PharMolix/UniProtQA huggingface dataset:
Protein: VM3AH_NAJAT
Sequence: TNTPEDDRYLQDYVYI
What is the function of this protein?
Snake venom zinc metalloprotease that causes mast cell degranulation and histamine release.  Selectively degrades the alpha-chain of human fibrinogen (FGA).
What are the official names of this protein?
Zinc metalloproteinase atrahagin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VESP_LACMU
Sequence: MSPSAGFQFSLYFLQTKKVLWKLTGLCYILLFTLCFFADQENGGKALASPPGIWKRADVTFDSNTAFSSLVVSANKKTVKNVGVPQVVPDNPERFNSSPCVLGSPGFRSGKHYFEVKYGTQREWAVGLAGKSVKRKGNLNLVPEERIWQTGLWWLRHLETDPGRVHSTSGKITVFVDYSGGNVIFDLNRIITILKANFSGEEVVPFFYLGGTVSLTTL
What is the function of this protein?
Neurotoxin that produces dose-dependent hypolocomotion and hyperalgesia in mice.  May directly act on the central nervous system, as it is 6500-fold more potent when administered intracerebroventricularly than intraperitoneal.
What are the official names of this protein?
Ohanin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ohanin/vespryn family.
What are the subcellular locations of this protein?
Secreted.
Protein: TBC23_DANRE
Sequence: MADAVGEVLEGSWNQDLADALDSAVCDLNSDQDGVIQVRDLSPPQRAKLWMIALNVSGKGDSLSSWDGVLDLPEQTLIHSRSQQLIDELGIPVEEGRDLVSDVESVITFYCKSRNVTFTPDLSWPHILKPLLGLQLSRKDLYNCFYAIMNKYIPRDCIVKGRPFHLFRLLLQYHEPEFCSFLDTKKITPDSYAINWLGSLFSSHCLPEVTQALWDVYLQQADPFLIFFLMLIILVNAKDNILIQEGDNKEEIIKMLEQSPSLLEAEDIEDLFSLAQYYNSKTPLSLRKENHNLFGSSLVALKEEDMDLSQALCLPVSVPEILQANQLQPEGVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLHNPSELALSVKSLLEAQKQSLESGSVASGEHLCFMGSGREEEDMYMNMVLAHFLQKNKEFVSIAKGGFMALQQHLADINVEGPDNVYVHWIVSTSGSHSSLSSADGELNSTDGKGVKSLVNKMTFALKSKSVNVKEKVISFIENTSTPVERHVSSSDRVGKPYRGVKPVFSIGDEEEYDTDEIDSSSISDDDRKEIVNIQTWINKPDVKHHIPCNEVKETGHMFPSHLLITATHMYCLREIAARKGFAYIQSRQALNSVVKITSKKKHPELITFKFGNNNAAGVEIVAVERYLIPNAGDATKVIKQQIMKVLDALESS
What is the function of this protein?
Putative Rab GTPase-activating protein which plays a role in vesicular trafficking.  Involved in endosome-to-Golgi trafficking.  Acts as a bridging protein by binding simultaneously to golgins, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (By similarity).  Plays a role in brain development (PubMed:28823706).  May act as a general inhibitor of innate immunity signaling (By similarity).
What are the official names of this protein?
TBC1 domain family member 23.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle.
Protein: 5BPIA_HETMG
Sequence: GTPCKCHGYIGVYWFMLAGCGYNLSCPYFLGICCVKK
What is the function of this protein?
Forms an oxidized toxin derivative (Hmg 1b-2 MexOx) (PubMed:36287966).  Able to bind T.  californica muscle-type nAChRs (PubMed:36287966).  Weakly and reversibly inhibits rat homomeric ASIC1 (isoform ASIC1a) (IC(50)=4. 8 uM), and ASIC3 (By similarity).  In vivo, induces an antihyperalgesic effect in the acid-induced muscle pain mice model (By similarity).  Molecular modeling interaction with ASIC1a suggests that this peptide hinders the collapse of acidic pockets and stabilizes nonconducting channels state (By similarity).
What are the official names of this protein?
Pi/alpha-stichotoxin-Hmg5b, Pi/Alpha-SHTX-Hmg5b, Alpha-AnmTX Hmg 1b-2.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
Protein: AOTC_XANCP
Sequence: MSLKHFLNTQDWSRAELDALLTQAALFKRNKLGSELKGKSIALVFFNPSMRTRTSFELGAFQLGGHAVVLQPGKDAWPIEFNLGTVMDGDTEEHIAEVARVLGRYVDLIGVRAFPKFVDWSKDREDQVLKSFAKYSPVPVINMETITHPCQELAHALALQEHFGTPDLRGKKYVLTWTYHPKPLNTAVANSALTIATRMGMDVTLLCPTPDYILDERYMDWAAQNVAESGGSLQVSHDIDSAYAGADVVYAKSWGALPFFGNWEPEKPIRDQYQHFIVDERKMALTNNGVFSHCLPLRRNVKATDAVMDSPNCIAIDEAENRLHVQKAIMAALVGQSRP
What is the function of this protein?
Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-acetyl-L-ornithine to produce N(2)-acetyl-L-citrulline.  This is a step in an alternative arginine biosynthesis pathway.  The enzyme has no activity with ornithine.
What are the official names of this protein?
N-acetylornithine carbamoyltransferase, N-acetyl-L-ornithine transcarbamylase, AOTCase, Acetylornithine transcarbamylase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. AOTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NICR_PSEPK
Sequence: MSKKTTPSSAPLDNTPYDVTEQVGHLLRKAYQRHTAIFQQQACDPQLTSIQFVTLCALRDHGPSSQAELIKATAVDQATIRGIVERLKARELVQLSPDPGDRRKVIVELTESGAALLDAMIPCARQISELSMGSLNAGERVAILYLLRKMIDSDENAG
What is the function of this protein?
Transcriptional repressor for the nicCDEFTP and nicXR operons, encoding the lower aerobic nicotinate degradation pathway.  Acts under non-induced conditions: repression of the nicCDEFTP and nicXR operons becomes alleviated in presence of 6-hydroxynicotinate (6HNA).
What are the official names of this protein?
HTH-type transcriptional repressor NicR, Nicotinate degradation protein R.
Protein: SYL_SALNS
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_ECOK1
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: PNP_HAEIE
Sequence: MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKDVKEGQDFFPLTVNYQERTYAAGKIPGGFFKREGRPSEGETLIARLIDRPIRPLFPEGFFNEIQVVATVVSVNPQISPDLVAMIGASAALTLSGVPFNGPIGAARVGFIDNQFVLNPTMAEQKQSRLDLVVAGTDKAVLMVESEADVLTEEQMLASVVFGHQQQQVVIEAIKEFAKEAGKPRWDWVAPQPNTDLINKVKAIAEARLGDAYRITEKQLRYEQIDAIKADVIAQITAEDEEISEGKIVDIFTALESQIVRGRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERQDHFLFHYNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPSLAEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITPEIMQIALNQAKSARMHILGVMEQAIPAPRADISDYAPRIYTMKIDPKKIKDVIGKGGATIRSLTEETGTSIDIDDDGTVKIAAVDSNAAKNVMGRIEEIVAEVEAGAIYKGKVTRLADFGAFVAIVGNKEGLVHISQIAEERVEKVSDYLQVGQEVNVKVVEIDRQGRIRLTMKDLAPKQETEINQEDPVEEQE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRABD_BOVIN
Sequence: MEEPEEQPPHEADTEPVVTSGASEAVPRVLPGDPQNLSDVDAFNLLLEMKLKRRRERPNLPHTVTELVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDERTLLREAKEISLEKLQQAIRQNGVASGLMQMLLLKVSAHITEQLGVAPGGEFREAFKEASRVPFCKFHLGDRPIPVTFKRAIAALSLWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMVGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWTTDLNIQEIMTVPPPSASGRVSRLAVKAAALGLLGYGLYWTGRRAVSLLLALPAARHCLQRLSDAWPQK
What are the official names of this protein?
TraB domain-containing protein.
Protein: PTH_DESVV
Sequence: MNISGLIIGLGNPGREYDRTRHNFGFMFIDALLEEAQRNPFARCEQLSGGKKKYDLWRCDIVEGQAPWLLAKPQTFMNLSGEAVLAIASFYRVKPAAMVVAHDELDLPLGRMRFKMGGGNAGHNGLKSITQCLGTPDFHRLRLGIGKPPAGGETTGWVLGRFSQSDTAMVDAVLEAAIQGIRTFATEGDVAATQYINAFRP
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZIN1_RAT
Sequence: MKGFIDDANYSVGLLDEGTNLGNVIDNYVYEHTLTGKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYMVKCNSTPAVLEILAALGTGFACSTKNEMALVQELGVSPENIIYTSPCKQASQIKYAAKVGVNIMTCDNEVELKKIARNHPNAKVLLHIATEDNIGGEDGNMKFGTTLKNCRHLLECAKELDVQIIGVKFHISSACKEYQVYVHALSDARCVFDMAGEFGFTMNMLDIGGGFTGTEIQLEEVNHVISPLLDIYFPEGSGIQIISEPGSYYVSSAFTLAVNIIAKKVVENDKLSSGVEKNGSDEPAFVYYMNDGVYGSFASKLSEDLNTVPEVHKKYKEDEPLFTSSLWGPSCDELDQIVESCLLPELSVGDWLIFDNMGADSLHGPSAFSDTQRPAIYFMMSLSDWYEMQDAGITSDAMMKNFFFAPSCIQLSQEDNFSTEA
What is the function of this protein?
Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake.  AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding.  Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
What are the official names of this protein?
Antizyme inhibitor 1, AZI, Ornithine decarboxylase antizyme inhibitor.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC antizyme inhibitor subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENVZ_SALTI
Sequence: MRRMRFSPRSSFARTLLLIVTLLFVSLVTTYLVVLNFAILPSLQQFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYTNEAAEEAGLRWAQHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPLFRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTRAFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMGEEDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNSVLGEVIAAESGYEREINTALQAGSIQVKMHPLSIKRAVANMVVNAARYGNCWIKVSSGTESHRAWFQVEDDGPGIKPEQRKHLFQPFVRGDSARSTSGTGLGLAIVQRIIDNHNGMLEIGTSERGGLSIRAWLPVPVARVQGTTKEA
What is the function of this protein?
Member of the two-component regulatory system EnvZ/OmpR involved in regulating expression of the outer membrane porins OmpC and OmpF as well as other genes.  Unlike E. coli or S. typhimurium both porins are expressed constitutively.  Involved in regulation of the biosynthesis of Vi polysaccharide, a capsular antigen thought to be involved in the virulence of S. typhi.  Vi antigen is synthesized at low NaCl concentrations (under 0. 4 M) (PubMed:8063417).  EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals (By similarity).
What are the official names of this protein?
Sensor histidine kinase EnvZ, Osmolarity sensor protein EnvZ.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLGL1_HORVU
Sequence: MSSMQFSSVLPLEGKACVSPVRREGSACERLKIGDSSSIRHERASRRMCNGGARGPAATGAQCVLTSDASPADTLVLRTSFRRNYADPNEVAAVILGGGTGTQLFPLTSTRATPAVPIGGCYRLIDIPMSNCFNSGINKIFVMTQFNSASLNRHIHRTYLGGGINFTDGSVEVLAATQMPGEAAGWFRGTADAVRKFIWVLEDYYKHKSIEHILILSGDQLYRMDYMELVQKHVDDNADITLSCAPVGESRASEYGLVKFDSSGRVIQFSEKPKGDDLEAMKVDTSFLNFAIDDPAKYPYIASMGVYVFKRDVLLNLLKSRYAELHDFGSEILPRALHDHNVQAYVFTDYWEDIGTIRSFFDANMALCEQPPKFEFYDPKTPFFTSPRYLPPTKSDKCRIKEAIISHGCFLRECKIEHSIIGVRSRLNSGSELKNAMMMGADSYETEDEISRLMSEGKVPIGVGENTKISNCIIDMNARIGRDVVISNKEGVQEADRPEEGYYIRSGIVVIQKNATIKDGTVV
What is the function of this protein?
This protein plays a role in synthesis of starch.  It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic/amyloplastic, ADP-glucose pyrophosphorylase, ADP-glucose synthase, AGPase S, Alpha-D-glucose-1-phosphate adenyl transferase, BEPL.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Found in the chloroplast in leaf. Found in the plastid in the developing endosperm.
Protein: UNG_FRATF
Sequence: MTWSDILAEEKQKPYFKQILDFLACESAKGKVIFPTKENIFNAFKYTELDNLKVVILGQDPYHNYNQAHGLAFSVQKWVDIPPSLQNIYKELARSIPKFKTPNHGYLVDWAKQGVFLLNTTLTVEAHKANSHKDIGWETFTDTVINKISENKHNVVFMLWGSHARKKKVLIDSSRHLILESTHPSPLSAHRGFLGCNHFVDCNKYLIEKKDQKIDWNLLC
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCHF_PASMU
Sequence: MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNTGVVPMPDPRLDALAEIVKPERVLPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFENDDIVHVAGQINPAEDIDTINTELALADLDSCERAIQRLQKRAKGGDKDAKFELSIMEKILPVLENAGMIRSIDLDKDELQAIKGYNFLTLKPTMYIANVNEDGFENNPYLDRVREIAEKEGAVVVPVCAAIESEIAELDDDEKIEFLQDLGIEEPGLNRVIRAGYKLLNLQTYFTAGVKEVRAWTIPIGATAPKSAAVIHTDFEKGFIRAEVIAYDDFIQYKGEAGAKEAGKWRLEGKDYIVQDGDVMHFRFNV
What is the function of this protein?
ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
What are the official names of this protein?
Ribosome-binding ATPase YchF.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
Protein: PAO_ARATH
Sequence: MSVVLLSSTSATITKSQSKKIPFLSPTTKFPLKVSISPSRSKLFHNPLRVAAPPSVPTSDSTEEKRIEEEYGGDKEEEGSEFKWRDHWYPVSLVEDLDPNVPTPFQLLGRDLVLWFDRNDQKWAAFDDLCPHRLAPLSEGRLDENGHLQCSYHGWSFGGCGSCTRIPQAATSGPEARAVKSPRACAIKFPTMVSQGLLFVWPDENGWDRANSIEPPRLPDDFDKPEFSTVTIQRDLFYGYDTLMENVSDPSHIDFAHHKVTGRRDRAKPLPFKVESSGPWGFQGANDDSPRITAKFVAPCYSMNKIELDAKLPIVGNQKWVIWICSFNIPMAPGKTRSIVCSARNFFQFSVPGPAWWQVVPRWYEHWTSNLVYDGDMIVLQGQEKVFLAKSMESPDYDVNKQYTKLTFTPTQADRFVLAFRNWLRRHGKSQPEWFGSTPSNQPLPSTVLTKRQMLDRFDQHTQVCSSCKGAYNSFQILKKFLVGATVFWAATAGVPSDVQIRLVLAGLSLISAASAYALHEQEKNFVFRDYVHSEIE
What is the function of this protein?
Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC).  Works in a two-step reaction with red chlorophyll catabolite reductase (RCCR).  Creates the intermediate RCC through the opening of the porphyrin macrocycle by the introduction of one atom of molecular oxygen at the alpha-methine bridge.  Seems to be specific for pheide a.  Belongs to the chlorophyll catabolic enzymes (CCEs).
What are the official names of this protein?
Pheophorbide a oxygenase, chloroplastic, AtPaO, Pheide a oxygenase, Accelerated cell death 1, Lethal leaf-spot 1 homolog, Lls1.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane.
Protein: METAA_ROSDO
Sequence: MPIKIPADLPAYDVLTREGVMVMDPDQAARQDIRPLRIGLLNLMPKKIQTENQFARLIGATPLQIELSLIRMSEHQTKNTAAEHMESFYRPFQDIKSEKFDGLIITGAPIEHLDFQDVTYWDELREVMDWTQTNVHSTFGVCWGGMAMINHFHGVRKHMLEAKAFGCFRHRNLAPASPYLRGFSDECVIPVSRWTEMRQSEIDAAEGLKTLLGSDQVGPCLVQDKAHRALYIFNHFEYDSETLKQEYDRDVAAGNQINVPLNYYPDDDPSRAPLNRWRSHAHLLYGNWLTEIYQDTPYDIDAIGR
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1941_CLOTE
Sequence: MAMRKGKEYELNIEEIEFPSMGIAYHEGLKVYVKHGIPGQKVLARITTKKKDHAKGKIIEVLEDLPYKIEAKCPAFGQCGGCAHQDIPYEKQLEIKQHEILELFKKANLDGFDFLPIEGSPKQYEYRNKMEFTFGDLKKGGELNLGMHAKGMSFGIISADECKIVDEDYRNILNATLNYFREKQLPHYRIMAREGYLRNLVIRKAENTGEVLVNLVTTSQIDFNLDEYTEIIKSINYKGNLVGILHTINDSLSDVVQCDKLNILYGRDYIIEDLLGLKFKITPLSFFQTNSKGAEKLYSIVRDFIGESKSKTVFDLYCGTGTIGQIVAPEAKKVIGIELIEEAVESARENAKLNNLNNCEFIAGDIAQVIKEVKQKPDVIILDPPRPGVHPKALEYVIKFDSPTIVYVSCNPKTLVEDLKVLVENGYVIEKVKGMDMFPSTPHVETVVGLRRKDTL
What are the official names of this protein?
Uncharacterized RNA methyltransferase CTC_01941.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: RL6_MYCSK
Sequence: MSRIGKQPVPVPAGVDVTIEGQNVSVKGPKGTLSLAVAEPIVVARDDEGAIVVTRPNDERRNRSLHGLSRTLVANLVEGVTQGYTTKMEIYGVGYRVALKGSNLEFALGYSHPVVIEPPEGITFAVETPTKFSVSGIDKQKVGQISAIIRRLRRPDPYKGKGVRYEGEQIRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CHDC_STAHJ
Sequence: MSEAAETLDGWYSLHLFYAVDWATFRLVPEDEREAMINEFKTFINDKASAREQQAGDYALYNITGQKADILLWYLRPEMKELNEIENELNKLRIADFFIQTYSYVSVIELGNYLAGKSDEDPYQNPHVRARLYPELPRTEYICFYPMDKRRNETYNWYMLPMEERKKLMYNHGMIGRQYAGKIKQFITGSVGFDDFEWGVTLFSDDVLQFKKIVYEMRFDETTARYGEFGGFYIGHILKTDDFEHFFAI
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: CAPP_STRT1
Sequence: MAFNKLESSNNQEIISEEVGILKELLDDATRGMAGEQGLTTIQHLVELYDEGDYEALTQAISEMTNDDMVFASRYFSLLPLLINISEDVDLAYEVNRKNNIDESYLGKLSETFDVVAESDNARDILENVNVVPVLTAHPTQVQRKTMLELTNHIHELLRKHRDVKDGLINKDKWYADLRRYVEIMMKTDIIREKKLKVKNEITNVMEYYNSSLIKAITKLSHEFKRLAVEKGIELDNPTPITMGMWIGGDRDGNPFVTAETLKLSATLQSEVILNYYIEKVDNLYRSFSLSSRLTEVSETVAEMAKLSPDTSVYRENEPYRRAFSYIQSKLIQTLLFFKAGNFSNERAAKRLSENVRLGSVSTGEVVADFVHDRLSQSLQAVSQQTTEFYETAEAFHDDLLAIKNSLLENDDSVLISGDFEELLQAVEVFGFYLATIDMRQDSSVHEACVAELLKSANIVDNYSELTEVEKVAVLLKELQEDPRTLSSTNVSKSETLEKELAIFRTARLLKDYLGEEVIKQHIISHTESVSDMFELAILLKEVGLVDTERARVQIVPLFETIEDLENSNEIMKQYLGYDIVKRWIKNSNNYQEIMLGYSDSNKDGGYLSSGWTLYKAQNELTNIGEERGIKITFFHGRGGTVGRGGGPSYDAITSQPFGTIKDRIRLTEQGEVIGNKYGNKDAAYYNLEMLVSATLDRMVTRQITDPDELVDFREIMDSIVQDSNRIYRDLVFGNEHFYDYFFEASPIKEVSSLNIGSRPAARKTITDISGLRAIPWVFSWSQNRIMLPGWYGVGSAFNHYIEAEEGNLEKLQHMFETWPFFRSLLSNVDMVLSKSDMNIAFHYAQLAESEEVRSVFNIILDEWQLTKNVILAIEKHDDFLEESPSLKASLGFRLPYFNVLNYIQIELIKRLRNNNLTDDEISLIHITINGIATGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: KLH10_HUMAN
Sequence: MEMESAAASTRFHQPHMERKMSAMACEIFNELRLEGKLCDVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISILLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLGNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVEEYAARRDNFPGLALRDEVKYSASTSTLPV
What is the function of this protein?
May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis.
What are the official names of this protein?
Kelch-like protein 10.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_HALH5
Sequence: MKGISVLGATGSIGTQTLDVLANHRDKFRLVAMSVGKNLTLAEEQIHQFKPPLVSVMTDEDRKTLASKVPEGTRVVCGEEGLIEVATAEKAEILVNAVIGSVGLAPTLAAIEAKKTIALANKETLVTAGHLVTEKAREHGVKLLPVDSEHSAIFQALQGERMDRLHRIIITASGGSFRDKSRDELNGVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIEAHWLFNLPYEKIDVLLHKESIIHSMVEFVDRSVIAQLGTPDMRVPIQYALSYPDRLEFHEGQQLNLWEVGKLHFAPLDMERFRCMAFAYESGKQGGTMPTVLNAANEEAVELFLNNQLSFLGIEDVIEKALERHERIDSPSLADILHVDQETRAFVHSLIK
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: PROA_HELMI
Sequence: MIVYSELSLKGKKAKDAAYKLGSLSSQVKNKALEAMAYALVAQEEEILAANALDMEAGRQKGMSKALLDRLMLNKKRIEEMAEGLYALVSLPDPIGEVKRQWRRPNGLEIGQVRVPLGVVGIIYEARPNVTVDAAGLCLKTGNAVILRGGSEAIRSNMAIVKAISKASEEAGIPEGAIQLVEDSSREVAQQMMTMNEYLDVLIPRGGAGLIQAVVKNATVPVIETGVGNCHIYVDADADLEMAEKIIINAKCQRPGVCNAAESLLVHQDVARKFIPHIGKVLTEMNVELRGCPRTLSLFSGIKEATDEDYATEFLDLILAVKIVDSFDEALEHIRKYSTGHSEAIVTRDYSRAREFTRRVDAAAVYVNASTRFTDGFQFGMGAEIGISTQKLHARGPMGLNELTTIKYVCYGDGQIR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.