PharMolix/UniProtQA huggingface dataset:
Protein: BMCT2_HALO1
Sequence: MSITLRTYIFLDALQPQLATFIGKTARGFLPVPGQASLWVEIAPGIAINRVTDAALKATKVQPAVQVVERAYGLLEVHHFDQGEVLAAGSTILDKLEVREEGRLKPQVMTHQIIRAVEAYQTQIINRNSQGMMILPGESLFILETQPAGYAVLAANEAEKAANVHLVNVTPYGAFGRLYLAGSEAEIDAAAEAAEAAIRSVSGVAQESFRDR
What is the function of this protein?
A minor component of the bacterial microcompartment (BMC) shell.  Expression of 5 proteins in E. coli (BMC-H (Hoch_5815), BMC-P (Hoch_5814), and 3 BMC-T (Hoch_5812, Hoch_5816, Hoch_3341)) forms 40 nm artificial BMCs with a molecular mass of 6. 5 MDa.  One of 2 stacked pseudohexamers in the BMC.  There are 20 BMC-T pseudohexamers per BMC, composed of mixed BMC-T1, BMC-T2 and BMC-T3.  The shell facets are 20-30 Angstroms thick, with 1 of the stacked BMC-T trimers protruding to the exterior (PubMed:28642439, PubMed:30833088).  The stacked trimers may serve as conduits to allow chemical flux across the protein shell, gated by Arg-70 which contacts Glu-69 in an adjacent subunit; they are flexible enough to play a role in accommodating variations in shell assembly (Probable).
What are the official names of this protein?
Bacterial microcompartment protein trimer-2, BMC-T2, BMC-T2(D).
What is the protein family that this protein belongs to?
Belongs to the EutL/PduB family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: MTF1B_MOUSE
Sequence: MASRNIWCVRRNFLFDLRGWMLQYSAEVFLKSISFRTFSVECDSKDKESLEEEREDLLSNLVTMGVDIDMARRRQPGVFNKAVTNEQELKIFLLSKGASDKVIGSIISRYPRAITRTPESLSKRWDLWRKIMASDLEIVNILERSPESFFRSNNNLNLENNIKFLCSVGLTHKCLCRLLTNAPRTFSNSLNLNKQMVEFLQETGMSLGHNDPRDFVRKIISKNPSILIQSTKRVKTNIEFLQSTFNLNKQDLLLLICGPGARILDLSNDCTKKNYTNIRERLLSLGCSEEEVQRFVLSYLNMVFLSEKKFNDKIDCLIEEKISASQIIENPRILDSSINTLKTRIRELSHAGYDLSTSSIALLSWSQRRYEAKLKRLCG
What is the function of this protein?
Transcription termination factor.  Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination.  Binds DNA along the major grove and promotes DNA bending and partial unwinding.  Promotes base flipping.  Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.
What are the official names of this protein?
Transcription termination factor 1b, mitochondrial, Mitochondrial transcription termination factor 1b, mTERF1b.
What is the protein family that this protein belongs to?
Belongs to the mTERF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACCA_CHLMU
Sequence: MELLPHEKQVVEYEKTIADFKEKNKENSLLSSSEIQKLENRLDRLKEKIYSNLTPWERVQICRHPSRPRTINYIEGMCEEFVELCGDRTFRDDPAVVGGFAKIQGQRFMLIGQEKGCDTTSRMHRNFGMLCPEGFRKALRLAKMAEKFGLPIIFLVDTPGAFPGLTAEERGQGWAIATNLFELARLATPIIVVVIGEGCSGGALGMAIGDVVAMLEHSYYSVISPEGCASILWKDPKKNSDAAAMLKMHGEDLKGFAIVDAVIKEPIGGAHHNPVATYRSVQEYVLQEWLKLKDLPVEELLEKRYQKFRTIGLYETSSESSSEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPA_STAS1
Sequence: MTEQKKTTIGITGMTCAACANRIEKNLNKLDDVEANVNVTTEKATISYNPESTSADDLTKTIEKTGYGVLNETAELDVIGMTCAACSNRIEKVLNRTDGVDQATVNLTTENATISYNPSATSVDALIKKIQKIGYDAQPKKEVAEKSSQKELELRSKLVKLIISAVLAAPLLLTMLVHLFGIQIPSIFMNPWFQFILATPVQFIIGWQFYVGAYKNLRNGSANMDVLVALGTSAAYFYSLYEMVKWLFNANVMPHLYFETSAVLITLILFGKYLETRAKTQTTNALSELLNLQAKEARVLRDNKEQMIPLNDVVEGDYLIIKPGEKIPVDGKIIKGKTSIDESMLTGESMPVEKVQDDNVIGSTMNKNGSITVKATKVGKDTALASIIKVVEEAQGSKAPIQRLADVISGYFVPIVVGIAVLTFIIWIAFVQQGQFEPALVAAIAVLVIACPCALGLATPTSIMVGTGKAAENGILFKGGEHIERTHQIDTVVLDKTGTITNGKPVVTDFDGDEEALQLLASAEKGSEHPLADAIVNYAQTMNIKLLDTTDFEAVPGRGIKANISGKNLIVGNRQFMNDENVDIKDSEDIMTQFEKSGKTAMLIAINQEYRGMVAVADTVKDSTATAIKQLHDLNIKVVMLTGDNERTAQAIANEVGIDTIIAQVLPEEKAAKIKSLQTQDKTIAMVGDGVNDAPALVQADIGIAIGTGTEVAIEAADVTILGGDLLLIPKAIKASKATIRNIRQNLFWAFGYNVAGIPIAALGLLAPWIAGAAMALSSVSVVTNALRLKRMKL
What is the function of this protein?
Involved in copper export.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIE_PSEAE
Sequence: MNDPRKGADAEPTTHFGYQNVPESQKAKKVAEVFHSVAAKYDLMNDLMSGGIHRLWKRFTIELSGVRSGNRVLDIAGGTGDLTRQFSRLVGPTGEVVLADINASMLKVGRDKLLDKGVSGNVSFVQADAEKLPFPDNHFDCVTIAFGLRNVTHKDEAIRSMLRVLKPGGRLLVLEFSKPSSNLLSKAYDAYSFSLLPLMGKLVTNDSESYRYLAESIRMHPDQETLKAMMVEAGFDRVTYHNMTGGIVALHRGIKP
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PAND_XANCB
Sequence: MHLSLLKAKIHRATVTHSELNYEGSIAIDGLLLEATGIREFEQVHIWDVTNGARFSTYAIRAEEGSGIISLNGGAARHVQVGDLIIVAAFAGMSEDEAKTFKPNLVYVDAHNAISHTNHSIPTQAA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRA58_HUMAN
Sequence: MGCCGCSGGCGSGCGGCGSGCGGCGSSCCVPICCCKPVCCCVPACSCSSCGSCGGSKGGRGSCGGSKGDCGSCGGSKGGCGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPCCSQSSCCKPCSCSSGCGSSCCQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCVPICCQCKI
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 5-8, Keratin, ultra high-sulfur matrix protein B, Keratin-associated protein 5.8, UHS keratin B, UHS KerB, Ultrahigh sulfur keratin-associated protein 5.8.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 5 family.
Protein: RS16_BART1
Sequence: MALKIRLSRGGSKKRPYYHIVVADVRSPRDGRFLERVGAWDPMLPKDGPRVKLNEERIQYWLGQGAQPTDRVLRFLDAAGLKKRPARNNPHKGEPGKKAQERIAAAKQAAEDAAAAAEADSASE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ITPA_HUMAN
Sequence: MAASLVGKKIVFVTGNAKKLEEVVQILGDKFPCTLVAQKIDLPEYQGEPDEISIQKCQEAVRQVQGPVLVEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLAGFEDKSAYALCTFALSTGDPSQPVRLFRGRTSGRIVAPRGCQDFGWDPCFQPDGYEQTYAEMPKAEKNAVSHRFRALLELQEYFGSLAA
What is the function of this protein?
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase, Putative oncogene protein hlc14-06-p.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: COBD_METM7
Sequence: MTNPIYLILADFFDRYIGEPPEKIHPVVFIGKLICFFENVFKSTNSVNKTRDLLFGFLNVILVLAIVFFMTYEIEQIINSISNSYIKISIYSIILSFSIGHKSLIEFSKAPIKFIVNNDLEGAKKSVQCIVSRNTSELDKKHILSASIESASENITDSIIAPLIYAAIFGLPGAFLYRAVNTFDAMIGYKSEKYQYYGKTAAYLDDILNFIPSRIAGMLLIISAPFYGGNIKSAIYGYFNEGNKTPSPNSGYTMATLANSLNMELEKIGYYKLGKGEITIEKALNSLKAVDYSVLLFLIIYTVLLM
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Probable cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1051_GEOKA
Sequence: MAKIGVEPSLTDVQEALKERGYDVVPLRGEQDARGCDCCVITGLDANIAGIHNIVTSGPVIEASGLTAEEICQKVEEKLR
What are the official names of this protein?
UPF0180 protein GK1051.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: DEOC_ECO8A
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVMLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIO_TREPA
Sequence: MALLDISSGNVRKTIETNPLVIVDFWAPWCGSCKMLGPVLEEVESEVGSGVVIGKLNVDDDQDLAVEFNVASIPTLIVFKDGKEVDRSIGFVDKSKILTLIQKNA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: PSBZ_WHEAT
Sequence: MTIAFQLAVFALIATSSVLVISVPLVFASPDGWSNNKNVVFSGTSLWIGLVFLVAILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: APAG_SALPK
Sequence: MINSPRVCIQVQSVYIEAQSSPDDERYVFAYTVTIRNLGRAPVQLLGRYWLITNGHGRETEVQGEGVVGVQPRIAPGEEYQYTSGAVIETPLGTMQGHYEMIDENGDAFTIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: NUON_BDEBA
Sequence: MNINIGLSDVLLISPMIALFLASLLPITMKVLRGNREQHALITLGQALMGIVAAVVLLVVFGGSDKTAFNNGLIFDGVTQWMGIIALAGAGAAMVMMYENPSTTGKQFSELIFLAMSSAVGMLILVSAVDLLMVFIGLEMMSLALYLMIAMSHEEKLSKEAALKYFILGSFASAIFLYGVAFIFGSTGGTNILSFMDNAAELVQTSRLFLFGVTFVILGFCFKVSIAPFHAWTPDVYQGAPTPHTAFMATAVKTVSFAAFLRIIATKSLTGSDQLFDILQWMAVITMIVGNAAAIMQNNFKRMIAYSSVAHSGYLMVGLITAGVSDNGAFGASGVIFYLLAYGLMTIGAFAIAAMLEKSENHIVNIDDLAGFAKQRPMLALCLTVFLLSLAGIPPTLGFFGKFYMFNAAIGEGLLWLAIWGMLNSVIGVYYYLRPIVVMYMKEGNAEIAGHSLNATTVTAVVMALAIVLMGFVSGPIFSAVEKSLL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ERPA_ALIFM
Sequence: MSDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEDVNEGDMTIENDGVTLVVDPMSLQYLIGGKVDYTEGLEGSRFFIDNPNATTTCGCGASFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: ALKA_MYCTO
Sequence: MHDDFERCYRAIQSKDARFDGWFVVAVLTTGVYCRPSCPVRPPFARNVRFLPTAAAAQGEGFRACKRCRPDASPGSPEWNVRSDVVARAMRLIADGTVDRDGVSGLAAQLGYTIRQLERLLQAVVGAGPLALARAQRMQTARVLIETTNLPFGDVAFAAGFSSIRQFNDTVRLACDGTPTALRARAAARFESATASAGTVSLRLPVRAPFAFEGVFGHLAATAVPGCEEVRDGAYRRTLRLPWGNGIVSLTPAPDHVRCLLVLDDFRDLMTATARCRRLLDLDADPEAIVEALGADPDLRAVVGKAPGQRIPRTVDEAEFAVRAVLAQQVSTKAASTHAGRLVAAYGRPVHDRHGALTHTFPSIEQLAEIDPGHLAVPKARQRTINALVASLADKSLVLDAGCDWQRARGQLLALPGVGPWTAEVIAMRGLGDPDAFPASDLGLRLAAKKLGLPAQRRALTVHSARWRPWRSYATQHLWTTLEHPVNQWPPQEKIA
What is the function of this protein?
The methylation of Alka by methylphosphotriesters in DNA leads to its activation as a transcriptional regulator that activates the transcription of its own gene and other alkylation resistance genes.
What are the official names of this protein?
Probable bifunctional transcriptional activator/DNA repair enzyme AlkA, Regulatory protein AlkA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the alkylbase DNA glycosidase AlkA family.
Protein: TRPG_CRYNJ
Sequence: MGFTLLIDNYDSFTWNIYADLASVGGNPYVVRNDKITLKEIEGMFSDGELERIVISPGPGHPRTDSGVSRDVIAWGMGKLPILGVCMGLECIVDLLGGEIAYAGEIKHGKTSLVQHDSIGVFHNLPQFLSSTRYHSLSAQIQSLPSVLQVTSTTKESGVIMGVRHRTYTVEAVQYHPESCMSEGGRGLMANFIQMKGGKWGGENAWCGVPAEGEEEQPKAKTNGAPSLPTILNRIHAQRLLDVEQAEKVPATSPANVSTSLSLYASPPLINFRDRMVSTPHTAVMAEIKRASPSKGDIAPTASAPEQALKYALAGASVISVLTEPTWFKGSLLDMLAVRNAVDSLPNRPAILRKDFVLSKYMIDEARLYGADTVLLIVAMLEPQQLKELYDYSVSLGMEPLVEVNNPTELSLALEIGSKVIGVNNRNLHDFNVDMSTTSRVNAALNGRDVVLCALSGISSHEDVEKYVKEGVKGVLVGEALMRASDTKAFLRSLIGLPPLEVVPKSRPLVKICGIRSTDDAKLAISAGADLLGVILVPGTKRCISTSTAREISALVQSARSQSSSKPLEPSLSSPWFTTQSDLLSSRRKPLLVGVFQNQSLSDILSAVEEIGLDLVQLHGDEPQAWAKFIPVPVVKVFRVSPEGIVRGGEFRRPGLNQAILLDAGGVSGGGGEGKAFPWEHAKRLIQSGEVGSEGHMPLPVILAGGLTPENVGQAIEQAGEGVWCVDVSSGVEGEGGKVKEKVEAFVKAVRG
What is the function of this protein?
Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
What are the official names of this protein?
Multifunctional tryptophan biosynthesis protein.
Protein: TRMD_CAMJE
Sequence: MKFSFVSLFPNLMEFYFQDSILARAKEKKLFKLNFYNPRDFSKNSYHKVDDYKIGGGAGLLMQAEPMYEVLRSIQEKKENPYFIFLNPSGKTFNQKDAKRLSKKEHIVFVCGRYEGIDERVLEIFANEVFSIGDFILTGGELPALVMCDAILRNVNGVLGNMESLEEESFENNLLEAPAFSKPFIFEKKNKKFYTPSEFLKGNHARIASLKTTLASCKTKFFRPDLFLEHERKK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_NATPD
Sequence: MKDYIRRVSDGEDLTQAEAREAASLVFEEATEAQIGALLSALRAKGETEPEIAGFAEGMRAAARRIDPDRSPLVDTCGTGGDGHDTINVSTTSSFVVAGAGVPVAKHGNYSVSSSSGSADVLEEIGVTIDAEPPAVETCIEETGMGFMLAPVFHPAMKAVIGPRKELGMRTIFNVLGPLTNPADADAQVVGVYDEALVPTLADALSRMSVDRALVVHGAGLDEIGVHGESTVAEVDGESVEQYTVTPSDLGVDSHDLSAVAGGSPTENAADMRGILEGDVEGAKRDIILANAGAAIYIAGEADSLAAGVDAARESIDTGAAAAQLASLREFEP
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: APRL3_ORYSJ
Sequence: MATRLLCWTALLLPIIAATAAASPLPEACPVPTAAEEILGPGGTCTTLDRRGDPVGVIEGDEVTLAKAITLLHMNKDDYIAVLFYASWCPFSQECKPNFEILASLFPSIRHFAFEESSIRPSIISRYGIHGFPTLFLLNSTMRVRYHGPRTVKSLAAFYRDVSGFDVSMTSEAVLHSVDGIELKKDAEQENCPFWWARSPEKILQQDTYLALATAFVILRLLYLLFPKIGSFAKRAWRRHTLFPNLVGVHEYFFTYLEQARHKFFRLYPSKRGNLQEGARNATAWASKSLASVSIGEPSTIGRTNSTNELR
What are the official names of this protein?
5'-adenylylsulfate reductase-like 3, Adenosine 5'-phosphosulfate reductase-like 3, APR-like 3, OsAPRL3.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PGPS2_ARATH
Sequence: MGEEDTATVDQNSFGGGKDSLLRNRHSSPLPSPTQLSSKVITLPTVLTLGRVAAVPILVATFYVDCWWGRTATTSIFIAAAITDWLDGYIARKMRLGSEFGAFLDPVADKLMVAATLILLCTKPMVAVVLGPVPWLVTVPSIAIIGREITMSAVREWAASQNGKLSEAVAVNSLGKWKTATQMIALTILLASRDSSFERLLPSGIGLLYVSAGLSIWSLVVYMRKIWRVLLKK
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2, Phosphatidylglycerophosphate synthase 2, PGP synthase 2.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein.
Protein: CSRP3_MOUSE
Sequence: MPNWGGGAKCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKVCYGRRYGPKGIGFGQGAGCLSTDTGEHLGLQFQQSPKPARAATTSNPSKFSAKFGESEKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKNFGPTGIGFGGLTQQVEKKE
What is the function of this protein?
Positive regulator of myogenesis.  Acts as cofactor for myogenic bHLH transcription factors such as MYOD1, and probably MYOG and MYF6.  Enhances the DNA-binding activity of the MYOD1:TCF3 isoform E47 complex and may promote formation of a functional MYOD1:TCF3 isoform E47:MEF2A complex involved in myogenesis (By similarity).  Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes.  Could play a role in mechanical stretch sensing.  May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures.  It is essential for calcineurin anchorage to the Z line.  Required for stress-induced calcineurin-NFAT activation (PubMed:9039266, PubMed:15665106).  The role in regulation of cytoskeleton dynamics by association with CFL2 is reported conflictingly.  Proposed to contribute to the maintenance of muscle cell integrity through an actin-based mechanism.  Can directly bind to actin filaments, cross-link actin filaments into bundles without polarity selectivity and protect them from dilution- and cofilin-mediated depolymerization; the function seems to involve its self-association (By similarity).  In vitro can inhibit PKC/PRKCA activity.  Proposed to be involved in cardiac stress signaling by down-regulating excessive PKC/PRKCA signaling (PubMed:27353086).
What are the official names of this protein?
Cysteine and glycine-rich protein 3, Cysteine-rich protein 3, CRP3, LIM domain protein, cardiac, Muscle LIM protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere. Note=Nucleocytoplasmic shuttling protein (By similarity). Mainly cytoplasmic. In the Z line, found associated with GLRX3 (via C- terminus).
Protein: PANC_SYNWW
Sequence: MQVFENITKMQEWAREQKKQGQSIALVPTMGYLHEGHLALVKEARRQCDKVVVSIFVNPIQFGAGEDFEQYPRDLEQDSALLEKERVDALFSPGIRDMYPGSFQTFVEVYGEITEKMCGASRPGHFKGVTTVVSKLFNICQPDRAYFGQKDAQQLMIVEKMVRELNFPLEIIRVPIVREKDGLAMSSRNVYLSPEERAEALVLYRALKMAEEEIKNGEREIGIIRQKMEEMIKACPRAAIDYIAINNANDLSELQTCAGKVLIALAVKFGKTRLIDNLIVEV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYOU1_CRIGR
Sequence: MAATVRRQRPRRLLCWTLVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTLKENERFLGDSAAGMAIKNPKATLRYFQHLLGKQADNPHVALYRDRFPEHELNIDPQRQTVRFQISPQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPAFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINSTAQNVMFYDMGSGTTVCTIVTYQTVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLREHLAKLFNEQRRGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVESEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVIYPILVEFTREVEEEPGVRSLKHNKRVLFSRMGPYPQGKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESLKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSPEEESTLTKLGNTISSLFGGGTSSDAKENGTDAVQEEEESPTEGSKDEPGEQGDLKEETEAPVEDTSQPPPPEPKGDAAPEGEKPDEKESGGKSEAQKPEEKGQSGPEGVPPAPEEEKKQKPARKQKMVEEIGVELAVLDLPDLPEDELARSVKKLEDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSATSTWLEDEGFGATTVMLKEKLAELKKLCQGLFFRVEERRKWPERLSALDNLLNHSSIFLKGARLIPEMDQIFTEVEMTTLEKVINDTWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRTEPPLNATAGDQEEKVIPPAGQPEEAKPILEPDKEETTTEPTDSEPLELGGPGAESEPKEQTAGQKRSSKNDEL
What is the function of this protein?
Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation.  May play a role as a molecular chaperone and participate in protein folding (By similarity).
What are the official names of this protein?
Hypoxia up-regulated protein 1, 150 kDa oxygen-regulated protein, ORP-150, 170 kDa glucose-regulated protein, GRP-170.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RS14Z_BACC7
Sequence: MAKKSMIAKQKRTPKFKVQEYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: NUDL_SHIFL
Sequence: MEYRSLTLDDFLSRFQLLRPQINREPLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVTP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.