PharMolix/UniProtQA huggingface dataset:
Protein: MCM8_RAT
Sequence: MSGAYRGRGFGRGRFQNWKRGRGGGNFSGRWRDRTDLSKAAGNHASEQASQPLLQQSTLDQFIPYKGWKLYFSEVYSNNSPLTEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTKDNEITNLIPDIENALRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEGLCNGGGTMVNVPHIYARVYNYEPLTHLKNIRATCYGKYISIRGTVVRVSNIKPLCTKMAFQCAACGEIQSFPLPDGKYNLPTKCPVPACRGRSFTPLRSSPLTVTMDWQLIKIQELMSDAQREAGRIPRTIECELVHDLVDSCVPGDTVTVTGIVKVSNSEEGSRSKNDKCMFLLYIEANSVSNSKGQKAQTAEDGCKHGTLMEFSLKDLYAIQEIQAEENLLKLIVNSLCPVIFGHELVKAGLMLALFGGSQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTATSSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQRAVSSATVSRVLSQDSNTSVLEVVSEKPLSERLKVAPGEKTDPIPHQLLRKYIGYARQYVHPRLSTEAAQALQDFYLELRKQSQRVGSSPITTRQLESLIRLTEARARLELREEATKEDAEDIIEIMKHSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNSIAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKIYQLQTM
What is the function of this protein?
Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR).  Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity.  Probably by regulating the localization of the MNR complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs.  The MCM8-MCM9 complex is dispensable for DNA replication and S phase progression.  However, may play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC).  Probably by regulating HR, plays a key role during gametogenesis.  Stabilizes MCM9 protein.
What are the official names of this protein?
DNA helicase MCM8, Minichromosome maintenance 8.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to nuclear foci. Localizes to double-stranded DNA breaks. Binds chromatin throughout the cell cycle.
Protein: RL29_EXISA
Sequence: MKATDLRQSTTEELNGKVGEWKEELFNLRFQLATGQLENPARIREVRKSIARAKTILRERELGINNG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL28_BACHK
Sequence: MARVCAITGRKARSGNSRSHAMNATKRKWGANLQKVRVRIDGKVQRVYVSARALKSGKIERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MSBA_VIBVY
Sequence: MSINTDESTWRTFKRLWTFIRLYKSGLAVAVVALIINAVSDTYMVSLLKPLLDEGFGSAESDFLRTLPLLVFGLMFIRGISSFVSTYCLSWVSGNVVMQVRRMVFNHYMQMPVSYFDKEKSGSLLSRITYDSEQVSAATSQALVSIVREGTSIIGLLVLMFYNSWQLSLVLILVAPVVAWAIGFVSKRFRKISKNMQTTMGIVTSSAEQMLKGHKVVLSYGGQEVEKSRFDVVSNQMRQQSMKLITAQAAANPIIQMIASIAIVVVLYLASVDTIKDQLTPGTFTVVFSAMFGLMRPLKALTNVTSQFQRGMAAAQTLFALVDLEPEKNTGTYSVERAKGEVNVKDISFTYEGAEKPALSHVSFDIPRGKTVALVGRSGSGKSTIANLFTRFYDVDSGEIQLDGVDVRDYELKNLRTQFALVSQNVHLFNDTIANNIAYAAGDKYSREDIERAAELAHAMEFISKMENGLDTVVGENGASLSGGQRQRVAIARALLRDAPVLILDEATSALDTESERAIQSALDELQKNKTVLVIAHRLSTIEKADQILVIDDGAVVERGSHSELIEKDGAYAQLHRIQFGEG
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RAD21_XENLA
Sequence: MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIICPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVSNINILQDNDFGDFGMDDREMMREGSAFEDDMLTTNASNLKLEPEQSTSQLNEKSNHLEYDDQYKDDNFGEGNEGGILDDKLLSNDAGGIFDDPPAMPEEGVAMPEQPVHDDLDDDDNVSMGAPDSPDSVDPVEPLPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNTRLLKLFTRCLTPLVLDDLRKRRKGGEADNLDEFLKEFENPEVPREELRPQDVIDQPILEEASHLQESLMEGSRTHLDDTIMPPPPPKQGVKRDSLQMEPEPMPMMQEAEPQIEMPPPPLPPPLELPPEEPQSISDLIPELNLLPEKEKEKDEEEEEEEEDTTGTEQDQEERRWNKRTQQMLHGLQRVLAKTGAESISLLDLCRNTNRKQAAAKFYSFLVLKKQQAIELTQREPYSDIVATPGPRFHTV
What is the function of this protein?
May promote apoptosis.
What are the official names of this protein?
Double-strand-break repair protein rad21 homolog, SCC1 homolog.
What is the protein family that this protein belongs to?
Belongs to the rad21 family.
What are the subcellular locations of this protein?
[Double-strand-break repair protein rad21 homolog]: Nucleus. Nucleus matrix. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=Associates with chromatin. Before prophase, scattered along chromosome arms. During prophase and prometaphase, most cohesins dissociate from the arms of condensing chromosome, possibly through Polo-like kinase PLK1/PLX1-catalyzed phosphorylation (PubMed:11931760). A small amount of cohesin remains in centromeric regions and is removed from chromosomes only at the onset of anaphase. At anaphase, cleavage by separase/ESPL1 leads to the dissociation of cohesin from chromosomes and chromosome separation (By similarity). SUBCELLULAR LOCATION: [64-kDa C-terminal product]: Cytoplasm, cytosol. Nucleus.
Protein: KUP_STRP8
Sequence: MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQGGVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWLIIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLFGIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENHRGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKHSGIELNPFFASVPSQLTVYVVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVTYPGANLGQLYIPVINWILFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLNYYLIKEGVKPFLAHLVMTFFALVEFIFFWASAVKFMHGGYVVVILALAIVFVMFIWHAGTRIVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDYMIDRSILYSILDKRPKRARVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVELYLGFRMPQAVPRYLRTIVHDLMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVTASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASNA_BACCQ
Sequence: MYQSLMTVRETQIAIKEVKTFFEDQLAKRLELFRVSAPLFVTKKSGLNDHLNGVERPIEFDMLHSGEELEIVHSLAKWKRFALHEYGYEAGEGLYTNMNAIRRDEELDATHSIYVDQWDWEKIVQKEWRTVDYLQKTVLTIYGIFKDLEDHLFEKYPFLGKYLPEEIVFVTSQELEDKYPELTPKDREHAIAKEHGAVFIIGIGDALRSGEKHDGRAADYDDWKLNGDILFWHPVLQSSFELSSMGIRVDSKSLDEQLTKTGEDYKREYDFHKGILEDVLPLTIGGGIGQSRMCMYFLRKAHIGEVQSSVWPDDLREACKKENIHLF
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_BACTN
Sequence: MTTNLNGTFAAVQAASRELALLSDDTINQILNAVADATIAETSFILSENEKDLARMDKSNPKYDRLKLTEERLKGIAADTRNVATLPSPLGRILKETSRPNGMKLTKVSVPFGVIGIIYEARPNVSFDVFSLCLKSGNACILKGGSDADDSNRAIISVIHKVLEKFHVNPHIVELLPADREATAALLNATGYVDLIIPRGSSNLINFVRENARIPVIETGAGICHTYFDEFGDTRKGADIIHNAKTRRVSVCNALDCTIIHEKRLGDLPALCDQLKESKVTIYADTQAYQALEGYYPAELLQPATPESFGTEFLDYKMAVKTVKSFEDALGHIQENSSRHSECIVTENKERATLFTKIVDAACVYTNVSTAFTDGAQFGLGAEIGISTQKLHARGPMGLEEITSYKWVIEGDGQTRW
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_ACAM1
Sequence: MKILVGNDDGIFAPGVRALANTLAPDHEVTVVCPDRERSATGHGLTIHQPIRAEQVQSMFVDQVTAWACSGTPADCIKLALGALLDSPPDFVLSGINQGPNLGTDVLYSGTVSAAMEGVIEGITSIAFSYSSFTDQQFQPAANFGQQLLEHLIQHPLSEPMLLNVNVPAVPADQIQGVALTRQGIRRYHDLFEKRIDPRGKTYYWLAGEVMEDLEDDRMADPFVLTDVQAIRQRCIAITPLQYNLTANNSLNPLLAWLTPLQKRQSVI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_ACIAD
Sequence: MPKLEAKKGLFQFYPHNLIWLGLSILAIIIDQWTKWIASTHLNYADPVPVLPFLNWTLLHNYGAAFSFLSDAGGWQHYLFTGLAGIVSIIFIFWLMRMPKNAMILPAAIALILGGALGNLIDRMTLGYVVDFIHIYYQNHHFPAFNIADSAITIGTILLLIDTFFLEKQRIQRAEVKHD
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEF_PSYA2
Sequence: MALLPILSYPDPRLRMIATPVKEVTAEIKTLITDMIETMYDAEGIGLAASQVDHHIQLIVMDLSEDKDSPRVFINPKVTPLVEEKQPYEEGCLSVPDVYDKVERPNKVRIEAIDQNGNAIDEEVEGLLAVCIQHEIDHLNGVIFVDYLSRLKQTRARDKVRKVLKIREKQGEQVAEKEPQPANS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: YUC8_ORYSI
Sequence: MQGQQKQNAGGGGGDNASPCIVLDGPIIVGAGPSGLAVAATLRQHGAPFTVVERSGGVADLWTNRTYDRLRLHLPKVFCELPHVAFPPDFPTYPTKHDFLRYLHSYAARFAIAPLLRRTVTRAWYDHPASLWRVTTTTTSSSATSVITEYASPWLVVASGENAEVVVPKVKGRERFAGEALHSSEYRSGERFRGMRVLVVGCGNSGMEMCLDLCEHGAMPFMSVRSGVHVLPREMFGASTFGIAMKLLRWLPIKMVDRFLLLVARMVLGDTEKYGLKRPKLGPLEIKNITGKSPVLDVGAWSLIKSGNIKIVPEVESFSGNGARFVDGNEMAFDAVIFATGYRSNVPSWLQEDGELFTEEGKLRSSGSSSEWRWRGPNGLYCVGFSGRGLLGAGADALRAAADIAGRWQETQQAAANISSV
What is the function of this protein?
Involved in auxin biosynthesis (PubMed:24371168).  Converts the indole-3-pyruvic acid (IPA) produced by the TAA family to indole-3-acetic acid (IAA) (By similarity).  Seems not able to use tryptamine (TAM) as substrate (By similarity).  Probably responsible for auxin biosynthesis in leaves and involved in the regulation of lateral leaf growth (Ref. 3).  Required for maintaining water homeostasis and an appropriate root to shoot ratio (By similarity).  Required for the inhibition of root growth by ethylene in etiolated seedlings (By similarity).  Functions downstream of the ethylene-response transcription factor EIL1 (By similarity).
What are the official names of this protein?
Indole-3-pyruvate monooxygenase YUCCA8, OsYUCCA8, Flavin-containing monooxygenase YUCCA8, OsFMOt, Protein CONSTITUTIVELY WILTED 1, OsCOW1, Protein NARROW LEAF 7, Protein RICE ETHYLENE-INSENSITIVE 7.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: MO4_MOROL
Sequence: NRLCCSQYGFCGTTSEYCSRVSGCQS
What is the function of this protein?
Chitin-binding protein which functions in defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Morintide mO4, Morintide hevein-like peptide 4, Mo-HLP4.
Protein: GDPP1_XENLA
Sequence: MEEEHINQRPSATVEEYSYSEADFVFSGLSWKERRQYAEDTSFLSPFDKALQSKWEQKMNEGLFRYPLRNLQTKILPGSLSYVAQLNIQRSINRRKPEDIWSIQQKFNPNQFNYNKIKPEEIVFQMIRSETEHCVDSDKVHGSSVNGMGTSDCKSGSTHQRCCILECKGGCTLVVINVSPLEFGHVLFMPDPSLCLPQILTEDLMLFGLESVLLSAHPGFRVGFNSLGGFASVNHLHLHGFYLDHDLFIESSSSKPLCPEMNFHLITHFPAPSFLFYTDGRNLKSTAQNICKVTDFLVAKNIAHNLFITRGSNPDTGNGSEGRNGIRVNIWARKPSFGAKEVSAFNVALCELAGHLPVKNQEDFNSITEDSVIDIIHNCLLADDEFTQLSLDLVEYLRK
What is the function of this protein?
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
What are the official names of this protein?
GDP-D-glucose phosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the GDPGP1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_LEPBJ
Sequence: MISGLKGTLKKLEVGYAHIETGGITYEVTISFKTYLELKSLPSHNEVQFQIFHAMNERGQKLFGFLTEQDKEFFKVIKGLQGIGELTALKILSFFSAEELYRIAQSGEAKELEKIPKVKGKTSEKIFFEVKQNLKKLELFLSGTSKEPSISLSSFSETPEEAALSRKREIAILGLVQLGFEEKTASKEVDKILKSSSPTDPGEIIREILKSL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RSMH_SYNE7
Sequence: MLADSSQPSSFHHVTVLQRELVEGLLPDRGGWFLDATLGGGGHSELLLSEWPNTQVIGLDRDPAAIAASQTRLQLYSDRVQFQHVNFANYQPGDRRFQGIMADLGVSSPQLDEAERGFSFRQDAPLDMRMDPTAELTAAAIVNEWDETDLANLIYQYGEERLSRRIARRIVEQRPFERTLELSEAIAGAVPRSYRYGRIHPATRTFQALRIAVNGELDALQTFLDRAPDWLAPGGRIALISFHSLEDRIIKHALRGDDRLTVITRKPLLPSEAEIESNPRSRSAKLRIAERVLPES
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VHED_BPR06
Sequence: MFKRKSTAELAAQMAKLNGNKGFSSEDKGEWKLKLDNAGNGQAVIRF
What is the function of this protein?
Binds preferentially to single-stranded DNA and therefore, destabilizes double-stranded DNA.  It is involved in DNA replication, repair and recombination.  Binds ss-DNA as the replication fork advances and stimulates the replisome processivity and accuracy.
What are the official names of this protein?
Single-stranded DNA-binding protein, Gp32, Helix-destabilizing protein.
Protein: CAPPA_PYRAE
Sequence: MYIPCLMCTQHPDSTVKITAGEEVDEAVVAFLAYGCDEVMVDYEGKATPYSQPRDVASKALALGLPLGERFFITPRVPNPRLEDFERSMLSLEAAVLANSYSQRAAGVQAVKWVVLPMTEDVETMAFVYKALDMKARDLAELNAVKRDSSIELIPLVEDAMRQIKIESFIKALFRTAAQSGRILEHMRIFLGISDSAVRHGHMASALAMVKALGQISEINRDGEFKISPIVGMGSPPFRGGLNNPHLAVPEAAQYAGYKTATIQSAVRYDVSYAEYQKVREAILSVYTPRRLHVEEAWITKASELYREAIRPYIGKIAELANAIPSTRDRVSWREYGRVIEGVEWRVPRAIVYTATWYFAGVPPTLLDARFIAWAYKNDLLDDVLRALPATVEEWKFESRFYSRERAEKTLGGEIVKDIDNAFDILGIKPEPDRTYITLLNSADTQPHAIALGRIRGFLG
What is the function of this protein?
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 2 family.
Protein: UBP26_MOUSE
Sequence: MEPILINAQVQMWSAKAGMSKSRNALIETCVGKREVKLILYFSTGKIKTLQLHDNIKSVVLQTYGEDQNYLHLTFKNNDFLFVEKLTTTDARRLKRFLDKTSQGSIRPARSDERCGEPSTSAQELNGSGSSCETNSECFESPKESEMCMFRELSLLPSSSTFLHNVGLLENQFIKRKRFFSDLAKNEKQSNLKDSIRDFEANLVVCISNEKGKERNVREVDISKPGFGFPFETNYPEDSGVDVRDLNDLITKLFSPVLLETHCIENGLEWHEYMKTYLLYPEKLWQGLPNVGNTCYINVVLQSLCSIPLFINDLFNQGFPWIKAPKDDFNMLLMQLLVLKDIYNARFRQKLLIGITKALPIFGEIFAVDRQNDAHEFLSLCLVQLKETFQRVTMMWQSENDSGDFYLLKDIFADYATINKMPVCPVTNNFEFELLSSIFCKACGLTLFKGEPSRYLSINIPQGGKDMSIQSTLDLFFSAEELEHRCEKCLYNKSVSFHRFGRLPRVIIVHLKRYHFNESWVMKKDERPILVSKYLRLSCHCSKSTKPPPPLRPGEHVKNLDLLKPLEVLGSEILKLPFNSVRTSRSKGFETINITSNRESEAQSGKRVSEVLSGKVQQENSGKGDTAHIVGSELTKETEKLKKHEEEHRPSDLDSGSIREAQKYQQAEKCNEGRSDKQISLEALTQSRPKPISQEQTENLGKTTLSHTQDSSQSSQSSSDSSKSSRCSDDLDKKAKPTRKVDPTKLNKKEDNVYRLVNIINHIGNSPNGGHYINDAFDFKRQSWFTYSDLHVTRTQEDFVYRGRSSTGYVFFYMHNDIFEELLAKETQSTSTSKG
What is the function of this protein?
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.  Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 26, Deubiquitinating enzyme 26, Ubiquitin thioesterase 26, Ubiquitin-specific-processing protease 26.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLB4_SCHPO
Sequence: MYVNYIGLFAFVQISLTLAYPPGRVEISEIYDFEESSSYKGQDIDTSVLYTLSKRKPALVKRSTDASYAPFNVTCSNDNLLRPASEGLNEGEQSYINKRISKVNSELRSFISKTGLNVDLDKVVNSSDGPRLGIAFSGGGLRAMVNGGGAFNAFDSRFESDSPLSGLLQSAMYISGLSGGSWLVGSVAINNFTNITYLRDNVWNLEHSVFAPHGDNVIENLNYYNDLRKEIDQKKHAGFDCSLTDLWGRALSRKLVDAERGGPGITYSSMRNQSWFQNADYPYPIIVADSRLEEETAIPANTSIFEFTAYEFGTWDNGIKAFIPMEYVGTHLLDGVPPDKSCIHNYDNAGFVMGTSATLFNSFLLDWNENVKKNDTYYDILHAILEDLSKHQDDIAPYPNPYQNYTTSNTSVVNAFEPYDTIDLVDGGEDRENIPLWPLLHPQRFVDVVFAIDSTYNDPYGWPLGSSIVATYERVVTFNANKSVDVRGFPYIPDENTIISLGLNTRPTFFGCDGKNTTAGNHDVDNNTPPLLVYFPNYPWTYYSNISTFTMSMDDKMANGILENAFMSTTQNNNESFAVCLACAIIQRSLERKKLSTPTQCSSCFQEYCWDGTLATSTASVYDPTVMSAATTSRAPSGTTSGTASSTTSSSVASATPTHKHWWDSIFEAKENP
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids.
What are the official names of this protein?
Putative lysophospholipase SPAC977.09c, Phospholipase B.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DBP6_CANGA
Sequence: MFAARFDPTKVVREEPKIIPQKRAIPDDVESSDSDQDIEDGVEVGAVSKEQSGTDVTTTRAVDGKSESDSESESESESDSDDEMNFDMGGSSSSSDDDEVSSKDADVDDDGKHTSVLSRFKKTLSIQDKISALEEANTQDILEDGEAHDLAQIPQPAVVRDKKLQVKDISEMKNTAFRDTRKVHYDNSMTKSFEEYSDDLTPKLLNNIEKYFSKSTFPIQTAMLDQYLKLINFTLKTSKKNFTRRIGDILVNASTGSGKTLAYSIPIIQTLSSRTVNKLRVLIILPTKLLINQVFQTMSQLAEGTSLVITVSKLENSFNEEHKRLLKTEPDIFITTPGRLVDHLTNSSISLRNLKFLVLDEADRLLNQSFQNWIPEVMSKFKSDKFDQMPGSIIKMVFSATLTTNTEKLNDLQLYNPTLFATDSVKLYNLPPTLQEYQLQIPSAKSVYKPLYLLKLLEQLSGGKTLVFVRSNESSLKLEVLLKSLIKGHMTTLQIVVHSINSNNSKAENRRLVTDFTKESLPNQTNVLITTDLMSRGIDIENIANVINYDVPISSQQYVHRCGRTARANKDGKAYNMLVGKGEAQFWKDSIDEDISRDVSGCKPISYNDSYNKVHGDENARTSEPTRDLFTSIDSETSDKYNEILKNLTQK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LEUD_METC4
Sequence: MEKFTTLEGVAAPMRIINIDTDRIIPKQYLKTIKRTGLGQGLFSEMRYNDDGSENPDFVLNQPAYRHAKTLVVGDNFGCGSSREHAPWALADFGIRCVISTSFADIFFNNCAKNGILAIVVSPEDLEKLFQDAERGANATLTIDLAAQTIKGPDGGTLHFDIDEGRKHNLLNGLDEIGLTLDQKAPAIDAYEAKLAQREWA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CSPA_RICFE
Sequence: MATNIVGKVKWYNSTKNFGFIEQENGGKDVFVHKSAVDAAGLHSLEEGQYVIFDLEEKQGKAYAVNLRIK
What are the official names of this protein?
Cold shock-like protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH1_HALH5
Sequence: MTRAGILGIGSYVGEHVVTNKDFEKRIDTSDEWIRTRTGIEERRFAPDNVDTSDMAYEASVKALKAAGVSAEEIDLILVATVTPDMPFPTVSTLVQQRLGAKKAAAMDISAACAGFIYGLATGQQFIENGGYKHVLVIGVEKLSKITDMTDRNTAVLFGDGAGAAVMGAVSEDRGILAYELGADGEGAMHINQKGEYIQMNGREVFKFAVRQMGESALSVLEKAGLSKEDVDFLIPHQANIRIMEASRERLELPVEKMSTTVKKYGNTSSASIPMAMVDELKDGKIKDGDLLVLVGFGAGLVWGSLALRWGR
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III 1, Beta-ketoacyl-ACP synthase III 1, KAS III 1, 3-oxoacyl-[acyl-carrier-protein] synthase 3 1, 3-oxoacyl-[acyl-carrier-protein] synthase III 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
Protein: SEN2_NEUCR
Sequence: MAENMTIATMAQPSESPSKSGEEAPASTNPAATSAPPRPPRVPYHQIYKLPAPIRTFPLPTFYPSNPLSLFHLAVAWLRQVLLPPPAEPSVIHEGIWDPDTRSVHVKDPKSIRALWEQGFYGKGSLSRSEPNWFKRELSRRGLDGTTVSEERTASRREERRQVKWERAKAELEAIEKQKHEEAKLNSETVNAAIPEPPAAEIEPEPEVLLSSLPDHVLSATSTIPLSRAAPTNEFVPKTVAHGHVEPKPPVGPLELLALPNSYALVRGEELALSQPEPAPTEENVRKELKAPVGPIELLALPNSLVDLVALSVVSVLSEDAGVDEDESSTEDQLEASALTNDEPETSATEANDSTSSSSPPHTDGLPDSQPTQENVPATPERRKSVRFSSTVESTTFQHTDAASEVKNNNGSSDVEVFSSFVSAVEKPVILNVEPTVISQELVDKEHFQLAPEEAFFLTFGLGALRVVDPVTEAPISNEQLLIKLRANSYFPPRSVDNLSPEDPFLVQYAVYHHFRSLGWVPRHGIKFGVDWIIYQRGPVFDHSEFGIMVVPSFSDPRWSEFEHEESKKTWSWLMGVNRVLSHVLKSLVLVYVDVPPPPVFDEEMKKGGIAAALKKFTIREVMVRRFSVNRNR
What is the function of this protein?
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  This subunit may anchor the endonuclease complex to the nuclear membrane.  Probably carries the active site for 5'-splice site cleavage (By similarity).
What are the official names of this protein?
Probable tRNA-splicing endonuclease subunit tsp-2, tRNA-intron endonuclease sen2, tRNA-splicing protein 2.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family.
Protein: RN141_CANLF
Sequence: MGQQFSDQTQLVLNKLPEKVAKHVTLVRESGSLTYEEFLGRVAELNDMGTAKVASGQEKHLLFEVQPGSDSSAFWKVVVRVVCTKINKSTGIVEASRIMNLYQFIQLYKDITSQASGVLAQSSTSEDPDENSSSVTSCQASLWMGRVKQLTDEEECCICMDGRADLILPCAHSFCQKCIDKWSDRHRNCPICRLQMTGANESWVVSDAPTEDDMANYILNMADEAGQPHRP
What is the function of this protein?
May be involved in spermatogenesis.
What are the official names of this protein?
RING finger protein 141.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.