PharMolix/UniProtQA huggingface dataset:
Protein: VPS41_YEAST
Sequence: MTTDNHQNDSVLDQQSGERTIDESNSISDENNVDNKREDVNVTSPTKSVSCISQAENGVASRTDESTITGSATDAETGDDDDDDDDDDDEDEDDEDEPPLLKYTRISQLPKNFFQRDSISSCLFGDTFFAFGTHSGILHLTTCAFEPIKTIKCHRSSILCINTDGKYFATGSIDGTVIIGSMDDPQNITQYDFKRPINSVALHSNFQASRMFVSGGMAGDVVLSQRNWLGNRIDIVLNKKKKKKTRKDDLSSDMKGPIMGIYTMGDLILWMDDDGITFCDVPTRSQLLNIPFPSRIFNVQDVRPDLFRPHVHFLESDRVVIGWGSNIWLFKVSFTKDSNSIKSGDSNSQSNNMSHFNPTTNIGSLLSSAASSFRGTPDKKVELECHFTVSMLITGLASFKDDQLLCLGFDIDIEEEATIDEDMKEGKNFSKRPENLLAKGNAPELKIVDLFNGDEIYNDEVIMKNYEKLSINDYHLGKHIDKTTPEYYLISSNDAIRVQELSLKDHFDWFMERKQYYKAWKIGKYVIGSEERFSIGLKFLNSLVTKKDWGTLVDHLNIIFEETLNSLDSNSYDVTQNVLKEWADIIEILITSGNIVEIAPLIPKKPALRKSVYDDVLHYFLANDMINKFHEYITKWDLKLFSVEDFEEELETRIEAASEPTASSKEEGSNITYRTELVHLYLKENKYTKAIPHLLKAKDLRALTIIKIQNLLPQYLDQIVDIILLPYKGEISHISKLSIFEIQTIFNKPIDLLFENRHTISVARIYEIFEHDCPKSFKKILFCYLIKFLDTDDSFMISPYENQLIELYSEYDRQSLLPFLQKHNNYNVESAIEVCSSKLGLYNELIYLWGKIGETKKALSLIIDELKNPQLAIDFVKNWGDSELWEFMINYSLDKPNFTKAILTCSDETSEIYLKVIRGMSDDLQIDNLQDIIKHIVQENSLSLEVRDNILVIINDETKKFANEFLKIRSQGKLFQVDESDIEINDDLNGVL
What is the function of this protein?
Required for vacuolar assembly and vacuolar traffic.  Acts as component of the HOPS complex that acts during the docking stage of vacuole fusion.  HOPS is an effector for the vacuolar Rab GTPase YPT7 and is required for vacuolar SNARE complex assembly.  It remains bound to SNARE complexes after vacuole fusion.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 41, Vacuolar morphogenesis protein 2.
What is the protein family that this protein belongs to?
Belongs to the VPS41 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: RF1_NITOC
Sequence: MKDSIRSKLETLAERQQELTALLAEPEIASAQKKFRELSQEYAQLEPVIGCFRDFEQAQSVLNESKALLQDQDPELRVLAQEEIAAAEKKLERLDRELHTLLLPSDPNDKRNIFLEIRAGTGGDEAALFASDLLRMYLRYAEQRGWRTEIMGDSPGEHGGHKEIIVRIVGAGAYSRLKFESGGHRVQRVPQTESQGRIHTSACTVAIMPEAEEIDDIDINPADLRVDTFRASGAGGQHVNKTDSAIRITHLASGIVVECQDERSQHKNRARAMSLLRTKLKSEEEAKLVAEETATRRSLIGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDEILQGNLDAIIDPLVAEHQADQLAALSD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_MACGG
Sequence: VLSPADKANVKAAWDKVGGQAGDYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKAHGKKVGDALSNAAGHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLASHHAAEFTPAVHASLDKFLASVGTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1/2, Alpha-1/2-globin, Hemoglobin alpha-1/2 chain, Hemoglobin alpha-I/II chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GLPB_ECO24
Sequence: MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRATWLSSPEVPVWPLPVKKICVVGISGLMDFQAHLAAASLRELDLSVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: HYDE_THEMA
Sequence: MTGREILEKLERREFTREVLKEALSINDRGFNEALFKLADEIRRKYVGDEVHIRAIIEFSNVCRKNCLYCGLRRDNKNLKRYRMTPEEIVERARLAVQFGAKTIVLQSGEDPYYMPDVISDIVKEIKKMGVAVTLSLGEWPREYYEKWKEAGADRYLLRHETANPVLHRKLRPDTSFENRLNCLLTLKELGYETGAGSMVGLPGQTIDDLVDDLLFLKEHDFDMVGIGPFIPHPDTPLANEKKGDFTLTLKMVALTRILLPDSNIPATTAMGTIVPGGREITLRCGANVIMPNWTPSPYRQLYQLYPGKICVFEKDTACIPCVMKMIELLGRKPGRDWGGRKRVFETV
What is the function of this protein?
Required for the maturation of the [FeFe]-hydrogenase HydA (By similarity).  Catalyzes the reductive cleavage of S-adenosyl-L-methionine (in vitro), suggesting it may contribute to the biosynthesis of an essential sulfur-containing ligand that binds to the hydrogenase active site [2Fe-2S] cluster (PubMed:16137685).
What are the official names of this protein?
[FeFe] hydrogenase maturase subunit HydE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. HydE family.
Protein: RS8_LEGPH
Sequence: MSMHDPIADMLTRIRNGQQAKHQQVTLVSSKLKEEIARVLKEEGYIQDFFIETLPNGLKSITLKLKYYHGRPVIEFIKRISRPGLRVYKSYKDLHSIPGFGVAILSTSKGIMTHVSAKVKGVGGEVICEVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL27_BRUSU
Sequence: MAHKKAGGSSRNGRDSESKRLGVKKFGGEAVLAGNIIVRQRGTKWHPGANVGLGKDHTIFATVNGSVSFRTKANGRTYVSVNPIAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: YOTE_BACSU
Sequence: MKEIEFEEVKKFVEVMSRRLRSTKVIKIHISYAEWLVAEVERLRGLVK
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YotE.
Protein: RS5_ENCCU
Sequence: MAEINLFEKYSYEEVKVNNVSLRPYINLSRRGIVPHAATTITKGTTGKARIPIAERFVCSLMRHGRNSGKKRLAINIFEDACFIIHSMTKKNPLQVLVDAIVNSGPREDTARIGRAGSMRRTSVDVSPLKRISIAISNLSAGIRNASFRNRITLAEAIANELIAASTNSQNSYAVNKKKEIERIAQSNR
What are the official names of this protein?
40S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHE1_STAA2
Sequence: MAVQLVLNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLIELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRTKIYIHAIDFSTKEQEVESIKTSLEKIVREVGEI
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit E1, Mnh complex subunit E1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS2_CALBD
Sequence: MPVLTMKQLLEAGVHFGHQTRRWNPKMAEYIFTERNGIYIIDLQKTVKKMDEAYEFVKSQVAEGKIVLFVGTKKQAQETIKEEAERCGMFYINQRWLGGLLTNFRTIKTRIERLKELQRMEEDGTFEVLPKKEVNLLRKEKERLLKYLGGIQNMPRIPDILYIVDPRKERNAVLEARKLGIPIVAIVDTNCDPDEIDYVIPGNDDAIRAVKLITSKIADAVIEGREGEQFTPATTSSQEVDKASEQVEIAADDIDEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ISK2_RAT
Sequence: MLRLVLLLLATDFAASDDSLDSSDSQLIKRSQFRTPDCHRFDYPVCSKHLSPVCGTDMNTYGNECTLCMKIREDGSHINIIKDEPC
What is the function of this protein?
As a strong inhibitor of acrosin, it is required for normal spermiogenesis.  It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects.  May be involved in the regulation of serine protease-dependent germ cell apoptosis.  It also inhibits trypsin.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 2.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein: ATP6_STREM
Sequence: MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTLKPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETTSGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEEFTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQAFVFTKLTATYLGKKVNESEE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTLD_CLOAB
Sequence: MKALHFGAGNIGRGFIGYLLYKSNYETTFVDIFDKVVDDINKYKRYTVITLSTSKNKEKVENVRAVNLKDSVALEKEVLEADLITTSLGLNNLKSTGELLRGFLKKRSEINDKPLDIIACENALFASDVLKKAILDGADEELKKYLEKSVGFPNCTVDRIVPNVDIEKELPIDVAVEDFYEWDIEKNKVKINNKIIGAEYVEKLDPYLERKLFLLNGAHATIAYLGYLKGYKYIHEAIKDKEINKIIVGFHSEAVQALSEKHKIDIQILKEYSNKLLKRFENEYLKDDVSRVGRDPMRKLSSNDRLITPLKLCCDLKIDFTNILFGVASGYLFNYKEDEKAQGIQNIITKEGIKKAISNVSQIKEGDYLNNMIAYKYEELKKQN
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RS19_BACVZ
Sequence: MARSLKKGPFVDGHLMTKIEKLNETDKKQVVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVFISEDMVGHKLGEFAPTRTYKGHASDDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y721_SHEB8
Sequence: MLIEIPNVFSKQEVSHLREQLDARRWIDGNQTSGAMATTRKRNQQLDKDDPVAVALGQQIMDRLLAHPQFVSAALPLQFYPPLFNRYQGGETFGYHIDNAIRSTPDGMIRTDLSATLFLSEPESYQGGELVIQDTYGQQSIKLSAGSLVLYPSSSLHQVTPVLSGERTAAFMWLQSMVRDEGQRRLLFQLDQSIQTLTAQQAAEQELFNLTGIYHNLLRRWSEL
What are the official names of this protein?
PKHD-type hydroxylase Shew185_0721.
Protein: VAC7_YEAST
Sequence: MTEEDRKLTVETETVEAPVANNLLLSNNSNVVAPNPSIPSASTSTSPLHREIVDDSVATANTTSNVVQHNLPTIDNNLMDSDATSHNQDHWHSDINRAGTSMSTSDIPTDLHLEHIGSVSSTNNNSNNALINHNPLSSHLSNPSSSLRNKKSSLLVASNPAFASDVELSKKKPAVISNNMPTSNIALYQTARSANIHGPSSTSASKAFRKASAFSNNTAPSTSNNIGSNTPPAPLLPLPSLSQQNKPKIIERPTMHVTNSREILLGENLLDDTKAKNAPANSTTHDNGPVANDGLRIPNHSNADDNENNNKMKKNKNINSGKNERNDDTSKICTTSTKTAPSTAPLGSTDNTQALTASVSSSNADNHNNNKKKTSSNNNGNNSNSASNKTNADIKNSNADLSASTSNNNAINDDSHESNSEKPTKADFFAARLATAVGENEISDSEETFVYESAANSTKNLIFPDSSSQQQQQQQQPPKQQQQQQNHGITSKISAPLLNNNKKLLSRLKNSRHISTGAILNNTIATISTNPNLNSNVMQNNNNLMSGHNHLDELSSIKQEPPHQLQQQQPPMDVQSVDSYTSDNPDSNVIAKSPDKRSSLVSLSKVSPHLLSSTSSNGNTISCPNVATNSQELEPNNDISTKKSLSNSTLRHSSANRNSNYGDNKRPLRTTVSKIFDSNPNGAPLRRYSGVPDHVNLEDYIEQPHNYPTMQNSVKKDEFYNSRNNKFPHGLNFYGDNNVIEEENNGDSSNVNRPQHTNLQHEFIPEDNESDENDIHSMFYYNHKNDLETKPLISDYGEDEDVDDYDRPNATFNSYYGSASNTHELPLHGRMPSRSNNDYYDFMVGNNTGNNNQLNEYTPLRMKRGQRHLSRTNNSIMNGSIHMNGNDDVTHSNINNNDIVGYSPHNFYSRKSPFVKVKNFLYLAFVISSLLMTGFILGFLLATNKELQDVDVVVMDNVISSSDELIFDITVSAFNPGFFSISVSQVDLDIFAKSSYLKCDSNGDCTVMEQERKILQITTNLSLVEESANNDISGGNIETVLLGTAKKLETPLKFQGGAFNRNYDVSVSSVKLLSPGSREAKHENDDDDDDDGDDGDDENNTNERQYKSKPNARDDKEDDTKKWKLLIKHDYELIVRGSMKYEVPFFNTQKSTAIQKDSMVHPGKK
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Positively regulates FAB1 kinase activity.  Major activator of FAB1 during hyperosmotic shock and can elevate levels of PtdIns(3,5)P2 in the absence of VAC14 and FIG4.  Directly involved in vacuolar membrane scission.  Required for normal vacuole acidification, inheritance and morphology.
What are the official names of this protein?
Vacuolar segregation protein 7.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein.
Protein: LEUD_CORGB
Sequence: MEKFTTHTGVGVPLQRSNVDTDQIIPAVYLKRVTRTGFEDGLFSNWRQNDPNFVLNTETYKNGSVLIAGPDFGTGSSREHAVWALMDYGFRAVFSSRFADIFRGNSGKAGLLTGIMEQSDIELLWKLMEQTPGLELTVNLEKQIVTAGDVVISFEVDPYIRWRLMEGLDDAGLTLRKLDEIEDYEAKRPAFKPRTNA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SYH_METVS
Sequence: MFQKPKGTRDFLPVEMKKRKLIEKKLRNIFDSYNFSEINTPTFESFELLSKKTGEEIRNQLFVFNDHGNREMGLRPEFTSSVARFYINEFKNTPKPVKMYYFGNCFRYENPQAGRYREFWQMGAELIGSNKSISDAEVLNMAIEGLKSINMDFEINIGHLGVLKGVFEKYSLSEEDETLIRRLIDKEDTEGLKQVLLKIEEEKNIEISKKVFEVLTLKGGKEVISKLKEKLTDFEKSLDALNNLDEILELVPHDYVVNFGIARGLDYYTGMVFEIYGKKEGARQVCGGGRYDNLIELFEGEKSPAVGFAYGFDRIILNIDDFEVQDDSIFIIPVKNDIFLLKECLKIAKTLRDFGNPVEIDLMGRKLNKALNYANSKNIKRVIIIGENDIFSGKIPLKNMETGEQVLIDVKDLKNFPC
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DE10B_HUMAN
Sequence: MAAAELADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITIIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYPAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESQVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI
What is the function of this protein?
May be a guanine nucleotide exchange factor (GEF).
What are the official names of this protein?
Putative DENN domain-containing protein 10 B, DENND10 pseudogene 1, Putative protein FAM45B.
What is the protein family that this protein belongs to?
Belongs to the DENND10 family.
What are the subcellular locations of this protein?
Late endosome.
Protein: PDXH_RUBXD
Sequence: MPEGARRDLAGLRREYTRAGLAEDGADPDPIRQFGRWFEEALRAGLYEPNAMVLATATPDGRPSARTVLLKGFDERGFVFYTNYGGRKSREIEANPRVALLFYWGELERQVRVEGTAGRTSEEESDAYFATRPRGSQLGAWASRQSEPAESREELERRLAELERRFEGRPVPRPPFWGGYRVRPERIEFWQGRENRLHDRLLYAREGPGWRRVRLQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: YOHJ_ESCF3
Sequence: MSKILNTIWQYVRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAQWVNPGCYLLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAISTLVVFLVVSWSSQLVHGERKVVGQKGSKE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXO_ASPFU
Sequence: MDGGTFDIQPIGRFYGSNTTIRRPREITCFSYDAEHKFHLGDSSLRYYYTPRLPADLNRGFDTFQKLDDTADEHLDALLETIMALEKETGKRCEADIITWRGMMTKILTAPFDNLNGFEMNATCFQVGGENNLYKIQQKQIQENQRMPPGMASQDLMAYWGYKFETLCLLQQPWDPTPRAEIESREDLVVNNNAQYCSVVRTGIGSTRLIIGGEVDAVWDCKPDRKEDPINWVELKTSAEIRNDRDMIKYERKLLKFWAQSFLLGVPKIIVGFRDNHGIVHRLEELETASIPNKVKKLGRGTWDGNICINFAAAFLEWLKSTIKEGGTWRIRKLEKSSLIQVFKIEETGTGDIISRSFLDWRSRS
What is the function of this protein?
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity).  The NAD-cap is present at the 5'-end of some RNAs and snoRNAs.  In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity).  Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).
What are the official names of this protein?
Decapping nuclease RAI1, NAD-capped RNA hydrolase rai1, DeNADding enzyme rai1.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FAEB_TALFU
Sequence: MAIPLVLVLAWLLPVVLAASLTQVNNFGDNPGSLQMYIYVPNKLASKPAIIVAMHPCGGSATEYYGMYDYHSPADQYGYILIYPSATRDYNCFDAYSSASLTHNGGSDSLSIVNMVKYVISTYGADSSKVYMTGSSSGAIMTNVLAGAYPDVFAAGSAFSGMPYACLYGAGAADPIMSNQTCSQGQIQHTGQQWAAYVHNGYPGYTGQYPRLQMWHGTADNVISYADLGQEISQWTTIMGLSFTGNQTNTPLSGYTKMVYGDGSKFQAYSAAGVGHFVPTDVSVVLDWFGITSGTTTTTTPTTTPTTSTSPSSTGGCTAAHWAQCGGIGYSGCTACASPYTCQKANDYYSQCL
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.  Binds strongly to cellulose.
What are the official names of this protein?
Feruloyl esterase B, Cinnamoyl esterase, Ferulic acid esterase B, FAEB.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 1 (CE1) family. Feruloyl esterase type B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: REX_CLONN
Sequence: MEKKRNISMAVIRRLPKYYRYLAELMDNDVDRISSKELSEKIGFTASQIRQDLNNFGDFGQQGYGYNVKDLYNEIRSILGLDENYNIAIIGAGNIGQAIANYTNFDKMGFNLKGIFDVNPKLLGLKIRDVEIRDIDQLESFLQEEKIHIGVICVTKSNAQDVCNTLIKNGVKGIWNFAPIDLNGADNVVIENVHLSESLLTLTYLLNGFN
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_ROSDO
Sequence: MRVGLYPGTFDPITLGHLDIIRRASALLDKLVIGVAINRDKGPLFCLEERVAMVEAESIKIAAMTGLEIVTHPFENLLIDCARDVGATVIVRGLRAVADFEYEYQMVGMNRQLDDTIETVFLMAEAEHQAIASKLVKEIARLGGDIEKFVTPEVNAALLNKIGRAG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_BURVG
Sequence: MTTTELVALLHLASPALPIGAFSYSQGFEAALDANLIRDADTARDWIASGLTDVLAHGELPFLAHQLARWHAHDADALARENAWFVASRESAELRRETEQMGWSLAQLCASLEWGDAARRATLAALKPIALPTAFAYAAAAHDAGADATLAAYAFGWVENQTSAALKAVPLGQLAGQRIIVALRGAIDAAVKRALATPPDAVNTFAPQLGILSARHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_EQUHE
Sequence: VQLSGEEKAAVLALWDKVNEEEVGGEALGRLLVVYPWTQRFFDSFGDLSNPAAVMGNPKVKAHGKKVLHSFGEGVHHLDNLKGTFAQLSELHCDKLHVDPENFRLLGNVLVVVLARHFGKDFTPELQASYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL25_CAUSK
Sequence: MAEIILNVEIRDRAGTGGSRETRRQGKVPGVLYGGPLAPVNIAVKGNEFRKALHTGKLLGHLVTLQHGDEKQSVIAKAVQFHPVTDEPLHFDLYRVDEHQLIKIEIPVHFKNHDISVGLKKGGTLEIIRHTVELACPADKIPEELVIDLASHDIGDTIRISEIKLPEGVRPAMERDFVIANLKASAASQSTEGDTTAEA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PYRH_AZOC5
Sequence: MPGLPYPRILVKVSGEALMGSEPFGLHPPTVARIARELVAARELGCEVAVVVGGGNILRGARVAGEDLDRSTADHMGMLATVMNCLALEAAVEAAGQPARTMSAIPMPTVCEPYARQPAQRHLRRGRVVLLAGGTGNPYFTTDTGAVLRAAELDCDAVLKATNVDGVYTADPKTDPTATRYERITHDQALAYDLKVMDAAAFALAREASLPIIVFSIRDPGAIVAAAQGEGRVTVVSP
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_ANASK
Sequence: MMDAVRARIRDVPDFPKKGIVFKDITPVLSDPHTFREVIDAFVERWKGERVDKVIGIESRGFIFAAPIAYALGAGFTIVRKPGKLPWETIREVYALEYGEGALELHIDAIGPGDRVLVVDDVLATGGTAGAAGRLVVRQGAELLGYAFLAELSFLNGARQLGHAKVHSLLTF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYPH_YEAST
Sequence: MSQVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLGSPSGATKARIVVAKSGEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Involved in histone deacetylase complexes, suggesting a function in chromatin.  Imports fructose-1,6-bisphosphatase (FBPase) into the intermediate vacuole import and degradation (Vid) vesicles.  Regulates the meiotic gene program via the Set3C histone deacetylase complex to promote efficient sporulation, and the prolyl-isomerase activity is required for this function.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin, CPH, Cyclosporin A-binding protein, PPI-II, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: CINA_STRSY
Sequence: MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQTLATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAMFSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADVIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEDILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVVGQLGIESGWLSEEADCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLRGYSWQYLRQLACLQAWDFVRNTL
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: DDL_MYCBO
Sequence: MSANDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETALARGVGLH
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.