PharMolix/UniProtQA huggingface dataset:
Protein: RBL_EURFE
Sequence: SVGFKAGVKDYRLTYYTPEYETLATDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCTEAIYKAQAETGEIKGHYLNATAGTSEEMIKRAVCARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RID3_ARATH
Sequence: MEITVIASSSIDEGIGSWDLKTGTEQLQFKPCASPAHGLTAVGEKFLASSQLSARNTSGSIFYWSWTKPQAEVKSYPVEPIKALAANNEGTYLVGGGISGDIYLWEVATGKLLKKWHGHYRSVTCLVFSGDDSLLVSGSQDGSIRVWSLIRLFDDFQRQQGNTLYEHNFNEHTMSVTDIVIDYGGCNAVIISSSEDRTCKVWSLSRGKLLKNIIFPSVINALALDPGGCVFYAGARDSKIYIGAINATSEYGTQVLGSVSEKGKAITCLAYCADGNLLISGSEDGVVCVWDPKSLRHVRTLIHAKGSRKGPVNNIQIVRKTIVANSNKTQVSWKSRGALIPPPLEKYERPVEDTMDGIVTVDPPPFSDVPVYSSFLSADLIDEQVKELQQQGSAATEMEMERLKLEYKRSLQMNEQWQKNYENLLQVVMEEEQIGGTN
What is the function of this protein?
Involved in meristem development.  Acts as negative regulator of the CUC-STM pathway in shoot apical meristem (SAM) neo-formation.
What are the official names of this protein?
Protein ROOT INITIATION DEFECTIVE 3, Root initiation defective 3 protein, WD-40 repeat-containing protein RID3.
Protein: SYGA_RHOPB
Sequence: MRPERSFQGLILALQRYWADYGCVILQPYDMEVGAGTFHPATTLRALGPKPWRAAYVQPSRRPKDGRYGENPNRLQHYYQFQVILKPSPPDIQELYLKSLAAIGVDSHLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVAGVECAPVAGELTYGLERLAMYVQGVDRVYDLNFNGRDGADKVTYGDVFLQAEKEYSRHNFEHSDAAMLFEQFKMAESACQKYLAAGWDSDKREAHLMALPAYDQCIKASHAFNLLDARGVISVTERQSYILRVRELAKACGAAWLHTEAGGSSPSTSRQGEAPRGESQ
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_METMA
Sequence: MCGIVGYAGRNAAAPVIIESLKKLEYRGYDSAGVTVLGSGVETYKAVGKIINLESEIPKNLKGAIGIGHTRWATHGRPSTENAHPHNSGGNPVKISLVHNGIIENYMALKERLIGEGYEFKSETDTEVIAHLLHKHIYGSPDGKEARNNLLAGLREALKEIEGSYALAVISADEQGKLVLARKDSPLVIGLGKGENFAASDVTAFLIHTRDVIFVDDFETAVLTPDSVEIFDREGKLKEKKIEKIEWDFEAAEKAGYEHFMLKEIHEQVSAIHNTLAGKVSELEGAIYLKELNLNDDEIKKLSRVQILACGTSWHAGLLGKYLFEQLAGIHCDIDICSEYRYRNPVMHEGTLAIAITQSGETADTLAAVREIMSYNCPTLAITNVVGSTITREANSVLYTRAGPEIGVAATKTFSTQLILLYLLAVKFALVRGKLSPDYVKSFITEIRKVPGEIQQILNQKEVIRECAENFACSKSYFFLGRHLSYPIALEGALKLKEISYVHAEGFAAGELKHGPIALLDEGAPVVAIATKGQTYEKMLSNIKEVKARDAYVIAVANINDTEIGKYADVVLRVPSCDELLAPLLSVVVLQLLAYYTALARDCAIDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_THEVB
Sequence: MNIAVIGLSHKTAPVDVREKLSVPEDVRERALQHLCGYAHIQEATILSTCNRLEIYIVTSDTEVGVREVHQFLSEWSHIPLPQLRPYLFILLHQDAVMHLMRVASGLDSLVIGEGQILSQVKRCHQLGQQYKSIGPILNRVFTGAIAAGKRVRTETSIGTGAVSISSAAVELADLRLQNLQNCRIAVVGAGKMSRLVVQHLIARGVKEIRIINRSLERAQELAQQFPEVRFELFTMTDLLPIVAAMDLVFTSTAATEPLLDRDNLGAVLVGDRSLAIIDISVPRNVHANVTELGTVQLFNVDDLQAVVAQNQEARRQLAQEAEGILEEELETFLAWWHALETVPIIRSLRQKMEAIRTQELEKALSRLGSEFADKHQGVIEAMTRTIINKILHDPTVQLQSQRDLESRQRAMQTLQDLFNLEPIEA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: DAPB_STRP2
Sequence: MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKTAELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YC03_SCHPO
Sequence: MTVDNRCSNSSLCLRNVTPKQHPARVCSNHWQLKNLISTQNTGEESNPIYYTNSVFVWKIYPNSEKVVQVGQGLSFKPLSLLGKCGYIAAGGQLGEFDYWSPTSKQTHMKLCDQHNNGIEIHRRNCDSHAEALISSNDHTIKVVDLEHGLLRKQLHFPVNMNHASVSNDGRFMVCVGDSPQVFFYEIDRSGEYHLRHTTVADTTDSSFCTSISQRNELFAVASQDSSLSVFDVRYLRTPMLTKTSSRPDPNGSIRSCHFTPPNGGPLDLLLYSEGFSYSHLLDLRTGKDVELVLPSEDRFFSPASQDIFGSCFADDGSSVYVASATHLYEWNIDKRSRICFPSYQLL
What are the official names of this protein?
Uncharacterized protein C4G3.03.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BIOB_WIGBR
Sequence: MKNKSIWNLKNTKKLFYKPFFDLMFKAQKIHRKNFSSNKIQISTLLSIKTGLCPEDCKYCSQSSRYKTGLVSEKLIKIEKVINAAKKAKKSGVTRFCMGAAWKNPKDKDIPLLEEMIKSVKKLGLETCMTLGMLNDYQANRLHNAGLDYYNHNLDTSKEFYKKIITTRKYEDRISTIQNVRNAGIKVCSGGILGLGESDKDRIKLLIQLANLPKPPESVPINMLVRIKGTPMEKNKDVDAFDFIRIIALARIMMPKSRIRLSAGRENMNEQTQALCFMAGVNSIFYGCKLLTTTNSSSKRDALLFKKLNMKMEKIKNKEKYFNKKQNSDLYENKNYYNAVC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: POK18_HUMAN
Sequence: NKSRKRRNRVSFLGVTTVEPPKPIPLTWKTEKLVWVNQWPLPKQKLEALHLLANEQLEKGHIEPSFSPWNSPVFVIQKKSSKWRMLTDLRAVNAVIQPMGPLQPGLPSPAMIPKDWPLIIIDLKDCFFTIPLAEQDCEKFAFTIPAINNKEPATRFQWKVLPQGMLNSPTICQTFVGRALQPVRDKFSDCYIIHYFDDILCAAETKDKLIDCYTFLQAEVANAGLAIASDKIQTSTPFHYLGMQIENRKIKPQKIEIRKDTLKTLNDFQKLLGDINWIRPTLGIPTYAMSNLFSILRGDSDLNSKRMLTPEATKEIKLVEEKIQSAQINRIDPLAPLQLLIFATAHSPTGIIIQNTDLVEWSFLPHSTVKTFTLYLDQIATLIGPTRLRIIKLCGNDPDKIVVPLTKEQVRQAFINSGAWQIGLANFVGIIDNHYPKTKIFQFLKLTTWILPKITRREPLENALTVFTDGSSNGKVAYTGPKERVIKTPYQSAQRAELVAVITVLQDFDQPINIISDSAYVVQATRDVETALIKYSMDDQLNQLFNLLQQTVRKRNFPFYITHIRAHTNLPGPLTKANEQADLLVSSAFIKAQELHALTHVNAAGLKNKFDVTWKQAKDIVQHCTQCQVLDLPTQEAGVNPEVCVLMHYGKWMSHMYLHLGRLSYVHVTVDTYSHFMCATCQTGESTSHVKKHLLSCFAVMGVPEKIKTDNGPGYCSKAFQKFLSQWKISHTTGIPYNSQGQAIVERTNRTLKTQLVKQKEGGDSKECTTPQMQLNLALYTLNFLNIYRNQTTTSAEHLTGKKNSPHEGKLI
What is the function of this protein?
Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA.  The RNase H domain of the reverse transcriptase performs two functions.  It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid.  Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome.  Endogenous Pol proteins may have kept, lost or modified their original function during evolution.
What are the official names of this protein?
Endogenous retrovirus group K member 18 Pol protein, HERV-K(C1a) Pol protein, HERV-K110 Pol protein, HERV-K18 Pol protein, HERV-K_1q23.3 provirus ancestral Pol protein.
What is the protein family that this protein belongs to?
Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
Protein: FTSB_COXBU
Sequence: MRPIIAILIALFILLQYQLWFAAGGIVSVHHLNENINHQIMENQKLKDRNTALLADIDDLKHGAEAIEEHARNDLGMIKKNEVFYQIVK
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: PYRG_CHLCV
Sequence: MPFKCIFLTGGVVSSLGKGLTAASLALLLERQNLKVAMLKLDPYLNVDPGTMNPYEHGEVYVTNDGIETDLDLGHYHRFSSVNLSKYSTATSGQIYARVIKREREGVYLGSTVQVIPHITNEIIEVILECAKENQPDVLIVEIGGTVGDIESLPFLEAIRQFRCEHAANCFSIHMTYVPYLKAAGEVKTKPTQHSVQSLRGIGIIPDAILCRSETPLSNEVKKKISLFCNVPDSAVFNVVDVEHSIYEMPLMLSREKISTFITEKLGLFTKQEDLSDWKILIERLRNPLPNKVRIGLVGKYVQHKDAYKSVFESITHAALSLNCAVDILPLDSEDPHFLEALEECDGCLVPGGFGIRGWEGKITAAKLCRERGIPYFGICLGMQVLVVEYARNVMDLEKANSTEMDQDTPHPVICMMDGQAALVATGGTMRLGAYPCTLSPGTKVYEAYGQSEIMERHRHRYEVNFDYIQQLKDHGLNIVGRCPQQGLCEIVETENHPWMVGVQFHPEFLSKLITPHPLFVGFIQAALLYSKNKSHV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SSTT_YERPE
Sequence: MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLVVLIGCMLLVALVVNPLIVYWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQAEDAKLANPDPLAAGKSV
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSRP_TROW8
Sequence: MHRRSSKSYSSRNSKTPERSKIPDCVIASNKSAEYNYFLDKTFEAGLVLLGSEVKSVRQQKISLSEAYIYEDNSEIWLANLYIPEHKTGGWTNHNPRRLRKLLLHKYQIARLRKDLLIPGITLVPIKFYFRNGRAKLLISLARGKKLIDKREVIKEREATLEANRALKHRLRRPRAQRNTQRSVTPRSTRENKNVQRNKARSARCNVRHEN
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: CA2D2_MOUSE
Sequence: MAVPARTCGASWPGPVRTARPWPGRGPRPCPDPRGPASGPARPLLLLLPPLLLLPLLTAPGASAYSFPQQHTMQHWARRLEQEIDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIMYYDAKADAELDDPESEDMERGSKTSALRLDFIEDPNFKNKVNYSYTAVQIPTDIYKGSTVILNELNWTEALENVFIENRRQDPTLLWQVFGSATGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGTTGYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACTNKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKDAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGDKGHKQIRTLVKSLDERYIDEVIRNYTWVPIRSTNYSLGLVLPPYSTYYLQANLSDQILQVKLPISKLKDFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLDNHGYIFKPPHQDSLLRPLELENDTVGVLVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPSSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTIADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADPAEAEGSPETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHSDGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVHSFAASRHL
What is the function of this protein?
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel.  Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G).
What are the official names of this protein?
Voltage-dependent calcium channel subunit alpha-2/delta-2, Protein ducky, Voltage-gated calcium channel subunit alpha-2/delta-2.
What is the protein family that this protein belongs to?
Belongs to the calcium channel subunit alpha-2/delta family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Note=Colocalizes with CACNA1A in lipid raft fractions.
Protein: GON4L_HUMAN
Sequence: MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFEVQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGKGKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQGCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEEAPEERESTEATQSRTVRTTRKGEMPVSAGLAVGSTLPSPREVTVTERLLLDGPPPHSPETPQFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKLPGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFNIISQQLGNKTPAEVSHRFRELMQLFHTACEASSEDEDDATSTSNADQLSDHGDLLSEEELDE
What is the function of this protein?
Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A and HDAC1.  Required for B cell lymphopoiesis.
What are the official names of this protein?
GON-4-like protein, GON-4 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: ORN_WIGBR
Sequence: MNHTPILNKKNLIWIDLEMTGLNLENDRIIEIATVITDKYVKILAEGPSIAIFQSEEQLKKMNSWNIFTHTKNGLIDRVRKSKYNEKNAMIDTLKFISSWVPFGKSPICGSSINHDRLFLSKYMPDLEKYFHYRCLDVSVIKELARRWKPKILSKLKKKHTHKALDDIKDSIKELLFYKDTFIKLN
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CLONN
Sequence: MKLHELRPAEGSKKAPKRVGRGNGSGLGKTAGKGHKGQNARSGGGVRPGFEGGQMPLYRRLPKRGFTNIFAKEYVEVNVSRLNIFEDGTEVTPEVLKANGVISKVKDGVKILGNGTLEKKLTIKATKFTKGAVEKIESIGGKAEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: BIOW_BACAS
Sequence: MEEEIYYSVRMRASRDAPHEQGGKHISGGERLITYSGLQEAVNGLLHKGFSHSRGTPDFMQIQLESINQPIKTIRPLPVAVHQTDTAEKGQAVARKLLQKAGIPPHMIEKAYQNIAEYAEVRGAVLFDIQTGKRIDGRKERGVRVSRMDWPAHDFQKWTLEHKMPENPRIKEAHAIAAKVCAHPGIIAELCWSDDPDYITGYVAAKKLGYQRITKMKNAGDESGCRIFFTDGAIDTESCIHFLEKQPVFIQREGKI
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: RS19_PSEAB
Sequence: MPRSLKKGPFIDLHLLKKVEVAVEKNDRKPIKTWSRRSMILPHMVGLTIAVHNGRQHVPVLVNEDMVGHKLGEFAATRTYRGHAADKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RS8_MYCUA
Sequence: MTMTDPIADFLTRLRNANSAYHDEVSLPHSKIKANIAQILKNEGYISDFHTEDARVGKSLIVQLKYGPSRERSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAIISTSSGLLTDRQAARQGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: KGSD2_AZOBR
Sequence: MQLTGEMLIGAEAVAGSAGTLRAFDPSKGEPIDAPVFGVAAQADVERACELARDAFDAYRAQPLAARAAFLEAIADEIVALGDALIERAHAETGLPVARLQGERGRTVGQLRLFARVVRDGRFLAASIDPAQPARTPLPRSDLRLQKVGLGPVVVFGASNFPLAFSVAGGDTASALAAGCPVIVKAHEAHLGTSELVGRAIRAAVAKTGMPAGVFSLLVGPGRVIGGALVSHPAVQAVGFTGSRQGGMALVQIANARPQPIPVYAEMSSINPVVLFPAALAARGDAIATGFVDSLTLGVGQFCTNPGLVLAIDGPDLDRFETVAAQALAKKPAGVMLTQGIADAYRNGRGKLAELPGVREIGAGEAAQTDCQAGGALYEVGAQAFLAEPAFSHEVFGPASLIVRCRDLDEVARVLEALEGQLTATLQMDADDKPLARRLLPVLERKAGRLLVNGYPTGVEVCDAMVHGGPFPATSNPAVTSVGATAIERFLRPVCYQDFPDDLLPEGLQESNPLAIPRLRDGKAE
What is the function of this protein?
Catalyzes the NAD(P)(+)-dependent oxidation of alpha-ketoglutaric semialdehyde (alphaKGSA) to alpha-ketoglutarate.  Involved in D-glucarate/D-galactarate metabolism.  Prefers NAD(+) to NADP(+) as a cosubstrate.
What are the official names of this protein?
Alpha-ketoglutaric semialdehyde dehydrogenase 2, alphaKGSA dehydrogenase 2, 2,5-dioxovalerate dehydrogenase 2, KGSADH-II.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: DNAJ_ACTPJ
Sequence: MAKKDYYEVLGLQKGASENDIKRAYKRLASKHHPDKNQGSKDAEEKFKEINEAYEVLGDAEKRAAYDQYGHAAFEQGGGAGGFGGGFGGGGFGGFEDIFSEMFGGGFGSGGRRQRVVRGDDLRYDIEISLEEAVKGCKKDIRISTLAECDTCHGSGAEKGSKVETCSHCHGSGRIRRQQGFFVTEAVCPSCHGSGKKIEKPCKSCHGDGRVQKAKNLSVTIPAGVDTGNQLRLSGEGAAGENGAPAGDLYVVIHVREHDIFERDGSNLYCEVPISFTMAALGGEIEVPTLDGKLKLKIPAETQTGKLFRVRGKGVTSPRGGYAGDLICKVVVETPVALNDEQKDLLRKLEESLASKSKHRPQQEGFLDSVKNFFSNLGKH
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_VIBCH
Sequence: MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREPFDEEKMIGGLQRALEKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: LKHA4_AJECN
Sequence: MRRCTKNSRSTNPPRDPNTLSNYNAFRTTHTTVNFDILFEKQKLTGNVMHKLISLTNLEAREVILDSSFLNIHDVKVDGKQSKFELLPRQEPYGSALKIPLAEGVALSKTLDIDITVETTEKCTALQWLTPAQTSTQKHPYMFTQCQAIHARSIFPCQDTPDVKAVIDFNISSPLPVIASGVPVNDVSSSSSKSKNKVYKFHQKVPIPTYLFAMASGEIAEAPIGPRSRVAASPDKLEECKWELEADTEKFMQAIDKIIFPYIWGEYNVLILPPSFPYGGMENPIFTFATPSVISKDRQNVDVIAHELAHSWSGNLVTNASWEHFWLNEGWTTYLERRILAAVHGEPYRHFSAIIGWKALTESVERYGKDHEFTKLVVDLKGKDPDDAFSSVPYEKGFNFLFYLENLIGKDKFDKFIPHYFTKYKEASLDSYEFKSSILSFFSSDSEAHALLTSFDWDKWFYSPGLPPKPDFDTSLVDIVYALAQKWRTASESGFSPSAVDVNGLVANQLVVFLEQVLVFEKPLSAEQSKLMGDKYGLAKSENAEVLNMYFQVGLKAGDKSVIEPTAAFLSSIGRMKYVRPLYRALDKLDRNIAIEVFEKNKSFYHPICRGLVQKDLFGNKGS
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.