PharMolix/UniProtQA huggingface dataset:
Protein: EXO5_ASHGO
Sequence: MRTVRQRWATGWGRALHTSGSAPAGSSAESALLPEMGQLDPKVAAAPRRKYLSAKYRVVGKLFQQAENGGYLAYRKPAALENPYLDVQARPRVDGATGQIVYQGTPRLSVTRLLTKQWCELRTAYDLYSNMPLFESKAMRIGKRAHRKLENKLHGASDAAATQALERLQLAVPVDPLHRLAADWAGAIDRMCTLFQKGEARELLCHGYISADHGAFVEGPVREDSDVLVSGVIDHLVLTQRGGGSPLSALQPERSLQFPSDMAELVPFLKDLGERRAAEWEVVVGDIKTRKYTQVPSQASVVETSRLQVMYYRRFLEDLGADVDKAYEKLLTNAQRRGLDVDAPLAAGSAISVMEGIPQLGADMLRLVRGDPIGFGPFDSYNRYAAHDTYDFTQHAALLQDQPELQKYAVFFGQWKTPFNLRFLAARMAQLYGCIAPLLSNTLLIEYYMGGECFHVNTFKYDAAELRKHCEDSARFWFGKREIEPIEPTIRNVNAYCKFCDYKDICLWRKEAVLGWKSLGEELRGLP
What is the function of this protein?
Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MNME_CYTH3
Sequence: MSTTTVTNHTDTIVALASPQGIGAIGVIRLSGPQAFDITSSVFPSKNIAAVPTHTVHVGNIEDEGRILDEVVVTVFKGPKSFTKEDVVEISCHGSTFIVKELLQLLLRKGARHAKPGEFTMRAFLNGRFDLAQAEAVADLISSDSHASHQVALQQMRGGFSDEIRKLREQLIHFASMVELELDFSEEDVEFADRTQLRKLIHEIKRVIDRLIHSFSLGNVIKNGVPTVIIGKPNAGKSTLLNTLLNEEKAIVSEIAGTTRDFIEDELNVEGITFRFIDTAGLREATDAIEAMGVKRTREKMTQASLVIYLFDVKSTSERELIRDLEELKALKAPFLVVGNKIDKREDAIITTFRNIDGIIYISAKQNIGIEELKQNLLEIIQYESFKQNDTLVTNMRHYESLRETRKALDEVLTGMDSQVPGDLLAQDIRQSLFHLGEITGDISTDDLLDNIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACLB1_ARATH
Sequence: MATGQLFSRNTQALFYNYKQLPIQRMLDFDFLCGRETPSVAGIINPGSEGFQKLFFGQEEIAIPVHAAIEAACAAHPTADVFINFASFRSAAASSMAALKQPTIKVVAIIAEGVPESDTKQLIAYARANNKVIIGPATVGGVQAGAFKIGDTAGTIDNIIQCKLYRPGSVGFVSKSGGMSNEMYNTIARVTDGIYEGIAIGGDVFPGSTLSDHILRFNNIPQIKMVVVLGELGGRDEYSLVEAMKQGKVTKPVVAWVSGTCARLFKSEVQFGHAGAKSGGEMESAQAKNQALQDAGATVPTSFEALEVAIKETFDKLVEEGKVSPIKEVTPPQIPEDLSSAIKSGKVRAPTHIISTISDDRGEEPCYAGVPMSSIIEQGYGVGDVISLLWFKRSLPRYCTKFIEICIMLCADHGPCVSGAHNTIVTARAGKDLVSSLVSGLLTIGPRFGGAIDDAARYFKDACDRNLTPYEFVEGMKKKGIRVPGIGHRIKSRDNRDKRVELLQKFARSNFPAVKYMEYAVQVETYTLSKANNLVLNVDGAIGSLFLDLLAGSGMFTKQEIDEIVQIGYLNGLFVLARSIGLIGHTFDQKRLKQPLYRHPWEDVLYTK
What is the function of this protein?
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives.  May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids.  Required for normal growth and development and elongation of C18 fatty acids to C20 to C24 fatty acids in seeds.  In contrast to all known animal ACL enzymes having a homomeric structure, plant ACLs are composed of alpha and beta chains (By similarity).
What are the official names of this protein?
ATP-citrate synthase beta chain protein 1, ATP-citrate synthase B-1, ATP-citrate lyase B-1, Citrate cleavage enzyme B-1.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SCX9_MESMA
Sequence: MISFALLLMTGVESVRDAYIAKPENCVYHCATNEGCNKLCTDNGAESGYCQWGGRYGNACWCIKLPDRVPIRVPGKCHR
What is the function of this protein?
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin is active against mammals.
What are the official names of this protein?
Neurotoxin BmK-M9, BmK9, Bmk M9, BmkM9, BmK-IX.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARNA_ECOL5
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPRGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKSASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTERLLCEDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPL
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: TRI40_PANTR
Sequence: MIPLQKDNQEEGVCPICQESLKEAVSTNCGHLFCRVCLTQHVEKASASGVFCCPLCRKPCSEEVLGTGYICPNHQKRVCRFCEESRLLLCVECLVSPEHMSHHELTIENALSHYKERLNRRSRKLRKDIAELQRLKAQQEKKLQALQQWLGQLEHMPAEAARILDISRAVTQLSSLVIDLERTAKELDTNTLKNAGDLLNRSAPQKLEVIYPQLEKGVSELLLQPPQKL
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response.  Mediates inhibition of the RLR signaling pathway by ubiquitinating RIGI and IFIH1 receptors, leading to their proteasomal degradation.  Promotes also the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation.
What are the official names of this protein?
E3 ubiquitin ligase TRIM40, Probable E3 NEDD8-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: SSUB2_RHIL3
Sequence: MAPHPGKLKPATKAVHVRDLARRFATKTILDGVDLDIEEGEFVALLGRSGSGKSTFLRALAGLDHGVEGTGTLETPESLSVVFQDARLLPWRTVIQNVTLGLTGASGQEAGRKALAEVGLAGRETAWPNQLSGGEQQRVALARSLVREPALLLADEPFGALDALTRLKMHDLLRELCARHRPAVLLVTHDVDEAISLADRILVLDEGRLIEDLKIDLPTPRDHGDPRFAQFRIQLLSRLGVELPGRKAA
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS14_METEP
Sequence: MAKKSSVEKNNHRKDLVKRFAEKRKALLAIANDESREMEERFEARLKLAELPRNSSATRIRNRCEMTGRPRAYYRKLGISRVALRELGNRGLIPGLVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: HLY1_AERSA
Sequence: MNIKKLSLCIFFATTQVHAFTQWGAGGITPMGHEWLTRTSALEVLNAEHKTSVDPNDPRNTWTSGLAKNIDISTADDEVAKIKSHTNDNSLYAPRSDAVYSAIVGQRWVDLGGMNVANNLISQTGPDCFDAVSQEPADIQQDHFMRRYDDNGQQGGVKSAQRGQERFITHFINAAMATNKRIVVWDGGGSSAKTDVDYNYFLFGRAVHLFQDSFSPEHVVRSPSDNYEKVRQVKAYICTEGAEQHAHSTGAVLDYTSGDVIWKVGTKTDTGWGGYKASNMKPVALVAMEASKDLWAAFMRTMSVDINEREKYARNEAQVLIDKWMSFDKDEMEHWYDNENNRDNTYVKVDGDTGKGKLQKECMSGLSAKNRYGATIKPKTQKELVDVLDDSRRYCLFNIEAEPGYADANDPYLNIPFNWRWKSNSWLVPNASWQQKQLDRDTGKIIKIKEFTNNQELTVDSIENNYSIVTGAKKPLSLVRVPGDGGKSFYLRSKDNPYLFFSYSDKKNGRIKLWHSPNQAEFEILPGNNIFNLKNTYWNQYVWYDKNSKGAYLTEKGSPDNASSKWIISEEN
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.
What are the official names of this protein?
Hemolysin-1.
Protein: NS2_MYCTU
Sequence: MDETIVTDKGVAEFSFFKF
What are the official names of this protein?
30 kDa non-secretory protein 2.
What is the protein family that this protein belongs to?
To C.elegans F20A1.4 and H.influenzae HI_0967.
Protein: LSM6_KLULA
Sequence: MESKATASGSFLENIIGKPVYVKLFSGILYQGKLESIDGFMNVTMSQVSEHYEAEENGTLHKYPSEVFLRGSQVLYISEK
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates.  Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6. U5 tri-snRNP, and free U6 snRNP).  It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm6.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: XDH_CHICK
Sequence: MAPPETGDELVFFVNGKKVVEKDVDPETTLLTYLRRKLGLCGTKLGCGEGGCGACTVMISKYDPFQKKILHHTANACLFPICALHHVAVTTVEGIGNTKSRLHPAQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPKPKMEDIEDAFQGNLCRCTGYRPILEGYRTFAVDSNCCGKAANGTGCCHSKGENSMNGGCCGGKANGPGCCMNEKENVTMMSSSLFDSSEFQPLDPTQEPIFPPELMTQRNKEQKQVCFKGERVMWIQPTTLQELVALKSQYPNAKLVVGNTEVGIEMRLKNMLYPVILAPAWIPEMNAVQQTETGITFGAACTLSSVEEVLRKAVAELPSYKTEIFQAALEQLRWFAGPQIRNVAALGGNIMTASPISDLNPVLMASGSKLTLISMEGKRTVMMDEKFFTGYRKTIVKPEEVLLSVEIPYSKEGEYFSAFKQAYRREDDIAIVTCGMRVLFQHGTSRVQEVKLSYGGMAPTTILALKTCRELAGRDWNEKLLQDACRLLAGEMDLSPSAPGGMVEFRRTLTLSFFFKFYLTVLQKLSKDQNGPNNLCEPVPPNYISATELFHKDPIASTQLFQEVPRGQLVEDTVGRPLVHLSAAKQACGEAVYCDDIPHYENELYLTLVTSTQAHAKILSIDASEAQSVPGFVCFVSAKDVPGSNITGIANDETVFAEDVVTCVGHIIGAVIADTQEHSRRAAKAVKIKYEELKPIVTIQEAIEQQSFIKPIKRIKKGDVNKGFEESDHILEGEMHIGGQEHFYLETHCTLAVPKGEDGEMELFVSTQNLMKTQEFTASALGVPSNRIVVRVKRMGGGFGGKETRNTILTTVVAVAAFKTGRPVRCMLDRDEDMLISGGRHPFLGRYKVGFMKNGKIKSLEVSYYSNGGNSADLSHGVMDRALLHLDNSYNIPNVSIMGFICKTNLSSNTAFRGFGGPQGMMIAECWMSDLARKCGLPPEEVRKINLYHEGDLTHFNQKLEGFTLRRCWDECLSSSNYHARKKLIEEFNKQNRWKKRGMCIIPTKFGISFTVPFLNQAGALVHVYTDGSVLLTHGGTEMGQGLHTKMIQVASRSLGIPTSKIYISETSTNTVPNTSPTAASVSADINGMAVHNACQTILKRLEPIKQSNLKGSWEDWIKTAYENCISLSATGFYRIPDVGYNFETNKGKPFHYFSYGVACSEVEIDCLTGDHKNIRTDIVMDVGTSLNPAIDIGQIEGAFVQGIGLFTMEELRYSPEGNLYTRGPGMYKIPAFGDIPTEFYVSLLRDCPNSKAIYSSKAVGEPPLFLSASVFYAIKDAIYSAREDSGVTEPFRLDSPATPERIRNACVDTFTKMCPSAEPGTFKPWSVRA
What is the function of this protein?
Key enzyme in purine degradation.  Catalyzes the oxidation of hypoxanthine to xanthine.  Catalyzes the oxidation of xanthine to uric acid.  Contributes to the generation of reactive oxygen species.
What are the official names of this protein?
Xanthine dehydrogenase/oxidase.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome. Cytoplasm.
Protein: HO_PORPU
Sequence: MVSSLANELREGTTKSHSMAENVSFVKSFLGGVVDKKSYRKLIANLYFVYSAIEEEILLNKDHPAIKPIYFTELNRKTSLAKDLNYYYGPDWLNIIEPSSATQVYVNRIHNIGNKQPELLVAHAYTRYLGDLSGGQVLKKIARGAMNLSDERGTKFYDFDEIEDDKIFKNNYRSALDTIPLSDEQVQNVVAEANISFTLNMKMFEELNSSIVKIITMIIVSTVRKFTLKSILATAD
What is the function of this protein?
Catalyzes the opening of the heme ring with the release of iron.  Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae.
What are the official names of this protein?
Heme oxygenase.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TXP1B_BRASM
Sequence: IIECVFSCDIEKEGKPCKPKGEKKCSGGWKCKIKLCLKI
What is the function of this protein?
Inhibits voltage-gated calcium channels (Cav) in rat cerebellar granule cells (By similarity).  Has insecticidal activity (By similarity).
What are the official names of this protein?
Omega-theraphotoxin-Bs1b, Omega-TRTX-Bs1b, BsTX1b, Venom protein 1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 06 (TXP1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_STRT1
Sequence: MSKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGGLGGFGGMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYVATGKNEPAKLEQVIAGVAEGCVQSGVALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVAEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGQKLKDVLLEPTRIYVKAALPLIKEELVNGIAHITGGGFIENVPRMFSDDLAAEIDESKVPVLPIFKALEKYGEIKHEEMFEIFNMGIGLMFAVKPENVERVKELLDEPVYEIGRIVKKDGASVVIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_ECOL5
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALPQYLQDALASQPS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S12_NAJNI
Sequence: MICHNQQSSQRPTIKTCPGETNCYKKRWRDHRGTIIERGCGCPSVKKGVGIYCCKTDKCNR
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 2, Neurotoxin beta.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EMAL_DROME
Sequence: MPQISPNAPLEGNVSPPPTQPHLDDNLHNGNGNGNGIHSSSSNINKHGSNINGNNDSNRSSPAKSPKRPVSSSFRIQNTSRYDNDEEDLAASEQVAGGDRQVPDYWQQRNGATTGATSGRQSRAISPGYLDNMSENSEQPPVVPLVRSKSRPEISSAAASRYNNLSYWKARRVVFYRNGDPFFPGVELRYRPGRDVTSLDNLLDKISPKMDLPRGARYVFSMDGDRKYHLDELEDGAFYVVSSFKAFKPASYGKKNGMWYASPGNQGWGSKPASRKPSIMEADLGTLSTTSGSIKRSAGRVIRIINNLDHSVQCRVLLNLRTSQPFEEVLEDLGQVLKINGAKKMYTGTGQEVRSFSQLRNEFADVDTFYLATGTALIAGSPIRRSRSRPSVVAAAPILPTDELPKVPLRGARPRSKSRPRILYAPESEILRPNGEYTMLDIMKEEPTKVTIRGLRRTFYPPVHHAPADNSPPDKKLQLQWVHGYRGIDARRNLWVLPSGELLYYVAAVAVLFDRDEDAQRHYTGHTEDIMCMDVHPSRELVASGQKAGRDRKSQAHVRIWSTESLQTLYVFGMGELDSGVTAVAFSQLNGGSYILAVDSGRESILSVWQWQWGHLLGKVATLQEGLSGAAFHPLDDNLIITHGRGHLAFWHRRKDGFFERTDIVKQPSRSHVTSVQFEPDGDVITADSDGFITIYSVDSDGAYFVRTEFEAHNKGIGCLIMLGEGTLLSGGEKDRKIAAWDSLQNYKKIADTKLPEAAGGVRTIYPQRPGRNDGNIYVGTTRNNILEGSLQRRFTQVVFGHGRQLWGLAAHPDDELYATAGHDKHVALWRKNKLIWTIQTGYECVALAFHPFGTLAAGSTEGHLLVINCENGAVMLTLRVCGSPLNCVAYNQVGDMIAMGSQNGSIYLFRVSRDGFSYKKVNKIRGSQPLTHLDWSMDGNFVQTVTIDFDLLFWDAKSLSPERSPIAMKDVKWLTNNCTVGFLVAGQWSNRYYSTTNTIVATCSRSAAHDMLASGDAEGYLRLFRYPCISPRAEFHESKVYSGMLACVRFLCGDHTLITVGGTDASLMVWDIVEE
What is the function of this protein?
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
What are the official names of this protein?
Echinoderm microtubule-associated protein-like CG42247.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EMAP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: 3BP2_HUMAN
Sequence: MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
What is the function of this protein?
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways.  Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
What are the official names of this protein?
SH3 domain-binding protein 2, 3BP-2.
Protein: ZFAN6_RAT
Sequence: MAQETNHSQAPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPAASVSSLSESLPVQCADGSVPDAQSALDSTSSSMQPGPVSNQSLLSESVAPSQVDSTSVDKAVSETEDLQGPRAEGLVPLECDPPSSVSDTTQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI
What is the function of this protein?
Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis.  Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1.  Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6.  In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).
What are the official names of this protein?
AN1-type zinc finger protein 6, Zinc finger A20 domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCA5_TRYBB
Sequence: MDAALALLFGQVATAVLPYVVNSIGRVPRPKRVDVKKAMGEAHQCRPVVPYRAPRPYTEGRVKALFIGINYTGSSAQLGGCVNDVMHMLQTLQRIEFPISECCILVDDRRFPNFTAMPTRENIIKYMAWLVYDVRPGDVLFFHFSGHGAETKGGRDSNEKMDQCLVPLDYDKAGAILDDDLFELMIKGLPAGVRMTAVFDCCHSASLLDLPFAFVAGRNVSSNQRHEMRMVRKDNYSRGDVVMFSGCEDSGTSADVTNTSSFGNGTVAAGGAATQAFTWALLNTTGYSYIDIFMKTREVLRQKGYKQVPQLSSSKPVDLYKQFSLFGPLTMNASLVQHLPQEYVQPWAPHPAYQQPHEATLPASVSQPHSQPVMGIPVASTSNGKSNPGVSDGGRASGEVYPPTQYPSSHPAPQQQAYYQPPQQAYYQPPQQAYYQPPQQAYYQPPQQAYYQPPQQAYYQPEPHHQPAPPPPPKKENKPARPGYPMSYCMKFSQGKPGRK
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine or lysine residues.
What are the official names of this protein?
Metacaspase-5, TbMCA5.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
What are the subcellular locations of this protein?
Recycling endosome. Note=Localizes to RAB11-positive recycling endosomes.
Protein: ENGB_SHEB8
Sequence: MTESRIDFRRAKFLISAPDIAHLDQYLPGDVGVEIAFAGRSNAGKSSALNALTEQKSLARTSKTPGRTQLINVFELDAQRRLVDLPGYGFAQVPLALKNKWQQALGEYLQKRACLSGVVVLMDIRHPLKDLDMQMIEWAVASEIPVLALLTKSDKLAQSAKMKTVNEVRLALSEFGDWVQVEPFSSLKGTGKPKVLAILNEWCHPQWLTDELDAANNAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ASSY_MYCUA
Sequence: MSERVILAYSGGLDTSVAISWIGEETGREVVAVAIDLGQGGEDMEVVCQRALDCGAVEAVVVDARDEFAEGYCLPTILNNALYMDRYPLVSAISRPLIVKHLVEAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDVYSYTEDPTVNWNTPDEVIVGFERGMPVSIDGNAVTMLQAIEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHAELEHVTLERELARFKRHTDQRWAELVYDGLWYSPLKTALESFVAKTQEHVSGEIRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDTFDQSAAKGFVYVHGLSSKLSARRDLQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALX3_HUMAN
Sequence: MDPEHCAPFRVGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT
What is the function of this protein?
Transcriptional regulator with a possible role in patterning of mesoderm during development.
What are the official names of this protein?
Homeobox protein aristaless-like 3, Proline-rich transcription factor ALX3.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KATG_NEUCR
Sequence: MSECPVRKSNVGGGGTRNHDWWPAQLRLNILRQHTPVSNPLDKDFDYAAAFKSLDYEGLKKDLTKLMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRVTDGRGGGGEGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGNKISWSDLLLLTGNVALESMGFKTFGFAGGRPDTWEADESVYWGAETTWLGNEDRYSEGQEGHEGHGVVQGDESKKQHTDIHNRDLQSPLASSHMGLIYVNPEGPDGIPDPVASAKDIRVTFGRMAMNDEETVALIAGGHSFGKTHGAGPTHHVGKEPEAAPIEHQGLGWANSFGQGKGPDTITSGLEVTWTPTPTKWGMGYLEYLYKFDWEPTKSPAGANQWVAKNAEPTIPDAYDPNKKKLPTMLTTDIALRMDPAYDKICRDYLANPDKFADAFARAWFKLLHRDMGPRTRWIGPEVPSEILPWEDYIPPVDYQIIDDNDIAALKKEILATGVAPKKLIFVAWSSASSFRGSDKRGGANGARIRLAPQNEWKVNDPSTLREVLAALESVQQKFNDSSSGKKVSLADLIVLGGVAALEQASGLVVPFTPGRNDATQEHTDVHSFTHLEPHADGFRSYGKGTKRVRTEQFLIDRASLLTLSAPELTALIGGLRVLEANYDGSSYGVLTKTPGKLTNDYFVNLLDTNTAWKAADNEGEVFIGYDRKTHDKKWTATRADLIFGAHAELRALAEVYAAVDGEEKFKRDFVAAWHKVMNLDRFDLKQEGRGQNAPKL
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Catalase-2, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.