PharMolix/UniProtQA huggingface dataset:
Protein: METXS_PSESM
Sequence: MPTVFPHDSVGLVTPQTAHFSEPLALACGRSLPAYDLIYETYGQLNAARSNAVLICHALSGHHHAAGFHSADDRKPGWWDSCIGPGKPIDTDKFFVVSLNNLGGCNGSTGPSSIDPDTGKPFGANFPVVTVEDWVNSQARLADVLNIDTWAAVIGGSLGGMQALQWTISYPDRVRHCLAIASAPKLSAQNIAFNEVARQAILTDPEFHGGSFQERGVIPKRGLMLARMVGHITYLSDDSMGEKFGRGLKSEKLNYDFHSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAANFNDDLAKTFANATARFCVMSFTTDWRFSPARSRELVDALMAARKDVCYLEIDAPQGHDAFLIPIPRYLQAFGNYMNRISL
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O16A_CONAI
Sequence: MKLTCVMTVAVLFLTAWTFVTADDSRNGLKNLFPKARHEMKNPEASKLNKRDGCSNAGAFCGIHPGLCCSEICIVWCT
What is the function of this protein?
Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.
What are the official names of this protein?
Delta-conotoxin-like AVIA, Delta-AVIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AROK_YERPS
Sequence: MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFFDSDQEIERRTGADVGWVFDVEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQVDEPPREVLEALAKERNPLYEEIADVTIRTDDQSAKVVANQIINMLESN
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 1, SK 1.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFDA_BURSR
Sequence: MSINSEYLHPLFVGQVDNLALQGALSPAEVRDVENEMDQKAVLVFRGQPLDQDQQIAFARNFGQLEGGFIKVNQRPSRFKYAELADISNVSVDGKVAEADAREVVGNFANQLWHSDSSFQQPAARYSMLSAIVLPPSGGDTEFCDMRAAYDDLPEDFKKELQGLRAEHYALHSRFILGDTEYSESQRNAMPPVSWPLIRTHAGSGRKFLFIGAHASHIEGRPVAEGRMLLAELLEHATQPKFVYRHSWKVGDLVMWDNRCVLHRGRRYDVTARRELRRATTLGRRCRLSPRGQSWVQ
What is the function of this protein?
Involved in degradation of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D).  Is also able to degrade 2-methyl-4-chlorophenoxyacetic acid and 3-chlorobenzoic acid.
What are the official names of this protein?
Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase, 2,4-D dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the TfdA dioxygenase family.
Protein: PMP10_CHLPN
Sequence: MKSQFSWLVLSSTLACFTSCSTVFAATAENIGPSDSFDGSTNTGTYTPKNTTTGIDYTLTGDITLQNLGDSAALTKGCFSDTTESLSFAGKGYSLSFLNIKSSAEGAALSVTTDKNLSLTGFSSLTFLAAPSSVITTPSGKGAVKCGGDLTFDNNGTILFKQDYCEENGGAISTKNLSLKNSTGSISFEGNKSSATGKKGGAICATGTVDITNNTAPTLFSNNIAEAAGGAINSTGNCTITGNTSLVFSENSVTATAGNGGALSGDADVTISGNQSVTFSGNQAVANGGAIYAKKLTLASGGGGGISFSNNIVQGTTAGNGGAISILAAGECSLSAEAGDITFNGNAIVATTPQTTKRNSIDIGSTAKITNLRAISGHSIFFYDPITANTAADSTDTLNLNKADAGNSTDYSGSIVFSGEKLSEDEAKVADNLTSTLKQPVTLTAGNLVLKRGVTLDTKGFTQTAGSSVIMDAGTTLKASTEEVTLTGLSIPVDSLGEGKKVVIAASAASKNVALSGPILLLDNQGNAYENHDLGKTQDFSFVQLSALGTATTTDVPAVPTVATPTHYGYQGTWGMTWVDDTASTPKTKTATLAWTNTGYLPNPERQGPLVPNSLWGSFSDIQAIQGVIERSALTLCSDRGFWAAGVANFLDKDKKGEKRKYRHKSGGYAIGGAAQTCSENLISFAFCQLFGSDKDFLVAKNHTDTYAGAFYIQHITECSGFIGCLLDKLPGSWSHKPLVLEGQLAYSHVSNDLKTKYTAYPEVKGSWGNNAFNMMLGASSHSYPEYLHCFDTYAPYIKLNLTYIRQDSFSEKGTEGRSFDDSNLFNLSLPIGVKFEKFSDCNDFSYDLTLSYVPDLIRNDPKCTTALVISGASWETYANNLARQALQVRAGSHYAFSPMFEVLGQFVFEVRGSSRIYNVDLGGKFQF
What are the official names of this protein?
Probable outer membrane protein pmp10, Outer membrane protein 5, Polymorphic membrane protein 10.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: END3_MYCTU
Sequence: MPGRWSAETRLALVRRARRMNRALAQAFPHVYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADRTELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGRKTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIERKEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPLVQGPETDHLLALAGL
What is the function of this protein?
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity.  The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site.  The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.  Has a preference for oxidized pyrimidines, such as thymine glycol (prefers 5S isomers) 5,6-dihydrouracil:G, 5-hydroxyuracil:G, 5-hydroxycytosine:G and urea:A.  Cleaves ssDNA containing an AP site.
What are the official names of this protein?
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: CIAO1_CANAL
Sequence: MVQLLHSIKAHNDKVWSVSVHPTLPIIATASTDKSTKLYKLSARQKFPLVAKLEDTHKRSIRSVAFKPPLGGADTPKSDFLDLPALAAGSFDSTISVWGIDEPDVEYDIEEVIANQKEILTSPNNEWNLMAIIEGHENEVKAVDWNFQGQYLASCSRDKTVWIWETDPETLEEFECVAVLNDHSQDVKNVSWHPSMNILASSSYDDTIRIYQQDIAGDEWSCVGILNGHEGTVWCSKFESLKSPIADSSVLRLVSASDDLSVRIWVAKREQEDDEQAKLELPSSIRHTNEMVWEVESVLPSVHKYPVYSVAWSALTGKIASAGSDGKIVVYSETEKGKWVIDSIHEGAHGVHEINCVIWAQLDDENEILVSAGDDGYVNLWKI
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Preferentially localized to the nucleus.
Protein: SGT1_YEAST
Sequence: MPVEKDLKTAYKALYDEKEPLKALHLYDEILKGSPTNLTALIFKAACLEKLYFGFSDWHSDATMENAKELLDKALMTAEGRGDRSKIGLVNFRYFVHFFNIKDYELAQSYFKKAKNLGYVDDTLPLWEDRLETKLNKKNKKQKDSTNKHTIKPVESIENRGDNNSSHSPISPLKIETAPQESPKFKIDWYQSSTSVTISLFTVNLPESKEQVNIYISPNDRRTLSISYQVPKSGSEFQYNAKLSHEVDPKAVSLKIFPKKLEITLSKIDSTQWKKLEEDILTESSRLSDEGKNSDSATRLLSAETASKERLSYPSSSKKKIDWSKLDIDEEADEEAGSADSFFQKLYAGADPDTKRAMMKSFIESNGTALSTDWEDVSKGTVKTSPPEGMEPKHW
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Required for both entry into S phase and kinetochore function.  Also involved in cyclic AMP (cAMP) pathway, possibly by participating in the assembly or the conformational activation of specific multiprotein complexes.
What are the official names of this protein?
Protein SGT1, Suppressor of G2 allele of SKP1.
What is the protein family that this protein belongs to?
Belongs to the SGT1 family.
Protein: VDCA_VIBCH
Sequence: MMTTEDFKKSTANLKKVVPLMMKHHVAATPVNYALWYTYVDQAIPQLNAEMDSVLKNFGLCPPASGEHLYQQYIATKAETNINQLRANVEVLLGEISSSMSDTLSDTSSFANVIDKSFKDLERVEQDNLSIEEVMTVIRRLVSDSKDIRHSTNFLNNQLNAATLEISRLKEQLAKVQKDALFDSLSGLYNRRAFDGDMFTLIHAGQQVSLIMLDIDHFKALNDNYGHLFGDQIIRAIAKRLQSLCRDGVTAYRYGGEEFALIAPHKSLRIARQFAESVRRSIEKLTVKDRRSGQSVGSITASFGVVEKIEGDSLESLIGRADGLLYEAKNLGRNRVMPL
What is the function of this protein?
Diguanylate cyclase (DGC) that catalyzes the synthesis of cyclic diguanylate (c-di-GMP) via the condensation of 2 GTP molecules.  Is involved in the modulation of intracellular c-di-GMP levels.  Cyclic-di-GMP is a second messenger which positively regulates biofilm formation and negatively regulates virulence in V. cholerae, and is proposed to play an important role in the transition from persistence in the environment to survival in the host.  Overexpression of vdcA results in increased biofilm formation, and reduced motility and virulence.
What are the official names of this protein?
Diguanylate cyclase VdcA, DGC.
Protein: UPPS_ALIF1
Sequence: MTSQINNEFLSLDVLPKHIAVIMDGNGRWAKAQGKPRVFGHKAGVDAVRKTISAASKLGINAITLFAFSSENWRRPEEEVSVLMELFITVLSREVKRLHKNNIQLRIIGETSQFSSRLQKKIVEAETLTSENTGLVLNVAANYGGKWDITQAVRRLAYQVERGNLQADDIDEDLIASKLTMSDLPEVDLMIRTSGECRISNFMLWQMAYAEFYFTDQYWPDFNEQSLADAVAWFVSRERRFGCTGEQIQALMNEKDQ
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: GLB7X_CHITH
Sequence: MKFFAVLALCIVGAIASPLTADEASLVQSSWKAVSHNEVEILAAVFAAYPDIQNKFSQFAGKDLASIKDTGAFATHATRIVSFLSEVIALSGNESNASAVNSLVSKLGDDHKARGVSAAQFGEFRTALVAYLQANVSWGDNVAAAWNKALDNTFAIVVPRL
What are the official names of this protein?
Globin CTT-VIIB-10.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PTH_SALHS
Sequence: MAIKLIVGLANPGAEYAATRHNAGAWYVDLLAERLRAPLREEPKFFGYTSRITLEGEDVRLLVPTTFMNLSGKAVGAMASFYRIQPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKSKVVGFVLGKPPVSEQKLIDEAIYEAARCTELWFKEGLAKATSRLHTFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDEC_ECOLI
Sequence: MSHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVYDTVTKTFFSLSKEASAATFSPLIHLKDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQIMNPAEFIPLAEKEGMIEQITDYVIDNVFRDLGDYLATHADRYVSINLSASDFHTSRLIARINQKTEQYAVRPQQIKFEVTEHAFLDVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
What is the function of this protein?
Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG (By similarity).  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria.  Overexpression reduces biofilm formation (PubMed:19460094).
What are the official names of this protein?
Probable cyclic di-GMP phosphodiesterase PdeC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RK22_POPAL
Sequence: MIKKRKKNPYEASASGFYISMSAHKARRIIDQIRGRSYEETLMILELMPYRACYPIFKLVYSAAANASHNMGLNEASLVISKAEVNEGATMKKFKPRARGRSYLIKRPTCHISIVLEDISYEEYEEDFLRRI
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SEM3C_MOUSE
Sequence: MAFRAICVLVGVFICSICVRGSSQPQARVYLTFDELRETKTSEYFSLSHQQLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEPLSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKERLTDNNRSTKQIHSMIARICPNDTGGQRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSASGELILEELEVFKNHVPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVRNNSTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQDSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWAGSVRALPFHPKDILGAFSHSEMQLINQYCKDTRQQQQLGEEPQKMRGDYGKLKALINSRKSRNRRNQLPES
What is the function of this protein?
Binds to plexin family members and plays an important role in the regulation of developmental processes.  Required for normal cardiovascular development during embryogenesis.  Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance.
What are the official names of this protein?
Semaphorin-3C, Semaphorin-E, Sema E.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU1B_SOLPN
Sequence: MASITANHPISGKPLISFRPKNPLLQTQTLFNFKPSISKHSNSSFSIPVVRCSIRRIPEYTPSHIPDPNYVRIFDTTLRDGEQSPGATMTTKEKLDVARQSAKLGVDIIEAGFPASSEADLEAVKLIAKEVGNGVYEEEYVPVICGLARCNKKDIDKAWEAVKYAKKPRIHTFIATSEVHMNYKLKMSRDQVVEKARSMVAYARSIGCEDVEFSPEDAGRSDPEFLYHILGEVIKAGATTLNIPDTVGYTVPEEFGQLIAKIKANTPGVEDVIISTHCQNDLGLSTANTLAGACAGARQLEVTINGIGERAGNASLEEVVMALKCRGEQVLGGLYTGINTQHILMSSKMVEGISGLHVQPHKAIVGANAFVHESGIHQDGMLKHKDTYEIISPEDIGLNRANESGIVFGKLSGVMLCKPKMLELGYEIEGKELDDLFWRFKSVAEKKKKITDDDLVALMSDEVFQPQFVWQLQNVQVTCGSLGLSTATVKLIDADGREHISCSVGTGPVDAAYKAVDLIVKVPVTLLEYSMNAVTQGIDAIASTRVLIRGENGHTSTHALTGETVHRTFSGTGADMDIVISSVRAYVGALNKMMSFRKLMAKNNKPESSAVI
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase B, Alpha-IPM synthase B, Alpha-isopropylmalate synthase B.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: TYPH_SHEB9
Sequence: MFLAQEIIRKKRNGLALSSEEIQFFVQGITTNSVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLGLNGPVIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIQGYQTEPSSELFRKVVKEVGVAIIGQTGDLVPADKRFYSIRDNTATVESISLITASILSKKLACNLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLTDMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYEVTMGLCAEMLLLGGLASNEADARAKLNRVLDNGRAAELFGKMVSGLGGPVDFVENYSKYLPQSQIIRPVFADMQGYAYSMDTRELGLAVVTLGGGRRKPGDTLDYSVGLTQVCALGDKVDSSTPIAVIHAQSEAAFAEAELAVKKAIHIGETAPEKTPEIYAYIRASDL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: YKL2_CAEEL
Sequence: MNKSKEAETDITQIFPNLDILPKKFSAKELAERRIKKLHVAPGSIFMNRWSIEGVIGNGGYGQIFMVMDVKKNDERAMKIEPKLRAEVITKRMIMEQQVLMKMQGKTHIPTMYASGFNDQFNFIIMQLLSMNVGDFRKRSPLGRLSKETVGRIAYQTLNALKDIHDMGYVHRDVKPANICFGVHAQNRHILYLLDFGLVRRFKTESGVCIPWRINAGFKGTERYVSVRVHEKLEQTPWDDAFSVLYTAYELVVGELPWRYLEDIHEIHGVKKLMNEVTKNGEMFKDIASILVDFHKMILECDPVVELPYEKLLECLKCLYSPKSLLEPYDWEDGYKTTLNI
What are the official names of this protein?
Putative casein kinase I C03C10.2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Protein: Y3194_SOLUE
Sequence: MPDNSFDIVSKIEMPEVHNAVQQAMKEVQQRFDLKDSHSNIELKEKDNKILLQSSDEYKLKNVIDILQSKLVKRNVPLKGLAYGEIIPSAGSTVKQEITLQQGIAIEKARDIVKKLKDSKLKVQASIQGDFVRVAGKDRDTLQSAIALLRGSDFGIDMQFTNYRTN
What are the official names of this protein?
UPF0234 protein Acid_3194.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: LUXI_ALIFS
Sequence: MTIMIKKSDFLAIPSEEYKGILSLRYQVFKQRLEWDLVVENNLESDEYDNSNAEYIYACDDTENVSGCWRLLPTTGDYMLKSVFPELLGQQSAPKDPNIVELSRFAVGKNSSKINNSASEITMKLFEAIYKHAVSQGITEYVTVTSTAIERFLKRIKVPCHRIGDKEIHVLGDTKSVVLSMPINEQFKKAVLN
What is the function of this protein?
Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation.
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein LuxI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: HIS2_BURA4
Sequence: MTQSTEDTLLRLAAVIDSRKGGDPDQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPTALVGEVADLWFHCLVMLSHFDLSPADVIGELERREGLSGIEEKALRKRREREENGG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_ECOLU
Sequence: MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG72_BPML5
Sequence: MVPVTLYVDIDLEEYIKSYGFVGPLSAKSDLKETARQVVEFELARAGFKAKVHLRKPV
What are the official names of this protein?
Gene 72 protein, Gp72.
Protein: VMH3_VIPAA
Sequence: MIQVLLVIICLAVFPYQGSSIILESGNVNDYEVVYLQKVTAMNKGAVKQPEQKYEDTMQYEFKVNGEPVILHLEKNKDLFSEDYSETHYSPDGREITTNPPVEDHCYYHGRIQNDADSTASISACNGLKGHFQLRGETYFIEPLKIPDSEAHAVYKYENVEKEDEAPKTCGVTQTNWESDELIKKASQLNLTPEQQRYLNSPKYIKLVIVADYIMFLKYGRSLITIRTRIYEIVNLLNVIYRVLNIYIALVGLEIWNNGDKINVLPEAKVTLDLFGKWRETDLLNRRKHDNAQLLTGINFNGPTAGLGYLGSMCNPQYSAGIVQDHNKVNFLVALAMAHEMGHNLGMDHDGIQCTCGAKSCIMSGTLSCEASIRFSNCSQEEHRKYLINKMPQCILNKPLKTDIVSPAVCGNYLVELGEDCDCGSPRDCQNPCCNAATCKLTPGSQCADGECCDQCKFGRAGTVCRPANGECDVSDVCTGQSAECPTDQFQRNGHPCQNNNGYCYNGTCPILGKQCISLFGASATVAQDACFQFNRLGNEYGYCRKENGRKIPCAPQDVKCGRLYCFDNLPEHKNPCQIYYTPRDENKGMVDPGTKCGDGMACSSNGQCVDVNTAY
What is the function of this protein?
Zinc metalloprotease that has fibrinogenolytic and hemorrhagic activities.  Cleaves insulin B chain readily at '38-Ala-|-Leu-39' bond, and at a significantly slower rate, at '40-Tyr-|-Leu-41' bond.  Hydrolyzes isolated extracellular matrix (ECM) bovine fibronectin, and basal membrane (BM) proteins human collagen IV and, to a lesser extent, murine laminin, in vitro.  Cleaves murine nidogen (at '350-Ser-|-Phe-351' and '380-Tyr-|-Asn-381' bonds), but not laminin, in a solubilized BM preparation.  Hydrolyzes plasma proteins involved in blood coagulation in vitro.  It significantly prolongs thrombin time.  Has potent alpha-fibrinogenase activity cleaving human fibrinogen alpha chain at '432-Lys-|-Leu-433' bond, but does not cleave beta or gamma chains.  Hydrolyzes bovine prothrombin, but does not cleave it at '366-Arg-|-Ile-367' bond, which is necessary for the formation of active alpha-thrombin, however, the cleavage of fragment 1 from it leads to reduced alpha-thrombin formation.  Hydrolyzes bovine factor X heavy chain at '211-Ser-|-Leu-212', '213-Asp-|-Leu-214' and '216-Gly-|-Leu-217' bonds activating it only marginally as does not cleave at the physiological activation site.  Does not cleave factor X light chain.  No hydrolysis or activation of plasminogen.  The alpha-fibrinogenase activity likely contributes to its hemorrhagic activity, which in rat can be completely neutralized in vivo by anti-ammodytagin antibodies, which strongly cross-react with this protein.  Has very weak collagen-, ADP- and ristocetin-induced platelet aggregation inhibition activity in vitro.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like protein H3, H3 metalloproteinase 1, Hemorrhagin 3, P-IIIc metalloproteinase H3, Snake venom metalloproteinase, SVMP, VaH3.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIc sub-subfamily.
Protein: VP8_MYRV9
Sequence: MADLTSTSVNQTVLATQPLTTRELQQIRSMVQTSSNLMQFGNHTALPDSYLETFLFNNGVVYEDGDVFYAWSETVHHPTFLDAQDQRYSLELHPIEHDQTVSPNVSHSVWWQCADFNKFRTLSVFGRRVVPRVRYHVDEFTITFSVSVPLRCRSFQDYYDIHVQMKMRTPSPSVHDPTHISLASEIESISNDNDVSVPAVVSQPNEITINVGALTPYVGHSSKLAGAALSMIMNIPRKPVPASPAPRVHPAVLLTHSFFDFVREQISRMDATIMPIHLVEQTFPEAFLAIPVPRDIETGLVTALRSVAMVPTSQYNLHVMAERVQSQSMDWTGGNFSRIPMHDDDIIMTHDTITALSTGVSTYHHHLAITEDDMAVIKSRVPGVIKYRGSIDDLKALSNLLESPRTHQVLLHSIATIHIYDIGDESEIDDQEMYSKKISFLFLLAYLMECVTLPTTLSQGFEPRLPLLPSSRVPFYLAFGV
What are the official names of this protein?
Uncharacterized protein VP8.
Protein: RPOC_STUS1
Sequence: MKDLLNLLKNQGQIEEFDAIKIALASPEMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVALAKVRRERMAHIELASPVAHIWFLKSLPSRIGLLLDMTLRDIERVLYFESYVVIDPGMTTLEKGQLLNDEQYFEALEEFGDDFDARMGAEAVRELLIQIDLEHEIGRLREEIPQTNSETKIKKLSKRLKLMEAFHGSGNLPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLSAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFGKLEMRGMATTIKAAKKMVERELPEVWDVLAEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTREAINAKGEGRVFADLQEVDRVFRAGEASLHARVKVRINETIKDRDGSITKNTRIVDTTVGRALLFQIVPEGMSFDVVNQPMKKKAISKLINLCYRTVGLKDTVIFADQLMYTGFAYSTISGVSIGVNDFVIPDEKARIIDAATEEVKEIESQYASGLVTQGEKYNKVIDLWSKANDEVSKAMMANLSKEKVIDREGNEAEQDSFNSMYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEIDCGTEQGLHMTPHIEGGDVVEPLGERVLGRVIARDVLKPGTDDVLVPAGTLIDEQWVDFIELNSIDEVIVRSPISCETRYGICAKCYGRDLARGHQVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRTSAVDNVLVKNGGTIRLHNLKHVERADGALVAVSRSGELAVADDFGRERERYKLPYGAVISVKEGDKVDAGAVVAKWDPHTHPIVTEMKGVVTFVGMEENITIKRQTDELTGLTNIEVMDPKDRPAAGKDIRPAIKMVDANGKELLLPGTDVPAQYFLPANALVGVADGAEINVGDVIARIPQETSKTRDITGGLPRVADLFEARRPKEPSILAEISGTISFGKETKGKRRLVITPTDGSDPYEELIPKWRHLNVFEGEQVNKGEVISDGPSNPHDILRLLGVSALARYIVNEIQDVYRLQGVKINDKHIETILRQMLRKVEITESGDSSFIKGDQMELTQVLEENERLSAEDKFVAKYVRVLLGITKASLSTESFISAASFQETTRVLTEAAVTGKRDYLRGLKENVVVGRLIPAGTGLAYHSERKRKRDAEKPVRVSADEVEAALTEALNSSGN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.