PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_STRSY
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERDGLFDEVIFGPTKDWECSCGKYKRIRYKGITCDRCGVEVTRAKVRRERMGHIELKAPISHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLPKEIAALKEELKTASGQKRIKAVRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNELYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIAGNVKAAKRLIERGDDRIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDAGREGEGMVFKDADEAVMAYRNGYVHLHTRVGIATDSLDKPWKDNQKHKVMMTTVGKILFNAIMPEGLPYLQEPNNANLTEGTPDKYFLEPGSDIKAAIAELPINPPFKKKNLGNIIAEIFKRFRTTETSALLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEESHERVEQIKKQFRRGMITDDERYAAVTDEWRSAKEKLEKRLVEKQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMSAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLDIRSITDGKEMIEPLEERLQGRYTKKTVKHPETGAVIIGPNQLITEDIAREIVNAGVEQVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNSDITQGLPRVQEIFEARNPKGEAVITEVKGEVIAIEEDASTRTKKVFVKGKTGEGEYVVPFTARMKVEVGDQVARGAALTEGSIQPKRLLEVRDVLAVETYLLSEVQKVYRSQGVEIGDKHIEVMVRQMLRKVRVMDPGDTDLLMGTLMDITDFTDANAEVVIAGGIPATARPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKRDNLLGLKENVIIGKIIPAGTGMARYRNLEPQAINEVEIIEDTVAEELAAEAELEAVTE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PYRG_NEIMF
Sequence: MTKFIFVTGGVVSSLGKGIAAASIAAILESRGLNVTMLKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFIDSTMTRRNSFSTGQVYENVIAKERRGDYLGGTVQVIPHITDEIKRRIHEGAAGYDVAIVEIGGTVGDIESLPFLEAIRQMRSQLGRNNTLFAHLSYVPYIAAAGEIKTKPTQHTVKEMLSIGLQPDILICRMDRTMPADERRKIALFCNVEERAIVGSYDVDSIYECPEMLHDQGIDNIITEQLQLNVQQADLTAWKKIVHAIQNPKHTVKIAMVGKYVDLTESYKSLIEALKHAGIHTETDVQITFVDSESIEKNNGDVSMLKDMDAILVPGGFGSRGVEGKIAAVRYARENNVPYLGICLGMQIALIEYARDVAGLKGANSTEFDLKCAAPVVALIDEWQTADGSVETRDESADLGGTMRLGAQEVELKAGSLAAKIYGSEHIRERHRHRYEVNNNYVPTLEQAGLVIGGVSAGRERLVETIELPNHPWFFACQFHPEFTSNPRKGHPLFTAFVKAALNNKKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RF1_THEKO
Sequence: MSHKSAEMYELKKKVEELKSYRGRATELVSLYIPAGYDINKVMQQLREEYGTAQNIKSKSTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEQEGVSDIKLWAIVPPEPLNVRLYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVIDELTSNVPGKTRAGGQSARRYERIREQETHEFMKRIGEHANKAFLPLLEKGELRGIIIGGPGPTKEEFVEGDYLHHELRKKVIGVVDISYHGEYGLRELVEKASDILKDHEAVKERQLIQEFFKHLVKDTGMITYGEKEVRKALELGAVDKLLISEGYDKVRVRAKCNNCGWEELKTMSEGEFHVYKKQLTHCPKCGSQNITFEKWDVAEELIKMAEESGADVEIISLDTEEGQQFYKAFGGLGAILRYKIQ
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNC_RHIL3
Sequence: MFELKNVTRRFGKKLAVDSVTLAIAQGQMVGIIGRSGAGKSTLLRMINRLQEPSSGSVHFAGVEVSGLRGQALRNWQRDCAMIFQQFNLVPRLDVLTNVMLGRLNHRSTLMSLLNIFTREERVHAIAALERLGIEQTALQAAGTLSGGQQQRVAIARALMQNPKMVLADEPIASLDPLNAKIVMDALRDINEREGITVITNLHTLDTARNYCERIVGMAGGRVVFDGKPSELTAEAVKEIYGTDKDGAGIDETMTSTSLESKRRAEDVSSGRVAKAAAVH
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FTSL_PSYIN
Sequence: MSTPNTHLLCLIATDLRKHFFAVLVGMLIVCSAIYNVYTTHKTRGLVTQIERLAQDKDDLMMEWRNLLIEEHTLDEHSRIRRIALKKLSMSQATKKNSVLVELR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: DNAJ_ECOUT
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2C75_RAT
Sequence: MSRQSTVTFHSGSRRGFSTASATTPTAGRSRFSSVSVARSSGNSGGLGRISGIGSGFGSRSLYNLGATRPVSVGGCAGSGFRSGFGGRASSSFGYGGGFGGPGFPVCPSGSIQEVTVNQSLLTPLNLQIDPTIQRVRKEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQEQGSRTVRQNLEPFFDAYVNDLRRQLDSVTAERGRLDAELRHMQEVVEDFKVRYEDEINKRAAAENEFVGLKKDVDGAYMNKVELEAKVDSLTDQINFYRMVYEAELSQMQNQVSDTSVVLSMDNNRSLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRSEIDAVKKQCSSLQTAISDTEQRGELALKDARAKLVELEDALQKAKQDMARLLREYQELMNVKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTVSSGYGGGTNIGGGSLGLGGNSGYSFTTTGGHSLGTGLGGSGFTTSSSRGPVGSGSSIKFVSSTSSSRKSYKH
What is the function of this protein?
Plays a central role in hair and nail formation.  Essential component of keratin intermediate filaments in the companion layer of the hair follicle (By similarity).
What are the official names of this protein?
Keratin, type II cytoskeletal 75, Cytokeratin-75, CK-75, Keratin-6 hair follicle, Keratin-75, K75, Type II keratin-K6hf, Type-II keratin Kb18.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: Y809_SHEPA
Sequence: MKQHLWPLFLEAIKRDVVPALGCTEPISVALAAAIAIGELGIKNQASNVKMDVSVSANLMKNGMGVGIPGTGMVGLPIAAAIGAVAGDSNAGLEVLKNLTDSDVQAAKLMLDNGQVTVGVADVANVLYAKVTVYYQQQTASVTIADSHTKVIAIEKNGEQCLPAPEVESVNDKSNKANPFTEARLQDIYDFAMHAPLDDIGFIMQSKSLNDALSIEGLSGHYGLKIGATLVKNQEKGLLSGGLLTEVLARTAGASDARMDGAMMPAMSNSGSGNQGIAATMPVVACAEFLKSSETQTIRALMLSHLTAIYIKSYQNKLSALCGATTAAMGSAAGITYLLDGEIEQVSAAICSMIGDVSGVICDGAKTACAMKVSSSAGAAVKSALMAIDGIRVTGTEGIVADDVDQTISNLATLANGAMTQTDVQILEIMMHK
What are the official names of this protein?
UPF0597 protein Spea_0809.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: IE63_ALHV1
Sequence: MAQQAIVTMSALRRTMEVSDSGDVSIDISAEDSNDSFHLEESVDDCMDDCKPNNRPNPISMKPAKRRVFMVPKRERSKTPVQHTSPLNRLYPNVVLGKQHGYKQRPAPSARSRRPQPYSARKDSAAKPQSTPSNQNPLTELLKNVDPAIASRITEMRIPRSMLRTPSGQPFAHWLMPSAEDSSKFINVNPVNMEVEEHVNVVVRRCTEWALISSRLQDKSISTKYLAENFYDLRDFAQRSINKSAWINLRREAIANAGFVNLCAFADEMMMWLQLNLNNQGSWKACREDIILTGAPDMCFHALQKVRAFIKCFLRERHQRALVNALCHIICFEGGIKQAATLCQELFFDFKVGLMVLYFLTPYAFLYSHTIPQCNFGGYFSKCVAQYTPGAVTGLLNSAIEDHYKDCTSQDCTNLITAIVSPETSNKGLLFFPLPM
What is the function of this protein?
Acts at a post-transcriptional level to regulate viral gene expression.
What are the official names of this protein?
Immediate-early phosphoprotein 57.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL69 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Shuttles between the host nucleus and cytoplasm.
Protein: TSR3_SCHPO
Sequence: MGPRSSNRRSNAKDGFKGSNKASKFPLPLAMWDFGHCNPNACSGKRLERLGCVRNLRIGQKFRGVVITPNGKVPVSPADKEYFDNGGASVVECSWARIEEIPFSRIGGRCERLLPYLVASNPVNYGRPWRLNCAEALAACMYIVGYPNEARLLMDNFKWGHSFFEVNEELLDIYAQCHDAQDIQEKEKKYLEEMEASYQEQRNQTTDDIWSAGNLNHKPTLNTSSTHSNSEESRSPLHEPSEASLAHDEHSIPTDDNEETLTNLQANDVDEDEVWRKIVRMKVHSTDT
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA.  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.  Required for processing 35S pre-rRNA at site D.
What are the official names of this protein?
18S rRNA aminocarboxypropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS12_SYNP6
Sequence: MPTIQQLIRDEREKITKKTKSPALKNCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGTLDTAGVKDRRQSRSKYGAKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: OBG_HELPJ
Sequence: MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRGTKHHKAKNGAPGGTRNCAGKKGEDKIIVVPPGTQVFVGDELWLDLVEPKERVLALKGGKGGLGNAHFKSATKQQPTYAQKGLEGVEKCVRLELKLIADIGLVGFPNAGKSTLISTISNAKPKIANYEFTTLVPNLGVVSVDEKSEFLMADIPGIIEGASEGKGLGISFLKHIERTKVLAFVLDASRLDLGIKEQYKRLRLELEKFSPTLANKPFGVLLNKCDVVENINEMTKDFCAFLNLEAQKLNAFDLEPYLGFLHPNLTSDFENNPNEQSALFVLPLSAVSALNTHALKFVLLKALQ
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG060_VACCP
Sequence: MRSIAGLHKLKMEIFNVEELINMKPFKNMNKITINQKDNCILAYRCFVKIDTPRYIPSTSISSSNIIRIRNHDFTLSELLYSPFHFQQPQFQYLLPGFVLTCIDKVSKQQKECKYCISNRGDDDSLSINLFIPTINKSIYIIIGLRMKNFWKPKFEIE
What are the official names of this protein?
Protein OPG060, Protein F15, Protein F2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG058 family.
Protein: AL1A2_RAT
Sequence: MTSSEIAMPGEVKADPAALMASLQLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
What is the function of this protein?
Converts retinaldehyde to retinoic acid.  Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal.  Can metabolize octanal and decanal, but has only very low activity with benzaldehyde, acetaldehyde and propanal.  Displays complete lack of activity with citral.
What are the official names of this protein?
Retinal dehydrogenase 2, RALDH 2, RalDH2, Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH(II).
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPB_SULTO
Sequence: MSWHQAVWNEPLIFEYKGKGRIGFKIPEEEELKKEISINIPEKLRRKEIDLPELSELEVIRHFIRLSQMSFGVDNGMVPLGSCTMKYNPKIEEEAELLTQNLHPLQDDSTVQGILEVLYYMQKWLAEITGMDLCSLQVPAGAAGELAGVLMIKKYHETKGRGNRDEMLVADTAHGTNPASASMENFKVIYIKSNSEGLVDVDILKEIVSERTAGFMLTNPNTLGLFEENILDIAKYIHSVDAKLYYDGANLNGILGVVRPGDMGFDIVHLNLHKTFAVPHGGGGPGAGAICAKGEMVNFLPYPLVEKKDGKYSLSYIPKYSIGKIATFYGNVGNVVRAYTYILGLGAEGISMIGKMSTLATNYLISQLKNVRGLELIAPYRPRKHEVVFSAKTLAKETGVTANDVAKALLDRGFYAPTIYFPPNVEEALMIEPTETEPKEVLDSFAIAIKEIINTAYSNPKEILDTPKNTSVKRLDQVIANHPSSVTPTYRVKRLREEGKIGSLK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: PSB_PICTO
Sequence: MEVLKTGTTTVGITAGDYVIMGTDSRATMENFISNKNAQKLYQIDNYAAMTIAGLVGDAQVLVRYMKAEMELYRVQRKVSMPIDAAATLLSNMLNQTKFYPYMVQLLVGGYDTKPHIFSIDAAGGSVEDIYASTGSGSPFVYGVLEAEYQKNMSLDDGINLVIKAISAAKQRDSASGNMLQLGVVDPKKGFYYLSEDEILSRLKKLKLQL
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_HELPG
Sequence: MSKALLRFVRLSPTKARLIARQIQGMNAELAIASLEFTPNKAARVLSKVVASAVANGSLDAKSTLIVSCRVDAGPVLRRSIPRAKGRATAIRKPTSHVFVEVAEGKEMKSSKSHKKNQAEGK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TYPH_ECOHS
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENSWQDAAKAVKAAIKLADKAPESTPTVYRRISE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: RNZ_STAA9
Sequence: MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQILIQNEDTPNFNFVKDFDSFKV
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: URE3_YERKR
Sequence: MQLTPREVEKLMIYTLSDVAFKRKARGLKLNYPEAVSIITVTAMEGARDGKSVEDVMKEASKVLTKDDVMDGVADLIPNVQVEAIFTDGSRLVTVHDPIK
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y123_DESVH
Sequence: MSQNVISQPVEAQQSFARAVTESLPGLLLVCAVALVASFVAPKLEAYPLFKTYLSLKDFILAIIFGIIIRNTVGVPAVFQPGLRYSTIMTKTGIVIMGSSYSLAGLVSVGAQALVFIAVFLFGTALVMMWLCRKVGMSTPLAACLAAGMSVCGVSATIAIAPAVKAKNEDMAYSIAVVLMFGLLALIAFPLIGKVFNLTPEQFGAFAGVGIVNSAQVLAAGFGFSQEAGIVAGIYNIGRVVFLPFVVLMLAIMAAAQEAEQGNEVAKINKWQMIRDKFPLFVLGFLAIVCLNTAGVLTKPEVKMAKHFMEWAFLLGFASIGLTTRLSDLRAAGLNGFLFGFGVAGLKAALALAAVLLFMS
What are the official names of this protein?
UPF0324 membrane protein DVU_0123.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CREBA_DROME
Sequence: MEFYDGDLKDIWDSDLDPESLKISPDHDMHDWLFDRDVKDPTVILNDKLISDALLNGTQPIKTEHSYSLSSDVDSLPDSPKSLQAKIEDMDDECFPAISPKTATNGRVTIDPKYLTFHVPPTHATPISRLSSNPALNTSVADLTRSSGLQSLQAHQPHHGSGSSHVVVANLEHFQLPQHLYDNDCSSSVSSLRDGSMSPDICSDIEIDESAIKDEPMSPDSSCPASPTSQASSSQHQLSLNLAHLQSEMLFEPKHCGLLLTASSNSNNSLIKSQQRQQQILGQDNLLMAKMEIKSEKQSTSNSSDKSHAHGYGIPLTPPSSLPSDDSEGNLSPEHLFAPLSPNATVSISVANPAGGESSVRVSRTAASITRSSSGSASASGSSTSSTVTTTRQPIHTPLISSQPKGSTGTLLLTEEEKRTLLAEGYPIPQKLPLTKAEEKSLKKIRRKIKNKISAQESRRKKKEYMDQLERRVEILVTENHDYKKRLEGLEETNANLLSQLHKLQALVSKHNVKKS
What is the function of this protein?
Transcriptional activator.  Binds to fat body-specific enhancers of alcohol dehydrogenase (ADH) and yolk protein genes.  BBF-2 may play a role in fat body gene expression.  It binds the consensus sequence 5'-T[AC]NACGTAN[TG]C-3'.
What are the official names of this protein?
Cyclic AMP response element-binding protein A, cAMP response element-binding protein A, dCREB-A, Box B-binding factor 2, BBF-2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAU8_YEAST
Sequence: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN
What are the official names of this protein?
Seripauperin-8.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
Protein: MNMG_PSEPW
Sequence: MDFPSRFEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGHMSCNPAIGGIGKSHLVKEIDALGGAMALATDKSGIQFRVLNNRKGPAVRATRAQADRAIYKAVVREILENQPNLWIFQQSCDDLIVEQDQVKGVVTQMGLRFFADSVVLTTGTFLGGLIHIGLQNHSGGRAGDPPSIALAHRMRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFMGNAAMHPRQVSCWITHTNARTHEIIASNLDRSPMYSGVIEGVGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDVQLELVRSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRESWCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLIDDQRWAAFCAKRDGIEREEQRLKSTWVRPNTPQGQAVVDKFGTPLSHEYSLLNLLARPEVDYAGLIEATGGEQIDPQVAEQVEIKTKYAGYIDRQQDEIARLRASEDTCLPVDIDYTSISGLSKEIQGKLGQTRPQTLGQASRIPGVTPAAISLLLIHLKKRGAGRELEQSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRD1_MYCTO
Sequence: MSVHATDAKPPGPSPADQLLDGLNPQQRQAVVHEGSPLLIVAGAGSGKTAVLTRRIAYLMAARGVGVGQILAITFTNKAAAEMRERVVGLVGEKARYMWVSTFHSTCVRILRNQAALIEGLNSNFSIYDADDSRRLLQMVGRDLGLDIKRYSPRLLANAISNLKNELIDPHQALAGLTEDSDDLARAVASVYDEYQRRLRAANALDFDDLIGETVAVLQAFPQIAQYYRRRFRHVLVDEYQDTNHAQYVLVRELVGRDSNDGIPPGELCVVGDADQSIYAFRGATIRNIEDFERDYPDTRTILLEQNYRSTQNILSAANSVIARNAGRREKRLWTDAGAGELIVGYVADNEHDEARFVAEEIDALAEGSEITYNDVAVFYRTNNSSRSLEEVLIRAGIPYKVVGGVRFYERKEIRDIVAYLRVLDNPGDAVSLRRILNTPRRGIGDRAEACVAVYAENTGVGFGDALVAAAQGKVPMLNTRAEKAIAGFVEMFDELRGRLDDDLGELVEAVLERTGYRRELEASTDPQELARLDNLNELVSVAHEFSTDRENAAALGPDDEDVPDTGVLADFLERVSLVADADEIPEHGAGVVTLMTLHTAKGLEFPVVFVTGWEDGMFPHMRALDNPTELSEERRLAYVGITRARQRLYVSRAIVRSSWGQPMLNPESRFLREIPQELIDWRRTAPKPSFSAPVSGAGRFGSARPSPTRSGASRRPLLVLQVGDRVTHDKYGLGRVEEVSGVGESAMSLIDFGSSGRVKLMHNHAPVTKL
What is the function of this protein?
DNA-dependent ATPase, acting on dsDNA with a 3'-ssDNA tail, unwinding with 3'-to 5'-polarity.  A minimal tail of 18 nt is required for activity.  Also highly efficient on nicked DNA.  Involved in the post-incision events of nucleotide excision repair, as well as in nitrosative and oxidative stress response and possibly in persistence in the host.  Inhibits RecA-mediated DNA strand exchange; this does not require ATPase activity.  When combined with UvrA greatly inhibits RecA-mediated DNA strand exchange (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase UvrD1, DNA 3'-5' helicase UvrD1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: Y2049_STRCO
Sequence: MTSEAVRRVQSGSPWEESFGFARAVAAGDRVIVAGTTAFKGDMLYGEGDPYEQTKVAFGTAVEAIAEFGLGIESVIRTRVCLAHSRDVDAVGRAHKELFDSVRPVTTLLVVQGFIDSRVLVSVEVEAYRGAVDS
What are the official names of this protein?
Uncharacterized protein SCO2049.