PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_STRZJ
Sequence: MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVISTWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDIIADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKDIDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLPGSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNATLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLLANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDGAVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQDTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGKK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CYSC_STACT
Sequence: MVKSQNITWHDSEVTKNERQEKNGHKSVVLWFTGLSGSGKSTISVALEKALFERGVRSYRLDGDNIRHGLNNNLGFSPEDRKENIRRIGEVSKLLSDAGLITLTAFISPYREDRDHVREILEDGEFVEVYTKASVAACEERDPKQLYKKVRAGEIKNFTGIDAPYEAPEDPEIIVDTEENSVEEAVEQIIQYLEDQKVI
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: HCP_SHEWM
Sequence: MFCIQCEQTIRTPAGNGCSYSQGMCGKLAETSDLQDLLIYILQGVSAYAVKAREFNIIDAEIDTFVPKAFFATLTNVNFDDARLIEYVEQANTYRTRLKDAYEAQCAANGVMVAEMSAPAQLVLATAKPELLAQAPLAAPNRGDVHEDILGLRLLCLYGLKGAAAYMEHARVLDQTDAEVAGSFHEIMAFLGEDSVDVDKLFATSMEIGQLNYKVMAMLDEGETNAFGHPEPTQVNTVAVKGKAILVSGHDMVDLELILKQTEGKGINVFTHGEMLPALAYPEFKKYPHLVGNYGSAWQNQQKEFANFPGAVVMTSNCIIDPNVGNYSDRIFTRSIVGWPGVTHLVGDDFTQVIEKALALDGFIYDEIPHLITIGFARNALMAAAPAVIENVKNGSIKHFFLVGGCDGDKADRSYFTDIATQAPDDSLILTLGCGKYKFNKLEFGDINGIPRLLDIGQCNDSYSAIQLAIALSEAFECEINELPLSLVLSWFEQKAIVVLLTLLSLGVKNIRTGPTPPAFLTENLLNILEEKFGLRNTTTVEADLNTILNVA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEKT3_HUMAN
Sequence: MERVGCTLTTTYAHPRPTPTNFLPAISTMASSYRDRFPHSNLTHSLSLPWRPSTYYKVASNSPSVAPYCTRSQRVSENTMLPFVSNRTTFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMRKSYPNTLRLVGFC
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme.  Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity).  Required for normal sperm mobility (By similarity).
What are the official names of this protein?
Tektin-3.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane; Peripheral membrane protein. Note=In the sperm flagellum, localizes to the periaxonemal region where it associates with the mitochondrial sheath and outer dense fibers (By similarity). Not detected in the central axonemal region of the flagellum (By similarity). Associates with the acrosome membrane in the equatorial segment of the sperm head (By similarity). Also detected just below the plasma membrane in the post-acrosomal region where it might localize to the postacrosomal dense lamina (By similarity). However, other studies report little or no expression in the postacrosomal region (By similarity). Translocates from the postacrosomal region to the equatorial segment after sperm activation (By similarity). Retained in the postacromal region, but not the equatorial segment, following the acrosome reaction (By similarity). Some studies report strong expression in the anterior cap region (By similarity). However, other studies report little or no expression in the acrosomal cap (By similarity).
Protein: Y4418_BACCQ
Sequence: MKVSYHGHSVVKIETNGKVMLIDPFLTGNPKTDLKAEDVKVDAILLSHGHGDHVGDTVELAKKNNAVVVAPFELATFLSWQGVKTHPMHIGGSHEFDFGKVKFTQAFHGSSYIDEENKTITYTGMPAGILFTAEEKTLYHAGDTALFSDMKLIGELNNVDVAFLPIGDNFTMGPEDAVLAAKWVQAKTVVPMHYNTFPVIEQDPYQFVEKLQNCTGKVLEAGESITL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase BCQ_4418.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: LEPA_RHOPA
Sequence: MTTAPIDNIRNFSIVAHIDHGKSTLADRLIQITGGMSDREMAGKEQVLDSMDIERERGITIKAQTVRLKYRAHDGKDYIFNLMDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYHALDAGHEIVPVLNKVDLPAAEPEKIKQQIEDVIGLDASDAVMISAKTGLGVPDVLEAIVTRLPPPKGDRDATLKALLVDSWYDVYLGVVVLVRVVDGVLKKGQRIRMMGTGAAYDVERVGYFTPKMVNVEELGPGEVGFITAAIKEVADTRVGDTITDDKKPVTDMLPGFKPAIPVVFCGLFPVDADDFETLRAAMGKLRLNDASFSFEMETSAALGFGFRCGFLGLLHLEIIQERLSREFDLDLIATAPSVIYKMKLTDGTEMEIHNPVDMPDVVKIAEIEEPWIEATILTPDEYLGSVLKLCQDRRGNQKELTYVGARAMVKYDLPLNEVVFDFYDRLKSVSKGYASFDYHLTDYKPADLVKMQILVNAEPVDALSMLVHRTRAEGRGRAMVEKMKELIPPHMFQIPIQAAIGGKVIARETVRALRKDVTAKCYGGDITRKRKLLEKQKEGKKKMRQFGKVDIPQEAFIAALKVDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TMM80_HUMAN
Sequence: MLPNVGSPPLPFRKCPSGAGRTNRASAVARTSAPETRRGRAPSSGDAKMAEGARARGPRGCRDRDGPAGGAGKMAAPRRGRGSSTVLSSVPLQMLFYLSGTYYALYFLATLLMITYKSQVFSYPHRYLVLDLALLFLMGILEAVRLYLGTRGNLTEAERPLAASLALTAGTALLSAHFLLWQALVLWADWALSATLLALHGLEAVLQVVAIAAFTR
What are the official names of this protein?
Transmembrane protein 80.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: VPB34_MYCTU
Sequence: MELAARMGETLTQAVVVAVREQLARRTGRTRSISLREELAAIGRRCAALPVLDTRAADTILGYDERGLPA
What is the function of this protein?
Antitoxin component of a possible type II toxin-antitoxin (TA) system.  The cognate toxin is VapC34.
What are the official names of this protein?
Putative antitoxin VapB34.
Protein: RRG9_YEAS8
Sequence: MNILRIACRSFHCLRCGPLLNENRGWSSKKIIKLVNKSSLSNKEFTEKVRDGTKDIPEWKKQKMAVRKKLQGQRWNPPKKISQEQMEALRLLKFNFPELTASDLADRFKISPEAVRRILKSNWKRTDEENNNTYERWKRRGERIKEMYQRKEDADFVSNQIVTSRKIILGSNSNSPELIARNVRTFKPFKPNNSTPEKKNTNKLYILKHLGSKQ
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
Protein: PAND_BORA1
Sequence: MQRIMLRAKLHRVTVTEADLHYEGSCGIDEDLLDAAGMREFERIELYNVTNGERFDTYIIKAARGSGAISLNGAAARRAQVGDLMIICTYGPMSEEESATHKPKVVLVDDANRVKEIRKFPA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX3G_MESGB
Sequence: MKVFSAVLIILFVCSMIIGISEGKEIPVKCKHSGQCLQPCKDAGMRFGKCMNGKCNCTPK
What is the function of this protein?
Potassium channel inhibitor.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 3.16, MegKTx4, Tx4.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NS1_I79A2
Sequence: MDSNTITSFQVDCYLWHIRKLLSMRDMCDAPFDDRLRRDQKALKGRGSTLGLDLRVATMEGKKIVEDILKSETDENLKIAIASSPDPRYITDMSIEEISREWYMLMPRQKITGGLMVKMDQAIMDKRIILKANFSVLFDQLETLVSLRAFTEDGAIVAEISPIPSMPGHSTEDVKNAIGILIGGLEWNDNSIRASENIQRFAWGIRDEDGGPPLPPKQKRYMARRVESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: RLMN_LEPBA
Sequence: MKEEIPVLKGKTKKELEEICVSLGLEKYRAAQIYTGIYKSRYTTIDQFTTLSKEVREKLKEHTQYPEIEIGRDLVSKEDGTRKFTFYVGENKEIEAVWIPSGDGGRKTICISSQIGCTLNCKFCATGLLEYKGNLQTWQILDQVLQVERLVGDRATNIVFMGMGEPMHNYFSVMKAAHILRDKDAFGLGALRITISTAGVTTGINRFIENKEPFNFAISLNHPNPNARSSVMDVNDKHPLEKLIDSAKRFTKELDRAITFEYVMIPDVNMGRDNAERLAKIARSVNKCKINVIPLNTDFTGWRRPTDDEVKDFVMHLKAKTTAPILNRRSPGRDINGACGMLALKGIRSETTK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_SPICI
Sequence: MDKVKFKKGDLVKVIAGKHKGTEGPIIRVLREKSRVVIEGITNIKHVKPSQDNTEAGI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SLAI2_BOVIN
Sequence: MEDVNSDVNADQEVRKLQELVKMLEKQNEQLRSRSGAVQGAGSFGPGSPVRAGASTPSSGTASPRGFPLGLSAKSGSGAGSGPRRTSSEELRDATSLLAAGEGGLLDEVEPLRPEELERLSGWEEEEESWLYSSPKKKLTPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQTMSALKRQNLYNNPFNSVSYTSPYSPNASSPYSSGFNSPSSTPVRPPIVKQLILPGNSGNLKSSSDRNPPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAATASRRSSGSSCNSTRRGTFSDQELDAQSLDDEDDNMHHAVYPAVNRFSPSPRNSPRPSPKQSPRNSPRSRSPARGIEYSRVSPQPMISRLQQPRLSLQGHPTDLQTTNVKNEEKLRRSLPNLSRTSNTQVDSVKSSRSDSNFQVPNGGIPRMQPQASAIPSPGKFRSPAAPSPLALRQPVKAFSNHGSGSPGSQETTQLMQTTSSPGPPMVQNTVPANPPSNINSTTLTRPAGTTVMRSGLPRPSAPSAGGIPVPRSKLAQPVRRSLPAPKTYGSMKDDSWKDGCY
What is the function of this protein?
Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization.  Promotes cytoplasmic microtubule nucleation and elongation.  Required for normal structure of the microtubule cytoskeleton during interphase (By similarity).
What are the official names of this protein?
SLAIN motif-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the SLAIN motif-containing family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules (By similarity).
Protein: NFT1_YEASX
Sequence: MIKNGTCPYWERDDLSECARREYIEFKFPLFILLTGMIYAFCKVFRAFYLRGKNHTNEAPEFEEQGNGNHEYARFSVLRLKSAWESRSFCNVNNRSTFDKFKKFIEGAFIVLQLTIHLYILSSMPMDNKKFFHQGFLVQMFLWILLLVVITLRLISASQSFRWVLACKRDLWAVSFYSYASLFTLSILPLRSVFIGKIKDKIMVKYIISETFIDLALLLLLSTSSIEGTRYSFLVENENKKLPPAPTVFGLLTFSRIDRLIWKAYKHCLGNADIWDLDINNKSIAILANFEMSSKKGRLLPNIICYFKAVFISQLFLAFVSSFLNFVPSLLMPRILSYVNDPKSKSWNLVSLYVSSMLVSKIIATTCRGQGLFLGEKGTMQLRTVLISNIYSKTLRRTILKDSTTSLQKNASTSFEENPDSSEAEPRKKSSRKDNSVNNVMSIDAFKVSEAMNTFYLACEAVFMTVTALMILYSLLGWSAFAGTFALLAMIPLNFWCATFYGNYQADQLILTDKRTSGISEALNSIRVIKLLAWENLFYQKIINVRDGEIRLLKKKATIFFLNHLIWFFGPTLVSAITFSVFIKFQNQTLTPTIAFTALSLFAILRTPMDQIASTVSLLIQSFISLERIQDYLNESETRKYEILEQSNTKFGFEDASMEWEAAETSFKLKNISIDFKLNSLNAIIGPTGSGKSSLLLGLLGELNLLSGKIYVPTVESRDDLEIGKDGMTNSMAYCSQTPWLISGTIKDNVVFGEIFNKQKFDDVMKSCCLDKDIKAMTAGIRTDVGDGGFSLSGGQQQRIALARAIYSSSRYLILDDCLSAVDPETALYIYEECLCGPMMKGRTCIITSHNISLVTKRADWLVILDRGEVKSQGKPSDLIKSNEFLRESINNDSKNTTHNQIDLKRSTTSKKTKNGDPEGGNSQDEVCAEVENFEETKMEGSVKFSAYKWLADYFGGLGVVFVFTSSSILIHGITLSQGFWLRYWLDTGSSGSKSTWLYRIVEGHSNIYFLLTYIIIGLVSSFLTSGKVWIAIISGTNVTKKIFAKLLSSILYAKLRFHNVTPTGRIMNRFSKDMDIIDQQLIPNFEGLSYSVVVCLWIILLIGYVTPQFLLFAIPLCALYYTVCTLYLRASRELKRIDNINISPIHQLFAEAIKGVTTIRALADERRFITQSLVAIDRSNAPFFYLNMATEWITYRVDIIGTLVLFSSSVMIIMKASYLDAGLAGILLSNAFSFTETAQWIIKVFSSVELLMSSVERIKEYTDIPSESNGYISPPANWPQTGDVELKNLSLRYSPHSSKALDNVSFKVKAGTKVGIVGRTGAGKSSIIAAIYRLSDWENGTITIDNKDIKHIPLERLRNSISCIPQDPTLFDGTVRSNLDPFDRYSDVQIYGVLSKVGLIEECDELCLIFEQEQPNFSSHKLRNRFIDLNTVVKSGGSNLSQGQRQLLCLARSMLGARNIMLIDEATASIDYISDAKIQKTIRETMKNTTILTIAHRLRSVIDYDKILVMEMGRVKEYDHPYTLISDRNTIFYRLCRQSGEFENLFELAKVSFDNKR
What are the official names of this protein?
ABC transporter NFT1, New full-length MRP-type transporter 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CP51A_MOUSE
Sequence: MVLLGLLQSGGWVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPHIYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAKEYFQSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFTHAAWLLPAWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDSTYKDGRPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDLINGYFPTVNYTTMIHTPENPVIRYKRRSK
What is the function of this protein?
Sterol 14alpha-demethylase that plays a critical role in the cholesterol biosynthesis pathway, being cholesterol the major sterol component in mammalian membranes as well as a precursor for bile acid and steroid hormone synthesis (PubMed:21705796).  Cytochrome P450 monooxygenase that catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of sterols such as lanosterol (lanosta-8,24-dien-3beta-ol) and 24,25-dihydrolanosterol (DHL) in the form of formate, and converts the sterols to 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol and 4,4-dimethyl-8,14-cholestadien-3beta-ol, respectively, which are intermediates of cholesterol biosynthesis (PubMed:21705796).  Can also demethylate susbtrates not intrinsic to mammals, such as eburicol (24-methylene-24,25-dihydrolanosterol), but at a lower rate than DHL (By similarity).
What are the official names of this protein?
Lanosterol 14-alpha demethylase, LDM, CYPLI, Cytochrome P450 51A1, CYP51, Cytochrome P450-14DM, Cytochrome P45014DM, Cytochrome P450LI, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: RU1C_ANODA
Sequence: MPKYYCDYCDTYLTHDSPSVRKTHCTGRKHKDNVKFYYQKWMEEQAQHLIDATTAAYKAGKIAQNPFTAGPPKPNISIPPPTMNMPPRPGIIPGMPAGAPPLLMGPNGPLPPPMMGMRPPPMMVPTMGMPPMGLGMRPPVMSAAPPQLNPK
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DGTL1_RICBR
Sequence: MLASYASDPLKSRGRLYREIPTSYRNEFERDRDRIIHTNAFRRLQYKTQVFINHEGDHYRNRLTHSLEVSTVARSIANTLNLSSDLAETIALAHDLGHTPFGHAGERSLNECMKEHNGFSHNAQSLKILTLLEKRYAAYRGVNLTWEVLEGIVKHNGPISGEVNEYIEEYNSQNDLELNTYASAEAQIAALADDISYISHDLEDSIGAKIIDFNNLAELKYIDQHVFELKSKYKNISSSCLIYEVVRKLMHELITDLLWQTKTNINKEKITHIDEIRNLNYQIVDFTEKTNERIKEIKKFLHERVYKSNRITAISLKCTKIVQGLFKVYMEDVNLLPVNWKIQIDSNNPNSKARIIADYIAGMTDRFAIQEYNQLCSLNFNNI
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: SMG_XANAC
Sequence: MKESILDVLLYLFEHYFSEDADLVRDHDSLQNGLIQAGFSPAEISKAFDWLDALSEQRPSVARPHVDGPVRIYHGPELDKLDVDCRGFLLFLEQHRILDADQRELVLDRAMALDQDELDLDDLKWVVLMVLFNQPGAEAAYAWMETQMFLDEPEPVH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: PKHG3_MOUSE
Sequence: MPVSTALHQDGSQERPRSLVSTTSSSGSSRDSHSAMEEPTGSEASAQNGTGSPWDRHVPNSNNNSSGWLNMKGPLSPFNGRAGTSPAYHKLSYLGRVVREIVETERMYVQDLRSIVEDYLLKIIDTPGLLKPEQVSALFGNIESIYALNSQLLRDLDSCNSDPVAVASCFVERSQEFDIYTQYCNNYPNSVAALTECMQDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRVLKYHLLLQEIAKHFDEEEDGFEVVEDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEATFRVHRVRNDRTFFLFDKILLITKKRGDHFVYKGHIPCSSLMLIESTRDSLCFTVTHYKHSKQQYSIQAKTVEEKRSWTHHIKRLILENHHATIPQKAKEAILEMDSYYPSRYRCSPERMKKAWSSQDEVSSHVRQGRRQSEPGHTLFSRATLPSRQQGFEMPGLKGRRKSEPTRHLLRQLSEKARAVGMKHAGSAGALLDFGQPAHAQKQQPEAERAAREELEEEEELVEEEEQRQQSFSGSLEGLAGHDGSEKVPGPELPGSEEEEEEEESLAVAEQGKRHRESEGSKGCRRPSNRSPTSAEKRMSFESVSSLPEVETDPEPGAEQEAFAALEGPSTEEMPSDPEFPEALETQLHAPKGLLGVDNPAAVVDFVEPEGSEDLKPLSSEEEEEEEMEAAQEPESLLPPSVLDQASVIAERFASSFSRRSSLAIEDGKSSGLGTPRLISRSSSVLSLEGSDKGLARWSSIGDSLSNPPTPEVIIGADMVTDNGPSVNGTESPSAGSGCPTEQDRSSCKKKESALSTRDRQLLDKIKNYYENAEHHDAGFSIRRRESLSYIPKGLVRSSVSRFNSLPKPDSEPAAPVGYKRPGSSRPASWTLFDLPGPRTDKGDPAPITDAEFCPSSEIAKIWERMESSERSPRTGSGQSQANGFELQEPLFILEEHELGAITEESAVASPESASPTEQPSPAHLARELKELVKELSSSVQGELVTPLHPRIVQLSHVMDSHVSERVKNKVYQLARQYSLRIKNIKAARPPLQWEKVTPDQEEQVPSISGLPEEAGELSGGKARRKPVLSLLSYEQLVAQEHGTSKSSAAVETSPRRFSFSPSAVSPRTTSPGARSSARSPLSPFDTETFNWPDVRELCSKYTSHDKTAQVESSWPRSLLVNRSRSLPENIVEPPMSGKADRCCGLNTHRRLGDGEASQPPLPESPPQSQLNGGDALYVTADLTLENNQRVIIMEKGPHPSSTVGLEEDSGKESSSPVALKGQGQGFQASAEYQPKEHGPRDSADTNKQGRVRNLREKFQALNSVG
What is the function of this protein?
Plays a role in controlling cell polarity and cell motility by selectively binding newly polymerized actin and activating RAC1 and CDC42 to enhance local actin polymerization.
What are the official names of this protein?
Pleckstrin homology domain-containing family G member 3, PH domain-containing family G member 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with actin at the leading edge of polarized cells.
Protein: ENP1_TETCF
Sequence: NSVPTERLRMATLDVDPEASCSKLSTSPSNTSLTHRFLDNKFYLLVVIGEIVTEDHLRCAISDIERGIRSWDTDLISCNLDQELKLFVSRHSARFSADVRGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCCENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKANLTLFCPEEGDWKNANLKKHNLQDFINIKLNSVSILPEMEGLSEFTEYLSESVEVPSSFDVLEPPASGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSDRRSCFWKLVRHLDRVDSILLTHNGADNLPGVNSLLQRKIAELEEEQSQGSTANSDWMKNLISPELGVVFLNVPENVTNLQPNFRVRRNTEETCLTLQYLNKLCVKPEPLFRTVGNVIDPVILFQKMGVGRLEMYILNSVKGSKELQFFMQHWSSNNKAKTGLILPNGKDAEISFPYLTSISSLIVWHPANPSEKIVRALFPGNAPQYNILDGLEKLKHLDFLKHPVVTQKELIASSAAPTVKQAKLKQWSDSKESLKSNSRPSVGKGVKKDVKEETPELTKPTAVSHQEAVNEKPQKVEKKEKPVVKKERPRTELQSKPEEKDAKAKADAAKQELEEKMQKDEKLKSESKPKPLKEKIVKKEVKAKKPEEKKKEEKDVKKESAKPDRKEEKAVIKKEKVKKEEKPKKEEVKKDVKKDVKKEVKKKGN
What are the official names of this protein?
Electromotor neuron-associated protein 1.
What is the protein family that this protein belongs to?
To T.californica electromotor neuron-associated protein 2.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Note=Associated with membranes of intracellular organelles.