PharMolix/UniProtQA huggingface dataset:
Protein: JUNB_HUMAN
Sequence: MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGPEGGGGGSYFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGATGGPPAGPGGVYAGPEPPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF
What is the function of this protein?
Transcription factor involved in regulating gene activity following the primary growth factor response.  Binds to the DNA sequence 5'-TGA[GC]TCA-3'.  Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity (By similarity).
What are the official names of this protein?
Transcription factor JunB, Transcription factor AP-1 subunit JunB.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Jun subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ILVD_XANP2
Sequence: MPQYRSRTSTHGRNMAGARGLWRATGMKDGDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEKAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGKVLLSTGEKKVDLIDAMIAAADDKVTDADVQVMERSACPTCGSCSGMFTANSMNCLTEALGLALPGNGSTLATHADRERLFVEAGHLIVDLARRYYEQDDASVLPRSVASFKAFENAMTLDISMGGSTNTVLHLLAAANEGEVPFTMADIDRLSRRVPVLCKVAPAVANIHMEDVHRAGGIMAILGELDRGGLIHTDLPTVHAATMADALDRWDVKRTKSESVATFFRAAPGGVPTQVAFSQSRRWDDLDLDRETGVIRDVAHAYSKDGGLAVLYGNIALDGCIVKTAGVDASILKFTGKARIFESQDAAVEAILSTGRIQAGDVVLIRYEGPRGGPGMQEMLYPTSYLKSKGLGKACALVTDGRFSGGSSGLSIGHVSPEAAEGGAIGLVEEGDTIEIDIPNRIIRVAVSDEVLSQRRAAMEAKGDAAWKPADRKRVVSQALQAYAALTTSAARGAVRDVSRLRR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: YQGF_CLOB6
Sequence: MRILGLDIGDRTIGIAISDPLGFTAQGITTIRRKSEAYDLEEIKKICDKYEVDTIVSGLPKNMNGTLGPQSEKVLEFCDLIKEHLNIEIKMWDERLTTVAATRAMLEADLSRSKRKKIVDKVAATYILQGYLDSLSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_SHEPC
Sequence: MAKEDNIEMQGTILETLPNTMFRVELENGHVVIAHISGKMRKNYIRILTGDKVTVQLTPYDLTKGRIVFRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTA_LACP3
Sequence: MSNIIVELKHVGKRYGDTQVLKDINIEIEQGKFYTLLGPSGSGKTTILRAIAGFLDVSEGEVLFDGKRINDVPANQRKVNTVFQDYALFPHLNVFDNVAFGLRLHRMSKQDIQTKVEDALKMVRLQGYADREISELSGGQQQRVAIARAIVLEPQVLLLDEPLSALDAKLRKDMQYELRELQERLGITFLFVTHDQEEALALSDEIFVMNDGEVQQSGTPVDIYDEPVNHFVADFIGESNIIQGHMIKDFLVEFNGKRFECADAGMRPNEPVEVVLRPEDLDITPANSGKVNVEVDTQLFRGDYYEIVGYDDLKNEWLIHSTNPAKDGETVGLTFDPEDIHVMRLNESEEDFDARLETYEGE
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LIPB_BURCM
Sequence: MSVSPVSIVSTPVAVSESPAGSPVQPAVPVTVRWRGSEAYQTSFDAMRAFTDTRTADTGDEIWVVEHPPVYTLGQAGDPAHLLVADSGVPLVKVDRGGQITYHGPGQIVVYLLLDLRRRKLMVRTLVTKIEEAVIETLAAYNLASVRKAGAPGIYVASGVHEGAKIAALGLKIRNGCSYHGLSLNVKMDLRPFLAINPCGYAGLETVDMASLEVAADWNDVAHTLVGRLIANLDGESAAADKPQALEHSND
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_PHOPR
Sequence: MPNMKTLGEFIVEKQNDFPHASGDLSSLLGSIKLAAKIVNREINKAGLVDITGAIGSENVQGEEQQKLDLYANDKFKAAMEARDQVCGVASEEEDEAVTFNKDLNRNAKYVILMDPLDGSSNIDVNVSVGTIFSIYRRVSPIGTTPTQDDFLQPGNQQVAAGYVIYGSSTMLVYTTGNGIHGFTYDPSLGVFCLSHENMQIPEDGQIYSINEGNYIRFPQGVKKYIKFCQEDVPADNRPYTSRYIGSLVSDFHRNLLKGGIYMYPSTAMYPNGKLRLLYECNPMAFLMEQAGGVASDGKNRILDITPTELHQRVPFFVGSTNMVKQVESFIEEYPEQH
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_PHYS1
Sequence: LGEFAPTRTYRGHDKKDNKKDNKKGQKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: BIOH_SALPA
Sequence: MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGYGRSSGFGAMTLEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFSAREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPDVEVLNGGLEILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIAPLLDTLWPHSTSQIMAKAAHAPFISHPAAFCQALMTLKSSL
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHE1_STAAW
Sequence: MAVQLVLNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLIELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRTKIYIHAIDFSTKEQEVESIKTSLEKIVREVGEI
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit E1, Mnh complex subunit E1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: B2L14_BOVIN
Sequence: MCTASPCDLEEIPLDDEDSDSLEFKILEFYVKHHVFQNTSAILSPKHLRTRSLSQKGPERWPVSEAWTQGPWPCRHSQSSEKAINLTKKKSSWRTLFGVAEKEEDSQSSPPEICAQAQRSGVPQARPRSPKWPRSRSSMDQRLEHKAADPRVVSIANRVAEIVYSWPPPEEVHSQGGGFKSKGVLVFQGPQGQSGAESTKKEGEDQIIARIVELLKYSGEQLERELKKDKVLMTCFQDVLSYSVVKTITDQFLRGVDTRGESEVKAQSFKAALAIDVIAKLTTIDNHPMNRVLGFGTKYLKENFSPWIQQHGGWEKILRMPHEEVD
What is the function of this protein?
Plays a role in apoptosis.
What are the official names of this protein?
Apoptosis facilitator Bcl-2-like protein 14, Bcl2-L-14.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHRN_HUMAN
Sequence: MNAPLDGLSVSSSSTGSLGSAAGAGGGGGAGLRLLSANVRQLHQALTALLSEAEREQFTHCLNAYHARRNVFDLVRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWGGPDSAGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSISPPSGLPQPHGGALRQQEGDRRSTLHLLQGGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLNILHDEAVRLLKSSRHLILTVKDVGRLPHARTTVDETKWIASSRIRETMANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMAYYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESMKARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNINALPDVSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSAPQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML
What is the function of this protein?
Involved in hearing and vision as member of the USH2 complex.  Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear.  Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear.  In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport.
What are the official names of this protein?
Whirlin, Autosomal recessive deafness type 31 protein.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, stereocilium. Cell projection, growth cone. Photoreceptor inner segment. Synapse. Note=Detected at the level of stereocilia in inner and outer hair cells of the cochlea and vestibule. Localizes to both tip and ankle-link stereocilia regions. Colocalizes with the growing ends of actin filaments. Colocalizes with MPP1 in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). In photoreceptors, localizes at a plasma membrane microdomain in the apical inner segment that surrounds the connecting cilia called periciliary membrane complex.
Protein: NADM_THEAC
Sequence: MESRKEKRAFLIGRFQPFHKGHLEIVKRILSENDSIIIGIGSAQYSHTVVNPFTAGERHLMISRTLEKERIYNYYLVPIEDVNANSLWVSHVEALTPKFDIVYTNNPLVRRLFMERKYEVRSLPMVNRKEWTGTKIREKMIAGEPWENDVPDPVVEVIHEIDGISRIRQLSTTDEDITQ
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGX_PECCP
Sequence: MAELQTGKPTPLGASFDGQGVNFALFSADAERVELCIFDERQQEQRLELTARSGDIWHGYLPAAQPGLRYGFRVDGPFEPSQGLRFNPHKLLLDPCARQLDGWVVDDDCLQGGIDQRDERDSADIMAKCVVTAEDYDWQDDQHPHTLWHQTVIYEAHVRGLTQLHPDIPEDIRGSYAALGHPVMIDYLTSLGVTALELLPVQQHADEPRLQQLGLRNYWGYNVLLPFAVDNSLAAGDDALNEFRDAVKALHRAGIEVILDVVFNHSAELDVEGPTLCQRGIDNRSYYWLGENGEYHNWTGCGNVLRLNHPAVIDWVMDCLRFWREVCHVDGFRFDLATVLGRTPDFTAAAPLLSAMKNDSRLQGCKLIAEPWDIGHGGYQLGQFPTPFAEWSDRYRDDMRRFWLHGDISLGAFARRFAASSDIFQQHDRLPFASINKLTAHDGFTLRDLVSFNHKHNDANGEGNRDGTDSNFSNNHGTEGLEADDDILQRRLASQKALLTTLILSQGTPMLLAGDELGHSQQGNNNAYCQDNELTWLHWENANSALREFVAGLIQLRRTIPALQQETWWQEGDGAVQWLNREGQPLTPQQWEQGEHQLQILLSGRWLVLFNASLHAGEFMLPEGHWQVSPPFDETNPPEGGIWHGQAQAVCVLIKQTA
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: ISPE_DEHM1
Sequence: MLTLLAPAKVNLSLEVLYRRNDGYHELRSIIQSLSLCDRLSFSPAKTVQISSDSPDWQAEHSLVSKAVALFSEKCGQGRGVNLTIAKRIPLVSGLGGDSSCAAAVLKGLNKLWGCGYPRWRLMELGAELGSDVPFFMMGGTAMMEGRGETVTPLPTLNQMWAVLLVPEIEMPPDKTAALYRNLHADSFSSGEISDKLLEDICQGKLSYSSCFNVFEKIAFTLFPDLAKYRWQFLEAGAYQIFLAGAGPTLFTLLKDKNMAEKIYHNLCQKGHQAYLVSTLGPLD
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: XTH34_POPPZ
Sequence: MAAAYPWTLFLGMLVMVSGTMGAALRKPVDVAFGRNYVPTWAFDHIKYFNGGNEIQLHLDKYTGTGFQSKGSYLFGHFSMQMKLVPGDSAGTVTAFYLSSQNSEHDEIDFEFLGNRTGQPYILQTNVFTGGKGDREQRIYLWFDPTKEFHYYSVLWNMYMIVFLVDDVPIRVFKNCKDLGVKFPFNQPMKIYSSLWNADDWATRGGLEKTDWSKAPFIASYRSFHIDGCEASVEAKFCATQGARWWDQKEFQDLDAFQYRRLSWVRQKYTIYNYCTDRSRYPSMPPECKRDRDI
What is the function of this protein?
Catalyzes xyloglucan endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers (PubMed:12595718, PubMed:15020748, PubMed:16014999, PubMed:15804235, PubMed:15125664).  Does not catalyze xyloglucan endohydrolysis (XEH) (PubMed:15804235).  Involved in early phases of secondary (S) cell wall formation in fibers of the xylem and phloem vascular tissues of wood stems.  May play a role in restructuring primary cell walls, possibly creating and reinforcing the connections between the primary and S cell wall layers (PubMed:12468728).  Functions in the gelatinous (G) layers of the tension wood fibers that are involved in bending of the wood stems.  May play a role in G fiber shrinking by repairing broken xyloglucan cross-links between G and S2 cell wall layers via its XET activity to maintain connections between the layers (PubMed:17504814).
What are the official names of this protein?
Xyloglucan endotransglucosylase protein 34, XET protein 34, PttXET16-34, PttXET16A, Xyloglucan endotransglucosylase protein 16A, XET protein 16A, Xyloglucan endotransglucosylase/hydrolase protein 34, XTH protein 34.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast. Cytoplasm. Note=Localizes to the cytoplasm of cambial cells. Localizes to the cytoplasm of xylem fibers in the early stages of secondary cell wall formation.
Protein: RLUC_SALTY
Sequence: MKTETPSVKIVAIAADEAGQRIDNFLRTQLKGVPKSMIYRILRKGEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHILVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSALRSLHEQLREKGMQKDYLALVRGQWQSHVKTVQAPLLKNILQSGERIVRVSQEGKPSETRFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDQQLTEAGTGLKRLFLHAAALKFTHPGTGEVMRIEAPMDNALKRCLQVLRNAK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase C, 23S rRNA pseudouridine(955/2504/2580) synthase, rRNA pseudouridylate synthase C, rRNA-uridine isomerase C.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: SYP_SHIDS
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIKKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRIVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH_STRGG
Sequence: MSLTAGLTDARPDTVETATVAVIGTGAIGRDLVSKIDRSPGLDCRLVAGRNPESAGLRYAESLGCATTAAGIDAVLAASPFDVVFDATSAASHRDHWPLLEPLGTLVIDLTPSKVGQMVAPTVTGVAAEDARNVNLISCGGQASVPVVHALAARFPVTYLEVVSTVASDVAGRATRLNLDEYVTATGHAVTTFSGVSDVKIILNISPAVPPATFRTVIHARVPDADAAAVRAVVDRAAEQVRSFAPGYEVVACTAADDLVTIVLKVTACSDVLPPYAGNLDIINAAAVLVAEQYAARPGRVSRTGVSS
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: GLK_STRCO
Sequence: MGLTIGVDIGGTKIAAGVVDEEGNILSTHKVPTPTTPEAIVDAIASAVEGARVGHEIVAVGIGAAGYVNRQRSTVYFAPNIDWRQEPLKEKVEARVGLPVVVENDANAAAWGEYKFGGGKGHRNVICITLGTGLGGGIIIGNKLRRGHFGVAAEFGHIRMVPDGLLCGCGSQGCWEQYASGRALVRYAKQRANATPERAEVLLALGDGTPDGIEGKHISVAARQGCPVAVDSYRELARWAGAGLADLASLFDPSAFIVGGGLSDEGDLVLDPIRKSYKRWLVGGNWRPVADVIAAQLGNKAGLVGAADLAREPDPIM
What is the function of this protein?
A probable glucose kinase (Probable).  Required for glucose repression of many different genes, restores glucose kinase activity in E. coli glk mutants (PubMed:1435260).
What are the official names of this protein?
Glucokinase, Glucose kinase, ORF 3.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSB10_HUMAN
Sequence: MERAVQGTDGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVSSRSAAAGLGGGGSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPHGTPNSASPCSQRHLSVGAPGVVTITHHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLNLLQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWAILPNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQRSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLPVYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWKAH
What is the function of this protein?
Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane.  Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable).  Plays a role in negative regulation of lipid biosynthesis (PubMed:19554302).  Negatively regulates APOB secretion from hepatocytes (PubMed:19554302, PubMed:22906437).  Binds cholesterol and acidic phospholipids (PubMed:22906437).  Also binds 25-hydroxycholesterol (PubMed:17428193).  Binds phosphatidylserine (PubMed:23934110).
What are the official names of this protein?
Oxysterol-binding protein-related protein 10, ORP-10, OSBP-related protein 10.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
Protein: DAPD_VARPS
Sequence: MTQQLQQIIDAAWEDRANISSSAAPAEVRDAVEHVISELNNGKLRVATRESVGQWTVHQWIKKAVLLSFRLKDNEQMQAGSLGFYDKVPTKFSHLSANELKESGVRIVPPAVARRGSYIAKGAILMPSYVNIGAYVGEGTMVDTWATVGSCAQIGANVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEVVEGVVIEENSVLGMGVYIGQSTPIFNRDTGETSFGRVPSGSVVISGNLPKKTKSGQEYSTYAAIIVKTVDAQTRSKTSLNDLLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_ENT38
Sequence: MSQAKTGILLANLGTPEAPTPAAVKRYLRQFLSDTRVVDTPRVLWWPLLRGVILPIRSPRVAKLYQSVWMEEGSPLMVYSRRQEKALAARLPDMPVALGMSYGKPSLESAVENLLSQDVEHIVVLALYPQYSCSTVAAVWDELARILATRRHIPGITFIRDYADDEMYIAALVNSARASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGVKHVQVMSPGFSADCLETLEEIAVQNREFFLEAGGTKYEYIPALNDSPEHIEMMVSLVTTRR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED23_AEDAE
Sequence: MSTDTQIIKLVEEILCEKTNDYDYEGPMPDEAELQKRAEDGMKKFATVFAGMSQEVKENALRSCLIHVAGINHRNKVRKHMQVLKDLVGKGIIPARLLCEQIMSSEKLVYQNQSFWIECFQVVRRVIGGVDYKGVREIMKCCKEKALSFPSGISSSILPQMLELTEVIEHIFNRNACLLPAYFIINEIQKADYQDTHWRIANLIANFIEEFVIVAQMLSIIGHSSMLPIVEHSSYADNLINPWKLDPTTLKLALRGNLPYEPELLQPQIKLLRFVLEQPYSRDMVCSMLNLQKTQKQKCMALEEQLVWLVMCAMECSEKEPVHTVDGEISSHTQWVWLHLSSQLIYFVLFQFATFQNIVNTLHDKLAVSNLRRGRDHLMWVLLQYISGSIQRNSITNFLPILKLYDSLYPEKEPLPVPDYNNPLCTHQMAPTCIWIHLLKRAQSEHYNINRSIPTALKLHHEFLQHLVMPNNNATLCMGSDYRLALLCNAYSTNPDYFSRPMAALIETILGNCKNPSAGGGSTSATQPLPTVPLSMSVLDSLTIHSKMSLIHSIVTHMIKQAQSKTTVPNTNNMAPALVETYSRLLVYTEIESLGIKGFLGQLLPQVFKSAAWGILYTLLEMFSYRMHHIQPHYRVQLLSHLHSLASVPHTNQMQLHSCVESTALRLITGLGSVEVQAQMSRYVTEQKAPGNIVSAESEELNRALILTLARSMQITGTGNDPQSTTWCKELLNSIMQNTPHTWSQHTLQCFPPVLNDLVVQHNVPKENKQLLKKSVDEEYRNWTSMSNENDIIGHFGTAGTPGTPPLFLCLLFKMIVETDTISPVAYKILERIGARALSAHLRKLCDYLVFEVSNSGDGAHVNKCVDTINDMIWKYNIITIDRLVLCLSLRTLEGNEAQVSFCIIQLLLLKTSEFRNRLQEFVSINSPEHWKQNNWHERHLAFHQKFPEKFTPDESVSHPSLPVYFGNVCLRFLPVLDITIHRYLEVPAAMSKTLDVLLDHLGPLYKFHDRPITYLYNTLHYYERMLRDRPQLKKRLVGTVIGSLKDVRPDNWAVTEQYQSYMSKKDDAVNWMPDLNYYIYLVRRMQDTIDGTNIFPGTDWRFNEFPNPPAHALYVTCVELLGLPVGPQGVANSLIDVVVKGYPVIPSQSVHNWINTIGLIMAALPESYWGVIYERLREVISCPQMTDWLHRQSPFELFNFKIVREAMLEKNYVVILAIAQSILHHSGIGQISTVTEHIKENFKPIIKTEYQLIYLCHLVGPFLNRLCAERSRAVSDITLILYELLEQVDKAQPSLALKYMDPICDLLYHIKYMFIGDMMKSDLEAIIRRLRPALQMRLRFITRLNVDEIGVDQQNVDASAAGQGPAQGGPQSQQPQTTGQAGGQPSVPQQQQQTQQQQPQQQQQVQQQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 23, Mediator complex subunit 23.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 23 family.
What are the subcellular locations of this protein?
Nucleus.