PharMolix/UniProtQA huggingface dataset:
Protein: COL12_CHICK
Sequence: MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCVLLTITIAILGYKVVEKMDNVTGGLETSHRRYTEKLTEVESDLKKLDDQAGQKALNTNTELSSFRSDILALRQQLHDIAEKTTRNKDTLEKLQESGNVLDDRQSQIRSALDSNSFMIISVNKTLQAYTGYINNLQQDTSNIQSDLQNQVHSHNVVIMNLNNLNLTQIQQRNLISVLQKSMEDKSLAILRIKNDFQNLQQVVLQARKDTDWLKEKVQNLQTLAANNSALAKANNDTLEDMNNQLSSFSGQMENISTIAQANEQNLKDLQEQHKEYENRTSAKFNQLEERFQVFETDIVNIISNISYTAHHLRTLTSNLNEVRTTCTDTLSKHSDELIFMNSTLANIRLDSASLKMQQDLMRSRLDVEVANLSVIMEEMKLVDSKHGQLIKNFTILQGPPGPRGPKGDRGPQGPLGPAGLKGQKGEKGEPGPPGPAGEKGPPGPIGPPGEKGGKGSRGSPGSKGQRGSPGKTGLPGPSGDPGPPGPQGKDGPQGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGLPGPKGPPGPPGPPGPGMPMALQSEPTSVPEANGCSPHWKNYTEKCYYFSIEREIFEEAKLFCEEKASRLVIINNKEEQQWIKRQISGKGSFWIGLTDSEKENEWRWLDGSLPLYTNWKTGQPDNWNHGHGPGEDCAGLIYAGLWNDFYCEDVNNFICEKDMDKEQIFGV
What is the function of this protein?
Scavenger receptor that displays several functions associated with host defense.  Binds to carbohydrates (By similarity).
What are the official names of this protein?
Collectin-12, Collectin-3, CL-3, cCL-3.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: PSD_SHEPC
Sequence: MDKVKIALQYMLPKHLLSRLVGKLAAAEAGTLTTAAIKWFIKQYKIDMSEAAQSEPQAYKSFNDFFTRALKPGIRPINQHTNIMVHPVDGAVSQLGPIKEGRIFQAKGHHYSSLTLLGDQVQDAKRFEGGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGELFSVNPLTARHVPGLFARNERVVAIFETEHGPLAMVLVGATIVASIETVWAGTITPPTGKQVFTWEYPTVGPDAITLDKGDEMGRFKLGSTVVMLFAKDAIDTFAEGVEAEAVTRMGQAFANLNNPK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y537_LISIN
Sequence: MRAVLTVIGKDNVGIVAGVSNKLAELNINIVDVSQTIMDGYFTMMMMCDISQITKEFDEVKTELTGKGEELQVKIHIQREEIFNAMHKL
What are the official names of this protein?
UPF0237 protein lin0537.
What is the protein family that this protein belongs to?
Belongs to the UPF0237 family.
Protein: TX1A_PARCV
Sequence: FLPLLILGSLLMTPPVIQAIHDAQR
What is the function of this protein?
Blocks nicotinic synaptic transmission in insect CNS and affects voltage-gated sodium channels (Nav).  It is a strong, but very slowly acting agonist for smooth muscles and its blocks synaptic transmission in the insect CNS in a concentration-dependent manner and depolarizes giant interneurons.  Also affects neuromuscular transmission in rat tissue.
What are the official names of this protein?
Delta-paraponeritoxin-Pc1a, Delta-PPOTX-Pc1a, Pac-TX, Poneratoxin, PoTX, Poneritoxin.
What are the subcellular locations of this protein?
Secreted.
Protein: YBEY_LATSS
Sequence: MDIQIIDETKIVPEAQIKLVEDVLEFAGQKLELAEDTEMSVTFVTNERIRQINQEYRNTDRATDVISFAIEEDPEEEGLPANFEELFDIPKNIGDLFVSLEKAAEQAETYGHSFERELGYTMVHGFLHLNGYDHIHTEDEVKMIPLQETILDEFGLKR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QVR_DROGR
Sequence: MWTKANAAGKGLLTLAAIFGFLTFVWIPSASAECQTRSIYCYECDSWTDARCKDPFNYTALPRDQPPLMTCNGCCVKMVRHQRSRYEVVRRMCTSQLQINLFMVDHVCMMESSGNGHMCFCEEDMCNSSKSLYSFANGYNHLIIITLTPWLKLLLQQFVHR
What is the function of this protein?
Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation.  Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability (By similarity).
What are the official names of this protein?
Protein quiver, Protein sleepless.
What is the protein family that this protein belongs to?
Belongs to the quiver family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: DYR_CAEEL
Sequence: MRKMNLIVAMDAEGGIGKNGVLPWRIKKDMQYFASVTKNVSDQSKRNAVLMGRKCWESIPVTRRPLAGRLNIVLSRQLPAQKSDDYIVVNSLEAAMKLLSEPPFVDSIETIWNIGGAEIYDLALRENLVDEIHLTRIFKNFEADVHLKSLDFSKMEKVQNAEVSSENSEIFEENGLKFEFCKWKVVENH
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Putative dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: RS3_TRIEI
Sequence: MGQKIHPTGFRLGITQEHRSRWYADPKNYPDTLQEDHKIRQYVKATLANAGISQIRVERKAEQIDLEVRTARPGVVVGRGGAGIDSLRVGLQKLLGSNRQIRINVVEVTKVDTDAMLIGEYIAQQLEKRVSFRRVVRQAITRAQKAGVEGIKIQVSGRVNGAEIARTEVTREGSVPLHTLRANIDYAYCTAKTIYGILGIKIWVFKGEIIPGQEEIANAKVNQPKRRQQKRRQQYDDRSNEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: FMT_BORHD
Sequence: MRIFFASSESIALEVLKKVADQHNVVGVLTAPDKPSGRGLFLRANDIKVEATNRNITVLDPVVLNSDVVEIVKRLNPDLMLVFSYGKIFRQEFLDIFPMGCINVHPSLLPKYRGPSPIQTAILNGDTVGGITVQKMALEMDSGNILSQSQFEIKSFNTSADIFRYVSLNSFNLVLEALSKLDKGNIGIEQDSRQATYCSFFNKQHRILDFNLSAFEIKNKINACNPWPLARAKLDDDEIIFHRADFIRTNDYSDQAIGKIILFDPSRGILVKTGDGILLLLELQRAGRKVMDYKSFYNGNRDLIGKIFS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: THIC_CUPTR
Sequence: MARTAPAASFESLESDLDQKFAYPASSKTYLTGSRPDIRVPLRTILQTSTRTEKGEMPNPPIPVYDTSGPYSDPDVHIDLKAGLPPVRAKWIEERGDTEVLPGLSSEYGRDRANDPATAHLRFAQLTNPRRAKAGANVSQMHYARKGIITPEMEYVALRESLNLQALYDKPEYKALLRQHPGNALGAGLPLRPEDITPEFVRQEIASGRAIIPANINHTELEPMAIGRNFRVKINGNLGNSAVTSSLAEEVEKMVWSIRWGADTIMDLSTGKHIHETREWILRNSPVPIGTVPIYQALDKTGGIAEDLTWEMFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTADRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADSNDDAQFGELRTLGELTAKAWKHDVQVMIEGPGHVPLQRIQANMDEELKHCYEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWMGTAMLCYVTPKEHLGLPDKEDVREGIITYKIAAHAADLAKGWPGAQLRDNALSKARFEFRWEDQFNLGLDPERARSYHDATLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYAASLPKEAQQGMEEKSIEFLKKGSKIYS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RL5_ACIBY
Sequence: MARLKARYNDELKAKLQEELSIKNVMEIPRITKITLNMGVGAAATDKKLLDGAVADMQLIAGQKPVVTLARKSIAGFKIRDGWPIGCKVTLRGDQMYEFLDRLISIAIPRIRDFRGFSAKSFDGRGNYSMGLKEQIVFPEIDFDKIDRIRGMDITITTTARTDDEGRALMRAFGFPFK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SYW_KLEAE
Sequence: MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQHAITVRQDPQQLRKATLDTLALYLACGIDPQKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNQVPVGEDQKQHLELSRDIAQRFNAIYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEPPVVRYDLKEKAGVSNLLDILSAVTGKTIPELEQHFEGKMYGHLKGEVAEAVSGMLIDLQERYHRFRNDEAFLNQVMKDGAEKASARASQTLKAVYEAIGFVAKP
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_PECCP
Sequence: MKYELQTTDGRARRGRLIFERGVVETPAFMPVGTYGTVKGMTPEEVKDTGAQILLGNTFHLWLRPGQEIMKLHGDLHDFMQWHGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDSIFLSPEKSMEIQHDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRQRFDELENKNALFGIIQGSVYEDLRDVSVKGLVDIGFDGYAVGGLAVGEPKEDMHRILEHVCPQIPEDKPRYLMGVGKPEDLVEGVRRGVDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKDDVSPLDEHCDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRQAIEEGKLEHFVVDFYQRIGKPIPPLAEKDVAAGN
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PYRH_RHOP5
Sequence: MAEPVYHRVVVKLSGEYFAGDQSFGIHQPTIDRIAGDLIAAQQLGVEIAVVIGGGNIFRGVEVSTRGVSRPTGDTMGMLATVMNCLALEAAIERRGVSARTLSAFVMPQVCELFTRATAHRYLAEKRIVLLGGGTGNPFFTTDTTAVLRAAEIGAQAVLKATNVDGVYSADPKKDPSAQRFERLTHSQALDGGYKVMDATAFALARDTLLPIIVFSIAEPGSVGAILSGTGRGTIVAG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_BORBR
Sequence: MTTAENRARLVLGNWKMHGNLAENAALLAELRAADAAAHCEMGVCVPFPYLAQTAAALQGSAIGWGAQDVSAHAKGAYTGEVAAPMLAEFGCRWVLVGHSERRTLHAESDQLVADKARAALEAGLTPVVCVGESLQEREGGNTLGVIERQLEPVLALGRDALVRMVLAYEPVWAIGTGRTASPEQAQEVHSAIRVALDGLQASQVRVLYGGSVKGANAASLFAMPDIDGGLVGGASLVAEEFLRIAAA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_CANAL
Sequence: MSQISMFVRKLHKFSYNPNYKFKCGLEIHTQLKTKYKLFSLSPTSYNEPPNTKLSYFDVGLPGTQPLLNPEALLLALKASVALNCDIQSYSSFDRKHYFYADQPLGYQITQHYYPLAKNGYVQLNKFDDMPDKVISLEQVQLEQDTGKTVNYDDRINVDLNRANTPLIEVVTKPDFENIDQVQAFVRKYQLLVSHLDICTGDLETGAIRVDANISVNNNPRVEIKNLGSSGEIVDALKYEYNRQVTLLQNNGKIIQETRGWNGIATESLRKKENAVDYRYVPDSELPVIRLDKNIQAQLQNTLDELPDSVLDRLTKEPYNLQLAHARNLLFQPEILDYYENIFGRIRDANKWFFHELLAAFAKSDVEFQVDIVLPDMLVDIVSSVEKNEISLTGARIILKHIIRNKSTKTLPQLIKELDIGKPEASAELEEAINEICQQIINTNADVVEKIARGHTNALQVLIGQAMKATKGKVHAKEFRSKFMELLK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: US20_HCMVT
Sequence: MRVISRARSACTWTSCTSLSPCSTSCPPSPAAPTLLRRRSLPQQRRRPSSSPNRRVRGVTTSPCPTRSLVYKRRVGAPQRLCAETVATMQAQEANALLLSRMEALEWFKKFTVWLRVYAIFIFQLAFSFGLGSVFWLGFPQNRNFCVENYSFFLTVLVPIVCMFITYTLGNEHPSNATVLFIYLLANSLTAAIFQMCSESRVLVGSYVMTLALFISFTGLAFLGGRDRRRWKCISCVYVVMLLSFLTLALLSDADWLQKIVVTLCAFSISFFLGILAYDSLMVIFFCPPNQCIRHAVCLYLDSMAIFLTLLLMLSGPRWISLSDGVPLDNGTLTAASTTGKS
What are the official names of this protein?
Transmembrane protein HWLF3.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US12 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYFB_PYRAB
Sequence: MPKFDVSKSDLERLVGRSFSLEEWEDLVLYAKCELDDVWEENGKVYFKLDSKDTNRPDLWSAEGVARQIRWALGLQSGLPEYEVKESDVVVYVDEKLKNVRPYGVYAIVEGLNLDEDSLSQMIQLQEKVALTFGRRRREVAIGIFDFEKVKPPIYYRAAEKTEKFVPLGFEEELTLEEILEKHEKGIEYGHLIKDKPHYPLLVDSEGNVLSMPPIINSELTGRVTTETKKVFIDVTGWDLKKVMLALNVMVTALAERGGKIRSVKVIYKDFEIVTPDLTPKRFEVELNYIRKLSGLDLKDEEIKELLERMMYSVELEDGKAKLLYPAFRDDIMHARDVLEDVLIAYGYNNIEPEEPKLAVQGRGDPFKDFEDAIRDLMVGFGLQEIMTFNLTNKEVQFKKMNIPEEEIVEIANPVSQRWSALRKWLLPSLMEFLSNNTHEEYPQRIFEVGLATLIDESRETKTISEPKLAVALAGSEYTFTNAKEILDSLMRHLGVEYEIEETEHGSFISGRVGKVLVNGKEVGIIGEIHPQVLENWNIEVPVVAFEIFLRPLYQP
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_METTH
Sequence: MNLRAGRLNSGMEDEAAEFTSSLTFDHHIFEADIECNMAHTRMLAHEGIIPEEVAAKIIDALESLREEGIEALDMDPSVEDIHMAVENYVTARIGEEAGFMHTGKSRNDQVATDLRLALRERIRTISRELLDFIDSISDLALDHTETVMVGYTHLQHAQPTTLGHHLMAYASSLRRDYERLQDTLKRVDQNPLGSAAMTTTSFPINRELTTRLLGFSDYMKNSMDAVSARDFIAETVFDLSMLAVNLSRISEEMILWSTHEFGIVEIPDEFSSTSSIMPQKKNPDVAEIARAKTSTVQGELVTILGIMKALPYTYNRDLQEVTPHLWRAVDTVLSMIRVVRGMLLGIRVNRNRALELAGANFATATDLADIIVRERGIPFRVAHRIVGRLVTRAIEDGLAPGDVDSVYLDEVSLEVTGRKLELDPELVEKALDPLENVRMRRIPGGPAPEMVRVAVEEMKSFIESERK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALM2_HUMAN
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
What is the function of this protein?
(Microbial infection) Required for C. violaceum CopC arginine ADP-riboxanase activity.
What are the official names of this protein?
Calmodulin-2.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
Protein: MU190_SCHPO
Sequence: MSTHSGDSTKQQHYRSSDPYSGRRPIPTIPKFFRDRKQRAEKKEEQQREQTENEKLFDPITQRDVEINDVHFDYAKTYDDPSFTVPNQSIQGSSLPSEKPYLSSNQPTNVYKQHQDDLAPPEADNQITRDVPISDEKTNILFFPSPSIDLSYVSKEVKQKTGQYSLFAYIFSLVISWFFTHSIIISAVLPLAISSCMYLWMQNIYAVAKDAEWGAEQKRGEYARLNLIPESAEWMNHLLEKVWPLINPEMFSSVADQIEDVMQASIPSFVENVRVASLDQGSHPVRVVSIRSLPSGEASESFSEKQASEAEHKDEPEQQRKQFYNFELCLAYHAKPVEDATSTSARASNLHLRIVFYPGIKGTVGFPLPIWVEIKGFVARIRFRCELMPEVPFLKNVTFSLMGLPELNVSAVPVAEGGVNIFGLPLISKFVNDAISAAANEYVSPKSMTIDLSKTLLGDDIKKEVNALGVIFVHINRAEDLSKQDVNGLSDAYITVGFHKFGKPLYCTRVVKQDLNPIWNEYAFIPVFPDQVKAGEKISIELWDSDRFSPDDVVGRTKIGLHLLIQDSGKMHERCDTLTGISEDTSLPGRVFYEIGYFPRAEFKPSLKTSGHDITIPRSMRDDPAFQNPHGSLDNKEEEAAVTTAPDEEYPSGILSFTVHQAVNLQMNHPTGTFGNVSGNYNTSPAQSVGDVTAEEGSELPSSYVCVDLDDTLVYKTRTKVFTSNPIYNAGSEKFVKDWRNAMLCFTVRDFKLREHDSILGVVNIPLATTLTTSSQLTKWYPIQGGIGFGSVRISILFRSMKLKIPRNLLGWDIGTLEFMDRQIVAEGTGSVSDVSFSSIRVNIAGVKITAKSSTSNSSSTAEYHVRSRHAVIPVNNRYRSAVVFEFRKQLQRKHNVFAMVWLVDLEDNVEQNIRVPIFTSSKPAHVLQNMIDFDHPDKESEFKIIGYLSTRICFHRGLDDSHEQLVDNDDEAAIFETYRCLKSMGLRRGYVKDMKNPLADQRASLDESRETTTASSKFESDDSVDTEDEETTTDRTPIECTQTVSMVDPNVNGDIQGRNSLGTMNSNERNLEQEFISLGYASKNRPKAHAQEGTNQPGASENVEPVLADDSDAVTIHSNISSDDQKRKLVNADDRELEKRLHRGPYNSKIVRTGEWVKDGAKMGWRNLRRKFALNGRQPDVETEISK
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 190 protein.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Single- pass membrane protein. Nucleus membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: COA3_TTV1K
Sequence: MVEIKLVNKEIIKFGLALGIVNELNEYLYAAMPPMYDILSKLYGYGRTVNAMLYSVLFNLLESRIDTLRRLDLSKFFAVVAYMDAVKDTVELAINGYAYVTTSGFTVYPASQITGTYESDFSQAKAVPANTTATQVWFAPKKFALITQNKIYTFLAPYWF
What are the official names of this protein?
Coat protein TP3.
What are the subcellular locations of this protein?
Virion.
Protein: YSCA_YEREN
Sequence: MSQITTKHITVLFRRWMAIICCLIIKIAYLAY
What are the official names of this protein?
Yop proteins translocation protein A.
Protein: RIHA_CITK8
Sequence: MALPVLFDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPDKTLRNVLRMLTLLGRNDIPVAGGAIKPLMRDLIIADNVHGESGLDGPALPEPSFAPQTCTAVELMAKTLRESPEPVTIVATGPQTNVALLLNSHPELHRKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHAEDTERFRATGNPVSTIVAELLDFFLEYHKDEKWGFTGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYFLTGNKPNATVMVDIDRQGFVDLLAERLAFYAS
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: M2_I54A1
Sequence: MSLLTEVETPIRSEWGCRCNDSSDPLVAAASIIGILHLILWILDRLFFKCIYRRLEYGLKRGPSTEGLPESMREEYRQKQQSAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: AROA_SALPK
Sequence: MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGGPLRASGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGGDIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLHHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARMSTPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_AERSA
Sequence: KRAIQSEKRRQHNASRRSMTRTYLKKVIAAIASGDKAAAVAAFATAQPIMDRMATKGLIHKNKAARHKSRLS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RSMA_ALIB4
Sequence: MEKVKAKKQYGQNFLKDSTILDKIIQSMPNNNNHIVEIGPGLGDLTKNLVKYKDLTAYEVDTDLIGILKSKFAIEIEKGNLKLIHTDVLEAWDKLKNLHDGKYDLIANLPYYIATNIILRAFEDELCEHIIVMVQKEVAEKFTAKTNDKEYSSLGIITELISINSKILFDVPAEAFDPPPKVTSSILYIKKDMSKSLDKDFNKFLKACFIQPRKKLSKNLTTIFDKNIIFEIYKELNINDNVRPHEVSSSLYSQMYTKVKNGRNK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_PSELT
Sequence: MLVISRKSGESFMIGDSIEVKILRIEGSEVKIGISAPSHVKIYRAEIYQKIVKENKMAVQVDIVDLSEVIFLDRNK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.