PharMolix/UniProtQA huggingface dataset:
Protein: RSMB_CHICK
Sequence: MTVGKSSKMLQHIDYRMRCILQDGRVFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGAPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYTPGRGGPPPPMSRGAPPPGMMGPPPGMRPPMGPPMGMPPGRGAPMGMPPPGMRPPPPGMRGPPPPGMRPPRP
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein-associated protein B', snRNP-B', snRPB', Sm protein B', Sm-B', SmB'.
What is the protein family that this protein belongs to?
Belongs to the snRNP SmB/SmN family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: CAB_PRACR
Sequence: ASSASSPTTMLEERDRLENFRETGEAGHKDHLASPFEANIFTYGDRGTNVVAIFS
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated (By similarity).  May function in a far-red light-harvesting complex of photosystem II (Ref. 1).
What are the official names of this protein?
Chlorophyll a-b binding protein, chloroplastic, Far-red light-harvesting complex protein, frLHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
Protein: NTPP_HAEDU
Sequence: MHKKLYLASNSPRRWALLQNLGLALLPLASEIDETAHANEMAQDYCSRIAREKNQAAQAVRIRQNLAEYPILTADIMVSIDGEILGKPSHQQQAVEMLKKLSGRTHQVYTAVCVSANQQLFECIHSSEVTFKRLSEAEIYAYIATGEPMDKAGAYGIQALGGIFIQHLAGSFTGVMGLPIFETVALLKKVNIEVLPS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPE27_UPEMJ
Sequence: GIIDIAKKLVGGIRNVLGI
What are the official names of this protein?
Uperin-2.7.
What are the subcellular locations of this protein?
Secreted.
Protein: HCYA_TACTR
Sequence: TIKEKQASILALFEHLTSVPKQHIPEKERDNRLHDVGHLSRGKLFSLFHREHLEEATHLYEILHAAKNFDDFLLLCKQARDFVNEGM
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: DES6_CERPU
Sequence: MVSQGGGLSQGSIEENIDVEHLATMPLVSDFLNVLGTTLGQWSLSTTFAFKRLTTKKHSSDISVEAQKESVARGPVENISQSVAQPIRRRWVQDKKPVTYSLKDVASHDMPQDCWIIIKEKVYDVSTFAEQHPGGTVINTYFGRDATDVFSTFHASTSWKILQNFYIGNLVREEPTLELLKEYRELRALFLREQLFKSSKSYYLFKTLINVSIVATSIAIISLYKSYRAVLLSASLMGLFIQQCGWLSHDFLHHQVFETRWLNDVVGYVVGNVVLGFSVSWWKTKHNLHHAAPNECDQKYTPIDEDIDTLPIIAWSKDLLATVESKTMLRVLQYQHLFFLVLLTFARASWLFWSAAFTLRPELTLGEKLLERGTMALHYIWFNSVAFYLLPGWKPVVWMVVSELMSGFLLGYVFVLSHNGMEVYNTSKDFVNAQIASTRDIKAGVFNDWFTGGLNRQIEHHLFPTMPRHNLNKISPHVETLCKKHGLVYEDVSMASGTYRVLKTLKDVADAASHQQLAAS
What is the function of this protein?
Fatty acid desaturase able to introduce a delta(6)-double bond into delta(9)-unsaturated fatty-acid substrates.  Has a strong preference for linoleic acid (18:2(9Z,12Z)).
What are the official names of this protein?
Acyl-lipid (9-3)-desaturase, Delta 6-fatty acid desaturase, CpDES6.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BUB3_DICDI
Sequence: MSNEPTSSFYELRLPPSDGISSVNFCPNSVNLLVTSWDSTVRCYDTQNNVQKWQYNHKGPVMDGCFPEKNKVFSGDVFGSVKHYDPVAGVEKEVGSHEDGVRSVVYNSDTQQLFTGGWDQQLKLWDIRSDKMEISNHDLQSKIFTMDVSPISNMLVIGTADKYVTIYDTRQMETHLQKRESSIKYQTRCIRTFTDGKGYALASVEGRIAMEYFDPSPAVQSKKYAFKCHRLTESGVDVVYPVNCIAFNPHYGTFATGGCDKNVFFWDGANRKRLHALKTYPTSISSMSFNTDGNILAVASSYTFEEGEKDHPPDQIFIHNILSEKIIKPIK
What is the function of this protein?
Involved in cell cycle checkpoint enforcement.
What are the official names of this protein?
Mitotic checkpoint protein bub3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BUB3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RXL7_HALH5
Sequence: MSYEKVSQATDLVIGTKQTLKALEQEEVLEVVIAKDAEPRVVNKVEAMASVKQIPIIYVDSMKKLGKACGIDVGAATVALKK
What are the official names of this protein?
Putative ribosomal protein L7Ae-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: RLMF_BACTN
Sequence: MAERSELHTRNKHNGQYDFSLLTENYPPLRKFVLLNPLGIQTIDFFNPHAVKALNKALLISYYGIRYWDIPRNYLCPPIPGRADYVHYIADLIDPERVSNTANEENGDKPKRQCRCLDIGVGANCIYPIIGHVEYGWMFVGSDIDPVSIENARKIVTCNPVLAHKIDLRLQKDNRRIFDGIIAPDEYFDVTICNPPFHSSKKEAEEGTLRKLSSLKGEKVKKTKLNFGGNANELWCEGGELRFLLNMISESRKYRKNCGWFTSLVSKEKNLDKLYAKLKAVHVSEYKIIRMCQGTKNSRILAWRFLE
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALO1_ACRLO
Sequence: CIKNGNGCQPDGSQGNCCSRYCHKEPGWVAGYCR
What is the function of this protein?
Has antifungal activity against C. glabrata.
What are the official names of this protein?
Antimicrobial peptide Alo-1.
What is the protein family that this protein belongs to?
Belongs to the AMP family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASP5_STRGN
Sequence: MQKLLLILTILLALILITLVISLPRENQQFFSETRSTIGKSGYWETNFFKKIILLIVSILLFLTLIFYMIQTA
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required to export GspB, a serine-rich repeat cell wall protein encoded upstream in the same operon.
What are the official names of this protein?
Accessory secretory protein Asp5, Orf6.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL29_LACDB
Sequence: MKTKEIRSLSTDELLAKEKQYKEELFNLRFQQATGQLENTARLSQVRKNIARIKTILSEKELEQN
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SY111_ARATH
Sequence: MNDLMTKSFMSYVDLKKAAMKDMEAGPDFDLEMASTKADKMDENLSSFLEEAEYVKAEMGLISETLARIEQYHEESKGVHKAESVKSLRNKISNEIVSGLRKAKSIKSKLEEMDKANKEIKRLSGTPVYRSRTAVTNGLRKKLKEVMMEFQGLRQKMMSEYKETVERRYFTVTGEHANDEMIEKIITDNAGGEEFLTRAIQEHGKGKVLETVVEIQDRYDAAKEIEKSLLELHQVFLDMAVMVESQGEQMDEIEHHVINASHYVADGANELKTAKSHQRNSRKWMCIGIIVLLLIILIVVIPIITSFSSS
What is the function of this protein?
Involved in cytokinesis.  Acts as a cell plate-specific syntaxin, required for the fusion of vesicles at the plane of cell division.
What are the official names of this protein?
Syntaxin-related protein KNOLLE, Syntaxin-111, AtSYP111.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: CYB_PELMA
Sequence: MAPNLRKSHPLLKMINNSLIDLPTPSNISAWWNFGSLLGICLATQILTGLLLAMHYTADTTLAFSSVTHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLYKETWNTGILLLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTIVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGLTLIHLTFLHESGSNNPLGLVSNCDKIPFHPYFSLKDILGFMLMFLSLTTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLMMFLSPLLHKSKQRTMAFRPLSQLLFWTLVANLFILTWVGSQPVEHPFIIIGQLASFTYFTILLILLPITGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSTS_BACSU
Sequence: MKKNKLVLMLLMAAFMMIAAACGNAGESKKSNSDSAKGEEKASGSLTISGSSAMQPLVLAAAEKFMEENPDADIQVQAGGSGTGLSQVSEGAVQIGNSDVFAEEKEGIDAKALVDHQVAVVGMAAAVNPDAGVKDISKDELKKIFTGKIKNWKELGGKDQKITLVNRPDSSGTRATFVKYALDGAEPAEGITEDSSNTVKKIIADTPGAIGYLAFSYLTDDKVTALSIDGVKPEAKNVATGEYPIWAYQHSYTKGEATGLAKEFLDYLKSEDIQKSIVTDQGYIPVTDMKVTRDANGKQS
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS15_ALKMQ
Sequence: MERTEKKSIIDTFKTHENDTGSPEVQIALLTDRINHLNDHLKTHKKDHHSRRGLLKMVGQRRNLLNYLKDNQIERYREVIARLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TSAD_RICRO
Sequence: MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSHLDKALKNVLKESNTKLTDISTIAATSGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAVGEAFDKVAKMLNLAFPGGPEIEKRAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMNLKEINDTVINDIAASFQFTIGEILSSKVQDAIRAYEQITNNFDKKNIVIAGGVAANKYLQKILSSCAKTYGYRLIYPPIHLCTDNAAMIAYAGLERYNNKLFTPLNFSPKARWSLEDISN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPOB_SODGM
Sequence: MKKRALIVLAALVLASCTSRKPASPPAPIEPVPPPVTVSVQPPPPATSEPVPMPPKIKTIDWQASLSPLVQQMLAVEGINDGSVLLVNTMKNTTNGSVQTGKATAALTRLITDAGGKFQVVGANQLNAARQMLGLSADDSLESRSKAVGLARYLNAQYVLYSAAAGDVKQPTLDLQLMLVQTGEIIWSGNGVAQD
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
What are the official names of this protein?
Penicillin-binding protein activator LpoB, PBP activator LpoB.
What is the protein family that this protein belongs to?
Belongs to the LpoB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: RS9_SACD2
Sequence: MAAEQYYGTGRRKTSTARVFLTLGGGKITVNGKTLDEYFGREVARMIVRQPIELTDNVEKFDINVTVKGGGSFGQAGAIRHGLTRALMAYDEAMRPTLRAAGYVTRDAREVERKKVGLRKARKKPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: WDHD1_HUMAN
Sequence: MPATRKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRIWEDLDDDDPKFINVGEKAYSCALKSGKLVTAVSNNTIQVHTFPEGVPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSVRVWQISDQTCAISWPLLQKCNDVINAKSICRLAWQPKSGKLLAIPVEKSVKLYRRESWSHQFDLSDNFISQTLNIVTWSPCGQYLAAGSINGLIIVWNVETKDCMERVKHEKGYAICGLAWHPTCGRISYTDAEGNLGLLENVCDPSGKTSSSKVSSRVEKDYNDLFDGDDMSNAGDFLNDNAVEIPSFSKGIINDDEDDEDLMMASGRPRQRSHILEDDENSVDISMLKTGSSLLKEEEEDGQEGSIHNLPLVTSQRPFYDGPMPTPRQKPFQSGSTPLHLTHRFMVWNSIGIIRCYNDEQDNAIDVEFHDTSIHHATHLSNTLNYTIADLSHEAILLACESTDELASKLHCLHFSSWDSSKEWIIDLPQNEDIEAICLGQGWAAAATSALLLRLFTIGGVQKEVFSLAGPVVSMAGHGEQLFIVYHRGTGFDGDQCLGVQLLELGKKKKQILHGDPLPLTRKSYLAWIGFSAEGTPCYVDSEGIVRMLNRGLGNTWTPICNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQIATEKGQMEEQFWRSVIFHNHLDYLAKNGYEYEESTKNQATKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVNLAIKYASRSRKLILAQKLSELAVEKAAELTATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDSGEADDEEKPEIHKPGQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSASSKEPAMSMNSARSTNILDNMGKSSKKSTALSRTTNNEKSPIIKPLIPKPKPKQASAASYFQKRNSQTNKTEEVKEENLKNVLSETPAICPPQNTENQRPKTGFQMWLEENRSNILSDNPDFSDEADIIKEGMIRFRVLSTEERKVWANKAKGETASEGTEAKKRKRVVDESDETENQEEKAKENLNLSKKQKPLDFSTNQKLSAFAFKQE
What is the function of this protein?
Core replisome component that acts as a replication initiation factor.  Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork.
What are the official names of this protein?
WD repeat and HMG-box DNA-binding protein 1, Acidic nucleoplasmic DNA-binding protein 1, And-1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: RS17E_SULIK
Sequence: MGNIYTKDIKRIVKEIYNQYKDEIKDDYNTNKQIVVRYVDVKSKKVRNRIAGYLTRYYKIMKEKETSPTEEKEEISEEI
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: RS19_MYAAR
Sequence: MGISVKDVSSHEFTRAFAAFLKKSGKMKVPEWTDFVKTGMFKELSPYEPDWYFIRAASICRHLYIRSPAGIGSFEKIYGGRRRRGTAPSHFCKANGSISRRLLQSLEGLKIVEKDPNGGRRLTSQGRRDLDRIAAQIAPKRAPSAPKTV
What are the official names of this protein?
40S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: YAHD_ECOLI
Sequence: MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAITLASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVTRFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIVQLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA
What are the official names of this protein?
Putative ankyrin repeat protein YahD.
Protein: RHAS_SHIB3
Sequence: MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFHREFNWSPRDIRQGRDGFLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KVD43_HUMAN
Sequence: MDMRVPAQRLGLLLLWFPGARCAIRMTQSPFSLSASVGDRVTITCWASQGISSYLAWYQQKPAKAPKLFIYYASSLQSGVPSRFSGSGSGTDYTLTISSLQPEDFATYYCQQYYSTP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 1D-43.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: YUC1_ARATH
Sequence: MESHPHNKTDQTQHIILVHGPIIIGAGPSGLATSACLSSRGVPSLILERSDSIASLWKSKTYDRLRLHLPKHFCRLPLLDFPEYYPKYPSKNEFLAYLESYASHFRIAPRFNKNVQNAAYDSSSGFWRVKTHDNTEYLSKWLIVATGENADPYFPEIPGRKKFSGGKIVHASEYKSGEEFRRQKVLVVGCGNSGMEISLDLVRHNASPHLVVRNTVHVLPREILGVSTFGVGMTLLKCLPLRLVDKFLLLMANLSFGNTDRLGLRRPKTGPLELKNVTGKSPVLDVGAMSLIRSGMIQIMEGVKEITKKGAKFMDGQEKDFDSIIFATGYKSNVPTWLQGGDFFTDDGMPKTPFPNGWRGGKGLYTVGFTRRGLLGTASDAVKIAGEIGDQWRDEIKGSTRNMCSSRFVFTSKS
What is the function of this protein?
Involved in auxin biosynthesis, but not in the tryptamine or the CYP79B2/B3 branches.  Catalyzes in vitro the N-oxidation of tryptamine to form N-hydroxyl tryptamine.  Involved during embryogenesis and seedling development.  Required for the formation of floral organs and vascular tissues.  Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots.
What are the official names of this protein?
Probable indole-3-pyruvate monooxygenase YUCCA1, Flavin-containing monooxygenase YUCCA1.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: CKLF6_HUMAN
Sequence: MENGAVYSPTTEEDPGPARGPRSGLAAYFFMGRLPLLRRVLKGLQLLLSLLAFICEEVVSQCTLCGGLYFFEFVSCSAFLLSLLILIVYCTPFYERVDTTKVKSSDFYITLGTGCVFLLASIIFVSTHDRTSAEIAAIVFGFIASFMFLLDFITMLYEKRQESQLRKPENTTRAEALTEPLNA
What is the function of this protein?
Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity.  Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination.  May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
What are the official names of this protein?
CKLF-like MARVEL transmembrane domain-containing protein 6, Chemokine-like factor superfamily member 6.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Co-localizes with PD-L1/CD274 in the plasma membrane and in recycling endosomes.
Protein: NHAA_PHOLL
Sequence: MTAIIRQFLKLEAAGGLLLIITAIIALIMANSPLQGIYQQFLNISVAVQFAALEINKPLLLWINDGLMAVFFLIVGLEVKRELLEGSLAGRDKALFPVIAAIGGMVAPALIYLLFNGNDEFTRQGWAIPAATDIAFALGVMALLSKRVPTELKVFLLALAIIDDLGVIVIIALFYTKTVSLVALGLSAAMIALLVWMNWRGVEKTSAYLAVGAILWVCILKSGVHATLAGVIVGFLIPLRGQNGHSPSELLEHGLHPWVAYLILPLFAFANAGVALNGVTLNGLTDILPLGIAVALFLGKPLGIFLFSYISIQIGFAKLPQQINLKQIFAVSVLCGIGFTMSIFISGLAFEGVDESFSVYSRLGILMGSTIAAFMGYGLLRMVLPKKK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y656_SHESM
Sequence: MEYEFRRNSLTGTYLASFSMDHEVLGQWFSEELGPELAKIQQVLDIIKDIQAGKRDSWRLIGGDLTLDLDEEQARIYANALGFEQEYELEESMSLYDAESEAYCGLEDLEEALLSWYEFVEKGR
What are the official names of this protein?
UPF0231 protein Shewmr4_0656.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: HEMO_CHICK
Sequence: RPLTQHKPHTPGDEHPHGAEPPGXDTALAQIXGD
What is the function of this protein?
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
What are the official names of this protein?
Hemopexin.
What is the protein family that this protein belongs to?
Belongs to the hemopexin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CH60_CHLTA
Sequence: MVAKNIKYNEEARKKIQKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEVELADKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYTEGLRNVTAGANPMDLKRGIDKAVKVVVDQIKKISKPVQHHKEIAQVATISANNDAEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDVVEGMNFNRGYLSSYFATNPETQECVLEDALVLIYDKKISGIKDFLPILQQVAESGRPLLIIAEDIEGEALATLVVNRIRGGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLISEELGMKLENANLAMLGKAKKVIVSKEDTTIVEGMGEKEALEARCESIKKQIEDSSSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATIAAVEEGILPGGGTALIRCIPTLEAFLPMLTNEDEQIGARIVLKALSAPLKQIAANAGKEGAIIFQQVMSRSANEGYDALRDAYTDMLEAGILDPAKVTRSALESAASVAGLLLTTEALIAEIPEEKPAAAPAMPGAGMDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDLC_XENLA
Sequence: MIPPADSLLKHDNPVLISKNTERKSPKSRPLKVSSPQTVLTAPVPPPPKPKTPLLDATKPAEEILNAILPPREWVENNQLWIQQVSSTPSTRMDVVHLQEELDMKLQQRQARETGICPVRRELYSQCFDELIRQVTINCAERGLLLLRVRDEIHMTISAYQTLYESSVAFGMRKALQAEQGKSDMEKRMADLEMEKKDLERQVNEQKAKCEAIEKREAERRQVEEKKHAEEIQFLKRTNQQLKAQLEGIIAPKK
What is the function of this protein?
May play a dynamic role in flagellar motility.
What are the official names of this protein?
Axonemal dynein light intermediate polypeptide 1, Inner dynein arm light chain, axonemal.
What is the protein family that this protein belongs to?
Belongs to the inner dynein arm light chain family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cell projection, cilium, flagellum. Dynein axonemal particle. Cytoplasm.