PharMolix/UniProtQA huggingface dataset:
Protein: RL15_BURTA
Sequence: MELNNLKPAEGAKHAKRRVGRGIGSGLGKTAGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKRGFTSLTKEFVGEVRLGDLEKLPVDEVDLLALKQAGLVGELTKSAKIIATGELKRKIVVKGLGATKGARAAIEAAGGSFAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: UNG_MYCBT
Sequence: MTARPLSELVERGWAAALEPVADQVAHMGQFLRAEIAAGRRYLPAGSNVLRAFTFPFDNVRVLIVGQDPYPTPGHAVGLSFSVAPDVRPWPRSLANIFDEYTADLGYPLPSNGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEAVTECAIRALAARAAPLVAILWGRDASTLKPMLAAGNCVAIESPHPSPLSASRGFFGSRPFSRANELLVGMGAEPIDWRLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_GEOSL
Sequence: MQERYIPKNVEGKWQEIWEENKTFTVTEDPSKPKYYLLEMFPYPSGRIHMGHVRNYSIGDVVGRFKRMRGFNVLHPMGWDAFGMPAENAAIKHGSHPAKWTYENIDYMRSQLKKMGLSYDWGRELATCDVDYYKWEQKMFLEMYEKGLVYKKSSFVNWCPACETVLANEQVEDGCCWRCDSDVTQKELDQWFFRITRYAEELLEDTWNLPGWPERVLVMQRNWIGKSFGCEIDFPVEGKVEKVKVFTTRQDTLYGATFMSLAPEHPQALELTTPERRAEVEAFIDKVKKTDKIKRTAEDFEKEGVFTGAYCINPVTNLRMPVYLANFVLLDYGTGAVMAVPTHDQRDFEFARTYDLPLQVVIQPEGETLDPAAMTAAYTEVGTMVNSGPFNGMKSDEAKEKIADYLEQEGVGTKTVNYRLRDWGISRQRYWGNPIPVINCDICGVVPVPDKDLPVVLPMDAEFTGEGGNPLARVESFVNVTCPQCGAEARRETDTMDTFVQSSWYFLRYCCPDFACGPIDRARAGYWMPVDQYIGGIEHAVLHLLYSRFFTKALRDLGYVTVAEPFKNLLTQGMVIKDGAKMSKSKGNVVDPDALIERYGADTARLFTLFAAPPEKDLDWSDQGVEGSFRFLNRVWRLVFEVLPFIGSAGKPDPAALGDGARDLRRTVHKTIRKVTDDLDERFHFNTAISAVMELVNAIQSFEPKNAPENAPVLREAVESVVQLLAPFVPHVAEELWESLGHQGGVEASGWPSYDPEATVEEELLIVVQVNGKLRGKVTVAVDAGEEQVKAAAFADDKVKPWLDGKQIRKAIYVPGKLLNIVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK16_SOLLC
Sequence: MLSPKRTRFRKQHRGRMKGISYRGNRISFGKYALQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTLRPAETRMGSGKGSPEYWVAVVKPGRILYEMGGVTENIARRAISLAASKMPIRTQFIIS
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LS14B_HUMAN
Sequence: MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMAPYGPLAASSLLSQQYAASLGLGAGFPSIPVGKSPMVEQAVQTGSADNLNAKKLLPGKGTTGTQLNGRQAQPSSKTASDVVQPAAVQAQGQVNDENRRPQRRRSGNRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAEKGEEKDLAVVTQSAEAPAEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGRGNGTTRRNPTSHRAGTGRV
What is the function of this protein?
Required for oocyte meiotic maturation.  May be involved in the storage of translationally inactive mRNAs and protect them from degradation (By similarity).  Plays a role in control of mRNA translation (By similarity).
What are the official names of this protein?
Protein LSM14 homolog B, RNA-associated protein 55B, hRAP55B.
What is the protein family that this protein belongs to?
Belongs to the LSM14 family.
Protein: G3P_ZYGRO
Sequence: MVNVSVNGFGRIGRLVTRIAISRKDINLVAINDPFISTDYAAYMFKYDSTHGRFDGEVSHDKDHIILNGKKVAVFNEKDPAALPWGKLGVDVAIDSTGIFKEMDSANKHIEAGAKKVVITAPSGSAPMYVMGVNEETYTPDQKIVSNASCTTNCLAPLAKVIHNEFGIKEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPSLQGKLTGMAFRVPTVDVSVVDLTVNLAKETSYDEIKAALKKASEGSMKGILGYTEDDVVSSDFLGDAHSSIVDAAAGIQLTPTFVKLVSWYDNEFGYSTRVVDLVEHVAKSA
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_MYCGA
Sequence: MRIRNIRDAHLKINKAKNIIGVDNLKTKLDPKKFNALEIGSGKGGFIYQKAITNPGINYFGIEKNATVILKMINKSELLEQLTNLFIVHDDFALIDHEFPNACFDQIYLNFSDPWPKKRHAKKRLVDLAFLNKYQRILKADGIIEFKTDNDQLFNYAIEMINSLEQIKIIAYTNDLHSLDSSDALLKNNVITEYEQRFINLKKNINKIVFKFI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RSMB_ECOLI
Sequence: MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRINRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVHALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLVYATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAB_SHIDS
Sequence: MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHMAGEITVTGNKYVVGVRNMLSPADFGPKLLKVIKEHFPQDVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIB component, Ascorbate-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POC1B_MOUSE
Sequence: MASGLEDPILERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVSFSKDGELLTSGGADAQVLIWRTNFIHLHCKDPKRNLKRLHFEASPHLLDIYPRSPHSHEDRKETIEINPKREVMDLQSSSPPVVDVLSFDSTTMTDSTYRAVPGKGEDICRYFLNPLLMPECSSTTVKKRPEDVSDVPSESLRSVPLAVADALEHIMEQLNILTQTVSILEQRLSLTEDKLRDCLENQQKLFSAVQQKS
What is the function of this protein?
Plays an important role in centriole assembly and/or stability and ciliogenesis.  Involved in early steps of centriole duplication, as well as in the later steps of centriole length control.  Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation.  Required for primary cilia formation, ciliary length and also cell proliferation.  Required for retinal integrity.
What are the official names of this protein?
POC1 centriolar protein homolog B, WD repeat-containing protein 51B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat POC1 family.
Protein: DER_SYNE7
Sequence: MPLPIVAILGRPNVGKSTLVNRLAGSREAIVHDEPGVTRDRTYQEAFWCDRDFTVVDTGGLVFDDDTEFLPLIREQAELALAEAALAVLVVDGQAGLTAADNEIADWLRHQNRPIVVAVNKCESPDKGAAQAAEFWSLGFGEPLPISSIHGSGTGELLDRVLELLPPADEAAGDETEIGVAIVGRPNVGKSSLLNSFLGEQRAIVSPIAGTTRDAIDTVIERNDQRYRLVDTAGIRRKRGVDYGPEFFGINRSFKAIRRADVCLLVIDVLDGVTDQDQKLAGRIEEDGRACVIVVNKWDAHEKDSSTIYEVERQLRDRLYFLDWAPMIFVSALTGQRVEKILDQVNTVVEQHRRRVGTSVINEVLGDAIAWRTPPTTRQGRQGRIYYGTQVTTQPPSFTLFVNDPKLFGESYRRYIERQFRESLGFSGTPIRLFWRGKKSRELERGANRATRV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: DTD_ACISJ
Sequence: MIGLLQRVREARVEVAGEIVGRIGPGLLALVCAEQGDSEAQADKLLAKMLKLRIFSDEAGKMNRSVQDLDGQGTCGGLLIVSQFTLAADTRGGNRPSFTQAAPPAQGERLYDYFVAQARAVHPMVATGRFAADMQVHLVNDGPVTLPLRIAPPG
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1297_STAS1
Sequence: MIKTVYVTGYKSFELNIFKDDAPEVSYLKKFIEHKLKQLIEEGLEWVLIQGQMGIELWTAEVVLALKATYPDLKLGIITPFYGHIDRWNEQNQAKYNHIAHHADFVDSVFHSSYEGPHQFKQTDQFMLAHSDTTLLIYDEEQEASPKFFKQMLVDFMEKTNYTCDIVTFDELTEFINDLQWSQEQSFE
What are the official names of this protein?
UPF0398 protein SSP1297.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: CAIB_ECOLC
Sequence: MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLATHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAZE_STAEQ
Sequence: MLSFNQNRNHSLEQSLKEGYAQMADLNLSLATEAFPIECEACDCNESHLISNSKNE
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity.
What are the official names of this protein?
Antitoxin MazE.
What is the protein family that this protein belongs to?
Belongs to the MazE/EndoAI family.
Protein: CYB_DIPCA
Sequence: SALFLAMHYTPDTLTAFSSVAHICRDVNYGWLIRYMHANGSSLFFICLYLHIGRGIYYGSYSYTETWNIGIILLFLTMA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IGF2_ONCMY
Sequence: METQKRHEYHSVCHTCRRTENTRMKVKMMSSSNRVLVIALALTLYIVEVASAETLCGGELVDALQFVCEDRGFYFSRPTSRSNSRRSQNRGIVEECCFRSCDLNLLEQYCAKPAKSERDVSATSLQIIPMVPTIKQDVPRKHVTVKYSKYEAWQRKAAQRLRRGVPAILRARKFRRQAVKIKAQEQAMFHRPLITLPSKLPPVLPPTDNYVSHN
What is the function of this protein?
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.  Acts as a ligand for integrin which is required for IGF2 signaling.
What are the official names of this protein?
Insulin-like growth factor II, IGF-II, Erythrotropin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_CHLAA
Sequence: MTELHHLTVTAAQAALAAGDITAVELTEACLARINATEPTIRAFLHLTPDAALAAARAADERRQQGRSLGPLDGIPIAIKDVICTDGVPTTAGSRILAGFRPPYNATVIERLVAAGAVLVGKLNCDEFAMGSSTENSAYQITTNPWDPTRVPGGSSGGSAAAVAAGQVPATLGTDTGGSIRQPAALCGISGLKPTYGRVSRYGLIAYGSSLDQIGPMAWTVADLAVLLNVIAGHDPRDGTSAPIDTPDYTTALTGDIRGLRIGIPREYFVEGMEPGVESATRTAIEVLRDLGAILVDVSLPHTRYALPTYYIIAPAEASANLARFDGVRYGFRAEGETMWEQIEQTRGQGFGPEVRRRIMLGTYALSAGYYDAYYRRAQQVRTLIKRDFEQVFTQVDLLAAPTSPTVAFPIGQKINDPLAMYLSDVCTLPINLAGVPALVVPCGFSEGLPVGLQLIGRPFDEATLLRVGDAYQRLTEWHTQRPRLVV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ENGB_FRATF
Sequence: MNYSKAKYIMGAAKVSQLPEDTGVEVAFAGRSNAGKSSALNTLTDQKGLARVSKTPGRTQLINLFDLGNNNRLVDLPGYGYAKVSESIKRQWQSEMENYLTSRKCLNGIVLLVDSRHELKEFDSLMIEMAISFDLNLHILLTKADKLNNKERAQANRMIESFLKTFVSTDKISYQLFSSLTKMGLDKFKEKLDTWYQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RL27_YERPG
Sequence: MAHKKAGGSTRNGRDSESKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGINVGCGKDHTLFALADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: IF2_MYCLE
Sequence: MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_OENOB
Sequence: MAERKIRIRLKAYEYRTIDASAAKIVETAKRTGAQVVGPIPLPTERTIYTILRSPHKHKDSREQFEMRTHKRLIDLVNPTDKTVDSLRKLDLPAGVAIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RS21_SULSY
Sequence: MATVIVEGDFEKALKKFKKIIEKEGILTEYKRREFYEKPSVKRKRKERAARKRLIKALKKKGLL
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: TRUD_CHRSD
Sequence: MSETPIWPPRWPRAHGGPLAAGDFRATPEDFVVEEVFDFAPEGQGEHLWLWIEKRDLTTPEAAKRVARACGVRPRDVGYSGLKDRVAVTRQWLSVHLPGREAPAELTATLATSGIAILDARRHPRKLKRGVHRLNRFTLRLTGDIAEHPGLSRQWQTLCEAGVPNYFGPQRFGREGRNLIMARSAFARGWRKRDDPHGMQLSAARSFLFNEVLAARLRTDCWRTPRDGDVLALAGSASRFVTETVDATLLDRARRGDVAPTGPLWGKGRQESGAEVAALEADIMATHAALSQGLEAAGARMDRRPLCLRLETPALRLDEEGGVVVSFGLPRGAFATAVLRELMQHPVL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: CRCB2_LACAC
Sequence: MNFLLAGIGASIGAMLRYAITNYGKKHWEWIGNKFSNLPTPTLFINLTGAFILGFIFGIKTNVFIYAIVGTGVLGGYTTFSTMNTELVELYKSKNYRGFIFYALSSYLGGLILVFVGYYLAILF
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IGA3_HAEIF
Sequence: MLNKKFKLNFIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVEVRDKNNRPLGNVLPNGIPMIDFSVVDVDKRIATLVNPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVSSEENRYYTVEKNEYPTKLNGKAVTTEDQAQKRREDYYMPRLDKFVTEVAPIEASTDSSTAGTYNNKDKYPYFVRLGSGTQFIYENGTRYELWLGKEGQKSDAGGYNLKLVGNAYTYGIAGTPYEVNHENDGLIGFGNSNNEYINPKEILSKKPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDYWAGYNKKSWQEWNIYKPEFAEKIYEQYSAGSLIGSKTDYSWSSNGKTSTITGGEKSLNVDLADGKDKPNHGKSVTFEGSGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGKTVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQHAFASVGIVSGRSTLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDEGARLVNHSTSKHSTVTITGDNLITDPNNVSIYYVKPLEDDNPYAIRQIKYGYQLYFNEENRTYYALKKDASIRSEFPQNRGESNNSWLYMGTEKADAQKNAMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNGDLNVQQGTLFLSGRPTPHARDIAGISSTKKDSHFSENNEVVVEDDWINRNFKATNINVTNNATLYSGRNVESITSNITASNNAKVHIGYKAGDTVCVRSDYTGYVTCTTDKLSDKALNSFNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADNSNNVTKYNTLTVNSLSGNGSFYYLTDLSNKQGDKVVVTKSATGNFTLQVADKTGEPNHNELTLFDASKAQRDHLNVSLVGNTVDLGAWKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSMNKNYSSSQYRRFSSKSTQTQLGWDQTISNNVQLGGVFTYVRNSNNFDKATSKNTLAQVNFYSKYYADNHWYLGIDLGYGKFQSKLQTNHNAKFARHTAQFGLTAGKAFNLGNFGITPIVGVRYSYLSNADFALDQARIKVNPISVKTAFAQVDLSYTYHLGEFSVTPILSARYDANQGSGKINVNGYDFAYNVENQQQYNAGLKLKYHNVKLSLIGGLTKAKQAEKQKTAELKLSFSF
What is the function of this protein?
Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.
What are the official names of this protein?
Immunoglobulin A1 protease autotransporter.
What are the subcellular locations of this protein?
[Immunoglobulin A1 protease autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Immunoglobulin A1 protease]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Immunoglobulin A1 protease translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: DNAA_HELPG
Sequence: MDTNNNIEKEILALVKQKVSPIEYENYFSQLKYNPNASKSDIAFFYAPNMLLCNWITAKHGALLKEILSQNKVGMHLAHSVDVRIEVAPKIQINAQANINYKAIKTSVKDSYTFENFVVGSCNNTVYEIAKKVAQSDTPPYNPVLFYGGTGLGKTHILNAIGNHALEKHKKVVLVTSEDFLTDFLKHLDNKTMDSFKKKYRHCDFFLLDDAQFLQGKPKLEEEFFHTFNELHANSKQIVLISDRSPKNIAGLEDRLKSRFEWGITAKVMPPDLETKLSIVKQKCQLNKITLPEEVMEYIAQHISDNIRQMEGAIIKISVNANLMNAPIDLNLAKTVLEDLQKDHAEGSSLENILLAVAQSLNLKSSEIKVSSRQKNVALARKLVVYFARLYTPNPTLSLAQFLDLKDHSSISKMYSSVKKMLEEEKNPFVLSLREEIKNRLNELNDKKTAFNSSE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF4_HUMAN
Sequence: MSTRKRRGGAINSRQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVDLTHNDSVVIVDERRRPRRNARRLPQDHADSCVVSSDDEELSRDRDVYVTTHTPRNARDEGATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI
What is the function of this protein?
E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-, 'Lys-11'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination of those substrates and their subsequent targeting to the proteasome for degradation (PubMed:18408734, PubMed:19307308, PubMed:35013556).  Regulates the degradation of several proteins including PML and the transcriptional activator PEA3 (PubMed:18408734, PubMed:19307308, PubMed:20943951).  Involved in chromosome alignment and spindle assembly, it regulates the kinetochore CENPH-CENPI-CENPK complex by targeting polysumoylated CENPI to proteasomal degradation (PubMed:20212317).  Regulates the cellular responses to hypoxia and heat shock through degradation of respectively EPAS1 and PARP1 (PubMed:19779455, PubMed:20026589).  Alternatively, it may also bind DNA/nucleosomes and have a more direct role in the regulation of transcription for instance enhancing basal transcription and steroid receptor-mediated transcriptional activation (PubMed:12885770).  Catalyzes ubiquitination of sumoylated PARP1 in response to PARP1 trapping to chromatin, leading to PARP1 removal from chromatin by VCP/p97 (PubMed:35013556).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF4, RING finger protein 4, Small nuclear ring finger protein, Protein SNURF.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Nucleus, nucleoplasm.