PharMolix/UniProtQA huggingface dataset:
Protein: DEF_DESHY
Sequence: MAIYQIVEIGSEVLREKAVPVKEITPNIEKLLDNMLDTLYDANGVGLAAPQVGVSKRVVVIDVGEGPIELINPVIIAKEGEDLDDEGCLSIPGITGQVARAAKVKVEALNRQGELQVIEGEGLLARCLQHEIDHLEGILFVDKAKKTQRR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: FBPB1_HAEIN
Sequence: MGWASFNLTWAWFLPVIVYGALPLLRLPQQTQAKTELFLTALSVLFMFISATVYKISMGYSVIVLLVGYTALATLSLAKLKVMQGDKFIIASLLCIILLIFFFIVYPTLAIFVSMFYDGDTFAPQQVMRILTQSYIVRVITNSLFLSGFVGIVSTVFGLAFALYTTRIARRTAFIGKIFSILPIVTPPFVVGLGVTLMLGRSGYVTEFLSTNFGFSSHNWLYGFNGIAIAQILAFAPISFMILDGALKSVHPSIEEASYTLRANRYQTFYQIIFPLLRPALANSFLIVFIQSLADFSNPLVLGGSFDVIATQIYFYIAGSQLDYASASTLGSMLLIFSLAIFIIQYIWIGNRSYVTVSGKSYRGDVQELPNGLKYTIIGMLGFWVIFNMALYGSIFYGSFTVNWGVNYTLTLKNYAMLFGQGLSDGAWPSLINTLIYAGIAAPLTAFFGLLIAYIVVRKDFQGKKSLEFLTMLCFAVPGTVAGVSYILAFNNAPLYITGTGIIVIISMVMRDLPIGMRAAIAGLGQLDKSLDEASLSLKGSSWKTLCFIVLPLLKPALLSALVTSFVRAMTTVSAIIFLVTADTRVYRIYFKSCGRRRIRHCDCIRFYFNCCDDGNYFVFRLDCRRYAYFPF
What is the function of this protein?
Part of the ABC transporter complex FbpABC (TC 3. A. 1. 10. 1) involved in Fe(3+) ions import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Putative ferric transport system permease protein FbpB 1.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FbpB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROK_THEVB
Sequence: MKLQERLGGANIYLVGMMGAGKTTTGRLLAQRLGYSFVDTDAVITAFRQRPIREIFAQEGEPAFRELEQQVLAQVSSYHHLVVATGGGIVLNPMNWSYLHHGIVVWLHVPLAVLCQRLRQDRERPLLQEQPLEERLGELLQARQHLYAQADLELRITLEDTPETVCDRLLETLPCILKPMEPC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMS1A_CARAU
Sequence: MLSTRIQCALALLSLALAVCSVSAAPTDAKLRQLLQRSLLNPAGKQELARYTLADLLSELVQAENEALEPEDLSRAVEKDEVRLELERAAGPMLAPRERKAGCKNFFWKTFTSC
What is the function of this protein?
Somatostatin inhibits the release of somatotropin.
What are the official names of this protein?
Somatostatin-1A.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_CLOK5
Sequence: MAIQAPKGTKDILPTESYKWHYLEDKFKNIADSYGYREIRTPVFEYTELFQRGVGETTDVVQKEMYTFLDRAGRSLTLKPEGTSPAVRAFVEGSLYNEAQPTKLFYFTPVLRYENVQKGRLREHHQFGIEAFGSREASLDAEVISLAMRIYEELGVDGIELNINSIGCSKCRKEYNDILKTFLSKQYDNICDTCKTRFHKNPMRILDCKEKSCREIVKDAPLMLHHLCDECREHFESLKMYLEGLGIGYKINPLIVRGLDYYSKTVFEIINKNITICGGGRYDYLIEEVGGPKMPAVGFGMGIERTLLTLSENGIEIPKLPYIDLYIGIIGDKARIKALTLTNKLREKNVRCEYDHMNRSVKAEMKYANKINARFTVILGENEIESGIAKFKRMEDGQQFEISLGDLSAILNLTRM
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAT_JEMBR
Sequence: MPGPWATTLTFPGHNGGFGGGPKCWLFWNTCAGPRRVCPKCSCPICVWHCQLCFLQKGLGIRHDGRRKKRGTRGKGRKIHYARSITESGGQRAPNCASSSASCQTWALKHGINC
What is the function of this protein?
Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication.  Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongation by the RNA polymerase II (RNA pol II) complex, thereby increasing the level of full-length transcripts.  Tat binds to a hairpin structure at the 5'-end of all nascent viral mRNAs referred to as the transactivation responsive RNA element (TAR RNA) in a CCNT1-independent mode.  Tat then recruits the CCNT1/cyclin-T1 component of the P-TEFb complex (CDK9 and CCNT1), which promotes RNA chain elongation.  The CDK9 component of P-TEFb hyperphosphorylates the C-terminus of RNA Pol II that becomes stabilized and much more processive (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein, jTat.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: VF145_ASFB7
Sequence: MDHYLKKLQDIYTKLEGHPFLFSPSKTNEKEFITLLNQALASTQLYRSIQQLFLTMYKLDPIGFINYIKTSKQEYLCLLINPKLVTKFLKITSFKIYINFRLKTFYISPNKYNNFYTAPSEEKTNHLLKEEKTWAKIVEEGGEES
What are the official names of this protein?
Uncharacterized protein K145R, pK145R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus K145R family.
What are the subcellular locations of this protein?
Virion.
Protein: RPOA_ECO57
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PGS2_HORSE
Sequence: MKATIIFLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEDRIHEVLDLEPLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKISPGAFTPLVKLERLYLSKNHLKELPEKMPKTLQELRVHENEITKVRKAVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPPGLPPSLTELHLDGNKITKVDAASLRGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLIKVPGGLADHKYIQVVYLHNNNISAVGSNDFCPPGYNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK
What is the function of this protein?
May affect the rate of fibrils formation.
What are the official names of this protein?
Decorin, Bone proteoglycan II, Dermatan sulfate proteoglycan II, DS-PGII, PG-S2.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CCOP_RUBGE
Sequence: MSDFFNSGWSLYVAGITVVSLIFCLVVLIVASRRKVMADDNTTGHVWDEDLQELNNPLPRWWAGLFLVTIAFAVIYLALYPGLGSNKGTLDWTSTGQHSAEMEKARAQMAPLYAKFVSQPAEALAKDPQAMAIGERLFANNCAQCHGADARGSKGFPNLTDNDWLHGGTHDKIKETITGGRVGNMPPMAAAVGTPEDVKNVAQYVLSLSGAPHNEVAAQLGKAKFAVCAACHGPDGKGMQAVGSANLTDKIWLHGLRRTGHHRLINNGKTNIMPAQASRLSPEQIHVLGAYVWSLSQTSTVAAR
What is the function of this protein?
C-type cytochrome.  Part of the cbb3-type cytochrome c oxidase complex.  CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit.  From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place.  The complex also functions as a proton pump (By similarity).
What are the official names of this protein?
Cbb3-type cytochrome c oxidase subunit CcoP, Cbb3-Cox subunit CcoP, C-type cytochrome CcoP, Cyt c(P), Cytochrome c oxidase subunit III.
What is the protein family that this protein belongs to?
Belongs to the CcoP / FixP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMH_SALTI
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLANELERWKQDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAT9_HUMAN
Sequence: MPIKPVGWICGQVLKNFSGRIEGIQKAIMDLVDEFKDEFPTILRLSQSNQKREPAQKTSKIRMAIALAKINRATLIRGLNSISRSSKSVAKLLHPQLACRLLELRDISGRLLREVNAPRQPLYNIQVRKGSLFEIISFPAKTALTSIIYASYAALIYLAVCVNAVLKKVKNIFQEEESIRQNREESENCRKAFSEPVLSEPMFAEGEIKAKPYRSLPEKPDISDYPKLLANKQSNNIQVLHSVFDQSAEMNEQI
What is the function of this protein?
May play a role in testicular development/spermatogenesis and may be an important factor in male infertility.
What are the official names of this protein?
Spermatogenesis-associated protein 9, Testis development protein NYD-SP16.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL32_TRIHA
Sequence: MVAAKKHVPIVKKHKTTFARHQSDRFDRVGSSWRKPKGIDGRVRRRFRGTIRMPKIGYGSNKKTRFLTPSGHNAFLHNARTLSCAAGCSMQSTDPSAAEIATPVSSRKRIASSPARQADRCSRSRRSKFRPRRLRAS
What are the official names of this protein?
60S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: SELU_PSEPF
Sequence: MSIDVTDYRDIFLNDRPLMDARAPVEFHKGAFPGAVNLPLMNDIERQRVGTCYKHHGQQAAIELGHQLVSGPVKEERIQAWAEFARTHPEGYLYCFRGGLRSQIVQQWLKSEAGVDYPRIGGGYKALRGFLIDTLESALTDCDFVLLGGMTGTGKTEVLAQLRNSVDLEGHANHRGSSFGKRATGQPSNIDFENRLAIDLLKKRAAGIDQFVLEDESRVVGSCALPLPLYQGMQQYPMVWLEDRFEQRVERILRDYVVDLSAEFQAVHGEEGFGRFCERLLESLDNVHKRLGGERHRRMRVLMEEALAEQGRSGAVELHRAWIEGLLREYYDPMYVFQREKKGGRIEFAGERQAVIEYLRQRGKSQA
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: 3L21_ACAAN
Sequence: VICYRGYNNPQTCPPGENVCFTRTWCDAFCSSRGKVVELGCAATCPIVKSYNEVKCCSTDKCNPFPVRPRRPP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Alpha-elapitoxin-Aa2b, Alpha-EPTX-Aa2b, Long neurotoxin 1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COX5A_YEAST
Sequence: MLRNTFTRAGGLSRITSVRFAQTHALSNAAVMDLQSRWENMPSTEQQDIVSKLSERQKLPWAQLTEPEKQAVWYISYGEWGPRRPVLNKGDSSFIAKGVAAGLLFSVGLFAVVRMAGGQDAKTMNKEWQLKSDEYLKSKNANPWGGYSQVQSK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TOR_ORYSJ
Sequence: MKPSPHFPEIGKKPKDLIAKEHGFNIAAYISSGADVIAAALRKHVEEEARDLSGEAFLRFMEQLYEQICSLLQSNDVAENLLALRAIDALIDMPFGEGASKVSKFANFLRTVFEVKRDPEVLVPASAVLGHLAKAGGAMTADEVERQIKTALGWLGGDRVEYRRFASVLILKEMAENASTVFNVHVPEFVDAIWVALRDPKQAVRERAVEALRACLHVIEKRETRWRVQWYYRMCEAAQVGLGKNASVHSIHGSLLAVGELLRNTGEFMMSRYREVADIVLNYLRHRDQLVRRSITSLLPRIAHFLRDRFVTNYLKICMDHILFVLRTPDERASGFVALGEMAGALGAELVPYLPLITSHLHDAIAPRRGRPSLEAISCVGSFAKAMGPAMEPHIRGGLLDAMFSAGLSDKLVEALESISTSIPSLLPTIQERLLDCISQALPKSSVRPGAAVGRGSRSSSLQQFVDSGGPVLVQLALGTLANFNFKGHELLEFARESVILYLEDEDCSTRKAAATCCCKLVAHSLSASSSSQFSSNRPNRMGGAKRRRLVEEIVEKLLMAAVADADVGVRSSVFKALYRNPSFDDFLAQADIMTSIFVALNDEEYHVRELAISVAGRLSEKNPAYVLPALRRYLIQLLTYLDQSMDSKCREESARLLGCLIRSCARLILPYIAPIHKALVARLREGTGPNANNALAAGVLATVGELAKVGGFAMRQYLPELMPLVVDALLDGGAVSKREVAVATLGQVIQSTGYVISPYNEYPPLLGLLLKLLNGELEWSTRLEVLKVLGIMGALDPHAHKRNQHKLPGQHREVLRPTMETAQHIVSMEELPTDFWPSFSASEDYYSTVAISSLMRILHDPSLSSYHQMVVGSLIFIFKSMGLGCVPYLPKVLPELFRAVRMCEDGGLKEFITWKLGTLVSIVRQHIRKYLQEILSLVSELWTSSFSLPAPNRTVQGPQASPVLHLVEQLCLALNDEFRMYILHILPSCIQVLGDAERCNDYYYVPDILHTLEVFGGNLDEHMHLVAPVLVRLFKVELVDIRRRAIVTLTKLIPTVQVGTHVSVLVHHLKLVLDGNNDDLRKDAAEALCCLAHALGEDFTIFVSSIHKLLVKHHMRYRKWDEIENRLLRREPLISENLSVQKYTQCPPEVISDPLDDFGGVPSEEADETQRQPRSHQVNDVRLRSAGEASQRSTREDWAEWMRHFSIALLKESPSPALRTCARLAQLQPSVGRELFAAGFASCWAQMNETSQEQLVRSLKTAFSSQNIPPEILATLLNLAEFMEHDEKPLPIDTRLLGALAEKCRAFAKALHYKEMEFEAVCSKKMGANPVTVVESLIHINNQLHQHEAAIGILTYSQQHLEVQLKESWYEKLHRWDEALKAYKAKSSQASGPLQNLDATLGRMRCLAALARWEDLSALCREQWTGSEPSARLEMAPMAANAAWHMGEWDHMAEYVSRLDDGDENKLRILGNTTASGDGSSNGAFFRAVLSVRCKKYEEARVYVERARRCLATELAALVLESYERAYNNMVRVQQLSELEEVIDYCTLPMESPIADSRRELIRNMWNERIKGTKRNVEVWQALLAVRELVLPPNEDRDTWIKFAKLCWKSGRISQAKSTLVKLLQFDPESSPELTLYHGHPQVVLAYLKYQYAVGDELKRRDAFCRLQDLSVQLATATNSYSGTLASQVATSNAGVPLIARVYLTLASWKRALSPGLDDDSIQEILVSYKNATLNAKDWGKAWHLWALFNTEVMSRYTLRGRPDIAGKYVVAAVTGYFYSIACASTTKGVDDSLQDILRLLTLWFNHGATSEVQMALQKGFSLVNIEMWLVVLPQIIARIHSNNKIVRELIQSLLVRIGKDHPQALMYPLLVACKSISILRQRAAQEVVDKIRQHSGGLVDQAQLVSKELIRVAILWHEMWHEALEEASRMYFGEHNIEGMLAVLEPLHAMLERGPETIKENTFIQAYGHELLEAHECCLKYRATGEDAELTKAWDLYYHVFRRIDKQLPSLTTLDLHSVSPELLECRKLELAVPGTYSADAPLVTIEYFVPQLIVITSKQRPRKLTIHGSDGNDYAFLLKGHEDLRQDERVMQLFGLVNTLLENSRKTSEKDLSIQRYAVIPLSPNSGLIGWVPNCDTLHALIREYRDARKIFLNQEHRCMLSFAPDYDHLPLIAKVEVFQHALENSEGNDLAKVLWLKSRTSEVWLERRTNYTRSLAVMSMVGYLLGLGDRHPSNLMLDRYSGKILHIDFGDCFEASMNREKFPEKVPFRLTRMLVKAMEVSGIEGTFRTTCENVMQVLRTNKDSVMAMMEAFVHDPLINWRLFNFNEVPQVTNYGNAHSHTVVNSEEAANRELMQPPRGARERELLQAVNQLGDANEVLNERAVAVMARMSHKLTGRDFSSGSSLSGAGSSTQHGNEHLASGDTREVEPGLSVKVQVQRLILQATSHENLCQNYVGWCPFW
What is the function of this protein?
Component of TORC1 complex, which is an essential cell growth regulator that controls plant development.  Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR.  Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy.
What are the official names of this protein?
Serine/threonine-protein kinase TOR, Protein TARGET OF RAPAMYCIN, OsTOR.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
Protein: YOMJ_BACSU
Sequence: MGYKFMAYGGYFLFCLFFLLMDGWRGMGICLIIVGLALLALEPYKIKAQKNIDKLKENAETLKHFDGGFNPDNFFNTYKTKIAFKESDSLVKIYQLNKDEHIEEYTIPFSNVIESEIALDNQIISKVSKSGIVAGGLLAGGIGAAIGGLSASSIQNEMVKSVTLKITVEDLGKPIHYIDFLPTQEVEGYNIQGYKKDSNVIQQALTNAEYWHGVMDVIIKKANKVAQ
What are the official names of this protein?
SPbeta prophage-derived uncharacterized membrane protein YomJ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIB3_SCHPO
Sequence: MLASIEEAVNDFRDGKFLIVLDDETRENEGDLIIAGCKVTTEQMAFLVRHSSGYVCVPMTGERLDSLEIPMMVDNNEDRMRTAYAVTLDYANGTTTGISAHDRALTTRQLANPEVTSPREFNRPGHIVPLRARDGGVLERDGHTEAAVDLCKLAGLPPVGAICELVREEDGLMSRFDDCISFGKKWGIKVITIESLKSYIKGRM
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: CHMP3_MOUSE
Sequence: MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKEVCVVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEAAEMEIDRILFEITAGALGKAPSKVTDALPEPEPAGAMAASEEGEEEEDEEDLEAMQSRLATLRS
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.  ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.  ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.  Selectively binds to phosphatidylinositol 3,5-bisphosphate PtdIns(3,5)P2 and PtdIns(3,4)P2 in preference to other phosphoinositides tested.  Involved in late stages of cytokinesis.  Plays a role in endosomal sorting/trafficking of EGF receptor (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 3, Chromatin-modifying protein 3, Vacuolar protein sorting-associated protein 24.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Lipid-anchor. Endosome. Late endosome membrane. Note=Localizes to the midbody of dividing cells.
Protein: AROB_NATTJ
Sequence: MKNKFDTLTVETGVKSKKKYPIYIGKAILNLLDKVIPRNVSVLIVIDSRIARLHRDKITRLIEFLTESRTVNQIIIPGEEDSKSLSVSESLYEKAASLNLDRSSWFIGIGGGVVGDLTGFVAATYMRGANLLHVPTTLLAQVDSSVGGKVAINQSGYKNLVGNFYQPKAVIIDTNFLDTLPIRELRAGLAEVFKYGILCDRELFLTVKSLFEDCEPLNNVSWERYSYLIHKSCEIKADIVSQDEIDTGIRMLLNLGHTFAHALEGATSYNYFKHGEAVMWGLAMSAELSYKLNKLTYKDYQAIAELPELTKVPEVPIQVKDPNIIEELLLRDKKKTGEELTVILPTSIGSAEICKCPATALIKVILES
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_CENSY
Sequence: MGQLGVGRTGKTAVLDIELRRSGSRTIISRQYSEVPLQVQRALYPDAGLPGMAHVYVLSPSGGLLQGDRYKTSISLKDKAAAHVTTQGASRIYGMNSNCAIHKMDISAGKGCYLEYIPDQVIPYAKSRYFQEVRLAIDDDAAAVYSEVVTPGRVAMGESFLYDILCTSVRCENQDGSLRFAENARAEPRRMNLRGEAVLGGYSVHGTVYVMAPPESARTIEYTAGRIISHTDGILGGTSLLPGGAGITARLLSHRTDSIFKCIEGIAGACRMEMTGAAYPGIRKC
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y293_THEAC
Sequence: MFDGEDLKKIFAMDGFLRNIEFEVSYISEGSIEIKVPLKENLMRVGDIMNGGAIMAISDAIGGLTVMTYGSVINQVTVNFNTEFIRPIGTGPVIFRSSMVRIGKNIAYVDVAAIDGNGQLCSKSMGTYYIYR
What are the official names of this protein?
Putative esterase Ta0293.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
Protein: S15A2_MOUSE
Sequence: MNPFQKNESKETLFSPVSTEEMLPGPPSPPKKSTPKLFGSSYPLSIAFIVVNEFCERFSYYGMKAVLTLYFLYFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGKMLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEEEHAEARTRYFSVFYLSINAGSLISTFITPMLRGDVKCFGEDCYALAFGIPGLLMVLALVVFAMGSKMYRKPPPEGNIVAQVTKCIWFAICNRFRNRSEDIPKRQHWLDWAAEKYPKHLIMDVKALTRILFLYIPLPMFWALLDQQGSRWTLQANKMDGDLGFFVLQPDQMQVLNPFLVLVFIPLFDLVIYRLISKCGVNFSSLRKMAVGMILACLAFAVAALVEIKINGMIHPQPASQEIFLQVLNLADGEIEVTVQGNRNNPLLVESISSFQNTTHYSKLRLETKSQDLHFHLKYNNLSVHNEYSVEEKNCYQLVVHENGESLSSMLVKDTGIKPANGMTAIRFINTLHKDMNISLDANAPLSVGKDYGVSEYRTVQRGKYPAVHCETEDNVFSLNLGQLDFGTTYLFVITNITNRGLQAWKAEDIPANKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLIVAQFSGLVQWAEFVLFSCLLLVVCLIFSVMGYYYVPLKSEGIHEATEKQIPHIQGNMINLETKNTRL
What is the function of this protein?
Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:11027540).  Transports the dipeptide-like aminopeptidase inhibitor bestatin (By similarity).  Can also transport the aminocephalosporin antibiotic cefadroxil (By similarity).  Also able to transport carnosine (By similarity).  Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs) (PubMed:29784761).  Probably acts by mediating transport of bacterial peptidoglycans across the plasma membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (PubMed:29784761).
What are the official names of this protein?
Solute carrier family 15 member 2, Kidney H(+)/peptide cotransporter, Oligopeptide transporter, kidney isoform, Peptide transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RAA2B_ARATH
Sequence: MANRIDHEYDYLFKIVLIGDSGVGKSNILSRFTRNEFCLESKSTIGVEFATRTLQVEGKTVKAQIWDTAGQERYRAITSAYYRGAVGALLVYDITKRQTFENVLRWLRELRDHADSNIVIMMAGNKSDLNHLRSVADEDGRSLAEKEGLSFLETSALEATNIEKAFQTILSEIYHIISKKALAAQEAAGNLPGQGTAINISDSSATNRKGCCST
What is the function of this protein?
Intracellular vesicle trafficking and protein transport.
What are the official names of this protein?
Ras-related protein RABA2b, AtRABA2b.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endosome membrane. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Note=During cytokinesis located to the growing margins of the cell plate.