PharMolix/UniProtQA huggingface dataset:
Protein: MBTK_MYCBO
Sequence: MTKPTSAGQADDALVRLARERFDLPDQVRRLARPPVPSLEPPYGLRVAQLTDAEMLAEWMNRPHLAAAWEYDWPASRWRQHLNAQLEGTYSLPLIGSWHGTDGGYLELYWAAKDLISHYYDADPYDLGLHAAIADLSKVNRGFGPLLLPRIVASVFANEPRCRRIMFDPDHRNTATRRLCEWAGCKFLGEHDTTNRRMALYALEAPTTAA
What is the function of this protein?
Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.
What are the official names of this protein?
Lysine N-acyltransferase MbtK, N-acyltransferase MbtK, Mycobactin synthase protein K.
What is the protein family that this protein belongs to?
Belongs to the lysine N-acyltransferase MbtK family.
Protein: RUTB_ECO26
Sequence: MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: DAPB_TOLAT
Sequence: MTAPIRIALMGCQGRMGKALLEAIRANEQVTLGTALERPGSTVIGLDVGDLNGLGAMNVLIADDLEKVKDQFDVIIDFTRPEVTLKNLAFAVANNKRIVIGTTGFDDAGKAAINEAAKKIGIVFASNFSVGVNLVFKLLEQAAKVMGDYTDIEIIEGHHRHKVDAPSGTALSMGEVVAKTLGRDLKQCAVYGREGITGERDRNTIGFATIRAGDLVGEHTVMFADIGERVEITHKASSRLTFANGAVRAANWLKDQPCGLFDMQDVLNLK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DABA_ACIF2
Sequence: MPTPATIKSYQDIKANIEGACQRIAPLWPLKHFVAVNPYVGLRDQPFWRADQTLRKITGKGLTMPRPYYEEQIANGRIIQEDLDEALKQMHSNWSVTQLKQVMKQRSASRNVPFPVFADAMFADDRRDWPGFVVERISQYCAAYFDEGQATWSMPWRDDPMYQAWLKFMHFDKSPRMVGLRGIGEAAAALPAAAETAIALALKELSVPFDLIDDYLFAALLSIGGWAGWARYLRWQAELKGETDQSLRDLLAIRVCWDAILHKTCADIAVRKQWHLMLHTQQNRAIEKPSEHVDAILQTALEIGYQRSLIKSLKEASRPSNTVIERPVAQAAFCIDVRSEIIRRALETVAPGIQTLGFAGFFGVLMEYVPFGSNAPKGHLPVIFNPPYRVCEDLSHASEDETQRHAAKRQLRLRVATAWKSFKTSAVSTFTFVEATGLLYAPKLFGDSMGWTRTVPHPDERGLDSGTKQRLRPRLIASGNGKSSAKSTGIPETERAGVGEFILKNMGLTQTFARLILLAGHGSTTVNNPQGTGLDCGACAGQTGEASARIAVTLLNDPATRRGLEEKGLKIPKDTYFIAGLHDTTTDEVTIFDTEDLPTTHAKDLAQLRQWLADAGELTRLERATLLGTASQAPEVVTRDMRRRTRDWAEVRPEWALAGNAAFIAAPRQRTRGVDLEGRAFLHDYDWHKDAGFSTLELIMTAPMVVANWINMQYYGSMVDNLRFGSGNKVLHNVVGGSIGVLEGNGGDLRVGFALQSLHDGKRWIHEPVRLNVVIEAPQAEMESIISRHILVRELVDNGWLYLFQIDDDGSVYRRVCDKQWPRMT
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CAN5_CAEEL
Sequence: MTRSEKTRHFGNQNYEKLRKICIKKKQPFVDTLFPPTNQSLFLEQRQSSDIVWKRPGELHPDPHLFVEGASPNDVTQGILGNCWFVSACSALTHNFKLLAQVIPDADDQEWSTKHAYAGIFRFRFWRFGKWVEVVIDDLLPTRDGKLLFARSKTPNEFWSALLEKAFAKLYGCYENLVGGHLSDALQDVSGGVAETLHVRKFLKDDPNDTELKLFNDLKTAFDKGALVVAAIAARTKEEIEESLDCGLVKGHAYAVSAVCTIDVTNPNERSFTSFIMGSKRKQNLIRLQNPWGEKEWNGAWSDDSPEWQNVSASQLSTMGVQPANSDSDDGDFWMPWESFVHYFTDISLCQLFNTSVFSFSRSYDEQIVFSEWTTNGKKSGAPDDRAGGCHNFKATFCNNPQYIFDIPSPNCSVMFALIQNDPSEGLKKREPFVTIGMHVMKVENNRQYRVHTAMHPIAISDYASGRSVYLHLQSLPRGRYLLIPTTFAPKEQTLFMLRVYSDEHIHFSPLTKHAPKLGLLKCKSAQSVTRLTIHGVDFNSASTGTHNVYAILKDSRKSFRTKTLSGVKSIQWDEQFLFHKSKNRQQYKIEVWEDRKMARDHLLAQSVIIALIDNENRDTTLQLTDPRGTVIGTVSVTVSAFDDPMYL
What is the function of this protein?
Required for the correct female sexual development of the soma and germline in hermaphrodite animals, while being fully dispensable in males.  Has calcium-dependent proteolytic activity and is involved in the cleavage of tra-2, for which it acts as a potentiator.  Capable of calcium-dependent autolysis (PubMed:10783162).  Part of the necrosis cell death pathway (PubMed:12410314).  Required for necrosis of intestinal cells induced by B. thuringiensis endotoxin Cry6Aa (PubMed:26795495).
What are the official names of this protein?
Calpain-5, Sex-determining transformer protein 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
Protein: O51A2_HUMAN
Sequence: MSIINTSYVEITTFFLVGMPGLEYAHIWISIPICSMYLIAILGNGTILFIIKTEPSLHGPMYYFLSMLAMSDLGLSLSSLPTVLSIFLFNAPETSSSACFAQEFFIHGFSVLESSVLLIMSFDRFLAIHNPLRYTSILTTVRVAQIGIVFSFKSMLLVLPFPFTLRSLRYCKKNQLSHSYCLHQDVMKLACSDNRIDVIYGFFGALCLMVDFILIAVSYTLILKTVPGIASKKEELKALNTCVSHICAVIIFYLPIINLAVVHRFAGHVSPLINVLMANVLLLVPPLMKPIVYCVKTKQIRVRVVAKLCQWKI
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 51A2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTFAH_ECO57
Sequence: MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGMLAREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAASSDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIVASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVSRAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLTSDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSLMKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FruAB PTS system is involved in fructose transport.
What are the official names of this protein?
Multiphosphoryl transfer protein, MTP, Diphosphoryl transfer protein, DTP, Phosphotransferase FPr protein, Pseudo-HPr.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_COXBN
Sequence: MSSFILAIDQGTTSTRAILFNEEAKLVHYHHVEITQYFPQGGWVEHDPEEIWDSTLLCCRNVLEEASLRAADIAALGISNQRETTILWDRHTGQPLYRAIGWQDRRTVNFCEQLASQAGVLAKFVEKTGLILDPYFSCSKIKWILDNIKGAYEKAKRGELAFGTVDSYLLWKFTGGKCHATDATNASRTGLFNINQQRWDDELLTLFDIPKSLLPTVLDNCAQFGFTDLDLLGHKIPITAMIGDQQAAAVGQACIKPGMVKSTYGTGCFMLLNTGDQIIHSRNRLLATIAYRLNDTVTYGLEGSIFIAGAAVKWLRDPLHLIEKANDSESMASSVEDTGGVYLVPAFTGLGAPYWDPNARGALFGLTRNTQREHIVRAALEAVCYQSKDLVRAILNDGANLTTLRVDGGMAANNWLLQFLSDILGVNVDRSRCIESSALGTAFLAGLGAGLFDSLEEMTGLWQADRHFIPQMDPKKREELYDGWQKAVEKTLTPAAPLLFP
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: APOE_EUMJU
Sequence: MKVLWAALVVALLAGCWADVEPESPLEENLEPELEPKRELEQEVEPEAGWQAGQPWELALARFWDYLRWVQTLSDQVQEEVLSNQVTQELTTLMEETMKEIKAYRAELEEQLGPMASETQARVAKELQAAQARLRSDMEDVRTRLSQYRGEVQAMLGQSTEELRARFASHMRKLRKRVLRDAEDLQKRLAVYRAGVREGAERSVSTIRERLWPLLEQARTRHAKVDALATQPLRERVNALGQQLRGRLEEVGSRARSHLDEVREQMEEVQAKMEEQANQMRQQAEAFQARLKGWFEPLVEDMQRQWAVLVEKVQAAVGTSPTTPPVETK
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: SPSS2_METLZ
Sequence: MKCAGQIEARAVEESSINLDPIQAAGRLTPEAMKAVIAWGDGYSVCDNCHKPFRLDYVTKPPIADFHEEAAKWLGMDKIQLVPGARRAFQEVTGALVGKGEPVIMTGMGHYTAYLSVEVVNGVVREIRPTADHHITADAAAESIENAVREFGYAPKLVFVDAVDFMYGNMHEVEKIAKVAHQYDIPVLYNGVYTVGVLPVDGKKLGVDFVVGSGHKSMAAPAPSGILATTDEYAEIVLRTTKIQGDITGRKFGIKQVGILGCSLMGDPAVGLIASFPRVKERVNHFDEELKNHKIVTDALLSIEGTKVASEYPRKHTLTRMDTAGSFDVIARTHKKRGFFLSSALNKRGITGIMPGVTKQWKFNTYGLTKTQAEYLADSFIEIAEENSMVVG
What is the function of this protein?
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
What are the official names of this protein?
O-phospho-L-seryl-tRNA:Cys-tRNA synthase 2, Sep-tRNA:Cys-tRNA synthase 2, SepCysS 2.
What is the protein family that this protein belongs to?
Belongs to the SepCysS family.
Protein: PANB_ROSCS
Sequence: MRKTITDIQQMKVRGEPIAMLTAYDAVTAALFDAAGVPMLLVGDSLGDNVLGFGSTIPVTIDDMVRHTAAVARGAQSALIVADMPFLTYATLEMAVVAARRLMQEGGAQAVKLEGGQAMTPIVRRLVECGVPVMGHLGYTPQSAHVFGKVRVQGRSVAAARRLIEDALALESAGAFALVLELVPAPLAAAITERLRIPTIGIGAGPHCDGQVQVSTDMLGLRDDFKPRHARRFADLAPIIRNAAAAYIAAVGERSFPADEHSSRMDETVLREALEGLS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_VHSVM
Sequence: MEGGIRAAFSGLNDVRIDPTGGEGRVLVPGEVELIVYAGPFGTDDGKVIVDALAALGGPQTVQALSVLLSYVLQGSAQGDLEAKCKILTDMGFKVTQSPRATGIEAGILMPMRELAQTVNNDNLMDIVKGALMTCSLLDKYSVDKMIKYITKKLGELGSTQGVGELQHLSADKAAIRKLAGCVRPGQKITKALYAFILTEIADPTTQSRVQSMGALRLNGTGMTMIGLFTQAANNLGIPPAKLLEDLCMESLVESARRIIQLMRQVSEARSIQERYAIMMSRMLGESYYKSYRLNDNSKISYILSQISGKYAVDSLEGLEGIKVTEKFREFTELVAEVLVDKYERIGEDSTEVSDVIREAARQHARKASDKPEPKARNFRSSTGRGKEQEKEESDDDDYPGDSD
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: PAM71_ARATH
Sequence: MLSLNLSESLRIPFQNPRPPKSDFSSTSSSPSSSSRRCVSAYPIPIGFSVRNQYFSRCLTQLRRNESQQLGFRCFQRNDAACYLEKAESEEHDRNLDVLVESSIAHSRREIQRVLMFLAVSGSVALLGTDPAFAASSIPNVTQSLVTSFGDLGDISSGFASAFLLIFFSELGDKTFFIAALLAARNSAATVFVGTFGALGIMTIISVVLGRTFHYVDEVLPFRFGGTDLPIDDIAAVCLLVYFGVSTLLDAVSDEGKADEEQKEAELAVSELSGNGAGIVAAANTIISTFALVFVAEWGDKSFFSTIALAAASSPLGVIAGALAGHGAATLLAVLGGSLLGNFLSEKAIAYVGGVLFLVFAAVTVAEIVT
What is the function of this protein?
Mn(2+)/H(+) exchanger, which transport Mn(2+)from the chloroplast stroma into the acidic thylakoid lumen (PubMed:27020959).  Might be a chloroplast-localized Ca(2+)/H(+) antiporter (PubMed:27302341).  Regulates Ca(2+), Mn(2+) and pH homeostasis (PubMed:27302341).  Required for chloroplast development (PubMed:27302341).
What are the official names of this protein?
Protein PAM71, chloroplastic, CA(2+)/H(+) ANTIPORTER 1, GDT1-like protein 1, PHOTOSYNTHESIS AFFECTED MUTANT71.
What is the protein family that this protein belongs to?
Belongs to the GDT1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein. Thylakoid.
Protein: PIPNA_RAT
Sequence: MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAIYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQEKRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:7568025, PubMed:18636990).  Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (By similarity).  Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol transfer protein alpha isoform, PI-TP-alpha, PtdIns transfer protein alpha, PtdInsTP alpha.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HISX_METMA
Sequence: MIIMLFKKLSDVSEAEMQRLISRGSGLADVGDTVSAVLSDVRMKGDAALREYTKKFDKVELANFEVSEEEFEKALSEIGSELLGHLRIAAENIRAFHRAQMPETTWFMELQPGVVLGQKATPLESVGAYAPGGRASYPSTVLMTVIPARVAGVEQVIVCTPPRADGSVHPLTLAAAKVAGADKVFKLGGVQAIGAMAYGTETVPRVDKIVGPGNVFVTSAKMQVRDIAEIDFPAGPSEVLIIADESADAAMAASDIIAQAEHDPNAVSVLVTTSETLAEEVEQEVLAQAESTARSEIVKISLENAAVLIADSLDQCIDFSNKFAPEHLEIMVEDSDFVLDRIKNAGSIFIGNYAPVPVGDYASGTNHVLPTAGYAKIYSGLNINHFLKYSSIQKISKSGLESLKETVIALAEEEGLKAHADSIRARFGYRPSK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: CCZ1_CANGA
Sequence: MSQSQSHGSGSPLKYVIVFRPGENKGEQEDSVVSEQLLLHHAFEDTELITLSAKLGKIGIIQALWTLSEDTNDTCKIIETEQETMITIKVEGEFYITLAIGVDPDLLAIPNPIFEGHLWNCYHFFTIKYGDFTSFEKHVLTDLLNEHFVSFWNDLYRKPESLTRNFLQYLCHDFYKVADLDPNGDKQWEATIIQDLLVQTENYLGIKDILVYNIPSTESTYVGKCKYGLIRNFCNEFEDLGHFSNWLQHIHTVFGKISSHVLAENVHYELHSGQLEQTNSDGIRDGNDLNLSDNNNETDSNTFSQLSTNFMHNLTLPITFAYDAIQEVGNTTGINNSVSLFMNYLPKWQNNSTASENEKNKTKARYGYLISPLAFDSLPKSYKLKKMHLKFNGEERKPYHVLFWYYNDVLVVIICNESFDSIWSKEYLNELNKHLENSIKTLYDQNLYDLPNTDNHSNKKNDILNFAYLITDKKRNKLYSSFPDLSWFNEQQETLYRTTLELVSNGLEQLRPQITANELSITTIDSNKQWGLDIMGNILSMLPSNSPVPVTKDASIPLMKKLNFLDKLNEKVLRDISIETLRAIETLSQSINSNIQEEKLLKTSDGILLYIRNDCNNLTIILKNWIQDTKHQTRALKYKNHTLNSYSTSIEDSNLFKNLGPDVISWYSEYKQILQDDSS
What is the function of this protein?
In complex with MON1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.  The CCZ1-MON1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.
What are the official names of this protein?
Vacuolar fusion protein CCZ1.
What is the protein family that this protein belongs to?
Belongs to the CCZ1 family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: EPN3_MOUSE
Sequence: MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGYSRRSRGSPSSYTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAERPVPPASHRDEDLQLQLALSLSRQEHEKGVRSWKGDDSPVANGAEPAGQRRQRDREPEREERKEEEKLKTSQSSILDLADIFAPAPALPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGNALSRSQPWDLLPTLSSSEPWGRTPVLPSGPPIADPWAPSSPTRKLPSTGADPWGASMETSDTSALGGASPFDPFAKPLESTEPKESRDSAQALPTGKSPSTVELDPFGDSSPSCKQNGMKEPEALDLGVLGEALPQQPGKEARPCRTPESFLGPSASSLVNLDSLVKAPLAARTRNPFLTGLGVPSPTNPFGAGDQGRPTLNQMRTGSPALGLPPGGPVGAPVGSMTYSASLPLPLSSVPVGATLPASVSVFPQAGAFAPPPASLPQPLLPTSGPMGPLPPQAGTNPFL
What are the official names of this protein?
Epsin-3, EPS-15-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the epsin family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus (By similarity).
Protein: G3P_HALS3
Sequence: MIRVGINGYGTIGKRVADAVAAQPDMTVAGVAKTSPNFEATQARKRGFDLYTAVEDRADQFPAAGIETAGPVDDLIADSDVVVDATPSGVGAENRSRYAAHDTPAIYQGGEDASVADVSFNARANFEAAADADHVRVVSCNTTGLSRLLAPLREQYGIEKVRATLVRRGGDPGQTDRGPINDILPDPITIPSHHGPDVNTIFPDLDIDTLGMKVPATLMHMHSINVTLERDPDAADVRDVLAGQSRIMLLDDDLGIDGTGPLKEYAQDMGRPRGDLWENCLWGESVTMDGRDFYCFQAIHQESDVVPENVDAVRAIAGDADAAESIATTNDALGI
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_XYLFT
Sequence: MDTTTMPNLLWHKPGVAIDASIQTFLAADDVLLDREFFLYDITASTAHAQALQRIGLLTPDELDNILRELQHLSDEYRNGTFLLDTQYEDGHSAIESRLTERLGDTGRKIHTGRSRNDQILVATRLWLKDRLTQLSTLNRDIAHHALQRAAAEQHLPMPGYTHLQRAVVSSAGMWWAGWAESFIDNALRAADTLALIDCNPLGTAAGYGVNLPLDRPHTTTALGFARLQVNPICAQLSRGKFELAALEALGSATLDLRRIAWDLSLFTTSEFAFITLPPEYSTGSSIMPNKRNPDVIELMRATHASVAAARTEIEQLLSLPSGYHRDLQNSKGAIVRGFNRGLAALELLPALLSRLQWRPDTLRAAIDPGMYATDAAIEAAIAGIPFRDAYQMAAKTADTAAQDRTPETSLTARRSPGAAADLCLETLRARWHTLTQPTSDPDPR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIAB_XENLA
Sequence: MNSVGEECTDMKREYDQCFNRWFAEKFLKGDGSGDPCTELFRRYRECVQKAIKDKDIPVDGVDFMGPSKSKTEADGSS
What is the function of this protein?
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes.  The triap1:prelid1 complex probably functions as a phosphatidic acid (PA) transporter across the mitochondrion intermembrane space to provide PA for cardiolipin CL synthesis in the inner membrane.  Likewise, the triap1:prelid3a complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo).  Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (By similarity).  Required for pronephros development; probably involved at an early stage in the formation of pronephric components derived from the somatic layer (By similarity).
What are the official names of this protein?
TP53-regulated inhibitor of apoptosis 1-B, p53-inducible cell-survival factor-B, p53csv-B.
What is the protein family that this protein belongs to?
Belongs to the TRIAP1/MDM35 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion intermembrane space.
Protein: OBG_GEOMG
Sequence: MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPDGGDGGKGGDVIFTVDPNLSTLMDLRYRPHLKAGRGKNGMGKDRHGANGDDLTIPVPPGTIVKDAETGEILADLTEPGQTVVLLKGGRGGQGNARFTTSTNRAPKFAQPGEDEEERWLRLELKLMADVGLLGFPNVGKSSFITKVSAARPKIADYPFTTIKPNLGVVSYKNYRSFVVADIPGIIEGASEGAGLGHRFLKHVERTNILLHLIDLSWIPDRDPIREYETLNRELALFSPELAGKEQIAVINKIDLPVVRENLPSVIDWFKERGIAVFPISAATGEGIPTLLDEIARHLWGQAEEEW
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3PC_GINBI
Sequence: MSSTGKIKIGINGFGRIGRLVARVALLRDDIELVAVNDPFISTDYMTYMFKYDSVHGQWKKHEVKVKDSNTLLFGEKAVTVFGCRNPEEIPWGETGVEYVVESTGVFTDKEKAAAHIKGGAKKVVITAPSKDAPMFVVGVNEHEYKPDLAIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSNKDWRGGRGAGFNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTPDVSVVDLTVRLEKPASYDEIKAAIKEESEGKLKGILGYTEDDVVSTDFIGDNRSSIFDAKAGIALSDNFVKLVSWYDNEWGYSSRVIDLIVHMASTV
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.