PharMolix/UniProtQA huggingface dataset:
Protein: GLFT_PICTO
Sequence: MPDKEVKIVEAVPNFSEGRDISKIEKIIDSIKNIEGVKILDLNVDPQHNRSVITFTCGIERIIEAGISMIKTAASLIDMEKHSGLHPRFGATDVFPIIPITASMDDCIIASRNLGRLVGSELNIPVYMYSESAMVPERRNLENIRNKNVQYEELKELIKTDKYRPDFGPDSLGSAGAVIIGARPALIAYNIYISTDDIKIGRRIASALRGRDGGLNTLKTLAFYIEARKMVQISMNITDYKKTSIYKIFELLSIECRRYNVYPVESELIGLMPMDALIDVFNYYMKSNITRDKILEYKIFT
What is the function of this protein?
Catalyzes the transfer of the formyl group from N-formylglutamate to tetrahydrofolate (THF) to yield 5-formyltetrahydrofolate (5-CHO-THF) and glutamate (Glu).  The triglutamate form of 5-CHO-THF (5-CHO-THF-Glu3) can also be used as substrate.  It can also catalyzes the transfer of the formimino group from N-formiminoglutamate to tetrahydrofolate (THF) to yield 5-formiminotetrahydrofolate (5-NH=CH-THF) and glutamate (Glu).  It can replace YgfA to catalyzes the irreversible ATP-dependent transformation of 5-CHO-THF to form 5,10-methenyltetrahydrofolate (5,10-CH=THF).
What are the official names of this protein?
Glutamate formimidoyltransferase, 5-formyltetrahydrofolate cyclo-ligase, Glutamate formiminotransferase, Glutamate formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the formiminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRB_ENT38
Sequence: MKTKLLVLAVALSVASAQAADRIAFIPKLVGVGFFTSGGNGAKEAGKELGVDVTYDGPTEPSVSGQVQLINNFVNQGFNAIIVSAVSPDGLCPALKRAMQRGVKVLTWDSDTKPECRSIYINQGTPEQLGSLLVDMASKQVTKPAAKVAFFYSSPTVTDQNQWVKEAKAKIEKEHPQWQVVTTQFGYNDATKSLQTAEGILKAYPDLDAIIAPDANALPAAAQATENLKREGVAIVGFSTPNVMRPYVERGTVKAFGLWDVVQQGKIAVNVADHLLKKGDLNVGDSVDVKGIGVLKVEPNSVQGYQYEAKGNGIVLLPERVVFTKENIDKYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TBX22_HUMAN
Sequence: MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
What is the function of this protein?
Probable transcriptional regulator involved in developmental processes.  This is major determinant crucial to palatogenesis.
What are the official names of this protein?
T-box transcription factor TBX22, T-box protein 22.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHA1_STAA3
Sequence: MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTILIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE
What is the function of this protein?
May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.
What are the official names of this protein?
Alanine dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
Protein: BIOF_GLAP5
Sequence: MNKFTQHLQQLAEIGQKRQLPDIEHQGKFVIARDLTMLNLSSNDYLGLANDAQQVERFLQSIGKNQPLTSSSSRLLTGNFPIYQDFETLLAQRFQRESALLFNSGYHANIGILPAVADKQTLILADKLAHASLIDGIRLSGADFFRYKHNDYLHLEQLLQTHSERYQQVIIVTESVFSMDGDIADLQQLVALKKRYTNVLLYVDEAHAIGVYGQQGLGMAEVFDCIQEIDFLVGTFGKALASMGAYLVCDSEIREYLINTMRPLIFSTALPPINVAWTYFLFEQLPQFTEKRHHLEKLSQILRTEVTKRSEFPLLSETCIVPYILGENQQAVEKADYLQKQGYYCLPIRPPTVPKGTARLRFSLTADLTEQDIMGLISCL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SELD_ALKOO
Sequence: MNQNRRLTQMTKSAGUAAKLGPDVLAQVLCDLPKIEDPNLIVGLETSDDAAVYKINDDMALIQTLDFFTPVVDDPYTYGQIAAANSLSDVYAMGGRPLTAMNIVCFPNCLDPKILNQILKGGADKVLESGALLVGGHTVEDDEPKYGLSITGIVHPKKVWANSTAREGDYLILTKPVGLGVLNTAIKADIATKEQYDGAVKVMSMLNKYAFEALENLDVSACTDITGFGFLGHVYEMAKGSGVSIEIFADKVPLIDGAKELATMGIIPAGMYSNKKHIENEVLKEQDIEDAIEDLLYDPQTSGGLLVSISEKDLPDALENLSLIESNGFSVVGRVLPRSDYAVYVK
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: SLMA_SHESH
Sequence: MAVSPKINRREHILQCLATMLETNPGQRITTAKLAAEVGVSEAALYRHFPSKARMFEGLIDFIEESLLSRINLIMTEEKDTMKRCQLLLQLLLIFSERNPGISRVLNGDALLGENERLRSRVSLIFSKIETHLKQILREKTLREGKGFNLDEAILANLLLAIAEGRIAQFVRSEFKQKPTEHFDQQWIFIQQQLLQS
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS8_ANOFW
Sequence: MVMTDPIADMLTRIRNANMVRHEKLEVPASKIKREIAEILKREGFIRDVEYIEDNKQGILRIFLKYGPNNERVITGLKRISKPGLRVYAKADEVPRVLNGLGIAILSTSQGILTDKEARQKRTGGEVLAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TRPA_BURO1
Sequence: MNRIKQTFAALAEQGRKGLIPFITAGDPDPAKTVEFMHALAAGGADVIELGVPFSDPMADGPVIQRSSERALARGVTLKSVLADVKRFRETDPKTPVVLMGYANPIERMGVDAFAAEAHAAGVDGVLVVDYPPEEAGVFAEKMRAAQIDPIFLLAPTSTDERIADVGKIASGYVYYVSLKGVTGAGNLDVSSIAGKIPAIKSRVPVPVGVGFGIRDAETARAVAEVSDAVVIGSRLVQLLESAAPEGAAAALKTFIAELRAALDGAGNTAR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL9_SPOFR
Sequence: MKQIVANQKVKIPEGLTVHVKSRLVTVKGPRGVLKRNFKHLAVDIRMVNPRVLKVEKWFGSKKELAAVRTVCSHVENMIKGVTKGFQYKMRSVYAHFPINCVTTEGNSVIEIRNFLGEKYIRRVKMAPGVTVVNSPKQKDELIIEGNSLEDVSSSAALIQQSTTVKNKDIRKFLDGLYVSEKTTVEVDEI
What are the official names of this protein?
60S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TGNC_ACIAD
Sequence: MQQFQLYINGKFEDGAAQFDSINPATGEIWAKMPEARTDQVNRAVDAAEQAFYDSSWSGLTASQRGKLLYKLADLVEKSAPRLAALETTDTGKIIRETSSQIAYVAEYYRYYAGLADKIEGSFIPVDKPDMQAWLVREPVGVVAAIVPWNSQLFLSAVKVGPALAAGCTVVLKASEEAPAPLLEFAKLIDEAGFPAGVVNVITGFGPECGAVLSAHPKVAHIAFTGGPETAKHIVRNSAENLAKVSLELGGKSPFIVFADTDINSALNAQIAAIFAATGQSCVAGSRLLIEESIKDEFLQRLAERVQSIKMGLPDDMQTEYGPLCTLKQREKIQQVVQRSVEQGAKLITGGQVCDGAGYYYPPTILDCSGVSDAQSIHTELFGPVLSVDTFSTEAEAIQKANSTPYGLASGVFTSNLTRAHRMTRAIRSGIVWLNTYRVVSPLAPFGGYGLSGHGREGGLSAALEYTTTKTVWLRMSDQPIDDPFVMR
What is the function of this protein?
Involved in the degradation of the pyridine ring of trigonelline (TG; N-methylnicotinate) into succinate and methylamine as carbon and nitrogen sources, respectively.  Catalyzes the NAD(+)-dependent oxidation of (Z)-2-((N-methylformamido)methylene)-5-hydroxybutyrolactone (MFMB) to yield (E)-2-((N-methylformamido)methylene)succinate (MFMS).
What are the official names of this protein?
(Z)-2-((N-methylformamido)methylene)-5-hydroxybutyrolactone dehydrogenase, MFMB dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: SAT2_ARATH
Sequence: MNGDELPFESGFEVYAKGTHKSEFDSNLLDPRSDPIWDAIREEAKLEAEKEPILSSFLYAGILAHDCLEQALGFVLANRLQNPTLLATQLLDIFYGVMMHDKGIQSSIRHDLQAFKDRDPACLSYSSAILHLKGYHALQAYRVAHKLWNEGRKLLALALQSRISEVFGIDIHPAARIGEGILLDHGTGVVIGETAVIGNGVSILHGVTLGGTGKETGDRHPKIGEGALLGACVTILGNISIGAGAMVAAGSLVLKDVPSHSVVAGNPAKLIRVMEEQDPSLAMKHDATKEFFRHVADGYKGAQSNGPSLSAGDTEKGHTNSTS
What are the official names of this protein?
Serine acetyltransferase 2, AtSAT-2, AtSERAT3;1.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLVRB_LITCT
Sequence: APKNIVLFGATGMTGQVTLGQALE
What is the function of this protein?
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, methemoglobin and PQQ (pyrroloquinoline quinone).  Contributes to heme catabolism and metabolizes linear tetrapyrroles (By similarity).
What are the official names of this protein?
Flavin reductase (NADPH), FR, NADPH-dehydrogenase, NADPH-dependent diaphorase, NADPH-methemoglobin reductase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_METC4
Sequence: MSTDLRTRVLSEHHVSRETAASLDLYVAQLTRWQTVKNLVGPATLKEVWHRHIADALQLLSIAPEATRWLDLGSGAGIPGLILALAGKERPGFHVRLVESNARKCAFLSETARLTGAPVTVHNARIEAVIGTLTDTEIVCARALAPLSQLLAWTEPLLTSGTTGLFPKGRDAATELTEAEDEWTFTRDLIPSRTDSQARIVRVTSLSRVDP
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IT1B_PSOTE
Sequence: EPLLDSEGELVRNGGTYYLLPDRWALGGGIEAAATGTETCPLTVVRSPNEVSVGEPLRISSQLRSGFIPDYSLVRIGFANPPKCAPSPWWTVVEDQPQQPSVKLSELKSTKFDYLFKFEKVTSKFSSYKLKYCAKRDTCKDIGIYRDQKGYARLVVTDENPLVVIFKKVESS
What is the function of this protein?
WTI-1B inhibits trypsin stoichiometrically.
What are the official names of this protein?
Trypsin inhibitor 1B, WTI-1B.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: ILVC_PYRAB
Sequence: MVKVVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVLEELMKPIEEHEIEKVGRFIRKMSGLER
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: BIOH_SHEON
Sequence: MNATTSAHHPLHIETIGQGPDLVVIHGWGVNSAVFTPLHEQLSEYRVHYVDLPGFGLSQPIAGNLSTWIDALINNLPTNAIWAGWSLGGLVATQAAIDYPSHIKGLITIASSPCFMAREEEAWPGIPPQVLSMFGEQLGQNLPKTIERFLAIQAMGSETAKEDIKQLRDLVLARPLPDAAALTQGLDMLNQIDLRMQLSSISQPWLRIWGRLDGLVPKRVQPQMPTASHITDVMLAKASHAPFVSHRQEFLQALLPWLTQFKD
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_THEAC
Sequence: MVKMSHGPRSGSRRKLTKSAEERKRSVIGRFMQEFEPGDRVAIDIEPSVHAGMPYHRFQGYTGVVEGPQGDCYKVAVKIDSLTKYVIASPVHLKKIKG
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: NEST_DANRE
Sequence: MELLGVRQPFGPQFQEEKYQMLELNHRLESYLGRVKLLEEENKLLREEIHTLKSSRDPAGQRKAQEEALSQARRMMEEAWRKKDCVELEVENLMEDMEKVSFQRKKVKTAQAEAQRKLTESRKELEEERRAQIWLREKVGQLEKDLMLQMQVHQENMETMQASLKQTKQVLMAPQRVQATSIPDLGQEYGYKAAQAWQEAANNYQKQVGRLEESLNQTKANMTKIYQEKRESQRQVQHLAKELESTRIKRQMLEKHAMQQREEQKEELQHLQAQVNTLELEKDCLGQQIDSLMLDRQHLLQVKMSLGLEVATYRALLDSEGLRIDRPTPNKTSSTVFLDALSKPTGIQSTSQTTAASCLLSSSVSTSHRSIASSRSLLTSAAPSWTLTRGTPQRPPSSTSMTEKTEDHISEETKRSAEESVDQLQQEKVQQDWTLESTLPKTSAEPKPELQPEEIKVEDEANEPQQAHMVESKTDESELTSVPAEQQGSMSQTPETKSWAGHFNDPAEVSEDGKDEDTEVSVEMARISHAPKVAWEEIKSAVEDEKDDASEMDVRSEIISESHTFAYGDAENDSNTLTSSHISQNTNALASSFLEQGTLDSASYFGYEATNENLMKEEELDNVSNISEEVTEQLNSETEAAIDSINEWDRQEESEPENETKVMTSYFEVEEGEMSINTDTKDKTEDDIEREELEVTEREILVQSAGGMLGVDLPNDTDHQDEHNLPQIELNEDQSEAEEENQKEKQCDEDDSPNISASLKTDPGEGDSYSQEHTLADTRPLIRYKSDEETSHHIGETSDSEDEKERIDQGHLNEKRFNTMEDLTEEPDMEVTGKMRLEDLVSNEEAAADDVASVMFQKVSGDHESLDVVVQESERKGNLEKEDSGDADNMRDNKEEDVSVFEQNENQQLTEHQHVHTEQVEDKPVHSHETQEHVNTEFSSTFSERSQQEQLEESSLTMFEDEAATKEAEDSDVSMHTNIDLIDSRSLESEINGQPDIMTSDMANSECNSSEDESPNASQCFQNTSLLAAATPNEQPLTFTNEVSKADYVSDNNDVPEEVLSEEKSTDEPKASQIDDLENFNIWGESTSISDAAQTTHASMDEHSSISPVNENLESSNKIPSVAENIFGHFEEHLERSVESFPEKEVTVMDFENNDLGEEFQSKQMKSEIHSFFSTSLKQDFWSEGKMEMAATYDPAKTEDLNQAMVFGEEWREIGVQSANGDTKEEMEILKIRDDKQKDGQPAQSKIVQSDDSADEGDSWSSGDE
What is the function of this protein?
Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division.  Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).  Required for brain and eye development.
What are the official names of this protein?
Nestin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: LACR_STAXY
Sequence: MQVLWKKFQKKLIDANLAECGIEIGVPNVGYNYTVFQKSVLHIVTQGEGTFSYAGETYHLTAGDIFLLERGMEVEYKPSFSNPWTYYWVGMNGKQILNYLSRCSIVDSHVILGQDTTDIKNIIQLICKLSQSIESNNSNDILIMQYLYQLVYTLQEKFPKIFSVQVDIVNEDIQHAVDFINTNYQKHITVEDVAKSVNITRSHLYKLFKKNLGCSPKEYLTYIRMYHASQLLIHTSTLISDISRQVGYKDPLLFSKNFTKHFEISASEYRHHFSINNKQ
What is the function of this protein?
Transcriptional regulator of the lacPH genes for lactose utilization.
What are the official names of this protein?
Lactose operon transcription activator.
Protein: PGKY3_ARATH
Sequence: MATKRSVGTLKEADLKGKSVFVRVDLNVPLDDNSNITDDTRIRAAVPTIKYLMGNGSRVVLCSHLGRPKGVTPKYSLKPLVPRLSELLGVEVVMANDSIGEEVQKLVAGLPEGGVLLLENVRFYAEEEKNDPEFAKKLAALADVYVNDAFGTAHRAHASTEGVAKFLKPSVAGFLMQKELDYLVGAVANPKKPFAAIVGGSKVSTKIGVIESLLNTVDILLLGGGMIFTFYKAQGLSVGSSLVEEDKLDLAKSLMEKAKAKGVSLLLPTDVVIADKFAPDANSKIVPATAIPDGWMGLDIGPDSIKTFSEALDTTKTIIWNGPMGVFEFDKFAAGTEAVAKQLAELSGKGVTTIIGGGDSVAAVEKVGLADKMSHISTGGGASLELLEGKPLPGVLALDEA
What are the official names of this protein?
Phosphoglycerate kinase 3, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_HPV48
Sequence: MQPETQESLSTRFAAQQEIQLTLIEKESYDLKDHLAYWKAVRLENVIAYYARKEHITKLGLQPLPTLAVTEYKAKEAINIQLLIQSLLKSEFALERWTLAETSAETINSSPRNCFKKVPFIVNVWFDNDERNSFPYTCWDFIYYQDDQNKWHKTEGLVDHNGCYYVDLNGDFVYFTLFQPDAVKYGKTGLWTVRFKNKTISASVTSSSRNTNPSSESRVGLSTSSSSESPRRRPSISENSNTESPTSSTSRLRERRRREPRESGTTDTTPRRRGTKRKLGSDSAPTPSEVGSRSTTLARHGYSRLGRLQEEARDPPLVLFTGQQNNLKCWRNRCTTKYASLFLCFSSVWKWLGPNSDGGAAKVLVAFKSDAQRQVFLNTVHIPKGTTITLGRLDSL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: FLIE_ESCF3
Sequence: MSAIQGIQGVISQLQATAMSARAQEPMPQPTISFAGQLHAALDRISDTQNTARVQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RBL_SYNSP
Sequence: MAYTQSKSQKVGYQAGVKDYRLTYYTPDYTPKDTDILAAFRVTPQPGVPFEEAAAAVAAESSTGTWTTVWTDLLTDLDRYKGRCYDIEPLPGEDNQFIAYIAYPLDLFEEGSVTNMLTSIVGNVFGFKALKALRLEDLRIPVAYLKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFQRWRDRFLFVADAIHKAQAETGEIKGHYLNVTAPTCEEMLKRAEFAKDWNAIIMHDFLTAGFTANTTLSKGCRDNGMLLHIHRAMHAVMDRQKNHGIHFRVLAKCLRMSGGDHIHTGTVVGKLEGDKAVTLGFVDLLRENYIEQDRSRGIYFTQDWASMPGVMAVASGGIHVWHMPALVDIFGDDAVLQFGGGTLGHPWGNAPGATANRVALEACIQARNEGRDLMREGGDIIREAARWSPELAAACELWKEIKFEFEAQDTI
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: PRPC_GIBMO
Sequence: MALNLTSSRRALGSLKPLTRAAFSGVRGYATAEPDLKATLREAIPAKRELLKKVKAHSNKVLGEVKVENTLGGMRGLKAMVWEGSVLDANEGIRFHGRTIKDCQKELPKGKTGTEMLPEAMFWLLLTGQVPSVNQVRTFSRELAEKAQIPEFISKMLDNFPKDLHPMTQFAMAVSALNYESKFAKAYEQGLNKADYWEPTFDDCISLLAKLPTIAAKIYQNAYRGGGALPAEVDLEQDWSYNFAAMLGKGGKENENFQDLLRLYLALHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLQGLAGPLHGLAAQEVLRWIIQMKEAIPANYTEQDVNDYLWSTLNSGRVVPGYGHAVLRKPDPRFEALMDYAAARPEIANDPVFQLVEKNSRIAPEVLKKHGKTKNPYPNVDSSSGVLFHHYGFHETLYYTATFGVSRGLGPLAQLIWDRALGLPIERPKSINLEGILKQVEGQ
What is the function of this protein?
Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate.  Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism.  Has also citrate synthase activity using as substrates acetyl-CoA and oxaloacetate.
What are the official names of this protein?
2-methylcitrate synthase, mitochondrial, Methylcitrate synthase, (2S,3S)-2-methylcitrate synthase, Citrate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: IML2_DEBHA
Sequence: MFKGLRKKASALSLYSQPTRAGGMANDPSSYDKILKQVHDFETAFKAMDYLLDDRTQDGIDLLQEQQKRHVKTESQQPAAIFPLALGVMEFIEATLGFEPEVMERAHQTLSEAEAASMNNVKYNVRYSLGTSHIYPPGTEFQVTNAESTLLNALLMLLQESNGVVESAKALFKLRKAYQTLDSIYKKIKESEPVFNKNLAKLKKEASLQHEGNSANVSTVDLPGYSNQSSRGGSSASLPQDVKLLKNLETVYQMRKSRIEGTSLNDPSQALNVNMYAATSSGESSVSVASAVNSDSGGRPESPRATTLSQNAKFRNPIPSSADDEFDDEDDEFSDASDTFHSFGNLSIPHSMHKSSSLANSQVLDNAESFVSGANSSSISLRNSDQEDNHMHVSTVDEYIHSGVQLCFGILQVVLSLIPPTIGKVLSIVGFRGDRETGLKMLWRTAITSRNIHGELALLCLLVFYDGPIQFIDDGYQLPGQEDANVSEVISIDKKSNISDKELEIILKNPALYTPQLLTKVRGYFPHNALWLLQEGRMLAAQGQLVKAATLMQSFTDNPETKINMQQVEALLIFDRAMLYAFKHDYDEAARDFIYLLDINSWSKSIYLFFAGSCYLEKWRMIKLGMIEVEDREKSLKYYGDQAELYLKKAPTYVPGHGINASNKKGGIGGGNKQMPFDKFLLRKLQHIENCQKKHPKLSFLNCFGTSPIHELIYFWNGYNRMNETELKLTLTLLGYSGAVNSDYSANNNEQNFAKFEENEDEAMIRYLFQSITLRSLNRLSEGVSLLDSHVISKFVTQDSPNMPFKFIKMTYSPYLYPTALYERSMFVWLLRTSKKSANLREAIEESKSWLKKSEMVGDGDYELSNRTGMKIKAAGDRLDQFKTQI
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein IML2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.
Protein: RS7_CAMJJ
Sequence: MRRRKAPVREVLPDPIYGNKVITKFINSLMYDGKKSTATTIMYGALEAIDKKGGEKKGIDIFNDAIENIKPLLEVKSRRVGGATYQVPVEVRPARQQALAIRWIISFARKRSERTMIDKLAAELLDAANSKGASFKKKEDTYKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: AMPI_ANTMY
Sequence: AEPLASQLKEPIAGGGWWAA
What is the function of this protein?
Inhibits trypsin and chymotrypsin.
What are the official names of this protein?
Protease inhibitor, AmPI.