PharMolix/UniProtQA huggingface dataset:
Protein: EFG_BRUME
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTMTERILFYTGKNHKIGETHDGASTMDWMEQEQERGITITSAATTTFWQGRDGKKRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYHVPRMVFVNKMDKIGADFYRSVEMVGSRLGAVALPVQLPIGAENDFVGVVDLIEMKALTWDGTIGAPATVGEIPADMADKAEEYREKLIELAVEIDEAAMEAYLEGTMPTNDELRALIRKGTIEVKFHPILCGTAFKNRGVQPLLDAVVEFLPAPTDVPAIKGIDVKTETETTRESSDEAPLSMLAFKIMNDPFVGSLTFTRIYSGKLTKGVSLENTVKGKRERIGRMLQMHSNSREDIDEAFAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPDPVIEIAIEPKTKADQEKMGIALNRLAAEDPSFRVKSDEESGQTIIAGMGELHLDILVDRMKREFKVEANVGAPQVAYRESITRAAEIDYTHKKQSGGSGQFARVKIIFEPHDGDDFIFESKIVGGSVPKEYIPGVQKGIESVMGAGPLAGFPMLGVKATLIDGAYHDVDSSVLAFEIASRAAFREGAQKAGAQLLEPIMKVEVVTPEDYVGDVIGDLNSRRGQISGTEARGIATVVNAMVPLANMFGYVNSLRSMSQGRAQYTMQFDHYEPVPTAVAQEIQKKFA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOVP_MRFVC
Sequence: MPLTPTPSIRPSRPTSFSMSGPTTLGVRQTSCSSSLRSSPSSSPDSPTSPTSSTTGSCPKTPPGTPPLPRTSRTARPSSCMMLSCITPQGRSLTSSSSVPSSRRSMPPLSFRLSRASRISRSIRKFTASVFRVLTLSTSRRATQPPTTRSRVRPSTGSRPPVSPLVTSSSPSPFSTLSARSIPSSSSVAALPSFRPKTLLPSAFRTPSPSPLPPPSTRTFVTGWSPARCTTRSSIMSEPSAFGLPTPPASSGLRSASLSTAGSPLPPGTTFSTSRSRPPPFVPTPRIPFSSRPSLACPTGFAPTLGRSGAWLPPRPLSLPGPLPVPSAGSSPFTPTVSGCSASTSSAGGSGLVSHSMAPSQGFFGRPIQPAARQCSLPTPPLSAKSLLVWQTGVLPPPSGRVCSPRPLRRPGSPTQPWP
What is the function of this protein?
Cell-to-cell movement.
What are the official names of this protein?
Putative movement protein.
Protein: NADK_CERS1
Sequence: MTPQRIGFVASSAPVAQEALNVMAARYGQCPLPEADAIVALGGDGFMLQTLHETQSLDIPVYGMNRGTVGFLMNGYAEDGLRERLAEAEEEILNPLAMTAVTGAGEVFHRIAINEVSLLRAGPQAAWLKISVDGKVRMEELVCDGALVCTPAGSTAYNYSAHGPILPIGADVLALTAIAPFRPRRWRGALLPKTALVRFDVIDAQKRPVMADADGRSVRDVVSVEIRTEPAVRHRLLFDPGHGLEERLIREQFV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEX11_MOUSE
Sequence: MDRITDFYFLDFRESVKTLIITGNSWRLQEMIDRFFTNISNFNRESLTEIQNIQIEEIAVNLWNWAVTKRVELSVRKNQAAKLCYIACKLVYMHGISVSSEEAIQRQILMNIKTGKEWLYTGNAQIADEFFQAAMTDLERLYVRLMQSCYTEANVCVYKMIVEKGIFHVLSYQAESAVAQGDFKKASMCVLRCKDMLMRLPNMTKYLHVLCYNLGIEASKRNKYKESSFWLGQSYEIGKMDRRSVEPQMLAKTLRLLATIYLNCGGEAYYTKAFIAILIANKEHLHPAGLFLKMRILMKGNSCNEELLEAAKEILYLAMPLEFYLSIIQFLIDNKRESVGFRFLRIISDNFKSPEDRKRILLFYIDTLLQKDQDMIAEEKIKDVLKGYQTRSRLSRDLVNWLHNILWGKASRSVKVQKYADALHWYSYSLKLYEYDKADLDLIKLKRNMVSCYLSLKQLDKAKEAIAEVEQKDPTHVFTRYYIFKIAIMEGDAFRALQVVSALKKSLMDGESEDRGLIEAGVSTLTILSLSIDFALENGQQFVAERALEYLCQLSKDPKEVLGGLKCLMRIILPQAFHMPESEYKKKEMGRLWNYLNTALLKFSEYFNEAPSTLDYMVNDANWFRKIAWNLAVQSEKDLEAMKNFFMVSYKLSLFCPLDQGLLIAQKTCLLVAAAVDLDRGRKAPTICEQNMLLRTALEQIKKCKKVWNLLKKTGDFSGDDCGVLLLLYEFEVKTKTNDPSLSRFVDSVWKMPDLECRTLETMALLAMDKPAYYPTIAHKAMKKLLLMYRKQEPVDVLKYSVCMHNLIKLLVADEVWNISLYPLKEVQSHFKNTLSIIRQNEGYPEEEIVWLMIKSWNIGILMSSKNKYISAERWAAMALDFLGHLSTLKTSYEAKVNLLYANLMEILDKKTDLRSTEMTEQLRALIVPPEDQGSVSSTNVAAQNHL
What is the function of this protein?
Regulator of crossing-over during meiosis.  Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.
What are the official names of this protein?
Testis-expressed protein 11, Protein ZIP4 homolog, ZIP4H.
What is the protein family that this protein belongs to?
Belongs to the SPO22 family.
What are the subcellular locations of this protein?
Chromosome. Note=Forms arrays of discrete foci along synaptonemal complexes in spermatocytes and fetal oocytes.
Protein: TDA11_YEAS6
Sequence: MNKFDEFIESNEKDLDVDTSTRNSIISMSPVRKTGRKIRSASSNGYRLEHHRTSSAGSMHSQRLMTPTRLNDQDHPLQAKPDARRVVTRHSSVSVPNAMSKRRSLIQPMVVPTTPESQNNLPSVSHSEGSYGIPLESTTVLSSEQAMASGLRRPRNGSSQSVNSMIATTIPTNGVDVSALLQSLATKELELLECKQKIEDLKKQTQHEEQNYTRRARELHELKEQVSKHLDPSLNTPVKNRAFSPVYQNIPLESRTENAGNSSLPSSVSKPKNMGHQSTNQSRSVSPQDIQERRQRDDSSDSSKQSLWSKPLALFNQFDKIIQHEIERTLNWDDSLSGTPEVQEGTPTSNSESSAQQYDNEAPGARQKSPSQGSVSRSLWSFVSDVKAGLLGIEEENDNDVITDNRCDPVYKSDRQHEQKKSTHKITNRGQAEDSGDDSSLNMRKFKTTTKFQKDNAGNNSLTDESGHRTREKKVKEVVTS
What are the official names of this protein?
Topoisomerase I damage affected protein 11.
What is the protein family that this protein belongs to?
Belongs to the TDA11 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCL3_MOUSE
Sequence: MKVSTTALAVLLCTMTLCNQVFSAPYGADTPTACCFSYSRKIPRQFIVDYFETSSLCSQPGVIFLTKRNRQICADSKETWVQEYITDLELNA
What is the function of this protein?
Monokine with inflammatory, pyrogenic and chemokinetic properties.  Has a potent chemotactic activity for eosinophils.  Binding to a high-affinity receptor activates calcium release in neutrophils.
What are the official names of this protein?
C-C motif chemokine 3, Heparin-binding chemotaxis protein, L2G25B, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, SIS-alpha, Small-inducible cytokine A3, TY-5.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLPG_SALDC
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRGELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVLVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAGWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABH_HYPNA
Sequence: MGRRSFIRGTGSYLPERVLTNDELSEMVETTDAWIQERTGIKKRHVAADGELTSDIAVHAARRALEAAGMQASEIDLIVLATTTPDQTFPATATAVQAKLGTGPGAAFDVQAVCSGFLFALATADSLMKQGLFHKALVIGAETFTRIIDWSDRGTCVLFGDGGGAIVLECVEWDGADDAGVITHHVRTDGTKSNLLYVDGGVSSTGTIGHVRMEGNKVFKHAVTNISAAIEAVLTETGLTSADIDWFVPHQANKRILDGVAKKMSIPEEKVVITVSEHANTSAASIPLALDHVVRSGRAKPGDLILSEAMGGGFSWGASLFRL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPPA_ECOSE
Sequence: MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVEKEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: PVK3B_PANVI
Sequence: GSSGGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3b, PanVi-PVK-3b.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSIA_DICDI
Sequence: MKLLIYLFILTFYKTIVLTQTPSTHLDVDITIYDQLPLYNNNFEPETGSLTKNLVQTTLGSDGLPVLNSYSNLTYSNKNGRMYSPELFKYFFAPNQISNTTFNCGRNFPIKKQLKLLRTASGNYIYDNDFFFPIDYEGFDTDPANRIYKDDESTNKTYHNYHFCFQFDNRFLFKGNETFKFTGDDDVWVFINKQLVVDLGGTHPAASSSVDLSTLGLTVGKVYPFNFFYCERHTSRSTIRIETSLELYCDKYDYCGVCNGDGSTCCNPITDCNDDDLCTNDVCPPSDTVIDPSLPISFYCQHHPTPDPLVSDKCFESVCNSTTGSWFLNATICVEKEGLINTGCDGNTGCIYEPPTQTPTETPTQTPTETPSQTPTETPSQTPTETPSQTPTCTQHPTPTPTCTEHIKTPKPTPTPTCTKHPKPTPTCTEHTKTPKPTKTLKPTPTPKPTQTPKVPQCGKCEKLSSCKTYCEKKDCDDCQRELDGYKFDRCKTYSCDPIKGCIKTDKCKQGNDPCLKPVCNQYTGFCSQERVVSDKCKCDDKGKKGFGLGIGIGINA
What is the function of this protein?
Growth factor that can induce isolated amoebae to differentiate into prespore cells.
What are the official names of this protein?
Protein psiA, Prespore-cell-inducing factor A.
What is the protein family that this protein belongs to?
Belongs to the prespore-cell-inducing factor family.
What are the subcellular locations of this protein?
Secreted.
Protein: TERS_ECOL6
Sequence: MKVNKKRLAEIFNVDPRTIERWQSQGLPCASKGSKGIESVFDTAMAIQWYAQRETDIENEKLRKELDDLRAAAESDLQPGTIDYERYRLTKAQADAQELKNAREDGVVLETELFTFILQRVAQEISGILVRVPLTLQRKYPDISPSHLDVVKTEIAKASNVAAKAGENVGGWIDDFRRAEGS
What is the function of this protein?
Involved in the initiation of the phage DNA packaging into the prohead.  Processes replicating concatemeric DNA into pieces of unit length with cohesive ends (By similarity).
What are the official names of this protein?
P21 prophage-derived terminase small subunit, Gp1.
What is the protein family that this protein belongs to?
Belongs to the terminase small subunit family.
Protein: PROA_BIFAA
Sequence: MNADVFEAVCAMGDAARTAQSQLAQANTEAKNQLLNAIADALDQHADDIAAANTLDMNKAETDGMDAGKLDRLKFDQQRITAAAQGVRHVASLPDPIGEIVRGYHLENGLRLQQVRVPIGVLGMIYEARPNVTVDVASLCIKSGNAVLLRGGHAAEHTNAATLAVIADVLTKHGYDHNMIATVDQYGRDGATAMMEARGHIDVLIPRGGAGLIQAVVRNSKVPVIETGAGNVHIYVDRTGNPDKAIPILINAKTQRVGVCNATEKLLVHKDIAESFLPKAAAALAAAGVEMHADERAYGIIEHAGIANAQLVHATDEDWDTEYLALKIGIKVVDSLDEAIAHINRHSTGHTESIIAEDYSAIEEFTARIDSAVVMVNASTRFTDGGVFGFGAELGISTQKMHARGPMGLHEMTTTKWIGYGTGQVRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSN_ECO57
Sequence: MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRSRVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGEK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: RS2_LACJO
Sequence: MTVVTMKQLLEAGVHFGHQTRRWDPKMAPYIFTQRNGIYIIDLQKTIKMLDDAYNYVKAVAQDGGVFLFVGTKKQAQDAVKEEATRAGQYYVNQRWLGGTLTNWTTIQSRVKRLKELKQMSEDGTFDVLPKKEVALLTKEMEKLERFLGGIEDMPRIPDVMFVVDPKKEKIAVHEANILGIPVVAMVDTNTDPDPIDVVIPANDDAIRAIRLISGAMADAIIEGKQGQDDSEDVEKEMADKAAAEDDEEESIEVVVEKSED
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: LMTD1_MOUSE
Sequence: MMKEASEPLASVTSINKQDSKVQDGEIRKEKIGTITPSKQHSSVHFFPKIMDSDSTTLIPLSRSFSQEMPIGFYQITSTQNSSTLSSRGQLASKSTILSCSHKDSSLGKQSTSSMVPRRQPQSSSDVDTYTFGNGEDYFLSLFGESKKLTAHTPQAENVSEHLSVILEEVGQFTSSSLGEIKIAEVNIKGLFVRLVNSSNEKEVEIGNHILQQNVNGHAVSLYQFPDNITLQANSTVTVWAAASEAKPQPPTDFVWEEQSKFRSSPDCTTILCKPNGEAIAWYTPIHWKQAWEKLETDIEFERCSVVVPSMRNHMFGWITASVSSTNEEKEEPIQKTPSQVYPVLYREKEIPPTVLPNKSPWCRNPNTSPHPYSSLIDSHDSDISESSLDTQLKPQPTKPKPDPGTKKKKAKS
What are the official names of this protein?
Lamin tail domain-containing protein 1, Intermediate filament tail domain-containing protein 1, Lamin-A-related sequence 1 protein.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: FADB_SHIF8
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLIEGAMAILRQAINGDLDWKAKRQPKQEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: ANMK_PSESM
Sequence: MDFFYIGVMSGSSLDGIDIALLKQDDRSRLVATHYIPMPEDLHAELLGLCSSGADEFARAAIAEQKWCKLVAQGVQTLLKEQNKVVADIRAIGSHGQTIRHEPARGYSIQIGNPALLAELTEITVVSDFRRRDIAAGGQGAPLVPAFHEALFDDNKDHRAVLNIGGFSNLSLIESDRPVEGFDCGPGNVLLDAWIQSQRHESYDKDGAWAASGKVDPELLKKLLSDPFFLTKGPKSTGREVFNLGWVHHHLFQLPTLAPEDVQATLLELTALTITESLQTAQAVTKELLVCGGGAHNKALMKRLAELLPDTEVNSTEKFGVDPDWVEAMAFAWLAHCCLEGVPANRPTVTGAKGRRVLGAIYPA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: CLP1_CRYNJ
Sequence: MAEQQTTELTNIDLEAGSEWRFELEADENIALRTLSSDPVFINSQELTPSAWYPIYRHTKSALYAPTSARIQVTNLPASHYTSTSTVQPQLLNLHLAMERQRILSKRGMEQRGPRVMIMGPQSSGKTTVMKNLVNLALGTGMGWTPGAIGLDPSSPPNLIPGSLSISTPSHPIPTHHLAHPLGSPPASTAANTISGDVETASWWLGALEPTNKNAEVWRVLVEHMAEAWGMRCEKDKIANISGLFLDTPAAFTVPTLGTKKDDPKARYTLVSHAIQAFDIDTIIVIGHEKLHIDLSRLPLVQSRQLNVIRIPKSGGAVDLDDHDRETAHIFQVRTYFYGEPPLPPQISSLVGKMVSLDFELSPYSFQIPWSRLVVLRVGEENSAPSSALPLGSSKILSPLRLTRVDPSGPGHVVRLLNRVLALVDVKPEDRIVPAKESEVKEEVKEEKNEKDGEIKQDGEGEKKGEGKGEGEGEGEGKDGEEEGEAEGEDDEEEVPFREEIGTREVMGFIVITAIDTFARKYTVLSPTPGRLPTTVAIAGAIEWVDSA
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor CLP1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBA4_ASHGO
Sequence: MTGESLDGSLHALTIELDALRRENANLKQQLKEKDGACGELPMSLEEFQRYGRQMIVGETGGLSGQVKLRSARVLIVGAGGLGCPALQYLAGAGIGHLGIVDNDVVEESNLHRQPLHDTSKVGLLKCDSAKEALSRLNPYCSIKTYPVRLSYANAFEIFPSWDLILDCTDSPMSRYLISDVAVNLGKTVVSGSGLGTEGQLSIYNFENKGPCYRCFYPIPPRPGSVVSCQSGGVLGPCIGVLGIMMAVEALKILFGIYTLENFKPFLMQYSGFPYQTLRMFKMRNRKQGCLCCGDNPTITKSTIESGHIKYEAFCGAINYDVLSKDERLSASEFEANYWSQKERGFVCLDVRPRLHYEISHLPGTYNMTVKELDEMEGSIEELQKHIPVITPDLDIVVLCRYGNDSRLATRILKDKFKLRNVRDVKGGYFAYIDEINPSLPKY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1.  Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase UBA4, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_BACCZ
Sequence: MRTTFMAKANEVERKWYVVDAEGQTLGRLASEVASILRGKNKPTFTPHVDTGDHVIIINAEKIHLTGNKLNDKMYYRHTNHPGGLKQRTALVLRTNYPVQMLELAIKGMLPKGRLGRQVSKKLNVYAGAEHPHQAQKPEVYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: FABV_XANOP
Sequence: MIIHPKVRGFICTTTHPLGCERNVLEQIAATRARGVRNDGPKKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKAAGLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVVYSLASPVRKLPGSGEVKRSALKPIGQTYTATAIDTNKDTIIQASIEPASAQEIEDTITVMGGQDWELWIDALEGAGVLADGARSVAFSYIGTEITWPIYWHGALGKAKVDLDRTAQRLNARLAKHGGGANVAVLKSVVTQASAAIPVMPLYISMVYKIMKEKGLHEGTIEQLDRLFRERLYRQDGQPAEVDEVDEQNRLRLDDWELRDDVQDACKALWPQVTTENLFELTDYAGYKHEFLKLFGFGRTDVDYDADVATDVAFDCIELV
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: MDH_POLSJ
Sequence: MSKKPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEVPVEGPQKALKGVMMELDDCAFPLLAGMEAHSDPMTAFKDADYALLVGSRPRGPGMERAELLAVNGAIFTAQGKALNAVASRNVKVLVVGNPANTNAYIAMKSAPDLPRKNFTAMLRLDHNRAASQIAAKTGKAVADIEKLTVWGNHSPTMYADYRFATINGESVAKMINDQEWNANVFLPTVGKRGAAIIEARGLSSAASAANAAIDHMRDWALGTNGKWVTMGIPSDGQYGIPKDTMFGFPVTCENGEYKLVEGLEIDAFSQERINKTLEELQGEQAGVAHLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: KDPA_ANADE
Sequence: MTAAALAEIAAFFGLLTAAAVPLGAYAARVLSTAPPHGRGPVARLERGLYRLAGVDPAEQMGWRRYAAAALTFNAAGLLAVFALERLQAALPGNPAGLPAVSPLVAWNTAVSFATNTNWQAYGGESTMSHLTQMGALTVQNFLSAATGISVLAALVRALAGPAGSGLGSFWVDLTRVTLRLLLPLAAALALLLAWQGVPQTSSAAARWPTLSATAASPGAEQVVALGPVASQVAVKQLGTNGGGYFNANSAHPYENPTPLSNLLEALSILLVPAALCFAFGALVKDRRQGWTVYSAMLAILVPLTVATVSAEQRGNPALAALGVDASPSALQPGGNMEGKEARLGPVDSAIWAAATTAASNGSVNAAHDSFTALGGLWPLWLMQLGEVVFGGVGSGLYGMLLFAILAVFLAGLMVGRTPEYLGKKVEAYEVKMASLAILAPSATVLLGTAAACLLPAGYGAVGNPGPHGFTELLYALSSTANNNGSAFGGLAASTPFWTLLTGVAMLVGRYWVMLPVLAIAGAFARKRPVPAGPGTLPTHGPLFAGLLVATVLLVGALTFLPALALGPVIEHLQAVPR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLMU_METCA
Sequence: MEVIALILAAGQGTRMRSGLPKVLHRIGGLCLLEHVYRLAAALEVRETVIVYGHGGEQALSALGHLPATWIEQKKRRGTGHAVMQAVDRIGDDSTVLVLYGDVPLLRRETVETLLHHAGESSLGLLTVELDNPTGYGRIIRDASGRVLRIVEEKDATPEERAVREVNTGILAVEGAPLKRWLKALRNDNAQGEYYLTDIVAMAVAEGYFIDATHPTSPDEVLGVNDRRQLAELERIYQVHQARALMERGVTLRDPARFDLRGEIVELGRDVEIDVNVILEGRIALGDEVRIGPNVYLKDTVIGPGVAVLANSVIEGAVIGAGSRVGPFARLRPESVLAEGVHIGNFVEVKQSDIAVGSKVNHLSYIGDASIGRGVNVGAGTITCNYDGVAKHRTIIEDGAFIGSDTQLVAPVRVGRNATIGAGSTITRDTPEDCLTLSRARQLSVEGWKRPEKARKESCAE
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.