PharMolix/UniProtQA huggingface dataset:
Protein: MTNN_VIBPA
Sequence: MKVGIIGAMEQEVTILKEAMTNCQTVNKAGCTFFSGQINDVDVVLLQSGIGKVAAAVGTTILLDEYQPDVVINTGSAGGFDSSLNLGDVVISTEVRHHDADVTAFGYEIGQMAGQPAAFKADEKLMDLAEKALEQMANTHAVRGLICTGDAFVCTAERQAFIRENFPSVIAVEMEASAIAQTCHQFNTPFVVVRAISDVADKESPMSFEEFLPLAAKSSSEMVFKMLELVK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: TSPO_PIG
Sequence: MAPPWLPAVGFTLVPSLGGFLSSRNVLGKGLHWYAGLQKPSWHPPHWTLAPIWGTLYSAMGYGSYMIWKELGGFSEEAVVPLGLYAGQLALNWAWPPLFFGARQMGWALVDLVLTGGVAAATAVAWYQVSPLAARLLYPYLAWLAFAATLNYCVWRDNQGRRGGRRPSE
What is the function of this protein?
Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial.  It is apparently not required for steroid hormone biosynthesis.  Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme.  Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (By similarity).
What are the official names of this protein?
Translocator protein, Peripheral-type benzodiazepine receptor, PBR.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
Protein: TRPA_FRATO
Sequence: MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDHLADGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISKLGSGYTYLLSRVGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKIIQNNISNKQKMLNELTYFVKEMKAATLN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: UBIA_ECOLI
Sequence: MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate (PubMed:4552989).  Geranyldiphosphate (GPP), all-trans-farnesyldiphosphate (FPP) and all-trans-solanesyldiphosphate (SPP) are also accepted as side chain precursors (PubMed:8155731).
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase, PHB octaprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SEC11_PYRTT
Sequence: MLGIADMQPRQLAAQVLNFALVLSTAFMMWKGLSAASDSPSPIVVVLSGSMEPAFQRGDLLFLWNRGADTQVGEIVVYNVKGKDIPIVHRVVRRYGGGKTPLRLLTKGDNNLADDTELYAAGQSFLNRQEDVIGSVVGFIPFVGYVTILLSEHPWLKQVMLGMMGVMVVLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit sec11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: TOP6B_METBF
Sequence: MEFTIAEELAKNQKSISVAEFFEKNRQILGFDSAPRSLITTVKEAVDNALDACEEAGILPDILVQIERTGQDYVTVIIEDNGPGIIKEQIPKVFAKLLYGSRFHALKQSRGQQGIGISAAVLYAQMTAGKQTKILSKTGSGNPAHYYELMINTSTNEPDILKDEIRDWFRPHGTQIELEMKAAYVKGRRQSISEYLKATAIVNPHARITLIEPDGNEEVFERATDKMPKPAEEILPHPEGIELGTLMKMLHYTERQKLAPFLRYSFCKIGLLTAEEICKASGLDPEIDPHALGRHEARKLIEAFEKVKIMSPPTDCLSPIGEELIYRGLEKETNVDFIATSTRKPAVYSGNPFVVEVGLAYGGKLPKEEKISIMRFANRVPLLYQQGGCVTTHAVEDIKWKQYGLNQPGGGVPVGPAILLIHVASINVPFTSESKDAIADIPVIKDEIDLAIKDVARKLKHYLSKQSNLKKRREKEIIITKVLPKMAVKVANILEKDVPDINPVVAKIMGNLLVHRKVKRNEDGTADVVIKVKNFGTSAYAFKVHEMLPCTILGAKPEPKVVTLGNDYDYVWDISAAAGSSKVLSYRIESTTDKELGTFPDLVVEGLEEELVTGAKAFKGV
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: RRF_BRUA4
Sequence: MSDAFDINDLKRRMEGAINSLKHDLNGLRTGRASASLLEPIVIEAYGSTMPINQVANITVPESRMLSVSVWDKSMVGAVERAIRDSGLGLNPITDGTTLRIPLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDTLKKLEKDSLISQDDGRVLSEKVQKLTDETIAEMDKVVAVKEGEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CABC2_BACTN
Sequence: MLILSFLCPAFLNAQIVTDERMFSFEEPQLPACITGVQSQLGISGAHYKDGKHSLEWTFEPNGKLELRKDLKFEKKDPTGKDLYLSAFIVWIYNEQPQDAAIEFEFLKDGRKCASFPFGINFKGWRAAWVCYERDMQGTPEEGMNELRIVAPNAKGRLFIDHLITATKVDARQQTADLQVPFVNAGTTNHWLVLYKHSLLKPDIELTPVSDRQRQEMKLLEKRFRDMIYTKGKVTEKEAETIRKKYDLYQITYKDGQVSGVPIFMVRASEAYERMIPDWDKDMLTKMGIEMRAYFDLMKRIAVAYNNSEAGSPVREEMKRKFLAMYDHITDQGVAYGSCWGNIHHYGYSVRGLYPAYFLMKDVLREEGKLLEAERTLRWYAITNEVYPKPEGNGIDMDSFNTQTTGRIASILMMEDTPEKLQYLKSFSRWIDYGCRPAPGLAGSFKVDGGAFHHRNNYPAYAVGGLDGATNMIYLFSRTSLAVSELAHRTVKDVLLAMRFYCNKLNFPLSMSGRHPDGQGKLVPMHYAMMAIAGTPDGKGDFDKEMASAYLRLVSSDSSSAEQAPEYMPKVSNAQERKIAKRLVENGFRAESDPQGNLSLGYGCVSVQRRENWSAVARGHSRYLWAAEHYLGHNLYGRYLAHGSLQILTAPPGQTVTPATSGWQQEGFDWNRIPGVTSIHLPLDLLKANVLNVDTFSGMEEMLYSDEAFAGGLSQGKMNGNFGMKLHEHDKYNGTHRARKSYHFIDGMIVCLGSDIENTNTDYPTETTIFQLAVTDKAAHDYWKNNAGEGKVWMDHLGTGYYVPVPARFEKNFPQYSRMQDTGKETKGDWVSLIIDHGKAPKAGSYEYAILPGTDRKTMTAFAKKPAYSVLQQDRNAHILESPSDRITSYVLFETPQSLLPGGLLQRTDTSCLVMVRKESADKVLLTVAQPDLALYRGPSDEAFDKDGKRMERSIYSRPWIDNESGEIPVTVTLKGRWKVAETPFCKVVSEDKKQTVLRFLCKDGASYEVELEK
What is the function of this protein?
Broad-specificity glycosaminoglycan lyase, which acts in an exolytic fashion degrading chondroitin sulfates and dermatan sulfate to yield only disaccharide products.  Has a preference for chondroitin 4-sulfate over chondroitin 6-sulfate.  Has extremely low activity against hyaluronic acid.  Is not active against acharan sulfate, heparin or heparan sulfate.
What are the official names of this protein?
Chondroitin sulfate ABC exolyase, Chondroitin ABC exoeliminase, Chondroitin ABC lyase II, Chondroitin sulfate ABC lyase II, ChS ABC lyase II, Chondroitinase ABC II, cABC II, Exochondroitinase ABC.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 8 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DYTN_MOUSE
Sequence: MDPSKQGTLNRVENSVYRTAFKLRSVQTLCQLDLMDSFLIQQVLWRGRSGESTETSISVQQLFQELRELFQRTGMGNAAQVHPRAPELTLSLLMAMFDRTGSGILKRQPVAAALVALSGDSPLTKYRAFFQLYAEKNRRGDDSQARMTRRVLRALLTDLQQIPTVVGESYTLRPVESAIHSCFRGVLSSGIKEEKFLSWAQSEPLVLLWLPTCYRLSAAETVTHPVRCSVCRTFPIIGLRYHCLKCLDFDICELCFLSGLHKNSHEKSHTVMEECVQMSATENTKLLFRSLRNNLPQKRQRVGAVGRQWLLDQLASRDSASHGPARLCLQYKCPKAPGYASSRRAVETAATGVLCQRPSPALQGNHNRHGQTIVNIKNELWRTRDSLNTLLRERRLLRKQLHRYKQKLQGTYALQEEQNCRFETKIRELTTNQDNLWTKLQQMRRDLQAMLQPLHPSSSPQTTASKIFHSLPDDGIRRGGDSSHIKRVTRDGPEWELLPNSAKVDRKHKCQASSGKALPDSEPQEIILQSTRKQNHPQKMLSKVHSSPSAHQQDTLQIPPTEVKIPAQTLSAGKEMESCSEKRNNLEDEELQALLPRLLDAFDLDSPTGLQPLMDMELYGRAQQVCRAFSVLVDQITLPTWSEEESRLKGPLV
What are the official names of this protein?
Dystrotelin.
What are the subcellular locations of this protein?
Cell membrane.
Protein: HBB_SAGOE
Sequence: VHLTGEEKSAVTTLWGKVNVEEVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMNNPKVKAHGKKVLGAFSDGLAHLDNLKGTFAQLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RLMN_PROMA
Sequence: MESHKIQLLGLDLSQLERLALDHGESLYRGRQLHQWLYQKGVDNLDDITVLPKAWRNSLIQKGISVGGLVEVNRFIAGDRTIKLLLSTGDGEIIETVGIPSGNRLTICVSSQIGCPMGCQFCATGKDGLKRSLKVNEIVAQVFAVKKAFNRSPSNVVFMGMGEPLLNIEEVLSSICCLNKDLGIGQRRITVSTVGVKNTLPQLAELALQFLGSVQFTLALSLHAPNQKLRESLIPSAQNYPIKLLLEDCRHYLDLTGRRVSFEYILLGHLNDHIEHAEELADLVGGFQSHVNLIAYNPIDGESFQRPSNQRVNIFIKTLQKRGIVVSLRASRGLDKNAACGQLRSMNM
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSHC_SALRD
Sequence: MPSPTERAAHRTPPAALGAFPDLFVDYCTDFDAVADFYPGDWQSRPARRAAATAAAKRPADREVLADTLLDQNERWGLDERTRSHIETLRDPDSIAVVTGQQVGLFTGPLYTIYKTITTLQLIEEWADQTGRPVVPVFWVEGEDHDFEEIAAAHVLQHNEVVPLSYEPGVDDNPGAVGRLALTDGIQDVVDRLDEALPPSDFKPAVMEQVRAAYQPGTRLEDAFARLMRSLFEDDGLVFMNPDDARLKALTRPLFRRDIEDPRASVAPVNAAGRALRDRGYHAQVNAHPTNLFWLGDDGRWAIDLEDENAFRLRGTDRTFSRSDLLNRLDETPERFSPNVVLRPLMQDHLLPTAAYVAGPGEVSYFAQYGGVYDWAGLDMPLIHPRASVSLVEGKVQKVLDKYGLTVADFRDGLEPLFQDVVVDTMEVDVDALFSEALPQLHQTLNALKPEVEAVDRTLGASTEATRSAIMDEMEALKQKVVRAEKRQQDEVRAQLKKAHTNLRPDGTLQERTINVLYYLNKYSPALLDDLRHALRTDTSAHQVVGV
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: DPO3A_VIBCH
Sequence: MSDPKFIHLRIHSDFSMVDGLSKVPPLVKKVAAMGMPAMALTDFTNLCGLVKFYSTAHNCGVKPIIGADFTLQSEEFGDELTKLTLLAKNNVGYKNLTLLISKAYLRGHVQHQPVIDKAWLVEHAEGLIVLSGGKSGEVGRALLKGNQQQVERCIEFYQTHFADHFYLELIRTGRADEESYLHFALDVAEQYDLPVVATNEVVFITEESFEAHEIRVAIHDGYTLEDPRRPKNYSPKQYLRSEAEMCELFADIPEALANSVEIAKRCNVTVRLGEYFLPNFPTGGMAIEDFLVMKSREGLEERLEFLFPDPEVRAKRRPEYDERLQVELDVINQMGFPGYFLIVMEFIQWSKDNDIPVGPGRGSGAGSLVAYALKITDLDPLEYDLLFERFLNPERVSMPDFDVDFCMDKRDQVIDHVAEMYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPFGFVDRISKLVPPDPGMTLEKAFIAEPALQELYDADEEVKELIDKCRILEGCTRNAGKHAGGVVISPTAITDFAPIYCDAEGNFPVTQFDKNDVETAGLVKFDFLGLRTLTIIDWALGLVNPRLKKAGKPPVRIEAIPLDDARSFRNLQDAKTTAVFQLESRGMKELIKRLQPDCFEDIIALVALFRPGPLQSGMVDNFIDRKHGREAISYPDEKWQHESLKEILEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRAVFQEGAEKNGVDGELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKTHYPAEFMAAVMTADMDNTEKVVGLVDECKNMGLTVLPPDINSGLYRFNVDDNGAIVYGIGAIKGVGEGPIEAILEARNKGGYFKDLFDFCARIDLKKVNKRVIEKLILAGALDRLGPHRAAMMASVDDAVRAASQHHQAEAFGQADMFGVLTDAPEEVEQKYTQVPEWPEKVRLEGERETLGLYLTGHPVDEYLKELTKYTSCRLNEAAPTRRDQSLTVAGLVIAARVMTTKRGTRIGLMTLDDRSGRMEVMLYSEALDRYAEWLEKDKILVVSGQVSFDDFNGGLKMSAREVMDLGSAREKFARGLSISILQSQIDQQFFERFSHILEPHRAGTVPVNVYYQRPDARARLTLGTEWRVTPSDTLLDELKQLLGHDQVELEFN
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAN1_ARATH
Sequence: MALPNQQTVDYPSFKLVIVGDGGTGKTTFVKRHLTGEFEKKYEPTIGVEVHPLDFFTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDVTARLTYKNVPTWHRDLCRVCENIPIVLCGNKVDVKNRQVKAKQVTFHRKKNLQYYEISAKSNYNFEKPFLYLARKLAGDQNLHFVETPALAPPEVHIDIADQQKNEAELLQAAAQPLPDDDDDIFE
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran-1, Ras-related nuclear protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDSB_ECO24
Sequence: MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IQM4_ARATH
Sequence: MGLSLSLLLSAWKEVVTTQFFSFKNPVESFLETRSFSLKLKEGGLTSRTNSFKSENPQEKSPKTGMERSLSFNSWEIVTEVETEPMNKEDEEIVEPTKPARNSLNGRNCERIQITKPTITPPTPFVFFSPRPVTELDAAATTLQKVYKSYRTRRNLADCAVVVEELWWKTLDAAALNLSSVAFFEEEKHETAVSKWARARTRAAKVGKGLSKDEKAQKLALQHWLEAIDPRHRYGHNLHFYYDVWSASMSAQPFFYWLDIGDGKDVNLEHHPRSVLQKQCIKYLGPLEREAYEVIVEDGKLMNKQSMTLINSTEDSKSIFVLSTTRTLYVGQKKKGRFQHSSFLSGGATTAAGRLVAREGILEAIWPYSGHYLPTEDNFNEFISFLEENNVDMTNVKRCSVNEEYSSFNSSGYEEEATKEEEAEKKPAETIVTEEQEEEKERERPVFQLAKRLSCKWNSGVGPRIGCVRDYPMELQSQAFEQVSLSPRISPGSTRFPSPYGPIPSPRPSPRVRVSPRLAYMGIPSPRVQVNC
What is the function of this protein?
May be involved in biotic and abiotic stress responses.
What are the official names of this protein?
IQ domain-containing protein IQM4, IQ motif-containing protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL10_HELPS
Sequence: MQKQHQRQHKVELVANLKTQFADAKALLICDYKGLSVRKLEALRNKACAQGIKVQVIKNTLAHIAMKETGYSDLDLKETNVFLWGDDQIALSKLVFDFQKDHKDHFVLKAGLFDKESVSVAHVEAVSKLPNKEELMGMLLSVWTAPARYFVTGLDNLRKAKEEN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MLTF_MANSM
Sequence: MKGLLLRIIAAFALVLWAIDMVFPWQQMMRSEENRYNAIQQRGKLVVGTVNNPVSYFIGNEGQAGLEYELSRAFADYLGVELEMKAMDNGEQLFDALEDNEIDIAAANLLYQAKKAETFQLGPAYYSASWQLVYRKGESRPQSLSQIKDKLIIARGSELPLILQGYQTKYPNLKWQLENNQTQEELLLQVAQGKIKYTVANSIDVSAVQQVRPEIAVAFDVTDEASVHWYLPNNSYNELQAALLDFMNTALEGGLIARIEEKYFNHFSQFDYVDMRQYVQAINDILPKYAPLFDRYKGDLDWRLLAAIAYQESHWNENATSPTGVRGMMMLTKDTAERMKIADRTDAEQSIKAGSEYLHWLISQVPDSIPKEDRIWFALTGYNMGLGHMLDARRLTKNLGGDPDNWLDVKKNLPLLAEKRYYPNLKYGYARGYEAFQYVENIRRYMNSIINYYRVQENADNKDKPSETDENLPLPLTDNQEKQE
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: UNG_BACP2
Sequence: MKPFLNDSWWAVMKSEFEQPYYQELREWMKEEYRTQTVFPKPDDVYRALHLTSYEEVKVVILGQDPYHGPGQAHGLSFSVQPGVKHPPSLRNIFQELKDDLGCPVPNHGSLVSWAEQGVLLLNTVLTVRKGEANSHKGKGWERVTDRVIDALNERDQPVVFVLWGRHAQNKKERIDQNKHYIIESPHPSPFSARNGFFGSRPFSKVNAYLKQMGTEEINWCIQDIE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAT1_CHICK
Sequence: MASFSIRAARPEDCSDLLRLIKELAKYEDMEDQVVLTEKELLEDGFGEHPFYHCLVAEVPKEQWSSEGHSIVGFAMYYFTYDPWIGKLLYLEDFYVMAEYRGLGIGSEILKNLSQVAVKCRCSSMHFLVAEWNEPSIRFYKRRGASDLSTEEGWRLFKIDKEYLLKMATEE
What is the function of this protein?
Enzyme which catalyzes the acetylation of polyamines.  Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine.  This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines.  Also involved in the regulation of polyamine transport out of cells.
What are the official names of this protein?
Diamine acetyltransferase 1, Polyamine N-acetyltransferase 1, Putrescine acetyltransferase, Spermidine/spermine N(1)-acetyltransferase 1, SSAT, SSAT-1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PROM4
Sequence: MPTIQQLIRTERKRLTRKTKSPALRSCPERRGVCTRVYTSTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIIRGTLDTAGVKDRRQSRSKYGAKVPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: IF3_CLOPE
Sequence: MLSEVNKISKNFAINQEIREKEVRLISSTGEQLGVVSGRDAQRMADEAELDLVMISPNAKPPVCKIMDYGKFIYEQSKKEKEAKKKQKVISVKEIRVSPTIEKHDLEIKAKNAKKFLEAGDKVKITVRFRGREAEHSHVGVKILDSFLAQLEEVCSVEKPAKLEGRNMIMILAPKKA
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_ACAM1
Sequence: MTDVPVSRIRNFSIIAHIDHGKSTLADRLLQTTGTVADREMKEQFLDNMELERERGITIKLQAARMAYQASDKEDYVLNLIDTPGHVDFSYEVSRSLAACEGALLVVDASQGVEAQTLANVYLAIEHDLEIIPVLNKIDLPGAEPDRVKQEIEEIVGLDCSGAILASAKTGIGIAEILESIVHLVPPPEDTTQEPLRALIFDSYYDLYRGVVVYFRVMDGTVKKGDRVRLMASGKEYDVDELGVLSPTQVQVDELHAGEVGYFAAAIKAVEDARVGDTITLAKAQAAEPLPGYVEAKPMVFCGMFPTDADQFPDLRDALERLKLNDAALNYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYNLDLIITAPSVVYRITTLKGETLLIDNPSSLPDPQHREKIEEPFVQVDMITPEEYVGTLMELGQSRRGTFKDMKYLTPGRTTLVYELPLAEVVTDFFDQMKSRSRGYASMEYHLIGYRENPLVKLDILINADPVDSLAAIVHRDKAYYTGRALVSKLRELIPRHQFKIPIQAAIGAKVIASESIPALRKDVLAKCYGGDVSRKRKLLEKQKAGKKRMKSVGRVDVPQEAFMAVLRITDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYT_EXISA
Sequence: MYMIQLTFPDGAVKEFEAGVTAEDVAGSISPGLRKKAIAAKLDGELIDYRRPIEHDGKIELVMPDSEDGLDLMRHSSAHLMAQAIKRLYGEDNNIYLGIGPTIENGFYYDIEMDRRINEEDLPEIEKMMKRIVDENLEITREVVSRDEALARYKELGDPLKIELIEDIPADQTLTIYHQGEFFDLCRGPHVPSTSKLKIFKLMSVAGAYWRGDSDNKMLQRIYGTAWATKEQLAEHLRLLEEAKERDHRKLGKELDLFFVSQEVGQGLPMWLPKGASIRRTVERYIVDKELELGYQHVYTPVLGSVDLYKTSGHWDHYQDDMFPKMEMDNEELVLRPMNCPHHMTIYKHEPRSYRELPLRIAELGGMHRYEMSGALTGLQRVRYMVLNDGHTFVTPEQMKQEFKDIVHLIQEVYADFGIKDYRFRLSYRDPADKEKYFDNDAIWEMAQSQLKETMDELELPYFEAEGEAAFYGPKLDVQVRTALGKEETLSTVQLDFLLPERFDLTYTGPDGKDHRPIVLHRGVVSTMERFVAYLIEEYKGAFPTWLAPVQVKLIPVSHVHDEYVAEVKAELVKRGVRVETDLRDEKLGYKIREAQMKKIPMTLVLGDKERDERAVNIRRYGQQEQVSASLDEFIASLTDEIANRSR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTA_BUCAP
Sequence: MLNSCINKIKKKKNIKKIILMLIFIFSVNFFTKNTNQGKQYEDKLNKDFTNIKKINIKNKLVNQKEFLLQLEKIKIFSPNLYSKNISIYNAILKWLKKRAEINELNKFRIKLFQMKGVDQYGNVKITGYYTPIVKASKIKKNNFIYPIYRTPSNFKKNEKLPQRKDIYNGFLKKEYILAYSDSLINNFIMEIQGSGFIDYGDNKPLIFFGYAKKNNWPYTSIGQILIKNGDIQKKNISMNTIKNWCTHHTQKEIQNLLEKNKSFVFFQETKRKEVYGSSAVPLVEKAAIAVDKSVIKIGSVVLVKIPVLDKNGIFIHKYEMHLLIALDVGGVIKGQHFDVYQGIGEKAGKLAGFYNHYGYAWVLKI
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity).
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase A homolog, Murein hydrolase A.
What are the subcellular locations of this protein?
Note=In closely related bacteria this protein is attached to the outer membrane by a lipid anchor. This is apparently not the case here.