PharMolix/UniProtQA huggingface dataset:
Protein: T170B_HUMAN
Sequence: MKAEGGDHSMINLSVQQVLSLWAHGTVLRNLTEMWYWIFLWALFSSLFVHGAAGVLMFVMLQRHRQGRVISVIAVSIGFLASVTGAMITSAAVAGIYRVAGKNMAPLEALVWGVGQTVLTLIISFSRILATL
What is the function of this protein?
Negatively regulates the canonical Wnt signaling in breast cancer cells.  Exerts an inhibitory effect on breast cancer growth by inhibiting CTNNB1 stabilization and nucleus translocation, which reduces the activity of Wnt targets (PubMed:29367600).
What are the official names of this protein?
Transmembrane protein 170B.
What is the protein family that this protein belongs to?
Belongs to the TMEM170 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MEPA_SALSV
Sequence: MKKTAIALLAWFVSSASLAATPWQKITHPVPGAAQSIGSFANGCIIGADTLPVQSDNYQVMRTDQRRYFGHPDLVMFIQRLSHQAQQRGLGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWSQAQLLRPQALDLVSRDGKHVVPSRWSSDIASLIKLAAQDNDVTRIFVNPAIKQQLCLDAGNDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVL
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GPMB_ECO24
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: ZFP57_HUMAN
Sequence: MAAGEPRSLLFFQKPVTFEDVAVNFTQEEWDCLDASQRVLYQDVMSETFKNLTSVARIFLHKPELITKLEQEEEQWRETRVLQASQAGPPFFCYTCGKCFSRRSYLYSHQFVHNPKLTNSCSQCGKLFRSPKSLSYHRRMHLGERPFCCTLCDKTYCDASGLSRHRRVHLGYRPHSCSVCGKSFRDQSELKRHQKIHQNQEPVDGNQECTLRIPGTQAEFQTPIARSQRSIQGLLDVNHAPVARSQEPIFRTEGPMAQNQASVLKNQAPVTRTQAPITGTLCQDARSNSHPVKPSRLNVFCCPHCSLTFSKKSYLSRHQKAHLTEPPNYCFHCSKSFSSFSRLVRHQQTHWKQKSYLCPICDLSFGEKEGLMDHWRGYKGKDLCQSSHHKCRVILGQWLGFSHDVPTMAGEEWKHGGDQSPPRIHTPRRRGLREKACKGDKTKEAVSILKHK
What is the function of this protein?
Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation.  Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs) (PubMed:18622393, PubMed:30602440).  Acts together with ZNF445, but ZNF445 seems to be the major factor in human early embryonic imprinting maintenance.  In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance (PubMed:30602440).  Required for the establishment of maternal methylation imprints at SNRPN locus.  Acts as a transcriptional repressor in Schwann cells.  Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (By similarity).
What are the official names of this protein?
Zinc finger protein 57 homolog, Zfp-57, Zinc finger protein 698.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZFP57 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Binds various differentially methylated regions (DMR).
Protein: SELTA_DANRE
Sequence: MRWLPFSALLLWALCLHSASADNNGVKKMKMQFATGPLLKFQICVSUGYKRVFEEYTQALYQRYPDIRIEGENYLPLPLYRHIASFLSMFKLLLIGVIILGKDPFALCGMQAPGIWVWSQENKIYACMMVFFFSNMIENQCMSTGAFEITLNDVPVWSKLESGHLPSMQQLVQILENEMKMSMHMDTLPPHQS
What is the function of this protein?
Selenoprotein with thioredoxin reductase-like oxidoreductase activity.
What are the official names of this protein?
Thioredoxin reductase-like selenoprotein T1a.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. Selenoprotein T subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: 1MMP_ARATH
Sequence: MSRNLIYRRNRALCFVLILFCFPYRFGARNTPEAEQSTAKATQIIHVSNSTWHDFSRLVDVQIGSHVSGVSELKRYLHRFGYVNDGSEIFSDVFDGPLESAISLYQENLGLPITGRLDTSTVTLMSLPRCGVSDTHMTINNDFLHTTAHYTYFNGKPKWNRDTLTYAISKTHKLDYLTSEDVKTVFRRAFSQWSSVIPVSFEEVDDFTTADLKIGFYAGDHGDGLPFDGVLGTLAHAFAPENGRLHLDAAETWIVDDDLKGSSEVAVDLESVATHEIGHLLGLGHSSQESAVMYPSLRPRTKKVDLTVDDVAGVLKLYGPNPKLRLDSLTQSEDSIKNGTVSHRFLSGNFIGYVLLVVGLILFL
What is the function of this protein?
Matrix metalloproteinases (MMPs) or matrixins may play a role in the degradation and remodeling of the extracellular matrix (ECM) during development or in response to stresses (PubMed:10574937).  Can cleave myelin basic protein as well as fluorigenic peptide substrates, McaPLANvaDpaAR-NH(2) and McaPChaGNvaHADpa-NH(2) 4-fold more efficiently than McaPLGLDpaAR-NH(2) (QF24) (PubMed:10574937).  Active on myelin basic protein (MBP) and, to some extent, on McaPLGLDpaAR-NH(2) (QF24) and beta-casein (PubMed:24156403).
What are the official names of this protein?
Metalloendoproteinase 1-MMP, At1-MMP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family. Matrix metalloproteinases (MMPs) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.
Protein: RS16_CLOBJ
Sequence: MAVKIRLKRMGAKKAPFYRVVVADSRSPRDGRFVEEIGYYNPITEPSTIKLDEEKVQKWIKNGAQPTDTVKKLIEKAGISVK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: XYLA_STROL
Sequence: MSYQPTPEDRFTFGLWTVGWQGRDPFGDATRPALDPVETVQRLAELGAHGVTFHDDDLIPFGSSDTERESHIKRFRQALDATGMTVPMATTNLFTHPVFKDGGFTANDRDVRRYALRKTIRNIDLAVELGAKTYVAWGGREGAESGAAKDVRVALDRMKEAFDLLGEYVTSQGYDTRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQSGIKYDQDLRFGAGDLRAAFWLVDLLESAGYEGPRHFDFKPPRTEDIDGVWASAAGCMRNYLILKERAAAFRADPEVQEALRASRLDELAQPTAADGVQELLADRTAFEDFDVDAAAARGMAFERLDQLAMDHLLGAR
What is the function of this protein?
Involved in D-xylose catabolism.
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_STRKA
Sequence: MSSSITAPEGIINPPIDELLEATDSKYSLVIYAAKRARQINAYYSQLGEGLLEYVGPLVDTHVHEKPLSIALREINAGLLTSEAIEGPAQ
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.  Required for kasugamycin production and aerial mycelium formation in S. kasugaensis and responsible for pleiotropy.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: LAC2_AGABI
Sequence: MRFSNAFVLVAACISSVLADTKTFNFDLVNTRLAPDGFERDTVVINGEFPGTLVQVNKGDSVRIPVNNKLTSSTMRRSVSIHWHGFFQARTSGQDGPAFVNQCPQPPNTTFTYEFSVADESGTFWYHSHLSTQYCDGLRGAFVVYDPEDPLGHLYDVDDETTVITLAEWYHVLAPDINNEFFSSGIIPVQDSGLINGKGRFNGGPETPFAVVNVEQGKRYRFRVIAISCRPFFTFSVDNHNLTFMEADSVEHDPVEIQNVDIYAAQRVSVILNANQPVDNYWMRAPMTGGNPDRNPNLNISLTLAILRYKGAPEVEPTTVNVPGHKLLDQEMHPIAQEGPGKLGDGPPDKHITLNIAQPNAPFFDINGISYISPTVPVLLQILSGAKRPEDVLPSEQIFFVPKNSLIEVNIPGEGAHPFHLHGHNFDVVLASNDDTFNFVNPPRRDVYPINGGNTTFRFFTDNPGAWFLHCHIDWHLEAGLAIVFAEAPEDNVSGPQSQITPQDWLDLCPEYNAIEPEFQ
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-2, Benzenediol:oxygen oxidoreductase 2, Diphenol oxidase 2, Laccase II, Urishiol oxidase 2.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: TTL10_HUMAN
Sequence: MDHSCTRFIHRRGPPTRTRAGFKRGKRPRIQQRPRARVSGTIPASRLHPAPASQPGPCPAPGHCPVGPAHERPMGSSQEEGLRCQPSQPDHDADGHCGPDLEGAERASATPGPPGLLNSHRPADSDDTNAAGPSAALLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQRIHDSRRDDYTLKWCEVKSRDSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGVQARLEKDAAAPALEDLPWTSPGYLRPQRVLRMEEFFPETYRLDLKHEREAFFTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIFFGHGYARLTLSLYDPHSSDLGGHLTNQFMQKKSPLYMLLKEHTVWSMEHLNRYISDTFWKARGLAKDWVFTTLKKRMQQIMAHCFLAAKPKLDCKLGYFDLIGCDFLIDDNFKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLVLETFRKSLRGQKMLPLLSQRRFVLLHNGEADPRPHLGGSCSLRRWPPLPTRQAKSSGPPMPHAPDQPGARRPAPPPLVPQRPRPPGPDLDSAHDGEPQAPGTEQSGTGNRHPAQEPSPGTAKEEREEPENARP
What is the function of this protein?
Inactive polyglycylase.
What are the official names of this protein?
Inactive polyglycylase TTLL10, Tubulin--tyrosine ligase-like protein 10.
Protein: CYB_NOMLE
Sequence: MTPLRKTNPLMKLINHSLVDLPAPSNISMWWNLGSLLGTCLVLQIVTGLFLAMHYTPDASMAFSSVAHITRDVNYGWVIRYLHANGASMFFICLFLHIGRGLYYGSFLYLETWNIGIILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAVPYIGTDLVQWVWGGYSVDNATLTRFFTFHFILPFIITALVALHLLFLHETGSNNPLGISSQPDKITFHPYYTTKDILGLFLLLLTLMSLVLFSPDLLGDPDNYIQANPLSTPPHIKPEWYFLFAYAILRSVPNKLGGVLALLLSILILMTIPMLHTAKQQSMMFRPLSQLTYWLWAANLLTLTWIGGQPVSYPFITIGQVTSVLYFITILILVPTASLIENKMLKWT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DSBD_PASMU
Sequence: MKKIFFIFFLIWTSLSVNAGVFDKKNAFLKAEQAFVFTESQQNDRLSLNWDIASGYYLYKKSLEIKGENGQLFIPQLPLAEIHQDDFFGDVEIYRHQLTFSLPFTQLSATKQVEITYQGCTEGFCYPPETRVIALTSLERESGQISSAVLKEESVLSELPLAEQDRLAAKLIESKYAVFWFFLFGLGLAFTPCVLPMLPLLSAIVIGREQRPSTAKAFGLSVVYVQGMALTYTLLGLIVAAIGLPFQVALQSPYVLLTLSAIFVLLALSMFGLFTLQLPVSLQTKLTQYSQQQKSGVFGGVFVMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAITLYLLALGMGLPLIFITVFGNNILPKSGNWMIQVKNAFGFVLLALPIFLISRVFPEIEMPLWFSLAFAFSLWLLYQFRNNKGVWVFTFILGVMGYLYYSYAMNRHTPAHQTTSLSQFERITSYAQLQQVLSKNPNSLAMLDLYADWCVACKEFETHTFSDVAVQKAFTDVLLLQVDMTKNSEANRELMQKLHVIGLPTLIFFNQQGQEIEGSRITGFMQASPFVDWLQKMKSIQPISQ
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_ECO55
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: KAR5_DEBHA
Sequence: MDCVNISWFLITLFAAIATSTMHDGENNNVGKMLQEPTYLQSEMIESIMSRHLESFSLTESDFEDIIFMKPRSKCVKDALKDIIPECMRLGVDSIEPGLQKKAAIQLSICEFENSKVTYPSSCYNMINDNDFDSCIFDIERAPQYWTTFSGYYREITKICYEESLPFEKEQIISLYSNITKLYSKMFQDLNDSYKDSTHIQQMMKNEFKELQRMMKVILDQNEKTSEEVKEKYEEFSEQYSSMLSTSLEISKKFSLGTENLVEDMANNIKYLDFELSRISIAIEDLDFETKLTDMKNSVLDDVRNLSDESISLLDSILTNLESLDILSQDAQNITNGISQSLKKNEVLSNNMNNALIETDTQLHEHNEVIRFEFEETISYLSQFSDQAIDNAIRDTSEEITKHVATFIDSINLRLEETTTKLEEVIYNIDDLSDKVGNASSYLIEGLNLLTSNGIMDALLLTYNNVASGLESGFGMLTTLKSDIFKIVRFITACILFAILFIWSMNRLFSQNRTKHTTLSSISPIGILNFRRIFRFLTNLALWLSVMGGTLLAVIVTNFLIQLKVYISKLSTND
What is the function of this protein?
Required for nuclear membrane fusion during karyogamy.
What are the official names of this protein?
Nuclear fusion protein KAR5, Karyogamy protein 5.
What is the protein family that this protein belongs to?
Belongs to the KAR5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: GLGA_XANOP
Sequence: MLPALKKGGRPRDALGRFIRHHERLPVSLADTRGVLFVVSEMADFIKAGGLGDVAAALPRALRHRYDVRVLIPGYRAVLERAGKVEIVGRVLAHAALPACDIGRIVQSDGLPIYILLSRELFERDGSPYVSTSGSEFEDNAIRFATLSHAAADIAAGHAGLGWKPRLLHLNDWPCALAAGYVRWSGGTTPCLLTIHNLAYQGLVPYSMAGALGIPAERVAELEFYGQMSFLRGGIVNADHVNTVSVSYAKQITGPAQGCGLDRLLAGRAAKGVLTGIVNGIDASWDPRTDEYLDSHFSVNQWQGRQDNAAQVRKAFGLRESTGPLFAVVSRLVHQKGLDLICEVAPQIVAAGGQIAVIGGGEPDIERQVAELTRRYPGQVGAFIGFEEGLARRMFAGADFLLMPSRFEPCGLSQMYAQRFGCLPIAHATGGLIDTVDDGVTGFLFQHASVEALRRCLERAFRTFRLPGLLAAMRRAAMLRPSGWDVAGNKYLSLYERTAAIAPALATVS
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: SYN_DESVV
Sequence: MQRTQIVDALAATAPQPVIRLCGWVRTRRDAKGFSFLEINDGSCLANIQAIVDEGIPAYANIGAVSTGAAVDITGELVESPGKGQKWEVRVQTLTLLGAADAETYPLQKKRHSDEFLRSIAHLRARTNKYGAAFRIRSEAAFAIHEFYRERGFFYVHTPILTGSDCEGAGEMFRVTTLPVEGSPTPASGNRYENDFFGKECNLTVSGQLEAETLALGLGKVYTFGPTFRAENSNTPRHAAEFWMIEPEVAFADLEEDMNLAEDMTRTVVRRILDRCAADLDLFNRFVDTTLVERLRQIADEPFARCSYTEAIELLLKSGKKFEYPVSFGLDLQTEHERYLAEEHFGKPVIVYNYPKEIKAFYMRLNDDGRTVAAMDVLVPRIGELIGGSQREERLDVLEARINEMGQNLEDYWWYLDLRRFGSVPHAGFGMGFERLLMLLTGITNIRDVIPFPRTPGNLEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC6A8_RAT
Sequence: MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPSKGDGPAGLGAPSSRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYKPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
What is the function of this protein?
Creatine:sodium symporter which mediates the uptake of creatine (PubMed:12433955, PubMed:8297374, PubMed:15702372, PubMed:32115505).  Plays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity).
What are the official names of this protein?
Sodium- and chloride-dependent creatine transporter 1, CHOT1, CT1, Creatine transporter 1, Solute carrier family 6 member 8.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HCP_ECO24
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMANLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_METPP
Sequence: MRTTYCGLVSEMLLGQTVTLMGWAHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKAAEGVRNEFCLKIVGKVRARPAGTENANLVSGKVELLCHELEVLNPSVTPPFQLDDDNLSETTRLTHRVLDLRRPAMQKNLILRYRVAMEVRKFLDANGFIDIETPMLTKSTPEGARDYLVPSRVNEGMFFALPQSPQLFKQLLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDIETSFLDEEEIRGMFEGMIRTVFRAVMNVELPGYPVMKYAEAMHRFGSDKPDLRVKMEFTELTEVMKDVDFKVFSAPAQAKGGRVVALRVPGGGEMSRSEIDGYTEFVKIYGAKGLAWIKVNDASKGREGLQSPIVKNLHDAAIAEIIARSGARNGDLLFFGADKAKVVNDAIGALRVKIGHSDFGKSGGLFEDKWAPLWVVDFPMFEHDEEGDRWAAVHNPFTAPKDGHEDLMDTDPGKCIAKAYDMVLNGWELGGGSVRIHRAEVQSKVFSALKIGPDEAQLKFGFLLDALQYGAPPHGGLAFGLDRLVTLMTKADSIRDVIAFPKTQRAQDLLTHAPSPVDEKQLRELHIRLRNPAAGQSGV
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T15BB_XENLA
Sequence: MWAWALLPICLTVWATGGIWIVYAMSVSNGSVNLSDGFPYISVSGTYPPQSCVFGQVLNVGAMLAVWISVIRFQQIRDYNCHSVLNSVSLATGILCALGTSIVGNFQQSNQLQTHLAGAFLAFIIGNVYFWMQTALTYMVKPKHGGCYIGPIRFCLSIACTALIVAMAVFLKMNMKSVSAICEWIVAMILFLLYGLFAVDFWHLDGHFFHVKKRRTVIPNEMEVSTVTLSI
What is the function of this protein?
Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux (By similarity).  Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner (By similarity).  May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival (By similarity).
What are the official names of this protein?
Modulator of macroautophagy TMEM150B-B, Transmembrane protein 150B-B.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein.
Protein: PSD_PELPD
Sequence: MKNQNTPIAFEGFPFIAGFAALTLLTALSAGKLCSAILYGFSALFALLTLFSLYFFRNPQRTPPADERAVVAPADGTVIVVDRVPVTPLGHEALKISIFMSVFNVHVNRVPFSGRVVELTHTPGKFFDVRDSRSSCENERSTIVLETVSGLRMAFVQVAGLIARRIVCYARNGEMLERGKRYGLIRFGSRLDVYLPPDVQPLVKLGDKTIAGETVLGRLG
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RTC5_AJECN
Sequence: MGGALSTDDPEQRASSVEELNQRLAHRFAAKCFEPLELTHLKENFFSRALDQHGIRYWNEEILSEFLGIPDGAGSAAAATSDGSLDAGPVIFRMVSYLGAFPFQNTMAPTVLTFESMVKVVVLLTERYGKVLKRGKKDRIKLLFGSLADVGRRDIITQLKEATEDSLESIGPFDPKSASPSTHNTGFLVDQPLNDEDEEDDDDLAIAALESLDAIEVFKHDQRIDKTVYESKISLTTFRRLLTLLLVTAPLRPLGRVSKFTTGLSKPSLDAVHEQVDSILAALEPGEASDGIGYKSFSKLVSTSLPYLFDPLTPLFEHLLFSKNLDLSRKRDSQTTNGLTNKPVPTPPSTPPISPPLSPVISTGGFDSRILNPAVLSHLSFFVSTNVHIPNIFRNRTHLHPVFSSTEHGESLTSFSHHVMTWQAPSILLVRGAVVSESSEEQLTTIGAYLPQPWKQTSSYSSRRSSEVPDPSTLPCLFELSPVHTVLQGSPSFSSLKPNMPVSHFSTKTGIAIGCVIPPSSRKSLGSDLHPKPAGGGSLLIDSALENATFIVSNGLNGPGVFLPPGISPVLSSTSLTASVASMSSSNQNITKSISIYNLEVWGIIPSTSLATQLDGSGSPIEKRDAISLQRAQWDFEAREAERRQAINMKVGGGEADVPTGRALLEMAGIIGDSYYSGHHRH
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_STRT1
Sequence: MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYNAFEVKTYFITQSGDFIKTQEFIETPGDDEKLMTNDTVEASQAIKPSDIYEEDAVVFPVLHGPMGEDGSIQGFLETLKLPYVGTNVLSSSVAMDKIMTKRILEVAGVPQVAYTVYIEGEDLEAAVAETLEKLTFPVFVKPANMGSSVGISKAENESELRSAIDLALKYDSRILIEQGVVAREIEVGILGNTTVKTTDPGEVVKDVAFYDYQAKYIDNKITMDIPARVPVEVMTQMRAYAAKAFRALGGCGLARCDFFLTEDGAIYLNELNTMPGFTQWSMYPLLWENMGLSYSDIIKELVVLGQEMFDKRESHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_SULDN
Sequence: MLEGIIRESIGKKGTKALRRDGYLIANIYGKGLQNLHAAFKENEYIRTVRNKETLSFPIKVDSKEMNVVVQAYEAHPVTGKLLHVDLMVAQPNVVTHYHVPVVTEGDAIGLKNKGLIHISKPRLRVKATIENTPNSIVVDVTKMDVGDAKMVRDIAKIANVTFTDADRVSVLSVIKAK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: FTHS_AERHH
Sequence: MLSDIEISRQSPRLPIHALAERLAIPSHQLHPYGHYKGKLSLELLKSLPKPAGKLVLVSAITPTPLGEGKTVTTLGLSMGLNHIGQPSIATIRQPSLGPVFGVKGGAAGGGHAQVVPMEEMNLHLTGDFHALTAAHNLAAAALDARLFHERKLGDQFSARTGLQRLDIDADNILWPRTLDMNDRALRHLTIGQGNAADGVERSDRFVITAASELMAILALASDLKDLRQRIGRIQLARDLRGKPITAEQLEVAGAMTVLLKEALQPTLMQTTEQTSVLVHAGPFANIAHGNSSVIADRMALGLTDYVVTEAGFGSDMGLEKFFNIKHRQSGITPACVVLVATVRGLKANSGLLDIRPGQPLPESLLREDLPTLEQGCANLGWHIANARRYGVPVVVAINRFPTDSEAELALLARAALRAGACGSAISSAFTQGGAGASELAQAVVAACEQPGKVKLLYPDQASLGAKLATLVECGYGGRGVQLSDKARQQLAQLSAEGWDHLPVCVAKTPLSISHDPALKGVPTDFEVPIEEVKLCAGAGFVYALAGPIMTMPGLGSLPAYRHIDIDDNGEIVGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: ATPF_ECOL6
Sequence: MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIVAQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.