PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_ACIF2
Sequence: MDSQPQSKKAARGADKTARNPIPIIPAPTERLPKPQWLRVRSPLSPEVDQLKKILRDAALHTVCEEASCPNLGECFGGGTATFMILGDICTRRCPFCDVAHGRPEAPDPLESVHLARTVASMKLRFVVITSVDRDDLRDGGARHFAEVISALREHCPELHVEILVPDFRGRVANALAAFRETPPDVFNHNLETVPRLYLQARPGADYHHSLQLLAAFKAQHPQIPTKSGLMLGLGEEIDEIRGVMRDLRQAGCELLTIGQYLAPSRHHLPVARFVPPEEFQQLQRDGMAMGFRHVASGPLVRSSYHAERSFHEIGGD
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYLT4_MOUSE
Sequence: MACRTLPSRRQEEETTKDLALKLPPGKPGGHLPSIDETRPIGPGPASRRGSLPGLHPSFSRRNSLAGPLVGPGGRRPSLGPVPPLGSRVSFSGLPLMLPRRMAPSYRLEPAPGEHWEAAGAQRALEAALTTQLNGVCYCGSEAGKLVQALCEQIHTRVRELNLPRYKLVCNVVLGPREGQGVHVVSRALWDAVHDGLASATFTNPSLFAVATVHAVYWE
What are the official names of this protein?
Dynein light chain Tctex-type 4, Tctex1 domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Present along the entire length of the flagellum, including principal and endpiece, and more predominantly in the midpiece region.
Protein: COX1_GEOTE
Sequence: MFINRWLFSTNHKDIGTLYMIFGAWAGMVGTGLSILIRAELGQPGSLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAITQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTIGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFTGYTLNDTWAKIHFTIMFVGVNMTFFPQHFLGLAGMPRRYSDYPDAYTTWNTISSMGSFISLTAVILMVYMIWEALASKRLVKSVPLTTTNLEWMHGCPPPFHTFEEPVFIKSPQL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSHC_CELFN
Sequence: MLSWPAPQIPRLPGTGEPVRVLDTATGRLVVAATGPHARLYVCGITPYDATHLGHASTYVAFDVLVRAWLDEGKTVTYASNVTDVDDPLLERATATGVDWRDLAAQQTALYASDMTTLGVVPPDVYRGVVESVPQVVAAVDALLSRDAAYRLPAPDGGDDVYADLSADPGFGSVAGLEHAAMLALSAERGGDPDRPGKRSPLDPLLWRAERPGEPAWDAPGLGRGRPGWHVECAVIASDGLGVPFDVQGGGSDLAFPHHESSASHLRVLTGTPQPAAAHVHTGMVGYRGHKMSKSLGNLVLVSQLVADGVEPMAVRLAVLAHRYRSDWEWTDDVLATAQQRVARWRRALSGNGGPAAQPVLDGVRAAVADDLDTPRALAVVDAWATAALAGEVPFEEGAPGVVARTVDALLGVRM
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: SYC_ECO45
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_MICLU
Sequence: MPRKGPAPKRPLVVDPVYGSPLVTQLINKVLVDGKKSTAERIVYGALEGARAKNGARSRGHPIKKAMDNIKPALEVRSRRVGGATYQVPVEVKPGRSTALALRWLVGFSKARREKTMTERLMNEILDASNGLGGAVKRREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: FABH_BURVG
Sequence: MAQSTLYSRVLGTGSYLPPDRVTNQQLADRLAKEGIETSDEWIVARTGIHARHFAAPDVTTSDLAYQAARRAIEAADIDPQSIDLIIVATSTPDFVFPSTACLLQNKLGIKSGGAAFDVQAVCSGFAYAMAMADSFIRGGQHRTALVVGAETFSRILDFKDRTTCVLFGDGAGAVILSASEEPGVLGSALHADGSYSNILCTPGNVNRGVIEGSAFLHMDGQAVFKLAVNVLEKVAVEALAKANLAPEQIDWLIPHQANIRIMTSTCRKLGLPQERMVVTVDQHGNTSAASIPMALDVAVRDGRIQRGQHVLIEGVGGGFTWGASVFRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBPB_MYCTU
Sequence: MSRAAPRRASQSQSTRPARGLRRPPGAQEVGQRKRPGKTQKARQAQEATKSRPATRSDVAPAGRSTRARRTRQVVDVGTRGASFVFRHRTGNAVILVLMLVAATQLFFLQVSHAAGLRAQAAGQLKVTDVQPAARGSIVDRNNDRLAFTIEARALTFQPKRIRRQLEEARKKTSAAPDPQQRLRDIAQEVAGKLNNKPDAAAVLKKLQSDETFVYLARAVDPAVASAICAKYPEVGAERQDLRQYPGGSLAANVVGGIDWDGHGLLGLEDSLDAVLAGTDGSVTYDRGSDGVVIPGSYRNRHKAVHGSTVVLTLDNDIQFYVQQQVQQAKNLSGAHNVSAVVLDAKTGEVLAMANDNTFDPSQDIGRQGDKQLGNPAVSSPFEPGSVNKIVAASAVIEHGLSSPDEVLQVPGSIQMGGVTVHDAWEHGVMPYTTTGVFGKSSNVGTLMLSQRVGPERYYDMLRKFGLGQRTGVGLPGESAGLVPPIDQWSGSTFANLPIGQGLSMTLLQMTGMYQAIANDGVRVPPRIIKATVAPDGSRTEEPRPDDIRVVSAQTAQTVRQMLRAVVQRDPMGYQQGTGPTAGVPGYQMAGKTGTAQQINPGCGCYFDDVYWITFAGIATADNPRYVIGIMLDNPARNSDGAPGHSAAPLFHNIAGWLMQRENVPLSPDPGPPLVLQAT
What is the function of this protein?
Synthesis of cross-linked peptidoglycan from the lipid intermediates.
What are the official names of this protein?
Penicillin-binding protein PbpB, Penicillin-binding protein 3, PBP3.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: IF2_STUS1
Sequence: MTQVTVKELAQVVDTPVERLLQQMREAGLSHTSAEQVVTDNEKQALLAHLKSSHGAKVDEPRKITLQRKTTTKLKVGGSKTISVEVRKKKTFVKRSAEEIEAEQRRELEEQRAAEEAARLKAEQEARERAEEEARRQAEAAKAQTAETAAPAAAESASSAEPAQVVAAVEAAAPAPERKKEEPRRVEKPRSDDDERRDRKHAQHRPSLKTKAPLARTVRSGEDEADGFRRGGRGGKSKLKKRNQHGFQSPTGPVVREVSIGETITVAELAQQMSVKAAEVIKFMFKMGSPVTINQVLDQETAQLVAEELGHKVKLVSDNALEEQLAELLKFEGESVARAPVVTVMGHVDHGKTSLLDYIRRAKVAVGEAGGITQHIGAYHVETERGMVTFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTQEAVQHAKAAGVPIVVAVNKIDKPEANPDNIKNGLAALDVIPEEWGGDTPFIPVSAKVGTGVDELLEAVLLQAEILELKATPSAPGRGVVVESRLDKGRGPVATVLVQDGTLRQGDMVLCGVNFGRVRAMLDENGKPVKEAGPAIPVEILGLDGTPEAGDDLTVVADEKKAREVALFRQGKFREVKLARAHAGKLENIFETMGQDEKKTLNIVLKADVRGSLEALQGSLNGLGNDEVQVRVVGGGVGGITESDANLALASNAVLFGFNVRADAGARKIVEAEGLDMRYYNVIYDIIEDVKKALTGMLGSDVRENILGIAEVRDVFRSPKFGAIAGCMVTEGMVHRNRPIRVLRDDVVIFEGELESLRRFKDDVAEVRAGMECGIGVKSYNDVKVGDKIEVFEKVEVARSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: TOG1_YEAST
Sequence: MAAKRGLAKQKSRVTKACDRCHRKKIKCNSKKPCFGCIGSQSKCTYRNQFREPIEAFFNYTGSLSNDLDNAKCSIAKLKAQLPPSAPASLQKGLANICTELEKIQPQLYLNLDSKEISSYGGLKSIETEIIGKQSKSLNRFSNAFESNTAQNVSMYFGVYSPLLYFASTGISWITKKLISCSNDRETRETIYLFLKFLDASSASHAGPKVTSISPLEYYSKLNGLSCGNDVLIQHIMSNISNEIKGNTNINQTIKFNKPTDWFMYGVQLMEQHHKALDRKSSKKLLPLKYFLEQDELIFCLCLEYFERSLFSTMYDLTILKGLVSLMKHRYWIDDPFVLGRIISTMSRRSLDAGLNRWEYYIGQDEDTAEEYRKLWWDCYWWDRWYSLVTGKQPLIPHEMTSCLFPKDVVGLGVDDSMDCFTLINLVELDPSKFDICISFGYILLTKIITAVFSGLLYNRHFTDYRLFATPNAKDLNGTARQLMVEFSKICKIFQCIQDKLIPFLKQYSENSNVFELYTHFGFAKVCCFQGMESLILRIQNLLQERERIELDSCVKDIRLQTFEASVDILTDVLKHEDTFYIFRCSWFIYAILMNITLNFIETPRRNSICYLSLMCRMIASYNDLFVSSGNVNFKGNNAFSKKLENGTAVSFILTRICCQMYTRSQKMAKESLFCELKKYGQACSDAGQAALDIECIWYRNIIGEHKESSFRKEILSILDREMGDLVNNRVIGVQGKNQEGACYEKLSPSSTSVSVGMDFCSLENFVTAESLPDLLNLFWEDTEFGITKENLGE
What is the function of this protein?
Transcriptional activator required for growth on non-fermentable carbon sources and that regulates genes involved in fatty acid utilization (PubMed:11353088, PubMed:24998441).  Acts as a direct activator that binds the promoters of oleate utilizing genes, encoded key enzymes in beta-oxidation and NADPH regeneration (POX1, FOX2,POT1 and IDP2), the glyoxylate shunt (MLS1 and ICL1), and gluconeogenesis (PCK1 and FBP1) (PubMed:24998441).  Regulates also the abundance of peroxisomes that are vital for fatty acid oxidation (PubMed:24998441).
What are the official names of this protein?
Transcription factor TOG1, Transcriptional regulator of oleate 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDHJ_ADICA
Sequence: MNTVDKEKFNLKTRGRLSAWLTKHNFSHRPLGYDYRGVEILEVKSEEWLSTAVALYAYGFNYLRSQCAYDATPGGSLVSVYHLTQMQDQSDQPEEICVKVFVSRTNPQIPSVYWVWKSAEFQERESYDMLGIIYQGHPYLRRILMPESWIGWPLRKDYVVPNFYELQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PYRF_STRPB
Sequence: MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRSIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQAIKAEWAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: COAD_NEIMF
Sequence: MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINPDKRSTYTVAERQDMLCDITKMFPNVRTDVFENRFLVHYAREVDAGFIVRGIRSASDYEYERSMRHINSDLAPEISTVFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYEKILAEHQHEN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPQ_ECO27
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPNSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: RIC8A_MACFA
Sequence: MEPRAVAEAVETGKEDVIMEALRSYNQEHSQSFTFDDAQQEDRKRLAELLVSVLEQGLPPSHRVTWLQSVRILSRDRNCLDPFTSRQSLQALACYADISGSEGSVPDSPDMDVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELKGVHLLTDTLELTLAVTPEGNPPKLLPSQETERAMEILKVLFNITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTEEFHGHAVNLLGNLPLKCLDVLLTLEPHEDSVEFMGVNMDVIRALLIFLEKRLHQTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQDAMCETMEQQLSSDPDSDPD
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins.  Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP.  Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex.  Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation (By similarity).
What are the official names of this protein?
Synembryn-A, Protein Ric-8A.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Colocalizes with RIC8A in CA2 hippocampal neurons. Colocalizes with GNAI1 and RGS14 at the plasma membrane (By similarity).
Protein: Y749_MIMIV
Sequence: MDLQKACDRISQEFETDIIMGANLLVQMIQSQRITSNTPVQTVQPVQPVQPVQSVQSVQSVQSVQSVQPVQPVQPVQPVQPVRVPEINPVLFSYLIPLIPFIQMYHIAQKDVVPKNPQVQKQDVSQFTPDGKFKIPINKTKTIKKSTSEKKTSPKKKTTSQQIKRVRLSDEERNILESQYSKNNFPSPEIRDELAKKIGKTPRQVQIWFQNKRCKDRKNLEKNN
What are the official names of this protein?
Putative homeobox protein R749.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GBB_LYMST
Sequence: MSNDLEALRQETEQLKNQIREARKAAGDTTLAQACSGVEAVGRIQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNSIVTSSGDMSCALWDIETGQQTTSFTGHTGDVMSLSTSPDFRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGRYDDFNCNVWDVLKQETHGVLAGHDNRVSCLGVTEDGSAVATGSWDSFLKIWN
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: RPOC2_CUSEX
Sequence: MEVLMAERINLVFHNKVLDRTAMKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSFIFEKYHHYGNVHAVEKLRQSIEIWYATSEYLRQEMNLNFRMTDPLNPVHLMYFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTARGISVSPHNGMMPERMFIQTLIGRVLADDIYIGPRCIATRNQNIGVGLVNRFLNFRAEPILIRTPLTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSNGKIRLNEDLVHPTRTRHGYPAFFCSIYLYVTIESQDILHHVKIPPKSFILVQNDQYVESEQVIAESRAGTSTFNYKEKVRKHIYSDSGGEMHWSTNVYHAPEFTYGNVHLLSKTSHLWILLGEPCHSSLVSTSIHRDQDQMSVQSLSVKRRSTSKLSETNDEANQEIASADFSGKKEDRIADFSDVNRSICTDHYNLVYPAILPILDENSSFFSNCLSKRRRNQFIIPLQSIQEHKNELMPCSSISMKTPPNANGIFWANSILAYFDDPRYRRNNSGSTKYGTLEMHSTVKKEDFIKYRGVNEFRQKMKVERFFFIPEEVHILPGSSSIMVRNHSLIGVDTQITLNLRSRVGGLVRVERKKKIIELKIFFGDIYFPGGADNISQHSGVLIPPGTERKTNYKESKKVKSWIDVQRITPSKKKFFVLVRPVVTYEIMDDITSATLFPPDLLQQRDNAQLRVVNYILHGTGKPIRGNYDTSIQLVRTCLVFKRNQDKKSYYSEAARASVVEIRTNYLIRHFLRIDFVKAPISYIGKRNDPLGLGLLADNGLDWTHKNPYSEARIHQNLNQNQGTIHTFLNRNKESQSLSILSSSNCSRMDPANGAKSNNVIQESKKEEYPILKISNSLGPLGTYPPIANCDSLNHLLTHNQILVTNYFKLDNVKPPFQVFKLKYYFIAENWKVCNYNPGSNLRLNVFDFHWNFLHHNSCAETSKIMSLGQFICQNVCIDKTRPPRKSGQVILVQVDSVVIRLAKPYLATPGATVHGLYGETFFGGDTVVTFNYEKSISGDITQGLPKVEQVLEVRSVDSISMNLEGRVEGWSKCITGILGIPWGFFIGAELTIVQSRISLVNKIQKVYRAQGVHIHNRHIEIIVRQITSKVLVSEDGMSNVFSPGELIGLLRAERTGRALEEPIHYRSVFLGITKASLNTQSFISEASFQETARVLSKAALGGRIDWLKGLKENVVLGGVIPAGTGFRGLVDPSKQYKTIPLKTNLFEGGMRDLLVHHRKLFDSFLNTSPS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: NFUA_PROMH
Sequence: MITITDAAQAHFAKLLANQEPNTQIRVFVINPGTPNAECGVSYCPPDAVEPNDTEIKFEKLSAYVDDISAPFLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLIERVEYVLQSQINPQLASHGGRVSLMEITEDGYAILQFGGGCNGCSMIDVTLKDGIEKELLNLFPEELKGVKDLTEHQRGDHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: ARBH_ASFE4
Sequence: MEGEELIYHNIINEILVGYIKYYINDISEHELSPYQQQIKKILTYYDECLNKQVTITFSLTSVQEIKTQFTGVVTELFRDLINWGRICGFIVFSARMAKYCKDANNHLESTVITTAYNFMKHNLLPWMISHGGQEEFLAFSLHSDMYSVIFNIKYFLSKFCNHMFFRSCVQLLRNCNLI
What is the function of this protein?
Suppresses apoptosis in host cell to promote the viral replication (By similarity).  Has the ability to potentially bind to all the members of the proapoptotic Bcl-2 family (By similarity).  Inhibits autophagy by interacting with host Beclin 1 (BECN1) (By similarity).
What are the official names of this protein?
Apoptosis regulator Bcl-2 homolog, LMH-5W.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Host mitochondrion. Host endoplasmic reticulum.
Protein: HIS4_BORA1
Sequence: MLLIPAIDLKDGRCVRLRQGDLDDVTVFSEDPAAIASNWLAQGARRLHLVDLNGAVAGKPKNEAPIKAILKAVGDDIPVQIGGGIRDLDTIERYLDAGISYVIIGTAAVKNPGFLHDACGAFPGQIIVGLDARDGKIATDGWSKLTRHDVLDLAKKFEDYGCEAIIYTDIGRDGMLSGVNVEATVRLAQHVRIPVYASGGIAGMADIEALCAVEADGVEGAILGRSIYEGALDFKVAQARADELTS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_STRPD
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQEYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFNKSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDAGREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDNQRHKIMVTTVGKILFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLDINVPFKKKNLGNIIAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVEEINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHPETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAVITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEGSIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSAEAVFTAEAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: COX3_BACSU
Sequence: MQVQEKFTAETFPASPEKVTLEGKNKFLGFWLFLGGETVLFASLFATFLALRNSNAGDPPTTEMFDVTLVFIATMLLLTSSLTSVYAMYHMKNFSFGKMQLWLGITILLGAGFLGLEIYEFKHYTHEFGFTITSSALGSAFYTLVGTHGAHVAFGLMWISTLMIRNAKRGLNLYTAPKFYVASLYWHFIDVVWVFIFTVVYLMGMVG
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Caa-3605 subunit 3, Cytochrome aa3 subunit 3, Cytochrome c oxidase polypeptide III, Oxidase aa(3) subunit 3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.