PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_PSEPG
Sequence: MKDLLNLLKNQGQVEEFDAIRIGLASPEMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVALAKVRRERMAHIELASPVAHIWFLKSLPSRIGLLMDMTLRDIERVLYFESYVVIDPGMTTLEKGQLLNDEQYFEALEEFGDDFDARMGAEAVRELLHAIDLEHEIGRLREEIPQTNSETKIKKLSKRLKLMEAFQGSGNLPEWMVLTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLSAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFGKLEMRGLATTIKAAKKMVERELPEVWDVLAEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTREAINAKGEGRVFADLQEVDRVFRAGEAALHAKIKVRINETVKDRDGSVTKNTRIVDTTVGRALLFQVVPAGLPYDVVNQPMKKKAISKLINQCYRVVGLKETVIFADQLMYTGFAYSTISGVSIGVNDFVIPDEKARIINSATDEVKEIESQYASGLVTQGEKYNKVIDLWSKANDEVSKAMMANLSKEKVIDREGKEVEQESFNSMYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLSVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEIDCGTDHGLLMTPHIEGGDVVEPLGERVLGRVIARDVFKPGTEDVIVPAGTLVDEQWVEFIELNSIDEVIVRSPINCETRYGICAKCYGRDLARGHQVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRTSAADSVQVKNGGMVRLHNLKQVERADGNLVAVSRSGELAIADEFGRERERYKLPYGAVISVKEGEKVEAGAIVAKWDPHTHPIVTELKGTVTFVGMEENITIKRQTDELTGLTNIEVLDVKDRPAAGKEIRPAIKMVDANGKDLYLPGTDVPAQYFLPANALVGVADGAQIGVGDVIARIPQETSKTRDITGGLPRVADLFEARRPKEASILAEVSGTIAFGKETKGKRRLVITPTDGSDPYEELIPKWRHLNVFEGEQVNRGEVISDGPSDPHDILRLLGVSALAKYIVNEIQDVYRLQGVKINDKHIETILRQMLRKVEISESGDSSFIKGDQMELTHVLVENERLAGEDKFISKFTRVLLGITKASLSTESFISAASFQETTRVLTEAAVTGKRDYLRGLKENVVVGRLIPAGTGLAYHSERKRRRDADKPLRVSASEVEAALTEALNSSGN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: VE4_HPV65
Sequence: MADKAQQTPPPSTLRNNNYPGPQHPPTPSLPRRALVVGGNRGNLNRPPQRPPKPRGYEYDEDDDKENQGPGQERPPAKEEEEEGEEEERPDWSLRHLLGKWESDIEQLKDKVCRDLDNYKLKLGIHP
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MRFA_DICDI
Sequence: MDGYNQQQQQQQQQQQQHQMNLGSSGGILHSPQQQQQQQQQQQQQQQQPMNGSNNQLLGISNGGFGTMLQQSASLPINIQGSNSFSTFTPLSADDSNLKKRKIKNEDGTYSEIPYSPNSLVGSNGGLDSSFLMLQQQLQDQQQQIAQFNSSVNSPSFSLNSSQVNNNNNNNNNINNNNNSNNNINNNNSNNNINNNNNNNNNNNNNINNNNINNNNNYNNNNNNNNHNHLQTTTTTTTNNGLTINANNTPSQLSSSSLYPGIIPQISITNTQSGYTPRSISPNPSPNLSPTNSPIQSPHLPTDNYLMIGSENENSDPPSPMTQYNENPPFTWTDYKSEPWYTTFNTNGDEMPVPLLNIMASKGFSYIGGQWIYCRRNHFQLDITAVYPKLFQETQYGHNGVTLSNSSSSVDPTQTPSYMLISGVKTPINGLTLTIKGIKNRADMSQQESEVELFQTNSKREKQGEHAPKPVAIQFGSLVSIQRLHFRKATLNNARRHGQPNPHQEFNQLVVSLYGRCMGQEYCIVSYVSPALIVRTATQVTPPGDLSPVHTPDYAGTSSNNGGGSNNMNCFGPTISNIDFSTMNIVSPGHSPTSPRPLSQLTSQGQTNILRLTQNHNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNSNNNSLGNINNNNSNMLTSSSLLNGRINCFNNNINNNNNNQHNNNNQHNNNNNHHNINNQHNNQNNNNNNNNNNKCHWNSGDTEKSIVYNGKVGINVENPAYALSVQGTIYASEGVYHPSDLRIKYDLKSIDSKSNLDNVNRMKLYDYKYNPQWTHMNGRDPYLDNCDRGVIAQDLQRILPNAVRTIGNKNVNGQEIENLLVIKNEALVMETIGATQELSKQMDEMKLKLITYESKLKNLKKKSKNQTILLIIFMITFLLVALYMYKPSTHHSHHRRHNFDNNDN
What is the function of this protein?
Transcription factor which acts as key regulator of pstA (prestalk-A) cells differentiation.  Essential for ecmA-specific gene expression.
What are the official names of this protein?
Myelin gene regulatory factor-like A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CHED_HALMA
Sequence: MKVYDGSQTESPEQSTPERIKVGIAEYKVTTEPAMLTTSGLGSCIGIAIYDTRNTVAGLVHVMLPSAADIDGGNHAKFADTGIQALIEAMADAGASTEAMEAKIAGGSDMLDFSENGSSIGSRNAKKVRETLDEHGVPVVGEDLGGDHGRSVKLEADTGNFIVKSANTDSITL
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: ARAA_CLAMS
Sequence: MSRITTSLDHYEVWFLTGSQNLYGEETLQQVAEQSQEIARQLEEASDIPVRVVWKPVLKDSDSIRRMALEANASDRTIGLIAWMHTFSPAKMWIQGLDALQKPFLHLHTQANVALPWSSIDMDFMNLNQAAHGDREFGYIQSRLGVVRKTVVGHVSTESVRDSIGTWMRAAAGWAAVHELKVARFGDNMRNVAVTEGDKTEAELKFGVSVNTWGVNDLVERVDAATDAEIDALVDEYERLYDIAPELQRGGERHESLRYGAAIEVGLRSFLEEGGFGAFTTSFEDLGGLRQLPGLAVQRLMAEGYGFGAEGDWKTAVLIRAAKVMGSGLPGGASLMEDYTYHLVPGEEKILGAHMLEICPTLTTGRPSLEIHPLGIGGREDPVRLVFDTDPGPAVVVAMSDMRERFRIVANVVEVVPLDEPLPNLPVARAVWKPAPDLATSAAAWLTAGAAHHTVMSTQVGVEVFEDFAEIARTELLVIDEDTTLKGFTKEVRWNQAYHRLAQGL
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: MNMA_CLONN
Sequence: MVKMSKKVAVGLSGGVDSSVAAYLLKEKGYDLIGITMKVSCDLDVSEDAKKVADKLGIPYYVIDLTEEFKNKVIDNFAEEYLQGRTPNPCAVCNKHIKFGALIQKAKELGADYIATGHYARIEEHNGRFLVLNAKDDKKDQTYMFYSLTQDVLKHILMPCGEYTKDQIREIAKKIGLEVHNKKESMDICFIPDNDHGKYIKGLECRDRIKPGNFVDKDGKILGTHKGLIYYTIGQRKGLGLSLGKPGFVIDINPERNEVVIGDEEEIFNEGLIAKEVNFIPFDSLENPMEVEAKIRYSTTKSKATIIPYDDGKIKVMFKDKQRAITKGQRVVFYIQDMLVGGGTIESIVK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CALBD
Sequence: MALPRPVQYGKVQRMSYGKVKEVLDLPYLLEIQKKSFQWFLDEGLREVLREISPIKDYSETLLLEFVDYYFDGPPKYSEQECKERDATYARPLKVKVRLINKETGEIKEQDIYMGEFPIMTETGTFIINGAERVIVSQLIRSPGCYFASSIDKQGRKIFSGTLIPNRGAWLEFETDASELLSVRLDRTRKVSLTTLLKAFGLYNQQLIFEKFGEDERLKASLEKEANKGELGNPVENALLEVYRRLRPGEPPNVENARNLLYSMFFDPRRYDLAKVGRYKFNKKLSLWKRIFNKRAAQDVVDPKTGEILVKEGELITREIATQIQDAGVNEVWVYADEERPFKVVGNNTVKLDRYVEFDVSDINIKELVYRPVLDDILNTTNDVLEIKRLIKERERELVPYCLTIDDIFAATSYFLGLKYGIGTTDDIDHLGNRRVRAVGELLQNQFRIGLARMERVIRERMNIHDIDTVTPQTLINIRPVTAAIKEFFGSSPLSQFMDQVNPLAALTNKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRMCPIETPEGPNIGLITSLATYARVNEYGFLETPYRKVDKKEARVTNEVVYLTADEEDTYKIAQATEPVDEEGRFINQRVTVRFGEEIIEVDKHEVDLIDISPKQIVSVSTSLIPFLENDDANRALMGSNMQRQAVPLLMTESPIIGTGVEYRAAVDSGVCILAKKDGVVENVSADEIVIRNNDGTKDVYHLLKFKRTNQGTCFNQRPIVRKGQEVKAGEVIADGPSTDHGELALGKNVLVAFMPWEGYNYEDAILISERLVKEDVYTSIHIEEYECEARDTKLGPEEITRDIPNVGEDAIKDLDERGIIRIGAEVKSGDILVGKVTPKGETELTAEERLLRAIFGEKARETRDTSLRVPHGEGGIVVDVKVFSRDKGDELPPGVNQLVRVYVAQKRKISVGDKMAGRHGNKGVISRILPVEDMPFLPDGTPVDIVLNPLGVPSRMNIGQILETHLGYAAKALGWKVATPVFDGAKEEDIEEALKLAGLNPTGKTILYDGRTGEPFDNEVTVGYMYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQELLTVKSDDVTGRVKTYEAIVKGENIPEPGIPESFKVLVKELQSLCLDVKLLSEDNKEIELKESVDEDEQPQGLGAFEIGGDEIEEDKEDDKEKFYEDLMNATQEDDQGEIDDIDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ANKR2_MOUSE
Sequence: MEGPEAVQRATELIEQRLAQEEETEKLRRSAPGKLSMDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPGSGRETPQPIPAQ
What is the function of this protein?
Functions as a negative regulator of myocyte differentiation.  May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 2, Skeletal muscle ankyrin repeat protein, mArpp.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Note=In the sarcoplasm of differentiated striated muscle cells, where it is cytosolic and enriched in the I band. In nucleus and PML bodies of proliferating and undifferentiated myoblasts. Associates with the euchromatin in the nucleus of myocytes upon muscle stress.
Protein: ISOC2_DANRE
Sequence: MAGIGRLSTKGSVLLLCDMQEKFRPTIFQFTNVVSNAARLLQACRILNIPQILTEQYPKGLGPTVPELGAEGLKPHTKTSFSMMTESVQSSLKSMGDPQQVILCGIEAQACIACTAYDLLERGMEVHIVADAVSSRSQTDRLFALSRLRQSGVFLNTTEGVLLQLVQDAKHPNFKEIQKLLAHPSPDTGLLAFFSSL
What are the official names of this protein?
Isochorismatase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: YJFM_ECOLI
Sequence: MARKRKSRNNSKIGHGAISRIGRPNNPFEPCRNRYAQKYLTLALMGGAAFFVLKGCSDSSDVDNDGDGTFYATVQDCIDDGNNADICARGWNNAKTAFYADVPKNMTQQNCQSKYENCYYDNVEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASRPVWRSTSGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG
What are the official names of this protein?
Uncharacterized protein YjfM.
Protein: GP_BUNYW
Sequence: MRILILLLAVTQLAVSSPVITRCFHGGQLIAERKSQTSISEFCIKDDVSMLKSEIVYTKNDTGIFGHSKVFRHWTITDWKACNPVVTAGGSINVIEVDKNLNLVTRNYVCTGDCTITVDRKNAQIIFQTDKLNHFEVTGTTISTGWFKSKASVTLDRTCEHIKVSCGKKTLQFHACFKQHMSCVRFLHRSILPGSMAISICQNIELIIITILALCIFIIMIILTKTYICYVLIPVFMPIAFAYGWAYNRSCKKCTCCGLAYHPFTNCGSYCVCGSKFETSDRMRMHRESGLCQGFKSLRVARRLCKSKGSSLIISILLSVLILSFVTPIEGTLTNYPTDQKYTLDEIADVLQAKTHEDSTKYYIILYTSLFGAGLTIIFAGVALGLTIILEVLTKINVIFCNECNMYHSKKSIKYVGDFTNKCGFCTCGLLEDPEGVVVHKAKKSCTYSYQINWVRGIMIFVAFLFVIQNTIIMVAAEEDCWKNEELKEDCVGPLIAPKDCTDKDHKTYLSEASLLATAKKITQVDAENVEILGKTMESAIRVIERQKTYHRMHLLEAVFLNKHCDYYKMFEHNSGYSQVKWRMMIKTQHFDICALQANSPFCAQCIADNSCAQGSWEFDTHMNSTYSSKVDNFKHDFSLFLRIFEAAFPGTAYVHLLTNIKEKKPYQAVSMIEKIKKKFPNNKLLIGYLDFGKYLLGLSHASTYELQQRQLDKLYQPTELTRSGGQQTSLANSVVGQATKECKKYKDVSCLSPRFGIPLEDLISCCDQPNYNIYKKPKKVYKAHDKEETWCINDQHCLVDFVPAEADTVEKLKPMKCWLVDPGKNDDVYSIAIKTCRVVDKGVCTVNSQKWNIIKCDSGPLYYSDHIPGEDTGNDIGHYCVSAGCKTDRYPINPDVVTDCVWEFTSRKSQYIGKISMQSLEDYEKALTDRLTHTLETYSFAPLENLPHIKPVYKYITAQGVENSDGIEGAFITASIPAAGGTSIGYNVRSKDGFPLLDLIVFVKSAVIKSTYNHIYDTGPTISINTKHDEHCTGQCPSNIEHEANWLTFSQERTSRWGCEEFGCLAVNTGCVFGSCQDVIRPETKVYRKAVDEVVILTVCITYPGHTFCTEINAIEPKITEEIELQFKTVDTKTLPYIVAVNNHKLYSGQINDLGTFGQMCGNVQKTNSSILGTGTPKFDYTCHGASRKDIIVRRCYNNNFDSCKLLKEETQLIFNDDHDTITVYNTNHLIGELAIKLILGDIQYKLFTETLDLQIDAKCVGCPDCFESYSCNFQIVSNIDTICSLEGPCDTFHNRISIKAMQQNYAVKLSCQKDPRPSGTFKICNREYTVVFHTVAKDDKIEINVGDQTSFIKEKDDRCKTWLCRVRDEGISVIFEPIKAFFGSYFSIFFYIIVVVVVGFLIIYIFMPMFMKLKEVLKANEKLYLQEIKQK
What is the function of this protein?
Plays a role virion budding at Golgi tubes and in subcellular location of Glycoprotein C protein.
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Glycoprotein C alone is retained in the membrane of the endoplasmic reticulum, but not transported to the Golgi. Coexpression of Glycoprotein N and Glycoprotein C results in efficient transport of Glycoprotein C to the Golgi complex, indicating that their interaction is essential for proper targeting to this organelle, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein N]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=Glycoprotein N is retained in the Golgi complex through a Golgi retention signal, which resides in the Glycoprotein N transmembrane region. SUBCELLULAR LOCATION: [Non-structural protein M]: Host Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CRJ1B_TRICY
Sequence: MSSEQVKDRAKAAIVGSLVADAATQPVHWVEDPNRLNEQLRNKSEPEFSSEWLNPRYRYDNGTFSIYGEQNYVLLKHLVENKGFNLKKYMDAYYRHFGPGTNYDQPQSRDRLPKQGPWRNEHITRALNKIQSGDQRSGTDVAECDSYAMITPLVAMYAGSGQLDSYVDHVVRVTLNNDRSVRTAQFFAKLLEHYILHGRDPEGFHKVLSHFPNDQYKRDWQTAYEERSMCNVDAVRKYGYGSSLPGNFQGALNCLTRNEDYVSSVRTTMRSGGCSAARSCGVGAWVAAQYGSQCIPSNWISRTLRGREVLEYASQIIRMMKR
What are the official names of this protein?
Crystallin J1B.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family. J1 crystallin subfamily.
Protein: RNH_CUPPJ
Sequence: MQEVIIYSDGACKGNPGRGGWGAVLVAGTNEKELFGGEANTTNNRMEMTAVIEALRALKRPCTVQVYTDSQYVQKGISEWLPGWKARGWKTADKKPVKNADLWQELDTLVQPHKITWHWVRGHNGHPGNERADALANRGVASLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYM_YEAST
Sequence: MFPRASALAKCMATVHRRGLLTSGAQSLVSKPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKYSEGYPGERYYGGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLDLPDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVAGTSAYSRLIDYARFKEISQGCGAYLMSDMAHISGLVAANVVPSPFEHSDIVTTTTHKSLRGPRGAMIFFRKGIKSVTKKGKEIPYELEKKINFSVFPGHQGGPHNHTIGAMAVALKQAMSPEFKEYQQKIVDNSKWFAQELTKMGYKLVSGGTDNHLIVIDLSGTQVDGARVETILSALNIAANKNTIPGDKSALFPSGLRIGTPAMTTRGFGREEFSQVAKYIDSAVKLAENLKTLEPTTKLDARSRLNEFKKLCNESSEVAALSGEISKWVGQYPVPGDI
What is the function of this protein?
Interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase, mitochondrial, SHMT, Glycine hydroxymethyltransferase, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DESI2_CHICK
Sequence: MANQLVILNVYDMYWMNEYTSSLGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNASELGETFKFKEAVVLGSTDFMEDDIEKIVEELGKEFKGNAYHLMHKNCNHFSSALSEILCGKEIPRWVNRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASLASSASGSRTGRHTKL
What is the function of this protein?
Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
What are the official names of this protein?
Deubiquitinase DESI2, Desumoylating isopeptidase 2, DeSI-2, PPPDE peptidase domain-containing protein 1, Protein FAM152A.
What is the protein family that this protein belongs to?
Belongs to the DeSI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BACC3
Sequence: MRKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQIPPHKQGRNITSVESRLQMLELATEAEEHFSICLEELSRKGPSYTYDTMLQLTKKYPDVQFHFIIGGDMVEYLPKWYNIEALLDLVTFVGVARPGYTLHTPYPITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: GSA_MYCA1
Sequence: MGSSDQATAHARAQAASARLFDDACAVIPGGVNSPVRAFTAVGGTPPFITAARGCRLTDADGNHYVDLVCSWGPMILGHAHPAVVEAVAKAAASGLSFGAPTPAESELAAEMIARVAPVERIRLVNSGTEATMSAVRLARGFTGRAKIVKFSGCYHGHVDALLADAGSGVATLGLPSSPGVTGATAADTIVLPYNDIDAVRQAFAEFGDQIAAVITEASPGNMGVVPPAPGFNAALRALTAEHGALLIVDEVMTGFRVSRSGWYGIDPVDADLFTFGKVMSGGLPAAAFGGRAEVMERLAPLGPVYQAGTLSGNPVAVAAGLATLRHADAAAYAALDANADRLARLLSDALTNAGVPHQIPRAGNMLSVFFTDTPVTDFASARATQTWRYPPFFHALLDAGVYPPCSAFETWFVSTALDDDAFDRIAAALPAAARAAAGADEGNS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1D2_ORYSJ
Sequence: MAITLSNVNSEAGLQKLDEYLLTRSYISGYQASKDDMTVFTSLPSAPAASYVNVTRWYDHISALLRSSGVTAEGEGVKVESTACSVSPTADQKAPAADEEDDDDVDLFGEETEEEKKAAEERAAAVKASGKKKESGKSSVLLDVKPWDDETDMAKLEEAVRNVKMEGLLWGASKLVPVGYGIKKLQIMMTIVDDLVSVDSLIEDYFYTEPANEFIQSCDIVAFNKI
What is the function of this protein?
EF-1-beta and EF-1-beta' stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-delta 2, EF-1-delta 2, Elongation factor 1B-beta 2, eEF-1B beta 2.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: SYI_SALPA
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGFDSPYVPGWDCHGLPIELKVEQEFGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGRIIKNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFRAVDQDAVKAKFGLPGVSGPVSLVIWTTTPWTLPANRAISLAPDFDYALVQIDGQAVILAKDLVESVMQRIGAAEYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGAYLPGTYPTLDGVNVFKANDIVIELLKEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDKEGLRQQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKETQELLPIERTLAAMEEVAKRVEVDGIQAWWDLDPKEILGEDADQYEKVPDTLDVWFDSGSTSYSVVDARPEFAGHAADMYLEGSDQHRGWFMSSLMISVAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFNPATDMVKPEEMVVLDRWAVGCAKTAQQEILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPIMSFTADEIWGYLLGEREKYVFTGEWYDGLFGLEENEEFNDAFWDDVRYIKDQINKELENQKANGIKSNLEAKVTLKYADDANGTIKKLKLLGEEVRFIFITSQFVISEQAGGIDDENIQYNAGNTTVQAVVTRAEGDKCPRCWHYTTDVGKVAEHADICGRCVSNIAGNGEQRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C556_AGRTA
Sequence: ADGGTHDARIALMKKIGGATGALGAIAKGEKPYDAEIVKASLTTIAETAKAFPDQFNPKDSTDAEVNPKIWDNLDDFKAKAAKLSTDAETALAQLPADQAGVGNTLKTLGGNCGACHQAYRIKKD
What is the function of this protein?
Low-spin monoheme cytochrome c.
What are the official names of this protein?
Cytochrome c-556, Cytochrome c556.
Protein: RAF1_SYNE7
Sequence: MREFTPTTLSEEERQELLGQLRRKEGRWLAWARACQTLLKNGLNPQTLFEATGFEPIQQNQITVAMQVYDSILRQDPPAHVRETYQEWGSDLLYELRELDQEQRSLCAQLALERKLDADQIREVAKATKDFCRLPKQPENFDRHPGDAVAHQCWRLAQERTDLTERSRLIARGLQFAQSAGARALIEALLLDLSGVPSRKPPMLPIYRLETEEDLPRLLPFAGTLPLSSSQIEAIAAVEAEGPFGLVSSPQGQQWLALPGWQAILTAEDPIACLEQIDRLPNAPEGPTEAVVLVVDRADRDWDADHFFLVEQAEGARIQWSPSAIAAPILGRLVLILRPKRVLDEAAIATPWQFEE
What is the function of this protein?
It has been suggested that Raf1 and RbcX are partially functionally redundant (Probable).  Other evidence suggests they are antagonistic in mediating RuBisCO assembly (PubMed:32636267).
What are the official names of this protein?
RuBisCO accumulation factor 1.
What is the protein family that this protein belongs to?
Belongs to the RAF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDPJ_EMENI
Sequence: MSFGTLYTHNPTPRSTTLIALAKLHNLDVKIIHAEKKNKEAFEELCRYNPLGQVPTFVGADGFVLSECIPLTLYCNDERSSLRILQWMSFANSDLFPAVGGVFLPRIGQRQIIQQDDGDSLRAMLQRCKYLDEHLKRSRYLVGESITIADFFAASLLMGAFAAFRRSMQERFGALCSWYDGVLEIGWFKKVAGGVPDLGLELEIPEDIKW
What is the function of this protein?
Glutathione S-transferase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative (PubMed:20139316, PubMed:21351751, PubMed:22730213).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG (PubMed:20139316).  The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG (PubMed:20139316).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (PubMed:20139316).  The next step is performed by the anthrone oxygenase mdpH that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving mdpB, mdpC mdpJ, mdpK and mdpL (PubMed:20139316, PubMed:21351751).  These enzymes with xptA, xptB and xptC are also proposed to be involved in the synthesis of shamixanthone from emodin (PubMed:22730213).  Especially, direct reduction of emodin by the short chain dehydrogenase mdpC followed by dehydration catalyzed by the scytalone dehydratase-like protein mdpB gives loss of oxygen and formation of chrysophanol intermediate in two simple steps (PubMed:22730213).
What are the official names of this protein?
Glutathione S-transferase mdpJ, Monodictyphenone synthesis protein J.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: SMAL1_XENLA
Sequence: MSVCLTEEQKRKIEENRQRALARRAERLAAQQNTLKQTNNSHSTLFNIQKSTVEQGALFSGQRTNVTAACMAPLQQGSNNKYAFQKTSSGGSAASSLPGTAENKPQAGGNGPCDYKVPADPAQDFTSSKNLTGKYVAPKAHCVSSVPSFNDTPNPRQLNPACTTQEQEKPKNSSYSYSRPDSDTACDKFTAGPGPGPIRNTTAISKFYGANPGIKPALPVSNKTVSEVRDRGVTGSSVEAVPVKKASSSTRGRCVKHMEGRFRVEVGYSAELIALFKTIPSKAYDPATKMWNFGLEDYASLMSEVQRVQSVELKALEGMEGVQIAPPPTSGSGTNINALLAMCNNWQRPNATLRGRCILISRSRFEMEIGYHTEIIGLFKQMNTRNYDTKTRKWSFMLEDYQKLMESVRNIQQVEVEPLPRPVLQAFAPQFEKTTISLAEIEDVDLSHVDSKLIGNLMPFQRDGVNFAISREGRLLLADDMGLGKTIQAICIAAYYRKEWPLLVVAPSSVRFTWAEAFHRWLPSLNPESVNVIVTGRDSQSANLINIISFDLLGKMDKQIAANFKVIIIDESHFLKNVKTARCKAAMPLLKSAKRVMLLSGTPAMSRPAELYTQIAAVRPTFFPRFHDFGIRYCDAKQMPWGWDYSGSSNLNELKLLLEESIMIRRLKSEVLSQLPAKQRKMVVVAPEGITAKTKAALAAAAKEMAKGFKSKVQEKEALLLFYNRTAEAKIRSVLEYIIDLLESGREKFLVFAHHKLVLDNICEELGKKEVPYIRIDGNTSSADRQSLCHKFQFSEKSCVAVLSITAANMGLTLSSADLVVFAELFWNPGVLIQAEDRVHRIGQTSSVNIHYLVAKGTADDYLWPMIQEKIKVLGQAGLSEANFSETTESTDYFYKDPKQKTIYDLFQRSFSEQGAENDSDEALLLEACEEVDLGESTCGPTDYSGNACKRRKIDDYFAL
What is the function of this protein?
ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA.  Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA).  Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, HepA-related protein, Sucrose nonfermenting protein 2-like 1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus.