PharMolix/UniProtQA huggingface dataset:
Protein: PA_I78A7
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGCIEGKLSQMSKEVNAKIEPFLKTTPRPIKLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHEKGINSNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEYIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRFEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: HLDE_SHEPC
Sequence: MKVSLPAFEKARVLVVGDVMLDRYWVGPTGRISPEAPVPVVKINQVEDRPGGAANVALNIATLGGQVQLAGLVGQDDTAVALTLGVQTLGVEPQWLSIADKPTITKLRVLSRNQQLIRLDFEEAFDKADSVRLLKQSEALLDSVDVVVLSDYAKGAIDQPRDFIALARSKGVMVLVDPKGSDFGRYHGASLITPNMSEFEAVVGTVTSEADLLEKARGLLKEHHFDAILVTRSEKGMTLVTANAPELHIPTVAREVYDVTGAGDTVISALATSLAAGADLPQACAIANTAAGVVVGKLGTSTVSRIELIEALALHHGESGFGVVSEDQLAYALEQAKLRGERVVMTNGCFDILHAGHVSYLKQAKALGDRLIVAVNDDASVKRLKGEGRPVNQVDRRMAVLAGLASVDWVVPFSEDTPQRIIARLLPDLLVKGGDYKIEDIAGGAEVIAAGGQVQVLGFEDGISTTAIIQNIMANQ
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: HIR3_ARATH
Sequence: MGNLFCCVLVKQSDVAVKERFGKFQKVLNPGLQFVPWVIGDYVAGTLTLRLQQLDVQCETKTKDNVFVTVVASIQYRVLADKASDAFYRLSNPTTQIKAYVFDVIRACVPKLNLDDVFEQKNEIAKSVEEELDKAMTAYGYEILQTLIIDIEPDQQVKRAMNEINAAARMRVAASEKAEAEKIIQIKRAEGEAESKYLSGLGIARQRQAIVDGLRDSVLGFAGNVPGTSAKDVLDMVMMTQYFDTMRDIGATSKSSAVFIPHGPGAVSDVAAQIRNGLLQANNAS
What are the official names of this protein?
Hypersensitive-induced response protein 3, AtHIR3.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: PLAS_DAUCA
Sequence: AEVKLGADDGALVFSPSSFSVAKGEGISFKNNAGFPHNIVFDEDEVPAGVDVSKISQEDYLDGAGESFTVTLTEKGTYKFYCEPHAGAGMKGEVTVT
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
Protein: NHAA_PAEAT
Sequence: MADRPRLPNNSSQTGKVFSRSSYPEYRRILSILRTETVGGALLLAATVVALIWANSPAADGYFALRDVKIGYEPWHLELSLGHWASDGLLAVFFFLAGLELKREFVAGELRKPARAVVPVAAAVGGVVVPALIYVLFNLGTAGETLKGWAIPTATDIAFALAVLAVINTHLPAALRTFLLTLAVVDDLIAIGIIAFFYSTGLQPLMLLAALVPLALFTFLVQKRIRSWYLLLPLALATWGFVHASGIHATVAGVLLGFAVPVLARGKKGEPAEGLAEHLEHKLRPFSAGFAVPVFAFFSAGVALGGLDGMGAALRDPVALGIVAALVVGKAVGVFGTTFLVTKTTRASLDSSIAWIDLFGLALLAGIGFTVSLLIGELSFGAGSAHNDHAKVAILAGSLISALLAAVVLRARNRRYRQVQADEERDDDGDGVPDVFARS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURA_DESVH
Sequence: MSNVVVMGAQWGDEGKGKIVDLLTRESDVIVRFQGGNNAGHTVLVGEKQYILHLIPSGILHEGKKCLIGNGVVLDPEVFCREIDSLRAQGVDMSPARLMISRKTHLIMPYHKVLDQAREAHKCKDAKIGTTGRGIGPCYEDKSARIGVRAADLAMPELLRSKIEAALVEKNALFTGLYGQQPLDADAVFEEVMAHGAKLVPYLADVSSEIHDAWAEGRSVLFEGAQGTHLDIDHGTYPFVTSSNTVSGNAAAGSGVPPTKLDRIIAIVKAYTTRVGAGPFPTELDDATGEYLQQKGHEFGATTGRKRRCGWLDAVVLRESVRLNGPTDIALTKLDVLSGLKEISICTAYIYRGEQVAYPPQEQNGMAHVTPVYETIPGWDDDITGCTTWESLPAPVKAYVLRIEEITGVRISLVSVGPERDQTIRR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STRPB
Sequence: MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLGIASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKEDIELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGNVVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSPKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVTLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_PSEPF
Sequence: MTRTVMCRKYKEQLEGLERPPYPGAKGQDIFEHVSAKAWADWQKHQTLLINEKRLNMMNAEDRKFLQGEMDKYFSGEEYAQAEGYVPPAE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: CADM4_RAT
Sequence: MGRARRFQWPLLLLWAAAAGPGTAQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLVPRSRPAAVLRWYRDRKELKGVSSGQENGKVWSVASTVRFRVDRKDDGGIVICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEALGETLTLPGLVSADNGTYTCEAANKHGHARALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLNGSDGHKRKEEFFI
What is the function of this protein?
Involved in the cell-cell adhesion.  Has calcium- and magnesium-independent cell-cell adhesion activity.  May have tumor-suppressor activity (By similarity).
What are the official names of this protein?
Cell adhesion molecule 4, Immunoglobulin superfamily member 4C, IgSF4C, Nectin-like protein 4, NECL-4.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HOAVI_HOEPD
Sequence: MNKVLAIVLTITVAGFAQTAFADDHAMSPDMKLLAGASNWVNQSGSVAQFVFTPSPTQPQTYEVSGNYINNAQGTGCKGTPYPLSGAYYSGNQIISFSVVWSNASANCQSATGWTGYFDFSGSQAVLKTDWNLAFYSGSTPAIQQGQDDFMQSVATVSESLLTE
What is the function of this protein?
The exact role played by hoefavidin in the host organism is still obscure.  Forms a strong non-covalent complex with biotin and 2-iminobiotin.
What are the official names of this protein?
Hoefavidin.
What is the protein family that this protein belongs to?
Belongs to the avidin/streptavidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_PARUW
Sequence: MNQRTGILLVNLGTPKTPRPKDVYRYLNEFLTDGRVIDLPWLKRQLLVRCIIVPFRYKQSSMLYQKLWTAEGSPLLVHGIAVQTKLQMILGESFQVELAMRYQNPSIEEGLERLKLANVKEIVIFPLFPQYASATTGSVHQEVMKHLQQWQNIPTLTFINSYPDHPGLVGAFCERAKQYDLSIYDYFLFSFHGLPERQIRKGDSTGKCLTENCCQVICSDNAFCYKAQCYRTAKAIASKLRIKLEQYTVCFQSRLGKETWIQPYTSDLLKDCLAKNRKKILVFCPAFVCDCLETTCEVSIEYAEEFKHLGGDTLHLVEGLNSHPVWIEAIKTIIQEHLPHPHSQFSR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNR7_SCHPO
Sequence: METLLSALATLYANTDREQKLQANNYLEEFQKSPAAWQICFSILNQDDSSIEAKLFAAQTLRQKIVYDFHQLPKETHIEFRNSLLQLFLAAKDSPRPLLVSLAVCMAAIALHMTEWHNVIADVFQACSSKDPSGRCVLQFLSVLPEEASDPRKTSLSWEELCIRVDELLRDNGPAVLELLVQYVDAVRASGSPSSADLGLVLTSLISWLREIPLDKVMASPLIELAFRSLDDDLLLEDAVEFLCALFNETKDVDETTDAILMLYPRLLELQPKLIAACDDPETFRALGRLFAEAGEAWVVLIARMPNDFLPLVNCIAQVAANDTELEAIKFTFAFWWDLKQMVELDVYAEARQLFAPIYLELVRIIVRHLHYPRTEDLAINEQMASNEVLFEDRDAEDRFRSFRHEMGDVLKDCCVVAGVSSCLVQISSQLIKVLKIKESGLPYYWQDVEAPLFALRAIGRMVPANEDQVIGSLFQILPQLPENNKVRYAATLFLGRYTEWTAQHSEFLELQLNYISAGFEVANKEVQSAAAQALKHFCYDCREQLVGHLSQLHMFYLNAKTYLAPDPLMEVAQGLAHIVDIQPVANVYQSVHSFLAPSLQSILLAQVKLNPTQAELEALADNIDIVTIFLSLVHPPSPAGELHPIVRLFQDIWPILSRTLDTFSDVLICERISKLLKNFIYTFKEKAIVTLPVITEALIKGFEKTQYGCFLWVSGACVRQFGVPEMDEQTLSAVWSFVGKQCTNMFYYMSNKNPKEIPDVIDDFFRLMMDALLANPQMVLESQMLESLIQAAMMSLQLEQQEPLQTVLNFLQDLLAFALHTPPYSLIEPLPDSLLKSLADLLLKNSQELYIILFNGMVFTFPRDNISDASAVLIPLIRLVFAADPSLCIKYMSNVLDQLPAMTIGQEEREKFLANFSKHCTSSEMPRLRAHLQDWTAMYRRRVLTPRAKLISDD
What are the official names of this protein?
Uncharacterized protein C11G11.07.
Protein: SFSA_TRIV2
Sequence: MIDWLYSYPPLYPGILLKRYKRFFADVQLASGEVVTAHCPNTGPMTGVSTLGSVVQLSKSANPKRKLAYTLELIQVHDNEPTWVGVNTALPNQIVKLALAKYLFPELGSYNHIKSEVVYGVDKKSRVDFFLTGSDTERPIYLEVKNTTWAKGTLALFPDTETTRGQKHLRELMTLLPQTRSVMLYFINRGDCTEFAPGDSTDPIYGKLLREAIALGLEVLPCRFDVTPEGIRYLGLAKLVI
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: YJT5_YEAST
Sequence: MFFICNVGPFRSWKESKIFWKMEDGSPNDIQLILVTATDSSLPSGNSNQDKFCKFGFVCLSTSFERGVESDNGRDWNFCLIIISSWAVLPVPGGPVMYSESDLCSEIAFAKKFITCSYSAVLAGNAPSLLFKLTSSDDFCKSAFVLKKIDCEPNCSFSGDDSGVTSVNCNFFLFKGRGGVAGASSNRFLLIRLVGVIGIADMNVYGTIDENSAAQCSEYSKIVLPENIPLLYK
What are the official names of this protein?
Putative uncharacterized protein YJL195C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACEK_BURMS
Sequence: MNHFPKLLSSQIGFDVAQTILENFDRHYRIFREAAVEAKDLFERADWHGLQRLARERITSYDDRVRECVELLEDEYDAENIDNEVWPQIKLHYIGLLTSHRQPECAETFFNSVCCKILHRAYFNNDFIFVRPAISTEYIENDEPAAKPTYRAYYPGSEGLAATLERIVTNFQLNPPFEDLERDIACIMQAIHDEFGAFDEAVNFQIHVLSSLFYRNKTAYVVGRIINGDRVLPFAVPIRHARAGILALDTVLLRRDQLKIIFSFSHSYFLVDMNVPSAYVQFLRSIMPGKPKAEIYTSVGLQKQGKNLFYRDLLHHLSHSSDRFIVAPGIKGLVMLVFTLPSFPYVFKMIKDHFPPPKDTTREQIMAKYLLVKRHDRLGRMADTLEYSSVALPLARLDDALVRELEKEVPSLIEYEGENLVIKHLYIERRMVPLNLYLQNGSDAEIEHGVREYGNAVKELMQANIFPGDMLYKNFGVTRHGRVVFYDYDEIEYLTDCNVRRVPPPRNDEDEMSGEPWYTVGPHDIFPETYAPFLLGDPRVREHFLAHHADFFDPQLWQDSKDRLLRGELPDFFAYEPALRFCIRYPERFAPGDAADGGKLAAA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_CAMJ8
Sequence: MPKMKSVKSAVKRFKVGKNKIKRGSAFRSHILTKKPAKRMRDLRTAKYVHSTNVKAVEKMLGI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SYL_GRAFK
Sequence: MSYHFNKIEEKWQKYWADNQTFKASNDSEKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIYARFKRHKGFNVLHPQGYDSFGLPAEQYAIQTGQHPAVTTENNIARYREQLDKIGFSFDWSREVRTSEPDYYKWTQWIFIQLFESWYDQEAEKSRAITELEEIFTSEGNSRINAASDDDVEKFSADDWNACSEDEKEQILLKYRLTYLAEAEVNWCPQLGTVLANDEIVNGVSERGGYPVVRKKMTQWSMRISAFSERLLQDLNKIDWTESLKESQRNWIGKSVGAHVDFKIENSKFKIGVFTTRPDTIFGVSFMTLAPEHELVEKITTEDRKEEVQAYIEASAKRSERERMADVKTISGAFTGAYAEHPFTKKPVPIWIGDYVLAGYGTGAVMAVPCGDQRDHDFARHFDLLIPNIFENVDVSQEAYAGKEGTVIANSDFLSGLEYKEALNKVILELEKTGQGYGKTNYRLRDAVFSRQRYWGEPFPVYYVNGLPKMIDEKYLPLKLPEVEKYLPTETGEPPLGNATDWAWDSKNNKVVSNKVLKQSRKLSGQHDEPNSNVTPSAVEGSDDNGIYPLELNTMPGWAGSSWYLFRYMGAGNPDRFVSEEAQKYWENVDLYIGGSEHATGHLLYSRFWTKFLYDRGWLTVEEPFKKLINQGMILGTSAFVYRLEGENVFVSKNQINGNNVQPIHADVSLVNSSDELDIEGFKKWRPEFADAKFLTEDGKYIVGREVEKMSKSKYNVVNPDEICQDYGADTLRMYEMFLGPLEQAKPWNTAGITGVHNFLKKLWKLYYDGEEFFVSDEKASADSLKTFHKTIKKVTEDIEEFSFNTSVSTFMICVNELTAQKCNSREILEPLAVLIAPYAPHIAEELWEKLGNSESVTTAKYPEFEEKYLVESMKNYPVSFNGKMRFTMELSLDMSKEEIEKTVMADERTQKQLDGRTPKKVIVVPGKIVNIVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_CHLPM
Sequence: MKFVDSATVFVQAGDGGRGCVSFRREKYVPKGGPDGGDGGDGGNVWLRTNSHLTTLLDFKYRKKYLAPRGAHGMGSRKAGRKGKDIVIDVPIGTLVRNAESMEVIADLTRPDEEIMIARGGHGGRGNQHFATSTNQAPRRSEPGWKGEELELAMELKLMADVGLVGFPNAGKSTLISVLSAARPKIADYPFTTLVPNLGIVRYEEYKSFVMADIPGIIEGAAEGRGLGLQFLRHIERTKILALLVSADSPDILAEYGTLVAELEKFGHGLIQKPRLLVVTKMDIAPGDFVVPEAPEGVGLIAVSSVAGKGMKELKDELWRQVSLCERQAEPPEDGE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_COXBU
Sequence: MKKLYLKTHGCQMNEYDSAKMADVLKFSHGLELTEDPAVADVFLLNTCSVREKAQTKVFSELGRWRPFKEKRPHVVIGVGGCVASQEGETILKQAPFVDIVFGPQTLHRLPDLLDSVIQKRKSVVDITFPEIEKFDRLPQPRAEGPSAFVSIMEGCSKYCTFCVVPYTRGEEISRPFDDVIAEVASLCEQGVREITLLGQNVNDYRGLMHDGQVADLALLIHYLAAMDNIERIRFTTSHPSAFSENLIDAYAEEPKLANHLHLPVQSGSDRILAAMKRNYTVLEYKSKIRKLRAVRPDISLSSDFIIGFPGETDADFEATMNLIHDMGFDHSFSFIYSPRPGTPAAQLPDDVPMAVKKERLAILQNRINAKAAEISQSMVGTQQRILVTGPSKKYPDQLSGRTENNRVVNFNGDTPLIGQMVTIKIKEARPYSLWGEIC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPX_SHIFL
Sequence: MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIMLNQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALAVLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVTILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSAAVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSDNVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVHIL
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 2, FBPase class 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_MICAN
Sequence: MLPTRDCVRQTPAYTPGEQPQTAGFTKLNTNENPYPPPAEIFAHLQEQLEKVRLYPDPISKELRQTAAELYGIAADQIIAGNGSDDILNIALRTFVNPCESVAFLDLTYSLYETIARVHGANIIEFPTNDKFALEGPIICPEAKLIFLASPNPPLGKHLDRDYLEATCANASGLVLIDEAYVDFSDDNHLDFLSRYDNVIISRTMSKSYSLAGLRVGFGFASRAIIEQMDKVRDSYNLDRIAQTLATAALKHHNYFEQVWQKVRQTRGRLITSLRELGFIVFDSEANFILASPPQISASELYNQLKERQILVRYFKHPRIQNYVRISIGTDGEIDRLLSAIQEIMGTN
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RP25L_MOUSE
Sequence: MEQYRRAGSVELPASSPMPQLPPDTLEMRVRDGSKIRNLLGLALGRLEGGSTRHVVFSGSGRAAGKAVSCAEIVKRRVPGLHQLTKLRFLQTEDSWVPTSPDTGLDPLTVRRHVPAVWVLLSRDPLDPSECGYQPPGAPPGLGSIPSPSCGPRPRRRARDTRS
What is the function of this protein?
May be a component of ribonuclease P or MRP.
What are the official names of this protein?
Ribonuclease P protein subunit p25-like protein, RNase P protein subunit-like p25, Rpp25-like protein.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPAO_SHIFL
Sequence: MLRIKHFDANEKLQILYAKQLCERFSIQTFKNKFTGSESLVTLTSVCGDWVIRIDTLSFLKKKYEVFSGFSTQESLLHLSKCVFIESSSVFSIPELSDKITFRITNEIQYATTGSHLCCFSSSLGIIYFDKMPVLRNQVSLDLLHHLLEFCLGSSNVRLATLKRIRTGDIIIVQKLYNLLLCNQVIIGDYIVNDNNEAKINLSESNGESEHTEVSLALFNYDDINVKVDFILLEKNMTINELKMYVENELFKFPDDIVKHVNIKVNGSLVGHGELVSIEDGYGIEISSWMVKE
What is the function of this protein?
Required for surface presentation of invasion plasmid antigens.  Could play a role in preserving the translocation competence of the Ipa antigens.  Required for invasion and for secretion of the three Ipa proteins.
What are the official names of this protein?
Surface presentation of antigens protein SpaO, Spa33 protein.
What is the protein family that this protein belongs to?
Belongs to the FliN/MopA/SpaO family.
Protein: MQO_PSESM
Sequence: MAHNEAVDVVLVGAGIMSATLAVLLKELDPGLKLEVVELMDSGAAESSNPWNNAGTGHAGLCELNYTPPAADGSIDIKKAVHINTQFEVSKQFWAFLARKGTFGSAKSFINPVPHLSFVQGENGISFLKTRFEAMSKHHAFSSMEYTEDKATLAEWMPLMMSGRAADEKIAATRMLNGTDVNFGALTNQLLNHLSSAPDTQIKYRSRVTGLTRKGAGWTVMVKDVNGGGTREIDAKFVFLGAGGAALPLLQMSGIEESKGFGGFPVSGQWLRCDNPEVVKHHQAKVYSQAAVGSPPMSVPHLDTRVVDGNKSLLFGPYAGFTTKFLKHGSFLDLPLSVRVANIKPMLAVARDNMDLTKYLVSEVMQSMEQRLESLRRFYPEAKAEDWRLEVAGQRVQIIKKDAKKGGVLQFGTELVSAQDGSLAALLGASPGASVTVSIMLELIERCFPEKTRTEWASKLNEIFPAREKILETDAQLYERVSTQNDEALELVEKKSQEQSFA
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: AFB2_ARATH
Sequence: MNYFPDEVIEHVFDFVTSHKDRNAISLVCKSWYKIERYSRQKVFIGNCYAINPERLLRRFPCLKSLTLKGKPHFADFNLVPHEWGGFVLPWIEALARSRVGLEELRLKRMVVTDESLELLSRSFVNFKSLVLVSCEGFTTDGLASIAANCRHLRDLDLQENEIDDHRGQWLSCFPDTCTTLVTLNFACLEGETNLVALERLVARSPNLKSLKLNRAVPLDALARLMACAPQIVDLGVGSYENDPDSESYLKLMAVIKKCTSLRSLSGFLEAAPHCLSAFHPICHNLTSLNLSYAAEIHGSHLIKLIQHCKKLQRLWILDSIGDKGLEVVASTCKELQELRVFPSDLLGGGNTAVTEEGLVAISAGCPKLHSILYFCQQMTNAALVTVAKNCPNFIRFRLCILEPNKPDHVTSQPLDEGFGAIVKACKSLRRLSLSGLLTDQVFLYIGMYANQLEMLSIAFAGDTDKGMLYVLNGCKKMKKLEIRDSPFGDTALLADVSKYETMRSLWMSSCEVTLSGCKRLAEKAPWLNVEIINENDNNRMEENGHEGRQKVDKLYLYRTVVGTRMDAPPFVWIL
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Confers sensitivity to the virulent bacterial pathogen P. syringae (By similarity).  Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription.  Involved in embryogenesis regulation by auxin.
What are the official names of this protein?
Protein AUXIN SIGNALING F-BOX 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYP_LACDB
Sequence: MRQSIFFMPTLKETPADAVAKSHQVMLRGGYIRQVTAGVYSYLPLGYKVLRKTEKIIEEEMANAGVVEMIMPHMLPASMWEESGRLPKYGPEMFRLKDRHGREMLLGPTHEETFTDVVAKSLKSYKQMPLQLYQIQTKFRDENRPRFGLLRGREFVMLDGYSFAASQEQLDKQFDDEKAAYLKIFKRTGVEVRPVIADSGTMGGKNSIEFQAPAAVGEDTIATNASGTYAANLEMAVSVDTFKQEPEELKAMEKVATPGCDSIDKLAEFLQVPATRIVKSVLYIVDEKKKVLVLIRADKEVNEVKLTHLLDCDSLRVAETSDLEELTGAGKGGVGPVNADWADEIVADKTVKGLYNVVVGAGESDAQFINANLDRDFKADRFADLRVANEGEPDPVDHEPLKFTTSIEVGHIFKLGTYYTETMGAKFLDQNGKSQPVIMGSYGIGVTRLLSAVVEQHATENGVAWPKEIAPFGIHIIQMKMKDEIQSKLAEDLEAKFAKYDVLYDDRNERPGVKFNDADLVGAPIRITVGRDAADGIVEVKRPGDDQAQKLAVADLEDFIANELD
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_JANMA
Sequence: MTLTLNHCPAPAKLNLFLHVTGRRADGYHLLQSVFQLIDRGDVLHFATRDDNLIQRTTDLPGVPAESDLVVRAAKLLQTVATEKNPAKNFGADIAVEKKLPMGGGLGGGSSDAATTLLALNHLWQTGLSRAELMALGLQLGADVPFFIFGQNAFAEGIGEALVEVETPDRWFVVIEPGVSVPTPQIFSSTELTRDTKPVKISDFSGAQESFGKNDLQVVAEKLFPPIAEAIQWLGQYGDARMTGSGACVFCPFEQEQQADAVLTTVPPHWKAWKAKAIKHHPLAYLQQS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SGO1_EMENI
Sequence: MARLNESTASSEPIEILKRRFVRQNREIARVNSIQSLRIRSLESEVSNLLSENVSLREQIITLTQELERFEAARTLHDGVYDVKARLDSKLVELGNLITELGSLPRRYSRAVRENGEPAPARQSRESGPKEVDDTDPEPNLGFLDGRLPVIMEDKLYPRRTLTAQEVQELRDSDTDGPNCSGFEDSSISPKQRVEYDEAATGGPAYFIDTNTIVEEIENEHSLPPNLETRRKKKIGPATVNKDQADTRPISLLDSKFTRKCGAKRKFSAEDDESLFESSPSEDDEFQFSRPAQSPKLFSQNEHASADDGSGELRRPIQSPTLSSQNDHSPVKMKPQSERSIAHVHGERRVLEPKSTNTNILSPAKPSIMKDYNQNHDFGYNEKSEKPLPRQGKGAVDGSKNASPKKSSTRTPVFGNDGNKSGNKQKKSGAIKSNTPSLDGIEDSEIATTADMPSTRPSRRRGTVSQPESHKTEGISMPP
What is the function of this protein?
Plays a central role in chromosome cohesion during cell division by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms.
What are the official names of this protein?
Shugoshin.
What is the protein family that this protein belongs to?
Belongs to the shugoshin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere.