PharMolix/UniProtQA huggingface dataset:
Protein: ECM29_YEAST
Sequence: MSISSDEAKEKQLVEKAELRLAIADSPQKFETNLQTFLPPLLLKLASPHASVRTAVFSALKNLISRINTLPQVQLPVRALIVQAKEPNLAAQQDSTNVRLYSLLLASKGIDRLSLQDRQQLLPLVVSNISCLTGTVAARMFHILLKLILEWVAPQESSHEQEEFVQFLQLDNDGFSFLMRQFTRFFLLVPSKQVQVSQQPLSRGYTCPGLSLTDVAFFTYDAGVTFNKEQLNKFKKAIFQFVCRGMAATQTIEQSPRMIELMEFLCVVSTDSTNLSDDAAQFMKRFPMPYENEEFITFLQTLYIGNTANGRPPVKAILQEKILSILNRSHFATTKAECISLICSIGLHSSEYKLRSLTLSFIRHVAKLNYKNLNPASSSPSSTDFSTCIVSLIRNNLHAEGWPKLQLGPQTPAFNTAILQRQLQYETLGDILKRDFELVSDLSYIEFLFESLKNDLPQFRSSIQESLLSLVGHLSILPQQSKLKLKNLLRKNLSIDEQQREDNNDAVNSIMALKFVSIKFTNAAFPFHDPEARLFNIWGTVRTNRFDIIEESFKGLQPFWFRVNNASINTSATVKTSDLLGSHLSETEFPPFREFLQVLIDQLDSEAASITRKSLNNAVRFSKQCLISNAIYGKKTMVIQDEDWSVRIDKALELDDTVVSRVNEMVQGMNDDIFIRYLTLLSNEFTATNSKGEQIAIFPYQDPIFGSVLLTLLNFVSNNVLRRLEILVPDLYHLVIMKFQSLSDNDLAVCATIIGIISTAIADSTHVKRITKIAQSQTMAETYVASYVVPRLYLKDQTNHIESDSILNLLNILTTHLSHPGTNKDMILKLVCQVTKFGLLLQVSAQERKDFLKKVMDTIQDKLINDVTAIQTWSYLSLYSTDLENSSLFQEKLLETNVSKQNDFLFSVGESLSVVAGKWSSKYLIKQIDIPNFNVEIMQQKFPATNVTTILDEIFSGCDSTKPSLRKASCIWLLSYIQYLGHLPEVSSKCNDIHLRFMRFLADRDEFIQDSAARGLSLVYEIGGSDLKESMVKGLLKSFTESTAGSASTSATGISGSVSEETELFEPGVLNTGDGSISTYKDILNLASEVGDPALVYKFMSLAKSSALWSSRKGIAFGLGAIMSKSSLEELLLKDQQTAKKLIPKLYRYRFDPFQAVSRSMTDIWNTLIPESSLTISLYFNDILDELLCGMANKEWRVREASTSALLQLIQSQPQEKFSEKMLKIWTMAFRTMDDIKDSVREVGTKFTTVLAKILARSIDVEKGVNPTKSKEILDNILPFLWGPHGLNSDAEEVRNFALTTLIDLVKHSPGAIKPFTPKLIYDFITLFSSIEPQVINYLALNAANYNIDANVIDTQRKNGVTNSPLFQTIEKLINNSDDCMMEEIINVVIKASRKSVGLPSKVASSLVIIILVKRYSIEMKPYSGKLLKVCLTMFEDRNESVNIAFAISMGYLFKVSALDKCIKYSEKLITKYFEPTSTENNKKVVGTAIDSILNYAKSEFDNVASVFMPLIFIACNDEDKDLETLYNKIWTEASSSGAGTVKLYLPEILNVLCVNIKSNDFSIRKTCAKSVIQLCGGINDSIPYPQIVKLFDISREALSGRSWDGKEHIVAALVSLTEKFSQTVADNNDLQESINHVMYTEVSRKSMKYVKKILPLYARYINVNPQEETITFLIEKAKEMIRLLGSESDDSEGSIKQTSDESTIKRIKPNTEITQKSSKENIENEEYVINLLKVSVDICNNSKSRYPMNLLEFIIDEIAYLFHNDRIIHTWRTQLAASEIGISIVGRFSTISSADFIQNVGRLWDQTFPINCNKETIENVKLQMIKFGGLIIQKIPSLQNNIEENLRLLNSIDSTSRIELELKNIGL
What is the function of this protein?
Stabilizes the proteasome holoenzyme, probably by tethering the 20S proteolytic core particle and the 19S regulatory particle.  The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome component ECM29, Extracellular mutant protein 29.
What is the protein family that this protein belongs to?
Belongs to the ECM29 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RLR09_PLAHL
Sequence: MRFCLVFIRLAAFVILSGGATSTTTDNDDTRLLQTSNIETAAVANVLHVMQSSESSKRLLRLNDQADISGHDEERSSLIEKGWKKLRKLIKKVWKYVKKPFKKTAKIIKKPFKSRTKNIHIVYYKSRF
What is the function of this protein?
Secreted effector that suppresses pattern-triggered immunity (PTI) in plant host.
What are the official names of this protein?
Secreted RxLR effector protein RXLR-C09.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Host nucleus.
Protein: YOO8_SCHPO
Sequence: MDLLAIDLDFDVSESKLERNKRLKQKVSIETDGWTPRVQCFGHLSKNGVVLGEEAYILEQSKFAAEEQYYLGNYSLAKKFAFQALDVPTDSSSIEYHRLSSGEINEIEDIIRRCEMKLENKQSN
What are the official names of this protein?
Uncharacterized protein C887.08.
Protein: LIPA_SALPB
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVVTERDALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDAEEPQKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIRAKSPEIKIETLVPDFRGRMDRALDILNATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNAEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPEEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRB1_PIG
Sequence: MGAGALALGASEPCNLSSAAPLPDGAATAARLLVPASPPASLLTPASEGSVQLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRAARALVCTVWAISALVSFLPILMHWWRDKGAEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGSPARPPSPAPSPGSPLPAAAAAAPVANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRVARGSCAAAGDGPRASGCLAVARPPPSPGAASDDDDDEEDVGAAPPAPLLEPWAGYNGGAARDSDSSLDERTPGGRASESKV
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  This receptor binds epinephrine and norepinephrine with approximately equal affinity.  Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity).  Involved in the regulation of sleep/wake behaviors (By similarity).
What are the official names of this protein?
Beta-1 adrenergic receptor, Beta-1 adrenoreceptor, Beta-1 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Colocalizes with RAPGEF2 at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity).
Protein: RNH2_LACDB
Sequence: MKINEIKDLLQADSIDPAILAELAKDDRKGVQKLLVSYQRRQEKLAKQKEEFLGRFSYEKDFWAKGQLVGGVDEVGRGPLAGPVVAAAVILPEDFSLLEVNDSKKLSPQKRLALYPKILQEAVAVGVGVMDNKVIDQINIYEADRLAMKQAVEALSTRPDVLLVDAMNVPVDLPQLELIKGDAKSNSIAAASIVAKVFRDSLMDDYARLYPDYAFDHNAGYGTKDHLEALRKYGPTPIHRLTFSPVSEMVGLKKAD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFTAP_BOVIN
Sequence: MPAKTPELEMMDEDRLIEEVLDKFVNCHEQTYEEFLRTFTHLSKDNVTKREAFGTNSSENNFTSIKFTQRNEPNDCRLSNKAIFLHTSSQCSEEEQIMIGDGQKAGSSFQGDLNRAGKVKVDNFLDIEDLDLDEEINPQLSKDVLLLPGQVEQEVSLSVPSYIPSVAIQPVTPGTKPRPTVKAADKQSKEIVGDEVQPFSLDEEFDYDAVVLTPKFTPAEMNAIKELSKQKTKSADLEDPHD
What is the function of this protein?
Seems to play a role in ciliary BBSome localization, maybe through interaction with IFT-A complex.
What are the official names of this protein?
Intraflagellar transport-associated protein, Protein HEPIS.
Protein: MOR1A_CHICK
Sequence: MEIAGKAVCVFLLLAIIKLRRSEGINRVSANLGHNTVMTCPTRTNISMVTWKINPKTGHQCTLAYRIDKDSTGKTNCSDRINWRSRPDWDQALEIQQVGKADEGNYTCEVVNADGNFHRLYHLTVIVAPRMALYCDDYGNPVCEAETEKSAAEISWVPESNSTPRADSHDNGTVTVVSWFAARSTNGKNPTCIVSHATLNETKSINCSSSYRDLILCIAIILSFLIIITFMAVIYYLKLHGCRFCHRSKPPDIIPTYSSQDDTVEVEPYTTYVQKENVIYNSVSDLTLRQNLPQGQSPAT
What are the official names of this protein?
Cell surface glycoprotein CD200 receptor 1-A, CD200 cell surface glycoprotein receptor 1-A, Cell surface glycoprotein OX2 receptor 1-A.
What is the protein family that this protein belongs to?
Belongs to the CD200R family.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: RL6_BURL3
Sequence: MSRVGKSPIALQGAEVKLADGAITVKGPLGTITQAINPLVNVANNDGTLNLAPVDESREANALSGTMRAIIANAVHGVTKGFERKLTLVGVGYRAQAQGDKLNLSLGFSHPVVHQMPEGVKAETPTQTEIVIKGINKQQVGQVAAEVRGYRPPEPYKGKGVRYSDEVVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CARB_LIMRJ
Sequence: MPKRTDIHKILVIGSGPIIIGQAAEFDYSGTQACLALREEGYETILVNSNPATIMTDKEIADHVYIEPLTVESLSRIIRQEYPDAILPTLGGQIGLNLAVSLSETGLLDELGIELLGTKLDSIDEAEDREKFKELMNELGEPVPASQTVNTVDEAVEFAHQCGYPVIVRPAFTMGGTGGGICHNDAEMRTVAKNGLELSPVTQCLIEKSIAGYKEIEFEVMRDAADNVMVVCCMENFDPVGIHTGDSIVFAPNQTLSDREYQMLRDCALKLIRALKIEGGCNVQLALDPQSFQYNVIEVNPRVSRSSALASKATGYPIAKMAAKIAVGLTLDEIKNPVTKTTFAEFEPALDYVVCKIPRWPFDKFTQADRHLGSQMKATGEVMAIGRTAEEALHKAVRSLEIDEKDLFSAEAHHAPTDMLEKKLRYPQDDRLFYLAETFRRGYSLQQTHDLTKISPYFLDIVKHLVELEDDLSTKPFDVETLITSKKYGFSDATIARLWHTSSQEVRKFRKQNEVLPVYKMIDTCAAEFASSTPYFYSAYDHENESQRTKKPSILVLGSGPIRIGQGVEFDYATVHSVKAIQRAGYEAIVINSNPETVSTDFSVSDKLYFEPLTLEDVLNVIDLEQPVGVIVQFGGQTAINLAEGLAKNGVNILGTTVDDLDAAEDREVFDQVITDLNLKQPIGLTATTHSAVIKAAEKIGYPVLVRPSYVLGGKAMETVYNQEELQQYLQQNASITADHPILIDAYLEGRECEVDAICDGKDVLIPGIMEHIEHAGVHSGDSMAVYPPQHFNDDIKRQIVTATEKLAVALKCIGIMNIQFIVHNHEVYILEVNPRASRTVPFLSKITGIEMAQVATRVILGQSLADQGFTNGLYPEPQTIHVKAPVFSFNKLANVDSYLSPEMKSTGEVMGTDTTYEKALHKAFSGAHIQVPNDGKILFTIENGDEKEVLPLAKRFAQIGYQVFTTPQTASHFKDNGIHIHQEISNIDELNCLLKAGQIDLVINTMRHDYEQDSLGFQIRQSTIAQNVPLMTSLDTVNALLRVKEDQSLEAITIK
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: PROA_SYNP6
Sequence: MATLSVDLEVQAQATRAAARQLAQWSGADRQRLLSAIATTLEQEAPRILAANQADCEAATTEGIAPALYARLKLDADKLAAAIAGVRDLAQLPDPLGQIQIDRELDEGLILQRLTCPVGVLGVIFEARPDAVIQIASLAIKSGNGAILKGGREAICSCQAIVAAIAQALAEQQAPVEAIRLLTSREETLALLKLDRYVDLIIPRGSNSFVRFVQDNTHIPVLGHADGICHLYVDQAAAIEKTVTITVDAKTQYPAACNAIETLLIHEAIAPQFLPVVAAALHEKGVSLRGDAAAQTIVPMEAATEEDWRTEYSDLVLAVRLVPSLDAAIAHINEYGSGHTDAIATEDAAAAAQFFSQVDSAGVYHNCSTRFADGFRYGFGAEVGISTQKLPPRGPVGLEGLVTYKYVLSGDGQIAATYSGAQAKPFLHRDR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_STAS1
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYTTDKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVISGSALKALEGDADYEQKILDLMQAVDDFIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEIEIIGMQEESSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVSRDDVQRGQVLAAPGTITPHTKFKADVYVLSKDEGGRHTPFFTNYRPQFYFRTTDVTGVVNLPEGTEMVMPGDNVEMDVELISPIAIEDGTRFSIREGGRTVGSGVVTVINE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C2_CERDE
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFILPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWKEEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDSITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLVAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFARIVSFGLRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARSC_NEIMB
Sequence: MPEIKIFHNPRCSKSRAALSLLEERGIAAEVVKYLDTPPDLSELKDIFNKLGLASARGMMRVKDDLYKELGLDNPNLDNDALLRAIADHPALLERPIVLANGKAAVGRPLENIEAVL
What is the function of this protein?
Involved in resistance to arsenate.  Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the ArsC family.
Protein: PIWI_ARCFU
Sequence: MMEYKIVENGLTYRIGNGASVPISNTGELIKGLRNYGPYEVPSLKYNQIALIHNNQFSSLINQLKSQISSKIDEVWHIHNINISEFIYDSPHFDSIKSQVDNAIDTGVDGIMLVLPEYNTPLYYKLKSYLINSIPSQFMRYDILSNRNLTFYVDNLLVQFVSKLGGKPWILNVDPEKGSDIIIGTGATRIDNVNLFCFAMVFKKDGTMLWNEISPIVTSSEYLTYLKSTIKKVVYGFKKSNPDWDVEKLTLHVSGKRPKMKDGETKILKETVEELKKQEMVSRDVKYAILHLNETHPFWVMGDPNNRFHPYEGTKVKLSSKRYLLTLLQPYLKRNGLEMVTPIKPLSVEIVSDNWTSEEYYHNVHEILDEIYYLSKMNWRGFRSRNLPVTVNYPKLVAGIIANVNRYGGYPINPEGNRSLQTNPWFL
What is the function of this protein?
Might play a role in defense against invading genetic elements, using short nucleic acid sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity).  Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA (PubMed:15800629).  Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA (PubMed:19187762).
What are the official names of this protein?
Piwi protein, AfAgo, AfPiwi, PIWI/MID domain protein, Short prokaryotic argonaute.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Short pAgo subfamily.
Protein: DPP10_RAT
Sequence: MNQTASVSHHIKCQPSKTIKELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEELLGKGFGLHNPEARWINDTDVVYKTDNGHVMKLNAETNATTLLLDNSTFVTFKASRHSLSPDLKYVLLAYDVKQIFHYSFTASYLIYNIHTGEVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEGIVFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFTGALYPKAKQYPYPKAGQANPSVKLYVVNLYGPTHTLELMPPDIFKSREYYITMVKWVSNTRTVVRWLNRPQNISILTVCESTTGACSRKYEMTSDTWISKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQITVRHLTSGNWEVIRILAYDETTQKIYFLSTEFSPRGRQLYSASTEGLLSRDCISCNFRKEDCTYFDASFSPMNQHFLLFCEGPKVPMVSLHSTDNPSNYYILERNSMMKETIQKKKLAKREIRILHIDDYELPLQLSFPKDFLEKNQYALLLIIDEEPGGQMVTEKFHVDWDSVLIDTDNVIVARFDGRGSGFQGLKVLQEIHRRTGSVEAKDQIAAIKYLLKQPYIDSKRLSIFGKGYGGYIASMILKSDEKFFKCGTVVAPISDMKLYASAFSERYLGMPSKEESTYQASSVLHNIHGLKEENLLIIHGTADTKVHFQHSAELIKHLIKAGVNYTLQVYPDEGYHISDKSKHHFYSTILRFFSDCLKEEVSVLPQEPEEDE
What is the function of this protein?
Promotes cell surface expression of the potassium channel KCND2.  Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:16123112, PubMed:19901547).  Has no dipeptidyl aminopeptidase activity (Probable).
What are the official names of this protein?
Inactive dipeptidyl peptidase 10, Dipeptidyl peptidase X, DPP X, Kv4 potassium channel auxiliary subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family. DPPIV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: NGF_MASNA
Sequence: MSMLFYTLITALLIGVQAEPYTDSNLPEGDSVPEAHWTKLQHSLDTALRRARSAPAAPIAARVTGQTRNITVDPRLFKKRKLRSPRVLFSTQPPPTSSDTLDLDFQAHGTISFNRTHRSKRSSTHPVFQMGEFSVCDSVSVWVGDKTTATDIKGNEVTVLGEVNINNSVFKQYFFETKCRARNPVESGCRGIDSKHWNSYCTTTHTFVKALTTDDRQAAWRFIRIDTACVCVLTRKAPRRG
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.  Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI.
What are the official names of this protein?
Beta-nerve growth factor, Beta-NGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RG68F_DROME
Sequence: MDAHSRFAPRLPGPAINPIVDNSDEPQPSLSDLHDFEPKLEFDDTELLAPSPLEKDVMVGDFVLAEDPELEPEEDVNPLEDDFEDQLREQSENFQTPRNKCDFLGTDKQGRHIFGIYASRFPEKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLDDKLNPSRKPSTPPPSSNINASRQQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDFVLQNHKDIYLIDVNQRTVSVD
What is the function of this protein?
Functions as a GTPase-activating protein (GAP) for RhoA/Rho1 during gastrulation by converting it to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 68F.
Protein: Y4CF_SINFN
Sequence: MAYDLAKISTTALMRPAFEAGIGFTRLDERIARSPVGSGWIERMHFLDACASLWIDGELVHLEDLVLHDATRDIRTPTHELTIARDVLRTRRRIAAQSPDWPLSTEGIRTLRQTSDINPVGVEAVEPADVIRPAVAIDPEGEGDDGNDAKDLPGVDYAAIDAVLARSEAAIEDARRPGRAGANSWAAEKDPLVYDLDWDEDARLVEWRSVLRQAQDLPAVLQAIVALDAWNELSVLQHAPWLGRLLCASILREAGITTGAHLAAINLGLKTIPVDRRRHRGRETRLLAIAHGLLAAAEIGMKEHDRLTLAKTMMDRKLDGRRTSSKLPELVELVMAKPLVSAGMVSKTLEVTPQAARRIVTELGLREMTGRGRFRAWGVI
What are the official names of this protein?
Uncharacterized protein y4cF.
Protein: NUDI_SALG2
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: HEXB_MOUSE
Sequence: MPQSPRSAPGLLLLQALVSLVSLALVAPARLQPALWPFPRSVQMFPRLLYISAEDFSIDHSPNSTAGPSCSLLQEAFRRYYNYVFGFYKRHHGPARFRAEPQLQKLLVSITLESECESFPSLSSDETYSLLVQEPVAVLKANSVWGALRGLETFSQLVYQDSFGTFTINESSIADSPRFPHRGILIDTSRHFLPVKTILKTLDAMAFNKFNVLHWHIVDDQSFPYQSTTFPELSNKGSYSLSHVYTPNDVRMVLEYARLRGIRVIPEFDTPGHTQSWGKGQKNLLTPCYNQKTKTQVFGPVDPTVNTTYAFFNTFFKEISSVFPDQFIHLGGDEVEFQCWASNPNIQGFMKRKGFGSDFRRLESFYIKKILEIISSLKKNSIVWQEVFDDKVELQPGTVVEVWKSEHYSYELKQVTGSGFPAILSAPWYLDLISYGQDWKNYYKVEPLNFEGSEKQKQLVIGGEACLWGEFVDATNLTPRLWPRASAVGERLWSPKTVTDLENAYKRLAVHRCRMVSRGIAAQPLYTGYCNYENKI
What is the function of this protein?
Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides.  The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide.  Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A.  During fertilization is responsible, at least in part, for the zona block to polyspermy.  Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida (PubMed:8253842).
What are the official names of this protein?
Beta-hexosaminidase subunit beta, Beta-N-acetylhexosaminidase subunit beta, Hexosaminidase subunit B, N-acetyl-beta-glucosaminidase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic vesicle, secretory vesicle, Cortical granule. Note=In oocytes, the enzyme is released from cortical granules after fertilization.
Protein: ALR_SHEPA
Sequence: MKPFPRAEISRHALKNNLARLHELAPSSKVMAVVKANGYGHGLLNVAQCLDNADGFGLARLEEALALRAGGVKAKLLLLEGFFRATDLVTLVEHDIETVVHHESQIEMLEQAELNKPVTVWMKVDSGMHRLGFVPDEFHQIYQRLLACDNIAKPINLMTHFACADEPDNDCTAKQIAVFEELTKDLLGDRTLANSAGALFWQQSQASWIRPGIALYGVSPVVGDLGTKHGLIPAMELVSQLIAIRDHKAGQPVGYGSHWVAEKDTKLGVVAIGYGDGYPRNAPLGTPVLINGRLAPIVGRVSMDMLTVDLGAGAKDNVGDKAVLWGKDLPVEEVAEHIGTIAYELVTKLTPRVAVCLD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: HIS8_CERS4
Sequence: MSDAIRPQPGILDIALYEGGKSHVAGIQNALKLSSNENPFGPSPKAKEAFLRSVHTLHRYPSTDHAGLRHAIAEVHGLDPARVICGVGSDEIITFLCQAYAGPHTDVVFTEHGFLMYRISALAVGANPVEVPERERTTDVDAILAACTPHTRLVFLANPNNPTGTMIGQADLARLAAGLPAQAILVLDGAYAEYVPGYDAGLALIEERGNVVMTRTFSKIYGLGGLRVGWGYGPKAIIDVLNRIRGPFNLSTTQLETAEAAVRDQDHVARCRADNARWRIWLAEALAEIGVPSDTSMANFILARFSDTEEAEACDLHLQTQGLIVRRVAGYKLPHCLRITIGDEASCRRVAHAIGQFKRMR
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: NDHK_NEPOL
Sequence: MVISSLSNSQPLNAPVSSSPITQELANNLILTTLNDLYNWARLSSLWPLLYGTSCCFIEFACLIGSRFDFDRFGLVPRSSPRQADLIITAGTVTMKMAPSLVRLYEQMPDPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAIIDAVIKLRKKVAQEQTAERRGIEQIHRYFTLSHRLQPVSPILTGQYLQAETRQAPPRELATGLDTLVPRSLEANYIERF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: TTCA_PASMU
Sequence: MTMTDTTQQDKKHTYNFNKLQKRLRRNVGNAIADFNMIEEGDKVMVCLSGGKDSYTLLDILLNLRLNAPIHFEIVAVNLDQKQPGFPEHILPEYLQSIGVDYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDMLETLFLNMFYGGKLKSMPPKLISDDGKQIVIRPLAYCKEKDIEKYAQAKHFPIIPCNLCGSQPNLQRQVVKEMLQKWDRQYPGRIETMFSAIQNIVPSHLCDTHLFNFKDLQRGQILENIEGDIAFDKPEFIATSPIDDDDEQQDFHQVELINVKEIH
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.