PharMolix/UniProtQA huggingface dataset:
Protein: RAB2B_HUMAN
Sequence: MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between active GTP-bound and inactive GDP-bound states.  In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology.  Regulates the compacted morphology of the Golgi (Probable).  Promotes cytosolic DNA-induced innate immune responses.  Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis (By similarity).
What are the official names of this protein?
Ras-related protein Rab-2B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid.
Protein: LIPA_MYCBO
Sequence: MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQARNSRALASR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUR_PSEPU
Sequence: MVENSELRKAGLKVTLPRVKILQMLDSTEQRHMSAEECIKALMEAGEDVGLATVYRVLTQFEAAGLVVRHNFDGGHAVFELADGGHHDHMVNVETSEVIEFMDAEIEKRQREIVAEHGFELVDHNLVLYVRKKK
What is the function of this protein?
Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon.  Involved in the siderophore pyoverdine (pseudobactin) 358 biosynthesis regulation.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1209_ORYSJ
Sequence: MDVSRIRFFRLMTGDFAHGISIPEKVAEIFSGQITKGFNLKSPSGETWRVGVAKVADELILKSGWEDFAKAHELQENDLLFFTCNGHGNGSCSFDVLIFDASGCEKVSCFFTGKKNSYMCKNFNSIGGQVAGQYLSSDSEDTSTPSVLIGSPHKASTSKKLSGKTKTNPRKEPEDPNCSHWHVIEEKNTDDDEHADYHYTRFANYLTGEERDEIFSLVSLQPGNPVFVVVLQTAHVRRRNILIVPTRFAADHLERKSHDILLIRPNRKQKWSVKYYYLSNTTRGFNCHRWIKFIRENRLREGNVCIFELMKGARRPTMTVHVIGKADNRFVLLG
What are the official names of this protein?
B3 domain-containing protein LOC_Os12g40090.
What are the subcellular locations of this protein?
Nucleus.
Protein: GTPBA_BOVIN
Sequence: MVRCSCVLFRKYGNFIDNLRLFTKGGSGGMGYPRLGGEGGKGGDVWVVAHNRMTLKQLKDKYPQKRFVAGEGANSRVSALKGSKGKDCEIPVPVGVSVTDENGKIIGELNKEKDRLLVAEGGLGGKLLTNFLPLKGQKRVIHLDLKLIADIGLVGFPNAGKSSLLSKISHAKPAIADYAFTTIKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTKQLLFVVDISGFQLSSQTHYRTAFETIILLSKELELYKEELHTKPALLAVNKMDLPDAQGKFHVLMNQLQNPKEFFHLFEKNMIPERTVEFQHIIPISAITGEGIDELKNCIRKSLDEHTNQENDAYHKKQLLNLHISNTVSYSEPPSKTAVSSPRMDIT
What is the function of this protein?
May be involved in the ribosome maturation process.
What are the official names of this protein?
GTP-binding protein 10.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Found in the dense fibrillar compartment region of the nucleolus.
Protein: FDL40_ARATH
Sequence: MEAARSGIEDVTSPDRISQLPNDLLFRILSLIPVSDAMSTSLLSKRWKSVWKMLPTLVYNENSCSNIGSLGFDQFCGRSLQLHEAPLLKTLTLELRKQTDSLDSSIFPNIHSTLLEFSIKSTGYPVYYSTISFPNNLDVFQTLVVLKLQGNICLDVVDSPVCFQSLKSLYLTCVNFENEESFSKLLSACPVLEDLFLQRLCSVGRFLFSISVPSLQRLTYTKEQAYYSNDEAILEITAPSLKHLNIFDRVGVFSFIEDMPKLVEASVRVKLSKNEKLPKVLTSVEHLSLDLYPSMVFHLDDRFISKQLLHLKLDIYDNFQSNLLLSLLKDLPNLQSLKLNHSHPSYNVEDQPCSVSEPSSVPECLSFHLETFQWIGYAGTFEEIAAAVYVLKNARCLKNATISLYSRGTENGLMMIKELESMSKGSIMCQLLVKF
What are the official names of this protein?
Putative F-box/FBD/LRR-repeat protein At5g56810.
Protein: VL1_HPV29
Sequence: MALWRSSDNLVYLPPTPVSKVISTDDYVTRTNIYYYAGSSRLLTVGHPHYSIPKSSGNKVDVPKVSAFQYRVFRVRLPDPNKFGLPDARIYNPEAERLVWACTGVEVGRGQPLGVGLSGHPLYNKLNDTENSNIAHAENGQDSRDNIAVDYKQTQLCILGCTPPMGEHWGKGTVCARTSSAAGDCPPLELMTTHIEDGDMVDTGYGAMDFAALQVNKSDVPLDICQSTCKYPDYLGMAADPYGDSMFFFLRREQLFARHFFNRAGVVGDKIPDSLYLKGNNGRETPGSAIYSPTPSGSMVTSEAQIFNKPYWLQQAQGHNNGICWANQVFLTVVDTTRSTNMSLCATTESQPLTTYDATKIKEYLRHGEEYDLQFIFQLCKVTLTPEIMAYLHTMNSALLEDWNFGLTLPPSTSLEDTYRFVTSSAITCQKDLAPTEKQDPYAKLNFWDVDLKDRFTLDLSQFPLGRKFLLQIGARRRSVVPSRKRRTTTTAPTPAKRKRSKK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DTD_CHRSD
Sequence: MRAVIQRVRHAGVDVDARTTGAIEQGLMVLVGVAPDDTQTRADKMLHKLLGLRVFSDEAGKMNLNVQQVEGGLLLVPQFTLMANTTKGLRPGFDGAAPPAHGEALFDYLVAQARHAWPYVATGEFGADMQVSLLNDGPVTFIVET
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIFE2_HAEIF
Sequence: MNKKSYINHYLTLFKVTTLLFTLSSNPVWANIKTVQGTTSGFPLLTRTFTFNGNLQWNVSALQPAYIVSSQARDNLDTVHIQSSEINAPTNSLAPFNNWINTKSAVELGYSFAGITCTSNPCPTMKLPLLFHPDLTNLTPPGKKNSDGGEIFKLHNESNLGVSFQIGVKTNTSLDWVNAKNNFSSLKVLMVPFNSSDKISLHLRAKFHLLTDFSSLNNDITIDPMNTSIGKINLETWRGSTGNFSVKYVGEDKGDISIFFNTPKIILKKQQRRCTLNNAPVSPNPVKLRAVKKRELEAQSEMEGGTFQLRVNCDNTTYNKANGKWLFPVVKVTFTDEDGTTNNGTNDLLRTQTGSGQATGVSLRIKRENGTETVKYGADSAQMGNAGQFELRKQPSPAGGDQYAEETFKVYYVKDSTRGTLIEGKVKAAATFTMSYQ
What is the function of this protein?
May be a minor structural protein required for pilus biogenesis.  May be the adhesive component in the pili.
What are the official names of this protein?
Minor fimbrial subunit HifE.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: AGLU_ASPOR
Sequence: MAGLKSFLASSWLLPVACGASQSIVPSTSATAAYSQFTIPASADVGANLVANIDDPQAVNAQSVCPGYKASDVKHSSQGFTASLELAGDPCNVYGTDVDSLTLTVEYQAKDRLNIQIVPTYFDASNASWYILSEELVPRPKASQNASVPQSDFVVSWSNEPSFNFKVIRKATGDVLFNTKGSTLVYENQFIEFVTLLPEEYNLYGLGERMNQLRLLENANLTLYAADIADPIDDNIYGHHAFYLDTRYYKVGGQNKSHTIVKSSEAEPSQEYVSYSHGVFLRNAHGQEILLRDQKLIWRTLGGSVDLTFYSGPTQAEVTKQYQLSTVGLPAMQQYNTLGFHQCRWGYNNWSEFEDVLANFERFEIPLEYLWADIDYMHGYRNFDNDQHRFSYEEGEKFLNKLHAGGRRWVPIVDGALYIPNPENASDAYETYDRGAKDDVFIKNPDGSLYIGAVWPGYTVYPDWHHPKASDFWANELVTWWNKLHYDGVWYDMAEVSSFCVGSCGTGNLSMNPAHPPFALPGEPGNVVYDYPEGFNITNATEAASASAGAASQSAAASSTTTSAPYLRTTPTPGVRNVDHPPYVINHVQPGHDLSVHAISPNSTHSDGVQEYDVHSLYGHQGINATYHGLLKVWENKRPFIIARSTFSGSGKWAGHWGGDNFSKWGSMFFSISQALQFSLFGIPMFGVDTCGFNGNTDEELCNRWMQLSAFFPFYRNHNVLSAIPQEPYRWASVIDATKAAMNIRYAILPYFYTLFHLAHTTGSTVMRALAWEFPNDPSLAAVGTQFLVGPSVMVIPVLEPQVDTVQGVFPGVGHGEVWYDWYSQTAVDAKPGVNTTISAPLGHIPVFVRGGSILPMQEVALTTRDARKTPWSLLASLSSNGTASGQLYLDDGESVYPEDTLSVDFLASRSTLRASARGTWKEANPLANVTVLGVTEKPSSVTLNGETLSSDSVKYNATSHVLHVGGLQKHTADGAWAKDWVLKW
What is the function of this protein?
Hydrolyzes malto-oligosaccharides, but has a low activity toward soluble starch.
What are the official names of this protein?
Alpha-glucosidase, AGL, Maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
Protein: RL27_METCA
Sequence: MAHKKAGGSSRNGRDSESKRLGVKRFGGQVVRAGNIIVRQRGTHFHPGDNVGCGRDYTLFALTEGRVEFKVKGPAGRKYVSVIPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CLU_DROPE
Sequence: MALEMDSKNSNSAVTGDAAAATTKTNKAKENNNLAGSKKNQSQNLVNGNGTAADGPATKKKGKKNRNKSPPVSTDEAALSNGHVEEKKPEGDGDADADANANVVAVKDEKAEGGDEADAAELDTEDIDLDALHDAGIHVNISCPGSELLTVQLSSMELVQEIHQLLMDREESCHRTCFSLQLDNVTLDNFAELKTIEQLESGSTIKVVEEPYTMREARIHVRHVRDLLKNLDPADAYNGIECTSLTYLNTITQGDLLDKKKTRPDSVDCTPPDYVTPGVFEPPLLPLHPNFKNAKGPQALKVLTTSAWNPPPGPRKLHGDLMYLYVITMEEKRYHISACSRGFFINQSTDDTFNPKPDNPSYLSHSLIDLLSHISPSFRRAFQAIQKRRTLRHAFERVATPYQVYQWAAPNLEHTVDAIRAEDAFSSKLGYEEHIPGQTRDWNEELQTTRELPRKTLPERLLRERAIFKVHGDFVTAATRGAMAVIDGNVLAINPGEDSKMQMFIWNNIFFSLGFDVRDHYKELGGDYAAYVAPRYDLHGVRVYNAVDVEGLYTLGTVVIDYRGYRVTAQSIIPGILEREQEQSVVYGSIDFGKTVLSHPKYLELLRQAGKHLKILPHSVYNERDEPVELCSSVECKGIIGNDGRHYILDLLRTFPPDVNFLKLQEVKLSTELVEMGFPIEHRHKLCCLRQELLEAFVEDRYVNFIRIAAVHLQQLNAKKPEETQSEEKKQLPAIEEAEKENKENLNVNETPNEKEKDTPVETKNAEAMVNAIREAQSNVATSNEIQAAEVVKQACAAVGSMKEKEFDFRFNPDVFSPGIRHVDGEEGTSGSVAKQKLLVQDAAEFLVVKQIPAFVKEHLSHSSPPIDGQNLTESLHSHGINVRYLGKVIKTLGQMPRMDYLYRIAVMELIVRATKHIYYTYMQSTDPMHLSVAISHFLNCLLTNGPINPVVSNDEMHKKRGGNGGKHNKHKSSKGGKGQQQPAINQNGGSTTSSSSSANAYDWTLVTPRSLWQQIRKESKAYWDWDLDCDSMDSAMNKFGIMRICLLRAFCLKVGIQVLLREYNFDSKHKPTFGDDDIVNVFPVVKHISPRASDAYNFYTTGQAKIQQGLFKEGYELISEALNLLNNVFGAMHQENGSCLRMLARLSYLLGDAQDALAIQQRAVIMSERVNGIDNPSTILEYTHLSLYSFANGHVGMSLKLLYRARYLLVLTCGEDHPEVALIDSNISLILHALGEYELSLRFIEHALKLNLKYFGNKAMHVAVSYHLMARTQSCMGDFRSALNNEKETYSIYKSQLGEKHEKTRDSAECLRLLTQQAVLLQRKMNDIYSNGKLTSDLPPIHITPPSMGSVLEMLNTINGILFVQISQRDIVKVRSEIEKRMKANTDVNEAIKSMVAAANNNGESEVLAPQDNNKEQAATAQQLTNGDKVAVSS
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Protein clueless, Clustered mitochondria protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_AERS4
Sequence: MWIGVISLFPEMFRAITEHGVTGRAVKSGLLQIECWNPREFTHDKHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKQAAGDGAKVIYLSPQGRKLTQAGVTELATNQKLILVAGRYEGIDERVIQTEVDEEWSIGDYVLSGGELPAMTLIDAVSRLVPGVLGDQASAEQDSFTDGLLDHPHYTRPELLDGLAVPEALTSGNHEVIRRWRLKQSLGRTWQRRPELINNLALTDEQESLLAEYVREVRDSVK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR6_OGAME
Sequence: MDSQTVGILGGGQLGRMIVEAAHRLNIKTVILENGDQAPAKQINALDDHIDGSFNDPKAIAELAAKCDVLTVEIEHVDTDALVEVQKATGIKIFPSPETISLIKDKYLQKEHLIKNGIAVAESCSVESSAASLEEVGAKYGFPYMLKSRTMAYDGRGNFVVKDKSYIPEALKVLDDRPLYAEKWAPFSKELAVMVVRSIDGQVYSYPTVETIHQNNICHTVFAPARVNDTVQKKAQILADNAVKSFPGAGIFGVEMFLLQNGDLLVNEIAPRPHNSGHYTIDACVTSQFEAHVRAITGLPMPKNFTCLSTPSTQAIMLNVLGGDEQNGEFKMCKRALETPHASVYLYGKTTRPGRKMGHINIVSQSMTDCERRLHYIEGTTNSIPLEEQYTTDSIPGTSSKPLVGVIMGSDSDLPVMSLGCNILKQFNVPFEVTIVSAHRTPQRMAKYAIDAPKRGLKCIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGIPVATVAINNATNAALLAITILGAGDPNTCLQWKFI
What are the official names of this protein?
Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.
Protein: Y198_RICPR
Sequence: MIRKILLLVFLAFTIIWFATAYTIKNNIVNLIKNSESDNLRIYYNAIKFSGYPFNWKINITDPKVKLIDHINSKEFICKNIVIDISFSTKRATLNFGPFIQIDNYGDKPFTYNVHSDNNINGISKFNKPLYKVSQDDSLKEILKSIKLNNKTLSIFKDNQEIFKINDLAFLIKKHNLASQENISLFLNMHYYSEKDILNFKNANLDMATSFKFAKNGKDAAILENLNIERFIFTCDNESKVNLNGTLQFFANKLPKGILSFELENYNSIVDKLLPNSILFSKKTIKTIIAKAMNKTSDEQLNTDKNDTNSVYNNIKNAKFDIAFSDKGINIGSMNLLELTLGEYKAEKNTENNPN
What are the official names of this protein?
Uncharacterized protein RP198.
Protein: TPP7_ORYSJ
Sequence: MAKASVVVPEQVGAAAAAQVGCPCPGTTLFPYPPPRAGIAVRRKCLQAAQQLELGAGLRGGWVESMRASSPTHAKAAAALAAGVDEEHAAWMARHPSALGEFEKVVAASKGKQIVMFLDYDGTLSPIVDDPDAAFMSETMRMAVRSVAKHFPTAIVSGRCRDKVFEFVKLAELYYAGSHGMDIKGPASRHAAAKSPPHNKGVLFQPASEFLPMIEQVHQRLEQATSSIPGAKVENNKFCVSVHFRCVDEKSWGALAETVRRVVREFPRLRLSQGRMVFEVRPTIKWDKGKALEFLLDSLGFADCSDVLPVYIGDDRTDEDAFKVLRRRGQGVGILVSKHPKETSASFSLQEPAEVMEFLLRLVEWNRLSRTRLRL
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.  Trehalose accumulation in plant may improve abiotic stress tolerance (By similarity).
What are the official names of this protein?
Probable trehalose-phosphate phosphatase 7, OsTPP7, Trehalose 6-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: CH60_PEDPA
Sequence: MAKEIKFSEDARTKMLKGVDKLADTVKSTIGPKGRNVVLEQSYGSPTITNDGVTIAKAIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVNEGMKNVTAGANPVGIRRGIEKATSKAVEALHKMSHEVKTKDDIAQIASISSANPEVGKLIANAMEKVGNDGVITIEESRGVDTTLDVVEGMQFDRGYMSQYMVTDNDKMEANLDNPYILITDKKIGNIQDILPVLQSVVEQSRSLLIIADDITGEALPTLVLNKMRGTFNVVAVKAPGFGDRRKEQLEDIAILTGGTVITDDLGLNLKDVTIEQLGQSNKVTVTKDDTTIVEGAGSQEQIAERVGIIKQQISETTSDFDKEKLQERLAKLSGGVAVIRVGAATETELKEKKYRIEDALNATRAAVEEGFVPGGGTALANVISDLEDVEAEGDEATGVNIVRRALEEPVRQIAENAGEEGSVIVTKLKGQKPGVGYNAANDEWVDMVEAGIVDPTKVTRSALQNAASVSALLLTTEAVVADLPEDNPAPAAPAPGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_SALAR
Sequence: MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDDDVDADEGVGEVRVHRVNHAPGQPQEHDAPRQSPQHQYQPPYASAQPRPATPPQPQAPQQQPVQQPPQPVPPPQQVQPSAPPVQPQQPAQPSQAPQPVAQPAPPLAEQTFQPADPAVEAEPVVEEAPVVEKPQRKEVVIIMNVAAHHGSELNGEVLLNSIQQSGFKFGDMNIFHRHLSPDGSGPALFSLANMVNPGTFDPEMTDFTTPGVTIFMQVPSYGDALQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDRIREVMDANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: MINP1_DROME
Sequence: MRLLILLLLPLVAIAQDDYCFSKDTSRLQTRQFSSKTAYQIVKGTDIDKQYLVPGCQPQKMWIFHRHGTRLPKKSMINKASRVAELRDLIINNYQVARTKPETDALCQTDLIAIKLWKWNSSITPDMEEYLTAQGYEDLRGTAKLYQRYYPTVLTANYNDTYYQFRHTDTQRTTESFKAFAEGLFGSQNAAHPVEIPKQDLLLRPYDYCSSFKNVNYKDEGSEYYKFHQSKLYNDTLADISTRLGFLYTLEEADIKLMYDMCRYEQAWNVDRNSVWCGAFLPEQITVFEYLEDLKYYYGSGYGFPENAHLNCRLVQDLLTHLSNPVSPHVVAHFGHSTGLLTLLTALGIQKDDIKLRADNYDSLTSRRWKSSLIDPFAANFVAVKYDCPADLDREKVVFFLNQQAVQLDWCSVGLCKWSDVLEKYKTIADADCGEYYCRTGGAPSLGSGVGGLLATTLAAMLVYLMH
What is the function of this protein?
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) (PubMed:26628373).  Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate (By similarity).  Has a role in embryonic tracheal development where it localizes to the leading edge of actively migrating branches (PubMed:26628373).  In these leading cells, enhances formation and/or maintenance of filopodia which may drive branch migration and elongation by cell-cell intercalation (PubMed:26628373).  The function in tracheal morphogenesis is dependent on its inositol polyphosphate phosphatase activity (PubMed:26628373).
What are the official names of this protein?
Multiple inositol polyphosphate phosphatase 1, 2,3-bisphosphoglycerate 3-phosphatase, 2,3-BPG phosphatase, Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase, Ins(1,3,4,5)P(4) 3-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family. MINPP1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Basolateral cell membrane. Cell projection, filopodium. Cell junction. Note=Has a dynamic localization pattern during tracheal development. During early tracheal invagination (embryonic stage 10), localizes mainly to the apical cell membrane. During the primary tracheal branching stage (embryonic stage 11), found mainly at the basolateral cell membrane. At later stages (embryonic stage 13-15), also localizes to cell-cell junctions and filopodia.
Protein: SYM_PSEF5
Sequence: MSEPRKILVTSALPYANGSIHLGHMLEYIQTDMWVRFQKLRGNQCIYVCADDAHGSAIMLRAEKEGITPEQLIANVQAEHCADFAEFLVDFDNFHSTHAEENRELSSQIYLKLRDAGHIATRSITQYFDPEKKMFLADRFIKGTCPKCGTEDQYGDNCEKCGATYAPTDLKDPKSAISGATPVLKDSQHFFFKLPDFQQMLQSWTRSGTLQDAVANKIAEWLDAGLQQWDISRDAPYFGFEIPDEPGKYFYVWLDAPIGYMASFKNLCSRRPELDFDAFWGKDSTAELYHFIGKDIVNFHALFWPAMLEGAGYRKPTGINVHGYLTVNGQKMSKSRGTFIKARTYLEHLSPEYLRYYYASKLGRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNAGVMVDSNAAPELTEAFLAAAPSIADAYEARDFARAMREIMGLADRANAWIADKAPWSLNKQEGKQDEVQAICATGIILFRQLVIFLKPVLPLLAADAEAFLNVAPLTWNDHQQLLANHQLNKFKPLMTRIDPVKVQAMTDASKEDLAASQTDTGGPKGNGELVKDPLSAEIDFDAFAAIDLRVALIVKAEAVEGADKLLRLTLDIGDEQRNVFSGIKSAYPDPSKLDGRLTMMIANLKPRKMKFGISEGMVMAAGPGGEEIYLLSPDSGAKPGQRIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPB_STAAR
Sequence: MSNNKKHQNHEHHSHQEHENHTSHGNHEHHHHGNFKSKFFISLIFAIPIIILSPMMGVKLPFQISFTGSDWIVLILATILFFYGGKPFLSGAKDEISTKKPGMMTLVALGISVAYIYSLYAFYMNNFSGSSTHTMDFFWELATLILIMLLGHWIEMNAVGNAGNALKKMAELLPNTAVKLIDNNQREEVKISDIHIDDIVEVRAGESIPTDGIIVRGETSIDESLVTGESKKVHKTHNDDVIGGSINGSGTVQVKVTATGENGYLSQVMGLVNQAQNDKSKAELLSDKVAGYLFYFAVSIGLISFIVWMLIQNNVDFALERLVTVLVIACPHALGLAIPLVTARSTSIGAHNGLIIKNRESVEIAQHIDYIMMDKTGTLTEGNFSVNHYESFTDELNNEEILSLFASLESNSNHPLATGIVDFAKGKNISYATPQEVNNIPGVGLEGTVDNKKLKIVNVSYLDKSNFDYNKEQFTNLAQQGNSISYLIHDRQVIGIIAQGDKIKESSKQMVSDLLSRNITPVMLTGDNKEVAQTVAEELGISDVHAQLMPEDKESIIQDYQSNGSKIMMVGDGINDAPSLIRADIGMAIGAGTDVAIESGDVILVKSNPSDIINFLSLSKNTMKKMVQNLWWGAGYNVIAVPLAAGILASIGLILSPAVGAILMSLSTIIVAINAFTLKLK
What is the function of this protein?
Involved in copper transport.
What are the official names of this protein?
Probable copper-transporting P-type ATPase B.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GA45A_BOVIN
Sequence: MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDIDILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
What is the function of this protein?
Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.  In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity).
What are the official names of this protein?
Growth arrest and DNA damage-inducible protein GADD45 alpha.
What is the protein family that this protein belongs to?
Belongs to the GADD45 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECF_ECO55
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIBA_URSAR
Sequence: TDGKEGEFIAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.