PharMolix/UniProtQA huggingface dataset:
Protein: TGT_RHILO
Sequence: MAKPFSFKVLATDGRARRGIIDMPRGEIRTPAFMPVGTGGTVKTMYMDQVRGVGADIILGNTYHLMLRPGAERVARLGGLHEFARWPHPILTDSGGFQVMSLSKLRKLTEKGVTFRSHIDGAPYEMSPERSIEIQSLLDSDIQMQLDECTALPAELKEIERAMELSLRWAERCKTAFGDQPGKAMFGIVQGGDNAALRVRSAQALSAMGLKGYAVGGLAVGEPQAVMLEMLDITCPELPADKPRYLMGVGTPDDILKSVARGIDMFDCVMPTRAGRHGLAYTRRGKVNLRNARHADDPRPLDEESDCPAARDYSRAYLHHLVRSQEALGAMLLTWNNLSYYQKLMQDIRAAIETQTFEARGAEITEGWARGDIPVL
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: KCNA4_MOUSE
Sequence: MEVAMVSAESSGCNSHMPYGYAAQARARERERLAHSRAAAAAAVAAATAAVEGTGGSGGGPHHHHQTRGAYSSHDPQGSRGSRRRRRQRTEKKKLHHRQSSFPHCSDLMPSGSEEKILRELSEEEEDEEEEEEEEEEGRFYYSEEDHGDGCSYTDLLPQDDGGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESLCGKEEKCQGKGDESETDKNNCSNAKAVETDV
What is the function of this protein?
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes.  Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient.  The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:8020965).  Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel (By similarity).  Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation.  In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member.  Homotetrameric KCNA4 forms a potassium channel that opens in response to membrane depolarization, followed by rapid spontaneous channel closure (PubMed:8020965).  Likewise, a heterotetrameric channel formed by KCNA1 and KCNA4 shows rapid inactivation (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily A member 4, Voltage-gated potassium channel subunit Kv1.4.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon.
Protein: TRMD_STRTD
Sequence: MKIDILTLFPDMFAPLEHSIVGKAKDKGILEINYHNFRDNAEKARHVDDEPYGGGQGMLLRAQPIFDTFDKLNVTKPRVILLDPAGRTFNQAYAEELAQEEELVFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTIVDATVRLIPEVLGKEASHKDDSFSSGLLEFPQYTRPAEFRGMKVPDVLLSGHHVNIRRWRMEQSLRKTWERRPDLLENYDFTDEERQILEEIKSEGK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATP_SALAR
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVNLLLALENEPVRVNVWIDRHMNPALLNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQRLAGLAQRRGKTLSETIVQLIEDAEHKEKYATTMSTLKQDLQALLGKK
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPA1_ASPFU
Sequence: MANSFPLRVLPTIDPSAGHTFITPSKRIHESEDVSEFLISKAYVDIMTFLLQLNRAMIPVKLADGTVQSWPINTDAVEFSAPVRQLQQLLTKLEELLAEAPPDTGPRRFGNISFRRWYELVESRASELLGECLPSELLQAKSSDPNSVTAEAELKAYFLGSWGSPQRLDYGTGHELSFLAFLAGIWKLNGFPKTTPGVEERAIVLGVIQPYLELVRTIIKRYTLEPAGSHGVWGLDDHSFIPYILGSAQLAPAISETDPTPEEGSLPGAPSPNGVTKAHIVERERLTNMYFSAIGFIYDVKKGPFWEHSPMLYDISGIQAGWGKINKGMIKMYNAEVLSKFPVVQHFPFGSLFSWDRDPNAVPPPTSAHMSTTQSQSRGPAVPSAGQTPPSGTRAPWATATQAAPPAGAGTAAPWAAKRDGCTPGKPPTSLPDTSRLPPGPMAPTRAPWAASSTGQAPGGDPTHVPTKAPWAK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 1, Peptidyl-prolyl cis-trans isomerase PTPA-1, PPIase PTPA-1, Rotamase PTPA-1, Phosphotyrosyl phosphatase activator 1.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YPHB_ECOLI
Sequence: MTIYTLSHGSLKLDVSDQGGVIEGFWRDTTPLLRPGKKSGVATDASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGEWQCVSHSDDSLCLVYEHRSGVYHYRVSQAFHLTADTLTVTLSVTNQGAETLPFGTGWHPYFPLSPQTRIQAQASGYWLEREQWLAGEFCEQLPQELDFNQPAPLPRQWVNNGFAGWNGQARIEQPQEGYAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPGESTTSEMSLRVEWL
What are the official names of this protein?
Uncharacterized protein YphB.
Protein: OBG_MANSM
Sequence: MKFIDEALIRIEAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVYLIADENLNTLIDYRFEKRFAAERGENGRSSNCTGHRGKDITLRVPVGTRAIDNDTKEIIGDLTKNGAKLLVAKGGYHGLGNTRFKSSVNRAPRQKTMGTPGEKRDLQLELMLLADVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVARVDANRSFVVADIPGLIEGASEGAGLGIRFLKHLERCRVLIHLVDIAPIDESDPADNIGIIESELFQYSEKLADKPRWLVFNKIDTISDEEAAKRAKDITERLGWEEDYYLISAATGKNIPQLIRDIMDFIEANPREVEEEEKAAEEVKFKWDDYHNEQLSERGFDDEEDWDDDWSEEDDEGVEFIYKP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOC6_CANLF
Sequence: MAENSEGLGTVPEHERILQEIESTDTACVGPTLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIIQTEDIIRCRIQQRNITTVVENLQYAFPVLEMYSKLKEQMTAKRYYSALKTMEQLENVYFPRVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQQQKTFSVALQKQNNVKFGKNMYINDRIPEERKENELKQGFEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLIVIFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWAGVFRDIFEEDNYSPIPIVNEEEYKAVISKFPFQDPDFEKQSFPKKFPMSQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKLNQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHT
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (By similarity).  Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
What are the official names of this protein?
Exocyst complex component 6, Exocyst complex component Sec15A, SEC15-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SEC15 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody, Midbody ring. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). Colocalizes with CNTRL/centriolin at the midbody ring (By similarity).
Protein: ACP_ALIB4
Sequence: MALLDDVKAVVVEQLDCDPAEVKEDSKFIEDLGADSLDVVELVMALEEKFDIEIPDEDAEKILTVADAIKYIENNA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PI5KA_ARATH
Sequence: MFTREITAKDVKATEKNRIRYSSKHIKHLPPGTITEFEWKDYCPLGFRLIQELEDINHDEYMKSICNDETLRKLSTSKVGNMFLLSKDDRFLIKILRKSEIKVILEMLPGYFRHIHKYRSTLLSKNYGAHSVKPIGGVKTYFVVMSNILQSDVFMNKVYDLKGSSQGRTNKKIKVRDKTILKDIDLDFCFYVDSLARHRLIKQTKLDCELLEDEGIMDYSLMLGLQVKGSCHGSIDELIPVYDSFTSRGSVDSNSSKFMKTASNSPDRSSSTMYSCTPSRNSVDSENSVNIQSVASISPSPAQTNASDSPYESLVSKTNLTNIFQNSSSTNFGMKIPGRARRVGRGESGSVVGKQSREGGEEWYDVILYLGIIDIFQDYGVRKRLEHCYKSIQHSSKTISAVHPKMYSSRFQDFVSQIFLPDEDPSH
What are the official names of this protein?
Phosphatidylinositol 4-phosphate 5-kinase 10, AtPIP5K10, 1-phosphatidylinositol 4-phosphate kinase 10, Diphosphoinositide kinase 10, PtdIns(4)P-5-kinase 10.
Protein: YORL_TTV1K
Sequence: MDVAVVILYSRDDALDLLYRTLHYWWKRSDGLRGQIYVVSNTNVLLPRYAKLIQQKRKGVGGARCDAIESTSEDYIIFSDGHVTPPREISKMLVEPWSSVPINHIILPFGTSGRVAYSLPFMPDERQFLWCSCSKYKEEITTTGEPIVAMSRKYISMSKCYTSYGLDLFQFTLRMPPGQLIGDEGIHFIEAKKLISNRKPNKDEMKDFYDTIYIKRKSEIEEEIKECFCRAL
What are the official names of this protein?
Uncharacterized 26.8 kDa protein.
Protein: RHAB_ECOSM
Sequence: MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIYRFNNGLHSQNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDLQGKRVGLPVAYRDSRTNGLMTQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFTINPNDDRFINPDEMCSEIQAACRETAQPIPESDAELARCIVDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNALLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: EFEU_ECO57
Sequence: MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLLAAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLEQAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLATAVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFDMSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
What is the function of this protein?
Uptake of Fe(2+) ions across the membrane.
What are the official names of this protein?
Ferrous iron permease EfeU, Fe(2+) ion permease EfeU, Ferrous iron uptake protein.
What is the protein family that this protein belongs to?
Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GAGT3_ARATH
Sequence: MRDAIIADPLLAIDHETVAEKKKQSKNLKISLLLLLILLATSGYYSFSDNITTVFLSRQAIDDDHSLSLGTISDVVESENGVVAADDARCSEIGASVLRSGGHAVDAAVAITLCVGVVNPMSSGIGGGSFLIVSSQKDSKAEAFDMRETAPLAASKDMYKNDASAKSLGALSMGVPGEIAGLYEAWKRYGRLPWKPLFEPAIKLARDGFVVYPYLGKAISTKVAMILKDPGMRSVFSRNGQVLKTGETCYNPELAQSLETISEQGPGAFYNGTVGEKLVKDVKKAGGIITMDDLRSYKVRVTDAMSVDVMGYTVHGMPPPSGGTVGFSMVMNILDSYSNLYTASGRELGLHRLIEAMKHMFAARMDLGDPEFVNVTNSMNQMLSKAHAEEIQKRIFDNTTFPPEYYMNRWSQLRDQGTSHFCVVDADRNSVSMTSTVNYRFGAGVLSPSTGIVLNNEMDDFSTPTEITPDMLPPAPTNFIEPNKRPLSSMTPLVITKDGEFVAALGGAGGMHIIPAVLQVFLNCFVLNMKPKEAVESARIYHRLIPNVVSYENFTTINGDHIGVSEDTKMFLAERGHELKELSGGAIVQLIVQSFKEEKEEEMIIEIGRKIGKKSKPLKGLLTAVSDPRKDGKPAAV
What is the function of this protein?
May play a role in protecting plants from some xenobiotic chemicals by degrading vacuolar glutathione conjugates into cysteine conjugates.
What are the official names of this protein?
Glutathione hydrolase 3, Gamma-glutamyltransferase 3, Gamma-glutamyltranspeptidase 3, Gamma-glutamyltranspeptidase 4.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: Y1414_MOOTA
Sequence: MNLLDQQTLINLLHQEADVAIGCTEPVMVALAAAKTRDMLGTLPRLVDISVSSAVWKNARRVGLPGTGEKGLAMAAAMGLLAPVEAGQRLLAALTPVQVEQAKILVREGVVKVGVVAAKEGLYARAVARSNQHEAIVELNGSHKNFSALWLDGRMAGGAGENLNLKLEALLAQDYQSLLKQVLSLSPEELYFLYQGAEDILTFAREIHQGGRNPLSAMASFFRRTESGGESLEVLIRNLTGIAVAERMAGATYPVLTCAGSGNQGILAAVSLLLAGQELRAGPESVTRALAIAHFTNMYLKAYTGKLSPLCGAVTGGAGVAAAICWLLEGSCQQIINAMQIVLGNLCCVICDGAKESCALKISTAAVEAVRAGYMACQGINLEAGTGIVGKKLEDTMELVRKVYQGGLGEIDYYLGKVDYLLSTN
What are the official names of this protein?
UPF0597 protein Moth_1414.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: VNPA_OXYSA
Sequence: SDSKIGDGCFGLPLDHIGSVSGLGCNRPVQNRPKK
What is the function of this protein?
Exhibits vasoactive (PubMed:15652496) and hypotensive activity (By similarity).  Is only weakly active on natriuretic peptide receptor-C (NPR3).
What are the official names of this protein?
Natriuretic peptide TNP-a, Taipan natriuretic peptide, Venom natriuretic peptide OxsSNPa.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOM5_BOVIN
Sequence: MFRIEGLAPKLDPEEMKRKMREDVISSIRNFLIYVALLRVTPFILKKLDSI
What are the official names of this protein?
Mitochondrial import receptor subunit TOM5 homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom5 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: BIOB_ACIAD
Sequence: MTLRNDWTRDEIQALYDQPFLDLVFQAQQVHREHFSANTIQVSTLLSIKTGKCPEDCKYCSQSAHYDSKLEAEKRIAVDKVISEAKAAKDSGSSRFCMGAAWRNPHERDMPYVLEMVREVKALGLETCMTLGMLNQSQAERLSDAGLDYYNHNLDTSREYYNNIISTRTFDDRLNTLDHVRSAGMKVCSGGIVGLGEQKQDRIGLLHELATLPIHPESVPINMLVPIEGTPLADVEKLDVTEWIRTIAVARIIMPYSYIRLSAGRESLSDSDQALAFMAGANSLFSGDKLLTTPNAGEGKDQVLFAKLGLVAEKPKVSVRAMAVDAMSA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: QUEC_SALTI
Sequence: MKRAVVVFSGGQDSTTCLAQARHQYDEVHCVTFDYGQRHRAEIDVARALALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPNADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVNLGMAKDIRFETPLMWIDKAETWALADYWGQLDLVREETLTCYNGIKGDGCGHCAACNLRANGLNHYLSNKAAVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ATPA_NOSP7
Sequence: MSISIRPDEISSIIQQQIEQYDQEVKVANVGTVLQVGDGIARIYGLEKAMAGELLEFEDGTIGIAQNLEEDNVGAVLMGEGLEIQEGSSVTATGRIAQIPVGEALIGRVVDALGRPIDGKGDIKSSESRLIESPAPGIIARRSVHEPMQTGITAIDSMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKEEDVICVYVAIGQKASTVANVVQTLQEKGAMDYTIVVAASASEPATLQYLAPYTGATIAEYFMYKGKATLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYIHSRLLERAAKLSDELGKGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGIRPAVNPGISVSRVGSAAQTKAMKKVAGKIKLELAQFDDLQAFAQFASDLDKATQDQLARGQRLRELLKQPQNSPLSVYEQVAILYAGINGYLDDVPVDKVTSFTQGLREYLKTGKTQYAEGVRTSKALGDAEEAALKEALTEYKKTFKAAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: SDHA_PARDE
Sequence: MAAYKYETHEYDVVVVGAGGAGLRATLGMAEQGLRTACVTKVFPTRSHTVAAQGGIAASLSNMGPDNWQWHMYDTVKGSDWLGDTDAMEYLAREAPKAVYELEHYGVPFSRTEEGKIYQRPFGGHTTEFGEGPPVQRTCAAADRTGHAILHTLYGQSLKEKAEFFIEYFALDLIITDGACTGVVCWKLDDGTIHVFNAKMVVLATGGYGRAYFSATSAHTCTGDGGGMVARAGLPLQDMEFVQFHPTGIYGSGCLITEGARGEGGYLTNSEGERFMERYAPTYKDLASRDVVSRCITIEIREGRGVGPHKDHMHLNLMHLPPESLAERLPGISESAKIFAGVDVTREPIPILPTVHYNMGGIPTNYWGEVLNPTQDNPDQVFPGLMAVGEAGCASVHGANRLGSNSLIDLVVFGRAAAIRAGQVIDREAQIPTTNKEQVDKALDRFDRIRNADGSVSTADLRLEMQRTMQADAAVFRTDKTLAEGVDKMRVIAGKLSDLKVTDRSLIWNSDLMETLELTNLMPNALATIVAAEARKESRGAHAHEDYPERDDANWRKHSLAWIEGNDVKLAYRPVHLEPLTRQDEGGIDLKKIAPKARVY
What are the official names of this protein?
Succinate dehydrogenase flavoprotein subunit.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CHEB1_DECAR
Sequence: MPIKTRVLVVDDSALMRGLLSQMINLAPDMEVVGAAPDAQSAREMIKVLNPDVLTLDVQMPKMDGLEFLERLMRLRPMPVVMVSSFTEAGSDTTLKALELGAIDFIGKPRADGGRSVENYAEELVEKIRAAKAARLRRAMTGNSVRAATPASASPKSGLGASGKIIFVGASTGGTEAIKDFLLGIPADCPPILIVQHMPEAFTASFARRLDSLCAPRIIEAKGNEKVEPGTIYVAPGHSHLLIRRGTAGFLTELAATPPVNRHRPAVDVLFDSAATLVGRKAIGVILTGMGKDGAQGLLRMRQAGARTFGQDESSCVVYGMPREAFLIGAVEEQCSLDEMARRVLGAVSA
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_CLOK5
Sequence: MLERLNFIENKYEELSIKISDPTIIADQKKWQKLCKEHAELEEIVMKYREYKEALQDLEDNKEMLREETDKDMREMEQEEIKRLGDIIEKREDELKILLLPKDPNDDKNVFVEIRGGAGGEEAALFAANLTRMYTRYAEIKGWKVETISLSATDIGGFKEIVFMVKGKDAYSRLKYESGTHRVQRVPDTESSGRIHTSTATVAVLPEVDDVDIVVNQNDIRIDVFRASGHGGQCVNTTDSAVRITHLPTGLVVSCQDEKSQLKNKEKAMKVLKSRLYEKAQEERNASIAEDRKNQVGTGDRSERIRTYNYPQGRVTDHRIGMTLYKLDSFLNGDIDEIIDALITEDQAQKMKSIGSR
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAS1_RABIT
Sequence: MRSEMLTALLTLAVLLQVAGSLKIAAFNIRSFGETKMSNATLTSYIVRILQRYDIALIQEVRDSHLTAVGKLLDKLNEKAADTYRFVASEPLGRRTYKERYLFVYRPDQVSVLDSYYYDDGCEPCGTDTFSREPAVVRFSSPSTKVREFAIVPLHSAPEDAVAEIDALYDVYLDVQKKWGLQDVMLMGDFNADYSYVTSSQWSSIRLRTNPAFKWLIPDTADTTATSTNCAYDRIVVAGPLLQDAVVPNSAAPFNFQAAYGLSNQLAQAISDHYPVEVTLA
What is the function of this protein?
Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (PubMed:9230129).  Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity).  Among other functions, seems to be involved in cell death by apoptosis.  Binds specifically to G-actin and blocks actin polymerization (PubMed:9230129).  Preferentially attacks double-stranded DNA and produces oligonucleotides with 5'-phospho and 3'-hydroxy termini (PubMed:9230129).  Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity).  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity).  Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation (By similarity).
What are the official names of this protein?
Deoxyribonuclease-1, Deoxyribonuclease I, DNase I.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Secreted. Zymogen granule. Nucleus envelope. Note=Secretory protein, stored in zymogen granules and found in the nuclear envelope.
Protein: MNMA_FERNB
Sequence: MSAKVGVLLSGGVDSAVALYLLIEKGYEVTAYHMKTVRDELYITKQIKHKVCCSPSDTHDAQLIAKKFGVPFKIIHVEDVFKEKIIDYFISENLAGKTPNPCFFCNDYIKFGFVMDVALSDGMDFVASGHYARILNGKLYRALDKEKDQSYFLASIKKEKLSKILLPNGEYSKETIRDIAERAGIHVAKKIDSQDLCFLPDNDFKSFFEERGVKIEPGNIITSEGKIIGKHEGLPFYTIGQRKLGVAAGQKLYVKAKNVEGNFIVVSPLDEVYQNEMRVKNLNIYVDLPDEFLATVKIRKKFKEVPCRVEYLKDELKVQFLEPVFAVTPGQIAVFYNEDEVLCSGVIE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_NOCFA
Sequence: MSESPHDHAGDPVRLSAWVHGHVQGVGFRWWTRSRALESGLTGYARNAPDGRVHVIAEGPRERCERLLELLRSGTTPGRVSLVVESWEPARGDLTGFEER
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.