PharMolix/UniProtQA huggingface dataset:
Protein: ISPS_POPAL
Sequence: MATELLCLHRPISLTHKLFRNPLPKVIQATPLTLKLRCSVSTENVSFTETETEARRSANYEPNSWDYDYLLSSDTDESIEVYKDKAKKLEAEVRREINNEKAEFLTLLELIDNVQRLGLGYRFESDIRGALDRFVSSGGFDAVTKTSLHGTALSFRLLRQHGFEVSQEAFSGFKDQNGNFLENLKEDIKAILSLYEASFLALEGENILDEAKVFAISHLKELSEEKIGKELAEQVNHALELPLHRRTQRLEAVWSIEAYRKKEDANQVLLELAILDYNMIQSVYQRDLRETSRWWRRVGLATKLHFARDRLIESFYWAVGVAFEPQYSDCRNSVAKMFSFVTIIDDIYDVYGTLDELELFTDAVERWDVNAINDLPDYMKLCFLALYNTINEIAYDNLKDKGENILPYLTKAWADLCNAFLQEAKWLYNKSTPTFDDYFGNAWKSSSGPLQLVFAYFAVVQNIKKEEIENLQKYHDTISRPSHIFRLCNDLASASAEIARGETANSVSCYMRTKGISEELATESVMNLIDETWKKMNKEKLGGSLFAKPFVETAINLARQSHCTYHNGDAHTSPDELTRKRVLSVITEPILPFER
What is the function of this protein?
Lyase that catalyzes the formation of isoprene from dimethylallyl diphosphate, but not from isopentenyl diphosphate or geranyl diphosphate.
What are the official names of this protein?
Isoprene synthase, chloroplastic, PaIspS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RRAA_ECOSM
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_ACTP7
Sequence: MTQNLQMADRFDSSAVEQALYKHWEEQGYFKPTENPSLPSYCIAIPPPNVTGSLHMGHAFQQTLMDTLIRFNRMEGNNTLWQTGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFINKIWDWKAYSGGTISQQMRRLGNSIDWDREHFTMDEGLSNAVKEVFVRLHEEGLIYRGKRLVNWDPKLHTAISDLEVENKESKGSLWHFRYPLANGAKTADGKDYLVVATTRPETVLGDTAVAVHPEDERYQSLIGKTVVLPLANREIPIVADEYVDREFGTGVVKITPAHDFNDYEVGKRHGLPMVNVMTMNADIRAEAEIIGTDGKPLTTYEAKIPADYQGLERFAARKKVVADFEALGLLDEIKPHDLKVPYGDRGGVPIEPMLTDQWYVSVKPLAEVATKAVEDGEIQFVPKQYENLYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVARSEEEVRQKHNLPADLALRQDEDVLDTWFSSGLWTFSTLGWPEQTKELKMFHPTDVLITGFDIIFFWVARMIMFTMHFVKDENGKPQVPFKTVYVTGLIRDEQGQKMSKSKGNVLDPIDMIDGISLEDLLEKRTGNMMQPQLAEKIAKATRKEFENGIAAHGTDALRFTLAALASNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNDKLDLSAGEVEYSLADRWIESKFNRTVGEFREALSQYRFDLAANAIYDFTWNEFCDWYLELTKPVFANGTEAQKRGASQTLVRVLEKLLRLAHPIMPFITEEIWQKVKGFAGIDADTIMLQPFPKVVKSELDESAEMQIGWIKELIIAVRNIRAESNIAPSKGLEFLVRNVSDEQRKILAENDRLLKAMAKLDSVQVLSADENAPLSVAKLVGNVEVLIPMAGFINKEAELARLTKEIEKMRGEITRIENKLGNEAFVAKAPEAVIAKEREKMQEYQNGLEKLQTQYQAIENL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HS7C4_DICDI
Sequence: MPSMGIDLGTTYSCVGVCNEKGRIEIIANDQGNRTTPSYVSFNNRECLIGDDAMNQVAMNPVNTIFDVKRLFGRKYSDSVVQSDMKLWPFKVIANKFDDKPLIQVDFKGETKTFSPEEISSMVLSKMKEIVEQHLGEPVTDAVITVPAYFNDRQRHATKYAGTISNLNVLRIINEPTATAIAYGLHRRGIDDMKVLIIDLGGGTFDVSLFNIEDGIYEILLSGGDNHLGGADFNNRLMNHFIDEFKLKHKKDITNNQRAIFRLRTACERAKRTLSISSLASIEIDSLYDGIDFYSTITRTHFEKLCSDLFHSCIDHVETILNKCKLDKSLVDEIVLAGGSTQIPKIQRMFKEYFNGKEFNNSINPDEVVAYGAAVQSGVISGKGSNFPQLIFLNVTPLSMGIETVGGIMTNLVERNTHIPIKKTQTFSTQYDNQTNVLIQIYEGERTMTKDNNLIGTFELNGIPPAPRGVTQIEVCFDVDIDGILTVSAEDKTTKKVQKITISNINDHLSKVEIEKMIVDGEKFKQQDQQQKKELIESNYKIYCGDENTLDFEITQKLLGSAQSTEMNE
What is the function of this protein?
May function in protein folding and assembly, and disassembly of protein complexes.
What are the official names of this protein?
Heat shock cognate 70 kDa protein 4, HSC70-4.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SCNNG_XENLA
Sequence: MSKSGKKLTQKLKKNLPVTGPQAPTLYELMQWYCLNTNTHGCRRIVVSKGRLRRWIWISLTLCAVAVIFWQCALLLMSYYSVSASITVTFQKLVYPAVTICNLNPYSYSKVKDRLAALEKETSQTLKNIYGFTEPLIRSKRDVGVNVENSTEDIFLKQIPLYRLESVKGSQLVVSDLKTKKRTRMSAKVIHRDAESVQDPGNMVGFKLCDPKNSSDCTIFTFSSGVNAIQEWYRLHYTNILAKISMEDKIAMGYKADELIVTCFFDGLSCDARNFTLFHHPLYGNCYTFNSAERGNLLVSSMGGAEYGLKVVLYIDEDEYNPYLSTAAGAKILVHDQDEYPFIEYLGTELETATETSIGMQLTESAKLSDPYSDCTMDGRDVSVENLYNKKYTLQICLNSCFQREMVRSCGCAHYDQPLPNGAKYCNYEEYPSWIYCYFKVYKQFVQEELGCQSACRESCSFKEWTLTRSLAKWPSLNSEEWMLRVLSWELGEKLNKNLTKNDLANLNIFYQDLNSRSISESPTYNIVTLLSNFGGQLGLWMSCSMICVLEIIEVFFIDSFWVVLRQRWRNWWENRKENQAEDTPEIPVPTMTGHDNPLCVDNPICLGEEDPPTFNSALQLPQSQDSHVPRTPPPKYNTLRIQSAFQLETIDSDEDVERL
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.
Protein: FMT_CERS1
Sequence: MRLIFMGSPDFSVPVLEALHAHHEVVCVYCQPPRPAGRGKKDRPTPVQTRAEELGLPVRYPTSLRTPEAQAEFAALGAEAAVVVAYGLILPQPILDAPERGCLNIHASLLPRWRGAAPIHRAILAGDEETGICIMQMEAGLDTGPVLMCEKTHIGPEETVQDLHDRLSDMGARLILGALGALDDLVPRPQPDAGVTYAEKIAKAEAGIDWTRPAAEIDRQIRGLSPFPGAWTLLNGERVKLLRCRLAEGQGAPGAVLPGLTIACGTGAVEITLAQREGKRPMEPEEFLRGFPLPEGSRAHTA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RPPH_ACIET
Sequence: MLDRDGFRPNVGIILLNQRNQVFWGKRIRTHSWQFPQGGIDRGETPEQAMFRELHEEVGLLPPQVRVIARTRDWLRYEVPDRFIRRDARGHYKGQKQIWYLLQLLGHDWDLNLRATNHPEFDAWRWNDYWVPLDVVVEFKRGVYEMALTELARFLPRHEQRNRYLRSGMRTREHESSGQASLARTSSLLVKPGMELPPGASFDPDPQNSVPAPLEALPTLPVPKKPLDA
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: SYP_STUS1
Sequence: MRTSQFLLSTLKETPSDAVVISHQLMLRAGMIRKLASGLYTWMPMGLRALRKAEAIVREEMNKAGALEVLMPAIQPAELWQESGRWEQYGPELLRLKDRHDREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPRFGLMRGREFLMKDAYSFHLNQESLQETYDRMHQAYCNIFTRLGLNFRPVQADTGSIGGTGSHEFHVLAESGEDDIAFSDSSDYAANIEKAEAIPRETERAAPGEELRLIDTPDAKTIIELVEQFGVAVEKTVKTLVVHGVEKGQLVALIVRGDHELNEIKAANLAQVASPLVFASEAEIRAAIGAGPGSLGPLNLPIPCVIDRSVALMSDFSAGANIDDKHYLGLNWERDLPLPQVADLRNVVAGDPSPDGKGSLVIKRGIEVGHIFQLGTKYSEAMNCQVMGENGKPATLIMGCYGIGVSRVVAAAIEQNYDERGILWPDALAPFQIALVPMKYETEAVREATDKLYAELTAAGYEVLLDDRDKKTSPGVKFADMELIGIPHRIVVSDRGLADGMLEYKHRRDAQPQQVAVSDILSFINSRVHR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
Protein: TM41B_PONAB
Sequence: MAKGRVAERSQMGADHTTPVGDGAAGTRGPAAPGSRDYQKEKSWAEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLHQPTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE
What is the function of this protein?
Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes.  Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine.  Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted by ATG2 (ATG2A or ATG2B) to mediate autophagosome assembly.  In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required (By similarity).  Required for normal motor neuron development (By similarity).
What are the official names of this protein?
Transmembrane protein 41B.
What is the protein family that this protein belongs to?
Belongs to the TMEM41 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endomembrane system. Note=Localized to specific membrane structures termed mitochondria- associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria.
Protein: PSTB2_HALSA
Sequence: MSDTPQSEPRRSDDRSGADDATAAAAGSTDAAAAAVSSKTGGIAGPPGGPGEVDGDEPAVARTVGESDEQLQDAWTDYEFDGDAKVSVSDLDTYYGEERALESVSLDIPAESVTALIGPSGCGKSTFLRCLNRMNDRIRGARVEGRVALDDRDVYGDGVNLVELRRQVGMVFQEPNPFPKSIRDNISYGPRKHGDLETGLLARLLGRDDRDAERDLVERALRRAALWDEVNDRLGDNALGLSGGQQQRLCIARCLAVDPDVILMDEPASALDPVATAKIEDLIEELAEEYTVVVVTHNMQQAARISDQTAVFLTGGRLAEYDATDAIFQNPQSQRVEDYVAGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CTAA_ROSDO
Sequence: MSSKRKLFEEVGAAAATRPAAQPGLIDKRHSGARKAIRVWLQILFALVFIMIAVGGLTRLTDSGLSITEWRPLTGALPPLSEAEWQSEFEKYQAIDEFRIQNQWMQMADFKVIYWWEWGHRQLGRVIGVVWALGFGYFLVRRQVPAGWHGKLLFLGLLGGAQGAIGWWMVASGVTQGEGVTDVASYRLATHLGLAFVILGFIAWYIMELGRSAPDLMQARRIKEGKQWGMSTGLLHFTFLQILLGALVAGIDAGRSYTDWPMMGGQWFPSTALVLEPIWRNFFESPGLVQFMHRVTGYVLILFTVVVWLRGRRSSHPHTRFAFNAVLAAMTLQIVLGIVTVLYGAPAHIAIFHQTLAVIVWVLILRARFLSGYPIATSVRGT
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRAZ_HELMI
Sequence: MFMGEYQHAIDPKGRLFMPARLRESLGEAFVATKGLDGCLFVYPKEEWKRLEEKLKALPFTRADARAFQRFFFSGAGECEVDKQGRILVPAHLREHAALEKDVVIIGAGARVEIWSRERWSKYNEKAAPSYEEVAEKLIDFDL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: VPS27_PICST
Sequence: MSWFGSSSDSTIELDNKIQEATSESIPNGELDLPLALEVTDLIRSKSLPPIQCMRSLKKRLGMTYSNPNLLSSTLKLVDLCIKNCGSHFLNEIASKEFMDYLVDFIFKVHYDTKNYQVRNSEAKMNVGELILSLIKEWSILFSNSSDLSYVTRCFERLESEAYNFPDFAETSALNSKFVDTEVPPDWVDDDKCMICYDKFSMINRKHHCRACGGVFCQTHSSNFIPLVSLGISKPVRACDNCLAKQKSKNKPSQHNSSSHSRGTSRVQEDDEDEMLRKAIELSLQDTQIPVSAPVARDAPTNSSQTKTITDEDDDEDLKAAIAASMKDYQDQERLREEQQKQWQQEQEEKHHQEEQSDFYNYSIPKPSNYSQQLPYVQSVASLTEEEEADINKFITLMYQVKNDQNISYARLHDEKLTDLHTKVCPLRSKVTKNLIYTVERQKAFTELNNKIAAITRLYEEHLDSKLKQTYGYQQSVPPVQLPEINDYMRGPQSNYEQSIPAQGTGYQQQAGYVHPETTGYPSYPGGQQPIPQQPIAQQPSGSRPSAQQAQKAPEQKHEQQQTSVPTFAYPPQESYPPEGEDDEEQSNFELPPLPNQAQNDFSYPPTQSYDSPSEPMYPNDSTDQQYNVYPPNGAGSEESKDEYSSGELQPVQPTREHVLRTRSSELPPHAVEQASARFPPIDTVEEEYQNSNNSSVPYPDVSFPIAPTQNLQPQQEPPKKFVPEPEPLIDI
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 27.
What is the protein family that this protein belongs to?
Belongs to the VPS27 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NODX_HYPPI
Sequence: MESSADNTVPKQAESVFIREILENPLMPNLPPELAEIAKFVSFEGNVKPSIPVNWRLAESISALKAFEATFLNYLAHRKYGVRPSNVSINTDHATLFLMSPMLTQIEDRGEVRPFSPFDTLTAELFPNRDKHRANASLQRALITNIYKTKDGRFYHTHGGMNPEPTLQALGLPVEGEVQDTSEVVTDRIQQRLSKYDATHLDHLLNEEHRQAGTIVYSSAEYFASEHGQKNGKVGLYEVIRDPNSSQPAAWWPDHPNAPSSPKRPLAGLKVVDLTRAIAGPTITRSLAEMGASVMRVTSPDITDMSVLHQDLNWGKWNSWLRLDVESDRQKLRDLILDADVVVDSYRPGVMKRFGFGYDEVFNLVRDRSRGIIYVRENCYGWYGPWSHRSGWQQISDACCGISTSYGHAMGLEEPVTPALFNSDYCTGICGSTAVLDALVQRAEKGGSYRVDVSINYYNQWLVRSVGTYDEHTWTDLFRRHDAPVFRHYHSMQYMLPKLLTALYKFDGEILFQREFFGPFRSGALNTTFIQVRPIARFKDDAIELKYNVGTRGNGVDAPTWPADLRREIVRDEDEQGSGFRSGSGLGSGSIAD
What is the function of this protein?
Acetyl-coenzyme A transferase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes nodulisporic acids (NA).  Nodulisporic acid A (NAA) and its chemically modified derivatives are of particular significance because of their highly potent insecticidal activity against blood-feeding arthropods and lack of observable adverse effects on mammals, in particular the tremogenicity associated with the paspaline-derived IDTs is not observed (PubMed:29283570).  The geranylgeranyl diphosphate (GGPP) synthase ggs1, localized outside of the cluster, is proposed to catalyze the first step in nodulisporic acid biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:29283570).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase nodC then forms 3-geranylgeranylindole (3-GGI) (PubMed:29283570).  Epoxidation by the FAD-dependent monooxygenase nodM leads to a single-epoxidized-GGI that is substrate of the terpene cyclase nodB for cyclization to yield emindole SB (PubMed:29283570).  The terminal methyl carbon, C28, of emindole SB is then oxidized by the cytochrome P450 monooxygenase nodW to produce nodulisporic acid F (NAF), the pentacyclic core of NAA (PubMed:29283570).  NAF is converted to nodulisporic acid E (NAE) via prenylation.  This step is probably performed by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  Several oxidation steps performed by the FAD-linked oxidoreductase nodO and one of the cytochrome P450 monooxygenase nodR, nodX or nodZ further convert NAE to nodulisporic acid D (NAD) (Probable).  NAD is substrate of cytochrome P450 monooxygenase nodJ to produce the precursor of nodulisporic acid C (NAC), converted to NAC by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  The FAD-dependent monooxygenase nodY2 then oxidizes NAC to nodulisporic acid B (NAB) (Probable).  Finally NAB is converted to NAA by one of the cytochrome P450 monooxygenases nodR, nodX or nodZ (Probable).
What are the official names of this protein?
Acetyl-coenzyme A transferase nodX, Nodulisporic acid biosynthesis cluster protein X.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: UL95_HHV6Z
Sequence: MWVMSQVRSMEPDLTLAAVYQAAANLTEQDKEIFSEAVKTAFSVCSSAAPSARLRMIETPTQNFMFVTSVIPSGVPSGEKKTKLNIDAALDNLALSFANKKSKKMARTYLLQNVSRTQDQQVAISGTYILYTKKHIETSLMLDKTKLVKQILEYAETPNLLGYTDVRDLECLLWLVFCGPKSFCQSDSCFGYSKTGYNAAFPNLLPPYLYECGQNNGLFFGIVQAYVFSWYSDFDFSALEISERARRRIRSLLYDLKQKFSEQEISVLPVASQMCIFCALYKQNKLSLEYVSGDLKTSVFSPIIIKDCLCVQTTISTTQMLPGTKSSAIFPVYDLRKLLSALVISEGSVRFDI
What are the official names of this protein?
Protein U67.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL95 family.
Protein: HISZ_LACPL
Sequence: MLKHLLPLGTRDEFGRRARTKQHLIAVIQAHFKQRGLAPIATPLLENEAVFDPYQMGNYQLYRLFGNDGRTLVLRPDMTLPVARFISATNVPLPQKFGYVGDIFRVSRQLSGSYNQITQAGVELVGYASLKAEFECLTIANQLSSELIADAVEIELGDAQFAQRVVASLTGDEGEQQAILTALFDKQVPRYTKLIAKYRAQPLYDFLKAWPRLFGRPECIFKELAAAPLPETVQPSLKRLQTVVAWMQQTMPEQVISVDLSSQAPQKYYTGLTFRGYSQAGAGYLFSGGRYDKLLTNFQAEAEPAVGMGLNVDLLTTLATDQQTAYAEQLIYFEPEQWSQAEAYLAKQPHAILSLADDLAGARIEAQRLNAQLIDLTGGMTND
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIQ_AQUAE
Sequence: MEQDLIVSLGQRALEMTLLLALPVLLSTFVVGLVVSIFQAATQIQEMTLSYIPKVITAFLVIFLLGGWMMRKLVDFAVEIFANIPVWIR
What is the function of this protein?
Role in flagellar biosynthesis.
What are the official names of this protein?
Flagellar biosynthetic protein FliQ.
What is the protein family that this protein belongs to?
Belongs to the FliQ/MopD/SpaQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: SSRP_COXBU
Sequence: MNKQISKKPAQRTIALNKKALHDYYVEQRFEAGLVLEGWEVKSIRAGRVQLRDSYVVFKGGEAWLIGAHLSPLPNVAEYMKADPQRSRKLLLNKREIGKLFGAVQKQGLTVVPLDLHWHKNHVKVEIVLAKGKKTHDKRETIKRREWEREKHRVLKSHG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GLMU_VIBC3
Sequence: MKFSTVILAAGKGTRMHSNMPKVLHTLAGKPMVKHVIDTCNNLGAQNIHLVYGHGGDQMQQALVNESVNWVLQAQQLGTGHAVDQASPHFQDDEKILVLYGDVPLISEDTIESLLEAQPTDGIALLTVVLEDPTGYGRIVRKRGPVVAIVEQKDASEEQKLIKEVNTGVLVATGRDLKRWLAGLNNNNAQGEYYLTDVIAAAHDEGRAVEAVHPSHSIEVEGVNDRIQLARLERAFQARQAKKLLEQGVMLRDPARFDLRGTLQCGSDVEIDVNVIIEGNVSIGNNVVIGAGSILKDCEIDDNTVIRPYSVIEGATVGENCTVGPFTRLRPGAELRDDAHVGNFVEMKNARLGEGSKANHLTYLGDAEIGKGVNVGAGVITCNYDGANKHKTVIGDDVFVGSDCQLVAPVTIGNGATIGAGTTLTKNVAEGELVITRAPERKIAGWQRPAKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_BACC1
Sequence: MTQYTPMIQQYLKVKADYQDAFLFFRLGDFYEMFFEDAVKAAHELEITLTSRDGGSSERIPMCGVPYHAAKNYIEQLVEKGYKVAVCEQVEDPKTAKGVVRREVVQLITPGTMMEGRTIDEKENNFLAALTHFEDGSYALACNDLTTGQNTVTLLTGSVEDILLEVYATGSKEIVVDSSFSKDELNKLTETLKMTISYEDATAIPEGLEHLVKNVSQAKLIKAVGRLFNYVIRTQKRSLDHLQPVEIYYTNQFMKIDVHSKRNLELTETLRTKEKTGSLLWLLDKTKTAMGGRMLKQWMERPLIQKERIEERLEMVETFVNDYFLREDLKEKLKEVYDLERLAGKVAFGNVNARDLLQLRRSLLQVPAILEAISLLDNAYAARLIQGADPCESLTELLGRSIQENPPLSIKDGDIIKDGYNDKLDQYRYVSKNGKTWIAELEKRERDITGIKSLKIGYNRIFGYYIEVTKANLGALPEGRYERKQTLANAERFITDELKEKETLILEAEEKIVQLEYDLFTALREEVKVFIPKLQHLAKVISELDVLQSFATVSEEEQFVKPVLTTKREIFIKDGRHPVVEKVLNGKLYVPNDCIMPENMDVFLITGPNMSGKSTYMRQLALVTVMSQIGCFVPATEAVLPVFDQIFTRIGAADDLISGQSTFMVEMLEAKNAIANASERSLILFDEIGRGTSTYDGMALAQAIIEHIHDQIGAKTLFSTHYHELTVLEESLDQLKNVHVSAIEENGKVVFLHKIQDGAADKSYGIHVAQLAELPDSLIARAKEVLAQLEGQEEIIIPKRVEVKMQEQEVIPEPVVVKEAPVEIEETKVENEEESQLSFFGGEQSPKKQDKPVLDTKETAVLAQIKKIDLLDMTPLEAMNELYRLQKKLKKG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GRCA_YERP3
Sequence: MITGIQITKANNEALLNSFWLLDDEKAELRCVCAKSGYAEDQIVPTSELGEIEYREVPLEVQPTVRVEGGQHLNVNVLSRDTLEDAVKNPEKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: RHLB_KLEP7
Sequence: MSKTHLTEQKFSDFALHPAVIEALEKKGFHNCTPIQALALPLTLEGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRQVNQPRALIMAPTRELAVQIHADAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPATQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLLEEEWPDRAIVFANTKHRCEDIWGHLAADGHRVGLLTGDVAQKKRLRILEEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTDLPKPLRLTRARPGNGPRRNGPPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.