PharMolix/UniProtQA huggingface dataset:
Protein: YOHJ_ECOLU
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAVSTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPPP_SYNP6
Sequence: MTNGQEPIAMLIAVSSADRLDLWQAIVLGFVQGATEFLPISSTAHLKVVPVVLGWGDPGVAFTAVIQLGSIVAVLSYFRQDLTYVLRGLVSAVRRQDFRSEPAQMGLGILFGTIPILIGGLLIKRFIPDYDNSPLRSLAAIAIVSIVMGLLLGIAEQLSKHQRDLSQLRLADGLWMGFAQALALIPGVSRSGSTLTAGLFQGLKRDTAARFSFLLGIPAITIAGLVELKDLLEAGIDGSSLGVLAIGTLSSLIFSWLAIAWLLRFLRTHNTWSFVVYRIIFGGVILTAIATGTLQNI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRUB_ECOK1
Sequence: MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: VNP_MICAT
Sequence: MVGLSRLADGGLLLVLALLPLALDGKPAPLEKAPMAPARIIPYLRPVGKESRAALDRMVPPEDGDSRRLEGLAKEALGEGCFGNRIDRIGDVSGMGCNRRTPAPKAPLRILPYLRPIRKE
What is the function of this protein?
Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity).
What are the official names of this protein?
Natriuretic peptide, NP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: HUNKA_XENLA
Sequence: MPAAAGDGLSESPSRFLAGEKPPVHLEETFLPACISNVSRETLRNFQHTKRVGSYLIGRKLGEGSFAKVREGLHVVTGEKVAIKVIDKKKAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEEHEARKYIRQLILAVEHLHRAGVVHRDLKIENLLLDENNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKVDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKDMNPLPTHLSPAAISFLRSLLEPDPLKRPNIQQALANRWLNDNYHGKGLHTYPNRIHLEDLSQSVVLHMSEKLGYKHSDVINVILSNRACHTLAVYFLLNRKLEHYLVNMRKPDINDNVCHKNQFHQLEKYKMNKNSYEERRSKDLEKRGEPQQRPIQRKLDKCSPSHRQNACLTPQGHSNKGPVKERRSSKSERESFGGLSPFHEVRITKTGCMTSCSLEYLEMQSPDPRTPKIMRRQDSHSQETVNVNMGSRIRETHLNVVRSFESVNREDQIESLSPNHQYRVIGSPVSFSPRHSSERTLSPIFQFDNTSPSKSHFNQASFTYDDKSSPSSPESMSPTSPHSPSCNNNISGNLGSPNCVRSRGRFPMMGIGQMLRKRNQVVSPKGEKPLETRMPPLHQMSPGYASFNSSDMNGFC
What are the official names of this protein?
Hormonally up-regulated neu tumor-associated kinase homolog A, Serine/threonine-protein kinase MAK-V A, xMAK-V A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: TRMB_CORJK
Sequence: MVWMNNSENTPGSLPPGRPLQTEFNDGRDYPRLGNFSFRRGTLTDNQEALWNEHWPKLGKVLADEVIDLPEWFDRDAETIAEIGSGTGTSTAAMAPLEAEKNIVAVELYRPGLAKLLGSVVRGDIHNVRMIRGDGVEVLQRMFAPESLSGVRIYFPDPWPKARHHKRRIVQSGTLHLIASRLKPGGILHIATDHADYAEWIDELVEVEEQLEYLGWPEDQSDIPQLTDRQVITKFEGKGLDKEHIIREYLWRKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ZNF24_HUMAN
Sequence: MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWASWELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLNMGVPQIFKYGETCFPKGRFERKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAEKLLNVVKV
What is the function of this protein?
Transcription factor required for myelination of differentiated oligodendrocytes.  Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state.  In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle.  Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity).  Has transcription repressor activity in vitro.
What are the official names of this protein?
Zinc finger protein 24, Retinoic acid suppression protein A, RSG-A, Zinc finger and SCAN domain-containing protein 3, Zinc finger protein 191, Zinc finger protein KOX17.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: STHA_ECOBW
Sequence: MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQGFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTHPRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQEMSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTDSLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALVKGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMNVGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_SYNFM
Sequence: MKPSDGLEALQNLLGYRFGDEGLLHRALVHRSYLHENPHLDEKDNETLEFLGDAVLGLAISHFLLEQFPDYNEGELSRLRSAIVNERELTRIAVELNLGEYLLLGKGEEMTGGRRKASLLADSLEALLASIYLDGGLDAVLGVIKKLFDVYLRFEKREHVLKALDKDYKTQLQELTQARYKLTPVYVLDREEGPDHDKTFHMNVVLEGQVLAGGSGKSKKDAQQAAAEKALQIIAADSWSLD
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_EHRRG
Sequence: MNVYRTHLCNELREEHIDQTVTLSGWVYRKRDHGKIIFVDLRDHYGITQLVFNDSDTTIFQLITTLRLESVITIKGIVKARDSSTINETLDTGSIEVIVSSINIETASDILPINIASMQDYSEDIRLTYRFLDLRRDKVKNNIILRSKVITEIRKSMENMGFIEIQTPILTSSSPEGARDYLVPSRIHHGKFYALPQAPQLFKQLLMVSGFDKYFQIAPCFRDEDARADRSPGEFYQLDIEMSFVTQEDIFNIIEPLMINIFSKFSSKTINKEFPKISYHDAMLYYGSDKPDLRNPLVIQDVTEIFRDSEFKIFNSNIKQGMVVRAIPAPNTAHNPRSFFDSKIEFAKTLGAQGLGYITFIDDSLAKGPIAKFLDKDRLDNIKLICNIKAGDSVFFVSEIADKAALFAGEVRTLLGKELNLIEENTFKFCWVIDFPYFKYDHKEKSINFFHNPFSMPQGGLEALENQDPLNILAYQYDIVCNGIEISSGAIRNHKLNIMYKAFSIAGYTKEMVDEKFKALTRAFKFGAPPHGGIAPGIDRIVMLLADVPNIREVICFPLNQSGEDLLMGSPSEIDNDHLKLLSLNIIKKT
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASZ_BRUA1
Sequence: MGSAEKRNYVEIEGLAVAPELVEFLAKEAAPGTGVEPEKFWKGFAAIIRDLTPKNRALLAKRDELQARIDAWYKENRDKGYSQADYQQFLKDIGYLLPEGGAFSVSTTNVDPEITHIAGPQLVVPVMNARYALNAANARWGSLYDALYGTDAISEADGAEKGKGYNPKRGEKVIAWAKNFLDESAPLSTGKWADVAGLAVNDGKLEIRLTDGSATTLKDESQFKGYNGDAASPTNVLLAKHNMHVDIVINADHPIGKTDPAHIADVVLESAISTIQDCEDSIAVVDAEDKVAVYRNWLGLMNGKLEDTFEKNGKQMTRRLNGDRTYTAPDGSTLTLKGRSLMLVRNVGHLMTNPAILDAEGNEVPEGIMDAAFTSLIALHDIGPNGRHMNSREGSVYIVKPKMHGPEEVAFANEIFTRTEEMLGMKPNTLKIGIMDEERRTTVNLKEAIRAAKDRVVFINTGFLDRTGDEIHTSMEAGPMIRKGDMKQAAWIGAYEQWNVDIGLECGLSGHAQIGKGMWAMPDMMAAMLEQKIAHPKAGANTAWVPSPTAATLHATHYHKIDVAAVQEKLKSRPRAKLDDILSVPVAVRPNWTPDDIQHEIDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISAQHIANWLYHGVVSEAQVMETMKRMAAIVDKQNEGDPLYRPMAADFDKSIAFQAACDLVFKGREQPNGYTEPVLHRRRLELKQAS
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEG6_VZVD
Sequence: MDTTGASESSQPIRVNLKPDPLASFTQVIPPLALETTWTCPANSHAPTPSPLYGVKRLCALRATCGRADDLHAFLIGLGRRDKPSESPMYVDLQPFCSLLNSQRLLPEMANYNTLCDAPFSAATQQMMLESGQLGVHLAAIGYHCHCKSPFSAECWTGASEAYDHVVCGGKARAAVGGL
What are the official names of this protein?
Tegument protein UL55 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL55 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus matrix.
Protein: FADA4_MYCTO
Sequence: MIVAGARTPIGKLMGSLKDFSASELGAIAIKGALEKANVPASLVEYVIMGQVLTAGAGQMPARQAAVAAGIGWDVPALTINKMCLSGIDAIALADQLIRAREFDVVVAGGQESMTKAPHLLMNSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDMFTRSEQDEYAAASHQKAAAAWKDGVFADEVIPVNIPQRTGDPLQFTEDEGIRANTTAAALAGLKPAFRGDGTITAGSASQISDGAAAVVVMNQEKAQELGLTWLAEIGAHGVVAGPDSTLQSQPANAINKALDREGISVDQLDVVEINEAFAAVALASIRELGLNPQIVNVNGGAIAVGHPLGMSGTRITLHAALQLARRGSGVGVAALCGAGGQGDALILRAG
What are the official names of this protein?
Probable acetyl-CoA acetyltransferase, Acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: YIDD_ACET2
Sequence: MFRRWVIYIIRLYQRWISPLKTMPSCRFYPTCSQYAIDAVGRYGVIKGGFMALKRILKCHPFHPGGYDPVK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CAS3_THET8
Sequence: MSVEEAALALWAKSGNPFHPLLAHMLDTAAVALAVLRMEPPRTRALYAEDWGLPEEGALAWAAALVGLHDLGKASPVFQAGWEEGKERVQRAGLPFGELLDWVAHGVFTELFLRRLLKEKGLPERAANDLAAALGAHHGFPANAEEKSRARRHLRTEDPLWKEARRWLLEEVFRRLGAPLPPSQGNGEARPEAVLRVMALASFADWVASDPSLFPYGRDPRRGDYLKEALRLAQEALNRLGWPAFAKAQRREFGELFPYIPKPNALQESVPALLEGACTPVLLLVEAPMGMGKTEAALYAHHLLQAGLGHRGLYVALPTQATANGLFPRVRGFLERLGEGSRLELQLQHGTALLNPHYAGLLERAAPRQVGEEEEGGAVASAWFSARKRAMLAPYGVGTLDQALLGVLRVKHHFVRLWGLMNRVVVLDEVHAYDVYTSGLLQALLRWLRALGSSAVVMTATLPPSRRRALLEAWAGEEVEGQDLGPYPRVVLVGEGVKARSLPPAREVEVALEVLREVDVEPLAQRLKGALPGAVGAIVNTVDRAQDLYRALGEGTPLTLEELARRLGGISGGQAWEEVRQALPERGGEVVGKVLTDGTLVFLLHARFPAEERALRGSVVLALFGKGGPRPPRAILVATQVAEQSLDLDFDLLYTDLAPIDLLFQRSGRLHRHERPRPEEHARPRLLLGVPEDLDFGKPLYWDKVYEDYVLLATWRALSGRDRLRVPGDLEALLEEIYEGENPESFPEGLRERAKKSLKALQERRDREANTARRLSLSELDRLLAYWDEGALVAQERLEDDEEKAETQRLLTRLGDPSVAVVPLFRVGEGLFLDREGRRRAPLKGEVSREEAEALFRRAVRLSRFPLPQELLKEEPPPAWRKSGLLRGLRPLEVGRVFRSGERAFQVELDPELGVVYLPV
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity.  The N-terminal domain (residues 6-260) acts as a ssDNA endonuclease, has no activity on dsDNA.
What are the official names of this protein?
CRISPR-associated endonuclease/helicase Cas3, CRISPR-associated ssDNA endonuclease/helicase Cas3.
What is the protein family that this protein belongs to?
In the central section; belongs to the CRISPR-associated helicase Cas3 family.
Protein: TAGL_RAT
Sequence: MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVMQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPEGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVTKTDMFQTVDLFEGKDMAAVQRTVMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTDSQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
What is the function of this protein?
Actin cross-linking/gelling protein.
What are the official names of this protein?
Transgelin, Smooth muscle protein 22-alpha, SM22-alpha.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y560_NITSB
Sequence: MAGHNKWSKVKHIKAKEDAKKGKVFTKAVRDIMTAVRDGGPNPDTNAALRLAIERAKAVSMPQDNIKRAIDKASGNLPGVKYEEITYEGYGPGGVAIMVECLTDNKNRTVASVRHAFSKSGGSLGTSGSVSWMFEKKGVITVERDENEDAIMEAALESGANDILEFDEVLVIETDPADFNQVLEAVEKAGAKILESSVGLVATNEIDVDDATAEKVERLIDMLEENDDVQNVYHNMK
What are the official names of this protein?
Probable transcriptional regulatory protein NIS_0560.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SVIL_HUMAN
Sequence: MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEEETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKYGLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAGESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFTEVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSLINWPSRVKVREKLVKEESARNSPELASESVTQRRHQPAPVHYVSFQSEHSAFDRVPSKAAGSTRQPIRGYVQPADTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGRDSPVLHVCESKAEEEEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNEDFGKPAVSTVTLEHQKELENVAQPPQAPHQPTERTGRSEMVLYIQSEPVSQDAKPTGHNREASKKRKVRTRSLSDFTGPPQLQALKYKDPASRRELELPSSKTEGPYGEISMLDTKVSVAQLRSAFLASANACRRPELKSRVERSAEGPGLPTGVERERGSRKPRRYFSPGESRKTSERFRTQPITSAERKESDRCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEVVIAATEPIPASCSGGTHPVMARLPSPTVARSAVQPARLQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRMNARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASATDYKFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSFEEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQGNLDLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSSEQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRLSRRQEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAANDSTQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLKLDRLETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEMDEDFDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFMESKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF
What is the function of this protein?
May be involved in modulation of focal adhesions.  Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6.  Plays a role in cytokinesis through KIF14 interaction (By similarity).
What are the official names of this protein?
Supervillin, Archvillin, p205/p250.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, invadopodium. Cell projection, podosome. Midbody. Cleavage furrow. Note=Tightly associated with both actin filaments and plasma membranes.
Protein: GCST_FRATF
Sequence: MLKTPLYESHIAANAKMIDFSGWSMPINYGSQIQEHNNVREDCGIFDVSHMLAVDIQGSEAEKFLRYLLANDVAKLQENKAQYGCMLNHDAGIVDDLITYKVTDEHFRIVVNAGNRESDVAWFNQNAQNFDVAITPQTDLAIVAVQGPKAVAVIKRVVTKEIAAEIEALLPFSFKFFSKWMVARTGYTGEDGFEVILPATQVKKFWDSLLENGAQPAGLGARDTLRLEAGMHLYGADMDTSTTPLERGLGWSVDLSDEHRDFIGKKAYLAKKAQGVDTKWVGVVLKTKGVLRAGQEIDFDNGEKGYITSGSFSPTLKVAIGLAYVPKQADNPVVNIRGKELEVELVKPKFVKNGKSLI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: HM30_CAEEL
Sequence: MSLLDPRQFLLPAFYLDPTTQALLAQAASTSPCNKISSSSSFRISDILEQSPNNSSHSNDHDPSPQSIKSDFSTSPRASSPGGDRMGSPGSCKKSRKARTIFTDKQLQELENTFEKQKYLSVQDRMDLAHRMGLTDTQVKTWYQNRRTKWKRQATSGMDLLSEPGNLSAVQNLIRSSPYWANYITALPMGTQLPMMGLPMSMIVPPAHAFQPSSSSNSPSTHISSESPQLDVSSNSE
What is the function of this protein?
Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination.  In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway.
What are the official names of this protein?
Homeobox protein ceh-30.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATB_ECOK1
Sequence: MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTSLTPELKASMDELRQAAESMKRSYVANDPEKASDEAHTIHNPVVKDNETAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKTAAPSPSSSDKP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: INSA3_ECOLI
Sequence: MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTYTASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHLKNSGRSR
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element IS1 3 protein InsA, IS1c.
What is the protein family that this protein belongs to?
Belongs to the IS1 elements InsA family.
Protein: ARGB_ACIB3
Sequence: MPQDQHLGVDKAKILIEALPYIQRFSGKTLVVKYGGNAMTDPELESSFARDIVLLKTVGLNPIVVHGGGPQVDSFLKQLGRESDRIDGMRVTDEATMEVVEMVLGGSVNKSIVNLINKHGGRAIGLTGQDGNLLRARKLLMEKQEEDGSIKHIDLGMVGEVTGVKTDVLEMFTQSDFIPVIAPLGVDEKGNTYNINADLVAGKVAEALGAEKLILLTNISGVLDENKNLLTGLTTQEVDRLIETGVIYGGMIPKVGCALDAVKGGVVSAHIVDGRVPHATLLEIFTDHGVGTLISNRTQTTH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSTF1_XENLA
Sequence: MSKPPPKPVKPGQVKVFRALYTFEPRTPDELYFEEGDILYIADMSDTNWWKGTCKGKTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLENRVGVNGLDKAGSTALYWGCHGGHKDVVDMLLAQPNIELNQQNKLGDTALHAAAWKGYADIVELLLVKGARTDLRNNEKKLALDMATNAQCASLLKKKQAQGIVRTSSNADEYLDDEDSD
What is the function of this protein?
Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
What are the official names of this protein?
Osteoclast-stimulating factor 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR3_PIG
Sequence: MGTAKVTTPLVFAITIATIGSFQFGYNTGVINAPEAIIKDFLNNTLREKSKSMPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAITGGCLMGFCKISRSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLKLILGTELLWPLLLGFTIIPAVLQCAALPFCPESPRFLLINRKEEERAKEILQRLWGTQDVAQDIQEMKDESLRMAQEKKVTVLELFRAPNYRQPIIISIMLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHLIGLGGMAFCSLLMTISLLLKDNHTWMSFICIGAILVFVAFFEIGPGPIPWFIVAELFGQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAFYLGAYVFIVFTCFLVVFWVFTFFKVPETRGRTFEEITRAFEVQVPAGSRAEKGPIVEMSSIPPSKDAV
What is the function of this protein?
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane.  Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate.  Does not mediate fructose transport.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 3, Glucose transporter type 3, brain, GLUT-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Localized to densely spaced patches along neuronal processes.
Protein: CO4_BOVIN
Sequence: NVNFQKAIHEKLGQYTSPVAKRCCQDGLTRLPMARTCEQRAARVQQPACREPFLSCCQFAESLRKKARTRGQVGLARVGFSVVPIAAAAVSLKVVARGSFDFPVGDAISKILQVEREGALHREEMVYELNPLDPLGRTLEIPGNSDPNIIPEGDFKSFVRVTASDPLEALGSEGALSPGGLASLLRLPQGCAEQTMTLLAPTLAASRYLDKTEQWSMLPPETKDRAVDLIQKGYTRIQEFRKRDGSYGAWLHRDSSTWLTAFVLKILSLAQDQVXGSAEKLQETATWLLSQQRDDGPFHDPCPVIHREMQGGLVGSDETVALTAFVVIALHHGLAVLPDKNSRVENSISRANTFLGAKATSGLLGSHASAITAYALSLTEAPEDLRRVAHNNLMAMAKDIGDKLYWGSVTTSPSNVLSPTPAPRSPADPIPQAPAMSIETTAYGLLHLLLWEGKAELADQAASWLTRQGSFQGGFRSTQDTVVALDALSAYWIASYTAEEKGLNVTLSSLGRSGLKSHVLQLTNHQVHRLEEELQFSLGSKINVEVRGNSKGTLKVLRSYNVMDMTNTTCQDLQIEVTVMGHVEYTMEAEEDYEDYEYEDLLAGDDPEAHSRXVTPLQLFDGRRNRRRREAPKAAEERESRVQYTVCIWRTGKVGLSGMAIADITLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFGAVQEVPVGLVQPASAILYDYYNPEHKCSVFYGAPRKSKLLSTLCSADVCQCAEGKCPRQRRALERGQQDLEGYRMKFACYSPRVDYGFQVKVLREDSRAAFRLFETRITQVLHFTKDAGATADQTRNFLVRASCRLQLEPGKEYLIMGLDGATYDLKGDPQYLLDSNSWIEEMPSERMCQSTRHRTPCAQLNSFLQEYGTQXCQV
What is the function of this protein?
Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process.  It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
What are the official names of this protein?
Complement C4.
What are the subcellular locations of this protein?
Secreted. Synapse. Cell projection, axon. Cell projection, dendrite.