PharMolix/UniProtQA huggingface dataset:
Protein: AROA_BAUCH
Sequence: MQELLTLQPIVRVNGTIHLPGSKSISNRALLLAAQALGKTCLINLLDSYDVRYMLDALHKLGINYCLSIDRRSCEIDGIGRPLRVDTALELYLGNSGIALRSLVAALCLQNKNIIITGDKRMKNRPIGHLVDALRQGSAQIHYLEKDNYPPLLLQGGFYNGDITIDCSLSSQFLTSLLMMAPLASQDRCIFVKGRLVSKPYIDMTLAMMKSFGIVVQHDQYKIFYIKGKSQYRSPGHYLVEGDATNASYFLAAAAIRGGTVRVTGVGSNSIQGDIRFADILANMGAIIRWGVNYIECTRNSLCSIDIDMNALPDTAMTIAIVALFTYNGVTTLRNIYNWRIKETNRLVAMATELRKVGAIVVEGKEYLSIKPPNMFKIAKINTYDDHRIAMCFALVALSNVSITIVNPKCTYKTFPDFFKLLKGISIT
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_YERPE
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALETLTYTNKKAAGLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PURL_ZYMMO
Sequence: MTEENSSITAETVASHGLSPEEYDTIKQALGRTPNLVELGIFSAMWSEHCSYKSSRKHLRELPTTGSQVICGPGENAGVVDIGDGQAAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVANLNALRFGSPKHPKTPHLVSGVVAGIGGYGNCVGVPTVGGEVNFHPAYDGNNLVNAMTVGVAETNKIFYSAASGAGNPIVYVGSKTGRDGIHGATMASADFGKDAEEKRPTVQVGDPFSEKLLIEACLELMASDAIVAIQDMGAAGLTSSAVEMASKGEVGIELDMDMVPCREEGMTPYEMMLSESQERMLMVLKPGREAEAEAIFKKWELDFAIIGRVTDSKHMVLTWKGDIVCDIPLAPLADNAPCYDRPWVATPKAKALGAVPASGSITDNLVTLVGSPDLASRRWIWEQYDNMVGADTVQCPGGDAAVVRVHGTEKALAMSVDVTPRYCRADPEEGGKQAVAECYRNITAVGALPLASTDCLNFGNPERPEIMGQIVGAIKGIGEACRALDMPIVSGNVSLYNETRQDDGSSLAILPTPTIGGVGLLQDWRDSTTIAFKNTGEEIYLVGNSGQGHLGQSIWLREIAGREEGTAPSVDLAQEKATGDFIRAMIQDGMLCAVHDISDGGLAVALAEMALAGNIGATVEAHDKAIAEHAYYFGEDQGRYLVSSTNAVALVSAAEKAGIPVFRLGVTGGDAVVLNSQSVSLEKLRKSHEAFLPELMQ
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTPB4_HUMAN
Sequence: MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILTDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTVIKRQKQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLREQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEDDQKIFTDLQSEGFPVIETSTLTEEGVIKVKTEACDRLLAHRVETKMKGNKVNEVLNRLHLAIPTRRDDKERPPFIPEGVVARRKRMETEESRKKRERDLELEMGDDYILDLQKYWDLMNLSEKHDKIPEIWEGHNIADYIDPAIMKKLEELEKEEELRTAAGEYDSVSESEDEEMLEIRQLAKQIREKKKLKILESKEKNTQGPRMPRTAKKVQRTVLEKEMRSLGVDMDDKDDAHYAVQARRSRSITRKRKREDSAPPSSVARSGSCSRTPRDVSGLRDVKMVKKAKTMMKNAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit (PubMed:32669547).  Acts as TP53 repressor, preventing TP53 stabilization and cell cycle arrest (PubMed:20308539).
What are the official names of this protein?
GTP-binding protein 4, Chronic renal failure gene protein, GTP-binding protein NGB, Nucleolar GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SPG16_HUMAN
Sequence: MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDTEILERKTVLPSKHAVPEVIEDFLCNFLIKMGMTRTLDCFQSEWYELIQKGVTELRTVGNVPDVYTQIMLLENENKNLKKDLKHYKQAADKAREDLLKIQKERDFHRMHHKRIVQEKNKLINDLKGLKLHYASYEPTIRVLHEKHHTLLKEKMLTSLERDKVVGQISGLQETLKKLQRGHSYHGPQIKVDHSREKENAPEGPTQKGLREAREQNKCKTKMKGNTKDSEFPIDMQPNPNLNVSKESLSPAKFDYKLKNIFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS
What is the function of this protein?
Necessary for sperm flagellar function.  Plays a role in motile ciliogenesis.  May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia (By similarity).
What are the official names of this protein?
Sperm-associated antigen 16 protein, Pf20 protein homolog.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Note=Detected on the sperm flagellum axoneme. Detected in the central apparatus of the axoneme. Colocalizes with SPAG6 on microtubules (By similarity).
Protein: Y1806_DICDI
Sequence: MHTGEYSELLIGINGHMKKITLKLKNNLEEDQYSNCVKYGWIEKRCGKNQSFSSWKRMWFILKDSKLTYYIKEKNLKKRSSTIGSTQEFFKQQHGIDNNNCTNSNSNNNNNNSDLIHLSAPSLSSSTSSTISPISSSSSLTTTTTTTTTTTNANTNNGLSDSINHVYLEGELGKKKEGKGWKVRWMKLLEHSLVYYKSSKDKEPLGIVNLNECQDCEVNKESSNKFVVVHSSNRYYFKTNTKQELTQWVKSVKSRIPSINQTKMDLDQFQLKGVIEFNSIQQIAETFKFNSQPNCLTITTDEKAYYLSFDSNKDKLDWLNQLNLTINKFKGGFNSGGGSNNSSPSSLQSQQAKESGNGGSLSPNILGNFKSSIKPWRFSSSPSQGRVSIGGGGDRSSTQVKFVDNPLSKSSNKEEFDGGEYGSQILPRKSTIIGPNGGVKVSTSGAVELSPVLISSNNNNNNTISSSGNSIPTCLSDLINESSDNEDGDDLKMMIPESLKNEMMRRSAISSLKNFKLEIFIWSNHQEVFTFLFSDSVLVDQVKAFAFKKIPSLANLSVLDYRLGIDEDTLLEVEFLKFIYSHTMVELALKTCGIVKIGIFHHRKDRRVKEKLYSDKFYGHLLSQSPDGRKGNGVGIGGNGIPIEYSRSEPNLQSCLSSSPSTRETMVPSSPSSHQLITPPPSLKQYEQQLSSSSSSSSQQLQLQLQQQEQEQLLQEQPEAEQSQPEPQPQLEPESEIEIEELEQPIEELLNISTTPISIRSNSILSSSTSASSSPSSTPSLTPVIERQQKMSAAGWHSVNPSVTLNQRRQLISGCPGWNIEVSNPTSTFTSQGFKPKFDKQEHGFYRRYNFDGTSTVQSFLGVDMKMGPLAFSLAKDANDNYRGVLHTKHGAKTISEDSKNIVGILNLLSLSKKVKTKKVVSHLIGLLDPSIDAKLLNLASNQSELQKELLSFEERQTTSGFKFGMVYCRHGQVTDDEIFSNKQGSPEWDEFLSLIGDKIELVGWPHYSAGLDVKFNSTGTHSLYTDYHGNEVMFHVSTMLPFSTTDYQQIERKRQVGNDICVVIFNDGTLSYMPNTITSQFNHVIILVQYDKQNNGYKVSMACKDGVKSPFEPLSPNNLIKKSDIKDFILTKLINGELASLQAPVFASKITRTRESLLNYYISQFL
What are the official names of this protein?
PH and Rap-GAP domain-containing protein DDB_G0271806.
Protein: NUDT8_ARATH
Sequence: MDSVSLSEVTVIKGTTHLGFMHSFRQPFCGVKISPKFYLSKVDGPKAISSSSNTKSQFVYGGGSIAATSDSGYKMNGVNLKSRTLMSSAVKERSLLDAYDDEYGGVIVDHGKLPSNPYAFASMLRASLSDWRRKGKKGVWLKLPVEQSELVPIAIKEGFEYHHAEKGYVMLTYWIPEEEPSMLPANASHQVGVGGFVLNQHKEVLVVQEKYCAPSITGLWKLPTGFINESEEIFSGAVREVKEETGVDTEFSEVIAFRHAHNVAFEKSDLFFICMLRPLSDKIIIDALEIKAAKWMPLAEFVEQPMIRGDKMFKRVIEICEARLSHRYCGLSPHRLVSTFDGKPSSLYYNVVDDDHDPSHSNCSTEFYR
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity).  May be involved in plant immunity and act as a positive regulator of defense response through salicylic acid (SA) signaling (PubMed:25436909).
What are the official names of this protein?
Nudix hydrolase 8, AtNUDT8.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: SYM_MYCLE
Sequence: MRPYYITTAIAYPNAAPHIGHAYEYIATDAIARFKRLDGLDVRFLTGTDEHGLKVAQAAEAAGVPTAQLARRNSGVFQRMQEALHISFDRFIRTTDADHYKAAKEIWRRMDAAGDIYLGTYSGWYSVRDERFFVDSETKLLDNGIRVAVETGTLVTWTEKEQTYFFRLSAYVDKLLAHYDANPDFIGPEVRRNEVISFVSGGLEDFSISRTSFDWGVQVPEHPDHVMYVWIDALTNYLTGAGFPDTDSELFGRYWPANLHMIGKDIIRFHAVYWPAFLMSAGIELPRRIFAHGFLHNHGEKMSKSVGNIVDPMALVQTFGVDQVRYFLLREIPFGQDGNYSEEAIITRMNTDLANEFGNLAQRSLSMVAKNLGGVVPEPSEFTSADTALLTTADGLLERVRGNFDGQAMNLALEAIWLMLGEANKYFSSQQPWILRKSESEADQARFRTVLYTTCEVVRIAALLVQPVMPESAGKMLDLLGQEEDQRAFTAVSVRLAPGTVLPPPTGVFPRYQPSEIEGADPVKSSSKRREHNKRRE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PABP2_MOUSE
Sequence: MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGDPGGAGDYGNGLESEELEPGELLPEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEADPGDGAIEDPELEAIKARVREMEEEAEKLKELQNEVEKQMNMSPPPGNAGPVIMSLEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGISTTDRGFPRSRYRARTTNYNSSRSRFYSGFNSRPRGRIYRGRARATSWYSPY
What is the function of this protein?
Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product.  Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length.  Increases the affinity of poly(A) polymerase for RNA.  Is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA.  Cooperates with SKIP to synergistically activate E-box-mediated transcription through MYOD1 and may regulate the expression of muscle-specific genes.  Binds to poly(A) and to poly(G) with high affinity.  May protect the poly(A) tail from degradation.  Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation.  The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei.  Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein 2, PABP-2, Poly(A)-binding protein 2, Nuclear poly(A)-binding protein 1, Poly(A)-binding protein II, PABII, Polyadenylate-binding nuclear protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles between the nucleus and the cytoplasm but predominantly found in the nucleus. Its nuclear import may involve the nucleocytoplasmic transport receptor transportin and a RAN-GTP-sensitive import mechanism. It is exported to the cytoplasm by a carrier-mediated pathway that is independent of mRNA traffic. Nucleus; nuclear speckle (By similarity). Colocalizes with SKIP and poly(A) RNA in nuclear speckles (By similarity).
Protein: GWT1_CANAL
Sequence: MSSSLKQLKEQFVSDLTGGTIEEIYAVTSIALSSYLSFRLLKKSLGDLALIYDYILNVLTILASITVYSNSPSYLHYFIVIPSLVIYLVNYHVEKPSSPHRQNDTKEDKSDELLPRKQFITAYRSQMLIITNLAILAVDFPIFPRRFAKVETWGTSMMDLGVGSFVFSMGLANSRQLIKNHTDNYKFSWKSYLKTIKQNFIKSVPILVLGAIRFVSVKQLDYQEHETEYGIHWNFFFTLGFLPIVLGILDPVLNLVPRFIIGIGISIAYEVALNKTGLLKFILSSENRLESLITMNKEGIFSFIGYLCIFIIGQSFGSFVLTGYKTKNNLITISKIRISKKQHKKESSSFFSVATTQGLYLACIFYHLAFSLFISNLSFLQPISRRLANFPYVMWVVSYNATFLLCYDLIEKFIPGNLTSTVLDSINNNGLFIFLVSNLLTGFINMSINTLETSNKMAVIILIGYSLTWTLLALYLDKRKIYIKL
What is the function of this protein?
Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
What are the official names of this protein?
GPI-anchored wall transfer protein 1.
What is the protein family that this protein belongs to?
Belongs to the PIGW family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ACKA_RICAH
Sequence: MKDVILIANAGSSSLKISIFEIQNKQVKDKIYNIFLEKNDNKILCYINKKQESATDIKDDAIEMMIDLFEDWWKKQENLNLIATGHRIVHGGKNFNKPVIVNEKVSEDLRVLIPLNPLHQPYNLQVLDLFLQKYKEIVHIACFDTSFHFTNPPITKAFGLPKKYYAKGIIRYGFHGLSYKYVSSHFKEMTKEDLPIKTIIAHLGSGSSLCAIKNGLSLTSSMGFSVLDGVMMGTRTGNIDPGIVLYLIDHEKMTTKEITELLYKKSGLLGISGESSDIRTLLASNSPDAKFAIDLFVYRIVLEIGKLTAALEGIDGLIFTAGVGQNSAVIREMISAKLSWLGIKIDDTKNQKNEHLISTESSKVKVFAVPTNEELIIAEEVIKFL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HVR01_RAT
Sequence: MDLRLTYVFIVAILKGVLCEVKLEESGGGLVQPGMSVKLSCATSGFTFSDYWMEWVRQAPGKGLEWVAEIRNKANNYVAYYGKSLKGRFTLSRDDSKSIVYLQMNNIRSEDTGIYYCSRGYGGYSENWFVYWGQGTLVTVSS
What are the official names of this protein?
Ig heavy chain V region IR2.
Protein: IF1C_HEDHE
Sequence: MKEQKWIHEGLITESLPNGMFRIRLDNEDMILGYVSGKIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKNSKD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYP_STRP1
Sequence: MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPARTDLDRWVVLDKSIASMDDIPKEVLEDIKAELAAWMISGEDTIAYSTESSYAANLEMATNEYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVGNDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLTNAVAGANKDGFHMTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFKLGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRYAWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHD3_DROME
Sequence: MSSKRGADPDWKTPGKASKDKRPKTNAKKQKFRDEEYCKVCSDGGDLLCCDSCPSVYHRTCLSPPLKSIPKGDWICPRCIPLPGKAEKILSWRWALDRSVELRTSKGEKRREYFIKWHGMSYWHCEWIPEGQMLLHHASMVASFQRRSDMEEPSLEELDDQDGNLHERFYRYGIKPEWLLVQRVINHSEEPNGGTMYLVKWRELSYNDSSWERESDSIPGLNQAIALYKKLRSSNKGRQRDRPAPTIDLNKKYEDQPVFLKEAGLKLHPFQIEGVSWLRYSWGQGIPTILADEMGLGKTIQTVVFLYSLFKEGHCRGPFLISVPLSTLTNWERELELWAPELYCVTYVGGKTARAVIRKHEISFEEVTTKTMRENQTQYKFNVMLTSYEFISVDAAFLGCIDWAALVVDEAHRLRSNQSKFFRILSKYRIGYKLLLTGTPLQNNLEELFHLLNFLSSGKFNDLQTFQAEFTDVSKEEQVKRLHEILEPHMLRRLKADVLKSMPPKSEFIVRVELSSMQKKFYKHILTKNFKALNQKGGGRVCSLLNIMMDLRKCCNHPYLFPSAAEEATISPSGLYEMSSLTKASGKLDLLSKMLKQLKADNHRVLLFSQMTKMLNVLEHFLEGEGYQYDRIDGSIKGDLRQKAIDRFNDPVSEHFVFLLSTRAGGLGINLATADTVIIFDSDWNPHNDVQAFSRAHRMGQKKKVMIYRFVTHNSVEERIMQVAKHKMMLTHLVVRPGMGGMTTNFSKDELEDILRFGTEDLFKDGKSEAIHYDDKAVADLLDRTNRGIEEKESWANEYLSSFKVASYATKEDHEEHDDYNNDAENTDPFYWENLMGKSQPKLPKKQKKQSQQSQVDVESIMGKGKRIRKEIDYSNQYPSPNRATPSSIVLM
What is the function of this protein?
Helicase which acts in nucleosome-remodeling by catalyzing ATP-dependent nucleosome mobilization (PubMed:18250149).  Likely to be involved in the regulation of transcription (PubMed:18250149).
What are the official names of this protein?
Chromodomain-helicase-DNA-binding protein 3, ATP-dependent helicase Chd3.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=During embryogenesis, detected in nuclei before and after their migration to the membrane of the preblastoderm embryo (PubMed:18250149). Remains associated with condensed chromosomes in mitotic nuclei. Not detected in nuclei postgastrulation (PubMed:18250149). In polytene chromosomes of third instar larvae, weakly expressed at the chromocenter and fourth chromosome localizing mainly to the interbands (PubMed:18250149).
Protein: GCH1_ECOSE
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: DEOD_ACTSZ
Sequence: MTPHINAPAGAFADVVLMPGDPLRAKYIAETFLDQPELVTDVRNMLGYTGSYKGRRISVMGHGMGIPSCSIYSKELITEYGVKKIIRVGSCGAVRQDVHVRDVIIGLGACTDSKVNRIRFRDNDFAAIADFGMAQAAVQAAKNKKIKVHVGNLFSADLFYTPDVEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALSICTVSDHIRSGEQTSSEERQTTFNEMIEIALESVLLGDND
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: MYBS1_ORYSJ
Sequence: MTSQAATTTTTAAAAAAWTREDDKAFENALAACAAPPPADGGAPDDDWFAALAASVPGARSAEEVRRHYEALVEDVAAIDAGRVPLPRYAGEESAAPPDGAGAAAAASKDGGHRRDERKGGGGGYDGGKSCSKAEQERRKGIPWTEEEHRLFLLGLDKFGKGDWRSISRNFVISRTPTQVASHAQKYFIRLNSMNRDRRRSSIHDITSVTAGDQVAAQQGAPITGHQATGNPAAAALGPPGMKHHHHHHPGGAPPPMPMYSAAPMGHPVAGHMVPAAVGTPVVFPPGHAPYVVPVGYPAPPAKMHQ
What is the function of this protein?
Transcription activator that binds to 5'-TATCCA-3' elements in gene promoters.  Derepresses strongly the sugar-repressed transcription of promoters containing SRS or 5'-TATCCA-3' elements.  Functions with GAMYB to integrate diverse nutrient starvation and gibberellin (GA) signaling pathways during germination of grains.  Sugar, nitrogen and phosphate starvation signals converge and interconnect with GA to promote the co-nuclear import of MYBS1 and GAMYB, resulting in the expression of a large set of GA-inducible hydrolases, transporters, and regulators that are essential for mobilization of nutrient reserves in the endosperm to support seedling growth (PubMed:22773748).
What are the official names of this protein?
Transcription factor MYBS1, Myb-related protein S1, OsMYBS1, Syringolide-induced protein 1-3-1B.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Preferentially localized to the nucleus under sugar starvation conditions. Glucose inhibits nuclear localization.
Protein: CYSH_BACCR
Sequence: MLTYETWEENVVSFSEEDETKGALSVLNWAYKEYKDEVVYACSFGVEGMVLLHIINQVNPSAKVVFLDTNVHFQETYELIRKVRERFPSLNIIEKQPELTLDEQAKLHGEKLWESNPNLCCKIRKILPLEKSLVVEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGDGGDSRDGRWAGKVKTECGLHYQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC174_RAT
Sequence: MDRKKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTSNKKPSIWSKQNAGVSSRAEKDAEQKLEEQKTLDKSREKLEEKAKLYEKMTKGDFLDEEVEDMYLVDFTQKIIDKRKEMEVLGATRDSRIKEERDAAVAAANDDDDEEEFSEKDIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPSLLEMDKNLQGRLFVSPANEKTLLSEDMRKELQRQQWEEEEREALKKPMGPIHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRIKRENIKEKRKAILEARLAKLRQKKMKKSKVDGTEEESRADGVVTEPSEPKSVPAPPPVAQSSKVEVIIQERKDSKPGVPHIREWDRGKDFSFGFWSKKQSELRAERDPEFAPPSNYFVGQKRTGSLSSQPWSRPGAAPSDLGHSSGQSQEPSSSHTSTPASESSPQAPTVTFQTLDDMISYYKQVT
What is the function of this protein?
Probably involved in neuronal development.
What are the official names of this protein?
Coiled-coil domain-containing protein 174.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDM5C_PIG
Sequence: MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEESGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYSNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARERRFPNSELLQRLKNCLSEAEACVSRALGLVSGQEAGPHRVAGLQMTLAELRAFLDQMNNLPCAMHQIGDVKGILEQVEAYQAEAREALASLPSSPGLLQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVAPSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIHEAENIPVHLPNIQALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASPNTSSSATSICVCGQVPAGVGALQCDLCQDWFHGRCVSVPRLLSSPRPSPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAISWQGRARQALAFEDVTALLGRLAELRQRLQAEPRPEEPPTYPSTPAFDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPGEGSDLELLSSLLPQLTGPVLELPEATRAPLEELMLEGDLLEVTLDENHSIWQLLQAGKPPDLARIRTLLELEKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSWPEAEEAHEEEELEEETGGEGPPQPLPATGSPSTQENQNGLEPALGASSGSSVPFSTLTPRLHMSCPQQPPQQQL
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'.  Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'.  Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 5C, Histone demethylase JARID1C, Jumonji/ARID domain-containing protein 1C, Protein SmcX, [histone H3]-trimethyl-L-lysine(4) demethylase 5C.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.