PharMolix/UniProtQA huggingface dataset:
Protein: FETP_YERPY
Sequence: MSRTIFCTFLKKDAEGQDFQLYPGEIGKRIYNEISKEAWSQWITKQTMLINEKKLSMMNIEDRKLLEQEMVNFLFEGQDVHIAGYTPPSK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: SUCC_RICCN
Sequence: MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGINLVTHQTGPQGQKVNRLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGIDIEAVAEKTPDKIIKFSVDPATGLQDFHMRGIAYELGFKDNQAKQMKEIVKSVYNAFIETDATQIEINPLIVNSDGNLLALDAKITFDDNGLFRHPNITAMRDHDEEDPLETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVQGILVNIFGGIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEILSNSGLAIIPAHDLADAANKIVEAIR
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SURE_ALBFT
Sequence: MKILICNDDGYQAPGLVALYDALKDVAEVEVVAPEQNNSAKSNALTLHTPMYVCRASNGFRYINGTPADCVHIALTGLLGYRPDLVLAGINNGANMGDDTIYSGTVGAAMEGYLFGIPAIAFSQVEKNWSHLASAARKARDLVLQMSQQDLIGSSPWLLNVNIPNLTFDEIAHVKLCRLGRRHAAEAVITQVSPRGDTMYWIGAAGPAKDEAEGTDFHATSLGHIAMTPLKVDLTDHDSLGYWAQTAAKLTLA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPOT_VANPO
Sequence: MLQRIREVVSLANNPATDAVTKKQALDYLEQMKSDPNAIQIFCSMLTDSGSDDLCIFVSLQILCDLVAMNTSVDLLFVKNSIVEFLRGKINRNIKDAEFLRNKISELITRLFINMYGEVNGNQWNTFYKDLIALLSIDSLLTGPSEHFSPLGLDYFARICIQINSEVADQTFLRSKDEQTKNNNLKDTMRLEDVQTLVTIWFNCLKSLIIQQQNFELAVIILSCIGAFISWVDITLIVNPEYINIIYGYLDYSDTKIACSQCLCEIISKKMKPVDKLTLLSMLNLTDKVASIGEDDIDVYEKLAKLASSVGLELSIILEQCNEGVQSNETLEVANAADQQVLNQVAPLVLKFMSHEYDSVTEQCFPFISQYLAILKKLFAIGGKPGTAVAINSKRQPLDEAHQNFLVSLLNVCFEKMKIDDSSESNSEEAIEEFNDIVRSKLKVFQDSIAVINPNIYLENISNHIQVSLAGTDWTVLELAIFQMHNLCESIRNNLFGLNKTEISTSAATQLMHKFMALLLQNSNLFQMDNRYVQILFFELVVRHYTFLGSDTKDAVSLLNIFCSEFGMFNKSEKVILRTWYLFTRFVKISKPHLSVSVLSQLVSKVMPLLVIKTVTPSVDGSEDCDTTFDSQLYIFEGVGMLIGANADNTYDILDQVLTPLFTDLERCISLQSQSPSIVLQSHHILMAIGTLARGTHMGLVPENQVNNALVNEKLIHRTLIEKFSNIAEVVLVTFSYFNKHETIRDASRFTFARLIPILNGGIVTFASKLVVLFLESDLKTMEMNDFLGFLGQMVHTFHGDENFYDLFDNLLTPVINKLHILLDHLESESNESNWYGEQNGRENNGNDVSGARTSKTVVVTDSYRDKILLKKAYYGFLQSFVTNNVTSLLLSNRNRSILPTILGDLLSYNPQEIQETSTMKLALNVLVNFIKFFGSGGCTDVNDVHASSIGKLDGLNEYFITRTIPLAFEIPFKPQYKFNINDGSCRVIACDLSRVLKEMYIQSGGGQDVNSNPALKYLTEVYFPQIQLPSELGMELIQMLITQDTKAFEKYYVTLINRLTS
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: CH10_AGGAC
Sequence: MNIRPLHDKVILKREDVETKSAGGIVLTGSAATKSTRAKVLAVGPGRLLENGSVHPMHVKVGDTVIFSDGYGVKTEKIDGEEVLIISESDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_VANPO
Sequence: MSSVPDIKTLPKLSNPLEDAKRLAAYRAVDENVDFQNERVIGIGSGSTVVYVAERLGQYLKDPKYTKYVSQFVCIPTGFQSRALILDNGLQLDSIDHHPIIDIAFDGADEVDVNLQLIKGGGACLFQEKLVSTSAKRFIVVADHRKQSPQYLGKNWRQGVPIEVVPSAYVRVQHDLLNKLHAQTAVVRQGGSAKAGPVVTDNNNFIIDADFGEIKDPKSLYVSIEMLIGVVEVGLFIDNAEKVYFGNADGSVNVLDKKN
What are the official names of this protein?
Ribose-5-phosphate isomerase, D-ribose-5-phosphate ketol-isomerase, Phosphoriboisomerase.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI58_MOUSE
Sequence: MATAPGERLQEEARCSVCLDFLQEPISVDCGHSFCLRCISEFCEKSDSAQGVYACPQCRGPFRPASFRPNRQLASLVDSVRQLGLGTGHAGSRQCARHGEDLSHFCEEDQTMLCWVCDTSPEHRSHRTETLQEAASRYQRMLRASLELVKKEMEEALTQEANVGKKTIIWKEKVEMQRQRFRLEFEKHRGFLAQEEQLQLRRLEEEERATLQRLRDSRNRLAQQNKALKELAEELEERSQRPAPGLLEGARGVLTRCEAITRLEPEAVPMDLKTVCRIPGMREMLRKFQVDVKLDPATAHPSLLLTADLRSVQDAEVWRDVPSNPERFDTWPCILGLQGFSSGRHYWEVIVGERAEWGLGVCRDSVLRKGETTPSPENGVWAMWLLRGNEYMVLSSPSVPVLQDERPRRIGIFLDYEAGEISFYNVTNGSYIYTFNHLFSGVLRPYFFVCDTTPLILPPMTEAAPGNWTPRGIFDLAAAARNEEY
What is the function of this protein?
E3 ubiquitin ligase induced during late erythropoiesis.  Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex.  May participate in the erythroblast enucleation process through regulation of nuclear polarization.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM58, RING-type E3 ubiquitin transferase TRIM58, Tripartite motif-containing protein 58.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: C71BE_SALPM
Sequence: MEIHIPSLVLCISFFIFFKIVSKLKTKTSNRKHLPLPPGPWKLPLIGNLHNLVGALPHHTLRRLSRKFGPMMSLQLGELSAVIISSADAAKEIMKTHDLNFASRPQVAAADIIGYGSTNITFSPYGGHWRQLRKICTLELLSAKRVQSFRPLRERVFVDLCRRFADHGSSAVNFSEEFMSATYTLISRAVLGEEAEQHEGLLPNVKEMPELTAGFDISEVFPSVGLFKVMSRLRKRIVAVHKDTDRILDDVIHQHRAAKSEEHKDLLDVLLQLQEDGLELPLTDENIKSVLVDMLVAGSETSSTVIEWAMAEMLKNPRILEKAQEEVRRVFDKEGTVDESHIHELKYLKSVVKETLRVHPPAPLILPRICGETCEINGYEIPAETKIIVNAWAVNRDPKYWEDSDCFKPERFLDNLVDFRGNHFQYIPFGAGRRMCPGIGFGLANVELPLAMFMYHFDWELDGGMKPQDLDMEEKFGASAKKLKDLFLIPAIKRTLPTK
What is the function of this protein?
Monooxygenase involved in the biosynthesis of labdane-related diterpenes natural products (PubMed:26976595).  Catalyzes the oxidation of ferruginol to produce salviol (PubMed:26976595).  Salviol is an intermediate in the biosynthesis of carnosate, a potent antioxidant (PubMed:26976595).
What are the official names of this protein?
Salviol synthase, Cytochrome P450 71BE52, SpCYP71BE52.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PUP_MYCSS
Sequence: MAQEQTKRGGGGGEDDDLSGGAGAGQERREKLAEETDDLLDEIDDVLEENAEDFVRAYVQKGGQ
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation (By similarity).
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: KDPA_RHOJR
Sequence: MTPALAAGLQVAFVLAVLAVAYVPVGDYMARVYESRRHLRFESVLYRLCRINPHTEQTWYGYAGSVLGFSTASVLFLYALQRIQGVLPLSGDLSGVSPAVAFNTAVSFVTNTNWQSYAPETTMSNLTQPVGLAVQNFVSAAVGMAVAVALIRGFVRVSRGGEIGNFWVDLTRGSLRILLPFSFVIALILLSQGVIQSFHPGFASTGLDGNSVTNALAPVASQEAIKELGTNGGGILAANSAHPFENPTPVSNIVEILAILLIPVSLTRTFGTMVGDPHDRASEVSGHRQGLTLLAVMGILWGSLLAVTLAAESGRRGVAATAAGAMMEGKEVRFGIPGTALFAVSTTGTSTGAVNSAHDSLSPLGGGAVLLNMLLGEIAPGGVGTGLYGILVLALIAVFVGGLLVGRTPEYLGKKLRQREITLAALSVLVMPALVLIGTGITVILSSTTGYQGNSGDPGSPGSIHGFSEVLYAFASASNNNGSAFGGLTVTSDWFQTALGLCMLFGRFLPIIFVLALAGSLASQKKTAAGAGTLPTAGPMFTGLLTGTVVLVAALTFFPALALGPIAEALQ
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GUAB1_MYCTU
Sequence: MMRFLDGHPPGYDLTYNDVFIVPNRSEVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPIPAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVILEGRPIGLVRESSCLGVDRFTRVRDIAVTDYVTAPAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGVDVLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGADNPFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW
What is the function of this protein?
Involved in the purine-salvage pathway (PubMed:35338694).  Catalyzes the NADPH-dependent conversion of GMP to IMP (PubMed:35338694).  Has no inosine-5'-monophosphate dehydrogenase (IMPDH) activity (PubMed:21081761).
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate reductase, GMPR.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
Protein: PYRB_MARMS
Sequence: MMRSEPRALQLNEHGQLKHFLTLDGLDKTILTEILDRADSFLSMGEQSVKKVPLLRGKTVVNLFFENSTRTRTTFELAAKRLSADVINLNIETSATSKGESLLDTLKNLEAMQSDMFIVRHSDSGAAHFIAEHCTPNVAIINAGDGRHAHPTQAMLDMLTIRRHKGSFDGLKIAIVGDILHSRVARSQLQALTTLGVSDVRLVGPKTLVPSFFEEMGATICHDLEAGLKDVDVVVMLRLQKERMKGALLPSESEFYRLYGLTEETLAWAKPDAIVMHPGPINRGVEISSEVADGKHSVILNQVTNGIAVRMAVMSMAMSGQLQSDETPAAKDEK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MSRR_STAAW
Sequence: MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINPEYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKKEMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAIKDFLDED
What is the function of this protein?
Involved in SarA attenuation.  Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors (By similarity).
What are the official names of this protein?
Regulatory protein MsrR.
What is the protein family that this protein belongs to?
Belongs to the LytR/CpsA/Psr (LCP) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: MRAY_YERPG
Sequence: MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMILFSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATELVVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2743_MYCTU
Sequence: MAVKAGQRRPWRSLLQRGVDTAGDLADLVAQKISVAIDPRARLLRRRRRALRWGLVFTAGCLLWGLVTALLAAWGWFTSLLVITGTIAVTQAIPATLLLLRYRWLRSEPLPVRRPASVRRLPPPGSAARPAMSALGASERGFFSLLGVMERGAMLPADEIRDLTAAANQTSAAMVATAAEVVSMERAVQCSAASRSYLVPTINAFTAQLSTGVRQYNEMVTAAAQLVSSANGAGGAGPGQQRYREELAGATDRLVAWAQAFDELGGLPRR
What is the function of this protein?
Involved in preservation of envelope integrity and tolerance to surface stress (PubMed:25899163).  Reverses the inhibitory effect of PspA on ClgR activity (PubMed:25899163).  Facilitates intracellular growth of M. tuberculosis (PubMed:25899163).
What are the official names of this protein?
Putative envelope-preserving system protein Rv2743c.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VL2_HPV49
Sequence: MVRARRTKRDSVTNIYRTCKQAGNCPPDVVNKVEQTTIADQILKFGSTGVFFGGLGIGTGRGTGGSTGYVPIGEGPAIRVGGTPSVVRPGILPEAIGPADIIPIDTVNPIDPNASSVVPLTDTGPDLLPGTIETIAEVNPAPDIPRVDTSVVTTSRGSSAVLEVASEPTPPTRTRISRTQYHNPSFQILTESTPSLGESALTDHVVVTSGSGGQPIGGVTPVEIELQELPSRYTFEIEEPTPPRRSSTPLRNITQAVGNLRRSLYNRRLTQQVNVQDPLFLQQPSRLVRFAFDNPVFEEEVTQIFERDVAAVEEPPDRDFLDIAKLSRPLYSETPQGYVRVSRLGNRASIRTRSGATVGAQVHFYTDLSTIDAEESIELSLLGEHSGDATIVQGPVESSFVDLNVQELPQVIEVDPEPTFHSDDLLLDEQNEDFSGSQLVYGSGRRSTTFTVPRFSTPRSDTFYVQDLEGYAVSYPERRNYPEIIYPQPDLPTVIIHTADTSGDFYLHPSLRRRKRKRTYL
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: RGT1_VANPO
Sequence: MTDIAESTAHPRDGVPPSQQTTASVASAALATATASASPTTGSATSTAAPGKRSRSSSTGSAKGSIGGKKATRACDQCRKRKIKCDYDNDKNVCSSCNRNGDRCQFNRVQLKRGPSKGFNRNNSTSSAAGASTTSSTHQTFNANASGNTNSSNNNNHNNNNNNSVLLPPITQYFQGNEQNHDQQFWKVPVDLAGHLSPHHSQSHLHRDSVDSATSNNSNLNINGINIVDNSTTNSQSGGYFPVSACRSRASSVPSFPRKPPMQIQPPMTSMYASSLGGGTPATGAIGASNTAVSGATVPGTSSKRRKSVVSSNESPRTSRASLLPRPDFAVVNLVPVPQNVVTPASSLPAVPSGPLPSTGVGVGGSTGQVRLTDLDLINTYYEFVHLNFPVIPINKKALTSDILVINTSIEELNDLVIVWFRNSLELLVTVSLEQPQTQSTHAYTESLNSCFQNVVNLYPRLKQNNGIDPKVKIVYLCTFLILIYVLFFLGQHNSFIISVSVTIFNNFGLYGKLLSLNTSSPDSSSPYDIIFVRLYLLLVTFDSSYSMALGTPKLLNLEINGLVDKFFNLKSQNEHLFIDENLIKVNCILKNLELGEYICNASHMKDSSDAMKVIKSTYMSKKHQSKKADHSSSVSPMFISEWFQKFLVDKKNLISLLLDYQLRINDITPLQLSKLYVDLTNSLCALITVILEILKLMMKLNPTNSIDYNYRPLQHFDIDKPPSGGGGSSSTNTSSNPYSNPNSNEFYQKLLGLSSDRNTNLADMTRGCITPFAIITINELFNVTELIKNIPSSLISVVMESTKEEKENTINPQDLVLKLSNSMNEIVQITSLLTMVKPYKGIDSSYPRWQKFSKRSGPIPSMAPSNTATSTIQDFSEYNMTRSPSLGSSAYSNNPHSQHSDHNFNETNDYNDNISIFKKIYYENNNIQNNTTPQNEVLQSYIDTAWRLLDDSELGWL
What is the function of this protein?
Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose.  In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator.  In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription (By similarity).
What are the official names of this protein?
Glucose transport transcription regulator RGT1, Restores glucose transport protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDS1/RGT1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: VM2_CRORU
Sequence: NPCCDAATCKMRPGSQCAEGLCCDQCRFMKKGTVCRVSMVDRNDDTCTGLSADCPRNGLYG
What is the function of this protein?
Recombinant disintegrin rubistatin inhibits ADP-induced platelet aggregation.  In addition, it strongly induces apoptosis, and inhibits cell migration and proliferation of the human cancer cell line SK-Mel-28.
What are the official names of this protein?
Disintegrin rubistatin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1254_YERE8
Sequence: MFNKTLLGLTVGALMFTAGSAVAAEYKIDKEGQHAFIEFRIKHLGYSWLYGSFNDFDGSFTFDEKNPAADKVNVVINTNSVDTNHAERDKHLRSKEFLNVGKFPQATFTSTEVKKNAEGYTVVGNLTLNGVTKPVTLESKLTGQGNDPWGGYRAGFEANGNIKLKDFNITTDLGPASQEVELILSVEGVRAK
What are the official names of this protein?
UPF0312 protein YE1254.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: END8B_MYCBO
Sequence: MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTASIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYDTTDERVRYWCPACQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8 2, DNA glycosylase/AP lyase Nei 2, DNA-(apurinic or apyrimidinic site) lyase Nei 2, Endonuclease VIII 2.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL3_CLOK1
Sequence: MKKAILGKKLGMTQIFNENGRVIPVTVIEAGPCVVVQKKTEEKDGYKSIQIGFGDIREKLVNKPLKGHFAKSGVSLKRFLKEFKVDNIDEYEVGQEIKADIFAEGDRIDVSGISKGKGFQGVIRRWNAQRGPMSHGSKFHRAVGSMGASSDPSRTFKNKKMPGHMGNKNTTVLNLQVAKVIPEKNIILIKGGVPGPNKSFVSIKDTVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DTD_DESPS
Sequence: MRAVIQRSKEASVTVANNIVGEIEHGLVVFLGVQASDTEKEIKWMAEKIRHLRIFEDDEGKMNHSLQDRGGKMLIVSQFTLYGDCRKGRRPSYSQAANPEFAKRIYDLFIEEVKKSGLEVATGIFQADMDVQLINDGPVTMLLDSEKIF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_RHOPA
Sequence: MDKSKALSAALSQIERQFGKGSVMRLGKNDRSMDIETISSGSLGLDIALGVGGLPKGRIVEIYGPESSGKTTLALHCVAEAQKKGGICAFVDAEHALDPVYARKLGVNVDDLLISQPDHGEQALEIADTLVRSGAIDVLIVDSVAALVPRAELEGEMGDALPGLQARLMSQALRKLTASINKSNTMVIFINQIRMKIGVMYGSPETTTGGNALKFYASVRLDIRRIGQIKERDEVVGNQTRVKVVKNKLAPPFKQVEFDIMYGEGVSKMGEILDLGVKAGIVEKSGAWFSHDSQRLGQGRENAKAFLKANPDMTAKIEAAIRQNSGLIAEQILAGSPESDADGEEPMEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_ROSS1
Sequence: MKQSRIPRDPDGLPPLRAWLVGGGTGGHVYPALAVAAALNAHGAQFVVADTDGGRNRAMSRHTRWSALYVGSVGGMEAALVARESALPFHALPAAAVRGRNPLTMVRNLITLARGTGAAHRLIARDRPAAILGTGGYVCVPVFLAARLACVPTVIYQPDVVPGLAVRLLARLANLVACSVADSGRYLGLTPVDFERAVPQLETQNRTVRLIVTGYPVRQELFHADRRACRAVFGLSDDLPTLLVAGGSRGARSINRAIAALLPSLLPLMEIIHVCGREGDATFLRAAIRVLPENLQKRYHLFEYLHSAPDISGQEGLPSTPTMIAALVAADLAVCRSGASILGELPAVGLPAVLAPYPYVHQDENADYLVQRGAAVKVSDAALADTTEKGSLFRAIYRLLNCPEERRAMAERARALAQPDAAQKLAFLLETLVIRRQTA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y016_RICCN
Sequence: MLGLAIMAISFIFMSYSPKPELIFDANHMAVGVKDRENKLVIHADKIPAFNRTYWANWFGQKDSMVLPLENNIF
What are the official names of this protein?
Uncharacterized protein RC0016.