PharMolix/UniProtQA huggingface dataset:
Protein: FENR1_BACHK
Sequence: MNREELFDVTVIGGGPAGLYSAFYSGLREMKTKIIEFQPQLGGKIHVYPEKMIWDIGGLLPVTGEKLIEQLVQQGLTFQPEVVLNTKIESIIRNKDGIFTLKTSTGEEHFSKTVIVATGSGILNPQKLSIEGAERFEVSNLNYTVKSLKRFKNKTVIISGGGNSAIDWANELEPIAKKVYLTYRKEELSGHEAQVKQLMNSSAECFFNTSITTLIAGDNHEAIEYVELTNHETGEVSQLAIDEVIINHGYERDITLLENSELDVAIIDNYYIAGNANSESSVDGLYAAGDILKHEGKLHLIAGAFQDAGNAVNKAKQFIQPDASEYGMVSSHNEVFKKRNRELIKQMMK
What are the official names of this protein?
Ferredoxin--NADP reductase 1, FNR 1, Fd-NADP(+) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: KAX95_BUTOC
Sequence: VGCEECPMHCKGKHAVPTCDDGVCNCNV
What is the function of this protein?
Blocks voltage-gated potassium channels Kv1. 1/KCNA1 (IC(50)=145 nM), Kv1. 2/KCNA2 (IC(50)=2. 5 nM), and Kv1. 3/KCNA3 (IC(50)=15).  Also inhibits calcium-activated potassium channels (KCa/KCNN).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 9.5, Kbot1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 09 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_RHIWR
Sequence: MAKPTTVKIKLVSTADTGFFYVTKKNPRTQTEKLSFRKYDPVVRKHVDFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: BIOH_SHEWM
Sequence: MSSSLHIESIGQGQELVILHGWGVNSSVFTPLHASLSEYRVHYVDLPGFGHSDPIDGDLDDWVDAIINQLPNTAIWIGWSLGGLVATKAALRYPEQVRGLVTIASSPCFMAREDESWPGIPPQVLSQFSTQLQQNIGKTIERFLAIQVMGSATAKEDIKQLKELVLSRPLPKNSALAQGLKMLENIDLRAQLPQIEQPWLRVWGRLDGLVPRRVPPLMPNHQAHFTDLLLPKASHAPFLSHRDEFLTGLTDWLNKF
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHPS2_MYCBO
Sequence: MRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA
What is the function of this protein?
Has very low affinity for the DHPS substrate 6-hydroxymethyl-7,8-dihydropterin-pyrophosphate, but can bind the inhibitor dapsone.  Seems to lack dihydropteroate synthase activity, and does probably not function in folate metabolism (By similarity).
What are the official names of this protein?
Inactive dihydropteroate synthase 2, DHPS 2, Dihydropteroate pyrophosphorylase 2.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: LFG1_BOVIN
Sequence: MSHEKSFLVSGDSYPPPNPGYPGGPQPSMAPYPGAPYPQAPFQPSPYGQPGYPQGPSPYPQGGYPQGPYPPGGYPQGPYPPGGYPQGPYPPGGYPQGPYPQSPFPPNPYGQPQAFPAQDPGSPHHGNYHEEGPPSYYDNQDFPATNWDDKSIRQAFIRKVFLVLTLQLSVTLSTVAVFTFVGEVKGFVRENVWTYYVSYAIFFVSLIVLSCCGDFRRKHPWNLVALSILTVSLSYMVGMIASFYNTEAVIMAVGITTTVCFTVVIFSMQTRYDFTSCVGVLLVSVVVLILFAILCIFIRSRVLEIVYASLGALLFTCFLAVDTQLLLGNKQLSLSPEEYVFAALNLYTDIINIFLYILTIIGRAKE
What is the function of this protein?
Potential apoptotic regulator.
What are the official names of this protein?
Protein lifeguard 1, Glutamate [NMDA] receptor-associated protein 1, NMDA receptor glutamate-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the BI1 family. LFG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COBQ_CLOBA
Sequence: MNKKNIMFLGTASSVGKSTLVAALCRVLKNEDFKVSPFKAMNISLNSYVTKDGAEMGRAQVVQAEASKIEPSALMNPILLKPSGGHTQVIVNGKVYDNIEPYEYKELNKKLKGIVKESYDRISNEYDLIVLEGSGGCAEINLKDTDIANMNMAECVDAPVILVADIDRGGVFASIVGTLNLLSENERKRVKGVIINKFRGKKEYFEPGVKQLEDIIKIPVLGVMPYEYFDIDDEDSVTEKISNKESTEAKNIDIAIIRLSHMSNFTDFNVLNRINGVNIRYVESTKYLKNPDVIIIPGTKNTIEDLRILKESKLANEIIKLHESGTLVFGICGGYQMLGKLLLDQQGVEGSTFQEEGLGLLDIKTRFNERKVTKQVEAQVVSNLKHINEIENKSLVGYEIHNGISKVGKNAKPFIKDSKGKIIGVCDMEGSVAGTYLHGIFDSEEFTNSFINALKKNNNFELLENDELDKVSDYKNEQYEKLAKVFSDNIDVSKIKEIMGI
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: PLSY2_OCEIH
Sequence: MDYVIFGLVAYLLGSIPSALIVGKVGYNIDIREHGSGNLGATNTFRILGTKAGSIVTLADILKGTLATVLPQLFDANVYVLAIGLLAVVGHMYPIFAKFRGGKAVATSGGMILGMYPLLFVIMVTTFLLTLYISKYVSLSSIITGLVSLLITIFYQDLGLSIVVFLLSAIVCYRHRENIKRIKNGTEPKISWM
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 2, Acyl-PO4 G3P acyltransferase 2, Acyl-phosphate--glycerol-3-phosphate acyltransferase 2, G3P acyltransferase 2, GPAT 2, Lysophosphatidic acid synthase 2, LPA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YZ04_AQUAE
Sequence: MKVIKKTVLLKVYEPNKGKKECLDRVIDLYAKTLDFYLDVIKKAGIYRIVALARKKKERKSGRKSNYALNLLEKLTVPTQAHPNPLYPIPFSVRVDIRRSAINQAIGMVSSYVSNLKNWYEEGKELGHSKPSYPNPKSYSPQLYSTLVELDDLLVRENKEFHFVRIKVLNEKER
What are the official names of this protein?
Uncharacterized protein aq_aa04.
Protein: MBL2_PONPY
Sequence: MSLFPSLPLLLLSVVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDCDSSLAASERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRDAAENRAIRNLIKEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDIPCSSSHLAVCEFPI
What is the function of this protein?
Calcium-dependent lectin involved in innate immune defense.  Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway.  Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
What are the official names of this protein?
Mannose-binding protein C, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin.
What are the subcellular locations of this protein?
Secreted.
Protein: FBXL2_HUMAN
Sequence: MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQTDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL
What is the function of this protein?
Calcium-activated substrate recognition component of the SCF (SKP1-cullin-F-box protein) E3 ubiquitin-protein ligase complex, SCF(FBXL2), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:22020328, PubMed:22323446).  Unlike many F-box proteins, FBXL2 does not seem to target phosphodegron within its substrates but rather calmodulin-binding motifs and is thereby antagonized by calmodulin (PubMed:22020328, PubMed:22323446).  This is the case for the cyclins CCND2 and CCND3 which polyubiquitination and subsequent degradation are inhibited by calmodulin (PubMed:22020328, PubMed:22323446).  Through CCND2 and CCND3 degradation induces cell-cycle arrest in G(0) (PubMed:22020328, PubMed:22323446).  SCF(FBXL2) also mediates PIK3R2 ubiquitination and proteasomal degradation thereby regulating phosphatidylinositol 3-kinase signaling and autophagy (PubMed:23604317).  PCYT1A monoubiquitination by SCF(FBXL2) and subsequent degradation regulates synthesis of phosphatidylcholine, which is utilized for formation of membranes and of pulmonary surfactant (By similarity).  The SCF(FBXL2) complex acts as a regulator of inflammation by mediating ubiquitination and degradation of TRAF proteins (TRAF1, TRAF2, TRAF3, TRAF4, TRAF5 and TRAF6) (By similarity).  The SCF(FBXL2) complex acts as a negative regulator of the NLRP3 inflammasome by mediating ubiquitination and degradation of NLRP3 (PubMed:26037928).
What are the official names of this protein?
F-box/LRR-repeat protein 2, F-box and leucine-rich repeat protein 2, F-box protein FBL2/FBL3.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: KIF1C_RAT
Sequence: MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSRMFLKASFDYSYWSHTSVEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVNVNQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRSHDQLTGLDSEKVSKISLVNLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADLQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAVINEDPNARLIRELQEEVARLRELLMAQGLSASALGGLKVEEGSPGGVLPAASSPPAPASPSSPPPHNGELEPSFSPSAEPQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGSPGGWRTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDVDIKLTGQFIREQHCLFRSIPQPDGEVMVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKDWLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGEDSDKRSCEESWRLISSLRDELPPNTVQTIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPEGPGDAWRAVARDVWDTVGEEEGCGGGGGGGEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLTQDLEDDNEESGLVTWAPPEGSEAVEEAVSNDHSPAVRPSSPPQSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGSGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPGPQPPEEVTAPPPPPNRRPPSPRRPHRPRRNSLDGGSRSRGGGSTQPEPQHLRPQKHNSYPQQPQPYPAQRPGPRYPPYTTPPRMRRQRSAPDLKESGAAV
What is the function of this protein?
Probable motor protein.
What are the official names of this protein?
Kinesin-like protein KIF1C, Kinesin-like protein KIF1D.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PSBH_KLEBI
Sequence: MATKTLDQDPNKQRPGAAVSSVLKPLNAEYGKVAPGWGTTVLMGVFMALFAVFLVIILELYNASVLLDGVPVSWQSVQS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS12_PSESM
Sequence: MATINQLVRQPRKRIVEKSDVPALQNCPQRRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTSGVKGRNQGRSKYGTKKPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DHPS_STAES
Sequence: MIKTKIMGILNVTPDSFSDGGQYHSVDQAVKRAKEMIDEGVDIIDVGGVSTRPGHKEVSHKEVSLKEEMNRVLPVVESIVKYDVQISVDTFRSEVAEACLKLGVSMINDQWAGLFDSNMFNVVSQYGAEIVLTHNGDGHRDKPVVEEMLVSLLAQANKAELAGIPHNKIWLDPGIGFPKTREEENEVMARLDELVATEYPVLLATSRKRYIKEMMNQDSSPSDRDEATAATTAYGIMKGVRGVRVHNVLLNTRLAQSMDFLKENEYERHHLS
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: SRF4_ARATH
Sequence: MGPNLQRIVLVFIACFGIFTSVVLAKTDSQDVSALNDAYKSMNSPSKLKGWSSSGGDPCGDSWDGITCKGSSVTEIKVSGRGLSGSLGYQLGNLKSLTYLDVSKNNLNGNLPYQLPDKLTYLDGSENDFNGNVPYSVSLMNDLSYLNLGRNNLNGELSDMFQKLPKLETIDLSSNQLTGKLPQSFANLTGLKTLHLQENQFKGSINALRDLPQIDDVNVANNQFTGWIPNELKNIGNLETGGNKWSSGRAPSPPPGTRHIDRNSSGGGGGSSKALTLGVIIAVSSIGGLILFAGLIALISRRKNSNDSSHFFDDEKGTNRSKPLFTPQSSQMLQFDNMEEFKNQKTVDSNTSLETKPSVKRTSSVSFKNSPTFHLIPSTQVAATPDRSSTSQDSPDTRGVKAFSLADLQNTASCFSPNRLLGEGTIGRVYKAKFQDGRKFAVKEIDSSLLGKGNPEEFSHIVSSISSIHHKNMAELVGYCSEQGRNMLVYEYFTSGSLHRFLHLSDDFSKPLTWNTRIRIALGTAKAIEYLHETCSPPLVHKNIKSSNILLDNELNPRLSDYGLANFHHRTSQNLGVGYNAPECTDPSAYTQKSDVYSFGVVMLELLTGRKPYDSGRPKAEQSLVRWAKPQLKDMDTLDEMVDPALCGLYAPESVSSFADIVSICVMTEPGLRPPVSNVVEALKRLV
What is the function of this protein?
Acts as a direct positive regulator of leaf size but not leaf shape.
What are the official names of this protein?
Protein STRUBBELIG-RECEPTOR FAMILY 4, Leucine-rich repeat receptor kinase-like protein SRF4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MSBA_POLSJ
Sequence: MTQLSEPVPVSLAARRSLWQRVARVWPYFSGSRAGWALAIGATIVASATEPFVPALLKPLLDRGFQRDSFNLWLVPLALMLLFTVRGLSGFLAQFALAKVTNDGLLKLRGAMFDKLLSARLTLFADQSSSAIANTVVYEVFNGSSMLINAIMKLARDVLTLLALIGYLVYLNWKLMLVVALLFPAVAFVIQVLSKRLYRLTKESQTATDDLAYVVEENVMAHRDVRLHGAQAGQASRFNHLSNSLRRLSMKSTAAYAGMSAITQVLAAMALSAVISIALLQSAENTTTVGGFVAFVTAMLLLIAPVKSLSDAATPVTRGLAALERGLDLMNLTPDESGGSFVKARAHGDIEFADVSVIYKADAAAALDQFSLSIKAGETLAIVGASGSGKTTLVNLLPRFVEMSSGNIYLDGQDLRAWNLASLRAQFAFVSQHVVMLNNSIAVNVALGQPVDRARVTECLAAANLSGLLAELPGGIDTILGHNAMQLSGGQRQRLAIARALYKNAPILVLDEATSALDTESELAVQEAIKRLTASRTSLVIAHRLSTVQHADRIIMMEAGRMIESGTHAELLARNGAYAHLYRLGFRNT
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSD_BACC1
Sequence: MRRTLYRLMIELTNGRFTSYILRKFAQSRLSSIIIPSYAKVFQINQDEMEKGLKEYRTLHELFTRKLKEGKRSIDTDASSIVSPVDGVFADHGPIEETKTFDIKGKRYSIVDMLGNEERAQRYAGGTYMVIYLSPSHYHRIHSPLSGSVTERFVLGRKSYPVNAAGMEYGKEPLSKNYRSVTEVNSDGEHMALVKVGAMFVNSIELLHERDTVQKGEEMAYFTFGSTVVLLFEKDMIEVVQELKSGQELRLGEKIATRLAHK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DGGGP_METM7
Sequence: MDIKAYFELIRLKNCLTASFGAFIGGLIASYFNLATVYDLILASIVVFLVCGFGNALNDIYDLKIDKINKPERPIPSKRLSLTDARVFSYLLVFVGLFISLFNMACFLMAVLNSIVLQQYASTYKKNKIIGNLIVAYLTGSVFIFGGIAVGNIDVTIMLFLCALFAMWSREIIKDYEDIEGDIQEKVISIPIKCGEKSVYIAAFLLVFAVFLSPLPYLFGFFGIYYMLSVVFCDLLFLIGIYNLVKNPSKKEAKKASRNIKIVTNLVLIAFLIGSLFK
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP).  This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Digeranylgeranylglyceryl phosphate synthase, DGGGP synthase, DGGGPS, (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, Geranylgeranylglycerol-phosphate geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: STHA_SALG2
Sequence: MPHSWDYDAVVIGSGPGGEGAAMGLVKQGARVAVIERYHNVGGGCTHWGTIPSKALRHAVSRIIEFNHNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQGFYERNHCEILQGNAHFIDEHTLALECHDGTVETLTAEKFVIACGSRPYHPNDVDFSHPRIYDSDSILSLHHEPRHVIIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQEMSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTDSLALENIGLETDSRGQLKVNSMYQTALPHVYAVGDVIGYPSLASAAYDQGRIAAQALVKGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMNVGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_NEIMA
Sequence: MKKIGLFGGTFDPIHNGHLHIARAFADEIGLDAVVFLPTGGPYHKDAASASAADRLAMVELATAEDARFAVSDCDIVREGATYTFDTVQIFRQQFPSAQLWWLMGSDSLMKLHTWKKWQMLVRETNIAVAMRQGDSLHQTPRELHAWLGKSLQDGSVRILSAPMHNVSSTEIRRAGVSDGIPPAAARYIREHGLYEK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: BIOB_ACIC1
Sequence: MTDVLASAERVLRDGIGLTEPELRAVLDVDDDSLPRLLDLAHRVRRRWCGPGVEIEGIVSVKTGGCPEDCHFCSQSGRFDSPVRSAWLDIPNLVTAAEQTAATGATEFCIVAAVRGPDDRLMRQVRAAVRAIREAVDINISCSLGILTPDQAAELAEIGVHRYNHNLETARSYFPSVVTTHTWEERWQTLQLVRAAGMEVCCGGILGMGESLDQRAEFAAQLADLDPDEVPLNFLDPRPGTPFADLPVVSVAEALRAAAMFRLALPRTILRFAGGREITLGDAGTRDALRGGVNGLIVGNYLTTLGRDPAADLALLAELGEPIRRSELQALSQAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ACOX4_ARATH
Sequence: MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASFKPATRSRL
What is the function of this protein?
Catalyzes the desaturation of short-chain acyl-CoAs to 2-trans-enoyl-CoAs (PubMed:10212254, PubMed:15743450).  Active on butyryl-CoA (C4), hexanoyl-CoA (C6), and octanoyl-CoA (C8) (PubMed:10212254).  Has no activity as acyl-CoA dehydrogenase or on crotonyl-CoA (an unsaturated C4:1 carbocyclic ester) or glutaryl-CoA (a dicarboxylic ester) (PubMed:10212254).  Peroxisomal fatty acid beta-oxidation is essential for embryo development (PubMed:12682048).  Acts as a suppressor of transcriptional silencing (PubMed:31064880).  Required for nuclear histone acetylation and DNA demethylation at some endogenous genomic loci (PubMed:31064880).
What are the official names of this protein?
Acyl-coenzyme A oxidase 4, peroxisomal, AOX 4, G6p, Short-chain acyl-CoA oxidase, AtCX4, AtG6, SAOX.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Glyoxysome. Peroxisome.
Protein: MSRQ_ECO24
Sequence: MRLTAKQVTWLKVSLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLRSLFNRLRKQVHNKLSV
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDD_ERWT9
Sequence: MHPRFQTAFATLSPLLQQAIRPILSSADFAGFISAQQADGVKQQCGLDDSELAFTLLPLAAACAVAPLSDFNVGAVARGKSGTLYFGANMEFVGATMQQTVHAEQSAVTHAWLRGESGLAGITVNYTPCGHCRQFMNELNSGTDLTIELPGRAAATLGHYLPDSFGPRDLAITTLLMDEVDHGIAPRGDKLEQAALAAANQSHAPYSGACSGVALQTRSGAIYAGRYAENAAFNPSLPPLQGALNLLNLGGEELSDIRRAVLAEASGAKLSQRSASAATLAALGCHDLITIPLVKM
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: CYC6_SYNP6
Sequence: MKRILGTAIAALVVLLAFIAPAQAADLAHGGQVFSANCAACHLGGRNVVNPAKTLQKADLDQYGMASIEAITTQVTNGKGAMPAFGSKLSADDIADVASYVLDQSEKGWQG
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.