PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_ECOLU
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMAWLRAQSASETIREYRSQAEQVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RLMN_CHLT3
Sequence: MNEVKHDIKALSLEALMALINSYGQPAFRAKQIFHWIYAHGVTDFAQMKNLSASFQTLLSQHFTVSSIQPHADTVSHEITPEQTVKFLFRLSDEQSIESVFIPSDSTSRNTLCISSQVGCAFACKFCATGYMGFIRNLTIGEILDQVLWVNRWLGDQRGGKITNVVFMGMGEPLANFDNCLAAIRILTNPDYAFQISTRKITVSTVGFIPGIQRLIDTGINCKLAISLHSAHQAIREELIPIAKEYSLATLKAILTRYNQAYKQPITFEYSLIHKINDSEQDAILLSKFCKGINCKINLIDYNSVDNIDYLPSPEGHKQAFIRKCIEHGLTVTVRKSRGADIQAACGQLAIQHVHGKKFSKIQTSRHST
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_YERPP
Sequence: MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYEGGLITPGLIDCHTHLVFGDDRSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLLEQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARRLGELLPIDVKTTCLAAHALPPEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVKLHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMANAGTVAVLLPGAYYLLRETQCPPIDLFRQYKVPMALASDANPGTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGVQQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVFRGEVRP
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_MYCGA
Sequence: MINKIMKKYETIYALATAPYNSAIHVIRLSGPDAFEIINKICDKQITKEGYRIQNARIVDNDQIIDDVLLMKFVAPKSFTGEDSIEINCHGGLFVINKIMALLNKHGAHLARRGEFSKRSYINKKIDLNQATAIHDLIFAKNNLSHSASIKALSGEFSKDIKNIQQEIFRLIGLVEIAIDYPEYEDEKKELTEEFKNLTNIRQKLQRIVNKSLKLKQISEGIKIAIVGEPNAGKSSLLNALLNEQKAIVTNIPGTTRDTVEGQIVLNDELIINLIDTAGIRKSSDQIEQIGINKSFKTIDKSDLVIYLIDLNKYQNYDKTNIYKYLINKKKQFVLVGNKVDEVDPTLNTGEIQIKISAKNNDISDLIKYLEETSLAIFNDENKQDSIFQEEWQINLLQTALYNINLILNDPNQYHDLVIQHLNEANNSLLKVLSEYEDYNLIDEIFKNFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBBL_XENLA
Sequence: MVHLSADEKSAINAVWSKVNIENDGHDALTRLLVVFPWTQRYFSSFGNLSNVAAISGNAKVRAHGKKVLSAVDESIHHLDDIKNFLSVLSTKHAEELHVDPENFKRLADVLVIVLAGKLGAAFTPQVQAAWEKFSAGLVAALSHGYF
What is the function of this protein?
This is a larval (tadpole) beta-globin.
What are the official names of this protein?
Hemoglobin larval subunit beta-1, Beta-1-globin, Hemoglobin beta-1 chain, larval.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NRDR_PSEU2
Sequence: MHCPFCGANDTKVIDSRLVAEGEQVRRRRECLACGERFTTFETAELVLPRLIKQDGSRQPFDEEKLRAGMQRALEKRPVSVERLEAALVHIKHKLRATGEREVKSLVVGELVMTELQKLDEVAYIRFASVYRRFQDLNEFREEIDRLAREPGKE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: DYP_MYCPA
Sequence: MVNIVAVRRHGVHVRVIHVPPVQPQPILAPLTPAAIFLVLTVDDGGEATVHEALQDISGLVRAIGFREPQKRLSAIASIGSDVWDRLFSGPRPAELHRFVELHGPRHTAPATPGDLLFHIRAESLDVCFELADRILKSMAGAVTVVDEVHGFRYFDNRDLLGFVDGTENPDGALAVSSTAIGDEDPDFAGSCYVHVQKYLHDMSAWTALSVTEQENVIGRTKLDDIELDDDVKPADAHIALNVITDDDGTELKIVRHNMPFGELGKSEYGTYFIGYSRTPRVTEQMLRNMFLGDPPGNTDRILDFSTAVTGGLFFSPTVDFLDDPPPLPAPGTPAAPPARNGSLSIGSLKGTTR
What is the function of this protein?
Cargo protein of a type 1 encapsulin nanocompartment.  A heme-dependent peroxidase (By similarity).  This cargo-loaded encapsulin nanocompartment is probably involved in protection against oxidative damage (By similarity).
What are the official names of this protein?
Dye-decolorizing peroxidase, DyP.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family.
What are the subcellular locations of this protein?
Encapsulin nanocompartment. Cell membrane.
Protein: CLPX_GEOKA
Sequence: MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGNEEEFEFKDVPKPLEIREILDEYVIGQDEAKKSLAVAVYNHYKRINSGSKIDDVELSKSNILMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGKKVIGFGAEMNQTDVDEKNLLSKVLPEDLLKFGLIPEFIGRLPVITTLEPLDEQALIDILTKPKNAIVKQYQKMLELDGVELEFEEAALREIAKKAIERKTGARGLRSIIEGIMLDVMFELPSREDVQKCIITLDTVRGTKPPTLIRHDGTVIELERKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SDHD_ECOSE
Sequence: MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQMHGFSAEQLRNTTHLVWATGGGMVPEEEMNQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: ADAP2_MOUSE
Sequence: MGDRERNKKRLLELLQAAGTGNGHCADCGAADPDWASYKLGIFICLHCSGVHRNFPDISKVKSVRLDFWDDSMVEFMTHHGNLNVKAKFEARVPAFYYVPQANDCLVLKEQWIRAKYERQEFTAIDKAVSHPGNREGFLWKRGRDNAQFLRRRFVLLSREGLLKYYTKEEGKAPKAVISIKDLNATFQTEKIGHPHGLQITYRKEGHTRNLFVYHDSGKEIVDWFNALRAARLQYLKLAFPDLPESELVPLITRNYLKQGFMEKTGPKHREPFKKRWFALDPQERRLLYYKNPLDAFELGQVFLGSNEQGYEVWEDLPKGIRGNRWKAGLTVITPERKFIFTCPTEKEQREWLESLRGVLSSPLSPLHLLTTSAETGCGLG
What is the function of this protein?
GTPase-activating protein for the ADP ribosylation factor family (Potential).  Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).  Possesses a stoichiometry of two binding sites for InsP4 with identical affinity (By similarity).
What are the official names of this protein?
Arf-GAP with dual PH domain-containing protein 2, Centaurin-alpha-2, Cnt-a2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Constitutively associated with the plasma membrane. Excluded from the nucleus (By similarity).
Protein: PROF1_LOKSG
Sequence: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations inhibits spontaneous rabbit actin nucleation.  This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.
What are the official names of this protein?
Loki profilin-1.
What is the protein family that this protein belongs to?
Belongs to the Asgard profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DEFB4_RAT
Sequence: MRIHYLLFSFLLVLLSPLSAFTQSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK
What is the function of this protein?
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria.  May act as a ligand for C-C chemokine receptor CCR6.  Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells.
What are the official names of this protein?
Beta-defensin 4, BD-4, BD-2, Defensin, beta 4, RBD-2, RBD-4.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PQQC_METFL
Sequence: MNAPLTDNIPWTREEFEQKLRDKGRGYHIYHPFHVMMYEGKLTREQLQCWVA
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: IHH_CHICK
Sequence: MKPARLLLLLSGCALLLAPAVRCCGPGRVVGSRRRPPRKLIPLAYKQFSPNVPEKTLGASGRYEGKIARNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGMLARLAVEAGFDWVYYESKAHIHCSVKSEHSAAAKTGGCFPGRALATLENGARTPLWALRPGQRVLAMDGAGRPTYSDFLAFLDKEPRALTAFHVIETRQPPRRLALTPTHLLFVADNASAPAAQFRPTFASHVQPGHFVLVAVGSGGLQPAEVVGVRGRTDVGAYAPLTRHGTLVVDDVVASCFALVREQQLAQMAFWPLRLYHSLLGGPGVQGDGVHWYSGLLYRLGRMLLPPDSFHPLGAPRAES
What is the function of this protein?
The dually lipidated indian hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.  Binds to the patched (PTCH1) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes (By similarity).  Plays a role in morphogenesis of the skeleton by coordinating growth and differentiation of the endochondral skeleton.  Positively regulates PTHLH expression during endochondral bone formation preventing chondrocyte hypertrophy.  In contrast, participates in normal chondrocyte proliferation in a PTHLH-independent pathway (PubMed:8662546).
What are the official names of this protein?
Indian hedgehog protein, IHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
[Indian hedgehog protein N-product]: Cell membrane; Lipid-anchor. Note=The N-product remains associated with the cell surface. SUBCELLULAR LOCATION: [Indian hedgehog protein]: Endoplasmic reticulum membrane. Golgi apparatus membrane. Secreted. Note=Co-localizes with HHAT in the ER and Golgi membrane.
Protein: YO85A_YEAST
Sequence: MRVSPSRSWSLYCSHHRQTRVSQVLAHSSSILMLQMHSGSFGNLNNDTSCRGRHHRNPNRHSYCFSNLAP
What are the official names of this protein?
Putative uncharacterized protein YOL085W-A.
Protein: MINC_BRADU
Sequence: MEAAAKVQRQMVRLRGRSYVAFVFVPTVPILDWLQEIDATIARSPGFFAGRPVVIDLSSVDLSQSGINHLLTSLQDRNIRVLGIEGVEEGRLTPMMPPLLSGGRSCVVEPSAPKKVEKAEAKPTSLLLENPVRSGQTVIFPEGDVTILGSVGSGAEVVAGGSIHVYGALRGRAMAGVNGHTSARIYCQKIEAELLAIDGFYQTADDIDAALRGKPAQAWLQGNTMRITALN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: AMPP2_PHANO
Sequence: MEVLDATSLAERLKWEAKGYWLHFEAETPLEKYPAKQHARRVQEKLGIEEGLIYLSGQQARNNEDSDMPAPFRQLRYFYYLSGGPTLAEALVKYDVDEVYYSDEVSDYIIDWYHHSCNRGKLYTLHDPAKSPIGNHHAPIDSVSLQPAMNVARMIKDEHEIKLIRKANDISSKAHREVLSNILKFTNEAQVEGLFLDVCVSHQAKQQAYDPIAASGPNAGTLHYDANDEDFGKRQLMCLDAGCEYELYASDITRTFPLSSKWPSKEAANIYRLVERMQELCIKRLAPGVRYLDLHILAHQIAIDGLLALGILHNGTKEEIYKAGTSRAFFPHGLGHHIGLEVHDVGQAELMSVRRGKQVLEQSSHLEEGMIVTVEPGIYFSVYALQHFYLPSPVHSKYINLEVLNRYLPVGGVRIEDDILITAKSYENLTTAPKGDEMLEIIQRGRSNVNSIPARRQSGRTQITEDEPPLLRAPGISASTPQSILRPIARSSTMPAELKQDKSVDFEPFEGPSLFSNFRRSMTTDEKIQRWQQDHIPTTATRINLTPSSQYKSVCGSNTREVKHVYMISGSFPPGTARGALREQILPACKQCTILCETLDRLRQSLSMSKESPEAELDVSPVISQKQIRNRRSVSSTARHDLRGDRERPQHSPMTGLANGLSAMCLEPLNHVSESPTPSQRRAGGCTPHWRGQNRADQSGDDALRAAQETQILQSKPSVRSNPATDQLSAKAVSDVLLELQRQGPAAGSDRCTLGKQEGVEGIPAISRAKNFHVSTGGSMVGEARRAEE
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase SNOG_02267, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: KHDR1_CHICK
Sequence: MQRRDDSSARMGRGPGGPGSARQGGPNPRRSPRGGGGRGAGAQHPQPLLTGGAAAGSSGAQGPAAANPAPLLPGGAVKMEPENKYLPELMAEKDSLDPSSTHAMQLLSAEIEKIQKGETTKKDEEENYLDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVPEPTRGRGGPVRGRGAAPPPPPPVPRGRGVGPPPPPPPPRGALVRGAPVRGAIARGAAVARGVPPPPAVRGAPAPRARAAGIQRIPLPPPPAPETYEEYGYDDAYADQSYEGYEGYYSQGQGDTEYYDYGHGEAQETYEAYGQDDWNGTRPSLKAPPARPVKGAYREHPYGRY
What is the function of this protein?
Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors.  Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins.  Role in G2-M progression in the cell cycle.  Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP.  Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.  Plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion.
What are the official names of this protein?
KH domain-containing, RNA-binding, signal transduction-associated protein 1, Src-associated in mitosis 68 kDa protein, Sam68.
What is the protein family that this protein belongs to?
Belongs to the KHDRBS family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Membrane. Note=Predominantly located in the nucleus but also located partially in the cytoplasm.
Protein: MATK_HYDQU
Sequence: MEEFKRYFELDRYQQHDFLYPLIFQEYIYALAHDHGLNRSIFLENAGYDNKSSLLIVKRLITRMYQQNHFLISVNDSNQNQFLGHNKNFSYQMISEGFSVIVEIPFSLRLISSLEGKXIVXYPNLRSIHSIFPFLEDKFLHLNYVLDILIPYPIHLEILVQTLRHWVKDASSLHLLRFFLHEYRNWNSLITPKKXSFSCSKRNERLSLFLYNSHVXEYESIFVFLRNQSSHXRSTSSGALLERIHFYGKIELRVGVFAKDFQSXLWLFKDPFIHYVRXQGKSILASKGTXLLMNKWKYYLVNCWXCHFYVWSQPRNIYRNQLSNYSLDFLGYLSSXRLNTSMERSQMLENSYLI
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns (By similarity).
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLPA_SHIFL
Sequence: MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor (By similarity).
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit A, G-3-P dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase.
Protein: CRL_YERPN
Sequence: MTLTSAHPKSKLMKRFAALGPYLREGQCQNDHFFFDCLAVCINVKLAPEKREFWGWWIELEPSAGRFTYVYQLGLFNKEGNWNAEKISDPEVQDKLESTLRSFHLRLEEMLASIDMKLEPAADFNDQPVKLSA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_STRTD
Sequence: MRCPKCQHNKSNVIDSRQAEDGNTIRRRRECDACHARFTTFERVEEVPLLVVKKDGTREQFSRDKIFNGISMSAQKRPVSSEDIENAITRIEKNIRRNHDGEVDSEVIGNLVMKELADLDEITYVRFASVYRSFKDVDEIEELLQEITKTVRAKKESKK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ECFA_METMP
Sequence: MAILETRDLKYSYPDGTVALNGINFKAEKGEMIAILGPNGAGKSTTFLHFNGILKPSNGSVILKGEAIKYDNKSLLNVRKTVGIVFQNPDDQLFAPTVEQDVAFGPMNLGLSKEEIEKRVKDSLKAVSMEGFERKPPHHLSGGQKKRIAIAGILAMNPEIIVLDEPTSGLDPMGASQIMKLLYELNRQGITIIISTHDVDLVPIYANKVYLLNEGKIIKGGTPREIFSDSETVRSANLRLPRVAHLIELLDKEDKLGIKMGYTIGEARNNIKEFIKGE
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA, ECF transporter A component EcfA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: COPZ_YEAST
Sequence: MSSLSLYTVQAVLILDQQGERIYAKYYQPPHRSDEGHQLLFNSVKKQKEFEKQLYRKTHKQDSEILIFEDHLVLYKEYIDITIYLVASLEENEIVLQQGFSAIRGALDLILNSGMDKKNIQENYDMVLLAIDETIDNGVILETDSNTIASRVSKPPTNEPQMALDLDKGFLGAWGFAKSKFQERLQQGL
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (PubMed:9058184).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (PubMed:9058184).
What are the official names of this protein?
Coatomer subunit zeta, Zeta-coat protein, Zeta-COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: PSBC_WELMI
Sequence: MKTLYSPRRFYPVETLFNGTLTLAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFIPEKPMYEQGLILLPHLATLGWGVGPGGEIVDTFPYFVSGILHLISSAVLGFGGIYHALIGPETLEESFPFFGYAWKDRNKMTTILGIHLILLGAGAFLLVLKALFFGGIYDTWAPGGGDVRKITNLTLSPNTIFGFLLKSPFGGEGWIVSVDNLEDIIGGHFWLGSMCIFGGIWHILTKPFAWTRRAFVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGASVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLSKLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNFVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDLEPVLFMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TATC_SYNY3
Sequence: MSTQLDNITSAETAPDYLDEVPDDVEMSLFDHLDELRTRIFLSLGAVLVGVVACFIFVKPLVQWLQVPAGTVKFLQLSPGEFFFVSVKVAGYSGILVMSPFILYQIIQFVLPGLTRRERRLLGPVVLGSSVLFFAGLGFAYYALIPAALKFFVSYGADVVEQLWSIDKYFEFVLLLMFSTGLAFQIPIIQVVLGFLGIVSSEQMLKGWRFVILGAMVLGAILTPSTDPLTQSLLAGAVLGLYFGGIGCVRLLGK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
What are the official names of this protein?
Sec-independent protein translocase protein TatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1657_NEIMA
Sequence: MFGKAGLGGLMKQAQQMQENMKKAQAKLAETEIEGEAGNGLVKITMTCAHEVRKIDISPDLIQEAADDKEMLEDLILAALKSARDKAEETANKTMGAFTQGLPPGVGDFFR
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein NMA1657.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NDK_WOLPP
Sequence: MAIERTLSILKPDAVKNNITGSINSYIEKSGLKIIAQRKMLLTKKQAELFYEIHKDRPFFGELVEFMTSGSVIVQVLIGENAVSKYRQIMGATDPKQADKGTIRGDFANDISENRVHGSDSLENAHREIAFFFAECELV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.