PharMolix/UniProtQA huggingface dataset:
Protein: PURL_SULIM
Sequence: MGLNLLPIEMDDIRKRLDREPNEIEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGIKDWQDAGAVDIGDGWAIVIKVESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDMIRVGNLKIRKNVWLLKNIIAGIAAYGNSIGVPVVGGELSFDDTYNDNPLVDVAAIGIVRKDKIKPSIVDKAGLKLVLAGLTGIDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDVTLEIADKVEAIKDLGGGGLAVAVTEMANGLGAIVDIEKIPLRVKNMNPADVIISETQERMLYAVEEKNVEEVCKAFEEYEYPCSVIGEITSEPIIKFRYFGKDLVSLPTNALLEPPKFLWPIKNVRKNVEEKNVDLPLESTIYTVLSHPDLVSKEWVYSQFDYEVNTSTVVKPGDANGAVVSLPNGKLLAIKADGNPDLCSEDAYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKPEVYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENSQGKPIKPTPLIVMAGLVQGKLLKNRVEDSSYVVLLGYTRKELGGSLLSKIFKVPSQAPKVRLQEDLLSSEVVIDAINEEKITFAKDISRGGLAASLFNIIVHGYGVEISTKSILSDTDNVVENLFSESSGRFVILTNEPEWIVEKSRSKGIVASIIGKVNKKTSILTIDNTDYDLKTIVNNYFNFLEEVIGNG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_PRORU
Sequence: MTNIRKTHPLLKIVNHSLIDLPAPSNISAWWNFGSLLGLCLIIQILTGLFLAMHYTSDTTTAFSSVTHICRDVNHGWLIRYLHANGASMFFICLYMHVGRGIYYGSYTYLETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMVHLLFLHETGSNNPSGIPSNSDKIPFHPYYTIKDALGFLMLITLLLLLALFAPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILVLAIIPLLHTSKQRSMMFRPLSQTLFWILVADLMTLTWIGAQPVEHPFTTIGQVASVLYFALILILMPLAGLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OTC_MYCBP
Sequence: MIRHFLRDDDLSPAEQAEVLELAAELKKDPVSRRPLQGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQDTAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADLQTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLPDPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGLDRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVWDEAENRLHAQKALLVWLLERS
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRT14_KLULA
Sequence: MSSLAAAHATNAVNALLQSVLPGSASVNAERKKTSRDKGSKAQLIDRNLKKRVEVQEKDVYRIKKREKKMLRKKISGRKEVQEDIEQKAKLQVLRKHQVDNSLTDHEKSYLDKVVKKNVRNLKSWDYDDKEELLDLQKQILANSEDSKKVRKVKSRRQKKKQFKEKLPQSIQDHRYKALTPGLAPVGASDEEESEDEDEDY
What is the function of this protein?
Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription 14.
What is the protein family that this protein belongs to?
Belongs to the RRT14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL26_SCHPO
Sequence: MKFSRDVTSSRRKQRKAHFGAPSSVRRVLMSAPLSKELREQYKIRSLPVRRDDQITVIRGSNKGREGKITSVYRKKFLLLIERVTREKANGASAPVGIDASKVVITKLHLDKDRKDLIVRKGGKVE
What are the official names of this protein?
60S ribosomal protein L26.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: UBIX_SALTI
Sequence: MKRLIVGISGASGAIYGVRLLQILRDVDSVETHLVMSQAARQTLALETHFSLREVQALADVTHDARDIAASISSGSYPTAGMVILPCSIKTLSGIVHSYTDGLLTRAADVILKERRPLVLCVRETPLHIGHLRLMTQAAEIGAVIMPPVPAFYHLPQTLDDVINQTVNRVLDQFDIPLPHDLFVRWQGA
What is the function of this protein?
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.  The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
What are the official names of this protein?
Flavin prenyltransferase UbiX.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family.
Protein: NBN_MOUSE
Sequence: MWKLLPAAGAAPGEPYRLLAGVEYVVGRKNCGILIENDQSISRNHAVLTVNFPVTSLSQTDEIPTLTIKDNSKYGTFVNEEKMQTGLSCTLKTGDRVTFGVFESKFRVEYEPLVVCSSCLDVSGKTVLNQAILQLGGLTANNWTEECTHLVMSAVKVTIKTICALICGRPIIKPEYFSEFLKAVESKKQPPDIESFYPPIDEPAIGSKSVDLSGRHERKQIFKGKTFVFLNAKQHKKLSSAVAFGGGEARLMAEDDEEEQSFFSAPGTCVVDVGITNTQLIISHSQKKWIHLIMDTLQRNGLRPIPEAEIGLAVIFMTTENYCNPQGQPCTELKTTTPGPSLSQVLSANGKIIPSAPVNMTTYVADTESEPADTCMPLSERPEEVKIPGLEQSSRKLSQETFNIKEAPKPSSKANNVASDTLVRGKTPSYQLSPMKFPVANKNKDWTSQQQQNSIKNYFQPCTRKRERDEDNPELSSCKSSRMELSCSLLEQTQPAGPSLWKSKEHQSQNATLDREADTSSVGGMDIELNRKSPDRKPLPTETLRPRKRKDVDLATEEEVLEELLRSTKPELAVQVKVEKQEADDTIRKKPRMDAERNRPLNGGSEPESNSALQEDEREKKDELQTESWSTKHEIANSDGLQDSSEELPRKLLLTEFRSLVVSNHNSTSRNLCVNECGPLKNFKKFKKATFPGAGKLPHIIGGSDLVGHHARKNTELEEWLKQEMEVQKQQAKEESLADDLFRYNPNVKRR
What is the function of this protein?
Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity.  The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.  The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11.  RAD50 may be required to bind DNA ends and hold them in close proximity.  NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions.  It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX.  NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation.  NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints.  The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability.  Forms a complex with RBBP8 to link DNA double-strand break sensing to resection.  Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex (By similarity).
What are the official names of this protein?
Nibrin, Cell cycle regulatory protein p95, Nijmegen breakage syndrome protein 1 homolog.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Chromosome, telomere. Chromosome. Note=Localizes to discrete nuclear foci after treatment with genotoxic agents. Acetylation of 'Lys-5' of histone H2AX (H2AXK5ac) promotes NBN/NBS1 assembly at the sites of DNA damage.
Protein: RS3_CAMC1
Sequence: MGQKVNPIGLRLGINRNWESRWFPTKQSLPENIGEDYKIRAFLKKKLYYAGISQILIERTAKKLRVTVVAARPGIIIGKKGQDVENLKNEVSKLIGKEVNVNIKEERKAQASAQLAAENVAMQLEKRVAFRRAMKKVIQGAQKSGAKGIKISVAGRLGGAEMARTEWYLEGRVPLHTLRAKIDYGVAEAHTTYGNIGIKVWIFKGEVLQKGVQPEKTEEEAPKKTRRARRGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PTH_CHLAD
Sequence: MWLIVGLGNPGERYARTRHNIGFRSVETLAERHGLTFRNQRAKSEIAEGIIRGQRVALVKPQTYMNLSGQAVAALRQWYKIDPARELLVIYDDLDLPFAKLRLRERGSAGTHNGMRSIVGQLGTTEFPRLRIGIGQPPGQMDAADYVLSRFTPEEEAVLPEVLARVADAVEVVVSEGLTAAMNRYNPL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCRI1_MOUSE
Sequence: MTSSPVSRVVYNGKRNSSPRSPTNSSEIFTPAHEENVRFIYEAWQGVERDLRSQLSSGERCLVEEYVEKVPNPSLKTFKPIDLSDLKRRNTQDAKKS
What is the function of this protein?
The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition.  Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s).  When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition.
What are the official names of this protein?
Mapk-regulated corepressor-interacting protein 1, Protein FAM195B.
What is the protein family that this protein belongs to?
Belongs to the MCRIP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, Stress granule.
Protein: RL5_GEOTN
Sequence: MNRLKEKYTKEVVPALMSKFNYKSIMQVPKIEKIVINMGVGDAVQNPKALDSAVEELTLIAGQRPVVTRAKKSIAGFRLRQGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFRGVSKKAFDGRGNYTLGIKEQLIFPEIDYDKVNKVRGMDIVIVTTANTDEEARELLTLLGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PNP_DESHY
Sequence: MTQEVLERSIQVGGRTMTFQTGKIGKQAGGAIFCRYGDTVVSAFATGSAQPREGIDFFPLTVEFEERLYAAGKIPGGFIKREGRPSEKAILSARLIDRPIRPLFPEGYRNDVQVVAQVMSVDQDCASDITGINAASAALTISNVPFEGPVAAVTVGLIGDEFIINPTVEQSEKSVMHLTVAGTKDAVMMVEAGAQEVPEAQMLEAIMFGHREIQRIAEFIENYRLEALERNLAKPKQEVVMKQMPEEIVQAVKAFAYDKMDQAVRTEEKKAREEAIRQVKEEALAHFAEQYPEDSKTIDKILEDFVHKIVRRLITVEHIRPDGRALDEIRPISVEVGILPRTHGTGLFTRGQTQVLTVATLGAVGDEQILDGLGLEESKRYMHHYNFPPYSVGETRPMRGPGRREIGHGALAERALLPVIPDENDFPYTIRLVSEVLESNGSSSMASVCGSTLSLMDAGVPVKSPVAGIAMGLISEENHIAILSDIQGMEDHDGDMDFKVAGTSQGVTALQMDIKIKGVSREILERALTQAKEGRLFILDKMLSVIEKPRPELSPFAPRIITASIHPDKIREVIGPGGKTIKKIIDETGVKIDIEDDGRVFISAVDGEAGENALKIIQALTQEVEVGRIYNGRVTRIMDFGAFVEVIPGVLGLSGKEGLVHISQLAHGRVEKVEDVVKLGDDILVKATGIDKQGRLNLSRKEALPNPNPSSNPNPNGITANRNPRNS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_YERP3
Sequence: MEQFEAISVEQAYLRWKEGKTALVDIRDPQSYEAGHAPGAFHLTNSSLHTFMQQTDFDQPVMVMCYHGNSSKGAAQYLLQQGFDVVYSIDGGFEAWARSYPQDITSESR
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_SALDC
Sequence: MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIRVDEPYILVVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKCGVPWLYRFELMGTQRDIDNVRKGVNEFWQQLSRSA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: COR2B_HUMAN
Sequence: MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNSPKNC
What is the function of this protein?
May play a role in the reorganization of neuronal actin structure.
What are the official names of this protein?
Coronin-2B, Coronin-like protein C, Clipin-C, Protein FC96.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL16_BUCBP
Sequence: MLQPKNTKFRKMHKGKNRGLAIGTNVHFGLYGLKAITRGRLKSSQIESARRAITRAIKRQGKIWIRIFPDKPITKKPLEVRMGKGKGNVEYWVALVQPGKILYEISGVSEELSRIAFKLAAAKLPVKTMFVTKLVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RRF_YERPY
Sequence: MINEIRKDAEVRMEKCLEAFQNHISKIRTGRASPSILDGIQVEYYGTATPLRQLANIVVEDSRTLALTVFDRSLSAAVEKAIMTSDLGLNPSSAGTVIRVPLPALTEERRKDLIKVVRAEAEQGRVSIRNVRRDANDKVKALLKDKEISEDEDRRSQDDVQKLTDAYIKKVDAALAVKEAELMDF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRLO_DICDI
Sequence: MKKVFFLILILNCVVGALSNKNICKISLLLSGDYNDIGVNYMFNYARTQVEKNLNINSIVFTNLENNQNAINNAIIESINKGSNFLISTINSHSNFIINYSRLYKNKEIFWLIKGNDNERPIPDDLPRVKILNINSDLSFYYLGFISSLISKTGKIGFISTKNIETDYQRLTNAFYIGAINSNPNITFLVCSNNFNNQNNNKKISYKISKLLISKGVDFIGSDQDDNSIQLAVIDNGGIGLGLTGFEYSKIYNDKFPFSFKLEWSQLLIDITNTIINGSWVDYDIIYITSFSRLNGTTNFTPEIEPIINYNFIPKIYQKQINDEINKLKNHSTNYYFPHLCNNLFNNIYNQKQTNGCITNEQFSNSHLLNASNIKIIDNKEILEFVDSYSNSIKISILSVSIFCIFICVLGMIFITVLRNARILKSSSPSFLLLILFGCIVIFTGCILFSQPATDKTCQGRVWLLSIGYTIFLGSLLIKNWRVWLLFDNKKLRKRSITNWKLYPWVAGILVVDVLILALWQGLGDIKSESRIIGTSFYQYTNVCTNNDQGSIALYILLAFHGLKLLGTCFISFKIKLVDIEEFNESKPITTSVFIILFCIFTIILLIAPSSSSSSASSPQPIASLETIICICSVTTTAISIGLLFGDKIYFITTQGLGLNQTFAKSSSFSLDKKDCDDDDDDSSDGSDHSNSNKNKNKNKNRNQSEKKKRPNSIKPIGLFSKSKQESVVFNPPSNNDLTNELALPIEGIKEGHGHDSENNDEYEHHEDEDHEYEGEGEDEDHEDEYEVENDIEQEQEQESSNISISTKKNNENEIISDT
What are the official names of this protein?
Metabotropic glutamate receptor-like protein O.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SAC1_MOUSE
Sequence: MAAAAYEHLKLHITPEKFYVEACDDGADDVLIIDRVSTEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLVVITKKMKVGECFNHAVWRATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLSMDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSGNRASFVQTRGSIPIFWSQRPNLKYKPHPQISKVANHMDGFQRHFDSQVIIYGKQVIINLVNHKGSEKPLEQTFANMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGKVVTNQDGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKTYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLLMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID
What is the function of this protein?
Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 3-phosphate (PtdIns(3)P) and has low activity towards phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).  Shows a very robust PtdIns(4)P phosphatase activity when it binds PtdIns(4)P in a 'cis' configuration in the cellular environment, with much less activity seen when it binds PtdIns(4)P in 'trans' configuration (By similarity).  PtdIns(4)P phosphatase activity (when it binds PtdIns(4)P in 'trans' configuration) is enhanced in the presence of PLEKHA3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol-3-phosphatase SAC1, Phosphatidylinositol-4-phosphate phosphatase, Suppressor of actin mutations 1-like protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Trafficking between the ER and Golgi is regulated by nutrient status and by TMEM39A. Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS) in the presence of phosphatidylinositol-4,5-bisphosphate.
Protein: GCS2_KLEP7
Sequence: MPLADFHRSDPFTLGIELELQVVNPPGYDLSQDASTLIADVQHELTVGEAKHDITESMLEIATGVCRDISHAQIQLSAIQQAVQRAALRHHLQICGGGSHPFHAWQRQQISDNPRYVKTVEHFGYLAQQATVFGQHVHVGCQSGDDAIYLLHGLSRFVPHFIALNAASPWFDSTDSRFACSRLNRFSSYPDNGPMPWVADWQGFRRLFRQLSYTSMIDSMKDLHWDIRPSPQFGTVEVRVMDTPLTLAQAIHIAGFIQTLACWLLTERPFKHQPDDYLLYPFNRYQACRYGLDGTLTDVRSGEQRSIRQEILQLADRLAPFAHQLKATAALEAVVRQAKSPHSEAQQMRDFIANGGSLSGLVQKHCEIWAA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: CYML4_MELLF
Sequence: GKPICGETCFKGKCYTPGCTCSYPICKKN
What is the function of this protein?
Probably participates in a plant defense mechanism (Potential).  Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (PubMed:26322745).  In vitro, displays cytotoxicity against cultured cells (PubMed:26322745).  Not active against Gram-negative bacterium E. coli ATCC 25922 or Gram-positive bacterium S. aureus ATCC 25923 up to a concentration of 64 uM (PubMed:26322745).
What are the official names of this protein?
Cyclotide mela-4.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebuis subfamily.
Protein: RSE1_KLULA
Sequence: MTQDSEVLLWHTVLQRHRNYVHSCIGDFTLDRSSLATAEADTTSVKGPRSSKKRKELQLCLATQDCVELYDVSNGTLDALGKWPIAATILSMTKLNMDRCSHTILVLITDSGNLTFWQFERDSVSGKVYVRTLANEPISRSGIRRFVPQYQMVSDPQSRCVFFSGIERSKMCVLADWQRGKLVVGSPIEIQRSDRITLASAACDVSFDNPVNAAIEVESGTNDYYLSFYTMDLGLNTLLLRKEHLLEDKSINFVMQCPNLQQYKIKTRPNDETDQDSVNPFVICGYDGYLTLIDLEGFYEVSVQLPVRKTVSSTNIINGTIHKLKKDFFILMQSNHGDMYKVGIIPDEETKAPVLEIAYFDTLPTSEDIHIFKSGALFNVSEFGTSYLTQFESLGEDLEKITSYTPGRRSFIETESTLKNLSILDSLTSLNPLTSFHASNSTPLTILAAANQTENLVKLTSAVDFEELISTTLPRIPSKLWTVRIPKNETHSLIFLSMETSTTILKIHEGTVEDFGGDSNPFILNKPSLFVGAMVQRSIIQVTRDCLLQIIEMHDGPYTKKLEWYPPAGVGIVTAFCNETQLVVALTNHEICYFEIIEDSLNELQDRVEMDSTVNSIALLAGQKSGYCVLGCEDSSLQILNLQSKHPDFFTICAIQSLISKPHSLLFMRDTSDLKIHVGMKSGVYLSSKLNINDGTVFDVRTRFVGTKPVQVNLLDNIDINHKDDDDDEPGENDSKIDDFKKKISDFTPLVVLNSSISWVTYEIDDKITLRPLKTDEGITLKHINAFITDDIKRNGCCSITSKGQLLIGKLDNFLSWSNWFNEKKYTLVNDELKNAGNEEEDEDEDEDEDEDASEKYEIVGYQSQRILSDTTDNSLSYVISKTANKETSLSAIRDDKLLATNNGNTVVIIAKEVFNAVCSCNFGTNVKYIVISTESGKFIVIQIRVKNNVLETQYIHETMVHSKVNAMVSFGDKLACCILGNVVLFGLGKKQLLRKSITEMPPYITQVTALDQWDGTMLAVGDIRESVTIFKYDIDNNSFIGVADDIVKRHVTTVKFIDVSSVIGGDRFGNCWVLRVNYESDTRVASNIKACQYTLETLCHMYMNDTPMKFEIVNHMNMSDRPAILWIGLQGTIGCFVPLITRKEQQLYQSFQSTYAELDVLHFQDNNKPEEVDLEETEGALDEAYHTTKNTDHQDYVEGVISRVGRDFLSYRSSYAPSKNIIDGETLEQLTTYLPSDQRWIASKMKHADSGKLDIFNKYINEMRTNYV
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.
What are the official names of this protein?
Pre-mRNA-splicing factor RSE1.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IDLC_CHLRE
Sequence: MIPPLSSLVRYDNPVLVSTSKDKGKGAKGTPGKKGALPPVEQKPGLTQTEDILNSILPPREWTEDGQLWVQYVSSTPATRLDVINLQEKLDQQLQQRQARETGICPIREELYAQTFDELIRQVTINCAERGLLLLRVRDEMRMTIAAYQTLYESAVAFGIRKALQTEQGKSEMESRITQLEGDVKDLERQVQEWKFKCEAIEKRESERREVEAKKHKDEVAYLENYAKQLKQQLETFLVPAKKGAPGAPAAAT
What is the function of this protein?
Plays a dynamic role in flagellar motility.  May be necessary for stable assembly of a subset of inner dynein arms or for the binding of these arms to the outer doublet microtubules of the axoneme.
What are the official names of this protein?
28 kDa inner dynein arm light chain, axonemal, p28.
What is the protein family that this protein belongs to?
Belongs to the inner dynein arm light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme. Note=Present along the entire length of the axoneme.
Protein: RECA_FRAT1
Sequence: MSKEKALESALSQIEKQFGKGAIMRLGDQEAAHDIDVIPSGIIALDVALGIGGYPKGRIIEIYGHESSGKTTLTLLAIAQCQKQGGTAAFVDAEHALDPKYAKLLGVDVDNLIVSQPDTGEQALEIADMLVRSGGVDIVVIDSVAALTPKAEIEGDMGDSHMGLQARLMSQALRKLTANIKRSNTLVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLEVKKGGSIKDGIDVSGNEIKVKVVKNKVAPPFKQADFELIYGEGISLEAELIDLGAKYNIIEKSGAWYSYKGKKIGQGKEKSKEYLKENTAERDEIERAILELLLPNKYSNKDSNDSPKEGSKIKTKVNPAVTQDELI
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK5_PERRU
Sequence: SGETSGEGNGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, FXPRL-amide, PerRu-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDPA_GLAP5
Sequence: MSINVTEIVLHQLQQTAGETAELHTVLREDLLAISPEVEQMMLQLHQAYQNKAKAYGIFQSESIFAQQLNRLLEGESEFLPFSHSCAKMLATELVKYPFASGGTFILCRYTFLATEYLFIALIDSRASMLVDDKLEVKRTEYLDITQYDIACRINLTELKHNAQSNRYLTFIKGRVGRKVADFFMDFLGAEEGLNPQVQNQTLLQAVSDYCEQGELDSNQTQAVKKQVFEYCKGQINSGEEIAISELSASMPTLKEIDFADFAEQQEYGLEESIPPVRNALKTLTKYSGSGKGVTISFDAELLSQRIIWDELNDTLTIKGLPANLRDQLERNK
What are the official names of this protein?
Nucleoid-associated protein HAPS_0704.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.