PharMolix/UniProtQA huggingface dataset:
Protein: TUP1_KLULA
Sequence: MSSVAASQNKINDLLEAIRQEFANVSQEANSYRLQNQKDYDFKINQQLAEMQQVRNTVYELELTHRKMKDAYEEEISRLKLELEQKDRQLASIAHGSTVGNVPGQVPQLSRNSGAQGNANIAPPNIPQPMVSQTVGTGMAPQMAPLNTQHPTQQTKSNAGEQAAANLAPVIQQQQQPQQQLPPQQQQQQQQQQQSNIPVTTAAPVQPAGGNLDQTVPNSISPQQQPTEQQQPASTATTAPATASTAPPTSAPSDQVGQDHYLVPADQRAVHAKPIPPFLLDLDSQLVPSHLKKQNNDYYVLHNPALPTDLDVELHKSLEHSSVVCCVRFSSDGEFLATGCNKTTQVYKVSTGELVARLSDDSASQPQPQPQNQTVTAETSTSNSNGSSAEDGTGNQNSAASTASSDLYIRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSGDRTVRIWDLTTGTCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSGSKDRGVLFWDTKSGNPLLMLQGHRNSVISVTVANGHPLGPEYGVFATGSGDCKARIWKYSKKNSQQNSTQIKEIKE
What is the function of this protein?
Represses transcription by RNA polymerase II.
What are the official names of this protein?
General transcriptional corepressor TUP1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TUP1 family.
Protein: EX7S_BARQU
Sequence: MKQEIQTGDITALSFEQALKQLEVIVENLERGDVPLEQSIDIYERGEALRKHCDRLLKAAEAKVEKIQLSEEGSPKGVEPLDSK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANG2_PANTR
Sequence: MDLPIEDSHDSSTSPKGKQPTTAEKSATKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQKNNWLKNSNGVTQGCLVNPTGNLPMWSNQTWNNSIWSNETQNIQSWSNHSWNTQTWCTQSWNNQAWNSPFYNCGEESLQSCMQFQPNSPASDLEAALEAAGEGLNVIQQTARYFSTPQTMDLFLNYSTNMQPEDV
What is the function of this protein?
Probable transcriptional regulator.
What are the official names of this protein?
Putative homeobox protein NANOG2.
What is the protein family that this protein belongs to?
Belongs to the Nanog homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IMT1_SCHPO
Sequence: MGRKCRKLLLKGIPICGVILLILWGYSLYNTLRFMVPGKATEPFTLSLSDVSDDTSAPGEMEKIPRVIHQLWKDENIPERWSNTVNSCRRQHPDENGWQFILWTDEKIMSFMNENYSWFMPVFHSYPYNIQKFDAARYFILYHYGGVYMDLDIGCKKPMDPLLSKATFILPSTEPIGYSNDWFAATPKHPFLYQAIHNLSKFNHRYFTKYPTVFLSAGPLFLSYQFCKYLLTPHEPVRVLPALLYGNGPNSFFSHVTGDSWHGTDAKVFIWIDRNSKSVLFFAFLAAFAILFLCLRVVFKRRRKRGIAASHSQIQELYP
What is the function of this protein?
With imt2 and imt3, is required for the synthesis of mannosyl phosphorylinositol ceramide (MIPC).  Catalyzes the addition of mannosyl to phosphorylinositol ceramide (IPC).  MIPC is essential for cell morphology, cell-surface distribution of ergosterol, localization for plasma-membrane transporters, and lipid-raft-mediated endocytosis of plasma membrane proteins to the vacuole.
What are the official names of this protein?
Inositol phosphoceramide mannosyltransferase 1, IPC mannosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 32 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: MTX2_CAEEL
Sequence: MSSSGVITQLVTDALSMNAAQDWEDVSLFTPYLNDQALMYDFADCLAVQTFLRMTSLPFNVRQRPNVDFISPDGVVPLLKINKTLITGFNAIVDFVHKKGVTLTSHLSETQVADMRANISMIEHLLTTVEKFVLWNHDETYDKVTKLRYGSVYHWPLSSVLPFVKRRKILEELSDKDWDTKTMDEVGEQADKVFRALSAQLGSQKYLTGDLPTEADALLFGHMYTLITVR
What is the function of this protein?
Involved in transport of proteins into the mitochondrion.
What are the official names of this protein?
Metaxin-2 homolog, Mitochondrial outer membrane import complex protein 2.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: COAD_BARBK
Sequence: MTIAFYAGSFDPITNGHLDVLRGSLLLADKVVVAIGVQAQKQSLFSFEERVDLITQVGRDLLNVGPDRLQVISFNNLLIDTAREIGASFLVRGLRDGTDFDYEMQMAGMNGIMAPELQTVFLPASISGRVITSTLVHQIAAMGGDVTHFVPQNVAQALRLKFKF
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_STRSY
Sequence: MNKIISVWKKMNLIRKIGIGVVLGVLLGLIAPKITVIALFGSLFVGALKAIAPLLVLTLVAHALSQAPAGQKSNMRTVICLYLFGTFAAAFIAVGASYLFPIKLVLSTTTTTDITPPQGIAEVFQDLLLKVVDNPINALATANYIGVLTWAAVFGLAFRHASKTTKDLLQSTAEVISKVVGWIIGLAPFGIMGLVFDTIANNGLTALKDYGLLLLLLVGSMIFVALVVNPLIAFLVMKKNPYPLVFECLRVSGVTAFFTRSSAANIPVNMQLCKRLGVDPDTYSVSIPLGATINMAGAAITINILTMAAVHTLGISVDFSSALLLSVVASLSAAGASGVAGGSLLLIPVACSLFVVPYVV
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBFA_CHLPB
Sequence: MTIRTEKVASLLQKELSAIFEKELPRSGPLMTVVQVKVTTDLGIARVYVSIIGSEKERKTAIAHLQNETRYIRKLLSAKIRHQFRRIPELEFYEDRLYEKAERIDLLIKQALGTSK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_AERHH
Sequence: MLSKRIIPCLDVKDGVVVKGVQFRNHEVMGGIVELARRYASEGADELVFYDITASSDERVVDKSWVSRVAEVIDIPFCVAGGIKSVEDARQILEFGADKVSINSPALADPTLITRLAERFGVQCVVVGIDSYFDAQSGHYQVKQFTGDESRTRTTAWHTLDWVEEAQKRGAGEIVLNVMNQDGMRQGYDLEQLKLVRAVCKVPLIASGGAGAMEHFRDAFTLADVDGALAASVFHKGLIPIPELKRWLKTEGVAIRE
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOL_HBVA6
Sequence: MPLSYQHFRKLLLLDDETEAGPLEEELPRLADEDLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPIFNPEWQTPSFPKIHLHEDIINRCQQFVGPLTVNEKRRLKLIMPARFYPNSTKYLPLDKGIKPYYPDQVVNHYFQTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQELQHSQRHGDESFCSQPSGILSRSSVGPCIRSQFNKSRLGLQPHQGPLATSQPGRSGSIRPRALPSTRRCFGVEPSGSGHIDYSANSSSHCLHQSAVRKAAYSHLSTSKRQSSSGHAVEFHSFAPSSARSQSQGPVFSCWWLQFRNTQPCSQYCLSHLVNLLEDWGPCVEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGLTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLIGSSGLSRYVARLSSNSRIHNNQYGTLQNLHDSCSRQLYVSLMLLYKTYGWKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHRESLYTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGSWGTLPQDHIIQKIKHCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQAKQAFTFSPTYKAFLNQQYLNLYPVARQRSGLCQVFADATPTGWGLAIGHQRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCTANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLRLPYRPTTGRTSLYAVSPSVPSHLPVRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: COAX_ACET2
Sequence: MILVIDVGNTNTVFGVYDGKKLLNHWRMETSKGKTSDEYGMFIVSLLSYEKIDVGKIEAVVIASVVPPIMYSLEHAIRKYFKLEPMVVGPGIKTGINIKYENPREVGADRIINAVAALELYGGPLIIVDFGTATTFCAVSSKGEYLGGVICPGIKISAEALFQKTAKLPKIDLVKPETVIGRNTVSSMQSGIIYGYVGEVDYIVRRMKKEMKEDNIKVIATGGLARLIASESETIDEINGLLTLEGLRIIYERNK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAR1_ASHGO
Sequence: MSAKLSESDLNDFIGAQVACVKPTRTLHTADEGDEALEVGKEPQEATKVSISLQDCLACAGCITSSEEILLSRQSHGVFLEAWRSLAPKALAVSVAPQSRLSLAQHFGLSVAELDQCLSGVLGSYFGAKYVVGTQLGRELSVQQTNARLVERKQQGVQGPLLCSVCPGFVLYAEKTKPGLVPYMLDVKSPQQITGALLHAADPNIYHLSLMPCFDKKLEAAREDCAREVDCVLTPREFVALLDELQLDLHSFAGAAVPIAQLTPPGWDPRVSWCSSAGSSSGGYAYQYILHMQRLHPGSTIATQAGRNADLLEHRLLAPSGVLLASAGELYGFRNIQNLVRKLLSPATKRSAKVVRRRLPQASPAPPATDPCNADFIEVMACPSGCINGGGLLNGGLGPSQRRDLVSQLNEGYARLPTLDIPMPTYSQPSYIYNLRPLAPTDDVLTVANAW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: TRHO_BACC2
Sequence: MATTKPYRVLLYYMYTTIENPEEFAAEHLEFCNSLELKGRILVAKEGINGTCSGTVEQTEKYMEAMNNDPRFDGIVFKIDEEEGHAFKKMHVRPRPELVTLRLEDDINPHEITGKYLEPKDFYEAMKQEDTVIIDARNDYEFDLGHFKGAIKPDIESFRELPDWIRENKETLEGKKILTYCTGGIRCEKFSGWLVREGYEDVSQLHGGIVTYGKDPEVQGELWDGQCYVFDERIAVPVNQKEHVIVGKDHFTGEPCERYVNCSNPECNKKILCSEENEAKYLRACSHKCRVSPRNRYVIQHELTEEQVAAALEKIEAGK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RS10_COXBN
Sequence: MSDNQRIRIRLKAFDHRLIDRSTREIVETARRTGAIIRGPILLPTKIERYTVLISPNIDKDARDQYEIRTHKRLVDISEPTDKTVDALMKLDLAAGVDVQIELLNKKSGA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL15_CHLTR
Sequence: MIKLECLQDPSPRKRRTKLLGRGPSSGHGKTSGRGHKGDGSRSGYKRRFGYEGGGVPLYRRVPTRGFSHTRFDKCVEEITTQRLNEIFDNGAEVSLEALKERKVIHRETSRVKVILKGALDKKLVWKDAAIVLSEGVKSLIEAV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: CMOA_CAMLR
Sequence: MKDEIFKKPLEKQFEFDANVASVFDDMVARSVPFYAQNLKLITQLITHFAPQNAKICDLGCSTASLLLALFEKRKDLQLSGVDNAKAMLDIARNKTSAFGARVDFYEQNLDEFSFFKNDVFVATYTMQFIRPPKRQEIIDKIYQNLNDGGIFIMSEKILYEDVKISKKMIEIYENYKQDQGYSKLEIATKREALENILIPYTQNENINMLKNSGFKIIESVFKWVNFETFVAFK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: SNAPN_KLULA
Sequence: MDIDAEDATKSGLHPIELCVYSLLSGNLESIYQSINELRESQAVLILRLKQLRETCKDEQDRINKYCSLNAEIERLDKLETKVDVVLKRYEKMVGSISE
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit SNN1, BLOC-1 subunit SNN1, SNAPIN-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SNAPIN family.
What are the subcellular locations of this protein?
Endosome.
Protein: CHLL_PROMP
Sequence: MTSTINKPLDGEGSVQVKQDPKVNIEEGALVIAVYGKGGIGKSTTSSNLSAAFSKLGKKVLQIGCDPKHDSTFTLTHKMVPTVIDILEEVDFHSEELRPTDFMFEGFNGVMCVESGGPPAGTGCGGYVTGQTVKLLKEHHLLEDTDVVIFDVLGDVVCGGFAAPLQHANYCLIVTANDFDSIFAMNRIVSAIQAKAKNYKVRLGGVVANRSKDTDQIDKFNNRTGLKTMAHFKDVDAIRRSRLKKCTIFEMEPTEDVVEVQNEYLSLAKNMLDNVEPLEGTPLKDREIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: IF2_PROM2
Sequence: MTISDKIRIYELSRDLNLDNKDILGAAQKLSISVKSHSSSISAEEAEKIKNLINKKNPDKKILSIKKPSIKKDNYKQNKEDKSSLISSVEEKPFKDNPEKKPLLKKPLNKPESLKIISNQPKSLNKPTITNSSQSQANLTNQNLNSKTSQNLNQDKRNFRNNLTPPIKSPTKPPIQLIAKPKNTTKNVQSNESSQNILNSGGGRQISNKPDQNSSKSKTKNINNRMSPPELVGAPIRREGPNKQNNKQKTSFKQTVPNRPGMLNRPGLRNKPSDQGRPGSFNRQTNTNRPGAPSSNKPGMPNRPGLRNKPSDQGRPGSFNRQVNTNRSGAPIRPGMPNRPGSKFNGPKSPGMRKPVSPNELLKLQKTNKSENDKQVINNNEKQNSETTKQKVKAPNSRPHTAPNSKKLPHRTFSNNSKKPGKTDWDDSAKLEALRNKNPQKQRQKVRIIGENDDSLTSETSGYSGEKFSILSASLARPKKEKSDESKSQKTIKQFKKKKKETTRQRQKRRAMELKAAKEAKQIRPEMIIVPEDNLTVQELADKLSLESSEIIKSLFFKGITATVTQSLDLATIETVAEEFGVPVLQDDIQEAAEKTVDMIESEDLDNLIKRPPVITVMGHVDHGKTSLLDSIRESRVASGEAGGITQHIGAYQVEFEHESKKKKLTFLDTPGHEAFTAMRARGTKVTDVAVLVVAADDGCRPQTLEAISHARAAKVPIVVAINKIDKEGASPDRVKQELSEKNLIAEDWGGDTVMVPVSAIKKQNINKLLEMILLVSEVEDLQANPDRFAKGTVIEAHLDKAKGPVATLLVQNGTLKSGDVLAAGSVLGKIRAMVDEHGNRIKDAGPSFPVEALGFSEVPTAGDEFEVYPDEKTARAIVGERATDARATKLAQQMASRRVSLSSLSTQANDGELKELNLILKADVQGSVEAILGSLEQLPKNEVQVRVLLSAPGEITETDIDLAAASGSVIIGFNTSLASGAKKAADANDVDVREYEVIYKLLEDIQLAMEGLLEPDLVEESLGKAEVRATFSVGKGAIAGCYIQTGKLQRNCSLRVIRSEKVIFEGNLDSLKRSKDDVKEVNTGFECGVGCDKFSSWIEGDIIEAFKFVTKKRTLTQE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_LACLM
Sequence: MTENITTETRPSIYGLTRDQLIEWAIENGEKKFRATQVWDWLYRKRVQSFEEMSNLSAVFIDKLNEAFILNPLEQVVVQESADGTVKYLFMLPDKVMIETVLMRQSYGLSVCVTTQVGCNMGCTFCASGILKKERDVTAGEIVSQIMLVQKYFDERGLDERVSHVVVMGIGEPFDNYEHLMNFLRVINDDNGLAIGARHITVSTCGFMPAKIKEFAHDNLQINLAISLHAPNNELRTSLMRITRNAPLEKLFEAIDYYTETTNRRVTYEYIMLSGENDSPEIAQQLADLIKSRNKLSYVNLIPYNPVAEHIKYERSTKDNTAKFYDVLKKNGINCVVRQEHGTDIDAACGQLRSKQIKKNKAKLA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMMP3_VIPAA
Sequence: MIQVLLVIICLAVFPYQVSSIILESGNINNYEVVYPQKVTALPKGAIQQLEQKYEDAMQYQFKVKGEPVVLHLEKNKDFFPEDYSETHYSPDDREITTNPPVEDHCYYYGHIQNDADSTASISACNGLKGYFTLRGVTYLIEPLKIPESEAHAIYKYENVEKEDEDPKKCEFRRAGTECRPARSECDVAEYCTGQSAECPTDVFHSNGKPCLNNFGYCYNGNCPIMYHQCYALFGPNATVGQDGCFEWNKKGESYFYCRKENDVPIPCAPEDIKCGRLFCELIKNTCKYDYSEDPDYGMVDHGTKCGDGKVCINRHCVDVTTAY
What is the function of this protein?
Abolishes platelet aggregation induced by collagen, ADP (IC(50)=292 nM) and arachidonic-acid.  The inhibition of collagen-induced platelet aggregation may be due to its ability to bind collagen and block the binding site on collagen for platelets and/or to its ability to bind to the platelet alpha-2/beta-1 collagen receptor (ITGA2/ITGB1) to block its interaction with collagen and hence prevent platelet stimulation.  The inhibition of ADP- or arachidonic-acid-induced platelet aggregation may be due to it acting as an antagonist of the ADP receptors or thromboxane-prostanoid receptors of the platelets, respectively.  Does not interact with integrins alpha-IIb (ITGA2B) or beta-3 (ITGB3) nor platelet glycoproteins VI (GP6) or IX (GP9) in vitro, however, the detection is dependent on experimental conditions and may happen in vivo.  Able to bind to platelet glycoprotein Ib alpha chain (GP1BA) receptor in vitro, although this interaction may have pathologically only limited effect in vivo as it is not able to abolish the von Willebrand factor (vWF)-dependent platelet agglutination induced by ristocetin.  Does not affect blood coagulation.
What are the official names of this protein?
Disintegrin-like/cysteine-rich protein MPIII-3, D'C protein MPIII-3, Metalloproteinase-like protein of class P-III MPIII-3, Snake venom metalloproteinase precursor-derived protein MPIII-3, SVMP precursor-derived protein MPIII-3, Snake venom metalloproteinase-like, SVMP-like, Vaa-MPIII-3, VaaMPIII-3.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIe sub-subfamily.
Protein: MNMG_NITOC
Sequence: MSVFYQYEVIVVGGGHAGTEAALAAARQGVRTLLLTHNIETLGQMSCNPAIGGIGKGHLVKEIDALGGLMAQAADQAGIHFRMLNARKGPAVRATRAQADRALYKAVVRKALEQQSCLSLFQQAVTDLVVKGERVVGVRTQLGLTFYAPAVVLTVGTFLGGRIHVGLTNHEGGRAGDPPANILSSRLRELPFRVARLKTGTPPRIDGRSIDYSQLEVQPGDDPVPVFSFLGSAEDHPQQVSCHITRTNLCTHEIIRASLDRSPIYSGEIEGIGPRYCPSIEDKVVRFSDKASHQIFIEPEGLETFEIYPNGISTSLPFDVQVALVRSIQGFEQAHITRPGYAIEYDFFDPRDLKPSLETSFLQGLYFAGQINGTTGYEEAAAQGLIAGLNAGLQVQEKEPWYPRRDEAYIGVLIDDLITCGTSEPYRMFTSRAEYRLLLREDNADLRLTPIGRELRVVDEVRWRRFNTKWKAIERENQRLVQQRIEPDKVSEGEAVTLLGEPLRREYRLIELLRRPHISYEKLMRLIGEPMAVEPAVAEQIAIQAKYAGYIERQQLEIARQQRHESLRLPLDLNYHQVRGLSVEVQEKLARVQPATLGQATRIPGVTPAAISLLLVYLKRARFLEETGV
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_OENBI
Sequence: MDVLSCSNNTLKGLYDISGVEVGQHFYWQIGGFQVHGQVLITSWVVIAILLGSASIAVRNPQTIPNDSQNFFEYILEFIRDVSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKLVELPHGELAAPTNDINTTVALALLTSVAYFYAGLSKKGLGYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NANT_ECOSM
Sequence: MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLACGFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKAPVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPTGVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROF4_RAT
Sequence: MSHLQNLLLDTLLGTKHVDGAALIKLQEKTLCVTSPGFSVMPCDVRTLLNGFAKNPLLTRREGLYFREKDYKCVRADDCSLYAKKENTGVVVVKTHMYLLVATYTAGMYPSVCVEATEKLGEYLRKKGN
What is the function of this protein?
Involved in male fertility.  Required for manchette development and acrosome biogenesis during spermiogenesis (By similarity).  Binds in vitro to phospholipids, including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA).  Contrary to other profilin family members, does not bind to actin in vitro (By similarity).
What are the official names of this protein?
Profilin-4, Profilin IV.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Localizes first in the acroplaxome and later in the manchette during spermatid head development. Localized mainly in the developing acrosome of haploid germ cells.