PharMolix/UniProtQA huggingface dataset:
Protein: RGS9_TAMST
Sequence: MTIRHQGQQYRPRMAFLQKIEALVKDMQNPDTGVKTQSQRVLVTSVPHAMTGGDVLQWIIQRLWISSLEAQNLGNFIVKYGYIYPLQDPKNLILKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYNFLNKKINYKWDFVIMQAKEQYRAGKERNKADRYALDCQEKAYWLVHRCPPGMNDVLDYGLDRVTNPNEVKKQTITAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQETTKKSSTLPFIRRHLRSSPSPVILRQLEEEAKAREAANTVDITQVMSKLDRRSLLKKELPPK
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to G(t)-alpha.  Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 9, RGS9.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Targeted to the membrane via its interaction with RGS9BP.
Protein: PPAC_LACAC
Sequence: MEKEFVFGHQNPDTDAIGTAIAFSYLQNKLGYNTEAVALGEPNDETAYALKKFGFEAPRVIKEAAPEVDSVMLVDHNEPQQSVSDIDKVKVTHVVDHHRIMNFNTADPLYYRAEPVGCTSTIVWKMFNENDIEIPEKIAGIMLSAIISDTLLLKSPTTTDDDKEAVEALAKIAGVDYKDYGLAMLKAGTNINDKSEEELIDLDAKSFELNGHNVRVAQINVVDLPEALERKDAFLKAMEKASNDNDYDMFMLLITNILDSDSEALVVGSDETKSFFEKAFDKKLDDSEVKLPGVVSRKKQVVPPLTDAFNA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADB_CITK8
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGQALDVLEKQTDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTLSAINGYALGGGCECVLATDYRLVTPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDIGAEQALKIGLVDGVVKPEKLLDGAIAVLRQAIDGSLDWKAKRQPKLEPLKLSKIEAAMSFTIAKGMVAQTAGKHYPAPMIAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQFVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVIMKDINDKSLTLGMTEAAKLLNKQLERGRIDGLKLAGVISTIHPTLNYAGFDRVDVVVEAVVENPKVKKAVLAETEDNVRPDTVLASNTSTIPISELASALKRPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKVDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDASRYGQKNGLGFWRYKEDSKGKPKKEEDAAVDSLLAEVSQPKRDFSDEEIIARMMIPMVNEVVRCLEEGIIASPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: TEN1_SCHPO
Sequence: MDSAKLIFINQINDCKDGQKLRFLGCVQSYKNGILRLIDGSSSVTCDVTVVLPDVSIQKHEWLNIVGRKRQDGIVDVLLIRSAVGINLPRYRQMVSERQKCD
What is the function of this protein?
Required for telomere maintenance.
What are the official names of this protein?
Protein ten1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RL16_METSB
Sequence: MLQPKRTKFRKAFKGRIHGAAKGGFELSFGQFGLKALEPERITARQIEAARRAMTRHMKRAGRVWIRIFPDVPVSKKPTEVRMGKGKGAPELWAVRVAPGRIMFELDGVPVDLAREALQLASAKLPIKTRFIQRIQE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CART_RAT
Sequence: MESSRLRLLPVLGAALLLLLPLLGAGAQEDAELQPRALDIYSAVDDASHEKELPRRQLRAPGAVLQIEALQEVLKKLKSKRIPIYEKKYGQVPMCDAGEQCAVRKGARIGKLCDCPRGTSCNSFLLKCL
What is the function of this protein?
Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus.
What are the official names of this protein?
Cocaine- and amphetamine-regulated transcript protein.
What is the protein family that this protein belongs to?
Belongs to the CART family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_LIMRD
Sequence: MIQTIDLKKGMVFERDGKLLKVLQINHHKPGKGNTLMQMDIQDLRSGSIVHTTMRPSEKVEQVNVDKRSAQYLYDEGDSAVFMDLESYEQYSLNHDLLGDDKNYLVENMKVILNFVNGDIIGVELPTTVELTVAETEPMIKGATIDGGGKPATMETGLVVNVPAFIKNGDKLIINTTDGSYKSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM11_DEBHA
Sequence: MSAEPSQFNKLLTKYDFKLASASEEYRNRRKRQMMLFMGSAAITIFTSRLAYKSTITRQYVPSLFQGNHAPPLSYNFTSDAAVAVGTGTLLCGSVSSMVIFGTCWIIDVSNFQEFGWKMKSLMGGYEKQKELAKLPMDEESAFLQDSLNDILDGKYDFDETTPAEK
What are the official names of this protein?
Altered inheritance of mitochondria protein 11.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNLJ_CORU7
Sequence: MSTQYDSDSSPAASNSGSADPALAELAQQWQSLADQVRHHREVYYYGNPEISDAEFDALLTRLQEFENSHPEAVTGPSPTTEVAPSPPESSPFRNVDHQEPMLSLDNVFDTEQLSSWLDRTPAKTYLTELKIDGASINLLYRNGVLELALTRGDGTTGEDITHNARTLSDIPARLQPSEDFPVPEIVEIRGEVFIRVEDFAKMNAQRQAEGQKMFANPRNAAAGAMRQKDPAETARRPLRLICHGIGAREGFTPASQHAAYEALAAWGLPVSPYTKQVHSAKEVLEQVAYWADHRHDADHEMDGLVIKVDDTESQQRLGTTSRAPRWAIAYKYPPEEARTRLHDIRLGIGRTGRATPYAVMEPKYVAGSTVTMATLHNPSEAHRKGVRLGDEIMIRKAGEVIPEVLGPVEDARNGAEREFLFSSLCPECGTPLAPARGDDADWRCPNTRYCPGQLHTRLTYIAGRGAFDIDALGEKAAYDLIHSGVLPDETGLFSLTEEDLRRTDAYTTKSGALNKQGETLLTTLAAAKEVDLWRVIVALSIRHVGPTAAKALANHYGSIPDVAAADVETMSTVDGVGPIIAESVRDWFAVSWHQEIVDAWAAAGVRMEQDVTEQPSADAAGSIQADLLAGLSIVVTGTLEDFDRSSAKEAIESRGGKATGSVSKKTDYLVAGAKAGSKLTKAEELGIPVLDEAGFHKLLSEGPGKGDAEED
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: YAOG_SCHPO
Sequence: MTTLKVDEDLECALMEQFIEALHQRCTDIPRTQLCVLAISFNRFILHKSPDIFTYIQYYQQKLNSYGFPLPPVVLKSLQMPLTSPEPDADERFRDGDTEFDTAGVTASSCFPVDVKSPSVRAFGNVTFQSD
What are the official names of this protein?
Uncharacterized protein C11D3.16c.
Protein: WAC_XENTR
Sequence: MVMYARKQARLSDGCHDRRDSQPYQTLKYSSKSHPSSSDHRHDKMRDSTDPSPPNKMRRSNSPENKYIDSAGHGKAKSMHLHRVRERDGGTSFSPQENSHNHSAIHSSNSHSSTPSKTSDSAYDPADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKETSKVAVNSFPKDRDYRREAMQAAAAVEEKHSSDTSTMLPQNILSQTSRHNDRDYRLPRTDSHSSAAPVQQPVKAAVHPAAAPSTVPSSPFTVQPDHPPPKKSYDANGAALSKLPTPTSSIPVPKSERKETASSDKSSCTTPSTSSAPGLNLSAAPPSSSSSTVPVSPVPQSPIPPILQDPNLLRQLLPALQATLQLNNSNVDISKINEAAVTQASLQSILHKILTAGPSAFNITSLISQVAQLSAQAAQSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPHKPLLSTPPVTSQPKVGTPGSKQGSSAQTASQQSSAADKSQGHEPTSPRNLQRSSSQRSPSPGPNHNSSTCASSTSAPQNSSARSSCSLTPTLAAYFNENLVKHVQGWPADHAEKQASRLREEAHNMGSIHMSEVCTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
What is the function of this protein?
Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1).  Positive regulator of amino acid starvation-induced autophagy.  Positively regulates MTOR activity.  May negatively regulate the ubiquitin proteasome pathway.
What are the official names of this protein?
WW domain-containing adapter protein with coiled-coil.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTL_CLOB6
Sequence: MRKINLLDLETTNKIAAGEVIERPFSVVKELVENSIDAGAKNITIEIEDGGQKLIKIIDDGEGIYPIDIKNAFLPHATSKINSIEDIYKISTMGFRGEALASISSVSKTKLKSRVDSYNFGKEIYIEGGKIEYLKDTGCNVGTTIEVSDLFYNVPARLKFLKSARSDSSAISDIVNRFILAHPDISFNLINKGKQSIKSYGTGNLKDSIRCVYNKTISENLINFENHKDIISVYGFIGKPEISRKSRTNQSIFVNKRYVKSKFITAAVENAFKSFLTVNSYPFFVIFIDIFPEYIDVNVHPTKSEVKFKDERAMFKTIFDAVHEAIKGELKESFTNFFNKEDINIYDSEKSIAETIKPGKEEVQIPIDLNSNNKIDIFGNNINKLPNNTELLKNIDIKEKNILENNDNFYTSNQNEIYYTNKNDKCLNSCNKDDYSKIEKPLQKDNKNLDNLYLNEHNTNSSSINIKENKPNNFYVDMKIIGQFNNTYILIEKDKELYIIDQHAAHEKVLFEKFKSEIEKGYVVSQILLSPVVIELSEDEFNIYEENKDIFKNSGFSVEAFGECTINIKEVPLILGKPNVENLFMDILYNLKNMKSKETSTIKYNAIATLACKSAVKANDNLKEEEIKKLIEDMLILNNPYTCPHGRPTMIKFTLKDLEKKFKRIQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DMT1A_XENLA
Sequence: MQNNEEPYSKTRNSGQHPSGVHTKKSPRLPKCARCRNHGYASPLKGHKRYCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGISHPIHLPIAAELLIKKEHGGSSSCLMLENSSTQTTSTPTSGSTASSEGKVLIQEIPSITSRGHMESTSDLVMDSPYYSNFYQPPLYPYYNNLYNYPPYQMAMAAESTSGNDMGGISGPPLKNNHRNHPAAYVPSQSGNQWQMKNRENRFPGHSGSSQFRMHSYYPPYLGQSVPNPACVPPFLTFEEIPSYSEAKASVLSPPSSQDSGVISLSSNSPVSNESTKAVAEQEPNSESSLFTVTTAAENGE
What is the function of this protein?
Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and germ cell proliferation.  Acts both as a transcription repressor and activator.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor 1A, xDmrt1, DMRT1-alpha.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIRP_LOCMI
Sequence: MWKLCLRLLAVLAVCLSTATQAQSDLFLLSPKRSGAPQPVARYCGEKLSNALKLVCRGNYNTMFKKASQDVSDSESEDNYWSGQSADEAAEAAAAALPPYPILARPSAGGLLTGAVFRRRTRGVFDECCRKSCSISELQTYCGRR
What are the official names of this protein?
LIRP, Locusta insulin-related peptide.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAF16_YEAST
Sequence: MVSQFAIEVRNLTYKFKESSDPSVVDINLQIPWNTRSLVVGANGAGKSTLLKLLSGKHLCLDGKILVNGLDPFSPLSMNQVDDDESVEDSTNYQTTTYLGTEWCHMSIINRDIGVLELLKSIGFDHFRERGERLVRILDIDVRWRMHRLSDGQKRRVQLAMGLLKPWRVLLLDEVTVDLDVIARARLLEFLKWETETRRCSVVYATHIFDGLAKWPNQVYHMKSGKIVDNLDYQKDVEFSEVVNAKVNGQVAFENDNNKVVISKVNSLHPLALEWLKRDNQIPDKEIGI
What are the official names of this protein?
CCR4-associated factor 16.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BSAZ_BURP0
Sequence: MAEKTEKPTAKKLRDAAKKGQTFKARDIVALIVIATGALAAPALVDLTRIAAEFVRIASTGAQPNPGAYAFAWAKLFLRIAAPFVLLCAAAGALPSLVQSRFTLAVESIRFDLTALDPVKGMKRLFSWRSAKDAVKALLYVGVFALTVRVFADLYHADVFGLFRARPALLGHMWIVLTVRLVLLFLLCALPVLILDAAVEYFLYHRELKMDKHEVKQEYKESEGNHEIKSKRREIHQELLSEEIKANVEQSDFIVANPTHIAIGVYVNPDIVPIPFVSVRETNARALAVIRHAEACGVPVVRNVALARSIYRNSPRRYSFVSHDDIDGVMRVLIWLGEVEAANRGGPPPETRAPTSAEPQARDGVAPPGDACADNAFPDDAPPGAAAPNAGSPDSPAPDGGAPARTGDQNA
What is the function of this protein?
Part of the bsa type III secretion system, is involved in the intracellular replication of invading bacteria inside the host cell.  Probably necessary for the lysis of the vacuole membrane and escape into the host cell cytoplasm (By similarity).
What are the official names of this protein?
Secretion apparatus protein BsaZ.
What is the protein family that this protein belongs to?
Belongs to the type III secretion exporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YOP1_CRYNB
Sequence: MAAHSEQIKNNFLNNPYAQQVFNIANGQVSALDAELNKYPILRQLEQQTKVPKAYGVIALGFSSVLLIFFNMFGLAQPISNLIGWALPAYLSILAIESPQTNDDKQWLTYWVVFGSLNLVESMGLRAVLYWVPMYFVFKTLFTIWLMLPATRGAEILYFHFLRPMVGNVKSRSQSSFGTSDPLAKETGFNPAGTTAPSSFAHEKTL
What is the function of this protein?
Required to generate and maintain the structure of the tubular endoplasmic reticulum network and the vacuole.  Induces high curvature in membranes and causes membrane tubule formation.  Involved in membrane/vesicle trafficking.
What are the official names of this protein?
Protein YOP1.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: EL2B_HORSE
Sequence: IVGGRPARPHAWPFMASLQRRGGHFCGATLIMGWGQLGTNRPLPSVLQELNVTVVTAGICFGDSGGPLVCNGL
What is the function of this protein?
May be involved in the degradation of connective tissue in chronic lung disease.
What are the official names of this protein?
Neutrophil elastase 2B, Proteinase 2B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
Protein: LOLD_TREDE
Sequence: MSKDIVLISGLTKTFSSASEKLVIFDKLNFSIEEGKKISITGESGSGKSTFLNILGGLESADSGEIIAGSYKVHSLDEKSLTEYRSSFLGLVFQFHYLLKDFTALENVMLPALIAGRSKKEIKEKALSLLEDVKLAERKNHFPSQLSGGERQRVAVARSLINSPSLILADEPTGNLDPANAETVQNLLFSVVDKHKKTLVLVTHDQNIASMTDISYKLYKGNLEEV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ELTD_MYCS2
Sequence: MSNQVPEKMQAVVCHGPHDYRLEEVAVPQRKPGEALIRVEAVGICASDLKCYHGAAKFWGDENRPAWAETMVIPGHEFVGRVVELDDEAAQRWGIAVGDRVVSEQIVPCWECLFCKRGQYHMCQPHDLYGFKRRTPGAMASYMVYPAEALVHKVSPDIPAQHAAFAEPLSCSLHAVERAQITFEDTVVVAGCGPIGLGMIAGAKAKSPMRVIALDMAPDKLKLAEKCGADLTINIAEQDAEKIIKDLTGGYGADVYIEGTGHTSAVPQGLNLLRKLGRYVEYGVFGSDVTVDWSIISDDKELDVLGAHLGPYCWPAAIKMIESGALPMDEICTHQFPLTEFQKGLDLVASGKESVKVSLIPA
What is the function of this protein?
Catalyzes the NAD-dependent reversible oxidation of erythritol and L-threitol.  Involved in the degradation pathways of erythritol and L-threitol, that allow M. smegmatis to grow on these compounds as the sole carbon source.
What are the official names of this protein?
Erythritol/L-threitol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RL6_SHEHH
Sequence: MSRVAKAPVAIPAGVEVTLNEQTITVKGTKGSLTRVINSDVSVVVEDNEIKCSPVESAKTAAQAGTARALINNMVVGVTEGFVKKLTLVGVGYRAKLAGKDIDLTLGFSHPLVHKLPDGVTAECPSQTEIVLSGTDKQLIGQVAAEIRGYRPPEPYKGKGVRYADEQVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RSMG_SYNP6
Sequence: MTSGFALDVRNWTETLGWQPSPQQQQQFEALYHGIIAGNQRLNLTRITDPAEFTEKHLWDSLYGLRPLLTDDWSGEIIDIGTGGGFPGLPAAIALTKSRVMLLDSTRKKIQFLQTLAQELGLSNVTVAVGRAEEWGRDRRQRARYDWATIRAVGPATVCAEYCLPLLKIGGKAVLYRGQWTEEEAIALDRAVTILGGEVVDVSATFLPESGAERHCITLQKTAQTPAAYPRMVGLPSQKPLG
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_ACIB5
Sequence: MSFEQKPKVTVILANLGTPDEATVPAVRRFLKQFLSDPRVIEIPKFIWWIILNLFVLPFRPKRVAHAYASVWSTDSPMREIVFEQTQRVQAYLERENKQFDLTVLPAMTYGNPGIDAVLEKLATNPQEHVILLPLFPQYSATSTAPLYDAFAKWIPTQRNLPGLTIIKDYYQHPMFIQALAESVLAYQEQHGKPEKLLMSFHGIPQPYADKGDPYADRCRITAKLVAEALHLKDDEWAISFQSRFGKQEWVKPYTDQLLQDWAKQGVKSVQVLSPAFSADCLETLEELAIQNAELFQQAGGGSYAYIPALNSDQAHIDLLAGLVQANLDALTHTLAHR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSPC2_DICD3
Sequence: MNISKLPPLSPSVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVTLNDFTLFGVSPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVNEEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPGAQVNEQLQQRASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDIYMEFGGDE
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.  Required for the translocation of the multiple pectic enzymes.
What are the official names of this protein?
Type II secretion system protein C, T2SS protein C, General secretion pathway protein C, Pectic enzymes secretion protein OutC.
What is the protein family that this protein belongs to?
Belongs to the GSP C family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: Y007_BORBU
Sequence: MNERENIIALIFDFDNTLIYGNMQQVLFDEYCVDSCSFWREVEGLEYVYKQNGYNIISNEMIYLSHFLTYVREGFFESLDNRALFNLGAKLRFFEGVIGLFDEISEINKKLENSKSQIKIYIVSSGFRQMILGSKIAPYVSKVWACEFIDSYLMPFYELRDDKFSKNKILSSVCYFVDHTIKTRVIFEINKGSYEKINERVPKSKRQIPFKNIFYIADGFSDVPAFEILNNILKHCRNTLTVYHGNDKNAKKLFYENRVGDFAEANYTKGTKLYNWIMEKICLSV
What are the official names of this protein?
Uncharacterized protein BB_0007.
Protein: LEXA_BACCQ
Sequence: MEKLTKRQQDILDFIKLKVQEKGYPPSVREIGQAVGLASSSTVHGHLSRLEEKGYIRRDPTKPRAIEILGEDRMDTETQSVIQVPIVGKVTAGLPITAVESVEEHFPLPASIVAGADQVFMLRISGDSMIEAGIFDGDLVVVRQQQSAYNGEIVVALTEDNEATVKRFYKEKDHFRLQPENSSLEPIILKQVSVIGKVIGVYRDLH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL3_BACSU
Sequence: MTKGILGRKIGMTQVFAENGDLIPVTVIEAAPNVVLQKKTAENDGYEAIQLGFDDKREKLSNKPEKGHVAKAETAPKRFVKELRGVEMDAYEVGQEVKVEIFSAGEIVDVTGVSKGKGFQGAIKRHGQSRGPMSHGSRYHRRPGSMGPVDPNRVFKGKLLPGRMGGEQITVQNLEIVKVDAERNLLLIKGNVPGAKKSLITVKSAVKSK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity).  Strongly stimulates 23S rRNA precursor processing by mini-ribonuclease 3 (MrnC); 20-30% DMSO can replace L3, suggesting the protein may alter rRNA conformation.
What are the official names of this protein?
50S ribosomal protein L3, BL3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MCE_WTV
Sequence: MAIDSYCIPNFSQTIDNRTIVNIFQSCKYRSQLSVCFLNDKSAADKFSNSMRQGSGTITFIIHAEDGEISEQLHSTFRSVSTMLLCGMQLFVFIVAPRNVISSETGKAITWAFRGSFIELRDHGRGEQALHDILEQFYRLSPLVNVPKMGMAYYGPTSFAELLSLSSKNKTSWRYVIDYSMFTRSALVGFASHMMDECSFANKQINVIGYNPPYVWAGLRHGVTTRFTEMSTPDPEGYGPIKLILPRLTGNVLLKKVKYVQHDPQKKLLCDDSVMFALSRNILYIGVYPATHLLDYNLKGWRMVAVDPKINAAWAETLKQRTSIDLVPISAKFEFNAQSTRDIVLKYFSGVPFSIIDDSWVEGTEDYEKFQELKQSYFEQLVMNGSTSKLRVSMISMKWNRTKDVKCRRLLALLPQPYGGSLRELRAYFHVNGAAEVNIKKSEVNSYMDKFTSLSISEQIGSQKFMHMLITNYGDALKLKTGRDKAIIASYSLSNAINKKERVLKFLSDAAKSETLIIFGAPNLNRVKFMIKSGIVLGSDVTISNDLITFKNASGKVWKDYGYTQSELIKSSMIEITIEQMLCISSSSYNGVGYFANSIYNDMFSWYVPEWLFEKYFSIQDIRLSPVALVKCFTTSIRNLCYVPHLTYYALRGSFVEKVLITNNVLNSSYLITGTSHSTFKVLSNFEVPSPAGVLKFKAGDDVNISGHLLSLVIAAHFVASPTLLWATHMKRMTTPVNLPKNLDKLLFFDNKIKNGMLEKWHSREEVVLAAMIVENYVAHILNGRHSIEIIQEITQVIYEKFNA
What is the function of this protein?
Enzyme involved in mRNA capping (Potential).  Binds to GTP and might have guanylyltransferase activity.  Together with the RNA-directed RNA polymerase P1 and protein P7, forms an transcriptional complex positioned near the channels situated at each of the five-fold vertices of the core (By similarity).
What are the official names of this protein?
Putative mRNA-capping enzyme P5, Structural protein 5, mRNA guanylyltransferase P5.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus protein P5 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Located inside the inner capsid. Found in the interior of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: GLMU_TRIL1
Sequence: MAISAALILAAGKGTRMKSALVKVLHELAGRPMLGWPLAAAREAGAGQIVIVAGHQADQVQKRFGADAGIRIALQEEQLGTGHAVSCSLDQLDGLSGAVLILCGDTPLLTAATLQRLAAEHAASGAAVTVLTAKLDRPFGYGRIVRDSEGRVRRIVEQKDASPEEQAIDEVNSGIYCMELEFLRSHIGRLGSENAQNEYYLTDLVGIAVAEHAGCSAVVADDPDEIMGVNDRVQLAHAARVLRQRVNLQLMLAGVTLIDPDQTYIDADVQVGNDTIIWPGCVLRGATSIGSGCTLENNVRVSDCVIADRVQLKAGSVLSEAQVAEDVSVGPMAHLRPGSVLQAQVKIGNFVETKKVVMGTGSKASHLTYLGDAEIGSDVNIGCGTITCNYDGRHKHKTVIGDGVFVGSDVQLVAPVTVGANALIAAGTTVTQDVPPDSLAIARTPQVNKTGWCLKKRDNG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_EXIS2
Sequence: MFKFNEEKGQLKCSFCGKTQEQVRKLVAGPGVYICDECIELCNEIVEEELGTEEEVELKNVPKPHEIRATLNDYVIGQEKAKKSLSVAMYNHYKRINAGGRADDVELSKSNIVMIGPTGSGKTLLAQTMARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIDQSIKRRLGKKVIGFGNDSENRNLTQKEILAAALPEDLQKFGLIPEFIGRLPVMATLEPLDEEALVQILTKPKNALVKQYKKMLQLDDVELDFTEDALVEIAKLAIERKTGARGLRSIIEETMLDIMFEIPSREDIAKVIITAETLTGKRGPTLELKDGTIEHGKEKETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.