PharMolix/UniProtQA huggingface dataset:
Protein: MMS19_ARATH
Sequence: MMVEPNQLVQHLETFVDTNRSSSQQDDSLKAIASSLENDSLSITQLVREMEMYLTTTDNLVRARGILLLAEILDCLKAKPLNDTIVHTLVGFFSEKLADWRAMCGALVGCLALLKRKDVAGVVTDIDVQAMAKSMIQNVQVQALALHERKLAFELLECLLQQHSEAILTMGDLLVYAMCEAIDGEKDPQCLMIVFHLVELLAPLFPSPSGPLASDASDLFEVIGCYFPLHFTHTKDDEANIRREDLSRGLLLAISSTPFFEPYAIPLLLEKLSSSLPVAKVDSLKCLKDCALKYGVDRMKKHYGALWSALKDTFYSSTGTHLSFAIESLTSPGFEMNEIHRDAVSLLQRLVKQDISFLGFVVDDTRINTVFDTIYRYPQYKEMPDPSKLEVLVISQILSVSAKASVQSCNIIFEAIFFRLMNTLGIVEKTSTGDVVQNGNSTVSTRLYHGGLHLCIELLAASKDLILGFEECSPTSGCANSGCSMVKSFSVPLIQVFTSAVCRSNDDSVVDVYLGVKGLLTMGMFRGGSSPVSRTEFENILVTLTSIITAKSGKTVVWELALKALVCIGSFIDRYHESDKAMSYMSIVVDNLVSLACSSHCGLPYQMILEATSEVCSTGPKYVEKMVQGLEEAFCSSLSDFYVNGNFESIDNCSQLLKCLTNKLLPRVAEIDGLEQLLVHFAISMWKQIEFCGVFSCDFNGREFVEAAMTTMRQVVGIALVDSQNSIIQKAYSVVSSCTLPAMESIPLTFVALEGLQRDLSSRDELILSLFASVIIAASPSASIPDAKSLIHLLLVTLLKGYIPAAQALGSMVNKLGSGSGGTNTSRDCSLEEACAIIFHADFASGKKISSNGSAKIIVGSETTMSKICLGYCGSLDLQTRAITGLAWIGKGLLMRGNERVNEIALVLVECLKSNNCSGHALHPSAMKHAADAFSIIMSDSEVCLNRKFHAVIRPLYKQRCFSTIVPILESLIMNSQTSLSRTMLHVALAHVISNVPVTVILDNTKKLQPLILEGLSVLSLDSVEKETLFSLLLVLSGTLTDTKGQQSASDNAHIIIECLIKLTSYPHLMVVRETSIQCLVALLELPHRRIYPFRREVLQAIEKSLDDPKRKVREEAIRCRQAWASITSGSNIF
What is the function of this protein?
May select specific target apoproteins to which a Fe-S cluster produced by the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) pathway is transferred.
What are the official names of this protein?
MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein.
What is the protein family that this protein belongs to?
Belongs to the MET18/MMS19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GH33_ARATH
Sequence: MTVDSALRSPMMHSPSTKDVKALRFIEEMTRNVDFVQKKVIREILSRNSDTEYLKRFGLKGFTDRKTFKTKVPVVIYDDLKPEIQRIANGDRSMILSSYPITEFLTSSGTSAGERKLMPTIDEDMDRRQLLYSLLMPVMNLYVPGLDKGKALYFLFVKTESKTPGGLPARPVLTSYYKSEQFKRRPNDPYNVYTSPNEAILCPDSSQSMYTQMLCGLLMRHEVLRLGAVFASGLLRAIGFLQTNWKELADDISTGTLSSRISDPAIKESMSKILTKPDQELADFITSVCGQDNSWEGIITKIWPNTKYLDVIVTGAMAQYIPMLEYYSGGLPMACTMYASSESYFGINLKPMCKPSEVSYTIMPNMAYFEFLPHHEVPTEKSELVELADVEVGKEYELVITTYAGLNRYRVGDILQVTGFYNSAPQFKFVRRKNVLLSIESDKTDEAELQSAVENASLLLGEQGTRVIEYTSYAETKTIPGHYVIYWELLVKDQTNPPNDEVMARCCLEMEESLNSVYRQSRVADKSIGPLEIRVVKNGTFEELMDYAISRGASINQYKVPRCVSFTPIMELLDSRVVSTHFSPALPHWSPERRR
What is the function of this protein?
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin.  Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val.  Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys.  Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA).  The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates.
What are the official names of this protein?
Indole-3-acetic acid-amido synthetase GH3.3, Auxin-responsive GH3-like protein 3, AtGH3-3.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: PVK21_PERFU
Sequence: GSSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.1, Pea-PVK-2-like peptide, Periviscerokinin-3, PerFu-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_ALIF1
Sequence: MDDNKKKALAAALGQIEKQFGKGSIMKLGDNRTMDVETVSTGSLSLDIALGAGGLPMGRIVEIFGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVYAKKLGVNIDELLVSQPDTGEQALEICDALARSGAVDVMVIDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGNLKQSNCMAIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAVKDGDEVVGNETRIKVVKNKIAAPFKQAETQIMYGQGFNREGELIDLGVKHKLVDKAGAWYSYNGDKIGQGKANASKFMRENTEVAAELDKKLREMLLTPAEEKPETDAAPEIEENEEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLIT1_CLINE
Sequence: MASLEDGIYRLRAVTTHNPDPGVGGEYATVEGARQPVKAEPSTPPFFERQIWQVTRNSDGQSTIKYQGLNTPFEYGFSYDQLEQNAPVIAGDPKEYILQLVPSTTDVYIIRAPIQRVGVDVEVGVQGNNLVYKFFPVDGSGGDRPAWRFTRE
What is the function of this protein?
Binds and inhibits cysteine proteinases.  Inhibits most strongly papain and cathepsin L, more weakly bromelain and cathepsin B while it is completely ineffective against cathepsin H.
What are the official names of this protein?
Clitocypin-1, Cysteine protease inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I48 family.
What are the subcellular locations of this protein?
Note=Not secreted.
Protein: RL16_CHLAA
Sequence: MLLPKRTKYRKMQKGRSPGLSYRGNNVVFGEYGLMALEPSWISSRQIEAARRAITNYVKRGGKVWIRIFPDKPVTRKPAETRMGGGKGSVDHWVAVVKPGRIMFELAGVREDVAHEALRRAAQKLPIKCKVIDREEQGTMAKPEEVSSESE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: THIM_METMP
Sequence: MDFVAKNLTKLRETNPLVQNITNYVVMNSTANSLLALGASPVMAHAMDELEEMVSIASALVVNIGTLDEYWIPSMEKAAKIASDLKKPIVLDPVGAGATKLRTKTALKILDFADISVLRGNFGEIAAVLGEHGKTRGVDSAAYDSNEAIELSKNAAKEFNTVSAVTGPVDHVSNGKEIYSISNGHSMLSKVTGTGCATTSIIGAFSAVDDPLKAAVSGLVVYGISAEMAFTEAPYPGTFQAKVYDWLYRIDEKLVLEKAKVNKFEI
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: AAPAT_NITEU
Sequence: MKLSQRVQAIKPSPTLAVTAKAARLKAEGKNIIGLGAGEPDFDTPLHIKDAAITAIRNGFTKYTAVGGTASLKQAIISKFKRENSLEFMPGEILVSSGGKQSFFNLVLATIDPGDEVIIPAPYWVSYPDIVLIAEGKPVFIDTGIEEKFKISPDQLEKAITPRTRMFVVNSPSNPSGSVYSLEELQALGAVLRKYPDILIATDDMYEHILLSGDGFVNILNACPDLKARTVVLNGVSKAYAMTGWRIGYCGGPAAIITAMENIQSQSTSNPNSIAQVAAEAALNGDQSCMVPMIEAFRERNQFLTNALNSIAGIHCLLSEGAFYAFVDVRQAISRLNTQQILQNSSDIAFCNYVLEKAEVAAVPGSAFGCEGYMRLSFATSMDNLQEAVKRIASLLS
What is the function of this protein?
Catalyzes the reversible conversion of aspartate and 2-oxoglutarate to glutamate and oxaloacetate (PubMed:24302739).  Can also transaminate prephenate in the presence of glutamate, with lower efficiency (PubMed:24302739).
What are the official names of this protein?
Aspartate/prephenate aminotransferase, AspAT / PAT.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_CAMC5
Sequence: MTAKVLKRKLALRIKRKRRIRGKISGVATTPRVSIFKSNRTIYVQAIDDVTATTIAAADGRKLGIKANKEGAAILAKEFASVLKAKKIDTAVFDRNGYLYHGVIAAFADALRENGIKL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL17_TROWT
Sequence: MPKPSRGPRMCSGPDHERLVLANMSASLFLNKKLRTTEARAKRLRPFAEKLVTLSKRGGLHSRRRALSILRNKAALHELFTNIAPLVEDRNGGYTRITKVGFRSGDGAPMALIELILEPVSARTRGTDTLPDTVTDTGPDSAPDPVPGSEPGSAAGDLPDADTAPADPGESSSNQRVIR
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GRPE_SYNPW
Sequence: MSGDASTPEQDPAQVVADGQQPVETPNDPVETPSASDPGSAAEVSPQTGNNEARLEQLEREHTTLRDEHDVLRGQYMRIAADFDNFRKRQSRDQDDLKIQLTCSTLSEILPVVDNFERARQQLDPQGEEAQALHRSYQGLYKQLVDVLKQLGVAPMRVVGQEFDPTLHEAVLREPSDAHPEDVVIEELQRGYHLNGKVLRHAMVKVSMGPGPQDGASSQPAEAPAADAPAEDSGSGDGNG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACM5_SAIBB
Sequence: MEGDSYGNATTINGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPPDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSVSVTKAEKRKPAHRALFRSCFRCPRPTLVQRERNQASRSSSHRSTSITGKPSQATGPSTNWAKAEELTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEEAEETFVKGQTDKNDCDSPDYFLSPAAAHRPKSQQCVAYKFQLVVKADGTQETNNGCHKVKIMPCSFPVAKEPSTKGLSPNLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVALWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCQWKKKKVEEKLYWQGNSKLP
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is Pi turnover.
What are the official names of this protein?
Muscarinic acetylcholine receptor M5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: DNAL4_BOVIN
Sequence: MGETEGKKDEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS
What is the function of this protein?
Force generating protein of respiratory cilia.  Produces force towards the minus ends of microtubules.  Dynein has ATPase activity (By similarity).
What are the official names of this protein?
Dynein axonemal light chain 4.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: BM8X_BOMMX
Sequence: MKCFAQIVVLLLVIAFSHGAVITGACDRDVQCGSGTCCAASLWSRNIRFCVPLGNNGEECHPASHKVPYNGKRLSSLCPCKSGLTCSKSGEKFQCS
What is the function of this protein?
Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia.  Also potentiates capsaicin-induced TRPV1 current when tested on DRG neurons.  At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12.  In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal (GI) smooth muscle (nanomolar concentration) and rabbit aortic rings (PubMed:12628381).
What are the official names of this protein?
Prokineticin Bv8-like peptide 2, Bv8-LP2.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DTPB_ALIFM
Sequence: MDNKVSILNQPKPFKMIFFIELWERFGYYGLQGILAVYFVDKLGFSMQDSFVTFGAFAALVYGLVSVGGYVGDYVLGTKRTMVFGAVVLALGYFLMGFSILNPNFIYVALGAIAVGNGLFKANPSSLLAKCYEKGDSRLDGAFTLYYMSINIGSLVSLSISPVIANNYGYEYAFIICGLGLIASLFSYFSLRSTVQGIGSEPDALPLNKTKALIVLIGTIASTLVCAWLLQNIMMANLALGLIGVGVVGFFLKETFKEVGEQRNKMIVAFILMLQAIIFYVLYAQMPTSLNFFAINNVHSELFGMDINPVSLQALNPFWVIFCSPILAYLYTYYGNQNKDLSMPGKFTVGMFMCAFGFLSVAAAGNWFADQAGMVSVWWMVLVYLFQSLGELMISGLGLAMVASLVPQRLMGFTMGAWFLTQAASFIIGGYVATFSATPEHLTDPLDTLPVYTELFQNIGFVTLAVAIVMAITAPKLNKMMTSSQPEDAELVEQP
What is the function of this protein?
Proton-dependent permease that transports di- and tripeptides.
What are the official names of this protein?
Dipeptide and tripeptide permease B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TUG1_MOUSE
Sequence: MARPPPLPGLVGRRSGRAVDRAIGWRLFLLLWHPALGAQARPPRRAPGGRWRSRRVFLLVRRTRAAAYAFAIRRGVVRVVGGGGQLRPAPGEAAGEAGVAGAGLEAWRHPSGPARTQLEGQEGAGGWLVVGFLLCLFLLMPP
What are the official names of this protein?
Taurine up-regulated 1 protein.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: PHSG_CHLTR
Sequence: MYFDRTKINVESMKQAILERVYCGVVQTPQSASTRDIFTAVAKTVLEWMAKGWLKTQSSYYDNDVKRVYYISMEFLLGRSLKSNLLNLGLLDLVKEALFDLGYDFDQLVEMEHDAGLGNGGLGRLAACFLDSMATLEIPAYGYGLRYDYGIFDQKIENGFQVESPDEWLRYGNPWEICRGEYLYPVHFYGKVKHSIDSRGRDVAELVDSQEVLAMAYDVPVPGFNNDAVNSLRLWQAQSRHGFEFSYFNHGNYIRAIEDIALAGNITRVLYPNDSISEGQELRLKQEYFLVSATIQDILRRYTKTHLSLDKLSEKVSVQLNDTHPALGIAEMMRLLVDREELDWDVAWDATTKIFNYTNHTILPEALERWSLDLFSKVLPRHLEIIYEINARWLAKVSQKYPGDNDKRRALSIIEEGSSKFVNMANLAVVGTNKVNGVSTFHSQLIKSTLFKDFVEFFPDKFINVTNGITPRRWLALSNKKLSSLLNRTIGTEYLTNLTHLHKVIPLAEDSGFREEWRNIKIQNKEELAARIYKELGVTVNPQSIFDCHIKRIHEYKRQLMNILRVIYFYNEIRNGSGEIVPTTVIFGGKAAPGYAMAKLIIKLINNVAAVVNNDPKVNDQLKVIFWPNYRVSLAEAIIPATDLSEQISTAGMEASGTGNMKFALNGALTIGTMDGANIEMAEHIGKEHMFIFGLLEEEISELRKEYYPQGICNANPTIQEILDMIAQAKFSQEDKDLFKPIVNRLLNEGDPFFVLADLEAYINTQNRVASLFKQPEEWTKKSIYNVGGIGFFSSDRSIAEYASNIWNVSRPTS
What is the function of this protein?
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism.  Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.  However, all known phosphorylases share catalytic and structural properties (By similarity).
What are the official names of this protein?
Glycogen phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
Protein: SYN_PHOPR
Sequence: MTYAPVTDVLSGKLAVDSEVTVRGWIRSRRDSKAGISFLAIYDGSCFDPIQAVVPNELNNYQEEVLKLTTGCSVEVTGKIVESPAKGQDFELAATEVKVVGLVEDPDTYPMAKTRHSIEYLREVAHLRPRTNIIGAVARVRNCLSQAIHRFYHEQGFFWMSAPLITASDCEGAGEMFRVSTLDMANVPMTDAGEVDYDKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSNTSRHLAEFWMVEPEVAFADLDDAAKLAEDMLKYVFKAVLEERRDDLEFFAQRINKEAITRLEQFVTSDFAQVDYTDAIQILQDSGRKFEFDVEWGIDMSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGSQREERLEHLDKRIAEMGIDASHIEWYRDLRRYGTVPHSGFGLGFERLVTYVTGMQNIRDVIPFPRAPRSANF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_HERAR
Sequence: MQRIMLRAKIHRAKVTQADLHYEGSCGIDADLLEAADIKVGEKIELYNINNGERFSTYAIQGARGSGEISLNGAAARCAHLGDLMIICTYGPMTDEEIATYTPKIVFVDEDNHFAGMKK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_CUPMC
Sequence: MAIEGVLNEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDMDRFGVIFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALIYGVIQLQNKIKRTNTIARKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROD_GEOTN
Sequence: MAISKGAINVRSIFIGGEEPCICAPVVGVDAEQVLAETRQISAKKPHLIEWRADFFNGIHDDRQVVATAKEIRTIAGDIPILFTVRSEREGGRPIPLTEEEKMRLFETVCQSGAIDLLDYELVHEPYVATVRQLSRQYGVRLILSYHNFDFTPAKEELVAKMRQAGKYGADIAKVAVMPKSLQDVLVLLQATEEARQELPIPLITMSMGGLGAITRLAGGLFGSAVTFAVGQQSSAPGQIPIEEVKDVLSVIMKYSQ
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: ANLN_MOUSE
Sequence: MDPFTEKLLERTRARRENLQRKMAERPTAVARSAPHAKRGREPLSEASNQQQPLPGGEEKSCTKPSPSKKRCSDKIEVGAPDLENTEPIDVAKPCSPMPAPRQAKPPAPAAISESVAAPAALLSADRGLNSGSEASATSSVKTRMQRLAEQRRHWDSDLTDDVSESSYFAPVPTEDKAASPSKPPISNASATPVGRRGRLANLAATICSWEDDVSHSSAKQNSVQEQPGTACLSKSSSASGASASINSSSVQQEATCCSPRDGNASVRKDPSSNAAHGPLLSASVSSSVKASSPVTAATFITENREAQNPELLHKTASPLKTEARKPCEKPTLSQGAQPKEEANREVCLQSQSKDKLATPGGRGIKPFLERFGERCQEHSKESPSYRASHKTPNITPNTKAIQERLFKQNTCSSTTHLAQQLKQEREKELACLRGRLDKGNLWSAEKNEKSRSKHLETKQEVHCQNTPLKKHQTVASTPLTSVTDKVAENEPAVKLSSTEPAGSTESEMTKSSPLKITLFLEEEKSLKVASDLEVEQNTEAVREVEMSVDDEDINSSRVINDIFSDVLEEGELDVEKSQEEMDQVGAENSEEQEDALNISSMSLLAPLAQTVGVVSLENVISSPPSELRDSNLSAASPKPGKFQRTRVPRAESADSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLGEKKNVFSGQVNIKQKMQELNNDINLQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATEKRALLIDELNKLKSEGPQRRNKTSVISQSEFAPSKGSVTLSEICLPLKADFVCSTAQKTDASNYYYLIMLKAGAEQMVATPLASTANSLSGDALTFPTTFTLHDVSNDFEINIEVYSLVQKKDSLGPDKKKKASKSKAITPKRLLTSITSKSSLHSSVMASPGGLGAVRTSNFTLVGSHTLSLSSVGDTKFALDKVPFLSPLEGHICLKISCQVNSAVEEKGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDERRKNPIGRINLANCISHQIEPANREFCARRNTLELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVIVDIRLWQPDACYKPVGKP
What is the function of this protein?
Required for cytokinesis.  Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.  Plays a role in bleb assembly during metaphase and anaphase of mitosis.  May play a significant role in podocyte cell migration.
What are the official names of this protein?
Anillin.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell projection, bleb. Note=Mainly found in the nucleus during interphase. Colocalizes with cortical F-actin upon nuclear envelope breakdown in mitosis and subsequently concentrates in the area of the prospective contractile ring in anaphase. This pattern persists until telophase, when the protein becomes concentrated in the midbody.
Protein: GPMB_PHOLL
Sequence: MLQVYLVRHGESEWNAARRIQGQSDSPLTETGEHQARLVAQRVKSESITHIITSDLGRTRRTAEIIAKVCGCEIILEPRLRELHMGVLERRNIDSLTSEEEKWRKKVLDGTPGGRIPKGESMDELAVRMRAALENCRNLPVGSRPLLVSHGIALGCLVGTILGLPAHAERRLRLRNCSLSRVDYQHSPWLASGWIVETAGDITHLDTPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: DPO3B_MYCSM
Sequence: MATTTAGLTDLKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALPALPEETGVIASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVRELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDGNQVHLALGSGASVGKDGLLGIRSEGKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQIRMEFSDDTLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRPAGEDDGANGGSGPFPAAKTDYVYLLMPVRLPG
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_PYRHO
Sequence: MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLVSAHTRELIRDFGWKGHCGNTPSAYLLGLLIGYKAKKAGIEEAILDIGLHPPVRGSSIFAVLKGAIDAGLNVPHSPEIFPEDYRIRGEHIAEYARMLKEQDEDRFRRQFGGYLEKGLDPEKLPEHFEEVKARIIEKFESEGARE
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: IDHC_PONAB
Sequence: MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (By similarity).  Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (By similarity).  May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity).
What are the official names of this protein?
Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, IDH1, Cytosolic NADP-isocitrate dehydrogenase, IDPc, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.