PharMolix/UniProtQA huggingface dataset:
Protein: SKAT1_CAEEL
Sequence: MSEEEGRERAVTVEGDAESMNDGRALVQPPARSGDVITPTRAVLTLSKSMFNAGCFSLPYAWKLGGLWVSFVMSFVIAGLNWYGNHILVRASQHLAKKSDRSALDYGHFAKKVCDYSDIRFLRNNSKAVMYFVNVTILFYQLGMCSVAILFISDNLVNLVGDHLGGTRHQQMILMATVSLFFILLTNMFTEMRIVSFFALVSSVFFVIGAAVIMQYTVQQPNQWDKLPAATNFTGTITMIGMSMYAFEGQTMILPIENKLDNPAAFLAPFGVLSTTMIICTAFMTALGFFGYTGFGDSIAPTITTNVPKEGLYSTVNVFLMLQSLLGNSIAMYVVYDMFFNGFRRKFGARFPNVPKWLSDKGFRVFWVLVTYLMAVLIPKLEIMIPLVGVTSGALCALIFPPFFEMITFWTDWKGLLTYRQRMTKIFINLVVMAIGVFAIIAGVYTNIHAIIQSFSQPDP
What is the function of this protein?
Plays a role in the accumulation of vital dyes and endogenous fluorescent compounds in lysosome related organelles.  Has an effect on lysosome related organelle (LRO) function, in a pathway with serotonin.
What are the official names of this protein?
Probable amino acid transporter skat-1, Protein suppressor of kat-1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasmic granule.
Protein: PG003_VAR67
Sequence: MDEIVNIVRDSMWFIPNVFMDNGENDGHVSVNNVCHMYFAFFDVDTSSHLFKLVIKHCDLNKQLKCGMSPLHCYVMNTRFKPSVLKILLHNGVNNFDNKDNKGHIPLHHYLIYSLSIDNKVFDILTDPIDDFSKSSDLLLCYLRYKFNGRLNYYVLYKLLTKGSDPNCVDEDGLTSLHYYCKHISAFHESNYYKSKSYTKMRAEKRFIYTIINHGANINAVTKIGNTPLHTYLQQYTKHSPRVVYALLSRGADTRIRNNFDCTPIMEYIKNDCVTGHILIMLLNWHEQKYGKLQKEEGHHLLYLFIKHNQGYGSHAFNILRYLLDRFDIQKDEYYNTMTPLHTAFQNCNNNVASYLVYIGYDINLPTKDDKTVFDLVFENRNILFNAGVIHNIIHHRLKVSLPMIKSLFYKMLEFSPYDDYYVKKIIAYCILRDESFTELHSKFCLNEDYKSVFMKNISFDKIDSIIKKCNWDISRLKDIQISDTNLYTVLRTEDIRYRTYLKAIHLDSHISFPMYDDLIEQCHLSMERKSKLVDKVLNKLKSTIDGQSRLSYLPPEIIRNIITKLSDYHLNSMLYGKNHYKYYT
What is the function of this protein?
May be involved in virus-host protein interaction through the ankyrin repeats and PRANC regions.
What are the official names of this protein?
Ankyrin repeat protein OPG003.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG003 family.
Protein: PETL_ADICA
Sequence: MFTLLSYFAFLMLALTFTLALFVGLNKIQIL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUOB_WOLPM
Sequence: MTNQILSNDDWGRYKKEGFLVTKFGDLTDYVMNWARSGSLWPMTFGLACCAVEMMHTASSRYDLDRYGIMFRASPRQSDVMIVAGTLTNKMAAALRKVYDQMADPKYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALLYGMLCLQNKIKRTRNG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DRTS_MAIZE
Sequence: MAAVLANGDSQGRPQRNYQVVVAGTRDMGIGKDGVLPWKLPGDLKFFKELTLTTSDPVKKNAVIMGRKTWESIPVKSRPLPGRLNVILTRSGSFDFATVENVVICGSMESALELLASTPYCLSIEKVFVIGGGQVLREYLKGPACEAIHLTDIQSSIECDTFIPPVDFSVFQPWYSSFPVIESNIRHSFVSFVRVRKSVAETHESNGKESTEVDTKNDKFETENFSFLPKMVYDRHEEYQYLNLVEDIIRSGAQKNDRTGTGTLSKFGCQMRFNLRKNFPLLTTKRVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASREYLNSVGLAHREEGDLGPIYGFQWRHFGAEYTDMHADYTGKGFDQLMDVIDKIKNDPEDRRIILSAWNPSDLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTYMIAQVCDLSPGDFVHVIGDAHVYRNHVRALEEQIQKMPKPFPILKINPSKKDIDSFMASDFKLVGYDPHQKIEMKMAV
What is the function of this protein?
Bifunctional enzyme.  Involved in de novo dTMP biosynthesis.  Key enzyme in folate metabolism.  Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction.  Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).
What are the official names of this protein?
Bifunctional dihydrofolate reductase-thymidylate synthase, DHFR-TS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidylate synthase family.
Protein: RS15_SHEB2
Sequence: MSLSTEVKAKILADFGRCENDTGSTEVQVALLTAQINHLQAHFKEHIHDHHSRRGLLRMVSSRRKLTAYLKRTDVARYTALIQKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y4ID_SINFN
Sequence: MAHSSDLALFRHRIAEALPSANVPTLLLLLYQFTGKEYWLTPPFLPVKSVWGDNDSGGLAAELQTEIRNAALDAIICWHSGAPVTKQDLSEEELIRMLTVSEAEPIPPEYADMMLHKLRRYAGAIPDPVSLPKGFRVLIIGAGMSGVAAAIRLRQLGISYIQVEKQDSTGGVWHAHHYPGCGVDTPGHLYSYTFASGNWSTFFPLQKEIDDYFNRVARDFGIESSIRYGTECLVTRYDEESLTWHSRLRLPNGTEETLVTNVVLSAVGGFTTPKWPNLSGLRNFDGPVVHTSKWDPEVALDGKRVAVIGNGASAMQVVPAIADRVGALTIFQRSRQWVAPFPKFQKPVPEPMQFLFREVPHYEWLYRLRLSWIYDSEVHEALQKDPAWPHPDRSVNAVNDRDREAYTQYIEGQLAGRPDLIAKVIPSYPPFGKRMLLDNGWYRTLLKPHVTLVDGAAARVEGRSIHAIDDETHEADLIIVASGYDTTRYLLPVEVIGRNGRTVRDVWDDDDCQAYLGTVVAGFPNFFMLYGPNTALGHRGSFIFTIESQIDYVLSVLRQMGEKRLVEVECRQDIYQHYNRKIQQMHQQMIWSHEGMSTFFRNDRGRIVTNSPWRLVDYWNLLKEADLDDYRTMPQVDSRLETSGVPREGVQRPGSRLRRRPS
What are the official names of this protein?
Uncharacterized monooxygenase y4iD.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: RL18_MYCBP
Sequence: MAQSVSATRRISRLRRHTRLRKKLSGTAERPRLVVHRSARHIHVQLVNDLNGTTVAAASSIEADVRGVPGDKKARSVRVGQLIAERAKAAGIDTVVFDRGGYTYGGRIAALADAARENGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: UBIE_ACICJ
Sequence: MADTSSETVDFGFSTVPRGEKRHKVREVFDSVAGRYDIMNDLMSLGVHRLWKREFVAMMDPRPHRTLLDLAGGTGDISLRWLAAGGGPVLMTDINEAMLRVGRGRAEEQARIEGIGFAVADAEALPLRDSCVDRVSIAFGLRNCTDKDRVLAEARRVLKPGGRFFCLEFSRLQVAAAQPLYEKWSFVALPAIGARVAQDRESYQYLAESIRMFPDQETLAGMMRRAGFERVSYRNLSGGIAAIHSGWRL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PP223_ARATH
Sequence: MIVVTSFVRNSAVAAVASTPWNVRLRELAYQSLFSESISLYRSMLRSGSSPDAFSFPFILKSCASLSLPVSGQQLHCHVTKGGCETEPFVLTALISMYCKCGLVADARKVFEENPQSSQLSVCYNALISGYTANSKVTDAAYMFRRMKETGVSVDSVTMLGLVPLCTVPEYLWLGRSLHGQCVKGGLDSEVAVLNSFITMYMKCGSVEAGRRLFDEMPVKGLITWNAVISGYSQNGLAYDVLELYEQMKSSGVCPDPFTLVSVLSSCAHLGAKKIGHEVGKLVESNGFVPNVFVSNASISMYARCGNLAKARAVFDIMPVKSLVSWTAMIGCYGMHGMGEIGLMLFDDMIKRGIRPDGAVFVMVLSACSHSGLTDKGLELFRAMKREYKLEPGPEHYSCLVDLLGRAGRLDEAMEFIESMPVEPDGAVWGALLGACKIHKNVDMAELAFAKVIEFEPNNIGYYVLMSNIYSDSKNQEGIWRIRVMMRERAFRKKPGYSYVEHKGRVHLFLAGDRSHEQTEEVHRMLDELETSVMELAGNMDCDRGEEVSSTTREHSERLAIAFGILNSIPGTEILVIKNLRVCEDCHVFLKQVSKIVDRQFVVRDASRFHYFKDGVCSCKDYW
What is the function of this protein?
Involved in C-to-U editing of mitochondrial RNA.  Required specifically for editing the mitochondrial NAD2 transcript.
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At3g11460, mitochondrial, Mitochondrial RNA editing factor 10.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOB_PSEE4
Sequence: MAYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGASKDQFRDVGLHAAFKSVFPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVFVRIDRRRKLPASVLLRALGYSTEEVLNTFYTTNVFHLSGEKLSLELVPQRLRGEVAVMDIHDGSGKVIVEQGRRITARHINQLEKAGVKELDVPLEYVLGRTTAKAIVHPATGEILAECNTELTTDLLVKIAKAQVVRIETLYTNDIDCGPFISDTLKIDTTSNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSAERYDLSAVGRMKFNRRIGRTEIEGSGVLSKEDIVEVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAVKERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMGQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVKEGVVSDDIVFLSAIEEADHVIAQASAAMNEKKQLIDELVAVRHLNEFTVKAPEDVTLMDVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVCVVARRGGVIDSVDASRIVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDVVARGDIMADGPSTDMGELALGQNMRIAFMAWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGAEVGAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDSRALAIEKMQLDEIRKDLNEEFRIVEGATFERLRAALNGQVVDGGAGLKKGTVITDDVLNGLEHGQWFKLRMAEDALNEQLEKAQQYIVDRRRLLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDVVLNPLGVPSRMNVGQILETHLGLAAKGLGEKIDRMIEEQRKAAELRTFLTEIYNEIGGRQENLEEFTDEEIMALANNLKKGVPMATPVFDGAKEREIKAMLKLADLPESGQMQLFDGRTGNKFERSVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GCSPA_COXB2
Sequence: MPFIPHTPDDIEKMLAVIGAESIDQLFDEIPSALANIQQVPPGLNEAGITRLMEKREPNKQLCFIGAGAYEHHIPAAVWEIATRGEFYTAYTPYQAEASQGSLQLIYEYQTMMAELMAMDVSNASLYDGASALAEAALMAVRIKRGKAQRILVPASVNPFYRKVLSSIVEQQKINVEIIPFDPTMGIVNSELLKAKNAEGAAAIIIPQPNFFGCLEAVDVLTDWAHANDLLVIASVNPTAMALLKPPGQWGQKGADIVCGEGQPLGVPLASGGPYFGFMCCKKDYVRQLPGRIVGRTVDKKGREGFTLTLQAREQHIRRSKATSNICTNQGLAVVAATIYLSLLGATGLREVALASHTQSRDLFQRLSAVKGVSPVFSSPIFHEFVVRLEKPVEEVLAAMAEQGIQAGFSLKNDYPKLGNGLLICVTDTKTDDDLMAYENALRSIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: KNT1_RAT
Sequence: MKLITILLLCSRLLPSLAQEEGAQELNCNDETVFQAVDTALKKYNAELESGNQFVLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPSLREDCVPLPYGDHGECTGHTHVDIHNTIAGFSQSCDLYPGDDLFELLPKNCRGCPREIPVDSPELKEALGHSIAQLNAQHNHIFYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSKTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVRVQETKEGTTRLLNSCEYKGRLSKARAGPAPDHQAEASTVTP
What is the function of this protein?
Kininogens are plasma glycoproteins with a number of functions: (1) as precursor of the active peptide bradykinin they effect smooth muscle contraction, induction of hypotension and increase of vascular permeability.  (2) They play a role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII.  (3) They are inhibitor of thiol proteases.
What are the official names of this protein?
T-kininogen 1, Alpha-1-MAP, Major acute phase protein, T-kininogen I, Thiostatin.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: SAPD_ECOL6
Sequence: MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELTEGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE
What is the function of this protein?
Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
What are the official names of this protein?
Peptide transport system ATP-binding protein SapD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEU1_VIBA3
Sequence: MNDQVIIFDTTLRDGEQALAASLTVKEKLQIAYALERLGVDVIEAGFPISSPGDFESVQTIAKHIKDSRICALSRAVAKDIDAAAEALKVADQFRIHTFISTSTVHVQDKLRRSYDDVVEMAVKAVKHARNYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGAKTINIPDTVGYTVPNEFGGIIKTLFDRVPNIDQAIISVHCHDDLGMSVANSIAAVQAGARQIEGTINGIGERAGNCSLEEIAMIIKTRQELLGVHTGLDHKEIHRTSKLVSQLCHMPIQDNKAIVGANAFSHSSGIHQDGMLKNKNTYEIMTPESIGLKNKALNLTSRSGRAAVKSHMDAMGYKDNEYNLDSLYEDFLKLADRKGQVFDYDLEALMHFANLRDEDDFYKLNYLSVQSGSVMSTTSIKLQCGDEEKCEAAVGNGPVDALYQCIYRLTGYEIALDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGVSTDIVEASGQALLHVINSIQRADTIAEMKQQKFATV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: Y1865_STAA1
Sequence: MAMTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
What are the official names of this protein?
UPF0435 protein SAHV_1865.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: RNPA_SYMTH
Sequence: MKKAYRLKSRLAFQSVYAQGRSVANRAAVVHVLKQQAGTPTRVGFAAGRKLGKAVVRNRAKRRLREAVRLLWPRVRQGYYIVVIARQAALDMPFPELRQKVEELFERAGLLQREG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: HCP_KOSOT
Sequence: MSMFCYQCSETLNGKACTVAGVCGKDPETSNLLDLLVWVLKGISFWATEARKLGVDDPEVNLFVAEGLFTTITNVNFDPESIGKKIEKAFALRERIMKATKEAYKEQYGKEFSKEVPEAATWYVPGDLSVWELKGAEVGALSTKDEDIRSLRELLTYGLKGIAAYTDHAYILQKFNDEILHFLQEGLAATLDDSLTVNDYVALVMKAGEFAVKAMQLLDEANTSRYGNPEITEVYTGTLPGPAILVSGHDLLDLEEILKQTEGKGINVYTHGEMLPAHAYPELKKYKHLVGNYGTSWYNQQKEFAQFNGAIVMTTNCIQKPLESYKDRIFTTGLVGWPGVKHIPNRTDGGQKDFTPVIEKALELGGLEEKPGKKIVIGFAHEQTAQVADKIIEAVKAGKIKRFVVMAGCDGRAKEREYYTEMAKRLPKETVILTAGCAKYRYNMLDLGDIDGIPRVIDAGQCNDSYSLVVTALRLKEAFGLDDINDLPISYDIAWYEQKAVAVLLALLYLGVKGIRLGPVLPAFLSPNVLKVLVENFDIKPISTVEQDLELILQGK
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMO3_HUMAN
Sequence: MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
What are the official names of this protein?
LIM domain only protein 3, LMO-3, Neuronal-specific transcription factor DAT1, Rhombotin-3.
Protein: Y59_SIRV1
Sequence: MMKIITFKIPEETLLLLDAYAIKHNMNRSEVIRLAIEKLVVDEMKNEPVPRARVEKIKF
What are the official names of this protein?
Uncharacterized protein 59.
Protein: TPIS_LACDA
Sequence: MSRTPIIAGNWKLNMNPKETVEFVNAVKDQLPDPSKVESVICAPAVDLDALLKAAEGSNLHVGAENCYWENSGAFTGETSPAVLKEMGVQYVIIGHSERRDYFHETDEDINKKAKAIFANGLTPILCCGESLETREAGKENEWVVSQIKAGLEGLTSEQVSKLVIAYEPIWAIGTGKTASSDQAEEMCKTIRETVKDLYNEETAENVRIQYGGSVKPANVKELMAKPNIDGGLVGGASLVPDSYLALVNYQD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_PHYPA
Sequence: MKFYWSQIYSWLLRTPYRSLERAYRASKKIQHIKKNYIFYNKNIISSSRRSWQAIMLYINTNLNNCVFIIYWSLLEYRISLFFFDFIKTFVLIISNFFNSFFSNLISNNVIKQDLKEIKQMNKKLAWIEASLNDLDMWKYYYSFSFFSKEKQKTVETSLTFVDLKKNNVTTAAYESIGLVPRSITRTLSGFKTELTGQSTSLVLQDFQIARYQALASLQYMLFLLFIPWGFSSLLKIWFLEPWLKNWWNTYQYQIFLNSFQEELALKRLQQIEELVWLDKIMVNSLKEPQSQDLNIEIHQKTIQLVKIYNENSLNTLLHLLTDIVYVITLSAVFILGKQRLAILNSWIQELFYSLSDTMKAFSILLLTDLCIGFHSPHGWEIVIGSFLEHLGFAHNKHIISCFVSTFPVILDTVFKYWIFRHLNRISPSIVATYHTMNE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: KRA41_HUMAN
Sequence: MVNSCCGSVCSDQGCDQGLCQETCCRPSCCQTTCCCPSCVVSSCCRPSCSQTTCCQTTCCRPSCCHPVCCQTTCRPSCGVSSCCRPLCCQTTCHPSCGMSSCCRPLCCQTTCRPSCGVSSCCRPLCCQTTCCRATCCRPSCCGSSC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 4-1, Keratin-associated protein 4-10, Keratin-associated protein 4.1, Keratin-associated protein 4.10, Ultrahigh sulfur keratin-associated protein 4.10.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 4 family.
Protein: NU4LM_PATPE
Sequence: MTSTFIITITIFYLGLLGILINRLHFLSILLCLELLLISLFLSLTVWAINANTTFLLTNNLILLTLSACEASAGLSLMVALSRTHNSDLVSTINILQQ
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: POXQ_PENOX
Sequence: MARIPLEFLSITLPVLLLAYCLAIEYEVSLPTIAHTSPASNPEEYLQSIYEQLNLDLPSTCTVNHLSAFDNTPTSLLNFSTSPVEHFDAPKLPSGLNATAGEQWAFDGTSSSGRSGLLLGIYRDASYAFLGPGNFRLSLDLVWDNSTTWSTVDYLSSSTVHTCTDKVVGIWSHSADHYYVFTVTADAKHARIHFHTPDVVGAVDLYSTTPARYPDGALFPSEVSVTQNAPMLHWVEPIPGGLIDVDLKVKDTPFRWTGLGGHERWWSAKGWLDLMTHWEAVRLMAGPYVLSFWQPTSRVNGVAYPSAFLTKYGEKVFSAVSGKVSEVEDYILYRPVRMEKQARETGYEVDLVSPAQGRRWVFGLEYRNQEFEFELGDAAGGRAYVGRAKGGEVHADDKPEEPSEGVFFIEHVDVKALTVPRAYVVVSFEFGPPIHGADIWVAC
What is the function of this protein?
Diels-Alderase; part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety (PubMed:28365998).  The first step of the pathway is provided by the HR-PKS poxF that serves in a new mode of collaborative biosynthesis with the PKS-NRPS poxE, by providing the olefin containing amino acid substrate via the synthesis of an ACP-bound dec-4-enoate (PubMed:28365998).  The cytochrome P450 monooxygenase poxM-catalyzed oxidation at the alpha-position creates the enzyme-bound 2-hydroxydec-4-enoyl-ACP thioester, which may be prone to spontaneous hydrolysis to yield 2-hydroxydec-4-enoic acid due to increased electrophilicity of the carbonyl (PubMed:28365998).  2-hydroxydec-4-enoic acid can then be further oxidized by poxM to yield the alpha-ketoacid 2-oxodec-4-enoicacid, which is reductively aminated by the aminotransferase poxL to yield (S,E)-2-aminodec-4-enoic acid (PubMed:28365998).  The Hybrid PKS-NRPS synthetase poxE then performs condensation between the octaketide product of its PKS modules and the amino group of (S,E)-2-aminodec-4-enoic acid which is activated and incorporated by the adenylation domain (PubMed:28365998).  The resulting aminoacyl product can be cyclized by the Diels-Alderase PoxQ and reductively released by the reductive (R) domain of poxE to yield an aldehyde intermediate (PubMed:28365998) (Probable).  The released aldehyde is then substrate for a Knoevenagel condensation by the hydrolyase poxO followed by an oxidation at the 5-position of the pyrrolidone ring (PubMed:28365998).  The presence of the olefin from the amino acid building block allows for migration of the substituted allyl group to occur (PubMed:28365998).  This allylic transposition reaction takes place in a conjugate addition, semipinacol-like fashion to yield a succinimide intermediate (PubMed:28365998).  Iterative two-electron oxidations of the C7 methyl of the succinimide intermediate to the carboxylic acid can be catalyzed by one of two remaining cytochrome P450 monooxygenasess poxC or poxD to yield oxaleimide A (PubMed:28365998).  Subsequent oxidation yields the maleimide scaffold oxaleimide I (PubMed:28365998).  Both oxaleimide A and oxaleimide I can undergo oxidative modifications in the decalin ring to yield the series of products oxaleimides B to H (PubMed:28365998).
What are the official names of this protein?
Diels-Alderase poxQ, Oxaleimides biosynthesis cluster protein Q.
What is the protein family that this protein belongs to?
Belongs to the Diels-Alderase family.