PharMolix/UniProtQA huggingface dataset:
Protein: MURQ_PECAS
Sequence: MNGENLNLGTLVSETRNPATMTLDQLSTLEMMQVFNQEDRKVPEAIAQVLPAIAEAVDLATASLQAGGRLIYLGAGTSGRLGVLDASECPPTFGVPHGLVIGLIAGGPGALLKAVEGAEDDPALGEADLKALSLTATDMVIGLAASGRTPYVIGALRYARDVGCRTAAISCNPHSPIAQEAQVAISPVVGPEALTGSTRLKSGTAQKLVLNMISTGVMVKLGKVYQNLMVDVKATNVKLLDRACRIVVEATGADLDSARQALEQSDNDVKPAILMLLANIGVEAARERLKQHNGYLREALLGG
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: HIS5_BACC2
Sequence: MIAIIDYGMGNIRSVEQALKYIGAEHIVTSDKEEILRSDGVILPGVGAFPKAMEVLEERDLVCVLKEVCDIGKPLLGICLGMQLLFERSEELKGCSGLGLLPGEIRKLKVSYKIPHMGWNELRKEREFPLWNGLVDGSFVYYVHSYYADCPDEIVCGVSDYGMQVPGFVAKGNVFGAQFHPEKSGEIGMQILKNFQGVVEAWKSSRLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN6A_ARATH
Sequence: MAPSSSSGLTFKLHPLVIVNISDHYTRVKTQLNPPASICASGHGSNNGEAMFQQNPRVYGCVIGVQRGRTVEIFNSFELLYDPSTQTLDRSFLEKKQELYKKVFPDFYILGWYSTGSDAEESDMHIHKALMDINESPVYVLLNPAINHTQKDLPVTIYESELHVIDGIPQLIFAHTSYTIETVEAERISVDHVAHLKPSDGGSAATQLAAHLTGIHSAIKMLNSRIRVLYQNLAAMQKGDKSCDNSVLRQVSSLLRRLPAMESERFQDNFLMEYNDKLLITYLAMITNCSSNMNEMVDKFNTAYDRNTRRGGRTAFM
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes.  The complex is also required for degradation of PSIAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.  Essential for the structural integrity of the CSN holocomplex (PubMed:17307927).
What are the official names of this protein?
COP9 signalosome complex subunit 6a, AtCSN6a, Signalosome subunit 6a.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISPH_MICAN
Sequence: MDTKSFKRTLQQSDNYNRKGFGHKEEVMDAMTNEYQSDLIQEIRENNYRLQRGDVTIYLAQAFGFCWGVERAVAMAYETRQHFPQERIWITNEIIHNPSVNQRLRSMAVGFIPVENGQKDFTVVESGDVVILPAFGASVSEMQILNDKGCMIVDTTCPWVSKVWNSVEKHKKSDHTSIIHGKYNHEETIATSSFAGTYLIVLNLDQANYVANYILHGGDKNEFLEKFKNAHSQGFDPDRDLDYIGIANQTTMLKSETEEIGKLFEHTMLRKYGPIDFKDHFMSFNTICDATQERQDAIFELVKEPLSLMVVIGGYNSSNTTHLQEIAIERAIPSYHIDSAERILPGNRIEHKPLGDDLIITDNWLNEGKIVVGVTSGASTPDKVVEEVIEKIFAFKSSLVPG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: LYS9_MAGO7
Sequence: MATKSVLMLGSGFVTRPTLDVLTDSGIKVTVACRTLESAKKLSAGVQHSTPISLDVNDDAALDAEVAKHDLVISLIPYTFHATVIKSAIRQKKHVVTTSYVSPAMMELDQAAKDAGITVMNEIGLDPGIDHLYAIKTIEEVHAAGGKIKTFLSYCGGLPAPESSDNPLGYKFSWSSRGVLLALRNAASFYKDGKVTNVAGPELMATAKPYFIYPGFAFVAYPNRDSTPYKERYQIPEADNIVRGTLRYQGFPQFIKVLVDIGFLSDEEQPFLKEAIPWKEATQKIVKASSASEQDIVSTIVSNATFESTEEQKRIVAGLKWLGIFSDKKITPRGNALDTLCATLEEKMQFEEGERDLVMLQHKFEIENKDGSRETRTSSLCEYGAPIGSGGYSAMAKLVGVPCAVAVKFVLDGTISDRGVLAPMNSKINDPLMKELKEKYGIECKEKVVA
What are the official names of this protein?
Saccharopine dehydrogenase [NADP(+), L-glutamate-forming], Saccharopine reductase.
What is the protein family that this protein belongs to?
Belongs to the saccharopine dehydrogenase family.
Protein: ACP_PORPU
Sequence: MQDNEIFEKVQDIVAEQLGIEKTIVTREANFSSDLGADSLDTVELVMAIEEKFAIEIPDEDAEKITNLSEVVDFIKSKLNTISV
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AL1B1_PONAB
Sequence: MLRFLAPRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNCLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPIGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKMEEVIERANTTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS
What is the function of this protein?
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde.  They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity).
What are the official names of this protein?
Aldehyde dehydrogenase X, mitochondrial, Aldehyde dehydrogenase family 1 member B1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TYRO_MOUSE
Sequence: MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILLSSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIRRNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRDAENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQSSMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGHNRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLGAALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
What is the function of this protein?
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds (PubMed:2517217).  Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine (PubMed:2517217, PubMed:1537333, PubMed:35469906).  In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone (PubMed:1537333).
What are the official names of this protein?
Tyrosinase, Albino locus protein, Monophenol monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Note=Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Protein: MOT2_MESAU
Sequence: MPSETAVPPPHPIPPDGGWGWVVVGAAFISIGFSYAFPKAVTVFFKDIQQIFQASYSEIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIIGGLLCCTGMILASFSNSVLELYLTIGFIGGLGLAFNLQPALTIIGKYFYRRRPMANGLAMAGSPVFLSSLAPFNQYLFNSYGWKGSFLILGGIFLHSCVAGCLMRPVQTSPRKSKSKSKVGSRQDGSMKKASKVSTAEKINRFLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDKGVDEYNAALLLSVMAFVDMFARPTGGLIANSKLIRPRIQYFFSFAIVFTGICHLLCPLADTYPALVVYSIFFGYGFGSVSSVLFETLMDLVGPARFSSAVGLATIVECCPVLLGPPLAGKLVDKTKDYKYMYIASGTIVVISGIYLFIGNAINYRLLAKERKREKARKKKSATHPSRESEALSRSKQDDVSVKVSNPHNSPSDRERESNI
What is the function of this protein?
Proton-coupled monocarboxylate symporter (PubMed:7829520).  Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate.  Dimerization is functionally required and both subunits work cooperatively in transporting substrate (By similarity).
What are the official names of this protein?
Monocarboxylate transporter 2, MCT 2, Solute carrier family 16 member 7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TYPH_ECOSE
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: CCME_NITEU
Sequence: MKPRHKKMAVIALSVSALTVAVVLVLNAFQSNLVFFFSPSQVAAKEAPIGKSFRIGGLVEEGSLKREGDGTTLNFAITDTAEVIRVVYTGILPDLFKEGKGVVAQGKMADDGIFYADEVLAKHDENYMPPEAASALEQAAKAQKTSLAQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RL31_ECODH
Sequence: MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRDVATGGRVDRFNKRFNIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RR16_HUPLU
Sequence: MVKLRLKQYGGKQQATYRIVAIDARSRGXGRAIQEVGSYDPIKDQTQXNMPTIVYFIERGAQPTETVKDILQKAEIFAQLRAKS
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UGTP_STAAE
Sequence: MVTQNKKILIITGSFGNGHMQVTQSIVNQLNDMNLDHLSVIEHDLFMEAHPILTSICKKWYINSFKYFRNMYKGFYYSRPDKLDKCFYKYYGLNKLINLLIKEKPDLILLTFPTPVMSVLTEQFNINIPVATVMTDYRLHKNWITPYSTRYYVATKETKQDFIDVGIDPSTVKVTGIPIDNKFETPINQKQWLIDNNLDPDKQTILMSAGAFGVSKGFDTMITDILAKSANAQVVMICGKSKELKRSLTAKFKSNENVLILGYTKHMNEWMASSQLMITKPGGITITEGFARCIPMIFLNPAPGQELENALYFEEKGFGKIADTPEEAIKIVASLTNGNEQLTNMISTMEQDKIKYATQTICRDLLDLIGHSSQPQEIYGKVPLYARFFVK
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer two glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RS18_GEOKA
Sequence: MAGRKGGRGKRRKVCYFTANNITHIDYKDVDLLKKFISERGKILPRRVTGTSAKYQRKLTVAIKRARQMALLPYVADE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: FABR_ECO57
Sequence: MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB1_BURCH
Sequence: MNATTSAAAYGPLAGADLEAELAQARVADSDARDAAILEHDGSASVVPLARRRTSGTAPDDAVTLSGVSKRFGARTVLDNVELGIARGSFVAIVGRSGCGKSTLLRLVAGLEQPSSGALVTRGEGGGALDTRIMYQDARLLPWKTVLQNVMLGLGRGARDQARAVLDEVGLLERANDWPAQLSGGQRQRVALARALVHRPQLLLLDEPLGALDALTRIEMHALIERLWREHRFTALLVTHDVQEAVALGDRILLIEQGRVALDQAVPLDRPRARASAAFAALEDRVLKRVLAGGPGAADHDAEHEADKVRPVGQIRWAV
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EFTU2_XANCP
Sequence: MARAKFLREKLHVNVGTIGHVDHGKTTLTAALTKIGAERFGGEFKAYDAIDAAPEEKARGITISTAHVEYESAVRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPHIVVFLNKADMVDDAELLELVEMEVRELLSKYDFPGDDTPIIHGSARLALEGDQSDIGVPAILKLVEALDTFIPDPTRDVDRPFLMPVEDVFSISGRGTVVTGRIERGIIKVGDEIEIVGIRDTQKTTVTGVEMFRKLLDQGQAGDNAGLLLRGTKRDDVERGQVLCKPGSIKPHTEFEAEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDITGACQLPEGVEMVMPGDNVKMVVTLINPVAMDEGLRFAIREGGRTVGAGVVAKIVK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu-B, EF-Tu-B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_YERPP
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQERMAASRPYAETMRSVIGHLALGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKRLLAEMKGWSEKGVECDLALIGSKAASFFGSVGGKIVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVNNKFINTMSQEPRIMQLLPLPPAEDGELKKKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVGGASAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UNC8_CAEEL
Sequence: MSPLLTWNLICVSSRWYTILCLKNKVKFWLGTRLVHEPESMESRSSPYIRPSPYAGGVHPHFEEEDDRSKLHASALYSERRTSSRKSLRSQKIDYHTTTIKSLWFDFCARTSSHGIPYVATSSFFGRYVWAALFMCMLMAFLLQTYWTMSEYLQYRTIIEMQLQFEAAAFPAATVCNLNAFKYSELTQYEEIKEGFDYWERVINARMMSDSMKPGGDILEAISVRKKRSKSRDQLLFPIDDEDLEGAVYQPVFVRCTCMNMEQCVPNRNPLEVNASICMCFEDVTRGLIWPCYPTSVWTVKKCSGCSISNTCPDPDGPNASKQIAKHNSPLPCLCQSISHHCMVHPKDEIRWWNPNNYTVYSVTEPPTTEITETEEAFGLSDLKDAGAITTQTKENLIFLVAALPRETRRNLSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYGNCYTFNFNDSVELKNSRAGPMYGLRLLLNVHQSDYMPTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDTFRPVPYIYNEHYSPEGCHRNCFQLKVLEICGCGDPRFPLPSEEHRHCNAKSKIDRQCLSNLTSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNFKIGTDCPAVSDIFNDTEACTEYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAELFCEICKLMYFKGIVYVQKKMQGKEYTSSSLMHIDFLQRSPKKSQPGEDEVSTNESTKELMSK
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel (By similarity).  Involved in the activity-dependent removal of selected presynaptic proteins, such as synaptobrevin snb-1, and Ras-related rab-3, in the remodeling of GABAergic motor neurons (PubMed:34045310).
What are the official names of this protein?
Degenerin unc-8, Putative ligand-gated sodium channel unc-8, Uncoordinated protein 8.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CHVI_RHIRD
Sequence: MQTIALVDDDRNILTSVSIALEREGYRVETYTDGASAVDGLIARPPQLAIFDIKMPRMDGMELLRRLRQKSDIPVIFLTSKDEEIDELFGLKMGADDFITKPFSQRLLVERVKAILRRASSREASAATGGTLKPTADQQARTLERGQLAMDQERHTCTWKGEPVTLTVTEFLILHSLAPAAGRGEKRDALMDAAYDEQVYVDDRTIDSHIKRLRKKFKLVDGDFDMIETLYGVGYRFAEAA
What is the function of this protein?
Member of a two-component regulatory system ChvG/ChvI.
What are the official names of this protein?
Transcriptional regulatory protein ChvI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LONM_KLULA
Sequence: MLRSSRSRLVTRNILLRQFKNGNNVRLMNATRFQHNGIVGNEKLASDSQKFVDESYHWMQYRKQMNDPVSRQRLEQLESQWVKSIQLKQDDKGKDIDQPESENRKKEEEQVPTEEKDNDTAKESETSQQRDSVAETQGPASTSGGASGNGESSGNGSGDDGNNGSGNGKPSKNAKQPFPEVYPQVMALPISRRPLFPGFYKAVVISDERVMKAIKDMSDRQQPYIGAFLLKDSTVDTDVIHKADEVYNVGVFAQVTSAFPSKDEKTGAETMTALLYPHRRIKLDELIPPTSEQNLKDESDVSKSEGVENNEQEVVKASLQKMENMKDVEEDDDENLTGFLKDYDVSLVNVSNLADKEFNPNSPVINALTSEILKVFKEISQLNTMFREQIATFSASIQSATTNIFEEPARLADFAAAVSAGEEEELQEILESLDIEQRLEKALTVLKKELMNAELQNKISKDVETKIQKRQREYYLMEQLKGIKRELGIDDGRDKLIESFKDRVSKLQLPETVQKVFDDEITKLATLETSQSEFGVIRNYLDWITSLPWGIISKEQYSIPKAKKILDEDHYGMKDVKDRILEFIAVGKLLGKVDGKIICFVGPPGVGKTSIGKSIARSLNRQFFRFSVGGMTDVAEIKGHRRTYIGALPGRVIQALKKCQTQNPLILIDEIDKIGHGGIHGDPAAALLELLDPEQNNSFLDNYMDIPIDLSKVLFVCTANSLETIPRPLLDRMEVIELTGYVAEEKVKIAENYLSPSAKKSAGLDNANVNITENAIVSLMKHYCRESGVRSLKKHIEKIYRKAALNVVKQLSIDDKPMENEEVKDQKDIKVKQSENKSSAEASTVESTTEENELIKTQKSHDNKGSLEVPETVSVTVDENNLKDYVGPPIFTTDRLYESTPPGVVMGLAWTSMGGCAMYVESVLEQPLTHSTQPTLERTGQLGDVMKESSRLAYSFSKMYLAKKFPENRFFEVAKIHLHCPEGATPKDGPSAGVTMASSFLSLALNKGLDPTVAMTGELTLTGKVLRIGGLREKAVAAKRSGAKTIIFPKDNLSDWAELPENVKEGLEPLAADWYEDVFQRLFGDVDTNKGNTVWSEDFKKIDEKRNKETK
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.
What are the official names of this protein?
Lon protease homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NDC80_GIBZE
Sequence: MSQDTGLWSVRRPRETLGGISANSAIPQPGSTMKRSSSNIGGNYPGSHVRSMSGSRHSLAMPRPSQPMFQRSSSGTNLVDLGLSSVKRSSFAPKSTFTPGTATKRASTDGDRRSSVYRPRQSTVPAVSHHQSFFQTTPAPAGVPRDPRPLKDRSFQARIGQEIMEYMVQHNFEMEMKHVLSQNVLKSPTQKDFNYMFQWLYHRIDPSHKFQKNIDQEVPPLLKQMRYPFERSITKSQIAAVGGQNWSTFLGLLHWMMQLAQMLDGYVNCQYDEACMEAGIDVSGDRIIFDFLSNGYRDWLAMDEDLGDEEAERVLAPHVQSMAAAFERSNSKYTSELDMLEAENARLLKEIEDLEKSTPDPAVLDHHFKIMEEDKVKFEEYNALAMQRSEKYESRSQVLQEELDKLLEELQEADEERRSLQKAVDAQGISMQDIDRMTAERERLQRGIESASQRLEEVKKKVSEREAEASRKLDELEQMVDRYNTMAYQIALIPSTAANAKGREFELQVTVADDSDFTTSIMKSGPSSADRLVVDSTTGHQAGHILNLDLRGKIRNSFISLRKEISDRRATAMDEMIKDHDLLDGIKEAIEDRRGEVEALNHRVRAAEEEYEKTKEVTTAQKLASDAHIEKMEKELSRMRAGLSENVQILEQREINTTIEYEQLVLQANALREELHTEIDRMLNDVIKFKIHVQKSLDDYEGFVTEELEKELGSDEMQEDTQRMDM
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein NDC80.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: FGF6_MOUSE
Sequence: MALGQRLFITMSRGAGRVQGTLQALVFLGVLVGMVVPSPAGARANGTLLDSRGWGTLLSRSRAGLAGEISGVNWESGYLVGIKRQRRLYCNVGIGFHLQVPPDGRISGTHEENPYSLLEISTVERGVVSLFGVKSALFIAMNSKGRLYTTPSFHDECKFRETLLPNNYNAYESDLYRGTYIALSKYGRVKRGSKVSPIMTVTHFLPRI
What is the function of this protein?
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.
What are the official names of this protein?
Fibroblast growth factor 6, FGF-6, Heparin secretory-transforming protein 2, HST-2, HSTF-2, Heparin-binding growth factor 6, HBGF-6.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: BACT_STRMG
Sequence: KYYGNGVTCGKHSXSVDWSKATTNI
What is the function of this protein?
Bactericidal activity against a wide range of pathogenic bacteria, including Bacillus spp. , Enterococcus spp. , Listeria spp. , Staphylococcus spp.  and Streptococcus spp (PubMed:21477375).  Has no activity against Lactobacillus salivarius, Staphylococcus aureus, Streptococcus pyogenes and Streptococcus suis (PubMed:21477375).
What are the official names of this protein?
Bacteriocin mutacin F-59.1.
What is the protein family that this protein belongs to?
Belongs to the bacteriocin class IIA/YGNGV family.
What are the subcellular locations of this protein?
Secreted.