PharMolix/UniProtQA huggingface dataset:
Protein: U76E2_ARATH
Sequence: MEEKQVKETRIVLVPVPAQGHVTPMMQLGKALHSKGFSITVVLTQSNRVSSSKDFSDFHFLTIPGSLTESDLQNLGPQKFVLKLNQICEASFKQCIGQLLHEQCNNDIACVVYDEYMYFSHAAVKEFQLPSVVFSTTSATAFVCRSVLSRVNAESFLIDMKDPETQDKVFPGLHPLRYKDLPTSVFGPIESTLKVYSETVNTRTASAVIINSASCLESSSLARLQQQLQVPVYPIGPLHITASAPSSLLEEDRSCVEWLNKQKSNSVIYISLGSLALMDTKDMLEMAWGLSNSNQPFLWVVRPGSIPGSEWTESLPEEFNRLVSERGYIVKWAPQMEVLRHPAVGGFWSHCGWNSTVESIGEGVPMICRPFTGDQKVNARYLERVWRIGVQLEGDLDKETVERAVEWLLVDEEGAEMRKRAIDLKEKIETSVRSGGSSCSSLDDFVNSM
What is the function of this protein?
Possesses low quercetin 3-O-glucosyltransferase and 7-O-glucosyltransferase activities in vitro.
What are the official names of this protein?
UDP-glycosyltransferase 76E2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: SYDND_METTH
Sequence: MLLGDLRRTHYSKDIEPEMDGDEVTVMGWVHEIRDLGGIIFVLLRDRDGLIQITAPSKKIEKDLFKSIRKLKKESVVAFGGTVQESGKAPGGFEIIPSFLKVLNISKQPLPLDPTEKVKAEIDTRLDARFLDLRKPSVSAIFKIKSRMLHSVRVFLEEQGFLEINTPKLVASATEGGTELFPITYFEREAFLGQSPQLYKQIMMSTGLDRVYEIAPIFRAEEHDTLRHLNEVISIDIEASFVDHEDVMKILENLVVRVIEDVNEHCTDALETLGRTLEVPETPFERLEYDEAVEMVNSKGVPMKHGEDLPRAAEKALGEIMDGYYFITSWPTAIKPFYVMPDEDDPERSHAFDLMYRDLEISSGAMRVHQHDLLVEKIKRQGLNPDSFESYLSAFEYGMPPHAGWGLGAERFNMTLTGLKNIRETVLFPRDRRRLTP
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_SOLUE
Sequence: MQIEKVYEPQRFEPHWAQWWIDSNIFRANPESPGRVFSLVIPPPNVTGVLHIGHMLEHTEIDVSTRWHRMLGDNTLWLPGTDHAGIATQMVVARQLKEEGINYRDLGREKFEERVWQWKAQSGDTIKRQMVRLGASCDWSRERFTLDPGLSRAVREVFVSLYERGLLYRGEYMTNWCPSCNTAISDLEVAHADVAGHLWHIRYPVNGMPGRFVTVATTRPETMLGDTAIAVNAKDPRYQDLHGKTVQLPLMDREIPIILDDLADPQFGTGVVKVTPAHDPNDFEAGKRHNLAKIQVIDNNARMTAAAGPYAGLDRFDARKRVVSALEEIGALVKVEDYPLSLGKCDRCKTPVEPLISTQWFVKTKPLAEKAIAVVESGEIGFVPQNWTKTYYEWMYNIRDWCVSRQLWWGHRIPAWHCGECKEIIVAREAPKACPRCASENLTQDTDVLDTWFSSGLWPFSTLGWPDQTADLAKYYPTTLLITGFDILFFWVARMVMFGLEFMGEVPFKQVYIHGLVRDADRQKMSKTKGNVIDPLVVTEKYGTDAVRMALLQGAAPGTDIVLTEERMESSRAFANKIWNAARFLFMNADQSAAAPAEPTIEDRWIVSRLNAAAETANRAIEQYRYHELAQELWKFFWHEFCDWYLELKKVSATGWGNAVAAFETALRLLHPAMPFLTEELWQRLERKEGDPKSIALAQYPQYRAELADSEAEKEVAIIQEIVTLARTLRTESKLDPKQQLKGALYCRTASLAIAQRHADAIQKIARTTLEFKAEAPPKADVIRSTVEFDLVLDVPKVEEDPARKQKEREQLEKNIANSKRQLGDEVFLSKAPAKVVDSIRAKLVDYEAQLAKML
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_EUGGR
Sequence: MKYPALIDYKNVNILRRFINFQGKIIPKRLNKPKLTYKQHRLLRKSVKQARYLGLLPFKTKDFF
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SEC4_CANAL
Sequence: MSGKGTSSRAYDMIMKLLLVGDSGVGKSCLLLRFVEDKFNPSFITTIGIDFKIRTIESKGKRIKLQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTDSRSFENVENWFQTVTQHANEDAQIFLVGNKCDDEVNRQVSKEQGQELAAKLNVPFLEASAKSNENVDSIFYELASIIQEKHVEENIGGVGGASGAGGIDVSQNNSGAKNNCC
What is the function of this protein?
Involved in exocytosis.  Maybe by regulating the binding and fusion of secretory vesicles with the cell surface.  The GTP-bound form of SEC4 may interact with an effector, thereby stimulating its activity and leading to exocytotic fusion.  SEC4 may be an upstream activator of the 19. 5S SEC8/SEC15 particle.  SEC4 probably interacts directly with SEC8; it could serve as the attachment site for the SEC8/SEC15 particle (By similarity).
What are the official names of this protein?
Ras-related protein SEC4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Lipid-anchor; Cytoplasmic side. Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MEF2C_MOUSE
Sequence: MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDLMISRQRLCAVPPPSFEMPVTIPVSSHNSLVYSNPVSTLGNPNLLPLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNIQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLSIKSEPVSPPRDRTTTPSRYPQHTTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPSPDERESPSVKRMRLSEGWAT
What is the function of this protein?
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes.  Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development.  Enhances transcriptional activation mediated by SOX18 (PubMed:11554755).  May also be involved in neurogenesis and in the development of cortical architecture.  Isoforms that lack the repressor domain are more active than isoform 1 (By similarity).  Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission.  Crucial for normal neuronal development, distribution, and electrical activity in the neocortex.  Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis.  Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells.
What are the official names of this protein?
Myocyte-specific enhancer factor 2C, Myocyte enhancer factor 2C.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, sarcoplasm.
Protein: ISAA_STAAS
Sequence: MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
What is the function of this protein?
Is able to cleave peptidoglycan.
What are the official names of this protein?
Probable transglycosylase IsaA, Immunodominant staphylococcal antigen A.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. IsaA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CP11B_LITCT
Sequence: MLEKTAARQIGSCLMRCRTLDTTSPLWTGFSRLSTAPLIHEAREDGSLASQTLPYEAIPTTGRSAWFNLFQFWRKNSFQHMHLAMEENFQNLGPIYREKLGTHNSVNIMLPQDVARLFQSEGIFPRRMTMEAWSKHRELRNHKQGVFLLNGEAWRSDRIILNKEVLSLAGVKKFLPFLDEAAADFVTFMKKRMSKNTRGSLTVDLYADLFRFTLEASSYVLYGQRLGLLEEHPNADTLRFISAVETVLKTTLPLLYYPHQILQLFQTRLWNEHMHAWDVIFEQADRCIQNIYQEYCLGQERGYSGIMAELLLQAELPLDSIKANITELMAGGVDTTAMPLLFTLFELARNPSVQRELREEIRKAEAQNPNDLNQLLNSLPLLKGAIKETLRLYPVGITVQRHLIKDIVLHNYHIPAGTLVQVGLYPMGRSPLLFQDALRYDPARWLKREDTNFKALAFGFGSRQCIGRRIAETEITLFLMHMLKNFQIDTVSKDDIKTVFGFILMPEKPPLLTFRPI
What is the function of this protein?
Has 11 beta-hydroxylation, 18-hydroxylation activities and aldosterone synthetic activity.  Catalyzes the final steps of glucocorticoid and mineralocorticoid biosynthesis.
What are the official names of this protein?
Cytochrome P450 11B, mitochondrial, CYPXIB, Cytochrome P450C11, P-450(11 beta,aldo), Steroid 11-beta-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: GET1_DEBHA
Sequence: MFDISSSNLLISVLVVLFAKQLINAVGKATLENIGWSAYCKVAPKLGDSKFIALDQKNVELAKVSKERKSISAQDQYARWTKLNRQFDKLTGEINKLKEETSASRSYISKYIGYMILVTTTLPIWFFRVWFRKAVLFYFPTGVLPHYLEWFLALPFITTGGVGLTIWMSAVNNVVSSVIFLVKFPFEKEVPFPSKEVGNEKTSINKEEVSGTPAAN
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: ATP6_SORC5
Sequence: MPEHTGFLTYLLAQLPGLRENARNIGKTFIGHHTVDYRGTEPIFMSLLIMVLFVLLASEVRGQYRRLNESVIPEDKLTLRTFFEAFFGYFYGMARDVMGPANAKRYFPLIGGSAAFIFFSNASALIPGVNPPTSNLNITIGCAVVVFVLFNYYGLKENGWSYVAHLAGPKWYLAPLIFPIEVISTCVRPVTLSIRLMLNIGVDHLVASIFLGLVALFVPVPLMFLAIIVIVVQTLVFCLLSCIYIGLATEKADHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MOAC_PSYIN
Sequence: MTHLFTHINQDGKANMVDVTDKNTTQRQAIAQAYVEMKAETLALILNGQHHKGDVFATARIAGIMAAKKTSDIIPLCHPLALTKVEVELVAEPEFNRVRIQSLCKLSGKTGVEMEALTAASVAALTIYDMCKAIQKDMVITQVKLLEKTGGKSGHFTSQ
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PGK_SHIFL
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOPB_YEREN
Sequence: MSALITHDRSTPVTGSLVPYIETPAPAPLQTQQVAGELKDKNGGVSSQGVQLPAPLAVVASQVTEGQQQEITKLLESVTRGTAGSQLISNYVSVLTNFTLASPDTFEIELGKLVSNLEEVRKDIKIADIQRLHEQNMKKIEENQEKIKETEENAKQVKKSGMASKIFGWLIAIASVVIGAIMVASGVGAVAGAMMIASGVIGMANMAVKQAAEDGLISQEAMQVLGPILTAIEVALTVVSTVMTFGGSALKCLADIGAKLGANTASLAAKGAEFSAKVAQISTGISNTVGSAVTKLGGSFGSLTMSHVIRTGSQATQVAVGVGSGITQTINNKKQADLQHNNADLALNKADMAALQSIIDRLKEELSHLSESHRQVMELIFQMINAKGDMLHNLAGRPHTV
What is the function of this protein?
Plays a role in virulence.
What are the official names of this protein?
Protein YopB.
What is the protein family that this protein belongs to?
To Shigella invasion plasmid IpaB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RT12_PETPA
Sequence: MPSLNQLIRHGREEKRRTDRTRALDQCPQKQGVCPRVSTRTPKKPNSAPRKIAKVRLSNRHDIFAHIPGEGHNLQEHSMVLIRGGRVKDSPGVKSHCIRGVKDLLGIPDRRRGRSKYGAEKPKSI
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SLMA_KLEP7
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLILGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVMREKKMREGEGYTLDETLLASQLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLVAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: POTA_STAA3
Sequence: MEPLLSLKSVSKSYDDLNILDDIDIDIESGYFYTLLGPSGCGKTTILKLIAGFEYPDSGEVIYQNKPIGNLPPNKRKVNTVFQDYALFPHLNVYDNIAFGLKLKKLSKTEIDQKVTEALKLVKLSGYEKRNINEMSGGQKQRVAIARAIVNEPEILLLDESLSALDLKLRTEMQYELRELQSRLGITFIFVTHDQEEALALSDFLFVLKDGKIQQFGTPTDIYDEPVNRFVADFIGESNIVEGRMVRDYVVNIYGQDFECVDMGIPENKKVEVVIRPEDISLIKAEEGLFKATVDSMLFRGVHYEICCIDNKGYEWVIQTTKKAEVGSEVGLYFDPEAIHIMVPGETEEEFDKRIESYEEVDNA
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MAGD2_HUMAN
Sequence: MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGACGFSYK
What is the function of this protein?
Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule.
What are the official names of this protein?
Melanoma-associated antigen D2, 11B6, Breast cancer-associated gene 1 protein, BCG-1, Hepatocellular carcinoma-associated protein JCL-1, MAGE-D2 antigen.
Protein: NUOH_FRAAA
Sequence: MSVTASTLVLAAPVDPDLSGFGDDPFWLILLKGVAVFAFLLLMTLFSIVFERKVVAKMQQRVGPNRHGPKGWLQSLADGAKLMLKEDLIPALADKPIFILAPILSAVPAFLAFAVIPFGPEVSIFGERTTLQLADLPVSVLYMLAAASLGVYGLILSGWSSGSTYPLLGSLRSAAQIISYEVAMGLSFVAVFIYAGTLSTSGIVESQSGRWYIALVPSFVLYCISMVGETNRTPFDLPEAEGELVGGFHTEYSSIKFAFFFLAEYINMVTVSAIATTLFLGGWQPPPIPGLSGLDHGWVPLIWFVLKLLLFLFFFIWLRGTLPRLRYDQFMAFGWKVLIPVGLLWVLVIATFRVYQKDVDDRTPWLIGAGVVIGIMLIVALLDPGGAKHQRELEEAERRKLAEAPSLESIPWPPPPPGGAHHRPAVPAGTSANGSSTVIPADPPPRQES
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZAPD_YERPY
Sequence: MSDLTSTILFEHPLNEKMRTWLRMEFLLQQLESHRSLDNIANALTFFRTASDLIDVLERGEVRTDLLKELERQQQKLQQWADIPGVDVSLVDSLRNQLKSRAAVLMSAPRIGQSLKEDRLISVVRQRLSIPGGCCSFDLPTLHVWLHQPSEQRDQHINKLLASLAPLHQSLTIILDLIRQSCPLRSQISLNGFFQDNAGGADLLRLRLPLDPQLYPQISGHKTRYAIRFLALDSENGTVPARLSFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: MWL1_ARATH
Sequence: MFIFLFGLAAFFLCLSAEFQKAKALLRAQVFLKGKDLKWDGESCYLPENRAFGLGIAALVCVSVAQIVGNVVICRGFTKTDKTRTTIFCIILLLFSWVNFAVAVTLISVGASMNREQIYGKGWLNRECYLVKDGVFAASGFLSVTTMAAILGAFAFKVKPSLQVENHDKRHTQNV
What is the function of this protein?
Together with MWL2, contributes to secondary cell wall biology, specifically lignin biosynthesis.
What are the official names of this protein?
Protein MODIFYING WALL LIGNIN-1, MWL-1.
What is the protein family that this protein belongs to?
Belongs to the DESIGUAL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBFA_STRA1
Sequence: MANHRIDRVGMEIKREVNEILRLRVNDPRVQDVTITDVQMLGDLSMAKVFYTIHSTLASDNQKAQIGLEKATGTIKRELGKNLTMYKIPDLQFVKDESIEYGNKIDEMLRNLDKKD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_ECOSM
Sequence: MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NBN_PONAB
Sequence: MWKLLPAAGPAGGEPYRLLTGVEYVVGRKNCAILIEKDQSISRNHAVLTANFSVTNLSQTDEIPVLALKDNSKYGTFVNEEKMQNGFSRTLKSGDSITFGVFESKFRIEYEPLVACSSCLDVSGKTALNQAILQLGGFTVNNWTEECTHLVMVSVKVTIKTICALICGRPIVKPEYFTEFLKAVQSKKQLPQIESFYPPLDEPSIGSKNVDLSGRQERKQIFKGKTFIFLNAKQHKKLSSAVVFGGGEARLITEENEEEHNFFLAPGTCVVDTGITNSQTLIPDCQKKWIQSIMDMLQRQGLRPIPEAEIGLAVIFMTTKNYCDPQGHPSTGLKTTTPGPSLSQGLSVDEKLMPSAPVNTTTYVADTESEQADTWDLSERPKEIKVSKMEQKFRMLSQDAPTVKESCKTSSNNNSMVSNTLAKMRIPNYQLSPTKLPSINKSKDRASQQQQTNSIRNYFQPSTKKRERDEENQEMSSCKSARIEMSCSLLEQTQPAIPLLWKNKEQHLSENEPVDTNSDNNLFTDTDLISTVKNSASKSHAAEKLRSNKKREMHDVTIEDEVLEQLLKDTKPELEIEVKVQKQEEDVNIRKRPRMDVETNDTFSDKAVPESSKISQENEIGKKHELKEESLWSTKEISNNDKLQDHSEMLPKKLLLTEFRSLVIKNSTSRNPSGINGDYGLLKNFKKFKKVTYPGAGKLPHIIGGSDLIAHHARKNTELEEWLRQEMEVQNQHAKEESLADDLFRYNPYLKRRR
What is the function of this protein?
Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity.  The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.  The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11.  RAD50 may be required to bind DNA ends and hold them in close proximity.  NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions.  It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX.  NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation.  NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints.  The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability.  Forms a complex with RBBP8 to link DNA double-strand break sensing to resection.  Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex (By similarity).
What are the official names of this protein?
Nibrin, Nijmegen breakage syndrome protein 1 homolog.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Chromosome, telomere. Chromosome. Note=Localizes to discrete nuclear foci after treatment with genotoxic agents. Acetylation of 'Lys-5' of histone H2AX (H2AXK5ac) promotes NBN/NBS1 assembly at the sites of DNA damage.
Protein: OBG_SHESR
Sequence: MKFVDEAVIRVEAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLQADENHNTLIEYRFERFHMAERGENGRGRDCTGHSGKDLILKVPVGTRAIDDETEEVLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELLLLADVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRILLHIIDIEPIDGTDPVDSARAIVGELEKYSPKLASKPRWLVFNKADLLLEDELKEKVARVVKELGWEGDVYTISAYSRDGTKELATKLLDFIQSLPPEDKDANPDAEVEFKWDNYHQANIDAINEDYDDEFDDDFDDDDYDVEVIYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_RHOBA
Sequence: MQNFTVHQGVVATLDRANVDTDQIIPKQFLKRIERTGFGQFLFFDWRFLEDGETENPDFELNRINVKGASILLTRQNFGSGSSREHAVWALDDYGFRAVIAPSFADIFFNNCFKNGVLPIALSEEDVEELFQRAEKGNPYQLTVDLENQVITDGQGFERSFEVDASRRHNMLHGLDDIAQTLLHEDKITAFEEARG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.