PharMolix/UniProtQA huggingface dataset:
Protein: HTR2_NATPH
Sequence: MSLNVSRLLLPSRVRHSYTGKMGAVFIFVGALTVLFGAIAYGEVTAAAATGDAAAVQEAAVSAILGLIILLGINLGLVAATLGGDTAASLSTLAAKASRMGDGDLDVELETRREDEIGDLYAAFDEMRQSVRTSLEDAKNAREDAEQAQKRAEEINTELQAEAERFGEVMDRCADGDFTQRLDAETDNEAMQSIEGSFNEMMDGIEALVGRIERFADAVSEDAEAVRANAESVMEASEDVNRAVQNISDAAGDQTETVQQIALEMDDVSATTEEVAASADDIAKTARQAAETGEAGRETAETAITEMNEVESRTEQAVASMEELNEDVREIGEVSEMIADIAEQTNILALNASIEAARADGNSEGFAVVADEVKALAEETKAATEEIDDLIGTVQDRTQTTVDDIRETSDQVSEGVETVEDTVDALERIVDSVERTNDGIQEINQSTDAQADAAQKATTMVEDMAATSEQTASDAETAAETTETQAESVKEVFDLIDGLSEQADSLSETLSRTDTEEASAADLDDQPTLAAGDD
What is the function of this protein?
Transduces signals from the phototaxis receptor sensory rhodopsin II (SR-II) to the flagellar motor.  Responds to light changes through the variation of the level of methylation.  Also acts as a chemotransducer.
What are the official names of this protein?
Sensory rhodopsin II transducer, HTR-II, Methyl-accepting phototaxis protein II, MPP-II.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AMPA_CLOTE
Sequence: MKFHIGKDGEVKIILVYKNAEKVEEANDLYSYLKEKELFKGDLGEVYSHISHSEDKFILLGIGEKEKTTANSLRKAFFNAGKELMKFKVTSIKISIPMFKNLKYESIVQSITEGLLQSEYSFEKYLTKKKISPSIKNVYLDILEEKKEETINTINESKNLIEGIFLARNLVNEPAIYMTPTVLANNAKNQLESLGVEVKIYGKEKIKELGMEAFLAVSKGSFEESQLIVMNYKGNSNSDKKLALVGKGLTYDSGGYSIKPTSSMINMHSDMAGSASVIGAMKAIAMSKLEVNVVAIVAACENMISGGAYKPGDIISSMSGKTIEILNTDAEGRLTLADALWYAVDVVKADKIIDIATLTGACVTALGSINTGAITNNSYLMDNVKKASECAGEPVWEFPNNDEYKELIKGTFGDLKNSSGREAGAITAGMFLQEFVGNTPWVHLDVAGTAYLSSKNGYLQKGATGVPVKTLYYLAKGFKNK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C82A1_PEA
Sequence: FVLNYLNTTTIAFISLISLLFFLFRFSKVSHTKEPPIISGSWPLLGHLPLMRNTQTPHKTLGALVDKYGPIFTIKLGATNALVLSNWELAKECFTKNDIVVSSRPKPVAVELMSYNQAFIGWAPYGAYWRQLRKIVTLEILSNRRIELLSHIRVSEVQTSIKELVNVWSNQISSQYGLLDDTKSSSTNDEPSTTDYVSVELKKWFAQLTLNMVLRMVVGKRCFGDVDVENKEEAKRFLENIRDFMRLIGTFTVGDGVPFLKWLDLGGHEKEMKKCAKKFDVMLNEWLEEHREKKGLGSEDKVVGERDFMDAMLLVLKDKPIEGFDVDTIIKATTLELILGGSDTTAGTLTWAMCLLLKHPHVLEKLKEELNTYIGKERCVNESDINKLVYLHAIIKETLRLYPPAPFSSPREFTEDCTIGGYHIKKGTRLMPNLWKIHRDPSVWPDPLEFKPERFLSTHKDVDVRGQNFELLPFGSGRRMCAGMSLGLHMVHYILANFLHSFEILNPSPESIDVTEVLEFVTTKATPLEVLVKPCLSFKCYESM
What are the official names of this protein?
Cytochrome P450 82A1, CYPLXXXII.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: MDTC_ECOL6
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGAVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRGERSETAQQIIDRLRKKLAKEPGANLFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQEDNGAEMNLIYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQAVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATA_OCEIH
Sequence: MSLFDYTIKELEEKLHNKEITVEDLVKESYQRIHEVDQEVHAFLTLDEEKALEKARELDQLEDKTGILFGMPGGIKDNIVTKGLRTTCASQFLDNFNDPLYDATVVQKLQKENMVAVGKLNMDEFAMGSSNENSGYEPTRNPWNTEHVPGGSSGGSAAAVAAGEVLFTLGSDTGGSIRQPAAFCGVVGMKPTYGRVSRFGLVAFASSLDQIGPVTRTVEDNARVLEVIAGHDQMDTTSANVEVPSYTEALKQDVKGLKIAVPKEYLAEGVSKEVKDAILEALKVYESMGATWEEVSLPHSKYALATYYLLSSSEASANLARFDGVRYGVRSENADNMIDMFKKSRSEGFGEEVKRRIMLGTFALSSGYYDAYYKKAQKVRTLIKNDFDKILEEYDVIVGPTTPTPAFKVGEKTSDPLTMYANDILTIPVNLAGVPGISIPCGFSTEGLPIGLQIIGNYFDESTVYRTAYAYEQATEHHKKRPQLGGAK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: HOA_LEPCP
Sequence: MTVQGKKITVHDMTLRDGMHPKRHLMTLEQMKNIATGLDEAGVPLIEVTHGDGLGGSSVNYGFPAHSDEEYLGAVIPLMKQAKISALLLPGIGTVEHLHMAKDLGVHTIRVATHCTEADVSEQHITAARKLDMDTVGFLMMAHMASPEKLITQAKLMEGYGANCIYVTDSAGYMLPGDVKLRLEAVRAALRPETELGFHGHHNLAMGVANSVAAVEAGANRIDAAAAGLGAGAGNTPMEVFIAVCDRMGIETGVDVFKIQDVAEDRVVPIMDHIIRVDRDSLTLGYAGVYSSFLLFAKRAEKKYGVSARDILVEMGRRKMVGGQEDMIEDTAITMARERAGCAAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: DNAJ_BURMA
Sequence: MAKRDYYEVLGVAKNASDDEIKKAYRKLAMKYHPDRNPDSKDAEEHFKEAKEAYEMLSDGQKRAAYDQYGHAGVDPNVGAAGAQGFGGFADAFGDIFGDIFGQAAGGGRARGGPQVYRGADLRYSMEITLEQAAHGYDTQIRVPSWAACGVCHGSGAKPGTKPETCPTCHGQGTVRMSQGFFSIQQTCPKCHGTGTYIPEPCAHCHGSGKVKETKTLEVKIPAGIDDGMRIRSAGNGEPGINGGPSGDLYVEIHIKPHAVFERDGDDLHCQMPIPFTTAALGGEIEVPTLAGRASFTVPEGTQSGKTFRLRGKGIKGLHSSIAGDLYVHVQVETPVKLTDQQRDLLKQFEKSLAEGGPRHSPQSKSWFDRVKSFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHE2_STAA9
Sequence: MNQIVLNIIIAFLWVLFQDEDHFKFSTFFSGYLIGLIVIYILHRFFSDDFYVRKIWVAIKFLGVYLYQLITSSISTINYILFKTKDMNPGLLSYETRLTSDWAITFLTILIIITPGSTVIRISQDSKKFFIHSIDVSEKEKDSLLRSIKHYEDLILEVSR
What are the official names of this protein?
Putative antiporter subunit mnhE2, Mrp complex subunit E2, Putative NADH-ubiquinone oxidoreductase subunit mnhE2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIS13_SCHPO
Sequence: MKRKPEEQEGFVFVRKGKEKAGSKRRKSSVEDDPDTSQTDGLVELPVSDTPIVKRNKELRKGKGRRSSLDQRGKRASSIGTGFEALPHADVPSHEYYRHISKDLSEPLRIKQLLLWASSKALEEQRKKYGETEEASEAAIARSIVQEVLNELLANKVSVSWYQRPPDAVIPNKPHPQNLKNAQLVDELSAKLTQLHNEEAAWRAVAANSVSSDKSILSFKKAVESIDSKQDLDKQDSPLPPDDAPELPNISKLKPKFHTLLDMLAENIHTLHSLTNAGPEVRSSYGRLAAQDFIAHRKSLLSFSKYVDTMNLLRLLSEASYKSSSNESV
What is the function of this protein?
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle.  Required for correct segregation of chromosomes and for maintaining the inner centromere structure.
What are the official names of this protein?
Kinetochore protein mis13, NMS complex subunit mis13.
What are the subcellular locations of this protein?
Nucleus.
Protein: LUXB2_PHOLU
Sequence: MKFGLFFLNFINSTTIQEQSIARMQEITEYVDKLNFEQILVCENHFSDNGVVGAPLTVSGFLLGLTEKIKIGSLNHVITTHHPVRIAEEACLLDQLSEGRFILGFSDCERKDEMPFFNRPEQYQQQLFEECYDIINDALTTGYCNPNGDFYNFPKISMNPHAYTQNGPRKYVTATSCHVVEWAAKKGIPLIFKWDDSNEVKHEYAKRYQAIAGEYGVDLAEIDHQLMILVNYSEDSEKAKEETRAFISDYILAMHPNENFEKKLEEIITENSVGDYMECTTAAKLAMEKCGTKGILLSFESMSDFTHQINAIDIVNDNIKKYHM
What is the function of this protein?
Light-emitting reaction in luminous bacteria.  The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity.
What are the official names of this protein?
Alkanal monooxygenase beta chain, Bacterial luciferase beta chain.
What is the protein family that this protein belongs to?
Belongs to the bacterial luciferase oxidoreductase family.
Protein: AIMP_BPSPB
Sequence: MKKLIMALVILGALGTSYISADSSIQQASGDYEVAGMPRGA
What is the function of this protein?
Peptide which is released by the infected host bacteria and acts as a communication agent that affects the latency versus replication (lysogeny-lysis) decision for any new infecting virus from the same specie.  High concentration of arbitrium peptide results in increased lysogeny in the upcoming viruses.  The arbitrium peptide is secreted by infected bacteria and, after several cycles of infection, accumulates in the extracellular medium.  When a virus from the same specie subsequently infects an uninfected bacterium which has internalized the peptide via its OPP transporter, the peptide will binds to the viral AimR transcriptional regulator and prevents AimR transcriptional activation of the aimX locus.  Inhibition of aimX transcription promotes lysogeny.
What are the official names of this protein?
Protein AimP, YopL protein.
What are the subcellular locations of this protein?
[Arbitrium peptide]: Secreted.
Protein: BR2E_PELLE
Sequence: GIFDKLKNFAKGVAQSLLNKASCKLSGQC
What is the function of this protein?
Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.
What are the official names of this protein?
Brevinin-2Ee.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMN6_YERPG
Sequence: MGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGCGSGLIALMIAQRSLPQVQIDGVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHPHQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLNCAEKLITEDGMFCVVLPHELGIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGVYSPEFCQLISDFYLNY
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND_HETP5
Sequence: MKSYYFESNEPVSVQQLNNINVLYYPMPMPDYQEKLDQICQERGYKNRDEVKLNENTENLDAKLKIFFEEHLHDDEEIRFILEGSGFFDVRDANDQWIRIRVEKGDLIIVPANMYHRFTLTETKQIHACRLFTDAPKWVPINRHQQ
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: RL34_UREP2
Sequence: MKRTFQPNNRKRAKVHGFRARMKTKNGRNVLARRRLKGRHSLTVSSEK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LHDAG_HDVM2
Sequence: MSRSESKGKRAGREQILEQWVDGRKKLEELERDLRKIKKKIKKLEEENPWLGNVKGILGKKDKDGEGAPPAKRARTDQMEVDTGPRKRPLRGGFSDKERQDHRRRKALENKKKQLSAGGKNLSKEEEEELKRLTEEDERRERRVAGPSVGGVNPLEGGPRGAPGGGFVPNMQGVPESPFTRTGEGLDVTGNLGFPWDILFPADPPFSPQSCRPQ
What is the function of this protein?
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding.  Packages the HDV ribonucleoprotein in hepatitis B virus empty particles.  Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg.  May inhibit viral RNA replication (By similarity).
What are the official names of this protein?
Large delta antigen, L-HDAg, p27.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=isoprenylated in the cytoplasm, and translocates in the nucleus possibly after phosphorylation. Translocates after to nuclear speckle, then to the ER membrane where interaction with Hepatitis B virus antigene takes place (By similarity).
Protein: AGRL4_MOUSE
Sequence: MRLLPLLVGFSTLLNCSYTQNCSKTTCLPNAKCEVHNGVEACFCSQGYSGNGVTICEDIDECSESSVCGDHAVCENVNGGFSCFCREGYQTATGKSQFTPNDGSYCQDIDECSESSVCGDHAVCENVNGGFSCFCREGYQTATGKSQFTPNDGSYCQESMNSNCHLEHACIAANINKTLKRIGPITEQTTLLQEIYRNSEAELSLMDIVTYIEILTESSSLLGHPNSTTSYKDAHFNSTLTEFGETINNFVERSTHKMWDQLPTNHRRLHLTKLMHTAELVTLQIAQNTQKNSQFDMNSTDLALKVFAFDSTHMKHAHPHMNVDGGYVKISPRRKAAHGTTGNVVVAFLCYKSIGPLLSSSDNFLLDTQNDNSEGKEKVISSVISASISSNPPTLYELEKITFTLSHVKLSDKHRTQCAFWNYSVDAMNNGSWSTEGCELTHSNDTHTSCRCSHLTHFAILMSSTSSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLIGININTNKLVCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSASLGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCYENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR
What is the function of this protein?
Endothelial orphan receptor that acts as a key regulator of angiogenesis.
What are the official names of this protein?
Adhesion G protein-coupled receptor L4, EGF, latrophilin seven transmembrane domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURG_PELUB
Sequence: MNKKILISTGGSGGHVIPATIIYKHLEDNFDVSMTSDFRGVKFLNKDEYNLKIFNVRPISKNLLIIPLDFIFMIFLIFKSISFFRKNKIDTLISTGGYMSLPLCLGARILNIKLLLFEPNMVLGRSNKFFLSYCQKIFCYSNNIKKFPIKFKNKIKVIPALLRKNFYNKRDYNKSLDTINLLIIGGSQGAKIFDDLVKNAIIELAKNYKLKIYQQTNSINFESFKKIYEDKNIQCELFNFNDDVVNFMQKTDLCITRAGASTLAELNFTETPYLAIPLPTAKDNHQFENAHFYNKLGFNWLLNQKEIDEKTLLNKLINIIDNKEEYLVKKKNMKDFNYENTWNNINLKIISVINEN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TYSY_NITOC
Sequence: MKPYLELIQKILDTGVERDDRTGTGTWSIFGHQMRFDLRQGFPLITTKKLHIRAIFIELLWFLRGETNVKYLHDHGVTIWDEWADEQGELGPIYGYQWRSWPLPDGGYLDQMAKTLTQIRNHPHSRRHVVVAYNPACVDEMALPPCHALFQFYVAQGRLSCQLYQRSADVFLGVPFNIASYALLTHLIAQQCDLDVGEFVWTGGDVHLYRNHLEPARLQLTREPLSLPHLRIKRRPPSLFEYQYDDLEIVDYQSYPAIKAAISV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_TREPA
Sequence: MKRPERRTLVGLVTSDKMHKTVTVRITTKKLHALYKKYVSRSKKYQAHDEENTARAGDVVRIAESRPLSRRKRWRLVEIVERAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: GRB2_XENTR
Sequence: MEAVAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLGKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQVHGGDRATNLLQQPTYVQALFDFDPQEDGELGFRRGDFIQVVDNSDPNWWKGTCLGQTGMFPRNYVTPVNRNM
What is the function of this protein?
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.  Promotes meiotic reinitiation during oocyte maturation.
What are the official names of this protein?
Growth factor receptor-bound protein 2, Adapter protein GRB2, SH2/SH3 adapter GRB2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome. Golgi apparatus.
Protein: RF1_SODGM
Sequence: MKSSIVAKLEALQERREEVEVLLGDPGVISDQIRFRALSKEYAQLSDVTRCFQHWWQVQEDIHTAEHLLQDPEMRDMAQEELLASGASLEQLEQQLQVLLLPRDPDDERGCFLEVRAGTGGDEAALFAGDLFRMYSRYAETRRWKVEIVSASYGEHGGFKEVIAKVSHEGAYGLLKFESGGHRVQRVPETESQGRIHTSACTVAVMPEIPEAELPEINAGDLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGLVVECQDERSQHKNKAKALAVLGARLRAAEVQRRQQEESSTRRNLLGSGDRSDRIRTYNFPQGRVTDHRIGLTLYRLDEVIEGKLDMLIQPIMQEYQADQLAALSETP
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFB_ALKAM
Sequence: MLLDGTLIQLLFLLGFMVFMVMLFQRAHIPASIAYLLVGVLLGAHTAGPVISEGYIHKIAEFGIVFLLFTIGLRFSWQQIYQLRHTILGLGTAQVGLTTLLVALLLWAMGVASVVAFVIGAVFAQSSTTIISKQLLEQGEDQSRHGRLGISLSVFQDITAVPFIIVIPVLGVAMAQDIASTLGMALFKAVLATALVVLVGRYLLRHLFHRVSSSDSAELFTLTVLLVCLAAAWLTQSLGLSMAFGAFLAGMVMGETEFKLQVEAAIRPFRDVLLGIFFVSIGMLLDPMLLPEIGHIALAGALLLLLIKIVLVTALVLATGVALETAFRTGLILAVGGEFGFALLALALEGGTLDSRSSQIILTSVLLSMMLAVFLIRYNLQLSRFVVGRWIGQAAVSSEPFDDIEQHGLQQHVVIAGFGRIGQGVAQFLQKEQVPYIGLDLDAARVKNARLADVPVFYADSTDPDTLIAVGLAKARLLVISHEDLSAALTTLRHARTLHPDLPVIVRTRDESHVAELRQAGATEVIPETIEAGMMLTSHVLLMLNVPARRVNQLVQEQRINRYQLLRQQFRGSADLLKTQQQEQLKAVLLAEGSPAIDQSLQMLDLAQYGIQLTELVRAHNRIEQPSLDMVLQENDVLVLFGSAEALEQASLVLTHRLAAD
What is the function of this protein?
May operate as a K(+)/H(+) antiporter.
What are the official names of this protein?
Putative K(+) efflux antiporter KefB.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KEA (TC 2.A.37.1) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLSA_SHESA
Sequence: MPEQALLEEVVDKVRPLLGQGKVANYIPALANVDAGKLGIAVTTIDGETIGAGDYLEPFSIQSISKVFSLTLALTLYEETEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLYDGAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDNQGNSLAGTAMLEHLSQRLGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: OPPC_MYCPN
Sequence: MDKHQKFDQSLFQRVDINVLKRSDQLIGKPTTNFVEIMKRLFQNKWAILFFLLIVLIILLAIIVPLASPYSAVTPVSNNALAQNLPPRYLWNGAGDIQVEKITARSIAEVAQSSGVLVGKLPEASSNPLATNVKYNIAPYQLAELKNYYPLLGTNGLGVDIWTLLWASMAKSLWIAIVVALVSMVFGTIYGAIAGSFVGRAADNIMSRIIEIIDLVPSILWIIVLGATFRFGGVKQFDDSVVIFTLIFVFWTWPAATTRIYILKNKDTEYIQAARTLGAKQIRIIFVHMLPVVTGRLAVVFVSLIPAVIGYEASLVFLGLKPATEVGLGALLNQVTSSGNIALITSSIVSFAILTVSTRVFANALNDAIDPRVIRR
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Oligopeptide transport system permease protein OppC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.