PharMolix/UniProtQA huggingface dataset:
Protein: IML1_KLULA
Sequence: MPPGELIFSNLRSGSRPVPRDRDALSSVQSDAISTKSSARYNFQGTGSSDATSGTNVTIRNNTLSIGVSSQMQGSAFNGPRMQLSTNGLKNTQSKALQAQSQDGCQDSKNIADNDSDAEARTAKRSLELELAFHEARFSNEQVMVDISSIKGAKEGDLAELKTYRTSPGSKDKKLYFIVKDFDTETRRRLKSFQISVLSGQLQQVLDLPIRSKVWVKLKEKKQLAVDLVELHVKDSYVNRGDMWKFSTQLHDSCVFLGQRVGLIETVRATVKGIYINGKKIFSGYIDENTKIVFRSESAKLLFMIQITDEMWHFEENGEETFHKVVNSLFPKIFRKWKNIGTHHSISIMFCASIDRSDSSFNDVTSGERLKNTDDYYRAVVDQVNIVHWVEIMKTLRKEFIRIAQDLRNVKLNENVSVIKGSLPSVIKSNLLETINLATTLVTDPFKQNDLRHTTTHAIIVTAGSGLYDVDYDLLKITTQKLMSLEITMDLICLSRPPLHIVPLLRYRDYKDQLHYCTPTWLSISFWNDSSRANVEWRPRCKIYNVLMMGLTETELKEEIALQSIKINDKCNSVSDFMESYDSAAFEVQSGPYSMHMDAALAAEFRSSKESKNDWNRRTVSKSKGNTNHIDTITWMKPKSTNAVLQPAFKEKVFAQLSSSPNSNLPRTEFEYKNQMTATNSLALNTLKRLSHANSGVTQKIISKLFPDLAIKKSQSSLRQKANIQPTDLTGSSSSLSDTGSQYKRSPNPKLLHKQKQLFDDNKKEASCGTSILSSQSSGNQRVQDKNFLLSETSLKTSKPNNKPKNGIKGDSWIEIENPSVPVDAELASYLIPNRWKDVFPKYVAKKYTKWRSFTTPAELPLTTSMFPTPFDFEHQFSLRNHTVSLNIEQEGYQQSVFDLLQNMIYVRLLAGFQFCLGKNVTRVEKARDKDTDGSRITHLINKENYRDVSIYLRIDNEIHRIVCFDETIDVQKYIKHDDSKLLQSFAKYTPYVKTRYEVEYRELDLDPVKTRRESYNWNQIDQVLAGFNDTIMDPATQKRFRCKFVILPAEIPPNTFQSTINGRKETLTAEEIRLEGLRKIISSISRSRLRTEHEKKDKRSHKEEILPEVLFYTGYLFDFIEEHNDFLKNSGAAVKNSIFMEDAETLSKDADLTKIAYELQHGVYQIKLVNRKWHWKRHENCFIGLELVNWLIEHFSDVHTREDAVVYGQELMNKGLFHHVESRHGFLDGHYFYQLNPEFTTENKTLYKTSTKHSNESHLMRKISTSNKSESAKSIDPTISVESNQQSEDQITKPEEHSITVLLSNAVTVDLDPSRKSYKLETCIAHYDRVHNPDHCFHIRLEWLTATPKLIDDLISNWSRLAERYGLKLVEIPWDELCNIPKINPFHSFMNIKLAINPWQDLEFKDETIFREQKFFYHIYLLEKSGFLLDNRASKFFQSEKTNSYQIIYSWGKPMFKYAQYIHYTGSCMAEIRESGDFFLAPNNLHISRMNTGNIGSKASSHLKFTSDAQKIMLNFRKTCENYESLRDIFLEAKEKHIDNRVDLDEYTSFQSFNLYT
What are the official names of this protein?
Vacuolar membrane-associated protein IML1.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: DPO3X_MYCTO
Sequence: MALYRKYRPASFAEVVGQEHVTAPLSVALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTANPCGVCESCVSLAPNAPGSIDVVELDAASHGGVDDTRELRDRAFYAPVQSRYRVFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLLPPRTMRALLARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAADTHVTYTRALGLLGVTDVALIDDAVDALAACDAAALFGAIESVIDGGHDPRRFATDLLERFRDLIVLQSVPDAASRGVVDAPEDALDRMREQAARIGRATLTRYAEVVQAGLGEMRGATAPRLLLEVVCARLLLPSASDAESALLQRVERIETRLDMSIPAPQAVPRPSAAAAEPKHQPAREPRPVLAPTPASSEPTVAAVRSMWPTVRDKVRLRSRTTEVMLAGATVRALEDNTLVLTHESAPLARRLSEQRNADVLAEALKDALGVNWRVRCETGEPAAAASPVGGGANVATAKAVNPAPTANSTQRDEEEHMLAEAGRGDPSPRRDPEEVALELLQNELGARRIDNA
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
What are the official names of this protein?
DNA polymerase III subunit gamma/tau.
What is the protein family that this protein belongs to?
Belongs to the DnaX/STICHEL family.
Protein: RL23_SPHAL
Sequence: MAKAKTVDARHYDVILAPVITEKSTLLSENNAVVFKVARDATKPAIKAAVEALFDVKVVGVNTLVTKGKTKRWKGKPYTRSDVKKAIVRLAEGQSIDVTTGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SPOT_BORBU
Sequence: MIQAYEIAHLIKINDLEKARNIFKKTVENTYKDEFERKSIFKALEIAEQLHYGQYRESGEPYIIHPIMVSLFLAKFQLDFKATIAGLLHDVLEDTNVEKEEIVKEFDEEILSLIDGVTKIHDLHNKTRSIKEANTISKMFFAMTHDIRIIIIKLADKLHNMTTLSYLPKNRQDRIAKDCLSTYVPIAERLGISSLKTYLEDLSFKHLYPKDYKEIKNFLSETKIEREKKLYKGKLSIEKELQKSGIEAEITVRSKHFYSIFRKMQTRTNKLTQIFDTLGIRIICKKQKECYEILEIVHRVWKPIPGRLKDYIASPKENKYQSLHTTVRIPEDNQLIEIQIRTEEMDRIANYGVAAHWIYKEQIELKADDLSFINRIKKWQQESANKSQYSMNDIHKELLNTFIYVYTPEGEVVELPFGSNSIDFAYIIHTDIGDQALYAKINGKISSITKPLKNEQIVEIFTSKDSKPDVIWLNSVRTKKARSKIRSWLNKNDNTIFVDNNIIAYLVGANKEQRKLFSLFKSYTKTKIKRIAIDPECSPTTGEDIIGIIHKDEIIVHNENCQKLKSYKKPQLIEVEWEATPTRKVHHIILLLKELKGIFSYLENIFTLNDVRLISEKIEDCGNGHGITNIIVSSNAKNITKIISALKENPNILQIMQIEEDIKNYDN
What is the function of this protein?
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  This enzyme catalyzes the degradation of ppGpp into GDP.  It may also be capable of catalyzing the synthesis of ppGpp (By similarity).
What are the official names of this protein?
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase, Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: MED15_AEDAE
Sequence: MAEDNSWKTPSFRQSVVNKINEAIQQSGMTSSKNGLEMENHVFQKARNKDEYLGYVARLILHVREMNTKNKNQQNPAGGSQDGGNPNQQGGMPDPINALQTLATQGTRPQMMGGQMGPGGPMGNQMGGGNASNLLNTLNRPQMPMTGGMANMQGRVGTMGGPNQMGGMMPGQMPQGMPGMPNQMGGAMGPGGMSGGKIVGQMNPMGQMNPMQMGVSGMPQGAGQQQPQQPQGQQGGPGGPNQMNPMGGMGMQVNPGGHMNQNAINQQMNQVGMSSGGNQMGNLGGNSPMNPGNMGIAPNQVIRQQMPPGMNPNQQQLGMAGGQMNQMNQGVGGPGGNLGPVQQQQQPGQVGMAGMGPGGPGNLQQQNNPQQQSQGGPNAAPGQMNQVGGPGGNMQAMGNQGNFVPIGANPMVRKQDMMSGGQVYPGGVVRSVTPNQFLRQSPSPSVPSPAGPGSIGPQSHPGQMIPSPALIPSPSPQVSSNIPAPRNIGQSPGQSLNTPGQAAAPSPLNPQEEHLYKEKYRSLQKYIEPLKRMIAKMEHDDVDKMGKMKRLLDILCNPTCRIPLETLYKCEAALTSQLGTIREPPLNNPLVEAVSANLQSPLGNHTLQRTFRPCLEALFGPDIKNLPTPAKQPRLAIDEPSTSGSTGSQEIPHILQGEIARLDQKFKVSLDPCAIGDTKTIKLICWLDDKHLPCVPPVAVTIPEEYPFTSPSCSLIEQEYNATPFLIQVQKSFLARICKLPEMFSLSHLLDTWEMSVRQACSPNPSLVAPSATSVLLGM
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 15, Mediator complex subunit 15.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 15 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTAP_EMENI
Sequence: MFLRSVSSITKPFRRIESPKQLARRMAVLPDTYADPVRIAVIGGTGLRELPGFTQVASLNIQTPWGTPSSPITILHHTHKDKTVAVAFLSRHGLHHQIAPHEVPARANIAALRSIGVRTIIAFSAVGSLQEEIKPRDFVVPDQVIDRTKGIRPFTFFEGGVVGHVPFGDPFDESVAKIVRACGHSLEGEGVKLHDRGTLICMEGPQFSTRAESKLYRSWGGSVINMSCLPEAKLAREAEIAYQMICMSTDYDCWHESTEDVTVEMVMGNMKANAVNAKHFVTAVLDELADDRNAELVQAKQYAGSVKFGLSTAQANWSPEARERMNWLFPGYFEIDLYIRYLLLIQRDIDLTSWN
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SUCB2_DICDI
Sequence: MSLFNSANKVIGGVLKFNPSKYQVRYLNLHEYQSKSLMDKYGVNTQKWRVVTKASDAIKAASELNGELVVKAQVHAGGRGKGSFIETGFKGGVHLCKTGKEAERLCDEMLGKHLVTKQTTKEGTKVQSVMLAESVDPKRELYFAIVMDRKYGGPVMIASPQGGVDIESVAEETPDLIFKEPIDIVKGIRPEQTKNLAEKLGFTGEKAKIAQQQMENLYQLFIKSDATQVEINPFAETTDGQVICMDAKINFDDNASFRQKEIFEMRDTAEEDPREVEAGKFGLNYIGLDGNIGCMVNGAGLAMATMDIIKLKGGIPANFLDVGGSASEQAVTEAFKILTKDPRVKCLLVNIFGGIMKCDIIASGIVNASKQVGLKIPLVVRLEGTNVNIGKEILEKSGLNITSASDLDDAAIKAVNCLKK
What is the function of this protein?
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial, GTP-specific succinyl-CoA synthetase subunit beta, G-SCS, GTPSCS, Succinyl-CoA synthetase beta-G chain, SCS-betaG.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FLIE_TREPA
Sequence: MTPVGTITNSANVYKVPSLRKVPEIGPVSVESVRQRMRGNTDAVDQAVNKKAMSFEQTLLRAFDQVNQKQQKTAELTEQMIVDPESVDVHDVTVAMAEASMSLKIAQTVIDKVLKSWNDVTTAR
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: SYE_SHEFN
Sequence: MTTKTRFAPSPTGFLHVGGARTALYSWLHARANNGEFVLRIEDTDIERSTQEACDAILDGMNWLGLTWDEGPYYQTKRFDRYNEIIEQMLDKGTAYKCYCSRERIESMREDQAAQGLQQKYDGCCRNLAPRDTDEPFVIRFKNPIEGSVIFDDHVRGRIEISNDMLDDLIIKRTDGVPTYNFCVVVDDWDMGITCVVRGEDHINNTPRQINILKALGAPIPEYAHVSMILGDDGAKLSKRHGAVGVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSMEELKTLFKLDDINKAASAFNTDKLIWLNQHYIKSLDPVYVASHLQWHMDDQKIDTSNGPALTEIVTALSERAKTLKELAASSRYFYEDFDNFDEAQAKKHLRGVALEPLTLFNQKLSELNDWSVENIHNVIEATATELDVGMGKVGMPLRVAVTGAGQSPALDLTLFLIGKERSAQRISKAIEFVADRINS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_BART1
Sequence: MNNLVCPAIAFPSFLDPVIIQLGPITLHWYGLGYVVGILFAWWYAQKLLKKPSLWHKNHPPMTKEKIGDFVVWSAISVVVGGRLGQVLVWDPLYYFSHPSSIIAVWDGGMSFHGGLIGIIIAMILFARKNNINIRSMFDIIAAGAPIGIGIVRICNFINQELWGNATTQPWAVCFPLDPYYLPRHPSQLYEAFMEGFILFMILFIVIFTFKAFKRRGTVSGIFIIGYAIARSISEVYRAPQEDPEWFSTLFHSTGFTYGMALSLPMLLLGFYLLLQAFKDKSTENDTPQRKN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAA_ECO8A
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: O163_CONVC
Sequence: MKLTCVMIVAVLFLTANTFATADDPRNGLRDLFSIAHHEMKNPEASKLNEKCYGFGEACLVLYTDCCGYCVLAVCL
What are the official names of this protein?
Conotoxin Vc6.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DLTE_BACSU
Sequence: MKMTNNTVLITGGSAGIGLELAKRLLELGNEVIICGRSEARLAEAKQQLPNIHTKQCDVADRSQREALYEWALKEYPNLNVLVNNAGIQKEIDFKKGTEELFVDGDEIELNFQAPVHLSALFTPHLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALHSFSLTLRHQLRDTSVEVIEMAPPMVDTGLNQKSRDKQGLTYRGISSEEYVQYFLDGLKEGKQEITNERVEGLRDATRADYDRLFEQMNTQEN
What are the official names of this protein?
Uncharacterized oxidoreductase DltE.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_LEPME
Sequence: MKKEKADKAQEKETDQRKQAIDAALGQIEKQFGKGSIMRLGADTRMAEMNVVSTGSLDLDIALGIGGFPSGRIVEIYGPESSGKTTLTLSAIAETQKKGGIAAFIDAEHALDPSYAKKLGVNVDDLLVAQPDNGEEALEICESLVRSNAIDLIVIDSVAALVPKAEIEGDMGDSHMGLQARLMSQALRKLTGTISKSNTTVIFINQIRMKIGVMFGSPETTTGGNALKFYASIRLDIRRIETLKEKEEPVGNRVRVKVVKNKCAPPFRQAEFDIMYANGINRESSLIDLAVRHDLVAKAGSWYSYGGEKIGQGKEQVKNFFLENPDIAFKIENQVRDLNSLPLMDQSKIQTREVKSIERDPKETKETKSKQPVSFSTEAEVDIAVGE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_CLAM3
Sequence: MAKPRVHEIAAEIGVDSKTALAKLKEMGEFVKGPSSSIEPPVARKLKAALEAAGLTGQAAAPAAAPSSAPRPGARSSAPKPGGRPTPGPQPTAAPEVEAPEASDVPVPAKPLTVAERQAQAEASRKAAAEEKAQAEKSAASATPDAPAAETPSAPRPDAGSAPAPSNGIPRPGIPRPAAPRPGNNPFASNQGMGTKPRPGNNPFASNQGMGQRPAAGAAGPRPAAPRPGSPRPGAPRPGGVGQGARPAGFGQRPAGAGRPGGAPGGAGRPGAPAAGGFQRPAGGFAGRPGGGGRGRGPGGGTAGAFGRGGGKSKSRKSKRTKRAEFELREAPSLGGVSVPRGDGNTIVRLRRGASISDFADKIDASPGNLVTVLFHLGEMATATESLDEATFEVLGTELGYKIQVVSPEDEDRELLEGFDIDLDQELEDEDDDVLEIRPPVVTVMGHVDHGKTRLLDAIRNANVIEGEAGGITQHIGAYQVWAPHEGYERAITFIDTPGHEAFTAMRARGAQVTDIAILVVAADDGIMPQTVEALNHAQAANVPIVVAVNKVDKEGANPAKVRQQLTEYGLVAEEYGGDVMFVDVSALTGKGVEDLLEAVLLTADAGLDLRSNPNKDARGVAIEARLDKGRGAVATVLIQSGTLRVGDAIVAGTAYGRVRAMMDENGDAVHEAYPSRPVQVQGLSSVPGAGDTFLVTEEDRTARQIAEKREAVERNAQLAKARKRISLEDFTRALEEGKVESLNLIIKGDVSGAVEALEESLMKIEVDDSVQLRIIHRGVGAVTESDVNLATIDNAIIIGFNVRPDPKARARAAREGVDIRFYSVIYSALEEIESSLTGMLKPEFEEVQSGVAEIREVFRSSKFGNIAGVIVRSGTITRNAKARVIRDGVVVGDSLAIESLRRFKDDVSEVRTDFEAGIGLGKFNDIQIGDEIETIEMKEKPRV
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTP6_ORYSJ
Sequence: MAAAAGVAAGTGRGSGEGEELLPNAVEGDGGCGGGGTCAGDRPWRLNFDGLRRPEAHQEKPPRRFHDRLGGLVQSPGDDVAEYYQQQSELLEGFNEMDTLTDRGFLPGMSKEECEKVARSEALAIRLSNIANMVLFAAKVYASIRSGSLAIIASTLDSLLDLLSGFILWFTAFSKKTSNPYRYPIGKRRMQPLGILVFASVMATLGLQIILESTRSLFYDGDTFRLTKEQEKWVVDIMLSVTSVKLLLVVYCRSFTNEILAIYTIRTWSMTVLENVHSLVGQSASPEYLQKLTYLCWNHHKAVRHIDTVRAYTFGSHYFVEVDIVLPCDMPLQEAHDIGEAPQEKLESLPEIERAFVHLDYEFTHQPEHARSHDTL
What is the function of this protein?
Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.
What are the official names of this protein?
Metal tolerance protein 6, OsMTP6.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: ATPL_HELPH
Sequence: MKFLALFFLALAGVAFAHDGGMGGMDMIKSYSILGAMIGLGIAAFGGAIGMGNAAAATITGTARNPGVGGKLLTTMFVAMAMIEAQVIYTLVFAIIAIYSNPFLS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDIS_HUMAN
Sequence: MSVLISQSVINYVEEENIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNIDCSHQKSILTQIFGARHLSPTETDGDMLGYDLYSSALADILSEPTMQPPICVGLYAQWGSGKSFLLKKLEDEMKTFAGQQIEPLFQFSWLIVFLTLLLCGGLGLLFAFTVHPNLGIAVSLSFLALLYIFFIVIYFGGRREGESWNWAWVLSTRLARHIGYLELLLKLMFVNPPELPEQTTKALPVRFLFTDYNRLSSVGGETSLAEMIATLSDACEREFGFLATRLFRVFKTEDTQGKKKWKKTCCLPSFVIFLFIIGCIISGITLLAIFRVDPKHLTVNAVLISIASVVGLAFVLNCRTWWQVLDSLLNSQRKRLHNAASKLHKLKSEGFMKVLKCEVELMARMAKTIDSFTQNQTRLVVIIDGLDACEQDKVLQMLDTVRVLFSKGPFIAIFASDPHIIIKAINQNLNSVLRDSNINGHDYMRNIVHLPVFLNSRGLSNARKFLVTSATNGDVPCSDTTGIQEDADRRVSQNSLGEMTKLGSKTALNRRDTYRRRQMQRTITRQMSFDLTKLLVTEDWFSDISPQTMRRLLNIVSVTGRLLRANQISFNWDRLASWINLTEQWPYRTSWLILYLEETEGIPDQMTLKTIYERISKNIPTTKDVEPLLEIDGDIRNFEVFLSSRTPVLVARDVKVFLPCTVNLDPKLREIIADVRAAREQISIGGLAYPPLPLHEGPPRAPSGYSQPPSVCSSTSFNGPFAGGVVSPQPHSSYYSGMTGPQHPFYNRPFFAPYLYTPRYYPGGSQHLISRPSVKTSLPRDQNNGLEVIKEDAAEGLSSPTDSSRGSGPAPGPVVLLNSLNVDAVCEKLKQIEGLDQSMLPQYCTTIKKANINGRVLAQCNIDELKKEMNMNFGDWHLFRSTVLEMRNAESHVVPEDPRFLSESSSGPAPHGEPARRASHNELPHTELSSQTPYTLNFSFEELNTLGLDEGAPRHSNLSWQSQTRRTPSLSSLNSQDSSIEISKLTDKVQAEYRDAYREYIAQMSQLEGGPGSTTISGRSSPHSTYYMGQSSSGGSIHSNLEQEKGKDSEPKPDDGRKSFLMKRGDVIDYSSSGVSTNDASPLDPITEEDEKSDQSGSKLLPGKKSSERSSLFQTDLKLKGSGLRYQKLPSDEDESGTEESDNTPLLKDDKDRKAEGKVERVPKSPEHSAEPIRTFIKAKEYLSDALLDKKDSSDSGVRSSESSPNHSLHNEVADDSQLEKANLIELEDDSHSGKRGIPHSLSGLQDPIIARMSICSEDKKSPSECSLIASSPEENWPACQKAYNLNRTPSTVTLNNNSAPANRANQNFDEMEGIRETSQVILRPSSSPNPTTIQNENLKSMTHKRSQRSSYTRLSKDPPELHAAASSESTGFGEERESIL
What is the function of this protein?
Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism.  Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation.  May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4.  In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation.  Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.  May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity).  Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
What are the official names of this protein?
Kinase D-interacting substrate of 220 kDa, Ankyrin repeat-rich membrane-spanning protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Late endosome. Note=Localized at late endosome before or after nerve growth factor (NGF) stimulation.
Protein: NUOB_PELUB
Sequence: MNLENKNKEIPEEFKKLAEDFSKNGFITTSLDNLINWSRAGSLHWMTFGLACCAVEMMQTAMPRYDLERFGAAPRGSPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDKIVPVDIYVPGCPPSAEALLYGILQLQKKIRNKGSFER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACHB2_RAT
Sequence: MAGHSNSMALFSFSLLWLCSGVLGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEDFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSDVASLDDFTPSGEWDIIALPGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPTLLFLQQPRHRCARQRLRLRRRQREREGAGALFFREGPAADPCTCFVNPASVQGLAGAFRAEPTAAGPGRSVGPCSCGLREAVDGVRFIADHMRSEDDDQSVREDWKYVAMVIDRLFLWIFVFVCVFGTVGMFLQPLFQNYTATTFLHPDHSAPSSK
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit beta-2, Neuronal acetylcholine receptor non-alpha-1 chain, N-alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-2/CHRNB2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RNP2_SULTO
Sequence: MVIFSYRTRIIYIKKIKNKRDTRAKRYVIFDIISEDNFEIREIEEAVRNSVKELGGKIWLDLSNPKVIMIYNNRGIISTNRIGYKIIIASLPLIKKIKNKEVLLVPRRTTGSLKRAKRLIGIE
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_XANAC
Sequence: MSKRIYSRIAGTGSYLPEKVLTNDDMSKIVDTSDEWIFSRTGIRERHIVADDQTTSDLAYFASLRAMEAAGVTADEIDLIVIGTTTPDLIFPSTACLLQARLGNIGCGAMDVNAACSGFVYALSVADKFVRSGDAKTVLVVGAETLTRIVDWTDRTTCVLFGDGAGAVILKADEETGILSTHLHADGSKKELLWDPVGVSVGFGEGKNGGGALLMKGNDVFKYAVKALDSVVDETLAASGYDKHDLDWLIPHQANLRIIEATAKRMELPMEQVVVTVDRHGNTSSASVPLALDEAVRSGRVQRGQLLLLEAFGGGFTWGSALLRY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.