PharMolix/UniProtQA huggingface dataset:
Protein: GIMA8_MOUSE
Sequence: MATSSHQGAAAGSQAEHRSCEASVGQGERPSASQGQEGNFKQNQGTSTLRLLLLGKQGAGKSATGNTILGKAVFESKFSDHMVTDRCQSESVSVRGKQVIVIDTPDLFSSLSCSEVRQQNLKQCLELLADDHCVLLLVTPIGHYTEEDRETIEGIWGKIGPKAYRHMIVVFTREDELDEDSLWNYIESKESLKELIKNIGSRRCCTFNNKADKKQRELQVFKLLDAIELLMMESPEPYFEPLKMESSGVQGCGNGVTYEGDTLCGSKKRQPQITGPDCDPDMPELRVLLMGKRGVGKSAAGNSILGKQVFKTQFSEKQRVTKAFASHSRVWQGKKVLIIDSPEISSWKLDESAVKNHTFPGPHAFLLVTPLGSSLKSDDDVFSIIKRIFGEKFTKFTIVLFTRKEDFEDQALDKVIKENDALYNLTQKFGERYAIFNYRASVEEEQSQVGKLLSQIEKMVQCHSNKPCVIREKELLNIILLGRSGAGKSATGNTILGRSAFFSQLRAQPVTSSSQSGKRTLDWQDVVVVDTPSFIQTPGTEKDPSRLKEEIHHCLSLCEEGMKIFVLVLQLGRFTQEDEVVVEQLEASFEENIMKYMIVLFTRKEDLGDGDLHDYTNNTKNKALKKILKKCNGRVCAFNNKETGEDQETQVKGLLKIANSLKKNYDEHSNSWVGQLKSTLGQITMAFK
What is the function of this protein?
Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections.
What are the official names of this protein?
GTPase IMAP family member 8, mGIMAP8, Immune-associated nucleotide-binding protein 9, IAN-9, Immunity-associated protein 8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Mitochondrion. Cytoplasm, cytosol.
Protein: LPTD_ACISJ
Sequence: MDRLPLPHALHVPTHRPFAAPLPPRRLLARLAALMLCGVPLAVLAQAQPSQDAAPAEPPPALRSSPRLQEVLPYGIRQQLPVFVRGDRVTGQPDIQATIEGNAELRRGDTVVHADRMQYDVADDRARASGNVLINRAGNRYEGSQLDLRVEAFTGFFSDARYRFLETAAHGQASRVDFLDRDRSVVHNATYTTCERTDEASWQPDWILRAERIHLDRVEDVGTAENGVLEFKGVPVLPIPRITFPLSDRRKSGLLPPTLGLDSVSGFEYAQPYYWNIAPNRDATITPTVMTRRGVALGTEFRYLEPRYSGELTADYMPNDRLRDRDRWAYGIKHRATFDTPAGGVGLGIDIKRVSDDNYWRDFSQRNSGRSGVNDQLTQRLLPGDATLNWARGEHSLLLRTLKWQTLQDVNAPIIPPYDRMPQLRWEYRPLQLAGGLDASVEADYTSFHADRAYTGQPNAKRSYTMAQVSRPFLAPAGFITPRVQLHSTHYEFDAPLANGQRTASRTLPTFSLDSGLVFERDARYFGRDFLQTLEPRAFYTYTPYRDQRLLPIYDTAVNDFNFASIYTENAFGGQDRLADNNLLTLGVTTRLLDPDTGAEAARFGVAQRVRFSDQEVTMPGGSPVNERLSDVLLGAGINWTPQWGFDSTVQYNPKTGRSLRTTVGARYSPGNYRTVSAAYRMQKVTGLITEPSEQIDVGWQWPLNDLWGDRGDKPSSAGGRWYSVGRLNYSLQDRKLVDTVVGLEYESCCWIGRVVLERLQRSVTSSNTRLMFQIEFIGFSRLSLGSNPLSSLKQNVPRYQFLRESVSTPSRFTQYD
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: MUL1_XENLA
Sequence: MENGGRPSVGQVILLTTSSAITALFYSIYRHKYRSVQTLKEAKKFCLTDDLPAVLSDLPGKCVPYAVIEGAVTSVKEVLNSQYVENCKGVIQRLSLKEHKMVWNRTTHLWNDHEKIIHQRSNTVPFDLAPENPGESGVSVRVLRPLEAVDLGLETIYEKFHPAVQSFSNILGHYMTGERPKGVQETEEMLKIGATITGVGELVLDNKTIKLQPPKDGMLFYLSSMDYEGLLEKQEVQMRWWRILSIVFGVASCITLFFILRRKYRHYKEKQHLKNLQREFEESRARQRVQQEPQNKEEVQNPCSICLSTEKSCVFLECGHVCSCISCYQALPSPKKCPICRNFIDRIVPLYNS
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology.  Promotes mitochondrial fragmentation and influences mitochondrial localization.  Inhibits cell growth.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
What are the official names of this protein?
Mitochondrial ubiquitin ligase activator of nfkb 1, E3 ubiquitin-protein ligase mul1, RING-type E3 ubiquitin transferase nfkb 1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: CNRH_CUPMC
Sequence: MNPEDADRILAAQAASGNQRAFGQLVARHGVALAQAARSFGIPETDVDDVVQDTFVAAWHALDDFDPDRPFRAWLFRIGLNKMRDLYRFRRVRQFLFGAENLGDLELAGGVANDEPGPEQQVAARLELARVASTLGKLDTGSREVIVLTAIVGMSQPEAAAVLGLSVKAVEGRIGRARAKLSALLDADSEK
What is the function of this protein?
CnrH alone is able to activate CNR expression, while both CnrY and CrnX are needed for nickel induction of cnrH (PubMed:10671463).  Binds DNA in an RNA polymerase-dependent fashion (PubMed:10671464).  CnrH may be controlled by a CnrYX transmembrane anti-sigma factor complex which binds CnrH in the absence of Ni(2+).  If Ni(2+) appears in the periplasm, it may be bound by CnrR (CnrX); the signal then would be transmitted by CnrY into the cytoplasm and CnrH would be released.
What are the official names of this protein?
RNA polymerase sigma factor CnrH.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: BPHC1_RHOGO
Sequence: MSVQRLGYLGIEVSDVDAWRTYATMRLGAMEAPAPEGTARFRLDSRAWRFMVTPGPADDLSVAGYEVDSEGALMQVKTRLEAYGVKVTSESSELAAERGVLGLISCVDPAGTRLEIYYGGTEMFEVPFASPTGVKEFRTDDQGMGHYVLAVPDVDAALDFYVQGLGFHLSDVIDWQVSPEVSVRLHFLHCNGRHHTLAVVGMPSDKKMHHLMIETTNLDDVGLAYDRCVEDDAVILTLGRHTNDHMVSFYGATPSGFAVEFGWGSRVVEPGWSVVRYDAISIWGHKIMRGE
What are the official names of this protein?
Biphenyl-2,3-diol 1,2-dioxygenase 1, 2,3-dihydroxybiphenyl dioxygenase I, DHBD I, 23OHBP oxygenase I, Biphenyl-2,3-diol 1,2-dioxygenase I.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: TS1_PENEN
Sequence: MTRMKNSSSNVTSASGSGSGSGGFVQPLPASLLQPICHPRVTEVTSEVNDYFLTHWDFPSEKLRKKFVAADFPGVTCLYFPNALDDRISFACRLLTVLFLIDDLLEFMSLEQGSAYNEKLIPISRGDVLPDRSVPVEYITYDLWESMRGHDRSMANEILEPVFVFMRAQTDRTRIRPMGLGSYLEYRERDVGKALLAALMRFSMALHVSPVELTILGEIDVNCSKHLSVINDVYSYEKELRASKTAHAEGGALCTSVRILADEMAISIEAAKRVLVFMCREWELRHQVLVEELRADGRQSASLTAYVKGLEFQMSGNEEWSKTTLRYNNVV
What is the function of this protein?
Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene (PubMed:35506591).  Aristolochene is the likely parent compound for a number of sesquiterpenoid toxins produced by filamentous fungi (By similarity).
What are the official names of this protein?
(+)-aristolochene synthase TS1, Sesquiterpene synthase TS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: FUCM_MOUSE
Sequence: MVALKGIPKVLSPELLFALARMGHGDEIVLADANFPTSSICQCGPVEIRADGLDIPQLLEAVLRLLPLDTYVESPAAVMDLVPSDKEKGLQTPIWKRYESLLLEADCKKTLMKLERFEFYERAKKAFAVVATGEMALYGNIILKKGTLDLGPS
What is the function of this protein?
Involved in the interconversion between alpha- and beta-L-fucoses.  L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29. 5%) and beta-L-fucose (70. 5%), the beta-form is metabolized through the salvage pathway.  GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases.  Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes.
What are the official names of this protein?
Fucose mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family.
Protein: PRHF_PENBI
Sequence: MSQATVEEKSKLRVIIVGGSVAGLTLAHCLAKANIDHIVLEKRAEISPQEGAFIGIWPNGARILDQLGLYDDFESLMPPVHRMNVRFPDGFTFSSFLPRTIQERFGYPIISIDRQKVLETLYERYPHKSNVLVNKKVMNVRLLGKGVSVVTEDGSAYNGDIVVGADGIHSRIRSEMWRLADENHPGLITSEDKQAFTVEYACVFGISEQLPSLRAGEHINSYSNGLCVITFHGEKGRIFWFLLVKLPKKTTYPNTPRFSAGDAASVCNNFATFRVSEDVCVSDLWMHKLCASMTALEEGILERWHYDRIVLLGDSVHKMTPNIGQGANTALEDASVLASLLNNLSKLSTEDGTSAYAMTKLLDEFQSTRYERAKNTHDKSRFGARLHTRDDMIKTLIGRYVFPYAGPRVLERSVKSLATAHSVEYLPFSKRLGPAWGEYSSRTKSTLGSTPIQMLTLLLPCLFYFMYSKLNLSLSS
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture (PubMed:27602587).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase prhL (By similarity).  Synthesis of DMOA is followed by farnesylation by the prenyltransferase prhE, methylesterification by the methyl-transferase prhM, epoxidation of the prenyl chain by the flavin-dependent monooxygenase prhF, and cyclization of the farnesyl moiety by the terpene cyclase prhH, to yield the tetracyclic intermediate, protoaustinoid A (By similarity).  The short chain dehydrogenase prhI then oxidizes the C-3 alcohol group of the terpene cyclase product to transform protoaustinoid A into protoaustinoid B (PubMed:27602587).  The FAD-binding monooxygenase prhJ catalyzes the oxidation of protoaustinoid B into preaustinoid A which is further oxidized into preaustinoid A1 by FAD-binding monooxygenase phrK (PubMed:27602587).  Finally, prhA leads to berkeleydione via the berkeleyone B intermediate (PubMed:27602587, PubMed:29317628).  PrhA is a multifunctional dioxygenase that first desaturates at C5-C6 to form berkeleyone B, followed by rearrangement of the A/B-ring to form the cycloheptadiene moiety in berkeleydione (PubMed:27602587, PubMed:29317628).  Berkeleydione serves as the key intermediate for the biosynthesis of paraherquonin as well as many other meroterpenoids (Probable).  The cytochrome P450 monooxygenases prhB, prhD, and prhN, as well as the isomerase prhC, are probably involved in the late stage of paraherquonin biosynthesis, after the production of berkeleydione (Probable).  Especially prhC might be a multifunctional enzyme that catalyzes the D-ring expansion via intramolecular methoxy rearrangement, as well as the hydrolysis of the expanded D-ring (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase prhF, Paraherquonin biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YOBH_ECOUT
Sequence: MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLTARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG
What are the official names of this protein?
Uncharacterized protein YobH.
Protein: SELA_PEPAC
Sequence: MDKRTLFSKLPSVDKILGNDGVIELEKEYPRSLIVEVIREQIELARKRILELNESDMEGFDIDEDILINDIGHQLKLKYALKLKRLINATGVVVHTNLGRSPMAEEIKEDLWLIASRYSNLEYDIESGKRGSRYSHLEEIVRKITGAEDVLVVNNNAAAVMLVLGTMAQGKEVITSRGELVEIGGSFRIPSVMEQSGAKLVEVGTTNKTYASDYEAAITENTGALLKVHTSNFRVVGFTNTPELEELREIGDKYDIPVIEDLGSGVFIDLSKYGLSYEPTVMDSLRKGADIVTFSGDKILGGPQAGIIVGKKKYIDKMKKNQLTRALRVDKFIICALEATMRYYIEEEIAIKKIPTLRMLTYKLDEIKEKAQRLNEMIGRLGIPAEVKIEVGHSQVGGGLLPLERIESRVISIVPENMSVSRLEESLRLCDDHIIGRVYDEKYVIDVRTLFDEEYEIICNQLKSILG
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLUQ_BURO1
Sequence: MNPGYRGRFAPSPTGPLHFGSLVGALASWLDARAHGGVWLVRIEDLDGPRTVPGAADDILATLAHFGMTPDEPPVWQSTRDAAYTAALERLVAAGLVYPCGCTRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGCDAVITFDDRWQHTQSQNLATEVGDFVLKRADGQWAYQLAVVVDDADAGITHVVRGADLLDSTARQIYLQRCLGVPTPEYLHVPVVVDANGEKLSKQTGATALERNDPLPALQAAAAHLGLANDGDLPGGTLDAFYAAATDAWARRFGPRAG
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: HEM3_VESOH
Sequence: MNKTLKIATRQSPLALWQAQHVKSRLEKIYPNLTVILVKITTKGDQILNSSLSKIGGKGLFIKELEISIMKGMSDIAVHSMKDVPYEIPQEFELGAILKCENPFDAFVSNHFSSIDDLPKNAKVGTCSMRRILQLKVIRPDLQIIDLRGNVNTRLKKLDDGEFDAIILACAGLIRLGFGNRIKQQIPENQNLPAVGQGAIGIEIRENDKEILDLIKPLIDIETSYRIIAERAMNTQLEGGCSVPVAGFATINNKQITLTGLVGNIDTGVILKEKIFGHVSQAEILGIELANKLILLGAKDILKD
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PUB15_ARATH
Sequence: MVDVMDTDEEATGDAENRDEEVTAEEPIHDEVVDAVEIHEEEVKEDDDDCEGLVSDIVSIVEFLDQINGYRRTQQKECFNLVRRLKILIPFLDEIRGFESPSCKHFLNRLRKVFLAAKKLLETCSNGSKIYMALDGETMMTRFHSIYEKLNRVLVKAPFDELMISGDAKDEIDSLCKQLKKAKRRTDTQDIELAVDMMVVFSKTDPRNADSAIIERLAKKLELQTIDDLKTETIAIQSLIQDKGGLNIETKQHIIELLNKFKKLQGLEATDILYQPVINKAITKSTSLILPHEFLCPITLEIMLDPVIIATGQTYEKESIQKWFDAGHKTCPKTRQELDHLSLAPNFALKNLIMQWCEKNNFKIPEKEVSPDSQNEQKDEVSLLVEALSSSQLEEQRRSVKQMRLLARENPENRVLIANAGAIPLLVQLLSYPDSGIQENAVTTLLNLSIDEVNKKLISNEGAIPNIIEILENGNREARENSAAALFSLSMLDENKVTIGLSNGIPPLVDLLQHGTLRGKKDALTALFNLSLNSANKGRAIDAGIVQPLLNLLKDKNLGMIDEALSILLLLASHPEGRQAIGQLSFIETLVEFIRQGTPKNKECATSVLLELGSNNSSFILAALQFGVYEYLVEITTSGTNRAQRKANALIQLISKSEQI
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
U-box domain-containing protein 15, Plant U-box protein 15, RING-type E3 ubiquitin transferase PUB15.
Protein: GATC_MYCLB
Sequence: MSPISRDEVLHLARLTRLVLTDTELASFSSQLDVILAHVSQIQAVDVTGVEPTDNPLKYVNITRPDETVPCLTQQQALAEAPEAIYGRFVVPQILGDNK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RNH2_ALIF1
Sequence: MTKKAESKELPPFEYPEGYQLFAGVDEVGRGPLVGAVVTAAVILDPNNPIEGLTDSKKLTDKKRELLFPEIQEKALAWSLGRCEAHEIDELNILQATMVAMQRAIAGLNITPDFALIDGNKVPELPMAGLAVVKGDLRVQEISAASIIAKVTRDREMEELDKAYPQYGFAKHKGYPTKAHFEAIEEHGVISEHRRSFKPVKRVLGIE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGHR_ECOLI
Sequence: MDALQTQTVNSTTAPQPNYIPGLIAVVGCDGTGKSTLTTDLVKSLQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLAAKSSKTQSMKTKSPALWAAVIMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFYYDGPGIGVERATGKISMFLAQRERRLYQQMAQYRPELIIRLGIDIETAISRKPDHDYAELQDKIGVMSKIGYNGTKILEIDSRAPYSEVLEQAQKAVSLVAIVSDRRSLT
What are the official names of this protein?
Uncharacterized ATP-binding protein YghR.
What is the protein family that this protein belongs to?
To E.coli YghS and YghT.
Protein: MURE_RICFE
Sequence: MPYNLKQLFQKHNVKGLSINSKTVKENDIFFAIKGQNVDGNDFINEVLNQAVALVITDNKKNTIIDDKVIYVEDVQVALYEAIEIFYPKKPKNLIAVTGTNGKSSVVSYIAQTYSLLGKKAASIGTIGVEIFGCDNLINDVPELTTLDYLSFRKIAHNLAENNIEYLAFEASSHGLNQARLGEIKVNTACFTSFSQDHLDYHHTKENYLLAKLKLFTRHLFKPAYREEFKGDTEHSTTAYILVREDASTGSTSKLLLEAKFGKMSTEYLLQGGLAILNSDIAEIEFVKDYLRNHNIKFITVGKKGDVQITKINGSLKAQNINFIFNNRECSFNTSIIGSFQASNLLIAALSIHYIGFDFNKIIEILTQVKPVKGRMERIGNTNIFVDYSHTPDALEKALTELKNVKLRDSRLNVVFGCGGNRDKTKRSLMGQIAARLADNVIITDDNPRHEDPKLIRAEIISGIEKADYTEIANREEAIKYGINNLKQDDILLIAGKGHENYQIIGDKKLPFDDAEIVRKLMSLRGKAKP
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SO4A1_HUMAN
Sequence: MPLHQLGDKPLTFPSPNSAMENGLDHTPPSRRASPGTPLSPGSLRSAAHSPLDTSKQPLCQLWAEKHGARGTHEVRYVSAGQSVACGWWAFAPPCLQVLNTPKGILFFLCAAAFLQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGVRTCPANPGAVCADSTSGLSRYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIAIFYTAAILGPAAGYLIGGALLNIYTEMGRRTELTTESPLWVGAWWVGFLGSGAAAFFTAVPILGYPRQLPGSQRYAVMRAAEMHQLKDSSRGEASNPDFGKTIRDLPLSIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFCLFCTVVSLLGILVFSLHCPSVPMAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIPQNLSSGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAMSRYILIMGLLYKVLGVLFFAIACFLYKPLSESSDGLETCLPSQSSAPDSATDSQLQSSV
What is the function of this protein?
Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, taurocholate, estrone 3-sulfate, estradiol-17beta-glucuronide and prostaglandin E2 (PGE2) (PubMed:10873595, PubMed:19129463).  Shows a pH-sensitive substrate specificity T4 and estrone 3-sulfate which may be ascribed to the protonation state of the binding site and leads to a stimulation of substrate transport in an acidic microenvironment (PubMed:19129463).  Hydrogencarbonate/HCO3(-) acts as the probable counteranion that exchanges for organic anions (PubMed:19129463).  May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrierr (Probable).
What are the official names of this protein?
Solute carrier organic anion transporter family member 4A1, OATP4A1, Colon organic anion transporter, Organic anion transporter polypeptide-related protein 1, OATP-RP1, OATPRP1, POAT, Organic anion-transporting polypeptide E, OATP-E, Sodium-independent organic anion transporter E, Solute carrier family 21 member 12.
What is the protein family that this protein belongs to?
Belongs to the organo anion transporter (TC 2.A.60) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BRK1B_BOMMX
Sequence: MRLWFCLSFFIVLCLEHFPETLADERNVPESEEKTEQYLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSHV
What is the function of this protein?
In vitro, produces constriction of guinea pig ileum smooth muscle.  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
Kininogen-1b.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
Protein: ABGT_ECOLI
Sequence: MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTTAILSAFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALVLGAGLAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPPMGALIFLAVGRHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAAAFNPQMHVSVIDNWYFMASSVVVLTIVGGLITDKIIEPRLGQWQGNSDEKLQTLTESQRFGLRIAGVVSLLFIAAIALMVIPQNGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPHLMIEPMKEMAGFIVMVFPLAQFVAMFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLALLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIADSSVLPLAPVSPFVPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
What is the function of this protein?
Essential for aminobenzoyl-glutamate utilization.  It catalyzes the concentration-dependent uptake of p-aminobenzoyl-glutamate (PABA-GLU) into the cell and allows accumulation of PABA-GLU to a concentration enabling AbgAB to catalyze cleavage into p-aminobenzoate and glutamate.  It seems also to increase the sensitivity to low levels of aminobenzoyl-glutamate.  May actually serve physiologically as a transporter for some other molecule, perhaps a dipeptide, and that it transports p-aminobenzoyl-glutamate as a secondary activity.  The physiological role of abgABT should be clarified.
What are the official names of this protein?
p-aminobenzoyl-glutamate transport protein, PABA-GLU transport protein.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATC_PELUB
Sequence: MTIDLKTIKHISKLSRISVDDAKANKLAGDLNSIFDFIEKLNELNTDNIEPLTSVAETTLKLRADEVKSENIRDQILKNSPEENEDFFVVPRVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RS6_STAAC
Sequence: MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWGKRRLAYEINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIREDEDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RL2_FRAAA
Sequence: MGIRRYKPTTPGRRGASVADFVEITRDHPEKSLVRPLHSKGGRNVHGRITTRHQGGGHKRAYRIIDFRRDKDGVPAKVAHIEYDPNRTARIALLHYADGEKRYIIAPVKLKQGDQVSSGVGADIKPGNALPLRNIPTGTVVHAIELRPGGGAKIARSAGASVQLVAKDGPYAQLRMPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRMRWKGRRPTVRGVAMNPVDHPHGGGEGKTSGGRHPVNPKGRPEGRTRANHKSSDALIVRRRKQNRRR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: OADG3_SALTY
Sequence: MNSSVLLGEGFTLMFLGMGFVLAFLFLLIFAIRGMSAAVNRFFPEPVPVPKAAPAAAPADDFARLKPVIAAAIHHHRRLNP
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
What are the official names of this protein?
Oxaloacetate decarboxylase gamma chain 3.
What is the protein family that this protein belongs to?
Belongs to the OadG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.