PharMolix/UniProtQA huggingface dataset:
Protein: SPEF2_PIG
Sequence: MSEILCHWLNQELKVSQTVSPKSFAKAFSSGYLIGEVLHKYELQDDFAEFSEKRISSAKLNNFSRLEPTLHLLGVQFDQNVAHDIITEKPGVAMKLLYQLYIALQRKKKSGLTGVELQTMQPLTNTKLQNMKSEAFRDRLRNLIPRQTDVSLMRVSHRFQEKYKYKDEDLVHTHLKKLENFQKLQEEQRSFNIEKQRLSRRRQNEIMAQIQAAIIQIPKPASNRTLKALDAQKMMKKKKEAEDVANEIKKFEALIKKDLQAKESASKTSLDAAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRRLLMDQLIAHEAQEEAYREEQLVSRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQYEERRLKDFQDALDREAALAKQAKIDYEEQALREKEMHEQIAAERVQARYKKHYSICAEILDQILDLSTKVADYRMLTNNLIPYKLMHDWKELFFNGMPIYEQASLKHLSAKPSTEQLIELEKRDLLDNNDYEEYKNMVGEWALPEEMVDNIPPSDNRILGHVIHRLIEHSLPPQVESTAPELPSFAIKGCLLGKTFSGKTTALKFLQKYFPIEVLSIDTLVQEAIQAFHNNEKVSGALQLQKAAEEKASPVRQESGDRSQNLHNVLSAEGTPETEDETRLSTKKTPKAEEVIASASLSELTTRAQLGAKSEKLLKKGKSISDTLLVSIVVNAINQIPIYKGWILDGFPMTLNQAKLLEEALTGFNRNLIELEGKKSQISTLAVDPTASREVPLPPSAFDFVMLLDISDNTSLNRMNDIMAEAFLSETPHENINQRVAAENQDMDEDQNLRDQIQHRIIGFWDHWPSLEQWFTEPENILIKMNAEVDEQSLCQKVKEMFMAEIMKKENKAKKKSEEKEAEKKEEFSLPEATPPTPPAPPPSEPEKEKEAHPPHERSKTPTAKGKPASEPPHGNRESPQEGKGKKSETSPKRKGSPRGKSPGGKAPVKKSPADSTDVSPVPAVPPPSKPGSEEWVFVNEPIPEEIPLFLVPYWKLIENSYINSIKTVLRHLREGQHTVLAYLYDTRTGFQQFLRRPDHKQNFVSQWQADFNSLPDDLWEDEETKAELHQRVNDLRDRLWDICDARKEEAEQERLDIINESWLQDSTGIAMNHFFSLMQAELNRFQDTKRLLQDYYRGMECKIPTDDTKRFTRIPLVQLDNKDTLEFQLRIPLVPRRSISPESALSKPKIKALLKGNIDYSLENVELNFEADEKVVMDTWQQASLAVSHMVAAEIHQRLMEEEKENQPADTKEKPPQAAANKKVKKEPPKKKREDKKGKGKSPPMAESAPVITVEEIAEMERKNELRLRIKEEHLAALQFEERATQFRLELIKTKALAFLEDLVTKAVDVYKLMEKWLGERYLNEMASVEKLTEVARYHIETSTKIQNELYLDQEDFFINGNIKVFPDPPPPVRPPPVEKEENGTLTIEQLDNLRDQFLDIAPKGVIGNKAFADILLDLVTLNLGTNNFPSSWMHLTQPELQELASLLVINSELVDWRKFLLVAALPWPIPLEEELLETLQRFKAVDEEQLGTVTFEQYLQAGLWFTGDKDIKIPANPLEPLPFNRQEHLIEFFFRLFADHDKDPPRLDYTEMLLYFACHPDGMEGVYRALSVATGSHVFQPIETPVLVAEKTSSFIDMSPTEEYPEPEDNFISEERELQEEGEEKEEDIPENANTEMISMETLLKVFRGGNEPQDTNRFASYPKTESIYSENFIKVFQDLGSKNLEPIEVAVLLKHPFIQDLIRSYPDYKIPDIKVVLQRSEHIQGSDGESSPSRLTEEKK
What is the function of this protein?
Required for correct axoneme development in spermatozoa (PubMed:16549801, PubMed:19889948).  Important for normal development of the manchette and sperm head morphology.  Essential for male fertility.  Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis.  Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation (By similarity).
What are the official names of this protein?
Sperm flagellar protein 2, Protein KPL2.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm. Golgi apparatus. Note=Shows dynamic localization in developing spermatozoa. Localizes to the manchette in step 10-12 elongating spermatids. Detected in the basal body and neck area of step 13-14 spermatids. Localizes to the midpiece of the sperm tail in step 15-16 spermatids. During the epididymal transport of spermatozoa, expression in the sperm tail reduces and becomes concentrated at the distal part of the midpiece. Detected in the Golgi apparatus of late spermatocytes and round spermatids. Detected in the cytoplasm of Sertoli cells.
Protein: DOT1_ARATH
Sequence: MANHKNLFFLCFLIGLGLCSARRALLSSSESEAEVAAYGVNSGLSAGLGVGIGGGPGGGSGYGGGSGEGGGAGGHGEGHIGGGGGGGHGGGAGGGGGGGPGGGYGGGSGEGGGAGYGGGEAGGHGGGGGGGAGGGGGGGGGAHGGGYGGGQGAGAGGGYGGGGAGGHGGGGGGGNGGGGGGGSGEGGAHGGGYGAGGGAGEGYGGGAGAGGHGGGGGGGGGSGGGGGGGGGYAAASGYGHGGGAGGGEGSGGYVP
What is the function of this protein?
Involved in leaf vasculature patterning.
What are the official names of this protein?
Glycine-rich protein DOT1, Protein DEFECTIVELY ORGANIZED TRIBUTARIES 1.
What are the subcellular locations of this protein?
Secreted.
Protein: Y989_MYCBO
Sequence: MGLLGFGGAAAEAAQVATHHTTVLLDHHAGACEAVARAAEKAAEEVAAIKMRLQVIRDAAREHHLTIAYATGTALPPPDLSSYSPADQQAILNTAIRRASNVCWPTPRPPMRIWPRRFDAPPGTCRASRSMPNSAMRHPQCRRCRRRTATLRRSSGGGIR
What are the official names of this protein?
Uncharacterized protein Mb0989c.
Protein: SYL_STRPI
Sequence: MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQAEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALDKVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_METPB
Sequence: MEARRHSALKDSIRSIPDYPKPGIIFRDITTLLSDPRSFRRAVDSLVHPYAGGRIDQVAGIEARGFILGGAVAHQLSSGFVPIRKKGKLPHKTVSTAYALEYGTDEIEIHVDAIKPGDRVILVDDLIATGGTATAAVNLLRQLGAEVIAACFVIDLPEIGGAQRLRDLGVTVRTLMEFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDR1_CRYNH
Sequence: MSASPGLTAAAAGPDHLQARRDEKVIDSEKDALAHDAHAVNSGIPYPTATAPNVGAPTVPISVGRVSSAAEGKISRSSIAASSDTLRNSPLEKPISNAFSKSHPYKKSKFDFLKSRKKKEEEERKNKEKEKEASVLPPVSFFALFRFAAPLEIIAMVLGLVLAVAAGSCQPLMTLIFGRLTTSFTNYAVIANQISQGGLTPETSAALQAAKDDLKTQSGHNALYLMAIGIGMFLATWLYMFIWNVTGELNSKRIRERYLAAVLRQEIAYFDDLGAGEVATRIQTDCHLVQEGTSEKVALVFQYAGTFVCGFVLAFVRSPRLAGALVSILPVIMLCGGIMMTAMAKYGTAALDHIAKAGSLAEEVIGSIRTVQAFGKEKILGDKFADHIEQSKIVGRKGSIFEGFGLSIMFFVIYAAYALAFFYGGILVSNGQADSGIVINVFMSILIGSFSMAMLAPELAAVTKARGAAAKLFATIDRVPAIDSASEEGFKPDGLRGEISFENVKFHYPSRPSIPILKGFTTTFEAGKTFALVGASGSGKSTVVSLIERFYDPVSGVVKLDGRDIRSLNLNWLRQQIGLVSQEPTLFGTTVRGNVEHGLIGSRYENASLEEKFELVKKACVDANAHNFIMKLPQGYDTMVGERGMLLSGGQKQRVAIARAIVSDPRILLLDEATSALDTQSEGIVQDALDKASRGRTTITIAHRLSTIRDADRIYVMGGGEVLEQGSHNDLLANENGPYAQLVNNQKLAQEAAAEALQVDDDIEDPDDAVFIGGSSPMQEKDKQLHRAVTGRSLASIAMDDIQAKRAEEVAGEDKIPSSFGLYARLLRMNSADKFIYIIAFIAAICAGMVYPSLAILFGKALSDFEIQDPAELRHALSRSALWYFITALAAAFVIFFQSAGFSRAGWDLNGVLRKKLFTATLRHDIEWFDEERNSTGAVTSNLADQPQKVQGLFGPTLGTVVQSCATLIGGCIIGLCYGPLLALIGIACIPILVSGGYIRLKVVVLKDQRMKKLHAASAHLASEAAGAVKTVASLTREKDVRRIYSEALKAPMKLNFRTSIKSQCLFAASQGLTFCIIALVFYIGALWIIDAKYSTASFYTVLNSIVFASIQAGNVFTFVPDASKANSSAASIFRSIDNEPAINAESNEGKVLDHKHVVGHVRIEGVHFRYPTRPGVRVLRNLTIDVPAGTYVALVGPSGCGKSTTIQMLERFYDPLAGRVTLDGIDIKELNLASYRSQISLVSQEPTLYAGTIRFNILLGANKPIEEVTQDEIDAACKDANIYDFIVSLPDGFDTEVGGKGSQLSGGQKQRIAIARALIRNPKVLLLDEATSALDSQSEKVVQEALDKAAKGRTTIAIAHRLSSIQHSDRIYYFSEGRVAEHGTHQELLAKKGGYYELVQMQNLSRQ
What is the function of this protein?
Pleiotropic ABC efflux transporter that confers resistance to structurally and functionally unrelated compounds including azoles such as fluconazole (FLC), itraconazole (ITC), posaconazole (POS), and voriconazole (VRC).
What are the official names of this protein?
ABC multidrug transporter MDR1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YACG_ZYMMO
Sequence: MPSATRKNAPKGKCPICGAPTKAEFRPFCSRGCRDRDLLNWLGDAYRLPVKDLQAEDGDFD
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: NEUM_FELCA
Sequence: MLCCMRRTKQVEKNDEDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKGDAQAAEAEGNEKDEAPVADGVEKKEGEGPTPTDGAPASGPKAEETGKAGETPSEEKKGEGTPDAATEQAAPQAPVPSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAAATTPAAEDAAAKATAQPPTDAVESSQAEEKIEAVDETKPKESARQDEGKGEEREADQEHA
What is the function of this protein?
This protein is associated with nerve growth.  It is a major component of the motile 'growth cones' that form the tips of elongating axons.  Plays a role in axonal and dendritic filopodia induction (By similarity).
What are the official names of this protein?
Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43.
What is the protein family that this protein belongs to?
Belongs to the neuromodulin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, axon. Cytoplasm. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes.
Protein: DEOB_LACLA
Sequence: MPKKFGRIHLVVMDSVGIGAAPDADKFFNHDVETHEAINDVNSDTIGHISEIRGLDVPNLQKLGWGNIPRESPLKTVPKADKPAAYVTKLEEISKGKDTMTGHWEIMGLNIQTPFPTYPEGYPEDLLEKIEEFSGRKIIREANKPYSGTAVIEDFGPRQLETGELIIYTSADPVLQIAAHEDVISREELYKICEYVRSITLEGSGIMIGRIIARPYVGEAGNFERTDGRRDYALSPFAETVLEKLYKAGIDTYSVGKISDIFNTVGVKYDMGHNHNDMDGVDRLLKAMTKAEFTEGFSFTNLVDFDAKYGHRRDVEGYGKAIEDFDGRLPEIIDVMKEDDLLMITADHGNDPSYVGTDHTREYIPLVIFSKSLKDPKVLPVGHFADISATVAENFSVKKAQTGESFLDALV
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRSA_ENT38
Sequence: MTQANLSETLFKPRFKHPETSTLVRRFNPGTQPAVQSTLDGKTVPHWYRMINRLMWIWRGIDAREILEVQARIVMSEADRTDSELYDTVVGYRGGNWIYEWATQAMVWQQKATQEPDQTLSGQHWLHAANLYSIAAYPHLKGDDLAEQAQALANRAYEEAAQRLPCNMREIEFPIPGGASVTGFLHMPPGEGPFPTVLMCGGLDSLQIDYYSLFERYFAPKGIAMLTLDMPSIGFSSKWKLTQDSSLLHQHALKALENIPWVDHTRVAAFGFRFGANVAVRLAYLESSRLKAVACLGPVVHALLSDPQRQASVPEMYLDVLASRLGMHDASDEALRVELNRYSLKTQGLLGRRCPTPMMSGFWKNDPFSPEEESRLITSSSLDGKLLEIPFSPVYQNFDKGLKEITRWITQRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: APT_NITWN
Sequence: MTFEDDLQASVRTIPDYPKPGVMFRDITTLLGDARAFRRAVDQLVHPWAGSKIDKVAGIEARGFILGGAVAHQVSAGFVPIRKKGKLPHQTVRMAYALEYGTDEMEMHVDAIARGERVILVDDLIATGGTAEGAVKLLRQIGADVVAACFIIDLPDLGGAAKLRAMDVPVRTLMAFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C19_MOUSE
Sequence: MTSYSYRQTSAMSSFGGTGGGSVRIGSGGVFRAPSIHGGSGGRGVSVSSTRFVTSSSGSYGGVRGGSFSGTLAVSDGLLSGNEKITMQNLNDRLASYLDKVRALEQANGELEVKIRDWYQKQGPGPSRDYNHYFKTIEDLRDKILGATIDNSKIVLQIDNARLAADDFRTKFETEHALRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEEEITALRSQVGGQVSVEVDSTPGVDLAKILSEMRSQYEIMAEKNRKDAEATYLARIEELNTQVAVHSEQIQISKTEVTDLRRTLQGLEIELQSQLSMKAALEGTLAETEARYGVQLSQIQSVISGFEAQLSDVRADIERQNQEYKQLMDIKSRLEQEIATYRSLLEGQEAHYNNLPTPKAI
What is the function of this protein?
Involved in the organization of myofibers.  Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity).
What are the official names of this protein?
Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: MBTN_MYCTO
Sequence: MTAGSDLDDFRGLLAKAFDERVVAWTAEAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKLVELAFALGQLASAGIGVGVSLHDSAIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCIDTWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIAEQGRLELRTAAAVKVTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGMTPDHDGYAAVVGASKA
What is the function of this protein?
Catalyzes the dehydrogenation at the alpha-beta position of ACP-bound acyl chains.  This results in the introduction of a double bond in the lipidic chain, which is further transferred to the epsilon-amino group of lysine residue in the mycobactin core by MbtK (By similarity).
What are the official names of this protein?
Acyl-[acyl-carrier-protein] dehydrogenase MbtN, Acyl-ACP dehydrogenase MbtN, Mycobactin synthase protein N.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: RL36_LISIN
Sequence: MKVRPSVKPMCEKCKVIRRKGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: AROA_THESQ
Sequence: MKVLPAKKVEGVLSVPPDKSITHRALILSALAETESTLYNLLRCLDTERTHDILEKLGTRFEGDWEKMKVFPKPFAEPIEPLFCGNSGTTTRLMSGVLASYEMFTVLYGDSSLSRRPMRRVIEPLEMMGARFMARQNNYLPMAIKGNHLSGISYKTPVASAQVKSAVLLAGLRASGRTIVIEPAKSRDHTERMLKNLGVPVEVEGTRVVLEPATFRGFTMKVPGDISSAAFFVVLGAIHPNARITVTDVGLNPTRTGLLEVMKLMGANLEWEITEENLEPIGTVRVETSPNLKGVVVPEHLVPLMIDELPLVALLGVFAEGETVVRNAEELRKKESDRIRVLVENFKRLGVEIEEFKDGFKIVGKQSIKGGSVDPEGDHRMAMLFSIAGLVSEEGVDVKDHECVAVSFPNFYELLERVVIS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VLN1_ORYSJ
Sequence: MKGVDDAFLGVGDKPGLDIWCIMGSNLIAIEKSLHGKFYTGNTYIILSTVELKSGVRQHNVHYWVGEEAKEEDCLTASDKAIELDVALGSNTVQYRETQGEESDKFLSYFKPCIIPIQGSLSSHMRIYGDKSKDTTMFRCEGEHVARVTEVPFSRSSLDHKAVFVVDTESKIFLFSGCNSSMQTRAKALDVVKHLKENRHCGRCEIATIEDGKLVGDSDAGDFWNLFGGYAPIPRDVQDTVMTELMTTSSKKLFWINKRNLVPVETNLLEREMLNSDRNYILDCGTEVFLWMGMTTLVSERRTSVTALEDYVRCEGRQSNARSVILTEGHETVEFKMHFQHWPKNAVPKLYEAGREKVAAIFKHQGYDVTEIPEDKPRHFISCNGSLKVWLVDNGSVTLLCTEEQEQLYNGDCYIIRYSYIEDGKDYHLFFAWSGLNSINEDRVAAASLMSGMIDSVKGHAVVAQVFEGREPEMFFLVFKSLIIFKGGRSMAYKNFVSQRSDANGWYQKNGVALFRVQGLKHDCIRAIQVDLAASSLNSSHCYILQAGGSFFTWLGSLSSPSDHNLLDRMMDKLCPLKQSLLVREGSEPDRFWEALGGRSEYLREKQVKDWPADPHLYTCHFEQGLFKAKEVFSFSQDDLVTEEILILDCVEELHIWVGHQSGVLSKEQALDIGKMFLQAGIHQDGRRPIDTTMYIVTEGDEPRFFTSFFNWDYSKQTMLGNSFERKLAILKGISQKLETPERSLRKSSSSSLPRRSPGTSSSEPTTPEQRAAARTFASASTGKLLRERSPAALSPSLSTPSPSPRSRSSASSSPASWNSTPSTVARRLFPPSLHASAEAVATGTPRRR
What is the function of this protein?
Ca(2+)-independent actin-binding protein.  Binds actin microfilaments (MFs).  Involved in actin filament bundling, severing and capping.  Caps the barbed end of actin filaments and protects them from disassembly.  Promotes VLN3-mediated MF severing.
What are the official names of this protein?
Villin-1.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AROA_CAMJR
Sequence: MKIYKLQTPVNAILENIAADKSISHRFAIFSLLTQEENKAQNYLLAQDTLNTLEIIKNLGAKIEQKDSCVKIIPPKEILSPNCILDCGNSGTAMRLMIGFLAGIFGFFVLSGDKYLNNRPMRRISKPLTQIGARIYGRNEANLAPLCIEGQKLKAFNFKSEISSAQVKTAMILSAFRADNVCTFSEISLSRNHSENMLKAMKAPIRVSNDGLSLEINPLKKPLKAQNIIIPNDPSSAFYFVLAAIILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVKDNIAWLIDEAPALAIAFALAKGKSSLINAKELRVKESDRIAVMVENLKLCGVEARELDDGFEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDSDCIKTSFPNFIEILSNLGARIDY
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_BACCR
Sequence: MSKRDYYEVLGLSKGASTDEIKKAYRRLAKKYHPDVSKEENAIEKFKEVQEAYEVLSDDQKRAQYDQFGHAGANQGFGGFGGGGDFGGGFGFEDIFSSFFGGGGGRRRDPNAPRQGADLQYQVTLDFEEAIFGKELNVEIPVEDPCDTCKGSGAKPGTSKETCKHCSGSGQVSVEQNTPFGRIVNRQACGHCSGTGQIIKEKCTTCHGSSKVRKRKKINVKIPAGIDNGQQIRVSGKGEAGVNGGPARDLYVVVHVRNHEFFEREGDHIICEMPLTFAQMALGDEVEVPTVHGKVKLKIPAGTQTGTEFRLKGKGAPNVRGYGQGDQYVVVRVVVPTKLTSQQKDLLREFAGQEEQDDSLFGKLKRAFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSBA_XANOR
Sequence: MTNSTDRPVSVSSWRTYRRLVAFAKPYRLLLVAALIAALIEAAGTTGFLALMKPITDETFIYKNAEVSRWLPVQIILLFVVRGIAGYITDMAMGKSARSIARDLRIKVMAKYLRLPGSRFDSEPVPSMLIRLGSDSDQVAQAAVDAIKVMIQQSLQVIGALALMLWHSWQVTLTILVLAPVLAWVMDKVARRYRRISHSIQESGAHLLQAADQTLSSHQEVKIYGAQQTEMERYGALADRNLRLAMKVESTRGISTATVQMIGAIGLSALLFVAGAQALAGRLTAGDFVVLMTSMLTIIPGLKQLTNVQNMVQRGLASAERLFSVLDSPDEPDQGAVALTRAKGLIEFRDVTARYPGQVNPALADVSFIAQPGTVTAIVGRSGSGKSSLIKLIPRFYDAEAGQILLDGQPVQAYALADLRRQIALVGQQVMLFDGSIAENVAFGEMRSADASQLERAILGANAMEFVAQLPEGLQSHVGAKGGRLSGGQRQRLAIARAMLKDAPILILDEATAALDNESERLVQDALHKLMPDRTTLVIAHRLSTIEHADQVLVMDQGRIVERGTHHELLAQGGLYSHLHGMQFRERQA
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS6_CERSK
Sequence: MLKTRIIPCLDVADGRVVKGVNFVDLRDAGDPVEAARAYDAAGADELCFLDIHATHENRGTMYDLVTRTAEQCFMPLTVGGGVRTHQDVRALLLAGADKVSFNSAAVADPTVVAEAADRFGSQCIVVAIDAKTVAPGRWEIFTHGGRRATGIDAVEFACDVASRGAGEILLTSMDRDGTRAGFNLPLTRAISEAVPIPVIASGGVGTLDHLVEGVTEGGASAVLAASIFHFGEFTIGEAKAHMATAGIPVRLA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATD1B_DANRE
Sequence: MVLKEIPTENITRPLGRNEVIGLLFRLTIFGAVTYFTIKWMVDAIDPTRKQKVEAQKQAEKLMRQIGVQNVKLSEYEMSIAAHLVDPLTMQITWHDIAGLDEVITELKDTVILPIQKRHLFEGSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGFRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDYNCQVIIMGATNRPQDLDSAILRRMPTRFHINQPNVRQRKDILKLILENENVESAVELSEIAKQTDGFSGSDLREMCRDAALLCVRDFVHQESPEEDFIRPIRQEDLQRAIEKMKKSKSAGVHEAFMQVPLD
What is the function of this protein?
Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria (By similarity).  Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane (By similarity).  Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory (By similarity).
What are the official names of this protein?
Outer mitochondrial transmembrane helix translocase, ATPase family AAA domain-containing protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. MSP1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein. Postsynaptic cell membrane; Single-pass membrane protein.
Protein: GCD1_ORYSI
Sequence: MLALRKTLLHGRLPAAPPAAAAAAIASRIPALLRRLSSSPGDGQGGDEWGSSWSTGITKEHFDGSDAAVGRPVTSPSKPVSPELAAVRAMDEEDEIFRAMERDNREAKAYVDSWGDRMRETCELLKQVREPGSRGSYLKDSEKQEMYRLHKEDPETYTVERLAKDFRVMRQRVHAILWLKEMEEEEERKLGKPLDDSVEVLLDSCPEFFNSHDREFHVASLPYKPDFKVMPEGWDGTTRDPDEVLYEISMKEDQMLYEEFVQRLQFNKKKVAGEVKCHKYSRRRPDDGWTYMVEKLGVQSKRGSGGGWKFASLPDGSSRPLNDMEKMYVKRETPKRRRRIMAPFK
What is the function of this protein?
Essential for fertility (male and female gametophyte functions and development) (By similarity).  Required for the integrity of female gametic mitochondria (By similarity).  Involved in embryo apical-basal patterning, and particularly dorsal-ventral patterning, during early embryogenesis, and endosperm free nucleus positioning and development as well as early endosperm development, probably by modulating the expression pattern of related genes (e. g.  AL1, MYB3/AL2, CYP78A13/GE, PNH1, HAZ1, MPK6 and OSH1) (By similarity).  Has function in triggering of endosperm programmed cell death (PCD) leading to syncytial endosperm cellularization and starchy endosperm cell maturation (By similarity).  Implicated in central vacuole dynamics necessary for microspore development leading to pollen production, and for pollen development and germination (By similarity).
What are the official names of this protein?
Protein GAMETE CELL DEFECTIVE 1, mitochondrial, OsGCD1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PYRB_METM7
Sequence: MRHLISMRDIGREEILNILNESEKMEAILNENGHCDFLNGRILATLFYEPSTRTRLSFETAMKRLGGNVIGFTDISNTSVTKGESLADTIKVISGYSDLIAIRHPSEGAARLSSENSKVPVINAGDGSNQHPTQTLLDLYTIKREVGHIENLKIAFIGDLKYGRTVHSLCQALSLFKSVEIKLIAPDELKMPREVIEDIDGKLKLSEMTDVEIDDVDVVYMTRIQKERFVDVNEYYKVKGIYRLSKEHIGNKNVVIMHPLPRVDEIDSEVDNIPQARYFKQSFYGVPVRMAILKLLFEDSIK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.