFVATVYTFLEVYVIWSSTACINFFDIYQTNWHCSIQVSYLVQSLFIVGNAFGPMLLGPMSDIFGRKWVYVGSLILYIIFQIPQALAYNLPMMAINSAIAGAFGSSALANVASSMCDIFTPETVGFGISLFVWGANAGASIGSPIGEALYDHWRWFYWMNMIVGGFFVILCVLCPETLPVINIMNYSSTTGEKTVQVSTLAKAKSAVVRTKFVLSTAFKLLCTEPIIMALGLYNGFAYGLIFLYLDGLFPVFVDNYKMGYMGANLTYLNFLVGVTIVVMLQPIQNWLYRWDKRRHGGVARPEARFLISLLTVWFFPAGLFWFAFTSDGRISWVSPLIAGGVLGVGDPQLWLAMINYITDSYPSVAGSAIAAFTLPSFAIAAVLVHLGIIMFDNMTTTWAMATLAFISLSLVATIYVIYFFGHLIRKHSRLAVTQQALQEAHDAKVLPEV
What are the official names of this protein?
Uncharacterized transporter C965.13.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Membrane; Multi-pass membrane protein. Note=Barrier septum. Cell tip.
Protein: ACTL6_HYDVU
Sequence: MLVYVCLVVILIQLPFGAAGGAALGVIAKVSVDAALQQIDDVWKENTVRYWKCAVENRSTKTLYALGTTQESGSMSTIFADIPPQSTGVFVWEKSRGAATGAAGVVHYEYDNKILSIMASIPYDWNLYSAWANVHLSDHKKGFSDLYNGKNGARYPTRAGNWGNVDGTKFFLTDKSHAEFKVIFSG
What is the function of this protein?
Pore-forming protein that forms hydrophilic pores and causes cytolysis (PubMed:31513812).  Compared to equinatoxin-2 (AC P61914), it reveals lower cytolysis activity (5-12-fold difference, tested on erythrocytes), a larger pore size (probably 2-3 nm) and different affinity to membrane lipids (100-fold lower affinity to sphingomyelin) (By similarity).  Binds to sulfatides (PubMed:31513812).  Shows cytolytic activity on HeLa cells, with a different potency than its paralogs (from most potent to less potent: HALT-4>HALT-6~HALT-1>HALT-3>HALT-7>HALT-2) (PubMed:31513812).  Pore formation is a multi-step process that involves specific recognition of membrane lipid by a protein aromatic residues rich region, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers (By similarity).  In vitro, binds to the folate receptor alpha (FOLR1), a GPI-anchored membrane protein that plays a major role in the uptake of folate/folic acid into cells via endocytosis, suggesting a possible involvement of this receptor in the mechanism of HALT-1-induced cell lysis (By similarity).  In vivo, does not cause visible paralysis in larvae of the blowfly Sarcophaga faculata, the most common arthropod prey of Hydra (By similarity).
What are the official names of this protein?
Hydra actinoporin-like toxin 6, HALT-6, Alpha-pore-forming toxin, alpha-PFT, DELTA-hydritoxin-Hma1f, DELTA-HYTX-Hma1f.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. HALT subfamily.
Protein: NAGZ_YERP3
Sequence: MGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRLPAAQSFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKTTGKHFPGHGAVTADSHKETPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQELGFEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASSRWQQANKALTALSERWDAHKQTLGQ
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.