PharMolix/UniProtQA huggingface dataset:
Protein: IF1_ACICJ
Sequence: MSKEDMIEFSGTVAELLPNAMFRVKLDNDHIILAHTSGKMRKNRIRVLAGDRVNVEMTPYDLTKGRITFRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_MLVF5
Sequence: MACSTLPKSPKDKIDPRDLLIPLILFLSLKGARSAAPGSSPHQVYNITWEVTNGDRETVWAISGNHPLWTWWPVLTPDLCMLALSGPPHWGLEYQAPYSSPPGPPCCSGSSGSSAGCSRDCDEPLTSLTPRCNTAWNRLKLDQVTHKSSEGFYVCPGSHRPREAKSCGGPDSFYCASWGCETTGRVYWKPSSSWDYITVDNNLTTSQAVQVCKDNKWCNPLAIQFTNAGKQVTSWTTGHYWGLRLYVSGRDPGLTFGIRLRYQNLGPRVPIGPNPVLADQLSLPRPNPLPKPAKSPPASNSTPTLISPSPTPTQPPPAGTGDRLLNLVQGAYQALNLTNPDKTQECWLCLVSGPPYYEGVAVLGTYSNHTSAPANCSVASQHKLTLSEVTGRGLCIGTVPKTHQALCNTTLKIDKGSYYLVAPTGTTWACNTGLTPCLSATVLNRTTDYCVLVELWPRVTYHPPSYVYSQFEKSYRHKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATQQFQQLHAAVQDDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHTGLVRDSMAKLRERLTQRQKLFESSQGWFEGLFNRSPWFTTLISTIMGPLIILLLILLFGPCILNRLVQFVKDRISVVQALVLTQQYHQLKPLEYEP
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: ARL5_DICDI
Sequence: MGSSLSIFASIWNRFFNNAEYKVIIVGLNAAGKTTTLYKLLLDEVVSTTPTVGSNLEEFVYRNIRLLMWDLGGQDLLRSTWNQYYINTQAVILVIDSTDRARVNLIKEELFKMLAHENLKKSIILIYANKQDLKDAMSPTELSTLLSLHSIKDHDYHIQACCALTGQGLESGLDWLVSHINKS
What is the function of this protein?
May bind and exchange GTP and GDP.
What are the official names of this protein?
ADP-ribosylation factor-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
Protein: HSLV_LEPBA
Sequence: METIHATTILSVRKNGKIAVGGDGQVSMGNTVMKHTAKKVRRLYNGKVIAGFAGSAADAFTLFELFEKKLIEHGGSVSRAAVELAREWRMDRMLRRLEALLIVCDANESFLISGTGDVISPDDGVLAIGSGGNFALSAARALVENTDLDPKEIITKAMNITADICIYTNHNLVIEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_AZOC5
Sequence: MARKYFGTDGVRGRANATLTADLALRVGMAAGLAFRRGEHRHRVVIGKDTRLSGYMIENALVAGFTSVGMDVLLLGPMPTPAVGMLTRSMRADLGVMISASHNPFDDNGIKLFGPDGFKLSDQIEHEIEELIDEDLSKKLAQPMDIGRARRVEGVHARYIEYAKRTLPRDQSFEGLRVVVDCANGAAYRVAPDALWELGAEVISMGVEPDGLNINRDVGSTSPAALSAKVREVRADVGIALDGDADRVIIVDEKGHVVDGDQIMAVVAHSFKEDGRLSRDGIVATVMSNLGLERYLKDEGLTLARTSVGDRYVLERMRSDGYNVGGEQSGHIILSDYSTTGDGLLAALQVLAVVARSERPVSEVCHRFDPLPQVLKNVRYSSGKPLEHENVQSAIADAERRLANHGRLLIRPSGTEPVIRVMGEGDDFELVEGVVDEVIEALRKVAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CCME_ALKEH
Sequence: MKPRHRRLTLIALVLGGLGLSAGLALTAFQDNLVFFFTPSEVMAREAPIDRPIRIGGLVKAGSVEREAASARVHFKVTDTAESITVSYDGILPDLFREGQGVVAQGRLGADGRFHATQVLARHDETYMPAEAKEALDRIGQGNGTPGPDGHPETTTAY
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SYF2_DANRE
Sequence: MASSEEVVAPSNEEEVTETPAAQKREERLRKFRELHFKRNEARKLNHQEVVEEDKRLKLPSNWEAKKARLEYELLVDQKKKECAERGEDYDRVKLLEISAEDAERWERKKKKRNPDPGFSGYAEAQLRQYQRLTKQIKPDMENYEKQKEECGEDFHPTSNSLIYGTHVPSKDSINRMVDDVEKQIEKRAKYSRRRAYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor syf2.
What is the protein family that this protein belongs to?
Belongs to the SYF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASSY_DEIDV
Sequence: MAKDKIVLAYSGGLDTSIILKWLQTERNYDVVCFTADLGQGDEVEEARVKALNTGAVAAYALDLREEFVRDYVFPMFRSSALYEGYYLLGTSIARPLIAKKMVEIAQKEGAVAVSHGATGKGNDQVRFEMTAYALQPDIVTVAPWRDWEFQGRADLEAFAHEHGIPVPTTKKDPWSTDANMLHISYEGGILEDPWAEPPAHMFKLTVAPEEAPDEAEYVEIEFLNGDAVAINGETLSPAALLDRANEIGGRHGVGRVDLVENRFVGMKSRGVYETPGGTLLYHARRAVESLTLDREVLHQRDALGPKYAELVYNGFWFAPEREALQVYMDHVAKAVTGTARLKLYKGNCIVAGRKAERSLYDKDLVSFEAGGDYNQHDAGAFIKLNALRMRVQARVEAKAGQKDKAGD
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_BDEBA
Sequence: MAVVIRLARMGAKHEPKYRVTVADSRRYVTGKFLDILGTYIPSPKGNDKKIELDLAKVEEWIKKGAQPTDRVKHVIKLAQAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RS3_ZYMMO
Sequence: MGHKSNPIGMRLQINRTWDSRWFAQGGDYGQLLLEDIKIRKFIMKTLPQAAISKVVIERPAKLCRISIYAARPGVIIGKKGADIEKLRKKLDSMTESGVSLNIVEIRKPEIDAQLVAQGIADQLERRVAFRRAMKRAVQSALRLGAQGVRITCGGRLGGAEIARTEWYREGRVPLHTLRANVDYAEAEAHTAYGVCGIKVWIFKGEIMAHDPLAQDRLMVEAQTSGVRPTR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PSPB_MOUSE
Sequence: MAKSHLLQWLLLLPTLCCPGAAITSASSLECAQGPQFWCQSLEHAVQCRALGHCLQEVWGHAGANDLCQECEDIVHLLTKMTKEDAFQEAIRKFLEQECDILPLKLLVPRCRQVLDVYLPLVIDYFQSQINPKAICNHVGLCPRGQAKPEQNPGMPDAVPNPLLDKLVLPVLPGALLARPGPHTQDFSEQQLPIPLPFCWLCRTLIKRVQAVIPKGVLAVAVSQVCHVVPLVVGGICQCLAERYTVLLLDALLGRVVPQLVCGLVLRCSTEDAMGPALPAVEPLIEEWPLQDTECHFCKSVINQAWNTSEQAMPQAMHQACLRFWLDRQKCEQFVEQHMPQLLALVPRSQDAHITCQALGVCEAPASPLQCFQTPHL
What is the function of this protein?
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.  SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
What are the official names of this protein?
Pulmonary surfactant-associated protein B, SP-B, Pulmonary surfactant-associated proteolipid SPL(Phe).
What are the subcellular locations of this protein?
Secreted, extracellular space, surface film.
Protein: SYY_MANSM
Sequence: MSDINVVLAELKRGVDEVLSEADLIEKLKENRPLKIKLGADPTAPDIHLGHTVVLNKLRQFQNFGHEVIFLIGDFTGMVGDPSGKNKTRPPLSREDVLRNAETYKQQIYKILDPQKTRIVFNSDWLGKLGTEGMIRLASNYTVARMLERDDFKKRFTEKQPIAIHEFIYPLLQGHDSVALEADVELGGTDQKFNLLVGRELQKSAGQKPQVAMTLPLLVGLDGEKKMSKSLGNYIGVTDAPNDMFGKIMSISDDLMWDWYDLLSFRPLTEIAQFKEEVKNGRNPRDVKILLAKEIIARFHSEADADTAEQEFINRFQKGAMPDEMPEFTFEGEIGLANLLKEAGLVASTSEANRMVQQDGVKIDGEKVEDAKTTISASTHVYQVGKRKFARVTVR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_CLOP1
Sequence: MKKIILAGGCFWGVEEFLSRINGVVSTEVGYANGRTENPTYEDICTKNTYFAEVCLVNYDENIISLKELLAKFWTIIDPTSLNKQGNDVGSQYRTGIYYVDPSDLEEILNSKEELQKSYSKKIVTEVKPLENYYKAEEYHQKYLKKNPNGYCHIKLD
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: CH60_CHLCH
Sequence: MTAKDIFFDTDARAKLKVGVDKLANAVKVTLGPAGRNVLIDKKFGAPTSTKDGVTVAKEIELADAVENMGAQMVREVASKTSDVAGDGTTTATVLAQAIYREGLKNVTAGARPIDLKRGIDRAVKEVVAELKAISRSISSKKEIAQVGTISANNDPEIGELIAEAMEKVGKDGVITVEEAKGMETELKVVEGMQFDRGYLSPYFVTNSDTMEAELDNPLILIYDKKISNMKELLPILEKSAQSGRPLLIIAEDIEGEALATLVVNKLRGTLKVCAVKAPGFGDRRKAMLEDIAILTGGTVISEEKGYKLENATLSYLGQAGSVSLDKDNTTLVEGKGASDAIKARINEIKGQIEKSTSDYDTEKLQERLAKLSGGVAVINIGASTEVEMKEKKARVEDALHATRAAVQEGIVVGGGVALIRAIKGLNNAQADNEDQKIGIEIVRRALEEPLRQIVANTGTQDGAVVLEKVKEGEGDFGFNARTETYENLVEAGVVDPTKVTRSALENAASVAGILLTTEAAITDIKDDKMDMPAMPPGGMGGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF5A_TRYB2
Sequence: MSDDEGQFAEGGAQVGSLTYPMQAGALKKGGYICINGRPCKVIDLSVSKTGKHGHAKVSIVALDIFTGNKMEDQAPSTHNVEVPFVKTATYSVLDIQEDREDPSKPAHLSLMDDEGETRDNLDMPPNAELAGQIKEQFDAGKDVLVVVVSAMGIDQILSFKNAAER
What is the function of this protein?
mRNA-binding protein involved in translation elongation.  Has an important function at the level of mRNA turnover, probably acting downstream of decapping (By similarity).  Critical for the efficient synthesis of peptide bonds between consecutive proline residues.  Can resolve ribosomal stalling caused by consecutive prolines during translation (PubMed:26082486).  Required for cell growth during both bloodstream (BF) and insect procyclic (PF) life cycle stages and for survival of the bloodstream form (PubMed:26082486).
What are the official names of this protein?
Eukaryotic translation initiation factor 5A, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the cytoplasm in the procyclic insect (PF) life cycle stage.
Protein: PLSX_YERPA
Sequence: MACLTLALDAMGGDFGPCVTVPASLQALASNPQLKLLLVGNPDTITPLLANADSLLLERLQVIPAEHVIASDAKPSQAIRASRGTSMRVALELVKNGEAAACVSAGNTGALMGLAKMMIKPLEGIARPALMTVIPNQRRSKTVVLDLGANVECDSTMLVQFAVMGSVMAEEVVGIVEPRVALLNIGEEENKGLDNIREAAAVLKNTPAINYIGYLEGNDLLTGKTDVMVCDGFVGNVTLKTMEGVIRMFLSLLKPSGEGSKQSWWLKLIGRWLQKRVAKRFGHLNPDQYNGACLLGLRGIVIKSHGAANQRAFAVAIEQAVQAVQRQVPERIAARLEAVLPKSD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: Y718_STRU0
Sequence: MTQEIYEYANKIERALRNLPEYKKVVAAKEDIEKDSEASNIFEEFFKLQAKLKEMIQNGQTPSNEEQETIHQLSSKIESNELLKAYFEAQQSLSVYINDIERIIFNPLKDLI
What are the official names of this protein?
UPF0342 protein SUB0718.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: PCDA2_HUMAN
Sequence: MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-2, PCDH-alpha-2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ANPRB_MOUSE
Sequence: MALPSLLLVVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRALPVDLRFVSSELDGACSEYLAPLRAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVASGFAAKNEHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTQEQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELAPSLMNLIAGCFYDGILLYAQVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTGRPIPWVKGAPPLDNPPCAFDLDDPSCDKTPLSTLAIVALGTGVTFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNSDRYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFAIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGEQKGPPGLL
What is the function of this protein?
Receptor for the C-type natriuretic peptide NPPC/CNP hormone.  Has guanylate cyclase activity upon binding of its ligand.  May play a role in the regulation of skeletal growth.
What are the official names of this protein?
Atrial natriuretic peptide receptor 2, Atrial natriuretic peptide receptor type B, ANP-B, ANPR-B, NPR-B, Guanylate cyclase B, GC-B.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: DNAK_SALRD
Sequence: MGKVIGIDLGTTNSVVAVMEGDDPEVIENAEGSRTTPSVVAYKDDGERLVGAPAKRQAITNPENTVSSIKRFMGRFYDEVEDEIEEVPYEVVRGENDTARVQIGDRKYTPQEISAVVLQKLKQTAEDYLGQEVTDAVITVPAYFNDAQRKATQEAGEIAGLNVQRIINEPTAASLAYGLDDESDQVVAVYDLGGGTFDVSILELGDGVFEVNATYGDTHLGGDNFDKRLIDHIADEFEQDTGIDLRDDPMALQRLKEAAEEAKIELSSAKTTTINLPFITATDEGPQHLNMDLNRATFENLIEDLVEKTVPQMEKALDDAGHSKSDVDEVILVGGSTRVPLVQETVEDFFGKQANKSVNPDEVVSLGAAVQGGVLSGDVDDVLLLDVTPLNLGIETLGGVMTTLIEANTTIPTKESEVFSTAADNQTSVEVHVLQGDREMAKDNRTLGRFHLDGIPPAPRGTPQIEVTFDINADGILNVSAEDKDTGKEQSIRVEANSGLSDEEIEKMKEEAEQHAEEDERRKERADTINEANSMAYSVEQGLEEYGDKIPEDKRSTLQEALDALNEELETASADEDITALEDALEELNAAWSAAGEEIREAQQQQAQQGAAAGAGAGAAGAGAAAGAEGPAGGPTGGPASGNGAADSDEEDVQDADYEVVDEGDDE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: AROB_MICAN
Sequence: MAICIPVNLPDRSYNILIEKGSLANLGGEMSQLSLGKKVLLVSNPEIFDYYGQIAVNSLEKAGFAVFTHLIPAGENYKTLDAIAQVYDSALAHRLERSSTMVALGGGVIGDMTGFAAATWLRGVNFVQVPTTLLAMVDASIGGKTGVNHPQGKNLIGAFYQPKLVLIDPDVLKTLPVREFRAGMAEVIKYGVIWDAELFQQLEDSDNLASFSQIDGELLQTIITKSCQAKADVVSKDEKEAGLRAILNYGHTIAHGIESLTGYTSVNHGEAVALGMVAAGAIAVKLGMWTAGENQRQTDLIEKAALETRMPPLNADEMVNALTADKKVKDGQVRFILPTAIGQVTISDRVTPTLVREVLSPTESGQ
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMA1_STAA1
Sequence: MGIIAGIIKVIKSLIEQFTGK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 1 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: NH133_CAEEL
Sequence: MPPALYLSGPCEICEQPAHGNHFGVLSCRACAAFFRRAALQNAKYQDRVCRKGNCIGNDLYRCKICRLKKCCEVGMNSSKFQNDRDLISSSLRPTNYTKTSAPQSLANFLGRPEFILCCEPDKASSTKRLVDVTSLVDKAWAIFQEDAAYSWSPNHYPNSLEKLTFEMEEIKLKESSKKLEIATTIGRNEALLFLEQSFLGAAQWFARLPEFSMLDPQIKIDILKTSWMIWARLDKLAATADFHRQKLLGNDVYMWTDNTCMNPGNVKIDIKWSSNYSVEQLRGFLVPDIEKYWRHALSDLVELDPTNVELNFMLIQLCLNSAGQKYQGHVLEATEKILQIQSDNMHEYYTKKLKLVNYSGRLARLMKINRAIEADVRDRKEKNHIAKVFDLFFVEYSHPEMFEFS
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-133.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAD_BRUO2
Sequence: MRVLGIETSCDETAAAIVERDDMGEGRILSNVVLSQIAEHEPYGGVVPEIAARAHAEALDRLVDRALNDAGLKLYEVDAVAATAGPGLIGGLIVGLMTAKALAMAAQKPFYAVNHLEGHALTARLTDGLPFPYLLLLVSGGHTQMVLVRGIGDYERLGTTIDDALGEAFDKTAKLLGLPYPGGPAVERMALQGDQKRFALPRPLKGEARLDFSFSGLKTAVRQTATELVPLTDQDVTDICASFQAAVADTLSDRVGRSLERFKTEFPDCATPSLVVAGGVAANKTLRAALENLCTRHGFAFIAPPLNLCTDNAAMIAWAGAERAATQAPDSLDIAPRSRWPLDEKSAPVFGTGRRGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_SYNR3
Sequence: MLALKISVYSVVFFFIGIFMFGFLASDPSRTPSRKDLEE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RUTD_SHIF2
Sequence: MKLSLSSPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTMLVSVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: RISB_XANC5
Sequence: MTHYEGDLRPTTARFAIIASRWNARITDVLVAGARQSLAGNGIGEDAIDVIRVPGAWEIPIAANRVAQSGQHGAIIALGCVIRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVERVEDAEARAGGSHGNKGEECALAALELVNLMELLP
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: KITH_CHICK
Sequence: MNCLTVPGVHPGSPGRPRGQIQVIFGPMFSGKSTELMRRVRRFQLAQYRCLLVKYAKDTRYCTTGVSTHDRNTMEARPACALQDVYQEALGSAVIGIDEGQFFPDIVEFCEKMANTGKTVIVAALDGTFQRKAFGSILNLVPLAESVVKLNAVCMECYREASYTKRLGAEREVEVIGGADKYHSVCRACYFQKRPQQLGSENKENVPMGVKQLDMPASRKIFAS
What is the function of this protein?
Cell-cycle-regulated enzyme of importance in nucleotide metabolism.  Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate.  Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration.
What are the official names of this protein?
Thymidine kinase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.