PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_VEREI
Sequence: MAAPDSRLPNIALAGPTAAGKTAAALALAAALGRRQAVEIISVDSALVYRGMDIGSAKPTPAERAAVPHHLIDIRDPLQAYSAAEFVQDARRLIGEIRARGALPLLVGGTMLYFKALFDGLDAMPAADPAVRARLNARAAEQGWPALHTELARVDPVTAARLAPGDSQRIQRALEVWQISGQPLSSFHAIEKGAAGAYGACACALFSLEPQDRAWLHERIARRFDAMLAAGFIAEVQALRARGDLHPDLPAMRCVGYRQVWEALDWQARHAGGPPLHGAPLHARGMDAVRERGVAATRQLAKRQITWLRSMPQRHTTACDQPQAVAQLVQAVLQRLEQHAP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: Y1818_BACFR
Sequence: MEWLYSLFIEHSALQAVVVLSLISAIGLGLGKIHVCGISLGVTFVFFAGILAGHFGLSIDPQMLNYAESFGLIIFVYALGLQVGPGFFSSFRKGGVTLNMLAIAVVILGTFLAVVCSYTTGVSLPNMVGILCGATTNTPALGAAQQTLKQMGLESSTPALGCAVAYPLGVIGVILAVLLIRKLLVRREDLEVQEKDDANKTYIAAFQVHNPAIFNKSIKDIAHMSYPKFVISRLWRDGNVSIPTSEKIIKEGDRLLVVTSEKDALALTVLFGEQENTDWNKEDIDWNAIDSQLISQRIVVTRPELNGKKLGALRLRNHYGINISRVYRSGVQLLATPELTLQLGDRLTVVGEAAAIQNVEKVLGNAIKSLKEPNLVAVFVGIILGLALGAVPFSIPGISTPVRLGLAGGPIIVGILIGTFGPRLHMITYTTRSANLMLRALGLSLYLACLGLDAGAHFFDTVFRPEGLLWIGLGFGLTLVPTVLVGFFAFKIMKIDFGSVSGMLCGSMANPMALNYANDTIPGDNPSVAYATVYPLSMFLRVIIAQVLLMFLL
What are the official names of this protein?
Uncharacterized transporter BF1818.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RHAL_RHILO
Sequence: MSETIISAEVVEKNNAARKPDLERDYASLGERLDRRGIAIDAIRAKVEKFAVAIPSWGVGTGGTRFARFPGAGEPRDIFDKIEDCAVISQLTQATPTVSLHIPWDKADPNRLKQAASRFGLGFDAMNSNTFSDARDQKLSYKFGSLSHADAGTRRQAVEHNLECIEIGKTLGSKALTVWIGDGSNFPGQVNFARAFERYLDAMKAVYAGLPADWKLFTEHKMYEPAFYSTVVQDWGTNYLIAKELGDRAFCLVDLGHHAPNVNIEMIVSRLIQFKKLGGFHFNDSKYGDDDLDAGSIDPYRLFLVFNELVDAELSGAEGFDPAHMLDQSHNVTDPIESLMLSAVEVQRAYAQALLVDRKALEGFQDGNDALMATQTLKAAYRTDVEPILAMARLKTGGAIDPVATYRAAGYRAKVAAERPAVTGGSGGIV
What are the official names of this protein?
Probable sugar isomerase mlr5709.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
Protein: PQQE_PSEAE
Sequence: MRNSGSSCSESVGPPLWLLAELTYRCPLQCPYCSNPLEFAREGAELSTAEWIEVFRQARELGAAQLGFSGGEPLLRQDLAELIEAGRGLGFYTNLITSGIGLDEARLARFAEAGLDHVQISFQAADEEVNNLLAGSRKAFAQKLAMARAVKAHGYPMVLNFVTHRHNIDNIERIIQLCIELEADYVELATCQFYGWAALNRAGLLPTRAQLERAERITAEYRQRLAAEGNPCKLIFVTPDYYEERPKACMGGWASVFLDITPDGTALPCHSARQLPVQFPNVREHSLRHIWYESFGFNRYRGDAWMPEPCRSCEEKERDHGGCRCQAFLLTGDADATDPVCAKSARHDLILAARRQAEEAPLGLDALTWRNQRASRLICKA
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: PYRE_ACIB3
Sequence: MTTPVSFHPQAFIELALSRGVLKFGEFTLKSGRVSPYFFNAGLLNDGEALSLLAQGYADKLTQCENVDVIFGPAYKGIPFVAATAVALSQTHNKSVPWGFNRKEAKDHGEGGILVGAAVEGKKVWIIDDVITAGTAIREVVTILKNAGATIAGVLVALDRQERGQGELSAIQEVQKELEIPVHALITMKDLMDYLEAKGEKEALANMQAYREKYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RS12_STAAB
Sequence: MPTINQLVRKPRQSKIKKSDSPALNKGFNSKKKKFTDLNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNNIEINAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ERC6L_HUMAN
Sequence: MEASRRFPEAEALSPEQAAHYLRYVKEAKEATKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQGDDEFTDVCNSGLLLYRELHNQLFEHQKEGIAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDASLVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQMLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNNLQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKPYFLRRTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRKFVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGTFSAQDGNEGEDSPDVDHIDQVTDDTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNRHFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYFSKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYTCDLSVKEELDVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVFPSSTKKKCPKLNKPQPQPSPLLSTHHTQEEDISSKMASVVIDDLPKEGEKQDLSSIKVNVTTLQDGKGTGSADSIATLPKGFGSVEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQEDPLESFNYVLSKSTKADIGPNLDQLKDDEILRHCNPWPIISITNESQNAESNVSIIEIADDLSASHSALQDAQASEAKLEEEPSASSPQYACDFNLFLEDSADNRQNFSSQSLEHVEKENSLCGSAPNSRAGFVHSKTCLSWEFSEKDDEPEEVVVKAKIRSKARRIVSDGEDEDDSFKDTSSINPFNTSLFQFSSVKQFDASTPKNDISPPGRFFSSQIPSSVNKSMNSRRSLASRRSLINMVLDHVEDMEERLDDSSEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLMTSKPSALAQETSLGAPEPLSGEQLVGSPQDKAAEATNDYETLVKRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN
What is the function of this protein?
DNA helicase that acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase (PubMed:17218258, PubMed:23973328).  Functions as ATP-dependent DNA translocase (PubMed:23973328, PubMed:28977671).  Can promote Holliday junction branch migration (in vitro) (PubMed:23973328).
What are the official names of this protein?
DNA excision repair protein ERCC-6-like, ATP-dependent helicase ERCC6-like, PLK1-interacting checkpoint helicase, Tumor antigen BJ-HCC-15.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Chromosome, centromere. Chromosome, centromere, kinetochore. Chromosome. Note=Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase. In prometaphase cells, it mostly concentrates in between kinetochores. In metaphase, it localizes to numerous thin threads that stretch between sister kinetochores of the aligned chromosomes and are composed of catenated centromeric DNA. Evolution from inner centromeres to thin threads takes place in response to tension. Resolution of thin threads requires topoisomerase 2-alpha (TOP2A) after anaphase onset.
Protein: LPXC_COXB1
Sequence: MIKQRTLKNVVRATGVGVHTGEKVYLTLRPAPPNTGIIFCRTDLDPVVQIPARVNYIGDTSLSTCLTKGDVRIATVEHLLSALAGVGVDNLYIDLTSPELPIMDGSAGPFVFLIQSAGIEEQNAPKEFIRIKQRVKIEEADKSVMVEPYNGFKISFGIDFDHPLFNEHNQNATLDFSSTSYVKEVSRARTFGFLSDYEFIRKNNLALGASLDNALVLDEYKILNQDGLRYPDEFVKHKILDVIGDLYLLGRSLIGSFSGVKSGHTLNSQLLKKLLATKSAWEIVTFKDPSELPFAYTPVAMTA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: GATA_LACP3
Sequence: MDYFKTSIDQLHEQLRSGKVTSSQLVDETLAGINQLDAEVDAFLALNADGAKEKAAAVDAAGIADDQPLAGVPIAIKDNIVTKGVVTTAASKILANFNPIYDATVIQKLDAAGAINVGKTNMDEFAMGSSTENSAFKTTKNAWDHTRVPGGSSGGSAAAVAAGEVIAALGSDTGGSIRQPAAFNGIVGVKPTYGRVSRWGLIAFSSSLDQIGTLTRHVKDAAQLLNVIAGHDERDSTTADTPVPDFTAKIGQDIKGMKIALPKEYLGKGVDPAVADKIKAAAKQFEDMGATVTEVSLPHTQYAVPSYYIIASSEASSNLQRFDGIRYGFRAKDVKNIEDVYVRSRSEGFGPEVKRRIMLGTFSLSAGFYDAYFKKAGQVRTLITRDFEDVFKDYDLIIGPTTPTVAFKIGEKVTDPVTMYMNDILTIPVNLAGLPAASVPAGFVDGMPVGLQLIGKHFDESTIFQVAAAFEAQNDYLAQIPGGK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: TRUA_BURMS
Sequence: MRIALGIQYDGAAFCGWQSQPHGKTVQDALERSLAEFAQTSLHTTVAGRTDTGVHGLGQVVHFDTDLDRADFSWVRGTNAFLPPTVAVQWAKPMPDTFHARFAAFERTYYYALYVHPVRSPMLAGRAGWVHTPLDVDAMREAAAHLVGEHDFSAFRSSECQAKSPVKHLYQIGIRPDGDFIHFRFRANAFLHHMVRNLMGCLVAVGRGRYPSSWLAEVLESRDRDCAAPTFMPEGLYLAHVGYPAEFAVPPAQLGSVPWSSVWADLDGRT
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TPS7_HEDCO
Sequence: MSVSLSFAASATFGFRGGLGGFSRPAAAIKQWRCLPRIQCHSAEQSQSPLRRSGNYQPSIWTHDRIQSLTLSHTADEDDHGERIKLLKCQTNKLMEEKKGEVGEQLQLIDHLQQLGVAYHFKDEIKDTLRGFYASFEDISLQFKDNLHASALLFRLLRENGFSVSEDIFKKFKDDQKGQFEDRLQSQAEGLLSLYEASYLEKDGEELLHEAREFTTKHLKNLLEEEGSLKPGLIREQVAYALELPLNRRFQRLHTKWFIGAWQRDPTMDPALLLLAKLDFNALQNMYKRELNEVSRWWTDLGLPQKLPFFRDRLTENYLWAVVFAFEPDSWAFREMDTKTNCFITMIDDVYDVYGTLDELELFTDIMERWDVNAIDKLPEYMKICFLAVFNTVNDAGYEVMRDKGVNIIPYLKRAWAELCKMYMREARWYHTGYTPTLDEYLDGAWISISGALILSTAYCMGKDLTKEDLDKFSTYPSIVQPSCMLLRLHDDFGTSTEELARGDVQKAVQCCMHERKVPEAVAREHIKQVMEAKWRVLNGNRVAASSFEEYFQNVAINLPRAAQFFYGKGDGYANADGETQKQVMSLLIEPVQ
What is the function of this protein?
Monoterpene synthase involved in the biosynthesis of volatile compounds present in floral scent (PubMed:25056927).  Mediates the conversion of (2E)-geranyl diphosphate (GPP) into sabinene and sub-products such as alpha-thujene, alpha-pinene, beta-pinene, myrcene, alpha-phellandrene, alpha-terpinene, beta-phellandrene, gamma-terpinene and terpinolene (PubMed:25056927).  Unable to use farnesyl diphosphate (FPP) as substrate (PubMed:25056927).
What are the official names of this protein?
Monoterpene synthase 7, chloroplastic, HcTPS7, Alpha-pinene synthase, Alpha-terpinene synthase, Beta-phellandrene synthase, Beta-pinene synthase, Gamma-terpinene synthase, Myrcene synthase, Sabinene synthase, Terpinolene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PELB_EMENI
Sequence: MRLHAPILSLLAAAASTSAAGVTGSAEGFAKGVTGGGSATPVYPSTTAELVSYLGDSSARVIVLTKTFDFTGTEGTTTETGCAPWGTASACQVAINKNDWCTNYQPNAPSVSVTYDNAGVLGITVKSNKSLVGEGSSGVIKGKGLRIVSGASNVIIQNIAITDLNPKYVWGGDAITLDNADMVWIDHVTTARIGRQHLVLGTSASNRVTVSNSYFNGVTSYSATCDGYHYWGIYLTGSNDMVTLKGNYIYHMSGRSPKVGGNTLLHAVNNYWYDSSGHAFEIDSGGYVLAEGNVFQNIPTVIEGTVGGQLFTSPDSSTNAICSTYLGHTCQVNGFGSSGTFKQADTAFLVNFQGKNIASASAYTVAQSSVPSNAGQGKL
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.
What are the official names of this protein?
Pectin lyase B, PLB.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_ECO45
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL3_BRUA1
Sequence: MRSGVIAQKLGMTRVYNDAGEHVPVTVLRMENCHVVAQRTVEKNGYTAVQLGVGMAKVKNTSKAMRGHFAKAEVEPKAKLAEFRVSPDNLLEVGVEITAEHFVAGQKVDVTGTSIGKGFAGVMKRHNFGGHRASHGNSITHRSHGSTGQRQDPGKVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRGLILVRGAVPGSKGAWILVRDAVKASLPENAPKPAGLRAGAKAEAAATEGGE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: H2B3_VOLCA
Sequence: MAPKKEEKPASQAAEAPEVKAEAKPKAVKAPKKKEKKAPAKKVAKEPSAGGEDGDKKSKKKAKVAKSETYKLYIYKVLKQVHPDTGISSKAMSIMNSFINDIFEKVATEASKLSRYNKKPTVTSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.3, H2B-III.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CTLA4_HUMAN
Sequence: MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
What is the function of this protein?
Inhibitory receptor acting as a major negative regulator of T-cell responses.  The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
What are the official names of this protein?
Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4.
Protein: YQHA_SALPB
Sequence: MERFLENVMYASRWLLAPVYFGLSLALIALALKFFQEILHVLPNVFALAEADLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISAGKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y249_PYRAB
Sequence: MIDELIERMKKGDRRATARLITLVENDEEKAREIIRKIYPLTGNAYIVGITGPPGAGKSTLLDKLIKEARKEGLIVGVIAIDPTSPFTGGALLGDRIRMQRHSTDPGVFIRSMATRGSLGGLAKATNDAIKVLDAYGCDVIFVETVGVGQVEVDIVKTADTVVLVTVPGLGDDVQTIKAGLMEIADIFVINKADKEGADATYFELNLALDLESDKWRELGWRPPVVETVATMNKGIKELWDKIKEHREFLERSGRLKEKRRKRIEEEIKTIVSGIIAGKVEASIKRGEFEEIIRRVSQKDIDPYSAADMILKEIIGGGLSVQEN
What is the function of this protein?
May have GTPase activity.  May also bind and hydrolyze ATP.  May function as chaperone (By similarity).
What are the official names of this protein?
Putative GTPase PYRAB02490.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.
Protein: AT233_ANGAN
Sequence: MSGNKDSDGGWKTFIWNSEKKELLGRTGCSWFKILLFYVIFYGCLAAVFVGTIQALLLTLSNYKPTHQDRVAPPGLSHTPCPEKAEITFNKHELETYMKYTKGMKEFLELYDETAQLDQLKYEDCGENPGGYKNRGDLESDIGVRKACRFKRSWLKDCSGLEDRTFGFKDGKPCVIVKLNRIVNFRPKPPNSNESIPEDAKAKVRPNVIPIYCTNKKEEDAGKLQEVKYFGIGDGFPLQYYPYYGKLLHPQYLQPLVAIQFTNLTMNTELRIECRIYGENIGYSEKDRYQGRFDIKITVNDS
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-233, Sodium/potassium-dependent ATPase subunit beta-233.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: ERCC3_SCHPO
Sequence: MSLKRKNNAREGTPDEDLEEYSDYSDVDNYGEEDDDSYKPAPRIRINNNKTKAQTTTNSNEARQSGISAMFGQNDFSNLLGLKLDHTARPLWINPIDGRIILEAFSPLAEQAIDFLVTISEPVSRPAFIHEYRITAYSLYAAVSVGLKTEDIIAVLDRLSKTPIPPSIVDFIRACTVSYGKVKLVLKKNRYFIESGDASVLRLLLRDPVIGPLRIDYSTQSSKQKSSKPSNEDNVEDKKDITNDSSKETAEKSSSDELFSAVVGLQEEEDDEDAVHLFEIKHSSVETIKKRCAEIDYPLLEEYDFRNDNINPDLPIDLKPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQWRQQFLQWSNIKPDHIAVFTADHKERFHSEAGVVVSTYSMVANTRNRSYDSQKMMDFLTGREWGFILLDEVHVVPAAMFRRVVTTIAAHTKLGLTATLVREDDKIDDLNFLIGPKMYEANWMDLAQKGHIAKVQCAEVWCAMTTEFYNEYLRENSRKRMLLYIMNPKKFQACQFLIDYHEKRGDKIIVFSDNVYALRAYAIKLGKYFIYGGTPQQERMRILENFQYNELVNTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSSKRQAFLIDQGYAFKVITNLKGMENLPNLAYASKAERLELLQEVLLQNEEAADLDDGEDTSFGSRSLSRAPAKAKRSSGSLSTLAGADNMAYVEYNKSANKQLKKDSKEHHALFRKHLYTKRR
What is the function of this protein?
ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  The ATPase activity of XPB/ptr8, but not its helicase activity, is required for DNA opening.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  The ATP-dependent helicase activity of XPB/ptr8 is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription (By similarity).  Plays a role in mRNA export (PubMed:17212653).
What are the official names of this protein?
General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, DNA repair helicase ptr8, Poly(A)+ RNA transport protein 8, RNA polymerase II transcription factor B subunit ercc3, TFB subunit ercc3.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD25/XPB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPPP1_BACCZ
Sequence: MSDIIIAFILGIVEGLAEFLPISSTGHLILVGHLLGFEGERAKTFEIVIQLGAILAIAILYHKRLVSLCNIKPLLRKEKKFNAFHVFLGVFPAVVAGLLLHDVIKTYLFQPYTVVIGLVAGAILMILAEVKKQEATACSLDDLTYRQALTIGFFQCLAVYPGFSRAGSTISGGLLAKVNYKTASEFSFLIALPVMVGATSLDLLKSWKYLSVDDIPMFAVGFITSFIVAMLAVVTFLKLLEKIGLKPFAYYRILLAILFTLFVLL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 1, Bacitracin resistance protein 1, Undecaprenyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIG_PSEF5
Sequence: MSNVRSDKPFVLAGRTYQSRLLVGTGKYRDMEETRLAIEASGAEIVTVAVRRTNIGQNPGEPNLLDILPPDRYTILPNTAGCYDAVEAVRTCRLARELLDGHNLVKLEVLADQKTLFPNVLETLKAAEVLVKEGFDVMVYTSDDPIIARQLAEMGCIAVMPLAGLIGTGLGICNPYNLQIILEEAKVPVLVDAGVGTASDATIAMELGCEAVLMNSAIAHAQQPVMMAEAMKHAIVAGRLAYLAGRMPKKLYASASSPLDGLIK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUBPL_DICDI
Sequence: MFKKLITTPFFSPNKQFITFQLESGKRNYFSNNKIQLHGGSGHRQPQVTKVAIEGIKNIIAVSSAKGGVGKSTCAVNIALGLSSHNLSVGLLDVDVFGPSIPLMMDLKNHEKPFTNELNQMIPLQNYGIKCMSMGFLVNEDDPIIWRGPMVGSALEKLLRQTDWGHLDVLVCDLPPGTGDAILTMCQRVPLTGAVIVSTPQDVALADVVRGVNMFKKVEVPILGLVENMSYFNCPHCNESTHIFGNEGAKNTAKKMGINFLGDVPIHLQIRETSDSGKPITVTQPDSPQAKNYKDISKEIIKQLEIINNDENKDNKEPNIIIT
What is the function of this protein?
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I).  May deliver of one or more Fe-S clusters to complex I subunits (By similarity).
What are the official names of this protein?
Iron-sulfur protein NUBPL, Nucleotide-binding protein-like.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CISD2_DROME
Sequence: MEPISHLVKSSLPNYLSSLPVPDSIGGWFKLSFKDWLALIPPTVVVAGLGYTAYLAYCPAARASCAAKNSGRCNNHIRKNEPKVVDMIDVEDIAEKAAFCRCWKTKNWPYCDGSHGEHNKQTGDNVGPIVIKK
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RPPH_BRUMB
Sequence: MSEHKGPTGAMVDPESLPYRPCVGLMVLNKAGLVWAGRRIVIPGDEMDGATQLWQMPQGGIDKGEDPAQAALRELYEETGMTSVSLLEEASDWINYDLPPHLVGLALKGKYRGQTQKWFAYRFEGDESEIAINPPPGGHTAEFDCWEWKPMADLPNLIVPFKRKVYEQVVATFRHLAA
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.