PharMolix/UniProtQA huggingface dataset:
Protein: APOM_PONAB
Sequence: MFHQIWAALLYFYGIILNSIYQCPEHSQLTTLGVDGKEFPEVHLGQWYFIAGAAPTKEELATFDPVDNIIFNMAAGSAPTQLHLRATIRMKDGLCVPRKWIYHLTEGSTDLRTEGRPDMKTELFSSSCPGGIMLNETGQGYQRFLFYNRSPHPPEKCVEEFKSLTSCLDSKAFLLTPRNQEACELSSN
What is the function of this protein?
Probably involved in lipid transport.  Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity).
What are the official names of this protein?
Apolipoprotein M, Apo-M, ApoM.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
What are the subcellular locations of this protein?
Secreted. Note=Present in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL).
Protein: AAS_SHIB3
Sequence: MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGILLGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVAMPDASRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWIDEAEQHDE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPCS2_PLAF7
Sequence: MSGNNVQEEDSTFHVSNLYSETEIKKITQDFISEKIREQNFEEIVKYSNIRIFLSLVLIVIGTYCSIFVQYKKNPVIMIQLLVAFFVVSTTLIIFEYFFFDDVFMILRSNNGSLVKLYCRLDVKKSTLILAYKLNKNVFETSFELKRLYNENGYLMKPYAKNVVMNFLSAHGRTLKLKN
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:30127496).  Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).  Also, regulatory component of the CSP25-plasmepsin PMV complex which cleaves the pentameric localization motif RxLxE/Q/D (termed Plasmodium export element (PEXEL)) located downstream of the N-terminal secretory signal sequence of several proteins (PubMed:30127496).
What are the official names of this protein?
Signal peptidase complex subunit 2, PfSPC25.
What is the protein family that this protein belongs to?
Belongs to the SPCS2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Partially colocalizes with plasmepsin PMV in the endoplasmic reticulum (PubMed:30127496). Partially colocalizes with SEC11/SPC21 in the endoplasmic reticulum (PubMed:30127496).
Protein: TOLB_RICAE
Sequence: MRNIIYFILSLLFSVTSYALETINIEHGRADPTPIAVNKFDADNSAADVLGHDMVKVISNDLKLSGLFRPISAASFIEEKTGIEYKPLFAAWRQINASLLVNGEVKKLESGKFKVSFILWDTLLEKQLAGEMLEVPKNLWRRAAHKIADKIYEKITGDAGYFDTKIVYVSESSSLPKIKRIALMDYDGANNKYLTNGKSLVLTPRFARSADKIFYVSYATKRRVLVYEKDLKTGKESVVGDFPGISFAPRFSPDGRKAVMSIAKNGSTHIYEIDLATKRLHKLTDGFGINTSPSYSPDGKKIVYNSDRNGVPQLYIMNSDGSDVQRISFGGGSYAAPSWSPRGDYIAFTKITKGDGGKTFNIGIMKACPQDDENSEKIITSGYLVESPCWSPNGRVIMFAKGWPSSAKAPGKNKIFAIDLTGHNEREIMTPADASDPEWSGVLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CLPS_GLUOX
Sequence: MGPESPDSIPPHGPGNGDGDQDLDIGVVVRPRTRTRKPSMYKVLMLNDDYTPMEFVVHVLERFFAKTRDEATSIMLQVHQRGVGICGVFTYEVAESKVTQVMDLARQNQHPLQCTIEKD
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: IF2_CLOK5
Sequence: MSKIRIYELAKELNISSKKLITLLLEEFGVEVKNHMSVIEEEDADLIKEFIEENEDKEEYLEDKYKNLPEEKSEKFKKNAGNTVKIADKNKSKQDKAVKDLNEQVSKENHKVEIEDTITVKEFSEKIGKPITEVIKQLIFMGVMAAINQEIDFSTAEKLGEKFDITVLKKKEDIDKGVAEQDEDEDEDTNVEKRPPVVTVMGHVDHGKTSLLDAIRKSKVTATEAGGITQHIGAYTVTINGEKITFLDTPGHEAFTAMRARGAQITDIVILVVAADDGIMPQTAEAINHCKAANVPIVVAINKIDRPGANVDKVKQELTEYQLVPEDWGGDTICIPVSAHTKEGIDTLLEMVLLTAEMQELKANSNRNGKGTVVEAKLDKGRGAVATLLIQNGTLSVGDSIIVGSTYGRIRAMFDDKGNKIKSAGPSIPVEILGLSEVPAAGDRFHQVKDEKTARDIAEKRKQKIREEYLQSTHKVSLEDLYNQIKEGKVKELNIIVKADVQGSIEALKQSLQKLSNEEVKVRVIHGAVGAITETDVTLASASNAIIIGFNVRPDSNAQAAAEKESVDVKTYRVIYNAIEDIKAAMVGMLEPDYKEVILGKAEIRQIYKISNIGTIAGCYVQEGKMVRNCKVRIIRDGIVIFESELASLKRFKDDVKEAAEGYECGLSIEKFNDIKEGDIVEAYDIEEIKKKEL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2465_STAA8
Sequence: MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDSRILEALVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMRKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
What are the official names of this protein?
Uncharacterized hydrolase SAOUHSC_02465.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: LPXK_PSE14
Sequence: MAFTDRLLDAWYKGHPALALLRPLEGLYRRVVEGKRARFLAGEGTIYRAPVPVIVVGNITIGGTGKTPLILWMIEHCRRRGLRVGVVSRGYGAKPPSLPWRVKADQSASEAGDEPLLIVKRSGVPLMIDPDRSRAVQALLAAEPLDLILSDDGLQHYRLARDLELVLIDAARGLGNRRCLPAGPLREPVERLGSVDALLYNGATADRDDGYAFMLKPSALINLRSGERQPVDYFPAGQALHAVAGIGNPQRFFNTLEGLHWRPVAHAFADHAVYSAQALTFTPALPLVMTEKDAVKCRAFAADDWWYLAVDAVPSDAFVDWFDEQLLRLSP
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: SBCC_STAES
Sequence: MKPLHIVMENFGPFIKETIDFEQVETDQLFLISGKTGSGKTMIFDAIVYALYGMASTKTRKEGDLRSHFADGKSPMSVIYQFKVNNQTFKIHREAPFIKEGNITKTQAKLNIYELVDNQFELRESKVNQGNQFIVQLLGVNAEQFRQLFILPQGEFKKFLQSNSKDKQSILRTLFNSERFDEIRHLLLENVKQEKVQIENRYTQIENLWNDIDTFNNDELALYKELESSQTDKMIKKFPQFNDYGCKILKSFEEAKNKITKELDDLNHKYKVNVELSENTKKLKAEKIKFDDLKKEQNYIDKLKQELKMIQESKVLITYFTRLQSLKKDKDELVSLHEQSKLNETNYHNEIKGFQKQLEHLSTRENEITQFNQYLEKNQVFFNQLDKIISSYQQKPVIEEEIKRLYSEYNDLITKKEELTKEMNNKNKDFAIIEHYTEEIYKLKKIIDESERQKKDEKLFDKLQLDKSSYLSKLKEKKEQLNEIESSITNIDATLIDLNDKKDFVNEIKSAMSIGDTCPICGNEIHSLGEHIDFESIAQKNNKIKRLESKKVKIRDEIIKIETRIEELNHRENELNCEKQEKKDISKLQKQLNHLNQLKDEQQSINKLVENFEKQEKEIVNKIHQFDLDLSRKNTQKEKLEIQINDFERHSQFSSVNDFETYYSHAKKQVETYEYENEKTKDKLNELNNKLKIEMNDQKHLTENLTQTSKEINNLELKMEKEMQQLGFESYDQVKSAADLSAQKDEIEREINIYNKNYQSYEIEINRLKELVKGKKLLNLEKLRQSIEKTNLKLDETNSQIATISYKIDNNSNKFNKIKNIIQILDDELKVQKEIFLLSEILAGKNDYKLTLENYVLIYYLEKIIFQANQRLSFMSGNRYQLIRREAISLGLSGLEIDVFDFHSNKSRHISSLSGGETFQASLALALGLSEVVQQESGGITLDSMFIDEGFGTLDQETLETAIDTLINLKSSGRMVGIISHVSELKQRIPLILEVTSNQYESHTQFRKN
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: PROA_ECO81
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSESILNANAQDVADARANGLSEAMLDRLALTPARLKDIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAGK_STAES
Sequence: MRKRARIIYNPTSGKELFKRVLPDALIKLEKAGYETSAYATEKIGDATFEAERALESEYDLLIAAGGDGTLNEVVNGIAEQPNRPKLGVIPMGTVNDFGRALHLPSDIMGAIDVIIDGHTTKVDIGKMNNRYFINLAAGGKLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDVRIEYDDNIFQGEALLFLLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKANLAELGHIMTLASRGEHTKHPKVIYAKAKSINISSFTDMQLNVDGEYGGKLPANFLNLEQHIEIFTPKDVFNEELLENDTITDITPDKQ
What is the function of this protein?
Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid.  Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.
What are the official names of this protein?
Diacylglycerol kinase, DAG kinase, DAGK.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: HHATL_HUMAN
Sequence: MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDVADFEWVMWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALAVMGTMGPWYLLLLLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGSSFTVLRCTSFALESCAHPDRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQVEPVRREGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYSNLVYDWVKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAETHFDRGINDWLCKYVYNHIGGEHSAVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPLARIEASLSVQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLSILFVTYCGVQLVKERERTLALEEEQKQDKEKPE
What is the function of this protein?
Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN.
What are the official names of this protein?
Protein-cysteine N-palmitoyltransferase HHAT-like protein, Glycerol uptake/transporter homolog, Hedgehog acyltransferase-like protein.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. HHAT subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NFUA_PSEU2
Sequence: MTAITITDAAHDYLADLLEKQNTPGIGIRVFITQPGTQYAETCIAYCKPGEEKPEDKAIGLKSFTAWIDGFSEAFLDDAVVDYATDRMGGQLTIKAPNAKVPMVNADSPINERINYYLQTEINPGLASHGGQVTLIDVVEEETKNIAVLQFGGGCQGCGQADVTLKEGIERTLLERIPELSGVRDVTDHTQKENAYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: MURA_HELPG
Sequence: MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSQQEVKIKSLPQVVDIKAMALLLQNLGASLEWLDPNTLQICAKSLHHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILFDKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCAFLQSGGVEIEGVGSSELKIRGVESDALNLKDIQIIPDRIEAGTYLCVGAITNSQLKINRIIPNHLQAITDKLIEIGFSLDIQENSIEIYPAKQRQAFEITTKEYPGFPTDMQAQFMALATQCLGTSVIEETLFENRFMHASELQRLGASISLKTNVATISGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDRGYERLENKINALGAKVVRLKEK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD2_PASMU
Sequence: MAKVFFITGIDTDIGKTIATGWYAKKLMQQGASVITQKMIQTGCRGIAEDLLTHRKIQGIELTEEDKQGITCPYVFDYPCSPHLAAKLEQRTIERKKIETCTALLCEKYDYVLLEGAGGLCVPYNEEETTLDYLCQHQYPVILVTSGKLGSINHTLLSLQVLNSKRVSVHAVIYNLYPETDQVISQETQHFLRRYLEKYSPNTLFEVMDLISV
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD 2, DTB synthetase 2, DTBS 2, Dethiobiotin synthase 2.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCJF_YEREN
Sequence: MSEPLKPRIDFEQPLQPIDEPVLKAAQAFDQHAAENFYPADPELDAENEEGRVEGLVNAALKPKRSLWRKMVTVGIALFGVSVIAQSVQWVNQAWQQQDWIALGATTAGGLIVLAGVGSVVTEWRRLYRLRQRAEERDIARELLVSHGIGQGRAFCEKLARQAGLDQGHPALQRWQASLHETHNDREVVELYAKLVQPSLDNLARAEISRYAAESALMIAVSPLALVDMAFIAWRNIRLINRIAALYGIELGYFSRIRLFRLVLLNIAFAGASELVREVGMDWLSQDLAARLSARAAQGIGAGLLTARLGIKAMELCRPLPWLGDDKPKLGDFRRQLIGQLKNTLPKKDKPAQQ
What are the official names of this protein?
UPF0283 protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCKA_VIBPA
Sequence: MTVMEHTKAATLDLTKHGLHNVKEVVRNPSYELLFEEETRADLTGYERGVVTELGAVAVDTGIFTGRSPKDKYIVKDATTEEHMWWTSDTVKNDNKPITQEVWNDLKELVTNQLSGKRLFVVDGYCGANPDTRLSIRVITEVAWQAHFVKNMFIRPTEEELATFEPDFVVMNGAKCTNPKWEEQGLNSENFTVFNLTERTQLIGGTWYGGEMKKGMFAMMNYFLPLKDIASMHCSANMGKDGDVAVFFGLSGTGKTTLSTDPKRALIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPDIYNAIRRDALLENVTVRSDGSIDFDDGSKTENTRVSYPIYHIENIVKPVSKGGHANKVIFLSADAFGVLPPVSKLTPEQTKYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLTLHPTKYAEVLVKRMEAAGAEAYLVNTGWNGTGKRISIQDTRGIIDAILDGSIEDAPTKHIPIFNLEVPTSLPGVDPSILDPRDTYVDPLQWESKAKDLAERFINNFDKYTDNAEGKALVAAGPQLD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSW_RIEPU
Sequence: MKKSHLYNRSLLSVTIILLIFSIIMVGSSSVSVGNRIRTDYLSFLKKNFIHSIISILCMIFVFNVPIYKWKKNKNKLILCSIILLLTLNYFGISNHGAKRWINIKIAFIQPSELVKISFSCYLSSYLSEKNKKTSTIQLISIILIVSKLLLSQPDFGTLVILYSSLLFMLFLIGKNFLFLSASSAIFTTIVLSLIYFRSYRAKRLISFLNPWSNYLGDGYQLVHSMLSFGRGKMFGQGIGNSIQKINFLPEPHTDFIISIIGEELGYLGIAMIVISLFFIFFQGMNIGRNALKDFQYFSGFLAYSISLLIIIQSIINIGSSIGILPIKGTTLPIISYGGSSKLITCIKIAILLRIDFETKMNKIQAFRR
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: GEFF_DICDI
Sequence: MTDKLKFKTSLLNKVPPPPPKSNQPSPSTSTPASPNVNSTNNSPSVSPATTSPIPSPGMSPLLTPENNNNNTNIPHQTSLLNNSISNKSSVSFLNNSGGNTINKSSPLSQSSSNIKNGGPIRTSTTLAQFSGSSLPNTENSSPPPSSSLISSSSSPTAESLLYSEDSIASGGTVTVDPNTKNGNIYNGNGLRNNSADILPHNNHTYCVGDDGFYLFGGTLPDGSYTNDFYTFQFAIKAWTILTFGSAPSIRTRHTGVLYNNSMYIFGGYSPSGPKNDIYVFSFDTQTWSEVQTEGTKPSPRYGHTAVVESGHMIVFGGISCDQTTKQQTVNNDIFSLNLDTKQWSQVLSTCPPSPRTHHTATMHKGNMYVFGGQDQQSNQVEDIVHCYTWASNSWKSIQFEGSSMTPRSDHSAVLFQDSIFISGGSSKSQTSQNLEIYEYDLYQKKCFKISSSTIVQNRISHSSVVKGNSILFWGGCTDNSFDYFSFGKDEFEEDYQDDYESNRVQNIPKELWEASLMKKHPEILELREKTLAFTGSKSFAKTLATPSFSENRLALSHQFVLQLIMEYLERNTYHKVIAAIQKESGVLHQPTESGESRLVSLLRLVKPRLRNKNVFDTDLSLFSKEEGNDPEVAVVDHLYHDYRHFDEEEDINVWEEGEDNNRNIRKVETDNNKVQIKAATFNKLIHYLAPKEKAFDPNFLKVFLYTHSSFTTSEKLLKKLIQRYQVPNSNANEPKYKSEVVEPVRQRVVDVLKYWVDKCPWDFNAGPTSSVLVATLNNFIDGSLTRDGNSNIKKLRELKKKLQHEDVRPYSEPPPEPKVPKNIFSPQLTLAHIDELEIARQMTLVESKLFGAIPPPEFMVRVIGYGEFQYNMATSPNLMTFVNRATDVSRWIVHTVLNESRDKKNKMKMLDKFIKTTECLRQLNNFQTLHSVLQGLQHPLLLSRPDLFTPRHREIIADHEMLFSKIDNYKLYREALARSQPACVPWIDIIREDFAQIERDQPSNMNNLINFTKRQNLYEILSKIGHYQFPYNLQIVHQVATFVNKLPKYSEYDLNLLSESLQSQVNSPLAGVYQPSLIGTTGSSSSINLGSARELNNSNRDSNNITGSSSNNNSNSSNSLSPIVKL
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP.
What are the official names of this protein?
Ras guanine nucleotide exchange factor F, RasGEF domain-containing protein F.
Protein: CFA45_BOVIN
Sequence: MPLSTAGVLSSASTASNRSRNRPRYRTKALSSEVDESLFGAIKPLTRSDSPIVLLRDKHAIRKTLTALGLDHKPETIQLITRDMVRELIIPTKDPSGQSLIMSPEEFERIKWASHVLTKEELEAREQAFKKEKEAIVDTVTTRKKIMKQKEMVWRNNRKLSDLEEVAKERAQNLLQRANQLRMEQEEELKDMKKIILNAKCHAIRDAQILEKQLIQKELDAEEKRLDQMMEVERQKSVQRQEELDRKRREERIRGRRHIVEQMEKNQEERSLLAEQREQEKEQMLEYMEKLQEEDLRDLEQRHQQKLKMQAEIKRINDENQRQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKMETEAKLRKSRLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKQVQARIATFDEGRRLKEEAQKRRERIEDIKRKKLEELRATGLPEKYCIEAERKANIPVNTSVN
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:34715025).  It is an AMP-binding protein that may facilitate dynein ATPase-dependent ciliary and flagellar beating via adenine nucleotide homeostasis.  May function as a donor of AMP to AK8 and hence promote ADP production (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 45.
What is the protein family that this protein belongs to?
Belongs to the CFAP45 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Located in the proximal region of respiratory cilia.
Protein: GLGB_CITK8
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHQTTAGLEVRALLPDATEVWVIEPKTGRKVGKLECIDSRGFFSGVLPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNAQRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAQHGQLYKFEMIDAHGKLRIKADPYAFEAQMRPETASLICGLPEKVVQTEERKQANRFDAPVSIYEVHLGSWRRHTDNNFWLSYRELADQLIPYVKWMGFTHLELLPVNEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFINAAHQAGLNVILDWVPGHFPSDDFGLADFDGTKLYEHSDPREGYHQDWNTLIYNYGRREVSNYLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVSMAEESTDFAGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVHRQYHHDKLTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKALHELDFDAYGFEWLVVDDNERSVLIFVRRDKVGNEIIVASNFTPVPRHDYRFGINQPGKWREIVNTDSMHYHGSNTGNGGVVHSDEIASHGRQHSLSLTLPPLATIWLVREGE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: SYS_AROAE
Sequence: MLDIQLLRTQIDAVAAALAARGANFDAAAFQSMENERKTLQTRTQDLQARRNTLSKQIGVLKSRGEDASAAMAEVGGIGDELKANEQALATLLERINAFVAGLPNLPHDSVPPGRDESANVEIARWGTPREFDFEVSDHVDIGSGLGGLDFETAAKISGSRFALMRDGLARLHRALAQFMLDVHTREHGYTEVHVPYLVNPDSMFGTGQLPKFEAELFSVMKDDGRFYLIPTAEVPITNIVRNELLAHDVLPLKFVGHTPCFRSEAGSYGRDTRGMIRQHQFDKVELVRIEHPDASWAALEELTGHAEAILRKLELPYRKVVLCTGDMGFSAAKTYDLEVWLPAQKTYREISSCSCTGAFQARRMQARFRNTQGKNELVHTLNGSGLAVGRTLVAVLENYQQADGSVVVPKVLVPWMGGIEVLEPRG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_BORBZ
Sequence: MNQSRRILRTVYLSLFLIGLFMLINDIFSSNILSSKSSDKEVQFDLNKSFDDNEISSVKSNSFNLINKSQDIVVETGIYVATFSTFKGNLVSLKLKNHLNLEKNPTDLINIDRKNETFFDISFDYFVDDLFLYKKIDDFNHEFKAYFKNNGKTYEYVKKYTFSKKDEYLMKFKVTVNGLEDYNLFDFDSYKIIFSSEIERLSDKAKLQYNNYLSQIIYYDNKLKYGKDGLRINNPRWIGSSTKYFGVLVSKENMEVEFKKERGTLKSFIINNVRNKKNISDEFFIYAGPKDNRYLDVFDKRDDNTFGLFDIFFGMSVEKSFWYLIQVPMQMVMQVFYDVIPNWGLSIIFLTIVVRILIFPLTFKGFRATAELSKLQPKMKELQAKFKHDPKKLNEEMGRLYKEEGVNPLGGCLPVILQLPIFFALYSLVNNLFLLRGASFIPGWIDDLSIGDSVYHFGYKLYFVSWTDIRILPFIMMFTQLGSTIVSSNMDLKNLGAQQKFLYFGMPIMFFFILYNMPSGLLIYWITTNIFTILQQYYIKMHLS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZAPA_SERP5
Sequence: MSAQPVDIQIFGRSLRVNCPPEQQDALNMAAVDLNERLQDLKVRTRVTNTEQLVFIAALNVCHELAQERLKTRDYASNMEQRIRMLQQTIEQALLEQGRISERQDAQFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.