PharMolix/UniProtQA huggingface dataset:
Protein: OBG_STAES
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKAKKGENGQSSNMHGRNAEDLVLKVPPGTIIKSVESEEVLADLVEDGQRAIVARGGRGGRGNSRFATPRNPAPDFSENGEPGEELEVTLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDHRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGRNPLDDYKIINQELINYKQRLEDRPQIIVANKMDLPDSQGNLSHFKEQLDNDVTVVPVSTITRDNIDQLLYQIADKLEEVKDVDFSVEEDENLGVNRVLYKHTPSADKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCSNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_CALS8
Sequence: MKTYLAKPNEVPKKWYVIDATGKPLGRLAAKIAVILRGKHKPQFTPNVDTGDYVIVVNAEKVVLTGKKLDKDGYRYHTKYPGGLKFIPYRRLLEKHPEKAIEIAVRGMLPKNRLRDRFMRKLKVYRGPNHPHAAQKPEVLEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GRW10_SOLLC
Sequence: GGGGRYPGGGGGGRGGGRYSGGGGRGGGGGRGGRGGGGRKCCS
What is the function of this protein?
Responsible for plasticity of the cell wall (Potential).  Might play a role in wound healing and plant disease resistance.
What are the official names of this protein?
Glycine-rich cell wall structural protein, Clone W10-1.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: THIG_METS4
Sequence: MTTPTPLAPDGDDPLVIAGTPLRSRLLIGTAGYPTQAIMAEAVRASGAEIATVSIRRVSLRGHGSDTVSLLAGHRFLPNTAGCETARDAVMTAELAREALGTAWIKVEVIGDRETLYPDVAETLEATRQLVDAGFVVLPYCNDDPVVCARLADLGAAAVMPMGSLIGSGMGVANPANLELICRRSPVPVIVDAGIGTASDAVIAMELGAAAVLLNTAVAKADDPVRMARAMRHAVEAGRLAHGAGRIPRRARAEPSSPQLGLVGS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_BURVG
Sequence: MRDETPEQPAPLRFGYTTGSCATATSLAAARLLLGGRADDAVEIVLPKGQRVMMRLEFCRTTAAGAEAGTIKDAGDDPDVTHGALVFARVALSAAPGVRFHAGPGVGTVTRAGLTLPIGEPAINPVPRQMMTTHLDALAAEHGYTGGFDVTIGVEGGEALALKTMNPRLGIVGGLSILGTTGIVRPFSCAAYIASIHQGIDVARANGIAHIAACTGNASEDAMRAHYGLPDIALIEMGDFAGAVLKHLRRAPLARVSMCGGFGKLSKLAAGHLDLHSRHSSIDLPLLAQWAADAGASDALQAAMRAANTSQEALKLALADGVPLGDIVCAHALRVARDIVPASVAVEMFAIDRQGRFVGSAR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: PANB_CAUVC
Sequence: MSAHREETVRRLAAPDIAARKGGVPIVCLTAYTAPVAAALDDACDVLLVGDSVGMVVHGLPNTVGVTMEMMILHGQAVMRGSKKAMVVVDMPFGSYEASHEEAYANAVRIMKETGAQAVKVESGPTVPETIAYLTRRGVPVMGHVGLRPQAVLLEGGFKAKGKDDAGRAKVLEEARLTAEAGAFAIVVEGVAESLAREVTESVSVPTIGIGASAGCDGQVLVVDDMLGLFDWTPKFVRRYADLKGEIERAAAQYASDVRDRSFPGPAETYYAKKP
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRA13_CAEBR
Sequence: MAIVSSENRTCADEKLLALYQSWSYIASIVFNCLVPTISTYFLGRAIFQLCNQATIQYSTRILLIATILFAACHQVSYFAFKIDLLHTMFFKLDQPCFLQRSSYDCRFISIAQTTGVVGMALTGLAMSTDRALALTFPADYHKLKSVPRVVLSVFVFIVSFSTWFLLTMNDPLTGYLNHCGFYPSYSVANFQLMLDVILYLAIFNLIWDVILFYYARQQILWRRSYQFQKRYEARISLNCTQAVFVISICQCISNGANSGLMRLLMMIGTSITSVTYSSLLSLFYTAPYSCILLPILMMRISEYIREQRTIGILSLRSEKPGLEEHHQRMRAAWS
What is the function of this protein?
Chemosensory receptor that negatively regulates RAS/MAPK signaling during vulva induction and the negative regulation of olfaction of volitile attractants.  Required for the suppression of vulval induction in response to food starvation.  Signaling acts through the GPA-5 G-alpha protein subunit (By similarity).
What are the official names of this protein?
Serpentine receptor class alpha-13, Protein sra-13.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PP116_ARATH
Sequence: MLSESLFKSLGHLASHGHLHDAFKTFSLLRLQSSSAVSDDLVLHSAASLLSACVDVRAFLAGVQVHAHCISSGVEYHSVLVPKLVTFYSAFNLHNEAQSIIENSDILHPLPWNVLIASYAKNELFEEVIAAYKRMVSKGIRPDAFTYPSVLKACGETLDVAFGRVVHGSIEVSSYKSSLYVCNALISMYKRFRNMGIARRLFDRMFERDAVSWNAVINCYASEGMWSEAFELFDKMWFSGVEVSVITWNIISGGCLQTGNYVGALGLISRMRNFPTSLDPVAMIIGLKACSLIGAIRLGKEIHGLAIHSSYDGIDNVRNTLITMYSKCKDLRHALIVFRQTEENSLCTWNSIISGYAQLNKSEEASHLLREMLVAGFQPNSITLASILPLCARIANLQHGKEFHCYILRRKCFKDYTMLWNSLVDVYAKSGKIVAAKQVSDLMSKRDEVTYTSLIDGYGNQGEGGVALALFKEMTRSGIKPDHVTVVAVLSACSHSKLVHEGERLFMKMQCEYGIRPCLQHFSCMVDLYGRAGFLAKAKDIIHNMPYKPSGATWATLLNACHIHGNTQIGKWAAEKLLEMKPENPGYYVLIANMYAAAGSWSKLAEVRTIMRDLGVKKDPGCAWIDTDSGFSLFSVGDTSSPEACNTYPLLDGLNQLMKDNAGYAINKVQSSDEELLQEMG
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g71490.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: SYE_LACDE
Sequence: MANKKIRVRYAPSPTGHLHIGNARTALFNYLFARHNKGTLVLRIEDADTERNVEGGAESQIENLHWLGIDWDEGPDIGGDYGPYKQSERKDIYQKYIDQLLEEGKAYYSFKTEEELEAQREEQRAMGIAPHYVYEYEGMTTDEIKQAQAEARAKGLKPVVRIHIPEGVTYEWDDIVKGHLSFESDTIGGDFVIQKRDGMPTYNFAVVIDDHLMEISHVLRGDDHISNTPKQLCVYEALGWEAPVFGHMTLIINSATGKKLSKRDESVLQFIEQYRELVSCQKPCSTSSSLLGWSPVGESEIFSKREFIKQFDPARLSKSPAAFDQKKLDWVNNQYMKTADRDELLDLALHNLQEAGLVEANPAPGKMEWVRQLVNMYANQMSYTKQIVDLSKIFFTEAKYLTDEEVEEIKKDEARPAIEEFKKQLDKLDNFTAKKIMGAIMATRRETGIKGRKLFMPIRIATTRSMVGPGIGEAMELMGKDTVMKHLDLTLKQLSEAGIE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_BUCAI
Sequence: MTSTKDKIEKLRKILLKYEYFYHTLNQSIISDAEYDYLFRQLYELELKNKELIPSDSPTQKVGSHILQKFKKIKHFSPMLSLENTFDVNGYLNFKKRIKKSIHNNEPLSFCCELKLDGVAISIIYEEGIFVRAATRGDGFEGENITSNARMIDSIPLKLKGIDIPKRLEIRGEVFMLKSNFIKLNKKYKLNQNKYFSNPRNAAAGSLRHIDPNITAERKLIFSCHGCDFFVKTNKELTTHYQRLMKCLSWGIPVNKEIVICSSDIEIIQFYKKIAQKRNFLDFDIDGIVIKVNSLELQKKIGSTTKSPRWAIAFKFSPKERITTLNDVKFQVGRTGVITPVAYFNPVYISGVMISKASLHNKNEIERLNLHFNDTITICRSGDVIPRLLNVIEIRRCDNAKKIIFPSFCPVCNTELLENIEEKLIRCHSGLTCDAQKKQALYHFFSKKSLYVVGLGPKIINELVEKGLVKNPIDFFYLKDIDLIQLKNVGKRKSIKIINSIKKCKKTTLKCFIYALGIPGVGEVVAGKIANYFIKLDKLMNSNILELNCISGVGKIISNNIFNYFSTISNREMVVKLIKQAGIFLNDQEIHKINSEKTYFFNKKIVLTGVFKSFSRIELKTILLSLGAKISNNISRKTDFLIYGNNFGSKFFRAKDLDVKIINQEELNSLIRIKE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: VAB3_CAEEL
Sequence: MSDAGHTGVNQLGGVFVNGRPLPDATRQRIVDLAHKGCRPCDISRLLQVSNGCVSKILCRYYESGTIRPRAIGGSKPRVATSDVVEKIEDYKRDQPSIFAWEIRDKLLADNICNNETIPSVSSINRVLRNLAAKKEQVTMQTELYDRIRIVDNFPYNSSWYGQWPIPMNGAVGLNPFVPAPLIEPKTEGEFEKDEDQKPPTEPEDDAAARMRLKRKLQRNRTSFTQVQIESLEKEFERTHYPDVFARERLAQKIQLPEARIQVWFSNRRAKWRREEKMRNKRSSGTMDSSLSNGTPTPTPGSVTGSNMTNPIGSPASTPNRFPSNNSANLPTTNFVPQTSQMYAGLSQPAMDPYSFGIANGFSMAPYPQVTDFQPHHMFQGRSPYDFPYPRMPTNGHGFQQSMSPATTAVGDIPTLSSGMSLPVSAVLNSIDPSLTHSQMHELSDLTQEHYWRPQ
What is the function of this protein?
Transcription factor that acts within the male-specific genital sensilla (simple sense organs) known as rays to determine their identity (PubMed:7659160, PubMed:1782863, PubMed:15579687).  Promotes BAG sensory neuron fate in a cell-autonomous manner (PubMed:30890567).  Required for function of chemosensory BAG neurons (PubMed:30890567).
What are the official names of this protein?
Paired box protein 6 homolog, Homeobox and paired domain-containing protein vab-3, Protein male abnormal 18, Variable abnormal morphology protein 3.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus. SUBCELLULAR LOCATION: [Isoform b]: Nucleus. Cytoplasm. Note=Nuclear localization is temporally and spatially regulated in two sets of neuronal sublineages.
Protein: SYM_PSEE4
Sequence: MSEPRQILVTSALPYANGSIHLGHMLEYIQTDMWVRFQKLRGNQCVYVCADDAHGSAIMLRAEKEGITPEQLIANVQAEHSSDFADFLVDFDNFHSTHSEENRELSGLIYTRLRDAGHIATRSVTQYFDPEKGMFLADRFIKGTCPKCAAEDQYGDNCEKCGATYAPTELKNPKSAISGATPVLRDSQHFFFKLPDFQAMLQQWTRSGTLQDAVANKLAEWLDSGLQEWDISRDAPYFGFEIPGEPGKYFYVWLDAPIGYMASFKNLCARRPELDFDAFWSEGSKAELYHFIGKDIVNFHALFWPAMLEGSGFRKPTAVNVHGYLTVNGAKMSKSRGTFIKARTYLDHLQPEYLRYYYAAKLGRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNDGVMVAGDAAPDLTEAFLAAAPSIAEAYESRDFGRAMREIMALADRANAWIADKAPWSLAKQEGKQEEVQAICAQGINLFRQLVIFLKPVLPLLAADAEAFLNVAPLTWNDHLSRLENHKLNPFKALMSRIEPAKVEAMIAASKEDLLAAEAKAPAGNGELTKDPLSAEIEFDTFAAVDLRVALIVKAEAVPGADKLLQLTLDIGDERRNVFSGIKSAYPDPSKLEGRLTMMVANLKPRKMRFGVSEGMVMAAGPGGEEIYLLSPDSGAKPGQRIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_LEGPL
Sequence: MTKELCMRCYISGRVQGVWFRASAKNLAEQLMISGWARNLADGRVEVFACGKEDKLEEFYTWLQKGPLNARVDVCTRENLPWEDYITFDVL
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: BGL43_ARATH
Sequence: MFLFLLLLSASRSGEESPSGDAVPLATGGLNRKSFPEGFLFGTATSAYQVEGETHQDGRGPSIWDAFVKIPGKIANNATAEITVDQYHRYKEDVDLMQNLNIDAYRFSISWSRIFPEGSGKINSNGVAYYNRLIDYLIEKGITPYANLYHYDLPLALEQKYQGLLSKQGRFCGLRRVLFQTFGDRVKNWMTFNEPRVVAALGYDNGIFAPGRCSEAFGNCTDGNSATEPYIVAHHLILAHAAAVQRYRQNYQEKQKGRVGILLDFVWFEPLTSSQADNDAAQRARDFHVGWFIHPIVYGEYPNTLQNIVKERLPKFTEEEVKMVKGSIDFVGINQYTTYFMSDPKISTTPKDLGYQQDWNVTFNFAKNGTPIGPRAHSEWLYNVPWGMYKALMYIEERYGNPTMILSENGMDDPGNITLTQGLNDTTRVKYYRDYLVQLKKAVDDGANLTGYFAWSLLDNFEWLSGYTSRFGIVYVDYKDLKRYPKMSALWFKQLLKRDQK
What are the official names of this protein?
Beta-glucosidase 43, AtBGLU43.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: CYB_URILO
Sequence: MAPNLRKSHPLLKLINNSLIDLPTPSNISAWWNFGSLLGICLLTQILTGLLLATHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLNKETWNTGVILLLALMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLAFIHLTFLHESGSNNPLGILSNCDKIPFHPYFSLKDILGFIIMFLPLTTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLTPLLHKSKQRAMTFRPLSQLLFWTLVANLLILTWVGSQPVEHPFIIIGQLASLAYFTILLLLFPIVGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GPX4_SAPAP
Sequence: MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCAGSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPHYF
What is the function of this protein?
Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins (By similarity).  Can also reduce fatty acid hydroperoxide, cholesterol hydroperoxide and thymine hydroperoxide (By similarity).  Plays a key role in protecting cells from oxidative damage by preventing membrane lipid peroxidation (By similarity).  Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species (By similarity).  The presence of selenocysteine (Sec) versus Cys at the active site is essential for life: it provides resistance to overoxidation and prevents cells against ferroptosis (By similarity).  The presence of Sec at the active site is also essential for the survival of a specific type of parvalbumin-positive interneurons, thereby preventing against fatal epileptic seizures (By similarity).  May be required to protect cells from the toxicity of ingested lipid hydroperoxides (By similarity).  Required for normal sperm development and male fertility (By similarity).  Essential for maturation and survival of photoreceptor cells (By similarity).  Plays a role in a primary T-cell response to viral and parasitic infection by protecting T-cells from ferroptosis and by supporting T-cell expansion (By similarity).  Plays a role of glutathione peroxidase in platelets in the arachidonic acid metabolism (By similarity).  Reduces hydroperoxy ester lipids formed by a 15-lipoxygenase that may play a role as down-regulator of the cellular 15-lipoxygenase pathway (By similarity).
What are the official names of this protein?
Phospholipid hydroperoxide glutathione peroxidase, PHGPx, Glutathione peroxidase 4, GPx-4, GSHPx-4.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm.
Protein: RL28_SYNFM
Sequence: MSRKCEFCGKEPHVGNNVSHANNKTKRLWYPNLQTVRHMDKSGAVRRVKACTRCIRTGLVVKPA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: S26A8_MACFA
Sequence: MLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKISPLNNGHLVMGSFLKDEFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTCIFGIMISFHAGPISFFYDIINYCVALPKANSTSILLFLTVVVALRINKCIRISFNQYPIEFPMELFLIIGFTVIGNKITMATETSQTLIDMIPYSFLFPVTPDFSVLPKIILQAISLSLVSSFLLVFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAVARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYALPNAVLAGIILSNVVPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITSVRSHRAKILLLGQIPNTNIYRSVNDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKEVGMVRVPLKEEEIFSLFNSSDTSLQGEKICRCFCNCDDLEPLPRILYTERFENKLDPDASSVNLIHCSHFESVNTSQTASEDQVPYTVSSMSQKNQGQQYEEVEKVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFSMVHYVDSQGLVVLRQICNAFRNANILILIAGCHSSLFCTGITLPDHITKCQQLSLNSLSRLPSFHLQHIF
What is the function of this protein?
Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport.  May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis.  May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells.  A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility (By similarity).
What are the official names of this protein?
Testis anion transporter 1, Anion exchange transporter, Solute carrier family 26 member 8.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Located at the annulus ring structure within the sperm cell.
Protein: NUSB_RHOPA
Sequence: MAEINKPAFKKPDLKKMTPKGERKANRRGAARLAAVQALYQMDIGGAGINETFAEFESFWIGNEVEGEQYLPAEAAFFRDIVAGVVREQKQIDPLIDDLLARGWPLARIDAILRAVMRAGAYELEHRKDIPARVVVSEYVDVAHAFVEKDETGMVNAVLDQIARRFREDEFTRS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CMOB_SHEPW
Sequence: MISFSSFYKQISDSSLQHWLETLPAILGEWQREHKHGSLPKWEKVLNKLHYPQPDTIDFTTSVTIGSGEQLSAGEREKLENLLAIFKPWRKGPYSIHGVEIDTEWRSDWKWERIAPHISPLANRTVLDVGCGSGYHMWRMLGEGAKHVVGIDPSPMFMCQFEAVKRIAGNEHPVHFLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLIQLRDQLRTGGELVLETLVIDGDENTVLVPEDRYGKMNNVWFLPSVKALMLWLKKSDFIDIRCVDVDVTSLAEQRSTHWMPNESLVDYLDPNDVSLTVEGYPAPKRATIIATKNQPNKETK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: SCX12_TITDI
Sequence: IGMVIECKDGYLMEPNGCKRGCLTRPARYCANECSRVKGTDGYCYAWLACYCYNMPNWVKTWDRATNTCGRGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Td12, T-beta* NaTx13.7.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PA2G4_RAT
Sequence: MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVIGVAQGSQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEENGAGD
What is the function of this protein?
May play a role in a ERBB3-regulated signal transduction pathway.  Seems be involved in growth regulation.  Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG).  Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity.  Binds RNA.  Associates with 28S, 18S and 5. 8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA.  May be involved in regulation of intermediate and late steps of rRNA processing.  May be involved in ribosome assembly.  Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site).  Together with PTBP1 is required for the translation initiation on the foot-and-mouth disease virus (FMDV) IRES (By similarity).  Regulates cell proliferation, differentiation, and survival.  Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation.
What are the official names of this protein?
Proliferation-associated protein 2G4.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. Nucleus, nucleolus. Note=Phosphorylation at Ser-361 by PKC/PRKCD regulates its nucleolar localization. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: CYB_POLSX
Sequence: MGSLLGLCLIVQIITGLFLAMHYVSDISSAFSSVAHICRDVNYGWLIRNFHANGASLFFICIYLHIARGLYYGSYLYMETWNIGVILLLLTMMTAFVGYV
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EAA1_RAT
Sequence: MTKSNGEEPRMGSRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVSAVIVGTILGFALRPYKMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQANETLLGAVINNVSEAMETLTRIREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKILEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNEPEKPVADSETKM
What is the function of this protein?
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:1279699, PubMed:8387171).  Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (By similarity).  Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).
What are the official names of this protein?
Excitatory amino acid transporter 1, Glial glutamate transporter, Sodium-dependent glutamate/aspartate transporter 1, GLAST, GLAST-1, Solute carrier family 1 member 3.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRP2_PYRAP
Sequence: APASGFFGMR
What are the official names of this protein?
Tachykinin-related peptide 2, TKRP-2.
What are the subcellular locations of this protein?
Secreted.