PharMolix/UniProtQA huggingface dataset:
Protein: AROC_CHLL2
Sequence: MIRYLTSGESHGPALTAIVDGLPAGIDITQNDIDSQLLRRQQGYGRGGRMTIESDKAEVMSGIRFGKSIGSPITLLIRNRDWENWTTTMARFEEPVEEIAKISIPRPGHADLAGRIKYGFNDIRPVIERSSARETAARVAAGSLSRVFLKALGIEIGSYVSAIGSAAEPTVNPAVEELLVNGAECLALEADRSSVRMLNKSAEAGAIAAIDEVKKQGDTLGGIIEIFITGVPMGLGSYVQHDRRLDAMLVSALMSIQAIKGAEIGHAFENSRKPGSQVHDEFFLSENTGLERKTNRAGGLEGSMSSGQTIHLRAAMKPISSLVTPLHSFDLETMKPTLSRFERSDTCAVPAAGVVAEAVVAPVIANALLEKLGGDHFIEIKSRLETYRDHLHRTFKA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL33_RHOCS
Sequence: MAKQNTVLIKLVSSADTGFFYVKKKNPRKTTEKLEFKKYDPVARKHVVFKEAKMK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS18_CORU7
Sequence: MKRNNMKRARMEQSRRPKKNPLKAEGIEQVDYKNYALLRKFISDRGKIRSRRVTGLTPQQQREVATAIKNAREMALLPFNSR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RL10_XANOP
Sequence: MALNLSQKQEVVAELADVAAKAHSLIAAEYAGTTVSQMTAMRKQARETGVFLKVVKNTLAARAVEGTDFAVAADKLVGPLLYAFSMEEPGAAGRLIKEFAKSNDKLQAKVVSIGGELFPAGHVDVLASLPTRDQALAMLARVLSEPAAMFARAVKAVGDKQGGGDAAAAAVAETAEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: IFIT3_MOUSE
Sequence: MSEVNRESLEAILPQLKCHFTWNLFREGSMSSHMEDRVCNQVEHLNSEEKATMYDLLAYIKHLDGESKAALECLGQAEDLRKSEHNDQSEIRRLVTWGNYAWIYYHMGRLSEAQAYVDKVRQVCQKFANPYSMECPELECEEGWTRLKCGRNERAKMCFEKALEEKPKDPECSSGMAIAMFRLEEKPEKQFSVDALKQAMELNPQNQYLKVLLALKLLRMGEEAEGERLIKDALGKAPNQTDVLQKAAQFYKKKGNLDRAIELLGKALRSTVNNSPLYSLVMCRYREILEQLQNKGDADSSERRQRMAELRRLTMEFMQKTLQRRRSPLNSYSDLIDFPEVERCYQMVISKESPDVEEEDLYERYCNLQEYHRKSEDLAALECLLQFPRNERSIEKEEVKEQT
What is the function of this protein?
IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication.  Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription.  Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27.  Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation.  IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels.  Up-regulates CDKN1A/p21 by down-regulating MYC, a repressor of CDKN1A/p21.  Can negatively regulate the apoptotic effects of IFIT2 (By similarity).
What are the official names of this protein?
Interferon-induced protein with tetratricopeptide repeats 3, IFIT-3, Glucocorticoid-attenuated response gene 49 protein, GARG-49, P49, IRG2.
What is the protein family that this protein belongs to?
Belongs to the IFIT family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: CRIPT_DANRE
Sequence: MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKMLTSKKARFDPYGKSGFATCRICKSSVHQSGSHYCQGCAYKKGICAMCGKKVIDTKNYKQTSV
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
Cysteine-rich PDZ-binding protein, Cysteine-rich interactor of PDZ three, Cysteine-rich interactor of PDZ3.
What is the protein family that this protein belongs to?
Belongs to the CRIPT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_RHOCS
Sequence: MATEGTGVSGLAARYATALFELADENKALDQTAQDLALLKQLMAESADLRRVVRSPLLSRSDQARAMDAVLAQVDVSGLVRQFVGLVARNRRLFALSGMIDGFLAELARRRGEQTARVVAARPLSQEQLDALTDALRRALGSKVSVDLRVDPSLIGGMVVKVGSRMIDSSVRTKLTKLKLAMKGVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL27_FRATH
Sequence: MAHKKAGGSTRNGRDSNPKYLGVKRYGGELVKAGTIIIRQRGTKTHPGVNVGCGKDHTLFALKDGTVKFHTGGALNRKFVSIEE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: MTNA_SYNS9
Sequence: MTLPRSLRWTGDHLDLLDQRCLPHTVVYRQLTHWREVSEAIRSMAVRGAPAIGVAAAWGVVLAAKAGDDLDQAIEGLRASRPTAVNLSWALNRMQTSAKSNGWVDVHQLERLASAIEAEDRALTQALVNHGVGVLPEDCRVLHHCHTGAVATAGVGTALGVIVAGHQRGIVKHAWLDETRPRLQGAALSAWELGCCGVPATVIVDGASGLLMRRGQVDVVLVGCDRVAGNGDVANKIGTYNLALAARAHGVPFYVCAPSSSIDITTVDGDAITIEERPEDEITHFRGELVCASGVRAWNPAFDITPAHLITGLITEFGVIRSPSRESIASLPFAN
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: DER_THEMA
Sequence: MATVLIVGRPNVGKSTLFNKLVKKKKAIVEDEEGVTRDPVQDTVEWYGKTFKLVDTCGVFDNPQDIISQKMKEVTLNMIREADLVLFVVDGKRGITKEDESLADFLRKSTVDTILVANKAENLREFEREVKPELYSLGFGEPIPVSAEHNINLDTLLETIIKKLEEKGLDLESKPEITDAIKVAIVGRPNVGKSTLFNAILNKERALVSPIPGTTRDPVDDEVFIDGRKYVFVDTAGLRRKSRVEPRTVEKYSNYRVVDSIEKADVVVIVLDATQGITRQDQRIAGLVERRGRASVVVFNKWDLVEHREKRYDEFTKLFREKLYFIDYSPLIFTSADKGWNIDRVIDAINLAYASYTTKVPSSAINSALQKVLAFTNLPRGLKIFFGLQVDIKPPTFLFFVNSIEKVKNPQKIFLRKLIRDYVFPFEGSPIFLKFKRSR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity).  Has GTPase activity but no ATPase activity.  GTP, GDP, and dGTP but not GMP, ATP, CTP, and UTP compete for GTP binding.
What are the official names of this protein?
GTPase Der, TmDer, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: GLGC_BRADU
Sequence: MSAVGNEPLARQALAFVLAGGRGSRLLELTDRRAKPAVYFGGKSRIIDFALSNAVNSGIRRIAVATQYKAHSLIRHLQMGWNFFRPERNESFDILPASQRVSENMWYVGTADAIYQNIDIIESHNARFIVVLAGDHIYKMDYEVMLRQHVDSGADVTVGCLEMPRAESSGFGIMHIDENGWIQEFLEKPADPPPMPGKPDVSLASMGIYVFDAKFLFDQLKRDAEDPSSNHDFGKDIIPYIVKNGRAIAHQFSTSCVRSGDDPRAYWRDVGTVDAYWAANIDLTDVVPELDLFDRAWPIWSYSEITPPAKFVHDEESRRGQAVSSLVSGGCIISGASLRRSLLFTGVRINSYANVENAVIMPYVNVGRGARLKNVVIDRGVEIPEGLVIGEDPELDAKRFRTTEQGISLITQPMIDRLNT
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: NUOCD_ECO5E
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPARVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UBIE_SALHS
Sequence: MVEDSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRMVGETGKVILADINDSMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTEKEKALRSMFRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHILPRIGSMVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: ARP7_YEAST
Sequence: MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN
What is the function of this protein?
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA.  The reaction requires ATP and involves an activated RSC-nucleosome intermediate.  Remodeling reaction also involves DNA translocation, DNA twist and conformational change.  As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.  This subunit is involved in transcriptional regulation.  Heterodimer of ARP7 and ARP9 functions with HMG box proteins to facilitate proper chromatin architecture.  Heterodimer formation is necessary for assembly into RSC complex.  Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
Actin-related protein 7, Actin-like protein ARP7, Chromatin structure-remodeling complex protein ARP7, SWI/SNF complex component ARP7.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
Protein: RS2_CLOPE
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMAPYIFTERNGIYIIDLQKTVKKAEEAYNFIREVSEAGKDVIFVGTKKQAQEAVKEEAERSNMYFVNHRWLGGMLTNFTTIKTRINRLNKLDEMEQDGTFDVLPKKEVIKLKLEREKLQRNLGGIKELDASNIGAMFVVDPRKEKNAIAEAKILGIPVVAIVDTNCDPEEVDYVIPGNDDAIRAVKLIAGKMADAIIEGRQGEQLAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS3_PYRHO
Sequence: MAIERYFIREAVKEMLIDEFLEKELRRAGYGGLDIKKTPLGTKVIIFAANPGYVIGRGGRRIRELTRILERQFGLENPQIDVQEIKNPYLNAKVQAVRIAQALERGIHFRRAAYSAMRAIMNNGARGVEIRLSGKLTGERAKSVRFYQGYLAKVGNPAETLVSKGYAQALLKLGVIGVKVAIMPPDARLPDEIEIVEKPAEEEVSTNEAE
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NRDI_MYCMS
Sequence: MHSNVKKVTDKDVIKPVGIPFVVYFSSISNNTHRFIQKLEIENIRIPYELDQSISVNRDYVLVTPTYSGGGEYVEGAVPKQVIKFLNNKENRSFCRGVISSGNTNFGDTFGIAGPIISKKLNVPFLYQFELLGTQHDVSQIKQILFRFWEDGNNERK
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: RL5_FRATW
Sequence: MARLKDYYQKELVAKLKTELGLDNIMEVPAIKKITLNMGVGDAAKDKKIMTFALNDLTAIAGQKPVVTKSKKSIAGFKIRDGWPIGAKVTLRGDRMYEFLDRLITIAIPRIRDFRGLSAKSFDGRGNYSLGMREQISFPEIDYDKVDSIRGLDISITTTAKNDDQGRALLKAFGFPFKS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: INS_TRASC
Sequence: AANQHLCGSHLVEALYLVCGERGFFYSPKAGIVEQCCHNTCSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: XPT_ALKMQ
Sequence: MELLKEQIREVARVEKGNVLKVDSFLNHQLDIPLLNEIGKELKKRFQGEKVDKILTAEVSGIAIAAIAAQYFNVPVVFAKKTQSKNLDQDTYEGEVYSYTKGQAYKIRVSKRYLHEKENILIIDDFLANGEALQGLREIVVQANANLVGAGIVIEKGFQGGGKRLRAENMRIESLAIIDEMNESTLVFRDDKADLKADPKAS
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4159_BACAN
Sequence: MASETVSNHQEKALALLQADAEKILRLIKVQMDHLTMPQCPLYEEVLDTQMFGLSREVDFAVRLGLIAEEQGKVMLGELERELSALHEAFTNKQQ
What are the official names of this protein?
UPF0358 protein BA_4159/GBAA_4159/BAS3861.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: Y7023_PSEAB
Sequence: MSIRDWPEAERPREKLLEQGAAALSDAELLAIFLRTGVTGCSAVELSRRLLSEFGGLRALLEADLASFCGHLGLGVAKYAQLQAVLEMGRRHLAERLRRDSILESPQAVRDYLKARLRHEQHEVFACLFLDTRHRVLAFEVLFQGSIDGASVYPRQVVKRTLAHNAAALILTHNHPSGDARPSLADRQLTARLKEALALIDVRVLDHFIIGDGEPLSLAEYGWL
What are the official names of this protein?
UPF0758 protein PA14_70230.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: LIPA_KLEP3
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSSRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPQKLAQTIADMGLRYVVVTSVDRDDLRDGGAQHFADCISAIREKNPSIKIETLVPDFRGRMDRALDILTVTPPDVFNHNLENVPRLYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNDEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPEEFEEMKAEAMAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFIIS_ASFK5
Sequence: MKMHIARDSIVYLLNKHLQNTILTNKIEQECFLQADTPKKYLQYIKPFLINCMTKNITTDLVMKDSKRLEPYITLEMRDIIQMMFFRTLQKHTFFRENTNLCTEYVQKIEASCYHYTYQQQEKTFLEEYSTRCGMINHIINCEKKSHQQQDNDALNKLISGELKPEAIGSMTFAELCPSAALKEKTEITLRSQQKVAEKTSQLYKCPNCKQRMCTYREVQTRALDEPSTIYCTCKKCGHEFIG
What is the function of this protein?
Putative initiation factor.  Necessary for efficient transcription elongation past template-encoded arresting sites.
What are the official names of this protein?
Transcription factor TFIIS homolog.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family.
Protein: PRO_ADEO7
Sequence: MSGTSESELKNLISSLHLNNGFLGIFDCRFPGFLQKSKIQTAIINTGPREQGGIHWITLALEPISYKLFIFDPLGWKDTQLIKFYNFSLNSLIKRSALNNSDRCITVERNTQSVQCTCAGSCGLFCIFFLYCFHFYKQNVFKSWLFQKLNGSTPSLIPCEPHLLHENQTFLYDFLNAKSVYFRKNYRTFIENTKTGLIKTH
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: ISPE_BACVZ
Sequence: MRILEKAPAKINLSLDVTSKRPDGYHEVEMIMTTIDLADRIELTELPENVIRVASHNRFVPDDQRNLAYQAAKLLKERFQVKKGVSIMITKVIPVAAGLAGGSSDAAATLRGLNRLWDLKLSVEELAELGAEIGSDVSFCVYGGTALATGRGEKIRHISAPPHCWVVLAKPTIGVSTAEVYRRLNLQQVRHPDVQAMIDAIEEKSFQKVCGQLGNVLESVTLSLHPEVAMIKNQMKRFGADAVLMSGSGPTVFGLVQYESKVQRIYNGLRGFCDQVYAVRMIGEQNALD
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RL30_LEGPH
Sequence: MGKKIKITLVKSTIGRKPKHVAIAKQLGLGKTNSSVVHSDTPAIRGLVNEINYLLLVEESA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: IL2RA_SHEEP
Sequence: MEPSLLMWRFFVFIVVPGCVTEACHDDPPSLRNAMFKVLRYEVGTMINCDCKAGFRRVSAVMRCVGDSSHSAWNNRCFCNSTSPAKNPVKPVTPGSEEQRERKPTDAQSQTQPPEQADLPGHCEEPPPWEHEREPLKRVYHFTLGQTVHYQCAQGFRALHTGPAESTCTMIHGEMRWTRPRLKCISEGANSQAPDEAEPPESTEAPPGSGTFLTTRMAGTTDFQKPTDVVATLDTFIFTTEYQIAVAGCILLLSSILLLSCLTWQRRWKKNRRTI
What is the function of this protein?
Receptor for interleukin-2.  The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.  TREGs suppress the activation and expansion of autoreactive T-cells.
What are the official names of this protein?
Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: YB5A_THEMA
Sequence: MIPPHIHILDFNGIYEEQRILKSLAEFVFSKKIEGIRYMVLPEKIPEIENILPSHLGVTFLGDGEFHHLTYFIIKKIKRPFVLVVFDNHLDAREEEFLTCDSWIRKALKLKHLVKVVVVGTQEQEKIHRVFYSETDPQKILKLLGRHPVYLSIDKDVLDIGITGWESGRVSLEDLLNVLRHIPLRKILGADICGEPDPLEFWKMQESEKVNLSILSALFFEKLHYVPGSEHLEGKPAHVT
What are the official names of this protein?
Uncharacterized protein TM_1158.1.
Protein: RSMA_HALH5
Sequence: MTKDIATPIRTKEILAKHGFTFKKSLGQNFLIDPNVLRNIVDVASLTPQSGAIEIGPGIGALTEQLARQAKRVVAFEIDQRLIPVLRETLAPYENVTVINEDVLKADVKQVIATTFEEGQDLMVVANLPYYVTTPILMKLLEAKLPVRGIVVMIQAEVADRIAAKPGTKEYGSLSIAAQYYATAELAVKVPKTVFVPQPNVDSAVLRLTIREKPPVTVADEEWLFAIVRASFANRRKTILNNLIHNLVGKERKDKAVQALAEAGIDPSRRGETLTIEEFANLSEQLQKR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
Protein: NIFVO_CLOPA
Sequence: MAVVMDGVKKNIIDRTIPNLVKKFQNFNNDDIAYFLKLLHETGIDLFEINRDSMDKIKKFPLNLDYIYRIENIEDYNYLNNYNFKYIILNYKTIYRFLLEDEKIQKNLKEHNIILEIDIEDLDELYLSEDNKIFCIFNIVCLRINNLSKLDFIDEDFRIKDLKSKFNVLVDFCASNKYNMATAIIINAFLNGSDIITTEFNSNDYAAMEEVIIALKSIRNIEIRGDLKLISKLTRIYEKITSERVYSMKPILGEDIFKYESGIHADGIAKNPKNYEPFNPELIGTNRKLYIGKHSGKAALVVKFKELNLNCNNIDMNLFLQDIREKSIQEKRNVLDNEIIEMYKEYNKSYQR
What is the function of this protein?
This protein is a Fe-Mo-cofactor biosynthetic component.
What are the official names of this protein?
Homocitrate synthase, omega subunit.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.