PharMolix/UniProtQA huggingface dataset:
Protein: RL5_STRPN
Sequence: MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEAVSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTTANTDEESRALLTGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GPDA_LACJO
Sequence: MAKIAVLGNGSWGSVLGSMLADNGNDVVLYGNIDSVNQEINEHHTNTHYMKNWKLNPNVPATGDLEKALDGAEIILFVLPTKAVRIVAKNARKILDKTGATPLLVTATKGIEPGSKKLISDILTEEVYPNDSEKIVAISGPSHAENVAQKDLTAIACASTSEENAKRVQKIFSNNYVRFYTNDDLVGVEVGGAVKNVIAIAAGILVGKGYGDDAKAALMTRGLAEITRLGVKYFGAKPMTFSGLSGIGDLIVTATSQNSRNWRAGKQIGEGKSLDYVLDHMGQVVEGATTVKAVHELAEEKNIDMPISEAIYRVLYENADVDQEIKTMMGRNPKPEIQL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_RICRO
Sequence: MRNIIYFILSLLFSVTSYALETINIEHGRADPTPIAVNKFYADNSAADVLGHDMVKVISNDLKLSGLFRPISAASFIEEKTGIEYKPLFAAWRQINASLLVNGEVKKLESGKFQISFILWDTLLEKQLVGEILEVPKNLWRRAAHKIADKIYEKITGDAGYFDTKIVYVSESSSLPKIKRIALMDYDGANNKYLTNGKSLVLTPRFARSADKIFYVSYATKRRVLVYEKDLKTGKESVVGDFPGISFAPRFSPDGRKAVMSIAKNGSTHIYEIDLATKRLHKLTDGFGINTSPSYSPDGTKIVYNSDRNGVPQLYIMNSDGSDVQRISFGGGSYAAPSWSPRGDYIAFTKITKGDGGKTFNIGIMKACPQDNKNSERIITSGYLVESPCWSPNGRVIMFAKGWPSSAKAPGKNKIFAIDLTGHNEREIMTPADASDPEWSGVLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HUGA_VESMG
Sequence: MLLVTLFLFFLQALVNGDSCGSNCEKSERPKRVFNIYWNVPTFMCHQYGLYFDEVTNFNIKHNSKDNFQGDKIAIFYDPGEFPALLPLNYGKYKIRNGGVPQEGNITIHLQRFIEYLDKTYPNRNFSGIGVIDFERWRPIFRQNWGNMKIYKNFSIDLVRKEHPFWNKKMIELEASKRFEKYARLFMEETLKLAKKTRKQADWGYYGYPYCFNMSPTNFVPDCDVTARDENNEMSWLFNNQNVLLPSVYIRRELTPDQRIGLVQGRVKEAVRISNKLKHSPKVFSYWWYVYQDETNTFLTETDVKKTFQEIVINGGDGIIIWGSSSDVNSLSKCTRLREYLLTVLGPIAVNVTEAVN
What is the function of this protein?
Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides.
What are the official names of this protein?
Hyaluronidase, Hya, Hyaluronoglucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYV_RICTY
Sequence: MKEFPKHYNFIENEKKWQHIWQELQIYAYNPNMSKEGIYIVDTPPPTVSGQLHIGHIYSYTQTDFIVRFQRMIGKNIFYPIGFDDNGLPTERLVEKQKQIKAYNMERDEFIKICQEVVQNEEAKFRNLFKQIALSVDWSLEYQTISPLSRKISQMSFLDLLHKGEVYRANQPILWDTVDGTALAQADIEDKQKISSMNYIMFKTEQGDKLTIATTRPELLPACVAVFYHPDDGRYKHLADKSAITPLFNEKVPILADPLVQQDKGTGLVMCCTFGDQTDITWWKSHNLPLKTIITKKGTINFPHKIDLDGLTIKEARTKIIDILKEQNLLTKQEEITQTVKCAERSGAPLEILTVTQWFIKTITHKEALLKRTNELNWYPKNMQMRLENWINSLSWDWCISRQRYFGVPFPIWYSKRIGEEGKILYADISQLPVDPLKDLPIGYSKEEVDPDLDVMDTWATSSVSPQLSTYGISEDFAINKVRHDKLFPMDLRPQAHEIIRTWAFYTILKSHLHQNILPWKNIMVSGWCLAEDRSKMSKSKGNVLVPEKLLERYGADVIRYWSANSKLGADTAYSEDIMKNGKRLVNKLWNAAKFVSIHFDKLTSEDKKVSLCAIKEKITHEFDQWIINKLVALVKLATNALQNYEYANAIYLTEKFFWSIFCDNYLEISKTRSYDEGNKNPQGQYSSILTSYHVMQTLLKLFAPFMPHITEELYQILYSKNSIHIQGNWVNYGDLNYDIDVQGPEGLLTILDIVRKFKAEYNLSIKAPIKLLEVSGIILSTELVEDLKNVTSAEAIQFEMKDDKIKVNIKLFV
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR3_HUMAN
Sequence: MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMEMNSIEPAKETTTNV
What is the function of this protein?
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane (PubMed:9477959, PubMed:26176916).  Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate (PubMed:9477959, PubMed:26176916).  Does not mediate fructose transport (PubMed:9477959, PubMed:26176916).
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 3, Glucose transporter type 3, brain, GLUT-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Localized to densely spaced patches along neuronal processes.
Protein: RBFA_SHESM
Sequence: MAKEFSRTRRIGQQLQQELAVVLQRDMKDPRIGFVTVNDVDVSRDLSYAKVFVTFFEEDKEVVQEKLNALIAAAPYIRTLVAGRMKLRVMPEIRFVYDSSLVEGMRMSNLVSQVINSDKAKQQQFGSADDVTENDIDEADDTEGKA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_ALIFM
Sequence: MDDNKKKALAAALGQIEKQFGKGSIMKLGDNRTMDVETVSTGSLSLDIALGAGGLPMGRIVEIFGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVYAKKLGVNIDELLVSQPDTGEQALEICDALARSGAVDVMVIDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGNLKQSNCMAIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAVKDGDEVVGNETRIKVVKNKIAAPFKQAETQIMYGQGFNREGELIDLGVKHKLVDKAGAWYSYNGDKIGQGKANASKFMRENTEVAAELDKKLREMLLTPAEEKPETDAAPEIEENEEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y055_SYNJB
Sequence: MDTRLINIGFGNIVAAGRVVAIVSPESAPIKRIISDARERGQLIDATYGRRTRAVIITDSGHVILSAIQPETVANRFLTAKPGLSEETE
What are the official names of this protein?
Putative regulatory protein CYB_0055.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: RL25_SYNWW
Sequence: MLGQKLNARKREIKNRGYLNQLKRSEQVPAVIYGKGEEAVPIILEKRELNRIFNVHGSRGLFSLEIEGESKPMMTLIREIQRNPVSGQLIHLDFLSVNLNEKINSNVGVLLGGEEEVMKKGGILQAGLKEVEVLCFPQDLPEYLSADISSLEIGETLHVADLIVPAGVEILTEAESVIASILAPSKATTGEEEGAEAAGEGEEAEEKPE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RNH2_BURO1
Sequence: MTAIRAPRRRASSDVQGGFDFSRPDEIVCGVDEAGRGPLAGPVVAAAVILDPAQPIDGLDDSKVLSAKKRDALYDLIVTRSHAYCVASASVDEIDTLNILHATMLAMKRAVEGLSVLPTLAQIDGNRCPTLSVRAEAIVSGDALVPSISAASILAKVTRDRMLVDLHERFPVYGFNVHAGYGTAKHLAALREHGPCEAHRRSFAPVRAALDLIR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
Protein: GET1_AJECN
Sequence: MPSLLITVLFLNVIIYVINTVGAATVDGLLWLLYIKLPTGTSQIAREQRHMKREVVQLKHEMSSTSSQDEFAKWAKLRRRHDKAMEAYEAKNNELTQSKSTFDMTIKIARWAATSGLMLFLQFWYSKTPIFTLPPGWIPWQVQWVLSFPRAPMGTVSIQIWGGACATVVALVGDAMRASLAYVSKPKIDRIKLGATMEGKEGKKRQ
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein GET1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HPRK_STRP7
Sequence: MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: PLAP_ECOLI
Sequence: MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIVVLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYEDVA
What is the function of this protein?
Putrescine importer.  Required for induction of type 1 pili-driven surface motility.
What are the official names of this protein?
Low-affinity putrescine importer PlaP, Putrescine low affinity permease.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_ACIBY
Sequence: MNEKKQSRLRRAKSTRLHIRALGATRLCVNRTPRHIYAQVISADGGKVLAQASTLDASLRSGTTGNIEAATKVGALIAERAKAAGVTKVAFDRSGFKYHGRIKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TMP_BPSPP
Sequence: MEGARLQAVVTANIREFQRKMAAVNRIVRTTANRVTVTVDSRTEKFENAMNRLARITGSLSTVIGGALRGALMSAFPAAVPAAASLVGVVGSLGPMLGVAAGGAAGLGSAFATAGAGAVAYGALAATSIGGVIKASQDLDKLQAKLDDATDAKERAKIMEQIKNLQASLGKEERKALDTLEDFKSNWQDIAKSVQKPILRTFTTSLNTFKSVLNQLQPMFRGLARGGESLAKSMQNAFKAPDMKNFINYLNTEAPGAFVSFGKISGNIIRTVMNLMVAFGPLGKNMTKSIEGATAAWVKWSASLGSSVKFQKFIAYVQTNGPKLLKIIGNLSSGITSLFTGFAPLSADMMTSLVNLTARFKEWAASAKDSKEFKSFIDYIRTNGPIVWDSLGKIAKTLINLAVAMAPVGSEVLKMVNSFAQWTAATTKAHPEIGKFMAVAISLGGALRALTPVIISFQTLFGGFSSIGKAIDLIKKFKTSAAGIKLAAAIADMKLFTKTNALMAAQMAKTKFTNMITQLGLFGTKLRLQMSIMAAYLKQLVVAAAQQTAFAVKMAASYAQMKITSFITALKNGIIQMGLWIKNMAIMAAQSAANAVKMAAAWTAARISAFASMLAAGIKQMIAFGVRLAALAAAAAANAARMAASWVIAMGPIGWITAAVIALVALIIANWDKIKEYTVKIWGAVSKWLSDAWNKIKQAASVVWQALVTLIKKNFEMQKKIVTTVWNTIKSVSSKVWNGIKSFLSSVWNGIVNAGKTVWNGLKTFFTAWLNFQKKTWSTIWNAVKTAVTKVWKGIVSVGKTVWNGLKSFFTSWLNGQKKLFSTVWNAVKTAVTNVWNKLKSAASSTFNALKSSVTNIMNKVKDKIKSIWNSVMSFFKGINLGSIGRNIMQGLINGVTSMWGRVTSTFSRLTNAIPKTIKKILGIHSPSRLMRDEIGYHIGTGLVKGITGTEGMVTKAAASLAKSAVPEVPTVPELAVNSSYSGGMVEQSVNASLENFDLPEKNIIIQMDKREVGRAVEEPVREFTGRKRKRR
What is the function of this protein?
Serves as a base for tail tube protein polymerization and acts as a template for tail length determination.
What are the official names of this protein?
Tail tape measure protein gp18, Gene product 18, gp18.
What are the subcellular locations of this protein?
Virion. Note=Probably present inside the tail tube.
Protein: PHS_PSEF5
Sequence: MTALNQAHCEACRADAPQVSDEELPVLIKQIPDWNIEVRDGVMQLEKVFLFKNFKFALAFTNAMGEISEAEGHHPGLLTEWGKVTVTWWSHSIKGLHRNDFIMAARTDEVAKTAEGRK
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: NUOC_METPB
Sequence: MEAITTNGITLRRTVAAAQGDDALRAMGERITGALGPAVTDWSIAHGELTLIVQGSDIVYALTYLRDDPNCAFRCFIDICGVDYPQRARRFDVVYHLLSLRHNMRVRVKVQTDAATPVPSAIPVFPAANWFERETYDLYGILFSGHPDLRRLLTDYGFEGHPLRKDFPLTGFVEVRYDQDEARVVYEPVKLTQEFRNFDFLSPWEGTDYVLPGDEKKSS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL17_PSEU2
Sequence: MRHRKSGRHLSRTSSHRKAMFQNMAVSLFEHELIKTTLPKAKELRRVAEPLITLAKEDSVANRRLAFDRTRSKEIVGKLFNDLGKRYATRQGGYLRILKCGFRAGDNAPMAYVELVDRPIGGSVEAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: OPGB_ECO8A
Sequence: MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNITLFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRRHHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDPKLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVDTHHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIAAFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNYLGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELALSTDWCVSQGQLGGQQIVQHVDKTTWQGKTAFKDTVIDMARYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITAKAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGNILGHSPRKLGIGMVEIKVVEREG
What is the function of this protein?
Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones.
What are the official names of this protein?
Phosphoglycerol transferase I, Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the OpgB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PFDA_METMA
Sequence: MAEVSEEIRNLAARHQEFQRQAEALRQEMSMVQASIASCDQAIATINELKAASEAGRAAETMVPVGFGSYVYAEVKNPDKVVVNLGAGFSAEETAEAAVETLNRRKEQLTKILEQMNASLTKIAQGMQALETEAAKIQPGQA
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKSF_BACSU
Sequence: MTKCNLPEVVVTGVGVTASIGQGKEDFASSLLSGRHAFDVMKRSGRQKDSRFIGAEIASLSYPDRLSKKMLRKASFSSRAALVTLTEAWEEAELDDADSSRIGLVVGGSNFQQRENFEVYERYQDRSGFISPAYGLSFMDSDLCGICTDQFGITGLAYTVGGASASGQLAVIHAIQQVLSGEVDTCIALGALMDLSYMECEALRALGAMGTDKYADEPENACRPFDQNRDGFIYGESCGALVIERKETALRRGLKPYAALSGWSIKLDGNRNPDPSLEGEIHVIQKALERARLLPEDIDYINPHGTGSFIGDEIELKALRACRLSHAYINATKSITGHGLSAAGIVEIISVLLQMKKSALHPSRNLDHPIDDSFHWVNEKSISYRIKNALSLSMGFGGMNTAVCIQNIEKCGGES
What is the function of this protein?
Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.  It decarboxylates selectively the malonyl group attached on the acyl-carrier-protein AcpK (Mal-AcpK).
What are the official names of this protein?
Polyketide biosynthesis malonyl-ACP decarboxylase PksF, Malonyl acyl-carrier-protein decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_NITHX
Sequence: MTDVPRMVTPERRSDDVGDTVLRPQRLAEFVGQAQARANLQIFIDAARKRKEALDHVLFVGPPGLGKTTLAQIVARELGVGFRATSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEVLYPAMEDFQLDLIIGEGPAARSVKIELSKFTLVGATTRAGLLTNPLRDRFGIPVRLNFYTVDELEKIVSRGARVLDVGMTADGANEIARRARGTPRIAGRLLRRVRDFASAADAASINRKIADHALGALEVDAAGLDAMDRRYLTTIALNYGGGPVGVETMAAALSEPRDAIEDIIEPFLIQCGYLQRTPRGRLLTSHAFRHLGLTEPSRDPSQFGLFGGEDE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MSBA_METFK
Sequence: MSKTALGKANASVQSARALYLRLLKYAARYWVAFLISIIALVTFSATNTGFLATIKLVTDAGFVNQDSTKLHLLPFMLFGLLAIRALAGFISNFAMRWVARRVVENLRQDTFRRLMSLPVSFFDAVSAGVVTSKLTYDTEQMAGAATKVAMSAVRDTLTILGMVGYMLYLDWQLTLIFAVVAPAMAWYLKSMTPKLRSSGKAVQQTMGEMTKVIEEAVSGQRMVKIFGGGDYEYQRFTKVAGKNRHMQIRLARFSGLNSMVVELLAGVALALVVFYAVGKFSAGEFAAFIGALLMLIGPVKTLTSLNEELQVGLAAAHSVFELIDSIPEVDEGHEEIGRAEGSIVFENVTLQYPSAQRPALLDLNFTVKPGEKIALVGRSGGGKTTLVNLLPRFYEVQQGRVLIDGVDVRNMSLKSLRQQFSLVSQDVILFNDTVFNNIAYGVLRNASEEDVIAAAKAAHAWDFIQQLPNGLQSEIGDRGVRLSGGQRQRLAIARAILKNAPILLLDEATSALDTESERHVQAALDELMQNRTSIVIAHRLSTIENADRIMVMEQGRIIEGGSHEELLALDGHYAKLYRKQFH
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RDGC_SHEHH
Sequence: MWFKNLTVYRFNKPFSVDPDSLEKSLEDFTFSPCSSQDISKFGFSKAMGKHGETLIHTAGDRHLICATKEEKILPSQVIKEALEEKVGHLEAEENRKLTKKEKDALKDEITTTLLPRAFSRRSQIRALILPEIQMILVDSSSAAKSEELMALLRKAIGTLPIIPISFKTPIETQLTEWLKEGKTPPAFEMQDEAELKSDSDEGGIVRFKQQDLSENEVLAHIEVGKQVHKLALHFGQSIAFVLQSDAAIKRLKFSEEFRADNDDLGNDDPMARLDADFALMSSELIALINAVVDALGGLEDSI
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HEM6_PECAS
Sequence: MSDINAVKHFLLSLQKDICQQLAAIDGGADFAEDEWQRAEGGGGCSRVLSGGRIFERTGVNFSHVTGKSLPPSASTHRPDLAGRSFQAMGVSLVIHPLSPYIPTSHANVRLFVAEKPGEEPVWWFGGGFDLTPYYGFKEDAVHWHQTAHDLCQPFGDDVYPRYKKWCDDYFFLKHRNEARGIGGLFFDDLNEPDFATSFAFIRAVGNGFLDGYLPIVERRKDLAWGERERDFQLYRRGRYVEFNLIWDRGTLFGLQSGGRTESILMSMPPLARWEYQHQPEPDSPEAALYRDFLPARDWLAESNTHNKEA
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.