PharMolix/UniProtQA huggingface dataset:
Protein: GSM1_CANAL
Sequence: MTKKLTPQEKKNRKPAVRACVFCHQKHLQCSNERPCKNCVKRNIAHGCQDIVRKRVKYLTGESVPGAVSNKQSTPRKKLKTGPVSTSVSPMDSVKSELTTPVESSNHFPPPMSSSVDALPTTQHSAIEIPPNDQPISDILEVPPLFDSSHMISSEAPETNITLTTQNLITPDPLSFHTNTVSNTTTDVLNKLLNDNYETESMLSANNSNGDHLLGMAHTSSGHLSNGQQFQSNYLNEEYMMLGDIILQSKQASPSPSNTSTSENNTNTLSPSSFGYISNINFEDFNQPKRKVVQKLKDSRPFISLGFTADLAPHDNNNNTDYYDDKMTNNITGKTEEGPGNPIINYNTKFTTDYVPPSITNNLYKTASDLYSKELKNFYYPLSYHALTKLLKVIFGGNDLSPEEKQEKRSKLLIILKLIASYRPTFIAAHRDLIQEDLLMLEMTLQRSLLDYKKLAELNSSPTIMWRRTGEIISITEDMALLLEHSSFDLLKERRFIFELMDDNSIVDYFNLFANIAVGNLKSVIQTAIQMKTKSSNLIKFTCVFTIKRDIFDIPMIVIGQFLPIV
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.
What are the official names of this protein?
Glucose starvation modulator protein 1, Zinc finger domain-containing protein 23.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_BRUA1
Sequence: MPKRVLQGVVVSDKNDKTVVVKVERRYSHPLLQKTVRQSKKYKAHDENNQFKVGDFVSIQESAPISKDKRWVVLTSEAAG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y1065_LISMO
Sequence: MTFKGFSKKDFKTMQISGLEARMTGIQNDIQPKFRAVGEELTTYLSAKLGDEMFLHIARHQRRSVNPPDSTWLAICHDKRGYKKHPHFQVGLFDKYLFIWLAFIYENEESLKIANRFLKEKKLLADLPDNFAISPDHTEEKTYPVHDGQLEATLERFRDVKKGEFLVGKIYLPDDNHLSPAKDFIKEAEMVLDELIPLYKAALQ
What are the official names of this protein?
UPF0637 protein lmo1065.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: RL24_LACLM
Sequence: MFVKTGDTVKVIAGKDRGTTGKVIKALPKVNKVVVEGVAIMKKHQKPNSENPSGAILEIEAPIHVSNVQVLDKNGVAGRVGYKVVDDKKVRFNKKSGEILD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TMP2L_NEMVE
Sequence: MGKDSFTPLYDGGDSSHVHLNKFGSNQLSQSKKSWIARNFSRRECIRFVPKSHDVSRCKCGRPRERHSQQALESGQGSEEWNVASCTTKHPTNAYGEIDFEGYGGQKRAPYLRMSHDTDANLVITLMLKRWNLEIPNLVISVTGGAKSFVLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDTQVNVIGIATWGIVDKQSDLISEKNGKYPALYSMEPTPGHQGAMLDPNHSHFFLVDDGTEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAYNHTIKRNVDGQTINVIDPQYEDEVRAKVVEVFGAKGADKTYSMIKDVLEDEKMISVYSLDGEISQDIDLAILKALLKANRSSPVAQLNLALAWNRIDLAKSDIFTEEQQWTTETLSAAMLTALLDDKAEFAELFLQNGLSMREFLSLDILCKLYAEVPGNTTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYYRKDGHYFGELASYAEGLVLKNRKSSKDLLANINRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRAQEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCLYLPVLIFPIIYFVPDEQHERQAAEREHQKSLNQKSSKVKSHKEKNDAPVVPVYRSKEEKAVSNDEEARVGTENEEEDFQLEDYIPEIREDDSMEVIMRNKKLGFCDRIMHFYSAPFSKFVGNVVGYLAFIFLYAYVVLFNFPRFDPAKTLGGIHPTEIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTNSRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGELFLDEIQGEKPKEFGEVDPDGRWLSPLLLAIYMVFTNILLLNLLIAIFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIFIRWVWRMCRCGHPPRGSTMKIGLSPAEMEQMDNWEFQAAEMYIHQQQQKNSGTLEERVRALGDRVDCINSQLNRVLDSMSGTRAHALTDGNGLEGGHDSEGRLARMEVELSSNSESLQKILALLQQQPPVKGQAAVPIQLTLLHYKARSSPYPGSTAKRFAVQDNMVDWQVPFPDYKPVNYTAPVVLANPVWADKDLMAMSPRPELPYNQMDHTCNVNRVSYNGTYVVKDGLPLNPMGRTGMQGRGLLGRFGPNHAADPVVTRWKRTSAGVMLQGGKKVLEFVAIQRKDNNQWAIPGGMVEPGQLVTQALKAEFGEEAMAKLNVSQEEKERIAKQIERLFQQGQEIYKGYVDDPRNTDNAWMETVAVNFHDDKGDLFGDITLQAGDDAAAVRWQRVSGNIPLYASHVSILEKVAKMRDAAF
What is the function of this protein?
Nonselective, voltage-independent cation channel that mediates Ca(2+) and to a lesser extent Na(+) influx, leading to increased cytoplasmic Ca(2+) levels (PubMed:25620041, PubMed:27333281, PubMed:28775320, PubMed:29745897).  Functions as ligand-gated ion channel (PubMed:25620041, PubMed:27333281, PubMed:28775320, PubMed:29745897).  Binding of ADP-ribose causes a conformation change; the channel is primed but still requires Ca(2+) binding to trigger channel opening (PubMed:25620041, PubMed:27333281, PubMed:28775320, PubMed:29745897).  May have ADP-ribose pyrophosphatase activity which reduces ADP-ribose levels induced by oxidative stress, thus preventing the channel activation by reactive oxygen species (PubMed:25620041, PubMed:27333281).
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member-like 2, nvTRPM2.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PG187_VACCW
Sequence: MNFQGLVLTDNCKNQWVVGPLIGKGGFGSIYTTNDNNYVVKIEPKANGSLFTEQAFYTRVLKPSVIEEWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGADLDAVIRANNNRLPKRSVMLIGIEILNTIQFMHEQGYSHGDIKASNIVLDQIDKNKLYLVDYGLVSKFMSNGEHVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKNCALVSATKQKYVNNTATLLMTSLQYAPRELLQYITMVNSLTYFEEPNYDEFRHILMQGVYY
What is the function of this protein?
Essential serine/threonine-protein kinase that plays different role in the viral life cycle (PubMed:1560522, PubMed:1602551).  Phosphorylates the host small ribosomal protein RACK1 thereby customizing the ribosomes to a state optimal for viral mRNAs (which contain poly-A leaders) but not for host mRNAs (PubMed:28636603).  Facilitates viral DNA replication by inhibiting host BANF1, a cellular host defense responsive to foreign DNA (PubMed:18005698, PubMed:1602551).  Phosphorylates host BANF1 on serine and threonine residues; this leads to BANF1 relocalization to the cytoplasm, loss of dimerization and impaired DNA binding activity (PubMed:24600006).  Indeed, BANF1 activity depends on its DNA-binding property which is blocked by VPK1-mediated phosphorylation (PubMed:18005698).  Required for viral intermediate genes expression, probably by inhibiting host BANF1 (PubMed:11287554, PubMed:23891157).  Modulates cellular responses via host JUN by two different mechanisms, either by direct phosphorylation or by modulation of upstream JIP1-MAPK complexes (PubMed:16840345).  Seems to participate in the accumulation/processing of late proteins and thus in virion maturation (PubMed:26223647).  In addition, inhibits B12 repressive activity on viral DNA replication via a phosphorylation-dependent mechanism (PubMed:31341052).
What are the official names of this protein?
B1 kinase, Serine/threonine-protein kinase 1, Vaccinia protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.
Protein: AROA_HELPG
Sequence: MIELDINASDKSLSHRAVIFSLLAQKPCFVRNFLMGEDCLSSLEIAQNLGAKVENTAKNSFKITPPTAIKEPNKILNCNNSGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLKAFGAKILGREDNHFAPLAILGSPLKACDYESPIASAQVKSAFILSALQAQGISAYKENELSRNHTEIMLKSLGADIQNQNGVLMISPLEKPLEAFDFTIANDPSSAFFFALACAITPKSRLLLKNVLLNPTRIEAFEVLKKMGASIEYAIQSKDLEIIGDIYIEHAPLKAISIDQNIASLIDEIPALSIAMLFAKGKSMVKNAKDLRSKESDRIKAVVSNLKALGIECEEFEDGFYIEGLEDISPLKQHLSQKKPPLIQSFNDHRIAMSFAILTLALPLEIDNLECANISFPQFKRLLNQFKKGSFNGN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSR_HORSE
Sequence: MAQRWGPQKLAGGQPQAGFEDSTQASIFTYTNNNATRDPFEGPNYHIAPRWVYHVTSAWMIFVVIASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYFVLGHPMCVVEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAVAGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMITCCIIPLSVIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVMVMVFAFCLCWGPYTFFACFAAAHPGYAFHPLVAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLFGKKVDDSSELSSVSKTEASSVSSVSPA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Long-wave-sensitive opsin 1, Red cone photoreceptor pigment, Red-sensitive opsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL11_PSESM
Sequence: MAKKITAYIKLQVKAAQANPSPPVGPALGQHGVNIMEFCKAFNARTQGIEPGLPTPVIITVYSDRSFTFETKSTPASVLLKKAAGLTSGSARPNTVKVGTVTRAQLEDIAKAKNADLTAADMEAAVRTIAGSARSMGLNVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MCES_LODEL
Sequence: MPEDSYIPQAKNDGAFQDLKRRRANDGHTEFSRRDRVHDVQPASIYSNVKENKPAWMRSADENKDKKYDQYGSRVDNGTLQQSLGVAKQVPTASASTTTVSAKVESFSAEKAINTANPPPPSTTTTPSSTTSSSSSFPSSSSLYLKYGNIGLGGRGTDPRMDRVKRNREQLEQSLSIREHLAVEENVNDEGSQPKGDGEVNPYLHLDVANPSVIHTQRDEAHYRTFHSKISDRENRDINSIVRQHYNERTQQSKRQGRRTMSPIYKLRNFNNTIKYILLGNWAKYSSAEGNAPKIFSVLDLCCGKGGDLNKCEFIEIDQYIGIDISDLSVREAFSRYSKQKARFKSHSGARTANKYNFEACFATGDCFTETVPDILEPNFPGIIDQAFPVDAVSIQFALHYAFETEEKVRALLVNVAKSLRVGGTFIGTIPSSDFIRSKIVEKNILKDENGKFKFGNSLYSATFDKEPPADGVFRPAFGNRYTYWLKDAVDNVPEYVVPFETLRALCEEYNMTLRYKKNFIDVFNQEIPKYFSKLNKSLVEGLKRSDGKYGAEGEEKEAVAFYVAFVFEKVT
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ES1_RAT
Sequence: MAAVRVLVSPRLASALLPLSGRHRTTSQRAAIHSSAPRPRARVALVLSGCGVYDGTEIHEASAILVHLSRGGAEVHIFAPDVPQMHVIDHTKGEPSEKESRNVLAESARIARGKITNLAQLSAANHDAAIFPGGFGAAKNLSTFAVDGKDCKVNKEVERVLKEFHGAKKPIGLCCIAPVLAAKVIKGVEVTVGHEQEEGGKWPYAGTAEAVKALGAKHCVKGVTEAHVDQKNKVVTTPAFMCETELHHIHDGIGAMVKKVLELTGK
What are the official names of this protein?
ES1 protein homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ES1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FTHS_METLZ
Sequence: MGWKYLLSDIEIAQQCKMKKITEIAASLDITPDELELYGSYKAKLADSLEKRLADKPNGKLILVTAINPTPAGEGKTTTTVGLGQAMPKIGKKAVIALREPSLGPVFGVKGGAAGGGYSQVVPMEDINLHFTGDFHAITSANNLLCAMIDNHIQQGNALDIDTRRIIFKRCLDMNDRALRNIIIGLGGQTNGVPREDHFMITVASEVMAILCLANDIDDLKERLGNVIFGYSRKGTPLYARDLKAVGAMAALLKDAIKPNLVQTLENTPCFIHGGPFANIAHGCNSVRATKLSLKMADYVITEAGFGSDLGAEKFFDIKCRYAGLTPNTVVLVATVRALKYNGGVKKEDTTIPNVAALKAGMVNLEAHIQNLQTFGVPVVVAINRFSTDTDEELAVLKEFCTAQGAEFAISEVFAKGGEGGVELAKKVVASCEKPQKFQCLYELNTPIKEKINALATRIYGADGVVYSPAADAAIKDIDALGRSNLPICMAKTQYSLSDDPNKLGRPKNFVINAATVRLCNGAGFIVVETGDIMTLPGLPAVPAACSIDVNNDGYISGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: KEA5_ARATH
Sequence: MARFAVIGLTFLLLLGTSLSARSDEETRERFYGNVVNSTAPGNGEGSIAKMFDRVLEKEFSENDSPEGSDGASFNSSVADQQAEIETVAKVTHEKGKRNDTQENNGTRPFQLQDVFSLENEDSDDMTLIDKKNNVFVMSNKKSKYPILQVDLRLISDLVVIIVFAAIGGIVFSCLGQPVIVGYLLAGSIIGPGGLKFISEMVQVETVAQFGVVFLLFALGLEFSMTKLKVVGPVAVLGGLLQIVLLMFLCGVTALLCGARLSEGIFVGAFLSMSSTAVVVKFLVERNSTSSLHGQVTIGILIFQDCVVGLLFALLPVLGGNSGLLQGIISMGKLLLILSIYLTVASLLTWSFVPRFLKLMIQLSSQTNELYQLAAVAFCLLSAWCSDKLGLSLELGSFVAGVMLSTTEFAQHTLEQVEPIRNLFAALFLSSIGMLINVHFLWNHVDILLASVILVIVIKTAIAAVVVKAFRYNMRISFHVGVLLAQIGEFAFVLLSRASNLHVIEGKMYLLLLGTTALSLVTTPLLFKLIPSAMNLGVLLRWFPSENSSPNESLQEKASLIEVHNRTK
What is the function of this protein?
Electroneutral K(+)/H(+) efflux antiporter involved in K(+) homeostasis and osmotic adjustment (PubMed:24278440, PubMed:31296940, PubMed:30309966, PubMed:30255504).  Together with KEA4 and KEA6, promotes growth and development, and facilitates endosomal pH and ions homeostasis, as well as salt tolerance (e. g.  K(+), NaCl and LiCl), probably by supporting cell wall biosynthesis during rapid etiolated seedling growth (PubMed:30309966, PubMed:30255504).
What are the official names of this protein?
K(+) efflux antiporter 5, AtKEA5.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KEA (TC 2.A.37.1) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIS5_BACHK
Sequence: MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGCSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDSSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2001_PYRHO
Sequence: MLVIVGGTTTGILFLGPRYLPRYLPILGINGASAMKKSYFLANFLACLGLLAISSSSALLITSSPSLLAASATAPSAMTAIFTSFPLPWGSTTSSLNLFSGRLRSISLRFTATSTLCVKLRGLARALASFTASTIFCLSKAILDIPP
What are the official names of this protein?
Uncharacterized protein PH2001.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HXK2_TOBAC
Sequence: MSVTVSSPAGRSFHISRSPYKKISKPRVIIAAVRSGVSLAVAPILTKLQKDCATPLPVLRHVADAMAVDMRAGLAVDGGSDLKMILSYIDTLPTGNEKGLFYALDLGGTNFRVLRVQLGGKEERVIATEFEQVSIPQELMFATSEELFDFIASELGKFSQSEGGKFEMQQGRTREIGFTFSFPVKQTSVKSGILIKWTKGFAVSGTAGKDVVACLNEAMERQGLGMQVSALVNDTVATLAGARYWDNDVMVAVILGTGTNACYVERVDAIPKLPQRMSNSPETIVNTEWGAFSNGLPLTEFDREMDAESINPGEQIFEKTISGMYLGEIVRRVLVKMAKVGGLFGGGYVPEKLVTPFVLRTPDICAMQQDTSRDLEAVESVLYDIAGVKSDLSARKTVVDICDTIANRGGRLAGAGIVGILQKMEEDSKGVIFGKRTVVAMDGGLYEHYPQYREYLQEAVTELLGSEISKNVVIEHSKDGSGIGAALLAAANSKYEHDY
What is the function of this protein?
Fructose and glucose phosphorylating enzyme.
What are the official names of this protein?
Hexokinase-2, chloroplastic, NtHxK2.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: DTDA_PYRCJ
Sequence: MYVLVLSMGDPVSRTFLDVTGPMPLLKTVGNVEVRKYRDMPVVIHRGDPVEFGAEEVLASLGKWAIFISRHEMANPKPFLTVHTPGAWPDVSVSNPRLVSSLYRALCKVAEEPFDCAIEATHHPPNTSAVSATFLEVGSTEAEWNSRRAVGLLQAALEEAVKGGVEATPTMVIGDLHYTTVGDLVLKGDIDVGHIVPKYVEITLDVVRRAYEKHTVPIRRAILFRKNVKNPTRSEVVEFLKAKGVDVVLKG
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: MNTP_SALCH
Sequence: MHFTATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGLGILASKFVLEWNHWIAFVLLIFLGGRMIIEGIRGGSDEDETPLRRHSFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMIGRFIGPMLGKRAEILGGVVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAD_CLOPS
Sequence: MRVGVYPGSFDPITKGHLDLIERAASKFDKVIVAVLININKKGMFSIEERVNLIEKCVAKYNNVEVKSFNGLLIDFVRKEKADVIIKGLRSVTDFEYEFQMALMNRELANEVETVFMVTSPNYSYISSSAIKQVASFSGEIKNFVPKEIVEDLEERIISLRGEG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_RHOOB
Sequence: MPSLSLSKLLRVGEGRMVKRLKHIADHVSSLSPEVEDLTDEQLRAKTEEFRARYRDGETLDELLPEAFAVAREASWRVIDQRHFHVQIMGGAALHFGNIAEMKTGEGKTLTCVLPAYLNAIAGDGVHVVTVNDYLAKRDSEWMGRVHRFLGLDTSVILSGMSPAERRAAYAADITYGTNNEFGFDYLRDNMTHSLDDLVQRGHNFAVVDEVDSILIDEARTPLIISGPADASSKWYAEFARIAPLLKRDVHYEVDIRKRTIGVHEAGVELVEDQLGIDNLYEAANSPLVSYLNNAIKAKELYTKDKDYIVRDGEVIIVDEFTGRVLVGRRYNEGMHQAIEAKEKVEIKAENQTLATITLQNYFRLYDKLSGMTGTAETEAAELHQIYNLGVIPIPTNRPMVRVDNGDLIYKTEEAKFHAVVDDVVERHEKGQPVLIGTTSVERSEYLSKQFTKRGVAHNVLNAKFHEQEAQIIAEAGRSGAVTVATNMAGRGTDVVLGGNPDIIADIALRKQGLDPVHTPDDYEAAWDDVLDQVKAEVKADADKVREAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDELMRRFNGAALESIMTRLNLPDDVPIEAKMVSKAIKSAQTQVEQQNFEIRKNVLKYDEVMNQQRTVIYNERRQILEGKDMEGQVEKMITDVVTAYVDGATAEGYVEDWDLEQLWTALKTLYPIGVDYKELVGDGDDETKDITAEELRETLLKDAHDAYARREAEIDGVAGEGSMRELERRVLLSVLDRKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQREGFDMFGGMLEGLKEESVGFLFNLQVEAAAPQAAQAPGVSVTAASAAATASAAPAPAAPRPLPTQEAAQQAQGTAAPSALRAKGLDDGEPRGLTYSGPAEDGNAQLSRRGAAESDDSADAGTRRQRREAARSQSKGKKAPRTKRKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: Y2036_STAES
Sequence: MAKVKEKVAVVTGASSGIGEAIAKKLSQQGASIVLVGRNEQRLNEIAQQLNTPAKVVSADVTVKSNIDDMLKAVIDHFGHIDIVVNSAGQSLSSKITDYNVEQWDTMIDVNIKGTLHVLQATLPYLLKQSSGHIINLASVSGFEPTKTNAVYGATKAAIHAITQSLEKELARTGVKVTSISPGMVDTPMTEGTDFGERKKLEAQNIADAVVYALTQPSHVNVNEVTIRPV
What are the official names of this protein?
Uncharacterized oxidoreductase SE_2036.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: DCN1M_DICDI
Sequence: MTRKYTKKSSGSTASTTNSTAEIVDLTTSTSSVGKKRKSPDEKAQPITKKALNSLTPVQSMFEKYKGKNIIKAIHYTYLYTYIFNVHLDDDETIGPEGIARFCSDIGLAPDSFEILVLAWTMNASKMGYFSKNEFSSGFEKLQCSDLSTLKKQLNSTSQKLKHDSTKFTDLYKYAFGFASEVESKKSVDLGTAAEMLKLLLPEGPHTTNFAAFLCTQPNKSINKDQWLCFLEFSRTVKADLSNYDDSEAWPLLLDQFSEWVQQEKRI
What are the official names of this protein?
DCN1-like protein 2, Defective in cullin neddylation protein 1-like protein 2.
Protein: MOAC_BACCR
Sequence: MSSFTHFNDQGRAKMVDISDKKATVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLLLKGVDVSFDWKQSEEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRNS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RT10_PEA
Sequence: MTTKIRIVIRSFDHPFLENHFGGLPPYTWKIGLPESRVLYTVLRSPHIDKKSREQFEMEIKKKYLVIKTEKHELRKKFFWLKRQRLFGAQYEILFFCKTRSDKGKLQRLL
What are the official names of this protein?
Ribosomal protein S10, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPIA_ECODH
Sequence: MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIVK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: HMC1_METTE
Sequence: SNTRNFVLRDEDGNEHGVFTGKQPRQAALKAANRGSGTKANPDIIRLRERGTKKVHVFKAWKEIVDAPKNRPAWMPEKISKPFVKKERIEKLE
What is the function of this protein?
Protects DNA against thermal denaturation and modulates transcription.
What are the official names of this protein?
Chromosomal protein MC1.
Protein: CLPB_LISMO
Sequence: MDLQKFTQQVQQTIADAQNLAIASEHQEIDVAHVFKVLLTESDFAKRVYDVAEVDTDALQKVIENTLEKIPVVSGSGVNYGQAMSQALFQLMRDAEKEQQQLEDDFVSTEHLILAVMDQKSNPITAELKNQHKAKKQIKEAILKIRGGKRVTSQNAEENYEALTKYGRDLVAEVRSGKLDPVIGRDAEIRNVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPEGLKDKTIISLDIGSLIAGAKYRGEFEERLKAVLQEVKQSDGQILLFIDEIHTIVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLDEYRQYIEKDAALERRFQKVLVPEPTVEDTVSILRGLKERFEIHHGVNIHDNALVAAASLSNRYITDRFLPDKAIDLVDEACATIRVEIDSMPSELDEVTRKVMQLEIEEAALKEEKDPASERRLEILQRELADYKEEANQMKSKWESEKNEISKIREVREQIDHLRHELEEAENNYDLNKAAELRHGRIPAVEKELLELEAENREKTAQEDRILQEEVTENEIAEIVGRWTGIPVTKLVEGEREKLLKLADVLHQKVIGQDDAVQLVSDAVLRARAGIKDPKRPIGSFIFLGPTGVGKTELAKALAFNMFDSEDHMIRIDMSEYMEKHSVSRLVGAPPGYIGYEEGGQLTEAVRRNPYSIVLLDEIEKAHPDVFNILLQVLDDGRITDSQGRLIDFKNTVIIMTSNIGSNLLLERTEEGEISPELESDVMQILQSEFKPEFLNRVDDIILFKPLTLADIKGIVEKLVEELQIRLADQEITITISDDAKAFIAEEAYDPVYGARPLKRYIVRHVETPLAREIVSGKIMPHSSVEIDLADKEFTFKVTE
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).  Required for induced thermotolerance, but not for general stress survival.  Involved in virulence, maybe acting as a chaperone in a key process for pathogenic development.
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_MAGMM
Sequence: MQEARATTKYQRVSPYKVRLVIDQIRGMQVESAMNLLAFSKKRVAGVVRQTLKSAVANAEENLGLDVDTLVVSQAYVDQGPSMKRFKPRARGRATRILKRTSHITVAVCPQVD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.