PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_LATVB
Sequence: MSGASEVPSFRWTQSLRRGLSHFTTSAKGDVLRDAKSLVDGLDFNQVSQVQRVMRKDKRSDDDLSKLRDLNRSVDSLMVMKNKQNNVSLKIGSLSKDELMDLATDLEKLKRKINLGDRQGPGVYQGNLTSAQLEKRSEILKSLGFQPRANQNGVVKVWDIKNPKLLINQFGSIPALTIACMSVQGAEQMNDVVQGLTSLGLLYTVKYPNLDDLDKLSKDHPCLEFITKEESANNISGYNLSLSAAVKAGACLVDGGNMLETILVKPDNFQDIVKSLLVVKRQEKMFVNEKPGLRNPYENILYKLCLSGEGWPYIGSRSQIVGRAWENTTVDLSKEVVYGPSAPVKNGGNMRLSPLSDTQEAVIKEAIGKLDMDETIWIDIEGPPNDPVELAIYQPSTGNYIHCFRVPHDEKGFKNGSKYSHGILLRDIENARSGLLSRILMRLPQKVVFTCQGSDDIQKLLQMNGRPDIATIDMSFSSEQARFFEGVVWEKFGHLCTRHNGVVLSRKKKGGNSGEPHCALLDCIIFQAAFEGQVTGQIPKPLLPNSLIFKDEPRVAM
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: ATP6_PSEPW
Sequence: MAAETASGYIQHHLQNLTYGQLPDGSWGFAHSAAEAKAMGFWAFHLDTLGWSVALGLIFLFIFRMAAKKATSGQPGGLQNFVEVMVDFVNGSVKDSFHGRSPVIAPLALTIFVWVFLMNAVDLVPVDWIPQLAILISGDPHIPFRAVSTTDPNATLAMAFCVFALIIFYSIKVKGLGGFIGELTLHPFGSKNIFVQILLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMFGSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEDNH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNLI_PYRAE
Sequence: MQFGELVKALAAIEATTQRTTMVKLLVSLFKKASPEEVGKIVYFILGDLRPPWEGVELGVAEKLCLRAVSKATGAAVSELEALYKKTGDVGEAARRALAASKRPGLLAFGSQKPLEVSEVYDTLLKVARATGEGAQDMKVALLSSLFARATPEEGKYIARFVVGKLRLGVADMTIIEALSDAYGVNKEALEKAYHIYPDLGRLAKHVAEGKPLDEIRITPGVPVLPMLAQRLSSASEILAKLGGSAICEYKYDGERAQIHLTPGGVKIFSRRLEDITHAYPDVVKAVKEAVSAKEAILEGEIVAVDPDTGDMLPFQELMHRKRKHDVATAVELYPTVLYLFDVLYVDGEDLTEEPLIYRRVRLSEIVCETDKVSIAKWRIFDNAEAVDVFFHESVSMGTEGLICKSPSSIYEMGARGWNWIKYKRDYRSEMIDTVDLVVVGAFHGRGKRAGLYGAFLLAAYDPSTDMFYTVCKVGSGFTDADLKKMYEILQPFKIPHRHPRVVSKMEADVWFVPQVVIEVIGAEITLSPLHTCCLGAVRPGVGLAVRFPRFTGRYRSDKSPEQATTVAEMLELYKRQKKVVQPE
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: PDXB_SALAR
Sequence: MKILVDENMPYARELFSRLGEVKTVPGRPIPVEELNHADALMVRSVTKVNESLLSGTPIKFVGTATAGTDHVDEAWLKQEGIGFSAAPGCNAIAVVEYVFSALLMLAERDGFSLRDRTVGIVGVGNVGSRLQTRLEALGIRTLLCDPPRAARGDEGDFRTMDEVVEEADVLTFHTPLYKDGPYKTLHLVDETLIRRLKPGAILINACRGPVVDNAALLARLTAGQPISVVLDVWEGEPDLNVALLDAVDIGTSHIAGYTLEGKARGTTQVFEAYSAFIGREQHVALETLLPAPEFGRITLHGPLDQPTLKRLAHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVMCDDASAAALLQKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUK_LISW6
Sequence: MSFDVLTINPGSTSTKLAVYQGDKVLFEETVRHTMQEFADFNNVQEQFDFRWQVLRRVIDAFGYDVNNLDAVVGRGGLLRPVAGGTYMVTEKMLADLKTNKYGEHASNLGAMLAKKLADTLDIPSFIVDPVVVDEMLPIARFSGNELIARKSIFHALNHKAAGRKIAKKLGSDYEKLNFVIAHLGGGISVAAHRQGKAVDVNNALDGDGPFSPERSGSLPMNDFLEACFSGKWNKRELHDLIIGRGGMISYLGTNSMLEVEAKVKAGDEKAIQAFDAMAYQVSKEIGACSTVLHGKIDAIILTGGLARSDLFTSKIIEQTNWIASVIIEPGEDELEALNSGVQRVLAGLEKEKLY
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSB_DROME
Sequence: MAVSALNMTPYFGGYPFQGQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCVSKILNRFQETGSIRPGVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSISRLLRGSSGSGTSHSIDGILGGGAGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQLNTQQVPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQSWPSSGAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQAQQPGTGSEFMTSTYGVGSSNATYPSAAYSMPQTPATSAEQLRSQFASAAASGSHHPSTWDSYNFAGSFFPPASAAGNHISGYHHQVDQKSSMMTTAPTYPYFGF
What is the function of this protein?
Expressed in segmentally repeating pattern to define the polarity of embryonic segments.
What are the official names of this protein?
Protein gooseberry, BSH9, Protein gooseberry distal.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYV_ARCFU
Sequence: MEIRKDYDAHEVEEKWLKLWKDEMYYFDWNSEKPHYIIDTPPPYPTGSFHIGHALNWCIIDFIARYKRMNGYEVMFPQGWDCHGLPTEVKVEEKYGIKKGDIPRDEFRRLCVEFTEENIAKMRETARRMGYSIDWSKEYITMYPEYYSKTQLSFVRMYNKGLIYRDYHPVVFCPRCETTIALAEIEYRQGKTKLNYIKFDDDVIIATTRPELIPACVAIAVHPDDERNKHLIGKKVRVPTTPYEVEVIADEEVDPEFGTGVVMICTFGDRQDVKWWKKHKLELRNIVGRDGRLNEKAGRYAGMTIPEAREAILEDLKKEGKLLKQVEIDHNVGTCWRCKTPVEIIPAEQWFVKVEKEKILEAAKRIKWVPEHMYSRLESWVQSMEWDWVISRQRIFATPIPAWYCKNCGEVVVAKEEWLPVDPTATQPPEPCPKCGSTEFRGETDVLDTWMDSSITPLMICGWPSLKEYPTHLRPQGHDIIRTWAFYTILRSLALEGQIPWYEIVINGMVFGEDGRKMSKSLGNVIVPEEVVEKYGVDALRQWAASGVIGDDIIFNWKDVIAASRFQQKFWSITRFTLMHISDYTPSEEDKKLLRDADRWILSKLNRLVGEVRKHMDEYRFDEAIKAIRTFTWYEYADNYLEIVKNRLYSGSEEEKRAAKFVLSYALDVLTRLLAPITPFMAEECWSHFREGSVHLQSYPVVEEEFLDERAEKAGEEIKEIVAAVRKFKHDKGLALNAPLKKLIVYSKLDGLDVRDIAGATNSEVEIVTEMPEVRERVKELKPKFAIIGPMFREKAKTLIKAVGSLSKEEKERLLKEGAIQVNLDGASVEVKAEWFEAVTEKSIEGREVEMLETANSVVFVEV
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_MYCSK
Sequence: MASYAIVKTGGKQYKVAVGDVVKVEKLDSEPGASVSLPVALVVDGANVTSKAEDLAKVAVTGEVLEHTKGPKIRIHKFKNKTGYHKRQGHRQQLTVLKVTGIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL4_HAEIG
Sequence: MELQVVGANALTVSETTFGREFNEALIHQVVVAYAAGARQGTRAQKTRAEVSGSGKKPWRQKGTGRARAGDIKSPIWRSGGTTFAAKPQDHSQKVNKKMYRGAIKSILSELVRQDRLVVVEKFELDAPKTKVLVQKLKDLAVEDALIITASLDENLFLAARNLYKVDVRDVQGIDPVSLIAFDKVIVTVDAVKQIEEILA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PSBM_NASOF
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NFYB8_ORYSJ
Sequence: MPDSDNDSGGPSNYAGGELSSPREQDRFLPIANVSRIMKKALPANAKISKDAKETVQECVSEFISFITGEASDKCQREKRKTINGDDLLWAMTTLGFEDYVDPLKHYLHKFREIEGERAAASTTGAGTSAASTTPPQQQHTANAAGGYAGYAAPGAGPGGMMMMMGQPMYGSPPPPPQQQQQQHHHMAMGGRGGFGHHPGGGGGGSSSSSGHGRQNRGA
What is the function of this protein?
Component of the NF-Y/HAP transcription factor complex.
What are the official names of this protein?
Nuclear transcription factor Y subunit B-8, OsNF-YB8, Transcriptional activator HAP3I, OsHAP3I.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_ECOL5
Sequence: MPLPDFRFIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTSDDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: HIR2P_HIRME
Sequence: ITYTDCTESGQDLCLCEGSDVCGKGNKCILGSNGEENQCVTGEGTPKPQSHNDGDFEEIPEEYLQ
What is the function of this protein?
Hirudin is a potent thrombin-specific protease inhibitor.  It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.
What are the official names of this protein?
Hirudin-2', Hirudin II'.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I14 (hirudin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PAN_METPE
Sequence: MADTLNHLPEPQKGEDLYRYLLERVTNLEDRNTELREQLRQIEADKRYLETQKVRYEREVRKFKGEIEQMKSPPLVIGTVTDLIDENRVIVRSSAGPRFLVGISQSLNIEEIKPGARCTLNQQSLAIVEILPTNYDAQIYGMEVIEAPSERYEEIGGLEKQINEIREAVELPLKKPEVFRKMGIEPPKGVLLHGPPGTGKTLLARAVAHQTEAHFLRVVGSELVQKYIGEGARLVRELFELAKKKSPSIIFIDEIDAIGASRTESNTSGDREVHRTLMQLLAEMDGFSNRGDVRIIGATNRIDILDRALLRPGRFDRIIEIPAPDIEGRVSILNIHCAGMNIDKKVDIRDIATRTDGKNGADLRSICMEAGMFAIRSDHEMVTLEDFEQSIEKFSNDFERDSLINTSGAMFA
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_BRASB
Sequence: MAEMKIADIRAMSPDQMDDAIVNLKKERFNLRFQRATGQLENTARLREARRDIARIKTIAAQQRAKTK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: UPP_BACCN
Sequence: MGKLYVFDHPLIQHKITYIRDKNTGTKEFRELVDEVASLMAFEITRDLPLEEIEIETPVSKAKTKVIAGKKLGLIPILRAGLGMVDGILKLIPAAKVGHIGLYRDPKTLQPVEYYVKLPTDVEERDFIVLDPMLATGGSAAEAINSLKKRGAKHIKLMCIVAAPEGVKVVQEEHPDVDIYVAALDEKLNDHGYVVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SYH_DESHY
Sequence: MAIQRPKGTQDLLPGVVEQWQDLEEQIRKICREYGYQEIRTPIFEATELFQRGVGETTDIVNKEMYTFLDKGDRSITLRPEGTASVCRAYVENKLHGGPQPVKLYYIGPMFRYERPQSGRFRQFHQFGVEVLGVDKPMVDAEVITLVWDLYSRLGLKGLEVHVNSVGCPSCRPEHKKKLQEFLAPRQEQLCKDCQSRFEKNPLRILDCKNPTCQEITQGAPTTLDTLCEECAEHFKELQSLLSAAEVVYKVNPRLVRGLDYYRKTAFEVLVEDIGAQSAICGGGRYDGLVQEVGGPPTPGIGFAMGMERVLAARKLAQGEQEGEGKEYLMLVALGDQAQREGFAIVSRLRKQGMPAGIDLLGRSLKAQLKAADRVQAHYAAILGEEELHKGIIILRDLRLGEQVELPLQDFEEVVWKRYKEDGN
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYCH_PSEAE
Sequence: MIDFWLAAGLLLLAALAFLLIPLLRGRRAQAEEDRTALNVALYQERIAELAGQQAAGTLTAEQLENGRAEAARELLADTEGSGEERSSRLGRAVPLVAALLVPLVALGLYLHWGASDKVELAREFAQAPHSMEEMTARLERAVQAQPDSAQGWYFLGRTYMTQERGADAARAFERAAELSGRQPEVLGQWAQALYFSGGKKMTAQIKALADEALKGDPAEVTTLGLLGIAAFEEQRYADAIGFWERLVSVLPNEDPARSAIQGGIQRARERMTEAGQTPPAPAAPAAAGVTLTVKVDISDAVKGQVKADDSVFVFARAVGGPPMPLAVKRLTVADLPAEVSLSDADAMMPQLKLSGFPQVELVARVSRAGNAISGEWIGRGKPLSTAQSSAQALTIDGPDQPQAARP
What is the function of this protein?
Required for the biogenesis of c-type cytochromes.  Possible subunit of a heme lyase (By similarity).
What are the official names of this protein?
Cytochrome c-type biogenesis protein CycH.
What is the protein family that this protein belongs to?
Belongs to the CycH family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Periplasmic side.
Protein: PETD_PROMP
Sequence: MSTLKKPDLSDPKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACVVGLAVLDPAMLGDKANPFATPLEILPEWYLYPVFQILRVVPNKLLGIALQTLIPLGLMILPFIENVNKFSNPFRRPVAMSVFLFGTFLTIYLGIGACLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RIC8_DROME
Sequence: METEHLKRLEAKEADHIPAILDEFNTKNADLLVFDSFRTDNLWHELWLAIFGILDDQRLSHLHTQCLNTVRILTRDEFSLQTNYIEQEVNTLLKLARIEAGSLKLPATPDELKQEEREEPQLEPSQAQSEVIAEALKCLCNLVYQSSDCRRQCLRQHCLDAILKRVASSMRHPCALEYYDMKLLFLLTALEPAARSRLQIDLNGLTYMTKWLDDKLGEDSVGEEQLNIICELLKVMFNVTSAPDKSPNEYEIQSLHLTGVLRELLLRFGDLATEKDRAVVTHAINLLTNISGSCLTELTLRCSNAELESHKEREQDNEKEKDTEAGAGAKPRECCSQCFEKRNVRSLDVLLRYLRQSLAQQEAEASSHELLSPVLTVLVKCARSDRVMRHYLRQEILPPLRDVSQRPEVGQELRNHLCRFLTLPAMILRDLSAELLFVLCKENVGRMIKYTGYGNAAGLFAKRGILDCRRVEGTDYSSDSEDSDTEEYKQQQQGINPVLGCVEPRSKSHLDDISEEQKEYEAMQLVNLIEQLRQGGIVKPAMIDKDGRPQPLEHILQLQEELPQQQLDQKRKT
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins independently of G-protein coupled receptors.  Acts by exchanging bound GDP for free GTP.  Plays a key role in asymmetric spindle positioning, a step for asymmetric cell division that generates cell diversity during development by activating G(i) alpha protein independently of G-protein coupled receptors.  In addition to its GEF activity, it plays an essential role in cortical subcellular localization of heterotrimeric G proteins, suggesting it acts as a facilitator of G-alpha function through control of its membrane targeting and/or assembling of associated components rather than a GEF.  Also required during gastrulation and sensory organ precursors (SOP) formation.
What are the official names of this protein?
Synembryn, Protein Ric-8.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes to the cell cortex.
Protein: KEX1_NEUCR
Sequence: MAATTTTTNAGRSMASWKRLSTLIAAFTLSWTSSFVAAAGSADYFVHDLPGAPDGPLVKMHAGHIEVTPDNNGNLFFWHFQNKHIANKQRTVIWLNGGPGCSSEDGALMEIGPYRLKDENTLVYNDGAWNEFANVLFVDNPVGTGFSYVDTNAYIHELTEMAANFVTFLERWFALFPEYEHDDLYIAGESYAGQHIPYIAQAILERNKNAGPVNRKWNLSGLLIGNGWVSPKEQYDAYLQFAYEKDIVKKGTDLANKLEIQQRICQKEIAVKPDKIDYPECEAILQDMLQLTAGGVGASGKNQCYNMYDVRLKDDYPSCGMAWPPDLKSVTPYLRKKEVIKALNINDNKSTGWTECNGQVGMNFNPKTKPSITLLPDILSAGVPILLFSGAEDLICNHLGTEALISNMEWNGGKGFELTPGTWAPRRDWTFEGEPAGFWQQARNLTYVLFYNSSHMVPFDYPRRTRDMLDRFMGVDISSIGGQPTDSRLDGEKLPETTVGGAAGNSTSNQAAEKAKLEMAKWEAYRKSGELVLVIVIVAAGVWGWFVWKERRKTAGQGYMGVATGERHSISNNPGPRGNLSGGGDRTRGQGLAGFRNKRSGRRDVEAQDFDESELDDLHLSKPEDPHADSRYSIGGASDDEEEQKPGKGSSSRQPGGRS
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase kex1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: RL11_RICAH
Sequence: MSQKAIKGYINLIIPAGGATPAPPIGPALGQRKVNIKTFCDEFNNSTKDMDKGVPLPTLITVYEDSSFSFKIKTPPASYFLKKYAKITKGSSATKKEAVVGKVTMDDCREIAKLKMPDLNTKDIEAATKIICGSAASMGLEVVGN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: UBIX_CHLMU
Sequence: MKRYIVGISGASGAILAVTLVSELARLGHHVDVIISPAAQKTLYYELETKSFLATIPSNLHKNILIHRITSIESSLSSGSTLVDATIIVPCSVATIAAISCGLSDNLLRRVADVALKEKRPLILVPRETPLSAIHLENLLKLAQNGAVILPPMPTWYFRPETANDIANDIVGKILAILQLDSPLIKRWENPH
What is the function of this protein?
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.  The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
What are the official names of this protein?
Flavin prenyltransferase UbiX.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family.
Protein: MIO_MOUSE
Sequence: MSGTKPDILWAPHQVDRFVVCDSELSLYHVESAVNSELKAGSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVRLSAGEAETTLLVTKPLYELGQNDASLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECAEEESDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNEDPQLKSLWYTLHFMKQYTEDNDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQTDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSEAGAYDGVLYENKVAVRDRVAFACKFLGDAQLNKYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSSVPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGSKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP
What is the function of this protein?
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway.  Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex.  It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
What are the official names of this protein?
GATOR complex protein MIOS.
What is the protein family that this protein belongs to?
Belongs to the WD repeat mio family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: OXGR1_HUMAN
Sequence: MNEPLDYLANASDFPDYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVRCKVSGNLEQAKKISYSNNP
What is the function of this protein?
Receptor for alpha-ketoglutarate.  Seems to act exclusively through a G(q)-mediated pathway (By similarity).
What are the official names of this protein?
2-oxoglutarate receptor 1, Alpha-ketoglutarate receptor 1, G-protein coupled receptor 80, G-protein coupled receptor 99, P2Y purinoceptor 15, P2Y15, P2Y-like GPCR, P2Y-like nucleotide receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACPS_CERSK
Sequence: MILGIGTDLANIDRMEKTLARFGERFRNRVFTPLEQAKAERRADVAGTYAKRWAAKEACSKALGTGLRMGISWKDMSVANLETGQPVMRLTGWAAERLASMTPPGHEAVVHVSLTDDHPWAQAFVVIEARPRAAPPA
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_ECOSM
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.