PharMolix/UniProtQA huggingface dataset:
Protein: RL7_MESH2
Sequence: MAKITKEQFIESLKEMTIKEVMEFVDALKEEFGVDPSAVAVAATPVATEEVKTEVKLTLKAAGQQKVAVIKVVKDLLGLSLMDAKKLVDAAPSVLKEAIKPEEAEEYKAKLVAAGAEVSID
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: UL135_HCMVT
Sequence: MVWIWLGVGLLGGTGLASLVLAISLFTQRRGRKRSDETSSRGRLPAAASDKRGACACCYRNPKEDVVEPLDLELGLMRVATHPPTPQVPRCTSLYIGEDGLPIDKPEFPPARFEIPDVSTPGTPTSIDRSPSHCSSLSSLSSSTSVDTVLHQPPPSWKPPPPPGRKKRPPTPPVRAPTTRLSSHRPPTPIPAPRKNLSTPPTKKTPPPTKPKPVGWTPPVTPRPFPKTPTPQKPPRNPRLPRTVGLENLSKVGLSCPCPRPRTPTEPTTLPIVSVSELAPPPRWSDIEELLEQAVQSVMKDAESMQMT
What is the function of this protein?
Remodels the host actin cytoskeleton in order to impair immune recognition of infected cells.  Mechanistically, interacts with members of the host WAVE2 complex and redirects the complex to the plasma membrane.  In turn, the efficiency of immune synapse formation is greatly reduced.
What are the official names of this protein?
Protein UL135.
What is the protein family that this protein belongs to?
Belongs to the HCMV UL135 family.
What are the subcellular locations of this protein?
Host cell membrane. Host Golgi apparatus.
Protein: RL3_CARHZ
Sequence: MPKGILGRKVGMTQIFTEDGRAIPVTVIEAGPCVVVQKKTIANDGYNAIQLGFGEIKESKVNKPLKGHFNRANVKPMRYLREIRVENIDAYEVGQEIKVDIFTVGEKVDVTGISKGKGFAGGIKRHGFHRGPMAHGSKYHRRPGSLGAKGPARVFLGRKLPGRLGMERVTIQNLEVVKVDPERNLLVIKGSVPGIRGSLLIIKEAVKGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: LEPA_PROM5
Sequence: MTDISVSKIRNFCIIAHIDHGKSTLADRLLQDTGTVKQRDMQDQFLDSMDLERERGITIKLQAARMKYKAEDSQEYILNLIDTPGHVDFSYEVSRSLQACEGALLVVDASQGVEAQTLANVYLALENNLEIIPVLNKVDLPGADANKIKQEIEEVIGLDTSNAINCSAKTGEGIEDILEAVVSRIPHPQNEIKSPTRALIFDSYYDPYRGVIVYFRVISGSINKRDKILLMASKKHYELDEIGIMAPDEKQVDELHAGEVGYLAASIKSVADARVGDTITLFNSAAKEPLPGYKTANPMVFCGLFPTDADQYPDLRESLEKLQLSDAALKYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYDLDLIVTAPSVIYKINLNDKEQIFIDNPSTIPDPQSRESIEEPYVKMEIYSPNEFNGTLMGLCQERRGIFVDMKYITTDRVTLIYEIPLAEVVTDFFDQMKSRTQGYASMEYHLIGYRKNDLVRLDVLINSERADPLTSIVHKDKAYGIGRGLVEKLKELIPKQQFKIPIQASIGSRIIASESISALRKDVLSKCYGGDISRKKKLLKKQAKGKKRMKAMGKVDVPQEAFMAVLKLNQ
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: STAT3_PIG
Sequence: MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLSTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELNSECATSPM
What is the function of this protein?
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors.  Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene.  May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.  Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes.  Activated by IL31 through IL31RA (By similarity).  Acts as a regulator of inflammatory response by regulating differentiation of naive CD4(+) T-cells into T-helper Th17 or regulatory T-cells (Treg): deacetylation and oxidation of lysine residues by LOXL3, leads to disrupt STAT3 dimerization and inhibit its transcription activity (By similarity).  Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1 (By similarity).  Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation.  May play an apoptotic role by transctivating BIRC5 expression under LEP activation (By similarity).  Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity (By similarity).  Plays a crucial role in basal beta cell functions, such as regulation of insulin secretion.  Plays an important role in host defense in methicillin-resistant S. aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
What are the official names of this protein?
Signal transducer and activator of transcription 3.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3 (By similarity).
Protein: SPC24_GIBZE
Sequence: MLLSEEPATLIHHTIENFNIAPDKTAVARVTESLATLQQARDLRVREAESSLKKLSRQLATHTSRHDDLVTSHSSADHASNIARLDTLKFRTAKAAADAETDAERLALTAADLKARLRELELQGVEGDAAANARRRDPVDDEVLLRLKVYRSLGIDIERDERDGEWSKAVIRNDRKGDVHVVNMDKKFSRFFYANYFWQTL
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein SPC24.
What is the protein family that this protein belongs to?
Belongs to the SPC24 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Associated with kinetochores.
Protein: ACTP_SALA4
Sequence: MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTEAMAVHPKGTAIMSPGGLVQDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPAYKDAAGALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATEREELKVSKITVLVLGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NFUA_HAES1
Sequence: MQITISEAAQAHFRRLLDQQEEGTNIRIFVVNPGSPNAECGVSYCPKNAVETTDHEIKYSEFSAFIDEVSFPFLEDAEIDYITEEMGSQLTLKAPNAKMRKVADDAPLIERVEYAIQTQINPQLAGHGGHITLIEITKDGKAILQFGGGCNGCSMVDVTLKDGIEKQLLAMFADELTGVKDVTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: MNTR_LISMC
Sequence: MPTPSMEDYIEKIYSLIETKGYARVSDIADELFVHPSSVTKMVQKLDKDEYLIYEKYRGLILTPKGTQMGKRLLERHALLESFLSIIGVDPSHIYHDVEGIEHHLSWNSIDRIGDVVQFFENHPDALKTLKAMETNKPETKE
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHT17_ORYSJ
Sequence: MAGDQMHVLSALDSAKTQWYHFTAIVIAGMGFFTDAYDLFCISLVTKLIGRVYYTADGASKPGSLPPNVSAAVNGVAFVGTLTGQLFFGWLGDRVGRKSVYGMTLLLMIICSVASGLSFGDTPTSVMATLCFFRFWLGFGIGGDYPLSATIMSEYANKRTRGAFIAAVFAMQGFGILAGGAVAIGITAIFRSRFPAPPFAADPAASTPPQADYVWRLILMFGALPAALTFYWRMRMPETARYTAIVAKNAERAAADMSKVLQVKITAEQAEMASPVDKPFTSKPFGLFSGEFARRHGFHLLGTTSTWLLLDIAYYSQNLFQKDIFSAIGWIPEAKTMSALDELYHIARAQTLIALCGTVPGYWFTVALIDVVGRFKIQAAGFFVMTAFMLALAVPYDHWTAAGNQIGFVVLYALTFFFANFGPNATTFIVPAEIYPARLRATCHGISAASGKVGAIVGSFGFLYLAQSPVPAKAAAHGYPPGIGVRNSLFALAGCSLLGFLLTFLVPEPKGKSLEEMSRENEVGQP
What is the function of this protein?
High-affinity transporter for external inorganic phosphate.
What are the official names of this protein?
Probable inorganic phosphate transporter 1-7, OsPT7, OsPht1;7, H(+)/Pi cotransporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1194_METTH
Sequence: MVIIHSPSYDLHNHEGHVENSGRTRAILRAIESSDLSPRFVEPGMAGIDDILMVHSSTHVEYLEVFAGRGGGWLDYDTYMTPESFSVARLSAGGAMLAAEEALRDGWSYSLGRPPGHHATYDRSMGFCIFNNIAIAIEHARRNLGVSRPLVLDFDVHHGNGTSSIFYRDRDVMYISIHQDPRTLFPGTGFIDETGSGEGEGFNLNIPMPRGSGNREYLWILGMILPAVLEGFRPDMIFVSAGFDAHRRDPLAEIMVDEEFFSWIGWFIHQTGLPCTAVLEGGYDPEALGRSNIAFMRGLDGEEYEPETAAPGGVSEIFSQLSDRFSAYFNF
What is the function of this protein?
Probable deacetylase.
What are the official names of this protein?
Probable deacetylase MTH_1194.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family.
Protein: S36A4_HUMAN
Sequence: MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHEQELLPVQKHYQLDDQEGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCLTSGLK
What is the function of this protein?
Uniporter that mediates the transport of neutral amino acids like L-tryptophan, proline and alanine (PubMed:21097500).  The transport activity is sodium ions-independent, electroneutral and therefore functions via facilitated diffusion (PubMed:21097500).
What are the official names of this protein?
Neutral amino acid uniporter 4, Solute carrier family 36 member 4.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSA73_DROVI
Sequence: MSRFDESVNIYSDGHLLQVEYAQEAVRKGSTVGLRTKECVVLGVEKRAIDSLQIERTSRKIKKIDQHMAMTFAGLTADARVLVSRAQVEAQSHRLNFDRPASVEYITRYLARLKQTYTQSVARRPFGVSCLIGGFDEDGRPRLFQTDPSGIYYEWSANTTGRLGQTVNEYLEKNTAAISRTPDAASAMKHVVRALFTATSLDPASIELAVLRYWQPIEMVKPETLEYLLGVIKQEAVEEALTKAP
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-7-1B, Testis-specific proteasome 28 kDa subunit 1B.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CH10_NEIMA
Sequence: MTIRPLHDRVVVKRLEAEEKTASGIVLPGAAAEKPDMGEVIAVGAGKIGKDGARRPLDVKVGDKIIFGKYSGQTVKADGEELLVMREEDIFGIVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_SALCH
Sequence: MMSKQLAAQVPAEPVVLGKMGSSYGIRGWLRVFSSTEDAESIFDYLPWFIQKAGQWQQVQLESWKHHNQDLIIKLKGVDDRDAANLLTNCEIVVDSSQLPALEEGDYYWKDLMGCQVVTAEGYDLGKVIDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLATRTIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_NEIMB
Sequence: MQFSYSWLKTQADTELSSDKLEHLLTMSGLEVEEAETAAPAFAGVVIAEVKSVEKHPDADRLNVTRVDAGTGGLVQIVCGAPNVKAGIKVPCSLPGAVLPGNFKIKPTKMRGEVSDGMLCSTDELGLPDDGVNGLHILPEDAPVGTNIREYLDLDDTLFTLKITPNRADCLSIKGIAREVSALTGCAFRQPEIHTAPITGSRKQPVQINAPADCGRFISRVIENVNARATTPDWMKQRLERSGIRSISALVDIGNYVMLEIGQPMHVFDADKLSGSLHIRRAREGETLECLNEKTVSLSENTLVVADEKGVLSLAGLMGGAASAVSDGTQNIVLEAAWFAPEIIAGKSRQYGFGSDSSFRFERGVDYRLQADAIERATELVLQICGGAAGEMVEAQGELPEAKQVGLRLDRLKTVLGVDIPAEQVETILQHLGLQPEKTAEGFRVTAPSFRFDIEIEADLIEEIGRVYGYENIPDDYTSGRLKMLELPETRRPRFAVYNEMAARGYREVVSYAFVDEQWEQDFAANADPIRLQNPLAAQYAVMRSTLIGGLVEILQNNLNRKQNRVCVFEIARVFSKGSDGQFVQNERIGGLWYGAVMPEQWGGKTRNADFYDIKADVENLLKNKAVEFVKTGHPALHPGRAANIVSDGKVIGFVGELHPKWLQKYDLPQAPLVFEIDMAAVLECGKTRYRVVSKFQPVRRDLAFVMPEAMSHDDLLLVLKGAANKLVQEISVFDVYRGTGLPEGMKSVAVKVILQDMENTLTDEAVEPLIGKLIGAATAAGARLRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPGC_AMYOR
Sequence: MTTDSPTLSLSPGLDHRALAKAAQRVDELLDGLPSPSARTPAQREAASSALDEIRAARTEYVEAHAEEIYDRLTDGRTRYLRLDELVRAAASAYPGLVPTEAQMAAERSRRQAEKEGREIDQGIFLRGILSAPKAGPHLLDAMLRPTARALELLPEFVETGVVRMEAASLERRDGVAYLTLCRDDCLNAEDAQQVDDMETAVDLALLDPAVRVGMLRGGVMSHPRYAGRRVFCAGINLKKLSSGDIPLVDFLLRRELGYIHKIVRGVATDGSWRARVIDKPWLAAVDSFAIGGGAQLLLVFDHVVAASDAYFSLPAATEGIIPGAANYRLSRFTGPRLARQVILGGRRITADEPDARLLVDQVVPPEEMDAAIESALAALDGDAVRANRRMVNLAEEPPDGFRRYMAEFALQQALRIYGADVIGKVGGFAAGSR
What is the function of this protein?
Involved in the biosynthesis of the nonproteinogenic amino acid monomer (S)-3,5-dihydroxyphenylglycine (Dpg) responsible of the production of vancomycin and teicoplanin antibiotics.  Catalyzes the unusual conversion 3,5-dihydroxyphenylacetyl-CoA (DPA-CoA) to 3,5-dihydroxyphenylglyoxylate.  DpgC performed a net four-electron oxidation of the benzylic carbon of DPA-CoA and the hydrolysis of the thioester bond to generate free CoA.  It can also use phenylacetyl-CoA (PA-CoA) as substrate.
What are the official names of this protein?
(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: EFGM_TALMQ
Sequence: MVRPAQVRAFSGLARSATSTRLIPSQCQNALRCASLPGSRLSALPLRATQITSSPLRKWHQIRNASAAATATLAEQAAADPEGLSQEEIISNIDAEEWKRISKVRNIGIAAHIDSGKTTATERVLFYTGRINSIHEVRGRDSVGAKMDSMDLEREKGITIQSAATFCDWVKKEDGKEEKYHFNLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMKRYNVPRISFVNKMDRMGANPFKAIDQINSKLRLPAAAVQVPIGAEDEFQGVVDLIRMKAIYNEGPRGEVIVEKDEIPEHLKPVAEERRRILIETLADVDDEIAEIFLDEREPTNEQIKDAIRRATIALKFTPVFMGSALADKSIQPMLDGVCDYLPNPSEVTNLALDQKRKEAQVKLLPYGSEPFVGLAFKLEESNFGQLTYIRVYQGTLRKGANVFNARNDKKVKVPRIVRMHSNEMEEVQEIGAGEICAVFGVDCASGDTFTDGQLAYTMSSMFVPEPVISLSIKPKNNKDSANFSKAMARFQREDPTFRVSYDAESEQTIISGMGELHLDIYVERMRREYKVDCETGQPQVAYRETIGRRVEFDHLLKKQSGGPGDYARVVGWMEPSDSLEENKFEEQIVGGAISEKFLFACEKGFNLATEKGPLIGHKVLGTKMVINDGATHMTDSSEMSFKNATQQAFRKAFMESQPHVLEPLMKTVVTAPIEFQGDVIGLLNKRNATINDSEIGVDEFTVYADCSLNGMFGFSSHLRAATQGKGEYTMEFSHYEKAPGQLQKELVQKYLKAQADRHKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NDHO_SYNS3
Sequence: MAEPSADPTPTAKPAATLKKGALVRVNRTSYLGSVEASASDPRPPEYIFEGPGELLLVKGEYGQVRWRRPVPDVWLKLSQLEVFS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EX7L_THIDA
Sequence: MDWSEDPGMPPPAPPVLSVSELNRMARRALESQLPLLWVEGEVSNFMRAASGHWYFSLKDATAQVRCVMFRGRNQFAEFTPANGDHVEIRALPSLYEARGEFQLGAESIRRAGAGRLYEAFVRLKAKLEGEGLFDPAKKRALPRFPRCLGVVTSPQAAALRDVLTALGRRMPGLPVILYPTPVQGSGAGAQIAAAIRAAGTRAECDVLLVCRGGGALEDLWAFNDEAVARAIAASPIPVVSGVGHETDFTLADFAADLRAPTPTAAAELASPVAEEMLRALERHARLLRQHHARRQQADMQRLDYLARRLIHPAQQLRRRQLGIAQLAQRLHGAVRARLTREQLRIAQLGERRTSPRHALQRQQQVLESLGARAARAAESARIGRGLTLARLASSLAHLNPDNVLARGYSIVQQENGAVVHDAATLRAGDGLEIRFHRGAAHARVESAQPE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C562_CERS4
Sequence: MTQEPGYTRLQITLHWAIAGLVLFNYIFGETMERAYDAVRQNVEPAGVGHYLHVVVGLAVLVLTLVRIGARFVLGVPEKGTTPGDKVAAGLQGLLYLLTLLVPALGMTAWGGGQAWAAGPHVLAANAIMLLALVHAVSALFHQYVLKDRLLLRMMRPR
What is the function of this protein?
Cytochrome b562 is an integral component of the cytochrome b-c1 complex in the cyclic electron transfer system of photosynthetic bacteria.
What are the official names of this protein?
Cytochrome b562, Cytochrome b-562.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b561 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATX2_DROME
Sequence: MNNNSKRKTRPTGGGASGGISRYNSNDNSLRPTNNKAGAGGGNGGAAVRPSAQGVYNNTFFMHSATALVGSVVEVRLRSGNIYEGVFRTFSGNFDIALELPACIKSKNLPEEGKVPKHIIFPADTVVTIVAKDFDSQYATAGAFQTDGAISDKCNGARPDEKELEPWDSGANGDIDIELDSAANGWDPNEMFRKNENTFGVTSTFDDSLASYTVPLDKGDSLEFKEAEAKAEKLAAEIENNPTCRDRLDLENGDEEALFAAVERPSTEQDQRGDRGDRERNDRDREREERDRDRDRDRGNKPRGAGDFQLRETMSSDRYITKQTRSITGPQLSHVGMSSQGSGRDRDTRGDGSMMMQSGGGSGQGGSTQSTAALMLAGGLKGVGPAPSANASADSSSKYSGGSMVKRKTVPQGGKVMRNNVPTGGSNVSVSQGGNGNSVGQNKGGYQPSMGMPSQYSYQGNSQIMHGSSQYRNQSHMGGANKLNGDSNANTNKPLPQRQMRQYQGSQSNSSLNYGGEPQSLGKPVHGSHGGHPGQNSNSPPLQTAGPQQQQQQQQQQQQQQQQQQPPQQQQHQNIQPQGQNTQPARQVRTRDNQMQELRQFGQDFQLAPSNTSPPQQQQQQQQQQQQHQVQQQQQRALQQSASPPQQQQQQQQQQQHVVLHQVPQTHLHQAALSQPHYVPQQQPQQAPLPQQQHVPHHMQQKAQQQQLVETQHQHVQKQHQSQPQVQQPPPQLLQDPSQQPLPIYHTMPPPQTSPVVVTSPVLLEQPPPQPMPVVQQQQTQQLATPKPEVSPAPPSSNTTTPTGIASTPTAGVIASAGSEKTTPAAPTPTSNSATVPTGTAATAGGATGTTPVVKKHVLNPSAKPFTPRGPSTPNPSRPHTPQTPVPMTNIYTTTGGHVPPAANQPIYVMQPQHPFPPQTHPQAGQPPRLRRSNYPPMAASQMHVSASAATGQPLITAGPIPQFIQYGHAPHQQQFQSHTYAPMQMRVYPDQPQQLQFMTQTPQSTTPSPGQPHQQFHPPPQPSPAGGGPQPAFTPPTQAATYQLMCVHPQSLLANHYFPPPTPQHPQQNQQQYQIVMQQHQPQ
What is the function of this protein?
RNA binding protein that regulates various processes including circadian behaviors, actin filament formation, eye development and oocyte formation (PubMed:12524342, PubMed:28388438).  Forms a complex with tyf and pAbp which functions in adult circadian pacemaker neurons to sustain circadian rhythms likely by switching between activator and repressor modes of post-transcriptional regulation via interaction with Lsm12a or me31B (PubMed:28388438).  Forms an activator complex (Atx2-tyf activator complex) via association with Lsm12a and activates the TYF-dependent translation of per to maintain 24 hour periodicity in circadian locomotor behaviors (PubMed:28388438).  Forms a repressor complex (Atx2-Not1 repressor complex) via the me31B-dependent association with Not1 to promote Not1-dependent post-transcriptional gene silencing and support high-amplitude circadian rhythms in a per-independent manner (PubMed:28388438).  Regulates actin filament formation, though it does not directly assemble with actin filaments (PubMed:12524342).  Required for oocyte specification and oocyte positioning in the female germline (PubMed:12524342).  Also required for normal eye development and bristle morphology (PubMed:12524342).
What are the official names of this protein?
Ataxin-2 homolog, Datx2.
What is the protein family that this protein belongs to?
Belongs to the ataxin-2 family.
What are the subcellular locations of this protein?
Cytoplasm.