PharMolix/UniProtQA huggingface dataset:
Protein: PALS1_HUMAN
Sequence: MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR
What is the function of this protein?
(Microbial infection) Acts as an interaction partner for human coronaviruses SARS-CoV and, probably, SARS-CoV-2 envelope protein E which results in delayed formation of tight junctions and disregulation of cell polarity.
What are the official names of this protein?
Protein PALS1, MAGUK p55 subfamily member 5, Membrane protein, palmitoylated 5, Protein associated with Lin-7 1.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Golgi apparatus. Cell membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Cell junction, tight junction. Cell junction, adherens junction. Cell projection, axon. Perikaryon. Apical cell membrane. Note=Localized to the tight junctions of epithelial cells (By similarity). Localized to the Golgi apparatus in T lymphocytes (PubMed:21479189). Localized to a subset of intracellular vesicles (By similarity). Localized to the Purkinje cell body and axon (By similarity). Localized to intercellular junctions in vascular endothelial cells (PubMed:27466317). Localized to Schmidt-Lanterman incisures, the adaxonal domain, and the inner part of paranodal loops in myelinating Schwann cells of the sciatic nerve (By similarity). Localized to apical membrane domains of the outer limiting membrane (OLM) junctions in the retina (By similarity). Colocalizes with CRB1 at the OLM, apical to the adherens junction (PubMed:15914641). Colocalizes with MPP1 in the retina at the OLM (PubMed:17584769). Colocalizes with MPP3 to the subapical region of adherens junctions in the retina OLM (PubMed:16519681). SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus. Note=(Microbial infection) Following infection by human SARS coronavirus, partially localized at the site of viral replication; the endoplasmic reticulum-Golgi intermediate compartment, reducing its levels at cell-cell contacts which results in delayed formation of tight junctions and affects establishment of cell polarity.
Protein: SYR_BURMS
Sequence: MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAKPLGANPRQLAEQIVAALTAQPEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRAFGASERDHDKRVLLEFVSANPTGPLHVGHGRQAALGDALANVLASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRDVEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYEQEGALWLRTTDEGDDKDRVMRKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTIARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISKRAGSYVTVRDLIEWSGGATPGSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARICSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFYLRELASEFHSFYNAERVLVDEQAPRTARVALLAATRQVLENGLAMLGVSAPSKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCR1_CANAL
Sequence: MLTHHLSKLATPKFLVPFAGATALSIGLALQYSTSNNYIANETGKTFTDSNEWVDLKLSKSIDLTHNTKHLVFKLKDENDVSGLITASCLLTKFVTPKGNNVIRPYTPVSDVNQSGEIDFVIKKYDGGKMSSHIFDLKEGETLSFKGPIVKWKWEPNQFKSIALIGGGTGITPLYQLLHQITSNPKDNTKVNLIYGNLTPEDILLKKEIDAIASKHKDQVKVHYFVDKADEKKWEGQIGFITKEFLQKELEKPGSDFKVFVCGPPGLYKAISGPKVSPTDQGELTGALKDLGFEKEHVFKF
What is the function of this protein?
May mediate the reduction of outer membrane cytochrome b5.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, Mitochondrial cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: ASSY_XANCP
Sequence: MSSKDIVLAFSGGLDTSFCIPYLQERGYAVHTVFADTGGVDAEERDFIEKRAAELGAASHVTVDGGPAIWEGFVKPFVWAGEGYQGQYPLLVSDRYLIVDAALKRAEELGTRIIAHGCTGMGNDQVRFDLAVKALGDYQIVAPIREIQKEHTQTRAYEQKYLEERGFGVRAKQKAYTINENLLGVTMSGGEIDRWEAPGEGARGWCAPRSAWPTEALTVTLKFVEGEAVALDGKALPGAQILAKLNTLFAQYGVGRGVYTGDTVIGLKGRIVFEAPGLISLLTAHRALEDAVLTKQQNRFKPDVARKWVELVYEGFYHDPLKTDIEAFLKSSQSKVNGEVTLETRGGRVDAVAVRSPHLLNAKGATYAQSADWGVEEAEGFIKLFGMSSTLYAQVNR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EGLX_ARTBC
Sequence: MRTTGLLLLGALAELGSATYILEDDYQPNTWFDQFRFFSAKDPTHAYVNYLDQAEARSQNLIGVRNNAVYLGVDHKNVATGEGRSSVRLETKKVYNHGLIVADINHMPGGECGTWPAFWTTSSAWPMEGELDIIEGVNQQKQNDYALHTAQGCSIPERGDFTGSVVTPNCDVKALGQAENQGCLVEDTKGSRGYGPDFNNATGGVFATEWTDQAISIWFFPREDIPKDVNSEHPDPSKWGKPSAFFGGGECPIGKHVRNQRIIFNTAFCGGWADGMWPGDPICSKKAPTCMEYVRENPSAFEDAYWSINYMKVYQQGTAPTKPSQAPAPPSSTPALPTMKSTSTVSSMVSATQPAPTASNPTGAPMQPSSSSSNNGPQPTGGNGNPGDSCPPPTQPACRTYVTTKTYTLVSTMMPSGPQTTGGIVPVPSAALEDIKDTAQRLRRRDMERHSRRGHHN
What is the function of this protein?
Mixed-linked glucanase involved in the degradation of complex natural cellulosic substrates.  Active on laminarin.  lichenan, soluble carboxymethyl cellulose but not on pustulan.
What are the official names of this protein?
Endo-1,3(4)-beta-glucanase ARB_04519.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1229_PSEE4
Sequence: MSVSVCPCGTGNLLDACCGHYHAGTPAPDAQSLMRSRYSAYVLGLVDYLVGTTLPAQQPGLDRAGMAAWSAQSTWLGLEVESAEVFGGQPEHAFVTFTARWHDTDGDHQHRERSAFVQHAGRWYFIDPTVPLNAGRNDPCPCASGQKFKKCCASYLGS
What are the official names of this protein?
UPF0225 protein PSEEN1229.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: GCSH_METNO
Sequence: MLRFTEEHEWLKLDGEIATVGITSHAAEQLGDLVFVELPKVGAVLTKGEAAAVVESVKAASDVYAPLDGEVTEINEAVVAAPETVNADPQGAGWLYRMRLKDPSAMEALMDEAAYAAFPK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RS7_MYCA1
Sequence: MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLKGKKSLAERIVYGALENAREKTGTDPVITLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWLVSFSRQRREKTMVERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS9_CERSK
Sequence: MSDIKSLDDLKSVVGEAPVAEVAIAREPVRDSLGRSYATGKRKDAVARVWIKPGSGKVTVNGKPMDEYFARPVLQMILRQPFKVANVEGQFDVMATVAGGGLSGQAGAVKHGISKALQLYEPALRAALKAAGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: LPXK_FLAPJ
Sequence: MNFLRKTLFPFAILYGFITSIRNFLFDCGILKSHAFPIPVIAVGNLSVGGTGKTPQIEYLIRLLSNKYQIATLSRGYKRKSEGFILANPTSNAEILGDEPFQFYKKFPNIQVAVAANRKNGIERLLSLPNKPEIILLDDAFQHRKVKAGFYILLTAYNDLFINDFMLPTGNLRESRSGAKRANMIIVTKCPKDISELAQNKIKEALINYNNKKAEVFFTFIDYDDKIYSANKALNVNEVKTASKLLLAGIAKPESFFAHLQSQNDECLVYPDHHHFLEKNITDIKEKAKNKIIITTEKDFVRLSEKLNSDNLFYLPIKSLFVNNEKKFDKKIINYVESSTTNG
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: IDI2_STAAU
Sequence: MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVNDIDLTSQTPDLTMTYPVYINAMTGGSEWTKNINEKLAVVARETGLAMAVGSTHAALRNPRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPEGNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNFVDIENERRANKDMDYLSSWGQSTVESLLETTAYQSEISVFASGGLRTPLDAIKSLALGAKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPEILSWIEQRNLNIHRG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_BUCDN
Sequence: MPKYRSFKTTHGKNMSGARSLWRATGMNDEDFKKPIIAIVNSFSQFVPGHIHLKKVGELISDQIQKSGGVPKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYVINAHCVDAMICVSNCDKITPGMLMAALRLNIPSVFISGGPMEAGKIRKNEKEIKIDLVDAIMIGGQSNQCKNFIKEVELLACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGTLLATHVDRKNLFIKSAKTIVKITKEYYHHNNKKVLPRSIASKESFENAMILDIAMGGSTNTILHLLAAAQEAEIDFNMSNIDELSRKIPHICKVSPSTSLYHMEDVHRAGGVMGILGELNRANLLNKQTQNILQLNLEETLKEYDIVLSKNPDILKMFKAKPAGIRTIQPYSQENRWLTLDYDRKTGCIRSCKNAYSQDGGLAVLYGNLAKNGCIIKTAGIKKSNYIFSGPARVYESQEEAVNAILKGEIISGDIVVIRYEGPKGGPGMQEMLYPTTYLKSMKLDKTCALITDGRFSGGTSGLSIGHVSPEAANKGVIALVKNGDIINIDITQRVINLNITEQELQQRIFQEESKKSLSYKPLNRKRHISYALKTYAFFAMSADKGAVRDRQKLSKI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: NPHP3_XENTR
Sequence: MGTASSLVNPGEVIEDTYGGGGGEACVIPVEVKPKARLLRSSFRRGPRVIGASFKSTASVDLEYAAEYERLKKEYEIFRVSKNNEIASMQKKEVKLDEENKRLRAELQALQKTYQKILREKESAVEAKYQAMERAATFEHDRDKVKRQFKIFRETKEKEIQDLLRAKRDLEAKLQRLQAQGIQVFDPGESDSDDNGTELTVPGTQCEYWTSGGLGSEPSIGSMMQLQQSFRGPEFAHSSIDVEGPFANVNRDDWDAAVASLLQVTPLFSQSLWSNTVRCYLMYTAETQAEVKIFLKEYSPKLQRMCETSGYFFQVTFFPEECENQYFAVRKWEIEKSSIVILFICSSLPSCLQEDCEEAFLKNTEAKPCLIYHRIEDGRSDSEGLKQLLEQDTNKANKTKIVDHYGDPVEGANKIYCQLEQVINQDLLGIEITDPNAKDDSATKEEDDFWDVLWDVHDEQEQMEAFQQASHSICELGFQKYYDRLNDLVAAPAPIPPLLISGGPGSGKSLLLSKWIQLQQKHSPNTLMLYHFVGRPLSSSSEPSLMIKRLFLKLMQHSWSVSSLSLDPAKFLEEFPHWLEKLSIRYQGNIIIIIDSIDHIQQSEKHMKWLIDPLPVNVRVIVSVNVETCPQAWRLWPTLHLDPLNSKDVKSLINMECGRANIILTKEQERKLERHCRSATTCNALYVTLIAKLLTWAGSTGNIDDVLQLCLQCQDTVSLYRLALHSVQEVMPSAKDKEFMREILCFISASRNGVSECELMELCPGLTWPVLTSLIFHLYTLVLLKYSCGLIQFQHLQEILSFNILNFKAWDAVNLEYMQGDQSIISEYREKLIQHFNAQLSCDRVTWRSADELTWLYQQQGEKQKLHRCLMNLFVSQNLYKRGHFAELLSYWQLVGKDKISMASEYFDALKQYERSCEGEEKMTSLADLYETLGRFLKDLGLLSQAVTPLQRSLEIRETALDPDHPSVAQSLHQLAGVYVQSKKFGNAEQLYKQALEISENAYGSEHMRVARELDALAVLYQKQNKFEQAEQLRKKSLKIRQKSARRKGSMYGFALLRRRALQLEELTLGKDTSDNARTLNELGVLYYLQNNLETAETFLKRSLEMRERVLGADHPDCAQSINNLAALYNEKKQYDKAEELYERALDIRRRALSPDHPSLAYTVKHLAVLYKRKGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYCQMKKQAEASPLYERAMKIYEDSLGRMHPRVGETLKNLAVLRYEEGDFEKAAELYKRAMEIKETETSVLGAKAHSGHSSSGGDTYSVQNALPVCAFPE
What is the function of this protein?
Required for normal ciliary development and function.  Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling that regulates planar cell polarity.  Probably acts as a molecular switch between different Wnt signaling pathways.  Required for proper convergent extension cell movements (By similarity).
What are the official names of this protein?
Nephrocystin-3.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: MAM4_SCHPO
Sequence: MGNLHTSIAVASICLTSAFLGCVFGLGFFVWIIYGYSIGGFFAFLSLFHLLEFYITARFQGSQLSWDSFILNNGKAYWLAMLVGLLECLLSGGKSFAKVINCLRFPSFLINFIFSVYQTSALGFLCLGQYLRSSAMVQAGQSFSHIVASKRNKDHLLVTDGIYAYVRHPSYVGFFIWALGTQMLLGNFVSTLLFSLVLWKFFSQRITTEEAYLVSFFGDSYEQYRKKVPSGIPLIP
What is the function of this protein?
Mediates C-terminal methylation of the isoprenylated C-terminal cysteine in M-factor.
What are the official names of this protein?
Protein-S-isoprenylcysteine O-methyltransferase, Isoprenylcysteine carboxylmethyltransferase, Prenylated protein carboxyl methyltransferase, PPMT, Prenylcysteine carboxyl methyltransferase, pcCMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPF1_YEAST
Sequence: MTKKSFVSSPIVRDSTLLVPKSLIAKPYVLPFFPLYATFAQLYFQQYDRYIKGPEWTFVYLGTLVSLNILVMLMPAWNVKIKAKFNYSTTKNVNEATHILIYTTPNNGSDGIVEIQRVTEAGSLQTFFQFQKKRFLWHENEQVFSSPKFLVDESPKIGDFQKCKGHSGDLTHLKRLYGENSFDIPIPTFMELFKEHAVAPLFVFQVFCVALWLLDEFWYYSLFNLFMIISMEAAAVFQRLTALKEFRTMGIKPYTINVFRNKKWVALQTNELLPMDLVSITRTAEESAIPCDLILLDGSAIVNEAMLSGESTPLLKESIKLRPSEDNLQLDGVDKIAVLHGGTKALQVTPPEHKSDIPPPPDGGALAIVTKTGFETSQGSLVRVMIYSAERVSVDNKEALMFILFLLIFAVIASWYVWVEGTKMGRIQSKLILDCILIITSVVPPELPMELTMAVNSSLAALAKFYVYCTEPFRIPFAGRIDVCCFDKTGTLTGEDLVFEGLAGISADSENIRHLYSAAEAPESTILVIGAAHALVKLEDGDIVGDPMEKATLKAVGWAVERKNSNYREGTGKLDIIRRFQFSSALKRSASIASHNDALFAAVKGAPETIRERLSDIPKNYDEIYKSFTRSGSRVLALASKSLPKMSQSKIDDLNRDDVESELTFNGFLIFHCPLKDDAIETIKMLNESSHRSIMITGDNPLTAVHVAKEVGIVFGETLILDRAGKSDDNQLLFRDVEETVSIPFDPSKDTFDHSKLFDRYDIAVTGYALNALEGHSQLRDLLRHTWVYARVSPSQKEFLLNTLKDMGYQTLMCGDGTNDVGALKQAHVGIALLNGTEEGLKKLGEQRRLEGMKMMYIKQTEFMARWNQPQPPVPEPIAHLFPPGPKNPHYLKALESKGTVITPEIRKAVEEANSKPVEVIKPNGLSEKKPADLASLLLNSAGDAQGDEAPALKLGDASCAAPFTSKLANVSAVTNIIRQGRCALVNTIQMYKILALNCLISAYSLSIIYMAGVKFGDGQATVSGLLLSVCFLSISRGKPLEKLSKQRPQSGIFNVYIMGSILSQFAVHIATLVYITTEIYKLEPREPQVDLEKEFAPSLLNTGIFIIQLVQQVSTFAVNYQGEPFRENIRSNKGMYYGLLGVTGLALASATEFLPELNEAMKFVPMTDDFKIKLTLTLLLDFFGSWGVEHFFKFFFMDDKPSDISVQQVKIASK
What is the function of this protein?
Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum (PubMed:22918956, PubMed:32973005).  Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane (PubMed:32973005).  Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains (PubMed:32973005).
What are the official names of this protein?
Endoplasmic reticulum transmembrane helix translocase, Complexed with DOR1 protein 1, Endoplasmic reticulum P5A-ATPase, Sensitivity to the P.farinosa killer toxin protein 1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to endoplasmic reticulum regions devoid of phosphatidylinositol 4- phosphate (PI4P) hydrolytic machinery.
Protein: RS13_LACDA
Sequence: MARIAGVDLPRDKRIVIALTYIYGIGEHTAQEICAAAGVSEDVRSKDLTPEQQEKLRAEVDKYRVEGDLRREVSMNIKRLVDIGSYRGIRHRRGLPVRGQNTKNNARTRKGAKRSR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL27_NOSS1
Sequence: MAHKKGTGSTRNGRDSNAQRLGVKRFGGQAVIAGNILVRQRGTKFHAGNNVGIGKDDTLFALVDGVVTFERKGKSRKKVSVYPAAAAEAVAS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y967_HAEIN
Sequence: MQNSSNIFTTDKAANEFSFPDLKNFRYNDRTFLR
What are the official names of this protein?
Uncharacterized protein HI_0967.
Protein: TATA_ACIAC
Sequence: MGSFSIWHWLIVLLIVVMVFGTKKLKNIGSDLGGAVKGFKDGMKDGSTPEGTPASTTAATPPAGQVTNQQAHAADPGTIDVEAKHKG
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PCKG_SULAC
Sequence: MKVDLSPLNGIISDKAFQKLKSINNPSLVHFLSKTIELTTPDRVYVSFGEEKDREYVKKRALETKEEIKLKMEGHTIHFDHPLDQARAREDTFILTDEKIPFVNTKPRDEGLREMLSLLKGSMKGREMYVGFYSLGPRNSKFSILAVQITDSPYVIHSENILYRNAFEDFYGDKPFLKFIHSKGQLDIKKRRIMIDVKENTVYSVNTTYAGNSVGLKKLALRLTVTKAVNEGWLSEHMAIVGFEGNRGTHYFTASFPSGSGKTSTSMLGSLISDDLAFIKEIDGVCRAVNPEIGIFGIIQGINERDDPVIWDVLHKPGEVIFSNVLMTDDGGVYWEGSEVEKPEKGYNYEGAWTKESGKPASHPNARFTSPLTSFSNLDKDYDNPQGVVIDGIIFGVRDYSTLVPVTEAFSWEHGVITIGASMESSRTSAVIGKADVLEFNPMAILDFMPLSLGKYLNNYLTFGRNLKYVPKIFSFNYFLKDENNKFLNSKEDKRVWVKWAVKRVESETDAIYTPVGFIPYYEDLSKLFNSTLGKQYTKEAYELQFTLKLSKYLEKTERIMKIYSEIADTPIEVINELKAQKDRLLDYINRYGDKVSPFQLVKS
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_PSEF5
Sequence: MRIGHGYDVHRFAEGDFITLGGVRIAHHFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVVALIHAKGWKIGNVDNTIVAQAPKMAPHIETMRALIAEDLQVELDQVNVKATTTEKLGFVGREEGIAVHSVALLQRP
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RPOC_LEPIN
Sequence: MRSHNDFESITIRLASPERIKEWSYGEVKKPETINYRTLKPEKDGLFCEKIFGTTKDWECYCGKFKSIRYKGVVCDKCGVEVTHSKVRRERMGHIELAAPVSHIWYYRSVPSRMGLLLDMTVNQLKSVLYFEKYVIIDPADSGRNRGELIDEEEYHGYLDEYGDKFVAGIGADAIKELLARIDVDAEARMIRQKIQDKDKISDKRILKRLEVLEAFRDSGNRPEWMVLDIVPVIPPELRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLALKAPEIIVRNEKRMLQEAVDALFDNSRRKRAVKGKGNRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKYHEMGLPKKMALELFKPFIMKRLVDLDLAPNIKSAKKKVEAEDKEVFDVLEYVVKEHPVMLNRAPTLHRLGIQAFLPVLVEGKAIKLHPLVCHAFNADFDGDQMAIHVPLTPKAQLETWMLMLSPHNILNPANGHPICGPTQDIVLGIYYLTSELPSEPGVPLKSFSNLEEVHYAIDRGVVEFRTKISVYHQGKILETTPGRLIFNTILPEGYAYVNRPLSDKETNRIIADVYDKYGPAKTVLMLDDIKKLGYRYATLFAPTISIEDIRVSPGKVGLVGDANKEVEKADSEYRKGIITNEERRKKVIEIWTKTNDLITESMFKELEKDKGGFNPVFIMAASGARGSKQQIRQLAGMRGLMAKPSGEIIELAIRSNFREGLSVLEFFISTHGARKGLADTALKTADAGYLTRRLVDISQDVIISEDDCGTEESISLGVVKEGENVIVSLNDRVFGRYTAEDVIDPVTDQVVYPRNTLITREVGQKVENLGYDKIRVRSPLTCESKQGVCIRCYGMDMARLIPAEIGEAVGTIAAQSIGQPGTQLTMRTFHIGGAASAKVQEKEHKVSYTGIVNNINGRLITNEKSQSVFSRRGSIVIQRLIQQYKTEELSNLRVENGQKVDKGELVATSPAGENITSEMPGTIHIENGLFRILGEEAVIPVKTGTIVNVKVNDITQPNQPLAEFDPYNEVGISEIDGTVQWMDLEIGKNVRRDEDLRTSNILLKVIEQRREKLNPRIAVISGGSREEYSVPVDAIISVQDGDKVKAGDILFKIPTVAEKTRDITGGLPRVDELFEARRPKDATTLAETDGKIEISGEIVKEKRVLYIHPDNPDLEKVKVTIPIGKQIRVRNGDFVKRGDQIDDGNLDPHDILRVKGVTALQVYLVQEVQEVYRLQGVHINDKHIEVVVRQMLRKVLITDSGDTSFVNQQQIDRLVFNEENKRVIAEGGSPAESVPILLGLTKASLNTESFFSAASFQETTKVLTDAAIKGKTDNLMGLKENVIIGHMIPAGTGTKKYKDIAVFKSAYGDLDRPLEEEEEEEIPQAIAEESDAEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: NU4C_MESVI
Sequence: MNNFPWITSIVMLPILAGLLIPFIPDENGKNVRWYALGIGLLDFLLISYIFGYKYNIQDTSLQLIDDYEWISSINFHWRLGIDGLSIPLILLTGFITTLAMLGAWPIQKNAKLFYFLMLAMYSGQLGVFASQDLLLFFLMWELELIPIYILLIIWGGKKRLYAATKFILYTALGSIFILIAAFGMAFYGENMSFDMQILGEKEYPINLEILFYICFLIAYAVKLPAFPVHTWLPDTHGEAHYSTCMLLAGILLKMGGYALIRINMNMLPNAHIYFAPYLAIIGVINIIYAALTSFAQRNIKRKIAYSSISHMGFVLIGISSFTDIGLSGAMLQMVSHGLIGASLFFLAGTTYDRTRTLILEDMGGIAKYMPKIFAMFTTCSLASLALPGMSGFVAELMVFLGFANSNAYSIEFRGIITFLEAIGIIVTPIYLLSMLRQVFYGSENLKLLKVNNLIDASAREIFIISCLLVPVIGIGIYPRILTQIYDLKTNAIIEHLEIIRSNSQIM
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LPXA_AKKM8
Sequence: MPEIHPTAVVHPAAEIADDVKIGPFCVVGEHVKLGPGCVLHSHVVIDGPSSFGSGNEFFPFSVIGLKSQDLKYKGEPTYLEVGDNNVFRENATINRATDIGGATRIGNNNLFLVSCHAGHDCQIGNHVIFSGFATAAGHVTVGDYAILAGCCAVHQFVSIGEHAMVGAMARVSQDVLPYTIVEGHPAVTRSVNSIGMQRRGFSEEDLKAVRMCYKKLFVNKKLTVHEALEELRHSGYAENACLRRIIQFVETSERGFCH
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.