PharMolix/UniProtQA huggingface dataset:
Protein: Y1278_MYCTU
Sequence: MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEYKDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTVLAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCDALSRALDLAAGDDAALSGTESLLIERIEAEYARYFTPTGRPTGEWSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQLRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTEIDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRAESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELLSRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWSVTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVADLAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQPAELDLVSTDTATARAELDAVEAARIAAEKDCETRRQIAAGAARRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEADLRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRALHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSVMARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDRTVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLAKMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ
What are the official names of this protein?
Uncharacterized protein Rv1278.
Protein: RL18_COXB1
Sequence: MDKQEKRIRRARRTRAKIKELGAVRLCVHRSLNHIYAQLISPRDSKVLVCASTLEKEVRSQIKHGGNIQAATAIGKLIAQRAKKAGVTKVAFDRSGYKYHGRVRALAEAVREGGIEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CYSG2_CROS8
Sequence: MDHLPIFCQLRHRACLLVGGGDVAERKARLLLEAGAALTVNALAFAPQFKAWAKQGMLRLVQGEFNASLLDDCWLAIAATDDDAVNNQVSEAAEARRIFCNVVDAPKQASFIMPSIIDRSPLMVAISSGGTSPVLARLLREKLEALLPQHLGKVAGYAGQLRRRVKQTFTSMSERRRFWEKFFVNDRLAQSLANDDEQAVTRITETLLSEPLDDRGEVVLVGAGPGDPGLLTLKGLQQIQQADIVVYDRLVSDEIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQRGKRVVRLKGGDPFIFGRGGEELETLCDAGIPFSVVPGITAASGCSAYAGLPLTHRDYAQSVRLITGHLKNGGEFDWHNLAAEKQTLVFYMGLNQAAAIQEKLIEHGMDPQMPVALVENGTSVKQRVVAGVLTELGALAQRVESPSLIIVGRVVALRDKLNWFSSK
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: HSCA_BURCM
Sequence: MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRNSVPEVLPDEAGRALLPSVVRYLEKGGRRIGHEAKEQAATDPRNTIVSVKRFMGRGKAEVEGAANAPYEFIDAPGMVQIRTIDGVKSPVEVSAEILATLRYRAEDTLGDELVGAVITVPAYFDEAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNAAEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDFDHLLFGHVLAQAGIDAKALAPEDVRLLLDRVRVLKEALSSAPQASLDVTLSNGTRLVQTISHDTFASLVEPLVQRTLTPTRKALRDAQVTPADIKGVVLVGGATRMPVIRDAVAKYFGQPPLVNLDPDQVVALGAAIQADLLAGNRGGGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPIARAQEFTTFKDGQTAMAIHVVQGERELVADCRSLARFELRGIPPMTAGAARIRVTYQVDADGLLSVFAREQHSGVEASVVVKPSYGLADDDIAKMLEDSFKTAEIDMRARALREAQVEAQRMIEATQAALAADGELLDDAERTQVDALVAALRTIAQGDDADAIETATKALADGTDEFAARRMDKSIKRALSGRRLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: VF193_IIV3
Sequence: MEESILRMHDKTTLKNMAFNRGLSRRGHNGRNASRMRKQDFIDFIMVQNHRDQSAVLGSDFLGDDMIRIFQEFIMDETFTFNPFIHLMGTIKNSTSKSPVSNQPSPEEDEPIPDLTLKPLEPCTKCECTTCMKNSIKQEENLKVHQNILNLESKIMCVVCQANVRNVVFVPCNHLATCISCSANPLMPKKCPMCRKGCKTTIKIFF
What is the function of this protein?
Plays a role early in infection by preventing host cell apoptosis.
What are the official names of this protein?
Putative apoptosis inhibitor 021L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 193R family.
Protein: ETFA_ORYSI
Sequence: MAAMVVGALRRGTATAGGSSRSFARSLPRPVSTLVVAEHEGGFVKPSSLSALAAAEAIGKDDNRVSLLLGGSGPGLHKAAEHAASSHPLVSEVLVADSDVFAHPLAEPWAELLRSVQHKGGYSHVIASSTSFGKNLLPRAAALLDVSPVTDVTSISEPRVFVRPIYAGNALCTVRYTGEDPCMMSIRSTSFSPTEAMSEAKVAPITQVDLSFLSEGSSGKSAWVNLKSQDTERPDLANAPVVVTGGRGLKSAENFKVLEQLAEKLGAAVGATRAAVDAGFVPNELQVGQTGKIVAPELYMAFGVSGAIQHLAGMRDSKVIVAVNKDADAPIFQVADYGIVADLFEVLDELLKKLPDKK
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RNH2_PSEA8
Sequence: MQLGLDFNLVEDLVAGVDEVGRGPLCGPVVTAAVILDPSRPILGLNDSKKLSEARREALFEEIREKALAWCIARAEVEEIDRLNILHATMLAMQRAVEGLSVTPRLALIDGNRCPKLAVPCAPVVKGDSQVPAIAAASILAKVSRDREMVELDRVYPGYGMAGHKGYPTAVHLEALSRLGPTPIHRRSFAPVRELLDVSVQ
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU_ARCFU
Sequence: MRATWKGSISFGLVNIPVKVYKATTQKEIQFHLLHSADGGRIRYRKVCEKCGKEVSDGEIVKGYEISKNEYVILTDEDFEKIPLKSTKSIEIRQFFDPAELGLIYYSSFYYISPDKGGEKAYYLLKKAMEETNSMGIGKMTMRGKENLVALRPYDGGIVLAQLHYIDEVRSPLELPGWGAVAEITEEELELAKKLILAMKKPLKLEEFRDEYKEALMQLIEAKLSGREIVVSEGVEEVKSLIDALKASLEAVK
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: REPB_ACIFR
Sequence: MKSEQLKQFERYAEAVGAERYRVTSIKMQADGRKQTFILDKKDGITRGFTPQEIEQRTPEMQRLQRRGENLYYTPLSDKKHHILIDDMNREKLERLIKDGYQPAAVLESSPGNYQAIITVSKLGTAHDKDVGNRLSDALNREYGDPKLSGAIHPHRAPGYENRKPKHQREDGSYPEVRLLKAERRECVKALALSSQIDAEYQRQAALKAQQPERTKAKPALELAAASGSAIDAYQRHYRDVLKRQRGGEVDLSRVDSMIAVRMRVTGHDQAAIEGAIRQCAPATRQKDEGRDWNDYAQRTARYAYSAAQPQAADLGKYRQQWEKLEGREPVRQQEQAKAQKIERDNSPGMSL
What is the function of this protein?
Functions as a primase with respect to replication at the (vegetative) origin of replication of pTF-FC2.
What are the official names of this protein?
DNA primase, Replication primase.
Protein: MSRB_THEVB
Sequence: MTKVVKTDAEWQAQLTPEQYYVTRKKGTERAFTGCYWNNKKPGLYSCVCCGTPLFRSETKYDSGTGWPSFWQPLDPNNIRMERDLSHGMVRTEVLCAVCDAHLGHVFEDGPPPTGLRYCINSAALAFVPESAASS
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: EFP_SYNE7
Sequence: MISSNDFRTGTTIEIDGAVWRVVEFLHVKPGKGSAFVRTKLKNAKTGNVVEKTFRAGETVPQAVLEKSTLQYTYKDGDDFVFMDMETYEEGRLTAATIGDRVKYLKEGMEANVITWNGQVIEVELPNSVVLEVIETDPGVKGDTATGGTKPAKVETGAQVMVPLFISVGERIKIDTRNDSYLGRE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPOB_PHOLL
Sequence: MRRILFVALSVMFLAGCPSLPPEQPEPPTPVVPVTPSEKPTPPSEKVPEPPKMSAIDWESTVQPLVEQLVKAHGLENAKLLLVDTVKNNTNGALQTMQATDALRQAISSEHVFELIPQNQVQNARQSLGLSEEDSLGLRSKAIGLARYLNAEYVLYSIVSGNSDKRDIVMQLMLVKTGEILWSGHGDVK
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
What are the official names of this protein?
Penicillin-binding protein activator LpoB, PBP activator LpoB.
What is the protein family that this protein belongs to?
Belongs to the LpoB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: CLPS_HELHP
Sequence: MAHTAFETSLDTLLEEPKMYRVLLLNDDWTAMDFVARILMEVFDKTSDEATAITLKIHNDGKGVCGIYTYDIAELKMQIVSQMAKQHGYPLRVITEEMP
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: GUAA_VIBC3
Sequence: MTKNIHDQRILILDFGSQYTQLVARRVREIGVYCELWSWDVEEADIREFNPDGIILSGGPESVTEANSPRAPQYVFDSGVPVFGVCYGMQTMAEQLGGRVATSDEREFGYAQVKISGESALFKDLDLTQDVWMSHGDKVVEIPADFVKIGETDTCPYAAMANEEKKYYGVQFHPEVTHTKNGLQMLENFVLGVCGCERLWTSESIIEDAVARIKEQVGNDEVILGLSGGVDSSVVAMLVHRAIGSKLTCVFVDNGLLRLNEGEQVMEMFGDKFGLNIIKVDAEERFLKALEGIDEPEAKRKTIGRVFVEVFDEESKKLSNAKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMKMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHAADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYEFLGKVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: TY13_BOMVA
Sequence: GKPFYPPPIYPEDM
What is the function of this protein?
Stimulates insulin release.
What are the official names of this protein?
Tryptophyllin-13.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIN9_HUMAN
Sequence: MAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRNTSSAVEMPFRNSKRSRLFSDEDDRQINTRSPKRNQRVAMVPQKFTATMSTPDKKASQKIGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVADVSQFKDLPDEIPLPLVIGTKVTARLRGVHDGLFTGQIDAVDTLNATYRVTFDRTGLGTHTIPDYEVLSNEPHETMPIAAFGQKQRPSRFFMTPPRLHYTPPLQSPIIDNDPLLGQSPWRSKISGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLISRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNISCFQNNVEIHVAHIQSGLSQMGNLHAFAANNTNRD
What is the function of this protein?
Acts as a tumor suppressor.  Inhibits DNA synthesis.  Its ability to inhibit oncogenic transformation is mediated through its association with RB1.  Plays a role in the expression of genes required for the G1/S transition.
What are the official names of this protein?
Protein lin-9 homolog, HuLin-9, hLin-9, Beta subunit-associated regulator of apoptosis, TUDOR gene similar protein, Type I interferon receptor beta chain-associated protein, pRB-associated protein.
What is the protein family that this protein belongs to?
Belongs to the lin-9 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Found in perinucleolar structures. Associated with chromatin.
Protein: CP136_MYCTU
Sequence: MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR
What are the official names of this protein?
Putative cytochrome P450 136.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: NUOK_SYNC1
Sequence: MIVPLGQVLMLAGLLFVAGLVGVLLRRNLIMILIGVEIMLNAVGLVLVGASAYWRHPDGQLVALLLMAVAAAEVTIALALVVYLKRSRGTIDINRFDGMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLPB_SALA4
Sequence: MKFDTVIMGGGLAGLLCGLQLQQHGLRCAIVTRGQSALHFSSGSLDLLSTLPDGQPVTDITAGLDALCRQAPEHPYSRLGAQKVLTLAQQAQTLLNASGAQLYGDVQQAHQRVTPLGTLRSTWLSSPEVPVWPLSAQRICVVGVSGLLDFQAHLAAASLRQRDLNVETAEIDLPELDVLRDNPTEFRAVNIARLLDNEEKWPLLYDALSPIATNCDMIIMPACFGLANDTLWRWLNERLPCALTLLPTLPPSVLGIRLHNQLQRQFVRQGGIWMPGDEVKKVTCRRGTVSEIWTRNHADIPLRPRFAVLASGSFFSSGLVAEREGIREPILGLDVQQTATRAEWYQQHFFDPQPWQQFGVVTDDAFRPSLAGNTVENLYAIGSVLAGFDPIAEGCGGGVCAVSALQAAHHIAERAGEQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: RL5_METM5
Sequence: MSFQEVWEKEPMKKPRIQKITVNFGVGEAGDRLTIGAKVIEELTGQSPVRTLAKQTNPAYGIRKKLPIGLKVTLRGKNAEEFLKNAFTAFKACGKVLYASSFDQVGNFSFGVPEHIDFPGQKYDPSVGIYGMDVCVTFDKAGYRVKSRKLKRSHIPKKHLVTKDEAIEYIQTKFDTEVVRE
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RS17_MACCJ
Sequence: MSERNNRKVYTGKVVSDKMDKTITVVVETYKTHSLYGKRVKYSKKYKAHDENNTAKMGDIVKIMETRPLSATKRFRLVEVVEESVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: MATK_FAGTA
Sequence: MEEFQGYLELYRSWQDNFLYPLILQESIYALVHNQDLGLNGSILLSKKKGYDTKYSLLVVKRLVIRMYQQNFVILSLNDSNKNEFFVPNKNLYSQRISEGFAVLAEIPFSMRVMSSLKGKERKQYQNLRSIHSIFPFLEDKFSRLNHVLDILIPHPVHTKILVQTIRYCVKDISCLHLLQLLLYEYCNNGITLKGSVSNLSKNKNQRFLLFLYNSYVCECESIFVFLRNQSSHLRSTSYGAFLARVYFYLKLEHFLKVFTKHFRVILQFFKDPFMHYVRYQGKWILASRGTFLLMTKLKYYFVNFWQCNFYLWLQTRRIYINKSLNQPIDFIGFLLSVRLNPSVVRSQMLENSFLIYNGIKKFETLVPTMSLIGSLAKAKFCNVLGHPISKPAWADLSDSDIIRRFGRMCRNLSHYYSGSSKKGGLYRIKYILRLSCARTLARKHKSTVRAFMKRLGSEFFEEFFFKEEKVISLILSRDSSISRRLYRGPIWYFDIFCIHDLASHND
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURQ_ECOHS
Sequence: MQFEKMITEGSNTASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNINLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGISCNPGSAVSTTAEFAITPIVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVNIVKNATGCSAEQAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: HLDD_BURCH
Sequence: MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDTCLAQGTQFLYASSAAIYGGSTRFVEERDVEAPLNVYGYSKFLFDQVIRRVLPSAKSQIAGFRYFNVYGPRETHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVTKVNLFFFDHPEKSGIFNLGTGRAQPFNDIASTVVNTLRALDNQAPLTLAQQVEQGLIEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVDRYVRWLSGQV
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: VG01_EHV1B
Sequence: MRPEGVSRGRASSVSISMCPPPPNGARRASLGCAPPLNSRPVCCAPSSVSLSSSSSRRSMPSLGSSRSSSLPSTGSLRSITRDPERLPSRPPSYTAINPECLLERGAERPRAWTASVMTAPPSYSEALCQAPPAYELVPELSYHPTQDPRGVYSSRSDPHQTSRRRQNPICIFIIVVATMLLILGLLLTITLSSLTNGKKEK
What are the official names of this protein?
Uncharacterized gene 1 protein.
Protein: FSR5_GIBF5
Sequence: MASLGKYVSKLAGSRVLVIGGSSGIGFGVAEAAIQNGASSVFISSSSQTKISSAIERLKENNQSAKAQLHGFPCNLGSPDTLTSEVENLFAEVAKSGKLDHVVFTAGDKLAVGKLEDFTLDAIRQAGTVRFFAPLVVAQQLRKHLDESGSSSFTVATGGATEHVSKDWSIMYSYLSGLRGMIRGLAVDLAPIRVNAVAQGPTDTEIWSYVKEMGYWDNVTGHLKGRMTTGEIGKVEDVVEAYLYLMKNKNTSGSVVETTGGTLLS
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of fusarubins, highly pigmented naphthoquinones responsible for the coloration of the fruiting bodies (PubMed:22492438, PubMed:23825955).  The non-reducing polyketide synthase FSR1 is responsible for the condensation of seven acetyl-CoA units to yield a haptaketide (PubMed:22492438).  After rings A and B are formed by aldol-type cyclization, the PKS-derived product is released as 6-O-demethylfusarubinaldehyde (PubMed:22492438).  Then, two hydroxyl groups at C-5 and C-10 are incorporated by FSR3, and simultaneously hydroxyl groups at C-6 and C-8 are methylated by FSR2 (PubMed:22492438).  The aldehyde is, on the one hand, reduced by FSR3 to 8-O-methylfusarubin alcohol, which equilibrates mainly with 8-O-methylfusarubin and only small amounts of 8-O-methylnectriafurone (PubMed:22492438).  On the other hand, the aldehyde can be oxidized to form 8-O-methylfusarubinic acid, a reaction driven by FSR3 equilibrating with 8-O-methylfusarubinlactone, finally resulting in 8-O-methylanhydrofusarubinlactol after a further reduction step and loss of water (PubMed:22492438).  8-O-Methylfusarubinic acid can also undergo decarboxylation, resulting in 8-O-methyl-13-hydroxynorjavanicin after another hydroxylation step at C-13 (PubMed:22492438).  Both steps are most likely also accomplished by FSR3 (PubMed:22492438).  No enzymatic function has been determined so far for either FSR4 and FSR5 (PubMed:22492438).  Their deletion does not alter the product spectrum, but the possibility that they catalyze specific enzymatic steps during perithecium development cannot be ruled out (PubMed:22492438).  FSR4 might possess a regulatory function in the biosynthesis of fusarubins (PubMed:22492438).
What are the official names of this protein?
Short-chain dehydrogenase/reductase fsr5, Fusarubin biosynthesis cluster protein 35.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TRPA_MYCBT
Sequence: MVAVEQSEASRLGPVFDSCRANNRAALIGYLPTGYPDVPASVAAMTALVESGCDIIEVGVPYSDPGMDGPTIARATEAALRGGVRVRDTLAAVEAISIAGGRAVVMTYWNPVLRYGVDAFARDLAAAGGLGLITPDLIPDEAQQWLAASEEHRLDRIFLVAPSSTPERLAATVEASRGFVYAASTMGVTGARDAVSQAAPELVGRVKAVSDIPVGVGLGVRSRAQAAQIAQYADGVIVGSALVTALTEGLPRLRALTGELAAGVRLGMSA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: LEU3_STAEQ
Sequence: MSYKIVALPGDGIGPEILSGTLELLKLISEKYHFEYHLESHHFGGVSIDYYGTPLTNETLQSCKNADAILLGAIGGPKWTDPNNRPEHGLLKLRKSLNLFANIRPTFVTKGASHLSPLKQDIVEGTDLVIVRELTSGIYFGEPSYVKKTEALDSLKYSSQEIERIVRIAFNLANRRRKKLTSVDKENVLSSSKLWRQIVNDVKKDYPEVEVNHMLVDACSMHLITQPTQFDVIVTENLFGDILSDEASVIPGSLGLSPSASFGQTGTRLYEPIHGSAPDIANEDKANPFGMVLSLALCLRESLNQNDAANELESIVYSFIQSNKTTADLGGQYRTSEIFKLLKEKYL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOM06_DROME
Sequence: MKLLSITFLFGLLALASANPLSPGNVIINGDCKVCNIRGD
What is the function of this protein?
Secreted immune-induced peptide induced by Toll signaling.  Has a role in resistance to bacterial and fungal infections (PubMed:25915418, PubMed:29920489).  The strength of antimicrobial activity appears to correlate with the overall level of expression (PubMed:29920489).
What are the official names of this protein?
Bomanin Short 6, Bomanin-068.
What is the protein family that this protein belongs to?
Belongs to the bomanin family.
Protein: ISK11_MOUSE
Sequence: MSSTWIKFLFILTLVLLPYFVAESAVASPESLRKVPNCTLYKSESDCSRTLIPVCADNQMTYYNACYFCLEQLVSPIKYKYHGICTKE
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 11.
What are the subcellular locations of this protein?
Secreted.
Protein: Y539_MYCTU
Sequence: MAGDAVTVVLPCLNEEESLPAVLAAIPAGYRALVVDNNSTDDTATVAARHGAQVVVEPRPGYGSAVHAGVLAATTPIVAVIDADGSMDAGDLPKLVAELDKGADLVTGRRRPVAGLHWPWVARVGTVVMSWRLRTRHRLPVHDIAPMRVARREALLDLGVVDRRSGYPLELLVRAAAAGWRVVELDVSYGPRTGGKSKVSGSLRGSIIAILDFWKVIS
What are the official names of this protein?
Uncharacterized glycosyltransferase Rv0539.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.