PharMolix/UniProtQA huggingface dataset:
Protein: MINE_PROM9
Sequence: MMTLRDLINKLLGRETASANTARERLQLVLAHDRVDMSSLTTDLLDKMRKEILDVVAKYVEIDFEEVAVSLETEDRMTALVANLPIKRTISGEIKFKKNDKTDQADKDIKK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RL35_NAUPA
Sequence: MPKMKTNRGAAKRFKVKKSGKIKRGAAYRSHILTKKSQKRKRNLRAPKYVDSTNIKAVRELLAI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: NADD_CHLT3
Sequence: MKKIALFGGSFDPPHYGHFALCTLTRELFSPEKIILSISKNPLKGSANAPEAHQLAMAKLMAEELGKTGPVFEVSDWELRRAGFSYTIETLRHFHAIEPNAELLLCIGEDNYQIFEKWKAYQEILQLAHLVVFARSGTQGEQQSSRIIPPERYTWVQLDLPLSSSDLRREIAEGQDWQAKMPSSIAAHIAAHRLYQNEK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: MTNA_MICAE
Sequence: MTTNNAENNSIYPVRWQDNKVWLIDQTRLPMEYGEVEITSSEAMARAIETMIVRGAPAIGVAAAYGMVLGAQEIKTNQKEEFLADLTRIADRLAQTRPTAVNLFWAIERMLKVARESGPEVAIISKNLLETAHNIQKEDVETCRAIGHHGLLALPEQPEKLTILTHCNTGSLATASYGTALGVIRSAWTAGRLIQVYADETRPRLQGAKLTAWECAREGIPVTVITDSMAAHCMQQKLIDAVIVGADRIAANGDTANKIGTYSLAVVAKAHNLPFYVAAPLSTVDFSLKDGTGIPIEQRDSAEIYQVGTTTLCPRNVNFYNPAFDVTPAALITAIITEKGAVTPAELIFLQDS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: DHI2_HUMAN
Sequence: MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALAVLAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLPQELLQAYGKDYIEHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYPGQGLGLMYFIHYYLPEGLRRRFLQAFFISHCLPRALQPGQPGTTPPQDAAQDPNLSPGPSPAVAR
What is the function of this protein?
Catalyzes the conversion of biologically active 11beta-hydroxyglucocorticoids (11beta-hydroxysteroid) such as cortisol, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as cortisone, in the presence of NAD(+) (PubMed:7859916, PubMed:8538347, PubMed:10497248, PubMed:22796344, PubMed:27927697, PubMed:30902677, PubMed:33387577, PubMed:12788846, PubMed:17314322).  Functions as a dehydrogenase (oxidase), thereby decreasing the concentration of active glucocorticoids, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids (PubMed:7859916, PubMed:10497248, PubMed:33387577, PubMed:12788846, PubMed:17314322).  Plays an important role in maintaining glucocorticoids balance during preimplantation and protects the fetus from excessive maternal corticosterone exposure (By similarity).  Catalyzes the oxidation of 11beta-hydroxytestosterone (11beta,17beta-dihydroxyandrost-4-ene-3-one) to 11-ketotestosterone (17beta-hydroxyandrost-4-ene-3,11-dione), a major bioactive androgen (PubMed:22796344, PubMed:27927697).  Catalyzes the conversion of 11beta-hydroxyandrostenedione (11beta-hydroxyandrost-4-ene-3,17-dione) to 11-ketoandrostenedione (androst-4-ene-3,11,17-trione), which can be further metabolized to 11-ketotestosterone (PubMed:27927697).  Converts 7-beta-25-dihydroxycholesterol to 7-oxo-25-hydroxycholesterol in vitro (PubMed:30902677).  7-beta-25-dihydroxycholesterol (not 7-oxo-25-hydroxycholesterol) acts as ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (PubMed:30902677).  May protect ovulating oocytes and fertilizing spermatozoa from the adverse effects of cortisol (By similarity).
What are the official names of this protein?
11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, 11-beta-HSD2, 11-beta-hydroxysteroid dehydrogenase type II, 11-HSD type II, 11-beta-HSD type II, Corticosteroid 11-beta-dehydrogenase isozyme 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, Short chain dehydrogenase/reductase family 9C member 3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: GTR3_MOUSE
Sequence: MGTTKVTPSLVFAVTVATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGLLTALWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLINKKEEDQATEILQRLWGTSDVVQEIQEMKDESVRMSQEKQVTVLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDDYEAMSFVCIVAILIYVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIFAAFLIFFLIFTFFKVPETKGRTFEDIARAFEGQAHSGKGPAGVELNSMQPVKETPGNA
What is the function of this protein?
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane.  Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate.  Does not mediate fructose transport.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 3, Glucose transporter type 3, brain, GLUT-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Localized to densely spaced patches along neuronal processes.
Protein: MTM1_MOUSE
Sequence: MASASASKYNSHSLENESIKKVSQDGVSQDVSETVPRLPGELLITEKEVIYICPFNGPIKGRVYITNYRLYLRSLETDSALILDVPLGVISRIEKMGGATSRGENSYGLDITCKDLRNLRFALKQEGHSRRDMFEILVKHAFPLAHNLPLFAFVNEEKFNVDGWTVYNPVEEYRRQGLPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIHPENKMVIMRCSQPLVGMSGKRNKDDEKYLDVIRETNKQTSKLMIYDARPSVNAVANKATGGGYESDDAYQNSELSFLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKLVLTGAIQVADQVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRTIEGFEILVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEGFLITVLDHLYSCRFGTFLFNCDSARERQKLTERTVSLWSLINSNKDKFKNPFYTKEINRVLYPVASMRHLELWVNYYIRWNPRVKQQQPNPVEQRYMELLALRDDYIKRLEELQLANSAKLADAPASTSSSSQMVPHVQTHF
What is the function of this protein?
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2).  Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides.  Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome.  Plays a role in vacuolar formation and morphology (By similarity).  Regulates desmin intermediate filament assembly and architecture.  Plays a role in mitochondrial morphology and positioning (PubMed:21135508).  Required for skeletal muscle maintenance but not for myogenesis (PubMed:12391329).  In skeletal muscles, stabilizes MTMR12 protein levels (PubMed:23818870).
What are the official names of this protein?
Myotubularin, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Cell projection, filopodium. Cell projection, ruffle. Late endosome. Cytoplasm, myofibril, sarcomere. Note=Localizes as a dense cytoplasmic network. Also localizes to the plasma membrane, including plasma membrane extensions such as filopodia and ruffles. Predominantly located in the cytoplasm following interaction with MTMR12. Recruited to the late endosome following EGF stimulation (By similarity). In skeletal muscles, co-localizes with MTMR12 in the sarcomere (PubMed:23818870).
Protein: RL29_CLONN
Sequence: MRANELQELRVNTAQELSAKLNDLKAELFNLRFQLATGQLENPMRIRQVKKSIAQVKTILREKELKVIEQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: NU4LM_POTTR
Sequence: MSSINLNLIMAFSLALMGVLIYRSHLMSTLLCLEGMMLSLFILMALLISHFHMFSASMAPLILLVFSACEAGVGLALLVKTSNNYGNDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PRIB_SHEHH
Sequence: MTTNNLVLAGTITRSRQFDSPAGIAHTVVMLEHKSQRYEAGMLRNVYCQIQVVLSGEHFNSVSKNLKAGVEIQVEGFINLQQSRNGQNRLVLHAENVELKT
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: UTP25_LACTC
Sequence: MSSLKRSSSAIKGSNEYRSSKSGRKQLRTIRKASGPRRGLAEESANEENNGSETEAEDKLAAPELNEPAQDQRAGGEAYAALLTLLKAEHGGPARRKTKTDDKKTSADPTSNVKDEEESESRDNEDEEEDEDEEAAIENALMDEHTSGDEDDEGDDGSHQDDINGVTREGGDATELAAGFEEEDKPDTLEIHFNSVSEKDTNALDAAFKAKEVRYRSCKLHVDKNQEFIYSRPTLVNEPASAVSAPDGSQSLNSYFIKQRLKIQNDLLDSQDKLTPLQKQIVDPMFQYQDLLYEYEDYDKETEYRDLYALHVLNHIYKTRDRILKNNQRLQENPDQELLDQGFTRPKVLIVAPTRDAAYDILSKIIQKSGLDQVDKKAKFKDQFFQEALPPSYKPKSFQQLFKGNTNDFFVLGAKFTRKTIKLYSNFYQSDIIICSPLGIQLILENTDKKKRQDDFLSSIELLVVDQLHSIEFQNMLHLTSIFEHINKIPQQQHDADFSRIKMWYINDQAKLFRQTLIFTKFSSPFANSLINGKCRNYAGRWKNHRVIFPENSSLGQLGMRTRLIFQRFDLVGKSVSEEPDSRFKHFCSVIVPNIVKSTGYEDGILLYIPDYTDFVRVRNYLREKTTILFGDINEYSEQRQLTSNRAMFQQGRVKVLLYTERLHHFRRYEIKGVKTVIFYKPPTNPEFFEEVARYLGKSAFLGLADLNISVVRCLFSKLDGLSLERIVGTERAAVLTHGPNETYEFK
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PANC_STAA3
Sequence: MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITIVSVFVNPLQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDMYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRIEEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABCA6_DICDI
Sequence: MEFGRQLKTLLKKNLLLKGKSKCSICCEIVFPIVIIGVLFAILALIKVTNSDYNSIDVTTFSRRVGPENKLLYGSEGSLNNDQSGVIETMKEQVATARGLTVAEVQDFFMEINDRTLMESFFKNYSMMVYGGVWFNSSTNGGGGGNNNDPIAAGGQFGYNIRLDSDDTADTSETGKVDGGDSSIYLNDNFASIQVAMDQAIFGYFGLDMVLNISGRHYPDPYTELWQEWITGRDAIIKSAGSVFITAALMMFSFRLVTDVVIEKETKIVEAMRMMSLNSLAYFSSWIITSLITSLPVTLLIVVIFKGSQLIYSTSWGIVIITFVLYLITLLLLSFIFSIFFNNSKFCGLLSFVIVIAINICGIFVSKNEFSVSVKLLLSIFSPIAFSNSIYIMSVKDLTMILNLNWDYIVTENQSILMLGIDIIIYIILIWYFEKVIPGEYGTKEKFYFLFTKNYWFGKKRSIGEIDDIESTFDSEDVETIPLKVLKNSTISIRNLRKEFETGDGLRVAVNDLYLDMFEDQIHALLGPNGCGKSTTIGMLTGLISPTSGSAFIRGYDITSQMSKIRPYIGCCLQTDIIWSQLTVLEHLVIYASLKGVEGRNIQREAERMATEVGLAEKMNAPAGSLSGGQKRKLCLGIAFIGRSKIIFLDEVTSGMDPVSRRQVWDFLLKYKKGKTIILTTHYLEEADYLGDRIAIISQGKLRCDGTSLFLKNRFGQGYLLTCNKKLENASNGFNTNQVSEFIKNFIPGASILTDSGAELSYRLPTESLSNFPQFFTEFDLNLSKFSIQTYGISVTSLEEVFISLGQEDSKKLNNNANGNNEFNKQNEMESLKLAIATPSDGINQIQQFKGLLIKRIQQSKKDARSFFLSIILPMALIIGSIILYKSMNDQKQVLFYNNSTQPLTMSLSIYTDSDNTINVPMQLLNNELEWSNLFNNSPYFNKFKYINESINFNDYLIDNYKLSIGAINFTNQPISIDDNNNGQSTNCSYIAYYNSDYIHSFPIHVNLINDALLRKFKNISISVTSMPFDHILTAFEISSSDINASAIIYFVFILMAGFSLMAGSFAGSIAQERTNRVKRLLYVSGCKKHIYWLSNLVWDFFFAFIISILSCSILAGVIKGAFKEQFGSFLLCLILLSCAIIPLGYLMSYKFQTYGKAVGAITAILFVFGLVFTIASLNVRIQAVVNQNSTTQKVADIIDLIFSIISPIFALNRIVFILSGFPGSTRLGTFKVDNYWSFDYLGTPLIVLAGHAVLWNVWILLLDYVPQIKGFFKNPKNLPAPSPPQDEDYDVSQERRRLLNMRPSEEPIQFKNLHKLFPGSGKNPSKTAVYNSTLGIPRGQTFGLLGLNGGGKSTTLSMLSGEIVPSSGEISINGYDVITNREKALGNISMVFQFDALISLLSAREHLWLFSRIKGIKESQIENCVEAFIKMVDLTRIANSGCGGYSGGNKRKVSLSMAMLGNPSVCFLDEISCGCDAVVRRQLWDVISELGKDKSIILTSHSMSEVEALCSRITIMKEGKYTCLNTIQGVKNRFGAGYSIDVKFKKEYLETGIQTILQSIPNCTVLDQHDVMASFEVPNPPGNPIKLSNIFSILSNLPILDDYNVGQTSLESVFLKLTGANHDQRINLYD
What are the official names of this protein?
ABC transporter A family member 6, ABC transporter ABCA.6.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PCKA_SODGM
Sequence: MVSESITPQQWISYGITGYRELVYNPGYDQLFAEEIDPALSGFERGTLTQSGAVAVDTGIFTGRSPFDKYVVRDDKTRDTLWWSDQGKGANDNHPLDQQTWVHLKRRVGKQLSGKRLFVIDAFCGANEDSRLRVRFVTEVAWQAHFVKNMFIRPSDEELRDFEPDFVVLNGAKCTNPDWREQGLHSENFVAFNLTEGIQLIGGTWYGGEMKKGLFSVMNYLLPLKGIASMHCSANVGTDDDVALFFGLSGTGKTTLSTDPRRRLIGDDEHGWDDDGVFNFEGGCYAKTIRLSPEAEPEIYQAIRRNALLENVVVRADGSVDYDDGSKTENARVSYPIDHIDNIVKPVSRAGHATRVIFLTADAFGVLPPVASLSMEQAQYHFLSGFTAKLGGTERGVVAPVPTFSACFGAAFLSLHPTAYADVLAKRMHAAGARAYLVNTGWNGSGKRISLKDTRTIINAILRSDIDDAPTATLPVFNLTIPTALPGVNGAILDPRTTYASVDEWRAKADDLAQRFIDNFSKFTDTPAGVALVSAGPQR
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDC25_YEASX
Sequence: MSCTASYAGMTTPVKDKEGHGIPCLQPIDVVECTYQYFTKSRNKLSLRVGDLIYVLTKGSNGWWDGVLIRHSANNNNNNSLILDRGWFPPSFTRSILNELHGVPDIGNELEIFQAGLNLKLELSSNPVILSLEDFLDCCRDIEFKEQLAWSPTPVHERKGCCELLYYNQDLDVYCRTLPYLPQNQVETVNDYSSFPAISKIAGKKMPITSSPDLFYLNDCDVVYWYDLTRLVCHYVNLTERDLLANEREKFLTSLDLLTAQITYVYMLFRNLRLVEDSFKKTLKKLIYTLSRFSINANIWFHSTSFEEREAIASQKDPERRSPLLQSILGTFQKFHFLLRLLHFLSNPNELTILPQLTPRFFKDSFNTISWNNPFLRTVFNQHMSMTLPRQMIKAVAGASGIVAENIDEIPASKQGTFISSETSHHSPSAPFQRRRRGTIFSNVSGSSDESDTIWSKRKKPYPLNEETLSLVRARKKQLDGKLKQMIKSANEYLSNTANFSKMLNFEMNFKTYEEVSGTIPIIDILENLDLTIFLNLRELGDENRVFDEDVAIGDEDKEFLKHSLSSLSYILSDYFNMKQYFHDVVVKFIIVAQHLTLEDPFVFSPMQNDLPTGYYEPMKPSSLNLDNAKDKKNGSQNTDIQEEEDEYEPDPDSLILFHNLINQDSDFNDLKFFNLAHVFKKSCDDYFDVLKLAIEFVNQLILERENLLNYAARMMKNNITELLLRGEEGYGSYDGGETAEKSDTNAVYADSDTKDNDEWRDSQVKLPRYLQREYDSELIWGPIVRIKGGSKHALISYLTDNEKKDLFFNITFLITFRSIFTTTEFLSYLISQYNLDPPEDLCFEEYNEWVTKKLIPVKCRVVEIMTTFFKQYWFPGYDEPDLATLNLDYFAQVAIKENITGSVELLKEVNQKFKLGNIQEATAPMKTLDQQICQDHYSGTLYSTTESILAVDPVLFATQLTILEHEIYCEITIFDCLQKIWKNKYTKSYGASPGLNEFISFANKLTNFISYSVVKEADKSKRAKLLSHFIFIAEYCRKFNNFSSMTAIISALYSSPIYRLEKTWQAVIPQTRDLLQSLNKLMDPKKNFINYRNELKSLHSAPCVPFFGVYLSDLTFTDSGNPDYLVLEHGLKGVHDEKKYINFNKRSRLVDILQEIIYFKKTHYDFTKDRTVIECISNSLENIPHIEKQYQLSLIIEPKPRKKVVPNSNSNNKSQEKSRDDQTDEGKTSTKKDRFPKFQLHKTKKKAPKVSK
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP.
What are the official names of this protein?
Guanine nucleotide exchange factor SDC25.
Protein: S9AD_STAAM
Sequence: MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRINSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYPPKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLTDIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEHVTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN
What is the function of this protein?
Mediates bacterial resistance to the antibiotic spectinomycin but not streptomycin.
What are the official names of this protein?
Spectinomycin 9-adenylyltransferase, AAD(9).
Protein: Y671_STRPJ
Sequence: MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVPTQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR
What are the official names of this protein?
UPF0298 protein SPN23F06710.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_CHESB
Sequence: MVDINQIPTRRPFHRRRKTCPFSGANAPKIDYKDVKLLQRYISERGKIVPSRITAVSQKKQRELARAIKRARFLGLLPYVVK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: DF250_ARATH
Sequence: MKLAAIFLVSCVLLSLLPSLTIAEKRPWCPTRKQIFDGSCNRTDYTQCFNDLRNTWDDIGDLCPTDCTCTPQPQNKRLCYCRYLPCPST
What are the official names of this protein?
Defensin-like protein 250, S locus cysteine-rich-like protein 8, Protein SCRL8, SCR-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOG1_BOVIN
Sequence: MEPTRDNPLFGGAFSATLPPGAIDVSDLRPVPDHQEVFCHRVTDQSLIVELLELQAHVQGEEAARYHFEDVGGVQEARAVQVETVQPLVLEKLALRGCCQEAWILSGQQQVAKENQQVAKYVTLHQALLRLPQYQTDLLLTFNQPPPENRSSLGPENLSIPPWSLGDFEQLVTSLTLHDPNIFGPE
What is the function of this protein?
May regulate the intracellular trafficking of RAN.  Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1.  Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics.  Enhances the expression of SCN5A at the cell membrane in cardiomyocytes.
What are the official names of this protein?
Ran guanine nucleotide release factor, RanGNRF, Ran-binding protein MOG1.
What is the protein family that this protein belongs to?
Belongs to the MOG1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=May shuttle between the nucleus and cytoplasm.
Protein: SYC_SHIB3
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQTRAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_HAEIN
Sequence: MNIEKFTTKFQEALSERQSLAIGKDNQFIEPVHLLTALLNQQGGSIAPILTASGVNVALLRNELKTELNKLPQVIGNGGDVQLSRQLINLLNLCDKFAQQNQDKFISSELFLFAALEERGTISDILKKCGAKKEQISQAIQHIRGGQNVNDQNAEESRQALEKYTIDLTARAESGKLDPVIGRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLDMGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVDEPSVEDTIAILRGLKERYEIHHHVDITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASSIRMEIDSKPEPLDRLERRIIQLKLEQQALQKEEDEASRKRLEMLEKELAEKEREYAELEEVWKSEKATLSGSQHIKQELDTAKTELEQARRAGDLAKMSELQYGRIPDLEKQLEQAETSEGKEMTLLRYRVTDEEIAEVLSKATGIPVSKMMEGEKEKLLRMEDELHKRVIGQEEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLAKFLFDSEDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHADVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQGNKDESYSEMKALVMSVVSQHFRPEFINRIDETVVFHPLGKENIRAIASIQLERLAKRMETRGYELVFTDALLDFIGEVGYDPIYGARPLKRAIQQEIENSLAQQILSGALLPGKVVTIDYANAEVQARQ
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAS21_CAEEL
Sequence: MNYFITFFFMHIAVLNFYFRFSNGNKIVMRVGGSPETKRLERSKRQALRMDNEPRWPRGTINYFFDEQRFDENSRATVLRAMEKISNHTCIKFSPKDARIKLRIVSDKGCQAAIGRVGGDQQYLSFPTSCYSVGSASELIHVIGFLHSHQRADRDEYLKLNLQPWRLNDWFQTMQYKKYLDQWWIVPYDYGSIMQYHDSDNEYGPKNSKYFRTMGSQIPSYFDYLMINEYYQCSCEGEEQINCKNRGYPNPGNCSECNCPLESSEEWKNITLNLDAGYMSLQNGTKLHQIDFVFRYLSISAPANKTIEVDIREITGVECNYGCYIGGIEVKTHEDRRMTSPRLCCKNDNEIYKSRNNPTIVMAFNSEGLDKYNIFYRFTD
What is the function of this protein?
May lack metalloprotease activity.
What are the official names of this protein?
Zinc metalloproteinase-like protein nas-21, Nematode astacin 21.
What are the subcellular locations of this protein?
Secreted.
Protein: TMPSD_HUMAN
Sequence: MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMEVRSLQQDTAPSRLGTSSGGDPGGAPRL
What are the official names of this protein?
Transmembrane protease serine 13, Membrane-type mosaic serine protease, Mosaic serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.