PharMolix/UniProtQA huggingface dataset:
Protein: TUSA_CITK8
Sequence: MTDLFSSPDHTLDAQGLRCPEPVMMVRKTVRNMQTGETLLIIADDPATTRDIPGFCTFMEHELMAKETDSLPYRYLLRKKH
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFS1_SCHPO
Sequence: MSKMGSLMLSRARCLLELRSALFFVKRESQDINNVRQSLGVYGRSFMTSSRMDKPSMSNKPREQMYGLGNMTAVQEPIPENSLKTVTLDQAQTAASTVTGLHPIYMDFQATSPLDYRVLDSMLPFFTGIYGNPHSRTHAYGWEAEKAVENARQEIASVINADPREIIFTSGATESNNAILKGVARFYKSRKKHLVSVQTEHKCVLDSLRALQEEGFEVTFLPVQTNGLINLDELRDAIRPDTVCVSVMAVNNEIGVCQPLEEIGKICRQKKVFFHSDAAQGYGKIDIDVNRMNIDLMSISAHKIYGPKGIGAAYVRRRPRVRLEPLISGGGQERGLRSGTLAPSQVVGFGTAARICKEEMKYDYAHISKLSQRLIDGLLAIPYTSLNGDPKSRYPGCVNISFNYVEGESLLMGLKNIALSSGSACTSASLEPSYVLRAIGQSDENAHSSIRFGIGRFTTEAEIDYAIENVSRQVSFLRNMSPLWDLVQEGVDLSTIEWSQH
What is the function of this protein?
Catalyzes the removal of elemental sulfur from cysteine to produce alanine.  It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters.  Plays a role in both tRNA-processing and mitochondrial metabolism.  Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.
What are the official names of this protein?
Probable cysteine desulfurase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYT_STRP6
Sequence: MIKITFPDGAVREFESGVTTFDIAESLSKSLAKKALAGKFNDQLIDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGFYYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELINEHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLERYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNCPHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQIQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALDEMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKTLRDRGVRADVDDRNEKMQYKIRTSQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTESVEEFVENILADIARKSRPDAQA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PY2CR_BACCZ
Sequence: MLVISANEQRKLVNMNEVIAYAALALQEFSAERTITPIRTSLPFANEQNTALIMPSVAEGLEALGLKVVTVVPENKKIGKKTINGIVMLSDFQTGEPLALLEGSYLTMIRTGALSGVATKHLARHNAKTLCIIGTGEQAKGIAEAVFAVRDIEKVMLYNRTEEKAYAFAQYIQEKFGKPAYVYANANEAISEADIIVTTTNASTPVFSEKLQKGVHINAVGSFRPNMQELPSHAIANANKVVVESKEAALEETGDLQVPVREGLFEASDIHAELGQIISGEKAGRESDEEITVFKSVGLAVVDIIVAKYLYEKAVERGVGERIEF
What is the function of this protein?
Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor.  May be involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline.
What are the official names of this protein?
Delta(1)-pyrroline-2-carboxylate reductase, Pyr2C reductase, Proline ketimine reductase.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
Protein: RS7_ORITI
Sequence: MSRRCTEVKRKSLPSNKYQSISAATSNQIMLASKLINKLTHHGNKELVEKMLDKIIQHIKHKYKADGFEVLESACNNVKPSLQVESLRIGGATYQVPSPVNELRSYTLAIKWIINSAANRTFEKSMWQKIAEELYEASNGRGGAVKKKDDNHKMAEANQAFSHLITKRRSRGN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RLMH_ACIBS
Sequence: MKIRILTIGQKMPAWVLTGFEDYFKRIQPFVQTQVIKLPMAKRGKNDSEADILKYCQIEGESILNALKPNETLIALEVGGRELSTEKLADTMKQWMLEGNDVALAIGGPDGLSDQVRKAAAWHWSLSKLTMPHPLVRILLIEQLYRAMSINHNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_RICCN
Sequence: MQTIEQQIANVIEESLTDMGFELVLVKFKGVNPKVVEILIDSLNSEKISVEDCTKASRTISAILDVEDLIEAAYSLEVASSGLERPLVKFENYNRFLEREVKIKLKELLNGKTRYQGKIIKAENNKIYLKCEEQEVLIDYDLIKNANLVLTEEVFKKLLKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_BURTA
Sequence: MPLNREDKQAVVAEVAAQVAKAQTVVLAEYRGIAVGDLTTLRAKAREQKVYLRVLKNTLARRAVEGTPFAPLAEQMTGPLIYGISEDAIAAAKVVNDFSKSNDKLVIKAGSYDGKVMDKAGVQALASIPSREELLSKLLFVMQAPVSGFARALAALAEKKQAEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: TRMD_ESCF3
Sequence: MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKKEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAZA2_ARTJA
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDVGNGKFLDPKNRICFKFDHLRKEATDPRPYEAENAIESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: RSMA_BACP2
Sequence: MNKDIATPIRTKEILKKYGFSFKKSLGQNFLIDTNILDRIVDHAEVTDETGVIEIGPGIGALTEQLAKRAKKVTAFEIDQRLLPILNDTLSPYDNVTIIHQDVLKADVGKVIEENFADCKEVMVVANLPYYVTTPIIMKLLEENLPLKGIVVMLQKEVADRMAAIPSSKEYNSLSIAVQYYTEAKTVMVVPKTVFVPQPNVDSAVIKLTVRETPAVSVENDEFFFQLIRASFGQRRKTLMNNLMNNLPDGKQHKAIIEEALQTADIDGKRRGESLSIEEFARLSNVLQKALF
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK3_BLACR
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, BlaCr-PVK-3, PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTR10_ARATH
Sequence: MAIAEEEAALIEDSVSDSVDHRGLPAGKSSTGGWRSAWYIIGVEVGERFAYFGIGSNLITYLTGPLGQSTATAAVNVNTWSGTASILPVLGAFIADAYLGRYRTIVVASLIYILGLGLLTLSSILILMGLSEQRQHNRNASAKPFFWVNILFFCSLYLVAIGQGGHKPCVQAFGADQFDVGDPKERISRGSFFNWWFLSLSAGITLSIIVVVYVQDNVNWALGFGIPCLFMVMALALFLFGRKTYRYPRGDREGKNNAFARIGRVFLVAFKNRKLKLTHSGQLEVGSYKKCKGQLEFLAKALLPGEGGVEPCSSRDVEDAMALVRLIPIWITSVVSTIPYAQYATFFTKQGVTVDRKILPGFEIPPASFQALIGLSIFISVPTYERVFLPLARLITKKPSGITMLQRIGAGMVLSSLNMVVAALVEMKRLETAKEHGLVDRPDATIPMSIWWFVPQYLLLGMIDVFSLVGTQEFFYDQVPTELRSIGLALSLSAMGLASFLSGFLITVINWATGKNGGDSWFNTNLNRAHVDYFYWLLAAFTAIGFLAFLLLSRLYVYRRVDQV
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 5.16, AtNPF5.16.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYE_BUCAP
Sequence: MKVKTRFAPSPTGNLHIGSIRTALYSWLFARHYHGKFILRIEDTDFERFDSKSVESILYGLKWLGLNWDEGPYFQSKRLERYKEVIKMMLESGNAYKCFCSVKELEDERIRQVSKGKKPRYSGICRNLHYRNYIANENYVVRFKNPISGQVTFEDKIRGKITFQNEELDDLVIQRSNGIPTYNFCVVIDDLDMNITHVIRGEDHINNTPRQINILKSLNAKIPIYAHVSMIFNEDGHKFSKRQDALNILEYCKDGFLPEALLNYVIRLGWSCGNQEIFSISEMKELFDLRKISKSSSAVSMKKLFWLNKYYINNLPLSYISNLLKDHMNHEKINLKNGPDLESVLTLLKNRHHTLKEIAQSSRYFYEEFANFDKSAADEYLIPENHFILKNLYKNIKKISIWSNETLSSLIKNDCIKLKITLRKISMLLRVVLTGNIFSPSISSVIFLIGKEKTLLRLKKAILFIDNKIKNINN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_THEMA
Sequence: MKEKVVLAYSGGLDTSVILKWLCEKGFDVIAYVANVGQKDDFVAIKEKALKTGASKVYVEDLRREFVTDYIFTALLGNAMYEGRYLLGTAIARPLIAKRQVEIAEKEGAQYVAHGATGKGNDQVRFELTYAALNPNLKVISPWKDPEFLAKFKGRTDLINYAMEKGIPIKVSKKRPYSEDENLMHISHEAGKLEDPAHIPDEDVFTWTVSPKDAPDEETLLEIHFENGIPVKVVNLKDGTEKTDPLELFEYLNEVGAKNGVGRLDMVENRFIGIKSRGVYETPGATILWIAHRDLEGITMDKEVMHLRDMLAPKFAELIYNGFWFSPEMEFLLAAFRKAQENVTGKVTVSIYKGNVMPVARYSPYSLYNPELSSMDVEGGFDATDSKGFINIHALRLKVHQLVKKGYQR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR7G_ECOLX
Sequence: MNNIPPIPQLGIYVSKIDPTLRITVTDVDIVDGEDDSPDDELFYLVHWIEGEDESDMTAMGFELDPVEWQAFVESEQLVFERESVHGFNPRKFKLGKDSGFSHED
What are the official names of this protein?
Protein ORFg in retron Ec67.
Protein: FRMD7_HUMAN
Sequence: MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEIVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDFHEETDRKHLAQTRYLPNQDCLEGKIMHFHQKHIGRSPAESDILLLDIARKLDMYGIRPHPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGRKGRLKSLPFERKHYPSQYHERQCRSSPDLLSDVSKQVEDLRLAYGGGYYQNVNGVHASEPVLESRRRNSALEVTFATELEHSKPEADPTLLHQSQSSSSFPFIYMDPVFNTEPNPNPDPRDIFSERSSLSSFQTSCKFSGNHMSIYSGLTSKVRPAKQLTYTDVPYIPCTGQQVGIMPPQVFFYVDKPPQVPRWSPIRAEERTSPHSYVEPTAMKPAERSPRNIRMKSFQQDLQVLQEAIARTSGRSNINVGLEEEDPNLEDAFVCNIQEQTPKRSQSQSDMKTIRFPFGSEFRPLGPCPALSHKADLFTDMFAEQELPAVLMDQSTAERYVASESSDSESEILKPDYYALYGKEIRSPMARIRLSSGSLQLDEEDEDAYFNTPTAEDRTSLKPCNYFLA
What is the function of this protein?
Plays a role in neurite development, may be through the activation of the GTPase RAC1.  Plays a role in the control of eye movement and gaze stability.
What are the official names of this protein?
FERM domain-containing protein 7.
What are the subcellular locations of this protein?
Cell projection, neuron projection. Cell projection, growth cone. Note=In undifferentiated neurons, located in the actin-rich regions of the cell body. In differentiated neurons, located in the actin-rich regions of the cell body and primary neurite processes but is almost absent from secondary extensions arising from the primary neurite. Also found at the actin-rich distal end of growth cones (By similarity).
Protein: IAP_ASFP4
Sequence: MFPKINTIDPYISLRLFEVKPKYVGYSSVDARNQSFAIHDIKNYEKFSNAGLFYTSPTEITCYCCGMKFCNWLYEKHPLQVHGFWSRNCGFMRATLGIIGLKKMIDSYNDYYNNEVFVKHKNRVYTHKKLEDMGFSKPFMQFILANAFIPPYRKYIHKIILNDRYFTFKFAAHLLSFHKVNLDNQTTYCMTCGIEPIKKDENFCNACKTLNYKHYKTLNFSVKL
What is the function of this protein?
Prevent apoptosis of host cell by inhibiting caspase-3/CASP3 activation to promote the viral replication.  Induces also the activation of host NF-kappaB.
What are the official names of this protein?
Inhibitor of apoptosis protein, IAP.
What is the protein family that this protein belongs to?
Belongs to the asfivirus IAP family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Probably accumulates in the perinuclear cytoplasmic viral factories. Found in association with viral nucleoid.
Protein: HSM3_KLULA
Sequence: MTDVTKDIDNLADALLTMEISPEINDLMEKLALNLTSSNNLPVDVKHLLTSIKTYLTQSSSEMLDYNLLLEVLDAVVGLCPFEDVLKVFSVDDLITALKSGDKALTETVCQVIAAASPRDIFAGTPLLDEMLKLYFCESTVVAIVNALEKTLGILVTNQLNRRRILENNLPVLISVKDCKNSTTFCRFLDLIKILSASVTFEEFRKDIFIIDNMVTNKMMENDILVFIHICQYYIELLTISLTEDGKEWVIRYVKPSFEIFGEAFSRREELFDVGHFAKSYLLTLFSKISYLDDKSYIQLLEAQFFPLYPDKQYLDEFLTVLDPSYIAKVHLDLLKEKALRAGNVHMFVNLIKDEDCFVQLKDEINSKTLNDMPYIEKMLLLDGLTLTSYGIQHLTRNMPSVMNSIIDSGNQVTEKLSFDLRLRVFENLLEANPQELSVWLIPLQSEYANILNGRRGRFSSGQLADDYL
What is the function of this protein?
Involved in DNA mismatch repair in slow-growing cells.  Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC) (By similarity).
What are the official names of this protein?
DNA mismatch repair protein HSM3.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5B/HSM3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOC1_DICDI
Sequence: MDHLGYSGGISRVGIQHNRYSGQFSDRYSQYSESEYDPSETTHSESDSENHHHSNIPILEYPSFLSQSNDNVSNGPSNNTLSSSATSLGNNDGDEDLENVINNYLSFEKDVDILTERLGKTLSTLETEMIVGVLDSGVGVNEVISQLGDKDGTHLTGVTAWIEYYNKQLQDMKKYIEHIEGKNNKMEIVSRNQKLLYSELNNLIGLMTLSDNTISTLTAPQFNDTKGLKMAIEAAEDLKRALTTKLKSGMDNMMAVKDQRKVFETYKISFARKVAALVENIFKTTDKEIGKHVITTTSQTPGEEKFPDYLEYYDLLRKFKPLVNWLKEMDHEKLIPLIVSYIKAFRRIYESDIKLFFSTIQQSLEKESKDQNDFFSSSSSSKKSIDSLNNNTSTSTPSKNSSSSSSSSSGKDGIKKRKINRLFKYALSCLEIYIMTKQNFVMDFFLYQDPPRLAGQRNHHSNSSGGGSGSNKDGKDRKDKKSSKKDKKDKKDKKDKKDKKKKDPDSSSSPSLDNDKPIDSNSPKSPNNAVNGSLSSTEESSPPPPPPPPPKESPDAPLDLILSAMFNGVVPELINMVEKADQVNPFYLLTMLLETELYIDAHSRKDSHHSSYFVKILAEVQKSIKTLFNKFLEVQVDAIKSTQTSLKRCGVLPHFRNFHIFVKELQKYKSESDTGSSTLLIESSYKKIILELFNWLDGLVEKLPEDKKYKFISKLENHYFFYLKLQELNINCLTQHKDTSQSIFKENLEIYVNFLIDLKFKPLIEYYTKMDELLLTLPPSDIQFQQSHSKQQFKKIVEKFKTENIEKGLLKALGNVQKNITKDSQLILVIWERLEEVFIEKYEHFQDITSDCYNQTMPVSSDQIKGIFGTVYKKNPNKH
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 1, Exocyst complex component Sec3.
What is the protein family that this protein belongs to?
Belongs to the SEC3 family.
What are the subcellular locations of this protein?
Midbody, Midbody ring.
Protein: ISPD_PARMW
Sequence: MHLLIAAAGSGRRMGADRNKLLLPLAGKPVIAWTLKAALAAEHIQWIGVVGQEIDREPILDLVRDANKPVTWIQGGSTRQESVLRGLAGLPEAAEQVLIHDGARCLAEPALFDRCAMALASGQALIAATPVTDTIKRVDADGVITDTPDRSELWAAQTPQGFQVDQLRHGHAEAEANGWTVTDDASLYERLGWPVQVLDAGPSNIKVTTPFDLNVAEAVLALRQQD
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: DEF_ALKEH
Sequence: MAILDILVYPDPRLREVAAPVAQVDDDIRRLADDMLETMYDAQGIGLAATQVGVNQRVVVMDLAEEGARQPLVLINPEILDREGAATGQEGCLSIPGFYEDVERAERIRFRALDREGRPWEQEAEGLMAVCVQHEIDHLDGKLFVDYLSELKRKRIRRKLEKLVRQGRVNVGGQTGRA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: CHDC_STAA3
Sequence: MSQAAETLDGWYSLHLFYAVDWASLRIVPKDERDALVTEFQSFLENTATVRSSKSGDQAIYNITGQKADLLLWFLRPEMKSLNHIENEFNKLRIADFLIPTYSYVSVIELSNYLAGKSDEDPYENPHIKARLYPELPHSDYICFYPMNKRRNETYNWYMLTMEERQKLMYDHGMIGRKYAGKIKQFITGSVGFDDFEWGVTLFSDDVLQFKKIVYEMRFDETTARYGEFGSFFVGHIINTNEFDQFFAIS
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: RL25_CAMLR
Sequence: MLEGIVRESIGRKAAKALKRDGYLIANIYGKGLENINAAFKINEFIKEVRKKTTLAFDVKVGGKVLNVVVVDYQKDPVTAELKHVDLKVAQKGVISKYMVPVKIVGTAMGLKNKGVLIQSKRRLKVKCAAENLPNYFELDVTKLDVGDALLVRDVVVPEGVTMVDADRVAVVGVEKAR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: VIRB4_BARHE
Sequence: MSMMKRESLPEDYIPYIRHINQHVIALNSRCLMTVMVVEGVNFDTADIDQLNSLHNQLNTLLKNIADERVALYSHIIRRRETIYPESQFFSSFAATLDEKYKKKMVSQELYRNDLFVSLLWNPASDKTEQLASFFQRLAKAKKTQSEPDQEAIRKIEELSQDLIEGLESYGARLLSVYAHGGILFSEQSEFLHQLVGGRRERIPLTFGTIASTIYSDRVIFGKETIEIRHESNERFAGMFGWKEYPSKTRPGMTDGLLTAPFEFILTQSFVFKSKAAASVIMGRKQNQMINAADRASSQIEALDEALDDLESNRFVLGEHHLSLAVFANHPKALAEYLSKARAHLTNGGAVIAREDLGLEAAWWAQLPGNFSYRARSGAITSRNFAALSPFHSFPIGKLEGNVWGTAVALLKTQAGSPYYFNFHYGDLGNTFVCGPSGSGKTVIVNFLLAQLQKHNPTMVFFDKDQGAEIFVRAGGGKYKPLKNGQPTGIAPLKGMEYTEKNKVFLRNWVLKLVTAEGQTVTEEERQDIAKAIDALGNLPHAQRSLSALQLFFDNTSKEGIAIRLQRWLKGNDLGWVFDNDQDDLNLDSQFIGYDMTDFLDNEEIRRPLMMYLFNRILDLIDGRRIIIVIDEFWKALEDDSFKAFAQDRLKTIRKQNGMMLFATQSPKDALNSTIAHTIIEQCPTQIFFPNQKANYKDYVEDFKLTEREFELIQSELSRESRRFLIKQGQSSVVAELNLRGMNDEIAVLSGTTKNIELVNQIISEYGADPDIWLPIFHQRRENQ
What is the function of this protein?
The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function.  VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a pro-inflammatory activation by nuclear factor NF-kappa-B, inhibition of early and late events of apoptosis, leading to an increased cell survival, and, at high infection doses, a cytostatic or cytotoxic effect, which interfers with a potent VirB-independent mitogenic activity.  These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G.  Altogether with VirB11, may be implicated in providing the energy, via hydrolysis of ATP, for the assembly of secretion system and substrate transport.
What are the official names of this protein?
Type IV secretion system protein virB4.
What is the protein family that this protein belongs to?
Belongs to the TrbE/VirB4 family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: RS16_BIFA0
Sequence: MATKIRLKRMGKKFYAVYRVVVMDSRTKRDGRAIEEIGLYNPNTQPSTIEIKSDRAQYWLGVGAQPTDQVLNLLKITGDWQKFKGLKGAEGTLKTAAAKPEAAVLVEEAENKAQKLKAAKAEAAAKAAEAETPAEVQHDDEKVELADVEESAPESV
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL35_PROMT
Sequence: MPKLKTRKAAAKRFKATGTGKFMRRRAFHNHLLDHKSPKLKRHLKTKAVVDERDAENVRLMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.