PharMolix/UniProtQA huggingface dataset:
Protein: FLPA_SULAC
Sequence: MSEIEKVTKTQFDNVYECIFNDGTTRLCTKNLSPGHNVYGERLIKYGGVEYREWNAFRSKLAGAIVKGLKYNPIVKGSKILYLGAASGTTPSHISDIVELQGKVYSVEFSPRVIRELLLVAQYRPNMFPILADARFPQYYKSLVENVDIVYVDIAQPNETEIAMYNARFFLKKNGYMMIAIKSRSIDVTKDPREIYNAEAKKLEDAGFDIREVLELDPYDKDHAMIVVKYK
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: ISPF_CLOBL
Sequence: MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: HSLV_RHIWR
Sequence: MSELPKWHGTTILSVRKGGKVVVIGDGQVSMGNTVMKPNARKVRKLGDGSVIGGFAGATADAFTLFDRLERKLEQHGGQLLRAAVELAKDWRTDKYLRNLEAMMIVADREVTLILTGNGDVLEPVGGVAAIGSGGNFALSAARALVDYEADAETICRKAMAIAADLCVFTNDSLTIETLDSAA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGA1_YEAST
Sequence: MTLSFAHFTYLFTILLGLTNIALASDPETILVTITKTNDANGVVTTTVSPALVSTSTIVQAGTTTLYTTWCPLTVSTSSAAEISPSISYATTLSRFSTLTLSTEVCSHEACPSSSTLPTTTLSVTSKFTSYICPTCHTTAISSLSEVGTTTVVSSSAIEPSSASIISPVTSTLSSTTSSNPTTTSLSSTSTSPSSTSTSPSSTSTSSSSTSTSSSSTSTSSSSTSTSPSSTSTSSSLTSTSSSSTSTSQSSTSTSSSSTSTSPSSTSTSSSSTSTSPSSKSTSASSTSTSSYSTSTSPSLTSSSPTLASTSPSSTSISSTFTDSTSSLGSSIASSSTSVSLYSPSTPVYSVPSTSSNVATPSMTSSTVETTVSSQSSSEYITKSSISTTIPSFSMSTYFTTVSGVTTMYTTWCPYSSESETSTLTSMHETVTTDATVCTHESCMPSQTTSLITSSIKMSTKNVATSVSTSTVESSYACSTCAETSHSYSSVQTASSSSVTQQTTSTKSWVSSMTTSDEDFNKHATGKYHVTSSGTSTISTSVSEATSTSSIDSESQEQSSHLLSTSVLSSSSLSATLSSDSTILLFSSVSSLSVEQSPVTTLQISSTSEILQPTSSTAIATISASTSSLSATSISTPSTSVESTIESSSLTPTVSSIFLSSSSAPSSLQTSVTTTEVSTTSISIQYQTSSMVTISQYMGSGSQTRLPLGKLVFAIMAVACNVIFS
What is the function of this protein?
Cell wall anchoring subunit of the a-agglutinin heterodimer.  S. cerevisiae a and alpha cells express the complementary cell surface glycoproteins a-agglutinin and alpha-agglutinin, respectively, which interact with one another to promote cellular aggregation during mating.
What are the official names of this protein?
A-agglutinin anchorage subunit, A-agglutinin cell wall attachment subunit.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Protein: PAX2A_XENLA
Sequence: MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTPVGTPGHTLVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDGSDGSGPNGDSQSSVESLRKHLRADNFTQQQLEALDRVFERPSYPDVFQTAEHIKSEQASEYSLPALTPGLDEVKSSLSASGNADLGSNVSGPQSYPVVTESFASHLYVKQEPHEASLTPFTPSSLASSGLADIQPFQMALTVDASTPTYSSFTHHGPHYGQFGSQPLIAGRDMSSTTLPGYPPHVPPTGQGSYPTSTLAGMVPGTNVSVHHSVQPVECCSCLSSSKPCLFHCRTGSGSEFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSATSRGSAPPTAATAYDRH
What is the function of this protein?
Probable transcription factor.  Involved in kidney development, acting synergistically with lhx1/lim-1 in pronephric morphogenesis during the tailbud stages (By similarity).
What are the official names of this protein?
Paired box protein Pax-2-A, xPax-2a.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS1_MYCS2
Sequence: MPSPSVTSPQVAVNDIGSAEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPSRELSIKHDVDPNEVVSVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEELKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRDLQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNQLQKGAIRKGVVSSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGLVHISELSERHVEVPDQVVQVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPSKYGMADSYDEQGNYIFPEGFDPETNEWLEGFDKQREEWEARYAEAERRHKMHTAQMEKFAAAEAEAANAPVSNGSSRSEESSGGTLASDAQLAALREKLAGNA
What is the function of this protein?
Binds mRNA, facilitating recognition of most mRNAs by the 30S ribosomal subunit during translation initiation (By similarity).  Plays a role in trans-translation; binds tmRNA (the product of the ssrA gene) (PubMed:25430994).  Binds very poorly to pyrazinoic acid (POA), the active form of the prodrug pyrazinamide (PZA); POA does not disrupt trans-translation in this organism (PubMed:21835980).  M. smegmatis is resistant to the antibiotic PZA (PubMed:25430994).  In trans-translation Ala-aminoacylated transfer-messenger RNA (tmRNA, product of the ssrA gene; the 2 termini fold to resemble tRNA(Ala) while it encodes a short internal open reading frame (the tag peptide)) acts like a tRNA, entering the A-site of the ribosome and displacing the stalled mRNA (which is subsequently degraded).  The ribosome then switches to translate the ORF on the tmRNA, the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and thus targeted for degradation.
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: RPOC1_CRYJA
Sequence: MSDQDKHEQLRIGLVSPEQILAWSERILPNGERVGQVTTERTLDYRTYEPVRDGLFCERIFGPKKRGVCACVKPRMMENDKENYNSNFCTQCGVELAIDPRIRRYRMGYIKLACPVVHIWYFKRRPSYIADLLDKTRKELEDPVYCDVCITRPTAKKPTLLRFQGLRPSKYESWAEKIAYYLSWDFGLVQEREIATGGKAIREQLAGLDLQMIIDRSYIEWKEIDEVISILFSEPENLFSNRKIYAQFKEQKLQKLRRRKDLLVRRMRFAKYFLRTNVEPQWMVLCLLPVLPPDLRPMFQLNEGGVITSDLNELYQTVIRRNNNVLQFIETTSAFLIPDLLPDQKKLVQQAVDALLDNSIGTQPVRDSHDRPYKSFSDFIQGKEGRFRENLLGKRVDYSGRSVIVVGPLLSLYQCGLPREIAIELFQAFLIRDLVERQIAPNLRAAKFLIRDRGPIIWNVLKQIMQKHPILLNRAPTLHRLGIQAFIPVLINERAIRLHPLVCAGFNADFDGDQMAVHVPLSMEAQVEARLLMFSHLNLISPTIGDPICVPTQDMLLGLYRSTLQKNQGIYENRYHPNSSKKKIVSPSFYSYDDALKAYEQKQIDLDSPLWLRWGREIDTSIINSVNRELPIEVQYECLGTFYEIYDHFRIRKGRVGEILNKYIRTTVGRIRFNREIEEAIKGLWTYDIRQEMLLFRI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ERYK_SACEN
Sequence: MTTIDEVPGMADETALLDWLGTMREKQPVWQDRYGVWHVFRHADVQTVLRDTATFSSDPTRVIEGASPTPGMIHEIDPPEHRALRKVVSSAFTPRTISDLEPRIRDVTRSLLADAGESFDLVDVLAFPLPVTIVAELLGLPPMDHEQFGDWSGALVDIQMDDPTDPALAERIADVLNPLTAYLKARCAERRADPGDDLISRLVLAEVDGRALDDEEAANFSTALLLAGHITTTVLLGNIVRTLDEHPAHWDAAAEDPGRIPAIVEEVLRYRPPFPQMQRTTTKATEVAGVPIPADVMVNTWVLSANRDSDAHDDPDRFDPSRKSGGAAQLSFGHGVHFCLGAPLARLENRVALEEIIARFGRLTVDRDDERLRHFEQIVLGTRHLPVLAGSSPRQSA
What is the function of this protein?
Responsible for the C-12 hydroxylation of the macrolactone ring of erythromycin.  Thus, EryK catalyzes the hydroxylation of erythromycin D (ErD) at the C-12 position to produce erythromycin C (ErC).  Erythromycin B (ErB) is not a substrate for this enzyme.
What are the official names of this protein?
Erythromycin C-12 hydroxylase, Cytochrome P450 113A1, CYP113A1, Erythromycin D C-12 hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: CTAA_BACHK
Sequence: MQRFIKWLAVITSLDLLIVLLGGALVTKTGSGQGCGKSWPLCNGEFVPSNLSMETIIELSHRLTSGSAGILVTLLCILSWKYYKHVRETKTLAILSFVFLVAQALMGAAAVVWGQMPAVLAIHFGISLISFASVILLTCLIFEIDQKFDARSLIMDKKMKFHIYGVTIYCYLVVYTGALVRHERASLACPDFPLCSKNRPMPTQLHEWVQMGHRLAAMLIFVWILYAMILAIRHYKQQPVVYWGWIISFILVTLQAIVGILVVFTNASLAMALLHSLFISCLFAVLCYLVMLGTRSKVNAKEAASTSKQTK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RK14_TOBAC
Sequence: MIQPQTHLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAVPNMPLERSEVVRAVIVRTCKELKRDNGMIIRYDDNAAVVIDQEGNPKGTRIFGAIARELRELNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y3771_PSEFS
Sequence: MDTKLLDILACPICKGPLKLSADKTELISKGAGLAYPIRDGIPVMLESEARTLTTDERLDK
What are the official names of this protein?
UPF0434 protein PFLU_3771.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: CYTC_RAT
Sequence: MASPLRSLMLLLAVLAVAWAGTSRPPPRLLGAPQEADASEEGVQRALDFAVSEYNKGSNDAYHSRAIQVVRARKQLVAGINYYLDVEMGRTTCTKSQTNLTNCPFHDQPHLMRKALCSFQIYSVPWKGTHTLTKSSCKNA
What is the function of this protein?
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.  Known to inhibit cathepsin B, H, and L.
What are the official names of this protein?
Cystatin-C, Cystatin-3.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LRX4_ARATH
Sequence: MKNNTTQSLLLLLLFFFFFFEISHSLSISSNAPLSDTEVRFIQRRQLLYYRDEFGDRGENVTVDPSLIFENPRLRSAYIALQAWKQAILSDPNNITVNWIGSNVCNYTGVFCSKALDNRKIRTVAGIDLNHADIAGYLPEELGLLTDLALFHVNSNRFCGTVPHKFKQLKLLFELDLSNNRFAGKFPTVVLHLPSLKFLDLRFNEFEGTVPKELFSKNLDAIFINHNRFRFELPENFGDSPVSVIVLANNHFHGCIPTSLVEMKNLNEIIFMNNGLNSCLPADIGRLKNVTVFDVSFNELVGPLPESVGGMVEVEQLNVAHNLLSGKIPASICQLPKLENFTYSYNFFTGEAPVCLRLSEFDDRRNCLPGRPAQRSSRQCSAFLSRPSVDCGSFGCGRSVVKPSPPIVALPPPPPPSPPLPPPVYSPPPSPPVFSPPPSPPVYSPPPPPSIHYSSPPPPPVHHSSPPPPSPEFEGPLPPVIGVSYASPPPPPFY
What is the function of this protein?
Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization.
What are the official names of this protein?
Leucine-rich repeat extensin-like protein 4, AtLRX4, LRR/EXTENSIN4, Cell wall hydroxyproline-rich glycoprotein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: CLPX_HALHL
Sequence: MTDRTQNKGDDSGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELQEGAATEGGGLPRPHEINRELDQYVIGQEHAKKVLSVAVYNHYKRLESRTSQDDVELTKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQHGIVYIDEIDKVSRKADNPSITRDVSGEGVQQALLKLIEGTTASVPPQGGRKHPQQEFVQVDTSNMLFICGGAFAGLDKVIQERSERGGIGFSAEIKGEGERASVGETLQTVEPSDLVRYGLIPEFVGRLPVIATLNELDQEALVQILREPKNALVKQYQKLFEMEGVELDLRDDALRAVADKAMERKTGARGLRTIIEQVLLETMYELPSMENVSKVVVDESVIAGDSDPYIVYAGPEHSKAASDE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RIMO_ECODH
Sequence: MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPC26_MYCTU
Sequence: MIIDTSALLAYFDAAEPDHAAVSECIDSSADALVVSPYVVAELDYLVATRVGVDAELAVLRELAGGAWELANCGAAEIEQAARIVTKYQDQRIGIADAANVVLADRYRTRTILTLDRRHFSALRPIGGGRFTVIP
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB26.
What are the official names of this protein?
Ribonuclease VapC26, RNase VapC26, Toxin VapC26.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: Y1566_ALIF1
Sequence: MNLSAKTVVVIAIGAALYGIGGLPMFGIPVFANTTLKPAMAVLALFSVLYGPIVGFLVGFIGHWVTDLFAGWGVWLTWVLGSGIVGMIIGLFPIITKNRIESGLFDKKDFLIFVVLAFFGNVFGYGTSAFLDTILYAEPFTKVFMQLCIIAAGNTFLIAIVGYFILNNLAKRKKQSTNLTEAP
What are the official names of this protein?
UPF0397 protein VF_1566.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLO2_CALJA
Sequence: LLGVFHHTDLRKSLTVDEGTMKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVVEEAKKHGVMLTTVLTTHHHWDHAGGNEKLVKLEPGLKVYGGDDRIGGLTHKGTHLSTLQVGSLNVKCLSTPCHTSGHICYFVTKPGGSQPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRFPPDTRVYCGHEYTINNLKFARHVESGNAAVQEKLAWAKEKYSIGEPAVPSTLAEEFTYNPFMRVREKTVQQHAGETDPVPTMRAVRREKDQFKVPRD
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, mitochondrial, Germ cell-specific protein, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion matrix. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: PDUN_SALTY
Sequence: MHLARVTGAVVSTQKSPSLIGKKLLLVRRVSADGELPASPTSGDEVAVDSVGAGVGELVLLSGGSSARHVFSGPNEAIDLAVVGIVDTLSC
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Bacterial microcompartment shell vertex protein PduN, Bacterial microcompartment protein pentamer, BMC-P, Propanediol utilization protein PduN.
What is the protein family that this protein belongs to?
Belongs to the CcmL/EutN family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: VATF_METBU
Sequence: MELAVVGSSEFVTGFRLAGIKKIYEAKSDELESVVTKVLKDSDVGIFVIHEDDFNKLPEILRDTLSESVDPTVVTLGGTGESSNLREKIKQSVGVDLWK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: RS13_CHLT2
Sequence: MPRIIGIDIPAKKKLKISLTYIYGIGPALSKEIIARLQLNPEARAAELTEEEVGRLNALLQSDYVVEGDLRRRVQSDIKRLITIHAYRGQRHRLSLPVRGQRTKTNSRTRKGKRKTIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL19_STRP6
Sequence: MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFEGVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: LEUD_DESAH
Sequence: MKPFTTHTGVIATLNRSNVDTDAIIPKQFLKSIKRTGYGPSAFYDWRYTADGRPDPNFELNHPRFEGRSILVTRNNFGCGSSREHAVWALVQDGYRVIIAPWKEIGEKRLPAFADIFLSNTTKNGMLCIELSETIIDAIFEQTASQPGLQATVDLTVQQLTIHGRIPATYPFQIEEGVREQLINGLDEIALSLKHEADIAAFEARRPTWMDGRD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: FLIW_CAMJD
Sequence: MTLAVKCPILGFEETKNMEFSTIDEVFVRLKSLDGKDFSFVLINPYLIRPDYEFDIPTYYQELLSLTPESNMKIFNIVAIAKSIEESTVNFLAPVVINLDNNTMAQVILDTVNYPDFFQADQIANYIKK
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_MICLC
Sequence: MARIGESADLLKCSFCGKSQKQVRKLIAGPGVYICDECIELCNEIIEEELGEAAEADETVLPTPQEIFDHLESFVIGQEAAKRSLAVAVYNHYKRVRGPQARGGDLADRLTERDDLADVEVGKSNILMVGPTGSGKTYLAQTLARRLNVPFAVADATSLTEAGYVGEDVENILLKLIQAADYDVKKAEQGIIYIDEIDKISRKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFLQIDTSNVLFIVAGAFAGLDEIIGSRAGRKGIGFGAPLNHLGAGDVTYADVRPEDLLKFGLIPEFIGRLPVITTVEDLTHEQLVRVLTEPKNALLKQYQKMFLMDGVELEFEQDALDAVVAQAEARGTGARGLRSIMENVLKPVMFELPSRSDVGTVVISGDVVRGEAEPTLIPAEVERRRRGRSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: HTF_BLAGI
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, BlaGi-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNC_CHLTA
Sequence: MQHTVDIQAIESKLNFTFSHPRLLITALTHPSYRNEFPSAEEDSERLEFLGDAVLGLVVTEHLFLLFPALNEGLLSTTRAALVNAEACFEYTQKLSLGEHLLIGRGEKMQSHRGKISAYANLLEAILGAVYLDGGLSPARQIIVPLLPDKESILPLMLVNPKNRLQQFTQQTLKVLPSYKALPWKSEDGSPGYHVQVFVNGDLWGEGFAGSKKEAEKLAAKQALSTHDNKN
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXUA_SERP5
Sequence: MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIPNGEVWPIEEIKARQALLAEKGLVWSVVESIPVHEEIKTHSGNYQQHIAHYQQSLRNLAACGIDTVCYNFMPILDWTRTDLEYLLPDGSKALRFDQIAFAAFDLHILQRAGAEQDYTQEEQQQAAARFAAMSEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDAIDKAQLRENMAVFLRAIVPVAEEVGVRLAVHPDDPPRPLLGLPRIVSTIEDMQWFKQTVDSLHNGFTMCTGSYGVREDNDLVRMIETFGDRIHFTHLRATCREDNPKSFHEGAHLQGDVDMVAVIEAILSEEQRRHQTGDTRPIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAELRGVELALKRRFFPELP
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: TRPC_LACLM
Sequence: MNIKEGKFLETILAEKKQEIAQMPDENSKPIRQTYRLYDYLKKHSDQLQVIAEVKKASPSLGDINLEVDIIAQAKNYEQAGAAMISVLTDPVFFKGNIEYLREISKNVQIPTLNKDFIIDKKQINRALNAGATVILLIVACFENDFEKLEELYNYAISLGLEVLVETHNKAELDRAHQLAAKIIGVNNRNLKTFEVSLQNSTDLVPYFKEENVYISESGIFGKKEAQKVAENFNGILVGTALMQANNLTKSLTDLKIKRKNDEH
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ACMSD_MOUSE
Sequence: MKIDIHTHILPKEWPDLEKRFGYGGWVQLQQQGKGEAKMIKDGKLFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPELAVEEMERCVKALGFPGIQIGSHINTWDLNDPELFPIYAAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTMAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCAQDNPSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDKVMLGTDYPFPLGEQEPGKLIESMAEFDEETKDKLTAGNALAFLGLERKLFE
What is the function of this protein?
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS).  ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders.  In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite.  ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
What are the official names of this protein?
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, Picolinate carboxylase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.