PharMolix/UniProtQA huggingface dataset:
Protein: PYRH_POLSJ
Sequence: MPAYKRILLKLSGEALMGDDAFGINHATIVRMVEEIAEVTRMGVQVAVVIGGGNIFRGVAGGSVGMDRATADYMGMLATVMNALALGDTMDKAGLIARVMSAIGIERVVEPYVRPKALQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAEIVLKATKVDGVYTADPKKDPRATRYTNITFDEAMGKNLEVMDATAFALCRDQKLPIKVFSIFKHGALKRVVQGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_HAHCH
Sequence: MTDQVNRPKGVTSVALIAHDNKKADLIAWVEKNSVKLNKCTVYATGTTGKLIAEKTGVDVKRCHSGPLGGDQQIGALISEGKVDLLIFFWDPLEPMPHDPDIKALLRLATLWNVPSACNSATADFLVNSNLFEEFLPQRPDFDSYLSRDVPGN
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: FSV1_SCHPO
Sequence: MSNLLLIIDSVSQKIRDRRKLEEFGQNPDEEIESSLKDVRQELQKLNEEQSRLEKNAQIPEYRVRESEAFLIRMQRRLESAEEEFEKQRRASSIPADGTSAFSANPQVASTNNKLTPLPSLQKTTSSSEGSDIEMEAMYPVDGNDPDPINVNVLAQMHQQMLNEQEESLGGIEASVQRQKRMGYAMNTELSEQNVLLDNMNNDADRIERRFDHAKNRLNKVSRKAKQYPRCFIILLLCALLLLVASI
What is the function of this protein?
Involved in vesicle-mediated protein transport between the Golgi and the vacuole.
What are the official names of this protein?
Syntaxin-like protein fsv1.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Note=Associated with the Golgi and prevacuolar membrane.
Protein: LAG3_MOUSE
Sequence: MREDLLLGFLLLGLLWEAPVVSSGPGKELPVVWAQEGAPVHLPCSLKSPNLDPNFLRRGGVIWQHQPDSGQPTPIPALDLHQGMPSPRQPAPGRYTVLSVAPGGLRSGRQPLHPHVQLEERGLQRGDFSLWLRPALRTDAGEYHATVRLPNRALSCSLRLRVGQASMIASPSGVLKLSDWVLLNCSFSRPDRPVSVHWFQGQNRVPVYNSPRHFLAETFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVLGLEPVAPLTVYAAEGSRVELPCHLPPGVGTPSLLIAKWTPPGGGPELPVAGKSGNFTLHLEAVGLAQAGTYTCSIHLQGQQLNATVTLAVITVTPKSFGLPGSRGKLLCEVTPASGKERFVWRPLNNLSRSCPGPVLEIQEARLLAERWQCQLYEGQRLLGATVYAAESSSGAHSARRISGDLKGGHLVLVLILGALSLFLLVAGAFGFHWWRKQLLLRRFSALEHGIQPFPAQRKIEELERELETEMGQEPEPEPEPQLEPEPRQL
What is the function of this protein?
May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response.
What are the official names of this protein?
Lymphocyte activation gene 3 protein, LAG-3, Activation-induced cytidine deaminase-linked autoimmunity protein, Aida.
What is the protein family that this protein belongs to?
Belongs to the LAG3 family.
What are the subcellular locations of this protein?
[Lymphocyte activation gene 3 protein]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Secreted lymphocyte activation gene 3 protein]: Secreted. Note=Produced following cleavage of the main chain.
Protein: PG045_VACCP
Sequence: MLSMFMCNNIVDYVDDIDNGIVQDIEDEASNNVDHDYVYPLPENMVYRFDKSTNILDYLSTERDHVMMAVRYYMSKQRLDDLYRQLPTKTRSYIDIINIYCDKVSNDYNRDMNIMYDMASTKSFTVYDINNEVNTILMDNKGLGVRLATISFITELGRRCMNPVKTIKMFTLLSHTICDDCFVDYITDISPPDNTIPNTSTREYLK
What is the function of this protein?
Plays a role in evading host innate immune response by inhibiting host inflammasome activation.  Interacts with and inhibits NLR-mediated interleukin-1 beta/IL1B production in infected cells.  At the host mitochondria outer membrane, interacts with the BH3 domain of host BAK and prevents BAK from binding active BAX.  In turn, host apoptosis is inhibited.
What are the official names of this protein?
Apoptosis regulator OPG045, Protein F1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG045 family.
Protein: DRC4_HUMAN
Sequence: MAPKKKGKKGKAKGTPIVDGLAPEDMSKEQVEEHVSRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTELHEVEERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPAALTLVSRKLEDVLESKNSTIKDLQYELAQVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGTPT
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.  Plays an important role in the assembly of the N-DRC linker (By similarity).  Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement.  Required for proper motile cilia functioning (PubMed:26387594, PubMed:27120127, PubMed:27472056).  Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner (By similarity).
What are the official names of this protein?
Dynein regulatory complex subunit 4, Growth arrest-specific protein 11, GAS-11, Growth arrest-specific protein 8, GAS-8.
What is the protein family that this protein belongs to?
Belongs to the DRC4 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Golgi apparatus. Cell projection, cilium. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Associates with microtubules (PubMed:10969087). Localized to the cytoplasm of round spermatids, the tails of elongating spermatids, and mature spermatid tail bundles protruding into the lumen, and in the flagellum of epididymal spermatozoa (By similarity).
Protein: TGT_ECOLI
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TREM1_PIG
Sequence: MRSARLGRLLWMLFITEIQAATELPEEKYILAEGETLNVNCPVTVGVYSNSRKAWQKLNRNGKFQTLAITERVSGQVSKVQVGKIFLTDEPSEGMLHVQMTNVQAEDSGLYRCVIYQPPKDPIILFYPVRLVVTNYSSGTPASAETPTQSCSPTTTLPPTTTTNRHRPRPRTVRTVTQFLTDFTTSLSSPGLKVTLTNVTDITRDTEISLILPAVCGLLSKSLVFIVLFVVTRMSFTP
What is the function of this protein?
Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses.  Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12.  In turn, initiates a SYK-mediated cascade of tyrosine phosphorylation, activating multiple downstream mediators such as BTK, MAPK1, MAPK3 or phospholipase C-gamma.  This cascade promotes the neutrophil- and macrophage-mediated release of pro-inflammatory cytokines and/or chemokines, as well as their migration and thereby amplifies inflammatory responses that are triggered by bacterial and fungal infections.  By also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute and chronic inflammatory diseases of different etiologies including septic shock and atherosclerosis.
What are the official names of this protein?
Triggering receptor expressed on myeloid cells 1, TREM-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Recruited to lipid rafts when activated.
Protein: TRMD_XANOP
Sequence: MRIDVISLFPEFIAQCAAFGVVGRAQERGLLELQGWNPREHAQGNYRRVDDRPFGGGPGMVMLIEPLRACLDAVQAADARPAPVIYFSPQGRRLTQMLARELAQLPRMVLLCGRYEGVDERFLAQAVDMEISIGDYVLSGGELGAAVVVDVVTRLQEGVLNDAESAAQDSFEGPQGLLDCPHYSHPSSHAWGDVPEVLRSGNHAAIARWRRQQSLGRTWLRRPDLLDEAGLDKHDRRLLEEFRRELAKGDEESGCTPSP
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_MAGMM
Sequence: MQKGEKLYEGKAKVLFATDDPNMLIQYFKDDATAFNGIKKGTIADKGVVNSLISTRIYHILEKVGIPTHLEELLSPREQLVHKVEILPIEVVIRNRVAGSLARRLGIEEGTELARPLVEFYYKNDELDDPMVTIDHAEVFGWAKHREIEEMIEMSLRINDILIGFFANIGIDLIDYKLEYGRLAVSPSTLVLADEISPDGCRLWDMETGEKLDKDRFRRDLGGVEEAYQEVARRMGLEVPGR
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: OBP_PHOSU
Sequence: NDYAELEGKWDTIAIAADNDAKIKEEGPLRLYVRELYCNEDCSEMEVTFYVNANNQCSKTTVIGYKQADGTYRTQFEGDNRFQPVYATPENIVFTSKNVDRAGQETNLIFVVGKSQPLTPEQHEKLVEFAHENNIPEENIHNVLATDTCPK
What is the function of this protein?
May act as a pheromone.
What are the official names of this protein?
Odorant-binding protein, Lipocalin.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LLDD_YERPA
Sequence: MIISASTDYRAAAQRKLPPFLFHYIDGGAYNEQTLRRNTADLADIALRQRVLKNMSELSLETQLFGETQAMPVVLGPVGLSGMYARRGEVQAARAADKKGIPFTLSTLSVCPIEEVAPAIARPMWFQLYVLKDRGFMRNALTRAQAAGVKTLVFTVDMPVPGARYRDAHSGMSGPNAAARRLLQAIAHPQWAWDVGLNGKPHDLGNISAYLGKPTTLEDYMGWIATNFDPSISWKDLEWVREFWQGPMIIKGILDPEDAKDAVKFGADGIVVSNHGGRQLDGVLSTARALPAIADAVKGDITILADSGIRTGLDVVRMIALGADSVLLGRAFVYALATAGEAGVINLLTLIEQEMRVAMTLTGAKRIADINRDSLAVSERG
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PRMA_SHIF8
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHF2_MOUSE
Sequence: MATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKSTLKKKRTWHKHGPGPTPDVKPVQNGSQLFIKELRSRTFPSAEDVVSRVPGSQLTVGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKIFYLIRPASANISLYERWRSASNHSEMFFADQVDRCYKCTVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHEDELPEHFRPSQLIKDLAKEIRLSENASKTVRPEVNAAASSDEVCDGDREKEEPPSPVETTPPRSLLEKVSKKKTSKTVKMPKPSKIPKPPKSPKPPKTLKLKDGSKKKGKKCKESASPTIPNLDLLEAHTKEALTKMEPPKKGKTPKSVLSVPNKDTVHTQNDMERLEIREQTKSKSEAKWKYKNSKPDSLLKMEEEQRLEKSPLAGNKDKFSFSFSNRKLLGSKALRPPSSPGVFGALQSFKEDKAKPVRDEYEYVSDDGELKIDEFPIRRKKSAPKRDLSFLLDKKEALLMPTSKPKLDSAVYKSDDSSDEGSLHIDTDTKPGRNAKVKKESGSSAAGILDLLQASEEVGALEYNPNSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGTGQAKGGSLAAHGARKIGGGNKGTGKRLLKRTAKNSVDLEDYEEQDHLDACFKDSDYVYPSLESDEDNPVFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKNRKKKNTKRKPAPNTASPSISTSASASTGTTSASTTPASTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFSGSQAGRASQPMAPGVFLTQRRPSASSPNNTAAKGKRTKKGMATAKQRLGKILKIHRNGKLLL
What is the function of this protein?
Lysine demethylase that demethylates both histones and non-histone proteins (PubMed:22921934).  Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B.  Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes.  The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver.  PHF2 is recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA (By similarity).  Involved in the activation of toll-like receptor 4 (TLR4)-target inflammatory genes in macrophages by catalyzing the demethylation of trimethylated histone H4 lysine 20 (H4K20me3) at the gene promoters (PubMed:22921934).
What are the official names of this protein?
Lysine-specific demethylase PHF2, GRC5, PHD finger protein 2.
What is the protein family that this protein belongs to?
Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome, centromere, kinetochore.
Protein: HXC5A_TAKRU
Sequence: MFSFDLSERRSGRYEGVNGIFTCPVPTTSTKREEMKTSLRGSAETLLPSGPQITMVSSSTTVDASGLSYGGNTLLGLGADRDPERSAKLGGNKSQESERSAENAQTVKRNPQVTERPDSEQQPQIYPWMTKLHMNHESEGKRSRTSYTRYQTLELEKEFHFNRYLSRRRRIEIAHNLCLNERQIKIWFQNRRMKWKKDSKIKVKE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C5a.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1547_METJA
Sequence: MSKVFGILLYGSYAKNEYTKRSDIDICLVGVDRNTYLEILGKLGNKYDIKIFEELPLYIKMEIIKNHKVIFGDELELSEHFYKFRKIWRDMEKRIRENQFNSVREKVMLRRRFNAKKEEILG
What is the function of this protein?
Probable antitoxin component of a putative type VII toxin-antitoxin (TA) system.  Neutralizes cognate toxic MJ1548 by di-AMPylation.
What are the official names of this protein?
Putative protein adenylyltransferase MJ1547, Putative antitoxin MJ1547.
What is the protein family that this protein belongs to?
Belongs to the MntA antitoxin family.
Protein: TATA_SHESM
Sequence: MGGISIWQLLIIALIVVLLFGTKKLRSLGGDLGGAVKGFKNAMSSEEDKKALEDAEAAKPVQTAQTAQPTQQATEKKPESNKEQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RPOC_SALPA
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECETLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERIYRAGLASLHARVKVRITEYEKDENGEFVAHTSLKDTTVGRAILWMIVPKGLPFSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQTMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEQQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGILMTPVIEGGDVKEPLRDRVLGRVTAEDVLNPGTADILVPRNTLLHEQWCDLLEANSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVMAKGDGEQVAGGETVANWDPHTMPVITEVSGFIRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTTGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEIAGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIESAGSSDFLEGEQVEYSRVKIANRELEANGKVGATFSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEQLATPQVTAEDASASLAELLNAGLGGSDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: FENR_FRACC
Sequence: MLIVGAGPAGLYGAYYAGFRGMSVALMDSLPEAGGQVTAMYPEKVIYDIAGLPAVRGRELIDALLIQANQFSPTYLLGQQAAELAHKPDAVVVTSSQGLRVRAKVVVITGGLGTFAPRPLPTGTAHLGRGLVYFVPKLDVHTGQDVIVVGGGDSAFDWALALEPIARSVTLVHRRDRFRAHMSTVERVEASSVEILTFTEVAMVHGEEWIEKVELVQTRTGDRHVRPAQAVVAALGFTADLGPLTRWNLTIDKRHIVVDPTMATGVERIFAAGDITEYPGKVRLIATGFGEAATAVNNAAPLVDPSAKIFPGHSSDDGTGG
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RT07_CAEBR
Sequence: MSKKLANFAQKRWISCSSNSFNMYDPRVFREPVSNVQELRKPLDVDDERNFLFLKAMKSDATPVFYRDSVIDKLIRVCTKDGEKETSRKNVLSALEIIKRRQYKAWTKANDEEKKSIELDPFVIARKGIKNCHPLMKLQGVTRGGTTYQVPFPIEEPEAEFRAMKMMRDICRVRAKHGETHFKDILATELLAASQNEGSTITAKQELHKTCEANRAYAHYRA
What are the official names of this protein?
28S ribosomal protein S7, mitochondrial, MRP-S7, S7mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YNHG_ECOLI
Sequence: MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTVQEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNLAELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLERGIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIKALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQFKDNKAVDQKLVDKALYRRAGYPVSVSSGATPAASNAPSVESAQNGEPEQGNMLRVTQ
What is the function of this protein?
Responsible, at least in part, for generating a meso-diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link.
What are the official names of this protein?
Probable L,D-transpeptidase YnhG.
What is the protein family that this protein belongs to?
Belongs to the YkuD family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VC03_SWPVK
Sequence: MSDCIFVFQIPFIVYSKLDQWIFGNILCKIMSVLYYVGFFSNMFIITLMSIDRYFAIVHPIKRQPYRTKRIGILMCCSAWLLSLILSSPVSKLYENIPHMSKDIYQCTLTNENDSIIAFIKRLMQIEITILGFLIPIIIFVYCYYRIFSTVVRLRNRRKYKSIKIVLMIVVCSLICWIPLYIVLMIATIVSLYTSNIFRHLCLYLNLAYAITFSETISLARCCINPIIYTLIGEHVRSRISSICSCIYRDNRIRKKLFSRKSSSSSNII
What are the official names of this protein?
G-protein coupled receptor homolog C3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: AROB_HYPNA
Sequence: MKTSSPLETVRVELGARAYDILVGHGALSELGPRLSQMLKRPRAFVLTDETVARHHKDALEAAVKSAGIRLDWLSLPPGEKTKSFSQLEGVLDWLLAGGADRGDTLIAFGGGVIGDMGGLAASLMKRGMGFVQVPTTLLAQVDSSVGGKTAVNTPRGKNLIGAFYQPRLVIADTALLATLPARELKAGYAEIVKYGLINDAAFFDWLAVNGQKVLALEPEAARYAVARSCAAKAAIVAEDETETGVRQLLNLGHTFGHAFEAANEYRENLLHGEAVALGMALAFRYGAASGITPAADAARVTEVLGASGLPVSLEGFDPARFAADRLAALMQQDKKARAGRVPLILARGIGAAYVHPDADLASVERFLASELA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DES_TOBAC
Sequence: MSSFLVSSNNLPEREIPGDYGFPIISAIKDRYDYFYKQGEDVWFHSKAEKYNSTVVKINMAPGPFTSNDYKLVAFLDANSFVYMFDNSLIDKTDTLGGTFKPGKEYYGGYRPVAFVDTSDPNHAALKNYILTSFAKRHNLFIPLFRNSVSDHLFQNLEKQVSDQGKSDFNALLPNMTFGFIFRLLCDQTNPSDTVLGAQGPEHLRKWLFPQLIPSLSARKLPSFIEDLLFHNFLIPFGLVKSDYNKLVDAFSKNAGSMLDEAEKLGIKREEAVHNILFLVGINMFAGLNAFFPHLIRFVGEAGPTLHARLAKEIRTAIKEEGGAVTLSAINKMSLVESIVYETLRLRPPVPLQYGKAKKDFMVQSHDASYMIKKGQFLVGYQPMASRDPKIFDKPDDFIPDRFMGEGVKMLKHVLWSNGRETENPAPDNKQCAGKDLVHLLGRLMLVEFFLRYDTFTVEITPLFRAPNVAIKTLTKAT
What is the function of this protein?
Strictly inducible cytochrome P450 involved in the biosynthesis of the anti-fungal toxins colneleic acid and colnelenic acid.  Can use (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoic acid (9-HPOD) and (10E,12Z,15Z)-(9S)-9-hydroperoxyoctadeca-10,12,15-trienoic acid (9-HPOT) as substrates but has a very low activity with the corresponding 13-hydroperoxides.
What are the official names of this protein?
9-divinyl ether synthase, NtDES1, Colneleate synthase, Cytochrome P450 74D3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family. 9-divinyl ether synthase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SSRP_BACC7
Sequence: MPKGSGKVIAQNKKAFHDYFIEETYEAGLVLQGTEIKSIRAGRVNLKDAFARVHNGEVWVHNMHISTYEQGNRFNHDPLRTRKLLLHKKEIDKLAGAAKETGYALVPLKIYLKNGFAKMALGLAKGKKQYDKRHDLKEKEAKREIARAFRDRQKM
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.