PharMolix/UniProtQA huggingface dataset:
Protein: LPXA_XANAC
Sequence: MRDSTPLIHPTAVIDPSATLADDVRVGAFSLIGADVQIGAGTEVGPHCSIHGPTRIGRNNRFIGHAAIGGEPQDKKYAGERTELVIGDGNVIREFVTINRGTGGGGGITVVGNDNWMLAYTHVAHDCHVGNHCVFSNNTTLAGHVTVGDYVIISGFAGAHQFCRIGAHAFLGMGALTNGDVPPFTMVGSESLGRPRGINSEGLKRRGFDAERITAIKRAYRTLYVAGLPLADAKLQLAEQAKSSDDVRGMLEFIEAAERPLLR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_RHOOB
Sequence: MRLSPHEQERLLLSYAAELARRRRQRGLVLNHPEAVALITDHLLEGARDGRSVAELMVSGREVLTRADVMEGVPEMLHDVQVEATFPDGTKLVTVHDPIA
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_GEODF
Sequence: MSYCPNTPEDIREMLAAIGKGSVEELFEPIHHTLRAKSFNLPAGISEQELLVKMQELAACDRHLINFIGGGYYDHHIPAVVDHLSGRAEFYTAYTPYQPECSQGTLQALFEYQTAICRLTGMEVSNASLYDGGTALAEAAMMALRITGRNRVVIDASVNPFARQIVATYLKNIGVEMVEIPTSSGSADRSALTEALTGDVAAVMVQNPNFFGSIEDLTAISQAAHAKGALLVTSVYPISLGLIKSPGEMGADIVVGDGQSLGNPLAFGGPSFGFIATTKKYIRNLPGRIIGETIDKEGRRGFVLTLQAREQHIKRHKATSNICSNQSLCALRGLIFLASVGKEGMVELANLNRDKAEYAKERLGSIRGVRVLNRGATFNEFTLELPKDAADVVRTLMEKGIAAGVPLGEYYAGMANCMVVTVTEKRSRGEIEALAEALEASL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: INS1_CONTE
Sequence: MTTSSYFLLVALGLLLYVFQSSFGGEHVCWLGDPNHPQGICGPQVADIVEIRCEEKEAEQGGANNARANTGRTSSLMKRRGFLSLLKKRGKRDEGSPLQRSGRGIVCECCKHHCTKEEFTEYCH
What is the function of this protein?
This venom insulin facilitates prey capture by rapidly inducing hypoglycemic shock.  Intraperitoneal injection of this peptide into zebrafish lowers blood glucose with the same potency than human insulin.  In vivo, when applied to water, this peptide reduces overall locomotor activity of zebrafish larvae, observed as a significant decrease in the percentage of time spent swimming and movement frequency.
What are the official names of this protein?
Con-Ins Tx1, Insulin 1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPG_PHOV8
Sequence: MDLFNYSRRESSEVNIGATPLGGNNPIRIQSMTNTVTMDTEACVEQAKRIIDAGGEYVRLTTQGVREAENLKNINIGLRSQGYDTPLVADVHFNPKVADVAAQYAEKVRINPGNYVDPGRTFQKLEYTDEEYAQEIEKIRARFIPFLNICKENHTAIRIGVNHGSLSDRIMSHYGDTPEGMVESCMEFLRICVAEHFNDVVISIKASNTVVMVRTVRLLVKEMEKEGMAFPLHLGVTEAGDGEDGRIKSALGIGALLADGLGDTIRVSLSEAPENEIPVARKLVDYILTREGHPFIPGKEAPQFNYLSPGRRKTKAVRNIGGDNLPVVIAERLEGSFETNPQFKPDYIYCGGSVPQSRDNNIAYLVDANAWNPEDKNVYPAFNYQQMIELHHTVSDLKFLFLPYMAMNDEVIAALKLHPEVVIIAQSNHPNRLGEYRAMTHELMNEGLENPVVFFQYYQETKAEDLQIKAAADMGALIFDGLCDGIFLYNQGPLSHIVVDTTAFGILQAGRIRTSKTEYISCPGCGRTLYDLESTIARIKTATSHLKGLKIGIMGCIVNGPGEMADADYGYVGAGRGKISLYKKKECIEKNIPEDQAVEKLIELIKANGDYTEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GYS_DICDI
Sequence: MIFGTPNSTFLENRLGSSTGMPFSSATSLNSGVDQMMNELNIQQPTSHTVLFDLSWEVAKKVGGIYTVLKTKAPVTVEEYKSRYALIGPYNASTAPTEFEPLIPGPLSSPIIENMMKKYGIHVHFGKWLVEGYPKVFLIDLHSSMHKLGEWRWDLMSGFEQAGDNETNETIVFGYQSALLLKEFAEANPNDKYIAHFHEWQASVGLILLKKWKVPVSTIFTTHATLLGRYLAAGGVDLYNQMQVLNMDFEASKRGIYHRHWIEKKSAADSHVFTTVSEITGYESEHILMRKPDVILPNGLKLDKFTALHEFQNLHAKYKGVLNEFVRGHFYGHYSDFDLDNTLYVFTAGRHEYFNKGVDMFLDSLAGLNKLLQQSGSKMTVVAFIIMPAATNNFNVESLKGHSYLKDMRRTCNTIVEAMGERLFEATSRGKMISPEELLSQEDLVMLKRRIFALKQKSSGPPVVTHNMINDNDEILQHIRRIKLFNSQEDRVKVIYHPEFLTSTNPLIPLDYTEFVRGCHLGIFPSYYEPFGMTPAECCASGCPSITSNLTGFANYMSRALQDTDSKGIFIVDRRFKSSRETVDQMTQYLWKFTQLDRRQRIELRNATEKLSELLDWRTLGKFYKTARALALERAFPPKPISRSPSPSPSSSLKLSTGLSNQIELQQQQQQQQPQPIGTTINLIPPSSNVSVTPTTTPTTTTTATTATTAPITTPKPNVIPINTGKENITLLSPNSMSSLLSDSLNEFKKQQQQQQQSKTPTTPTTTSTTTTTPSTTAAATNKSVLSNPTPTPSPNTSSFIPTNKGSTATTTTTTATPTPTPSNNTNGKPFNPIEALTKSNSSSNFATTSTASVNTNNGGTNSPVSKSIPIPSSKSLK
What is the function of this protein?
Catalyzes the formation of apha-1,4 glycosidic bonds adding glucose residue from UDPG to the growing chain of glycogen.
What are the official names of this protein?
Glycogen [starch] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 3 family.
Protein: ISCS_RICTY
Sequence: MNQQLKNLTLPIYMDYQSTTPIDPRVMEAMLPYFTTKFGNPHSRSHSFGWEAENAVENARSMIAKLIGADSKEIIFTSGATESNNLVIKGIAKFYGNKKNHIITLVSEHKCVLNACRYLEQEGIKITYLPIKPNGIIDLEILKNAITDQTLLVSVMAVNNEIGVIQPLREIGKICRERSVFFHSDIAQGFGKIPINVNEYNIDLASISGHKIYGPKGIGALYIRKKPRVRVTPLINGGGQERGMRSGTLPTPLIVGFGIAAEISYNEMEKDAQHVNYLFDRFLNNIYSRIPEVYLNGDKDQRYKGNLNLSFAGVEGESIILAIKDLAVSSGSACTSASLEPSYVLRSIGISEELAHTSIRFGIGRFTTEQEIDYAVNLICSKIDKLRKLSPLWEMMQEGIDLKKIKWTAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_MYCLB
Sequence: MKQSLAVKTFEDLFAELSERARTRPTDSATVASLDGGIHALGKKILEEAGEVWLAAEHEPKEVLAEEISQLLYWTQVLMISRGLSLDDVYRKL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_CAMDR
Sequence: VLSSKDKTNVKTAFGKIGGHAAEYGAEALERMFLGFPTTKTYFPHFDLSHGSAQVKAHGKKVGDALTKAADHLDDLPSALSALSDLHAHKLRVDPVNFKLLSHCLLVTVAAHHPGDFTPSVHASLDKFLANVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SLX4I_XENTR
Sequence: MNKLVVKCGNFAVLVDLQVLPQGTSKDTSWFSDHEKEEVCTLVRDTLDSRVKEYLDSRRQPGQLKRKEYTQASPLILKGNRLRIAAYFIKRWVKLRCVVKRQYRELHVFPDRFVVCASQLEPASSVWVTEAAATLKESCSSGTSEYFAQPKGIEMTNLLTTPAQAVLKNIVRKTKITKDISDEAERDSRMSPSLGLADTGKADANNIQKALSKAQPEEKRAEEPNDYINTENSLGLPVPEVENDVNHRQPSEASSQQKPQCAELKTQDLSKHLSRLSDSAKQTQSLRASVMQQKRRRHSSEGKERCKKSCLTSDTFIQQGMQRNEAQVKDLEHVPLASQTDPVRHVSADRGDTLPSKPAAIISVASKQQQGALSLFSNIHTEQSVKAVLAPLLNKDLP
What are the official names of this protein?
Protein SLX4IP.
What is the protein family that this protein belongs to?
Belongs to the SLX4IP family.
Protein: RLME_XANC5
Sequence: MPSRSKSSQRWLKEHFADPYVKKAQAEGMRSRAAYKLEELLQRDRLLKPGMVVVDLGAAPGGWSQQVRKSMGDSGRVVALDILDMPALAGVEFLHGDFREQAVLSQFEAMLGDVPVDLVLSDMAPNKSGMDAVDQPRMMHLAELAMEFADTHLKPGGAFLIKLFQGVGSDDYIRELRRRYEKVTIRKPAASRKRSPEVYALGQGKRVQIK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAME_POLNS
Sequence: MNPILKGVYSPARLGVVALTLFGILGVTGCSTAVDETQRAWMNKIFRPYVPDVVQGNFISSEQYAKLQLGMTREQVRQIMGTPLLASYFHANRWDYVFEFKRSGQTVGKERHVTVFFDGDKVVKFEGDALPTEVELVAEIDNYSKSKRSFWEVITDTNKLPVTPPLQQPEVLVTSKTDNLPAGAAVPAANTSGSFWDFFGSSKKDPDPQSPQLGPGTLNDVPKPADSK
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamE.
What is the protein family that this protein belongs to?
Belongs to the BamE family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SYFA_BORPE
Sequence: MRFEGSNSMTLLVDDLVSQAQERFAAASDAAALENAKARFLGKEGALTVLLKALGKLDPEQKREMGARINQAKQQIEALLNARRAALAQAELDARLASETIDVTLPGRGKAAGGIHPVIRTWERVEEIFRSIGFDVADGPEVENDWTNFTALNNPLDHPARSMQDTFYVDMHDADGLPLLLRTHTSPMQVRYARMHKPPIKVIAPGRTYRVDSDATHSPMFHQVEGLWIAEDISFADLKGVYTDFLRCFFESDDLVVRFRPSFFPFTEPSAEIDMMFTSGPNRGRWLEISGSGQVHPQVVRNFGLDPERYIGFAFGSGLERLTMLRYGVNDLRQFYEGDLRFLRQFNE
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_ECOLU
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y366_HAEIN
Sequence: MKTISKQLSAVIFPFIFSACVSQSASSLNHQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQAQQQFELALNSPNYYHQADTFENIVLCAYSAQKMDIYQQTLEKLRQIDGKRAEKFNSLK
What are the official names of this protein?
Uncharacterized protein HI_0366.
Protein: RL18_BORBU
Sequence: MKKIKEAEQRKLRRKKRIKDKIGRGVASRPRITVFKSNRYFYAQVIDDSKGHTIASISTIEKSLNLGKNIDDVKKLGEVLAKRLKEKNINNLIFDRNGYKYHGLIASFATSLREFGINI
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: BAGP_DROME
Sequence: MLNMESAGVSAAMAGLSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSPNGQMMSVESGAESVHSAAEDVDENVEID
What is the function of this protein?
Involved in the determination of cell fates in the dorsal mesoderm.
What are the official names of this protein?
Homeobox protein bagpipe, Homeobox protein NK-3.
What is the protein family that this protein belongs to?
Belongs to the NK-3 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MGSA_ECO7I
Sequence: MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: Y2897_STRM5
Sequence: MRGRDEETGEFHDKSRSQNRRDALDVLALGEKLVSLTPAQLARLPVPEDLLPHIAECKRITAHIAHKRQLAFLAKHMRREEDATLDAIRDALDANSETGRREVAMMHRAEDWRERLLAEGDKALAALLDDYPQADRQQLRTLVRNAQAEKAKNKPPRAYREIFQVLRTLMLPAALGLKASDDEVEADDTADASDED
What are the official names of this protein?
UPF0307 protein Smal_2897.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: TRPB_CERS4
Sequence: MAEDGINSYMTGPDEQGRFGIFGGRFVSETLMPLILDLEARYEHAKTDPDFWAEMDDLWKNYVGRPSPLYFAPRLTEHLGGAKIYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAETGAGQHGVATATVCAKFGLKCVVYMGAHDVERQAPNVFRMRLLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQSIIGREVRWQLAEQEEGRLPDTLVAAIGGGSNAMGLFHPFLDDPSVRIVGVEAGGKGVDDRMEHCASLTGGRPGVLHGNRTYLLQDADGQILEGFSISAGLDYPGIGPEHAWLHDTGRAEYVSITDAEALEAFQLCCALEGIIPALEPSHALAHVIKIAPTLPRDHIIVMNMCGRGDKDIFTVAKHLGFDMKI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SYGA_SODGM
Sequence: MQKFDPKTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPIAAAYVQPSRRSTDGRYGENPNRLQHYYQFQVIIKPSPENIQELYLGSLREVGLDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECRPVTGEITYGLERLAMYLQGVDSVYDLVWSDGPLGRTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQNLLALEKPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCKKNEN
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_STRU0
Sequence: MSRIGNKIITMPAGVELKNDNNVVTVKGPKGELTREFNKNIEIKVEGTEITVSRPNDSKEMKTIHGTTRALLNNMVQGVSEGFKKELEMKGVGYRAQLQGNKLVLSVGKSHQDEVEAPEGITFTVATPTTIAVEGISKELVGQTAAYIRSLRSPEPYKGKGIRYVGEYVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DNAK_CHLCV
Sequence: MSEQKKSSKIIGIDLGTTNSCVSVMEGGQAKVITSSEGTRTTPSIVAFKGNETLVGIPAKRQAVTNPEKTLASTKRFIGRKHSEVESEIKTVPYKVASGSNGDVVFLVDGKQYTPEEIGAQVLIKMKETAEAYLGEPVTEAVITVPAYFNDSQRASTKDAGRIAGLDVKRIIPEPTAAALAYGIDKAGDKKIAVFDLGGGTFDISILEIGDGVFEVLSTNGDTHLGGDDFDEVIIKWMIEEFKKQEGIDLSKDNMALQRLKDAAEKAKIELSGVSSTEINQPFITMDASGPKHLTLTLTRAHFEKLASTLLERTKAPCQKALADAKLSASDIDDVLLVGGMSRMPAVQEVVKSIFGKEPNKGVNPDEVVAIGAAIQGGVLGGEVKDVLLLDVIPLSLGIETLGGVMTPLVERNTTIPTQKKQIFSTAADNQPAVTIVVLQGERPMAKDNKEIGRFDLTDIPPAPRGHPQIEVTFDIDANGILHVSAKDAASGREQKIRIEASSGLKEDEIQRMINDAEKHKEEDKKRREASDARNEADSMIFRAEKAISDYKDNIPESLVKEIEERIEKVRTVLKEEAPVEKIKDASEELSRHMQKIGEAMQSQSASAAASSAANAQGGPNINTEDLKKHSFSTKPPAGNSASSNSNNENIEEADVEIVDKPND
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FTHS_SHEWM
Sequence: MLTDIEISRQATPQPISDIAKKFGIKKDELSQFGDAKAKVKISILDRVKDNVEGKLVIVTAVTPTPFGEGKTVTSIGLTQGLNAIGRKTCACIRQPSMGPVFGIKGGAAGGGYSQVIPMEEMNLHLTGDIHAVSSAHNLAAAAVDARLFHESRLSADEYTLQSGSAPLNIDPEQILWRRVVDHNERSLRNITVGLGDINGPVHASGFDITAASELMAILALSHDLKDMRKRIGRLVLALDKHAQPITAEMIGVAGAMTVIMSNAIEPTLMQTLTGDPCLIHAGPFANIAHGNSSIIADRIALKFADFVVTEGGFGSDMGFEKFCNIKVRESGKAPDAAVLVVTLKALKANSGLESKQDINLPDQARLEAGFLNLKWHMDNVSQYGVPVVVALNRFPSDTQEELEWLKREVMLAGAFGCEISDAFSLGANGAEALAHKVVEATEQDSDFRLLYSSDASIEAKLLTIAESGYGARGVVLSDEAKAQLEQIKAMGLDNLAVCIAKTPLSISHDPLLKGVPQGFELPIAQLKINAGAGFITALVGKVMTMPGLGVKPGYLNIDINEQDEIVGLA
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RF3_HAEDU
Sequence: MSYPQEVNKRRTFAIISHPDAGKTTITEKVLLYGNAIQTAGSVKGKGSSQHAKSDWMEMEKQRGISITTSVMQFPYNNCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEERTIKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVESILKIRCAPITWPIGCGKLFKGVYHLAKDEMYLYKSGQGSTIQEIQIVKGLDNPELDVMVGDDLANQLREELELVQGASNEFDHQAFINGELTPVFFGTALGNFGVDHFLDGLTEWAPKPQARVADIRTVESAEQKFSGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLKHVRLGKEVVISDALIFMAGDRSQAEQAYAGDIIGLHNHGTIQIGDTFTQGENLKFIGIPNFAPELFRRIRLKDPLKQKQLLKGLIQLSEEGAVQVFRPLINNDLIVGAVGVLQFDVVVSRLKSEYNVEAIYETVNVATARWVECTDAKKFEEFKRKNEQNLALDGGDNLTYIAPTMVNLNLAIERYPDVVFFKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH11_MOUSE
Sequence: MAAAVAAAAAAAAAAASFQVLEMESMETAVAGSASLAAEVRGSGTVDFVTGAGISTLVDTGGSDPGPEAEDFECSTHCSELSWRQNEQRRQGLFCDITLCFGGAGGREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGPEPDTVEAVIEYMYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHMYTLSQLALKAADMIRRNFYKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQMKPTYLTRHVKPERLVANNEVCVKLVAEAVERHALRAENIQSGTLQQPTSQVSLLPRYGQNMDVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAITESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAIEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYSLENEEAVRKIAGQVSDEILESLPPEVLSIEGAAICYYRDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC
What is the function of this protein?
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.
What are the official names of this protein?
Kelch-like protein 11.
Protein: MRAY_JANSC
Sequence: MLYWLNELSDGGDVFNLFRYITFRAGGAFFTALIFGFIFGQPLINALRRKYKDGQPIREVGPAHETKAGTPTMGGLLILAALSLATLLWARLDNPYVWLVLGVTWCFGLIGFADDWAKVSRNSSAGVSGKVRLAIGFVVAFGAALIAAWVHPEELSNQLAMPVFKDVLLNMGWMYVPFVMIVIVGSANAVNLTDGLDGLAIMPVMIAAGTLGVIAYAVGRVDFTDYLDVHYVPGTGELLIFTAGLIGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHEIVLAIVGGLFVAEAVSVIVQVLYFKATGKRVFLMAPIHHHFEKKGWAEPQVVIRFWIISLILALIGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNLJ_VIBVY
Sequence: MSESKQQYLEELKQQLHYHAVRYYVEDNPEIPDAEYDRMMRELMAIEAEHPEWISVDSPSQRVGGVALDSFRQVTHEIPMLSLDNAFSDEELESFLKRAQDRMPSAHIDAFCCEPKLDGLAVSLLYENGVLVQAATRGDGTTGENITENVRTIASVPLKLQGEGWPSRIEVRGEVFMPKVGFEKLNDIARKKGEKVFVNPRNAAAGSLRQLDSKITATRPLAFYAYSVGVVEGISLSSSHYQRFLQLKQWGLPMCPETKLVNGLESVKAFYADILNRRDALPYEIDGVVIKIDDIVIQEKLGFVARAPRWAIAYKFPAQEELTLLNDVEFQVGRTGAITPVAKLEPVFVGGVTVSNATLHNADEIERLGVMVGDTVVIRRAGDVIPQIVSVVKERRKGDENPIVFPTSCPVCHSHVERIEGEAVTRCSGGLVCQAQRKEALKHFVSRKALDVDGLGDKVIEQLVDKEMVETPADLFTLSAGVLTVLERMGPKSAQNIVNALNVAKETTLARFLYSLGIREVGEATAANLARHFKTLEAIQTATHEQLIEVPDIGEVVARHITAFFAEEKNQRVVQALIEQGIVWPPVEELGSEIPQPLAGKVVVLTGTLTQLSRGDAKAALERLGAKVTGSVSKKTDIVFAGEAAGSKLTKAQELGVEIQTEQDLLALL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: URE2_ASHGO
Sequence: MQQEIRNSNTPNTGSGNPVSNLSSALRQVHLGNSNTTTDQSNISIDYTSRAPQQQPLDELSRGAAGGPAAGGGPEGSNMVGASSAAQVTAFGGPSVVDSSRITKFFQNQPMEGYTLFSHRSAPNGFKVAIVLSEMGLNYNTIFLDFNLGEHRAPEFVAINPNARVPALIDHSLDNLSLWESGAIILHLANKYYRETGTPLLWSDNLAEQAQINSWLFFQTSGHAPMIGQALHFRYFHSQKVPSAVERYTDEVRRVYGVVEMALAERREALIMDLDSENAAAYSAGTTPLTQSRFFDYPVWLVGDHITIADLSFVPWNNVVDRIGINIKVEFPEVYKWTKHMMRRPAVIKALRGE
What is the function of this protein?
Plays an important role in the cellular response to the nitrogen source.  URE2 gene plays a major part in the repression of GLN1 and GDH2 genes by glutamine, and is required for the inactivation of glutamine synthetase.  URE2 gene product may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine (By similarity).
What are the official names of this protein?
Protein URE2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: RPPH_RICPU
Sequence: MSNSSKKHLDLPYRPGVGMMILNADNHIFVGKRIDTKISAWQMPQGGIVPGETPSIAAMREMLEEIGSDKGYIIAESKFWYSYDVPSFLIPKLWNGNFRGQKQRWFLIRFTGNNEDININTSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFESLIQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: S35G3_HUMAN
Sequence: MAGSHPYFNQPDSTHPSPPSAPPSLRWYQRCQPSDATSGLLVALLGGGLPAGFVGPLSRMAYQASNLPSLELLIWRCLFHLPIALLLKLRGDPLLGTPDIRSRAFFCALLNILSIGCAYSAVQVVPAGNAATVRKGSSTVCSAVLTLCLESQGLSGYDWCGLLGCILGLIIIVGPGLWTLQEGTTGVYTALGYVEAFLGGLALSLRLLVYRSLHFPPCLPTVAFLSGLVGLLGSVPGLFVLQAPVLPSDLLSWSCVGAVGILALVSFTCVGYAVTKAHPALVCAVLHSEVVVALILQYYMLHETVAPSDIVAAGVVLGSIAIITAQNLSCERTGRVEE
What are the official names of this protein?
Solute carrier family 35 member G3, Acyl-malonyl-condensing enzyme 1, Transmembrane protein 21A.
What is the protein family that this protein belongs to?
Belongs to the SLC35G solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.