PharMolix/UniProtQA huggingface dataset:
Protein: NPHN_MOUSE
Sequence: MGAKEATVRGPGASPVHRTCHLIPLLLAGMLTTGLAQSPVPTSAPRGFWALSENLTVVEGSTVKLWCGVRAPGSVVQWAKDGLLLGPNPKIPGFPRYSLEGDSAKGEFHLLIEACDLSDDAEYECQVGRSELGPELVSPSVILSILVSPKVLQLTPEAGSTVTWVAGQEYVVTCVSGDAKPAPDIIFIQGGRTVEDVSSSVNEGSEEKLFFTEAEARVTPQSSDNGQLLVCEGSNPALATPIKASFTMNILFPPGPPVIDWPGLNEGHVRAGENLELPCIARGGNPPATLQWLKNGKPVSIAWGTEHAQAVAHSVLVMTVRPEDHGARLSCQSYNSVSAETQERSITLQVTFPPSAVTILGSTSQSENKNVTLCCLTKSSRPRVLLRWWLGGRQLLPTDETVMDGLHGGHISMSNLTLLVKREDNGLSLTCEAFSDAFSKETFKKSLTLNVKYPAQKLWIEGPPEGQSIRTGTRVRLVCLAIGGNPEPSLTWLKDSRPVNDPRQSQEPRRVQLGSVEKSGSTFSRELVLIIGPPDNLAKFSCKAGQLSASTQLVVQFPPTNLTILANSSALRPGDALNLTCVSISSNPPVNLSLDKEGERLDDVAAKPQSAPFKGSAASRSVFLRVSSRDHGHRVTCRAHSEALRETVSSFYRLNVLYPPEFLGEQVRAVTVVEQGQALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSGGALQLWNVTRADDGFYQLHCQNSEGTAEALLKLDVHYAPTIRALKDPTEVNVGGSVDIVCTVDANPILPEMFSWERLGEDEEELNLDDMEKMSKGSTGRLRIRQAKLSQAGAYQCIVDNGVAPAARGLVRLVVRFAPQVDHPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDPRYTEHKYHQGVVHSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSVSPHSVGLEWKPGFDGGLPQRFQIRYEALESPGFLYMDVLPAQATTFTLTGLKPSTRYRIWLLASNALGDSGLTDKGIQVSITTPGLDQAPEDTDQPLPTEQPPGPPRLPLLPVLFAVGGLLLLSNASCVGGLLWRRRLRRLAEEISEKTEAGSEEDRIRNEYEESQWTGDRDTRSSTVSTAEVDPHYYSMRDFSPQLPPTLEEVSYRQAFTGIEDEDMAFPGHLYDEVERVYGPPGVWGPLYDEVQMDPYDLRWPEVKYEDPRGIYDQVAADMDAGEPGSLPFELRGHLV
What is the function of this protein?
Seems to play a role in the development or function of the kidney glomerular filtration barrier.  Regulates glomerular vascular permeability.  May anchor the podocyte slit diaphragm to the actin cytoskeleton.  Plays a role in skeletal muscle formation through regulation of myoblast fusion.
What are the official names of this protein?
Nephrin, Renal glomerulus-specific cell adhesion receptor.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Located at podocyte slit diaphragm between podocyte foot processes.
Protein: DJC17_BOVIN
Sequence: MAVTKELLQMDLYALLGIEEKAEDKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVRKAKKQAAERTQKLDERRKKVKLDLEARERQAQALGSEEEEESGSARTLEQEIERLREEGSRQLEEQQRLIREQIRQEQEQRLTGMAKNPENKETPKLKLKWKSKKEAESQGGYSRDVLLQLFQKYGEVLNLVLSSKKAGTAVVEFATVKAAELAVQNEVGLVDNPLKISWLEGRPQSAMGHNHPGLSRGSVVSERDYESLVMMRMRQAAERQQLIAQMQQEDQAGQPT
What is the function of this protein?
May negatively affect PAX8-induced thyroglobulin/TG transcription.
What are the official names of this protein?
DnaJ homolog subfamily C member 17.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly nuclear.
Protein: NIFSL_ASFP4
Sequence: MASILTLDGLYAEVPKFLPEALREGCAGKNPLSFYIQQILNLMGCDGNEYHVLFTSSSEEANTHMIMAAVRRHLLRTQQRPHVIIGAGEPPSITECVKALAQEKRCVYTIIPLKNFEIDPVAVYDAIQSNTCLACISGTNAVVKTFNKLQDISKVLRGIPLHSEVSDLVYQGCIKQNPPADSFSINSLYGFLGVGILGMKKKVMQGLGPLIFGGGLRGGSPNIPGIHAMYRTLTQQRPSIKKINTIHKLFMKTLKKHQHVYLPIGGVSAEDMSTKDMSTKDIPSTDMLVGPKGLPGYILFSVGHRAEELQKKIFTKFNIKIGRIVDLQEILFRIKIPQKYWETLLFIQLRDNLTKEDIKRVMVVLMHLDTITPRGSLPPPSYSSSFS
What are the official names of this protein?
NifS-like protein.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Virion.
Protein: RPOZ_OLEA2
Sequence: MARITVEDCMERVSNRFLLVQMAIKRVKQFREGYEPLVPSKNKEIVTALREIAAAKVVPEDELSAAAAENRAE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ENO_SHEPW
Sequence: MAKIINIIGREIMDSRGNPTVEAEVHLEGGFMGMAAAPSGASTGSREALELRDGDKARYLGKGVLKAVEAVNGTIADALIGKDATAQAELDQIMIDLDGTENKAKFGANAILAVSLAAAKAAAAFKGVPLYAHIADLNGTPGVYSMPLPMMNIINGGEHADNSVDIQEFMIQPVGAANFREGLRMGAEVFHSLAKVLKADGHSTAVGDEGGFAPNLPSNASALAAIKVAVANAGYELGKDITLAMDCAASEFYDKEANIYDLKGEGKKFTSEEFNFFLQDLTKEYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDRVAKYNQLLRIEEQLGEKAPYKGLKEVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RH51_ARATH
Sequence: MVESDKSSVEELKKRVRKRSRGKKNEQQKAEEKTHTVEENADETQKKSEKKVKKVRGKIEEEEEKVEAMEDGEDEKNIVIVGKGIMTNVTFDSLDLSEQTSIAIKEMGFQYMTQIQAGSIQPLLEGKDVLGAARTGSGKTLAFLIPAVELLFKERFSPRNGTGVIVICPTRELAIQTKNVAEELLKHHSQTVSMVIGGNNRRSEAQRIASGSNLVIATPGRLLDHLQNTKAFIYKHLKCLVIDEADRILEENFEEDMNKILKILPKTRQTALFSATQTSKVKDLARVSLTSPVHVDVDDGRRKVTNEGLEQGYCVVPSKQRLILLISFLKKNLNKKIMVFFSTCKSVQFHTEIMKISDVDVSDIHGGMDQNRRTKTFFDFMKAKKGILLCTDVAARGLDIPSVDWIIQYDPPDKPTEYIHRVGRTARGEGAKGKALLVLIPEELQFIRYLKAAKVPVKELEFNEKRLSNVQSALEKCVAKDYNLNKLAKDAYRAYLSAYNSHSLKDIFNVHRLDLLAVAESFCFSSPPKVNLNIESGAGKVRKARKQQGRNGFSPYSPYGKSTPTKEA
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 51.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
Protein: KEFB_ESCF3
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CA1_CONGE
Sequence: MGMRMMFTVFLLVVLATTVVSFPSERASDGRDDTAKDEGSDMDKLVEKKECCNPACGRHYSCGR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (PubMed:9174364, PubMed:30551685, PubMed:34062129, PubMed:35357806).  Reversibly inhibits mammalian muscle nAChR (IC(50)=339 nM on adult subtype (alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND) and IC(50)=5. 86-995 nM on fetal subtype (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE)) (PubMed:30551685, PubMed:34062129, PubMed:35357806).  The higher affinity site is the alpha/delta site on mouse muscle-derived BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from Torpedo californica electric organ (PubMed:7623764).
What are the official names of this protein?
Alpha-conotoxin GI, G1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DAVD_PSEPK
Sequence: MQLKDAQLFRQQAYINGEWLDADNGQTIKVTNPATGEVIGTVPKMGTAETRRAIEAADKALPAWRALTAKERSAKLRRWFELMIENQDDLARLMTTEQGKPLAEAKGEIAYAASFIEWFAEEAKRIYGDTIPGHQPDKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPYSALALVELAHRAGIPAGVLSVVTGSAGEVGGELTGNSLVRKLSFTGSTEIGRQLMEECAKDIKKVSLELGGNAPFIVFDDADLDKAVEGAIISKYRNNGQTCVCANRIYVQDGVYDAFAEKLAAAVAKLKIGNGLEEGTTTGPLIDGKAVAKVQEHIEDAVSKGAKVLSGGKLIEGNFFEPTILVDVPKTAAVAKEETFGPLAPLFRFKDEAEVIAMSNDTEFGLASYFYARDMSRVFRVAEALEYGMVGINTGLISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYLCISV
What is the function of this protein?
Catalyzes the conversion of 5-oxopentanoate (glutarate semialdehyde) to glutarate.  Involved in L-lysine degradation.
What are the official names of this protein?
Glutarate-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: RS2_HAEIE
Sequence: MAQVSMRDMINAGVHFGHQTRYWNPQMKPFIFGARNGVHIINLEKTLPLFNEALAELTRIASNNGKVLFVGTKRAASEAVQAAALDCQQYYVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRSREMEKLELSLGGIKDMGGLPDALFVIGADHEHIAVKEANNLGIPVFAIVDTNSTPAGVDFVIPGNDDATRAIQLYVSAAAAAVKEGRGNEAQVAEELAADAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CDKL2_MOUSE
Sequence: MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRLPEVKDAEAEPLESRYPKLPEAVISLAKKCLHIDPDKRPFCADLLRHDFFQMDGFAERFSQELQLKIEKDARNNSLPKKSQNRKKEKDDALGEERKTLVVQDTNADPKIKDSKVFKVKGSKIDVEKMEKGSRASNANCLHDNGTNHKGLASTSLRDCSNVNIDHSRNPGTAIPPLTHNLSAVAPGINAGMGTIPGVQNYRVDEKTKKYCNPFVKPNQPPPAGIYNMNVSTSVSGEKYLLQANKKRKEYPKADVRLPELNYNHLPELRALEGIARNSRLIKKENKCLSESRIPSLAAIDLHVSSVASHQGAGSPLSDDSEADLPRMEHQH
What are the official names of this protein?
Cyclin-dependent kinase-like 2, Serine/threonine-protein kinase KKIAMRE.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: QUEC_BACFN
Sequence: MKNDSAVVLFSGGQDSTTCLFWAKKHFKKVYALSFLYGQKHAHEVELARGIAERAGVEFHVMDTSFIGSLGSNSLTDTSISMDEDKPKDSFPNTFVPGRNLFFLSIAAVFAREQGAFHLVTGVSQTDYSGYPDCRDSFIKSLNVTLNLAMDEQFVIHTPLMWIDKAETWALADELGVFDLVRNETLTCYNGIPADGCGHCPACKLRKQGLEEYLSKRNR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: CLCA_SALPA
Sequence: MKTDTSTFLAQQIVRLRRRDQIRRLMQRDKTPLAILFMAAVVGTLTGLVGVAFEKTVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGCVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGFNLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHPEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQAAKNQNAPAGENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HUTH_SALSV
Sequence: MNTITLTPGQLSLSQLYDVWRHPVQLRLDASAIDGINASVACVNDIVAEGRTAYGINTGFGLLAQTRIADEDLQNLQRSLVLSHAAGVGDPLDDAMVRLIMVLKINSLARGFSGIRLSVIEALIALVNAGVYPLIPAKGSVGASGDLAPLAHLSLTLLGEGKARWQGEWLPAQTALKKAGLEPVALAAKEGLALLNGTQASTAFALRGLFEAQELFASAVVCGALTTEAVLGSRRPFDARIHAARGQQGQIDVARLFRHLLTDTSAIAESHHHCHKVQDPYSLRCQPQVMGACLTQLRQTKEVLLAEANAVSDNPLVFADAGEVISGGNFHAEPVAMAADNLALAIAEIGALSERRIALMMDKHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALAHPHSVDSLPTSANQEDHVSMAPAAGRRLWEMAANTRGIIAVEWLAACQGIDLREGLTSSPLLEQARQTLRERVAHYTQDRFFAPDIECATALLAQGALQRLVPDFM
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_THEP1
Sequence: MWIDCRTIARSIEERTKERVEKLGFTPKLVSVACTDDPSTLSYLKSQRKKAEKLGIAFEILNVSPEEIVSTLKKLGSDESVNGVFVARPFPPSFDEKEILSSVPVEKDVEGVNPANLGLLLYDEEIFPPCTAEAAVRILERETNLSGKRVTVVGRSVTVGKPLALMLLKKGRDATVTVCHSRTVNLEEITKNSDIVVVAVGRAHFLKKNMVKEGAIVIDVGINYVDGKLQGDVDPSVEEIARVTPVPGGVGQVTTALLFEHVVRAAERQRK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SYM_HAEIE
Sequence: MTTQPRKILVTCALPYANGAIHLGHMLEHIQADIWVRFQRMRGNKIHFVCADDAHGTPIMLNADKLGITPEELIAKAKADHMRDFAGFNISFDNYHSTHSEENKQLTAEIYNKLKANGFIKSKVISQLFDPEKNMFLPDRFVKGTCPKCKAEDQYGDNCEVCASTYSPMDLINPRSAVSGTTPIVKESEHFFFDLPAFEGMLKEWTRSGSLQSEIANKMQEWFESGLQQWDISRDTPYFGFEIPGVKDKFFYVWLDAPIGYMASFKNLCNREGIDFNEFWAEGSDAELYHFIGKDIVYFHSLFWPAMLEGSGYRKPTNVFAHGYVTVDGAKMSKSRGTFIQASTYLNHIDPECLRYYYAAKLNDRIEDLDFNLEDFVQRVNTDIVNKLVNLASRNAGFIAKRFEGKLADKLEDEALFAEFTAQAEQIAAYYESREYNKAIREIMALTDKANKYIDEKAPWVIAKEEGKEAELQAVCSMGIELFRVLMSYLKPVLPKLAERAETFLQAELRWDNIHQPLLGHTLAPFKALFSRLEKKQIDAVVEETKALFAAANKAAEKTEAKPTALSTVEPIAETITIDDFAKLDMRVAKVLKCEAVPESNKLLRFELDLGDHTRQVFSSIKAAYNKPEELEGRFVIMVANLAPRKMKFGVSEGMILSAGTGGSDLFLLSADSGVTAGMQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_LEGPL
Sequence: MILCIDVGNSHIYGGVFDGDEIKLRFRHTSKVSTSDELGIFLKSVLRENNCSPETIRKIAICSVVPQVDYSLRSACVKYFSIDPFLLQAGVKTGLNIKYRNPVEVGADRIANAIAATHSFPNQNIIVIDFGTATTFCAISHKKAYLGGAILPGLRLSADALSKNTAKLPSVEIIKTESVVGRSTIESIQSGVYYGVLGACKELIQRIHHEAFNGDKILILATGGFASLFDKQGLYDHLVPDLVLQGIRLAAMMNTA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_CAUVN
Sequence: MDRIAIIGGAQLNGTIPVSGAKNSAIKLMAASLLTDEPLRLTNMPRLADTRFLGKLLTRLGVQVTESDGSDGQQTLLHAPEITSGFAPYDLVRQMRASFNVLGPLVARSGQAKVSLPGGCTIGARPVDLHLQAIEALGAKIDLHEGYVYAQAPRGLKGAEIRFPFVSVGATEHAMLAAVLADGVSVIHNAACEPELVDLQECLNAMGAKVEGAGTPTVTITGVPRLHGATHAVIPDRIEMGTYAVAAAMAGGEVRLSNARPGLIDALLDKLKEAGASVEETADGCIIRRNGQRLTAVDIETAPFPGFATDLQAQFMALMTTAKGESRIRETIFENRFMHAPELMRLGADISVSGGEARVRGVDQLEGAQVMATDLRASVSLVIAGLVARGETTVSRIYHLDRGFERLEEKLGACGAQVRRIKGDGEAEL
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTNA1_CHICK
Sequence: MSLVMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSLRDTYLQQKWQQVWQEISVEAKHVKDIMKMLESFKIDSTPPKASQQELPAHDAEVWSLPVPAERRPSPGPRKRQSAQYSDCRGHNNRISAAVRGPHRPSSRNPNDKGKAVRGREKKDQQNKGKEEKSKSTSEISESEPKKFDSTGYDKDLVEALERDIISQNPNIRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGATENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGREELLRINLRELELADDVDLANIAEKMEGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNLSRDEMHMPTTMEDFEIALKKVSKSVSAADIEKYEKWIVEFGSC
What is the function of this protein?
Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner.  Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, p60 katanin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Predominantly cytoplasmic. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with KATNB1.
Protein: RL32_DROYA
Sequence: MTIRPAYRPKIVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHGVSSKKRKEIVERAKQLSVRLTNPNGRLRSQENE
What are the official names of this protein?
60S ribosomal protein L32, Ribosomal protein 49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: GNPAT_MOUSE
Sequence: MDVPSSSSSRFSVGSASPSSVLLYAKDLKKWDEFEDLLEERRHISDFKFAMKCYTPPLYRGITPCKPGDIKSIVLSSEEINYVIKQLSRESLTGVDVLREEASEILEEMSHKLRIGAIRFFAFVLSKIFKQIFSKVCVNEEGIQKLQRAVQEHPVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRCGYAPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSLAAGRLNRNTYNLVPRCIPQKQPEDVQAFVTEVAYKMQLLQIENLALSPWLLVVTILLQNQLSMDFDALVEKTLWLKGVTQVFGGFLLWPDNKLPEEVVQSSILLHSNLASLVKDQVVLKMNSGSSQVVNGLVPEHIALLMCSAYRNQLLNIFARPSLVALALHMTPGLRKEDVFSCFSFLRNVFSDEFIFLPGNTLRDFEEGCYLLCKAEAMQMAGKDIILTDKGTAVLQFLTSLFKPFVESYQLLCRYLLHEEDYFGEKEYLVAARKFTRQLLDQGSSQCYDALSSELQKNALAAFVRLGVVEKKKVDSKYVYYVNGPATSKLEEMLGCKKPIGKPATAKL
What is the function of this protein?
Dihydroxyacetonephosphate acyltransferase involved in plasmalogen biosynthesis.
What are the official names of this protein?
Dihydroxyacetone phosphate acyltransferase, DAP-AT, DHAP-AT, Acyl-CoA:dihydroxyacetonephosphateacyltransferase, Glycerone-phosphate O-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Peroxisome membrane; Peripheral membrane protein; Matrix side. Note=Exclusively localized to the lumenal side of the peroxisomal membrane.
Protein: SHO1_USTMA
Sequence: MPSKRGGSGGLDIGLIFAHKILTVLFILSTVGWIVAFIGQCAAEADGVGRQGVLWFAIFLQLFLIIGKYLGVMSDSLGTSRLQLTAFTAVALVFSVFGINSGIYSSNSADEAVAAGWFLITIANVIWLLFLTTEEDSVLYPIVNIANAGITPPAARTSSRYNGAGGAGSGGQSMRMAGSGGVGTGLGGGYGAGNGSAYGGFQGGSGYQPAYGNSPSAADITTANGTGLGAPKISSASIRSRGANDAGATQDAPSVASHGAPASPAQVGSKSTDLPDYGYKARALYAYQANADDPTEISFSKGEVLDIVDNSGKWWQARRSNGETGIVPSNYMQLL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_CRANE
Sequence: MTIMRKSHPLMKIVNHAFIDLPTPPNISGWWNFGSLLGLCLVLQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYMHANGASLFFICLYIHIGRGIYYGSYLYTETWNIGILLLFLTMATAFVGYVLPWGQMSFWGATVITNLLSAIPFIGQDLVEWIWGGFSVDKSTLTRFFAFHFILPFIITALAMVHLLFLHETGSNNPLGIPSDCGKVPFHPYYTTKDLLGAILLLMLFMTLVLFFPDKLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVCALVFSILVLALLPYLHTSKQRSLSFRPLSQTMFWALVSDLIILTWIGGQPVEPPYIIIGQVASILYFSIILILMPMAGLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS9_SHEAM
Sequence: MAATQYYGTGRRKTSTARVFAKVGSGNIIVNKRPLDVYFGRETARMVVRQPLELVEMTEKLDIYVTVKGGGITGQAGAIRHGITRALMELDESLRPTLRAAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: Y429_STRR6
Sequence: MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINGVFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAIAGTLLLLAYAGTQTRAGSLKKD
What are the official names of this protein?
UPF0397 protein spr0429.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CMOA_ECO5E
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHKAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: M1_I000X
Sequence: MSFLTEVETYVLSIIPSGPLKAEIAQRLEDVFAGKNTDLEVLMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEISLSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMITIGTHPSSSAGLKNDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.