PharMolix/UniProtQA huggingface dataset:
Protein: OPDJ_PENO1
Sequence: MKPNKPRYIACSHCSKAKARCDRKVPCSRCVSKQLVCHPRSARRAIHTPTEQHLRWLEPGDVPRRDEQQTILLAQQTPVDADNTMVTGTHMRPDSPDVSSQLQSTGASYISADKMTHLSTEWLHQITPESSMHMPLNVPLDQDVTHQSSPDLDLINELIGYPACDDLGTTYMEFVGIGPTDSPPLSPSRDGRSVKDRNSRLVALCPGHPRHWSEDFSSQMRISMQRFEQTINLRQPWTTSCSETWASLPYPSVMNPITETTRDSLVAVSQLLLLQTRSIHLWENGRNSRRLSSGNLAVLNLPPAKVLDSLLRAYTSCFDQYFGLLSSELQDPNDIMTHPEHDLKAAGILLLLMIAIGATANPEPKMHIFAIGMAEMCRTALCDLMEDEVPNTRPDILSHCALLLLYLGMWSGERWLMRIICAHRQIYTQLLHRCPLSFNTNDSLQKLHGGLNLSQQWQHWKEQEMQSRLTYAWMVTDQEWSLVYDTPSNFSVDMMTQSLPNSERLWRATSEGDWAALAPEMFGTQAPTCLRDLYTSFMNHELRPGRSTLPLQYLRLLLVPLHGMVFHLRQWLQSFPNCPVRWRKNNQGLSNPAIHAQLDQVQALLPEWYDLAIHLTNTSPAFVSMLVMYHLIALNAMASFPNIEDALLRGPLDRSQLPNPRGSDPCPLGTCQSTVAEDSAEEALVHCGQILRLVRLMPPSDQPLWWSAVVYRIALITIFLSIKRHPHHWLPAVMLGQMVQDTASSSGTSTDGSGVSLMSNPLFTDRVDAQPHHRPVILNNVAPNDNELLQFTKYREGEPCLAVRDGQLIELRQPRDVMSFFIDLVDGGHLPALHATNFQASVKDSLERLADRWGFLSLHKT
What is the function of this protein?
Transciption factor that positively regulates the gene cluster that mediates the biosynthesis of oxopyrrolidines, polyketide-amino acid hybrid compounds with feature structures of tetramic acid.
What are the official names of this protein?
Transcription factor opdJ, Oxopyrrolidines biosynthesis cluster protein J.
Protein: M370_ARATH
Sequence: MVFQSFILGNLVYLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRARVMDEGEEGTEKKVSATTGFIAGQLMMFISIYYAPLHLALGRPHTITVLALPYLLFHFFFWNNHKHFFDYGSTTRNEMRNLRIQCVFPNNLIFKLFNHLILPSSMLARLVNIYMFRCNNKMLFVTSSFVVCVRMLLVEWAFPLFQLFLVMKV
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00370, ORF199.
What is the protein family that this protein belongs to?
Belongs to the ycf1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: DPOL_HPBDW
Sequence: MPQPLKQSLDQSKWLREAEKHLRELENLVDSNLEEEKLKPHLSMGEDVQSPGKGEPLHPNVRAPLSHVVRAATIDLPRLGNKLPAKHHLGKLSGLYQMKGCSFNPEWKVPDISDTHFDLQVINECPSRNWKYLTPAKFWPKSISYFPVQAGVKAKYPDNVMQHEAIVGKYLNRLYEAGILYKRISKHLVTFKGKPYHWELQYLVKQHQVPDGTTTCKINGREENRRRRAPAKSISRPHDTERNCHMVGQVSNNRSPIRSCANNGGGKYSSTTRRMACWGGQTIGVNQSCSPRTSAASVDAGRRSKSSRGLSSLSRRETTGNHHHSTNVTNSVEAATRGRSPAGKQVSARDTSSLPESGASRACDKNSSPQKEENGWYLRGNTSWPNRITGRLFLVDKNSRNTTEARLVVDFSQFSKGKNAMRFPRYWSPNLSTLRRILPVGMPRISLDLSQAFYHLPLNPASSSRLAVSDGQHVYYFRKAPMGVGLSPFLLHLFTTALGSEIARRFNVWTFTYMDDFLLCHPNARHLNSISHAVCTFLQELGIRINFDKTTPSPVNDIRFLGYQIDQKFMRIEESRWKELRTVIKKIKIGAWYDWKCIQRFVGHLNFVLPFTKGNIEMLKPMYAAITNKVNFSFSSAYRTLLYKLTMGVCKLTIRPKSSVPLPRVATDATPTHGAISHITGGSAVLAFSKVRDIHIQELLMVCLAKIMIKPRCILSDSTFVCYKRYHTLPWHFAMLAKQLLSPIQLYFVPSKYNPADGPSRHKPPDWTALTYTPLSKAIYIPHRLCGT
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery (By similarity).
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: IF1_NEIG1
Sequence: MAKEDTIQMQGEILETLPNATFKVKLENDHIVLGHISGKMRMHYIRISPGDKVTVELTPYDLTRARIVFRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM41_YEAST
Sequence: MLRVSENGLRFLLKCHSTNVSMFNRLLSTQIKEGRSSIDDAGIIPDGTINERPNHYIEGITKGSDLDLLEKGIRKTDEMTSNFTNYMYKFHRLPPNYGSNQLITIDKELQKELDGVMSSFKAPCRFVFGYGSGVFEQAGYSKSHSKPQIDIILGVTYPSHFHSINMRQNPQHYSSLKYFGSEFVSKFQQIGAGVYFNPFANINGHDVKYGVVSMETLLKDIATWNTFYLAGRLQKPVKILKNDLRVQYWNQLNLKAAATLAKHYTLEKNNNKFDEFQFYKEITALSYAGDIRYKLGGENPDKVNNIVTKNFERFQEYYKPIYKEVVLNDSFYLPKGFTLKNTQRLLLSRISKSSALQTIKGVFTAGITKSIKYAWAKKLKSMRRS
What is the function of this protein?
Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane.  Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.
What are the official names of this protein?
Phosphatidate cytidylyltransferase, mitochondrial, CDP-diacylglycerol synthase, CDP-DAG synthase, Mitochondrial import protein MMP37, Mitochondrial matrix protein of 37 kDa, Mitochondrial translocator assembly and maintenance protein 41.
What is the protein family that this protein belongs to?
Belongs to the TAM41 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: EFTS_PARXL
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEADGDMARAEELLRVKLGNKASKAASRVTAEGVVASFIGGNAGSLVELNCETDFVSKNDDFLAFSKKVAELVATQNPADVAALSALPLDGSTVDAVRLALVGKIGENLSIRRFVRFDTANKLAAYLHGTRIGVLVEYTGADEQVGKDVAMHIAAMKPVSLSSEDVPAELIAKERSIAEQKAAESGKPAEIVAKMVDGSVQKYLKEVSLLNQTFVKNDKQTIEQMLKAGNASVQKFALFVVGEGIEKKQDDFAAEVAAQVAAAKQQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_HYPNA
Sequence: MTNPQDSKAIWHGTTVLAVRKNGKLVMLSDGQVSMGQTIMKGNARKVRRIAGGQILAGFAGATADAFTLFERLEAKLERFPDQLQRAAVELAKDWRTEKYLQKLEALLIVADKHSTLVITGAGDVLEPEHHVVSIGSGGNYALAAARGLYDYEEDAETIGRKAMQIAADICVYTNGHFSVETLEI
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_MARMS
Sequence: MSLESYMNQIGQQARAASRLLAKASTKQKNMALFAMAEALENARPRLVEENAKDMENGRAKGLDSALLDRLLLDDKRIDGMIEGLKQVASLPDPIGEISDMVYLPSGIQRGQMRVPLGVIGIIYESRPNVTIDAASLCLKSGNATILRGGSEAFYSNQAIAEAVTAGVVAAGLPEHAVQVLNTTDREAVGKLISMPEFVDVIVPRGGKGLIERISKDARVPVIKHLDGNCHVYIDDEADLDKAFAIAMNAKTRRYGVCNAMESLLVHASVAGDILPKLVFALQEKGVSLVGCDQVRSVSGEIGAATEEDWYTEYLAPKLSIKIVANMDEAIAHINKYGSHHTDAIVSQNYTKARAFMTEVDSSSVMVNASTSFADGFEYGFGAEIGISTDKIHARGPVGLLGLTSQKYVVLGDGHTRDN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_PHEZH
Sequence: MKQDTHPDYHFITVVMTDGTTYKTRSTLGKEGDTLNLDIDPKTHPAWTGGGHQLLDRGGRVSRFNAKFGAFTRK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: STCV_EMENI
Sequence: MAAPPAPQPPSLLGYHRVLSPLAGIRVSPLCLGTMHFGGQWTRAMGDVTKETAFALLDRFYEAGGNFIDTANFYQGEGSEKWLGEWVASRGNRDELVLATKYTMSYRLTGPEKIKSNFQGSHSKSLRLSVEASLAKLRTDYIDLLYVHMWDFSTSVEEVMQSLHHLVAAGKVLNIGISDAPAWVVAKCNEYARFHGLTRFCVYQGRWACSYRDFEREILPMCQSEGLALAPWGALGRGQYKSAEEFQQEGTRNMGPQEEKHRLMGAKLTEVGERKGVAAAAIALAYLLHKSPYVFPVIGCRTVEQLEANITSLGVELSDEEIYEIEDTIPFDVGFPMAFLFESPQQKYRSDMTTRHIWQVTCNARIESVPKPRPIEPKQGYKQMDRK
What is the function of this protein?
Norsolorinic acid reductase; part of the gene cluster that mediates the biosynthesis of sterigmatocystin (ST), a polyketide-derived furanocoumarin which is part of the most toxic and carcinogenic compounds among the known mycotoxins (PubMed:8643646).  The first step in the biosynthesis of sterigmatocystin is the production of hexanoate by the fatty acid synthase (FAS) units stcJ and stcK (PubMed:8962148).  The polyketide backbone is assembled by the non-reducing polyketide synthase stcA by condensation of the starter hexanoyl-CoA and 7 malonyl-CoA extender units followed by cyclization and release of norsolorinic acid (By similarity).  Norsolorinic acid is the first stable intermediate in the biosynthesis of sterigmatocystin and is converted into averantin (AVN) by the ketoreductase stcE which reduces the hexanoate ketone to an alcohol (PubMed:8643646) (Probable).  Averantin is then oxidized into 5'-hydroxyaverantin (HAVN) by the cytochrome P450 monooxygenase stcF (PubMed:10618248).  5'-hydroxyaverantin is further converted to 5'-oxyaverantin (OAVN) by the 5'-hydroxyaverantin dehydrogenase stcG (PubMed:24957370).  The next step is the conversion of OAVN into averufin (AVF) which is catalyzed by a yet to be identified enzyme (PubMed:24957370).  The cytochrome P450 monoxygenase stcB and the flavin-binding monooxygenase stcW are both required for the conversion of averufin to 1-hydroxyversicolorone (PubMed:10618248).  The esterase stcI probably catalyzes the formation of versiconal hemiacetal acetate from 1-hydroxyversicolorone (PubMed:24957370).  The oxydoreductase stcN then probably catalyzes the biosynthetic step from versiconal to versicolorin B (VERB) (PubMed:24957370).  The next step is performed by the versicolorin B desaturase stcL to produce versicolorin A (VERA) (PubMed:8999832).  The ketoreductase stcU and the cytochrome P450 monooxygenase stcS are involved in the conversion of versicolorin A to demethylsterigmatocystin (PubMed:7486998).  The Baeyer-Villiger oxidas stcQ and the reductase stcR might be involved in the biosynthetic step from versicolorin A to demethylsterigmatocystin (PubMed:24957370).  The final step in the biosynthesis of sterigmatocystin is the methylation of demethylsterigmatocystin catalyzed by the methyltransferase stcP (PubMed:8900026).
What are the official names of this protein?
Norsolorinic acid reductase stcV, Sterigmatocystin biosynthesis cluster protein V.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: ACHAA_XENLA
Sequence: MDFVLTRLILLFLAATIIYSSEDESRLINDLFKSYNKVVRPVKAFKDKVVVTVGLQLIQLINVNEVNQIVTTNVRLKQQWEDVHLKWDPEDYGGIKKVRIPSSDIWRPDIVLYNNADGDFAIVQETKVLLDYTGKIIWLPPAIFKSYCEMIVTYFPFDLQNCSMKLGTWTYDGTLVVINPENDRPDLSNFMESGEWYMKDYRCWKHWVYYDCCPETPYLDITYHFLLQRLPLYFIVNVVIPCLLFSFLTGLVFYLPTDSGEKITLSVSVLLSLVVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIVITVIVINTHHRSPSTHIMPQWLKKIFIETIPRVMFFSTMKRPAQDQHKKKIFTEDIDISDISGKLGPTAVKYQSPILKNPDVKSAIEGAKYVAETMKSDQESTKASEEWKFVAMVLDHLLLAVFMIVCIIGTLAIFAGRLIELHMQG
What is the function of this protein?
Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit alpha-1-A.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: YIDD_PELUB
Sequence: MNIISNILIGLIKFYKMVISPYLTPSCRYLPTCSEYTIECLRTYGLVKAISKSTKRIFSCHPIKILGGGEGFDPVNKEFKAKK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RFC3_DICDI
Sequence: MLWIDKYKPTSLDKMDYHNDISINLKNMIKSGDFPHLLVYGPSGAGKKTRILAVLQEIYGPNALKLKIDHRTFKHPTSSKNIQITTISSHYHIEINPGEAGSYDRVVIQTIIKEIAQSPPIDSGSLGAFKIVILNEVDKLSKDAQHALRRTMEKYATFCRLILCCDSTAKVIDPIKSRCLGIRVPAPSQEEIEKVLAKVATAEKFDLPSKLAVNVAKQSGGNLRYALMLLESQKAKQYPFQSTELPLLDWENYISQIVKDCFEEQSPARLSIVRGKLYELLGHCIPPELIFKTLLLEIFKKLDHNMKFEIIHWASYYEHRSQIGSKPIFHLEAFIAKFMSVYKKYNQ
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.
What are the official names of this protein?
Probable replication factor C subunit 3, Activator 1 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRB_DEIGD
Sequence: MTVLAPPRPRSLLDFQDWLPERLSALLDNADTMHQVLERPVRKVPALQGLTVCTAFFENSTRTRISFELAARRMSADVISFAAGASSLSKGESLRDTVEVLSAYKVDAFVVRHPASGAAHLIARYSGKPVINAGDGRRAHPTQALLDAYTIRQEYGSLAGKKVAIIGDIRHSRVARSNAELLPKLGAEVVLAGPATLLPADLAALPGVTVTTDPKEAVHGAHAVMALRLQQERMNAGYLASLQEYVERYQVNEALLREAESGAIVLHPGPLNRDLEISSEVADGPQSRILKQVENGQAVRMSVLYHLLVGRD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CD79B_MOUSE
Sequence: MATLVLSSMPCHWLLFLLLLFSGEPVPAMTSSDLPLNFQGSPCSQIWQHPRFAAKKRSSMVKFHCYTNHSGALTWFRKRGSQQPQELVSEEGRIVQTQNGSVYTLTIQNIQYEDNGIYFCKQKCDSANHNVTDSCGTELLVLGFSTLDQLKRRNTLKDGIILIQTLLIILFIIVPIFLLLDKDDGKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE
What is the function of this protein?
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation.  Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
What are the official names of this protein?
B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Protein: YD286_MOUSE
Sequence: MLWFQGKSLQIAKSSFGLLRNLSASNRALPVLTLFTKAPCPLCDEAKEVLQPYKDRFILQEVDITLPENSTWYERYKFDIPVFHLNGQFLMMHRVNTSKLEKQLRKLEQQVLATN
What are the official names of this protein?
Glutaredoxin-like protein C5orf63 homolog.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. YDR286C subfamily.
Protein: TRMN6_PECCP
Sequence: MSHQADNKLTLRRDGFTFKQFFVAHDRCAMKVGTDGILLGAWAPLSSVTRILDIGSGSGLLALMLAQRSDTHVRIDAVELDSAASQQAKENISASPWADRIAVYAEDIIDFADTRSADYSLIISNPPYFPPGIACGSAEREQARYTTLLTHETLLRCAHQLLMPDGLFCVVLPIQVAENFIPLAQQHNWYVHQQLRVSEQEDKPAHRVLLALSRQKKECVNASLAIRDEERRYSTAFQQLTKDFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_ECO57
Sequence: MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_WOLPM
Sequence: MDMENNLQDLKKKFNDIERNLENPTNLSQKEFITLSKEYSELRPIIKIIDEYNTLKEEISDLEEIMKDENSEGDIKELAKEEFFEKHKVLLPKIKAKLKLALLPKDEDDSRNAILEIRAGTGGEEAALFAAMLFRMYQKYAERRNWKFEPISISNTGIGGYKEASALINGTEVFARLKFESGVHRVQRVPETESSGRLHTSAATVAILPEVEEVDFKIEEKDLRIDVYRSSGPGGQSVNTTDSAVRVTHLPTGIVVIQQDEKSQHKNKAKALKVLRARLYEIERQKKEMERSTMRKSQIGSGDRSERIRTYNFPQSRITDHRINLTSHRLEQIIKEGELDEFIEALISRNEAERLAGES
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_CLOBM
Sequence: MAIDVKAIEEHIRGILIALGDNPEREGLKDTPKRVAKMYEEVFKGMCYSNDEIAEMFNITFEDDLCINDNENDMVFMKEIEIFSHCEHHLALMYNMKVAIAYIPKGKIIGLSKMARIADMVGRRLQLQERIGSDIAEILQKITGSEDVAVIIEGEHGCMTTRGIKKSGTKTITTTLRGKFNTDPIISNKLMMLYTK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GLTD_HALED
Sequence: MANRLNNDFQFIDVGRQDPEKKPARTRAKQFAEIYEPYKPQDAAAQAHRCLHCGNPYCEWKCPVHNYIPNWLQLVSEGNILEAAELSHRTNSLPEVCGRVCPQDRLCEGDCTLNDGFGAVTIGSVEKYITDTAFAMGWRPDMSKVTWTDKKVAIIGAGPAGLGCADILVRNGVKPVVFDKYPEIGGLLTFGIPEFKLEKTVMERRRAVFEEMGVEFCLGVEIGRDMPFEQLLEEYDAVFLGMGTYKYMEGGFPGEDLPGVHKALDYLVANVNHCLGFETDPADYVSLEGQRVVVLGGGDTAMDCNRTAIRQGAASVTCAYRRDEDNMPGSRKEVANAREEGVDFLFNRQPVAVIGEDRVEGIKVVRTRLGEPDENGRQRPEVVPGSEEVVPADAVVIAFGFQPSPAPWFETVGIELDEKGRVKAPEEGAYAFQTTNEKIFAGGDMVRGSDLVVTAVFEGRQAGEGILDYLDV
What is the function of this protein?
Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate.
What are the official names of this protein?
Glutamate synthase [NADPH] small chain, GOGAT, Glutamate synthase subunit beta, GLTS beta chain.
Protein: CH10_STRMK
Sequence: MSIKPLHDRVVVKPIEADEISAGGIVIPDSAKEKSTKGEVVAVGPGKPLDNGNVRAPSLKVGDKVIYGQYAGSSYKSEGVEYKVLREDDVLAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_SHIF8
Sequence: MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAAMLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: PUR7_METS3
Sequence: MDKKELINNGKVKSVYTTDDENAVIIEFRDDMTAGDGARKEVMNKKGSYNALISTKLFKVLEENGIKTQFIDLPETNVMVAKKLEMIPIEVIVRNIATGSLIRKYPIADGTKLDPPIVQMDFKADEFHDPMLNDSIIKALGLATQEEIDELTEKALKINEVLSEFLLEAGIILVDFKVEFGKDKNGEIILGDEISPDGCRLWDSETLDMLDKELFRKGKDNEVMDAYVEVYNRIIPDDEKIEL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MCA4_ARATH
Sequence: MTKKAVLIGINYPGTKAELRGCVNDVRRMYKCLVERYGFSEENITVLIDTDESSTQPTGKNIRRALADLVESADSGDVLVVHYSGHGTRLPAETGEDDDTGFDECIVPCDMNLITDDDFRDLVDKVPPGCRMTIISDSCHSGGLIDEAKEQIGESTKKEAEDEDESEESSSRFGFRKFLRSKVEGAIESRGFHIGGNKKDEDEAEEIETKEIELEDGETIHAKDKSLPLQTLIDILKQQTGNDNIEVGKIRPSLFDAFGDDSSPKVKKFMKVILGKLQAGNGEEGGLMGMLGKLASGFLEGKLNDEDYVKPAMQTHVGSKEEVYAGGSRGSVPLPDSGILISGCQTDQTSADATPAGKPTEAYGAMSNSIQTILEETDGEISNREMVTRARKALKKQGFTQQPGLYCHDGYANAPFIC
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine or lysine residues.  Does not cleave caspase-specific substrates.  Plays a positive regulatory role in biotic and abiotic stress-induced programmed cell death.
What are the official names of this protein?
Metacaspase-4, AtMC4, Metacaspase 2d, AtMCP2d, Metacaspase-7.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RNH_PSEU2
Sequence: MSDSVELFTDGACKGNPGPGGWGALLVCKGVEKELWGGEANTTNNRMELTGAIRGLEELKRPCEVTLVTDSQYVMKGITEWMVNWKKRGWKTAAKEPVKNADLWQLLDEQVSRHTVKWQWVRGHIGHPGNERADQLANRGVDEVRGIRHG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_COLP3
Sequence: MTLSQQLSTLISKTQLVVSQEQIDLLIQYVELLNKWNKAYNLTSVRDPSEMLVKHIMDSLMVGEVLIGKNFIDVGTGPGLPGIPLAILYPERNFVLLDSLGKRITFLRQVVFQLKLSNVTPVKARVEEYQGEEPFDGVLSRAFSSLNDMVSWCKHLITTEQGRFFALKGQYPQDEISQLPENITLVDSHEIIVPDLVGERHVIVLKKLH
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.