PharMolix/UniProtQA huggingface dataset:
Protein: HAPX_ARTBC
Sequence: MSTSAGTPTSAHAPLSIAPASTPHQRSLSVKPLAAAPSPAPVTQCSITSKEWIVPPRPKPGRKPATDTPPTKRKAQNRAAQRAFRERRAARVGELEEQIKKIEEENEREEAALKKTIQQQQQQIEEYKSQLLWWKNRCKAVEDELMTEKVAKEDAIKQLERINNSGRTTNNGNSVIGGCERCSSTRCQCIDDAFNIANITQMQTDDPHSKRGRSPSQGATQKRHRSNPEIKTEPEDLETDFTHSFSLRRHSRTGNDATTPILLDPCGFCQDGSPCICAEMAEDQPSDRSNQPSQLTKLPPIQNISQFTPPPSEGDVLSKSATLVSSNKSNPCANGPGTCAQCLADPRSSVFCKSLAASRASTRQEGGCCGGGGGKDGCCKNRSSGSDSSKQATSPITLSCADTFTTLSLHPKFASASNELSNWIPQLHTLPNPQNLNPDRRRDQNLTNRPALEVEAASVMGVLRYFDRRFADSK
What is the function of this protein?
Iron regulator crucial for the adaptation to iron starvation and iron excess, but is dispensable for virulence (PubMed:26960149).  SreA represses the expression of hapX and the siderophore system during iron sufficient conditions by an iron-sensing mechanism, while hapX represses sreA and activates the siderophore system during iron-limiting conditions, resulting in efficient iron uptake and inhibition of iron-consuming pathways (PubMed:26960149).  HapX targets include genes encoding a number of key iron-regulated factors such as the vacuolar iron importer cccA, as well as hemA, cycA and lysF involved in heme biosynthesis, respiration and lysine biosynthesis, respectively (PubMed:26960149).  Activation of the vacuolar iron importer cccA during high iron conditions is essential for iron detoxification (PubMed:26960149).
What are the official names of this protein?
bZIP transcription factor hapX, Iron acquisition regulator hapX.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. YAP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CDSA_THEMA
Sequence: MDDLKTRVITASVVAPFVVLCFVSYESLIGLVSAILILAGYELITLEMKERDARFFYVILLALYPVLYGLVFEEPTQPLSILFITGVVFSLITDKDPSQVFKTVAAFSIALIYVTFFLSFFLPIYRDFGAANALLVLTSTWVFDSFAYFTGLKFGRTRISPRYSPRKSLEGVIGGFLGVVIYTFLYRLVVNDLLSVNVISFRTFLPFAATVAIMDTFGDIFESALKRHYGVKDSGKTLPGHGGMLDRIDGLLFVAPVSYIVFKILEGVVR
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL36_KARMG
Sequence: MKKVTSLKKRSDNCKIVKRKGCLRIINKLNPKFKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ATPG_PSYA2
Sequence: MASLKEIRAKVTSIKSTQKITRAMQMVAASKMRRAQERMEVGRPYADSMRRVISHLVHASSDYKHPYMVNRPVNKVGYIVITSDRGLAGGLNINLFKALTKSIQQYQDQSVQAEFAVIGAKGVSFFKNFGGKVTSAVTDYGDKPTFEQLNSPVQAMLEDYSNGKIDRIYVVYNKFVNAMTQKPTINQLVPLPDSAFAEEESGIQTELSWDYIYEPDIKTLIDELLGRYIESIVYQAVMENIASEQSSRMVAMKAATDNAGDLINDLQLVYNKLRQAAITREISEIVGGAAAVS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IF2_PROMT
Sequence: MTSSGKIRIYELSKDLSLDNKDVLDAARKLAIAAKSHSSSISSLEANQIKDFLKKSNTINTTIKSSKNLDKQILSVKKNPVKTQKDQKTEPKKKNHDQTELSQAKLNTLLKPSQTLIKSQGSSQANNQKALKNKFPAKQQITSPSKPNKPLPPNPRVEVKPIISKPLTQAERAIPQSEQKKDGQFINQPKRSELAKKSIGQPKQINPQEPKRPLAPPSRPKIDIQDKKPLQPNNQKAKTRINQGEISPQKVGQGNIQKIKSQNKQNAPSRTPQPPTKGNTLELVGAPIRKEKPVNKPHTNEVRNKPVMPSRPGAPKPPTAANRQGLSNRPGSNNRIGGTGRPGSPNRQGPNRGGVANRTTQGQNRPGANNRAGAPVRSGSPNRGGMQNRPGVPTRSLGGPNRSNNRPGVPSGMRKPVAPSELMQLQKPQARPNAPQRKTDSPTSLRPKRENSTGARPPVNRPTPAAPKKPAHRPGGTAAAPRRTGRPDWDDSAKLDALRNKSPQKQRQKVHIIGENDDALTAERGGFAGEQQAVVLSASLARPSKPKVGKRNNGKPLTALKKRKKETTRQRQRRRAMELRASREAKLVRPEMIVVPEDNLTVQELADMLSVESSEIIKSLFFKGITATVTQSLDLATIETVAEEFGVPVLQDDVEEAAKKTVEMIEEGDLKYLIRRPPVVTVMGHVDHGKTSLLDAIRKARVAAGEAGGITQHIGAYQIETEHDGSTKKLTFLDTPGHEAFTAMRARGTRVTDVAILVVAADDGVRPQTLEAISHARAAKVPIVVAINKIDKEGSSPDRVKQELSEQDLLSEEWGGDVVMVPVSAIKGENIDKLLEMVLLVTEVEDLQANPDRLAKGTVIEAHLDKAKGPVATLLVQNGTLKSGDVVAAGPVLGKVRAMVDENGSRIKEAGPSCPVEALGFSEVPTAGDEFEVYPDEKAARAVVGERATDARAARLAQQMASRRVSLSSMSGQASEGELKELNIILKADVQGSLEAILGSLEQLPKDEVQVRVLLSAPGEITETDIDLAAASGAVIVGFNTSMASGAKRAADANGVDVREYEVIYKLLEDIQLAMEGLLEPEMIEEALGVAEVRAIFSIGKSAVAGCYVTNGKIQRNCRARVKRGKQIVFEGDLDSLKRNKDDVKDVSTGFECGIGCDRFANWEEGDQIEAFKLVTQRRKLNN
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_LISW6
Sequence: MKFAVIQFPGSNCDLDMLHAIRDSLGEEAEYVWHAETSLEGFDAVLLPGGFSYGDYLRTGAIAKFSSIMPEVLRFAETGKPVLGVCNGFQILTEIGLLPGALIRNNNLHFICKTVPLRVVNGNTIFTGLYEDNEVIHVPVAHGEGNYYCDDETLLKLKENNQIVFTYDSVNPNGSRADIAGIVNERGNVLGMMPHPERAVEDIIGGTDGLRLFQSIVQAWKEEQVNA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_SYNE7
Sequence: MPYYAALGLDVGRRRIGVAGCDRLGITVQGLTTIVRRDFASDVAAISAIAKERQVELLVIGLPYSMDGSLGSQAKQTQRFATRLSKALQLPITYVDERLTSFEAEEMIKAEGRSPSRDKGAIDRKAAALILQQWLDEQREPRRFGSTQH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_CUPTR
Sequence: MARIAGVNIPNHKHTEIGLTAIYGIGRSRARKICEATGVPFDKKVKDLTDADLEKLRDEVGKVTVEGDLRRETTMNIKRLMDLGCYRGMRHRKGLPMRGQRTRTNARTRKGPRKAGVALKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PLPL3_HUMAN
Sequence: MYDAERGWSLSFAGCGFLGFYHVGATRCLSEHAPHLLRDARMLFGASAGALHCVGVLSGIPLEQTLQVLSDLVRKARSRNIGIFHPSFNLSKFLRQGLCKCLPANVHQLISGKIGISLTRVSDGENVLVSDFRSKDEVVDALVCSCFIPFYSGLIPPSFRGVRYVDGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKSTNFLHVDITKLSLRLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAFRFLEEKGICNRPQPGLKSSSEGMDPEVAMPSWANMSLDSSPESAALAVRLEGDELLDHLRLSILPWDESILDTLSPRLATALSEEMKDKGGYMSKICNLLPIRIMSYVMLPCTLPVESAIAIVQRLVTWLPDMPDDVLWLQWVTSQVFTRVLMCLLPASRSQMPVSSQQASPCTPEQDWPCWTPCSPKGCPAETKAEATPRSILRSSLNFFLGNKVPAGAEGLSTFPSFSLEKSL
What is the function of this protein?
Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids.  Does not esterify other lysophospholipids.  Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA (PubMed:22560221).  Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides (PubMed:15364929, PubMed:20034933, PubMed:22560221).  In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety (PubMed:21878620).  However, the triacylglycerol hydrolase activity is controversial and may be very low (PubMed:22560221).  Possesses phospholipase A2 activity (PubMed:15364929).
What are the official names of this protein?
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3, Acylglycerol transacylase, Adiponutrin, ADPN, Calcium-independent phospholipase A2-epsilon, iPLA2-epsilon, Lysophosphatidic acid acyltransferase, Patatin-like phospholipase domain-containing protein 3.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Lipid droplet.
Protein: Y3602_PHOLL
Sequence: MSIQNSLPDYQSFDETLHQQSVALTAAEMHGLISGLLCGGNRDSSWQVLVHDLANDGLAFSHPLAQKLRELREITFESLDDSNFAFGLLLPDEEDNVFERADALAGWVNHFLLGLGVAQPKFADRKEISEIIGDLRNIGLLGYEEGDDQEELSQALEEVLEYVQVAAQLCYIAFTEPKTVLIAKNDKPTLH
What are the official names of this protein?
UPF0149 protein plu3602.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: EDC3_CHICK
Sequence: MATDWLGSIVSINCGESLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDSRQCGDLQQADTGIPGVGCQVGPSQNGTGKMLKKPFSSSAPQNIPRRTDMKNQDIIISPQQQCSKSYMDRHMETLSQSKGFRRRHNSWSSSSRHPNQVTPKKSGLKNGQMKSKDDECFGDDIDEIPDTDFDFEGNLALFDKAAVFEEIETYERRSGTRSRGTPNEKPARYRHDENILESEPIVYRRIVVPQNANKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALSLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLSNHDVHVILFLPNFVKMLESITNELNLFSSTQGQQVSSVKDLPDTPVDLVINCLDCHENAFLRDQPWYKAVVDWANQNRAPVLSIDPPISEMEQGIDAKWSLALGLPLPLGERAGRVYLCDIGIPQKVFQEVGINYHSPFGCKFVIPLHST
What is the function of this protein?
Binds single-stranded RNA.  Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity).
What are the official names of this protein?
Enhancer of mRNA-decapping protein 3, YjeF domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDC3 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Processing bodies (PB).
Protein: TRMFO_CALBD
Sequence: MEIVVIGAGLAGVEAANVISKFGIKVKLFEMKPKKFSPAHKIDNFAELVCSNSLKSKLLTNASGLLKEEMKVFGSLVMEAAEATSVEAGQALAVDRYKFSEYITQRIKHNGLISIIHEEVTEVPRDKVVVVSTGPLTTESLLSDISKLCNSKNLYFFDAAAPIVLKDSIDFSKAFFASRYNKGSNDYINCPMTKEEYERFYWELVNAEVIEVKDFEKDLLFEGCMPIEEMARRGIDTMRYGPLKPVGIIDPRTGKMPYAVVQLRKDTQDGKLYNMVGFQTRLKWSEQKRVFRLIPGLENAEFVRYGVMHKNSYINSPEVLTKYLFLKKYPNIFFAGQITGVEGYLESASTGIIAGINAARQILGKEPISLPPNTCIGALIEYITTPKKDFQPMNANYGIISIDDEISKIKDKEKRKLLIAQKSLNICRELANKIFE
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS3A_CVPFS
Sequence: MDIVKSINTSVDAVLDELDCAYFAVTLKVEFKTGKLLVCIGFGDTLLAARDKAYAKLGLSTI
What are the official names of this protein?
Non-structural protein 3a, ns3a, Accessory protein 3a, X2a protein.
Protein: KRDE_DESAH
Sequence: MKIKEITIWKEDLALTRPYTIAYETISAVENVFVLLETDNGITGIGAGSPAEDVTGETITATETALSLKLAPILQGKDIRSCFSLLKELNTALADTPAALAAADIALHDLAAKTMGLPLVDLLGRVHDRLPTSITIGIMPVKETLAEAEEYLGRGFSILKIKTGLNVEEDIERIIRLNETFKSKICMRVDANQGYEVEELHHFFKKTVGLVEFIEQPLKAEHLEKMGQLPQAIRRVSAADETLLGPRDAAQMLHAPRPFGIFNIKLMKCGGIAPGLEIANMAGHADIDLMWGCMDESIVSIAGALHAAFSSRATRYLDLDGSLDLARDIVNGGFILENGWMRTTDQPGLGVKRI
What is the function of this protein?
Catalyzes the epimerization of L-Lys-L-Arg to L-Lys-D-Arg (in vitro).  Catalyzes the epimerization of positively charged dipeptides, with a preference for substrates with a basic amino acid in the second position.  Has epimerase activity with L-Lys-L-Lys, L-Arg-L-Arg, L-Val-L-Arg, L-Val-L-Lys and L-Ala-L-Arg (in vitro).
What are the official names of this protein?
L-Lys-D/L-Arg epimerase, Cationic dipeptide epimerase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: RNPH_ZYMMO
Sequence: MRPSGRTPDQLRSLSIETGFTRHAEGSCLISFGDTRVLVTASLEERLPSWLRGKGQGWVTAEYGMLPRSTHSRTNREAARGKQSGRTQEIQRLIGRSLRAGIDLKKLGERQITIDCDVLQADGGTRTASISGGWVALRLAVNKLLASGQLTEDPIISQVAAVSCGISQGVPVLDLDYAEDSTAEADANFVMMGDSRLIEVQASAEGAPYDEEGLLRLLRLARMGCQQIFAEQKKAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PA2B_BUNFA
Sequence: MNPAHLLVLLAVCVSLLGAANIPPQSLNLYQFKNMIQCAGTQLCVAYVKYGCYCGPGGTGTPLDQLDRCCQTHDHCYDNAKKFGNCIPYFKTYEYTCNKPDLTCTDAKGSCARNVCDCDRAAAICFAAAPYNLANFGINKETHCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits blood coagulation and shows bactericidal activities against both Gram-negative and -positive bacteria (E. coli, MIC=0. 4 uM and S. aureus, MIC=0. 1 uM).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 BFPA, svPLA2, Antimicrobial phospholipase A2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_LACLS
Sequence: MKLQKPKGTADLLPAETAKWQYIEEIARGVFNDYNFKEIRTPMFESYELFSRATGETSDIVTKEMYDFEDKGGRHIALRPEGTASAVRAYIENKLYAPEVVKPVKLWYDAPMFRYERPQSGRLRQFHQFGVECLGLKNSAVDVEIIAMADTLFRQLGISGVKLSLNTLGDMESRKAYRQALIDYLTPFENQLSEDSRRRLNENPLRVLDSKEAEDIAIVKNAPAILDYLNETSKAYFEEVKALLEALNIEYTIDSNMVRGLDYYNDTIFEFIVNFDGKELTVCGGGRYDGLVEYFDGPATPAFGFGLGIERLLMIAEKQEINFIPEETLDVYIAVMGEKANLEATKLAESLREQAFKVERDFSNRKLGAQFKTAEKLGAELIITLGEDEVRTGQIKVKHNQTRKQVETTLKAVHESFAPIFEEIYADEIN
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_PELUB
Sequence: MNKKPIILGIESSCDETAASIITENEQGMPTILSSIVSSQVDVHKEFGGVVPELAARSHMEKIDLITKKAFDKSGVKMEDLDAIAATAGPGLMVCLSVGLSFGKAMASSLNKPFIAVNHLEGHALSPKLNSELNYPYLLLLISGGHTQFLSVQGLGNYKRLGTTIDDAVGEAFDKTAKLLGIEFPGGPQIEVYAKKGDPNKYELPKPIFHKGGCNLSFAGLKTAVLKISKQIKTEQEKYDLAASFQKTIEEILYKKSKIAFEEFKKMNTINKNKFVVAGGVAANKRIREVLTNLCKEEEFEAIFPPINLCGDNAAMIAMVGLEKFKLKQFSELDSPAKPRWPLDADAAFLKGAGVRL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_LACE2
Sequence: MADKRDYYEVLGVPKDADDAAIKKAYRQLAKKYHPDMNPGDKEAEIKFKEASEAYAVLSDAEKRRQYDQFGHAAFEGGAGGAGAGGFDFDFGDMGDIFGDLFGGMFGGGGSRRNSNGPRRGADVRVNVRITFDESVRGTTKKIDVTLKDECSSCHGTGAKPGTSPETCSKCGGRGQVTFTQQSFLGMVRSQQPCPDCHGTGKIIKEKCPDCYGTGYISSKKTIEVNIPAGIDNGQCVRIQGKGEPGVNGGPRGDLLVAVIISASTEFERDGYNIFSNVVISYPTAVLGGEIKVKTVDGEVLYEVKPGTASGTRVRLKGKGMPSVRNAAQRGDHYITLIVDIPTKLNQEQKDALMAYEKALTGNERHGKKKGLFGK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPI_BACCZ
Sequence: MSFNLRGAVLANVSGNTQDQLQETIVDAIQSGEEKMLPGLGVLFEVIWKNADENEKHEMLETLEQGLKK
What are the official names of this protein?
Small, acid-soluble spore protein I, SASP I.
What is the protein family that this protein belongs to?
Belongs to the SspI family.
What are the subcellular locations of this protein?
Spore core.
Protein: RNTR_HYPRU
Sequence: ASKTCPSNTPLSCHNTTVVQDTCCFIPSGQLLQTQFWDTDPSTGPSDSWTIHGLWPDNCDGSFPQTCDASRAYTNITDILTAMGADDTLQYMQTYWKDYQGNDESFWEHEWGKHGTCITTLDPGCYDDYVPTEEAADFFSKTVSLFKTLPTYQWLADAGITPDGSKSYALDDIQSALSQQHGAEVTLGCDGKTLNEVWYHFNVKGSLQDGQFVAAEPDGAKSTCPDDVYYDPKK
What is the function of this protein?
This is a base non-specific and adenylic acid preferential ribonuclease.
What are the official names of this protein?
Ribonuclease Trv, RNase Trv.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: SCX30_TITSE
Sequence: MFKLAIILALLFFGARAGAVRDGYPILSDGCKYTCKPLGENQNCSRICKEKAGSWYGYCYMWACYCTDVSKKAVLFGDSGTPECHVWIK
What are the official names of this protein?
Putative sodium channel toxin Ts30, Putative NaTx, Tityustoxin-30.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_PHATC
Sequence: MVMNIRVLTPDRVICSTTADEVVLPGLTGQVGVLDGHAALITALETGLLRIKLNDKWTPIILCGGLAEIDRDRVTVLVNDVEELTDIGLSEATQELEKATLAVENAKTSKERLDASVELKKATARLEAVNYLS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RN220_MACFA
Sequence: MDLHRAAFKMENSSYLPNPLASPALMVLASTAEASRDASIPCQQPRPFGVPVSVDKDVHIPFTNGSYTFASMYHRQGGVPGTFANRDFPPSLLHLHPQFAPPNLDCTPISMLNHSGVGAFRPFASTEDRESYQSAFTPAKRLKNCHDTESPHLRFSDADGKEYDFGTQLPSSSPGSLKVDDTGKKIFAVSGLISDREASSSPEDRNDRCKKKAAALFDSQAPICPICQVLLRPSELQEHMEQELEQLAQLPSSKNSLLKDAMAPGTPKSLLLSASIKREGESPTASPHSSATDDLHHSDRYQTFLRVRANRQTRLNARIGKMKRRKQDEGQREGSCMAEDDAVDIEHENNNRFEEYGWCGQKRIRATTLLEGGFRGSGFIMCSGKENPDSDADLDVDGDDTLEYGKPQYTEADVIPCTGEEPGEAKEREALRGAVLNGGPPSTRITPEFSKWANDEMPSTSNGESSKQEAMQKTCKNSDIEKITEDSAVTTFEALKARVRELERQLSRGDRYKCLICMDSYSMPLTSIQCWHVHCEECWLRTLGAKKLCPQCNTITAPGDLRRIYL
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity).  Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 and promotes Wnt signaling (By similarity).  Plays a critical role in the regulation of nuclear lamina.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF220, RING finger protein 220, RING-type E3 ubiquitin transferase RNF220.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZUR_ALCSP
Sequence: AECSVDIAGNDQMQFDKKEITVSKSCKQFTVNLKHPGKLAKNVMGHNWVLTKQADMQGAVNDGMAAGLDNNYVKKDDARVIAHTKVIGGGETDSVTFDVSKLAAGEDYAYFCSFPGHFALMKGVLKLVD
What is the function of this protein?
Transfers electrons from cytochrome c551 to cytochrome oxidase.
What are the official names of this protein?
Azurin.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS8_ORITI
Sequence: MSMSDTLADMLTRIRNAQRSRLMYVNAPSSRRKEAILDVLVKEGFIHSFLVHEVRNGVKEINIKLKYSPKGESNIKEINRVSTPGKRVYLSIKKLRPYYNNMGIYIISTSKGIMSDREARKLGVGGEVICKVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GREA_PSESM
Sequence: MIKYPMTVQGARALEEELTHLTKVIRPKLSQDIGTARELGDLKENAEYHAAREQQGMVEARIRDIEGRMQNAVVIDVTTIAHTGKVIFGTTVEIANVETDESVVYQIVGEDEADIKKGKISVGSPIARALIAKEEGDVVVVKTPSGVIEYEIIEVRHI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: Y4613_KLEP3
Sequence: MDYEFLRDITGVVKVRMSMDHEAIGHWFNEEVKDNLALLDEVEQAARTVKGSERSWQRAGHEYTLWLDGEEVMIRANQLEFSGDEIEEGMSYYDEESLSLCGVEDFLQVVAAYREFMQQR
What are the official names of this protein?
UPF0231 protein KPK_4613.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: SNAB6_LYCMC
Sequence: MKIVIIFFIAMMAVGVYSKDGYLVKKNGCAYDCTVLFGDSNCNGECKAFKASWGSCYAFACYCRGLPDSVPTYPSSKTCSS
What is the function of this protein?
Binds voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin LmNaTx11.6.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.