PharMolix/UniProtQA huggingface dataset:
Protein: GPMI2_METAC
Sequence: MWNSLHMTQARRPLMLMILDGWGYREASEGNAILAAETPNLNSLLNEFPWCFLECSGEAVGLPEGQMGNSEVGHLNIGAGRVVYQDLTRINLSVRNGDFFENPVLLDAISNVKLNDSSLHLMGLVSYGGVHSYMTHLYALIKLARDKGLKKVYIHAFLDGRDVPPKAALADIRELDAFCKENGSARIATVQGRYYAMDRDKRWERSKLAYDALTLGVAPYTTSDAETAVSDAYARGETDEFVKPTVVTGSDGKPEAVVQDNDSIIFFNFRPDRARQLTWAFENDDFDGFPREKRPKVHYVCMAQYDETLDLPIAFPPEELENVLGEVLSKQGLVQLRIAETEKYAHVTFFLNGGQEKCYDGEDRCLIPSPKVATYDLKPEMSAYEVTDEVIRRIQSGKYDVIVLNFANMDMVGHTGIFEAAVQAVEAVDTCVGRIIEALKKAGGVALITADHGNAEQMENQHTGEPHTAHTSNPVRCIYAGKGEVKALENGKLSDLAPTLLDLLGVPKPEEMKGKSLILNE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2, BPG-independent PGAM 2, Phosphoglyceromutase 2, iPGM 2.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RPOZ_SYNSC
Sequence: MLSAGVDSKDLSKRGESLIRQSSNRYLTTVRIAFRAKQRRFDDFDGLLEESSVKPVQRAIVELSDEQDQPDLLPG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: NADK_ECO8A
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_PSEE4
Sequence: MIKDPFERLGLDREVLTVSQLNGRARVLLEDVFRSVWVEGEISNLARPASGHMYFTLKDSGAQIRCALFRQNALRVRQALRDGLAVRVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFEALKEKLGAEGLFSTERKRPLPAHPQRIGIITSPTGAVIRDIISVFRRRAPQVELNLIPTAVQGREAINQIVRALQMADRQGFDALILARGGGSLEDLWCFNEEAVARAVAACVTPIVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDSSGLQQRLDSLQRRLLLRMQSRLAHDRLRVEGLARRLRHPGERLRQQAQRLDDLDMRLRRAFALNMNQRHERLGRLDTRLAAQHPGRSLKLLKQRLDSLAERLPKAMRDVLKDRRQRFQAQLQTLQVVSPLATLARGYSILLDEHGQAIRSAAQTHNGQRLTARLNEGELKVRVEDNHQTPVTLSLLD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_PHOPR
Sequence: MLSVEELSCVRDERVLFDNLSFTISSGELIQIEGHNGAGKTTLLRIIAGLGRADSGQVCWKSEGIESAREDYYQDLLFLGHQTGVKRELTAYENLAFFQAMHNESIDQDMSGKPPVLGDESLWQALAQVGLAGREDVLAGQLSAGQQRRVALARLWISNHKLWILDEPLTAIDKQGVKVLESLFLSHVERGGIVLLTTHQDMFADSNHLRKIKLGQ
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HUTI_SALSV
Sequence: MRQLLPGDTVWRNIRLATMDPQRQAPYGLVDNQALIVRGGHICDIVPETQLPVSGDNIHDMQGRLVTPGLIDCHTHLVFAGNRAAEWEQRLNGASYQHISAQGGGINATVSATRACAEETLYLLARERMMRLASEGVTLLEIKSGYGLELATEEKLLRVAAKLAAENAIDISPTLLAAHATPAEYRDDPDGYITLVCETMIPQLWQKGLFDAVDLFCESVGFNVAQSERVLQTAKALGIPVKGHVEQLSLLGGAQLVSRYQGLSADHIEYLDEAGVAAMRDGGTVGVLLPGAFYFLRETQRPPVELLRRYQVPVAVASDFNPGTSPFCSLHLAMNMACVQFGLTPEEAWAGVTRHAARALGRQATHGQIRAGYRADFVVWDAEQPVEIVYEPGRNPLYQRVYRGKIS
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BRUC2
Sequence: MGQKINPIGLRLGINRTWDSRWYANTGEYGKLLHEDVKIREFLTEELKQAAISKIVIERPHKKCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTNADTSLNIVEVRKPEVDATLIAQLIAQQLERRVAFRRAMKRAVQSAMRLGAEGIRINCSGRLGGAEIARMEWYREGRVPLHTLRADIDYGTAEAKTAYGICGVKVWVFKGEILEHDPMASERRAVEGDNQGSSSNRRRENA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y1096_SULNB
Sequence: MTLFIDGDAFPNLLKPIVLRSIERLALPTKVIANKKINIGRSSHIEYIIVDQGADEADHRIVDLCQKDDLVITADIPLADRIISKEGHAIDHRGELYSIENIKQYLAMRNLMESIRESGEMTGGPKAFGPKDAHAFANQFNAFLAKNC
What are the official names of this protein?
UPF0178 protein SUN_1096.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: FB99_ARATH
Sequence: MIETNKKASWSELCPDVLRCVFELLSFSDLNRTRSVCSSWHSASRHCVPTQNQIPWLILFPRNNVNNNNNNSCVLFVPDDRDSLYKTKDLGVGFMLSNCLATYGSWILMMDRLCNLNILNPLTGEKIDLPRTKFDLPRLESSVACLWIDEKTKDYIVVWKIKNSLVYAKKGNHTWQQVFSMNEELSVEQIVYEHKTQKLYVHFNDSTLSIWRLSREDPHGVFENYIPFDFVFQDFLPDRRTDEELYVKEYIDTRLNIALTTSGELLKVASVVQKSKRWLFRIYKMNYIKRRWERIESLGDEALILDMGITIVAKDIPGLKRNSIYISGFDYGRKHLDHIFIFDLTTQESEPLPYCVSSSNDFSDARWFFPSFSQSPY
What are the official names of this protein?
F-box protein At2g05970.
Protein: POTA_STRPB
Sequence: MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGSGKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAFALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVLLDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQSGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEVVIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIGLDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RLUE_VIBCH
Sequence: MSSRLSSDATSSSSDQRKSHFKQRAAKNAGHPPTRANRKSVANKKKNATQTALSPKRPLSPAERKVILFNKPYDTLSQFTDGDGRKTLADYIPIKDVYAAGRLDRDSEGLLILTNDGILQARLTQPQSKAPKTYWVQVEGSPQESDLEALRHGVTLKDGPTLPAKVDIMPEPTLWPRNPPVRFRAAIPTTWLAITLMEGRNRQVRRMTAHIGFPTLRLIRYSMGDWNLGDLQPGEWREVTL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase E, rRNA pseudouridylate synthase E, rRNA-uridine isomerase E.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: TIG_SHEB2
Sequence: MQVSVEATQGLERRLTISVPAEQIEKLVKDSLQREAKRARIPGFRPGKVPITVINKRYGAAIRQDIMGEVMQRNFIEAIIAEKLNPAGAPTFVPGSTDGEKFEFIATFEIYPEVELKGLDAIEVEQPKAEVTDADVDTMIETLRKQHATFAAVEREAADGDKVKMNFVGSVDGEEFEGGKADDFELQLGSGRMIPGFEAGILGHKAGEEFVIDVNFPEEYHAENLKGKAAKFAITLTEVQAANLPEVNDEFAALFGISEGGLEALKAEIRKNMNRELEQALKANVKEQVINGLLANNDITLPKALIDGEVNVLRQQAMQRFGNQTANMPELPAELFTEQAARRVKIGLLLGEVIKTNELKAEDERVQGLIASMASAYEDPSEVVAYYNSNKELMQNMRNVALEEQAVEALLKSAKVTEKEVAFEEFMNKATGRA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ASPD_BURM7
Sequence: MRNAHAPVDVAMIGFGAIGAAVYRAVEHDAALRVAHVIVPEHQCDAVRGALGERVDVVSSVDALACRPQFALECAGHGALVDHVVPLLKAGTDCAVASIGALSDLALLDALSNAADAGGATLTLLSGAIGGIDALAAARQGGLDEVRYIGRKPPLGWLGTPAEAICDLRAMAAEQTIFEGSARDAAQLYPRNANVAATVALAGVGLDATRVCLIADPAVTRNVHRIVARGAFGEMSIEMSGKPLPDNPKTSALTAFSAIRALRNRASHCVI
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: USPA_ECO57
Sequence: MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKYDMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein A.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ACIBS
Sequence: MQVTTEAVSGVARRLNVSVPTSRINEQFEARLKRTAKTVKINGFRPGKVPANVVRREYGASIYQEVVNDIIRDSVFEAIQQEKINAVGTPNIEKVEHKEDALVFEATVEVYPEVEVKAFDGLEVERKTAEIKDADVDTMIENLQKQRQTWAVTKGMAKKDMQVTFDFEGSIDGEKFEGGSAEDFKLVLGSGRMIPGFEDGIIGMKAGEEKVIDVTFPEDYQAENLAGKAAQFKITVKQVEKPKLPEIDAEFLKIFGVSEEEGIEKLKADVRKNMEREVRNGLRNQVKQAAFDALVAANEIEVPAAMVAQEIDRQRQQMVQQFTQQFGGAGAQSFDKSMLPDELFKEQAERSVKLGVLVSKVLADAKLEVDQARVDAYIDDMASSYEDPTEVIEYFKNDAQQRAQIEAVVLEDQVVDHILASAKVTDKAVSYEDLLKEQQARRMG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: 6PGL_SERP5
Sequence: MKQIVYVASPESQQIHVWQLSDAGALELLQTVEAPGQVQPMAIHPDRTHLYVGVRPAFGIVSYRIEADGTLQQAGMAPLPGSPTHISTDLQGRYLFSASYSGNCASVSPIGHDGVVVAPIQQIDGLTAPHSANIDPTNQLLLVPCLKEDRIRLFNLDLQGELTPHTQEAVTTASGAGPRHMAFHHNDKYAYCVNELDGTVDVFAISENGGKYTLVQTLDIMPADFNGTRWAADIHITPNGRFLYTSDRTASILTIFSVSEDGSTLSVVGYHPTEEQPRGFNIDHSGRFVISSGQKSGHIGVYEIDQASGKLTTLARYPVGKGPMWVSILAK
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: Y1347_PROMT
Sequence: MAGFGLPNFGQLTEAFKKAQQIQQNAQKLQEELEVMEIEGTNDDNRAKIWMSGNQKPLRVEIDPSLLSEGKAIIEEAILDAMKSAHEVSTSTMKERMEDLTGGFKLNLPGMGEEN
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PMN2A_1347.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YFKQ_BACSU
Sequence: MNKRDKALQLIKELEDNQDRPISPNLKENLENLTLLTEGCSDIVFRQFDFGNGLCGFIVYIEGIVKSEHIQDHALRPFLMHLTDQIDEHEEALQNTLSISSVALETSMSKVAASIIEGNAVLFADGHSKGLILNIKGGQRRSIEEPITESTIRGSREGFTESLRVNTALVRFRVKTFQLKMISFKIGTKTKTDVVLAYIDGLADPKVIDKAKKRIKKIKIDAVLESGYIEEFIEDDTYSPFPQLQYTERPDTVAAQLLEGRFAIFTDNTPFVLTGPITFWQLMQASEDYYERYLMSNLIRWLRYMFLFVALYLPAIYVAVITYHQDLMPTNLMFSVASAREPIPFPAIIEALIMEISFEALREAGVRLPKTIGQTVSILGALVIGTAAVEAGIVSAPMVIIVSLTGIASFTIPRFNLAISIRMLRFPLMFLASIFGIFGIMLGTIILVLHLCKLQSFGIPYLSGISPFKRDEVKDIFVRAPWWTMTRRPGTYSRGNGQKGAKREDPKDEENNI
What are the official names of this protein?
Uncharacterized membrane protein YfkQ.
What is the protein family that this protein belongs to?
Belongs to the GerABKA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIA_HAHCH
Sequence: MKSQGRPLPSVAEQFKARLPVYIGLTRLNRPIGTYLLLWPTLWALWLASEGAPSLKNLFIFVFGVLLMRSAGCVINDYADRRIDMHVERTKGRPFAQNQVTEKEALTLFGILVGVSFILVLFTNALTIYLSAGALALASTYPFMKRHTYLPQVVLGAAFAWGIPMAFAAELDAVPQQAWLLYTATVVWTVAYDTMYAMADREDDLKIGVKSTAILFGEADRAAVAGLQVLTLGVLFMVGAQHELGVYYQVSLIIVAVLFVYQQHLIRDRSSQHCFKAFLNNHWVGAAVFLGLVLEFLFRP
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPP2_THEVB
Sequence: MPIGVPKVPYRLPGEPYTQWIDIYNRLYRERIIFLGKEVDDEIANQIVAVMLYLDSEDPGKDIMLYINSPGGSVTAGMAIYDTMQHIKSDVVTICVGLAASMGSFLLAAGTKGKRLALPHSRIMIHQPSGGTRGQATDIEIEAREILRVRRQLNELYAYHTGQPLEKIERDMDRDFFMSAEEAKNYGLIDRVIEERSN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBID_BURP1
Sequence: MKYKDLRDFIHGLEQRGELRRVTQPVSPVLEMTELCDRVLRAGGPALLFDAPAGHRFPVLGNLFGTPRRVALGMGVDADDEAALASLRDIGRLLSALKEPDPPKRLKDAGKLLSLAKAVWDMSPKTVSAPPCQEIVWEGDDVDLHKLPIQTCWPGDAGPLLTWGLTVTRGPNKTRQNLGIYRQQLIGRNKLIMRWLAHRGGALDFREFALKHPGQPYPVAVVLGADPATMLGAVTPVPDSLSEYQFAGLLRGARTELAKCVTPGVDALQVPARAEIVLEGFIHPQQGAPAPAPEGAPPRPAAGAAAGYEHALEGPYGDHTGYYNEQEWFPVFTVERITMRRDAIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFAEITDFYLPPEGCSYRMAIVQMKKSYAGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVNVRDWKEVIWAITTRVDPARDTVLVENTPIDYLDFASPVAGLGSKMGLDATNKWPGETQREWGRPIEMDAAVKARVDRLWTEIGLS
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: INVO_TUPGL
Sequence: MSQQHTLPVTLPAALSQEPLKTVSPPPNTQQEHTKQPTPLPAPCQEVPSELPVEDPSKHKEKHTTPVKGVPEQEHELQQQQDSQEQELHLGQQQQQQEYQEQELHLGQQQQQQEYQEQELHLGQQQQQEYQEQELHLGQHQQQTSQEQKLHLGQQQQHQESQEQKLHLEQQQQEPQKQELHLGQQEAQEEELHLKQQQQECQKEEVHLEQQQQECQKEEVHLEQQQQECQKEEVHLEQQQQECQKEEVHLEQQQQECQKEEVHLEQQQQECQKEEVHLEQQQQETQELQQHQGAGILEQKLHQEKAQSEQQLKGQLDWEEKLLDQQLEQELAKRDEQLGKKEEQLLEPSEQQEGLLEQPTLVPAPSQLHENQAAQVPKGEVLLPIEQQRQQEVQWPVKHK
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Involucrin.
What is the protein family that this protein belongs to?
Belongs to the involucrin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: YR739_MIMIV
Sequence: METNFYKFFKKSLFTDLHLTISDSEDSIEMNVHRIILCAKSSYFNTLLTGEFRENNSKDLKIIVQDRIIARDIILNMYGRLLYNDDYPDWYYNLLLIQCKDFFGMTINPESIYKLKVPSEAYDLLVQVVNMFKINSDLVSLLVDNLPSEYDLSKIPINVFQLMCQHTKRDYVIFPDSKKIGIVELFGSDFTNKRNYIQTKKSPENITVSSNQIAVSTYSGSIHIYSLMTLEKIHKIKTSCVKLSYTSDGSYLLAVVRESEISVCIIVYCSKTFQIVSKINIDDFVNVFCCTSDNKYILVANKTKIDVWDLQTGQFIKTMGICKNKINCIDCSSNNKYIASGDDDGQTIVWDFETGNIVKTFISMSEIYAVKFTLDNKRIAYGGRNRKLKLDYFGNTDTLSNKDYILTTLSHQYYEYIYDIKFTSCDKYIVFSGRDNDIVCVEVGTVNSCHRLDTKNVTIKNIGVFSDYNNETIRNYIHQMKNKNSEKIDI
What are the official names of this protein?
Putative BTB/POZ domain and WD-repeat protein R739.
What is the protein family that this protein belongs to?
Belongs to the mimivirus BTB/WD family.
Protein: DNAA_TERTT
Sequence: MSDPCWEQCVSCLQNELPSQQFNTWIRPLRVEESSTLLLRLIAPNRFVQDWVNDKYRTRIEEIISNSDAGPKSLEIAVAQRARAGFEVVRNAKVAPAVPVPDPLPSTGRDESSFQPPKGNTSADYSGHSDLGFQSPHRRQSPFSESQERFTQPLEMSRFGSGRPSNERSNEGAIGGSTESSADRERIPLQGVVEDLFKPTKNSNDFVEPRSTDPLLEIESRPIIETVSPRDIQDFGSQLTSRVKKKDVEGGIQHKHNLNTTFIFDNFVVGKSNQLGLAAASQVAENPGGAYNPLFIYGGVGLGKTHLMHAVGNALVQRKPGARVVYLHSERFVADMVKALQLNAISDFKRFYRSVDALLIDDIQFFAGKERSQEEFFHTFNALLEGGQQIILTCDKYPKEINGLEERLKSRFGWGLTVAIEPPELETRVAILKRKAESSRMPLPDDAAFFIAQRIRSNVRELEGALKRVIANAQFTQRSISVELVREALKDLLALQDRLVSIDNIQRVVAEYYKIKVSDLHSKRRSRSVARPRQVAMYLAKDLTHHSLPEIGDAFGGRDHTTVLHACRKIRDLQESDADIREDVKNLLRTLTT
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_CAMJ8
Sequence: MKTFLVCALEPSANLHLKEVLKAYKKDFGEFELHGIYDESLCKEFDLNSKPLYSSHEFSAMGFIEVLPLIFKAKKAIKELVNLTLSQTMDAVLCIDSPAFNIPFAKALKKAGSKIPRIYYILPQVWAWKKGRIPIIESHFDILASILPFDNQFFNKSTYIGHPLLDEIKEFKNQEDINHTFSKKDDEKTIAFLPGSRRSEIRRLMPIFKELSQKFKGEKILCVPSFNLEKLEVYGDISEFKIESNTPKVLKKADFAFICSGTATLEAALVGTPFVLAYKAKAIDIFIAKLFVKLKHIGLANIFCDFAGKEALNPEFLQDKVNVLNLYEAYNKYDYKAFFAKVDFLKEYLQFGSAKNLAKILNEI
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: TPPP3_HUMAN
Sequence: MAASTDMAGLEESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALEELATKRFKGKSKEEAFDAICQLVAGKEPANVGVTKAKTGGAVDRLTDTSRYTGSHKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGTYDAKVKK
What is the function of this protein?
Regulator of microtubule dynamic that has microtubule bundling activity (PubMed:17105200, PubMed:19633818).  Required for embryo implantation; possibly by regulating beta-catenin (By similarity).  Also required for decidualization via regulation of beta-catenin (PubMed:30667362).
What are the official names of this protein?
Tubulin polymerization-promoting protein family member 3, TPPP/p20.
What is the protein family that this protein belongs to?
Belongs to the TPPP family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: RECR_BRUSU
Sequence: MSKRIAGPEIERLIQLLARVPGLGPRSARRAALHLIKKKEALLVPLGGAMQEAAEKVRICSCCGNVDTSDPCTICTDERRDPATLIVVEDVSDLWALERAGTMNVRYHVLGGRLSPLDGIGPDDLNIKGLVERVASGAIKEVILAVNATVEGQTTAHYITDQLSNFDVRVTRLAHGVPVGGELDYLDEGTLAAALRARTTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PTH_LEGPL
Sequence: MAIKLIVGLRNPGSAYEQTRHNAGAWLVTALAQRHNSHFKIDKKMQAELTEIDINNHPCRLLLPLTFMNHSGQTTRIISQFYKIEPGEILIVHDELDLPVGRIKLKTGGGHGGHNGLRDITAQLGTGEFHRLRIGIGHPGHKDLVHQYVLSRPSMHDRQQIYDAIDRGIAIIPIVLSGDIARAMNQVNA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPL1_MICPC
Sequence: MSGGDIDPTAINSPKFRLIAVQCLFALTAFATMAGQNKNLAGPDAMTLEECGPYGCGYHKFAVFQFLVVICVTYWLFTMLWMGMYLIQKVPPAGTEFMIYAVFNVLILIAFSTSWTECNETIVDPTYPVCKRATGAKASIAFAMFTWLALCVSMMFTWKEWRDQNYEGLPIFGDFSSFMPGGGGGGMGGGGGYERPSDVNTQTYA
What are the official names of this protein?
CASP-like protein 0U1, MpCASPL0U1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAD_ERWT9
Sequence: MSTKAIYPGTFDPMTNGHLDIVTRAALMFDRIVLAVAASPSKKPMFSLEERVALAKEVVAHLPNVDVVGFSDLLANFAKAQQANVLVRGLRAVSDFEFEMQLAQMNRHLMDTLDSVFLMPSEQYSFISSSLMKEVARHGGDVETFLPAPVYKALKARL
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_AZOSB
Sequence: MSTLPIRTVFFISDGTGITAETLGHSLLAQFPEARIRQVRAPFIDDLDKAIDCANQIREAARNDGVRPIVFSTLVSPETVEALHKADALFLDLFDRFIGPLETELGQRSTHTVGRFHGIADSLDYKNRIEAINFAMAHDDGVSSDGELAEADVILVGVSRSGKTPTSLYLAMQFGVKAANYPLIPEDFERNKLPGELHNYRGKLFGLTIAPERLSQIRQERRPNSRYASLDNCKYEIDAAQKLMRRENIRWLDSTTKSIEEISATILQSVRLNRPGY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.