PharMolix/UniProtQA huggingface dataset:
Protein: ANM3_RAT
Sequence: MCSLAAGNGQGAELGPEPLELSDSGDDAGWEDEDADAEPAQGRQHTPCLFCDRLFRSAEETFSHCKLEHQFNIDGMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWDKDEYLKPVLEDDLLLQFDVEDLYEPVSAPFTYPNGLSENTSAVEKLKLMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVRTCSSTTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ
What is the function of this protein?
Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (PubMed:9642256, PubMed:15334060, PubMed:10899106).  May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity (By similarity).
What are the official names of this protein?
Protein arginine N-methyltransferase 3, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_BRUME
Sequence: MKRHAVWSSLFVVILAVLIDQGIKYLVESRMFYGQQIDLLPFLALFRTHNEGIAFSMLAWLHDGGLIAITLAVIAFVLYLWWTNAPERVFARYGFALVIGGAIGNLIDRVMHGYVVDYVLFHLPTWSFAVFNLADAFITIGAGLIILEEFLGWRRERISH
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACPS_METEP
Sequence: MILGIGTDLCDIRRIESSLERFGDRFTHRVFTDGERGKCDQRAARGPSYARRFAAKEACAKALGTGMSQGVFWRDMEVVNLPSGQPTLNLTGGAREQLARMVPAGHEARLHLTLTDEPPLAQAFVIIEAVPITATS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_BURCH
Sequence: MKPTVWHHLRLCPHGHPDETIDDAAIAVDETGTIAWLGALSALPHGYAHWQREDLHGAWVTPGLVDCHTHLVYGGTRADEFAQRLAGVSYEEIARQGGGIVSTVRATRAADETTLFVQAAARLQPLLAEGVTAIEIKSGYGLDLASERKMLRVARQLGERFPVTVYTTFLGAHALPPEYAGRADEYIDEVCDRMLPTLADEGLVDAVDVFCERIGFSLAQTERVFEAATRRGLPVKLHAEQLSNAGGTALAARYRALSADHLEFLDEAGIEAMKAAGTVAVLLPGAYYFIRETQLPPIDLLRKHGVPIALATDHNPGTSPLESLLLTLNMGCTLFRMTVPEVLQGVTRHAAAALGRADRHGALEVGRQADFAAWSVGSLAELAYWIGRPLCEQVVRGGTPVFRRMNG
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOQM_BACSU
Sequence: MKLRKVLTGSVLSLGLLVSASPAFATSPSAMVKENNIVQDEISVKELHTKYIYHHNINDFKNIEKDENGRNWYLKGIEYKDGWYVGKYQANY
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YoqM.
Protein: GATC_KOCRD
Sequence: MSAIDREQVAHLAELARIEMTDEELARVAGELELIVSSVASVSQAAGPDVPATSHPLPLQNVFREDVVGEMLTQEEALLNAPDSQDGKFRVPAILDGE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CLPP1_RHILO
Sequence: MSGLASLVPMVIEQSSRGERAFDIFSRLLRERIIFINGEINDDVSALVCAQLLSLESDNPDKEISLYINSPGGVVTSGFAIYDTMQYVSCPVSTVCMGFAASMGSFLLMAGTPGRRIALPNATILLHQPLGGFQGQASDIQRHAERIGKTKQRMAELYAQHCGRSYEEVERTLDRDHFMTAREAQTWGIVDHVFDTRKKAA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_YERPS
Sequence: MIEADRLISAAVINDEESIDRAIRPKLLTEYVGQPHVREQMEIFIQAAKQRGDALDHVLIFGPPGLGKTTLANIIANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVADLEHIVSRSAKCLGLELTPEGAHQLARRSRGTPRITNRLLRRVRDFAEVRADGAINGEVAMKALDMLNVDAEGFDFMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIATNHAYKHFGITREE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: QUEC_PSEA7
Sequence: MNQKKAVILLSGGLDSATVVAMAKADGYACYTMSFDYGQRHRAELQAAERVARQLGAIEHKVIGLDLNGMGGSALTDDSIAVPEAPSQGIPVTYVPARNTVFLSLALGWAEVLEARDIFIGVNAVDYSGYPDCRPEFVEAFERMANLATKAGVEGNGFRIQAPLQYLSKAQIIQAGVARGVDYGLTVSCYQADDQGRACGKCDSCRLRADGFAAAGIPDPTPYF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RUVA_ACIBC
Sequence: MIGCLIGEVFALEAPTVLLNVNGVGYEIDTPLSTFCQLQKGQKVTLWTHLVVREDAQQLYGFSDAQEKTIFRTLLKVNGVGPKMALGILSTLNVELLVHTIEHDDVNTLVKVPGVGKKTAERLMIELRDRFKTLAQGTSSAAALPQIQFVSNSPVAEAEAALQSLGYKPLEAQKAVAAVKADYTESADIIRAALKSMMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: AROC_CHLPB
Sequence: MIRYFTAGESHGPALSAIVEGLPAGLTVTPEDINKELARRQQGYGRGGRMKIETDKADVLSGIRFGKTIGSPVTLQVENRDWKNWTVKMARFDTPAEEIPAITVPRPGHADLTGMIKYGFEDIRPVIERASARETAARVAACALAKVFLRSAGIQIGSYVSSIGAAGKTAPSPRLHELLDAGAETLAEEADASSVRMLEKEHETHAIAAIDKAKEEGDTLGGIIELFITGVPMGLGSYVQHDRRLDAELAAALISIQAVKGVEIGTAFENARKPGSQVHDALFLRKGDGPERKTNRAGGIEGSMTNGQIIHLRAAMKPIATLMSPLQSFDIRSLDAHLSHIERSDTCAVPACSVIAEAVIAPVIANALLRKTGGDHLEEILERLEAYKADIAKNFQP
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: YCF3_PROM0
Sequence: MPSNQNRDNFIDKAFTVIAESIVKIMPIAEKEKKAYIYYRDGLAAQNNGDYSEALEYYKESLLLEENKIDRGETLKNMAIIYMSNGEEDLSIETYEKALVENPKQPSCLKNIGLIYEKRGRNAEQNGDLDQRDIWFDKAAEVWSKAVRLYPGGYLDIENWLKNSGRSSIDMYL
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ZFY_HUMAN
Sequence: MDEDEFELQPQEPNSFFDGIGADATHMDGDQIVVEIQEAVFVSNIVDSDITVHNFVPDDPDSVVIQDVVEDVVIEEDVQCSDILEEADVSENVIIPEQVLDSDVTEEVSLPHCTVPDDVLASDITSTSMSMPEHVLTSESMHVCDIGHVEHMVHDSVVEAEIITDPLTSDIVSEEVLVADCAPEAVIDASGISVDQQDNDKASCEDYLMISLDDAGKIEHDGSTGVTIDAESEMDPCKVDSTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNSSIRVPREKMVYMTVNDSQQEDEDLNVAEIADEVYMEVIVGEEDAAVAAAAAAVHEQQIDEDEMKTFVPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRLAKQKPKKKRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLAKKKYHCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELRKHMRIHTGEKPYQCQYCEYRSADSSNLKTHIKTKHSKEMPFKCDICLLTFSDTKEVQQHTLVHQESKTHQCLHCDHKSSNSSDLKRHVISVHTKDYPHKCEMCEKGFHRPSELKKHVAVHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKEVGLP
What is the function of this protein?
Probable transcriptional activator.  Binds to the consensus sequence 5'-AGGCCY-3'.
What are the official names of this protein?
Zinc finger Y-chromosomal protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLA1_DROME
Sequence: MSTKAELACVYASLILVDDDVAVTGEKINTILKAANVEVEPYWPGLFAKALEGINVKDLITNIGSGVGAAPAGGAAPAAAAAAPAAESKKEEKKKEEESDQSDDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1, Acidic ribosomal protein RPA2, RP21C.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: Y740_STRPQ
Sequence: MSTHLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLLALFYHHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGLQKWLRLDVNTATLVGIGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGSICWVAITLVSLAMQLSLGIW
What are the official names of this protein?
UPF0324 membrane protein SPs0941.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SUCC_HALLT
Sequence: MKLHEHQAKTIFADAGIPVPDSRLATTVDEALDAVDEIGYPAAIKAQVHVGGRGKAGGIKIATDRDEAEQYAEEILGMDLKGYTVDQILVEQGVDFVDELYVGVTMDRGEGQPVLMVSTEGGVNIEEVAEENPDAIAREHVDPAFGLHPYQARKVVYEAGVDADVALDVASILTTLYDLYEENDASEIEVNPVMITSDRDVIAADAVMNIDEDALFRHPDLAEMAEESYEDDLERKAGEYGFDYVRLSGNVGIIGNGAGLVMTTLDLVDYYGGKPANFLDIGGGAKAERVTKALDMVFSDENVDAVVFNIFGGITRGDEVAKGINEALEQFDEIPKKVVVRLAGTNAEEGMEILNTDLVEVEETLEDAVQRAVKNAEEVTQ
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: TFXB_RHILT
Sequence: MDFVQRFVIDRSFHLRYYSLDAYLYRAVDQVAWDADITHNRLFWDIWSAFMQPRSLVDAVETLSDYDPDEVAAAIEGMCESGIIEPVGLKDRQFDPLTVELSHVPQAWDYHLVSSRIDWINYLDGKDVKRQDLEQMDKHLSEEAVPSNFHKAANSRPKYDLPSLVPLTAFEFNNSASVAFGHEKAPLPNELSLDIITLLLNYAAAKTDTVNMYATGEHLRKAVPSGGARHPIEFYVVVGDEIAGIEAGVYHYNVRHHRLDAIEIASTSLKALQEASSVLPRSRSKPFGFAFIHTCRFERSMFRYREPRSYRVMQFDLGHIHANEVLAAKILGLDFSETFSVPESIVESVLTLDPFIESAMSAFVVHRHENHHD
What is the function of this protein?
The actions of the proteins TfxB, TfxD and TfxF are implicated in the processing of the inactive trifolitoxin (TfxA) precursor into the active peptide.
What are the official names of this protein?
Trifolitoxin-processing protein TfxB.
What is the protein family that this protein belongs to?
To E.coli McbC which is involved in the processing of microcin B17 (MCCB17).
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAM_HUMAN
Sequence: MEACVSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLARVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRSA
What is the function of this protein?
Cleaves peptide substrates after methionine, leucine, and norleucine.  Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin.  Promotes caspase activation and subsequent apoptosis of target cells.
What are the official names of this protein?
Granzyme M, Met-1 serine protease, Hu-Met-1, Met-ase, Natural killer cell granular protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Granules of large granular lymphocytes.
Protein: Y676_STRS7
Sequence: MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKMLEDFHAARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTFNALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMGRNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLNGITSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYASPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTETAVKKLELLMNDIGVTPKDRQVTLIARQKAELTGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTLAHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKELGNLKGSEAHSTVILTNEDKHALRQLGINVTFDPVYQHHKLYRSQSQTSS
What are the official names of this protein?
UPF0371 protein SZO_06760.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: LPTB_ECOL6
Sequence: MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLGEDFRL
What is the function of this protein?
Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Lipopolysaccharide export system ATP-binding protein LptB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS18_HALHL
Sequence: MGRFFRRRKYCKFTAEGVKEIDYKDLNTLKNYITDTGKIVPSRITGTSARYQRQLARAIKRARYLALLPYTDRH
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TAX_HTL3P
Sequence: MAHFPGFGQSLLYGYPVYVFGDCVQADWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVVSSALQYLIPRLPSFPTQRTTRTLKVLTPPTTATTPKVPPSFFHAVKKHTPFRNNCLELTLGEQLPAMSFPDPGLRPQNVYTIWGCSVVCLYLYQLSPPMTWPLIPHVIFCHPEQLGAFLTRVPTKRLEELLYKIFLSTGAIIILPENCFPTTLFQPTRAPAIQAPWHTGLLPCQKEIVTPGLIWTFTDGSPMISGPCPKEGQPSLVVQSSTFIFQQFQTKASHPAFLLSHKLIQYSSFHSLHLLFEEYSTVPFSLLFNEKGANVSDDEPRGGPQPPTGGQIAESSV
What is the function of this protein?
Transcriptional activator that activates both the viral long terminal repeat (LTR) and cellular promoters via activation of CREB, NF-kappa-B, SRF and AP-1 pathways.  Binds to two 21 bp repeat elements located within the LTRs, referred to as Tax-responsive element (TRE).  Binding to TRE requires the interaction with CREB1 and CREBBP.  Activation of NF-kappa-B leads to up-regulation of the expression of gene promoters containing NFkB motifs like IL8 or BCL2L1.  Inhibits the action of p53/TP53 and MYCB.  All these functions could lead to the possible occurrence of lymphoproliferative disorders.  Required for viral replication.
What are the official names of this protein?
Protein Tax-3, Trans-activating transcriptional regulatory protein of HTLV-3.
What is the protein family that this protein belongs to?
Belongs to the deltaretrovirus Tax protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Shuttles from the nucleus to the cytoplasm. Found predominantly in the nucleus, with some cytoplasmic speckles.
Protein: PSAJ_EMIHU
Sequence: MSKDLLKYLSTAPVLLTAWMSLTAGMIIEIQRFFPDSLSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LIPB_MYCPA
Sequence: MIDSIRSSRALIDVRRLGTVDYRAAWQQQRDLADARVAGGPDTLLLLQHPAVYTAGRRTEPHERPLDGTPVVDTDRGGKITWHGPGQLVGYPIIGLAEPLDVVDYVRRLEEALIKVCADLGLDTVRVPGRSGVWVPGDAGRPDRKVAAIGVRVSRATTLHGFALNCDCELGAFNAIVPCGISDAGVTSLTAELRRPVAVDDVVTSVADAVCDALDGVLPVREHSPGARVASAM
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_SPIOL
Sequence: MAMAATSSTQTNLFLKAPFNPQQNCQQTHFLPLNFKIRNPISRITCSATPTATAVSTTTKIDQRSEERVFNFAAGPAVLPENVLQKAQSELLNWRGSGMSVMEMSHRGKEFTSIIDKAEADLRTLLNIPSDYTVLFLQGGASTQFSAIPLNLCTPDSAVDYIVTGSWGDKAAKEAAKYAAVSSIWSGKSDNYVRIPNFDGSEFVQNSQARYLHICANETIYGVEFKKYPVPANPDGFLVADMSSNFCSKPVDVTKFGLIYAGAQKNVGPSGVTIVIVRNDLIGNAQKMTPVMLDYKIHADNKSLYNTPPCYGIYMCGLVFEDLLNQGGLVEVEKKNKAKAQVLYDAIDESNGFYKCPVEKSVRSLMNVPFTLEKSELEGDFIKEAAKEKMVALKGHRSVGGMRASIYNAMPLAGVEKLVAFMKEFQAKHA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, chloroplastic, PSAT, Phosphohydroxythreonine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: C27C1_HUMAN
Sequence: MQTSAMALLARILRAGLRPAPERGGLLGGGAPRRPQPAGARLPAGARAEDKGAGRPGSPPGGGRAEGPRSLAAMPGPRTLANLAEFFCRDGFSRIHEIQQKHTREYGKIFKSHFGPQFVVSIADRDMVAQVLRAEGAAPQRANMESWREYRDLRGRATGLISAEGEQWLKMRSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGVATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFIPKPWREFCRSWDGLFKFSQIHVDNKLRDIQYQMDRGRRVSGGLLTYLFLSQALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQTNAVHAKTHGLLTPGGPIHVRFVNRK
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes the 3,4 desaturation of all-trans-retinol (also called vitamin A1) to all-trans-3,4-didehydroretinol (also called vitamin A2) in the skin.  Desaturates with lower efficiency all-trans retinal and all-trans retinoic acid.  Forms minor amounts of 3-hydroxy and 4-hydroxy all-trans-retinol derivatives.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule.  Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
What are the official names of this protein?
Cytochrome P450 27C1, All-trans retinol 3,4-desaturase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
[Isoform 2]: Mitochondrion membrane; Peripheral membrane protein.
Protein: RS12_BUCAI
Sequence: MATVNQLVRKPRVRKVIKSNVPALGKSPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTAYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHIVRGSLDCAGVKERKQGRSKYGVKKPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.