PharMolix/UniProtQA huggingface dataset:
Protein: RLMH_GEOUR
Sequence: MKMRVLWVGKTQEEWVRRGIDEYAGRIRRYTPLELAEAKEEKGAAAEAMREREGERLVKLLPRNARLILLDERGEQLSSPDLAGFIAANRDGGVQELAFAIGGAYGFSDSFRSMAYKTIALSRMTFTHQMVRIFLLEQIYRGFTIINGEPYHH
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IKBD_MOUSE
Sequence: MEDSLDTRLYPEPSLSQVGSWRVSSLPSGSPQLPSPTGPSLETARAHILALGPQQLLAQDEEGDTLLHLFAARGLRWAAYAAAEVLQMYRQLDIREHKGKTPLLVAAAANQPLIVEDLLSLGAEPNATDHQGRSVLHVAATYGLPGVLSAVFKSGIQVDLEARDFEGLTPLHTAVLALNAAMLPASVCPRMQNSQARDRLTCVQMLLQMGASHTSQEIKSNKTILHLAVQAANPTLVQLLLGLPRGDLRAFVNMKAHGNTALHMAAALPPGPPQEAIVRHLLAAGADPTLRNLENEQPVHLLRPGPGPEGLRQLLKRSRTAPPGLSS
What is the function of this protein?
Regulates the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity.  Functions in the regulation of inflammatory responses (PubMed:11931770, PubMed:15749903, PubMed:16410444, PubMed:16413922, PubMed:17641034).  Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR) (PubMed:25282160).  According to PubMed:11931770, it may also regulate TCR-induced negative selection of thymocytes (PubMed:11931770).
What are the official names of this protein?
NF-kappa-B inhibitor delta, I-kappa-B-delta, IkB-delta, IkappaBdelta, IkappaBNS.
What is the protein family that this protein belongs to?
Belongs to the NF-kappa-B inhibitor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YEGS_YERPS
Sequence: MPHTLLILNGKESGNPEVREAVKNVRDEGLTLHVRITWEHGDAKRYVEEAATLAVSTVIAGGGDGTINEVATALMSLPADKRPCLGILPLGTANDFATGCNIPLQIENALQLAVKGRAVAIDLAQVNGEHYFINMATGGFGTRITTETPDKLKAALGGVSYFIHGLMRLDALKADSCKIHGPDFHWSGDALVIGIGNGKQAGGGQLLCPDALINDGLMQLRLLTAKELLPAVLSTLFNGEKNKNVIDATVPWLDITAPNDITFNLDGEPLSGRYFHIEILPHAIQCRLPPNCPLLG
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS-like.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_CAMJ8
Sequence: MARYRGPVEKLERRFGVSLALKGERRLAGKSALDKRPYAPGQHGARKGKISEYGLQLREKQKAKFMYGVSEKQFRRLFAEAARREGNTGVLLIQLLEQRLDNVVYRMGFATTRRFARQLVTHGHVLVNGKRVDIPSFRVEAGAKIEIIEKSKNNPQITRAIELTAQTGIVAWVDVEKDKRFGIFTRKPEREEVVIPVEERFIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: OS28_PLAGA
Sequence: MKIPSLYFFFFIQIAIILTIAAPSDDEPCKNGYLIEMSNHIECKCNNDYVLTNRYECEPKNKCTSLEDTNKPCADYARCLEDPYKDNKSNFYCLCNRGYIQYEDKCIQAECNYKECGEGKCVWDGIHEDGAFCSCNIGKVINPEDNNKCTKDGDTKCTLECAQGKKCIKHDVYYMCGNDNSGSGSGGGGGGGNSPPPSSGNSTLSLFNALNIVFLIAVIYII
What are the official names of this protein?
28 kDa ookinete surface antigen, Pgs28.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: 1ATF_PRRSS
Sequence: MSGTFSRCMCTPAARVFWNAGQVFCTRCLSARPLLSPELQDTDLGVVGLFYKPKDKIHWKVPIGIPQVECTPSGCCWLSAVFPLARMTSGNHNFLQRLVKVADVLYRDGCLAPRHLRELQVYERGCSWYPITGPVPGMGLFANSMHVSDQPFPGATHVLTNSPLPQRACRQPFCPFEEAHSDVYRWKKFVIFTDSSPNGRFRMMWTPESDDSAALEVLPPELERQVEILTRSFPAHHPINLADWELTESPENGFSFGTSHSCGHIVQNPNVFDGKCWLTCFLGQSAEVCYHEEHLANALGYQTKWGVHGKYLQRRLQVRGMRAVVDPDGPIHVEALSCSQSWVRHLTLNNDVTPGFVRLTSIRIVSNTEPTAFRIFRFGAHKWYGAAGKRARAKRATKSGKDSALAPKIAPPVPTCGITTYSPPTDGSCGWHVLAAIVNRMINGDFTSPLPQYNRPEDDWASDYDLAQAIQCLQLPATVVRNRACPNAKYLIKLNGVHWEVEVRSGMAPRSLSRECVVGVCSEGCVAPPYPADGLPKRALEALASAYRLPSDCVSSGIADFLADPPPQEFWTLDKMLTSPSPERSGFSSLYKLLLEVVPQKCGATEGAFVYAVERMLKDCPSPEQAMALLAKIKVPSSKAPSVSLDECFPAGVPADFEPAFQERPRSPGAAVALCSPDAKGFEGTASEEAQESGHKAVHAVPLAEGPNNEQVQVVAGEQLELGGCGLAIGSAQSSSDSKRENMHNSREDEPLDLSHPAPAATTTLVGEQTPDNPGSDASALPIAVRGFVPTGPILRHVEHCGTESGDSSSPLDLSFAQTLDQPLDLSLAAWPVKATASDPGWVRGRCEPVFLKPRKAFSDGDSALQFGELSESSSVIEFDQTKDTLVADAPVDLTTSNEALSAVDPSEFVELRRPRHSAQALIDRGGPLADVHAKIKNRVYEQCLQACEPGSRATPATREWLDKMWDRVDMKTWRCTSQFQAGRILASLKFLPDMIQDTPPPVPRKNRASDNAGLKQLVARWDKKLSVTPPPKSAGLVLDQTVPPPTDIQQEDATPSDGLSHASDFSSRVSTSWSWKGLMLSGTRLAGSAGQRLMTWVFLKFTPISQLLYSHFSRRGALWLQAIGCLQVLFYLLSCSVVLTQYSDAFPYWVSFLVLCGVFVWVFLVLGWLLLYFYSRLHPTQSVLLVTTIRRNVMLSFWLLSSANFGNLCAALWLAPQVSYVSSLASYSVGHVISGMLSYVYACLQIWPFLLFMWCPKGVVTSVGESV
What is the function of this protein?
Nsp1-beta transactivates the programmed ribosomal frameshifting event leading to the expression of the 1aTF polyprotein.
What are the official names of this protein?
Truncated polyprotein 1aTF.
What are the subcellular locations of this protein?
[Nsp1]: Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Nsp1-alpha papain-like cysteine proteinase]: Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Nsp1-beta papain-like cysteine proteinase]: Host cytoplasm. SUBCELLULAR LOCATION: [Nsp2TF]: Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
Protein: RBFA_LACLS
Sequence: MGNSFRSDRVAVEIQREINDILRNKVRDPRVQDVNITDVQLTGDLSQATVYYSLLSNLASDNEKAATALKKATGLFKSELAKRMTIFKIPDLTFAKDESVEYGSKIDELLRGLNDKSEY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGTA_CANAX
Sequence: MQHGIKRVKLSEEAKRLKLEKDQIKIKNYRQLTDEIFELRANENYSDEALIKTNELLIINPEFYTIWNYRREILINNYSSSNDKDDQIYEDILNQDLNFVLVQLKKFPKCYWIWNHRRWLLFELVKLGKVNWKYEFGVVSKLLDLDQRNFHGWHYRRFVVKNMELECKNDTTLILKINLDEFNYTTLKIQKDFSNFSAWHNRTKLIPKIYNLIQQQQQQQQKDGKIFGDLPGIELFQNPILLLKNDLEMIKTGVYMSPEDTSVWLYLYWLLTDDLFTNAFKSHQQDYMNILHEQLQLINEVNEMEKEDTGQDNVGCLKSMIFINALIQNENNKPVLTEQVKSCLKQLAKIDPLRKNKYLDQLAGNAPIFHH
What is the function of this protein?
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both cysteines may become modified.  Acts on YPT1 and SEC4 (By similarity).
What are the official names of this protein?
Geranylgeranyl transferase type-2 subunit alpha, GGTase-II-alpha, Geranylgeranyl transferase type II subunit alpha, PGGT, Type II protein geranyl-geranyltransferase subunit alpha, YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: TATA_MOOTA
Sequence: MFGLGAPELILILILALIIFGPGKLPEVGRALGKGIREFKNATNSVTEEIKEAAKIDDGNNNSDKEKATRQAS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RPOC_BRASB
Sequence: MNQEIMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMTLKDLERILYFEYYVVLEPGLTALKDRQLLSEDEYLKAQDEYGQDSFTAMIGAEAIRELLRGLELEKLEQTLRAEMQETDSDIKHKKLAKRLKIVEAFRHSGNKPEWMIMTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELRLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIMREGMNGQGMTFGNMAELEHALHAKAIHLHSKIKYRWEGMDETGKISKRWIETTAGRVMLGNVLPRHPRISYEIINKLMTKREISGVIDQVYRHCGQKETVIFCDRIMALGFYNAFKAGISFGKDDMVVPAGKWKIVDTTRTLAKDFEQQYNDGLITHGEKYNKVVDAWSKASEEIAKEMMKEISVTKKTATGADADINSIYMMSHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITQDDCGTHLGIKMRAIVDAGTVVASLGSRILGRVPCDDVRDPATNAVLVKAGTLMEESHIDAIQQAGVQEVKIRSALTCELVNGICKMCYGRDLARGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQLNEQSFVESNFEGRVVIKNKAIARNSEGHLIAMVRNMVVTIVDPDGSERATHRIQYGARMHVDDGDMIKRGQRIAEWDPYTRPILTEAEGTIGFEDLTEGLSISETLDESTGIAKRVVIDWRGTRGGADLRPAIVIKGKDGKVLKLARGGDARYMLSVDAILSVDVGTTVKPGDILARISTESAKTRDITGGLPRVAELFEARKPKDAAIIAEIAGTIRFGRDYKNKRRISIEPVDKTEEPREYLIPKGKHIHLQDGDIVEKGDFIVEGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKIEVTDQGDTDMIAGEQVDKIEFDALNAKAVEEGKKPATGNPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKIDPLEGLKENVIVGRLIPAGTGASMARIREVALKRDKLILDEREKQAAIVPSQPEPQPLALPPAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RPOZ_LATSS
Sequence: MIVYPSIDKLLENVNSRYSLAVLASKRAHQIEAGDLKMLSEYKSPKTVGMAMEEIAAGNVTIDPDSLMLEKDAEKMDKLSQKDGE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PTH_MYCA9
Sequence: MPVLSDDAVLVVGLGNPGPNYAKTRHNLGFMVADLLAAKDGATFKPHKKSGAEATTIRLGGRAVNLAKPRTFMNTSGPQVAALAKFFSVPPANVIVMHDELDLDFGTVRLKLGGGEGGHNGLRSVSQSLGTKDYLRVRLGVGRPPGRKDPAAFVLENFAKAETDQVPLLCEQGADAAELLIRLGLEAAQNQVHAWG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_LEPIC
Sequence: MESFVDEVAIEVFAGHGGAGSVHFRREKYVEFGGPDGGDGGIGGNVVIRPNLSMYTLDKYLSKRKFKAQAGFPGVGDNCSGKKGEDLVLFVPLGTQIYDEETGDLLFDFVSDSQEFVVARGGRGGKGNAHFKTSTNQTPRFAQPGEEGEYKFLRLSLKLLADVGIVGLPNAGKSTLISKITDAHPKIAGYAFTTLSPNLGVVKRRGDIFRFTIADIPGIIEGASMGIGLGLSFLRHIERVKGILYLFDASSLDIEEDLKMLRNELSTYNPELLNRPYLIVLNKIDIWNDPEFTKDVIAKVSHLGKVVAISADQEVNLEELLENMDEVFFKNEIEKILNPIKDTKPISLDESDIFES
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARHGG_HUMAN
Sequence: MAQRHSDSSLEEKLLGHRFHSELRLDAGGNPASGLPMVRGSPRVRDDAAFQPQVPAPPQPRPPGHEEPWPIVLSTESPAALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAARRDPKLLPAPSFSLDDMDVDKDPGGMLRRNLRNQSYRAAMKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAKNKKTLGRKRGHKGSFKDDPQLYQEIQERGLNTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVELGILDQLSTEERKRQEAMFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV
What is the function of this protein?
Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP.  May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2.  May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 16, Ephexin-4.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG82_BPML5
Sequence: MTPKPIRVFVYKNLHRTHREGKPWYSVQALEGDFKGRVIHRSGHVLLAHAKGVVRPAGRDKVRRERRKVVHAGIVGELISLLPQDFVGSKIAYNPYENDTFVHANTQAPFLGADRVYLSDSGVRAA
What are the official names of this protein?
Gene 82 protein, Gp82.
Protein: ASB17_MACFA
Sequence: MSKSNKLCRKTSCPRSNIFCNLLDKIVKRPSLQFLGQWGYHCYEPRIYRSLAKILRYVDLDGFDALLTDYIAFVEKSRYRFEVSFNLDFTEICVNTILYWVFARKGNPDFVELLLKKTKDYVQDRSCNLALIWRTFTPVYCPSPLSGITPLFYVAQTRQSNIFKILLQYGILEREKNPINIVLTIVLYPSRVRVMVDRELADIHEDAKTCLVLCSRVLSVISVKEIKTQLSLGRRPIISNWFDYIPSTRYKDPCELLHLCRLTIRNQLLTNNMLPDGIFSLLIPARLQNYLNLEI
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 17, ASB-17.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: KCD19_BOVIN
Sequence: MEEPGMPHESAEDLFHFNVGGWHFSVPRSKLAQFPDSLLWKEASALTSSENQRLFIDRDGSTFRHVHYYLYTSKLSFSSCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADIPVAERASLNYWRTWKCISKPSEFPIKSPAFTGLHDKAPLGLMDTPLLDTEEEVHYCFLPLDLVAKHPSLVTEDNLLWLAETMALIECECSEFRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEIPELSEAVRLYRMNMGGCSRTSCPPPSPGKGGRSAGLESVKPLYMMALGLLVKYPDSALGQLRIESTLDGSRLYITGNGVLFQHVKNWLGTCRLPLTETVSEVYELCAFLDKRDITYEPMKVALKTHLEPRTLAPMDVLNEEWTAEITVYSSQQIIKVYVGSHWYATTLQTLLKYPELLSNPQRVYWITYGQTLLIYGDGQMFRHILNFLRLGKLFLPTEFKEWPLLCQEVEEYHIPSLSEALVQCEAYKSWIQEKESENEEAFPIRRLHVVTEGPGSLVEFSRDTKETMACVPMEFQDCNDRTMWNKAKGTLARSSQIEEAEQYSQTIQMSLCRGAKRAGNPSTYSHCPGLCANPRHWGGHPESPPKKKCTTVNLTQKPETKDPPVTPMQKLISLVREWDMVNCKQWEFQSLPAPRNSSLEEATLQHSSGSEAVSQPSTSASWKGHSTASEKDPGPQAGAGAGTKDKGPEPNFNPYFPMKRAVALKDWGKQRSKERENPAFELTLPEASEGDNTGVILKVTHPPVVGSDGSCMFFEDSIIYTTHMDHLRRTPPPASPQPREVTFLSFSLSWEEMFYAQKCHCFLTDIILDSIRQNDPKAITAKVVSLVNQLWTLHISPKQFVVDLLAITGFKDDRHTQERLYSWVELTLPFARKYGRCVDLLIQRGLSKSVSYSVLSKYLQDG
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD19.
Protein: HIS7_PROM3
Sequence: MGIMTSLRQGDVHRVTAETDVLVRVGLDGCGQCNVSTGVAFLDHMLHQLSSHGLLDLEITATGDTHIDDHHTNEDVGIAVGQALSQALGDRRGIHRFGHFVAPLDEALVQVVLDCSGRPHFSYGLQIPSQRIGSYDSELVKEFFVAVVNNSGLTLHIRQLAGTNSHHIVEACFKAFARALRMAIEIDPRRAGAVPSSKGVLEQAGGQKS
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_COXB1
Sequence: MYAQPKLTSAEYVQHHMSHWKLNLHNFTFTDGGFWTLNLDTLIISVVLGALFILIFYIVARRATASVPGKWQNAIEMAVEAVDGTVKDSFHGDRSLVAPLALTIFIWVFLMNFMDLVPVDLIPRLFQMGGVEHFKAVPTADPTLTFAMSITVFVLVIFYNFKMKGAIGLGKEVLSRPFGWYLMPINVIFRLIDEGVKPISLALRLFGNLFAGELIFILIALLPWWSQFTLGMVWTLFHLLVITVQAFIFMMLTVVYISLAAESH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NQRA_KLEP3
Sequence: MIKITKGLDLPIAGMPLQQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKTPGVYFTAPASGVVSAIHRGERRVLQSVVIDIEGNEAVAFTRYAADALAELPRDTVQQQLLASGLWTALRTRPFSKTPRPGSVPAAIFVNAMDTNPLAAEPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPAGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHLNYQDAIAIGQLFLEGELNCERVIALGGPQVKSPRLVKTTLGASLDDLLAGELEEGENRVISGSVLSGTRAHGPHAFLGRFHLQVSVVREGREKELFGWVMPGKEKFSITRTTLGHFFKRKRFHFSTDTHGGERAMVPIGNYERVMPLDILPTILLRDLLAGDSDSAQALGCLELDEEDLALCTYVCPGKYEYGPALRSVLTQIEQEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: HSS1_SENVE
Sequence: MAESNKEAIDSARSNVFKESESLEGTCAKIGGYDFNNGIDHSKLLKSMVSTGFQASNLGDAMIITNQMLDWRLSHDEVPENCSEEEKKNRESVKCKIFLGFTSNLISSGVRETICYLTQHRMVDVLVTTTGGIEEDFIKCLASTYKGKFSLPGADLRSKGLNRIGNLIVPNDNYIKFEDWIIPIFDQMLIEQKTQNVLWTPSRMIARLGKEINNETSYLYWAYKNNIPVFCPSITDGSIGDMLYFHSVSNPGPGLVVDIVQDVIAMDNEAVHASPQKTGIIILGGGLPKHHICNANMMRNGADFAVFINTAQEYDGSDSGARPDEAVSWGKISSTGKAVKVHCDATIAFPLLVAETFAVKKEKASKVNGF
What is the function of this protein?
Catalyzes the transfer of an aminobutyl unit from spermidine onto putrescine.  The resulting polyamine homospermidine is a precursor in the biosynthesis of pyrrolizidine alkaloids.
What are the official names of this protein?
Homospermidine synthase 1.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: ENV17_DROME
Sequence: MLITTVHGQQIEINNIDTNHGYLLFSDKPVQIPSSFEHHCLRINLTEIDTIADYFEQRLRTDYHAPQVKFLYNKMRRELAGIALRHRNKRGLINIVGSVFKYLFGTLDENDRVDIQRKLETNAHNSVNLHELNDAIQLINDGMQKIQNYENNSNIINSLLYELMQFTEYIEDVEMGMQLSRLGLFNPKLLNYDKLENVNSQNILNIKTSTWINYNDNQLLIISHIPINFSLINTVKIIPYPDSNGYQLEYTDTQSYFERENKVYNNENKEINNECVTNIIKHLKPICNFESIHTDEIIKYIEPNTIVTWNLTQTSLKQNCQNSFNNIKIKGNKMIKVTQCKIEINSIILSENLFKPEIDLTPLYTPLNITKIKTVKHNDINEMISQNNITLYIFMTTVIIILILLYLYLRYVSFNPFMMLYAKLKLRKNQNQNTAQQIEMEDVPLPLLYPSIPAQV
What are the official names of this protein?
Retrovirus-related Env polyprotein from copia-like transposable element 17.6.
Protein: TSAC_SHESM
Sequence: MLQLHPSEIKDIVLNGGVIAYPTEAVYGLGCDPDNDTAIQKLLAVKQRPWQKGLILVASEFSQLVDYVDESQLSAEQLEFAFSKWPGPFTFVMPIKPHVSRYLCGEFDSIAVRVSAHEGVRALCQALGKPLVSTSANLAGEDPALSGDEILNAFEGKIDALVLGSLGEQRQPSTIIDARSGKILRNGQ
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_PROMS
Sequence: MIKTSWEGNCFLNFFNNKVSLGNVDKTIFKSKSTSPYKLLKSTHDQEGRCILPVLHTAGGLVGGDLLVFEVNLEKNSKVLLTTSSAQKVYGSVGISKINPKGSFSKQKNLINILDNSHLEYLPQETIIFANGLYEQIFKVSISETSSFLFTDLIRLGRSSSGESIESGVFRSRLEIIRNNDLLDDWEYVDQIELSKASFVAKSGMDYMPVFGSLIWICEKDFSKSKINNLVRKIKKIFNKTNNNLSIGILENGISVRFLGSSSQDARKCFFRIWKQIRSVSGFCEPKYQGVWPLQDSMNY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFKC_BACSU
Sequence: MRMKETLTEIFQNKIVDILLVAVILWIGVFIINRLVQLFFKRTDFIEEKKEKTIESLVRSVTQYTATIGFIFYVISLFVHDFGKILAGAGVAGIVIGFGAQSLIKDVLAGVFLIYERQLHKGDYVTVNNLFNGTVEEIGLRSLQIREWSGKLLTISNGEVRQIENYNIDFMRITESFLISFKEDPDRVYSVLEEACDMLNEELRDSLKRDEFGNPTEPFQIHGITALNKINRGVEFTVKGMVKDDDYFSASLAVRRVLVRQLYQNNVQMLEEAVRIERTQ
What is the function of this protein?
May play a role in resistance to osmotic downshock.
What are the official names of this protein?
Uncharacterized MscS family protein YfkC.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IL17C_HUMAN
Sequence: MTLLPGLLFLTWLHTCLAHHDPSLRGHPHSHGTPHCYSAEELPLGQAPPHLLARGAKWGQALPVALVSSLEAASHRGRHERPSATTQCPVLRPEEVLEADTHQRSISPWRYRVDTDEDRYPQKLAFAECLCRGCIDARTGRETAALNSVRLLQSLLVLRRRPCSRDGSGLPTPGAFAFHTEFIHVPVGCTCVLPRSV
What is the function of this protein?
Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner.  Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways.  Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G.  Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.  Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype.  Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
What are the official names of this protein?
Interleukin-17C, IL-17C, Cytokine CX2.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGA_YERPS
Sequence: MKERSTELVQGFRHSVPYINAHRGKTFVVMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDSNLADHNYEPIYHKHTRVTDARTLEMVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAIHRQLDNGAIVLLGPVAVSVTGESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTDSEGNIISELFPNDAQKRIEDLEQDGDYNSGTVRFLRGAVKACRSGVRRSHLLSYQEDGALIQELFSRDGIGTQIVMESAEQVRRATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIERDNLTIACAALYPFPDEHIGEMACVAVHPDYRSSSRGEMLLNRITNQARQMGLKKLFVLTTRSIHWFQERGFTPAEVDVLPIQKQELYNYQRRSKILLADL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.