PharMolix/UniProtQA huggingface dataset:
Protein: GCSH_ALTMD
Sequence: MSNIPTDLRYAATHEWVRPEGDGVFTVGISEHAQGLLGDMVFVELPDVGDAVSTGDDICVAESVKAASDVYAPISGEVVEVNEDLEDSPELVNSDPYGDGWLFKIKADDAAEVEGLLDAEGYENSIDEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: NUSB_CROS8
Sequence: MKPAARRRARECAVQALYSWQLSHNDIADVEYQFLAEQDVKDVDVMYFRELLSGVATNSGYLDGLMKPYLSRQLEELGQVEKAVLRIALFELSKRDDVPYKVAINEAIELAKVFGAEDSHKFVNGVLDKAAPHIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HEMA_I60A0
Sequence: MAIIYLILLFTAVRGDQICIGYHANNSTETVDTILERNVTVTHAKDILEKTHNGKLCKLNGIPPLELGDCSIAGWLLGNPECDRLLSVPEWSYIMEKENPRNGLCYPGNFNDYEELKHLLSSVKHFEKVKILPKDRWTQHTTTGGSQACAVSGNPSFFRNMVWLTEKESNYPVAKGSYNNTSGEQMLIIWGVHHPIDEKEQRTLYQNVGTYVSVGTSTLNKRSTPEIATRPKVNGLGSRMEFSWTLLDMWDTITFESTGNLIAPEYGFKISKRGSSGIMKTEGTLENCETKCQTPLGAINTTLPFHNVHPLTIGECPKYVKSEKLVLATGLRNVPQIES
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore (By similarity).
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts (By similarity).
Protein: KHSE_CUTAK
Sequence: MDNSVRVRVPATSANLGPGYDCIGLALDLWDEVSVGVLDRPGVMIDVTGEGADTVPHDESHLVMATLRQGLVELGYPHPDAGLHLTAINSIPQSRGLGSSAAAVVSGLALAWGLARPGFPLDRSALLTMAAAIEGHPDNAAPAILGGAQLAWLDGEAVNHIGLTVNPSIVFRVYVPDRLVPTALARQVLPEQVDRVDAVHQVLAASLLVTALTTSPEHLLAATQDWIHQPYRRALMPESAALTDRLRGRGVATVISGAGPTVLALGSRDQLEKVSDVDTAGFVAHDLVLGEGVHFF
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2381_LEPIN
Sequence: MSKLKKRKGDEGESIASNFLISLDHEILKRNYRFLHCEIDIISVKEEVLYFSEVKFWKEFKFFDPRFTFNLAKQTKMRKAAKGFLAENLSFQNHFVSFCLVSVNEKKGCKYYLDLF
What are the official names of this protein?
UPF0102 protein LA_2381.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: TNAA_HAEIF
Sequence: MENFKHLPEPFRIRVIEPVKRTTREYREQAILKSGMNPFLLDSEDIFIDLLTDSGTGAVTQDMQAAMLRGDEAYSGSRSYYALAKAVKDIFGYEYTIPTHQGRGAEQIYIPVLIAKREREKGLDRSKMVVFSNYFFDTTQGHSQINGATVRNVYIKEAFDTTAKHPFKGNFDLEKLEKGIQEAGAHNVPYIVCTITCNSAGGQPVSIANLKGMYEIARKYDIPVIMDSARFAENAYFVQQREEAYKDWTIEQITYESYRYADGLAMSAKKDAMVPMGGILAFKDKSMEEVYHECRTLCVVQEGFPTYGGLEGGAMERLAVGLHDGMRQEWLAYRIAQIEYLVAGLEKIGVLCQQPGGHAAFVDAGKLLPHIPADQFPAQALSCELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTVPRATYTQTHMDFIIEAFQKVKENAENIKGLTFTYEPKVLRHFTARLKEVE
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: RS20_RICPR
Sequence: MANHSSAKKVVRQTVKRTLINKKRSSAIKTFIKKVIHEISRGNKEDANLALSIAQSKIMQGVKKNIIKLNTASRKIRRLSKQIKNLYKSE
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SILU_RHIPU
Sequence: ACLPNSCVSKGCCCGBSGYWCRQCGIKYTC
What is the function of this protein?
Sillucin is an antimicrobial agent produced by the thermophilic fungus Rhizomucor pusillus in liquid culture; it is effective against Gram-positive bacteria at the level of RNA metabolism.
What are the official names of this protein?
Sillucin.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_CUPMC
Sequence: MAITKDDILEAVGAMSVMELNDLVKAFEEKFGVSAAAMAVAAAPGAGGAAAAEEKTEFNVILAEVGSNKVGVIKAVREITGLGLKEAKDLVDGAPKPVKEGVDKATADDAKKKLEDAGAKVDVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RHBG_MOUSE
Sequence: MARVPRHRRLVLPLLCLLFQGATALLFAIFVRYNHETDAALWHWGNHSNVDNEFYFRYPSFQDVHVMVFVGFGFLMVFLQRYGFSSVGFTFLVASLTLQWATLLQGFLHSFHGGHIHVGVESLINADFCAGAVLISFGAVLGKTGPAQLLLMALLEAVLFSVNEFILLSLLGVRDAGGSMTIHTFGAYFGLFLSWVLYRSQLEKSRHRQSSVYNSDLFAMIGTIFLWVFWPSFNSAPTALGDGQHRTVVNTYYSLTASTLSTFALSALVSGDGRLDMVHVQNAALAGGVVVGTSSEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESRFKLQDTCGVHNLHGMPGVLGAILGVVVAALATHEAYGDGLQSVFPLIAKGQRSATSQAVYQLFGMFVTLVFASVGGSLGGLLLRLPFLDSPPDSQCFEDQVYWEVPGEQETETQRPLRGGESDTRA
What is the function of this protein?
Ammonium transporter involved in the maintenance of acid-base homeostasis.  Transports ammonium and its related derivative methylammonium across the basolateral plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism.  May transport either NH4(+) or NH3 ammonia species predominantly mediating an electrogenic NH4(+) transport (PubMed:15353405, PubMed:16131648, PubMed:20592240, PubMed:27681563) (By similarity).  May act as a CO2 channel providing for renal acid secretion (By similarity).
What are the official names of this protein?
Ammonium transporter Rh type B, Rhesus blood group family type B glycoprotein, Rh family type B glycoprotein, Rh type B glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: PHOB_ECO57
Sequence: MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEFKLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTVRGTGYRFSTRF
What is the function of this protein?
This protein is a positive regulator for the phosphate regulon.  Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity).
What are the official names of this protein?
Phosphate regulon transcriptional regulatory protein PhoB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSQ_ALIF1
Sequence: MIKAVKMNTSFDKEKVRKHLPGAIFLSLVVITSLWLVISTISWMTDEDRLPLSHMIIQGQLKHITADDIREAIDSMDSIGTFMTQDVNKLQDALLSLPWIAQVSVRKQWPETIKVFVVEHQPEATWNNRVIVNPEGVVFNAPMSDLREPKPALFGPETSSKDVLDFWHQLQKQFEPIHVTVHSVALTERLSWQVVLDNGIRLELGRDSREERVERFIALYKQLESKKDSIDYIDLRYDTGAAVGWKSDDVENKEEN
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: LEP_RICFE
Sequence: MQTDNTKSNTNKTAKQEWGSFAFVICIALLIRILIMEPFTVPTGSMKATILENDYIFSTKYSYGYSNYSLSFFDFIPLFKGRIFAREPERGDIVVFRPPNDMNVRYIKRLIGLPGDKIQLIDDVIYINDKKIERTEVGTYISEEGIKYLKFKETLPNGRTYFSYKLAPIFGVIYNDRYGNTDVFYVPEGKYFFLGDNRDQSNDSRVNLGFVPFENFIAKAQFIWLSTKITWWDNDIGVINLVLKLKPWIESVRLNRIFRNLYSTDE
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: HCY2E_RAPVE
Sequence: DDQGHTHRNLVRKSVRNLSPAERRSLVHALKSLQEDSSADGFQSLASFHAQPPLCPYPEANKRFACCVHGMATFPEWHRLYTVQFEDALRRHGSVVGIPYWDTVVPQEDLPAFFNDEIWDDPLFHANFTNPFNGADIDFNHQKIARDINVDKLFKEGPKGYDTWSFKQYIYALEQEDYCDFEVQFEIAHNAIHAWVGGTEEYSMGHLHYASYDPVFILHHSNTDRLFALWQELQKFRGHDPNEVNCALEMMREPLKPFSFGAPYNLNPTTKEHSKPEDTFDYKGHFHYEYDHLELQGMNVQRLHDYINQQKERDRVFAGFLLEGIGTSAHLDFSICKIDGECTHAGYFDVLGGSLETPWQFDRLYKYEITDVLESKGLDVHDVFDIKITQTSWDNEDISTDRFPPPSVIYVPK
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin type 2 unit e, RtH2-e.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ISPH_CLOTE
Sequence: MSIILAKKSGFCYGVKRAVDTCLKIKQNYPDKIIYTLGPLIHNNDVVDFLKTKNIFSIGYENIDTLKEGDIIILRSHGVTLETIQKLKEKKLNIIDATCPYVSNIQKKAQKYYKEGYSILIVGDKNHPEVIGINGWCNNSAIICRKAEEIEDLPKKICVVSQTTEKKEHWISVLSKVVNECREVVAFNTICNATEVRQLSAEDLSKEVDFMIVIGSKSSSNTTKLYEICKNNCSNTIHIENAGELPDYISNKYSKIGVTAGASTPDWIIKEAIFKMSNKNLNEQLEYMENNDIQISIGQEVEGEIVSIVSSNEAYVNIGYKSDAILLLSEVTKDNDEDINNFVKKGDIIKGKIIKLGSENKPPVISVIELNRENAYVELKEAFENKEKVVVKVKEDVNGGLISIYKNIVRVFIPASHVELRHVDDLSIYKGCELTVNIIEFEEGRNNTRIVASRRDLLKEEQSKVEEETWSSLEKDTIKEGEVRRLTDFGAFVNINGVDGLLHVSEISWGRVEKPSDMLKVGDKIKVYIKDIDKDKKKLALSIKDLTKDPWKDVEVKYPVGNIVLGTVVRFASFGAFVELEPGVDGLIHISQISHKRVDRVEDELSIGEQVKAKIVEVDGEKRKIGLSIKEVNDI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the IspH family.
Protein: RK2_TOXGO
Sequence: MILTFIKIKKYRIKYLIIKKQKAFGRNNLGFITCRAKGGGIKRNLYKILDSNFANYGMSFSSAFYVNIIYDSFRRIFLAVYFIINSIIKNIYRYFLLTKNLKIGSQINFGFKAPLKIGNALPLYKILLGSFIYNIEIRYKGKGSLVKNANHNAIILMIGDIYVTVKLPSGEIKLLLKNLFCILGQLEIRRKVNKNIKKHAGFNRKLSIRPKIRGAAMNAVDHPHGGGEGKASVGFKFARTLWGKAFKGIKTRKKNKHLSRFILQHRL
What are the official names of this protein?
50S ribosomal protein L2, apicoplast.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, apicoplast.
Protein: PLPL5_HUMAN
Sequence: MGFLEEEGRWNLSFSGAGYLGAHHVGATECLRQRAPRLLQGARRIYGSSSGALNAVSIVCGKSVDFCCSHLLGMVGQLERLSLSILHPAYAPIEHVKQQLQDALPPDAHVLASQRLGISLTRWPDGRNFLVTDFATCDELIQALVCTLYFPFYCGLIPPEFRGERYIDGALSNNLPFADCPSTITVSPFHGTVDICPQSTSPNLHELNVFNFSFQISTENFFLGLICLIPPSLEVVADNCRQGYLDALRFLERRGLTKEPVLWTLVSKEPPAPADGNWDAGCDQRWKGGLSLNWKVPHVQVKDVPNFEQLSPELEAALKKACTRDPSRWARFWHSGPGQVLTYLLLPCTLPFEYIYFRSRRLVVWLPDVPADLWWMQGLLRNMALEVFSRTKAQLLGPISPPATRVLETSPLQPQIAPHREELGPTHQA
What is the function of this protein?
Has abundant triacylglycerol lipase activity.
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein 5, GS2-like protein.
Protein: CRTM_STAA8
Sequence: MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFDNERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFQDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVDKRKKAKLFHEINSKYHRI
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes the head-to-head condensation of two molecules of farnesyl diphosphate (FPP) into the colorless C(30) carotenoid 4,4'-diapophytoene (dehydrosqualene).
What are the official names of this protein?
4,4'-diapophytoene synthase, DAP synthase, C30 carotenoid synthase, Dehydrosqualene synthase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family. CrtM subfamily.
Protein: ARLY_BURL3
Sequence: MTSQLHKKGEAWSARFSEPMSELVKRYTSSVFFDKRLALVDIAGSLAHANMLAAQKIISADDLAAIERGMAQIKGEIERGEFEWQLDLEDVHLNIEARLTALIGDAGKRLHTGRSRNDQVATDIRLWLRGEIDRIGGLLNDLRGALLDLAEQNADTIMPGFTHLQVAQPVTFGHHLLAYVEMFSRDAERMRDCRTRVNRLPLGAAALAGTSYPIDRHAVAKTLGFDGICANSLDAVSDRDFAIEFTAASALVMTHVSRFSEELVLWMSPRVGFIDIADRFCTGSSIMPQKKNPDVPELARGKTGRVNGHLMALLTLMKGQPLAYNKDNQEDKEPLFDTVDTVADTLRIFAEMVAGITVKPDAMRAAALQGFSTATDLADYLVKRGLPFRDAHEAVAHAVKVCDDRGIDLADLTLDEMKQELPNVAHLIGEDVFGYLTLEGSVASRNHPGGTAPDQVRAAVKAARAALGQ
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSL41_DICDI
Sequence: MTLFSSISSISNPMTSSKSSISSFGSGTSMGSNTVACGGGCGGSGGILGLGLGLGLGLDLTGGSRSRGACGGNGGNRGNGNGGMGGGNGPCCGGCCCGI
What are the official names of this protein?
HssA/B-like protein 41.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: ATPE_WIGBR
Sequence: MNNKFYQLTVISAENFIFSNLVKKSNITGSEGNLGILPGHAPLITKIKPGLIHIISSKNIEEYIYLSGGILEINSNVVTVLADTAIRGKEIDEKKAIESKKNAEELILKSKERHEYIRAVIELSKAIAKLRVCKLSNK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VE6_HPV41
Sequence: MASTSGVGSVGPASCCETQKPHTIRELCLAQQITYPCIQLCCHYCYKILSVLDIYAFDQSCLYLSWGEGGPTGICSQCTRVLARLEFTARHEVSCAASRLPHFIGQSLSDLEVRCVRCLALLQSVEKDYILREDLSVHRIGGIWRGTCVRCMVGLY
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RNJ1_STAAM
Sequence: MKQLHPNEVGVYALGGLGEIGKNTYAVEYKDEIVIIDAGIKFPDDNLLGIDYVIPDYTYLVQNQDKIVGLFITHGHEDHIGGVPFLLKQLNIPIYGGPLALGLIRNKLEEHHLLRTAKLNEINEDSVIKSKHFTISFYLTTHSIPETYGVIVDTPEGKVVHTGDFKFDFTPVGKPANIAKMAQLGEEGVLCLLSDSTNSLVPDFTLSEREVGQNVDKIFRNCKGRIIFATFASNIYRVQQAVEAAIKNNRKIVTFGRSMENNIKIGMELGYIKAPPETFIEPNKINTVPKHELLILCTGSQGEPMAALSRIANGTHKQIKIIPEDTVVFSSSPIPGNTKSINRTINSLYKAGADVIHSKISNIHTSGHGSQGDQQLMLRLIKPKYFLPIHGEYRMLKAHGETGVECGVEEDNVFIFDIGDVLALTHDSARKAGRIPSGNVLVDGSGIGDIGNVVIRDRKLLSEEGLVIVVVSIDFNTNKLLSGPDIISRGFVYMRESGQLIYDAQRKIKTDVISKLNQNKDIQWHQIKSSIIETLQPYLFEKTARKPMILPVIMKVNEQKESNNK
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J 1, RNase J1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPE50_MYCTU
Sequence: MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGPASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTGIRGAIVVETASASNTAGTPP
What are the official names of this protein?
Uncharacterized PPE family protein PPE50.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: EUTC_SHIDS
Sequence: MDQKQIEEIVRSVMASMGQTAPAPSEAKCTTTTCAAPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWGKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: PCNA1_SULAC
Sequence: MRIVYDDVRDLKNIVETLTKFIDEGLFEIGQDGIRLVAVDKAHVSLINIELYKELFKEYEVEDEFKFGFNSQYLAKILSIAKRKEEISIESDSPERVKITLGGALNRVFIINNIQVSPPEVPEVNLEFEVKASLSSKAFKTTINEISAVTDTVDIIAVEDKVILKGEGKEGSQIENEFSKDTGAISDMEFKNEAKSPYDVNYLSDILSLTNLSDYTRLAFSTEKPLELEFNMEGGGKVTYLLAPKLS
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen homolog 1, PCNA 1.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: RAS1_MUCCL
Sequence: MSKASSFVREYKLVMVGGGGVGKSALTIQFIQSHFVDEYDPTIEDSYRKQCVIDSETALLDVLDTAGQEEYSAMREQYMRNGEGFLLVYSITSRLSFEEITTFYQQICRVKDRDYFPMVLVGNKCDLEGDRQVSSQEGRDLAKNFGCQFIETSAKQRINVDEAFFEVVRDIRRYNKEQETRGHDQFGIQDAPDVASDKCCILM
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: FOG1_MOUSE
Sequence: MSRRKQSNPRQIKRSLRDMEAGEEAKAMDSSPKEQEAPDPEAPAIEEPPSPPREDVSPPAVPAPPESPEDPEDMEGQELEMRPQDEEKEEKEEEAAMASPWSGPEELELALQDGQRCVRARLSLTEGLSWGPFYGSIQTRALSPEREEPGPAVTLMVDESCWLRMLPQVLTEEAANSEIYRKDDALWCRVTKVVPSGGLLYVRLVTEPHGAPRHPVQEPVEPGGLAPVHTDIQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQRAGSPVSATEEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHNCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGFQQHSLMHSPLVPADKAPTPSSGLDSKAEVTNGETRVPPQNGGSSESPAAPRTIKVEAAEEPEATRASGPGEPGPQAPSRTPSPHSPNPVRVKTELSSPTPGSSPGPGELTMAGTLFLPQYVFSPDAGTTTVPTAPQASEILAKMSELVHNRLQQGAGSSGAAGTPTGLFSGTKGATCFECEITFNNINNFYVHKRLYCSGRRAPEDPPTVRRPKAATGPARAPAGAAAEPDPSRSSPGPGPREEEASGTTTPEAEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPPAPTTAPGPAAPALTAPPVRTRRRRKLYELPAAGAPPPAAGPAPVPVVPSPTAELPSSPRPGSASAGPAPALSPSPVPDGPIDLSKRPRRQSPDAPTALPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPLRTTALCPYCPPNGRVRGDLVEHLRQAHGLQVAKPAASPGAEPRTPAERAPRDSPDGRAPRSPSPAPENTPSDPADQGARTPSKGPPAPAPAPGGGGGHRYCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK
What is the function of this protein?
Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation.  Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3.  Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context.  The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1.  May be involved in regulation of some genes in gonads.  May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
What are the official names of this protein?
Zinc finger protein ZFPM1, Friend of GATA protein 1, FOG-1, Friend of GATA 1, Zinc finger protein multitype 1.
What is the protein family that this protein belongs to?
Belongs to the FOG (Friend of GATA) family.
Protein: KPR5_YEAST
Sequence: MSMSNIVVFGGDSHPELVTKICENLDIHPSKVELGKFSNGETNIALRESVREKDVYIIQSGCGQVNDTFMQLLILISACKSASASRVTAVMPYLCYSRQPDIPYTAKGAPIISKPKENYTFESHPGTPVSSSLMTQRPGAESSLKSLDSAIRSTINLENPQPIRTPNSSATANNNFDIKKTLSFSRIPMIPGGKLQNTSNSTDAGELFNAQNAGYKLWVVQAGTLIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYCKPIAQNYIQHRIPDYQDAVIVSPDAGGAKRATAIADALELSFALIHKERRSQLLKGPPDATLTSGGSLPVSPRPLVTTLVSSQNTTSSGATGVAALEMKKTTSTSSTSSQSSNSSKFVQTTMLVGDVRNKVCIIVDDLVDTSYTITRAAKLLKDQGSTKVYALITHGVFSGDALERIGQSSIDKLIISNTVPQDRTLQYLGKDRVDVIDVSCIIGEAIRRIHNGESISMLFEHGW
What is the function of this protein?
5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis.  Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 5, Phosphoribosyl pyrophosphate synthase 5.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TS15A_SOLHA
Sequence: MLVLSPSKSTQKLEFINTIQLLGVSYHFEHEIEESLSEIYNGYEEWIGESHNLHAVALSFRLLRQQGYYVSSDVFRKFTDDQGNYNKELVNDTHGLLSLYEAAHFRVHDEEILDEAINFTTTHFKLLLPKLSNSLSMQVSYALKYPINKTIARAATRKYISFYQEEKSSCDQVLINFAKLDFNILQKMYKREMCDITRWWKELDLANELGFARDRVVELYFWSLGVYFEPQYKVARNILTKVLCFVSITDDIYDTYGTLHELTLLTNAIERRNIDAIENLTSYMKLFFTALLHFYDEVEKELEKENKSFRVNFAISEMKKLVRAYFQEAKWYHGNTVPKMEEEYMKNGIQSSANPTLATASWLGMGDEATKEAFEWISTEPPILVASSNIARLLNDIVSHEREIERGDVASSIECYMNEYGATKEEAYMEIRKIIENNWKDLNRGCLKPTTVPRVLLMPVLNLTRVAEFVYKDEDAYTFSKNNLKDVIFMVLDDPIEE
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (PubMed:21818683).  No activity detected with geranyl diphosphate (GPP) and farnesyl diphosphate (FPP) as substrates (PubMed:21818683).
What are the official names of this protein?
Sesquiterpene synthase 15a, ShTPS15a.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.