PharMolix/UniProtQA huggingface dataset:
Protein: I17RD_MOUSE
Sequence: MAPWLQLCSFFFTVNACLNGSQLAVAAGGSGRARGADTCGWRGVGPASRNSGLHNITFRYDNCTTYLNPGGKHAIADAQNITISQYACHDQVAVTILWSPGALGIEFLKGFRVILEELKSEGRQCQQLILKDPKQLNSSFRRTGMESQPFLNMKFETDYFVKIVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMHVSFDHAPQNFGFRGFHVLYKLKHEGPFRRRTCRQDQNTETTSCLLQNVSPGDYIIELVDDSNTTRKAAQYVVKSVQSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESPESSTYAAALPRDRLRPQPKVFLCYSNKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWAIQKIHESQFIIVVCSKGMKYFVDKKNFRHKGGSRGEAQGEFFLVAVAAIAEKLRQAKQSSSAALRKFIAVYFDYSCEGDVPCSLDLSTKYKLMDHLPELCAHLHSGEQEVLGQHPGHSSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFIPFQHPPVRYQEPVLEKFDSGLVLNDVISKPGPESDFCRKVEACVLGAAGPADSYSYLESQHVGLDQDTEAQPSCDSAPALQPLLHAVKAGSPSEMPRDSGIYDSSVPSSELSLPLMEGLSPDQIETSSLTESVSSSSGLGEEDPPTLPSKLLASGVSREHGCHSHTDELQALAPL
What is the function of this protein?
Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation (PubMed:12604616).  Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK (By similarity).  Mediates JNK activation and may be involved in apoptosis (PubMed:15277532).  May inhibit FGF-induced FGFR1 tyrosine phosphorylation (PubMed:12604616).  Might have a role in the early stages of fate specification of GnRH-secreting neurons (PubMed:23643382).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (PubMed:25576668).
What are the official names of this protein?
Interleukin-17 receptor D, IL-17 receptor D, IL-17RD, Interleukin-17 receptor-like protein, Sef homolog, mSef.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Associated with the Golgi apparatus and is partially translocated to the plasma membrane upon stimulation.
Protein: WBP2L_BOVIN
Sequence: MAVNQSHTESRRGALIPSGESVLKQCEDVDLCFLQKPVESYLFNGTKKGTLFLTSYRVVFVTSHLVNDPMLSFMMPFGLMSDCTIEQPIFAPNYIKGTIQAAPGGGWEGQAVFKLSFRKGGAIEFAQLMVKAASAAARGIPLGSVNYWFDTSGLYIITVPGAAVCSSQTPCPAYPIVIYGPPPPGYTVQPGEYGTPPEGYGAQPGGYGAPPMGYGAPPVGYGVPPGGYGVPPGGYGVPPGGYGAPPGGYGVPPGGYGAPPGGYGAPPAGYGAPPAGNEALPPAYEAPSAGNTAASHRSMTAQQETSLPTTSSS
What is the function of this protein?
May play a role in meiotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization.
What are the official names of this protein?
Postacrosomal sheath WW domain-binding protein, WW domain-binding protein 2-like.
Protein: ACPS_CHLTE
Sequence: MEIGVDIVEIARIRSSYDRFGEAFMKKILTSAEMAQCLSKPDPVASLAGRFAAKEAVSKALGTGIAKGLTWHSIEVLNDETGKPCVSVYAPSFSGRVSISISHDRYSAVAMALFEPR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2868_RHOCS
Sequence: MTGQPLTMETAAGADAGTGAATHPADGRRPVVVVTGMSGGGLSTALKALEDLGYEAVDNLRLSLLTALVFQAHDRPLAIGIDSRTRDFSADALLQELDALRAHPDLRVRLLFMEATEEVLQRRYTETRRPHPLAVDRPVPDGIALERTLLVPLREAAEVVIDTSQLSIHDVRRLLTGHFRLDGDPSLHVFVTSFAYRHGVPREADLVFDVRFLDNPHWDPALRPLTGLDRPVAEHVGRDPDFPDFFRHLTTLLAPLLPRYAREGKHYLTIAIGCTGGRHRSVFTAHRLAGWLRDQGYKVGEGHRDLDRRHPAPEPAPPWREVASRETPEEHR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein RC1_2868.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: MSRQ_PSEPK
Sequence: MRYPWFRLAIFIVGCLFPVWWLYEAAMNLLGPDPGKIMMDRLGLGALTFLLVTLSMTPLQKLTGWSGWIVVRRQLGLWVFAYIVLHILCYLFFILGLDWGQLAVELRKRPYIIVGALGFLGLLVLAVTSNRYSQRRLGARWKKLHRLVYAVLGLGLLHFLWIVRSDLREWAIYAFIGAVLMVLRIPAVARALPKVAR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: POF11_SCHPO
Sequence: MNQDDNGKNVVSKVSDLTSCSDFSTSSPVPCLNPLSHENNRIDLIRDLLASLSKEGVVAVYNHVRSLLFTDFTEVFPEEVSLRVFSYLDQLDLCKCKLMSKRWKRLLEDPGIWKALYMQKGWFVNENVLNEFEAWRRTHKFPQPRFENFLKQQNIIGPYGTMFLPQQFIFDSNGRPLLNWSYLYKEHAHLDSNWRHGRFLVSTFNNPSIRFPADQDFRATLDSVYCVQYDDEIMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWDWQNRRPLKVYFGHTDNVLGVVVSENYIISSSRDHTARVWRLDATSPAEACMHVLRGHLASVNSVQYSSKTGLIVTASSDRTLRTWDITTGHCIRIIHAHQRGIACAQYNGKFIVSGSSDLTIRIFEASSGKLLRMLQGHEDLIRTVRFNDEKIVSGGYDGTVRIWNFNTGEQHCVLHNSRNSRVFGLQFDHRRIIACTHSSEILVWNFDDGLDCTFF
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
F-box/WD repeat-containing protein pof11, Meiotically up-regulated gene 156 protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXAC_SALPC
Sequence: MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHRQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDHGIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: LYSZ_SULTO
Sequence: MIVIKAGGRVIKNNLDGIIESLSNVGEQAIFVHGGGDQVTETSKKLGIEPVFVTSPEGIRSRYTSKEELEVFIMVMSLISRQIVSKLAYKKKVISLTGADGNSVIAERKKKIIIIDERGRKRIVDGGYTGKIKKVDSLVISDLLKSFDLLVFAPLAYDPEEKTLLNVDGDQMAFAIATAMKADTLILLTDVEGVLVDGKVINKLTSKEAKELSKRIGPGMNRKLLMAGETIENGVKKVIISSGLVQDPISNALQLRGTVIM
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.  Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
What are the official names of this protein?
[LysW]-aminoadipate/[LysW]-glutamate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. LysZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YME1_ACIFR
Sequence: MGVAMIDALNIATMPIADKVHRHMLASYYALQLDALQAEAKRLGYFFAQADTAATMPPVLADCLAWAVEYRRRCYLYPNCPESWERHTADSMSDGYAQEHCRSMLAALAALGIRLQEGQQAYALLAAEECRQREKASLPPEPSPLSEVEVSSFVDEFFTKLDAPKEEVPT
What are the official names of this protein?
Uncharacterized 18.9 kDa protein in mobE 3'region, ORF 3.
Protein: HIS5_CUTAK
Sequence: MSDPVRVGIIDHGSGNLHSARRALRQVGAEVIVSNDPSALLDTDALVLPGVGALAVCMTGLRAMGGARLVRQWVDEGRPLLGICVGHQMLFERGRERDVDVKCLGVLPGVVEELPAERLPHMGWNTVTPATDSALFQGVQERFYFVHSYGVVVTGPHDHFTTATHQGATFVAAAEYGPVTSTQFHPEKSGIAGLALLTRWLNQLS
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTRD_LACCA
Sequence: MADQPVQVNKLKTKITKGDMFKTFVFENFQQASFNFERIHALAFCVDMIPTIKRVYSKKEDQVAALKRHLVFFNTTPAMCGPIVGVTMALEEGRAAGEPIDDGTINSFKVGLMGPLAGVGDPLMWGTLRPILAALGASLALQGSWLGPILFFVAFNAVRLSLKWYGLQLGFSRGLALVKDMSGNLLQKITEGATVLGLFIMGILVTKWTTINVPLVVSKTTVNGKTTVTTLQNILDQFCPGLLALGWTLLCMYLLRKKVSPILLIFALFGVGIVGYWLGILK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.  The enzyme II SorABCD PTS system is involved in L-sorbose transport.
What are the official names of this protein?
PTS system sorbose-specific EIID component, EIID-Sor, Sorbose permease IID component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S39A9_MICUN
Sequence: MDDFSSISLLSVAMLVGCYVAGTIPLAVNFSEEKLKLITVLGAGLLCGTALAVIIPEGVHAIYEEILEGGHHSHGQAGVVEVSEAKGDAESVLSGGGKHEHSHEQLHACIGVSLVLGFVFMLLVDQIGSSHVHSTEDPESARVTSSKITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVLAMLTFLGLSQSSKEALSDINATGVAMLFSAGTFLYVATVHVLPEVGGGGHSHAASGGNGGKGLSKVEVVALVLGCLIPLVLSVGHHH
What is the function of this protein?
Has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through G protein activation and are required for the androgen-dependent apoptotic response (PubMed:25014354, PubMed:28633436).  Upon androgen binding, mediates apoptosis by directly activating a stimulatory G protein that leads to increased cAMP levels and MAP kinase activity and which is accompanied by increased intracellular free zinc levels (PubMed:25014354, PubMed:28633436).
What are the official names of this protein?
Zinc transporter ZIP9, ZIP-9, Solute carrier family 39 member 9, Zrt- and Irt-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
Protein: KLH14_MOUSE
Sequence: MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGGGVGGQDGLGAPKDQQQQQQPQQQPPQQQQPPPQEEPGTPSSSPDDKLLTSPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLLLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKHLYVIGGRNETGYLSSVECYNLDTNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYCPEKGTWTELEGDVAEPLAGPACATVILPACVPYNK
What are the official names of this protein?
Kelch-like protein 14, Protein interactor of Torsin-1A, Printor, Protein interactor of torsinA.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum membrane. Note=In neurons, located in cell bodies, as well as in neurites.
Protein: HUNB_DRODA
Sequence: WYSSMFAANIKQEPISHHHHHHHAHHSHHAHDSNSNSNASSPHQSPLPSPNPPSHTNLQLEQYLKQQQQQQQQHQHQQQQQPMDTLCAAAMTPSPSNNDQNSLGWLVGLPNPMQTIMPANMRPSPTATTATAAAAAPTTTAAAIALQANDKLQALTPPMDVTPPKSPAKSQQSCAEPEKEHDLMSNSSEDMKYMA
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNCB_NEIMB
Sequence: MTGIIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIREDLEAELDALCQLRFTHDELGYLRSLRFIKSDFVDYLELFQLQRRFVEIGTDDKDRLNIRIEGPMIQAMFFEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEIAAAQNPDEPPFLISDFGTRRRYKLAWQEHVIRTLLEAAPGIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNFQKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDKAYAHYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLKLVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDVPEPETP
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: NSG2_MOUSE
Sequence: MVKLNSNPGEKGAKPPSVEDGFQTVPLITPLEVNHLQLAAPEKVIVKTRTEYQPEQRNKGKFRVPKIAEFTVTILVSLALAFLACIVFLVVYKAFTYDHSCPEGFVYKHKRCIPASLDAYYSSQDPSSRSRFYTVISHYSVAKQSTARAIGPWLSAAAVIHEPKPPKTQGH
What are the official names of this protein?
Neuronal vesicle trafficking-associated protein 2, Neuron-specific protein family member 2, Protein 8.5, Protein p19.
What is the protein family that this protein belongs to?
Belongs to the NSG family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane. Cell projection, dendrite. Endosome membrane. Early endosome membrane. Late endosome membrane. Lysosome lumen. Cytoplasmic vesicle membrane. Golgi apparatus, Golgi stack membrane. Endosome, multivesicular body membrane. Note=Endocytosed from the cell surface, thus entered into early endosomes, trafficks to late endosomes and degradates in lysosomes (By similarity). Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies (PubMed:7829526). Found in both stationary and motile endosomes (PubMed:28874679).
Protein: CTSR_STAS1
Sequence: MHNMSDIIEQYIKKLFEDTNEDVVEIRRTNIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDETGYINHLLQLVGPSISQQQAYYIVDGLLDKSYINEREAKMIYAVIDRETLKMDILSRDIIRANIIKRLLHVINYY
What is the function of this protein?
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
What are the official names of this protein?
Transcriptional regulator CtsR.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: GPDA_STRSY
Sequence: MTKQTIAILGPGSWGTALGQVLNDNGHTVRIWGNVPEQIDEINKEHTNKRYFKDVILDENIKGYKDLSEALDGVDAVLFVVPTKVTRLVAKQVAQALKHKVVVMHASKGLEPDSHKRLSEVLEEEIPAELRSEIVVVSGPSHAEETIVRDLTLISAASKDLETASYVQNLFSNHYFRLYTNNDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAIIARGLTEITRLGVAMGANPLTYSGLSGVGDLIVTGTSVHSRNWRAGDQLGRGEKLEDVERNMGMVIEGISTTKAAYELAQELGVYMPITQAIYKVIYQGAGIEDAIKEIMTGEFRHENEWH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APC13_HUMAN
Sequence: MDSEVQRDGRILDLIDDAWREDKLPYEDVAIPLNELPEPEQDNGGTTESVKEQEMKWTDLALQYLHENVPPIGN
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
What are the official names of this protein?
Anaphase-promoting complex subunit 13, APC13, Cyclosome subunit 13.
What is the protein family that this protein belongs to?
Belongs to the APC13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL28_MICLC
Sequence: MAAHCQVTGAGPGFGHSISHSHRRTKRRFDPNIQKKTYWVPSLRRNVTLTLSAKGIKTIDVRGIDAVVADLIAKGVKL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NEU2_ANSAN
Sequence: ALADTALRQCLPCGPGNRGRCFGPGICCGVELGGCYVGTAETRRCAEEDYLPSPCQPGGQPCGSGGRCAADGVCCSADTCAADASCLEEGSERAEEAAEKNLTVLDGSAGDLLLRLMQLAGRQQGRQPGLL
What is the function of this protein?
Neurophysin 2 specifically binds vasopressin.
What are the official names of this protein?
Neurophysin 2, MSEL-neurophysin.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAA_AGRFC
Sequence: MMKNLDQNFDAILITGPTASGKSALALRLARERNGVVINADSMQVYDTLRVLTARPSDHEMEGVPHRLYGHVPAGSAYSTGEWLRDISGLLSDLRGEGRFPVIVGGTGLYFKALTGGLSDMPAIPDDLREGLRARLIEEGAAKLHAELVSRDPSMAQMLQPGDGQRIVRALEVLEATGKSIRDFQRASGPMIIDPERAQKFIVLPERPVLHDRINRRFEAMMDSGAVEEVQALLALNLAPDATAMKAIGVAQIADMLTGRMGAAEVIEKSAAATRQYAKRQMTWFRNQMGDDWTRIQP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: YIDC1_STRPN
Sequence: MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAPMAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEPHQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHTEGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLMIVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSKPSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 1, Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSU1_ARTOC
Sequence: MPSGSGFQNIEEAGEKARRRDDWIAISNFHPGWFSVNMGTGITAILLQNLPYQFPGLHYIAVVLFVLNVIIFFFFLTISITRYALWPEKFKAMLAHPAHSMLLGTFPMGFATIINCIIFICVPVWGDWAARFAWGLWWVDATVSIAICYFVPFMLMTKHTSSLETMTAAWLLPIVAPVVAAASGGVVADALKNDTHALITILVCYVMWGSAVPLAMVILVIYFQRLALHKLVPRAAIVSALLPIGPLGQGGFGLMQLGVVARRVFPRLDFLAPIAGEIFYVMGAFIAMIMWGFGLIWLWFALASFTRGKFYFNIGWWAFTFPLGVFTTATTQMGKEFNSVVFDVLGTFFSIVVAAMWVMVFALTVYKSCTKELFK
What is the function of this protein?
Sulphite efflux pump required for the secretion of sulphite as a reducing agent.  In the presence of sulphite, cystine in keratin is directly cleaved to cysteine and S-sulphocysteine, and thereby, reduced proteins become accessible to hydrolysis by a variety of secreted endo- and exoproteases.  Excretion of sulphite mediated by an efflux pump represents also an detoxification pathway for dermatophytes during infection of the epidermal stratum corneum, hair and nails, which are rich in cysteine (By similarity).
What are the official names of this protein?
Sulfite efflux pump SSU1.
What is the protein family that this protein belongs to?
Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMG_WOLSU
Sequence: MRDFDVIVVGGGHAGIEAAHASARMGCKTLLLTILVEQIGAASCNPAIGGLAKGHLVKEIDALGGVMGKVTDLCGLQFRTLNASKGPAVRGTRAQIDMDRYRIMMRNLCLTTPNLTVAQEMVEELIVEEGAVLGVRTQIGREYRSAKVIMTTGTFLNGLVHIGNRTSSNGRVGEPSSIKLSESLRSLGLEVGRLKTGTCARIASESIDFSVMEQHPGDLPPPPFSFSTKKEEFAPTQLPCYVTYTNEKTHEIIRSNFHRAPMFTGQIEGIGPRYCPSIEDKVNRFKERERHQIFVEPQTLEATEYYLNGLTTSMPFDVQEAMIRSMAGLQNARIVRYGYAIEYDYVNPVELKHTLETKKIKNLYLAGQINGTTGYEEAGAQGLAAGINAALSVKGEEPFVLRRDEAYLGVLIDDLVTKGTKEPYRMFTSRAEYRLLLREDNAEFRLLRHGARFGLVEEEALLALQKDEQSIHGGLVHLRESSATPSKETLAFLEEMGEEKINDKTTWLAIAGRKSFDEAKLRKISPLFEEMSERALGQVLIEAKYASYIQKQQESVGSMQEMLKVKIPEGFIFDTVPGLSLEVIEKLKRFNPPTLFAASEISGITPASLDVLHLYIHLRGKESVD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS9_YEAST
Sequence: MHSHHSHSGDYSAHGTDPLDSVVDQVVNLNFHTYCLTEHIPRIEAKFIYPEEQSLGKNPEEVITKLETSFKNFMSHAQEIKTRYADRPDVRTKFIIGMEIESCDMAHIEYAKRLMKENNDILKFCVGSVHHVNGIPIDFDQQQWYNSLHSFNDNLKHFLLSYFQSQYEMLINIKPLVVGHFDLYKLFLPNDMLVNQKSGNCNEETGVPVASLDVISEWPEIYDAVVRNLQFIDSYGGAIEINTSALRKRLEEPYPSKTLCNLVKKHCGSRFVLSDDAHGVAQVGVCYDKVKKYIVDVLQLEYICYLEESQSPENLLTVKRLPISQFVNDPFWANI
What are the official names of this protein?
Histidinol-phosphatase, HolPase.
What is the protein family that this protein belongs to?
Belongs to the PHP hydrolase family. HisK subfamily.
Protein: VID27_YEAST
Sequence: MNILKKFMESGNKPELITIPSGQFNLLRSKNSPKAALECIYNNATLSVRKIGKFDYELAVYRVEDDSEGGTGDEAENFEDDTISVLSTQSKKKEEEWSVEISDKIMFHKTWDKQGNVALVWENLRGDEQDEKVQFVVAADVSFSDVEQFIQTVYRCQFEVRNKKSSLTASADDLKEIEHRSTRLFVQDDDDELDSSSDDFQDAKDTSFEHEKESEILERTPSPLKKVPEGEYCCLVMSSLYMYDPIQEKFILQEPVVKVAIIDTGKYEFWLAIEGKDNRLGTQVAPNINPTFELATDAFLFNYTLQNITLSYMLKFKDLDKCIQFRFAWVKCLWMTLNKETWTDVPEKEKDYILDSSSVPLEKQFDDILHIDDRSNEERDKESSESENDSEDEDDENDHSKRIISSEAFEEPRRATSKGNSSLTVAFRNNRSYVTRDNRIGVFKTDDEDDSLEFVAAIKNISNLGGKSIDPHKPMLYMEDRNLILTDGENENKLYKMDIERGKVIEEWSTGDKNVVQYGPTKKFDQMTPEQTIVGVSQKGVFKIDPRINGKNKIAVDESKDYVGKYNFSSIGTTESGYIAIGSEKGDIKLYDRLGIRAKTAIPSLGQAIKFITTSADGKWLLATCESTLLLMDLKIKDGKNAGNIGFLKSFPASENVKTYVLKIRPEHSASILTYTKKPIRFTKAYFNTGIGQQEQTIVTSTGPYAISWSLKGILNQDGSNNYPYRIRRYNADVVADNFEFGSDKKVIVALKDDVSLSKVKSFKQPSKGVLMPSASLQDFYG
What is the function of this protein?
Has a role in the negative regulation of gluconeogenesis.  Required for vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase).
What are the official names of this protein?
Vacuolar import and degradation protein 27.
What is the protein family that this protein belongs to?
Belongs to the VID27 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1C_SYNY3
Sequence: MTSGIDLQNSFLQSLQGFGLPPGLAKLFWIPLPSILMIIGATVGVLVVVWLERKISAAAQQRIGPEYAGPLGVLQPVADGIKLVFKEDVVPAKADPWLFTLGPVLVVLPVFLSYLIVPFGQNLVITDINVGIFLWIALSSIAPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLSLAVLAIVMMSNSLSTIDIVDQQSGYGILGWNIWRQPVGFLIFWIAALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYLGSYVNLVLSALVFSVLYLGGWDFPIPLENVANWLGVAPTTSWLQVLMAALGITMTVLKSYFLIFIAILLRWTVPRVRIDQLLNLGWKFLLPVALANLLITAALKLTFPMAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.