PharMolix/UniProtQA huggingface dataset:
Protein: STYL2_DANRE
Sequence: MASSVEDQQLQQEEAESVKDVQSHYLRCPSPSFSMMSDRFSTVSDRFSVISGSEAESIFMEPIHLSSTIAAKKIISEELPPRPARVSSPPDSALEPAQQLMVEDLYSRVQELLDERSLYNTPCVLDIQRALLRDRLEAPLSPVDEVWPNVFIAEKSVAVNKGRLKRLGITHVLNAAHGTGVYTGPLFYSGMNIHYMGIEVDDFPDADISPHFRSCAEFLDDALLTHRGKVLVDSMMGVSRSAVLVAAYLMIFQNMSIMEALLEIRKKRAISPNEGFIKQLRQLNETLMEERDEDDDETLSQCSVIDARGRLEEQESVFGVKADSIMVEEEEDGGGSVISSVASSAAAAALRAGVQCGSQQPNMQQPADQPSLPGQTREDEDGDVDRMILEWQKRNEKYQSEDWWEAQLLCEDEDDGEDKTQRAVRPDDLESVTSEDVRMVKERIGRRPRRAASLAGSTSSCSSYVDLWKQRLQELEEQAAARHRLQDQDTSSETQQKKIDDDVQSILSDSSSMYNFCKKNKENLTPLERWKIKRIQFGWNKKENAENGEQSEAEPAAAPDLEDVNLTAYQTWKLKQQKKHGGEENKEEILQMSRGEDTATARRRQRREEVLERSRRNLQESQSVCGWETESALSSSIPLSAFCAGAFPSASVCGDDSMSVLSGRSSVLSGRSTRSLPPAVLETPAPPTPVLGPNGEQMVNIANIQNWIASVVNETLQQKQTEMLMGASVAPSRAGSVFSAGRGVDDDKSSVLSGLSASTGLSRSRAESVVSVGAKARSVLSAAGRAESVFSAGGASQLSCGSRKSKITTTSVPLYSLFQDQVNLHKLDTMEKEIKSDMRDKMASYEIKKITEDNKRSTLYKKKKPKEDDEDVDIAKSNGLEELEARTCEKPKPKRDYGRSGILNLPASANNPTSSIDEWLEHVRPPSSKPRVYDGDSGPIRMSRPAYEELQEPSGLDFTSRRSSVSVEVDEEEDYSFRFSSRNCADDDLDPELSYSSRRSPSFNGLSESTSFASRRSYSRYEDEERSSFQNHSIKQKSSVYEDSGRTAGSRRDEEEDEEISAFIAQIKQRARARVAEEMEDDEVLTAWRKQEESKSHDHK
What is the function of this protein?
Required for myofiber maturation.
What are the official names of this protein?
Serine/threonine/tyrosine-interacting-like protein 2, Inactive dual specificity phosphatase 27.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere.
Protein: KAPC_ENCCU
Sequence: MLKIQDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRIYGCPFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFIHGRGILYRDLKPENILITSTGHIKLIDFGFSVYESENIYMISGTPEYMSPEKLRSEDDGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYVSPVARCLITGLLDKNRATRLGTKGICEIMGHPFFKGIDWHEVESRRIEPPFIPNPNTVLSSLASSGELKGTDDAETVVLKPYKHIKHLYKVSKGL
What are the official names of this protein?
Probable cAMP-dependent protein kinase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein: RL19_YERPS
Sequence: MSNIIKQIEQEQMKQDVPAFRPGDSVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVIDSITVKRRGAVRQAKLYYLRERTGKSARIKERLG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ACKA_SYMTH
Sequence: MKILVLNCGSSSIKYQLLDMETESVLAIGKVERVGMEDAIFEYKGAGEKIKEIGTILDHTAGVRKVLKALTDPVHGVIQAPEEIAAVGHRVVHGGEAFVKSVIITDEVKRTLRELFDLAPLHNPANLTGILAAEAALPHAPGVAVFDTAFHATMPRKAFLYALPYAMYKGHKVRRYGFHGTSHKYVSQRAADLLGRPLEEVNLITCHLGNGSSVTAVQGGKSVDTSMGFTPLAGLIMGTRAGDLDPGVIPYIMAREEIGISEVNSMLNKHSGILGISGISSDMRQIEEEMEKGDPRAVETFEMMEYRLRKYIGAYAAVLGRVDGIVFTGGIGENSPLFRKAVCQNLGFLGVTFDEEANNCRGQERIISGPDSKVAVMVIPTNEELMIARETAELIRNR
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_STRA1
Sequence: MKLKIITVGKLKEKYLKEGVAEYQKRLNRFSKIETIELADEKTPDKASISENQRILDIEGERILSKIGERDYVIGLAIEGKQLPSESFSHLIDQKMISGYSTITFVIGGSLGLSQKVKKRADYLMSFGLLTLPHQLMKLVLMEQIYRAFMIRQGTPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_STRMK
Sequence: MKIYLVGGAVRDRLLQRPAGDHDWVVVGATPAQMEAQGYTAVGRDFPVFLHPKTGEEYALARTERKSGRGYRGFVVDADPGVTLEEDLQRRDFTINAIACDEETGTLVDPYGGVRDIEQRVLRHVGPAFVEDPLRVLRAARFMARFAPLGFTVAEETMALMREIAASGELDALVPERVWQELRKALVSERPSAFLRTLHDAHALGPILPELEALYGVPQRAEFHPEVDTGIHQEMVSDMAAKLAPGDDLVGFAALTHDLGKGLTPPEEWPRHIMHEQRGIKPLKALCARLKIPAEHQQLAEAVCREHLNVHRIDELRDATVLELLGRCDALRRPERVARIALCCEADKRGRLGFEDADYPQGETLKRLHQAALSVQARDLDTTHLKGPAIGEALAKARVKAIAAAR
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: MUKB_YERPA
Sequence: MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLRAGVCYSTLDVVNSRHQRVVVGVRLQQVAGRDRKVDIKPFTIQGLPTAIQPTEILTELVAERQARVLSLPELKERVEAMEGVQFKQFNSITDYHSLMFDLGVIPKRLRSSADRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATSYVAADYMRHANERRIHLDSALVLRRDLFSSRKQLVTEQYRHVEMSRELAEQSGAESDLETDYQAASDHLNLVQTAMRQQEKIERYQSDLEELTYRLEEQSEVVSEASEQQADNEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYQQALQALERARALCQLPELTADNAEEWLETFHAKEQEATESLLQLEQKLSVADAAHSQFEQAYQLVVNIAGEVSRSEAWQTARELLRDWPSQQHLAERVQPLRMRLSELEQRLRAQQDAERLLQEFCKRQGNAYQPEELEALQRELESQVEELSLSVSDAGERRMAMRQELEQLKLKIQELTARAPVWLAAQDALSQLSEQSGEALEDSRQVTEYMQQLLERERETTVERDEIAASKRAIEAQIERLSQPSGAEDARLIALAERFGGVLLSEIYDDVTIDDAPYFSALYGPSRHGIVVPDLSLVREHLQGLDDCPEDLYLIEGDPQSFDDSVFAVEEHEKAVVVKIADRQWRYSRYPEVPLFGRAARENRLETLYQERDRLAERYATLSFDVQKTQRTHQAFSRFIGSHLAVAFDADPEAEIRLLNTRRGEIERALNAHEDQNQQQRQQFDQAKEGISALNRLIPLVSLLLDETLTDRVEEITEELAEAQEAARYIQQHGVSLTKLEPLLSVLQSDPQQHEQLQESYVLAQNSQRLAKQQAFALTEVVQRRAHFSYTDSAGMLTENSDLNDKLRQRLEQAEAERTRAREQLRQYQSQFTQYSQVLASLKSSYDAKRDMLKELSQELVDIGVPADANAEARARARRDELHAALSTNRSRRNQLEKQLTFCEAEMDSLQKKLRKLERDYHQIREQVVNAKAGWCAVMRMVKDNGVERRLHRRELAYMDGDELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFYIAVYQHLRERIRQDIIRTDDPVEAIEQMEIELGRLTEELTAREQKLAISSKSVSNIIRKTIHREQNRIRMLNQGLQAVSFGQVKSVRLNVNVREAHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQMDMGQRLPQTIGEELLDYRNYLELEVEVYRGADGWLRAESGALSTGEAIGTGMSILVMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCERLEMQLIIAAPENISPEKGTTYKLVRKVFQNHEHVHVVGLRGFANEMPSLPPIAAELQQGG
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RRP4_PYRAE
Sequence: MYYVTPRQLVFPGDVIATADSKVEGPVYLDNGKYRSLVVGLVEFREDVVVVVPLEGTYKPKKGDLVIGYVTDVLATGWEVDVRSFMPAYLPVGEALHRHVDLETTPLTTFLNIGDVVVAKVKDVDLTDEYPIILTLKDEKVGKVESGTVVEITPVKVPRVIGKRGSMLNTLMELGCDIVVGQNGRIWVKCKDPRDEVFLASLIRKIEAESHVMGLTDRIRAEIENYKTSKQQGTV
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Increases the RNA binding and the efficiency of RNA degradation.  Confers strong poly(A) specificity to the exosome.
What are the official names of this protein?
Exosome complex component Rrp4.
What is the protein family that this protein belongs to?
Belongs to the RRP4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_ECOLI
Sequence: MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVKARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQKLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPASIAGCKKVVLCSPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPAADMARRVAEAVERQLAELPRAETARQALNASRLIVTKDLAQCVEISNQYGPEHLIIQTRNARELVDSITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: YHAM_SHIBS
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNSVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: MSBA_AROAE
Sequence: MHRSDAAPASSIRIYFRLLSYVRPYVGLFAVSILGYVIFASSQPMLAGVLKYFVDGLTHPDAALVTGVPLLDGMELMHGVPLMIVLIAAWQGLGGYLGNYFLARVSLGLVHDLRQTLFDSLLRLPNTYFDQHSSGHLISRITFNVTMVTGAATDAIKIVIREGLTVVFLFAYLLWMNWRLTLVMVAILPLISLMVRNASGKFRKQSRKIQVAMGDVTHVASETIQGYRVVRSFGGEHYERERFRAASEDNTRKQLKMVKTSAVYTPTLQLVTYSAMAVVLFLVLRLRGEASVGDLVAYITAAGLLPKPIRQLSEVSSTIQRGVAGAESIFEQLDDKPEVDHGRIERERVSGRIEVRDLSFRYPGSDREVLDSVSFTVEPGQMIALVGRSGSGKSTLANLIPRFYHHDRGQILIDGVDVEDYTLKNLRRHIALVTQQVTLFNDTVANNIAYGDLAGLPRAAVEAAAEAGYAKEFIDRLPQGFDTLIGENGVTLSGGQRQRLAIARALLKNAPILILDEATSALDTESERHIQAALHRVMQARTTLVIAHRLSTIEQADVIMVMDHGRIVERGSHAELLAAGGHYARLHAMQFREEPAVAEGR
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BCCP1_ARATH
Sequence: MASSSFSVTSPAAAASVYAVTQTSSHFPIQNRSRRVSFRLSAKPKLRFLSKPSRSSYPVVKAQSNKVSTGASSNAAKVDGPSSAEGKEKNSLKESSASSPELATEESISEFLTQVTTLVKLVDSRDIVELQLKQLDCELVIRKKEALPQPQAPASYVMMQQPNQPSYAQQMAPPAAPAAAAPAPSTPASLPPPSPPTPAKSSLPTVKSPMAGTFYRSPAPGEPPFIKVGDKVQKGQVLCIVEAMKLMNEIESDHTGTVVDIVAEDGKPVSLDTPLFVVQP
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxyl carrier protein of acetyl-CoA carboxylase 1, chloroplastic, AtBCCP1, BCCP-1.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL10_BUCAP
Sequence: MALNLSKKKTIVSKINQISNLALSAIIANSQGISVNKINELRKSGREIGVKMSIVRNTLLSLAIENTAFKCLKKKLKGSTFIAYSTKHPGSGARLFKEFEKKNKKFKITGAVFEGKLLSELEINQLADMPTYEEAIRKLLLTLKISIAGKLIYTLSAIKEKKETS
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: TRMB_MYCBO
Sequence: MVHHGQMHAQPGVGLRPDTPVASGQLPSTSIRSRRSGISKAQRETWERLWPELGLLALPQSPRGTPVDTRAWFGRDAPVVLEIGSGSGTSTLAMAKAEPHVDVIAVDVYRRGLAQLLCAIDKVGSDGINIRLILGNAVDVLQHLIAPDSLCGVRVFFPDPWPKARHHKRRLLQPATMALIADRLVPSGVLHAATDHPGYAEHIAAAGDAEPRLVRVDPDTELLPISVVRPATKYERKAQLGGGAVIELLWKKHGCSERDLKIR
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RF1_LARHH
Sequence: MKPSILTKLAQLSDRLDEVTGLLGDPDVTRDMDAYRRLTREHAELTPVVEQYLAWRQTEADLASARDLLDDPDMKELAEAELSDGQERLAVLELELQKLLLPKDPNDERNIFLEVRAGTGGDEAALFAADLFRMYSRYAERNRWQVEIVSASENDLGGFKEVIARIVGFGAYSRLKFESGGHRVQRVPATETQGRIHTSACTVAVMPEADELAAVELNPADLRIDTFRASGAGGQHINKTDSAVRVTHLPTGIVVECQDDRSQHKNKARALAVLAARIQDVQQRARQQKEAAERKSLIGSGDRSERIRTYNFPQGRVTDHRINLTLYRLDAVMDGDLAELTDALTAEHQAELLAQLAGD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_SULTO
Sequence: MPQTLTEKILSRASGKSVAPGDVVEVKVDIAAFHDLTGYHVIEVMEKAGMLKVFDKQKIVIAFDHLAPPPDVRSAEIQTQIRKFVKELKIPNFHDINVGILHQILLEKYANPGYVIVAADSHTTTSGAVGAFAQGLGASDVAAAVITGKTWVMVPQSFKIMLEGKPGKWINGKDVALKILGDFKADYFNGMSIEIFVREPSAFPMDFRATVSNMGIEMNADALMFVPDEETVNYIKTNRGYEPNIVRPDEGAKYVDEYTIDLGKLEPLVAAPHSVDNVKTVNEVEGLDVDQVFIGSCTNGRISDFEIAAKILKGKRVKSRCIAIPASYDLFKKAMELGYIETLVNAGCIVTYGTCGPCLGGHFGVAGPGETIVSTSSRNFKGRMGSNDSKVYLAGPAVAAASALQGKITDPRRFS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: FAA29_MYCMM
Sequence: MIMDTNAVSFRARDEVTTQLAPGTGGQAVPTSNGMMTRFAMSESSLTDLLHKAATQYPNRAAYKFIDYDVNPDGFTETLTWWQIYRRAKIVAEELRGYGASGDRVAVLAPQGLEYIIAFLGVLEAGLIAVPLPVPQFGIHDERISAALQDSTPSVILTTSPVIDEVTKYAPHARAGQGGTPIVVAVDLLDLDSARELDLTPPAHSSTAYLQYTSGSTRSPAGVVLSHKNVITNCVQLMSDYLGETEKVPSTAVSWLPFYHDMGLMLGIILPMINQDTAVLLNPMAFLQRPARWMQLMGKFRGQISCAPNFGFELAVRRTSDEDMAGLDLGHVRGIGSGAERVNPATLQRFIDRFAPFNLRDTAIRPSYGLAEATVFVATAEPGRPPRSVNFDYQSLSVGRVERCANEADDGAKLVSYGSSWTSEVRIVDPEARTECPAGTVGEIWVQGDNVAMGYWRNPQLTERTFDAKLTDPSPGTSIGPWLRTGDLGVMFEGELFITGRIKDLLIVDGSNHYPDDIESTIQEITGGRVVAIAVPDADGEKLVTIVEFASWGHSGQEAIDKLRSVKREITSAISRAHRVRVADVVLVATGSIPVTTSGKVRRSSCAERYRNDGFTRLDRSA
What is the function of this protein?
Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the multifunctional polyketide synthase PpsA for further chain extension.  Involved in the biosynthesis of phenolphthiocerol, which is an important intermediate in the biosynthesis of phenolic glycolipid (PGL), also called mycosid B.
What are the official names of this protein?
4-hydroxyphenylalkanoate adenylyltransferase, Acyl-AMP synthase, Long-chain-fatty-acid--AMP ligase FadD29, FAAL.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PNP_FUSNN
Sequence: MKELMFDEKIMELELAGRTLKVSTGKISRQSSGAIVIQYGDTVLLSTANRSKEARKGADFFPLTVDYIEKFYSSGKFPGGFNKREGRPSTNATLVARLIDRPIRPMFPDGFNYDVHIVNTVLSYDEINIPDYLGVIGSSLALMISDIPFLGPVASVIVGYKNGEFILNPSPKELEESELDLIVAGTKEAVNMVEAGAKELDEETMLKAIMFAHENIKKICEFQEEFSKLYGKENIEFEKPEVLTLVKDFIDTNGYERLQQAVLTTGKKNREDAVDSLEEELMEKFIQENYPDVPEEELPEDIILEFKTYYHDLMKKLVREAILYHKHRVDGRTTTEIRPLDAQINVLPIPHGSALFTRGETQSLAITTLGTKEDEQLIDDLEKEYYKKFYLHYNFPPYSVGEVGRMGSPGRRELGHGSLAERALSYVIPTEEEFPYTIRVVSEITESNGSSSQASICGGSLSLMSAGVPIKEHVAGIAMGLIKEGEEFTVLTDIMGLEDHLGDMDFKVAGTKSGITALQMDIKITGITEEIMRIALNQAHQARIQILELMNNTISKPAELKSNVPRIQQITIPKDKIAALIGPGGKNIKGIIEQTGATVDITDDGLVSVFAKDADTLEKTLKLVDSFVREVEYNEVYEGRVVSIMKFGAFMEILPGKEGLLHISEISPERVEKVEDVLSVGDVFKVRVISMEGGKISLSKKKV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VT4_RFVKA
Sequence: MESVVLLLAFISLVCGYVIDPCTPQERSTWHVSIKLCIRVQEYKISSRGCRLTQGPGGLIATGNGFKIFAYDECGHDEHSFLLTNIRESVYASGHGMYAEISNNVTYLDLVSPCARNITIIVSCDDITINAYGKNIDELHPDVTITTLIDTSCVRGHSFAYSINTLCTERLSGESCEQLACQAIKGSQHENYLKACELNAPEQYMFKEYKPHQRPHVAKVLRDEL
What are the official names of this protein?
T4 protein.
What is the protein family that this protein belongs to?
Belongs to the poxviruses B9 family.
Protein: ARC_CATAD
Sequence: MPAHDDDIREGAGRSARGSDDLAAQVTYLEQEIAVLRRRLRDAADAPRGGRAVEERINELQATVAGLTSQNERLVATLREARDQIVALKEEIDRLAQPPSGFGVFLEDVGEGNADIFTGGRKMRVSVSPSIEGGTLRPGQEVMLNEALNVVAAFGFESVGEIVSLKEILEDGSRALVTGRTDEEHVVRLAEPLLESGVKLRPGDALLMEPRSGYVYEVIPKSEVEDLVLEEVPDISYLEIGGLDGQIELIRDAVELPYLHPDLFKEHKLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKVAEVTGSDNVKSYFLNIKGPELLNKYVGETERHIRLVFQRAREKASEGAPVIVFFDEMDSLFRTRGSGISSDVENTIVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAKDIFGKYVTTELPLHADDLAEHSGDRQETVTAMIQATVERMYSEIDENRFLEVTYANGDKEVMYFRDFNSGAMIQNIVDRAKKSAIKDFLDHKQKGLRVSHLLGACVDEFKENEDLPNTTNPDDWARISGKKGERIVFIRTLVTGKRGGDTGRSIDTIASTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: DNAA_HAHCH
Sequence: MTSELWHQCLGYLEDELPAQQFNTWLRPLQAKGSEEELLLFAPNRFVLDWVNEKYIGRINEILSELTSQKAPRISLKIGSITGNSKGQQASKDSAVGATRTTAPSRPVIADVAPSGERNVTVEGAIKHESYLNPTFTFETFVEGKSNQLARAAAMQVADNPGSAYNPLFLYGGVGLGKTHLMQAVGNAIFKKNPNAKILYLHSERFVADMVKALQLNAFNEFKRLYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQMILTCDRYPKEIDHMEERLKSRFGWGLTVMVEPPELETRVAILMKKAEQANVHLSSESAFFIAQKIRSNVRELEGALKLVIANAHFTGQEITPAFIRECLKDLLALHEKQVSIDNIQRTVAEYYKIRIADILSKRRTRSITRPRQMAMALAKELTNHSLPEIGEAFGGRDHTTVLHACKVMIELQQSDPTLRDDYQNFMRMLTS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG057_VACCI
Sequence: MWPFAPVPAGAKCRLVETLPENMDFRSDHLTTFECFNEIITLAKKYIYIASFCCNPLSTTRGALIFDKLKEASEKGIKIIVLLDERGKRNLGELQSHCPDINFITVNIDKKNNVGLLLGCFWVSDDERCYVGNASFTGGSIHTIKTLGVYSDYPPLATDLRRRFDTFKAFNSAKNSWLNLCSAACCLPVSTAYHIKNPIGGVFFTDSPEHLLGYSRDLDTDVVIDKLKSAKTSIDIEHLAIVPTTRVDGNSYYWPDIYNSIIEAAINRGVKIRLLVGNWDKNDVYSMATARSLDALCVQNDLSVKVFTIQNNTKLLIVDDEYVHITSANFDGTHYQNHGFVSFNSIDKQLVSEAKKIFERDWVSSHSKSLKI
What is the function of this protein?
Major envelope protein that plays a role in the biogenesis of the viral double membrane and in egress of virus from the host cell.  Produces the wrapped form of virus that is required for cell-to-cell spread.  Acts as a lipase with broad specificity including phospholipase C, phospholipase A, and triacylglycerol lipase activities.
What are the official names of this protein?
Envelope phospholipase OPG057, 37 kDa protein, Envelope phospholipase F13, Envelope protein F13, Palmitoylated EV membrane protein, p37K.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG057 family.
Protein: SWT15_ORYSI
Sequence: MAFMSMERSTWAFTFGILGNLISLMVFLSPLPTFYRVYRKKSTEGFQSTPYVVTLFSCMLWMYYAFVKSGAELLVTINGVGCVIETVYLAMYLAYAPKSARMLTAKMLLGLNIGLFGVIALVTLLLSRGELRVHVLGWICVAVSLSVFAAPLSIIRLVIRTKSVEFMPFSLSFFLVLSAVIWFLYGLLKKDVFVALPNVLGFVFGVAQMALYMAYRSKKPLVASSSSAAVAAGLETKLPEHVKEVQAVAKGAVAAAPEGRISCGAEVHPIDDVMPSEVVEVKVDDEETNRTDEMAGDGDHAMVRTEQIIKPDMAIVVEV
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET15, OsSWEET15.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ODO1_BACCN
Sequence: MTRKNTATNPWAKFHGPNLGYVIEQYDRYMTNEGSVDPELQELFETFGAPTFQVDVVTGDNKETNFSPQSTGNIETILKAVQVVENIRSFGHLSAHINPMEEPHDGQSLIETMMRELNDVDLKAIPAKTVWPDAPNDVHTALDAIHRLKDVYTKSLAYEFSHIQDSEERTWLHQMVESNSLRQPLSNQKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGVDMLVPVLDEMIAEGAKAGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHATIQSDDKTNHNAGWTGDVKYHLGREQVVGNETVRTRVTLANNPSHLEFVNPVVEGYARAAQENRKKAGYPEQDSSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHIIANNTIGFTTDSYDSRSTRYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRLRFKKDILIDLIGYRRYGHNEMDDPAVTQPQVYKKIKNHPTVRAIYAEQLKAEGVLSSDEVETITQFTQEQLKAEYAQVPPADTSEAAIHVKVPDVVARGIQPIDTGLPLETLRAINEGLLSWPEGFNVYPKVKKILERRRTALDADGKVEWALAESLAFASILQEGTPIRLTGQDSQRGTFAQRHIVLHDTETNETYSPLHRLPNINASFSVHNSPLSEAAVVGFEYGYNVFAPETLVMWEAQYGDFANTAQALFDQYVSSGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSAAQYFHILRRQASILGTEAVRPLVIMTPKSLLRHPLTASTGSELSEGCFQPALEQEKLGTKPTKVKRLIFTTGKMAIDLAAEIESGKHEYNLDELHIVRIEQLYPFPAEKVQSIIKRFKNLEEIIWVQEEPRNMGAWHYMAPILFELAGDKLKTGYIGRPDRSSPSGGDPHAHKAEQELIIAHALDTNYNFRQDKQEIEVYSN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: XPT_LACH4
Sequence: MKLLEDRIKKDGEVLDGDVLKINSFLNHQVDPQLMMQCGEEFKRLFADQKIDKVLTCEASGIAPGVMTAYVLDVPMVFARKKKPSTLNDAVYWADVFSYTKKVNNKICVEEKLLHKGENLLIIDDFVAQGEAVKGMVNIAKQAECNIVGVGAVVAKTFQGGSDWVKQHGLHFEALASIDSFKDGQVHFGKEN
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.