PharMolix/UniProtQA huggingface dataset:
Protein: ATPG_GLUDA
Sequence: MASLKDLRARIGSVKSTRKITSAMKMVAAAKLRRAQGRAEAARPYAAAMRRMLAELGASVRNEAGLPQLLAGTGKDKVHLLIPMTSDRGLAGAFNANINRTTRDLIRRLQAEGKTIRLLPTGRKGYEFLMREFSDLIVDHVHGSGGKEVPFSAAAELGERLTAMLEKGEFDVCTVVYNRFNNVMSQTPTEMQLIPLAVPANDTVASGERASYEFEPGEEQLLSSLLPRNLQVQLYATMLESAAGEQGARMTAMDNATRNAGKAIDRLTLTYNRTRQTNITNELIEIISGAQAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RR4_PATSQ
Sequence: RFKKIRRLGALPGLTSKRPRSGNDLKNQLRSVKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKVKGSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPQDIITTKDKQKSKALIQNYIASSTQPQEELPNHLTIDPFQYKGLVNQIRDSKWIGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THIC_ECODH
Sequence: MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PA2A_PSEAU
Sequence: NLIQFGNMIQCANKGSRPTRHYMDYGCYCGWGGSGTPVDELDRCCQTHDDCYGEAEKKGCYPKLTLYSWDCTGNVPICSPKAECKDFVCACDAEAAKCFAKATYNDANWNIDTKTRC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 PA-1G, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NADA_RHOBA
Sequence: MVDLPTTTPPAQPTTGNDEVDALHPLKPYRSLENEVLQQRIEAVRQELGDELLILGHHYQQDEVIEHTDLRGDSYQLSEMAAKSQACRTIVFCGVHFMAETADILANRPDRIEARDGRRVDVLLPDMAAGCSMADMAAIAQVEAAWADMSEVIDTEQVIPVTYINSAASLKAFCGRHGGIVCTSSNARAVLEWAFERGQRVFFFPDQHLGRNTALTMDITEEQMPVWDPYALEMGGNTDEQIQSSRVILWKGHCSVHQMFRAEHVDRFRKEHPGIKILVHPECPREVNDIADVSGSTGKIIQTIKNSPAGTKWAIGTELHLVNRLKDEHPEQEIHFLSPVVCMCATMYRIDLTHLCWTLENLRDGRLVNQIRVDEETTKWSLIALERMLAVK
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP2_ROTAP
Sequence: MAELACFCYPHLENDSYRFIPFNSLAIKCMLTAKVDKKDQDKFYNSIIYGIAPPPQFKKRYNTSDNSRGMNYETSMFNKVAALICEALNSIKVTQSDVASVLSKIVSVRHLENLVLRRENHQDVLFHSKELLLKSVLIAIGHSKEIETTATAEGGEIVFQNAAFTMWKLTYLEHKLMPILDQNFIEYKITLNEDKPISESHVKELIAELRWQYNKFAVITHGKGHYRVVKYSSVANHADRVYATFKSNNKNGNMIEFNLLDQRIIWQNWYAFTSSMKQGNTLEICKKLLFQKMKRESNPFKGLSTDRKMDEVSQIGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: LZTS1_HUMAN
Sequence: MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGHGKSSSKMGKSEDFFYIKVSQKARGSHHPDYTALSSGDLGGQAGVDFDPSTPPKLMPFSNQLEMGSEKGAVRPTAFKPVLPRSGAILHSSPESASHQLHPAPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTSSSYQLDPLVTPVGPTSRFGGSAHNITQGIVLQDSNMMSLKALSFSDGGSKLGHSNKADKGPSCVRSPISTDECSIQELEQKLLEREGALQKLQRSFEEKELASSLAYEERPRRCRDELEGPEPKGGNKLKQASQKSQRAQQVLHLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTSFGPALEETQWEVCQKSGEISLLKQQLKESQTEVNAKASEILGLKAQLKDTRGKLEGLELRTQDLEGALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELQELRAQAALARDMGPPTFPEDVPALQRELERLRAELREERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYVAMYQRNQRLEKALQQLARGDSAGEPLEVDLEGADIPYEDIIATEI
What is the function of this protein?
Involved in the regulation of cell growth.  May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation.  May act as a tumor suppressor.
What are the official names of this protein?
Leucine zipper putative tumor suppressor 1, F37/esophageal cancer-related gene-coding leucine-zipper motif, Fez1.
What is the protein family that this protein belongs to?
Belongs to the LZTS family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cell projection, dendritic spine. Postsynaptic density. Synapse. Note=Associated with the plasma membrane and with microtubules. Detected in dendritic spines, especially in the postsynaptic density (By similarity).
Protein: THIM_LISMF
Sequence: MFDFMTLEKVWEKGPLVHNITNIVVANDSANGLLAIGASPIMGSAKEEMDELAKMADVLVINIGTLDGELVTAMKIAGRAANVAGTPVVLDPVGVGATSYRRKVVQELLAEIQFTAIRGNAGELAAIAGEAWEAKGVDAGVGSADVLSIAEKVANEWSTVVIISGEVDVISDGTRFAKVANGSALLPRITGSGCLLSAVCGSFMAVQDDAFRASVEACASYAVASEYAEIELERKLPGSFRPQFLDALASWSVEKTRAKAKIQESGEHK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RS21_PROMM
Sequence: MAQVTVGENEGVESALRRFKRAVSKAGIFSDLKRIRHHETPVEKYKRKAQQRRRSRRR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ACER1_DANRE
Sequence: MAGVFSYESSEVDWCEDNYKHSENVVEYFNTMSSFIFFVISPIMLYLLHPYAKERNLAVHLVWIMMVFVGIFSMYFHMTLSFMGQMLDELSILWVLAIGYSLWFPRKHFPSFVKDRTSFARLVLTITIISTLSSFVKPTANAYALNCFAIHILYSLFVELKSCTDERVLRLAWASIGLWVLAISCWISDRFGCSFWQKLDFCYLHGIWHILIVMATAYASTLIAYLDASQEIPYSLPDLQYWPRNNWAIGLPYIVLKGTNTTRKTC
What is the function of this protein?
Endoplasmic reticulum ceramidase that catalyzes the hydrolysis of ceramides into sphingosine and free fatty acids at alkaline pH.  Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation.  May also hydrolyze dihydroceramides to produce dihydrosphingosine.
What are the official names of this protein?
Alkaline ceramidase 1, AlkCDase 1, Alkaline CDase 1, Acylsphingosine deacylase 3, N-acylsphingosine amidohydrolase 3.
What is the protein family that this protein belongs to?
Belongs to the alkaline ceramidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NEU1_HIPAM
Sequence: CYIQNCPLG
What is the function of this protein?
Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.  Acts by binding to oxytocin receptor (OXTR) (By similarity).
What are the official names of this protein?
Oxytocin, Ocytocin.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMM_LACP7
Sequence: MEDLLRVGVISSTHGIKGEVKVFPTTDDMNRFKKLKMVTLDTGKEQKELEIENVKFFKQFVILKFKGIDNINDIEKYKGKDLLISRENAVDLAEGEFFIFDLIGLQAEEEDGNSLGELTEVLQTGANDVFVIKTKQGKEILIPYIDDCVKKIDLNEKKLVVHLIPGLVE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECU_STREM
Sequence: MVNYPHNPIRQKVTPLQKQQKHRQVDFANRGMSFEAAINATNAYYLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAKETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQIDRGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y807_AFV1Y
Sequence: MSAQQQCDLTSYDAMYYLQTGDLQLAVNLFISPNSSFSYSGNSGQSILQSLGTIIIWVYKVNGQIHIYTIGWQPIYYSLQNGCRANIYFRLWALIQIQGAWLASEIMNMPVTLKNTGGQFVGTFIPLHLLGFAIADFPSLSSGSQGYTHMLMSQTDGSIKLLPSAPGVLPYFITVGFQCRAGAYVLKQPCPNCIFVRLCVPTSNGIPYEVLMLICLLIYAGCYASYSDILGKNGLSTVGAGVNAKVPVTAIVYFDTQQYIQQNVVSQLNVTIQLYALIWVGISTTNFVILPEISQILKMPSGLILNIPVPFQAYPTPTVAIPRILTLITCCGTPYIYNQYFPCSFDKASTVTTECGVPLVAYPTISQMQPIAGSNVAFLLSNQSADFADLLSLNYGLLNLTTQQKVSLANQYSYTMTQCKKEVIRGTYYEECVKNVSSNLNQYSSQPASPQPNIPVDEILIGVGAVALIVIGTVALVLTGGASAPVSAGLDVAGAEALGSLLLDNGALSLSSLQEEGLANTLMQTSVSDSFESEDEEIVQNEPNSAKLVVFTNTNQPFTLTVTGTDITGTVTIQSGIADFDLTITLPSGVSVPISVPAGVIDDFTDDQGYTIYEQEDQPVRLKYSDGQVIYNTISQLGKKLDGFFSLLKKLLKYIAVALLSAIASILVNMFLFMPLVASIMTSIIQSGQGVSSGGTVTVTGQSTSTTLSTALSDIASTFGQIPQILEEIPVALASAYLITDLLTDFFGDLWRGFSKNLLPNKAVNVNIPQPLEVDLKSRLKAYSEAVISKNDKGEWVINKKLRGRFS
What are the official names of this protein?
Putative transmembrane protein ORF807.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: SYE2_CAMJD
Sequence: MYRFAPSPTGDMHIGNLRAAIFNYICARQKNMDFILRIEDTDKSRNIKGKEEEIKEILNLFGISWQHYYIQSENLKFHRQMALKLVSEKKAFACFCTEEELEAKKELAKKQGKAYRYDGTCEKLADIDVLECEKSFVIRLKKPTHTMKFTDFIKGELSFEPENIDSFVIMRTDKTPTYNFACAVDDMLENVTCIIRGEDHVSNTPKQEHIRASLGYDKAMTYAHLPIILNEEGVKMSKREAHSSVKWLLESGILPSAITNYLIMLGNKTPYEIFTLEEAIKWFDISKVSKAPARFDLKKLLQINREHIKMIKDDELNKILDLNKDLAQLAKFYTQEASTIKELKEKMRAIFNTKDFGEFETECKILKELLKDIELFENYEDFKNKLLNKSSLKGKKFFMPLRIILTGNIHGPELSDLYPYIKNFIHELARI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_CHLTR
Sequence: MQHTVDIQAIESKLNFTFSHPRLLITALTHPSYRNEFPSAEEDSERLEFLGDAVLGLVVTEHLFLLFPALNEGLLSTTRAALVNAEACFEYTQKLSLGEHLLIGRGEKMQSHRGKISAYANLLEAILGAVYLDGGLSPARQIIVPLLPDKESILPLMLVNPKNRLQQFTQQTLKVLPSYKALPWKSEDGSPGYHVQVFVNGDLWGEGFAGSKKEAEKLAAKQALSTHDNKN
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_BORHD
Sequence: MFKKVESKVNFPKIEEKVLKFWNDNKIFEKSMQQREGCEEFTFYDGPPFATGLPHFGHFVPNTIKDIIPRYKTMKGKHVKRYFGWDTHGLPVEYEVEKSLQISGRYEIEKYGVDKFNEECKNIVLRYTKEWQKTISRLGRWVDFEHNYKTMDTTFMESVWWVFQTLYNKGLIYESYYVLPYSPKLATPLSNFEVNLGEYKEVHDPSLTIKFKIKDKNEYLLAWTTTPWTLPTNLGIAVGRDIDYSKIFDKEKNETFIIGTKRLNHYYKDDKTYTVIEQFKGEHIKGIEYEPVFDYFLSQRNKGAFRIHTAEYVTTDDGTGIVHIAPFGEEDYNILKKNTKTDMITPIDAECRFTNEVKDFEGLFVKDADNKIIEKLKSMNLLFKRENFLHRYPFCYRTNSPLIYRPISSWFVNIEAIKEKLIKSNEQINWIPSHLKKGRFGKWLENARDWAISRNRFWGNPIPVWICSKTGNKICIGSKEELERLSGQKVNDLHKDKIDKITWPSQYGGTYVRTSEVLDCWFESGSMPYASKHYPFKDKDKFHDIFPADFIAEGLDQTRGWFYTLTILGTALFEQTAFKNVIVNGLVLSSDGRKMSKSLRNYTDPMEVINTFGADALRLYLVMSPVVRADDLKYSDDGVKDVLKNIIIPIWNAYSFFITYAIIDKFEPNSNIVLYKTNILDKWIISEIESLKKTLNEEIDKYNLTKSIEELLAFIDKLNNWYIRRSRRRFWKSENDNDKIDAYETLYYALKNLMLMLAPFIPFLTEEIYQNLKTKDEKESIHLNEYPQEIKELINIDLEEKMNFIRKVVSIARALRASHNIKIRKPISTIYIVTKDQKEQQILSEMKEIILEEINSEEIKIKSNEEELVTYKAKANFRELGSKLGTNMKAVALEIMKLNNEDILKIINGNKHTIKIKDNTYDITLKDIILERHEKENLKVINEDSVTIGLDALITEELYLKGLSRELIRKVQNLRKENNFNVSDRIILYIDNNEILKKIISQFESYIKNETLTLKIEINNEKALTKVELDDEILIKIGIEKWSN
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_METAC
Sequence: MEQTYVMVKPDGVQRGLVGEVISRIEKRGLKILALRMNVIAEATAKEHYGEHAARPFFPSLIEFITSGPSVSMVVAGKDAIKVMRAINGATNPVDAAPGTIRGDFALDVGRNVVHASDSPEAAAREIAIHFKDSEIGKYSRVDEVCLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK2_PARMW
Sequence: MGKVVGIDLGTTNSCVSVMEGGKPTVIANAEGFRTTPSVVAYTKNQDQLVGQIAKRQAVMNPDNTFYSVKRFIGRRVDEVNEESKEVSYGVEKAGSNVKVKCPVLDKQFAPEEVSAQVLRKLAEDAGKYLGETVTQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKKSNERILVFDLGGGTFDVSVLEVGDGVFEVLSTSGDTHLGGDDFDKVIVDHLAETFKSNEGIDLRQDKQALQRLTEAAEKAKIELSSATQSEINLPFITATPEGPKHLDLTLTRAKFEELAANLIDRCRIPVEQALKDAKLSSSELDEIVMVGGSTRIPAVLELVKRTTSKDPNQTVNPDEVVAVGAAIQGGVLAGEVKDILLLDVTPLSLGVETLGGVMTKMITRNTTVPTKKTETYSTAVDGQTNVEIHVLQGEREMASDNKSLGTFRLDGIPPAPRGVPQIEVTFDIDANGILSVTAKDKGSGKEQSISITGASTLSDSEVDKMVKDAEANASADKEKREKIDLKNQAETLVYQAEKQMGELGDKVEADAKAKVDEKRTKLQEAINAEDYDAMKTLLEELQQELYTVGASVYQQEGAAAGGAAPGGDAGASAASGGGDASDDVIDAEFTETK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK2, HSP70-2, Heat shock 70 kDa protein 2, Heat shock protein 70-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CAD1_MEDTR
Sequence: MGSIEVAERTTVGLAAKDPSGILTPYTYTLRNTGPDDVYIKIHYCGVCHSDLHQIKNDLGMSNYPMVPGHEVVGEVLEVGSNVTRFKVGEIVGVGLLVGCCKSCRACDSEIEQYCNKKIWSYNDVYTDGKITQGGFAESTVVEQKFVVKIPEGLAPEQVAPLLCAGVTVYSPLSHFGLKTPGLRGGILGLGGVGHMGVKVAKAFGHHVTVISSSDKKKKEALEDLGADSYLVSSDTVGMQEAADSLDYIIDTVPVGHPLEPYLSLLKIDGKLILMGVINTPLQFVTPMVMLGRKSITGSFVGSVKETEEMLEFWKEKGLSSMIEIVTMDYINKAFERLEKNDVRYRFVVDVKGSKFED
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers.  Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols (By similarity).  Can use coumaraldehyde and, with a lower efficiency, coniferaldehyde and sinapaldehyde as substrates (PubMed:25217505).
What are the official names of this protein?
Cinnamyl alcohol dehydrogenase 1, Mt-CAD1, Coniferol dehydrogenase, Coumaroyl alcohol dehydrogenase, Sinapyl alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: MTAP_MYCTU
Sequence: MHNNGRMLGVIGGSGFYTFFGSDTRTVNSDTPYGQPSAPITIGTIGVHDVAFLPRHGAHHQYSAHAVPYRANMWALRALGVRRVFGPCAVGSLDPELEPGAVVVPDQLVDRTSGRADTYFDFGGVHAAFADPYCPTLRAAVTGLPGVVDGGTMVVIQGPRFSTRAESQWFAAAGCNLVNMTGYPEAVLARELELCYAAIALVTDVDAGVAAGDGVKAADVFAAFGENIELLKRLVRAAIDRVADERTCTHCQHHAGVPLPFELP
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Prefers MTA, with 2% activity on adenosine, 0. 8% activity on S-adenosyl-L-homocysteine and no activity on other tested nucleosides.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: APPC_BACSU
Sequence: MSELQTTPSPEIRLKENISKKPETMTKIFWEKFSKNKLAILGAVILFIIIMSAVFAPLIAPYPQEQQSLLDKYKAPGLEHLMGTDKFGRDIFSRILYGARVSLLVGFASVVGSILIGTVLGALAGYFRGIVDAVIMRVVDIVLSIPDIFLLITLVTIFKPGVDKLILIFCLTGWTTTARLVRGEFLSLRSREYVLAAKTIGTKTHKIIFSHILPNALGPIIVSATLKVGSVILAESALSYLGFGIQPPIASWGNMLQDAQNFTVMIQAWWYPLFPGLFILMTVLCFNFVGDGLRDALDPKNIK
What is the function of this protein?
This protein is a component of an oligopeptide permease, a binding protein-dependent transport system.  This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Oligopeptide transport system permease protein AppC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRDI_BRUME
Sequence: MSLIVYFSSRSGNTHRFVERLGVRSSRIPLEASGALQVREPFVLVTPTYGGGSTKGAVPNPVIRFLNDADNRALIRGVIAAGNSNFGEAFCIAGNIISAKCGVPYLYRFELLGTAEDVGNVRNGMEQFWTRQTQA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: DNAI4_HUMAN
Sequence: MTPGKHSGASARAANGGAWGYRDFRGGQKKGWCTTPQLVATMPVSPAGSHKQQNFGLNNATQPKKSISFFATMKATSVKGYTGANQSRMAVSKTVLIPPELKTVEKPNPNIKTTQVFDINGTDVTPRPLYHPDPLTGTAKPSKLLTSQEGSLGSEFISSYSLYQNTINPSTLGQFTRSVLGSSTVSKSSVSASESIAEDLEEPSYKRERLTSFTDLQVIRAAPEKIVTKEDLEKNIEIILTETETLRFFDLPTVMVSVESEEAEKVTQRNKNYEVLCRNRLGNDLYVERMMQTFNGAPKNKDVQCDKIIMEDKGIMSTAWDLYDSYNAMELVSLSVKQSVVESSSKANVLPKDQDQRLPGSTTEKNSETSSLMDIENVILAKIHEDEEDHSDAILKSDKFHQDLFFMERVLMENIFQPKLAAYRQLPVLKEPEPEEPEDVLESAKHEEVEEESKKEEEEEIHAEESTIPANLERLWSFSCDLTKGLNVSSLAWNKTNPDLLAVGYGHFGFKEQKRGLACCWSIKNPMWPERIYQSPYGVTAVDFSIGAPNLLAVGYHNGTIAIYNVRSNSNVPVLDSSESPQKHLGPVWQLQWIEQDRGTTGDGKREILVSISADGRISKWVIRKGLDCYDLMRLKRTTAASNKKGGEKEKKDEALISRQAPGMCFAFHPKDTNIYLAGTEEGHIHKCSCSYNEQYLDTYRGHKGPVYKVTWNPFCHDVFLSCSADWGVIIWQQENVKPSLSFYPATSVVYDVAWSPKSSYIFAAANENRVEIWDLHISTLDPLIVNTANPGIKFTTILFAKQTDCLLVGDSDGQVSVYELRNMPTVLETGRGDIMDTLLGSKSNQSA
What is the function of this protein?
Plays a critical role in the assembly of axonemal dynein complex, thereby playing a role in ciliary motility.
What are the official names of this protein?
Dynein axonemal intermediate chain 4, WD repeat-containing protein 78.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium axoneme. Dynein axonemal particle.
Protein: RUVC_ECOL5
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.