PharMolix/UniProtQA huggingface dataset:
Protein: THIC_AROAE
Sequence: MNASEKFIAAKAHVDEAAVAPLPNSRKIHVEGSRPDIRVPMREISQADTPASMGAEPNPPIFVYDCSGPYTDPTAKIDIRSGLVALRQQWIEERGDTEVLADLSSEFGRSRAADKALDELRFPGLHRHPRRAKAGMNVSQMHYARRGLITPEMEYVAIRENMNRAAYVESLRTAGPTGEKMAKLLTRQHPGQSFGASIPEEITPEFVRSEVARGRAIIPNNINHPESEPMIIGRNFLVKINANIGNSALGSSISEEVDKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRMTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICDIMKAYDVAFSLGDGLRPGSIYDANDDAQLGELKTLGELTDIAWKHDVQTIIEGPGHVPMHLIKENMDLQLEHCKEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKQDVKEGIITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDKAKEFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVRDFAAKEGLKEDEALAKGMEVKAVEFVKSGAEVYRQV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RL39_YEAST
Sequence: MAAQKSFRIKQKMAKAKKQNRPLPQWIRLRTNNTIRYNAKRRNWRRTKMNI
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L39, L46, Large ribosomal subunit protein eL39, YL40.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO94_CAEEL
Sequence: MEEIENQSKRRIVSKKEINELSIYIGGFKYWKFLNEDCKIEVLKYLDYCSRCQLSICSKSDHKLVSITPLYVYEIEISDNERSLHSTSTKDFENIVVRVKFSQFSGYRFEVVFWQVEEDVHIRWFKYFGFKQKSVRSLIWKSCNYYEQSVKFAEKWMKVCNYEFQSINVDMNKYPMKSSTVRSLARCKTIRINATDIATYSWWLEKCPEKLDYLELKTLYSNKDTFTIPTDFLDFSQIKNAGTFYFWCRSAFTDEQFLNLKAKKFGFHCVNITANGINDFIKKWVNGHGVNEFQKALLWSAKLNNSFMIMRGIEFRSWDQTFREQEAEFCSAFNEEFLDGEKIQVYSRIDPYESITIYFSPDTISIIATGHRMTRNKKTFTRYQVP
What are the official names of this protein?
Uncharacterized F-box protein T20B12.4.
Protein: MNTP_METMJ
Sequence: MDLVTTLLIAVGLAMDAFAVSISGGATLREERLRWAVIAGALFGGFQAGMPVLGWLGGMGLASFVGTYGPWIAFLLLALIGGKMIAEAVRGDGESVRFENGATVLLLLAVATSIDALAVGVSFAVLDTAIALPAITIGVVTFAFSAAGVLLGSAFGHIMGRKACIVGGIILVGIGLRILLEHLFF
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RABEK_DANRE
Sequence: MELIPVLEPEQKPQNRHWYVLEPTGAAPGVSVGHTCSFLPAAHHHDEDGGGKGKIVIVGGANPSGSFADSYIINLDTHQWDLPDWEGLQARYEHCSFTPESEPQSLWVFGGAEKSTNRNCVQALRFSDGGEGRRFWQSVQVTGVPPSGRTYHTNSACVGNRLFVFSGGEAGSSAVTDAQLHVFDAVSVTWTQPDTTGTPPAQRHGHVITAVGSDIYIHGGMSGEKFHSDMFTLNTESLKWQKVKAKGDLPPGVAAHSSVTFNKNIFIFGGMTADGATNSMFKFQCDKQRWTLLKFEGDLPPGRLDHSMCLLPWRVKMEDSEHADVQHLCFVFGGMDTQGVIFNDCLVTVLT
What is the function of this protein?
Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
What are the official names of this protein?
Rab9 effector protein with kelch motifs.
Protein: ASTE_ACIBS
Sequence: MQDFLALTLQGEQPATREGKQANFSWRWLGEGLLECTPHAQYDKAVVLSAGVHGNETAPIELLSHLCTDLFAGRLKLAVRLLLVLGNPYAMRQGKRYVHDDVNRMFCGGYKNLPVTEESKRAEVLEQTVATFFQESSSQAKRYHYDLHTAIRASLLPTFALFPYQTHSYDADLTASLEAADLDALVYHNAVGKTFTHFTSENFKAASATLELGKALPFGQNDLSQFASIDEVIRNVVSEQALPVRNKPKIRVFQVSDSLIKKDEEFHMNLSAEAPNFSTFTKGEIIATQPSGNYVVEQDQVWILFPNPNVKIGLRAGLVLTETI
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: LPXC3_ARATH
Sequence: MRLPVTVKATKPSFLVIWIRYSSAASSPTVSLNPSGRLQQTLAGSVEVKGKSLHSGKFSTVKLNPEIAGAGRFFEFRSRFIPASIEFAQESPLCTTLLKDELKIRTVEHLLSALEAKGVDNCRIQIESESSDDREVEVPIFDGSAKEWVDAIQGVGINAAQNHDGESVEKMVAHVNKPVYVCKNDTFVAAFPALETRITCGIDFPQVPAIGCQWFSWRPIHESSFAKDIASSRTFCVYEEVERMREAGLIKGGSLDNAIVCSAEHGWMNPPLRFDDEACRHKILDLIGDLSLVSRGGNGGLPVAHIVAYKAGHALHTDLARHLTMD
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell.  Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential).
What are the official names of this protein?
Probable UDP-3-O-acyl-N-acetylglucosamine deacetylase 3, mitochondrial, UDP-3-O-acyl-GlcNAc deacetylase 3, Protein LIPID X C3, AtLpxC3, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase 3.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MIAA2_BACFN
Sequence: MPDYDLIAILGPTASGKTPFAAALAAELNTEIISADSRQIYRGMDLGTGKDLEDYTINGRQIPYHLIDIADPGYKYNVFEYQRDFLTAYETIKQKGCLPVLCGGTGLYLESVLKGYRLIPVPENQELRVRLAEKSLEELTAILSSYKTLHNSTDVDTVKRAIRAIEIEEYYAKTPIEEREFPQLNSLIIGVDIDRELRREKITRRLKQRLDDGMVEEVRRLLAEGIQPDDLIYYGLEYKYLTLYAIGKMTYDEMFTGLETAIHQFAKRQMTWFRGMERRGFTIHWVDASLPMEEKINFVKQKLKEF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 2, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 2, DMAPP:tRNA dimethylallyltransferase 2, DMATase 2, Isopentenyl-diphosphate:tRNA isopentenyltransferase 2, IPP transferase 2, IPPT 2, IPTase 2.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RS11_ARCFU
Sequence: MAEKKKGGRWGIAHIYSSYNNTIITITDITGAEIIARVSGGMIVKADRDEGNPYTAMQAALRAAAIAKEKGIDGVHIKVRAPGGNKHTTPGPGAQAAIRALARAGLKIGRIEDVTPIPHDGTRPPGGKRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: YIDC_SINFN
Sequence: MMENNRNYFVAIALSVLILVAWQYFYVNPRMDKDRIAAEKAQQTQQVQPQQGGQQPAPGQALPGGAVPGESRDQAVAKSARVAIDTPALSGSINLTGARFDDLKLKGYHETVDPKSPVITLFSPAETADGYFTEIGYIGNDASGSVPGPQTVWTLSGGEKLTPATPVTLTYTNDKGITFARTISIDENYMFQVVDSIKNDGSAPVSLSSYGRVTRFNKPTTPSIYVLHEGFIGVAGGSLQEVGYSKIEENLPVEPGKTTGGWHGITDKYWAAAIVPPQETPFDIRFSHFTDGRPRFQSDYKGDAVTVAPGQSAEVKNLVFAGAKEVQVVDTYTTAYAIPKFEKLIDWGWFWFITQPMFKMMDFFFRLFGNFGVAILVTTIVVKLIFFPLANKQYASMANMKKVQPKMEELKKKFGDDRMGLQQAMMQLYKDEKINPLAGCWPILIQIPVFFALYKVIYITIEMRHAPFFGWIRDLSAPDPTTIVNLFGLLPFDGPAFLHLGIWPIIMGVTMFLQMRMNPTPPDPTQAMLFTWMPLVFTFMLASFPAGLVIYWAWNNTLSITQQSIIMKRQGVKIELFDNLKGLFTKRPKPAE
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBN_CAPBU
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TMCAL_STRGC
Sequence: MTVTGIIAEFNPFHNGHKYLLEQASGLKIIAMSGNFVQRGEPAIVDKWTRAQMALEAGADLVLELPFLVSVQAADFFAKGAVDILERLDIEQLTFGTEEVLDYESISKVYGQKAEQMEAYLAGLPDSLSYPQKTQAMWQEFAGLNFSGSTPNHILGLAYSKAVAVKNIKLCPIQRQGAGYHSLSANQEFASATALRQNLDQPDFLKKFTPVHHLLETAPKVTWSDLFPYLRYQIVTCPDLTSFYQVNQELAVRIREALKSSETIEELVEQVATKRYTKARIRRLLTYILVGARQEEVPSGIHILGFSEQGRQHLSQLKGKVELVSRIGKKPWDSLTQQADKVYQLGNPALKEQNFGRVPVILL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIDE_LEGPH
Sequence: MPKYVEGIELTQEGMHAIFERMGHPNITSGTIYNGEPTIDKGALDRQGFMPVLTGVSPRQDSGHWIMLIKGQGNQYFLFDPLGESSGKYYQNILAKKLPGATLSVIPNNAGLNMGLCGYWVASVGLRAHAALTQPIPPSLRNLGQTITQEMRDELTQDGSEKITQWLRAVGNEFPDGDIQPDATALRRATEKNVRIDEFQPVLTGTSPKEISINPTAPQEVSVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREESDDEDEEESGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQTKITPIKRAFQSSSEKARRQPNMDEIAAARIVQQIMANPDCIHDDHVFLNGQKLEEKFFRDLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIKHDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLMDTSRSPAPKTLFRGLDLSEEFKNKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDGLLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPRHESGYAVGPLLKMQTPKLEEIQRLVEQAREEPDLERVFNLQSRVARQAKFSTESGYKTFLNEKVAPVLEQSLNGLLDNNVTILGKVLSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQALRNIPSEKEMQTMLSISGGLRGQIQRAKQDLTETLEPLQRAITAKLVSDQEKVKVRYEKLIAGIPQQIADLEKAELADLAKVKKVVSRFNHLQEELKLLRNEKIRMHTGSEKVDFSDIAQLEAQLQKIHTKLYDAYLVELTKEISALVKEKPKNLADVKRMVSNFYAMSADIEQLRQEKIKEHGESKDPIDMSDIDKLKEELQKINQFLVKAMGTNIRVSLNQMEVKTFDAQEKEAQQNLKQLDALINKLESSDAVQKQKEELEKLNQLLVEKRKAYPAMVQLQFRSEALIIHLRELCEAHQAQMAKTRNVRAQEITNGRWKVQWLTDWVGLTTDERVTLANKEKELAKFKEDLNNDEYDLQELISNLAEKNPSELEEAIGISKESAQKLHKLLTHLNHSTTFMSKIEQRLQSIDELLNEFGKQAPRTEMIKTVEEKQGTLLRL
What is the function of this protein?
Effector that interferes with the host cell ubiquitin pathway and is required for intracellular bacterial replication.  Catalyzes the ubiquitination of several host Rab small GTPases associated with the endoplasmic reticulum during L. pneumophila infection, without engaging the standard cellular enzyme cascade (E1 and E2) (PubMed:27049943).  Transfers an ADP-ribose moiety from NAD to the 'Arg-42' residue of ubiquitin in a reaction that releases nicotinamide (PubMed:27049943, PubMed:29731171).  The modified ubiquitin is subsequently transferred to serine residues of the substrate protein via a phosphoribose linker that results in the release of AMP (PubMed:27912065).
What are the official names of this protein?
Ubiquitinating enzyme SidE.
What is the protein family that this protein belongs to?
Belongs to the SidE family.
Protein: GAB3_HUMAN
Sequence: MSAGDAVCTGWLVKSPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSSKPIRVIDLSECAVWKHVGPSFVRKEFQNNFVFIVKTTSRTFYLVAKTEQEMQVWVHSISQVCNLGHLEDGADSMESLSYTPSSLQPSSASSLLTAHAASSSLPRDDPNTNAVATEETRSESELLFLPDYLVLSNCETGRLHHTSLPTRCDSWSNSDRSLEQASFDDVFVDCLQPLPSSHLVHPSCHGSGAQEVPSSRPQAALIWSREINGPPRDHLSSSPLLESSLSSTIQVDKNQGSLPCGAKELDIMSNTPPPRPPKPSHLSERRQEEWSTHSGSKKPECTLVPRRISLSGLDNMRTWKADVEGQSLRHRDKRLSLNLPCRFSPMYPTASASIEDSYVPMSPQAGASGLGPHCSPDDYIPMNSGSISSPLPELPANLEPPPVNRDLKPQRKSRPPPLDLRNLSIIREHASLTRTRTVPCSRTSFLSPERNGINSARFFANPVSREDEESYIEMEEHRTASSLSSGALTWTKKFSLDYLALDFNSASPAPMQQKLLLSEEQRVDYVQVDEQKTQALQSTKQEWTDERQSKV
What are the official names of this protein?
GRB2-associated-binding protein 3, GRB2-associated binder 3, Growth factor receptor bound protein 2-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the GAB family.
Protein: RS4_SULIN
Sequence: MGDPKKSRKKWESPGHPWIKERIGYEQELLGKYGLRNKREIWIAQSIIRKFRHQARSLLALPPAERAVREKQLVGKLLKMGLLKRETATVDDILSLTEQDLLERRLQTIVYKKGLANTTYQARQLIIHGHIAVNGKRVTSPGYIVNVDEENLIDYYVTSSFKSRPPVMAQQEGGEAGVKQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: SAP18_CAEEL
Sequence: MSNGQLVSQVTVGHDKPLDREKVCPMLLRVFVANNRHNPMSEYNSRNGGSVPPSELQMHTWMDCSLRELTSLIKEVNPDARRKGTTFDFAIVQADRGSPRYILRDVGNTTNGERGIDDNKTLQQCKFEVGDFVDVAISLPSQGRRFNNREQGDRFDHRQRQRSPIR
What is the function of this protein?
Acts in transcription repression.  Involved in the tethering of the SIN3 complex to core histone proteins (By similarity).
What are the official names of this protein?
Probable histone deacetylase complex subunit SAP18, 18 kDa Sin3-associated polypeptide.
What is the protein family that this protein belongs to?
Belongs to the SAP18 family.
Protein: RIMP_METPB
Sequence: MAEPTEKRLVSETGVAARVAQIVEGPIEGLGFRLVRVKISNTNGCTVQIMAERPDGTMGVDECETVSRAISPILDLEDPVGGAYYLEISSPGIDRPLVRVSDFERWAGYEAKVELAVPMDGRKRFRGILGVPSADGATVPIDLPDVKPGLPSRIDLPLRDLGEAHLVLTDDLIRESLRRGSAPPQDGEDVDEEAGEAPEDEVPQVRFIPQPKRPKPKMDKKSDKKSDKPVKAKKPKPGGGIVTKAARLKNRDTLH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_MAGMM
Sequence: MAEFMWEIGTEEIPARMLPGAITAMGELTRTALQEAGLGFAQVESQGTPRRLLVVVHGLHDKQADVQEERRGPALQAAFDSDGNPTKAAQGFARGCGVDVDQLSRVETPKGTYLSYTLKQAGKGASEVLPGIMQQVFKALPWPKTMRWSDGESRFVRPVQSVTALLNGQQVAVELAENVRYTDAVSGHRFMGKGAVVVQDYASYQQAMADGKVMLKSEDRMATIRAGVLAQAASVGGVVASDEGLVAENASLTEWPVALLGRFDERYLEIPPEVLTTSMRYHQKYFPVLDAQGGLKPHFVVIANMETEDQTVLVRGYQRVLKARLEDAAFFWAEDRKIRLTDRLPDLQAVVWQAKLGSLFQKSQRMAHLASAIAARVAPQQAALAEKAGLYSKCDLVTGMVGEFPELQGIMGGYYLPRERAQDEVVALAIREHYMPAGAGDALPQSLCGRIVSLADKLDTLVGCFGMGITPTGTKDPFGLRRAALGVIRLLLQEQGLRLPLRQLCEEAYRQYGEIGLEMGEAQTVQGVLAFFYGRLQAHLKAEGVDYDLIDAVQGLNLDDLWDAVSRVKALVAFKQDAAYEALVAANKRMANILSKVEDSALDLTLGVDEAVLKASAEQGLAAAVAAVEDRVKTHSSNGRYAEALGELAALRGVIDTFFDEVMVMDEDDAVRHNRLRLLATVLGLFRQVADVSCLVVAEK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAP1B_DANRE
Sequence: MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNSCAFLESSAKSKINVNEIFYDLVRQINRKTPVTGKPRKKSTCQLL
What is the function of this protein?
Probable GTP-binding protein that possesses GTPase activity.  May play a role in endothelial cell polarity and endothelial barrier function (By similarity).
What are the official names of this protein?
Ras-related protein Rap-1b.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol.
Protein: FABZ_BUCA5
Sequence: MNVINNTLNIKKIFKILPHRYPFLLIDRVLNFEKFKYLQAIKNCSINEPYFQGHFSNEPVFPGVLIIESMAQAASILIYKSTGELNINKLYYFVGVDDTRFKKIAIPGDQIFIKVTILKSNKNILIFKNIAVVNNDIICKSKIVFAKKYLF
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STRP1
Sequence: MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKDVTLHLNSLGSPESRAAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLAVEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYSHTIFEFITSVEGSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDIYLAVLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEAGKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_METFK
Sequence: MISKIKELFASFMLLELVKGMALTGRYFFARKVTVQFPEERTPISPRFRGLHALRRYPNGEERCIACKLCEAVCPAMAITIESEQREDNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETRIFDYHGEKRGDLIYTKPMLLAVGDKYEEQIAADRAADARYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: WECG_PECCP
Sequence: MTALKTTETIPLYTIRDLPIHGFRNMAQFVDYLFAGERVETGTLVAINAEKVLTAEKDVALRTLLDRAEYKYADGISIVRSIRRKYPQADVTRIAGADLWEALMERAGKEGTPVFLVGGKPDVLAQTEAKLRAQWNVNIVGSQDGYFAPEQRDALFERIRASGAQFVTVAMGSPRQEILMRDCRHHYPDALYMGVGGTYDVFTGHVKRAPLVWQNLGLEWLYRLLSQPSRIFRQFKLLKYVAYHYSGRL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: ALLA_BRUA4
Sequence: MHVETLVIEPLTKEAFAPFGDVIETEGAELRLINNGTTERYHDLARVEAAGTEARVLVNIFRGQSFEAPIDIVMMERHPFGSQAFIPLNGRPFLVVVAEDDGGKPARLRVFLAHGNQGVNYLRNVWHHPLLALEQKSDFLIVDRAGKEDNLEEFFFSDTTYRIETTKPA
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: COFH_SYNP6
Sequence: MIDSATVAAILASVLDGKPLEPEAATVLLKARDRSLRQQIQAAANQLRSRQVGDRVSYVINRNLNFTNICEQHCNFCAFRRDADQDGAFWLDASILLEKGAAAVAAGATEFCLQGGLNPAAKRNGRSLDFYVELTASLKQAFPQIHLHAFSPQEIQFIAREDGLSFREVLMALRSAGVGSLPGTAAEVLDDSVRRILCPEKLDSATWKTIIQTAHQVGLPTTSTLLSGHLETPSQQAQHLEQLRQLQQAAIAGETPARITEFILLPFVGELAPAPLRKRVKRDQPDLSDALLVMAVARLYLGDWIANHQPSWVKLGLAGATQALDWGCNDLGGTLMEEHITSMAGAQGGTAQTVEQLEAAIAAAGRQPYQRDTLYRPVAVEAVHAG
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: ATPF_YERPP
Sequence: MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQANATDQLKKAKAEAQVIIEQASKRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL6_CHLPD
Sequence: MSRIGKMPIPLSNQAKIEITDTDLTVTGPKGKLHQALTPQVIITQEDGVVTVQRIDDSKKAKAMHGLYRVLISNMVEGVTNGFTRKLEIAGVGYRAELKNDFLALTLGYSHMIYFKAPDEITIQVPDQTTILVTGIDKALVGQVAAKIRSFRKPEPYRGKGIKYEGEVIRRKEGKAAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HYPA_ECOL6
Sequence: MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPLCHGDMLQIVADDGLQIRRIEIDQE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.