PharMolix/UniProtQA huggingface dataset:
Protein: IL2_MOSBE
Sequence: MYKIQLLSCIALTLALVANGAPTSSSTGNTMKEVKSLLLDLQLLLEKVKNPENLKLSRMHTFNFYVPKVNSTELKHLKCLLEELKLLEEVLNLAPSKNLNLREIKDSMDNIKRIVLELQGSETTFTCEYDNATVKAAEFLNKWITFCQSIYSTMT
What is the function of this protein?
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance.  Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG).  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3.  In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5.  This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways.  Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well.  Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production.  Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.  Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
What are the official names of this protein?
Interleukin-2, IL-2, T-cell growth factor, TCGF.
What is the protein family that this protein belongs to?
Belongs to the IL-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRF_XANOM
Sequence: MSRAPLPLAAHERLIFALDVPSHDEAIAWVDRLGDSVAFYKIGMELLASGEYFHVLDALAKRDKRVFVDLKFFDIPATVAGTIRRLAQWPVSYCTVHGWHAGMLQAAADANHGAMRLLAVTVLTSMGRPDLAAMGIDREPVDVVVERALAAEAAGIDGVIASGQEAGPIRRATGPAFSIVCPGIRPGGPVADDQQRIVGVAQAFTDGADAIVVGRPIRLAADPAAAAAAIQAEILAAVGQDRS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL5_CAMJR
Sequence: MMRLKEKYNQSIKPALVKEFDIKNPMLIPVIEKVVISVGAGELAKDQKVLQNVADTISLIAGQKAVITKAKKSVAGFKVREGFPVGVMVTLRKENMYAFLDKLISIALPRVKDFRGLSRDGFDGRGNYNFGLDEQLMFPEVEYDKILRTHGMNISIVTTAQNDKQAQKLLELIGVPFTKGK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RS16_FRAP2
Sequence: MVVIRMARGGAKKRPFYRIVVADKRSPRDGRFIEKLGFFNPLAKGGEERLKLDVAKAEAWLAKGAQPSDRVASLIKEAKKVA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL2_YERPY
Sequence: MAIVKCKPTSPGRRHVVKVVNPELHKGKPYAPLLEKLSKSGGRNNNGRITTRHIGGGHKQHYRLVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVARDGSYVTLRLRSGEMRKVQADCRATLGEVGNAEHMLRVLGKAGASRWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TRPD_SULIY
Sequence: MNINDILKKLINKSDLEIDEAEELAKAIIRGEVPEILVSAILVALRMKGESKNEIVGFARAMRELAIKIDVPNAIDTAGTGGDGLGTVNVSTASAILLSLINPVAKHGNRAVSGKSGSADVLEALGYNIIVPPERAKELIHKTNFVFLFAQYYHPAMKNVANVRKTLGIRTIFNILGPLTNPANAKYQLMGVFSKDHLDLLSKSAYELDFNKVILVHGEPGIDEVSPIGKTFMKIVSKRGIEEVKFDVTDFGISSIPIDKLIVNSAEDSAIKIVRAFLGKDEHVAEFIKINTAVALFALDKVSDFKEGYEYAKYLIENSVNKLNEIISLNGDLTKLKTIMVKSSG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: EPSG_BACSU
Sequence: MIVYAVNMGIVFIWSWFAKMCGGRDDSLATGYRPNKLLIWIPLASLVLVSGLRYRVGTDFQTYTLLYELAGDYQNVWQIFGFGTAKTATDPGFTALLWLMNFITEDPQIMYFTVAVVTYSFIMKTLADYGRPFELSVFLFLGTFHYYASFNGIRQYMVAAVLFWAIRYIISGNWKRYFLIVLVSSLFHSSALIMIPVYFIVRRKAWSPAIFGLSALFLGMTFLYQKFISVFVVVLENSSYSHYEKWLMTNTNGMNVIKIAVLVLPLFLAFCYKERLRSLWPQIDIVVNLCLLGFLFGLLATKDVIFARFNIYFGLYQMILVPYFVRIFDEKSNALIYIAIVVCYFLYSYLLMPVDSSVLPYRTIFSR
What is the function of this protein?
May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation.  EPS is responsible for the adhesion of chains of cells into bundles.  Required for biofilm maintenance.
What are the official names of this protein?
Transmembrane protein EpsG.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NIKR_SHIBS
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: UXUA_TOLAT
Sequence: MEQTWRWYGPNDPVSLSDVRQAGATGVVNALHHIPNGQVWPVEEILARKAIIEAAGLTWSVVESVPIHEDIKTQTGDYLKYIENYKQTLRNLAQCGIHTVCYNFMPVLDWTRTDLEYVMPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEVEQANARFAAMTDAEKARLTRNIIAGLPGAEEGYTIEQFRARLADYDGIDKAKLREHFAFFLKNIIPVAEQVGLRMAVHPDDPPRPILGLPRIVSTIEDMQWMVETVDSIANGFTMCTGSYGVRGDNDLVAMIKRFGNRIYFTHLRSTCREENPKTFHEAAHLGGDVDMYNVVKAILEEEYRRKQEGHPLLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELALKRAFFE
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: CSRA_SHEPA
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQSEKSGTPSEGGNF
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIFF_AMYMS
Sequence: MNVFDVETYLQRIGCGGETGVDLETLAKLQKSHLMAIPYSSLAYELRDAVNVVDLDEDDVFVTSIAEGQGGACYHLNRLFHRLLTELGYDVTPLAGSTAEGRETFGTDVEHMFNLVTLDGADWLVDVGYPGPTYVEPLAVSPAVQTQYGSQFRLVEQETGYALQRRGAVTRWSVVYTFTTQPRQWSDWKELEDNFRALVGDTTRTDTQETLCGRAFANGQVFLRQRRYLTVENGREQVRTITDDDEFRALVSRVLSGDHG
What is the function of this protein?
Catalyzes the release of the completed linear polyketide from the rif PKS by forming an intramolecular amide bond, in this way terminating polyketide assembly and forming the macrocyclic compound proansamycin X, an intermediate in the rifamycin B biosynthesis.
What are the official names of this protein?
Proansamycin X synthase, Rifamycin amide synthase.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
Protein: LEXA_BRUSI
Sequence: MLTRKQHELLLFIHERLKETGIPPSFDEMKEALDLASKSGIHRLITALEERGFIRRLPNRARALEVLRLPDSIAPGLSPQKKFAPSVIEGSLGKVASVQPVRPAPAPQNSEAPATVSVPVMGRIAAGVPISAIQNQTHMLSLPPEMIGAGEHYALEVKGDSMIDAGIFDGDTVIIKRGDTANPGEIVVALVDEEEATLKRFRREGASIALEAANPAYETRIFGPDRVHVQGKLVGLIRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: GLSA_PSE14
Sequence: MQDLLNEILDEVRPLLGQGKVADYIPALGGVRPDQLGIAVYGNDGQVFSAGDAETQFSIQSISKVFSLVQAIGHSGEDIWQRLGHEPSGQPFNSLVQLEFERGRPRNPFINAGALVICDINQARFAAPSLSMRDFVRRLCGNRAITSDSKVAESEYQHRSRNAAAAYLMKSFDNFHGDVEDVLRSYFHHCALSMNCIDLAKAFGFLANQGFCTHSGEQILTARQATQVNSIMATSGLYDEAGNFAYRVGLPGKSGVGGGIVAIVPERASVCVWSPELNAAGNSLVGMAALEKLSARIDWSVF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: GPMA_LACAC
Sequence: MSKLVLIRHGQSEWNLSNQFTGWVDVNLSEKGVEEAKKAGRLIKEHGLEFDQAYTSLLTRAIKTLHYALEESDQLWIPETKTWRLNERHYGALQGLNKKATAEKYGDEQVHIWRRSYDVLPPAIDDDNEFSQAHDRRYANLDPHIVPKAENLHVTLDRVMPFWEDNIAPDLLDGKNVIIAAHGNSLRALTKYIENISDDDIMDLEMKTGEPVVYTFDENLDVVNKEKLDD
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: BPT_CAUVC
Sequence: MTQHFPTRQLRFFLTAPTPCPYLPGREERKVFAHLPLSDGPIVNDSLTQVGFRRSQNIAYRPACETCRACQSARAPATEYILSRSERKILGRNDDLERHLVEAEATLEQFELLRRYLLTRHADGGMAEMTWPDYVAMVEDTAVRTHLIEYRRKSLDRGPGDLVACVLVDVLADGLSLVYSFYEPDQPRRSLGSFIILDHIVQAQQNALPYVYLGYWVPGSEKMAYKARFSPLEILKPGGWSLMSARERGARPPRGPGALKDACDLPLSDAQPADIEDLD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_SHEPW
Sequence: MNKSYFIGLMSGTSMDGVDAVLVKFSGDTPSLIAHHSEEIPAALLRNLQKLCLPGNDEINRLGHLDRAVGKLFAKAVNTLLDKAGVDKLAVIAIGSHGQTVRHMPNLEMGFTLQIGDPNTIAAETGIDVIADFRRKDIALGGQGAPLVPAFHQQVFATPEHKRIILNIGGIANITYLPGNTEAVTGFDTGPGNTLMDAWTQYHQDLPYDKDGAWAKTGTTDDKMLLHLLSHPYFSLAAPKSTGRELFNQAWLEQQLAEFNHLSDADIQSTLLDLTCFSIANDTLALSTMGEMYVCGGGAYNTELMCRLKQLLPHYKITTTAELGINPQWVEGIAFAWLAMRFHLGLPGNLPAVTGANRAAILGGKFSAL
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: F16PA_CAMJ8
Sequence: MQEVISYIQKAVLEISNALKFPDTSYSQNQNFTGDTQLKFDVLSDGIITKTLSQCSSIKAIISEEKDEILTLNERANFIVAYDPLDGSSLMDVNFAIGSIFAIYEEKASAKNLRAALYSMYGARLELVICKDQPKLYRLNANNEFIFIKDLKMNEKGKINATGGTQKFWEEKHAKFIKSLFDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGKTTNGKNHSLLELEFDKIHATTPCFFGSEYEISKLLKAYNE
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_AERPE
Sequence: MASRDSLGEVFRVSIFGESHGPGVGALVTGVPPGLEVDEAYINRELERRRPGGPYASPRREADRVEILSGVFRGRTTGAPILLFIRNVDVKPGFYEEFRYKPRPGHADYVAYERYLGHQDYRGGGIFSGRRTAALVAAGAIAKLVLARYGVRVYAYVKSIGGVEARVEPRDSEEFRRAIDRDPLKCPDPEASERMRRLVEEARREGDSLGSVVEAVAFNVPPGLGDPPLGGVDALLARAVMAIPAAKAVEFGEGFALAFMRGSEAHDSPRAVGGRIVHETNRSGGIVGGLTNGMPIVFRVAFKPPSSIPKPRRTVDLRSLGEAWVSGKGRHDPVIGPRAAPVVEAVTAIVLADLLLLREALLPEWVEDLRPWTRGEAGGD
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HAND2_MOUSE
Sequence: MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
What is the function of this protein?
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries.  Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway.  Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud.  Is involved in the development of branchial arches, which give rise to unique structures in the head and neck.  Binds DNA on E-box consensus sequence 5'-CANNTG-3'.
What are the official names of this protein?
Heart- and neural crest derivatives-expressed protein 2, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND, Helix-loop-helix transcription factor expressed in embryo and deciduum, Thing-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CFA69_MOUSE
Sequence: MSTAEASATTADAAEAGGRTKTGSPRTIPVFGVAIPDGEMQGIFKPMDLNRIIKVLEEEDKDVSEEKQLNYIKKLIHCYQNGFPLRDLAQIFKILSLCAEKIEKQPCFVEPASDIIKLCGLPFLKKKVSDEITYTEDTANSFALLGELMKIPSSALRIQICKCIVDFYHAEPLKKHIPGYQQVSSSYKIKMVEVGGLAKAMVQSALLLENQLVEKLWVLKVLQHLSTSGVNCTLMVKAQAASGICAHLNDPDPSGQLLFRSSEVLWNLLEKSSKEEIIQQLSNLECLLALKEVFKNLFVRGHSHYERQLRNDILVITTIIAQNPGAPMIECGFTRDLILFATFNEVKSQNPLVKSLKLFNCYEDFELKKLLFNIIVILCKDLATVQLLIDGKVILALFTYVKKPERLKIMEWSAAQYEELQLHAIATLSSVAPLLIEEYMSCHGNSRILAFLEWCGHEDSYFIHGNSFHGTGGRGNKFAQMRYTLRLLRAMVYLEDETVNKDLCERGVIHQLIEIFKTMMSRPAEKEEAIALEIQSDTLLILSGLCENYIQRKEMFGTEGVDIVLHVMKTDPKNLQRGLGYNVLLFSTLDSIWCCILGCYDSEDYFLEKEGIFLLLDILALNQKKFCNLILGIMVEFCDNPKTSAHVNAWRGKKDLTAASLLIKLWRKEEKELGVKRDRNGKIVDTKRPLFTSFQEEQKTMPLPANCPSIAVMDVAENIRAKIYAVLDKLDFENLPGLSAEDFVTLCIIHRYFDFKIGEIWNEVSEEIKLEKLRLVTTDEKSLNSIIAATENIGKMVASLQSEMIENQALQDVQNEQRVYAKIQATHKQREQANKSWENFLARTSNAKTLKKAKKLQEKAIESSRYTERPQNATFHQTVIKGLNTTVPSGRVVTVQSTPTRLLGGPLADTDIALKKLPIRGGALQRVKVKPPLNDPKKSIPT
What is the function of this protein?
Cilium- and flagellum-associated protein (PubMed:28495971, PubMed:29606301).  In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (PubMed:28495971).  Required for sperm flagellum assembly and stability (PubMed:29606301).
What are the official names of this protein?
Cilia- and flagella-associated protein 69.
What are the subcellular locations of this protein?
Cell projection, cilium. Cell projection, cilium, flagellum. Note=Localizes to the midpiece of the sperm flagellum.
Protein: AZOR_HYDCU
Sequence: MATVLRIDSSALSNGSHSKALADFFQTQWLEKHPTDSFQTLDLSQTPPPHLSEATIGAMFTPTEERSKEQTQQLALSTDYIEQLKKADVILISTPMYNFGIPSTLKAYLDHSLRVGETFVYTDKGPKGLLEGKKAIVVAASGGDYTQSPLDAMNFVTPYLKTALGFIGIEDVTLVEAPGMAGDEASINKSIKQAKQTLQNCL
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: CDGT2_PAEMA
Sequence: MKKQVKWLTSVSMSVGIALGAALPVWASPDTSVNNKLNFSTDTVYQIVTDRFVDGNSANNPTGAAFSSDHSNLKLYFGGDWQGITNKINDGYLTGMGITALWISQPVENITAVINYSGVNNTAYHGYWPRDFKKTNAAFGSFTDFSNLIAAAHSHNIKVVMDFAPNHTNPASSTDPSFAENGALYNNGTLLGKYSNDTAGLFHHNGGTDFSTTESGIYKNLYDLADINQNNNTIDSYLKESIQLWLNLGVDGIRFDAVKHMPQGWQKSYVSSIYSSANPVFTFGEWFLGPDEMTQDNINFANQSGMHLLDFAFAQEIREVFRDKSETMTDLNSVISSTGSSYNYINNMVTFIDNHDMDRFQQAGASTRPTEQALAVTLTSRGVPAIYYGTEQYMTGNGDPNNRGMMTGFDTNKTAYKVIKALAPLRKSNPALAYGSTTQRWVNSDVYVYERKFGSNVALVAVNRSSTTAYPISGALTALPNGTYTDVLGGLLNGNSITVNGGTVSNFTLAAGGTAVWQYTTTESSPIIGNVGPTMGKPGNTITIDGRGFGTTKNKVTFGTTAVTGANIVSWEDTEIKVKVPNVAAGNTAVTVTNAAGTTSAAFNNFNVLTADQVTVRFKVNNATTALGQNVYLTGNVAELGNWTAANAIGPMYNQVEASYPTWYFDVSVPANTALQFKFIKVNGSTVTWEGGNNHTFTSPSSGVATVTVDWQN
What are the official names of this protein?
Cyclomaltodextrin glucanotransferase, Cyclodextrin-glycosyltransferase, CGTase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIG_RALPJ
Sequence: MTTTNLSAVADPLRLYDETFASRLLLGTARYPSPQSLEDAVRVSNPAMLTVALRRQSAGSPEGGAGFWKMLRELGVPVLPNTAGCYSADEAYTLAQMSRELFETDWIKLEVIGDDYTLQPDTLALPAAAERLIRDGFKVLPYCTEDLVLCRRLLDVGCQALMPWAAPIGTGRGPTNPYGLRLLRERLPNVPLIVDAGLGVPSHATQVMEWGYDAVLLNTAVAQAGDPVAMAQAFAMATQAGRLARLSGPMPERDVAQASTPVVGLPFWHAEEKQA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_RICPU
Sequence: MSNSNIHTTAVIAEGTKLGNNVKIGPYCIIGPKVVLHDNVELKSHVVIEGITEIGENTVIYPFASIGQPPQILKYANERSSTIIGSNNTIREYVTVQAGSQGGGMMTRVGNNNLFMVGVHIGHDCKIGNNVVFANYVSLAGHIGVGDYAIIGGLSAVHQYARIGEYSMIGGLSPVGADVIPFGLVSSKRAVLEGLNLIGMNRKGFDKVKSLSALKAIEEIFSGEGNFAERIKQVAEKYNNNSIVIQIIDFLNQDSSRAFCRFEK
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPZ_PECCP
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPELANTLAARNISAAVSIDVRNMPESPEIFEHAMEQLPPSFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDEESDLLEPLRSRADLIIDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVASFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYVAEQLADYFRSRGKNVQSRHRTLEKRKPS
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: HTF_EUBSB
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, EubSp-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB_LACLS
Sequence: MTYNQPNNQGFYGQFGGQFVPETLMTAVKELEVAYEDSKKDPVFQAELKELLKDYVGRENPLYFAKRLTEYAGGAKIYLKREDLNHTGAHKINNALGQVLLAKKMGKNKVIAETGAGQHGVATATAAALFGMECTIYMGEEDVKRQSLNVFRMELLGAKVHSVTDGSRVLKDAVNAALRAWVAQVEDTHYVMGSVLGPHPFPQIVRDYQAVIGQEARAQFLEKENKLPDALVACVGGGSNSMGLFYPFVNDESVEMYGVEAAGLGIDTPHHAATITKGRPGVLHGTLMDVLQDENGQILEAFSISAGLDYPGIGPEHSYFNAVGRAKYVDITDEEALEGFKILSRTEGIIPALESSHAIAYAVKLAKELGSEKTMIVCLSGRGDKDVVQVKERLEAEKEVK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: TRUB_MYCUA
Sequence: MSRQNAGPGFGPGIVVVDKPGAMTSHDVVGRCRRIFGTRRLGHAGTLDPMATGVLVIGIERATKILGLLIATSKSYAATIRLGQTTSTEDAEGEPLASVSAEHVAPEAIAAAILDLTGDIRQVPSAVSAIKVDGRRAYQLAREGQTVELAARPVRIDRFELMDLRRGADVIDIDVEVDCSSGTYIRALARDLGAALDVGGHLTSLRRTRVSHFDLSQAASLDELAERPALSLTLDQACLLMFPRRDLTVDESQSVGNGRPLEPAGIDGIYAASDADGRVIALLRDEGRRTKSVVVIRPATM
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.