PharMolix/UniProtQA huggingface dataset:
Protein: YIDD_RICCK
Sequence: MSKILLLLIRFYQYFISPLLGNNCRFHPTCSEYAKESITLYGSLKGLWRAFKRIIKCQPFYNGTVLYDTEVRCHARKSGNPVKNKEPK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ENO_PARUW
Sequence: MSYIRSVKGREILDSRGNPTVEVELITDQNVMVKASVPSGASTGENEALELRDGDLNYYFGKGVLKAIANINGPIAQILVGEQVYDQERLDRMLIEADGTDNKGHFGANAILGVSLALARAGALTANLPLYRYIGGVHAHLLPCPMMNIINGGAHADNSLDFQEFMIRPVGASTLREAVRWGAEIFHTLKGILKKAGHVTAVGDEGGFAPNLSSNEEALELILLAIEKAGYQPGKQVVLAMDCAASEFYDKTTKQYFEKKKKQKNQVFAERTAEEQIAYLETLCQNYPIDSIEDALAEGDWCGWQRLTERLGRKIQIVGDDIFVTNPKFLEKGIELGVGNAILVKINQIGTLTETLQTIRLAQTNNYACIISHRSGETEDSIIADISVAANTGQIKTGSLSRSDRIAKYNRLLAIEAELESTALYQDSNRFQIF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SOMA_BOVIN
Sequence: MMAAGPRTSLLLAFALLCLPWTQVVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDGTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FXL20_HUMAN
Sequence: MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Role in neural transmission (By similarity).
What are the official names of this protein?
F-box/LRR-repeat protein 20, F-box and leucine-rich repeat protein 20, F-box/LRR-repeat protein 2-like.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_ECO7I
Sequence: MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAIDETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNDSMFNTPPTFAWYLSGLVFKWLKANGGVAAMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C1_SORBI
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFNGSFIFPECILIFGLILLLMIDLTSDQKDRPWFYFISSTSLVISITALLFRWREEPIISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDLRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGLGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRILDIPFYFSSNEWHLLLEILAILSMILGNLLAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVLSIYYYLKIIKLLMTGRNQEITPYVRNYRRSPLRSNNSIELSMTVCVIASTIPGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RNPA_LISMH
Sequence: MKKKYRIKKNDDFQKVFRRGKSFANRQFVVYTLKQEGSTHFRIGLSVSKKIGNAVCRNRIKRYIRQSFHELESQINPENEYIIIARKPAANMDFHEVKKSLIHVLKVGRVLKQKPNNSK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RECR_MARMM
Sequence: MKTASAGPEIERLISLLAKLPGLGPRSARRAALNLLGKKDALMRPLAEALADAADKIRACSECGNMDVSDPCTVCAAPNRLDAAICVVETVGDLWALERAGAFKGRYHVLGGVLSALDGVRPEDLNITKLVERSAREEVSEIVLALNATVDGQTTAHYLADRMAGCNVSITSLARGVPVGGELDYLDDGTLAAAFRSRSTV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RS15_CARHZ
Sequence: MALTQEQKMEIISKYQLHEKDTGSPEVQIAILTERINQLTEHLKVHKKDFHSRRGLLKMVGQRRSLLNYLKRKDFERYRAIVEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ASNA_PECAS
Sequence: MKKQYIEKQQQISFVKSFFSSQLEQLLGLIEVQAPILSRIGDGTQDNLSGTEKAVQVKVKALPDATFEVVHSLAKWKRKTLGAYDFSFGEGIYTHMKALRPDEDRLSPIHSVYVDQWDWERVMEDGERNAEYLKSTVTRIYQGIKATEAAVHQAFGIQPFLPEQIHFVHTETLLKRYPDLDAKGRERAIAKELGAVFLIGIGGKLSSGHSHDVRAPDYDDWTTPGEQELAGLNGDIVVWNPVLNDAFEISSMGIRVDAEALTRQLALTQDEERLKLEWHQALLRGEMPQTIGGGIGQSRLVMLLLQLPHIGQVQCGVWPQPLRESVSGLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_LACH4
Sequence: MAKDYVTGKKTTFGNKRSHAMNSVRRAWKPNLQKVRILVDGKPKRVWVSTKALKSGKVTRA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: FEN_BPT5
Sequence: MSKSWGKFIEEEEAEMASRRNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTDGDWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ
What is the function of this protein?
Catalyzes both the 5'-exonucleolytic and structure-specific endonucleolytic hydrolysis of DNA branched nucleic acid molecules and probably plays a role in viral genome replication (PubMed:9874768, PubMed:15077103, PubMed:10364212).  Active on flap (branched duplex DNA containing a free single-stranded 5'-end), 5'overhangs and pseudo-Y structures (PubMed:9874768, PubMed:15077103, PubMed:10364212).  The substrates require a free, single-stranded 5' end, with endonucleolytic hydrolysis occurring at the junction of double- and single-stranded DNA (PubMed:9874768).  This function may be used for example to trim such branched molecules generated by Okazaki fragments synthesis during replication.
What are the official names of this protein?
Flap endonuclease, FEN, 5'-3' exonuclease, Exodeoxyribonuclease.
Protein: GRCA_HISS2
Sequence: MIKGIQITQAANDNLLNSFWLLDSEKGEARCLAAKAEFVEDQIVAVSELGQIEYRELPVDVAPTIKVEGGQHLNVNVLRRETLEDAVNNPEKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTQSL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: PTSO_VIBCH
Sequence: MPQLSQTVLIQNRLGLHARAAVKLVQLAQSFDAVLTVQSQDGREATADSVMGLLMLESAQGQNVVISAEGSQAEQALQAVCQLIEQKFDEDE
What is the function of this protein?
Component of the phosphoenolpyruvate-dependent nitrogen-metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism.  The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein NPr by enzyme I-Ntr.  Phospho-NPr then transfers it to EIIA-Ntr.  Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins.
What are the official names of this protein?
Phosphocarrier protein NPr, Nitrogen-related HPr.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUS4_GEKJA
Sequence: MAAVSMSVALKQALWGRRAAAVGAVSVSKVPTRLLSTSTWRLAQDQTQDTQLIAVDEKLDITTLTGVPEEHIKTRKVRIFVPARNNMQSGVNNTKKWKMEFDTRERWENPLMGWSSTADPLSNLVLTFSTKEDAVAFAEKNGWSFDVEERKVPKPKSKSYGANFSWNKRTRVSTK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial, Complex I-18 kDa, CI-18 kDa, NADH-ubiquinone oxidoreductase 18 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: UVRC_LACH4
Sequence: MATQLIENKLKLLPEKPGCYLMKDINGTVIYVGKSKNLKNRVRSYFKSKQVGRRAELVREIRDYDIITVSTDKEAFLLEITLIKKYQPYYNVQLKQGTGYPYIEITREHDPQTRLTSIVCKDGGYYFGPYPNVYAAQATLKFIQKVFPLRRCHGYQGRPCLYYHMGQCLGACFKKVPQKEYDEQIKKIKRFLNGDIGAVKQDLTQKMEQASEQLEFERAAEIRDQLKYIEETVEKQKIISNDNTQRDIFNYYVDKSWISIQIFFLRQAKLLRRETRMFPLTDITDPEDAFTSFIVQFYGQKNRVLPKEVLIPAGFDNDTLAEVLTVPVRTPQRGQKKSLLDMAKDNAKLKLDDKFRLLELGNRKTKGAQKEIFDALGLPYGHIIESFDHSHIQGADPVSALVVFKDGEPDKTAYRKYKLKGEVEHQNGGDEVRNTREVVRRRYGRLLREHKKMPDLILMDGGQIQVDACEDVLRNELNLNIPVAGMVKDDKHRTNHLLFGDPINGVPLKLIPLNPKSEGFYLMTRIQDEVHRFAITFHRRRHAKNALSSRLDSIKGIGPKSRNKLLRKFGSLKKIKEASVDDLRAAGLTLPQAQTVKLML
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF104_ARATH
Sequence: MGFSPKTLVAFCWTVLFIISFVHCLPMTHGGKPGYGIERTIIRPEWRCYVDEGCPKGQGAPCEKNCKNVADYGICIGIKCCCFDVIPVPPT
What are the official names of this protein?
Putative defensin-like protein 104.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL35_SALAR
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MNMC_YERE8
Sequence: MSHPPIQTATLSWNEQGTPVSEQFGDIYFSNEDGLEETHYVFLKGNGFPERFALHPRDNCVFAETGFGTGLNFLTLWRDFAQFRQLHPAAKLQRLHYISFEKYPLQVADLAAAHQRWPELACFAEQLRAQWPLPLAGCHRILLAEGAITLDLWFGDVNTLLPQLDSSLNNQVDAWFLDGFAPAKNPDMWNDVLFNAMARMARPGGTFATFTAAGFVRRGLQQAGFDVAKIKGFGQKREMLTGILPQRLNTQSEPWYHRPLATRCDDIAIIGGGIVSALTALALLRRSAKVTLYCADALPAQGASGNRQGALYPLLNGKNDALEIFFTSAFTFARRQYSQLLEQGIRFDHQWCGVSQLAFDEKSRGKINKMLQTDWPPQLAAAMSREQLSALAGLDCAHDGIHYPAGGWLCPSDLTTALMALAQQLGMTCHYGHELCQLERVDGLWQLIFTSPQVNRQHTTVVLATGHRLPEWQQTQHLPLSAVRGQVSHIPTTPVLSQLRQVLCYDGYLTPVNPANQHHCIGASYQRGDVTTDFRADEQQENRDRLLRCLPDVSWPQQVDISDNQARCGVRCAIRDHLPMVGAVPDYSATLAQYQDLPRKIQHGEDIPLAPVWPELFMVGALGSRGLCSAPLVAEILAAQMFGEPQPLDTTTLAALNPNRFWIRKLLKGRPVQQRVSVLS
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPRB_SERMA
Sequence: MELGLEPADDFKEKLIKLSA
What are the official names of this protein?
Uncharacterized protein in proB 5'region.
Protein: RPB1_IIV6
Sequence: MSANNNMESEIKEIESISFGMMSSEDIRQMSSFEVKTAKISSTNLLETVHDPKSGPIGSAPCETCHQNEWDCPGHFGHIELNVPIIHPLFINHVVNILKIFCWKCNEFLLTKDHLELNNILKLEKEKKFNAVLEKIKKCDRCVHCTTPRADYKLVLNDITYKTIYRTFSYQGGAVKTARDKKLNESREIVSAEMVKKIFDNIKLEYVEMLGISHPKDFCLEVFPVIPSCCRPHEVQDGNINDDDLTYQLMEIVKNNSMIGAIKLEKESMEKQYPECLKVKEILLLSNVEKQKKEIDDFLKKPIKNGLKTKKKINKEEITPLDQYLKLHDKYVKYVNNLKFRIETYCNNSQGKATHATTGRAIKGLRERLTGKEGQIRNNLLGKRCEMSARTVIGPDPTLKIDEVIVPKEIAQSLTFPDFVNKHNIDRLTKLVNSGNAIRLVKKNESGQEIKINLAAAINNHGTPLQHDDIIKRPKITNNHEEKHNYEEKHNFDTFETIVIKDPKNFVLKEGDILFRNNFQQKVVLPSKKFIKLEEGWIVHRYLQNGDILVLNRQPTLHKASMMALRVKIMDVKTFKFNLACTKPYNADFDGDEMNAHAPQSEESKAELFTLSTPKQCIMSCQSGKPNLTIVQDSLTGAYLMSKENNNDATLTNGEFNDILMVLTQNDEYNGDVVDYFLKRKEDVSNTLKKLGFSGTVLNGKGLLSLLFPNDLYINEEDLKINRGVIYDGCLTKKYLSSTESSLIKILYKEYGVETCATFLNNIQFLTNRWLMISSFSIHAGDCIKQKEVLGTVEQCLMESEKIKMTTQNPFIREQKIMQTLSNAKDVGMKIAKDALKRDNVNLHAQNNFLTTVESGSKGDHLNIAQITSLLGQQITEGQRVKPLLSNGKRTLPHYILKEENNDTEHFHDLLEEYESQGFISSSFAQGLNPKEFFFHCMAGRQGVCDTAMSTATSGYIMRRNVKLTEDIKVAYDGTVQDTRGRRFQMAYGELGYDPSKLVKVNGKPEVCNIARLVNKLNCNFEDNIK
What is the function of this protein?
Component of the DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Forms the polymerase active center together with the second largest subunit (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase II subunit RPB1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: EGON_DROME
Sequence: MNQLCKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAGCKHNGDCVINKKNRTACKACRLRKCLLVGMSKSGSRYGRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQLARLQQASNQARQTYQDKTNPCIKSATATTSPRIEGAAVGTGIGGGASPSFLQAAKLHHQRQLKLDSRLSNTPSDSGASSAGDPNEDGVTSVLGGQIATPSSTNATSLPKLDLRHPNFPATSEPDADMQRQRHQELLEIFRSHSEPLYSSFAPFSHLPPVLLAAGVPQLPIFKDQFKAELLFPTTSSPELEEPIDLSFRSRADPASPMAHNSNSPSLSEPAAASHCLGESTNFVRKSTPLDLTLVRSQTLTG
What is the function of this protein?
May play a critical role in development of the progeny of eagle-positive neuroblasts.
What are the official names of this protein?
Protein embryonic gonad, Nuclear receptor subfamily 0 group A member 3, Protein eagle, Protein spready.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR0 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KUNPP_ORNKA
Sequence: MQANIFVFAFLLLSVAVAAYGYQPECLEPSLYGCRGDEDATFGWTFDREDGGCRQGSYCTRFGQPKNYFRSERDCKKACGNA
What is the function of this protein?
Tick salivary platelet aggregation inhibitor that plays an important part in the anti-hemostatic strategy of ticks (PubMed:11932256).  Inhibits platelet aggregation induced by ADP (IC(50)=130 nM), collagen, the thrombin receptor-activating peptide, and epinephrine, although platelets are activated and their shape changed (PubMed:11932256).  Binding to platelets is similar for resting and activated platelets (Kd=50-70 nM) (PubMed:15147758).  Acts by specifically binding to platelet membrane glycoprotein IIb-IIIa (ITGA2B/ITGB3) in a divalent metal ion dependent manner (Probable) (PubMed:15147758).  In contrast to many disintegrins which only interacts with the beta-3 subunit, this protein interacts with the two subunits (alpha-IIb and beta-3) (Probable).  Also causes disaggregation of aggregated platelets without influencing the activated spherical shape associated with aggregated platelets and causes a decrease in the number of pseudopodia on the activated platelet surface (PubMed:12593588).  Does not show any inhibitory activity for the different serine proteases tested (PubMed:11932256).
What are the official names of this protein?
Savignygrin (+), Platelet aggregation inhibitor, PAI.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Before secretion, is localized to dense core granule type 'a' and to granule type 'b', but not to granules 'c' or 'd'.
Protein: RR7_PLETE
Sequence: MSRRRTPKKRVIAPDALYNSVLVHTIVNHLMKKGKKSLAYMMFYETLSEIKQKTEQDPLEVIQKAVNNVRPLVIVKSRRVSGSTRQVPLSVDYEIGVALAIRWILAACRKRVGKSMISKMTNEFLDASKNIGNAIRKKDEIAKMAQANRAYARF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPXA_RICFE
Sequence: MSNSNIHPTSLIAEKAKLGKNVKIGPYCIIGPEVVLHDNVELKSHVVIEGITEIGENTVIYPFASIGQPPQILKYANERSNTIIGSNNTIREYVTVQAGSQGGGMVTRVGNNNLFMVGVHIGHDCKIGNNVVFANYVSLAGHIEVGDYAIIGGLSAVHQYARIGEYSMIGGLSPVGADVIPFGLVSSKRAVLEGLNLIGMNRKGFDKADSLSALKAIEEIFSGEGNFAERIKQVAEKYKNNSIVMQIIDFLNQDSSRAFCRFEK
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSA1_ARATH
Sequence: MEIYTMKTNFLVLALSLCILLSSFHEVSCQDDGSGLSNLDLIERDYQDSVNALQGKDDEDQSAKIQSENQNNTTVTDKNTISLSLSDESEVGSVSDESVGRSSLLDQIKLEFEAHHNSINQAGSDGVKAESKDDDEELSAHRQKMLEEIEHEFEAASDSLKQLKTDDVNEGNDEEHSAKRQSLLEEIEREFEAATKELEQLKVNDFTGDKDDEEHSAKRKSMLEAIEREFEAAMEGIEALKVSDSTGSGDDEEQSAKRLSMLEEIEREFEAASKGLEQLRASDSTADNNEEEHAAKGQSLLEEIEREFEAATESLKQLQVDDSTEDKEHFTAAKRQSLLEEIEREFEAATKDLKQLNDFTEGSADDEQSAKRNKMLEDIEREFEAATIGLEQLKANDFSEGNNNEEQSAKRKSMLEEIEREFEAAIGGLKQIKVDDSRNLEEESAKRKIILEEMEREFEEAHSGINAKADKEESAKKQSGSAIPEVLGLGQSGGCSCSKQDEDSSIVIPTKYSIEDILSEESAVQGTETSSLTASLTQLVENHRKEKESLLGHRVLTSPSIASSTSESSATSETVETLRAKLNELRGLTARELVTRKDFGQILITAASFEELSSAPISYISRLAKYRNVIKEGLEASERVHIAQVRAKMLKEVATEKQTAVDTHFATAKKLAQEGDALFVKIFAIKKLLAKLEAEKESVDGKFKETVKELSHLLADASEAYEEYHGAVRKAKDEQAAEEFAKEATQSAEIIWVKFLSSL
What is the function of this protein?
Involved in seedling development in the dark.  May be involved, when interacting with TSK, in the organization of spindle microtubules and may participate, when interacting with GIP1, in structural links between the nuclear envelope and the cytoskeleton.
What are the official names of this protein?
TSK-associating protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Nucleus envelope. Cytoplasm. Note=In interphase, found in ER bodies and at the nuclear envelope (PubMed:24348487). During mitosis, concentrates in limited areas close to the ends of spindle microtubules ahead of separating chromatids (PubMed:15964904).
Protein: CYOC_BUCAP
Sequence: MIKETMRNNKLFGLWIYLMSDCIIFAVLFAVYAIISSNFSTNLINHKIFNLSYVFLETLILLLSSLSSGMLTIQKNKNNIKIIYFYLLLTFFLGLSFLLMEVNEFYKLILENCSPSQHAFFSIFFTIVGVHGIHVFFGLIFILSILYQLFYLGITNTIRIRILCFSLFWHFLDIIWICVFTFVYLNGVI
What is the function of this protein?
Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration.  Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity).
What are the official names of this protein?
Cytochrome bo(3) ubiquinol oxidase subunit 3, Cytochrome o ubiquinol oxidase subunit 3, Cytochrome o subunit 3, Oxidase bo(3) subunit 3, Ubiquinol oxidase polypeptide III, Ubiquinol oxidase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FES1_SCHPO
Sequence: MEKLLAFSTQLQAQGNSSNSPPDPKDLDPSVLDHIFGANPADEMRKAMDAIEDPSVPLDQKEIAFDNLEMLVEHIDNANNLVPLQLWPRLLKQLESPESTLRRLAAWTIATAVQNNPKSQQALIENDGLKILFGALKKEDSDETKNKVLYAITSELKLNEAGIALLDKIPNSWEMLIEILELKHSVMTKRVIFFFYALLIQEDKSKQIILQKAHEFQIPEKVYQFSLEHSVDEDCVTKSLHTLYLFQKNKVSVANTNELLKSLVQFKSEFPEIFTVDEWKAFHEALE
What is the function of this protein?
Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP.  Required for fully efficient Hsp70-mediated folding of proteins (By similarity).
What are the official names of this protein?
Hsp70 nucleotide exchange factor fes1.
What is the protein family that this protein belongs to?
Belongs to the FES1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.