PharMolix/UniProtQA huggingface dataset:
Protein: COAE_BORPA
Sequence: MYKIGLTGGIGSGKSRVADMLAEWGASVIDADEISHALTAPGGAAMPAIAREFGPQAVAADGALDRAWMRDLVFREPAARGRLEALLHPLIGLHTEQAAAQARGLYLVFVVPLLVESGRWRGRVDRICVVDCDPATQIARVQKRSGLTEPAIRRIMAAQAARATRLEAADDVIVNDGATSPDTLRARARTLHDRWLALAGAASQPGGKAAGTPE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_NITWN
Sequence: MPKLKTKSGAKKRFKITATGKVKHAQRGKRHGMIKRTKKQIRQLRGTRVLFKTDGDNIKKYFLPNA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: Y1301_ARCFU
Sequence: MKTSLSSLQRGLSEIFAFAYRNYALTKNEFYAIFEMLFWPLVSLISVGLLGEFLYLDREAVASY
What are the official names of this protein?
Uncharacterized protein AF_1301.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL20_EHRRG
Sequence: MARVKRGVTTRARHKKVIKLAKGYRGRSKNCYRVALQRVEKALQYAYRDRRNRKRFFRSLWIMRINAAVRQYGLLYSDFIYGLSLANITLNRKILADMAVHNKDNFKQIVDLTKEALTKSRVG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MT1A_ARATH
Sequence: MADSNCGCGSSCKCGDSCSCEKNYNKECDNCSCGSNCSCGSNCNC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals (Probable).  Functions as metal chelator of copper (Cu) and zinc (Zn).  Plays a role in Cu homeostasis in the roots under elevated Cu concentration.  Functions cooperatively with the phytochelatin synthase PCS1 to protect plants from Cu and cadmium (Cd) toxicity (PubMed:18287486).  Plays a role in Cu homeostasis, specifically in the remobilization of Cu from senescing leaves.  The mobilization of Cu from internal sources is important for seed development (PubMed:24635746).  Confers tolerance to Cd and plays a role in Cd and Zn homeostasis (PubMed:16240177).
What are the official names of this protein?
Metallothionein-like protein 1A, MT-1A, MT-2, MT-Q, Protein LIGHT STRESS-REGULATED 4.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: MRAY_HELAH
Sequence: MLYSLLYGYFNINLFQYLTFRAGLGFFIAFFLTLFLMPKFILWAKAKKANQPISSFVPSHQNKKDTPTMGGIVFVFATIIASLLCASLGNPYVLLGIIVLVGFSFVGFRDDYTKINQQSNAGMSAKMKFGMLFVLSLVVSVLLSVKGLDTFLYAPFLKNPLFEMPTALAVGFWVLVFLSASNAVNLTDGLDGLASVPSIFTLLSLSIFVYVAGNAEFSKYLLYPKVIDVGELFVISLALIGSLFGFLWYNCNPASVFMGDSGSLALGGFIAYNAIVSHNEILLVLMGSIFVIETLSVILQVGSYKTRKKRLFLMAPIHHHFEQKGWAENKVIVRFWIISMLSNLVALLSLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCS1_YEAST
Sequence: MDTSHEIHDKIPDTLREQQQHLRQKESEGCITTLKDLNVPETKKLSSVLHGRKASTYLRIFRDDECLADNNNGVDSNNGGSVTCADKITRSEATPKSVPEGLQVSEKKNNPDTLSSSLSSFILSNHEEPAIKPNKHVAHRNNITETGQGSGEDIAKQQSHQPQVLHHQTSLKPIQNVDEGCISPKSTYQESLHGISEDLTLKPVSSATYYPHKSKADSGYEEKDKMENDIDTIQPATINCASGIATLPSSYNRHTFKVKTYSTLSQSLRQENVNNRSNEKKPQQFVPHSESIKEKPNTFEQDKEGEQADEEEDEGDNEHREYPLAVELKPFTNRVGGHTAIFRFSKRAVCKALVNRENRWYENIELCHKELLQFMPRYIGVLNVRQHFQSKDDFLSDLDQENNGKNDTSNENKDIEVNHNNNDDIALNTEPTGTPLTHIHSFPLEHSSRQVLEKEHPEIESVHPHVKRSLSSSNQPSLLPEVVLNDNRHIIPESLWYKYSDSPNSAPNDSYFSSSSSHNSCSFGERGNTNKLKRRDSGSTMINTELKNLVIREVFAPKCFRRKRNSNTTTMGNHNARLGSSPSFLTQKSRASSHDASNTSMKTLGDSSSQASLQMDDSKVNPNLQDPFLKKSLHEKISNALDGSHSVMDLKQFHKNEQIKHKNSFCNSLSPILTATNSRDDGEFATSPNYISNAQDGVFDMDEDTGNETINMDNHGCHLDSGKNMIIKSLAYNVSNDYSHHDIESITFEETSHTIVSKFILLEDLTRNMNKPCALDLKMGTRQYGVDAKRAKQLSQRAKCLKTTSRRLGVRICGLKVWNKDYYITRDKYFGRRVKVGWQFARVLARFLYDGKTIESLIRQIPRLIKQLDTLYSEIFNLKGYRLYGASLLLMYDGDANKSNSKRKKAANVKVNLIDFARCVTKEDAMECMDKFRIPPKSPNIEDKGFLRGVKSLRFYLLLIWNYLTSDMPLIFDEVEMNDMISEEADSNSFTSATGSKINFNSKWDWLDEFDKEDEEMYNDPNSKLRQKWRKYELIFDAEPRYNDDAQVSD
What is the function of this protein?
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5).  Involved in phosphate regulation and polyphosphate accumulation.  Required for resistance to salt stress, cell wall integrity, vacuole morphogenesis, and telomere maintenance.
What are the official names of this protein?
Inositol hexakisphosphate kinase 1, InsP6 kinase 1, InsP6 kinase KCS1, PKC1 suppressor protein 1.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_AERS4
Sequence: MADQIAISVLGAGSYGSALAISLARNGHPTLLWGHDPAHVAELEHDRCNKAFLPDVPFPADLQLTADLQRAVQAAPVLLLVVPSHVFGQVLSQVKPFLRPDTRIAWATKGLEPDSGRLLQDVARDVLGETIPLAVISGPTFAKELAAGLPTAISVASTHDDFADELSHLLHCGRSFRVYTNPDFVGLQLGGAVKNVIAIGAGLSDGLGFGANARTALITRGLVEMQRLGAALGADAKTFMGMAGLGDLVLTCTDNQSRNRRFGLALGAGKAVETAMAEIGQVVEGYRNTKEVHLLAARCGVEMPICEQIFQVLYQGKNPKEAAIALLSRDKRDE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHCX_BACSU
Sequence: MSEKLDLTRFEKKMVIRNIEEKDIDKIIDLQKDCFPGMEPWKREHLISHLEHFPEGQFCAEFEGEIIGSCSSLLINFDEYDDRHTWQDITDDGYITNHNPDGLNMYGIEVMVHPKYRRMKIGHRLYEARKDLARRLNLKSIIIGGRIPNYHKYAEEMTAREYVEQVTRHQIYDPVLSFQLMNGFTLMRINPNYLPDDTASIKYATLMEWNNVDYLPQQTKRYYKSAFPVRICVIQYEMKKIYSFEEFANQVEYYVDVASDARSDFAVFPEIFTTQLMSFLEERSPSLAVQRITEYTEDYISLFTDLAVKYNVNIIGGSHFVEEEGKIYNIAYLFRRDGTIEKQYKLHITPNERKWWGISAGDQVRVFDTDCGKIAIQICYDIEFPELARIAADKGAKIIFTPFCTEDRQGYLRVRYCSQARAVENQIYTVISGTVGNLPQTENMDIQYAQSGIFAPSDFEFARDGIVGETNPNIEMVVIGDVDLEILRRQRQNGTVRQLKDRRRDIYHIQYKK
What are the official names of this protein?
Hydrolase YhcX.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: DHYS_RAT
Sequence: MEGTPSGAAPSSALAAVLKHSSALPPESAQVQGYDFNRGVDYHALLEAYGTTGFQATNFGRAVQQVNAMIEKKLEPLAVDEDHHEDLTQSRRPLTGCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNDNYCKFEDWLMPILDQMVQEQNTEGVKWTPSKMISRLGKEINNPESVYYWAHKNHIPVLSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINMQAIFAKRTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRMDAQPVKVYADASLVFPLLVAETFAQKADAFRAEKNED
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.  This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine.  Hypusination is unique to mature eIF-5A factor and is essential for its function.
What are the official names of this protein?
Deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: Y2505_MYCUA
Sequence: MGMRPTARMPKLTRRSRVLILIALGVIALLLAGPRLIDAYVDWLWFGELGYLSVFTTVLVTRFLVFLVAGVLVGGIVFAGLALAYRTRPVFVPNNDNDPVARYRTVVLARLRLFGIGIPAAIGLLAGIVAQSYWVRIQLFLHGGDFGITDPQFGKDLGFYAFELPFYRLLLSYLFVAIFLAFVANVVSHYLFGGIRLTGRSGALSRSARIQLVSLVGVLVLLKTVAYWLNRYELLSHTRGGKPFTGAGYTDINAVLPAKLILMAIAVICAAAVFSAIVLRDLRIPAIGLVLLLLSSLIVGAAWPMIVEQISVKPNAAQKESEYISRSITATRQAYGLTSNVVTYRNYTGDGEATAQQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFPDQLSIDRYFDRNNNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGFIASPANTVRGIANDPNQNGGYPEFLVNVVGANGTVVSDGPAPLDQPRIYYGPVISNTPADYAIVGKTGADREYDYETSADTKNYTYTGSGGVSVGSWISRTVFAAKFAERNFLFSNVIGSNSKILFNRDPAQRVEAVAPWLTTDSAVYPAIVNKRMVWILDGYTTLDNYPYSQLTSLSSATADSNEVAFNRLLPDKQVSYIRNSVKATVDAYDGTVTLYQQDEQDPVLKAWMQVFPGTVKPKGDISPELAAHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQPPYYIVAKNIAKNDNSASYQLISAMNRFKRDYLAAYISASSDPATYGKITVLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVGQGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKIGYGPTVRDALNGLFGPGAGDAATGIQPTEGGAPANVPPNNAPSPEALPGTPPSPPTAVPPAPEASVTLSPARAAAMKEIQSAIGAARDAQKKGDFAAYGAALQRLDDAITKFNNTQ
What are the official names of this protein?
UPF0182 protein MUL_2505.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_LEIXX
Sequence: MQTAEIHRRWLDFFARRGHTVVPSASLVSDDPSLLFTVAGMVPFVPYLTGIVPAPFPRATSVQKCIRTLDIEEVGKTPRHGTFFQMCGNFSFGDYFKEQAIAFAWDLLTTAETEGGLGFDPKDLWVTVYEEDDEAREIWRRVSGLAEERIQGLGKDTNYWSTGQPGPAGPCSEIFFDRGPAYGIDGGPATDDDRYVEIWNLVFMQFLRGEGTGKDDFEILGDLPKKNIDTGLGLERVAFLKQGVENMYEIDQVRPVLDRAAELAGKPYGNEAHEDDVRLRVVADHVRSALMLMTDGVTPSNEGRGYVLRRLLRRTVRAMWLLGVEAATFPALFPVSRDAMKAAYPEVETEFARTSQLAYAEEETFLRTLVAGTSILDTAVANTQKAGKRELAGDTAFLLHDTYGFPIDLTLEMAEEAGLSVDRAAFDTLMADQRARAKADAKAKKTALADLSVYSGLRALGETVFTGYTELETESSVLGLIIDGHSANKAVEGQVAEVILGATALYAEAGGQDADTGTIVGPGYVLDVLDVQKPVRGLVSHRVLVRSGEVGVGVPATSLVDADYRRGAKQAHSGTHIIHAALRQVLGSNAHQSGSYNKAGYLRLDFSWNQALSPETRSEIEEISNSAIRQNLEVTTRELPLAEAKALGAMALFGEKYGDTVRVVDIGGPWSRELCAGTHVARSAEIGLINLVSESSVGSTNRRVESLVGLEAFKDLAVERTIVSQLSSSLKTPREQLPEKIADLMASLKAAEKRIQAFEARAVLDRVQGLLEAVSRRGAVQVVAADAGTLSTADDLRLLAITVRDRLGSDPATVALAALAGGKPVVIVATNQAARDAGVTAGALAKTAAGVLGGGGGGKADLAQGGGTDATAIPAALAAVSTAIG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEC3_MANSE
Sequence: WNPFKELERAGQRVRDAIISAGPAVATVGQAAAIARG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Bactericidin B-3, Cecropin-like peptide B-3.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLHC_PARAM
Sequence: MASKSVVLEAREITLAIELIELGARLQLLEAETSLSRDRLVKLYKELKGVSPPKGMLPFSTDWFMTWQPNFHSSLFYNIYRFMAGHGGCRAIESIVKSYRLYLEHVQLQDDEPVLSLTRAWTLVRFFDSGMLQLSVCRRCGGQFVAHAHDPQHAFVCGLCQPPSRAGKTKKAAQTRPERQSAVAGIPAEVPQVAEARAHEARCTAPTLDTFVTAEV
What is the function of this protein?
Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhC.
What is the protein family that this protein belongs to?
Belongs to the FlhC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_HAEI8
Sequence: MKNKKLLVMAGGTGGHVFPAIAVAQTLQKQEWDICWLGTKDRMEAQLVPKYGIPIRFIQISGLRGKGIKALLNAPFAIFRAVLQAKKIIQEEKPDAVLGMGGYVSGPAGVAAKLCGVPIILHEQNAIAGLTNKLLGKIATCVLQAFPTAFPHAEVVGNPVREDLFEMPNPDIRFSDREEKLRVLVVGGSQGARVLNHTLPKVVAQLADKLELRHQVGKGAVEEVSQLYGENLEQVKITEFIDNMAEAYAWADVVICRSGALTVCEIAAVGVAAIFVPFQHKDRQQYLNAKYLSDVDAAKIIEQADLTPEMLVNYLKNLTRENLLQMALKAKTMSMPNAAQRVAEVIKQYSN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y040_RICCN
Sequence: MLPDQALPIYNLLEKLLKETHKSINDCYKNENLYKHQLAKIYCQQAQICTPNGSTKLSKNSIGLYENAANLGSEEANIKLGKIEFKSGNYVKALEYFKNLCKRSF
What are the official names of this protein?
Uncharacterized protein RC0040.
Protein: YOHJ_ECO55
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAVSTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRD1_MYCLE
Sequence: MSVHTTDAKPDSEVDRLLDGLNPQQRQAVVHEGSPLLIVAGAGSGKTTVLARRIAYLIAARSVGVSQILAITFTNKAAAEMRERVARLVGDHTGPSMWVSTFHSTCVRILRNQASLIGGLNSNFSIYDVDDSRSLLQMIGQDMGLDIKRYSPRLMANAISNLKNELIDAESAVANLSSDTDDLARTVATVYGEYQRRLRTANALDFDDLIGETVGILQAFPQIAEHYRRRFRHVLVDEYQDTNHAQYVLVRELVGHGARNSPDDMPPGELCVVGDADQSIYAFRGSTISNIEDFERDYPDTTTILLEQNYRSTQNILSAANSVIARNFGRRDKRLWTDAGKGELIVGYVSDNEHDEAKFIADEIDALVGGGEITYDDVAVLYRANNLSRSLEEVFIPTGIPYKVVGGFCFYESKEIRDLIAYLRVLDNPGDAVSMRRILNTPRRGIGDRAEACVSVYAENTGTSFADALQAVAEGKVPMLNTRSVKAIAGFVALLDDLRCRVDDDLGELVESVLERSGYLRELESSTDPQELARLDNLNELVSFAHEFSTEQANAAALAKSLHTPEDEDVPDTGALAAFLEKVSLMSDTDQIPENNSGVVTLMTLHAAKGLEFPVVFVTGWEDGMLPHMRTLGDPTELSEERRLAYVGITRARQRLYLSRAITRSSWGQPILNPESRFLREIPPELIDWRRSILTDSYSTPASGASRFGRVRPSSIRSGASKRALLVLAPGDRVTHDKYGLGRVEEVSGVGESAISLIDFGSSGRIKLMHNHAPVTKL
What is the function of this protein?
DNA-dependent ATPase, acting on dsDNA with a 3'-ssDNA tail, unwinding with 3'-to 5'-polarity.  Also highly efficient on nicked DNA.  Involved in the post-incision events of nucleotide excision repair (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase UvrD1, DNA 3'-5' helicase UvrD1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: RL32_PHYAS
Sequence: MAVPFRRTGKTAKRKRRTHYKLDNPALVVCKQTNNFTLSHRVTKNSGYYKGRLLLENNKIVKKVA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: BETB_ECO7I
Sequence: MSRMAEQQLYIHGGCTSATSGRTFETINPANGNVLATVQAAGREDVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETSTVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRHEPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMMANFFSSGQVCTNGTRVFIPTKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHRDNVLRYIAKGKEEGARVLCGGDVLKGDSFDNGAWVAPTVFTDCSDDMTIVREEIFGPVMSILTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PPZG_METRR
Sequence: MNDFVFSDIPDNVKPMASVEFDDPLTIATGDVLNWTLWLTRNFPALSSIIMRLPSSLVSMVTSSFEGANQMVQVKTSTHNLYSLSLPTHARKQIISQLVEHEKNHIGPKSKDCVMQRLLNAHRDSESKISIPTPDATLRSEAVGFTLAGTADPPNILALGTFMAARDSEMQKGLYKELKAIWPDLRSPAPSYNLLHQLPLLRGIIKESIRFTHGVATGPARLVGAGGARIGGYNVPAKASSFSAAATSDCS
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of pyrrolopyrazines, secondary metabolites showing insecticidal activity (PubMed:30452111).  The single multifunctional NRPS ppzA is responsible for the biosynthesis of peramine (PubMed:30452111).  The condensation domain of ppzA is proposed to catalyze formation of a peptide bond between 1-pyrroline-5-carboxylate and arginine (By similarity).  The methylation domain of ppzA would catalyze the N-methylation of the alpha-amino group of arginine (By similarity).  The reductase domain is proposed to be responsible for reduction of the thioester and the cyclization to form an iminium ion resulting in release from the peptide synthetase (By similarity).  Deprotonation of this intermediate and oxidation of the pyrroline ring would give rise to peramine (By similarity).  This final oxidation to give the pyrrole functionality may be spontaneous (By similarity).  In Epichloe species that produce only peramine, the peramine synthetase gene is not localized in a gene cluster, in contrast to Metarhizium rileyi that contains additionnal pyrrolopyrazine biosynthesis genes (Probable).  The 2-oxoglutarate-Fe(II) type oxidoreductases ppzC and ppzD could be candidates for conversion of proline into an oxidized derivative to be used by the ppzA A1-domain as substrate (Probable).  The other ppz genes encode proteins predicted to derivatize peramine into more complex pyrrolopyrazine metabolites (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase ppzG, Pyrrolopyrazine biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RL21_CLONN
Sequence: MYAVVQTGGKQYRVQEGDVLFVEKLNAEVDSNVELTEVLAVNKDGKLVVGAPVVEGAKVVAKVLKQGKAKKVVVFKYKPKKDSRKKNGHRQPYTKLQIERIEA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: HSLV_VIBPA
Sequence: MTTIVSVRRNNKVVIAGDGQVSLGNTVMKGNARKVRRLYNNKVLAGFAGGTADAFTLFERFESKLQMHQGHLTKAAVELAKDWRSDRALRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGAYAQAAATALLENTDLDAREIAEKALNIAGDICVFTNHHHTVEELDSTTEPETPAA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIEAP_MACFA
Sequence: MAENLKRLVSNEALRTLQEKLDSWLKEYNTNTCDQNLNHCLELIEQVAKVQGQLFGILTTAAQEGGHNDGVETIKSRLLPWLEASFTAASMGKPVDSKVPSLQNTFDRERRKDPSPRDRDMQQLDSNLNSTRSQLNQVQDDLAETEKNLEETKNRSAISLLAAEEEINQLKKQLKTLQAQEDARHRHTDQRSSENRRSEPRSSEERRCEQWSSLKRNADQRDTEVTSDYKKQLRNLKEEIAVLSAEKSALQGRSSRSRSPSPAPRSRSCSRSRSASPSTAVKVRSPSPNRSKLSNVARKAALLSRFSDSYSQARLDAQCLLRRCIDKAETVQRIIYIATVEAFHVAKMAFRHFKIRVRKSLTPSYVGSNDFENAVSDYVICHLDLYDSQSSVNDVIRAMNVNPKISFPPVVDFCLLSDFIQEICCIAFAMQALEPPLDIAYGADGEVFNDCKYRRSYDSDFTAPLVLYHVWPALMENDCVIMKGEAVTRRGAFWNSVRSLSRCRSRSLSPICPRSQIGLSTMSRSRSPSPIRCGLPRF
What is the function of this protein?
Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage.  Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen.  Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade unhealthy mitochondria by accumulating lysosomes (By similarity).  The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity).
What are the official names of this protein?
Mitochondria-eating protein, Spermatogenesis-associated protein 18.
What is the protein family that this protein belongs to?
Belongs to the MIEAP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane. Note=Localizes to the cytoplasm under normal conditions. Relocalizes to mitochondrion outer membrane following cellular stress. Colocalizes with BNIP3 and BNIP3L at the mitochondrion outer membrane.
Protein: AMPL_MESAU
Sequence: GVLFASGQNLARTLIEFLLR
What is the function of this protein?
Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides.  The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme.  For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates.  Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
What are the official names of this protein?
Cytosol aminopeptidase, Cysteinylglycine-S-conjugate dipeptidase, Leucine aminopeptidase 3, LAP-3, Leucyl aminopeptidase, Peptidase S, Proline aminopeptidase, Prolyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBP24_PETHY
Sequence: MIIMGRGKIEVKRIENKTSRQVTFSKRRAGLLKKTHELSVLCDAQIGLIIFSSKGKLFEYCSQPHSMSQIISRYLQTTGASLPVEDNRVQLYDEVAKMRRDTLNLQLSLQRYKGDDLSLAQYEELNELEKQLEHALNKIRARKLELMQQQMENLKKTEKMLEKENHDMYQWLMNNQMYKQESAAMDHEDHHHHHEHQQAITELNLLGEQPLLSHFTFFGDQEQPSTSTVNHFASISLTSPPANSISPYRLQPSHPNLQDSHVHGPSYD
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
MADS-box protein FBP24, Floral-binding protein 24.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHSC_RICCN
Sequence: MTKTKQEIYNKRPTSPHLTIYKPQISSTLSILYRMTGVALFFAVSILVWWLILSKYDNNYLQLAECCIIKICLVAVSYAWFYHLCNGIRHLFWDIGYGFSIKLVNITGWCVVVGSVLLTVLLWV
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase cytochrome b556 subunit, Cytochrome b-556.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b560 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.