PharMolix/UniProtQA huggingface dataset:
Protein: DXS_GEOKA
Sequence: MTKIDHPRVVKNMSIPELKRLSAEIRRFLIEKLSKTGGHIGPNLGVVELTIALHREFDSPKDKLIWDVGHQSYVHKILTGRAAAFDTLRQYKGLSGFPKRSESEHDVWETGHSSTSLSAAMGMAIARDLKGTDEYIVPIIGDGALTGGMALEALNHIGHEKTDMIVILNDNEMSIAPNVGALHNILGRLRTAGKYQWVKDELELLLKRIPAVGGKLAATAERLKDSLKYLLVSGVFFEELGFTYLGPVDGHDFEDLFENLRYAKKMKGPVLVHVITKKGKGYSPAENDKVGTWHGTGPYKIETGAFVKTKEAGPSWSALVSETVRRLARTDPRIVAITPAMPVGSKLEGFASEFPDRMFDVGIAEQHATTLAAGLATQGMKPFLAIYSTFLQRAYDQVVHDVCRQNLNVFFAIDRAGLVGADGETHQGVFDIAFLRHVPNLVLMMPKDENEGQHMVYTAIRYDDGPIAMRFPRGNGLGVPLDEELKEIPIGTWEVLRDGCDAAILTFGTTISMALKAADELAKDGISVKVVNARFLKPMDVAMLHELLESRLPILTVEEAVLQGGFGSAVLEFAHDHGYHGAVIERMGIPDRFIEHGSVSELLNEIGLTSTHIIDRIKTMVPRKQKRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: NUOC_POLSJ
Sequence: MLSSFPVSATQLGDTIAAVLGDKVKSLKIALGEVTVTVGAADYLASAVLLRDAAGCRFEQLIDLCGLDYSEYKDGQYDGLRYCVASHLLSVSLNQRVRLKVFCPDDDFPVVDSVNGVWNSANWFEREAFDLYGIIFEGHNDLRRILTDYGFIGHPFRKDFPTTGYVEMRYDAEQKRVIYQPVTIEPREITPRVIREDNYGGLQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL11_GLOC7
Sequence: MAKKIVAIIKLALPAGKANPAPPVGPALGQHGVNIMAFCKEYNGKTSDQVGMVIPVEISVFEDRSFTFVLKTPPASVLIRKAAGVERGSNEPNKKNVGSITQDQLREIAQTKMPDLNANDIEAAMKIVAGTARNMGISVKD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: VATE_BORGP
Sequence: MQFEVKDLINKIKKDGLEEAERISNDIIFKAKKEAEEIVARAEEAVGALKAKSEKEINDYKRHALEASRQAIRDLIIGVEKNLKSLFENTLKDNVAEVFSDNDFLSELIIKITDSWIKEEKLVIQLNESDFSGLEQILRLKLGNKLKEGIEIKPFKGISKGFKIQKKNTGLQYDFSVETIADILFDYLNPRFKEVIKVV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: CEAB_ECOLX
Sequence: MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSMPPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAARTVLENGLRGGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPASQLPAAGNNVPVKYRLTDLMQNGTQYMAIIGGIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNLPDLVLSVGQMNTPVRSNPEIQEDGVISETGNYVEAGYTMSSNNHDVIVRFPEGSGVSPLYISAVEILDSNSLSQRQEAENNAKDDFRVKKEQENDEKTVLTKTSEVIISVGDKVGEYLGDKYKALSREIAENINNFQGKTIRSYDDAMSSINKLMANPSLKINATDKEAIVNAWKAFNAEDMGNKFAALGKTFKAADYAIKANNIREKSIEGYQTGNWGPLMLEVESWVISGMASAVALSLFSLTLGSALIAFGLSATVVGFVGVVIAGAIGAFIDDKFVDELNHKIIK
What is the function of this protein?
Colicins are polypeptide toxins produced by and active against E. coli and closely related bacteria.
What are the official names of this protein?
Colicin-B.
What is the protein family that this protein belongs to?
Belongs to the channel forming colicin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMD_VIBA3
Sequence: MARFFQPKKKTQLETKHQSVLVERMDHNGAGIAYQKNKPVFIDGALPGEKVVIQLTESKSKFSRAKLIKLLQPSELRLKPFCKHFNQCGGCHLQHLGYSSQVEHKSQSLTHLMSKYQTANTEVALPIVGDESGYRRRARISLFVDKKTQLLQFGFRKKQSKQIENITDCAVLDPRLNVLLPKLKSLLNTFSSLTSLGHVELVLGDTGPVMVLRHLKPLVEKDEQALMTLMTLAKEEGATLYSMPETDKLVRLVGDAPSYSETGVTLPFEPNHFIQVNQKVNQQMVAQAIEWLEPQADERVLDLFCGLGNFSLPIAQQSAFVVGVEGVDEMVQQATANAALNQLSNTEFYQANLEEDLSSQLWAKEKFDKVLLDPARAGASGIVDQISALGAKRVVYVSCNPATLARDSESLEKQGYQLAKLGMLDMFPHTSHLESMALFIKA
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: Y2164_YERPB
Sequence: MSELCPCGSILNYHECCGPYILGTQVAAKPAILMRSRYCAYVEKNVDYLIATWHPDCHAQEWRESIIQGFTKTVWHGLTVIAETPGRHPDEAFVEFIARFTDADNAQITAMHERSRFLRIKEHWYYIDGIRPSLGRNDTCLCGSGKKHKKCCGR
What are the official names of this protein?
UPF0225 protein YPTS_2164.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: PAND_SALPC
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWRPKVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_ALKEH
Sequence: MGPDQEGLTYKAAGVDIDAGNELVDRIRDDVKRTMRPGVLGGLGGFGGLFEVPVDRYRRPVLVSGTDGVGTKLKLAIETGRHDGIGIDLVAMCANDVLVTGAEPLYFLDYYATGRLDVEVAAAVIRGIAEGCHQAGAALIGGETAEMPGMYAEGHYDLAGFCVGVVEKDEIIDGSRVGAGDALIALAASGPHSNGYSLIRKVLERAPEGAATEVDGQPVADLLMAPTRIYAKPVLDLIRNLPVHAMAHITGGGLPENLPRVLPEGLGAKLQPWSWPPVFRWLQQTGQIAEAEMLRTFNCGVGMVLVVPAEQADAALQRLRQTGETAWRLGEIGTHEAGAPRVQVVAA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XDH_CALVI
Sequence: MTQEHNAAVLDLNPTFSTLIFFVNGKKVIDTNPDPECTLLTYLREKLRLCGTKLGCGEGGCGACTVMISRIDTLTNRIKHIAVNACLTPVCAMHGSAVTTVEGIGSTRTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRNLSQPSMKDLEIAFQGNLCRCTGYRPILEGYKTFTKEFGCAMGDKCCKVNGNKCGEGMENGGDMVDDKLFEKSEFVPFDPSQEPIFPPELQLNKDWDSQTLVYKGERATWYRPGNLEDLLKIKAQFPEAKLVVGNTEIGVEVKFKHFLYPVLVNPTKVKEMIDVQELEDSIYFGASVSLMDIDRILRSSIEKLPEHQTRFFQCAVNMLHYFAGKQIRNVASLGGNIMTGSPISDMNPVLMAGAVKFKVAKYVEGQIKYREVCMASGFFTGYRKNVIEPTEILVGLYFPKTLEHQYVVAFKQAKRRDDDIAIVNAAINVFIDPRSITVDKVYMAFGGMAPTTVLATRTADIMVKQQWNKVLMERVVENLCAELPLAPSAPGGMIAYRRSLVVSLFFKAYLTITQQLIKSGILPQDSLPQEELSGSDVFHTPALKSAQLFEKVSNKQSECDPIGRPKIHASALKQATGEAIYCDDMPRMENELYLALVLSTKAHAKILSIDASEALAMPGVHAFFSSKDITQHENEVGPVFHDEEVFASDMVYCQGQVIGAIAADNPNFSSKTARKVTIEYEDIKPVIITIEQAIEHKSYFPDYPRFTEIGDVEKAFSEADHVYEGSCRMGGQEHFYLETHASLAVPRDSDEIEIFCSTQHPSEVQKLVAHVLSTSAHRVVCRAKRLGGGFGGKESRAIAVALPVALACHRLRRPIRCMLDRDEDMMITGTRHPFLFKYKIAFTSEGRLTGCYIECYNNAGWSMDLSFSVLERAMFHFENCYKIPNIKVGGWVCKTNLPSNTAFRGFGGPQGMFAGEHIIRDVARILGKDYLEIMKQNFYKEGDITHYQQKLDNFPIEKCFYDCLQQSNYYQKRKEIEEFNRNHRWRKRGISLVPTKYGIAFGVSHLNQAGALINIYADGSVLLSHGGVEIGQGLHTKMIQCCARALQIPIEFIHISETATDKVPNTSPTAASSGSDLNGMAVLDACEKLNKRLAPIKEANPNGSWTEWINKAYFERVSLSATGFYRMPDIGYDPVQNPNALMYNYFTNGVGSSIVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEEMIYSPQGVLYSRGPGMYKLPGFADIPGEFNVTILTGAANPRAVYSSKAVGEPPLFIGCSVFFAIKEAITSARLMNGLSEDFKLESPATSARIRMACQDEFTNLIEQPPAGSYVPWNIVP
What is the function of this protein?
Key enzyme in purine degradation.  Catalyzes the oxidation of hypoxanthine to xanthine.  Catalyzes the oxidation of xanthine to uric acid (By similarity).
What are the official names of this protein?
Xanthine dehydrogenase, XD.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: NUOK_FRATO
Sequence: MRALKMNSISVSVTHGLIFSILLFVISVAGIIINRRNILILLMSIELMLLAVNTNFLIFANMHQQAMGGVFVFFIMAVAAAETAIGLAIVVAIFRKRKTIDLSKLNTLRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HBD_LEONI
Sequence: VHLTGEEKSAVAALWSKVNVDEVGGEALGRLLVVYPWTQRFFESFGALSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFAQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGKEFTPRVQAAFQKVVAGVATALAHKYH
What are the official names of this protein?
Hemoglobin subunit delta, Delta-globin, Hemoglobin delta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: HEMH_CITBB
Sequence: MSSKTALLLLQMGGPDSLDAVHPFLMNLFTDRDIIKIGPAFLQPFIARRIVNKRAPKVEEYYRQIGGKSPIRELTEAQGEGLQQLLGEDFRSFVAMRYSRPSTIDALAAIKRAGIERVIALSLYPHYSKATTGSSLNELKRVLKESGAKFEISYIDRFYNHPLYIKALSEKVVQGLASFPDRKDVEIVFSAHSLPQSFIEEGDPYLDHIQETVRLVMEQVGEGSHTLCFQSKASRVKWLEPSTEATIEQMAKAGKKNLLMVPLSFVSDHIETLYEIDIQYGEEAKALGIERFVRSESLNSSPLFLECLADLVKTAAK
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIPC1_RAT
Sequence: MPLGLGRRKKAPPLVENEEAEPSRSGLGVGEPGPLGGSGAGESQMGLPPPPASLRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPAAEVMFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSSGGHPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
What is the function of this protein?
May be involved in G protein-linked signaling.
What are the official names of this protein?
PDZ domain-containing protein GIPC1, GAIP C-terminus-interacting protein, GLUT1 C-terminal-binding protein, GLUT1CBP, RGS-GAIP-interacting protein, RGS19-interacting protein 1, Synectin.
What is the protein family that this protein belongs to?
Belongs to the GIPC family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: PSAJ_SOLTU
Sequence: MRDLKTYLSVAPVLSTLWFGALAGLLIEINRFFPDALTFPFF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: IOD3_HUMAN
Sequence: MPRQATSRLVVGEGEGSQGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLGRRRRGQPEPEVELNSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVLPDGFQSQHILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGARPRRV
What is the function of this protein?
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine).  RT3 and T2 are inactive metabolites.  May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones.  Can regulate circulating fetal thyroid hormone concentrations throughout gestation.  Essential role for regulation of thyroid hormone inactivation during embryological development.
What are the official names of this protein?
Thyroxine 5-deiodinase, 5DIII, DIOIII, Type 3 DI, Type III iodothyronine deiodinase.
What is the protein family that this protein belongs to?
Belongs to the iodothyronine deiodinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: CCMB_ARATH
Sequence: MRRLFFELYYKLIFSSTPITSFSLFLLYIVVTPLMLGFEKDFLCHFHLGLIWISLLFSFLSALFFRNEKEDGTLELYYLSTYCLPKILLLQLVGHWVIQISCVFCGFPMLQLLYQFGRSGMDWLNILLGSLVLTLLCGIHSCLALGITSSSGWNSSQNLTTLPTLLPLTVFCTSIETEWFHVLLLIGYFFLFVSLFPISVSISLQD
What is the function of this protein?
May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Putative cytochrome c biogenesis ccmB-like mitochondrial protein, ABC transporter I family member 2, ABC transporter ABCI.2, AtABCI2.
What is the protein family that this protein belongs to?
Belongs to the CcmB/CycW/HelB family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RNB_ECO57
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVRKDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3L21_NOTSC
Sequence: MKTLLLTLVVVTIVCLDLGDSLICYMGPKTPRTCPRGQNLCYTKTWCDAFCSSRGKVVELGCAATCPIAKSYEDVTCCSTDNCNPFPVRPRPHP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Alpha-elapitoxin-Nss2a, Alpha-EPTX-Nss2a, Long neurotoxin 1, LNTX-1, Notechis III-4.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_PSYA2
Sequence: MSNKPSLSYKDAGVDIDAGDALVQRIKSVAKATSRPEVVGGLGGFGALCRIPTGYTSPLLVSGTDGVGTKLKLALQLNRHDTIGIDLVAMCVNDLLVCGAEPLFFLDYYATGKLDVDVAATVVTGIGEGCKLSNCALIGGETAEMPGMYQDDDYDLAGFCVGVVEEAEVITGENVTEGDVLIALASSGAHSNGYSLVRKVIEVSGVDVTSSNEQLDGQSIQDALMAPTRIYVKAIKALQDTLGSSALHAMSHITGGGLTDNLPRVLPDHLAASIDTSSWQFSELFTWLQTQGNIEQSEMYRTFNCGVGFVIVVPKDKADAAIKTLTDAGEKAWKLGEMVSREADAVVYR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_PASMU
Sequence: MSLTNEQIIEAIASKSVTEIVELIAAMEEKFGVSAAAAAVAVAAGPAEAAEEKTEFDVVLAGAGANKVAVIKAVRGATGLGLKEAKDLVESAPAVLKEGISKAEAEALKKELEEAGAQVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CC74A_HUMAN
Sequence: MSGAGVAAGTRPPSSPTPGSRRRRQRPSVGVQSLRPQSPQLRQSDPQKRNLDLEKSLQFLQQQHSEMLAKLHEEIEHLKRENKDLHYKLIMNQTSQKKDGPSGNHLSRASAPLGARWVCINGVWVEPGGPSPARLKEGSSRTHRPGGKRGRLAGGSADTVRSPADSLSMSSFQSVKSISNSGKARPQPGSFNKQDSKADVSQKADLEEEPLLHNSKLDKVPGVQGQARKEKAEASNAGAACMGNSQHQGRQMGAGAHPPMILPLPLRKPTTLRQCEVLIRELWNTNLLQTQELRHLKSLLEGSQRPQAAPEEASFPRDQEATHFPKVSTKSLSKKCLSPPVAERAILPALKQTPKNNFAERQKRLQAMQKRRLHRSVL
What are the official names of this protein?
Coiled-coil domain-containing protein 74A.
Protein: MTNA_PYRAB
Sequence: MEVRYKPEELTKLPRSVEYKERTVYMINQRLLPREFKVEAFRTVESVAEAIKNMTVRGAPAIGAAAAFGLALYAETSKAKSKDEFMDGFYKAYETLKNTRPTAVNLFWALNRIKKLVEEHLEDPLDEIKSLIVNEAQKIADEDVEANLRMGHYGAEVLPEGNLLTHCNAGSLATVHLGTVGAVVRVMHKDGSLKLLWLDETRPVLQGARLSAWEYSYDGLNVKLIADNAAAFVMQQGLVDAIIVGADRIVANGDFANKIGTYMLAVLAREHGIPFFAVAPLSSIDMSLKSGKEIPIEERSPEEVLTCGGCRIAPDVPVYNPAFDVTPHKYVTGIITDKRVVWPPFKRNLKKLFGEQ
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Putative methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, MTNA-like protein, aMTNA, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: END4_BACFR
Sequence: MKYIGAHVSASGGVEFAPVNAHEIGANAFALFTKNQRQWVSKPLTEDSIRLFKENCEKFGFAPEYILPHDSYLINLGHPEEEGLTKSRAAFLDEMQRCEQLGLKLLNFHPGSHLNKISVEECLDRIAESINLALEKTKGVTAVIENTAGQGSNLGNEFWQLKYIIDRVEDKSRVGVCLDTCHTFTAGYDFLNDYDDVFGEFGEVVGFEYLRGMHLNDSKKELGSRVDRHDSIGKGLIGFAFFEKLMKDPRFDNMPLILETIDETLWPEEIAWLREQTQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: SECA_NOVAD
Sequence: MFGSIAKALFGSSNDRYVKSLDKIVRQIAAFEPHVQALSDEELAAQTPKFRQMLAEGKTLDDILPEAFATVREASVRALGMRHFDVQMIGGIVLHRGEIAEMRTGEGKTLVATLAVYLNALEGKGVHVVTVNDYLARRDAETMGVLYNFLGLTVGVIVPNLNEEQRREAYNADITYATNNELGFDYLRDNMKHERGQMVHRPFNFAIVDEVDSILIDEARTPLIISGPTDDKSDLYISVDAVVKQIAPDLYEADEKTKNITLTEDGVEWVERAFEDAGLLVGSNLYDVENTMVVHHLDQALKANVMFKRDIDYIVKDGKIVIIDEFTGRMMDGRRWSNGLHQAVEAKEGVKIEPENQTMASITFQNYFRMYPKIAGMTGTAATEAPEFFDIYKMNVVSIPTNVPVQRIDEEDEFYKNTMDKFGAIAKLIRERYENGQPVLVGTVSIEKSELLSEFLQKEGVKHNVLNARFHEMEAHIVAQAGRLGAVTIATNMAGRGTDIQLGGNVEFRIEDELRDVPEGPEREAGIARIRAEVAEEKQKVLAAGGLCVIGTERHESRRIDNQLRGRSGRQGDPGMSKFYLCLEDDLLRIFGPDTLFARMMNSNLADGEAIGSKWLSKAIETAQKKVEARNYDIRKQVVEYDDVMNDQRKVIYEQRADIMDAEAVGDVVTDMRHDTVNAIVGDACPPGSYPEQWDVESLKARVRDVLGIEIPLDDWFQEEAIEPDTIEERIQQLADAHMDTKITEVDASAWRSLEKSILLERLDHHWKEHLATLDALRQVVFLRAYAQKTPINEYKQEAFGLFEKMLDAIREDVTRILMTSEIRLRPVEEFQLPELPDFLTSHIDPFTGENDAAPLAPAPSMFGALPPQAGGALSGGFPDGDPFAGQGISRNAPCPCGSGQKYKHCHGVAA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CYC_PANTR
Sequence: MGDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE
What is the function of this protein?
Plays a role in apoptosis.  Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.  Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: TYRO_STRGB
Sequence: MTVRKNQAALTADEKRRFVAAVLELKRNGRYDEFVRTHNEFIMSDTRTGRRGGPGHRLPLPFLPWHRRFLLDFEQALQSVDSSVALPYWDWSTDRTVRASLWAPDFLGGTGRSSDGRVMDGPFAASTGNWPVNVRVDGRTFLRRSLGTGVRELPTRAEVDSVLSMATYDMAPYNSASDGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYNRQLWAEWQRRHPGAGYVPTGGTPDVVDLNDTMKPWNDVRPADLLTHTAHYTFDV
What is the function of this protein?
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.
What are the official names of this protein?
Tyrosinase, Monophenol monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
Protein: YCF3_NUPAD
Sequence: MPRSRINGNFIDKTSSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEAMRPEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQASNNMAVICHYRGEEAIRQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITGRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SEC62_HUMAN
Sequence: MAERRRHKKRIQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSKWAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNEVYVWIYDPVHFKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILLLAVARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS
What is the function of this protein?
Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER).  Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides.  Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen.
What are the official names of this protein?
Translocation protein SEC62, Translocation protein 1, TP-1, hTP-1.
What is the protein family that this protein belongs to?
Belongs to the SEC62 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.