PharMolix/UniProtQA huggingface dataset:
Protein: E4PD_SHESM
Sequence: MIRVAINGYGRIGRSILRALYESGKRQQIQIVAINELAKPEAIVHLTQYDTTHGRFQPRVKLVDDQMLIGDDVIKILHEPDPAKLPWHEMDIDIVYEATGAILDRNSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNQDLLRAEHTVVSNASCTTNCIVPVIDVLDKHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPHMKDKFEAISVRVPTINVTAIDLSVTLDKTVDIATVNQVLELAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQTRVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKQS
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_DESPS
Sequence: MTETITFTLVKSGIGSTDKIRATLTGLGLTKLNKTVTRKDTPEIRGMLNKVKHLVRIDEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RNFB_SHEPW
Sequence: MSGIVIAIVVLTILALVFGVLLGFAAEKFKVEGNPLVDQVEALLPQTQCGQCGYPGCRPYAEAIANGDKINKCPPGGTATMEKIADLVGVDPEPLNATEAVQEKKVAFIREDECIGCTKCIQACPVDAILGSGKLMHTVITDYCTGCDLCVAPCPVDCIDMLPIEQTTKTWDWQLNAIPVKQVQEEPQC
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: DEOB_CLOBA
Sequence: MKKYNRIFTIVIDSLGIGGMPDSMEYGDKNVDTLGHIAESVEKFNIPNLEKLGIANLHPIKHVKEANKPLAHYMKMKEASVGKDTMTGHWEMMGLHITKPFQTFTDTGFPQELLDELTKRTGHNIVGNKSSSGTEILDELGEHQMETGDMIVYTSADSVLQICGHEETFGLDELYRCCEIARELTLKDEWKVGRVIARPYLGAKKGEFKRTSNRHDYALKPYGSTALNALKDNGFDVISVGKISDIFDGEGITESNKSKSSVHGMEQTLEIMDRDFKGLCFVNLVDFDALWGHRRNPVGYAEEIEKFDVNLGKVLEKLKEDDLLIITADHGNDPTYVGSDHTREFVPFIAYSPSMKENGLMDTVDSFATIGATIADNFELSMPENTIGKSVLEKLV
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP1A1_DICLA
Sequence: MVLMILPFIGSVSVSESLVALTTVCLVYLILKFFRTEIPEGLHRLPGPKPLPLIGNVLEVGNKPYLSLTAMSKRYGDVFRFRLGMRPSGCLSGSETVRKALIKQGDEFAGRPDLYSFRFINDGKSLAFSTDKAGVWRALRKLAYSALRSFSSLEESTPRDSCVLEEHSAKEGEYLYSNMLNAVMKVTGSFDPFRHIVVSVANVICGMCFGRRYGHNDQELLSLVNLSDPFGQVVGSGNPADFIPVLQFLPSTTMKNFMDINARFNKFVQKIVSEHYTTYDKDNIRDITDSLIDHCEDRKLDENANVQMSDEKIVGIVNDLFGAGFDTISTALSWSVMYLVAYPEIEERLYQELKENVGLDRTPLLCDRPNLPFLEAFILEIFRHSSFLPFTIPHCTSKDTSLNGYFIPKDTCVFINQWQINHDPELWKDPSSFNPDRFLSADGTELNKLEGEKVMVFGLGKRRCIGEVIARNGVFLFLAIIVQKLHFKTLPGEPLDMTPEYGLTMKHKRCHLRATMRASE
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: CD82_RAT
Sequence: MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILADKSSFISVLQTSSSSLQVGAYVFIGVGAITMLMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVEVLFYFNANKLKQEMGNTVMDIIQNYSVNASSSREEAWDYVQAQVKCCGWVSPSNWTRNPVLKNSTKTTYPCSCEKTKEEDNQLIVKKGFCESDNSTASENSPEDWPVHPEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLCRYIHSEDYSKVPKY
What is the function of this protein?
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
What are the official names of this protein?
CD82 antigen, Metastasis suppressor Kangai-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KATG2_MYCFO
Sequence: MAEAETHPPIGESQTEPAESGCPMRIKPPVEGGSNRDWWPNAVNLKILQKNPPAIDPSDEGYDSEAVKSLDVEAFQRDFDELLTNSQDWWPADFGHYGPLFVRMSWHAAGTYRVEDGRGGGGRGMQPFAPLNSWPDNVSLDKARRLLWPLKKKYGKQISWSDLIVYSGNRAMEHMGFKTAGFAFGRPDYWEPEEDIYWGAEAEWLGSQDRYAGANGDRTKLENPPXXPHMGLIYVNPEGPEGNPDYLAAAIDIRETFGRMAMNDIETAALIVGGHTFGKTHGATDIENGVEPEXXPLEQMGLGWANPGLGNDTVSSGLEVTWTQHPTKWDNSFLEILYSNEWELTKSPAGANQWKPKDNGWANSWPMAQGTGKTHPSMLTTDLSMRFDPIYGEITRRWLDHPEELAEEYAKAWFKLIHRDMGPVTRYLGPLVPKQTWLWQDIIPAGKQLSDADVATLKAAIADSGLSIQQLVNTAWKAAASYRSSDMRGGNGGRIRLQPQLGWEVNEPEELAPVIAKLEEIQAASDSGVSFADLVVLGGVVGLEKAIKAAGFDVAVPFTSGPRDALQEQTDVDSFAYLEPKGDGFRNFVAKGDSVPAEYRLIDRANLLGLSAPQMTVLIGGLRVLGANHGGSELGVLTDKVGQLTNDYFVNLTDMGTKWAPAPADDGTYVGTDRATGSPKWTASRVDLLFGSNSQLRALAEVYAEDDSKEKFVKDFVAAWTKVMNADRFDLEA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.  May play a role in the intracellular survival of mycobacteria (By similarity).
What are the official names of this protein?
Catalase-peroxidase 2, CP 2, Peroxidase/catalase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: METN_ECOL6
Sequence: MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGNVALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGELIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEVLGYV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RBM43_HUMAN
Sequence: MASVLNVKESKAPERTVVVAGLPVDLFSDQLLAVLVKSHFQDIKNEGGDVEDVIYPTRTKGVAYVIFKEKKVAENVIRQKKHWLARKTRHAELTVSLRVSHFGDKIFSSVNAILDLSVFGKEVTLETLVKDLKKKIPSLSFSPLKPNGRISVEGSFLAVKRLRESLLARACSLLEKDRNFTSEERKWNRQNPQRNLQRSNNSLASVRTLVPETARSGEMLVLDTDVFLYLKHKCGSYESTLKKFHILSQEKVDGEITTICLKSIQVGSQPNNAKHVKELIEEWSHALYLKLRKETFILEGKENREKRMIKRACEQLSSRYLEVLINLYRTHIDIIGSSSDTYLFKKGVMKLIGQKVS
What are the official names of this protein?
RNA-binding protein 43, RNA-binding motif protein 43.
Protein: NIRDL_PARDP
Sequence: MTMDDLDLRLLDGFQRDLPLEPRPFAAMATRLGTGEAEVIARLVRLRDEGIVSRIGATCRPNTAGASTLAALRVPAPRVDEIAALVGAEPGVNHSYLREGDWNLWFVATAPDTAALAESLVRIEAATGLAVLSLPLVRAFNIDLGFPLIGPRRAMALDRPADLDALRPRDKALMQALSSGLALVPRPFVALGQALHRSEAEVISRIRALAEARILTRVGVIVKHRALGWTQNAMVVWRLPEAAVEAAGTALAGVPGVTLCYQRRCVPGLWDWPLFCMIHARSHAEAMEVLAEARALPELQEVPHRILFSTRCFRQRGATIAEVAA
What is the function of this protein?
Involved in heme d1 biosynthesis.  Catalyzes the decarboxylation of siroheme into didecarboxysiroheme.
What are the official names of this protein?
Siroheme decarboxylase NirDL subunit.
What is the protein family that this protein belongs to?
Belongs to the Ahb/Nir family.
Protein: UVRB_ECO57
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity).
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPNE1_RAT
Sequence: MAHCVTLVQLSVSCDHLIDKDIGSKSDPLCVLLQDVGGAWAELCRTERVRNCSSPAFSKTLQIEYYFETVQKLRFGIYDIDNKTPELGDDDFLGGAECSLGQIVSSQTLTLPLMLKPGKPAGRGTITVSAQELKDSRVVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLAYRTEVVKNNLNPTWKRFSVSLQHFCGGDLNTPIQVRCSDYDSDGSHDLIGTFHTTLAQLQAVPAEFECIHPEKQQRKKSYKNSGTVCVKTCRVETEYSFLDYVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLTALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAQQRTASQYFVLLLLTDGAVTDVEATCKAVVEASKLPMSVIIVGVGGADFEVMEQLDADGGPLRTRSGEAAARDIVQFVPYRRFQNAPRETLAMTVLAEVPTQMVSYFKAQGWAPLKTLPAPAKGPAQAPQV
What is the function of this protein?
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes.  Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner.  Exhibits calcium-dependent phospholipid binding properties.  Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner.  May recruit target proteins to the cell membrane in a calcium-dependent manner.  May function in membrane trafficking.  Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit.  Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL.
What are the official names of this protein?
Copine-1, Copine I.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Note=Translocates to the cell membrane in a calcium-dependent manner.
Protein: RL32_ALCBS
Sequence: MAVQKNRKTRSKRGMRRSHDALPAAALTEDSNTGEVHRRHHISPDGMYRGRQVISQGDSDDE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ADDB_ALKMQ
Sequence: MAIRYIFGRAGRGKSYLALEEIKQKLQEEEDNKLFLLVPEQFTLQAERDLIRKQELTGMMRAEVLSFTRLAHRVFSEVGGLTRVPINELGKNMILRKIADESLKELSIYQSIAKQDGFITKLNELICEMKQHDITPTELTMELNEIEEETILKRKLEDITLLYQRFNNYLKGQYVDNEDHVNLLIENIERVEFLEGAEIWIDGFQSFTPQIIRVIEKLAQKVANITITFTMELNAKEKDKDLFHITQKTYLKVKTIAQKFNLDEEVINLDIEERKVLPKEKEIAHIEREFNTYPYKQYADEIANLEIFAGSNLYSEMENVAAQIIHLVRNRGYRWNDIALVSGGLDQYSMILKRVFEEYHIPYFIDEKRSIMNNPMIELILSSIEILSRGYQYEDVFSFLKTGFSDLTKDEVEQLENYVLQYGIRGKAYSEPFTKGFEKKQIQQKDKEEGEKQIDEEKKEKYNELRMRFIAPFAKFEKRIYRKKKIGEITKALFEFMKELNIEDKLNQWIEELREEKYFEYVNENTQIWNKIMEIFDQLTEILADESATLKEYGRILEAGFLACKVGVIPSTIDQVLVGSIERSKSHDIKALFVVGVNDGVLPFGQEDGGILLDHERESLVKKGISIGTTLESSLLEEQFMIYSAFSKPTEYLWVSYALADQEGKAMRQSILIDRFKKLFKNLRIKSDVVNDVDRQLHLITTPISTFKYMTENIRQNVDDKAMADMWWDVYDWYSKEPTWEDRRKLMVKGLFHQNQITYIGENKAKSLYDNPIKSSVSRLERFANCPFSHFVTYGLRPKERKEYQLSNPDIGRLFHDSMEQFTKEMVNEEIQWKDLTKEKNDELVEKVIDEMVPDFEHGIMLSTHRYQYLVTRLKRISKRAMWTLTDHVKKGEFVPMGHEIIFGLEGDVPPIIIELANGEKIYLEGRIDRVDLLNDEEDGNYVKIIDYKSGSKEFSLSDVYYGLQIQLMVYLDAILSSEEKKHQVEIHPGGIFYFKIDDPMVKTTEKVVEEVEKEINKKLKMKGLVLKDVNIIKKMDRSIGRSSTIVPAGLTKDDEISKSSSALPEEDFKALLNHVRRLVKEIGEEMLKGNVKIEPFKKGGDTSCKYCDYIAICQFDNSFHDNQYKNIKELKSDEVLERIKKESQKKLE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: YABA_STRP3
Sequence: MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLENTKLRERLSHLEHETAAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRELLDRK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: YBEY_MYCTU
Sequence: MSIEVANESGIDVSEAELVSVARFVIAKMDVNPCAELSMLLLDTAAMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPSMLGDIVLCPEFAAEQAAAAGHSLGHELALLTIHGVLHLLGYDHAEPDEEKEMFALQDRLLEEWVADQVEAYQHDRQDEKDRRLLDKSRYFDL
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGLF_EMENI
Sequence: MAHRWLILALVAAAAPRALASPGPSLNERQSDDEPFSPPYYPAPNGGWVSTWAEAYEKAHSIVSNLTLAEKVNLTTGTGIFMGPCAGQTGSVPRLGIPNLCLHDSPLGVRNTDHNTAFPPGITVGATFDKSLMYERGVGLGEEARGKGVNVLLGPSVGPLGRKPRGGRNWEGFGFDPVLQGIGGAETIKGMQSTGLIACIKHFVGNEQEMHRMSSVVTQGYSSNIDDRTLHELYIWPFAEGVRAEVGSVMIAYNDVNKSSCSQNSKLINGVLKDELGFQGFVVTDWLAHYGGVSSALAGLDMDMPGDGAVPLFGNSYWGPELSRSILNGTVPVERLNDMVTRILATWYKMGQDQDYPLPNFSSNTEDEKGLLYPGAVISPIGVVNQYVNVQGNHNITARAIARDAITLLKNEGDLLPLRRNDSLKVFGTDAGPDPQGLNSCADKGCNRGVLTMGWGSGTSKLPYLITPQEAIANITPTAEFFITDSFPSSVDANDEDIAIVFINSDSGENYITVDGNPGDRKTSGLHAWHNGDELVKAAAERFSQVVVVIHTVGPIILEEWIDLDSVKAVLIAHLPGQEAGYSLTDVLFGDYSPSGHLPYTIPYQESNYPSSVGLLQQPFGQIQDYYTEGLYIDYRHFLKEDITPRYAFGHGLSYTTFEFSEPALSVVTPLDSAYPPSRPAKGPTPTYPNTIPPASEAAWPAKFNRIWRYIYPYLNNPQADAAVANSSKTYPYPDGYSTDPQPPPRAGGAEGGNPALWDVAFSVQVTVTNTGQHSGRAVAQLYVELPDSLGLDTPSRQLRQFEKTKVLETGQSETLTLEVTRKDVSVWDVEVQDWKTVVGGEGVKIHIGESVLDIRTECEVGGRCVTL
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase F, Beta-D-glucoside glucohydrolase F, Cellobiase F, Gentiobiase F.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL5_SOLME
Sequence: SSKDSKQLDAEVHRKYIYGGHVAAYMNILMEDEPEKYQSHFSSYIKADLAPDNIEEMYKKVHAAIRPDPSPKKSQKQPPKTHKRYNLKKLTYEERKAKLIERLNALNAAGGNDDDDEEDDE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KTHY_DECAR
Sequence: MKGKFITFEGIDGAGKSSHVEWLAGLLRQRGIVVHVTREPGGTELGEKLRELLLNEPMHLETETLLMFAARREHLARLIEPALARGEWVVCDRFSDATYAYQGGGRGLDRAKFLALEHWVHGHLQPDLTLLFDLPLDVARERIVLANRVLDKFEQERVDFHERVRQAYLERAHTSPSRIRVIDANQSIENIRKQLEQIVSTDCL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: Y1591_STRP6
Sequence: MMNMQNMMRQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFTGDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein M6_Spy1591.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL14_THEKO
Sequence: MAKKGAGATRGISPVRPTRALPIGAYLKVADNSGAKVIQIIGVVGYKGTRRRLAAAGVGDMVVATVKKGRPDMRHQVVRAVVVRQRKEYRRLDGMRVKFEDNAAAIVTPEGVPRGTEIRGAIAREAAERWVRLGSIASIVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RUVB_NOCSJ
Sequence: MTFHEEDLDQAEEVHVRSLTAAEADGDERAVEAALRPRTLDEVVGQVRVRDQLGLVLEAARRRGRAPDHVLLSGPPGLGKTTLAMIIASEMGAPLRLTSGPAITHAGDLAAILSGMNEGDVLFVDEIHRMSRPAEEMLYMAMEDFRVDVVIGKGPGATAIPLEIPPFTLVGATTRAGLLPGPLRDRFGFTAHLEFYEPDELDLIVQRSARLLDVHVLPDGTAEIASRSRGTPRIANRLLRRVRDFAQVRADGVVTLPVAQDALDLYEVDQLGLDRLDRGVLDVLCRRFGGGPVGISTLAVAVGEERETVEEVAEPFLVRNGFLARTPRGRVATPAAWEHLGLTAPPTLTLPESDPPLFED
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PSBU_SYNE7
Sequence: MKQLAQRLFSLALVLALVLGISVQSAQALSLQSPLLAVAEAEIRNEADAQRIEAGGKLDLNNIGVRAFQQFPGMYPYLASKIVLGGPYDSVDDVLKLDLSDRQREVFEQYKENFTVTPPRDALNEGDDRINNGIYR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: BCAM_RAT
Sequence: MEPPDARAGLLWLTLLLSGYSGAQAELHVSVPPRVEVMRGEQIALDCTPREHPENYVLEWLLVDASGARHRLASVEPQGSEFLGTIHNSRGRRPPYKIDSLGRLVIAEAQVGDERDYVCVVKAGAAGTSEATSSVRVFATPEATEVAPNKGTLSVMEQFAQEIATCSSNNGNPVPRITWYQNGQRLDVPMELNSKGYMTSRTVREASGLYSLTSTLYLRLHKEDRDASFHCAAHYDLPSGQHGRLDSHTFRLTLHYPTEHVEFWVGSPSTTEGWVREGDAVQLLCQGDGSPSPEYSFFREQGNQEEQLNVNLKGNLTLEGVHRSQSGIYGCRVEDYDADEEVQLVKKLKLHVAYLDPLELSVPEEFSVFLNSSGTVVNCSARGLPAPIVRWTKDSVTVADGPILSLDSVTFDSAGTYTCEASTPTVPLLSRTQSFQLVVQGAPELKPNEIKPKSGTSWTEGDEVMLTCSARGFPEPKLTWSQRGDTTPAEPPFEGRGWMSSSLTLKVTSALSREGVSCEASNIHGKNGHVFHFGSVAPQTAQAGVAVMAVAVSVGLLLLVVAAFYCMRRKGRPGCCQRAEKGAPPAREPELSHSGSERPEHTGLLMGGPSGGGRGGNGGFGDEC
What is the function of this protein?
Laminin alpha-5 receptor.  May mediate intracellular signaling (By similarity).
What are the official names of this protein?
Basal cell adhesion molecule, B-CAM cell surface glycoprotein, Lutheran antigen.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: KITH_HUMAN
Sequence: MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
What is the function of this protein?
Cell-cycle-regulated enzyme of importance in nucleotide metabolism (PubMed:9575153).  Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate (PubMed:22385435).  Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable).  Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c-azido-3c-deoxythymidine (AZT) (PubMed:22385435).
What are the official names of this protein?
Thymidine kinase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_ACICJ
Sequence: MADGGLIGLYPGTFDPITNGHLDIIGRAAQLCSKLVIGVARNAGKGPLFPTAERVEMVRAEIAPIAERTGTEIDVQAFDSLLIAFAQQVSAQVIVRGLRAVSDFDYEFQMAGMNARLDQRIETIFLMASERHQFISSRFVKEIAQLGGDISSFVPKLTLERTLRRVGRP
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOSSC_DROMO
Sequence: MAFPTSSAQQAETNRKILEEIQTKKQLLIGLGSTANQMPAPQLLGQPTVTAEFVQNVSATPNAAGGIAAPRSAFNPTSSTTLGFFIPQDSYFGNSFIPVLPRLEPVPTPPAPNSK
What are the official names of this protein?
SOSS complex subunit C homolog.
What is the protein family that this protein belongs to?
Belongs to the SOSS-C family.