PharMolix/UniProtQA huggingface dataset:
Protein: YAN8_YEAST
Sequence: MPQVQSWFPVQKQPTLAVTFTPLPQLSHAHLPLPPSHLVTKTDAMFQHQLLPTQLQPFPPSHTPLLLLLTVTTMAVTPRLSLLNVLKKLQQPPFLQNHTLLLPLLTVTTTAVTPRLSLPRLPNKHHWPLAQSPSLLLQLLILLLPAPSLVLSFNPKVWLLV
What are the official names of this protein?
Uncharacterized protein YAR068W.
Protein: DNJC2_MOUSE
Sequence: MLLLPSAAEGQGTAITHALTSASSVCQVEPVGRWFEAFVKRRNRNASTSFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFQVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERKWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEARRKEQEAKEKQRQAELEAVRLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKSWNHFSDNEADRVKMMEEVEKLCDRLELASLQGLNEILASSTREVGKAALEKQIEEVNEQMRREKEEADARMRQASKNAEKSTGGSGSGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVISKAKSLQKLDPHQKDDINKKAFDKFKKEHGVASQADSAAPSERFEGPCIDSTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRRYKELVEMVKAKKAAQEQVLNASRARK
What is the function of this protein?
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus.  When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state.  In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain.  When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
What are the official names of this protein?
DnaJ homolog subfamily C member 2, Mouse Id associate 1, MIDA1, Zuotin-related factor 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: FEN1_AJEDR
Sequence: MGIKHLYQVIQENAPDAVKAGEIKNHFGRKVAIDASMSIYSFLVAVRSDGQQLMSETGETTSHLMGMFYRTLRIVENGIKPVYVFDGAPPKLKSGELAKRFMRKSEAAEAHEEAKEVGTAEDVEKFSRRTVRVTREHNEECKKLLKLMGVPYINAPTEAEAQCAVLARAGKVYAAASEDMDTLCFDSPILLRHLTFSEQRKEPILEIHLDRVLEGLDMDRKQFVDLCILLGCDYLDPIPKVGPNTALKLIRDHGSLEKVVEAIQSDPKKKYTIPEDWPYKDARELFFDPDVRKADHPDCNFKWEAPDVEGLVKFLVEEKAFSEDRVRNGAARLQKNLKTAQQSRLEGFFKPIAKTEQEKATLKRKHEEKLELQKKKKKEEAKAKKEAKSKPRGAV
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: VG88_BPML5
Sequence: MAKLKRSNDRKVTNYVHVTKGGNATVGIANSIGLPSGQGFSCPDATAFCAKVCYAGKLEKVRKAVSSVLLHNWELLRDADLTDTVTLLSEMVAEFVKDCDRRKAPKLFRIHWDGDFFSPTYVAAWGRVIRDNPDVQFWAYTRVQTAAVYLHSQRLDNLALYFSADPDNIDVARFLEDKGINIAYVDTTFAKGKAEFPTAVRCPENNKAIDLINDKGSACARCGLCVNGRRNVLFSTTKK
What are the official names of this protein?
Gene 88 protein, Gp88.
Protein: RIMM_CAMFF
Sequence: MKSDFVEVCILGKTVGLKGALKLHDRSDFPNQFKNGAKFYDINSKEFVIKSYDRNNNLVIFENYDSIDLAKTLVNYILYRSINDTIRDCKLAKDEFFYFDIIGCNVFEDKILLGEVIDILEVGAGFLFSIKTEGDLVKAGLNSNFYIPYNDNFTQNIDIKSKKIQVKNSLDILKNS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_BURO1
Sequence: MSRNELDERIETYYVRVRGVVQGVGFRHATVREAHALKLRGWVANLEDGTVEAMIQGPGAQIDRMLAWLRHGPPAARVTEVTFEERRTEKRFERFQQQ
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: LYTT_BACSU
Sequence: MLRVLIVDDEMLARDELAYLLKRTNDEMEINEAENIESAFDQMMDQKPDLLFLDVDLSGENGFDIAKRLKKMKHPPAIVFATAYDQYALKAFEVDALDYLTKPFDEERIQQTLKKYKKVNRDIVETEQNSHAGQHKLALSVGESIVIVDTKDIIYAGTEDGHVNVKTFDHSYTVSDTLVVIEKKLPDSDFIRVHRSFVVNTEYIKEIQPWFNSTYNLIMKDGSKIPVSRTYAKELKKLLHI
What is the function of this protein?
Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
What are the official names of this protein?
Sensory transduction protein LytT.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAIT1_LIOAU
Sequence: DFPLSKEYETCVRPRKCQPPLKCNKAQICVDPKKGW
What is the function of this protein?
Affects the activity of both ryanodine-sensitive calcium-release channels RyR1 and RyR2 with high potency.  At lower concentrations the toxin increases full openings of the RyRs, and at higher concentrations it inhibits full openings and induce openings to subconductance levels and reduces the number of full conductance openings.  The different actions may be attributed to the toxins binding at different sites on the RyRs, with binding at a high-affinity site mediating the increase in full openings and the induction of subconductance states evoked upon binding to a lower-affinity site (By similarity).  Shows insect lethality against crickets and common cutworms (only shows paralysis against cockroaches), but no toxicity is observed in mice.
What are the official names of this protein?
Insecticidal toxin LaIT1.
What are the subcellular locations of this protein?
Secreted.
Protein: ANKR1_RAT
Sequence: MMVFRVEELVTGKKNSNGSSGEFLPGEFRNGEYEAAVALEKQEDLKTLPANSVNLGEEQRKSEKVREAELKKKKLEQRSKLENLEDLEIIVQLKKRKKYKKTKVPVVKEPEPEIITEPVDVPRFLKAALENKLPVVEKFLSDKNSPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLNVKNCAGKTPMDLVLHWQNGTKAIFDSLKENAYKNSRIATF
What is the function of this protein?
May play an important role in endothelial cell activation.  May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 1, Cardiac adriamycin-responsive protein, Cardiac ankyrin repeat protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNFE_PSEA6
Sequence: MNEFKQLSWQGLWKNNPALVQLLGLCPLLAVTATVTNGLGLGLATTLVLIGSNATVSIIRNLVPNEIRIPIFVMIIAAFVTVVQLLMNAYTYELYQALGIFIPLIVTNCAIIGRAEAYASKNPIGYAAFDGLMMGLGFTVVLVLLGAMRELLGYGTLFAGANLLLGDWATSLKVTIFTTDSPFLLAILPPGAFLGMGLLIAAKNILDKRFERMFAAKQEAKVVQRARVTAET
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVC_PSECP
Sequence: MTLRVLGVDPGLTRCGIGVVDVERNRRATMVAVGVVGTSPDESLDQRLLVIATAIDEWLDRYEPQVLAVERVFSQLNVSTVMGVAQASGVVIAAAARRGIPVALHTPSEVKAAVTGSGSSNKDAVTKLVTKILRLDAPPRPADAADALALAITHAWRAGSGASVATTGPGSSSLTPAQRAWAEAEAKARRAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ATX10_MOUSE
Sequence: MAAPRMPPSRLSGIMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSTHAVELACRDPSQVEHLASSLQLITECFRCLRNACIECSVNQNSIRNLDTIGVAVDLVLLFRELRVEQDSLLTAFRCGLQFLGNVASRNEESQSIVWVHAFPELFMSCLNHPDKKIVAYCSMILFTSLNAERMKDLEENLNIAINVIEAHQKHPASEWPFLIISDHFLKSPELVEAMYGKLSNQERITLLDIVIAKLVGEEQLTKDDISIFVRHAELIANSFMDQCRNVLKLTSEPHTEDKEALVTIRLLDVLCEMTSNTELLGYLQVFPGLMERVIDVLRVIHEVGKESTNIFSPSDSLKAEGDIEHMTEGFKSHLIRLIGNLCYKNKENQDKVNELDGIPLILDSSNIDDNNPFMMQWVVYAVRNLTEDNSQNQDVIAKMEEQGLADASLLKKMGFEIEKSGDKLILKSNNDIPPP
What is the function of this protein?
Necessary for the survival of cerebellar neurons.  Induces neuritogenesis by activating the Ras-MAP kinase pathway.  May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
What are the official names of this protein?
Ataxin-10, Brain protein E46, Spinocerebellar ataxia type 10 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ataxin-10 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: DPH2_PONAB
Sequence: MESMFSSPAEAALQREAGMPGLLTPLPDLDRVYELERVAGFVRDLGCERVALQFPDQLLGDAVAVAARLEETTGSKMFILGDTAYGSCCVDVLGAEQAGAQAVIHFGPACLSPPARPLPVTFVLCRRSVALELCVKAFEAQNPDPKAPVVLLSEPACAHALEALATLLRPRYLDLLVSSPAFPLPVGSLSPEPKPLERFGRRFPLAPGRRLEEYGAFYVGGSKASPDPDLDPDLSRLLLGWAPGQPFSSCCPDTGKTQDEGARAGRLRARRRYLVERARDARVVGLLVGTLGVAQHREALAHLRNLTQAAGKRSYVLALGRPTPAKLANFPEVDVFVLLACPLGALAPQLSGSFFQPILAPCELEAACNPAWPPPGLAPHLTHYADLLPGSPFHVPLPPSESELWETPDVSLITGDLRPPPAWKSSNDHGSLALTPRPQLELAESSPAASFLSSRSWQGLEPRLGQTPVTEAVSGRRGIAIAYEDEGSG
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
Protein: EFP_PASMU
Sequence: MATYTTSDFKPGLKFMQDGEPCVIVENEFVKPGKGQAFTRTRIRKLISGKVLDVNFKSGTSVEAADVMDLNLTYSYKDDAFWYFMHPETFEQYSADAKAIGDAEKWLLDQADCIVTLWNGAPISVTPPNFVELEIIDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G2OX1_PEA
Sequence: MVLLSKPTSEQYTYVRNNMPITFSSSIPLVDLSKPDAKTLIVKACEDFGFFKVINHGIPLDAISQLESEAFKFFSLPQTEKEKAGPANPFGYGNKRIGLNGDIGWIEYLLLTTNQDHNFSLYGEDIDKFRGLLKDYKCAMRNMACEILDLMAEGLKIQPKNVFSKLVMDKQSDCLFRVNHYPACPELAINGENLIGFGEHTDPQIISILRSNNTSGFQISLRDGSWISVPPDHSSFFINVGDSLQVMTNGRFKSVRHRVLANGIDPRLSMIYFCGPPLSEKIAPLPSLMKGKESLYKEFTWFEYKSSTYGSRLADNRLGNYERIAAT
What is the function of this protein?
Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level.  Catabolism of gibberellins (GAs) plays a central role in plant development.  Converts GA9/GA20 to GA51/GA29 and GA4/GA1 to GA34/GA8.
What are the official names of this protein?
Gibberellin 2-beta-dioxygenase 1, GA 2-oxidase 1, Gibberellin 2-beta-hydroxylase 1, Gibberellin 2-oxidase 1, Protein SLENDER.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily.
Protein: CYSC_AERHH
Sequence: MSNIVWHAHAVDKQSRAEQKGQKPLVIWFTGLSGAGKSTLAGALEQALAASGKHTYLLDGDNVRHGLCGDLGFDDAARQENIRRVGEVAKLMVDAGLIVLTAFISPFRAERELVRNLVGEGEFVEVFVDAPLSVCEERDPKGLYKKARAGEIRNFTGIDSAYEAPEQPEIHLLNAGKPVAALVDELLTALRLRVLID
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: DCUP_NOCSJ
Sequence: MTPDPRLADSAFLKAARGEPVPHTPVWYMRQAGRSLPEYLAVREGIGMLESCMDPDLVVEITLQPVRRYGVDAAIFFSDIVLPLKAVGVDLDIKPGVGPVVAHPVRTLADVEAIPDLTPEHVPFITEAVRGLVGELGGTPLIGFAGAPFTVASYLVEGGPSKEHARTKAMMFGAPDVWDALLRKIAGISASYLEVQVAAGASAVQLFDSWAGALTPADYRAFVMPHSARVLERAGALGVPRIHFGVGTANLLGLMGEAGADVVGVDWRTPLAHAIALVGDRGVQGNLDPTLVFAPTEVMTARAAEIVEAGRAARGHIFNLGHGVIPSTDPDQLKRLTEFVQTYPR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_SHEPC
Sequence: MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANVASTHSADVPEADTGVPAAVAASKNLITVKTDQLDVQINPVGGDIVFAALVSHKMEQGKEQPFVLLEQTKDYTYIAQSGLIGRDGIDSSANGRAAFTTSATEFTLAEGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMMMPTYRGGAFSTNDVRYEKYNFDDMAKSNLNQATLGGWAAMLQHYFVSAWVPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGASQEISSQFYVGPKDQAALSAISETLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGVAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLADLKERFGDDRQKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFIMQKMQPIAPTMDPMQVKMMQWMPVIFTVFFLWFPSGLVLYWLVGNIVAIIQQKIIYAGLEKKGLK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHS2_ORYSJ
Sequence: MVTSTVKLEEVRRMQRAEGMAAVLAIGTATPANCVYQTDYPDYYFRVTNSEHLTNLKERFQRMCESSQIRKRYTHLTEEILQENPSMCVFTAPSLDARQDMVVAEVPKLGKAAAEEAIKEWGQPMSRITHLVFCTTNGVDMPGADYQVAKMLGLPTSVKRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEIMAMAFRGPSESHLDSLVGHALFGDGAAAVIVGSDPDEAADERPLFQIVSASQTILPGTEDAIVGHLREVGLTFHLPKDVPEFISDSVEGALTDAFMPLGVHDWNSIFWVVHPGGPAILDQVEEKVALHKARMRASRNVLSEYGNMASATVLFVLDEMRKLSADDGHATTGEGMDWGVLFGFGPGLTVETIVLHSVPITAAAPLIMQ
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 2, OsCHS2, Naregenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RPOC_FRAP2
Sequence: MNNGILHQNYNSKKFDIIKISLASPEVIRSWSHGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVVCERCGVEVEQAKVRRERMGHIDLVCPVVHIWYLKSLPSRIGLFLDMPLKNVEKVLYFESYIVTDPGMTPLEKKQLLTDDEYAEALENYGYEFEASMGAEAIRDLLADTDLETEIESLQAEYEESKSTAKKEKAIKRLRLLETFQASGNKPEWMVMTVLPVLPPDLRPLVPIEGGRFATSDLNDLYRRVINRNNRLKKLLDLNAPDIIVRNEKRMLQEAVDALLDNGRRGRAVTGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPSLRLHECGLPKKMALELFKPFVYSKLRLGGYATTIKQAKRMVELEEAVVWDILEVVINEHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTVESQLEARVLMMSTNNILSPASGQPIITPTQDIVLGLYYITREKEGARGEGKLFSNYDDVSRAYNSGTIDIHAKIKLRIDRQVFDTKGNTYNEKGVVNTTVGRALLLNILPEGLSFSLLNKVLVKKEISKIINQAFRVLGGKATVVLADKLMYAGFKYSTLSGVSVGVDDMTIPENKEAKVEEAEKEIKHITEQYQSSLITENERYNNIINIWSKTSDEVGASMMDAISKDTVMVNGENKEIESFNSVYMMAKSGARGSYNQMRQLAGMRGLMAKPDGTMIETAITANFREGLSVLQYFTSTHGARKGLADTALKTANAGYLTRRLVDVAQDLVVIEEDCGTDDGLMFSAIVEDGEVKVPLVERALGRTLAADVVTEKGVVLLEAGTLLDENLVEILDDNGIDMIKVRSPITCKTRRGLCAKCYGRDLARERKVNVGESVGVIAAQSIGEPGTQLTMRTFHTGGAASLGITVSDIKVKTAGKIKFKNIRTVTNKDGQNIVISRAGEIIVSDTMGRVREQHKIPMGAVVPLASGKGVEIGDVIATWDPHAQPLITDVAGKVVLEDVIDGITSKHTYDDLTGQQTIEITSISQRTTSKNLKPVVKVVDEKGNEIKSISLAVGAVLNVTDDSVLEVGDVVAKIPLEGSKNKDITGGLPRVAELFEARRPKDAAILSPCDGMVRLGNRDTKEKQRIEILDKSGHIAEEILLPKSRHLVVFDGEQVSKGDVLADGPTDPHDLLKYKGLEAFADYILIEAQSVYRMQGVVINDKHIETIVRQMLRKATILDEGDSKFVKDESIELVRILEENDRLAKEGKRLVEYELTLMGITRSSLSTESFLSAASFQETTRVLTEASIHSQVDQLRGLKENVLIGRLIPTGTGLAVRKESNKIEKMREELGVEDNMIFTEASSFNTEDTLFENQIEKEDKDINDDIEESLRNALESLDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: FER_GUITH
Sequence: MATYKVKLSGEGVDKTIDCPDDQYILDAAEEQGIDLPYSCRAGACSTCAGKVAAGSVDQSDQSFLDDSQIGDGFVLTCVAYPTSDCTILTHQEEGLY
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSIE_YERPB
Sequence: MAKNSRSQWIAKNLQRLLNVGLIMLAAILVVFLVKETIHLGKVLFLSNQETSSYMLIEGIVIYFLYFEFIALIVKYFESGYHFPLRYFIYIGITAIIRLIIVDHENPIDTLIYSGSILVLVVTLYLANTERLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIM_ACIAD
Sequence: MYNSSNIIDYVIDAWEKLQEQAPLVQCITNSVAANYAANVLLAAGASPAMIDNPFEARSFTEISGALSINVGTPTTEQIQAMQISAKTAHEHDIPWVLDPVGYGPILKWRSDMVDELLQYHPSVIRGNASEIGALAGSLVQSKGVDSTLKSDEMFQLAHNLLTKTSCVAISGETDYILSNAMTCIVKVRGGSHLQPKITATGCALGTLIAAYCAVAPVHLATIAAHIHFAIAGKLAYDQAQTIGSFNTMFMDYIHMMDANLIEQYACIELISDD
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RPOZ_AGRRK
Sequence: MARVTVEDCIDKVENRFELVLLASHRARLISQGSSITIDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEIDEPEPDPASLLAAGGNASASGDEEEDAPEAVTFDQMSEEELLAGIEGLVPPEKSDDY
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PURA_PARMW
Sequence: MANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVDDRVLKLHLIPSGILYPETICLIGSGTVVDPKVMLGELDMLIANDIDISGLQLASTAHVTMPYHRLLDLAMEKQRGDRRIGTTGRGIGPTYADKSQRSGIRVIDLLDEARLRERLEGPLQEKNQLLETIYGVEPLDAETVIKEYLGYGKRLAPHVVECTQAIHQAARARKNILFEGAQGTLLDLDHGTYPYVTSSNPVSGGACIGAGVGPTLIDRVIGVAKAYTTRVGEGPFPTELSGRLNDQLTERGGEFGTTTGRRRRCGWFDGVIGRYAVQVNGLDCLAVTKLDVLDELDAIQVCVAYELDGERIEHFPSSAEDFARCNPLFETLPGWQCSTEDCRKLEDLPDAAMAYLRFLADLMEVPIAIVSLGASRDQTIVVEDPIHGPKRALLSA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBTB_MYCPA
Sequence: MVHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFATLAETPTIEAWAQLVTAGRQDTDSAAPPADSSGDPSGETEPFALAPMQHAMWVGRQDNQQLGGVAGHLYVEFDAGLLDSGRLRAAATALARRHPMLRVRFLPDGTQCITPAVECGDFPVHVEDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMSYRTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPPALPITAGRGANRSTRRWHWLDPQTRDALFARAQARGITPAMALAAGFANTLARWSSNSRFLLNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAARAQVVQDAMRTAAAHSAYSGLSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTGQFGTPAWIISQGPQVLLDAQVTEFDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAVREAINGRTAPPSGEALHDRFFRQAERQPDAPAVFAGSGDLSYAQLRDQALAVAAALRAAGAGAGDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRAERILQSGRVRLALVCGGRQLSLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAMNTVEFIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARLIDTHRVTVLHFMPGWLEMLVEVGRGRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGLGGATETPVHNTIFEVTEPIPADWTALPFGVPLPNNVCRVVGDTGGDCPEWVPGELWVSGRGIARGYRGRPDLTAQRFVEHDGRTSYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVELGEIESALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMIPRHVAVVERIGFTAAGKLDRRAVARELHSVVGQSHSPGHRAASTPLEGALALILGDLLGRDDVGVDDDFFALGGDSVLATQAVARIRAWLDAPDVMVADMFANRTVSALAAVLRAAEDDPDRLDHVAELYLEVIGMDAESVLTATRQTTKS
What is the function of this protein?
Involved in the initial steps of the mycobactin biosynthetic pathway.  Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores (By similarity).
What are the official names of this protein?
Phenyloxazoline synthase MbtB, Mycobactin synthetase protein B.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.