PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_DESDA
Sequence: MDNLLTALILSIVEGLTEFLPVSSSGHLILAGDLLGFVGEKAATFDVVIQLGAIMAVVVLYWKRFWGLVRPQPYARFAGRRGIVLLMLTSLPACILGLLLHAYIKEYLFRPATVLIALVVGAICMILVEKRKFKPTCISLDDMTPRLALGIGCFQCLALWPGFSRSAATIMGGMLLGAKRPLAAEYSFIAAVPIMVAATGYDLLKNLSMFTAADIPFFLVGMIGSFVSALLAVKVFVALVGRMTLIPFACYRLLIAPFVYYFMVN
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BLH_HALSA
Sequence: MGASPVALTPLTARARRTLARPALALGWVAISIAALPAITGVSLSPTARYAPLVASAVVFGMPHGAIDYLALPRAVTGTVTVRWLAVVGVLYLVLGGGYAAAWFFAPVPAAFAFVAITWLHWGQGDLYPLLDFLDVDYLDTRPRRAATVLIRGGLPMLVPLLGFPERYRSVVDAFAAPFGGSVGDLAVFDPRVRLWLGVAFAAATVAVLAAGRRRTHSPGAWRVDAAETLLLWVFFFVVPPVFAVGVYFCVWHSVRHVARAIAVDGSVHPSLRAGDILGPLARFGVEAAPMTAAALALGGVLWWAVPNPPTTLESGAALYLVLIAVLTLPHVAVVTWMDRVQGVL
What is the function of this protein?
Appears to partially substitute for Brp function in retinal biosynthesis during bacteriorhodopsin production.  Probably catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
What are the official names of this protein?
Probable beta-carotene 15,15'-dioxygenase Blh, Brp-like homolog.
What is the protein family that this protein belongs to?
Belongs to the Brp/Blh beta-carotene diooxygenase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BETI_BRUSI
Sequence: MPKIGMEPLRRRELIDAAIRTIGQRGSLDVTVAQIAHEAGVSPALAHHYFGGKDKLILATMRHLLRELGRDLNAAIKQANTPHERIAAIIAVNFSAAQFAQETIAAWLTFYVHAQQSDDIKRLLRIYARRLHSNLVFALEQLTSRARANRIAEGAGAMIDGLYIRHALGADVPDAASAIALVEDYIAIQLSGQPSAEN
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: ITPA_CAEEL
Sequence: MSLRKINFVTGNVKKLEEVKAILKNFEVSNVDVDLDEFQGEPEFIAERKCREAVEAVKGPVLVEDTSLCFNAMGGLPGPYIKWFLKNLKPEGLHNMLAGFSDKTAYAQCIFAYTEGLGKPIHVFAGKCPGQIVAPRGDTAFGWDPCFQPDGFKETFGEMDKDVKNEISHRAKALELLKEYFQNN
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUS7_ORYSJ
Sequence: MAAGPAGIVWQTPANPPERQDYIFRDGRRYVRPYYFEFISHVKNRWAGKTIVDLFTDEFKGRPREYYVHAVKCGRLQVDDQMVHADYVVQSSQKISHFLHRHEPPVLGGDITILQNEADVVTVCKPASVPVHPCGQYRKNTVVGILQAEHGLVPLFPVHRLDRLVSGLLIFAKNADKAESFRQQIEASLLQKEYVAKVVGVFPDGEQTVNANVHFNAREGRSTAEVCDGDGKAPIGKQACTKFQRICTDGIHSIVLCKPVTGRTHQIRVHLKHIGYPIANDEVYLSENFSPRSSKGTRINRATTLACSLPSSDPDSCADLGNNDTNEDTEADEEFSIDPMCTNCPNLAPVGYDADEEALWLHCVRYTGPDWSYECPYPDWAFLDNVSRKKLKS
What are the official names of this protein?
RNA pseudouridine synthase 7, RNA pseudouridylate synthase 7, RNA-uridine isomerase 7.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: RPOC_RICPR
Sequence: MSVVNFYGQLSNTQQFDQIRINIASPDQVRSWSFGEVTKPETINYRTFKPEKDGLFCARIFGPVKDYECLCGKYKRMKNRGITCEKCGVEVTVSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTMRDVEKILYFENYVVVDPGLSILQKGELLTEEELQKAKDKYGEDAFTASIGAEVIQQMLKELDFSKLKQELYDELHITSSEVKKKKLVKRLKLVEDFLESENKPEWMIMDVLPVIPPEIRPLVMLDGGRFATSDLNELYRRVINRNNRLKKLIESKAPDIIVRNEKRMLQEAVDALFDNGRRGRAAKNANKRPFKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSKLELYGIATTIKAAKRMVEAEKPEVWDVLEEVIREHPVLLNRAPTLHRLGIQAFEPLLIEGKAIQLHPLVCAAFNADFDGDQMAVHIPLSIEAQLEARVFMMSTNNILSPANGRPIIVPDKDIVLGLYYLTIAFDNEVGEGMMFSDLAEMEHALYNKFITIHTKIKYRRDQLNAEGKMVPVIIDTTYGRLMVGELLPSNPNIEFKFINKQLTKKDISLVIDLVYRHCGQKATVIFADQLMKLGFKYACSSGISFGMDDMVVPESKSTHINETQLEIKEFEQQYSNGLITYGEKYNKVVDAWSRCTDRVANDMMKEIATPPVNDYPNHQKINAIYMMAISGARGSFQQIKQLGGMRGLMTKSNGQIIQTPIISNFKEGLTEFECFNSANGMRKGQIDTALKTASSGYLTRKLVDVAQDCIITEKDCGTDKGIEVKSVIEGGEIIVPLAEKILGRTAAIDIFHPVTNDLILNKGELINESKLEQIESAGLDRIMIKSVLTCESSTGICSICYGRDLATGTLVSEGEAIGVIAAQSIGEPGTQLTMRTFHIGGAATKGAEVSSVEASYDAKVKIISRNVVINSEERKIVMSRNCELLLLDNNGNEKARHKIPYGARLLVDDGDMVIKTQKLAEWDPYTIPIITEKSGKVLFKDMVEGISIRDVTDEATGIPSKVIIESKQYSRGAELRPRIQLLDSKGEVITLSNGLEARYYLPVGAVLSVEDGIQISVGDIIARIPKESTTTKDITGGLPRVAELVEARRPKDHAVIAEVDGRVEFGKDYKSKRRIIIHPIDGTMSIEYMVPKGKHVVVNEGDFVKKGDLLIDGNPVLQDILKVMGVEVLANYIVKEVQAVYRLQGVKIDDKHIEVIIRQMLQKVEVTDSGGTTLLVGEKIDRHEFDEINAKAMKNGLKPAEAQLILQGITKASLQTRSFISAASFQETTRVLTEAAIAGKVDKLRGLKENVIVGRLVPAGTGYFMDKMRKAAVKLDEENV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SEL7_CAEEL
Sequence: MAQPNQPTPQFQMAQIPLAAFFDNNESKTMLNSMNLRLNDMDLKLSLILELLATRLPDQRLPSIFTSPPQTVISEAPPQSFTPSATNSTSDKTSSSLKTELKTEDSDGDLDMEGEEDTEELFDNESQPSQRNQSPKETEVEDEKVLADGPFPEGAVKRAAEKAARSFQSTQPKVFAWQILRESVTDDELRNVQISLRTFHGETADHLLGRQLPKIRLVVEATMKYFKWDLLSTESQLSKAKLILSHLKNNAKVRNWTLREGRPNRVAPATPPVNVDLVWKRYLALLGPAGFTGILPNLPQNLCNGGTQSPSIPQIDPSLFKVDA
What is the function of this protein?
Putative transcription factor (PubMed:19500563).  Positive regulator of the lin-12/Notch signaling pathway (PubMed:15020414).  Binds to specific DNA sequences in regulatory elements (PubMed:19500563).  Involved in cell fate decisions that require cell-cell interactions, such as the anchor cell (AC) / ventral uterine (VU) precursor cell fate decision (PubMed:15020414).  Heterochronic protein which controls the choice of stage specific cell fates, including the larval L3 stage-specific fate of seam cells (PubMed:19500563).  Involved in regulating the temporal expression pattern of hunchback-like protein hbl-1, thereby playing a role in the progression between larval stages L2 and L3 (PubMed:19500563).
What are the official names of this protein?
Putative transcription factor sel-7, Suppressor/enhancer of lin-12 protein 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: CORA_WOLSU
Sequence: MMNIFTKREGLVLRESFSSIQTPHSTSNVLWIDLLHPSPAEVSYISQIFHLDIPTKEEREEIEQSARYWEDSESITINTYFLVSLFASTNKKDLHNETVTFLLCKDILFTIRYGEFRTFDEIQNKVLASPKNFQNGYDILSKIFEIRVEQDADMLENTAKDTRGLRSGVFGNQFGYDELLENLSRLQELNMRIRDSLFDKRRAITALLKTDKADIEVKKNLTIVLKDLNSLVEFTTVNMNALDNIQSLFSSQINIEQNKTIKIFTVATVGFMPPTLIASIYGMNFDVMPELHWEWGYPLTLCLMVISTMIPILYFKKKKWL
What is the function of this protein?
Mediates influx of magnesium ions (By similarity).  Alternates between open and closed states.  Activated by low cytoplasmic Mg(2+) levels.  Inactive when cytoplasmic Mg(2+) levels are high (By similarity).
What are the official names of this protein?
Magnesium transport protein CorA.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TEX50_HUMAN
Sequence: MSNQRLPLIFSLLFICFFGESFCICDGTVWTKVGWEILPEEVHYWKVKGSPSHCLPYLLDKLCCDFANMDIFQGCLYLIYNLLQAVFFVLFVLSVHYLWKKWKKHQKKLKKQASLEKPGNDLESPLINNIDQTLHRVATTASVIYKIWEHRSHHPSSKKIKHCKLKKKSKEEGARRY
What are the official names of this protein?
Testis-expressed protein 50.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: YL18_CAEEL
Sequence: MQNDRSRWKTEGHSSEVHEDFLRNSVQRRNQLEKILFSYNNLHRLDPSYGEIVQRAFESNDPIALWNFENEVLLNSKDVDDLMQQQFAAPVQNNQCPNPYQNCGYQNNLVSTLDASFKVHPFAQHGNYMPPPAQFASNPNVFPQPVPPYTMDLAASNSGFAHPQIVNQPMHPHVPVGSQNYNPPQFVPAPPTMMPVGAVMVSQGSYSMSPPQIDTSKPPSGYGFSSPIFPSPSYSQYSGPPANEGFPDIIYDNNGVAYCRVVSAPVCVVSMSQSGSSVCSSQSFSSGQSDISMSSRPPINGSSVGNGSLSPMTDSVREESEDEDYGTLTPVGQQDCDLDSVDTESVANEPEPYSSTMSEMPPLDDVDDIMENLDLSKTLIEPETLEHSDNMSVVEIKSEPVSEMTTDSLIVDDDRDTSISEIIKYLDTSDDVLESWQEATGRKKCFVPQKTQKLVYPLPLSKVEKPLQKCQQTLAASTIDEDSKEASTIALPDARKKLTKKEKRLMAAQKANQLETDDDVLEAAYRERQKHVEQAGGDYSSSGQKDQKKKRGKRPVSNPPPSLISPQILHAVQMAIANRAKKISESGRPIFHENFSYQKFYETVDTFVKTWEENSNEMNKVLQFIEKRILAFKMVQRPQSLSRITIYEQLQLNLPPAILPELCFLAGLTSDSTDKLEYYEEIFFNLF
What are the official names of this protein?
Uncharacterized protein C02F12.8.
Protein: RLMN_BDEBA
Sequence: MEANAGSTLAPVNYSDDNVAKPLENQPVNFYSLTLEDLKAYIKSKGKEQFRAQQIFKWVYEQRVTDPEQMTNLSKEFRQDLPSMLSFDLPPVLQHLKSVDGTQKFLFDMKDGMSVEAVVIPSEDRLTLCISSEVGCNMACKFCFTGKQKLKRRLRTEDIVGQFMQVHDRLAEGQRITNIVFMGMGEPLDNPEAVFKTIDVIHSPWGINLSRKKITVSTSGIVPEMWRVADAKVRLAVSLNGPNDEIRSQVMPINKRWDTKALLEACKEHYRVSKDKITFEYVLLKGITDQLEHARQLVKLVKDVPCKINIIPFNEHPGSGYERPDDDTIQAFHTELMNLGAHVLLRRSMGRDIFAACGQLTTVKERPQTMDISNSRLAGLPKYKRELLAAQEAEQNNQH
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VA0E2_ARATH
Sequence: MAFVVTSLIFAVVGIIASICTRICFNKGPSTNLLHLTLVITATVCCWMMWAIVYIAQMNPLIVPILSEVE
What is the function of this protein?
Subunit of the integral membrane V0 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit e2, V-ATPase subunit e2, Vacuolar H(+)-ATPase subunit e isoform 2, Vacuolar proton pump subunit e2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase e1/e2 subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: NRDR_XANOR
Sequence: MHCPFCQHSDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVAEEQIEAAVRSVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEVALERAGKPGKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CX6B1_CARSF
Sequence: MAEDIKTKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPISWVSTWDDRRAEGTFPGKI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6B family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: GSM1_LODEL
Sequence: MTKRLTPQEKLSRKPASRACTFCHQKHLQCSNERPCKNCVKRNIADQCQDITRKRVKYLTGANSKAVAAATTPEATTTTPKRKQKRSVKGSPSISFPSSSISPINTSTFDTNGHPNGHPNDLLRQSLEASQAGQAQAPSLLEIQGPFPQMQTLQPTHTVASETSSSYSQVQPQHHPESSVPPSAPPESVDQLQQLMMHDSAYFNTNNVALNPTNVLEADPFDGHTNTMLNTTTDVLNKLLNDHYEIDNILQPPDDALLVDQQQSSSEATGTSASKAVPMGPSHSNTHFSSNYLNEEYLMLGDILLQSKPTSPSPSNTSASEYNMLSPSYTQNIDFDNIHLSKRKVVQKLKDSRPFISLGFPKDSSLSLDNLNNMAHQTDNLLDNNVSSRGNNNTSNQKLQSAIASKTSKTNPIINFATKYSTEYVSPLSTHQIYQTVSDIYSKDVLNYEYPNSYHALTHFLKTRFSGNNLPHEEKARKRQNLLVILKLIASYRPTFISAHKSLLKPQDLLFLEMSFQRCLIDYEKLSQLNSSPTIIWRRTGEIVSITDDLLSLLGYKLLDILSKRTFIMEIMYDDESIVKYFQLFKSVAVGNLHSSINTKVKLIKNGGAVPGGGTSNGKYNYNNNYNHNYSHNNNNNNNSNNSNNNGMSTGAGNSGDGDGLENNVGTNSYIEFCSVWTVKRDLFDIPMLIIGQFLPILPAGDGVRMY
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.
What are the official names of this protein?
Glucose starvation modulator protein 1.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUGC_MYCTU
Sequence: MAEIVLDHVNKSYPDGHTAVRDLNLTIADGEFLILVGPSGCGKTTTLNMIAGLEDISSGELRIAGERVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLTLAKMRKADIAQKVSETAKILDLTNLLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVQMRGEIAQLQRRLGTTTVYVTHDQTEAMTLGDRVVVMYGGIAQQIGTPEELYERPANLFVAGFIGSPAMNFFPARLTAIGLTLPFGEVTLAPEVQGVIAAHPKPENVIVGVRPEHIQDAALIDAYQRIRALTFQVKVNLVESLGADKYLYFTTESPAVHSVQLDELAEVEGESALHENQFVARVPAESKVAIGQSVELAFDTARLAVFDADSGANLTIPHRA
What is the function of this protein?
Part of the ABC transporter complex LpqY-SugA-SugB-SugC, which is highly specific for uptake of trehalose.  Involved in the recycling of extracellular trehalose released from trehalose-containing molecules synthesized by M. tuberculosis.  Trehalose uptake is essential for virulence (PubMed:21118978).  Responsible for energy coupling to the transport system (PubMed:32092417).
What are the official names of this protein?
Trehalose import ATP-binding protein SugC, MtbSugC, Nucleotide-binding domain of SugABC transporter, NBD of SugABC transporter, SugABC transporter ATPase SugC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: 5HT1A_XENLA
Sequence: MDASNNTTSWNILQRGRMGPSWRRCPVSYQIIASLFLGRSFSAGIFGNACVIAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAAQNQVLNKWTLGQVTCDIFISLDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAVLISITWIVGFSISIPPMLGWRTPEDRSDPNACRISEDPGYTIYSTFGAFYIPLILMLVLYGKIFKAARFRIRKTVKKAEKKKVADTCLSVSQQSPKEKQRGAQQELEEVGGAQAQRCVNGAIRHGEEGAVLEIIEVHHYVNSKCHLHCKPVPPPEQLPPALKNDRATEAKRKVALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCETCHMPHLLFDIITWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCKFCRQ
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various drugs and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores.  Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism.  Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity and behavior.  Activation of the receptor may play a role in the exit from G0 phase and in promoting DNA synthesis.
What are the official names of this protein?
5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, x5-HT1A, Serotonin receptor 1A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: PYR4_MICDP
Sequence: MPITTAASRLGTSAFSNAAPIELRSNTNKAEIAQVIAAIYRQVLGNDYVLQSERLKGLESLLTNGNITVQEFVRQLAKSNLYKSKFFSNNFHSRVTELNFKHLLGRAPYDESEIIYHLDLYQTKGYEADIDSYIDSAEYQTNFADNIVPYYRGFNNQLGQKTVGFTRIFQLYRGYATSDRSQIPGASARLANELARNSASTVIAPAGSNNGFAYRASVKGKTPSTAFQGSQAFGSGRLYRVEVAAISQPAIQVRRINKRSIHRRTIQLFPTSSTSQWQIASVTPL
What is the function of this protein?
Rod linker protein, associated with phycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome 31.6 kDa linker polypeptide, phycocyanin-associated, rod, L-31.6/R.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with phycocyanin.
Protein: IDI_CERS5
Sequence: MPEMVPAWVDGRLMPVEKLEAHQRGLRHKAISVFVMAGESVLIQRRAAGKYHTPGLWANTCCTHPRWGEAAADCAVRRLREELGITGLVTVFADQVEYRADVGSGLIEHEVVDIFVAEAPQDLPVAPDPEEVWETRWVDLHDLAREVEEHPERFTPWLRIYLADHMERIFGKLRVVQ
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYG_CHLTE
Sequence: MNKLVSLAKRRGFIFPSSEIYGGLSSCFDYGPLGSEMKKNIKDLWWNAMTRRHQNIVGIDASIMMNPTVWEASGHVASFNDPMIDDKTTKRRYRADHLIENHIEKLHRDGKEAEAAAIKVAYEAAGGTEDPNRTLYNIIIEAGIKAPDTGSADWTEVRQFNLMFQCNMGAVADSAGVVYLRPETAQGIFVNFHNVREASRMKVPFGIAQIGKAFRNEIVKGNFIFRMVEFEQMEMQYFVKPGTQLEAFEAWREERFRWYSETLGMSKEKLHWYKHDKLAHYADLAYDIKFEFPFGIEEIEGIHSRTDFDLSQHQKYSGKSMEYIDQTTNERYIPYVVETSSGCDRTFLALLSDAYQEDVVDGEPRVMLKLAPKVAPVKAAVLPLMKKGEMGEKAAQLCRDLSESFMVQYDDAASIGKRYRRQDEIGTPFCFTVDHDTLENGTITVRYRDTAAQERINMSKAAEFLATKLM
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTR1L_RAT
Sequence: YCYICHSLQYNADLQPANTCIYLVVTWVMTVLDVLPNVYIGTIEYDPRTYTCYFNYVNNPAFTVTIVCIHFVLPLIIVGYCYTKIWIKVLADRDPAGQNPDNQFAEVRNFLTMFVIFLL
What is the function of this protein?
Does not bind melatonin.
What are the official names of this protein?
Melatonin-related receptor, G protein-coupled receptor 50, H9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YNFB_ECO24
Sequence: MKITLSKRIGLLAFLLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: RGS16_PIG
Sequence: MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGSDPASVGKFEWGSKHSKDGRNFSEDVLGWRESFDLLLSSKNGVAAFHTFLKTEFSEENLEFWLACEEFKKLRSATKLASRAHRIFEEFIRSEAPKEVNLDHETRELTRTNLQAATATCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLAAQAASASPSSGSPAEPSHT
What is the function of this protein?
(Microbial infection) Gets inactivated and/or degraded by porcine circovirus 2 ORF3 protein, leading to enhanced expression of IL-6 and IL-8 in infected lymphocytes.  This would explain chronic inflammatory response of PCV2 infected pigs.
What are the official names of this protein?
Regulator of G-protein signaling 16, poRGS16.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: HELQ_MOUSE
Sequence: MEDGCPRIRRRVSVRKRNRGNLENLRASPTPAELQPAEDTEDEAAAGSRRRKTGSPEHAQENDSEEDMFGDYDSFTESSFLAHVDDLEQRYMQLPECGDRDADSGTKDLCSAGLKNNLRVTTVINLTDPETSEHGQKQSHLDVPAEPEPGSDLSFDVPSSQILYFENPQNSPEALGDPCTKKTNGDPQKSSHEELVSSHTEQPEPNNDFSNVRAASESSRRKSLKDHLKSTMAGNARAQTPAFPRSKHLREALLSEEISVAKKAIESPSDDLGPFYSLPSKVRDLYVQLKGIKKLYDWQHTCLTLRSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLMILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKAHSLVNALIETSRLSTLGLVVVDELHMIGEGSRGAILEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSQAADGMTFSRLLSYKYSEALKKMDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSKDYLNHREKEKCEVIKSLRNIGNGKVCPVLKRTVPFGIAYHHSGLTSEERKLLEEAYSTGVLCLLTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMVGRAGRAGIDTAGESILLLQEKDKQQVLELISGPLETCCSHLVEEFTKGIQALFLSLIGLKIAASLGDIYQFMSGTFFGVQQKILLKEKSLWEITVDALEHLTEKGLLQKDSCGDNEGLECHFRITKLGQASFKGAIDLAYCDTLYRDLKKGLEGLVLESLLHLIYLTTPYDLAAQSEPDWMVYFKQFGQLSPTEQNVAALLGVSESFIGKKAAGQAVRKKVDKNVVNRLYLSFVLYSLLKETNVWSVSEKFNLPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYNAGYRSIMHLANANPEVLVKTIDHLSRRQARQIVSSAKMLLHEKAEALQGEAEELLRLPADLPGLGGPSSERAGSHAGDVTLS
What is the function of this protein?
Single-stranded 3'-5' DNA helicase that plays a key role in homology-driven double-strand break (DSB) repair (PubMed:24005329, PubMed:24005041).  Involved in different DSB repair mechanisms that are guided by annealing of extensive stretches of complementary bases at break ends, such as microhomology-mediated end-joining (MMEJ), single-strand annealing (SSA) or synthesis-dependent strand annealing (SDSA) (By similarity).  Possesses both DNA unwinding and annealing activities (By similarity).  Forms a complex with RAD51, stimulating HELQ DNA helicase activity and ability to unwing DNA (By similarity).  Efficiently unwinds substrates containing 3' overhangs or a D-loop (By similarity).  In contrast, interaction with the replication protein A (RPA/RP-A) complex inhibits DNA unwinding by HELQ but strongly stimulates DNA strand annealing (By similarity).  Triggers displacement of RPA from single-stranded DNA to facilitate annealing of complementary sequences (By similarity).
What are the official names of this protein?
Helicase POLQ-like, Mus308-like helicase, POLQ-like helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of DNA damage; localizes to damaged replication forks.