PharMolix/UniProtQA huggingface dataset:
Protein: GNAI1_XENLA
Sequence: MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDPSRADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDGGVQACFNRSREYQLNDSAAYYLNDLDRIAQNSYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKRSPLTICYPEYPGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades.  The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state.  Signaling by an activated GPCR promotes GDP release and GTP binding.  The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal.  Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (By similarity).  Signaling is mediated via effector proteins, such as adenylate cyclase.  Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels (By similarity).  Required for cortical dynein-dynactin complex recruitment during metaphase (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein G(i) subunit alpha-1, Adenylate cyclase-inhibiting G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cell cortex. Membrane; Lipid-anchor.
Protein: RL33A_YEAST
Sequence: MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAYVYRASKEVRGSKIRVMWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L33-A, L37, Large ribosomal subunit protein eL33-A, RP47, YL37.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_DEIGD
Sequence: MRTAVIQFPGSNCDADALHAARLTLDPDAGFVWHTETALPRGTELVFLPGGFSYGDHLRSGAIAARSPIMAAVKAHAERGGFVLGVCNGFQVLTEAGLLPGALSRNRDLHFRCAPVHLRVENAQTVFTRAYQPGQILEIPIAHGEGNYYADPETIARLEAEGRVVFRYVDNPNGSLNDIAGIVNERGNVLGMMPHPERAVEALLGSEDGRGIFESLKGALVQ
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y249_PSE14
Sequence: MLSWAITFLIIAIVAAVLGFGGIAGTATGIAKILFVVFLVMFVVSFFFGRRGRG
What are the official names of this protein?
UPF0391 membrane protein PSPPH_0249.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RTCB_PLAF7
Sequence: MKGIPKRPISNYIEKTNETNLYKIRKGLVNEMNVEGHIYVNEKLKTLLDEEIATYELNKNSTFLPAVMQIANVSTLPGIVKASIALPDVHAGYGFSIGNVAAFDMDNEKAIVSPGGVGFDINCGVRLIRTNLFYEDIKPKQEELTQLLFNHIPVGVGSQGFILCNQENLDDALCLGMDWCVKEGYSWIEDKLNCEDNGRSLYADSNFVSIRAKKRGITQMGTLGAGNHYAEIQIVDQIYDKKSAKLMGIEKKNQVCIMIHSGSRGLGHQIATDALIDMEKSMNKYKINVIDKQLACTPIHSKEGQNYLKAMGSACNFAWINRSSMTFLARQAFSKIFNQSPDDLDMHVIYDVSHNIAKIEEHYIDGKIKKLLVHRKGSTRAFPPFHPLVPLDYQYCGQPILIGGTMGTYSYVLTGNEKAMQATFGSTCHGAGRALSRNKSRNTLSYLDVLNKLKEQNISIRVASPKLIMEEAPESYKNVCDVVQTCHDAGISNKCFRLKPVAVIKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: Y816_CALBD
Sequence: MAGHSKWANIKHKKEKTDAQKGKLFTKLGRELMVVAKMYGPDPETNPKLRDVIAKAKANNMPMDKIMGFIKRAAGEIDTTGYEDITYEGYGPGGVAVIVEAMTNNRNRTAGELRHIFDKNGGNLGQTGCVSWMFSRKGVIVIEKESFPDEDFVMEKALEYGAEDFTSENGIYEIITSPEDFSKVREGLEKEGFTFIRAQIEMIPQTYVKLSSEDAQKMRRLIDMLEDNDDVKEVYHNWEEDEE
What are the official names of this protein?
Probable transcriptional regulatory protein Athe_0816.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCH1_CAPAN
Sequence: MAAEISISASSRAICLQRNPFPAPKYFATAPPLLFFSPLTCNLDAILRSRRKPRLAACFVLKDDKLYTAQSGKQSDTEAIGDEIEVETNEEKSLAVRLAEKFARKKSERFTYLVAAVMSSLGITSMAVISVYYRFSWQMEGGEMPFSEMFCTFALAFGAAIGMEYWARWAHRALWHASLWHMHESHHRPREGPFELNDIFAIINAVPAIALLSFGFNHKGLIPGLCFGAGLGITVFGMAYMFVHDGLVHKRFPVGPIANVPYFQRVAAAHQLHHSDKFDGVPYGLFLGPKELEEVGVLEELEKEVNRRIKSSKRL
What is the function of this protein?
Nonheme diiron monooxygenase involved in the biosynthesis of xanthophylls.  Specific for beta-ring hydroxylations of beta-carotene.  Produces beta-cryptoxanthin and zeaxanthin.  Uses ferredoxin as an electron donor.
What are the official names of this protein?
Beta-carotene hydroxylase 1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: AAEB_ECO8A
Sequence: MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVHRLAGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAY_HALHL
Sequence: MLYHLAMVLETFYSGFNVFQYITFRTILGVLTALGIALMIGPAVIQRLVLHQVGQQVRDDGPETHLEKAGTPTMGGALILVAIAVSTLLWADLTNRYVWVVLLVTLAFGLIGGVDDALKLARQDSQGLRARTKFSLQVLAALAASTFLFATATDPVETSLVLPLVKEWVFPLGLGFIALATLVIVGSSNAVNLTDGLDGLAIMPTVLVATGLAVFAYASGHHVFADYLGIPSVPGVGELVIFCGAIVGAGLGFLWYNTYPAQVFMGDVGALALGAALGVVAVAVRQEIVLFIMGGIFVMETVSVMIQVLSYKLTGRRVFRMAPLHHHYELKGWPEPRVIVRFWIITVVLVLIGLAMLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ECFA1_STRA1
Sequence: MTNIITVNNLFFKYDSNQTHYQLENVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGQELTEDNVWELRHKIGMVFQNPDNQFVGATVEDDVAFGLENKGIPLKDMKERVDQALDLVGMSEFKMREPARLSGGQKQRVAIAGAVAMRPQVIILDEATSMLDPEGRLELIRTIRAIRQKYNLTVISITHDLDEVALSDRVIVMKNGKVESTSTPKALFGRGNRLISLGLDVPFTSRLMAELAANGLDIGTEYLTEKELEEQLWELNLKM
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL9_AMOA5
Sequence: MEIILKQDFKGLGYKNEIVKVKPGYARNYLIPQGFALVANETNKKIAQENAKQMAHKMAKRKQDAESIANRLSQLAIKIKAKVGEKGKIFGAITPIQIADALKEQTGYIADRRDISFEKPIKTLGTHKAIIKLHKEVVLTLSFEVIAEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: CBID_METB6
Sequence: MRDPVTGFVYPAAWVEKVSDPAGLEKVRGGSAVLTSSGTVLLRGYTTGTTAAAACKAAILSLAGDISRVTIQLPCGLSADLPVKARAGHASCRKYAGDYPSDVTAGIEFIADAAVAQKGILLVPGPGIGHFVRDTPRYKKREPAISTAPLACILSSMEEALGATGLSGATVTLSIPEGRTIADQTLNPRIGIEGGISVLGSTGLVEPWDDHLEDSVIARVAGATDPVITTGRVGLRYARLLFPDREVVLAGGKIKGALAAAKGEVTLCGLPALILKYIEPHILDKTGYATVEELAASPSFPSVALPILVAYKKKHPRVRVVLVNREGTVIAESP
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: MIC60_KLULA
Sequence: MFRASKALGQRFASTNVPVKTARPFRNFLWKLGAATTVFYVGGVALSTYNYQFAELFTDNVPLAEELVQLVESYNDGTLNAPQLSLDEIRKKFGSITRKVQSVPHLGSTSSTVTESQSIASGSGSTAAAATTGTDSNSVVLSSVPPVGSVLLRLPHLKLDDDSNSFNNKSFVESFNKQVDSLNEKEFILPENAVESFLESYHGLSSQLNELNRDLADQLNSQLGQLSAELKQSVESDKVKEIESNKLQLMQQFEKDLSNLKVEFEQKFDSQLQSSLKANEQAMLAKHKNELAMLSIKQVQEFNKIISNKIENERNGRLKNLDELNGSVKTVSDSLAALEETLLRSECVNQLTNLVSSIKFKLNLDNTPSLDISKDLQKLTTLVNILPGKPNKCDAKEPQLIDVVVNELNSLTSAKENKQILSNEQLLNRWGLLQDKIREASLLPPNAGFLGHVSAKFFSLFLFNKSGISNENDIDSVISRVTENIKLNRLDKAVEDVVQLQGWSRLEADDWLQAARSKLELETLVDVVDHEIKTL
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: Y544_PROM5
Sequence: MAENFSFDVVSDFDRQELVNALDQVKREISQRYDLKGTETILELEKENIFITTNSELTLNSVIDIIRQKAIKRKLSLKIFEYKSIEAVSGNKVKQTITLKKGLNQEIAKKISKNLRDEIKKINVSINGETLRVMSKSKNDLQLAIKLLENLEETYKIPLQANNYR
What are the official names of this protein?
UPF0234 protein P9515_05441.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: SOX12_HUMAN
Sequence: MVQQRGARAKRDGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAAPEDDDEDDDEELLEVRLVETPGRELWRMVPAGRAARGQAERAQGPSGEGAAAAAAASPTPSEDEEPEEEEEEAAAAEEGEEETVASGEESLGFLSRLPPGPAGLDCSALDRDPDLQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY
What is the function of this protein?
Transcription factor that binds to DNA at the consensus sequence 5'-ACCAAAG-3' (By similarity).  Acts as a transcriptional activator (By similarity).  Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity).  Involved in the differentiation of naive CD4-positive T-cells into peripherally induced regulatory T (pT reg) cells under inflammatory conditions (By similarity).  Binds to the promoter region of the FOXP3 gene and promotes its transcription, and might thereby contribute to pT reg cell differentiation in the spleen and lymph nodes during inflammation (By similarity).  Plays a redundant role with SOX4 and SOX11 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity).
What are the official names of this protein?
Transcription factor SOX-12, Protein SOX-22.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS10_PSEPW
Sequence: MQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVSPHVNKDARDQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: Y2083_MYCTO
Sequence: MTSIESHPEQYWAAAGRPGPVPLALGPVHPGGPTLIDLLMALFGLSTNADLGGANADIEGDDTDRRAHAADAARKFSANEANAAEQMQGVGAQGMAQMASGIGGALSGALGGVMGPLTQLPQQAMQAGQGAMQPLMSAMQQAQGADGLAAVDGARLLDSIGGEPGLGSGAGGGDVGGGGAGGTTPTGYLGPPPVPTSSPPTTPAGAPTKSATMPPPGGASPASAHMGAAGMPMVPPGAMGARGEGSGQEKPVEKRVTAPAVPNGQPVKGRLTVPPSAPTTKPTDGKPVVRRRILLPEHKDFGRIAPDEKTDAGE
What are the official names of this protein?
Uncharacterized protein MT2145.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCAP_I03A1
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVSGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYRRRDGKWVRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVVPRGQLSTRGVQIASNENMEAMDSNTLELRSRYWAIRTRSGGNTNQQKASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMNNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: NDUBA_GORGO
Sequence: MPDSWDKDVYPEPPRRTPVLPNPIVYMMKAFDLIVDRPVTLVREFIERQHAKNRYYYYHRQYRRVPDITECKEEDIMCVYEAEMQWRRDYKVDQEIINIMQDRLKACQQREGQNYQQNCIKEVEQFTQVAKAYQDRYQDLGAYYSARKCLAKQRQRMLQERKAAKEAAAATS
What is the function of this protein?
Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I.  Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10, Complex I-PDSW, CI-PDSW, NADH-ubiquinone oxidoreductase PDSW subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB10 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ACCD_BURO1
Sequence: MSWLDKLLPPKIKQTDPKSRKGIPEGLWVKCPSCEAVLYRNDVDANLHVCPKCDHHMRIGARERLDGLLDPEGRYEIGQEIVPVDTLKFKDSRKYPDRLKEAMDETGETDAMVVMGGAIHTLPVVAACFEFSFMGGSMGSVVGERFARGAQNALEQHVPFICFTASGGARMQESLLSLMQMAKTTAMLTKLAEAKLPFISVLTDPTMGGVSASFAFLGDVVIAEPKALIGFAGPRVIEQTVREKLPEGFQRAEFLLKTGAIDMIVDRRKMRDEIAQLLALLQRQPADALA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
Protein: DNLJ_YERPA
Sequence: MESIIQQINQLRTSLRHHEHQYHVLDAPEIPDAEYDRMMQQLRDLEAQHPELVTNDSPTQRVGAAPLDAFEQVKHEVPMLSLDNVFDEESYLAFDKRVHDRLKTAEPLTFCCELKLDGLAVSLLYENGELVRAATRGDGTTGENITANVRTIRAIPLRLHGDNVPRRVEVRGEVFMPQAGFEQLNEEARRKGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGLLDGGELPRSHIQCLMQFKAWGLPVSERVKLCTGSDQVIAFYRQIEQDRAGLGFDIDGVVIKVDDLALQEQLGFVARAPRWATAFKFPAQEQITQVREVEFQVGRTGAITPVARLEPVQVAGVIVSNATLHNADEIERLGLRIGDTVIVRRAGDVIPQVVGVVMEQRPDDTKEITFPSQCPVCGSDIERVEGEAVARCTGGLFCAAQRKEALKHFVSRRALDVDGMGDKIIEQLVEKQYVENPADLFQLTAGKLTGLDRMGPKSAQNLIAALEKAKQTTFARFLYALGIREVGEATAANLAAHFRTLDNLRAADIETLKSVPDVGEVVAKHVMNFLSEEHNQKVIEELEKVVSWPEPQQIVVEESDSPFAGKTVVLTGSLTILSRDEAKDRLTALGAKVSGSVSKKTHLVIAGEAAGSKLAKAQELGIKVIDEAEMIRLLGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MURD_RHIEC
Sequence: MIPVTTLKDRKVALFGLGGSGFATARALIAGGAEVTAWDDNPDSVAKASAEGIRTEDLHGIDWSQQALFVLSPGVPLTHPKPHWTVDLARAAGVDIVGDVELFVRERRAHAPDCPFIAITGTNGKSTTTALIAHILKSAGYDTQLGGNIGTAVLTLDPPKAGRYYVVECSSYQIDLAPTLNPSAGILLNLTPDHLDRHGTMQHYADVKERLVAGSDVAIVGIDDSHSALIADRVERAGVKVVRISRRNAVASGIYAEGIRLVQAVGGAMLPFADLDGIQTLRGSHNAQNAAAAVAACLAVGVSADAIRAGLASFPGLKHRMQPVGKRGRVVFVNDSKATNADAAAPALSSYDRIYWIAGGLPKAGGITTLAPYFPRIAKAYLIGEAAAEFAATLGEAVPYEISGTLERAVAHAAADAERDEAAASAVMLSPACASFDQYRNFEVRGDAFVSHVAALDGMTMLIGPATGEK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.