PharMolix/UniProtQA huggingface dataset:
Protein: LIPO_RHIMB
Sequence: MKGLVLSFALVALSALCVYGDVPIQPDFQEDKILGKWYGIGLASNSNWFQSKKQQLKMCTTVITPTADGNLDVVATFPKLDRCEKKSMTYIKTEQPGRFLSKSPRYGSDHVIRVVESNYDEYTLMHTIKTKGNEVNTIVSLFGRRKTLSPELLDKFQQFAKEQGLTDDNILILPQTDSCMSEV
What is the function of this protein?
Might have a transport function across the blood brain barrier.  Is supposed to have similar functions as transthyretin which must have evolved after the stage of the amphibians in evolution.
What are the official names of this protein?
Lipocalin.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted. Note=Found in cerebrospinal fluid.
Protein: GHRB_ECOUT
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXX_RHILP
Sequence: MTVAVTNIRVEDKLYQNRYVVDAGRPHIRVRPHDWPSVNLYALTSVCPAKCYELNDQGQVEVIADGCMECGTCRVLCEASGDIEWNYPRGGFGVLFKFG
What is the function of this protein?
Could be a 3Fe-4S cluster-containing protein.
What are the official names of this protein?
Ferredoxin-like protein.
What is the protein family that this protein belongs to?
To ferredoxins from P.putida and C.tartarivorum, ferredoxin I from A.vinelandii, ferredoxin II from D.desulfuricans.
Protein: ZN252_CANLF
Sequence: MAVKQLLPAGSQVLVSFEDVAVLLSREEWGRLGPAQRGLYSDVMLETYRNLISLGLQGSKPDVISRLEKGEEPWAPYSAKIEESWIRSHESESFQSLMEKKGLTPKQEISKAMGFRRAKSEYVRNVSKESEFEEMNKTKGKLKNYRKKSAEEELKKSFSQKNSSRPVTLTHVKSPVSGKGQKSSSLEVDYTVDASPVRFHRASTGGSLHQNVPCVNDFQQSQDLINLQCLHLGERACQTDLFMKAPRQSSVLSENQRVNNPEKSFECTECRRLFSPSKALSQHQRSHTGEIPCESGGCGRTSHHCSVLSQHQEVHHGGESHTCAECGKAFKAHSYFIQQHNTHTGERPYECSECAHLSYSQHLQIHSGQKPHECSQCGKAFSHSSNLFHHQRIHSGEKPYECKECGKAFGRHSHLLQHKRIHSGEKPYDCTECGKAFSARLSLIQHQRTHTGEKPYECNECGKSFSLNRTLIVHQRIHTGEKPYRCNECGKSFSQRAQVIQHKRIHTGEKPYVCNECGKSFSARLSLIQHQRIHTGEKPYGCSECGKTFSQKGHLIQHQRIHTGEKPYECNECGKAFSQSFNLIHHQRTHNGEKPYECNECDKAFSVLSSLVQHQRVHNGEKPYECHKCGKAFSQGSHLIQHQRSHTGEKPYECNECGKTFGQISTLIKHERTHNGEKPYECGDCGKAFSQSAHLVRHRRIHTGENPYECSDCGKAFNVRSSLVQHHRIHTGEKPYECEKCGKAFSQHSQFIQHQRIHTGEKPYICNECEKAFSARLSLIQHKRIHTGEKPYKCTECGKSFRQSSHLIRHQRVHSGERPYMCNECGKTFSQRITLTSHEKTHTREQAYKCVKREDLLTAQSASIQHHKVHNGE
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 252.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAL_STRA3
Sequence: MKYFLDTADVSEIRRLNRLGIVDGVTTNPTIISREGRDFKEVINEICQIVDGPVSAEVTGLTCDEMVTEAREIAKWSPNVVVKIPMTEEGLAAVSQLSKEGIKTNVTLIFTVAQGLSAMKAGATFISPFVGRLEDIGTDAYALIRDLRHIIDFYGFQSEIIAASIRGLAHVEGVAKCGAHIATIPDKTFASLFTHPLTDKGIETFLKDWDSFKKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAGK_AGRFC
Sequence: MRQASVLAPHTNGPTVTAGEILVEIMATTVGDGFLEPQTLIGPFPSGAPAIFIDQVARCGGTAGIIAAVGDDDFGRLNIERLRRDGVDVSAITTIADRPTGSAFVRYRENGARDFVFNIAHSAASETRMTDEAQALIEKAGHVHIMGSAFAIAGIGAIILEAVKSVKARGGSVSFDPNIRKELAQGDEGRRLIDDLLAVTDLLLPSGEELQAASGLDDEEAAIEKLLAAGIGEIVLKRGANGASHFSRAHGRIDAPGLEVEEIDPTGAGDCFGATYLTCRRLGMRPGKALVYANASGAHNVTKRGPMEGAASLAELDAFMAAQLSEEVL
What is the function of this protein?
Involved in galactitol and D-altritol catabolism.  Catalyzes the phosphorylation of D-tagatose to D-tagatose 6-phosphate.
What are the official names of this protein?
Tagatose kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: YWPF_BACSU
Sequence: MKTFKLVDLNVERVDKEEQSIEQFPLIDGLIINKEDGENHWLIEALVQKEHLSFFEQLQNSQSEAKVFVTITKKSNRPAQLTAAVKNIVKLEESIQVLLYGQMVTRKQQGTETILESLVKEGYTGTKLIEAFKQKL
What are the official names of this protein?
Uncharacterized protein YwpF.
Protein: RS211_TRIV2
Sequence: MAEVRLGENESIDSAIRRFKKKIQKAGILSEVKRRERYEKPSLRRKRKAEAARKGGRN
What are the official names of this protein?
30S ribosomal protein S21 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: SFGH_PARDP
Sequence: MTLAYETVSENRSFGGIQGVYRHQSQATGTPMTFAIYLPPDARHGKVPVLWYLSGLTCTHENAMTKAGAQEWAAEYGIAVIFPDTSPRGEGVANDETYDLGQGAGFYVDATEAPWAPHFRMWHYVTHELPELVFNNFPLDREAQGITGHSMGGHGALTIAMTFPERYRSVSAFAPIAHPSESDWGRKQFAAYLGDDKAAWKRHDSTILMREKGYPGEVLIDQGASDQFLDLLKPEALAHAMAERRQPGTFRMQQGYDHSYFFVQSFMADHIRWHAERLG
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (Probable).
What are the official names of this protein?
S-formylglutathione hydrolase, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: SPA11_RAT
Sequence: MGPVWLWLLIAELLLPVHYQPSSAHGDKSLGAPQPASHQSLEPAPAYHKVTPTITNFALRLYKQLAEEIPGNILFSPVSLSSTVALLSLGAHADTQAQILQSLGFNLTETPAADIHRGFQSLLHTLDLPSPKLELKLGHSLFLDRQLKPQQRFLDSAKELYGALAFSANFTEAAATGQQINDLVRKQTYGQVVGCLPEFDRDTLMVLLNYIFFKAKWKHPFDRYQTRKQESFFVDQRLQLRIPMMRQKEMHRFLYDQEASCTVLQIEYSGTALLLLVLPDPGKMQQVEAALQPETLRRWGQRFLPSLLDLHLPRFSVSATYNLEEILPLVGLSSLFDVEADLSGIMGQLNKTVSRVSHKAVVDMNEKGTEAAAASGLLSQPPSLNMTSAPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPAAG
What are the official names of this protein?
Serpin A11, Liver regeneration-related protein LRRG023.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2085_MYCTU
Sequence: MSDMCDVVSFVGAAERVLRARFRPSPESGPPVHARRCGWSLGISAETLRRWAGQAEVDSGVVAGVSASRSGSVKTSELEQTIEILKVATSFFARKCDPRHR
What are the official names of this protein?
Uncharacterized protein Rv2085.
Protein: TRMFO_BEII9
Sequence: MPSPIHVIGGGLSGAEAAWQIAKAGIPVILHEMRPDRSTPAHHSADLAELVCSNSFRADDAESSAIGILHREMRRLDSLILQAADCNRLPAGGALAVDRQGFAAFVTAAIKASPLITLVRGEVTEIPADWDQIIIATGPLTSETLAAHIKALTGEDDLAFFDAIAPVVYRDSIDMTKAWFQSRYDKVGPGGNGADYINCPLDKEQYQAFVEGLIQGEKISFKEWEGTPYFNGCLPIEIMAERGPETLRHGPMKPVGLTNAHAPTVKPYAIVQLRQDNALGTLYNMVGFQTKLKHAEQIALFRTIPGLEQARFARLGGLHRNIFLNTPKVLDMRLRLKADPRLRFAGQITGCEGYVESAGIGLLVGRMAACERLGESFVPPPTTTALGALLNHITAGHIETIDAGPRSFQPMNVNFGLFPPLTEKIVSPEGKRLRGPEKDQLKKRLLSQRAERDLEAWCTAPTCGPTPLAAE
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_STRPC
Sequence: MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIKEICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGIKTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEIIAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_MYCGI
Sequence: MPDPATYRPAPGSIPVEPGVYRFRDPHGRVIYVGKAKSLRSRLNSYFADISGLAPRTRQMVMTASSVEWTVVGTEVEALQLEYNWIKEFDPRFNIRYRDDKSYPVLAVTLNEEYPRLKVYRGPRRKGVRYFGPYSHAWAIRETVDLLTRVFPARTCSNGVFKRHSQIDRPCLLGYIDKCSAPCVGRVSAEQHRQIVQDFCDFLAGKTDRLIREMEQQMTAAAEDLDFERAARLRDNIGAMRRAMEKQTVVLGDGTDADVVAFADDELEAAVQVFHVRGGRVRGQRGWVIEKSGEPGESTLEYLVEQFLTQFYGDQAELGGASDAGGDEASNPVPKQVLVPVLPETTDELETWLSQLRGSRVALRVPQRGDKRALAETVKRNAEGALNQHKLKRAGDFTARSAALQSIQENLGLQDAPLRIECIDISHVQGTDVVASLVVFEDGLPRKSDYRHFAIREAAGDGRSDDVASIAEVTRRRFHRHLRDMQEPGEMVAEGRSRRFAYPPNLFVVDGGAPQVNAAQAVLDDLGISDVAVIGLAKRLEEVWVPNLDGTAPDPIIFPRNSDGLYLLQRVRDEAHRFAISYHRSKRSKRMTASALDSVRGLGEHRRKALVTHFGSLARLKQATVEEITEVPGIGAATARAVLDALGIEAPPEPGAEAPPDSGAAAAVMGNDQSRVPG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_HALH5
Sequence: MKRIPSIRERNIVLIGFMGVGKTSVGEQLAKRLFRDFIDVDQEIEKTWKMKISDIFRLKGEEAFRKIEREMTIDYCTNTSLKVISLGGGAYMQDAIRTACLDHCIVIYLDLSWSLWKERLNVLIDNRPVLQDKKVEEMEQLFTKRQPTYQKNSFQVETDGREVAEIVSYLEEVIKLGWEIYGS
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
Protein: TWK12_CAEEL
Sequence: MTLFKKIQWFCNLIRLRSYYKFLLLIAYTAFGAWLFRTYELQADIKRRSVFGNTTNLVRRQLAERWIEMHKDAVLRNDSALRFRRAAEAVEWLLDELNLSDHIRDLSEETPWTWTGAMFYAGQLYTTIGYGYPTTKTDEGRICTIFYALFGIPCFLMYLKIENAIEWKKDKQLGKRALKMHGLINDSFQSIGKTLSKKMKKYYKKLRRSRVGRILLPTRVTAMKDGFEDPEAAEERKKKPFPIPIAIIMLIIWICFSASMFCIWEDTWVFSSAVYFFIVSISTVGLGDMLFRTPDMMVFNFLLILVGLALLSMCFELITDRVAKWKQKRFDEHIKKVQKMAFQVFEKDPFIEEAPPLGIRMAPNLMQIAATHVSEEKRGFFAEFKDWFAGKVTDNVIQSKLEDSDDESDSEEALEEFDSPQIATVTANDLIVCSNGAATRRVSKQSYALSDISNLSNSKILPGNNYGQLLDRIKAMEKFKPKKNDLDSRMFAKFLENKKLAKILEQTELRELATVSCQTDLSGLVVQRRNPKGRHARIGSCSSQSTMSTLLPNKMHAPDEDSVMSFTFGDLKFDYKTEPFIDEYYIRESNHSIFDFDEDETVRIPQKMLISRPGMPPPPPSRPLNLASPLRTLLEKEQKYDEDPEIQLTPRRLNSLSDIQARKVKLGVDENLQHARLVCGLLPQDFDSPSTSTSTSMIDSGYELSKRDASTMA
What are the official names of this protein?
TWiK family of potassium channels protein 12.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RNH2_FRAP2
Sequence: MIILGIDEAGRGPLSGPVVAAGVILDPEKTIDGLADSKKLTEKKRQSLYEVITAHAKAYTIVEVSPQQIDQLNILQATLKAMNQVADNLKGQFDKVLVDGNKLPNWDYNSEAIVKGDSKVQEISAASILAKVHRDNICLEHDRLFPQYGFAKHKGYPTKEHLENIRKYGVLNIHRKSYKPIQLLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_PORGI
Sequence: MKKPFRIGFGFDVHRLSEGYPLWMGGVRLEHSKGLEGHSDADVLIHAICDALLGAAALRDIGYHFPPSDPQYKGIDSKILLARVMELVRSQGYELGNIDATIAAEQPKLNPHIPDMQRVLAEVIQVEVSDISLKATTTEKLGFTGREEGISAYAVALLIAAV
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: Y3648_BRUA2
Sequence: MNARLTGLGLNLLSFAVGIGGWYLLTATGAVVLPGPVDVLERAVTLLLNGQLVGDIFASLRRVLSGFVLGVALAIPVGFLMGWYRIARSLIEPWVQFFRMIPPLAVIPLAIVTLGIDESPKIFVIFLASFLSSVVATYQGVISVDRTLINAARVLGAKDATIFARVIVPASVPFILVGVRIGLGSAWATVVAAELIAAQSGLGYRMQQAQLYYDLPTIFVSLVTIGILGLFMDRLLQAADRRLTQWQERA
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Probable ABC transporter permease protein BAB2_1148.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HCP_SHEPA
Sequence: MFCIQCEQTIRTPAGNGCSYTQGMCGKSSDTSDLQDLLIYILQGVSSYAALAREVGIIDHEIDTFVPKAFFATLTNVNFDDERIIAYTTQAETFRNRLKAAYEAKCSELNIDAKPMNAPMQLVLGASKPEMLSQALQAVPNRGKDEVHEDIMGLRLLCLYGLKGAAAYMEHARVLDQTSDEVAGEFHEIMAFLGEDSVDADKLFNTAMQIGQLNYRVMAMLDEGETHAFGHPEPTQVNTKSVKGKAILVSGHDMKDLELILEQTQGKGINVYTHGEMLPALAYPELKKYPHLVGNYGSAWQNQQKEFATFPGAVVMTSNCIIDPNVGDYSNRIFTRSIVGWPGVTHIIGDDFSEVIAKAESLEGFIYDEIPHLITIGFARNALMAAAPTVIENVKSGAIKHFFLVGGCDGDKQERGYFTDIATQAPADSVILTLGCGKYKFNKLEFGDINGIPRLLDIGQCNDAYSAIQLAIALSEAFECDINELPLTLVLSWFEQKAIVVLLTLLSLGVKNIMTGPTAPAFLTPNLAKVLEEKFGLRNTTTVEADLNRVLNVA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BVMO2_STRCO
Sequence: MAEHEQVHEHVRVAVIGSGFGGLGAAVRLRREGITDFVVLERAGSVGGTWRDNSYPGCACDVPSHLYSFSFAPNPEWPRTFSGQEHIRAYLEHVADTFGLRPHLRFDSEVKRMAWDTEQLRWEIETVRGTLTADVVVSATGPLSDPKVPDIPGLDTFPGKVFHSARWDHDYDLAGQRVAMIGTGASAIQIVPSIQPKVDRLTLFQRTPAWVMPRVDRAISGAERALHRALPATTKLRRGLLWGIRELQVQAFTKHPNELGFVEQIAKRNMGAAIKDPALRAKLTPDYRIGCKRILLSSTYYPALAKPNVDVVASGLSEVRGSTLVAADGTEAEADAIVFGTGFHVTDMPIAERVVGADGRTLAETWKGGMEALRGGTAAGFPNFMTVIGPNTGLGNSSMILMIESQLNYLADYLRQLNVLGGRTALDPRPAAVRNWNHRVQERMKRTVWNTGGCTSWYLDASGRNTTVWPGTTAEFRRETRRVDLAEYQVLRPAPAQVGAKAAEADTGADTGADAEVSA
What is the function of this protein?
Catalyzes a Baeyer-Villiger oxidation reaction, i. e.  the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor.  Thus, can convert bicyclo[3. 2. 0]hept-2-en-6-one into the oxidative lactone products 2-oxabicyclo[3. 3. 0]oct-6-en-3-one and 3-oxabicyclo[3. 3. 0]oct-6-en-2-one.  Is also able to catalyze the sulfoxidation of methyl phenyl sulfide (thioanisole).
What are the official names of this protein?
Baeyer-Villiger monooxygenase, BVMO.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: SYS_LEGPC
Sequence: MLDNQLLRENPQYVATQLLKRGFQFDAVTFSQLEEKRKALQVSTQSLQNERNLRSKAIGEAKSRGENIEPMREEVNKLGAKLEQQKTELDEVLKQIEVISLSLPNIPHESVPVGKDELDNQEIRKWGDVPAFSFPVKSHDELGEALGQMDFALAAKITGSRFVVMKGHLARLHRALIQFMLDIHIQQHGYQEIYVPYIVNADSLLGTGQLPKFEADLFKLTGDNGYYLTSTSEIPVTNTVREMILSAEQLPIRYVCHSPCFRSEAGSYGKDTKGMIRQHQFEKVELVWITKPEDSYNALEQLTQHAEVILQRLNLPYRVVALCTGDIGAGSAKTYDLEVWLPSQNTYREISSCSNMEAFQARRMKARFRNPDTNEIQLVHTLNGSGLAVGRTLVAIMENYQDEHGNIHIPDALKPYLGGIDIISVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SALAI
Sequence: MTAVSLGMPAVPPPPLASRRASRQIMVGPVPVGGGAPVSVQSMTTTLTADVNATLQQIAELTAAGCQIVRVAVPSQDDVEALPAIARKSQLPVIADIHFQPRYVFAAIEAGCAAVRVNPGNIRQFDDKVKEIAKAAGDAGVPIRIGVNAGSLDKRLLAKHGKATAEALVESALWECSLFEEHGFRDIKISVKHNDPVVMVRAYRQLAEACDYPLHLGVTEAGPAFQGTVKSAVAFGALLAEGIGDTIRVSLSAPPVEEIKVGTAILESLGLRERGLEIVSCPSCGRAQVDVYKLAEEVTAGLEGLPVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPEGQIVETLIEEALRLADEMGAELPDELRSLVGGATVTVH
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: DBH_CHLPN
Sequence: MATMTKKKLISTISQDHKIHPNHVRTVIQNFLDKMTDALVKGDRLEFRDFGVLQVVERKPKVGRNPKNAAVPIHIPARRAVKFTPGKRMKRLIETPNKHS
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
Probable DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: LICI2_TACTR
Sequence: MLSRRTLDCCLVMLIVSTTFCQELHFYKEKADRSHENLKTAVNQFGIHLCRRLLNEGKNIIFSPFSLSTALSMAFVGARGNTAIEMRSGLGFREAGLAQEDVPDSFYQAFQLLKSDQSGDKFYVANTALVQNNYNILNSYKRILHRKFYSDIQPVDFVRNGLWVKEMVNKWVSNITHNKITSLIDKPLSPLTRLFLLNAVYFKGSWKTQFDRKRTTLSLFYNNNKVARRVEMMSLTNKFPYTYDSELKCQVLELPYDGDKTSMIFILPEWDVRLKHVENALSAQSVKQLINNLQDTEIVVTIPKFKLENSPQIKEYLQVMGMNEAFSFSADFSGMNGRRNLFVKDVLHKAMIDVNEEGSEAAAVSGVVVMLKSASHNLPTFVANHPFMFLIINKESGMILFLGSVREL
What is the function of this protein?
Serine protease inhibitor that inhibits proclotting enzyme and to a lesser extent clotting factor C and clotting factor G.
What are the official names of this protein?
Intracellular coagulation inhibitor 2, Limulus intracellular coagulation inhibitor 2, LICI-2.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted. Note=Localizes in the large granules of hemocytes (PubMed:7822280). Secreted in hemolymph in response to external stimuli (PubMed:7822280).
Protein: FRIL2_MOUSE
Sequence: MTSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKREGAERLLKLQNERGGRALFQDVQKPSQDEWGKTLEAIQAALRLEKNLNQALLDLHALGSARTDPHLCDFLESHFLDKEVKLIKKMGNHLTNLRRVAGPQPVQTGVAQASLGEYLFERLTLKHD
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney.
What are the official names of this protein?
Ferritin light chain 2, Ferritin L subunit 2, Ferritin subunit LG.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: NEP_I63A1
Sequence: MDSNTITSFQDILQRMSKMQLESSSVDLNGMITQFERLKIYRDSLGESVMRMGDLHSLQSRNATWREELSQKFEEIRWLIAECRNILTKTENSFEQITFLQALQLLLEVESEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: NS6_BCHK3
Sequence: MFHLVDFQVTIAEILIIIMKTFRVAIWNLDILISSIVRQLFKPLTKKNYSELDDEEPMELDYP
What is the function of this protein?
Could be a determinant of virus virulence.  Seems to stimulate cellular DNA synthesis in vitro (By similarity).
What are the official names of this protein?
ORF6 protein, ORF6, Accessory protein 6, Non-structural protein 6, ns6.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses accessory protein 6 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane. Host Golgi apparatus membrane.
Protein: YL686_MIMIV
Sequence: MNPTSVEVSTTNIEVNQKSQCTVDAPSDCQCNLTSETVIDVNDKIDVVVVDTSDNIPKPQITEKVVEKEVVEQVKKTSTIKVRLEAKTKLNYINQFLDQAPKESVVLHKGLDVELVSGITISIGDNRENKYTVVSDWLPVPVHATNINTPNPNNLTSVNCVLPSETVVLTDRGLPWKLPVDFSVELPNPCPVTIYAGTKLQQNEFQVVLASDCKVNVVY
What are the official names of this protein?
Uncharacterized protein L686.
Protein: YCJF_SHIFL
Sequence: MTEPLKPRIDFDGPLEVEQNPKFRAQQTFDENQAQNFAPATLDEAQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGIQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTVRLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EXLYS_BPKMV
Sequence: MAESQRASQELGINVGQTQLQPGQSARRGVRDSEVNYSGPSVGSQILDGILGAGQQIAGKWFEHNVQQEVLRGERARMAGEAEEAVDSNVLAKPFVKGGWRKQDYRIAQADFSLKMQRFIANKGREMTPEEFRKYLSQEATHVLDSTEGMNPNDALQALAQQQKAEEQLFGMQAKAYMDWSIDQAARGFRTQGNSILAKAVQAQATGDELSRQLSLEEAGLFYTNIMTSEDIPLEVRDKVGMQFLAASLDMNQRGIYEGLRDAGFLDSMSFDDRRALNGLYEKSKAQTRAKESMATLRADADFQQRVANGAITDLAEVEAYSRGMVEEGRWSDAQAISFMTKAMTGLGNAQRMQGIMAALEAGDINALHTLGTNVTEALEQWDKMQAANGSSLTDRLVQGTQLGLRLGTFPKTYGESVGSAVRMIQAAKEGEANPELVNTLNSIFEQVASAQEINPSAGNVMLSGIPEAEQGAVAWALKQMKMGIAPAQALREFSANAEVVKQMDEFEKGQNTKAFKDNLGKQVNDKFVNNIFGRAWNMLTGESDLSNNEAVLSMYRRATIDEANWLASDRKHAGLLTSDTGREALLEIAAANVRNRTIQVGEGRNLKEGDLFSRRDSAPLILPRGTTAEQLFGTNDTETIGTVLAEQHKPHVEGLLGYKSVVAFEYDRTSGSLLAVEYDENGVALDRTRVDPQAVGKEVLKRNADKLNAMRGAEYGANVKVSGTDIRMNGGNSAGMLKQDVFNWRKELAQFEAYRGEAYKDADGYSVGLGHYLGSGNAGAGTTVTPEQAAQWFAEDTDRALDQGVRLADELGVTNNASILGLAGMAFQMGEGRARQFRNTFQAIKDRNKEAFEAGVRNSKWYTQTPDRAEAFIKRMAPHFDTPSQIGVDWYSAATAE
What is the function of this protein?
Component of the cylindrical core that assembles on the inner surface of the capsid during procapsid formation.  Plays a role in ejection of the bacteriophage DNA into the host cell at the initiation of infection.  Functions as an exolysin that catalyzes the cleavage of the host peptidoglycans.
What are the official names of this protein?
Peptidoglycan hydrolase gp36, Gene product 36, Gp36.
What are the subcellular locations of this protein?
Virion.