PharMolix/UniProtQA huggingface dataset:
Protein: GCNA_MOUSE
Sequence: MDSGSSSSSSSSGSSSGSCSTSGSGSTSGSSTTSSSSSSSSSSSSSSSSSSKEYMPELPKQRKASCVVIDSESDSDNTSDEKNTTVCEISSGDETSDIDRPGGQKLPLIVIDDDDDGSPDLKNTKQKSDEPQMSVLEKEGVECIGSDSTSPHDVCEIWDVCGSSNQTSSELEPEGEPESEAKGEPESEAKGEPESEAKGEPESEAKGESESEAKGEMETEAKGESESEAKGEMETEAKGESESEAKGEMETEAKGEPESEAKGEMETEAKGEPESEAKGEMETEAKGESESEAKGEMETEAKGESESEAKGEMETEAKGEPESEAKGEMETEAKGEPESEAKGEPEPEAAKGEMETEAAMGEVETEAAMGEPEQEITAEEAKKKRAAYLLAQQRKRKRKNRFICMSSSKPRRKRRRADPQDGADPQDGADPQDRADPQDLADPQDRGDSQDMPSLPGTSDEPIPSGQPVCPRKGMASSRGRGRGRGRGRGRGRGRGRGRGRGAKAGK
What is the function of this protein?
May play a role in DNA-protein cross-links (DPCs) clearance through a SUMO-dependent recruitment to sites of DPCs, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage (PubMed:31839538).  Can resolve the topoisomerase II (TOP2A) DPCs (PubMed:31839538).
What are the official names of this protein?
Germ cell nuclear acidic protein, Acidic repeat-containing protein, Germ cell nuclear antigen.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Chromosome. Nucleus, PML body. Nucleus. Note=Co-localizes with SUMO2 at PML bodies in all interphase cells (By similarity). Localizes on condensed chromosomes in spermatocytes in G2 and M during meiotic prophase (PubMed:31839538).
Protein: PUR7_NEOSM
Sequence: MRERRKIYEGKAKILFSFPDNPNLVTQHFKDDVTAYNNRKHSVIPGKGVINNYISAFFMQNLQNVGIKTHFVKVLNMREQLVKKAELIPIEVVIRNIVAGGLAKRLGLEEGMILDAPLIETYYKSDSLGDPMVTDDHILSFNWLKLSEIEEMKVMAWRINDFLSGALSSAGIILVDLKLEFGFYDDQIILIDEISPDTCRFWDTETKEKMDKDRFRRDLGGVSKYYREVARRLGILNGSF
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: BTCC_COLOR
Sequence: MIFLLTLAGLKVLSIVILFGIIYLFASSIYNLYFHPLSRFPGPFLARAQDFWVSRQWISGNWPWEVEALHAKYGDIVRIGPNELSCAHPQSIKDIYGQPNINHPQFFRKFTTFYKQTDVGGSIGTEVDPHIHQGIRKRLAPGFSVSALSKQSDIVIRHIDSLLHQVSRNGQCQSGMNMSQWFMWLAFDVIVDLSFGEELGTVETGTGNDWINMLANSGFQIALGYVVRRRWKALQDLVRYCLVNEKSKSMRTKYIANAREKARQRLERGADVERFDFFSHLLREKAPEANIDFFASQGTTLVAAGTETTSTFMSALTYYLLQNPRALDRLQEELRRSFKHHSEIDGESTKSLKYLNAAIEEGMRIFAPAPFGLPRVSPGAMVSGEWIPKGSIIATAAHVTSRDERWFFKSKEFHPERWLPLDHPHYDHIFSKDRKDASKPFSIGSRSCIGIHLSYMEVRICVSKLAWSFDWEQVSAHEDFVKDARLLGLWKAAPFHVRYQPYPGAEPPVMNHSKINSDLA
What is the function of this protein?
Cytochrome P4590 monooxygenase part of the gene cluster that mediates the biosynthesis of betaestacins (Ref. 3).  The bifunctional terpene synthase btcA converts isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) into the sesterterpene betaestacin I (Ref. 3).  The C-terminal prenyltransferase (PT) domain of btcA catalyzes formation of GFPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GFPP into betaestacin I (Ref. 3).  The cytochrome P450 monooxygenase btcB oxidizes the C25 methyl group of betaestacin I to yield the carboxylic acid betaestacin IV via the alcohol betaestacin III (Ref. 3).  The cytochrome P450 monooxygenase btcC further catalyzes the multistep oxidation of betaestacin IV to produce several compounds, including betaestacins Va, Vb, Vc and VI (Ref. 3).
What are the official names of this protein?
Cytochrome P450 monooxygenase btcC, Betaestacins biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LEU11_CALS4
Sequence: MGVKRVIVFDTTLRDGEQTPGVNFNSRDKLEIAYQLAKLGVDVIEAGFPAASNGDFEAVKNIADYVKGVTIAAMGRAVKEDIDRASSALKNAEKSRLHVFIATSDIHLQYKLKMTRDEVLKKAVEMVKYARGKFDEIEFSAEDASRTDWDFLVKVFSEVIDAGAHIINVPDTVGYAMPREYGELIRYIRNNVPNIDGVTISAHCHNDLGLAVANSLSAIENGATQVEVTVNGIGERAGNAAMEEVIMALNTRKDYFGLVHGINTKEIYNTSKLVSELTGIKLQPNKAIVGANAFRHQSGIHQHGVINNRLTYEIMRPEDIGVVPDTFALGKLSGRNAFELKVRQLGYNLSPGEISEAFRKFKDLADRKKTIVEEDIRFVVEETIEEFRGFREGEAWA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase 1, Alpha-IPM synthase 1, Alpha-isopropylmalate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RPSD_MYCBO
Sequence: MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCRARVGTVERSGLSADDVAQEVCLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRDRAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPAKQREILILRVVVGLSAEETAAAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis.
What are the official names of this protein?
ECF RNA polymerase sigma factor SigD, ECF sigma factor SigD, Alternative RNA polymerase sigma factor SigD, RNA polymerase sigma-D factor, Sigma-D factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: RHAB_SALDC
Sequence: MTFRHCVAVDLGASSGRVMLARYDSKHRTLTLREIHRFVNCLQKTDGFDTWDIDSLEKDIRLGLKKVCNEGILIDSISIDTWGVDYVLLDKQGQRVGLPVSYRDNRTTGIMPQALVQIGKSEIYRRSGIQFLPFNTIYQLHALTKQQPELTAQVAHALLMPDYFSYRLTGEMNWEYTNATTTQLVNINTDDWDDTLLAWTGAKKSWFGRPSHPGNVIGDWICPQGNRIPVVAVASHDTASAVIASPLANKHSAYLSSGTWSLMGFESKKPYTTDEALAANITNEGGAEGRYRVLKNIMGLWLLQRVLKERRITDLPALIAQTEALPACRFLINPNDDRFINPDDMRAEIQAACRETDQPVPVSDAELARCIFDSLALLYADILHELANLRGEKFTQLHIVGGGCQNALLNQLCADACGIRVMAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSANYDLTTYIPNPDSEIARHVAQFQPKRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: PYRG_MAGSA
Sequence: MTRFIFITGGVVSSLGKGLASAALGALLQARGFKVRLRKLDPYLNVDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFTGVPSRKSDNITTGRIYSNVIAKERRGDYLGATVQVIPHVTDAIKEFVKSDLTDEDFCLCEIGGTVGDIESLPFLEAIRQLGNELGRARTMFVHLTLVPYIPSAGELKTKPTQHSVKELLSVGIQPDMLMCRCDREIPEGDRRKIALFCNVAPDAVIPALDVDSIYQVPISYHEQGMDAVVCRHFGLDAPLPDLKRWSTIVDRIRQPEGEVTIAIVGKYISLLDSYKSLAEALHHGGIANNVKVNLNWIDSQIFEQGDVVQHLEPCDGILVPGGFGERGAFGKVEAVRFARERKVPYFGICFGMQMAVIEAARNLAGYKDASSTEFGPCDNPVVGLMTEWMKGNMLEKRAASGDLGGTMRLGAYECDLKQGSRVREIYGQGRISERHRHRYEVNMGYRADLEKTGLSFSGLSPDGVLPEIVEIPDHPWFVGVQFHPELKSKPFDPHPLFTSFIAAAVRQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RL31_BACLD
Sequence: MKAGIHPEFKKATVKCACGNEFETGSVKEEVRVEICSECHPFYTGRQKFASADGRVDRFNKKYGLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SAAR1_ACRMI
Sequence: MAFVSCFHLRLLFLCLALFMAAECRPDELNKKVDSDETISDDDVSARVQPNGGKIMIVRDNDYDASDDNDNDNDDDDNNDNDNDNDDDNDVDRDNDNDDDDFDDSNDDMLSFELDSIEEKDSDGNDVGSTEGHSVESFEDRPFSLSSVDRNSNALGVAAINVNLSTKLEDSNADVDIMLYLFREDGTISFGNETFDVQAGTVKFNIKISNWDFCDGSAQDCSEAKAGEYLDVNIKFKSKDTPIEVTDEERKSQNKPAVCKDKDTPDTDSDPDDSSDNANDGDDDDDDDCPHIYNMGGDSEMLLNRGVMNGDTYTAMPFGFPKVEIEDGEKKIKFRVPKFDDNVNIDPSVTPGRVPKNASPSPALCLKIHILFIALLQAVTLFINSW
What are the official names of this protein?
Skeletal aspartic acid-rich protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_SYNP6
Sequence: MAKAKGARIVITLECTECRSNTAKRSPGVSRYTTQKNRRNTTERLEIKKFCPHCNKHTAHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MSX2_PANPA
Sequence: MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS
What is the function of this protein?
Acts as a transcriptional regulator in bone development.  Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation.  Probable morphogenetic role.  May play a role in limb-pattern formation.  In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE).  Binds to the homeodomain-response element of the ALPL promoter (By similarity).
What are the official names of this protein?
Homeobox protein MSX-2.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATB_YARLI
Sequence: MLRISRDTKIVARVTHVTKSRTYATSTAPKLVVGLEIHTQLLTKRKLFSSTTVPSLSTTPNTKVSYFDAALPGTQPRLNPQALLLALKAAIALRCDVKELTAFDRKHYFYPDQPAGYQITQHRKPLAINGKLKLNWWDLYSQNEWPALLAKEANTDSADTRDLASRSIDVPILQIQLEQDTGKSTYHGSETLVDLNRTNMPLIEIVTAPVIHTASHAAAFVKKLQTLLKRIGVSTGEFESGAMRVDVNVSIGEDGERCEIKNLPNTSSIEAAIEAEYNRQVELVGKGGTVEKSTMGFDGKKTFILRSKENAVDYRYMPDPELPLIRLSKGTLLKVRDSLPELPDKVFSRLTDDPYYVTTKDALTLIHVAGLSDYYFEVFERVSEETEDAKALKQPVNWVVNELLGRVRKADEARAAESAESGEPDLGAHDYNSIYPPAKLAELILAVHNHQLTLPSARLLFQHFLANPEDLKNMTIEQAITEFELGESGDVVDACRQVINEHESVVKSVKDGSKPGSIKFLIGMVMKATQGRINPAVIERQLKTEMRHM
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TUSC_SALAR
Sequence: MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICAASLRERGLKNVNFVVDATPLEPVALRRELGNYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDBC_PANTR
Sequence: MENGGAGTLQIRQVLLFFVLLGMSQAGSETGNFLVMEELQSGSFVGNLAKTLGLEVSELSSRGARVVSNDNKECLQLDTNTGDLLLSEMLDREELCGSNEPCVLYFQVLMKNPTQFLQIELQVRDINDHSPVFLEKEMLLEIPENSPVAAVFLLESAKDLDVGINAVKSYTINPNSHFHVKIRVNPDNRKYPELVLDKALDYEELPELSFILTALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKILENSILGSLVVTVSAWDLDSGTNSELSYTFSHASEDIRKTFEINQKSGDITLTAPLDFEAIESYSIIIQATDGGGLFGKSTVRIQVMDVNDNAPEITVSSITSPIPENTPETVVMVFRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESRAEYNITITVTDLGTPRLKTEHNITLLISDVNDNAPAFTQTSYTLFLCENNSPALHIGSISATDRDSGTNAQVTYSLLRSQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGASDHGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEMCVTGGSRSNEFKFLKPIIPNFLPQSTGSEVEENPPYQNNLGF
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-12, PCDH-beta-12.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: S35G3_RAT
Sequence: MAASHPYFNLPDFTQPSPPSTPSSLTSNHHNRCGPSNATKGLFVALLGGGLSAGFVGPFSRMAYQTSQLPSLELLIFRCLFHLPIALILKFRGDPLLGPPDVRVRAFLHAILNVLSIGCAYSAVQVVPAGNAVTVRKGSSTVCSALLALCLESQRLSGYAWCGLFGSTLGLIIIVGPGLGTLQEGTTGLYTALGYVLAFLGGLALSLGLQVYRSLHFPSCLPTVAFLFGLVGLIVSVPGLFVLQTPVLPQDTLSWSCMVAVGLLALVSFVCVSYAVTKAHPALVCAVLHSEVVVALMLQYYVLYETVAPSDIMGAGVVLGSIAIITAQNFSCDKEGQVEE
What are the official names of this protein?
Solute carrier family 35 member G3, Acyl-malonyl-condensing enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the SLC35G solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SSRP_ECO7I
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: UBC27_ARATH
Sequence: MIDFSRIQKELQDCERNQDSSGIRVCPKSDNLTRLTGTIPGPIGTPYEGGTFQIDITMPDGYPFEPPKMQFSTKVWHPNISSQSGAICLDILKDQWSPALTLKTALVSIQALLSAPEPKDPQDAVVAEQYMKNYQVFVSTARYWTETFAKKSSLEEKVKRLVEMGFGDAQVRSAIESSGGDENLALEKLCSA
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 27, E2 ubiquitin-conjugating enzyme 27, Ubiquitin carrier protein 27.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RL15_ALKCK
Sequence: MKLHELQPAEGSRKVRNRVGRGIGSGNGKTAGKGHKGQKARSGGGVRPGFEGGQNPLYRRLPKRGFTNIHRKEYTVVNLDVLNRFEAGTEVTPELLIETKTVKNVKHGIKVLGNGNLDKNLTVKAHKFSASAVKAIEAAGGKTEVV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YAJQ_SHIDS
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDARKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RL3_SALAR
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAVQVTTGVKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEYTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGGVPGATGCDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NRDR_PROM2
Sequence: MQCPTCQNTDSRVLESRSADSGKSVRRRRECLNCSFRFTTYERVESMPVSVMKKDGSRELFDKQKLFTGISRACEKTNFSSEAIINFVDGIESQIVQDSNKDIKSSQIGELILKNLRKENEVAYIRYASVYRKFNGVKDFISTLESLKGSSKNQLASIS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MURD_BACFR
Sequence: MKRIVVLGAGESGAGAAVLAKVKGFDTFVSDMSAIKDKYKTLLDGHGIAWEEGRHTEEQILSADEVVKSPGIPNDAPLILRLREQGTPIISEIEFAGRYTDAKMICITGSNGKTTTTSLIYHIFKSAGLNVGLAGNIGKSLALQVAEEKHDYYVIELSSFQLDNMYNFRADIAVLMNITPDHLDRYDHCMQNYINAKFRITQNQTSEDAFIFWNDDPIIKRELDKHGIRAHLYPFSAIKEEGSIAYVEDHEVVITEPIAFNMEQEQLALTGQHNLYNSLAAGISANLAGITKEDIRKALSDFQGVEHRLEKVARVRGIDFINDSKATNVNSCWYALQSMTTKTVLILGGKDKGNDYTEIEELVREKCSALVYLGLHNEKLHEFFDRLGLPVAEVQTGMKDAVEAAYKLAKKGETVLLSPCCASFDLFKSYEDRGEQFKKYVREL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_STRA5
Sequence: MSKQVFEMIFAGKKLVVETGQVAKQANGSVVVRYGDSTVLTAAVMSKKMSTGDFFPLQVNYEEKMYAAGKFPGGFNKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSFDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVAYVDGNFIINPTAQEQEASALELTVAGTKEAINMVESGAKELSEEIMLEALLKGHEAVCELIAFQEEIVTAIGKEKAEVELLQVDPELQAEIIATHNIALQAAVQVEEKKAREAATEAVKEVVIGEYEARYAEHEEYDRIMRDVAEILEQMEHAEVRRLITEDKIRPDGRRVDEIRPLDAEIDFLPQVHGSGLFTRGQTQALSVLTLAPMGEAQIIDGLTPEYKKRFMHHYNFPQYSVGETGRYGAAGRREIGHGALGERALEQVLPRLEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITALQMDIKIEGITPQILEEALAQAKKARFEILDVLHGAIAEPRPQLAPTAPKIDMIKIDVDKIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIFSSDQAAIDRTKDIIASLVREAKVGEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTANVADVLEIGEEVDVKVIKIDDKGRVDASMKALLPRPPKADNPKKES
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSHB_HORSE
Sequence: MKSVQFCFLFCCWKAVCCNSCELTNITIAVEKEECGFCISINTTWCAGYCYTRDLVYKDPARPNIQKTCTFKELVYETVKVPGCAHHADSLYTYPVATACHCGKCNSDSTDCTVRGLGPSYCSFGDMKE
What is the function of this protein?
Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer.  Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways.  Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
What are the official names of this protein?
Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted. Note=Efficient secretion requires dimerization with CGA.
Protein: CLPE_ECOLX
Sequence: MSKRNAVTTFFTNRVTKALGMTLALMMTCQSAMASLAADQTRYIFRGDKDALTITVTNNDKERTFGGQAWVDNIVEKDTRPTFVVTPSFFKVKPNGQQTLRIIMASDHLPKDKESVYWLNLQDIPPALEGSGIAVAVRTKLKLFYRPKALIEGRKGAEEGISLQSRPDGRTMLVNTTPYIFAIGSLLDGNGKRIATDNETAQKLLMFMPGDEVQVKGNVVKVDSLNDYGELQTWTINQKKTPTSSGQKASDSLVNPSDKADKK
What is the function of this protein?
Involved in the biogenesis of the CS31A capsule-like antigen.
What are the official names of this protein?
Chaperone protein ClpE.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DBNBT_TAXCA
Sequence: MEKAGSTDFHVKKFDPVMVAPSLPSPKATVQLSVVDSLTICRGIFNTLLVFNAPDNISADPVKIIREALSKVLVYYFPLAGRLRSKEIGELEVECTGDGALFVEAMVEDTISVLRDLDDLNPSFQQLVFWHPLDTAIEDLHLVIVQVTRFTCGGIAVGVTLPHSVCDGRGAAQFVTALAEMARGEVKPSLEPIWNRELLNPEDPLHLQLNQFDSICPPPMLEELGQASFVINVDTIEYMKQCVMEECNEFCSSFEVVAALVWIARTKALQIPHTENVKLLFAMDLRKLFNPPLPNGYYGNAIGTAYAMDNVQDLLNGSLLRAIMIIKKAKADLKDNYSRSRVVTNPYSLDVNKKSDNILALSDWRRLGFYEADFGWGGPLNVSSLQRLENGLPMFSTFLYLLPAKNKSDGIKLLLSCMPPTTLKSFKIVMEAMIEKYVSKV
What is the function of this protein?
Catalyzes the stereoselective coupling of the surrogate substrate N-debenzoyl-(3'RS)-2'-deoxytaxol with benzoyl-CoA to form predominantly one 3'-epimer of 2'-deoxytaxol (PubMed:12089320).  This enzymatic reaction constitutes the final acylation in the taxol biosynthetic pathway (PubMed:12089320).
What are the official names of this protein?
3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase, DBTNBT.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: ITPI2_PONAB
Sequence: MTTEDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSADSCDSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAIADRRKSGSQDFPQCNTIENPGTKQSTCSPGDRVTEITEVEEDLFPAETVELLREASAESDVDKSSECEFTQYTTHHILKSLASIEAKCSDMSSENTTGPPSSVDRVNTALQRAQMKVCTLSNQRMGRSLLKSKDLLKQRYLFAKVGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTPEEEQELEKRAMEHDGQSLVKSTIFISPSSVKKEEAPQSEAPRVEECHHGRTPTCSRLAPPPMSQSTCSLHSIHSEWQERPLCEHTRTLSTHSVPNISGATCSAFASPFGCPYSHRHATYPYRVCSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDPAAAPYSTQKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQLQGLRNSVRMELQDLELQLEERLLGLEEQLRAVRMPSPFRSSALMGMCGSRSADNLSCPSPLNVMEPVTELMQEQSYLKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPSHANRRTGVPSTASVGKPKTPLVARKKVFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEEAPEVVGPKSEVEEGHGKLPSMPAAEEMHKNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKASNSKQDNH
What are the official names of this protein?
Protein ITPRID2, ITPR-interacting domain-containing protein 2, Sperm-specific antigen 2 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Note=Located near the plasma membrane. Associated with actin filaments. May also exist as a membrane-bound form with extracellular regions (By similarity).
Protein: M1_I80AD
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.