PharMolix/UniProtQA huggingface dataset:
Protein: NACA_PICGU
Sequence: MSIEEIPEEIPQGADVTILSKNEKKARELIKKLHLKPVPGITRVTFKQKGNLIYAIEQPDVFKSAAGTYVVFGEAKVDDMNKRIAEAQAQQEQQEALTKAAADAETADKSPESITNDLQNASLEDKTVEEDEGEVDETGLDSKDIEIIVEQTQVSRAKAVKALRAHKGDMVNAIMELS
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD2 may also be involved in transcription regulation (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: ACTP_SALPK
Sequence: MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTEAMAVHPKGTAIMSPGGLVQDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPAYKDAAGALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATEREELKVSKITVLVLGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TSN6_HUMAN
Sequence: MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV
What are the official names of this protein?
Tetraspanin-6, Tspan-6, A15 homolog, Putative NF-kappa-B-activating protein 321, T245 protein, Tetraspanin TM4-D, Transmembrane 4 superfamily member 6.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
Protein: YQHA_SALEP
Sequence: MERFLENVMYASRWLLAPVYFGLSLALIALALKFFQEILHVLPNVFALAEADLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISAGKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YQ65_SCHPO
Sequence: MTGTAKVSIPKAQPHKVPCVYLAGDLVFRPNAIELFDELKEICKDAGVQGVAPFDGQEGVEEMAPGAETSLKIAELDRKLMDRCDGGIFCLDPFRRAPDMDPGTAVELGYMAAQGKPLAGFTTDGRMYPEKVRSYRKQAWGDALKPRFTKGGSGSMEDADGLIVHSEGFLQNVMTEGFIRMSGGFVAVDFSIQEAFRTAIKDLAARLNSQH
What are the official names of this protein?
Uncharacterized protein C191.05c.
What is the protein family that this protein belongs to?
Belongs to the nucleoside deoxyribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OPGC_ECO55
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FCF1_SCHPO
Sequence: MGKAKTTRKFAQVKRVINLKDQRLQKKDQKKEKEKTTKNGELVREIPQMASNLFFQFNESLGPPYHVIIDTNFINFCLQQKIDLFEGLMTCLYAKTIPCISDCVMAELEKLGIRYRIALRIAKDERFERLPCTHKGTYADDCIVQRVMQHKCYLVATNDKNLKQRIRKIPGIPILSVANHKIRVERLVDVVD
What is the function of this protein?
Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly.  Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites (By similarity).
What are the official names of this protein?
rRNA-processing protein fcf1.
What is the protein family that this protein belongs to?
Belongs to the UTP23/FCF1 family. FCF1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYFA_HALS3
Sequence: MQLPTQQVAVLDAASTDDPQRIEALAADTDYPPETIAGAALALEAEGLVAVTETTTTTVSLTDEGHAYATDGLPEVRLYRAALDAGADDAPVEMGSVIGAAGLDGPQVDIALSNYARKGYGTIDSGALAADPDADPENDPEADALATLTDGDSVDDDAVVDQLASRDLVTVSERTVRSVTLTEAGVTELMAGVEATDEVGELTPELLASGEWADVEFADYNVAADAADHTPGKTHVLRQAAERVTDVLVGMGFQEMAGPHVDADFYINDCLFMPQDHPARNHWDRFALSNPARIDELPDALVERVERAHREGAGDDGDGYHSPWDEDFARALALRGHTTSLTARHLAGLADADVEAPARYFSVEKAYRNDTLDATHLLEFFQIEGWVLADDLSVRDLMGTFREFYSQFGIHDLQFKPTYNPYTEPSFELFGRHPETGELIEIGNSGIFRPEMLDPLDVDGDVMAWGLALERLLMLMTGFEDIRDVHGTLCDVGFLRNAEVVY
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEMO1_RAT
Sequence: MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPHAGYTYCGSCAAHAYKQVDPSITRRIFILGPSHHVPLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFERMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYHNTICGRHPIGVLLNAITELQKSGMNMSFSFLNYAQSSQCRSWQDSSVSYAAGALTVH
What is the function of this protein?
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton.  Mediator of ERBB2 signaling.  The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex.  It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.  In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization (By similarity).
What are the official names of this protein?
Protein MEMO1, Mediator of ErbB2-driven cell motility 1, Memo-1.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: RR4_TOBAC
Sequence: MSRYRGPRFKKIRRLGALPGLTNKKPRNGSDLRNQSRSGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIARKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPAARQLVNHRHILVNGRIVDIPSYRCKPRDIITAKDEQKSRALIQISLDSSPHEELPNHLTLHPFQYKGLVNQIIDSKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NQOR_RHOPA
Sequence: MAKVLVLYYSAYGHIEAMANAVAEGAREAGATVDIKRVPELVPPDVAKASHYKLDQAAPVATIEDLANYDAIVIGTGTRFGRMASQMSNFLDQAGGLWARGALNGKVGGAFTSTATQHGGQETTLFSIITNLLHFGMVVVGLNYGFGDQMRLDQVTGGAPYGATTITGGDGSRQPSETELAGARYQGKTIAETAIKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: FDHB_METJA
Sequence: MKYVLIQATDNGILRRAECGGAVTALFKYLLDKKLVDGVLALKRGEDVYDGIPTFITNSNELVETAGSLHCAPTNFGKLIAKYLADKKIAVPAKPCDAMAIRELAKLNQINLDNVYMIGLNCGGTISPITAMKMIELFYEVNPLDVVKEEIDKGKFIIELKNGEHKAVKIEELEEKGFGRRKNCQRCEIMIPRMADLACGNWGAEKGWTFVEICSERGRKLVEDAEKDGYIKIKQPSEKAIQVREKIESIMIKLAKKFQKKHLEEEYPSLEKWKKYWNRCIKCYGCRDNCPLCFCVECSLEKDYIEEKGKIPPNPLIFQGIRLSHISQSCINCGQCEDACPMDIPLAYIFHRMQLKIRDTLGYIPGVDNSLPPLFNIER
What is the function of this protein?
Catalyzes the oxidation of formate.
What are the official names of this protein?
Formate dehydrogenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the FrhB family.
Protein: RF3_ECOSM
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIF2_ORYSI
Sequence: MGPQQDRSAAKPYANGSTAAAAAAGRKENNKVVRYRECQRNHAASIGGHAVDGCREFMASGADGTAAALLCAACGCHQSFHRREVEAAAAECDCSSDTSSGTGRR
What is the function of this protein?
Inhibits zinc finger homeodomain (ZHD) transcription factors, by interacting with them to prevent both their nuclear localization and their DNA-binding properties.
What are the official names of this protein?
Mini zinc finger protein 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_MYCPA
Sequence: MSRIGKQPVPVPAGVDVTIDGQKVSVKGPKGTLDLTVAEPITVSRNDDGAIVVTRPNDERRNRSLHGLSRTLVSNLVTGVTQGYTTKMEIFGVGYRVQLKGSNLEFALGYSHPVVIEAPEGITFAVQSPTKFSISGIDKQKVGQISANIRRLRRPDPYKGKGVRYEGEQIRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: COMT_PIG
Sequence: KERAMHVGRKKGQIVDTVVQEQRPSVLLELGAYCGYSAVRMARLLLPSARLLTIELNPDNAAIAQQVVDFAGLQDRVTVVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGCGRFECTHFSSYLEYSQMVDGLEKAVYKGPGSPAQP
What is the function of this protein?
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.  Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
What are the official names of this protein?
Catechol O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Single-pass type II membrane protein; Extracellular side.
Protein: Y183_TREPA
Sequence: MKKGVRSSRLLILFVLFAHAVHAAPRVGVYRLEVSGVPAHTETTINDALFSFIRELRGYHVVDCREQAVPHRFPEKGNLDYIFCGAMDLTPEGIRLAVALKGKDHNATRLLSKTYETAARILLDSRHLVRDVFDRSVPLTGNQTETSSMRHTRAGEESVSSLDALAGSWHSTEEGERIVIVSEGRGIAVLRSGLSVPLKLKISDGVLVVSQKGAVNARQFSHFPPEIAQKLAQEARPLQWRFPKISGNNRLSGVRTAPVVRGAGHTASVEYEEVPEEWVRN
What are the official names of this protein?
Uncharacterized protein TP_0183.
Protein: BIOF_YERPG
Sequence: MSWQDKIAQGLQRRRDAAAYRTRQVNEGANGRWLQSGERQYLNFSSNDYLGLSQNDEVIAAWQQGARRYGVGSGGSGHVTGYSQPHARLEQQLADWLGYPRALLFISGYAANQAVLTALTDADDRILADKLSHASLLEAAAHSPAQLRRFQHNQPEALQNLLIKPCQGQTLVVTEGVFSMDGDSAPLAALQQQTSAAGGWLLVDDAHGIGVHGEGGRGSCWLQGVQPELLVVTFGKAFGLSGAAVLCQEPVAEYLLQYARHLIYSTAMPPAQACALQAALRQVQQGDALRQQLQQRIRQFRTAAAHLPLQLGASKTAIQPLLVGDNQQSLIWAEQLRAAGLWVTAIRPPTVPPGSARLRITLSAAHQPEDIDRLLEVLYGLCH
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: PHNW_PSEF5
Sequence: MSIAEPILLTPGPLTTSARTRQAMLVDWGSWDDRFNQLTASLCQQLLAIIQGADSHHCVPLQGSGTFAVEAAIGTLVPRDGKVLVLINGAYGKRLAKICEVLGRDFSTFETAEDQPTTAADVERLLQADSSISHVALIHCETSTGILNPLPEIAQVVASHGKRLIIDAMSSFGALPIDAREIPFDALIAASGKCLEGVPGMGFVFAAKASLAQAGGNAHSLAMDLHDQHSYMAKTGQWRFTPPTHVVAALHEALLQYAEEGGLPARHARYADNCQTLLDGMGELGLRSFLPEAIQAPIIVTFHAPKDPRYQFKDFYERVKAKGFILYPGKLTQVETFRVGCIGHVDRRGMQAAVAAIAEVLQEMEVLDI
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: C1QT7_HUMAN
Sequence: MFVLLYVTSFAICASGQPRGNQLKGENYSPRYICSIPGLPGPPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQGETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGITTSYPEERLPIIFNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLANKHLAIGLVHNGQYRIKTFDANTGNHDVASGSTVIYLQPEDEVWLEIFFTDQNGLFSDPGWADSLFSGFLLYVDTDYLDSISEDDEL
What are the official names of this protein?
Complement C1q tumor necrosis factor-related protein 7.
What are the subcellular locations of this protein?
Secreted.
Protein: GE_EHV1B
Sequence: MELLAASRACIFFGLVTVLDAWGVQQVELSEGAWAMIDGRDVLTPTNTTTRVTKAWTFLETPPGCAGDISVKKVCVSHSLCEDNIIIGKHCNLLTGEHGIALAEFNVVNGSLRRTDDVYFVNGTVFPILAETRSVLQIHRATPSIAGVYTLHVSIDGMMKHSVVLLTVKKPPKQPQPRLRVKTPPPVTVPQVPVKTHTDFVVHGYHSRVYADGESFELSVNLESHIVEPSFSAEIQWYYMNTSSSSCDLFRVFETCIFHPTAMACLHPEQHTCSFTSPIRATKILHRVYGNCSDHGNSWPSRCHSTLLGNRLYFIQPAQNRVDLLFKDTPASATGLYVFVLLYNGHPEAWTYTLLSTANHFMNVLTDVTRPRLGEHFYTDLGHKIITPHPSVATTEELGAWTRHYLAFLLVIICTCAALLVALVVWGCILYIRSNRKPYEVLNPFETVYTSVPSNDPSDEVLVFERLASDSDDSFDSDSDEELEYPPPPKPAPQLPPYQFVDGGDAPSGRSGFKVWFRDTPEASPVPLHKPTLQGPDYSRVASKLKSILK
What is the function of this protein?
In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions.  Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions.  Implicated in basolateral spread in polarized cells.  In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.  Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips (By similarity).
What are the official names of this protein?
Envelope glycoprotein E, gE.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein E family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus membrane; Single-pass membrane protein. Host endosome membrane; Single-pass membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN), maybe through an interaction with PACS-1 sorting protein. The heterodimer gE/gI then redistributes to cell junctions to promote cell-cell spread later in the infection (By similarity).
Protein: TCAB4_TULGE
Sequence: MSVALFCGPPPAVSFGCKDGRGRKGMVRSKDIVRQTVKPPAHACRLIGWNKYPGSVVPTNSSLSPSPTALDDEIELDPSPFLIIYKDGRIERLKGTTVIPACPEVATKDVIIDPATGVSVRLYLPNVVDLPSKKLPVLVYFHGGGFVIENTGSPNYHNYLTLLAAKSGLLIVSVNYRLAPEHPIPASFDDCMAGFNWVVSHSAGPAPEPWLARHGDLTQILISGDSAGGTVTHYVLLRADAGVIEGAALVHPYFLGSKRLENQTEEDFEFHEKLWRLSTPDTEGLDDPLINPLAPGAPSLAGLKCKRAVVFVAELDFLVERGRMYYDALVKSGWGGEAELVHQKGVGHVFHLSDYSGDVSVDMMAKMVAFLRGE
What is the function of this protein?
Lactone-forming carboxylesterases, specifically catalyzing intramolecular transesterification, but not hydrolysis.  Involved in the biosynthesis of tulipalins, defensive chemicals that show antimicrobial activities against a broad range of strains of bacteria and fungi.  Substrates are 6-tuliposide A > 6-tuliposide B (By similarity).
What are the official names of this protein?
Probable tuliposide A-converting enzyme b6, amyloplastic, TgTCEA-b6.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Plastid, amyloplast.
Protein: TSAD_LIMRD
Sequence: MTERTLTLAFESSCDETSVAVIENGTKILSNIVATQIDSHQRFGGVVPEVASRHHIEQITKCTNEALEQADVDYNDLDAVAVTYGPGLVGSLLIGVTAAKAIAWAHNLPLVPVNHMAGHIYAARYVGEFQYPQMALLVSGGHTELVYMPSEHEYQIIGETRDDAAGEAYDKIGRVLGVNYPAGKTIDEWAAKGKDTFNFPRAMEKEDNYDFSFSGLKSAFINTVHNADQRGEKLDKYDLAASFQQSVIDVLAEKTMRALDDYPVKQLILAGGVAANHGLRARLDHDMKEFHPDVPMLQAPLKLCGDNAAMIGAAGYVNYKHGDRAGLDLNAVPGLMFDRIQSK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_EMEND
Sequence: MYQFNFILSPLDQFEIRDLFSLNANVLGNIHLSITNIGLYLSIGLLLTLGYHLLAANNKIIPNNWSISQEAIYATVHSIVINQLNPTKGQLYFPFIYALFIFILVNNLIGMVPYSFASTSHFILTFSMSFTIVLGATFLGLQRHGLKFFSLFVPSGCPLGLLPLLVLIEFISYLSRNVSLGLRLAANILSGHMLLSILSGFTYNIMTSGILFFFLGLIPLAFIIAFSGLELAIAFIQAQVFVVLTCSYIKDGLDLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y708_ACTPJ
Sequence: MADVKKQSFQDMLDYVHLYRLKNKLHRETADNDRKIRDNQKRVLLLDNLNQYINDSMTVEDIRAIIANMRDDYENRVDDYMIRNAELSKQRREIRQKMAAHKTSASEKSEK
What are the official names of this protein?
UPF0265 protein APJL_0708.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: TCP4_MOUSE
Sequence: MPKSKELVSSSSSGSDSDSEVEKKLKRKKQAVPEKPVKKQKPGETSRALASSKQSSSSRDDNMFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL
What is the function of this protein?
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery.  May be involved in stabilizing the multiprotein transcription complex.  Binds single-stranded DNA.  Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
What are the official names of this protein?
Activated RNA polymerase II transcriptional coactivator p15, Positive cofactor 4, PC4, SUB1 homolog, Single-stranded DNA-binding protein p9, p14.
What is the protein family that this protein belongs to?
Belongs to the transcriptional coactivator PC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL31_HELVI
Sequence: MAKPKGERKGKSAINEVVTREYTVNLHKRLHGVGFKKRAPRAIKEIRKFAEKQMGTPDVRVDTRLNKFLWSKGVRNVPFRVRVRLSRRRNDDEDSAHKLFTLVTYVPVASIKGLQTENVDASQE
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: HSLO_DEIRA
Sequence: MLRGTAAGGTLRLVGIEASKVVEEARRRHNLSKTATAALGRTMAASALLAVVLGKRTDSRVTVRVDGGGPVGWIVAEGSTDGRLRGYVRQPEADLPPRESDGKLDVRGIVGTDGELAVTRLLDNGEPYTGSVRLQSGEIAEDVSRYLGASEQIPNAVLLGVYEEGGRVANAGGLLIQAMPGVTDETLAKLEANIAAMGMLTDQLRNGGLLGAMQQAAAGLDLQLATDAQPAHFSCRCSREKAIDSLKFFGAEERQEMIDEGGQEVLCHWCSEKYHLTPEEIAALDEGEARAEA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_BURCH
Sequence: MLFPTEFDVIVVGGGHAGTEAALASARMGAKTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAAATDESGIQFRILNSSKGPAVRATRAQADRILYKAAIRHRLENQPNLWLFQQAVDDLMVEGDRVVGAVTQIGIRFRARAVVLTAGTFLDGKIHVGLNNYTGGRAGDPAAVSLSSRLKELKLPQGRLKTGTPPRIDGRTIDFSKLDEQPGDLDPIPVFSFLGRADQHPQQLPCWVTHTNERTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKESHQIFLEPEGLTTHEFYPNGISTSLPFDVQLELVHSMRGLENAHILRPGYAIEYDYFDPRALKASLETKAINGLFFAGQINGTTGYEEAAAQGLLAGLNAGRYVQEKDAWCPRRDQAYLGVLVDDLVTRGVAEPYRMFTSRAEYRLSLREDNADMRLTEIGRELGLVDDARWDAFSRKRDAVSRETERLKSTWVTPKTLPVEEATALLGKAIDHEYSLAELLRRPGVSYDGVCGLKGGECGPAEPLADDPVLLEQIKEQVEIGIKYQGYIERQASEIERNDANENTRLPDGIDYREVRGLSFEVSQKLNEFRPETIGQASRISGVTPAAISLLMVHLKRRGLGRRNGTAAEAAEQGDGAVPTQQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.