PharMolix/UniProtQA huggingface dataset:
Protein: CPAT_ASPOZ
Sequence: MGHQEEPPRICKTPSGHEQGEGPAEKTSKPSTEEVGWDGPTDPARPVNWSRKKKWWNMGIISYLTFLTPLTSSIVAPAQGLVMKDFHSTNRTLASFVVSIYLVGFAVGPLFLAPLSEIYGRLRVYQVGTFIFTIWNIAGAVAPNVGALLVFRLFAGISGSGPVTLGAGSVADMFARQERGVAMSLYGLGPLLGPVIGPIAGGYLSQAQGWRWVFWLLAIVSGVAVILVLFVLSESYEPVLLRQKAKRIRRENSSVEVNAGQALKLDSRKVFIQAITRPTKLLFLTPNVALFSLYTGVVFGYLYLLFTTVTEVYETTYHFSQGATGLVYIGIGVGALIGISCFGALSDKIQNILIARNNGQAEPEFRLPPLIPGSFLIPIGLFWYGWSTQMHIHWIMPIIGLGWVGCGMIATLLPIQAYLVDAFGEYAASAIAANTVVRSIVGAFLPLAGPSMYATLGLGWGNSLLGFVALGLLPVPVVFYFYGKKIRMNSRYQVSV
What is the function of this protein?
MFS transporter; part of the gene cluster that mediates the biosynthesis of the fungal neurotoxin cyclopiazonic acid (CPA), a nanomolar inhibitor of Ca(2+)-ATPase with a unique pentacyclic indole tetramic acid scaffold.
What are the official names of this protein?
MFS transporter cpaT, Cyclopiazonic acid biosynthesis cluster protein T.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 095R_FRG3G
Sequence: MGIKGLKPLLRSYGVHEYTVPLSQMSGKTIAVDGTFLLHKYKNCHSVPWHYLTLYTLSNLRLRNVKVLFIFDGMSPPEKSREKSNRRCRKQALMEKGTLVKAQLEVWKKDGGEQAPELAAVSERLVKTRGLDPSLTDPETVQVLTDYVDNMSRDTRVTSDDYELMRRSLDAFGFPYADAPDEAELCCVRVVQMGIADAPMTIDSDALACGALHGVDVVYTDLHGETLTAMSTSKSKEALGLNGEQFMDLCVMCGTDFNQRVHKLGPVTALKLIKAHGSIENIPSAAPSMSCLEAVRTREILSGGDMESRRKDYEAMVQKPVSAELIRSVFPPEFLDKLLHENWQLRDAMKRMAPEAFEKCKRK
What is the function of this protein?
Probable endonuclease.
What are the official names of this protein?
Putative RAD2-like endonuclease 095R.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: XRN3_ARATH
Sequence: MGVPSFYRWLAEKYPLLVADVIEEEPVEIEGIKIPVDTSKPNPNNLEYDNLYLDMNGIIHPCFHPEDRPSPTTFEEVFQCMFDYIDRLFVMVRPRKLLYMAIDGVAPRAKMNQQRSRRFRSAKDASDAAAEEERLREEFEREGRRLPPKVDSQVFDSNVITPGTEFMGVLSIALQYYVHLRLNHDVGWKNIKVILSDANVPGEGEHKIMSYIRLQRNLPGFDPNTRHCLYGLDADLIMLGLATHEVHFSILREVVYTPGQQERCFLCGQMGHFASNCEGKPKKRAGESDEKGDGNDFVKKPYQFLHIWVLREYLELEMRIPNPPFEIDLERIVDDFIFICFFVGNDFLPHMPTLEIREGAINLLMAVYKKEFRSFDGYLTDGCKPNLKRVEQFIQAVGSFEDKIFQKRAMQHQRQAERVKRDKAGKATKRMDDEAPTVQPDLVPVARFSGSRLASAPTPSPFQSNDGRSAPHQKVRRLSPGSSVGAAIVDVENSLESDERENKEELKTKLKELIREKSDAFNSDTTEEDKVKLGQPGWRERYYEEKFSVVTPEEMERVRKDVVLKYTEGLCWVMHYYMEGVCSWQWFYPYHYAPFASDLKDLGEMDIKFELGTPFKPFNQLLGVFPAASSHALPERYRTLMTDPNSPIIDFYPTDFEVDMNGKRFSWQGIAKLPFIDERRLLEAVSEVEFTLTDEEKRRNSRMCDMLFIATSHRLAELVFSLDNHCRQLSARERVDFKVKIKPKLSDGMNGYLTPCSGETHPPVFRSPMEGMEDILTNQVICCIYRLPDAHEHITRPPPGVIFPKKTVDIGDLKPPPALWHEDNGRRPMHNNHGMHNNHGMHNNQGRQNPPGSVSGRHLGNAAHRLVSNSLQMGTDRYQTPTDVPAPGYGYNPPQYVPPIPYQHGGYMAPPGAQGYAQPAPYQNRGGYQPRGPSGRFPSEPYQSQSREGQHASRGGGYSGNHQNQHQQQQWHGQGGSEQNNPRGYNGQHHHQQGGDHDRRGRGRGSHHHHDQGGNPRHRY
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity (PubMed:11106401).  Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor.  Degrades miRNA-derived loops, excised during miRNA maturation in the nucleus.  Required for proper development (PubMed:17993620).  Involved in pre-rRNA processing.  Involved with XRN2 in the 5'-end exonucleolytic processing of 5. 8S and 25S rRNAs.  Contributes with XRN2 to polyadenylation-dependent nuclear RNA surveillance.  Involved in the degradation of aberrant polyadenylated pre-rRNA through 5'-end processing (PubMed:20338880).
What are the official names of this protein?
5'-3' exoribonuclease 3, AtXRN3, Protein EXORIBONUCLEASE 3.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRFA_VIBPA
Sequence: MSIKHWMSAPIAVATLFASQLLLAGSVLAAENNDRLDPRNDAFEQKHPDQYHSWKATSESKHIEDALSEDPNMVILWAGYGFAKDYNKARGHFYALDDVRQTLRTGAPADENSGPMPMACWSCKSPDVARVIEERGEDGYFSGKWARLGSEIVNPIGCSDCHDTRSEKFNQGEPELALTRPYVERAFDVIGKNFDDQSRLDKQASVCAQCHVEYYFTGPTKAVKFPWDMGTTVGDMEKYYDALDFKDWTHAVSKAPMLKAQHPGFETWREGIHGKNKVVCVDCHMPKVTKADGTVYTDHKVGNPFDRFEDTCAQCHTQTKEQLRNIVSSRKALVLNMKLTAEKQIVAAHFEAGEAWKAGATEEEMKPILQDIRHAQWRWDYAIASHGVHMHAPEVALEVLGTAVDRAADARTKLVRLLATKGITEPVQIPDISTKAKAQEALGMDMEKMNADKKHFLDTVVPDWDKAAAEREATY
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PURK_MYCLE
Sequence: MMAVPSRCSLGVAPLVAMVGGGQLARMTHQAAIALGQTLRVLATAADEPAAQVTPDVVIGSHTDLEDLRRVALGADALTFDHEHVPTELLDKLVAEGINVAPSPQALVHAQDKLVMRRRLAALGAAMPRFMALDSVDDLAEIDAFAQRLTGSKDAPMVVKAVRGGYDGRGVQMVRDSAHAREVASGYLVDGMPVLVEERVELRRELSALVARSPFGQGAAWPVVETVQRDGICVLVVAPALALADDLASAAQQLALRLAAELGVVGVFAVELFETADGALLVNELAMRPHNSGHWTMDGARTSQFEQHLRAVLDYPLGETDAVAPVTVMVNVLGAPQPPTLSVVTMDERLHHLFARMPDARVHLYDKVERPGRKVGHINFRGTDKDRKNPTKLRERAELAAHWLSHGQWTDGWDPHRAGDDVVEISLACGGRNDAQRQR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide synthase, N5-CAIR synthase, 5-(carboxyamino)imidazole ribonucleotide synthetase.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: HSLV_BACHK
Sequence: MGNFHATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEMFEGKLEEYNGNLQRAAVEMAKQWRGDKMLRQLEAMLIVMDKTTMLLVSGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLEIAGDICVYTNHNIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_BACC2
Sequence: MSKVIETKQQVVTEIADKLRASKSTIVVDYRGLTVSEATELRKQLREAGVEFKVYKNSLTRRAAESAEMAELNEFLTGPNAIAFSNEDVVAPAKVLNDFAKNHEALEIKAGVIEGKLVTLDEVKAIATLPSREGLLSMLLSVLQAPIRNLALATKAVAEQKEEQGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SYR_THET2
Sequence: MLRRALEEAIAQALKEMGVPARLKVARAPKDKPGDYGVPLFALAKELRKPPQAIAQELKDRLPLPEFVEEAIPVGGYLNFRLRTEALLREALRPKAPFPRRPGVVLVEHTSVNPNKELHVGHLRNIALGDAIARILAYAGREVLVLNYIDDTGRQAAETLFALRHYGLTWDGKEKYDHFAGRAYVRLHQDPEYERLQPAIEEVLHALERGELREEVNRILLAQMATMHALNARYDLLVWESDIVRAGLLQKALALLEQSPHVFRPREGKYAGALVMDASPVIPGLEDPFFVLLRSNGTATYYAKDIAFQFWKMGILEGLRFRPYENPYYPGLRTSAPEGEAYTPKAEETINVIDVRQSHPQALVRAALALAGYPALAEKAHHLAYETVLLEGRQMSGRKGLAVSVDEVLEEATRRARAIVEEKNPDHPDKEEAARMVALGAIRFSMVKTEPKKQIDFRYQEALSFEGDTGPYVQYAHARAHSILRKAGEWGAPDLSQATPYERALALDLLDFEEAVLEAAEEKTPHVLAQYLLDLAASWNAYYNARENGQPATPVLTAPEGLRELRLSLVQSLQRTLATGLDLLGIPAPEVM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_ZYMMO
Sequence: MPSANFRLARRGLLFVISSPSGAGKSTIARRILAEDDEIHLSVSVTTRPKRPGEVDGVDYHFVDVPTFKKMVAENQLLEWAHVFDNRYGTPRAPVEEMLHKGQDVLFDIDWQGAQQLWQQASGDTIRVYILPPSFEELERRLRGRGTDSEEVIQKRMARAASEISHWDGYDYVLINDDMDECVKQVKNILTVERIKRRRQIGLIGFTRKLLAPPED
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFNW1_HUMAN
Sequence: MALLFPLLAALVMTSYSPVGSLGCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFRFPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHLETCLLQVVGEGESAGAISSPALTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTNMQERLRSKDRDLGSS
What are the official names of this protein?
Interferon omega-1, Interferon alpha-II-1.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEF_OCEIH
Sequence: MITMKDIVREGHPSLTRSAAVVEVPLSKDDKQLLEDMMQFLKNSQDEEIAEKYELRAGVGIAAPQLGIEKQIIAIHFEDIDGKLYSMGLVNPKIISHSVEQSYLSSGEGCLSVDRPVEGYVPRHARITIKATDINDQPVKLRLKGYPAIVFQHEIDHINGIMFFDRINTEDPFNIPENSSPIQ
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ISPG_LISMF
Sequence: MNERIFRENTRPVQVGNLTIGGSEELTIQSMTTTKTHDVEATVAEIHRLEEVGCQIVRVACPDERAANALSAIKKRIHIPLVADIHFDYRLALKAIDAGVDKIRINPGNIGRRDRVEKVVNAAKAKNIPIRIGVNAGSLEKKIIQKYGYPTAEGMVESALAHIKILEDLDFYDIIVSLKASDVNLAIEAYDKASRAFNYPLHLGITESGTQFAGGIKSAAGLGAILSLGIGNTLRVSLSADPVEEIKVAREVLKSFGLSSNAAMLISCPTCGRIEIDLIRIANEVENYIATIKAPIKVAVLGCAVNGPGEAREADIGIAGSNGEGLLFRHGKIIRKVPEAIMVEELKKEIDILAEEYFEKKTDLESLR
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: C_RINDR
Sequence: MSTKAWNASRLSGPDPSTPWSLRKPLQHGSRPPKGKRLTVCPPTRPKQTIRISASHASQQLDQAKAACLAVTIKDLEEATAVMRSWEHSLVTPQCIAPRYSIIMFMITAVKRLRESKMLTLSWFNQALMMVSKSGEEMRNLRTAMWILANLIPREVLPLTGDLLPSLQQQEPPMLKQ
What are the official names of this protein?
Protein C.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus protein C family.
Protein: KCY_SHIDS
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGSSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_VIBCH
Sequence: MSSHTPVVTVDGPSGAGKGTLCMLLAKKLGFQLLDSGAIYRVLALAALHHGVDLESEDALVPLATHLDVQFIAEGDLVKVILEGEDVSRELRKEETGMAASKVAALPRVREALLRRQRAFASGIGLVADGRDMGTVVFPAAEAKIFLDASAEERARRRFKQLQLKGLDVKFDALLSEIQERDDRDRNRAVAPLRPAEDALVLDSTTLTIDEVVEQALQYIESKLV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSP4B_HUMAN
Sequence: MKTSVLLAITAMCSDDWLLVRMKIRPFDKNTDIRIGDIHLRDNCPVTRLLSFNYAFSYPVTSCGIKKIMFQTNDDAILSEISYKPRLHTTYEFPVVCFVKRLKFPSVMHFGMSGFDAHTLKEIPQKTKGQESPTPTQSKTWTLNFNSVNKEQLSKKSLYQ
What are the official names of this protein?
Oocyte-secreted protein 4B.
What is the protein family that this protein belongs to?
Belongs to the PLAC1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VE2_HPV41
Sequence: MSQMERLLERLDYIQEQILTLYEKDSVDLEDHIRLWNLLRRENAIWYVLRQEGHARVGGRAVPAMTVSEANAKFAIEMQIKLESLKASPYAAEGWSLQETTKERYLAEPSRTFKKLGQPVTLMFDNDPENLTEVVLWKWVYYITPTDEWYKARGGIDDTGIYYIDHESVKMYYVRFDMEAENFSETGTVTYRLGSALVNVPEPVTVTDSSSTRERTPKVLRPQGSRRRRNEETGEPVAPAPKRRRGAYGRRSSPKAQRRTAASPVSRGNGGSSDFTSGESDEGHRVRHRALRKKTAGVAPAEGHYLVGAKGPVNSLRCLRYKWKNKYSGDIMYLGTTFTWTESDGTERCGSGRFFCAFSNETKREKFLKSVKIPKNIGLFRAHAEKL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: DDL_SYNR3
Sequence: MSSQQSKVVGLIFGGASGEHDVSIRSAATVAEGLSSGANKERYRVQHVYIDRQGRWWGDATARQVLSSGQALADDGSRPGFSGFPDGCLEVEIWYPVLHGPNGEDGTIQGLFSLMQRPFVGSGVLGSAVGMDKLAMKAAFSAAGLPQGPYRPVLASELVSNSQLLEELETQLGYPCFIKPANLGSSVGISKATNRSELQAGLDLAASHDSRLLVEKGLQVRELECAVLGGQHLKASVLGEVSFDADWYDYETKYSSGLSSTQIPADLPEAISSRAQHLAIEAVQAVGASGLSRVDFFYEEASGNLLINEINTLPGFTSQSMYPMLWKASGVPLEELVHQLLELAQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPAR_AOTTR
Sequence: MGHPLLLPLLLLLLHTGVPASWGLRCMQCNGHGNCRVEECALGQNLCRTTSVRHWEEGEEVEMVEKSCTHSEKTNRTMSFRTGVRITTLTEAVCGLDLCNQDSSGPAVTFPRSRFLECISCGSSDMSCERGRHQSLQCTSPKEQCLDMVTHRTSEAEEGRPKDDHHIRGCGHLPGCPGIAGFHSEDTFHFLKCCNTTKCNGGPILSLANLPKNGHRCYSCQGNSTHGCSSENTVLTDCRGPMNQCLEATGIYEPLSESYMVRGCATSSMCQHDHVSDAFSMSHIDVACCTENDCNNPAEDIQHRSEAAPQPGPAHLSLTITGLMTARLWGGTLLWT
What is the function of this protein?
Acts as a receptor for urokinase plasminogen activator.  Plays a role in localizing and promoting plasmin formation.  Mediates the proteolysis-independent signal transduction activation effects of U-PA.  It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity).
What are the official names of this protein?
Urokinase plasminogen activator surface receptor, U-PAR, uPAR.
What are the subcellular locations of this protein?
Cell membrane. Cell projection, invadopodium membrane. Cell membrane; Lipid-anchor, GPI-anchor. Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin-dependent manner.
Protein: MSP63_CAEEL
Sequence: MAQSVPPGDIQTQPGTKIVFNAPYDDKHTYRIKVINSSARRIGYGIKTTNMKRLGVDPPCGVLDPKEAVLLAVSCDAFAFGQEDTNNDRITVEWTNTPDGAAKQFRREWFQGDGMVRRKNLPIEYNP
What is the function of this protein?
Central component in molecular interactions underlying sperm crawling.  Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
What are the official names of this protein?
Major sperm protein 63, MSP.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cytoskeleton.
Protein: DCUP_HAHCH
Sequence: MSELKNDRFLRALMRQPVDVTPVWMMRQAGRYLPEYRASRARAGSFMDLCKNAEFACEVTLQPLERFELDAAILFSDILTIPDAMGLGLYFETGEGPRFKKTVRTEADVNALHMPDADTDLGYVMNAVRTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFREIKKLAYGQPELLHLLLDKLADSVADYLNAQIRAGAQAVQIFDTWGGALTAAGYLEFSLAYMKKIVSKLQREADGRPVPVILFTKNGGQWLEHIADAGADALGLDWTTEISEARRRVGDRVSLQGNMDPAALYAPPAAIRDQVSRILASFGSGSGHVFNLGHGITPDVDPEHAKVFIDAVHELSAPYHQNA
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_SHIBS
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYAPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YII9_YEAST
Sequence: MQRTRELESSVAIDQTEVPRSRFFIMVKKLSRVADIVYIVDTFLIPPLHPLKKQHPKVAKFLKVQLVFDLISLFIFATHQLLLLEDGNFGKHYFKRKTKRCSKFSCSRCNANAHHPKWFKFKHSLLCLGTFCFGVYSLVKINKFFKTDQTVDLNRLLELFFWQLNAILNMKLFAFYGDHLESHSAPLDVYEDSFANKSSSGGDEV
What are the official names of this protein?
Uncharacterized membrane protein YIL089W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSBD2_ACAM1
Sequence: MTVALGRVQERGWFDVLDDWLKRDRFVFIGWSGLLLFPCAFLSIGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPADSMGHSLLLLWGPEARGDFTRWCQLGGMWNFVTLHGAFGLIGFMLRQFEIARLVNVRPYNAVAFSGPIAVFVSVFLMYPLGQSSWFFAPSWGVASIFRFLLFVQGFHNLTLNPFHMMGVAGILGGALLCAIHGATVENTLFEDTKDANTFSGFSPTQSEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWASAIGLVGIALNMRAYDFVSQEIRAAEDPEFETFYTKNILLNEGLRAWMAPQDQIHENFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein 2, PSII D2 protein 2, Photosystem Q(A) protein 2.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: YQJ3_CAEEL
Sequence: MRRITCCFPIKIHRRQPPSPPSTITLSSYEYSSLAVGIISDLKEEGCDTLLVKLQKDANRKIGMGVGVRDRGILITTVVPGSVAAEKLKVGDRILAVNGRPILDQRSVVKSVKASGQRLYLQIARPHKVHK
What are the official names of this protein?
PDZ domain-containing protein C52A11.3.
Protein: RIMP_RHIL3
Sequence: MSDLTNADNEREPRLITETGLDQRLADIIEPVLVDLGFRLIRVRMMNQNGATMQVMAERNDGTMTVQDCEEVSMAISPVLDVEDPVDKEYHLEVSSPGIDRPMVRKSDFVRWQGHLVKCETSILIDNRKRFRGKIVEAGTDGFTLERDQIAYGEEQKVTIPFTALSDAKLILTDDLIRDALRADKLAKAQAANQNEADDEE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1453_METJA
Sequence: MISEVVVTTRKNNRDNKAPIGVYFKDKKVIMHLFSGSHTYENLLTEDYFSVNVVPPIEIAKAVLDDEDDYLYYNDIPYLKSSYYAIFYKVIERKFVDREDKFGKNRLMILEGEEIKRIYLNNIPKPYNRADGLLVEIAVIYSRLANKNIKINEDDKKEMINDIRKYFSIIKKVGGREHKQLAEIMLRNLNLL
What are the official names of this protein?
Uncharacterized protein MJ1453.
What is the protein family that this protein belongs to?
To M.thermoautotrophicum MTH863.
Protein: CRVP_HELHO
Sequence: MILLSLYLCLAAMLHQSEGEASPKLPGLMTSNPDQQTEITDKHNNLRRIVEPTASNMLKMTWSNKIAQNAQRSANQCTLEHTSKEERTIDGVECGENLFFSSAPYTWSYAIQNWFDERKYFRFNYGPTAQNVMIGHYTQVVWYRSYELGCAIAYCPDQPTYKYYQVCQYCPGGNIRSRKYTPYSIGPPCGDCPDACDNGLCTNPCKQNDVYNNCPDLKKQVGCGHPIMKDCMATCKCLTEIK
What is the function of this protein?
Alters a variety of ion channel activities, including voltage-gated potassium channels (Kv) (PubMed:8071987), voltage-gated calcium channels (L-, N-, and P-type) (Cav) (PubMed:8817251) and ryanodine receptors (RyR) (PubMed:7647234).  Is toxic to mice (causes lethargy, partial paralysis of rear limbs and lowering of body temperature).
What are the official names of this protein?
Cysteine-rich venom protein helothermine, CRVP HLTx.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: ALKB_CAUVC
Sequence: MAVVRRAVAARGLQMIAKPLTVVPGFDVWPGLLDISAQRALVEAVLAGAEQAPFSNYRTAYGKPMSVAMTALGSLGWTSDARGYRYVDRHPETGRPWPDMPPALLDLWTVLGDPETPPDSCLVNLYRDGARMGLHQDRDEADPRFPVLSISLGDTAVFRIGGVNRKDPTRSLRLASGDVCRLLGPARLAFHGVDRILPGSSSLVPGGGRINLTLRRARTA
What is the function of this protein?
Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation.  Has highest activity towards 3-methylcytosine.  Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine.  Accepts double-stranded and single-stranded substrates.  Requires molecular oxygen, alpha-ketoglutarate and iron.  Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (By similarity).
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase AlkB homolog, DNA oxidative demethylase AlkB.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
Protein: PSBM_CHLSC
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CBP_ORYSJ
Sequence: MAGYPPNPGSGYPYGGAGGYGAPPPPYGSSPAPSAPPYGAKPPKEGKTSSSSAPYYGGGGGYGAPPSTQPYGSGGGYGAPPSSQPYGAPYGAPPPSSAPYGAPGGYGSPFASLVPSAFPPGTDPNVVACFQAADRDGSGMIDDKELQSALSGYSQSFSLRTVHLLMYLFTNTNVRKIGPKEFTSVFYSLQNWRSIFERFDRDRSGKIDATELRDALLSLGYSVSPTVLDLLVSKFDKTGGKNKAIEYDNFIECCLTVKGLTEKFKEKDTAFSGSATFTYEAFMLTVLPFLIA
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Calcium-binding protein CBP, OsCBP.