PharMolix/UniProtQA huggingface dataset:
Protein: GILT_RAT
Sequence: MSCSPLVPFLSLLLLLFLPEVPRAATASLPQGSSEGAATCKAHDLCLFGPRRLLSAPPVNVSLYYESLCGACRYFLVRNLFPTWLMVMEIMNITLVPYGNAQERNVSGTWEFTCQHGELECKLNKVEACLLDKLEKEAAFLTIVCMEEMEDMEKKLGPCLQLYVPEVSPESIMECATGKRGTELMHENAQLTDALQPPHEYVPWVLVNEKPLTDPSQLLSSVCELYQGTEKPDICSSMADAPREVCYK
What is the function of this protein?
Lysosomal thiol reductase that can reduce protein disulfide bonds.  May facilitate the complete unfolding of proteins destined for lysosomal degradation.  Plays an important role in antigen processing.  Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds.  Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation (By similarity).
What are the official names of this protein?
Gamma-interferon-inducible lysosomal thiol reductase, Interferon gamma inducible protein 30.
What is the protein family that this protein belongs to?
Belongs to the GILT family.
What are the subcellular locations of this protein?
Secreted. Lysosome.
Protein: RS8_MYCLB
Sequence: MTMTDPIADFLTRLRNANSAYHDEVTVPHSNIKANIAQILKNEGYIRDFRTEDARVGKSLIIQLKYGPSRERSIAGLRRVSKPGLRVYAKSINLPRVLGGLGVVIISTSSGLLTDRQAARQGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PRL_FELCA
Sequence: MDNKGWSLKGSLLFLLLLLSDLLLCKSVASLPICPSGAVNCQVSLRDLFDRAVILSHYIHNLSSEMFNEFDKRYAQGRGFITKAINSCHTSSLPTPEDKEQAQQIHHEDLLNVILRVLRSWNDPLYHLVTEVRGLHEAPDAILSRAIEIEEQNRRLLEGMEKIVHQVHPGVRENEVYSVWSGLPSLQMADEDSRLFAFYNLLHCLRRDSHKIDSYLKLLKCRIVYDSNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RCCD1_MACFA
Sequence: MAEERPGAWFGFGFCGFGQELGSGRGHQVHSPSPLRAGVDVCRVSASWSYTAFVTRGGRVELSGSASGAAGGCRDAWASEGLLLVLRAGPGPEALLQAWAPDSALRGEPLWAHSVVPEAVEEDDPGGEAQIGRLPLLPCARAYVSPRPPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGLTMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATGLNEDGSQVKRTGRVEDGAPAPFIAVQPFPALLDLPLGSDAVKVSCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDWPRRVEYFVDKQLQVKAVTCGPWNTYVYAVEKGKS
What is the function of this protein?
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8.  Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation.  Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.
What are the official names of this protein?
RCC1 domain-containing protein 1.
What are the subcellular locations of this protein?
Chromosome. Note=Colocalizes with trimethylated 'Lys-9' of histone H3 (H3K9me3).
Protein: GARL_ECOLC
Sequence: MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEKAELAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: 106L_IIV6
Sequence: MPICVLRKSPKRRSPSPKRRRSPKRRSPRRSPRRSPRRSPPRRRSPRRSTRRSPRRR
What are the official names of this protein?
Uncharacterized protein 106L.
Protein: ATG26_CRYNB
Sequence: MSPPISPTPPPLQPPFPPTAIARGPDRPDPPPQHQQAAESLVNAAAQHVAPTCPPTSDELPQMEDQATNSSNDSLIPSRQAPNQEETENAITAGTPPDEMEPTKDAQTVRFSSSSPASYSTHEYPTEEINEPRTSSRAPNTASSQMAESSFDFRSSRDIGSIRMGASALVSALNALPWEEDDDSDDGEDDDEFIEPARGSSSTIYERKQRPQTPSTSHGFHPTHTLHFPFRQNAIARRACQPGTTELDYQYATPETSSRRTSAAGSESSSEGEVPLPKGFVSHPNLIVPSGEGEAAAHPDPKLISDRITKEQQIADVEEQAEILRSAEEQEMRLGKEFVPPKSRDSADLNVDAALREGGSEREDVIEEQMQTNEAEKRLTRNEKLAERLMEVFGLEEREEVLEEMKCWLLRSVMLKGYMYLTKRHICFFANMPNENNLLVKSGPLHKKASRSKLNTKFWVVLKNDVLSWYESTSDPYFPKGNISLQYCHSCDAVSGTRFKVRTSERNYTFTADTESSRDEWVKAIQKVMFKTQHEGETIKLIIPLEAIVDVEKSPTLEFTETIEVKCIDAEDQMSVDSYFFASFPDNDYAFSAIQKLVRERPSPPELPRISSVTTIHANQEPLDTSHATIKRHGTDSSAEKLGMASHRPFRKISSVLKPLILKSSDGEPLEEHSQGPHHNDEDASHLPHIEAISNRRRSEEESDNDYFDGYPPRQVGPPPPSMNDDARNWRPSWIRKPASKLFGSSPSGSFVSHPGRLPTDSSTTVTESGPSLRSRTGRTKQASVTEVIEPPIQYEEEVSEDEMSNKPSVVDSNSAETARKRAARLSWTSETSSGSQMVKSKSDFSMLGSESGHSESAETVRKFRTFFALSDKEELIDHFPGYLYRVLPVSGRFFISTNYFCFRSSQLLYKTKESFRLMIIPIRDLYGLKAQKAFRFGHSGLTVVIKGHEEIFIEFRSASRRKACIALLEERMEAVRLSGENTIVDSHKIEARIMEDLDESTPVEPKSPWPVSPSPLFGSTTSTSFLEFKPEPMKITCLTIGSRGDVQPYIALCKGLQAEGHITKIATHGEYKAWVEGHGIAFESVGGDPAELMQMCVDNGMFTVSFLKEGLQKFRGWLDDLLNSSWEACQGSDLLIESPSAMSGIHVAEALRIPYYRAFTMPWTRTRAYPHAFAVPEHGRGGPYNYMTYTMFDQVFWRAISGQVNRWRRNVLGLDATTFDKMEQHKVPFLYNFSPTVVPPPLDWTEWIHVTGYWFLDKADEKQGEKSWTPPQGLVDFIDKAHGEEKKVVYIGFGSIVVSDPEEMTRCVVEAVVNSGVCAILSKGWSDRGSKKGEPKGDSEGADGVKYPPEIFAIDSIDHGWLFPRIDAACHHGGAGTTGASLRAGIPTIIKPFFGDQAFWAERVESLNVGSSIRRLTSHQLASALIKATTDEKQISKARVVGEMIRKENGITRAIEAIYRDLEYAKSIIKSLPSTDDRTPERISSLLHPLTTADLSFNRVRSRSRSRSRSSQGRFSPRRHTVDDDGWSVVSGGSRSRSGSASAVTSPERRPLNIGSALGSHVFKTALLPNTFGKWRNLEEGDDR
What is the function of this protein?
Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity).
What are the official names of this protein?
Sterol 3-beta-glucosyltransferase, Autophagy-related protein 26.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: LUXS_FINM2
Sequence: MNKIESFKINHLKLMPGIYVSRKDYLGNEVLTTFDLRITAPNREPVMNTAEVHAIEHLGATFLRNKLENEVIYFGPMGCRTGFYLILVGDKKSEDIVDLIKELFEFISNYEGEIPGQSAKDCGNYSDMNLSMAKFYSNKYLNVINNIKKENLIYPE
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: YIDD_RHOPA
Sequence: MQLPSRGTDWIAQVLRLPRNAGRGLIWLYRHTLSPLVGYNCRHYPTCSMYGDEAIRKFGLWAGGWMTLARLLRCQPWGTSGIDLVPQTAPSRARWYLPWRYARWRGVNAPPPDVAEPCGCGSHSQLTPH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GRAR_STAAT
Sequence: MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDQTIFLSKTEMIILEILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Upon phosphorylation by GraS, functions as a transcription regulator by direct binding to promoter regions of target genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Response regulator protein GraR, Glycopeptide resistance-associated protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_LISMH
Sequence: MEFDRMLIRYGELSTKGKNRKQFVTKLAQNVKRAMTDLPEVRIHGERDRMYIILNGADYQLAEERLKPIFGIQSFSPAVRVNLDLEEVKAAALALVQDAHEENGTFKVAARRSHREFPLDSNEINQEIGAHVLQNIEDLTVNVKNPDVKLTIDVRKEGVFLSCRTILGAAGLPVGSSGRAMLMLSGGIDSPVAGYLAQKRGVEIEAVHFHSPPYTSEQAKQKAIDLAAKLAKYSGQVQMHIVPFTEIQEVIKQQIPESVIMTVTRRMMLRITDELRRKRNGLAIVNGESLGQVASQTLESMLAINAVTATPIIRPVVSMDKNEIIQIAQKIDTYNLSVQPFEDCCTIFTPPSPKTKPKLDKIEHYESFTDFDALIAKALDNIETISVNVAETVQVKDEFADLF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA1_LISMO
Sequence: MEKTIAINAGSSSLKFQLYDMPSERVITAGIVERIGLKDSIFTITVDGEKIKEIIDIPDHEIAVQMLLEKLINHKVIGSYDEITGIGHRVVHGGERFPESVYIDDQVIKDIEALSELAPLHNPANVTGIKAFRKILPDVVSVAVFDTAFHQTMPPASYLYSLPYSYYEDYGIRKYGFHGTSHKYVSERAAELLGRPVEELRLLTCHLGNGASIAAIEGGKSMDTSMGFTPLAGVSMGTRSGNIDPALIPFIMEKTGKTAEQVLDVLNKESGMLGVSGISSDLRDLEDEAAKGNDRAELALQVFVDRIHKYIGSYAARMNGVDAIIFTAGIGENSSYIREKVLRGLEFMGVYWDPALNQVRGEERFLNYPHSPVKVIIIPTNEELMIARDVETIKNNR
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase 1, Acetokinase 1.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_MYCBP
Sequence: MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RL17_XYLFA
Sequence: MRHQKSGRKFNRTDAHRGAMFSNMVASLFKYQLIKTTLPKAKELRRVAEPLITLAKVDSVANRRLAFARLRNKEAVGILFSNLGPRYVTRPGGYIRLLKCGFRHGDNAPMAYVEMLERPIIAEEVT
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GMF_DROME
Sequence: MSDNQICDISNEVLEELKKFRFSKSKNNAALILKVDREKQTVVLDEFIDDISVDELQDTLPGHQPRYVIYTYKMVHDDQRISYPMCFIFYTPRDSQIELQMMYACTKSALQREVDLTRVYEIRELDELTEEWLKAKLK
What is the function of this protein?
Inhibits Arp2/3-mediated actin nucleation (PubMed:25308079).  Together with flr, promotes Arp2/3-nucleated actin filament array disassembly (PubMed:25308079).  Promotes debranching (PubMed:25308079).  Regulates lamellipodial protrusion dynamics possibly by facilitating lamellipodial retraction (PubMed:25308079).  In egg chambers, enhances the retraction dynamics of cellular extensions in border cells and thus together with flr plays an important role in directional migration of border cell clusters (PubMed:25308079).
What are the official names of this protein?
Glia maturation factor.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. GMF subfamily.
Protein: HAOX1_HUMAN
Sequence: MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLAVSKI
What is the function of this protein?
Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate (PubMed:10777549, PubMed:17669354, PubMed:18215067, PubMed:10978532).  The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones (PubMed:10978532, PubMed:17669354).  Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, albeit with much lower catalytic efficiency (PubMed:10777549, PubMed:17669354, PubMed:18215067).  Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2 (PubMed:10777549, PubMed:17669354, PubMed:18215067, PubMed:10978532).  Is not active on L-lactate and 2-hydroxybutanoate (PubMed:10777549).
What are the official names of this protein?
2-Hydroxyacid oxidase 1, HAOX1, Glycolate oxidase, GO, GOX, Glyoxylate oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: IF1AX_PONAB
Sequence: MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDDI
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 1A, X-chromosomal, eIF-1A X isoform, Eukaryotic translation initiation factor 4C, eIF-4C.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: Y4278_RHOPS
Sequence: MSTSQPDDSNNRIVAVTLDEESIGRSGPDIEHERAIAIYDLVEKNLFAPEGAGDGPFTLHIGITGSRLMFDIRREDGAPVITHLLSLSPFRRIVKDYFMICDSYYQAIRTATPDKIEAIDMGRRGIHDEGSRTLQERLSGKVRIDFETARRLFTLISVLHWKG
What are the official names of this protein?
UPF0262 protein RPD_4278.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: RL31_NITOC
Sequence: MRQDIHPKYSEITVTCSCGNSFSTRSTAGKDFHIEVCSACHPFYTGKQKLLDTAGRVDKFRQRYNLKS
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RISB2_BRADU
Sequence: MDPPAIEHPRFAKPQRVAFVQACWHRDVVEEARIAFMKEAEARHLTHVDVFEVPGSFEIPLHAQILAKTRRYTAIVAAGLVVDGGIYRHEFVADTVIKALMDVQLRTEVPVFSAVLTPQQFHETEVHYDFFRRHFAIKGVEVAEACANTLLGLERLRGQVAAGIA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase 2, DMRL synthase 2, LS 2, Lumazine synthase 2.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MMP21_CYNPY
Sequence: MPTAPALGALLLLLGALTPGHQEKLFHSRDHSDLQPSPQHQAELVTDLQSAQQFLSKYGWTEPVKWEGTSSKNAAELPRYGDADLMQEGASISRYGQEFPLEPTQAPAFVEALRKFQTLNGLPATGKLDDSTIAAMNKPRCGVPDNQIGKESAIVKSNSNNVTEKASGKSLNTTTNQNPENGTSTSKIRKKRFLQMLAAPVRYKDQANQGSTVRGAFSKKLLKWRLIGEGYSSQLSIDEQRYVFKTAFRMWSEVMPLDFEEDLTSPMSLIDVKLGFGRGRHLGCTRSFDGSGQEFAHAWFLGDIHFDDDEHFTAPSSDSGISLLKVAVHEIGHVLGLSHIYQTGSIMQPNYIPQEAGFELDWTDRKAIQMLYGTCEGSFDAVFDWIWKERNQYGELVLRYNTYFFRNAWYWLYENRKNRTRYGDPVTVSLGWHGIPAEGIDAFVHVWTWTEDATYFFKGTQYWRYDSENDQAYIKDAQGNQYPRLISEGFPKIPSPINTAFFDRRDQFIYFFKDAHVYAFDVKRNMVANHYPKRIIDVFPAVVRNNHPFGNIDAAYYAYTHNSIFLFKGKEYWKVVSDKDRQQNPKLPRNGLFLKKNISEQWTDICNVHSSMLKMR
What is the function of this protein?
May play a role in gastrulation-related cell movement (PubMed:11606053).  Plays a specialized role in the generation of left-right asymmetry during embryogenesis.  May act as a negative regulator of the NOTCH-signaling pathway (By similarity).
What are the official names of this protein?
Matrix metalloproteinase-21, MMP-21.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRF_SHISS
Sequence: MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDVQKLTDAAIKKIEAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
Protein: RLMN_XYLFM
Sequence: MNGFAVIPSVTTTTTSGEPIASDVARKQNLLELDREGLERFFEDVLGEKRYRAHQVMKWIHHRYVADFEQMTDVGKALRTRLQACAEVRVPRVVFDKHSADGTHKWLLAMGTDRKNAIETVYIPDKGRGTLCVSSQIGCGLNCTFCSTATQGFNRNLTTAEIIGQVWVAARHLGNVPHQRRRLTNVVMMGMGEPLMNFDNVVRAMSVMRDDLGYGLSNKRVTLSTSGLVPMIDRLSTESDVSLAVSLHAPNDKLREQLVPLNKKYPIVELMASCERYLSVNRKRDSVTFEYTLMKGVNDKQEHAHELAKLMRQFDCAMQVKGAAKVNLIPFNPFPGTCYERSTEVDIRAFQKILLDAQILAMVRRTRGDDIDAACGQLKGQVVDRTRRQAEFRRTIEDRVGRDVAA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_SHEAM
Sequence: MAIERTFSIIKPDAVAKNHIGAIYNRFESAGLKIIAAKMVHLTKEQAEGFYAEHSERPFFGALVSFMTSGPIMVQVLEGENAVLANREIMGATNPAQAARGTLRADYAASIDENAVHGSDALASAEREIAYFFAADELCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_HISS2
Sequence: MQSSPLLENLIEHLRCLPGVGPKSAQRMAYHLLQRDRSGGMNLAGALTEAMSKIGHCTHCRTFTEEESCAICNNPRRQNSGFLCVVEQPSDIPAIEQTGQFSGRYFVLMGHLSPLDGIGPKEIGLDLLQKRLQHESFYEVILATNPTVEGEATANYIAEMCFQHNIKVSRIAHGIPVGGELETVDGTTLSHSLIGRREIQL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: METE_RUTMC
Sequence: MVTIHNLGFPRIGRHRELKFALEKYWSNAISQDELLQTASTLCKQYWQNQNKLDWVPVGDFSFYDHVLDMSFLLGNIPKRAENLSDNELDNYFRVARGRAFINESERTCIQAGEMTKWFDTNYHYIVPEFSQETNFALQAQRLIAQIRQAQAQGVKVKPVVIGPVTYLWLGKSKDKINKLDLLDSLVKVYTQLFDELVKLGIEWIQVDEPILVTELETDWQVAFRKAYDILANSPIKLLLVSYFGTLQDNLSFACGLPIDGLHIDAINAKDEVQLLIDSLSDDKILSLGVVNGRNIWKTDLSTTLLWLEPIHQQLQNRLWLAPSCSLLHVPVDLDSEQELNDDIKSWLGFAVQKLEELSLLAQALNQGQASVTKEIANNIDAINSKKYSPLVHNAKVKERIAKVNDELGNRQSDYKSRTKLQSEKFNLPLYPTTTIGSFPQTLEIRQARHDYKLGKLSAEQYMQTMRSEIRYCVQVQEHLGLDVLVHGEPERNDMVEYFGQQLSGYVFSQFGWVQSYGSRCVKPPIIFGDIFRPKPMTLDWITYAQSLTNKPMKGMITGPVTMLNWSFVRDDQPRATTCLQLSLAIRDEVLDLEKSNINIIQIDEAALREGLPLRKSQWQTYLDWAIRAYRVSANGVSDETQIHTHMCYSEFNDIIEAIAQMDADVITIETSRSDMELLDIFDEFDYPNEIGPGVYDIHSPNIPSVDSIVELMQKAAKYIPIKRLWVNPDCGLKTRHWDEVNLALTNMVLASQQLRKN
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: FBK86_ARATH
Sequence: MAFSFDLAVIFQRERRMKRKSRVTIRRRRRRDMCKSHEPMPYIPFDLVIEILTRLPAKSLMRFKSVSKLWSSLICSRTFTNRLLRVPSFIQRLYVTLTFLDNSLQRKSKLLSSSSSPGSDISTMSSFVVDRDLTTPSMKGYYLSHVLRGLMCFVKEPSVKIYNTTTRQLVVLPDIEESNIIAEDHKNKKIMYRIGHDPVGDQYKVVCIVARPNDEFGELRRYLSEHWVFILGGDKSSGWRKIPCPSPHLPITQILSINGRMHYLAWVQKFDPMLVTFDFSSEEISILQAPEDIRWFKSNPIEYYGKVALLNLSDLKRECTMNLWVMEDVEKNMWSEKTLVVHPSQMDIVKSTSLRVAGTTRNNEVILVPHNIRYTLTGEVIVEPQNTTLLYIFLYDLQKNLMRKVEIKEPPYHTKFWDVVGLDDVENFMYL
What are the official names of this protein?
F-box/kelch-repeat protein At4g19930.
Protein: LRRT3_RAT
Sequence: MGFNVIRLLRGSAVAVVLAPTVLLTMLSSAERGCPKGCRCEGKMVYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYMQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLKSFKGLRENTILCASPKELQGVNVIDAVKNYSICGKSTTTERFDLARALPKPTFKPKLPRPKHESKPPLPPTVGASEPSPETDVDTEHISFHKIIAGSVALFLSVLVILLVMYVSWKRYPASMKQLQQRSLMRRHRKKKRQSLKQMTPGTQEFYVDYKPTNTETSEMLLNGTGPCTYSKSGSRECEIPLSMNVSTFLAYDQPTISYCGVHHELLSHKTFETNAQEDTMESHLETELDLSTITSAGRIGDHKPQLA
What is the function of this protein?
May play a role in the development and maintenance of the nervous system (By similarity).  Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation.
What are the official names of this protein?
Leucine-rich repeat transmembrane neuronal protein 3.
What is the protein family that this protein belongs to?
Belongs to the LRRTM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane; Single-pass type I membrane protein.