PharMolix/UniProtQA huggingface dataset:
Protein: ABIG1_LACLC
Sequence: MAFLPRYYPENIEYLKISKENTPLKEWYIPMTCFCDIPLHQMSYHAEGKAQTGYGKFSIALHKKFGINNGIQPVQYLNSNSIPTEELRNAISILLSDNGQIYSDEALISLSNHLFEYMRRIKPLDGSMKKWDKEGKKYVEIKKNFHDEHEWRYIPDFESDELPFLLYRQDDIIAESSSQFYTKSITETKNGLLNFSVSDIRYIFVDSILSREKLISFIKRKQKGKRIPRAEKDILISKILVYDEIKEDW
What is the function of this protein?
Confers resistance to phages by a mechanism of abortive infection.  Seems to act by interfering with phage RNA synthesis.  Does not act at the level of phage DNA synthesis.
What are the official names of this protein?
Abortive phage resistance protein AbiGi.
Protein: NRAM_I85A5
Sequence: MNPNQKIITIGSASLGILILNVILHVVSIIVTVLVLNNNGTGLNCNGTIIREYNETVRVERVIQWYNTNTIEYIERPSNEYYMNNTEPLCEAQGFAPFSKDNGIRIGSRGHVFVIREPFVSCSPSECRTFFLTQGSLLNDKHSNGTVKDRSPYRTLMSVKIGQSPNVYQARFESVAWSATACHDGKKWMTVGVTGPDNQAVAVVNYGGVPVDIINSWAGDILRTQESSCTCIKGDCYWVMTDGPANRQAKYRIFKAKDGRIIGQTDISFNGGHIEECSCYPNEGKVECVCRDNWTGTNRPILVISPDLSYTVGYLCAGIPTDTPRGEDSQFTGSCTSPLGNKGYGVKGFGFRQGTDVWAGRTISRTSRSGFEIIKIRNGWTQNSKDQIRRQVIIDNPNWSGYSGSFTLPVELTKKGCLVPCFWVEMIRGKPEETTIWTSSSSIVMCGVDHKIASWSWHDGAILPFDIDKM
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: PTMCB_STAAR
Sequence: MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWFPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLATLVSFVVAALIMKFTKEPKQDLEAATAQMETTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXR_ALKCK
Sequence: MKQISLLGSTGSIGTQTLDVIRDYPDQFTLSALACGTNLELCRNQIKEFQPKLVSVQRPEDAQTLAGEFGDSIEFLYGEEGLKEVARYSESDIVVTAITGSIGLLPTLSAIKAKKAVAIANKETLVSAGHLVVSAAKENDVPLIPVDSEHSAIFQALNGEPKKAVDRLILTASGGSFRDKSRAELDGVTVEQALAHPNWSMGAKVTIDSATMMNKGLEVIEAKWLFGLDYDQIDVLIHKESIIHSMVEYVDRSVIAQLGTPDMRVPIQYALTYPERFARPKHERLDLAELGKLHFEKMDMERFRCMKLAYEAGRAGGTMTTVLNAANEVAVCRFLQGEITFLEIERIIEEALSAHSPIAHPSLEEIQAVDASIRKQLQA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: THII_ECOBW
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTEQEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNKTWLLWCERGVMSRLQALYLREQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADA17_RAT
Sequence: MRQRLLFLTTLVPFVLAPRPPEEPGSGSHLRLEKLDSLLSDYDILSLSNIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQDFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQSPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSLDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPGVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACADTDNSCKVCCRNLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMDSASVRIIKPFPAPQTPGRLQALQPAAMMPPVSAAPKLDHQRMDTIQEDPSTDSHVDDDGFEKDPFPNSSAAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC
What is the function of this protein?
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form.  Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface.  Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein.  Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT).  Plays a role in the proteolytic processing of ACE2 (By similarity).  Plays a role in hemostasis through shedding of GP1BA, the platelet glycoprotein Ib alpha chain (By similarity).  Mediates the proteolytic cleavage of LAG3, leading to release the secreted form of LAG3 (By similarity).  Mediates the proteolytic cleavage of IL6R, leading to the release of secreted form of IL6R (By similarity).  Mediates the proteolytic cleavage and shedding of FCGR3A upon NK cell stimulation, a mechanism that allows for increased NK cell motility and detachment from opsonized target cells.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, TNF-alpha convertase, TNF-alpha-converting enzyme.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: XNI_ECO27
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFKSLEGIYENLNAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: Y2199_MYCGI
Sequence: MASTDEPAAASGDSTARARQAEAIVNHAEHSISEDAIVAAARERAVDIGAGAVTPAVGALLCVLAKLTGAKAVVEVGTGAGVSGLWLLSGMREDGVLTTIDVEPEHQRIAKQAFSEAGVGPGRTRLISGRAQEVLTRLADESYDLVFIDAAPADQPQFVVEGVRLLRPGGAIVVHRAALGGRAGDASAKDSEVSAVREAARLIAEDERLTPVLIPLGDGLLAAARD
What are the official names of this protein?
Putative O-methyltransferase Mflv_2199.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: MIC25_HUMAN
Sequence: MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAAHKG
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC25, Coiled-coil-helix cristae morphology protein 1, Coiled-coil-helix-coiled-coil-helix domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
Protein: AROE_RHIE6
Sequence: MGDSRETFGPKAFVTGFPIKHSRSPLIHGYWLKTLGLPGSYRAHEVAPEAFADFIASLKDGSSGFAGGNVTIPHKELAFRLADRPDALSQELGASNTLWLEDDLLHATNTDGRGFTANLDERHPGWDRHDTAVIFGAGGASRAIIQAVRDRGFKTIHVVNRTVGRARELADRFGPKVHAHPAGALAEVMKGAGLFINTTSLGMDGEAAPQLDFTPLTADAVVTDIVYVPLKTPLLAQAQEQGFPIVDGLGMLLHQAVPGFEKWFGKRPVVDAALRALIIADMEAH
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ATPF_SYNP1
Sequence: MDAVILMATEEVGHFGLNTNLLETNVINLAIIIGVLVYFGRGLLGKTLGDRQQQIATAIAEAEERQRTAAARLAQEQQKLAQAKEEAARIREAALVRAKAAKEELIAKAQQEIERLKQTASQDTSAATERAIAEIRERITALALAQAEQQLKERLSHDAELQRTLVDRSIALLGGK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: IF2_CLOPS
Sequence: MSKIRVYELAKELRVPSKVLINVLMDEFGVEVKNHMSVIEDEDAALIKELLAGSEANSELVAEYEAELAEEVNNAAKKKKKRKKGSEDDSLEQDVEVIEIGKTITVKELAEKLNKPVNDVIKTLIFTGVMAAINQEIDFETAEKVAEKYEVAVYEKEEENTLEEFEEETDVEEENLAKRPPIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVEVNGETLTFLDTPGHEAFTAMRARGAQITDVVILVVAADDGIMPQTVEAINHCKAANVPMIVAINKMDREGANPDRVKQELTEHGLVVEDWGGDIIAVPVSAKTRENIDTLLEMVLLTSEMQELKADAGRKAKGTVVEAKLDKGRGAVATLLVQNGTLHMGDSIIVGSTYGRIRAMFDDSGKKIKSAGPSIPVEVLGLSEVPAAGDRFTVVKDEKTARNMAEARKEKIRQESFATSHRVSLEDLYSQIKEGSVKELSVIVKADVQGSVEAIKASLEKLSTDDVKVRVIHGAVGAISETDITLAAASNAIVIGFNVRPDNNAVAASERDGVEVKTYRVIYDAIEDIKSAMIGMLDPEYKEVVLGTAEIRATYKISNVGTIAGGYVLTGKLVRNADVRVIREGIVIFESKLASLKRFKDDVKEVNAGYECGFSVEKFNDIKEGDIIEAYTMEAVQRKEL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGS9_MOUSE
Sequence: MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMHNQRVLVTSVPHAMTGGDVLQWITQRLWISNLEAQNLGNFIVKYGYIYPLQDPKNLILKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYDFLNKKINYKWDFVIMQAKEQYRTGKERNKADRYALDCQEKAYWLVHRSPPGMNNVLDYGLDRVTNPNEVKKQTVTAVRKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQETTKRSSTLPFMRRHLRSSPSPVILRQLEEEEKAREAANTVDITQPGQHLAPSPHLAVYTGTCVPPSPSSPFSPSCRSPRKPFASPSRFIRRPSIAICPSPSRVALEGSSGLEPKGEASWSGANSGPSVTENREPSADHSRPQPRAPPKARAALSLGRFLRRGCLASPVFARLSPKCPSVSHGKVQPLGDMGQQLPRLKPKKVANFFQIKMEMPTDSGTCLMDSDDPRAGESGDQTTEKEVICPWESLAEGKAG
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to GNAT1.  Involved in phototransduction; key element in the recovery phase of visual transduction.
What are the official names of this protein?
Regulator of G-protein signaling 9, RGS9.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Peripheral membrane protein. Note=Isoform 1 is targeted to the membrane via its interaction with RGS9BP.
Protein: PNP_PELTS
Sequence: MADRSILTREIIVGGRPMILETGRLANQASGAVFVRYGDTAVLVTATVAPTVRAGIDFFPLTVDYEERFYAVGKIPGGFIKRESRPSEKAILSGRLIDRPIRPLFPKEMRNEVQVIATILSVDQDNAPEIAAMVGASAALHISEIPLKFPIGGVIVGRVDGRFVINPVLAQAEKSDMHLVVAGTKDAVMMVEAGAKEVPEEVILEAISFGHETVKEIVAFIERYREEALEMGLAKEKMVIEVAEPDPVLVEAVTGPATEKLDGVLRRCVNERLSKQERDSLLNNIKDELMQKFLADYPEQESLIKDLLDSIEKKLVRRMITEEGLRIDGRALNEVRPISVEVGVLPRPHGSGLFTRGQTQILSVVTLGTVSEEQILDGLGVEESKRFMHHYNFPPYSTGETRPLRSPGRREIGHGALAERALAAVIPGEEEFPYTIRIVSEALESNGSTSMGSVCGSTLALMDAGVPISAPVAGVAMGLIKEGDNFTVLTDIQGFEDHLGDMDFKVAGTAKGITALQMDIKIPGITREVFEKALAQAYEGRMHILNKMLEVLPAPRPELSPHAPRIIHITIDPDKIRDVIGPGGKVIKKIVEETGAEIDIEDDGRVFIAAVDQEKGRKAQEIIETLTKEVQTGEIYTGRVTRITDFGCFVEIIPGVLGMQGKEGLVHISQLAHHRVNRVEDVVKEGDVILVKVTGYDSQGRLKLSKKEATPPPESTAMKEGRAHRPSRRRESAR
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOXA_COCCA
Sequence: MDEQIVSASSNVKDGVEKQPVKDREDVDANVVPPHSTPSLPKISLISLFSIVMSLGAAAFLGALDATVVAVLTPTLAQEFHSVDAVAWYGAIYLLMSGTTQPLFGKLYNEFSPKWLFITCLIVLQLGSLVCALARNSPTFIVGRAVAGIGAGGILSGALNIVALIVPLHHRAAFTGMIGALECVALIIGPIIGGAIADNIGWRWCFWINLPIGAAVCAILLFFFHPPRSTYSASGVPRSYSEILGNLDYIGAGMIISSLVCLSLALQWGGTKYKWGDGRVVALLVVFGVLFLSASGHQYWKGEKALFPTRLLRQRGFLLSLFNGLCFGGVQYAALYYLPTWFQAIKGETRVGAGIQMLPIVGAIIGVNIVAGITISFTGRLAPFIVIATVLASVGSGLLYTFTPTKSQARIIGYQLIYGAGSGAGVQQAFIGAQAALDPADVTYASASVLLMNSMSGVITLCVCQNLFTNRINALTEVLPGVTKETLQSGFAFLRSTLTPAEFGVAIQTFNSAIQDAFLVAIVLSCASVLGWPFLSWASVKGQKKMNK
What is the function of this protein?
Putative HC-toxin efflux pump with a potential role in self-protection against and/or secretion of the toxin.
What are the official names of this protein?
Putative HC-toxin efflux carrier TOXA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACNA_FRATH
Sequence: MSDIKNITKLQIEDKGKKYSLYSLKKLSQELGKDVTRLPYSIRVLLENQLRNIDGYKVKEDDMHKVLDWDAKASSRPEIPHMPARVVMQDFTGVPAVVDLAAMRKAIKDAGGDADKINPLVDTAMVIDHSVQVDFYGTKTALAQNVAKEFERNGERYSLLKWAQKAFDDFIVVPPGMGIIHQVNLEYLAKDALVKNINGEDVIYPDTLVGTDSHTTMINGVGAVGWGVGGIEAEAVMLGQPYYMVLPDVVGVKFTGKLKTGVTATDLVLKVTEVLRKHGVVGKFVEYYGEGLESLSLPDRATIANMTPEYGATIGFFPVDEVTLDFFNNTNRSELVDAAREMYKEQLLFRENPAEEPEYSNIVEIDLSEVESNLAGPKRPQDRVAFHDMKKAFAEALVHEQGLHGFGLTDEQLQKSAEVKGLNERITHGSVAIAAITSCTNTSNPSLLLGAGLLAKKANEKGLKVKPFVKTSLAPGSQVVTQYLEKANLLPELENLGFNLVGYGCTTCIGNSGPLDEPVVEAINEADLIVASVSSGNRNFEGRINPHIKANYLASPIHVVAYALAGTVDFDPVEDAIGKDAEGNDVYLADIWPTTEEIAAIQSHVINSDMFKKAYATVLDGTEEWQKLKAPEGKLYEFDSSSTYIQCPNFFEKFAEGNDDLDIKGARTLLMLGDSVTTDHISPAGAIPEEYPAGQYLKSHGVEKKDFNSYGSRRGNHEVMMRGTFANIRIRNLLLDNVEGGFTKYHLDGSQQYVFDAAMKYKEKGIPLVILAGKEYGTGSSRDWAAKGTFLLGVKAVIAESYERIHRSNLVGMGVLPLEYVNGQNAKTLGLDGTEMFNIKNLNNIKPRQIVIVEAVHPKTAHTTTFEALARLDADVDVDYLKNGGILQTVLKDIMGDKKESKSTQSTTSKGCGSADTSSETSCPFAKIANFFKKLFK
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnA functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: ECFA_PEDPA
Sequence: MNNIIDVKNLTYKYANSGDKKALDNVSLSIEKGSWTSIVGHNGSGKSTLARSIDGLMSYNEGVINVDGIILSDDTVWDIRKKIGMIFQNPDNQFVGATVEDDVAFGLENLGIETDKMHKIVNNVLKKVRMEDFKERQPDQLSGGQKQRVAIAGVLASKPEIIILDEATSMLDPQGRYEIINLINEIHQENDITVISITHDVSEAMLSDHVIVLNDGKIVESGAPKKVFNDDEMLKLTGLEKPFNAHLFDALVEQGIHPPVELRMDENDLEEWLCQLLLKA
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA, ECF transporter A component EcfA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL3_NANEQ
Sequence: MPQHGRHAPRRGSMGFWPRKRASRIYPRIKTWPKIEEIKPLAFAAYKVGMTHTILNINGERVFTPVTVLEAPELLVIGAKAYKKENGALKEISSLYFNDLPQYVFRKIPKLKNYNFEEKKEQFLSKADNADEVKIIVSTQPWKIKLKKTPEIFDIPIGGSDVNKKLEYALSLLGKELSINDVFKEGQYVDVIAVTKGKGFQGVIKRFHVHRRQHKSEKGVRKVGAIGSRGPGRIFPTVPMPGQMGYHRRTEYNKLIIKIGEPLNVEGGWVRYGQVIGPTILLKGSVPGPRKRLIILREAIRPPRKQEKVEGIEYISLSPKN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DRP35_STAAB
Sequence: MMSQQDLPTLFYSGKSNSAVPIISESELQTITAEPWLEISKKGLQLEGLNFDRQGQLFLLDVFEGNIFKVNPETKEIKQPFVSHKANPAAIKIHKDGRLFVCYLGDFKSTGGIFAATENGDNIQDIIEDLSTTYCIDDMVFDSKGGFYFTDFRGYSTNPLGGVYYVAPDFRTVTPIIQNISVANGIALSTDEKVLWVTETTANRLHRIALEDDGVTIQPFGATIPYYFTGHEGPDSCCIDRDDNLYVAMYGQGRVLVFNKRGYPIGQILIPGRDEGHMLRSTHPQFIPGTNQLIICANDIEMGGGSMLYTVNGFAKGHQSFQFQ
What is the function of this protein?
Exhibits lactonase activity.  Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis (By similarity).
What are the official names of this protein?
Lactonase drp35.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_BLOFL
Sequence: MKFSESWIREWVNPPIDHDQLIDQFTLAGLNVEESRKLNSNKFYGIVIAKIIECQVHPSLADTWIMTVNSGGGNIINIITNNMNYNKNTKVVVANIGAILPNGNIIKQINIQGRKSEGVLCTFSMLGLNYYTQKGIIELPIDAPIGCNFYDYLHFNDNIIDINITPNRGDCLSVIGLSREIAAINQCKLKKINIKSNVPNILDTIPIIIETPHDCPKFLGKVLKNIDITIPTPLKIQEKLIRCGIQPINIITDIANYVLLELGQPVRIFDYEKIDKNIIYVRFSKPGETLTLSENNINIKLFSKTLVISDVRKPLAIAGVITGNQSSVSCSTHNIFLKVAFFNPLTIINQYKLYNLYTSSVVRYEKGIDPDISELALNYATSLLIKYCHGKAGPTINIISHNHLPKIKIIKLHRSKLNMILGFYIPDQKIINILTNLGFQVETQGHNWIVSTPSWRFDINIEENVISEIIRIYGYNHIPKIPAKISLNQTVQCIPNQVISLSKSKTVLIARGYQEIITYSFVDPNIQKLLHPQCIPLTLMNPISTNMSVMRLSLWTGLIQTMLYNQNRQHKNIKLFESGICFIPKNSHSKQVSQQLRLSGIRSGLRHYEHWDIHTSLTDFYDIKGDVESILYLFNKKNQNNNIHFKSCTYPALHPGQSAEIYLNDIFLGYVGVIHPMIQYKLRIHSNVLVFELIWDSIVNIKSQKIIDISKFPKNYRDISLIIPTHISASSVIETCKKIGIINLTEVKLIDVYTGRNIPTNFKSLTIKLTLQSKTHTLKEQEIKEIIIICTTTLKKHFNAIFR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANA_EMENI
Sequence: MKFSQALLSLASLALAAALPHASTPVYTPSTTPSPTPTPSASGSFATTSGIQFVIDGEAGYFPGSNAYWIGFLKNNSDVDLVFDHMASSGLRILRVWGFNDVNTAPTDGSVYFQLHQDGKSTINTGKDGLQRLDYVVHSAEKHGIKLIINFVNYWDDYGGMNAYMRAYGGGDKADWFENEGIQAAYQAYVEAVVKRYINSTAVFAWELANEPRCTGCEPSVLHNWIEKTSAFIKGLDEKHLVCIGDGSDGSYPFQYTEGSDFAAALTIDTIDFGTFHLYPDSWGTNNDWGKLWITSHAAACAAAGKPCLFEEYGVTSNHCAIEKQWQNAALNATGIAADLYWQYGDTLSSGPSPDDGNTFYYGSEEFECLVTNHVETIERSAK
What is the function of this protein?
Endo-1,4-mannanase that catalyzes the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans and heteromannans.  It is a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.  Active against locust bean gum and gum guar (PubMed:16844780).  Also has transglycosylation activity (PubMed:21867780, PubMed:24950755).
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase A, Endo-beta-1,4-mannanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.