PharMolix/UniProtQA huggingface dataset:
Protein: DOK5_MOUSE
Sequence: MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVTELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDISLGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKKSERAASLSTVVPLPRSAYWQHITRQHSTGQLYHLQDVTSPLKLHRTETFPTYRSEH
What is the function of this protein?
DOK proteins are enzymatically inert adaptor or scaffolding proteins.  They provide a docking platform for the assembly of multimolecular signaling complexes.  DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway.  Putative link with downstream effectors of RET in neuronal differentiation.
What are the official names of this protein?
Docking protein 5, Downstream of tyrosine kinase 5.
What is the protein family that this protein belongs to?
Belongs to the DOK family. Type B subfamily.
Protein: SSRP_LISIN
Sequence: MPKGDGKLVAQNKKARHDYAIEETFEAGIVLQGTEIKSVRNARVNLKDSYARIDKGEIFLHNMHISPYEQGNRYNHDPLRTRKLLLHKKQISRLIGETKESGYSIVPLKMYIKDGYAKVLIGVARGKKKYDKRQDLKQKEAKRDIERAFKERQQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PPAC_STRZP
Sequence: MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPNEETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRVANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTTHPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRVAQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKVEAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U518_DROER
Sequence: MWLRQSSGGGVASAGHGGPLRQRPIDAATDCDPRACYDSFCKHWQQAFEIIQHSAPPSHDDVLGVVSHLDYMVTLLLVELHHCNKVSLPAAEASGPPAAPCLEFLLSENLLDKLYEWACTTGRYANAVRLEQLKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFPPDLEKRLVILLNQLCVVLMQNVHLLDLFFFSAQTQVQEQILNGNVAPPKSGTTTNFIIFSLLIPYVHREGSLGHQARDALLLCMALSQKNSNIGTYIAQYSSICPLLVTGLGGLYSRLPNSIEISSIDWHRITPDDVTEIPELTLFMNALEFCNAVVQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTLKGKHFQTNIDSQISAMSYLDLILRSITEPGLLRAFVRFLLDTEKFDGERILDALVERLNSPDANLCMVTMALFDTLLGLHCEDLMLELLLKFMLPGKHVPISHRHKINKIDPYLNSSEFFLDLSPDVMKRARDLARPKSVHEPVVSDLTPLPSLPSPVMSKTIGANWNYYGVHTGDSLYANIQAYLFEAHWRIAQCQRDCLKWANSYRYQKWPRHGQGRVHAHALELARQFFSEFGGGPIAANETGEKQLDSLQSIGESSGYESFKWRPADEESEATDTTLATTASEADLDHNSSSLSSVLGASGKREAWRTSNNNRNELILTDLDFSEDLFAQGTVSLGPFLNAIWGKLQTFTSNSLYVNLHLTGLITRLAWYPLPLIHSLLLRSDIAITSDTPSFHQVLRILKQQIDAELPVTEDSLEIIDVARSSLIDREFRLANARKGNEGSPMHHSQQQQMVTNSYATLSAATPVQATPTSAYDPFKRSDKKRRSISKSITSMFSRKSASTSTTPPNGSSASSGLSQIYAFFTGAASNLVGNNASNDGRGISQAQTSAGTCETSLSTQPQAGASRTGATATSAAASGSNSSIAGSTLTLSAQSNTTTHSASTLHGLDGGPSTGGFNSEPASLDSVASMGIIASTSGTERSRDLALCAVLMDEWLKELAAIAQEQSVVLVTEQGSL
What are the official names of this protein?
FHIP family protein GG24907.
What is the protein family that this protein belongs to?
Belongs to the FHIP family.
Protein: KAD_PSET1
Sequence: MRIILLGAPGAGKGTQAQYLMDKYGIPQISTGDMLRAAIKEGTPLGLEAKKVMDAGQLISDDIIIGLVKERITKADCENGFLLDGFPRTIPQADAMKENGVVVDHVIEFDVADEVIVERMGGRRVHPGSGRVYHVVYNPPKVADKDNETGEELIIRADDTEETVRKRLGIYHEQTMPLVDYYQAEAAAGNTQYHKLDGTQAVDAISKQLGELLG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_PSE14
Sequence: MSQTNSHGEAAGTAKPIGLLIAAVGVVYGDIGTSPLYTLKEVFQGGYGVEVTHDAILGVLSLIFWSLIWVVSFKYMAFVLRADNQGEGGIMALMALARRASAKHPKLQMMMVVFGLFGAALFYGDSMITPAVSVLSAMEGLELAFDGLDHWIVPMALIVLVGLFLIQRHGTARIGVLFGPVMVTWFLVLGALGVYGIMQSPEVLKAVNPAWGVNFFIIHPGIGVAILGAVVLALTGAEALYADMGHFGRKPISRAWFILVLPALLLNYFGQGALVLGNPETVRNPFYLLAPGWALLPLIGLSTMATIIASQAVISGAFSMTLQAIQLGYIPRMHIQHTSSDAQGQIYIGAVNWALMAGVILLVIGFESSGALASAYGVAVTGTMLCTTILVSTVMLMLWKWPPLLAVPLLICLLLVDGLFFAANVPKIFQGGAFPVLAGAVLFILMTTWKRGKQLLAERIDEGGLPLPIFISSIRVQPPHRVQGTAVFLTARSDAVPHALLHNMLHNQVLHEQVVLLTVVYEDSPRVPAAQRVEVESYGEGFYRVILHFGFIDEPDVPAALALCDLPELDFSPMRTTYFLSRETVIPSKMDGMARWREALFAFMLKNANGNLRFFKLPFNRVIELGTQVEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OAR_MYXXA
Sequence: MHLNRVLRETGVVVAAGLLYGSAAFAQSSTIIGTVIDAQSRQPAADVVVTATSPNLQGEQTVVTDAQGNYRIPQLPPGDYTLRFEKEQFKPYARSAIQLRLNRTIRVNVELLPEALGEVVEIVGAPPTIDVGSTTMGVNVDQEFIKRIAVARPGGKGGATRSFESLAELAPGAQNDNYGVSINGSTSPENGYVVDGLSTNDPAFGVNASPLSIEFVQDVNIITGGYMPEFGRSTGGVINAVTRSGSNEFHGSVFANWTPGTLEGTRKQIREEGTVITGQNQLQNLGDFGATLGGPILKDKLWFFAGFAPSFTRYQHTRTLNALRVDDEGNTIKDETDFTVADAIPGSARKYYADSRTIQYMGKLTYLINQDHNVSFALNGTPTSTGGLGKLSVNPQSGGLPGVLATRPGDFGLTETKANTTSLALKYAGAFADKKVLVDANLGWFHQTASTLPGDGSNLGDRTGLAGYSRMVYTTPRALTLFEALPEGQEGACGSTPEEQLVRSPVTGYGVGGPGFMSDQTLDRYQANAKATYLLNALGTHVFKAGVDVELLSFDQVKAYGGGVFFQEGSNYGVAGQGPAVHDARRYGYQTGPDSAVTQFTQVAKTTSTTVGGFLQDSWSIANRVTLNLGVRYDVQALYGGNGDLSLLLGNQWSPRIGAIVDPFANGRAKVFVNFARYYEQVPLNLMDRAFPGENRISARRSLAEPGQGTATSCDPSSFESQQATCNTDSNLLAIPESSRNVNRFYTGGTVGGTPVDPDIKAQSSDEIVVGAEYEVLANTRLGASYTHKDMNSVIEDMSRDDGNTYFLGNPGSGFAGEFPTPVRNYDNVTVYLNRTFADGWLAQANYTWSRLYGNYPGLFRPETGQLDPNILSDFDLIELLENRTGLLPFDRTHQIKVFGAKEFNISNALSASVGVSYRGSSGTPINYWGSHWAYLQDESFVLPRGAGGRTPWINTIDSNIGVNYRVSKDSVVSFTLDVFNLFNFQGVNTVDQTYTLRDIKPIPGGTPADLENLPGRVEFQDQAPRDEPFGSVDGDVNKNFKNPLSYQAPRQVRFGIRYTF
What is the function of this protein?
Required for cellular adhesion during fruiting body formation.
What are the official names of this protein?
Protein oar.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: OPR1_NEIMC
Sequence: IQPPKTFSSLLFSSLLFSSAAQAASEDGSRSPYYVQADLAYAAERITHNYPEPTGADKDKISTVSDYFRNIRAHSIHPRVSVGYDFGGWRIAADYASYRKWKESNFSTKKVTEEIKDNYKETKTEHQGNGSFHATSSLGLSAIYDFKLNDKFKPYIGARVAYGHVKHQVHSVETKTTTVTSKPKGGTPAGGPVIKTDPSKPPYHESHSISSLGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEASLGMRYRF
What are the official names of this protein?
Opacity-related protein POPM1.
What is the protein family that this protein belongs to?
Belongs to the opacity porin family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: G6PI_LACJO
Sequence: MSKVVHFDASKLTPFVHENELKEMQAMVTAADQELREGTGAGSDFRGWIDLPINYDKDEFDRIKKAAKKIQNDSEVLVGIGIGGSYLGAQASIEFLNSSFYGREKEKYPTVVFCGNSLSGSYLYDLLEWLGDKDFSINIISKSGTTTEPSIAFRVLKDKLIKKYGKEEAAKRIYATTDRAKGALKTEADAEGYEEFVVPDDIGGRFSVLSAVGLLPIAVAGGDIDAMMKGAADARAAYTDPDVLKDSPYQYAAMRNILYRKGYTTELLENYEPSLRMFGEWWKQLMGESEGKDQKGIYPSSANFTTDLHSLGQYIQEGRRNLMETVIRVEHPTHDVTIPDDKENLDQLNFLSGKTMNYVNDRAYEGVVLAHTDGGVPVMTVDIENQTAHTLGYLIYWFELAVGISGYLNGINPFNQPGVESYKRNMFGLLNKPGYEDLHDDLTKRLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIA1_GIAIN
Sequence: MPKVTDIANELKQAIDAKDEVQIAFIASEYSAESREKIAKAYVASYGKELPDDIKKALKGGSEESLLMDLFSDRHEVRAQHIRDALSGRNDHMAFFDTVILCTPEDWHETVAAYTRMFKKPLVEDFMKDVGRKEDWCLLMEKWMAHERVSRPGSPEDEAQRLDQAFDQKNTAYLIDFFGTVPSAEYRPIAEAFKAQNGKSIEQAIATIYTKTDYYTFYCAHFALLGMHRLAAYLINCACNDKGDEKRMRRITGMMVDKCLGAKHAYKIYGDMGTDIERCFDKRMAPILRTLWRVK
What is the function of this protein?
Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst.  They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.
What are the official names of this protein?
Giardin subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the annexin family. Giardin subunit alpha subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Most likely in the edges of the ventral disk microribbons.
Protein: PRS39_MOUSE
Sequence: MWGSRAQQSGPDRGGACLLAAFLLCFSLLHAQDYTPSQTPPPTSNTSLKPRGRVQKELCGKTKFQGKIYGGQIAKAERWPWQASLIFRGRHICGAVLIDKTWLLSAAHCFQRSLTPSDYRILLGYNQLSNPSNYSRQMTVNKVILHEDYSKLSRLEKNIVLIQLHHPVIYSTHIFPACVPDGTTKVSPNNLCWISGWGMLSADKFLQAPFPLLDAEVSLIDEEECTTFFQTPEVSITEYDVIKDDVLCAGDLTNQKSSCRGDSGGPLVCFLNSFWYVVGLANWNGACLEPIHSPNIFTKVSYFSDWIKQKKANTPAADVSSAPLEEMASSLRGWGNYSAGITLKPRISTTLLSSQALLLQSIWLRIL
What is the function of this protein?
May play an important role in the sperm/egg interaction; released during the acrosome reaction.
What are the official names of this protein?
Inactive serine protease 39, Inactive testicular serine protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted.
Protein: PGK_CHLFF
Sequence: MDRLTVRDLSPEEKKVLVRVDFNVPIKDGKILDDIRIRSAMPTINYLLQKRAAVILMSHLGRPRGSGFEEKYSLQPVVEVLEGYLGHHVPLAPDCIGEVARQAVAQLSPGRVLILENLRFHRGEEHPEEDPAFAAELSSYGDFYVNDAFGTSHRKHTSVYTVPQAFPGRCAAGLLMEKELEFLGTHLLISPKRPFTAILGGAKVSSKIGVIEALLSQVDNLLLAGGMGYTFLKALGKSVGNSLVEESGIELATRVLQIAKQRNVRIVLPVDAKVAKTCDSGVSWSEVSINQGIPADLEGLDIGTQTIQEFCKIIDASATVFWNGPVGVYEVPPFDQGSMAIANCLARHPSATTVVGGGDAAAVIALAGCSSQVSHVSTGGGASLEFLEKGFLPGTEVLSPTRG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBCV_ECOLI
Sequence: MAQVAIFKEIFDQVRKDLNCELFYSELKRHNVSHYIYYLATDNIHIVLENDNTVLIKGLKKVVNVKFSRNTHLIETSYDRLKSREITFQQYRENLAKAGVFRWITNIHEHKRYYYTFDNSLLFTESIQNTTQIFPR
What are the official names of this protein?
Uncharacterized protein YbcV.
What is the protein family that this protein belongs to?
To E.coli YcgX and YdfO.
Protein: RSMH_BACSU
Sequence: MFQHKTVLLRETVDGLNIKPDGTYVDCTLGGAGHSTYLLQQLSEKGRLIAFDQDDTALQHAKEVLSDYKGQLILIKSNFRYLKEYLNEQGVTEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQSATLSAKEVVNEWRYEDLVRIFFKYGEEKFSKQIARKIEEARMKSPIQTTGQLVDLIKDAIPAPARRSGGHPAKRVFQAIRIAVNDELRVFEEALEQAIEVLKPGGRVSVITFHSLEDRICKTTFKEKSSLPELPPGLPVIPEEFEPELKLITRKPITASQEELEENNRARSAKLRIAEKRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC178_HUMAN
Sequence: MTENKTVSSSSTRDDQTNIGLTCQEVKALREKAWSRTNEGNAMSQSLVLYGASKENSEGFHESKMTNTEGVNKGIYFSYPCRRHSCAVVNIPAPCVNKMISHIQDVESKIQEHLKRFETSFEEWSRTSSTKDLKEDWSVTTPVKEVKPGEKRDEKCPELKQEMETLLSEAIRLIKSLETDRADAEEALKQQRSRKNMINMKIDSWSVWKLQELPLAVQKEHEAYLSDVIELQWHLEDKANQLQHFEKQKTELEEANAKIQADIDYMNEHGPLLDSKQNQELQDLKNHYKKKMEVMDLHRKVNEELEEALEACENARLKAQQIKEEIDKDIYQDEKTIEAYKREIYQLNSLFDHYSSSVINVNTNIEEKEEEVTEAIRETKSSKNELHSLSKMLEDLRRVYDQLTWKQKSHENQYLEAVNDFYAAKKTWDIELSDVAKDFSAISLACTKLTEDNKKLEIDINKITVKTNESIRKKSKYESEIKYLTIMKLKNDKHLKNIYKEAYRIGTLFHLTKHKTDEMEDKIAEVRRKFKGREEFLKKLTQGEVAAGMVLQKKLYSIYEVQALERKELIKNRAICAMSLAELQEPLLQLEDEAERIRSLDKEHSVMLNNIIDQKDLIRRKVGKVKKKLRKKGKKTLDALIETESKRSAIFKDLEATKSKTMIFYAKINELNEELKAKEEEKKSFDQTLEILKNKFITMRFKREHAQTVFDHYMQEKKDCEERIFEEDQRFRVLLAVRQKTLQDTQKIIADSLEENLRLAQEYQQLQITFLKEKDNYFNIYDKQLSLDTSIRDKKQLCQLQRRMHTLWQEHFKLVVLFSQMRLANFQTDSQESIQKILAVQEESSNLMQHILGFFQTLTDGTCENDG
What are the official names of this protein?
Coiled-coil domain-containing protein 178.
Protein: YDGB_BACSU
Sequence: MPSTVINLYYLKINSISGNGSITIGEAAYNSPTNNQKSQGTNSSFGDTSPTESVMENFLNDPDVNDQTSIGNSDTSNVNAPPIAPPPILD
What are the official names of this protein?
Uncharacterized protein YdgB.
Protein: Y1070_FRAP2
Sequence: MSREQQLIDLLYKEVVPAEGCTEPVALAYCAAKTRDVLGHIPDRIDVFASGNMIKNVKSVTVPNSGGMIGIEASVAMGTIAGNAAKELMVISGVTKADLPKVQEYLQKDCIKVFNASKPIKLYIRIEAYYKQDKVIVEFKYTHTNITLIKKNDEIIYEVDDADNKSNLVDEIISKFSIKEIYKIASHLDTSKISDMLDKIVKDNSNISNEGLVHQYGIQTGRNIRSGIDNGFYGDDIRNRAAAAASAGSDARMGGSALPVMTAAGSGNIGLTLSLPLIEFAKSKGKSQEELYRALFFAIVSTVYIKSSIGRLSALCGPTCASAGIAGGLAMMLDLSEDKVEKSIINALAGIIGIMCDGANSSCSIKIANSVYAAFDAVNAAMLGNTVTPHDGIVGDDVEGTIKNIAILATGKGMNETDDAILGVMTGRLADICK
What are the official names of this protein?
UPF0597 protein Fphi_1065.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: EFTU_MANSQ
Sequence: KNMITGAAQMDGAILVVSGADGPMPQTKEHILLAKQVGVPNIVVFLNKEDQVDDDELLELVELEVRDTLSSYEFPGDDIPVVPGSALLALEALTEKPAMSAGENKWVDKIFALMDAVDSYIPTPERDTAKTFLMAIEDVFSITGRGTVATGRVERGTVNCGDVVEIVGLGDTREVTVTGLEMFQKHLDESVAGDKVGVLLRGIQKDDIERGMVLAKKGTITPHTKFESQVYVLSK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IF2_PSEP1
Sequence: MTQVTVKELAQEVEAPVERLLQQMREAGLPHTDAGQVVTDNEKQTLLTHLKSSHKSKAEEPRKITLQRKTTSTLRVAGSKSISVEVRKKKVFVQRSPEEIQAEQKRELEERRAAENAARDKVEAEVRQRNEEQARRQAAGSTAAAPAPAAKPEPAPAAAPVAAPAPVVADAPASEDAAARAAERKKDETRRNESRTRDDDRRRGEAPRVSIKVKVKEKEKAPTPRAAPRTTDEESDGARRGRGGKSKLKKRNQHGFQNPTGPVIRDVTIGETITVSELANQMSVKGAEVVKFMFKMGTPVTINQVLDQETAQLIAEELGHKVTLVSDTALEDSLAESLKFEGQTESRAPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETDRGMVTFLDTPGHAAFTQMRARGAKATDIVILVVAADDGVMPQTREAVQHAKAAGVPLVVAVNKIDKPGADLDRIRNELSVEGVTSEDWGGDTPFVKVSAKMGTGVDELLEAVLLQAEILELTATPTAPGRGVVVESRLDKGRGPVATILVQDGTLRQGDMVLCGSNYGRVRAMLDENGKPVKEAGPSIPVEILGLDGTPEAGDELSVVADEKKAREVALFRQGKYREVKLARAHAGKLENIFETMGQEEKKTLNIVLKTDVRGSLEALQGSLGGLGNDEVQVRVIGGGVGGITESDANLALASNAVLFGFNVRADAGARKIVEQEGLDMRYYNVIYDIIEDVKKALTGMLGSDVRENILGVAEVRDVFRSPKFGAIAGCMVIEGTVYRNRPIRVLRDDVVIFEGELESLRRFKDDASEVRSGMECGIGVKSYNDVKVGDKIEVFEKVQVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOSA_ECO27
Sequence: MALRNKAFHQLRQLFQQHTARWQHELPDLTKPQYAVMRAIADKPGIEQVALIEAAVSTKATLAEMLARMENRGLVRREHDAADKRRRFVWLTAEGEKVLAAAIPIGDSVDEEFLGRLSAEEQELFMQLVRKMMNT
What is the function of this protein?
Involved in the temperature-dependent positive control of flagellum-driven swimming motility and cellular aggregation.  Regulates fliC expression by directly interacting with fliC promoter.
What are the official names of this protein?
Transcriptional regulator HosA.
Protein: ASL1_BACSE
Sequence: NYIYSGHNYHQ
What is the function of this protein?
Degrades acharan sulfate and, to a lesser extent, heparin and heparan sulfate.
What are the official names of this protein?
Acharan sulfate lyase 1.
Protein: PTH_RHOP5
Sequence: MRLLVGLGNPGAKYQGNRHNIGFMALDEIARRHGFSPWRRRFQGETADGSIGGERVTLLKPLTFMNDSGRAVQDAASFFKLGLPEIIVLHDEIELPAAKLRVKVGGGIAGHNGLRSISAHIGNEYRRVRIGVGHPGVKELVHGHVLNDFAKAERPWVEAMLEAITDNADLLVGDRDSQFQNKVHLALQAKGFLDKSDNGAK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_BRAHW
Sequence: MEVILKRDFISLGYEGDICKVKDGYARNYLIPRNIAVVKNAANLRTLAQMQKSLEKKRAKRKMEAEILKGKIVDITVVIPMKVAENGKLYGSVSQQTIVDALKEKEIDINKRDVHMEKHIKELGDFEVEIKLYHSVNANIKIKVVNVDENAAAEEVKEENTAAVEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: KAD_RHIE6
Sequence: MRLILLGPPGAGKGTQAQRIVEKHGIPQLSTGDMLRAAVGVGTEVGKRAKAVMDAGKLVSDEIVIAIVSERIDQPDCANGFILDGFPRTLVQADATEAMLKAKGLDLSVVIEFRVDDQELVRRVDGRYTCAQCGTVYHDTDKVPVEEGVCDKCGSTHFKRRPDDNAETMIKRLEVYYKETSPLIGYYYAKGKLRSVDGMAEIDQVTTEVESILSKL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFAC_ECOLX
Sequence: MRDTSSGRMRTGVTGLALAVMVACVMFRAESGIARTYSFDAAMLKGGGKGVDLTLFEEGGQLPGIYPVDIILNGSRVDSQEMAFHAERDAEGRPYLKTCLTREMLARYGVRIEEYPALFRASGEGRGASVAEEACADLTAIPQATESYQFAAQQLVLGIPQVAPSAAEGDWPEALWDDGIPAFLLNWQANAGRSEYRGYGKRVTDSYWVSLQPGINIGPWRVRNLTTWNRSSGQSGKWESSYIRAERGLNGIKSRLTLGEDYTPSDIFDSVPFRGAMMSSDESMVPYNLREFAPVVRGIARTQARIEVRQNGYLIQSQTVAPGAFALTDLPVTGSGSDLQVTVLESDGTAQVFTVPFTTPAIALREGYLKYNVTAGQYRSSDDAVEHTSLGQVTAMYGLPWGLTVYGGLQGADDYQSAALGLGWSLGRLGAVSLDTTHSRGQQKGHDYETGDTWRIRYNKSFELTGTSFTAASYQYSSDGYHTLPDVLDTWRDDRYAYRHTENRSRRTTLSLSQSLGQWGYVGLNGSRDEYRDRPHRDYFGASYSTSWNNISLSVNWSRNRNSGGYYGGWSRTEDSVSMWMSVPLGRWFGGADNDISTTAQMQRSTGQDTRYEAGLNGRAFDRRLYWDVREQMVPGSESHADTSRLNLTWYGTYGELTGMYSYSSTMRQLNAGMSGSMVAHSEGVTFGQRTGDTVALIAAPGVSGASVGGWPGVRTDFRGYTLAGYASPYQENVLTLDPTTFPEDAEVPQTDSRVVPTKGAVVRAGFRTRVGGRALVSLARQDGTPLPFGAVVTVEGERGQAAGSAGVVGDRGEVYLSGLKESGKLKAQWGENSLCHADYRLPEEKGPAGIFLTRTVCM
What is the function of this protein?
Involved in the export and assembly of AFA-III afimbrial adhesin subunits across the outer membrane.
What are the official names of this protein?
Outer membrane usher protein AfaC.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: KCNE2_MOUSE
Sequence: MATLANLTQTLEDAFKKIFITYMDSWRRNTTAEEQALQARVDAENFYYVILYLMVMIGMFSFIVVAILVSTVKSKRREHSQHPYHQYIVEDWQEKYKSQILHLEDSKATIHENMGATGFTVSP
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.  Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr).  May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current.  May associate with HCN1 and HCN2 and increase potassium current (By similarity).  Interacts with KCNQ1; forms a heterooligomer complex leading to currents with an apparently instantaneous activation, a rapid deactivation process and a linear current-voltage relationship and decreases the amplitude of the outward current (By similarity).  KCNQ1-KCNE2 channel associates with Na(+)-coupled myo-inositol symporter in the apical membrane of choroid plexus epithelium and regulates the myo-inositol gradient between blood and cerebrospinal fluid with an impact on neuron excitability.
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 2, MinK-related peptide 1, Minimum potassium ion channel-related peptide 1, Potassium channel subunit beta MiRP1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with KCNB1 at the plasma membrane.
Protein: YB109_YEAST
Sequence: MSLRPCLTPSSMQYSDIYIYPNTTLTLPYFNPSNLSLNLPSHYPTSPLVTLSHSTIPLPTTIHPSTYYHQSTVHHNRYPPISHIQLHYHLPCHYSTIHHLLLTILLFYPPY
What are the official names of this protein?
Putative uncharacterized protein YBL109W.
Protein: PFD2_SCHPO
Sequence: MAEQPSRQQILQTQYNSYKSRLQQIAQKIVDLETDADEHKLVMDTLNSMDNNRRCFRMIHGVLVERTVGTVVPILKTTQEGIQTAMNGLLDQYKQLEAEFQKFQKDNKIQVVRQ
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Probable prefoldin subunit 2.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: SASA_PROM9
Sequence: MNDKKELKLILVAARNQLSSSDIKSLIAYLESDDCNFEISLQISEPTEQPELLELHRLVAIPALIKVSPAPKQIFAGSNIFSQLQKWLPRWNQEGLTKNLGINLQPSKIDSIRTQKEYLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAVQSQKLGQIDIAKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRDIEIDTDIPSDLPSVFADQRRMRQVFLNLIENAIKFSKDYGSIKITMIHKTNQWVEITICDKGAGIPLNEQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSEIGVGSCFHFTVPVWQGQNKEQHYLTKG
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.