PharMolix/UniProtQA huggingface dataset:
Protein: Y2276_PSYIN
Sequence: MFSKEGMGDLMKKAQEMQENMKKAQAEIANTEVTGESGAGLVKITILGNHNVRKVEIDPSLMEDDKEMLEDLIAAAMNDAVHRIGEVNKNKMSGVSGGMELPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Ping_2276.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CO4A1_CAEEL
Sequence: MSRLSLLGLTAAVVLLSSFCQDRIHVDAAAACKGCAPPCVCPGTKGERGNPGFGGEPGHPGAPGQDGPEGAPGAPGMFGAEGDFGDMGSKGARGDRGLPGSPGHPGLQGLDGLPGLKGEEGIPGCNGTDGFPGMPGLAGPPGQSGQNGNPGRPGLSGPPGEGGVNSQGRKGVKGESGRSGVPGLPGNSGYPGLKGAKGDPGPYGLPGFPGVSGLKGRMGVRTSGVKGEKGLPGPPGPPGQPGSYPWASKPIEMEVLQGPVGPAGVKGEKGRDGPVGPPGMLGLDGPPGYPGLKGQKGDLGDAGQRGKRGKDGVPGNYGEKGSQGEQGLGGTPGYPGTKGGAGEPGYPGRPGFEGDCGPEGPLGEGTGEAGPHGAQGFDGVQGGKGLPGHDGLPGPVGPRGPVGAPGAPGQPGIDGMPGYTEKGDRGEDGYPGFAGEPGLPGEPGDCGYPGEDGLPGYDIQGPPGLDGQSGRDGFPGIPGDIGDPGYSGEKGFPGTGVNKVGPPGMTGLPGEPGMPGRIGVDGYPGPPGNNGERGEDCGYCPDGVPGNAGDPGFPGMNGYPGPPGPNGDHGDCGMPGAPGKPGSAGSDGLSGSPGLPGIPGYPGMKGEAGEIVGPMENPAGIPGLKGDHGLPGLPGRPGSDGLPGYPGGPGQNGFPGLQGEPGLAGIDGKRGRQGSLGIPGLQGPPGDSFPGQPGTPGYKGERGADGLPGLPGAQGPRGIPAPLRIVNQVAGQPGVDGMPGLPGDRGADGLPGLPGPVGPDGYPGTPGERGMDGLPGFPGLHGEPGMRGQQGEVGFNGIDGDCGEPGLDGYPGAPGAPGAPGETGFGFPGQVGYPGPNGDAGAAGLPGPDGYPGRDGLPGTPGYPGEAGMNGQDGAPGQPGSRGESGLVGIDGKKGRDGTPGTRGQDGGPGYSGEAGAPGQNGMDGYPGAPGDQGYPGSPGQDGYPGPSGIPGEDGLVGFPGLRGEHGDNGLPGLEGECGEEGSRGLDGVPGYPGEHGTDGLPGLPGADGQPGFVGEAGEPGTPGYRGQPGEPGNLAYPGQPGDVGYPGPDGPPGLPGQDGLPGLNGERGDNGDSYPGNPGLSGQPGDAGYDGLDGVPGPPGYPGITGMPGLKGESGLPGLPGRQGNDGIPGQPGLEGECGEDGFPGSPGQPGYPGQQGREGEKGYPGIPGENGLPGLRGQDGQPGLKGENGLDGQPGYPGSAGQLGTPGDVGYPGAPGENGDNGNQGRDGQPGLRGESGQPGQPGLPGRDGQPGPVGPPGDDGYPGAPGQDIYGPPGQAGQDGYPGLDGLPGAPGLNGEPGSPGQYGMPGLPGGPGESGLPGYPGERGLPGLDGKRGHDGLPGAPGVPGVEGVPGLEGDCGEDGYPGAPGAPGSNGYPGERGLPGVPGQQGRSGDNGYPGAPGQPGIKGPRGDDGFPGRDGLDGLPGRPGREGLPGPMAMAVRNPPGQPGENGYPGEKGYPGLPGDNGLSGPPGKAGYPGAPGTDGYPGPPGLSGMPGHGGDQGFQGAAGRTGNPGLPGTPGYPGSPGGWAPSRGFTFAKHSQTTAVPQCPPGASQLWEGYSLLYVQGNGRASGQDLGQPGSCLSKFNTMPFMFCNMNSVCHVSSRNDYSFWLSTDEPMTPMMNPVTGTAIRPYISRCAVCEVPTQIIAVHSQDTSVPQCPQGWSGMWTGYSFVMHTAAGAEGTGQSLQSPGSCLEEFRAVPFIECHGRGTCNYYATNHGFWLSIVDQDKQFRKPMSQTLKAGGLKDRVSRCQVCLKNR
What is the function of this protein?
Collagen type IV is specific for basement membranes (Probable).  Required to restrict presynaptic growth at the neuromuscular junctions (NMJ) in late larval stage and in adult motor neurons (PubMed:25080592).  May play a role in axon regeneration in embryos following injury in D-type motor neurons (PubMed:27984580).
What are the official names of this protein?
Collagen alpha-1(IV) chain.
What is the protein family that this protein belongs to?
Belongs to the type IV collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: DRD2B_XENLA
Sequence: EWRFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISVVWVLSFAISCPLLFGLNNTASTVCIIDNPAFVIYSSIVSFYVPFIVTLLVYVQIYIVLRKRRKRVNTKRNSHGVGVDAHKDKCTHPEDVKLCAVFVKSNGSFPAEKKKVEAGNHPEDMEMEMMSSTSPPEKTKHKSASPEHQLAVPATSNQCNNVNLPTPVNSPYKAENNGHSKDSTQPAKVFEIQSMPNGKTRTSIKTMSKRKISQHKEKKATQMLAIVLGVFIICWLPFFITHILNMHCNCNIPQALYSAFTWLGYVNSAVNPIIYTTFNVEFRKAFIKILHC
What is the function of this protein?
This is one of the five types (D1 to D5) of receptors for dopamine.  The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.  In Xenopus D2R is involved in the regulation of the melanotrope cells of the intermediate pituitary during background adaptation of the animal.
What are the official names of this protein?
D(2) dopamine receptor B, D2R-B, D2R 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: XPB2_ARATH
Sequence: MGNDERKRPTKKMKYGGKDDQKMKNIQNVEDYYDDADEDSRDGEGEEKRRDFTDLELKPDHGNRPLWACADGKIFLETFSPLYKQAYDFLIAIAEPVCRPESMHEYNLTPHSLYAAVSVGLETETIISVLNKLSKTKLPGEIIDFIHASTANYGKVKLVLKKNRYFIESPFPEVLKRLLSDDVINRARFTSEPYYGGDGFTIGKTSGELEAGPGELLNEAELAAAAEEKETHSFEIDPALVENVKQRCLPNALNYPMLEEYDFRNDNVNPDLDMELKPHAQPRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLVGVSAAARIKKSCLCLATNAVSVDQWAYQFKLWSTIKDDQICRFTSDSKERFRGNAGVVVTTYNMIAFGGKRSEEAEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGLTATLVREDEKITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKKENSKKKQALYVMNPNKFRACEFLIRFHEQQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKTVNTVFLSKVGDNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLVSTDTQEMYYSTKRQQFLIDQGYSFKVITSLPPPDAGSSLGYHSQEEQLSLLGKVLNAGDDMVGLEQLEEDTDGKALKTRRSMGSMSAMSGANGRVYMEYNSGRQKSGNQSKKPKDPTKRHNIFKKRYV
What is the function of this protein?
ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  The ATPase activity of XPB, but not its helicase activity, is required for DNA opening.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  The ATP-dependent helicase activity of XPB is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH helicase subunit XPB2, TFIIH subunit XPB, ERCC3 homolog 2, RAD25 homolog 2, AtXPB2, XPB homolog 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD25/XPB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGA_GEOTN
Sequence: MKVLFAVSECAPFAKSGGLADVAGALPKELRRLGIDARVMLPKYETIAPEWKKKMKKVAELIVPVGWRRQYCGVEELRHDGVIYYFIDNEYYFKRPQLYGHYDDGERFAYFCRAVLEVLPEIQFQPDVIHCHDWHTGMVPFLLREQYRHELFYVDMRTVFTIHNLQFQGLFPRGILEDLLNLDGRYFTVDHLEFYGCVSFMKGALVASDLITTVSPTYKEEIQTAYYGERLDGLLRARRDDLLGILNGIDDEFYNPEADPFLTATYSVHTRERKQLNKRALQRQFGLPEWDDVPLIAMVTRMTAQKGLDLVTCVFHEMMSEDMQLVVLGTGDWRFEQFFSQMAAAYPGKVGVYIGFHEPLAHQIYAGADLFLMPSLFEPCGLSQMIALRYGTIPIVRETGGLNDTVQSYNEITKEGNGFSFTNFNAHDMLYTIRRALSFYRQPSVWEQLTERAMRGDYSWRRSANQYKQAYEQLIKKEEHTLVHG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RL37_THEON
Sequence: MGSGTAPKGRRNHTPTHIKCRRCGKRSYNIKKGYCASCGFGRSRRMRKYSWSHKWKKKRNLL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: DNAS1_HORSE
Sequence: MRGARLTGALLALAGLLQVALSLRIAAFNIRTFGETKMSNDTLSNYIVQILNRYDIALIQEVRDSHLTAVGKLLDRLNQDDPNTYHFVVSEPLGRNNYKERYLFVFRPDQVSLLDSYQYNDGCEPCGNDTFSREPAIVKFSSPFTQVKEFAIVPLHAAPSDALAEIDSLYDVYLDVQQKWDMEDIMLMGDFNAGCSYVTSSQWPSIRLRRNPAFWWLIPDTADTTVKSTHCAYDRIVVAGTLLQEAVVPDSAVPFDFQAAYGLNDQTAEAISDHYPVEVTLM
What is the function of this protein?
Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (By similarity).  Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA.  Among other functions, seems to be involved in cell death by apoptosis.  Binds specifically to G-actin and blocks actin polymerization (By similarity).  Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs).  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation.  Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation (By similarity).
What are the official names of this protein?
Deoxyribonuclease-1, Deoxyribonuclease I, DNase I.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Secreted. Zymogen granule. Nucleus envelope. Note=Secretory protein, stored in zymogen granules and found in the nuclear envelope.
Protein: HIS2_RHOOB
Sequence: MKEWVLVKTFESLFAELTERAATRPEGSGTVAALDAGVHSQGKKILEEAGEVWIAAEHESDEALAEEISQLLYWTQVLMVGKGLKLEDVYRHL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRL_CAEEL
Sequence: MNPDEVNRALGHYLNDADSGELVVEDSTTVQVKNPEARKTGDKIEVFYSRKTTVVSPTNSDDEDADFCSDSELLPQQEGHRSRATSFAGRIRAGSDDEAMPKHTILRYRRKKGGQWREINLQGTPDKRKDDEDELEVDVKEDRSEQTGIVTKTYEARWKVLKYEHLPEWLQDNEFLRHGHRPPLPSFSECFKSIWSLHTETGNIWTHLIGCVAFFFLACWFLTRPDNHIQFQEKVVFSFFFAGAVLCLGLSFAFHTLSCHSVNVVKIFCKLDYMGISLLIIGSFIPWIYYGFYCRREPKITYIAMVSVLGIGAIVVSLWDKFSESRFRPIRAAVFVGMGCSGVIPTIHYIITDGVHSLFADNSFHWLLLMAFLYLLGAGLYATRTPERFFPGKCDIWFQSHQLFHTCVVIAAFVHYYGISEMAFARLNEQCPVR
What is the function of this protein?
Probable receptor, which may be involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation.
What are the official names of this protein?
Progestin and adipoQ receptor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL32_RICPU
Sequence: MAVPKKKTSKSRRNMRRSHLALGKVNVIVDSQTGEYKLPHHVSLVDGTYNNRLVVTKKIKTEEEVA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: DUT_RICRS
Sequence: MTITQVKIKKLENFSGSLPEYATEHSAGMDLIAANEQPITIKAAAIQLIPTGIAIALPDSFEAQIRPRSGLAVKHGITVANSPGTIDADYRGEIKVILINLGKEDFIIEKGMRIAQMIIAKYERILWEESISLMETMRGSGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PYRG_TREDE
Sequence: MKSKFIFITGGVVSSLGKGLTAASIGMLLKSRGYSVVNQKFDPYLNVDPGTMNPYQHGEVFVTEDGGETDLDLGHYERFTDVPLHKFNSTSAGKVYLAILDRERAGGYNGGTVQVVPHVTDEIQSRILGTAEQTGADFVISEIGGTVGDIEALPFIEAIRQIRYTVGKENCMFVHLGLLPYLKECGEIKTKPMQHSVKELLSFGIQPDILICRSEKRLSKSTREKLSLFSNIPQDAIIENLTAKSIYEVPLMLEEAGLGKVLCKLFNIENKEPNLEEWKKMVQTYYNPEKEITIALVGKYVELPDAYLSVAEALTAAGIYHKTSIKLLWIDSKKIETKEDAAAFLKDADGIIVPGGFGDRGINGMLLTAQFARENKIPYFGICLGMQISAIEYALNALHIEEANSSEFDKNAKNPVIDLMPDQKDVKIGGTLRLGLYRCMIAEGSLAEKAYKSHEIQERHRHRYEFNNLYREKFDNSDMIFSGLNPERNLVEIVELKSHPWFVAVQFHPEFASRPNKPHPLFRDFIKAAVDNKINR
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TATA_LEPIC
Sequence: MFAPLAVFGSLGWTEILLILFIALLLFGGKRLPSLAKDLGDGIRSFRKSLTGESDDSSQQISQEQERSVPKEETKTSKSKKSKSA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LRC3B_MOUSE
Sequence: MNLVDLWLSRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV
What are the official names of this protein?
Leucine-rich repeat-containing protein 3B, Leucine-rich repeat protein 15.
What is the protein family that this protein belongs to?
Belongs to the LRRC3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYFB_RHOPA
Sequence: MKLTLSWLKDHLDTDEPLEKLADKLTMIGLEVEGIEDKAKVLAPFTIAKVLTAAKHPNADKLQVCTVDVGDGAAPVQVVCGAPNARAGLVTVFAPPGTYIPAKDFTLGIGNIRGVESRGMLCSAAELQISEDHDGIIELPADAPVGAAYAAWAGLGDPVLDINLTPNRQDCAGVHGIARDLAAADMGKFKDPGIKPIKGEFPCPVSVTVEDSTLCPGFALRLVKGVKNGPSPEWLQKRLTAIGLRPINALVDITNYLTFDRSRPLHVFDAAKVKGNLVVRRAKDGETLLALDGRTYTLDSSVCVIADDHGVESLAGIMGGELSGCSAETTDVLIESALWNEINIAQSGRKLGINTDARYRFERGVDPAFMLPGLELATKLVMEFCGGTPSDVVVVGNPFADDKIIDFPLAEVKRLAGIEVSLTEIRRILNHLGFTVVGQAPVVKVAVPSWRSDVHGKADIVEEIVRIVGVDKVPLTPFERGDAPRKPVLTQIQNRTRRAKRALAARGLTEAVTWSFISKPFAEAFGGGQPELALANPIASDLSDMRPSLLPGLIAAAQANADRGSPDLALFEVGQVFKGDRPQDQFMAASGVRRGVASSAGLGRHWSGSAQATALDAKADAFAVLAAAGAPMAGLQIATNKLPAWLHPGRSGAIQIGPQNVLGYFGELHPRVLEQLGADGPLVAFEVILEKIPDPKQRPTRAKPALELSAFHPVSRDFAFIVDRKVAVADIVRAAQGVDKKLITSVSVFDVYEGKGIDPDKKSVAIAVTLQPRDKTMTDQEIEAVAAKIVAEVTKKTGGSLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_KINRD
Sequence: MARLFGTDGVRGLANVDLTADMALGLAVAAASVLVEPGGNAHPRALVARDPRASGEFLSAAVVAGLASAGVDVLDIGVVPTPALAHLVDTSGADFGVMLSASHNPMPDNGLKIFARGGTKLPDDVEDVVERAYREGGGRRPTGAAVGRVHGGPDVEQDAQDTYVAHLLSTLPGGPGSLKGLHVVVDCANGAASAVSPRVLAEAGARVTTIFAAPDGLNINDGCGSTHLGPVTAAVLAHGADIGLAHDGDADRCLAVDARGNAVDGDQIMAVLTLALRDRGQLTDDTLVATVMSNLGLRLAMQREGVTMVETGVGDRYVLEALNAGGWSIGGEQSGHVVLPAHATTGDGVLTGLHLLARMAETGRSLEDLTGVVQRLPQVLVNVRGVDKSRAGSDAELLGAVADAERELGETGRVLLRPSGTEPLVRVMVEAAHTDHAQGVADRLADVVRKRLAL
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DNJC2_RAT
Sequence: MLLLPSAAEGQGTAITHALTSASAVCQVEPVGRWFEAFVKRRNRNASTSFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKTMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKENFFQVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERKWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEGKAKKEAEKRAKAEARRKEQEAKEKQRQAELEAVRLAKEKEEEEVRQQALLAKKEKEIQKKAIKKERQKLRNSCKNWNHFSDNEADRVKMMEEVEKLCDRLELASLQCLNEILASSTREVGKAALEKQIEEVNELMRKEKEEADARMRQASKNAEKSTGGSGSGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVAPQADSAAPSERFEGPCIDSIPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRRYKELVEMVKAKKAAQEQVLNASRARK
What is the function of this protein?
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus.  When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state.  In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain.  When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
What are the official names of this protein?
DnaJ homolog subfamily C member 2, Gliosarcoma-related antigen MIDA1, Zuotin-related factor 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: MET3_CRYNJ
Sequence: MANAPHGGVLKDLLVRDAALHDSLLQEARSLNDIFLTERQLCDLELILNGGFSPLEGFMNERDYTSVVETLRLAPYNGQKHGDVFPIPITLDVSQEDINTLGLKQGGRVALRDPRDDAALAILTVSDIYRPNKAIEAEKVMGADDIAHPSVAYLRNNVKEFYVGGKVQAIQAPTHFDYVPLRFTPAELRAHFHKLAWRKVVAFQTRNPMHRAHRELTVRAARQRRANVLIHPVVGLTKPGDVDHYTRVRAYQALMPSYPEGMAHLALLPLAMRMAGPREAVWHAVIRKNFGATHFIVGRDHAGPGKNSQGQDFYGPYDAQELVTQFKDELQIEMVPFQAMTYLPGSDEYQPVDEVPKGTPTADISGTELRKRLRTGASIPDWFSYTGVVKVLRESYPPRPQQGFTILLTGLHNSGKDTIARALQVTLQQQGSRSVSLLLGEELRSDLDPQIGRAITPEQKHINLERIGFVAGELTKAGAAVIAAPTAPYERSRQAFKKQVVGSGGGNYFLVHVATPLEWCEKVDRRGLYKAARAGEIKNLTGVDDVYEAPEDADLVCDLRNDTVPEIVHSIIMILESQNLV
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX14_ARATH
Sequence: MTEEDSSAKMSEDVEKYLNLNPPCSSSSSSSSAATFTNKSRNFKSSPPPCPDHVLENVLENVLQFLTSRCDRNAVSLVCRSWYRVEAQTRLEVFIGNCYSLSPARLIHRFKRVRSLVLKGKPRFADFNLMPPNWGAQFSPWVAATAKAYPWLEKVHLKRMFVTDDDLALLAESFPGFKELTLVCCEGFGTSGIAIVANKCRQLKVLDLMESEVTDDELDWISCFPEGETHLESLSFDCVESPINFKALEELVVRSPFLKKLRTNRFVSLEELHRLMVRAPQLTSLGTGSFSPDNVPQGEQQPDYAAAFRACKSIVCLSGFREFRPEYLLAISSVCANLTSLNFSYANISPHMLKPIISNCHNIRVFWALDSIRDEGLQAVAATCKELRELRIFPFDPREDSEGPVSGVGLQAISEGCRKLESILYFCQNMTNGAVTAMSENCPQLTVFRLCIMGRHRPDHVTGKPMDDGFGAIVKNCKKLTRLAVSGLLTDEAFSYIGEYGKLIRTLSVAFAGNSDKALRYVLEGCPKLQKLEIRDSPFGDVGLRSGMHRYSNMRFVWLSSCLISRGGCRGVSHALPNVVVEVFGADGDDDEDTVTGDYVETLYLYRSLDGPRKDAPKFVTIL
What are the official names of this protein?
F-box protein FBX14, Transport inhibitor response 1-like protein, TIR1-like protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRYB_DROER
Sequence: MLKFVILLSAVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYTDRVIVTAAHCLQSVSASSLQIRAGSSYWSSGGVTVKVSSFKNHEGYNPNTMVNDIAVIRLSSSLGFSSTIKSISLASSNPANGAAASVSGWGTQSSGSSSIPSQLQYVNVNIVSQSKCASSAYGYGSEIRNTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYASVADLRSWVINNA
What are the official names of this protein?
Trypsin beta.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: CDD_SHIBS
Sequence: MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHSIDRVLLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: RM04_ASHGO
Sequence: MENYYTLSGNQEGVASCYRIAEDSEGVISMWVFQRGLHSSRSVLARTRYTKPKPKPPRRSKVRAPTQTTHHDTDLKVTAPIPPAAANLECNPEHPLWQFFDGGRFMRSAEELDDKSRPWTVPELRRKSFDDLHSLWYACLKERNILAREMHLRRNMQEEGSAHAQLDERVRTTMWRIRHVLSERDWAYRLAHAELGTQQAPLLREVEEAFLAVPEAEDGEAFDMLARLQRAVFGISEYIEENLVDRRFVDGLKYIATLKLRRFAPRDAAVEQLLQASEGGITDAGEAFVIFTAENTLADVKEAADAVNELREQGNKVDRYEEIATVAQYLKKLANAKKVAA
What are the official names of this protein?
54S ribosomal protein L4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARI5B_DANRE
Sequence: MVSDLRSWKKGLQAVPLKPGVLKELGKNGQREALHKYRESTLNSGLNFKDVLKEKAELGEDADDKKVLVLSYPQYCRYRSIIARLRERPSSLLTDHVVLALGGIASLTNSTQILYCRDTFEHPTLVENESVCDEFAPNLKGRPRKKKLSISQRRDSQSGGARESNGVEGKTLVKMRADSKSGVSKPRNPSTGSCKRVQSENKPKGDGGDECRTDEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYEVITARRQWKNVYDELGGNPGSTSAATCTRRHYERLILPYERFTKGEEDKPLPPAKPRKQEGSVQESIIKAKMMPIKRPKDEQKTPRGDKDASAKVLELGMEDMEELQEKQNSQQLQAPTQTDRDPNSPLTEDDEGVLVIKDEDQPVLHNAYEHANGGLLPSLPQDGAQLKSEDCDAFPVAAVPLHHGHPLPNSHTSDQWKHGILEYKVPPSALANVEQSRPKEGQNQVVMVLPTLQQKPVTSPEIPPERVEPLKKEESCFNFNPLLYPRGNPGIMSPLAKKKMLSQVSGTGLLNNYPYGPPPPLVSRRLSSSGTEVSSAGQSSSQVSSSVETSIVIKRPSVIQHAQSFKSRGSEDRRSSTEGSQKDGCSEGEPVHHSQTLIREPYLKRVDPHSSMEKSAEMPRPGQAPSFLSEFYSSPHLHNLCRQTEHHLSKEQISKYLSRDVYTRDSETAQGFPPSQHPDNVGLNFSARLSQKEKGPPPERVTEEQPTDLSLPKSSPLKLPLSTSTLGGIPHAAIQQDIKNSPHFQAGNSQSSSVDYHPRACRVPPMTVSASKKVTESHSKVLEKTPNSRGEESMGFKIDEMSRPILSTKSSPQNICTARPLKRNIEDLENGPTEKKIRAVTPLHCSTQRDLPGKPRTPEADSESVKPAEPAVHINSYTSEGHKIPLHSHLFQGLYPGTFVSQVQDMCESLGSHVTPSYSHPLQYLKNQAVLSPLMPPFAIHSLMMQRQFLAANPAHMYRHQVGTSYGDILHPGLYPMSALHPQPAFSPPQLSSVHPSTKLS
What is the function of this protein?
Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development.  Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity).
What are the official names of this protein?
AT-rich interactive domain-containing protein 5B, ARID domain-containing protein 5B.
What is the protein family that this protein belongs to?
Belongs to the ARID5B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UVRC_DEHM1
Sequence: MPSETLQNQIASLPENPGVYLMKNAQGEIIYVGKAAVLKDRVKSYFVPPSRLEPKTRQLVSQINELEYLITGSEQEALILELNLIKRHRPYFNVRLKDDKGFPYLKITLNEKWPRIYITRSMADDGGRYFGPFASTRSVRHTLQVLKELFRFRSCNRTEPEKRSRPCLEYDIHQCLSPCTGKISKQDYDHLISQAILFLEGKQDKVLKLLAKLMNEASARLDYETAALRRDQISSIKEVIEGQQLAARVSGEQDAIAFAQEGDLSMVQVFFIRRGKLIGRESFSLQGTREEKPGDILSEFVKQFYHSSTQIPPKIVTQYPLSDREILEKWLSERRGGKVQITAGLRGQPKDLINIVAENAREQLKQARIKNLSSAATLTDALEELQTALGLPLPPQRIEGYDISNIQGTNAVGSMVVFENGKPQKAHYRRFRIKTVKGADDFSMLKEVISRRFGRLNKDNAGESFARRPSLMLIDGGKGQLSSVKETLDTLGLEGQAVIGLAKEFEEIYLPGKSEPIRLMANSPALQLLQRVRDEAHRFALGYHLNIRHKSGLTSALDGIPGIGPSRRRLLIKTFGSVSGIRQASLDELLQVKGINQALALSIKELL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.