PharMolix/UniProtQA huggingface dataset:
Protein: GLGC_PHOPR
Sequence: MGGVLGMILAGGEGSRLRPLTDSRTKPAVPFGGSYRLIDFALNNFVNADFLKIYVLTQFKSQSLYVHMKKGWNITGITDRFIDPIPAQMRMGKRWYDGTADAIYQNLSFIELAEPEHVCIFGSDHIYKMDIKQMLNFHKEKEAELTVSALRMPLSEASAFGVIEVDENGCMVGFEEKPTNPKSIPGDPENALVSMGNYIFNKDTLCTELEEDAAKEDSSHDFGKDIIPKLFPLGKVYVYDFTTNIIPGEKNTGYWRDVGTIEAYWQAHMDLLSEDAPFSLYNRQWQLHTHYPPLPPATILDSENSKVDINNCMISAGSYIRGAQIHKSILGFRTNVDHNTMISESVILGDVKIGANCSIRKAIIDKNVHIAPGTVIGENPEEDKKNYHVSDEGIVVIPKGAKIGY
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: BBX21_ARATH
Sequence: MKIRCDVCDKEEASVFCTADEASLCGGCDHQVHHANKLASKHLRFSLLYPSSSNTSSPLCDICQDKKALLFCQQDRAILCKDCDSSIHAANEHTKKHDRFLLTGVKLSATSSVYKPTSKSSSSSSSNQDFSVPGSSISNPPPLKKPLSAPPQSNKIQPFSKINGGDASVNQWGSTSTISEYLMDTLPGWHVEDFLDSSLPTYGFSKSGDDDGVLPYMEPEDDNNTKRNNNNNNNNNNNTVSLPSKNLGIWVPQIPQTLPSSYPNQYFSQDNNIQFGMYNKETSPEVVSFAPIQNMKQQGQNNKRWYDDGGFTVPQITPPPLSSNKKFRSFW
What is the function of this protein?
Transcription activator that acts as positive regulator of seedling photomorphogenesis (PubMed:17965270).  Acts downstream of COP1 and play an important role in early and long-term adjustment of the shade avoidance syndrome (SAS) responses in natural environments (PubMed:21070414).
What are the official names of this protein?
B-box zinc finger protein 21, AtBBX21, Protein LONG HYPOCOTYL UNDER SHADE, Protein SALT TOLERANCE HOMOLOG 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL3_BLOFL
Sequence: MDGLVGRKLGMTRIINEEGIMIAVTMIEILPHYVTQVKNKEKDGYCAVQVTTGNTRDKCLNKPKLGHLKKLGINYGKGLWEFRLNDSNRLISVGDIFTLKVLKCINKVDVTGISKGKGFAGAVKRWNFRTQDASHGNSLSHRAPGSIGQNQTPGKVFKGKKMAGHLGYEKATIQNLAVINIDIKNNLLLVKGAIPGVIGENVIVKRSVKIGYFKEMSSI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: AMY_ACASI
Sequence: MAHLLLAVVAITLALSQSVFGGSPYSNPHFTGSRSVITHLMQWKFDDIAAECERFLGPKGYGGIQLSPVNEHAVLGNRPWYELYQPVGYKIQSRSGNEEQFKGMVQRCNKVGVRIYVDIVMNHMSGAQEGHGNCWFKLQWHHDVSRCSLLVPNDFHGRESCHTDNMDIKNYDNPEEARNCRLSGLRDLKQSSEYVRQKQADFLNHLIDLGVAGSRSDASKHMWPGDLEAIYGKLHNLNTAYFPANSRPFIYHEVIYYGGDGIKSSDYTKLGRAIEFHFYRDIANVVRRHNQLKTVKNFGQPWGMVPSDDALVMVDSHDLQRFHTGQVGVNINYFESRLLKVATAFMLAWPYGVPRVMSSYHWDQKIEDGKDKNDWIGPPSDGSGNILSVTPQPDDTCNKEWICEHRWRQIYNMVHFRNVAGNEAVSHWWDNGDYQIAFGRGSKAFIAINLQDGQGLNRKLATGLPQGTYCDLVTGNLAGGKCTGGTVTVDGSGNADINIAKTAEDPFVAIHVEAKLH
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPD_GEMAT
Sequence: MAAGVQGESVARNYAEALLVLARKADDAEGWGALLRQVADAINNDVNLSRFLESPRIAAEQKSVVLSKALGDKVPHLFLRFLQQLVKNRRQMLIPAIATEYETLRDAASGIVHARVTVARETGDEEAKMIAERLSKATGKTVVPHFAVDPSILGGVVVRVGDTVMDGSLRRKLGMLRRRMGGTRA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KLDC2_MOUSE
Sequence: MADGNEDARAEDLPGPAFENYEAMELACPAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSADRGLQWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFAWSQPITTGKAPSPRAAHACATVGNKGFVFGGRYRDARMNDLHYLNLDTWEWNELIPQGVCPVGRSWHSLTPVSSDHLFLFGGFTTEKQPLSDAWTYCISKNEWIQFNHPYVEKPRLWHTACASDEGEVIVFGGCANNLLVHHRAAHSNEVLIFSVQPKSLVRLSLEAVICFKEMLANSWSCLPKHLLHSVNQRFGSNNTSGS
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.  The CRL2(KLHDC2) complex specifically recognizes proteins with a diglycine (Gly-Gly) at the C-terminus, leading to their ubiquitination and degradation.  The CRL2(KLHDC2) complex mediates ubiquitination and degradation of truncated SELENOK and SELENOS selenoproteins produced by failed UGA/Sec decoding, which end with a diglycine.  The CRL2(KLHDC2) complex also recognizes proteolytically cleaved proteins ending with Gly-Gly, such as the N-terminal fragment of USP1, leading to their degradation.  May also act as an indirect repressor of CREB3-mediated transcription by interfering with CREB3-DNA-binding.
What are the official names of this protein?
Kelch domain-containing protein 2, Endothelial differentiation inhibitory protein TNG.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCTN3_PIG
Sequence: MAGVTDVQRLQARLEELERWVYGPGGSRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYMDRIAIPDASKLQFILAEEQFILSQVALLEQVEALVPMLDSAHIKAVPEHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAAKQVKPAEE
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:33734450, PubMed:36071160).  Together with dynein is involved in spindle assembly and cytokinesis (By similarity).
What are the official names of this protein?
Dynactin subunit 3.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunit 3 family.
Protein: VAB2_KLULA
Sequence: MSFLFYGDSKHLRKRESFHFATIEKSDYSKQLQSLPLLPSSSSLRQDHIFSNVAKEVNQISDDVAIIYSRLQEEIDTEQSQTKEVNNKINHSVKKLESSFSKLVKLRSKFTKDSDKQLKQFESKYSDIDKKVRIIRDVNEELLDYVTRNGSIKVDATQFSKISKLLQERFPESSNTTETEANKDNSGQSQNEANSESLNSSYSRQSTNGSQNNAKKDYHSTKGNSADSNTTKSYRQSISSAPLALSSIRSTSRPSIATTLEHICITEPFTRPRGMSKSADL
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit VAB2, BLOC-1 subunit VAB2.
What is the protein family that this protein belongs to?
Belongs to the VAB2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Vacuole. Cytoplasm.
Protein: RL27_DEHMB
Sequence: MAHKKGAGSTKNGRDSKPKMLGVKRFAGEKVNSGTIIVRQRGTHIHPGENVGLGRDYTIFATCEGVVKFEPTTNDRRKVSVVAD
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: REX_SOLM1
Sequence: MKSEHIPKATIKRLAMYVQVLETLKREGSQVVSSELLARTCSVNPSQIRKDLAYFGEFGVRGVGYHVQDLIYSIKHSLGVDRVWKCALVGIGNLGKALLRHQDFKFRGFDIVGAFDCDPFKIGEEISGLEVVCTRRLKDAVKELGIEIGLITTPVNRAQRATNFLIEAGVKGIINYSPAMLTVPPDVYVEYVDFFHHFYSVAFSITLDRHQDRMGGDEDD
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAF15_RAT
Sequence: MVRTKANYVPGAYRKVVASQAPRKVLGSSTFVTNSSGSSRKAENKYAGGNPVCVRPTPKWQKGIGEFFRLSPKDSKKENQIPEEAGSSGLGKAKRKACPLQPDHRDDENE
What is the function of this protein?
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication.  Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions.  Also acts as a regulator of centrosome number (By similarity).
What are the official names of this protein?
PCNA-associated factor, HCV NS5A-transactivated protein 9 homolog, PCNA-associated factor of 15 kDa, PAF15, p15PAF, PCNA-clamp-associated factor.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Following DNA damage, localizes to DNA damage sites. Colocalizes with centrosomes in perinuclear region.
Protein: NOC_BACP2
Sequence: MKHSLSRFFGLGDKEHPERETEIEAEIAEHDTLKEEIQELPVDTIMPNRFQPRTIFSEEKIHELATTIHTHGIIQPIVVRPTEEEGKYELIAGERRWRAVQTLQWEKIPAIIKDFTDTETASVALIENLQREELSAIEEAHAYARLLELHDLTQEALAQRLGKGQSTVANKLRLLKLPEEVQQAILEKKISERHARSLVPLKLPELQIALLQEIIEKQLNVKQTEERVVKMLEQKTDRKPRPKRKAFSRDTRIAMNTIRQSLHMVEDSGLKINTEEEEFEEYIQLTIRIPK
What is the function of this protein?
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle.  It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
What are the official names of this protein?
Nucleoid occlusion protein, Noc.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HSLU_SALA4
Sequence: MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQAEQQQEPSAARQTFRKKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGARRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPQ_YERP3
Sequence: METLASLYNEHLSTLQQRTRDVLERHQLDALLIHSGELQRLFLDDRDYPFKVNPQFKAWVPVTEVPNCWLWVDGVNTPKLWFYSPVDYWHSVEPLPDSFWTKNIDVQPLLNADDIAQQLPVQRERVAYIGYAQQRAQALGFSAENINPQPVLDYLHYYRSYKTDYELACMREAQKTAVVGHRAAYEAFQSGMSEFDINLAYLMATGHRDTDVPYDNIVALNEHSAVLHYTILQHQPPAEIRSFLIDAGAEYNGYAADLTRTYAADRDSDFAALISDLNTEQLALIDTIKSGERYTDYHVQMHQRIAKLLRTHNLVTGISEEAMVEQGITCPFLPHGLGHPLGLQVHDTAGFMQDDKGTNLNAPSKYPYLRCTRVLQPRMVLTIEPGLYFIDSLLAPWRIGEFSKHFNWDRIDALKPYGGIRIEDNIVIHDKRVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: APTH1_SCHPO
Sequence: MTAKLNSVIINPSVAHTATVIFLHGLGDSGQGWSFMANTWSNFKHIKWIFPNAPSIPVTVNNGMKMPAWYDIYSFADMKREDENGILRSAGQLHELIDAELALGIPSDRILIGGFSQGCMVSLYAGLTYPKRLAGIMGHSGFLPLASKFPSALSRVAKEIPILLTYMTEDPIVPSVLSSASAKYLINNLQLKCLDRPFEGDAHSLSSESFMAMYKFTQTVIGSP
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates.  Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins.  Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
What are the official names of this protein?
Acyl-protein thioesterase 1, Palmitoyl-protein hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TX32_ANDCR
Sequence: ADVPGNYPLNTYGNMYYCTILGENEFCKKICKVHGVSYGYCYNSYCWCEYLEGKDINIWDAVKNHCTNTNLYPNGK
What is the function of this protein?
Binds to sodium channels (Nav) and affects the channel activation process.
What are the official names of this protein?
Toxin Acra III-2.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1799_STRPC
Sequence: MLTFLIPTAKEMVIPKESYPHLLPQPSQAILKAMAAMTTEDLAKSYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQVYITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSSEFDDVFSKDCKQLWISPKFMAEKEGRFKTHSTISKKARGAFLTACMENNCQTVDSLKSLVFAGFYYHPDLSTDHEFVYIKKEA
What are the official names of this protein?
UPF0246 protein MGAS9429_Spy1799.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: MUKF_VIBCH
Sequence: MSEFTQDTVQKPIDELVTWVKQYDFSLNLPTERLAFLLAIAVLSNERFDEELGEGELHDAFAIVTRLFAESGEASAFRANNAINDLVKQRLLSRFTSEMTEGASIYRLTPLAIGITDYYVRHREFSKLKLSIQLSMVADEMAKAVESAQQGGSVAHWRKNVFGVLKYSVSEIFDRIDLNQRVMDEQQQSVKEQIADLLNKDWRDAINNCEALLSETSATLRELQDTLQAAGDELQTQILDIQECVYGDLELDFIEETLSALQMKLDRITSWGQQSIDLWIGYDRHVHKFIRTAIDMDQNRAFSQRLRQSMNDYFEQPWYLTYADAERLSDLRDETLTLRDEEVTGHVPTEVEYEELQQVNDELAQRIGDMLKVHKEQGAAIDLALVLRDYLASHPRTHHFDLARMVVDQAVRLGYSESDYRAIQPDWTAINDFGAKVQANVIDRY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: DBF4B_XENLA
Sequence: MASVISVLHGQVMQQDDEPPLAKRRRCREITFAGKSFYLDVPANRQTQLLTKAIGRLGGIIESFLSRDVDYVVTGSKKAVASVSSVATRRGEKSQIQAAERKEPIHCSRGKQLLKKVVHSQECNSVLTNARSWGVTVLYVEDVVSYIERLERPPSRGIQNKTAEGRAADSTRPSLKIARLRSPFIKIEDQSRKFRPLQCTFTSFPELSFVCSDKSPFETVQTVKKKDPGDQEEEEGQRSQKPQARKRKGYCECCEETFDTLSEHLVGEHHFRFVSNPLSYKMIDDLAAQLTCDLMELPFGSPTSPEAERSSQNEDWDLDLAPGEAEPAGNEGHELGILKATRLDKDGHADCEDQGAPAYLRDGGAEEPDQRCGEIPLANIEVDVYNVCSFDQPVVTCTMELPDVSAEGKIHSNLLGSTVGDERVLQRTNGTCEPHIDLALGNGRELKHAELQKDPLTKDSQPELLSTAHEQLPTSAPCMLLEGASVVHFPSHGGTVGSQGDVTSHSAANKPHTENCPVDSTGDRHAQPAGSDALAMSCVIPTLDNGGRHVDATMQSHWEVPLGCTTDTLLSYSTTVTVGELGPEAHNPTPEQQPLLISTCSSITTVCCTDTEFKSCTVSVHSTSHSPPNQNVKSNQTPSLLEMDLANPNCHRAKRKHWDSLLSPPGKKPTSPSHCQSLTLPMWLLCQFPNYGQQVQLPVWADLCKWDGTAAAEEGTVDCSSSSTLPKLHQDSFSSESDWDAHLPSFFQNNPQQSLQCGDLRTAQVTLNESWYGKQLCNILTHDP
What is the function of this protein?
Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation.  Specifically required during the initiation of DNA replication in egg and during early embryonic development.  The complex cdc7-dbf4b phosphorylates mcm2 and mcm4 subunits and is required for cdc45 loading.
What are the official names of this protein?
Protein DBF4 homolog B, Dbf4-related factor 1, XDrf1.
What are the subcellular locations of this protein?
Nucleus. Note=Binding of complex to chromatin is dependent on pre-replication complex assembly but is not regulated by ATR checkpoint pathways.
Protein: LFTR_CERSK
Sequence: MRPPALTPRLLLRAYALGIFPMAESRDDPEIHWIDPRHRGIFPLDEFHISRSLARRIRRMDWRVGVNEDFAATVEACADREETWINPTIFRLYVELHALGHAHSLEVREGETLVGGVYGVTLGRAFFGESMFSRRTDASKVALAFLIDRLRAGGFTLFDTQFLTPHLASLGAIEIRRSDYHQRLTEALAGNASFTPEGYWADPASVVQRNSQTS
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAT_DESAL
Sequence: MSNLIPPHGGKGLVCCLLEGAELEAEKKKAATLPKLNISSRAKGDLIMMGIGGFSPLDGFMTKADWKGVCEDFLLADGTFWPIPVTLDASADDAAKINVGDEIALFDPEREEFMATMKVTEKYEMTEADKIFECEKVFMGEGTPTAEEFWKIAKDDHPGVQMVMNQGEFNLAGPVKVLSEAEYPEEYPGIYQRPAESRAIFEERGWKEIAAMQLRNPMHRSHEYLCKIAIEVCDGCFIHSLIGNLKPGDIPADVRVKCIDALVKNYFVEDKAVQGGYPLDMRYAGPREGLLHATFRQNYGCSRMIIGRDHAGVGDFYGMFEAQTIFDKIPTPEGEGKALLCTPLKIDWTFYCYKCDGMASLRTCPHAKEDRVLLSGTMLRKMLSEGGELPDHFGRDEVVAILREYYEGLTEKVEVKLHGAATGN
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: RSMG_LACAC
Sequence: MNPEEFILELSKHNFELSDKQKQQFKLYFKYLIEVNEHVNLTRITEENEVYLKHFFDSVTPLFTFGEVFKDGATLCDVGAGAGFPSIPLKILNPTLKVTIVDSLAKRLTFLKNLIEKLGLTDVELVHGRAEDVGQNKLYREKFDLVTARAVARMSVLSEYCLPLVKKGGYFIALKGPKAEDELDDGQKALEVLGGKLVKEEELTLPHSKEERTLILVKKIKQTPKKYPRQAGTPRRKPIH
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN410_BOVIN
Sequence: MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDDTPNHTNSSKEVPSSAVLRSLQVNVGPDGEETRAQTVQKSPEFLSTPESPSLLQDLQPSDSTSFILLNLTRAGLGSSAEHLVFVQDEADDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTSSNGENVHLGSGDGQPKDSGPLPQMEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAAGCGKSFYVLQRLKVHMRTHNGEKPFVCPESNCGKQFTTAGNLKNHLRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQMGAAGSQEQEPAAEPLMGSSLLEEASVTSKNLVSMNSQPSLGGESLNLPNTNSILGVDDEVLAEGSPRPLSSVPDVTHHLVTMQSGRQSYELLNQGDLTERRT
What is the function of this protein?
Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3', and is specifically required to silence expression of fetal hemoglobin in adult erythroid cells.  Prevents expression of fetal hemoglobin genes HBG1 and HBG2 through CHD4: acts as a direct transcriptional activator of CHD4, a central component of the NuRD complex that represses transcription of fetal hemoglobin genes HBG1 and HBG2 in erythroid cells.  May also activate transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence.  May activate transcription of the gap junction gene GJC1, perhaps in response to increasing glucose.  However, recent studies suggest that ZNF410 is dedicated to regulate expression of a single gene: CHD4.
What are the official names of this protein?
Zinc finger protein 410.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Directly binds to the sequence motif 5'-CATCCCATAATA-3'.
Protein: RXLT1_MOUSE
Sequence: MRLTRTRLCSLLVALYCLFSIYAAYHVFFGRRRRPLGTTSRNSRKAAAAQAKERRGREQSALESEEWNPWEGDEKNEQRHRVKTNLQILNKSTKEKIEHRVQIWGKAAIGLYLWEHIFEGTLDPADVTAQWREGQSVVGRTHYSFITGPAVVPGYFSIDVDNVVLVLNGREKAKIFHATQWLIYAQNLMKTQKLQHLAVVLLGNEHCENDWIMQFLKRNGGFVDLLFITYDSPWINGADILQWPLGVATYRQFPVVEASWTMLHDERPYICNFLGTAYENSSRQALMNILKQDGNDKLCWVSAREQWQPQETNESLKNYQDALLHSDLTLCPVGVNTECYRIYEACSFGSIPVVEDVMTAGHCGNTTSQHSAPLQLLKAMGAPFIFIKNWKELPAILEKEKTISLQEKIQRRKVLLHWYQHFKTELKWKFTKILESSFFINNKV
What is the function of this protein?
Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan.  Participates in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.
What are the official names of this protein?
Ribitol-5-phosphate xylosyltransferase 1, Transmembrane protein 5, UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RXYLT1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: FPG_LACAC
Sequence: MPEMPEVETVRRTLLPLIKGKTIEKVVLWYPTIVATDHDEFLKELPGKKIIGIDRYAKYLLIRLSDNLTIVSHLRMEGKYHLTTEDAPKDKHDHVEFVFTDKTALRYNDVRKFGRMQLIITGTERQVTGIKKLGPEPNTSEFSQQYLIDNLKKKHKNIKNVLLDQTTVAGLGNIYVDETLWQSKIHPLSIANKIPAKKVAGLWENINQTIALAIEKRGTTVHSYLDANGEVGGYQEMLQVYGHVGEECPRCGNIFEKIKVSGRGTTFCPHCQVIYK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.