PharMolix/UniProtQA huggingface dataset:
Protein: NIFH_SOLM1
Sequence: MRKIAIYGKGGIGKSTTTQNTVAGLAEMGKKVMVVGCDPKADSTRLLLHGLAQKTVLDTLREEGEDVELDDILKEGYGGTMCTESGGPEPGVGCAGRGIITSINLLEQLGAYEEDKKLDYVFYDVLGDVVCGGFAMPIRDGKAEEIYIVCSGEMMAMYAANNICKGIVKYADTGGVRLGGIICNSRKVDFEKEMIEELCRQIGTQMIHFMPRENQVQRAEINRKTVIDYSPEHAQADEYRALAKKIDENKMLVIPKPLEIAQLEKLLVDFGIAN
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: SPIKE_ADECT
Sequence: MKRTRRALPANYDPVYPYDAPGSSTQPPFFNNKQGLTESPPGTLAVNVSPPLTFSTLGAIKLSTGPGLTLNEGKLQASLGPGLITNTEGQITVENVNKVLSFTSPLHKNENTVSLALGDGLEDENGTLKVTFPTPPPPLQFSPPLTKTGGTVSLPLQDSMQVTNGKLGVKPTTYAPPLKKTDQQVSLQVGSGLTVINEQLQAVQPPATTYNEPLSKTDNSVSLQVGAGLAVQSGALVATPPPPLTFTSPLEKNENTVSLQVGAGLSVQNNALVATPPPPLTFAYPLVKNDNHVALSAGSGLRISGGSLTVATGPGLSHQNGTIGAVVGAGLKFENNAILAKLGNGLTIRDGAIEATQPPAAPITLWTGPGPSINGFINDTPVIRCFICLTRDSNLVTVNASFVGEGGYRIVSPTQSQFSLIMEFDQFGQLMSTGNINSTTTWGEKPWGNNTVQPRPSHTWKLCMPNREVYSTPAATISRCGLDSIAVDGAPSRSIDCMLIINKPKGVATYTLTFRFLNFNRLSGGTLFKTDVLTFTYVGENQ
What is the function of this protein?
Forms spikes that protrude from each vertex of the icosahedral capsid.  Interacts with host receptor to provide virion initial attachment to target cell.  Fiber proteins are shed during virus entry, when virus is still at the cell surface (By similarity).
What are the official names of this protein?
Fiber protein, SPIKE, Protein IV.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae fiber family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Anchored to the pentons, protrudes from the virion surface.
Protein: NUSB_BURCJ
Sequence: MKKSARRQSRELATQGLYQWLLSNAPSGEIDAQLRGALGYDKADKELLEAILHGVIREHATLVEALAPSLDRPIDQLSPVERAVLLIATFELTHHVETPYRVIINEAVELAKTFGGSDGYKYVNGVLDKLAAKLRPAETQARRNG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RS7_BACCN
Sequence: MPRKGPVAKRDVLPDPMYNSKLVTRLINKMMVDGKKGKSQTILYNAFDIVRERTGKEPMEVFEQALKNIMPVLEVRARRVGGANYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNTGASVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GAG13_HUMAN
Sequence: MSWRGRSTYYWPRPRRYVEPPEMIGPMRPEQFSDEVEPATPEEGEPATQRQDPAAAQEGEDEGASAGQGPKPEADSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGEKQSQC
What are the official names of this protein?
G antigen 13, GAGE-13, G antigen 12A, GAGE-12A.
What is the protein family that this protein belongs to?
Belongs to the GAGE family.
Protein: RS5_CARHZ
Sequence: MARIDASQLELSEKVIAINRTAKVVKGGRRFSFSALVVVGDQKGHVGVGLGKAPEVPDAIRKGIEDAKKNLIKVPIVNTTIPHEIIGEAGAGKVLLKPAAPGTGVIAGSAVRAILEMAGVRDILTKSLGSNNPHNMAHATIEALKSLKTVEMVAKLRGKTPAEILKG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HOXX_BRADU
Sequence: MRILLLSHSFNSLTQRLHVELRERGHEVSVELDIHADVTRESVALHRPDLVIAPFLKRAIPDDVWRSVRCLVVHPGPPGDRGPAALDWAVLEGVAEWGVTVLQADGEFDAGPIWSFRSFPMRCAAKSSIYRNELTSCAVAAVLEAVAAIEAGQAAPQPMQAGDPRIRVRGPCRQADRTIDWQHDSTMTVLRKINSADGMPGLVDSLFFQEVRLFDAHEAHDISGVPGTVIAQCEGALARATVDGAVWIGHVKRLAPKSLKLPAAKVFAAEAAYLPHRPGCGYAPIRYREHGEVGELAFSFYNGAMATGDCEALLGAYRAALERPTRVLLLTGGPDYWSNGIHLAEIEAAESAADESWRNINAIDDLARAIIETTDRLVVSVIRGNAGAGGVFLSLAADEVWASDQIILNPHYKDMGNLYGSEYWTYLLPRRAGAANATRITQCRLPMGVAEARRLAIVDRVLSGEALADASLVQSGAAMASDAGFAARLAAKQQRRAADEAEKPLQSYRDEELRRMKLNFYGFDPSYHVARYNFIHKVPKSRTPLTIAGHRIRRAPGRPVGMAVSS
What is the function of this protein?
Involved in the post-translational processing of the hydrogenase large subunit.
What are the official names of this protein?
Hydrogenase maturation factor HoxX.
Protein: DF287_ARATH
Sequence: MNNLRVIMSVLLAVLVFTATVSESAEEMGKGEVTISLRCKTKTECLKNIACEACVDCRCDKGICKCHGFTAETNNPTV
What are the official names of this protein?
Defensin-like protein 287.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASNA_MANSM
Sequence: MKKSFILQQQEISFTKNTFTEKLAEHLGLVEVQGPILSQVGNGIQDNLSGTEKAVQVNVKMITDAAFEVVHSLAKWKRHTLARFGFAEGEGLFVHMKALRPDEDSLDQTHSVYVDQWDWEKVIPEGRRNLDYLKETVREIYAAILETEAAVDKKYGLKSFLPKEITFIHSEDLVKDYPGMTDKERENELCKKYGAVFLIGIGGVLPDGKPHDGRAPDYDDWTTTSEGEYKGLNGDILVWNPILNRAFEVSSMGIRVDETALRKQLSITGDEDRLKFDWHQDLINGRMPLSIGGGIGQSRLAMLLLQKRHIGEVQSSVWPKAVMEQYENIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMN6_SHEPW
Sequence: MPFSFKQFHIDDRRCGMPVSTDGVLLGAWAPLSNSKNILDIGAGSGLLSLMAAQRSKANITAIELDENAALDCQSNFNLSPWSKRLTLLTRSIQQFCTTAKKHSFDHIICNPPYFDNGPQSNSALRATARHTDSLSFDELLTAISSLLSPAGQASLILPITGANQLLQQLEQHQLTCQHAVLVASVEGKKPNRQLLLITPCRSNFANQATTHPVSNLVIRNTDGHYSDDFILLSKSFYLKL
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CAPIB
Sequence: MTNIRKTHPLMKIVNNAFIDLPTPPNISSWWNFGSLLGTCLILQILTGLFLAMHYTSDTMTAFSSVAHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAMVHLLFLHETGSNNPTGIPSDTDKIPFHPYYTIKDILGAMLLILVLMLLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILVLVPFLHTSKQRSMMFRPISQCMFWVLVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLTILVMMPAASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS8_CLOBJ
Sequence: MVMSDPIADLLTRIRNANVVRHEVVEVPSSNIKKAIANIMLTEGYIRDLEEYRDGSVDMLRITMKYGQNKERIITGLKRISKPGLRVYCRKDETPKVLNGLGVAVVSTSKGIVTDREARKLGVGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MC4R_PIG
Sequence: MNSTHHHGMHTSLHFWNRSTYGLHSNASEPLGKGYSEGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAVCTVSGVLFIIYSDSSAVIICLITVFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
What is the function of this protein?
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH.  Plays a central role in energy homeostasis and somatic growth.  This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
What are the official names of this protein?
Melanocortin receptor 4, MC4-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS5_UREPA
Sequence: MENNVKKETIVDSEKVEKQQLVTAPVVNKKENTEPKAKTFKRETTTSNFEERVVKIKRISKTTKGGRMMRFSALVVIGDKNGTVGFGMGKSIEVPDAIKKAIKNANNNLIKVKQTKKGSIYHDVNGRHGAAKVMLLPAPEGTGIIAGGPVRAVVELAGFTDIYTKSRGANAPMNVIRATINGLLQQLTPKEIARLRDKSLREI
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: LPXD_RUTMC
Sequence: MYTLGEIAKTINAKLVGDANIEITGIATSLSANQTQLTYINGNKYKQMLINSKAGVVILNNNLLKNCPTNALVVDNVYLAFAKATHLFKKQTVHCQGTHSSAKINYAKIAPNCIIGKNVVIGNHCTIAPNVVIEDDVIIGNYTLIQPNVSILQGCSIGNNVVISPGVVIGSEGFGNAQDQQKHWYSIAHLGYVIIGSNVSIGANTTIDRGTIEDTQIHNGVQIDNLVHIAHNVIIGQDSAIAATVTIGGSCTIGKRCMIGGGATIASHISLVDDIIVTGASTVDKNLSEQGHYTGFTSINKHQKWKKIQVWLLNLDKIAHYLNIKLKELKGK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: TRPA_SALPC
Sequence: MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDSGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAELRSFVSAMKAASRA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: PSBB_LEPVR
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWNITGGTITNPGLWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQPVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSAGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRNKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGSRTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKRQAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CLPB_PSESM
Sequence: MRIDRLTSKLQLALSDSQSLAVGLDHPAIEPAHLMQALLEQQGGSIKPLLLQVGFDINSLRKELSAELDRLPKIQNPTGDVNMSQDLARLLNQADRLAQQKGDQFISSELVLLAAMDENSKLGKLLLGQGVSKKALENAINNLRGEGAVNDPNIEESRQALDKYTVDLTKRAEEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIAEGLAQRIINGEVPDGLRGKRLLSLDMGALIAGAKYRGEFEERLKSLLNELSKQEGQIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLNEYRQYIEKDAALERRFQKVLVDEPSEEDTIAILRGLKERYEVHHKVAITDGAIIAAAKLSHRYITDRQLPDKAIDLIDEAASRIRMEIDSKPEVLDRLERRLIQLKVEAQALKKEKDEAAIKRLEKLQEEIVRLEKEYADLEEIWTSEKAEVTGSAQIQQKIEQSRQELEAARRRGDLNRMAELQYGIIPDLERSLQMVDQHGKPENQLLRSKVTEEEIAEVVSKWTGIPVSKMLEGEREKLLRMETLLHNRVIGQEEAVVAVSNAVRRSRAGLSDPNRPSGSFMFLGPTGVGKTELCKALAEFLFDTEEAMVRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHSDVFNILLQVLEDGRLTDSHGRTVDFRNTVIVMTSNLGSAQIQELVGDREAQRAAVMDAVSTHFRPEFVNRIDEVVIFEPLARDQIAGITDIQLGRLRKRLAERELTMVLSPEALDKLIAVGYDPVYGARPLKRAIQRWIENPLAQLILSGGFEPGSSITGKVVDDEIVFG
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_CHAMQ
Sequence: EGDVIATGINGFGRIG
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_CLOD6
Sequence: MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGDSLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGRLIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSETARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQDMLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_CLOBM
Sequence: MDFTNLKNTDPELLDMIKKEEERQEYNIELIASENFTSLSVMEAMGSLLTNKYAEGYPHKRYYGGCEFVDEVEDLARERLKKLFAAEHANVQPHSGSQANMAVYMSVLQTGDTILGMDLSHGGHLTHGSPVNFSGKLYNFISYGVDKETETIDYEQLKKIALENRPKMIVSGASAYPRIIDFQKIREICDEIDAYMMVDMAHIAGLVATGLHPSPVPYADFVTTTTHKTLRGPRGGAILCKEKYAKAVDKAIFPGIQGGPLMHTIAAKAVCFGEALREDYKEYMQQVVKNTKVLGEELKNYGFRLISGGTDNHLLLIDLTNKNITGKDAEKLLDSVGITVNKNTIPFETLSPFITSGIRIGTPAVTTRGFKEEEMKKIAYFMNYSIEHREENLSQIKEQIKEICKKYPLHQNA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_THEVB
Sequence: MVQRWWEITVTCQAEAEELVYWRLQSFGCQGTATQLQQGRVLIQGYVPQQRVSLLDIAALGVWIEQDVVAQGYLSPKLHWQLVNEQDWAHSWQAYWHPIPVGDRLLICPAWEMPPLDNTRLVIKLDPGMAFGTGTHETTQLCLEALEMQLDQTFEPLPPTVIADIGCGSGILAIASLLLGAQKAYAVDTSDLAVTATQRNAELNGIRADQLIVHQGSWEQVLELVDGVVCNILAPVIIEILPHLPAIVKPKGWGIFSGILLDQADRVAEQLKRQGWSLGSVWRRNEWCCLNARFERLPD
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_COREF
Sequence: MRITARAWGKINLHLGVGPAREDGYHELVTVFQTIDLAETITLTTLEDELVEEGSVVRQLTVTGPRGVPTTPDNLAWRAVDALVGRRREHDRTPLPAVELHIDKGIPVAGGMAGGSADAAAALRAVDAWIGPFGEETLLEVAAELGSDVPFCLLGGTKLGTGRGEQLVDMLSRGTYHWALVVSPKGLSTPEVFAKFDEMSLPSSMDVTPMSQALLDGSAGALAEVLENDLAPAALSLRPDLRKTQLAGLRAGALATMVSGSGPTIALLCDDAQSARDVADALMDEGVGLSVHPATSPVPGPAKNRGAHIVSIESE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MC4R_RAT
Sequence: MNSTHHHGMYTSLHLWNRSSHGLHGNASESLGKGHSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLITMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELPGRY
What is the function of this protein?
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH.  Plays a central role in energy homeostasis and somatic growth.  This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
What are the official names of this protein?
Melanocortin receptor 4, MC4-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IRA1A_ONCMY
Sequence: MKVGFALVLLWSLPITNVLAELPQPQNLTLLTLNTQYVLTWDWDQTTTGNSVSFTVEYMAKYKMKMKKKNWSRVCERTTRTRCDLTGSDLHYLGMYVLRVRASADGVNSDWVNKDFCPDIDASLGPPSRVELAPVGNLLDVTISDPLTSTQHSMKEHVLFLYYRILYWSRSDDPQGLKPKVLDSSNNLVTLPELEAWTWYCVMIQSRYDYYNKTSSYTEPQCMQTEGDTPYGQIFLYFLVSMMVCFLLVLLSSYAFFRFYRGLKNTFYPSIQLPAHIQEYLCDSSPGSDMPRLITADSEAELCCDKLTICPEVVLLEIHVPPPLTAPPSELEQDSGRRIRQDSGDSGIYSTEGGSAQQGRSGGEPIRRDQEVDSWQTLEQVKMEEMGRELADERDLDEGVVDICV
What is the function of this protein?
Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa).  Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response.  Mechanistically, type I interferon-binding brings the IFNAR1 and IFNAR2 subunits into close proximity with one another, driving their associated Janus kinases (JAKs) (TYK2 bound to IFNAR1 and JAK1 bound to IFNAR2) to cross-phosphorylate one another.  The activated kinases phosphorylate specific tyrosine residues on the intracellular domains of IFNAR1 and IFNAR2, forming docking sites for the STAT transcription factors.  STAT proteins are then phosphorylated by the JAKs, promoting their translocation into the nucleus to regulate expression of interferon-regulated genes.
What are the official names of this protein?
Interferon alpha/beta receptor 1a, Membrane-associated type I interferon receptor, mIFNAR1, Type I interferon receptor 1a.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NTA_CORVA
Sequence: ACSRAGENCYKSGRCCDGLYCKAYVVTCYKP
What is the function of this protein?
Insecticidal toxin that induces reversible paralysis in crickets but not in cockroaches and mice.  Molecular target unknown.
What are the official names of this protein?
U1-theraphotoxin-Cv1a, U1-TRTX-Cv1a, Covalitoxin-2, Covalitoxin-II, CvTx-II.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_MARN8
Sequence: MANSPQAKKRARQNEKNRKHNASLRSMARTYMKKVDAKIKAGNHDEAQAALKEAQPIMDSMVNKGIFAKNKIARHKSRLNAKIKALKSA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: TRI54_RAT
Sequence: MNFTVGFKPLLGDAHNMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEDEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQKFETLCAVLEERKGELLQALARVQEEKLQRVRSLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFSVIVEHVAEMLRTIDFQPGASGDEEDDEVTLDGEEGNTGLEEERLDGPEGLH
What is the function of this protein?
May bind and stabilize microtubules during myotubes formation.
What are the official names of this protein?
Tripartite motif-containing protein 54, RING finger protein 30.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity).
Protein: PLSY_FRAT1
Sequence: MNFLNFSILIFAYLLGSINSAIIVCYIFRLPSPRSVGSGNPGMTNVLRIGGKVPAAITLIFDILKGLVPVVIAKVLTGNEFITACTALYAILGHIFPIFFGFKGGKGVATLIGTLFGFSWILGLIFVITWLCVAIITRYSSLSALVATVIASFSVIFTSDLQVAAPFLIIAIIILVKHKGNIQRLISRQESKIGDKAKAKNDSN
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.