PharMolix/UniProtQA huggingface dataset:
Protein: SSBP_RAT
Sequence: MFRRPVLQVFRQFVRQESEVASSLVLERSLNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGDNEAYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGARIFVEGKVDYGEYMDKNNVRRQATTIIADNIIFLSDQAREKPLNG
What is the function of this protein?
Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA).  In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays a crucial role during mtDNA replication by stimulating the activity of the replisome components POLG and TWNK at the replication fork.  Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity.  In addition it is able to promote the 5'-3' unwinding activity of the mtDNA helicase TWNK.  May also function in mtDNA repair.
What are the official names of this protein?
Single-stranded DNA-binding protein, mitochondrial, Mt-SSB, MtSSB, Single strand DNA-binding protein P16.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein: RS2_BACFN
Sequence: MSRTNFDTLLEAGCHFGHLKRKWNPAMAPYIFMERNGIHIIDLHKTVAKVDEAAEALKQIAKSGKKVLFVATKKQAKQVVAEKAASVNMPYVIERWPGGMLTNFPTIRKAVKKMTTIDKLTADGTYSNLSKREILQISRQRAKLDKTLGSIADLTRLPSALFVIDVMKENIAVREANRLGIPVFGIVDTNSDPTNIDFVIPANDDATKSVEVILDACCAAMIEGLEERKAEKIDMEAAGEAPANKGKKKSAKARLDKSDEEAINAAKAAAFLKEDEEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL5_PYRFU
Sequence: MAVEIPNKEQILADWEAHPMRRPRIEKVTINIGVGESGERLTKAEIMLQQLTGQKPIRRKAKKTNRDFGIRRGEPIAVKVTLRGPKAYELLKRLLAAVDNRLKASSFDEHGNVCFGIEEHINIPGVEYDPEIGIFGMDVCVTLERPGFRVARRKRKRAKIPTRHKLTKEEGMVYMMEEFGVEIVEG
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5, Large ribosomal subunit protein uL5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NSE1_BOVIN
Sequence: MQGNTRRTGVMTDVHRRFLQLLMTHGVLEECDVKRLQKHCYKVHDCNATVEKLEDFINTINSVLESLYIEIKKGVTEDDGRPIYALVNLATTSVSKMASDFAENELDLFRKALELIIDSDTGFASSTNILNLVDQLKGKKMRKKEAEHVLQKFVQNKWLIEKEGEFTLHGRAILEMDQYIRETYPDAVKVCNICRSLLIQGQSCETCGIRMHLPCVAKYFQSSSEPHCPHCNDYWPHEVPEVFDPEKERETGMSRSNKRPSRSRQH
What is the function of this protein?
RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate.  Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex.  Involved in maintenance of genome integrity, DNA damage response and DNA repair.  NSMCE3/MAGEG1 and NSMCE1 ubiquitin ligase are components of SMC5-SMC6 complex and may positively regulate homologous recombination-mediated DNA repair.
What are the official names of this protein?
Non-structural maintenance of chromosomes element 1 homolog, Non-SMC element 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NSE1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: DADA2_RALSO
Sequence: MQITVVGAGIVGISTAYALAQEGHQVTLVERNPGPGEGTSYANGGQLSYSYVAPLAGPGVLSHVPGWLLRRDSPLRLKPSLDPVLLRWGLRFIAACNRERADRTTRELLALSFYSRARMEALRAASPDLSFSFARRGKLVVYRDAAAFASARAQVGYQATLGCEQHALSADETIAREPALAGARGAIVGAIYTPDEDVADCHQLCVGLFNRLCALPNVALRFNAGAESLWVEGRRVRGVRTAHEPITADAVVVAAGVASAGLLGPLRIDPGLYPLKGYSISLPLGEGGAGSDGAPVVSVTDAARKIVYARIGRTLRVAGMADLVGWSDRLDPRRVQTLYDETRALFPAALRASDAGADAAPWAGMRPATPTGVPVVGPSPVDGLWLNVGHGALGFTLAMGSAGLLADLIARRAPAIAAAPYALAR
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: Y093_HAEIN
Sequence: MQLDKYTAKKIVKRAMKIIHHSVNVMDHDGVIIASGNSTRLNQRHTGAVLALRENRVVEIDQALAQKWNFEAQPGINLPIHYLGKNIGVVGISGEPTQVKQYAELVKMTAELIVEQQALLEQESWHRRYKEEFILQLLHCNLNWKEMEQQAKFFSFDLNKSRVVVLIKLLNPALDNLQNLINYLEQSEFAQDVAILSLDQVVVLKTWQNSTVLSAQMKTLLPADYSKQDYKIAVGACLNLPLFEQLPLSFQSAQSTLSYGLKHHPRKGIYVFDEHRLPVLLAGLSHSWQGNELIKPLSPLFSEENAILYKTLQQYFLSNCDLYLTAEKLFVHPNTLRYRLNKIEQITGLFFNKIDDKLTLYLGTLLEH
What are the official names of this protein?
Uncharacterized protein HI_0093.
What is the protein family that this protein belongs to?
Belongs to the CdaR family.
Protein: C9B16_SOYBN
Sequence: MISESLLLVFLIVFISASLLKLLFVRENKPKAHLKNPPSPPAIPIIGHLHLLKPLIHHSFRDLSLRYGPLLSLRIGSVKFIVASTPSLAQEFLKTNELTYSSRKMNMAINMVTYHNATFAFAPYDTYWKFMKKLSTTELLGNKTLGHFLPIRTREVHDIIQFLFHKSKAQESVNLTEALLSLSNNVISQMMLSIKSSGTDSQAEQARTLVREVTQIFGEFNVSDFLGFCKNLDLQGFRKRALDIHKRYDALLEKIISDREELRRKSKVDGCEDGDDEKVKDFLDILLDVAEQKECEVQLTRNHVKSLILDYFTAATDTTAISVEWTIAELFNNPKVLKKAQEEVDRVTGNTQLVCEADIPNLPYIHAIIKETMRLHPPIPMIMRKGIEDCVVNGNMIPKGSIVCVNIWAMGRDPNIWKNPLEFKPERFLEGEGSAIDTKGHHFELLPFGSGRRGCPGMPLAMRELPTIIGALIQCFEWKMLGSQGEILDHGRSLISMDERPGLTAPRANDLIGIPVARLNPTPFRQM
What is the function of this protein?
Functions as flavone synthase II (FNSII) that catalyzes the direct conversion of flavanones to flavones (PubMed:20132953).  In vitro, can convert liquiritigenin, naringenin and eriodictyol to 7,4'-dihydroxyflavone, apigenin and luteolin, respectively (PubMed:20132953).
What are the official names of this protein?
Cytochrome P450 93B16, Flavone synthase II, GmFNSII.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NACH_DROVI
Sequence: AAFAYFSGFMLDDARFSPAEIELMESVLLDNNLTMVQFVDRLRWDCHELLHRCRYHGDIMDCTQLFQLSKTFFGHCCSFNLRQHGLDFTAQAAAGGLDNGLSLILRYKDENYDALQSYSHGFKLLIQETDAFPSAHADCKFLGLNTESFATLRVVETFCSEAVKSLPISQRNCVFRHEFRLRYFSDYVYPNCELNCRAKNMVKLCGCHTYFFEFNRTKDRVCTFRDIPCLVDNFPDIITRRKKTQCNCPLTCEHFDYDVQMSNFALMLNMPVVDPFYTGIERNDAIVHIFLNSQVYRRVRVDLLSNMVTLVSHLGSAFSLFVGMSMLSLVEIIYYFTVILRRNYVQECRARQKLQTLHRRPNFGWPGDKNSNQQKSVFYIRGRN
What is the function of this protein?
Part of a complex that plays a role in tracheal liquid clearance.  Probable role in sodium transport (By similarity).
What are the official names of this protein?
Sodium channel protein Nach.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1244_HAEIN
Sequence: MNPFQKIKSAVNKRQRFFINRTLQRKLTNQGMTVISANCVGAFILHDLHQPFNSPFVNLYLSPQDFLRYLQNIDFYLTQPLTFVQTEKSYPVGKLADLEIHFMHYHSEQEANEKWQLRTSRMKLDNLFIMMTDRDGVTEKDIQLFDQLPFKNKVIFTHKPYPAFKSAYYIKGFEKQNQVGDIFEFSGWNGKKYYDQFDYVKWFNHA
What are the official names of this protein?
Uncharacterized protein HI_1244.
Protein: KR510_HUMAN
Sequence: MGCCGCSGGCGSGCGGCGSGCGGCGSGCGGYGSGCGGCGSSCCVPVCCCKPVCCCVPACSCSSCGSCGGSKGDCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGCSQCNCCKPCCCSSGCGSCCQSSCCNPCCCQSSCCVPVCCQSSCCKPCCCQSSCCVPVCCQCKI
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 5-10, Keratin-associated protein 5.10, Ultrahigh sulfur keratin-associated protein 5.10.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 5 family.
Protein: PUM24_ARATH
Sequence: MSSKGLKPQKSTKRKDTDSSAKFDSLKSKKPKLVSGEQQQHVKPKFGKPKSAGDKEQSTNLSKKERRVQAKELTEARKKKRKPHYNLEQELVSLWEKMRRRNIGKEDRSKLISEAIRKMKGKVPEIAVSHVSSRVLQTCVKFCSQAEKDVLFTELQPQFLNLASNKYAVHFIQKMLDGASKQQLAACISSLRGHVAPLLRHVFGSLVVEHAYHLGSAAQKQELLAELYSTELQLFKGLTTSNEKTVVDIIAKLGLQKGAVNRHMTAIIQPILEKGIVDHTITHKLLIEYLTIADKTSAADVLQLLTGSLLLRMVHTRDGSRLAMLSIKHGSAKERKKIIKAMKEHVKKMAFDQFGSMVLACIFSIVDDTKLVTKIIVRELEATLKDLVMDKNGRRPLLQLLHPNSSRYLSHDDLAALDLSVPSLCSMDKSETSSKTKDTDGNEIGEETKDEQEDTVAEHSDHEENVTAMGGKKDPLVRRQELLVNSGLAERLIDVCVENAEEFLQSKFGNEVMYEVAIGGSDGILCPSLSEKLCELYEAISSVAAEPKPQESEKDSEHILENFHSSRTIRRLVLNRPGFASILFKKALSGKCRSWAQGHCSKILSAFVETEDVQVREMAKTELQVLVNEGTLKISATKKPE
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
What are the official names of this protein?
Pumilio homolog 24, APUM-24, AtPUM24.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PCNA_METPE
Sequence: MLDATIDADVFRESVDAIAALVTECRLHATEQGLRTRTVDTANVAMISLELDKDVFESYQATSSEMGIDIVKIKNVLSMMGKGDPVHLALAEESRKLEVSFQSYQYSITLLDTNTIRKDPNAPTIELPGKVVISGAALSAAIKAASVVSDKIALGIDPEKGIFYMEAEGDTDHIRLELGDDKLISLVPVQARSLFSLDYLKDMGKTMSKAEKVEISLGIDHPVEFTFDIADGKGHVMYLLAPRIEAD
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: TRUA_FINM2
Sequence: MKNIKLTVQYDGSKFYGWQKLNDLPSVQLEIEKAVTKMVHQPVKINGAGRTDKGVHAKGQVCNFIVDTDISANQFLMGVNHFTSDSIVIVKSEEMDLDFHARFSAKSKTYKYILCNKYYMEPWFNDYKGHRKYYLDFDLLLKCRDMLIGKHDFTSFVNDLEEDINPVRTIDEITIEKIDDDIVFTFKAESFLRNMVRILVGSMVDVARGRKSIDWLKNALENKDRQSAGITIEPSGLYLMDIEY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PSAE_SYNP6
Sequence: MAIARGDKVRILRPESYWFNEVGTVASVDQSGIKYPVVVRFEKVNYNGFSGSDGGVNTNNFAEAELQVVAAAAKK
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV, Photosystem I 8.1 kDa protein, p30 protein.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ACP_PHYAS
Sequence: MVLEKIKTLMVNQLSLDSQSITLKTRFREDLGLDSLDALELMMELEKIFNVSISDTTLQNFKTVEDVVLYIEKNLA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAER_STAAB
Sequence: MTHLLIVDDEQDIVDICQTYFEYEGYKVTTTTSGKEAISLLSNDIDIMVLDIMMPEVNGYDIVKEMKRQKLDIPFIYLTAKTQEHDTIYALTLGADDYVKKPFSPRELVLRINNLLTRMKKYHHQPVEQLSFDELTLINLSKVVTVNGHEVPMRIKEFELLWYLASRENEVISKSELLEKVWGYDYYEDANTVNVHIHRIREKLEKESFTTYTITTVWGLGYKFERSR
What is the function of this protein?
Member of the two-component regulatory system SaeR/SaeS involved in the regulation of staphylococcal virulence factors in a strain-dependent fashion.  Probably functions as a transcriptional regulator via a specific DNA-binding domain, recognizing motifs near the promoter sequences of target genes (By similarity).
What are the official names of this protein?
Response regulator SaeR, Staphylococcus exoprotein expression protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_DESPS
Sequence: MFSGVVMAWQKAQGCLKESLSKDVYSLWIAPLESVRQENGVVSLAGPDRYFIAFVKQNYLKEIERSLTGVDSSITDVRFLEKKAVPQLRSMMHRTSTSAPTFPVPSVSSASTASTASTASSASSVPRQLRLPSVPKNNASIRALHPRYTFDEFMVGQSNILAESACRAISADADTVGPCLYINSGTGLGKSHLTHAVAHHLLSNSPMTRMHYVTAQQFSAEMVHGIKNNSMDMFKKKYQEDCDILLVEDIHTLKGKKKTQEELNEVLDTLVKSGKRVLLTANAAPRELAGIDGEFRSRMSAGLITSIQAPDIKTRSRIVERKAAGQRLSFDEDMTSYLAQNVRGDVRQIESAITAIGARARLMGGYIDMNLIREVVGSVVGCNQSLSSSLIRDLISAQFQVSVEDLQSRSRKKSISLPRQIAMYLSRKFTEESLAEIGRTYKRDHSTVIHSVKVITDKARRDMSLGAQVNLLSDKVKQI
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_PHOLL
Sequence: MEKTPATQTQAEPSLDKTYNPKEIEQPLYNHWEKSGYFKPNGDTSRESFCIVIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQSGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWQWKAESGGTITNQMRRLGNSVDWERERFTMDEGLSNAVKEAFVRLYQENLIYRGKRLVNWDPKLHTAISDLEVENREVKGSMWHLRYPLADGVTTAEGKDYLIVATTRPETMLGDTGVAVNPEDPRYKDLIGKEIILPLINRRIPIIGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINIMTFDGNIRHKAEVFDTHGEISDSYSSDIPAEYQGIERFAARKTIVAEFERLGLLVEIKAHDLTVPYGDRGGVVIEPMLTDQWYVRTAPLAKVAIEAVENGDIQFVPKQYENMYYSWMRDIQDWCISRQLWWGHRIPAWYDTNGNVYVGRSEEEVRRENNLGTDISLNQDEDVLDTWFSSGLWTFSTLGWPEQTDALKTFHPTDVLVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFKTVYMTGLIRDEEGQKMSKSKGNVIDPLDMVDGISLEELLEKRTGNMMQPQLAEKIRKRTEKQFPAGIETHGTDALRFTLAALASTGRDINWDMKRLQGYRNFCNKLWNASRFVLMNTEGQDCGQHGGEMALSLADRWILAEFNQTVKAYREALDTYRFDMAANILYEFTWNQFCDWYLELSKPAINKGSEAEVRGARHTLIEVLEGLLRLAHPIIPFITETIWQRVKIVKGIEADTIMLQPFPEFAQEKTDELALTDLEWIKEAIIAVRNIRAEMNIAPGKPLEVLLRNADAGAQRRVAENLNFIQAMGRLSSVTLLSTDEEAPISVTKLINGAEVLIPMAGLVDKEAELSRLNKEIEKLDKEIGAIEGKLSNEGFVSRAPEAVVTKERERLANCNTSKEKLLAQKETIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_BURP0
Sequence: MSGLPIATNLYFDAHFHRHGVKLLPNEFYTTREDMVLVTVLGSCVAACLHDPIGRIGGMNHFMLPDDGADPSAAASESMRYGAYAMEVLINELIKAGGRRERFEAKVFGGAAVLAGMTTINIGDRNADFVRRYLALERIRITAEDLQGVHPRKVAFMPHTGQAMVKKLRVQAPDVAAREAALAREAVDPHGERAPRVRPRVELFGTPAPKAQAKPRIELFGMRATQPATRKQEA
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: LGT_BURPS
Sequence: MIIHPNFDPVAIHLGPLAVRWYGLMYLVGFILAIVVGRLRLKLPHVAAQGWSAKDIDDMMFYGVLGVVLGGRLGYVLFYKAGYYFSHPLDIFRVWEGGMSFHGGFLGVTLAMALFAWQRKRHWLEVTDFVAPMVPTGLAAGRLGNFINGELWGRVTSPDAPWAMLFPGASRDDAAWLAAHQDIAAKWNLNEVFLSHQMLPRHPSQLYEIALEGIALFFVLWFFSRKPRPMGAISALFLIGYGAARFTVEFAREPDDFLGLLTFGLSMGQWLSLPMIVAGVLMMIWAYRRGGVAKQA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCDGB_PANTR
Sequence: MANRLQRGDRSRLLLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHIWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLQLRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSEASDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSRLLQASEGGLAGMPTSHFVGVDGVQAFLQTYSHEVSLIADSQKSHLIFPQPNYGDTLISQESCEKSEPLLIAEDSAIILGKCDPTSNQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-A11, PCDH-gamma-A11.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: B3GLT_HUMAN
Sequence: MRPPACWWLLAPPALLALLTCSLAFGLASEDTKKEVKQSQDLEKSGISRKNDIDLKGIVFVIQSQSNSFHAKRAEQLKKSILKQAADLTQELPSVLLLHQLAKQEGAWTILPLLPHFSVTYSRNSSWIFFCEEETRIQIPKLLETLRRYDPSKEWFLGKALHDEEATIIHHYAFSENPTVFKYPDFAAGWALSIPLVNKLTKRLKSESLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTNDVDFYCATTFHSFLPLCRKPVKKKDIFVAVKTCKKFHGDRIPIVKQTWESQASLIEYYSDYTENSIPTVDLGIPNTDRGHCGKTFAILERFLNRSQDKTAWLVIVDDDTLISISRLQHLLSCYDSGEPVFLGERYGYGLGTGGYSYITGGGGMVFSREAVRRLLASKCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQARPVDYPKDYLSHQVPISFHKHWNIDPVKVYFTWLAPSDEDKARQETQKGFREEL
What is the function of this protein?
O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage.  Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
What are the official names of this protein?
Beta-1,3-glucosyltransferase, Beta3Glc-T, Beta 3-glucosyltransferase, Beta-3-glycosyltransferase-like.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: MSHR_LORTA
Sequence: MPAQGSQRSLLGSLNSTLMATSSLGLSANQSGPQCLEVSVPDGLFLCLGLVSLVENMLVVAAIAKNRNLHSPMYCFICCLALSDLLVSVSNVLETAVMLLLEAGALAAQATVVQQLDNIIDVLVCSSMVSSLCFLGAIAMDRYISIFYALRYHSIVTLSRAQWATAAVWAAGILSSTLFIAYYDHTAVLLCLVVFFLAMLVLMAVLYAHMLTQACQHVQGITRLHKRQHLVQQGFGLKGAATLTILLGVFLLCWGPFFLHLTLIAVCPQHPTCSCVFKNFKLFLALIICNAIVDPLIYAFRXQELRKTLKEVLLFSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S13A1_MOUSE
Sequence: MKLLNYALVYRRFLLVVFTILVFLPLPLIIRTKEAQCAYILFVIAIFWITEALPLSITALLPGLMFPMFGIMRSSQVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQIISAEAEAEATQMTYFNESAAHGLDIDETVIGQETNEKKEKTKPAPGSSHDKGKVSRKMETEKNAVTGAKYRSRKDHMMCKLMCLSVAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDCRCLNFGSWFLFSFPVALILLLLSWIWLQWLYLGFDFKMFKCGKTKTLKEKACAKVIKQEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVAGILFFLIPAKKVTKMTSAGEIIAFDYTPLITWKEFQSFMPWDIAILVGGGFALADGCQVSGLSNWIGSKLSPLGSLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAIQVNPLQILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGMFTWIEPMFNLHEYPSWASNFVNQTMP
What is the function of this protein?
Sodium:sulfate symporter that mediates sulfate reabsorption in the kidney and small intestine (PubMed:10766815).  Can also mediate the transport of selenate and thiosulfate (By similarity).
What are the official names of this protein?
Solute carrier family 13 member 1, NaSi-1, Renal sodium/sulfate cotransporter, Na(+)/sulfate cotransporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HEMA_I54A2
Sequence: MKARLLILLCALSATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGKCNIAGWILGNPECESLLSNRSWSYIAETPNSENGICYPGDFADYEELREQLSSVSSFERFEIFPKESSWPKHNITRGVTVACSHAKKSSFYKNLLWLTEANGLYPSLSKSYVNDREKEVLVLWGVHHPSNIEDQRTLYRKENAYVSVVSSNYNRRFTPEIAERPKVRGQPGRMNYYWTLLEPGDKIIFEANGNLIAPWYAFALSRGPGSGIITSNASMDECDTKCQTPQGAINSSLPFQNIHPVTIGECPKYVRSTKLRMVTGLRNIPSIQSRGLFGAIAGFIEGGWTGMVDGWYGYHHQNEQGSGYAADQKSTQNAINGITNKVNSVIEKMNTQFTAVGKEFNKLEKRMENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVKNLYEKVKNQLRNNAKEIGNGCFEFYHKCDNECMESVKNGTYDYPKYSEESKLNRAKIDGVKLESMGVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.