PharMolix/UniProtQA huggingface dataset:
Protein: SPRC_XENLA
Sequence: MRVWVFFVLCLAGKALAAPQQDALPEEEEVIEDVPAEETVGTNPVQVDVGEFDEAINEEEEEEPSENPCLNHHCKHGKVCEVDESNTPLCVCQDPSTCPTSVGEFEKICGTDNKTYDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIAPCLDNELSEFPLRIGDWLKNVLVSLYERDENNNLLNEKQKLRVKKIHENEKRLESWRPHSELLVRDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELSPLRAPLIPMEHCTTRFFDECDIDDDKYIALEEWAKCFGIKEQDVDKDMIV
What is the function of this protein?
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines.  Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes.  There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity).
What are the official names of this protein?
SPARC, Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine.
What is the protein family that this protein belongs to?
Belongs to the SPARC family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.
Protein: ATPB_RICTY
Sequence: MTQNIGKITQVISAVVDVKFTNNSKLPEILNALECYNAKQRIVLEVAQHIGDDTVRCISMGSTEGLIRGLEVIDTGNPIHIPVGIATLGRIMNVVGEPIDGKGEIKSSTISSIYKPAPDFINQSTERDILVTGIKVVDLLAPYTKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYTVFAGVGERTREGNDLYHEMIASGVINLEAPEKSKVALVYGQMNEPPGARARVALSGLTIAESFRDMNAGQDVLFFVDNIFRFTQAGAEVSALLGRIPSAVGYQPTLATDMGELQERITSTKHGSITSVQAIYVPADDLTDPAPSTSFAHLDATTVLSRQIAELGIYPAVDPLDSNSQVLDPMIVGEEHYSVARQVQQVLQTYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFHVAEVFTGVEGKFVNLDDTIAGFKGLVEGKYDDLPEAAFYMVGTIDEAVEKAKILKI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DUS3_YEAS7
Sequence: MEQNAEKRSIVGDDNSTVKRQDTSPSKGIAHIKPEYIVPLKQNENQKVAIYDEEMSSDRMTNEFAGGTNKKNKNGRGKKRGQNKNRDNRQVKEQNVLCPRLIHGDISKCSFGDNCRFVHDINLYLSTKKPEVESNIFPSCPVFNSLGFCPMGFKCRFLSSHLNKEDNILISKKEIDPDAQTIWSVKGEVNHISPERKLDLIKRRFPFTKSNEILEIIDSFQQECRDSMKPEEEVESTPQLKKQDPDVEQPVAPQVEQRNKELSEHRMKQREVYLKYKDTRYFAQEKKPLDLYHKKIVSPLTTVGNLPYRRLMRKLGADVTYSEMALAVPLIQGTNSEWALPKAHTSEFPGFGVQVACSKAWQAAKAAEALANSVSEISEINLNSGCPIDLLYRQGSGSALLDNPARMIRCLNAMNYVSKDIPITVKIRTGTKEGHPIAEGLVKRLVNETDVAAITLHGRSRQQRYTKSADWDYVSQVADTLRSAEADFIETEQGKEGRDSKNRIQFVGNGDVNNFEDWYRYLNGNENIDSVMVARGALIKPWIFEEVESQQYLDKTSTERLDILRDYAQFSMEHWGTDEYGISQCRRFFCEFMSFFHRYVPMGICERYPVKLNERPPNWCGRDELETLMGSTDVNDWIKLSDLFFGKTDENFVFVPKHKSSSYANRDS
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SPRTL_BACCQ
Sequence: MDEQEIQRLVEEVSLQYFGMPFLHKAMFNSRLRTTGGRYLLNTHNIELNYRYYEMYGKEELVGIVKHELCHYHLHIAGRGYKHRDKDFRELLKAVDAPRFCKRMINEEKGKKVYMYECMECSLQYVRRRQINTKRYVCGKCKGKLILIKKTS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAH_SALEP
Sequence: MTWFIDRRLNGKNKSTVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTDDISEPMFHQGRGGLRHRVHPGNDHFIQNDRIERPQGGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKKNQHRQLNEYKTHRAGFTSNGVPANISVVRSLQNSLARRTAMTAGKRRELHALETELETISHSEPAQLLEEERLRREIAELRAKIERVPFIDTFDLRYKNYEKRPEPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYDPGQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQATFDNFAMQHIRDQEDIYPVFRELFQKQSANQSV
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: PEPQ_AERHH
Sequence: MSSYSQLFAQHLDTLQQRTRDILQQQGLSGLAIHSGQTHRIFLDDQDYPFKVNPQFKAWLPVLDNPHCWLLVDGVNKPVLLFYRPVDFWHKVAELPNAFWVDFFDIRFLTRPEQVADHLPANKQEWAYLGGHLEVAELLGLGQPNPEAVLNYLHYHRAYKTAYELECLRDANRIGVRGHIAAKDSFMAGASEFEINLAYMKAVGQGANEAPYGNIVAINRNAAILHYTHLSAQRVPDAERYSFLIDAGVDVHGYASDITRTWAWRRGEFADLIAALDAQQQEIIEEIKPGRRYSELHLQMHHRLARLLQATELVDMSVDEMIHTGVTNVFFPHGLGHFLGLQVHDAGGFMQDERGTHLSAPEQFPYLRCTRVMEVGQVFTIEPGLYFIDSLLEPLRLGEQGKRVNWNKVEALRPYGGIRIEDNVVLHANGVENLTRQAGL
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: PIMT_METMA
Sequence: MPERRGIVLVNAVSEKDLGEDKRKREKEKECEKLRKLLVEGLEGFVIDEKVLQAMLRVPRHRFVPEYEQRAAYVDMPLEIGHGQTISAPHMVAMMCEILELAEGHKVLEIGAGSGYNAAVMSELVGKTGHIYTVERVEPLANFAKKNLKEAGYKNVTVLLENGSMGYPGYAPYDRIAVTCAAPNIPETLLEQLKPGGIMVIPVGSYSQELIRVKKDSTGKIYRKKKGDVIFVPMIGKHGFRRI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_SHISS
Sequence: MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEYLEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLNMVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: YLCI_ECOLI
Sequence: MSTKNRTRRTTTRNIRFPNQMIEQINIALEQKGSGNFSAWVIEACRRRLTSEKRAYTSIKSDEE
What are the official names of this protein?
Uncharacterized protein YlcI.
Protein: FRHD_METTH
Sequence: MPYDAEILVVGCGNILFKDDGFGPEVIKALEEYFKDREKPDNVMFIDAGTGGPHFVFSLPHEEWKKMIVVDVVEFNAEPGTLRKFDVTEIPKGSYENMHTWPVSQPLHELSEKIDVVVIGCKPKEISAPNVEMGLTPPVKKAIPRAIQMILDEIGVSK
What are the official names of this protein?
Coenzyme F420 hydrogenase subunit delta, Putative coenzyme F420 hydrogenase-processing subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase A31 family.
Protein: UPPS_METAC
Sequence: MKNRTFSMFYQEYEQLLEKEILSSEIPDHIAVIMDGNRRYAGQRGRTRSFGHAMGAEVTEQVIEWCYEIGVKELTLYAFSTENFQRSEEEVDGLFNLINEKFLKLYNDKRTYEKETQIRVIGDRTKLPAFLNKSIEKIEKATETHRKFNLNVAIAYGGRQDIMQAVRDIAACVSSGKLSLEDVDENLISKHLYPAPGVSVPNVDLIVRTGGDERVSNFLPWQANGSECATYFCAPFWPEFRKIDLLRSIRVYQARKDEKKQENSYRVSKVINFLGVGKYGEKSEELGQLLPLKKQGVA
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP).  It is probably the precursor of glycosyl carrier lipids.
What are the official names of this protein?
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific), Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: SAPE_SARPE
Sequence: MKSFIVLAVTLCLAAFFMGQSVASPAAAAEESKFVDGLHALKTIEPELHGRYKRATCDLLSGTGINHSACAAHCLLRGNRGGYCNGKAVCVCRN
What is the function of this protein?
Sapecins, which are potent bactericidal proteins, are produced in response to injury.  Sapecin is cytotoxic to Gram-positive bacteria, and to a lesser extent against Gram-negative bacteria.
What are the official names of this protein?
Sapecin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCNK_MOUSE
Sequence: MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQGPQSQPSQGSEAAQPPQKDSQQSAQQQQQQAQQPKKPSPQPSPPRQAKRAVVVSPKEENKATEPPPPPKIPKLEATHPPLPPAHPPPDRKPPLAPALGEAEATGPVETSDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPASFPPPTIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR
What is the function of this protein?
Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases.  Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).
What are the official names of this protein?
Cyclin-K.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYL_PSEE4
Sequence: MHEQYTPRDVEAAAQNAWDEQQSFAVTEQPGKETYYCLSMFPYPSGKLHMGHVRNYTIGDVIARYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPADQTVLANEQVIDGRGWRSGALIEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIGHEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNAALQAFIDECKSGSVAEADMATQEKKGMATSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNLPVKAVVRTSAGDDVGSEWLAAYGEHGQLINSGEFDGLDFQGAFDAIEAALIRKDLGKSRTQFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLPENVVPDGAGSPLARMPEFYECTCPKCGTAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNPADVEIERDAKAKIIGARLKTDGLPVEIGGTEKMSKSKNNGVDPQSMIEQYGADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQAHVAQGLPGQLDIAALSDEQKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQVTAQDRALLQEGLEAVTLLLAPITPHISHELWKQLGHEQAVIDATWPSVDESALVQDTVTLVVQVNGKLRGQVEMPAAASREEIEAAARNNENVLRFTDGLTIRKVIVVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_EDWI9
Sequence: MNPIVINRLQRKLGYTFRQHDLLMQALTHRSASSKHNERLEFLGDSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAEMAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGIFLDSDIQTIERLILDWYRSRLEEISPGDKQKDPKTRLQEFLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSAPVVGVGSSRRKAEQAAAEQALKQLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STCF_EMENI
Sequence: MILPLILVLYLLSTAAYRLWLHPLRNYPGPCWWAVWRVPYLKGTIRGTIVRDIQRLHNQYGPVVRIAPDELSYITPEAAKPIYTSSPEFPKDPMHLPPFHNGAPGILAADYAHHRRYRRLLASAFSEKGLRAQQGMIQSHIDRLMTRLQGNCSSGSLDMTVWFNWATFDIIGDLAFGEPFGCLERMETNPWIASIQGNVKSIPILNALRRYRLDRLIEFLAPPRLLEMRRRNAQFTAEKVDRRLKHATTTRGDLWDSVLADPPDGEPPMSRAEMVSNASAIVLAGSETSATTLSGCLWLLLTNPEYLQQLTERIRARFSTATVIDAQTVTQIQGLQAVLDESLRLYPAVPMQSNRIVPPPGARLAGSWVPGGTSVAVQQFAACRSPTNFHRPDEFIPERWEKEGEFINDRREASQPFSIGPRNCIGRQLALAEMRLILVHLLWHFDIELDRRRMENMDWMAVQGIWILWDKKPLWVVLKNRST
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of sterigmatocystin (ST), a polyketide-derived furanocoumarin which is part of the most toxic and carcinogenic compounds among the known mycotoxins (PubMed:8643646, PubMed:10618248).  The first step in the biosynthesis of sterigmatocystin is the production of hexanoate by the fatty acid synthase (FAS) units stcJ and stcK (PubMed:8962148).  The polyketide backbone is assembled by the non-reducing polyketide synthase stcA by condensation of the starter hexanoyl-CoA and 7 malonyl-CoA extender units followed by cyclization and release of norsolorinic acid (By similarity).  Norsolorinic acid is the first stable intermediate in the biosynthesis of sterigmatocystin and is converted into averantin (AVN) by the ketoreductase stcE which reduces the hexanoate ketone to an alcohol (PubMed:8643646) (Probable).  Averantin is then oxidized into 5'-hydroxyaverantin (HAVN) by the cytochrome P450 monooxygenase stcF (PubMed:10618248).  5'-hydroxyaverantin is further converted to 5'-oxyaverantin (OAVN) by the 5'-hydroxyaverantin dehydrogenase stcG (PubMed:24957370).  The next step is the conversion of OAVN into averufin (AVF) which is catalyzed by a yet to be identified enzyme (PubMed:24957370).  The cytochrome P450 monoxygenase stcB and the flavin-binding monooxygenase stcW are both required for the conversion of averufin to 1-hydroxyversicolorone (PubMed:10618248).  The esterase stcI probably catalyzes the formation of versiconal hemiacetal acetate from 1-hydroxyversicolorone (PubMed:24957370).  The oxydoreductase stcN then probably catalyzes the biosynthetic step from versiconal to versicolorin B (VERB) (PubMed:24957370).  The next step is performed by the versicolorin B desaturase stcL to produce versicolorin A (VERA) (PubMed:8999832).  The ketoreductase stcU and the cytochrome P450 monooxygenase stcS are involved in the conversion of versicolorin A to demethylsterigmatocystin (PubMed:7486998).  The Baeyer-Villiger oxidas stcQ and the reductase stcR might be involved in the biosynthetic step from versicolorin A to demethylsterigmatocystin (PubMed:24957370).  The final step in the biosynthesis of sterigmatocystin is the methylation of demethylsterigmatocystin catalyzed by the methyltransferase stcP (PubMed:8900026).
What are the official names of this protein?
Cytochrome P450 monooxygenase stcF, Cytochrome P450 60A2, Sterigmatocystin biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: MECP2_MACFA
Sequence: MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEDKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS
What is the function of this protein?
Chromosomal protein that binds to methylated DNA.  It can bind specifically to a single methyl-CpG pair.  It is not influenced by sequences flanking the methyl-CpGs.  Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A.  Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
What are the official names of this protein?
Methyl-CpG-binding protein 2, MeCp-2 protein, MeCp2.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalized with methyl-CpG in the genome. Colocalized with TBL1X to the heterochromatin foci.
Protein: Y1006_EMENI
Sequence: MPESPFLLLPPELRLQIYSYVLDIPTPYTTLTQHSKPLIVINDTGNKYTTRAIYRSLHISPNWVGISKSEGPNERSKTLSLLSVNRQIHAEVEHFLYTSHTLFFLNGFDLDHLGEFLDTLSATARSCIRSIGFEVYLFVHNTPGPVKRGFRQYERAARVVREKLPNLRGVVFYFDPWFLACCGDAGFGPWCDERSVLATGVRYLLKVFGGIEPRDKDNDKLRARVEMDLHFLPSSATFKVPGLEQGHAKSLVKVS
What are the official names of this protein?
Uncharacterized protein AN11006.
Protein: CYB_BOTAT
Sequence: YINYKNMSHQHLLTLFNLLPVGSNISTWWNFGSMLLACLMIQIITGFFLAIHYTANINLAFSSIIHLSRDVPYGWIMQNTHAISASLFFICIYIHIARGFYYGSYLNKEVWLSGTTLLIILMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTLTTWLWGGFAINDPTLTRFFALHFILPFIIISMSSIHILLLHNEGSNNPLGTNSDID
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TIFA_XENLA
Sequence: MDKELIDVDTEQTISCLTLTLYHPNHQDQKLFRGINFSRKEEIKADAVVAFGRDYNVCRYPLLSNRVSRIQFNLQLFKHFNCSTSTFEIKNLSKKNKLYVDNLELDYLNKIELPKKCMIRFGDFQILAEIDEGDSDEKFEICCEKSHVSLVQDSFIPTMQPIPECGTLNAVEIDENEC
What is the function of this protein?
Adapter molecule that plays a key role in the activation of pro-inflammatory NF-kappa-B signaling following detection of bacterial pathogen-associated molecular pattern metabolites (PAMPs) (By similarity).  Promotes activation of an innate immune response by inducing the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (PubMed:16023795).
What are the official names of this protein?
TRAF-interacting protein with FHA domain-containing protein A.
What is the protein family that this protein belongs to?
Belongs to the TIFA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPA_BORAV
Sequence: MNKPSKFALALAFAAVTASGVASAQTVDNWRNPYGNVWKNGTNELCWRDAFWTPATGIPGCDGVPVAQQPKEKPAPMAAKVVFNADTFFDFDKSTLKPEGRQLLDQVAQQARAIDLETIIAVGNTDSIGTEAYNMKLSERRAASVKAYLVSKGIDPNRIYTEGKGKLNPIASNKTAEGRARNRRVEIEIVGSRK
What is the function of this protein?
Structural protein that may protect the integrity of the bacterium.
What are the official names of this protein?
Outer membrane protein A.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: MATRX_RABVI
Sequence: MNFLRKIVKNCRDEDTQKPSLVSAPPDDDDLWLPPPEYVPLKELTGKKNMRNFCINGEVKVCSPNGYSFRILRHILRSFDEIYSGNHRMIGLVKVVIGLALSGAPVPEGMNWVYKLRRTLIFQWADSRGPLEGEELEYSQEITWDDDTEFIGLQIRVSARQCHIQGRIWRINMNSRACQLWSDMSLQTQRSEEDKDSSLLLE
What is the function of this protein?
Plays a major role in assembly, budding and uncoating of virion after membrane fusion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication.  Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons.
What are the official names of this protein?
Matrix protein, Phosphoprotein M2.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus matrix protein family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein. Host cytoplasm.
Protein: VF022_IIV6
Sequence: MEFKLEDFFPLYPESLSNNSKTRFEIGSLDVINTLKEFTDNRLDAIEILPTKPGEATKHQIVIRRLLSGYTQFDALLLVHEMGTGKTCSAIQAIEQNLIESNNGLFLRTVQTTEGIDDFNFNKNCNNNYGPGLDGAVILTRGKTLMNNFMDELVNRCSTNYSSGNRNEISKTSKKLFSKFYSFYTFEIFAKTVKKMRSSEIVKKFDNKIIVIDEAHNLRLSDVKVNDEKIDVYGEVHRFIHLLTNKKVLLLTGTPMKDGPQEIASLMNLILPLTQQMPTNKNFLKEYFPSTEAPQETYELGDEEEFLKSGGEEMKNIKKFKAQVYGCVSFLKAMDSKVLKVMVGERMGSLKHYKVVPEYMSTFQSKAYVSAYLQDKRERGIYNNSRQASRFVFPDGTYGAEGFKNYIIEKRGRGGKIFRLSPSLRKEIEKRSSFKSVHTLTDEQKEFLYLQNINEYSAEYAYIIKSILNATRNGELSIVYNDSVRGSGLIVLTLLLELFGFVRNNGTAKMKKSYGIFSNETTSVREIRALQKIFNSDENMNGNIMPVIFGSRVIAEGLTFKNVIHEHVVPHWNGSETEQVIARGWRLGSHEALIKKWEQNGQVGKKPQLNVYRHVVIPSSLLSSEVSRREDDLSLVTSSSRGIMENREIKSIDLIMYEVSEKKDIAISKVLRCLKEVAIDCQLFKKRNEKDSSFDYKRECEYEKCLYVCDDNGNNLTKKNIVNYETIYFREDVFLMFAMLENHYKTRFVSTLDEITEMFFNNKVLTHSVTKQEIIQLLYQVVSNNIPIKNVYGYPCYLYENYNVYYLVDHIIPFPSSEDIFLAYYSKHPQLYVKTDSQESGKASGTNYYQSVTWFNNVLNDYYESLIPLAIKDLTTLSNSTNLVSKTQMISKQLISLPNDVQQRIIEMAVAARVLEIYCNVQNTLPPLPAQLSKEWIERNQKSVFCKKKTFRTIILDHYKNYYRIDGVDSFKMAIVWFLSDIVEERAKERCLYGSSLNLKSGYTARPLWNEWKICGKKERVRVEKERSLIKKQYETDLGYYGLWNPKNNEFCIRDIRNQTGKKDKRSIPSGKRCVNWTKPALTELAAIAINIPIPNQSVLPTLKEAMEEIKSNKELRNIVPKDNNDNNLLIKLVFWYKLSRNDICINLREWFDRNNLLVEDNSCGVQTKRK
What are the official names of this protein?
Putative helicase 022L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 022L family. SNF2/RAD54 helicase subfamily.
Protein: MGRA_STAAS
Sequence: MSDQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVLTILWDESPVNVKKVVTELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKSETIRPELSNASDKVASASSLSQDEVKELNRLLGKVIHAFDETKEK
What is the function of this protein?
Regulatory protein involved in autolytic activity, multidrug resistance and virulence.
What are the official names of this protein?
HTH-type transcriptional regulator MgrA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_STRPZ
Sequence: MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVFLARRIQERLHQLEGLDLPIGELDPKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYTGRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVEVDGRDRVSIIDPT
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: CC42L_XENLA
Sequence: MDQAEYFHSWCRQDEMMLNLLEKCPTQQIQRLPLPIRRLEKKQEIQKMLEARREDYHKAMEGVAREWEKLQEKEAEIRVGLEKYKKSIVKNDKKQERAFRDAAKARSMCIQYDLQLKALQEQCEELDKKRAKTKAQVQKYEKCHRYLEKVVKASEKFQSIPELMSQFHALVSYLPQEEQEEQKSQESRSQRIHCMEEKSDSIVQFSNEIHRLYIRLEKAKKKRREWELRWNQMLKTATRKNLLLGTIKAAVRDIFQTVISQGLGSNSVGEDDIVEQLEIIRKDIEDLTDIWEKLSLNEELMEPIRAPLLPTDKTLGHPPSQ
What are the official names of this protein?
Coiled-coil domain-containing protein 42-like 1.
What is the protein family that this protein belongs to?
Belongs to the CFAP73 family.
Protein: DEFB1_NOMCO
Sequence: MRTSYLLLFTLCLLLSEMASGDNFLTGLGHRSDHYNCVRSGGQCLYSACPIYTKIQGTCYQGKAKCCK
What is the function of this protein?
Has bactericidal activity.  May act as a ligand for C-C chemokine receptor CCR6.  Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner.  Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
What are the official names of this protein?
Beta-defensin 1, BD-1, Defensin, beta 1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: IOVO_AFRCO
Sequence: LAAVSVDCSEYPKPACTMEQRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.