PharMolix/UniProtQA huggingface dataset:
Protein: CLCA_HUMAN
Sequence: MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.  Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed:15858577, PubMed:21297582).
What are the official names of this protein?
Clathrin light chain A, Lca.
What is the protein family that this protein belongs to?
Belongs to the clathrin light chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic face of coated pits and vesicles. In complex with TACC3 and CKAP5 (forming the TACC3/ch-TOG/clathrin complex) localized to inter-microtubule bridges in mitotic spindles.
Protein: SEPF_PROM5
Sequence: MSLISRLKAVVAGDDYLDDDFDELDYASEDELNGVNDYKENRKNSNALSNSNPFDFMNNNRSSNVVGMPGISNSSSEVSLMEPRSFDEMPQAIQALRERKTVILNLTMMDPDQAQRAVDFVAGGTYAIDGHQERVGESIFLFAPSCVNVTSSFPEEVSPSNISSKKTSPYSLETNTTPEPAWGESKLSAFS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: SYG_BORBU
Sequence: MVRMEDIISLAKRKGFVFQSSEVYGGLSGAWDYGPLGVELKKNIKKEWWKSMVYLHENIVGLDSAIFMRPEIWRASGHVDGFSDSMVDCKDCKSRFRADFIDLSKNCPNCKVGNNFTSPRSFNLMFKTHIGVVEDSSSEVYLRPETAQGIFVNFRNVLDSSRLKIPFGIAQVGKAFRNEIVTKNFIFRTCEFEQMEMQFFVHPKQIDEWFCYWQQNRMNFFIETLKISPDRLRFKAHDSTQLAHYAKAAFDIEYEFPFGFQEVEGIHNRGNYDLTQHAKFSNKPKVFEYHDLLTKEKYVPYVIETSAGLTRSVLMTLCDAYSEEELSDGDKRIVLRLHPKLAPYKIAIFPLVKKVELTEIARRIYMELCDDFHIFYDDSGTIGKRYRRQDEIGTPYCVTIDYNTIEDETVTVRERNSMTQKRIFINDLYSYIKTEILNYKEDFNK
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPE36_UPEMJ
Sequence: GVIDAAKKVVNVLKNLF
What is the function of this protein?
Shows antibacterial activity against B. cereus, L. lactis, L. innocua, M. luteus, S. aureus, S. epidermidis and S. uberis.
What are the official names of this protein?
Uperin-3.6.
What are the subcellular locations of this protein?
Secreted.
Protein: INSB_SHIFL
Sequence: MIVCAEMDEHWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLLSAFEVVVWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element IS1 protein InsB.
What is the protein family that this protein belongs to?
Belongs to the transposase 27 family.
Protein: PIMT_DESVV
Sequence: MRRNRERMVRQQLMPRGISDEAVLAAMGCVPRHLFVQEALRAQAYEDHPLPIGNGQTISQPFIVAFMSQLLEAKPGMRVLEIGTGSGYQAAVLAEMGLDVYTVERIREIYQTTRDLLRALRYTRIRCRLDDGTLGWPESAPFDRIIVTAGGPEIPVPLVEQLADPGVMVLPVGVSRRSQELVVVRKRDGKLFRSNRGGVSFVDLVGCHGW
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHCR7_MOUSE
Sequence: MASKSQHNAPKVKSPNGKAGSQGQWGRAWEVDWFSLASIIFLLLFAPFIVYYFIMACDQYSCSLTAPALDIATGHASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAGVVNKYEVNGLQAWLITHILWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGILLLGLVGYYIFRMTNHQKDLFRRTDGRCLIWGKKPKAIECSYTSADGLKHHSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYTAAVPYRLLPGIF
What is the function of this protein?
7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway.
What are the official names of this protein?
7-dehydrocholesterol reductase, 7-DHC reductase, Sterol Delta(7)-reductase.
What is the protein family that this protein belongs to?
Belongs to the ERG4/ERG24 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YCF48_SYNSC
Sequence: MKRLLNSATQLLLVLVLGISLSGCVTTHVPTATTSPWQAMDLDTQANPLDVAFTDSSHGYLVGSNRMIRETNDGGAHWNERSLDLPDEENFRLISIDFSGDEGWIAGQPGLLMHSDDGGQNWTRLFLDTKLPGEPYLITALGSHSAELATNVGAVYETHNDGSSWEAKVTDAAGAVRDLRRSKDGSYVSVSGLGNFYATWEPGDSVWQVHQRVSSQRLQSIGFQPDGNLWMVARGAQIRLNDEPGDFDSWSKAIIPITNGYGYMDLAWDDDGAIWAGGGNGTLLVSRDGGDSWENDPVGDRQPSNFTRMVFDGEHAFVLGERGNLLRWVDNAV
What is the function of this protein?
A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly.  Also plays a role in replacement of photodamaged D1 (psbA).  Assists YidC in synthesis of chlorophyll-binding proteins.
What are the official names of this protein?
Photosystem II assembly lipoprotein Ycf48.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Lipid-anchor; Lumenal side. Note=Associated with a PSII precusor complex on the lumenal side of the thylakoid membrane.
Protein: NADK_NEIMB
Sequence: MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVGCHIVNKTELGQYCDLVAVLGGDGTFLSVAREIALRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERAIALNDAVLSRGGAGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVTQGGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQLV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMB_NEIMA
Sequence: MANQRPIYGFHAVNARLWQNPKSIVELYIQEGKSDARTREVLEKAANENIRVYFADADRLNAISKGARHQGVVGFIDASKNHVHLEDVLENLSEPPLLLILDGITDPHNLGACLRTADAMGVHAVIAPKDKSAGLNATVSKVASGAAETVPYITVTNLARTLRELKEYGIWIIGTDMGGNADLYHCDLPDSAAWVMGNEGDGMRRLTREHCDMLVSIPMFGTVESMNVSVSAGMVLSETRRQRVLKNEKA
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BURCM
Sequence: MGQKIHPTGFRLAVSRNWASRWYANNNNFAAMLQEDIGVREYLKKKLKNASVGRVVIERPAKNARITIYSSRPGVVIGKKGEDIEQLKTELQRRMGVPVHVNIEEIRKPETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRLGAQGIKIMSAGRLNGIEIARTEWYREGRVPLHTLRADIDYATSEAKTTYGIIGVKVWVYKGDTLGRNDAPVVEEVAEDKRPRRNARPGDRRPRRDGEGGAPGARRGAPRRGAGKPEDGKTGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ADD_CLOK1
Sequence: MNLNKILKLIPKTDLHCHLDGSLRPETILDIAYKENIPLPNKELANFQEEIKVIGKCTSLKEYLNKFNLPIQIMQKEEHIYRVTLELLEDALKQNIKYIEIRFAPFNHLKDGLTLDQVINTVLTAMNYGRTHLNIMSNLILCILRQEPVEKGIELVNTAKKYVGKGVVAVDLAGNESDFPPEIHEEAFTLARKYGLHRTVHAGETGLPENIIKSINILGAERIGHGTYAYKDKEIITCLKENRIPLEVCITSNVNTSAVTSYQEHPIKKYLDEDLIITVNTDNTTVSNTNLIEEFNYLIKYQSFRFDDIKKVIKNGIESSFASKEDINKLYEEYLSAINVIELTNPIL
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: RSMG_STRPZ
Sequence: MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAITEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDSLNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELTIPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKKKETPYKYPRKAGLPNKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMPS3_MYCTO
Sequence: MSGPNPPGREPDEPESEPVSDTGDERASGNHLPPVAGGGDKLPSDQTGETDAYSRAYSAPESEHVTGGPYVPADLRLYDYDDYEESSDLDDELAAPRWPWVVGVAAIIAAVALVVSVSLLVTRPHTSKLATGDTTSSAPPVQDEITTTKPAPPPPPPAPPPTTEIPTATETQTVTVTPPPPPPPATTTAPPPATTTTAAAPPPTTTTPTGPRQVTYSVTGTKAPGDIISVTYVDAAGRRRTQHNVYIPWSMTVTPISQSDVGSVEASSLFRVSKLNCSITTSDGTVLSSNSNDGPQTSC
What are the official names of this protein?
Probable transport accessory protein MmpS3.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RIMM_CHLPD
Sequence: MDLFLTGTILKPKGLKGEVKVLPVTDFPELFLSRKSYLAGKSDASVMPLNVLKASLSKGFAWLFFEGVDTLEKAEKLSGMHLFVEEKELARQPTGRAYLHELIGMKVLDGNRYEAGVISDILKMPAHEVYEVQANGRKILIPAVEEFVEEIDMAGRYMVVPRFDEFL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B1M_HUMAN
Sequence: MPEPVKSAPVPKKGSKKAINKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 1-M, Histone H2B.e, H2B/e.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MIAA_GRABC
Sequence: MKEKRALFVAGPTCSGKSALALAVAERLGGTVINADSMQIYRELRILTARPDQEEEARVPHRLYGVLPASQPGSAAWWRDQAITAMEESWQQGRLPILCGGTGLYFHALMHGFADIPDPGEEARQEARSLLAELGPESLHARLAEADPATAARLKPQDSQRIARAWEVWRGTESGLSAWQNQPPRPLPGWDFAAIRIDPPREELRQAITARLHGMLDNGALAEVEALRVQALDPSLPAMRAHGVPEFLAFLRGDISLPEAMQRAAQATIRYTKRQATWFRNRPFVKPPFLYTIDARIASFQQLSERSMADMLNFIRAFH
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ATG5_KLULA
Sequence: MEELRERVWHGSLNVEIMLSDSIVVPNTPLSEKCYHIVVLRESFLALYLPAIVRKLGNNVIVTYENPYKQWWFEYDGVPVPWEYPCGVLFDFLCNSSTTSTGKEDDQRLQMWKLKLCHGNKYPPGILPLVDGLRQVKDHWKHQWKQACFILNGSAKRIMSLSIPDFEAFWQSLISRHQPDYIKVREKLLTPNKTKHIPIRVWTADASFLQPSIPANSDTMTLFDVMTSMDIKLQENNRAIIQGIVICSDEDIINLYDLFASIDGFLYVVIK
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RL27_AGRRK
Sequence: MAHKKAGGSSRNGRDSQSKRLGVKKFGGEAVIAGNIIVRQRGTEWHPGTNVGLGKDHTIFALTAGNVNYRTKANGRVYVSVMPKAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: NRAM_I63A1
Sequence: MNPNQKIITIGSVSLGLVVLNILLHIVSITITVLVLPGNGNNGSCNETVIREYNETVRIEKIIQWHNTNVIEYIERPESDHFMNNTEPLCDAKGFAPFSKDNGIRIGSRGHVFVIREPFVSCSPTECRTFFLTQGSLLNDKHSNGTVKDRSPYRTLMSVEIGQSPNVYQARFEAVAWSATACHDGKKWMTIGVTGPDAKAVAVVHYGGIPTDVINSWAGDILRTQESSCTCIQGECYWVMTDGPANRQAQYRAFKAKQGKIIGQTEISFNGGHIEECSCYPNEGKVECVCRDNWTGTNRPVLVISSDLSYRVGYLCAGLPSDTPRGEDSQFTGSCTSPMGNQGYGVKGFGFRQGNDVWMGRTISRTSRSGFEILKVRNGWIQNSKEQIKRQVVVDNLNWSGYSGSFTLPVELTRRNCLVPCFWVEMIRGKPEEKTIWTSSSSIVMCGVDHEIADWSWHDGAILPFDIDKM
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: ERPA_PSEU2
Sequence: MSVESFTPTALEFTPNAAHKVKTLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVADDDTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNASTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: INVA_VIGRR
Sequence: MEHHKPLLPTSSHAAPTSSTRKDLLFVLCGLLFLSSLVAYGGYRASGVPHAHLSSPTSNHQQDHQSPTSLPSSKWYPVSRGVSSGVSEKSSNLLFAGEGGASEAFPWDNSMLSWQRTSFHFQPEKNWMNDPNGPMYYKGWYHFFYQYNPNGAVWGDIVWGHAVSRDMIHWLHLPLAMVADQWYDKQGVWTGSATILPNGEIIMLYTGSTNESVQVQNLAYPADPSDPLLLDWIKHTGNPVLVPPPGIGAKDFRDPTTAWLTSEGKWRITIGSKLNKTGIALVYDTEDFKTYELKEGLLRAVPGTGMWECVDFFPVSKKNGNGLDTSVNGAEVKHVMKVSLDDDRHDYYAIGTYDDNKVLFTPDDVKNDVGVGLRYDYGIFYASKTFYDQNKDRRILWGWIGESDSEYADVTKGWASVQSIPRTVRLDTKTGSNLLQWPVDEVESLRLRSDEFKSLKAKPGSVVSLDIETATQLDVVAEFEIDTESLEKTAESNEEFTCSSSGGAAQRGALGPFGLLVLADEGLSEYTPVYFYVIKGRNGNLRTSFCSDQSRSSQANDVRKQIFGSVVPVLKGEKFSLRMLVDHSIVESFAQGGRTCVTSRVYPTKAIYGAARLFLFNNATEATVTASLKVWQMNSAFIRPFPFNPDQKS
What is the function of this protein?
Possible role in the continued mobilization of sucrose to sink organs.
What are the official names of this protein?
Acid beta-fructofuranosidase, Acid invertase, AI, Acid sucrose hydrolase, Vacuolar invertase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Vacuole lumen. Note=May be released into the lumen of the vacuole from the tonoplast through a proteolytic processing.
Protein: APT1_YEAST
Sequence: MSIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLNAQKEALKK
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase 1, APRT 1.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CU18B_LOCMI
Sequence: GYLGAPAVVAPGAPLAARGYAAPAYAAPLARYAAPVARAYAAPVARAYAPAVAATPAAVEYDPHPQYSFAYNVQDAHTGDSKTQHESRDGDVVQGSYSLAEPDGSIRTVDYTADPVNGFNAVVHKEAGAHPAAAPVAVAAPVAHAPVAVAAPVRAYAAPLARAAYAAPIARAAYGPALAYGGAYH
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 18.6, isoform B, LM-ACP 18.6B, LM-18.6B.
Protein: IHFA_XANOM
Sequence: MALTKAEMAERLFDEVGLNKREAKEFVDAFFDVLRDALEQGRQVKLSGFGNFDLRRKNQRPGRNPKTGEEIPISARTVVTFRPGQKLKERVEAYAGSGQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CU317_LATCU
Sequence: IPYGGNGVHHGKAGDSXTVDTAIGNIGNNAASIIGGMISGWASGLAG
What is the function of this protein?
Has bactericidal activity against various Gram-negative Campylobacter, and the Gram-positive L. monocytogenes and B. subtilis.  In vitro, inhibits C. jejuni strain ATCC 33560 (MIC=27. 3 ug/ml).
What are the official names of this protein?
Bacteriocin curvaticin DN317.
What is the protein family that this protein belongs to?
Belongs to the bacteriocin class IIA/YGNGV family.
What are the subcellular locations of this protein?
Secreted.
Protein: H4_SOLCH
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDSVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ISPE_BACC7
Sequence: MKLLVKAPAKINLSLDVLGKRQDGYHEVKMIMTTIDLADRLELMELAEDRIEILSHNRYVPDDQRNLAYQAAKLLKEKFNVKKGVSITIEKTIPVAAGLAGGSSDAAATLRGLNKLWNLGLTIDQLAELGAEIGSDVSFCVYGGTAIATGRGEQIEHIKTPPSCWVILAKPHIGVSTADVYGNLKLNRVTHPNVDKMVDVINAGDYKGICDTVGNVLEDVTFAMHPEVARIKAQMKRFGADAVLMSGSGPTVFGLVHHDSRMHRIYNGLKGFCEQVYAVRLLGERETLE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MRAZ_HALH5
Sequence: MFMGEYRHNVDEKGRMIIPAKFREELGETFVVTRGLDRCLFVYPQVEWKKLEESLKNLPFTKKDARAFTRFFFSGATECELDKQGRVNIASPLREFAQLKKECVVIGVSNRVEIWSKELWEEYFAESEESFSEIAENIVDFDL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
Protein: FMT_STRR6
Sequence: MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKSEEEKLNWNKTNRQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.