PharMolix/UniProtQA huggingface dataset:
Protein: GRPE_PICTO
Sequence: MMTYNKKYIDSVEYDLIETRKRMWMMERKKNEELLKKYQQAMSDLEDYKNLYMRQRSEMENYQRYIEKTINNIKANANADLIKTMLPVLDSLDAGILHDEKLKPIRSQLIKILSNYGLKEIESRGKKFDPYLNEVVGIVKGDDDIVVEEVQKGYILNNEVLRTSKVIVSKGGNNEQDNRN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_HALOH
Sequence: MNNFMKNIGFYLVLIALSILVAQFFVDTDVNTIVDTDVNTIKDFTYSDLINYVEQGKINEVTIIGNEAVKGTYNHREFNVPIPPEAVPDLMAELREADVEIKTEPEPTAPWWTGMLAYILPIILLIGAWFFIMQRMQGGGSQMMSFGKSRARLSENGKKVTFEDVANYEEVKEELQEVVEFLKNPDKFTRMGAKVPKGVLLVGPPGTGKTLLARAVAGEAGVPFFIISGSDFVEMFVGVGASRVRDLFEQGKKNAPCIIFIDELDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFEPNEGIIVMAATNRPDVLDPALLRPGRFDRQVVVDKPDVKGRMGILKIHLRNKPVADDVDVEVLAKRTPGFTGADMENLANEAAILAVRRRKNKITMEDFDDAIDKVIAGPAKKSKVMSERERKLVAYHETGHALVGDLLEHADRTHKISIVPRGRAGGMRWALPKEDKNFMSKQELLDQITVLLGGRASESIFLEDISTGAQNDLERATKLARAMVTEYGMSEKLGPLTLGHKHDEQIFLGRDISRQRNYSEEIAAEIDKEVSSIIEYCYQRAEKILQENTAKVERIVRELLDRETLDAEQLQKLIKGEPLDDDSIDNSTDENENREHENNDK
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: ATP6_ECO45
Sequence: MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLYC_HRSV8
Sequence: MSKHKNQRTASTLEKTWDTLNHLIVISSCLYRLNLKSIAQIALSVLAMIISTSLIIAAIIFIISANHKVTLTTVTVQTIKNHTGKNISTYLTQVPPERVNSSKQPTTTSPIHTNSATISPNTKSETHHTTAQTKGRITTSTQTNKPSTKSRSKNPPKKPKDDYHFEVFNFVPCSICGNNQLCKSICKTIPSNKPKKKPTIKPTNKPTTKTTNKRDPKTPAKMPKKEIITNPTKKPTLKTTERDTSTSQSTVIDTITPKYTIQQQSLHSTTSENTPSSTQIPTASEPSTSNPT
What is the function of this protein?
Helps the virus escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fc-gamma receptors.
What are the official names of this protein?
Major surface glycoprotein G, Attachment glycoprotein G.
What is the protein family that this protein belongs to?
Belongs to the pneumoviruses glycoprotein G family.
What are the subcellular locations of this protein?
[Isoform Membrane-bound glycoprotein G]: Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform Secreted glycoprotein G]: Secreted. Note=The protein is shed from infected cells before the appearance of progeny virus. The initiation at the downstream methionine removes a portion of the transmembrane domain. The remaining hydrophobic portion of the sG protein is essential for translocating it into the lumen of the ER during translation and would likely maintain its membrane association until a proteolytic event releases the mature sG protein into the medium.
Protein: DTDA_METMA
Sequence: MTDIIPENVNNSKITIICSAPDLASQNIKNHLLNLTEWKNLELPPESRFSAARESIDGKFRLVDIEEIHVFQDGLDRKLEAAGLPASLIIFASKHRSKEEINSLTVHCTGNPSGEARLGGHPKELAVSSPAAMKSILSGMKKLAGEKELKYDVTLEVTHHGPTELSVPSIYAEIGSTEKQWEDPDAGEVAAKSILAVSLEKVPVAVGFGGGHYAMRQTGLLLETKISFGHNFPKYQLEFVDEALVRQAVEKSGAEFAYFDRKSMKSEDRKKISEILEKLGLRVLKESEIRENYGLDD
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: Y1056_DESVH
Sequence: MTDTTGNPLLSLDDIHFTYPGTTAPVLRGATLHLAQGDRLGLLGHNGSGKTTLLHIAMGLLRPESGTVHHRNAVAHDEASLAALRRDIGFLFQNADDQLFCPTVLEDVAFGPLNLGLSPEQARERATQTLQGLGLEGFGARVTHRLSGGEKKMVALASVLSMQPTALLLDEPTNDLDPATRQRLIDVLNRMSATHIIISHDWDFLARTCTTFLTVDDGIVCTSRHTPHVHTHIHHGGEVAHEHPSRGCCHQHDGSHHHAGHDDDHPHTSQTTE
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein DVU_1056.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1959_STRT1
Sequence: MGFTDETVRFNLNDGDKDEISNTLTNVYRSLAEKGYNPINQIVGYVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLKGNGTDL
What are the official names of this protein?
UPF0297 protein str1959.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: KDPA_THEVO
Sequence: MIFPAEDVYFWSKFFATERAVSGVIIIFIYLGITSIFSYVLSFYIAKIYRDEPTFLRKLTGSVISFFEKIIGESENHQMEFKEYFINLLLFNFFAGLISFLVIMYQKYLPFSYYATGMSPSLDFNTVVSFLTNTNLQHYSNPFRLSYFSQTFVITGLMFLSAGTGFAASMAFVRGLRTDVGKIGNFYHDFLVSIFDLILPLSILVTIILILAGVPETIQRFISVTPFFTNNTVNIPLGPVATLEAIKNIGTNGGGFYGANAGFPFENPDWFTNLLEFVSFTIIPLGSLMALGIVFEDRKFGRMLYYVIMFFFVFDGLFAFFGEYVGVPFLHIGYYTGNMLGKETAIGVSQSSIFAVGATLTSTGASDGALVSYTPAGIIGVLIGLLLNDPLGGVGTGVLNIFMYIIFTVFIGSLMVGKLPELMSLRIGSKEIKYSTLSLVTHPLLVVIPLGITLMIPHLSSTFVNPNSSRITELLYEFASAASNNGSEMGGFLTNQPYFNYLDGVIMLLGRYLLMGFQLVIAQSFSIKKAKVQYLRSIDTSNSVFALLLISAMLIIGLLSYFPIIVLGPLLSWTHDFSLIVGAIL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VG69_BPML5
Sequence: MTDTKTLLPLRSVSQLNQYTRCPQAYKLARIDKVWARPAAWLPQGTAFHTVAEVYEKALAEGREMSLERAQEIFREEYAKDIGALCDETPNFEWWFWSGPYNGERDIERRFHLGLEQVEKFIAWRKDKGQQIWTTPGRGICSTEAWKDTNCKECEQPKPAIELPFNIELDGIRVRGFIDAVVVVNGELRVRDYKTGNSPGDDFQLGVYALAVAMTYDVEAPKTGDYFMAGKKGIKAKPTAPYDLTDWTRERITERFHEVEARIQAGDFEPLPEPDKCGFCDVNYSCPVFK
What are the official names of this protein?
Gene 69 protein, Gp69.
Protein: YN87_YEAST
Sequence: MSSTDIKPCAVNIPVSAHITFHYKSIADRSSSRSSSSSSCSSATSKACSPRGSSVGLPPALSTDNEIVETVLNVSAPVVADPTRPSLFKSNYTAASCLTSDPTSPSLLPSSRRNSVLPASDFHQCAHHKNFQRRASEPQLPSFDNRSSSEMKRSVSYAQHSMMFPISDQQEPQTSASPNDHSDPSCPCNRHHHRRNSVAVKFDKPLYERLET
What are the official names of this protein?
Uncharacterized protein YNR014W.
Protein: MDH_ECO57
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: MALK_SHISS
Sequence: MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQVGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDVVLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Maltose/maltodextrin import ATP-binding protein MalK.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KAD6_PLAF7
Sequence: MKRKVPNIIITGVPGSGKSTLCEELKEIINKELLKRNDMEGFEMTHLNLSNIIKDERLYKEFDDELDASIYSEELLNEYLKKKYKLEKGGYIIDFHDINFVKDVDIIDKIFLLTIQTNFLYERLEKRNYTKEKIKNNIECEIFQVIKEDILDHFPNTNILQEIENNDLQQYDNNLSIIKNWVLSYI
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  Has also ATPase activity.
What are the official names of this protein?
Adenylate kinase isoenzyme 6 homolog, AK6, Dual activity adenylate kinase/ATPase, AK/ATPase, PfAKLP1.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCPR2_ORYSJ
Sequence: MESSAGPMELVAALLRGLTPRAEQLLQLSSGGGEAAAGGAAEARAAVATVAAALLGCAFLVLWRRVSAGRKRKREEAERSAAAVAGVGKGGKNASAAAGEEAGGADGRKRVTVFFGTQTGTAEGFAKALAEEAKSRYDKAIFKVVDLDEYAMEDEEYEERLKKEKISLFFVATYGDGEPTDNAARFYKWFTEGNERGVWLNDFQYAIFGLGNRQYEHFNKVAKVVDELLVEQGGKRLVPVGLGDDDQCIEDDFNAWKETLWPELDQLLRDENDVSTGTTYTAAIPEYRVEFVKPDEAAHLERNFSLANGYAVHDAQHPCRANVAVRRELHTPASDRSCTHLEFDIAGTGLTYETGDHVGVYTENCLEVVEEAERLLGYSPEAFFTIHADKEDGTPLGGGSLAPPFPSPITVRNALARYADLLNSPKKSALVALATYASDSTEADRLRFLASPAGKDEYAQWVVASQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRYYSISSSPSMAPTRIHVTCALVHEKTPAGRVHKGVCSTWIKNAIPSEETKDCSWAPVFVRQSNFKLPADPSVPVIMIGPGTGLAPFRGFLQERLSQKQSGAELGRSVFFFGCRNSKMDFIYEDELNTFLEEGALSELVLAFSREGPTKEYVQHKMSQKASEIWDMISQGGYIYVCGDAKGMARDVHRVLHTIVQEQGSLDSSKAESFVKSLQTEGRYLRDVW
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes (By similarity) (PubMed:23053415).  It can also provide electron transfer to heme oxygenase and cytochrome B5 (By similarity).  Can reduce cytochrome c in vitro (PubMed:23053415).
What are the official names of this protein?
NADPH--cytochrome P450 reductase 2, CPR, OsCPR2, P450R.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the flavodoxin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single- pass membrane protein; Cytoplasmic side.
Protein: ACPS_STRT2
Sequence: MIFGHGIDLQEISAVKKAYDRNPRFAKKVLTPKEWERFESLSGERQMSFLAGRWAGKEAFSKAWGTGIGAVGFKDIEILNNDKGAPVVTQSPFEGNVFISISHSGDFVQASVILEKTKR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_AERS4
Sequence: MSRVAKAPVTIPAGVEVTLNGQELSIKGGKGSLVRSIHAGVEVTKEDNVLKFAPRDGIAGADAQAGTARALANNMVIGVTQGFERKLQLVGVGYKASIKGNAVALALGFSHPVEHALPAGVTAECPTATEIVLRGVDKQLVGQVAADIRSYRAPEPYKGKGVRYANEQVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ALPK2_HUMAN
Sequence: MKDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLDISVSSSENPLGVKGTRHTGEAYDPSNTEEIANGLLFLNSSHIYEKQDRCCHKTVHSMASKFTDGDLNNDGPHDEGLRSSQQNPKVQKYISFSLPLSEATAHIYPGDSAVANKQPSPQLSSEDSDSDYELCPEITLTYTEEFSDDDLEYLECSDVMTDYSNAVWQRNLLGTEHVFLLESDDEEMEFGEHCLGGCEHFLSGMGCGSRVSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKHGPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFASDNLLNMDESVRETEMKLLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQPGMKGNPKKPNANLRESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPAKYLAVSIPEDKHAGGTEERFPRASHEKVSQFPSQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLPEGEGFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQSLSQQGSLSAPDFQQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWGTRVSVVAETAGEEDSQALSNVPSLSDILLEESKEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESKASDGGLIIPDKVWAVPDSLKADAVVPELAPSEIAALAHSPEDAESALADSRESHKGEEPTISVHWRSLSSRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQLKMDHTAFFKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREGGQSNDGNMGHEAEIQPAILQVPCLQGTILSENRISRSQEGSMKQEAEQIQPEEAKTAIWQVLQPSEGGERIPSGCSIGQIQESSDGSLGEAEQSKKDKAELISPTSPLSSCLPIMTHASLGVDTHNSTGQIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPSSPDLTRFPCTSSPEGNVTDFLISHKMEEPKIEVLQIGETKPPSSSSSSAKTLAFISGERELEKAPKLLQDPCQKGTLGCAKKSREREKSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLAEGVKKKILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKAGPETPGEKKT
What is the function of this protein?
Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370).  Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752).
What are the official names of this protein?
Alpha-protein kinase 2, Heart alpha-protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane.
Protein: PG077_VACCT
Sequence: MAEFEDQLVFNSISARALKAYFTAKINEMVDELVTRKCPQKKKSQAKKPEVRIPVDLVKSSFVKKFGLCNYGGILISLINSLVENNFFTKDGKLDDTGKKELVLTDVEKRILNTIDKSSPLYIDISDVKVLAARLKRSATQFNFNGHTYHLENDKIEDLINQLVKDESIQLDEKSSIKDSMYVIPDELIDVLKTRLFRSPQVKDNIISRTRLYDYFTRVTKRDESSIYVILKDPRIASILSLETVKMGAFMYTKHSMLTNAISSRVDRYSKKFQESFYEDIAEFVKENERVNVSRVVECLTVPNITISSNAE
What is the function of this protein?
DNA-binding protein which binds to the hairpin form of the viral telomeric sequence.  Required for the production of mature virions (MV).
What are the official names of this protein?
Telomere-binding protein OPG077, Telomere-binding protein I1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG077 family.
Protein: GLGC_RHOJR
Sequence: MRSQPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVNAGYLRLCVLTQYKSHSLDRHISQTWRLSGFAGEYITPVPAQQRLGPRWYTGSADAILQSLNLVYDEDPEYIVVFGADHVYRMDPEQMVQHHIESGAGVTVAGIRVPRSEAFAFGCIDSDESGRIVQFLEKPAHPPGTPDDPNMTFASMGNYVFTTKVLVDAIRADSENSDSDHDMGGDIIPALVEAGEASVYDFKDNIVPGATDRDRGYWRDVGTLDAFYDAHMDLVSVHPIFNLYNRRWPIRGETENLAPAKFVQGGLAQESVVGAGCILSAATVRNSVLSSNVMVDSGATVEGSVLMPGVRIGKGAVVRRAILDKNVVVGDGEIIGVDLERDKQRFAVSNGGVVAIGKGVWI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: MNME_STRTD
Sequence: MSITKEFDTITAISTPLGEGAIGIVRLSGTDAIAIANKVFKGKNLETVDSHTINYGHIVENNEIIDEVMVSVMRAPKTFTREDVVEINTHGGVAVTNEILQLLIRSGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMTVAVSQLDGSLKNLINNTRQEILNTLAQVEVNIDYPEYDDVEEVTTNLVREKTQEFQALLENLLATAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREEKAIVTDIEGTTRDVIEEYVNIKGVPLKLIDTAGIRDTDDVVEKIGVERSKKALEEADLVLLVLNSSEPLTDQDRTLLDISQNSNRIILLNKTDLPQAIQTEELPEDLIPISVLKNENIDKIEDRINQLFFDNAGLVEKDATYLSNARHISLIEKALESLEAVNQGLELGMPVDLLQVDMTRTWEILGEITGDAAPDELITQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_CHLCV
Sequence: MNLKELLNNIEAKIYGKVSPIEVRNLTKDSRNVGFGDIFIANKGKQFDGNDFSPLAIENGAIAIASSIYNPFLSVVQIVSSNLPQLEAELSAKYYNYPSKKLCIVGVTGTNGKTTVSHLIKTLFDGCNKPSGLIGTIEHVLGNNRIQDGYTTPESCLLQKYLAEMVKNRLTSAVMEVSSVGLVLERLAEVDFDVGVLTNITLDHLDFHGSFEEYINAKLKLFSKLPATGLAVVNGDLSYASRFLEMTQAQPITYGIECPADYRAMHLRSSPFGTDFDLVYRGESLPCRLPLIGKHNVYNILAAIAVAHQHCNGDLQQLISLAANVESPRGRLEPVFSGPCPIYIDYAHTPDALENVCKTLHALLPEQGKLIVVFGCGGDRDQSKRQIMAEVVERYGFAVVTSDNPRGEDPEEIIKAICSGFVKRNFSIEIDRKQAITYALSIASDRDIVLVAGKGHETYQIFKHQTIAFDDKEIVREVLSSHV
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLR_KLEPN
Sequence: MTEVRRRGRPGQQEPSAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLEGADFVYQDSQLGWWHIGLGAFNIGSAYIHNRDVLSVGGPFMRRLMLMSGETVNVAIRNGNEAVLIGQQECKSMVRMCAPLGSRLPLHASGAGKALLYPLPAEELVDVIVKTGLQRFTPTTIVDLPVLQRNLDEARACGYSIDQEEHVTGLNCIASAVYDDVGSVVAAISISGPASRLTPDRFVSQGELVRETARNISTALGLKPQAD
What is the function of this protein?
Negative regulator of allantoin and glyoxylate utilization operons.  Binds to the gcl promoter and to the allS-allA intergenic region (By similarity).
What are the official names of this protein?
HTH-type transcriptional repressor AllR, Negative regulator of allantoin and glyoxylate utilization operons.
Protein: DABA_GEOSW
Sequence: MNTTTVSLERPNVHERRRENVATDINVNALVKNASKAIAPLWPIATFVARHPWMGLEHFSFEQVVHRLKLLRDIDLYPSMAMFRAAQRKGELNPKFLEMRLQRWLDEQPLTMPREEAERFCRAALLHEEIPNELLTSSSLKSLAAKMKDMRLRYDSNHLLTRPLSLLLEEQGKEKWARVLDHQMIKWCKLFLDESQALWAMPYREKGFYYAWRKLVINDPSLNKQQRERLKDLPHDPEEALRQALMLLGIPHGEMKGYLEAHLLSLPGWAGMLLWRSQQSGQAHLLLVDYLAIRLSLEWALIAPHLPFAKQKDDDEAFLLPLLAAWMHWGGWTPEKWLQLPQAEQQARLSFAYRFDKIVRGKLWLEAWEDTQEAQLKKRIASHSQNNEPKQAVAQLIFCMDVRSEPFRRHLEQAGPFETYGCAGFFGLPIKTRELDSSHAHASCPVIVEPRHEVQEFTSAENVKKYRGRRNALLSVSHTFKKMKQHLFASLLLPEVSGPLLGLHTLARSIAPSGAGRVFHQFQDNWAQKPATELSLNRESSLETTETTDLPVGFSTEEKVRYVYQLFKGMGLTSRFAPLVVVCGHESTTTNNPYASSLDCGACGGAAGGFNARVFAALCNLKEVREGLAKEGIVIPEDTVFVAAEHMTTVDDLCWLYVPTLSEAAQKAFDMLQGKLEEVSRNANNERLSKLPGLEGKKKDPLAEAHRRAEDWSEIRPEWGLAGNAALIIGRRELTKHCNLEGRVFLHSYDWRKDPSGEALANIITGPVTVAQWINLQYYASTVAPHYYGSGNKTTQTVTAGIGVMQGNASDLLAGLPWQSVMASDEEIFHSPLRLLVIIEAPQQNIERLFEDDPHFRRKVKNGWLRLVSIDPDSGEWKAWR
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL20_STRP8
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVADAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: SLM6_YEAST
Sequence: MCSRFSSTSLKCLLCSQNRHCSSGISTLLRSFSCITLSAISSSVNCSGSSFLGSSFSLFSSFSCKESLLRSGVFPSWLFCMFSSILALAISNSFFFFSSNACFSLLFNSFLVTGFSFSADLLVLAAAADTLESNVSNDIGGNCATRLFKL
What are the official names of this protein?
Protein SLM6, Synthetic lethal with MSS4 protein 6.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LUXS_THET2
Sequence: MAEVESFSLDHTKVKAPYVRLAGRKALAGGVVEKYDLRLAQPNREALPTGALHTLEHLLAGYLRDHLPGVIDLSPMGCRTGFYLVVEGPVGEEKVLEAFAQALKDVLAHEGEVPGASFRECGNYRDHDLPGAKAWAEKVLKAGLRVQATVPLEAR
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.