PharMolix/UniProtQA huggingface dataset:
Protein: PUR2_METM6
Sequence: MKVLLIGGGAREHAIAMALKKNELVELYTLMKNKNPGIYSLSEEVSFNSETDVPAIKEFAEKIKPEIAVIGPESPLGVGAADLLEEMGIPTVGPKKLPAQIETSKEFMRNLFKKYEIDGSLKYAAFNNYGNDLETFIDEMTSLGKDVVVKPAGLTGGKGVKVVGEQLKDNEEAKIYAKEVFDKSIGGGNIIIEEKLVGVEFTLHGFVDGENITFMPAVQDHPHAYNNDEGPITGGMGSYSCPNHGLPFLSEEMLDRAEKIMEKTVNSINLEVGPYKGFLYGQFMLTADGPKIIEYNARFGDPEAMNLLPILKTDFLDVCFAIAEGKLDKMNIEFENKATVCKYVVPNGYPIDPVKNKELTVDKKAIENANAVLFYASINEENGKLYITGSRSAAVVGISEKIEEAEKIAQKAIKNFKGEVYYRSDIGTLDLIKKRIDRVKKLAK
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: RL2_STRS7
Sequence: MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRNNNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPDADIKIGNALPLANIPVGTVVHNIELKPGKGGELVRAAGASAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: URK_LISMH
Sequence: MTKKPIVVGVTGGSGSGKTSVTKAICDHFSGHSILMIAQDVYYHDQANISFEDRLKVNYDHPLAFDTDLLISHIAALRRYETIEKPIYDYAKYTRKKEVEIQEPREVIILEGILILEDKRLRDLMDIKVYVDTDDDIRFIRRLLRDMKERGRTMDSVIEQYLSVVKPMHNEFIEPTKKFADIIIPEGGENHVAIDLMTTKIESILQKHV
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URGT6_ARATH
Sequence: MAPVSKADKKAAVDAAAWMFNVVTSVGIIIVNKALMATYGYSFATTLTGLHFATTTLMTLVLRCLGYIQPSHLPFTELLRFILFANFSIVGMNVSLMWNSVGFYQIAKLSMIPVSCLLEMVFDKIRYSRDTKLSIGLVLVGVGVCTVTDVSVNTKGFVAAFVAVWSTALQQYYVHYLQRKYSLNSFNLLGHTAPAQAATLLVVGPFLDYWLTEKRVDMYDYNLVSVLFITLSCTIAIGTNLSQFICIGRFTAVSFQVLGHMKTILVLIMGFFFFGREGLNLHVVVGMIIAVLGMIWYGNASSKPGGKERRNYSLPTTRQQKLGAASDSDDNEDKA
What is the function of this protein?
Nucleotide-sugar transporter that transports UDP-rhamnose or UDP-galactose and UMP in a strict counter-exchange mode.
What are the official names of this protein?
UDP-rhamnose/UDP-galactose transporter 6, UDP-Rha/UDP-Gal transporter 6, Bi-functional UDP-rhamnose/UDP-galactose transporter.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: SYL_GRABC
Sequence: MTDSITDLQSDQRPDRSYDFASAERRWQLAWTERACFTVPDVPDPGARTYYVLEMFPYPSGQIHMGHVRNYTLGDVVARYKRAQGYQVLHPMGWDAFGLPAENAARERGVHPGQWTWNNIAAMRGELQRMGLSITWEREFATCDPSYYGHQQALFLDFLKKNLVERRESWVNWDPVDETVLANEQVIDGKGWRSGAPVERKKLSQWFLRITDYAEELLAGLDQLDRWPERVRVMQSRWIGRSEGARLRFPLVEPLGDQREIEVYTTRPDTLYGMSFVAIAADHPVAAALAAHHPALAAFVAECRSLGTSEAAIEAAEKRGFDTGLRVKHPFCDETFPVWIANFVLMDYGTGAVFGCPAHDQRDLDFARKYDLSVTPVVLPSDQDAASFTIGRKAYDGDGILFNSGPFDGLTPDAARREAITRLEAMGWGQGVTNWRLRDWGVSRQRYWGCPIPIIHCDQCGPVPVPADQLPVTLPEDVTFDRPGNPLDHHPSWKHVTCPSCGAAAVRETDTFDTFVDSSWYFARFASPHAHVPVLKEAAQNWLPVDQYIGGIEHAILHLLYARFFTRAMADTGHVPVREPFAGLFTQGMVTHESYRAADGRWLSPVEVTRHGETVVETATGEPVQVGRGEKMSKSKRNTVAPGEIFNRYGADAARWFILSDNPPERDMEWTDAGAVGAYRFVQRLYRLAEAVARIAKEETNRDDASSDAAMTLRRMTHRTVAAVTEALEGFNFNVAVARVYEFANALTEAEKKAAEPGMTAARVEAITLLSRIIAPMMPHLAEEMATLIEQGPKLVAEQVWPSADPALLVVQSVTIAIQVMGKLRATLDISPDADQDSVIAQAEADPNVVRALEGKRVVKRIYVPNRIVNFVIAG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNT2_ASPOR
Sequence: MGMLALGAMQLAAGAVFEFPSCPKDIPFSCQNSTAVADSCCFNSPGGALLQTQFWDTNPPSGPSDSWTIHGLWPDNCDGSYGQFCDKSREYSNITAILQEQGRTELLSYMKKYWPNYEGDDEEFWEHEWNKHGTCINTIEPSCYKDYSPQKEVGDYLQKTVDLFKGLDSYKALAKAGIVPDSSKTYKRSEIESALAAIHDGKKPYISCEDGALNEIWYFYNIKGNAITGEYQPIDTLTSPGCSTSGIKYLPKKSENSTASAWKFRSDKASQSVRFN
What are the official names of this protein?
Ribonuclease T2, RNase T2.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: MURG_ECO7I
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: JZ47B_CHIGU
Sequence: MRTLTLIAIVTCAALVIFHAAAAEELEAQDVIQPEDIFTGVATLEEDRIFECSFSCDIKKNGKPCKGAGEKKCSGGWRCKMNFCVKF
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Cg1b, U3-TRTX-Cg1b, Jingzhaotoxin-47.2, JZTX-47.2, Peptide F6-10.40.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 03 (juruin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GCKR_RAT
Sequence: MPGTKRYQHVIETPEPGEWELSGYEAAVPITEKSNPLTRNLDKADAEKIVKLLGQCDAEIFQEEGQIVPTYQRLYSESVLTTMLQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREQTEDSALHGIEELKKVAAGKKRVVVIGISVGLSAPFVAGQMDYCMDNTAVFLPVLVGFNPVSMARNDPIEDWRSTFRQVAERMQKMQEKQEAFVLNPAIGPEGLSGSSRMKGGGATKILLETLLLAAHKTVDQGVVSSQRCLLEILRTFERAHQVTYSQSSKIATLMKQVGISLEKKGRVHLVGWQTLGIIAIMDGVECIHTFGADFQDIRGFLIGDHSDMFNQKDELTNQGPQFTFSQDDFLTSILPSLTETDTVVFIFTLDDNLTEVQALAERVREKCQNIQALVHSTVGQSLPAPLKKLFPSLISITWPLLFFDYEGTYVQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRIANSKLFWRALAMLQRFSGQSKARCIESLLQAIHFPQPLSDDVRAAPISCHVQVAHEKEKVIPTALLSLLLRCSISEAKARLSAASSVCEVVRSALSGPGQKRSTQALEDPPACGTLN
What is the function of this protein?
Regulates glucokinase (GCK) by forming an inactive complex with this enzyme (PubMed:23957911).  Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal (PubMed:10456334).  The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (PubMed:23957911).
What are the official names of this protein?
Glucokinase regulatory protein, Glucokinase regulator.
What is the protein family that this protein belongs to?
Belongs to the GCKR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Note=Under low glucose concentrations, GCKR associates with GCK and the inactive complex is recruited to the hepatocyte nucleus.
Protein: FLIP_RHIME
Sequence: MLRFATFIIAMMAMSGIAGAQSFPADILNTPVDGSVASWIIRTFGLLTVLSVAPGILIMVTSFPRFVIAFAILRSGMGLATTPSNMIMVSLALFMTFYVMAPTFDRAWRDGIDPLLKNEISETDAMQRMSEPFREFMVANTRDKDLQLFIDIAREKGQTVVVDEKVDLRAVVPAFMISEIRRGFEIGFLIMLPFLVIDLIVATITMAMGMMMLPPTAISLPFKILFFVLIDGWNLLVGSLVRSFI
What is the function of this protein?
Plays a role in the flagellum-specific transport system.
What are the official names of this protein?
Flagellar biosynthetic protein FliP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: UPPP1_HALH5
Sequence: MEWSQELWLLIKYLLLGLFQGFTEPIPVSSSGHLVLLQHFLGIEIEGLSFEVMVNFASLFAVIAIYRFDLLKLVKGSARYVLYQDAQGKGDFRISFYLLLATVPAVLAALLFKDWIETELKQLHVIAFALLITGMALWLIRHLNGRKQDGDITLKDALLVGLAQTAALIPGISRSGATIVAAMGLGWRQETALRFSFFLYIPISLGSGVLAISDIVQDPHFTALWIPYTIAFIGSFIASYVSLLWFMNIMRHGKLIYFALYCWLAGLIVLSLLS
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 1, Bacitracin resistance protein 1, Undecaprenyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
Protein: RS10_CUPNH
Sequence: MQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVKGPVPLPTRIQRFDILRSPHVNKTSRDQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKV
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: THII_ENTFA
Sequence: MKYTEIMVRYGELSTKGKNRKTFIMQLAQNVKRALADFPALKIHADRDRMHILLNGEDSEEVIPKLSKVFGIQNFSPSIRIEKEMPAIRAMVQEVVREVYTPGKTFKITAKRSDHSFELDSNGLNQELGGAVIEAIPEIQVQMKKPDINLRIEIRKDAAYLSYETIRGAGGLPVGTSGRGMLMLSGGIDSPVAGYLAMKRGVEVEAVHFASPPYTSEQALQKAKDLAEKLVPYVGTIQFIEVPFTEIQEEIKRVVPQGYLMTITRRLMLRLTDAIREMRKGLVIINGESLAQVASQTLQSMVAINEVTSTPIIRPVVSMDKTEIIEIAEKIDTFELAIQPFEDCCTIFAPPQPKTRPRLDKAQEYEARLDLEGLMARALEGLKITEISAETAKDKQEDEFADFL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIRQ_STUST
Sequence: MRYLPVNAIEIPTTAGTPDAPFYQPLGNEEQLFQQAWQHGMPVLIKGPTGCGKTRFVQHMAHRLNLPLYTVACHDDLSAADLVGRHLIGAQGTWWQDGPLTRAVREGGICYLDEVVEARQDTAVVLHPLADDRRELFIERTGEALKAPPGFMLVVSYNPGYQNLLKGMKPSTRQRFVAMRFDYPPTAEEERIVANEAQVDAALAAQVVKLGQALRRLEQHDLEEVASTRLLIFTARMIRSGMTPRQACLACLAEPLSDDPQTVAALMDVVYVHFG
What is the function of this protein?
Activator of nitrite and nitric oxide reductases.
What are the official names of this protein?
Denitrification regulatory protein NirQ.
What is the protein family that this protein belongs to?
Belongs to the CbbQ/NirQ/NorQ/GpvN family.
Protein: YWCD_BACSU
Sequence: MYIIMGVFTTIVNIASFYILVEIMNVDYKAATVAAWILSVLFAYITNKLYVFQQKTHDLQSLLKELTAFFSVRVLSLGIDLGMMIILVGQFNTNETLAKILDNAVIVVVNYVASKWLVFKKTKEEGV
What are the official names of this protein?
Uncharacterized membrane protein YwcD.
What is the protein family that this protein belongs to?
Belongs to the GtrA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDGL_ECOL6
Sequence: MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAVLIAIIVAVITWCILLWSHFG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid.  Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
What are the official names of this protein?
Diacylglycerol kinase, DAGK, Diglyceride kinase, DGK.
What is the protein family that this protein belongs to?
Belongs to the bacterial diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TYEA_YERPS
Sequence: MAYDLSEFMGDIVALVDKRWAGIHDIEHLANAFSLPTPEIKVRFYQDLKRMFRLFPLGVFSDEEQRQNLLQMCQNAIDMAIESEEEELSELD
What is the function of this protein?
Involved in the control of Yop release.
What are the official names of this protein?
Protein TyeA.
What is the protein family that this protein belongs to?
Belongs to the TyeA family.
Protein: PETL_POPDE
Sequence: MPTLTSYFGFLLVALTITLVLFISLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: XPT_ACIAD
Sequence: MYALEQKILNEGIVLSDQVLKVDAFLNHQIDPVLMQQIGKEFAARFKDTGITKIVTIEASGIAPAVMAGLELGVPVIFARKYQSLTLKDDLYRSKVFSFTKQVESTIAISNKHINAEDKVLVIDDFLANGQAALGLIDLIHQANADIVGVGIVIEKSFQPGRDLLLEKGYRVESLARVASLTNGQVTFVIE
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPD_BRADU
Sequence: MRSYDFSPLWRSTIGFDRLFDLAESAQRATEDNYPPYNIERLGDDRYQISLAVAGFSPDEISVTAEQNVVTIEGNKTDKTEREFMYRGISTRAFKRQFNLADYVQVKNASFDNGLLKIELVREIPEAMKPRRIAINGATSDNLHKLESRAA
What are the official names of this protein?
Small heat shock protein HspD.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: NSCD_ARTOC
Sequence: MSSLPMFDSVSRFLPTANEDEQFWWKLTGRHMARMMHEAGYPEDRQVECLLFHRFKVVPCLGPRPHSDKPWYKSRVGGGAADGCPINYSWRFGTSDRKPHIRNFIEPLGALTNTPADPLNEVATKALLRDYSMTLPNVDLELFWTFAPHYRPRIIEKADMEKLAGASLLVGAEMSPDSRNIDIKAYMYPRVPSQTSQLLTTILPQAMRDAYGEDVCLDSLNLVRDFMTNDPEGSQLTLTGTTGIDCCKLQDTRVKIYVITRNTSFDHIAAIMTLGGRRPISEELLNQLRALWFELKGAPADFTSSEQLPAQTKPDGTKNPIVVPFYFDIQPRLALPDVKAYVDVSTSPVSDLAAAEAVVRHLERHGSGQNPKAYMNVLQDITPVEELETRKGALAFYSIAVKKNELDITSYFNPQVYKRYFAHEVQLNGQRRSAFE
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of neosartoricin B, a prenylated anthracenone that probably exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576, PubMed:23368997).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (By similarity).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (By similarity).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (By similarity).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (By similarity).  Neosartoricin B can be converted into two additional compounds neosartoricins C and D (By similarity).  Neosartoricin C is a spirocyclic compound that is cyclized through the attack of C3 hydroxyl on C14, followed by dehydration (By similarity).  On the other hand, neosartoricin D is a further cyclized compound in which attack of C2 on C14 in neosartoricin C results in the formation of the acetal-containing dioxabicyclo-octanone ring (By similarity).  Both of these compounds are novel and possibly represent related metabolites of the gene cluster (By similarity).
What are the official names of this protein?
Prenyltransferase nscD, Neosartoricin B biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: NET4_MOUSE
Sequence: MGSCARLLLLWGCSAVAAGLNGVAGANSRCEKACNPRMGNLALGRKLRADTMCGQNATELFCFYSENADLTCRQPKCDKCNAAHSHLAHPPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIMVFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAICTSRYSNPFPCTGGEVIFRALSPPYDIENPYSAKVQEQLKITNLRVRLLKRQSCPCQINDLNAKPHHFMHYAVYDFIVKGSCFCNGHADQCLPVEGFRPIKAPGAFHVVHGRCMCKHNTAGSHCQHCAPLYNDRPWEAADGRTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCNNCQHNTEGQHCQRCKPGFYRDLRRPFSAPDACKACSCHPVGSAILPFSSVTFCDPSNGDCPCKPGVAGPHCDRCMVGYWGFGDYGCRPCDCAGSCDPLTGDCISSNADVDWYHEVPAFHSMHNKSEPSWEWEDEQGFSALRHSGKCECKEQVLGNPKAFCGMKYSYVLKIKILSAHDKGSHAEVNVKIKKVLKSTKLKILRGKRTLYPESWTNRGCTCPILNPGLEYLVAGHEDVRTGKLIVNMKSFVQHWKPALGRRVMHILKRDCV
What is the function of this protein?
May play an important role in neural, kidney and vascular development.  Promotes neurite elongation from olfactory bulb explants.
What are the official names of this protein?
Netrin-4, Beta-netrin.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Protein: PLSX_BARBK
Sequence: MIRISVDVMGGDYGPEVTIAGAAIAQKHLPKVHFLFYGIDEAVEPVLKKYPDLLSVSHFYATESYTRMDEKPSQALRVGRGKSSMWHAIEAVKNGEADSCVSAGNTGALMAMSYFCLKMIAETERPGIAGIWPTLRNDSIVLDIGATIGASANQLVDFAVMGASMFRSLYNVEKTTIGLLNVGVEEVKGLDEIKKAGIILSKVQFEGLEYKGFIEGNDIGKGMVDVVVTEGFSGNIALKVAEGTAQQISELLKSAMRSSIFSRFGYLLSQSAFRKLKQKIDLDRVNGGVLLGLNGIVVKSHGSASASDFSSAIRIGYEMVNNELLKKIITDLQCFHEKKAIFLNNKGESVIDKETI
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: CCNE_HEMPU
Sequence: MSRRSGRLQSRQDNQPLTECISDENNLPMCTRKRKTREQDTTGVSKAEEVQRRRQQFTIENRWVPISESSSIETSLLVPMQTKEPSTPSEELMDTANWVTFRNLFPAHVSDRASPIPLLHWDDLPEVWTIMTRKEALCPRKHDCLKSHPSLGERMRAILLDWLIEVCEVYRLHRESFYLAADFVDRYLAAKENVPKTKLQLIGITSLFVAAKLEEIYPPKLHEFAYVTDGACTDDQILDQELIMLMTLNWDLTPITVNTWLNAFMQICNAEEIANRKTNFHFPSYSSTEFVQVAQLLDVCTLDIGSMDFDYSILAASALYHVTNEEVTLSVTGLKWDDIAACVQWMSTFAMTIREVGVAQLKNFKNIYAGDAHNIQTHCSSLELLDKSHEKQRLLREASCCSPVQVPGVLTPPQSDKKSKKGVL
What is the function of this protein?
Essential for the control of the cell cycle at the G1/S (start) transition.
What are the official names of this protein?
G1/S-specific cyclin-E.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin E subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYFB_THIDA
Sequence: MQFSEAWLRKLVNPALDTTELAHALTMAGLEVEALTAAAPPFNDVVVAEILSAQKHPDADRLRVCQVDIGEAAPATIVCGAPNAAAGLKVPCARPGAKLPGIEIKVAKVRGVESFGMLCSTKELGLEGAADGLMVLPDDAPVGEDLRGWLNLDDTLVTLKLTPNRADCLSLVGIAREVGAITGAEVRIPQASPVAPRIADTVEVTVAASDACSRYLGRVVRGIDAQATTPRWMAERLERGGIRPLLAPIDVTNYVLLELGQPMHAFALSRLSGGIEVRLARAGETLALLSGQTVELSPDMLVIADASGPVALAGIMGGQATSVERATVDVFLEAAFFAPAAIAGRARRLGLSTDSAHRFERGVDFGAIHAAMERATQLLLDICGGQPGPISEVTGSLPRREPIELRLSRLRRVAGVELGADQVIRDLAALGCVVEQADERLVVTPPSFRFDLAIEEDLIEEAVRLFGYDRIPARPPAAPSRMLAQDETRIADDALRQKMVDLDYQEVITYSFVDPAGEQALDPDVRLLTLANPIASQLSVMRTTLWGGLIETLRHNLNRQQERVRIFELGRVYASLAEQPRKLGGLAYGEALPEQWGVPGRRVDFFDVKGDLERLFGQPLDAGRGEHPALHPGQSAALWVDGHRGGWIGALHPRLVQAFDLAAAPVLFELDSEILARRALPRHAGLSRFPQVRRDLAFVLDAGLAAGDLLAALREAAPASIRAIEVFDDYRGKGVDQNQKSLAIRVVMQDTERTLTDRDVDEAVQKLVDAAARRCSATLRA
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFS1_SCHPO
Sequence: MWFLRETIFGELVEYFSGGTRQVDVEKLGVCTDNSNVELSSCPDSSFDDEKTNQVNSEGLIIVTWDGEDDPENPKNWPLWAKLVVTFDVCFLTFAVYMGSAIFTPGIQEIRETMHVGTVPVILGLTLFVEGYAVGPLIFSPLSEVPQIGRQKIYVLSLIVFICLQIPTALGSSLGVLLPMRFLAGVFGSPALSTGGASLADIWQPWLYPYFMCFWSLGAVGGPVLGPLLGAAMVVAKSWRWQFWLLMMISALVLVIITFFMPETSEWHLLYKRAKRLRELTGNPNYKTEAEIASSQLSKGQFAKQILVRPIILCVSEPIVLSLTIYIGLVYSILYLWFEAFPILFTTVYHFTTIENGLVYMGILVGSVLTVAFYFIYLRKVMIPKFVENKGKFPAEEILIISFPAAFFIPISLFWFGWTGRESVHWIVPIVGTLFYASGSFLLFQSMFQYLAAAYPKYVASVFAGNALFRSSMAAASPLYARAMFNNTGPSYAPVGWGSTILGVISCIMIPIPFLIYKWGLKLRSRSKYAT
What are the official names of this protein?
Transporter mfs1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Protein: IL4_SHEEP
Sequence: MGLTSQLIPALVCLLVCTSHFVHGHKCDITLEEIIKTLNILTSRKNSCMELPVADVFAAPKNATEKETFCRAGIELRRIYRSHMCLNKFLGGLDRNLSSLASKTCSVNEAKTSTSTLRDLLERLKTIMREKYSKC
What is the function of this protein?
Participates in at least several B-cell activation processes as well as of other cell types.  It is a costimulator of DNA-synthesis.  It induces the expression of class II MHC molecules on resting B-cells.  It enhances both secretion and cell surface expression of IgE and IgG1.  It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.  Positively regulates IL31RA expression in macrophages.  Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
What are the official names of this protein?
Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_CLOK5
Sequence: MGQKVHPHGLRVGIIKEWDAKWYADKKNFADNLVEDNKIRKFVKKKGAIAGISKIQIERAAKRIKLNIFTAKPGMIIGKGGQGIEALKTELKKIVPDKVILINIVEVKVAEADAQLMAENIALQLEKRISFRRAMKQTIQRAMKSGIKGVKTTCSGRLGGAEIARSESYHEGTIPLQTLRADIDYGFAEADTTYGKIGVKVWVYKGEVLPVKKPVENKEEAKA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: COX20_MOUSE
Sequence: MAAAPEPHETEKKPFKLLGILDVENTPCARESILYGSLGSIVTGLGHFLVTSRIRRSCDVGVGGFILVTLGCWFHCRYNFAKQRIQERIAREGIKNKILYESTHLDPERKMKTNNSS
What is the function of this protein?
Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX20, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX20 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.