PharMolix/UniProtQA huggingface dataset:
Protein: C71Z6_PASSA
Sequence: MDPVVIFLVLAFPIASVYLLFYHKKRVGGLSSPPGPRGLPFIGNFFQLYKAPCIHEYLWNLSKKYGSLMTLHMGSVPILVVSSPKMAKEVLKTQDLIYCSRPRMTGMRKLSYDGLDVAFSTYSEHWRHVRKLCTLELFTQKRAQLCFRLVHEQEVSRMIVRLSETAAASKDVNAFECFSNLSTSIISRVAFGKRYDEDGIGKERLQRMLSEIDAMLAGIFVSDFFPMFGWIDRLSGMRARLDRTFKEMDMFYEELIDEHLKPNRPESPTEDLIDVMLKNKGSSCLLTMDSIKAILLNVFNGGTGTSATLLVWAMTALMRNQGVMKKAQEDIRRVIGRKGNVDEDDIQNLSYLRAVVKETMRLYPTGPLLIPRETMESSIIGEDKDHMYMIKPKTLVYVSMWAIGRDPEIWKNPMEFVPERFLERPDLNYKGQQFEYIPFGAGRRICAGIHLGVTTVELALANLLYTFDWEPPAGTRFEDIDDETLNGLTLQKKNALYIRPKKYICP
What is the function of this protein?
Involved in the biosynthesis of coumarins and furanocoumarins (FCs), natural products required for defense responses against attacks by predators with potential medical and agroindustrial usages such as anticoagulant, rodenticide and artificial vanilla substitutes (PubMed:29971079).  Catalyzes the conversion of xanthotoxin into 5-hydroxyxanthotoxin (PubMed:29971079).
What are the official names of this protein?
5-OH-xanthotoxin synthase, Cytochrome P450 CYP71AZ6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.
Protein: RPOB_ACIF2
Sequence: MAYSFTEKKRIRKDFGKSQSILAVPYLLATQMDSYREFLQESVPPAARKETGLEAVFRSVFPMESYSGNAMLDYVSYRLEKPVFDVVECRQRGLTYCAGLRVRLRLAVMEKDDTTGAKRVKDVKEQDVYMGELPLMTEHGSFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLFNARIIPYRGSWLDFEFDPKDHVYARIDRRRKLPATTLLRALGYSTQDILEMFFDMETFRLIDGDLRYVLIPQRLQGEVAAFDIVSPETGDVLVQAGKRITVRQTKALSEVQGLHEIPVPDSFLLGKVVARDIVHPETGEVVVQANEPVSGELLDALRKMPSLTLHTLYLNELDRGPYISETLRIDTSRDAHDAQMEIYRLMRPGEPPTKDAAQNLFQGLFFSPDRYDLSAVGRMKFNRRVGRDEITGPGVLNDADIIAVLKVLVALRNGVGEIDDIDHLGNRRVRSVGELMENQFRLGLVRVERAVKDRLALAESEGLTPQDLINAKPIAAVVNEFFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLSCYARTNSYGFLETPYRRVVDRRTTDEVEYLSAIEEGNYMIAQANSTVDEHGVLTDELVSCRFKNEFTLANPDQVQFMDISPRQIVSVAASMIPFLEHDDANRALMGSNMQRQAVPTVRSDAPMVGTGMERVVAIDSGAAVVARRGGVVDIVDGARIVIRVSDEETLPEEPGVDIYNLVKYARSNQNTTLNQRPVVKVGDVVSRGDVLADGPSTEMGELALGQNILVAFMPWNGYNFEDSILISERVVAEDRYTTIHIEEFSVFARDTKLGPEEITRDIPNVAEGALRHLDESGIVVIGAELAPGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDNSMRMPAGMYGTVIDVQVFTRDGIEKDARAKSIEEHELARIRKDLNDQYRIVEEDSYQRIERQLIGKVAEGGPNGLAAGNKVTKAYLKDLPRAKWFEIRLRTEESNESLEQIRAQLEEQRQRLDAVLEEKRRKLTQGDDLSPGVLKMVKVHVAIKRHLQPGDKMAGRHGNKGVVSKIVPVEDMPYLADGTAVDIVLNPLGVPSRMNVGQILETHLGWAAKGLGKKIGAMLDSEVAMAEMRAFLAEIYNRSGKKEDLDSLTDQEIRELSANLRGGVPMATPVFDGASEEEIGDMLELAGLPRSGQVTLYDGRSGDAFDRPVTVGYLYMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVSGRSKMYESIVKGDFRMDAGMPESFNVLLKELRSLGIDIELEQSK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SYRM_RHIME
Sequence: MDQPTWKRPHRAKFAGVSDAAQQRQMPNLASIDLNLLVDLEALLQYRHITQAAQHVGRSQPAMSRALSRLRGMLKDDLLVAGSRGLVLTPLAECLTQMLPSVLDAIRQMMNLSLAPAQRRWKVTMAMPDHQAVVLLPHLLPRLHERAPHLDIVTDPLLGGALGLLEQGEIDVVVGQMGAAPLGYLRRRLYADSFTCVLRHNHPALAQEWTIEAFAALRHVAIASEPDELFGQIYDRLTKLGLQRGDPMVVSTVLTAAVLIAATDSVLVVPSRVATRVAAMLSLAVIPPPVELRPYEVALIWHERCHRDPEHRWLRGEIAAAASTAG
What is the function of this protein?
Acts in trans to stimulate nod gene expression via nodD3 and exo gene expression via SyrA.
What are the official names of this protein?
HTH-type transcriptional regulator SyrM, Symbiotic regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: AROA_STRAW
Sequence: MTVNPAHTALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASEPGWLRRPLRSRDTLLMAAALREMGVGIEETVSSSSSVGGGSDGSGEAWRVIPAALHGPATVDVGNAGTVMRFLPPVAALADGPIRFDGDPRSYERPLNGVIDALRALGARIDDDGRGALPLTVHGGGALDGGPVAIDASSSSQFVSALLLSGPRFNQGVEVRHTGSTLPSMPHIRMTVDMLRAVGAQVDTPESGGEANVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGKVVIPDWPERTTQPGDKLREIFTEMGGSCELTEQGLEFTGSGAVHGIDVDLSEVGELTPGIAAVAALADSPSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLSIRPRRLHGGIFHTYDDHRMATAGAIIGLAVDGVQIENVATTAKTLPDFPDLWTGMLGN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LITP_PHYSA
Sequence: MSAVPFTRVLLISGFLAHLLLSTFVTLTVCKEVTEESDDLSKRNVLQRQLWAVGSFMGKKSLENTNRRSDEDMEISALFRGSPLKVKRSD
What are the official names of this protein?
[Phe8]-phyllolitorin.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SL9A8_CHICK
Sequence: MAEFANASHEVINVTLGTTLAATTKLVMPTPAKPILPVQTGVQAQQEEQSSGMTIFFSLLVLAICIILVHLLIKYRLHFLPESVAVVSLGIIMGAFIKIIEAQKLANWKEEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFSVFGTAISAFIVGGGIYFLGQADVIYKLNMTDSFAFGSLISAVDPVATIAIFNALNVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRENMSDVSGWQTFLQALGYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFMCETCVFAFLGLSIFSFPHKFEMSFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLGLEPIEKRQLIGTTTIIIVLFTVLLLGGGTMPLIRLIGIEDSKARKRNKKDVNLSKTEKMGNTIESEHLSELTEGEYEAQYIKRQDLKGFMWLDAKYLNPFFTRRLTQEDLHHGRIQMKTLTNKWYEEVRQGPSGSEDDEQELL
What is the function of this protein?
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions.  Major proton extruding system driven by the inward sodium ion chemical gradient.  Plays an important role in signal transduction (By similarity).
What are the official names of this protein?
Sodium/hydrogen exchanger 8, Na(+)/H(+) exchanger 8, NHE-8, Solute carrier family 9 member 8.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: YPI1_PICST
Sequence: MSNRTSNTTVEPRGSEVENRENVLLLRRQSVPEHESNPQERTKATQKKKKKKPKVRWTEDVVDNEDMNKKKTKICCIFHPQRNFDDGTDSDHSHSDSDSSSDSSGDERGGHEGSSRGPDGGNDSKKIVDGVKKEPIPNAYEYQPVYKNESKLPPGINDER
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
What are the official names of this protein?
Type 1 phosphatases regulator YPI1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALG6_YEAST
Sequence: MAIGKRLLVNKPAEESFYASPMYDFLYPFRPVGNQWLPEYIIFVCAVILRCTIGLGPYSGKGSPPLYGDFEAQRHWMEITQHLPLSKWYWYDLQYWGLDYPPLTAFHSYLLGLIGSFFNPSWFALEKSRGFESPDNGLKTYMRSTVIISDILFYFPAVIYFTKWLGRYRNQSPIGQSIAASAILFQPSLMLIDHGHFQYNSVMLGLTAYAINNLLDEYYAMAAVCFVLSICFKQMALYYAPIFFAYLLSRSLLFPKFNIARLTVIAFATLATFAIIFAPLYFLGGGLKNIHQCIHRIFPFARGIFEDKVANFWCVTNVFVKYKERFTIQQLQLYSLIATVIGFLPAMIMTLLHPKKHLLPYVLIACSMSFFLFSFQVHEKTILIPLLPITLLYSSTDWNVLSLVSWINNVALFTLWPLLKKDGLHLQYAVSFLLSNWLIGNFSFITPRFLPKSLTPGPSISSINSDYRRRSLLPYNVVWKSFIIGTYIAMGFYHFLDQFVAPPSKYPDLWVLLNCAVGFICFSIFWLWSYYKIFTSGSKSMKDL
What is the function of this protein?
Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 6, Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PBP2_YEAST
Sequence: MSTETTKPSITTTPTTVLVSPNTLKRKKGEDTSEEQLEAEIKRVALKDADSHSDNDHDSPDNVPSDVHLRMLCLVKHASLIVGHKGATISRIKSETSARINISNNIRGVPERIVYVRGTCDDVAKAYGMIVRALLEEHGNEDNGEDIEISINLLIPHHLMGCIIGKRGSRLREIEDLSAAKLFASPNQLLLSNDRILTINGVPDAIHIATFYISQTLLNFQMESPQKNVKRSIYYQPTQFNSVLIDHSQPNTIFHQRNHQYHPSDKLLSYKPNKNLPISSTLLSMATPQYTTASVANATAFQPNFVIPNVTVLDGPVISPAPGNHLLMNFVQQEIFIDEKFVGNVIGKDGKHINSVKESTGCSIIIQDPVEGSSERRLTIRGTFMASQAAIMLISNKIEIDRSNAERKRRSPL
What are the official names of this protein?
PAB1-binding protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBIA_XANCP
Sequence: MSKQGFKNVPMAPALTWPERLGQYWKLVRGDRPIGSLLLLWPTWWALWLAAGGLPPLWTLFVFTAGVWLTRSAGCVINDYADRWLDPHVERTKSRPLATGAVSGREALWVFVVLMLVAFALVLSLNWLTVALSVPGLFLAASYPYLKRHTHLPQVYLGMAFGWGIPMGFAAVQGSVPLLAWLLYAANILWATAYDTWYAMVDREDDLRMGSKSTAILFGRYDLIAQGVLYALMFAALVLVGLRAGLSIAYWAGLGIAALLVAYEFHIARHRERGPCFRAFLHNNWVGLAIFVGIAASLALR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SURA_PSESM
Sequence: MLGALLLSGAVHAAVQPLDSVVAIVDNDVIMKSQMDQRVREVQQTIAKRGSGVPPAADLQPQVLDRLILENLQLQMGERSGIRVSDDELNQAIGTIAQRNNMSVEQFRAALAHDGLSYEDAREQVRREMIISRVRQRRVAERIQVSEQEVKNFLASDQGKAQLSEEFHLANILIATPDSASSDAIQAAAVKAKSIYDQLKKGADFAKIAATTSSSENALEGGDMGWRKAAQLPPPFGDMLSSMPIGDVTPPARTPGGFIILKLLEKRGGQGQAQMRDEVHVRHILIKPSEIRSEEATKLLAQKIYERIENGEDFATLAKSFSEDPGSALNGGDLNWVDPNSLVPEFRDVMSSTPQGELSKPFKTAYGWHVLEVLGRRATDATGQARDQQALSVLRNRKYDEELQTWLRQIRDEAYVEIKLPGATQAAQ
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: PUR9_STAS1
Sequence: MKKAILSVSNKAGIVTFGQSLIEQNYELYSTGGTMRELANGGLPVKSISELTEFEEIMDGRVKTLHPSVHGGILADRDKPEHLEQLQAQGIDLIDMVVVNLYPFKETVANPNVTEEDAIENIDIGGPTMLRAAAKNFKHVITVVHPADYNEVIDKLKNGTLDEAYRKSLMIKVFEHTNEYDAAIVDYFKDNKESLRYGENPQQSAYFVRTSDAKHTLAGAKQLHGKQLSYNNIKDADAALSLVKQFEQPAAVAVKHMNPCGVGVAETIDEAYKHAFDADNQSIFGGIVALNRTVEKSLAEVLHGIFLEVVIAPKFTQEALEVLGKKKNIRLLEIDMTIDNSEQELVSVSGGYLVQDKDNVKLNREDMTVVTEVEPTEAQWDAMLLGWKVVASVKSNAVILSNAKQTVGIGAGQMNRVGSAQIAIERAIEINDDVAMVSDGFFPMDDTVELAANSGIKAIIQPGGSIKDQESIDMANKHGIAMVTTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: NADK_METKA
Sequence: MFRPQVVGVTGRTDLGRAVRVAERVCRLCDREGFEVLVDDSLGIGEYPRVNLKDMGKEVDMIITIGGDGTILRVSRITSEYEVPILGVNLGKFGFLTEVSESGLKEAVSRLARGDFNLEEHRKLRIKIGGSDEGDALNEVTVITSRPAKMIRYRLSIDGFELETTWADGVLVATPTGSTAYSLSAGGPIVEPQVECSIITPLNPFKLEARPMVVSMDRRVEIDVDDPERAEVVVDGQEYMNLDGTVSVTRSPNVARFIRFGSTYFERLKEKFLRWD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_FRATN
Sequence: MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKNLVTFQTDAEGQPVNSVGVFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQAREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQENAKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIFGGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PM2P5_HUMAN
Sequence: MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQPAKLTPRSTPPHPCSLEDNVITVFSSVKNGPGSSR
What are the official names of this protein?
Postmeiotic segregation increased 2-like protein 5, Postmeiotic segregation increased protein 4, Postmeiotic segregation increased protein 7, Putative postmeiotic segregation increased 2 pseudogene 5.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DER_ACIBT
Sequence: MKPVIALIGRPNVGKSTLFNQITKSRDALVADFAGLTRDRKYGDATYQNKSFIVVDTGGIGESEGGIDNYMAEQSKTAINEADIIIFVVDARAGLLASDEQIARELRTLGKKIYLVANKVDGVHAEAALVEFYKLGMGEPLQVAASHGRGVQQMLEDVLQDIPEDENPEEHDKDTGLRLAIIGRPNVGKSTLVNRLLGEDRVVAFDQPGTTRDSIYIPFEREGRKYTLIDTAGVRRKGKVDEMIEKFSIVKTLQAMKDAHVVVVVVDAREGIVEQDLHLIGYALEAGRAMVIAINKWDNMSEYDRKQCKLDVERRFDFIPWARIHLISALHGTGVGELYPSIHRAYESANLKVSPAKLTQILNDATDQHQPPTVQGRRIKMRYAHMGGQNPPTIVIHGNKVDKTPADYRRYLENVFRKVYKLEGTPVKIEFKTSENPFEGRKSQVDERTAARRRRYIQKFKKAEKKFKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ESXM_MYCMM
Sequence: MTARFMTDPHAMRDMAGRFEMHAQTVEDEARKMWASSQNIAGAGWSGMASATSLDTMGQMNTAFRNIVNMLHSVRDGLVRDANNYEQQEQASQQVLRG
What is the function of this protein?
Alters the host macrophage cytoskeleton and enhances macrophage motility (PubMed:36356582).  Promotes granuloma efflux, extrapulmonary dissemination of infection and bone disease (PubMed:36356582).
What are the official names of this protein?
ESAT-6-like protein EsxM, Type VII-secreted effector EsxM.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
Protein: VF329_ASFP4
Sequence: MLRVFIFFVFLGSGLTGRIKPQITCKYFISENNTWYKYNVTILNGTIVLPAYNTIPSNAAGISCTCHDIDYLQKNNISIHYNTSILKTFQDIRIIRCGMKNISEIAGGFGKELKFLDLRYNDLQVIEYNILRKLIRSNTPTYLYYNNLMCGKRNCPLYYFLLKQEQTYLKLLPQFFLRRINFSNNNTYLYHFLSCGNKPGHEFLEYQTKYCRTKFPEINITVNQLTAKKNTERYKSCYPLVFISILCSCISFLFLFICLLRSICKKYSCTKQGKSGHNYIPLIPSYTFSLKKHRHPETAVVEDHTTSANSPIVYIPTTEEKKVSCSRRK
What is the function of this protein?
Viral TLR3 homolog that probably prevents TLR3 dimerization and subsequent induction of IFN (By similarity).  Inhibits dsRNA-stimulated activation of NF-kB and IRF3 (By similarity).
What are the official names of this protein?
Transmembrane protein I329L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I329L family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein.
Protein: NGL2_YEAST
Sequence: MTQDKEVKVVAPDVAPDQEVEINKSVKDAKHQTNDDSLLQHKKKGKKGKKSKPIVTPEHIAKVRAEREVMRKAKRDAMLAQGVDPDCPPELHFIRRPFLSLHEAEPVTGFRFKLMTYNCLAQALIRRKLFPDSGDALKWYRRSKVLLNEFKYYNSDVICLQEIDHIQFQSFWKDEFSKLGYDGQYYRNATKNHGVAIMWRRELFHQVDKMLIDYDKESSESISTRTTTNNVGLVLALKFSEKVLSNLGKKSSKKCGILIGTTHLFWHPFGTYERTRQCYIVLKKMKEFMHRVNVLQNENDGDLSHWFPFFCGDFNSQPFDTPYLSMTSKPVHYRNRAKTVIGCSTSYKFSKVRDGEEGADDEEGGNIEKYGKDQPESPVPEKFHANEEQSELVDKMAQLHNSLDMRAISLYSVGYKNVHPENAGLDNDRGEPEISNWANTWRGLLDYLFYVKKWDPQSNCQEVETLGDFEKENKVKCRGFLRMPPGNEMTKHGQPHVGEYASDHLSMVCDLELQL
What is the function of this protein?
Involved in pre-rRNA processing.  Required for the final stage of 3'-end maturation of 5. 8S rRNA at site E.
What are the official names of this protein?
RNA exonuclease NGL2, Carbon catabolite repressor protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1378_STAAC
Sequence: MATWLAIIFIVAALILGLIGGFLLARKYMMDYLKKNPPINEEMLRMMMMQMGQKPSQKKINQMMTMMNKNMDQNMKSAKK
What are the official names of this protein?
UPF0154 protein SACOL1378.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IAAF_AROAE
Sequence: MDFDLTDEQRAIQDTFARFSDERIAPQAAALDEARAFPRALFRELAELGFFGMRYPESVGGSGLALSEFCLALSEVARGSMSLAGAVAMQSLMGTKFLQLLGNADIVERLFKPALRGDRIGAICMTEPNAGSDLESIATTATRVDGGYVINGQKTWITSAPVADFFTVFARAGDEKKLTIFLVEKDVPGITVGREIHKMGVWALPTSEVAFDGCFVPDSHRLSKEEGDGEGHLKKTLAEIRIITGAMALGVARAALFAAVRYAGERKQFGKPINRFQAIQLKLADMATGLEAATTLVHRAAWLCDMKRPHHKEAAMAKLFATETAAGICDDAARVLASYGYAMEYPVQRYLRDVRFTLIGGGTSEILKLVIAKEVSS
What is the function of this protein?
Involved in degradation of indoleacetate, the most common member of the auxin class of plant hormones (PubMed:34059946).  Catalyzes the irreversible oxidative decarboxylation of (2-aminobenzyl)malonyl-CoA to 2-aminocinnamoyl-CoA and CO(2) (Probable).  In vitro, shows high catalytic efficiency with benzylmalonyl-CoA, a chemical analog of the physiological substrate, but otherwise accepts only a few medium-chain alkylmalonyl-CoA compounds as alternative substrates with low activities (PubMed:34059946).
What are the official names of this protein?
Benzylmalonyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: ASSY_CARRP
Sequence: MKIKEKIVLAYSGGLDTSVIVKWLQNELNFEVITFTADLGQGEEILLAKKKAKLLNIKNIFVKNLKKEFIKNFVFPFLRSSSTYENNYLLGTAIARPLIVKELMKISYYLNTNYVSHGATGKGNDQIRFELGFKYFNPKIKIIAPWRIWNLNSRNSLLNFCIKNNIKFDSKTKKYSIDKNLFHNSYEGGNLDNINYEPDEPMWEHTLSNYNSLDYPIYISLTFKNGDPIKINNKNYNVEELFLKLNNLGSIAGIGRLDIIENRLIGIKSRGCYESPGASIIMYARKKLESLILDKEIYSFKEEIALKYSKLVYNGYWWSPERILLQKIIDYTQTSINGIIKLKIFKGQINIASINSINSLFNSKNSSFDEISNLFNQSDSSGFINIKSLRLII
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_THENN
Sequence: MNIKSAEFVDRVKIFVKAGDGGNGCVSFRREKYVPKGGPDGGDGGDGGFVFLRANPSLSTLIEFVNKRKFFAENGKHGMGKKMKGRNGRDLYIDVPVGTVVKDASTGQIIADLDEPGKVVCVARGGRGGRGNAHFSTPTRQAPLIAEKGEKGEARWLELELKILADVGLVGYPNVGKSSLIARISNARPKIANYPFTTLVPNLGVVKYGDFSFVVADIPGLIEGASEGVGLGNVFLRHVERCFVIVHMLDVSGFEREDPARDYFIIREEMKKYSPFLLEKPEIVVANKIDLLEREKLPQRIKEIESSIGKEVIPISAVTGEGVDLLLDRVASIVRKERIEREERKEKKDHPMEKPAPVWRKLPERFEVEVVKEEDGQWVVEGEGLRVWMERFDLNQRDARLLILQILEKNGLEEKLKEAGVKEGDVVRIGNFEFEYRE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCL1_ASPNC
Sequence: MPSAHAFDMRITSDIYKPDQHLPMETMKVCAVTMTEDLQEDDGSSDESDNDEREDHSKTGVSQQRITQNAKFKALLAQRADTGPIHDVSVTHDLPDAQLSTAHLVAKQDLGIGTLDPREYQLELFERAKVQNTIAVLDTGSGKTLIAVLLLKHTLEKELNDRMEGKPHRIAFFLVDSVTLAYQQAAVLRNNLDQSVGHFFGAMGTDLWSKSVWDQHFQKNMVIVCTAEILNQCLLNSYIKMSQINILIFDEAHHTKKDHPYARIIRDSYLEEVYSKRPRIFGMTASPIDTKGDIVDEATRLEKLLDSRIATTSNMSLLRQVARRPVERVWSFNKLEQPFATSLYKHLEDRFGDMACLEGIFRFAWQASSELGRWCSDRAWARALADDVLPKLEGSVRKTANSETSSNVPESAYKEILRITEASEIVKSYAFSSPETFGQLSPKVQVLREELARYFGRQTETKCIVFTQKRYTALILAELFQTLNIPFLRPGVLIGVRSGDLAGMNITFRQQFISLVKFRTGEINCLFATSVAEEGLDIPDCNLVVRFDLYQTLIQYVQSRGRARHFNSTYASMVERGNLEHEQRLLEVQDAEMMQSFCRTLPEDRLLYGFDHDLDTVLQKDEGNRTFRIKSTGAKLTYHSATAILARYASSLQYEKEFSAQVTYVVLPINGAFVCEVILPEKSPIRGLTGSPAMKKSIAKRSAAFDTCLLLRKNKLLDDHFNSIYHRRLPAMRNAKLAITSKRTSQYDMISKPSLWGRKQGMPPKELHGTFITFLPSMQLSHEPAPLLLFTRERLPHFPEFPIFLDDDVETTIITTPLEKQLLLSEKEVDALTVFTLRVFRDVFHKTYDKEPEKMAYWLAPAKVQSSYLPSYDPRQILDWESLTYVRDNDSIPFSTNADPESWVDLFVFDAWDGRCRFFTVGVEHSLTPSSPPPPFVARRRHMNDVMNYCLSLSKNSRAKFLSTCHWDQPVLRAELVRLRRNLLDKMTDTERDVETRCFICIEPLKVSAIPASTAFSCLAFPAIISRIDAYLISLQGCESLNFTVKLDLALEAFTKDSDNTDEHRAQQIHVQRGMGRNYERLEFLGDCFLKMATSIALFTQNPDDDEFDYHVNRMCLICNKNLFNAAVDKEIYKYIRSRGFSRHTWYPEGLKLLQGKDHSRKATTESKHALAEKTIADVCEALIGAALLSGGPDHRFDMAVKAVTTLVNSPSHKAERWKDYISFYTIPKYQRRAADGAELYLSRKIEEKLSYRFRYPTLLGSAFTHPSYPSAWAKVPCYQRLEFLGDSLIDMVCVEDLFARFPDRDPQWLTEHKMAMVSNKFLGALAVKLGLHTHLKYFSAPLQSQITQYAEEIQTAEGESEGAVDYWTVTKDPPKCLPDMVEAYVGAVFVDSDFNFEVIERFFRDYIKPFFEDMAIYDTFANKHPTTFLHNRLTNEFGCVNYCLKAGEMPSIDGAPAGVLAAVIVHDVVIAEGTATSGRYAKVKASEKALAVLDEISSAEFQRKFRCDCRESGDSARLDIGTAI
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: PDXB_ECO45
Sequence: MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLSEGQKLSVVLDVWEGEPELNVELLKKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.