PharMolix/UniProtQA huggingface dataset:
Protein: ACP_CHLSY
Sequence: MASPEMEERLRKIIVDQLGVEPEQVVPSASFTKDLNADSLDLVELIMSIEEEFGVEISDEEAEKIQTVADALNYLETHQSNE
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_BACC0
Sequence: MHILVVSVNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLEIEEVAPYLTIFEQDGAIDHLFRVTCGLDSMVVGETQILGQIKDSFLEAQQVKATGTIFNELFKQVITLAKRAHSETTIGESAMSVSYAAVELGKKIFGELTDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTLSKAEIMAEKYMGHAKPLSELQCALLEADILISSTGASDYVITKEMMTKVEKMRSGRPLFMVDIAVPRDIDPAIDELEGSFLYDIDDLQGVVEANRAERLKEAEKIQFMIEEEIVLFKTWLSTLGVVPLISALRDKALAIQSETMESLERKIPNLSDRERKVISKHTKSIINQLLKDPILVAKEIAAEEGADEKLALFAKIFDLEMEDVESRAEEVEHKRVWTPSVPSL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RTCA_PSEMY
Sequence: MNKDFIELDGAIGGGQILRSALSLSMLTGKPFRIHNIRAKRSRPGLLRQHLTAVTAAAQISSADAEGTQIGSQSLSFAPGAIRGGDYEFAIGTAGSCSLVVQTLLPALLHADQPSRVRISGGTHNPLAPPFEFLERAWLPLLKRMGAQVEIELLRHGFAPAGGGALVMQVTPSALRPLHLETPGPIHSQQATALVADVPGHVAERELARVGKRLKWPEQALKGIWLDKQIGPGNVLLLEIACGEVTELFSSIGQSGVRAERVADQAVDQARQWLHSGAAVDEHLADQLLLPLAMAGGGSFSTTHMSEHLSSNIQVIRQFLNVEIVCTQANERILRVELRQG
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_UREPA
Sequence: MSGSSSQFSPGKLVPGAINFASGEIVMNEGREAKVISIKNTGDRPIQVGSHFHLFEVNSALVFFDEKGNEDKERKVAYGRRFDIPSGTAIRFEPGDKKEVSIIDLAGTREVWGVNGLVNGKLKK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAT36_CAEEL
Sequence: MSGKDNKGSIRFEIQNFSGLAKATEHKPVQIGHVEWILGAFTSTSDATNNAKHLGIHLKCNEELRSNLWSCDASIRFSLLRLNSNEDDDAFSMEFQQKFDDLNKIVVVNNFKNWEEAICYDNRFVLDKHAVLEVQITVNKIAGIHERIIETFDQPKEHLTDVVLVLEGKHVHVGKQVLATSSQFFQKMFYSNFAEKTQAEIKIDDVTHSEFIDLLNVIYPTHMLINSSNVSHLLKLSDRFAVPRVLEKAETFLILDQKTHLIDKLKFAEVYRLSRLQNACLSQLETSEDVTALKHHENYKSLDHITYNALLQKLIDLLED
What are the official names of this protein?
BTB and MATH domain-containing protein 36.
Protein: UNC83_CAEEL
Sequence: MDVMDSFSEVEMPNDISSEDHLLKVIESSAEEVDIFLENCSSLYNLILDSLHNLTSKTISCECLDEMTSTLEKSAKKILAERPEAENSVLLRLNTICCAMDQLRVQHNSRMMSGADSDTASSARSSTSSSTGEMRLWLHEVERRLEINEKRIRVEPNLQLLLSDQQALQLEIQHEGQLLVNRLNKQIKDDHDSDSSEEEKRKTCVDAIRKRWHTIYLNSLSLVCRIEELINHQQASEDSESDPDLVGPPIKRARIRTVGHLTASDTEESEADEEDRHSQTETVVTEDDNVLPFAENEYESIMDGRVTVDSCTSSSEDQMVEQSTNKKWESVLQDVGYSSGENSIHEALNTCADHLVPETSDMRRKRIECSPVKAFYRTVQLEDMSDLEVTKAINHDVEEEPNLSDSMYVNHDSTFLATQNLPEYDEVMALMDDDDLPMDMSMTESFNTKWREIHGQKKPLRRASRPSREQMNLIAKSSCDASSEDSSEGENQTNLEDDPEMMSVSFNSAQFDTSSPLKRQRSARGLKNASFLYDSLEMDGSFCSTRSEMLPPCKTRSLARRKLRVRRMPRSMSDGEQLGVVSSKPEGMMTPMIRVSPPSTPVRRLLRKLDEQIRNRDSDTAPEHSDAAQAYEWDEYNPPQKDDSISDRHIQTMTDISDQLMNIDDDFAEHFGTSSAIRLIEESKSHLRVVLKALEESDSNIPQLSNFELIARSNLRQVDEALKIQSGNQPSFLETSTLQDLRSEWANLYESIRSPFARIMHQVKKFAATLQEVSSMASLGDVDIRSKEDVAKTLDAVTAIERRLSSERQELRDLLASSSFRDVAKDLSCEFESVSEGYDDAVDKIGKMAHSLSQVKGEWDAWNSRQNDIRNAMVRIESHLKEGQMDNKMIADEMELCQERMNSLETMCNYLTASLGSIQNESNSKNLPDFKAELSIYSNALARLKDRFNDMIRVPTPPTVQFHPPEPLPSLARSMTTQTAEMESETENEPLTIAEAISSSRLIKFTFALSLLAALAAIFYYHVFGKPFGPHVTYVNGPPPV
What is the function of this protein?
Cargo-specific adapter that is involved in nuclear migration during development and thereafter (PubMed:11748140, PubMed:19605495, PubMed:20005871, PubMed:20921138, PubMed:27697906).  Component of the unc-83-unc-84 LINC (LInker of Nucleoskeleton and Cytoskeleton) complex where it interacts with unc-84 to form a bridge connecting the nuclear envelope to the cytoskeleton which allows for nuclear transport along microtubules (PubMed:11748140, PubMed:16481402, PubMed:25023515).  Within the complex, connects the nuclear envelope to the microtubule cytoskeleton through the kinesin-1 light chain protein klc-2 (most likely within the Kinesin 1 motor complex) to regulate nuclear migrations (PubMed:19605495, PubMed:20921138).  Moreover, within the complex, also recruits the large microtubule-associated bicd-1-dlc-1-egal-1 and lis-1-nud-2 complexes to the nuclear envelope to regulate both the bidirectional migration of nuclei and the extent of nuclear migrations (PubMed:20005871).  Not required for centrosome attachment to the nucleus (PubMed:11748140).
What are the official names of this protein?
Nuclear migration protein unc-83, Uncoordinated protein 83.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass type IV membrane protein. Nucleus outer membrane; Single-pass type IV membrane protein. Note=The transmembrane domain associates with the nuclear envelope (PubMed:11748140). Co-localizes with unc-84 and lmn-1 at the nuclear envelope (PubMed:11748140).
Protein: GRZ1_RAT
Sequence: MNLLLLLLTVSLAPTTEAAEIIGGHEADPHSRPYMAYLQYKNEDSRDTICGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKTQQVIPVVKIIPHPAYNAKTISNDIMLLKLKSKAKRTRAVKTLSLPRSNFKVKPGDVCYVAGWGKLGPMGKFPDKLQEVELTVQEDQECETYLKNAYDKANQICAGDPKIKCASFQGDSGGPLVCKKVAAGIVSYGRKDGSTPRAFTKVSTFLSWIEETMKKS
What is the function of this protein?
This enzyme is necessary for target cell lysis in cell-mediated immune responses.
What are the official names of this protein?
Granzyme-like protein 1, GLP I, Granzyme-like protein I, GLP-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
Protein: RS18_RICFE
Sequence: MLKSNNASETATRKVGDKTAKKVFFRRRKGCPLSVPNAPVIDYKNPELLIKFVSEGGRMLPSRITNVCAKKQRKLNNAIKIARILALLPFVFQAK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RL18_STRP4
Sequence: MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DPOL_HIS1I
Sequence: MAKCDKSLEAIDLDRAYTAPRKAKWAENKRINGLDTETSDGDIFCISVCWEGEKPMVQHNDREKLTSKQVWQVLTDHKARSSLNMWYNLDFDANVVLNHVCSEEQLAELVVSGTTLANSDRTYRQYMDTDKELRKGEYLITYIQSKFLEIKDHNSHIYTHYDASQFFYTSLENAVTEWLGESKANDGLEAGLFGSQTPNQLRETVAESDCVTWTNLSLTYNVSKGDKWTIHNAKSYISKNWSDILKYAQIDAELVRDLWQEAVNVGEELDIPMGRPFSTGYLAESYLDNRLREKPGLGPMPMAKMAWESYAGGRFEVLKRGNVGRVAGPDINSAYPAVLAELPDPKTLRWKRAKHASISEIETADYGFMTVKVSTDPTREIQPFAVKDEKQDKLVYPSPQNTEITVVKDIFIHAYNQGYVTDYEVIDCWLGYKTEGTTFPFDFIPELYDNRKTAEANGLEKRGLLLKIVLNSMYGKTCQTTPKRRELAESTELELHESYVPDMSLPKMIREKYSEGFIESLTAGAWFNPFLASYITGLTRLELHKQICKHDLEENTVMLATDCVMIEEKPFEESNFVENLVQDGLGYWDMEYKGDAFVLGAGVYQIDFDTCQKGCKDNCNKFSHKHKVKTRGFSEADLEKGLVNAAEKANGHIEIESTRPQTISEIIWSNEELSQVGNFLEQERKIKPEMDTKRKWSENTDFKKLLSTCETSLPLKI
What is the function of this protein?
Replicates viral genomic DNA.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: SELU_PSEPG
Sequence: MRPDCTDFRQLFLDDVPMMDMRAPVEFAKGAFPGVVNLPLMNDQERQKVGTCYKQQGQAAAIALGHQLVSGTTKQARMDAWVAFTQANPQGYLYCFRGGLRSQIVQGWLRDEAGIQYPRVKGGYKAMRTFLLETTQQAVAQCDFVLLGGLTGTGKTDVLHQLDNVLDLEGHANHRGSSFGKRATAQPAQIDFENQLAIDVLKKRARGCEQFVLEDEGRIVGSCTVPLELYQGMQQYPLVWLEDSFANRVERILRDYVVNLSAEFIAVHGEEDGRRLFAERMLQSMANIYKRLGGERYQRLSEILRLALEEQQRSGAVDLHRGWIEGLLNEYYDPMYAYQRAAKAERIEFAGDAVEVREYLKARARRQPHH
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: PA_I00A1
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVEPEDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCIENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKTTPRPIRLPDGPPCFQRSKFLLMDSLKLSIEDPNHEGEGIPLYDAIKCMRTFFGWKEPSVVKPHGKGINPNYLLSWKQVLEELQDIESEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDDCKDISDLKQYDSDEPELRSFSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIVKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLIRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENRSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: MGRB_SALT1
Sequence: MKKFRWVVLGIVVVVCLLLWAQVFNIMCDQDVQFFSGICAINKFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway (Probable).  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RR7_CANWI
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDSIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATP5J_RAT
Sequence: MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.  Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes (By similarity).
What are the official names of this protein?
ATP synthase-coupling factor 6, mitochondrial, ATPase subunit F6, ATP synthase peripheral stalk subunit F6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase subunit F6 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: THRC_BUCAP
Sequence: MKLYNLKNHNEQVNFETAVKLGLGQKQGLFFPVKLPIMTPVELSKILKMDFITRSTEILSKFISSEISKEVLHEHVKKAFSFSKPLKICINKNISCFELFHGPTLAFKDFGARFMAQMILCLNKKNESFTILTATSGDTGAAVAHAFYGMKNIRVIILYPKGKITLLQEQLFCTLGKNIKTISINGSFDDCQKLVKKAFDDKKLKESIGLNSANSINISRLLAQICYYFEAFSLISEEKRKNLVIAVPCGNFGNLTAGLLAKSLGLPIQSFIACTNSNDTVPRFLNSGKWNPKKTVSTISNAMDISCPNNWPRIEELFRRKKWDLKELRFGSVSDNVTKETLKELFRMGYVSEPHAAIAYRLLHDQLKKEEFGLFLGTAHPSKFKDTVEKILENSISLPKELKNRNNLPLLSHNINPDFNKLKEFLLEK
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: DHYSC_TRYB2
Sequence: MAELAKSAVLVSSCTDDLLGDAKQVVVGPNQEDLHSAEAVLNRYSTVGFQASNLARAFSICEMMLTPQSPSPSLMPTEGDQASESPVMVQPTLFVGVTANLFGTGCREAIRFLCTECVPLPNGVEPATPLDDMAGISCDGTGALKPSPCDSRALIHVLVVSGGAMEHDIRRACESYKLSRDGAEEEGEQFHHPVERDRSRSKGTDCHFGNVRYNSSGVASRNLFSCVMRCLVKRLAEAQRKEKANREAAPIPEAYYDVCSWAITPSTLWYMAGLWMADIFTEALQETGEVTDEKVASEEGLKRAKSTVLYWAARNGVPIFSPSLTDGDIMEFILTAGDTGVPLLQLDLVADIHRLNRLAMRSRRTGMMILGGGVVKHHVCNANLMRNGADYAVFLNNAQEFDGSDAGARPGEAVSWGKLRLDSTAVKVYSEVTIVFPLIVVHVFVAWVRMMRSKGKENIRS
What is the function of this protein?
In association with the non-catalytic regulatory subunit DHSp, catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF5A precursor protein to form the intermediate deoxyhypusine residue.  Regulates protein levels of its regulatory subunit DHSp.  Required for cell growth and survival.
What are the official names of this protein?
Deoxyhypusine synthase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: POLI_DROME
Sequence: MDFASVLGKSEAHQRTIIHLDMDYFYAQVEEIRDPTLRSKALGIQQKNIVVTCNYVARAKGVTKLMLIAEAQRICPDLVLVNGEDLAPYRQMSQRIFDLLLNYTPLVEKLGFDENFMDVTALVELRQAHVAEALLRPPVGHTYPADGTPLSNCDCGCAQRLAIGTRIAQEIREELKLRLGITCCAGIAYNKLLAKLVGSSHEPNQQTVLVSTYAEQFMRELGDLKRVTGIGQKTQCLLLEAGMSSVEQLQQCDMDVMRKKFGFETATRLRDLAFGRDTSLVRPSGKPKTIGMEDACKPISVRTDVEERFRMLLKRLVEQVAEDGRVPIAIKVVLRKFDSQKKSSHRETKQANILPSLFKTSMCPGETGVSKVQLADGAQDKLLKIVMRLFERIVDMSKPFNITLLGLAFSKFQERKVGSSSIANFLIKKADLEVQSITSLTNTSLTSPTAESPTSDECAFRSSPTTFKPSDQFYRRRATTASPVPMLLDNGSESAATNSDFSDFSETEVEPSPKKSRIGRLLVSKRSRLAADVGDSAAEVASPSKLRVCDLRLNSRDSEKDFPMSTTPSTSTSAPAPRFRTVQPPNTLLQRIDGSLRFVTTRTASRLSSNASSTASSPLPSPMDDSIAMSAPSTTTLPFPSPTTTAVVTSSSSTATCDALTNIVCPAGVDAEVFKELPVELQTELIASWRSSLVAAVEQTNGTGAATSAAIASGAPATATTASGQKNTLYRYFLRNK
What is the function of this protein?
Error-prone DNA polymerase specifically involved in DNA repair (PubMed:11297519).  Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls (PubMed:11297519).  Favors Hoogsteen base-pairing in the active site (By similarity).  Inserts the correct base with higher fidelity opposite an adenosine template (PubMed:11297519).  Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine (PubMed:11297519).  Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity (By similarity).
What are the official names of this protein?
DNA polymerase iota.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_PSEF5
Sequence: MAQQGSGYQARYKRILLKLSGEALMGSEEFGIDPKVLDRMALEVGQLVGIGVQVGLVIGGGNLFRGAALSAAGMDRVTGDHMGMLATVMNALAMRDALERANISAIVMSAISMVGVTDHYDRRKAMRHLNSKEVVIFAAGTGNPFFTTDSAACLRAIEIDADVVLKATKVDGVYTADPFKDPHAEKFDHLTYDEVLDRKLGVMDLTAICLCRDHKMPLRVFNMNKPGALLNIVHGGAEGTLIEEGEQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX26A_PHONI
Sequence: IACAPRFSICNSDKECCKGLRCQSRIANMWPTFCLV
What is the function of this protein?
Neurotoxin.  Causes spastic paralysis and death in mice.  Moderate inhibitor of L-type calcium channels (Cav1/CACNA1).
What are the official names of this protein?
Neurotoxin PRTx26An0C3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 53 (PNTx27C4) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2017_ACTPJ
Sequence: MDNVVLMPREKLLASGAESLTDQELLAIFLRTGIKGMPVMQLSQEVLNGFGSLRELLSADLATFCRMKGLGQTQFIQLQASKEMTKRYLAQQMQVRENINEPYLAVMCFQAELESEEREVFMVMFLDNQNRLIKKEKMFYGTINQATVYPREIIKEALKCNAAAIIVAHNHPSGNCTPSESDRALTKKLEMACDLVGIRFVDHIVVGKGDYFSFEEEKFR
What are the official names of this protein?
UPF0758 protein APJL_2017.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: SPEE_CLOBB
Sequence: MELWYTEKHTEYVKFSIKVDRELYTEQSKFQRIDILESKEFGKFFTLDGLMMVTEKDEFIYHDMIVHVPMATNPNIKNVLVIGAGDGGTIRELTRYKTIEKIDMVEIDERVVEVCKKYLPKTAGKLEEERVNIVYEDGLKFVRNKENEYDLIIVDSTDPFGPGEGLFTKEFYGNCYKALSEDGILVNQHESPYYEYYAKSMKDAHEKIQGLFKINKVYQAHIPTYPSGHWLFGFASKKYDPIKDLNAEAWNSLGLKTKYYNTDLHVGCFALPTYVIDMLNENKE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_BATGR
Sequence: MAYPFQLGLQDATSPIMEELTNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTTDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATLTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKHFENWSASMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RSSA_PODAN
Sequence: MAPANLPSIFNATSQDIEQLLAAQCHIGSKNLGVHAQPYLWKTRADGVNIINIGKTWEKIVLAARIIAAIDNPSDVCVISARPYGQRAVLKFAAHTGAQAIAGRFTPGSFTNYITRSFKEPRLIVVTDPRTDAQAIKEASYVNIPVIALCDTDSPTEYVDVAIPTNNKGRHSIGLVWWMLAREVLRLRGTIYNREAPWDVMVDLYFYRDPEAEAEEKVEEEKLPGVDEEGVAAIESGFPAAGGDWEAAPAAFPAAGAATGEWSEAQGAQWETGTGAPAADWAAEPAKESSW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.