PharMolix/UniProtQA huggingface dataset:
Protein: PDGFB_CANLF
Sequence: MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGASVDEDGAELDLNLTRSHSGDELESLSRGRRSLGSPTVAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPTFKKATVTLEDHLACKCETVVAARPVTRTPGSSQDLRAAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKKALKETLGA
What is the function of this protein?
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.  Potent mitogen for cells of mesenchymal origin.  Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta.  Required for normal blood vessel development, and for normal development of kidney glomeruli.  Plays an important role in wound healing.  Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
What are the official names of this protein?
Platelet-derived growth factor subunit B, PDGF subunit B, PDGF-2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
What are the subcellular locations of this protein?
Secreted. Note=Released by platelets upon wounding.
Protein: RBSD_SHIB3
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_ECO7I
Sequence: MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATRQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGETVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: RR18_CUCSA
Sequence: MDKSKRLFLKSKRSFRRRLPPIPSGDRIDYRNMSLISRFISEQGKILSRRVNRLTLKQQRLITIAIKQARILSLLPFLNNDKNDKQFERSESTPRTIGLRTRNK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEM3_CLOBH
Sequence: MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVKDIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAKIGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGVILAVAGLKRVNLDHLITDYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHSTIGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGISLAEHILKD
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: GSXL6_ARATH
Sequence: MTPPPNSISSRNVAVIGAGAAGLVAARELRREGHTVTIFERQKQVGGLWVCTPNVEPDLLSIDPDRTVVHSSVYQSLRTNLPRECMGYSDFPFVTRPDDESRDPRRYPDHREVMRYLQDFAKEFKIEEMIRFETEVFRVEPTAENSCKWRVQFRSSSGVSGEDIFDAVVICNGHFTEPRLAHIPGIESWPGKQIHSHNYRVSDPFKGQVVIVIGYQSSGSDISRDIAILAKEVHIAAKSDAYAKESSIYSNLHFHPTIDRVYEDGSVVFQDGKLIFADAIVHCTGYKYCFPFLETKGYVNVEDNRVGPLYKHVFPPALAPGLSFIGLPSMALQFFMFEIQSRWVASVLSGRVKLPSEEQMMEDVIAFYAKLKSLGIPKRFTHFLTDPQWTPMFEKLKPHEAVLISQSEYFNWIAEQCGCSSIERWREEQYNIAIKKDDDNFRDEWDDDDQIIQEAYRDFAKFKPSKVWST
What is the function of this protein?
Catalyzes the conversion of methylthioalkyl glucosinolates of any chain length into methylsulfinylalkyl glucosinolates.
What are the official names of this protein?
Flavin-containing monooxygenase FMO GS-OX-like 6, Flavin-monooxygenase glucosinolate S-oxygenase-like 6.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: K1H1_PANTR
Sequence: MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTPCVPPAPCTPCAPRPRCGPCNSFVR
What are the official names of this protein?
Keratin, type I cuticular Ha1, Hair keratin, type I Ha1, Keratin-31, K31.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: Y086_PSESM
Sequence: MSIRSWPAAERPRERLLELGAASLSDAELLAIFLRTGVAGKSAVDLARHLLNQFDGLRSLLDADQPAFTAQLGLGPAKFAQLQAVMEMARRHMAESLRRDSALENPAQVRNYLKAQLRHEPHEVFACLFLDNKHRVMTFEILFRGTINASYVHPRQVVKRALAHNAASLILCHNHPSGITTPSRSDIDLTKRLKEALKLVDVHVLDHVIVGDGEPLSMVEKGLM
What are the official names of this protein?
UPF0758 protein PSPTO_0086.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: GATC_LISW6
Sequence: MSNISKETVEKVANLAKLEVSEKEATAFAGQLGKIIELVEQLNTLDTNNVEPTSHAIDVSNVLREDVATKGLDRKEVLKNAPDEQDGMFKVPTIMEQ
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RNPH_GEOUR
Sequence: MRFDGRGAESLREVKITRNYLKHAEGSVLIEFGDTKVICTASVEGSVPPFLRGKGTGWVTAEYSMLPRATHTRSHRESSKGKVGGRTHEIQRLIGRSLRAVMDMNLLGERSVLIDCDVIQADGGTRTASITGAYVALYDALDGLVKKGELAAMPLKEAVAAVSVGIVDGTPLLDLNYVEDSSAEVDMNFVMTSSNRFVEVQGTAEAEPFTVEQMDAMRDLAISGIKRLFQIQKEALCQ
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: Y100_THEM4
Sequence: MFGLINIGFGNVIAGDRIVAIVNPESAPLKRLKEDAKEEGKLIDATYGRKTRAILISDSNHIILSAIQPETIAQRFMQSFFEIEEQLERIRRKG
What are the official names of this protein?
Putative regulatory protein Tmel_0100.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: KHSE_PROM3
Sequence: MAQPSIGQKIVVDVPSTTANLGPGFDCLGAALDLNNRFAMRRIEGDSGRFELIIEGNEGSHLRGGPNNLIYRAAQRVWKAAGLEPVGLEAKVRLAVPPARGLGSSASAIVAGLVGANALVGEPLSKEKLLELAIDIEGHPDNVVPSLLGGLCLTAKAASQRWRVVRCVWINSVKVVVAIPSIRLSTSEARRAMPKDIPISDAVENLGALTLLLQGLRTGNGDLITDGMHDRLHEPYRWPLIKGGLDVRDAALNAGAWGCAISGAGPSVLALCPEDKGQAVSQAMVKAWEAEGVASRAPLLSIQTGGSHWQPQIEDE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPOK1_PODCO
Sequence: MSDKDRIAQLLRELEEAKARVEEAKAREAQERCEKERLQLEHRKTTFLEYLRNCHRHLYNALRLTDTSRSSTGYTKVVGKYYPKRLRPWTNFANVLHPRYFDLVQKICGQRQLFEPASTTKNLGTIISDHLAGNEKAIDRFEVDAVERPVQAILKVLATHEEAGKAYRCPEFRFSANLRELTQEDDGSSGADDNTSDGSLERRQQAGPNKRPTSKRKYICSNRQPDGVGIRMQPGGGQTQAFIYDYKAAHKVAIEHVRSATAKEHLFHEVVARINDNKLSRDKEVQRREQAEAFIAMALTQVFDYMITYGVSYGYVAAGRCLLLLYVDRDDWQTLYCHPCLPADDVGEPTNDWTDRLSHTAVAQLVSFCLSSFQSEALEGQSLETALSVANATLKTWSESYADVAYLGLEPAELSSAPSSQNTDISEYTSKAKPTGRNVALRSQSSCKPAAVLPQGNEHDEHDEDHSEPGASRSRLAANKRKRGPSSGGEDEDIAMADPEPTRQYCTQACLLGLKRGKDLDENCPNVSLHRFDGSSRHPVNAHRFTDMVKQQLLLSPYKGCRMVDFWGKRGAMGWLFKLELFPYGYTFVGKGTLEDRLSRLEHEGRVYARLDHLQGDVVPVHLGLVRLDRGYILPGLEFVVYMMLMSWAGQTPSASMADAETLKRESLTAIWSEGVDHGDDNRANYLWNAERCRIMIIDFDRARLFPPLKPRAVSRLSKPKRERGNRSRHQIRT
What is the function of this protein?
Promotes unequal transmission of alleles from the parental zygote to progeny spores by acting as poison/antidote system, leading to poisoning of progeny that do not inherit the allele (PubMed:24830502, PubMed:31347500).  May possess DNA nuclease activity that leads to spore killing, and a kinase activity that confers resistance to the nuclease activity (PubMed:36537809).  Can suppress meiotic drive by the P. anserina SPOK2, SPOK3 and SPOK4 proteins (PubMed:24830502, PubMed:31347500).
What are the official names of this protein?
Meiotic driver SPOK1, Spore killer 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1271_MANSM
Sequence: MRQKIFLFVRSLIILYLILFIGEGIAKLIPIGIPGSIFGLLILFIGLTTQIIKVDWVFFGASLLIRYMAVLFVPVSVGVMKYSDLLVSHASSLLIPNIVSTCVTLLVIGFLGDYLFSLNSFTRLRKKAIKKRDINNVNNKGEAS
What are the official names of this protein?
UPF0299 membrane protein MS1271.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAY_ECO55
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMA_CUPNH
Sequence: MSGAGKRVVVGMSGGVDSSVTAWLLKQQGYEVIGLFMKNWEDDDDSEYCSTRQDWLDVVSVADLIGVDVEAVNFAAEYKDRVFADFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAETIATGHYARVRQNAAGRFELLKALDHTKDQSYFLHRLNQAQLSRTLFPLGEIPKTRVREIAAEIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPEGKVVGEHIGLAFYTLGQRKGIGLGGSREGNGDAWYVARKDMANNTLYVVQGHDHPWLLTPVLTASDLSWVAGEPPAAGAAMAAKTRYRQSDAACTVQAVDGDALTLRFAEAQWAVTPGQSAVLYDGDICLGGGIIQ
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_PHYAS
Sequence: MFAIIRTGGKQLRVSEGQEIFVEKLPINPEQNYEFKEVLAVYGEKSILGQPYVEGAKVQAQVIKNDRAKKIIVFKYKRRKKYRCKQGHRQAYTKLLITKIIA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CBID_PROA2
Sequence: MTAQKGELRQGYTTGSCATAAARAALHLLLDGQMPERVSITLPDGGSAEFSPEAGRRDAAGASCCVRKDAGDDPDVTNGLLVCCRVALLDDEPEGHIEFCRGEGVGMVTLPGLGIDVGGPAINPVPRSMIREALGGLLDRYGLRCGVQVTVSVPGGEEVARKTLNARVGVKGGISIIGTSGRVIPYSEEAYLESIARTIRVARHSGSTHLVACAGARSEKLLRRMYPDLPETAFIHYGNRVGSTLDMIQHDGGFRNLTVGVMLAKATKLAQGELDLSSRTVGLNPQFIEHLVRKTGYAEDVALEAKALELVRSLVDIVPFSSSEPLYRALAESCRRVCRNRFPSGGLEFVLMTMQDGCILCDEHGCRDV
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: NDBW2_LYCMC
Sequence: MKCKKQLLVIFFAYFLVVNESEAIFGSLFSLGSKLLPTVFKLFSRKKQRALMKRDLEDIMDP
What is the function of this protein?
Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S. cerevisiae.  Has insecticidal and hemolytic activities.
What are the official names of this protein?
Ponericin-W-like 32.2.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Medium-length antimicrobial peptide (group 3) family. Ponericin-W subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSV2_NEUCR
Sequence: MDTRRILEHPVLAPVLSVTFNHDNSCFAVGLDHGFRIYESGSCVLRTSRDFGAGIGMVQMLGRTNILGLVGGGRQTKLSRNKLVLWDDKSKKQVGVISASSLVRGAKMSSKRIVLVLMDRVQVYQTAKPHPLLSTYETTDNPLGLCCLSSDRIAFPGRAIGHVQLVEVETGNVSIITAHTSALRAMALSQDGELLATASEMGTIIRVYATSNCARLYELRRGIDKAIIFSIGFSPSGKYLACTSDKSTLHVFDVTRPGGTRPITSNGGTAYAAGEPSVTGNNRPSSPYSVASSSGGGGGVMVNSNNGGSDMAADDGQGRWGFLSKLPLMPRIFSDPYSFASAKFEMADEPVSNGSREPLTRDGGLAIIGGPLKGNLGWISETEMVVIGAGRDPKWEKFAIQEGGQQDGYQGGGRRLVRVGWKRYGGETP
What is the function of this protein?
Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways.
What are the official names of this protein?
SVP1-like protein 2, Autophagy-related protein 14.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Vesicular and vacuolar.
Protein: 17KD_RICS2
Sequence: MKLLSKIMIIALATSMLQACNGPGGMNKQGTGTLLGGAGGALLGSQFGKGKGQLVGVGVGALLGAVLGGQIGAGMDEQDRRLAELTSQRALETAPSGSNVEWRNPDNGNYGYVTPNKTYRNSTGQYCREYTQTVVIGGKQQKAYGNACRQPDGQWQVVN
What are the official names of this protein?
17 kDa surface antigen.
What is the protein family that this protein belongs to?
Belongs to the rickettsiale 17 kDa surface antigen family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DSBB2_PSEAB
Sequence: MPLASPRQLFLLAFLACVAIMGGALYLEHVVGLEACPLCVVQRIFFILIGLTCLAGAIQGPGLRGRRIYSVLVFLLALGGGATAARQVWLQTVPLDQLPACLPSLDYMMQALPFQEVIRLVLHGTADCAQVSWTLFTLSIPEWSLLAFVAYLGFSIVQFLRRA
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B 2, Disulfide oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSA_IGNH4
Sequence: MDRSLELFQIAKNLFPGGVNSPIRAAVKPYPFYVKKASGATLVTVDGVELIDYVLGYGPLILGHMHPKVLEAVEEQLNRGWLYGTPHELEIELAKKIVSHYPSIDMVRFVNSGTEATMTAIRLARGFTKKNKIIKFDGCYHGAHDSVLVKAGSAVSHFGVPGSAGVPEEVSKLTLVVPFNDVEAVEKVAKENQDDLAAIIVEPVMGNAGVIPPKEGFLKELRRIADETGALLIFDEVITGYRLGLGGAQAKFGVVPDLTTLGKIVGGGFPVGVVGGKREIMEYLTPSGPVFNAGTFNAHPVTMAAGLATINELERGYVYEVANSAAEKVAKALEQEAVAKFGGVVHRVASMFQWFPGVEEVNNYADALKANKEISLRLHEELLKRGVFIAPSLFEAWFTSAAHGEDVVNKTLEALSEALKVIS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM4_HUMAN
Sequence: MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHFKQEEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVTDRK
What is the function of this protein?
E3 ubiquitin-protein ligase.  Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor RIGI, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM4, RING finger protein 87, RING-type E3 ubiquitin transferase TRIM4, Tripartite motif-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_BURP6
Sequence: MTQQTMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALENNALYESDPNLRIRLSFDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDFQVDTIERAARGTTITLHLREGEDELLSSYRLKSIVQKYSDHVALPILMKKEEWDQEKGEMVEKDEDETINQASALWTRAKSEVTDEQYKQFYQHVAHDHQDPLAWTHNRVEGRSEYTQLLFVPSHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYLRFIKGVVDSSDLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWSAFGQVLKEGIGEDHANRERVAKLLRFASTHGDTDAQDVALADYVARMKPEQTKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHEFDGKPLASVARGDLDLGALNDDEKKAQEETGEAMKPVVDKMKETLGEKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRMLKAAGQSAPSFQPILEINPEHPLVKALKADGADFGDWCHLLFDQALLAEGGALEDPASFVKRTNALLLSRAA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF201_IIV3
Sequence: MNALINLKQSREYTTVTIDGQNHHIKLAGTMDDPYFCGKDVCSILRYKDVKQALQNKVKPKNKKMLSVLVKQDHNAVGVQTTSTRLGSNSPLTYNEGKAIYINEPGLYALIMHSNAPFAEEFQDLVYEQILPSIRKYGSYQLEMQLTQAMEQLSIKERDVQEAHEARIKAERKAVRVDKFMRRIAIKERKLEWIYIATTQQYAQERLFKIGSTSRLNTRIGHYNVGRPAEDSYYYCWVTKCYNSKDIDYHIQKLLVDFKHKNNAELYCSIKFSDLVAIVSFIVQHYDASIDYINSFIKTRLVASFDEEDGIPPAIDIRTSLANQGLVVDQDDIDVLIPQELNDSINEKVKQNLEEIVIERKELISKLADKTNISKKDLWTRIKDLTGWSSSKTVIINGDLNYKIIY
What are the official names of this protein?
Putative Bro-N domain-containing protein 019R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 201R/289L family.
Protein: RS2_VIBVY
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNRVHIINLEKTVPMFNEALAELVKVGEKKGKVLFVGTKRAASEAVKEAAIASNQYYVNNRWLGGMLTNYKTVRQSIKRLKELEVQSTDGTFDKLTKKEALMRTREMEKLEKSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAVVDTNSNPDGVDYIIPGNDDAIRAVQLYLNAAASSLTEGRNKDVAAVAEKDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SGF11_KLULA
Sequence: MTASLTTDSVADSIYQNILTSIIQDIISRQTVKRKLLKLQFPDAKPYYADPSGTLDIHGKAKQADSAVYIECNVCGREVSGNRFAAHLVRCLSRGRR
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  Involved in transcriptional regulation of a subset of SAGA-regulated genes.  Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
What are the official names of this protein?
SAGA-associated factor 11.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RKPI_RHIME
Sequence: MKWLKGIGLALIPFNLHDYPIALTLGCYLLSCAVIFYTDRFALPARERRKNAPKYGRNRDRIDRLARLPVIALVFAGFFAISWRPLYAAAGTMSFFIIFTGISRAKFKFIREPLVFSDIALVADVFKYKTIFYASSLNIVFWIVAFLYVFGVSALYMYFEPTILPERSRLFWVLVMVGIAAGPWGLLFYGPVNRPTAALVQRLVKAINVKMNTVRFGTFASVVFHFIIWLGVKRDKIVAELSEILRAAVHDLIGHEEAPLIIVWQSESFIDMRHFGVDSIKLPTVDRLRKQAVQWGRLSNVFEGGYTLRTEFAVLSGLVPDDIHVDASYPYLRAAHYADIVWPGKLKRAGWRTHFIHPYDRTFFLRHKAMPLLGFEKLTMLDAFDHKPERDGLYVSDATLAARVLAEVEKLPEEESGFFFVASMANHGPWEPGRVGTLTNPVDIYLAILEQSDAALKQLIDGLNKLDRPVWFVFYGDHAPLLKSFADPFPDPRTDYFIVPLAKARAAAHSPKRAKDEDPWNLLGSMLKHANLHKDALQ
What is the function of this protein?
Involved in antigen K (capsular polysaccharide) biosynthesis.
What are the official names of this protein?
Capsular polysaccharide biosynthesis protein RkpI.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRPE_RHIRD
Sequence: MTDDTKKPGPDADVAEEFVDPAQAGEEQAETAEPDPVELLKAENADLRDKFLRLAAEMDNLRRRTERDVKDAKAYSLAGFARDMLAVSDNLRRALEAIPDELKTNGEAGLNGLIEGVEMTERSMLSTLERHGVKKIDAEGQKFDPNFHQAMFEVPNTAVPNNTVLQVIQAGFTIGDRVLRPAMVGVAKGGPKAEPSASAEPGTSSLNEKDA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRNQL_STAAM
Sequence: MNKNTWVIGFTLFAMFFGAGNLIFPPNLGLDSGQFFWPAILAFVLTGIGLPLLGVIVGALDKEGYIGALNKISPKFSILFLIIIYLTIGPLFAIPRTASTSFEMTITPIIHSNSSIALFIFTIIYFIVVLYICLNPSKLIDRIGSLLTPLLLITILAMIIKGYLDFSGNSAGKGNEALYHSNFSSFAEGFTQGYLTMDAIAAIAFSMIVVNAVKLTGITKTNQIFKQTLTAGLIAAVALIFIYISLGYIGNHMPVSDMTLDQLKSKDRNIGTYLLTTMASTGFGSFGKYLLGIIVALACLTTACGLIVAVSEYFHRIVPKVSYKAFVLVFILMSFIIANQGLNAVISMSIPVLSIVYPVAITVVLLILIAKFIPTKRISQQIPVIIVFILSIFSVISKLGWLKINFIESLPLRAYSLEWFPVAIIATILGYLVGIFVKQDPIKYQQE
What is the function of this protein?
Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine), which is coupled to a proton motive force (Potential).  Contributes to NaCl tolerance (By similarity).
What are the official names of this protein?
Putative branched-chain amino acid carrier protein SAV1407.
What is the protein family that this protein belongs to?
Belongs to the branched chain amino acid transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.