PharMolix/UniProtQA huggingface dataset:
Protein: SSR2_HUMAN
Sequence: MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
What is the function of this protein?
Receptor for somatostatin-14 and -28.  This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.  In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins.  Inhibits calcium entry by suppressing voltage-dependent calcium channels.  Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion.  Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B.  Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development.  Mediates negative regulation of insulin receptor signaling through PTPN6.  Inactivates SSTR3 receptor function following heterodimerization.
What are the official names of this protein?
Somatostatin receptor type 2, SS-2-R, SS2-R, SS2R, SST2, SRIF-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Located mainly at the cell surface under basal conditions. Agonist stimulation results in internalization to the cytoplasm.
Protein: LMNA_XENLA
Sequence: METPGQKRATRSTHTPLSPTRITRLQEKEDLQGLNDRLAVYIDKVRSLELENARLRLRITESEDVISREVTGIKSAYETELADARKTLDSVAKERARLQLELSKIREEHKELKARNAKKESDLLTAQARLKDLEALLNSKDAALTTALGEKRNLENEIRELKAHIAKLEASLADTKKQLQDEMLRRVDTENRNQTLKEELEFQKSIYNEEMRETKRRHETRLVEVDNGRQREFESKLADALHELRAQHEGQIGLYKEELGKTYNAKLENAKQSAERNSSLVGEAQEEIQQSRIRIDSLSAQLSQLQKQLAAREAKLRDLEDAYARERDSSRRLLADKDREMAEMRARMQQQLDEYQELLDIKLALDMEINAYRKLLEGEEERLRLSPSPNTQKRSARTIASHSGAHISSSASKRRRLEEGESRSSSFTQHARTTGKVSVEEVDPEGKYVRLRNKSNEDQSLGNWQIKRQIGDETPIVYKFPPRLTLKAGQTVTIWASGAGATNSPPSDLVWKAQSSWGTGDSIRTALLTSSNEEVAMRKLVRTVVINDEDDEDNDDMEHHHHHHHHHHDGQNSSGDPGEYNLRSRTIVCTSCGRPAEKSVLASQGSGLVTGSSGSSSSSVTLTRTYRSTGGTSGGSGLGESPVTRNFIVGNGQRAQVAPQNCSIM
What is the function of this protein?
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
What are the official names of this protein?
Lamin-A.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope.
Protein: HSLU_ECO7I
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQTITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SA155_YEAST
Sequence: MSFWPFGQNLNHSNINKILDEYFHVLHELERINPSVGKAIPAIFNNVQERGTSDSLDSIPEEYSHGDEVKTARGDQKSRFEKDDQQERYEKEEEERSMNSSESSTTSFSSGSTSKTDLDEEDISNATAPMMVTTKNLDNSFIERMLVETELLNELSRQNKTLLDFICFGFFFDKKTNKKVNNMEYLVDQLMECISKIKTATTVDLNNLIDYQEQQQLDDSSQEDVYVESDTEQEEEKEDDNNSNNKKRRKRGSSSFGNDDINNNDDDDDANEDDESAYLTKATIISEIFSLDIWLISESLVKNQSYLNKIWSIINQPNFNSENSPLVPIFLKINQNLLLTRQDQYLNFIRTERSFVDDMLKHVDISLLMDFFLKIISTDKIESPTGIIELVYDQNLISKCLSFLNNKESPADIQACVGDFLKALIAISANAPLDDISIGPNSLTRQLASPESIAKLVDIMINQRGAALNTTVSIVIELIRKNNSDYDQVNLLTTTIKTHPPSNRDPIYLGYLLRKFSNHLSDFFQIILDIENDANIPLHENQLHEKFKPLGFERFKVVELIAELLHCSNMGLMNSKRAERIARRRDKVRSQLSHHLQDALNDLSIEEKEQLKTKHSPTRDTDHDLKNNNGKIDNDNNDNDDESDYGDEIDESFEIPYINMKQNIKLRTDPTVGDLFKIKLYDTRIVSKIMELFLTHPWNNFWHNVIFDIIQQIFNGRMDFSYNSFLVLSLFNLKSSYQFMTDIVISDEKGTDVSRFSPVIRDPNFDFKITTDFILRGYQDSYKFYELRKMNLGYMGHIVLIAEEVVKFSKLYKVELISPDIQVILQTEEWQYYSEEVLNETRMMYSKILGGGSYIDDGNGNIIPQLPDNTTVLTPNGDASNNNEILDSDTGSSNGTSGGGQLINVESLEEQLSLSTESDLHNKLREMLINRAQEDVDNKNTENGVFILGPPEDKNSNSNINNTNHNSNNSNNNDNNDNNDNDNDNTRNYNEDADNDNDYDHE
What is the function of this protein?
Positive regulator of protein phosphatase SIT4.  Involved in directing expression of TOR-repressed genes and in dephosphorylation of NPR1 in response to nutrient starvation.  Negatively modulates K(+) efflux of the cell by the Na(+)-K(+)/H(+) antiporter NHA1.
What are the official names of this protein?
SIT4-associating protein SAP155.
What is the protein family that this protein belongs to?
Belongs to the SAPS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_MYCPA
Sequence: MSKRSKAYRAAAEKVDRDNLYTPLQAAKLAKETSSTKQDATVEVAIRLGVDPRKADQMVRGTVNLPHGTGKTARVAVFAVGEKAEQAQAAGADIVGSDDLIEKIQGGFLDFDAAIATPDQMAKVGRIARVLGPRGLMPNPKTGTVTPDVAKAVADIKGGKINFRVDKQANLHFVIGKASFDEKALAENYGAALDEVLRLKPSASKGRYLKKITVSTTTGPGIPVDPSITRNFAEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CYAF_AMAPH
Sequence: MSDINATRLPIVGILGLPCIGDDVNSTLTHGEDLC
What is the function of this protein?
Cyclic octapeptide that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:27978833).  Cycloaminide E is structurally related to other cycloamanides that are non-toxic to mammals but show immunosuppressive activity (PubMed:27978833).
What are the official names of this protein?
Cycloamanide F proprotein.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: FABH_SODGM
Sequence: MFTKILGTGSYLPAHIRSNADLEKMVDTSDEWIVTRTGIRERRIARADETVSSMGRDAAEQALTMAGIAVQKVGMIIVATTSSSHAFPSSACQIQRELGINDCIAFDLAAACAGFSYALSVADNYIKNGAVEYALVVGSDALSHTLDPEDRGTLILFGDGAGAAVLGRSAEPGIISTHLHADGHYGDLLTLPYHNRLDPAASAYLTMSGNEVFKVAVTELAHIVDETLSANGLDRSELDWLVPHQANLRIITATAKRLGMGMEKVVVTLDRHGNTSAASVPLALDEAVRDGRIQPGHLVLLEAFGGGFTWGSALLRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_STAA3
Sequence: MNIEEFDYDLPESLIAQTPLKDRDHSRLLVMDRETGEMKHLHFKDIIEYFRPGDTLVLNDTRVMPARLFGLKEETGAKVEMLMLTQIEGNDWEVLLKPAKRIKVGNKLNFGNGKIIAECIKEMDQGGRIMRLHYEGILQERLDELGEMPLPPYIKERLDDPDRYQTVYAKESGSAAAPTAGLHFTDELLIEIKNKGVNIAFVTLHVGLGTFRPVSVDDVNDHEMHSEYYQMTQETADLLNDTKSKGHRIISVGTTSTRTLETIRRDHDKFVETSGWTNIFIYPGFDFKAIDGQITNFHLPKSTLVMLVSAFSSRENVLNAYKTAVNLEYRFFSFGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPI17_YEAST
Sequence: MSNANLRKWVGFCFVAIYLFLGVPLWYKLTTVYRASLPINYIESLQNNKFQDIHLVIPVYVKSDTYRFPDVHDAIQVQVNHLLNSQEQRVPWSLQVLPYNETIEQMESEGNQFHVVTLKLDEFIGYSSAYDTKETLVYYDDAAVLSNDLPFFVAQTLVEHTFQLEWTHLNKTCEGVSTNNDVAISYDPNIHLSVTLLSGDGNPVAWEIEPTLTDYFSPFRKFLSPLVNFTVDSSIVYHNDLNLHSLNGSCTSVTWFDLSHTIDLSELSSMAYYPEDSALNLAIVFPSASSSPDGLAFINGTRISDEITTLDWNSYLVPQWGVIIINKMPLKPNSVISEDYLEPMMYRFATDIFQLLGLTEGSQDLLSPYITIDSFKRLTILQNLDKATETLWSLVKLTQQFQGMSIPREVSDNVIEALDLRLQIIDLLNDPGKGGDIVWNNALHLSNELVKLCEKAFFNGEMVQQNFFPQEHMIAVYLPLLGPISAVMFFGFYNVMKEKNQKSKKNGTEREVAKEKLELKEAQKLHAIDGEDEL
What is the function of this protein?
Component of the GPI transamidase complex.  Involved in transfer of GPI to proteins.
What are the official names of this protein?
GPI transamidase component GPI17.
What is the protein family that this protein belongs to?
Belongs to the PIGS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HIRA_HUMAN
Sequence: MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKSAATREMGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSGSLAGTMLSSHSSPQLLPLDSSTPNSFGASKPCTEPVVAASARPAGDSVNKDSMNATSTPAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSMTPTAVERLKEQNLVKELRPRDLLESSSDSDEKVPLAKASSLSKRKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPAALTAEKEAMCLSAPALALKLPIPSPQRAFTLQVSSDPSMYIEVENEVTVVGGVKLSRLKCNREGKEWETVLTSRILTAAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTLHCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK
What is the function of this protein?
Cooperates with ASF1A to promote replication-independent chromatin assembly.  Required for the periodic repression of histone gene transcription during the cell cycle.  Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
What are the official names of this protein?
Protein HIRA, TUP1-like enhancer of split protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Note=Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence.
Protein: PLSY_FRATH
Sequence: MNFLNFSILIFAYLLGSINSAIIVCYIFRLPSPRSVGSGNPGTTNVLRIGGKVPAAITLIFDILKGLVPVVIAKVLTGNDFITACTALYAILGHIFPIFFGFKGGKGVATLIGTLFGFSWILGLIFVITWLCVAIITRYSSLSALVATVIASFSVIFTSDLQVAAPFLIIAIIILVKHKGNIQRLISGQESKIGDKAKAKNDSN
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP355_ARATH
Sequence: MYLPEKSVLLELISRCSSLRVFKQIQTQLITRDLLRDDLIINKVVTFLGKSADFASYSSVILHSIRSVLSSFSYNTLLSSYAVCDKPRVTIFAYKTFVSNGFSPDMFTFPPVFKACGKFSGIREGKQIHGIVTKMGFYDDIYVQNSLVHFYGVCGESRNACKVFGEMPVRDVVSWTGIITGFTRTGLYKEALDTFSKMDVEPNLATYVCVLVSSGRVGCLSLGKGIHGLILKRASLISLETGNALIDMYVKCEQLSDAMRVFGELEKKDKVSWNSMISGLVHCERSKEAIDLFSLMQTSSGIKPDGHILTSVLSACASLGAVDHGRWVHEYILTAGIKWDTHIGTAIVDMYAKCGYIETALEIFNGIRSKNVFTWNALLGGLAIHGHGLESLRYFEEMVKLGFKPNLVTFLAALNACCHTGLVDEGRRYFHKMKSREYNLFPKLEHYGCMIDLLCRAGLLDEALELVKAMPVKPDVRICGAILSACKNRGTLMELPKEILDSFLDIEFEDSGVYVLLSNIFAANRRWDDVARIRRLMKVKGISKVPGSSYIEKFMTLDQ
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g38010.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: CYB_PHYBN
Sequence: MTIMRKNHPLLKLVNNSFIDLPTPSSISSWWNFGSLLGVCLIMQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICMFIHVGRGIYYGSYMLSETWNIGIILLLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAFVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDLLGVLLLLMVLMILVLFFPDVLGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLALFPLINSSKQHGLVYRPITQIIYWIFIANLIILTWVGGQPVEYPFTMIGQIASIMYFSIIIIFMPMASMIENDILKLHY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSCL_LEUCK
Sequence: MLSEFKTFIMRGNVLDLAVGVIIGGAFTGIVKSLTNNLISPIITFFTGGTSDLQNLKLVVTKELTFKYGAFLNDVINFLITAFVVFLLVKFVNRILRTNKKEEVKANPELEVLAEIRDLLEAQKKA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCY1_ARATH
Sequence: MITVSEVSSYSSSSSNFASLSRLNHKSSSRLRSSSLYKGSFFSVSTKTRRNTCKAKSWNLGLVINSRSSEASVFDPLGINPDETSGLSSIWESFVSLLSPSFESSSGNRRDKPSSGRGVAAAIEDSSIDFGDFFKGPLPGKFLKLLGFLALSRLGIYIPLGGVNREAFVGNLDQNSILSTLDTFSGGGIGRLGICSLGIVPFINAQIVFQLLAQVYPKLQDLQKKEGEAGRKKILQYTRYASVGFAIVQAIGQVFYLRPYVNDFSTEWVVSSVTLLTLGSVLTTYIGERISDLKLGNGTSLLIFTSIISYLPASFGRTTAEALQEGNYTGLGTIVVSFLLLVLGIVYVQEAERKIPLNYASRYTSKAGGLQKSAYLPFKVNSAGVMPIIFSTSSLALPATLARFTGISALKNVAFALTPGGSFYLPTNILLIAFFNYYYTFLQLDPDDVSEQLKRQGASIPLVRPGKSTALFIKTVLGRISVLGSAFLAVLAAGPAVVEQITHLTAFRGFAGTSVLILVGCATDTARKVQAEIISQKYKNIEFYELDKYDP
What is the function of this protein?
Involved in protein export.  Probably interacts with other proteins to allow the translocation of proteins across the chloroplast thylakoid membranes.  Required for normal greening during embryogenesis.  Central subunit of the protein translocation channel SecYE.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug (By similarity).
What are the official names of this protein?
Preprotein translocase subunit SCY1, chloroplastic, CpSecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KCY_ECOL5
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_PETMA
Sequence: MLSLVLCFFVMFLLGVAVVVLSPSPYFSALGLVFVAVSGCFIVLYHGGTFLSLVLVLLYLGGMMVVFVYSAALAADPYPEVLGGRVIWFFVICVLCICFAGYMSFNDFFLDVSVACEGADYTGGIFGAEWLGVTTFYEVGLILVLAGWALLVCLFSVLVVVRGVNRGALRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: BISC_CERSP
Sequence: MGVEPFAHDPAPSELIHSVPACGSPERRVMRPMVREGWLADRQHSDRRGRGRERFLPVSWDAALDLVAGEIRRVSADHGNAAIFAGSYGWTSCGRFHHASTLLKRMLNLVGGFTGHVDTYSIAAGPVILRHTLGDDRACGGQANTLDSIAEHSQTLVVFGAMSPRTAQSEAGGIGAHHLETYLRRIVERGVRVILVSPLKDDLPDWVAAEWWPIRPNTDTALMLGLAGEIVRSGRQDSDFLARCTSGSELYLAYLRGEGDGRPKDAEWASTITGLPAEAIRALAGDLPRTRSMLTVSWSLQRAHHGEQPFWAALGLAAVIGQIGRPGGGVGYGYGSLGGVGAPFTIGKSPAMSQLSKPINSFIPVARISDMLLNPGGPYSYEGEDRRYPDIRLVYWSGGNPFHHHQDLNRLSEAWTRPETIIVQDPMFTATAKRADIVLPASTSIERNDLAGNKRSDFILAMGQAIAPLGEARSDFDIFNALSGKLGVAAAFNEGRDEMGWIRHLYEESRNHAQRHHHFEMPDFETFWAQGHAPCPVQRDHTYLAAFREDPGAHPLDTESGLIVLGSATLARLGYADCGPHPAWIEPAEWLGKAQAGELHLISHQPKGRLHSQLETAEASLAGKREGRDEVMLHPDDASVRGIADGQTVRLWNARGACLATAQVTDSVAAGVAILPTGAWFTPAEAEGPELSGNPNVLTLDIGSSAFGQGCSAHTCLVRIEAHAGDAGDAVRIYDAHLAAILPT
What is the function of this protein?
This enzyme may serve as a scavenger, allowing the cell to utilize biotin sulfoxide as a biotin source.  It reduces a spontaneous oxidation product of biotin, D-biotin D-sulfoxide (BSO or BDS), back to biotin (By similarity).
What are the official names of this protein?
Biotin sulfoxide reductase, BDS reductase, BSO reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
Protein: GRP2_NICSY
Sequence: MAEESGQRAKGTVKWFSDQKGFGFITPDDGGEDLFVHQSGIRSEGFRSLAEGETVEFEVESGGDGRTKAVDVTGPDGAAVQGGRGGGGGGGGRGGGGYGGGSGGYGGGGRGGSRGYGGGDGGYGGGGGYGGGSRYGGGGGGYGGGGGYGGGGSGGGSGCFKCGESGHFARDCSQSGGGGGGGRFGGGGGGGGGGGCYKCGEDGHFARECTSGGR
What are the official names of this protein?
Glycine-rich protein 2.
Protein: RLMF_ECOL5
Sequence: MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDT11_ORYSI
Sequence: MASVASSTVFASSLPHHRATTRAPPTPPRIPRRARLPGRSVVSCLPKRGSEKLVVTRASDEEGPPEPAGQGRGGGRAWPSLDASSCGLALAAAAGVLMLQGSQQALAGTEFMGMQDVVGDLGDISTGFASAFLLIFFSELGDRTFFIAALLAARNSGAIIFLGTFGALAVMTIISVVLGRAFHYVDGIIPFSFGGTDFPVDDFLAACLLVYYGVTTLLDAASGDEEKMNEEQEEAELAVSKFLGNGAGIISAASTIASTFVLVFIAEWGDKSFFSTIALAAASSPLGVIAGSLAGHAVATLIAVLGGSLLGTFLSEKIVAYIGGSLFLAFAAVTLVEIVNS
What are the official names of this protein?
GDT1-like protein 1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the GDT1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: PRVB2_MERCP
Sequence: AFSGILAEADIAAALKACEAAGTFNYKAFFAKVGLTGKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDDETKAFLKAGDSDGDGAIGVEEWAALVKA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta 2.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: MUTL_AGRRK
Sequence: MTIKQLSETLINQIAAGEVIERPASAAKELIENALDAGATRIEIATAGGGKALLRVSDNGSGMEQADLELAIKRHCTSKISDTLDDIRTLGFRGEALPSIGSVARLSIASRRVGSAGGAEIAVAGGKVLHLRPAAANPGTIVEVRDLFFATPARLKFLKTEKAEAAAITEVVKRMAIAFPQVRFVLSGSDRSTLEFPATGDDRLARMAQVLGKDFKDNAIELDAEREDVRLTGFAGVPTFNRGNSAHQYAFVNGRPVQDKLILSAIRGAYAETIPSGRYPIAVLSITLDPALLDVNVHPAKSDVRFRDPGLVRGLIVGAIREALAREGDRAATTGADGMLRAFTSGFQPGWRPSAPSAPWTPEASPSRPYQPAVTNGYSFRERPQAAFDGLTMPTARAESTPFVEPTQSEEPARFPLGAARAQLHENYIVAQTDDGLVIVDQHAAHERLVFEEMRKALHSKRLSSQVLLIPEIVDLPEEDCDRLMVFADELGELGLAIERFGPGAIAVRETPAMLGEVDAQGLIRQLADEIAEWDTASGLAAKLEYVAATMACHGSVRSGRRLRPEEMNALLRQMEATPGSGQCNHGRPTYIELKLSDIERLFGRS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SC6A2_BOVIN
Sequence: MLLARMNPQVQPENGGAGPGSEQPPRKRKEVLVVKERNGVQCLLASRDGDEQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTPTLPWTDCGHAWNSPNCTDPKLLNSSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLIIVVIVLFFSLWKGVKTSGKVVWITATLPYLVLFVLLVHGITLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAIVFFIMLLALGIDSSMGGMEAVITGLADDFQVLKRHRKLFTFAVSFGTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVIVSIINFKPLTYDDYIFPLWANWVGWGIAGSSMVLVPAYIVYKFFSTRGSIRERLAYGITPASEHHLVAQRDIRQFQLQHWLAI
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (PubMed:8150077).  Can also mediate sodium- and chloride-dependent transport of dopamine (By similarity).
What are the official names of this protein?
Sodium-dependent noradrenaline transporter, Norepinephrine transporter, NET, Solute carrier family 6 member 2.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.