PharMolix/UniProtQA huggingface dataset:
Protein: COAX_CLOPS
Sequence: MILLIDVGNTNIVLGIHDNEKYIASWRISTDSKKTSDEYSIQVMQLFNQAKLNPEEVEGIIISSVVPNIMHSLENMVRKCFCKEPIVVGPGIKTGINIKYDNPKEVGADRIVNAVAAFEKHKKPMIIIDFGTATTFCAITEKGDYLGGNICPGIQISADALFERAAKLPRIELEKPKSVICKNTVTSMQAGIIYGYIGKVEYIVKRMKKEMMDLGEKEPFVLATGGLAKLVYSETDVIDEVDRKLTLEGLKILYEKNKE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG18_CRYNJ
Sequence: MSRLAKRHPDLLSCNFNQDYSCIAVGHKKGYTILNCDPFGKVHSNNDQGATGIVEMLFCTSLVALVGAAENQPSNSPRKLQIVNTKRQSTICELIFPTSVLAVKMNRKRLIVVLENEIYIYDISTMKLLHTIETGPNPNAVCALSSSSERSYLAYPSPVPSASSTPLSSSAIPAPPPAPTTGDVLLFDTISLTALNVIQAHKTPIAALALNSTGTMLATASDKGTVVRVFSVPDAKKLWQFRRGSSSARIFSINFNLMSTLLAVSSDTSTIHIYRLASSRKGGKDADDASTEEARSPTPSETPLASSPPLAAGKLDSHSAASSLRRRSYHLGKSFVGGVGGYLPKSVSEMWEPQRDFAFIKLRGNHGRTVVAMSATVPQVMVISSEGLFQAYNIDLENGGECSLMKEFALLGSEDFGNGSNGI
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: CMOA_HELPJ
Sequence: MKDTLFNESLNKRFCFDEKVAHVFDDMLERSIPYYHEMLNLGAYFIAQNLKENVYHKSLPKPLIYDLGCSTGNFFIALNQQIQQDIELVGIDNSMPMLKKAQEKLKDFNNVRFECMDFLEVKFKEASAFSLLFVLQFVRPMQREVLLKKIYNSLALNGVLLVGEKIMSEDRILDKQMIELYYLYKQNQGYSHNEIAFKREALENVLVPYSLKENIALLESVGFKHVEALFKWVNFTLLVARKT
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: NTPTH_THEAC
Sequence: MIPLAIKIGITGPVGSIKSEALQKIIDMLKNDNLNVQGVLVSKVTNNGKLTGYTIEDIESKRKAQFCFDNFVSRVKIDKLGVDTKILEEILIPSLQKARETADVIVIDEIGKLENTTKKVHAEIEETLKCGKPLIVTLHKRSRNPVLQEIKSLEGVRVFDITPINKNILPFKVMHVLKGEE
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  May hydrolyze nucleoside diphosphates with lower efficiency.
What are the official names of this protein?
Nucleoside-triphosphatase THEP1, NTPase THEP1, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.
Protein: EFTS_MYCGE
Sequence: MATKIELIKELRKSTQASVMDCKQALEKNNDDFEKAVKWLRENGIVKSTKKLNKVASEGIIVLKSNLHKAIMVEINSQTDFVAKNQELKEFSDLMLEKIFEKVNPKTELVEIEKIQINNDEKVSEKLALIASKTDEKIVLRRVVVFETKTNQIFTYLHANKRIGVIIEIQGKLNEDDGKHLAMHIAANSPQFIDQSDVNQTWLQNERNIIRSQAELEVKENPKKAIFLEKTIEGRVNKLLIDTCLINQKYLIDETKTIGQFLKEKQAKVLKFIRYEVGEGIIKETVDFVSEVNAQIKQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_COXBU
Sequence: MKIRPLHDRVVVRRLEEERTSAGGIVIPDSAAEKPSRGEVISVGPGKPLDNGEVRSLDVKVGDQILFGKYAGTEVKLAGDEYIVMREDDIMGVIEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10, Heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDH1_STAES
Sequence: MKAIGFKSSFQLDEGNCFEEFNFDIPHPSGHELLVKVQSISVNPVDTKQRTMPVDKVPRVLGFDAVGVIEKIGDQVSMFQEGDVVFYSGSPNQNGSNEEYQLIEEYLVAKAPTNLKSEQAASLPLTGLTAYETLFDVFGISKEPSENKGKSLLIINGAGGVGSIATQIAKFYGLKVITTASREDTIKWSVNMGADVVLNHKKDLSQQFKDNHIEGVDYIFCTFDTDMYYEMMVNLVKPRGHIATIVAFNSQQDLNLLKSKSVTFTHEFMFSRPLHHTDDVIKHHEYLKDITEKVEQGYYQPTTTKVIDGLDVDSLYEAHQILESHSMIGKLVINLK
What are the official names of this protein?
Zinc-type alcohol dehydrogenase-like protein SE_1777.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: RL28_SYNP2
Sequence: MSRKCQITGKKANNAMAVSHSHRRTKKLQEVNLQWKRVWWPEGNRFVRLRLSTKAIKTLEKKGIDAMAREAGINLNKL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: SPX3_MOUSE
Sequence: MAWPRFLQRGALLTSFSHHHLAVFLLTFFSYSLLHASRKTFSNVKVSISKQWTPNAFNTSLDLPAEIWSSNHLFPSTEEATLFLGTLDTVFLFSYAVGLFISGIIGDRLNLRWVLSFGMCSSAFVVFVFGTLTEWLHFYNKWFYCGLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACASVGNILGAFLASSVLQYGYEYAFLVTASVQFAGGIIIFFGLLVSPEEIGLPSIGAEESSEEDSQRPLIDGAENEDDYEPNYSIQEDRAVVQVKAISFHQACCLPGVIPYSLAYACLKLVNYSFFFWLPFYLSNNFGWKEAEADKLSIWYDVGGIIGGTLLGFISDVLQKRAPVLALSLFLAVWSLVGYSRSPNNKSINALLMTITGFFIGGPSNMVSSAISADLGRQELIQGNSEALATVTGIVDGTGSIGAAVGQYLVSLIQDNLGWMWVFYFFILMTSCTILFILPLIVREVFSLVQRRQAHSLNE
What is the function of this protein?
Unlike the other SLC37 members, lacks glucose-6-phosphate antiporter activity (By similarity).  In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containg-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol (PubMed:29745899).
What are the official names of this protein?
Sugar phosphate exchanger 3, Solute carrier family 37 member 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DER_STRP8
Sequence: MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIVENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQRLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL34_CHLT3
Sequence: MKRTYQPHNRKRRNKHGFRSRMATKNGRKVLSARRAKGRHRLTVSSETSNKK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL18_TROWT
Sequence: MSLTSRASARKRRHVRLRKKISGTCDRPRLSVTRSNRHVFVQAVDDISGKTLVSASTMEKDIRALELGKTERALAVGKLVAQRALAVGVKSAVFDRGGCKYTGRVAAVAEGAREAGLQT
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SAHH_POLAQ
Sequence: MNTVSDLNNFVATRCAIADISLSDFGRKEIAIAETEMPGLIAIRDEFAAQQPLRGARITGSLHMTIQTAVLIETLEALGAEVQWASCNIFSTQDHAAAAIAANGTPVFAIKGETLEQYWDFTHRIFEWADGGYTNMILDDGGDATLLLHLGARAEKDQACLNNPTSEEETILFAAIKKKLAQDPTWYSTRLEKVKGVTEETTTGVHRLYQMFAKGELKFPAINVNDSVTKSKFDNLYGCRESLVDAIKRATDVMVAGKVAVVCGYGDVGKGSAQALRALSAQVWVTEVDPICALQAAMEGYRVVTMDYAADKADIFVSATGNYHVITHDHMAKMKNQAIVCNIGHFDNEIDVAGIEKYKWEEIKPQVDHVIFPAANGKPEKRIIILAKGRLVNLGCGTGHPSYVMSSSFANQVIAQIELWNAVGTDKYPIGVYTLPKHLDEKVARLQLKTLNAELTVLSDQQASYIGVTKEGPYKADHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRL_PIG
Sequence: MDNRGSSQKGSLLLLLLLVSNLFLCKSVASLPICPSGAVNCQVSLRDLFDRAVILSHYIHNLSSEMFNEFDKRYAQGRGFITKAINSCHTSSLSTPEDKEQAQQIHHEVLLNLILRVLRSWNDPLYHLVTEVRGMQEAPDAILSRAIEIEEQNKRLLEGMEKIVGQVHPGIKENEVYSVWSGLPSLQMADEDTRLFAFYNLLHCLRRDSHKIDNYLKLLKCRIIYDSNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SOEM_CAEEL
Sequence: MMMTMAADYGSSEGHYDTPWEFLARPNSVRFSTADVRLSTSAAGDAKVSPHGSPSLCSSSSFVNQLVQIGNSAVDARRKVPRDESKRRRPSDSEIYMEQNMNRVEAEKRLENRNLGDYLLRSRGEGSAALSLRATKGVVHIKIEWNGEKWVIGEGPLFRSISSAISFYRRHPLPIRGADHLVLKNQLKPV
What is the function of this protein?
Functions downstream of migratory protein mig-13 and may play a role in the control of Q neuroblast migration during larval development.
What are the official names of this protein?
Protein soem-1, Suppressor of ectopic mig-13.
Protein: FBID2_RHOJR
Sequence: MSDYGEWAVIVPFRSLDVAKSRLAVSCRRDLALAFLQDTLAALTLSNHISSVIVVSRNAALSETIGTPVIKDQGSGIDDAVEIGHRWLREHGHDGHYSVVMPDLPALRTGDIDNFLSAASRFPRAFVADSAGTGTTCLTTQQAAILSAFGRNSAQRHTRMGYKQIPLGLPSLRLDVDTIDDLERAARMGVGRHTQRLLISNNELHSLRFPCAPG
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase 2, PEP guanylyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: AROC_TRIEI
Sequence: MGNIFGHLFRVTTFGESHGGGVGVIIDGCPPKLEINVKEIQYELDRRRPGQSKITTPRKESDTCEILSGVFEGQTLGTPIMIWVRNKDARPQDYQDMAIKYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVASGAIAKKILQQYSGVEIVGYVKRIKNLEAIVDPTTVTMEQVESNIVRCPDSECAEKMIELVEKIRDLGDSVGGVVECIVRNVPKGLGSPVFDKLEADLAKGVMSLPATKGFEIGSGFAGTTMTGSEHNDELYTDKLGEIRTVTNRSGGIQGGISNGENIVLRVAFKPTATIRKEQRTVSRQGEETFLAAKGRHDPCVLPRAVPMVEAMVAIVLCDHLLRHYGQCNTLKSENVYGN
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HIS2_SALRD
Sequence: MKRFEELFAELADKVDRQDPDSGTVQAVQEGRHAIGKKVIEEAGEVWMAAEHEGPDRTAEEISQLLYHLQVLMIACDLDLEDVYEHL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_SALTY
Sequence: MKQYAIQPATLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNRLAERFPVHSHPLFIVAESGFGTGLNFLTLWQAFDSFRSAHPQATLQRLHFISFEKFPLTRDDLALAHQHWPELAPWAEQLQAQWPLPLPGCHRLLLDRGRVTLDLWFGDINELTDQLDATLNQTVDAWFLDGFAPAKNPDMWTPNLFNAMARLARPGATLATFTSAGFVRRGLQEAGFTMQKRKGFGRKREMLCGVMEQHLMPTLSAPWFYRSGSEKRETAIIGGGIASALLSLALLRRGWQVTLYCADDQPAQGASGNRQGALYPLLSKHDAAINRFFPTAFTFARRLYDALPVSFDHDWCGVTQLGWDEKSQQKIAQMLSLALPAGLASALNAEEAEQAVGVTTRCGGITYPAGGWLCPEQLTRAVIALATEQGLQTRFRHTLTSLVAQESRWQLRFTSGETASHETVVLANGHQINRFDQTQPLPVYAVGGQVSHIPTTPALSALRQVLCYDGYLTPQNPHNQQHCIGASYHRGDESTVWREEDQRQNRQRLLDCFPDAKWATEVDVSGNSARCGVRCATRDHLPMVGNVPDYHATLTHYADLADNKTSAAPAPVYPGLFMLGALGSRGLCSAPLCAEILAAQMSNEPIPLDAGTLAALNPNRLWVRKLLKGKAVK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAT_WIGBR
Sequence: MKFFIELNKFRLIIVFIVCTSLIGCETINTFVKKRNLEVNTYMNKTIYLNPSEDKTVYIQVKNTSNREINGIKTKISSILKSKGYLITYYPEEANYWIQANILRIEQIKLENKDNLLHHCLEQYLDDIHHTPGLCNKENEEENNFIEKISKSFFENNNFIVVTDLQISQRTNILCSKFDRFHLNSKEKIKNVINPKSKEGKRNFYKTRIYSYANKVNLEFYEAKKEIENQISHSISEVF
What is the function of this protein?
Responsible for preventing unproductive conjugation between bacteria carrying like plasmids.
What are the official names of this protein?
TraT complement resistance protein.
What is the protein family that this protein belongs to?
Belongs to the TraT lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: STABP_RAT
Sequence: MSDHADVSLPPQDRVRILSQLGSAVELNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKSAIIPEKKDAVKKLKNVAFPKAEELKTELLKRYTKEYEQYKERKKKEEEELARNIAIQQELEKEKQRVAQQKQKQLEQEQFHAFEKMIQKQELEKERLKIVQEFGKVDPGPCGPLLPDLEKPCVDVAPSSPFSPTQTSDCNTTLRPAKPPVVDRSLKPGALSVIENVPTIEGLRHIVVPRNLCSEFLQLASANTAKGIETCGVLCGKLMRNEFTITHVLIPRQNGGPDYCHTENEEEIFFMQDDLGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFKLTDYGLQEISTCRQKGFHPHGRDPPLFCDCSHVTVKDRIVTITDLR
What is the function of this protein?
Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains.  Does not cleave 'Lys-48'-linked polyubiquitin chains.  Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF.  Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7.  Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes.  Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization.  Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
What are the official names of this protein?
STAM-binding protein, Associated molecule with the SH3 domain of STAM.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67C family.
What are the subcellular locations of this protein?
Nucleus. Membrane; Peripheral membrane protein. Cytoplasm. Early endosome.
Protein: G3ST3_BOVIN
Sequence: MPPIFQRLQQATKMSRRKILLLVLGCSTLSLLIHQGAQLSWYPKLFPLSCPPLQDSPPRPKHMTVAFLKTHKTAGTTVQNILFRFAERHNLTVALPHPSCEHQFCYPRNFSAHFVHPATRPPHVLASHLRFDRAELQRLMPPGTVYVTILREPAAMFESLFSYYNQYCPAFRRVPNASLEAFLRAPEAYYRAGEHFAMFAHNTLAYDLGGDNERSPRDDDAYLAGLIRQVEEVFSLVMIAEYFDESLVLLRRLLAWDLDDVLYARLNARAASSRLAAIPAALAQAARAWNALDAGLYDHFNATFWRRVASAGRACVEREARELREARERLLRRCFGDEPVLRPAAQIRTKQLQPWQPSRKVDIMGYDLPSGRAGPATEACLKLAMPEVQYSSYLLRKQKRRGGMRLRPEPVLDNPPPRPIRALRPGH
What is the function of this protein?
Transfers a sulfate to position 3 of non-reducing beta-galactosyl residues in N-glycans and core2-branched O-glycans.  Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha-1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha-1,4)GlcNAc (By similarity).
What are the official names of this protein?
Galactose-3-O-sulfotransferase 3, Gal3ST-3, Beta-galactose-3-O-sulfotransferase 3, Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3.
What is the protein family that this protein belongs to?
Belongs to the galactose-3-O-sulfotransferase family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: FM522_ASPOR
Sequence: MTTAAVFGSTGAVGGQILATLLASDAFSSVKTVSRRLPNAQSPKLQTLEEGDITKWGGLIASLSPKPSIVFNAVGTTRAAAGGIANQWKIDHDLCIENAKAAKEAGVKTYVFISSGGTRGFFSRYVPYSKMKIGVEDAIKELDFEQAIILRPGLILQREKPKAALLENIVQNLNKLGQGVQDMIGQDQTVIGRAAVAAARMAEEGKAPSKYWVLEQADIVRLGRDEWKQ
What are the official names of this protein?
Protein fmp52-2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: CRYAA_EUDEL
Sequence: RALGPLIPSRLFDQFFGEGLLEYDLLPLFSSTISPYYRQSLFRSVLESGISEVRSDREKFTIMLDVKHFSPEDLSVKIIDDFVEIHGKHSERQDDHGYISREFHRRYRLPSNVDQSAITCSLSSDGMLTFSGPKVQANMDPSHSERPIP
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock.
Protein: SYN_THEKO
Sequence: MIDKVYCADVTPEMEGKKVKLAGWVYRKREVGKKVFIVLRDSSGIVQVVFSKDLNEEAYREAKKVGIESSVIIEGTVKADPRAPTGAEVQGEKLQIIQNVDFFPITKDASDEFLLDVRHLHLRSPKVAAIMKVKGTLMQAAREWLLQDGWYEVFPPILVTGAVEGGATLFKLKYFDRYAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIELYRKDDIKTLKNAVPPFPRISYDEAIDILQSKGVNIEWGEDMGADEERVLTEEFESPFFVYGYPKHIKAFYMKEDPEDPRKVLAADMLAPEGYGEIIGGSQREDDYDKLVQRILEEGMKPEDYEWYLDLRKYGSVPHSGFGLGLERLVAWVLKLDHVRWATLFPRTPSRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XNI_VIBCH
Sequence: MSLHLVIIDALNLIRRVHSAQPDPNDITRTAETTTRTLQRIINEAQPSHMIAVFDHHLSDRGWRAELLPTYKANRKPMPDVLQQGIDAIQDAWWQLGIDSLLSEGDEADDLVATLACKVAAHQEKVTIISTDKGYCQLLSPTLQIRDYFQQRWLDEPFIAQEFGVTPAQLTDYWGLTGVSSSQIPGVAGIGPKAAKEILNQFSSIEEAYASPELPAKYRKKLDPHIEMARICKQVSALKTDIELGFNLQDIRFNSSSAD
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: GSIA_SALPA
Sequence: MPHSDELDSRDVLSVSGLNIAFHHEGQQIDAVRNVSLRLKRGETLAIVGESGSGKSVTALALMRLIEQSGANVRCGEMLLRRRNRQVIELSEQSDAQMRRVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEALAEAKRMLDQVRIPESQAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQEMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPTHPYTQTLLAAVPQLGAMRGHSLPRRFPLISADEPALYESQIEQDTVVEGEPILQVRGLVTRFPLRSGLFNRVTREVHAVENISFDLWPGETLSLVGESGSGKSTTGRALLRLVESRQGEIIFNGQRIDSLSAGKLQPLRRDIQCIFQDPYASLDPRQTVGYSIMEPLRIHGLGQGDAAAKRVAWLLERVGLRPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSVRGQIINLLLDLQREMGIAYLFISHDMAVVERISHRVAVMYLGQIVEMGPRRAVFENPQHPYTRKLMAAVPVADPSRHRPRRVLLSDDIPSNIHKRGEETPAVSLQLVGPGHYVARPLQDNALSRL
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutathione import ATP-binding protein GsiA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ISCS_ECO27
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_GEOSL
Sequence: MAEKELAKVYEPTAVERKWYETWEQEGYFRANPDSGKPSYSIVIPPPNVTGALHMGHALNNTLQDILCRWKRMNGYEVLWMPGTDHAGIATQNVVERQLAGEGTSRHELGREAFIERVWKWKAESGGQIIGQLKRLGASCDWGRERFTMDEGLSRAVREVFVRLYEEGLIYRDNRLINWCPRCHTALSDIEVEHEDKAGNLWHIRYPVVGEPGRFVVVATTRPETMLGDTAVAVHPEDERYADLVGKKVLLPLVNREIPVVADGYVDREFGTGVVKITPAHDFNDFEVGRRHNLDLLNVFDESAVVNSAGHQYEGMERFAARKRVVEDLEALGLLEKIDDHAHAVGGCYRCKTVVEPYLSLQWYVKVGPLAERALAAVKDGRTRIVPQQWENTYYDWMENIKDWCISRQIWWGHRIPAWYCDHCGETTVAKIDPTVCAACGSDEIRQETDVLDTWFSSALWPFSTMGWPDRTPELAAFYPTSCLVTGFDILFFWVARMMMMGLHFMNEVPFSDVYIHALVRDAQGQKMSKSKGNVIDPLVVIDQYGTDAFRFTLAAFAAQGRDIKLAEERIAGYRNFVNKIWNASRFALMNLEGFEPDTVDPATLDLSNADRWILHRLNSAAAETAEALEAYRFNDAAGTLYRFTWSEFCDWYIELAKDDLYRGDDARKETARYVLWLVLENLLRLLHPFMPFITEEIWQTLPGARPAPSIMVAGYPRSVPERDFPDGAAEMELVMEVIRGIRNIRGEMDVAPSREIAAILSCGSAESLHLLKRNEVYVMSLARLSDLAIGQQLERPADAAIQVAGDVEIAVPLKGLVNVEEEEKRLLKEIGKLDKEIEMFGRKLENPSFVERAPADVVAKEREKLAEVTQKKDVLLASLEKIRKLA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.