PharMolix/UniProtQA huggingface dataset:
Protein: ACBG1_RAT
Sequence: MPRSSEAGYCCLSRDSNMPDSRDDQQQGASMGTSPDNSQTSSLIDGRTLSKESPSHGLELSAPEKARAASLDASEEALWTTRADGRVRLRLEPFCTQLPYTVHQMFYEALDKYGNLSALGFKRKDKWERISYYQYYLIARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAHDCRANVIVVDTQKQLEKILKIWKDLPHLKAVVIYQEPPPKKMANVYTMEELIELGQEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFADPDALKGTLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFAKCQKNFYGAAPMTAETQRFFLGLNIRLYAGYGLSESTGPHFMSSPYNYRLYSSGRVVPGCRVKLVNQDADGIGEICLWGRTIFMGYLNMEDKTHEAIDSEGWLHTGDMGRLDDDGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLNPETSEPTDNLTEQAVEFCQRVGSKASTVSEIVGQKDEAVYQAIHEGIQRVNANAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKDIIDSFYQEQKQ
What is the function of this protein?
Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.  Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase ACSBG1, Acyl-CoA synthetase bubblegum family member 1, Gonadotropin-regulated long chain acyl CoA synthetase, GR-LACS.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Microsome. Endoplasmic reticulum. Cell membrane.
Protein: Y1181_STAA9
Sequence: MNLIPRTSIVVYLKHMKHERQIRKYGHIVHSNRDRKFVIMYVNEQDVDQIVHKLMQLKYVRHIDGSPYKYLKKTYEKEKHEIYN
What are the official names of this protein?
UPF0298 protein SaurJH9_1181.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPT6_ARATH
Sequence: MQQLMTLLSPPLSHSSLLPTVTTKFGSPRLVTTCMGHAGRKNIKDKVVLITGTTGTGKSRLSVDLATRFFPAEIINSDKMQIYKGFEIVTNLIPLHEQGGVPHHLLGQFHPQDGELTPAEFRSLATLSISKLISSKKLPIVVGGSNSFNHALLAERFDPDIDPFSPGSSLSTICSDLRYKCCILWVDVLEPVLFQHLCNRVDQMIESGLVEQLAELYDPVVDSGRRLGVRKTIGVEEFDRYFRVYPKEMDKGIWDLARKAAYEETVKGMKERTCRLVKKQKEKIMKLIRGGWEIKRLDATAAIMAELNQSTAKGEGKNGREIWEKHIVDESVEIVKKFLLEV
What is the function of this protein?
Involved in cytokinin biosynthesis.  Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP.
What are the official names of this protein?
Adenylate isopentenyltransferase 6, chloroplastic, AtIPT6, Adenylate dimethylallyltransferase 6, Cytokinin synthase 6.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPXH_NITOC
Sequence: MATFFISDLHLGTGKTEIQLRAIEFLSQEAPYGDALYILGDLFDYWIGDDAPTAEGLAIITALRRLADVGVTLHFLSGNRDFLVGQVFSQASGCQILSDPAIIDLYGVPTLLMHGDTLCTDDVAYQRARARLRRPAILRTYLALPKSWRRAVAQRLRRQSQAHVQHQPLTIMDVNQTAVETALRIHGVKQLIHGHTHRPAVHHFTVDGHPRQRIVLGDWDRGKSALSCTPEGFHFSDSRILEPRFGNLQG
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IXTPA_DICT6
Sequence: MDKRIIVLATKNEGKVREILEILSEYKDQIKTLKELEFDMDLPEETGKSYEENAFIKAKYVAEITGYPVIAEDSGLEIDALQGELGIYSARFGGNVGYKEKISLVLEKMKDTPWEDRKARFICKAVFYDMKEDVKIITGGKVEGYIAYEPKGEKGFGYDPIFYFPLLDKTFGEIDKSEKNKYSHRFLAFSKLKLFLDAYCKGGKI
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: GP1BA_HUMAN
Sequence: MPLLLLLLLLPSPLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDLYDYYPEEDTEGDKVRATRTVVKFPTKAHTTPWGLFYSWSTASLDSQMPSSLHPTQESTKEQTTFPPRWTPNFTLHMESITFSKTPKSTTEPTPSPTTSEPVPEPAPNMTTLEPTPSPTTPEPTSEPAPSPTTPEPTSEPAPSPTTPEPTSEPAPSPTTPEPTPIPTIATSPTILVSATSLITPKSTFLTTTKPVSLLESTKKTIPELDQPPKLRGVLQGHLESSRNDPFLHPDFCCLLPLGFYVLGLFWLLFASVVLILLLSWVGHVKPQALDSGQGAALTTATQTTHLELQRGRQVTVPRAWLLFLRGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLSTVSIRYSGHSL
What is the function of this protein?
GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.
What are the official names of this protein?
Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HIS8_RUBXD
Sequence: MRFRAELEPLSPYNPPRASQEAAAERGTGGLVKLTSNELSFGPLPEAEAALAEALPRANRYPDRYAAALREAVAAANPGSDVANVLVGNGSSEVLQNLLMLVERPGEVLFPWPTFTLYPSIAGTLGLRARRVPLTEEHRVKPEALLSAVTGETRAVILCNPNNPTGTHLTLEEVSALADALPEDVLLILDEAYQEFVADPAYHGSHALALERPNVAVARTFSKAHGLAGFRVGYGLASREIADYAERVRFPFSVNLAAQVAATASMQAREKIRARAEFVIRERERVERAFREAGLNYVHSQGNFVLVETSPALFERAGVLVREGDPLGYPGWSRVTIGNTQENDLVIGALG
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ATP8_CERSI
Sequence: MPQLDTSTWSITIVSMIITLFIMFQLKLSKYSYPSSPELKLTKTPTHTTPWESKWTKTYLPLSLPQQS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: VG71_BPML5
Sequence: MSGKIQHKAVVPAPSRIPLTLSEIEDLRRKGFNQTEIAELYGVTRQAVSWHKKTYGGRLTTRQIVQQNWPWDTRKPHDKSKAFQRLRDHGEYMRVGSFRTMSEDKKKRLLSWWKMLRDDDLVLEFDPSIEPYEGMAGGGFRYVPRGIEDDDLLIRVNEHTNLTAEGELLWSWPDDIEELLSEP
What is the function of this protein?
Confers immunity to L5 superinfection, required for maintenance of the lysogenic state.  Binds to multiple asymmetric DNA sites.  Regulates transcription initiation at an early lytic promoter, Pleft, but also affects downstream gene expression at 'stoperator' sites in the phage genome.
What are the official names of this protein?
Repressor-like immunity protein, Gp71.
Protein: Y260_TREPA
Sequence: MCYYRYVQVHSIWRRFCALGLLVPFLLLLFSCTNTVGYGVLQWSLPDLGLSTGDILPVYVRSNVSQVYIVEIQKKKVELPFWQLKLCRTKKEALQYAERLREYRYSYATSVLDGLPLREGPENTAPQVYRLREGQAVKLLWKGTGKAVYRGENRLEGDWFKVMTEDGTTGWCFSHGLSLFDERESRPTVRETDDLARDRDLQHVLNSAWYPEYYRTMVEQRRIDLEKMASGWGLFVGEKKGLARIELPDAHYAFPYSRLVKTGSNGYLFDGSSLSIYVRDAHTLAAQFTDEAGRLRIERFVTLEKTPEEIIAEEQLRRSALLEHVCTPGLRLHSEIYGTLSFTERNVFTWTGARALSPALIPAGAGSTGRVALRCFIDQSLKSEYEGVLSFDFDSAQEWVHFLYLRTPGGLKLEHIDSTHLKDATVLRRSVSPVVLYFAPEGHAEPQP
What are the official names of this protein?
Uncharacterized protein TP_0260.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KATG2_BURCJ
Sequence: MSNEGQCPFNHANGGGTTNRDWWPNELRLDLLSQHSSKTDPLDPGFNYAEAFNSLDLDALRKDLAALMTDSQDWWPADFGHYGPLFVRMAWHSAGTYRMGDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLLILTGDVALTTMGFKTFGYAGGREDTWEPDRDVYWGSETTWLGGDLRYDKGGACESQHGGNAGRNLENPLAAVQMGLIYVNPEGPDGNPDPVAAAYDIREVFGRMAMNDEETVALIAGGHAFGKTHGAGPADNVGLEPEAAGLEQQGLGWKNSFGTGKGADTITSGLEVTWSDTPTQWGMGFFKNLFGYEWELTKSPAGAHQWVAKNAEPTIPHAHDPSKKLLPTMLTTDLSLRFDPVYEKISRHFMDNPDVFADAFARAWFKLTHRDMGPRARYLGPDVPTEELIWQDPIPAVDHVLVDDTDVAPLKETILASGLSVAELVSTAWASASTFRGSDKRGGANGARIRLAPQKDWAVNEPARLAKVLKVLERIQGEFNSTQPGGKKISLADLIVLAGGAGIEQAAKRAGHDVVVPFAPGRMDASQEQTDAHSFAVLEPVADGFRNFVKGKFAVPAEALLIDKAQLLTLTAPQMTALVGGLRVLNVQTGDEKHGVFTDQPETLTVDFFRNLLDMATEWKPIAGEDTYEGRDRRTGELKWTGTRVDLVFGSNAVLRALSEVYASADGEAKFIRDFVAAWVKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.  Shows peroxidase specificity towards odianisidine, ABTS and pyrogallol, but methoxyphenol and 2-chloronaphthol are not peroxidized.
What are the official names of this protein?
Catalase-peroxidase 2, CP 2, Peroxidase/catalase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RS12_CHLL3
Sequence: MPTIQQLIRHGRSVKVSKTASPALEKCPQKRGVCTRVYTTTPKKPNSALRKVARVRLSNKIEVTAYIPGEGHNLQEHSIVLIRGGRVKDLPGVRYHIVRGTLDTSGVSDRKQSRSKYGAKQPKAVAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SIA4C_HUMAN
Sequence: MVSKSRWKLLAMLALVLVVMVWYSISREDRYIELFYFPIPEKKEPCLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITSSSIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITLKSMAGSGHNVSQEALAIKRMLEMGAIKNLTSF
What is the function of this protein?
A beta-galactoside alpha2-3 sialyltransferase involved in terminal sialylation of glycoproteins and glycolipids (PubMed:8288606, PubMed:8611500).  Catalyzes the transfer of sialic acid (N-acetyl-neuraminic acid; Neu5Ac) from the nucleotide sugar donor CMP-Neu5Ac onto acceptor Galbeta-(1->3)-GalNAc- and Galbeta-(1->4)-GlcNAc-terminated glycoconjugates through an alpha2-3 linkage (PubMed:8288606, PubMed:8611500).  Plays a major role in hemostasis.  Responsible for sialylation of plasma VWF/von Willebrand factor, preventing its recognition by asialoglycoprotein receptors (ASGPR) and subsequent clearance.  Regulates ASGPR-mediated clearance of platelets (By similarity).  Participates in the biosynthesis of the sialyl Lewis X epitopes, both on O- and N-glycans, which are recognized by SELE/E-selectin, SELP/P-selectin and SELL/L-selectin.  Essential for selectin-mediated rolling and adhesion of leukocytes during extravasation (PubMed:25498912).  Contributes to adhesion and transendothelial migration of neutrophils likely through terminal sialylation of CXCR2 (By similarity).  In glycosphingolipid biosynthesis, sialylates GM1 and GA1 gangliosides to form GD1a and GM1b, respectively (PubMed:8288606).  Metabolizes brain c-series ganglioside GT1c forming GQ1c (By similarity).  Synthesizes ganglioside LM1 (IV3Neu5Ac-nLc4Cer), a major structural component of peripheral nerve myelin (PubMed:8611500).
What are the official names of this protein?
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4, Alpha 2,3-ST 4, Beta-galactoside alpha-2,3-sialyltransferase 4, Alpha 2,3-sialyltransferase IV, Gal-NAc6S, Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase, Gal-beta-1,4-GlcNAc-alpha-2,3-sialyltransferase, N-acetyllactosaminide alpha-2,3-sialyltransferase, SAT-3, ST-4, ST3Gal IV, ST3GalIV, ST3GalA.2, STZ, Sialyltransferase 4C, SIAT4-C.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single- pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Protein: RR11_VITVI
Sequence: MAKPIPRIGSRRNGRIGSRKSARRIPKGVIHVQASFNNTIVTVTDVRGRVVSWSSAGTCGFRGTRRGTPFAAQTAAGNAIRTVVDQGMQRAEVMIKGPGLGRDAALRAIRRSGILLSFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PGMC_POPTN
Sequence: MVLFNVSRVETTPFGDQKPGTSGLRKKVKVFKQPNYLQNFVQSTFNALTPQNVRGATLVVSGDGRYFSKDAIQIITKMAAGNGLRRVWVGQNGLLSTPAVSAVIRERVGVDGSKATGAFILTASHNPGGPNEDFGIKYNMENGGPAPEGITDKIYENTKTIKEYLTADLPDVDITTIGVTSFSGSEGQFDVEVFDSASDYIKLMKSIFDFESIRKLLSSPKFTFCYDALHGVAGAYAKRIFVEELGAQESSLLNCVPKEDFGGGHPDPNLTYAKELVARMGLGKSNSEVEPPEFGAAADGDADRNMVLGKRFFVTPSDSVAIIAANAVEAIPYFSAGLKGVARSMPTSAALDVVAKSLNLKFFEVPTGWKFFGNLMDAGLCSVCGEESFGTGSDHIREKDGIWAVLAWLSILAYKNRENLGGGKLVTVEDIVHNHWATYGRHYYTRYDYENVDAGAAKELMACLVKLQSSLTEVNEIVSGIQSDVSKVVHADEFEYKDPVDGSISKHQGIRYLFEDGSRLVFRLSGTGSEGATIRLYIEQYEKDPSKTGRDSQDALAPLVAVALGLXKMQEFTGRSAPTVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase, cytoplasmic, PGM, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_GRABC
Sequence: MGPVPEEHQRESETVASNGANESGAAVTGIPQREAKHVSGTAVSGLAKRYASALYSYAGDSGDLDGVIARIEALGRLIDESADLRSLLGSPLVDVNRARDAVLAVLDRQGFTRIERNFVGTVANNRRLGSLRSIISAFAVLVAEKRGEAVAVVESAHELTEVQEHQLRASLIEAGYGNVRIEKHVDPSLLGGLVVRIGTRLYDTSLKSRLQRLQYAMKGAA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: URED_JANSC
Sequence: MLDAATPTHQRVRGRAMARFTGRRLRDLHQSGSAKVLIPRVFGRAPEVVFLNTAGGITGGDRLDYALHVDDGTCVGTTQTAERAYRSHGPMGRVSTRLTIGQGATLHWVPQEMILFDGVALERDLSVEMAGDAELVMLETLVLGRAAMGEVLRDLHLRDRRRVTRGGKLAMVEAIGLGPDDFASSSPAGLNGAVATASLTLMAQDAEDRLNALRAVLPTDVRSAASAWDGRLTARFLAPQAYPLRRAVARAVEQVTCGALPRVWQI
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_RHOP5
Sequence: MSEIGERVKKIVVEHLGVEPEKVVDAASFIDDLGADSLDTVELVMAFEEEFGCEIPDDAAETILTVGDAVKFLEKNAKS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_DINSH
Sequence: MAQISLTFPDGNARDFDAGVTPAEVAASISTSLGKKAISATVNGAHHDLQWPIDADASIAIHTLKDDAQALELIRHDCAHIMARAVQEIWPDVKVTIGPVIENGFYYDFDRAEPFTPEDLGAIEAKMKEIINARDPVRTEVWDRPRAIAHYEANGEPYKVELIEAIPGNEPLRMYWHGDWQDLCRGPHLQHTGQVPADSFKLMSVAGAYWRGDSSRPMLQRIYGVAFQNRDALKKHLHMLEEAAKRDHRKLGREMNLFHMQEEAPGQVFWHPNGWTVYTTLQDYMRRRQRENGYVEVNTPQVVDRKLWEASGHWDKYQENMFIVEVDEEHAREKAINALKPMNCPCHVQVYNQGLKSYRDLPLRMAEFGACNRYEPSGALHGLMRVRGFTQDDAHIFCTEDQIQDETARFIRMLSTIYRDLGFESFDIKFSTRPEVRAGSDAVWDKAEAALEAAIRTVTDDFELDPGEGAFYGPKLDFKLTDAIGREWQLGTFQADFVLPERLDATYIGEDGAKHRPVMLHRAILGSFERFLGILIENFAGKLPFWLAPRQVVVASIISEADDYVREVVAALTRAGIRAEADIRNEKINYKVREHSVGKVPVILAVGRREMEERTVTLRRLGEKQTSVVGLDALVADLAAEATPPDQRPDQPAV
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALL3_HUMJA
Sequence: MDNPFENGMKACTSLYDKYYQNCVMKLPPGACIDSENYRKCLTNHIGSCDIDTCFEDVSIACRSIYPSNYAECATTHHNICGDLQG
What are the official names of this protein?
Allergen Hum j 3.
Protein: CA1A_CONER
Sequence: MFTVFLLVVLATTVGSFTLDRASDGRDAAANDKASDLIALTARRDPCCYHPTCNMSNPQICG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  Probable competitive antagonist of fish muscle acetylcholine receptor (PubMed:32245200).  Inhibits postsynaptic nicotinic acetylcholine receptors (nAChRs) from zebrafish (IC(50)=58-100 nM) (PubMed:32245200).  Blocks mammalian nAChR composed of alpha-1/gamma and alpha-1/delta subunits.  Blocks central nervous system nAChR composed of alpha-4-beta-2/CHRNA4-CHRNB2 subunits and peripheral nervous system nAChR composed of alpha-3-beta-4/CHRNA3-CHRNB4 subunits.  Low toxin concentrations potentiate currents in muscle nAChR composed of alpha-1-beta-1-gamma-delta (CHRNA1-CHRNB1-CHRNG-CHRND) subunits and central nervous system nAChR composed of alpha-4-beta-2/CHRNA4-CHRNB2 subunits, but not peripheral nervous system nAChR composed of alpha-3-beta-4 subunits.  Also exhibits inhibition of D. melanogaster alpha-7/CHRNA7 nAChRs (PubMed:25466886).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (lacks the Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin EI.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_CAMC1
Sequence: MQRTLSIIKPDAVKKNVVGKIIDRFESNGLRIAAAKKIKLSKCDAKAFYAVHKDRPFFNDLVDFMVSGPVVVMVLEGENAVAKNRELMGATNPKEAAPGTIRADFADSIDANAVHGSDSLENAVNEINFFFASREIC
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y807_DECAR
Sequence: MMKGGLAGLMKQAQAMQENMKKAQEQLAQVEVEGVAGAGMVKVLMTCAHEVRRVNIDPSVMDDREMLEDLIAAALNDAVRRGEALSKDKMSGFTSGLNLPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Daro_0807.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GPPA_SALTI
Sequence: MNSTSLYAAIDLGSNSFHMLVVREAAGSIQTLTRIKRKVRLAAGLNNDNHLSAEAMERGWQCLRLFAERLQDIPQPQIRVVATATLRLAVNAGEFIAKAQTILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFSDRNLAQENFDDAEKAARDVLRPVADELRFHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFTELNIQSMTLAGGALREGLVYGMLHLAVDQDIRSRTLRNIQRRFIVDTDQANRVAKLADNFLKQVENAWHIEPISRELLLSACQLHEIGLSVDFKQAPYHAAYLVRHLDLPGYTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAILFAGRRRDDLVPEITLQALNENLTLTLPGDWLAHHPLGKELIDQESQWQSYVHWPLDVR
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: TYSY_MYCS5
Sequence: MKQYLHLLEHIKTSGTFKKDRTNIGTISLFGLQARYNLKEGFPLLTTKKMAWKAICHELLWFLKGDTNIKYLVDNNVNIWNEWPYEIFKKSNDYQGESLKEFSQKIKEDSSFAQKYGELGPVYGKQWRDFFGVDQISQVINDIKNNPTSRRLIVSAWNVAQIDKMALPPCHAFFQFYVNDNNELSLHLYQRSGDMFLGVPFNIASYSLLLSMVAQVTNLKVGEFIHTIGDAHIYSNHIDQVNTQLERAPYKLPKLILNKNIKNIFDFTFEDIELENYISHETIKAKVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.