PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_CANTT
Sequence: MISRTPLFRTSIPIQRTLATNVKPRRKRTVFTDELNKGPSFEDFVSGKAKDMMEDPLELARKDPNAKLPKWLKVPIPKGKSFHNVKKDVRELKLSTVCEEAKCPNISECWGGKKSEATATIMLLGDTCTRGCRFCSVKTNRKPAAPDPNEPENTAEAIKRWGLGYVVLTTVDRDDLVDGGARHLAETVEKIKQKAPQILVEVLGGDFRGDLDMVEILANSGLDVYAHNLETVEDLTPHIRDRRATYRQSLAVLERAKKTKPSLVTKTSLMLGFGETDEQIMKTLKDLREIGCDVVTFGQYMRPTKRHMKVVEYVTPEKFDYWRDTALDMGFLYVASGPLVRSSYKAGEAFIENVLKKRRHNVGETPRLQSVAKPSVY
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYFB_RHILO
Sequence: MKFTLSWLKDHLETDASLDEIVERLTSIGLEVEHVDDKSSLKPFVIAKVLTAVQHPDADRLRVLTVDTGDGKSPVQVVCGAPNARAGLIGAFAAPGTYVPGIDVTLTVGKIRGVESHGMMCSERELELSDEHNGIIDLPADAPVGTSFASYAHLDDPVIEINLTPNRPDATSVYGIARDLAASGLGTLKSAAVEKIPGKGETPVKVVIEAPELCPGFALRLVRGVKNGPSPKWLQQRLIAIGLRPISALVDITNYVTFDRGRPLHVFDARKVAGNLVVRRAHDGEKVMALDGREYTLTPDMCAIADDNGVESIAGVMGGEHSGCDENTTDVLIESALWDPITTARTGRTLGIITDARYRFERGVDPEFMVPGVELATRLVLDLCGGEPAETEVVGYAGHKPKIVSFPISEVTRLTGIEVPKEESLDILSRLGFKPQGSSEVVDVALPSWRPDVDGKADLVEEVMRIHGVDNIAPQPLGAHDAVNSKILTTLQVRTRTAKRALAVRGMMEAVTWSFIPAKHAELFGGGQTALKLANPIAADMSDMRPSLLPGLIAAAQRNADKGIGDVALFEVSGTYEGDGADQQRRVAAGVRRGTAKLDGSGRSWAGNSGPVGVFDAKADAIAALEACGAPVERLQIEAGGPAWYHPGRSGTIKLGPKTVLGTFGEFHPKTMEGLDVSGPLCGFEVFVDAVPEPKAKPTKTKPKLELSAFQAVKRDFAFVVDKAVEAGTLVRAALAADKKLITAVSVFDIFEGASLGADKKSIAIEVSIQPVEKTLTDEDFEALAKRVVENVGKQTGGVLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBD4_SCHPO
Sequence: MDSFHPTPGKPTTATSNSSLNFFVRNREKSIRCSSLHQTFTAPSPEASPSIGLRYVNYSMSDETDESMFPLDSELTDMEDDDTEYISDSTTDLPSAAMARGTRQLSYNENLDQRSFSKTPNKHIEVKNLKDLCSPSHSGRISKSLCPVLRRKSLLPKPKMFQRVASALYEESSPLELEIRSESEFSKMFFEPKKSSSFVSRAASPAMVGPGVPFYSSITGANGNVLAPSGSLKAVENSDVIESSAEDSSNTDNPSTKPSNEMPISPLLSSSVFFKDTEMSTPNSNHSRSRTPSSKKRTRWGEEIIDLSKRRAVSPSIYYDLDKKCSPIHSVMVSPLKIKDTHEVLMNLKL
What are the official names of this protein?
Uncharacterized protein C16C6.04.
Protein: FEN1_BRAFL
Sequence: MGIQGLAKLIGDHAPGAMKENEIKNYFGRKVAIDASMSIYQFLIAVRQDGNMLTNDAGEATSHLMGMFYRTIRMVDNGIKPVYVFDGKPPNMKSGELAKRAERREEAQKALEKAEEAGEAEDVNKFQKRLVKVTKEHNAECKKLLTLMGIPYVDAPCEAEAQCAELAKKGKVYAAGTEDMDVLTFGTNIMLRHLTFSEARKMPIKEYYYDRLLAELDLTQDQFIDLCILLGCDYCDSIRGIGPKRAIELIRQYKSIEEILKHIDTKKFPVPEDWPYDQARKLFKEPEVTPADQVELKWVDPDEEGLVQYMSNEKGFSEDRIKNGAKKLKNARHTSTQGRLDSFFKVMSSPSVKRKEPPKGAKGSASKKAKMSGGKFKKPK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: Y866_METKA
Sequence: MTDREEVVELRGHIIDSLIFSRVLDTIMEMGGDFEILEFKVGKRKTDPSFAKILVKGKDPEHLREIVSELRKYGAVPVHTQEVRLEPAPADGVCPRGFYTTTNHRTFVLFDGEWIEVEDIEMDCAIVVYPEERRAVAKPIREVREGELVVVGDRGVRVKPPERPRGRTGIFGFMESEVSPEKPTPTLIRRIAEELEWHRKNGKIVVVVGPAVIHAGARDDLAWMIREGYVDVLFAGNAVATHDVEASLFGTSLGVDLETGEPVKGGHSHHLYAINEIRRVGGLREAVEKGILKDGIMYECIVNDVPYVLAGSIRDDGPIPDVITDVMEAQAEMRRHLKGATLVLMMATMLHSIATGNLLPSWVKTICVDINPAVVTKLMDRGTAQALGIVSDVGVFLPELVKELKRVRDDEA
What are the official names of this protein?
Uncharacterized protein MK0866.
Protein: ENO_YERPE
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNGPIAQAVIGKDAKDQANIDKIMIDLDGTENKSQFGANAILAVSLAAAKAAAASKGMPLYEHIAELNGTPGKFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRIGSEVFHHLAKVLKAKGLNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEDLTKQYPIVSIEDGLDESDWAGFKYQTEVLGDKIQLVGDDLFVTNTKILKEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGDRAPFNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: METK_LIMRD
Sequence: MAERHLFTSESVSEGHPDKIADQISDAILDELLKKDPDSRVAVETSVTTGLVLVFGEVSTKAYVNIQQIVRDTIRKIGYTDGKYGFDADNCAVITAIDEQSPDIAQGVDDSLETREGEADPLDKIGAGDQGLMFGYATDETPEYMPLTLVLSHKLMRKIAQLRKDGVISYLRPDAKAEVTVEYDENDKPLRVDTVVLSTQHDPEVSLDQIKKDIKEQVIEAVIPAEYLDDQTKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGAAHHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGYAKKAEIQVAYAIGVAEPVSIMINTYGTGTRSEEELIAAVRKAFDLRPAGIIEMLDLKRPIYKQTAAYGHFGRTDVDLPWEHLDKVDELKEILG
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_XYLF2
Sequence: MSKFFRRRKFCKFTAEGIKEIDYKDLNTLRQYLTENGRIVPSRVTGTKSKYQRQLTTAVKLARFLALIPYTDNHDI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: UVRA_MYCTU
Sequence: MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVDHELGAPHREQRFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESKGEHGAKSIAEVCELSIADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLVRVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVIKTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVGGGASAATSRSNRRRNVSA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.  Alone it slightly inhibits RecA-mediated DNA strand exchange, in concert with UvrD1 greatly inhibits RecA-mediated DNA strand exchange.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDCC_SALNS
Sequence: MSTTDSIVSSQAKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLQMPALNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLSNIELTGHDGILVTVWLGISIMVFSFNFSPIVSSFVVSKREEHEKEFGREFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPQNMADAKAQNIPVLSYLANHFASLSGTKSTFATVLEYGASIIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKTKVSMGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTLIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMD_ACIBY
Sequence: MKQQAKSRKPQQPEYIFQVETLSHEGRGIAHYGSHPDHPADKHGKKVFIRYALPGETVKAQITHEAKRLEEAEMVELLAEPSANRVEAVCPHYGICGGCSMQHIHPDEQIHLKQNVLQSHLQHFAGIQPEQWLEPIRSLQSDYRRRARIGVRYLPKQDRLILGFREHHSNRLTSIHTCSVLDKKLSDNLPELRNLLQSLKGKAHIGHVELAKGDHEISLLVRHIEKLNNADVNQLRQFALHKGWQLYLQPKGPESLRRIDEEQGAMRLHYALNAFDVNFAFSPLDFTQVNATVNEQMVQLACELLQLQQGERVLDLFCGLGNFSLPLARCVGAKGQVVGVEASEEMVQRATDNAKRNNLVQASFFSQDLTKDFSHHSWANQGFDALLIDPPRAGAYEIMQYVPNFGAKRIVYVSCNPATLARDAGVLVQHGYQLKKAAVMDMFTHTEHVESIALFEKIQEIND
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: FB85_ARATH
Sequence: MVNTSFETLPRHMQMEILSRVPLKFLMKFMCVSKKWASIIRGEEFREDYLFQSMKRPRVLFVIDHREYLPIKPEAFFHSVYQEDQPLLLSGKQRMRTFETPLVQVFQPIRGLICQQGYGKIVICNPGLKKFRSLPQIKVHKGAPMRTFFGYDEDKDVFKVLCITWLRNGKRSEVSKEYLVYTMGSDEESSSWRLITCEHDHAPVTEGLFKGGVLYYGAKSNNGKSVVMSFNVNSEDFSVIELEVEISPYWRLVNYKGDIALMNNIEDSLYHSREFEMWVRNEVTGNWDRTSIKISHWNGTVDGKTFYFKGTIGTKELAFAPDYWFGEQHFVSYYDTETKNLRRFDIEGMVDQDDFVRTFFDHVDSTWLI
What are the official names of this protein?
Putative F-box protein At1g70960.
Protein: GCN4_YEAST
Sequence: MSEYQPSLFALNPMGFSPLDGSKSTNENVSASTSTAKPMVGQLIFDKFIKTEEDPIIKQDTPSNLDFDFALPQTATAPDAKTVLPIPELDDAVVESFFSSSTDSTPMFEYENLEDNSKEWTSLFDNDIPVTTDDVSLADKAIESTEEVSLVPSNLEVSTTSFLPTPVLEDAKLTQTRKVKKPNSVVKKSHHVGKDDESRLDHLGVVAYNRKQRSIPLSPIVPESSDPAALKRARNTEAARRSRARKLQRMKQLEDKVEELLSKNYHLENEVARLKKLVGER
What is the function of this protein?
Master transcriptional regulator that mediates the response to amino acid starvation (PubMed:11390663, PubMed:29628310).  Binds variations of the DNA sequence 5'-ATGA[CG]TCAT-3' in canonical nucleosome-depleted 5'-positioned promoters, and also within coding sequences and 3' non-coding regions (PubMed:29628310, PubMed:11390663, PubMed:1473154, PubMed:2277632, PubMed:1939099, PubMed:7664107, PubMed:2204805, PubMed:3678204, PubMed:3532321, PubMed:3530496).  During nutrient starvation (low or poor amino acid, carbon or purine sources), it activates genes required for amino acid biosynthesis and transport, autophagy, cofactor biosynthesis and transport, mitochondrial transport, and additional downstream transcription factors (PubMed:11390663, PubMed:29628310, PubMed:8336737, PubMed:1939099, PubMed:10733573, PubMed:7862116).  Activates transcription by recruiting multiple coactivators, including the mediator complex, the SAGA complex, and the SWI/SNF complex, to enable assembly of the pre-initiation complex at core promoters (PubMed:19940160, PubMed:9488488, PubMed:10549298).
What are the official names of this protein?
General control transcription factor GCN4, Amino acid biosynthesis regulatory protein, General control protein GCN4.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. GCN4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to the nucleus independently of cellular amino acid levels.
Protein: YIDK_ECOLI
Sequence: MNSLQILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGIATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHGAAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFMQGIEQLTTVHAEKLNSIGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLAEGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPMVGFFGAVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLVAPWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITINYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDMKPWKNVKIASIGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPDGKDSL
What are the official names of this protein?
Uncharacterized symporter YidK.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MINE_BURM9
Sequence: MSILSFLLGEKKKSAAVAKERLQLIIAHERVGGRPPADYLPALQKELVAVISKYVKISNDDIRVSLERQDDLEVLEVKIEIPQA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RPO1C_PYRHO
Sequence: MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKVEVETIIDEVIKEYEKALIEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEVDPERLEKSGLTMEKILKKLQSSFKSAEFEADGYTLIVRPKKIEKISDLRRLSEKVKKHRLKGLSGVGKTIIRKEGDEYVIYTEGSNFKQVLKVPGVDPTRTRTNNIHEIAEVLGIEAARNAIIEEIINTMHEQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTMKLPLKPQKEKEEV
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLHDB_DROVI
Sequence: MGDPLLPGSTGLGSGPAAAATGGSGTTGTGLGSGGTSGAERPPSPARLTHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLSGHLYAIGGSDGQCPLNTVERYDPRQNKWVAVNPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMWCDNSFLLHDR
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  May have a role in synapse differentiation and growth (By similarity).
What are the official names of this protein?
Kelch-like protein diablo.
Protein: KAD_ECOLU
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_GEOSW
Sequence: MLMPKRVKYRREHRGRMKGRAKGGTEVHFGEYGLQALESAWITNRQIEAARRAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKVMFEVGGVSEEVAREALRLASHKLPIKCKFVKREEIGGEANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ATPL_ECOBW
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRS2_CANAL
Sequence: MYHIHRLLAPIRSNSVFFSLAQLPKPSLIGCRYKSNNVGSQDSKRTSKNSILHNLGSYSNSAESEILNKLKPITPNDLYVSCTSFDRIGNITAVSRKYPKMQFLKENHLFPRDLRKIDTSSIDVVPVIMIRPSSAILVNLLHIKAIIKKDNVMVFDTSKSEVATKLGIFMYDLELKLKSPANNVCYEFRALESILVSVTSYLEAEIKLHRQQCGIILAELEDEVDRAKLQELLIRSKKLSSFHQRAILIRDVLEELLENDEDLAGMYLTDLKRFEPEEENYEEIESILESYYNQCDEYVQQAGSLLSDIKATEEIVNIILDANRNSLMLFELKITVYTLGFTVATLVPAFYGMNLKNYIEETNWGFGLVLVVSLLQGLAITWLNFRKLHKVQKLTMMGTSNSSKAGTGLSRHIPPTSRVDRWKRGSFLYRLFYGSGGKYSKPSKKFDRPTNREKDAMWRMINDDKAMK
What is the function of this protein?
High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix.  Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.  It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes.
What are the official names of this protein?
Mitochondrial inner membrane magnesium transporter MRS2, RNA-splicing protein MRS2.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HEMH_LEPBA
Sequence: MITNKVKTLILVNLGGPRTPSEIEVFLRDLFSDPFVFDLPLPEFLRLRLARFIAKKRAPKVQKSYESMGFGGGSPLVEETAKQAHALELALNERSSEQWNVKVAMACGYPNMRDIEFGKPNQDTVYLPLYPQFSRSTVLSTLAILETKFGECPVGSGGYVPHFGLDPNFHSISAKFIYEFFTNQLPKDQYLHYPEEKPNCDWRNLDLVFSAHGVPMRLIHKGDRYMEEVELSVKGIADELSKFGFNGGVHISYQSKVGPAKWTEPSTIQMISSLAKQGKHIAVYPISFVSDHLETLEEIGEQFKDLTWEMGGKSFVRIPALGIYPSFIQFLAEKVMHSDRKIQHCICREKGGESLQHCRFKD
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S39A9_DANRE
Sequence: MDDFSSISLLSLSMLIGCYVAGTIPLAVNFSEEKLKLVTVLGAGLLCGTALAVIIPEGVHALYEEMLEGVHNHGHGQVEAEVSEQKVAEGVVRPSGEHGHGHEQLHAYIGISLVLGFVFMLLVDQIGSAHMHSSDDPEAARAASSKITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVLAMVTYVGLSQSSKEALSDVNATGVAMLFSAGTFLYVATVHVLPEVGGMGGHSHSPGGSAGKGLSKLEVGALVLGCLIPLVLSIGHQH
What is the function of this protein?
Has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through G protein activation and are required for the androgen-dependent apoptotic response.  Upon androgen binding, mediates apoptosis by directly activating a stimulatory G protein that leads to increased cAMP levels and MAP kinase activity and which is accompanied by increased intracellular free zinc levels (By similarity).  May play a role in the proper zinc modulation during egg activation (PubMed:32973303).
What are the official names of this protein?
Zinc transporter ZIP9, Solute carrier family 39 member 9, Zrt- and Irt-like protein 9, ZIP-9.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS5_PARD8
Sequence: MANNRVKSTNDLELKDRLVAINRVTKVTKGGRTFSFAAIVVVGNEDGIVGWGLGKAGEVTTAIAKGVEAAKKNLIKVPVHKGTIPHEQLAKFGGAQVLIRPASHGTGVKAGGAMRAVLESVGITDVLAKSKGSSNPHNLVKATIAALGELRSPFDVAQNRGVAVEKVFRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RECO_GEOMG
Sequence: MESTRTEAIVLAAMDYRESDRIVTLFTLQYGKVRGVAKGAKRSARRFGPALEPFARIGVELVVREGLSSLRGADIVTLYPGIRRDLRAIGLAGYAVELVDRYLPDGAPSPRLFRLLSSYLERLDQGEPLPSDRRFFEANFLNILGYRISLDHCASCGVELPATAERRTGASGMILCANCGRYGASVGPEAAALLGRCIATGRFGAVLFSPQSLREAGTLLDGAIAAHLTRPLNSLAFLKQIEPD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: HSL56_DICDI
Sequence: MTILSAITSISRPNKISKSVISSNGGASLSMGSNSVSCFNACGGGSSYSYSSSYSGSGLDYSYKANYSSSTGYNSSVVIASSTCHCS
What are the official names of this protein?
HssA/B-like protein 56.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.