PharMolix/UniProtQA huggingface dataset:
Protein: PHK_THEVB
Sequence: MVSSPPRPTALTDDIHAFGPARATIQGQPLSDSEVEAMDAFFRACNYLAVGMIYLLDNPLLKEPLKPEHIKKRLLGHWGSSPGLAFCYLHLNRIIKKYQQEVIFLAGPGHGAPGVLAPVYLEGSYSEIYPNISEDAAGLKKFFKQFSFPGGIGSHCTPETPGSIHEGGELGYVLSHACGAAFDNPDLIVAAVVGDGEAETAPLATSWHINKFLNPARDGAVLPILNLNGYKINNPTILARIPHQDLENYFRGLGYDPCFVEGSDRPSMHQAMAATLDYCVTRIKEIQRTAREEGLTTLPRWPMIVLRTPKGWTGPAEVNGHKVEGSWRAHQVPLADVHTNPENLQLLENWLRSYRPEELFDHNGTFRPDLKALAPTGNYRMGMNPHANGGLLRKDLKMPNFREYGITFDKPGQIEVENTRPLGVFLRDVMRNNPRNFRIFGPDETTSNKLNAVYEASKKFWIAESFDEDADGGELSPEGRVIEMLSEHTLEGMLEGYLLTGRHGFFSTYEAFVHVIDSMFNQHAKWLSICNELSWRADVSSLNLLITSTVWRQDHNGFTHQDPGFLDIVCNKSAKVTRIYLPPDVNSLLSVADHCLRSKNYVNVIVSDKQLHLQYLTMDQAIIHCTKGVGIWDWASNDQGYEPDLVMASAGDIPTQEALAAIALLRQEFPELKIRYINVVDLFKLQPETEHPHGLSDRDFDSLFTLDRPIIFNFHGYPWLIHRLAYRRHNHRNLHVRGYKEKGNINTPLELAINNEIDRFSLAIDAIDRLPELQVAGAHAKEKFRNMQIAARNYAYEYGVDKPEFSHWTWPF
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: ECTA_VIBCH
Sequence: MIYPQIMHKPALPWVFRRPTQEDGLSIHELIAQCAPLDQNSAYCNFLQSSHFQTTCLMAEQQELLVGFVSAYRKPEQQNELFIWQVAVHPSARGKGLAYQMLKHLLAREDLADITVLETTITRSNQASWRLFQKLDREQGEQGSVSTFLDETCHFEGEHDTEYLYRIPLQSSN
What is the function of this protein?
Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.
What are the official names of this protein?
L-2,4-diaminobutyric acid acetyltransferase, DABA acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. EctA subfamily.
Protein: RL20_MICLC
Sequence: MARVKRAVNAHKKRRTMLERASGYRGQRSRLYRKAKEQMLHSFTYNYQHRHKRKGDFRRLWITRINAAARANGMTYNRFMQGLKLAGVEVDRRMLAEIAVSDAATFAVLVKTAREALPADVNAPAASR
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ADH1_CANAX
Sequence: MSEQIPKTQKAVVFDTNGGQLVYKDYPVPTPKPNELLIHVKYSGVCHTDLHARKGDWPLATKLPLVGGHEGAGVVVGMGENVKGWKIGDFAGIKWLNGSCMSCEFCQQGAEPNCGEADLSGYTHDGSFEQYATADAVQAAKIPAGTDLANVAPILCAGVTVYKALKTADLAAGQWVAISGAGGGLGSLAVQYARAMGLRVVAIDGGDEKGEFVKSLGAEAYVDFTKDKDIVEAVKKATDGGPHGAINVSVSEKAIDQSVEYVRPLGKVVLVGLPAHAKVTAPVFDAVVKSIEIKGSYVGNRKDTAEAIDFFSRGLIKCPIKIVGLSDLPEVFKLMEEGKILGRYVLDTSK
What are the official names of this protein?
Alcohol dehydrogenase 1, 40 kDa allergen, Allergen Can a 1, Allergen Can a I.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP44_MOUSE
Sequence: MLRSKTFLKKTRAGGVVKIVREHYLRDDIGCGAPACSACGGAHAGPALELQPRDQASSLCPWPHYLLPDTNVLLHQIDVLEHPAIRNVIVLQTVMQEVRNRSAPIYKRIRDVTNNQEKHFYTFTNEHHKETYIEQEQGENANDRNDRAIRVAAKWYNEHLKRVAADSQLQVILITNDRKNKEKAVQEGIPAFTCEEYVKSLTANPELIDRLAYLSDEMNEIESGKIIFSEHLPLSKLQQGIKSGSYLQGTFRASRENYLEATVWIHGDKEEEKEILIQGIKHLNRAVHEDIVAVELLPRSQWVAPSSVVLDDEGQNEDDVEKDEERELLLKTAVSEKMLRPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASALEGRRIIVAIDGWPRNSRYPNGHFVKNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPRMPWSITEEDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDDITTSLRGLNQLAKILKKGRIEKGALTLSSPEIRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYDILVKAAKSKNLQIKTDTAKSLADSLDRAESPDFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLSDICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLAYDDEIPSLRIEGTVFHVFDKVKVKITLDSSNLQHQKIRMALVEPQIPGINIPPNVADKALTAPGGKKRKLEK
What is the function of this protein?
Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  DIS3 has both 3'-5' exonuclease and endonuclease activities.
What are the official names of this protein?
Exosome complex exonuclease RRP44, Protein DIS3 homolog, Ribosomal RNA-processing protein 44.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus. Note=Predominantly located in the nucleus. According to, found in the nucleolus. According to, excluded from nucleolus supporting the existence of a nucleolar RNA exosome complex devoid of DIS3.
Protein: KDUI_ECOLU
Sequence: MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: SYFA_SHEAM
Sequence: MQQLTEIVEQALAAIEQATDLKVLDDIRVDYLGKKGQITDLMKLMGTLSAEEKPKFGQAVNDAKQSVQAKLGEQMELFKARELEAKLAAEQIDVTLPGRTLDNGGLHPVTRTIERIESFFGELGFTVKQGPEIEDDFHNFDALNISEHHPARADHDTFYFNPKVMLRTQTSGVQIRTMETEKPPLRIISPGRVYRNDYDMTHTPMFHQVEGLLVDENVNFAELKGILHDFLRNFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT2_PANTR
Sequence: MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSAKDSKGIFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANERFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRCQDCLEALDVHTCKAPKNADWTTPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity).  Functions as upstream regulator of FGF10 expression.  Plays an important role in embryonic lung development.  May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: RSMB_SALPK
Sequence: MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYLIMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQWQRIIEANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAVFLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPAQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDTVWPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSETGTPDQPGQQNLPGGEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_RHOPB
Sequence: MAEMKTADIRAMSPDQKDDAVAELKKERFNLRFQRATGQLENTSRLREARRDIARIKTIAAQQRDAKK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GSG1_RAT
Sequence: MEFQKGPSDQRTFVSAILNMLSLGLSTASLLSSEWFVGAQKVPKPLCGQSLAAKCFDMPMSLDGGITNASAQEVVQYTWEAGDDRFSFLTFRSGMWLSCEETVEEPGEKCRRFIELTPPAQREVLWLSLGAQTAYIGLQFISFLLLLTDLLLTSNPGCGLKLSAFAAVSLVLSGLLGMVAHMLYLQVFQATANLGPEDWRPHSWNYGWAFYTAWVSFTCCMVSAVTTFNTYTRMVLEFKCRHGTSFNTNPSCRAQHHRCFLPPLTCAVHAGEPSTSCHQHPSHPIRSVSESIDLYSAAALQDKKFQQENSQELKEATESSVEEQC
What is the function of this protein?
May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum.
What are the official names of this protein?
Germ cell-specific gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the GSG1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with PAPOLB in the endoplasmic reticulum.
Protein: Y719_HAEIN
Sequence: MMTQIIHTEKAPAAIGPYVQAVDLGNLVLTSGQIPVNPATGEVPADIVAQARQSLENVKAIIEKAGLTAADIVKTTVFVKDLNDFAAVNAEYERFFKENNHPNFPARSCVEVARLPKDVGLEIEAIAVRK
What are the official names of this protein?
RutC family protein HI_0719.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: ATPB_CUSRE
Sequence: MRINPPTYGSEISSIEKKNRGHIVQIIGPVLDVAFPPGKMPNIYNALIVKGRDTEQMNVTCEVQQLLGNNRVRAVAMNDTDGLMRGMEVIDTGTPITVPVGGSTLGRIFNVLGEPVDNLGPVDTNTTFTIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNITESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSMMLQPRLVGEEHYETAQKVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIIGFTLILSGELDSLPEQAFYLVGNINEATEKAMNLKT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, plastid, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid thylakoid membrane; Peripheral membrane protein.
Protein: CHLN_THEVB
Sequence: MTVTAPNALNFECETGNYHTFCPISCVAWLYQKIEDSFFLVIGTKTCGYFLQNAMGVMIFAEPRYAMAELEEGDISAQLNDYEELKRLCLEIKRDRNPSVIVWIGTCTTEIIKMDLEGLAPKLEAEIGIPIVVARANGLDYAFTQGEDTVLAAMAARCPTSTAISDPEERNPIQRLLNFGKKKEEVQAQSSQYHPHPPLVLFGSLPDPVVTQLTLELKKQGIKVSGWLPAKRYTELPVIDEGYYVAGVNPFLSRTATTLIRRRKCQLITAPFPIGPDGTRTWIEQICATFGIQPQGLAEREAETWQKLSDYLELVRGKSVFFMGDNLLEISLARFLIRCGMRVLEIGIPYMDKRYQAAELALLSQTCAEMGHPLPTIVEKPDNYNQLQRIKALQPDLVITGMAHANPLEARGISTKWSVEFTFAQIHGFGNARDILELVTRPLRRNQALAGLGWQKLVAH
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: SFSA_ACTSZ
Sequence: MQLPLLQPAIFIRRYKRFMADVELPNGEILTIHCANTGAMTGCAEKGDTVWYSDSKSTTRKYPCSWELTQLSNGSLVCINTHRSNQLVHEALQNKVIKELADYSEIYPEVKYGEENSRIDFLLKGEGLPDCYVEVKSITLVKNSIGMFPDAVTTRGQKHVRELLAMKKQGHRAVVLFAGLHNGFDCFKIAEHIDPEYDRLLKDAMRQGVEAYAYAGAFEKTQEIPTALSLTGKVPFIE
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RECR_BACAA
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAVRLAFFVLDMKEDDVLGFAKALVNAKRDLAYCSVCGHITDRDPCYICNDSHRDQSVVCVVQEPKDVIAMEKMKEYQGVYHVLRGAISPMGGIGPEDINIPQLLKRLHDETVQEVILATNPNIEGEATAMYISRLLKPTGIKVTRIAHGLPVGGDLEYADEVTLSKALEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: FMT_ALKMQ
Sequence: MRVIYMGTPEFAVAPLHSLIGNQYDVVAVFTQPDRPKGRGKKLQSTPVKELALAHGLMLYQPIKLRESSVVEIIKSLEPDVIVVVAYGQILSKEILEIPTYGCINVHASLLPKYRGAAPIHRAIIDGEKKTGVTTMYMDVGLDTGDMLLKKEVLIGADETAGELRDRLMALGADTLIKTLNQVQRGTLVGEKQNDLESSYAAMLDKGLGQINWNQSAEAIRNLIRGTIPWPMAYTTYLGNRVKIWKSRIEESEVSGKPGEILKVEKSGIFVKTGQGTLVIERIQFSGKKPLDVREYLAGNTIEKGVLLGEEDGN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SYL_BACC4
Sequence: MSFNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEIIDGKSERGGHPVERRPMRQWMLKITAYGDRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKFTVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKTGVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVKGGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEATSAGNQKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGKKGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPFQQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAYKAETLPREYVEGFVKMIAPVAPHIGEELWSKLGYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLTMSKDASKEEMEQLALEAIQDQIEGKTVRKVVVVPGKLVNVVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIC1_PHYIN
Sequence: MPITCGDIPRLICSVIIPPVGVFFQVGCTKDLAINCLLTVLGYIPGVIHAVYILIKE
What are the official names of this protein?
Protein Ric1.
What is the protein family that this protein belongs to?
Belongs to the UPF0057 (PMP3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DCTA_PSEP1
Sequence: MTTRQPLYKSLYVQVLVAITIGILLGHYYPETGVALKPLGDGFVKLIKMVIAPIIFCTVVSGIAGMQSMKSVGKTGGYALLYFEIVSTIALIIGLVVVNVVKPGAGMHIDVSTLNASSVAAYAAAGAQQTTVGFLLNVIPNTVVGAFANGDILQVLMFSVLFGFALHRLGSYGKPVLDMIDRFAHVMFNIINMIMKLAPIGAFGAMAFTIGQYGVGSLVQLGYLMACFYITCLLFVLVVLGGICRAHGFSVIKLIRYIREELLIVLGTSSSESALPRMLAKMERLGAKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATDTTMDITHQITLLLVLLVASKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNAVATVVVAKWVKEMDNDKLASELASGGAPLVDTRPTDDLGVAEGPAR
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SHUT_ADE41
Sequence: MEEDLIQPQPDSETLTSPTSEVGAVELVEHEDDERVEQDPGYVTPPKDGKESVPVSPLTEADYLGGEDDVLLKHVLRQSTIVQEAFKDYSGFPLTVEELSRTYEANLFSPRVPPKKQANGTCEPNPRLNFYPVFAVPEALATYHIFFKNQRIPLSCRANRTQGDRILHLKAGAHIPEIVSLEEVPKIFEGLGKDEKRAANALQKSETENQNVLVELDGDNARLAVLKRTIEVSHFAYPALNLPPKVMRSVMDHLLIKRVEPLDSDQPEQNSEDGQPVVSDDDLARWLDSHDPTTLQERRKMMMAVILVTVELECLQRFFANPQTLRKIEESLHYAFRHGYVRQACKISNVELSNLVSYMGILHENRLGQNVLHCTLQGEARRDYVRDCIYLFLILTWQTAMGVWQQCLEERNLRELEKLLVRNRRELWTAFSERTAACQLADLIFPERLMQTLQNGLPDFVSQSILQNFRSFILERSGILPAMSCALPSDFVPLCYRECPPPLWSHCYLLRLANYLAHHSDLMENSSGEGLLECHCRCNLCTPHRSLVCNTELLSETQVIGTFEIQGPERQEGASNLKLTPALWTSAYLRKFIPEDYHAHQIKFYEDQSRPPKAPLTACVITQSQILAQLQAIQQARQEFLLKKGHGVYLDPQTGEELNTPSPSAAASCRPQKHAAQREQASHCGSAVPKATETARAVGRGGGILGRQPGRGSFRRGGNGELGKSRRGAGGQTPQGRGGRNHRQRRGTVFQRTRSEPASDGESRTVPAAARLVESQP
What is the function of this protein?
Protein that inhibits host translation while promoting late viral translation by ribosome shunting.  Blocks host cap-dependent translation by binding to eIF4G, displacing MKNK1 from cap initiation complexes and preventing EIF4E phosphorylation.  Binds to the tripartite leader sequence of viral late mRNAs and recruits host eIF4G, PABPC1/poly-A binding protein and 40S ribosomes subunits on viral mRNAs, allowing ribosome shunting and efficient translation of late viral mRNAs even though conventional translation via ribosome scanning from the cap has been shut off in the host cell.  During assembly, acts as a chaperone protein that helps hexon proteins assembly into trimers.
What are the official names of this protein?
Shutoff protein, 100 kDa protein, p100K, 100K-chaperone protein, L4-100K, Shutoff protein 100K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae shutoff protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PLM1_PLAFX
Sequence: MALSIKEDFSSAFAKNESAVNSSTFNNNMKTWKIQKRFQILYVFFFLLITGALFYYLIDNVLFPKNKKINEIMNTSKHVIIGFSIENSHDRIMKTVKQHRLKNYIKESLKFFKTGLTQKPHLGNAGDSVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCNTIGCKTKNLYDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLSFPYKFIEVTDTNGFEPAYTLGQFDGIVGLGWKDLSIGSVDPVVVELKNQNKIEQAVFTFYLPFDDKHKGYLTIGGIEDRFYEGQLTYEKLNHDLYWQVDLDLHFGNLTVEKATAIVDSGTSSITAPTEFLNKFFEGLDVVKIPFLPLYITTCNNPKLPTLEFRSATNVYTLEPEYYLQQIFDFGISLCMVSIIPVDLNKNTFILGDPFMRKYFTVFDYDNHTVGFALAKKKL
What is the function of this protein?
During the asexual blood stage, catalyzes the initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation; specifically cleaves between Phe-33 and Leu-34 of Hb alpha-chain (PubMed:8313875, PubMed:2007860, PubMed:8844673).  Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).
What are the official names of this protein?
Plasmepsin I, Aspartic hemoglobinase I, Plasmepsin 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein. Vacuole lumen. Vacuole membrane. Note=At the beginning of the asexual blood stage, the transmembrane zymogen is transported to the cytostome, an endocytic structure spanning the parasite cell membrane and the parasitophorous vacuole membrane where host proteins such as hemoglobin are endocytosed (PubMed:9169469). Following endocytosis, localizes to the cytostome vacuole membrane to be then delivered to the digestive (or food) vacuole where it is cleaved into the soluble and active enzyme (PubMed:9169469). In trophozoites, localizes to the digestive vacuole, an acidic vacuole where host hemoglobin is digested (PubMed:8313875, PubMed:9169469).
Protein: MC69_MAGO7
Sequence: MKAAFVLALCASLASAWVVITPITKEMVVDRSPDDCFFGVVTPQGCGPLRGPAK
What is the function of this protein?
Secreted protein required for appressorial penetration of intact host epidermal cells and for pathogenicity.
What are the official names of this protein?
Secreted virulence factor MC69.
What is the protein family that this protein belongs to?
Belongs to the MC69 virulence factor family.
What are the subcellular locations of this protein?
Secreted. Note=Accumulates in an interfacial structure named the biotrophic interfacial complex (BIC) but is not translocated into rice cells.
Protein: PSB28_CYAM1
Sequence: MASIQFIQGVDEDIIPTVRLTRSRDGQTGTAVFRFVQPKLLQQQGEITGMYMIDEEGEIVTREVQAKFVNGQPQIIEALYVMKNAQAWERFMRFMNRYAEAKGLSFQRS
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RS4_BACLD
Sequence: MARYTGPSWKLSRRLGISLSGTGKELEKRPYAPGPHGPGQRKKLSEYGLQLQEKQKLRHMYGVNERQFRNLFDKAAKMAGKHGENFMILLESRLDNIVYRLGLARTRRQARQLVNHGHVLVDGSRVDIPSYQVKPGQTISLREKSQNLSVVKEAVEVNNFVPEYLTFDAEKLEGSLTRLPERSELPAEINEALIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: LPXC_XANOP
Sequence: MTQQRTLKNTIRATGVGLHSGDKVYMTLRPAPVDHGVVFRRVDLEPIVEVPADAELVTETTLCTGLSCNGAKIQTVEHLMSALAGLGVDNVIVELSSAELPIMDGSSGPFVFLLQSAGIVEQSKPKRFIRIKQTVEVRDGDKVARFEPYEGYKLGFTIEFNHPMIPAKQSRQEIDFSTSAYVTEISRARTFGFMRDLEYMRERNLGLGGSMDNAIVLDEFRVLNEDGLRYTNEFVRHKILDAIGDLYLAGGAILGAYEGFKSGHALNNKLVRALLADQAAWEWVSFPEGTEQPPVTYASPVYA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: DAL80_YEAST
Sequence: MVLSDSLKLPSPTLSAAAGVDDCDGEDHPTCQNCFTVKTPLWRRDEHGTVLCNACGLFLKLHGEPRPISLKTDTIKSRNRKKLNNNNVNTNANTHSNDPNKIFKRKKRLLTTGGGSLPTNNPKVSILEKFMVSGSIKPLLKPKETVPNTKECSTQRGKFSLDPCEPSGKNYLYQINGSDIYTSNIELTRLPNLSTLLEPSPFSDSAVPEIELTWKLHNEEEVIKLKTKISELELVTDLYKKHIFQLNEKCKQLEVELHSRASVQSHPQH
What is the function of this protein?
Negative regulator of multiple nitrogen catabolic genes including the allantoin pathway genes.
What are the official names of this protein?
Nitrogen regulatory protein DAL80, Regulatory protein UGA43.
What are the subcellular locations of this protein?
Nucleus.
Protein: C1T9B_HUMAN
Sequence: MRIWWLLLAIEICTGNINSQDTCRQGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKVEAKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGPTGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGKIGETLVLPKSAFTVGLTVLSKFPSSDVPIKFDKILYNEFNHYDTAVGKFTCHIAGVYYFTYHITVFSRNVQVSLVKNGVKILHTRDAYVSSEDQASGSIVLQLKLGDEMWLQVTGGERFNGLFADEDDDTTFTGFLLFSSQ
What is the function of this protein?
Probable adipokine.  Activates AMPK, AKT, and p44/42 MAPK signaling pathways.
What are the official names of this protein?
Complement C1q and tumor necrosis factor-related protein 9B, C1q/TNF-related protein 9B, CTRP9B, Complement C1q and tumor necrosis factor-related protein 9-like.