PharMolix/UniProtQA huggingface dataset:
Protein: LIP2_STAAW
Sequence: MLRGQEERKYSIRKYSIGVVSVLAATMFVVSSHEAQASEKTPTNAAVQKETLNQPGEQGNAITSHQMQSGKQLDDMHKENGKSGTVTEGKDTLQLSKYQSTQNSKTIRTQNDNQVKQDSERQGSKQSHQNNATNNTERQNDQVQNTHHAERNGSQSTTSQSNDVDKSQPSIPAQKVLPNHDKAAPTSTTPPSNDKTAPKSTKAQDATTDKHPNQQDTHQPAHQIIDAKQDDTVRQSEQKPQVGDLSKHIDGQNSPEKPTDKNTDNKQLIKDALQAPKTRSTTNAAADAKKVRPLKANQVQPLNKYPVVFVHGFLGLVGDNAPALYPNYWGGNKFKVIEELRKQGYNVHQASVSAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYKGIMPNWEPGKKVHLVGHSMGGQTIRLMEEFLRNGNKEEIAYHKAHGGEISPLFTGGHNNMVASITTLATPHNGSQAADKFGNTEAVRKIMFALNRFMGNKYSNIDLGLTQWGFKQLPNESYIDYIKRVSKSKIWTSDDNAAYDLTLDGSAKLNNMTSMNPNITYTTYTGVSSHTGPLGYENPDLGTFFLMDTTSRIIGHDAREEWRKNDGVVPVISSLHPSNQPFVNVTNDEPATRRGIWQVKPIIQGWDHVDFIGVDFLDFKRKGAELANFYTGIINDLLRVEATESKGTQLKAS
What are the official names of this protein?
Lipase 2, Glycerol ester hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSN_ECO81
Sequence: MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: QUEF_BACC4
Sequence: MTGRLDEDLKDVTLLGNQNTKYLFEYSPEILEVFDNNHPNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPEQKMVESKSLKLYLFSFRNHGDFHEDCMNVIMNDLIKLMDPRYIEVWGKFTPRGGISIDPYCNYGRPGTKYEQMADYRMMNHDLYPETIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDC3_DANRE
Sequence: MALDWVGNLVSIHCGPTLGVYQGEISSVDQTSQTISLRNPFHNGVKCTVPEVTFSAMDIKDLKILEISKNSIEVSKQNGPESSSTTLMPHVGRKDKGGGGGGGGAPANSAPVMVPNKAEPRLQEGGVSPVPHYSKSYGERHIDMAVQGKGFRRRHNSWSSSCRGPNQATPKKNGLKNGGHMKNKDDECFGDGMDDVLDEDFDFEGNLALFDKAAVLSQIESSERRGNGARSRGTPGEQTPSRYRHDENILEAKPVVYRQITVPQNGSKEYSTDSGLVVPSISFELHKRLLAAAESHGLSLERRLEMTGVCASQMALTLLGGPNRLTPKNVHQRPTVALLCGPHVQGAQGISCGRHLANHEVEVVLFLPNFVKMLEAITSELALFGKTGGRLVSNVKDLPETPVDLVINCLDSHENGFLRDQPWYKAAADWANQNRAPVLSIDPPVSGQAHAVEAKWSLSLGLPLPLSEGAGRVYPCDIGIPRQVFQEVGIKYHSPFGCKFVIPLHSE
What is the function of this protein?
Binds single-stranded RNA.  Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity).
What are the official names of this protein?
Enhancer of mRNA-decapping protein 3, LSM16 protein homolog, YjeF domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDC3 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Processing bodies (PB).
Protein: UVRY_ECOL6
Sequence: MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLMITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
What is the function of this protein?
Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system.  UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop.  Mediates the effects of CsrA on csrB RNA by BarA-dependent and BarA-independent mechanisms (By similarity).
What are the official names of this protein?
Response regulator UvrY.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROP_CORGL
Sequence: MSPIRSKKKIKNEPRLTVDDVNVVPPKKIRPAIKGTVVGNFMEWYDFGIYGYLTVTMTAVFTQGLPQEWQLLAVMFGFAVSYLVRPLGGLVLGPLGDKVGRQKVLYVTMAMMAVSTALIGLLPTAASIGAWALVLLYLLKMVQGFSTGGEYAGATTYVAEFAPDRRRGFFGAFLDMGSYLGFAAGASVVAITTWVTTHFYGATAMEDFGWRIPFLTAIPLGIIAVYLRTRIPETPAFENNQDEPNAVVEKDTEDPYARLGLAGVIRHHWRPLLIGIAIVAATNTAGYALTSYMPVYLEEQIGLHSASAAAVTVPILVVMSLLLPFVGMWSDRVGRKPVYATAVAATLILMVPAFLIMNTGTIGAVLIALSMVAIPTGLYVALSASALPALFPTASRFSGMGISYNISVSLFGGTTPLITQFLLQKTGLDIVPALYIMFFSAIAGVALLFMTESSQKPLLGSFPTVETKSEAVEIVKNQDEDPNIDLSHMPFPDEENVGAEKQNA
What is the function of this protein?
Involved in the uptake of osmoprotectants.  Can transport ectoine and proline.  Protons are probably the coupling ions.
What are the official names of this protein?
Ectoine/proline transporter ProP.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RISB_ACTSZ
Sequence: MKILEGKLAAPEAKIAVVVARFNHFINDSLVDGAVDALKRVGEVKDENITLVKVPGAYELPLAVRRLADTQKFDAIVALGTVIRGGTAHFEYVAGEASSGLGNVSLNADIPVAFGVLTTENIEQAIERAGTKAGNKGAEAAMVALEMVNLLNQIKAA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ENO_CHESB
Sequence: MTAIVDIVGREILDSRGNPTVEVDVVLEDGSIGRAAVPSGASTGAHEAVELRDGGPRYLGKGVARAVEAVNGEIFEAIGGLEAEDQIHIDRTMIELDGTPNKSRLGANAILGVSLAVAKATAAASGLPLYRYVGGASAHILPVPMMNILNGGAHADNPIDFQEFMIMPVGAPTLRDAVRWGSEIFHTLKSGLKAAGHNTNVGDEGGFAPNLKDANAALDFIMASIEKAGFKPGDEVAIALDCAATEFFKDGKYVYEGEGQTRDAQAQAEYLSKLAGEYPIISIEDGMAEDDFEGWKALTDLAGSKVQLVGDDLFVTNAARLKDGINMGIANSILVKVNQIGSLTETLEAVETAHKAAYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEQLGRAARYAGRTVVRG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ALR_MYCVP
Sequence: MTTTPTMTQKLPQALPTASIDLDAIAHNVAVLREHAGPAAVMAVVKADGYGHGATQVARAALAAGAAELGVATVGEALALRRDGVTARVLAWLHPPGTDFAPALLADVDVAVSSLRQFTDLLDAAGRTGRTADVTVKADTGLSRNGVGEADYPALVDALRRAASDGAVRVRGLMSHLAHGDDPEHPFNDVQARRLTEMAKLAGARGVSYDVVHLSNSPAALTRPDLAFDMVRPGIAVYGQTPIPQRGDFGLRPAMTVKCPVSAVRPVRAGDAVSYGHTWTAQTDTTLALVPAGYADGVFRALSNRFEVSINGRRYPNVGRICMDQFVVDLGPGPVDVAEGDDAILFGPGTDGEPTAQDWAELLDTINYEVVTSPRGRIVRTYVGGKGGPQ
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PLSY2_DEHMC
Sequence: MNSLIMVIIALIAAYFIGSTPAPYLAGRIFKKIDIRTVGSKNMGSMNVFYNVGFWPGILVLTTDIGKGALAMAVANWLGEGLGIQMLCALMAIAGHNYPVWLKFKGGKGGATAIGILAYMMPEGIPIYIACFLILMAITRFPTLSYGISFISFILVAWLGQHDMGKVLFSLLVVMIPILMYIPRMKEIKNKAGSGNAKRAIFRRNLKERL
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 2, Acyl-PO4 G3P acyltransferase 2, Acyl-phosphate--glycerol-3-phosphate acyltransferase 2, G3P acyltransferase 2, GPAT 2, Lysophosphatidic acid synthase 2, LPA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VIF_FIVSD
Sequence: MSDEDWQVSRRLFAVLQGGVYNAMLYISRLPQDEREKYKKDFKKRLLDTETGFIKRLRKAEGIKWSFHTRDYHVGYVREMVAGPTTPHSLRLYVYISNPLWHSQYRPGLVNFNKEWPFVNLWIKTGFMWDDIEKQNICIGGEVSPGWGPGMIGIAIKAFSCGERKIEATPVMIIRGEINPKKWCGDCWNLMCLRNSPPETLQRLAMLACGVQAKSWRGCCNQRFVSPYRTPADLEVIQSKPGWCMLWRGKL
What is the function of this protein?
Determines virus infectivity.
What are the official names of this protein?
Virion infectivity factor.
What is the protein family that this protein belongs to?
Belongs to the feline lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: RECO_AROAE
Sequence: MSQKQRIDQQPAFVLHTYPWRETSLVVEIFSRDHGRVALVAKGARRPMSALRGVIMAFQPLLMDWSGGGEVKTLVRAEWRGGQPLLTGRALMCGYYLNELLVRLTAREDAHPALFEAYADALSQLGRGDVAPILRRFELTLLRELGYGIGLDLEGDSNRPVDPVQQYVYIIEKGPVRLAGDDEGLPGVSGQTLLDMAHGDFSRAETLFQSKALLRLLINHYLGGQPLQSRRVLKELQEL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: GLPK_BOVIN
Sequence: MASAKKAVLGPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILQSVYECIEKTCEKLGQLNIDISNIKAIGVSNQRETTVVWDKLTGEPLYNAVVWLDLRTQSTVESLSKRIPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEDRALFGTIDSWLIWSLTGGASGGVHCTDVTNASRTMLFNIHSLEWDKELCEFFEIPMKILPNVRSSSEIYGLMKISHSPKAGALEGVPISGCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKLGRDKPVYYALEGSVAIAGAVIRWLRDNLGIIKSSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCGIPLSHLQVDGGMTNNKILMQLQADILYIPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPEDLSAVTMERFEPQINAEESEIRYSTWKKAVMKSMGWVTTQSSESGDPSIFCSLPLGFFIVSSVVMLIGARYLSGMP
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.
What are the official names of this protein?
Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Bound to the mitochondrial surface or cytoplasmic.
Protein: RS8_METMJ
Sequence: MARLNPIADAMSTIKNAGDAGKGEVIVEPASKLLGAMLRVMQENGFISGFEFIDDGRGGQFRVQLSGTINKCGAISPRFPVAMADMEYWESQYLPAKNFGILIVSTSKGVISHAEARNEGIGGQLLGYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ISL1_RAT
Sequence: MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
What is the function of this protein?
DNA-binding transcriptional activator.  Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes.  Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation.  Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina.  Involved in the specification of motor neurons in cooperation with LHX3 and LDB1 (By similarity).  Binds to insulin gene enhancer sequences (PubMed:1691825).  Essential for heart development.  Marker of one progenitor cell population that give rise to the outflow tract, right ventricle, a subset of left ventricular cells, and a large number of atrial cells as well, its function is required for these progenitors to contribute to the heart.  Controls the expression of FGF and BMP growth factors in this cell population and is required for proliferation and survival of cells within pharyngeal foregut endoderm and adjacent splanchnic mesoderm as well as for migration of cardiac progenitors into the heart (By similarity).
What are the official names of this protein?
Insulin gene enhancer protein ISL-1, Islet-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y394_METAC
Sequence: MEKMTILETTDLKYTYPDGTLAIEDVSISIEKGKKIALVGPNGSGKSTLFLLLNGTLKPQEGEIIFHGKPLLYEKASLRDVRKSVGIVFQNSDDQIFAPTVYQDVAFGPINLEMPEEEVAAKVNETLEYVGLLELKDKPPHHLSGGQKKKVAIAGVVVMEPEVIILDEPLTSLDPVGADEILDLLNELNQFEKAIVISTHDIDFAYSWADYIYLLVNRKIIGSGTPEEIFRDPGMLKDAGLRIPMVLEIYYEIQKRNMASVNRVPKTVPEIVDTLKPPSLIWLDVPEGVKEGDKLDLGLYAEQLGEICSEGVVDTRVLHIHESGQAIVAVKRIRAGIGRVLIYDTDNYKLKEIKGLLASGDFDVVGAMGKKTKLIVESDNLKPDLTVGVIDKSILTALCGKNVLIFTGGGMVDHAVRRISDYCKKSGVRINVDVFNRETGEAQD
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein MA_0394.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SUC2_ARATH
Sequence: MVSHPMEKAANGASALETQTGELDQPERLRKIISVSSIAAGVQFGWALQLSLLTPYVQLLGIPHKWASLIWLCGPISGMLVQPIVGYHSDRCTSRFGRRRPFIVAGAGLVTVAVFLIGYAADIGHSMGDQLDKPPKTRAIAIFALGFWILDVANNTLQGPCRAFLADLSAGNAKKTRTANAFFSFFMAVGNVLGYAAGSYRNLYKVVPFTMTESCDLYCANLKTCFFLSITLLLIVTFVSLCYVKEKPWTPEPTADGKASNVPFFGEIFGAFKELKRPMWMLLIVTALNWIAWFPFLLFDTDWMGREVYGGNSDATATAASKKLYNDGVRAGALGLMLNAIVLGFMSLGVEWIGRKLGGAKRLWGIVNFILAICLAMTVVVTKQAENHRRDHGGAKTGPPGNVTAGALTLFAILGIPQAITFSIPFALASIFSTNSGAGQGLSLGVLNLAIVVPQMVISVGGGPFDELFGGGNIPAFVLGAIAAAVSGVLALTVLPSPPPDAPAFKATMGFH
What is the function of this protein?
Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system).  Can also transport other glucosides such as maltose, arbutin (hydroquinone-beta-D-glucoside), salicin (2-(hydroxymethyl)phenyl-beta-D-glucoside), alpha-phenylglucoside, beta-phenylglucoside, alpha-paranitrophenylglucoside, beta-paranitrophenylglucoside, and paranitrophenyl-beta-thioglucoside.  May also transport biotin.  Required for apoplastic phloem sucrose loading in source tissues (e. g.  leaves) in order to transport it to sink tissues (e. g.  roots, flowers).
What are the official names of this protein?
Sucrose transport protein SUC2, AtSUC2, Sucrose permease 2, Sucrose transporter 1, Sucrose-proton symporter 2.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NHAA_YERPP
Sequence: MTNIIRQFLRQEAAGGLILIIAAAIALLMANSALQGVYQSFLDIPVSIKIASLDISKPLLLWINDGLMAVFFLMIGLEVKRELMEGSLAGRDKAVFPAIAALGGMLAPALIYLLFNGADEVTRQGWAIPAATDIAFALGVMALLGNRVPTGLKVFLLALAIIDDLGVIIIIALFYTQQVSLQSLGIAAAAIALLAYMNWRGVGKTSAYLLVGLVLWVCILKSGVHATLAGVIVGFMIPLHTQDQRSPSESLEHGLHPWVAYLILPLFAFANAGVSLQGVSLSGLTSLLPMGIATGLFIGKPLGIFTFSWLAVKLGIAKLPDAINFKQIFAVSVLCGIGFTMSIFIASLAFEGTDIALTTYSKLGILLGSTTAAVVGYSLLRLVLPARRKAVNVR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YL294_YEAST
Sequence: MMLRKPKKVIELFIASSLSKKKQTEPQAEQDHYFWLSSSHLFIFESSTIKKKQNTLRTLCNQPHKMQNLFFKQKIQLYIDTSLSFLLLLFFYFNNYYFLSMTYASLVNK
What are the official names of this protein?
Putative uncharacterized protein YLR294C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GMHA_HAEIE
Sequence: MYLDQIKAELVEAQDLLNKFISDENNIKLIQEAALLISNSFKQGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDASHLSCVSNDFGYEYVFSRYVEAVGQKGDVLFGLSTSGNSKNILNAIEAAKTKGMKVIAMTGKDGGKMAGLADVEIRIPHFRYADRIQEIHIKVIHILMMLIEFEMAKQA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PESC_DROPS
Sequence: MRRPKKYEAGEATQYISRRAAIRKLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSEIKILYHTKDIRFLLHESIVWTLRDYKIFAKKTSRDRAIKDFRNLKRRLALFPEIKLDHIVKERYPTFIDALKDLDDCLTLLFLFSTFPSLHLIPREQSNLCRRLTIEFLHYVIASKSLRKVFISIKGYYFQAEIKGQKVTWIMPHYYPFKPQSRQEVDFKVMSIFVEFYTILQGFTNFRLFHGLNLAYPPQFPSSLLQDNEDTFKDEASFVSDRIAALNFELLRTDKVQEDEEEPDIDMELLEQDGDSKRIIKMKQEAQEVSRLRTLFKGLKFFINREVPREPLVILIRSFGGKVSWDASVFPGATFAENDETITHQIVDRPSLSTQYISRDYIQPQWLFDCVNQRQLLPTNDYFLGETLPPHLSPFVDSKRDSYIPPEEKALHDPSLIETHEQSEEESEEDEAEKEEEEADQELLDAQLQLAYQQETAEYKKYGGPDGVNEDEEDLSEEDDEEDDDEEDVDKEDVDEQTKRKQQEKEKMSVQSGKVHKVNKRQVHKAEVDEHRLQARMVKPRHRNLFRKLIREKQTKEKEEWLLRKKRRNIDADNKEAKKAAKREARKQAAEAAARAAKLVK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: RS11_DESVH
Sequence: MARPKRTVKKREKKNVPVGLAHIQATFNNTIVTFTDTRGNTISWASAGQSGFKGSRKSTPFAAQMAAEQAAKKAQENGMRTVGIYVKGPGSGREAAMRAINAAGFKVAFIRDITPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RL25_DICNV
Sequence: MAEQKYRYTLHAVVREEQGKGASRRLRRQGLVPAIIYGGNTEPQAIAIKQDELKKNAKNHSFFSQIINLKIDGQEDQEILVRDVQHHIYKPLFQHFDFQRIVRGQEITATVLLEFVGEERAPGIKTDGGIVSRHMTTVEVICRPSLLPEYIAVDLSEANIGDIITLADLKLPEGVRLVGDMEDEEFAATVVVQISYPQREEQMEDTDTAAADEEGDKEEDADKQE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PNCB_VIBVY
Sequence: MCAPLFQPAIIQSVLDLDVYKINMMQAAYRFYPQTQVRYELIVRSDDNLSDLVEEVREEINRLAELRFDAAQLAYLAEKAPYLTAEFLSYLETFRFHPQQQVSVGIFRTAQGDCQLRVTINGIWHETILYETLVMSIISELRNRRYWAQIPQSQLHKVLEDKLDFLDSELKRRNITNFRFSEMGTRRRFSFAAQKTMLDVLRARVPELLLGTSNYHLAQEFNLTPIGTVAHEWTMAHQALVAVQHSQCVALDKWLEAFNGSLGIALTDTIGIDAFLSDFDLEKATAYAGVRHDSGSPFVWGDKIIAHYESLGIDPSTKTLIFTDGLDFARALDICEYFAGRAQISFGIGTFLANDMGNWTNDKGIRYQPISMVVKMAECNGSPVAKISDEPEKAMCEDIFFLMNLKQRFGLEVDLDKAIETLKQMKRQQKKRIQSVA
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: PTH_MYCBT
Sequence: MAEPLLVVGLGNPGANYARTRHNLGFVVADLLAARLGAKFKAHKRSGAEVATGRSAGRSLVLAKPRCYMNESGRQIGPLAKFYSVAPANIIVIHDDLDLEFGRIRLKIGGGEGGHNGLRSVVAALGTKDFQRVRIGIGRPPGRKDPAAFVLENFTPAERAEVPTICEQAADATELLIEQGMEPAQNRVHAW
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHO_MYCTU
Sequence: MTDTDLITAGESTDGKPSDAAATDPPDLNADEPAGSLATMVLPELRALANRAGVKGTSGMRKNELIAAIEEIRRQANGAPAVDRSAQEHDKGDRPPSSEAPATQGEQTPTEQIDSQSQQVRPERRSATREAGPSGSGERAGTAADDTDNRQGGQQDAKTEERGTDAGGDQGGDQQASGGQQARGDEDGEARQGRRGRRFRDRRRRGERSGDGAEAELREDDVVQPVAGILDVLDNYAFVRTSGYLPGPHDVYVSMNMVRKNGMRRGDAVTGAVRVPKEGEQPNQRQKFNPLVRLDSINGGSVEDAKKRPEFGKLTPLYPNQRLRLETSTERLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITRNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLSPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKTTPGSMDSD
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.  Shows poor RNA-dependent ATP hydrolysis and inefficient DNA-RNA unwinding activities, but exhibits robust and fast transcription termination, which suggests that the transcription termination function of M. tuberculosis Rho is not correlated with its helicase/translocase activities and that these functions may not be important for its RNA release process.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: RL10_HELPY
Sequence: MQKQHQRQHKVELVANLKSQFADAKALLICDYKGLSVRKLEALRNKARNQGIKVQVIKNTLAHIAMKETGYSDLDLKETNVFLWGGDQIALSKLVFDFQKEHKDHFVLKAGLFDKESVSVAHVEAVSKLPSKEELMGMLLSVWTAPARYFVTGLDNLRKAKEEN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.