PharMolix/UniProtQA huggingface dataset:
Protein: RECF_XANC8
Sequence: MHVARLSIHRLRRFEAVEFHPASTLNLLTGDNGAGKTSVLEALHVMAYGRSFRGRVRDGLIRQGGQDLEIFVEWRERAGDSTERTRRAGLRHSGQEWTGRLDGEDVAQLGSLCAALAVVTFEPGSHVLISGGGEPRRRFLDWGLFHVEPDFLALWRRYARALKQRNALLKQGAQPQMLDAWDHELAESGETLTSRRLQYLERLQERLVPVATAIAPSLGLSALTFAPGWRRHEVSLADALLLARERDRQNGYTSQGPHRADWAPLFDALPGKDALSRGQAKLTALACLLAQAEDFAHERGEWPIMALDDLGSELDRHHQARVIQRLASAPAQVLITATELPPGLADAGKTLRRFHVEHGQLVPTTAAD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPHAA_HUMAN
Sequence: METCAGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQLQGQGVQV
What is the function of this protein?
Receptor for members of the ephrin-A family.  Binds to EFNA3, EFNA4 and EFNA5.
What are the official names of this protein?
Ephrin type-A receptor 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: YSYM_RHIET
Sequence: MLCLGLSGRLSRVYENSFDLPNSFMHNGAAVRVRDGRVIAAVEEERPNRIKHSNTLPIRSIQYCLASAGVQLSDIDRIAYYATEAYCNAVLERVRLSHPSTPVSDARLLQRARGGRHGLYIPVGHPDVPCDRHRHTDLAAHWTRDGTMPWRLSPALHRRDELENVGPGIDC
What are the official names of this protein?
Uncharacterized 19.2 kDa protein in syrM 5'region, ORF2.
Protein: PHEA2_HEMVI
Sequence: MYTKAVLLAFVGSAAAFNAPMMTVRRDAIATGAAAAVVAPLLRPAGAKMATDSKAPLIELFDERDGCKGPAANKASDVGEPGLCVKVSMQKVAMNAAAAKSVATNYMRK
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
Phycoerythrin alpha-2 subunit.
What is the protein family that this protein belongs to?
Belongs to the phycoerythrin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: DOK7_HUMAN
Sequence: MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDKSERIKGLRERSSLTLEDICGLEPGLPYEGLVHTLAIVCLSQAIMLGFDSHEAMCAWDARIRYALGEVHRFHVTVAPGTKLESGPATLHLCNDVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGGTRCGYWAGVFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPGEPWEAGGPHAGPPPAFFSACPVCGGLKVNPPP
What is the function of this protein?
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis.  Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes.  Induces autophosphorylation of MUSK.
What are the official names of this protein?
Protein Dok-7, Downstream of tyrosine kinase 7.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Synapse. Note=Accumulates at neuromuscular junctions.
Protein: PEPVL_STAAW
Sequence: MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLAEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFDSDFGEKMGMKFHTDVMGDVTNNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
What are the official names of this protein?
Putative dipeptidase MW1694.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: RR3_CHLRE
Sequence: MGQKVHPLGFRVGITKKHQSQWFARFQKYAYSQSVFEDHMLRTTLVNLFSNLEKESALATKQSKNRGATQPKAPKITQIKIERGLIPYEIGIQIHSNDCLSITKAIDNIKVSKDLVTNLQKTRKYLFKAGTQLKNASMQVSDNLNVAEGENSTMLKTKTSASGTSVLKKRTFKIQTQKPTKGKFVFKGKRKQKKKLSKAVFMRLKNIKRRFKKRQTIKKRYLNIISKGLLIRKKGNLIIRNVKIKRKNKTARLTSRKSQPTLRSGSNLRDNLAPVKSKMQRFNNRMSKKFANLFLTKLNKQFLVRLKAIMKFWHNQNVTKAPLGYNKKWSLAKSYALINNLKAKYLAKDILSLGSLRVQKLRKLISILEKKSLVKMETLRKDFITFGTLSKTRAFGYYQMITFLKQLKELVTKIKKQTIANVTTKQELCCYNKLALNKTKIQNLIRAKSKQTKSITQKVVNNFVKLVDDNQAMANESRKIKWISYLKDLVNKHRTENIFYYLATIATARKDLNALKRYTKQHANFLFGVNVENAKENPNALLQRVTKTLTQYSKNPLVNNDFENAEGLTKLQTAFLTQIESQRKMYKANLALTPKISIKFFSVKTTNLLEKASTVADSIVDALEKRKAFRGVIKKAKEDLMLRSRVTRVKGVKIQVAGRLNGAEIARSEWVRAGRVPLQTLRANIDYAYRTANTIYGIIGVKVWIFKGYSKI
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic, ORF 712.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RP35_FOWPN
Sequence: MHRQEYRIDVSANPSIATFIKHMCKKHLVIPRLNVGVVMINTTTAINEEWLTSIESLPTHKIFYDYVYDIIAMQCNFCIHLKKTQKENDSYISLADIDYYIIKPEEVIKLDPIKELKETLLHSFSEYRATNTKTIELAAFSSGTKINDELVNRLSFLDTELFNREYKNVKIIHSQNYETYFPFSIIAPEGNISIFMEKYTWFNSSVYFKSMLSYLKEVISDQIAEFNITKLDMEKDTPTSSAYDPKSNIVFVNDITTMCIINFFGCECQLGTYHKFNISSINTKTFHKAVNKTISEIYKAIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase 35 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 35 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: KDSB_RICBR
Sequence: MKHQDVAIIIPSRLSSTRLTRKPLQLIGSSTLIERVFKQVNQTNLEHIYVATDSQEIASVIEKLGGKVIFTDSNIPTGTDRTYEAFKLIPNNQNINYIVNVQGDMPFIEPESILKVIEDLKNSKYDIVTPVVKVEKDSVEAASNVTVAIDSKGKAIYFSRSLIPNGAEEFLYHVGMYGFRKSALERFVALEPTFLEKTERLEQLRLLENGMTIGTCLVNNVPISVDTPEDLSKAVKFYEKSKLV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_HORVU
Sequence: MTRKKTNPFVAHHLLAKIEKVNMKEEKETIVTWSRASSILPTMVGHTIAIHNGKEHIPIYITNPMVGRKLGEFVPTRHFTSYENARKDTKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARGB_RHOJR
Sequence: MTAISEALSGITDHQKAHVLAEALPWLQQFRDKVVVVKYGGNAMVDDALKTAFAADMAFLRTVGIQPVVVHGGGPQINAMLGKLGMTGEFKGGFRVTTPEVMDVVRMVLFGQVGRELVGLINAHGPYAVGISGEDAHLFTATKRTVMVEGKPTDIGLVGDVTTVNPEAVLDLIRAGRIPVVSTIAPDSDGVVHNINADTAAAALAEAIGAEKLVVLTDVEGLYTNWPDRDSLATEIDVDALAQLLPSLDAGMVPKMEACLRAVRGGVPTAHVIDGRVAHSVLLELFTGEGIGTMVTPGPTSPTEGVAS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWAHB_HUMAN
Sequence: MARELSQEALLDFLCQAGGRVTNAALLSHFKSFLRDPDASPSQHQHRRELFKGFVNSVAAVRQDPDGTKYVVLKRRYRDLLGEEGLQRPREPPAAAPSAGGAAPCSPRGARRGEPPQQQPRRRRREKEPEEEPAGAAARAADAACNGLPGSDSRRAPGKGGGSKGSPGQRPPVPAAAAAGAQARASCAAAKTQGRCCWECLQNNLAVLPGELGALPHSATAEEKPARALPAQDDRGASREREEGALAEPAPVPAVAHSPPATVEAATSRASPPALLPGPAPRGDRPELLTPSSLHYSTLQQQQQRTREWVARHPQVPEARDQGPIRAWSVLPDNFLQLPLEPGSTEPNSEPPDPCLSSHSLFPVVPDESWESWAGNPSLTVFRSIRCQLSLQDLDDFVDQESDGSEESSSGPKDSPGASEEGLQVVLGTPDRGKLRNPAGGLSVSRKEGSPSRSPQGLRNRGDGHISQQVPAGANGLAGHPLKPLPWPVPKLRRSLRRSSLAGRAKLSSSDEEYLDEGLLKRSRRPPRSRKPSKAGTAPSPRVDAGLSLKLAEVKAVVAERGWRHSLWVPSGEGSAALAPHRTSEHKSSLVPLDAREHEWIVKLASGSWIQVWTLFWEDPQLALHKDFLTGYTALHWIAKHGDLRALQDLVSGAKKAGIVLDVNVRSSCGYTPLHLAAIHGHQGVIKLLVQRLASRVNVRDSSGKKPWQYLTSNTSGEIWQLLGAPRGKPIFPVYPLVGSSSPTRKAKSKEISRSVTRKTSFAALLKSQHNKWKLANQYEKFHSPREREEYSD
What are the official names of this protein?
Ankyrin repeat domain-containing protein SOWAHB, Ankyrin repeat domain-containing protein 56, Protein sosondowah homolog B.
What is the protein family that this protein belongs to?
Belongs to the SOWAH family.
Protein: CH60_AGRVS
Sequence: MAAKEIKFGRTAREKMLHGVDILADAVKVTLGPKGRNVIIDKSFGAPRITKDGVSVAKEIELEDKFENMGAQMVREVASKTNDIAGDGTTTATVLAQAIVREGNKAVAAGMNPMDLKRGIDLAVAEVVKDLQAKAKKISTSEEVAQVGTISANGDTQVGKDIAEAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNPEKMVADLEDAYVLLHEKKLSNLQAMLPVLEAVVQTGKPLVIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGTVISEDLGIKLETVTLDMLGRAKKISITKENTTIVDGAGQKSDIEGRVAQIKAQIEETSSDYDREKLQERLAKLAGGVAVIRVGGSTEIEVKERKDRIDDALNATRAAVQEGIVPGGGTALLRSSTKITVKGVNDDQEAGINIVRRALQSLVRQIATNAGDEASIIVGKILDKDNDNYGYNAQTGEFGDMIAMGIVDPVKVVRTALQNAASVASLLITTEAMIAELPKKDSAGGGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK14_PIPCE
Sequence: MIQTQTYLNVADNSGARELMCIRILGASNRRYANIGDIIVAVIKEAVPNMPLERSEVIRAVIVRTCKELKRDNGMIIRYDDNAAVVIDQEGNPKGTRVFGAIARELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS19_ALKMQ
Sequence: MSRSAKKGPFIHKGLLRKIEEMNEKDEKKVIKVWSRASTIFPQMIGHTIAVHDGRKHVPVYVTEDMVGHKLGEFALTRTYRGHDDDEKTSKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GLGA_BORPA
Sequence: MTTIRTLVVAAEAFPLAKTGGLGDAVSGMVQALGHRPGGVDVQCELLMPAYRGTLDMVYRPRTVARLGGLPGGPASLVRGHCPGSGLSVLLLRNDALYDRPGIYVDDSGQGYPDNARRYAALAHAAARLAQGLPGLRPPHVVHAHDWHAALAPLLIHAAGLHYVKTLLTIHNLAFQGTFPAELASALGIPLACRHDDGALSDDSVNFLKAGIRYATRVTTVSRAYAREILTPAFGCGLHGLLRARGADLSPVPNGIDTALWNPAADPHLGGLRFDALDMRNKACCKAALQAELGLQPRADATVLAMGSRLTGQKMADVAIAALPALLEAHEHLQFALIGRGEPALETALRALAARYPGRCAVHIGYDEPLAHRLHAGADLLLHGSRFEPFGLTPLYAMRYGTLPVASRVGGMVDTIRDPGPAVEESCAGQGTGFLFDGSEPADMQLAVARALRALAKPAVCDAMRRNAMQADFSWRASAQAYAGLYASLASAPQRGRVPAPTLPLLANAA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: FMDC_METWO
Sequence: MGFVLVPKSDFQIPLEADTIDPICLKGWDLDEIRSLQVYEGNIKRPLGEFFEIAETSHEDQLIRIDGDVSRVKYIGSGMKSGKIIINGDVGLQLGCEMKGGEIEVNGNVSSWIGMEMHGGTIKINGNAGDYVGCAYRGEWRGMKGGKIIIQGNAGNNIGGGMMAGEIYIGGDAGNFCGIRMNGGEITVRGDAGRAPGAEMVSGIIKIHGRISSLLPGFKEISTFKEDGSLMILFKGDLSEKNPEGNLYINYNKNLHILENETDEGRVITKKGIKVIYNSGSTIREGQIIKGGNKLTDDYIDECARCCISPEDYKLLGEPENVVVSSHGNEVVLRAVEDPGIQMGTIFIPRGIWANVLTPPYTESTGSPMYKGVPVYLRKASQGERILSAEELVEEYGVGK
What is the function of this protein?
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR).  Can only oxidize formylmethanofuran.  This enzyme is oxygen-labile.
What are the official names of this protein?
Molybdenum-containing formylmethanofuran dehydrogenase 1 subunit C, Molybdenum-containing formylmethanofuran dehydrogenase I subunit C.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the molybdenum dinucleotide binding protein family.
Protein: ENO_BURPS
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYGGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILGDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHEGDWDGWKLLTERLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRARYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ADA2B_MOUSE
Sequence: MSGPAMVHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPHGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPHPAAGGVPASAKVPTLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPNWSALPRSVQDQKKGTSGATAEKGAEEDEEEVEECEPQTLPASPASVFNPPLQQPQTSRVLATLRGQVLLSKNVGVASGQWWRRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRQWTQTGW
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Alpha-2B adrenergic receptor, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor, Alpha-2BAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Interaction with RAB26, GGA1, GGA2 and GGA3 mediates transport from the Golgi to the cell membrane.
Protein: RF3_PROMH
Sequence: MANQDFLNEINKRRTFAIISHPDAGKTTITEKVLLFGQAIQRAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYADCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDSSKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELMDEVETELKIACSPVTWPIGCGKLFKGVYHILRDETYLYQTGQGHTIQNSRVIKGLDNPELDEAIGDDLAVQLRDELELVLGASHEFDHEAFLAGELTPVFFGTALGNFGVNHMLDGLVKWAPAPMPRQTDMREVTAAEETFTGFVFKIQANMDPKHRDRVAFLRVVSGMYDKGMKLHQVRTKKDVVISDALTFMAGDRSHVEHAYPGDIIGLHNHGTIQIGDTFTQGEMLKFTGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLANNDLIVGAVGVLQFDVVVARLKGEYNVEAIYESVNVSTARWVECSNEKKLEEFKRKNEQHLALDGGDNLTYIAPTMVNLNLTRERYPDIEFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMAT4_ARATH
Sequence: MFRKRNLVLDLLRRCYIETLIPRGLWSRTISTFPKSALLATDNAEMASKETGMFSLAGELASLVEESSSHVDDDSKPRSRMELKRSLELRLKKRVKEQCINGKFSDLLKKVIARPETLRDAYDCIRLNSNVSITERNGSVAFDSIAEELSSGVFDVASNTFSIVARDKTKEVLVLPSVALKVVQEAIRIVLEVVFSPHFSKISHSCRSGRGRASALKYINNNISRSDWCFTLSLNKKLDVSVFENLLSVMEEKVEDSSLSILLRSMFEARVLNLEFGGFPKGHGLPQEGVLSRVLMNIYLDRFDHEFYRISMRHEALGLDSKTDEDSPGSKLRSWFRRQAGEQGLKSTTEQDVALRVYCCRFMDEIYFSVSGPKKVASDIRSEAIGFLRNSLHLDITDETDPSPCEATSGLRVLGTLVRKNVRESPTVKAVHKLKEKVRLFALQKEEAWTLGTVRIGKKWLGHGLKKVKESEIKGLADSNSTLSQISCHRKAGMETDHWYKILLRIWMEDVLRTSADRSEEFVLSKHVVEPTVPQELRDAFYKFQNAAAAYVSSETANLEALLPCPQSHDRPVFFGDVVAPTNAIGRRLYRYGLITAKGYARSNSMLILLDTAQIIDWYSGLVRRWVIWYEGCSNFDEIKALIDNQIRMSCIRTLAAKYRIHENEIEKRLDLELSTIPSAEDIEQEIQHEKLDSPAFDRDEHLTYGLSNSGLCLLSLARLVSESRPCNCFVIGCSMAAPAVYTLHAMERQKFPGWKTGFSVCIPSSLNGRRIGLCKQHLKDLYIGQISLQAVDFGAWR
What is the function of this protein?
Nuclear-encoded maturase required for splicing of group-II introns in mitochondria.  Involved in NAD1 pre-mRNA processing and maturation of introns 1, 3 and 4.  Necessary for mitochondrial biogenesis during early developmental stages.  Essential for respiratory holocomplex I biogenesis in mitochondria.
What are the official names of this protein?
Nuclear intron maturase 4, mitochondrial, AtnMat4, Nuclear intron maturase 2 b, AtnMat2b.
What is the protein family that this protein belongs to?
Belongs to the plant nuclear intron maturase (nMat) family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Plastid, chloroplast.
Protein: NCKX2_MOUSE
Sequence: MDLHQSPTARLLQKWCSHESPFGCRRHYNSRKKLKLIRVIGLVMGLVAVSTVPFSISAFTETDSQSNRGEASDMSGPRVAQGHRQRTLLDLNDKIRDYTPQPPASQEDQAENSTEHTQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPLFRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVVFMKFNVQVERWVKQMISRNNVIKVTVPEAQAKSPTAGDKDGPTLPSKPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAKKKCQVDENERQNGAANHVEKIELPNSTSTEVEMTPSSEASEPVQNGNLSHNIEAADAPKATETAEEEDDQPLSLSWPTNTRKQATFLIVFPIVFPLWITLPDVRKPASRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTIIHRFSPVTVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDKVLVCPVSI
What is the function of this protein?
Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (By similarity).  Required for learming and memory by regulating neuronal Ca(2+), which is essential for the development of synaptic plasticity (PubMed:16407245).
What are the official names of this protein?
Sodium/potassium/calcium exchanger 2, Na(+)/K(+)/Ca(2+)-exchange protein 2, Retinal cone Na-Ca+K exchanger, Solute carrier family 24 member 2.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADA_BURO1
Sequence: MQSTIKPVEYDRPVAAGTVCGVGQAWAKVPDAPSAEERAALKARIKALLAREKAVLVAHYYVDAELQELADETGGCVADSLEMARFGRDHDAQTLIVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGSYIQKKTGADMLLWQGSCLVHDEFKGIELDLLRAEYPDAKVLVHPESPENVVAQADVVGSTTQLIDAAVKFDAKRFIVATDLGILHKMQLAAPGKTFIAAPTAGNSATCKSCAHCPWMAMNGLANLADVLERGHNEIFVDPAIGERARLPIDRMLEFAAAHKKRVQASGDLQRDQSLFANVGAA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
Protein: HLDE_ECOBW
Sequence: MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVNTIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMKLIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANGGEVLVLNFEDGCSTTNIIKKIQQDKKG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: E321_ADE07
Sequence: MISTTIFIISSLAAVTYGRSHLTVPVGSTCTLQGPQQGYVTWWRIYDNGGFARPCDQPGTKFSCNGRDLTIINITSNEQGFYYGTNYKDSLDYNIIVVPATTSAPRKTTFSSSSAKASTIPKTASAMLKLQKIALSNSTAAPKTIPKSTIGIITAVVVGLIIIFLCIMYYACCYRKHEQKGDALLNFDI
What is the function of this protein?
E3 proteins seem to be dispensable for virus growth in tissue culture cells.  They are potentially important for virus growth under special conditions; E3 region may help adenoviruses to evade the immune surveillance of the host.
What are the official names of this protein?
Early E3 20.5 kDa glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3_20 family.