PharMolix/UniProtQA huggingface dataset:
Protein: SYT_ACIBY
Sequence: MPIITLPNGDQKSFDHPVSVMEVAQSIGPGLAKNTVAGRVNDRLVDACDLITEDSTLQIITPKDEEGLEIIRHSCAHLVGHAVKQLFPEAKMVIGPVIEEGFYYDIWMPRPFTLDDMAAIEERMKKLIDQDYDVIKKMTPRDEVIKVFTDRGEEYKLRLVEDMPEEKAMGLYYHQEYVDMCRGPHVPNTKFLKSFKLTKISGAYWRGDAKNEQLQRIYGTAWADKKQLAAYIKRIEEAEKRDHRKIGKALDLFHMQEEAPGMVFWHANGWTIYQVLEQYMRKVQQDNGYQEIKTPQIVDFTLWEKSGHAANYAENMFTTHSESRNYAVKPMNCPCHVQVFNQGLKSYRDLPIRLAEFGSCHRNEPSGSLHGIMRVRGFTQDDAHIFCTKEQIGKEVADFIKLTLDVYKDFGFEEVQMKLSTRPEKRVGDDALWDLAEKSLADALDAAGLEWELQPGEGAFYGPKIEFSLKDCLGRVWQCGTIQCDFNLPVRLDASYVTEENERDQPVMLHRAILGSFERFIGILIEHYAGFMPPWLSPVQACVMNITDSQAEASEQVVAKLKENGLRAISDLRNEKIGFKIRERTLERIPYLLVLGDREVEEGTVNVRTRSGKNLGTMSVDAFIDLVKSAVAERGRYIVE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOY_STAAT
Sequence: MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFNIEFITKLEGAHLDYEKENSEHFNVEIAK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: PLDA2_ORYSJ
Sequence: MAHLLLHGTLEATILEADHLSNPTRATGAAPGIFRKFVEGFEDSLGLGKGATRLYATIDLGRARVGRTRVVDDEPVNPRWYEVFHIYCAHFAADVVFSVKAAQPIGATLIGRAYLPVRELLSGEAIERRLDILDAGRRRISHGPTIHVRLQFRDVAGDRHGWGRGVSGARYPGVPYTFFSQRPGCRVTLYQDAHVPDAFAPRIPLAGGGYYRQGRCWEDVFDAISNAKHLIYLTGWSVYTEITLIRDGTRQRPGGDATLGELLKRKASEGVRVLLLVWDDRTSVESLGMKWGFMSTHDAETADYFRGTDVRCVLCPRNPDAGRSAIMGAQIAYMITHHQKTVIVDHDMPVPRGGGSRRIVSFVGGLDLCDGRYDTQFHSLFRTLDTAHHSDFHQPNLDGAAVTKGGPREPWHDIHSKIEGPAAWDVLYNFEQRWRKQGGDKDLLLDLKAMADLIIPPSPVMFPDDGEAWSVQLFRSIDGGACFGFPSTPEAAARSGLVSGKNNTIDRSIQDAYIHAIRRAKNFIYIENQYFLGSSFAWKADGIRPEDIEALHLIPREISLKIVNKIEAGERFAVYVVLPMWPEGPPASGSVQAILDWQRRTMEMMYYDIAVALEAKRINADPRDYLTFFCLGNREVKLNGEYEPAGRPLDGTDYAKAQKARRFMIYVHSKMMIVDDEYIIVGSANINQRSMDGGRDSEIAMGAFQPCHLNTKGLVARGQIHGFRMSLWYEHLGMLHDNFLNPESLECVQRVNKMADKYWDLYASDELNDDLPGHLLTYPVRVTKEGTVTELPGAKFFPDTQAPVIGTKGNLPPFLTT
What is the function of this protein?
Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond.  Plays an important role in various cellular processes.
What are the official names of this protein?
Phospholipase D alpha 2, PLD alpha 2, Choline phosphatase 2, Phosphatidylcholine-hydrolyzing phospholipase D 2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. C2-PLD subfamily.
Protein: NINF_BPP21
Sequence: MIDPNRSYEQESVERALTCANCGQKLHVLEVHVCEYCCAELMSDSNSSMHEEEDDG
What are the official names of this protein?
Protein ninF.
What is the protein family that this protein belongs to?
Belongs to the ninF family.
Protein: PUR2_METAR
Sequence: MKVLVIGSGGREHAIVEALARSEYHPKIYAVMGNANPGIRRRAEDYLLEKETNVPAIVQYAQDCNVDMAIIGPESPLAAGLADELELNGIPVVGPRKDAARIEFDKAWTREFMARNNIKGLPKFKVYDDYDDACRYLEDNPDVVVKPAGLTGGKGVKVMGEHMHTLEEAREYVKSVLEHDRVVIEERLKGEEVTIMAFVDGKHVAPMPTVQDHKRAYEDDQGPNTGGMGSYTDNIDLLPFMTLDDYNEGVAIMEQTVKAMEKDVGVPYKGVLYGQFMITRDGMKVVEFNARFGDPEAMNVLSLLKTDFVDICEAIVDGSLDKLKIEFERSATVCKYVVPAGYPDNPVKDAPLTVVEKPEYLVYYASVNERDGKVYTTSSRSLAIVGVADTIADAEILSEEGLSNVQGEFHCRHDIGKERLIRKRIEHMDAIRG
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: RECK_CHICK
Sequence: MAAAVAAWPWALFCLAAVPPLLSPGAAGLSCCYHAKDNLMCRDVCEQILSSKSDSRLKHLLQRAPEYCPESMGEVWGCINSSLPGVLKKSDGWVGLGCCELAIAVECRQACKQASSKNDILKVCRKEYENALFSCINRNEMGSICCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDYACQTACKRILMSMKTELEIVDGLIEGCKTMPLPQDPLWQCFLESSRSVHPGVTVHPPPSTGLDGAKLHCCSKANSSTCRELCTKLYSTSWGSSQSWQEFDRFCEYNAVEVSMLTCLADVREPCQLGCRNLSYCTNFNNRPTELFRSCNSQSDQGAMNDMKLWEKGSIKMPFINIPVLDINKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDHNKFPEGHTAESICELLSPTDDLENCIPLDTYLSPSSLGNIVEDVTHPCNPNPCAANQLCEVNRKGCQSGELCLPYLCVPGCKLGEASDFIVRQGTLIQVPSSAGDVGCYKICTCGHTGLLENCVEMHCVDLQKSCIVGGQKKSHGTSFNIDCNVCSCFAGNLICSTRQCLTEHSSEDERQKFTGLPCNCVDQFVPVCGQNGRTYPSACIARCVGLQDNQFEFGSCISKDPCNPNPCSKNQRCIPKKQVCLTSFGKFECSQHECVPRQLNCDQTQDPVCDTDSVEYSNVCTLYQKGKNLAYRGPCQPFCKSVEPVCGHNGETYSSVCAAYSDRVAVDYYGHCQAVGVLSDYGFHTECAFVKCPQLSATGCKPVIAPGACCPLCAGMLRILYDKDKLDNFARVTNKKPITVLDILEKLRLHVSVPQCDVFGYLSIESEIVILIIPVDQKPKPLQIEACNKEAEKIESLINSDSPTLASHVPLSALIASQVQVSFSISSPSVKVGPVLHCLFISFSFTLLKLMDYI
What is the function of this protein?
Functions together with ADGRA2 to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B) (By similarity).  Plays a key role in Wnt7-specific responses: required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity).  Acts as a Wnt7-specific coactivator of canonical Wnt signaling by decoding Wnt ligands: acts by interacting specifically with the disordered linker region of Wnt7, thereby conferring ligand selectivity for Wnt7.  ADGRA2 is then required to deliver RECK-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex.  Also acts as a serine protease inhibitor (By similarity).
What are the official names of this protein?
Reversion-inducing cysteine-rich protein with Kazal motifs.
What is the protein family that this protein belongs to?
Belongs to the RECK family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: RS7_CORDI
Sequence: MRKNAAPKRPIVKDPVYGSEVVTQLVNKVLLDGKKSTAERIVYGALDKCKEKTGIDPVLTLEKALGNIKPDLEVRSRRVGGATYQVPVEVRPARANTLALRWLVTFTRQRRENTMIERLANEILDAANGLGASVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: LPXK_SHIDS
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYCLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSIDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSTGQTLVMTEKDAVKCWAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: ATG7_CHICK
Sequence: MAAVSNESQNPVDPGSSKLQFAPFSSALNVGFWHELTQKKLNEYRLDETPKVIKGYYYNGDPSGFPARLTLEYSAFDINASIPARCCPAFGTLYNTNTFETFKSCDKKSLLEKEANEIWESIKSGAALENPMLLNRFLLLTFADLKKYHFYYWFCYPALCFPDGIHVIQKPVCLGDRFSLNQIQALQKAYDELCQTEGVTAFPYFLIKYHDNSVVVSPLKKWDGFFQDQGGKVTVGVYDPCNLSHYPGWPLRNFLILASHKWGNILQSIEVLCFRDRTMQGVRDITHSIIFEIKLPQGAFGPDCPKAVGWEKNQKGGMGPRVVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLEKIVSAKCLLLGAGTLGCSVARTLMGWGVRKITFVDNARISYSNPVRQPLYEFEDCLSGGKPKALAAAERLQKIFPGVNSEGYNMSIPMPGHPVNFSEVTMAQARKDVATLEELIDAHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQETGNACFSTAPGPSDLLGSSLFSNIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAMIAGALAVELMVSVLQHPEGGYAVASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETV
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.  Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine.  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.  Required for autophagic death induced by caspase-8 inhibition.  Facilitates LC3-I lipidation with phosphatidylethanolamine to form LC3-II which is found on autophagosomal membranes (By similarity).  Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress (By similarity).  Plays a role in regulating the liver clock and glucose metabolism by mediating the autophagic degradation of CRY1 (clock repressor) in a time-dependent manner (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7, APG7-like.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: ATPB_LACCB
Sequence: MPNSTGKIAQVIGPVVDVAFPINGDLPEINNALTVAKKDGSQLVLEVALELGDGVMRTIAMDSTDGLQRNMAVQDTGGPISVPVGKDTLGRVFNVLGDPIDGGEAFGPDHRRDSIHRDAPKFEDLNTSSEILETGIKVIDLLEPYLRGGKVGLFGGAGVGKTVLIQELIHNIAEEHGGISVFTGVGERTREGNDLYFEMKESGVLENTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATTFAHLDATTNLERRLTEQGIYPAVDPLESSSSALTPEIVGDEHYKVATEVQQVLQRYRELQDIISILGMDELSDEEKVVVARARRIQFFLSQNFNVAERFTGQPGSYVPVEETVKGFKAILDGKYDDYPEDAFRSVGRIEEVVEKAKKMGFAPDDQNTDADEKPAAQAAAN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1481_BREBN
Sequence: MGRKWNNIKEKKASKDASTSRIYARFGKEIYVAAKQGEPDPESNRALKVVLERAKTYSVPKAIIDRAIDKAKGGSDETFSDLRYEGFGPNGSMIIVDALTNNVNRTAPEVRAAFNKNGGNMGVSGSVAYMFDPTAVFGLEGKSSDEVLEILMEADVDVRDILEEDGAVIVYADAEQFHAVQEALKNGGVSEFTVAELTMLPQNEVTLTEDVQAQFEKLIDALEDLDDVQQVYHNVDLGE
What are the official names of this protein?
Probable transcriptional regulatory protein BBR47_14810.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_NOCFA
Sequence: MVEHTRKGRLVVLVGPSAVGKSTVVRCVRERLPELVFSVSATTRAPRPGEVDGRDYRFVTRAEFDAMIEAGELLEWAEIHGGLQRSGTPAAPVREALAAGKNVLLEVDLEGARSVRKVMPEARLVFLAPPSWDELVARLTARGTETPEVIARRLETARIELAACDEFDNVIVNDEVTSACEQLVSLFVSTNSR
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAB2_TULGE
Sequence: MSVALFCGPPPAVSFGCKDGRGRKGMVRSKDIVRQTVKPPAHACRLIGWNKYPGSVVPTNSSLSPSPTALDDEIELDLSPFLIIYKDGRIERLKGTTVIPACPEVATKDVIIDPATGVSVRLYLPNVVDLPSKKLPVLVYFHGGGFVIENTGSPNYHNYLTLLAAKSGLLIVSVNYRLAPEHPIPASFDDCMAGFNWVVSHSAGPAPEPWLARHGDLTQILISGDSAGGTVTHYVLLRADAGVIEGAALVHPYFLGSKRLENQTEEDFEFHEKLWRLSTPDTEGLDDPLINPLAPGAPSLAGLKCKRAVVFVAELDFLVERGRMYYDALVKSGWGGEAELVHQKGVGHVFHLSDYSGDVSVDMMAKMVAFLRGE
What is the function of this protein?
Lactone-forming carboxylesterases, specifically catalyzing intramolecular transesterification, but not hydrolysis.  Involved in the biosynthesis of tulipalins, defensive chemicals that show antimicrobial activities against a broad range of strains of bacteria and fungi.  Substrates are 6-tuliposide A > 6-tuliposide B.
What are the official names of this protein?
Tuliposide A-converting enzyme b2, amyloplastic, TgTCEA-b2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Plastid, amyloplast.
Protein: Y1213_VIBC1
Sequence: MLTINSDAKLKDLLEFPCSFTYKVMGHAKPELPELVLEVIQRHAPGDYSPTVKPSAKGNYHSVSINITATSIEQVETLYKELGEIDIVRMVL
What are the official names of this protein?
UPF0250 protein VIBHAR_01213.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: ATPA_FRAAA
Sequence: MTELSIRPEEIRDALREYVDSFQATSAGREEVGRVVVTGDGIARVEGLPHTMTNELLEFSGGVLGLALNLEIGEIGTVILGEAEHIEEGQEVRRTGEILAVPVGDGFLGRVVDPLGRPIDGLGEIQAEGTRALELQAPTVVQRQPVKEPLQTGIKAIDAMTAIGRGQRQLIIGDRQTGKTTVAIDTIINQRDNWASGDPSKQVKCVYVAIGQKKSTIREVVNTLEEAGALAYTTVVAAPADEPAGFKYIAPYAGSAIAQHWMYNGQHALIVFDDLSKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELGGGSLTGLPIIETKASDISAYIPTNVISITDGQIFLESDLFNQGVRPAINVGTSVSRVGGSAQTKAMKSVAGRLRLDLAQYRELEAFSAFGSDLDKASRDQLARGARLVELLKQPQNQPYPIERQVVSIWAGTTGKVDDVPVADVRRFESEFLDYVGRSHRGIYDAILGSGKLGDDVIQELNSAIAAFKNQFTLSDGKPLVNEAAASPLDPSAVRKESIPVHRAPARTDDEG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL18_HELPG
Sequence: MNAKALYKKKALRDRRKLRIKSKLLGDALRPRVSVFRSNRYFYAQAIDDVKQSTITHIDGRKMGFKNTQEDAKKLGALFAEELKKAGIERAVYDRNGYLYHGVVAAFAESLRENGIAL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RIMM_ECO81
Sequence: MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLEEGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLTTRSIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B3AT_CHICK
Sequence: MEGPGQDTEDALRRSLDPEGYEDTKGSRTSLGTMSNPLVSDVDLEAAGSRQPTAHRDTYEGYVELHELVLDSRKDPCWMEAGRWLHLEESMEPGGAWGSHLPLLTYHSLLELHRAFAKGVVLLDVAANSLAAVAHVLLDQLIYEGQLKPQHRDDVLRALLLRHKHPSEAESVWTLPAAQLQCSDGEQKDADERALLRDQRAVEMRELHGAGQSPSRAQLGPQLHQQLPEDTEATLVLVACAAFLEQPLLALVRLGAPCPDAVLAVPLPVRFVLTVLGPDSPRLSYHEIRRAAATVMADRVFRRDAYLCGGRAELLGGLQGFLEASIVLPPQEVPSEQHLHALIPLQRHAVRRRYQHPDTVRSPGGPTAPKDTGDKGQAPQDDDPLLRTRRPFGGLVRDIRRRYPKYLSDIRDALNPQCLAAVIFIYFAALSPAITFGGLLGEKTRGMMGVSELLLSTSVQCLLFSLLSAQPLLVVGFSGPLLVFEEAFFRFCEDHGLEYIVGRVWIGFWLILLVLLVVACEGTVLVRYLSRYTQEIFSFLISLIFIYETFAKLVTIFEAHPLQQSYDTDVSTEPSVPKPNTALLSLVLMAGTFFLALFLRQFKNSVFLPGKVRRLIGDFGVPISIFVMALADFFIKDTYTQKLKVPRGLEVTNGTARGWFIHPMGSATPFPIWMMFASPVPALLVFILIFLETQITTLIVSKPERKLVKGSGFHLDLLLIVAMGGLAALFGMPWLSATTVRTITHANALTVVGKSAVPGERAHIVEVKEQRLSGLLVAVLIGVSILMEPILKYIPLAVLFGIFLYMGVTSLFGIQLFDRILLLLMPPKYHPKEPYVTRVKTWRITSSPLTQILVVALLWGVKVSPASLRCPFVLVLTVPLRRLLLPRIFSEIELKCLDTDDAVVTFEEAEGQDVYNEVQMPS
What is the function of this protein?
Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein.  Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin.  Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane.  Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.
What are the official names of this protein?
Band 3 anion transport protein, Solute carrier family 4 member 1.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Detected in the erythrocyte cell membrane and on the basolateral membrane of alpha- intercalated cells in the collecting duct in the kidney.
Protein: CR5AB_BACUD
Sequence: MAILNELYPSVPYNVLAYTPPSFLPDAGTQATPADLTAYEQLLKNLEKGINAGTYSKAIADVLKGIFIDDTINYQTYVNIGLSLITLAVPEIGIFTPFIGLFFAALNKHDAPPPPNAKDIFEAMKPAIQEMIDRTLTADEQTFLNGEISGLQNLAARYQSTMDDIQSHGGFNKVDSGLIKKFTDEVLSLNSFYTDRLPVFITDNTADRTLLGLPYYAILASMHLMLLRDIITKGPTWDSKINFTPDAIDSFKTDIKNNIKLYSKTIYDVFQKGLASYGTPSDLESFAKKQKYIEIMTTHCLDFARLFPTFDPDLYPTGSGDISLQKTRRILSPFIPIRTADGLTLNNTSIDTSNWPNYENGNGAFPNPKERILKQFKLYPSWRAAQYGGLLQPYLWAIEVQDSVETRLYGQLPAVDPQAGPNYVSIDSSNPIIQINMDTWKTPPQGASGWNTNLMRGSVSGLSFLQRDGTRLSAGMGGGFADTIYSLPATHYLSYLYGTPYQTSDNYSGHVGALVGVSTPQEATLPNIIGQPDEQGNVSTMGFPFEKASYGGTVVKEWLNGANAMKLSPGQSIGIPITNVTSGEYQIRCRYASNDNTNVFFNVDTGGANPIFQQINFASTVDNNTGVQGANGVYVVKSIATTDNSFTVKIPAKTINVHLTNQGSSDVFLDRIEFVPILESNTVTIFNNSYTTGSANLIPAIAPLWSTSSDKALTGSMSITGRTTPNSDDALLRFFKTNYDTQTIPIPGSGKDFTNTLEIQDIVSIDIFVGSGLHGSDGSIKLDFTNNNSGSGGSPKSFTEQNDLENITTQVNALFTSNTQDALATDVSDHDIEEVVLKVDALSDEVFGKEKKTLRKFVNQAKRLSKARNLLVGGNFDNLDAWYRGRNVVNVSNHELLKSDHVLLPPPGLSPSYIFQKVEESKLKRNTRYTVSGFIAHATDLEIVVSRYGQEIKKVVQVPYGEAFPLTSSGPVCCIPHSTSNGTLGNPHFFSYSIDVGALDVDTNPGIEFGLRIVNPTGMARVSNLEIREDRPLAANEIRQVQRVARNWRTEYEKERAEVTSLIQPVINRINGLYDNGNWNGSIRSDISYQNIDAIVLPTLPKLRHWFMSDRFSEQGDIMAKFQGALNRAYAQLEQNTLLHNGHFTKDAANWTVEGDAHQVVLEDGKRVLRLPDWSSSVSQTIEIENFDPDKEYQLVFHGQGEGTVTLEHGEETKYIETHTHHFANFTTSQRQGLTFESNKVTVTISSEDGEFLVDNIALVEAPLPTDDQNSEGNTASSTNSDTSMNNNQ
What is the function of this protein?
Endotoxin with nematicidal activity.
What are the official names of this protein?
Pesticidal crystal protein Cry5Ab, 142 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryVA(b).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: GOG8R_HUMAN
Sequence: MAEETQHNKLAAAKKKLKEYWQKNRPRVPAGVNRNRKTNGSIPETATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERVLEVQIQTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQDMRWVEQLEWSLSKLKNQTAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEVASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPQPMPSVPEDPESREAMSSFMDHLKEKADLSELLKKQELRFIQYWQERCHQKIHHLLSEPGGRAKDAALGGGHHQAGAQGGDEGEAAGAAADGIAAYSNYNNGHRKFLAAAHNSADEPGPGAPAPQELGAADKHGDLREVTLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPGLGSNCCVPLFCWAWLPRRRR
What are the official names of this protein?
Golgin subfamily A member 8R.
What is the protein family that this protein belongs to?
Belongs to the GOLGA8 family.
Protein: SECA_CLOB1
Sequence: MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLKHYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNNEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYFTKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFTGRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARIDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMVTIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDKLGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNSHISGVEEEFQTELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYIRKEKEIGEEQIREIERVILLRVVDTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDEDSVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: EMTA_ECO7I
Sequence: MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQIKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: HIS41_PHOLL
Sequence: MIIPALDLIDGKVVRLHQGDYAQQRDYQHDPLSHFQQYEQQGAKLLHLVDLTGAKDPSARQIPLLRKLLAAVSIPVQVGGGIRTEEDVKTLLDAGANRIVIGSIAIKQPALVTQWFKRYGAENIVLALDVRINDTGMKQVAINGWQENSSVTLEQVIEQYLPCGLKYVLCTDISRDGTLTGSNVELYRAICQYYPQIVFQASGGIGTLNDIASLPTSGVAGVIIGRALLDEKFTLKEAIQCWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_MYCTA
Sequence: MTVAAGAAKAAGAELLDYDEVVARFQPVLGLEVHVELSTATKMFCGCTTTFGGEPNTQVCPVCLGLPGSLPVLNRAAVESAIRIGLALNCEIVPWCRFARKNYFYPDMPKNYQISQYDEPIAINGYLDAPLEDGTTWRVEIERAHMEEDTGKLTHIGSETGRIHGATGSLIDYNRAGVPLIEIVTKPIVGAGARAPQIARSYVTALRDLLRALDVSDVRMDQGSMRCDANVSLKPAGTTEFGTRTETKNVNSLKSVEVAVRYEMQRQGAILASGGRITQETRHFHEAGYTSAGRTKETAEDYRYFPEPDLEPVAPSRELVERLRQTIPELPWLSRRRIQQEWGVSDEVMRDLVNAGAVELVAATVEHGASSEAARAWWGNFLAQKANEAGIGLDELAITPAQVAAVVALVDEGKLSNSLARQVVEGVLAGEGEPEQVMTARGLALVRDDSLTQAAVDEALAANPDVADKIRGGKVAAAGAIVGAVMKATRGQADAARVRELVLEACGQG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.