PharMolix/UniProtQA huggingface dataset:
Protein: SERC_YERPG
Sequence: MTQVYNFSAGPAMLPVEVLRRAEQELRNWHGLGTSVMEISHRSKEFMQVAEESEKDLRDLLQIPANYKVLFCHGGARAQFAAVPLNLLGDRNSADYIDGGYWAHSAIKEAQKYCTPNVIDVTTHDNGLTGIQPMKQWKLSDNAAYVHYCPNETIDGVAINEQPDFGNKVVVADYSSSILSRPIDISRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHTALPSILDYKVLADNDSMFNTPPTFAWYLSGLVFKWLKEQGGLGEMEKRNQAKAELLYGAIDRTGFYRNQVAITNRSWMNVPFQMADASLDKLFLSEAEAQGLQALKGHRVAGGMRASIYNAMPIEGVKALTDFMADFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_ARTS2
Sequence: MASPQEHSGPTTQPRGVPPVIAVVGPTGSGKSDLAVALALELDGEVINADAMQFYRGMDIGTAKITAEERRGVPHHLLDTLDVTEEASVSDFQWEARATIAEIHGRGKRAILAGGSGLYVRAALDVLEFPGTDPGIRRRLEEELDDAGLATLRRRLEAVDPVSAARLGDARRVVRALEVFELTGRAFSSFMPVREYYQPAVQIGLEVDRELLKDRLAQRVHGMVANGLQAEVQRLDAAGLRHGKTASRALGYSQFLKVLDGEWDTGQATEDTIVATRKFARRQLTWFRADPRIHWFDWQDPDLVAKALAVCR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: DNAK_MYCTO
Sequence: MARAVGIDLGTTNSVVSVLEGGDPVVVANSEGSRTTPSIVAFARNGEVLVGQPAKNQAVTNVDRTVRSVKRHMGSDWSIEIDGKKYTAPEISARILMKLKRDAEAYLGEDITDAVITTPAYFNDAQRQATKDAGQIAGLNVLRIVNEPTAAALAYGLDKGEKEQRILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDQRVVDWLVDKFKGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRAEFQRITQDLLDRTRKPFQSVIADTGISVSEIDHVVLVGGSTRMPAVTDLVKELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTRLIERNTTIPTKRSETFTTADDNQPSVQIQVYQGEREIAAHNKLLGSFELTGIPPAPRGIPQIEVTFDIDANGIVHVTAKDKGTGKENTIRIQEGSGLSKEDIDRMIKDAEAHAEEDRKRREEADVRNQAETLVYQTEKFVKEQREAEGGSKVPEDTLNKVDAAVAEAKAALGGSDISAIKSAMEKLGQESQALGQAIYEAAQAASQATGAAHPGGEPGGAHPGSADDVVDAEVVDDGREAK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: UBTD1_XENLA
Sequence: MGGCVGTHHDSSGSLNENSDGTGVALGRNQPLKKDKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGASITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDSETLDIPEPPPNSGHECQLRLRLSTGKDLRLMVRSADTVYHMKRRLHAAEGVEPASQRWFFSGRPLTDKMRLEELKIPKDFVVQVIVSQPIPNPTPVEN
What is the function of this protein?
May be involved in the regulation of cellular senescence through a positive feedback loop with TP53.
What are the official names of this protein?
Ubiquitin domain-containing protein 1.
Protein: PDXH_BURO0
Sequence: MTTLADLRINYSRASLDEADAAPDPFAQFDRWFKEALAAKLPEPNTMTLATVGADGRPSARIVLIKGVDERGFVFFTNYESRKGHDLAVHPQAALLFYWIELERQVRIEGRIEKTSAEESDRYFASRPLGSRIGAWASEQSAVIDSRATLEAREKAVSERYGDNPPRPPHWGGYRLVPDSIEFWQGRPSRLHDRLLYTRDATAAPGWTISRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: G6PI_SHIDS
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_SALG2
Sequence: MNLGTLVSETRNPQTMDLDALPTPELVKRFNEQDTRVAEAVKATLPDVARAVDAAVAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: Y1910_MANSM
Sequence: MAINSKYQDKQVDEILKDIIEVLEKHKAPVDLSLVVLGNMVTNLLTSSVGANQRTVLAQAFSDALLNSVKTKHH
What are the official names of this protein?
UPF0352 protein MS1910.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: SST_XYLFT
Sequence: MTEFIPPGSLFHALSSPFAMKRGGQLHHARIAYETWGRLNAGATNAILIMPGLSPNAHAAHHDSNAEPGWWESMLGPGKPIDTDRWFVICVNSLGSCKGSTGPASYNPITQAMYRLDFPALSIEDGANAAIEVVHALGIKQLASLIGNSMGGMTALAILLLHPDIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWKQGHYDDTHYPESGLRIARKLGVITYRSALEWDGRFGRVRLDSDQTNDTPFGLEFQIENYLESHAHRFVHTFDPNCYLYLSRSMDWFDVAEYANGDIIAGLARIRIQRALAIGSHTDILFPIQQQQQIAEGLRRGGTHATFLGLDSPQGHDAFLVDIAGFGPPVKEFLDEL
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.
What are the official names of this protein?
Serine O-succinyltransferase, SST.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOPJ_BACSU
Sequence: MKNTFLYFRWEDLHGEIGVDSFNLLRASYSNLSEQQLVELIKELISIEREDIAAKFDIHLSENAPVFDERQHVVYKGVAGDMNYKDMLLSLVTALDLTNTLDHVQNILSLAKCLRSFDREIFARFAKDIAEEVYYSLK
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YopJ.
Protein: ASSY_THEAC
Sequence: MDKALLLYSGGLDTSVMIKWIQENLSMDVATLTLNVGNSDLVAIEEKARMLGADPVFVHDAKDEFAEKFIAKSIMANGSYEGYPLSTALARPLMAEKAVKYAQKIGAKYIVHGSTGRGNDQVRFEVSIRALDPSMQVLVPVREWNMMRKDEVEYAKTHGIPVKLDGKYSIDENIWGRSVEGPDLEDIGKGVPEDVYEWVVPPWKANAEHTLKIAFDGGIPSEIDGEKMKLADLIVFLNTLAGSSGIGLIDHMENRVVGLKSHEVYECPAATVITHAHRYLESLILNRNEAEVKMNMDWQFAKFVYGGLWHDPVMNAVNAAEAEFNRDISGEIKIRMSHGIMYIEGAWGNSFLYSKDLINYSSMAFDQRASKGFIDIYGNATVHSHNRNPKMVKEVQGSSVEF
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_CAUVC
Sequence: MLGFAKKLFGSSNERKVKTLATRVAKINAYEAEYAALSDEALKGKTAEFKARLEKGETLDDILNEAFAVVREASKRVLGMRHFDVQMVGGMVLHFSGISEMRTGEGKTLVATLPTYLNALEGKGVHVITVNDYLARRDADWMGQVYNFLGLSYGVIVNGLSQGERQRAYRSDITYGTNNEFGFDYLRDNLVYSVDEMVQRGHNFAIVDEVDSILIDEARTPLIISGPTEDRSSFYKTIDVLVKELILDKSMFDHDEKQKQVILTEDGQEKIEEILMSGGHLAEDSAGLYDAANVSVVHHVNQALRANILYTRDKDYIVKGGEVVLIDEFTGRMMTGRRLSEGLHQAIEAKEGADIQPENQTLASVTIQNYFRLYKKLSGMTGTASTEAQEFDDIYKMSVSEIPTNRTIQRIDDDDEVYRTEREKNEAILKQIADCHVRGQPILVGTVSIEKSEELSKLLSTFSFEKDGKKVKGIPHQVLNARFHEQEAVIVADAGVPGAVTIATNMAGRGTDIQLGGSIDMRLFNWRQQQRGMGLEITVEDEAEERARLETEIADKKAQALAAGGLFVLGTERHESRRIDNQLRGRTGRQGDPGRSKFFLSCEDDLLRIFAGERLDAIMRTFGVQEGEAITHKWLNNAIATAQKRVEQRNYEIRKNLLKYDDVVNDQRKAVFEQRQEFMESSDLSDIIHEMRRDVIDDLVLRHLPPKAYAEQWDVEGLTERVKSILGLDLPIAEWAAEEGIADEEMKERITKAADEYAAQREVIITPEQMRSVEKSFLLQMIDLQWREHLMHLDHLRNVIGLRGYGQRDPLNEYKTEAFSLFEKLLGDLRTNTTRWLMTVEIAYAEPEVPHTPLDNLVEVHLDPLTGENAAFAGGIPEGLSTAQREALPVSALPEGWDRTNRNAPCPCGSGKKFKQCHGSLVR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: Y1677_STAS1
Sequence: MEKNQKINNAAYDQLNKDADRILQLIKVQMDNLTLPQCPLYEEVLDTQMFGLQKEVDFAVQLGLVDREVGKDLMLRLEKELSKLHDAFTNV
What are the official names of this protein?
UPF0358 protein SSP1677.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: MCES_DEBHA
Sequence: MSDKEAGVASSLGSNSPINKDEVDVKNTEEHSKQESKSDINKPPLKKIKADDGIDISDSFSRRENKGNNKVISSVYNDENKKTPAWMKSKTTDKYDKYGSRSTPIATPTAPVNNPDERYSKYMTNSVNSNDRVRRPPTETTSSQYDKKRAHDEAEDDVVAPYSNLAVANPSSNLYQTFQSHINNREGKDINSIVRSHYNQRTQQSKFQGSRTKSPIYKLRNFNNAIKYILLGNWVKPNPDSNRPTVILDLCCGKGGDLNKCEFVSVDQYIGIDISDASIKEAFSRYSRNKARFIPQTAESKKERDTRRYNFEACFATGDCFSSSIPEILEPNFPGIIDGLFPVDCVSLQFAMHYAFETEEKVHQLLTNVTKSLRAGGTLIGTIPSSDFIRDKIVNRAFIDQENRKFGNDLYSVTFHKDPPDEGVFRPPFGNGYNYSLKDAIDDVPEYVVPFEVFRGLCEEYGLVLKYKKNFIDIFNQEIPKYFSKLNKNLIEGMKRSDGKYGAEGLEKEAVGFYIGFVFEKLGN
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNLJ_CERSK
Sequence: MQDERPVDQLTEAEAAAELARLAEAIEAANTAYHTHDAPQISDADYDALRLRNRAIEEQFPELRRSDSPSDRVGGALAEGFAKVRHEVRMLSLENAFDLAEVEDWIERIRRYLGHVGDLLFTAEPKIDGLSLSLRYEKGRLVQAATRGDGETGENVTENARTIADLPTELDGAPDLLEVRGEVYMSHEDFAALNGRQEAAGQRLFANPRNAAAGSLRQLDPAVTASRPLRFFAYAWGAHSEPLAATQHEAIARLAALGFTTNPLTRLCTGPEELLAQHAEIERQRAALGYDIDGVVYKVDDLALQRRLGFRASTPRWAIAHKFAAQLAWTQLEGIDVQVGRTGALSPVARLKPVTVGGVVVANATLHNEDYIAGRDSKGQEIRGGKDIRVGDWVQVYRAGDVIPKVADVDLDRRPEGAAPYRFPETCPECGSEAIREPGDSVRRCTGGLICPAQQVERLKHFVSRAAFDIEGLGAKQVEALWRDGWIRQPADIFELPNRYREGIQRLENREGWGRKSAENLFAAIEARRRIALHRLIFALGIRHVGETTATLLATHYGSWAAFEAAMTRAEVGAGPEWQDLLSIDGVGAVLATSLVTAFHQEAERAAVEALAAHLTVEDAEVRAPVASPVAGRIVVFTGTLEKMSRAEAKARAEALGAKVSGSVSARTDLVVAGPGAGSKAKQAAALGIETIDEDGWLRLIGDA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MINC_SHEB8
Sequence: MSKPSLELKGASFTLSVLHINSSDLQAVMTELDSKLAQAPQFFLGAPLVVNLSAIQHDSLNLSALKDLLISRQLVIVGITGATTVLSKQAKDLGLAIVKAGKQSSTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGAAGDTSAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLDGESLMVESLPL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: RFT1_KLULA
Sequence: MNVKNEHMNKFANGVLFLMLGQTLSKGVNFLLNTLLVRYLSPRIFGITSFLEFLLSTVLFFSRESIRISTLRIKSTTDSGKLEKVEDGEDTRTLQSLINFGYIPFVIGLPLSIILISWQYSNLNSYFIDLPYFKASIFLIWLSILIELVSEPFYLVHQYLLNHFIRSKYESLGVTFACVANFIIVVWFEKMVNGVGLELHDDYKQEGIAIFAFAVGKLVHAMTLLACYSYNYYSEVYTTGERYSYKLTKIRPETRQESYYFQNDTVQHFKKVYFQLCFKHLLTEGDKLIINSLCTVEEQGIYSLLSNYGSLITRLLFAPIEEALRLFLARLLSVSSKKNLWLSMKVLIDLTKFYLYLSLFIIIFGPINSSYLLKFVIGSKWSSTSFLETIRTYCFYIPFLSLNGIFEAFFQSVASGDQIFKHSYVMMLFSGIFLFNCWLFIEYFDLSLEGLIVSNILNMALRIAYCGNFIHKFYHYLLKESSTETTQSILPNISTFKNVALIAAIIGALDWYFIGYVENMRELLINVILALLLLILVIYKEKSLISELLAAKTYAA
What is the function of this protein?
May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
What are the official names of this protein?
Oligosaccharide translocation protein RFT1.
What is the protein family that this protein belongs to?
Belongs to the RFT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ENO_ACIB5
Sequence: MSQIVDIRAREILDSRGNPTIEADVILESGVVGRACAPSGASTGSREALELRDGDKSRYLGKGVRTAVQNVNSSIHELLVGQSVFEQKALDEKMIAFDGTENKSKLGANATLAVSLAAAHAAAAEQKLPLFQYIANLRGQTTLTMPVPMMNILNGGAHADNTVDIQEFMIEPVGFTSFAEALRAGAEVFHSLKSVLKKQGLNTAVGDEGGFAPNLRSNEEAITVILQAIEQTGYKAGSDIMLALDCASSEFYKNGQYILEGEGNKSFTSNQFADYLAGLVKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFVTNPKILQRGIDEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVSKYNQLLRIEELTKAVYRGKAEFKGLN
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: UVRD_RICTY
Sequence: MKDKMQNQNFMHTLNSEQKKAALHTEGPLLLLAGAGTGKTKVLTSRIANIIQQNLALPHNILAVTFTNKAAKEMSERVHNLINCYGVNIGTFHSMAAKILRDQIENLNLGLNNKFTIISHDDQLTLVKDIVKLKKDIDTKKYTPKLIHIIISRWKDQGLLPSKLSASDTNLPLQRVAKLIYEEYQKNLLISNVLDFGDLLLYNNELFIKNPEILKYYQEKYRYILIDEYQDTNIAQYLWARMLASLYRNICCVGDDDQSIYGWRGAEVGNILRFEKDFAGATIIKLEQNYRSTLPILAAASNVINNNKNRHSKTLWTDSASGEKIKIISCLSDKEEARYIACEIDKLVREERYHAGNIAILVRAGFQTRSFEEAFINSAMPYKIIGGLRFYERMEIRDVLAYIRISLNQNDNLALERIINVPKRAIGAASLNKIRSYALERNISNFVAIKEILETGIFKAKSYESLKDLLTKIDNWYEKFITDTPINVVKTILDDSGYLSMLQEEKTEEAFGRIENINEMLRAIAEFNDIHDFIEHSSLVMENEVLETNYGGSVTIMTLHAAKGLEFDVVFLPGWEEGVFPSQRSLDEDGEKGLEEERRIAYVGITRAKKDLYITHAESRKIFYEIVHSCPSRFINEIPDEITIRTSSMKKYNSFYKF
What is the function of this protein?
Has both ATPase and helicase activities.  Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present.  Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity).
What are the official names of this protein?
DNA helicase II, DNA 3'-5' helicase II.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: HS3S5_MOUSE
Sequence: MLFKQQVWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPVESRFGGAHNQAELPLRALQFKRGLLHEFRKGNSSKEQVHLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan.  Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact).  This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.  Also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2 (By similarity).
What are the official names of this protein?
Heparan sulfate glucosamine 3-O-sulfotransferase 5, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5, Heparan sulfate 3-O-sulfotransferase 5.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: ARLY_LEPBL
Sequence: MTGKEKKLWGGRFQEKPSSILERIGESVSFDHKLYKEDIQGSIAHARMLKQIGILSGDELSKIETSLLQIKTELEEGKLEFKSELEDIHMHIESRLTELIGETGKKLHTARSRNDQVTQDVRLYILGRGKEILKSIVSLRFSLYEKAKRSVDVIIPGYTHLQVAQPIRASQYLLSWFWALERDQEFFRFALKASDELALGGGAMAGVNYATDREFLKKELGLSKVSPNSMDGVSSRDHILEFLFACTQLMIHASRICEDIILYSSQEFGILKLSDSLTTGSSIMPQKKNPDIAELIRGKAGRVIGNLNHLLVMLKGLPSTYNRDLQEDKLALFDSVETVEISLEGIREMIEDWVWVPERAESSLKNGFATATDLADFLVYEKKVPFRTAHELVGTLVRVCVEQKRTLFDLPEPDRIAVSEHFVGKEYENAVSLSLSADKKISYGGTSKKRQEEQLKIALESLKQTETLFL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOX1_HUMAN
Sequence: MVDAGGVENITQLPQELPQMMAAAADGLGSIAIDTTQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPSLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDSNEINVLTVALVNQDRENNIEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT
What is the function of this protein?
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface.  Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement.  The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock.
What are the official names of this protein?
Ecto-NOX disulfide-thiol exchanger 1, Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase, cCNOX, Cell proliferation-inducing gene 38 protein, Constitutive Ecto-NOX, cNOX.
What is the protein family that this protein belongs to?
Belongs to the ENOX family.
What are the subcellular locations of this protein?
Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
Protein: PO2F3_RAT
Sequence: MVNLEPMHTEIKMSGDVADSTDARSTFGQVESGNDRNGLDFNRQIKTEDLGDTLQQSLSHRPCHLSQGPTMMPGNQMSGDMASLHPLQQLVLVPGHLQSVSQFLLSQTPPGQQGLQPNLLSFPQQQSTLLLPQTGPGLTSQAVGRPGLSGSSLEPHLEASQHLPGPKHLPGPGGNDEPTDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSASTPSSYPTLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPVKPPIYNSRLVSPSGSLGSLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAMNPSSAAFNSSGSWYRWNHPAYLH
What is the function of this protein?
Inhibits transactivation by POU2F1.
What are the official names of this protein?
POU domain, class 2, transcription factor 3, Octamer-binding protein 11, Oct-11, Octamer-binding transcription factor 11, OTF-11, Transcription factor Skn-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RISB_THENN
Sequence: MKVVQGDYRGEGLKIAVVVPRFNDLVTSKLLEGALDGLKRHGVSDENITVVRIPGSMEAIYTLKRLLDLGVHDAIIVLGAVIRGETYHFNVVANEIGKAVAQFNMNSDVPIVFGVLTTDTLEQALNRAGAKSGNKGFEAAMVAIEMANLRKKLRRDFLEPHSNSRQ
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RL3_STRZT
Sequence: MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETDGYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAGRMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SECB_PASMU
Sequence: MSEENQVNAADTQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQVGDDLYEVCLNISVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYARELVSSLVNRGTFPALNLSPVNFDALFMDYLQRQEQAEQTTEEENKDVH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTPQ_BACSU
Sequence: MKMTSRKLSDILKQRLQHENRSFLFDREKDTLRVEDQTTKKGITLDLPPIIAKWELKKDEAIDEIVYYVSEAMTAMEGKAQEMTGKETRIYPVIRSTSFPDKSSEDIPLIYDDHTAETRIYYALDLGKTYRLIDQRMLEKENWTKERIRETAAFNLRSLPTVVKEDTVAGNYFYFFRANDGYDASRILNEAILNEYKQHAEGELAISVPHQDVLILADIRNESGYDILGQMSMSFFAGGTVPITALSFLYNEGKLEPVFILAKSRPKKD
What are the official names of this protein?
UPF0354 protein YtpQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: RS9_PROM5
Sequence: MNSQIKNKAVYWGTGRRKTSVARVRLIPGNGQIKINGRSGDDYLNFNPSHLNSVKAPLQTLGLENSYDIFVNVFGGGLTGQADAIKQGAARALCDLSPDNRKPLKTEGHLSRDPRAKERRKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS6_LACGA
Sequence: MAKTKYEVTYIIKPDIDEDSKKALIDRFDKVVTDNGAEELESKDWGKRRFAYEIEKYREGTYHIMTFVAENSEPVDEFGRLSRIDNQVLRSMTVKLDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.