PharMolix/UniProtQA huggingface dataset:
Protein: VP7_ROTHM
Sequence: MYGIEYTTILIFLISVILLNYILKSVTRIMDYIIYRSLLITVALFALTRAQNYGLNLPITGSMDTIYANSTREGIFLTSTLCLYYPTEASTQISDGEWKDSLSQMFLTKGWPTGSVYFKEYSSIVDFSVDPQLYCDYNLVLMKYDQNLELDMSELADLILNEWLCNPMDITLYYYQQSGESNKWISMGSSCTVKVCPLNTQTLGIGCRTTNVDSFEMVAENEKLAIVDVVDGINHKINLTTTTCTIRNCKKLGPRENVAVIQVGGSNVLDITADPTTNPQTERMMRVNWKRWWQVFYTIVDYINQIVQVMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: ISPE_SALA4
Sequence: MTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRRDGEIHLLTPVNGVENEDNLIVRAARLLMKAASESGRLPAGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVNPPEKWYLVAHPGVSIPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTGACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RU1C_PHYIT
Sequence: MPRYYCDYCDTYLTHDSQAGRKQHNRGWKHRENVKLYYEQFLAGQGVIMNPGEWLRGPAPMGSLPPRPNGPMNGGMPGGYPPRGVPPRGMMPPPGPVMRPPMFRGPPRGPPPMGAMGMRGPPGPGAMGGPPPRSIYGP
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECB_POLSJ
Sequence: MAEANLDPVFQIQRVYLKDVSLEQPNSPEILLNQEQPGVDIQLGVDAKPVADGMFEVTVTATVHTKIADKTVFLVEAKQAGIFEIRNMQTDQLGAILGIACPQIVYPYLRSNVADVIQRGGFPPVHMAEINFQAMYEQQQAEAATPQIIV
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GACP_DICDI
Sequence: MKNFKAKIITAKQNVMEKTAKRENTLEPDEMKELEKKTTETKDFLRKLTKSVEKETLSSGVSIQDGTELADNFLDYSVHVRDNQSDLVILSGILSKIGEFQAGFEDLKSKLNSSLINDVSDPLKSIIKTELKQAKESKREYDRVRVAFDAHLSELANLRKQKNVKPPKIQESEEECERLRTNFERVGIDTTCLLRDTNVITEFETVEKLCDYLDSYHTFFQKGYRWLAQMIPDIYEYRLYVEKRKAELEKSKVRISMMVSPQKQQADSLSKTKCFGEDLSVLLNREGSTLPWFIVRAFQAIRNHIATEEGLFRLSGTKRIIYEYKQKIDEGKEYNLSEILDIHVVCNLVKLYLRELQPEPLLTYSRYNELIDTCNIEDQNQRVDKISKILSSLPKHYYTLLHHLIHLLSQIASQPKSKMGPANLATVIGPNILICQTDVVLEDIALGNMVVTTIIQNFDRIFGGPPLLQQSVPDTYVPPPNNTRNNSVNNFNNVQPSSFSASTSRSINLNKSTNNPNINDDNNNNNNINNSDDEPYDPNAPPIYSGVPMRGNIKHSDSCSTLGDSFDEGDAVELSD
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacP, GTPase activating factor for raC protein P.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_CHRVO
Sequence: MGKIIGIDLGTTNSCVAVVEGGNPKVIENAEGNRTTPSIIAYVEDGEILVGAPAKRQAVTNPKNTIYAAKRLIGRRFEDKEVQKDIDLMPFEILKAKNGDAWVKVRDQELAPPQISAEVLRKMKKAAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGLAKQEGDRKIAVYDLGGGTFDVSIIEIADVDGEHQFEVLSTNGDTFLGGEDFDQRLIDYIVTEFKKEQGVDLKQDVMALQRLKEAAEKAKIELSSATQTEVNLPYITMDATGPKHLAMKITRAKFESLVDDLIARSIEPCRVALKDAGVSLSDITDVILVGGQTRMPKVQDAVKEFFGKEPRKDVNPDEAVAVGAAIQGSVLSGDRKDVLLLDVTPLSLGIETLGGVMTKLIQKNTTIPTKASQTFSTADDNQTAVTIHVLQGEREKAAANKSLGQFNLGDIPPAPRGIPQIEVEFNIDANGILHVSAKDKATGKQANITIQASSGLSEAEIERMVKDAEANAEEDKKLHELVTARNHAEGLIHSIKKSLGEHGDKIGADEKAKIESALKEAEEVVKGDDKEAIEAKAEELAKASQKLGEIMYAQAQAEAGAQGGAEQAEAGKKDEGNVVDAEFEEVKKDKA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS21_SYNAS
Sequence: MEVKVFDNDVEKALKILKNKLSKSGLFKELKVRRAYEKPSVKRKRKAIEARRRFAKVQRRRSS
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: XTH23_ARATH
Sequence: MAMISYSTIVVALLASFMICSVSANFQRDVEITWGDGRGQITNNGDLLTLSLDKASGSGFQSKNEYLFGKIDMQIKLVAGNSAGTVTAYYLKSPGSTWDEIDFEFLGNLSGDPYTLHTNVFTQGKGDREQQFKLWFDPTSDFHTYSILWNPQRIIFSVDGTPIREFKNMESQGTLFPKNQPMRMYSSLWNAEEWATRGGLVKTDWSKAPFTASYRGFNEEACVVINGQSSCPNVSGQGSTGSWLSQELDSTGQEQMRWVQNNYMIYNYCTDAKRFPQGLPRECLAA
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
What are the official names of this protein?
Probable xyloglucan endotransglucosylase/hydrolase protein 23, At-XTH23, XTH-23.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 2 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: TLP_BACC4
Sequence: MPNPDNRSDNAEKLQEMVQNTVDNFNEAKETAELSNEKDRAAIEAKNQRRLESIDSLKSEIKDES
What are the official names of this protein?
Small, acid-soluble spore protein Tlp.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
What are the subcellular locations of this protein?
Spore core.
Protein: CH10_LISMH
Sequence: MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLDNGTKEPLEVAEGDTVIFAKYSGTEVTYEGTDYLILRESDILAITK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_TERTT
Sequence: MSNQDEPQNSPEEFAEDQQADVALEEASSDSSETAADVDLVARIEALEAELTEAKEQALRAAAEMHNVRRRAEQDVEKAHKFGLEKFVSDMLPVADNLGRALEAAAAEGADMTAVTEGVDLTLKSLMDSLKKHGVESVNPEGEPFNPELHQAMTAVENPDAEPNTVINVYQVGYTLHGRLVRPAMVVVSK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTS_SALTI
Sequence: MNRQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFIGLMVGGVLADRYERKKVILLARGTCGIGFIGLCVNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMLGGILLASGGVAWNYGLAAAGTFITLLPLLTLPRLPVPPQPRENPFIALLAAFRFLLASPLIGGIALLGGLVTMASAVRVLYPALAMSWQMSAAQIGLLYAAIPLGAAIGALTSGQLAHSVRPGLIMLVSTVGSFLAVGLFAIMPIWIAGVICLALFGWLSAISSLLQYTLLQTQTPENMLGRMNGLWTAQNVTGDAIGAALLGGLGAMMTPVASASVSGFGLVIIGLLLLLVLGELRRFRQTPPVSDAG
What is the function of this protein?
Component of an export pathway for enterobactin.
What are the official names of this protein?
Enterobactin exporter EntS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LI2P2_ARATH
Sequence: MVFSVATSSVTNPKLHHHHHLSDFNRNRVSTSLKIMNSKNHTNPRKCECFDLYDQLIPYKKAWSWQKSILNEKKALIDKNQECSDSLIILQHPSVYTMGTGSSENYLNFDIKNAPFDVYRTERGGEVTYHGPGQLVMYPIINLRNHKMDLHWYLRKLEEVVIRVLSSAFAINASRLDGFTGVWVGNKKMAAIGIRVSKWMTYHGLALNVTTDLTPFNSIVPCGIRNRGVGSVKGLIEDGEHYNKLEDLQLLDIAHESLLKEFSEVFQLQMEKQTVFKLEC
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) (PubMed:23581459).  Together with LIP1P is essential for de novo plastidial protein lipoylation during seed development.  Acts redundantly with LIP2P (PubMed:23581459).
What are the official names of this protein?
Octanoyltransferase LIP2p2, chloroplastic, Lipoate-protein ligase 2p2, Lipoate-protein ligase-like protein, Lipoyl-[acyl-carrier-protein]-protein-N-lipoyltransferase-like protein 2p2.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LRC42_XENTR
Sequence: MFQCLEPERNEETGPVYVRERGKLSVVGSHVSELRTRPCRLFSKGFSVELCGKQEDTSRHRQKPFIFTYTKEGSLRYSAKSLFTLTLDLITDNIHYVDSLMGFPDQIAEKLFTAAEAKHKFFTPCNGVMALRKFTEAYGDLVLSSLCLRGRYLLISERLEEIKSFQCLRSLDLSCCKLGDEHELLEHLSSDPMSSLTELYLKDNCFSDTGIRKMTASLRVLGKGLDALKVLDLSSNPGITDRGVLFLFGFKLLQFLDLSDTSIQDRSRTVKKIETKIGLVLSKKPIIQFEHRNCRTQGWAEQLLDQWENYIFSAIKPKDTLKSRKAAQQFYGKETKQNPLDSGICTLLTPVEQKQTHLQFFRPEEQKDSDSSKSDKRQRSTKRTGADPGQEDCTIAPATKRPRVTLTAADWDLLNSY
What are the official names of this protein?
Leucine-rich repeat-containing protein 42.
What is the protein family that this protein belongs to?
Belongs to the LRRC42 family.
Protein: CBPB2_BOVIN
Sequence: MKLYSLGVLVATVLFCGEHAFAFQRGQVLSALPRTSRQVQILQNVTTTYKIVLWQPVAAEYIVKGYEVHFFVNASDVSNVKAHLNASRIPFRVLVENVEDLIRQQTSNDTISPRASSSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAMWIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRRNIKHIKAYISMHSYSQKIVFPYSYSRSRSKDHEELSLVAREAVFAMENIHRNIRYTHGSGSESLYLAPGGSDDWIYDLGIKYSFTFELRDKGKYGFLLPESYIRPTCSEALVAVAKIASHVVKNV
What is the function of this protein?
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities.  Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.
What are the official names of this protein?
Carboxypeptidase B2, Carboxypeptidase U, CPU, Plasma carboxypeptidase B, pCPB, Thrombin-activable fibrinolysis inhibitor, TAFI.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NANE_BORAP
Sequence: MIIIEKIKRGLIVSCQALENEPLHSSFIMSKMALAAKMGGAIGIRANGVNDISQIKLEVDLPIIGIIKRNYNNCDVFITPTMKEIDELCNEGVDIIALDATFRNRPDSVSLDDFFKSIKKKYPKQCLMADISSLDEAINADKLGFDFIGTTLYGYTKSTNGLDIADNDFNFLKTLINSNLKSTLIVEGKIDTPLKAQKCFEMGVDLVVVGGAITRPVEITKKFVEKINQVKR
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: RS11_HELPS
Sequence: MAKRNVTAKKKVVKKNIARGVVYISATFNNTNITITDEMGNVICWSTAGGLGFKGSKKSTPYAAQQAVESALSKAKEHGVKEVGIKVQGPGSGRETAIKSVGTTEGVKVLWIKDITPLPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: LONP2_NEUCR
Sequence: MAHIRAPTVTIPLLPLPKQTVLLPGVVQRVAVSSTRPDIASLLAAVYAKAASQTPNGRIDTIPIACVPLASPLIGPEGHLLIENGDDKTETADDVDPAKATKADLFPYGVAAKITGVEGRGTGEFTLLVEGVTRIHVEKVISDKAYLEGKVSSYADPALITDAALEELFMSLKLLSRQFVTILRLSSLLPQSSGTPGLSPLLARRLDFYIAKQKYPGALADFMANIVESSYEEKLEILTLIDVKERVAKVIELLDRQITNIKNSMRVTTITATTLPFPMDPDAAKHGKIKPPVKAPGHGAGMPFSPQGGFMGRGGNADEDQEPNEIEELQKRLDAARLSPEAAKVADREIKRLKKIHPAQAEYAVTRTYLETLAEIPWTTTTDDRLGPDTLNRARKQLDEDHYGLDKVKKRLLEYLAVLRLKQAINDDVDSQIKQLEQELGVASESSKEDAAQSTPIDLGVDEKAKAGGDKLEALKSRRMVDKSPILLLVGPPGVGKTSLARSVATALGRKFHRISLGGVRDEAEIRGHRRTYVAAMPGLIVQGLKKVGVANPVFLLDEIDKVGGSSIHGDPSAAMLEVLDPEQNHNFTDHYVNVPIDLSKVLFIATANSLDTIPAPLLDRMETIYIPGYTTLEKRHIAMRHLVPKQLRVNGLDESQVSFTPEVVSRIIESYTREAGVRNLEREISSVARGKAVEFADAKDSGHPENYNPQLTVDDLEKFLGIEKFEEEIAEKTSRPGIVTGLVAYSSGGNGSILFIEVADMPGNGSVQLTGKLGDVLKESVEVALTWVKAHAYQLGLTQSPSENIMKDRSIHVHCPSGAVPKDGPSSGISQAIALISLFSGKAVPPTMAMTGEISLRGRITAVGGIKEKLIGALRAGVKTVLLPAQNRKDAKDLPQEVKDGLEIIHVSHIWEAIRYVWPDGQWPSEHDYPSIESRL
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix.  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: PPDEX_ARATH
Sequence: MWVPTLSSSSCSSDERDESSGEAALTPVYLNVYDLTPVNNYLYWFGIGIFHSGIEAHNLEYCYGAHEYPTSGVYEVEPRNCPGFIFRRSVLLGTTSMSRSDFRSYMEKLSRKYHGDTYHLIAKNCNHFTEEVCLQLTGKPIPGWINRLARVGSFCNCLLPESIQLTAVSALPERLEFSDEDESNSEASSVSDEEGSEQHLINVADREIVYLQNKPVRLTREEIP
What are the official names of this protein?
DeSI-like protein At4g17486.
What is the protein family that this protein belongs to?
Belongs to the DeSI family.
Protein: HUTG_LEGPA
Sequence: MFDDLSNYRPANPALWQGRMDTANQERFFQKITFIDNQNELMTKDKKTIFLGFASDAGIKRNLGRTGAKLGPDQIKTQLAKLPCHNNKHYVDLGNVVCENDELELSQSQFAQIVHFCHENGHQICAFGGGHEIAWAHYQGLSSLYPKLGVINFDAHFDLRPYKKGEFGNSGTPFSQIATYCEEKKMPFHYCCIGVQKFGNTPSLFEKAKELNVSYLSAEDLYEQSQAWQIAFLDDFILNLDHIYLTICLDVLAECYAPGVSAPQALGLSPWQIMPLLKYLIQSGKVVSLDIAELSPPLDSELKTARLAALIIAELLDTN
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: VP2_BECNB
Sequence: MASAATAGLTLLSGGAGIAADIASIVTEQQRLALQKEQIRNNYELGKQTLSLQQQAMENSRDRIRLSAAQIKELGLDPKSELSMIMGLTAGAQPSISAPISSEQLFLNSSNLARSVRWDARNFGEAINTFAGLRAKHQANPSRPDMMLGSDNPNWGARVTGDALSVSGLSVRSNHFGSGSSSLGSLSSVRTNPFSSVSSGSVGGISLRTVGSRPSIRSVFSTTSV
What is the function of this protein?
Minor structural protein present in one or two copies per virion.  Does not seem to play a role in capsid assembly, but is essential for production of infectious virus (By similarity).
What are the official names of this protein?
Protein VP2, Minor capsid protein.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RL1_LACGA
Sequence: MAKHGKRYLEAAKKVDSTKFYSVDEAMKLAKETSYANFDATIEVAYNLSVDPKQADQQIRGALVLPNGTGKSKKVVVFAEGPQADQAKEAGADEVGSDDLVEKVQNGYLDFDVVIATPMMMAKVGRLGRILGPKGLMPNPKTGTVTMDVAKAVENQKAGQVEYRVDKQGLIHAPIGKASFDADKLAQNFDALRDVILRARPASAKGQYIKSVAVSATFGPGIHLDPLNLD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MED8_DANRE
Sequence: MQQREEKQLEAFLESLVARVAHLKGSLQSFIYKLENEYDRLTWPSVLDNFALISGQLNTINKLLRNEKTPSYKSQVIIPLLLSPDRDEELAKLTEHRVPVFSHEIVPDHLRTKPDPEVEEQEKHLSAEAARIGPEVAQKQIQALNKLCSNLLEKLNNPREDRDSETSALRQNKPSFNPADTNALVAAVGFGKGLSKCRPPGPVAPGHPGQPMMQTGPTLQQVTIAGASGHQAGMSGPVAPQQPGQPGKIPSNIKTNIKSASMHPYNR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8, Mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROE_THEKO
Sequence: MADAETRLYGVIGFPARHSLSPVMHNAAFRALGINAVYLAFEVPPEELGEAIGGAKALGISGLNVTMPHKEAVIHFLDSLSEDSGEIGSVNTVVNRKGRLEGHTTDGLGARRALERAIELGGRRILIIGAGGAGKAIAYELSRDNEVVVLNRTPEKAKALERFGITGDALNRENLGEYLEWAEVLINATSVGMNSWETPVPAELLRRDLVVMDIVYKPLKTRLLTEAELRGCKTVDGLWMLVYQGIESFRLWTGFKPDEGLMRGAALEGISE
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GBAS1_CAEEL
Sequence: MRSVRSSSRTPKPVKRFVFDEDEDLEEIDLDEVDNADFEREDDEEEVLSEPSESPYTSTPKSSKRVNKTRGTKDFFKKDESLQLFRFVLNECRSQKPGRVGRVAKKRVGVNSMKYWERYKREIQGYRLPKQYRYHYSFYSKCFYKVLGLTPEEKVDLYYACEMPVVTDAEKQWLVEQFHVEFDEFGVIIGSDVCTHWDEEHSDSEDDSGKKEEKAREVSRYTEYHDDMMWKFIVDKISEGAQPIIDKHPIWDEFVKLNEENDVISKKSGRNHYDRFRRILVPNLHFMPYDDFTKAVLYERLEYPIPEEYRKILFTTTGADINESGFIEYLPPSTIHQISPIVPIPCHKSNPKFSQLKEPKDLILWSERKKFTPREDSQIWEFVRRKCVDSAGIFVKNDVLRGRGTLFFKDFRNTERKYESITQRFVVLRKLIMDTDYSLKQKLEIYYAISQPVDEDALDAFKSIACLVLNPDGTIRFAISKSFLIGRISDEPAKLEAENYSYVYDLFIFNETFGTAENPEPLCSVSQNRAEKFMLVSQLVFRFISRFEALEDRRIAWITPNAQVAPKEPVPAPSKKKSAFEAYQSSPQTFDTIQRFSTKRPFFCGDNFQIPPKKPFLAEEDVKLEPMEYENSEQIVENAEIKLEPAEELLDAETVTVEEFLMNSYSTAAPSTSTAPAPPKAPVTAPPAPQKSAQLLGKIDFAIGKMRENFDRFLQFAQQNSADLTVVQRYRYDAQMQQMTEKFTKDVSKVLSGDSIKR
What is the function of this protein?
Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates G-protein alpha subunit goa-1.
What are the official names of this protein?
G-protein alpha subunit activating protein gbas-1.
Protein: Y113_MYCPN
Sequence: MNVYQTIANFGTNILESLGLEAALSPTLSNTYIYGIPVLGAIFSGLITKKLTKSTAKSLIVQALFVILGTLAFLVITLASPAKPETGAFNQATLWIAFVVICFIMFFIGANRSIFWSTITELKVNKEIVGLAVGFISIIGFSKDVWLSPLLTGTTNQFIVKNSQGTSFYSQQALVAWAIFALINACLALLVTYMIVRKVKYGKVWVNPKFKKVFALGEQQYGH
What are the official names of this protein?
Uncharacterized protein MPN_113.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATB_CANDC
Sequence: MFLNAEFFFFFFQISISYIRLSQVSMFVRRLHKFSYNPNYKFKCGLEIHTQLKTKYKLFSLSPTSYNEPPNTKLSYFDVGLPGTQPLLNPEALLLALKASVALNCEIQSHSSFDRKHYFYADQPLGYQITQHYYPLAKNGYVQLNKFDDVPDKVITLEQVQLEQDTGKTVNYDDRINVDLNRANTPLIEVVTKPDFENIDQVQAFVRKYQLLVRHLDICTGDLETGAIRVDANISVNDNPRVEIKNLGSSGEIVDALKYEYNRQVTLLQNNETIVQETRGWNGTGTESLRKKENAVDYRYVPDSELPVIRLDSHIQEQLENTLDELPDSVLDRLTKEPYNLQLAHARNLLFQPEVLNYYENIFGRIRDANKWFFHELLAAFAKSDVQFQVDIVSTNMLVDIVSAVEKNEISLTGARIILKHIIRNKSFSTLPHLIKELDIGKPEASAELDDTINEICQQIINTNADVVEKIARGHANALQVLIGQAMKATKGKVHAKEFRSKFMELLNQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UGT50_CAEEL
Sequence: MHYSQMRWMFFCLTALLHGSFIVNAAKILVYCPSISKSHVLLCSKYADLLHNAGHDTVLFIPSYSKLLDNYDGAKHAKVWRLHNVTEAYDTKLGTLANVMENSHIGFIDRLTFDADFWIDMCADLLGKLPEMQHIIDYKFDLVIYNEIDPCTPAIVRLFNIPKTVLLSSEAIMDKVAWNLGLPTLPSYVPSVEENPNHDRMSFFERMSNVYKFFQSIVVHYLQDIHVLNLFRKEVSSDFPSIAEIIRNVSLVLVNTDEIFDLPRSYSSKFVYVGMLEAGKDENVTLPKKQDDYFKKGKSGSVFVSFGTVTPFRSLPERIQLSILNAIQKLPDYHFVVKTTADDESSAQFFSTVQNVDLVDWVPQKAVLRHANLKLFVSHGGMNSVLETMYYGVPMVIMPVFTDQFRNGRNVERRGAGKMVLRETVVKETFFDAIHSVLEEKSYSSSVKRISHLMKNKPFTSEERVTKWIDFVLKYETSEHFDLESNNLSIIEHNHLDLFFYLCIISLLNFVVYRKIFKRKSQS
What are the official names of this protein?
Putative UDP-glucuronosyltransferase ugt-50, UDPGT 50.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.