PharMolix/UniProtQA huggingface dataset:
Protein: GNDS_RAT
Sequence: MVQRMWAEASGPIGGAEPLFPGSRRSRSVWDAVRLEVGVPDSCPVVLHSFTQLDPDLPRLESSTQEIGEELINGVIYSISLRKVQLYPGATKGQRWLGCENESALNLYETCKVRTVKAGTLEKLVEHLVPAFQGSDLSYVTVFLCTYRAFTTTQQVLDLLFKRYGCILPYSSEDGGPQDQLKNAISSILGTWLDQYSEDFCQPPDFPCLKQLVAYVQLNMPGSDLERRAHLLLAQLEDLEPSEVEPEALSPAPVLSLKPASQLEPAPALLLTPSRAVASTPVREPAPVPVLASSPVVAPASELEPALEPPLDPEPTLAPAPELDPTVSQSLHLEPAPVPAPALEPSWPLPETTENGLCAKPHLLLFPPDLVAEQFTLMDAELFKKVVPYHCLGSIWSQRAKKGKEHLAPTIRATVAQFNNVANCVITTCLGDQSMKASDRARVVEHWIEVARECRVLKNFSSLYAILSALQSNAIHRLKKTWEEVSRGSFRVFQKLSEIFSDENNYSLSRELLIKEGTSKFATLEMNPRRTQRRQKETGVIQGTVPYLGTFLTDLVMLDTAMKDYLYGRLINFEKRRKEFEVIAQIKLLQSACNNYSIVPEEHFGAWFRAMGRLSEAESYNLSCELEPPSESASNTLRSKKSTAIVKRWERRQAPSTELSTSSSAHSKSCDQLRCSPYLSSGDITDALSVHSAGSSTSDVEEINMSFVPESPDGQEKKFWESASQSSPETSGISSASSSTSSSSASTTPVSTTRTHKRSVSGVCSYSSSLPLYNQQVGDCCIIRVSLDVDNGNMYKSILVTSQDKAPTVIRKAMDKHNLDEDEPEDYELLQIISEDHKLKIPENANVFYAMNSAANYDFILKKRAFTKGAKVKHGASSTLPRMKQKGLRIARGIF
What is the function of this protein?
Functions as a guanine nucleotide exchange factor (GEF) activating either RalA or RalB GTPases and plays an important role in intracellular transport.  Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap.  During bacterial clearance, recognizes 'Lys-33'-linked polyubiquitinated TRAF3 and subsequently mediates assembly of the exocyst complex.
What are the official names of this protein?
Ral guanine nucleotide dissociation stimulator, RalGDS, Ral guanine nucleotide exchange factor, RalGEF.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes mainly in the peripheral region of the cytoplasmic membrane in oocytes and in preimplantation embryos until the 8-cell stage. Between the late 1-cell and the early 2-cell stages, nuclear localization becomes stronger. After the 4-cell stage, not detected in the nucleus.
Protein: ARLY_DEHM1
Sequence: MSHIRSRFSKPADELVVRYTTSLPFDWRLYQEDIKCSTAHARMLGKQSIISAGDSQSIINGLSDILTEIETGSFVFKPEMEDIHMAIEGRLFELIGEAAGRLHTARSRNDQVATDVHLFVKNTCTSTINKIRTLQGALLKQAEAHQQTALPGYTHLQVAQPVLLSHHLLAYFEMLERDCGRFTDAKKRSDVMPLGSGALAGVPYPLDRKMVAEELGFTAISQNSLDAVSERDFVLEYLSDAAICQMHLSRLSEEMVIWSSAEYAFVELDDAYTTGSSIMPQKKNPDVAELCRGKTGRVYGSLNTMLTVMKGLPLSYNRDLQEDKEPLFECADTLGDSLEVFAGMIKTATFKPERMLRALEKGYVLATDIADYLVGKGESFRSSHGIVARLVSYAISQNKTFGELSLEEYRQFSNLFGNDIYAVDIKSALNARNLTGGTAPKQIAQAIARAKKILAEAGVKN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_ESCF3
Sequence: MANKPSVDDLKENLSEMQFYVTQKHGTEPPYTGRLLHNKRDGVYRCLVCDTPLFNSQSKYDSGCGWPSFYEPVNENSIRYLTDLSHGMERIEIRCGHCDAHLGHVFPDGPQPTGERYCVNSASLSFTDEKSGDQIKG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: SIA8A_BOVIN
Sequence: MSPCGRARRHTSRGAMAVLAWKFPRTRLPVGASALCVVVLCWLYVFPVYRLPDEKEIVQGVLQQGTAWRRNRTAAGIFRKQMEDCCDPAHLFAMTKMNAPMGKSLWYDGEFLYSFTIDNSTYSLFPQATPFQLPLKKCAVVGNGGILKKSGCGRQIDEADFVMRCNLPPLSSEYTKDVGSKSHLVTANPSIIRQRFQNLLWSRKTFVDHMKVYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCEDNSLQPTS
What is the function of this protein?
Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid (By similarity).  Can catalyze the addition of a second alpha-2,8- sialic acid to GD3 to form GT3 (By similarity).  Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively (By similarity).
What are the official names of this protein?
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase, Alpha-2,8-sialyltransferase 8A, Ganglioside GD3 synthase, Ganglioside GT3 synthase, Sialyltransferase 8A, SIAT8-A, Sialyltransferase St8Sia I, ST8SiaI.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: FMT_LEGPL
Sequence: MNGLTVVFAGTPEFGLPCLDALIQSRHHLKAVYTQPDRPAGRGRKLQESPVKEWAINHQISVYQPLNFKNQEAVDELSALKPDVMVVIAYGLILPKAVLEIPRLGCINVHASLLPRWRGASPIQHAILHGDAESGVTIMQMDVGLDTGPMLCKAACPVTSSDTAGSLHDKLAKMSVKPLLDVLEALASNSAQFELQNNELATYAGKINKEEARINWHQSAVEIDRKIRAFNPWPVAYTLAGELMLRIHQAKATDIMSTEMPGMVLNIDKTGMLVATSDNALLVEKIQFPGAKVISVRDWLNSGKTQLHTGLMLQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ACCD_HALHL
Sequence: MSWFQKLMPRRIRTDAGPRSRSVPEGLWTKCESCQGILYRPDLERNLEVCPKCGAHMRISARQRLRLFLDESCEAVEIGAELQPSDFLRFRDSKRYRDRLNQAQKATGENDALVAMRGAVHQRPVVVCAFEFGFMGGSMGTIVGERFCRAAEEARANDIPLVCFSASGGARMQEALFSLMQMAKTSAAISRLNEARVPYISVLTDPTMGGVSASLATLGDVIIAEPGALIGFAGPRVIEQTVRETLPEGFQRAEFLLDHGAIDMIVDRRDMRDEIASLMGKLGGDVSVAPAPAPAATVDPEPESAEPEAPAEEAGPAGAAGDQAGESQDEGDPRNA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_CHLPM
Sequence: MLKIFEKIFGSKHEKDIQKIQPVINRINEIQEGLKGLGDDELKEKGKALKSRIRGVLMPIEDKKKELYRQLDNPELSLEEAESIHSSLDALAEEYEEKTASALEEALPETFALVKETCRRLKGLTYQVMGRDVVWDMVPYDVQLIGGIVLHSGKISEMATGEGKTLVSTLPTFLNALTGRGVHLVTVNDYLAQRDKEWMNPVFDFHNISVGVILNTMRPEERRQQYQCDVTYGTNNEFGFDYLRDNMAGTVEEMVQRDFYFAIVDEVDSVLIDEARTPLIISGPVPNSDNSQFQEIKPWIEQIVRAQQQLAASYLTEAEKALKESPQSPEAGLALLRVKRGQPKNTRFIKILSQQGMAKLIQVTENEYLRDNSSRMHEVDDELYFAVDEKAGTIDLTDKGREFLSKLSHQDRDLFLLPDVGTEVAAIDDDESVIAADKITRKDAVYRLFAERSERLHNISQLLKAYSLFLKDDEYVVQNGQVMIVDEFTGRILPGRRYSDGLHQAIEAKENVKIEGETQTMATVTIQNFFRLYEKLAGMTGTAETEASEFFEIYKLDVVAIPTNRPIVRKDMDDLVYKTRREKYNAIALKVEELQKKGQPVLVGTTSVEVSETLSRMLRARRIAHNVLNAKQNEREAEIVEGAGRPGAVTIATNMAGRGTDIKLGEGVREKGGLYILGSERHESRRIDRQLRGRAGRQGDPGESVFFVSLEDELMRLFGSDRVISVMDRLGHEEGDVIEHSMITKSIERAQKKVEEQNFAIRKRLLEYDDVLNQQREVIYTRRRDGLIKERLTTDILDLLRDYCDSVIDRHSKNLDTEGIEEQLLRELSIEFKPDRNNLEENATGVSEELYNSALAFYRRKEEAVPADIMRQIEKYAVLSVIDKQWRDHLREIDTLREGINLRAYGQKDPLLEYKQEAYNLFIQMLSEIELETLSLAFKLFPVNPDEVRAIEERQRQAAVRQEKLVTQHDDAASVYNASPGAENEAPLQRPVTADSKPGRNDPCPCGSGKKYKNCHGQQP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PMS1_DICDI
Sequence: MIKAIDKESINNICSGQVIFDLSIAVKELIENSIDAGATTVEIRLKEYGEEFIEVIDNGSGVEPSNFVALTMKHCTSKLESFSDLLSIETYGFRGEALSSLCSLSNCIITTRTKNQVTAQRLVFDKEGKIQTQTPVAREVGTTVQLSNLFKGLPVRYQEFKRNIKKEYAKLLTILQAYALISTNTRITCYNQAGKSPRSCVLSTTSGSTIRDNLINVFGTKMSQSLDEFTASDSLFKVNGLISKIGIGSGTGQSISNSSSSSSQSSSQLSSSSSSSSSSQSSQLSIGSLSRSCADRQFFFVNSRPFEHSKLAKEINSLYQSFHKRGSYPVVIFNIEMPTNNYDVNVTPDKRTIFIQKEQQLLLLITDGLKTMWETAQSVFDTNQLGQFTFNDENENDNSNNNKQSKISSFPNLYTLKTEEDENNNKITTPIKKHSTTTTTSSLNSPSSNKKSSNSTSSSSSSNNKNNRNNLEEDGDDSFDITDQQPLKRAKYDGNYNNSNKKPELPKTPYPNKKKNNENEDEDEDEDNYVQPVFSNVNKSKNSSNSGSSNSLDDIIDDNEFISRSNGNSSNFMDDFEFKGSSNNIGSSSNGIKLKTISNNNNSNNSNNSNKIIDDINKTIDKMKQQQQPQQKMGLNDDGDDEEQQKQKQQQQQQKRKQQQQQQQIEEEEEETIDGYKQKNSKTFDITIKTDLNTISKQYLIRNGTFDKDNNPIIPNTALVVSNDDMVVNNNNSNEFDQNSIITTTSEKCCIVDKSIPQLDGKFSTSLGGIGAKQQQKAATQVTSQLQQQPSQTNQKTAEEELTKFFKKEYFKQMIVIGQFNLGFIIAKLGNDLFIIDQHAADEKYNFEILSKSVESSINSQPLLKPDTLSDLTSEEELIIIENVDLFKKNGFKFIIDHDAPTRFKIKLSAFPIIHGQSFGIKDIYEWIFMIKESSIPGSVNKIPRLNSLLASKACRKSIMVGTTLTHKEMKDVLNNLSTLDNPWCCPHGRPTMRHLVDLSIKDKLKQQQQQQQQKQQQQQQQ
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with mlh1 to form MutL alpha.  DNA repair is initiated by MutS alpha (msh2-msh6) or MutS beta (msh2-msh3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex.  Assembly of the MutL-MutS-heteroduplex ternary complex in presence of rfc and pcna is sufficient to activate endonuclease activity of pms1.  It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease exo1 to degrade the strand containing the mismatch (By similarity).
What are the official names of this protein?
Mismatch repair endonuclease pms1.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YL274_MIMIV
Sequence: MKNLTIGAIFLIFFAVSAFASAPCPKKLADTTCPREPYSFEGMKRQEPIKGRNVGWFQCQATMTVHDPVTTAVLVTQPTFTFNLSTLYHNSCGCWKTVTTIPGDAVKMEYGNGLPGQAMYGSCFYATWADLAGNPVETVGFARNVVGVHRDLIYVSRATNELVVHQSIYPLGRDQVGDEYVLVRHFDPVTKGIDWVQAVYCTKIQDQLEPLP
What are the official names of this protein?
Uncharacterized protein L274.
What are the subcellular locations of this protein?
Virion.
Protein: IF4A2_BOVIN
Sequence: MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-II, eIF-4A-II, eIF4A-II, ATP-dependent RNA helicase eIF4A-2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: TS1R2_CANLF
Sequence: MGPRAKAVCSLFILLQVLAEPAENSDFYLPGDYLLGGLFTLHANVKGTVHLSFLQVPQCKKYEMKVLGYNLMQAMRFAVEEINNRSDLLPGVLLGYEIVDVCYISNNVQPVLYFLAREDYSLPIQEDYSHYVPRVLAVIGPDNSESTTTVAHFLSLFLLPQITYSAISDDLRDKQHFPALLRTVAGADHQIEAMVQLLLHFNWNWIIVLVSSDDYGRYNSQLLNDRLATGDICIAFQETLPMPQPDQVVTEWERQRLEAIVGKLQQSSARVVVLFSPDLILHNFFREVLRQNFTGAVWIASESWAIDPVLHNLTELRQTGTFLGVTTQSVPIPGFSEFRIRRTPVRLPEPNRTSLEATCNQECDTCQDTTASFNSILMLSGERVVYNVYSAVYAVAHALHSLLGCTQACSKEVVYPWQLLKEIWKVNFTLLGHNVFFGQQGDVLMPMEVIQWQWDLSQNPFQSIASYYPKLRQLKAIHNISWHTANNTIPVSMCSKDCHPGQRKKPVGIHSCCFECIDCLPGTFLNRTADEFDCQPCPSYEWSHRNDTSCFKRRLAFLEWHEPSTIFVVMLTILGFLSTLAIMVIFWRHLHTPVVRSAGGPMCFLMLVPLLLAYAMVPMYIGQPTFFSCLWRQTFFTLCFTICISCITVRSFQIVCIFKMARRLPRAYGYWVRCHGPYVFVASFMVLKVVIVAGNVLATTANPTARPDPDDPNIMVLSCNYRRALLFNTSLDLLLSVAGFSFAYMGKELPTNYNEAKFITLCMTFYFTSSVSLCTFMSVYDGVLVTILDLLITVLNLLGISFGYFGPKCYMVLFYPERNTQVYFSSMIQGYTMGKD
What is the function of this protein?
Putative taste receptor.  TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners (By similarity).
What are the official names of this protein?
Taste receptor type 1 member 2, Sweet taste receptor T1R2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: I2BB_CONIM
Sequence: MFRLTSVGCILLVIAFLNLVGLTNACTSEGYSCSSDSNCCKNVCCWNVCESHCRHPGKRTRLQGFFKHRR
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Im11.11, Conopeptide im008.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DDL_ALKEH
Sequence: MSSEQAAAMGRVAVLMGGDSAEREISLISGRAVFEALRRRGVDAEAVDTAQVALAELTGFDRAFIALHGRGGEDGVIQGALEALGVPYTGSGVLGCAIGMDKWRTKLLWRGAELPVPPGALLRPETNRQALIGSVGLPLMIKPAHEGSSIGMAKVERPEELEAARAEAARYDDLVLAERWIEGGEYTVAILGEEALPAIRLETPRGFYDFEAKYRSGDTRYHCPAGLTEAEEQQIRQLALDAFRVAGASGWGRVDFMRDRQGRFWLLEINTIPGMTDHSLVPMAARAVGIDFDELCWRILLDSRRREAGRP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RH34_ARATH
Sequence: MEGTLDEENLVFETTKGIKPIKSFDDMGMNDKVLRGVYDYGYKKPSEIQQRALVPILKGRDVIAQAQSGTGKTSMIAISVCQIVNISSRKVQVLVLSPSRELASQTEKTIQAIGAHTNIQAHACIGGKSIGEDIKKLERGVHAVSGTPGRVYDMIKRGSLQTKAVKLLVLDESDEMLSKGLKDQIYDVYRALPHDIQVCLISATLPQEILEMTEKFMTDPVRILVKPDELTLEGIKQYYVDVDKEEWKFDTLCDLYGRLTINQAIIFCNTRQKVDWLTEKMRSSNFIVSSMHGDKRQKERDDIMNQFRSFKSRVLIASDVWARGIDVQTVSHVINYDIPNNPELYIHRIGRAGRFGREGVAINFVKSSDMKDLKDIERHYGTKIREMPADLV
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 34, AtRH34.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL40_METAR
Sequence: MARFPEAEARTLNLQICRKCNARNALRATRCRKCGYEGLRPKKKELKK
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: DUT_HAEIG
Sequence: MKKIDVKILDSRIGNEFPLPTYATEGSAGLDLRALIDESFEIQPGETKLIPTGLSIYIADPNLAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVSMWNRGNEPFKIEVGDRIAQLVFVPVVQAEFNIVEDFQQTERGEGGFGHSGKQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: IF2_HELAH
Sequence: MSGMVDLKEFLAELGKTQKELKNVIEQAKDIGLELRTNSKMTPEEAEKLYKYIVDGIKEQIQSNRPIKKDKEGAATPKASNKKTSKTPKKEEAKSQLKPKNTKKKKKEAPTPILKKKGIEIVDTFENKTPPVENAPKVVTPSQSQIEKAKQKLQEIQKSREALNKLTQSNTNNANNANSAKKEISEVAKQEREQEHLDNKRRENIKRYTGFRVIKRNDDENETQNSVTENKKPTQSAVAIFEDIKKEWQEKDKETKKAKKSNKPKAIPAAKNNKSHKIDFSDARDFKGNNDIYDDETDEILLFDLHEQDNLNEEEEKEIRQNINDRARIQRKNPWMNEGGIKRQSKKKRVFRNDNSQKVVQSVISIPEEVCVYEFAQKANLNLADVIKTLFNLGLMVTKNDFLDKDSIEILAEEFHLEISVQNTLEEFEVEEVLEGVKKERPPVVTIMGHVDHGKTSLLDKIRDKRVAHTEAGGITQHIGAYMVEKNGKWVSFIDTPGHEAFSQMRNRGAQVTDIAVIVIAADDGVKQQTVEALEHAKVANVPVIFAMNKMDKPNVNLDKLKAECAELGYNPVDWGGEYEFIPISAKTGDGIDNLLETILIQADIMELKAIEEGRARAVVLEGSVEKGRGAVATVIVQSGTLSVGDSFFAETAFGKVRTMTDDQGKSIQNLKPSMVALITGLSEVPPAGSVLIGVENDSIARLQAQKRATYLRQKALSKSTKVSFDELSEMVANKELKNIPVVIKADTQGSLEAIKNSLLELNNEEVAIQVIHSGVGGITENDLSLVASSEHAVILGFNIRPTGNVKNKAKEYNVSIKTYTVIYALIEEMRSLLLGLMSPIIEEEHTGQAEVRETFNIPKVGTIAGCVVSDGVITRGIKVRLIRDGVVIHTGEILSLKRFKDDAKEVSKGYECGIMLENYNEIKVGDVFETYKEIHKKRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTC5_CANTT
Sequence: MGQATSNIDPQEKRDIVQEFTKEELQTLFYHRCLSLLKPIEVAFLKQDLNGKTSVTADDLGKLFKFPENTNSFSEGTLNILYHVMKLIGKFPFINNNNLAIEETLSFEELVVSLVFFSGRYKKIFNSDYDFLKLLFISLSDRPQTKDSKTIDEKNVDPGTEKFKTNLIVALEEEDKQELRARKINWSKLDVIKDFDHTEVQQLSVNAKRLQDMTTLCLILNAIVRHNHDAIQKQLVEYSDRWREFEVYSLYLLRYLDVYLELDKLENQKISYDSFSKGINGLLPYFFQINLNRMVCDSLLSSNSPMATKPTEEHNDSTESTPQKKHTFPKFQETKVVSIPFLSYVSSMLQGIGNPTILSPSNLVKLYAGSEAGFSIRSLETKIFKWQAPTLVVVSGKRLKSKTMQTNRRYQKFDEMYPRHFLASENHLRDWQHESDRITYAVLVNQPWKSSNKNNFGDEKSIILSISPRADYFKSVHSSILQGQSIYFNNLGMGLGFGNNQPLNKNDTKRFIPGDMSLTIEANLEFAVFRHLVNSSSSNDKFFHNSQQSHISHEDYEDRFTISTIEVWGLLVSGKELEEQKKQWEWEEKQAEARQNVNIRNLGEERAFLEMAGLVGNHGAAGGSM
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAR_ECO27
Sequence: MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPEILQQLEAQGVSIMRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IGHG2_HUMAN
Sequence: ASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDISVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPELQLEESCAEAQDGELDGLWTTITIFITLFLLSVCYSATITFFKVKWIFSSVVDLKQTIVPDYRNMIRQGA
What is the function of this protein?
Constant region of immunoglobulin heavy chains.  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin heavy constant gamma 2, Ig gamma-2 chain C region, Ig gamma-2 chain C region DOT, Ig gamma-2 chain C region TIL, Ig gamma-2 chain C region ZIE.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: MDFA_EDWTE
Sequence: MQNRLSSTRRLGRRALLFPLCLVLYEFATYIGNDMIQPGMLSVVQTFGVDESWVPTSMTAYLAGGMFLQWLLGPISDRIGRRPVMLTGTLYFAVTCLAILLTNSIEQFTLMRFLQGISLCFIGAVGYAAIQESFEESVCIKITALMANVALIAPLLGPLAGAAWVHLFPWEGMFILFAALSLLAFLGLYKAMPETATRRGETLSLSALGHDYALVLKNKRFLGGALACGFASLPLLAWIAQSPVIIISGEGLSSYDYGMLQVPIFGMLILGNFTLARLSGRRPVRRLIQLGAWPMVGGLAIAAVSTLYSAHAYLWMTAGLSLYAFGIGLANAGLYRLTLFSSTMSKGTVSAAMGMISMFIYTLGIEVGKHAWLLGGNGAFNLFNLISGLLWLALVALMLRDKRVGGTTER
What is the function of this protein?
Efflux pump driven by the proton motive force.  Confers resistance to a broad spectrum of chemically unrelated drugs (By similarity).
What are the official names of this protein?
Multidrug transporter MdfA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. MdfA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TUS_SALAR
Sequence: MSCYDLVERLNGTFRQIEQHLAALTDNLQQHSLLIARVFSLPQVTKEAEHAPLDTIEVTQHLGKEAETLALRHYRHLFIQQQSENRSSKAAVRLPGVLCYQVDNATQADLENQVQRINQLKTTFGQMVTVESGLPSAARFEWVHRYLPGLITLNAYRTLTLINNPATIRFGWANKHIIKNLSRDEVLSQLKKSLSSTRSVPPWTREQWQFKLEREYQDIAALPQQARLKIKRPVKVQPIARIWYKGQQKQVQHACPTPIIALINTDNGAGVPDIGGLENYDADNIQHRFKPQAQPMRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U540B_ARATH
Sequence: MNATKFVVLLVIGILCAIVTARQVEEVSKETKLGTSLPKSTNKGIGAQLSAAGLTYSGSSVSSSASAFNNPKGPGASASESGYTSTIGQVIAKGRKARVSSASASAATGEAAAAVTRKAAAARAKGKVASASRVKGSSEKKKKDHKGKKD
What are the official names of this protein?
UPF0540 protein At1g62060.
What is the protein family that this protein belongs to?
Belongs to the UPF0540 family.
Protein: PYRD_AZOVD
Sequence: MYTLARQLLFKLSPETAHELTIDLLGAGGRLGLNGLLCHRPASLPVRVMGLDFPNPVGLAAGLDKNGDAIDGLAQLGFGFVEIGTVTPRPQPGNPRPRLFRLPQAEAIVNRMGFNNLGVDHLLARVQAARYSGVLGINIGKNFDTPVERAVDDYLICLDKVYPHASYVTVNVSSPNTPGLRSLQFGDSLRQLLEALRQRQEELAGRHGRRVPLAIKIAPDMSDEETAQVARALLDTGMDAVIATNTTLGREGVEGLAHAGEAGGLSGAPVREKSTHAVRVLAGELGGRLPIVAVGGITEGRHAAEKIAAGASLVQIYTGFVYKGPALIREAVEAIAALRGERPVGTH
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KGUA_AYWBP
Sequence: MKLNKKGLLIILSGPSGVGKATVRKALFEMTNHNFVYSVSATTRKPRPGEQDGKDYHFLTKEEFEKGIENNCFLEWAKFIDHYYGTPKKQIQDFLKQGKEVFLEIEVEGATHLRKKRMPNTVFIFLVPPKKKDLYDRLKKRGTEQEINIVQRIAKANNEFRLAHKYDYIVVNDEVANAADRIIAIIRAEHAKTKRSIRNYLKILEDNVYAE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.