PharMolix/UniProtQA huggingface dataset:
Protein: LSPA_MYCS2
Sequence: MTDETSGPAEPVTDAPGDAESPAQPKRRLRLLLTVAAVVLFLDVVTKVLAVRLLTPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLVATGVVIGIIWMGRRLVSPWWALGLGLILGGATGNLVDRFFRSPGPLRGHVVDFFSVGWWPVFNVADPSVVGGAILLVALSLFGFDFDTVGRRRPGEDAEPSAGASDSTPEAPAADGPDKPAGPVGPEDAAEESKTVGHQAEPS
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS7_SPOFR
Sequence: MSTKIIKASAAEPDVFETSISQALVELETNSDLKAQLRELYITKAKEIELHNKKSIIIYVPMPKLKAFQKIQIRLVRELEKKFSGKHVVFIGDRKILPKPSHKTRVANKQKRPRSRTLTSVYDAILEDLVFPAEIVGKRIRIKLDGSQLIKVHLDKNQQTTIEHKVDTFQSVYKKLTGREVTFEFPEPYL
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity).  Required for rRNA maturation (By similarity).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
40S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
Protein: UVRC_ECOL6
Sequence: MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity).
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_BOVIN
Sequence: MAEEGIAAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  Subunit of the 40S ribosomal complex (By similarity).
What are the official names of this protein?
40S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC_MACGI
Sequence: MGDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLNGIFGRKTGQAPGFTYTDANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFAGIKKKGERADLIAYLKKATNE
What is the function of this protein?
Plays a role in apoptosis.  Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.  Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: MSCL_CHLAD
Sequence: MLNEFRTFINRGNVLDLAVGVIIGAAFTAIINSLVNDIINPLLGLLVGGRTDMSNYFLPLAGQTATTLAEARAAGPVLAYGSFLNAVINFLLVAFVIFLIVRTANRFNPKPAEPPALPQPTPSERLLAEIRDLLAQR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: C82X2_PAPSO
Sequence: MKSLMMNKLLFLQRITDSPSTTIISTFIVTIISIVFLYTVLLIRTTKNKQKIAAPKASGAWPFIGHLKLFMKQDTQFYRTLGTMSDKYGSVFTLRLGNQAILVVSNWEMVKECFTTNDKSFSNRPSTLSTKYMLNDTNSVVFSPYGTYWREMRKILVQKLLISNQRSEALKNLKTKEIDNSFVKLNDLCNNDVSGGGTKVRMDEWLADMMFNIIARITFGYQSGGGDAPGASTTSKNVERYKKTLDEMFVVLATRFAVSDIFPSLEFIDRLRGLVKDMKILGDELNSIAGCFIEEHRQKRRESLSSLLSLSNESVGDEQDFIDVLLSIMDQSRLPGDDPDFIIKIMILEAFAGGTDSLSATLTWVLSLLLNHPNVLKRAREEIDRHVENGKQVEVSDIPKLGYIDAIIKETMRLYPVGALSERYTTEECEVGRFNVPAGTRLLVNIWKIHRDPSVWENPSDFQPERFLCSDKVGVDLYGQNYELIPFGAGRRVCPAIVSSLQTMHYALARLIQGYEMKSASLDGKVNMEEMIAMSCHKMSPLEVIISPREPRRS
What is the function of this protein?
Cytochrome P450 involved in the biosynthesis of the benzylisoquinoline alkaloid noscapine (PubMed:25485687, PubMed:27378283, PubMed:29610307).  Converts (S)-1-hydroxy-N-methylcanadine to (13S,14R)-1,13-dihydroxy-N-methylcanadine (PubMed:25485687, PubMed:27378283).
What are the official names of this protein?
(S)-1-hydroxy-N-methylcanadine 13-hydroxylase CYP82X2, Cytochrome P450 82X2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ANF_HUMAN
Sequence: MSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRGPWDSSDRSALLKSKLRALLTAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRY
What is the function of this protein?
May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation.  In vivo promotes natriuresis.  In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
What are the official names of this protein?
Natriuretic peptides A, Atrial natriuretic factor prohormone, proANF, Atrial natriuretic peptide prohormone, preproANP, proANP, Atriopeptigen, Cardiodilatin, CDD, preproCDD-ANF.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
[Long-acting natriuretic peptide]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Vessel dilator]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Kaliuretic peptide]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Urodilatin]: Secreted. Note=Detected in urine (PubMed:2972874, PubMed:9794555, PubMed:8351194, PubMed:8779891). Not detected in blood (PubMed:8351194). Increased electrolytes, osmolality and intracellular cAMP levels increase peptide secretion/excretion (PubMed:9893117, PubMed:8853410, PubMed:8351194, PubMed:8779891). SUBCELLULAR LOCATION: [Atrial natriuretic peptide]: Secreted. Perikaryon. Cell projection. Note=Detected in blood (PubMed:8351194, PubMed:8779891, PubMed:7955907, PubMed:8653797, PubMed:15741263, PubMed:18835931, PubMed:2532366, PubMed:7984506). Detected in urine in one study (PubMed:8351194). However, in another study, was not detected in urine (PubMed:7984506). Detected in cytoplasmic bodies and neuronal processes of pyramidal neurons (layers II-VI) (PubMed:30534047). Increased secretion in response to the vasopressin AVP (By similarity). Likely to be secreted in response to an increase in atrial pressure or atrial stretch (PubMed:2532366). In kidney cells, secretion increases in response to activated guanylyl cyclases and increased intracellular cAMP levels (PubMed:9893117). Plasma levels increase 15 minutes after a high-salt meal, and decrease back to normal plasma levels 1 hr later (PubMed:8779891). SUBCELLULAR LOCATION: [Atriopeptin-3]: Secreted. Note=Detected in blood. Slight increase in secretion in response to the vasopressin AVP.
Protein: CU14B_LIMPO
Sequence: GYLYHPAYYYGAGASTQFKNQDAIGNYNFGYNEGHATGGTFRREFGDAFGNVKVGSYGLTDADGRRRIVTYKADASGFNANVHTNEPGTDSSKDPANTLVNKAVLPTTYYGGYYPGHYYGHYAPYHYGYY
What are the official names of this protein?
Cuticle protein 14 isoform b, LpCP14b.
Protein: IL17F_CALJA
Sequence: MTVKSLHVTAMVKYLLLLILGLAFLRETAAQRVPKEGQTFFQKPESCPSVPEGSLKLDLGIINANQRVPLSRNIERRSTSPWNYTVTWDPNRYPSEVVQAQCRHLGCVNAQGKEDIFMNSVPIQQETLVLRRKHQGCSVSFQLEKLLVTVGCTCVKPLIHHVH
What is the function of this protein?
Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity.  IL17A-IL17F signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter through SEFIR domains.  This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.  IL17A-IL17F is primarily involved in host defense against extracellular bacteria and fungi by inducing neutrophilic inflammation.  As signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites.  Stimulates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers.  IL17F homodimer can signal via IL17RC homodimeric receptor complex, triggering downstream activation of TRAF6 and NF-kappa-B signaling pathway.  Via IL17RC induces transcriptional activation of IL33, a potent cytokine that stimulates group 2 innate lymphoid cells and adaptive T-helper 2 cells involved in pulmonary allergic response to fungi.  Likely via IL17RC, promotes sympathetic innervation of peripheral organs by coordinating the communication between gamma-delta T cells and parenchymal cells.  Stimulates sympathetic innervation of thermogenic adipose tissue by driving TGFB1 expression.  Regulates the composition of intestinal microbiota and immune tolerance by inducing antimicrobial proteins that specifically control the growth of commensal Firmicutes and Bacteroidetes.
What are the official names of this protein?
Interleukin-17F, IL-17F.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU2C_PROM9
Sequence: MPNEIFTINLNAQAIIPEAFILLGIVGTLLVDLAGEKTASKWAPIICYLSIGSSLFSLALQWSNPVNSAFLGSFNSDNLAIAFRAIIALSTLVSLLISWRYTEQSGSPIGEFAAIVLSATLGAMLLCGSTDLISIFISLETLSVASYLLSGYLKRDPRSSEAALKYLLVGSAAAAVYLYGSSFLYGLSGSTNLATIGLEIINKPSFITSLALVFVLSTVAFKIAAVPFHQWTPDVYEGSPTPVVAFLSVGSKTAGFAFAIRILSTTFSSFDEEWKLLFTILAILSMALGNVVALAQTSMKRMLAYSSIGQAGFVMIGIVSGTQDGLSATVLYLAAYLFMNLGAFSCVILFSLRTGSDRILDYSGLYQKDPLITLGLSLCLLSLGGLPPMLGFFGKIYLFFAGWANHQYLLVIIGLVTSVISIYYYISVIKMMVVKEPQEASEIVKSYPEINWGIVGMPPLRVALYTCVAVTALGGILSNPLFKLANTAVSETPFLQEIIAMANNIS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PAN3_ASHGO
Sequence: MMMNKSKTDWAKDTPCKNITIYGYCKYENDGCIFNHGKPLSTSSNTGGAAAGSAEDSAASGGVTVGNTGKSTFNAKTATSFTPSVAIPDFNNIPSFTPERIVSSPAGDGATAFTPSFNPYGSDSFNPSANVSGPGSAVFAAASGNAGASATAAPRSQSVHVGTGGYLPLAGTAFPTVYPPSHSILQYHLYAPDPPPHLQVPLKANERTPETLFIPNNLREHLLKRNLSALQVFPSDGNLPDIVGDYFGLVPLEFHNRQTGKGRYLGHQNSLYKVFSNFDGKVYIIRRIHDVKTTDVGQISLPFRKWQKVSCPNVVKVKDAFTTLAFGDSSLCVVHDYYPQSNSLYETHVANYTVVPVTQKYLWSYLVQLSNALNEVHRHGLSMNNISLDKVIVTGDPGRIKVGDSAVHDILAFDEGRDIAKEQQADYSAVGALLMDLAQRMLGTRDQPLDSMDIDPLFKRVLAYLLSDEKKTIAEFTALFSHKMLDIISSSQTYSEYIEQHLSRELENGRLFRLMCKLNFIFGRMESSMDIHWSEAGDKFPIILFYDYVFHQVDENGKSVMDLTHVLRCLNKLDTGVSEKIILVTPDEMNCIIISYKELKDSIDSTFRSMTQ
What is the function of this protein?
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.  PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex subunit PAN3, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. PAN3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_POLSJ
Sequence: MRVSASVKKICRNCKIIRRKGVVRVICTDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: BIOD_XYLFA
Sequence: MSLSAFYVTGTDTGIGKTFVSCILLHMLRGRGQRAVGMKPVASGCTYSDTGWRNEDALALQAASDPTPAYDLINPYALPAAVAPEIAAIEAGVTVALEPLSAAFTQLRAQADVVVVEGVGGWATPLNATIDQATLVRALEIPVVLVVGLRLGCLNHARLSTTAIMADGLRCIGWIANTIDPHMARIEENLALLRQRLPIPYWGHLPHIPPGINPATLAARLHPQGD
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTB7_MYCTU
Sequence: MAEDVRAEIVASVLEVVVNEGDQIDKGDVVVLLESMKMEIPVLAEAAGTVSKVAVSVGDVIQAGDLIAVIS
What are the official names of this protein?
Biotinylated protein TB7.3.
Protein: HSP11_SOYBN
Sequence: MSLIPSFFGGRRSSVFDPFSLDVWDPFKDFPFPSSLSAENSAFVSTRVDWKETPEAHVFKADIPGLKKEEVKLEIQDGRVLQISGERNVEKEDKNDTWHRVERSSGKLVRRFRLPENAKVDQVKASMENGVLTVTVPKEEIKKPDVKAIDISG
What are the official names of this protein?
17.3 kDa class I heat shock protein, HSP 17.3.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y965_MYCTU
Sequence: MRVNRPQCARVPYSAESLVRVEASWYGRTLRAIPEVLSQVGYQQADHGESLLTSHHCCLGAAEGARPGWVGSSAGALSGLLDSWAEASTAHAARIGDHSYGMHLAAVGFAEMEEHNAAALAAVYPTGGGSARCDGVDVS
What are the official names of this protein?
Uncharacterized protein Rv0965c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2798c.
Protein: RR4A_CYACA
Sequence: MSRYTGPKIRIIRRLGELPALTTKKVKNNYPPGREWSTNEELSEYAIRLQEKQKIRFNYGINEKQLRRYVKKAKKSRGSTGSYLLNLLEMRLDNIVLRAGLAPTIAASRQLVSHKHIEVNNKIVNIPSFQCSIGDTIHVKKSNKSRQLIDLNSRRDTTKFFPKYLEVNKDNMGARVVKTMDKQDVNLTINELLVVEFYSRKG
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PTPB_STAAU
Sequence: MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpB, Phosphotyrosine phosphatase B, PTPase B.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: RS10_GEOSL
Sequence: MPSQKIRIRLKAFDHKLLDQSVGEIVDTAKRTGARVAGPIPLPTVINKYCVLRGPHVDKKSREQFEIRTHKRLIDILDPTQQTVDALMKLDLSAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DAPB_AERS4
Sequence: MDNPIRVAVMGCNGRMGKVLLEAITNADGVVVGAALERPGSAVIGLDAGELNGLGKLGVMISDSLDKVRDEFDLIIDFTRPEVTLANLAFALAHQKQMVIGTTGFDDAGKAALKEAGKQIGIVFASNYSVGVNLVFKLLEQAAKVMGDYTDIEIIEGHHRHKVDAPSGTALSMGEVVAKTLGRDLKECAVYGREGITGERDRNTIGFATIRAGDMVGEHTVMFADIGERVEISHKASSRLTFANGAVRAGKWLGQQGAGLYDMQDVLSLK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSIC_SALTI
Sequence: MLNYVLKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLIAGPEADAQVIALVRQQLGLDQPLHVQFWHYITHVLQGDFGTSMVSRRPVSEEIASRFLPTLWLTITSMIWAVLFGMAIGIAAAVWRNRWPDRVGMTLAVTGISFPAFALGMLLMQIFSVDLGWLPTVGADSWQHYILPSLTLGAAVASVMARFTRSSFVDVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVDMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIRYK
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABZ_CLOPS
Sequence: MMNINEIKEILPHRYPFLLVDKVEEITESKVVAYKNVTINEPFFQGHFPDYPVMPGVLIVEALAQAGAIALLNKEEFKGKTPFFAGIDKVRFKKQVLPGDTLRLEVEIIKLRGSIGFGKATATVDGKIACSGEIMFAIG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPQI_MYCTU
Sequence: MAFPRTLAILAAAAALVVACSHGGTPTGSSTTSGASPATPVAVPVPRSCAEPAGIPALLSPRDKLAQLLVVGVRDAADAQAVVTNYHVGGILIGSDTDLTIFDGALAEIVAGGGPLPLAVSVDEEGGRVSRLRSLIGGTGPSARELAQTRTVQQVRDLARDRGRQMRKLGITIDFAPVVDVTDAPDDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGVLPVLKHFPGHGRGSGDSHNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPGLTGSEPASLSKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQAGADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPGCGR
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptidoglycan fragments.  Acts as a regulator for GlcNAc-MurNAc levels by cleaving disaccharides and allowing the breakdown of MurNAc.
What are the official names of this protein?
Beta-hexosaminidase LpqI, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor; Periplasmic side.
Protein: ENO_ECOK1
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: YWSB_BACSU
Sequence: MNKPTKLFSTLALAAGMTAAAAGGAGTIHAQQPETTVSIDDLYSYPIDSYLVSAEALNVRTKPSASSQKADTLHLGDSLKLISFSNADWAKVKYKNGKTGFVSTHYIVKAATTVKTKTKTKVYTSADGKSIKTLPADTSVSFLGWSKTNKGGFDFDWVFVDYGGTTGYMKTKDLHMTK
What are the official names of this protein?
Cell wall-binding protein YwsB.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Released into the extracellular medium in a strain lacking the WprA protease.