PharMolix/UniProtQA huggingface dataset:
Protein: PHF8_DANRE
Sequence: MASVPVYCLCRLPYDVTRFMIECDVCQDWFHGSCVGVEEDKAAEIDLYHCPNCQVTHGPSVMRKRRGAVKHADVGLGRDSGRPVKTGSAQFVRELRCRTFPSADEVLLKPTGAQLTVEFLEERSFSVPVLVLRKDGLGMNLPPSSFSVTDVEHYIGTEKEIDVIDVSRQADLKMKLGEFVEYYNSPNRDRVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEESIFERPNVQKYCLMGVKDSYTDFHIDFGGTSVWYHVLRGEKIFYLIRPTAANLSLFERWSSSSNQNELFFGDQVDMCYKCSVKQGNTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIDMQLRAYEIEKRLSTADLFKFPNFETVCWYVGKHLLDTFRGLRENRRHPATYLVHGAKALNNAFRGWTRKESLGEHEQEIPDTIKTQQLVKDLAKEIRLVEDIFQQNIGRSGTPFGGSQGLPSPHPKAQLNTPLTFSQHLSKKRGPKPKEAFGGGGVGPPGAKKKSQKGKEIKTEAGELDLLEIHTKHTLKKFQPGCKVKKSKLELPDDCLDDFEEKINKSKLKLVLTNGKLQGKKGRAGSANGAGSSLQQFQPHMATLSDFDSEDELQIDETPPPRRRPSLPSKKKLAGLPRKLPRAKPCSDPHRIREPGEVDFDIEEDYTTDEEMLTMQGVKGGAGGILDLLKASKQVAGLDSALSEEAPASPSTRDAIQGMLSMANPPSSSSSSSSSSPLSISGGGEMMGLMKEKGGREGWMSGVKKSERKAVFQRPGKRPIKRPARHLSDDESLDEQETLGTCFKDSDYVYPSLESDEEDHVSKSKMKRKRNWDDTPWSPKARVTPTLPKQERPVREGARVASVETGLAAAAAKLAQQEQQKTITKRKYTKKKTPQEKVHSTVAQLQHQPDSAPVSPPLPSEPPVDCIVEERRVEVYSASLLDHEYTAGPGPFSPGGPRGSGAMAPGVFLTSRRPSLSPQNSSSYSPSAPSPGGLVTPTSAGACQGKRPKKGLATAKQRLGKILKIHRNGKLLL
What is the function of this protein?
Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development.  Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1).  Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks.  Involved in cell cycle progression by being required to control G1-S transition.  Acts as a coactivator of rDNA transcription, by activating polymerase I (pol I) mediated transcription of rRNA genes.  Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate (By similarity).  Required for brain development, probably by regulating expression of neuron-specific genes.
What are the official names of this protein?
Histone lysine demethylase PHF8, PHD finger protein 8, zPHF8, [histone H3]-dimethyl-L-lysine(36) demethylase PHF8, [histone H3]-dimethyl-L-lysine(9) demethylase PHF8.
What is the protein family that this protein belongs to?
Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Recruited to H3K4me3 sites on chromatin during interphase. Dissociates from chromatin when cells enter mitosis (By similarity).
Protein: LIP10_CANAL
Sequence: MKTLLIFLAFLSSIFASLIGLTPPSKDSFYSPPVGFATAKPGDILKIRNTPSAPSSLYLPIVVKNAWQLLIRSEDSFGNPNAFVATLIQPLNANPSKLVSYQSWEDASHIDCSPSYGMQFKSPATTVTTQIDMTLIVPLLQNGYYVIIPDYEGPKSTFTVGRQSGKATLNSIRAALQTGAFSGIKKTAKVALWGYSGGSLATGWAISLQSKYAPELKENLIGAAVGGFATNITAVAEAVDGTVFSGFIPLALNGLANEYPDFKKRLYGEVKLSARSTMEKGSQNCLAASLVGYPMSQYFTGQNRAFEKGWGLLQDEVFNKTIEDNLLLKLDKTYLPQVPVLIYHGTIDEIIPIKDANAQYQIWCDRGIQSLEFAEDLSAGHLAETFTGAPAALSWIDARFSGKPAVNGCQRTIRSSNVLYPGISITIRIYFEGISKTIFGVNLGSGVNADKSISNKFFAYIRKYI
What are the official names of this protein?
Lipase 10.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: RLME_STRMK
Sequence: MATRSKSSQRWLKEHFSDPFVKKAQAEGMRSRAAYKLEELLERDRLLKPHMVVVDLGAAPGGWSQQVRRQIGDTGRVLALDILDMPPLAGVEFLHGDFREEAVLSQFEAMLGDQPVDLVLSDMAPNKSGVGAVDQPRMMHLAELALDFADNHLKTGGAFLIKLFQGEGFDDYVRDMRRRYDKVSIRKPEASRKRSPEVYALGQGKRAHMK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_CAMHC
Sequence: MISLNHYLIVAALMFVIGLVGVMKRQNLIMLFFSTEILLNAANVALVAISSFYNDIGGQIFAMFIIAIAASEMAVGLGLLILWYKKRHSIEIDSLSTMRDE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATP1_ORYSI
Sequence: MVIARGLLRSNASSSSSQAINLLKYVTSTGSLQGHTQNLCDASTRHFSSVPSPQSNSTEENGFKGHGMLAPFTAGWQSTDVHPLVIERSEGSYVYDIDGKKYLDSLAGLWCTALGGSEPRLAKAATEQLHKLPFYHSFWNRTTKPSLDLAKELLSMFTAREMGKVFFTNSGSEANDSQVKLVWYYNNALGRPDKKKFIARSKSYHGSTLISASLSGLPALHQKFDLPAPFVLHTDCPHYWRFHLPGETEEEFATRLANNLEELILKEGPETIAAFIAEPVMGAGGVIPPPKTYFEKVQAIVKKYDILFIADEVITAFGRLGTMFGSDMYNIKPDLVSMAKALSSAYVPIGAIMVSPEISDVIHSQSNKLGSFAHGFTYSGHPVACAVAIEALKIYQERNIPDHVKQISPRFQEGVKAFAGSPIVGEIRGVGLILGTEFADNKSPNDPFPAEWGVGAIFGAECQKRGMLVRVAGDNIMMSPPLIMTPDEVEELVSIYGDALKATEERVAELKSKKNN
What is the function of this protein?
Transaminase that degrades gamma-amino butyric acid (GABA) and uses pyruvate as amino-group acceptor, but not 2-oxoglutarate.
What are the official names of this protein?
Gamma-aminobutyrate transaminase 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GPDA_HELAH
Sequence: MEISVFGGGAWGRALAFAFGEKNEVKIISRRDLNEPLKKLNDALISKGSAPIEQVDLETGLKASLYVVAISVQHLREWFQNASLPKNAKVLIASKGIEVLNKAFVSEIAKDFIEPNHLCFLAGPSFAAEIIQGLPCALVIHSNNQALALEFANKTPSFIRAYAQQDIIGGEIAGAYKNVIAIAGGVCDGLKLGNSAKASLLSRGLVEMQRFGAFFGGKTETFLGLSGAGDLFLTANSILSRNYRVGLGLAQNKPLEVVLEELGEVAEGVKTTNAIVEIAKKYGIYTPIASELALLLKGKSVLESMNDLIRRA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_PSESM
Sequence: MNPLRRKRLLIILAVLGGVGLALTLALSALKENINLFYTPSQIANGQAPLGTRIRAGGMVEKGSLQRSTDSLDVRFVVTDFNKSVTIAYRGILPDLFREGQGIVALGKLDAQGVVVADEVLAKHDEKYMPPEVSKALRESGQATPAPASMPARQADR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SRA_SALPA
Sequence: MKSNRQARHILGLDYRISNQRKVVTEGDTSSVVNNPTGRKRRADSQK
What is the function of this protein?
Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein.
What are the official names of this protein?
Stationary-phase-induced ribosome-associated protein, SRA, 30S ribosomal protein S22.
What is the protein family that this protein belongs to?
Belongs to the SRA family.
Protein: GLRX_MIMIV
Sequence: MSYYMSPIVQKITGADPGTFVLFYVPECPYCQRALSTLRERNLPFKGYNINNISGNMPRLLQVLTTYSNLTGFNPYHTTKPIIFINGKFIGGMDDLAKYLDVQFTQ
What are the official names of this protein?
Probable glutaredoxin.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Virion.
Protein: LAEA_ASPNA
Sequence: MFEISRLLHQPITMASPNRNNYSYQGIESYDSGRSRQNSDAMDIHVITAQEPPREPPDNNDPYDGHGGPAGTSHYSKPPNRWLFYEENGRTYHGYRRGVYPLPCDEQEQDRLDIFHKLFTVARMSESLIYAPHPPNGRFLDLGCGTGIWAIDVAHKYPNAFVAGVDLAPIQPPNHPDNCEFYAPFDFEAPWTLGENSWDLIHLQMGCGSVLGWQNLYKRILRHLQPGAWFEQVEIDFEPRCDDRSLNGLALREWYQYLKQATQDTMRPIAHSSRDTIRHLEEAGFTQIDHQMVGLPLNPWHRDEHEQKVARWYNLAISESIETLSLAPFSRIFHWDLDRIRQITAEVKSQAFNKEIHAYNILHIYQARKPGGPSL
What is the function of this protein?
Methyltransferase that performs automethylation (By similarity).  No other methyl-accepting substrate has been identified yet (By similarity).  Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:26566947).  Controls the expression of the citric acid, demethylkotanin, orlandin, asperrubrol, tensidol B, atromentin and JBIR8 gene clusters (PubMed:26566947).  Represses also the expression of genes related to the production of BMS-192548 and aspernigrin A (PubMed:26566947).
What are the official names of this protein?
Secondary metabolism regulator laeA, Methyltransferase laeA, Velvet complex subunit laeA.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRR1L_MOUSE
Sequence: MAAAALEPWSAVAPRRRKRAAGRRPRPGEGPRAEPEADGEAVLRRLREAEEDLRISDFCSSALETITECLRKQLEQLQPLTEALGRLHLGSSLPSASQEPLASSASHVKCVCYGLGTFASCPTARIQLAFMLLFLEKCQVPRSHCWVYDPLFSQTEVSVLTSLGVTVLSENEEGKRSVQGQPTVFYMPHCGTALYNNLLWSNWSADALSRVLIIGNSFRGLEERLLARILQENYPYIAKVSDRIAGPGF
What is the function of this protein?
Plays a role in the regulation of heme biosynthesis and in the regulation of the expression of core clock genes.
What are the official names of this protein?
SRR1-like protein, SRR1 domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the SRR1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Also found in intracellular organelles.
Protein: TSAD_YERPS
Sequence: MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLSAKDIDAVAYTAGPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDDAAGEAFDKTAKLLGLDYPGGPMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFEDAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLRSNLNSELSVSVRPRWPLSELPKV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_BRUA1
Sequence: MIQKNWQELIKPNKVDFITHGSRTHATVVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAVQIDGVLHEFSSIPGVREDVTDIVLNIKEIAIRMEGEGPKRMVVRKEGPGVVTAGDIQTVGDVEILNPEHVICTLDEGAEIRMEFTVNTGKGYVPADRNRAEDAPIGLIPVDSLYSPVRKVSYKIENTREGQVLDYDKLTLNIETNGSVTGEDAVAYAARILQDQLSIFVNFEEPQKEAPQEQVAELAFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLASMGLHLGMEIPAWPPENIEDLAKRYEDQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: HLDE_GEOUR
Sequence: MERKEIESLFTRAREIRALVIGDLMLDEYLWGKAERISPEAPVQVVDVTREDLRLGGAGNVVNNLVALGCQVAVCSVIGGDENGSHLRHAFTGKGVDLTGVFEDPLRLTSKKTRVIAANQQIVRIDRESRDEISLEFEEKVLDFIAAEAARFNVILVSDYLKGVLTPRVLEAVCAAGRRLGIPVVVDPKGSDYGKYRGATILTPNRKEAETASRMSIRTEEGLTRAAETLLAGLELDALLITRSEEGMSLFMQDGRTVHIPTVAREVYDVTGAGDTVLSVLSVGLACGLEFGEAARVANVAAGIAVGKLGTSTVSPGEIIAEIGHAHPDSDAKIKNLDALAAIVKAEKTRGKRLVFTNGCFDLLHVGHVKYLQKARTFGDLLVVGLNSDASVRRLKGAERPLIGEAERAHILAALDCVDFVVIFDEDTPLRLIETLQPQVLVKGGDYTPERVVGKEVVESYGGRVELVTFVDGKSTTNIIEKIRTGSIKE
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: SPTSB_XENTR
Sequence: MDVKHIKDYLSWLYYQYLLITCSYVLEPWEQSIFNTLLLTIIAMVIYSSYIFIPIHVRLAVEFFSGIFGGQHESTVALMS
What is the function of this protein?
Stimulates the activity of serine palmitoyltransferase (SPT).  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference (By similarity).
What are the official names of this protein?
Serine palmitoyltransferase small subunit B, Protein ADMP, Small subunit of serine palmitoyltransferase B, ssSPTb.
What is the protein family that this protein belongs to?
Belongs to the SPTSS family. SPTSSB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ERI3_BOVIN
Sequence: MATASPAADGGRGRPWEGGLVSWPPAPPLTIPWTWMGPSWGQHPGHWGFPALTEPSASPAASLGIFEVRRVLDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHSFGASMAAMMSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF
What are the official names of this protein?
ERI1 exoribonuclease 3, Prion interactor 1, Prion protein-interacting protein.
Protein: IGHA1_GORGO
Sequence: ASPTSPKVFPLSLCSTQPDGDVVVACLVQGFFPQEPLSVTWSESGQGVTARNFPPSQDASGDLYTTSSQLTLPATQCPDGKSVTCHVNHYTNPSQDVTVPCRVPSTPPTPSPSTPPTPSPPCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGVTFTWTPSSGKSAVEGPPERDLCGCYSVSSVLPGCAEPWNHGKTFTCTAAYPESKTPLTATLSKSGNMFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMAEVDGTCY
What is the function of this protein?
Ig alpha is the major immunoglobulin class in body secretions.  It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system (By similarity).
What are the official names of this protein?
Ig alpha-1 chain C region.
Protein: HEMOT_DROME
Sequence: MDCFKVFEVVFQSEINPLLLIPAVATIALTLCCYCYHGYQWIRDRRTARIEEQQAQLPLPLSRISITPGCSMVATTKLTHSRNSVDIY
What is the function of this protein?
Negatively regulates early endosome maturation by binding to and repressing the activity of 14-3-3zeta which prevents the 14-3-3zeta-mediated activation of phosphoinositide 3-kinase Pi3K68D.  This, in turn, inhibits the Pi3K68D-mediated conversion of phosphatidylinositol to phosphatidylinositol-3-phosphate and prevents progression of early endosomes through the maturation process which regulates subsequent steps of phagocytic processing.
What are the official names of this protein?
Hemotin.
What are the subcellular locations of this protein?
Early endosome membrane; Single-pass membrane protein.
Protein: HIS8_GEOMG
Sequence: MIPLRQNIASMKGYIPGYQPPDIASWIKLNTNENPYPPSPEVVKAILEELGPDGAALRIYPSASSQKLREVAGELYGFDPSWIIMANGSDEVLNNLIRAFAAEGEEIGYVHPSYSYYGTLAEVQGARVRTFGLTGDFRIAGFPERYEGKVFFLTTPNAPLGPSFPLEYIDELARRCAGMLVLDETYAEFAESNALELVRRHENVVVTRTLSKSYSLAGMRIGLAIARPEVIAALDKIRDHYNLDRLAQAACVAALRDQAYLSECCRRIRETREWFTTELRSIGYDVIPSQGNYLFATPPDRDGKRVYDGLYARKVLVRHFSDPLLAHGMRISIGTREEMEQTLAALKEIG
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: PTLA_STAAM
Sequence: MNREEVQLLGFEIVAFAGDARSKFLEALTAAQAGDFAKADALIEEGNNCIAEAHRAQTSLLAKEAQGDDIAYSVTMMHGQDHLMTTILLKDLMKHLLEFYKRG
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport.
What are the official names of this protein?
PTS system lactose-specific EIIA component, EIIA-Lac, EIII-Lac, Lactose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSP41_BOTPI
Sequence: VVGGDECDINEHPFLAFLYSHGYFCGLTLINQEWVLTAAHCDRRFMRIYL
What is the function of this protein?
Snake venom serine protease that interferes with the hemostatic system of the prey.  It almost completely degrades both Aalpha (FGA) and Bbeta (FGB) chains of fibrinogen.  It presents a higher ability to degrade fibrin clots than BpirSP27.  It hydrolyzes chromogenic substrates S-2238 (used for testing thrombin activity), S-2222 (factor Xa), S-2266 (glandular kallikrein and factor XIa), and S-2302 (plasma kallikrein, factor XIa and XIIa).  It shows a decrease in the clotting time of human plasma in the presence of increasing doses of the enzyme.  Its minimum coagulant dose (MCD) is 20 ug.  It promotes platelet aggregation with a maximum of aggregation of 20%, regardless of the concentration increase or the presence of calcium.  It also shows 40% inhibition of the hemolytic activity promoted by the complement pathways and possess only a minor role in the induction of edema and pain in rat.
What are the official names of this protein?
Thrombin-like enzyme BpirSP41, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PANC_PSEF5
Sequence: MNTVKTVRELRAAVARARSEGKRIGFVPTMGNLHSGHAALVAKAAQRVDFVVASIFVNPLQFGAGEDLDKYPRTLAADQEKLLEAGCHLLFAPTVEEMYPDGMAGQTRVSVPQLSEGLCGASRPGHFEGVATVVSKLFNMVQPDLAVFGQKDYQQLAVIRALVHDLNMPIQIIGEPTVRAADGLALSSRNGYLSEEQRAIAPVLYRSLSQIAQAIRNGERDYPKLVAEQQQQLEAAGLRRDYLEIRQAQNLRPATAQDRELVILVAAYLGATRLIDNLHLDLDTPA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPC1_ORYSJ
Sequence: MEGSLVQSAIAPTIYRRSGTARFRVRARATMMRTMPTRTLTLGGFQGLRQTNFLDSRSVIKRDFGSIVASQISRPRGLGSRGVVRAMFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGIAAKVLKSMGINLKDARVEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGSEHLLLGLLREGEGVAARVLESLGADPNNIRTQVIRMVGESTEAVGAGVGGGSSGQKMPTLEEYGTNLTKLAEEGKLDPVVGRQDQIERVTQILGRRTKNNPCLIGEPGVGKTAIAEGLAQRISNGDVPETIEGKKVITLDMGLLVAGTKYRGEFEERLKKLMEEIKQNDDIILFIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHIEKDPALERRFQPVKVPEPTVDETIQILRGLRERYELHHKLRYTDDSLIAAAQLSYQYISDRFLPDKAIDLIDEAGSRVRLRHAQLPDEAKELDKELRQVTKDKNEAVRGQDFEKAGELRDREMELKAQITAIIDKSKEMVKAETESGEVGPLVTEADIQHIVSSWTGIPVEKVSSDESDRLLKMEETLHTRIIGQDEAVKAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKSELAKALAAYYFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGYTEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMMLQILEDGRLTDSKGRTVDFKNTLLIMTSNVGSSVIEKGGRKIGFDLDYDEKDTSYNRIKSLVTEELKQYFRPEFLNRLDEMIVFRQLTKLEVKEIADIMLKEVFDRLKAKDIDLQVTEKFRDRVVDEGYNPSYGARPLRRAIMRLLEDSLAEKMLAGEVKEGDSAIVDVDSEGKVIVLNGGSGVPEPLAPALSV
What is the function of this protein?
Molecular chaperone that may interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast.
What are the official names of this protein?
Chaperone protein ClpC1, chloroplastic, ATP-dependent Clp protease ATP-binding subunit ClpC homolog 1, Casein lytic proteinase C1.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRH_CAMC1
Sequence: MSKRKRVLVKFSGEALAGENGFGIDTAVLKFIASEIKELIENDIEVGIVIGGGNIVRGVSAAKDGIIKRTSGDHMGMLATVINSIAMREALERSGLEVRVQSAIKMEAICETFIVGRAQRHLEKGRVVIFAAGTGNPFFTTDTAATLRAIEIGSDMIIKATKVDGVYDKDPKKFKDAKLLKSLNYEKAMSDDIKVMDDTAIALAKDNALPILVCNMFKAGNLLKIINEEEAALYSVVK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR8K1_HUMAN
Sequence: MNHVVKHNHTAVTKVTEFILMGITDNPGLQAPLFGLFLIIYLVTVIGNLGMVILTYLDSKLHTPMYFFLRHLSITDLGYSTVIAPKMLVNFIVHKNTISYNWYATQLAFFEIFIISELFILSAMAYDRYVAICKPLLYVIIMAEKVLWVLVIVPYLYSTFVSLFLTIKLFKLSFCGSNIISYFYCDCIPLMSILCSDTNELELIILIFSGCNLLFSLSIVLISYMFILVAILRMNSRKGRYKAFSTCSSHLTVVIMFYGTLLFIYLQPKSSHTLAIDKMASVFYTLLIPMLNPLIYSLRNKEVKDALKRTLTNRFKIPI
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 8K1, Olfactory receptor OR11-182.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CNG20_ARATH
Sequence: MASHNENDDIPMLPISDPSSRTRARAFTSRSRSVSLSNPTSSIEGFDTSTVVLGYTGPLRTQRRPPLVQMSGPLTSTRKHEPLFLPHPSSDSVGVSSQPERYPSFAALEHKNSSEDEFVLKHANLLRSGQLGMCNDPYCTTCPSYYNRKAAQIPTSRVSALFDSTFHNALYDDAKGWARRFASSVNRYLPGIMNPHAKEVQTWTKFFALSCLLAIFIDPLFFFLIKVQEQNKCIMIDWPMTKAFVAVRSVTDVIFTMNILLQFRLAYVARESTVVGAGQLVSHPKKIALHYLKGKFFLDLFIVMPLPQILILWIIPAHLGASGANYAKNLLRAAVLFQYIPKLYRLLPFLAGQTPTGFIFESAWANFVINLLTFMLAGHVVGSCWYLFGLQRVNQCLRNACGNFGRECQDLIDCGNGNSSVLVRATWKDNASANACFQEDGFPYGIYLKAVNLTNHSNLFTRYSYSLFWGFQQISTLAGNQVPSYFLGEVFFTMGIIGLGLLLFALLIGNMQNFLQALGKRNLEMTLRRRDVEQWMSHRRLPDGIRRRVREAERFNWAATRGVNEELLFENMPDDLQRDIRRHLFKFLKKVRIFSLMDEPILDAIRERLKQRTYIGSSTVLHRGGLVEKMVFIVRGEMESIGEDGSVLPLYEGDVCGEELLTWCLERSSVNPDGTRIRMPSKGLLSSRNVRCVTNVEAFSLSVADLEDVTSLFSRFLRSHRVQGAIRYDSPYWRLRAARQIQVAWRYRRRRLHRLCTPQSSYSL
What is the function of this protein?
Probable cyclic nucleotide-gated ion channel.
What are the official names of this protein?
Probable cyclic nucleotide-gated ion channel 20, chloroplastic, Cyclic nucleotide-binding transporter 1.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GUAA_STAAE
Sequence: MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.