PharMolix/UniProtQA huggingface dataset:
Protein: LEXA_THENN
Sequence: MKDLTAKQRSVLIFIEEFIEKNGYPPSVREIARRFRITPRGAQLHLVALEKKGYIERKNGKPRAMRVTKSVKNRVPLIGEIRAGEKKEAIEYLEDYIEVPGSFLSSGYEHFLLRVKGESMIEEHICDGDLVLIRRQDWAQNGDIVAAMVEGEVTLKKFFQRGEMVELRPANKEMSPMFFRADRVKILGKVVGVFRKYEGGRTCFLTR
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RRT1_YEAST
Sequence: MILFKNLVFLPSILIGYISIRVSLLVWVNWVLVWSSCFQVAFIFSLWYFILSIYTFFYSKKIKQIISYEPSYFVFSYRAIDLCPERVLLYFFCIFNNVVFPML
What is the function of this protein?
Identified in a screen for mutants with decreased levels of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription protein 1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TVC1_MOUSE
Sequence: MLLLRWFTSCCLWVFGLGQLEQTELSVTRETDENVQISCIVYLPYFSNTAIHWYRQKTNQQFEYLIYVATNYNQRPLGGKHKKIEASKDFKSSTSTLEINYLKKEDEATYYCAVWMRWSSGFHKVFAEGTKLIVI
What are the official names of this protein?
T-cell receptor gamma chain V region V108A.
Protein: DBP3_COCIM
Sequence: MAKRPLQTEANVERLPSELKRRKKKNSLKVTPGTVIGQNSKSRRNVPGMDDGNDKRASDSRYLPTPELSALPQSTIDEYLSSNSIHIADPSTDPSLRPITSFSFLPESSNDLYLPLEKFSSPTPIQAVSWPLAFAGRDLIGVAETGSGKTLAFGLPCLRRVLELNNSETSCKPCALIITPTRELAVQIYDQLLRFSSAVDVGIACIYGGSPKDHQRREIRNASVVIATPGRLKDFQADQTINLSGVKYLVLDEADRMLDKGFEQDIQDIVKGIPSTQKRQTIMFTATWPIGVRNLAASFTKNPVTVTIGDSSDIRANKRIKQMVEVLQPYEKDSRLLELLRRYQDGGKNNHRILVFCLYKKEAMRVERFIGSKGFKVAGIHGDMSQTERFRSLEAFKSGSISLLVATDVAARGLDIPAVKLVLNVTFPLTIEDYVHRIGRTGRAGAEGLAITLFTERDKALSGPLINVLRAADQDVPESLLKFGATVKKKQHESYGAFFREMDTTKVASRIKFED
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TBC25_MOUSE
Sequence: MRPPAQARWEGQGPTAPLRLRSGARWGRGRPHCWVYVRVRVTIGYHLDRDDSGGMATTSAASDSACSAAPPPVGGAQAAAAVEEEEREVVRVRVKKCESFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQETFLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVADTGFGSHRGRPVRQRHMLRPAGGGGGAFEDAVVHLAASSQGPSGGGRLLRQASLDGLQQLRDNMGLRKDHLVQLSHPATLISSKSLSEPLLNSPDPLLSTSSRPDSPSSSSPPSTQEASPSGDIAVGSPLMQEVGSPRDPGKPVPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS
What is the function of this protein?
Acts as a GTPase-activating protein specific for RAB33B.  Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes.
What are the official names of this protein?
TBC1 domain family member 25.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, autophagosome. Note=It is dispersed in the cytoplasm under nutrient-rich conditions.
Protein: RL27_ACISJ
Sequence: MAQKKGGGSTRNGRDSKPKMLGVKAYGGELISAGSIIVRQRGTRIHPGVNVGVGKDHTLFALVDGHVSFGTKGALSKHTVSVTPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PANC_AERS4
Sequence: MLVVNNPLVLREQISLWRREGRSIAFVPTMGNLHQGHLTLVEQARSHAEKVVVSIFVNPMQFDKAEDLANYPRTLEEDCAALNAAGVDLVFTPTPEIMYPQGLASQTFVEVPGLSGLLEGALRPGHFRGVSTVVTKLFNLVQPDVACFGQKDYQQLALIRKMVADMAMPIEIVGVPTVRAEDGLALSSRNGYLTTAERALAPELARTMNWIAEQIEGGDHHLPSLVAQASQRLDNAGFRTDAIDIVDATTLESATDKSRHLVILMAAYLGKARLIDNRVVMLSA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_CHRSD
Sequence: MGQKVNPTGIRLGIVKDHRSVWYAERGAYADKLNNDLEVRRFLEQRLKNASVSDITIERPANNARITIHTARPGIVIGKKGEDVDRLRRDVSEMMGVPVHVNIEEVRKPELDAQLVAQNVCGQLERRVMFRRAMKRAVQNAMRLGAGGIKIQLSGRLGGAEIARTEWYREGRVPLHTLRADIDYATYEAHTTYGVIGVKVWVFKGEILGGIEEVRAKQKQAQAPAPKKKGSR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TACY_LISMO
Sequence: MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE
What is the function of this protein?
A cholesterol-dependent pore-forming toxin, which is a major virulence factor required for the escape of bacteria from phagosomal vacuoles and entry into the host cytosol.  After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex.  Listeriolysin O activates mitogen-activated protein (MAP) kinase activity in host cells, most likely as a result of the permeabilization of the host cell membrane.  Also induces a proteasome-independent degradation of UBE2I (the SUMO-conjugating enzyme UBC9) and a proteasome-dependent degradation of some sumoylated proteins.  Finally, is necessary and sufficient for spacious Listeria-containing phagosomes (SLAPs) formation, suggesting a role for listeriolysin O in promoting L. monocytogenes replication in vacuoles, leading to persistent infection.  Recognized by serum from healthy humans exposed to L. monocytogenes as well from patients who have recovered from listeriosis (PubMed:9284184).
What are the official names of this protein?
Listeriolysin O, LLO, Thiol-activated cytolysin.
What is the protein family that this protein belongs to?
Belongs to the cholesterol-dependent cytolysin family.
What are the subcellular locations of this protein?
Secreted. Host membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein that then inserts into the host membrane and forms pores formed by transmembrane beta-strands.
Protein: DAPB_XYLF2
Sequence: MDSFLRLLIHGASGRMGQSLLRLASEDPSFQVTAAVVGNAPHRHVSDGVPFFAAAELAAVPAFDVAIDFSLPQGFSSLLALCVARAVPLVSGTTGLDSRQHEALVMAGARIPLVWGSNFSVGMAVLVNLVERAGDALSGWDCDIVESHHVHKQDAPSGSALTLGEAVACKGIAPRYTSLRAGDIIGDHLVQFTGLGERIELVHRASNRDVFARGALSVARRVVGRVPGCYRVRDLM
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_NATTJ
Sequence: MAVAKVQYFGTGRRKTSVARVRLVPGNGKIVVNNKAMDDYFGLETLKAIIKQPLQTVEMEDKFDVLVNVRGGGHSGQAEAIRHGIARALVKADGELRPVLKKEGYLTRDPRMKERKKYGLRKARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RL11_SYNJA
Sequence: MAKKLVAVVKLAIQAGKATPAPPIGPALGQHGVNIMAFCKEYNAKTADQAGMVVPVEISIYEDRSFTFVLKTPPASVLIKKALGIESGSSEPHKVKVGSLTRAQLRQIAEQKLPDLNARDVEAAMKIIAGTARSMGVTIVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: TRX1_ALHV1
Sequence: MKTKQDPRDQKNYDSLQSNLFRLIPPTTHKISLARPNGFLRGLADLVGKYSVDGAEESLFQPGAWDAPYVQPAFFDFLVHAKTISKHEPVGVPLFCFKNNSTAPSIDVLFTPISFHAAVGLPADVDPNVHRVAHIWYGDDSEVSSLMEDLNILLEESNLHTRLHPVGILVENNDSSFLNRVTALTHGPAYMSRKQAALKLVIPTDLFVDLDARLNVEAYGAQPSGGTSTVFCTLVYTRCGNDIKPALTFFKSNKSDFDVLTLIRAYYADLITNKLEVNQQCNINGLKFGVMCTVGYTDSSHSINQQSLCIRGSSLLVTSISNFFVNYTGWRVFA
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GLMU_COXB2
Sequence: MGLSVIILAAGQGKRMASSTPKILHPLGGIPLLERVVNTARLLNPHTIQVVYGNGGSHVREKLNYLPVHWIEQSQPLGTGHAVLQAIPFCQNEDRVLILYGDVPLISPKTLNSLLENTPSNGLGVVVAELPDPTGLGRIIRDDFGNILSIVEHKDAAEHQLKIREINTGIMTTTAMNLKKWLPQLNNNNCQKEYYLTDTVALAVAEGCPVGCVAAQCCEEVQGVNDRWELTKLERYYQRLMAKKLSLAGVTIIDPERFDARGENIEIAPDVVIDVNVILEGNVQLDRNVRIGPNVILKNTTVGENTEIHANSVIEAAVIKANCSVGPFARLRPGSVLEEGAKVGNFVEMKKTTLGRGSKANHLTYLGDTIIGKNVNVGAGTITCNYDGANKWQTKIEDGAFIGSNVALVAPLTVGKNATIGAGSTLSQDAPPDQLTVARERQRTIKGWHRPTKKE
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPCF_ELIMR
Sequence: MKYKKLSVAVAAFAFAAVSAQNSNSLKYPETKKVNHTDTYFGNQVSDPYRWLEDDRAEDTKAWVQQEVKFTQDYLAQIPFRGQIKKQLLDIWNYEKISAPFKKGKYTYFYKNDGLQAQSVLYRKDASGKTEVFLDPNKFSDKGTTSLANLSFNKKGTLVAYSISEGGSDWNKIIILDAETKKQIDETLLDVKFSGISWLGDEGFFYSSYDKPKDGSVLSGMTDKHKVYFHKLGTKQSQDELIIGGDKFPRRYLSGYVTEDQRYLVVSAANATNGNELYIKDLKNKTDFIPIITGFESNVGLVDTDGDTLFLHTDKNAPNMRMVKTTIQNPKPETWKDVIAETSEPMRVNSGGGYFFATYMKDALSQIKQYDKTGKLVREIKLPGSGTAGGFGGEKTEKELYYSFTNYITPPTIFKFSIDSGKSEVYQKPKVKFNPENYVSEQVFYTSADGTKIPMMISNKKGLKKDGKNPTILYSYGGFNISLQPAFSVVNAIWMENGGIYAVPNIRGGGEYGKKWHDAGTKQQKKNVFNDFIAAGEYLQKNGYTSKDYMALSGRSNGGLLVGATMTMRPDLAKVAFPGVGVLDMLRYNKFTAGAGWAYDYGTAEDSKEMFEYLKSYSPVHNVKAGTCYPSTMVITSDHDDRVVPAHSFKFGAELQAKQACKNPVLIRIETNAGHGAGRSTEQVVMENADLLSFALYEMGIKNLK
What is the function of this protein?
Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.  Has an absolute requirement for an X-Pro bond in the trans configuration immediately preceding the Pro-Y scissible bond.
What are the official names of this protein?
Prolyl endopeptidase, Post-proline cleaving enzyme, Proline-specific endopeptidase, PE, PSE.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MNMC_HISS2
Sequence: MFTVTPAKIYLNQEKTPVSEQFNDVYFSNQDGLAESEYVFQQGNHLWERWIVYQEKHFVIAETGFGTGLNFLAVTSLFRQFRQQYSHSPLKHLFFISFEKYPLPKVQLQQIHQFYPQFSALSQQLCDYCLEAIQGCQRFHFAETTLDLWFGDIVDNLPQLGDYMQNRIDAWFLDGFSPSKNPQMWNDELYQQMFYYSKPQGTFSTFTAASAVRKGLVSAGFEVQKRKGYGKKRECLCGIKNAIPQQNTKAPWYLSQPASLLSEDIAIIGGGIASLFTALSLLKRGAKITLYCEDEQLALNASGNKQGAFYPQLSDDDDRNIRFYVHAFFYALQQLQWAIKQGIEFEHEFCGVALCAYDHKSAVKLAKISSYQWSKSLYQNLNKEQLSEKIGLPLDCAGGFIPQGGWLAPRQFVQNTFSYLQQLGLEIKTSQKITALDYRNLQWVLTNEQNETFNHQVVVLANGYQITDFVQTAKLPLYPVRGQVSQIPTSANLLKLKSVLCYDGYLTPADKMKQSHCLGASHIRNNKDRHFSHQEQRENQQKIQQNLASTDTDKNMDWLQDIDISANIARIGVRCSVRDRVPIMGNVPHFEQQCLDYRNIFNLRRRKQPIPDAAQWKNLYLIGALGSRGLTSAALLGETLASLIYAEPLPLSEDILHNLSPNRSWIRKLLKGTEIK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO5_ARATH
Sequence: MEITNVMEYEKIAKEKLPKMVYDYYASGAEDQWTLQENRNAFSRILFRPRILIDVSKIDVSTTVLGFNISMPIMIAPTAMQKMAHPDGELATARATSAAGTIMTLSSWATCSVEEVASTGPGIRFFQLYVYKDRNVVIQLVKRAEEAGFKAIALTVDTPRLGRRESDIKNRFALPRGLTLKNFEGLDLGKIDKTNDSGLASYVAGQVDQSLSWKDIKWLQSITSLPILVKGVITAEDARIAVEYGAAGIIVSNHGARQLDYVPATIVALEEVVKAVEGRIPVFLDGGVRRGTDVFKALALGASGVFVGRPSLFSLAADGEAGVRKMLQMLRDEFELTMALSGCRSLREISRTHIKTDWDTPHYLSAKL
What is the function of this protein?
Catalyzes the oxidation of glycolate to glyoxylate, with a reduction of O2 to H2O2.  Is a key enzyme in photorespiration in green plants.
What are the official names of this protein?
Glycolate oxidase 3, GOX 3, AtGLO5, Peroxisomal (S)-2-hydroxy-acid oxidase GLO5, Short chain alpha-hydroxy acid oxidase GLO5.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ARGB_CUTAK
Sequence: MTLALDIPLNDTQFSAQRKSEVLVEALPWIRRFQGRTVVVKYGGNAMVDPGLQQAFADDIVFMASVGIRPIVVHGGGPQINAMLAESATPVEFRNGLRVTSPEVMEVVRMVLVGQVGRQLVNRINAYAPLAAGMSGEDSGLLSARKSRVIVDGEQIDMGLVGDIVDVNIDLVISMLDRGQIPVIAPVSPEVDAAGRPTGQVLNVNADTAATAIAQALRAEKLVMLTNVAGIYGTWPDPHTLISEVSASDLRAMIPRLGEGMRPKAQALLDAIDGGVSSAAIVDGRIEHALLLEIFTTRGVGTMARSDDYV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_SYNS3
Sequence: MELTGSELWDKVQHALQSNLSKPTFETWIRPARCSSFQDRMLTLQAPNSFASNWLRKNYASTIAEVAQEIIGHPIEVIVLAQDDEDAESGSTPLSRVSTSNQPLASTAAEAAAAVSAPPSTAPRRLPGLNMRYVFNRFVVGPNSRMAHAAALAVAEAPGREFNPLFICGGVGLGKTHLMQAIGHYRLEIDPEARVFYVSTETFTNDLITAIRKDGMQAFRDRYRAADLILVDDIQFIEGKEYTQEEFFHTFNALHDAGRQIVIASDRPPSQIPRLQERLISRFSMGLIADIQAPDLETRMAILQKKAEQERVALPRDLIQYISGRFTSNIRELEGALTRAVAFSSITGIPMTVESVAPMLDPSGQGVDVTPQQVIEKVSEVFDVTADDMRSSSRRRAVSQARQVGMFLMRQGTDLSLPRIGDTFGGKDHTTVIYAIEQVEKKLATDPQLASQVQRVKDLLQIDSRRRR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA2_NAJHA
Sequence: LKCHKLVPPFWKTCPEGKNLCYKMYMVATPMLPVKRGCIDVCPKDSALVKYMCCNTDKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 2, Toxin V(II)2/V(II)2A.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: YIPF5_MACFA
Sequence: MSGFENLNTDFYQTSYSIDDQSQQSYDYGGSGGPYSKQYAGYDYSQQGRFVPPDMMQPQQPYTGQIYQPTQAYTPASPQPFYGNSFEDEPPLLEELGINFDHIWQKTLTVLHPLKVADGSIMNETDLAGPMVFCLAFGATLLLAGKIQFGYVYGISAIGCLGMFCLLNLMSMTGVSFGCVASVLGYCLLPMILLSSFAVIFSLQGMVGIILTAGIIGWCSFSASKIFISALAMEGQQLLVAYPCALLYGVFALISVF
What is the function of this protein?
Plays a role in transport between endoplasmic reticulum and Golgi.  In pancreatic beta cells, required to transport proinsulin from endoplasmic reticulum into the Golgi.
What are the official names of this protein?
Protein YIPF5, YIP1 family member 5.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle. Note=Enriched at the endoplasmic reticulum exit sites (By similarity). Incorporated into COPII-coated vesicles (By similarity).
Protein: END4_HALOH
Sequence: MRLGKHVSIAGGLYKATDRATKIGCNALQIFVKNPRGWKIKEVSDSEIKKLKDNIKKENMYPLVVHSSYLINMATPRDELWEKSVNSLKKEYKRTELINADYFVVHPGSHTGKGLHFGINRIIEAINSVFGEVKNGPQLLLENVAGAGSSIGSNFTELRDIINKVDDYARIGVCLDTCHAFAAGYDLRYEDGLEELLNDFDKIIGLDLLKVIHLNDSKYGLASNKDEHAHIGEGEIGEKGISNIINHPLLKDKPFILETPKFSGRDKDVELVNLLRRD
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: GYRB_SPICI
Sequence: MGDNYNSESIQILEGLEAIRKRPGMYIGATNARGLHHLVWEIVDNSIDEVLANFANKIKIILNKDESITVIDNGRGIPIEIHPKTKVSTLETVFTILHAGGKFDSNTYKISGGLHGVGASVVNALSKYLKVEVRKNNKKYVMEFHNGGQILTPIKEVGSTSETGTTVTFLPDEKIFKETTIFSFSTIQNRIKQLVFLNKGLEISLVDLREEDEEKTVLYQFNNGIKDYVLELNKTIGTPLNDVFYVEGIEDNIVVEFGLQYNDNYSENIFSFCNNINTHEGGTHEEGARLAIVREINNYFKNQINKNNKGNEDKFTWDDIKEGMTIIISIRHPEPQYEGQTNQKLLNSEVKKIVSNIVGKGLSSYLLENPEDAKKIIEKISLSLKATIVAQRAKEITRRKIVMDSFSLPGKLSDCETKDAKIAELYIVEGDSAGGSAKSGRNRKFQAILPLRGKILNVEKAKQIKIFENNEINSIITALGAGIKDNFNDKKLRYQKVIIMTDADVDGAHIRILLLTFFYRYMKDLIENGNIYIAQPPLYKVENSNQIRYVYSDNELELYKEELLKQNKNYTIQRYKGLGEMNPEQLWETTMDPERRLLLKVSVNNAFEANLICNELMGENVEPRKKFIRENAKYVKNLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_HALMA
Sequence: MEYDDMLDRAMEETPEIDGTSERFEVPDPDIRQEGNVTVYENFQSTCSRLGREDDHVMKFLQNDLGTSGHIDESGRVRLTGEFDATRIEASIDEYVDEFVLCSECGLPDTQLEREQGALLLRCEACGARSATSE
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: RECO_STAAB
Sequence: MLMRQKGIIIKAVDYGESDKIITILNEHGAKVPLMARRAKKVKTGLQAQTQLFVYGLFIYNQWRGMGTLNSVDVISQHYKLQMDLYVSSYASLAAETIERSMDEGDIAPYNYQLLQFVLEKIESGTSAQLMSVVVMLKCMKRFGFTASFNRCAVSGNDTQADLIGYSFKFDGAISRQEASKDVHAVILSNKTLYLLDVLQKLPIDKMNSLNIHQEIIDEMSEIILMLYREYAGMFFKSQKLINQLKRLEQ
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: GSA1_BACCN
Sequence: MIVNFTKSEALHKEALEHIVGGVNSPSRSFKAVGGGSPVAMERGKGAYFWDVDGNKYIDYLAAYGPIITGHAHPHVTKAIKTAAENGVLYGTPTALEVKFAKMLKEAMPALDKVRFVNSGTEAVMTTIRVARAYTGRTKIMKFAGCYHGHSDLVLVAAGSGPSTLGTPDSAGVPQSIAEEVITVPFNNVETLKEALDKWGHEVAAILVEPIVGNFGIVEPKPGFLEQVNELAHAAGALVIYDEVITAFRFMYGGAQDLLGVTPDLTALGKIIGGGLPIGAYGGKKEIMEQVAPLGPAYQAGTMAGNPASMSAGIACLEVLKQEGVYEKLDKLGAMLEKGILEQAQKHNINITVNRLKGALTVYFTTNTIEDYDGAQNTDGEMFGKFFKLMLKEGINLAPSKYEAWFLTTEHTAEDIEYTIEAVGRAFAALAK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEPA_YERPE
Sequence: MKNWIVGMVALVTMVPVMAATPWQKITHPVAGSPQSIGGFANGCVIGAQPLPLESADYQVMRSDQRRYFGHPDLLNFIHRLSAQTHQQQLGTVLIGDMAMPAGGRFSSGHASHQSGLDVDIWLQLPKQRWSQQQLLKPQPIDLVAVDGKRVIPALWQPQIESLIKLAAKDNDVTRIFVNPAIKKQLCLDAGADRQWLHKVRPWFAHRAHMHVRLRCPANSLECVDQDTPPPGDGCGAELESWFQPPPPSAKPGKTLPPPLPPSCQALLDNHFATE
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NIFW_BURVG
Sequence: MTPLAERLKHLSSAEDFLQFFGVPFDQKVVDVCRLHILKRFFQYIRQQASIPQDTEAALFATYRDQLARAYRDFVASTPAEEKVFKVFQDVDGRQHVSVDTLRASLPARGTA
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.