PharMolix/UniProtQA huggingface dataset:
Protein: MTNA_SULDN
Sequence: MQGNYKALWLNDDLFDECLEVIDQRLLPFIYDTRHLTTTEEVVTAIKNMTVRGAGVIGSVAAFGIYIAAMEVEGDYELLKEKALLIRESRPTAINLMWAVDKMMELLSASANLIEDARSFAIELNDAEALESQKIAEFGCEIIEEILKQKNKTRINILTHCNAGWLAVIDEGTALAPIYEAKRRGIDVHVWVDETRPRNQGASLTAWELSKEGIEHTIIADNMGGLLMQRGEVDMVIVGADRVSANGDVANKIGTYLKALAAHDNGVPFYVAIPASTFDFEIKDGVKEIPIEERSGDEVKFIRGVDEDGVLRRVRITPEDSPTKNYGFDVTPARLISALITNKGVCRANFDEIKEKFRG
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: SYE_CHLFF
Sequence: MAWENVRVRVAPSPTGDPHVGTAYMALFNEIFAKRFKGKMILRIEDTDRTRSRDDYEKNIFSALQWCGIQWDEGPDVGGPCGPYRQSERTEIYKKYAELLLKTDYAYKCFATPKELEEMRAVATTLGYRGGYDRRYRYLSPEEIEARTLEGQPYTIRLKVPLTGECVLEDYCKGRVVFPWADVDDQVLIKSDGFPTYHFANVVDDHLMGITHVLRGEEWLSSTPKHLLLYEAFGWKAPTFLHMPLLLNPDGTKLSKRKNPTSIFYYRDSGYVKEAFVNFLTLMGYSMEGDEEVYSLEKLIENFDPKRIGKSGAVFDTRKLDWMNKHYLTHDGSPEHLLSRLKDWLINDEFFLKILPLCQSRITTLAEFIGFTGFFFSVLPEYTKEELLPAAISAEKAAILLYSYVKYLEKADLWVKDQFYQGSKWLSEAFQVHHKKVVIPLLYVAITGKKQGLPLFDSMELLGKPRTRMRIVHAQNLLGGVPKKVQAVIDKVLKEEDFESKTLEF
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_STRT2
Sequence: MARVKGGVVSRKRRKRVLKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARLNGLSYSQLMHGLKLAEIEVNRKMLADLAVNDAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PSBM_EUCGG
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQSD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL22_XENLA
Sequence: MAPVKKTVTKGSKKKKQLLKFTLDCTHPVEDGIMDAANFEQFLHDRIKVNGKVGNLGGGVVSIERSKSKITVSSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEDED
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3798_CLOBM
Sequence: MLSYYAFIFFAKIMEVALMTIRTVLITRGEKLYGSIIGFIEVTIWLYVTSSVLSGIKDDPIRMVVYALGFTCGNYMGCVIEEKLAIGLLTINVITSESDGKRLAEILRDENVGVTMVDAEGKIEQKKMLIIHAKRKRREEIIRTIEGSDINAMISVNDIKTVYGGYGIRK
What are the official names of this protein?
UPF0316 protein CLK_3798.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BPTA_BORAD
Sequence: MGKIFFLGLLSICIFLVFFFYKQKVNNVIYNKIVEKFEDNVFIDETYTYLFKDSNLKELVFIKSQLIVPEFENKNMMKATGYLADAYRALSTVYKFDFKVHDNKILGFKSVIFEGFEDARVSKHENNLPGEKWQQLKDFNIGDPNVNEKFFHLEFPFVVKNTLCVTISKRFFKKIKKLKRLKIVLISNEDREYKIDIENFLPKYNL
What is the function of this protein?
Virulence-associated protein essential for survival of the bacterium within the tick host and therefore within the natural life cycle of the spirochete.
What are the official names of this protein?
Protein BptA, Borrelial persistence in ticks protein A.
What is the protein family that this protein belongs to?
Belongs to the BptA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: NRG1_HUMAN
Sequence: MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQDPIAV
What is the function of this protein?
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors.  Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors.  The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart.  Isoform 10 may play a role in motor and sensory neuron development.  Binds to ERBB4 (PubMed:10867024, PubMed:7902537).  Binds to ERBB3 (PubMed:20682778).  Acts as a ligand for integrins and binds (via EGF domain) to integrins ITGAV:ITGB3 or ITGA6:ITGB4.  Its binding to integrins and subsequent ternary complex formation with integrins and ERRB3 are essential for NRG1-ERBB signaling.  Induces the phosphorylation and activation of MAPK3/ERK1, MAPK1/ERK2 and AKT1 (PubMed:20682778).  Ligand-dependent ERBB4 endocytosis is essential for the NRG1-mediated activation of these kinases in neurons (By similarity).
What are the official names of this protein?
Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1.
What is the protein family that this protein belongs to?
Belongs to the neuregulin family.
What are the subcellular locations of this protein?
[Pro-neuregulin-1, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Note=Does not seem to be active. SUBCELLULAR LOCATION: [Neuregulin-1]: Secreted. SUBCELLULAR LOCATION: [Isoform 8]: Nucleus. Note=May be nuclear. SUBCELLULAR LOCATION: [Isoform 9]: Secreted. Note=Has a signal peptide. SUBCELLULAR LOCATION: [Isoform 10]: Membrane; Single-pass type I membrane protein. Note=May possess an internal uncleaved signal sequence.
Protein: ASNA_CROS8
Sequence: MKTAYITRQRQISFVKAHFSRLLEEKLGLLEVQAPILSRVGDGTQDNLSGCEKAVQVNVKTLPQAQFEVVHSLAKWKRKTLGQHDFSAGEGLYTHMKALRPDEDRLSPVHSVYVDQWDWERVMGDGERHLGTLKQTVESIWSAIKETELAAAERSGLTPFLPDAIHFVHSETLQRRFPELDAKGRERAIAKELGAVFLIGIGGKLADGKRHDVRAPDYDDWTTPTESGFAGLNGDILVWNPLLEDAFEISSMGIRVDADTLKRQLALTGDQDRLALEWHQALLNGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPEQVQSTVAELL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO1A1_NEODO
Sequence: SVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGSGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGQMGPRGIPGERGRPGASGPAGARGNTGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGAPGPSGARGERGFPGERGVQGPPGPAGPRGSNGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGPPGPIGNLGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGKGPRGETGPAGRPGEVGPPGPPGPGEKGSPGADGPAGAPGTPGPQGISGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPMGPPGLAGPPGESGREGSPGAEGSPGRDGSPGPKGDRGETGPGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPAGPAGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: RS161_ARATH
Sequence: MATQPATESVQCFGRKKTAVAVTHCKRGSGLIKLNGCPIELFQPEILRFKIFEPILLLGKHRFAGVNMRIRVNGGGHTSQVYAIRQSIAKALVAYYQKYVDEQSKKEIKDILVRYDRTLLVADPRRCEPKKFGGRGARSRYQKSYR
What are the official names of this protein?
40S ribosomal protein S16-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: UVRB_ECOHS
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETF2_MSEPV
Sequence: MDYIETFINPQVIFLYNENKKIIKTIFLSKDSMIEDSHVMTVYNYLLSSHSDIFENKPQFINDHVILTFTLEQARGYIKNILGLSDDIILFSIWNNFDYYLKNGIFDPYNIQNMLLVEPNDDKSILYNIYQNIVEGAVFCVTTNKNIGSQLARSNVYSSVYRDYISEIINNIYKNRYAMKSSIIDAMEYSINIDFQDLLRISNIPDYNKTLCISAYNNFYIKGNKITILDNFDSMYESKYLKIYDKNININIYDDVLYVKKLSDFTDILNKYNIKSINIKSLKPKTTIYVYFNTFLNPNLTIEFDFDFFINDTKKTKNIFIDLTGKINIMTSQSHISYRSYNISTDLAKYFTLFILGYSHIFNKVQSKAKIKKIDELYPSRYCQNYKDIKRQPILIDHIDESRLIKISDNFYTGKEDSTKTYQRKGTKKVYDPLKHGDVYIDSNGLKYQCSSIYYSNMGFLGNIYSATGICYPCCYSKPKIRDTIFNTCVHGTKFIHEEKINPIIVNYGRLILNPSNLSNLPYKLNLLLNSKNQIRIVKHTNRIILAKNYTVIMAYQPSTIIKDFNEMYNFIIENNAILFNDNMMYTHKDIIENNNITPSIFILIQNRIHQFKNINKEQDNDNITVSIVDSNKINLIKNKFSVLNNITKEISENGITVKNGKCYIDGELVKNKNITYFTKFSNITIRPKSISEYILKYFKKYIDDNIYTDNYFLFNKIFVTNILNIMHENDAILNDFSVIQKKLDDMSSDYIVTQSKTYN
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa (RAP94) to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters (By similarity).
What are the official names of this protein?
Early transcription factor 82 kDa subunit, ETF large subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae VETF large subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: RECA_CHLPN
Sequence: MNLPDRKKALEAAVAYIEKQFGAGSIMSLGRHSATHEISTIKTGALSLDLALGIHGVPKGRVIEIFGPESSGKTTLATHIVANAQKMGGVAAYIDAEHALDPSYASLIGVNIDDLMISQPDCGEDALSIAELLARSGAVDVIVIDSVAALVPKSELEGDIGDVHVGLQARMMSQALRKLTATLSRSQTCAVFINQIREKIGVSFGNPETTTGGRALKFYSSIRLDIRRIGSIKGSDNSDIGNRIKVKVAKNKLAPPFRIAEFDILFNEGISSAGCILDLAVEYNIIEKKGSWFNYQEKKLGQGREFVREELKRNRKLFEEIEKRIYDVIAANKTPSVHANETPQEVPAQTVEA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FENR_LACP3
Sequence: MSVQHVYEITVIGGGPVGMFAAFYAGLRQADVLLLESLDELGGQTGNLYPAKILYDIGGFPHVSGKDLVTQLKTQLVHFHPEVKTATEVQTIDQDPDGFFTLHTSQGDFRSKTVIVATGGGAFTPRKLAVDYDPALEGKKLFYFVQDLETFRDQEVAVAGGGDSAIDWALALEPVAKHVSLIHRRAKFRGLEASVAALEKSSVTIQTPYLIESVTPQDDQLAIQLKEVRGEAQPTLTVDKLLINYGFVTDKHHLQAWQLDTDRNGILVDTQMQTSRPGIFAIGDAVSYAGKLPLIASGFGEAPTAINEALSRLYPDRRQALHSTQLYH
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: DEND_CUPNH
Sequence: MNVLITGGAGFLGLQLARLLLQRGTLNLDGQPVAIKRLTLLDVVAPQGLDDARVRVVTGDLSDPAVLRQAIDTDTGAVFHLAAVVSGQAEADFDLGMRVNLDASRALLETCRELGHQPRVLFTSSVAVYGGQLPPVVQDDTALNPQSSYGVQKAIGELLLSDYSRRGFVDGRVLRLPTISVRPGKPNAAASSFASGIIREPLSGVAANCPVAPETPLWLLSPRAAVAALVNGIELAGERLGNRRVVNLPGLSVTAAGMIEALRRVAGNAVADRVTWEREARVENIVGTWPAAWNAERALALGFQSDASFDEVIRAYMEDAGLAK
What is the function of this protein?
Catalyzes oxidation of D-erythronate to 2-oxo-tetronate.  Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
What are the official names of this protein?
D-erythronate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: RS9_STRZJ
Sequence: MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADLRLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAGLLTRDSRKVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: LPXD_DESVH
Sequence: MVRRLSEIAGLLGLELRGEDREVSGVNTLEAAGPDEISFLANPRYMGQLSTTRAGAVIVAAEHAQDVAVALVSANPYFDFGRTLALFARKQGSFEGVSEQAVVHPEAVVGEGCAVYPHVYIGPRARIGAGTVLFPGCYIGEDCVVGGGCTLYPNVVLMAGVEIGDDCILHAGVVLGADGFGFARTEFGIQKIPQVGTVRIGSDVEIGANTTIDRSVLGVTTVGDGTKIDNLVMLGHNVEMGRNCLIVSQVGISGSTKVGDDVTMAGQVGVAGHLSIGSGVTIGPKSGVAKDIPAGETVGGAPAVDKSTYMRTLTVMPKLPDMYKRLGKLEKELAELKKSLSEEQ
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RL13_BIFLO
Sequence: MKTFTPKPADLTHDWYVIDATDVVLGRLATQAAILLRGKNKPTYAPHADSGNHVIIINADKIALTGNKMGKELYSHSGRPGGLRRDSYAELLEKNPERIIKNAVKGMLPKNRLAKVQLDRLRIFRGAEHPHTPQKPQVFEIAQVSQQAK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: 3SA2A_NAJSP
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCNKLVPLFYKTCPAGKNLCYKMYMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 2a, Cardiotoxin 2a, CTX-2a, Ctx2a.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: PRMA_SHEON
Sequence: MPWIQLRINTNSDDAETISDLLMEEGAVSITFEDGKDTPIFEPKLGETPLWRDTVVVALFEADTDLTPTIEMLKTLPFLGEHFSHKIEQIEDKDWVREWMDNYHPIQFGKRLWICPSWREVPDPTAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLSNEEVIDFGCGSGILAVAALKLGAKKVTGIDIDYQAIDASKANAERNDVADQLELYLPEDQPADLKADVLVANILAGPLRELAPLIAERVKTGGKLALSGLLKEQAQEISDFYSQWFDMDEAAHKEDWSRLTGTRK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_PETMO
Sequence: MEILVYIIIGIAIFILSLLVGINIGNRRMISTLATKKEELEVEIKNKQKEIEKMLKNAEEEAKALKQKELLEAKEEIHRLRQEFDSEAKQQREELKANEERLIRKEESLAKKEENLEKLKEKLEVQHENVLKLEKELETKLNEIAKMTEEEARQVVINEARDKYEREIAQKFKEIKDHYEEESKKYARWVITTAIQRYASDVTNEITTSTVALPTDDMKGRIIGREGRNIRTFEKLTGTDLIIDDTPEIVVISSFNPLRREIAKRTLEMLVADGRIHPARIEELYEKSKNEIQEYIKEVGKEAVMRVGIKQPHLEIIKLLGRLKFRTSYGQDVLEHSIEVAQFAGMMASELGLNVELAKRAALLHDLGKAVDHEVEGSHAIVGGQIAKRYGEKLEVVNAIQYHHNEVDPMTPEAVLVAASDALSASRPGARKETLENYIRRIEQLEEIAKSFRYVDKAYAIQAGRELRIIVQPDKVEDEIAEKLAHDISVQIEEKVQYPGVIKVTVIREKRSISYAS
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACHX_ONCVO
Sequence: IIDVHEIDQIMTCSVWLKQVWIDKKLSWNPEIYGGVSVLYVPYEMVWVPDIVLYNTVDSNYNITISTKATLRYDGQVTWDSPAIFKTLCQIDVRWFPFDEQNCHFKFGSWTYTEDLLNLELLDSDARYELEMNENGELNNITIFEEGIDLSDYYPSVEWDIMSRIAKRRTKNYLTSFSDEAFIDIIFYLELRRKPLFYTVNLVFPCVGISFLTIVAFYLPPRSGEKVTLCILILVALTVFYLLLKDIIPATSIALPLFGKYLLFTMIMVSLSVLVTVISLNLHFRRPSTHRMPIWVKWLFLRILPKILFMRRPTLIKVDEAVRRVADYRRGYNMIINRYEQKVNCDSCRNVNKRITQEIQKIYRSPHVIKAFENVCFIAQLLKKKDREAMIDEDWKFVARVLDRLFLLLFSIACFLGTILILFQAPSLYDTRQAIN
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor non-alpha chain.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: ACKA_ALKCK
Sequence: MAKIIAINAGSSSLKFQLLAMPEETVIAKGLVERIGLKKSIFTIEANGQQHELTEDIPDHAAAVKLLLKDLTGRGIIASLEEIEGIGHRVVHGGEKFNDSVVITDEVLQGIEEVSELAPLHNPANITGIKAFKEVLPNVPAVAVFDTAFHQTMPESAFLYSLPYEYYEKYGIRKYGFHGTSHKYVTHRAAELMETPIEELRILSCHLGNGASIAAVKGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPYIMEKTGQSVEEVVATLNKKSGLLGITGFSSDLRDIEAAAKEGDERAQVALDVFASRIHKYVGSYAARMGGLDAIVFTAGIGENSATIRERVLKGLSFMGVDVDLEKNNVRGKEAFIEKAGAPVKIIVIPTNEEVMIARDTVRLTS
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPA13_HUMAN
Sequence: MEASRWWLLVTVLMAGAHCVALVDQEASDLIHSGPQDSSPGPALPCHKISVSNIDFAFKLYRQLALNAPGENILFFPVSISLALAMLSWGAPVASRTQLLEGLGFTLTVVPEEEIQEGFWDLLIRLRGQGPRLLLTMDQRRFSGLGARANQSLEEAQKHIDEYTEQQTQGKLGAWEKDLGSETTAVLVNHMLLRAEWMKPFDSHATSPKEFFVDEHSAVWVPMMKEKASHRFLHDRELQCSVLRMDHAGNTTTFFIFPNRGKMRHLEDALLPETLIKWDSLLRTRELDFHFPKFSISRTCRLEMLLP
What are the official names of this protein?
Putative serpin A13.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACTZ_PNECA
Sequence: MEFNDVLTNQPICIDNGSGVIKAGFAGEDQPKSFFPSYVGRPKHLKIMAGAIEGDIFIGNKAQELRGLLKIKYPIEHGIVVDWDDMERIWQFIYTEELKTVSEEHPVLLTEAPLNPRTNRDQAAQVFFETFNVPALFTSIQAVLSLYASGRTTGVVLDSGDGVTHAVPIYEGFAMPSAIRRIDIAGRDVTEYLQLLLRKSGTIFHTSAEKEIVRIIKEKCSYVTLDPRKEEKEWINASISGGKDYTKEEEFKLPDGNVLRLGAERFRAPEILFDPEIIGSEYSGIHQVVVDAISRVDLDLRKSLFGNIVLSGGSTLTRGFGDRLLSEIRRLAVKDVKIKIFAPPERKYSTWIGGSILASLSTFRKMWVSAEEYQEDPDIIHRKSI
What are the official names of this protein?
Actin-2, Actin II, Centractin-like protein.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HIS7_PYRFU
Sequence: MRRTTKETDIIVEIGKKGEIKTNDLILDHMLTAFAFYLGKDMRITATYDLRHHLWEDIGITLGEALRENLPEKFTRFGNAIMPMDDALVLVSVDISNRPYANVDVNIKDAEEGFAVSLLKEFVWGLARGLRATIHIKQLSGENAHHIVEAAFKGLGMALRVATKESERVESTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.