PharMolix/UniProtQA huggingface dataset:
Protein: LCSM_PURLI
Sequence: MCRCRHPSCITETVFPPLTWLDSEWDEICSLPVARNETHDPSGPRAPVSSMRLGPRSRPYHHGTARLRGSPNCSRDSSSAAT
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins that show extensive biological activities, including antimalarial, antiviral, antibacterial, antifungal, and antitumor activities, as well as phytotoxic (PubMed:27416025).  The function of lcsM within the leucinostatins biosynthesis has not been identified yet (Probable).
What are the official names of this protein?
Leucinostatins biosynthesis cluster protein M.
Protein: PILA3_THET2
Sequence: MKRGFTLVEVLVAMAILVVVLAVGVRYFASTSELARNTQARSELQDRVRMVMQVVTADLQMAGARYWNSGNQNQAFSLPLPPLSGSNMGPKDTLTLYYVTSLRDLASACRRVDYGFEGDTLRRSDVNATPSSGSDCTTPPPNSQPLAEGMLALDIQYQCSDGSRKDTPDCGTDAYPRSAKVTVAGYSLTSVTNPGPASLTTVTGKTLACPQGRACYALTQEVLMPNLKPLPTP
What is the function of this protein?
Plays an essential role in natural DNA transformation but is not required for pilus biogenesis.
What are the official names of this protein?
Pilin-like protein PilA3.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Cell outer membrane; Single-pass membrane protein. Periplasm. Note=The single N-terminal transmembrane is initially involved in the correct localization to the inner membrane. Once the leader sequence cleaved, this region plays a role in multimerization and protein-protein interactions in the periplasm and the outer membrane.
Protein: SAT_PSYCK
Sequence: MTSITHDQRPSKLVPPHGSAELKPLLLNGEARNQALKLASTLPAITLSSRERGDLIMFGIGGFTPLNGFMNQADWQGVVDNMRLQSGDNAGLFWPIPITLSAPKATADSLNQGDKVALVAQDGEIMGILTVEETYTIDKEHECQQVFTTTDPEHPGVQQVLEQGEVNIAGSVEVLSEGEFPTLYPEIYKTPAETRAILDNKGWQTVAAFQTRNPMHRSHEYLAKIAIEICDGVLIHSLLGALKPGDIPADVRQEAIKTLIDNYFRADTVIQAGYPLDMRYAGPREALLHAVFRQNYGCSHLIVGRDHAGVGDYYGAFDAQTIFDHVGKDDLITQPLKIGWTFWCNACNAMASDKTCPHEASEHVKVSGTKLRKALSEDLDVPENFSRPEVLQILRDYYAGIAFDERAEVKLVGASAV
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: FADI_SHEPW
Sequence: MSERQQLTNARGERIAIVSGLRTPFAKQATAFHGVSALDMGKMVVNELISRSELDPKLIEQLVYGQVVQMPAAPNIAREIVLGTGMDISTDAYSVTRACATSFQSTVNVAESILTGNMEIGIAGGSDSSSVLPIGVSKKLAHALVDLNKARSFGQKLSIFRRLGLKDLLPVPPAVAEYSTGLSMGQTAEQMAKTYNISRADQDALAHRSHTLATETWNAGKLAEEVMAAHVPPYKAFIDRDNNIRENSKLESYAKLRPAFDRKHGSVTAANSTPLTDGASAVLLMSEGRAKALGYTPIGYIKSYAFTAIDVWEDMLMGPSYATPMALKRAGMELEDLTLIEMHEAFAAQTLANMQMFGSKKFAEEKLGRNRAIGEIDMSKFNVLGGSLAYGHPFAATGTRLITQVCHELKRRGGGTGLATACAAGGLGAAMIVEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_METPP
Sequence: MRHRHGLRKLNRTSEHRLAMLRNMANSLIQSEAIKTTVPKAKELRRVVEPLITLAKEPTLANRRLAFDRTRDRDVVAKLFNDLGPRYKARPGGYTRILKMGFRVGDNAPMAFVELVDRPEPAAQAPAEATE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CH602_CHLPN
Sequence: MVWVFKSQFEGLSALKRGVHALTKAVTPAFGPRGYNVVIKKGKAPIVLTKNGIRIAKEIILQDAFESLGVKLAKEALLKVVEQTGDGSTTALVVIDALFTQGLKGIAAGLDPQEIKAGILLSVEMVYQQLQRQAIELQSPKDVLHVAMVAANHDVTLGTVVATVISQADLKGVFSSKDSGISKTRGLGKRVKSGYLSPYFVTRPETMDVVWEEALVLILSHSLVSLSEELIRYLELISEQNTHPLVIIAEDFDQNVLRTLILNKLRNGLPVCAVKAPGSRELRQVVLEDLAILTGATLIGQESENCEIPVSLDVLGRVKQVMITKETFTFLEGGGDAEIIQARKQELCLAIAGSTSESECQELEERLAIFIGSIPQVQITADTDTEQRERQFQLESALRATKAAMKGGIVPGGGVAFLRAAHAIEVPANLSSGMTFGFETLLQAVRTPLKVLAQNCGRSSEEVIHTILSHENPRFGYNGMTDTFEDLVDAGICDPLIVTTSSLKCAVSVSCLLLTSSFFISSRTKT
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_FLAJ1
Sequence: MKTNNLGYPRIGSNRELKKASELYWAGKISADELLDAGKEIRLKNWYLQSEAGVDLIPSNDFSFYDQVLDLTLAVGAIPQRYHELAKSNSSLDLYFAMARGSQKNGQDVVAMEMTKWFDTNYHYIVPEFTKNQKFELFSEKILNEFKEANAVGIKTKPVLIGPVSYLLLGKEKEEGFNRIDLIDALLPVYFEILEKLQIENAEYIQLDEPFLALNLTDKERNVFTKVYNEINVRFPKLKIVLANYFDCFGENLETALALPVDTFHLDLVRCQLQLDDILESGKLASNVNLSLGVVDGRNIWKNDFKKSLELIKKAADALGENRILLAPSCSLIHSPCDLDLETNDQTLTPEIKQWLAFAKQKINEVVLLKQFASGEVNPKNSADYERNVIANENRKTSKLIHNNEVKARTAGITAADDKRKSAFASRRKSQIKALNLPLFPTTTIGSFPQTTEVRSWRAKFKKGELTTEQYNDLIEKETEAAIRFQEETGIDVLVHGEFERNDMVEYFGEQLDGFTFTKNGWVQSYGSRCVKPPVIYGDVSRPNPMTVKWSKYAQSLTSKWVKGMLTGPVTILQWSFVRNDQPRSETCTQIALAVRDEVVDLEKAGIKIIQIDEPAIREGLPLRKEEWAKYLDWAVKAFRISASGVNDDTQIHPHMCYSEFNDIIQNIADMDADVITIECSRSQMELLDAFANFKYPNEIGPGVYDIHSPRVPSSKEMVRLLEKASAVIPVDQLWVNPDCGLKTRHWNETKKALIEMVAAAQEMRKAVENPVTE
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: Y1412_META3
Sequence: MFNSAEIIETITMIEHEHLDIRATTIGINLMDCISEDIDKLNENIYNKIVDKAGTLVKTAETVSKKYGIPIVTKRVSVTPIGSIIGSAIKNLEQEDAINCCVEVGKTLDKAAKDINIDFIGGYSALVQKGMTKGELALIESIPLMMKETSTVCSSINVASTKAGINLDAVKKMGEIIKETATTTKDALGCAKLVVFANAPEDNPFMAGAFHGVGEGDAVLNVGVSGPGVVRATVARLDNKDIGTVCNEIKKTAYKITRMGELIGREVATDLNIPFGIVDLSLAPTPAPGDSIANILEEIGLERCGTHGTTAALALLNDAVKKGGAMAASYVGGLSGSFIPVSEDAGMIRAVNDGALSIDKLEAMTCVCSVGLDMIAIPGKTPASTISAIIADEMAIGMVNKKTTAVRVIPVPGKDVGDFVEYGGLLGTAPIMPVNEYSSEEFINRGGRIPAPIQSMLN
What are the official names of this protein?
UPF0210 protein Maeo_1412.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RPN9_YEAST
Sequence: MFNNHEIDTILSTLRMEADPSLHPLFEQFEKFYEEKLWFQLSESLTKFFDDAKSTPLRLRLYDNFVSKFYDKINQLSVVKYLLASLKDSKDFDESLKYLDDLKAQFQELDSKKQRNNGSKDHGDGILLIDSEIARTYLLKNDLVKARDLLDDLEKTLDKKDSIPLRITNSFYSTNSQYFKFKNDFNSFYYTSLLYLSTLEPSTSITLAERQQLAYDLSISALLGDKIYNFGELLHHPIMETIVNDSNYDWLFQLLNALTVGDFDKFDSLIKVQISKIPILAQHESFLRQKICLMTLIETVFVKNIRMLSFEDISKATHLPKDNVEHLVMRAISLGLLKGSIDQVNELVTISWVQPRIISGDQITKMKDRLVEWNDQVEKLGKKMEARGQSIWV
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit RPN9, Proteasome non-ATPase subunit 7.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S11 family.
Protein: NCPP_YERPE
Sequence: MYHVIAATTNPAKINAITLAFDDVYGPGQYRIEGVNVDSGVPLQPIGSTETRIGARQRVKNARQVRPEADFWVGIEAGIEDNMTFAWMVVEHLQARGESRSASLMLPDIILQGIRQGRELGDEMAVLSGISNVKQQGGAIGIFTQGKLTRTSVYHQALLLALVPFHNEIYQRPSPSKPAI
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: MNTH_SALSV
Sequence: MTDNRVENSSGRAARKLRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELFFSQPDMAQLGKGMVIPALPNPEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGIADLDQAYLTLEPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFVRFHIPLWVRRTITMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSNATLMGELVNTRRVKQIGWIIVVLVVALNIWLLVGTVMGLS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNR_AQUAE
Sequence: MDKEKLEKEVIKLLSKKKKPLHFLQIAKALGLGKKERKTLKKVMRKLKKEGKVKVVKGKYEYTGEEVVTGTVIAYPGGFGFLEVEGGKDIYIPPFEMVKVFHGDVVKAKVTEFKGKKEVRIIKVLKRAKKDIVAKVVFEDEQCYVVPLDENAHHRILLSKKDCQKLKEGEVVVLKITQFPTKKSPARGKVIEVLGNPKEKFIAIDVIIRKYNLPTSYPEKVIKEVEAIPEEIPEEEIKRRRDLREQLCFTIDPEKAGDFDDAVAIELTPEGYYKLYVHIADVSYYVREGTETDKEAYKRGFTYYFPDRALHMLPEKLSAKLCSLRPNEDKLAFTVEMVFDESGNLKAYDIYESVIRSKARLTYNEALALIVGDPALEKKFPNLVEPLRMMETLYRILSRKRWEMGSIDFDLPEAEVIVDEYGEPTAIYPYERHVAHRIIEHFMISANETVALHLEHAGYPCLYRVHEPPDEEKVENLLEILEGLGYKVKRPHEYTPKFFQKIIEDFEGRPEENLVRFLTLRAMARAKYSPHNVGHFGLALEHYAHFTSPIRRYPDIIVHRLLKKALRGEEIDYEKTLAYLEEAGNHLSKQERIADEAEMEAIDYLKARYMKGRIGEEFIGIITGVVAFGFFVELEENLVEGLVKINTLTDDEYVFDEPAHRLVGVRTGKVFRLGDHVKVRCIAVDEERARVEFELIEKLEKHETL
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R, RNase R, VacB protein homolog.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRDI_CLOB6
Sequence: MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDNFENFFKYLKEKSAYLDSSRPTAVNLSWALKIMESKALENKDKDVKEIKGILREEAKRIHEEDIEICKAIGENLITLLKDGVGILTHCNAGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQDKIDAVIVGCDRIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINTKTGKDIPIEERNSEEVTSRFGVWTAPKGVKVYNPGFDVTPHENITAIVTEKGIVYPPFEENLKKLFEK
What is the function of this protein?
Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1-phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites.
What are the official names of this protein?
5-deoxyribose 1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the EIF-2B alpha/beta/delta subunits family. DrdI subfamily.
Protein: HIP1_MYCTU
Sequence: MGMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNPQVKIPGGALCGKLAVPVDYDRPDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADNDRLRAEPQVDYSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEEFPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEVYHSLVDPLVDPDNPRISRPARTKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDNRGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVTDRDKVIDEDRRAREIAPFMSYGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRGSLLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC
What is the function of this protein?
Key immunomodulatory virulence factor, which promotes survival in host macrophages and modulates host immune responses (PubMed:18172199, PubMed:21947769, PubMed:24659689).  Impacts host innate immune responses by preventing robust macrophage activation (PubMed:18172199, PubMed:21947769).  Dampens macrophage pro-inflammatory responses by limiting toll-like receptor 2 (TLR2) activation.  It also dampens TLR2-independent activation of the inflammasome and limits secretion of interleukin-18 (IL-18).  May act by masking cell surface interactions between TLR2 agonists on Mtb and TLR2 on macrophages (PubMed:21947769).  In addition, impacts host adaptive immune responses.  It prevents robust maturation of infected dendritic cells (DCs), limits the secretion of key pro-inflammatory cytokines such as IL-12, impairs Ag presentation, and modulates the nature of Ag-specific T-cell responses (PubMed:24659689).
What are the official names of this protein?
Serine protease Hip1, Hydrolase important for pathogenesis 1, Serine hydrolase Hip1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cell envelope. Cell membrane; Lipid-anchor.
Protein: MPH1_PICST
Sequence: MPIDSDDNVFDDDDDFIELLQDSSNQTSNVTNEIATDSTNSTNTRLVVPNNRLLEEIPVPKRILLGPTHHKIDYGNLDKYVYPSNFEVRDYQFNIVQRAFYHNLLVALPTGLGKTFIASTVMLNFLRWFPESKMIFVAPTKPLVAQQIKACCSITGIPSSKVAILLDKTRKNRGEIWDEKQVFFTTPQVVENDLASGLVDPKTIALLVIDEAHRAKGNYAYNNIVKFMDRFTNSYRILALTATPASDVDGVQEIIDNLNISKVEVRSEESIDIIKYMKRKRIIRRNIYQSDEIKECIDLLCTAIAPVLKVANGKGILEITDPSRINFFQCMDASRKIVANPTIPEGTKWSNFFTLQLLGVVGQCFRRLNVYGLRSFFSYFNEKYTEFMAKHSKKKSSNKLNADFYFSEPIKQLMKRIRTMIDDPKVFSHPKIEAMMEELDEFFTINNATDSKVIIFTEFRESALEIVRFIEKVGKNLKPHIFIGQAKERDKFDESNFGKKSKGKRVGKKQQDDSKSSSENAQINGMNQKLQKEIIKNFKQGTYNILVATSIGEEGLDIGEVDLIICYDSTSSPIKNIQRMGRTGRKRDGKVVLLFSSNEESKFDKAMNGYEYIQQHIMKGQLIDLKEQNRMIPKDWEPKVEMRFIEIPEENHELQVVDDEDEIIRIATQYMMGGKSKKKKAAASKKGKTKEKRAKQFFMPDNVEIGFRSVTSMVRAVGSSKSLEEEKKEEKVRDVLDRIVDSDSDEEIPLGSIPIPRSEVIAHKQSTTDEQLLERDCQSGSNISDRTLDQHHSASEERGINSNFSHESNLPTPPENSPPKRKSIVLEEARIAKKKHKKSLGIRKPTIRPPSIIDQLKKQKSKIIRPDSANETICLDEDDILLPEYTNITEKEVTVQEDRREIEHDDDSEIFDDGLDEQLAMIDDMNTTKSFVEPTRIDFKDEVFKNDFDEHEGFLNNDELMELHTSYFTAIDPMDKVFYYDPSSSVHVDGANREYAFYGKIGHSKRSQVLIGLQKRAHEMAAKSKQSKTATPSEPETFQNYLDSDFIALQ
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase MPH1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DOPD_RAT
Sequence: MPFVELETNLPASRIPAGLENRLCAATATILDKPEDRVSVTIRPGMTLLMNKSTEPCAHLLISSIGVVGTAEQNRSHSSSFFKFLTEELSLDQDRIIIRFFPLEPWQIGKKGTVMTFL
What is the function of this protein?
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
What are the official names of this protein?
D-dopachrome decarboxylase, D-dopachrome tautomerase.
What is the protein family that this protein belongs to?
Belongs to the MIF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y391_CHLTE
Sequence: MPSPDILRTEALRCVWPDGTLALDGVDLSIRAGQVTALLGSNGAGKSSLLLSFNGILKPQSGRVLLLDEPLDYSARGLKALRQKVGIVFQNPDAQLFASSVYEDISFGLCNLGLPEPETRRRIEAAMELVGVSALARKPVHHLSFGQKKRVALAGVLAMEPSVLLLDEPTAGLDPQGADAIMRFIRELQRSRGMTVVVATHDIEMAPLFCDRVCIMERGRVLFEGEISAIVEHRDLVRQAGLRLPRIAHLIEILVSKDGFTLPGNVMTIGAARKVLKTLKENQKSDERR
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein CT0391.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LPXH_YERPB
Sequence: MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS10_RHOE4
Sequence: MAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ALR_FRAT1
Sequence: MNILKISKQTLRNNIKIIREYIGNAKMCFPVKANAYGHGIEDIVENTHDLVDFFAVANSLEAFRVTAVAKNPVLVFGVIYYEYIEKMISENIRVSIQDYEDIEKLEQIAKELDKKVYAHININTGMNRMGVDYNDACRTIQRAYESDWLILEGVYSHLACADNRDHPTNIKQKNRFDSIVKFTKGLSQDIICHLSNSYGFLGQKGICYDMVRPGILSYGFLPEFYVDRVIREIKPIARLLSKVVKIITLQEGEGVGYSLIYRGFEDEQLAVIPIGYGDGFPRELGDRGFVNINDVMYPMAGRMSMDGLTVSLGINEYDVKVGDTVELISAIPRNRNSAFSIAKQTNTIEYDIMSTLNDRIIRKII
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: GAG_BLVAU
Sequence: MGNSPSYNPPAGISPSDWLNLLQSAQRLNPRPSPSDFTDLKNYIHWFHKTQKKPWTFTSGGPASCPPGKFGRVPLVLATLNEVLSNDEGAPGASAPEEQPPPYDPPAVLPIISEGNRNRHRAWALRELQDIKKEIENKAPGSQVWIQTLRLAILQADPTPADLEQLCQYIASPVDQTAHMTSLTAAIAAEAANTLQGFNPKMGTLTQQSAQPNAGDLRSQYQNLWLQAWKNLPTRPSVQPWSTIVQGPAESYVEFVNRLQISLADNLPDGVPKEPIIDSLSYANANKECQQILQGRGLVAAPVGQKLQACAHWAPKTKQPAILVHTPGPKMPGPRQPAPKRPPPGPCYRCLKEGHWARDCPTKTTGPPPGPCPICKDPSHWKRDCPTLKSKN
What is the function of this protein?
Binds strongly to viral nucleic acids and promote their aggregation.  Also destabilizes the nucleic acids duplexes via highly structured zinc-binding motifs.
What are the official names of this protein?
Gag polyprotein.
What are the subcellular locations of this protein?
[Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p12-gag]: Virion.
Protein: MHQD_BACSU
Sequence: MKHIYEKGTSDNVLLLLHGTGGNEHDLLSLGRFIDPDAHLLGVRGSVLENGMPRFFKRLSEGVFDEKDLVVRTRELKDFIDEAAETHQFNRGRVIAVGYSNGANIAASLLFHYKDVLKGAILHHPMVPIRGIELPDMAGLPVFIGAGKYDPLCTKEESEELYRYLRDSGASASVYWQDGGHQLTQHEAEQAREWYKEAIV
What is the function of this protein?
Putative hydrolase that may contribute to the degradation of aromatic compounds.
What are the official names of this protein?
Putative hydrolase MhqD.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGLO_SCYTO
Sequence: MDQGTMGYQFENWATTYSCEPELYFEPTTVEEIRQILELANQRNKRVKVVGCGHSPSDIACTDNYLVRLNKLNRILQVDKERKWITAEAGILLSDLNEKLDALGLALSNIGAVSDVALGGVIGTGTHNTGIQHGILATQIVAMTLMTAAGDTLECSNTVNREIFQATRLHLGSLGVVLNVTIQCVPAFRIHLQQFPKTLTEVLGDLDTHLKQSEYFRFFWFPHTDKVTVFYADRTNKPIKTTSSWFWNYAIGYYLLEFLLWISVFVPRLVPWINRLFYWLLYSAKAEQVKRSDKAFNFDCLFKQHVSDWALPIKQTRAALEQLKDWLDNNPNVRAHFPVEVRFVRADDILLSPCYRQDSCYINIIMYRPYGKEVPREGYWAMYEEIMKRNGGRPHWAKAHSLLRQDFEKIYPAFHKFCSIREELDPSGMFLNNYLEKTFF
What is the function of this protein?
Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate.
What are the official names of this protein?
L-gulonolactone oxidase, LGO, L-gulono-gamma-lactone oxidase, GLO.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: UPP_BURCM
Sequence: MKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVAVDAPVIAGKKLAIVPVLRAGIGMSDGLLDLVPSARVGHIGVYRAEDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAANITFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RCA_VITSX
Sequence: GLAYDISDDQQDITRMGINPIMMSAGELESGNAGEPAKMCCLFINDLDAGAGRIGVCTGIFR
What is the function of this protein?
Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4. 1. 1. 39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
What are the official names of this protein?
Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic, RA, RuBisCO activase.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO activase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CLPP_ECOUT
Sequence: MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_BACSU
Sequence: MSLLLEPSKEQIKEEKLYQQMGVSDDEFALIESILGRLPNYTEIGIFSVMWSEHCSYKNSKPILRKFPTSGERVLQGPGEGAGIVDIGDNQAVVFKIESHNHPSALEPYQGAATGVGGIIRDVFSMGARPIAVLNSLRFGELTSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDSSYEGNPLVNAMCVGLINHEDIKKGQAKGVGNTVMYVGAKTGRDGIHGATFASEEMSDSSEEKRSAVQVGDPFMEKLLLEACLEVIQCDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLIPQRETGMTAYEMMLSESQERMLLVIERGREQEIIDIFDKYDLEAVSVGHVTDDKMLRLTHKGEVVCELPVDALAEEAPVYHKPSQEPAYYREFLETDVPAPQIEDANEMLKALLQQPTIASKEWVYDQYDYMVRTNTVVAPGSDAGVLRIRGTKKALAMTTDCNARYLYLDPEVGGKIAVAEAARNIICSGAEPLAVTDNLNFGNPEKPEIFWQIEKAADGISEACNVLSTPVIGGNVSLYNESNGTAIYPTPVIGMVGLIEDTAHITTQHFKQAGDLVYVIGETKPEFAGSELQKMTEGRIYGKAPQIDLDVELSRQKALLDAIKKGFVQSAHDVSEGGLGVAIAESVMTTENLGANVTVEGEAALLFSESQSRFVVSVKKEHQAAFEATVKDAVHIGEVTADGILAIQNQDGQQMIHAQTKELERVWKGAIPCLLKSKA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.