PharMolix/UniProtQA huggingface dataset:
Protein: MUKB_ECOBW
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQQENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTDEAPSQAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: MYRS_OCIBA
Sequence: MWSTISISMNVAILKKPLNFLHNSNNKASNPRCVSSTRRRPSCPLQLDVEPRRSGNYQPSAWDFNYIQSLNNNHSKEERHLERKAKLIEEVKMLLEQEMAAVQQLELIEDLKNLGLSYLFQDEIKIILNSIYNHHKCFHNNHEQCIHVNSDLYFVALGFRLFRQHGFKVSQEVFDCFKNEEGSDFSANLADDTKGLLQLYEASYLVTEDEDTLEMARQFSTKILQKKVEEKMIEKENLLSWTLHSLELPLHWRIQRLEAKWFLDAYASRPDMNPIIFELAKLEFNIAQALQQEELKDLSRWWNDTGIAEKLPFARDRIVESHYWAIGTLEPYQYRYQRSLIAKIIALTTVVDDVYDVYGTLDELQLFTDAIRRWDIESINQLPSYMQLCYLAIYNFVSELAYDIFRDKGFNSLPYLHKSWLDLVEAYFVEAKWFHDGYTPTLEEYLNNSKITIICPAIVSEIYFAFANSIDKTEVESIYKYHDILYLSGMLARLPDDLGTSSFEMKRGDVAKAIQCYMKEHNASEEEAREHIRFLMREAWKHMNTAAAADDCPFESDLVVGAASLGRVANFVYVEGDGFGVQHSKIHQQMAELLFYPYQ
What is the function of this protein?
Monoterpene synthase that catalyzes the formation of beta-myrcene from geranyl diphosphate.
What are the official names of this protein?
Beta-myrcene synthase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PMT4_SCHPO
Sequence: MASKSEKAVKKAQKLSKEPSVELTDTKSSDNVTPKQKSPNSTEEDVSLNLKTLKAKKFKLAFVLITVLSFITRFWNLNLPGEVVFDEVHFGKFASYYLQGKYFFDLHPPFAKLLLALVAKLAGYDGHYLFDNIGDNYKDNGVPYVTIRAWPALLSSLVPPVVFLIMKESGYDLLACIVSSSLVLFDNAHVTEGRLILLDATLLFSMVCAIYCYVRFFKLRHTPFSRPWWAWLFFTGFFLSCTISTKYVGFFTFLSIGLSVCLELWYLWDIKTGLTVERFFQHFLARFFCLIFFPFLFFLFWFYMHFNILTISGPGDSFMSLEFQETLSDNPITANSTILNYYDIVTIKHMGTNAFLHSHPEKYPIPYDDGRISSGGQQVTGYQFDDENNYWMILPADHYDPPIEAKLNVPVKNMDYIKLHHVGTNTDLMTHDVASPYHPTNEEFTTVSVDESAGKKHEYTLFQVVMSDNTDPQRPLYTKASSFKLIHKLTHVAMWSDPKPLPDWAFKQLEINGAKNIQTGSIFWTFDDIIGLKDSRLKKEKKIPKKLPFWKKYLELQLTMFRQNNMLTEFHPYSSNPSDWFTLHHGIAFWAKSEENKQIYLLGNPIGWWIIAGTVLSTTVVAAAEILLRQRGIRTLPETVRNHFYRSTMFFYMTYVFHYLPFFIMGRQLFLHHYLPAHLAGSLLVGAFIQLACRKSFRSPVSAGVPIPKDVDEKGHSKCHRKYGHVIELICTLLLIFVVIYCFTFFAPMTYGDKSLSVDEWTRRKWLDSWVFQYQKQN
What is the function of this protein?
Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.  Required for normal cell wall and septum formation.
What are the official names of this protein?
Dolichyl-phosphate-mannose--protein mannosyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AMYS_NEIME
Sequence: MLTPTQQVGLILQYLKTRILDIYTPEQRAGIEKSEDWRQFSRRMDTHFPKLMNELDSVYGNNEALLPMLEMLLAQAWQSYSQRSASLKNIDIERENNPDWILSNKQVGGVCYVDLFAGDLKGLKDKIHYFQELGLTYLHLMPLFKCPEGKSDGGYAVSSYRDVNPALGTIGDLREVIAALHEAGISAVVDFIFNHTSNEHEWAQRCAAGDPLFDNFYYIFPDRRMPDQYDRTLREIFPDQHPGGFSQLEDGRWVWTTFNSFQWDLNYSNPWVFRAMAGEMMFLANLGVDILRMDAVAFIWKQMGTSCENLPQAHALIRAFNAVMRIAAPAVFFKSEAIVHPDQVVQYIGQDECQIGYNPLQMALLWNTLATREVNLLHQALTYRHNLPEHTAWVNYVRSHDDIGWTFADEDAAYLGISGYDHRQFLNRFFVNRFDGSFARGVPFQYNPNTGDCRVSGTSAALAGLAQNDPHAVSRIKLLYSIALSTGGLPLIYLGDEVGTPNDDGWVQDSNKSDDSRWAHRPRYNEALYAQRNDPSTAAGQIYQGLRHMIAVRQSNPRFDGGRLVTFNTNNKHIIGYIRNNALLAFGNFSEYPQTVTAHTLQAMPFKAHDLIGGKTVSLNQDLTLQPYQVMWLEIA
What is the function of this protein?
Catalyzes the synthesis of alpha-glucan from sucrose.  Catalyzes, in addition, sucrose hydrolysis, maltose and maltotriose synthesis by successive transfers of the glucosyl moiety of sucrose onto the released glucose, and finally turanose and trehalulose synthesis, these two sucrose isomers being obtained by glucosyl transfer onto fructose (By similarity).
What are the official names of this protein?
Amylosucrase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNFH_STUST
Sequence: MKISVVYAAPRQPLLFDCRVAEGSSVAEAIEHSGVLRYCPDIDLSKQKVGVYGKFVKLDSPLKEGDRVEIYQRITRVLDEDDDDDD
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: JDP2_DANRE
Sequence: MMPGQIPDPLVTAGSLPSVGPLAGFPATTLTEQLKLAELYRLGTVLSPLMLNRHAKRPFDAIKSEDDDDDERKKRRREKNKVAAARCRNRKKERTDFLQKESERLEMLNSDLKSQIEELKSERQQLIVMLNLHRPTCIVRTDSVKSDEHPLEPRED
What is the function of this protein?
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins.
What are the official names of this protein?
Jun dimerization protein 2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL35_SALPA
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SYFB_BORHD
Sequence: MPKVEVYRSILLGKIGKDLTDCELVSILEMAKAEICEFYTGNDKIKIEFNDTNRPDLWSYTGLARQIKTYLFGQLPSFEFFSTADNLQKFYGEILVSPEAFSIRPFIFGFLAKGMICNEQMLETLIQLQEKLCHNYGQKRKRVAMGMYSSASIEFPVSYVTCNSDYRFIPLGMDIEMSIKEINKRHPKGIEYASILEHFTEYPLLLDYNDKVLSYPPVINSHDIGALKVGDTDLFIEVTGTNLEATLLSLSVVACDLHDMGFEILPVKTVFPKETPFGKEIICPYYFQNTLEVSVESVNRMFGSNFTVNDMCLDLKKLGISAYFKELDKFYIIPPVYRNDFLHEVDVIEEIMIGRGLDSFKPELPKDFTLGKLSQIEEFSRKIKNLMIGMGFQEMIYNYLGSRTDFIEKMNIKSDEFLSVANPMTEGYEYVRGSIVPDLLKSESISSNFPYPHKIFEIGKVALKDLSSVDGTMTYDNLAFLMADKEFSFNEINSLVSSLFYYLNIEFKLRESSQTLYINGRGADILINDIILGSFGEVSPYILSNFGIMVPCCVLEINLNKILH
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_MYCTO
Sequence: MTSTRQAGEATEASVRWRAVLLAAVAACAACGLVYELALLTLAASLNGGGIVATSLIVAGYIAALGAGALLIKPLLAHAAIAFIAVEAVLGIIGGLSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLLQRGRVAGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNLAAAGVVSIFLLRHVVSGRQLVTALCALAAALGLIATLLVHSHDIETTGRQQLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGLQFCTRDEYRYTESLVYPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTTLRDVNAGSLDNPRVHVVIDDAMSWLRGAAVPPAGFDAVIVDLRDPDTPVLGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAGYAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAATVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDC2_MAIZE
Sequence: QNSIIFLINNGGYTIEVEIHDGPYNVIKNWNYTGLVEAFHNGEGACYTAKVRTEEELTEALEAALGPKKDCLCFIEVIVHKDDTSKELLEWGSRVSAANSRPPNPQ
What are the official names of this protein?
Pyruvate decarboxylase 2, PDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: DPOL_NPVOP
Sequence: MKILTYNQLQEAFRDYAPRDFAVSRDDAFRVMRIYYNEGGGNLVAFCNAQLGGRLAQFYFVMKMDLYSYKPCHNSHIFATCRNRCSSYNTFVAPGVKNVYMDKINVIKFKRNGSSFGEKTMALDKFLHNANRVHMQTPVIEGTYLRFRRAQRCRNNCVADDARPFALERFSDDFEVLDPSTLTTNIAPVMACYDIETHSDGHNSSKPECDVIMCIGLAVFKNDRFEKVCFVYHSEAVEIPQASDDTYVVVFNNENHMITAFFEFLKTVNPDVILDYNGDVFDLPYIRGRLKGDKPLLRRYDLPAMQPNTKLFITKIGNRTDTYYFNYYIHIDLYKYFGVDANKRDVENFQLNTLSQYYLGDAKVDLNWQTMVEMYNNKQLGTIIKYNVQDCLLPIRLFNKLKLTDFMYSQCIMYRLCTDDFICNISHLISSTFFHLALTNTRADPATGLTVSDPYFFNKDDLGLMSSKGSAGLTTGMSRLRRRRIPLKDVPATAIRLGAIDENVKYEGGKVLQPRAGVYEFAFSLDFNSLYLTIMIDICACLTNLILCEDGNVYLNQDKQAINVQLLLQLLKQRSELKKCRDSQTESEFLYDLYDQMQNLSKRTANSIYGYYGIFCKLLANHITRVGREKLTAAIGTVEGLSNDPDLLREFGLSTLTFKVLYGDTDSTFVLPVFRREEIPEEGRMATLGRICAAVEARVNGLFTNGYKMAFENLMSVLILLKKKKYCYINNNNKIVFKGWLVKKDMPVFMRVAFRAAIEQVLRHQDLSKCLDSLKANMLMYLDAFGITKPLTDYSFSMTYNDGAGKTAADDDEAAPPKRRVITVARHCREILVNKATDFVPGNGDRIPYVLLDMQGNVTQKAYPLRLFDAQTMRISWLKHMTILNTFMNELLEIFGDEHKDALAECYSAILEKYMQHQAYDKKRAALVKIATKRKAPSASDASGKRARKGAAPSDDESGSSEDEDAPCEPKCANNTFKFCLYKAQ
What is the function of this protein?
Replicates the viral genome, host DNA polymerases cannot substitute for the viral enzyme in this process.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: RL13_ARCFU
Sequence: MAVNVSRVIKTLGDDFTVIDASGHILGRLSSKIAKRLLNGERIVVVNAEKAVITGDKYMVFERYKEKYDRGSKEKGPYFPRHPERIFKRTVRGMLPWKSSRGRDAYRRLRVFMGVPEELQGREFEKIEDALLEKVSKTDKYVTLAEVSRYLGFRGV
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RK20_ORYSA
Sequence: MTRVPRGYIARRRRAKMRSFASNFRGAHLRLNRMITQQVRRAFVSSHRDRVRQKRDFRRLWISRINAATRIHKVFDNYSKLIHNLYKKELILNRKILAQVAVLNSNNLYTISNKIKIIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLR90_PLAVT
Sequence: MKSAAAFATFLTLSVFVATTEVQGTPGLRGLRSLADNQSTESSEGRKDHYNHHRHVKKVIKKVKKIAIPVPVAVPQYIPVPISGPSSVIASQNTAVVGSSNNVVAASGAGAVGSGVLGPGGVTPAPTTMTGRPVATPAPTTSVPSSLVNTDTSDNQLPTTPVAASQGGGIGSNLAGGSGNSVSMSGFGGGNQMGTFGNSMFGGRGANTGNGFNGNGNNSFGQQMGIDTPNGNMFGGFGRQGAAGGGGQRGFGGEAPDGINSVASGNALGGGITRRRRRL
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 90.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane.
Protein: YIDD_LACLA
Sequence: MKKVLVKAVHGYQRWISPALPPACRYYPTCSNYMVQAIEKHGPAKGLAMGTARILRCHPFCQPGYDLVPDHFSLRRNWAEPEKEEDSN
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RADA_METM7
Sequence: MADVLTELPGVGPSTAEKLIEAGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLCDLGFKSGVELLRQRQSVWRLSTGSKELDTVLAGGLESQSVTEFAGMYGSGKTQIMHQSCVNLQIAGKIYADLEGVVEEELEHPKAVYIDTEGTFRPERVVQMAEGLGIDGQLVLDNTFVARAYNSDMQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMATLNKLADLYNCIVLVTNQVAAKPDAFFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDSPHLPDSEAVFRITEKGIMD
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: RL21_BACCQ
Sequence: MYAIIETGGKQIKVEAGQEIYIEKLDVEAGETVTFDKVLFVGGENVKVGSPVVEGATVTAKVEKHGRAKKIIVFKYKAKKNNRKKQGHRQPYTKLVVEAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RTKN_RAT
Sequence: MQDRLRILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTGRRPSDSVQPPERSPCRGRVCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEQIQDTEMVLVDRTLTDISFQNNAIFAEAGPDFELRLELYGACVEEEGALAGAPKRLATKLSSSLGRSSGKRVRASLDSAGGSGNSPILLPTPAVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLTSHEENPAWLPLYGSMCCRLVAQPLCMTQPTASGTLRVQQAGELQSGTLVHGVLKGTNLFCYWRSEDADSGQEPLFTILINKETRVRAGELEQAPEWPFTLSISNRYGDDEVTNTLQVQSRDALQSWMEALWQLFLDMSQWKHCCDEVMKIETPAPRKPPQALAKQGSLYHEMAIEPLEDIAAVTDILAQREGTRLEPPPPWLAMFTDQPALRSSCSPASVPTWTQPLPWGRPRTFSLDAVPADHSLGPSRSVAPLPPQRSPQSRGFYSKSQLSTWLQSPV
What is the function of this protein?
Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis.  May play a novel role in the organization of septin structures (By similarity).
What are the official names of this protein?
Rhotekin.
Protein: POMP_BOVIN
Sequence: MNARGLGSQLKDSIPVTELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLPSSNLSLDILRGNDETIGFEDILNDPSQSELMGEPHLMVEYKLGLL
What is the function of this protein?
Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes.  Degraded after completion of proteasome maturation (By similarity).  Mediates the association of 20S preproteasome with the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Proteasome maturation protein, Proteassemblin.
What is the protein family that this protein belongs to?
Belongs to the POMP/UMP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Microsome membrane.
Protein: PGAP2_XENLA
Sequence: MVPISMAPDRGANSLVSLRFTTFAVSTVCLPLFAFLFCIVWSLLFNFSETTETHCHVPNYLPSVSAAIGGETPQRYLWRLCIGLHSAPRFLVAMAYLKYYQGTPCSNPYYPRLCHINFLLNSCEIFFLMLLTYVSSSENHEVHKLGFMSFMFFSLGYMFVTCTLWRMTRKWSGSPEERTSYAWKKRLFGFYLLMFLASIVVYIWHNMYCEPGVYTLFAFLEYLVVLSNMAFHMTAWWDFGNKELMICSPGDKRI
What is the function of this protein?
Involved in the lipid remodeling steps of GPI-anchor maturation.  Required for stable expression of GPI-anchored proteins at the cell surface (By similarity).
What are the official names of this protein?
Post-GPI attachment to proteins factor 2.
What is the protein family that this protein belongs to?
Belongs to the PGAP2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FL2D_DROPS
Sequence: MSVAAMTMDDQRPLMNSYDKMSTAKYEQNINLISSGASSGISAGGVGGGGVPPSGPASPTPSGSEESHHHPHHPHHSHHHQHHTPNQEQQRQQLQQQEQQHAAVAEAVAAAEQRQRLLEDEIETLKLEQVRMGQICADAQRREKILMRRLANKEQEFQDYVSQIAEYKAQQAPTALALRTALLDPAVNLLFERLKKELKATKTKLEETQNELSAWKFTPDSNTGKRLMAKCRLLYQENEELGKMTSNGRLAKLETELAMQKSFSEEVKKSQSELDDFLQELDEDVEGMQSTILFLQQELKTTRDRIQTLEKDNAQLKQAHTKDDTVAMAPPTTNGTNKMSPPQTPTPSTIGKLEPIDENVALESKAAHPDYLNGDTRSVNNNEQILPSSVPGEHILPDDVNNSNSNGNGNGNAARLARKRNYEEETTTNMVTPTPTPVSYSVEEMTTVREVSTPRILPPKKSKLRGMPTRRSSQLEEELHAAATVAATVATPLILDNSATGMVSEEATAVAQPTLASVESGAVCPESTEAGVVAGPARISTRRRSVRMQQNGAGPLDYST
What is the function of this protein?
Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination.  Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy.  M6A methylation is also required for neuronal functions.  Required for proper inclusion of regulated exons in Ubx transcripts, leading to isoforms Ia/b and IIa/b.
What are the official names of this protein?
Pre-mRNA-splicing regulator female-lethal(2)D.
What is the protein family that this protein belongs to?
Belongs to the fl(2)d family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNP_PHEZH
Sequence: MFDIKRKTIEWGGKTLTLETGRMARQADGAVLATYGETMVLATAVFAKSPKPGQDFFPLTVNYQEKFYAAGKIPGSFPRREGAPSQKETLTSRLIDRPIRPLFVKGFKNEVQVICTVLAHDLENDPDIVAMVAASAALVLSGVPFMGPIAAARVGYVNGEYVLNPTLDEMKESAMDLVVAGTAEAVMMVESEIKELTEEQVLGGVTFAHKGMQPVIDAIIELAEHSAKEPFDFQPDDTDEIAAKVKDLIGGDLRAAYQITGKSERHAAIGAAKEKAMTAFAKSEANPEGYDANKLGGVFKEIEADIVRRSILETGKRIDGRTVDQVRPILGEVGVLPRAHGSALFTRGETQALCVTTLGTGDDEQLIDALEGKYFEKFMLHYNFPPFSVGETGRMGSPGRREVGHGKLAWRALRPMLPSYEEFPYTIRIVSEIFESNGSSSMATVCGSSLALMDAGVPLKKPVSGIAMGLILEKDGFAVLSDILGDEDHLGDMDFKVAGTADGITSLQMDIKIAGITEEIMKKALEQAKGGRDHILAEMNKAMTAPRAELGEFAPKIETIKIPVDKIREVIGSGGKVIREIVEKTGAKIDIGEDGTIKIAAAEQTKIDAAKEWIKSIASEPEVGQIYTGKVVKIVDFGAFVNFFGAKDGLVHVSQISNERVAKVSDVLTEGQQVKVKLLGFDDRGKTRLSMKVVDQETGEDLSKSNEKAEEPADA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_CERS1
Sequence: MAAKDVKFDTDARDRMLRGVNILADAVKVTLGPKGRNVVIDKSFGAPRITKDGVSVAKEIELSDKFENMGAQMVKEVASRTNDEAGDGTTTATVLAQAIIKEGLKAVAAGMNPMDLKRGIDLATSKVVEAIKAAARPVNDSHEVAQVGTISANGEAQIGRFIAEAMQKVGNEGVITVEENKGLETEVEVVEGMQFDRGYLSPYFVTNADKMTAELDDVYILLHEKKLSSLQPMVPLLEAVIQSQKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLQDIAILTGGQVISEDLGMKLENVTIDMLGRAKKISINKDNTTIVDGNGDKAEIDARVAQIRNQIEETSSDYDREKLQERVAKLAGGVAVIRVGGMTEVEVKERKDRVDDALNATRAAVQEGIVVGGGVALIQGGKALDGLTGENPDQNAGITIVRRALEAPLRQIAQNAGVDGSVVAGKVRESNEKSFGFNAQTEEYGDMFKFGVIDPAKVVRTALEDAASVASLLITTEAMIADKPEPKSPAGGPGMGGMGGMDGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_BRUA2
Sequence: MIALPQDRMDQLLKRFSMIESQMANNPDSDTYVKLASEYSELQDVVGKIRELSDARMEASDLAAMRDDASTDAEMRALAVEELPEVEKRIAVLEQDVQILLLPKDAADDKNAILEIRAGTGGLEATLFAGDLFRMYERYAAEKGWRVELVSASEGDAGGYKEIIATVSGKGVFSKLKFESGVHRVQRVPETEAGGRIHTSAATVAVLPEAEDIDIEIRNEDIRIDTMRASGAGGQHVNTTDSAVRITHIPTGIMVVQAEKSQHQNRARAMQILRARLYDMERQKAESERSQARRSQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDRVMEGDLDELVDALISDHQTALLAELGEQP
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1C_NYMAL
Sequence: MKEQKLIHEGLITESLPNGMFWVRLDNEDLVLGYVSGRIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKDSND
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDK_PSEAB
Sequence: MALQRTLSIIKPDAVSKNVIGEILTRFEKAGLRVVAAKMVQLSEREAGGFYAEHKERPFFKDLVSFMTSGPVVVQVLEGEDAIAKNRELMGATDPKKADAGTIRADFAVSIDENAVHGSDSEASAAREIAYFFAATEVCERIR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR18_DANRE
Sequence: MSAPVEVVLSADSAGQLFNCAVYDPHTGSEFLSYRGGNTSSRSLTILNGEYILGAQLGKNYINVWEIQRKDQLQQKIVCPGIVTCLCASPDGLYVLAGIAEAIYLWEVSTGNLLAILSRHFQDLSCIKFTDDSSHFVSGGKDNLAFIWNLSSVVQLDSSRTPEPRHILSRHSLPITDIHCGLMGPQARVATASLDQTVKVWEISSGEMLLSVLFDVGIMSVTFDPCEYFLFCGGSDGNIFQVSLCSTSLSRDKTFQSDSEGNQVFKGHRNLVTCLSVSMDGTVLLSGSNDETVRMWDVQSKQCIWTINHRGPVTNAAIIPAPANMFLSDSHPAVPLPRFSRHLNPSEQGDGTGTGGMSLRLGANTQEPEGTYLEKAEELYSLMCAVTDKSVFGDGENTKVRVSELEEEVRTLKKINKDLYEFSTQLLTKPN
What is the function of this protein?
Involved in left-right determination through controlling the correct clustering and migration of dorsal forerunner cells (DFCs) and Kupffer's vesicle formation (PubMed:21876750).  Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity).
What are the official names of this protein?
WD repeat-containing protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat IPI3/WDR18 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Dynein axonemal particle.