PharMolix/UniProtQA huggingface dataset:
Protein: ADEC_METB6
Sequence: MDAPPLHANLIPAARGTEPADLVLKNAMLFDAFSCSWEEGDLAIKDGIIVGTGRSYRGIRERDLGGALVVPGLIDAHVHIESSLLVPQEYAHLVAAHGTTTVIADPHEIANIAGKEGIEYMLACRAGLPVDILYMLPSCVPATPADVGGAVLDAGDLAGFPGRDGILGLGEMMNVPGVLGGDPGVLAKLVLSRIRDGHAPHLSGPDLNAYLLSGPDSDHECTTASEAKEKLRCGMYLFVREGSTEKNIAALVPVVTPYTVSRCSFCTDDCHADLLAHSGHIDRCIRTAVAGGLEPELALRMATLSPAERFSLPDRGALAPGRRADFCIVDDPRHFAVKETYSRGRPVAEYAAPQARPPVFAALRCTVPSRDQIRLFGTGRARVIGLVPGQILTESLTFDLDAAALPDISRDLLKLVVCNRYGKGSVGTGIVHGFGFKDGAIAASISHDAHNIVAAGTGDEVILSALTAVIRAGGGMAAVHKKDVTVLPLDCAGLMSTHPAREVIAGLDALSAATRRIGGIDDPFMYLSFLALTVIPALRLTDRGLFDAVAFRDVPVFP
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: NEP_I71A2
Sequence: MDSNTITSFQDILQRMSKMQLESSSVDLNGMITQFERLKIYRDSLGESVMRMGDLHSLQSRNATWREELSQKFEEIRWLIAECRNILTKTENSFEQITFLQALQLLLEVESEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: AIM18_YEAS8
Sequence: MDRGRCANMLKSLQRTLAKCQKSPSTNHWQCFKRNFTSIRATKYPGRSNSTFHYWPWFAASTLLATSLYYRDRPVQNDDKTDAFPSHTESIQVDSSVSDFPLTITALNFPVSTTFKLLGYGQRHVTFLRFKVYALGLYLAENDENLVSDTLNETYLHKYFLDVDDSKTPKENLARLLKRDDSKSVMMIDDLLDSGMRMLAKITPVRNTDFKHLKEGLVKTISKHPDVANNKDTLAKGLSELNDAFSRKGSVRKNDDLIIELLANGALQFSYHDSKNNEFEVMGVVNNQLVGKFLFSQYLCGEKSPSPQAKKTAIDKLITLL
What are the official names of this protein?
Altered inheritance of mitochondria protein 18, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM18/AIM46 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYN_STAAM
Sequence: MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEIAQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQYVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRAM_I66A1
Sequence: MNPNQKIITIGSVSLTIATVCFLMQIAILATTVTLHFKQNECNPPANNQVVPCEPIIIERNITEIVYLNNITIEKEVCPEVAEYRNWSKPQCQITGFAPFSKDNSVRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNGTIHDRIPHRTLLMNELGVPFHLGTKQVCIAWSSSSCHDGKAWLHVCVTGDDRNATASFIYDGMLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGNADTRVLFIREGKIIHISPLSGSAQHIEECSCYPRYPDVRCVCRDNWKGSNRPVIDIKMADYSINSGYVCSGLVGDTPRSDDSSSNSNCRDPNNERGNPGVKGWAFDNGDDVWMGRTISKDSRSGYETFRVIGGWTTPNSKSQVNRQVIVDSNNWSGYSGIFSVEGKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: CL4B1_GLORO
Sequence: MATNTMLCLLILSVVLALAFATNKKGDEEPENHSTGIFGKVGRVVTVALAMSSRLGGADATRGGGAVYGGNLKSNLLPNNNWMAPPPPMAMRSAKVYDSKHSPAEYLKKFAQDFRRKTGMHSQRHHEETTLEQEKRVAGAGPDPIHHQDTTLEQEKRAVPAGPDPKHHEETTLEQEKRAVPAGPDPKHHEETTLEQEKRAVPAGPDPKHHEETTFEQEKRGAPAGPDPIHH
What is the function of this protein?
Mimics host plant CLE extracellular signal peptides that regulate cell fate.  May play a role in the differentiation or division of feeding cells (syncytia) induced in plant roots during infection.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 4B-1.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host extracellular space. Secreted, extracellular space, apoplast. Note=Present in secretory granules within the dorsal esophageal gland secretory cell and in the dorsal gland ampulla (collecting reservoir) at the base of the nematode stylet. Secreted into host root cells via the nematode stylet to transform the recipient cells into enlarged multinucleate feeding cells called giant-cells or syncytia. Secreted to the host apoplasm from its cytoplasm via a plant secretory pathway (By similarity).
Protein: ODPB1_ORYSJ
Sequence: MLGIARRRLGSGCALGQLMQALRPAAAAAAARTYSAAAKEMTVREALNSALDEEMSADPSVFLMGEEVGEYQGAYKISKGLLDKYGPDRVLDTPITEAGFTGIGVGAAYQGLRPVVEFMTFNFSMQAIDHIINSAAKSNYMSAGQINVPIVFRGPNGAAAGVGAQHSQCYAAWYAHVPGLKVLTPYSAEDARGLLKAAIRDPDPVVFLENELLYGESFPVSAEVLDSSFCLPIGKAKIEQEGKDVTITAFSKMVGYALQAAEILSKEGISAEVINLRSIRPLDRATINASVRKTNRLVTLEEGFPQHGVGAEICMSVVEDSFEYLDAPVERIAGADVPMPYAANLERMAVPQVEDIVRAAKRACYRAVPMAATA
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial, PDHE1-B.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PME58_ARATH
Sequence: MGVDGELKKKKCIIAGVITALLVLMVVAVGITTSRNTSHSEKIVPVQIKTATTAVEAVCAPTDYKETCVNSLMKASPDSTQPLDLIKLGFNVTIRSIEDSIKKASVELTAKAANDKDTKGALELCEKLMNDATDDLKKCLDNFDGFSIPQIEDFVEDLRVWLSGSIAYQQTCMDTFEETNSKLSQDMQKIFKTSRELTSNGLAMITNISNLLGEFNVTGVTGDLGKYARKLLSAEDGIPSWVGPNTRRLMATKGGVKANVVVAHDGSGQYKTINEALNAVPKANQKPFVIYIKQGVYNEKVDVTKKMTHVTFIGDGPTKTKITGSLNYYIGKVKTYLTATVAINGDNFTAKNIGFENTAGPEGHQAVALRVSADLAVFYNCQIDGYQDTLYVHSHRQFFRDCTVSGTVDFIFGDGIVVLQNCNIVVRKPMKSQSCMITAQGRSDKRESTGLVLQNCHITGEPAYIPVKSINKAYLGRPWKEFSRTIIMGTTIDDVIDPAGWLPWNGDFALNTLYYAEYENNGPGSNQAQRVKWPGIKKLSPKQALRFTPARFLRGNLWIPPNRVPYMGNFQ
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor 58.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RUBR1_ALCBS
Sequence: MKKWECVVCGFIYDEAEGLPDEGIEPGTAWNNVPEDWVCPDCGVGKDDFEMVEI
What is the function of this protein?
Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
What are the official names of this protein?
Rubredoxin-1, Rdxs.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KI2L3_HUMAN
Sequence: MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP
What is the function of this protein?
Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7).  Inhibits the activity of NK cells thus preventing cell lysis.
What are the official names of this protein?
Killer cell immunoglobulin-like receptor 2DL3, CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, NKAT2a, NKAT2b, Natural killer-associated transcript 2, NKAT-2, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I-specific NK receptor.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL3_STRZP
Sequence: MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETDGYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAGRMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SEBP2_RAT
Sequence: MASERPREPEGEDSIKLSADVKPFVPKFAGLNVAWSESSEACVFPGCAATYYPFVQESPAAEQKMYPEDMAFGAPAFPAQYVSSEIALHPFAYPTYALESTQSVCSVPTLQYDYSQAQCHPGFRPAKPRNEHACPPQEAKCVFKKKSSDERRAWEEQKSSNRRADGAVPCEARPARGSCHLKSDGYHKRPDRKSRILTKSASTSKPEFEFSRLDFPELQSPKNSNLPETQKQPRWGPLGPAASNMSLLGEAGKPVADMVEGKMVKTDHTDGAVTNNAATSSPSCTRELSWTPMGYIVRQTVSSDSAAATETVNSIINLKKTTSSADAKNVSVTSEALSSDPSFSREKRVHPGPKAKASQGSELEQNESSKKNKKKKEKSKSSYEVLPVQEPPRIEDAEEFPNLSVASERRHRGESPKLQSKQQAQNDFKTGGKKSQVPVQLDLGGMLAALEKQQHAPHAKPSSRPVVFSVGAVPVLSKDASSGERGRRSSQVKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERMQQRLQESAVSPTVASDDSQDVESGVTNQIPSPDNPTGPEKTEEPMSSTPVVEGESEEPAGTEFQRDPEACQPAPDSATFPKIHSRRFRDYCSQMLSKEVDACVTGLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKTQSKGGLDDTLHTIIDCACEQNIPFVFALNRKALGRSLNKAVPVSIVGIFSYDGAQDQFHKMVELTMAARQAYKTMLETMRQEQAGEPGPQTPPSPPMQDPIQSTDEGTLASTGEEPHYIEIWRKHLEAYSQHALELEDSLEASTSQMMNLNL
What is the function of this protein?
Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins.  Binding is stimulated by SELB.
What are the official names of this protein?
Selenocysteine insertion sequence-binding protein 2, SECIS-binding protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNC1_ARATH
Sequence: MELCSSSPSSSLLRICSSSAPEISFSSSISQFPSKTQSILTKSRFQNLRICASVTAETQGLPRDSPQRLLKELAQRKTATGPKKKVPPKRFILRPPLDDKKLAERFLNSPQLSLKSFPLLSSCLPSSKLNNADKTWIDEYLLEVKQALGYSLEPSESLGDDNPAKHFDTLLYLAFQHPSCDRARARHVKNGHSRLWFLGQYVLELALTEFFLQRYPRESPGPMRERVFALIGKRYLPKWIKAASLQNLIFPYDDMDKLIRKEREPPVKSVFWALFGAIYLCFGMPEVYRVLFEVFGMDPDADECQPRSRRQLEDVDYVSVEFEGKKLGWQDIATYKPPEDALFAHPRLFRACVPPGMHRFRGNIWDFDSKPKVMQTLGYPLTMNDRIKEITEARNIELGLGLQLCFLHPSKHKFEHPRFCFERLEYVGQKIQDIAMAERLLMKHLDAPGKWLQEKHRRLLMNKFCGRYLREKRLHNFIIYSEEVHDRYEHNRRLRNPATTAVQQAIHGLAYTIYGKPDVRRLMFEVFDFEQIQPKAV
What is the function of this protein?
Binds specific group II introns in chloroplasts and facilitates their splicing.  Acts on both subgroup IIA and subgroup IIB introns.  The substrates of the subgroup II also require the CRM domain proteins CAF1 or CAF2.  Binds both single-stranded and double-stranded RNA non-specifically, but lacks endonuclease activity.  Required for plastid ribosome biogenesis.
What are the official names of this protein?
Ribonuclease III domain-containing protein RNC1, chloroplastic, Chloroplast ribonuclease III domain protein.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CEP55_DANRE
Sequence: MAAKGAKETLVNKLGFKSSSSSSKSAELEVEKLKRENQQMKKSLEDMKRAGRHQHTHPDTDKARLLERILALETLREKNNQQLLGREQEITTLRQQLRSAHGEVVSSLQSQLENKQHEAEQRERQYQALVKETEDLKNKYCAVSERCDTLEKQKGSSGELAVVQEQLRDALEKNQHWLVYDQQREAYVQGVLARIKDLEAQLNEANQALQQQHKEAKSDDQSAQKVQQELEAERNKVSRMQMEVEDLQVRYEEKSREAAQAREQLLEERRREREDRKSSVERDALLQDQHRKREAELIMQVNLLQKSLMNQKEEQKRMAILEQQIQLSAKESENEKLDRQTLQHQLHKVLKELRKARDQITRLESSKQQRESRFSEPSSYNRMDLERLTIQDHMTSPSKVHNILDESVLECPNCGASYPTSQHRELLAHLDYCFT
What is the function of this protein?
Plays a role in mitotic exit and cytokinesis.  Recruits PDCD6IP and TSG101 to midbody during cytokinesis.  Required for successful completion of cytokinesis.  Not required for microtubule nucleation (By similarity).  Plays a role in the development of the brain and kidney (PubMed:28264986).
What are the official names of this protein?
Centrosomal protein of 55 kDa, Centrosomal protein 55-like.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody, Midbody ring.
Protein: LEUD_HELMI
Sequence: MEFTGRVWKFGKDIDTDAIIPARYLNTTSPEELAKHCMEDADPSFPQKVRKGDIIVADKNFGCGSSREHAPIAIKAAGVPCVIAKSFARIFFRNAINIGLPIFECPEAVDGIREGDVVQVNADRGVIFNMTTGQTYTAKALPASMQSIIQAGGLMQYVKTRVAEGK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: Y2080_YERPE
Sequence: MLCAIYRSPKRDQTYLYIEKKDDFSRVPAELLASFGKPQFAMLLALNERKTLATADVEKVKNALIEQGFYLQVPPPPESLLKMHLGETKA
What are the official names of this protein?
YcgL domain-containing protein YPO2080/y2231/YP_1923.
Protein: RIMO_ACTSZ
Sequence: MTHSVPNIGFVSLGCPKNLVDSERILTELRSDGYNIIPTYENADLVIVNTCGFIDSAVQESLEAIGEALEANGKVLVTGCLGAKEDRIREVHPKVLEITGPHSYEAVMEHVHKYVPKPAYNPYINVVPSQGVKLTPKHYAYLKISEGCDHKCTFCIIPSLRGDLDSRPITQILDEAKRLADSGVKELLVVSQDTSAYSLDQSKETQNKTVFWNGIPIKNNLITLCQMLGTLGVWVRLHYVYPYPHVDDLIPLMAAGKILPYLDIPLQHASPKILKAMKRPGSVERVLERIKNWREICPELTLRSTFIVGFPGETEEDFQLLLDFLKEAQLDRVGCFKFSPVDGATATDMPDQVPEEVKEERFQRFMQLQQEISAARLQQKIGKTWKVIVDEIDEEGIIGRSMADAPEIDGVVYVDNVGQSAVRIGDIIDVRITRADEYDLWGTC
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPT1_PSOOV
Sequence: MKFVLAIASLLVLSVVYAYPSEIRTFEEFKKAFNKHYVTPEAEQEARQNFLASLEHIEKAGKGRINQFSDMSLEEFKNQYLMSDQAYEALKKEFDLDAGAQACQIGAVNIPNEIDLRALGYVTKIKNQVACGSCWAFSGVATVESNYLSYDNVSLDLSEQELVDCASQHGCGGDTVLNGLRYIQKNGVVEEQSYPYKAREGRCQRPNAKRYGIKDLCQIYPPNGDKIRTYLATKQAALSVIIGIRDLDSFRHYDGRTILQSDNGGKRNFHAINIVGYGSKQGVRYWIIRNSWDTTWGDKGYGYFVADKNLMGIEKFPLAAML
What is the function of this protein?
Probable thiol protease.
What are the official names of this protein?
Peptidase 1, Mite group 1 allergen Pso o 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAK5_CRYNB
Sequence: MAKIDKKTKLKLNKKSVRAPSKPTTEKKPKKYVTADTLTWKPVKTSSFSGIDGGGGMMMLEELEDVGIEWEETDGGRKIAKFVEVESKTSKGKKNAAQEEPNQEGRGDDEKASSASETEEGKKADDKEAVEEDDEEEFPDFAGFAEEDLNAADEEEHPNLDDEPAFNDDLLPEWSSISLHPSLKRSFLASSFTAPTAIQSRAIPAGITGRDVVGVAETGSGKTLAYSLPILHYLLGQRKSKAGIKRPLSALVLCPTRELALQVMDHLNALLKHALATPDGEKPQGPPRVSVGSVVGGLSAQKQKRILERGCDVIVATPGRLWDLIKADDELATSVRTLRFLVIDEADRMIENGHFAELESIVKLTQRSTAQQGPDDDDPVFQAMATLFEESTAREDMQTFVFSATLSKDLQKNLKRRSRSWKGKGKRSSTLEDLVEKLDFRDENPEVIDLSPEGGVVSSLRESMIESTKDDKDLYLYYFLLRYPGRSIVFVNSIDSIRRLLPLLTLLQLPVFPLHSHLQQKQRLKNLDRFKSNPKGILIATDVAARGLDIPQVDHVVHFNLPRTADAYIHRSGRTARAQNEGFALQLVSPDEKSVQRALMKSLERTHELPDLPIEAGFLPSLRERLRVATEIEKAQHRATKATHDKNWLLEAAEAMDIDIDPSMLDGEDDDPDAPYYKPKKQDRGKGKASVENLKMELKALLQEKLVARGVSIRYPTSGSKVIVDDLIKSTGHGMLLGASTSKAYDQVEKTGKRKLGSGRPGAVKKKKVEGR
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase MAK5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RNPH_THEP3
Sequence: MNRIDGREFNELRPIKITRNFNKFAEGSVLIEMGNTKVICTASIEDKVPPFQKGTGKGWITSEYGMLPRATETRNPREVTKGRPSGRTMEIQRLIGRSLRSVVDLDVLGEKTIWIDCDVIQADGGTRTASITGSFIALADALNKLVEKGDIPKIPLKGFVAAVSVGIVEGNELLDLSFQEDSNALVDMNVVMTDKGEIVEIQGTGEGGPFTKQNLTDLLSLAEYGIEQIIKIQKEVLSDIVDKIGVDSVENNNSNPQSSQN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PRIS_METAC
Sequence: MDKRTTQFLKSRFQSYYKNAEIGLPDHLPNREWAFIFYDDMPEKMMHRHKSFGSPGEALDYLYGMAPAHVYNSTAYYEYPDAKKMNEKNWLGAELIFDLDADHLPNAPRNYADMLELVKKEALKLLDFLLDDFGFSEQEIQLVFSGGRGYHFHIVSPKVLTLGSSERREIVNYVSGRDLEFKYFFREVAMDGDFGTGSKTFKGMKNVPMKCTLVGYDSGWGRRIALYLTDYMKRESEKKYKKDMFPELRRHEKVGDTTIKKLINIANSETGLKDILEKGRLDFDVRNFKEIAAYFMQESAEDFLHRFGASVDEPVTADIKRLIRVPGSLHGGSGMLVKKLALSELEEFDPLNDAVVFGERPVKITASKPFSVQLKGKDLRIEEGIQEVPEYAAVYLICRGVAEYGHRRNQPDTV
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: YCBL_BACSU
Sequence: MLVEDDHSISEMVDHYLTKEGFGIVHAFDGEEGIRLFQQGSYDLVLLDIMLPKLNGMDFLKIIREKSNIPVLMISAKDGDVDKALGLGFGADDYIAKPFSMIELTARVKAAIRRATQYSAEEPAVNKVIRIHQLAIDIDNVSVLKNGEPLQLTSTEWQLLCLFASNPKKVFTKEQIYRSVWNEEYFDDQNIINVHMRRLREKIEDDPSSPQYIKTLWGIGYKLGEF
What is the function of this protein?
Member of the two-component regulatory system YcbM/YcbL.
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein YcbL.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPH_SHIDS
Sequence: MNKFEDIRGVAFDLDGTLVDSALGLAAAVDMALYALKLPIAGEERVITWIGNGADVLMERALTWARQERATLRKTMGKPPVDDDIPAEEQVRILRKLFDRYYGEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGGDDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGEAIDLSQPDVIYQSINDLLPALGLPHSENQESKND
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: GET3_SCHJY
Sequence: MSLEPLPGTLENLLEQTSLKWIFVGGKGGVGKTTTSCSLAIQMSKVRKSVLLISTDPAHNLSDAFGTKFGKEARLIPGFENLSAMEIDPNASIQEMLEQSEQQNPNNPMSGMMQDLAFAIPGIDEALAFAEVMKEVKSMNFDCVIFDTAPTGHTLRFLNFPTVLEKALAKLSGLTSRFGPLINQMSGMLGTNTNQEDIFAKMEGMRGSISEVNKQFKNPDLTTFVCVCISEFLSLYETERMIQELTSYEIDTHNIVVNQLLLDPDTKCPQCIARRKMQQKYLSQIEELYEDFHIVKVPQVPSEVRGTEALTKFSDLLIHPYVKE
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase get3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: RS6_SHEB2
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGVITEANGTIHRLEDWGRRQLAYPILDLHKAHYVLMNVEAKAETIEELETAFRFNDAVLRNMVMRTKVAVTEASPMAKARDERDSRRGPAGERSYDEAHAEEIAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y5917_PSEFS
Sequence: MRVWIDADACPRAAKDQVVKFALKRQFEVVLVAGQSQIKPSFSCVKLIVVPSGPDAADDYLVEHAVPGELVICSDVPLADRLVKNGVTALDPRGKEFSPANMSERLAVRNLFTDLREQGQMGGGPPPHGEKEKQAFANALDRILTRLMRQA
What are the official names of this protein?
UPF0178 protein PFLU_5917.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.