PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_PHOLL
Sequence: MSASGEVSTARDYIGHHLNNLQLDLRTFELVDPNSGGSATFWTLNIDSLFFSVVLGILFLYVFRKVAVNATSGVPGKLQTAIELIMGFVDNSVRDMYHGKSKVIAPLALTVFVWVLLMNVMDLLPIDFLPYIGEHFFGLPALRVVPTADVSVTLSMAIGVFVLILYYSIKMKGIGGFTKELTLQPFNHPLFIPINLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWLLSLPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCH2_PIG
Sequence: MDEAVGDLKQALPCVAEAPTVHVEVHQRSGSTAKKEDVKLNVRKLLNRHNIVFGDYTWTEFDEPFLTRNVQSVSIVDTELKVKDPQPIDLSTCTVALHVFQLNEGGPSSENLEEETENIIAANHWLLPAAEFHGLWDSLVYDAEVKSHLLDYVMTTLLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTRMFQMIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITERIDVAFVDRADIRQYVGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPTVTIEGFLQALSLAVDRQFEDRKKLSCV
What is the function of this protein?
Plays a key role in chromosome recombination and chromosome structure development during meiosis.  Required at early steps in meiotic recombination that leads to non-crossovers pathways.  Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.  Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation.  In males, required for efficient synapsis of the sex chromosomes and for sex body formation.  Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes.  Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes.  Plays a role in mitotic spindle assembly checkpoint (SAC) activation (By similarity).
What are the official names of this protein?
Pachytene checkpoint protein 2 homolog, Thyroid hormone receptor interactor 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. PCH2 subfamily.
Protein: ATP23_XENTR
Sequence: MEEKKIEQDELGYQLFPERGNGDRKKQGLLSKSLFTFNHKCQVMLKIALDTSPYAKLLLDAMKHTGCTVYKDRHFSCEECDGSVSGGFDAATSEIVLCQNNIHQQSHMNRVVTHELIHAFDHCRAHVDWFNNVRHLACSEIRAANLSGDCTLANELTRFKFGVKEHHKVCVRDRALRSILAVRNVSRETAEKAVDEVFDSCFNDHEPFGRIPHSKTDAKFAHRDFQNRDRYYANL
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23 homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
Protein: QUEC_ECOBW
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGFKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RL2A_YEAST
Sequence: MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L2-A, L5, Large ribosomal subunit protein uL2-A, RP8, YL6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH1_BACHK
Sequence: MKKGINRVVLVGTGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPAPTRVWKGSYEDCKDADLVVITAGLPQKPGETRLDLVEKNAKIFKQIVRSIMDSGFDGIFLIATNPVDILTYVTWKESGLPKERVIGSGTTLDSARFRYMLGEYFNIGPHNIHAYIIGEHGDTELPVWSHVSVGIQKLQTLLEKDNTYNQEDLDKIFINVRDAAYHIIERKGATYYGIGMSLLRVTKAILNDENSVLTVSAYLEGQYGQKDVYIGVPAVLNRGGVREILEVELSEDEELKFDHSVQVLKETMAPVL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_BACC7
Sequence: MTFEQLIPLIIMAFALGMDAFSVSLGMGMMTLKIRQILYIGVTIGIFHIIMPFIGMVLGRFLSEQYGDIAHFAGAILLIGLGFYIVYSSILENEETRTAPIGISLFVFAFGVSIDSFSVGLSLGIYGAQTVITILLFGFISMLLAWTGLFIGRHAKGMLGTYGEIVGGIILVGFGLYLLFPI
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDUI_XANC5
Sequence: MSLYCKTHYATHPDAIKGASNDALRELYLLDGLFVDDAVTLKYTHYERFVLGGAAPLGKTLELPRQTEPASAAGHPFLERRELGVLNVGAGTGTVTVDGTAYTLGPKDGLYVAMGSTDVSFASADAANPAKFYLASTPAHARFETKQLSIKDAVALERGALETSNERTIYQYIVPATCQSSQLLLGLTVLKPGSVWNTMPPHLHDRRSEVYFYFDLGANDRVYHFMGEPDAQRHIVIQNNEAVVSPPWSIHMGAGTSNYAFIWAMGGENLDYTDMHVLDICQLK
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: OBG_BACHK
Sequence: MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGRKSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVIVHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDLLFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKILEYEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECT2_MOUSE
Sequence: MIPTTILISAALLSSALAGPWANICASKSSNEIRTCDSYGCGQYSAQRTQRHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAINDGIRLSGRGFCVKIFYIKPIKYKGSIKKGEKLGTLLPLQKIYPGIQSHVHVENCDSSDPTAYL
What is the function of this protein?
Has a neutrophil chemotactic activity.  Also a positive regulator of chondrocyte proliferation.
What are the official names of this protein?
Leukocyte cell-derived chemotaxin-2, LECT-2, Chondromodulin II, ChM-II.
What is the protein family that this protein belongs to?
Belongs to the LECT2/MIM-1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE1_NITHX
Sequence: MATFHFDLVSPEKLTFSGDVDQVDVPGVEGDFGVLAGHAPVVAAIRPGILTITTGGTPQKIIVLGGLAEVSEKGLTVLADVATSIQELDRAQFADTIASMEAKLAEKEGSELDKAIERLDHFKSIQSQLNTTALH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain 1, ATP synthase F1 sector epsilon subunit 1, F-ATPase epsilon subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ZN285_HUMAN
Sequence: MIKFQERVTFKDVAVVFTKEELALLDKAQINLYQDVMLENFRNLMLVRDGIKNNILNLQAKGLSYLSQEVLHCWQIWKQRIRDLTVSQDYIVNLQEECSPHLEDVSLSEEWAGISLQISENENYVVNAIIKNQDITAWQSLTQVLTPESWRKANIMTEPQNSQGRYKGIYMEEKLYRRAQHDDSLSWTSCDHHESQECKGEDPGRHPSCGKNLGMKSTVEKRNAAHVLPQPFPCNNCGVAFADDTDPHVHHSTHLGEKSYKCDQYGKNFSQSQDLIVHCKTHSGKTPYEFHEWPMGCKQSSDLPRYQKVSSGDKPYKCKECGKGFRRSSSLHNHHRVHTGEMPYKCDECGKGFGFRSLLCIHQGVHTGKKPYKCEECGKGFDQSSNLLVHQRVHTGEKPYKCSECGKCFSSSSVLQVHWRFHTGEKPYRCGECGKGFSQCTHLHIHQRVHTGEKPYKCNVCGKDFAYSSVLHTHQRVHTGEKPYKCEVCGKCFSYSSYFHLHQRDHIREKPYKCDECGKGFSRNSDLNVHLRVHTGERPYKCKACGKGFSRNSYLLAHQRVHIDETQYTHCERGKDLLTHQRLHEQRETL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 285, Zinc finger protein 285A.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACEK_PSEPK
Sequence: MSQPWPAVEIARMILAGFDDYRDHFQRITLGARQRFEQARWQDIQQAAAARINLYEEKVAEVNGWLRQAFAAEVLLDVEQWPLVKNAYIHLIDPRLDDELAETWYNSLFCSLFSHDLISDGCMFIHTTRPSMRGRERAAQTRTYRLDGSLRNLLRAVFADYPFDMPYGDLEGDLARLEEQLRECLPDWVCKDPALAVELFVPVLYRNKGAYLVGRLYNSDEQWPLVIPLLHREGHGIEADALITDEAEVSIIFSFTRSYFMADVPVPAEFVNFLKRILPGKHIAELYTSIGFYKQGKSEFYRALINHLASSDDRFVMAPGVRGMVMSVFTLPGFNTVFKIIKDRFSPSKTVDRATVIDKYRLVKSVDRVGRMADTQEFADFRFPRSKFEPDCLAELLEVAPSTVALEGDTVLIRHCWTERRMTPLNLYLEQATEGQVLEALEDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEISFLTEVNFRHIPPPRYPEDEMSGEPWYSIGPHDVFPEEFPPFLFADMGQRRLFSRLHGELYDADYWKGLQAAIREGKVIDVFPYRRKAR
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_SHIB3
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_BRUC2
Sequence: MTDRTCLSIVLAAGEGTRMKSNLPKVLHRVAGLPLVCHVVNAVRGTGKSDVALVVGRGAEDVRSAVEKIAGPVSAFEQKERLGTAHAVLAAREAIARGYDDLLIVFGDTPLIEAQSLLAARERLAQGADLVVIGFRPASPHGYGRLIEEGGQLVAIIEEKEATDEQKKIGFCNGGLMALRGQHALALLDAVGNDNAKGEYYLTDIVAIAHGKGLNVTAIEVPVDNVIGINNRAELAEAETIWQNRKRRELMLSGVTLIAPETVFFSYDTVIEPDVVIEPNVFFGPSVHVASGALIHSFSHLEGAQVGEKAEIGPFARLRPGADLAEKSKVGNFCEVKNAKVGKGAKINHLTYIGDAVIGASSNIGAGTITCNYDGYNKFKTIIGDNAFIGSNSSLVAPVEIGDNAYIASGSVITADVPADALALGRARQETKEGRAKILREKYAAIKAAKSVSK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTK_ECO5E
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRYLQRLPSAIILQRASR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROB_SYNC1
Sequence: MRKDLLSQVKRIVIKVGSGVIFGQDGLDLDVIGSLSRDICALLSQGYEVVLVSSGAVATGKGELGIVGRPPTIPLKQAAAAIGQSRLMRAWKDAFRPCGRCVGQILLTRDDLANRRRFLNARNTLMTLLEYGVVPVINENDTVVVEEIRFGDNDNLSALTTSLAEADLLIILSDVNGLYDSNPKTNPAARKFSVIERITEDIEQMAGGAGSVVGTGGMATKVEAAKRATLYGVGTIIVDGRQAGVLPKLMAGEELGTFFLPVPQHMTARKHWISFSKASRGKLLVDEGARRAVAEKGKSLLPSGIFSIEGKFDRGDAVRICDAEGRVFAKGIASYSRQELERIMGRNSSEIEVVLGYKYGDEVVHRDNLVVKK
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BNZB_PSEP1
Sequence: MIDSANRADVFLRKPAPVAPELQHEVEQFYYWEAKLLNDRRFEEWFALLAEDIHYFMPIRTTRIMRDSRLEYSGSREYAHFDDDATMMKGRLRKITSDVSWSENPASRTRHLVSNVMIVGAEAEGEYEISSAFIVYRNRLERQLDIFAGERRDTLRRNTSEAGFEIVNRTILIDQSTILANNLSFFF
What is the function of this protein?
Catalyzes both the oxidation of benzene and toluene.  The beta subunit may be responsible for the substrate specificity of the enzyme.
What are the official names of this protein?
Benzene 1,2-dioxygenase subunit beta, Benzene 1,2-dioxygenase P2 subunit, Toluene 2,3-dioxygenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: ACKA_STRP8
Sequence: MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEHIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS24_ARATH
Sequence: MAERGVERGGDRGDFGRGFGGRGGGRGGPRGRGRRAGRAPEEEKWVPVTKLGRLVKEGKITKIEQIYLHSLPVKEYQIIDLLVGPSLKDEVMKIMPVQKQTRAGQRTRFKAFIVVGDSNGHVGLGVKCSKEVATAIRGAIILAKLSVVPIRRGYWGNKIGKPHTVPCKVTGKCGSVTVRMVPAPRGSGIVAARVPKKVLQFAGIDDVFTSSRGSTKTLGNFVKATFDCLQKTYGFLTPEFWKETRFSKSPYQEHTDFLLIPPGVKISEVVVDKSVE
What are the official names of this protein?
40S ribosomal protein S2-4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: VPC25_MYCTO
Sequence: MFLIDVNVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVWASFLRLTTNRRIFEIPSPRADAFAFVEAVNAQPHHLPTSPGPRHLVLLRKLCDEADASGDLIPDAVLGAIAVEHHCAVVSLDRDFARFASVRHIRPPI
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB25 (By similarity).
What are the official names of this protein?
Ribonuclease VapC25, RNase VapC25, Toxin VapC25.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: EF1D_RABIT
Sequence: MTTNFLVHEKIWFDKFKYDDAERSFYERMNGPVPGPSRQENGATVILRDIARARENIQKSLAGSSGPGASSGPGGDHSELAVRIASLEVENQNLRGVVQDLQRAVSKLEARLSALEKSSPTHRASAPQTQHVSPMRQVEPPAKKAAAPAEDDEDDDIDLFGSDEEEDKEAARLREERLRQYAEKKARKPALVAKSSILLDVKPWDDETDMARLEACVRSVQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFNKI
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-delta, EF-1-delta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: UDGA_THEMA
Sequence: MYTREELMEIVSERVKKCTACPLHLNRTNVVVGEGNLDTRIVFVGEGPGEEEDKTGRPFVGRAGMLLTELLRESGIRREDVYICNVVKCRPPNNRTPTPEEQAACGHFLLAQIEIINPDVIVALGATALSFFVDGKKVSITKVRGNPIDWLGGKKVIPTFHPSYLLRNRSNELRRIVLEDIEKAKSFIKKEG
What is the function of this protein?
Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP.  Can remove uracil from double-stranded DNA containing either a U/G or U/A base pair as well as from single-stranded DNA.
What are the official names of this protein?
Type-4 uracil-DNA glycosylase, TMUDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.
Protein: MALT_ECOHS
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: MNMG_CHLAB
Sequence: MWTHPINYDVIVVGAGHAGCEAAFCSAKMGASVLILSSNLDTIAKLSCNPAVGGIGKGHIVREIDALGGIMAEVTDQSGIQFRILNQTKGPAVRAPRAQVDKQMYHIHMKRLLESSPGLHIMQGTVESLLDNENVIQGVTTKEGITYLGKTVILSSGTFMRGLIHIGDLNFPGGRLGDPAATGLSLALKERGFPISRLKTGTPPRLLASSIDFSVTEEQPGDPGVGFVHRSEPFVPPLPQVSCYITHTTEKTKDIIAANIHRSALYGGRIEGIGPRYCPSIEDKIVKFADKERHHIFIEPEGIHTQEVYVNGLSTSMPFDVQYDMIRSVLGLENAIITRPAYAIEYDYVHGNVIYPTLESKLIEGLFLCGQINGTTGYEEAAAQGLIAGINAVNKVLKKPAFIPSRQESYIGVMLDDLTTQILDEPYRMFTGRAEHRLLLRQDNACLRLSHYGRDLGLLSKERYEIFENQKQIIEEEKLRLSKTFKKYGNSVVSLAKALCRPEVSYDTLREAFPEDIRDYGSTLNASLEMEIKYAGYIDRQKALIHSLSKSENMVIPEDIDYQSISSLSLEAREKLAKFTPRTIGSASRISGIACADIQVLMVAVKKHAHQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEP19_HUMAN
Sequence: MMCTAKKCGIRFQPPAIILIYESEIKGKIRQRIMPVRNFSKFSDCTRAAEQLKNNPRHKSYLEQVSLRQLEKLFSFLRGYLSGQSLAETMEQIQRETTIDPEEDLNKLDDKELAKRKSIMDELFEKNQKKKDDPNFVYDIEVEFPQDDQLQSCGWDTESADEF
What is the function of this protein?
Required for ciliation (PubMed:28625565, PubMed:28428259, PubMed:28659385).  Recruits the RABL2B GTPase to the ciliary base to initiate ciliation.  After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia (PubMed:28625565, PubMed:28428259).  Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly.  Involved in microtubule (MT) anchoring to the centrosomes (PubMed:28659385).
What are the official names of this protein?
Centrosomal protein of 19 kDa, Cep19.
What is the protein family that this protein belongs to?
Belongs to the CEP19 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, cilium basal body. Note=Associates with the mother centriole in early interphase. Localizes to spindle poles during mitosis, and to distinct foci oriented towards the midbody at telophase (PubMed:21399614). Localizes slightly apical to the subdistal appendage on the mother centriole, but below the distal appendage (PubMed:28625565, PubMed:28659385).