PharMolix/UniProtQA huggingface dataset:
Protein: APT_SALSV
Sequence: MTATAQQLEFLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIELLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPRKLPRETIAETYELEYGTDQLEIHVDAIKPGDNVLVVDDLLATGGTIEATVKLIRRLGGKVTDAAFIINLFDLGGEQRLEKQGITCYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB28_SYNP2
Sequence: MAVIQFSQGVNEPEVPGIRLTRSPDGSTGTAVFSFEDPAALAQESTDEITGMYLIDEEGEIVTREVKAKFYDGKPRIIEARLVMRSTAEWDRFMRFMERYAAENGLEFTKA
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PTG3C_STAA9
Sequence: MRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAIQGEALQHYLPFIQNGGVQNVAKLMTAAGSIIFENLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNVTDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDVHLGYTFSGGFIDYVLLGVLPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQSQAVTASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPFNGKIQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIICBA component, EIICBA-Glc, EII-Glc, EIICBA-Glc 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTXS_PSEAE
Sequence: MNGSVLPSRGRVTINQVAEAAGVSKASVSRYIGGDRQLLADATARRIERAIDQLDYRPNQMARGLKRGRTRLIGMLVADILNPYSVAVMHGVETACREHGYSLVVCNTDRDDEQERHHLAALQSYNVEGLIVNTLGHHPGELRALHRELPMVLVDRQLAELDTDLVGLDNADAVEQALDHLQHRGFRDILLVTEPLDGTSSRIERVQAFNASIGRRPALKGQVLQTDDFFRDGLRAFLSASGPGPKALFTCNGVATLCATRQLRDLGCRLFDEVGLLALDELDWYPLVGSGITALAQPTDEIGRTAFERLLARLEGDREPARRVTFPAQLIVRGSTHPRG
What is the function of this protein?
In addition, in pathogenic strains, PtxS modulates PtxR activity in response to 2-ketogluconate (PubMed:9645431, PubMed:22844393, PubMed:24019239).  In the presence of PtxR, which also binds to the kgu and gad promoter regions, PtxS and PtxR form a tight complex, creating a DNA-loop that prevents RNA polymerase promoter access and expression of the glucose metabolism genes (PubMed:10931350, PubMed:22844393, PubMed:24019239).  Binding of the 2-ketogluconate effector to PtxS causes PtxS/PtxR complex dissociation and leads to the dissolution of the repression DNA-loop, facilitating the entry of the RNA polymerase and enabling the transcription of the genes (PubMed:22844393, PubMed:24019239).  Also plays an important role in the regulation of the expression of the virulence factor exotoxin A (toxA) (PubMed:9645431, PubMed:22844393).  PtxS does not bind directly to the toxA promoter but negatively regulates the production of exotoxin A by binding to PtxR and interfering with its positive regulator activity (PubMed:9645431, PubMed:22844393).  In the presence of 2-ketogluconate, PtxS is released and PtxR can recruit RNA polymerase (PubMed:22844393).
What are the official names of this protein?
HTH-type transcriptional regulator PtxS.
Protein: TRHO_SHEON
Sequence: MSNVVVCALYKFVSLPHFESLREPLLSMMEQAEIKGTLLLASEGINGTVAGNQAAIDALLIWLNQQNGLENITYKLSFDDEMPFYRTKVKLKKEIVTMGVEGIDPLKVVGTYVKPKDWNALISDPEVVLVDTRNDYEVQIGTFKNAINPVTETFREFPEYVKQNLDPAKHKKVAMFCTGGIRCEKSTAYLKEQGFEEVYHLEGGILKYLEEVNKAESLWEGECFVFDNRVAVDHDLKKGQYDQCNACRMPITEAEKLTPDYVQGVSCPHCIDKISEEQRKRFVERERQVNLAKSRNEAHIGSDVNHVIEARRQKKEALRKQSAEKNKAKQANA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: EFTU1_SHEFN
Sequence: MAKAKFERNKPHVNVGTIGHVDHGKTTLTAAISAVLSKTYGGEVKNFAQIDNAPEERERGITINTSHIEYDTPIRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLSRQVGVPFIIVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDLPVIQGSALKALEGQPEWEAKILELAEALDTYIPEPARDIDKPFLLPIEDVFSISGRGTVVTGRVERGIVRVSDEVEIVGVRPTTKTTCTGVEMFRKLLDEGRAGENCGVLLRGTKRDDVERGQVLAKPGSINPHTTFESEVYVLSKEEGGRHTPFFKGYRPQFFFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIYPIAMDDGLRFAIREGGRTVGAGVVAKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKHN1_MOUSE
Sequence: MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARKLAGLFGTEARPDGDTAANRIFHYIPGTDIPGPEHHPENLEQPFLSVFKKGWRRTPVRNLGKVVHYSKVRLRFQHSQDISDCYLELFPSHLYFQAHGSEGLTFQGLLPLTELNICPTDGSREHAFQITGPLPAPLLVLCHSEAELSHWLYHLEKQMALLGLQRCHSAPPQGSLGDKPPWTQLRRAYGCGSMSGAICASRVKLQHLPSQEQWDRLLVLYPASLAIFSEEPEGLSFKGELPLSAIHINLEEKEKEIRSFLIEGHLINTIRVVCASYEDYSQWLLCLRTVSRRDGAHLPPGPESFPGLQKPTQLVGRGRGSLSSNGRSSWKLECPVFPTSQSLPESSVPTTIGFPAPPVPNQTDSNCVSTGQKKMKPSDSSPSPRGRAQREVSGSTVPLPLPLDLTKMSALNLDSGPEAQDHSLDIPHSPLYADPYTPPATSRHKITDIQGLDEFLCAIQTSPGPDLSSPFPPVSVSVPVSESSSGISSSPGPLGSHLLTKKGALQPRASQRHRGSFKSRGPQPSDFPQLVTPAREGKPSSLPPPPDEEAPIWNKTSSPSHPKWPQPRKPAVEGGFIQWI
What is the function of this protein?
Controls the stability of the leptin mRNA harboring an AU-rich element (ARE) in its 3' UTR, in cooperation with the RNA stabilizer ELAVL1.  Decreases the stability of the leptin mRNA by antagonizing the function of ELAVL1 by inducing its atypical recruitment from the nucleus to the cytosol (PubMed:27616329).  Binds to cardiolipin (CL), phosphatidic acid (PA), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidylserine (PS) (By similarity).
What are the official names of this protein?
Probable pleckstrin homology domain-containing family N member 1, PH domain-containing family N member 1, Cardiolipin and phosphatidic acid-binding protein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Mitochondrion membrane. Mitochondrion. Note=Interaction with C1QBP and phosphorylation is essential for its mitochondrial localization. Localizes on the microtubule in the form of small granules.
Protein: Y2474_RHIME
Sequence: MLSLRPNCECCDRDLPPDSGDAMICTFECTFCAGCAETKLGGTCPNCGGELVRRPVRPASMLKKYPASTARVLKPQGCAPERAA
What are the official names of this protein?
Uncharacterized protein R02474.
Protein: BIOB_COXB2
Sequence: MKGRNWNQASVAKLFELPFFELLYKAYETHRSHFDVRDMELCTLSSIKTGTCPEDCAYCPQSGHYKTDVEREKLINLEAVLEQAKVAKENGARRFCMGAAWRSPPKRELPKVLEMIKSVKALGLETCVTLGMLDQEQALQLKEAGLDFYNHNLDTSPEFYKKIITTRTYQDRMETLKNVRNAGINVCCGGILGMGESRADRIQLLLELYQLPEPPTSIPINQLIPIKGTPLENTKAIDPFEFIKTIAITRLLFPTSVIRLSAGREAMSDELQAWCFMAGANSIFYGDKLLTAKNPGQNRDVNLLKKLGLKVPVLTEEYACY
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: MOAA_BRUME
Sequence: MRNVQAQPLVSPTEPMIDPFGRAVTYLRVSVTDRCDFRCTYCMAEHMTFLPKKDLLTLEELDRLCSVFIEKGVRKLRLTGGEPLVRKNIMHLIGNLSRHLKSGALDELTLTTNGSQLARFAGELADCGVRRINVSLDTLNPEKFRTITRWGDLSRVLEGIDAAQKAGIHVKINAVALKDFNDAEIPELIRWAHGRGMDVTLIETMPMGEIEFDRTDQYLPLSQVRADLASQFTLADIPYRTGGPARYVTISETGGRLGFITPMTYNFCESCNRVRLTCTGMLYMCLGQNDDADLRKALRESESDEHLSQAIDEAISRKPKGHDFIIDREHNRPSVARHMSLTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RS14Z_STAAR
Sequence: MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: TLPA_BACSU
Sequence: MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQSAVASLDVQMTQSAKENVQILDHIIDDKISTTEKSLAYFSDWATAEKFQDKKKTELKQEFKQFIQMNDNVAAVFSSGKDGDFTRYPYADMPSDFNALERDWYKEAMANKGKTIVTEPYESISSGKMVVTIARQTVDGSGVVAIDMKIDDLVTTAKGINIGKEGYAFILSQNKKVIAYSGEKAGTELKGDWVDKLYKDKSGDFEYTYKGKKKKMAFATSQTTGWKISGTMYANEIHDAASRVLIMASIVLAIAIGAGMTAIYFVIRSITKPLRRIVASAEKISEGDLTETIEINSKDELGVLSESFNHMAHSLRSLIHGIKDSVEHVASSSEELTASADQTSRATEHITMAIEQFSNGSESQSEKIETTTEQINEMNDGLAELARAAAVITETSADSTEVSSKGETLVQKTAGQMNTIDHSVKAAEQVVKGLEIKSKDITNILRVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIESLISEIVKEIHTSLNVLQSVNKEVETGLVMTDETKQSFKHISQMTNQIASELQNMNATVEELSAGAQEISAASNDITAISKESSDGIQDIAASAEEQLASMEEISSSALTLERMSEELRDLTKQFKVDK
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.  All amino acids serve as attractants in B. subtilis, they appear to cause an increase in the turnover methyl groups, leading to methylation of an unidentified acceptor, while repellents have been shown to cause a decrease in methyl group turnover.  The methyl groups are added by a methyltransferase and removed by a methylesterase.
What are the official names of this protein?
Methyl-accepting chemotaxis protein TlpA.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H669_METJA
Sequence: MEVEYMNFNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFAIPLIELVNENNGIEAIILTPTRELAIQVADEIESLKGNKNLKIAKIYGGKAIYPQIKALKNANIVVGTPGRILDHINRGTLNLKNVKYFILDEADEMLNMGFIKDVEKILNACNKDKRILLFSATMPREILNLAKKYMGDYSFIKAKINANIEQSYVEVNENERFEALCRLLKNKEFYGLVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKIRILIATDVMSRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGKKGKAISIINRREYKKLRYIERAMKLKIKKLKFG
What are the official names of this protein?
Probable ATP-dependent RNA helicase MJ0669.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: LAP2_TRITO
Sequence: MKSQLLSLAVAVSTISQGVVGQEPFGWPFKPMVTQDDLQNKIKLKDIMAGIEKLQSFSDAHPEKNRVFGGNGHKDTVEWIYNELKATGYYNVKKQEQVHLWSHAEAALSANGKDLKASAMSYSPPANKIMAELVVAKNNGCNATDYPENTQGKIVLIQRGVCSFGEKSSQAGDAKAIGAVVYNNVPGSLAGTLGGLDKRHVPTAGLSQEDGKNLASLVASGKVDVTMNVVSLFENRTTWNVIAETKGGDHNNVVMLGAHSDSVDAGPGINDNGSGSIGIMTVAKALTNFKLNNAVRFAWWTAEEFGLLGSTFYVDSLDDRELHKVKLYLNFDMIGSPNFANQIYDGDGSAYNMTGPAGSAEIEYLFEKFFDDQGLPHQPTAFTGRSDYSAFIKRNVPAGGLFTGAEVVKTPEQVKLFGGEAGVAYDKNYHGKGDTVANINKGAIFLNTRAIAYSVAEYARSLKGFPTRPKTGKRAVNPQYAKMPGGGCGHHTVFM
What is the function of this protein?
Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides and contributes to pathogenicity.
What are the official names of this protein?
Leucine aminopeptidase 2, Leucyl aminopeptidase 2, LAP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28A subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GMHA1_CAMJE
Sequence: MINLVEKEWQEHQKIVQASEILKGQIAKVGELLCECLKKGGKILICGNGGSAADAQHFAAELSGRYKKERKALAGIALTTDTSALSAIGNDYGFEFVFSRQVEALGNEKDVLIGISTSGKSPNVLEALKKAKELNMLCLGLSGKGGGMMNKLCDHNLVVPSDDTARIQEMHILIIHTLCQIIDESF
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase 1, Sedoheptulose 7-phosphate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB_SPHAL
Sequence: MTNDDLTITDPKMRAQGVNVFYGDKQAINNVSIDVGTDLVTAFIGPSGCGKSTFLRSLNRMNDTVASAKVTGKIELDGEDIYAPSMDVVQLRARVGMVFQKPNPFPKSIYDNVGYGPRIHGLAPSKADLDVVVERALVRAGLWDEVKDRLNESGTALSGGQQQRLCIARAIAVDPEVILMDEPCSALDPIATAKIEELIHELRGKYAIVIVTHNMQQAARVSQRTAFFHLGTLVEYGKTTDIFTNPKQERTKDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL33_AGRFC
Sequence: MAKATTIKIKLLSTADTGTFYVTTKNSRTFTDKMTKTKYDPVVRKHVEFKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RSMG_YERPA
Sequence: MLKKLDSLLTVAGITLPDQQKHQLIGYVELLDKWNKAYNLTSVRDPQQMLVRHILDSIVVNPHLQGSRFIDVGTGPGLPGIPLAIVRPDAHFTLLDSLGKRVRFLRQVQHELGLNNIEPVQSRVEAFTSEPPFDGVISRAFASLQDMLSWCHHLPAKPEGRFYALKGVRPDDELAVLPEDIVLESVIKLDVPELDGERHLIILKSN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDC3_XENLA
Sequence: MAADWLGSIVSINCGNTLGVYQGCVSAVDRINQTISLSQPFHNGVKCLVPEVTFRAGDISELKILEIPSESLKYTSDQLNDHSTGFGYLPTRQQNGTGKQKQTVAHNSAQNIPGQEEGKASEPSSTSPQPCSKSFVDRHNEAVNQPKNFRRRHNSLGSSSSRYPNQVTPKKSGTKNGQLKARDDECFGDELEEIPDTDFDFEGNLALFDKAAVFEEIDTHERRGGGGTRSRGTPNERPPTYRHDENILESEPIVYRKIVVPQSGGQEYCTDSGLVVPSISYVLHKKLLCVAEKHGLSVERRLEMSGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANYDVDIILFLPNFVKMLEPVTNELNLFCQTQGKQVSSVKDLPECPVDLVINCLDCNENAFLCDQPWYRAAVDWANHNRAPVLNIDPPVGDHVQGIHAKWSLELGLPLALGEQAGRIYLCDIGIPQKVFREVGISYHSPFGCKFVIPLHSM
What is the function of this protein?
Binds single-stranded RNA.  Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity).
What are the official names of this protein?
Enhancer of mRNA-decapping protein 3, YjeF domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDC3 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Processing bodies (PB).
Protein: BXRA_AGRCO
Sequence: MKLLVVLCCFFAVYSLAAAQGGQEEFQIKVRICGRHLARTLADLCPNVEYEDVMKRSGARSPALYGTVGWPWARPGAARGKRAGVADDCCVNSCTMDVLLSYC
What are the official names of this protein?
Bombyxin-related peptide A, ABRP.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VEXIN_MOUSE
Sequence: MHQIYSCSDENIEVFTTVIPSKVSSSSRRRVKSSHHLLAKNVVIESDLYPPPRPLELLPQRCERRDTGDRRWLQTGRLQTARPPGAHPTKTPSRPVGISEPKTSNLCGNRAYGKSLIPPVARISVKAPAGAEVAAKGSEHGAVLGRGSRHLKKIAEEYPALPQGAEASLPLTGSTSCGVPGILRKMWTRHKKKSEYVGATNSAFEAD
What is the function of this protein?
Required for neurogenesis in the neural plate and retina.  Strongly cooperates with neural bHLH factors to promote neurogenesis (PubMed:29518376).
What are the official names of this protein?
Vexin.
What is the protein family that this protein belongs to?
Belongs to the vexin family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Note=Nuclear localization is essential for its function in neurogenesis.
Protein: 3BHS4_MOUSE
Sequence: MPGWSCLVTGAGGFLGQRIVRMLVQEEELQEIRALFRTFGRKQEEELSKLQTKTKVTVLKGDILDAQCLKRACQGMSAVIHTAAAIDPLGAASRQTILDVNLKGTQLLLDACVEANVPTFIYSSSVLVAGPNSYKEIILNAHEEEHHESTWSNPYPYSKKMAEKAVLAANGSILKNGGTLHTCALRLSFIYGEECQVTSTTVKTALKNNSIIKKNATFSIANPVYVGNAAWAHILAARSLQDPKKSPSIQGQFYYITDDTPHQSYDDLKCTLSKEWGLRLDTSWSLPLPLLYWLAFLLETVSFLLRPVYNYRPPFNRLLITVLNSVFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVMQHREIGNKKSQ
What is the function of this protein?
Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids.  Catalyzes the conversion of dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR.  Does not function as an isomerase.
What are the official names of this protein?
NADPH-dependent 3-keto-steroid reductase Hsd3b4, 3 beta-hydroxysteroid dehydrogenase type 4, 3 beta-hydroxysteroid dehydrogenase type IV, 3 beta-HSD IV, Dihydrotestosterone 3-ketoreductase.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: IBMP_CAMVC
Sequence: MENIEKLLMQEKILMLELDLVRAKISLARANGSSQQGDLPLHRETPVKEEAVHSALATFTPTQVKAIPEQTAPGKESTNPLMASILPKDMNPVQTGIRLAVPGDFLRPHQGIPIPQKSELSSIVAPLRAESGIHHPHINYYVVYNGPHAGIYDDWGCTKAATNGVPGVAYKKFATITEARAAADAYTTSQQTDRLNFIPKGEAQLKPKSFAKALTSPPKQKAHWLTLGTKRPSSDPAPKEISFAPEITMDDFLYLYDLGRKFDGEGDDTMFTTDNEKISLFNFRKNADPQMVREAYAAGLIKTIYPSNNLQEIKYLPKKVKDAVKRFRTNCIKNTEKDIFLKIRSTIPVWTIQGLLHKPRQVIEIGVSKKVVPTESKAMESKIQIEDLTELAVKTGEQFIQSLLRLNDKKKIFVNMVEHDTLVYSKNIKDTVSEDQRAIETFQQRVISGNLLGFHCPAICHFIKRTVEKEGGTYKCHHCDKGKAIVQDASADSGPKDGPPPTRSIVEKEDVPTTSSKQVD
What is the function of this protein?
Enhances the ribosomal termination-reinitiation event leading to the translation of major open reading frames on the polycistronic viral RNAs.
What are the official names of this protein?
Transactivator/viroplasmin protein, Tav, Inclusion body matrix protein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae viroplasmin family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in cytoplasmic occlusion bodies.
Protein: ISCA_YERPP
Sequence: MSISISDSAAQRVSAFLNHRGKGLGLRLGVRTSGCSGMAYVLEFVDEINDDDIVFEDKGVKVIIDGKSMVYLDGTELDFVKEGLNEGFKFNNPNVSNECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: TREF_ECO45
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARNWLKTVNQFYLEQHKLIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAMTA_XENLA
Sequence: MSSDKIFAEGESCKSAWHDATAGYDETDTHLEIMGKPVMERWETPYMHSLATVAASKGGRVLEIGFGMAIAATKLEEYNIEEHWIIECNDGVFKRLQEWATKQPHKIVPLKGLWEEVVPTLPDGHFDGILYDTYPLSEETWHTHQFNFIKSHAYRLLKPGGVLTYCNLTSWGELLKTKYNDIEKMFKETQTPQLVDAGFKSENISTTVMDLVPPEDCRYYSFKKMITPTITKV
What are the official names of this protein?
Guanidinoacetate N-methyltransferase A.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
Protein: ATPF_PARBR
Sequence: MASRLAKSAICAARVRPVLSSRTIPAAATTLTSTRSVSNVPTEDPKTKAQSIIDALPGNSLVSKTAILSAGAGLSIAAISNELYVFSEETVAAFCLLSVFAGVAKMAGPMYKEWAETQIQKQKDILNGARANHTNAVKQRIENVKQLSGVVDITKALFEVSKETARLEAQAYELEQRTALAAEAKKVLDSWVQYEGQVKVRQQRELAQTVISKVQKELENPKVIQQILQQSVTDVERIFAAKPQ
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity).
What are the official names of this protein?
ATP synthase subunit 4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase B chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: ACDB2_METJA
Sequence: MFDDIPVSVGPMNEGERVRGPDMYVELAGPKSYGFELVKVVNKAEDKVEIIGKDIDEMEEGSRNPFAIIVEVSGSNLEEDLEGVLERRIHEFLNYIEGVMHLNQRDQVWIRINKDSFNKGLRLKHIGKVVQRLFKAEFPFIEKCDVTIITDPEKVKEELEKAREIYNKRDEKTKALHEEDVDVFYGCVMCQSFAPTHVCVITPDRPALCGGINYLDARAAAKIDPNGPIFEIPKGECLDEKLGIYSGVNEVVRERSQGTVEEVTLHSALEKPCTSCGCFEAIVFYIPEVDGFGIAHRGYKGETPMGIPFSTLAGQCSGGKQVPGFVGISISYMKSPKFLQGDGGWERVVWLPKELKERVKDAIPEELYDKIATEEDVKTTDELIKFLKEKGHPCAERIGAEVEEEAIEEEEVEEEMEEVEGIEVPTMTLPGTFAGLPPGIKIVLYNAVIKAEKIIITKEEPEKKKKKKK
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).  The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA.  The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex).
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit beta 2, ACDS complex subunit beta 2, ACDS complex acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the CdhC family.