PharMolix/UniProtQA huggingface dataset:
Protein: VERG_PENPO
Sequence: MAICIYEHDAAKIIPTLVSELPYSTTLLRRIQHGIAYPYETAHILATFPPGLTPEPGQPWLAARVDLFAGRTTQMIIYSSLEAEHTSIPPIVTVSDSTEILNVDSTSNNSKNNDTNDADNPDINSITKFIVSTFSASPPVLALARAQLLALLEYVKTNMLPFYLSYLAKSAQATSVAAETPPVSTSSVTSNNTSPTSVPLIPAPDPQAFLIGSLHTGLFSLLQQSGSYTLSNPIPNIRVHRFDDPPYYKYFFRRSEFSPEAVCGRSADLPFADLSLPSGYRFHDREGREGVLSKHLDLVQSRTHIPRPRAQLSKIPGMAVYLDSTSSDADEMPIAWGFLGVDGALVTLHVEPEHRGRGLAVPLSKAIMRRGMAVDGVFGAGSVNSEDSQTRERVGAWAHTEVAGYNNASRRVMEKIGGQVLTTVTWTVIELLD
What is the function of this protein?
Acyl-CoA N-acyltransferase; part of the gene cluster that mediates the biosynthesis of the neurotoxin verrucosidin, a methylated alpha-pyrone polyketide that inhibits oxidative phosphorylation in mitochondria and thereby causes neurological diseases (PubMed:34093475).  The carbon backbone of verrucosidin is synthesized by the HR-PKS verA, and further modified by the other verrucodidin cluster enzymes (Probable).
What are the official names of this protein?
Acyl-CoA N-acyltransferase verG, Cluster 4 protein G, Verrucosidin biosynthesis cluster protein G.
Protein: REX_CLOPE
Sequence: MEKKKGISMAVIKRLPKYHRYLQELMENDVDRISSKELSEKIGFTASQIRQDLNCFGDFGQQGYGYNVKELYNNIGSILGLTRDYNTVIIGAGNIGQAIANYNSFNRLGFKLKGIFDANPRMFGIKIRDVEIQDVEKLKDFVKENDIEIGIICVPRTNAQKVCNDLVEGGIKGIWNFAPIDLEVPKDIRVENVHLSESMMTLVYLLNHNDVK
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPH2_MACMU
Sequence: MQPAMMMFSSKYWARRGFSLDSAVPEEHQLLGNLTLNKANSGKNDDKGNKGSSKNETATESGKTAVVFSLKNEVGGLVKALRLFQEKRVHMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI
What are the official names of this protein?
Tryptophan 5-hydroxylase 2, Tryptophan 5-monooxygenase 2.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: KGP2_HUMAN
Sequence: MGNGSVKPKHSKHPDGHSGNLTTDALRNKVTELERELRRKDAEIQEREYHLKELREQLSKQTVAIAELTEELQNKCIQLNKLQDVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDDEKRHAKRSMSNWKLSKALSLEMIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPPDELSGWDKDF
What is the function of this protein?
Crucial regulator of intestinal secretion and bone growth.  Phosphorylates and activates CFTR on the plasma membrane.  Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum (PubMed:33106379).  Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity.  Phosphorylates GRIA1/GLUR1 at Ser-863 (By similarity).  Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts.  Under fluid shear stress, mediates ERK activation and subsequent induction of FOS, FOSL1/FRA1, FOSL2/FRA2 and FOSB that play a key role in the osteoblast anabolic response to mechanical stimulation (By similarity).
What are the official names of this protein?
cGMP-dependent protein kinase 2, cGK 2, cGK2, cGMP-dependent protein kinase II, cGKII.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor.
Protein: MBTP2_PONAB
Sequence: MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLESNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR
What is the function of this protein?
Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2.  Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached.  Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription.  Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B).  Involved in intramembrane proteolysis during bone formation.
What are the official names of this protein?
Membrane-bound transcription factor site-2 protease, Endopeptidase S2P.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50A family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cytoplasm.
Protein: YIDC_ECOBW
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2395_SYMTH
Sequence: MDLHMFVPDFQAMREELTRLGFEELRTAEEVQEKLPTAKGVTLLAINSMCGCAGGIARPAAALALRQVKPDHLMTVFAGQDKEATAAARALFPQYPPSSPSFAVLKDGQAVAMIPRSQIEGSDPQTVAQRIVEAVQAARG
What are the official names of this protein?
UPF0403 protein STH2395.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: UVRB_PSET1
Sequence: MSDHFQLKSHFKPAGDQPTAIAQLCEGLEAGLAHQTLLGATGTGKTFTMANIINDLNRPTIIMAHNKTLAAQLYGEMKEFFPKNAVEYFVSYYDYYQPEAYVVSSDTFIEKDASINEHIEQMRLSATKALLERRDTIIVASVSAIYGLGDPKSYMKMMLLLKVGEKVDQRDMLRRLAEIQYTRNDVDFSRGTYRVRGEVVDIFPAESSTFAIRVEMFDDEIERLSIFDPLTGAIEKHIVRTTIYPKTHYVTPREKILGAIEKIQEELKDRRAQLLSANKLVEEQRVTQRTQYDIEMMRELGYCSGIENYSRYLSGRTPGDPPPTLLDYLPDDALMIIDESHVTVSQIGAMYKGDRSRKENLVEYGFRMPSAMDNRPLRFEEFEAISPQTIYVSATPGDFELDRCVGAIAEQVIRPTGLLDPLIEVRPVGDQVDDLLSEIYKSVEKGERVLVTTLTKRMSEDLTDYLSEHNVKVRYLHSDIDTVERVEIIRDLRAGVFDVLVGINLLREGLDMPEVALVAILDADKEGFLRSARSIIQTVGRAARHLEGRAILYGDRITKSMAKAMDETARRREIQHAYNIEHGIEPHSLAKKILDSMDVGEEAGPKDNLRLIRKESKKVLSAKEITVQIKQLDSKMHAYASDLEFEKAASVRDEIHELQQQLIN
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_RICTY
Sequence: MINQIQKTISVCIIGRPNSGKSTLLNRIIGEKLSIVTPKVQTTRSIITGIITLKDTQIILYDTPGIFEPKGMLEKAMVRCAWSSLYSADLVLSIIDSLKPLDDMAHNILNQFCLLNIVPIFLLNKIDIESKYLNDIKAFLKISHPKSLLFPISALCGKNVDVLLKYIKSKAKVSPWLYADDDITNLPMRFIAAEITREQLFLNLQQELPYKLTVQTEKFEELKDKSIKINQVIVISRESYKAIILGKNGTKIKDIGVKSRIQMEQLFCVPVHLFLFVKVHALWENKQEFYQYMKI
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: SDHL_HUMAN
Sequence: MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHFVCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELAKALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPIFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRALKEQLGMTNRLPK
What are the official names of this protein?
L-serine dehydratase/L-threonine deaminase, SDH, L-serine deaminase, L-threonine dehydratase, TDH.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_CUPMC
Sequence: MALLQISEPGMSPAPHQRRLAVGIDLGTTNSLVAAVRNSIPEVLPDEHGRALLPSVVRYLPNGNAHIGYKAQDEAVRDPKNTIISVKRFMGRGVRDVANIEHSLYDFVDAPGMVQLKTAAGIKSPVEVSAEILATLRQRAEDSLGDELVGAVITVPAYFDDAQRQATKDAAQLAGLEVLRLLNEPTAAAIAYGLDNAAEGIYAVYDLGGGTFDISVLKLTKGVFEVMSTGGDSALGGDDFDQRLLCWIVEQVGLQPLSAEDSRLLMVRARAAKEALSSSDSTVIDAVLTSGEIVHLTLDADTFIQITANLVQKTLTPVRKALRDAGVGPEDVKGVVLVGGATRMPAIRKAVGDYFGQQPLTNLDPDRVVALGAAMQANLLAGNHAPGEDWLLLDVIPLSLGVETMGGLVEKIVPRNSTIPVARAQEFTTFKDGQTAMAIHVLQGERELASDCRSLARFELRGIPPMVAGAARIRVTYQVDADGLLSVSARETGSGVEASVSVKPSYGLADDDIARMLQESFQEAEHDMKNRALAEERVEAARLVEATTRALETDGNLLSADERAAVDELMANVSEIAKGEDHRAIKAAVERLSQGTDEFAARRMDRSIKSALAGKKVQEIG
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ACP_YERPB
Sequence: MSTIEERVKKIIVEQLGVKEDEVKNSASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDFINANQQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4LK_SINFN
Sequence: MKGRECARNEASRSWFGACSFASLPDQAVPACSLGSGEIPMAHGTKQKLMKASDIPAFVNEVIEAGCDICAVGHEKYVIGDTDLSRGAYGKMRQRLGRIEEAYGDRDFLKLEIVAYLRSIGRYVDVGADGSE
What are the official names of this protein?
Uncharacterized protein y4lK.
Protein: TRPA_BUCDN
Sequence: MNRYENIFDRLSQRKEGCFVPFVVLGDPSLDTSLKIINILIQNGADALELGIPFSDPLADGKTIQKANLRALSQKNNIFQYFKEIKNLRKKHTQIPIGLLIYANLVYNQGLDNFYLKCRKSGVDSVLIADVPIEESEIFYTTANKYKISSIFICPPNADDDLLYRISLYAKGYIYVLSRPGVTGIENQNFFVSGDFIKKIKKYNSVPLLQGFGISNSIQVKQAISSGLSGVICGSAIINIIEKYLYEEDIMMTKIQEFVKHLKKSTKLIA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: Y085_METJA
Sequence: MLKKLIGLLTILIIAVGFCGCMEQNIEKQTPTASEAPNTIKVVDLYGREVEVPKEVNRIVCCGPGCLRLIVYLNATDKVVGVEDTEKKWTPWTRPYRIAHPELANLPTIGQGGPCPKPNPEAIIQVKPDVIFVTYMPKDEVDALQQKTGIPVVVLSYGQLATFNNEDLFKSLELAGKILGKEERAKEVIEFIKNCQNDLNERTKDIPDDKKPSVYVGGIGYKGLHGIDSTECKYPPFVAVNAKNVADELGKEGHVFVTKEQILKWNPDIIFIDEGGLKLVVEDYKRNKEFYNSLKAFKNGDVYGLLPYNFYTTNIGTALADAYYIGKVVYPDRFKDIDPEQKADEIFTFLVGKPVYKEMKEKLGGFKKLEFSS
What are the official names of this protein?
Uncharacterized lipoprotein MJ0085.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DGTL1_MYCS2
Sequence: MNATQYDHYDDFDRERLVPEPAKSAALPGTDTEHRTDFARDRARVLHCAALRRLADKTQVVGPRHGDNPRTRLTHSLEVAQIGRGMAIGLGCDPDLVDLAGLAHDIGHPPYGHNGERALNEIAKAFGGFEGNAQNFRILTRLEPKVLDADGRSAGLNLTRASLDAVTKYPWRRTEERRKFGFYVGFPDDDGPAADWVRDGAPVDRPCLEAQVMDWADDVAYSVHDVEDGVISGRIDLRVLADADAAESLAQLGAAAFPSLAHDDLLAAAQRLSEMPVVAAVGKYDGTLAASVALKRLTSELVGRFANAAITETRAVAGDRPLKRFDSDLVVPDLVRAEVAVLKMLALQFIMSDHQHLQVQADQRTRIHEVALALWAQAPGSLDPQFAPEFAAAGDDGARLRVVIDQIASYTETRLERVHEARSPRPLE
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: RUVA_LACDB
Sequence: MYEYFEGTITVVNPAYVVIEVAGIGYRILTPTPYAYKEGDKARIYVEQVVRENGMTLYGFKSQQDKVLFNKLNEVSGIGPKSALAIMAAEDNGALASAIESGEVSYLTRFPGIGKKTASQIVLDLRGKMGNYVAENLFTEDEPVESVFPALEDALLALGALGYSQKEVDRIKPKLKKLPEMSADEYIKQGLGFLLKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL30_CANAL
Sequence: MAPKSNKNQENINSKLALTIKSGKYTLGYKSVVKSLRTGKAKLVIIAANTPVLRKSELEYYAMLSKTPVYYFQGGNNELGTVCGKLFRVGTLSILDAGDSDILSSI
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: RK23_OENEH
Sequence: MDGIKYAVFTDKGVRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVQAMNSHRLPGKGRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y659_BART1
Sequence: MTQCNGFLGGQLLIAMPGMNDKRFMRSVIYICAHSDAGAMGIILNQLHHIDFPELLLHLGVIDSGQKKCLSEPIKQFPVRYGGPVDPSRGFVLHSDDYACEETVFIADKVCFTATIDILKAISCEQGPQHALVALGYAGWKAGQLEAEISTNGWLISSTSPSFLFESDLSCKYDKSLTRMGIDPTYLASEMGHA
What are the official names of this protein?
UPF0301 protein BT_0659.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: GLND_PSEF5
Sequence: MPQVDPELFDRGQFQAELALKASPIAAFKKAIRQAREVLDTRFRSGREIRRLIEDRAWFIDNILQKAWDQFSWSEDADIALVAVGGYGRGELHPYSDIDLLILLDSADHEIFRDSIERFLTLLWDIGLEVGQSVRSVDECAEQARADLTVITNLMESRTIAGPEHLRQRMLQVTSTEHMWPSKDFFLAKRAEQKARHHKYNDTEYNLEPNVKGSPGGLRDIQTILWVARRQYGTLNLRALAGEGFLVESENALLASSQEFLWKVRYALHMLAGRAEDRLLLDHQRSIATLLGFEGEDAKQSIESFMQQYYRVVMSIAQLSDLIIQHFEEVILAPEDEAPPQPINARFQLHDGYIEAINDNVFKRTPFAMLEIFVLMAQHPEIKGVRADTIRLLREHRHLIDDDFRHDIRNTSLFIELFKCEIGIHRNLRRMNRYGILGRYLPEFGFIVGQMQHDLFHIYTVDAHTLNLIKHLRKMQYTPISEKFPLASKLMGKLPKPELIYLAGLYHDIGKGRHGDHSEIGAVDAEAFCVRHQLPQWDTRLIVWLVQNHLVMSTTAQRKDLSDPQVIHDFAQIVVDQTRLDYLYVLTVADIYATNPTLWNSWRASLLRQLYTETKRALRRGLENPVDREEQIRQTQSAALDILVRNGTDPDEVEQLWSQLGDDYFLRHTAGDVAWHSDAILQQPADGGPLVLIKEITQREFEGGTQIFIYAPDQHDFFAVTVAAMDQLNLNIHDARIITSSSQFTLDTYIVLDNDGESIGNNPQRVEQIRKGLTDALRNPDDYPTIIQRRVPRQLKHFAFAPEVTIHNDAQRPVTVLELSAPDRPGLLARIGKIFLEFDLSLQNAKIATLGERVEDVFFITDAHNQPLSDPQLCSRLQDAIVEQLSVSHEPTIEMTRLSI
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: RAD25_NOSCE
Sequence: MNNVMLPKKAQKHQFPVEEIILKDDHENFSLWINYDALIILETFKQNSKQASDFLIAIAEPVSRPKYIHEYQITAYSLYAAVSVGLSTDDILSTLSYFSKNIMPRSVKNFIVECTLSYGKIKLVIQFNKYFIEAANNDILKKLIDDKIIRSNLFVTDNSVEVINVELVKKRCIEIDYPLIEEYDFKNDTVLESFFIDLKPSTMIRSYQETCLNKMFCNGRARSGIIVLPCGSGKTLVGITALTTIKKSCLILCTSAVSVEQWRQQTMLFTNISGDNICRFTSEYKEWYKDKCGIIITTYTMLAYNGKRSPEAQKIMDLIQSTEWGLLLLDEVHVVPAMMFRKVISLVTHHCKLGLTATLVREDDKIEDLNFLIGPKLYEADWQDLSAKGHIAKVECFEVWCGMTGEFYKEYLIQTSRKKRLLSIMNPTKFQACEYLISRHEAKGDKIIVFSDSVAALKSYALKLGKPFIYGPTGQTERMRILKQFQTNPLINTIFLSKVGDTSIDLPEATCLIQISSHFGSRRQEAQRLGRILRAKRRNDPDFKVFFYSLVSKDTDEMFYSSKRQQFLVDQGYSFNIITEIPEIYKNENRVYKSKSQQKELLVSVLLSSDKELESDTEADNEEIGVYSGILKGSTGVDGMAYMETNERNDLGKNKRRRK
What is the function of this protein?
ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  The ATPase activity of XPB/SSL2, but not its helicase activity, is required for DNA opening.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  The ATP-dependent helicase activity of XPB/SSL2 is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, DNA repair helicase RAD25, RNA polymerase II transcription factor B subunit SSL2, TFB subunit SSL2, Suppressor of stem-loop mutation 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD25/XPB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LAP1_PODAN
Sequence: MKASLLALLLPAVSARNVNLAGDTQRPMTHEEAAAATYHIEISPGNTRWVTEDEKWALRRKGINFFDITDHPDLGATINTLVGPPKKKAVFPKKPTYQDAVKPLFTNLSKSHLEENLEKFTSFHTRYYKSDWGRQSSEWLLGKVQETIKEAGAEKYVTAKHFKHPWGQNSIIATIPGKTNQTVVIGAHQDSINLFLPSILAAPGADDDGSGTVTILEALRVILQSKDIVKGKHPNTLEFHWYSAEEGGLLGSQAIFSAYEKERRDVKAMLQQDMTGFITRTIQAGLPESVGVIVDFVDPKLTEFIKKIITEYCDIPFVETKCGYACSDHASASKAGYPSAFVIESAFEYSDNHIHTTDDLIKYLSFDHMIQHAKLTLAFAYELAFADFPALEKGK
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RR2_CHLSC
Sequence: MTRRYWNINLEEMMEAGVHFGHGTRKWNPRMAPYISAKRKGIHITNLTRTARFLSEACDLVFDAASSGKHFLIVGTKNKAADSVASAAIRARCHYVNKKWLGGMSTNWSTTETRLQKFRDLRAEQKMGRLNRLPKRDAAMLKRQLSRLQTYLGGIKYMTGLPDIVIIVDQQEEYTALRECVTLGIPTICLIDTNCDPDLADISIPANDDAIASIRLILNKLVSAICEGRSGYIRNR
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NAR1_SCHJY
Sequence: MVKLSAEDLNDYLNPGVACVKPVKVQKKQDNQQNIKVNGESYYEVTKDTGEVEELGIASISLNDCLACSGCITSAESVLINLQSYHEVLKFVNAKEADDFFILQMSPQARASLAAYYNLSVQEVQLWIQSVFTNELKFNVVVDTGFSREISLRQAAIEFCQSWVAANAAKTVYNSKSGEVAPKPLPVLSSSCPGWICYVEKTHSSLIPHISTVRSPQQVAGRLLKDWFSYQLGISRKKIWVLSLMPCFDKKLEASRNDFVNEQVRDVDCVITPKELVELLKTKNISPQSMDLDSLSISEQTPCLPSWYEPVQFEQQNGSSSGGYLHYIMTFAAKALFDINDLTNRINVSQKNADMIEYELTSPDTGETLLRMATCYGFRNIQNLVRNVGRKSAPRRGRVLLKRMKNMSTSPSTGTGKQKLDYVEVMACPGGCINGGGQLPPPESSADFSGISREWMRQVEAHYFQPGVRQVDNAAVDAAVEHWLPSYSLQQSILHTKYHAVQNDTENPVALANTW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1 homolog, Nuclear architecture-related protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NARF family.