PharMolix/UniProtQA huggingface dataset:
Protein: YME2_ASPOR
Sequence: MDDGGNDVDSAEDGDPCDASCPLLMSPSKLASNCFNSASARSSRVNVRGCDTSFRWGRPPPSLFAAKSSLARLSSASHASYLETGHIDLKKNEGLLFINNIFPRKLQWVLEGSLRASRPYEEALKRIDRPHLAASDPLRIIRRVFPHELEVEIKEVVPRFREGGAFVKYTRNEGVKDTDIETAVKDHLEKHPIRPWFNPFQQVKVASVLGRPWIEDLYRIPSPRLRVEFLPGSANDLANDPTTESLYSLFRSYGKLRDIERQPSDSKILPRYAYVEFARPKFAVMAKNCMHGFTIAEKEGGGKFGTRLKINYERKIKLSMIKDWILSHPRIVIPAVAALIAAITVTVFDPIRTFFIKMKIKATLHVEENSVLGWIRKQVSKANIIGLGVVASDPRGLTAIWEDRQGDISQLQSWLTENTETFIIIHGPRGSGKRELVLDQALENYKYKVVIDCKQIQDARGDTAKIARAAGQVGYRPVFSWMNSISSFIDLAAQGMIGTKAGFSETLDAQLSNIWQSTATALKGVILDSRKKNDKDAHLTDEEYLEAHPELRPVVVIDNFLHNASEDNVVYEKITEWAAGLTSANIAHVIFLTTDVSFAKPLSKALPNSVFRTISLGDCSLEVGRRFVLNHLADEARTGDKPPRSEEYLEDLDSCIEILGGRVTDLEFMAHRIEAGETPNGAVNRIIEQSTSEILKMFILSTNTEAQWSHEQVWHLIKMLANSKEGSLPYNQVLLSDLFKENGEVALQALEQAELISVSSINGCPETVKPGKPVYRAVFKKLTENKTLSSRLDLEILSRLISKENKSIGKYEEELRLLGSLPKQPRELTSRIQWLLQKVYNSQNKISRYETESAFLQMILRRGH
What is the function of this protein?
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape.  Involved in the regulation of mtDNA nucleotide structure and number.  May have a dispensable role in early maturation of pre-rRNA (By similarity).
What are the official names of this protein?
Mitochondrial escape protein 2.
What is the protein family that this protein belongs to?
Belongs to the YME2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: LUXS_LEUMM
Sequence: MSETVVESFTLDHTKVKAPYVRVIETQAGPNGGSITNYDLRLTQPNETSIETGGLHTLEHLFAGLVRDEIDGIIDMSPFGCRTGFHVISWVNYDSETLAKVFKKVLEKIVSDEVTEVPAAEIESCGNYKDHSLHSAKEWAKIILAQGISSDAFERKIV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: PA2BH_LATLA
Sequence: MYPAHLLLLLAVCVSLLGASAIPPLPLNLIQFTYLIECANKGRRTSFNYADYGCYCGIGGSGTPVDKLDRCCKTHDECYAQAEKKGCYPKLTMYNYYCGEGGPYCNSKTECQRFVCDCDVRAADCFARYPYNNKNYNINTSKRCK
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 PC17, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MUKF_PHOLL
Sequence: MSEYSQTVPELVSWARKNDFSISLPVERLAFLMAIAVLNSERLDGEMSESELVDAFREVCKGFEQTTESVAVRANNAINDMVRQKLLNRFTSELADNNAIYRLTPLGMGISDYYIRQREFSTLRLSMQLSVVASELHRAAEAAEEGGDEFHWHRNVFAPLKYSVAEIFDSIDMSQRVMDEQQSSVKEDIAALLNQDWQAAIANCEQLLSETSGTLRELQDTLEAAGDKLQANLLRIQEANMDSGGSELVDKLVFDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRIFSQRLRQSVQHYFDNPWTLTIANAERLLDMRDEELTLRNEEVTGELPLALEYEEFSEINEQLAEMIEKALLIYRQEQRPLDLGAVLRDYLAQHPLSRHFDVARILVDQAVRLGVAEADFSGLPAEWLAINDYGAKVQAHVIDTY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: PYRE_PODAS
Sequence: MSELPQYKKDFLKSAIDGNILKFGSFLLKSGRTSPYFFNAGDFYRADLLNSISTAYALTIDSLPIQYDIIFGPAYKGIPLATAATIKLGQIRPRAKYAVGRVLVRDRKEAKDHGEGGNIVGAPLKGKRVLIVDDVISRCTAKREPSPRLEKEGGIVAGIVVALDRMEKLPAKDGDDSKPGPSALGELKKEYNLPIYAILTLDDIIEGIKGLVGEEDIKRTEEYREKYKATD
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: VM3V3_CROVV
Sequence: MIQVLLVTICLAAFPYQGSSIILESGNVNDYEIVYPRKVTALPKGAVQPKYEDAMQYELKVSGEPVVLHLEKNKQLFSKDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLKLPDSEAHAVYKYENVEKEDEALKMCGVTQNWESYEPIKKASQLVVTAEHQKYNPFRFVELFLVVDKAMVTKNNGDLDKIKTRMYEIVNTVNEIYRYMYIHVALVGLEIWSNEDKITVKPEAGYTLNAFGEWRKTDLLTRKKHDNAQLLTAIDLDRVIGLAYVGSMCHPKRSTGIIQDYSEINLVVAVIMAHEMGHNLGINHDSGYCSCGDYACIMRPEISPEPSTFFSNCSYFECWDFIMNHNPECILNEPLGTDIISPPVCGNELLEVGEECDCGTPENCQNECCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTKCADGKVCSNGHCVDVATAY
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like VMP-III, CvvVMP-III, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: V218_FOWPN
Sequence: MLSLYYAINYKNRKMVERLLREGVHPDSTIKGFYRPLVKSILLRDVDLVSILLQNGANPNNINDETVSPLAIAIKVNSPTIVSLLLDYNADTSLFPLYVSFPIIKVLVYHGIDVNVIDRESRSFLHYAAKNDDVDTVISLILHGANVNVQDSKGLSPLHHAVSKKTTLTAKILLENGARVNIRDSLGRLPLHLGANTYEMVKLLIDYGSPIDIKDVNGSTPLHYAIWKSSLDTIRLLVNVSTINALDNNCNSPLHYIILSETEILVELLLRGADITIKDICGNTPLDILCKLRIKKLDNIKAIISNAFLMREVVPDLLKLCGFESNRKIISNISDLKQHEVSCIKEIHLMKEHSFRKNGPTILDVCTDKVHFLHRLVNARDNVQYKDFPIYCKYIKFRIEKAIYKKTIIEKTILLLDDILIKHEYTSWHDLPYELKHYIIEYINIEFIKSLLEHTNLKNKE
What are the official names of this protein?
Putative ankyrin repeat protein FPV218.
Protein: PTPRF_RAT
Sequence: MAPEPAPGRRMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQIGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPASSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGNVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKAESDTRIQLSWLLPPQERIIKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAKNRAGPGEEFEKEITTPEDAPSGFPQNLRVTGLTTSTTELAWDPPVLAERNGRITNYTVVYRDINSQHELQNVTGDVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPMEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGTSAGGLQHLVSIRTAPDLLPQKPLPASAFIEDGRFSLSMPQVQDPSLVRWFYIVVVPIDRVGGNLLAPRWSTPEELELDELLEAIEQGEEKQRRRRRQAERLKPYVAAQVDELPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRIATVVMMTRLEEKSRVKCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLAGSKARASRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT
What is the function of this protein?
The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase F, Leukocyte common antigen related, LAR.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UBIA1_CHICK
Sequence: MGPAELVQKISINAESPRGGERNDCGAGAERGPAGGWRQKCAAYVLALRPWSFSASLTPVALGSALAYRAEGALDPRLLVGSAVAVLAVHGAGNLVNTYYDFSKGIDHKKSDDRTLVDQILEPQDVVRFGVFLYTVGCICAAGLYAVSTLKLEHLALVYFGGLSSSFLYTGGIGFKYVALGDVVILITFGPLAVMFAHAVQVGYLSVSPLLYAVPLALSTEAILHSNNTRDMESDQQAGIVTLAIIIGPAFSYVLYTVLLFLPYLIFCVLATRYTISMALPLLTIPMAFSLERQFRSQNFNKIPQRTAKLNLLLGLFYVFGIMLAPAGALPKL
What is the function of this protein?
Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10.  MK-4 is a vitamin K2 isoform required for endothelial cell development.  Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4.  Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme: coenzyme Q10, also named ubiquinone, plays an important antioxidant role in the cardiovascular system.  Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress.
What are the official names of this protein?
UbiA prenyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion.
Protein: NUSB_STAA9
Sequence: MSRKESRVQAFQTLFQLEMKDSDLTINEAISFIKDDNPDLDFEFIHWLVSGVKDHEPVLDETISPYLKDWTIARLLKTDRIILRMATYEILHSDTPAKVVMNEAVELTKQFSDDDHYKFINGVLSNIKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ARRH_LIMPO
Sequence: MIPLLSLFYIVAVKVFKKTAPNGKITVYLGKRDFGDHGSYCEPVEGVLLVDNEYLKGRKVFGQVTTTFRYGREEDEVMGLHFSRQLYLALEQVLPTKKNEAPSDFQNRLVRKLGTLAHPFTFALPENAPPSVTLQPGSEDQGRPLGVEYELKLFIAETEDEKPHKRNSVSMAIRKLQYAKPSPLAKQPSALVSKGFMMSSGKLQLEVTLDKELYFHGDKVSANVTISNYSKKTVKNIKVAVVQNTEVTMVNGHFHKTISSIESKEGCPITPGATLSKVYTLLPLASQNKDKRGIALDGMLKEGDTNLASSTLNSTGDAIGIVISYVIRVRLYMGAIGGELVADVSFKLANPEPVPVVPGSQESKAQQEKARMKKQLSREMSTDLIVEDFARRRQFSEDNE
What is the function of this protein?
Plays an important role in the photoreceptor transduction.
What are the official names of this protein?
Arrestin, lateral eye.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: HV434_HUMAN
Sequence: MDLLHKNMKHLWFFLLLVAAPRWVLSQVQLQQWGAGLLKPSETLSLTCAVYGGSFSGYYWSWIRQPPGKGLEWIGEINHSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCAR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 4-34, Ig heavy chain V-II region ARH-77.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: ARCC2_STAES
Sequence: MSKIVVALGGNALGQSPKEQLDLLKSTSKSLVSLIDKGYEIVISHGNGPQVGSINLGLNYAAEHKQGPPFPFPECGAMSQAYIGYQMQESLQNELHSMGIDKEVVTLVTQVQVASDDSAFNNPTKPIGLFYTKEQADKFTKEKGYTFVEDSGRGYRRVVPSPQPISIVELDSIETLITHGTLVIAAGGGGIPVIKENEVYTGVDAVIDKDKTSALLAAHLQSDQLIILTAVDHVYINYGKENQRGLDEVSVDEMKKHISDGQFAKGSMLPKVEAALQFLEKNTKGSVLITSLAGLGDALDGKIGTLIKN
What are the official names of this protein?
Carbamate kinase 2.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_MARMM
Sequence: MLHAVTDSSASGPADGQAGAPKFRRVLLKVSGEALMGSQNYGIDIDTADRIAREVAAAVKGGTEMCLVIGGGNIFRGLSGAAKGMDRAAADYMGMLATVMNALAMQTALERIGVQTRVQSAIPMTTVCEPYIRRRATRHMEKGRVVIFAAGTGNPFFTTDTAAALRAAEMGCDALLKGTQVDGVYSDDPRTNPDAERFDQLDYLDVLTRDLRVMDASAVTLMRENAIPIVVFDIHKTNGLARVLAGEGKCTMIGKMKSDAAAV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROD1_YEAST
Sequence: MFSSSSRPSKEPLLFDIRLRNLDNDVLLIKGPPDEASSVLLSGTIVLSITEPIQIKSLALRLFGRLRLNIPTVLQTVHGPHKRYSKFERNIYSHFWDDFNIKSYFQNLYDNHNNGKITISSKSSTNLAALPKRKRALSTASLISSNGQTSASKNYHTLVKGNYEFPFSAIIPGSLVESVEGLPNAAVTYALEATIERPKQPDLICKKHLRVIRTLAIDAVELSETVSVDNSWPEKVDYTISIPTKAIAIGSSTMINILIVPILKGLKLGPVRISLVENSQYCGSYGGVINQERMVAKLKLKDPLKHVAQIKKKRSLNEAADEGVDTDTGEFQDKWEVRALLNIPASLTKCSQDCRILSNIKVRHKIKFTISLLNPDGHISELRAALPVQLFISPFVPVNVKTSDVIERTLKTFGPSYQVTSQHDNSFSSKNFVDDSEEDVIFQRSASALQLSSMPTIVSGSTLNINSTDAEATAVADTTMVTSLMVPPNYGNHVYDRVYGEVTNEDETSASASSSAVESQAIHNIQNLYISDSNNSNNPILAPNPQIKIEDDSLNNCDSRGDSVNNSNLNLVNSNLTISENWNNNSPSANRYNNIINAGLNSPSLTPSFAHLSRRNSYSRQTSSTSLKNDLELTDLSRVPSYDKAMKSDMIGEDLPPAYPEEELGVQENKKIELERPQILHHKSTSSLLPLPGSSKSSNNLKRSSSRTHLSHSPLPRNNSGSSVSLQQLARNNTDSSFNLNLSFTSAKSSTGSRHFPFNMTTSFTSNSSSKNNSHFDKTDSTSDANKPREEENYTSATHNRRSRSSSVRSNNSNSPLRQGTGSFANLMEMFTKRDRS
What is the function of this protein?
Mediates resistance to o-dinitrobenzene, calcium and zinc.
What are the official names of this protein?
Protein ROD1, Resistance to o-dinitrobenzene protein 1.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Membrane-associated or associated to a complex that cofractionates with plasma membrane.
Protein: RNPA_CLOAB
Sequence: MKENRIRKNAEFRRVYRKGKSFSNRLLVLYVYKNYILKDINRIGISVSKKVGKSVVRSRVKRLIGESYRLNSSNLKKGHDFVIIARTACNGKRYSDIEDSIKNLFNKAGLVIYDEKNIT
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: HIS81_DECAR
Sequence: MSLADQALSYVRAISPYQPGKPITELAREMGIPVEKIVKLASNENPLGMSPKARKAVEAAISGIERYPDQFDLIAKVAERCGVSSNQIVLGNGSNDVLDLIARVFLAPGRSAVFAQHAFAVYPLATLSTGAELISTPAKNYGHDLNAMRAAIRPDTRIVWIANPNNPTGNFLPYPEVRAFLEVVPKDVVVVLDEAYNEYIPPAERVDTATWIKDFPNLVVCRTFSKIFGLAGLRVGYALASTEVADLMNRIRQPFNVNNLAIAAAVAALDDHLFVADSYELNRRGMEQIIAGLKRFGLEHIPSHGNFVTFRAGDAAVVNQKLLKQGVIVRPIGGYGLPEWLRVTIGTEPENARFLEALEKAL
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SLOU_DROME
Sequence: MVMLQSPAQKASDSASAQNTAVGGLMSPNSNPDSPKSNTSPDVASADSVVSGTGGGSTPPAAKIPKFIISANGAAVAGKQEQELRYSLERLKQMSSESGSLLSRLSPLQEDSQDKEKPNHNNNNSLTNHNANSNTRRSQSPPASVGSVSFSSPAQQRKLLELNAVRHLARPEPLQHPHAALLQQHPHLLQNPQFLAAAQQHMHHHQHQHHQHPAHPHSHQHPHPHPHPHPHPHPSAVFHLRAPSSSSTAPPSPATSPLSPPTSPAMHSDQQMSPPIAPPQNPPHSSQPPQQQQVAAPSDMDLERIKLVAAVAARTTQASSTSALASASNSVSNASISISNSSSGSPSGRDLSDYGFRIQLGGLAAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSNDGSHSTPSVCPVDLTRSVNSSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNKLPSGPFGHPRQWSYERDEEMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDVNSPTIPPPGGGSFGPGAYASGLLYSHAVPYPPYGPYFHPLGAHHLSHSHS
What is the function of this protein?
May play a role in specifying the identity of particular somatic muscles and neurons of the CNS.
What are the official names of this protein?
Homeobox protein slou, Homeobox protein NK-1, Protein slouch, S59/2.
What is the protein family that this protein belongs to?
Belongs to the NK-1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF3_STRCO
Sequence: MSAEPRINDRIRVPEVRLVGPSGEQVGIVPLAKALELAQEYDLDLVEVAANARPPVCKLMDYGKFKYESAMKAREARKNQAHTVIKEMKLRPKIDPHDYDTKKGHVVRFLKQGDKVKITIMFRGREQSRPELGYRLLQRLAEDVADLGFVESNPKQDGRNMIMVLGPHKKKTEAMAEARQAQEARKADAKANPGKSQNAAETDDAEAEAPAEAPAEA
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_VEREI
Sequence: MKVKTRSKKVNKAWLDQHVNDPYVQRARKEGYRARAAYKLREIDEQLGLIRPGYTVVDLGATPGAWSQYLRRRMAAEGAIIALDILPMEPLEGVTCLHGDFRAPDVQQRLEQALAGRVVDVVVSDMAPNLSGIACADAARMADLVELAVAFSCRHLKPDGALLVKLFHGSGYSDLAALFKQTFLRVVPLKPKASRDKSSETFLLGRGLKKASPNGLDSRSGTAAEPAPLVPIGTNSMPANGD
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO1_ORYSI
Sequence: MGEITNVMEYQAIAKQKLPKMIYDYYASGAEDEWTLKENREAFSRILFRPRILIDVSKIDMSATVLGFKISMPIMIAPSAMQKMAHPDGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRNVVEQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPYLTLKNFEGLDLAEMDKSNDSGLASYVAGQIDRTLSWKDVKWLQSITSLPILVKGVITAEDARLAVHSGAAGIIVSNHGARQLDYVPATISALEEVVTAAAGRIPVYLDGGVRRGTDVFKALALGAAGVFIGRPVVFALAAEGEAGVRNVLRMMREEFELTMALSGCTSLADITRAHIYTDADRLARPFPRL
What is the function of this protein?
Catalyzes the oxidation of glycolate to glyoxylate, with a reduction of O2 to H2O2 (By similarity).  Is a key enzyme in photorespiration in plants (By similarity).  Can exert a strong regulation over photosynthesis, possibly through a feed-back inhibition on Rubisco activase.  Does not seem to play a role in oxalate accumulation (By similarity).
What are the official names of this protein?
Glycolate oxidase 1, GOX 1, OsGLO1, Peroxisomal (S)-2-hydroxy-acid oxidase GLO1, Short chain alpha-hydroxy acid oxidase GLO1.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MSRA_BRUC2
Sequence: MSFFDSYRKKMQMPSKEEVLPGRVQPIPTAAAHFVSGHPLKGPWPDGMKQVLFGMGCFWGAERLFWQVPGVYVTAVGYAGGITPNPTYEETCTGLTGHAEVVLVVYDPKVVTLNELLALFWEEHDPTQGMRQGNDIGTTYRSVIYTFNAVDRAVAEKSRDAYSQALASRGLGPVTTQIADAPDFYYAEDYHQQYLAKNPDGYCGLRGTGVSCPIPLAH
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: AMPA_ECO8A
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_SYNPW
Sequence: MSQSDLESSMRKSVEATQRNFNTIRTGRANSSLLDRISVEYYGAETPLKSLATLSTPDSQTIQIQPFDISALALIEKAIAMSELGFTPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNLRRDAIDKIKKQEKEGEFSEDQSRDAQDSVQKTLDKFIAEVEQHLATKEADILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.