PharMolix/UniProtQA huggingface dataset:
Protein: MEU10_SCHPO
Sequence: MRLSSRFYLFTSFTAWSVVIAGATPAVCGAPEYIIETQNDLDVLSNCQVVNGSIIMNTSSATSLNFNRIETITGDLIIRNNNYLASVALTSISSVGGELRFEKLTRLASVYAPQLANVGQLTMRILPNLQGIRFDKGIKKAHKLTIEDTQLSTLAGISLNTTDTMVIVNNNYLREVDMPYLESVESKFYVSYNAREISVTLPRLKTVGDMTIQRVAHLQLSNLEEVKGFLGFLNSTLQDISCPNITRIGQSLFFIGNQELTSLNFKQLESIGGTFMIANSAALAQIKGYDKLKTVAGSIDFTGNFSSVELPKLRDVKGGLNIQTTSSDFTCPFRQSDGIIKGKSFVCRGSVDNPRQSKESSFDDDDFDELLGNGTIKGSKNSTSPVKQSGAAKVDSRPFRLVTFFLVLVSGFAHLL
What is the function of this protein?
Required for the formation of the mature spore wall, where it is needed to ensure correct localization of 1,3-beta-glucan.
What are the official names of this protein?
Meiotic expression up-regulated protein 10.
What are the subcellular locations of this protein?
Cytoplasm. Secreted, cell wall. Spore wall. Note=And spore wall during sporulation.
Protein: ATP5I_HUMAN
Sequence: MVPPVQVSPLIKLGRYSALFLGVAYGATRYNYLKPRAEEERRIAAEEKKKQDELKRIARELAEDDSILK
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane.
What are the official names of this protein?
ATP synthase subunit e, mitochondrial, ATPase subunit e, ATP synthase membrane subunit e.
What is the protein family that this protein belongs to?
Belongs to the ATPase e subunit family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: ISCS_HAEIE
Sequence: MKLPIYLDYAATCPVDERVAKKMMAFLTIDGTFGNPASRSHKFGWQAEEAVDIARNQIADLIGADSREIVFTSGATESDNLAIKGAAHFYQTKGKHILTCKTEHKAVLDTCRQLEREGFEVTYLSPEADGLIDLEKFKAALRPDTILASIMHANNEIGVLQDIKAIGELCRANKTIFHVDATQSVGKVEINLEELAVDLMSMSSHKLYGPKGVGALYVRRKPRVRLEAIIHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMASEMPRLKALRDRLYNGLKDIEETYVNGSMEHRLDSNLNISFNYVEGESLMMALRDIAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFTLGRYTTEEEIDYTINLMKGAVEKLRALSPLWDMFKEGIDLNTIEWSAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2C01_ORYSJ
Sequence: MAASSTATRLSPPRLHAPTTPSPHLPLRRSRFSPLRAAKLEAVLTIGTHLIPHPRKAETGGEDAFFVNGDDGGVFAVADGVSGWAEKDVNPALFSRELMAHTSTFLKDEEVNHDPQLLLMKAHAATTSVGSATVIIAMLEKTGILKIASVGDCGLKVIRKGQVMFSTCPQEHYFDCPYQLSSEAIGQTYLDALVCTVNLMEGDMIVSGSDGFFDNIFDQEIVSVISESPGVDEAAKALAELARKHSVDVTFDSPYSMEARSRGFDVPSWKKFIGGKLIGGKMDDITVIVAQVKAVMIPDDEGVDEEKGQGDEQGSAVAVASSEQKEDSITT
What are the official names of this protein?
Probable protein phosphatase 2C 1, OsPP2C01.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: TRI13_BOVIN
Sequence: MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGNVRNSLWRSSPFKCPTCRKETSATGVNSLQVNYSLKGIVEKYNKIKVSPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQYTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIIFLQQMQEFREKIKVIKETPLPPSNLPSSPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWRLYPLFVVVILLGLLIFFSPTMFLEWSLFDEIATWKDNLSNFSSYLTRSADFVEQSVFYWEQLTDGLFIFSERLKSFTLVVLNNVAEFVCKYKLL
What is the function of this protein?
Endoplasmic reticulum (ER) membrane anchored E3 ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD).  This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins.  Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation.  Regulates ER stress-induced autophagy, and may act as a tumor suppressor.  Also plays a role in innate immune response by stimulating NF-kappa-B activity in the TLR2 signaling pathway.  Ubiquitinates TRAF6 via the 'Lys-29'-linked polyubiquitination chain resulting in NF-kappa-B activation.  Participates as well in T-cell receptor-mediated NF-kappa-B activation.  In the presence of TNF, modulates the IKK complex by regulating IKBKG/NEMO ubiquitination leading to the repression of NF-kappa-B.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM13, Putative tumor suppressor RFP2, RING-type E3 ubiquitin transferase TRIM13, Ret finger protein 2, Tripartite motif-containing protein 13.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Concentrates and colocalizes with p62/SQSTM1 and ZFYVE1 at the perinuclear endoplasmic reticulum.
Protein: PURP_METBU
Sequence: MISKQQISEIISNYDLNDLAIATVCSHSSLQIFDGARKEGLRTIGICVGQPPRFYDAFPKAKPDEYIVVESYSDIPKIAEELVRKNAIVIPHGSFVEYMGTESFAELAVPTFGNREVLEWESDRDKEREWLEGAGIHMPKIVDPEKIESPVMVKYHGAKGGRGFFIAKDYEEFKQYIDPNEKHTVQEFIVGTRYYLHFFYSPIREEGYKLSEGILEMLSMDRRVESNADEIFRLGSPKELEDAGIHPTYVVTGNVPLVARESLLPRIFALGEKVVEESLGLFGGMIGPFCLETVFTDKLEIKVFEISARIVAGTNLYTSGSPYSDMIEENLSTGKRIAQEIKLGAKTGKLDLILS
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ATPB_STRPS
Sequence: MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIVLEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDLEAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQLGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDEEKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAFRGVGSIEDVIAKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LIP_PSEU0
Sequence: MKKKSLLPLGLAIGLASLAASPLIQASTYTQTKYPIVLAHGMLGFDNILGVDYWFGIPSALRRDGAQVYVTEVSQLDTSEVRGEQLLQQVEEIVALSGQPKVNLIGHSHGGPTIRYVAAVRPDLMPSATSVGAPHKGSDTADFLRQIPPGSAGEAVLSGLVNSLGALISFLSSGSAGTQNSLGSLESLNSEGAARFNAKYPQGIPTSACGEGAYKVNGVSYYSWSGSSPLTNFLDPSDAFLGASSLTFKNGTANDGLVGTCSSHLGMVIRDNYRMNHLDEVNQVFGLTSLFETSPVSVYRQHANRLKNASL
What is the function of this protein?
Catalyzes the hydrolysis of triacylglycerol.  Also able to catalyze, in anhydrous organic solvents, intramolecular transesterification of omega-hydroxyfatty acid esters to form macrocyclic lactones.  This biosynthesis is dependent on the chain length of the substrates, and the formation of monomer lactone is maximum with methyl 18-hydroxyoctadecanoate.  With shorter substrates, monomer lactone decreases and the formation of diolide (dimer lactone) increases.
What are the official names of this protein?
Triacylglycerol lipase, Extracellular lipase, Lactonizing lipase, Lipase P, Triacylglycerol ester hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Pseudomonas lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RM24_HUMAN
Sequence: MRLSALLALASKVTLPPHYRYGMSPPGSVADKRKNPPWIRRRPVVVEPISDEDWYLFCGDTVEILEGKDAGKQGKVVQVIRQRNWVVVGGLNTHYRYIGKTMDYRGTMIPSEAPLLHRQVKLVDPMDRKPTEIEWRFTEAGERVRVSTRSGRIIPKPEFPRADGIVPETWIDGPKDTSVEDALERTYVPCLKTLQEEVMEAMGIKETRKYKKVYWY
What are the official names of this protein?
39S ribosomal protein L24, mitochondrial, L24mt, MRP-L24, Mitochondrial large ribosomal subunit protein uL24m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: 5HT1A_VULVU
Sequence: MEGLSPGQGNNTTSSEGPFGTRGNATGISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKAERKGADARSGVSPAPQPRKSVNGEPGGREWRQGPGSKAGGPLCTNGAVRRGDDGAALEVIEVHRVGSSKEHLPLPSEAGAIPCAPASFEKKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIVRCKFCRRR
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various drugs and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores.  Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism.  Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior.  Plays a role in the response to anxiogenic stimuli (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, Serotonin receptor 1A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: CYMBB_MELOB
Sequence: GKPICGETCAKGKCYTPKCTCNWPICYKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide mobo-B.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family.
Protein: YCEH_ECO45
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVEDQPAVMDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: MPK20_ARATH
Sequence: MQQDNRKKNNLEMEFFSDYGDANRFKVQEVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHPDIVEIKHIMLPPSRREFKDIYVVFELMESDLHQVIKANDDLTREHYQFFLYQLLRALKYIHTANVYHRDLKPKNILANANCKLKICDFGLARVAFNDTPTTIFWTDYVATRWYRAPELCGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTISRVRNEKARRYLTSMRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTAEEALADPYFKGLAKVEREPSCQPITKMEFEFERRKVTKEDIRELISREILEYHPQLLKDHMNGADKASFLYPSAVDQFRRQFAHLEENSGKTGPVAPLERKHASLPRSTVIHSTAVARGGQPKLMNNTNTLNPETTQNIPFNHATIQAQQRNLSAAKPSTFMGPVAPFDNGRISRDAYDPRSFIRSTNLPFSQQSAATVAMGKQQERRTTMEPEKQARQISQYNRYAPDVAINIDNNPFIMARTGMNKAENISDRIIIDTNLLQATAGIGVAAAAAAAAPGGSAHRKVGAVRYGMSKMY
What are the official names of this protein?
Mitogen-activated protein kinase 20, AtMPK20, MAP kinase 20.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: SAT1_BACSU
Sequence: MSLAPHGGTLVNRVDESYDVSGIQKEIELDLISFADLELIGIGAYSPIEGFFNEKDYVSVVENMRLSSGVVWSLPITLPVDAQKAAELSLGETVKLTYEGETYGVIQIEDLYVPDKQKEAVNVYKTDEQEHPGVKKLFSRGNTYVGGPITLIKKASKQFPEFTFEPSETRRQFAEKGWETIVGFQTRNPVHRAHEYIQKTALETVDGLFLNPLVGETKSDDIPADVRMESYQVLLDHYYPKDRVFLGVFLAAMRYAGPREAIFHALVRKNYGCTHFIVGRDHAGVGDYYGTYEAQELFDTFKPEELGITPLKFEHSFFCKKCGNMGTAKTCPHGREHHVILSGTKVRGMLRDGVLPPAEFSRKEVVEVLIKGMKKKEEVGVS
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: DAPF_SALDC
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLSDRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLSVTEDELVRVNMGEPNFEPAQVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDNVDTAAVETLGPVLESHERFPERANIGFMQVVRREHIRLRVYERGAGETRACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAAHIYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAPA_AERHH
Sequence: MKLSRRDFMKANAVAAAAAVAGVSAPTLAANLITSTDKTAITWDKAPCRFCGTGCSVLVGSQDGRVVATQGDPDAPVNRGLNCIKGYFLSKIMYGQDRLTQPMLRMTDGKFDKNGNFAPISWDQAFDIMAEKFKTTLKEKGPTAVGMFGSGQWTVWEGYAAAKLMKAGLRTNNLDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRISDRRLSHQDVQVHVLSTFEHRSFELADNGMVFTPQTDLAILNYIANYIIQNDKVNWEFVNKHTQFRKGVTDIGYGLRPTNPLQQKAKNPDSGDSTPMSFDDFAKFVADYDLESVSKLSGVPKDKLEKLAQLYADPSKKVVSYWTMGFNQHTRGVWANNLCYNIHLLTGKISTPGSGPFSLTGQPSACGTAREVGTFAHRLPADMVVTEPKHRAIAEKIWKLPEGTIPEQVGYHAVLQNRMLKDGKLNAYWVMCNNNMQAGPNMNEEGLPGYRNPANFIVVSDPYPTVTAQAADLILPTAMWVEKEGAYGNAERRTQFWHQQVKPPEGAKSDLWQLMEFSKRFKVEEVWPAELIAKMPEVKGKTLFDVLYANGQVNQFPKEQSKGALNDEAEHFGFYVQKGLFEEYATFGRGHGHDLAPFDQYHEARGLRWPVVDGKETLWRYREGFDPYVKAGEGVRFYGKPDGKAVIFALPYEPAAEAPDKEYDMWLSTGRVLEHWHTGTMTRRVPELYRAFPDAVLFMHPEDAKARGVRRGEEVIVSSRRGEVKTRVETRGRNRPPKGLVFMPFFDASQLVNKLTLDATDPLSKETDYKKCAVKVVKA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSTB_CLOPS
Sequence: MSDKKTKIQVRDLDLFYASNHALKKINIDIKENEVTALIGPSGCGKSTFLRTLNRMNDLIPIVRIEGEIQVDGKDIYKDDDVIALRTKVGMVFQKPNLFPMSIYDNVAYGPRVHGIKDKKVLDKIVEESLRDAAIWDEVKNRLKSSALGLSGGQQQRICIARAIAMNPEIILMDEPTSALDPISTLKVEELIRKLEDKYTIVIVTHNMQQAARISDKTAFFLNGELVEFSDTNTIFTNPRDKRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RFBE_YEREN
Sequence: MTSLIFKNVTMSYPIYNAHSQSLRNQLVRVSTGGRIGGSRGEVVTVTALDNISFELNSGDSVGLIGHNGAGKSTLLRTMAGIYPASSGEIIREGSVATVFELGAGMDPELSGYENIMRMLLLLGNSVASAKSKIPEIEEFCELGDFLVLPVRTYSSGMTMRLMFAVATSMRPEILLIDEMFGTGDAAFQEKAEKRMRDWIAGSDIFVFASHDRSLIKKLCNRIFRLEHGLIYEESMDIL
What is the function of this protein?
May form an ATP-driven O-antigen export apparatus, in association with RfbD.
What are the official names of this protein?
O-antigen export system ATP-binding protein RfbE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SECA_MYCMS
Sequence: MVSDRRLLKKFGKIADKIIALEPQMRQLKDEDFILKTQEFKQMLENGKSLDDILIEVYAVAREAARRVLGLNAYKMQLIGGIILNSGDIAEMRTGEGKTLTGIFPAYLNALSGKGVHIVTVNEYLSRRDSEINGKVFDLLGISVGLNGSSLTKTEKREAYNKDITYTTNAELGFDYLRDNMVSDYSLKVQRKLNYCIIDEADSVLIDEARTPLIISGGTSTRINLYKAANNFALTLKEHDDLDIDLESKQVYLNEQGMKKANEFFSLKNLFAIENTEIFHLIMNALKAQFAFKEGVEYTVRDNEILLIDQFTGRIMHGRSYSDGLQQALQAKENVDIEEETVTLATITYQNFYRLYSKIAGMTGTAKTEEEEFIKIYNTRVIQTPTNKPVIRKDEPDLTFGTKNAALKKLVEDVLEAHKKGAPILIGTTSVESSEQIARYLKKANLKFETINAKNHDREAEIVAKAGEIGAITLATNMAGRGTDIKLAKGVAELGGLRVFGVERNEARRIDNQLRGRSGRQGDPGLSRFYISMDDDLMMRFTAPKTRQRFKALGDDYIKSKMFTRAVTNAQKKLEGMNFDQRKNVLDYDNILAQQREIIYAQRDDILEANDLSVVIEKMQITAAYELIEKHSTLVHGEKTINKKELLEVIDGILVPKNKFRIDDFNNKEKMDLAVEIAEAMMQLYKARISDIPDDVIIVMERKIILDAFDKHWTKHLDIAGKLKSGIYLQQYAQNNPLAIYIEQATNLFNKMKINIANEVVENLANVILRVVEDEEQREERIEVTDKDIEEILFETGLQPSDINNKAINQRFDELEEEFKDDKQKLRRLRIQRDVMLGLVLELERRAEMIISPQNDQQAITQLIKELQNDIDIASITIDQIHQNFNNMVEQINDPEKLKHLVIAKDVLLQLVARMDDIKEQEKQTRKKKKKKPHEDESSKTKIG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: Y583_TREPA
Sequence: MRSSIAPTAPAACSSKRWYPSVCEPDVRNQKNWGHPITPCA
What are the official names of this protein?
Uncharacterized protein TP_0583.
Protein: FRBA_BLOB1
Sequence: MSIPSLDYRLFSHGDPAQRQQFCEDLVKTFAGYGFAKLRNHGLSDERVDEAFSYSNKFFNLPLHIKQKAKHPEAPNPHRGYSGVGQEKISAITGFEKGERSEVRAAELRESWDQGPADDELYANRWMPDEDLPGYRSFMESFFVECQTLHQSLLQCIATGLSLPSDELSSRCAKCSAELRLNHYPATPASSLASGACRISPHSDFGTITLLFQDSVGGLQVEDQQNPGVFLPVEPDDVHEMIINVGDCLSRWTDGRLRSVNHRVVSPTRLPGDADVMIPERHSLAYFGKPSRDEVVDSLPLFVPEGCKPKFADRWTALEYNQSKLMRTYNVETAAQG
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of the antifungal antibiotic FR901469, an inhibitor of beta-1,3-glucansynthase, exerting antifungal activity against the pathogenes Candida albicans and Aspergillus fumigatus (PubMed:27660098).  FR901469 is a cyclic depsipeptide containing 12 amino acid residues and a fatty acid chain (PubMed:27660098).  The NRPS frbI contains 12 modules responsible for the formation of the depsipeptide backbone which is denoted as Acyl-Thr-Ala-Tyr-Val-4OHPro-Thr-Thr-3OHPro-threo3OHGln-Gly-Thr-Orn-OH (C71H116N14O23) (Probable).  The PKS frbB is probably involved in the production of the hydrocarbon chain, and the acyl-CoA ligase frbC might be involved in the transport of the chain to the peptide ptoduct of frbI (Probable).  Because FR901469 contains 3 hydroxylated amino acid residues, the 3 oxygenases frbA, frbH, and frbJ might be participating in amino acid hydroxylation (Probable).  As no thioesterase domains were detected in frbI or frbB, the thioesterases frbD and frbE may instead release and cyclize the products of the NRPS and PKS, respectively (Probable).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase frbA, FR901469 biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: FLHC_VARPS
Sequence: MTRKSVLGEVREVQLAIQLIQLGARLQFLESEVGLSRERLIRLYKEIKGVSPPKGLLPFSTDWYMTWLANIHSSMFYNMYQFMKIHSDEEKVWILIKSYKLYLQQIAAQDSEPILDFTRAYTMVRFFDSDMLQLSTCCRCSGQFVAHAHDHKSGYVCVLCRPPSRAGKARGAKRGAEGEAGALGIEGMGFGVEAAPGGAGFH
What is the function of this protein?
Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhC.
What is the protein family that this protein belongs to?
Belongs to the FlhC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRD7_CAEEL
Sequence: MFDISFLFIGINSILTLLGCFINLFLCYLAIFQSPKAIRTYSLVLINITLTNVGACVTGFLLDQRIIQSGKSMLYVSYGYCSLLGEGFCFNIFAAYLHFHTHALWLLFLSFVYRYYVIIRQEPTKKVLQISVVIVYIPSLIQLISMCLQEMNFDELRSLSKEVVPQYNLTGLTITGSLDFFTFAPFYCLVHMAIISFLIAIGIHILRKMIINRMVLNGVDVTIRSRNLHAQLLRTLSFKATVPIIYYFGCIFFILGRIWINPIFEFSIFVPTVIVPVLTPLSAFIHVAPYRDFVSKMFHGRPKNKTVNSICIIPIISH
What are the official names of this protein?
Serpentine receptor class delta-7, Protein srd-7.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srd family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: THII_SHEAM
Sequence: MKFIVKLYPEIMIKSKPVRMRFTKMLESNIRNVLKKIDEDAKVQRQWDKIMVKVPKDKPELTELFAERLAHIPGIHHVLQVAEYDFETVDDIYQLALPVYRDMLKDKTFCVRVKRAGQHDFNSIEVERYVGGGLNQFTEAKGVQLKNPDVTIQLEIDRDKLYMVSQRIEGLGGFPIAAQEDVLSLISGGFDSGVASFQFIKKGSRTHYCFFNLGGAQHEIGVKQVAYHLWKTYGESHKVKFVSVPFEEVVTEILERIENGQMGVVLKRMMMRAATRVAERMGIQALVTGESLGQVSSQTLTNLNVIDRSTDLLILRPLISMDKPDIIREARRIGTEDFAASMPEYCGVISQRPTVKAVLSKVEAEEQKFSEDLLDRVLAKAEVIDIRDIAVATSERVTETETVSSAAGNEVIIDIRAPEEEESRPLDVDGVEVKVIPFFKLATAFAELDKDKTYLLYCERGVMSKLQALYLQEQGYNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD32_ARATH
Sequence: MALEKEEEASQNGAFCVLDGLYCEEETGFVEDDLDDDGDLDFLEKSDESVVKFQFLPLLDMFLWDDDEILSLISKENETNPCFGEQILDGFLVSCRKEALDWVLRVKSHYGFTSLTAILAVNYFDRFMTSIKLQTDKPWMSQLVAVASLSLAAKVEEIQVPLLLDLQVEEARYLFEAKTIQRMELLILSTLQWRMHPVTPISFFDHIIRRFGSKWHQQLDFCRKCERLLISVIADTRFMRYFPSVLATAIMILVFEELKPCDEVEYQSQITTLLKVNQEKVNECYELLLEHNPSKKRMMNLVDQDSPSGVLDFDDSSNSSWNVSTTASVSSSSSSPEPLLKRRRVQEQQMRLPSINRMFLDVLSSPR
What is the function of this protein?
Promotes divisions in the guard cells (GCs) after the guard mother cells (GMC) symmetric division when in the presence of CDKA-1.
What are the official names of this protein?
Cyclin-D3-2, G1/S-specific cyclin-D3-2, CycD3;2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.