PharMolix/UniProtQA huggingface dataset:
Protein: MYOM3_MOUSE
Sequence: MTLPHSPGSAGEPQASQTVQVHRLEHRQEEEQKEERQHSLQMGSSVQRRTYRSSEEEQQFSSEDYALAAALALTASSELSWEAKLRRQTTTVELEERGQRRVGFGNDLERMELAFLRTQRLLRQRRDWKALRQRTEEKVREAKELIELCSGRGPWFWIPLRSHAVWEHTTVLLTCTVQGSPPFQVTWYKNDIRIDPRLFPAGKYRITNNYGLLTLEIMRCTVEDSATYTVLVKNAYGQASSFAKVLIRNYLGKDAGFDSEIFKRSMFGPSAEFTSVLKPIFAQEKEPFSLTCLFSDDVLEAEQRIQWYRDGRLLRSSTRRQILYADRQASVKVSCAYKEDEGFYTIRVSSPFGPQEQSAYVFIRDAAAEKPGAPGSPLNVRCLNVHRDCLTLTWVPPSDTRGSTITGYSIEMCQGDSEEWMPCLKAPGGTCRCPIQGLVEGQSYQFRVRAISKAGTSLPSKASEAVVTGDYDAVHKSTEIPYDLGSKITISKNDFEDAVTIPSAPTNVHASEIREAYAVLSWEEPRPRGRAPLTYTLEKSVIGSGTWEAISTETPIKSPRFALLDLEKGKSYVFRVRALNQYGMSDPSEPSEPVALKGKPATLPPPAQVQAFRNTQTSVSLAWEPVDGGSELLGYYIYSREAGASEWQTVNNKPIQDTKFTVPGLRTGKEYDFCIRSVSEAGVGESSAATQPVRVKQALATPSAPYDFALLNCGKNEMVIGWKPPKRRGGGKILGYFMDQHDSVESDWHPVNRQPIPSRVCKVTNLHEGHFYEFRARAVNWAGIGELSAPSSLFECKEWTMPEPGPPYDVRVSEVQATSVMLQWEPPLYIGAGPVTGYHVSFQEKGSEEWKPVTPDATSDTHLRVSDLQPGKQYMFRVQAMNSAGLGQPSVPTDPVLLEDKPDAQEIEVGVDDEGQIYLAFEAPEAPDFPEFQWSKDYQGPPDPQRVEVEDEISKSKVILKEPDLQDLGIYSVVVPDADEDTSASHTLTEEELNKLKKLSHEIRNPVIKLISGWNVEILEQGEVRLWLEVEKLSPAAELHLIFNEKEIFSSPNRKINFDREKGLVEVIIQQLSEDDKGSYTAQLQDGKAKNQITLALVDDEFDKLLRKADAKRRDWKRKQGPYFQEPLTWKVTDDCQVLLSCKVTNTKKESRFQWFFQKKEAPHGQYNPPTGDGSLSIEGFSKENQGVYRAVVSDERGEDDTVLDLTGEALDAVLTELGRIGALSATPLKIQGTEEGIRLFSKVKYYNVDYMKTAWFHKDKRLESGDRVRAGTTLDEIWLHILDPKDSDKGKYTLEITAGKEVRQLSADLSGQAFDDALAEHQRLKALAVIEKNRAKVVRGLPDVATIMEDKTLCLTCVISGDPSPEISWLKNDQPISFFDRYHMEVKGTEVTVTIDKVTSEDSGRYGIFVKNKYGSETGQVTISVFKHGEEPKELKKK
What is the function of this protein?
May link the intermediate filament cytoskeleton to the M-disk of the myofibrils in striated muscle.
What are the official names of this protein?
Myomesin-3, Myomesin family member 3.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, M line.
Protein: AROL_SALTI
Sequence: MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEADLRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKAPAQVVSEIIAALPPSTQRLQGDVYT
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_ZYMTR
Sequence: MRIWKSHPLFSLVNGYLIDSPQPSNLSYLWNFGSLLGFCLVIQIVTGVTLAMHYNPSVSEAFNSVEHIMRDVNNGWLIRYLHSNTASAFFFLVYLHVGRGLYYGSYKAPRTLTWTIGTIILVLMMATAFLGYVLPYGQMSLWGATVITNLLSAIPWVGQDIVEFVWGGFSVNNATLNRFFALHFVLPFVLAALVLMHLIALHDTAGSGNPLGVSGNYDRLPFAPYFIFKDLITIFLFIIVLSIFIFFMPNVLGDSENYVMANPMQTPPAIVPEWYLLPFYAILRSIPNKLLGVIAMFSAILIIMIMPITDLGRSRGLQFRPLSKITFYIFVANFLVLMQLGANHVESPFIEFGQISTVLYFSHFLIIVPLVSLIENTLVDMHLNNTIT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSBF_GUNCH
Sequence: MTIDRTFPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PURA_AGRVS
Sequence: MTNVVVVGSQWGDEGKGKIVDWLSERADVVVRFQGGHNAGHTLVIDGISYKLSLLPSGVVRPGKMAVIGNGVVVDPHALIAEIAKLAAQGVTVTPDNLRIADNATLILSLHRELDGMREDAATNSGTKIGTTRRGIGPAYEDKVGRRAIRVMDLADPEGLAEKVARILPHHNALRRGFGAPEVEHSTIMEELLSVADKVLPFRETVWLMLDKERRRGARILFEGAQGSLLDIDHGTYPFVTSSNTVAGQAAAGSGMGPGSLGYILGITKAYTTRVGEGPFPTELTDEVGQFLGEKGHEFGTVTGRKRRCGWFDAALVRQSVATNGITGIALTKLDVLDGLDELKICVGYKLDGVEIDHLPAAQAAQARVEPIYVTLEGWKESTVGARKWADLPAQAIKYVRQVEELIGAPVALLSTSPERDDTILVTDPFED
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDC_YERPB
Sequence: MELQLTGKESGWWIVSHENKLWLPKGELPQGNAANWSLQGATARQIGEWQGQPVWLIRQMMPSGMGSVRQLLDVDRGLFQLAGRGVQLAEFYRSHRFCGYCGHEMHASRTEWASLCNHCRERYYPQIAPCVIVAIRRGDEILLAQHVRHRGGINTVLAGFVEVGETLEQAVSREVLEESNIHIKNLRYVTSQPWPFPHSLMMAFMADYDSGELCHDPKELLNAGWYRYDQLPLLPPPGTVARRLIEDTVVLCREHSDLSQ
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: ATPG3_ARATH
Sequence: MAMAVFRREGRRLLPSIAARPIAAIRSPLSSDQEEGLLGVRSISTQVVRNRMKSVKNIQKITKAMKMVAASKLRAVQGRAENSRGLWQPFTALLGDNPSIDVKKSVVVTLSSDKGLCGGINSTVVKVSRALYKLNAGPEKEVQFVIVGEKAKAIMFRDSKNDIVLSVTELNKNPLNYAQVSVLADDILKNVEFDALRIVYNKFHSVVAFLPTVSTVLSPEIIEKESEIGGKLGELDSYEIEGGETKGEILQNLAEFQFSCVMFNAVLENACSEMGARMSAMDSSSRNAGEMLDRLTLTYNRTRQASITTELIEIISGASALEAAK
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and the central stalk which is part of the complex rotary element.  The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit gamma, mitochondrial, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein.
Protein: FTSB_XYLFM
Sequence: MRNWRWLLLVLAALLAWLQHRFWFGPGNSGEVRMLQVQIVQQHQENERLRQRNASLAAEVKNLKDGDAAIEERARSELGMIKPGEIFYRVVEDIPAPLPNDTSADHGVDLSQPRREKR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: DAPD_BURM1
Sequence: MSQQLQQIIDNAWENRAELSPKAAPAEVREAVAHAIEQLDKGALRVAEKIDGNWTVHQWLKKAVLLSFRLEDNAPMPAGGYSQFYDKVPSKFANYTAEDFAAGGFRVVPPAIARRGSFIAKNVVLMPSYTNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEISYGRIPAGSVVVAGNLPSKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MYOME
Sequence: MINLRKTHPLLKIINHAFIDLPTPSNISAWWNFGSLLGMCLMIQILTGLFLAMHYTSDTMTAFSSVAHICRDVNYGWLLRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLAEWIWGGFAVDKATLTRFFAFHFILPFIITALAMVHLLFLHETGSNNPTGINPNADKIPFHPYYTIKDALGLTFLFLVLLLLALFSPDMLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASIMILLILPLLHTANQRSMMFRPISQTLFWILTADLITLTWIGGQPVEQPFIIIGQLASMLYLLLILVLMPLAGLLENYMMKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATPB_CAEEL
Sequence: MASRSLASISRSASRLLQSNVQKCALPAASIRLSSNNVESKKGIHTGVATQQAAAATKVSAKATAANASGRIVAVIGAVVDVQFDENLPPILNGLEVVGRSPRLILEVSQHLGDNVVRCIAMDGTEGLVRGQPVADTGDPIKIPVGPETLGRIMNVIGEPIDERGPIASKNFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVIDLKGKNSKVSLVYGQMNEPPGARARVCLTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGSMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIAELAIYPAVDPLDSTSRIMDPNVVGQNHYDIARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHQGKFVSLEETIRGFTMILKGELDHLPEVAFYMQGGIDDVFKKAEELAKQHGN
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (Probable).  Required during male mating behavior for the response to hermaphrodite contact, acting with lov-1 and pkd-2.  May be involved in polycystin signaling.
What are the official names of this protein?
ATP synthase subunit beta, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell projection, cilium. Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein. Localizes to the cilium only in male-specific sensory neurons.
Protein: LFTR_SHIFL
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_CROS8
Sequence: MSNRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPASQVYDLGCSLGAATLSVRRNVHHDGCKIIAVDNSPAMVERCRRHIDAFKAQTPVEVIEDDIRNITIENASMVVLNFTLQFLNPDDRQLLLNKIFQGLNPGGALVLSEKFSFEDSVVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLRKAGFEHSELWFQCFNFGSLVAVKGGSAT
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: HRI1_YEASA
Sequence: MPALLKRLLFQVGPHPNERTFTLSSVSTDGHYISLRPFVKPSGDELSFPFEWAFAGTNETVKVNDQGNGVVTQDFNFWLDTNVYLNVPNTHRGEVNTTWKNWDSGCVEETGAVYPFGADKESVSFRELWQPVDPSREDLVIVSPNNEKFSSNARSIVLKVTDEAYDGLVIVIGRWIQXVFVPKE
What are the official names of this protein?
Protein HRI1, HRR25-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the HRI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DHAS_PROMA
Sequence: MTLQKPFPDRPLTLAVLGSSGAVGAEILKILEERSFPIRELRLLASERSAGQVQFFKGEDLVVKKVSPEGFEDVDLVLASAGGSISRKWRKVINSAGAVIVDNSNAYRMEPDVPLVVPEVNPSQVFTHKGLIANPNCTTILLALVLAPLSAQLPIKRVVVSTYQSASGAGARAMNELKQLSQDVLNGNIPKSEILPYSLAFNLFLHNSPLQSNNYCEEEMKMINETRKILNQSELAITATCVRVPVLRAHSESINIEFAEPFPVEEARKILSNASGIKLLEDIQMNRFPMPIDVTGKDDIAVGRIRQDLSNPKALELWLCGDQIRKGAALNAIQIAELLLTRS
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: H4_DROHY
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MED12_PANTR
Sequence: MRAAWLIKMTCAYYAAISETKVKKRHVDPFMEWTQIITKYLWEQLQKMAEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSENERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPADDAEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEGTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVTGGTEELPEEEGGGGSGGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLENIAKATIEVFQQSAETGSSSGSTASNMPSSSKTKPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGERQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQAKIQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12, Trinucleotide repeat-containing gene 11 protein.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS8_NEIMA
Sequence: MSMHDPISDMLTRIRNAQRANKAAVAMPSSKLKCAIAKVLKEEGYIEDFAVSSDVKSILEIQLKYYAGRPVIEQIKRVSRPGLRIYKASSEIPSVMNGLGIAIVSTSKGVMTDRKARSQGVGGELLCIVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TPMT_RABIT
Sequence: MDDARTLLDIKEYPDTEVQKNRVLTLEEWQDKWVSHKIGFHQEQGHKLLKKHLDAFLKGESGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIREFFSEQNLSYSEEPITEVPGAKVFKSSAGNISLYCCSIFDLPRVNIGKFDRIWDRGALVAVNPSDRKRYAAVMLSLLRKGFQYLLAVLSYDPTKHAGPPFYVPDAEIKMLFDTKCKIHCLEKVDAFEERHKSWGIDYIFEKLYLLTEK
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAMM_MAGGM
Sequence: MRKSGCAVCSRSIGWVGLAVSTVLMVMKAFVGLIGGSQAMLADAMYSLKDMLNALMVIIGTTISSKPLDAEHPYGHGKVEFILSMVVSVVFIVLTGYLLVHAVQILLDESLHRTPHLIVLWAALVSIGVNVGMYFYSRCVAIETNSPLIKTMAKHHHGDATASGAVALGIIGAHYLNMPWIDPAVALWETIDLLLLGKVVFMDAYRGLMDHTAGEAVQNRIVEAAERVPGVRGVIHLRARYVGQDIWADMIIGVDPENTVEQAHEICEAVQAAVCGKIRRIESLHVSAEAREIGDTTKPSFSDQPLSFDEVMLSKVDN
What is the function of this protein?
Essential for magnetosome formation; required for stable accumulation of MamB (PubMed:22007638).  May nucleate iron crystal formation (Probable).  Probably binds and transports iron.  Binds divalent cations, possibly up to 3 Zn(2+) per dimer in vitro, probably iron in vivo (Probable) (PubMed:30811856).  One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamLQRBIEMO in a deletion of the 17 gene mamAB operon restores magnetosome vesicle formation but not magnetite biosynthesis (PubMed:27286560).
What are the official names of this protein?
Magnetosome protein MamM, Probable iron transporter MamM.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
What are the subcellular locations of this protein?
Magnetosome membrane; Multi-pass membrane protein. Cell inner membrane; Multi-pass membrane protein. Note=Localizes with magnetosomes in a straight line running through the center of the cell.
Protein: HMT_BACSU
Sequence: MNPIQHILDTYPLIVLDGAMATELERKGCNLNDSLWSAKILMEEPELIKQVHTDYFAAGADCAITASYQSTFEGFAARGLSEAEARRLIELSVSIAAEARDEFWSLEENRLNRPKPIIAASIGPYGAYLADGSEYRGNYAISEDELIEFHRPRMKALIEAGADVLACETIPCLTEAKAIVRLLKEFPETYAWISFSAKDGLHISDGTPAADCASWLDEHRQIAALGINCTPLQHIPSLIEELKKNTSKPIIVYPNSGEQYDPETKTWNGAACAESYGASARTWHEKGARLIGGCCRTKPENIQEIAAWARSLKTT
What are the official names of this protein?
Homocysteine S-methyltransferase YbgG, S-methylmethionine:homocysteine methyltransferase.
Protein: SPEA_VIBPA
Sequence: MRIELEKATKLDRIRADYNVHYWSQGFYGIDDQGEVYVSPRSDRAHQIPFSAIVNELEAQQLNLPVLVRFPQIVHQRVHGICHAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQAQLETKQLGLEAGSKPELLAVLALAQQGSSVIVCNGYKDREYVRLALIGEKLGHKVFIVLEKLSELDLVLEEAKSLGVKPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLSVIERLKREGSLDAMQLVHFHLGSQMANIRDVRNGVNESARFYCELRALGANIEYFDVGGGLAVDYDGTRSQSSNSMNYGLAEYARNIVNTVGDVCQQYEQPMPVIISESGRSLTAHHAVLISNVIGTETYQPEEVHELGVDAPLLLQNMWRNWENLQDGTDARALIEIYNDTQSDLAEVHSQFATGVLNLEQRAWAEQLSLRIYFELSRKMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPDAWGIDQVFPVLPLSGLGDAEERRAVMLDITCDSDGAIDHYVDGQGIESTLPVPAWSKDKPYLMGFFLVGAYQEILGDMHNLFGDTHSAVVNVDEHGQFEISYINEGDSVEDMMRYVHIDVDAIRDNYKQLVSQRVEANEQAQILAELEQGLAGYTYLEDF
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: TKT1_YEAST
Sequence: MTQFTDIDKLAVSTIRILAVDTVSKANSGHPGAPLGMAPAAHVLWSQMRMNPTNPDWINRDRFVLSNGHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLIAIYDDNKITIDGATSISFDEDVAKRYEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKDKPTLIKMTTTIGYGSLHAGSHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPGVEANNKWNKLFSEYQKKFPELGAELARRLSGQLPANWESKLPTYTAKDSAVATRKLSETVLEDVYNQLPELIGGSADLTPSNLTRWKEALDFQPPSSGSGNYSGRYIRYGIREHAMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLSALSGHPVIWVATHDSIGVGEDGPTHQPIETLAHFRSLPNIQVWRPADGNEVSAAYKNSLESKHTPSIIALSRQNLPQLEGSSIESASKGGYVLQDVANPDIILVATGSEVSLSVEAAKTLAAKNIKARVVSLPDFFTFDKQPLEYRLSVLPDNVPIMSVEVLATTCWGKYAHQSFGIDRFGASGKAPEVFKFFGFTPEGVAERAQKTIAFYKGDKLISPLKKAF
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 1, TK 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.