PharMolix/UniProtQA huggingface dataset:
Protein: SYS_SHEDO
Sequence: MLDPKFLRTELDATAERLASRGFALDTAHLSQLEETRKSLQVETEELQASRNAISKSIGQAKSRGEDVSAIMAQVGDLGSKLDAKKAELAELLHAINLIAMSTPNLPDESVPCGKDETENLEVRRWGTPRSFDFPVKDHLDLGEALGGLDFKSAVKITGSRFIVMKGQLARLNRALGQFMLDLHTQEHGYTETYVPLLVNEDSLLGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNLVRDTIVEVSDLPLKFTAQTSCFRSEAGSYGRDTRGLIRQHQFEKVELVQIVKPEDSMQALEELTLHAEKVLQLLGLPYRTMLLCTGDMGFGASKTYDLEVWLPAQNTYREISSCSNMKDFQARRMQARYRNPEDNKPALLHTLNGSGLAVGRTLVAILENYQNADGSITVPDVLHKYMGGTTLIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM1_YARLI
Sequence: MNWYVRLLQKYPYRMAVTSTSSLFMIGDCVSQRYFSDKPYEPMRTARAGIYACAFAPAMTAWFRFLGQQQLPVIAKVAIDQAVFAPSSIGYYFSVMGLLEGKSPDTIWQSLKNQYWDTLKCGWMIWPAFQLFNFGIVPPNFRVLASNCCGLVWNTFLAYQNANKMEKGHVADLVIEEVKEEVKEVKQEVLAEVKVIKGFVKQ
What is the function of this protein?
May be involved in cellular response to stress.  Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).
What are the official names of this protein?
Protein SYM1.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HEMA_INBF7
Sequence: DRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVALGRPKCTGTIPSAKASILHEVKPVTSGCFPIMHDRTKXRQLPNLLRGYEHIRLSTHNVINAEKAPGGPYKIGTSGSCPNVTNGNGFFATMAWAVPKNDNNKTATNSLTVEVPYICTEGEDQITVWGFHSDNETQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQAEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: THIC_LEPIN
Sequence: MEPVQKLQIPYKSIRLSDGTEYQSYHTEGALSGKQPADYKNGIPAFRKEWIQKRFNHSNHSQMYFAKKGIITEEMRYAAFRENMEPEFVRSEIACGRAILPSNRNHPELEPMIIGKNFLVKINANIGNSTFSSSIEEEVEKLHWAIKWGADTVMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVKGKTENLNIQIFLETLEEQAEQGVDYFTIHAGVLLRYIPLTTNRITGIVSRGGSILAKWCQAHHKENFLYTHFDEILKVMKKYGVSISLGDGLRPGSIADANDKAQFSELETLGELTQLAWKEDIQVMIEGPGHVPMNLIKENVDLQTKICQEAPFYTLGPIVTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKEDVKQGVIAYKIAAHAADLAKGHPGAIDRDNLLSKARFEFRWEDQFSLSLDPETAKTFHDEMLPQDRMKTAHFCSMCGPHFCSMNLTQELRKFAQEKEIQES
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: LSPA_ECOLC
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTN5_HUMAN
Sequence: MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
What is the function of this protein?
May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 5, Neural-specific protein-tyrosine phosphatase, Striatum-enriched protein-tyrosine phosphatase, STEP.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PSBE_JASNU
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDPLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GREA_DESVH
Sequence: MSSIPISVEGFKQLEKELDRLKKERPGVIQAIKEAREEGDLSENAGYDAARERQGMLEARIKYIESRMAQFNVIDLDTISGDKVMFGATVKIEDLESGEEKEYTLLGPDEADYAKGSISVQSPVARAMLGKEEGDEIVVDAPRGKIHYEIVSIRFLGTKGQQR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: TUSA_YERPB
Sequence: MTDIFANPDKTLDALGLRCPEPVMMVRKTVRHMEEGQTLLIIADDPATTRDIPGFCRFMDHQLLAQDTEQTPYRYLVRKGITAG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPT2_RAT
Sequence: MPGLWRQRLPSAWALLLLPFLPLLLPAAPAPHRGSYKPVIVVHGLFDSSYSFRHLLDYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMEKAPEGVHLICYSQGGLVCRALLSVMDEHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWHDPHHDDLYLNASSFLALINGERDHPNATAWRKNFLRVGRLVLIGGPDDGVITPWQSSFFGFYDANETVLEMEEQPVYLRDSFGLKTLLARGAIVRCPMAGVSHTTWHSNRTLYDACIEPWLS
What is the function of this protein?
Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA.  Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates.  However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity).
What are the official names of this protein?
Lysosomal thioesterase PPT2, PPT-2.
What is the protein family that this protein belongs to?
Belongs to the palmitoyl-protein thioesterase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PAND_AZOVD
Sequence: MHAIMLKAKLHRAEVTHSVLDYEGSCAIDGEWLDLAGIHEYEQIQIYNVDNGERFTTYAIRAEDGSKMISVNGAAAHKAQKGDRVIICAYAHYSEAELATHKPRMLYMAPGNVLSHTSNAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_LACDA
Sequence: MGSKINPIGFRLGVNRDWEAKWYAARGYKETLNEDLRIRKFLDEKLKDASVSTVEIERAANRVNIAIHTARPGMVIGKGGAEVEALNKEINALTNKQVHINIVEIKKPDLEAKLVADGIARQLEARIAFRRASRQAAQRSMRAGAKGIKVQIAGRLNGADIARREWHTEGSVPLHTLRADIDYAWVNAFTTYGEIGVKVWINRGEILPGRKNQPAKRSKGGKK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NQRF_ACTSZ
Sequence: MDSNFIFGIGAFTAIVLVLAVVILIAKSKLVDSGDITISINDDPSKAITLPAGGKLLGALASKGIFVSSACGGGGSCGQCRVKVKSGGGEILPTELSHISKKEAKEGWRLSCQVNVKSSMDVELPEEVFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFRAGGYIQIEAEPHTVAYKDFDIPEEYHEDWDKFNLWRYVSKVDEHIIRAYSMASYPEEKGIIMLNVRIATPPPRNPNVPPGQMSSYIWSLKPGDKVTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLHSKRKISFWYGARSKREMFYVEDFDQLQAENPNFTWHVALSDPLPEDNWDGYTGFIHNVLYENYLKNHEAPEDCEYYMCGPPVMNAAVIKMLEDLGVEHENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS2_STAA2
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVRKVDEAYNFLKQVSEDGGQVLFVGTKKQAQESVKSEAERAGQFYINQRWLGGLLTNYKTISKRIKRISEIEKMEEDGLFEVLPKKEVVELKKEYDRLIKFLGGIRDMKSMPQALFVVDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMADAILEGQQGVSNEEVAAEQNIDLDEKEKSEETEATEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS16_PSEA8
Sequence: MVTIRLARGGSKKRPFYHLTVTNSRNARDGRFVERIGFFNPVATGGEVRLSVDQERATYWLGQGAQPSERVAQLLKDAAKANA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PI5PA_MOUSE
Sequence: MEGQTRSGSARPGTRTGLGPLPGTHGVLQAEIPSKKVNSSFQLPAKNSGPASSEPRLTLAPVGPRAAVSPPSERPRLVLSSPRPVLAPLSIAGEQKRPPPPHSSNRAAKSVGQLVVSAAAASKPPPVASVSILAPKSLGQLVISASAMPRPSPAPLGSVLTPTSRDQKQLSPTSVGPKPALATSGLSLALASQEQPPQSPSSPSPVPSPVLSPSQEGHLAAASVTSTPASERQLPARQKDTAVPRPTPPADKCLYTPERAAGPATSPPRAQAFSDPRLSPSFRARPEAPRHSPEDPVLPPPPQTLPLDVSPGLPESGTRSPGLLSPTFRPGIPSSQTVPPPLPKPPRSPSRSPSRSPNRSPCLPPAPEVALPKPVTQAAGSGRCPSPNLQAQESPAAATTTTSPTSSWSAQPTCKSDPGFRITVVTWNVGTAMPPDDVTSLLHLGSGHDNDGADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAHGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSNQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPSGGPSPSGRESHRLQVTQHSYRSHMEYTVSDHKPVAAQFILQFAFRDDVPLVRLEVADEWARPEQAVVRYRVETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEEVDGNIYQVTFSEESLPKGHGDFILGYYSHHHSILIGVTEPFQISLPTSESASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPSLALHPSSRERRGGSRSPSPQSRQLPRVAPDRGHSSSSRGSSEEGPSGLPGPWAFPPSVPRSLGLLPALRLETVDPGGGGSWGADQEAPDPNSLSPSPQGRLGLEEGGLGP
What is the function of this protein?
Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate.  Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro.  May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.
What are the official names of this protein?
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, Inositol polyphosphate 5-phosphatase J, Phosphatidylinositol 1,3,4,5-tetrakisphosphate 5-phosphatase, Phosphatidylinositol 1,4,5-trisphosphate 5-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Predominantly localized to membrane ruffles.
Protein: NGB_CHAAC
Sequence: MEKLSEKDKELIRGSWESLGKNKVPHGVVMFSRLFELDPELLTLFHYTTNCGSTQDCLSSPEFLEHVTKVMLVIDAAVSHLDDLPSLEDFLLNLGRKHQAVGVNTQSFAEVGESLLYMLQCSLGQAYTAPLRQAWLNLYSIVVAAMSQGWAKNGEDKAD
What is the function of this protein?
Involved in oxygen transport in the brain.  Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom.  Capable of penetrating cell membranes (By similarity).
What are the official names of this protein?
Neuroglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Perikaryon. Cytoplasm. Note=Located in the soma (perikaryon) of most nerve cells in brain. Has ability to penetrate cell membranes and translocate into cells (By similarity).
Protein: RS11_FLAPJ
Sequence: MAKASTKKRKVIVESIGEAHISATFNNIIISLTNKKGEVVSWSSAGKMGFRGSKKNTPYAAQMAAEDCSKVAMEAGMKKVKVYVKGPGNGRESAIRSLHNAGIEVTEIIDVTPLPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: QUEA_CLOBM
Sequence: MKVKDFDFYLPEELIAQHPMEKRDEARLLVLDKETGEIEHKIFKDILDYLTPNDCLVLNNTRVLPARLIGAKEETGGKMEFLLLKRKEKDVWETLVKPGKRAQIGARFIFGNGELKAEVIGMGEEGSRIVKFYYEGIFEEILDQLGQMPLPPYIKEKLDDKEMYQTVYSKEEGSAAAPTAGLHFTEELLKKIKEKGVKLAFLTLHVGLGTFRPVKVEDIQEHVMHSEYYKMDKETAEIINDTKEKGGRVIAVGTTSCRTLETIGDIEGKVREQSGWTDIFIYPGYKYKVVDALITNFHLPQSTLLMLVSALAGRDNIMNAYNVAVEKEYRFFSFGDAMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T150B_DANRE
Sequence: MWAWALLPVFLAVFGTVGLWAVYAIAVSNNSVNITIEFPYISTCGAYTPQSCLFAQICNICCVLALWIVVIRFQQIRDLGRSSHLNTAGLVLGFISSIGISILGNFQQTIIQEVHLLGALMAFFLGLAYFWIQAFITYFSPPSRDNKWLVPVRFVLCSQCTCMVICMFVLHSTGFRSAAAICEWILVMCFFALFGVFAAEFRHIDFHKLTVQKEGLKVANNDNVVWTVQDVQ
What is the function of this protein?
Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux (By similarity).  Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner (By similarity).  May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival (By similarity).
What are the official names of this protein?
Modulator of macroautophagy TMEM150B, Transmembrane protein 150B.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein.
Protein: SYDND_RHOP2
Sequence: MHRYRTHTCGALRDSDIDQTVRVSGWCHRIRDHGGLLFIDLRDHYGLTQCVADPDSPAFKDAEKLRAEWVVRIDGRVRRRPEGTDNDDLPTGKVEIFITEIEVLGPAGELPLPVFGEQDYPEDVRLRYRFLDLRREKLHQNIMTRGAIVDAMRKRMKEQGFFEFQTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDVEMSFVTQDDVFAAMEPVITGVFEDFAKGKPVTKSWPRIPYFESLRKYGTDKPDLRNPLEMQDVSEHFRGSGFKVFARMLEEERNQVWAIPGPGGGSRAFCDRMNSWAQGEGQPGLGYIMWREGNEGAGPLANNIGPERTEAIRVALGLKAGDAAFFVAGDPAKFVKFAGLARTKVGEELNLIDKDQFALAWVVDFPMYEYNEDDKKVDFSHNPFSMPQGGMDALTSQDPLTIKAFQYDITCNGYEIASGGIRNHRPEAMVKAFEIAGYGEQEVIDRFGGMYRAFQYGAPPHGGMAAGVDRIVMLLCGTNNLREISLFPMNQRAEDLLMGAPSQVAPKQLRELHIRLNLPES
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHW5_SCHPO
Sequence: MNKKDKKFNYIFGSEIVNDVKKRLPYYKSDWIDACHYRVLPACLNIYFSNLLPELAFALDMFAKTNNSFGVNEVLLASVLGSVVFALLSSQPLCIVGVTGPITVFNYTVYDIMHDRGTPYFPFLCWICLWSMIFHFIIAIANGVYFVKHITKFSCEIFGLYVAFIYLEKGVQVLCDQLKYGLTNTFLSITIALLFLMVGWLCDTVGKSSLFSYKVRILLLDYGLVASIIFFSGFQHIGKMREVSLAKLPTTKAFEPTLSRSWFIKFWKIPVGDVFLAIPFSIVLTILFYFDHNVSSVMAQDPSFPLTKPAGFHWDFFLLGITTGVSGILGIPAPNGLIPQAPMHTAALCVKRVDYDEDEIEKTHKEVIDRVVEQRASNFIQGLMTVGTMTGPLLLVLHQIPQCVLAGLFWVMGFSAIFGNGITQNVIWMLSDRKVVSKNHTLNHCSSKRVVWLYTILQLIGFGATFAITQVDKASIGFPIIILLLIPFRTYCMPKWFLEEDLEILDENVGIIAYQKV
What are the official names of this protein?
Putative transporter C543.05c.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: SILD_FORIN
Sequence: MAATSQVLTAIARRLEGKVALITGGASGIGETTAKLFSQHGAKVAIADVQDELGHSVVEAIGTSNSTYIHCDVTNEDGVKNAVDNTVSTYGKLDIMFSNAGISDPNRPRIIDNEKADFERVFSVNVTGVFLCMKHAARVMIPARSGNIISTASLSSTMGGGSSHAYCGSKHAVLGLTRNLAVELGQFGIRVNCLSPFGLPTALGKKFSGIKNEEEFENVINFAGNLKGPKFNVEDVANAALYLASDEAKYVSGHNLFIDGGFSVCNSVIKVFQYPDS
What is the function of this protein?
Oxidoreductase involved in lignan biosynthesis.  Catalyzes the stereospecific conversion of (-)-secoisolariciresinol to (-)-matairesinol via a lactol intermediate.
What are the official names of this protein?
Secoisolariciresinol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PIMT_COLP3
Sequence: MSSRIGGKSKRSGELLAQKLQSEGISNPAVLKAIAHSPRHIFVPEILAHKAYDNTALPIGQGQTISQPYIVAKMSELLLADGRPQNILEIGTGSGYQTAILAQLTDKVFSVERIKALQWQAKRCLRAMDLHNVAMKHGDGWQGWRSKGPFDAIIVTAAPSSVPPALLDQLADGGRLVIPVGEQTQILKIITREGDVYNEQQVEAVRFVPLVPGDLL
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_PSEA6
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLTSVAEQLDEISGGYLSNLLRRGDLEGKPGQMLLLHHVPNVLSERVLLVGCGKERELDERQYKQIISKTIKTLNETGSMEAVCFLSELHVKGRDTYWRVRQAVEATQDSLYTFLQLKTKKGEPRRPLRKMVFNVPTRRELTIGERAVEHGLAVSLGSKTTRDVANMPPNICNPMYLFEQAKALEAEYENLHVDSVNEKQMDALGMHSYLAVGRGSVNESIMTIMEHKGGPADQAPIVLVGKGLTFDSGGISIKPGEAMDEMKYDMGGAAGVLGAMHTISALNLPINVVGILAGCENMPDANAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDALTYVERFDPELVIDVATLTGACVIALGHHATGVFSNHNPLAHELVNASEQSGDKAWRMPLWDEYQDQLESPFADMTNLGGRPAGSITAACFLSRFTRKYNWAHMDIAGTAWVGGKEKGSTGRPVPMLSQFLMNRAGIESED
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRWD1_DICDI
Sequence: MSSKKRSFGDIEFGESDEVGGTNVDVNGEDDFENDDEVESFEDDEQSFEEIEEGGEEGGDNDGEDKGPKKVWRAGVDPLEEDEVLDYDSTAYDMMHSMSVEWPCLSFHPIKDELGAQRNKYPHTMYLVAGTQADEAKNNKVIIMKAKQLHKTKHDDEDSDDDEDSDDDEESDDEDDEDKDVDPELQLAFINHNGAVNRIRSMDQQSNIVATWSDNRSVYIWNIANHLKALDNETVAPKQTAPLHTISNHSIEGYALDWSPKIAGRLATGDCNNSIFVTNASESTWKTDTQAFKGHTESVEDIQWSPSEEKVFASCSIDQTVRIWDIRKPKPAITVKAHTADVNVISWSRNVEYLLVSGCDDGSFRVWDLRAFKDNSPVSDFKYHTGPITSIEWNPYEESQVIVSSSDDQVTIWDFSLEEDTEEFTNANANPDDDFQYPPQLFFIHQGQHDIKEVHWHPQIPHVAISTSIDGFNIFKSSNSEE
What are the official names of this protein?
Glutamate-rich WD repeat-containing protein 1.
What are the subcellular locations of this protein?
Nucleus, nucleolus.