PharMolix/UniProtQA huggingface dataset:
Protein: CODY_HALH5
Sequence: MSLLSRMRKINDMLQKSGVQHVNFREMAETLRDVISANIFVVSRRGKLLGFAIKQEIENERMKKMLEDRQFPEEYTTGLFKVEETSANLDINSEFTAFPVENKELFKTGLTTIVPISGGGQRLGTLILARLNDSFNDDDLILAEYGATVVGMEILHEKTQEIEEEARSKAVVQMAISSLSYSELEAVEHIFEELDGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLVELEKIKAS
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
Protein: ATPA_ANOFW
Sequence: MKCMSIKAEEISALIKKQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMSGELVEFANGVMGLALNLEENNVGIVILGPYTGIKEGDEVRRTGRIMEVPVGEALIGRVVNPLGQPVDGLGPIETTETRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAVDTIINQKGKNMICIYVAIGQKESTVRNVVETLRKYGALDYTIVVTASASQPAPLLFLAPYAGVTMGEYFMYKGQHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGAGSLTALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGAAQIKAMKKVSGTLRLDLAAYRELEAFAQFGSDLDKATQAKLARGARTVEVLKQGLHEPLPVEKQVAIIYALTRGFLDDIPVEDIRRFEKEFHAWLDKDENGQKLMEHIRTTGDLPNEEDFNKAIEAFKKTFVVSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRD_KOCRD
Sequence: MRLYPAFFKAAFSWMDPELAHTLGFAGIKLAHRTGLGRVLSRVTAPDEGAEVNVMGLTFPSPFGLAAGFDKGATGTHALTQLGFGHVEIGTVTGQAQPGNPRPRLFRLVRDRAVINRMGFNNDGAEAVAPRVAAALQTLAQESIRTGRRRPVVGVNIGKTKAVGLEDAAADYVRSTRVLAPYADYLVVNVSSPNTPGLRQLQELDALRPLLLAVRAEADRVTGRRVPLLVKIAPDLADEDVTAVADLALELGLDGIVATNTTIAREGLGLRTNHDDVAACGAGGLSGAPLRRRSLEVLRLLKEHAGEQLVLVSVGGVTTARDVMERLDAGASLVQGYTAFLYEGPFWAGRINRGLRRAAREGR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SECB_XANC5
Sequence: MSDEILNGAAAPADAAAGPAFTIEKIYVKDVSFESPNAPAVFNDANQPELQLNLNQKVQRLNDNAFEVVLAVTLTCTAGGKTAYVAEVQQAGVFGLVGLDPQAIDVLLGTQCPNILFPYVRTLVSDLIQAGGFPPFYLQPINFEALYAETLRQRQNEGTSLADSEPAGNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFTC_BURCE
Sequence: MHAGEAVQQLKKAFETVASFDFRDALSKASTPVTVVATNGPFGLAGLTCSAVCSVCDRPPTVLLCINRKSYAAGIIKSNGVLSVNWLAAGQAVISQTFAGVGSVPMEERFADKGWQTIATGAPYRMDAAVSFDCTIANIVDVGSHSVIFAEVVARNHAEECTPLIYHRRQYATTRSLAE
What is the function of this protein?
Reductase component of a two-component system that degrades 2,4,5-trichlorophenol.  TftC provides the FADH(2) required by TftD.  TftD oxidizes 2,4,5-trichlorophenol (2,4,5-TCP) to 2,5-dichloro-p-benzoquinone, which is chemically reduced to 2,5-dichloro-p-hydroquinone (2,5-DiCHQ).  Then, TftD oxidizes the latter to 5-chloro-2-hydroxy-p-benzoquinone.
What are the official names of this protein?
NADH:FAD oxidoreductase, Chlorophenol-4-monooxygenase component 1, Two component enzyme C.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family.
Protein: AROC_TROWT
Sequence: MLRWFTAGESHGMELVAILEGLPAGIPVSLEHIGNELSRRRLGFGRSARQKFEKDLVTLSAGVLHGSTLGSPVAIRITNSEWGKWEKIMTPEVPCKSDMSDAKRAQGLYKPRPGHADLVGMQKYGFQNSRLVLERASARETAARVACGAVAKAFLQQLDIFILSHVKQIGSIKIDYEQGAYPRFCDLEAIDSSPVRCFDKNTSEKMKDELHRIKRCGDTLGGVFEVLAYGLPPGLGSYVHWDRRLDAMLSAAIMSIQAVKAVEIGDGLAISALPGSEAHDQIVLESGLLTRMSNHSGGVEGGVTTGSALRISGSMKPISTVPRALKTVDISTRQPANADHQRSDICAVPAAAVVGESMVALTISCAILDKFGGDSLCEIKRNFSGYLNSIPKNLMSVIER
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SP2M_BACSU
Sequence: MRKISYKDMFLRHVKDHLSLYIFVSVLFFMGVIFGAIIVNSMTISQKEDLYYYLSQFFGQLSDGKQASSADMFGQSIFHNAKYLGLMWILGISVIGMPIIFIMIFLKGIVVGFTVGFLVNQMGVSGFFLSFVSVLPQNVLLIPAYLIMGTCAIAFSLKLIRQLFVKRSLHDAPIQWFGRYAFVLLVILFLALISSLFEAYLSPVLMEKLTSRLF
What is the function of this protein?
Required for complete septum migration and engulfment of the forespore compartment during sporulation.  Required for stabilizing and recruiting of SpoIIP to the septal membrane.
What are the official names of this protein?
Stage II sporulation protein M.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the sporulation septum and to the second division site within the mother cell. Before the start of engulfment localizes to the septal midpoint, then spreads throughout the septum prior to becoming enriched at the leading edge of the engulfing membrane, where it remains until the completion of membrane migration. Some remain partially trapped at the septum during engulfment and upon completion of engulfment become dispersed in the outer forespore membrane. Localization of the MPD complex to the septal membrane is dependent on SpoIIB.
Protein: ATPG_PHOV8
Sequence: MASLKEVKGRIASVNNTRKITSAMKMVASAKLHKAQAAIENMLPYERRLNHILTNFLSADSEVESPFIVKREVKRVAIVVFASNTSLCGGFNANIIRHLTVILDEYKSLGMENVLLYPVGRKVAEGVKKLGFKAEGDFQHMADKPSYQEAAALAEDLMRRFLHRDIDKVELLYNHFRSTAVQVLTRETYLPIDLTQEKKEEDKGRIPDYIVEPSVDVVMGELLPKVLRMKMFTVLLDSNASEHAARTMAMQIATDNANDLLQDLTVMYNKSRQQAITNELLDIVGGSMA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LAM6_YEAST
Sequence: MWGDSMRELGDAMDNELNAVKPVVEEGGMDGARKFIKGKSFQKSSTEHMLISPGRDGSVPLNGLKSSPADPHLSDVNSILDNHRGGGETALTSVNNIIMATSTNGDSDGVDGDAKRPSISNCSSRSSFFDTVLSTFSLKSNSQDTVTNEVKNIEVQFASEEANKKFRQMFKPLAPNTRLITDYFCYFHREFPYQGRIYLSNTHLCFNSTVLNWMAKLQIPLNEIKYLDKVTTNSSAISVETVTNRYTFSGFIARDEVFQLITRVWSKENLTNINDVLEVDERVSKKKGISSTPSSIFNNVSTNAYNDFISTTTTEPTSRASYMSENDMLIEEAIRSVDDYMGTPRASPSSSSSSSSSSSSLGSSTTYYCRPVYRLKPNAPFQYEGPFHVQETMDFPYKPEANNEYVLLERQFSVPPGLLFIMMFNEDNPVFELSFLKTQDSSNISHIGTFEKVNKDGQHYREFQYTKQLHFPVGPKSTNCEVAEILLHCDWERYINVLSITRTPNVPSGTSFSTRTRYMFRWDDQGQGCILKISFWVDWNASSWIKPMVESNCKNGQISATKDLVKLVEEFVEKYVELSKEKADTLKPLPSVTSFGSPRKVAAPELTMVQPESKPEAEAEISEIGSDRWRFNWVNIIILVLLVLNLLYLMKLNKKMDKLTNLMTHKDEVVAHATLLDIPAKVQWSRPRRGDVL
What is the function of this protein?
Involved in regulation of various organellar membrane contact sites (PubMed:26119743).  May be involved in sterol transfer between intracellular membranes (PubMed:26001273).  Selectively transports sterols between membranes in vitro.  Involved in stress-dependent formation of sterol-enriched vacuolar membrane domains (PubMed:25987606).
What are the official names of this protein?
Membrane-anchored lipid-binding protein LAM6, Lipid transfer at contact site protein 1, Lipid transfer protein anchored at membrane contact sites 1.
What is the protein family that this protein belongs to?
Belongs to the YSP2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Localizes to intracellular puncta representing endoplasmic reticulum-mitochondrion membrane contact sites (ERMES), nucleus-vacuole junctions (NVJ) and vacuole-mitochondria patches (vCLAMP) (PubMed:14562095, PubMed:26119743, PubMed:26001273, PubMed:25987606). Localization to ER-mitochondria contacts is dependent on TOM70/TOM71, and localization to ER-vacuole junctions on VAC8 (PubMed:25987606).
Protein: THIC_MAGSA
Sequence: MSETTLKITTGPLPGSRKIYVEGSRPDVRVAMREIDLTPGSGEAPVRVYDCSGPYTDPSMQVDITKGVPRLREQWILERGDVEHYEGRAHKPEDDGLKPGETIGVPVFDRAGAGLRPLRAKPGKAPTQLAYARAGIITPEMEYVAIRENMKRAEMKAAVVRDGEDFGADIPDEVTPEFVRAEIARGRAVLPANVNHPEAEPMIIGRNFLTKINANIGNSAVASSVDEEVEKMVWATRWGADTVMDLSTGRHIHATREWIIRNSPVPIGTVPIYQALEKVDGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYIPLTAKRTTGIVSRGGSIMAKWCLAHHKENFLYTHFEEICELLKAYDVGFSLGDGLRPGSIADANDAAQFGELETLGELTHKAWAHDCQVIIEGPGHVPMHKIKKNVEKQIELCGEAPFYTLGPLVTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDKQDVREGVVTYKLAAHAADLAKGHPGAQVRDNALSRARFEFRWKDQFNLSLDPEKALAFHDQHLPAEGAKLAHFCSMCGPKFCSMKISQEVRDFAAAEQGMAEMSEKFVNDGAEIYHTEPAQAQQAKPAAE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PDXT_ACIC1
Sequence: MTIPSNRPRVGVLALQGDVREHLAALGDAGADAVPVRRADELATVDALVIPGGESTTMDKLARAFGLWEPLRARLAAGMPAFGSCAGMIMLAARVVDAAPGQETLGVLDITVRRNAFGRQVDSFEADIPLTGLDGGPLRAVFIRAPWVEETGPDVEVLGRVPSGRHAGRIVAVRQGAVLATAFHPELTADRRLHAFFVAMVAAQARV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RK16_PSINU
Sequence: MLSPKRTRFRKQHRGRMKGVSTRGNRICFGKFALQALEPAWITARQIEAGRRVIARYARRGGKMWIRIFPDKPITMRPAETRMGSGKGSPEYWVAVVKKGRILYEINGVSEKMAQAAMKIAAHKMPIHTKFITLSQLTNG
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y78A_METJA
Sequence: MKVEILHKTPKGFLIARGKREIKIGSVVIFKNKKIGKVVDIFGPVAKPYIKILPINKDIEVSGTAYIKNDKSKYKNTEKKN
What are the official names of this protein?
Uncharacterized protein MJ0782.1.
What is the protein family that this protein belongs to?
To M.thermoautotrophicum MTH886.
Protein: FLGI2_HAHCH
Sequence: MHEVSDKTNAIHPLQRVSRALFALGLLCFAAMAGAERIKDIATVEGVRSNQIVGYGLVVGLDGTGDKAPFTDQTFRNMMNRFGITIPAGTDPKLKNVAAVSVHADLPAFSKPGQKIDITVSSVGNAKSLRGGSLLMTNLKGADGKTYAVAQGNLVVGGFGAGGADGSSITVNVPSVGRIPNGATVERAVPSSFSHGDTLTLNLSSPDFTTAKRVQDRINDLLGPGLAQAVDAASIRVMAPREASQRVGFLSILENLEVEPGQEAAKIVINSRTGTIVVGQNVKVLPAAVTHGNLTVTITEDFGVSQPNALAGGDTVVVPQTDVNVEQEPSRMFKFGPAATLNDIVRAVNQVGAAPGDVMAVLEALKQAGALKAELIVI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein 2, Basal body P-ring protein 2.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: GLT_DROME
Sequence: MKPLLLVLALCGAQVHAHSVGLRPDYNDYSDEDTRRDWLPEPLKPVPWQSETRYAQPQEAVVQAPEVGQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQPIGYQGRVNATVQSPNCAQFPELDRLRLSESRGENVDDCLTLDIYAPEGANQLPVLVFVHGEMLFDGGSEEAQPDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNSSLALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTAPPSEHRLWKQWALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASRLNPLDRSLSRALVTMWVNFATTGVPNPSSGVWPQATSEYGPFLRFTNNQQSPLELDPHFGEGIYLPNYRVIYKPTTNFSPPITTTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQQEFIREREQRRREQQLRDQQRYPQQEPREQQDERIRQQREQEERLRQQREQEERLRQQRELEERIRQQQEREQYEREQQEREQREREELERQQREREQQQPEQQPEYNPEPVNPWGYPVQEPQPDDNPEDGRLPYPSYEQYGPEGNENLPETDANRNFSEEDREQQQQEQLRREQQEQQEREYQLQLEREQQEREQQERGQQEPGPEEYPSYEEYSRALQEKNAERDRIYAEEQERERQQQETLLQENQQHPEQSLPEEQPTHPNYEAYDGDRSYAEEQEREQQRRDQVEQEREEQPDEDQGEEYERSPDEEEAAEQDVLKVEDFPSYEAYLEAATKLREEQEEQEKLEEERYRAQQEEEDRIQAERERNSRN
What is the function of this protein?
Not known.  Binds calcium ions.
What are the official names of this protein?
Glutactin.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: GLGA_SHIFL
Sequence: MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHVHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKSQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: MIH_METMG
Sequence: MMSRTESRYSSQRTWLLSMVVLAALWSISVQRATARVINDDCPNLIGNRDLYKRVEWICEDCSNIFRNTGMATLCRKNCFFNEDFLWCVYATERTEEMSQLRQWVGILGAGRE
What is the function of this protein?
Inhibits Y-organs where molting hormone (ecdysteroid) is secreted.  A molting cycle is initiated when MIH secretion diminishes or stops (By similarity).
What are the official names of this protein?
Molt-inhibiting hormone, MIH.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: KARG_LIMPO
Sequence: MVDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKEWGDINTLVDLDPGGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphoryl group of ATP to L-arginine.
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_HALHL
Sequence: MIARLRGTLLEKRPPTLVVEANGLGYEVEAPLSTIEALPETGREVILHTHLSVREDGQTLFGFRTRAERDLFRRLIRVSGVGPKLGLALLSGVDGEELVRCVRDDDPKRLTQVPGIGRKTAERLIVELRDRLDGVGGGSTAAPAAGADHPTGENDPVSEAIEGLVALGYKPPEAARMARNAAEPELGCEAIIRRALQRAVPRGG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TRT8_ASPTN
Sequence: MSVYRLFTVSIMDMCVLKANCKDPLGFTVEYTCVFGISSPIPGLHGGEHVNSYGEGVCVITFHNKDGRVFWFIIEKLPKKYTYPISPRFTPQDASEFCGRLADVHVFNDVTVGHLWRNRTVVSMNALEEGLLSTWSFERMVLLGDSVHKMTPNIGQGANTAIEDAAALASLIHQMINPMTPQNASKAAIGHLFQKFQDLRMSRVQSTVQRAHFGARFHTRDDHLKALVGRYIFPYVGNLVMARTVKVIGGGHKIEFLPPPKRSMPWTAQTDHSQHKMHGSKVLWAYLSHPDQHWSDDPRGTAQLRSQSLGTHRTSTVGRTLFIELVIVMIDVVYARQDIGEDVNAGVKDMAVQSRNSMRFLPYVLSYGSTESLLAAGWRQVWVFRLLSYLFGALLGL
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of terretonin, a fungal meroterpenoid that acts as a mycotoxin (PubMed:22549923, PubMed:23116177, PubMed:25671343).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase trt4 (PubMed:22549923, PubMed:23116177).  DMOA is then prenylated into farnesyl-DMOA by the polyprenyl transferase trt2 (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Methylation by the methyltransferase trt5 then leads to farnesyl-DMOA methyl ester which is further subject to epoxidation by the FAD-dependent monooxygenase trt8 to yield epoxyfarnesyl-DMOA methyl ester (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Cyclization of epoxyfarnesyl-DMOA methyl ester by the terpene cyclase trt1 leads to a tetracycle intermediate which is in turn converted to preterretonin (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Dehydrogenase trt9 comes next to transform preterretonin to preterrenoid (PubMed:22549923, PubMed:23116177).  The FAD-dependent monooxygenase trt3 is then required for the C-hydroxylation at C16 of preterrenoid to yield terrenoid (PubMed:22549923, PubMed:23116177).  The cytochrome P450 trt6 catalyzes three successive oxidations to transform terrenoid into an unstable intermediate, which then undergoes the D-ring expansion and unusual rearrangement of the methoxy group to afford the core skeleton of terretonin (PubMed:25671343, PubMed:28759016).  Trt14 catalyzes the D-ring expansion of terretonin involving intramolecular methoxy rearrangement as well as the hydrolysis of the expanded D-ring and the methyl ester moiety (PubMed:25671343, PubMed:28759016).  Finally, the nonheme iron-dependent dioxygenase trt7 accomplishes the last two oxidation reactions steps to complete the biosynthesis of terretonin (PubMed:25671343).  Terretonin C is produced via spontaneous decarboxylation of the terretonin precursor (PubMed:23116177).  Another shunt product of the terretonin biosynthesis is dihydrofarnesyl-DMOA, derived from epoxyfarnesyl-DMOA through hydrolysis of the epoxide (PubMed:22549923, PubMed:22782788, PubMed:23116177).
What are the official names of this protein?
FAD-dependent monooxygenase trt8, Terretonin synthesis protein 8.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: SYL_CHLL3
Sequence: MKYDFSHTEKKWQAYWQEHGTFQAEEGQEKPKYYVLDMFPYPSGSGLHVGHLEGYTASDIVARYRRSRGNNVLHPMGWDAFGLPAEQYAIKTGTHPSLTTENNIRSFRETLQAMGFSYDWSREINTTDPGYFRWTQWIFLKLYEMGLAYQSEVDVNWCVELRAVLANEEVEEKIAEGLTVVRRPLRQWVLKITAYAERLLLDLDGLDWPENVKQMQRNWIGRSEGVEVDFELRCHRKMLRVYTTRPDTLFGATYLVISPEHPMAEKLATAPQLVEVKNYISKAKLKTELERTGLQKDKTGVFTGSYAINPANGEALPVWISDFVLTSYGTGAIMSVPAHDSRDWEFAKKFGLPIVEVVKSPHDVQDAVYEGKDSTAVNSSNSEISLDGLAFPEAFERMASWLELKKCGERKVNYRLRDWIFSRQRYWGEPIPVKHYEDGSLGTETDLPLRLPEVEAYQPTETGESPLANIPEWLYGTDGKGAFRRETNTMPQWAGSCWYYLRFIDPRNSEHLVDAEKEHYWMNVDLYIGGAEHAVLHLLYARFWHKVLYDLKVVSTKEPFQKLFNQGMILGEDGEKMSKSRGNVIPADHVLEKYGADAVRLYEMFLGPLEQVKPWNTNGIEGVSRFLNRVWRLVHPDTEGPAAVLDEAAMPGELLRRMHKTVKKVREDTECLKFNTAIAEMMVFVNDLHRTGNRNREAIETLVLLLAPYAPHISEELWEALGHPESIARAPFPTFDPALAANDVLTIAVQVNGKLRGTFEAAKDASKEEMLEAARAVESVRKFIEGSTVVKEIVVPGKLINFAVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XOAT5_ORYSJ
Sequence: MRIPRRKGGAGPLVGAPSRRAQVAAVFALALLLGVSVLYDSAHIAASLRRHGVGGGGSSGGGGGGGGDGARAYTNTKLSATTEEAEAEAAEVRSPPAQGVESAVEATDRGEAPPEQPVAADSGASSAETPPSLLEQVTETPPPSPSSSSAAAAAAEAQVGGDHGGESCDVYKGRWVYDEANAPLYKESACEFLTEQVTCMRNGRRDDDYQKWRWQPDGCDLPRFDAKLLLEKLRNKRLMFVGDSLNRNQWESMVCLVQSEAPWEKKSLVKNDSLNVFRLEEYNATIEFYWSPFLVESNSDDPNMHSIVDRIIKPTSIAKHAANWEGVDYLIFNTYIWWMNTPEMKILHGGSFSKKPVKYDEMERVAAYRKVLKTWSRWVEKHVDPKRSTVFFMSVSPVHMQSEGWGKPDAIKCFSETQPAINYTKKLEVGTDWDLFSTAHHVTKAMKRVPVHFINITALSEIRKDAHTSVNTLRQGKLLTKEQKANPRKFADCIHWCLPGLPDTWNEFIYGHIVSSPQRRPVEPIENQPQR
What is the function of this protein?
Xylan acetyltransferase required for 2-O- and 3-O-monoacetylation of xylosyl residues in xylan (PubMed:29569182).  Catalyzes the 2-O-acetylation of xylan, followed by nonenzymatic acetyl migration to the O-3 position, resulting in products that are monoacetylated at both O-2 and O-3 positions (By similarity).
What are the official names of this protein?
Xylan O-acetyltransferase 5, Protein trichome birefringence-like 13, OsTBL13.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: Y611_METJA
Sequence: MSIFRFSQREIIDLTISVLAIAFIFSYPNFSILVFIISLIAVGSGFIFHELMHRTVARKYGAWSEFRAWYEGLILGFILKLVFGATFIAPGAVYIYKDYLTPEENGKIALAGPLTNVALAFVFFILMLIFKPGSLLYWIGIFGFHINLFLAGFNMLPIPPFDGEKVLKWNPFIWAIVGLPLIGYMLYMMFW
What are the official names of this protein?
Putative zinc metalloprotease MJ0611.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDE6D_DROWI
Sequence: MGSDDLSAGDKIQKGFQINNMILRDADSGKIIWQENKDFSAPDVEHEARVPIKILDMRAVSREINFSTIESMENFRLDQKVLFKGRIMEEWFFEMGFVGANTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNETLITKSVVRLYYI
What are the official names of this protein?
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: IF2B_METMP
Sequence: MVDYFDYSSLLTRAREQLPEEVFKDVRFEIPSADSFVEGNRTIIKNFKDIAKFMERDPQEFAKYVMKELGTAGDMEGVRLILQGKFGWRMVNEKIQNYVNEYVLCPECGKPDTKIVKEGRIHFLKCTACGAMKPVKTL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.