PharMolix/UniProtQA huggingface dataset:
Protein: PORD_PSEAE
Sequence: MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQGTVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMQPTAPVFAAGGSRLFPQTATGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNSNYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSIFLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYVVQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL
What is the function of this protein?
Porin with a specificity for basic amino acids.  Also possesses serine protease activity.
What are the official names of this protein?
Porin D, Imipenem/basic amino acid-specific outer membrane pore, Outer membrane protein D2.
What is the protein family that this protein belongs to?
Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: FETP_FRATM
Sequence: MTKVFCKKYHQELDAIPFQPLPGELGKKIHNEISNKAWQAWLAHQTILINEYRLNLIETKAKEFLKEEMHKFLFEGKEEKPEQFSEI
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: FOLD_POLAQ
Sequence: MPAQLLDGNALSKKLRAEIAARAAIVTAKGVRPGLAVIVVGDNPASQVYVRNKVKACEDVGFHSVLEPYPAELGEEELLARIATLNADPAIHGILVQLPLPEHIAAERVLEAIAPEKDVDGFHVSNAGALMVGKPEFIPCTPYGCMKLLESIEYPIRGARAVIVGASNIVGKPMAMLLLQAGATVTICNSKTRDLAHHTKDADILVVATGKPKMVSGDMIKNGAVVIDVGINRLPDGKLCGDVDFDAAKYVAGWITPVPGGVGPMTITMLLMNTLEAAEKASKP
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PERX_NICSY
Sequence: MNTPTQSFRAKAAIFSLLLLSCMQCHAQLSATFYDNTCPNALNTIRTSVRQAISSERRMAASLIRLHFHDCFVQGCDASILLDETPSIESEKTALPNLGSARGFGIIEDAKREVEKICPGVVSCADILTVAARDASAAVGGPSWTVKLGRRDSTTASKTLAETDLPGPFDPLNRLISSFASKGLSTRDMVALSGAHTIGQAQCFLFRDRIYSNGTDIDAGFASTRRRQCPQEGENGNLAPLDLVTPNQFDNNYFKNLIQKKGLLQSDQVLFNGGSTDNIVSEYSNSARAFSSDFAAAMIKMGDISPLSGQNGIIRKVCGSVN
What is the function of this protein?
Plays an integral role in secondary cell wall biosynthesis by the polymerization of cinnamyl alcohols into lignin and by forming rigid cross-links between cellulose, pectin, hydroxy-proline-rich glycoproteins, and lignin.
What are the official names of this protein?
Lignin-forming anionic peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTSA_STRMT
Sequence: MKKLGTLFVLFLSVIVLVACASGKKDAASGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFSKLVENAKKTENKDYFAVSEGVDVIYLEGKNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNNIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYNMMKYNLDKIAEGLAK
What is the function of this protein?
Part of an ATP-driven transport system for manganese.  Also acts as an adhesin which is involved on adherence to extracellular matrix.  It is an important factor in pathogenesis and infection (By similarity).
What are the official names of this protein?
Manganese ABC transporter substrate-binding lipoprotein, Pneumococcal surface adhesin A.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: METE_THEKO
Sequence: MELPILPTSIIGSYPKPRWLLRMYNLRELGRLPEEDFREAVRDASVAVLREHERAGIDIPWDGEMGRSEMTEYFTAKIAGFKFYGPIRVWGNAYFNKAAAVSKLEYREPLVLDEFRWVKENTTREIIKVPITGPYTIAEWSFNEYYSSKEELAFDLAKILNKEFKLLEKEGATFIQIDEPAMLNHPDEVSIAVEAINRAVKGVKVKFGLHVCYSNYYLLADYFDDIKVSQFALEAANRNFRDLDYLKKLTHQELGFGVVDVHNPRVESPEEVAKAIRKVMEYIEPERLYINPDCGLKLLDRRIAYQKLVNMVKGVEIVRRELAREGKTSIPFRREV
What is the function of this protein?
Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation.  The physiological methyl donor is unknown.
What are the official names of this protein?
Methionine synthase, Homocysteine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal MetE family.
Protein: RL34_BORBZ
Sequence: MKRTYQPSRVKRNRKFGFRARMKTKGGRLILSRRRAKGRMKLTVSDEKKKY
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL37A_METVS
Sequence: MVEFSHTKKIGSAGRFGPRYGRKIRVRLRDVEIKQNKEYKCPVCAFPKLKRAGTSIWVCDKCGAKIAGGAYTPETGAGKVVTKAIRRVIESKSREI
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: VP3_CAVC1
Sequence: MNALQEDTPPGPSTVFRPPTSSRPLETPHCREIRIGIAGITITLSLCGCANARAPTLRSATADNSESTGFKNVPDLRTDQPKPPSKKRSCDPSEYRVSELKESLITTTPSRPRTAKRRIRL
What is the function of this protein?
May act as transcriptional regulator.  Induces apoptosis in infected cells.  Element of infectious replication cycle.
What are the official names of this protein?
Apoptin.
What is the protein family that this protein belongs to?
Belongs to the gyrovirus apoptin family.
What are the subcellular locations of this protein?
Host nucleus. Note=Host nucleus of infected cells.
Protein: TXP3_BRAAI
Sequence: MRSLTLAAVLACSLLLVFHTSAAEEHEAQEGYLMNPGDTDTALATVDDERILECVFSCDIEKEGKPCKPKGEKKCTGGWKCKIKLCLKI
What is the function of this protein?
Inhibits voltage-gated calcium channels (Cav) in rat cerebellar granule cells (By similarity).  Has insecticidal activity (By similarity).
What are the official names of this protein?
Omega-theraphotoxin-Ba1c, Omega-TRTX-Ba1c, Venom peptide Ba3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 06 (TXP1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPD_BORPA
Sequence: MAELSTVARPYAEALFGAARDDKAGLAVWADLVSEMAQVAANPDVREAMADPRLDDKQRSEVFTGLIKSQLPQAARNFIELLVKNDRLLLLPVIATQFVALKNRHEGTAQAEITSAFELSDAQVKELIAALELKFGLKLKPHVSVDQELIGGVRVAVGDQVLDTSVKAQLARLRDTLAA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FRSA_YERPP
Sequence: MAQANLSEILFKPKFKHPETSTLVRRTHCNHVVNIHSALDGDTANHWYRMINRLMWTWRGIDPLEIEEVLSRIACSKAEHSNNELLDTVVGYRNGNWIYEWANQGMMWQQKAMEETDPGSAGQFWLNAANLYSIASYPHLKGDELSEQAEVLSNRAYEEAAKYLPYTLKELTFPISDGGSLSGFLHMPTVGSAPFPTVLMCGGLDTLQSDYHRLFRDYLEPKGIAMLTIDLPSVGASSRWKLTQDTSYLHQQVLQALADVPWVDHQRVSVFGFRFGANVAVRLGYLEPQRVRAVACLGPIVHHLLCNSDSLRKVPDMYMDVMASRLGMADSTDETLNTEMNRYSLKTQGLLGRRCQTPMLAGFWENDPFSPKEEAKLICSSSADGKLLAIPSKPLYENFHRALLQTSEWLEDKMR
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: EIF3C_DANRE
Sequence: MSRFFATGSDSESEESSSADEITPKAAGTTLRQQALLLSDDEEDTKRVVRSAKDKRFEELTNLIKTIRNAIKIRGISKCLEEFEQLCRAFVKSKTIVDKEGVPKFYIRLLADLEDYLNQLWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFETEIASYKENPEQSADEEEEKDDIGSGSSESDDDDDDDITAKSFMKKKPQEEEKKAPEASKFLKGAADEESESDDDEDSEDWASDSVGSDSESEDNDGTAASLAVVFLKKDVGEKASDRKKDDRRRRHKKKERIEEEAEEEGEAEEGGWEKVKGGVPLVKEKPKMFAKGTEINTGVVVKKLSEILQARGKKGTDRAAQIELLHALAGIAAENNLGEGILVKIKFNIIASLYDYNPNLAAFMKADMWKKCLDCIDELLDILFNNNNIFIGENIAEDSENLAISDQPFRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVDNLKDEGRVCGIIDRLLQYLETKGSTEEVCRVYLRRIMHTYYKFDYKAHRRSLGLQGETKSEQDQEESEGDDSAIIMDRLCKFIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGMIKDAHNALLDIQSSGRAKELLGQGLLMRNMQERNAEQEKIEKRRQVPFHMHINLELLECVYLVSAMLLEIPYMAAHEFDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWRTCHSFIINEKMNSKVWDLFPEAKCVREMLVRKIQEESLRTYLFTYSSVYDSISMETLSEMFELELPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTSLQNMALQLAEKLGGLVENNERVFDLKQGVYGGYFNRDQKGGYQQKQGYQRGDQKGGYQQKQNYQRGGYRNQNQSSY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATB_SHEFN
Sequence: MFDGIGFMELLLIGILGLVVLGPERLPVAVRSLTGWIRALKRMANSVKDELEQELKIDQLHADLKKAESKGLANLSPELQESIDQLKKAAESVNRPYKVEDTSPVAPKASPDESPSVVEAKSSEATSENSSTPK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS4_BAUCH
Sequence: MARYLGPKLKMSRRENIDLFLKSGVRAIDSKCKIEQPPGQHGARKPRLSDYGLQLREKQKVRRIYGILERQFRNYYQEAARLKGNTGESLLQLLESRLDNVVYRMGFGATRAESRQLVSHKAIMVNNHIVNIASYQVAINDKISIRDKAKKQSRIRASLELAEQREKPTWLEVDIVKMEGIFKKIPERIHLSAHINEHMIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PYRG_CAMJR
Sequence: MKQTKYIFVTGGVLSSLGKGIAAASIATLLKNSGLKVSILKADPYINVDPGTMSPFEHGEVFVTDDGAETDLDLGHYERFLDESLSQDNNFTTGRVYQSVIEKERRGEYLGKTIQVIPHIVGEIKDRIKKAGEGKDILIVEIGGTVGDIEGLPFLEAIRALRLEVGKNNAMNIHLTLVPFIKAAGELKTKPTQHSVGELRRIGISPDMIICRSEKALDRDLKDKIAISCGVEKNCVIESVDAASIYQIPLNFLKQDILSPIAEILDLKNLKPNMENWDSLVKRVIAPSNEVKIAFVGKYVDLKESYKSLTEAIIHAGAALDTKVELKWVDSEKLENMESSEVFKDVSGILVAGGFGYRGVEGKIKAIQYARENKIPFLGICLGMQLALVEFARNVLKLKDANSSEFNEKCQNPVVYLIDEFMDTNGEKQIRTAKTPLGGTMRLGAYKCDIKEKSLLAKVYNEVKSVKERHRHRYEANPKYRADFEKHGLIVSGESKGLIEAVELNCHPFFLAVQFHPEFTSRLEHVNPVICSFIKAAINYEDN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PANCY_PROM3
Sequence: MGALHRAHGQLIKSVQGFGSLQPAAVLVSVFVNPLQFGPAEDFDSYPRDLEADCELASRSGASALWAPSVDQVFPGGASSQFRIQVPSHLQAHLCGAIRPGHFDGVVTVVARLLALVRPEVLVLGEKDWQQLVILRHLVAQLGLPVRVHGVATVRDDDGLACSSRNRYLMTQQRQQALALPQLLARAARESQDGRAVDLAGLRCAWEQLGLEVEYVETVDAFNLQPLHAGRKLCLLAAAVRCGETRLIDHTFLMSRQPIVAIDGPAGAGKSTVTRAFAERLGLLYLDTGAMYRAVTWLTQQHDVDPHDPVAVKTILENLELELEPSQSGPQKVRINGHDVTEAIRSPEVTSSVSVVAAHGCVRKALTAQQQRMGVRGGLVAEGRDIGTAVFPDAELKVFLTASPAERARRRALDLDNRGFPVPDLAELETQIEERDRMDSTREVAPLRQAEDATELISDGMSIEEVIETLIDLFRVQVPEEVWPTPGS
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_CLOTE
Sequence: MNITIISVGKLKEKYLKLAVEEYSKRLSRYCKLNIIEVTDEKTPDNASEKEELQIKEKEGDLILKNIKDNMFVIALDLNGNELTSIDFSNFINDLGIKGESNLTFVIGGSLGLSSKVLSRSNYKLCFSKMTFPHQLFRVMLLEQIYRGYRIMNGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y350_CAMJ8
Sequence: MASEHSFDISAALDKQELKNAFEQAKKELDSRYDLKGIKCEIDLSEKESIFKLSSSSEGKLDVLKDIVISKLIKRGINPNAIKELSRESGAMFRLNLKANDAIDSENAKKINKAIKDSKLKVNSSIRGEEIRVAAKQIDDLQAVMKLVKELDLELNISFKNLK
What are the official names of this protein?
UPF0234 protein C8J_0350.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: SYGA_SYNP6
Sequence: MNFQSVIATLNQFWADRGCLIAQPYDTEKGAGTMNPHTFLRAIGPEPWAVAYVEPCRRPTDGRYGENPNRYQHYYQYQVLIKPSPEGIQETYLDSLRALGIQPEEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVAQFTYFQQCGGIDCRPVSIEITYGLERLAMYLQNVEAFTEIKWTDRLSYGDVHLQSEIEQCTYNFEASTPELLFQLFGLYEQEATQLIEKGLVHPSLDYVLKCSHSFNLLDARGLISVTERTRYIGRIRNMARQVAKLYLEQREQLGFPLLQKVTA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_LISIN
Sequence: MNIQIVTVGKLKEKYLVQGIAEYLKRLSAYAKVSIVEVPDEKAPEVLSDAEMKQVKDKEGVRILAKIPDDAHVIALAIDGKMKSSEEFAADLDKLATYGKSKVAFVIGGSLGLSEAVLKRSNEQISFGRLTLPHQLMRLVLVEQVYRAFRIVRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RB6I2_RAT
Sequence: MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGNSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGAETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREIARYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFRSSRSNQTNHKPSPDQDEEEGIWA
What is the function of this protein?
Regulatory subunit of the IKK complex.  Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity).  May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release.  May be involved in vesicle trafficking at the CAZ.  May be involved in Rab-6 regulated endosomes to Golgi transport.
What are the official names of this protein?
ELKS/Rab6-interacting/CAST family member 1, ERC-1, CAZ-associated structural protein 2, CAST2, Rab6-interacting protein 2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Presynaptic active zone. Note=Recruited on Golgi membranes by RAB6A in a GTP-dependent manner.
Protein: MBED_ECOLX
Sequence: MTELETHLLNALEQLQQDYMQRLSEWESAFVELQKMFSLTQRDNAMLNERVMQLSQQVQHLSEQTERLSQLYSENWR
What is the function of this protein?
This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids.
What are the official names of this protein?
Mobilization protein MbeD.
What is the protein family that this protein belongs to?
To E.coli MbaD and MbkD.
Protein: HPCA_HUMAN
Sequence: MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF
What is the function of this protein?
Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels (PubMed:28398555).  May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases (By similarity).
What are the official names of this protein?
Neuron-specific calcium-binding protein hippocalcin, Calcium-binding protein BDR-2.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=Association with membranes is calcium-dependent (By similarity). Enriched in the perinuclear region, probably at the trans Golgi network in response to calcium (PubMed:28398555).
Protein: EIF3K_MAGO7
Sequence: MPRLPNSEDPPERPDFITNIINGLERYNPEAVGTLEQYLTTQCEERFCDCNANRTLLKLYQLNPDRIKDEVITNILVKAMTLFPSPQFSQALHLLSPSALSQQSELSEAVSKLRALNNQLEGAQYARFWATIESDDLYADLTTDIQGFEEMVRLRIAVLVSQAFREVQLSLMEQWLGLDEAPLKTFITEACGFKIEGDIVQIPKNPDNEAKKAEIREDVNVEMFSRVIRRAWEEVA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGMA_MACFA
Sequence: MGGPGPRRAGTSRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLHTLPPAGDSQERSDSPEICHCEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIRAKYIGTTIVVRQVGRYLTFAVRVPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNTEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDLPGRAAAGLPLAPQPLLGALILLLALFPVFC
What is the function of this protein?
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system.  Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses.  Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition.  Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway.  It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8 (By similarity).
What are the official names of this protein?
Repulsive guidance molecule A, RGM domain family member A.
What is the protein family that this protein belongs to?
Belongs to the repulsive guidance molecule (RGM) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CRCB_HELAH
Sequence: MNLVFLWAALGGALGSSLRYFVGKMMPSKFLMFESFPLGTFSVNLIGCFVIGLMGHLAAKKVFGDDFGIFFVTGVLGGFTTFSSYGLDTLKLLQKSQYIEAISYVLGTNILGLIGVAIGWFLAKNFV
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AAS_CITK8
Sequence: MLFGFFRNLFRVLYRVRVTGDARALQGERILITPNHVSFIDGILLALFLPVRPVFAVYSSISQQWYMRWLKSLIDFVPLDPTKPMAIKHLVRLVEQGRPVVIFPEGRISVSGSLMKIYDGAGFVAAKSGATVVPVRIEGAELTHFSRLKGLVKQRFFPRIHLHILPPTHLPMPEAPRARERRKLAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCVEDINFTPDTYRKLLTKTLFVGRILEKYSAQGENIGLMLPNAAISAAVIFGAVSRGRIPAMMNYTAGVKGLTSAITAAEIKTVFTSRQFLEKGKLWHLPEQLTQVRWIYLEDLKADVTLADKLWIFAHLLMPRLAQVKQRPEEAAMILFTSGSEGHPKGVVHSHKSLLANVEQIKTIADFTANDRFMSALPLFHSFGLTVGLLTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQDSTRQLWQDKFGLRVLEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIDDGGRLQLKGPNIMNGYLRVEKPGVLEAPAAENALGDVEQGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKMHATAIKSDASKGEALVLFTTDGELTRESLLQYARTHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDEPEKQHA
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.