PharMolix/UniProtQA huggingface dataset:
Protein: TRMA_PSEF5
Sequence: MTFDAASYTTQLNDKVARLRDLLAPFDAPEPQVFDSPLQNFRLRAEFRLWREAGERHYAMFSQDDKRTPILIEEFPIASQRINQLMPRLKAAWQASAPLSHKLFQVEFLTTLAGDAMITLCYHRPLDEHWHKAASQLAADLKVSVIGRSKGKREVIGQDYVVEKLEVGGRTFSYRQPEGAFTQPNGTVNQKMLNWAYEALGERQDDLLELYCGNGNFTLPLATRVRKVLATEISKTSVNAALSNLSENAVDNVTLVRLSAEELTEALNEVRPFRRLQGVDLKSYEFGSVFVDPPRAGMDPDTCELTRRFDNILYISCNPETLAANIAQLHDTHRITRCALFDQFPWTHHMESGVLLTRR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: MTNA_KLEP7
Sequence: MQTLQTTSLRVSENQLFILDQQALPQETRWLAADNVALLVDHIHTLRVRGAPLIGLSASLLLALLAQRGLNRDALQQALETLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCARIAEAGSALVKPGSRLLTHCNTGGLATAGVGTALGVIALAHRQGKVTNVWVDETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKIGTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPTGAAVYNPAFDVTPAGLISGWVLDSGVVTPAQVAAGAFAPDNG
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: PVDQ_PSEPK
Sequence: MPVFPFCRPMTCAGLAAALVAFSVGVQAQPAPADASAQIRYTRYGVPHIVAKDERGLGYGVGYAYAQDNLCLLANEVLTVSGERSRYFGAKGQTLEQRDNLASDLFFTWLNSPAAVDAFLQAQPASVQALLAGYASGYNRALVERRRQGLPAECGDGEWVRPISSQDLVKLTRRLLAEGGVGQFVEALAGAQPPTLARAQSSAGFASALARQERFAAERGSNAVAVGAQRSANGRGLLLANPHFPWMGGMRFYQMQLTIPGQLDVMGAALPGLPVVNIGFNQHLAWTHTVDTSKHFTLYRLQLDPKDPTRYVLDGKSLPMARQTIRVAVKGTDGSLSQIERQVYSSQFGPVVQWPGRLDWDAQAAYSVRDANLENSRVLQQWYQINRADSLAALKGSVEQLQGIPWVNTLAVDQGGRALYLNQSVVPYVDQQLLDTCSNPQAQGRLVVLDGSRSACQWKVDAQAAQPGIFPARLLPSLEREDFVQNSNDPAWMANPAQPLTGYSPLVSRNDQPLGMRGRFALQRLQGKARLGVDELQRMVTDEEVYLASLVLPDLLQWCKGASADVQAVCSSLAAWNGKADLDSGMGLVHFQNLFNALAEHPESWRVAFNPADPQHTPRGLAVEQAAVSRLVHQAALASLKQVSESGVAGAARWGQVQQALDGTPVPGGPQALGVYNAIYSVPHGQGKRLVVSGTSYLQLVSFTDKGPEARGLLAFSQSSEKASAHASDQTKAFAAKQLALIPFTEAQIKADPEYREVVISERDKGAVVSQP
What is the function of this protein?
Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid.  Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length) (By similarity).
What are the official names of this protein?
Acyl-homoserine lactone acylase PvdQ, AHL acylase PvdQ, Acyl-HSL acylase PvdQ.
What is the protein family that this protein belongs to?
Belongs to the peptidase S45 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RIMM_EHRCR
Sequence: MENDLICLGVITSSHGISGHVKIKTFTENPEDFTSYGTLTDGINTYEVEIISIISQNIIIAQIKGIVSRTDADLLRNKKFFVEKNKLPNPTNDDEFYYSDLIGLNVVLENNNVYGNIKKIHNFGSCDIIEIRLSNSKKSTMLPFTKDIFPYVNVKEKYIIITLPEVIGNNSDIQR
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXZL_BACSU
Sequence: MAVSQLMQNLTKQLLHVRERKTDVMQEGETAKELNYEGEDMQATSSAQNRQTSV
What are the official names of this protein?
Uncharacterized protein YxzL.
Protein: IF2P_METB6
Sequence: MSDPKIRTPIVCVMGHVDHGKTSLLDRIRGSSVVASEAGAITQHIGATIVPIEAIRKMSGSMEKIPINIPGLLFIDTPGHHAFTTLRARGGALADMAILVVDISQGFQPQTIEALQILRNCKTPFVIAATKVDRIHGWRINKDESFLSSFGKQNERVKTDIETKTYEIVGKLSDLGFSADRYDRVSDFQRNLAIVPVSAHTGEGIADLLMIMIGLAQRYMGEELKLSAEGPGEGTVLEVKEERGLGTTLDVILYNGTLSVGDEIAMASQDDVVTTKVRSLLKPRPMKEILIEDRFERVKSVVAASGIKVSAPGLEKVIAGSPLFVTRGNMDELAARIRKEMQEIHVNLAEEGIVIKADTIGALEALCKELESKEIKVMRAQVGPVSRHDLIDTETIKNPTFRVLLSFNTPILPDAADMIKDPLYTQVKVFSGQVIYQLIDQYVAWRDEQKRIAEKAQFEHVMMPAKIRLLPDCVFRQSNPAVVGVRVLGGKLRADVDLVKTDGKKIGHLKTMQLRQESIKEADAGLEVAISIEGATVGRQLNVGDDLLVDLPERHVKVLEREMLKNLNISTQEVLAEFVAIRRKAEPFWGK
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: ALR_NITEC
Sequence: MYRPIRALIDCTALQHNLSVVRSHTRQARIMAVVKADAYGHGLLRTTQALNTADGFAVLELEAAIQLREAGFNQPVLLLEGFFSAEELEAIDHYQLSTVIHSHEQLSLLLAHRKTGKPDIYLKINTGMNRLGFRPEEESYVFNRIRQWRSDTSITLMTHFSCADDALEADQVNQQLDQFAALHDVKENNLPQTLANSAAILRYPGTHADWVRPGIVLYGASPLPDKTGIELGLRPVMTLTSQIIAVQQLDPSDRVGYGGQFIANQPMRIGVVAAGYADGYPRHAPTGTPVLVNGQRTRLVGRISMDMLTVDLNGISEAGVGSPVTLWGEGLPVEEVAKSAQTISYELLTALSPRVPSISIS
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: MSCL_CAUVN
Sequence: MSVVKEFREFIARGNVIDLAVGVIIGAAFNGIVKSLVDQVIMPPIGLLTGGLDFSKLEWVLRPEDPASEAIEKVAIQYGAFVNTVIQFFIVATVVFLLVKLVNEIRRQDAAEPAPAAPPAPTAEETLLTEIRDLLAKKG
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBL_AFRGR
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEENQYIVYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFCFCAEALFKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVEARNEGRDLAREGNEVIREASKWSPELAAACEVWKEIIFEFETIDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TSAD_BUCAT
Sequence: MRILGIETSCDDTGIAIYDTNKGLLINEIYNQRKLNNIYGGIIPELASREHMEAMIVLLNKIFKKKNIYKYVDMIAYTAGPGLIGSLLVGATFACSLGLSLNIPVLPVHHMEAHLLSPMLDYKTIQFPFIGLLVSGKHTQIIGAHKFGEYEILGNCLDDAAGEAFDKTAKLLGLKYPGGLELSKLASKGIKDYFYFPRPMIHHSDLNFSFSGLKTFAAQTIKKSSKSMQEKANIAKAFEDAVIDILLIKTKKALKKQKWKRLVIAGGVSANQKLRKKSEIMVKKNFNGTVFYSSLEFCTDNAAMIAYLGSLRQKEARNSQLEILVKPKWSIDDLCF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_DELAS
Sequence: MKRTYQPSKTRRARTHGFLVRMKTKGGRAVINARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: VDH_AMYS7
Sequence: MSFLDDEKWTGRVFTGSWERAAGGDAAVIEPATGDELGRVGIASPQDLAASAAKAAEAQRAWAATSFQERAAVLRRAGDLWQQHAAELKDWLIRESGSIPGKADFELHVAAQECYEAAALPSHPTGEVLPSEAPRLSMARRVPAGVVGVIAPFNAPLILSIRSVAPALALGNSVVLKPDPRTAVCGGVALARVFEEAGLPAGVLHVLPGGPDVGAALVEDKHVRVISFTGSTAAGRAVGESAGRHLKRAHLELGGNSALIVLDDADLEQAMSAAAWGSFFHQGQICMTTGRHLVHASLYDEYVDRLADKASHLPVGNPFTEQVALGPIIDAKQRDKIHGLVTSSVDAGAKVAAGGTYEDLFYRATVLAGAGPSVPAYDQEVFGPVAPVAKFTSLDEAAKLASESEYGLSLGIITADVAKGLALADRIPTGIAHINDQTVNDEALAPFGGVFDSGTGSRFGGPAANIEAFTETRWVTMRGDVAGYPF
What is the function of this protein?
Catalyzes NAD(+)-dependent oxidation of vanillin to vanillate.  Oxidates also other aromatic aldehydes including benzaldehyde, coniferyl aldehyde and cinnamaldehyde, but has a preference for vanillin.  Not active with NADP(+) (PubMed:23064333).  Involved in the degradation pathway of lignin-derived aromatic compounds of plant cell walls.  Catalyzes the conversion of vanillin to vanillate due to toxicity of vanillin to the cells (Probable).
What are the official names of this protein?
Vanillin dehydrogenase, Benzaldehyde dehydrogenase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: SYY_NITMU
Sequence: MTIPISEQIEIIKRGCSELLLEDELEQKLAQNRPLRIKAGFDPTAPDLHLGHTVLLNKMRHLQDLGHHALFLIGDFTGMIGDPSGKNTTRPPLSREQVAENAKSYQDQVFRILKPEQTEVVFNSAWMDRLNAADLIKLAATHTVARMLERDDFGKRYQSNKPIAIHEFLYPLIQGYDSVALRADIELGGTDQKFNLLMGRELQKHFGQASQCVITMPLLEGLDGVNKMSKSAGNYIGITESPGNMFGKLMSISDELMWRYIELLSFEPLRVVRQWQQDVGNGRNPRDIKVLFAQEIVTRFHSRQDAEAALADFESRFRRGGIPDDLPENILQAGKEGLPIAQLLKQTGLTASTTEALRMIEQGGVKLNGEKVSDKTFRLSCGQMVIVQVGKRKFARVTICEEK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALM_NEUCR
Sequence: MADSLTEEQVSEFKEAFSLFDKDGDGQITTKELGTVMRSLGQNPSESELQDMINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQLMMQK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: LGT_ACIB5
Sequence: MLTYPNIDPVAIHLGPLQVHWYGLMYLLAFLCAWGLASYRAKQRDGWTSDMVSDLVFYGALGVVLGGRIGYVLFYEFDKFLENPIWLFQVWTGGMSFHGGFLGVMIAMLFWCKKYQKTWFQTLDFVAPCVPTGLMFGRIGNFIGGELYGRAVTDPNYPFGMIFPTDPLHLVRHPSQIYQALCEGLLLFIILWWFSSKPRPRMAVSALFLMGYGVARFVMEFFRQPDADQGFILFGWMTKGQILTVPMLLIGLWMMWYAYQKKIYDWGPQKNS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEUC_CAUVC
Sequence: MSGKTLYDKIWDAHVVSEAGGEAILYIDLHLIHEVTTPQAFAGLRAAGRKVRRPDRTLAVADHNIPTEGQALGVDAVADEEARLQLKTLARNVADNGIEFFPMGDIRNGIVHVVGPEQGRTQPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLRQKKAKNMLVRVDGQLPPGVTGKDVALAVIGEIGTAGGTGYVIEFAGEAIAGLSMEGRMTLCNLTIEGGAKAGLVAPDDKTFAYIQGKPAAPKGAAWDMALSHWKTFFTDEDAVFDRTVVIDGSALVPMVTWGTSPEDVIPVTGNVPDPESFATPDKRAAAHRALDYMGLKAGQPISEARIDRVFIGSCTNSRIEDMRAAAAVVQEAFLHGRLVAPHVKAMVVPGSGLVKEQAEEEGLDAIFKAAGFDWREPGCSMCLAMNPDKLAPQERCASTSNRNFEGRQGRAGRTHLVSPAMAAAAAIAGHLVDVRTLFSETAQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CHSY_EQUAR
Sequence: MTVLEESADASSRRLAQRANGPATVLAIGTANPANVFEQSSYPDFYFDITNSQHMTELKLKFSRMCQKSGIKKRYMHLNSEILKANPSLCAYWEKSLDVRQDIAVVEVPKLGKEASLKAIKEWGQPKSKITHLVFCTTSGVDMPGADWALTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDVAENNKGARVLVVCSEITCVTFRGPSETHLDSLVGQALFGDGAAAVILGSDPLPEENPCFELHWSGSNILPDSDGAIDGHLREVGLTFHLMKDVPGIISKNIGKVLNDAFRSAFDESGNAEDRPASVNDIFWIAHPGGPAILDQVEEKMKLAPEKMRATRDVLSEYGNMSSACVLFIMDHMRRMSAQNKLQTTGEGLDWGVLLGFGPGLTVETVLLKSIRLAC
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase, Naringenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: MSRP_SALG2
Sequence: MKKIRPLTEADVTAESAFFMQRRQVLKALGISAAALSLPSTAQADLFSWFKGNDRPKAPAGKPLEFSQPAAWRSDLALTPEDKVTGYNNFYEFGLDKADPAANAGSLKTEPWTLKISGEVAKPFTLDYDDLTHRFPLEERIYRMRCVEAWSMVVPWIGFPLYKLLAQAQPTSHAKYVAFETLYAPDDMPGQKDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPIRLIVPWKYGFKGIKSIVSIKLTRERPLTTWNLSAPNEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYANEVASLYRGLNLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: RL24_CAMJE
Sequence: MAVKLKIKKGDSVKVITGDDKGKTGKVLAVYPKTLKVVVEGCKIAKKAIKPSEKNPNGGFINKEMPMDISNVAKVQE
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL31B_STRZP
Sequence: MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: ACSA_HALHL
Sequence: MSETKVYPVPETIQRDAHLNFEQYQEMYNRSIQDPEGFWSEQADKFLDWFSKWGTTCHWDLAKGDIRFFEGGTLNVAYNCVDRHLETRGDQTAIIWEGDEPDQDEHITYRDLYERVGRLANALKARGVKKGDRVCIYLPMVPEAAVAMLACARIGAVHSIVFGGFSPEALRDRIQDADAEVVITSDEGVRGGRSIPLKANTDKALEGCPNVKTVFVVRRTGGDIAWNDGRDVWFHEACAEASPDCPPEHMDAEDPLFILYTSGSTGKPKGVQHSTAGYLLGTAMTHKYIFDYQDGEVYWCTADVGWVTGHSYIVYGPLANGAKTLMFEGVPTYPDAGRFWQVVDKHEVSIFYTAPTAIRALMGQGDDHVKKTSRKSLRILGTVGEPINPEAWEWYYHTIGEDRCPIVDTWWQTETGSILIAPLPGAMDLKPGSATLPFFGVEPQLVDDKGNVLEGATNGNLVINRAWPSMMRTIYGDHERFFNTYLAAYPGKYFTGDGARRDEDGYYWITGRVDDVINVSGHRMGTAEVESALVLHDKVSEAAVVGYPHDVKGQGIYAYVTLMAGEEPSDELKQELVKLCIQEIGPIAKPDIIQFAPGLPKTRSGKIMRRILRKVASNELDSLGDTSTLADPTVVDTLIEDRANQ
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: LSPA_SHEB5
Sequence: MPLTWKDSGLRWYWVAVLVFFADQLSKQWVLANFDLHESLNLLPFFNFTYVRNYGAAFSFLSDAGGWQRWLFTIVAVGFSTLLTVWLRRQSASLLKLNLAYTLVIGGALGNLVDRLMHGFVVDFIDFFWAKSHYPAFNIADSAICIGAVLIIWDAFLSGKSETDSAEGVKK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPIA_VESOH
Sequence: MTQDEMKFTVAQTALKYVIKNTIIGVGTGSTANFFIDALSTIKNNIKGAVASSKATAQRLENHGIRVFDLNKVTAISTYIDGADESDNNLNLIKGGGGALTREKIVAAVAHQFICIADESKLVSIMGSFPLPIEVIPMAANYVKNQISQKIGGIPEVRKDFITDNGNFILDIKDLKITNPKAMETKLNSIIGVVTNGLFANRGANVLLLGTPNGVKIITN
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: E41LA_DANRE
Sequence: MSCFCSVQEEFYCEVLLLDESKLILTTQQQGIKKSTRGSVVLDYVFSHVNLAETEYFGVRYCDRSHQTFWLDPSKTLAEHKDLIATGPPYTLYFGVKFYAEDPGKLKEEITRYQFFLQVKQDVLQGRLPCAFNISAQLAALAIQSELGDYDPYKHTAGYVSEYRFVPDQKEDLEDSIEQIHKTLLGQVPAEAENNYLAIAKTLEMYGVDLHPVFGEKQAEYFLGLTPVGVVVYKNKTQVGKYFWPRITKVYFKETQFELRVLGRDCNETSFFFDAASKTACKNLWKCCVEHHTFFRMPENESNSLTRKLSKFSSLGSKHRYSGKTAMQIGRESTETLPRADLQVIRTRSKTYPKRSTQPAGRNNGGQAVTKMENTSEGQPKTSALTPVKSPRVKAESASVQQEKPSAPWEEDAPQSGLYNSASERNKSPKFPKAHRRSPSGGSENEPRHRRGQTADDAQANKQHRRRSRSRGNTSSGSESENSNREHRKKRNRSRQSNEMVDSAPQWEVVLRRQKEKTPNDPNQRRSRHRSRSRSPDVQAKEQLWKHIQKELVDPSGLSEEQLKEIPYKKVETQGDPIKIRHSHSPRSFGSTGAPTARTERGLCCPKSTLALIWFLLWL
What is the function of this protein?
Not known, binds calmodulin.
What are the official names of this protein?
Band 4.1-like protein 4, Erythrocyte membrane protein band 4.1-like 4A, Protein Nbl4.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y653_HAEIN
Sequence: MPTISVAMIIKNEAQDLANCLDTVKDWVDEIIILDSGSTDNTKEIALSYGAKFYENSDWQGFGKQRQLAQQYVTSDYVLWLDADERVTPKLQQAILSAVKNDRENTVYEIPRVSEVFGREIRHSGWYPDYVVRLYRTNYAQYNDSLVHEKVEFPAGTKVEKLTGDLEHFTYKSIHHYLVKSAGYAKAWADQRQAKGKKATLWQGISHALGCFVKMYLLKAGFLDGKQGFLLAVLSAHSTFVKYADLWERDQHKH
What are the official names of this protein?
Uncharacterized glycosyltransferase HI_0653.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. WaaE/KdtX subfamily.
Protein: PLSY_CHLCH
Sequence: MLTLLAILVVSYIVGSIPTSLIAGKMLKSIDIRDFGSGNAGGTNAFRVLGWKTGLTVTLIDIIKGVVAAVSVVAFFRHHPIDVFPDINEVALRLLAGMSAVIGHVFTVFAGFRGGKGVSTAAGMLIGIAPVSMLMVIGVFLLTVYISRHVSVASILAAIAFPLIIAIRKYLFELGAGLDYYIKLFNAKFFFHDSLDYHLIIFGLIVAIAIIYTHRANIKRLLAGTENRISFGKH
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM1_CUPPJ
Sequence: MQLLAIGINHTTAPVSLRERVAFPLEQIKPALGALRTHLAGRNGTEAAILSTCNRTEIYCATDILKPGAEGFEHTLRWLSQHHNVPASDLAPHLYSLPQSEAVRHAFRVASGLDSMVLGETQILGQLKDAVRTAGEAGSLGTYLNQLFQRTFAVAKEVRGQTEIGAHSVSMAAAAVRLAQRIFESVSTQRVLFIGAGEMIELCATHFAAQKPRQVVVANRTVERGEKLAEQLAEQGLTTQAIRLQELGERLHEFDIVVSCTASSLPIIGLGAVERAVKRRKHRPIMMVDLAVPRDVEPEVARLDDVFLYTVDDLGAVVREGNALRQAAVAQAEAIIESRVQNFMHWLETRSVVPVIRELQTAGESIRQAELERARRMLARGDDPEAVLEALSGALTRKFLHGPTHALNHMQGEDREALVRLVPGLFRQSSHSER
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: GRAS_STAAN
Sequence: MNNLKWVAYFLKSRMNWIFWILFLNLLMLGISLIDYDFPIDSLFYIVSLNLSLTMIFLILTYFKEVKLYKHFDKDKEIEEIKHKDLAETPFQRHTVDYLYRQISAHKEKVVEQQLQLNMHEQTITEFVHDIKTPVTAMKLLIDQEKNQERKQALLYEWSRINSMLDTQLYITRLESQRKDMYFDYVSLKRMVIDEIQLTRHISQVKGIGFDVDFKVDDYVYTDTKWCRMIIRQILSNALKYSENFNIEIGTELNDQHVSLYIKDYGRGISKKDMPRIFERGFTSTANRNETTSSGMGLYLVNSVKDQLGIHLQVTSTVGKGTTVRLIFPLQNEIVERMSEVTNLSF
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Functions as a sensor protein kinase which phosphorylates GraR through the auxiliary protein GraX.  In turn, GraR up-regulates many genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Sensor protein kinase GraS, Glycopeptide resistance-associated protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.