PharMolix/UniProtQA huggingface dataset:
Protein: SECB_SHIFL
Sequence: MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_VIBVU
Sequence: MALNLQDKKAIVAEVNEAAAGALSAVVADSRGVSVDAMTTLRKQAREAGVYMKVVRNTLARRAVEGTQYECLTDTFTGPSLIAFSNEHPGAAARLFKDFAKENKKFEIKAAAFEGALTDAEVLATLPTYDEAIARLMMCLKEASAGKLVRTIAAIRDQKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MDHC_MESCR
Sequence: MAVEPLRVLVTGAAGQIGYALVPMIARGIMLGANQPVILHMLDIPPAAEALNGVKMELVDAAFPLLKGVVATTDAAEACKGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKAQASALEQHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLNVQVSDVKNVIIWGNHSSTQYPDVNHATVKTQGVDKPVRELVADDAWLNGEFITTVQQRGAAIIKARKLSSALSAASSACDHIHDWVLGTPEGTWVSMGVYSDGSYNVPAGIIYSFPVTCKNGEWTIVQGLPIDDDSRKKMDATAAELVEEKTLAYSCLT
What are the official names of this protein?
Malate dehydrogenase, cytoplasmic.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_NEIM0
Sequence: MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFEPMKTLTAIKNVTINEPQFQGHFPDLPVMPGVLIIEAMAQACGTLAILSEGGRKENEFFFFAGIDEARFKRQVIPGDQLVFEVELLTSRRGIGKFNAVAKVDGQVAVEAVIMCAKRVV
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_PYRIL
Sequence: MDIEERISLVLKYPTEEVITVEELRELFQSGYKLNHYIGFEISGFIHIGTGVVSMSKVVDLQKAGVKTQVFLADIHSWLNNKLGGDLDIIRKVAVTYYVETFKKIIEVLGGDPDATRFILGSELYHHNDEYWLLLMDITRHLTLSQVRHSLTILGRKMGESIPLAYLVYPPLQVADVFALEAHIPHGGIDQRRAHILARQVADKIRFYPLKVDGKRIKPVALHHKLLPALNITSKPSSREELSEMKMSKSIPQSAIFVHDSPDEIRQKIAKAYCPPRDTEYNPVLELLRISAFREKRKTPLVIKRPAQYGGDLEVWSYEELEALYRDGRVHPADLKTATSEALITLLEPVYRYFQGPGAKLLEEMKNITITR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IORA_ARCFU
Sequence: MLNDVVRDAEGEKVFLLGNEAIARGAIEAGIDVFAAYPGTPSSEIADTLSDACRLLRGKMDFYMEYSANEKVAFEVAVGASLAGKRAMATMKHVGVNVAADPLFSFAYVGARGGFVLVTADDPSMHSSQNEQDNRWYGKAAKLPVVEPSSVQEAKDYAKLCFDLSEKFGLPMILRSYTRLSHASGVVELGKIPEKEFSRVEWERHPETDVVLPAHARKLKPILLEKLEKIERYFNSSEMNWVDEGDGDVGIIACGLSYAYTKEALENLNLNLPVLKLSSMHPLPERLIENFVSQMKKVIVVEEVDPFVELHVRAMGLAEVYGKMNGYMPMNYEYNVGRVETGIAKALGIKPSRDYEGIVAESQKLAAKAPPRPPVLCPGCPHSASFYAIRRVVDELGDAALPSDIGCYTLGINKPLEGVDITICMGASVGVSNGLAHVLNNKIIATIGDSTFIHAGIPPLINAVYNHADFVLVILDNSTTGMTGHQPHPGTGFRGCGEAGKAVRIEDIVRGCGVEFVEVVNPYNVRKMVDVLRRALNHDGVAVVIARQPCAILWSRARRREGKIVTYKVTEDCTLCMECVNTFACPALIFDGEKVSIDQSLCVGCAVCAKICPNRAIKPAKSN
What is the function of this protein?
Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
What are the official names of this protein?
Indolepyruvate oxidoreductase subunit IorA, IOR, Indolepyruvate ferredoxin oxidoreductase subunit alpha.
Protein: YA22_SCHPO
Sequence: MKSTKTQPSPEREREPSFFQKLFGNLCSCFQDASIDEKPTYTPAKPVKKAPSVVQPRRVSRTLRSSESVHTNHGPERVFESPTPARTSISLESAISPNGTTNEQDIAQQGDMIDSHVHFGEQPTEPIDFADPPLPEVKRYGEGNWLLPPIAKEDEGKKCLILDLDETLVHSSFKYIEPADFVVSIEIDGLQHDVRVVKRPGVDEFLKKMGDMFEIVVFTASLAKYADPVLDMLDHSHVIRHRLFREACCNYEGNFVKDLSQLGRNLEDSIIIDNSPSSYIFHPSHAVPISSWFNDMHDMELIDLIPFLEHLARVPDVSTVLNLQL
What are the official names of this protein?
Uncharacterized protein C2F7.02c.
Protein: FOLD_BURO1
Sequence: MTALLIDGNALSKTLRAQAAERAAALTARGHQPGLAVILVGANPASEVYVRNKIKACEDNGFFSLKDAYPATLSEADLLARIDELNRDPKIHGILVQLPLPAHIDSHKVIEAIAPEKDVDGFHVANAGALMTGKPLFRPCTPYGVMKMFEAHGIALQGANAVVIGRSNIVGKPMAMMLLDAGATVTICHSKTRDLAAHTREADIVVAAVGKRNILTADMVKPGATVIDVGMNRDDAGKLCGDVDFAGAKEVAGYITPVPGGVGPMTITMLLINTIESAERAAAAA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL10_MYCLB
Sequence: MARADKATAVANIAEQFKAATAALITEYRGLTVANLAELRRSLTGSASYAVAKNTLIKRAASEVGIEGLDELFAGPTAIAFVTGEPVDAAKAIKTFAKEHKALVIKGGYMDGHPMTVAEVERIADLESREVLLAKLAGAMKGTFAKAIGLFNAPTSQMARLTAALQEKKAFEPASAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: AAKB1_RAT
Sequence: MGNTSSERAALERQAGHKTPRRDSSGGTKDGDRPKILMDSPEDADIFHTEEMKAPEKEEFLAWQHDLEVNEKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSQNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSSSPPGPYHQEPYISKPEERFKAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI
What is the function of this protein?
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.  In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.  AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.  Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.  Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
What are the official names of this protein?
5'-AMP-activated protein kinase subunit beta-1, AMPK subunit beta-1, AMPKb, 5'-AMP-activated protein kinase 40 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the 5'-AMP-activated protein kinase beta subunit family.
Protein: STP_SHV2C
Sequence: MASEPNLRYPIEETGDRGPPGPPGPPGPQGPPGPQGPPGPQGPPGPPGPPGPPGPPGPPGPPGPPGPPGLPGLFVTNLLLGIIVLLLLIIVALLLVSKLVVN
What is the function of this protein?
Acts synergistically with Tip to stimulate NF-kappa-B activity and interleukin-2 gene expression by binding to host TRAF proteins.  Activation of NF-kappa-B protects lymphocytes from apoptosis, thereby facilitating viral induced cell transformation.
What are the official names of this protein?
Saimiri transformation-associated protein, Collagen-like protein, stpC.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: Y2303_STRP2
Sequence: MNKKFLKCGTLFLISCSILGSTIPAVTVFSDEVTITYNSENNSEKNELYNQLSAEKKGQFDELVSNLNLSEQEQLDLLQQYKEEHPRRAKRGIKSAIIKKVARFLAAKVGQKSVVEITDYLFEWQDNLEAGAENYLVQYGWDRNIAHWTIKTVSFIFL
What are the official names of this protein?
Uncharacterized protein SPD_2303.
Protein: PETN_PROMS
Sequence: MIFQIGWAALAAIFTFSIAMVVWGRNGDGSIDI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS5_PSEA7
Sequence: MANNEQKRDEGYIEKLVQVNRVAKTVKGGRIFAFTALTVVGDGKGRVGFGRGKAREVPAAIQKAMEAARRNMIQVDLNGTTLQYPTKSAHGASKVYMQPASEGTGIIAGGAMRAVLEVAGVQNVLAKCYGSTNPVNVVYATFKGLKNMQAPEAVAAKRGKSVEEIL
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SSG1_ORYSI
Sequence: MSALTTSQLATSATGFGIADRSAPSSLLRHGFQGLKPRSPAGGDATSLSVTTSARATPKQQRSVQRGSRRFPSVVVYATGAGMNVVFVGAEMAPWSKTGGLGDVLGGLPPAMAANGHRVMVISPRYDQYKDAWDTSVVAEIKVADRYERVRFFHCYKRGVDRVFIDHPSFLEKVWGKTGEKIYGPDTGVDYKDNQMRFSLLCQAALEAPRILNLNNNPYFKGTYGEDVVFVCNDWHTGPLASYLKNNYQPNGIYRNAKVAFCIHNISYQGRFAFEDYPELNLSERFRSSFDFIDGYDTPVEGRKINWMKAGILEADRVLTVSPYYAEELISGIARGCELDNIMRLTGITGIVNGMDVSEWDPSKDKYITAKYDATTAIEAKALNKEALQAEAGLPVDRKIPLIAFIGRLEEQKGPDVMAAAIPELMQEDVQIVLLGTGKKKFEKLLKSMEEKYPGKVRAVVKFNAPLAHLIMAGADVLAVPSRFEPCGLIQLQGMRYGTPCACASTGGLVDTVIEGKTGFHMGRLSVDCKVVEPSDVKKVAATLKRAIKVVGTPAYEEMVRNCMNQDLSWKGPAKNWENVLLGLGVAGSAPGIEGDEIAPLAKENVAAP
What is the function of this protein?
Required for the synthesis of amylose in endosperm.
What are the official names of this protein?
Granule-bound starch synthase 1, chloroplastic/amyloplastic, Granule-bound starch synthase I, GBSS-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Amyloplast or chloroplast, granule-bound.
Protein: KEFG_ECO81
Sequence: MMSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSAQELASHARAYGDWLANPLSPGGC
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IDD_HUMAN
Sequence: MVPKADSGAFLLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGKEAVDPRQGRARGGDPSHFHAVNVAQPVRFSSFLGKCPTGWHHYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPERSFGWKDQRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCAQLQCFHFPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGFYFTPKGDDPCLSCTCHGGEPEMCVAALCERPQGCQQYRKDPKECCKFMCLDPDGNSLFDSMASGMRLVVSCISSFLILSLLLFMVHRLRQRRRERIESLIGANLHHFNLGRRIPGFDYGPDGFGTGLTPLHLSDDGEGGTFHFHDPPPPYTAYKYPDIGQPDDPPPPYEASIHPDSVFYDPADDDAFEPVEVSLPAPGDGGSEGALLRRLEQPLPTAGASLADLEDSADSSSALLVPPDPAQSGSTPAAEALPGGGRHSRSSLNTVV
What is the function of this protein?
Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.
What are the official names of this protein?
Integral membrane protein DGCR2/IDD.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PSAB_MARPO
Sequence: MASRFPKFSQGLSQDPTTRRIWFGIATAHDFESHDDMTEERLYQKIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWGQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGASGPVNIAYSGVYQWWYTIGLRTNQDLYNGALFLVILSSISLIAGWLHLQPKWKPKVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGEHVRWDNFLTKLPHPEGLGPFFAGQWNIYAQNVDSSNHAFGTSQGAGTAILTFIGGFHPQTQSLWLTDIAHHHLAIAVVFIIAGHMYRTNFGIGHSIKEILETHTPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPPYAFLAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNKDNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKALYGFDVLLSSTNNPAFNAGQSIWLPGWLDAINNNSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKEFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNAAQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLVRWKDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DEOD_HAEIG
Sequence: MTPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRNMLGFTGTYKGRKISIMGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGTVRMDVKVRDVIIGLGACTDSKVNRIRFKDNDFAAIADFDMAQAAVQAAKAKGKAVRVGNLFSADLFYTPDVEMFDVMEKYGILGVEMEAAGIYGVAAEYGAKALTICTVSDHIRTHEQTTAEERQLTFNDMIEIALDSVLIGDAQ
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: TSIV3_VIBCH
Sequence: MNNLLSAYVTMLLILLSISGGAIASENCNDTSGVHQKILVCIQNEIAKSETQIRNNISSKSIDYGFPDDFYSKQRLAIHEKCMLYINVGGQRGELLMNQCELSMLQGLDIYIQQYIEDVDNS
What is the function of this protein?
Immunity protein that plays a role in preventing early activation of toxin VgrG3.
What are the official names of this protein?
Antitoxin protein TsiV3.
Protein: CFI1_MEDSA
Sequence: MAASITAITVENLEYPAVVTSPVTGKSYFLGGAGERGLTIEGNFIKFTAIGVYLEDIAVASLAAKWKGKSSEELLETLDFYRDIISGPFEKLIRGSKIRELSGPEYSRKVMENCVAHLKSVGTYGDAEAEAMQKFAEAFKPVNFPPGASVFYRQSPDGILGLSFSPDTSIPEKEAALIENKAVSSAVLETMIGEHAVSPDLKRCLAARLPALLNEGAFKIGN
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.
What are the official names of this protein?
Chalcone--flavanone isomerase 1, Chalcone isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: DADA_SALTY
Sequence: MRVVILGSGVVGVTSAWYLSQAGHDVTVIDRESGPAQETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTPFQLKWMWQMLRNCDTRHYMENKGRMVRLAEYSRDCLKTLRAATGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLARMAEQAGVTFRFNTPVEKLLYENDQIYGVKCADEIIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIVEPDGAPVSTILDETYKIAITRFDKRIRVGGMAEIVGFNTDLLQPRRETLEMVVRDLFPRGGHIEQATFWTGLRPMTPDGTPVVGRTRYKNLWLNTGHGTLGWTMACGSGQLLSDILSGRTPAIPYDDLSVARYRSDFTPTPPQRLHSAHN
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAPA_STRP4
Sequence: MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDGILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFGGFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLADHPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGDEMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPLVPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUMO2_ARATH
Sequence: MSATPEEDKKPDQGAHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVDFNSIAFLFDGRRLRAEQTPDELEMEDGDEIDAMLHQTGGGAKNGLKLFCF
What is the function of this protein?
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer.  Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process.  Required for the massive protein sumoylation in the nucleus induced by heat shock and controlled by SIZ1.
What are the official names of this protein?
Small ubiquitin-related modifier 2, AtSUMO2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RL23_BACCR
Sequence: MRDPRDIIKRPVITERSMEMMAEKKYTFDVDVKSNKTEVKDALEAIFGVKVEKVNIMNYKPKAKRVGRHAGFTSRRRKAIVKLTADSKEIEIFQGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NUOC_MYCSK
Sequence: MTEANGTTGGGAGDPEVIDVRRGMFGAKGSGDTSGYGRLIRSVALPGGSPRPYGGHFDEVVDALAAALGQDLYDASVERIVVYRDELTLEIARARLPVVAKTLRDDAALRFELCLGVSGVHYPGDAGRELHAAYPLMSITHNRRIRLEVAAPDDDPHIPSLFSVYPTTDWHERETYDFFGIIFDGHPSLTRIEMPDDWVGHPQRKDYPLGGIPVEYHGARIPPPDERRAYN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPC1_DANRE
Sequence: MDLTAVALLVSLVSVSLSAENAGGKARSCTDVRQFYSGKGFTLNGVPQSEISGEHLRICPQGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQALLNAQYRTFDTYFLELLNGSERWLEEAFVAALGELYRLNAGVFRDLYAELHRYYSGASLNLEEALDEFWMKLLERLLKASDPETASLLSDDFLDCASKQTETLRPFGDAPRELKAKLVRAFIAARAFVQGLNAAGEIVRKVSQVPLSPECNRAIMKLVYCPHCRGLGSVKPCINYCKNVMKGCLANQADLDTEWQSLIETMLQVASSFGAEPSMDTVIYSIPVRISEAVLAMQENMEIYTSKVFKACGDRGEEGTPSSISEEPKKKERTVTALEYKPSPKSAARLEVQVTDVYSKLKEMQLYWIQLPSALCSGKTASSTTGDKCWNGITKASYLPEVMGDGLANQINNPEVEIDITKPDRTIRQQIMLLKIMSNRLKNALEGNDVDFQDTSDDFSGSGSGMCADHLCVRGRPPVFGPKTDRPKLYATGPENKRVKGSGNQIQPSFILLIVFFVSLLLRR
What is the function of this protein?
Cell surface proteoglycan that bears heparan sulfate.
What are the official names of this protein?
Glypican-1.
What is the protein family that this protein belongs to?
Belongs to the glypican family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. SUBCELLULAR LOCATION: [Secreted glypican-1]: Secreted, extracellular space.
Protein: DAPH_CLOPS
Sequence: MSYNFTDPYEIARFIKEVKKSTPVKVYLKGNLEGVELGSIECYGNNDFYVLFGESDEVATFLTENKDKIVSFRLENDRRNSAIPMLELLNINARIEPGAIIRDRVSIGDNAVIMMGAVINIGAEIGESTMVDMNAVIGARGKLGKRVHLGAGAVVAGVLEPPSKTPCIIEDDVLIGANAVILEGVKIGKGSVVAAGSVVVEDVPAGVVVAGTPAKIIKSVDEKTKDKTEILDDLRK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: CNBL1_ORYSJ
Sequence: MGCFQSTARRPRPGYEDPVGLASETAFSVSEVEALFELFKSISGSVIDDGLINKEEFQLALFKNKRKENLFANRIFDLFDVKKRGVIDFGDFVRALNVFHPNIPMEEKIDFSFKLYDMDNTGFIERKEVKQMLIALLGESEMRLSDEIIETILDKTFSDADTNQDGRIDRTEWENFVSRNPSLLKIMTLPYLKDITTTFPSFVFNSEVDDLVT
What is the function of this protein?
Acts as a calcium sensor.  CBL proteins interact with CIPK serine-threonine protein kinases.  Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
Calcineurin B-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain membrane; Lipid-anchor. Note=Tonoplast.
Protein: PPIF_HUMAN
Sequence: MLALRCGSRWLGLLSVPRSVPLRLPAARACSKGSGDPSSSSSSGNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357).  Involved in regulation of the mitochondrial permeability transition pore (mPTP) (PubMed:26387735).  It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated (PubMed:26387735).  In cooperation with mitochondrial p53/TP53 is involved in activating oxidative stress-induced necrosis (PubMed:22726440).  Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels (By similarity).  Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis (PubMed:19228691).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase F, mitochondrial, PPIase F, Cyclophilin D, CyP-D, CypD, Cyclophilin F, Mitochondrial cyclophilin, CyP-M, Rotamase F.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.