PharMolix/UniProtQA huggingface dataset:
Protein: ALG1_HUMAN
Sequence: MAASCLVLLALCLLLPLLLLGGWKRWRRGRAARHVVAVVLGDVGRSPRMQYHALSLAMHGFSVTLLGFCNSKPHDELLQNNRIQIVGLTELQSLAVGPRVFQYGVKVVLQAMYLLWKLMWREPGAYIFLQNPPGLPSIAVCWFVGCLCGSKLVIDWHNYGYSIMGLVHGPNHPLVLLAKWYEKFFGRLSHLNLCVTNAMREDLADNWHIRAVTVYDKPASFFKETPLDLQHRLFMKLGSMHSPFRARSEPEDPVTERSAFTERDAGSGLVTRLRERPALLVSSTSWTEDEDFSILLAALEKFEQLTLDGHNLPSLVCVITGKGPLREYYSRLIHQKHFQHIQVCTPWLEAEDYPLLLGSADLGVCLHTSSSGLDLPMKVVDMFGCCLPVCAVNFKCLHELVKHEENGLVFEDSEELAAQLQMLFSNFPDPAGKLNQFRKNLRESQQLRWDESWVQTVLPLVMDT
What is the function of this protein?
Catalyzes the addition of the first of nine mannose moieties to form a dolichol-lipid linked oligosaccharide intermediate required for proper N-linked glycosylation.
What are the official names of this protein?
Chitobiosyldiphosphodolichol beta-mannosyltransferase, Asparagine-linked glycosylation protein 1 homolog, Beta-1,4-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase, Mannosyltransferase-1, MT-1, hMat-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NUOB_BURO1
Sequence: MSIEGVLKEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDLDRFGVVFRPSPRQSDVMIVAGTLCNKMAPALRRVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGVIQLQAKIRRTNTIARQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
Protein: SECA1_LISIN
Sequence: MAGLLKKIFESGKKDVKYLERKADEIIALADETAALSDEALREKTVEFKERVQKGETLDDLLVEAFAVAREGAKRALGLYPFKVQLMGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALSGEGVHVVTVNEYLAHRDAEEMGVLYNFLGLSVGLNLNALSSTEKREAYACDITYSTNNELGFDYLRDNMVVYKEEMVQRPLAFAVIDEVDSILVDEARTPLIISGEAEKSTILYVRANTFVRTLTEEEDYTVDIKTKSVQLTEDGMTKGENYFDVENLFDLENTVILHHIAQALKANYTMSLDVDYVVQDDEVLIVDQFTGRIMKGRRFSEGLHQALEAKEGVTIQNESKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFRDIYNMRVIEIPTNKVIIRDDRPDLIFTTIEAKFNAVVEDIADRHAKGQPVLVGTVAIETSELISSKLKRKGIKHDVLNAKQHEREADIIKNAGERGAVTIATNMAGRGTDIKLGEGTIDAGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTQFYLSMEDELMRRFGSDNMKSMMERFGMAEDAIQSKMVSRAVESAQRRVEGNNFDSRKQVLQYDDVLRQQREVIYKQRYEVINAENSLREIIEQMIQRTVNFIVSSNASSHEPEEAWNLQGIIDYVDANLLPEGTITLEDLQNRTSEDIQNLILDKIKAAYDEKETLLPPEEFNEFEKVVLLRVVDTKWVDHIDAMDHLRDGIHLRAYGQIDPLREYQSEGFEMFEAMVSSIDEDVARYIMKAEIRQNLEREQVAKGEAINPAEGKPEAKRQPVRKDQHIGRNDPCPCGSGKKYKNCHGKEA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: CA087_MOUSE
Sequence: MSSPWKTSQSSVPMPEMIVKIVGSKHFRYFIEKPMNKQNEKLKTEPQTSLQKPRNDYSRRVSRDLPGPTDSSEQQITANPAEKEESKHQRSSLKPESNQKFLTRVFSNRFLDGRISYEANVHCSSVPTGDQSLSYMHSLPRRKSVGWCLEHTAKDSSGQAEEIVQRPSVMTREDSFLTTLVRRELNSRPLSSNLLDKLQKELKTLDPISSGFLHQSQLSCLFLRHKVPLPLLTVKLLCQRFSRRCSPEMVNYGEVLCFLKEATKDNLQQNGTAGYSNSRKTSSPSYHKQSIPPQDSSLLSEVNKSLLEILKMALRPCQGKLSIDCLNMSFRKEDHSFSGCLPLPKVISICSKHGLYVTMTLLETLLHHQELGYRGEIKWKNFVKWLNRASADLSCDMPAGKNKKETQGDLVDIPERPQRKTEHVKTPEENLQTKNPTTMTSAPEDPVTFFKNRPVSQPVEHLAVKKDGQSELWIDRFRKLENALYLCDLSNTGVLERERARRLIHNYNLIYSLSLSPRRINQALQRYRSGENIILEPALQYLKEL
What are the official names of this protein?
Uncharacterized protein C1orf87 homolog.
Protein: Y796_YERPP
Sequence: MSEPLKPRIDFEQPLQSLDEPVLKSAQAFDEQAAEKFYPAAPELDAEDEEGRVEGLVNAALKPKRSLWRKMVTAGMVILGASVIAQSVQWVNQAWQQQDWIALGATTAGGLIILAGVGSVVTEWRRLYHLRQRAEERDIARALLVSHGVGQGRVFCEKLARQAGLDQGHPALQRWQASLHETHNDREVVELYAKLVQPALDNQARAEISRYAAESALMIAVSPLALVDMAFIAWRNIRLINRIAALYGIELGYFSRIRLFRLVLLNIAFAGASELVREVGMDWLSQDLAARLSARAAQGIGAGLLTARLGIKAMELCRPLPWLEGDKPKLGDFRRQLMNQLKNTLPKKDKTAH
What are the official names of this protein?
UPF0283 membrane protein YPDSF_0796.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RFBX_SHIDY
Sequence: MKKNILLLFLVHGANYLFPFIVLPYQTRILSIETFADVAKIQAAVMLLSLIVNYGYNLSSTRAIARAVSQAEINKIYSETLIVKLLLATICLALGCVHLMYVKEYSLIYPFIISSIYLYGSALFATWLFQGLEKMKAVVIATTIAKLTGVILTFILVKSPNDIVAALFTQNIGMFISGIISIYLVRKNKYATVICFRLKNIIVSLKEAWPFFLSLAATSVYTYFNVILLSFYAGDYVVANFNAADKLRMAAQGLLIPIGQAVFPRLSKLEGYEYSSKLKIYAIRYAIFGVCISAGLVFLGPMLTTIYLGKEYSLSGEYLQSMFLLPATISISTILSQWMLIPQGKEKILSRIYILGAIVHLLYAFPLVYYYGAWGMVISILFTEVLIVLFMLKAVK
What is the function of this protein?
May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units.
What are the official names of this protein?
Putative O-antigen transporter.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL3_PETMO
Sequence: MKGILGKKVGMTRVFKDDKAIPVTVIKAGPCVVVQKKTVETDGYNAIQIGFEEIPERKANKPLMGHFKKAQVKPLRYLREFRVENVDDYEIGQKIDVTIFSEGEKIDLIGNSKGRGYSGVMKRWNFRGGENTHGSKFHRGLGSTGMATFPSKVFKGKKMPGQYGNERVTIQNSEVVYIDVQNNLIAVKGGVPGARGGLVTIREAVKAKRPKTK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y1710_COREF
Sequence: MNQTPGSTVPETATPVTSPASSPSAPETTFTPVIITGMSGAGLSTAARVLEDLGWFVTHNLPPQMILPLVEMCAREDSPVDKVAVVCDVRSREFRGGLRETITELEEKNLAPTVLFLDARDDELIRRFDNVRRTHPLQGSQTLQVGIERERQMLSDLKEEADVVIDTSELSVHDLRRAIESSFRTIAKRVQHVTIESFGFKHGSPRDADFIIDARFLPNPFWVPELRPFRGVDKPVSDYVLSQKGAGEFLDNFIAMLDDMLPGYRHEGKNFITVGIGCTGGHHRSVAVSEELARRLGERPDLDVSVVHRDINRN
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein CE1710.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: HSCA_PSEA7
Sequence: MALLQIAEPGQSPKPHERRLAVGIDLGTTNSLVAAVRSGVAEPLPDARGRLILPSAVRYHADRAEVGEGARAAAAQDPLNTIISVKRLMGRGLEDVKQLGEQLPYRFRQGESHMPFIETVQGLKSPVEVSADILRELRQRAETTLGGELVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAVAYGLDKGAEGLVAIYDLGGGTFDISILRLTRGVFEVLATGGDTALGGDDFDHAVAGWVIEQAGLSADLDPGRQRELLQIACAAKERLTDATSVSVSYGDWRGELSRAKLDELIEPFIARSLRSCRRAVRDSGIDLEEIRSVVMVGGSTRVPRVRSAVGELFGCEPLTDIDPDQVVAIGAAIQADALAGNKRGEELLLLDVIPLSLGLETMGGLMEKVIPRNTTIPVARAQEFTTYKDGQTAMMIHVLQGERELVKDCRSLARFELRGIPPMVAGAAKIRVTFQVDADGLLGVSARELSSGVEASIQVKPSYGLTDGEIARMLKDSFDYAGDDKAARALREQQVEAQRLLEAVQSALDADGERLLDEEEHLAIAAQMDSLRELAGGSDTAAIENQIKRLSQVTDAFAARRMDATVKAALSGRRLNEIEE
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y4391_ARATH
Sequence: MEIRKKPNIFTVLVIDFSSKPSMALLLAILLFLSGPSASAVAAAAVGPATGFKPADDILIDCGSKSSSKTPDGRVFKSDQETIQYIEAKEDIQVSAPPSDKVASPIYLTARIFREEATYKFHLTRPGWHWVRLHFLAFPNDKFDLQQATFSVLTEKYVLLHNFKISNNNNDSQAAVQKEYLVNMTDAQFALRFRPMKSSAAFINAIEVVSAPDELISDSGTALFPVIGFSGLSDYAYQSVYRVNVGGPLIMPQNDTLGRTWIPDKEFLKDENLAKDVKTTPSAIKYPPEVTPLIAPQTVYATAVEMANSLTIDPNFNVSWNFPSNPSFNYLIRLHFCDIVSKSLNDLYFNVYINGKTAISGLDLSTVAGNLAAPYYKDIVVNATLMGPELQVQIGPMGEDTGTKNAILNGVEVLKMSNSVNSLDGEFGVDGRTTGMGKHGMVATAGFVMMFGAFIGLGAMVYKWKKRPQDWQKRNSFSSWLLPIHAGDSTFMTSKGGSQKSNFYNSTLGLGRYFSLSELQEATKNFEASQIIGVGGFGNVYIGTLDDGTKVAVKRGNPQSEQGITEFQTEIQMLSKLRHRHLVSLIGYCDENSEMILVYEFMSNGPFRDHLYGKNLAPLTWKQRLEICIGSARGLHYLHTGTAQGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNHVSTAVKGSFGYLDPEYFRRQQLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLAEWAMQWKRKGLLEKIIDPHLAGTINPESMKKFAEAAEKCLEDYGVDRPTMGDVLWNLEYALQLQEAFTQGKAEETENAKPDVVTPGSVPVSDPSPITPSVTTNEAATVPVPAKVEENSGTAVDEHSGTAMFTQFANLNGR
What are the official names of this protein?
Probable receptor-like protein kinase At4g39110.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DENR_ASPNC
Sequence: MAEVAQPVPAESQAKHVVYCGVCTLPPEYCEFGGTAKKCEEWLKDAHPDMYQSLYSEEALNSNLATLSVSARERAAKDAAKKEAKAAAAEARDAERKAASKVQIKRVERNKRKHVTVITGLDIYGLENKKIAKDLGKKFATGSSMTRSAGGTEEITVQGDVSDDVKEWLLEVYGKEIPEANIELIEDKKKKKATEAP
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_LATSS
Sequence: MTEKYILAIDEGTTSTRSIIFNHDGQKVADAQREFPQYFPEPGWVEHNANEIWNAVLSTIANAFIKSGIQPNQIAGIGITNQRETTVIWDKATGLPIYNAVVWQSRQTNDIAEKLKTDGYEDLIHKKTGLIVDAYFSATKIRWILDQVPGAQERAEKGELLFGTIDTWITWKLTGGATHVTDYTNASRTMIFNIHDLDWDDDILKLLNIPRAMLPDVRPNSEVYGETASYHFYGSSVPISGMAGDQQAALFGQLALQPGMVKNTYGTGSFIVMNTGEKPTMSENNLLTTIGYSINGKVNYALEGSVFVAGSAIQWLRDSMQLVEKSSDSEAAAKASTSLNEVYVVPAFTGLGAPYWDAEARGSILGITRGTNRQDIIKATLQSLAYQTRDVVQTMQKDTGIDIKMLRVDGGAANNNYLMQFQADILNSAIEKAANLETTAMGAAFLAGLAVGFWQDTDELAQIFSVGQRFEPNMPEEEREDLYAGWQQAIEATKIFKHRPYKMNE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y5912_BACAA
Sequence: MSTILVLGGSNGRTLEKLAKKRDCQVIFHDGKNHGGVKKTFRSVIKKCDVIVIQKGACGHVSIDVAKEYAKKYDVPLLFNQGFGGTGALEMGLKHLKAA
What are the official names of this protein?
UPF0751 protein BAA_A0112.
What is the protein family that this protein belongs to?
Belongs to the UPF0751 family.
Protein: ATPI_AETGR
Sequence: MNVLSCSINTLIKEGLYEISGVEVGQHFYWQIGGFQVHAQVLITSWVVIAILLGSAVLVVRNPQTIPTDGQNFFEFVLEFIRDVSKTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIQLPQGELAAPTNDINTTVALALLTSVAYFYAGLSKKGLGYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: EXOC8_DICDI
Sequence: MKKGVTYPLKIDTNLSTVSSSVNYNDIECVDIKSNGHYIVKFMYREWVGPLNLMTTQKTSIKISIDLKEQTVTCTHTDKKKTVYRWGEFPNKKETEQNKKEDNPVQYETFLSSNFNSEKYVNDLFTHKTDQQATVHLQYLENRKLGCIDHLKKDVYKNHLIFIGASKEIANSEVDMLDFRNLISDYGNVMSSLQNISISWDHYKVKKSGKIDFEPLSPATEPIQWLTTAPNELSVSIEQREFEVAVGLVEKINKIYESNPKVEIVMQTHPLKDQIENKVKILTDKLMNELRSPLLKANQIKDTISLLVRLSQNDKAKSIFLESRSHSINQAIKKIVFSGDLNRFIGELARVIFNSINSTCNDFTNSFPSYMNSGLVSWIIEELVLISDIFNRQVFILDNFYSISQAIRIIESHCEMMDQTGLSIGFYWNLLLQPHVEQLIVNYEIKIRDSMLHQLMDEKWNGVSNWDYEVKSQLNSLPSSLKNSGTPNSGGSGISNNNSNNNNNYQSPIINNNFNSGGGNKKIGLTFQQMHQDNLNNMEDIDQGRLKLTSSTIFLNTIIQKFAIDICQIITIDLIPVISQSLGSIFKDYMSYLKNEIQKEYLSDTQCLAIISDSVYIVDDLVSRIATRFEDATGEKLNNLTQLSSLLYSYFESIRDQYSTRKALELVDNSMNWEEQEYQVEEELDPFPKNFIVLSEALDRLAESIQTNVNVESVLPIASRIISEIVNIISNRFESTSNLVFGYGGLQHFILEMKYLATFAGKYPVEDSTFELINTMIRNHKEIYLNNTSDPKPLKTEEYFTSIIDNLVYQKAVYN
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 8, Exocyst complex component Exo84.
What is the protein family that this protein belongs to?
Belongs to the EXO84 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cell projection.
Protein: ATPE_STRP3
Sequence: MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAPLQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLRAEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y505_ZYMMO
Sequence: MPILAKRVLFIDAEAMIIDKPAGLPVTSVRDGSLSLENYLASLCFGFKRWPSIVHRLDRDTSGCLLLARNPKMHRRLSEAFSQGQVKKCYWAILEGVPEKNEGIIDLPLLKISSPKSGWRIVADDKGKRAVTHWEILAKNKGRSLVAFRPETGRTHQLRVHAATGLGLPIVGDPFYGSHKDENISRMMLHAHSLEIARLEKKPITAEAPLPKAFTDLGF
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase ZMO0505, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: HDGR2_HUMAN
Sequence: MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEIKFALKVDSPDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMEKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDLHDSVREGPDLDRPGSDRQERERARGDSEALDEES
What is the function of this protein?
Acts as an epigenetic regulator of myogenesis in cooperation with DPF3a (isoform 2 of DPF3/BAF45C) (PubMed:32459350).  Associates with the BAF complex via its interaction with DPF3a and HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF complex) to myogenic gene promoters (PubMed:32459350).  Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs (PubMed:26721387).  Preferentially binds to chromatin regions marked by H3K9me3, H3K27me3 and H3K36me2 (PubMed:26721387, PubMed:32459350).  Involved in cellular growth control, through the regulation of cyclin D1 expression (PubMed:25689719).
What are the official names of this protein?
Hepatoma-derived growth factor-related protein 2, HDGF-related protein 2, HRP-2, Hepatoma-derived growth factor 2, HDGF-2.
What is the protein family that this protein belongs to?
Belongs to the HDGF family.
Protein: BETA_STAAW
Sequence: MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATNPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGVTYKKNGKLHTIDAKEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGAIEVKPYAK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: MICB_HUMAN
Sequence: MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGT
What is the function of this protein?
Seems to have no role in antigen presentation.  Acts as a stress-induced self-antigen that is recognized by gamma delta T cells.  Ligand for the KLRK1/NKG2D receptor.  Binding to KLRK1 leads to cell lysis.
What are the official names of this protein?
MHC class I polypeptide-related sequence B, MIC-B.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family. MIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Binding to human cytomegalovirus glycoprotein UL16 causes sequestration in the endoplasmic reticulum.
Protein: XPF_CRIGR
Sequence: MDRGISAVRKAMAPLLEYERQLVLELLDSDGLVVCARGLGADRLLYHFLRLHCHPACLVLVLNTQPAEEEYFINQLKIEGVEHLPRRVTNEITSNSRYEVYTQGGIIFATSRILVVDFLTDRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPAMLSIQTAILDILNACLKELKCHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEKVFGQNSGWLFLDASTSMFVNARARVYRVPDVKLNKKAKMSESAEGQETKKELVLESNPKWEALSEVLKEIEAENKESEALGGPGQVLICASDDRTCCQLRDYLTAGAEAFLLRLYRKTFEKDSKAEEVWVNLRKGDGPKRTMKSDKRPKDTKNKERASTKKGAPKRKKRELTLTQVMGTAEEPPEEGAAEEDQQRQATSSPEGCGGEIQHEAFDLNLSSDSAYGILKEPLTIIHPLVGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLARGTVSTDAPADTRKAGGQEHNGTQPSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLNSGRLYSQCLAMSRYYRRPVLLIEFDAGKPFSLAPRGSFFQEMSSSDVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSETLPESDKYNPGPQDFVLKMPGINAKNCHSLMNHVKNIAELASLSQERLTSILGHAGNAKQLYDFLHTAYADVVSGGRVRK
What is the function of this protein?
Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair, and which is essential for nucleotide excision repair (NER) and interstrand cross-link (ICL) repair.
What are the official names of this protein?
DNA repair endonuclease XPF, DNA excision repair protein ERCC-4.
What is the protein family that this protein belongs to?
Belongs to the XPF family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of DNA damage.
Protein: CAIB_ECOLU
Sequence: MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKARETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNVMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOL2_ARATH
Sequence: MASNYRFAIFLTLFFATAGFSAAALVEEQPLVMKYHNGVLLKGNITVNLVWYGKFTPIQRSVIVDFIHSLNSKDVASSAAVPSVASWWKTTEKYKGGSSTLVVGKQLLLENYPLGKSLKNPYLRALSTKLNGGLRSITVVLTAKDVTVERFCMSRCGTHGSSGSNPRRAANGAAYVWVGNSETQCPGYCAWPFHQPIYGPQTPPLVAPNGDVGVDGMIINLATLLANTVTNPFNNGYYQGPPTAPLEAVSACPGIFGSGSYPGYAGRVLVDKTTGSSYNARGLAGRKYLLPAMWDPQSSTCKTLV
What is the function of this protein?
May play a role in a brassinosteroid-dependent regulation of growth and development.
What are the official names of this protein?
Protein EXORDIUM-like 2.
What is the protein family that this protein belongs to?
Belongs to the EXORDIUM family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, apoplast.
Protein: METK_SALDC
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLNTSTKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPAEQLILLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGRENFPWEKIDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_MYCLE
Sequence: MTELPTTVPGYNSAVAQTDSDAMRYRYTAELAGRIESTWQDNWARLQTFNVPNPVGSLAPPDGSVVPADKLFVQDMFPYPSGDGLHVGHPLGYIATDVYARYFRMTGHNVLHAMGFDAFGLPAEQYAMQTGTHPRILTEANVVNFRHQLGRLGLGHDSRRTFSTTDVEFYKWTQWIFLQIYNAWFDVAANKARPIAELIAEFDSGERRLVDGRDWATLSAGERADVIDNCRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYADRLLDDLDLLDWPEQVKTMQRNWIGRSSGATVLFSAILSRSDAATTEVDVEVFTTRPDTMFGVTYLVLAPEHNLVDELVATVWPDRTDPRWTYGAATPGAAVAAYRRAIVAKSDLDRQESKEKTGVFLGRYATNPATGKPVPIFVADYVLVGYGTGAVMAVPGHDPRDWDFAHKFHLPIVEVIAGSDISEAAYVGDGVLVNSGYLDGMDVATAQEAITARLESEGRGHARIEFKLRDWLFARQRYWGEPFPIIYDSDGRPHALDEAALPVELPDVPYYSPVLFDPDDADSEPSPPLAKATEWVHVELDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERLCAKENEAYWMGPRPTEHGIDDPGGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLINQGYIQAFAYTDAHGSYVPANQVFQRGDGFFCPGPDGEIEVFQEFGKIGKSLKNSVSPDEICDEYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDERTGETRVVDTAGELDTYTLRTLHRTIAGVSQDYAALRNNTATAKLIEYTNHLTKEHRGSVPRVAVEPLVLMLAPLAPHLAEELWLRLGHTTSLANGPFPQADPAYLVDDTVEYPVQVNGKIRGRIVVAADADYDTLKTVALADDKVQQFLAGATPRKVIVVAGRLISLVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_LISMF
Sequence: MKANDIRDLSTTEIQDQEKALKEELFNLRFQLATGQLENTARIREVRKAIARMKTIVRERELA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DEF90_ARATH
Sequence: MTTKMFSYVLLHSLMMFAIILSSMGSPEKYYDCKQDGCITTPPCWRKCVSMGYPKGGECRIYSYGGVCCCDLTSKPPN
What are the official names of this protein?
Defensin-like protein 90.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.