PharMolix/UniProtQA huggingface dataset:
Protein: RL151_PLAVT
Sequence: MRNRAVLFGLFFIGYSSCVFHATPTRASLVENPDVESTHVEQWDSNGKRLLQVDGPKRILAEERGMSEGILPAAEAVEKTKVSEKAVPRASLGSKLNPMTWPKRILHKLKLWYARFLHWLLRKATVDEKTIDRSMMNGLTPSNLKRVKNDILHYSSSVPHDKIEIETDYDSYVEHFFGQFKGLDKDPPVFEMDKWNNLEKEMTKAEGYLKRRALNTVSRNIDKGLSNEQLISLDVSPFVYMRLLEKRGVFKDVENNKDKIDQLKDYIKAYKEHLMVEQ
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 151.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host endoplasmic reticulum membrane.
Protein: GLYA_LIMF3
Sequence: MEYAGKDAQLWAAIGREEQRQEGTIELIASENIVSKEVAAAQGSVLTNKYAEGYPGKRYYGGCQFIDQVEQLAIDHAKELFGAAYANVQPHSGSQANMAVYQALLKPGDTILGMGMDAGGHLTHGSKVNFSGKLYHTYGYELSPETEELDYDAILAQAKEIQPQLIVAGASAYSQIIDWDKFRQIADEVGAYLMVDMAHIAGLVATGYHPNPVPVADVVTTTTHKTLRGPRGGMILSKSEELGKKLNSAVFPGTQGGPLEHVIAGKAQAFYEDLQPAFKDYIGQVVKNAAAMAEVFNESETIRVVTGGTANHLLVLDLTKTGLTGKDAQALLDSVMITTNKEAIPNDQRSPFVTSGLRVGTPAITSRGFKEDDAKQVASLIIKALDNADDQTILAEVKEAVHALTQAHPVD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAD_HUMAN
Sequence: MFQIPEFEPSEQEDSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQEQPTSSSHHGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ
What is the function of this protein?
Promotes cell death.  Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX.  Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity).  Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
What are the official names of this protein?
Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2-L-8, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Cytoplasm. Note=Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm.
Protein: BGL27_ORYSJ
Sequence: MRWLLLALFLVALVSNGAAVHGAFNRFSFPEDFIFGTGSAAYQYEGAVNEGGRGPSIWDTYAHIPGKVEDGSNGDVAVDFYHRYKEDLNFVTDMNMDAFRFSIAWSRILPNGTISGGINKEGIAFYNSLINEVISRGLKPFVTIFHFDTPQALEDKYRSFLSENIVKDFVDYADVCFREFGDRVKSWNTFNEPMIFCAGGYGSGTKAPGRCSPYVSKKCAPGDSGNEPYVAGHNLLLAHAEAVRLYRQKYQATQKGQIGITQVSHWFVPYSDAAADKHAVRRSLDFMYGWFMDPIVFGDYPGTMRKLVGDRLPKFTAEQSELVKGSYDFIGLNYYTTNYAKSVLRRPSKLKPAYATDNWVNQTAYRNGVPIGPPAFTKIFFTYAPGLRELLLYTKRKYNDPDIYIAENGTDEANNSTIPIAEALKDDNRISFHYQHLRFTQLAIKEGVKVKGYFTWTFMDDFEWGDGYTGRFGLIYVDRETLKRYRKKSSYWFADFLKR
What are the official names of this protein?
Beta-glucosidase 27, Os8bglu27.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: GP1BB_PAPCY
Sequence: MGSGPRGAVSLLLLMLAPPSCPAADCPAPCSCAGTLVDCGRRGLTWASLPTSFPVHTTELVLTGNNLTALPSGLLDALPAVRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVAPPAVRGRLLPYLAEDDVRAACAPGPLCWGALAAELALLGLGLLHALLLVLLLCRLRRLRARARARARAALRLSLTDPLVAEQDGTDES
What is the function of this protein?
Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.
What are the official names of this protein?
Platelet glycoprotein Ib beta chain, GP-Ib beta, GPIb-beta, GPIbB, Antigen CD42b-beta.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AOXB_MOUSE
Sequence: MPCPAQISDDLEFFVNGRKVTEKNVDPEVTLLAFLRKNLCLTGTKDACGTGGCGACTVMVSQHDPVCKKTRHFSVMACLVPLCSLHGAAVTTVEGVGSIKTRLHPVQERIAKSHGTQCGFCTPGMVMSIYTLLRNHPQPSEEQLMEALGGNLCRCTGYRPILESGRTFCMEPDGCPQKGTGQCCLDQKESDSSGSKSDICTKLFVKDEFQPLDPTQELIFPPELLRMAENPEKQTLTFYGERITWIAPGTLQELLVLKAKYPEAPLISGNTALGPAMKSQGHFYPVLLSPARIPDLRMVTKTSGGLTIGACCSLAQVKDILAESISELPQEKTQTYRALLKHLRSLAGQQIRNMASLGGHVISRHCYSDLNPILSVGNTTLNLLSEEGPRQIPLSGHFLAGLASADLKPEEILGSVYIPHSQKREFVSAFRQAQCHQNALPDVNAGMRVLFREGTDVIEELSIAYGGVGPTTVSAQRSCQQLLGRRWNALMLDEACRLLLDEVSLPGSALGGKVEFRRTLIVSLFFKFYLEVLQELKADQKLPPESTDSQRYPEIADRFLSSLGDFQVTLPRGVQTYQRVDSHQPLQDPVGRPIMHLSGLKHATGEAVFCDDIPRVDKELFMALVTSTRAHARIISIDSSEVLDLPGVVDVITAEDIPGNNGEEDDKLLAVDKVLCVGQVICAVVAETDVQAKRATEKIKITYEDLKPVIFTIEDAIKHNSFLCPEKKLEQGNIEEAFENVDQVAEGTVHVGGQEHFYMETQRVLVIPKTEDKELDMYVSTQDPAHVQKTVSSTLNIPISRITCHVKRVGGGFGGKVGRPAVFGAIAAVGAVKTGHPIRLVLDREDDMLITGGRHPLFAKYKVGFMNSGRIKALDIECYINGGCTLDDSELVTEFLVLKLENAYKIRNLRLRGRACMTNLPSNTAFRGFGFPQGALVTESCITAVAAKCGLPPEKIREKNMYKTVDKTIYKQAFNPDPLIRCWNECLDKSSFHIRRTRVDEFNKKSYWKKRGIAIVPMKFSVGFAATSYHQAAALVHIYTDGSVLVAHGGNELGQGIHTKMLQVASRELKIPLSYLHICETSTTTVPNTIATAASVGADVNGRAVQNACQILLKRLEPVIKKNPEGTWRDWIEAAFEKRISLSATGYFRGYKAFMDWEKGEGDPFPYYVYGAACSEVEIDCLTGAHKKIRTDIVMDACCSLNPAIDIGQIEGAFIQGMGLYTTEELLYSPEGVLYSRSPDKYKIPTVTDVPEQFNVSLLPSSQTPLTLYSSKGLGESGMFLGSSVFFAIVDAVAAARRQRDIAEDFTVKSPATPEWVRMACADRFTDMIPRDDPKTFKPWSIPIA
What is the function of this protein?
Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as phthalazine, as well as aldehydes, such as benzaldehyde and retinal.  Cannot use hypoxanthine as substrate.
What are the official names of this protein?
Aldehyde oxidase 2, Aldehyde oxidase homolog 3, Azaheterocycle hydroxylase 2.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T4A_PARTE
Sequence: MARSLTILAIVFAVATARVTKSESPKEILAQVNKDSFGNSILSVLQLQLATGGPVGEIQILLNNIASQLNGDQKKADKVHESDTVAFEKIIADLEQEIAYHQTQIVALSNLRDSTTEALGEAEVEVRVVTSDIANNEKSFADESATRQSQHDTWVRKDAEHVDQMEAIDEASKIVQHLQAGVAFAQLKSRFEKVQAKLMESKHALFKPLINALTQLASKVDNKSIIKILELLAQIRQQLVASRASLLATEERQAANWEVQSSHLQEEHKRLVERKAFLENSIVQFKVTIQEAVEDLEDQTLFLEDAEDSLAIQERWAAEQESQYEAQTFEREQQLEVVERLQEVLTQKLSAASEFLQVREEVF
What is the function of this protein?
Structural protein that crystallize inside the trichocyst matrix.
What are the official names of this protein?
Trichocyst matrix protein T4-A, Secretory granule protein T4-A, TMP 4-A.
What is the protein family that this protein belongs to?
Belongs to the TMP family.
What are the subcellular locations of this protein?
Trichocyst. Note=These are architecturally complex secretory storage granules-docked at the plasma membrane, ready to rapidly respond to an exocytotic stimulus.
Protein: CARB_THEP3
Sequence: MPKYKDINKVLVIGSGPIIIGQAAEFDYSGTQACKSLKEEGVQVVLVNNNPATIMTDTDIADIVYIENPTVSVVEKIIAKERPEGILATLGGQTGLNLAVKLKEEGILDKYNVKLLGTSFESIKTAEDRELFKRKMQEIGEPVAESVTVTNIEDALKFAKNYGYPLIIRPAYTLGGTGGGIAHNDEELISIVDLGLKKSMVGEVLVEKSLYGWKEIEFEVMRDAADNCITICSMENFDPVGVHTGDSIVVAPTQTLSDYEYQMLRSASIKIIKALKIEGGCNIQFALDPKSHKYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAIGLRLDEIKNPVTGKTTAFFEPALDYVVTKIPRWPFDKFYTTDRKIGTQMKATGEVMAIERSFEASLLKAVRSLEIKAYGLRLNNVKAMKTEEILKGISVPNDMRLFYIAEALRRDIDIDYINEVTKIDKWFLNKLLNIVNMEREVEKSELSEGILKKAKRMGFSDREIATIKGIKEEDVRMLRKQHGIYPSYKMVDTCAAEFESVTQYIYSTYGEEDEVEIHDMPKVIVIGSGPIRIGQGIEFDYCSVKALWALREAGIKSIIINNNPETVSTDFDTGDRLYFEPITLEDVLNIYEKEKPLGVMVMFGGQTAINLTEGLVKNRVKILGTSYESIDISEDREKFSKLLRELNINQPKGDYALTVEDAKDIALKLGFPLLIRPSYVIGGQSMEKVNTLQEIIDYVSNATQVSPGRPILIDKYIDGREVEVDAVSDGECVLIPGIMEHIERAGVHSGDSFSIYPARNLSEREINTIIEYTERISKALNVKGLINIQFAVKEGTVYVLEVNPRASRTVPIMSKATGVPMVKLAVEVALGKKLKELGYKSGLWPQTPYTVVKAPVFSMEKLTDAEVSLGPEMKSTGEIMGIDLSYEGALYKALEGAGLKIPKKGKILLSIAERDFQEVPSLVEKLQSLGYEIYATYRTGKYLSLMGIHVNVISLDNAIKLLKDGYFDAVINTPTKGKKPDNTGFKLRRTAVEYRIPLFTSMDTIKAALNAVAKVNVNGLSILSINEYEEIQKDNVKNLVL
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RABK3_DICDI
Sequence: MDNKRKLLKELYMGRPIFQWGYSIALDFHYKEIIIDNETVSFQVSTNLLWNTHGSAFGDSKIYYRDVDCCVLCFGIHNEQSFNNLIYWIKELEANTLVDEKVPFVLIGTKSDIERTEKSISKERIEQWCKNKQKNSINISTLHHRMGY
What are the official names of this protein?
Ras-related protein RabK3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: RECR_MYXXD
Sequence: MTPDPLNRLVAQLAKLPGIGEKTAQRLAFHILRAPGEYAAELSQAIREVKEKVHLCVRCFSLTDAETCNFCRDARRDERVLCVVETFADLMALERTREFKGRYHVLHGVLSPLEGVGPDQLRIRELLERLNDSRVEELILATNPDVEGEATALYLTRLLKPMGLRVTRIAQGLPMGGDLEFADQATLAKALSARRDL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: URE3_AGRVS
Sequence: MNLSPREKDKLLISMAAMVARRRLERGVKLNYPEAIALISDFVVEGARDGRAVSELMEAGAHVITRDQVMDGIAEMIHDVQVEATFPDGTKLVTVHEPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOWR_DROYA
Sequence: MSFAEKITGLLARPNQQDPIGPEQPWYLKYGSRLLGIVAAFFAILFGLWNVFSIITLSVSCLVAGIIQMVAGFVVMLLEAPCCFVCFEQVNVIADKVDSKPLYFRAGLYITMAIPPIILCFGLASLFGSGLIFGTGVVYGMMALGKKASAEDMRAAAQQTFGGNTPAQTNDRAGIVNNAQPFSFTGAVGTDSNV
What is the function of this protein?
A calcium channel that regulates synaptic endocytosis and hence couples exo- with endocytosis.  Required in the nervous system and necessary in photoreceptor cells (By similarity).
What are the official names of this protein?
Calcium channel flower.
What is the protein family that this protein belongs to?
Belongs to the calcium channel flower family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Upon fusion of the synaptic vesicle with the presynaptic membrane, protein is present in the periactive zones, where endocytosis is known to occur.
Protein: MRM2_YEAST
Sequence: MILVYNRIRSIISSSLGRIHVRYNSNSQNRWLNRQLKDPYTKEAKVQNLRSRAAFKLMQIDDKYRLFSKNRTDQRILDLGYAPGAWSQVARQRSSPNSMILGVDILPCEPPHGVNSIQANILAKRTHDLIRLFFSKHFQLNRHDDLHKDHGYFQNMLEEELTHVKDTELYREIFTSDDIYETPNTNSTLIEREKFPVDVIISDMYEPWPQTTGFWNNITNQAYFRMANTSGVSIRDHYQSIDLCDAALVTAIDLLRPLGSFVCKLYTGEEENLFKKRMQAVFTNVHKFKPDASRDESKETYYIGLKKKRNVDKLDVFSNS
What is the function of this protein?
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 2791 (Um2791) in the 21S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
What are the official names of this protein?
rRNA methyltransferase 2, mitochondrial, 21S rRNA (uridine(2791)-2'-O)-methyltransferase, 21S rRNA [Um2791] 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNC_MAGMM
Sequence: MNAQREPSGLERLEQALDYRFTQSDLLQLALTHRSAPLDGSKAGEVVATTHNERLEFLGDSVLNLIVSHRLYKRFGEVPEGQLSQWRAMLVNTRSLSEVAKDLELGRYLRMGRGEAKSGGREKYSILGNALEALLGAIYLDGGFEAAERVVDRLFAHQVAGIEPEQQGKDYKTLLQEYLQARGEALPIYAVLSAEGPPHERVFVVSCHPREQLCGHGQGRSKREAEQHAAQQALELLIESENEHHD
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLNK_MOUSE
Sequence: MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMDKIKKLKVKGPPSVPRRDYALDSPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEETGDDSYEPPPAEQQTRVVHPALPFTRGEYVDNRSSQRHSPPFSKTLPSKPSWPSAKARLASTLPAPNSLQKPQVPPKPKDLLEDEADYVVPVEDNDENYIHPRESSPPPAEKAPMVNRSTKPNSSSKHMSPPGTVAGRNSGVWDSKSSLPAAPSPLPRAGKKPATPLKTTPVPPLPNASNVCEEKPVPAERHRGSSHRQDTVQSPVFPPTQKPVHQKPVPLPRFPEAGSPAADGPFHSFPFNSTFADQEAELLGKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVAFFNKRVYNIPVRFIEATKQYALGKKKNGEEYFGSVVEIVNSHQHNPLVLIDSQNNTKDSTRLKYAVKVS
What is the function of this protein?
Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development.  Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK.  Modulates AP1 activation.  Important for the activation of NF-kappa-B and NFAT.  Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes.  However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling.  May be required for the RAC1-JNK pathway.  Plays a critical role in orchestrating the pro-B cell to pre-B cell transition.  May play an important role in BCR-induced B-cell apoptosis.
What are the official names of this protein?
B-cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Lymphocyte antigen 57, Src homology 2 domain-containing leukocyte protein of 65 kDa, Slp-65.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=BCR activation results in the translocation to membrane fraction.
Protein: FPG_ACTP7
Sequence: MPELPEVETSLRGVEPYLHGKIIKQIVVRTQKLRWAVSDELQHMQGAKIVALSRRAKYLILHTTQGDILIHLGMSGSLGILQENQQPAGKHDHVDLITQDGMVLRYNDPRKFGCWLWTKNAEQHELITRLGPEPLSESFTAAYLFARSRNKTVAVKNFIMNNDIVVGVGNIYACESLFMAGLHPELAAQNLTEKQCERLVKVIKEVLAKAIIQGGTTLKDFIQPDGKPGYFAQVLQVYGRKGEACNDCGTIIEAKVIGQRNSYFCPHCQILPR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: NUOH_RICRO
Sequence: MLELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNADKILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEVSMGLVIITVLLTTGTLNLSEIIEAQRTIPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALFFLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTLFWVVLVSSVLVYTDNLPSI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROA_ENTFA
Sequence: MQLRTNVKHLQGTLMVPSDKSISHRSIMFGAISSGKTTITNFLRGEDCLSTLAAFRSLGVNIEDDGTTITVEGRGFAGLKKAKNTIDVGNSGTTIRLMLGILAGCPFETRLAGDASIAKRPMNRVMLPLNQMGAECQGVQQTEFPPISIRGTQNLQPIDYTMPVASAQVKSAILFAALQAEGTSVVVEKEKTRDHTEEMIRQFGGTLEVDGKKIMLTGPQQLTGQNVVVPGDISSAAFFLVAGLVVPDSEILLKNVGLNQTRTGILDVIKNMGGSVTILNEDEANHSGDLLVKTSQLTATEIGGAIIPRLIDELPIIALLATQATGTTIIRDAEELKVKETNRIDAVAKELTILGADITPTDDGLIIHGPTSLHGGRVTSYGDHRIGMMLQIAALLVKEGTVELDKAEAVSVSYPAFFDDLERLSC
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM44_HUMAN
Sequence: MGEAPSPAPALWDWDYLDRCFARHRVCISFGLWICASSCWIAAHALLLYLRCAQKPRQDQSALCAACCLLTSLCDTVGALLARQLTIQVFTGAYLAAIDLVNFMFILFPVCGSKFKSNSDREARERKRRRQLRASVFALALPLSLGPCWALWVAVPKASATIRGPQRRLLASLLQENTEILGYLLGSVAAFGSWASRIPPLSRIAPPPTLGITTQHEIWRGQMSKPSQSPSRSPSGHWRAAAQRQVLGTEMCRGKTFPSIHLWTRLLSALAGLLYASAIVAHDQHPEYLLRATPWFLTSLGRAALDLAIIFLSCVMKSKMRQALGFAKEARESPDTQALLTCAEKEEENQENLDWVPLTTLSHCKSLRTMTAISRYMELTIEPVQQAGCSATRLPGDGQTSAGDASLQDPPSYPPVQVIRARVSSGSSSEVSSINSDLEWDPEDVNLEGSKENVELLGSQVHQDSVRTAHLSDDD
What are the official names of this protein?
Transmembrane protein 44.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PTH1R_BOVIN
Sequence: MGAARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPADIMESDKGWASASTSGKPKKEKPSGKLHPESEEDKEVPTGSRPRGRPCLPEWDHILCWPLGAPGEVVAMPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGTALDEAERLTEEELRAIAQAPPPPAAAAGYVGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAIFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRTGLGLPLSPRLLPAATTNGHPPLPGHTKSGSPALQATPPAVAAPKEDGFLNGSCSGLDEEACAPERPPVLLQEEWETVM
What is the function of this protein?
Receptor for parathyroid hormone and for parathyroid hormone-related peptide.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADE_METJA
Sequence: MLWGESMEEIVNKITKFIREKVEEANANGVVVGLSGGIDSSVTAYLCVKALGKDKVLGLIMPEKNTNPKDVEHAKMVAENLGIKYIISDITDILKAFGAGGYVPTREFDKIADGNLKARIRMCILYYFANKYNLLVAGTSNKSEIYVGYGTKHGDIACDIRPIGNLFKTEVKKLAKYIGVPKEIIEKPPSAGLWEGQTDEEELDIKYETLDTILKLYEKGKTPEEIHKETNIPLETINYVFDLIKKNEHKRTLPPTPEI
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: EFP_YERP3
Sequence: MASYYSNDFRPGLKIMFEGEPYAVESSEFVKPGKGQAFARVKMRRLLTGGRVEKTFKSTDSLEGADVNDMNLTYLYNDGEFWHFMNNETYEQLQADAKAVGDNGKWLIDQAECIVTLWNGQPIAVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQVGEIIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUNB_DROSE
Sequence: MQNWETTATTNYEQHNAWYNSMFAANIKQEPGHHLDGNSVASSPRQSPIPSTNHLEQFLKQQQQHQQQPMDTLCAMTPSPSQNDQNSLQHYDANLQQQLLQQQQYQQHFQAAQQQHHHHHHLMGGFNPLTPPGLPNPMQHFYGGNLRPSPQPTPTSASTIAPVAVATGSSEKLQALTPPMDVTPPKSPAKSSQSNIEPEKEHDQMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKNYKCKTCGVVAITKVDFWAHTRTHMKPDKILQCPKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKYGHKPGMVLDEDGTPNPSLVIDVYGTRRGPKSKNGGPIASGGSGSGSRKSNVAAVAPQQQQSQPAQPVATSHLSAALQGFPLVQSNSAPPAASPVLPLPASPAKSVASVEQTPSLPSPANLLPPLASLLQQNRNMAFFPYWNLNLQMLAAQQQAAVLAQLSPRMREQLQQQNQQQSDNEEEDQDDEYERKSVDSAMDLSQGTPVKEDEQQQQPQQPLAMNLKVEEEATPLMSSSNASRRKGRVLKLDTLLQLRSEAMTSPEQLKVPSTPMPTASSPIAGRKPMPEEHCSGTSSADESMERPHVRQANTSASSTASSSGNSSNASSNSNGNSSSNSSSNGTTSAVAAPPSGTPAAAGAIYECKYCDIFFKDAVLYTIHMGYHSCDDVFKCNMCGEKCDGPVGLFVHMARNAHS
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOD_BACAN
Sequence: MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICHAVETMMGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVKWDAPDGWIEKVKEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYDRFDFDIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.