PharMolix/UniProtQA huggingface dataset:
Protein: PSBB_ILLOL
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVSGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTITNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQSVNPAWGAEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVGTGLAENLSLSEAWSKIPDKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPIFRDKDGHELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYGDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTRRQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYI_BRUA2
Sequence: MTDTTKIDYSKTLYLPQTEFPMRAGLPQREPLFVQRWEEMNLYKKLREQAKDRPLYVLHDGPPYANGNIHIGHALNKILKDVITRSFQMRGYNSNYVPGWDCHGLPIEWKIEEKYRAAGKNKDEVPINEFRKECREFASNWIKVQTEEFKRLAILGDFENPYTTMNFHAEARIAGELLKFAASGQLYRGSKPVMWSVVERTALAEAEVEYHDIESDMIWVKFPVAGEVATENDLSGSAVVIWTTTPWTIPGNRAVSYSSRIEYGLFEITEAENDFGPRPGERLVFADKLVEECCAKAKLQFKRLRSVSAEELGKIVLDHPLKGFGGGYEFVVPMLDGDHVTDDAGTGFVHTAPSHGREDFEAWMDNARQLEARGIDPNIPFPVGDDGFYTKDAPGFGPDREGGPARVIDDNGKKGDANKVVIEQLIAADKLFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKNLGDGTTLRSRALKAIDETRFVPAAGQTRLRSMIEGRPDWVLSRQRAWGVPICVFVDEEGNILQDDAVNKRIMDAFEKEGADAWFADGARERFLGARAGEGWTQVRDILDVWFDSGSTHTFTLEDRPDLKWPADVYLEGSDQHRGWFHSSLLESCGTRGRAPYNAVVTHGFTMDEHGKKMSKSLGNTVTPQDVIKESGADILRLWVMTTDYWEDQRLGKSIIQTNIDAYRKLRNTIRWMLGTLAHDEGENVAYADLPELERLMLHRLTELDELVRSGYDTFDFKRIARALVDFMNVELSAFYFDIRKDALYCDAPSSIRRKAALQTVREIFVRLTTWLAPMLPFTMEEAWLDRYPQSVSIHAEQFRPTPAEWRDDVLAEKWRKVRAVRRVVTGALELERADKRIGSSLEAAPVVYIADKSLSDSLEGLDFAEICITSGISVSDAAAPEGAFTLGDVKGVAVVPERAKGEKCARSWRYTTDVGADPEFPEVSARDAAALRELQALGKL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGN2_HUMAN
Sequence: MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSPASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI
What is the function of this protein?
Transcriptional regulator.  Involved in neuronal differentiation.  Activates transcription by binding to the E box (5'-CANNTG-3').
What are the official names of this protein?
Neurogenin-2, NGN-2, Class A basic helix-loop-helix protein 8, bHLHa8, Protein atonal homolog 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB5_PHATC
Sequence: MSAEKEYILDEISQHTTTESCWLIIGNASNGGPKVYDVTKYLDDHPGGAEVMLDVAGQDADEFFEDIGHSKEARAELKNYLVGNFKIDAATLAKMKADAEAKAQQKNSGTGIMLIVLMALFAIAYGYYQTQMK
What is the function of this protein?
Hemoprotein that functions as an electron carrier for membrane bound monooxygenases involved in sterol biosynthesis.
What are the official names of this protein?
Cytochrome b5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: GOGA5_DROME
Sequence: MSSWITGLADKAENILNKLDQNAATALQTENATGSADPMRRSMTSSTQSLSTSLKSTLSPVRRSGANSSSSVKSDGGVSVVTKDMRQKMTTSASFSNSPDISANSMDTNELAAFKIALNEITAERDELRLRLEDLNNETEKFDLHQHTQVLEALVKSLSEERDKAVHDYNEAQAANMAYVHSISELETNLAKLQQEYISAAHKLQMQTKETEQQRQELQEYRIKAQRALQAKDSLIAELKAKPTEEGADPNLVSKDSETRFLQIEHESLKQELEHANEELQKARLQLDDYVSQERQRQVELSSARQREETLAKELRQAREHSVTSESDQRVLTQELASLRQQLSNQMAAAATRLQEREQQLQQMRQRLSEEANTGAKSDYETRLKALTQSLVERQSLLERVTSERNALRLQHEKAQTQLQQNMHLVEMESQRGSSRHTMLNSTDDVKAQFPLLMHPSPFDNRVARRFKRALRQADSMGIRVGTFLRRYPMMRVSVIVYVALLHLWVMFVLLSTTPN
What is the function of this protein?
May be involved in maintaining Golgi structure and in intra-Golgi transport.
What are the official names of this protein?
Golgin-84.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein.
Protein: YQGF_XYLF2
Sequence: MPEASSPFPDGIVLGFDVGTRRIGVAVGSALGAGARAVAVIDVHGVAVDWNALDRVKRNWLPVGLVVGDPLTLEGHDQPIRKQAHAFACQLRERYRLPVVLVDERSSSVEAASRFAGARAAGYKRRRDADTLDAIAAAVILERWLADPMQATSLP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_SHEPA
Sequence: MKFSPLVDELIQSLRCLPGVGPKSAQRMAFQLLERDRKAGAKLADSLAKAMSEVGHCQSCRTFTEETYCPICVSTKRGHSEVICVVETPADVLAIEAGGHFSGRYFVLLGHLSPLDGVGPDELGLDLLEQHLATGDVSELILATNPTVEGDATAHYIADMAKRHQLTVSRIAHGVPVGGELEYVDSTTLALSFNGRLPM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MOAA_CORGB
Sequence: MTTRLYLSPTPPRNDREGASKSTSASIKHDAYLPPADGNRVLVDRFGRIARDLRVSLTDRCNLRCTYCMPAEGLEWLPTEQTLNDAEVLRLLHIAVVKLGIRQIRFTGGEPLLRKNLEDIIAGTAALRTDEGEKVHIALTTNGLGLDKRIAGLKEAGLDRVNISLDTIDAERYVSLTRRDRLSGVLASIDAAVAAGLHPVKINAVVMPGVNEVDIVPLAEYCISKGAQLRFIEQMPLGPREQWKRGDMVTAEEILARLEEKFTLSPAKEPRGAAPAALWNAVDKSNPVITGQIGIIASVTHPFCGDCDRSRLTTDGTIRNCLFSRTETPLRDALRDGASDDELAQLWAGAMWEKKPGHGIDDEGFLQPDRPMSAIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: Y1488_MYCTO
Sequence: MQGAVAGLVFLAVLVIFAIIVVAKSVALIPQAEAAVIERLGRYSRTVSGQLTLLVPFIDRVRARVDLRERVVSFPPQPVITEDNLTLNIDTVVYFQVTVPQAAVYEISNYIVGVEQLTTTTLRNVVGGMTLEQTLTSRDQINAQLRGVLDEATGRWGLRVARVELRSIDPPPSIQASMEKQMKADREKRAMILTAEGTREAAIKQAEGQKQAQILAAEGAKQAAILAAEADRQSRMLRAQGERAAAYLQAQGQAKAIEKTFAAIKAGRPTPEMLAYQYLQTLPEMARGDANKVWVVPSDFNAALQGFTRLLGKPGEDGVFRFEPSPVEDQPKHAADGDDAEVAGWFSTDTDPSIARAVATAEAIARKPVEGSLGTPPRLTQ
What are the official names of this protein?
Uncharacterized protein MT1533.2.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CAH2_HUMAN
Sequence: MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide (PubMed:1909891, PubMed:1910042, PubMed:1336460, PubMed:8485129, PubMed:8399159, PubMed:8218160, PubMed:8262987, PubMed:8451242, PubMed:7901850, PubMed:7761440, PubMed:8639494, PubMed:9265618, PubMed:17330962, PubMed:9398308, PubMed:11327835, PubMed:12056894, PubMed:17346964, PubMed:12171926, PubMed:15453828, PubMed:16214338, PubMed:15865431, PubMed:16106378, PubMed:15300855, PubMed:15667203, PubMed:18942852, PubMed:11831900, PubMed:17251017).  Can also hydrate cyanamide to urea (PubMed:10550681, PubMed:11015219).  Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (PubMed:15990874).  Essential for bone resorption and osteoclast differentiation (PubMed:15300855).  Involved in the regulation of fluid secretion into the anterior chamber of the eye.  Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption.
What are the official names of this protein?
Carbonic anhydrase 2, Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II, Cyanamide hydratase CA2.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
Protein: RUVB_SHEB2
Sequence: MIEADRLIQPQIQAQDESIDRAMRPKMLDEYTGQDDTRAQLKVFIQAAKNRNEALDHMLIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLESGDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIPLRLEFYNIKDLSTIVTRSAQVMELDIDAEGAFEIARRSRGTPRIANRLLRRVRDYAQVKHDGAVTKFVAEHALDLLDVDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRIATARAYQHFELIKPE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TAM_PSEAE
Sequence: MVHDLLRDRADLEARWNPSAYMQFARLRQRPVVELLDHIEPCCPERIYDLGCGTGIATELLARRWPLAELYGVDSSVEMLEEAARLPIKASWERANLRHWCAERPASLLFAAAVLHFLEDHGKLLPRLLGQLTPGGCLAAHMPNWRDASWYRLMLDALDSAGPGGASLGSPALRYRLHRRNVLSLDNYYRLLAPLTAELDIWETEYLQVVDGNDPIFDWIKVSALRPVLGELDEEARRRFLDRYLELLHRHYPRELDGRTLFPFRRVFIVASLGR
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPDB_MYCTU
Sequence: MSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRVFETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMFGVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKVDPDNPAFRFVNVYRVVSNLGVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDPKSLRDREIRS
What is the function of this protein?
Involved in the final steps of cholesterol and steroid degradation (PubMed:28377529).  Opens the last steroid ring of cholesterol by catalyzing the hydrolysis of (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA (COCHEA-CoA) to 6-methyl-3,7-dioxodecanedioyl-CoA (MeDODA-CoA) (PubMed:29581275).
What are the official names of this protein?
Cholesterol ring-cleaving hydrolase IpdB subunit, (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase beta subunit, COCHEA-CoA hydrolase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
Protein: RL17_BUCA5
Sequence: MRHRKSGRQLNRSSTHLNSMLKNMACSLFTHEVIKTTLSKAKELRRIVEPIITLSKIDTVSHRRLVFSRIRDNAIVAKLFKKLGPCFFSRLGGYTRILKCGFRSGDKAPMAYIELVDRVKNNKKNEILKK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SECA2_MYCVP
Sequence: MLADVLRLGEARTVKQLSAIADHVDSLARGVENLTDAELSSRTDVFRRRVADGDVLDELLPEGFAVAREAAWRVLGLRPYHVQVMGGAALHFGNIAEMMTGEGKTLACVMPAYLNAIGGKGVHIVTVNDYLAGRDAEQMGRVHRFLGLTVGVILSEMKPDERRAAYAADITYGTNNEFGFDYLRDNMAGRLEDRVQRGHCYAIVDEVDSILIDEARTPMIISGPADDATRWYAEFARLAALMTRDVHYEVDTRRRTIGVSEAGVALVEDQLGVDNLYQVVHAPLVGHLNNAVRAKELFHRDREYIVNDDGEVLIVDEFTGRVLVGRRYNEGLHQAIEAKEGVEVKPENQTLATITLQNYFRLYDRLAGMTGTARSEASEFRDIYRLGVITIPPNRPVVRRDEVDVVYKTESAKFDAVVEDVVGRHAAGQPVLIGTTSVEKSEYLSGRLTERRVPHTVLNAKHLEQEAAIVAEGGRRGAVTVATDMAGRGTDIMLGGNVDFLTDKRLRSRGLHPTRSPEEYDAAWAEVRREVAAESRTEAREVVALGGLYVLGTERHESRRIDNQLRGRSGRQGDPGETRFYVSLCDELMRRSATFDLEKLMSRLKMPEREPIEAKVVSRAIRNAQSQVEQANFDMRRSVVKYGQVLDQQRRIVYQARSRLLEGEDMQHQIFHMIGDVVTAYVNECTAGRRTADWDLETLRAALSTLYPVVWQPDPRPHMRGLTRSVLRHEVIADARRALVRRKAAIEARSGLRVMRELERAILLDCLDSKWRAHLYEMDYLAAGIGMRALAGADPVVEYHREGHRMFVRMLEAVKEQSIRSLFDATTRMLAPIMPSAARSPGTPDPRWPF
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PSA2B_ARATH
Sequence: MGDSQYSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKASNGVVIATEKKLPSILVDEASVQKIQHLTPNIGTVYSGMGPDFRVLVRKSRKQAEQYLRLYKEPIPVTQLVRETATVMQEFTQSGGVRPFGVSLLVAGYDDKGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELDDAIHTAILTLKEGFEGEISSKNIEIGKIGTDKVFRVLTPAEIDDYLAEVE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-2-B, 20S proteasome alpha subunit B-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HTPX_TRIV2
Sequence: MGNQFKTLALLAALSGLLIAISYWVIGGSSGLIIGIGLAAVTNLLSWYQSDKIALAVYRAQPVSESQAPRLYRMVQRLSQRANIPMPGVYIVPGQTANAFATGRDPEHAAVAVTEGILNILPEDELEAVIAHELTHIINRDTLTQAVAATVAGAISFLAQMVSYSLWFGGIGGRDNERGGNPLGVLLTVVLAPIAATIIQLAISRTREFSADAGSARLTGNPRALARALQRLEAAARQIPLNANPAFEPLLIINSISGQFLGNLFSSHPSTEARVQALLKLEKQLPTIA
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURC_RHOPB
Sequence: MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASEGANVSRLRDKGIAIHVGHQAENVAGADVVVVSTAIKRDNPELLAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGEFDPTVINGGIINAYGTNARLGAGEWMVVEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFDAVQEAFRDFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGENPQADVRLLDLTPNGGSSAFRVAFRDRKAGTAHEIADLVLPMPGRHNALNATAAIAVAHELGLSDDTIRKALAGFGGVRRRFTKTGEWNGVTIIDDYGHHPVEIAAVLKAARESTKGKVIAVVQPHRFTRLQSLFEEFCTCFNDADVVVVAEVYPAGEAPIEGVDRDHFVLGLRAHGHREVIPLQESAALASVVYGAAHSGDYVVCLGAGNITQWAYALPGELKALD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_HALWD
Sequence: MTDSGEIDPQTAEEKVTDAQTAALSLSNLSTARRNEALTAIADTIERNVDRILEANAADVADAEKQVDAGEYTQAFVDRLTLSTSKIESIAEMVRSVAEQDDPLGETLTARELDDDLNLYKVTVPIGVIGTVFESRPDALVQISALSLKSGNAVILKGGSEAERSNRVLYNCILEATPEVPSGWAQLIEAREDVQTLLEMDDAVDLIMPRGSSSFVQYVQDNTSIPVLGHTEGVCHVYVDSEADLEMATAVAYDAKVQYPAVCNAVETLLVHESVAPSFLSQMMKQYRDAGVEIRGDERTQSIVDTESNISEEIIAATEADWTTEYGDRIVSIAVVDSLTDAIDHINMYGSKHTESILTQDDNRAEQFMRAVDAASVFHNASTRFADGFRFGLGAEVGISTGKIHARGPVGLDGLTTYKYHLEGDGQQVATYAGSDAKPFDHAEFDETWPVRNDDG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_BACCZ
Sequence: MMTYEYILVRYGEMTTKGKNRSKFVSTLKDNVKFKLKKFPNIKIDATHDRMYIQLNGEDHEAVSERLKDVFGIHKFNLAMKVPSELEDIKKGALAAFLQVKGDVKTFKITVHRSYKHFPMRTMELLPEIGGHILENTEDITVDVHNPDVNVRVEIRSGYSYIMCDERMGAGGLPVGVGGKVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPPFTSERAKQKVIDLAQELTKYCKRVTLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMRITERIAEERNALAITTGESLGQVASQTLDSMHTINEVTNYPVIRPLITMDKLEIIKIAEEIGTYEISIRPYEDCCTVFTPASPATKPKREKANRFEAKYDFTPLIDEAVANKETMVLQTVEVVAEEEKFEELF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_FERNB
Sequence: MVSEKIKQEVEKLRKEIEYHNYRYYVLAQPVISDEEYDKLMKRLMELEEKYPELKTPDSPTQRVGGQLIEGFETVEHSEPMLSLDNTYNENEIRNFHERIRKVVRDVQYVAELKIDGVSIALRYENGLLVRAITRGDGLRGDDVTANVKTVKSIPLRLPEPLTIEVRGEIFMPVQYFEEFNRQREEEGLLPFANPRNATAGTLHLLDPSQVAQRKLDSFMYYIVKPQQYDLKTQWDALKFLEKLHFKVNPHSKLLSSIEEVIDYWKEWTEKRKKLEYWIDGVVVKVNDFEQQNELGWTAKSPRWAIAFKFPAQQVRTKVLNITFQVGRTGTITPVAEFEPVELEGSIVKRASLHNFDYIKENDIRVGDYVFIEKAGGIIPQISYVLKELRDGDEIETVPPEKCPECGGPVGKESGEYVAYKCLNPHCPAKLKRHIEVFVSRQAMDIQGLGPKIISKIVDAGLVKDIADLYYLNIFDLAQISGLGPKMISNILSEIEKSKQNPIEKLLVGLGIPGVGEKIAKVLAKKYKSMEELSKADIKELSEIEGIGEDIAKNIVEYFNSPKTKEILEKLRKAGVNLESAETTTSNILDGLTFCVTGTLENFSREEIKRFIESLGGHFTDNLTKKTDYLLVGTNPGSKLEKAKKFGVKVLNEQEFLEMLEKKGVELKESWKKPKPKDTLF
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SPN1_SCHPO
Sequence: MASMVLADGMPTVKDDSTRSRGSDVDSFTSTDNVTQINVEAAISENKNEEKPIQDNSEQEFNPHVSIIQRQLNGYVGFASLPNQWHRRCVRQGFNFNVLVLGESGSGKSTLVNTLLNRDVYPPTQKSLTGDFGVNPEPTVMINSSAVEIVENGISLQLNVIDTPGFGDFIDNTDCWQPVLTDIEGRYDQYLELEKHNPRSTIQDPRVHACIFFIQPTGHAISAMELRVMLALHEKVNIIPIIAKADTLTDDELNFTKEMILRDIQYHNIRIFFPPTYETDDPESVAENADIMSRIPFAIIASNTFVVNNEGKRVRGRRYPWGVVEVDNEEHSDFPKLREMLIRTHLEELKEQTNKLYEAYRTERLLSSGISQDHSVFREVNPSAKLEEERALHEEKLMKMEAEMKTIFSQKVQEKEDRLKQSENELRTRHREMKAALEKQKADLIDHKNRLMQAKAAAENEKSKRKFFK
What is the function of this protein?
Plays a role in the cell cycle.  Involved in a late stage of septum formation leading to the separation of the daughter cells.
What are the official names of this protein?
Septin homolog spn1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes to the medial ring at the cell cortex of dividing cells.
Protein: FBL72_ARATH
Sequence: MDHVSSLPDEVLYHILSFLTTKEAALTSILSKRWRNLFTFVPNLDIDDSVFLHPQEGKEDRYEIQKSFMKFVDRVLALQGNSPIKKLSLKLRTGFDSHRVDGWISNALARGVTELDLLIILNLVTLKLNSVRVDWLAAGDIFLPMLKTLVLHSVRLCVDNVNWGGKDVNVSNASLKILTVNYNICLGTFSVDTPSLVYFCFTEYVAIDYPVVIMQNLFEARISLLVTQDQIERARAPNIDWVEDDVVLRLVNMEKLIKGIRNVQYMYLSPNTLEVLSLCCESMPVFNNLKSLTLKSHKSRGWQAMPVLLRNCPHLETLVLEGILHHVTDKCGYACDCVSREEKGCSLTSCPVKVLEIKGFRGTIKEMHMIKHFVNYFPCLMETNIYIEESGPPKLRVPQVCEFIAEMMEHYGKSSSFNVQLLVGGYLYKKWTAQ
What are the official names of this protein?
Putative F-box/LRR-repeat protein At4g13960.
Protein: PLSY_PROMA
Sequence: MDFSISTIALFTLLVSYLLGSLPSGYLAGKWILGIDLREIGSGSTGATNVLRHVGKTPALFVFFIDVTKGIGAILIAKSFLLDESLQIAAGLASLSGHIWPVWLKGKGGKAVATGLGVFLGISWQVGLGSLGIFLLILSIWRIVSLASISAAISLPVLMLINSKETFSIPYIVISFIAMILVLWRHRSNLIRLIKGQEPRIGKSN
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAB_BRUA2
Sequence: MSDDTTQIEPAMAQETSPRANTRKVFVKTYGCQMNVYDSQRMADSLAAEGYVATDTPDDADLVLLNTCHIREKASEKLYSALGRLRKMRDARAADGKELTIGVAGCVAQAEGQEILRRAPNVDLVIGPQTYHRLPNALARVRGGEKVVETDYAIEDKFEHLPAPRREETRKRGVSAFLTVQEGCDKFCTFCVVPYTRGSEVSRSVKQIVAEAERLADSGVRELTLLGQNVNAWHGEGEDGREWGLGELLFRLARIPGIARLRYTTSHPRDMDDSLIAAHRDLRQLMPYLHLPVQSGSDRILKAMNRRHKADEYLRLIERIRNVRPDMALSGDFIVGFPGETDQDFEDTMQLVRDVNYAQAYSFKYSPRPGTPGADLDDHVEEAVKDERLQRLQALLSAQQYAFQDSMIGRKMDVLLEKPGREAGQMVGRSPWLLPVIIDDNKDRVGDIIHVKIVSTGTNSLIAQKLA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.