PharMolix/UniProtQA huggingface dataset:
Protein: PMIP_PLEDJ
Sequence: MLTRPAQNALLKSMQPLFRFRGCLLAKSTSTPRRDISTSSRKLAHPTTVPIPPSVDDHALVALLDQPSSFGIVSRLFQTQGGLFGHKELQQPSGFITLAEATLVRAQILTNRILRARESQDELRKVVKNLDRLSDMLCGVIDLAELVRNAHPDRAWVEAANQAYETLCEFMNVLNTDVGLYDVLKAVLSDPTIVQGMGPEEYSTAQIFWHDFEKSAINLPPEQRQRFVSLSSEILVLGREFLQEANTARPPASIHASELAGLKDKGMGARLQLQAQFTQKDLLVYPGSLQAQMIMRCAPAEEPRRKLYIAANSSTPSQIELLERLLRTRAELARLVGKESFAHMTLSDKMAKSPENVQYFLDALMDYTRPYARKALRTLSMRKQAHLQTPPFPTIQPWDRDFYCPPEPPAPPIPLPPLTLGTVFAGLSRLFYHLYGISLRPAECAPGEVWHPHVHKLEVVDEDAGVIGWIYADLFARRGKPSGAAHYTVRCSRRTDDDDEAEDGSIPAAEPYVRVSQSFESSKRHRVRGQDGEFQLPLVVLVCEFARPSVSSGPTVLDWHEVMTLFHEMGHAMHSMIGRTEYQNVSGTRCATDFVELPSILMEHFLSSPTVLSLFDVSSSTPSSAWQVGNHHQDPCHSIDTHSQILLAAMDQIYHSPSVVDPSFSSTSALEALHKSRGLIPYVPGTSFQTQFGHLFGYGATYYSYLFDRAIASRVWSQVFHANPLNRELGDKYKREVLKFGGGRDPWKMISHLLDSPWLENGNADAMKEVGQWRIEDEVGQPGRH
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase, MIP, Octapeptidyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MAP2_CANAW
Sequence: MAGATEGEDTKVIESKINELNIDKPKLEDNNEAKGNGNGNESGGDDDDDKEDDDDNDEITEPSTSTSSGDKKKKKNKNKKKKKKKIVSIDSSYPEGIFPEGQWMEYPLEDINSYRTTSEEKRYLDRQQNNKWQDFRKGAEIHRRVRHKAQSSIRPGMTMIEIANLIEDSVRNYSGNDHTLKAGIGFPTGLSLNHVAAHYTPNTGDKLILKKDDIMKVDIGVHVNGRICDSAFTMTFNEDGKYDTIMQAVKEATYTGIKESGIDVRLNDIGAAIQEVMESYEMEENGKTYPIKCIKNLNGHNIDDFVIHSGKSVPIIANGDMTKMEEGETFAIETFGSTGNGYVLPEGECSHYAMNKGVEHLKPPSERSKQLLETIKQNFGTLPWCRRYLERTGEEKYLFALNQLVRHGIVEEYPPIVDKRGSYTAQFEHTILLHPHKKEVVTKGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIRC8_GORGO
Sequence: MTGYEAWLITFGTWMYSVNKEQLARAGFYAIGQEDKIQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDIKKIMEEKIQTSGSNYKTLEVLVADLVSAQKDTTENESNQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCNAVIDFKQRVFMS
What is the function of this protein?
Protects against apoptosis mediated by BAX.
What are the official names of this protein?
Baculoviral IAP repeat-containing protein 8, Inhibitor of apoptosis-like protein 2, IAP-like protein 2, ILP-2.
What is the protein family that this protein belongs to?
Belongs to the IAP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RABT1_DICDI
Sequence: MKEETTTTTTTTTTKNTTKIIRNEDDDYELVKVIILGDNKTGKSSILRRYHYNEFELGVSSIGVDFIKKDYGMVNGKYYKIQIWDVNSCDRFRLLTHSYYKGAHGFMLLYDCTNQESFNNLQFWINEIINKSPNSNNSTIVIIGNKCDLVNGIKIDPIKSKQFCDSKSITSFQNVSAKDSININEPFEILFRQIIKKGHSQTVSPKHDTYENNNINKSCNIL
What are the official names of this protein?
Ras-related protein RabT1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RSMB_HAEIN
Sequence: MKKFSSKTIKAKNSVKMTALSTRAIAANLILQVLDEGKSLSALIPEVQLSVKAQDLPLLQEICFGVCRVLPRLEQIIKRLVDKPLKGKTRIVHCLLLVGLYQLLYMRVPAHAAVDEVVNATKSLKSDSFRGLVNAVLRRFLREQDEILAIIDKNWQTLHPEWFVNKLKKAYPNWREIIEANNQKPPMWLRVNSQKNALETYRTLLEEQGVSSKTSHHPNALCLDIPIAVQKLPHFEEGAVTVQDLSAQWAATLLEPKNEEWILDACAAPGGKTTHILELAPQANVIALDVESHRLKRVEENLERLNQQAIVVCGDASKPDEWLAEIGKSAAKFDRILLDAPCSATGVIRRHPDIKWLRKETDIAQLVELQKKILSALWEKLKPNGVLLYATCSVLPEENCEQIQAFLNAHADAELLSLPFSDDKSAVGFQFIPQPNSGDGFYYAKLLKRAS
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSN2_DEBHA
Sequence: MPEAIDASSIATNYYKLAHLCSVTYLIYTTNGATNDSTLLELELLIRHSHPKCLVTYYNKYLYYFQFNHVDEHVDLTKEYPQLQLKYSNQVSADLLANPPKVASDKDNHSTGNEYLAYACLSFLKAVKKLVLFNLSRNEAVQLFGNYAVVKEQGLSNFILHIDPILLPNGDLLISISEKCHLQLFDSSIVDISEIEAVDLNFVLYIIPSGIRCHLYDNVNVASNFTTDPPKNSEVLMQLIKYSTGFDLNQLNSLVWVKLVPNLQHLNNQTSKISKFIHPVDNKKFILWPWRLCLLQFGLSEKDTATSPHVLTCDPISLISDFIDFNISHHQQANITGQLNPNHQHNQSFNYSIPSALSTGMSSTGANENKGDLNMVGDIPGSVSDIFGIQSSDTNDFFNGPNFQPAQNPSDVKLDSQEPVKKNSDDEDVEMDDLFGDASEDEKAKTEVSTNELNEEKNFEDLFNDGLNQENQVDESDKVAKSIDEEVLKEESVKSEDLKEDKDLKMQPSSGTIPNTFIDIPKDQMTIPSLKNLKQTPQIYNDPGAPMPVIPTPIFPQFGINSTLPGSAQSVNPPTSAAATDNEANEGARSIFSPILFNPIIKSNIDTKYGKGGKFYVDKEVSAGPDIDSKRKTLRATSVSGFELPSRREDSIGIESITDDNDRRQVFEFPEEQGNERMKDEGHENHAAENDNIIKKMEELEEEDDNDDDDDDDDDDDENEDEDEESDEDDDLNLENNDMNMKRSPPLKLNTLNDPYVAQSNQAVVNFNDSNYNAKQILPNSYNASSMNTGGFSSPASLGFSSSRTNVPPKNDSPFGLNNLAREDRNGTTSPTGDNSDQPTKRQEQSDSPMVVDMEVEKKSTSKEAENTPSGMTTPNSRGSISESSNCLPLILRGVNVASIPTSFILNNVIVSNKISTISTNFDMDVDDETEWSDYELCKNNEMTVKLNNLDEFLKCLGPNLIFDMGLNKLQNSLEMKLSNNERDDEEYDNIEGKAPSRQFENKLCDIFPFCYKVNLNEFTTEAYVNELKGETTTIQDELDNQLSFLDDITNEDILNPKTQLKKLNSIEWDAIYSDSSSNEDNSKKYQGMVHNVGQSSLVNTLEDGTIFPLANDKARVLKHNDTIINLNSIGIKFWKYLNFSPLNGPKNFQLLLISEHDHNMLHHNYNIEFLNSLVYNYKECCFGNISKINLQSSDSRPDMEGIDNGLLMVHKKDEDQVYGNMYKQVNRKLNALVEMIKSDLINKTNKFEFDRPLLLLFINFDKSVNSLLQISKLIRNFKLFLSHHQLPLVEVFAHIIPWSLIIKQSGSQRRLKYLSNFRLSKLSMNLYNQCPNERTIGKPVKDPTKHLFTQLVKEPPSNLNFKFMNNGSNGNGKTTFNDDIFLHLAYERSIDKNWFSAAWSDPLGVVVSTKSWNCSPNLQKTNNKNVHSLESISDEIWTISTALFKKLNDEIIKRTSGLGGKKFLVLTRINSIIPDDELIHWKRLSMKHKDVSLIVLSVNKSPKLLFSGPIGPSQQEDKSNYDPNTNRTSTNMDNSSSTNAANPTCGVGATSNAPDFFKTFGSNNPSPNNNAGSMSISPSNNVGINFHSPQQFLNAPGNFLLPQDFVSSTGGSTNINANPHSNASQYNPDEIIHDPTEELTAVIPKAPLPSFNSPTRLGMKIGYLIKETGVSTHEDTKQYLVYEINLLSCSNYWNLNAIMKILLNQYKKLITLNDILCVGEIDGSITDDRAEKDSNIIPEMTPPLNYTASGLIPWHIAAVTKSLDYLIHIDVEE
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 13, Mediator complex subunit 13.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_BORGP
Sequence: MDLIRKIEAQNKKSEAFVFNVGDTVRVIYKIIEGSNERLQSFEGIIISFQNKGIGKTFLVRKISSGIGVEKIFPVYSPIIEKVEVLRRGKVRRAKLYYMRNRIGKAAMKIKERLNIKKVKH
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: TMED8_PONAB
Sequence: MSDLQAAEGPGSWSPTARPGSAGGVGDCQGVEGSQAAASENEDLENNKDTSLLASATDPEPCSPPHRPQMVSPGSKDATEDLRKATGALEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSCDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHIYYTS
What are the official names of this protein?
Protein TMED8.
Protein: GATC_DROAN
Sequence: MLRLLNKRFYCKFATKTKVRPEKLNFKQLTHPTKVPQTPVKAAFPNTSANEIELDPKSIQLLERLALVDLDSERALETLKSSIQFADKITHIQTDNVRPLYTVLEQQQLQLRNDLVTEGDCRGKVLSNAKVTDEDYFVSPPGNIPLEQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial, Glu-AdT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NOP10_DICDI
Sequence: MHLMYYNDKDGQRVYTLKKESPNHEATYSAHPARFSVDDKYSRERIALKKRFGLLLTQQPPLEF
What is the function of this protein?
Required for ribosome biogenesis.  Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (By similarity).
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit 3, Nucleolar protein 10, Nucleolar protein family A member 3, snoRNP protein NOP10 homolog.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: OSTCN_CAPHI
Sequence: YLDPGLGAPAPYPDPLEPKREVCELNPDCDELADHIGFQEAYRRFYGIA
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: FGFP1_MOUSE
Sequence: MRLHSLILLSFLLLATQAFSEKVRKRAKNAPHSTAEEGVEGSAPSLGKAQNKQRSRTSKSLTHGKFVTKDQATCRWAVTEEEQGISLKVQCTQADQEFSCVFAGDPTDCLKHDKDQIYWKQVARTLRKQKNICRNAKSVLKTRVCRKRFPESNLKLVNPNARGNTKPRKEKAEVSAREHNKVQEAVSTEPNRVKEDITLNPAATQTMAIRDPECLEDPDVLNQRKTALEFCGESWSSICTFFLNMLQATSC
What is the function of this protein?
Acts as a carrier protein that releases fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhances the mitogenic activity of FGFs.  Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth (By similarity).
What are the official names of this protein?
Fibroblast growth factor-binding protein 1, FGF-BP, FGF-BP1, FGF-binding protein 1, FGFBP-1.
What is the protein family that this protein belongs to?
Belongs to the fibroblast growth factor-binding protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cell membrane; Peripheral membrane protein. Note=Extracellular and plasma membrane- associated.
Protein: TRMD_CHLMU
Sequence: MEIDILSLFPDYFTSPLQATILGRAIKQGALSIRSRDIREFGLGKWKQVDDAPYSGEGMLLMAEPVVQAIRSVKREKSKVVYLSPQGQLLSAKKSRELSLCPHLILLCGHYEGIDERALASEVDEEISIGDYVLTNGCAAALVLVDALARFIPGVLGNQESAECDSLENGLLEGPHYTRPRVFEGVQVPEILFCGDHQRIANWRKKVSLERTRERRPDLYLQYFYGDRAFWGAQEDPLKMRETSPQAFSVVLEVKDLRKAKKFYSRMFGKEHWDGDKLLLGEKTSLYLQQTNERRGATKVFVELETEDGFVRFLRRWEMLGGQLGEVGMGNLPLRQVFDLDGHIWVVSCVQK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_BRUC2
Sequence: MPDTAPQLRLYNTLTRTKEAFAPIDAKNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGAQHVTYARNITDVDDKINARAARDYPDLPFNEAIRKVTESTNAQFQADVTALGNLQPTVQPRATEHMDEMRAMIDRLVQRGVAYVAQDHVLFSPSAMNARKGPRYGALARRSLDEMLAGARVDVASYKRDEMDFVLWKPSKKGEPGWPSPAGIETLGRPGWHIECSAMSMAKLLEPFGGGLKCDDPERNQFDIHGGGIDLVFPHHENEIAQSCCALGTERMANIWMHNGFLQVEGQKMSKSLGNFITIRDVLNDGLPQLGEWGDNTVRDRWAGLAARLSMLQTHYREPINWTAQRLAESADELHRWYGLLRDEGFGAPEKLSHASAVAAALCDDLNSWAAITALRQAFKVRDVAALGEGMALMGLLDPYFVTASDVPIFARADVDASAIAARIAERLNFINAKNWAEADRIRDELLQEGVQLKDSKDPATGERITTWDVVG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_STRPC
Sequence: MKKTYRVKCEKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGISVGKKIGNAVTRNAVKRKIRHVIMALGYQLKSEDFVVIARKGVESLEYQELQQNLHHVLKLAQLLEKGFESEEKH
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PROQ_SALTI
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVERVGGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELEEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPVARRKEGAERKPRADKPTTKAPRAPREEKHTPVSDISVLTVGQSLKVKAGNNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_HYPNA
Sequence: MTVTLNLSRPNSALPGKKRLTGLSVPALKAEMEALGLEPKAANMRARQIRRWIHHFGTTDFAAMTDIAKDLRAQLAEKFEVERPEIADHQVSRDGTQKWLTRYGPGIEGESVYIPDVGKAGALCVSSQVGCTLNCTFCHTGTQALVRNLTAAEIVQQVIIARDALSEWPSSIEERRLTNIVFMGMGEPLYNLDNVAEAIDTISDGDGMAIGRRRITVSTAGVAPKIPELGERTGAMLAISLHATNNDLRNELVPLNRKYDIQTLFDAIRAYPGLGNAKRVTFEYVMLKGINDTLAEARDLVKLMKGVPSKINLIPFNPWPGSPYECSDWETIEEFAEVLNRAGYASPIRTPRGRDILAACGQLRSESVKVRASELRKQQASAEGAES
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_SHEB5
Sequence: MSIKYVATSKLPTPWGVFAMHGFEDTESGKEHVALTFGTLSADEPVLGRIHSECLTGDALFSLRCDCGFQLQAAMQNIAETGSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQLGFEADMRKYDMIKPILEQIGVKHVRLMTNNPRKVKAMKEFGIEVVERVPLQVGKNRYNEAYLKTKSTELGHMMSEYHFMDENK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: BIPA_HAEIN
Sequence: MKNEIDIKKLRNIAIIAHVDHGKTTLVDKLLQQSGTFESARGDVDERVMDSNDLEKERGITILAKNTAINWNDYRINIVDTPGHADFGGEVERVLSMVDSVLLVVDAFDGPMPQTRFVTQKAFAHGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLGASDEQLDFPIIYASALNGVAGLEHEDLAEDMTPLFEAIVKHVEPPKVELDAPFQMQISQLDYNNYVGVIGIGRIKRGSIKPNQPVTIINSEGKTRQGRIGQVLGHLGLQRYEEDVAYAGDIVAITGLGELNISDTICDINTVEALPSLTVDEPTVTMFFCVNTSPFAGQEGKYVTSRQILERLNKELVHNVALRVEETPNPDEFRVSGRGELHLSVLIENMRREGYELAVSRPKVIYRDIDGKKQEPYEQVTIDVEEQHQGSVMEALGIRKGEVRDMLPDGKGRVRLEYIIPSRGLIGFRGDFMTMTSGTGLLYSSFSHYDEIKGGEIGQRKNGVLISNATGKALGYALFGLQERGKLMIDANIEVYEGQIIGIHSRSNDLTVNCLQGKKLTNMRASGKDDAIVLTTPVKFSLEQAIEFIDDDELVEVTPESIRIRKKLLTENDRKRANRTTTSTSTH
What is the function of this protein?
A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation.  Binds GTP and analogs.  Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
What are the official names of this protein?
50S ribosomal subunit assembly factor BipA, GTP-binding protein BipA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Binds to ribosomes.
Protein: TPMT_VIBVU
Sequence: MRDAEFWHNKWASNQIGFHLEDVNPLLTRFWSALAPKREETVLVPLCGKTEDLAWLATKHDHVEGAELSLIAVRSFFAEHFYTPTVTPISGQHELYQFDELSIYAGDFFTAPLSKADLIYDRAALIALPEEMRVEYVQRIRGLLNPGGRILLVSLDYPQQEMAGPPFSVTQEEIEHLFAGMHVTRLYQDIADEHHPKIAKQGLSRFSEEVYVIENDK
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_FRATM
Sequence: MTLQQIKEIYSRPLTELILQALEIHNKNFGNDIELCSLKSIKTGTCPEDCKYCPQSGHYNTSIEKHKLLDKDSILAEAKNAKDAGSKRFCMGAAWKHIPKKDFDQVAEIITEVKNLGLETCVTLGSINADEATKLKQAGLDYYNHNLDTSREFYPEIITTRKFEERIETIRNVANADINVCCGGILGMGESLDDRFNLLLELLQLPAAPKSIPINTLIPVKGTPLGDKYTNAQIDSFELVKFIATTRILFPQARLRLSAGRENMSLETQTLCFLAGINSIFYGNKLLTENNATVNSDNFLLAKLGLKSNAELC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: LEUD_AZOPC
Sequence: MEKFVTLTSTVVPLPIQNIDTDQIIPARFLKAISKEGFGNNLFRDWRYDKNNNAISSFVLNNPIYNESKILVTGKNFGSGSSREHAAWAIADYGFKVVISSFFADIFKNNAMNNFVLPLVVSETFLSQIFESVNKNPKTTLTIDLENQIINNNSTRQLEKFIINAYKKECFLNGFDDIDFLLDKKYKIEEYERNCEY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: ZEA7_MAIZE
Sequence: MATKIFSLLMLLALSACVANATIFPQCSQAPIASLLPPYLPSMIASVCENPALQPYRLQQAIAASNIPLSPLLFQQSPALSLVQSLVQTIRAQQLQQLVLPVINQVALANLSPYSQQQQFLPFNQLSTLNPAAYLQQQLLPFSQLATAYSQQQQLLPFNQLAALNPAAYLQQQILLPFSQLAAANRASFLTQQQLLPFYQQFAANPATLLQLQQLLPFVQLALTDPAASYQQHIIGGALF
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
Zein-alpha A20, 19 kDa zein A20.
What is the protein family that this protein belongs to?
Belongs to the zein family.
Protein: NU4LM_MACOC
Sequence: MIPTYMNIMLAFTISLLGMLIYRSHLMASLLCLEGMMMSLFIMTTLIALNTRSPLTNIMPIILLVFAACEAAVGLALLVSISNTYGLDYIHNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYB_RHISA
Sequence: MLKLINPLKNLPTPSNISYMWNFGSLLGVCLLTQIITGLFLAMNFSSDISTAFSMISHIQRDVNNGWLIRSIHANGASIFFIFIYIHVARGIYYSSFFFKNVWISGILIIFALMATAFLGYILPWGQMSFWGATVITNLISAIPYIGMSVTYWIWGGFSVDNNTLIRFFTLHFLLPFILLFLVVIHITLIHEKGSSNPLGVSMNLDKIPFHPYFTIKDLLGIFVILMIFSYSIIINPYGFMDAENFNIANPMITPPHIQPEWYFLFAYAILRSIPNKLGGVIALVMSIIIILSFCFTMNNKMSSFYFNISFKLMFWILVNCFFMLTYLGAMPIEYPFDLMSKITTIIYFLMFFMIPLC
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DPOE3_HUMAN
Sequence: MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN
What is the function of this protein?
Accessory component of the DNA polymerase epsilon complex (PubMed:10801849).  Participates in DNA repair and in chromosomal DNA replication (By similarity).  Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 (PubMed:10801849).  Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (PubMed:14759371).
What are the official names of this protein?
DNA polymerase epsilon subunit 3, Arsenic-transactivated protein, AsTP, Chromatin accessibility complex 17 kDa protein, CHRAC-17, HuCHRAC17, DNA polymerase II subunit 3, DNA polymerase epsilon subunit p17.
What are the subcellular locations of this protein?
Nucleus.
Protein: HGD_STRAW
Sequence: MSGDARKTAEGLAHLTGFGNEHASEAVPGALPEGRNSPQRAPLGLYAEQLSGSAFTEPRAHNRRSWLYRIRPSAAHPPFTRADNGAIRTAPFTETAPDPNRLRWNPLPEPPAGTDFVGGLWTLGGNGDATQRTGMAVHLYHANSSMDRVFSDADGELLIVPERGGLLLRTEFGLLHAEPGQVALVPRGVRFRVDLLDESARGYVCENYGAPFQLPDLGPIGANGLAAARDFKAPVAAYEDVEGPVEVVNKFCGNLWTATYDHSPLDVVAWHGNHVPYTYDLRRFNVLGTISYDHPDPSIFTVLTSPSDTPGLAGVDFVVFAPRWLVGEDTFRPPYFHRNVMSEYMGLIEGAYDAKAAGFVPGGGSLHNMMSAHGPDRETFDRASAAELRPQKIDDGLAFMFETRWPVTATAQAARAEHLQPAYDDVWQGLQRHFRPSD
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.