PharMolix/UniProtQA huggingface dataset:
Protein: RL6_CLOK5
Sequence: MSRIGKLPIAIPAGVTFTVTPDNVVTVKGSKGQLVKAMAKDINIAVEDNSVVVTRNDDEKKSRSLHGLTRALINNMVVGVTEGYSKTLELIGVGYRAQLQGKKLVMNLGFSHPVEIEAVEGVTFETPAATKVVIKGIDKELVGNVAADIRSWRKPEPYKGKGIKYDNEVIRRKEGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YQGE_ECOSM
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDILVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MTNB_YERPP
Sequence: MTENRQLGALLAACHWIGEKGWCPATGGNMSLRLDLAHCLITESGKDKGSLAAEDFLLVETANNHVPSGRTPSAETGLHTLLYRLYPEIQAVLHTHSVNATVLSRVERSNALVLQGYEMQKSLSGQRSHLDAVVIPIFDNDQDIPALAQRVAAYADNRPLQYGFLVRGHGLYCWGNSVVEARRHLEGLEFLFQCELQRRLFDVNSNVDVKPNVDVNPNVEAK
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: MURG_PROMM
Sequence: MPRLLIAASGTGGHLFPALAVAEALPGSWSVCWLGVPDRLETQLVPERYELTTVRAGGLQGRGLRKLVQLLQLLAATGRVRKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESNAIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPVRSAFLSPQPLPRWVPCGDGPLLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDSDVGELDHPNLVEQPFSHEMPGLLQHADLAISRAGAGSLSELAVCGTPAILVPFPQAADQHQEANAACAAALGAAVIVHQHAAEHRALGHALEQLMGPRLRGNAAASNPLIPMKQGMRKLAVREADQLLVTLLKQLIGAGL
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DEOB_STAAT
Sequence: MTRPFNRVHLIVMDSVGIGEAPDAADFKDEGSHTLRHTLEGFDQTLPNLEKLGLGNIDKLPVVNAVEQPEAYYTKLSEASVGKDTMTGHWEIMGLNIMQPFKVYPNGFPEELIQQIEEMTGRKVVANKPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQIAAHEDIIPLEELYDICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALKPFGKTVLDHLKDGGYDVIAIGKINDIYDGEGVTEAVRTKSNMDGMDQLMKIVKKDFTGISFLNLVDFDALYGHRRDKPGYAQAIKDFDDRLPELFSNLKEDDLVIITADHGNDPTAPGTDHTREYIPVIMYSPKFKGGHALESDTTFSSIGATIADNFNVTLPEFGKSYLKELK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_CLOAB
Sequence: MRAVVQKVKKSSVKVDGKVVGQIGKGINALIGITEGDTLEDIEYLKNKILNLRIFEDEEGKLNKSLKDVNGELLVISQFTLYGDCRRGRRPSFIEALSGDKSEKIYNDFVDLCRKEVPNVQTGVFGAHMDVDIQNDGPVTLLIDSKKVF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM18_ASHGO
Sequence: MLNKRISNLATILRFIALPRARNIIAPQEYIANSVPVAITRRAARNTFVFSVALTPFVLYSAFHNDSAESDFPELVEVYPGVRPFPAVLGPPELPLQTNYKLLGHGVRAVTFLSFKVYALGIYAAVDDLPLIPRTLSAEYLSTLDTEKVDAPAKEQLYKAMQDHEKSRAVVNDLLGKGLRLVAKITPIRNTDFTHLKDGLVKSILNHPAARHEGETLANGLEELRAAFTRRGSVPKDDDLVLELQATGALQLYHRDAKTGQTTTLGKVTEPLIGRYLFSQYLSGKAPLSKDTKDSVTRKIISMV
What are the official names of this protein?
Altered inheritance of mitochondria protein 18, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM18/AIM46 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MTNB_PSEA8
Sequence: MNDNREQLTQQIIDAGRFLYGRGWSPATSSNYSARLDEQRALLTVSGKHKGQLGFDDVLATDLAGNSLEPGKKPSAETLLHTQLYAWNPAIGAVLHTHSVNATVLSRLVRGDRLVLQDYELQKAFAGVTTHEGQVEVPIFDNDQDIARLASRVQPWLEAYPHCPGYLIRGHGLYTWGARMSDALRQVEAFEFLFECELKVLSLSR
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: S12A3_HUMAN
Sequence: MAELPTTETPGDATLCSGRFTISTLLSSDEPSPPAAYDSSHPSHLTHSSTFCMRTFGYNTIDVVPTYEHYANSTQPGEPRKVRPTLADLHSFLKQEGRHLHALAFDSRPSHEMTDGLVEGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPIVDPINDIRIIAVVSVTVLLAISLAGMEWESKAQVLFFLVIMVSFANYLVGTLIPPSEDKASKGFFSYRADIFVQNLVPDWRGPDGTFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSCVVRDASGVLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARVDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVFVGGQINRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRAEHTKRFEDMIAPFRLNDGFKDEATVNEMRRDCPWKISDEEITKNRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLETLSQDLRPPVILIRGNQENVLTFYCQ
What is the function of this protein?
Electroneutral sodium and chloride ion cotransporter.  In kidney distal convoluted tubules, key mediator of sodium and chloride reabsorption (PubMed:21613606, PubMed:22009145).  Receptor for the pro-inflammatory cytokine IL18.  Contributes to IL18-induced cytokine production, including IFNG, IL6, IL18 and CCL2.  May act either independently of IL18R1, or in a complex with IL18R1 (By similarity).
What are the official names of this protein?
Solute carrier family 12 member 3, Na-Cl cotransporter, NCC, Na-Cl symporter, Thiazide-sensitive sodium-chloride cotransporter.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Protein: Y1729_STAA1
Sequence: MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
What are the official names of this protein?
UPF0354 protein SAHV_1729.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: NO552_SOYBN
Sequence: MASCLPNASPFLVMLAMCLLISTSEAEKYVVGGSEKSWKFPLSKPDSLSHWANSHRFKIGDTLIFKYEKRTESVHEGNETDYEGCNTVGKYHIVFNGGNTKVMLTKPGFRHFISGNQSHCQMGLKLAVLVISSNKTKKNLLSPSPSPSPPPSSLLSPSPSPLPNNQGVTSSSGAGFIGVMMWLMLLL
What is the function of this protein?
May act as a carbohydrate transporter.
What are the official names of this protein?
Early nodulin-55-2, N-55-2, Nodulin-315.
What is the protein family that this protein belongs to?
Belongs to the early nodulin-like (ENODL) family.
What are the subcellular locations of this protein?
Symbiosome, peribacteroid membrane.
Protein: MNME_STAA8
Sequence: MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSSR_STAA9
Sequence: MVQCLVVDDDPRILNYIASHLQTEHIDAYTQPSGEAALKLLEKQRVDIAVVDIMMDGMDGFQLCNTLKNDYDIPVIMLTARDALSDKERAFISGTDDYVTKPFEVKELIFRIRAVLRRYNINSNSEMTIGNLTLNQSYLELQVSNKTMTLPNKEFQLLFMLAARPKQIFTREQIIEKIWGYDYEGDERTVDVHIKRLRQRLKKLNATLTIETVRGQGYKVENHV
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme response regulator HssR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC2_SACS2
Sequence: MGIIDEAKRGQITDEMRAISKLEGIPVEKVRNRISEGKIMLIRNAKYPSRKLVPIGKGLTTKVNVNIGTSSEVVDLDMELQKVKVANKWGDTLMDLSTGGDLDAIRRDIIKASDLPVGTVPVYQIFIESFKKKSGGAYFTEDELLNTVEKHLKDGVAFMTIHAGITKDLAIRALKSDRIIPIVSRGGDMIAGWMIHNNSENPYRKNWDYVLEMFKEYDAVISLGDALRPGATGDAHDEFQIGELLETARLVKSALQKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGAPYDHIASAIGAAISSASGVDLLCYLTPAEHLGLPTVKQVEEGAIAYRIAAHAGDVVKLGRKARKWDDEVSYYRGKLDWENMISKLIDPQRAYQVYTQFGTPKVKACTMCGGYCPMMWAMDQVRKIGSSSSL
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase 2, Hydroxymethylpyrimidine phosphate synthase 2, HMP-P synthase 2, HMP-phosphate synthase 2, HMPP synthase 2, Thiamine biosynthesis protein ThiC 2.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y734_STAAS
Sequence: MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGRLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
What are the official names of this protein?
Epimerase family protein SAS0734.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
Protein: KORC_METTH
Sequence: MIEVRKEIRIAGFGGQGVILAGIVLGKAASLYDGLYAVQTQSYGPEARGGASRAEVVISDHEIDYPKVQSPDILVAMSHQALLTYMDDLKRGGALIVDPDMVVEAEIEDFIRAREVKYFRAPATRTAEERVGITIVANMVMIGALTEATGIVSVRAAEEAIKDSVPPGTEEKNLMAFQAGRELIMEGSR
What are the official names of this protein?
2-oxoglutarate synthase subunit KorC, 2-ketoglutarate oxidoreductase gamma chain, KOR, 2-oxoglutarate-ferredoxin oxidoreductase subunit gamma.
Protein: BOML1_BOMVA
Sequence: QRLGHQWAVGHLM
What is the function of this protein?
Possesses insulin-releasing activity.
What are the official names of this protein?
Bombesin-like peptide 1.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FARA_NEIGO
Sequence: MKSGNSEPNLMETHTDETKLQNTQVKRKRRLTALTLLFALSAAAAGSAFFLWWQHEEETEDAYVAGRVVQVTPQKGGTVRKVLHDDTDAVKKGDVLAVLDDDNDVLAYERAKNELVQAVRQNRRQNAATSQAGAQVALRRADLARAQDDLRRRSALAESGAVSAEELAHARTAVSQAQAAVKAALAEESSARAALGGDVSLREQPEVQTAIGRLKDAWLNLRRTQVRAPADGQVAKRSVQVGQQVAAGAPLMAVVPLSDVWVDANFKETQLRHMKIGQPAELVSDLYGKQIVYRGRVAGFSAGTGSAFSLIPAQNATGNWIKVVQRVPVRIVLNREDVDRHPLRIGLSMTVKVDTSAAGAPVSKTPGAALPEMESTDWSEVDRTVDEILGQSAP
What is the function of this protein?
Mediates resistance to long-chained antibacterial fatty acids (FAs) (PubMed:10447892).  Function is dependent on the MtrE outer membrane protein (PubMed:10447892).
What are the official names of this protein?
Fatty acid resistance protein FarA, Efflux pump protein FarA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UVRC_DESAH
Sequence: MTPSVLERYQSAPQNPGVYLMKDKRGTIIYVGKALNLKKRLASYFARETGHDMKTGVLLKKVVDFDLIVTATEHEALILESTLIKKHSPRYNVILKDGKSYPCLRIDTSKPFPALEVVRKIGDDNAVYFGPYSSVQSVRSTIKQVNKIFKLRKCRDVQFANRTRPCLNYQINACLGACCNRVSRQEYARVVGDVILFLKGRAPDLINRLKFEMQTEADLEHFERAAQIRDTILAIQTTLERQVVVSTDRTDRDVIACAINGEKAVVTILFVRSGNLVGSRNYPFDTGLSGVPEILDAFVRHYYERSLFIPGQILIAEKIENHGLVQDLLIEKRGKRVSLVVPERGDKRRLVEMALVNAQKELEKNLSIQNEAWETLTALQTILGMSVYPRRIECFDNSNMAGTDPVSSMVVFVDGLACKSEYRKFIIRDAKENDDYACMTEVLTRRLSSTEAPLPDLLVVDGGKGQLSMAVAVLKSLGLENRFQVAGLAKKDAKLGEVYDKIYLPGRANPVNTRGALKALYLVQRLRDEAHRFAITFQRKRRSKRAGTSVLDAVPGIGKKRKQVLMTTYKGISRMGQATVEELASLPGMTLAAAQQVKSALALDKD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADTRP_HUMAN
Sequence: MTKTSTCIYHFLVLSWYTFLNYYISQEGKDEVKPKILANGARWKYMTLLNLLLQTIFYGVTCLDDVLKRTKGGKDIKFLTAFRDLLFTTLAFPVSTFVFLAFWILFLYNRDLIYPKVLDTVIPVWLNHAMHTFIFPITLAEVVLRPHSYPSKKTGLTLLAAASIAYISRILWLYFETGTWVYPVFAKLSLLGLAAFFSLSYVFIASIYLLGEKLNHWKWGDMRQPRKKRK
What is the function of this protein?
Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (PubMed:27018888).  Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids (PubMed:27018888).  Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro) (PubMed:21868574).
What are the official names of this protein?
Androgen-dependent TFPI-regulating protein, Fatty acid esters of hydroxy fatty acids hydrolase ADTRP, FAHFA hydrolase ADTRP.
What is the protein family that this protein belongs to?
Belongs to the AIG1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalized with TFPI and CAV1 in lipid rafts.
Protein: TIG_BURM9
Sequence: MANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFTISRAENLRVAGQPSFAPKEDTQQESAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGEHGDGGADTAAQNGDRVTVDFVGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKAGESREFDLKFPDDYHGKDVAGKTAQFTVTLKKVEWPHLPEIDADFAKSLGVEDGDLTKMRAEIKENLEREAKRRTQSIVKNQVMDALLKISELDVPKALIEQDQQRLVEMARQDLAQRGVPNAKDAPIPAEMFADQAERRVKLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASATAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: TORD_SHEB5
Sequence: MSQVDINHARALVYQLLSSLFAREVDEQRLKELTSEAAQQFWEQLSLEANFTQSVDKIRSTLNGIKDDEALLELAADYCGLFLVGTKHSASPYASLYLSGEDEPLLFGEQHQQMSEFLHQSKLQVQSHFPEPADHLAVMLAYMAHLCCHSEDSVQLSFLQTCVDSWLAKFINQLTQCHKNGFYSAVATLTLAWVKQDIAQLEPAVAVIS
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAS4_PRIMG
Sequence: MANNKSSNNNELLVYGAEQAIDQMKYEIASEFGVNLGADTTARANGSVGGEITKRLVQLAEQQLGGGRF
What is the function of this protein?
SASP are bound to spore DNA.  They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation.  They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.
What are the official names of this protein?
Small, acid-soluble spore protein C4, SASP.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: END4_STAEQ
Sequence: MLIGSHVSMSGKKMLQGSAEEAHKYGESTFMIYTGAPQNTRRKNIEDLNIEKGQQAMKTYGLSNIVVHAPYIINIANTTKPEVFNLGVDFLQKEIERTQALGAKDIVLHPGAHVGAGVDKGIQKIIEGLNEVLTHDNDVRIALETMAGKGTEVGRSFEEIAQIIDGVTHNDRLSVCFDTCHTHDAGYNVKEDFDGVLEKFDSIIGVDRIKVVHVNDSKNLRGAQKDRHENIGFGHIGFDALNYVVHHDTFKNIPKILETPYVGEDKKNKKPPYKLEIDMLKSQKFDPELKNKILTQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: MSCL_PASMU
Sequence: MSFVKEFREFAMRGNVVDMAVGVIIGGAFGKIVSSLVGDVVMPVLGILTGGVDFKDLSIVLKEAAGEVPAVTLNYGAFIQTVFDFVIIAFAIFLMIKALNKLKREEPKVEEPAEPKLSNEEVLLTEIRDLLKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTPAL_STAHJ
Sequence: MRKCFFMSHNPEEKQSNLDSNHKNESSSNKRIKFKTWQFILLLLGVVIITAGITVAATIGISHKISGLTKDERQEIKKIEYAYKTLNNDYYKKQNAGKLSEAAIDGMVKELKDPYSEYMTKDETKSFNEDVSGDFVGIGAEMQKKDKQIMITSPMKDSPAEKAGIQPKDVVTKVDGKSVVGKPLDQVVKLVRGKEGTTVKLTIKRGSQEKEIKIKRGKIHVKSVEYKKKDNIGVFTINKFQDNTAGELKSAIIKAHKDGVRSIVLDLRNNPGGLLDEAVKMANIFIDKDQTVVKLEKGDDTESIKTSNDASNEAKDMKVSILVNEGSASASEVFTGAMRDHKKAKVYGSKTFGKGIVQTTREFKDGSLLKYTQMKWLTPDGHNIHGKGIQPDTKIASPQYQSISVIPTDKSYSVGDNTKYVKSIKIGLDALGYNVNNDSKQFDTQLESAIKKFQSEHELSVNGKFDKKTNEKFTQLLVEKANKEDKVLDELINKLK
What are the official names of this protein?
Probable CtpA-like serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PFDB_HALSA
Sequence: MQGNLPPEAQEKLEQLQDLQEKAQNVATQKQQAEQQLSEAETALDALGDIEESTTMYREVGELLVETEYDNAHDDLDEKVSDLEVRVETLQKQEDRVQEQFESLQEELQDMLGGAGGAMGGGPGA
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_HYDS0
Sequence: MNYLAVLVGGGVGALVRYLVSIFIQKFVPNFPLGTMVINTTGAFLIGFLSIYLTEVIDAPPNIRLLLITGFLGGYTTFSTFTLEGIGLINNGDYLKAFYYIVGTNVIGFLFVALGRFLGGLL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3_ANOFW
Sequence: MGQKVNPIGLRIGIIRDWESRWYAEKDYADLLHEDLKIREYLTKRLSDAAVSRIEIERAANRVNITIHTAKPGMVIGKGGSEVEALRKALNELTGKRVHINIVEIKKPDLEAKLVAENIARQIENRVSFRRAQKQAIQRTMRAGAKGIKTMVSGRLGGADIARSEHYSEGTVPLHTLRADIDYATAEADTTYGKIGVKVWIYRGEVLPTKKKTEEGGN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL7_ANADE
Sequence: MADLNAIVEQLSGLTIMEAAELVKQLEEKWGVSAAAAPVMMAGGPAAAAAPVEEKTEFTVVLADAGANKINVIKEVRAITGLGLKEAKDLVEGAPKEVKAGVAKAEAEELKKKLEAAGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.