PharMolix/UniProtQA huggingface dataset:
Protein: MAZF_ECOLI
Sequence: MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
What is the function of this protein?
The physiological role of this TA system is debated.  Programmed cell death (PCD) occurs when cells are at high density and depends on the presence of MazE-MazF and a quorum sensing pentapeptide, the extracellular death factor (EDF) with sequence Asn-Asn-Trp-Asn-Asn (NNWNN), probably produced from the zwf gene product glucose-6-phosphate 1-dehydrogenase (PubMed:17962566, PubMed:18310334).  Cell death governed by the MazE-MazF and DinJ-YafQ TA systems seems to play a role in biofilm formation, while MazE-MazF is also implicated in cell death in liquid media (PubMed:19707553).  Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment (PubMed:20005847, PubMed:23416055).  In conjunction with EDF prevents apoptotic-like death (ALD) in the presence of DNA damaging agents, probably by reducing recA mRNA levels in a non-endonuclease-mediated manner (PubMed:22412352).  Other studies (in strains BW25113 and MC4100, the latter makes EDF) demonstrate MazF does not cause PCD but instead bacteriostasis and possibly a dormant state as well as persister cell generation (PubMed:24375411).
What are the official names of this protein?
Endoribonuclease toxin MazF, Toxin MazF, mRNA interferase MazF.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: UBS3A_HUMAN
Sequence: MAAGETQLYAKVSNKLKSRSSPSLLEPLLAMGFPVHTALKALAATGRKTAEEALAWLHDHCNDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESKRQCAKNRAHEVFPHVTLCDFFTCEDQKVECLYEALKRAGDRLLGSFPTAVPLALHSSISYLGFFVSGSPADVIREFAMTFATEASLLAGTSVSRFWIFSQVPGHGPNLRLSNLTRASFVSHYILQKYCSVKPCTKQLHLTLAHKFYPHHQRTLEQLARAIPLGHSCQWTAALYSRDMRFVHYQTLRALFQYKPQNVDELTLSPGDYIFVDPTQQDEASEGWVIGISQRTGCRGFLPENYTDRASESDTWVKHRMYTFSLATDLNSRKDGEASSRCSGEFLPQTARSLSSLQALQATVARKSVLVVRHGERVDQIFGKAWLQQCSTPDGKYYRPDLNFPCSLPRRSRGIKDFENDPPLSSCGIFQSRIAGDALLDSGIRISSVFASPALRCVQTAKLILEELKLEKKIKIRVEPGIFEWTKWEAGKTTPTLMSLEELKEANFNIDTDYRPAFPLSALMPAESYQEYMDRCTASMVQIVNTCPQDTGVILIVSHGSTLDSCTRPLLGLPPRECGDFAQLVRKIPSLGMCFCEENKEEGKWELVNPPVKTLTHGANAAFNWRNWISGN
What is the function of this protein?
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases.  Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.  Exhibits negligigle protein tyrosine phosphatase activity at neutral pH.  May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation.  May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
What are the official names of this protein?
Ubiquitin-associated and SH3 domain-containing protein A, Cbl-interacting protein 4, CLIP4, Suppressor of T-cell receptor signaling 2, STS-2, T-cell ubiquitin ligand 1, TULA-1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GREA_SYNAS
Sequence: MEKMPITKSGFENLKKELEHLKCVLIPANIKDIEIARAHGDLSENAEYTAAKEKQSFLHGKLQELENNLALSNVIDLKMLSDDRIVFGATVIIEEASTGKQTNYQLVGPFESNISENKISVTSPIGKALIGKSIGDEVKVHTPGGIRNFEVVDIYINPSEL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: PLSY_ALKMQ
Sequence: MINLLVIISAYFIGNFSTSFIVGKLTSNIDIRQHGSGNAGSTNVLRTLGVKAAALTFLGDTLKGMLSFYLAQRFVGEQAALMAGIAVVIGHNWPVLLGFKGGKGIATTIGVALIASPLAAIASISLGVVILYRYKYVSLSSITAMTILPFFLFSYGLEYFIFGLVLSVMAIYRHRENIKRLRTGTEKKIGRKTSV
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCST_DICDI
Sequence: MISQNIIKIIQKSNKRYFSSSNELKKTALNELHKELGAKMVPFCGWEMPVQYPAGVMKEHLHVRKESGLFDVSHMGQLRIHGKDRVKFFESIVVADLQALPTGHSKLSVFTNEKGGIIDDTMITNAGDSLYVVVNAGCADKDISHINEKIKEFKSVNPTHDVSMQLLEDLSLIAIQGPTTESILQKFVKDQDITNMEFMTQRPMTIAGIDCIVTRCGYTGEDGFEISVPSKQAVRLAELFLATSNASIESGIKPAGLGARDSLRLEAGLCLYGHDLNDDITPIEASLNWLISKRRREEGGFPGASIIQKQLQKDGCPQKRVGVIINGAPAREGCLILDPSTNQEIGKVTSGTISPITRQSISMAYVKTPFSKIGTQVNVSIRGKPITATISKMPFVPTNYKKL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, mitochondrial, Glycine cleavage system T protein, GCVT.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NDK_PYRAE
Sequence: MPVEKTLLILKPDAVARGLVGEIISRFEKAGLKIVALKMVKASPEEIERFYPSSEEWLRSAGQKLLKAYQELGIDPRAKIGTDDPVEVGRIIKRSLVKYMTSGPIVVMVLKGNRAVEIVRKLVGPTSPHSAPPGTIRGDYSIDSPDLAAEEGRVVFNLVHASDSPSEAEREIRFWFREEEVLE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CISY_BRADU
Sequence: MDAKASNKTATLTVGNKNYDLPIHSGSVGPDVIDIGKLYGQSGLFTYDPGFTSTASCQSKITYIDGDAGVLEYRGYPIEQLAENGDFLETCYLLLYGNLPTAAQKKDFDDRVIHHTMVHEQMARFFQGFRRDAHPMAVMVASVGALAAFYHDSTDINDPKQRMIASMRMIAKIPTLAAMAYKYTIGQPFVYPKNSLKFAENFLHMCFAVPCEEYKINPVLADALDKIFILHADHEQNASTSTVRIAGSSGANPFACIAAGIACLWGPAHGGANEAALAMLAEIGSVDKIPEFIAKVKDKNSEVRLMGFGHRVYKNYDPRAKIMQKMCHAVLKETGHGDDPMLKVAMELEKIALSDQYFIDRKLYPNVDFYSGITLKAMGFPVSMFTVLFAVARTVGWISQWSEMIEDPQQKIGRPRQLYTGVTRRDYVAIKDRK
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: HFA2C_ORYSJ
Sequence: MDPAAAGIVKEEMLESQQQQRQEDGGAAPRPMEGLHEVGPPPFLTKTYDLVEDPATDGVVSWSRAGNSFVVWDPHVFADLLLPRLFKHNNFSSFVRQLNTYGFRKVDPDRWEFANEGFLRGQRHLLKTIKRRKPPSNAPPSQQQSLTSCLEVGEFGFEEEIDRLKRDKNILITEVVKLRQEQQATKDHVKAMEDRLRAAEQKQVQMMGFLARAMRNPEFFQQLAQQKEKRKELEDAISKKRRRPIDNVPFYDPGETSQTEQLDSPYLFDSGVLNELSEPGIPELENLAVNIQDLGKGKVDEERQNQTNGQAELGDDFWAELLVEDFTGKEEQSELDGKIDGIDELAQQLGYLSSTSPK
What is the function of this protein?
Transcriptional activator that specifically binds DNA of heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor A-2c, Heat stress transcription factor 25, OsHsf-25, Heat stress transcription factor 6, OsHSF6, rHsf6.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSMH_METS4
Sequence: MSGAPHIPVLLAEVRGVLRLGEGPGVVVDGTFGAGGYSRALLAADPDLRVIAIDRDPTAVAAGQELAAAAGGRLRLVQGRFGDLDAIVRREGVEAVDGVVLDIGVSSMQLDRAERGFSFRADGPLDMRMEGAGTSAADLVNGAPEAELADIIYHFGEERRSRAVARAILEARRRAPIATTGALAEIVAGVVRAEPGSGIHPATRTFQALRIAVNDELGELNRALHAAERILRPGGRLAVVTFHSLEDRIVKQFFSARSGRAVSASRHLPMAERPVPRSFTLVTKGPVGPSEAEAAANPRARSAKLRAGERTDAPAPEPLAALAALAALPPRERGGRR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_GRABC
Sequence: MPQYRSRTTTHGRNMAGARGLWRATGMKDGDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGKTVVKGATRALDLVDAMVVAADESYTDEEVQAVERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSVLATHADREKLFREAGHLIVDLARRWYEQDDVSATPRGIATHAAFENAMSLDIAMGGSTNTVLHLLAAAQEAGVDFTMADIDRLSRRVPCLCKVAPAKSDVHMEDVHRAGGIMAILGELERAGLLDASRPTVHAPTLKDALERWDIGRTSSEEVRTFFRAAPGGVPTQVAFSQSARWDSVDEDRQKGVIRSTEHPFSHDGGLAVLFGNLAPEGCIVKTAGVDESILTFRGTARVYESQDAAVSGILGGQVVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKLCALVTDGRFSGGTSGLSIGHVSPEAAEGGLIALVETGDPVLIDIPNRIISIALPDEVLAARRTAMEAKGEAAWKPAERQRKVSPALRAYAAMTTNAARGAVRDVSQVERKR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TF2H1_DROME
Sequence: MTTSSEDVLLQMGEVRYKKGDGTLYVMNERVAWMAEHRDTVTVSHRYADIKTQKISPEGKPKVQLQVVLHDGNTSTFHFVNRQGQAAMLADRDKVKELLQQLLPNFKRKVDKDLEDKNRILVENPNLLQLYKDLVITKVLTSDEFWATHAKDHALKKMGRSQEIGVSGAFLADIKPQTDGCNGLKYNLTSDVIHCIFKTYPAVKRKHFENVPAKMSEAEFWTKFFQSHYFHRDRLTAGTKDIFTECGKIDDQALKAAVQQGAGDPLLDLKKFEDVPLEEGFGSVAGDRNVVNSGNIVHQNMIKRFNQHSIMVLKTCANVTSAPSTMTNGTNNANGPVSQSAYTNGMNGKGQATATATKSSSDQVDKDEPQSKKQRLMEKIHYVDLGDPILEGDDSANGEKAKSKHFELSKVERYLNGPVQNSMYDNHNDPMSLEEVQYKLVRNSESWLNRNVQRTFICSKAAVNALGELSPGGSMMRGFQEQSAGQLVPNDFQRELRHLYLSLSELLKHFWSCFPPTSEELETKLQRMHETLQRFKMAKLVPFENRAMHELSPLRSSLTQHLNQLLRTANSKFATWKERKLRNTR
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription factor IIH subunit 1, TFIIH basal transcription factor complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TFB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSAL_TRIV2
Sequence: MAQAVDASKNLPSDPRNREVVFPAGRDPQWGNLETPVNASPLVKWFINNLPAYRPGLTPFRRGLEVGMAHGYFLFGPFAKLGPLRDAANANLAGLLGAIGLVVLFTLSLSLYANSNPPKALASVTVPNPPDAFQSKEGWNNFASAFLIGGIGGAVVAYFLTSNFALIQGLVG
What are the official names of this protein?
Photosystem I reaction center subunit XI, PSI subunit V, PSI-L.
What is the protein family that this protein belongs to?
Belongs to the PsaL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.
Protein: F200A_MACFA
Sequence: MTPESRDTTDLSPRGTQEMEGIVVVKVEEEDEEDHFQKQRNKVESSPQVLSRSTTMNERALLSSYLVAYRVAKEKMAHTAAEKIILPACMDMVRTIFDDKSADKLRTIPLSDNTISRRICTIAKHLEAMLITRLQSGIDFAIQLDESTDIASCPTLLVYVRYVWQDDFVEDLLCCLNLNSHITGLDLFTELENCIVGQYKLNWKHCKGISSDGAANMTGKHSRLTEKLLEATHNNALWNHCFIHREALVSKEISPSLMDVLKKAVKIVNFIKGSSLNSRLLEILCSEIGVNHTHLLFHTEVRWLSQGKVLSRVYELRNEIYIFLIEKQSHLANIFENDIWVTKLAYLSDIFGILNELNLKIQGKNNDIFQYLEHILGFQKTLLFWQARLKSNRPSYYMFPTLLQHIEENIINEDCLKEIKLEILLHLTSLSQTFNYYFPEEKFESLKENIWMKDPFAFQNPASIIKLNLEPEEENELLQLSSSFTLKNYYKTLSLSAFWIKIKDEFPLLSRKSISLLLPFTTTYLCELGFSILTRLKTKKRNRLNSAPDMRVALSSCVPDWKELMNRQAHPSH
What are the official names of this protein?
Protein FAM200A.
What is the protein family that this protein belongs to?
Belongs to the FAM200 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YIDC_ECO27
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNC_BUCA5
Sequence: MNHIVTKKIQKVLGYTFTHKDLLKQALTHRSASSKHNERLEFLGDSILSFVIANALYQHFPYIDEGDMSRMRATLVRGNTLAEIAYEFDLGEYLKLGQGELKSGGFRRESILANTVEALIGSIYLDSNIKTVEELILKWYEKRLEKISPGDTQKDPKTRLQEYLQSKHLSLPLYFIVEVYGEAHNQLFTIHCKISTISEYLIGTGSSRRKAEQDAAQKALIKLGVE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_HALMA
Sequence: MLHVGINGFGTIGKRVADAVRVQPDMTVAGVAKRSPNFEATIADDRGYDLYAADGREPFDEADLGTAGTVHDLIETSDVVVDTTPSGVGAANASLYAEHDTPAIFQGGEDADVADVSFNARANYEKAVGADTARVVSCNTTGLSRLLAPLRESYGVEKSRVTLVRRGADPGQTGRGPINDTLPDPVEIPSHHGPDVQTIFPDLDIDTMGMKVPTTQMHTHSVNVTLESEPATEEVTALLADESRLFLIPETLGIDGAGKLKEYTRDAGRPRGDVWENCIWAESITVEGRDLYLFQAIHQEADVVPENIDAVRALSERTASAEKSIRRTDEALGVGRGLVEHDGSPQRVDSHADD
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2826_VIBCH
Sequence: MKPMQRLTCLLALCFAASASAKVTMEIPDTIDLLVVNGSSPKLSGGFFDATKKLELEDGEQQIVFRYSPYFSQGNDRIIIDSEVVIATFDAANQELRFDMPKYRDAPQATKAIKTMQWQLLDQQGKAVELRQDRLIKEGMQIGRNFEFETAEYNKKGGVAALTSSMAVQPIAQQEISNATAMAAAEEMLHFWYNKADAETKARFKAFVNQQ
What are the official names of this protein?
UPF0319 protein VC_A0026.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: HGH1_XENTR
Sequence: MDPALCLELLSFLKPETRADVRAQALEYILGVSGSPEGRQSLCAEPRLLCALLDLSTEQSPHVAQDAHHVLVNLTSDCAAHRALLAHVPTLLPSMLSRLRDPGCPFADSICTALCNLSREEETCQSFLRSLTQEGMCQLLDMLCAPKYNPRASLDYLGPLLCNLTQLPEGRHFILDRNRCVVQRLLPYLQSGSTVRRGGIVGTLRNCCFSHRDHAWLLGDDVDLLPFLLLPLAGGEEFTEEEMETLPPDLQYLAEDKQREADPDIRKMLIETVLLLCATADGRRLVKQRGTYLVMRELHSWEREPCVKRACEKLIQMLIGEEPEAGLENLLEVTVPPDLEETLSRLDKEEEGPQGTLVQ
What are the official names of this protein?
Protein HGH1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HGH1 family.
Protein: FYN_XENLA
Sequence: MGCVQCKDKEATKLTDERDNSLTQSLGYRYGTDPTPQHYPSFTVTTIPNYNNFHATAGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFQKGEKFQILNSSEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTYLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVARGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMLNCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGDNL
What is the function of this protein?
Tyrosine-protein kinase implicated in the control of cell growth.  Plays a role in the regulation of intracellular calcium levels (By similarity).  Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension.  Blocks axon outgrowth and attraction induced by ntn1 by phosphorylating its receptor ddc.
What are the official names of this protein?
Tyrosine-protein kinase Fyn, Proto-oncogene c-Fyn, p59-Fyn.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Protein: VLYS_BPAPS
Sequence: MSEFCKPLLDILRHQGTCAALAFIMALLRARYHRKDFYRSLLDALMCAMLGGVAHELLQFLGLKADYSWLASVAIGYLGVDRIGNWLKKKTGKL
What is the function of this protein?
Essential for lysis of the bacterial cell wall by disrupting the cell membrane, thereby giving hydrolytic enzymes access to the cell wall.
What are the official names of this protein?
Putative lysis protein S, p11.
What is the protein family that this protein belongs to?
Belongs to the lambda phage S protein family.
Protein: CKX9_ORYSJ
Sequence: MRPSLLQYLKLLLLLALGGVTTMHVPKQDVPSSLEELTLDGHFSFHDVSAAAQDFGNLSSFPPVAVLHPGSVADIATTIRHVFLMGEHSTLTVAARGHGHSLYGQSQAAEGIIISMESLQSNTMRVNPGVSPYVDASGGELWINVLHETLKYGLAPKSWTDYLHLTVGGTLSNAGVSGQTFRHGPQISNVNELEIVTGRGDVITCSPEQNSDLFHAALGGLGQFGVITRARIPLEPAPKMVRWLRVLYLDFTSFTEDQEMLISAEKTFDYIEGFVIINRTGILNNWRSSFNPQDPVRSSQFESDGKVLFCLEMTKNFNPDEADVMEQEVNTLLSQLRYMPSSLFHTDVTYIEFLDRVHSSEMKLRAKGMWEVPHPWLNIIIPRSMIHKFAKEVFGKILKDSNNGPILLYPVNKSRWDNRTSVVIPDEEVFYLVAFLSSALGPHNIKHTLDLNYRIIEFSDKAGIGVKQYLPNYTTEQEWQSHFGARWDTFQQRKKAYDPLAILAPGQRIFQKASASLPLPS
What is the function of this protein?
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group (Probable).  Possesses cytokinin oxidase activity toward trans-zeatin (tZ) and N6-(2-isopentenyl)adenine (2iP) in vitro (PubMed:31235564).  Functions as a primary strigolactone-responsive gene to regulate rice tillering, plant height, and panicle size, likely via a secondary response gene, RR5, which encodes a cytokinin-inducible rice type-A response regulator that seems to act as negative regulator of the cytokinin signaling (PubMed:31235564).
What are the official names of this protein?
Cytokinin dehydrogenase 9, Cytokinin oxidase 9, OsCKX9.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: LOLB_PSET1
Sequence: MESKEQHLIRQYFILAMFFLFLAGCAQKRSLETTTYENWKTHLAEQSIWQVEGKLAFISPDERQSANLNWQQSQNNNNLVLTTFIGTRILSLKQTANTAELNYDGEQYFDTNATALLKRLTGFALPVNNADSWLKGTIDDQTLKVDQLGRAKSVLWFDSTGKKWQIEYASFVQKSGYWLPSRLTLTHQKIKIKIQLYDWQFN
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: BGLH_ASPFN
Sequence: MALDIDYVLSHISQEDKIALLAGIDFWHTHPIPELNVPSIRSTDGPNGIRGTKFFAGVPAACLPCGTALASTWDQNLLREVGVLIGKECLAKGAHCWLGPTINMPRSPLGGRGFESFAEDPHLAGAMAASMITGCESTGVISAVKHFVGNDQEHERRAVDVLVTQRALREIYLRPFQIVARDAGPGALMTSYNKINGKHVVESKEMLDMVRQEWKWNPLIMSDWLGTYTTIDSMNAGLDLEMPGPSRYRGRYVESALQARLIKESTIDSRARKVLEFVQQASRAPVSAVETGRDYPEDRALNRNLCANSIVLLKNQNDILPLPKTIKKIALVGSHVRTPAISGGGSASLEPYYTVSLYDAVSEALPHTEILYEVGAYAHKMLPVIDRLLTNAVMHFYNEPVGTERILRATQRMSKTAFQLMDFNAPELNRGLFYATLTGDFTPDVSGVWDFGLTVFGTGLLYVDDELVVDNTTHQTRGTAFFGKGTVQELGSKTLNAEQTYKIRIEYGSANTSPMKAIGVVHFGGGAAHLGACLHVDSAEMVRSAVKAAAEADYTILCTGLNHEWESEGFDRSHMDLPPGIDALITSVLDVAANKTVIVNQSGTPVTMPWADRARGIVQAWYGGNETGHGIADVIFGDVNPSGKLPLSWPVDVKHNPAYLNYASVGGRVLYGEDVYVGYRYYEKVGREVLFPFGHGLSYTTFTVSPDVVFSQEVFRPEEPPTAAVKIKNTGKVAGAQVLQLYISAPHSPTPRPTKELHGFTKVLLQPGEERVAHIRMDKYATNFWDEIEGMWKSEEGIYEALIGTSSQNILAKGTFRVDRTRYWLGL
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase H, Beta-D-glucoside glucohydrolase H, Cellobiase H, Gentiobiase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_BDEBA
Sequence: MRADGRLFDQLRNIKITPNVSEYAEGSAIVEFGRTKVLCTATYESKAPSWLLGTGAGWITAEYGMLPRSTHTRIRRDKSMTGGRTQEISRLIGRSLRAAVDLKQLGEKQIIIDCDVLNADGGTRTASVTGGFVALALALKKLHAVSEIKTLPLINYVSAISVGLHEGQILLDLNYDEDSAIGTDMNFVMTDKGQFVEVQGTAEHVPFTRDQLFKMMDVAEKGCRELFIHQASVMGEIYKIAGA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL2_METMP
Sequence: MGKRLISQNRGRGTPKYRSPTHKRKGAVKYRSYDEMEKDGKILGTVIDILHDPGRSAPVAKVKFANDEERLVLIPEGIQVGEEIECGISAEIKPGNVLPLGEIPEGIPVYNIETIPGDGGKLVRSGGCYAHVISHDVGKTIVRLPSGFSKVLNPACRATVGVVAGGGRKEKPFVKAGKKYHSLSAKAVAWPKVRGVAMNAVDHPYGGGRHQHIGKPSSVSRHTSPGRKVGHIASRRTGKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.