PharMolix/UniProtQA huggingface dataset:
Protein: PSBA_KARMI
Sequence: MKSTLLNKKSQQTTPAWEFFCSWVTTTENRLYLGWFGCLMVPTLVSATFAYIIGFLAAPPVDIDGIREPVSGSLLYANNIISGAVIPSSNAMGVHFYPIWEAASLDEWLYNGGTYQLVVFHFFIGVCSYLGREWELSYRLGMRPWIFVAFSAPVAAASAVFIVYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPLHMFGVAAVFGGSLFSAMHGSLVTSSLLKETAEFESANYGYRFGQSTETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGAWPVVGIWLTAMGVSTMAFNLNGLNFQQSILDASGCPINTWADILNRANLGMEVMHERNAHNFPLDLACANCLLSLWPMVG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRMN6_KLEP3
Sequence: MSQSKFALPRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPIAGVKHVLDIGAGSGLLALMLAQRTDHDVQVDAVELDEEAAAQARENALASPWSSRIEVCQADIHQWQPSQTRRYELIISNPPFFAEGVPCATSQREQARYTTTLDHASLLTCAAEHITEEGFFCVVLPVDIGNAFIERATAMGWHLRLRTDVAETELRPPHRVLLAFSPTAGECFCDRLAIRGPEQQYSEGFTALTGDFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O52A1_HUMAN
Sequence: MSISNITVYMPSVLTLVGIPGLESVQCWIGIPFCAIYLIAMIGNSLLLSIIKSERSLHEPLYIFLGMLGATDIALASSIMPKMLGIFWFNVPEIYFDSCLLQMWFIHTLQGIESGILVAMALDRYVAICYPLRHANIFTHQLVIQIGTMVVLRAAILVAPCLVLIKCRFQFYHTTVISHSYCEHMAIVKLAAANVQVNKIYGLFVAFTVAGFDLTFITLSYIQIFITVFRLPQKEARFKAFNTCIAHICVFLQFYLLAFFSFFTHRFGSHISPYIHILFSSIYLLVPPFLNPLVYGAKTTQIRIHVVKMFCS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 52A1, HPFH1OR, Odorant receptor HOR3'beta4, Olfactory receptor OR11-319.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_STRGT
Sequence: MLIAQRPSLTEEVVDEFRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTDLILNIKQLVVSSEHDEPVVMYLRKQGPGLVTAADIAPPAGVEVHNPDLVLATLNAKGKLEMELTVERGRGYVSAVQNKQVGQEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLIVDVETKQAMRPRDAMASAGKTLVELFGLARELNIDAEGIDMGPSPTDAALAADLALPIEELELTVRSYNCLKREGIHSVGELVARSEADLLDIRNFGAKSIDEVKAKLAGMGLALKDSPPGFDPTAAADAFGADDDADAGFVETEQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: VP35L_DROME
Sequence: MANLEWVCVPRCYEVRKNCLTGQATLEHPLKQRTVTVVDSNPLSRALEGTDPLSQFARQDDELNDPLSQMVSEFDLKSKRRERDRTEPEDNTLQWSSRRLGILNRFTTNEKLSLSTSFLVSSGSLDGGNESIKAQTVVADKTKFRLEQLDHFDDGSMRHMMDLTQQEYIQRFEQLKQELIQSWHNDQRVKALKIAIQCAKMLADTTVLQFYPSQYVLITDILDVFGKLVYERLRAKASGDPAASAATLEREREAARDTCQNWFYKIASIRELLPRFYLELSIFKCYEFLSSSREEYERILQRLTHQLRGIADPLVSSYARCYLVRMGVTLTSSKTYIRENFADLFLIYPQIFRFVARFNLHPEIVTASSYLQLYAPAFDYMLLCLVHKSELHTQDILNECKQLKNNGAILMSVLSSFNSEFIATNALEFIALINASETPGISKSQLLRSLGSCVSSCPPLQEQRVTFLKAAFETINKLTDPNEYINCVETWAVFVSQYFTIHEVNRLLGELNTRMCLGKAYEKHYSQLQNILTRIMQNYRSIELLLIQPNFLPYLDLFQKESVRVEVCKNILSFYKQNSDEYTCDAVVTNALMYLGKILNDSVNALSVDDERRQIAQLINVFIHKVHFGNDLEQQLSFYVEARGTFSNLDAVYVTLVHAACKLATRNRSKSTGFVKACIAYCFITIPSIEAVQQQMNLYLLCGQLALQHLCLGQADACFEAALQLVNELPAATVDFDGKPRSLEPFLVSYMCNILATLIVVPDSPEQGVLYFLRLLLEVVGRHKFKVDSSAPSIIYLHSLDMLYVQSLERFPYHIKGVVSNDDLYGHDPKFLQEVNNMCAQVVDAILLQLKSLGVAQQQRSQAELALELFLRIVKYADLERETIAQLAVNLWLLANKAQSQLDVKTLPQTLRSVEIIYKQIKDASPIRAQTIAKLLLRVRSS
What is the function of this protein?
Acts as component of the retriever complex.  The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos.
What are the official names of this protein?
VPS35 endosomal protein sorting factor-like.
What is the protein family that this protein belongs to?
Belongs to the VPS35L family.
What are the subcellular locations of this protein?
Endosome.
Protein: RS10_BARHE
Sequence: MNSQNIRIRLKAFDHRILDASTREIVSTAKRTGANVRGPIPLPTRIEKFTVNRGPHIDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: OTC_CORGL
Sequence: MTSQPQVRHFLADDDLTPAEQAEVLTLAAKLKAAPFSERPLEGPKSVAVLFDKTSTRTRFSFDAGIAHLGGHAIVVDSGSSQMGKGESLQDTAAVLSRYVEAIVWRTYAHSNFHAMAETSTVPLVNSLSDDLHPCQILADLQTIVENLSPEEGPAGLKGKKAVYLGDGDNNMANSYMIGFATAGMDISIIAPEGFQPRAEFVERAEKRGQETGAKVVVTDSLDEVAGADVVITDTWVSMGMENDGIDRTTPFVPYQVNDEVMAKANDGAIFLHCLPAYRGKEVAASVIDGPASKVFDEAENRLHAQKALLVWLLANQPR
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTB12_MYCBO
Sequence: MKMVKSIAAGLTAAAAIGAAAAGVTSIMAGGPVVYQMQPVVFGAPLPLDPASAPDVPTAAQLTSLLNSLADPNVSFANKGSLVEGGIGGTEARIADHKLKKAAEHGDLPLSFSVTNIQPAAAGSATADVSVSGPKLSSPVTQNVTFVNQGGWMLSRASAMELLQAAGN
What is the function of this protein?
May play a role in the development of protective immune responses.
What are the official names of this protein?
Low molecular weight antigen MTB12, CFP-2, Low molecular weight protein antigen 2.
What is the protein family that this protein belongs to?
Belongs to the MTB12 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF3_RIPO1
Sequence: MSSELQTEIQEAVEKRRNFAIISHPDAGKTTLTEKLLLYGGAIHQAGAVKARRDQRKATSDWMEMEKQRGISITSTVLQFEYRNFQINLLDTPGHQDFSEDTYRTLAAADNAVMLIDAAKGLEPQTRKLFEVCRLRGLPIFTFINKLDRPTREPLELLDEIEQELGLKTYAVNWPIGTGDRFKGVFDRRHQGIHLFERRAHGSQQAQETAIKLGDPKIEAHLEQELYYQLKEELEILQELGGDLDLKELHDGQITPVFFGSAMTNFGVQLFLEAFLEYALQPEGRNSSVGVVDPTHPEFSGFVFKLQANMDPKHRDRVAFVRVCTGKFEKDMTVSHARTGKTVRLSRPQKLFAQDRESIEEAYGGDVIGLNNPGVFAIGDTIYSGTKLEYEGIPCFSPEIFAYLKNPNPSKFKQFQKGIQELREEGAIQIMYSTDDFKRDPILAAVGQLQFEVVQFRMLSEYGVETNLEPLPYSVARWVTGGWTALEKAGRIFNSMTVKDNWDRPVLLFKNEWNLNQVKADKPELGLSSTAPVGSGINE
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_BUCA5
Sequence: MNFEVLYQDNNARCGVFNFNQEIIETPVFMPVGTYGAVKSISTEEIKNTGSRIILSNAFHLYFRPGLEIIKLHGNLHNFMNWSGPILTDSGGFQVFSLSRFCKVNEEGVIFQNHIDGKKTFLTPKISMKIQSDLGSNIVMIFDQCIEYNQNWEKTKNAMERSLYWAKKSRIYFDSYKNKNSLFGIIHGGIYPSLRDISLQELIKIDFDGYALGGLAVGEPKIEMYKLLDHICPQIPKNKPRYLMGVGKPEDLIEGVRRGVDMFDCVIPTRNARNGHLFVTNGVIKIRNKKYKKDLSCLDKTCVCYTCRYYSRSYLHHLDACNEILGARLNTIHNLHYYQTLMSNIRNSIKNNTFEQFSLNFYKQKNKIDF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: NUSG_RICCN
Sequence: MTAQSIDNILSSSEKNVKQWYVVHTASGAEKRIKEDMLRKIAKQNMTHFFEDILIPVFGVSEVKRGKNVKVEKKLMPSYILIKMNMTDKSWHLVKNISGVTGFLGSKTTPKALTESEIQNIFNNLEAEAKEAKNSKLYEVGEIVTVTDGPFETFMGTVEEIDQEKNRLKVSVAIFGKATPIELNFNQVKKND
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: RR14_PINKO
Sequence: MARKSLIQREKKRQALERKYHLIRQSLEEKSKVSSLDDKWEIHRKLQSSPRNSAPTRLHRRCSSTGRPRANYRDFGLSGHILREMAHACLLPGITKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TIG_VEREI
Sequence: MAVTVETLDKLERKMTLSLPVTLIQSEVDMRLRRMARTVKMDGFRPGKVPMAVVARRYGDAVQYEVLTNKVGEAFTVAANEANLRVAGRPRITETQGTAEGHVTFDAIFEVFPEVRIADLANVEIEKLSTEVTEASIDKTLQGLRKQRRSFAQRAHDAPAQDGDGVTVDFEGKIDGEPFANGKAENFRFVIGEGPMPKEFEDAVRGMKSGESKTFPLAFPTQYHGQEVAGKTADFLVTVKKIESAHLPEVGEALARSLGSADGSIEGLRADIRKTLEREIRSHLRARNRRAVMNALLANADLELPKASVQDEIARLKANAYADLKQRGVKDPERLEIPEDKVRPTAERNVRLRLIFSEMVRAHGLRAKPEQVRAYVEELAASYEKPAEMVRGYYGDRRRMLEIESSVSEDNVTEFVFARAKVVARTISVDELLNPKDPKD
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CISY_PYRFU
Sequence: MNTEKYLAKGLEDVYIDQTNICYIDGKEGKLYYRGYSVEELAELSTFEEVVYLLWWGKLPSLSELENFKKELAKSRGLPKEVIEIMEALPKNTHPMGALRTIISYLGNIDDSGDIPVTPEEVYRIGISVTAKIPTIVANWYRIKNGLEYVPPKEKLSHAANFLYMLHGEEPPKEWEKAMDVALILYAEHEINASTLAVMTVGSTLSDYYSAILAGIGALKGPIHGGAVEEAIKQFMEIGSPEKVEEWFFKALQQKRKIMGAGHRVYKTYDPRARIFKKYASKLGDKKLFEIAERLERLVEEYLSKKGISINVDYWSGLVFYGMKIPIELYTTIFAMGRIAGWTAHLAEYVSHNRIIRPRLQYVGEIGKKYLPIELRR
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: RLME_RHIWR
Sequence: MSRAGNGGRQRIKTAKGRSASSIKWIQRQLNDPYVRKAQAEGYRSRAAYKLIELDERFHFLRGAKRVIDLGIAPGGWTQVVRRVCPQAAIVGIDLLPTDPIDGAIILQMDFMSDEAPAQLAEALGGPADIVLSDMAANTVGHQQTDHLRTMALVEAGCLFASEVLRPGGTYVAKVLAGGADHGLVAELKRLFTTVKHAKPPASRKDSSEWYVIAQGFKGRPEAAGADGE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_DEIGD
Sequence: MANERNQQNLTSLRGSLTGVETFYVVDYQGLTAGQLSQLRKNIREKGGQLIVAKNTLINLALQESGRDFSDALKGPSALVLAQEDPAGVAKALSDAAKGNDKGIPAIKGGFVEGNRVDVRVVERLASLGSKQSLQGELVGVLSAHLSNFVGILEAYRDKLGGGAAEAQG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: Y034_METJA
Sequence: MSIKEELMEIIEAIKYTSEKPEEIVHGKGPRIIVKESRIIDVQGDEGIILEGKEEDGKIKAKIIVKKGYKFKYPIHMCFGITEENISQIIDVEIILEEDSSISLMSHCSFPKGKGIKHIMNGIIKIGKNAKFSYNEFHYHGMDGDILVKPTVKVEIDEGGIYISNFTLTKGRIGTLDIEQEIIAKKDAIIDITTRTYAIKEDVVKVNEVVKLNGENAKCIIKSRGAAMDNSKISLKLKIEGNAPYSKGHIDCAEIVKGNAEVESIPIVVVRDDKARITHEAAIGSVDKKQLETLMAKGLDEDEATEIIVKGMIGDL
What are the official names of this protein?
UPF0051 protein MJ0034.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: LEU1_ACESD
Sequence: MNYKKYKGYETIVLEDRNWPSRKIEKAPQWCSVDLRDGNQALITPMGLKQKLRFFEYLVKMGFKTIEIGFPAASDTEYEFTRTLIEEGYIPEDVTIQVLTQSRIQIINKTFEALKGTKNAVVHLYNSTSTLQREVVFRNSKEETIELAVFGARAIKELALKNPETNFTFEYSPESFTGTEMDFAAEICNSVIDVWKPTKDKKVIINLPSTVEMATPNTYADQIEYMCRNLKSRENIIVSLHAHNDRGTGVAATELGLMAGADRVEGTLFGNGERTGNADILNLGMNLYTQGINPELDFSDINSMIEIYEESTAMNVHPRHPYAGDLVFTAFSGSHQDAIKKGMARMNKQAQYWEVPYLPLDPKDIGKSYEPIIRINSQSGKGGVSFILEQNYGLYIPKDFQKDAGRVITAYSDKMQTEIGAEEIYEVFLNEYVDIRTPLQLNYHKTQSVDSDWDLVFIEAEIEYNMQKHYVQAEGNGVVSAFCNSLKEIIGMDIDIVDYRGHSMEYGTKAKAISYIELKNETGERFYGAGTSSSVGKSSLRAVVSAINKMILAQQTKDMDTQEEDIA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: CLP1_YARLI
Sequence: MSLPGLNFSTTETNTTESTHTIDLKPETEWRYEVAIGGTLHVTLKSGTAEIFGTELPPNKELSIQGKGSIYTWQGCQFVYTAIAGPKGLMSDYTTEDTPHMTMAINLHFALEKMRNEAEQKPKDVAGPRVLIAGPPNSGKTSLAKILLAYATKCDRKPIYISLDPTSVNLGPPGGVHAVQITDLLDVETYGGFGSSEISGPQKLQPLILLSKYFGLEKTTDNFKLFKRSVAQLAVPVLSKLAHDVEAQKSGLIIDTPRVPGNQNKTIEVNLLTDVVSDFGVNVIVVIGNDRLYADLMKKYPVGASGPTVVKVPAFACMDDDESYNRDAQQQEIQQYFYGDAKDMKLGPRIVTVDFSTLHVYKIKPSTQFDDDKADMLERVAEANILPNTVLTVMHAVPGSSEKEILDSEVQGYLHVTEVDEEKNKVKILTPVPGRLPSQVMLLGDTRYHE
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor CLP1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUTD_ECOUT
Sequence: MRISPSEAAMKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLVQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTVLVSVNGWLRINAHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: ILVC_CHLCH
Sequence: MNVYYEKDADLAYLQGKKIAVLGYGSQGHAHSLNLHESGLNVRVGLRPESASCAKAREAGLEVTSVAEATKWADIVMVLLPDQNQKAVYEAEIAPNLEPGNTLAFGHGFNIHYKQIVPASSVNVIMIAPKSPGHLVRRTYTEGNGVPCLIAVHQDPTGEAKQQALAWAKALGGTKAGVIETNFKNETETDLFGEQAVLCGGSAELIKAGFETLVEAGYPEELAYFECMHELKLIVDLYYEGGLSRMNYSVSDTAEYGGMTRGPRLITPAVKAEMKKILEEVQDGRFAKEFIDECNGGYQNLSKLRESNSNHAIEKVGAKLRNMMSWLIKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: METE_RHILO
Sequence: MATLGVPRIGRRRELKFALESYWSGKSPAADLLATAKALRAASWREQHDRGVSKIPSNDFSLYDHVLDTVAMVGAVPARYTWTDGEVPLDTYFAMARGNQDQAADCGHAGDEHAANGHGLAAMEMTKWFDTNYHYIVPELTDDQSFALSSAKPVDHFLEAKALGIHTRPVLLGPVTFLKLAKSPEEGFNPIALLPRLLPVYEELLRRLKLAGADWVQIDEPALVVDLVPNERDALQFAYCRLSKAAPELKIMVAIYFGSLGDNLETAISLPVAGLHVDLVRAPEQLETVGRLAQKDLVLSLGLIDGRNVWRANLPAILDRIKPIVAGWPLDRVEIAPSCSMLHVPIDLDMETALDADVKSWLAFAAQKTDELVVLARALAEGRDAVAAELEASAEAAAARATSAKVHDPLVEGRVASIKVAMTRRKSAFDVRSKLQGDTFGLPSFPTTTIGSFPQTAEVRKARAAHAKGELSYVDYEAFLKKEIEAAVRWQEEIGLDVLVHGEFERNDMVQYFAEQLRGFAFTQHGWVQSYGSRFVRPPIIIGDVSRQNPMTLHWWRYAQSLTPKPVKGMLTGPVTILNWSFVRDDLPRSAVCRQVALAIRDEVSDLEKAGAKMIQIDEAALREGLPLREADWQAYLDWAVECFRLASTAVGDATQIHTHMCYSEFGDIVDAIAAMDADVISIETSRSQLELLDTLRTFKYPNEIGPGVYDIHSPRVPEVGEISNLIMLARKRLSDGQLWVNPDCGLKTRRWEEVRPALVNMVAAARAIRQKAQTA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: TOLB_HELHP
Sequence: MRFIGLVLLLLSVKLFGIDATLEIVKNTNKIPYIVVERLDSENADFGAKVLKMLAADLKVSGHFQVYDGSVNKNSEVAYKDYADKKIDLLAQIKVSKSSNSLTGTISLYDINTSKRIYVKDYTENDVKRFPFIAHRMCIDVNSYIQAPSIEWMQRLVVLSQYTTSGNSEILIADYTLTYQKVVVKGGLNIFPKWVDSKQESIYYTKYLDVPTILKHNLTTGHIEQLVGSEGIAVVSDVSKNGENLILSLSPTALSDLYLYNTKSKNLRRLTNYSGIDVDGKFVNNEKEIIFVSDRLGYPNIFMMRLDGGGTEQVVLHGRNNSAVTSNGKYAVYTSRETNNEFGANTFNLYLISLAPGSNYIRRLTASGKNQMPKYSNDGGTIMYLKYYKAQSALGIIRIDYNTNYFFPLIKMKIQAFDW
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATPG_ACIB3
Sequence: MANLKEIRAKVASIKSTQKITRAMQMVAASKMRRAQERMAQGRPYADNMRRVIAHLVQANPEYKHRYMVDRPVKRVGYIIVSSDRGLAGGLNINLFKKVVQHVKAQQEQSIEVQFALIGQKAVSFFKNYGGKVLGATTQIGDAPSLEQLTGSVQVMLDAFDKGELDRIYLVSNGFVNAMTQKPKVEQLVPLAPAEEGDDLNRTYGWDYIYEPEAEELLNGLLVRYIESMVYQGVIENVACEQSARMVAMKAATDNAGQLIKDLQLIYNKLRQAAITQEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GATB_LODEL
Sequence: MLRRYLATSASATASATATASASASASASKNSIKSNFKFHPEYKFKCGLEIHTQLKTKYKLFSLSRTSFNDTPNSHISYFDVGLPGTQPKLNPEALYLALKAAVALNCEVQQMSRFDRKHYFYPDQPMGYQITQNFHPLAKNGYLTFNEFDGVEIATSKDGANDTIRIEKIQLEQDTGKKYGDIIDYNRAGIPLIEVVTKPDFDSIEKVLAFVKKYQLLVRHFDICSGDLETGAIRVDVNVNVNDSPRVEIKNISTTGDIVNAIKYEYNRQVETLTKGGSLEQQTRNWDGIRTNLARSKENAIDYRYFPDSELPQIILSPDIAHDIKTSLPESPDSLLARLTSSPHNLQLAHAKNLITEPELLHYYESFFAIHRKPDADKWVFQELLTAFAKLGKTFDVEIVKPNVFAHLVSMDLNLVSKRLILKHMVQNEVSLDKAIEQLGFKEDQKPTTELAEDICKEIILTNQQIVDRIQSGHAKAVEVLVGNAMKKTRGKFAAQTFRSLFKEQLGIS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DEF_STRT1
Sequence: MDAQTKIIRASHMIDMNDIIREGNPTLRAVAEDVTLPLSDEDIILGEKMMQFLRNSQDPVIAEKMGLRGGVGLAAPQLDISKRIIAVLVPNPEDAKGNPPKEAYSLQEIMYNPKVVAHSVQEAALGNGEGCLSVDRDVPGYVVRHARVTIEYFNKEGEKKRIKLRGYDSIVVQHEIDHTNGIMFYDRINKDNPFTIKDGLLIIE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.