PharMolix/UniProtQA huggingface dataset:
Protein: MUKB_ECO27
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEFLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKIQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLNQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: ATPE_RHIEC
Sequence: MADNFNFELVSPERLLLSEMVTEVVVPATEGEMTVMANHAPTMTTIKPGVVSVRSASGKKQDYVVFGGFADILPTGCTLLAESAVPVEELHKDELTRRIEAARKELEHAELHEHKSRLEHFIMELTHLRGIVQQD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ODO1_BACP2
Sequence: MFQNDVKQPLSWEEFHGPNLGYVLELYDQYVQDPTSVDEDLRGIFDELGAPPSEMKEEIGKKENSVVTSEQIQKIASVVKLAEDIRTYGHLNASVNPLRKEKELQELFPLKEYGLTEEDVKNIPISIISPDAPKHISNGIEAINHLRNTYKRTISFEFDHVHDFEERNWLSKSIESGELFKKKPADKLVSVFKRLTEVEQFEQFLHKTFVGQKRFSIEGLDALVPVLDEIISESVTQGTSNINIGMAHRGRLNVLAHVLGKPYEIIFSEFQHAPNKELVPSEGSIGISYGWTGDVKYHLGADRQIKDEDTKSARVTLANNPSHLEFIDPIIEGSTRAAQELRTQKGYPAQDVEKALAILIHGDAAFPGEGIVAETLNLSQLVGYQVGGTIHIIANNMIGFTTESNESRSTKYASDLAKGFEIPIVHVNADDPEACLAAVQLAVEYRKRFKKDFLIDLIGYRRYGHNEMDEPSTTQPMLYDAVRKHKTVKNIFADKLVSEGLLTKEQREEIEQAVATRIEEAYQKVPSKKEHTIQEIELPEPVSNGFPAVDTSVEFDVLRKLNEELISWPDDFQVFGKLKRILEKRAKVFTDDRKVEWSLGEALAFASILKDGTPIRMTGQDSERGTFAQRNLVLHDSQTGNEFIALHELSDANASFTVHNSPLSEGSVIGFEYGYNVYSPETLVIWEAQFGDFANAAQVYFDQFISAGRAKWGQKSGLVMLLPHGYEGQGPEHSSGRTERFLQSAAENNWTVANLTSAAQYFHILRRQAKMLLREEIRPLVIMTPKSLLRNPNSLSEVQELTDGQFQPVLEQPGLVHDHEKVSRLVLSSGKVSIDISDRFTQMEEPKDWLHIARVEQLYPFPAKDIKAILSKLTNLEEIVWTQEEPQNMGAWGYIEPYLREIAPEKVKVRYIGRRRRSSTAEGDPTVHKKEQERIVSDSLTRKN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: SLBB_TRIAB
Sequence: MGRFIFGSFGLLVLFLSLSGTGADCPSDWSSYDLYCYKVFQQRMNWEDAEQFCRQQHTGSHLLSFHSSEEVDFVVSKTLPILKADFVWIGLTDVWSACRLQWSDGTELKYNAWTAESECIASKTTDNQWWTRSCSRTYPFVCKLEV
What is the function of this protein?
Weakly agglutinates platelets at high doses by binding to GPIbalpha (GP1BA).
What are the official names of this protein?
Snaclec alboaggregin-B subunit beta, AL-B subunit beta, 25-kDa alboaggregin.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: FIS_VIBA3
Sequence: MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVSELYELVLAEVEQPLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: NNRD_CAEBR
Sequence: MDHFLKLLPKLTPQLRKGDCGKIAVIGGSLEYTGAPYYAASSVSRLGADLIHVFCAPDAAPVIKGYSPDLIVHPGMNASSILPKLNRMDAIVVGPGLGRNPTLWPLLQEIFNFVKNEKVPFVIDGDGLWFVSEHIEHFPRQMVTTVLTPNIVEFSRLCKSALGEEDVLNVKSSSQLQHLAAELSRKMDVTIYMKGEVDLVVTPNGEVSKCSTDSSLRRCGGQGDVTAGSLGLFLYWAKKNLGDDWTSAHHEAGISSSWLVRTAGRRAFEKHGRSMNTPLLLDEIPKLVRDVETREMKDTVHSDSSKH
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: Y885_BRUME
Sequence: MKNLFRTAALMVPLSLALAYGAQAKEIPIGKPQLLGGMEIAAVYLQPIEMEPEGMMRPAKDSDVHLEADIKAAKDNTNGFAEGDWVPYLVVSYELTHLDNGKVQKGDFMPMVANDGPHYGDNVKLDGPGKYKLKLFVSPPSANQHAHFGRHVDKETGVGPWFKPVTAEYEFVYAGTGKKGAY
What are the official names of this protein?
UPF0423 protein BMEII0885.
What is the protein family that this protein belongs to?
Belongs to the UPF0423 family.
Protein: EEDB_XENLA
Sequence: MSEASGRAAGNEMPAKKQKLSSDENSNPELSGDENDDSVSIESGTNTERPDTPTNAANAPGRKGWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHPQGDIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSLRMKTAIKESYDYNPNKTNRPFVSQKVHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIEKIKASESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTYPKCASAIRQTSFSRDSSVLIAVCDDSTIWRWDRLR
What is the function of this protein?
Polycomb group (PcG) protein.  Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity).  May play a role in neural induction.
What are the official names of this protein?
Polycomb protein eed-B, Xeed-B, psXEED.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ESC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRR_THEPX
Sequence: MKIKAEIMDEKAIDRALIRIAHEIVERNKGIEDVVLVGIKTRGVPLAERIAKYISRIEGKKPPVGSLDITLYRDDLTTDLEQPLVKKKDIGVDVVGKIVVLVDDVIYTGRTIRAAMDAIIDLGRPKAIQLAELIDRGHRELPIKPDYVGKNVPTSKNEIVNVMLEEVDKVNRVVITEK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: LEP_STRPN
Sequence: MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLADGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDEPYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPEGEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: YNG2_ASHGO
Sequence: MSFERPQDPSSALEQATQDVSNLKSESRFLLEEIRASDLEFYESKKRFLNKDTQIHKFIKQHGSLVDNPKEAEFQERIKEDLERCHQLQVDKCTVANSLLYMVTKHLKKVQANIEALEEDGLLAPLEDDAVELANELSRESSVLSSGTSLERRKRTVAAGTLSAGSSLRKRVKKERGRSTQRDGMLSEPPSDEASSHGANFADDLQDFNDELFSLNQQEEDDKQLYCFCQSVSYGEMVACDGPNCKYEWFHYGCVNLDEPPKGQWYCPECRQEMANLKLKKKKRV
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Involved in cell cycle progression and meiosis (By similarity).
What are the official names of this protein?
Chromatin modification-related protein YNG2, ING1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the ING family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MP_MSVK
Sequence: MDPQNALYYQPRVPTAAPTSGGVPWSRVGEVAILSFVALICFYLLYLWVLRDLILVLKARQGRSTEELIFGGQAVDRSNPIPNIPAPPSQGNPGPFVPGTG
What is the function of this protein?
Involved in the viral transport within, and between cells.
What are the official names of this protein?
Movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the mastrevirus movement protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: KCNKG_HUMAN
Sequence: MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDFPISKKGLGS
What is the function of this protein?
Outward rectifying potassium channel.  Produces rapidly activating and non-inactivating outward rectifier K(+) currents.
What are the official names of this protein?
Potassium channel subfamily K member 16, 2P domain potassium channel Talk-1, TWIK-related alkaline pH-activated K(+) channel 1, TALK-1.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISCS_ACIB3
Sequence: MKRPIYLDYAATTPVDPQVAERMMECLTFDGTFGNAASRSHAYGWQAEEKVEYAREQVANLIKADPREIVWTSGATESDNLALKGVAQFYASKGKHIITSKIEHKAVLDPCRELEEQGFEITYLEPEPQTGLITPEMVKAALRPDTILVSLMMVNNEIGTVTDVAAIGELTRANKTFFHVDAAQAAGKVDIDLSTMKIDLMSFSAHKIYGPKGIGALYVRRSPRVRLKAQIHGGGHERGMRSGTLATHQIVGMGEAFELAGKTMHAEQERIRKLRDKLWNGLQDLEQVFLNGHPTQNVANYLNVSFNFVEGESLMMSLKDAAVSSGSACTSATLEPSYVLRALGLSDELAHSSIRFSFGKYTTEEDIDHVLTITKAAVEKLRELSPLWDMYKEGIDLSTVEWAEH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5M_OSPRO
Sequence: MNFIFNSSMLLAITMLTFPLIYNLAFPDKTNNFPLYCKTTVKMAFFTSLPALLLFINTGQESTITNWQWFSIESLNMTMSFKLDYFSIIFIPIALYVTWSILEFSLWYMHSDPYIHRFFKYLITFLLTMIILVSANNLFQLFIGWEGVGIMSFMLIGWWFGRTDANTAALQAVLYNRIGDIGFMLAMAWLMINNSSWDLQHIFMTNMDTLALMGLVIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFHPMIKDNPTILTTTLCLGAITTLFTAICAITQNDIKKIVAFSTSSQLGLMMVTIGLNQPYLAFLHICTHAFFKAMLFLCSGSIIHNLNDEQDIRKMGGLLNIMPITSSALITGSLALMGTPFLAGFYSKDSIIEAMNTSHTNTWALIITLIATALTAIYSLRIIYFALLNQPRFLPMSPINENHPNLTNPIIRLAMGSIFAGFILTMNIPPTSMVPLTMPPISKLSALIVTITGLLIAMELNSATNKSLMMSYIHTHNFSNMLGYFTYLFHRMYPLANLYLGQHIATMLIDLNWYEKTGPKGQANLHSTISSYISSTQKGLIKTYFLSFIISIPMIMLII
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRPD_RUEPO
Sequence: MSDALKPLIGAAADRPLTRAEAEQAFTILFDGEATPSQIGGLLMALRTRGETVDEYAAAAAVMRAKCNAVRAPEGAMDIVGTGGDGKNTLNISTATAFVVAGAGVVVAKHGNRNLSSKSGTADLQGQMGINVMVGPQVVEKALNEAGIGFMMAPMHHPATAHVMPTRAELGTRTIFNILGPLTNPAGVKRQLTGAFTRALIRPMAETLGLLGSERAWLVHGSDGTDELTITGVSWVAALEDGTVKEVELHPEDAGLPVHPFEAIIGGTPEENATAFRALLDGAPSAYRDAVLLNAAAALVVADRAADLREGVALAAQSIDSGQARAKVEALSRITQDAR
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CYAY_ACTSZ
Sequence: MNVAEFHQNIDQLWDSIEEQLEAQDADADCDRQGSVFTITFDDRSQIVVNKQEPLLELWLASRLGGLHFAWKNNDWVNGQGVRFWDALTEACQAHGEQVSFI
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: AKRMG_ECOLI
Sequence: MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSEGKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREMAEALER
What is the function of this protein?
Catalyzes the NADH-dependent reduction of methylglyoxal (2-oxopropanal) in vitro (PubMed:16813561).  It is not known if this activity has physiological significance (PubMed:16813561).  Cannot use NADPH as a cosubstrate (PubMed:16813561).  Seems to play some role in intestinal colonization (PubMed:20562286).
What are the official names of this protein?
NADH-specific methylglyoxal reductase, AKR11B2.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 11 subfamily.
Protein: TAM_ECOHS
Sequence: MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPDNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARRME
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP1B1_BOVIN
Sequence: MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKESDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes.  The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).
What are the official names of this protein?
AP-1 complex subunit beta-1, Adaptor protein complex AP-1 subunit beta-1, Adaptor-related protein complex 1 subunit beta-1, Beta-1-adaptin, Beta-adaptin 1, Clathrin assembly protein complex 1 beta large chain, Golgi adaptor HA1/AP1 adaptin beta subunit.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: MURB_ANOFW
Sequence: MEKLREELLQANVGTVKENERMASHTTIKIGGPADLFVEPKHIDGLKKTMEIVRKYNVPWRAIGRGSNLLVRDGGIEGVVIKLGEGLDDLYIHDTEVTVGGGYSLIKLATVISKQGLSGLEFAGGIPGTVGGAVYMNAGAHGSDMSRIVKKAQILFEDGTIEWLTNEEMEFSYRTSVLQKKRKGICIAATLEMKKGNHDEIVAAMQKNKDYRRETQPWNYPCAGSIFRNPLPQYAGQLIEQAGLKGYTIGGAKISEQHANFIVNAGGATANDVLELIDYVKKTIYDLYGVSLQTEVEIVGRK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMEL_BOVIN
Sequence: MDLVLRKYLLHVALMGVLLAVGTTEGPRDRDWLGVSRQLRIKAWNRQLYPEWTESQGPDCWRGGHISLKVSNDGPTLIGANASFSIALHFPKSQKVLPDGQVIWANNTIINGSQVWGGQLVYPQEPDDTCIFPDGEPCPSGPLSQKRCFVYVWKTWDQYWQVLGGPVSGLSIGTDKAMLGTYNMEVTVYHRRGSQSYVPLAHSSSAFTITDQVPFSVSVSQLQALDGRNKRFLRKQPLTFALQLHDPSGYLAGADLSYTWDFGDSTGTLISRALTVTHTYLESGPVTAQVVLQAAIPLTSCGSSPVPGTTDRHVTTAEAPGTTAGQVPTTEVMGTTPGQVPTAEAPGTTVGWVPTTEDVGTTPEQVATSKVLSTTPVEMPTAKATGRTPEVSTREPSGTTVTQGTTPELVETTAGEVSTPEPAGSNTSSFMPTEGTAGSLSPLPDDTATLVLEKRQAPLDCVLYRYGSFSLTLDIVQGIESAEILQAVSSSEGDAFELTVSCQGGLPKEACMDISSPGCQLPAQRLCQPVPPSPACQLVLHQVLKGGSGTYCLNVSLADANSLAMVSTQLVMPGQEAGLRQAPLFVGILLVLTALLLASLIYRRRLMKQGSAVPLPQLPHGRTQWLRLPWVFRSCPIGESKPLLSGQQV
What is the function of this protein?
Forms physiological amyloids that play a central role in melanosome morphogenesis and pigmentation.  The maturation of unpigmented premelanosomes from stage I to II is marked by assembly of processed amyloidogenic fragments into parallel fibrillar sheets, which elongate the vesicle into a striated ellipsoidal shape.  In pigmented stage III and IV melanosomes, the amyloid matrix serves as a platform where eumelanin precursors accumulate at high local concentrations for pigment formation.  May prevent pigmentation-associated toxicity by sequestering toxic reaction intermediates of eumelanin biosynthesis pathway.
What are the official names of this protein?
Melanocyte protein PMEL, Melanocyte protein Pmel 17, Premelanosome protein, Retinal pigment epithelial-specific protein, Silver locus protein homolog.
What is the protein family that this protein belongs to?
Belongs to the PMEL/NMB family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus. Melanosome. Endosome, multivesicular body. Note=Localizes predominantly to intralumenal vesicles (ILVs) within multivesicular bodies. Associates with ILVs found within the lumen of premelanosomes and melanosomes and particularly in compartments that serve as precursors to the striated stage II premelanosomes (By similarity). SUBCELLULAR LOCATION: [M-alpha]: Secreted.
Protein: TXG3A_ETHRU
Sequence: MNTVSVVQFLAVVCAVFVLYGRGVFAAEGVKKAGQHKDAELCLGSDGLGHRLDEFWYNDDMCQRFLCFKDDEGIMYEQIANCPIAIAEGDCTLKPGTKGHYPDCCPAVECPPEDQKEGEI
What are the official names of this protein?
U-scoloptoxin(16)-Er3a, U-SLPTX(16)-Er3a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: 3DHQ_CANDC
Sequence: MVKKVLLINGPNLNLLGTREPEKYGTTSLSDIEQAAIEQAKLKKNDSEVLTFQSNTEGFIIDRIHEAKRQGVGFVVINAGAYTHTSVGIRDALLGTAIPFIEVHITNVHQREPFRHQSYLSDKAVAVICGLGVYGYTAAIEYALNY
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase, cDHQase, 3-dehydroquinate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: WN2BB_XENLA
Sequence: QECKCHVSGSCTLRTCWRALSDFRRTGDYLRRRMNGAVQVMATQDGANFTSARQGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCC
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt/beta-catenin signaling pathway.
What are the official names of this protein?
Protein Wnt-2b-B, Protein Xwnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: YFVA_SCHPO
Sequence: MNMPSEILLGARRWFASTSFSLAAVYDAPLKKAIGNIKKFSIGSLGLTYMISPVMLLLDAGGLSLGTRMSMVFLACTTTSLSTAIIHWAAKSYVSEATLKGNVLSLNTFNILGKKRLSQYTLDKLKIPDTNNSRPFANLESTTVPKRYFYLHPELATPIFNAIRQAQQPKQINKNDSK
What are the official names of this protein?
Uncharacterized protein C1834.10c.
Protein: CAF17_YEAST
Sequence: MFISRRCRIKGFTLKNLLWFRSSSTRFVSTESPDASAITKPDGIFNYSLLENRTYIRIRGPDTVKFLNGLVTSKLLPHFIKKNLTTVEENEVPTEEGTTKVDPIIPVPEFDARLGNWGLYNEKGIQGPYISRFGLYSAFLNGKGKLITDTIIYPTPVTVSEQISNYPEYLLELHGNVVDKILHVLQTHKLANKIKFEKIDHSSLKTWDVEVQFPNLPKDIENPWFDNLLDPMALPKNSIDANNFAVNVLNSLFNSDPRILGIYVERRTESMSRHYSTFPQSFRVVTSEQVDDLSKLFNFNVFDFPFQVNKKASVQVREIRFQKGLIDSTEDYISETLLPLELNFDFFPNTISTNKGCYVGQELTARTYATGILRKRLVPVKLDNYQLLDTDPERKYAEFHIDNVVEKSLAENEPTLNPFTNKPPERTKRKQRPAGLLISNEGLYGVALLRTEHFSAAFSSDEPVEFYITTTKGENIKITPQKPFWFSDWKNNNGPHK
What is the function of this protein?
Required for lysine and glutamate prototrophy and mitochondrial genome maintenance.  Has a role in the maturation of mitochondrial aconitase-type and radical-SAM Fe/S proteins biotin synthase and lipoic acid synthase.
What are the official names of this protein?
Putative transferase CAF17, mitochondrial, 57 kDa iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins, CCR4-associated factor 17.
What is the protein family that this protein belongs to?
Belongs to the GcvT family. CAF17 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.