PharMolix/UniProtQA huggingface dataset:
Protein: NUOB_SHIBS
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLNDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y589_HAEIN
Sequence: MMSYDAETGIAKVKCQSQSTCGACSARETCGTESLSELNGKRGEHIFTLETITPLRTDQMVEIGLEEKSMLFSALLMYIVQLFTLLVATLLSSYISENELIRAILIFMLTALSFVMVKRYTRKLGQQTEFQSVLLRVLF
What are the official names of this protein?
Uncharacterized protein HI_0589.
What is the protein family that this protein belongs to?
Belongs to the RseC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDV1_ASPFU
Sequence: MATQRRDESPSGLSDIVEPDGLLGIGLTSRHIEAFGRKVTSTAGHLMGPITDSSNGSHYHTAMADIHRELRRPTTQRKVFSLTQTSPTDLVRSKLSTSEIQSRALSSVPDELLANIPEDSSSYSLFEGFKATQDDHEFRKAHRRRSSKGKKLLKDGEAAGALPSAPTDLKKERDLLSRRLDLMGVRKNMCSSEIHEIDNKIANLHNIRKIVLDRLAGLEMEEAELEHQLTEIDNKLEDIQEEAPKTPLTAATPKSSSVNDDSVVSEDAALDASFMSESIYQKLPSHSPRSLKQRSIRKRSMPILHEHFAPGSQIKEMQAHTDMVTAIDFDYPFGTMVSAALDDTVRVWDLNTGRCTGFLEGHNASVRCLQVEDNIVATGSMDASVKLWDLSRARTVTRDNRLNKPSEGEGEDDNASDAFSLFSATTLEDCYVFSLDAHVDEVTALHFRGNTLISGSADKTLRQWDLVKGRCVQTLDVLWAAAQASTLAADTQWRPSGRLPDASADFVGALQCFDAALACGTADGMVRLWDLRSGQVHRSLVGHTGPITCLQFDEVHLVTGSQDRSIRIWDLRMGSIFDAYAYDKPITSMMFDTKRIVAAAGENVVKVYDKADGHHWDCGAGVGADESGPAPATVERVRLKDGYLLEGRKDGTVAAWTC
What is the function of this protein?
Involved in mitochondrial fission.  Acts as an adapter protein required to form mitochondrial fission complexes.  Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).
What are the official names of this protein?
Mitochondrial division protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MDV1/CAF4 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YELL_DROER
Sequence: MFQDKGWVLVTLIALVTPSWAAYKLQERYSWNQLDFAFPNARLKEQALASGDYIPQNALPVGVEHFGNRLFVTVPRWRDGIPATLTYINMDRSLTGSPELIPYPDWRSNTAGDCANSITTAYRIKVDECGRLWVLDTGTVGIGNTTTNPCPYAVNVYDLTTDTRIRRYVLPAVDTNPNTFIANIAVDIGKNCDDAYAYFADELGYGLIAYSWEQDKSWRFSAHSYFFPDPLRGDFNVAGINFQWGEEGIFGMSLSPIRSDGYRTLYFSPLASHRQFAVSTRILRDETRTEDSYHDFVALDERGPNSHTTSRVMSDDGIELFNLIDQNAVGCWHSSMPYSPQFHGIVDRDDVGLVFPADVKIDENKNVWVLSDRMPVFLLSDLDYSDTNFRIYTAPLATLIENTVCDLRNNAYGPPNTVSIPKQAVLPVGPPLYTKQYRPVLPQKPQTSWASSPPPPSRTYLPANSGNVVSSISVSTNTVGPAGVEVPKAYIFNQHNGINYETSGPHLFPTLQPAQSGRQDGGLKTYVNARQSGWWHHQHQG
What is the function of this protein?
Controls the pigmentation pattern of the adult cuticle and larval mouth parts.
What are the official names of this protein?
Protein yellow.
What is the protein family that this protein belongs to?
Belongs to the major royal jelly protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBL_CITSI
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYH_STRM5
Sequence: MIKPRTPPGTLELLPREQIAFQRMLDVIRRNYERFGFLPVETPVFELSDVLLTKSGGETERQVYFVQSTGALANAAESGDRSLPEMALRFDLTVPLARYVAEHEHELTFPFRRYQMQRVYRGERAQRGRFREFYQCDIDVIGKDSLSVRYDAEVLAVIHAVFSELRIGDFSIQLNNRNLLRGYFESLGVAEGERQLAVLREVDKLDKRGADYVRETLVGEGFGIPAEQVEKILAFVAVRSKGHDDALAQLAALEAAAESSETLRAGVAELREVLQLVQALGVPETAYCLNFSIARGLDYYTGTVYETTLTDHPQIGSICSGGRYEDLASHYSKSKLPGVGISIGLSRLFWQLREAGLIDGIEASSVQALVALMDEQGMPQSLDIARRLRAGGINTEVQMEPKKIGKQFQYAAKAGIRFVVLAGEDELARGVVAVKDLLREQQFEVSRDELASTLLVELEQSRAMV
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDP_STAAN
Sequence: MRMIDIIEKKRDGHTLTTEEINFFIDGYVKGDIPDYQASSLAMAIYFQDMNDDERAALTMAMVNSGDMIDLSDIKGVKVDKHSTGGVGDTTTLVLAPLVAAVDVPVAKMSGRGLGHTGGTIDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPADKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALAHAMVRIGNNVGRNTMAIISDMNQPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLGSQMVVLANKAETLEEARALLIEAINSGAALEKFKTFIKNQGGDETVIDHPERLPQAQYQIEYKAKKSGYVTELVSNDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGESLLTIHSNRQDVDDVVKKLDSSITIADHVVSPTLIHKIITE
What is the function of this protein?
Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
What are the official names of this protein?
Pyrimidine-nucleoside phosphorylase, PYNP, Py-NPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: NLTP2_TOBAC
Sequence: MEMVGKIACFVVLCMVVVAPHAEALSCGQVQSGLAPCLPYLQGRGPLGSCCGGVKGLLGAAKSLSDRKTACTCLKSAANAIKGIDMGKAAGLPGACGVNIPYKISPSTDCSKVQ
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 2, LTP 2.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: CH60_BACAA
Sequence: MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVVAAVEELKTISKPIEGKSSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGEVITEELGRDLKSATVESLGRAGKVVVTKENTTVVEGVGSTEQIEARIGQIRAQLEETTSEFDREKLQERLAKLVGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNVYTKVASIVAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLETGIVDPAKVTRSALQNAASVAAMFLTTEAVVADKPEPNAPAMPDMGGMGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNW_SALCH
Sequence: MTSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNIGVVEQIRQQLTALATASEGYTSVLLQGSGSYAVEAVLGSALGPQDKVLIVSNGAYGARMVEMAGLMGIAHHAYDCGEVARPDVQAIDAILNADPTISHIAMVHSETTTGMLNPIDEVGALAQRYDKTYIVDAMSSFGGIPMDIAALHIDYLISSANKCIQGVPGFAFVIAREQKLAACKGHSRSLSLDLYAQWRCMEDNHGKWRFTSPTHTVLAFAQALKELAEEGGVAARHQRYQQNQRSLVAGMRALGFNTLLDDELHSPIITAFYSPEDPQYRFSEFYRRLKEQGFVIYPGKVSQSDCFRIGNIGEVYAADITALLTAIRTAMYWTK
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: BANP_XENTR
Sequence: MMSGQELAEVVQIAVEDLHPGHHPVVLENHEVTEEDLSPTLKRQRIEINCQDPSIKSFLFSINQTICLRLDSIESKLQVLEATCKSLEEKLDLIMNKQQNPVQVPVVAGSPLGATQTWNKVRCVVPQTTVILNSERQTPGVTKLEGREESINSSTETLENMLNSAVPGRRHNTIVVKVPAPEDSHNDDDNDSGSEASDTLSNCGNSGNPNMGNNVTLITLNSEEDYPNGTWLGDEHNPEMRVRSPITAADMLHISTNCRTAEKMALTLLDYLFHREIQAISNLSGQGKHGKKQLDPLMIYGIRCHLFHKFRITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSTTEGVQNTVSSSSDLQQTSPQALHYALANAQQVQIHQIGEDGQVQVGHLHIAQVPQGEQVQITQDSEGNLQIHQVHVGQDGQVLQGAQLIAVASADPTAGVVDGSPLQANDIQVQYVQLAPVAEPSATAQAVEPLQSALQPEMHIEHGSIQIQ
What is the function of this protein?
DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels.  Promotes activation, which causes cell cycle arrest (By similarity).
What are the official names of this protein?
Protein BANP.
What is the protein family that this protein belongs to?
Belongs to the BANP/SMAR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_ACTPJ
Sequence: MNLNATLIGQLIAFALFVAFCMKFVWPPLIKAIEERQANIANALASAEKAKQEQADSKAAADQEILKAKEEAQKIIDLATKRRNEILESVQAEAEIERQRIIEQGHAEVESERKRVQEELRQKVAALAVAGAEKIVGRSVDQAANNDIIDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MUTL_VIBCM
Sequence: MTIRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNGSGIDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEAWSAYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIALSRFDVSFTLRHNGKIVRQYRAATTLPQQEKRLAAVCGNPFVQHMLRIELEHQGLKLHGWITTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIELDPHQVDVNVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINEGAFHLPHCAEEVNPPVVPMIDTTQQERVWQAVQNTPDYPRKAPRDNDRDESDNPQVRERAVSNPWVASPKTASTGKERYGSASVSKKEAAVYQTLMQTPDLSDEEPSTASTIVSSIEAVKANIAIEKLGKAIQVVAGQYLLMSSPQGCVLISLYQAQQLKLRGLLNAQHGALKAQPLLVPLALKLNESEWQVAQRHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLSYAASCSESQALSHQALADWLTQRIVVEKRDYTLAEAIGLIAELEQLWQGNLPLQDPHFITLVDFSASITALHS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: LACR_LACHE
Sequence: MRTIKEIALESGYSPATVSRLLNNDPNLSITADTKNKILEIANKLGYWEDHQEKKIKPTIALLYRVNHNEQLQDEYFTSLKQALVSTVERDALKMKTFYDIEDLIKNASLFQGFIGVGAEPIENAQLVKLHKVLPNGVFVDTNPAPELFDSIRPNLPFTVKNAIDLFIKNGINKIGFIGGVGPKHDHIQENDLRSITFVEYMKTRGMDTKWTCVEGPVSVENGYKLGKMVLAKYKNDLPEAFLIASDTLAVGVLQAFNEENVNVPKDTKILSINNSNVVKYVSPPLSSFNINQQEMIDMALDTLTHLIIRPDRPNIDIRMNTNLVVRKSFVPQEK
What is the function of this protein?
Negatively regulates the transcription of the lactose utilization genes lacL and lacM.
What are the official names of this protein?
HTH-type transcriptional regulator LacR, Lactose operon repressor.
Protein: RS19_BRUA2
Sequence: MARSVWKGPFVDGYLLKKAEKVREGGRNEVIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSEEMVGHKFGEFAPTRTYYGHGADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: APD1_YEAST
Sequence: MAFLNIFKQKRGDEASQLSAKGREEISQSIKICKSDDAANEHSCSGDCKTEIEEGEQAFAKLKIEHETPLLNSSKTPKIHFVVPTSQIDWQHDACLEDPKSVQYKISQWCDKNSAKFSNVGTGKTLNCAVSSLPKDIMDIDVMRGTKNNVLILPYFIWLNDLRSDDVEATLDGLVPDLLDENISREKLLETRPNVAVARERAFVFICSHTTRDKRCGITAPYLKKVFDSKLQEHGLYRDNSDYRAEGVKIAFVNHVGGHKFAANVQIYLRNPNTLIWLGRVTPTIVPSIVEHLIVPEEPTLPFPEKVRCIKKYQSW
What is the function of this protein?
Required for normal localization of actin patches.  Involved in tolerance to sodium ions and hydrogen peroxide.
What are the official names of this protein?
Actin patches distal protein 1.
What is the protein family that this protein belongs to?
Belongs to the APD1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DIAA_ECO81
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: CDPAS_SULTO
Sequence: MPIIYYVIFAILYYLPALVANGSAPFVKNGTPIDFRKNFVDGRRLLGDGKTFEGLLVAVTFGTTVGIILAKFLGIYWIYVSFIESLLAMLGDMVGAFIKRRLGLARGARAIGLDQLDFILGATLALIISKISLNIYEFLSIVVIAFVLHILTNNVAYRLKIKSVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRUA_BURM1
Sequence: MRIALGIQYDGAAFCGWQAQPHGNTVQDALERALAEFARVPLHTTVAGRTDTGVHGLGQVVHFDTELDRADFSWVRGTNAFLPPTVAVQWAKSMPDAFHARFSAFERTYYYALYVHPVRSPMLDGRAGWIHTPLDDDAMRAAAAHLLGEHDFSAFRSSECQSKTPVKHLYEIDIRRVGHFLHFRFRANAFLHHMVRNLMGCLVAVGRGRYPADWVADVLAGRDRNRAAPTFMADGLYLAHVGYPAEFAVPPAQLGSVPWSSVWADLDPQP
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MOXJ_PARDE
Sequence: MLIDFRQVCGAGAAALALASPALADTTNLRVCASTKDAPFSDAQGAGFENKIAQVLADEMGATLDLVMLEKDAIYLVRDGIEKDLCDVLVGVDAGDERLLTTRPYYRSGYAFVTRQDRNFEGDKWQDVDQEGFDTFSYRLHSPAETILKYTGRYEYNLIYQASLTNFEDRRNKYTQVEASRVITEVADGGADLAIVFAPEAARYVRDSREPLRMTLITNEIERSDGVIIPLQYSQSVGVSKTHPELLGPIEQALQSGKARIDAILTEEGIPLLPSS
What is the function of this protein?
May be involved in the assemblage of active methanol dehydrogenase and/or its cofactor PQQ in the periplasm.
What are the official names of this protein?
Protein MoxJ.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL1_CAMLR
Sequence: MSKNTKRFTELLKKIDSNKNYLMDEAISTVKTLASAKFDETVEIALKLNVDPRHADQMVRGSVVLPCGTGKKVRVAVIAKDAKADEAKNAGADIVGSDDLVEEIQKGNMNFDVLIATPNLMGLVGKVGRILGPKGLMPNPKTGTVTMDVAQAVNNAKNGQVNFRVDKQGNIHAGLGKVSFTQEQLKENMSAFVKAINKHKPAAAKGRYIKNASLSLTMSPSLSLDTQELLDTK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: DCUP_ALIF1
Sequence: MTELKNDRYLRALLKQPVDYTPVWMMRQAGRYLPEYKATRAEAGDFMSLCKNAELASEVTLQPLRRFPLDAAILFSDILTIPDAMGLGLYFETGEGPKFERPITCKADVDKIGLPDPEGELQYVMNAVRQIRKDLKGEVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKMMYAEPATLHLLLDKLADSVIEYLNAQIKAGAQSVMVFDTWGGVLTPRDYNEFSLRYMHKIVDGLIRENEGRRVPVTLFTKNGGMWLESIAATGCDAVGLDWTINIADAKARIGDKVALQGNMDPSILYAQPERIRQEVGTILEGFGDAGTGHVFNLGHGIHLDVPPENAGVFVDAVHDLSKPYHK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_XYLFT
Sequence: MLHPALALVPGEPAGVGPELCVRLVQQPRQDCRLVAFADPATLQAAAAALDLPLRLLPPEALPERPGDLPIQAHCHVHPTRFGHPDPANAPAVIAALCEAASHCVHGVLHGIVTGPVHKAVINQSGIHYTGTTELLAAQAECDVVMMLANPHLRVALVTTHLPLRDVPDAITAALLERCLRIVNTAMCGDFGIATPRIAVLGLNPHAGEEGYLGREELDVVIPVLQRLRAEGMVLLGPLSADTAFLPTKLIGYDAVVAMYHDQGLPVLKHSGFEQAVNITLGLPYPRVAVDHGTALDLAGRGVADPSSLFAATALCARLAASRALLSVRS
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_MANSE
Sequence: MKLNVSFPATGCQKLFEVVDEHKLRIFYEKRMGAEVEADLLGDEWKGYVLRVAGGNDKQGFPMKQGVLTNSRVRLLMSKGHSCYRPRRDGERKRKSVRGCIVDANLSVLALVIVRKGEQEIPGLTDGNVPRRLGPKRASKIRKLFNLSKEDDVRRYVVKALLPAKEGKENAKPRYKAPKIQRLVTPVVLQRRRHRLALKKKRLAKRKSAEADYAKLLAQRKKESKVRRQEEIKRRRSASMRDSKSSNQSAPQK
What is the function of this protein?
Component of the 40S small ribosomal subunit (By similarity).  Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (By similarity).
What are the official names of this protein?
40S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: PAHX_CAEEL
Sequence: MLGKGVVDYTREGSILSAEQRRFYEKNGYLLIRNCVPQYELNRFRQRFQDICEKKVKAPENMTVMKDISIAKSEFKDGEKAITKIQDFADDPVLFEYCKYPGVVDVVKDLIGNPKSNLMAMHTMLINKPPDNGKLTSRHPMHQDLQYFPFRPADFICCAWTAMEKITRANGCLVVVPGTHKGVLLPHEYPKWEGGVNKAYHGIQDYDTSTPRIHVEMEPGDTVFFHPILIHGSGANRTEGFRKAISCHYANDDLCRYVNVEGTTQETLAEEIIEIAKKRLTRYGLDPNTVTLDFADIWRVRAREVNGRRSNL
What is the function of this protein?
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
What are the official names of this protein?
Probable phytanoyl-CoA dioxygenase, Phytanic acid oxidase, Phytanoyl-CoA alpha-hydroxylase, PhyH.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: Y106_AQUAE
Sequence: MVAFFSPLREPLSLFRISTSPRSFRKVPHLLLLRQTSPCSSQSFSIIFISLSSSNSREGIVFTLSFLIFESNTLLFSSRKSFTLSAFPSGRTVKYTLALLPSLLSSTLVMLTTPKSVGAFSTTKLAIISFICSPSLSFFLLILYLLQHIFVLFKLFAVEYVRYELVYFLFLEYRTRQQSSRVLVVLYLPEHEKFRKSVLNLSVSVTILAVLQGILFYEKVIFTEFYDVEYSPPSSSYEF
What are the official names of this protein?
Uncharacterized protein aq_106.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: T2R50_HUMAN
Sequence: MITFLYIFFSILIMVLFVLGNFANGFIALVNFIDWVKRKKISSADQILTALAVSRIGLLWALLLNWYLTVLNPAFYSVELRITSYNAWVVTNHFSMWLAANLSIFYLLKIANFSNLLFLHLKRRVRSVILVILLGTLIFLVCHLLVANMDESMWAEEYEGNMTGKMKLRNTVHLSYLTVTTLWSFIPFTLSLISFLMLICSLCKHLKKMQLHGEGSQDLSTKVHIKALQTLISFLLLCAIFFLFLIVSVWSPRRLRNDPVVMVSKAVGNIYLAFDSFILIWRTKKLKHTFLLILCQIRC
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 50, T2R50, Taste receptor type 2 member 51, T2R51.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GYRB_ACIJU
Sequence: DNSYKVSGGLHGVGVSVVNALSKKLHLTIQRAGQIHEQEYCHGDPQYPLKVVGETDKTGTTVRFWPSELTFSQTIFSVDILARRLRELSFLNAGVRIVLRDERVNLENVYDYEGGLSEFVKYINEGKTHLNEIFHFTTDADNGIGVEVALQWNDSYQENVRCFTNNIPQKDGGTHLAGFRAALTRGLNSYMENENLLKKEKVAVSGDDAREGLTAIISVKVPDPKFSSQTKEKLVSSEVKPAVEQAMNKEFSAYLLENPQAAKSIAGKIIDAARARDAARRAREMTRRKSALDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKQGRNRKMQAILPLKGKILNVERARFDKMISSQEVGTLITALGCGIGREEYNPDKLRYHKII
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL332_LIMF3
Sequence: MRVNITLECTSCHERTYLTSKNRRNNPDRLELNKYCPREHKVVLHRETK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CYB_PROSA
Sequence: MTNIRKTHPLLKIVNHSLIDLPAPSNISAWWNFGSLLGLCLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNHGWIIRYLHANRSSMFFICLYMHVGRGIYYGSYTYTETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGIPSNSDKIPFHPYYTIKDALGFLMLISLLLLLALFTPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIIPLLHTSKQRSMMFRPLSQALFWILVADLVTLTWIGGQPVEHPFITIGQAASVLYFTLILILMPLASLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.