PharMolix/UniProtQA huggingface dataset:
Protein: ZN714_HUMAN
Sequence: MNVMLENYKNLVFLAGIAVSKQDPITSLEQEKEPWNMKICEMVDESPAMCSSFTRDLWPEQDIKDSFQQVILRRHGKCEHENLQLRKGSANVVECKVYKKGYELNQCLTTTQSKIFPCDKYIKVFHKIFNSNRHKTRHTGEKPFKCKKCDESFCMLLHLHQHKRIHIRENSYQCEECDKVFKRFSTLTRHKRVHTGEKPFKCEECGKAFKHSSTLTTHKMIHTGEKPYRCEECGKAFYHSSHLTTHKVIHTGEKPFKCEECGKAFNHPSALTTHKFIHVKEKPYKCEECDKAFNRFSYLTKHKIIHSGEKSYKCEQCGKGFNWSSTLTKHKRIHTGEKPYKCEECGKAFNVSSHLTTHKMIHTGEKPYKCEECGKAFNHSSKLTIHKIIHTGEKPYKCEECGKAFNQSSNLTKHKIIHTGEKLYKCEECGKAFNRSSNLTTHKRIHTGEKPYKCEECGKAFNRSSNLTKHNIIHTGEKSYKCEECGKAFNQSSTLTKHRKIQQGMVAHACNPNTLRGLGEQIARSGVQDQPGQHGKTPSLLKIQKFAGCGGRRL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 714.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMM_PSEF5
Sequence: MTKKYFGTDGIRGRVGEFPITPDFMLKLGWAAGMAFRSMGACRVLVGKDTRISGYMFESALEAGLSAAGADVMLLGPMPTPAIAYLTRTFHAEAGIVISASHNPHDDNGIKFFSGEGTKLPDEVELMIEELLDAPMTVVESSKLGKVSRINDASGRYIEFCKSSVPSSTSFAGLKVVLDCAHGATYKVAPSVFRELGAQVTVLSAQPNGLNINENCGSTHMSQLQAAVLAEHADLGIAFDGDGDRVLMVDQTGAIVDGDELLFIIARDLHERDKLQGGVVGTLMSNLGLELALADLGIPFVRANVGDRYVIAELLERNWLVGGENSGHIVCFRHATTGDAIIAALQVLMALKARGESLAQSRQGLRKCPQVLVNVRFGGGENPVEHPAVKEACERVTAAMAGRGRVLLRKSGTEPLVRVMVEGDDEAQVRAYAEELAKLVAEVSA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PRPE_OCEIH
Sequence: MKIDIIGDVHGCLEELEELLFKLGYQIKNGTYQHSNNRQIVFVGDITDRGPDSIKVIKLVYQLVKEKLAYYIPGNHCNKLYRFFQGNKVMEKHGLETTTAEYRSLSKEKQNNIKHKFIELYERSPLYLHLKNINVIIAHAGIPEHLIGKKDKRTKTFVLYGDITGEFDTTGKPIRRDWAKHYHGDSWIVYGHTPVLEPRVVNHTINIDTGCVFGNKLTAYRFPEKEFVSVASRQPFIAEKFTDFNVSNEH
What is the function of this protein?
Asymmetrically hydrolyzes Ap4p to yield AMP and ATP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical], Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the PrpE family.
Protein: AMY_CLOAB
Sequence: MSKRSKLLKRRMLSLSVICVLIGYGPVFNPVRSQAKVMTYSSENRELPENTKDGVMLHAFDWSFNNIKKELPSIAAAGYKAVQVSPVQGTKSNSTNSSDWWLLYQPTNQAIGNAQLGSYDDFKSLCSEAKNYGISIVVDVVMNHMANNGNDDEVASEVDPSFKDPSLYHHNGQCTDWNNRQDVTQEGIGMPDLNTQSSAVQSKAITFLNQCVDAGATGFRFDAAKHIETDLGLDANKSWSGNYWENVLGSLHNKSNLYIYGEVLQDGKVDNISAYESFMNVEASAYDGSLRGAIKSGDLTNAQGMGGLDSNKCVDMLETHDEYEHNESKDLTDWQRKAGWAIAASRAGSVPLFFDRPTGNIGSEGDALWKDSDVVAVNEFHNAMAGQNEYLRLQNNNKAMIIERGSKGAVIVNEGDSFNLNTPTNLEDGNYDNHGSATDSLTVSQGRMTGTVPANSIIVIYNKNSNPGSDRVTLSEQAAKAGDSVTITYDAGTTALKDASNVNLYWGYDGFSAATSKAMTSLGDNKWQTTITVPKEVTKNVNFSFTDGTSWDNNNGANWNIPLASNYLPHAGYKVDYDSSNLVSGNNFTIYYNGNLANSSNVSLHWGVNGWSNMQNLAMVKDSNGFWEATIAIPASSNTLNFCFTNGSSWDNNNNNNWTLNTWSSVPKVQVTPAPEACKQISVYYNGSLASSASNITLHWGCNGFTSPQDINMVKQADGRWLANITLPSGCYNVNMAFKDQSGTWDNNNSNNYNFSSTNN
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: RL23_ZYMMO
Sequence: MAKSQDGVAIRHYDVVLGPHITEKSTMVSEFNAVVFKVAADATKPAIKEAVEALFGVSVKSVNTVITKGKTKKWKGRPYRRSDVKKAIVTLAEGQSIDVTTGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: FTSB_YERPA
Sequence: MGKLTLLLLVLLGWLQYSLWLGKNGIHDFVRVKEDVAAQEANNSTLKARNDQLFAEIDDLNGGQEAIEERARNELGMIKPGESFYRLVPDQSRRNAGTPSTQNNAQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: G6PC1_CANLF
Sequence: MEKGMDVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLREAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVMDTDYYSNTSVPLIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFRGRKRPTYRFRCLNILLWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFRHIQSIYNASLKKYFLITFFLFSFAIGFYLLLKGLGVDLLWTLEKARRWCERPEWVHIDTTPFASLLKNVGTLFGLGVTLNSSMYRESCKGKLSKWFPFRLSCIVVSLILLHLFDSLKPPSQTELIFYTLSFCKSAAVPLASVSLIPYCLARVFDQPDKKSL
What is the function of this protein?
Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.  Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis.  Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
What are the official names of this protein?
Glucose-6-phosphatase catalytic subunit 1, Glucose-6-phosphatase, G-6-Pase, G6Pase.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphatase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DSBB_BURP0
Sequence: MNNLTLSLRRERRLLVLLALVCLALLAGALYLQYVKNEDPCPLCIIQRYFFVLIAVFAFIGAGMASGAGVAVTEALIVLSAAAGVGTAARHLYVQLNPGFSCGFDALQPVVDSLPPARWLPGVFKVAGLCETVYPPIFGILLPGWALIAFVLIAVPVAVSLLRHRGRLR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YGFZ_SALEP
Sequence: MAFISFPPRHPSSSARLPLTLIALDDWALSTITGVDSEKYIQGQVTADVSQMTEQQHLLAAHCDAKGKMWSTLRLFRERDGFAWIERRSVREAQLTELKKYAVFSKVVIAPDDERVLLGVAGFQARAALANVFSELPNSENQVVRDGASTLLWFEHPAERFLLVTDVATANMLTEKLHGEAELNNSQQWLALDIEAGIPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGKASRVPEAGEDLELQMGENWRRTGAILAATQLDDGQLLVQAVMNNDLEAESVFRVRDDANTLHIVPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_SALCH
Sequence: MSQLDLNALNELPKVDRVLALAEINAQLETLSAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLATQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_CHLAA
Sequence: MYVHHLFLRDFRNYRRLDLALAPATTLFYGPNAAGKTSLLEAIFYLATTRSPRLSSDRELVRWDAVGEAGTPPFARIAADVERRIGPVRLEVLVQRRADDDGQPLNGAQKLVRIDKRPARAIDLIGQLRVVLFTPTDLTLVDGPPAERRRYLDITLSQLDPHYVRTLAHYQKILLQRNSLLRAWREQRRVPRHVDAELAYWDQELAAAGGYLLAERLRAIVELNDLAGPLYQEMSGGEDRLQIEYAASCDLGTARDAGGLAERLLLAFAAQRSDELARGQTLCGPHRDDLIFTVAGINLGRYGSRGQQRSIALALKIGEAGLMRRRSGEAPVLLLDDVLSELDAQRRAHLLALIHHPDQQTLLTATDLSDFSADFLAAVRRYRVEDGQVFAG
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_CLOBJ
Sequence: MYNCAIILAAGKGKRMKSSMPKVVHKVCGKEMVNHVIDNVRKANIKDVNLVIGKGSKTVKEHTKDRNLTYSMQEEQLGTGHAVICAEEFLKDKKGTVAIFTGDAPLITNETIQQLFEFHNSGKYAATLISSTVQDPTGYGRIIREASGEVKKIVEHKDCNEEELKVNEINSGMYCFDIEVLLNSLKNLNNDNSQGEYYLTDVIEITKKSGDKVGAIVVPYEEIMGVNSRVQLSEAEIVMRKRINHKHMVNGVTFIDCESTYIDVDVEIGNDTIIYPGCVIQGNTTIKEECTLYSNSRICNSVIGSGVIVENSVILESHVGEGTTVGPFAYIRPETKIGKSARIGDFVEIKKSTIGDNTKVSHLTYIGDAEVGSKCNFGCGTVVVNYDGQKKQKTIIGNNAFIGCNTNLISPVKVNNNTYIAAGSTITKEVPEGSLAIARSKQINKEGWLDKKGLLKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_STAA1
Sequence: MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDIEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNC_ECOLI
Sequence: MFEIHPVKKVSVVIPVYNEQESLPELIRRTTTACESLGKEYEILLIDDGSSDNSAHMLVEASQAENSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYGCMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREFGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Polymyxin resistance protein PmrF, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBP2_YEAST
Sequence: MPNEDNELQKAIENHHNQLLNQDKENADRNGSVIEDLPLYGTSINQQSTPGDVDDGKHLLYPDIATNLPLKTSDRLLDDILCDTIFLNSTDPKVMQKGLQSRGILKESMLSYSTFRSSIRPNCLGSLTDQVVFQTKSEYDSISCPKYNKIHVFQAVIFNPSLAEQQISTFDDIVKIPIYHLKVSVKVRQELERLKKHVGVTQFHSLDHLHEYDRVDLSTFDSSDPNLLDYGIYVSDDTNKLILIEIFKPEFNSPEEHESFTADAIKKRYNAMCVKNESLDKSETPSQVDCFYTLFKIFKGPLTRKSKAEPTKTIDSGNLALNTHLNPEWLTSKYGFQASSEIDEETNEIFTEYVPPDMVDYVNDLETRKIRESFVRKCLQLIFWGQLSTSLLAPNSPLKNTKSVKGMSSLQTSFSTLPWFHLLGESRARILLNSNEQTHSPLDAEPHFINLSVSHYYTDRDIIRNYESLSSLDPENIGLYFDALTYIANRKGAYQLIAYCGKQDIIGQEALENALLMFKINPKECNISELNEATLLSIYKYETSNKSQVTSNHLTNLKNALRLLAKYTKSDKLKFYVDHEPYRALSQAYDTLSIDESVDEDIIKTAYSVKINDSPGLKLDCDRALYTIAISKRSLDLFNFLTEECPQFSNYYGPEKLDYQEALKLLQVNENASDETILKIFKQKWFDENVYEPDQFLILRAALTKISIERNSTLITNFLLTGTIDPNSLPPENWPTGINNIGNTCYLNSLLQYYFSIAPLRRYVLEYQKTVENFNDHLSNSGHIRRIGGREISRGEVERSIQFIYQLRNLFYAMVHTRERCVTPSKELAYLAFAPSNVEVEFEVEGNKVVDQTGVLSDSKKETTDDAFTTKIKDTSLIDLEMEDGLNGDVGTDANRKKNESNDAEVSENEDTTGLTSPTRVAKISSDQLENALEMGRQQDVTECIGNVLFQIESGSEPIRYDEDNEQYDLVKQLFYGTTKQSIVPLSATNKVRTKVERFLSLLINIGDHPKDIYDAFDSYFKDEYLTMEEYGDVIRTVAVTTFPTILQVQIQRVYYDRERLMPFKSIEPLPFKEVIYMDRYADTENPLLLAKKKETEEMKQKLKVMKNRQRELLSRDDSGLTRKDAFLESIKLLESDTIKKTPLKIEAANDVIKTLRNNVQNIDNELMKLYNDINSLEEKISHQFDDFKEYGYSLFSVFIHRGEASYGHYWIYIKDRNRNGIWRKYNDETISEVQEEEVFNFNEGNTATPYFLVYVKQGQEGDIEPLKRILK
What is the function of this protein?
Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety in natural or engineered linear fusion proteins, irrespective of their size or the presence of an N-terminal extension to ubiquitin (PubMed:15933713).  Hydrolyzes polyubiquitinated 'Lys-63' polyubiquitin chains in RPO21, producing mono-ubiquitinated RNA polymerase II (PubMed:19920177).  Removes ubiquitin chains that initiate proteolysis of FZO1 and inhibit mitochondrial fusion (PubMed:23317502).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 2, Deubiquitinating enzyme 2, Ubiquitin thioesterase 2, Ubiquitin-specific-processing protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: HIS5_MANSM
Sequence: MIIIDTGCANLSSVKFAFDRLNIKAEISRDIATIKSADKLLLPGVGTAMAAMKILQDRNLIETIQNATQPMLGICLGMQLMTEYSSEGNVPTLSLMSGHTDLIPNTGLPLPHMGWNKVRYEQDHPLFAGIEQDSHFYFVHSYAVLPNEHTIATSDYGVPFSAALGCKNFYGVQFHPERSGKNGAQLLKNFVENL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGFA_CANLF
Sequence: MGRWAWGPSLCPLPGMALLLLLLLLLVPHGAQPQAGGNLTEPPEPNATVTPGTPMIPVTSVTPVTPATSAPEAQGPRGRGLTPPPRAAPSSSSPGDPVLTVDGQPCRFPFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYCVQAPVSREGPAALDSCASSPCLNGGSCSHTQDPGSYHCTCPMAFTGRNCDTEKCFDETRYEHLEAGDRWARVSQGQVEQCECAGGQIRCEGTRHTACLSSPCLNGGTCHLIVATGTTVCSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACESLARIPSLTTAVLLSQAEPAPVGRQTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSNSPRRESVLVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFNPSDHDLVLIRLKKKGDRCAIRSQFVQPICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLNKPGVYTRVAKYVDWIKDRIWPSKRPSDPS
What is the function of this protein?
Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
What are the official names of this protein?
Hepatocyte growth factor activator, HGF activator, HGFA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted as an inactive single- chain precursor and is then activated to a heterodimeric form.
Protein: RPOB_THIDA
Sequence: MAYTFTEKKRLRKSFASRTNTLPVPFLLATQLESYRAFLQEGRSRDERLNEGLQAAFTSIFPIESHSKNARLEYVSYQLGEPVFDIKECQQRGLTYCAPLRAKVRLVIMDKEASKPTIKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDRGKTHSSGKLLFSARVIPYRGSWLDFEFDAKDILFFRVDRRRKMPVTILLKALGYTPESILDAFFNKDTFYINTLGIQFELVPERLRGEIARFDICGKDDKVIVAKDKRITAKHIRELDAAGVKKWAVPGEFVVGRVLAHDVVDKDTGELVARANDEITEELLKKLAAAGIDKFQTLYTNDLDHGAFISQTLRTDDTTDEYAAKVAIYRMMRPGEPPTEDAVNALFVNLFFSDERYDLSAVGRMKFNRRIGRDELTGTGTLSTEDIVAVIKILVELRNGRGEIDDIDHLGNRRVRSVGELAENQFRAGLVRVERAVRERLSQAESDNLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALFARTNWYGFIETPYRKVVDNKVTDEIEYLSAIEESKYVIAQANAELDAKGKFKDDLVSCRFKNEFTLSAPDRIEYMDVAPAQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPFVGTGIERTAAVDSGTVVIAHRGGRVDYVDAGRIVIRVHDEEARAGEVGVDIYSLIKYTRSNQNTNINQRPLVKVGDVIARGDVIADGASTDMGELALGQNMLVAFMPWNGYNFEDSILINEKVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAERQLARLDESGIIAIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLKVPSGMSGVVIDVQVFTREGIERDKRAQSIIDTQLAEYKKDLTDRMRIVEDDTFARLEKLLHLKVVNGGPKKLAKGSKISKEYLDSLNRHDWFDIRLADDEASRQVESLKDSLTQKRVEFDAMFEEKKQKLTAGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPFMADGRPVDIVLNPLGVPSRMNIGQILETHLGWASKGLGEKIGQMMAAQTKSVVKELRHFFKEVYNQSGKAEDIDNFTDDEILELGQNLQKGVPFASPVFDGATEEEIRRMLALAGLPEGGQVTLYDGRTGEAFDRQVTVGYKHVLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGDHKIEAGMPESFNVLVKEIRSLGIDIDLERY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: LUXS_BACAH
Sequence: MPSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLLAFNLRKYIDRYPHFDIIDISPMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPAANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RT09_BOVIN
Sequence: MAAPSVSCGAAVPYRLFLAGRVSFAREQGLWKAAASGLQTGTRCQILRLKHSPAVTTTKNVAALRRESYTVDFIKKQIEEFNIGKRHLANMMGEDPETFTQEDVDRAITYLFPSGLFEKRARPIMKHPEEIFPKQRAVQWGEDGRPFHFLFYTGKQSYYSLMHEAYGKVLHAEERQDQLRAKGLFSEKSKSKDLIGSRWLIKEELEEMLVEKLSDQDYAQFIRLLERLSALPCDAAEEEFVGRFRRTVTVQSKKHLIEPLQYDEQGMAFSTGQGKRKTANAEAVVYGHGSGKIEINGVDYLLYFPVTQDREQLMFPFHFLDRLGKHDVTCTVSGGGRSSQAGAIRLAMSRALCSFITEDEVEWMRQAGLLTTDPRVRERKKPGQEGARRKFTWKKR
What are the official names of this protein?
28S ribosomal protein S9, mitochondrial, MRP-S9, S9mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LIPA_PARBD
Sequence: MAASARGLRTLQSAHSSTTVPRLQLAVSRCYATTTSPDPPITNSSNSSNSSNSTPTPKQRITAFKDKLNAGPSFSDFVSGGGGGGASNDRVPLDPAEAYALKTALVGPPGRKKQIIRLPSWLKTPIPDTPNYRRIKSDLRGLNLHTVCEEARCPNISDCWGGSSKSAATATIMLMGDTCTRGCRFCSVKTSRTPPPLDPHEPENTAEALSRWGLGYVVMTSVDRDDLADGGARHVVETVRKVKQKAPGILLECLTGDYAGDLEMVALVATSGLDVFAHNVETVEALTPFVRDRRATFQQSLRVLKAAKEARPELITKTSIMLGLGETETQLWETLRALRAVDVDVVTFGQYMRPTKRHMAVHEYVRPEVFDLWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRRGEGADGGDGGNSTRREDVERLVAGGVVR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SDF2A_DROMO
Sequence: MLRQVLSSTSVRRLLVSPTRCMSGKQNVPDKIEYSTPPEIIDYEESPHLPVPEYPIRPDEPLETRKQRLLYQSRKRGMLENDLLLSTFVAKYLKDFDAEETAQYDQLINGVSNDWDIYYWATNTKPTPPEYDTDVMKLLKQHVKNTERVQRIRQPDL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2-A, mitochondrial, SDH assembly factor 2-A, SDHAF2-A.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: C85CB_DANRE
Sequence: MAKHCPNDDLSKIPDEELVRWSKEDLIRRLRRVDGEKMSLMLEHSNMMKDVNRSLQVHLHEIRNLKEINQKLQDDNQELRELCCFLDDDRQKGKKLSREWQRFGKFTASSVWKEVSTYQQKLKELEINQENVLRENAELKDIILMLDEDRNGAGSRSSIDSQSSLSNLNGGSGTVRDVGDGSSTSSGGSAGSPDHHHNHIHKTVEAKIGTVRRSMDDLSAPHHHRSIPAGLNDASSNYIRQLETKVRILEDNNNKLLSQPCSRYSLSKLSMKYNPGDLRALRKGMTLYHSESQLSSLPQRQEALLNGTGRLQTSESSPSTGFISSAQKPEAVVHAMKVLEVHDNLEKQLPEESEEDLSEKEKAIVREMCNVVWRKLGDATGTKPSLRQQLSGNQFKAPL
What is the function of this protein?
May play a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity).  May play an important role in cortical development, especially in the maintenance of radial glia (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 85C-B.
What is the protein family that this protein belongs to?
Belongs to the CCDC85 family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell junction, adherens junction.
Protein: 3MGA_HAEIN
Sequence: MTTRCPWVGEQSIYIDYHDKEWGKPEFDSQKLFEKICLEGQQAGLSWITVLKKRESYREAFHQFDPKKIAKMTALDIDACMQNSGLIRHRAKLEAIVKNAKAYLAMEKCGENFSDFIWSFVNHKPIVNDVPDLRSVPTKTEVSKALSKALKKRGFVFIGETTCYAFMQSMGLVDDHLNDCPCKTS
What is the function of this protein?
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions.
What are the official names of this protein?
DNA-3-methyladenine glycosylase, 3-methyladenine-DNA glycosidase, TAG.
Protein: E310_ADE12
Sequence: MVTVLLIFLCLPVIFSSSTFAAVSDLDPECLAPFAVYLIFTFVTATCVCSIITLLITSLQFFDYYYVRIVYRRHHPRYQNPQIAALLQLQP
What is the function of this protein?
Down-regulates the EGF receptor.
What are the official names of this protein?
Early E3B 10.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3B family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.