PharMolix/UniProtQA huggingface dataset:
Protein: AROD_ECOLI
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDILEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids (AroAA).  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.  The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsilon-amino group of a Lys-170 at the active site.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: FISL_NEIMA
Sequence: MPHTLPDISQCIRQNLEQYFKDLNGTEPCGVYDMVLHQVEKPLLVCVMEQCGGNQSKASVMLGLNRNTLRKKLIQHGLL
What are the official names of this protein?
Putative Fis-like DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: RL31B_DICNV
Sequence: MKKDIHPAYRPVVFYDASAEFKILTRSTVETKETIQWEDGNEYPLVRIDVSSKSHPFYTGKQNIVDTAGRVDRFRRKYGKKN
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: M10_ARATH
Sequence: MGNLMSLVLVALLFSLSLAVIADTSNDATHVKEEVKPSTEATDAIEAEVEVNDAVVEPQQGLPGGGCRFGCCGGYWWNGLCIYCCRSQAEANEVVKTVEPQKEEAKP
What is the function of this protein?
May be involved in the acquisition of desiccation tolerance during late phase of embryogenesis.
What are the official names of this protein?
Late embryogenesis abundant protein M10, AtM10.
Protein: ADA2B_HORSE
Sequence: AIAAVITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVTRALEYNTKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSHLRGPRAKGGPGGGGSKQPHPVPAGASASAKLPTVASCLAAAGEANGHSEPTGEKEAETPEDSGTPALPSSWPALPSSGQDQKEGVCGASLEEEAEEEEEEEEEEEEGEEECEPQALPASPASACSPPLQQPQGSRVLATLRGQVLLGRGVATAGAQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICP
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Alpha-2B adrenergic receptor, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor, Alpha-2BAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Interaction with RAB26, GGA1, GGA2 and GGA3 mediates transport from the Golgi to the cell membrane.
Protein: SCAA2_MESMA
Sequence: VKDGYIVDDKNCAYFCGRNAYCDDECEKNGAESGYCQWAGVYGNACWCYKLPDKVPIRVPGRCNG
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission (By similarity).  In vivo, shows analgesic activity (ED(50) is 1. 42 mg/kg) and antitumor activity against Ehrlich ascites tumor and S-180 fibrosarcoma models (PubMed:24269605).
What are the official names of this protein?
Neurotoxin BmK AGAP-SYPU2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXH_ECODH
Sequence: MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1252_METJA
Sequence: MCKAFCSCYSYHYHHREKMGIKEYYDKLAKSYDKLYKNKYMRIVEREIIQKEIKDGDFVLDIGCGTGEQLKILNNAVGLDISLEMAKIAKNKTNKPVVVANAEFLPFKNKSFDKAISFFGALNHCNLKRALREVNRVLKDDGIFIFTVANIYDIKWIIKNILKGNFKKVKNAMKKRKGTITKVIDGEKIKVKTRFYDFKEVEDALKKEGFEVVYTFGTNITNSPLDKFIYKSFLKNFASYIGFVAKKVKNR
What are the official names of this protein?
Uncharacterized protein MJ1252.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0638 and MJ1123 and M.tuberculosis Rv2003c.
Protein: TNF18_HUMAN
Sequence: MCLSHLENMPLSHSRTQGAQRSSWKLWLFCSIVMLLFLCSFSWLIFIFLQLETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFIS
What is the function of this protein?
Cytokine that binds to TNFRSF18/AITR/GITR.  Regulates T-cell responses.  Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation.  Important for interactions between activated T-lymphocytes and endothelial cells.  Mediates activation of NF-kappa-B.  Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569).  Promotes leukocyte adhesion to endothelial cells (PubMed:23892569).  Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, hGITRL.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: AMN1_RAT
Sequence: MPSSRVVSQLLELCLRCLIINISRYISDIKYLPPNIKDRLIKIMSMRGRITDSNINEVLHPEVQRLDLRSCNISDVALQHLCKCRKLKALNLKSCREHRNSITSEGIKAVASSCSDLHEISLKGCCSVTDEGVLALALNCQLLKIIDLGGCLSITDESLHALGKNCPFLQCVDFSTTQVSDNGVVALVSGPCAKQLEEINMGYCINLTDKAVEAALTACPQICILLFHGCPLITDHSREVLEQLIGSRKLKQVTWSVY
What are the official names of this protein?
Protein AMN1 homolog.
What is the protein family that this protein belongs to?
Belongs to the AMN1 family.
Protein: YLA2_LACAI
Sequence: MTKHYKIIGLRILSWVITITGLIIFIGNVHEYGLHFTYNQVLAIIIVILLLVTTMYFSVTPKLLKWNEKYELVWWLCYLCAPIYLFLTNLYNSTDLGYTIKFWLFFGGGAALIIISKYILKNKK
What are the official names of this protein?
Uncharacterized 14.5 kDa protein in laf 3'region.
Protein: PGK_YARLI
Sequence: MSLTNKLSIKDLDLKNKRVFIRVDFNVPLDGTTITNNQRIVAALPSIKYAIDQGAKAVILASHLGRPNGQRVEKYSLKPVQAELSKLLGKPVTFLDDCVGPKVEEEVSKAKDGEVILLENLRFHPEEEGSHKDADGKKIKADPAKVEEFRKSLTSLADVYVNDAFGTAHRAHSSMVGIELPQRAAGFLVAKELEFFAKALEHPERPFLAILGGAKVSDKIQLIDNLLDKVNALIIGGGMAFTFKKTLENVKIGNSLFDEDGSKIVAGLVEKAKKNNVKLVFPVDYVTADKFSKDAKVGHATDAEGIPDGWQGLDCGPKSIEEFQKVIGESKTILWNGPPGVFEFDNFAKGTKAVLDACVKAVDNGATVIIGGGDTATVAKKYGAEDKLSHVSTGGGASLELLEGKTLPGVAALSEKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP107_RAT
Sequence: MAVRVPLGCTGSFCPRLLPLLALLELLVDPSLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNISSLSVNEPEGVKDKDTEIGFSLDRTKNDGFSSYLDEDVNYCILKKKSMSSVTLLILDISGSGVKVRSPPEAGKQLPEIVFSKDEKVPSRSQEPAVSSNPKDSKVQRTPDGSKAQRSTVDSKTIAEKFFSIHKNDGAVSFQFFFNISTSDQEGLYSLYFHKCPSSKLRSGEQVSFSLNIDITEKNPDSYLSAGEIPLPKLYVSMALLFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKFAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEEDDLEMESVVTTSGVMENMKKVKKVSNGAVEPQGSWEGTA
What is the function of this protein?
Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor (PubMed:22933024, PubMed:26561648).  Involved in blood sugar regulation through the induction of glucagon in response to low glucose (PubMed:26561648).
What are the official names of this protein?
Protein GPR107.
What is the protein family that this protein belongs to?
Belongs to the LU7TM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: IPI1_BPT4
Sequence: MKTFKEFTSTTTPVSTITEATLTSEVIKANKGREGKPMISLVDGEEIKGTVYLGDGWSAKKDGATIVISPAEETALFKAKHISAAHLKIIAKNLL
What is the function of this protein?
Internal protein I is one of four proteins in a complex that functions in bacteriophage head maturation.
What are the official names of this protein?
Internal protein I, IpI.
Protein: RSMG_SHESW
Sequence: MLSAQLEAYLAEINLSATAEQKKQLIDFVGMLNKWNKAYNLTSVRDPEAMLVRHIMDSLVVSKHLQGERFIDVGTGPGLPGIPLAIMNPNKTFVLLDSLGKRIRFQKQVAFELGIRNISSVESRVEAYQAEQQFDGVLSRAFASIQDMLSWCHHLPAENGLFYALKGQLNDEELQQMPSGFVIKEIIELKVPKLDEQRHLLKIIKE
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y701_STAEQ
Sequence: MSNQSKLNSAAYDQLNKDADRILHLIKVQMDNLTLPSCPLYEEVLDTQMFGLQKEVDFAVQLGLVDKEDGKQLMLRLEKELSKLHEAFTNV
What are the official names of this protein?
UPF0358 protein SERP0701.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: RIR1_BUCAP
Sequence: MKNSLFVTKRNGKKEKINLDKIHKVLNWAAKGLENISVSQVELRSRIQFYNNISTVNIHETIIKAAADLISENTPDYQYMAARLAIFHLRKKAYGQFEPPNLYYHVKKMVQLGKYDEKLLQNYSFEEYVEMNSFVDHRRDMNFSYAAVKQLEAKYLLQNRVTGQIYESAQFLYILISACLFSKYEKKVRMNYIQRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECADNLNSINATTSAIVKYVSQRAGIGINAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGGVRGGAATVFYPIWHLEIESLLVLKNNRGIEENRVRHLDYAVQINKLMYQRMLLGQKITLFSPSDVPKLYEFFFSDQKKFKEIYIKYEKNRNIRKKSINAIDLFCLIMRERASTGRIYIQHVDHCNSHSAFNSKLATIRQSNLCLEITLPTKPLNNIDDKNGEIALCTLSALNLGLINDLHDLKELSTLSVRALDEILEYQNYPVVCAKKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAKNLTHKTFEAIQYYLLKASCELAKEKGSCSLFNQTNYYLGKFPIDTYKKDIDSICNEPLHLNWNLLRKKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRGFISIKSSKDGMLRQVVPEYKKLKSEYELLWEIPNNIGYLELVAIMQKFVDQSISANTNYDPKRFLNEKIPMKQLIYDLLVAYKLGIKTLYYQNTRDGAEDNQNLNKSIENIKEDNCTSGSCTI
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit alpha, Ribonucleotide reductase.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: RUTD_ECO27
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLDQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTVLVSVNGWLRINAHTRRCFQVREQLLHSGGAQAWVEALPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: NEMF_MOUSE
Sequence: MKSRFSTVDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYLILNILRFRTDEADDVKFAVRERYPIDHARAAEPLLTLERLTEVIAAAPKGEVLKRVLNPLLPYGPALIEHCLIESGFSGNAKVDEKLESKDIEKILVCVQRAEDYLRKTSNFNGKGYIIQKREAKPSLDADKPAEDILTYEEFHPFLFSQHLQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGVIVKEAQAQGDPVACAIKELKLQTNHVTMLLRNPYLLSEEEDGDGDASIENSDAEAPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQRTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHRGERKVRVQDEDMETLTSCTSELMAEEMEQLEGGDSSEEETEELHGMPGDVELMTQVDQEDIAVHSGRDELSSEDGEAKAVTKDQEPIGEMKEEEEDTFEYPDTTIDLSHLQSQRPLQKLAPREESLNSNDSKSQGRRHLSAKERREMKKKKLPCESGDLEVIEEKDKERESAVHTEAYQNTSKNVAAGQPMKRGQKSKMKKMKEKYKDQDDEDRELIMKLLASAGSNKEEKGKKGKKGKPKDEPVKKPPQKPRGGQRVLDVVKEPPSLQVLAHDLQDLAVDDPHDDKEEHDLDQQGNEENLFDSLTGQPHPEDVLMFAIPICAPYTIMTNYKYKVKLTPGVQKKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLHVKRK
What is the function of this protein?
As part of the ribosome quality control complex (RQC), a ribosome-associated complex, mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes as well as their ubiquitin-mediated proteasomal degradation.  Thereby, frees ribosomes from the stalled translation complex and prevents the accumulation of nascent polypeptide chains that are potentially toxic for the cell.  It is responsible both for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety and the recruitment of the E3 ubiquitin-protein ligase LTN1 to the ribosome quality control complex.  May indirectly play a role in nuclear export.
What are the official names of this protein?
Ribosome quality control complex subunit NEMF, Nuclear export mediator factor, Serologically defined colon cancer antigen 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NEMF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IPI1_PICGU
Sequence: MAKKKTEKQKDFVKPKLRVGKTKAKPDNHTDTSFVAKSISLPNQSIAQKSDKNDEKDFLHQLSLTKHHSSTTRKEVLKSISSQLPSNPSLYKQILSSIMPLVHDSSQQVREEVASLLQKCAETQSGLLDLHITSVILFVHSAMSHIQPDIRSSSTKFLDIVLQHASEAVARSYFVKTLRSFFTIMSWNLRDDKKSLSLAVTTSSSIGGTSKKARVGHLAVLLRFLESTLFQKTAETTSVPINYIHPQTSHYMLPTNPHPYASLKLFTQETPQADDMFSLASLESLATDDLDTRRKIVHDVFQEPLRKNLTNLVKEGGEVGREAKSCLGVLDRLESS
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS15_BURCJ
Sequence: MSVADIKKSEVVAQFARGTNDTGSPEVQVALLTARIVELTGHFKTHAKDHHSRRGLLRMVSRRRKLLDYLKGKDADRYRALIEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MURA1_BACAN
Sequence: MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S1PBP_BOVIN
Sequence: MMCSLVPSEQSSGTSLLPKDNAPFSWSSLDEDELDDSLLELSDGEDDGHFSFTEEQIQELLKDDDLSNEHFPWGGGLPSDDSRNVEKGEKGSQIPLDTPQEKDSPYNMGPEAETPDTFKLPQLTTSVGHGPTPAKSLNRRFALEKNLIKVTVAPFDPTVCDVALDKDKTYVSEVTSRVTEKPSSLGEEMREDDLSPNESTLCTESEGISPDNSASDGPPLPSSNSNFQHTVSDKNMSDSKKATPVFSQILDHSETPNTGSSRRNGSYKSSFEMKLPVSSSSSKDVLDKDSGKLKVHEKRLGKVIPVLQAKTRTNVPTFSPSDLEKQKQSYLRNVIAHIEDPVDSNQGTLGELCALMDQVHHMHNQKWQHPSDLTRRNYARFRQKSLQRYSLTQWVDRNKRSHHRFQRLPDFPYGPFVSSHQQ
What are the official names of this protein?
S100P-binding protein.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with S100P in the nucleus.
Protein: GCH1_BACC4
Sequence: MAKVNLEQIEHAVRLILEAIGDDPNREGVLDTPKRVAKMYAEVFSGMHEDPKEHLHKVFGEDHEELVLVKDIPFYSMCEHHLVPFYGVAHVAYIPQGGKVTGLSKLARTVDTIARRPQLQERITSTVANSIMEVLEPHGVMVVVEAEHMCMTMRGVKKPGAKTVTTAVRGVLENDAAARSEILSFIKTK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RFTN2_PONAB
Sequence: MGCGLRKLEDPDDSSPGKIFSTLKRPQVETKTEFAYEYVLLDFTLQASSNPEVIKINSILDIVTKVEDYYLKGYIVGAIHPVIQPVGQRKHLPASCLYRVVLSRLKLSPKNSAAPSGQRRPRLVIEECPLTSEAQTNDAAKELIEKINFAAKRGMKFVGFISQPYSPYKFCNGTNHDGDIESMLHVRHSSDENCRSWNEGTLSGQSSESGIEEELHHESGQYPMEQNGSPSSSKSRKGEASDNKLYTVFNAFDDDSTSWTYQEGILSMKVTRKGSVISTLDADWLELTTFYYKQGLSLIDSFVFWETSKGEHLPKSLEGFFIYEEEGSGVPGSSRKGNDAIVVEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPVLRHDSEGNLATKQIVFLQRPVMWNSAAQTTDKKASRRIKGEDKNKATSRSIGLDTTTPQPAESRHPPEECRLSPSRECWTKEGRLAQHNSFSGFSSSDSVLRELDDGQFDQEDGVTQVTCM
What is the function of this protein?
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production.  May regulate B-cell antigen receptor mediated-signaling.
What are the official names of this protein?
Raftlin-2, Raft-linking protein 2.
What is the protein family that this protein belongs to?
Belongs to the raftlin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYK_METMP
Sequence: MHWADATSEKIMKKRNAEEYVVSSGITPSGHIHIGNARETLTADAVYKGMLKKGAEAKLIFIADDYDPLRKLYPFLPKEFEKYIGMPLSEIPCPQGCCKSYADHFLMPFLNSLEDLGVEITTHRANECYKAGMYNDAIITALENRLKIKELLDSYRKEPLADDWYPLNVVCEKCGKMHETKVINYNSEDKTITYVCKCGFENTVKPFNGIGKLPWRVDWPARWNIFGVTAEPMGKDHAASGGSYDTGIKIARQIFNYQAPEKMVYEWIQLKVGDKAMPMSSSSGVVFAVKDWTEICHPEVLRFLILKGKPTKHIDFDLKAISNLVDDYDELERKYFELIEKQKTEELNDNENEKISLYELVTPKIPERLPLQVAYRFCSIIAQIALDKETQKIDMERVFDILGRNGYNPAEFSEYDKSRLEKRLYMSKKWASDYGENLEINDLDQAKEQYETLSEEQKAWLKAFSKEVENIEIDANTIHELMYETATKLNLAPKEAFVASYKILLGKNYGPKLGSFLASLKKEFVIGRFNLTE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGTL1_CLOP1
Sequence: MKIRENIEIFERIKLNKVAKFSDESRGRERLEEPDEIRTCFMVDRDRIIHSKSFRRLKRKTQVFIRTYGDHYRTRLVHTLEVSQVARTIGVALSLNEYLIEAIALGHDLGHAAFAHIGEDILNDFLPGGFKHNEQSVRVAKKIEKNGLGLNLTKEVLDGILNHSGFSNVSKVAGTFEGQVVRFADKIAYVNHDIDDSIRAGILKEEDLPKNIIEILGASGSERIDTLVKDCVFNTIDNIDKGEPRVSLSNEIGDAFIQLRKFLFDNIYLGKYLEDERKKAEFVLSKVIEYYYKNWGEMPELYKNICEEEGIHRGVTDYVAGMTDDYCTNEFNKIYIPKFVMY
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: CYB_NEUGI
Sequence: MTNIRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDSDKIPFHPYYTIKDILGILILILALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILVLALMPFLHTSKQRSMMFRPISQCLFWVLVADLLTLTWIGGQPVEHPFVIIGQLASILYFSLILILMPLASLMENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSRA_BRUMB
Sequence: MSFFDSYRKKMQMPSKEEVLPGRVQPIPTAAAHFVSGHPLKGPWPDGMKQVLFGMGCFWGAERLFWQVPGVYVTAVGYAGGITPNPTYEETCTGLTGHAEVVLVVYDPKVVTLNELLALFWEEHDPTQGMRQGNDIGTTYRSVIYTFNAVDRAVAEKSRDAYSQALASRGLGPVTTQITEAPDFYYAEDYHQQYLAKNPDGYCGLRGTGVSCPIPLAH
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: ATPB_SYNAS
Sequence: MNIGRIVQVIGPVIDVVFEEGQLPAILNAITITNPVINDEEDNLIVEVAQHLGDNNVRCIAMDVTDGLVRGMPAKDTGAPITVPVGKECLGRILNVVGKPVDGLGPIEAKNTMPIHREAPSFLEQDTSVHVLETGVKVIDLLVPFPRGGKMGLFGGAGCGKTVVMMEMIHNIAMHHGGISVFAGVGERTREGNDLYREMLESGVIKQAALIYGQMTEPPGARARVSLTALAAAEYFRDVEGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATDLGELQERITSTDKGSITAVQCVYVPADDLTDPAPATTFAHLDGTVVLSRPIAELGIYPAVDPLDSTSRILDPIVLGEEHYKVARAVQVTLQKYKDLQDIIAILGMDELSEEDKLTVNRARKIQRFLSQPFFVAAQFTGVDGKFVSVPDTVRGFKEILEGKYDDLPEQAFYMVGGIEEAVEKAKKYQEQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPO5_METVS
Sequence: MKVSSHEMVPEHEIIPGDEIPFLLEKYGIKIQQFPKLLISDPLVIEVGAKVGDIVKITRKSQTAGETVYFRLVVSNSV
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.