PharMolix/UniProtQA huggingface dataset:
Protein: ARRS_RAT
Sequence: MAACVKTNKSHVIFKKVSRDKSVTIYLGKRDYIDHVSQVEPVDGVVLVDPELVKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLYFSRVQVYPPVGAMSAPTQLQLSLLKKLGDNTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEVKAFATDITDAEEDKIPKKSSVRLLIRKVQHAPPEMGPQPCAEASWQFFMSDKPLHLSVSLSKEIYFHGEPIPVTVTVTNNTEKVVKKIKVSVEQIANVVLYSSDYYVKPVASEETQEKVQPNSTLTKTLVLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVMGILVSYHIKVKLTVSGFLGELTSSEVATEVPFRLMHPQPEDPAKESVQDENLVFEEFARQNLKDTGENTEGKKDEDAGQDE
What is the function of this protein?
Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO.  May play a role in preventing light-dependent degeneration of retinal photoreceptor cells.
What are the official names of this protein?
S-arrestin, 48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment. Membrane; Peripheral membrane protein. Note=Highly expressed in photoreceptor outer segments in light-exposed retina. Evenly distributed throughout rod photoreceptor cells in dark-adapted retina (By similarity). Predominantly dectected at the proximal region of photoreceptor outer segments, near disk membranes.
Protein: RL36_PSET1
Sequence: MKVLSSLKSAKQRAGCQVVKRKGRVFVICKENPRFKAVQGMKKK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RLMD_VESOH
Sequence: MRRRRKLEHKTYKLNIESFSHEGRGIAHFEDKIIFVSDALPGELVIANRTFSCAKFEEADAKEILKPADNRMKPKCDVFGICGGCSFQNLSSEDQIQIKSRWLKKVFARQAKVEPETWLKSLQFQSWGYRRKARLGIRYVAKKDKVLIGFRERKSSFITNMSRCEVLHPSIGEHLEVLANCIERLSIKSSIPQFEVVISESGIALILRHLESLSVKDEKILADCAQELNITFYTQSGGLDSVKPLDEPTILTYSHSNYNIIMEFLPTDFVQVNFKLNQQMVSLAVELLELNESDKVIDLFCGLGNFTLPIARYAKYVVGIEGDLGLVERAKYNAEKNSINNVDFYRSDLCKEVVGFEWFKGKTYNKALIDPSRSGAIEIVELLPKLGVTRLVYVSCNPATLARDTLKLIKLGFTLETAGVIDMFPQTSHVESIALFVKR
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: TX106_LYCSI
Sequence: MMKVLVVFALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELMVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1e, Toxin-like structure LSTX-A6.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB_ACIBS
Sequence: MISLSDLRKFKAEGRKFSCLTCYDASMAKAMELAEIDTILIGDSLGMAIQGRDSTLPVTVEDMAYHTAAVRRGNQHALIMTDLPFMSYATLKDALQNAKTVMQAGAQMIKIEGGAWLSETVQVLTRNGVPVCVHLGLTPQSVHVFGGYKLQARTREAADQLIADCTAVVEAGAAVLLLECVPAQLGQEIAELFPNTPVIGIGAGNATDGQVLVVQDMLGLTFGRVARFVRNFMKEQSGETAILDAFKAFHAAVQDQSFPAKEHTFQVEL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THI6_YEAST
Sequence: MVFTKEEVDYSLYLVTDSTMLPPGTTLCSQVEAGLKNGVTLVQIREKDIETKNFVAEALEVQKICKKYNVPLIINDRIDVAMAIDADGVHVGQDDMPIPMVRKLLGPSKILGWSVGKPSEVETLAKWGPDMVDYIGVGTLFPTSTKKNPKKSPMGPQGAIAILDALEEFKATWCRTVGIGGLHPDNIQRVLCQCVASNGKRSLDGISLVSDIMAAPDACAATKRLRGLLDATRYQFVECELNNTFPTTTSIQNVISQVSNNRPLVQHITNKVHQNFGANVTLALGSSPIMSEIESEVSELARIPNASLLLNTGSVAPIEMLKAAINAYNEVNRPITFDPVGYSATETRLCLNNTLLTYGQFACIKGNCSEILSLAKLNNHKMKGVDSSSGKTNIDTLVRATQIVAFQYRTVAVCTGEFDCVADGTFGGEYKLSSGTEGITAEDLPCVIIEDGPIPIMGDITASGCSLGSTIASFIGGLDSTGKLFDAVVGAVLLYKSAGKLASTRCQGSGSFHVELIDALYQLFHENKPEKWSASLKKFK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine biosynthetic bifunctional enzyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Thz kinase family.
Protein: PSB2_SULTO
Sequence: METNNKLKILKTGTTTVGIKVKDGVVLAADRRASAGMYVAHKYVRKVLYVAPNIGITTAGSVADLQFIYDLLKNIYHYNLITGMRPITIKALATYLANMLSFSKYLPYIVQILIGGVDEQPRLYNLDYVGDITEEDYTATGSGSVEAIGVIEDEYRPDMTLDEAADLARRAIFSSIKRDPYTGTGVIVSKITKNGHEEKEYYPQRKI
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S40A1_ORYSJ
Sequence: MASDGHLAAPLLDGGGGVDDAALLRRLYVGHFLARWGARMWEFSVGLYMIRIWPGSLLLTAVYGVVEASAVAALGPIVGAVVDRLAYLQVLRLWLLLQGASFVAAGVSVTALLVYGARLAAAGFPAFVALVVVTNVSGALAALSTLAGTILIEREWVVVIAGGQPAAVLTGINSVIRRIDLSCKLLAPVLSGFFISFVSMEASAAALAAWNLAAVWVQYWLFVSVYAGFPALSETSQISRRRADDDEAAAAAQPQKVERLWMTMLPCWESWAVYARQEVVLPGVALAFLYFTVLSFGTLMTATLDWEGIPAYVISLARGVSAAVGIAATWVYPAAHARVSTLRAGLWSIWAQWCCLLVCVASVWAGGAAPLASAWMLMGGVAASRLGLWMFDLAVMQLMQDGVPESDRCVVGGVQNSLQSMFDLLTYVMGIIVSDPRDFGELIVLSFFLVTCAAAMYTMHVYRVRKHLFHLDRILPKMNWIKAS
What is the function of this protein?
May be involved in iron transport and iron homeostasis.
What are the official names of this protein?
Solute carrier family 40 member 1.
What is the protein family that this protein belongs to?
Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPRM_HUMAN
Sequence: MNPALGNQTDVAGLFLANSSEALERAVRCCTQASVVTDDGFAEGGPDERSLYIMRVVQIAVMCVLSLTVVFGIFFLGCNLLIKSEGMINFLVKDRRPSKEVEAVVVGPY
What is the function of this protein?
May be involved in the regulation of p53-dependent G2 arrest of the cell cycle.  Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity).
What are the official names of this protein?
Protein reprimo.
What is the protein family that this protein belongs to?
Belongs to the reprimo family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Single-pass membrane protein.
Protein: CLPP_BURO1
Sequence: MITRAELLDMLASNAPQGFEAQALGLVPIVVETSGRGERSYDIYSRLLKERLVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFIKPDVSTLCMGLAASMGAFLLASGAKGKRFALPNSRVMIHQPLGGARGQASDIEIQAREILYLKERLNNLLAQHTGQDVERIARDTDRDNFMSSEDAKAYGLIDQVLLKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
Protein: HIS7_BURO0
Sequence: MRVAEVVRNTSETQIRVKLDLDGTGQQKLATGVPFLDHMLDQIARHGLVDLEVEAHGDTHIDDHHTVEDVGITLGQAVAKAIGDRKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGINAHHQLETVFKAFGRALRAAVELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
Protein: ISK6_RAT
Sequence: MKVAGVFLLLSLALLCFFSGEFSQGGQDKRGWITRSEGRFPGKGVLRHRLFQINCGEFRDPKVFCTRESDPLCGSDGQTYGNKCAFCKALEKSSGKINLKHRGKC
What is the function of this protein?
Serine protease inhibitor selective for kallikreins.  Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14.  Doesn't inhibit KLK8.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 6.
What are the subcellular locations of this protein?
Secreted.
Protein: NFS1_CANMA
Sequence: MYKTVLKNSGRIQRNFIFRNVSSTLQRSLATSASTSSSTTTSNAETGELHVSTPLDSPSVHPPDGSSISLKSATRDASLFGTRPIYLDVQATTPVDPRVLDKMLEFYTGLYGNPHSSTHAYGWETDKEVEKARGYIADVINADPKEIIFTSGATETNNMAIKGVPRFYKKTKKHIITTQTEHKCVLDSARHMQDEGFDITYLPVNSEGLINLDDLKKAIRKDTVLVSVMAVNNEIGVIQPLKEIGQICRENKIFFHTDAAQAYGKIPIDVNEMNIDLLSISSHKIYGPKGIGACYVRRRPRVRLDPIITGGGQERGLRSGTLAPPLVAGFGEAARLMKQESAFDKKHIEKLSTKLKNGLLSIPSTQFNGCNNPTYQYPGCVNVSFAYIEGESLLMALKDIALSSGSACTSASLEPSYVLHALGADDALAHSSIRFGIGRFTTEAEVDYVIQAINERVDFLRKMSPLWEMVQGGIDLNSIEWSGH
What is the function of this protein?
Catalyzes the removal of elemental sulfur from cysteine to produce alanine.  It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters.  Plays a role in both tRNA-processing and mitochondrial metabolism.  Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.
What are the official names of this protein?
Cysteine desulfurase, mitochondrial, tRNA-splicing protein SPL1.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYH_NATTJ
Sequence: MLTKAPRGTKDILPQESSKWHALEETAKKISNLYGFNEVRFPIFEHTELFTRSVGETSDIVSKEMYTFTDRGDRSLTLRPEGTAPAARLYVEHKLFNEPQPVKYYYIGPMFRYDRPQAGRYRQFHQFGVEVFGSLEPETDVEVMKLLLDYFEALGLSGLELKLNSVGCKECRQKYLNELSNYFEGKIDHICQDCYQRYQTNPMRVLDCKKKSCREAIGEDVPLIVNYLCQDCATHFDKVKEILTSLNLPYQIDPHLVRGLDYYTKTAFEVVMPSLGAQDALGGGGRYDYLVEECGGPPTPGVGFAVGLERILLALEQKEINLDQEEKLDFYFIATGEEAKQEAFKLLATVREEGYSAVMDFERRSMRAQMKRANKANARFSLILGEAELNEQTCQIKDMEAGEQFQVPLKSFEERIKEIAG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_LACDA
Sequence: MLNGHVVNYGQHRTRRSFSRIKEILPLPNLTDVQTESYKWFLDEGVKEVFDDILPISDTSGRLTLEYVDYKLQEPKYTVDESRKHDATYSAPMHVTLKLTNHETGEIKTQDVFFGDLPLMTKSGSFIVNGAERVIVSQLVRSPGVYYSGEFDKNGRQIFGTTVIPNRGAWLEFETDAKNISYVRVDRTRKLPLSVLVRALGFGSDSEIKEIFGDSDTLDLTLDKDVHKNPADSRVAEALKDIYDRLRPGEPKTTDSSRSLLVSRFFDPRRYDLAAVGRYKVNKKLSLKNRLLGYTLAETLADPGTGEVLAAKGTVVNNEVMDVLKDYLDRDDFKTVTYTPSDEGVIPEPVTVQEIKVFSREIPDREIKLISNGHIAEDVKCITPADIIASVNYFLELQEGVGNIDDIDHLGNRRIRRVGELLQNQMRIGLARMERVVRERMSIQDAATVTPQQLINIRPIVGSIKEFFGSSQLSQFMDQNNPLGELTHKRRMSALGPGGLSRDRAGYEVRDVHYTHYGRLCPIETPEGPNIGLINSMATYAIINKYGFLETPYRRVSWATHKVTDKIDYLTADEEDNYIIAGANTPLNEDGSFVDDVILCRHREDNVEVSPDRIDYIDVIPKQVVSVTSACIPFLENDDSNRALMGANHQRQAVPLINPHGPLVATGMEYRAGHDSGDALLAEADGEVEYVDANEIRVRREDQTLDTYTLEKYRRSNATKNYNQTPNVKRGDKVVDGQVIANGPSMADGELALGQNPVIAFTTWNMYNFEDAIMLSERLVKEDVYTSIHIEDYDSEARDTKLGPEEITREIPNVGEDALKDLDENGIIRIGAEVHDGDILVGKVTPKGITELSAEERLLHAIFGEKAREVRDTSLRVPHGGGGVVQDVQVFTREAGDELAPGVNTLVRVYIVQKRKIQVGDKMSGRHGNKGTVALIAPVEDMPYLPDGTPVDICLNPMGVPSRMNIGQLLEIHLGRAARALGIHVATPVFDGASEDDVWDFVREAGVDSDGKTVLYDGRTGEPFHNRVSVGVMYYLKLTHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKAYEAIVKGERITKPGVPESFRVLVKELQSLGLDLRVLDSDENEVELRDMDEDSNEHVNIDALSRLAEAQEKKKLAEEEAEIAAEAEAEGSAEGDAAEADADANEAETADDDKASK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: KEULE_ARATH
Sequence: MSYSDSDSSSHGGEYKNFRQITRERLLYEMLRSAKTGSSKSTWKVLIMDKLTVKIMSYACKMADITQEGVSLVEDIFRRRQPLPSMDAIYFIQPTKENVIMFLSDMSGKSPLYKKAFVFFSSPVSKELVGHIKKDSSVLPRIGALREMNLEFFAIDSQGFITDHERALEDLFGDEETSRKGDACLNVMASRIATVFASLREFPAVRYRAAKSLDASTMTTLRDLIPTKLAAGIWNCLAKHKQSIENFPQTETCELLILDRSIDQIAPVIHEWTYDAMCHDLLNMEGNKYVHVIPSKSGGQPEKKDVLLEEHDPIWLELRHAHIADASERLHDKMTNFLSKNKAAQLQGKRDGAELSTRDLQKMVQALPQYSEQIDKLSLHVEIARKLNDLIREQGLRELGQLEQDLVFGDAGMKDVIKYLSTQEEASREGKLRLLMILATIYPEKFEGEKGQNLMKLAKLSSDDMTAVNNMSLLGSAVDAKKNTPGGFTLKFDLHKKKRAVRKERQEEAAWQLSRFYPMIEELIEKLSKGELPKEDFPCMNDPSPSFHGSTSLSSAASSSQGQAAQSMRSRRTPTWAKPRGSDDGYSSDSVLRHASSDFRKMGQRIFVFIVGGATRSELKVCHKLSTKLKREVILGSTSLDDPPQFITKLKLLTANDDLSLDDLQI
What is the function of this protein?
Regulator of vesicle trafficking involved in cytokinesis and root hair development, but not required for cell elongation.
What are the official names of this protein?
SNARE-interacting protein KEULE.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, phragmoplast. Note=Localized with its membrane receptor. During cytokinesis, localizes to the cell plate from a very early stage of cell plate formation and until the cell plate reaches the parental cell wall.
Protein: NDUV2_NEUCR
Sequence: MATKLTPFLMRTAVRAATRLSTKPSTIAPVSRACLSISARRPSDTLMVHRNTPDNNPDIPFKFSADNEKVIEEIIKRYPPQYKKAAVMPLLDLGQRQHGFCSISVMNEVARLLEMPPMRVYEVASFYTMYNRTPVGKFHVQACTTTPCQLGGCGSDVIVKAIKEHLGIKQGETTPDGLFTFIEVECLGACANAPMVQINDDYFEDLTPETIKQVLSALKESVTDVSKAPQPGPQSGRQTCENAAGLTSLTSEPYGPEVTRSDL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 24 kDa subunit, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: SYT_STRT2
Sequence: MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKLIDTTRVITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGFYYDTDNQAGQISNEDLPRIEEEMKKIVKENFPSIREEVTKDEAREIFKNDPYKLELIEEHSEDDGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLNVAGAYWRGNSDNAMMQRIYGTAWFDKKDLKAYLKRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRELERYIVDKEVAAGYQHVYTPPIASVELYKTSGHWDHYREDMFPPMDMGDGEEFVLRPMNCPHHIEVYKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHTFVAPEQIEEEFKKILQLIIDVYEDFNLTDYRFRLSYRDPADKHKYFDNDEMWENAQRMLKAAVDDMGVEYYEAEGEAAFYGPKLDIQVKTALGKEETLSTIQLDFLLPERFDLHYIGADGEEHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVAKKLRDRGVRAEVDERNEKMQFKIRASQTQKIPYQLIVGDKEMKDGTVNVRRYGQKQTHTETVSEFVENILADIARKSRPDAE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FENR_SYNY3
Sequence: MYSPGYVATSSRQSDAGNRLFVYEVIGLSQSTMTDGLDYPIRRSGSTFITVPLKRMNQEMRRITRMGGKIVSIKPLEGDSPLPHTEGIAKPSQSEGSGSEAVANPAPESNKTMTTTPKEKKADDIPVNIYRPKTPYIGKVLENYPLVREGAIGTVQHLTFDLSAGDLRYLEGQSIGIIPPGEDDKGKPHKLRLYSIASTRHGDFGDDKTVSLCVRQLEYQNEAGETVQGVCSTYLCNIKEGDDIAITGPVGKEMLLPPDEDANIVMLATGTGIAPFRAFLWRMFKEQHEDYKFKGLAWLIFGIPKSENILYKDDLEKMAAEFPDNFRLTYAISREQQNAEGGRMYIQHRVAENAEELWNLMQNPKTHTYMCGLKGMEPGIDEAFTALAEQNGKEWTTFQREMKKEHRWHVETY
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes.
Protein: SK1_LUCGR
Sequence: EQFEDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, LucGr-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATG1_YEAS7
Sequence: MGDIKNKDHTTSVNHNLMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFEEFFANKVVNEDLSSYELEDDLPELESKSKGIVESNMFVSEYLSKQPKSPNSNLAGHQSMADNPAELSDALKNSNILTAPAVKTDHTQAVDKKASNNKYHNSLVSDRSFEREYVVVEKKSVEVNSLADEVAQAGFNPNPIKHPTSTQNQNVLLNEQFSPNNQQYFQNQGENPRLLRATSSSSGGSDGSRRPSLVDRRLSISSLNPSNALSRALGIASTRLFGGANQQQQQQQITSSPPYSQTLLNSQLFHELTENIILRIDHLQHPETLKLDNTNIVSILESLAAKAFVVYSYAEVKFSQIVPLSTTLKGMANFENRRSMDSNAIAEEQDSDDAEEEDETLKKYKEDCLSTKTFGKGRTLSATSQLSATFNKLPRSEMILLCNEAIVLYMKALSILSKSMQVTSNWWYESQEKSCSLRVNVLVQWLREKFNECLEKADFLRLKINDLRFKHASEVAENQTLEEKGSSEEPVYLEKLLYDRALEISKMAAHMELKGENLYNCELAYATSLWMLETSLDDDDFTNAYGDYPFKTNIHLKSNDVEDKEKYHSVLDENDRIIIRKYIDSIANRLKILRQKMNHQN
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes.  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.  Finally, ATG1 is also required for the maintenance of cell viability under starvation and for glycogen storage during stationary phase.  Plays a role in genome stability through suppression of abnormal mitosis under starvation, and in regulation of filamentous growth.
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=Formes punctate structures in starvation conditions only when ATG13 and ATG17 were both present. Localizes to both the isolation membrane (IM) and the vacuole-isolation membrane contact site (VICS) during IM expansion. The IM is a membrane sac generated from the pre-autophagosomal structure that ultimately expands to become a mature autophagosome.
Protein: LAP3_ARTBC
Sequence: MKVSAIAAVAALAAVAVAGPVRPSGDKYLIELGPGKTQWVTKDQKHKMRAAGQTFIDITNEIGTNFVATKPVAANYPKNIAHPSMVSSMIANLSKENLMRDLQAMSEFNNRYYESQTGVESANWLMEQVKKVIDESGAQGAKVEKIENQFNQFNIIATIPGSSESTVIVGAHQDSINQEDPMGGRAPGADDNGSGSVVVLEALRGVLGSKAFRAANNTNTLEFHWYAGEEGGLLGSQTVFSKYKSDGRQVKAMLNQDLAGFKGQGQEQFGLITDNTNQELNQFCKMIVEKYASIPIVDTECGYACSDHASADRNGFPASMVAETAFEDSNPHIHSADDTVEYLDFDHMLEHAKVALGFMTELGMASNL
What is the function of this protein?
Probable extracellular aminopeptidase which contributes to pathogenicity.
What are the official names of this protein?
Probable leucine aminopeptidase ARB_03492, Leucyl aminopeptidase ARB_03492.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PRIB_SALEP
Sequence: MTNRLALSGTVCRAPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).  During primosome assembly it facilitates the complex formation between PriA and DnaT.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: 3HAO_LODEL
Sequence: MPLPEPLNIKAWVEENEHLLKPPVNNFCLHRGGFTVMIVGGPNERSDYHINQTPEYFYQYKGTMCLKVVDEGKFRDIYIREGDTFLLPPNVPHNPCRFENTVGIVVEQDRPKGVNDRIRWYCARCESIVCEEEFYLTDLGTQIKDAIVAFDSNIEAKTCKNCGHVNSSKREPAEF
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD, Biosynthesis of nicotinic acid protein 1.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y461_RICCN
Sequence: MTTRKDKPLNIYHTLVSIIIPVYNGANYMKEAINSALAQTYKNIEIIVVNDGSKDNGETERVALSYGDKIRYFYKENGGCGSALNYGIKNMQGEYFSWLSHDDIYYPNKIEHQVDILNKLDNKDTIIYGGYELIDEKGNSLRYIKPDSVLPINKLNISLLPLLRGLIHGCSLLMPAKYFHEVGIFNEALPTTQDYDLWFKIFRVAPIHFDESILIKSRFHSEQGSKKISNHNEECNVLWSSFLHELTEEEMIKMEGSPYLFLTRTATFLSNNTPYKKACDLANTMAKQVLNDTKISVIIPVYNRINWAIEAIKSVLIQTHKNFEILIIDDGSTDDISELTAICKKDKRIKYFHKKNEGPAAARNLGIKNAIGKYIAFLDSDDLFYKDKIEIQLKFMEENNFIFSHTSYHKINEKGKYIESVHSGLFSGNVFPQVIQTCPIAMPTVMGTLTLFQENLFPENIRSGEDCCLWISIASKNSIGGIDKELSKVRISGGTNTFMDPNKYSVGLINITSYVLNDAYLSKFSPFTINLLLAAVTQLRLLENKNEDYKKSNISFFKNNYVIQKIRTYCFVTKILILLTITSIRQEGIRATISRIQRWLKKHI
What are the official names of this protein?
Uncharacterized glycosyltransferase RC0461.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: STK38_HUMAN
Sequence: MAMTGSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDILKPTVATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK
What is the function of this protein?
Negative regulator of MAP3K1/2 signaling.  Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2.
What are the official names of this protein?
Serine/threonine-protein kinase 38, NDR1 protein kinase, Nuclear Dbf2-related kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.