PharMolix/UniProtQA huggingface dataset:
Protein: ARGD_STAEQ
Sequence: MSYLFNNYKRDNIEFVDANQNELIDKDNNVYLDFSSGIGVTNLGFNMEIYQAVYNQLNLIWHSPNLYLSSIQEEVAQKLIGQRDYLAFFCNSGTEANEAAIKLARKATGKSEIIAFKKSFHGRTYGAMSATGQKKITDQFGPVVPGFKFAIFNDFNSFKSLTSNNTAAVIIEIIQGESGVLPADSLFMKQLNEYCKQKDILIIVDEVQTGIGRTGKLYAHEHYQLSPDIITLAKGLGNGLPIGAMLGKKNLGHAFGYGSHGTTFGGNRLSLAAANQTLSIINDADLLNDVQSKGQFLIENLRKSLVNKRNVIEVRGVGLMVGIEVTNDPSQVVREAKRMGLIILTAGKNVIRLLPPLTITKKQLEKGIEILTEII
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_BURP1
Sequence: MFSSLYPLARASLFKMDAEDAHHLTLRMLGAAGRTGLACALSPRVPDAPRTVMGLSFRNPVGLAAGLDKDGAAIDGFAALGFGFIEVGTVTPRAQPGNPRPRMFRLPEADAIINRMGFNNSGVDQFVKNVQAARYRGVLGLNIGKNADTPIERAADDYLYCLERVYPFASYVTINISSPNTKNLRQLQGAGELDALLAALKDKQRRLADLHGKLVPLALKIAPDLDDEQVKEIAATLLRHDIEGVIATNTTLSREAVKGLPHADEAGGLSGRPVFDASNAVIRKLRAELGDAVPIIGVGGIFSGEDARAKLAAGAALVQLYTGFIYRGPALVAECVKAIARGEAR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CMR5_THET8
Sequence: MRTRSQVWAQKAYEKVREAAKGEGRGEYRDMALKLPVLVRQAGLSQALAFVDSRGKEAHKALGNDLAQVLGYRDLRELAEAAREAELLQYLRLTREVLAAAEWFKRFAQALIEE
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Part of the Cmr ribonucleoprotein complex (By similarity).
What are the official names of this protein?
CRISPR system Cmr subunit Cmr5, CRISPR type III-B/RAMP module-associated protein Cmr5.
What is the protein family that this protein belongs to?
Belongs to the CRISPR system Cmr5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSA_SHEPW
Sequence: MSDQFSNAQHQLDALGLRCPEPVMMVRKSVRRMDDGETLLIIADDPATTRDIPSFCEFMDHTLIASQTDATPYQYLIRKGL
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_DECAR
Sequence: MLDREGYRPNVGIILCNGRNEVFWGKRIREHSWQFPQGGIKRGETPEEAMFRELYEEVGLLPEHVRILGRTKGWLRYEVPTHWIKREWRGSYKGQKQIWFLLRLVGRDSDVNLRATNKPEFDAWRWNDYWVPLDAVIEFKRLVYEQALNELVRFLDFDRKGPRHKKEQEPFSDVVDSVRSEE
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: CRTC1_MOUSE
Sequence: MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGGSLPNVNQIGSSSVDLAFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTVYLSPPADTSWRRTNSDSALHQSTMTPSQAESFTGGSQDAHQKRVLLLTVPGMEDTGAETDKTLSKQSWDSKKAGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPPFPALTSSSSTGSLAHLGVGGAGQGMNTPSSSPQHRPAVVSPLSLSTEARRQQAQQVSPTLSPLSPITQAVAMDALSLEQQLPYAFFTQTGSQQPPPQPQPPPPPPPVSQQQPPPPQVSVGLPQGGPLLPSASLTRGPQLPPLSVTVPSTLPQSPTENPGQSPMGIDATSAPALQYRTSAGSPATQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAYYEQQMTARQANALSRQLEQFNMMENAISSSSLYNPGSTLNYSQAAMMGLSGSHGGLQDPQQLGYTGHGGIPNIILTVTGESPPSLSKELSSTLAGVSDVSFDSDHQFPLDELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL
What is the function of this protein?
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites (PubMed:29211348).  Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated (PubMed:29211348).  Acts independently of CREB1 'Ser-133' phosphorylation.  Enhances the interaction of CREB1 with TAF4.  Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR.  Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells (By similarity).  In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses.  May be required for dendritic growth of developing cortical neurons.  In concert with SIK1, regulates the light-induced entrainment of the circadian clock.  In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
What are the official names of this protein?
CREB-regulated transcription coactivator 1, Mucoepidermoid carcinoma translocated protein 1 homolog, Transducer of regulated cAMP response element-binding protein 1, TORC-1, Transducer of CREB protein 1.
What is the protein family that this protein belongs to?
Belongs to the TORC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic when phosphorylated by SIK or AMPK and when sequestered by 14-3-3 proteins (By similarity). Translocated to the nucleus on Ser-151 dephosphorylation, instigated by a number of factors including calcium ion and cAMP levels (By similarity). Light stimulation triggers a nuclear accumulation in the suprachiasmatic nucleus (SCN) of the brain (PubMed:23699513).
Protein: PPM1_MYCS2
Sequence: MSVPGEREQGAGEDPATVRPTQRTLVIIPTYNERENLPLIVGRVHHACPQVHILVVDDGSPDGTGALADELALADPDRVHVMHRTSKAGLGAAYLAGFDWGLRRGYSVLVEMDADGSHAPEELSRLLDAVDAGADLAIGSRYVPGGTVRNWPWRRLVLSKTANTYSRFLLGVGIHDITAGYRAYRREVLEKIDLSAVDSKGYCFQIDLTWRAINNGFSVVEVPITFTERELGVSKMSGSNIREAMFKVAEWGIRGRLDRARGVVR
What is the function of this protein?
Transfers mannose from GDP-mannose to lipid acceptors to form polyprenol monophosphomannose (PPM); catalytic activity in vitro is enhanced by Lnt (AC A0QZ13) (PubMed:12427759).  PMM is an alkai-stable sugar donor which adds mannose-phosphate residues to triacylated-PIM2, eventually leading to generation of the cell wall glycolipid lipoglycan modulins lipoarabinomannan (LAM) and lipomannan (LM) (By similarity).
What are the official names of this protein?
Polyprenol monophosphomannose synthase, PPM synthase, Polyprenol-P-Man synthase, Ppm1, Dolichol-phosphate mannose synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACI_KLEPN
Sequence: MPRRTATLEDVARRGRVPADGLRRVLNRPEVVSARTREQVIRAMQALHYVPNRSAQLLAGKAAPSIGLITASVTLHAPSQIAAAIKSHASLHQLEVAIAMPAQADFVALQARLDELRAQHIRGVIVSLPLESATAERLVQDNPDMACLFLDVSPEADVCCVRFDHRDGCGACVRHLWEMGHREFGLLAGPESSVSARLRLASWREALHSLNIARSTTVFGDWSAASGWQKTFELLHLQPRISAIVVANDQMALGVLSALAQLNRSGSQAVSVTGYDDTADSLYFQPPLTTVAQDFDLLGKRAVERLIALMAAPQLRIRELLPTRLIVRQSAWPVAAAEDRQQTLAQLKALVEKL
What is the function of this protein?
Repressor of the lactose operon.  Binds lactose as an inducer.
What are the official names of this protein?
Lactose operon repressor.
Protein: NFUA_SHEFN
Sequence: MITISDTAQAHFVKLLADQPEGTHIRVFVISPGTAQAECGVSYCPPDAAEADDVELPFNGFSAMVDEKSAPFLDDASIDFVTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYIIQSEINPQLASHGGNIMLVEITEAGVAVLQFGGGCNGCSQVDITLKDGIEKQLLDMFPTELTGVRDVTEHEHGEHSYA
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: RIR2H_MYCA1
Sequence: MNRTRSASMVQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLTDDERSYATRLCAEFIAGEESVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHVQVFRMWLDAVGVTDDLHHFLDDVPSYRTIFYEELPDCLNALTIDPSPAAQVRASVTYNHMVEGMLALTGYFGWHKICVERGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLRLIEEGFALYDPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDTFADEDARALAAV
What is the function of this protein?
Probable oxidase that might be involved in lipid metabolism.
What are the official names of this protein?
R2-like ligand binding oxidase, Ribonucleotide reductase R2 subunit homolog, Ribonucleotide reductase small subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
Protein: RS18_SHIFL
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SPEH_CLOBH
Sequence: MKYSGYHLVIDLFGCNFDQLENTEYIIEMLKKLARALDTKIVAKAFHKFHPQGFSGALIISESHITIHTWPEDAYIGIDIFTCSKCFDPRKIVAYLKENLIFKKVEIKEILRGKID
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: RUXF_XENLA
Sequence: MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.  As part of the U7 snRNP it is involved in histone 3'-end processing.
What are the official names of this protein?
Small nuclear ribonucleoprotein F, snRNP-F, Sm protein F, Sm-F, SmF.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: TRHO_OCEIH
Sequence: MESNQEYQVLLYYQYVTIDDPEAFAEEHLRYCKEIGLKGRILVANEGINGTVSGTIEQTTAYMDHMHNDERFHDMTFKIDPHEGHTFKKMHVRPRPELVTLRLEDDVNPLETTGEYLEPKDFYQALQDENTVVLDARNDYEYDLGHFRGAIRPDIKTFRDLPDWVQENKDMLEGKKVVTYCTGGIRCEKFSGWLVKEGFEDVAQLHGGIVTYGQDPEVQGDLWDGQLYVFDERISVPVNRKEHVIVGKDYFDGEPCERYVNCANPECNKQILASEENEHKYLRGCTHECRVTPRNLYVKEHELTGTQVEERLLAIGESLTQEV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: YL743_MIMIV
Sequence: MGTNYYLYFITKDKYRSRELLECHVGYNNILDGINFLGFLVTFMDDLIVYWKFKNLDHKNPDRFREIILVSNTLTLLCRQLINGETVTSIANLYDILKISVQYLGDEYVFKDEYDKIISTSEVIDIFYCENLHTENFLRDSISGFYISTDF
What are the official names of this protein?
Uncharacterized protein L743.
Protein: DMX1B_DANRE
Sequence: MQHYGVNGYSLHAMNSLSAMYNLHQQAAQHAQHAPDYRPSVHALTLAERLADIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQRLKEAGTEGAQDEGKEEAPPVEAQAPPSPLDGRGLTSAPSCELNEEVNVTSPEQSGAESGAEDTTDREDEPLSIKDEIKEAGPPLMTDDSSPSYKPLSPKSDDPLVSPALPSSSGAVAQSNSYASSPLSLFRLQEQFRQHMAATNNLMHYPAFDVTAPSSLPYLGVNVNMASPLGSLPCQPYYQTLTQAQQMWSSPLLQGSGGLPALNSKTTSIENLRLRAKQHAASLGLDTLPN
What are the official names of this protein?
Diencephalon/mesencephalon homeobox protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGA_HALH5
Sequence: MNVLHVASECNPFFKTGGLADVLGSLPKALIKQGINVSVILPKYGHLSDEWQNQLTLKKSFTVSVTWRNQYCGLEQFVDQGVTYYFIDNEYYFKRERLYGYLDEAERFTFFNHAVLSSLPFLDESPDLIHCHDWQSGLIPAYMKTGSVENPVPTVFTIHNLRYQGAFPPDVFRELLHFAPEHFAGLEMDGAINFLKGALVHSDRVTTVSPTYAQEIQTPAFGEGLHGLLHQERGKTRGILNGIDLEDFDPKTDPHVTYPYKHNQMEKRKNKQVIQRLFELPERKDIPLIAMVSRLVEEKGVPLLTQIAGELVTTENVQLAILGTGDPSLEDQLHHLASLHPHQISFKCVFAEPLARKLYAGADLFIMPSRFEPCGLSQMISLRYETVPIVRETGGLYDTIQSYNEEIGEGNGFSFTHYNAHDFLYTIKRALRFYRTEKEWENLLLNIYSSEVGWDVSAKQYTALYEEILGKRKVEA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: ENT2_YEAST
Sequence: MSKQFVRSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQRSYDSVDFFEIMDMLDKRLNDKGKYWRHVAKSLTVLDYLVRFGSENCVLWCRENFYVIKTLREFRHENESGFDEGQIIRVKAKELVSLLNDEERLREERSMNTRNRRANRAARPRPRRQRTRSNPHDSSPSYQDDLEKALEESRITAQEDEQRRRELAQYDDEDPDFQAALQLSKEEEELKQLQELQRLQKQQQSLSQFQAPLQQQQPQQQPAYYDIFGNPISQDEYLQYQYQQDQEQAMAQQRWLDQQQEQQQLAEQQYFQQQQQAAAAASALQQQQTAANMQQQQQQPADFQQPLPTGSNNPFSMDNLERQKQEQQHAQLQRQQEEARQQQEQLKLQQLQRQQQEEAQLHQKRQEEAQLQQQQAQLLQQQAQFQQQQPLKQTRTGNQSISDKYSDLNTLLATGTGIDTFGNTGEARIPAQHTKTGTFINSQGTGYKQVTNEPKNNPFLSNQYTGLPSTNIVPTQTGYGFGNQPQSPPTNSPQQNPTGISYSQPQQQQQPQQQPQYMQNFQQQQPQYAQNFQQQPQYTQNYQQQPQYIQPHQQQQQQQQQQQQQQGYTPDQGVSLIDL
What is the function of this protein?
Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).  Required for endocytosis and localization of actin.
What are the official names of this protein?
Epsin-2.
What is the protein family that this protein belongs to?
Belongs to the epsin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Localizes in a punctate pattern. Found in the actin cortical patches, although the majority is located at the cell periphery.
Protein: HEM3_STAA2
Sequence: MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEIIKRLNEQH
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: MDH_DEIDV
Sequence: MTNKQPVRVAVTGAAGQIGYSLLFRIAAGDMLGKDQPVILQLLEITPALKALQGVVMELRDGAYPLLADVVTSDDPLVAFKDADYALLVGAMPRKAGMERGDLLGANGGIFKPQGQALNQVASRDVKVLVVGNPANTNALIAQQNAPDLDPRQFTAMVRLDHNRAISQLAEKTGQPVSAIKNITIWGNHSSTQYPDLSQATVGGRPALDLVDRTWYEQEYIPTVAKRGAAIIEARGASSAASAASAAIDHMRDWALGTSEGEWVSMGIPSDGSYGVPEGLIYGFPVTVKDGKYQIVQGLEISEFSRGKMDATARELEEERDEIRKLGLIS
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: LEC1_DABRR
Sequence: NQDCLSDWSFYEQYCYKVF
What are the official names of this protein?
C-type lectin domain-containing protein 1, CLP1.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEFL_STAAW
Sequence: MAIKKLVPASHPILTKKAQAVIKFDDSLKRLLQDLEDTMYAQEAAGLCAPQINQSLQVAIIDMEMEGLLQLVNPKIISQSNETITDLEGSITLPDVYGEVTRSKMIVVESYDVNGNKVELTAHEDVARMILHIIDQMNGIPFTERADRILTDKEVEAYFIND
What are the official names of this protein?
Peptide deformylase-like, Polypeptide deformylase-like.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: Y5498_ACAM1
Sequence: MDIKLINIGFGNIVSGNRVISIVSPESAPIKRIISEARDRAQLIDATYGRRTRAVIVTDSGHVVLSAIQPETVAHRFMSNKDTKDSDK
What are the official names of this protein?
Putative regulatory protein AM1_5498.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: SPD11_HUMAN
Sequence: MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS
What is the function of this protein?
Acts as a modulator of the nicotinic acetylcholine receptor alpha-7 (CHRNA7) activity.
What are the official names of this protein?
Putative speedy protein E11.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: SSRP_PECAS
Sequence: MTKKKAYKPGSATIAQNKRARHEYSIEEEFEAGLVLQGWEVKSLRAGKANLSDSYVTFMNGEAYLFGATITPLNVASSHVVCDPIRTRKLLLNKREMDSLFGRVSRDGYTVVALSMYWKNAWSKVKIGVAKGKKDHDKRDDIKEREWKLDKARIMKNANR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: OBG_ELUMP
Sequence: MSFLDRVKIYVKAGKGGDGCLSFRREKFIEFGGPNGGNGGKGGDVYIKTERNLTTLLELAYNPHIEAKNGEKGGTYNKTGVGADDLTIYVPCGTIVKKDGEIIADLTEEGQSVLVAKGGRGGRGNQSFKTHSNTAPRISEIGQPGEEITLYLELKVLADLGLVGFPNAGKSTFLSRVSAARPKIADYPFTTLNPNLGIAMHKKVSFVIADIPGIIEGASEGKGLGHQFLKHIERTRVLLHLVDPMGFKDIDAVESVKVIEKELKTFDRELAKKPRIIALNKADLPEAKEVYNKIVKKYKKHKVFLISAATGEGVDKVLNEIVKVISATPVPNVAISKSTVAVHGVEPLFKIVPLEDGRVQVFGRKIEDMVNMTHFNQLQGVERLRNIFKKIGLEKALIKKGVMPGDIIVVGQKEFEWSGTELDSERAEQPDFEGYKRRTTQAERLEKRRQRRLKKEEK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_PSYA2
Sequence: MTTPAATTDLSALPTLSSELNELNEAQLIEFTSAAEALILQVSDVRLLQDLRVQLTGKKSPLTGWSKQMGKLSNDDKKTYGGWLHEVRSRIQDALTAQQQQLEVVALNAKLASESIDITLPARGGQKGHLHPVTMITQRMQQYFIQAGFNVATGPEVESDYYNFEALNIPSHHPARAMHDTFYFDAHYLLRTHTSPVQIRTMEKNEPPIRIICPGRVYRNDSDQTHSPMFHQLEGLMVTESSTFAELKGLISEFLEAFFAKELTVRFRPSFFPFTEPSAEVDILDDNGKWLEVMGCGMVHPQVLTNCGIDAEKYTGFAFGMGIERFAMLYYGIDDLRLFFQNDVRFLKQFG
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI17C_DROME
Sequence: MEYNRQPCPIRIVEDCGCAFMMGTIGGSLFEFLKGFRNAPTGLQRRLYGGIDLVKMRTPSIAGSFAVWGATFSTVDCALVHYRQREDAWNSILSGAATGGILAARNGIRAMANSALVGCLVLAMIEGAGAAVATINAADKGAGIVIKPQRAQWEAILETIDPKRASSTQDFALAEFERVLDKCRASREPNLLQDIPVKSHERDSKQKPFYSLLDLVKLSQMF
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Probable mitochondrial import inner membrane translocase subunit Tim17 3.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EIF3L_DROSI
Sequence: MYGGDEYATNSEYYDDYAHTGDPQLDMEYERNYYAARMPDNVKYFLINFCQAIKEGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIVDNDKVFLILYKELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFAQYRARLTEKSQDEIQQLCVNHSNEWSILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGDFGKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMMMRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVLREKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQLLVFMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTFKSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKNINI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXC_AZOC5
Sequence: MIDEKFDAIVVGAGMAGNAATLTLARRGLKVLQLERGEYSGSKNVQGAILYADMLEKLVPDFREDAPLERHLVEQRFWMLDDRSHVGLHYRSEDFNEEKPNRYTIIRAQFDKWFSSKVKEAGATVLCETTVTELVQDAYGKVIGVKTDRSGGQIHADVVVLAEGVNGLLGTKAHLRERPKPEHVALAVKEMHFLPRETIEARFNLQGDEGVVIEAAGTISRGMTGMGFIYANKECISLGIGCLVSDFQKTGETPYGLLERFKSHPSVAPLIEGSEVKEYAAHLIPEGGFKAIPQLFGDGWVVVGDAAQLNNAVHREGSNLAMTSGRIAAEAIFQVKSRREPMSAKNLSLYKTMLEESFVLKDMKKYKDLPALLHINSQNFFLTYPQLVSKAMQNFVRVDGTPKVEKEKRTLRAFVEARSWFGLFGDAFRFARAWR
What is the function of this protein?
Could be required for the formation of a functional nitrogenase Fe protein.  Probably accepts electrons from FixA/FixB and reduces a quinone.
What are the official names of this protein?
Protein FixC.
What is the protein family that this protein belongs to?
Belongs to the ETF-QO/FixC family.