PharMolix/UniProtQA huggingface dataset:
Protein: CAS2_FRAAA
Sequence: MFVVLVYDTAAERNPNALRTCRKYLHWVQRSVFEGELSAAQYRALMTTLRDQLDLTYDSIRVYRTRSPALVETEWLGVPLGNQDSVL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: RS7_SYNPW
Sequence: MSRRNAAVKRPVLPDPQFNNRLATMLVARLMKHGKKSTAQRILSDAFSLIGERTGGDPIELFETAVKNATPLVEVRARRVGGATYQVPMEVRQERGTAMALRWLVSFSRARNGRSMAQKLAGELMDAANEAGSAVRKREETHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RM33_YEAST
Sequence: MVFYKVTLSRSLIGVPHTTKSIVKSLGLGKRGSIVYKKVNPAIAGSLAKVKELVKVEVTEHELTPSQQRELRKSNPGFIVEKRTID
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L33, mitochondrial, Mitochondrial large ribosomal subunit protein uL30m, YmL33.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GDX_SHIFL
Sequence: MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMALLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKLSTH
What is the function of this protein?
Guanidinium ion exporter.  Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons.
What are the official names of this protein?
Guanidinium exporter.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIOB_METEP
Sequence: MSDTVVSLTASPAAIRHDWTLAEIQAIHDMPLLDLVHRAGVVHRAHNDPADIQRAALLSIKTGGCPEDCAYCPQSAHHKGANLPRERLMPVDAVLKEAAAAKANGAHRFCMGAAWRKPKDGPDFDAVLEMVRGVRGLGMEACVTLGMLTQSQAQRLAEAGLTSYNHNLDTGPEFYGDIISTRTYDDRLQTLEHVRQAGIGVCCGGIVGMGERVRDRAEMLLVLANHAPHPESVPINALVAVEGTPLEDRPPIDPLDLVRMCATARIVMPKARVRLSAGRKSLTREAQILCFLAGANSIFYGERLLTTANNEADADAELLRDIGVPVPEVTLAAAE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RL30_MYCS2
Sequence: MAELKITQVRSTIGARWKQRESLRTLGLKKIRQSVVREDNAQTRGLINTVHHLVEVEEVGK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: MRH4_YARLI
Sequence: MFANSLRRITKPCLGVPDMAVRHIAMRPKPKVKVNSREGGGKGKPRPSTGVRRKPPGAQKQQPASIAINGDAARRLLESKFAANISSFNELKLHPDVRAVLPDVIQLPEHKQDQDIKPSIIQSLAVKIMRQSYTYKQRVKNEGEEPTVEKIPVDRQKTFVLAAQTGSGKTLAYLLPLLSDLKDQEKFPSWQLEKHYKTVRSVILVPTLELSQQVGQVLKQFEEPLGIKTFASAFGQSHQEIAKAFNNRLDVLVTTPQKLQQTREKNLGGATHLVVDEADTLFDTNFIDSTTDVISQMPKLKCAAFVAATVSKSFLRKLRSFYPHVVVIAAPRLHAIPDHIRFSVVDVNKAPYYNNKKVALLQALYAISHSQKQKNYVRRVVVFRNRKEHIPELKKFLEENGYPVDTLHGKQDLHERNEVVEKYTNMPDAADQTENARNVRVLLTTDIASRGMDMKNLRFVVLYDVPFDKTDFIHRVGRTGRFGREGEVYMFTDNQDKKAQTNQLLHTSRNGLSL
What is the function of this protein?
ATP-binding RNA helicase involved in mitochondrial RNA metabolism.  Required for maintenance of mitochondrial DNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase MRH4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. MRH4 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FABP_TYRPU
Sequence: MVQLNGSYKLEKSDNFDAFLKELGVNFVTRNLAKSASPTVEVIVDGDSYTIKTSSTLKNSEIKFKLGEEFEEDRADGKKVQTSVTKEGDNKLVQVQKGDKPVTIVREFSEEGLTVTATVNGVTSVRFYKRQ
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
What are the official names of this protein?
Fatty acid-binding protein, Allergen Tyr p 13.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: TNNT3_COTJA
Sequence: MSDTEEVEHGEEEYEEEEEVQEEEVHEPAPPPEEKPRIKLTAPKIPEGEKVDFDDIQKKRQNKDLIELQALIDSHFEARRKEEEELVALKERIEKRRAERAEQQRIRAEKEKERQARLAEEKARREEEDAKRKAEDDLKKKKALSSMGASYSSYLAKADQKRGKKQTARETKKKVLAERRKPLNIDHLNEDKLRDKAKELWDWLYQLQTEKYDFTEQIKRKKYEILTLRCRLQELSKFSKKAGAKGKVGGRWK
What is the function of this protein?
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin T, fast skeletal muscle isoforms.
What is the protein family that this protein belongs to?
Belongs to the troponin T family.
Protein: RPOB_RALPJ
Sequence: MAYSFTEKKRIRKSFAKRATVHQVPFLLATQIQSYAQFLQENAPVAQRKSEGLQAAFNAIFPIVSHNGLARMEFVSYHLSNPPFDVKECQQRGLTFHSALRAKVRLIINDRENPTKVKEIKEQEVYMGEIPLMTSTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVFDNFTLKTEGALMEFVPERLRGEVARFDISDKNGKVVVEKDKRINAKHIRDLDSAGTKLISVPEDYLLGRVLAKNIVDPDTGEVLANANDELTEGVLEKLRDAGVKEIQTLYTNDLDQGPYMSATLRTDDTADQTAARIAIYRMMRPGEPPTEDAVEALFQRLFYSEDSYDLSRVGRMKVNSRLNRSSGTGPMVLTDEDILDTIKLLVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLSRVERAVKERLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAQLNDYGFLETPYRKVENGKLTDQVDYLSAIEEGKYVVAQANATLDKDGNLIDELVSAREGSERETRMVTPDRVQYIDVAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRADKPLVGTGVERTVAVDSGTAVQATRGGVVDYVDANRVVIRVNDAEAVAGEVGVDIYNLIKYTRSNQNTNINQRPMVKVGDVVARGDVIADGASTDMGELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIGAEVEAGDVMVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGVVRDKRAQSIIDEELKRYRLDLNDQLRIVEGDAFQRLERLLVGKIANGGPKKLAKGTALTKEYLADLDKWHWFDIRPAEDEVALQLEAVKVAIEQKRHDFDLAFEEKRKKLTQGDELPPGVIKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKITPIEDMPYMADGTPADIVLNPLGVPSRMNVGQILETHLGWAARGLGERIGNMLKAQAKAAEIRKLLGQIYNESGKVEDLDSLSDAEILELAENLKKGVPFATPVFDGAHEDEIRRMLDLAYPEDIAKEKGLTASKQQVTLFDGRTGEAFERPVTLGVMHMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLGIDIDLERN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: UXUA_ECOL6
Sequence: MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: ACKA_STRP1
Sequence: MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP2DA_RAT
Sequence: MELLNGTGLWPMAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDPSNMPYSMYKLQHRYGDVFSLQMGWKPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVVFASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKEAGHLCDAFTAQNGRSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMLTLVEESLIEVSGFIPEVLNTFPALLRIPGLADKVFQGQKTFMAFLDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQHFSFSVPAGQPRPSTLGNFAISVAPLPYQLCAAVREQGH
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2D10, CYPIID10, Cytochrome P450-CMF1B, Cytochrome P450-DB5, Debrisoquine 4-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: BRK_POLMJ
Sequence: KRRPPGFTPFR
What is the function of this protein?
Induces relaxation of arterial smooth muscle, by targeting bradykinin receptors (BDKRB) (By similarity).  May cause hypotension.
What are the official names of this protein?
Wasp kinin PMM1, Bradykinin-related peptide.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPAT7_RAT
Sequence: MAVHYNKILSAKAAVDCSIPVSVNASIKYADQQRREKLRKELARCEKEFKLSKSAMQTNSKMNSKFFVNSLQRPSGEPQDQDVLIEERLTRYPSFSKSLIPSPEGLHLSLPESNKILMNGTQKYPSTAPPRYSGCGHGYDRRPRSAHQFQVVISKTPSGDLLEKHADLFSNNQSPFTPRTLKTEAKSFLSQYRYYTPAKRRRDFSDQRMEAETQTELSSFNSELGTAEKKSSKDSDVSIKQAPNYMRNGAEDKIAPLSLQGQNLAWDKSKDGILQPSSERAPCTQFSPDSKIYSDEEELLYLSFMENVTDEILKLGLFSNRFLERLFERHIRKNKHHLEEGKMRYLLHGLKVDLGCISEEEQNSFRIFNEFHFQKALTSRENRFINDTEAVNHHERQQYQEALNMLSSVPKDENKMFSFPGEFLLPAHKVKHSEGVIVQQVNDETDFEALPWDGNNPSVSDSFIDQETSVDVIEGDSDFEMVETSRELCCLSTSLSPSVPLPSIEGGSNHDKELSTLKIMEMSIED
What is the function of this protein?
Involved in the maintenance of both rod and cone photoreceptor cells (By similarity).  Required for photoreceptor-specific localization of proximal connecting cilium (CC) proteins RPGR, AHI1, NPHP1, NPHP4, and RPGRIP1 at the distal CC, a photoreceptor-specific extension of the primary cilium transition zone (By similarity).  Maintenance of protein localization at the photoreceptor-specific distal CC is essential for normal microtubule stability and to prevent photoreceptor degeneration (By similarity).
What are the official names of this protein?
Spermatogenesis-associated protein 7 homolog, Fertility-related protein WMP1, Rat sperm DNA no.3, RSD-3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton. Cell projection, cilium, photoreceptor outer segment. Note=Localizes to the microtubule network.
Protein: GCST_ECOL6
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTIAWEPADRDFIGREALEAQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: PARP1_MOUSE
Sequence: MAEASERLYRVQYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGQSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVAGKGQDGSGGKAEKTLGDFAAEYAKSNRSMCKGCLEKIEKGQMRLSKKMVDPEKPQLGMIDRWYHPTCFVKKRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAIKNEGKRKGDEVDGTDEVAKKKSRKETDKYSKLEKALKAQNELIWNIKDELKKACSTNDLKELLIFNQQQVPSGESAILDRVADGMAFGALLPCKECSGQLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKEFREISYLKKLKVKKQDRIFPPESSAPITVHWPLSVTSAPTAVNSSAPADKPLSNMKILTLGKLSQNKDEAKAVIEKLGGKLTGSANKASLCISIKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQDLLSAHSLSPWGAEVKAEPGEVVAPRGKSAAPSKKSKGCFKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKESRYWIFRSWGRLGTVIGSNKLEQMPSKEEAVEQFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKPVQELVGMIFDVDSMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQPVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLIMLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSASITLEGVEVPLGTGIPSGVNDTALLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW
What is the function of this protein?
This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.
What are the official names of this protein?
Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, DNA ADP-ribosyltransferase PARP1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, msPARP, Protein poly-ADP-ribosyltransferase PARP1.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome. Note=Localizes to sites of DNA damage.
Protein: RS16_PROMS
Sequence: MIKLRLKRFGKKKEASFRIVACNSTSRRDGRPLQELGFYNPRTKETRLDTEALRTRLTQGAQPTDVVRTLLEKGGLLEKTERPSIAIGKAKLEKEKLAKAKTKDEENDNSKVESEGNEAES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SSAL_SALTY
Sequence: MVKIKEVAMNIKINEIKMTPPTAFTPGQVIEEQEVISPSMLALQELQETTGAALYETMEEIGMALSGKLRENYKFTDAEKLERRQQALLRLIKQIQEDNGATLRPLTEENSDPDLQNAYQIIALAMALTAGGLSKKKKRDLQSQLDTLTAEEGWELAVFSLLELGEVDTATLSSLKRFMQQAIDNDEMPLSQWFRRVADWPDRCERVRILLRAVAFELSICIEPSEQSRLAAALVRLRRLLLFLGLEKECQREEWICQLPPNTLLPLLLDIICERWLFSDWLLDRLTAIVSSSKMFNRLLQQLDAQFMLIPDNCFNDEDQREQILETLREVKINQVLF
What are the official names of this protein?
Secretion system apparatus protein SsaL.
Protein: KDSB_ECOHS
Sequence: MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_STRP2
Sequence: MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAVVGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRVWMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSSKELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAC1_ASPOR
Sequence: MSCDMEKTMSSVDSLPATPASEVPVLTVSPADTSLNSADVKTQEVKPEEKKPAKKRKSWGQELPVPKTNLPPRKRAKTEDEKEQRRIERVLRNRAAAQTSRERKRLEMEKLENEKIQMEQQNQFLLQRLSQMEAENNRLSQQLAQLAAEVRGSRANTPMPGSPATASPTLTPTLFKQERDELPLERIPFPTPSLSDYSPTLKPSTLAESSDVAQHPAVSVAGLEGDGSALPLFDLGSDLKHHSTDDVAAPLSDDDFNRLFHGDSSVEPDSSVFEDGLAFDVLEGGDLSAFPFDSMVNFDSEPVTLEGIEMAHGLPDETTCKTSSVQPGFGASTTRCDGQGIAAGC
What is the function of this protein?
Transcriptional activator involved in the unfolded protein response (UPR) pathway.  Recognizes and binds to the UPR element (UPRE) in the promoter of UPR-regulated genes.  Increases the synthesis of endoplasmic reticulum-resident proteins required for protein folding as well as components of the secretory pathway (By similarity).
What are the official names of this protein?
Transcriptional activator hacA.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSU72_GIBZE
Sequence: MEVANGSSAAQGQNGSSEGSNGYKLKFCTVCASNNNRSMEAHLRLSQADYPVISFGTGSLVRLPGPTITQPNVYHFNKTSYDSMFKELESKDARLYKNNGILNMLNRNRGVKWGPERWQDWQVGVPRLQHAKDRGSEGTEGGLVDIVITCEERCWDAVVDDLMNRGSPLNRPVHVINVEIKDNHEEAAVGGQGILDLANSLNAAAREERDAVGASAFDNGSASSRATFDERVPDILASWQERWPNLPATWTVAWF
What is the function of this protein?
Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  SSU72 is required for 3'-end formation of snoRNAs (By similarity).
What are the official names of this protein?
RNA polymerase II subunit A C-terminal domain phosphatase SSU72, CTD phosphatase SSU72, Suppressor of SUA7 protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SSU72 phosphatase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUC_ANAD2
Sequence: MSKRSDGSQPRTIVDKVWDAHVVRAETPDAPAILYIDLHLVHEVTSPQAFTVLRERGLKLRRPERTLATMDHSIPTLPRGADGRWPFVDAQAAAQVSQMERNCADFGVELHGLGDDAQGVVHVFGPEMGATQPGMTVVCGDSHTATHGAFGALAFGIGTSEVGHVLASQCLLQRRPRTLAVRVDGELGPGLSAKDLILAIIAKLGVGGGTGHVIEYLGPAVRALSMEGRMTLCNMSIEAGARAGLVAPDDTTFEWLAGRPRAPKGAAWDEAVARWRALPSDDGATYDRELRLDAAALEPMITFGTNPGQGIAVTGLVPDPVAERDASARATLEAALRYMGLVPGKPIAGQKVDVVFIGSCTNGRIEDMREAARVLKGRKVRTRTLVVPGSHRVKKDAEAEGIDRIVREAGAEWREPGCSMCIAMNGDNLQAGQYCVSTSNRNFEGRQGPGGRTLLASPLTAAAAAVTGAVADPRRVLEGR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: KAD_CAMJJ
Sequence: MKELFLIIGAPGSGKTTDASLIAQADATNITHYSTGDLLRAEVASGSELGKTIDSFISKGNLVPLDVVVNTIVCALKAAPTKTIIIDGYPRSVEQMMEFDKVLSEQNEICLKGVIEVRVSEEVAKERVLGRNRGADDNEEVFYNRMKVYTEPLNEILDFYQKKKLHFIIDGERTIEPIVADMKELIKKIQSI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_BURP1
Sequence: MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIAAHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGDQEAIAKAQAAVAQQGKSAA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: MTBC2_VITVI
Sequence: MGVPSEGAVGNVNGNEVGTTASFAGYMETRGVREARVLASELCRHMYTLGWFSGTGGSITIKVHDDSIPKPRQLVVISPSGVQKERMVPEDMYVLSSDGFILSTPPLKPYPHKPPKCTDCTPLFMKVYEMRDAGAVIHSHGMESCIVTMILPFSKEFRITHMEMIKGIKGHGYHDELVVPIIENTAHEAELVESLTEAITAYPKTTAVLVRNHGVYVWGDSWISAKTQAECYHYLFDAAIKLHQLGLDWSTPTHGPIRSINGIWGCNGTMSRGLKVGGLSLDDMIEPSQRCILLDIEGTTTPISFVTDVLFPYAHANVGKHLAATFDSEETQDDINLLRSQIQHDLEHGVVGAVPIPPDYVGKELVIASFVANVEAMIRADRNITALKQLQGHIWKTGFQSNELVGVVFDDVPEALERWHASGIKVYIYSSGSREAQQLIFSNSNYGDLRKYFCGFFDTTMGNKKETHSYFEILRTVGIDRPSDMLFVTDVFQEAVAARAAGLEVVISIRPGNGPLPENHGFRTIETFLEI
What are the official names of this protein?
Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: TRMA_SHISS
Sequence: MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPCILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: URK_MANSM
Sequence: MSDSANSSCIIIAIAGASASGKSLIASTVHRELRDQVGSDDISIISEDCYYKDQSHLDFATRTQTNYDHPNSMDRDLLLEHLRALKAGKSVDIPQYSYVEHTRMKEVTHFTPKKVIILEGILLLTDERVRNELSLSLFVDAPLDICFIRRLKRDMEERGRSLESVIEQYRKTVRPMFLQFIEPSKQYADIIIPRGGKNRIAINMLKAQILHLLGRK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.