PharMolix/UniProtQA huggingface dataset:
Protein: PROB_PSEPF
Sequence: MRSKVTGAQRWVVKIGSALLTADGKGLDRTAMGVWVEQMVALHEAGVELVLVSSGAVAAGMSRLGWTARPSAMHELQAAAAIGQMGLVQAWESSFAEHGRHTAQILLTHDDLSDRKRYLNARSTLRALVELKVIPVINENDTVVTDEIRFGDNDTLAALVANLVEADLLVILTDRDGMFDADPRSNPDAQLIYEARADDPTLDAVAGGTGGALGRGGMQTKLRAARLAARSGAHTIIVGGRLERVLDRLKAGERIGTLLSPERGMLAARKQWLAGHLQTRGTLVLDDGAVSALSQGNKSLLPVGVKLVQGSFRRGEMVVCVAPDGREIARGLANYSALEAQKIIGQSSDAIVGLLGYMAEPELVHRDNLILV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM2_HCMVA
Sequence: MSWAKQRVPFLDDDDGEEENDVQDDVDSPVPTRPLVIDEDAEPAAGTSGGLEGGGGDDEDGEDGHALPDLDDDLLLQFEPMLPRVYDLLLPSLDARLNFVNAGQKYAAFLKYVHGDCATCSHGEILREKTQLLTAIVSKLMDINGILEGKDESAPGK
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.
What are the official names of this protein?
Tripartite terminase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM2 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: SYT_CAMJ8
Sequence: MEKEVIAYLDNETIIDSQSVKNTNLKEIYFDNSKESLEVIRHSCAHLMAQAIKNLYPEAKFFVGPVIEDGFYYDFRVESKIGEEDLVKIEKKMKELAEAKIEISKYEITKNEALAKFQNDDLKQEVLLRIPDGAVSIYKQGEFEDLCRGPHVPNTKFLRFFKLTRVAGAYLGGDEKREMLTRIYGTAFADKESLKEYLTIIEEAKKRDHRKLGTELKLFTFDDEIGGGLPIWLSNGARLRSKLEHILYKIHRLRGYEPVRGPELLKADAWKISGHYANYKENMYFTQIDEQEYGIKPMNCVGHIKIYQSDVRSYRDLPLKFFEYGVVHRHEKSGVLHGLFRVREFTQDDAHIFCMPSQIKEQVLEILAFVDNLMKLFDFSYEMEISTKPEKAIGDDEIWEVATKALKEALDEQGLKYGIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDFNLPSRFKLEYTDSDNEKKQPVMLHRAILGSFERFIGILTEHCAGEFPFFIAPTAVGIVPIGEAHIAYAKEIQKELLELNIDSEVYEKNESLSKKIRTAEKQKLPMILVLGDDEVAKRSVALRDRRAKEQKNLSLDEFIKLVKEKMSEVHF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GERN_BACCE
Sequence: MEFEFFFQIALILLSTKLAGDLSVRLGQPSVLGKLIVGIVIGPAVLGWIENSELLTQLSNVGVILLMFMAGLETDLEELNANRNSSLAVALGGIILPFVGGYVSGLVMGMEQGNAVFLGLLLCATSVSISVQTLRDLGKMKTRESTTMLGAAVFDDILVVILLAFAMSFLGTDDVNLTMVILKKVVFFASIILIGWKGVPAIMRWLSPLRVSESIVSAALIICFSFAYFGELLGIAGIIGAFAAGIAISQTNYKHEVEKKVEPIAYAMFVPVFFVSIGMNITFDGIGNQIWFILALTVIAVLTKLIGCGFGARMTGFDAKSSAIIGAGMVSRGEVALIIAGTGLSSGLLAQDYFTAIVIVVILTTMITPPMLKYTFGAKDKAMKASK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.  Can also use potassium as a coupling ion, without completely replacing H(+).  This Na(+)/H(+)-K(+) antiport is much more rapid than Na(+)/H(+) antiport.  Can also extrude lithium.  Important for the inosine-dependent germination of spores.
What are the official names of this protein?
Na(+)/H(+)-K(+) antiporter GerN.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: IF2_ANADE
Sequence: MSKKRVHELGKQLKEQGIELSNQELVEKLHALGYLEVKSHSSSLEDDQAHAAYEKILAERKPKPAPARPSGPGFVVRKRAHVEPPTVTAPAAPPSPEPEYAEPQYAEPQAEQAYEPEPQAAQPEAGAEPAAAPEPPAEAAPLAAQAAPSPGAEAAAPAAPQAQPAQPAAPAAPPAPTAQPSAPPPAAAQPRPPQPSAPSRPPPPGYRPAPPPGARPPVSAAPGAPGQPGAAGQPPRPPVDPRTLRPTSTQAVVISRPLVPVRRVTPPTSARQQFPVAPGPRALGEVRELKVVPGSLGREREFIDVSRDKRRGRQPGRPISEEQAKSLSGKELLQAAISDRAYIPIRGKKKKPTKKGAKTQITEKAEHKKVIRIEESISVSELSQVMGVKASDLIRKLMQMGKMVTINAQIDADTAATLALEHGYTVEKKGFEVEEFIPEVEVDESKLVIRPPVVTVMGHVDHGKTSLLDAIRQADVAAGEAGGITQHIGAYSVNTPQGPITFLDTPGHEAFTAMRQRGAQVTDLVVLVVAADDGVMPQTVESIKAAKAAGVTILVAINKVDKPQAAPERVMQQLTEYELVAEQWGGTTIMLPVSARTKQGIPELLEYIALQSEVLELKANPDKLAAGRVIEAKLEKGRGPVATVLVEEGTLRVGDALVTGVHFGRVRAMMNERGEQVDNVGPGYPVEVLGLSGVPVAGDEFDVVEDEKAAKEVAQHRATKQRQKELGGVKKATLEDLFAKAKTSAQKVLNLVVKADVQGSSEAVSQALEKAATKKVGVKILESAVGAITKSDVLTAAAGNAVIVGFNTKPETEIENIASQQGVKILMFGIIYEAVDRIREEMAGLLEPIIKEKPLGKAEVRQVFNIPRVGQIAGSAVTEGVVKRAGHVRVVRDRKVVFTGKIGSLKRVKDDVREVAQGFECGIGVDGFSDVKQGDVLEVYELEEIRQSLD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_BACCQ
Sequence: MKKYILSLDQGTTSSRAILFNKKGEIVHSAQKEFTQHFPKPGWVEHNAQEIWGSILAVIATCLSEADVKPEQIAGIGITNQRETAVVWDKTTGKPIYNAIVWQSRQTAEICDELKEKGYSEMVREKTGLLIDAYFSGTKVKWILDNVEGAREKAENGDLLFGTIDTWLVWKLSGGKAHVTDYSNASRTLMFNIHDLQWDDELLDMLTVPKSMLPEVRPSSEVYGETIDYHFFGQNVPIAGVAGDQQAALFGQACFGEGMAKNTYGTGCFMLMNTGEKAVASEHGLLTTIAWGIDGKVNYALEGSIFVAGSAIQWLRDGMRMFKDASESEVYASRVESTDGVYVVPAFVGLGTPYWDSEVRGAMFGVTRGTTKEHFIRATLESLAYQTKDVLCAMEADSGIELKTLRVDGGAVKNNFLMKFQSDILDVPVERPVINETTALGAAYLAGLAVGYWKNQDEIKEQWHMDKRFEPTMEAEISEELYAGWKKAIEATKAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: ACYP_CUPNH
Sequence: MKKETWRLVAHGRVQGVGYRAACADAADDLELGGWVRNRLDGTVEVMAHGTVRQLEALQAWMEQGPPAAQVTLVEVGPGEGEFAGFEFRPTI
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RUVA_ECO8A
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RIMP_TOLAT
Sequence: MATLEQRLTELLDAPIVALGYELWGIEFIRAGKHSTLRVYIDHANGISVDDCAEASHQVSALLDVEDPITTEYYLEVSSPGMDRPLLKPEHFARYIGQVATVTLRMAVNNRRKYKGTIKQVDGEMITLTIDGRDEILAFANIQQANLIPNFD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLM2_GIBZE
Sequence: MLLIIVVLVGTLIYFLSFHNKKRHGLPPGPKPLPIIGNIKDMPPKGVAAFRHWLKHKDTYGPVSSVSVLGQPLILIHDREAAHYLFDKSSGKSSGRPSANFGGRLCGFDQILSLQQYGDTFKRHRKLVHRQMGTRAGAAKFRQIQDVESHRFLLRSLDNPGNLMEHIRKEAGGVILKATYGYSIEPHKPDPLVHLVEFMVEGISIVVVPMKFVVDFLPWLEYIPECLPGMSFKARARRWRTILNNTIEAPYQFVRQQMAKGIQFESYVSSLLTQEKLKGGNDTLDETYEADIKRTAAIMYAGGADTTVSTIQSFVLAMMVYPEVLKKAQAEIDNVIGPDRLPGFEDRENLPYINSMVKESLRWMPAVPMGAAHKADDDIYYGDLCIPKGSFLLPNVWWFLHNPETYQDPERYDPDRYLEPRNEPDPDSNCWGYGRRICPGRLLADESIFIVIARVVAAFDIEKDVDEQGNTIEPKVEFTTEGALSRPVDYPYRIKPRNAKCVDLIRAVEKEHPWDKGDASLLQQDMVVL
What is the function of this protein?
Cytochrome P450 monooxygenase involved in the biosynthesis of culmorin, a tricyclic sesquiterpene diol reported to have antifungal activity and some phytotoxicity to wheat coleoptile tissue, contributing to Fusarium head blight disease (PubMed:19880637).  The terpene cyclase CLM1 is responsible for the cyclization of farnesyl diphosphate into the intermediate longiborneol (PubMed:19880637).  Longiborneol is then hydroxylated in a regio- and endo-stereoselective manner at position C-11 by the cytochrome P450 monooxygenase CLM2 to produce culmorin (PubMed:26673640).  Additional non-specific oxygenases are also able to hydroxylate longiborneol at other sites than C-11 leading to 3-hydroxylongiborneol, 5-hydroxylongiborneol, 12-hydroxylongiborneol and 15-hydroxylongiborneol (PubMed:26673640).  Moreover, another oxygenase capable of installing a C-11 exo-hydroxy group in longiborneol can also yield 11-epi-acetylculmorin (PubMed:26673640).  The production of these longiborneol derivatives is dwarfed by the high abundance of culmorin, suggesting that CLM2 displays superior enzymatic activity to the unidentified, possibly promiscuous, additional oxygenases (PubMed:26673640).
What are the official names of this protein?
Cytochrome P450 monooxygenase CLM2, Culmorin biosynthesis protein 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DNLJ_FLAPJ
Sequence: MTVLQKIQSLREELNLHNYNYYVLDNPTISDYDFDVKLTDLQSLEKNNPEYFDENSPTQRVGGTITKNFETLKHDYRMYSLDNSYSKEDLLDWENRIQKALGDVPLEYICELKYDGASISITYENGRLVRAVTRGDGFQGDDVTNNIKTIKAVPIKLKGDFPEKFDIRGEIILPFAGFEKMNQDLIEIGETPYSNPRNTASGSLKLQDSAEVAKRPLDCLLYSLIGNNLPFQSHFEGLEKARLWGFKVPKQSHLAKNMNEVFDFINIWDKNRHTLPYETDGVVIKVNDLHLQDELGYTAKSPRWAIAYKFKSEQVFTQLNSISYQVGRTGSITPVANLEPVQLAGTIVKRASLHNADQIEKLDIRINDTVFVEKGGEIIPKIIGVDLQKRPSNSQKTAYITHCPECQTKLERKEGEANHYCPNFYGCRPQIIGRIQHYISRKAMDIEGLGGETVALLYDNGLVKNYADLYDLSVEQILPLERMAQKSAENLVQGVQNSKNIPFENVLFALGIRYVGETVAKKLAKHYKNIDAIANANLLELVMVDEIGDKIAQSVVEFFDNQENISVLERLKNNGIQLAISEENNTVVSNKLLGKIFVVSGVFEIYSRDELKKAIEDNGGKVGSSISAKTNYVIAGQNMGPAKLEKANQLKVSIISESDFSALLTS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: BTUC_VIBVY
Sequence: MELHQLIAHKEKRWRATLLVMLAVLLVLSALYLMVGEVFLSPFSSLSSFEHKLLVDLRLPRLMAAMVIGAALAVSGATLQVLLGNVLAEPGVLGISGGASLAMVIALFLLPVMPTPTVFMLAAIIGALVFTLILVGMARAMHLSTSRMLLVGVALGILSGAFVTWAFYFSDDLSLRQLMYWLMGSIGGASWHHHMVTLVLLPVLVWLCLQGQTLDKLMLGETHAVQLGVDVHKVRWRLILAVSILIGCAVALGGIISFVGLVVPHLLRMAFGSENRFLLPLSAFAGATLLVFSDIWARTLLDSAELPLGVMTTTIGAPIFIWMLIRSHDAH
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2600_PSET1
Sequence: MQSLENHFLIAMPSMQDPFFKRAVTYICEHNEDGAMGLVINQPINITVGELLDKIEIDNDKTQQAAQVSVYAGGPVKTDRGFVLHSPKHGYSASQALSSDIMITTSKDVLASLTTAQAPEQFIITLGYSGWEQGQLEQELLDNSWLIIKADPKIIFDTPVEKRWEKAVSMLGFDISQLSPEAGHA
What are the official names of this protein?
UPF0301 protein PSHAa2600.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RIMM_PHOPR
Sequence: MSSQNQDLVVVGKLGATYGIKGWLKVFSYTEQSESIFAYQPWLIKVKGEWKPIQIESWKKHGQGMVAKLEGLDIREDAQIFTNAEVAVHADQLPALSGEEFYWRELYGMSVVTTEGYDLGKVTDILETGSNDVLVVKANLKDAFGQKERLIPFLDEQVIKSIDRTAQRIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_BRASO
Sequence: MRPSRRAPDEMRAVSLERGVVKYAEGSCLVKFGDTHVLVTATLEDRLPPWLKGQGRGWITAEYGMLPRATLERTRREASAGKQTGRTVEIQRLIGRSLRTAIDLEALGERQITVDCDVLQADGGTRTASITGAWVALADCIRWMKARNMIKTEVLRTNVAAVSCGIYNGTPVLDLDYAEDSEAETDANFVMTGDGRIIEVQGTAEKTPFSEAEFLALMALARKGVGRLVDLQKMAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SECA_SHESM
Sequence: MFGKLLTKVFGSRNDRTLKGLQKVVNKINALEADYEKLTDEQLKAKTAEFRERLAAGASLESIMAEAFATVREASKRVFEMRHFDVQLLGGMVLDSNRIAEMRTGEGKTLTATLPAYLNALTGKGVHVITVNDYLARRDAENNRPLFEFLGLTVGINVAGLGQQAKKDAYNADITYGTNNEFGFDYLRDNMAFSPQERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYIKINTLIPNLIRQDKEDSEEYVGEGDYSIDEKAKQVHFTERGQEKVENLLIERGMLAEGDSLYSAANISLLHHVNAALRAHTLFERDVDYIVQDGEVIIVDEHTGRTMPGRRWSEGLHQAVEAKEGVRIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVRKDMADLVYLTANEKYQAIIKDIKDCRERGQPVLVGTVSIEQSELLARLMVKEKIPHQVLNAKFHEKEAEIVAQAGRTGAVTIATNMAGRGTDIVLGGNWNMEIEALENPTAEQKAKIKADWQERHDAVVAAGGLHILGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDSLMRIFASDRVSGMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVYAQRNELMDAESIEDTIKNIQDDVISAVIDQYIPPQSVEELWDVPGLEQRLQQEFMLKLPIQEWLDKEDDLHEETLRERIITSWSDAYKAKEEMVGAPVLRQFEKAVMLQTLDGLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQLLSTLKHDVISVLSKVQVQAQSDVEEMEARRREEDAKIQRDYQHAAAEALVGGDDGSDEMMAHTPMIRDGDKVGRNDPCPCGSGRKYKQCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SHU3_ECOLX
Sequence: MKKYDRGWASLETGAALLIVMLLIAWGAGIWQDYIQTKGWQTEARLVSNWTSAARSYIGKNYTTLQGSSTTTTPAVITTTMLKNTGFLSSGFTETNSEGQRLQAYVVRNAQNPELLQAMVVSSGGTPYPVKALIQMAKDITTGLGGYIQDGKTATGALRSWSVALSNYGAKSGNGHIAVLLSTDELSGAAEDTDRLYRFQVNGRPDLNKMHTAIDMGSNNLNNVGAVNAQTGNFSGNVNGVNGTFSGQVKGNSGNFDVNVTAGGDIRSNNGWLITRNSKGWLNETHGGGFYMSDGSWVRSVNNKGIYTGGQVKGGTVRADGRLYTGEYLQLERTAVAGASCSPNGLVGRDNTGAILSCQSGTWKSSSASIWTNIKTFTLYPKNTQVLGRFKLCINTYRIDGREMAETEVVPIDMPDSNGEMIWQAKNYTQYSSYFMKITCLK
What are the official names of this protein?
Shufflon protein B.
Protein: YBEY_BACP2
Sequence: MTLLIDLIDETGQVSKEQLEEVEKLLQFAADALEVKDQAEVSVTIVSNEEIHQINKEYRGKDAPTDVISFALEEEGEGEIEIIGADDIPPVLGDIIISVDRTKEQAEEYGHSFMRELGFLTIHGFLHLLGFDHMTEEDEKEMFAKQTKILDDYGLSRSS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A37_VAR67
Sequence: MDEMVLLTNILSVEVVNNNEMYHLIPHRLSMIILCISSIGRCVISIDNDVNNKNILTFPIDHAVIISH
What are the official names of this protein?
Protein A37 homolog.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae A37 protein family.
Protein: TM174_PONAB
Sequence: MEQGSGRLEDFPVNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTVMGWIKYQGVSHFEWTQLLGPVLLSVGVTFILIAVCKFKMLSCQLCKESEERVLDSEQTPGGPSFVFTGINQPITFHGATVVQYIPPPYGSPEPVGINTSYLQSVVSPCSLITSGGAAAAMSSPSQYYTIYPQDNSAFVVDEGCPSFADGGNHRPNPDADQLEETQLEEEACACFSPPPYEEIYSLPR
What is the function of this protein?
Regulator of plasma phosphate homeostasis.  Decreases serum inorganic phosphate (Pi) uptake by regulating the sodium-phosphate cotransporter SLC34A1 trafficking by PTH and FGF23 in the kidney.
What are the official names of this protein?
Transmembrane protein 174.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YCHJ_SHIF8
Sequence: MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQDADYLIKTWHPSCGAAALRAELMTGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTEGGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ
What are the official names of this protein?
UPF0225 protein YchJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: DBX2_BOVIN
Sequence: MLPSAVAAHAGAYWDVVASSSLLNFPAAPGFGNLGKSFLIENLLRAGGAPPLGLPPPQHHGSAAALGAGAQVRSLPASPVPLKLCPAAEPVSPGGAPYGTRWAFQVLSPSADGARLPGRAPGDPDCAFQPPAPAPSKPFFLSAPPFYSACCGGSCRRPASPTAFAREESVLPLLTQESTSKVRRGILRRAVFSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKESQVKIWFQNRRMKWRNSKEKEVLSNRCLQEVVLQEDPLSRSALGFPSPCASLWEVSQQHPSPGWRENSPEPSERLIQGSPGAEALPPEAKSLQGALYLCSEEDARDKNALTGTV
What are the official names of this protein?
Homeobox protein DBX2, Developing brain homeobox protein 2.
What is the protein family that this protein belongs to?
Belongs to the H2.0 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS15_MICAN
Sequence: MALTQTKKQELISQYQAHETDTGSSELQVAFLTERINQLTEHLKANPKDHASRRGLLQMIGRRRGLLTYIQKKDQQRYQTLIGRLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SECA_CLOAB
Sequence: MGLLEKIFGTYSDREVKRIIPLVDKIDALDGSMQALSEDELKAKTAEFKQRYENGETLDDLLVEAFAVVREASSRILGLKHFREQIIGGIVLHQGRISEMKTGEGKTLVATLPSYLNAITGKGVHVVTVNDYLAKRDMEWMGQLYQYLGLTTGVIVHDLDQKQRQEAYAADITYGTNNEFGFDYLRDNMVIYKEERVQRPLHFCIVDEVDSILIDEARTPLIISGEGEKSTEFYKVADNFAKMLRKEKDFTIDEKTNSAILTDEGVEKAEKYYHIDNYADPQNMEIQHHTSQALKANYLMKRDKDYMVKEDEVVIVDEFTGRLMEGRRYSDGLHQAIEAKEGVKVQKESKTLATITFQNYFRMYEKLSGMTGTALTEEVEFREIYGLDVVVIPTHRPIARIDAPDIVYKTELGKFKAVVEDIVETNKNGQPVLVGTVSIEKSELLSSLLKKRGVRHQVLNAKYHEQEAEIISHAGEKGMVTIATNMAGRGTDIKLGEGVTDVGGLKIIGTERHESRRIDNQLRGRAGRQGDKGYSRFYVSLEDDLMRIFGSDKLKNMVEKLGLGDDDAIESKMVSSAIENAQKKVEGNNFDIRKTLIQYDDVMNKQREIIYKQRSEVLEGENLKDQIEGMIKDLIYNAVNSHISGVDEELESDIEAILNYLDDICLPRGIVEVEELATMSNDEIKEKLYSLAKEIYERKEEEFSSDQMRELERVILLRVVDTKWMDHIDSMEHLKQGIGLRAYKQQDPTQAYQMEGSDMFEEMVENIKVETVRYLFHVQAERAPERQRVVKETEINYSGPDAGDTKKEPVRRKEKKIGRNDLCPCGSGKKYKDCCGRRA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: LSY2_CAEEL
Sequence: MLTRRNAKQSQRNSADQSLSEFNSSSMTHGSNQSVYHHNQHMDDSEMMMDEQDYSQYQMGFPEEDEMVEGMMTPRAVHQCNVCNKIFVSYKGLQQHAVIHTDQKPFRCDICSKSFRFKSNLFEHRSVHTGFTPHACPYCGKTCRLKGNLKKHLRTHVTTKEELEAAWRPFASNRRPPADIPDDAIVLRGAGGPYYTPPPRPKKKKLGLGEPEHWVDKLRRGDLLPQVELEDKIRRLEDTIFNNMSLERWGNLFEIAKSIAFETHDCPVCKSQFMTRMDCVSHHTLEHENHREGLEFFCEKCYRPFADEASYNQHMSYHTRVSSLIETGEIVPQPADPEILVPTNDEFQMLFGANFGQQMMEPQLI
What is the function of this protein?
Involved in transcriptional regulation (By similarity).  Required to specify left-right asymmetry of the ASE gustatory neurons, probably acting upstream of microRNA lsy-6 (PubMed:16291785, PubMed:26050091).  Involved in maintaining the distinction between somatic and germ cells, perhaps acting by repressing germ cell-specific genes in somatic cells (PubMed:26050091).
What are the official names of this protein?
Zinc finger protein lsy-2, Laterally symmetric 2.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Localization in nuclear speckles/punctae is dynamic, appearing to move.
Protein: MMM1_CRYNB
Sequence: MSETFSPNLTFTEGFVLGQASFLIILLLFIRYVVFSPSEQIDHEGWRKRRAERADLLSNHTPPPLSNLLSKTSYDMSIHPAESSDWVNVLLAQILQGYRNDLLSEGGEEGARQRIEGWLNPKGENLSWLDPIDVTSLSLGTSYPLLSNARIRPADGQGRLRAEIDVDYLDSLSMTLSTAVLVNFPKPRFAVLPVTLGVELVSIGGTMSVQLHEPIEDRQHIHVNLLPDFHLNLKVTSLLGSRAKLQDIPKLEQLIVSRLRNLVQDRFVHPNHISLALPRILSPSVSSTPILEGLGEGAVDAMKDAVSDGMKRMVEDFMGENPVEGALNGQGEEQWLDDDFPPTPLVQPPGTFPTLSVSSRQSHRQSLPPSRPQSTTQGQPQLFYRRPLIHPTQSYPHYNTYTLDPQIPHSVSYRHPPRGSHVHNPPETPVPQRPSHGQGRMSTTSSLTPSQSQSQFRFRGQFASGVTPGQVGTSR
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.