PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_AMOA5
Sequence: MQDKVLTDLIKTEKPEQIEDFLPNEEDITSPTITRNLYVESYGCQMNIADSEVVVSILRPHGFEITDTYEKADVIFINTCAIRDKAEQTVRKRLSQFNQLKRRNPDLVIGVLGCMAERLKQTLLEEEKLVDLVAGPDAYRDLPRLLATVDSGHKAINTFLSREETYADISPIRLNSNGVSAFISIMRGCDNMCSFCVVPFTRGRERSRDPYSIVKEATELFEQGYREVTLLGQNVDSYKWSPNTDKKEQPTTPQEGVVNFAQLLAMVAQIHPDLRIRFSTSHPKDITDQVLYTIKAYDNICKYIHLPVQSGSSRVLKLMNRTYDRAWYLQKIEDIRRIVGEDCGISSDMIAGFCTETEEDHQDTLSLMEHIKYEFSYMFYYSERPGTLAARKYADDVPLAVKKRRLQEIIDKQRQHSFEKNLKDIGKVYQVLVEGPSKKSDIEWQGRNSANKVVVFPNVDCKKGTYVDVLITNCTTGTLLGEICTR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_LACAC
Sequence: MNYAEYFTNRSTDEITRDLIGRPLTFNDGQEKLGGYIVEAEAYMGKLDRAAHSYGGHRSPANEGLYRTGGTIYIYAQRQYFFFDVACQEENEPQGVLVRAIDPAWGIDSMIKNRNGKSGVLITNGPAKMMQAFGIHDKNWNLHFLSDSPFTIDLADNHKRIAQEIIADKRVGINQSDPIWANKKLRYYVAGNPYVSDMKKRDYASNNGWT
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: QUEA_ACIAD
Sequence: MQLSDFNFDLPDELIARYPLDTRSASRLLHLDAHGHYHDHAFTDILDLINDGDLLVLNDTKVMKARLKGKRASGGAIEILVERMLDNQIAHCHIKASNTPKAGAELFVGENGIKVTVQGRHENLFVVEFSEPILSVLDRYGQLPIPPYFNREAEEIDTERYQTVFHDPQKIASVAAPTASLHFDQDLLEKLAAKNIQKTFVTLHVGAGTFMPVRTDDIKNHIMHSEWCDVPESTAELIRQTKARGNKVIAVGTTATRALESAAQANGGKIDAWTGDTQIFIYPGYQFCVVDRLITNFHLPESTLLMLVSALSNRNNILSAYEHAVQSKYRFFSYGDAMLIDQAV
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS1_THAPS
Sequence: MKFTAACILLSATAASAFSPVARFTFSRPTTTSLHAEVTTALIKELREATGAGMMDCKKALTEFDGDIEAAADELRKKGLAKADKKASRIAAEGKIAVASAGGKTVLVEVNCETDFVAKDESFAKFADEAAAAAAAMDGDSVEALMAANGNALEDARAGLVSKIGENIQVRRVATRGSGATTTGAYVHMNRIGVLVEIEGGTEALCTDVAMHVAAMNPAYATQEDVPAADIEKERAFLTAQVEDSGKPADIVAKMVEGRLQKFLAENCLVSQTYVKTNDRTVAKLLEENGAKMIGFTRIAVGEGIEKKVDDFAAEVAAMAGGGKAAPAPKAEEPAAVAPAKADAEDSAEAHKLSVITYP
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts 1, mitochondrial, EF-Ts 1, EF-TsMt 1.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GPDA_PELPB
Sequence: MNIAVLGAGSWGTTLAVLLAKKGHDVRLWAHRPEFAATLDAERENRRYLKGVAFPDSLQITPHLQPLVSWSEMIVTAVPSQALRETILGFCTLDLSGKILVNVAKGIEIGTGKRMSEVLLEVLPGVCPSQVAALYGPSHAEEVSKGQPTTVVASSSSLATAEKVQEVFHTSMFRVYVNTDIVGVEIAGSVKNIIAIAAGISDGIGFGDNAKAAIITRGMAEISRLCSKLGGEAVTISGLAGIGDLVVTCLSRHSRNRYVGEEIGRGRSLDEVISQMNMIAEGVHSSRAVYELSRAVGVDMPITRAVYQMLFERKPVEQAILDLMTRDLKQERD
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_AZOVD
Sequence: MSTTETTGKSPAKVETGVKLRGAEKVARIPVKVIPTEELPRKPDWIRVRMPASPEVERIKQLLRQHKLHSVCEEASCPNLGECFAGGTATFMIMGDICTRRCPFCDVGHGRPNPLDPDEPKNLAVAVADLRLKYVVITSVDRDDLRDGGAQHFADCLREIRRLSPGTQLETLVPDYRGRMEIALDITAAEPPDVFNHNLETVPRLYKASRPGADFEWSLDLLEAFKKRVPAVPTKSGLMLGLGETDEEVIEVMKRMREHEIDMLTLGQYLQPSRNHLAVQRFVHPDTFAWFAEEGERMGFKNVTSGPLVRSSYHADQQAHGAKGD
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFI_BACHK
Sequence: MMIMNNFDEKKLIQEFSKIQSELSPRIKLENNFQIEEIQFIAGVDLAYWNVNKTKYGTCCIVIIDYGTKEVVEKVYSYGEIPIPYIPGFLAFRELPLIIEAVKKLTKQPDIYFFDGNGYLHYRHMGIATHASFLLNKPTIGVAKSYLKIRDVDFIMPENLKGSYTDIVINNEVYGRTLRTTKNVKPIFVSCGNWIDLDTSTEIVMNCINNESRLPIPVRLADLETHKMRKKLMEG
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAFA1_NEIG1
Sequence: MRARLLIPILFSVFILSACGTLTGIPSHGGGKRFAVEQELVAASARAAVKDMDLQALHGRKVALYIATMGDQGSGSLTGGRYSIDALIRGEYINSPAVRTDYTYPRYETTAETTSGGLTGLTTSLSTLNAPALSRTQSDGSGSRSSLGLNIGGMGDYRNETLTTNPRDTAFLSHLVQTVFFLRGIDVVSPANADTDVFINIDVFGTIRNRTEMHLYNAETLKAQTKLEYFAVDRTNKKLLIKPKTNAFEAAYKENYALWMGPYKVSKGIKPTEGLMVDFSDIQPYGNHTGNSAPSVEADNSHEGYGYSDEAVRQHRQGQP
What are the official names of this protein?
Adhesin MafA 1/4.
What is the protein family that this protein belongs to?
Belongs to the MafA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PER_DROSI
Sequence: KVSDSAYSNSCSNSQSQRSGSSKSRLSGSHSSGSSGYGGKPSTQASSSDMIIKRNKDKSRKKKKNKGTGQGAGQAQTLISASTSLEGRDEEKPRPSGTGCVEQQICRELQDQQHGEDHSEPQATEQLQQEEEDQSGSESEADRVEGVAKSEAAQSFPIPSPLSVTIVPPSMGGCGGVGHAAGLDSGLAKFDKTWEAGPGKLESMTGVGAAAAGTGQRGERVKEDSFCCVISMHDGIVLYTTPSITDVLGYPRDMWLGRSFIDFVHLKDRATFASQITTGIPIAESRGSVPKDAKSTFCVMLRRYRGLKSGGFGVIGRPVSYEPFRLGLTFREAPEEARPDNYMVSNGTNMLLVICATPIKSSYKVPDEILSQKSPKFAIRHTATGIISHVDSAAVSALGYLPQDLIGRSIMDFYHHEDLSVMKETYETVMKKGQTAGASFCSKPYRFLIQNGCYVLLETEWTSFVNPWSRKLEFVVGHHRVFQGPKQCNVFEAAPTCKLKISEEAQSRNTRIKEDIVKRLAETVSRPSDTVKQEVSRRCQALASFMETLMDEVSRADLKSGSSGNFTTASNIHMSSVTNTSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGNGTNSGTGTGTTSSSRGGSTAIP
What is the function of this protein?
Essential for biological clock functions.  Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms.  Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system.  The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex.  Light induces the degradation of TIM, which promotes elimination of PER.  Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop.  Behaves as a negative element in circadian transcriptional loop.  Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).
What are the official names of this protein?
Period circadian protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Nuclear at specific periods of the day. First accumulates in the perinuclear region about one hour before translocation into the nucleus. Interaction with Tim is required for nuclear localization (By similarity).
Protein: UXAC_ECOK1
Sequence: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: CYC6_NEOYE
Sequence: MKKKLSVLFTVFSFFVIGFAQIAFAADLDNGEKVFSANCAACHAGGNNAIMPDKTLKKDVLEANSMNTIDAITYQVQNGKNAMPAFGGRLVDEDIEDAANYVLSQSEKGW
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: OFT30_ARATH
Sequence: MNNFFNPSRPSPRPWPNRKKQTDKSAIFLCSVSILVVFFIVVFFITYSEMPKSLFSISAFSGSVQFPQCRSEILTRTLLGQKFLWYAPHSGFSNQLSEFKNALLMAGILNRTLIIPPILDHHAVALGSCPKFRVLSPSEIRISVWNHSIELLKTDRYVSMADIVDISSLVSSSAVRVIDFRYFASLQCGVDLETLCTDDLAEQSQAYESLKQCGYLLSGVRGNVDKCLYAVDEDCRTTVWTYKNGEADGRLDSFQPDEKLKKKKKLSNVRRRRDVYKTLGHGTEAESAAILAFGSLFTAPYKGSELYIDIHKSPKIKSLVEKVDFLPFVREIMIAGKKFASETIKAPFLCAQLRLLDGQFKNHRESTFTGLYQKLEALSVKNPGLINVFVMTDLPEFNWTGTYLGDLSKNSTNFKLHFIGEQDEFLARTEHELDSASHGQKFGSIPMSLDSIKKMQTHCYPHGGSNVQLYIEEAVCSCASLGFVGTPGSTIADSVEMMRKYNACSSS
What are the official names of this protein?
O-fucosyltransferase 30, O-FucT-30, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: AZOR_YERE8
Sequence: MSKVLVLKSSILATYSQSNQLADFFVEQWKTAHAGDEITVRDLAAQPIPVLDGELVGALRPSDAALTPRQQEALALSDELIAELQANDVIVMAAPMYNFNIPTQLKNYFDLIARAGVTFRYTEKGPEGLITGKRAIILTSRGGIHKDTPTDLVVPYLRLFLGFIGITDVKFVFAEGIAYGPEVATKAQADAKELLTQVVSA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: FHDC1_HUMAN
Sequence: MHVMNCVSLVSDKENGNIATAPGFMIGQTPPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPIPPPPPGLPPTTHMNGYSHLGKKKRMRSFFWKTIPEEQVRGKTNIWTLAARQEHHYQIDTKTIEELFGQQEDTTKSSLPRRGRTLNSSFREAREEITILDAKRSMNIGIFLKQFKKSPRSIVEDIHQGKSEHYGSETLREFLKFLPESEEVKKLKAFSGDVSKLSLADSFLYGLIQVPNYSLRIEAMVLKKEFLPSCSSLYTDITVLRTAIKELMSCEELHSILHLVLQAGNIMNAGGYAGNAVGFKLSSLLKLADTKANKPGMNLLHFVAQEAQKKDTILLNFSEKLHHVQKTARLSLENTEAELHLLFVRTKSLKENIQRDGELCQQMEDFLQFAIEKLRELECWKQELQDEAYTLIDFFCEDKKTMKLDECFQIFRDFCTKFNKAVKDNHDREAQELRQLQRLKEQEQKQRSWATGELGAFGRSSSENDVELLTKKGAEGLLPFLHPRPISPSSPSYRPPNTRRSRLSLGPSADRELLTFLESSTGSPEEPNKFHSLPRSSPRQARPTIACLEPAEVRHQDSSFAHKPQASGGQEEAPNPPSAQAHQLAAAQPENHASAFPRARRQGVSVLRKRYSEPVSLGSAQSPPLSPLALGIKEHELVTGLAQFNLQGSQGMEETSQLTLSDFSPMELESVGHRGPQSLSASSSSLTPMGRDALGSLSPALEDGKAAPDEPGSAALGSVGSSDPENKDPRPLFCISDTTDCSLTLDCSEGTDSRPRGGDPEEGGEGDGSMSSGVGEMGDSQVSSNPTSSPPGEAPAPVSVDSEPSCKGGLPRDKPTKRKDVVAPKRGSLKEASPGASKPGSARRSQGAVAKSVRTLTASENESMRKVMPITKSSRGAGWRRPELSSRGPSQNPPSSTDTVWSRQNSVRRASTGAEEQRLPRGSSGSSSTRPGRDVPLQPRGSFKKPSAKPLRNLPRQKPEENKTCRAHSEGPESPKEEPKTPSVPSVPHELPRVPSFARNTVASSSRSMRTDLPPVAKAPGITRTVSQRQLRVKGDPEDAAPKDSSTLRRASSARAPKKRPESAEGPSANTEAPLKARGAGERASLRRKDSSRTTLGRILNPLRK
What is the function of this protein?
Microtubule-associated formin which regulates both actin and microtubule dynamics.  Induces microtubule acetylation and stabilization and actin stress fiber formation (PubMed:18815276).  Regulates Golgi ribbon formation (PubMed:26564798).  Required for normal cilia assembly.  Early in cilia assembly, may assist in the maturation and positioning of the centrosome/basal body, and once cilia assembly has initiated, may also promote cilia elongation by inhibiting disassembly (PubMed:29742020).
What are the official names of this protein?
FH2 domain-containing protein 1, Inverted formin-1.
What are the subcellular locations of this protein?
Cell projection, cilium. Golgi apparatus. Note=Associates with microtubules.
Protein: CSLC9_ORYSJ
Sequence: MAPWSGLWGGKLAAGESPVLRSRFYAFIRAFVVLSVLLLIVELGAYINGWDDLAASALALPVIGVESLYASWLRFRATYVAPFIQFLTDACVVLFLIQSADRLIQCLGCFYIHLKRIKPNPKSPALPDAEDPDAAYYPMVLVQIPMCNEKEVYQQSIAAVCNLDWPRSNFLVQVLDDSDDPTTQTLIREEVLKWQQNGARIVYRHRVLRDGYKAGNLKSAMSCSYVKDYEFVAIFDADFQPNPDFLKRTVPHFKDNDELGLVQARWSFVNKDENLLTRLQNINLCFHFEVEQQVNGIFLNFFGFNGTAGVWRIKALDDSGGWMERTTVEDMDIAVRAHLRGWKFIFLNDVECQCELPESYEAYRKQQHRWHSGPMQLFRLCLPDIIKCKIVFWKKANLIFLFFLLRKLILPFYSFTLFCIILPMTMFVPEAELPDWVVCYIPALMSLLNILPSPKSFPFIIPYLLFENTMSVTKFNAMISGLFQLGNAYEWVVTKKSGRSSEGDLISLAPKELKHQKTESAPNLDAIAKEQSAPRKDVKKKHNRIYKKELALSLLLLTAAARSLLSKQGIHFYFLLFQGISFLLVGLDLIGEQIE
What is the function of this protein?
Probable beta-1,4-glucan synthase rather involved in the synthesis of the xyloglucan backbone than cellulose.  Seems to work simultaneously with xyloglucan 6-xylosyltransferase.  Xyloglucan is a noncellulosic polysaccharides of plant cell wall and consists of a glucan backbone substituted by xylose, galactose and fucose (By similarity).
What are the official names of this protein?
Probable xyloglucan glycosyltransferase 9, Cellulose synthase-like protein C9, OsCslC9.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: SRY_CANLF
Sequence: MFRALNCDDHGAAVQQNAFGFPRKSSDRWTDNSTSNYRCESGGNGRDSGRNRVRRPMNAFLVWSRDQRRKMALENPQMQNSEISKQLGYQWKMLTEAEKWPFFEEAQRLQAMHREKYPDYKYRPRRKATAQKSHKLLPAASSSMLCKQVHVDERFYPFTYTDSCSRAAHTRMEDQLSCSQPMSTARSLLQQEYHSSSASLRDSPETLAAQMSADASFYSK
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: CJ053_XENTR
Sequence: MPEKALVTLRFGPYSSSSGLVDHRVSRLQGLRAVLVSDGHQVILEEILDRNTVELIVNGELVFRCNIKELDFGGDGQLDPLCEEARKAVKDAY
What are the official names of this protein?
UPF0728 protein C10orf53 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0728 family.
Protein: NR_NARAP
Sequence: MSLEKRWSLEGTTALVTGGTKGIGHAIVEELVGFGARVYTCSRNEAELRKCLQEWENLKYDVTGSVCDVSSRTEREKLAEEVSSVFNGKLNILINNAGGYVNKPIDGFTAEDFSFLVAVNLESAFHLCQLAHPMLKASGTGSIVHISSCCAQIAIPGHSIYSSTKGAINQLTRNLACEWAKDNIRTNSIAPGAIRTPGTESFVIDKDALDREVSRVPFGRIGEPEEVASLAAFLCMPSASYITGQVICVDGGRTING
What is the function of this protein?
In the Amaryllidaceae alkaloids biosynthesic pathway, catalyzes the conversion of noroxomaritidine to oxomaritidine, a precursor of haemanthamine- and crinamine-type alkaloids, promising anticancer agents (PubMed:27252378).  Can also, to some extent, catalyze the condensation of 3,4-dihydroxybenzaldehyde (3,4-DHBA) and tyramine to produce norbelladine, and of isovanillin and tyramine to produce 4'-O-methylnorbelladine (PubMed:27252378).
What are the official names of this protein?
Noroxomaritidine/norcraugsodine reductase, NorRed.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily.
Protein: CTAA_STAA2
Sequence: MFGKKNLKWLGVVATLMMTFVQLGGALVTKTGSADGCGSSWPLCHGALIPEFFPIDTIIELSHRAVSALSLLMVLWLVITAWKHIGYIKEIKPLSIISVGFLLLQALIGAAAVIWQQNDYVLALHFGISLISFSSVFLITLIIFSIDQKYEADELYIKKPLRRLTWLMAIIIYCGVYTGALVRHADASLAYGGWPLPFHDLVPHSEQDWVQLTHRIMAFIVFTIIMITYIHAVKNYPNNRTVHYGYTAAFILVILQVITGALSIMTNVNLIIALFHALFITYLFGMTTYFIMLMLRSVRSDKQ
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL333_STRT2
Sequence: MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVIFTEVK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NAGB_SALG2
Sequence: MRLIPLSTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPLTAYKALVEMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYHSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDGDVNQVPKYALTVGVGTLLDAEEVMILVLGHQKAQALQAAVEGNVNHMWTISCLQLHPKAVVVCDEPSTMELKVKTLKYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: FETP_TOLAT
Sequence: MTRMVFCQRLKKEAPGMAFQLVPGELGKRIFDNICQEAWAEWQKKQTMLINEKKLNMMNAEHRALLQTEMEKYLFEDGDVQIEGYVPPSEK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: U1148_ARATH
Sequence: MDRPPSLPHYQNPNPNLFYHYPPPNSNPNFFFRPPPPPLQNPNNYSIVPSPPPIRELSGTLSSLKSLLSECQRTLDSLSQNLALDHSSLLQKDENGCFVRCPFDSNHFMPPEALFLHSLRCPNTLDLIHLLESFSSYRNTLELPCELQLNNGDGDLCISLDDLADFGSNFFYRDCPGAVKFSELDGKKRTLTLPHVLSVECSDFVGSDEKVKKIVLDKCLGVLPSDLCAMKNEIDQWRDFPSSYSSSVLSSIVGSKVVEISALRKWILVNSTRYGVIIDTFMRDHIFLLFRLCLKSAVKEACGFRMESDATDVGEQKIMSCKSSTFECPVFIQVLSWLASQLAVLYGEGNGKFFALDMFKQCIVESASQVMLFRLEGTRSKCSGVVEDLDDARLRNKDVIMEKPFENSSGGECGKTLDSPQVISVSRVSAAVAALYERSLLEEKIRAVRYAQPLTRYQRAAELGFMTAKADEERNRRCSYRPIIDHDGRPRQRSLNQDMDKMKTREELLAEERDYKRRRMSYRGKKVKRTPRQVLHDMIEEYTEEIKLAGGIGCFEKGMPLQSRSPIGNDQKESDFGYSIPSTDKQWKGENRADIEYPIDNRQNSDKVKRHDEYDSGSSQRQQSHRSYKHSDRRDDKLRDRRKDKHNDRRDDEFTRTKRHSIEGESYQNYRSSREKSSSDYKTKRDDPYDRRSQQPRNQNLFEDRYIPTEKE
What is the function of this protein?
Likely involved in U12-type 5' splice site recognition.
What are the official names of this protein?
U11/U12 small nuclear ribonucleoprotein 48 kDa protein, U11/U12 snRNP 48 kDa protein, U11/U12-48K.
What are the subcellular locations of this protein?
Nucleus.
Protein: VIRE2_AGRFC
Sequence: MDPKAEGNGENITETAAGNVETSDFVNLKRQKREGVNSTGMSEIDMTGSQETPEHNMHGSPTHTDDLGPRLDADMLDSQSSHVSSSAQGNRSEVENELSNLFAKMALPGHDRRTDEYILVRQTGQDKFAGTTKCNLDHLPTKAEFNASCRLYRDGVGNYYPPPLAFERIDIPEQLAAQLHNLEPREQSKQCFQYKLEVWNRAHAEMGITGTDIFYQTDKNIKLDRNYKLRPEDRYIQTEKYGRREIQKRYEHQFQAGSLLPDILIKTPQNDIHFSYRFAGDAYANKRFEEFERAIKTKYGSDTEIKLKSKSGIMHDSKYLESWERGSADIRFAEFAGENRAHNKQFPAATVNMGRQPDGQGGMTRDRHVSVDYLLQNLPNSPWTQALKEGKLWDRVQVLARDGNRYMSPSRLEYSDPEHFTQLMDQVGLPVSMGRQSHANSVKFEQFDRQAAVIVADGPNLREVPDLSPEKLQQLSQKDVLIADRNEKGQRTGTYTNVVEYERLMMKLPSDAAQLLAEPSDRYSRAFVRPEPALPPISDSRRTYESRPRGPTVNSL
What is the function of this protein?
Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element.  Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence composition.
What are the official names of this protein?
Single-strand DNA-binding protein, 63.5 kDa virulence protein.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=In infected cells, it is found in the nucleus.
Protein: MIAB_HYDCU
Sequence: MSELQSRTSPFSGGLFIKTYGCQMNEYDSDRMAKLLEKTYGLNLVETPEEADMLLLNTCSVREKAQEKVFDELGRWKKWKAAKPNRVIGVGGCVASQEGDVIRKRAPLVDVIFGPQTLHRLPAMIEEALALRTATEQDKKLKKRAIIDISFPEIEKFDNLAEPESNGVSAFVSVMEGCSKYCTFCVVPYTRGEEFSRPFSDVMAEIESLAKQGVREVNLLGQNVNAYRGEMPDGEMADLAVLIHAVRAVEGIDRIRFTTSHPNEMTQSLIDCYAEVPELVSHLHLPIQSGSDRVLAMMKRNHMAIEYKATIRKIKKIRPDLSLSGDFIIGFPGETCDDFKETLALVKEMNYDRSFSFIYSPRPGTPAASLPDDVELHMKKRRLQALQAMLNEQTAAISEGMVGTTQRVLVERLSRNSTNEVSGRTENNRVVNFEGPPELIGQFVDVLIEEAYANSLKGKLVATPEAEQFNQRQFYAL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_YERPN
Sequence: MATPGFPSTEQRLGLYPVVDSLLWIERLLAAGVTTLQLRIKNADDAQVEQDIVAAIELGKRYQARLFINDYWQLAVKHGAYGVHLGQEDLEAADLAAIQQAGLRLGISTHDEHELAVAKTLRPSYIALGHIFPTQTKQMPSSPQGLASLSRQVKNTPDYPTVAIGGISIERVPHVLATGVGSVAVVSAITLASDWQRATAQLLHLIEGKELADEK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.