PharMolix/UniProtQA huggingface dataset:
Protein: PUR5_ACTP2
Sequence: MSNTQLSYKDAGVDIHAGNELVERIKGDVKRTRRPEVMGGLGGFGALCALPTKYKEPILVSGTDGVGTKLRLAIDLNKHDTIGQDLVAMCVNDLVVQGAEPLFFLDYYATGKLEVDVAADVIKGIADGCEISGCALVGGETAEMPGMYHEGDYDLAGFCVGVVEKSEIIDGSAVKAGDVLLALASSGPHSNGYSLIRKVIEVSGANPATDTLEGKPLSEHLLAPTKIYVKSVLQLIKQADVHAIAHLTGGGFWENIPRVLPATAKAVIDEKSWEWPAAFKWLQEKGNISRYEMYRTFNCGVGMVIALPEKDIETALAVLKQAGENAWVIGKIENLGEGSEQVEII
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNNC2_ANGAN
Sequence: PTDAQTDARSFLSEEMIAEFKAAFDMFDTDGGGDISTKELGTVMRMLGQNPTREELDAIIEEVDEDGSGTIDFEEFLVMMVRQLKEDQAGKSEEELAEFFRVFDKNGDGFIDREEFGEILRSSGEPVSEEEIDELMADGDKNNDGKIDFDEWLKMMENIQ
What is the function of this protein?
Troponin is the central regulatory protein of striated muscle contraction.  Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding EF-hand for tropomyosin and Tn-C.  The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
What are the official names of this protein?
Troponin C, skeletal muscle, TNC.
What is the protein family that this protein belongs to?
Belongs to the troponin C family.
Protein: PLS1_PITOR
Sequence: FLSLIPHAINAVSTLVHHSG
What is the function of this protein?
Has antiprotozoal activity against T. cruzi.
What are the official names of this protein?
Phylloseptin-O1, PLS-O1, Phylloseptin-4, PS-4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YHR1_HCMVA
Sequence: LQRRQGQNPQPDPSLSDTLSRTTGVTDRSRAKYRESNATPSPRSQAPRKVLRFFTVVRDVDLPRSENRPSVRTGAQKQPAVRATERFTAPAADSYRRDVRAAGTSALPASPPRARPSLYSPTPRPTRLWRANRTAGALQVDDRHSRVPDREEPSST
What are the official names of this protein?
Uncharacterized protein HHRF1.
Protein: ADML_MOUSE
Sequence: MKLVSITLMLLGSLAFLGADTAGPDTPSQFRKKWNKWALSRGKRELQASSSYPTGLADETTVPTQTLDPFLDEQNTTGPLQASNQSEAHIRVKRYRQSMNQGSRSNGCRFGTCTFQKLAHQIYQLTDKDKDGMAPRNKISPQGYGRRRRRSLLEVLRSRTVESSQEQTHTAPGPWAHISRLFRI
What is the function of this protein?
AM and PAMP are potent hypotensive and vasodilatator agents.
What are the official names of this protein?
Pro-adrenomedullin.
What is the protein family that this protein belongs to?
Belongs to the adrenomedullin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ICP27_ELHVK
Sequence: MESGRRPIVPYTGPVPDVKKLLTENRFARLADLVVPLEVLGETDFVRHIHAQFENLSRDEMDELVLARTVAINSAPSLFSILLMAEETCSYFSAIDRLDIPVNPYDPYASTLSALKHATFSKLNVAKLSCMMSNGERPPSASSDYDFLKKIASGNGATVKSFSRSSESTVAPFPAATKQVPDISDIREFDFETFRHPFQKVICFLATIEKVISEIKGHRAPGCIAGGPINPKDRSRYIRDYDKQGIMRRYKDGCIIGLVKQGFCEHACNDNACRRRCKFALSVPYNLGMVFCPPTENSSVEDMDAYFERNRCPTRNGSFDDSRSATSGDGSSCSSAHKVTTPTDGVMMPEFPFSDQTDTSNNGTVRFSERRVSSSSKHRRRSNKHISPLDRPNDYHYQKNQPTPSDEKRYYHGSGSSSTEAVSTASAPLTGSAANQHPQHCGGQSGSDTGVISRGEGRHHGSHNGIPDFVSRSPVTTPPEVFSPERRSSEERSSSDQRRKSPLSRSASATSGGSKRRSFVDSPPRHESEDEDEDSDSSSSEAQKDRFKKRSGSRSNTPPSSPSKPDSAPAASASPGGDGGNDSDDGATEKGVTSNAKESVRVSERFETGDKSPTFIETEDESDDEDDQMSITSYDHSESSSAESGSETDGEDGESDMTL
What is the function of this protein?
Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs.
What are the official names of this protein?
mRNA export factor ICP27 homolog.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 ICP27 protein family.
What are the subcellular locations of this protein?
Virion tegument. Virion. Host nucleus. Host cytoplasm. Note=Shuttles between host nucleus and cytoplasm.
Protein: MOEA2_MYCTU
Sequence: MRSVQEHQRVVAEMMRACRPITVPLTQAQGLVLGGDVVAPLSLPVFDNSAMDGYAVRAEDTSGATPQNPVMLPVAEDIPAGRADMLTLQPVTAHRIMTGAPVPTGATAIVPVEATDGGVDSVAIRQQATPGKHIRRSGEDVAAGTTVLHNGQIVTPAVLGLAAALGLAELPVLPRQRVLVISTGSELASPGTPLQPGQIYESNSIMLAAAVRDAGAAVVATATAGDDVAQFGAILDRYAVDADLIITSGGVSAGAYEVVKDAFGSADYRGGDHGVEFVKVAMQPGMPQGVGRVAGTPIVTLPGNPVSALVSFEVFIRPPLRMAMGLPDPYRPHRSAVLTASLTSPRGKRQFRRAILDHQAGTVISYGPPASHHLRWLASANGLLDIPEDVVEVAAGTQLQVWDLT
What is the function of this protein?
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
What are the official names of this protein?
Molybdopterin molybdenumtransferase 2, MPT Mo-transferase 2.
What is the protein family that this protein belongs to?
Belongs to the MoeA family.
Protein: MCM_CERS4
Sequence: MTEDLDAWRKLAEKELKGKSPDSLTWNTLEGIPVKPLYTRADLAGMEHLDGLPGVAPFTRGVRATMYAGRPWTIRQYAGFSTAEASNAFYRKALAAGQQGVSVAFDLATHRGYDSDHPRVVGDVGKAGVAIDSIEDMKILFNGIPLEKISVSMTMNGAVIPILANFIVTGEEQGVPRAALSGTIQNDILKEFMVRNTYIYPPEPSMRIIADIIEYTSKEMPKFNSISISGYHMQEAGANLVQELAYTLADGREYVRAALARGMNVDDFAGRLSFFFAIGMNFFMEAAKLRAARLLWHRIMSEFAPKKPGSLMLRTHCQTSGVSLQEQDPYNNVIRTAYEAMSAALGGTQSLHTNALDEAIALPTEFSARIARNTQIILQEETGVTRVVDPLAGSYYVESLTAELAEKAWALIEEVEAMGGMTKAVASGMPKLRIEESAARRQAAIDRGEDVIVGVNKYRLAKEDPIEILDIDNVAVRDAQIARLEKMRATRDEAACQAALDELTRRAAEGGNLLEAAVDASRARASVGEISMAMEKVFGRHRAEVKTLSGVYGAAYEGDDGFAQIQRDVESFAEEEGRRPRMLVVKMGQDGHDRGAKVIATAFADIGFDVDVGTLFQTPEEAAQDAIDNDVHVVGISSLAAGHKTLAPKLIEALKEKGAGEILVICGGVIPQQDYDFLQQAGVKAIFGPGTNIPSAAKHILDLIREARS
What is the function of this protein?
Radical enzyme that catalyzes the transformation of (2R)-methylmalonyl-CoA to succinyl-CoA.  Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for R. sphaeroides growth on acetate as sole carbon source.
What are the official names of this protein?
Methylmalonyl-CoA mutase, MCM.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA mutase family.
Protein: DEOD_BACSU
Sequence: MSVHIGAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYKGKKISVQGTGMGVPSISIYVNELIQSYDVQNLIRVGSCGAIRKDVKVRDVILAMTSSTDSQMNRVAFGSVDFAPCADFELLKNAYDAAKDKGVPVTVGSVFTADQFYNDDSQIEKLAKYGVLGVEMETTALYTLAAKHGRKALSILTVSDHVLTGEETTAEERQTTFHDMIEVALHSVSQ
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP, Purine nucleoside phosphorylase II, PU-NPase II.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: HSP71_PICAN
Sequence: MSKAVGIDLGTTYSCVAHFVNDRVEIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRKFDDPEVQNDIKHFPFKVVEKGGKPHIQVEFKGETKVFTPEEISSMVLTKMKETAESYMGGKVTDAVITVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDKKEQGKGEQNILIFDLGGGTFDVSLLSIDEGIFEVKATAGDTHLGGEDFDNRLVNHFANEFKRKYKKDLTTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLYEGIDFYTSITRARFEELCQDLFRSTLDPVEKVMRDGKLDKSQVAEIVLVGGSTRIPKIQKLVSDFFNGKEPNKSINPDEAVAYGAAVQAAILTGDTSSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNTTIPTKKSEIFSTYSDNQPGVLIQVYEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSQKITITNDKGRLSKEEIDRMVAEAEKYKEEDEKEAARIAAKNGLESYAYSLKQTASEKQFEEKVDASKRESLNKAIEETISWLDNNQSATTDEYEDKRKELEGIANDALKDLYAAGGVPGGAAPGGFPGAGGAAPGADQGPSVEEVD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Heat shock protein 70 1, HSP72.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15E_SULTO
Sequence: MTSSMYNYIEQTWQSDEWKKVLRQRLIEWRKSPAVERIDKPTRLNRARAIGYKAKQGFVVVRVRVRRGGLNKPRPNSGRRPKRMGVYGYSPAKGYRWIAEEKAARKFPNLEVLGSYYVGEDGMYKYYEIIMVDPNHPVIKSDPNLKWLQDPANRKRVFRGLTSAGKKARGLLKSRGLKGTVKHKWKKKEKEREQKKRHEATKYYRLQNYDKLPGK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: GOGA4_HUMAN
Sequence: MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNRESGDTQSFAQKLQLRVPSVESLFRSPIKESLFRSSSKESLVRTSSRESLNRLDLDSSTASFDPPSDMDSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGTPYKGGNLYHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAKVITTVLKFPDDQTQKILEREDARLMFTSPRSGIF
What is the function of this protein?
Involved in vesicular trafficking at the Golgi apparatus level.  May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1.  Involved in endosome-to-Golgi trafficking (PubMed:29084197).
What are the official names of this protein?
Golgin subfamily A member 4, 256 kDa golgin, Golgin-245, Protein 72.1, Trans-Golgi p230.
Protein: PTFB_HALVD
Sequence: MKLVAVTSCPTGIAHSQMAAENLLQAGERLGHDIDVEVQGAMGTQDELASDAIAEADAVIITSDTSVSRDRFDGKLVLKGTVKDGVNNAEAVVQKAVELAEAGKTGSVTFGSGDDGEDADVGADDSSDDADAAESDEPVRRGGDPEKGLFARLKKLFS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II PtfABC PTS system is involved in fructose transport.
What are the official names of this protein?
PTS system fructose-specific EIIB component, EIIB-Fru, Fructose-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_SHISS
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPD_LIGS1
Sequence: MKLDNETIVHRYGKALFELAEEMKIRNKFHSELQEYKKVLQNEPQLKVFMSSNQISPEAKLKIMEILKKDSSKLMTNLLDMLYDYGRITSLEGIIDEFDRLNDEFEKTVRASVITAIELDEERKQKLASSFANVVGAKKVIIDPIVDPGIIGGVILKSESYIYDGSIKTKIARIKRLLLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FETP_CUPNH
Sequence: MARMVQCIKLNKEAEGLDFPPLPGELGKKIWQSVSKEAWAGWLKHQTMLINENRLNMADARARQYLLKQTEKYFFGEGADQAQGYVPPQS
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: PRM5_YEAS8
Sequence: MTVITIAKRGLPKLTTSTSSTTTASSSSTITSVASSSSSLPLLSNSTSSSIIPSITPPSRNGNPYILDSGDMPNGTVFIVVGGIAGVIFLAILLWWVITTYSSHRLTRSVQDYESKMFSAQHTQFYGDSPYMDYPAKENFQDQVHISESDISPGNKDESVKDALVSHTNNEKPFLSNFERPLSSLVSESNRNSLFISPTGDILYKTRLSKLYQESPRLLQKPVIMTSDNVSTNSLVSTISSSSASSLDNGNEKEVGEDIRKPAKIASSPSRKLLNSPESDGSVNRNHSKGNLLVVQSKRKPTPSTYLEHMLEGKEQDE
What are the official names of this protein?
Pheromone-regulated membrane protein 5.
What is the protein family that this protein belongs to?
Belongs to the PRM5 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SSRP_AGRFC
Sequence: MAPKGSQRVVNKIVAENRKARFNYEIIDTYEAGLVLTGTEVKSLREGKANIAESYASDEGDEIWLINSHLPEYLQANRFNHEPRRRRKLLLNKREINRLRAGINRDGMTLVPLKVYFNEKGRAKLELALAKGKKLHDKRETEKERDWNRQKSRLLKGNSQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GUF1_AJECN
Sequence: MRGCLQSVKWLTSALRPSQSLASSTRYPRRLLSTSAPRNAQVRKPASEVEQRIAAIPIERFRNFCIVAHVDHGKSTLSDRLLELTGTIEAGANKQVLDKLDVERERGITVKAQTCSMLYNHQGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGIQAQTVANFYLAFAEGLKLVPVINKVDLPSADPQRALDQMKNTFELDPESAVLVSAKTGLNVSQLLPTVIEQIPAPVGDRTKPLRMLLVDSWYSTYKGVILLVRLFDGEIRVGDQVVSFATGLKYTVGEVGIMYPWQTAQSVLRAGQVGYIYFNPAMKRSQEAKVGDTYTKVGSEKLVQPLPGFEEPKAMVFVAAYPVDASDFPHLEDSINQLILNDRSVTLQKESSEALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPTVPFKVIWKDGKEEIITNPALFPEEDTLRAKVTELQEPFVLATLTFPEEYLGRVIELCESNRGEQKSLEFFTSTQVILKYELPLAQLVDDFFGKLKGSTKGYASLDYEESGWRRSNISKLQLLVNKVPVDAVSRVVHSSQVQRLGRLWVSKFKEHVDRQMFEVVIQAAAGRNVVARESIKPFRKDVLQKLHAADVTRRKKLLEKQKEGRKKLKAVGNVVIEHKAFQAFLAK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MNS1B_EMENI
Sequence: MRTLLALAALAGFAAARVPAYAITRPVMRSDSRADAVKEAFSHAWDGYYNYAFPHDELHPISNGYGDSRNHWGASAVDALSTAIMMRNATIVNQILDHIAAVDYSKTNAMVSLFETTIRYLAGMISGYDLLKGPAAGLVDDSRVDVLLEQSQNLAEVLKFAFDTPSGVPYNMINITSGGNDGATTNGLAVTGTLVLEWTRLSDLTGNDEYARLSQRAEDYLLHPEPAQYEPFPGLIGSAVNIADGKLANGHISWNGGADSYYEYLIKMYVYDPERFGLYRDRWVAAAESSINHLASHPSTRPDVTFLATYNEEHQLGLTSQHLTCFDGGSFLLGGTLLDRQDFVDFGLDLVAGCHETYNSTLTGIGPEQFSWDPNGVPDSQKELFERAGFYINSGQYILRPEVIESFYYAWRVTGDGTYREWVWNAFTNINKYCRTATGFAGLENVNAANGGGRIDNQESFMFAEVLKYSFLTFAPEDDWQVQKGSGNTFVYNTEAHPFKVYTPQ
What is the function of this protein?
Involved in the maturation of Asn-linked oligosaccharides.  Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
What are the official names of this protein?
Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B, Class I alpha-mannosidase 1B, Man(9)-alpha-mannosidase 1B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle lumen.
Protein: RBN_ECOLU
Sequence: MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQHQLLHTTFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVETALRISGSWIDYPLEIVEIGAGEILDDGLRKVTAYPLEHPLECYGYRIEEHDKPGALNAQALKAAGVPPGPLFQALKAGKTIMLEDGRQINGADYLAAPVPGKALAIFGDTGPCDAALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYDDKGCQHLLRECRSIFPATELANDFTVFNV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: ARGR_VIBC1
Sequence: MRNSEKQDNLVRAFKALLKEESFGSQGEIVDALKQQGFESINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTVSSSLRELVLDIDHNAALVVIHTGPGAAQLIARLLDSLGKSEGILGVVAGDDTIFITPTMPVSTEQLFKSVCELFEYTG
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PT225_ARATH
Sequence: MGKGRALSDGVIKKIILSYTYVAIWIFLSFTVIVYNKYILDKKMYNWPFPITLTMIHMGFCSSLAVILIKVFKVVEPVSMSRETYLRSVVPIGALYSLSLWLSNSAYIYLSVSFIQMLKALMPVAVYSIGVLLKKETFKSQTMTNMLSISFGVAIAAYGEAKFDGWGVFLQLGAVAFEATRLVLIQILLTSKGINLNPITSLYYVAPCCLVFLSVPWIFVEFPVLRDTSSFHFDFVIFGTNSVCAFALNLAVFLLVGKTSALTMNVAGVVKDWLLIAFSWSVIKDTVTPINLFGYGLAFLGVGYYNHCKLQALKAKDAQKKVQASDDEAGKLLEERESEAKRNETQD
What are the official names of this protein?
Probable sugar phosphate/phosphate translocator At2g25520.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GPR18_RAT
Sequence: MAIPSNRDQLALSNGSHPEEYKIAALVFYSCIFLIGLLVNVTALWVFSCTTKKRTTVTIYMMNVALLDLVFILSLPFRMFYYAKGEWPFGDYFCHILGALVVFYPSLALWLLALISADRYMAIVQPKYAKELKNTGKAVLACVGVWIMTLTTTVPLLLLDEDPDKASSPATCLKISDIIHLKAVNVLNFTRLIFFFLIPLFIMIGCYVVIIHSLLRGQTSKLKPKVKEKSIRIIVTLLLQVLACFVPFHICFALLMLQGEENSYSPWGAFTTFLMNLSTCLDVVLYYIVSKQFQARVISVMLYRNYLRSVRRKSVRSGSLRSLSNMNSEML
What is the function of this protein?
Receptor for endocannabinoid N-arachidonyl glycine (NAGly) (PubMed:24431468).  However, conflicting results about the role of NAGly as an agonist are reported (By similarity).  Can also be activated by plant-derived and synthetic cannabinoid agonists (PubMed:24431468).  The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase (By similarity).  May contribute to regulation of the immune system (By similarity).  Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs) in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant (By similarity).  Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure (PubMed:24431468).  Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis (By similarity).
What are the official names of this protein?
N-arachidonyl glycine receptor, NAGly receptor, G-protein coupled receptor 18.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
Protein: RLMI_SHEAM
Sequence: MSIRIKLKPGREKSLDRRHPWVFSSGVHNIKGKPLRGETVDVVAHDGRWLGRGAWSDASQIQVRVWTFDKEEAIDRDFFARRIARAQAGREALIREKGLTGYRLVGAESDGLPGITIDRYANVLVCQLLSAGADYWRETLVSVLAEQFPECAIYERSDVDSRKKEGLPLVTGLLHGELPAMPLIIEENGIKIAVDVEKGHKTGFYLDQRDNRAMAGRFVEGKSVLNCFCYTGTFGLYAAKAGAASIENVDVSTLALDTARHNMAINGLNDDHVTYSEADVFKLLRQYRDEGKTFDVIVLDPPKFADNKAQLNGACRGYKDINMIAMQLLKPGGTLLTFSCSGLMPADLFQKIVADAALDAGRDAQFIERLSQASDHPIGAAFPEGFYLKGLVARVW
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2A_YEAST
Sequence: MSTSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDETVWEGIEPPSKDVLDELKNYISKRLTPQAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNITMPPKAVTATEDAELQALLESKELDNRSDSEDDEDESDDE
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.  This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex.  Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.