PharMolix/UniProtQA huggingface dataset:
Protein: SCX3_TITST
Sequence: KKDGYPVEYDNCAYICWNYDNAYCDKLCKDKKADSGYCYWAHITCYCYGLPDSEPTKTNGKCKS
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Toxin Tst3, P-alpha* NaTx3.5.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_PROMH
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: HTPG_ECOHS
Sequence: MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_SYNPW
Sequence: MVATPSATTGLQVAQDYVIADINQAEFGRKELDIAETEMPGLMALREKYGTEKPLKGARIAGSLHMTIQTACLIETLVELGAEVRWASCNIFSTQDHAAAAMAARDIPVFAVKGETLEEYWEYTHRILEWGDGGSPNMILDDGGDATGLVMLGSKAEQDITVLDNPGNEEETFLFASIKKKLAQDPTFYSRTKAQIQGVTEETTTGVARLYKMQKSGELPFPAINVNDSVTKSKFDNLYGCRESLVDSIKRATDVMVAGKQALVMGYGDVGKGSAQSLRGLGATVCIAEVDPICALQAAMEGYRVVRLEDVVEDMDIFVTATGNYQVIRNEHLLKMKDEAIVCNIGHFDNEIDVASLKDYEWENIKPQVDHITLPSGNRIILLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQIELFTKGNEYGKEVYVLPKHLDEMVARLHLDRIGAKLTELSKDQADYINVPVEGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C7352_ARATH
Sequence: MMVTLVLKYVLVIVMTLILRVLYDSICCYFLTPRRIKKFMERQGITGPKPRLLTGNIIDISKMLSHSASNDCSSIHHNIVPRLLPHYVSWSKQYGKRFIMWNGTEPRLCLTETEMIKELLTKHNPVTGKSWLQQQGTKGFIGRGLLMANGEAWHHQRHMAAPAFTRDRLKGYAKHMVECTKMMAERLRKEVGEEVEIGEEMRRLTADIISRTEFGSSCDKGKELFSLLTVLQRLCAQATRHLCFPGSRFLPSKYNREIKSLKTEVERLLMEIIDSRKDSVEIGRSSSYGDDLLGLLLNQMDSNKNNLNVQMIMDECKTFFFTGHETTSLLLTWTLMLLAHNPTWQDNVRDEVRQVCGQDGVPSVEQLSSLTSLNKVINESLRLYPPATLLPRMAFEDIKLGDLIIPKGLSIWIPVLAIHHSNELWGEDANEFNPERFTTRSFASSRHFMPFAAGPRNCIGQTFAMMEAKIILAMLVSKFSFAISENYRHAPIVVLTIKPKYGVQLVLKPLDL
What is the function of this protein?
Cytokinin hydroxylase that catalyzes the biosynthesis of trans-zeatin via the isopentenyladenine riboside 5'-monophosphate (iPRMP)-dependent pathway.  Can use isopentenyladenosine-5'-monophosphate, isopentenyladenosine-5'-diphosphate and isopentenyladenosine-5'-triphosphate as substrate.
What are the official names of this protein?
Cytokinin hydroxylase, Cytochrome P450 35A2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GMHA_COXBR
Sequence: MNLFQRVKYNFEESIKTKTAAIELLVDPIVQAGELMSQCLLNEHKILSCGNGGSAADAQHFSSEMLNRFETERPSFPALALTTDASTVTAIANDYSYAEVFSKQIAGLGSTGDILLAISTSGHSKNILQAITAAHIRGMNVVALTGRDGGELFTLLGTDDIEIRVPAESTARIQETHALIIHCLCDIIDRKLIPSSEDH
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1193_STAA8
Sequence: MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKIDKDEFVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDEEIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETAIITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNILMASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLTYAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLNEMLAEDSEILTVIIGQDAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE
What are the official names of this protein?
Uncharacterized protein SAOUHSC_01193.
Protein: RTCA_CALMQ
Sequence: MITIDGSMGEGGGQILRTALALSIITGKPFRIINIRARRSNPGLQPQHLASVMAAARISNAKVDGAYKGSLSLTFEPGDVKCGDYSIDIGTAGSISLVLQTLLPVLAVVNCGEVTLDITGGTDVPKAPPIDYVRFVLAHNLSLMGVGIKVELIRRGHYPRGGGKVKVTVKPAGRLKPINITELGELKGIWGLSHAVRLPSHVAVRQAKAAEDYLSKLGLKPSISLEYYEQGKDPHLGPGSGITLWAESTNGQRIGADSLGERGKPAEDVGREAAEALAAVINAGAAFDDHMGDMLIPFLALAEGRSEYTVVNLTSHLSTNISIVKLFLNANIETMNYNKKVKVTINPITAPRKP
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_DEIGD
Sequence: MFKRVLLKLSGEFLSGPAPDGSAGFGISPDTTAQLARLITDALTGTNVELAIVIGGGNLWRGARNGKGMDAATADYIGMLGTVMNAMALQDAMEAAGQPTRVMTAIQMAAVAEPYIRRRAIRHLEKGRVVIFGGGNGAPFFTTDTTATLRALEIGADVVLMAKNKVDGVYDSDPRKNPDARRLDSLTHIEVVERRLEVMDATALTLCMDKGLPIVVFDLFQPGNLRRLLEGERVGTLIESERRPERLSHDPSSHVPR
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_MANSM
Sequence: MIGLVGRKVGMTRIFTEEGVSIPVTVIEIEANRVTQVKTLENDGYSAVQVTTGSKKASRVTKPEAGHFVKAGVEAGRGLWEFRTEGEEFTLGQEINVDIFADVKKVDVTGTSKGKGFQGGVKRWNFRTQDATHGNSLSHRVLGSIGQNQTPGRVFKGKKMAGHLGAERVTVQSLEVVRVDAERKLLLVKGAVPGATNSDVIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SIP5_SCHPO
Sequence: MGNTIGKERQENDEELIQHLVQLVDGGFLDPQGVYSSAPAYKTNIVRKLMLERRLMPFYKGLDSYSKDWPADKVVEVVEKALGPHKSALLHCAIRQSRSLSVGNTRSLKRDSRGSSDHLLTRNRSNSTPGSISADYRTTAITTIYANAMECPICFLYYPSNFNYTRCCAQPICSECFVEIRRAEPHLPTVHANEPTPNEFDLISEPAKCPYCMTERFGVIYKPNPKLTPFSFNNNPDTLPSNIAPMGTLSKSSLPLHHIPWPPNQHIKFAHDDKNVVSTDFIHPDWQYKLERARRRALRRAANATLLNSHLLETGPANANANHNTDLSHDPTSHGGPRRTLSSRRQHYLANVEQLMLAEAIRQSLLDAQSNDSTNSLPSTEVSQPDSTNISNEQEIVQPQPTHTTNVALVEEINRPDSVESAITASSSIDTGNENETQEVNSDSLPQFVHQTMTQTNFQESSPSVAADETRVHNVDEYIEQQDLDELIHSPIASTNPFLADQFARSETVDLNAHICSPALSVSDDGVTATNKTQSSFPSVYEHQLKSNELERGH
What is the function of this protein?
May negatively regulate the snf1 kinase.
What are the official names of this protein?
Protein sip5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMA1_XENLA
Sequence: MPTTNEADERMRKFKNKGKDTAELRRRRVEVSVELRKAKKDEQILKRRNVCFPEELILSPEKNAMQSIQVPQLSLEEIVQGMNSGDNENELRSTQAARKMLSKERNPPLNDIIEAGLIPKLVEFLSYHNNSTLQFEAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYRDALISCNVIPPLLTLVNPQTPLGYLRNITWTLSNLCRNKNPYPPMSAVLQILPVLTQLMLHEDKDILSDTCWAMSYLTDGSNDRIDVVVKTGLVERLIQLMYSPELSILTPSLRTVGNIVTGTDKQTQAAIDAGVLSVLPQLLRHQKPSIQKEAAWALSNIAAGPAPQIQQMITCGLLSPLVDLLKKGDFKAQKEAVWAVTNYTSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAISNIFLAAEKLGEQEKLCLLVEELGGLEKIEALQTHDNRMVYHAALALIEKYFSGEEADEMNALEPEVGNDAYTFQVPNMQKESFKF
What is the function of this protein?
It is essential for selective protein import into nucleus.  Promotes signal-dependent binding of karyophilic proteins to the nuclear envelope.
What are the official names of this protein?
Importin subunit alpha-1, Karyopherin subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_RICPU
Sequence: MLLVIGLGNPGKEYQYTRHNVGFIAIEKIANQYNSSFSTKKKFNCEIAETISDRQKIIFIKPTTYMNLSGKSVISVKTYYNIYPAKIFVIHDDIDLETGRIKFKTGGGNGGHNGLKSIDGVIGNNYNRIRIGVGRPQNNQDVADYVLNHFSKPEYKTVMQAIDRITSNFGLILENKLEEFKN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_NEIMA
Sequence: MAKVSKRLKALRSSVEANKLYAIDEAIALVKKAATAKFDESVDVSFNLGVDPRKSDQVIRGSVVLPKGTGKITRVAVFTQGANAEAAKEAGADIVGFEDLAAEIKAGNLNFDVVIASPDAMRIVGQLGTILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVQYRTDKAGIVHATIGRASFAEADLKENFDALLDAIVKAKPAAAKGQYLKKVAVSSTMGLGIRVDTSSVNN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: COX2_VANPO
Sequence: MYILTNILSIISNDVPTPYALGFQDSATPNQEGILELHDNIMFYLLVILGLVSWMLYTITKTYSKNPLPYKYMKHGQFIEIIWTIFPAVVLLIIAFPSFILLYLCDEVISPAMTVKVIGYQWYWKYEYSDFVNSNGETVEFESYIIPDDLLEEGQLRLLDTDTSVVVPVDTHIRFIVTAADVIHDFAIPSLGIKVDANPGRLNQVSALIQREGVFYGMCSELCGTGHSQMPIKIEVVSLGKYLGWLNEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL11_FLAPJ
Sequence: MAKEVSKVVKLQVKGGAANPSPPVGPALGAAGVNIMEFCKQFNARTQDKAGKVCPVQITVYKDKSFDFVVKTPPAAVQLMEAAKLKSGSGEPNRKKVASVTWDVIKAIAEDKMVDLNAFTAESAMSMIAGTARSMGITVTGDSPLKK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: FDL48_ARATH
Sequence: MKRRKRGRGIVNADRISQLPEALIIQILSLLPTEVAVTTSVLSKQWQFLWKMLPKLNFDSLDQRHEFKTFSKNVKRALLSHKAPVLHSLHLIVHLHLCNSMNTAKLIGIAFACNLRKLVLEVDGGRFSIPESLYNCETLDTLELKYSILMDVPSSICLKSLRTLHLHYVDFKDNESALNLLSGCPNLENLVVHRYPFSSVKTYTIAVSSLKRLTIYTSSTVDPRAGYVINSPSLTYLKIVGQIGFCLIENVPELVEASMIVSSQIINKNLLESLTSVKRLFLEFSPLMIKFPAGSIFYQLVYLELLTHEAECLNLLTLMLNSSPKLQILKLLSPKYQSWKKDVVGKWNKPKIVPECLLFHLETFMWKGYEWKRNDETEVAKYILSNTNRLKRATFFSKPISSEERVKMVKNLNSVVRALNSCQLLIK
What are the official names of this protein?
Putative F-box/FBD/LRR-repeat protein At4g13965.
Protein: RF1_WOLPP
Sequence: MDIENNLQDLKKKFSDVERNLENPTNLSQKEFVSFSKEYSELRPIIEIIDEYNILKEEISDLEEIMKDENSDGDIKELAKEELLEKQKIVLPKVKAKLKLALLPKDEDDSRNAILEIRAGTGGEEAALFAAMLFRMYQKYAERRNWKFEPISISNTGIGGYKEASALINGTEVFARLKFESGVHRVQRVPETESSGRLHTSAATVAILPEVEEVDFEIEEKDLRIDVYRSSGPGGQSVNTTDSAVRVTHLPTGIVVIQQDEKSQHKNKAKALKVLRARLYEIERQKKEMERSTMRKSQIGSGDRSERIRTYNFPQSRITDHRINLTSHRLEQIIKEGELDEFIEALISRNEAERLTGGGNVTF
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGHB_CHAGB
Sequence: MASFNNVLTKAAAGRLCKAMGVRMVANPLVVQLAANAGFEALFIDLEHSTLSLADASAIACAGLLSGLTPLVRVPYQCGIGFVQQALDGGAMGIVFPHIHTAADARAAVQTCKFPPLGVRSMWGQQPALGMRVTAIGRIVEVCNAAASSVIVMIEAASSIENIEAIAAVEGVDVLLVGCLDLSTDMGMPGRFETRAFRTALEKVSAACRHSGKTMGLAGIYNNRELHEWAINTLNVRFMLCQQDSNLLAMAAVDCASAVAKIDRARLLN
What is the function of this protein?
4-hydroxy-4-methyl-2-oxoglutarate aldolase; part of the gene cluster that mediates the biosynthesis of the tetramic acid Sch210972, a potential anti-HIV fungal natural product that contains a decalin core (PubMed:26360642).  The PKS module of cghG together with the enoylreductase cghC catalyze the formation of the polyketide unit which is then conjugated to 4-hydroxyl-4-methyl glutamate (HMG) by the condensation domain of the cghG NRPS module (PubMed:26360642).  One unique structural feature of Sch210972 is the tetramic acid motif proposed to be derived from the non-proteinogenic amino acid HMG, by a Dieckmann-type condensation catalyzed by the reductase domain of cghG (PubMed:26360642).  The aldolase cghB catalyzes the aldol condensation of 2 molecules of pyruvic acid to yield the intermediate 4-hydroxyl-4-methyl-2-oxoglutarate (HMOG), which can then be stereoselectively transaminated by an unidentified enzyme to form HMG (PubMed:26360642).  The Diels-Alderase cghA then uses the Dieckmann product released by cghG as substrate and catalyzes the Diels-Alder cycloaddition to form the decalin ring of Sch210972 (PubMed:26360642).  CghA also suppresses the nonenzymatic formation of the alternative stereoisomer (PubMed:26360642).
What are the official names of this protein?
4-hydroxy-4-methyl-2-oxoglutarate aldolase cghB, Sch210972 biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: CF300_XENTR
Sequence: MSAGSFSTEAAKFSFSPILNKTFGFLTNRDTRELLMKWSMNGRITAQAFRYDECFQPYQKNDFVWAFFQDPDVLSHLKIVSENSGQWVTLGTKVKKVDVQEILCSQLSMSLFDCLYSEGIVRESGHICKCLDEYLDDFTISDELRKVLLLDDCEKHDVFSQSDREQFLFLLFKHLCLGGAICQFEDTIGPYLETTKSIYKDLLSVQKDPETKQIRIISTVFKVSAYDENGMCYPSGRPHQQTFAYLIVDPLKRHVYVLYHCFGGGAF
What is the function of this protein?
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility.  May play a role in outer and inner dynein arm assembly.
What are the official names of this protein?
Cilia- and flagella-associated protein 300.
What is the protein family that this protein belongs to?
Belongs to the CFAP300 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme.
Protein: ESMC_DROME
Sequence: MSSLQMSEMSKTYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQHKRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQIQPAEKEVLPVTAPLSVHIANRDAYSVPISPISSYAGSPNSNTSSTSHSLLTTIDVTKMEDDSEDEENVWRPW
What is the function of this protein?
Transcriptional repressor of genes that require a bHLH protein for their transcription (PubMed:24618901).  May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes (PubMed:1528887).  Contributes to the neural-epidermal lineage decision during early neurogenesis (PubMed:1427040).  Part of the Notch signaling pathway, plays a role in neuroblasts proliferation in embryos and larvae (PubMed:10790334, PubMed:22357926).  In the larval brain, together with other self-renewal transcriptional repressors such as klu and dpn, required for type II neuroblast self-renewal and for maintaining erm in an inactive state in intermediate neural progenitors (INP) derived from type II neuroblasts (PubMed:24618901).
What are the official names of this protein?
Enhancer of split mgamma protein, E(spl)mgamma, Split locus enhancer protein mB.
What are the subcellular locations of this protein?
Nucleus.
Protein: IP23_CAPAN
Sequence: KACPRNCDTDIAYMVCPSSGERIIRKVCTNCCAAQKGCKLFRSNGSIKCTGT
What is the function of this protein?
Potent inhibitor of trypsin and a weaker inhibitor of chymotrypsin.  It does not inhibit elastase and subtilisin DY.
What are the official names of this protein?
Proteinase inhibitor PSI-1.2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I20 (potato type II proteinase inhibitor) family.
Protein: RS2_WOLPM
Sequence: MTNLPKVTVRDLAESGVHFGHKISRWNAKMAPYIYGVHQENRIHIIDLRKTLPLLQVAMKALYDVAFQGGRILFVGTKFQAFDIIASEAIRCGQYYVNHRWLGGMLTNWGTVSSSIKTLMQYEKILNDEDSILTKKELGNIEKKKQKLDKALGGIREMGAIPDILFIIDTNKEHIAVKEAKKLGIPIVAILDTNSDPDGITYLIPGNDDSRKSIELYCKLATDSILAGIESSLAKSGVKIDDIRGDEFIQEKEDGIVQTKRRRSKVYKEEEREVVTNEDESR
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RECA_EDWI9
Sequence: MDENKQRALAAALGQIEKQFGKGSIMRLGDTQTLDIESISTGSLSLDVALGIGGLPMGRIVEIFGPESSGKTTLTLSVIACAQAAGKTCAFIDAEHALDPIYAAKLGVNVDDLLVSQPDTGEQALEICDALVRSGAVDVIIVDSVAALTPKAEIEGEMGDSHVGLQARLMSQALRKLTANIKNANCLVVFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGAIKEGDEVVGNETRVKVVKNKVAPPFRQAEFQILYGAGISKESELIDLGVKHKLLDKSGAWYSYNGDKIGQGKANSMKFLQENTTISAELEGKLRELLLSHAAATDAERAGAEREDNAAADDENF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O165_CONIM
Sequence: MKLTCMMIVTVLFLTAWIFITADNSRNGIENLPRMRRHEMKNPKASKLNKRGCREGGEFCGTLYEERCCSGWCFFVCV
What are the official names of this protein?
Conotoxin 5.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IRAM_ECOBW
Sequence: MKWIVIDTVIQPTCGISFSAIWGNMKMIIWYQSTIFLPPGSIFTPVKSGIILKDKEYPITIYHIAPFNKDLWSLLKSSQECPPGESKITNKCLHNSCIIKICPYGLK
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation.
What are the official names of this protein?
Anti-adapter protein IraM.
What is the protein family that this protein belongs to?
Belongs to the IraM/RssC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_PROM2
Sequence: MTDILNYNKSEEIFSAAQQLMPGGVSSPVRAFKSVGGQPIVFDRVKGPFAWDIDGNRYIDYIGSWGPAICGHAHPEVTTALQEAIEKGTSFGAPCVLENKLAEMVIDAVPSVEMVRFVNSGTEACMAVLRLMRAFTGRDKVIKFDGCYHGHADMFLVKAGSGVATLGLPDSPGVPRTTTANTLTAPYNDLEAVKKLFSENPDAISGVILEPIVGNAGFITPEPGFLEGLRELTTENGSLLVFDEVMTGFRISYGGAQEKFGVTPDLTTLGKVIGGGLPVGAYGGKKEIMSMVAPSGPVYQAGTLSGNPLAMTAGIKTLELLKQDGTYDKLDSTTSRLIEGIIQSAENNGIAINGGSISGMFGFFLCDGPVRNFEEAKTNNSELFGKLHREMLQRGIYLAPSPFEAGFTSLAHSEDEIDQTIEAFDESFNAIKN
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSN7_MOUSE
Sequence: MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLDHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV
What is the function of this protein?
May be involved in cell proliferation and cell motility.
What are the official names of this protein?
Tetraspanin-7, Tspan-7, Cell surface glycoprotein A15, PE31, TALLA homolog, Transmembrane 4 superfamily member 2.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NECT4_MOUSE
Sequence: MPLSLGAEMWGPEAWLRLLFLASFTGQYSAGELETSDVVTVVLGQDAKLPCFYRGDPDEQVGQVAWARVDPNEGIRELALLHSKYGLHVNPAYEDRVEQPPPPRDPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTQSSRSFTHPRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDRRITHTLQVAFLAEASVRGLEDQNLWQVGREGATLKCLSEGQPPPKYNWTRLDGPLPSGVRVKGDTLGFPPLTTEHSGVYVCHVSNELSSRDSQVTVEVLDPEDPGKQVDLVSASVIIVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRTEEDDDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV
What is the function of this protein?
Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1.
What are the official names of this protein?
Nectin-4, Ig superfamily receptor LNIR, Nectin cell adhesion molecule 4, Poliovirus receptor-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, adherens junction.