PharMolix/UniProtQA huggingface dataset:
Protein: PRGC2_RAT
Sequence: MAGNDCGALLDEELSSFFLNYLSDTQGGESGEEQLCADLPELDLSQLDASDFDSATCFGELQWCPETSETEPSQYSPDDSEFFQIDSENEALLAALTKTLDDIPEDDVGLAAFPGLDEGDTPSCTPASPAPLSVPPSPALERLLSPVSEVDELSLLQKLLLATSSPTASSDALKDGATWSQTSLSSRSQRPCVKVDGTQDKKTPMLRSQSRPCTELHKHLTSVLPCPRGKACSPPPHPSPQLLSKEDEEVGEDCPSPWPAPASPQDSLGQDTANPNSAQVPKDDVRAMVQLIRYMHTYCLPQRKLPQRASEPIPQSCSSPLRKVPPRSRQTPKAFWTEFSILRELLAQDILCDVSKPYRLATPVYASLTPQSRTRPPKDSQASPAHSAMAEEVRITASPKSTGPRPSLRPLRLEVKRDVNKPARQKREEDEEEEEEEEEEEEKEDEEEEWGRKRPGRGLPWTKLGRKMDSSVCPVRRSRRLNPELGPWLTFTDEPLGALPSMCLATETHDLEEELGGLTDSSQGQQLPLGSQIPTLESPCESGCGDTDEDPSCPRPPSRDSPRCLMLALSQSDPLGKKSFEESLTVELCGTAGLTPPTTPPYKPMEEDPFKQDTKHSPGQDTAPSLPSPETLQLTATPGASHKLPKRHPERSELLSHLQHATTQPVSQAGQKRPFSCSFGDHDYCQVIRPEAALQRKVLRSWEPIKVHLEDLAHQGATLPVETKTPRREADQNCDPTPKDSMQLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLLEEEEEEGGEEDDEGEDSGVSPPCSDHCPYQSPPSKASRQLCSRSRSSSGSSSCSSWSPATRKNFRLESRGPCSDGTPSARHAKKRREKAIGEGRVVYIRNLSGDMSSRELKKRFEVFGEIVECQVLRRSKRGQKHGFITFRCSEHAALSVRNGATLRKRNEPSFHLSYGGLRHFRWPRYTDYDPTSEESLPSSGKSKYEAMDFDSLLKEAQQSLH
What is the function of this protein?
Plays a role of stimulator of transcription factors and nuclear receptors activities.  Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids.  May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed.  May be part of the pathways regulating the elevation of gluconeogenesis, beta-oxidation of fatty acids and ketogenesis during fasting.  Stimulates SREBP-mediated lipogenic gene expression in the liver.  Induces energy expenditure and antagonizes obesity when overexpressed.  Induces also the expression of mitochondrial genes involved in oxidative metabolism.  Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta.
What are the subcellular locations of this protein?
Nucleus.
Protein: GRSA_BREBE
Sequence: MLNSSKSILIHAQNKNGTHEEEQYLFAVNNTKAEYPRDKTIHQLFEEQVSKRPNNVAIVCENEQLTYHELNVKANQLARIFIEKGIGKDTLVGIMMEKSIDLFIGILAVLKAGGAYVPIDIEYPKERIQYILDDSQARMLLTQKHLVHLIHNIQFNGQVEIFEEDTIKIREGTNLHVPSKSTDLAYVIYTSGTTGNPKGTMLEHKGISNLKVFFENSLNVTEKDRIGQFASISFDASVWEMFMALLTGASLYIILKDTINDFVKFEQYINQKEITVITLPPTYVVHLDPERILSIQTLITAGSATSPSLVNKWKEKVTYINAYGPTETTICATTWVATKETTGHSVPIGAPIQNTQIYIVDENLQLKSVGEAGELCIGGEGLARGYWKRPELTSQKFVDNPFVPGEKLYKTGDQARWLPDGNIEYLGRIDNQVKIRGHRVELEEVESILLKHMYISETAVSVHKDHQEQPYLCAIFVSEKHIPLEQLRQFSSEELPTYMIPSYFIQLDKMPLTSNGKIDRKQLPEPDLTFGMRVDYEAPRNEIEETLVTIWQDVLGIEKIGIKDNFYALGGDSIKAIQVAARLHSYQLKLETKDLLKYPTIDQLVHYIKDSKRRSEQGIVEGEIGLTPIQHWFFEQQFTNMHHWNQSYMLYRPNGFDKEILLRVFNKIVEHHDALRMIYKHHNGKIVQINRGLEGTLFDFYTFDLTANDNEQQVICEESARLQNSINLEVGPLVKIALFHTQNGDHLFMAIHHLVVDGISWRILFEDLATAYEQAMHQQTIALPEKTDSFKDWSIELEKYANSELFLEEAEYWHHLNYYTDNVQIKKDYVTMNNKQKNIRYVGMELTIEETEKLLKNVNKAYRTEINDILLTALGFALKEWADIDKIVINLEGHGREEILEQMNIARTVGWFTSQYPVVLDMQKSDDLSYQIKLMKENLRRIPNKGIGYEIFKYLTTEYLRPVLPFTLKPEINFNYLGQFDTDVKTELFTRSPYSMGNSLGPDGKNNLSPEGESYFVLNINGFIEEGKLHITFSYNEQQYKEDTIQQLSRSYKQHLLAIIEHCVQKEDTELTPSDFSFKELELEEMDDIFDLLADSLT
What is the function of this protein?
In the first step of peptide synthesis this enzyme activates phenylalanine and racemizes it to the D-isomer.
What are the official names of this protein?
Gramicidin S synthase 1, Gramicidin S synthase I.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PURA_PSEPG
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTEHAAAVVRYQGGHNAGHTLVINGEKTVLHLIPSGILREGVQCLIGNGVVVAPDALMREITKLEEKGVPVRERLRISPAAPLILSYHVALDQAREKARGEAKIGTTGRGIGPAYEDKVARRGLRVGDLFHRERFAAKLGELLDYHNFQLVNYYKEPAIDFQQTLDECMAYAEQLKPMMLDVTAELHNLRRAGKDIMFEGAQGSLLDIDHGTYPYVTSSNTTAGGISTGSGVGPMYLDYILGITKAYTTRVGSGPFPTELFDETGATLAKRGHEFGSTTGRARRCGWFDAVILRRAIDVNSISGICLTKLDVLDGLETINICVGYKNENGAVIDAPSDADSYIGLEPVYEEMPGWSESTLGVKTLEELPQAARDYIKRIEELVGAPIDIISTGPDRNETIVLRHPFA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTE6_ARATH
Sequence: MADSVPGHVAGGGLQGFSVDAECIKQRVDEVLQWVDSLEHKLKEVEEFYSSIGVSNSGSIGKDTEKGRHVVGIRKIQQEAARREAVAAKRMQDLMRQFGTIFRQITQHKCAWPFMHPVNVEGLGLHDYFEVIDKPMDFSTIKNQMEAKDGTGYKHVMQIYADMRLVFENAMNYNEETSDVYSMAKKLLEKFEEKWAHFLPKVQEEEKIREEEEKQAAKEALLAKEASHIKTTRELGNEICHANDELEKLMRKVVERCRKITIEEKRNIGLALLKLSPDDLQKVLGIVAQANPSFQPRAEEVSIEMDILDEPTLWRLKFFVKDALDNAMKKKKEEETKTRELSGAQKKEVSKKRNATTKLAERKTKRSRI
What is the function of this protein?
Regulates differences in leaf patterning between juvenile and mature leaves by controlling differences in the development of primordia produced during juvenile and mature phases.  Acts by activating transcription of the myb-domain protein AS1, a gene involved in leaf-axis specification.  Associates with the promoter and the start of the transcribed region of AS1 and up-regulates expression of AS1 through acetylation of histones H3 and H4.
What are the official names of this protein?
Transcription factor GTE6, Bromodomain-containing protein GTE6, Protein GENERAL TRANSCRIPTION FACTOR GROUP E6, Protein GLOBAL TRANSCRIPTION FACTOR GROUP E6.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBL_LUPDE
Sequence: SVGFKAGVKDYKLTYYTPDNQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPNAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNQIIREASKWSPELAAACEVWKE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS2_AZOCH
Sequence: MSDTLNQLAEVLEARKNAAPDSSYVASLYHKGLNKILEKVGEESVETILAAKDAAASGDCSELIYETADLWFHSLVMLAALGQHPQAVLDELERRFGLSGHAEKAARPKS
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_CHLTR
Sequence: MSDQEFGLDAIRNIGIMAHIDAGKTTTTERILFYAGRTHKIGEVHEGGATMDWMEQEQERGITITSAATTVFWLGAKINIIDTPGHVDFTIEVERSLRVLDGAVAVFDAVSGVEPQSETVWRQANKYGVPRIAFVNKMDRMGANYFGAIESMREKLGANAIPVHCPIGSESQFVGMVDLISQKTLYFLEETLGAKWEEREIPEDLQEQCATLRMQLLEELATVDESNEAFMEKVLENPDSITEEEIHTVMRKGVIEGKINPVLCGSAFKNKGVQQLLDVIVKWLPSPLDRGNVRGINLKTGEEVSLKPSKDGPLAALAFKIMTDPYVGRITFIRIYSGTLKKGSAILNSTKDKKERISRLLEMHANERTDRDEFTVGDIGACVGLKFSVTGDTLCDENQEIVLERIEAPEPVIDMAIEPKSKGDREKLAQALSALSEEDPTFRVSTNEETGQTIISGMGELHLDILRDRMIREFRVEANVGKPQVSYKETITKTSNSETKYVKQSGGRGQYAHVCLEIEPNEPGKGNEVVSKIVGGVIPKEYIPAVIKGVEEGLNSGVLAGYGLVDVKVSIVFGSYHEVDSSEMAFKICGSMAVKEACRKALPVILEPIMKVTVITPEDHLGDVIGDLNRRRGKILGQESSRNMAQVSAEVPLSEMFGYMTSLRSLTSGRATSTMEPAFFAKVPQKIQEEIVKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_PROM4
Sequence: MTEFQTLRGMVDLLPMQTQRWQIVENLARHHFHRAGLKEIRTPLLEITELFARGIGEATDVVGKEMYTFLDRGDRSCTLRPEGTASVVRSVVQHGLLNQGPQRLWYGGPMFRYERPQAGRQRQFHQMGVEFFGLPSIHADAELISIAWDLLQDLGLKDLKLELNSLGTFEDRQNYHARLNEWLECNFKLLDKDSQDRIHKNPLRILDTKNQSTQELLKDAPLLTDYLSDLSKERFLCLQEALHKLKIPFDLNHNLVRGLDYYCHTAFEITSSQLGAQATVCGGGRYDRLVKQLGGPDTPSIGWAIGMERLIILLEDSIHKEQFVDVYFINRGELPAIEALSLTRKLRAFNIIVELDHSQANFSKQFKRANRSNAKWAIIMGEDEIAKGEIRLKRLTSSINGDGFDEICFRNSEFNELVHTLKN
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_MAGMM
Sequence: MSAEAMHAAASAAPKMDPLHHFMVQKVVPIEIAGIDLSITNSTIWMWLAVAVAFLFMKWSFRGRAEDKLIPTKMQSLAEMTFTFVRQIVDQNIGGAEGRKYFPAIFTLFLLVLFCNLLGLIPGSFTPTSQLVVTATLALSVFFFATGLAIVKHGTGFIGFFVPSGVPPMLLILMVPIEIVSYLSRPVSLSVRLFANMTAGHTVLAIMFFFAATLPLGGLLMPAAFATVFTGFELFIGFIQAYIFTILTCVYINDALHLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLGA_DESAL
Sequence: MKVLIVSSELSPIAKEGGLGDAMAGLAPALDALGCEVKVAIPGYGHVLESCPGAELITENVRVSMGYFNMTADLRKVEPAPGVEAYMVCNESLFGRHGVYGDNDGLFMDNHKRYIFFSKSIPALCSASRYIPDVILANDWQTGLIPALMDQGHMPQTASVFVIHNIGYLGYVPPEDASMLGLSNTYLSYEGMEFYGQLSLLKAGIAYANKLVTVSPTYSREIQTTEQGAGLDGLMRKRSQDLAGILNGVDFQVWSPETDKHIPCNYSTADMAGKGKCKKALLDEMGMDSQLMNAPVAGMVTRLFSQKGIELVIGAVPEIVENGMGFILLGNGEESYVRDLRRLAQAYPGRFRFEEAFNEPLAHRIMAGADMLCVPSLYEPCGLTQMYALQYGTIPVARATGGLADTVRDIKAFAGKGNGFTFDAFSPGAFANAMDRAGRHYKNRKAWSALRTKAMASAGVFTWDMAAEQYYSIFERAVRARRL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: NEK9_MOUSE
Sequence: MSVLGEYERHCDSINSDFGSESGGGGDSGPGPSAVPGPRAGGGAAEQEELHYIPIRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQLVHACLDQDPEQRPAADALLDLPLLRTRRREMEEKVTLLNAPTKRPRSSTVTEAPIAVVTSRTSEVYVWGGGKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVSGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQRVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRLAMTPTERPHGSDICTSWPRPIFGSLHHVPDLSCRGWHTILIVEKVLNSKTIRSNSSGLSIGTVVQSSSPGGGIGGGGGGGGGGGGEEEDSQQESETPDPSGGFRGTMEADRGMEGLISPTEAVGNSCGASSSCPGWLRKELENAEFIPMPDSPAPLSAAFSQSEKDTLPYEELQGLKVASEVPPEPQRAAGAWPPRLDPAVPCVGKALTSAACACSALQVEVDRLQALVLKCLEEQQKLQQENLQMFTQLQKLNKKLEGGQQVGMHSRGTQTAKEEMEMDPKPDLDSESWCLLGTDSCRPSL
What is the function of this protein?
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation.  Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2.  Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues.  Important for G1/S transition and S phase progression.  Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.
What are the official names of this protein?
Serine/threonine-protein kinase Nek9, Nercc1 kinase, Never in mitosis A-related kinase 9, NimA-related protein kinase 9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSXA_ECOLI
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity).  Required to maintain the reduced state of SoxR.  Probably transfers electron from NAD(P)H to SoxR (PubMed:12773378).
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GGTA1_FELCA
Sequence: MNVKGRVVLSMLVVSTVIVVFWEYINSPEGSFLWIYHSKNPEVGDSSTQKGWWFPSWFNNRTHSYPEEEAVDEGDEQRKENSEELQLSDWFNPQKRPDVVTVTEWKAPVVWEGTYNKAILENYYARQKITVGLTVFAVGRYIEHYLEEFLISANRYFMVGHKVIFYIMVDDVSKMPLIELGPLRSFKVFEIKPEKRWQDISMMRMKIIGEHIVAHIQHEVDFLFCMDVDQVFQDSFGVETLGQSVAQLQAWWYKADPDEFTYERRKESAAYIPFGEGDFYYHAAIFGGTPTQVLNITQECFKGILQDKKNDIEAEWHDESHLNKYFLLNKPTKILSPEYCWDYHIGLPSDIKIVKISWQTKEYNLVRNNI
What is the function of this protein?
Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid.  Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isogloboside 3 (iGb3) (By similarity).
What are the official names of this protein?
N-acetyllactosaminide alpha-1,3-galactosyltransferase, UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase, Galactosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: ROGF1_ARATH
Sequence: MGSLSSEEDDEVSSERCGSYSPSADISESESSSSFSCHRFDGEGASSSIPSSPRVVAGRGFYFPAPVMLPVIGGKDVVWDDKQPDNDLSEIEMMKERFAKLLLGEDMSGGGKGVCTALAISNAITNLSATVFGELWRLEPLAPQKKAMWRRELEWLLCVSDSIVELIPSIQQFPGGGTYEIMETRPRSDLYANLPALKKLDAMLIDMLDAFSDTEFWYTDRGIVLGDCDKDSYNSPASVRQEDKWWLPCPKVPPNGLSEEARKKLQQCRDFANQILKAALAINSGVLAEMEIPDPYLETLPKSGKECLGEIIYQYLTANKFSPECLLDCLDLSSEHQTLEIANRIEAAVHVWRQKNGRRHKKQAKLKLSSWGGKVKGLVNDNERNDFLVQRAETLLQSLRIRFPGLPQTTLDMNKIQYNKDVGQSILESYSRVMESMAFNITARIDDVLYVDDAMRRSISVTESLSLFSINGLNPQKAFSVQSSPHGSPFATPALSVASRSPRRAPPLYSVKRNGTREKGIVGETEKAWSYAGNLSSRRVTGVTPERD
What is the function of this protein?
Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP.  Acts downstream of PRK2 in the control of polarized pollen tube growth by activating ARAC11/ROP1.  In association with ROPGEF4, acts as specific regulator of ARAC10/ROP11 function in ABA-mediated stomatal closure.  May play a role in the Rac/Rop-signaling pathway that controls ROS-mediated root hair development.
What are the official names of this protein?
Rop guanine nucleotide exchange factor 1, AtRopGEF1, Kinase partner protein-like, KPP-like, Rho of plants guanine nucleotide exchange factor 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Note=Localizes to the apical region of the pollen tube plasma membrane to activate ARAC11/ROP1 and interacts with ARAC10/ROP11 on plasma membrane in guard cells.
Protein: PYRD_PSYWF
Sequence: MSYALLRPFLFNLDPEHAHELTLQLLEKAHKARALGFIYSQQSLPTECMGLQFSNPVGLAAGLDKNGQYIDALAELGFGFIEVGTVTPRPQQGNEKPRLFRIKEADAIINRMGFNNLGVDRLIQNVQRAKYKGNIGINIGKNAVTPVENAADDYIYCLDRVYPHASYITVNISSPNTKNLRDLQSGEALTELLDSIKNRHSQLATEYGFYVPMVLKVAPDLTPEQVDYIANQLIEFDIDGLIATNTTLSRTGVEDLPFGDEAGGLSGRPVGHLSTQIIEQFYERLEGKVPIIGVGGIDSGDKAVRKLNAGATMIQLYSGMIYQGPKLVQQCVEAITSHRDAMML
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHL1_CAEEL
Sequence: MDEFSFPFQPYDIQLNLMREIRQCIEQRKIGIFESPTGTGKSLSVLCSTMTWLEAEELRISTDLSTRLGEVHTKITECDKITTADNWETAVREKMRAQDVETEILEQIQSRERLQSRIDQARRGMVEVSRKRKAPARDTDQFLEPQDEAAPSEEYNNDEKSEKQRDSDFFDDVDEEEEKPLKCLKIFYASRTHSQLEQLAEELAKTRFQPRIVTCASRGTLCVNEEVKKLKLNHLINEKCMELRKNGMSEKEKVQKLEKGTTKKTKTCATSCEFYNSTQIEDVVNGVLSNKLKSTLEVSKQGKLSNGCPYFATRKSVPQCQLVLLPYQVLLHDGTRKAWGIELKDNVIVLDEAHNVLNTISSLYSAEISTKSLTLALRLIREYNAHYKLKLLAHNLLYMKQLESLTSKMLIFLNSQSKEDVMTMAQLARNLNILEINLFKLAEYMEKTDLCKKFHGFYMRLQKEEIKKENEKPKLTGIQKLMAAKEAEPEPEAEPLPPPKPVPSPLFSLKSFIDALTNKCEDGRIIVEKSATEAKFRFMLLNPADRLSEVVTSARATILVGGTMEPAQLLVETLSRGSIGADSIRRFSCCHVIDDSQLLAVTVERTVDGKPFQLTYQTRGADTTLRSLATSIQALIPHIPNGVVIFVPSYDFLFNFQKKMKEFGILKRIEEKKAVFTESRQPTSDVWDRFSRAAKTSKGAILFAVVGGKMSEGINFCDELGRAVIVIGLPYPNKTSVELRERMKFLDTQMPNGGNLLYESLCMHAVNQAIGRAIRHRRDYAAVYLFDDRYAKESTRRKLSTWIGDRTQVKLGFGEIIRKTRSFFEANSKK
What is the function of this protein?
Required for normal cell proliferation and chromosome stability.  Plays a role in DNA repair during replication.
What are the official names of this protein?
ATP-dependent DNA helicase chl-1, Chromosome loss protein homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SIAT2_PANTR
Sequence: MKPHLKQWRQRMLFGLFAGGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRAIMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKSQSAFYPEDDDYFFAAGQPGWHSHSQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQRRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRGKREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTVRIINSQILTNPSHHFVDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRLNTGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS
What is the function of this protein?
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.  Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids.
What are the official names of this protein?
Beta-galactoside alpha-2,6-sialyltransferase 2, Alpha 2,6-ST 2, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2, ST6Gal II, ST6GalII, Sialyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: CWC22_MOUSE
Sequence: MKSSVAHMKSSGHNRRETHSSYRRSSSPEDRYTEQERSPRDRGYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRSRKSPSPDRSPARGGGQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEDEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFESIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKPALTSSSSESSSASDSSDSESDSSESSSESSSDASDSSSSSSTQSSTSGITAHSAKGTRKKRQGKARGEEVDKLARGHQALERRREGGREDQRHQEGRTERARSERRRAQNSRDADWRDPLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKRRERRDSFSENEKQRSRNQDSDNVRRKDRSKSRERSRRHSGHKGDDARCQNSAERRWEKPGRRPEQSRESKRSQDRRREKSPTTQK
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  Promotes exon-junction complex (EJC) assembly.  Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs.  Through its role in EJC assembly, required for nonsense-mediated mRNA decay.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC22 homolog, Nucampholin homolog.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Concentrates around speckles, which are sites of pre-mRNA synthesis and processing, where it colocalizes with EJC core proteins.
Protein: BCSY_KOMXY
Sequence: MLQLNPTPPAPGRWRTILENDFFPKNRRRDIDGLRGLAIALVVLFHAGWLKGGFIGVDVFVVISGYFMGRSALMQHPFQPVRFVCRRLYRLLPALLCMVALVSAGMLWWVLQSDRADIALNGAYALVYLSNIWASGHVGYFQGQAVAYPFLHTWSLSLEMQFYAIIFIMALLLPLTRHRRLVLSAIFSASAAYCAYAWHTGDSQAYYNILDRLWQFALGTMVWMLPRPKLPRAAADAVYAAAVAVIVGAGLFYPLSYACPSWMTVFPCGAVVLIIMLPDTRVGRWCLVPLSPLGVISYSVYLWHWPGIVVANYLLFFQVHGAMMAGVLALVMVVSLLSYVLVERTGLDYENRAPVAARNRGAALLVAACLGLAAVLAYISHVSRVH
What is the function of this protein?
May acylate a glucose moiety into cellulose fibrils, in cooperation with BcsABII and BcsCII.
What are the official names of this protein?
Putative membrane-bound transacylase BcsY.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METK_NITOC
Sequence: MKEIRQFTSESVSEGHPDKVADQISDVILDAILAQDRRARVACETLVKTGMVLVAGEITTQAHIDYEQIIRETITEIGYNHSEIGFDGATCAVVNAIGKQSSDIAQGVDRELEEDQGAGDQGMMFGYASDETDVLMPAPITYAHRLVQRQAEIRRNGELPWLRPDAKSQVTLLYEDDVPVAIDAIVLSTQHSPEISQATLREAVIETIIKPVLPADWFAHCRSENIHVNPTGNFIIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNLVAAGLAERCEVQISYAIGVAEPTSVSVNTFGTGRIAESRLVELIQAHFDLRPVGLLQMLDLIRPIYRKTAAYGHFGREEPEFTWEQTDKAEALRDAAGLGPATAEIINVRSERH
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.