PharMolix/UniProtQA huggingface dataset:
Protein: COAD_BIFA0
Sequence: MTIAVCPGSFDPVTNGHIDVITRCCRLFDEVHVVVAVNAMKKPLFTETERVDIIKHALADSGMTNYVVAWTDGLITDYCRKVDSPVIVKGLRQNGDYEAELGMALVNRHLAYVETMFLPANPVLEHISSSVVKDVARHGGDITGMVPDYVVPLLEKALR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_GRABC
Sequence: MLIDFIKMHGLGNDFVVFDARKGPSLALSGSQAAAIADRRTGVGCDQLIVLEPSTVADAFMRIYNPDGSESGACGNATRCVADLLHRDGIAAPCMETVAGLLLAEINGNGICIDMGQPGLGWRDVPLAREMDTLFLPLEAPGLKMPAACSMGNPHATFFVADLAELDIPVTGPLLERHPLFPERANIGHAQMLSRSHIRLRVWERGAGLTLACGTGACATLVNAVRRGLAEREAVVELDGGQLLIHWREQDGHVLMTGPAATVFHGRIALESITG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_XANAC
Sequence: MPMPTVSMSPALTALIERAVARVRQSLPVEQAWPGGEFDRQLAQVALASEFALDTLARQPALLQHLAQPDPPPLPLPQFDPAQPQLWPAQLRRYRSAESTRLVWRDVLGLDSVEATLAGATQLAEHCLQCGLQALEQQFHTRHGKVVAADGSVQRLVVFGLGKLGGGELNFSSDVDLVYAYPQGGQSDGARPLAAEEYFARLGQQLARLLDETTADGFSHRVDLRLRPFGTAGRVALSFAGMDQYFQREGRDWERYAWLKARAVAGDIDAGEAWLETLRPFVYRRYLDFTALDGLREMKAAITAEVARHDRLDDIKRGPGGIREIEFLAQSLQLIRGGREPSLRERRLLPALQALVAAGQIDQENGQALSTAYRFLRRLENRLQMLRDAQTHALPQAPLDRERIALGLGYAQWSALLDALAPQRARVAAEFAELLAPRVRATAPDALADYWRALPDGDAAPLAGIGLNDPDGAHRALADFAQSSGVRALSDSARARLDRVMPALLHAATRASQPDAAVRRMLGLLQATLRRTSYLALLDEQPSALARLVDVLSRSALLAERLAAYPLLLDELLDTRISGPLPDRAALHAACAHTLHIDDTEAALRELNERRLALSFRIALATLDGRQQAVESTRQLAWLAEAVVQTVLHLARSDMLAAHGHVPGGSFAIVGYGSLGGLELGFGSDLDLVFLYDHPREVDASDGKRPLDAGRWFARLAQKVMALLAAETGAGRLYDIDVRLRPDGGKGALVSSLASYREYQRDRAWTWEHQALVRARAVAGDAALCDAFAQVRRDTLMRVRDTAQLHEDVRKMRARMRAELDRSDAGRLDLKQGAGGLVDLEFVLQAGVLGLAAQQPQLLDACDTPALIDALARTHWLPDESAAPLHQAHATLVDAGLSCTLDRRPRLIAPTPAIQQARGIIFNAARGQGLTFPLGKDETAL
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: MTNK_BACAH
Sequence: MGYYSLTEVTAVQYAKEHGYFEKKANVVCHEIGDGNLNYVFKLDDGEKSIIIKQALPYAKVVGESWPLSIKRATIESKALQIFAKYVPEYVPVVYSHDEELAVTVIEDLSRLTITRKGLIDGEEYPLLSQHIGRFLANVLFYTSDFGLQSEEKRVLEGTFVNPDLCKITEDLVFTDPFGHYDTNDYEPELQLTIDELWSDKTLKLKVAQYKYKFLTRKEALIHGDLHTGSIFSSPSETKVIDPEFATYGPFGFDIGQFIANLLLNALSREEEQRGVLFFHIEKTWSYFVETFTKLWIGEGVEAYTKEKQWLPIILQNIFTDAVGFAGCELIRRTIGLAHVADLDEITNKETRIQAKKQALSLGKELIKYESKNADIQLFRTLFQQTVSGGIKA
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase, MTR kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: PHF7_RAT
Sequence: MRTIKEKKEHPRLRKTARTKKVTHRKLSSGPVCLLCFQEPGDPEKLGEFLQKDNLCVHYFCLILSSKLPQKGQPNRGLHGFMPEDIKKEAARASRKVCFVCKRKGAAIRCQKDQCVQNFHLPCGQERGCLSQFFGEYKSYCGKHRPTQNIHQRSFGESCVLCCEDLSRASVENIRSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDCSSLRPNSKKWECNECLPASTEDSVSENLGDTPCCSSTFCPHEPFLRATSLEENPGSSWTNWLQPSLLEKPESSSGSSCQSWRSKGIKVTKDCKKSK
What is the function of this protein?
May play a role in spermatogenesis.
What are the official names of this protein?
PHD finger protein 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: PETG_PORPU
Sequence: MVEPLLSGIILGLIPVTLSGLLVAAYLQYQRGNQLGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS13_DEIGD
Sequence: MARIAGVDLPREKRVEIALTYIYGIGLTRAKEVLARTGVNPDTRVKNLSETEQSALREAIEKTYKVEGDLRSEVGQNIKRLMDIGAYRGLRHRRGLPVRGQRTKTNARTRKGPRKTVAGKKKATRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RS3_STRSV
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQKELADAAISTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINIIEIKRPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGADIARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: BOPA_BURM7
Sequence: MINVGAFVASARSGARVVVGGDARGPVVSAARLGMKERLFAFLAHVPLLKHCDAVRRYAEQVRMENRRSLEVFVLALSKRYGPEGAKAAFDYGARRDGAPLDQRRVRNMVSIAEHFHGTGDAKPLARQMVFRSWECRGLDHPGHASLTIKNQADADAGRHVYEHVSWWPNQRLGSKEHFDRIEPKTLDGYRIDKRSEISSATEQRLREGDAARRKILADGFKYANQDERHDALFFPRAGQKLDKDAEWGLSARKVYFPAIGFNHDRRDTDRPRAFVLFGLNEAAMLRDARTVKEGAKSGELKYRMISKKENCASMALRVLRAGGAEHFVPYTAAWISEDPNHAHAYALAVQARIDALNQRRADVERRCERLRDSASVRQAWRAFSEAGGASASPLAEDAGRGRASAHMRQARLDEHAREVERIGAYFAELSAGRSGKHRDRADADLADAMKRCAPSARDDVAALTRKASVLVETLGRHLDAPPPSDSSALRRLAAHAMIGRIEAFMAAAIAA
What is the function of this protein?
Plays a role in mediating bacterial evasion from the host autophagic pathway.
What are the official names of this protein?
Effector protein BopA.
What is the protein family that this protein belongs to?
Belongs to the BopA/IcsB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the bsa type III secretion system.
Protein: ASTB_MARN8
Sequence: MVKHAVEANFDGLVGPTHNYAGLSWGNVASKSNVNAVANPREAALQGLAKMKRLADRGYVQGILPPHERPHIPTLRALGFEGNERQILEAVAKADPTILAAVSSASCMWTANAATVSPSADTADHRVHFTPANLSAKFHRSIEHQVTGRSLKAIFGDESYFAHHPALPSVSHFGDEGAANHTRLCSRYGEPGVELFVYGQVAFNESAPAPGKYPARQTLEASRAIARLHGLTDRHAVFAQQNPAAIDAGVFHNDVIAVGNGNCLFYHEQAFLDEARVLADIQERLTGAELEAVRVSSTQVPIEDAVASYLFNSQLLNTADGMLLAVPGECREVASVSRYLDELVKADTPITAVEVFDVKQSMRNGGGPACLRLRVVLNDDELHAINRGVILTDALYERLTSWVEAHYRDQLSQQDLADPMLLEEVRKALDELTGILGLGSIYDFQL
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: FM521_PICST
Sequence: MSAFVLGSTGLVGLQILKVLDSSTAFKKVSTVSRRLPSVTSGKINSIEKKESEEWPAIIEKEAKDYSAFFSAFGTTRAAAGSADNFKKIDYGINYEAAKAAKAAGVETFVLVSTIGANAQSSFLYLQVKGQLEEDIIALKFPRTIILRPGILLGERETSKGLLNNLSVGVLKYLHGTPLTFLGNPIFGAEVAQIAVNAAQESFEKGDEPVVKFYEARELTELYKKL
What are the official names of this protein?
Protein FMP52-1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: RECO_AZOPC
Sequence: MLYKTKAITLYNINYNDNYSIVHVLTEEFGPVSYLTAKFKKQKTHLSKSFFHPLSLVELEVEHKNLREIQYIKEAKTYIPLVSLLNNPIKSSICIFLAEFISKALKEKQSDKLLFNYILQSIQVLEFIEKNYSNFHLVFTIRLSQFLGFYPNNTDYSKGMYFDMQNGIFVQQQPPHTHFVHSDDSWIVAKLLQMNYENMFHFQFTRNERKKIISQILEYYYLHLGGFSKIKSLAILHSVFD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RBL_GNEPA
Sequence: MSPKTETKASVGFQAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDLEPVPGEDNLFIAYVAYPLDLFEVGSVTNMFTSIVGNVFGYKALRALRLEDLRIPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEALNKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHGGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDAVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLVREGNEVIREASKWSAELAAACEVWKEIKFEFAPVDTV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPA14_YEAST
Sequence: MMKGSRRTGNNTATTLNTPVVIHATQLPQHVSTDEVLQFLESFIDEKENIIDSTTMNTISGNAADADAAAVANTSLNIDTNLSSSISQLKRIQRDFKGLPPAQDFSAAPIQVSTTEKKETSIGVSATGGKKTTFADE
What is the function of this protein?
DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I (Pol I) which synthesizes ribosomal RNA precursors.  RPA14 seems to play a role in the stability of subunits RPO26 and RPA43.  In vitro, the RPA14-RPA43 subcomplex binds single-stranded RNA.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA14, A14, DNA-directed RNA polymerase I 14 kDa polypeptide.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YIDD_DESAH
Sequence: MVKRSILLLIKVYQYFISPLTGPTCRFYPTCSQYAFEAVMIHGSLKGSCLAVRRILKCHPFHPGGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ECT2L_HUMAN
Sequence: MESFHTRFSAWTPFSNKSLNRQLFQERVALISHWFDLWTNKQRQEFLFAIFLRCTKSQLRFVQDWFSERMQVAKVDFSTVLPRFISLYIFSFLSPKDLCAAAQVSWPWKFLTEQDCLWMPKCVKFGWFLPYTPTDNEYGAWKRHYIACVSHLDWLTPREAAATYGTLNEPKTEDEELLERQREKCLRKRIWEKIALRKKELFKVRPPWVSGTCCSSVLKPRCQPRLSQTVRERVGLHEALEKQLVLTSLETLPKRSNISGSHSYPLLSKKNWHGVHKNDDRSSYALRPHFMLISSRIPAYEMVMESVKAGVVSVVYEHSVTLESLLYLIEKALDGQKAQSIGIFSDGDSREINLLQGYKIGVKNLLRPEVRDFWEKLGSYVATEEEGGHVDFFVPLGASEAGIEVLSQLSQLTGTFFTAPTGIATGSYQHILSDWLGSQWGKAPSSIYFCESKLQTWSSFTDFLEETLKTVRKQLYPFFKELQKSISGRMIGQFMFDTMGMTNILNNQDTAQALADGLMELSKEDSERNVVEDNSWDTKSRLSKNDLNFEALINLERILQKDSAEKRARVVRELLQSERKYVQILEIVRDVYVAPLKAALSSNRAILSAANIQIIFCDILQILSLNRQFLDNLRDRLQEWGPAHCVGEIVTKFGSQLNTYTNFFNNYPVILKTIEKCREMIPAFRTFLKRHDKTIVTKMLSLPELLLYPSRRFEEYLNLLYAVRLHTPAEHVDRGDLTTAIDQIKKYKGYIDQMKQNITMKDHLSDIQRIIWGCPTLSEVNRYLIRVQDVAQLHCCDEEISFSLRLYEHIHDLSLFLFNDALLVSSRGTSHTPFERTSKTTYQFIASVALHRLLIENIPDSKYVKNAFILQGPKYKWICATEIEDDKFLWLSVLRNAIKSSMEK
What is the function of this protein?
May act as a guanine nucleotide exchange factor (GEF).
What are the official names of this protein?
Epithelial cell-transforming sequence 2 oncogene-like, Lung-specific F-box and DH domain-containing protein, Putative guanine nucleotide exchange factor LFDH.
Protein: PSAA_GINBI
Sequence: VKIVVERDPIKTSFEKWAKPGHFSRTLAKGPNTTTWIWNLHADAHDFDSHTNDLEEISRKVFSAHFGQLAIILIWLSGMYFHGARFSNYEAWLSDPTRIKPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALIFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQLLDAGVDPKEIPLPHEFISNRDLVAQLYPSFAKGLTPFFALNWSEYSEFLTFRGGLNPVTGGLWLTDTAHHHLAIAILFLIAGHMYRTNWGIGHSLKEILEAHKGPFTGEGHKGIYEILTTSWHAQLALNLAMLGSLTIVVAHHMYSMPPYPYLAIDYGTQLSLFTHHMWIRGFLIVGAAAHAAIFMVRDYDPTIQYNNLLDRVLRHRDAIVSHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWIQNTHASAPSSTAPGAAASTSLTWGGGDLLAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDRGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIVQGRAVGVAHY
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PARC_ECO57
Sequence: MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL5_CLOAB
Sequence: MVPRLKEKYEKEVIPALMEKFQYKNIMEVPKLEKIVINMGVGEAKENQKVLESAVADMQLISGQKPILTRAKKSVANFKIRENMPIGCKVTLRKNKMFEFADKLMNVALPRVRDFRGVSSKSFDGRGNYALGIKEQLIFPEVEYDKIDKVRGMDVIFVTNAKTDEEARELLRFLGMPFAQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ITM2B_HUMAN
Sequence: MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAVETLICS
What is the function of this protein?
Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers.
What are the official names of this protein?
Integral membrane protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane protein BRI, Bri.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
[Integral membrane protein 2B]: Golgi apparatus membrane; Single-pass type II membrane protein. Note=Immature BRI2 (imBRI2) is cleaved by furin in the Golgi into mBRI2 and a Bri23 peptide. mBRI2 is transported to the plasma membrane and Bri23 peptide is secreted. SUBCELLULAR LOCATION: [BRI2, membrane form]: Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Mature BRI2 (mBRI2) needs to be transported from the endoplasmic reticulum compartment to the cell membrane in order to be able to inhibit APP processing. SUBCELLULAR LOCATION: [Bri23 peptide]: Secreted. Note=Detected in the cerebral spinal fluid (CSF). SUBCELLULAR LOCATION: [BRI2C, soluble form]: Secreted.
Protein: RL19_STRSY
Sequence: MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFEGVVISRKGQGISEMYTVRKISGGVGVERTFPIHTPRVDKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PETN_GLOC7
Sequence: MDILALGWVSVLALFTWSIAMVVWGRNGF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RHLB_ALIF1
Sequence: MKKTHITEQNFADLGLQPQVIDGLNAKGFIKCTPIQAKALPVLLAGQDIAGQAQTGTGKTLAFLTATFNHLLTTPAPEGRKITQPRAIIMAPTRELAIQIFNDAESLIASTGLKAALAYGGERYEKQQQVIEQGVDILIGTTGRIIDFYKQGHIDFKMIQAVVLDEADRMFDLGFIKDIRFIFRRMPAPTERLNMLFSATLSYRVQELAFEHMQEPEHVVVEPEQKTGHRIKEELFYPSNDHKMALLQTLIEEEWPDRAIIFANTKHKCESVWGHLAADKHRVGLLTGDVPQKKRERILEEFTQGNVDILVATDVAARGLHIPQVTHVFNFDLPNEAEDYVHRIGRTGRAGASGNSISFACEEYAINLPAIEEYIEHSIPQSDYDASALLEDLPAPLRLQRRPQQNRRNNNGQRQGGNRKHTRPRQPRNTQS
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SINA3_ARATH
Sequence: MDLDSMDCTSTMDVTDDEEIHQDRHSYASVSKHHHTNNNTTNVNAAASGLLPTTTSVHELLECPVCTNSMYPPIHQCHNGHTLCSTCKARVHNRCPTCRQELGDIRCLALEKVAESLELPCKHMSLGCPEIFPYYSKLKHETVCNFRPYSCPYAGSECSVTGDIPFLVAHLRDDHKVDMHSGCTFNHRYVKSNPREVENATWMLTVFHCFGQYFCLHFEAFQLGMAPVYMAFLRFMGDETEARNYNYSLEVGGYGRKLIWEGTPRSVRDSHRKVRDSHDGLIIQRNMALFFSGGDRKELKLRVTGRIWKEQQQSGEGGGACIPNLS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:32786047).  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:32786047).  It probably triggers the ubiquitin-mediated degradation of different substrates (PubMed:32786047).  Modulates directly the ubiquitination and proteasomal-dependent degradation of FREE1, a component of the ESCRT-I complex (PubMed:32786047, PubMed:32753431).  Modulates directly the ubiquitination and proteasomal-dependent degradation of ELC/VPS23A, a component of the ESCRT-I complex (PubMed:32753431).
What are the official names of this protein?
E3 ubiquitin-protein ligase SINAT3, RING-type E3 ubiquitin transferase SINAT3, Seven in absentia homolog 3.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
What are the subcellular locations of this protein?
Endosome, multivesicular body. Cytoplasmic vesicle, autophagosome.
Protein: GPA2_PEA
Sequence: MGLVCSRNRRYRDSDPEENAQAAEIERRIESETKAEKHIQKLLLLGAGESGKSTIFKQIKLLFQTGFDEAELRSYTPVIFANVYQTIKVLHDGAKELAQNDLNSAKYVISDESKDIGEKLSEIGSRLDYPHLTKDLAKEIETLWEDAAIQETYARGNELQVPDCTKYFMENLQRLSDANYVPTKGDVLYARVRTTGVVEIQFSPVGENKRSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDESKNRLMETKELFEWILKQPCFEKTSFMLFLNKFDIFEKKILNVPLNVCEWFKDYQPVSSGKQEIEHAYEFVKKKFEELYFQSSAPDRVDRVFKIYRTTALDQKVVKKTFKLVDETLRRRNLFEAGLL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-2 subunit, GP-alpha-2.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: TERE_ALCSP
Sequence: MAVSLVKGGNVSLTKEAPSMNVALVGLGWDTRVTDGQAFDLDASVFLVGENGKVLSDSHFVFYNNTTSPDGAVQHQGDNRTGEGDGDDEQVKIDLTKVAADVKKLVFAVTIHEADSRKQNFGMVSNSFMRVVNNDNGSEIARFDLSEDASTETAMIFGELYRHGAEWKFKAVGQGFAGGLAALATQHGINI
What is the function of this protein?
Not known; seems to contribute to the tellurium resistance (Ter) mechanism.
What are the official names of this protein?
Tellurium resistance protein TerE.
What is the protein family that this protein belongs to?
Belongs to the CAPAB/TerDEXZ family.
Protein: NDHK_MESVI
Sequence: MVIKSVGIESDKNSDTNERLINYNIEKPQVTQNVSNQLILTTLNDLYNWARLSSLWPLLYGTSCCFIEFACLLGSRFDFDRFGLVPRCSPRQADLIITAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAIIDAVIKLRKKVAQENLVERGKLAQTHRYHSIKHELTLSSPVYTGKYLNSSARQTPPRSLSEATGVPVNLIFEMTKKNAIK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.