PharMolix/UniProtQA huggingface dataset:
Protein: RS23_LUMRU
Sequence: MGKPRGLRTARKLKNHRREQRWHDKDYKKSHLGTRWKSNPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPRDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKQKKERPRS
What are the official names of this protein?
40S ribosomal protein S23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: ODP2_RHIME
Sequence: MPINITMPALSPTMEEGNLAKWLVKEGDKVKSGDVIAEIETDKATMEVEAVDEGTVAKIVVPAGTEGVKVNALIAVLAAEGEDVATAAKGGNGAAGAVPAPKPKETAETAPAAAPAPAAAPAPQAAAPASPAPADGEGKRIFSSPLARRLAKEAGIDLSAIAGSGPHGRVVKKDVETAVSGGAAKPAGAPAAAPAPATLAKGMSEDAVLKLFEPGSYELVPHDGMRKTIAKRLVESKQTIPHFYVSVDCELDALMALRAQLNAAAPEKDGKPVYKLSVNDMVIKALALALRDVPDANVSWTDQNMVKHKHADVGVAVSIPGGLITPIVRQAELKSLSAISNEMKDLGKRAKERKLKPEEYQGGTTAVSNMGMMGVKDFAAVVNPPHATILAVGAGEDRVVVRNKEMVIANVMTVTLSTDHRCVDGALGAELLAAFKRYIENPMGMLV
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: MACB_AROAE
Sequence: MPLIELSGVTKTFRNGELAVEVLHGIDLTILPGEFVAIVGSSGSGKSTLMNILGCLDRPTSGSYRFMGRNVAAFDRDELALLRRETFGFVFQSYHLIGGASARENVEVPAVYSGMPPAERHARATGLLASLGLGERIEHRPNQLSGGQQQRVSIARALMNGGRVILADEPTGALDTKSGAEVMQLLNKLSADGHTIILITHEREVAEQAQRIIEIRDGRIVADPGPRPRSGLEPDFAPHVDRTSPLSDIVEAARTALRALRANIFRAALTLLGIVIGVAAVIAMLAIGDGAKQDVVDRISSMGTNLLTVRPGAPNQRGRDTTATLVLDDVRAIRDLPNVLAAVPEQSSTVTIRSGNADHRTSANATGADFTLARAWPIARGTFFGAADERSYATVAVLGQTVAKALFGDADPVGEFVLVNSIMFQVLGVMGPQGATPWGTDQDDVIFVPYSTGSLRLFGQRHLRNATIAVEDVAAIDDTQAAVHELLQARHGGIEDFQIRNMASVIESVSETQNTLTVLLGTVAAISLLVGGIGVMNIMLVSVTERTREIGIRMATGARMKNILQQFLIEALVVSALGGVIGVVVGLGAAAIIEAFDTPIVYSAPPVLLAFGCAFATGLVFGYLPARKAARLDPVVALASE
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRS10_MOUSE
Sequence: MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4, Proteasome 26S subunit ATPase 6, Proteasome subunit p42.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SWT12_ORYSJ
Sequence: MVQALVFAVGIVGNILSFLVILAPVPTFYRVYKKKSTESFQSVPYAVALLSAMLWLYYALLTSDLLLLSINSIGCLVESLYLTVYLLYAPRQAMAFTLKLVCAMNLALFAAVVAALQLLVKATDRRVTLAGGIGASFALAVFVAPLTIIRQVIRTKSVEFMPFWLSFFLTLSAVVWFFYGLLMKDFFVATPNVLGLLFGLAQMVLYVVYKNPKKNSAVSEAAAAQQVEVKDQQQLQMQLQASPAVAPLDVDADADADLEAAAPATPQRPADDDAIDHRSVVVDIPPPPQPPPALPAVEVA
What is the function of this protein?
Confers blight susceptibility (PubMed:25988582).  Confers TAL effector-mediated susceptibility to Xanthomonas oryzae pv.  oryzae (PubMed:23879865).
What are the official names of this protein?
Bidirectional sugar transporter SWEET12, OsSWEET12.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADA_NEIMF
Sequence: MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETAGRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEADTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK3_LUCVE
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, LucVe-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DOCK3_MOUSE
Sequence: MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGLFPANYIHLKKAIVSNRGQYETVVPLEDSIVTEVTTTLQEWASLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGETCRMPVPYHFFFSLKSFTYNTIGEDSDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGHCPVTAEITGEYVSCLLSLLRQMCDTHFQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELIDKLDSMVSEGKGDESYRELFGLLTQLFGPYPSLLEKVEQETWRETGISFVTSVTRLMERLLDYRDCMKGEETENKKVGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYESLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKDNEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYITKHPGDAEKISQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMMMMGDNSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRGSPSLPDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKGHYSLHFDAFHHPLGDTPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEGLEPPYLPVHYSLSESAVLDAIKSQPCRSHSAPGCVLPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSVKEEQARLAWEHGRGEQ
What is the function of this protein?
Potential guanine nucleotide exchange factor (GEF).  GEF proteins activate some small GTPases by exchanging bound GDP for free GTP.  Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease.  Ectopic expression in nerve cells decreases the secretion of amyloid-beta APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors.
What are the official names of this protein?
Dedicator of cytokinesis protein 3, Modifier of cell adhesion, Presenilin-binding protein, PBP.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMH_HAEIN
Sequence: MKKTWLFLTALLFSSVAFSAIDALNFSSPQQESDYHQLTQSLRCPQCQNNNIADSNATIAVDMRGKVFELLQEGKSKNDVVDYMVARYGNFVTYDPPITASTLVLWIAPLLLVLLGVVFLLRRKPKTQSAVKSQEILTDEDNARLAELLNKDKXMNFTLIFILTTLVVALICFYPLLCQFKAKHGQKRDDLNKALYFSRLEEIEQDNSQGLVENVEQLKQELQKTLLDDVPSKVQENVDYSGKSYGKIWFISGVLALGIIAGPSYFMVGSWQAESMLEQTYAKLPYFFDRMKNEDKNPFSDTEMQQFSTALRIDLQKNPTDAKKWWMLGQIGMNLGDARLAFDSYQKANKLEPDNVQYKLGYARILMFSEDATDKLKGGNLLREVIRQEHTNIEALSLLAFRYFETEDYKMAAVTWAMMLRLMPKDDERVPLIEKSIRTARDALEAQNEEKSKSITPEK
What is the function of this protein?
May be required for the biogenesis of c-type cytochromes.  Possible subunit of a heme lyase (By similarity).
What are the official names of this protein?
Putative cytochrome c-type biogenesis protein CcmH.
What is the protein family that this protein belongs to?
Belongs to the CcmH/CycL/Ccl2/NrfF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL13_PECAS
Sequence: MKTFTAKPETVKRDWYVVDANGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKIYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGTEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NADA_ECO55
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQSIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_LEGPH
Sequence: MFNRIISLFLLLFTGQVIALDLELTQGINSALPIAINSFGSNAAAQEIGNVIENDLTISGQFKIISGPQGANSQSSVSTLRQLGADSVVTGRVNQVGNRIEVSFTLADAVANGNILLTKTFQINANQVRALAHHISDEVYQKLTGERGIFSTRIAYISVQRNGGRSRYSLEVADADGHNPQSLLVSSEPIMSPSWSPNGKSISYVSFEKKKAEIFTVSVETGQRRLITSFPGINGAPAWSPDGQHLAVVLSKSGTPKIYDVDLSSGSMKQLTFGNSIDTEPRYSPDGRSLLFTSGRGGSPQVYRLSLADGQISRVTFEGNYNARASYTPDMKHIVMLHREDRQFNIGVQNTGGGPISNLTFSGLDESPSVSPNSRLVLYATRYQDRGVLGIVSIDGRIRMRLPAREGDVQEPAWSPYLS
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YIDC_PECCP
Sequence: MDSQRNLLLIALLFVTFMLWQAWETDKNPPATTQAIQQATNAVTGDATNQGVPASGQGKLITVKTDVLSLTINTRGGDVEQAHLLAYPDTLGSDKPFHLLETTSEFVYQAQSGLTGKNGPDNPANGPRPLFTTTQDSFELADGQNELRIPMTYTAADGVTYTKTFVLKRGDYALNVDYSVNNTSAQPLELTLFGQLKQSIDLPKHRDTGSSNFALHTYRGAAFSSSEDKYKKYSFSDMDENLNITTNSGWVAMLQQYFATAWIPTTAGANTFYTNKLGNGQAAIGFKAAPVVVAAGSQQNLNATLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKFLHGFIGNWGFSIIAITFIVRGVMYPLTKAQYTSMAKMRLLQPKLQAMRERIGDDKQRMSQEMMALYKSEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTYMPVIFTVFFLWFPSGLVMYYIVSNLVTILQQQLIYRGLEKRGLHSREKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYV_PARUW
Sequence: MTELPKAYEAKKIDEKWYQFWDAKRYFTANPLSNKPTYCIVIPPPNVTGVLHMGHALVNTVQDILIRWKRMLGFETLWVPGTDHAGIATQMVVERHLIKTEGKKRTDYTREEFLKHVWTWKEKSENRIIEQLKRLGNSCDWTRLRFTMDENNSLAVRTMFKKLFDDGLIYRGDYLVNWDPHTQTALADDEVEYEDKQSFLWYFKYPLRDESEFISIATTRPETMLGDTAVAVSPNDERFKHLIGKEIRLPLMNRLIPIIADHHVDPSFGTGVVKITPAHDPNDYQIGLSHRLPFINIMTPDGKINENGGHFQGLSMTEARHAVVSEMKEKGLLEKVEPHLNRVGISYRSKAIIEPYLSKQWFVKMDGFSKKLREVVQNGQVKLIPSHWESTYFHWIDNLRDWCISRQLWWGHRIPIWYHKEDSNRLICYAGSDLPDEVKNAPEEWIQDSDVLDTWFSSALWPFSTLGWPEQTSELAKFYPTSVLVTGHDILFFWVARMILMGDYALDQPPFPETYLLGLIYGKSYWRQESNGGILYVNEQERSDFDMGKPIPKEVFSKWEKMSKSKGNIIDPLEMIDQFGTDAVRMALCASATQARQIDLDRRRFEEFKNFTNKIWNGARFVLMNLDGNEQNRTMSLTSQGFSQGLDEALFTLEDRWILSVLNRTVESVNVHLNHYQFDQAAIEAYDFFWKEFCAYYVEIAKPILFGKIGTAQERTNKQKLLVIVLCQAIRLIHPMAPFITEELFHILKERLEGVEALTNADPYTKECIQALQSSACLVAPYPVRIGEKNQKVEAVFALMEQIVYTIRNIRGEMKLSPGTATDVYIIGQADDPEWQSAREHITMISALVKTRRILVETEEPKIGFACTGVYHALKIQLPLPEELLKQEKTRLNKEQEKLEISLEKLKNQLSNTDFVRRAPAHLTEKQNQQLSQTEQELREIKEKLMTLP
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMM1_CRYNJ
Sequence: MSETFSPNLTFTEGFVLGQASFLIILLLFIRYVVFSPSEQIDHEGWRKRRAERADLLSNHTPPPLSNLLSKTSYDMSIHPAESSDWVNVLLAQILQGYRNDLLSEGGEEGARQRIEGWLNPKGENLSWLDPIDVTSLSLGTSYPLLSNARIRPADGQGRLRAEIDVDYLDSLSMTLSTAVLVNFPKPRFAVLPVTLGVELVSIGGTMSVQLHEPIEDRQHIHVNLLPDFHLNLKVTSLLGSRAKLQDIPKLEQLIVSRLRNLVQDRFVHPNHISLALPRILSPSVSSTPILEGLGEGAVDAMKDAVSDGMKRMVEDFMGENPVEGALNGQGEEQWLDDDFPPTPLVQPPGTFPTLSVSSRQSHRQSLPPSRPQSTTQGQPQLFYRRPLIHPTQSYPHYNTYTLDPQIPHSVSYRHPPRGSHVHNPPETPVPQRPSHGQGRMSTTSSLTPSQSQSQFRFRGQFASGVTPGQVGTSR
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: LIMNS_PICSI
Sequence: MSPVSAIPLAYKLCLPRSLISSSRELNPLHITIPNLGMCRRGKSMAPASMSMILTAAVSDDDRVQRRRGNYHSNLWDDDFIQSLSTPYGEPSYRESAERLKGEIKKMFRSMSKEDEELITPLNDLIQRLWMVDSVERLGIDRHFKNEIKSALDYVYSYWNEKGIGCGRDSVVADLNSTALGFRTLRLHGYNVSSEVLKVFEDQNGQFACSPSKTEGEIRSALNLYRASLIAFPGEKVMEDAEIFSSRYLKEAVQKIPDCSLSQEIAYALEYGWHTNMPRLEARNYMDVFGHPSSPWLKKNKTQYMDGEKLLELAKLEFNIFHSLQQEELQYISRWWKDSGLPKLAFSRHRHVEYYTLGSCIATDPKHRAFRLGFVKTCHLNTVLDDIYDTFGTMDEIELFTEAVRRWDPSETESLPDYMKGVYMVLYEALTEMAQEAEKTQGRDTLNYARKAWEIYLDSYIQEAKWIASGYLPTFQEYFENGKISSAYRAAALTPILTLDVPLPEYILKGIDFPSRFNDLASSFLRLRGDTRCYKADRARGEEASCISCYMKDNPGSTEEDALNHINSMINEIIKELNWELLRPDSNIPMPARKHAFDITRALHHLYKYRDGFSVATKETKSLVSRMVLEPVTL
What is the function of this protein?
Monoterpene synthase (mono-TPS) involved in the biosynthesis of monoterpene natural products (PubMed:16415217).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) into (-)-limonene (PubMed:16415217).  Not able to use geranylgeranyl pyrophosphate (GGPP) and farnesyl pyrophosphate (FPP) as substrates (PubMed:16415217).
What are the official names of this protein?
(-)-limonene synthase, chloroplastic, PsTPS-Lim.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPXK_VIBPA
Sequence: MVEKIWFENHPLKYLLWPLLWPLSVLFGAISRSKRQQFQTGRKQAYQAPVPVVVVGNITAGGNGKTPVVVWLVEQLQHLGYKPGVVSRGYGAKAPQYPLVLNDDTPTQHCGDEPKLIHRRTGAPVAVDPVRANAVKALVELDVDIIITDDGLQHYALERDVELVIVDGNRRFGNECLIPLGPLREGVERLQEVDFIITNGGLAHQGEISMSLAPSKAINLKTKQQVDVSELKALVAFAGIGHPPRFFNTLESMHADVKVTKGFADHQDFDQKELEALALQGANVIMTEKDAVKCSDYAQDNWWYLPVSAQLEPKDAERILNRIKEVKATYGSPSA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RPOB3_ENTFC
Sequence: MKSLAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEGLGEMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRETGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGSTVIPNRGAWLEMETSAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLRNTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVGRYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSVTYYPSEDGVVTDPMTVQVIKVFSPKDPEREVNVIGNGYPESAVKTVRPADIIASMSYFLNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQQLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQIDYLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKHDGVVEFVDASEIRVRRDNGALDKYAVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLADGPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDTKLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRKIHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHLGMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTILYDGRTGEPFDGRVSVGVMYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIKDSEIQLRDMDDQDDDLITVNALTKFAEQQTAKELEKKAAEQVEDERQDIIQNFETAEDNLD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: OTO1A_DANRE
Sequence: MPNILHPFIIIMTLLVVATGNQASIDKTTQWPRMKPTKKPPPRDEGPSKLGSISTTVSPTAIGITEEVTDAMMDAYTITSTGSTTFSSDTYSADYHTEAMVPPGVGPGNYTLDYNECFFNFCECCPPERGPPGPVGEKGLPGIPGGKGEMGPPGPPGQEGLTGAPGTHGVKGEKGDTGASGLPGIPGVTGKQGEKGESGPKGDKGDTGFPGLKGDPGERGEPGWNGTKGGMGEPGKQGLTGPPGPDGIKGEKGDKGDCPFGEKGQKGSIGEPGPQGPKGDPGVPGTNGTDGLPGSKGPKGDPGPLSKQGEPGPPGPQGPPGQRGMPGMKGTRGLKGARGIRGFKGFKGEPAVQKRSAFSVGLFPSRSFPPPGLPIRFDKIIYNEEAHWDPNASKFNCTHGGVYVFSYYITVRNRPLRAALVVNGIRKLRTRDSLYGQDIDQASNMAVLRLSSGDQVWLETLRDWNGVYSSSEDDSTFSGFLLYADATKD
What is the function of this protein?
Collagen-like protein, which provides an organic scaffold for otoliths onto the sensory epithelium of the inner ear (PubMed:15905077, PubMed:29076638).  Acts as a scaffold for biomineralization by sequestering calcium (PubMed:29076638).
What are the official names of this protein?
Otolin-1-A, zOtolin1.
What is the protein family that this protein belongs to?
Belongs to the OTOL1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Localized in both the surrounding otoconial matrix and otoconia.