PharMolix/UniProtQA huggingface dataset:
Protein: PGRP4_HUMAN
Sequence: MLPWLLVFSALGIQAWGDSSWNKTQAKQVSEGLQYLFENISQLTEKGLPTDVSTTVSRKAWGAEAVGCSIQLTTPVNVLVIHHVPGLECHDQTVCSQRLRELQAHHVHNNSGCDVAYNFLVGDDGRVYEGVGWNIQGVHTQGYNNISLGFAFFGTKKGHSPSPAALSAMENLITYAVQKGHLSSSYVQPLLGKGENCLAPRQKTSLKKACPGVVPRSVWGARETHCPRMTLPAKYGIIIHTAGRTCNISDECRLLVRDIQSFYIDRLKSCDIGYNFLVGQDGAIYEGVGWNVQGSSTPGYDDIALGITFMGTFTGIPPNAAALEAAQDLIQCAMVKGYLTPNYLLVGHSDVARTLSPGQALYNIISTWPHFKH
What is the function of this protein?
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria.  Has bactericidal activity towards Gram-positive bacteria.  May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis.  Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria.  Plays a role in innate immunity.
What are the official names of this protein?
Peptidoglycan recognition protein 4, Peptidoglycan recognition protein I-beta, PGLYRPIbeta, PGRP-I-beta, Peptidoglycan recognition protein intermediate beta.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BGL31_ORYSJ
Sequence: MTPARVVFICCVVLLAAAAAAASSSTAAGITRADFPPEFIFGAGSSAYQVEGAFAEDGRKPSIWDTFSHSGYSVDGATGDVTADQYHKYKEDVKLLQDMGVDAYRMSISWSRLIPDGRGAVNPKGLEYYNNLIDELLSHGIQPHVTIYHFDFPQALQDEYNGILSPRFVEDFTAYADVCFKNFGDRVKHWSTVNEPNIEPIGGYDQGILPPRRCSFPFGVLSCDNGNSTTEPYIVAHHLLLAHSSAVSLYREKYQATQGGQIGLTLLGWWYEPGTQDPEDVAAAARMNDFHIGWYMHPLVYGDYPPVMRKNVGSRLPSFTAEESKRVLESYDFVGFNHYVAIFVRADLSKLDQSLRDYMGDAAVKYDLPFLKSNNEFPLGLTSDFMTSTPWALKKMLNHLQEKYKNPIVMIHENGAAGQPDPSGGNTYDDDFRSQYLQDYIEATLQSIRNGSNVQGYFVWSFLDVFEYLFGYRLRFGLYGVDFASPERTRYQRHSARWYAGFLRGGELRPAAAALAGGGAYSQ
What are the official names of this protein?
Beta-glucosidase 31, Os9bglu31.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: QS2_TOBAC
Sequence: MDAANLVMKSSLFSKSPCPLFSSKLIPRAPPSVFTLPSTFRPLVKCIQASFPPNPDSKKPSNNSTFTCSAVTSFPSQQSQPHAPSDAKLQLLISEFQSLVEPMDRVKRLLHYSTLLPPMDASFKTPENRVPGCTTQVWLNVSFDEAENRMKFLADSDSEITKGFCACLVSLLDGATPDEVLALKTEDLNALNVAGLNGKGSASRANTWHNVLVSMQKRTRALVAEREGRPRGELFPSLVITADGIQPQGSYAEAQARFLFPDESRVQKLASLLKEKKIGVVAHFYMDPEVQGVLTAAQKLWPHIHISDSLVMADKAVSMAKAGCEYISVLGVDFMSENVRAILDLAGFPEVGVYRMSDERIGCSLADAAASPAYLDYLKTASTSSPSLHVVYINTSLETKAYSHELVPTITCTSSNVVQTILQAFAEVPDLEVLYGPDTYMGSNIAELFTQMSTMTDEEISAIHPLHNRISIKSLLPRLHYFQDGTCIVHHLFGHEVVEKINEMYGDAFLTAHFEVPGEMFSLAMEAKKRGMGVVGSTSNILDFIKERVEESLNRNVDEHLQFVLGTESGMITAIVAAVGKLLGSADSSSGGAKVSVEIVFPVSSESVTRTSTGSPLDQNKVNIIPGVASGEGCSLHGGCASCPYMKMNSLSSLLKVCQSLPHGKAELSAYEAGRFSLRTPKGKQIADVGCEPVLHMRHFQATKRLPEQLINQILQPRDNGRSSSA
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:23953973, PubMed:31276744).  Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity).
What are the official names of this protein?
Quinolinate synthase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: S35G1_HUMAN
Sequence: MRPQDSTGVAELQEPGLPLTDDAPPGATEEPAAAEAAGAPDRGRCWLCLSSPCCSRTEPEAKKKAPCPGLGLFYTLLSAFLFSVGSLFVKKVQDVHAVEISAFRCVFQMLVVIPCLIYRKTGFIGPKGQRIFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVFTSIFAWICLKEKYSPWDALFTVFTITGVILIVRPPFLFGSDTSGMEESYSGHLKGTFAAIGSAVFAASTLVILRKMGKSVDYFLSIWYYVVLGLVESVIILSVLGEWSLPYCGLDRLFLIFIGLFGLGGQIFITKALQIEKAGPVAIMKTMDVVFAFIFQIIFFNNVPTWWTVGGALCVVASNVGAAIRKWYQSSK
What is the function of this protein?
May play a role in intracellular calcium sensing and homeostasis.  May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell.
What are the official names of this protein?
Solute carrier family 35 member G1, Partner of STIM1, Transmembrane protein 20.
What is the protein family that this protein belongs to?
Belongs to the TMEM20 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane.
Protein: CRTO_STAAS
Sequence: MKTMKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
What is the function of this protein?
Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i. e.  the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin.  This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains (By similarity).
What are the official names of this protein?
Glycosyl-4,4'-diaponeurosporenoate acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase CrtO family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MRAY_PAEAT
Sequence: MIALLIGAGVALLVALIGTPLFIRFLVAKSYGQFIRDDGPTSHHTKRGTPTMGGTVVVAAVLISYFVTHLIMWMMNPDSAGPSASGLLLLFLMVGMGFVGFLDDFIKISNKRSLGLNARAKLILQAAVGIIFAVLVLQFPNEDGLRPASTQISLVRDIPWLDLAFGGTVVGAILFVLWSNLIITAATNGVNLTDGLDGLAAGASIMVFGAYTIMGIWQNNQACGSPREAGSGCYQVRDPMDLALLAAILSAALVGFLWWNTSPAKIFMGDTGSLAIGGAVAAFAILSRTELLLAFIGGLFVLITLSVIIQVGFFKLSGGKRVFKMAPLQHHFELKGWDEVTVVVRFWILAGLFVAAGLGIFYAEWVVLL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYSD_PSEFS
Sequence: MVDKLTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLARKAFFPGKLPFPVMHVDTRWKFQEMYTFRDKMVEELGLDLITHVNPDGVAQGINPFTHGSAKHTDIMKTEGLKQALDKHGFDAAFGGARRDEEKSRAKERVYSFRDSKHRWDPKNQRPELWNVYNGNVNKGESIRVFPLSNWTELDIWQYIYLEGIPIVPLYFAAERDVIEKNGTLIMIDDDRILEHLSDEDKARIVKKKVRFRTLGCYPLTGAVESEAETLTDIIQEMLLTRTSERQGRVIDHDGAGSMEDKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: LOLC_BUCAI
Sequence: MYKPISLFIALRYLWNTHLPNFKKIITILSIIGISITTASLIIITSIINGSEKNFEKNILSFIPHLIITNKNQCIKKDQFPENILKLNNIKNISDLISKEIIVQSKNDISMAEVIGIDHTNYYNIHNYNIKSVLKTLKPGYYNIIIGKQLARKLNVFIGDRLKLIFLSNTKNFFSGEIFKQRTFKIINFFSTKKEVDYYQILMNKEDSLNFLNYSKDYVTGWRVWLKNPLSLNVNEIKKITHPLFLLDWTTQKGELFKAMKIEKYIMFLFLFLVLLVSILNIVVILTICTVEKQNAVAILQTQGLLNCKIMLIFIIFGSSTAIIGNILGTLISLTLIIQNDFLKFFINIFIDETNIPIIVIPYQIFFINITITLFTILSTLYPSWKAIQLKPSRILSNE
What is the function of this protein?
Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane.  Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity).
What are the official names of this protein?
Lipoprotein-releasing system transmembrane protein LolC.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUBR_MEGGA
Sequence: MDIYVCTVCGYEYDPAKGDPDSGIKPGTKFEDLPDDWACPVCGASKDAFEKQ
What is the function of this protein?
Electron acceptor for cytoplasmic lactate dehydrogenase.
What are the official names of this protein?
Rubredoxin, Rd.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_NASOF
Sequence: MPIGVPKVPFRSPGEGDTSWVDIYNRLYRERLFFLGQEVDTEISNQLISLMIYLSIEKDTKDLYLFINSPGGWVISGMAVYDTMQFVRPDVQTICMGLAASIASFILVGGAITKRIAFPHARVMIHQPASSFYEAQTGEFILEAEELLKVRETITRVYVQRTGKPIWVVSEDMERDVFMSATEAQAHGIVDLVAVQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: COAD_OCEIH
Sequence: MGKLAICPGSFDPITNGHLDIIQRGANVFEEVIVTVFNNQSKSPLFSVTERIELLEDSIKHIPNVSVDSSSRLLMDYAREKKAHAVIRGLRAVSDFEYEMQITSMNRKLNEDIETLFMMTNNQYSFLSSSMVKEIAKYDGNISGLVPEPVEKALKAKFNYL
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_YERPB
Sequence: MYAVFQSGGKQHRVSEGQTIRLEKLDIATGETIEFDQVLMIANGEEINIGAPLVDGGKIKAEIIAHGRGEKIKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GSA_KINRD
Sequence: MTAPTPAPTTSSAPTSAALFERAAAVIPGGVNSPVRAFRAVGGTPRFTASARGPYLTDADGREYVDLLCSWGPMILGHAHPDVLAAVTAAAQDGFSYGTPTEREVLLAEEIVARVEPVEQLRMVSSGTEATMSAIRLARGFTGRPVIVKFAGHYHGHVDALLASAGSGLATFALPDTPGVTGTAAGDTIVIPYNDPEALAEVFRLHGDRIACVITEAAAGNMGVVAPQPGFTAELRRVTREHGALLVSDEVMTGFRVSAAGWYGHEGLGLEHAPDLLTFGKVMGGGFPAAAFGGRADVMAHLAPAGPVYQAGTLSGNPIATAAGLATLRACTPEVYAAVETAATAVREAASAALSAAGVPHLVNTAGSMFSVFFTGLDAVTDYEQARQQDLGAFRAFFHSMLDQGVHLPPSAFEAWFLSASHDEAAIGRVVEALPAAARAAAEGSGSL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BRUME
Sequence: MAKISKRINKIHEGVDRNKLYDLSAAIGLVKERAVAKFDETVEIAMNLGVDPRHADQMVRGVVNLPNGTGRTVRVAVFARGDKAEEAKKAGADIVGAEELFEIVNGGKIEFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTTDVAAAVAASKGGAVEFRVEKAGIIHAGIGKVSFDNAKLEENIKAFADAVIKAKPSAAKGEYVKRVSISSTMGVGVKVDPSTVKVVD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SIL1_YARLI
Sequence: MKFSKTLLLALVAGALAKGEDEICRVEKNSGKEICYPKVFVPTEEWQVVWPDQVIPAGLHVRMDYENGVKEAKINDPNEEVEGVAVAVGEEVPEGEVVIEDLTEENGDEGISANEKVQRAIEKAIKEKRIKEGHKPNPNIPESDHQTFSDAVAALRDYKVNGQAAMLPIALSQLEELSHEIDFGIALSDVDPLNALLQILEDAKVDVESKIMAARTIGASLRNNPHALDKVINSKVDLVKSLLDDLAQSSKEKADKLSSSLVYALSAVLKTPETVTRFVDLHGGDTLRQLYETGSDDVKGRVSTLIEDVLATPDLHNDFSSITGAVKKRSANWWEDELKEWSGVFQRSLPSKLSSKVKSKVYTSLAAIRRNFRESVDVSEEFLEWLDHPKKAAAEIGDDLVKLIKQDRGELWGNAKARKYDARDEL
What is the function of this protein?
Required for protein translocation and folding in the endoplasmic reticulum (ER).  Probably functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2.  It is not required for viability but is essential for optimal growth at elevated temperatures.
What are the official names of this protein?
Nucleotide exchange factor SIL1, Protein SLS1.
What is the protein family that this protein belongs to?
Belongs to the SIL1 family.
Protein: RS16_ANAMF
Sequence: MSVKIRLMRLGAKKKPFYRVVVSDSRVQRDGKFIEHVGFYDPMVPCGEPGFLKIDAERLSYWLGVGAQPTDRVSWFIKKGFVEVRPAGA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MEF2D_XENLA
Sequence: MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGDDSIDQSPLMEDKYRKSSEDLDILFKRYGSAVPAPNFAMPVTVPVTNQNALHFSNPGGSLITQSLMTSSLTDPRLLSPPQPSLQRNTVSPGLPQRPASAGAMLGGELNNSNGTCPSPVGNGYISARASPGLLPVSNGNSLGKVIQAKSPPSPNQNSQLGANSRKPDLRVITSQGGKGLMHHLTEEQLEMSVQRLGGVSQATHSLTTPVVSVATPSLLSHHGLPFSAMSTAYNTDYQLTSADLASLSTFSSPGSLSLGNVTAWQHQQQQQQQHNQPQQLIPVSLSNLVSSSHLPHTATLTVNTNPINISIKREPASPNRERSTGTPLSCFSHQSRHEATGRSPVDSLSSNASSFEGNDREDPRGDYTSSLGLLRPSGDTESESQSVKRMRLDAWVT
What is the function of this protein?
May regulate muscle-specific transcription in the embryo and may regulate transcription of a variety of cell types in the adult.  It binds to the sequence 5'-CTA[TA]4TAR-3'.
What are the official names of this protein?
Myocyte-specific enhancer factor 2D homolog, Serum response factor-like protein 1, SL-1.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APOA1_CAVAP
Sequence: MKAVLLVVAALFLAGSQARHFWQQDDPKTSWDVVKEFANKYVDAVKESGKGYVEQLDASSLGQQLNLRLSDNWDTLSTILTKLQADFGLATQEFWDTLEKETEWLKQIVSEDLQDVKHKVQPYLENFQKKVQEEVERYREKVRPLGIELRDGARQKLQELQEKLTPLGEDLRDRTREHVDVLRTQLAPFSEEMRQRLAKRLEELKDSATLADYHAKASEHLKMLGEKAKPALEDLRQGLLPVLENLKASILSSIDQASKQLAAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL13_MYCMS
Sequence: MKQTTMISAKDTNKKWYIVDAENKTVGRLATQVALVLRGKHKVDFTPHINNGDHVIIINAEKAIFSGKKESNKFYYHHSMHPGGLKKRSVEVQRELDATKILERAIRLMLPKNVQGSNQYRALHVFKGSNHPFAAQKPEVLEISTKKGDVK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ALX1_MOUSE
Sequence: MEFLSEKFALKSPPSKNSDFYMGTGGALEHVMETLDNESFYGKATAGKCVQAFGPLPRAEHHVRLDRTSPCQDSSVNYGITKVEGQPLHTELNRAMDNCNNLRMSPVKGMPEKSELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLPRDASSCMTPYSHSPRTDSSYTGFSNHQNQFSHVPLNNFFTDSLLTGATNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM
What is the function of this protein?
Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes (PubMed:12929931).  Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures.  Early on in development, it plays a role in forebrain mesenchyme survival (PubMed:8673125).  May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1 (By similarity).
What are the official names of this protein?
ALX homeobox protein 1, Cartilage homeoprotein 1, CART-1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL15_STRPN
Sequence: MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIVKAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: KDM7A_MOUSE
Sequence: MAGAAAAVAAGAAAGAAAAAGSVSAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDVCKDWFHGSCVGVEEHHAVDIDLYHCPDCAALHGSSLMKKRRNWHRHDYTEVDDGSKPVQAGTRAFVKELRSRVFPSADEIIVKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPAFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPDRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKSLLETLKELKEDGFQPQSYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIEEENGKPVKSQGIPSVCPVSRPSNEASPPYHSRRKMRKLRDHNVRTPSNLDILELHTREVLKRLEMCPWEEDLLSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQLFADRSLYTADSENEEDKKPTQNANMKTEQSSGREEAESQGSPKPLNRIFTSVRSELRSRPSEYSDGSDSEDSGPDCTALKINFATEDSESSGDEKKHEITSHFKEESDIVRNLLQKSQKPSRQEIPVKRECPTSTSTEEEAIQGMLSMAGLHYSSCLQRQIQSTDCSGEKNSLQDPSSCHGSNPEFRQLYRCNKPVEFGYHAKTEDQDLMTSSWNKQFDRTSRFNAQDLSRSQKHIKKESSSEINQKAQSRHCVDSNSSSIQNGKYTLNPSLVSCQISNGSLSPERPIGETSFSMPLHPTKRPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV
What is the function of this protein?
Histone demethylase required for brain development.  Specifically demethylates dimethylated 'Lys-9', 'Lys-27' and 'Lys-36' (H3K9me2, H3K27me2, H3K36me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code.  Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2.  Demethylates H3K9me2 in absence of H3K4me3.  Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.
What are the official names of this protein?
Lysine-specific demethylase 7A, JmjC domain-containing histone demethylation protein 1D, Lysine-specific demethylase 7, [histone H3]-dimethyl-L-lysine9 demethylase 7A.
What is the protein family that this protein belongs to?
Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CINAL_SHESM
Sequence: MMKLEMVCTGEEVLSGQIVDTNAAWFASTMMEHGIEIQRRVTVGDRLEDLIAVFQERSLHADVILVNGGLGPTSDDMSAEAMAKAKGESLVENREWRQHLEDWFTRNNREMPVSNLKQAMLPESAVMVDNPVGTACGFRVKLNRAWLFFTPGVPFELKHMVKEQFIPFIREEFGLDAKVALKKLLTIGHGESSLADKIEPLELPEGITIGYRSSMPHIEIKIFARGEKAIALLPRVTGHIKMVLGTAVVAEDKATLAEEIHAKLLNSGLTLSVAESCTGGMITSQLVDFPGSSSYLQHGLVTYSNESKVRVLGVNPATLDDHGAVSIPTVEEMAKGARAILDSDFALATSGIAGPDGGTEEKPVGTVAIALATRSGVYSQMIKLPRRSRDLVRSLSAAVAYDMLRRELLTEAVIVDYQSIGRFSK
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: ENO_LACE2
Sequence: MAAYLEIEKVIGREILDSRGNPTVEAEVYLADGTVGRGAAPSGASTGEFEALELRDKDKSRYLGKGVTKAVENINTVINDCLFGIDASDIYAVDAAMIKADGTKDKSNLGANAILAVSIAAARAASVSLDIPLYRFLGGVSGNRLPVPMMNIINGGCHALSSGLDVQEFMIMPVGAPSFKECLRWCAEVFHALAAILKERGLATSVGDEGGFAPALKSDEEAIETILQAVEKAGYKPGRDFRIAMDAASSEWKSEKGKGYYKLPKAGTEYTAEELIEHWAKLCEKYPIISIEDGLDEEDWEGWKKLTDRLGDKVQLVGDDLFVTNTERLSKGIELGAGNAILIKLNQIGSVSETLEAIKMAHKAGYTAISSHRSGETADTTIADLAVALNTCQIKTGAPSRSERVAKYNQLLRIEEQLGASAVYPGIRAFNVNND
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SNAPN_YEAS2
Sequence: MAGDSISADGTGVHPVELSVYSVLSTDLDGLYQSINELRESQALLILMLRKVRDKLRREGQVLYDPEPFKPTMDKLADLSARVHILSQRYEELQGNVRALNN
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit SNN1, BLOC-1 subunit SNN1, SNAPIN-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SNAPIN family.
What are the subcellular locations of this protein?
Endosome.
Protein: BPT_RHOPS
Sequence: MTQHSRDTPQFYLTAPSPCPYLPGRHERKVFTHLVGNKAGELNDLLTHGGFRRSQSIAYRPACDQCRSCVSVRVIANEFRASRNQRKILARNADIVGEQRNPVPTSEQYSVFRAYLDQRHRHGGMADMTVLDYAMMVEDSHVETRIIEYRKRTLDTGITGRGGDLVAAALTDVLNDGLSMVYSFYEPGEQNRSLGTFMILDHIARARRLGLPYVYLGYWIEGSKKMDYKGRYLPQQRLAPSGWIRVDASGEYPEPQD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_WOLTR
Sequence: MSKKDYYKLLGVDRNASTDEIKKAYKKLALKYHPDRNPGNKEAEEKFKEITAAYEVLSDSEKRAGYDRYGHEGASGGFDFSQGFGSAGDFSDIFNDFFGGEFGSSSRSKAKRSTTGVPGADLRYDLEITLEDAFKGIQAPIHYVTNVKCDMCQGRGSEGATKPVQCHTCQGSGRIRTQQGFFTIERTCTTCYGEGEIIQNKCKKCNGSGRRRDEVNISVSIPKGIEEGAKVRVSGKGEAGAKGGKSGDLYVYVKITPHKIFTRNKADLHCKVPIRMTLAVLGGEIDVQSIDGAKIKVKVPEGTQTSTKLRCKEKGMPYMNSYARGDLYVQIIVETLNPNNLTKKQIELLKALEEEENASIQQQSEGFFSKVKKK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.