PharMolix/UniProtQA huggingface dataset:
Protein: CASP1_VIGUN
Sequence: MSTTVDVPESSNVAKGKAIAVARPGGWKKGLAIMDFILRLGGIAASLGAAATMGTSDQTLPFFTQFFQFEASYDSFTTFQFFVITMALVAGYLVLSLPFSVVAIIRPHAPGPRLFLIILDTVFLTLATASGASAAAIVYLAHNGNQDSNWLAICNQFGDFCAQTSGAVVASFVAVVILVLLVIMSALALRRH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, VuCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: NCAP_I78A8
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVDGKWMRELVLYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGIGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVASGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFDKSTIMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: M10B2_DANRE
Sequence: MSRRNRNNYLSIAAVRTIGLDFIEMLEETNRRSISDRNTLTDIYNTEFRDRDGGVKDPNFSRVLYALRNANKARLSRTGRVYFNTNVRTGLHDQWFRPRRRQQNQANATPGNVSSVTPSSDQGPSCPESGVRARRKLVKYILQRLNTTDRSHFIADKWGVRVSSELYIEDGKIRISVDEAEVYELKLFVENTGQEAVYFTYYTALCWLQYFTLEDSRKVTRNNPLRLEPREKYEVIVRFKSSHVGVYSATLAFEFKKNTQPTTRSFHIVRFIEAEYRSKLAALLGPTEPYKPLRLNISEPENCIIDEGFPPDGYLQNFLVNVLPLGKYIPPPDTTILAELLKEDCSSRIFRGKLKDLQSLLQSPLTFDNYAERFDLLLYLEECQMHVDIKRYNKDSVTLHRDRDKRLMGLNLPGVSENRPSVLRGDHLLLTKSEEVTFSNVTKYKGYVHRVELDQVKLGLSKRFLKDVYIDKMKFRVEFTVNRIPVRLQHRAVHMAVQHNLKDVLFPMASRSLNPVSPPALRLFDRKLEYNFQQYSAVCNIVAGTSKPAPYLVFGPPGTGKTVTIVEAIKQVEKNIPDAYILACAPSNSAADQLCEKLITSEHVDAHKIYRLYASSRNQKDIPKILKDNCNVDEEMIDFPCKEDLMSYKILICTLVTAGRLVTGGFSEDHFTHNFVDEAGHAVESETIISVAGLLNAEKGQLVLAGDPKQLGPILRSPLAINHGLDVSLLERLMTQNDLYKRGDVEFDNRYVSKLIMNYRSHPYILEVPNRLFYDGELKACADEISSNQYCMWEHLPSKGFPVIFHGVPGKDERESNSPSFFNIYEINILVDYLKKLLLTQPKKGISRIFPKDIGIIAPYRKQVEKIKRAIDADKDFQDYMGIDNLKVGSVEEFQGQERKVIMVSTVRSSVKYISLDETFNIGFLKNEKRFNVAVTRAKSLLIMVGNPMILRTDESWGRFIDFCLERGGYTGISITSVERIDDVESRLLALNIQDEETEESPVQRYVDPEFRNDY
What is the function of this protein?
Probable RNA helicase.  Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC).  Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (By similarity).
What are the official names of this protein?
Putative helicase mov-10-B.2.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: Y921_LACDB
Sequence: MQRIWISGYRGYELGTFGDKDPKITVIKYAIKQCLTNLLEEGQLDWVITGANLGVEQWSAEVALELRQDYNLRLAVMLPYLDFGSRWSENNQLKLQNLKNQADFWSATSKGPYQGGRQFREYQQFMFQHTDRALLVYDPEYPGKSKYDYEMIEKYLEKRDDYQLDLVDYYDLEQAARDYEGNQREW
What are the official names of this protein?
UPF0398 protein LBUL_0921.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: TEA1_YEAST
Sequence: MTAPLWPNKNEKNHTVKRALSTDMTSNILSSTNASSNEENSRSSSAANVRSGTGANTLTNGGSTRKRLACTNCRNRRKKCDLGFPCGNCSRLELVCNVNDEDLRKKRYTNKYVKSLESHIAQLETNLKNLVQKIYPDDEQILNRMMVGDVLSALPDSSQVSINYTDQTPSLPIPATRGTFIIENDKVSQPLSSFNQQTEPSTLNSGIFNTQKQNFEESLDDQLLLRRSLTPQGEKKKKPLVKGSLYPEGPVSYKRKHPVKSDSLLPVSSLTAATDPSTFSDGITAGNSVLVNGELKKRISDLKTTVIVRGLNDDNPNSINNDPRILKSLSNFYKWLYPGYFIFVHRESFLYGFFNHSKNNYEDSSYCSVELIYAMCAVGSRLTPDLQEYSEVYYQRSKKTLLQLVFDEQSTARITTVQALFCLAFYELGKGNNQLGWYFSGLAIRVGYDMGFQLDPKVWYVDDNNLQLTQSELEIRSRIYWGCYIADHFICLMLGRTSTLSVSNSTMPESDELPEVNGTEEFRFIGRHVLQISLPLKNLIILSRLVQIFTSKIFIESEDIARKLKYLNTFNSQVYNWRQSLPEFLQWSKTLIENDDVSTDPTISYFWYCYYIVRLTFNKPFIEDSQESETVVIEIIDDLKTLLDNFGKKFGNYTKGNLYQLYSCLLAINCLKKLKEIRSSEQDSWNAQLDFFNHIFYTQLYPAYDLPKKLQEDTELETEQENQMLNQVGNINYTHDFSLSHEIDDLIRELFGVGTPQKL
What is the function of this protein?
TY1 element enhancer binding protein.  Binds to the DNA sequence 5'-TCGGTGGTATTATTCCGA-3'.
What are the official names of this protein?
TY1 enhancer activator.
What are the subcellular locations of this protein?
Nucleus.
Protein: VL1_BPV6
Sequence: YLRHVEEWELSCIMQLCIVDLKPETLAHLHNMDPRILETWNLGFIQPPTNIEDQYRFIKSLATKCPGKEETAEKEDPYAKYKFWDINLTERFSSNWNMYLGRNFLFQIGKRGSKRPAPKTVTFDSSSKKAPKRRRKNA
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and about 55 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  The capsid encapsulates the genomic DNA, but does not bind DNA.  Essential for the initial attachment to the host cell (By similarity).
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion.
Protein: TRPF_PSEP1
Sequence: MSNVRSKICGITRIEDALAAAEAGADAIGFVFYAKSPRAVDVRQARAIIAELPPFVTTVGLFVNASRCELNEILEVVPLDLLQFHGDETPQDCEGYHRPWIKALRVRPGDDLEAACQRYAGARGILLDTYVPGVPGGTGEAFDWSLVPARLGKPIILAGGLSADNVGQAIARVKPYAVDVSGGVEQAKGIKDAAKIEAFMRAVKQA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: NAGS_MOUSE
Sequence: MATAWVATALRSAAAARRLRSPGGPGGSRRLSGSARRRGAKSASPGRRLSTARAHAEDAEGAKGRVQSPAVEEPSWTPLPTPLESPAPPAGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCYHSVDKPFAVMEVDEEVIRCPQAVSRLAFALAFLQRMDMKPLVVLGLPTPTAPSGCLSFWEAKAQLAQSCKVLVDELRHNAATAVPFFGGGSVLSAAEPAPHASYGGIVAVETDLLQWCLESNSIPILCPIGETAARRSVLLDSLEVTASLAKALQPTKIIFLNNSGGLRNNSQKILSNVNLPADLDLVTNAEWLSIKERQQIRLIVDVLSRLPHYSSAVITAASTLLTELFSNKGCGTLFKNAERMLRVRNLDSLDQGRLVNLVNASFGKKLREDYLESLRPRLHSIYVSEGYNAAAILTVEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDPGS
What is the function of this protein?
Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity.
What are the official names of this protein?
N-acetylglutamate synthase, mitochondrial, Amino-acid acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NUSB_BORAP
Sequence: MHEVRVLAFQKIYSIDINQSAMDDIFDIFNIEDKGLDIENESIKSFYSSLVNGTFNNLEHIDSLIRDISWNWSLDRMDKVDLAILRMGVYSLKFQNFENSKRAVIDDAILIAKKYGSKNSCKFINGILDALLKNMEN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: YACG_MANSM
Sequence: MTTKTTDETFTVDCPICKKAVIWSPQSPYRPFCSKRCQLIDLGEWAAEEKAIPCENADFAMDPENNEDWAKH
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: RL6_HAHCH
Sequence: MSRVAKNPVQIPAGVEVKFDGRLVNIKGGKGALSLSVHPSVEVKQEDGALTFGPKEGSNQARALAGTTRALINNMVLGVTQGFERKLELIGVGYRAQAQGKAINLTLGFSHPVVFEIPEGITAETPTQTEIVIRGIDKQKVGQVAAEIRSIRPPEPYKGKGVRYSGEQVRVKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RAD50_ARCFU
Sequence: MILLKELQIKNFRSHSDSKIEFDTGINLIAGRNGAGKSSILEAILVAFYGLKPATLRKNDLVRVNSSGYSLSLTFSLNGDDYTISRKSNGESILTGKEIVEGDSNITEWVERHLCPAHVFTGAIYVRQGEIDSIIRDDESRERIIRQITRIEDYENAWKNLGAVIRMLEREKERLKEFLSQEEQIKRQKEEKKAEIERISEEIKSIESLREKLSEEVRNLESRLKELEEHKSRLESLRKQESSVLQEVRGLEEKLRELEKQLKEVVERIEDLEKKAKEVKELKPKAERYSILEKLLSEINQALRDVEKREGDLTREAAGIQAQLKKAEEDNSKLEEITKRIEELERELERFEKSHRLLETLKPKMDRMQGIKAKLEEKNLTPDKVEKMYDLLSKAKEEEKEITEKLKKLIAKKSSLKTRGAQLKKAVEELKSAERTCPVCGRELDEEHRKNIMAEYTREMKRIAEELAKADEIEKKLKERLEKVEKALEKQETVLKYRQMVDELKALENELSSHDAEKLSAESEEYRKVKERLDGLRGQQKILLSSASRIKELKSSLREIEEALKNVESERGELHRKIREEGFESLEELEREVQSLRPFYNKWLELKDAESRLESELKRREKLEDEISEAIAKLEEANGKAEEIRGQIDELLRIYSEEEHRRLSDEHLRKSKELAGLKSRLETLRESLQSAEKDLKFLEEQLAKMDEYRKKVEVFEKIAIPELTRIREKFRKYRNLVAENSMREVERYASQIFEELTEGKYSGVRLKKTTERGKEKLKVFVVYQGEEREIGFLSGGEIIALGLAFRLALSMFMIRGKIPLLILDEPTPFLDEERRRKLVDITTNYLRKIPQVIIVSHDEELKDAADKVIFVESQGGVSRVRYVEAQ
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
What are the official names of this protein?
DNA double-strand break repair Rad50 ATPase.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
Protein: CH10_DECAR
Sequence: MNIRPLHDRVIVKRVEAERTTASGIVIPDSAGEKPDQGEVLAVGPGKRDDNGKQIALDVKVGDRVLFGKYAGQAVKVDGQEVLVMREEDIMGVLVA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_THEAC
Sequence: MKLEGRRIKGLYLVTEDYSRKNFFNIIEEAIIGGVDIVQYRDKSNPRSVRLDVARKVKQICNRYDILFFIDDDVQLAIEVQADGVHIGKDDMPLPDARRIFDGLIGYSTYGDREMAIFAEKNGADYVAFGPFFHTDTKKDADVYDIHVLEGIHKYIRIPVFVIGGINISNIRTFSGYGIDGVAVVSAIFSDPDPERAARELKAALYNYVLSSA
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: LFTR_BURCJ
Sequence: MVPWLGPDDPFPSIERALGPATGAPGLLAASADLLPSRLIDAYLRGIFPWYSDGQPVLWWSPDPRMILVPAEFKVSPSLRKTLKRVLREPDWEVRVDHDFPGVMRACAQAPRRGQRGTWITAEIIDAYTSLYRSGNAHSIETWHDGRRVGGLYGVSFGRMFFGESMYADVTDASKIALATLVAHLREQGLEMIDCQQNTSHLASLGGREIARKAFVAHVRSAVAEPPIPWQFDKRVLAALTSPAETAAPSGTER
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM14A_PIG
Sequence: MDLIGFGYAALVTFGSILGYKRRGGVPSLIAGLFVGFLAGYGAYRVSLDKRDVKLSLFTAFFLATIMGVRFKRSKKIMPAGLVAGLSLLMILRLVLLLL
What is the function of this protein?
Inhibits apoptosis via negative regulation of the mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
What are the official names of this protein?
Transmembrane protein 14A.
What is the protein family that this protein belongs to?
Belongs to the TMEM14 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.
Protein: LOH3_ARATH
Sequence: MGLLESVKSINWEHESSPVYQDFRVLPLFAVFFPSIRFLLDRFVFEKLAKYLIYGKHRQDMGDDTTERKKKIRKFKESAWKCVYYLSAEILALSVTYNEPWFMNTKYFWVGPGDQTWPDQQTKLKLKLLYMFVAGFYTYSIFALVFWETRRSDFGVSMGHHIATLILIVLSYVCSFSRVGSVVLALHDASDVFLEVGKMSKYSGAERIASFSFILFVLSWIILRLIYYPFWILWSTSYEVVLELDKDKHPIEGPIYYYMFNTLLYCLLVLHIYWWVLMYRMLVKQIQDRGKLSEDVRSDSEGEDEHED
What is the function of this protein?
Essential for plant growth, promotes cell division in root meristems (PubMed:21666002, PubMed:21883234, PubMed:26276842).  Catalyzes the biosynthesis of ceramide sphingolipids with C(16) to C(28) fatty acids, structural membrane lipids involved in membrane trafficking (e. g.  early endosomes) and cell polarity (e. g.  polar auxin transport related proteins); active on a broad substrate spectrum, both regarding chain lengths of fatty acids and the sphingoid base, such as long-chain base (LCB) phytosphingosine (t18:0) (PubMed:21883234, PubMed:26635357, PubMed:21666002, PubMed:26276842).  Mediates resistance to sphinganine-analog mycotoxins (SAMs, e. g.  fumonisin B(1)) by restoring the sphingolipid biosynthesis (PubMed:26276842).  Could salvage the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in ceramides-depleted cells after SAM exposure (By similarity).  Contributes to hypoxic conditions tolerance (e. g.  submergences), especially in the dark, by promoting the formation of very-long-chain (VLC) ceramide species (22:1, 24:1 and 26:1) and of VLC unsaturated ceramides, which are modulating CTR1-mediated ethylene signaling leading to endoplasmic reticulum (ER)-to-nucleus translocation of EIN2 and EIN3 (PubMed:25822663).
What are the official names of this protein?
Ceramide synthase 1 LOH3, CS1, CSII, Protein LONGEVITY ASSURANCE GENE ONE HOMOLOG 3, LAG One Homolog 3, LAG1 homolog 3, LAG1 longevity assurance homolog 3.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CR2AB_BACTK
Sequence: MNSVLNSGRTTICDAYNVAAHDPFSFQHKSLDTVQKEWTEWKKNNHSLYLDPIVGTVASFLLKKVGSLVGKRILSELRNLIFPSGSTNLMQDILRETEKFLNQRLNTDTLARVNAELTGLQANVEEFNRQVDNFLNPNRNAVPLSITSSVNTMQQLFLNRLPQFQMQGYQLLLLPLFAQAANLHLSFIRDVILNADEWGISAATLRTYRDYLKNYTRDYSNYCINTYQSAFKGLNTRLHDMLEFRTYMFLNVFEYVSIWSLFKYQSLLVSSGANLYASGSGPQQTQSFTSQDWPFLYSLFQVNSNYVLNGFSGARLSNTFPNIVGLPGSTTTHALLAARVNYSGGISSGDIGASPFNQNFNCSTFLPPLLTPFVRSWLDSGSDREGVATVTNWQTESFETTLGLRSGAFTARGNSNYFPDYFIRNISGVPLVVRNEDLRRPLHYNEIRNIASPSGTPGGARAYMVSVHNRKNNIHAVHENGSMIHLAPNDYTGFTISPIHATQVNNQTRTFISEKFGNQGDSLRFEQNNTTARYTLRGNGNSYNLYLRVSSIGNSTIRVTINGRVYTATNVNTTTNNDGVNDNGARFSDINIGNVVASSNSDVPLDINVTLNSGTQFDLMNIMLVPTNISPLY
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of lepidopteran (Manduca sexta) larvae.
What are the official names of this protein?
Pesticidal crystal protein Cry2Ab, 71 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIIA(b).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: ISPH_PSEPG
Sequence: MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRNRGAIFVEELDQVPDDVIVIFSAHGVSQAVRQEAAGRGLKVFDATCPLVTKVHIEVAKYSRDGRECILIGHEGHPEVEGTMGQYDASNGGAIYLVEDEEDVANLQVRDPDHLAFVTQTTLSMDDTSRVIDALRARFPNIGGPRKDDICYATQNRQDAVKQLAGESDVVLVVGSPNSSNSNRLRELAERMGTPAYLIDGAEDLQRGWFDQAARIGITAGASAPEVLVRGVIEQLKAWGATGAEELDGREENITFSMPKELRVRSLI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: TM2D2_XENTR
Sequence: MRWPVPPVGYLLLGGQGLLLTFSLISSQNQTSPVTYPDLNLSAAPEPRDPLGPLVLCSYLPEEFVECDDPVDHMGNGTAQQELRYGCKKFGGQAYGDVEHTQVMCRALDGIECDGPRSFLRGNKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDNSNWCTIY
What are the official names of this protein?
TM2 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HBB_CHRRI
Sequence: VHWSAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTQRFFASFGNLSSPTAINGNPMVRAHGKKVLTSFGEAVKNLDNIKNTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFAKDFTPDSQAAWQKLVRVVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta/beta', Beta/beta'-globin, Hemoglobin beta/beta' chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PPNP_SHEB5
Sequence: MSLLEQVSVSKKANIYFDGRVASRSVFFADGSKQTLGVVQPGEYEFSTSQGEIMEVISGRFEVLLPETTTWQEFSEGTQFELAANVSFKIRNTAIAEYCCSYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: PEPB_SALPC
Sequence: MTEAMKITLSTQPADARWGDKATYSINNDGITLHLNGKDDLGLIQRAARKIDGLGIKQVALTGEGWDTERCWAFWAGYKGPKGVRTVMWPDLDDAQRQELDNRLTIIDWVRDTINAPAEELGPEQLAQRAVDLLCSVACDSVTYRITKGEDLREQNYMGLHTVGRGSERPPVLLALDYNPTGDKDAPVYACLVGKGITFDSGGYSIKQSAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIIRYRNGKNVEVMNTDAEGRLVLADGLIDASAQHPQLIIDMATLTGAAKTALGNDYHALFSFDDTLAGRLLTSAAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYREGWLHIDCSATYRKAPVEQWAAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE12_HUMAN
Sequence: MWRLPGARAALRVIRTAVEKLSRAEAGSQTAAGAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRVLSRIATNALKGHAKAAAAKKSRKSRPNASGGAACSGPGPEPAVFCEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNADIGLRLKLHCTPGDGQRFGHSRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADVICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQHEGLATFYRKSKFSLLSQHDISFYEALESDPLHKELLEKLVLYPSAQEKVLQRSSVLQVSVLQSTKDSSKRICVANTHLYWHPKGGYIRLIQMAVALAHIRHVSCDLYPGIPVIFCGDFNSTPSTGMYHFVINGSIPEDHEDWASNGEEERCNMSLTHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK
What is the function of this protein?
Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system.  Degrades triphosphorylated 2-5A to produce AMP and ATP (PubMed:26055709).  Also cleaves 3',5'-phosphodiester bond of oligoadenylates (PubMed:21666256, PubMed:30389976, PubMed:26055709).  Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs).  Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells and Hela cells (PubMed:26055709).
What are the official names of this protein?
2',5'-phosphodiesterase 12, 2'-PDE, 2-PDE, Mitochondrial deadenylase.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: YJ07_YEAST
Sequence: MEAGNRSGTPQHRQLSEIRQDLSSSPDTDAEEFRLLLLLFEQLPSFTLAAKDRSDVRLPDLGNLFLVWATECDSNSFDTDPSLPSFFALSLSNKETISYFTLPISRSIREIYLVNFTNALKNMYFSA
What are the official names of this protein?
Putative uncharacterized protein YJR037W.
Protein: CF047_RAT
Sequence: MFLRRLGGWLPRPWGRKKSTKTDLPAPEPRWVDSSPENSGSDWDSAPETMGDVGPLKTKDSGTRRPPQAAPESSRDTRVYQLGSKRMDSLKKDKAASAIQESARLETGGAVPKLDLDPVDSGGMKNLGVSPQGRLGTTGPEALLEKPGRRQKLLRWLRGEPGAPSHYLQDPEEYLQISTNLTLHLLELLASALLALCSRPLRAILDALGLRGPVGLWLHGLLCFLAALHGLHAVLSLLTAHPLHFACLFGLLQALVLAVSLREPVEDEETADWESEGQGKEAKEQTEGPGRAL
What are the official names of this protein?
Uncharacterized protein C6orf47 homolog.
Protein: MENG_LACPL
Sequence: MANRYLHNVQGLFDTIAPNYDRMNNIISLGTHRHWRKQTMAQIHLASNAHVLDLCCGTGDWTIALAKELQAPGEVIGLDFSAPMLKLAQQKVTQQQVADRVWLRRGNAMHLPFKDNTFDLVTIGFGLRNLPDKAQALTEIYRVLKPGARLVCLETSQPDQPLIKPVWQWYFTKVVPLFGRLFAHQYQEYSYLQETTRHFASYQQLATMFQQAGFQNVHFQRFNFGAAAAHFGTKEAK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.