PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_CHLTR
Sequence: MGVKEIVSNRKAFHHYEVLETLDAGIVLTGTEIKSLRDHGGNLGDAYVTISKGEAWLLQSSIALYRFGNINNHEERRKRKLLLHKYEIHKLDARISQKGLTVVPLSFFFSKGFVKVRIGCCRGKKAHDKRQSIIEREKNRELAAAMKRSYR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: NODA_BRAEL
Sequence: MNIAVSPSAEEPSARTQVQWSLRWESELQLADHAELADFFRKSYGPTGAFNAQPFEGIRSWAGARPEMRVIGYDAHGVAAHIGLLRRFIKIGGVDLLVAELGLYAVRPDLEGLGISHSMRVMYPALQELGVPFGFGTVRPALEKHLTRLVGRRGLATLMPGIRVRSTQADVYPNLSPIRIEDVLVVVFPVGRSMGEWPAGTIIDRNGPEL
What is the function of this protein?
N-acyltransferase required for nodulation.  Acts in the production of a small, heat-stable compound (Nod) that stimulates mitosis in various plant protoplasts (By similarity).
What are the official names of this protein?
Nodulation protein A.
What is the protein family that this protein belongs to?
Belongs to the NodA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN18A_HUMAN
Sequence: MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPTSNPQTSNNCKNFLTEVLLC
What are the official names of this protein?
Ankyrin repeat domain-containing protein 18A.
Protein: RL1_YERPP
Sequence: MAKLTKRMRVIRDKVDVTKQYDINEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFAQGANAEAAKEAGAELVGMDDLADQIKKGEMNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDSDKLKENLESLVVALKKAKPATAKGIYIKKISLSTTMGAGVAIDQSGLTAVVN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: XERC_OCEIH
Sequence: MNQLELYIDTFVEYLQIEKNASPYTVKYYRNDLEIFADFLRSEGLSHIANVTYKDVRIFLTSLYEQELSRRSVSRKISTLRSFYRFLEREGYVEGNPFVQLHLPKTSKPVPGFLYQEELDKLFEVNDITTPLGQRDQALLEMLYGTGIRVSECQNLRLQDIDFAIGTIFVRGKGRKERYVPFGSFAEIALETYLQEGRTKLLEKSNSDTEFIFLNSRGGHLTNRGIRTILNKIVERASLTVHVHPHKLRHTFATHLLNEGADLRSVQELLGHESLSSTQIYTHVTKDHLREAYMKSHPRANGNKS
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XHLA_BACSU
Sequence: MQQEADVNVFQQDLADMKGEHKALEQRVSALERVSDRQDQQIMTLNEKLNKIEENTTWIKRTITGAIITAVSTGIIGGAIAIMYSLLQH
What is the function of this protein?
Associated with cell lysis upon induction of PbsX.
What are the official names of this protein?
Protein XhlA.
What is the protein family that this protein belongs to?
To B.licheniformis xpaF1 and xpaL1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACCD_OENOB
Sequence: MTWFNRLKDYSKQQTDKLLNRYLTQIPSGIWRECPRCHSRFYYRRFGNFDVCPECGYGFRLTARKRLRMLTKDAVEWDADLVTKDPLSFPGYSEKLQRAQKITKLNESVWTGLALLDKRSVALGIMDPYFIMGSLGMITGEKLARLFERATLHELPVILFTASGGARMQEGIHSLMQMSKVTAAVNRHRQAGLLYIVVLTDPTTGGVIASFAMEADITIAEPKALIGFAGRRVIEQTVKQKLPADFQSAEQLQKNGFVDEIVPREHLTEELKLLLDMNQSNAWRANHDK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_ECO45
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLIKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_VIBVY
Sequence: MAVQQNRKTRSKRGMRRSHDALTTAALSVDATSGETHLRHNVTAEGYYRGKKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: Y591_MYCPN
Sequence: MANSLRNVNDYDPFKYRPSYFDLEAPTESFALGKFVDAIEVKQMALDAFSESSMVSIATSQLPKTAYTATSFIESEYYSFPYLFNDQKYYWDYFDYKIPAADFAVLELELDLNNQQDQQIKDHFIDPAIKAYKQLGDSTGLFATKPLTEYQNDTHYLLGYPVVPTDHTQLWECKQGAERFSYGYFYSNMARLTKNLRQGDPNAGSKTHIEYSNELLDKDSMDQGIVRFSTFLGANINYHDYDYRQQGYGLTLTDTNLPGGSSGSLVFNQDKKISSIYSAATESDSVGYAQLLRTPRDVNGISVVSQSYDLIFGDSNTKRYYAMFAKKQQTHLYSEILKSTDEQYRYVVDKQFN
What are the official names of this protein?
Uncharacterized protein MPN_591.
What is the protein family that this protein belongs to?
Belongs to the MG067/MG068/MG395 family.
Protein: KPYK2_SYNY3
Sequence: MQTSPLPRRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQIAFELNQPVGILQDLQGPKIRVGKFLNDAGSVQLKNGDPYTLTSRPVECTETISSISYEYLADEVPSGARILLDDGKLEMLVEEVDTVARDLHCRVIVGGTLSSNKGVNFPGVCLSVKAMTDKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAAAGKSVPVIAKIEKHEAIKDMQAVLEKCDGVMVARGDLGVELPAEDVPILQKKLIATANRLGIPVITATQMLDSMVNSPRPTRAEVSDVANAILDGTDAVMLSNETAIGKFPVEAVAIMAKIAERIEQEDINPSQAEASRTSIPNAISSAVSQIAETLNAAAIMSLTKTGSTARHVSKFRPKTPILAVTPHVDVSRQLQLVWGVKPLLVLDLPSTSQTFQAAINVAQENHFLRDGDLVVMTAGTLQGVAGSTDLIKVEVVKAILGRGVGIGQGAVSGRARVASRPQAIAQFTQGEILVVPSTNADCVDMMRRAAGIITEEESLTSHAAIIGLRLGVPVIVGFKGATQKIRDGAIVTIDAQKGLIYSGALPPVSKG
What are the official names of this protein?
Pyruvate kinase 2, PK 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: PROA_HAHCH
Sequence: MDINAYMREVGSEARSASRLIAKADTGVKNKALIATAEAIDAAREELMAANAKDLESGRANGLDAALLDRLELTPARIDAMIKGLHQVAALPDPVGEITGLNYRPSGIQVGKMRVPLGVVGIIYESRPNVTVEAASLCLKSGNATILRGGSEAIHSNQAIAACIENGLKTAGLPASVVQVIKTTDRAAVGELITMPDYVDVIVPRGGKGLIERISREARVPVIKHLDGVCHVFIDRDADLNKALTIAVNSKTQRYGTCNTMETLLVDAPVAATILPQLAQAYAEKGVELRGCERTREILPQALSAVEADWSEEYLAPILAIKVVENLDEAIAHINHYGSHHTDAIVTESYSKGRRFLTEVDSSSVMINASTRFADGFEYGLGAEIGISTDKIHARGPVGLEGLTSQKYVVLGDGHIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN5_SCHPO
Sequence: MNNQLENVFRFDEEKERAKIRESPWKHDPEFFRSVKISAVALLKMLRHVSQGMPLEVMGYVQGKVEGASLIILDSFALPVEGTETRVNAHEEAQEYSVQYHTLCKSVYRHENVIGWYHSHPNYGCWLSGVDVETQRQNQKYQDPFVAVVLDPKRSLESPYVNIGAFRTYPVGNDGSIRTKSRHHPSVLFKNLPSSKIEDAGAHAEAYYSLPITYFHSKAEKKVTEFLRNRNWSRSITECSILQNNEFLHDSEKLIDHLIHETGNNELPVASAYEQSKACCNELSTFLSQIDVQDKLFKE
What is the function of this protein?
Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
What are the official names of this protein?
COP9 signalosome complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PPARG_PIG
Sequence: MGETLGDSLIDPESDAFDTLSANISQEVTMVDTEMPFWPTNFGISSVDLSVMDDHSHSFDIKPFTTVDFSSISTPHYEDIPFPRADPMVADYKYDLKLQDYQSAIKVEPVSPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
What is the function of this protein?
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.  Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase.  It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.  Key regulator of adipocyte differentiation and glucose homeostasis.  ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer.  Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses.  Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of BMAL1 in the blood vessels.
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner. NOCT enhances its nuclear translocation (By similarity).
Protein: URE2_PSESM
Sequence: MIPGQYQIQPGDIELNAGRRTHSLTVANSGDRPIQVGSHFHFFETNDALTFDRAASRGMRLNIPAGTAVRFEPGQSREVELVDLAGLREVYGFAGRVMGALD
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MYOFO
Sequence: MTNIRKSHPLLKIINNSFIDLPAPSSISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFSSVTHLCRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYMYTETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIISAMVMVHLLFLHETGSNNPTGIPSNTDMIPFHPYYTIKDILGLLLMIMVLLMLVLFSPDMLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVVALVLSILILAIMPLLHTSKQRSMAFRPLSQCLFWLLVADLLTLTWIGGQPVENPYIIIGQLASILYFSIIIILMPLISLVENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYL_DICNV
Sequence: MQDTYQPAQIEAAIQQQWANEERFKAVVNPQKEKFYCLSMFPYPSGKLHMGHVRNYTIGDVISRYQRMLGKNVLQPMGWDAFGMPAENAAMKNQVAPAQWTYQNIAEMKKQLQSLGFAIDWSREITTCRPDYYRWEQWLFTRLYQKGVIYRKLGAVNWDPVDQTVLANEQVIDGRGWRSGAIVEKREIPMYYFRITDYAEELLNDLEQLDGWPERVKMMQRNWIGKSRGMTIRFPIEPESQKGLSAENAQFLQIYTTRPDTIFGVTFLAVAAEHPLALAAAEDNPALRQFMTECKTGSVAEADLATMPKKGMATGRFVTHPLTGKRLPVWVGNYVLSGYGDAAVMGVPAHDERDFHFAHQYGLPIVQVIQTEKDLPAFNADSWQEWYGDKEEMHVIASDDCNGLNYDQAFEKLSEKLAALNLGEPKTQYRLRDWGISRQRYWGCPIPIIHHDDGEALADTLPVVLPEDKIPDGGGSVLAQSPDYYECRFQGKAARRETDTMDTFVESSWYQFRYMSPHYQKGMLDPEEVAYWQDVDQYIGGIEHAILHLLYARFFTKLLRDEGLVHTDEPFKKLLTQGMVLAGTWYREQEHGSKIWFNPADVQVKTDDKGRIIGGVLLSDGKPVQYGGMEKMSKSKNNGVDPQALIKTYGADTARLYTMFTAPPEASLEWSESGVEGAYRFLRRLWAYCYEFRHSIAKPSEVVPLNEKHQNIRREIHEQLRAARFDYERNQFNTVVSAGMKLFNCLNEIEPDYDALRREGVRILLLILSPIVPHITETLWQALDFSGVISDQALPEVDETALKQDNMTLVVQINGKRRGEISVATDAAQQNIIDCALADERFAPYLAGLTVQKTIYVPKKLVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGMD_DICDI
Sequence: MKIILILVLVLVVSINALNNQFLHISDVHYSSAMNSLLYNASVMCIGPTVTKEFDHKEHEDLIEDTERLNLPTNGLYGRYGCDTNQLLLSEVISEMLNVNSNPDFIIYTGDGAGHGLPNGPWSESQSTLAKSLYGAYPNTQFIPTIGNNDVFPDYNSQCNDSNLQFLYETWAQWIPTNQVSSFLYRGSFVVSPVSGLTIISLNTILYSVKNKNTFSTPQDPCGQFAWLEQQLIAAKQAGNSVYIIGHIFPGLDPFYLQGTWKSQYQTAFFNITSDYQTTITAGFFGHIHRDEIRSIQFDNPSLTNNHYFPMFIGSSITPVYFNNPTFKQFTYDSQSKNITDITAYFSDVYISNLKGHMNWTEEYDFVSIYDIDNQYGIGGDQLNSLMERMVSSNSIFNNYDNFRSGSYLSDSPSMTCLINAATIDELNACTYIAANVA
What are the official names of this protein?
Sphingomyelinase phosphodiesterase D, ASM-like phosphodiesterase D.
What is the protein family that this protein belongs to?
Belongs to the acid sphingomyelinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PPR7_SCHPO
Sequence: MRNCVSPLLFAWTKHLRLREFKIPFPNRLVVRSLNQLSVHHEKVTGCRPRQASSDELHKYSKSASNEAFLSSFAENQLFHKCLPSSAGAVLSENDLMYIIRKVSEVYADNKTEKVTVPFDKHKNPFLIYVKKRFAECFDKNPDLCLIVYSKLEVETLAKITPIWINVAKKNKKEDFLVELCLRFLERFRSCNLTEQAILYQNFRENWWSNIKLPQNLKSLYVELCLVYHFHNSHLGMDSSTVSNLKRFCFSESLGHIFAPLRFQNQQLPLQHVYAFLFSIAYRDNQVDTAHFLYKQWSRAGMGPLPKDAFIKFVQLLSKNRNWVLMRDIVQLEEYNSYLLDHRIVSAFLKPLSEKGNYKDILSLISVWQHSVWRPSLAYLQVVYSFSMRALLVNRQYSSAFAFFWKIDPYIRNERLVSQMLQAASQLHYHDLILYVINTYYSGNIMKNLGNKDLICITQSSPPCNISGIKPGSLKLSPTTNTVLAKSICYWLNDAMALLFLLENQLNCKHSLFQRKSLIILLNGILNCPHSSYDLQFRAVSLLTGRIRLNVDFEVSVLASQLVFFVKHRDFKRTLITMKAISKLQKNFDVRIWNYWLVALIQQKLYSRAVKVYSKLICSSAVRNDTTRSLIRLIPKSYFKSYPLLKESETEKKTNSAL
What is the function of this protein?
Mitochondrial RNA-binding protein required for the stability of the atp6 mRNA.
What are the official names of this protein?
Pentatricopeptide repeat-containing protein 7, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRPF_SYNWW
Sequence: MTRVKICGIRSLEEAIAAREAGAWAIGQVFAPSPRRLEVDIAAAINRELGQSILKIGVFVNEEAENLRRIVASCRLDMVQLHGDEEPAYLEEVSVPVIKSFRVRGSLELEQLKRWRPWAYLFDSYHPGVYGGTGESFDWSFLQEIARQERIILAGGLNTENVGRAIHQLRPLVVDVSSGVEYPSGGKDPAKIREFINIVQEQAT
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: THIG_BORBR
Sequence: MTTEDTLTIAGRSYQSRLLVGTGKYQDFAQTRAALDASGTQIVTVAIRRTNIGQNPDEPSLLDFVPPSQFTLLPNTAGCYSADDAVRTLRLARELLDGHDLVKLEVLGDPQNLFPNMPETLKATRTLVDEGFKVMVYCTDDPIQCRMLEDLGAVAVMPLASLIGSGMGILNPWNLRLIIDQSSVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPILMASAMRKAVEGGREAYLAGRVPRKLYSAAPSSPTEGLIAAVK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPA_STAAW
Sequence: MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
What is the function of this protein?
Secreted tyrosine phosphatase that plays a critical role during infection as a bacterial effector protein that counteracts host defenses.  Required for intramacrophage survival.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpA, Phosphotyrosine phosphatase A, PTPase A.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted intracellularly upon bacterial infection of macrophages.
Protein: CREEH_STRDJ
Sequence: MTTRQHTVCVIGAGPRGLSVIERLCAAARAAAPDTAIGIHVVDPHAPGAGQVWRTSQSAHLLMNTVAGQISVFTDASVELTGPLEPGPSLHAWAEALLAGDIPGHYPDQVLDEARALGPDTYPTRAFYGHYLRWAFDRTVAGAPDCVTVTWHRSRAVALDDEAVALATGHPPRQRVTLEDGEVLEHLDAVVLSQGHLPARPTAVEEQFAALAREHGHTHLPPANPADTELECVQPGQPVLLRGLGLNFFDYMALLTTGRGGSFTRVYGRLVYLPSGREPRMYAGSRRGVPYQARGENEKGPHGRHEPLLLTPARIARLQAARGTDGADFQRDVWPLVAKEVETVYYRTLLTARGRGDRAESFQRAFLRALPGTSAEETVLDAYEIGEKDRWDWDRLSRPYQDQEFGSPEDFTAWLLDHLREDVAEARSGNVSGPLKAALDVLRDLRNEIRLVVDHGGLHGDSHREHLDRWYTPLNAFLSIGPPASRIEEAAALIEAGVLHIIGPDLRVDVDRQGFHAHSPLVPGSRISAEVLIEARLPDITLSRTEDPLLRRLLDSGQCATHRIATRNGTWIYTEGVAVTPRPFQLLDAARRPHPRRYAFGVPTESVHWVTAAGIRPGVNSVTLTDSDAIAQAALGAVLEQRDSLERTAA
What is the function of this protein?
Involved in the biosynthesis of desferrioxamine derivatives which have iron-binding properties and may act as siderophores (PubMed:30120394).  Catalyzes the iterative oxidation of L-aspartic acid to nitrosuccinic acid (2-nitrobutanedioate) via N-hydroxyaspartic acid and nitrososuccinic acid (PubMed:30120394).
What are the official names of this protein?
L-aspartate N-monooxygenase (nitrosuccinate-forming).
Protein: RHG21_HUMAN
Sequence: MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGFGFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEEVRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISSSRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQEAETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLARFSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGSLTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
What is the function of this protein?
Functions as a GTPase-activating protein (GAP) for RHOA and CDC42.  Downstream partner of ARF1 which may control Golgi apparatus structure and function.  Also required for CTNNA1 recruitment to adherens junctions.
What are the official names of this protein?
Rho GTPase-activating protein 21, Rho GTPase-activating protein 10, Rho-type GTPase-activating protein 21.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Localization to the Golgi is dependent on interaction with GTP-bound ARF1.
Protein: OL484_MOUSE
Sequence: MAFLHNGNHTAVTEFILLGLTDDPVLRIVLFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASADIGYSSSVTPNMLVNFLVKQNTISYIGCSIQFGSAAFFGGLECFLLAVMAYDRFVAICNPLLYSTKMSTQVCVQLVVGSYIGGFLNASFATVSFLFLFFCGPNIINHFFCDFAPLIELSCSDVRISVLVTSFSAGTVTMLTVLVIAISYTYILITILKMRSTEGRHKAFSTCTSHLTAVSLFYGTITFIYVMPKSRYSTDQNKVVSVFYMVVIPMLNPLIYSLRNNEIKGALRRHLGKKIFSQSNILFY
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 484, Olfactory receptor 204-16.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_METBF
Sequence: MLYTFPWREYMVEEKNNEEIRHLVRIMNTDLKGAKPVEYALTGLPGIGRRTAILIAKGAGVDPTATLGYLPDEEVAKLDRAIGNFEGIVPSWMLNRQKDLATGQDKHLLGTDILLTFREDINNLKKVRAYRGLRHERGLKVRGQRTKSTGRRGSTVGVSRRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.