PharMolix/UniProtQA huggingface dataset:
Protein: RL20_FRATM
Sequence: MSRVKRGVTARARHKKVLNQAKGYYGARSRVYRVAKQAVIKAGQYAYRDRKVKKRTFRSLWIVRINAAARQHDISYSQLINGLNKAGVELDRKALAELAVYNKDAFAAVVEKAKAALAYII
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RIP2_BRYDI
Sequence: MRSIGFYSVLALYVGAHVTEDVDINFSLIGATGATYKTFIRNLRTKLTVGTPRVYDIPVLRNAAAGLARFQLVTLTNYNGESVTVALDVVNVYVVAYRAGNTAYFLADASTEANNVLFAGINHVRLPYGGNYDGLETAAGRISRENIELGFSEISSAIGNMFRHNPGTSVPRAFIVIIQTVSEAARFKYIEQRVSENVGTKFKPDPAFLSLQNAWGSLSEQIQIAQTRGGEFARPVELRTVSNTPTFVTNVNSPVVKGIALLLYFRVNVGTDNVFAMSLSTY
What is the function of this protein?
Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells.
What are the official names of this protein?
Ribosome-inactivating protein bryodin II, BD2, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: TEX44_MOUSE
Sequence: MTAEPLEDPEASSSSTHDLPEASSDNTADENSADLPGESEGPDSLPDDVPPGDIDEVLAEHDVDQTSEAKAITTEQNEEQDFIRTDTFMRQDEDLLSKQISTITEKNVDQAYMQINTVFEQDKDQASIQTATLMGQDEDQAFLQIVTSVGQNKDQASIQTATLMGQDEDQASLQIATSVGQNKDQPSMQMDTSIGQDVEPAISTDTATSAVKDESPDIPHQGQDNPEETTSLLPQDPGILQVFVGFQNPVWDRLAENNRTSRSRTVSPSDSQTQEKTLGNPNVPEGQPVLVPNADVLSNLPEHVQTSVGAADPPPSDTSGRDPEPTPTTNSAKQEAEGFKALNPGSKARSPGLTSEDSAADSGIPPDPPDPGSPGGSPPHSPDFYQVALGRNLLDPNLYRPDVENDYMRSMTSLLGCGEGSISSLTDILVWSDTATRMGVAVGILASGCSSPADRLQDEGPRLRTVASLLRSARSAFSSGVMSGTGSALHSVTHLLESVERRTMEGIRSAMRYLAHHLTSRWARTGPSGN
What are the official names of this protein?
Testis-expressed protein 44.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y364_METJA
Sequence: MGSMIEINFSHDYFKLREQRFTTIRSKHYLKNKGLRVGDVVKIKHPSGEFPAKIVGVEVKRICDIPLEILKKDAEFEGFNIKTHQDFVDLLNSFIPYKSNKLTTEKAIIYLERV
What are the official names of this protein?
Uncharacterized protein MJ0364.
Protein: M2_I57A1
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCNYRFFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: RS14_CUPTR
Sequence: MAKLALIEREKKRAKLVAKYAAKRANLKAIIDDQEKSEEERYSARLELQQLPRNANPTRQRNRCAITGRPRGTFRKFGLARNKIREIAFKGEIPGLTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RK36_ORYNI
Sequence: MKIRASVRKICTKCRLIRRRGRIRVICSNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HISXH_RHIME
Sequence: MTLRPQLARYKDKTMTSVSFYEYSKLNAEEKAALLRRSETDISGFIEKVAPILEAVRTEGDKALARFGRELDKADVTEANLKVTAAEFDAAFKLVDASVLESVQFGIDNIRKFHEEQKPEAMWLKEIRPGAFAGDRFTPIQSVALYVPRGKGSFPSVTMMTSVPAVVAGVPNLAIVTPPAPDGSVDAATLVAARLAGVETVYKAGGAQAVAAVAYGTETVKPALKIVGPGSPWVVAAKRSLSGVIDTGLPAGPSEVMILADDTVHGGLAALDLLIEAEHGPDSSAYLVTHSGRVAEEALAALPEHWARMTEQRTAFSKTVLSGKTGGIVLTSSIEESYEFVNAYAPEHLELLSEQPFIHLGHITEASEILMGTHTPVSIANFSLGPNAVLPTSRWARTFGPLSVTDFVKRSSIGYVTAPAYPEFARHSHNLAIYEGFSSHALAVSPVRDAYLKKGA
What are the official names of this protein?
Histidinol dehydrogenase homolog.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: SCPB_LISIN
Sequence: MNREEQLGVLESLLFAAGDAGLSTEQLTEVMEITHIEALNLLELLSERYNGNEDRGLILLELAGTFQLATKKAHAEFLRKLVEVPSNTVLSQASLETLAIIAYRQPVTRMEVDEVRGVQTDGPIRTLVAKGLVTDKGRVDGAGRAKLYVTTSEFLDAFGLNSLDDLPKLADPEAEDPDQSEMDLFFDRFNQSKEQEEE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: ASTB_SALPB
Sequence: MTAHEVNFDGLVGLTHHYAGLSFGNEASTRHRFQMSNPRLAVKQGLLKMKALADAGFPQAVIPPHERPFIPALRQLGFTGSDEQILDKVARQAPRWLSSVSSASPMWVANAATVCPSADALDGKVHLTVANLNNKFHRALEVPVTEALLRAIFRDESQFSVHSALPQVALLGDEGAANHNRLGGEYGSAGVQLFVYGREEENEIRPARYPARQSREASEAVARLNQVNPQQVIFAQQNPEVIDQGVFHNDVIAVSNRQVLFCHEAAFARQKVLINQLRTRVDGFMAIEVPAGEVSVSDAVATYLFNSQLLSRDDGSMLLVLPRECQDHAGVWRYLNKLVAEDNPISAMQVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDALFTALNAWADRYYRDRLTAADLADPLLLREGREALDVLTRLLDLGSVYPFQQTGAADG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: PDRP_RHOPA
Sequence: MLTDGSYFHLHLVSDSTGETLITVSRAVTAQYANVTPVEHVYPLVRSQKQLDRVLQEIEEAPGIVLFTLLETELVNRLEAKCQEINSPSLSIIGPVMQLFEAYLGASTMGRVGAQHTLNAEYFQRIDALNYSMMHDDGQHVEGLEEADVVLVGVSRTSKTPTSIYLANRGIRTANVPLVAGIPIPHQLETLKKPLVVSLHASPERLIQVRQNRLLSLGAGSGNDSYIDRQAVTDEVLLARKLSAKYGWSLLDVTRRSIEETAAAIMKLLADRQRQRVPE
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: PLE4_CLIPA
Sequence: MRIPNVFLSYLRQVAVDGTLSSCSGVKSRKPVIAYGFDDSQDSLVDENDEKILEPFGYYRHLLKGKSARTVLMHCFNAFLGLPEDWVIGVTKAIEDLHNASLLIDDIEDESALRRGSPAAHMKYGIALTMNAGNLVYFTVLQDVYDLGMKTGGTQVANAMARIYTEEMIELHRGQGIEIWWRDQRSPPSVDQYIHMLEQKTGGLLRLGVRLLQCHPGVNNRADLSDIALRIGVYYQLRDDYINLMSTSYHDERGFAEDMTEGKYTFPMLHSLKRSPDSGLREILDLKPADIALKKKAIAIMQDTGSLVATRNLLGAVKNDLSGLVAEQRGDDYAMSAGLERFLEKLYIAE
What is the function of this protein?
Geranylgeranyl pyrophosphate synthase; part of the gene cluster that mediates the biosynthesis of pleuromutilin, a tricyclic diterpene showing antibacterial properties (PubMed:27143514, PubMed:29388775).  The geranylgeranyl diphosphate (GGPP) synthase catalyzes the first step in pleuromutilin biosynthesis (PubMed:27143514, PubMed:29388775).  GGPP is then substrate of the premutilin synthase (PS) to yield premutilin (PubMed:29388775).  Premutilin synthase is a bifunctional enzyme composed of the fusion of a class II diterpene cyclase (DTC) and a class I diterpene synthase (DTS), with the corresponding domains and active sites containing characteristic aspartate-rich motifs.  GGPP is first converted to mutildienyl-diphosphate (MPP) at the class II DTC site (PubMed:29388775).  MPP is subsequently further cyclized at the class I DTS site, followed by a 1,5-hydride shift and addition of water prior to terminating deprotonation, to yield premutilin (PubMed:29388775).  In addition to the aforementioned GGPP synthase and bifunctional diterpene synthase, the cluster contains also three cytochrome P450 monooxygenases, a short-chain alcohol dehydrogenase, and an acyltransferase, involved in the conversion of premutilin to pleuromutilin (PubMed:27143514, PubMed:29388775).  The cytochrome P450 monooxygenases P450-1 and P450-2 hydroxylate premutilin at C-11 and C-3, respectively, producing 11-hydroxypremutilin and 3-hydroxypremutilin (By similarity).  The combination of the actions of both ple5 and ple6 leads to the production of 3,11-dihydroxypremutilin (By similarity).  The short chain dehydrogenase SDR further converts 3,11-dihydroxypremutilin into mutilin (By similarity).  The acetyltransferase ATF then acetylates mutilin to produce 14-O-acetylmutilin (By similarity).  Finally, the cytochrome P450 monooxygenase P450-3 catalyzes hydroxylation on the alpha position of the acetyl side chain of 14-O-acetylmutilin to yield pleuromutilin (By similarity).
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, GGS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, Pleuromutilin biosynthetic cluster protein synthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: RPC1A_CHLRE
Sequence: MHYKKYAELLKNGTYFSHIHSPTLLYPKGKVMYAQYGNSPLQGLNSQVTNLNLIRKVVAASAEMDSFKKLPNLQNNKLPLNNLKARLNTKAIYISNEEAQLTVSKIGTPNAIETDVPGTIKNAPSNTLLTHRSFKFFVNKIYAKPLISLKKTKETKPLLLGKTGTTLTQKGLNPFQSLFLNTKSSSPSTARSFGTKNIVNTLQIKKIVHKFENSYSKLTEINLITINLASANRIRQWAEKTLPNGKVVGEVINPETIHYKTLKPIKGGLFCERIFGPLKDHECACGKKFNIKNYLTKTVNNSSIQPIAESRQTQPNTQLSLNLQKRYFCRICDVEYTYSIIRRTQLGYIQLASPTTHVWFVKGIPSYISILLDMKKKHLQGITYNTETLTLENSFRGRQLLPVSPSSIFESWQKIMKKQYPEKYNLTNTMIKIKSTNTLPLRVSQPNSNTSYSYMPNIYIPEGEGEEKTKTKLKKTTPLNAIAQKGVKYKKPKTKKALYKQYLKNYYARKPKNSNQAEAVSFGVNKVQLPLTAFQQRNKVYFYKSEKRNWPVLTTVAKMQYIVSKKGWFKLIQYVIKSAESYGAATPTKMDGLQKMSLLTKQA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta' N-terminal section, PEP, Plastid-encoded RNA polymerase beta' N-terminal section, RNA polymerase beta' N-terminal section.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPG_FRATT
Sequence: MSNAREIRSKVQSVKNTQKITGAMELVAASKMRGAIVKMNNVRPYVESANTIIKNVTAASIDYPNPYLFDRDVKRVGYIVISTDRGLCGGLNINLFKHVLKEIKNNIEDRVGVDVCVIGSKAENFFAKLKDVNIVATAHYNDKDKEGSIRAIGGAVKVMLDKFTAGEIDRLYMSSNQFVSTIKQRPRLQTLLPIQDIFSAEEIKANKEKATKGHWDYIYERDIEEVLNALFIRYIEAQVRGAILENAACEQAARMMAMKNATDNASDIIDQLKLDYNKVRQAMITQELAEICSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PKH4B_HUMAN
Sequence: MEALRNPMPLGSSEEALGDLACSSLTGASRDLGTGAVASGTQEETSGPRGDPQQTPSLEKERHTPSRTGPGAAGRTLPRRSRSWERAPRSSRGAQAAACHTSHHSAGSRPGGHLGGQAVGTPNCVPVEGPGCTKEEDVLASSACVSTDGGSLHCHNPSGPSDVPARQPHPEQEGWPPGTGDFPSQVPKQVLDVSQELLQSGVVTLPGTRDRHGRAVVQVRTRSLLWTREHSSCAELTRLLLYFHSIPRKEVRDLGLVVLVDARRSPAAPAVSQALSGLQNNTSPIIHSILLLVDKESAFRPDKDAIIQCEVVSSLKAVHKFVDSCQLTADLDGSFPYSHGDWICFRQRLEHFAANCEEAIIFLQNSFCSLNTHRTPRTAQEVAELIDQHETMMKLVLEDPLLVSLRLEGGTVLARLRREELGTEDSRDTLEAATSLYDRVDEEVHRLVLTSNNRLQQLEHLRELASLLEGNDQQSCQKGLQLAKENPQRTEEMVQDFRRGLSAVVSQAECREGELARWTRSSELCETVSSWMGPLDPEACPSSPVAECLRSCHQEATSVAAEAFPGAGVAVLKPHALGKPWASQQDLWLQYPQTRLRLEEALSEAAPDPSLPPLAQSPPKHERAQEAMRRHQKPPSFPSTDSGGGAWEPAQPLSGLPGRALLCGQDGETLRPGLCALWDPLSLLRGLPGAGATTAHLEDSSACSSEPTQTLASRPRKHPQKKMIKKTQSFEIPQPDSGPRDSCQPDHTSVFSKGLEVTSTVATEKKLPLWQHARSPPVTQSRSLSSPSGLHPAEEDGRQQVGSSRLRHIMAEMIATEREYIRCLGYVIDNYFPEMERMDLPQGLRGKHHVIFGNLEKLHDFHQQHFLRELERCQHCPLAVGRSFLRHEEQFGMYVIYSKNKPQSDALLSSHGNAFFKDKQRELGDKMDLASYLLRPVQRVAKYALLLQDLLKEASCGLAQGQELGELRAAEVVVCFQLRHGNDLLAMDAIRGCDVNLKEQGQLRCRDEFIVCCGRKKYLRHVFLFEDLILFSKTQKVEGSHDVYLYKQSFKTAEIGMTENVGDSGLRFEIWFRRRRKSQDTYILQASSAEVKSAWTDVIGRILWRQALKSRELRIQEMASMGIGNQPFMDVKPRDRTPDCAVISDRAPKCAVMSDRVPDSIVKGTESQMRGSTAVSSSDHAAPFKRPHSTISDSSTSSSSSQSSSILGSLGLLVSSSPAHPGLWSPAHSPWSSDIRACVEEDEPEPELETGTQAAVCEGAPAVLLSRTRQA
What are the official names of this protein?
Pleckstrin homology domain-containing family G member 4B, PH domain-containing family G member 4B.
Protein: WWOX_CHICK
Sequence: MAALKYAGLEDTDSEEELPPGWEERTTKDGWVYYANHLEEKTQWEHPKSGKRKRVAGGLPYGWEQETDENGQVYFVDHINKRTTYLDPRLAFTVEDNPAKPPTRQKYDGNSTAMEILQGRDLSGKVIIITGANSGIGFETAKSFALHGAYVILACRNMSRGNDAVQRILEEWHKAKVEAMTLDLASLRSVQNFAEAFKSKNMPLHILVCNAAIFGSSWCLTEDGLESTFQVNHLGHFYLVQLLEDILRRSSPARVVVVSSESHRFTEIKDSSGKLDFSLLSPSKKEYWAMLAYNRSKLCNILFSNELNRRLSPHGVTSNSVHPGNMIYSSIHRNWWVYTLLFTLARPFTKSMQQGAATTVYCATAAELEGLGGMYFNNCCRCLPSAEARNELTAVALWELSERLIREQLGRRSP
What is the function of this protein?
Putative oxidoreductase.  Acts as a tumor suppressor and plays a role in apoptosis.  May function synergistically with p53/TP53 to control genotoxic stress-induced cell death.  Plays a role in TGFB1 signaling and TGFB1-mediated cell death.  May also play a role in tumor necrosis factor (TNF)-mediated cell death.  Required for normal bone development.  Inhibits Wnt signaling (By similarity).
What are the official names of this protein?
WW domain-containing oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL24_LEPIN
Sequence: MAKLTYRGSEYTKFKKFRIKKNDEVICITGKHKGKRGKVLSIDKKRDRVIVEGLNKRKRFMRPTQENPQGGVIEVEAPIHISNVMFYDPKKKKKAGVRVGFETVKGKKVRVSRPDKKEL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: HIR3_KLULA
Sequence: MSSFAALNLSTNENADESKDHSRELQVEESSKIFQLALIQLKAKRFDDAKETFDRLFEIDVIKPNKWGLYEYSSPTLDSLRYLAYRNRGILHYQYAKENFKQMESDDVVEHILKTLECLLESLQHGEADNTVTHLLLKIFWSFNSTKLSRTILEYELTRSPEEIRLLSSLSAMFKDQKRVFKQYSQLLKKLHVTSLPQNIPTAVEAVLNCIETCDVEEGQIEPLLKDIKAMKTEDDEILKELDGSNLNLNELSWEELGVSLRSLVPKTKVVNILGRKSDTYSDLEAPIEYVSFTTDEFMEKLSDSSNESPGHSPEHFEDAVSVMPETNNIEVSVEREPSAKRQDSTDRPAQRSSKRFKEREKVQEPDVEQQVEFHTYIINEINQSLHVSGIEKDISIEELDPNNVAKRQELCMSDFYDCLTSWTNKHTEFLKQGQENFSVKGSTDDFTQLTMLLRSSMFSGDVEPTDSLSEIEAEDVRRFIRDVNDKKLHFHAVRFLFIKELLKLREDGTCLVTDYFWSPALYEVVEFFSMAIEVNLYQMIEPSTDESTVSIAVSIFEIMTNMMGNICNDLANKKAQGQKYNELESQRNKLQRKIVRWYEMLLSKPLSTKLKFRFQWSHFSCLQCTTDVTNSTLITTIEDIENSLKEFPDFGTVAYSNYNNISSLSLKTVQSQFSKIKMLRRFTIVDIENEDEDNTHKDYIEHLYCILNQIPCEGTDFQSLLSFVNTSPFLMKLKLWKLLLNYFASRKDQLRFQNCFFSSIKFLLARLSSEEYQIQSQLQRQQTLLSTLTHIGEFSKRFFQVLCDNWDMSLKNPSRDQLQVLVSIFRLLYPLVFYETLTEKNASLKSFFKKAVKSSITIQDIFLTVASLMILCHKFITLEKENAKEEFTGSIIDLISALHMLAGKFEFCDRFDGNFLKVQEKLLCEFSNDSAFTHLKRELWCRYHISIGLDNPEDQHQTHAQPMVKANAIMLSNYFIKFQYQDRNILVLSNNRSNFKQFFETVMELIGDIDYEANHVLSRNEYFFNQYFTAPITLKTIRDAYAGEFEIEFTSPNDDLQSGVDGGLFYVSAVHALNQYKARKKSMQARPSELDAIISTLTTDILYNTKRFESWYLLGKCYSFVVEDDLTWTSDKLASRDKKQATAFAEKKAILCYLMALSLYLSTFKETTSEQMKNDNKIVFRNLLESLGKEMLQAYVKPMSSMSYTWKLKPVLVLKADGSLENLPISYKPSISETNILRCILMILAKADTLYNKDEERNWMNPFYISKVHFKTDRKLFKESGICLLQDSCRLALLQSSVSGSDNILEAHYALVSYCYKCFKDRTFSLAEAISHLREDNGFFGLPEEEWQVEDDKSFFNLIIRLLKYILSKDKQKWQHRPIYRIAQIKYTEFEDTDGAMKEMNKLLALKSVNKNVVNIWKPENELPGKHFVYAYQYVLFYMDLLNEKHDFMAIGGMVKKLRRFGSGMINSQDAINKAVELFVNGAKVKLSLNEKEHGELLMQRIPFPEFVELSEELFNAFKKGDYQSDVLDVFLLAYNLKKGTNSIQFDGVCITIYFKYFYCPFVENKKQSTPYPAPIIEGISGPQPENSPSQQLPQSQSQPQLPRSPSPNTANNKEKTAKTPVKNPTSIRKRVSKRDVFDRVVKLIEKRLS
What is the function of this protein?
Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.
What are the official names of this protein?
Histone transcription regulator 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the HIR3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ILVD_SULIM
Sequence: MPAKLNSPSRYHGIYNAPHRAFLRSVGLTDEEIGKPLVAIATAWSEAGPCNFHTLALARVAKEGTKEAGLSPLAFPTMVVNDNIGMGSEGMRYSLVSRDLIADMVEAQFNAHAFDGLVGIGGCDKTTPGILMAMARLNVPSIYIYGGSAEPGYFMGKRLTIEDVHEAIGAYLAKRITENELYEIEKRAHPTLGTCSGLFTANTMGSMSEALGMALPGSASPTATSSRRVMYVRETGKALGSLIENGIKSRDILTFEAFENAITTLMAMGGSTNAVLHLLAIAYEAGVKLTLDDFNRISKRTPYIASMKPGGDYVMADLDEVGGVPVVLKKLLDAGLLHGDVLTVTGKTMKQNLEQYKYPNVPHSHIVRDVKNPIKPRGGIVILKGSLAPEGAVIKVAATNVVKFEGKAKVYNSEDDAFKGVQSGEVREGEVVIIRYEGPKGAPGMPEMLRVTAAIMGAGLNNVALVTDGRFSGATRGPMVGHVAPEAMVGGPIAIVEDGDTIVIDVESERLDLKLSEEEIKNRLKRWSPPSPRYKSGLLAKYASLVSQASMGAVTRPA
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SYGB_VIBC3
Sequence: MAKEFLIELGTEELPPKQLRTLAEAFAANFAAELATADIAHEGVTWFATPRRLALKVANLAESQPDRVVEKRGPAVNVAFDADGKPTKAAEGWARGNGITVEQAERLVTDKGEWLLFKEQVQGQQTASVVVEMAAKALANLPIAKPMRWGDKETQFIRPVKTLTILFGSELIQGEILGVASARTLRGHRFMGEAEFTIESAEQYPAILEERGKVIADYATRKAMIIEGSQQAAQQLGGIADLEDALVEEVTSLVEWPVVMTAKFEEKFLKVPAEALVYTMKGDQKYFPVYDASKKLLPNFIFVSNIESKEPRHIVEGNEKVVRPRLADAEFFFNTDRKRPLVDRLPLLENAIFQQQLGTIKDKTDRITELAGYIAEQIGADVEKSKRAGLLAKCDLMTSMVFEFTDTQGVMGMHYARHDGEAEEVAVALNEQYMPRFAGDELPSRGVSAAVAMADKLDTIVGIFGIGQAPKGSDPFALRRASLGVLRILVEYGYQLDLVDLIAKAKSLFGDRLTNANVEQEVIEFMLGRFPTWYQDAGFSIDIIQAVLARNPTKPADFDQRVKAVSHFRALEEAEALAAANKRVGNILAKYDGELGEEIDLALLQEDAEKALAEAVEIMAEALEPAFATGNYQEALSKLAGLRAPVDAFFDNVMVMADDEALKKNRLTLLNKLRNLFLQIADISLLQK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_PSEAE
Sequence: MKHHLTPLDATQLDSWRALAAHRQELQDFRMRQAFIDDPERFKRFSFSACGLFLDFSKNLIRQDTIDLLVKLAEEARLSDAIRAMFDGEAINASERRPVLHTALRRPIGDKVLVDGVDVMPEVHRVLHQMTELVGYVHNGLWRGYTEKPITDVVNIGIGGSFLGPQLVSEALLPFAQKGVRCHYLANIDGSEFHELASRLNAETTLFIVSSKSFGTLETLKNAQAARAWYLAQGGTEEELYRHFIAVSSNKEAAIAFGIREENIFPMWDWVGGRYSLWSAIGLPIAMSIGISNFKELLSGAYNMDQHFQTAPFERNIPVLLGLLGVWYGDFWGANSHAILPYDYYLRNITDHLQQLDMESNGKSVRQDGTPVTSGTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPVSSYNPVADHHQWLYANCLSQSQALMLGKSREEAEAELRAKGLPEAEVQRLAPHKVIPGNRPSNTLVVERISARRLGALIAMYEHKVYVQSILWGINAFDQWGVELGKELGKGVYSRLVGSEETPAEDASTQGLIDFFRGRHRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATF_METMA
Sequence: MELAVIGKSEFVTGFRLAGISKVYETPDIPATESAVRSVLEDKSVGILVMHNDDIGNLPEVLRKNLNESVQPTVVALGGSGSGSTSLREKIKQAVGVDLWK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: RNH_XANOM
Sequence: MKSIEVHTDGSCLGNPGPGGWAALLRYNGREKELAGGEAVSTNNRMELMAAIMALETLTEPCEIVLHTDSQYVRQGITEWMPGWVRRNWKTAGGDPVKNRELWERLHAATQRHRIDWRWVKGHNGDPDNERVDVLARNQATAQRDGRATS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIMD_BPPH1
Sequence: MGSPEKLRPSDFSKSFLISSIRFAMSFSSFELYSACSSLIRVSSPTMAET
What are the official names of this protein?
Uncharacterized immunity region protein 13.
Protein: CPS5_ISORU
Sequence: NQLADGSWGDAGTFSIFDRILNTLACVVALRSWNIHPHKTDKGIWFMKKNMCRIDEENLEHMPIGFEVALPSLIDIAKKLEIDIPTQTRGLQEIYARREIKLKKIPRDIMHQVPTTLLHSLEGMAGLKWEKLLKLQSEDGSFLFSPSSTAFALQQTRDHNCLKYLTNHIHKFNGGVPNVYPVDLFEHLWAVDRLQRLGLSRYFEPEIEECIAYVHRQWTEKGICWARNSQVEDIDDTAMGFRLLRLHGYEVSADVFRHFKSDGGEFFCFKGQSTQAVTGMYNLYRASQLMFPGENILVDAARFSANFLQLKRAKNDLLDKWIITKDLPGEVGYALDVPWYASLPRVETRFYLDQYGGDDDVWIGKTLYRMPYVNNNKYLELAKLDYNNCQALHQQEWQNILKWYRSCSLGEFGMTERSLLQTYYVAAASVFEPEKSQERLAWAKTAILMETITSHFEFQQLSRDQKRAFITEFEHDSILKYTNGGRYKRRSSLVGTLVRTLNHLSLDILLAHGRDIHQPLKNAWCKWLNSWEEGGDAELLVRTLNLMSGGGRRRRWASEELLSSNPKHEQLLKATIGVCDKLRLFLRRKVQGGNGCMNATGMTTVEIESEMRELVKLVVTRSSSEDLDSEIKQNFLTIARSFYYAAYCNQGTINFHIAKVLFEK
What is the function of this protein?
Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities (PubMed:28381502).  Catalyzes the conversion of (2E,6E,10E)-geranylgeranyl diphosphate (GGPP) to ent-copalyl diphosphate (ent-CPP) (PubMed:28381502).
What are the official names of this protein?
Ent-copalyl diphosphate synthase 5, Putative ent-copalyl diphosphate synthase, IrTPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsc subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YQJA_ECOLI
Sequence: MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLPAAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNWLSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMSGLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGNRG
What is the function of this protein?
May be a membrane transporter required for proton motive force (PMF)-dependent drug efflux.  Required, with YghB, for the proper export of certain periplasmic amidases and, possibly, other Tat substrates.  May play a role in determining membrane lipid composition.
What are the official names of this protein?
Inner membrane protein YqjA.
What is the protein family that this protein belongs to?
Belongs to the DedA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.