PharMolix/UniProtQA huggingface dataset:
Protein: RS6_RHOP5
Sequence: MPLYEHVFLARQDASTQQVEELTTQITGVIEGLGGKVVKMEAWGVRSLTYRMNKNRKAHFVLLNIDGPSAVVAEVERQERINEDVIRYLTVRVDEHEEGPSAMMRKADRDRDRDERGGGGFRGDREGGFRGDREGGGFRGDRGPRRPRDDAPAATEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PSA6_RAT
Sequence: MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-6, Macropain iota chain, Multicatalytic endopeptidase complex iota chain, Proteasome iota chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
Protein: Y1076_PASMU
Sequence: MLFSKSKRGYLFMIKSEKRCFQLIKHSVYKILHAVFYHMVLFISLRLGKCQSQYALLCKQDDKQRFLRRARWVEFAIVALT
What are the official names of this protein?
Uncharacterized protein PM1076.
Protein: PIPNA_MOUSE
Sequence: MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAIYIDIADRSQVLSKDYKAEEDPAKFKSVKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQEKRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:8049244).  Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (By similarity).  Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol transfer protein alpha isoform, PI-TP-alpha, PtdIns transfer protein alpha, PtdInsTP alpha.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COX2_LEMBA
Sequence: MAYPFQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAAILILIALPSLRILYMMDEINNPALTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVSSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COAD_SYNR3
Sequence: MRALYPGSFDPVTFGHLDLIQRASQLFDEVIVAVLRNPNKQPSFSLEERLEQLSSVTSHLPQVRVTSFEGLTVHFALEQDARVILRGLRALSDFEFELQLAHTNASLSGQVDTLFMATAVPHSFLSSSVVKEVARFGGDVQHLVPETVAIDLRRLFNQRVDVGGDR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_SALPK
Sequence: MSEQNAQGADEVVDLNNEMKARREKLAALREQGIPFPNDFRRDRTSDQLHAEFDAKEAEELEALNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTFKTRSKILAGIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDVLGTTQVPYGDEVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVNAKAAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIJ_BUCAP
Sequence: MKYKKKIFSILENLEKKNIEKDIINIKNLYLQKEKYVTQLSLLKDYQNEYLIKLKSKIELGICLYQWRNYNNFIFILYFLIKDNEQKIKKNQKILEKSLKQYSKNQIKLKTWNYLYKKYKKKEIKKILLVEEMISDEFSQLKNLAEGSCYNV
What is the function of this protein?
Flagellar protein that affects chemotactic events.
What are the official names of this protein?
Flagellar FliJ protein.
What is the protein family that this protein belongs to?
Belongs to the FliJ family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PHYDA_ECO81
Sequence: MRVLIKNGIVVNADGQAKQDLLIESGIVRQLGTDISPQLPCEEIDASGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRQQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRISPERFVELTSAMPARLFGLWPQKGILAPGSDGDVVIIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL
What is the function of this protein?
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'-position.  Has no activity on dihydropyrimidines.  The physiological function is unknown.
What are the official names of this protein?
D-phenylhydantoinase, Hydantoin-utilizing enzyme HyuA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: PUR5_THEAC
Sequence: MSEVEGGIINRKLQGEFVNTFIRQLKFHREDFKNIGYIGGFTSIIDMGNFGITFNNDGVGTKAMIAEAVNKYDTLGIDCVAMNVNDAITVGSEPIAMVDYLAVNKMDEEMAKQLGTGFNVGAQMANISIVGGETAVLPDVVKHIDISGAVIGIVQKNQIITGSNIKEGDVIIGLGSSGLHSNGFTTVRKIIADNNLDLQDTFPGDSKKTYEVLLEPTRIYVREILDIMGIITIKGMANITGGGFKNITRMKDMKYVIDDPFEPQNVFIRLMEMGNLNYAQMFEIFNMGTGFVLVIDEDEKVDIMNALKGKVPVKVMGHVENGSGVEIPKYEVSLKGYY
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXA_STAAN
Sequence: MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTADAVQEQDQQLSNNFGLQ
What is the function of this protein?
Virulence factor that is important for the establishment of infection in the host.  EsxA is required for EsxB synthesis as well as secretion (By similarity).  Modulates host cell apoptotic pathways and mediates together with EsxB the release of S. aureus from the host cell.  By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity (By similarity).
What are the official names of this protein?
Type VII secretion system extracellular protein A, Ess extracellular protein A.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. sagEsxA-like subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: Y1396_HAEIN
Sequence: MTEREKIIQQQKQLKALFSVWMKEKMNHEVVIFQKTDGKIVEHYPDGSEKIVGYAK
What are the official names of this protein?
Uncharacterized protein HI_1396.
Protein: SYC_PSEF5
Sequence: MLTIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLITRWLRFSGYDLTYVRNITDIDDKIINRANENGEAFEALTERMIAAMHEDEARLNIKKPDMEPRATDHIPGMHTMIQTLIDKGYAYAPGNGDVYYRVGKFMGYGKLSRKKIEDLRIGARIEVDESKQDPLDFVLWKAAKPGEPSWPSPWGDGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIAQSEAATGKTYANAWMHCGMIRINGEKMSKSLNNFFTIRDVLDKYHPEVVRYLLVASHYRSAINYSEDNLKDAKGALERFYHALKGLPKVAPAGGEAFVERFTQVMNDDFGTPEACAVLFEMVREINRLRESDIDAAAGLAARLKELASVLGVLQLEADDFLQAGAEGRVDGAQVEALIQARLAARANKDWAESDRIRDQITAMGVILEDGKGGTTWRLAD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_ECO27
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RETR1_HUMAN
Sequence: MASPAPPEHAEEGCPAPAAEEQAPPSPPPPQASPAERQQQEEEAQEAGAAEGAGLQVEEAAGRAAAAVTWLLGEPVLWLGCRADELLSWKRPLRSLLGFVAANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRTRGAQLWRSLSESWEVINSKPDERPRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLCAFLCPLFKCNDIGQKIYSKIKSVLLKLDFGIGEYINQKKRERSEADKEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPSEEVFSRDLSDFPSLENGMGTNDEDELSLGLPTELKRKKEQLDSGHRPSKETQSAAGLTLPLNSDQTFHLMSNLAGDVITAAVTAAIKDQLEGVQQALSQAAPIPEEDTDTEEGDDFELLDQSELDQIESELGLTQDQEAEAQQNKKSSGFLSNLLGGH
What is the function of this protein?
(Microbial infection) During SARS-CoV-2 infection, RETREG1-mediated reticulophagy is promoted by SARS-CoV-2 ORF3A protein (PubMed:35239449).  This induces endoplasmic reticulum stress and inflammatory responses and facilitates viral infection (PubMed:35239449).
What are the official names of this protein?
Reticulophagy regulator 1, Reticulophagy receptor 1.
What is the protein family that this protein belongs to?
Belongs to the RETREG family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ZIPA_VIBVY
Sequence: MQELRFVLIVVGALAIMALLFHGLWTSKKEGKAKFGDKPLSKLDLGESEPKESEMYVAPEDDYEIIRKERKEPAFEDEKPFSTSGVIGDPLIDDLHSGQDKENKFSQPKFDDDITVAEAEAAASIEQDAPAWVEQPQEIDEPLTHHPDEIDAFSGEETIVELDEPISKTVEPELQVIVLNVHCAGDSPFVGTKLFDSMQQNGLVYGEMDIFHRHLDMSGTGKVLFSVANMMHPGTLKHDDPAEFSTKGISFFMTLPCYGEADQNFNLMLKTAQKIADDLGGNVLDDKRNLMTPDRLAGYRRQIVEFKAANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: HSP72_SOLLC
Sequence: MAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVGFTDSERLIGDAAKNQVAMNPINTVFDAKRLIGRRFSDASVQSDMKLWPFKVIPGPGDKPMIVVNYKGEEKQFSAEEISSMVLIKMKEIAEAFLGTTVKNAVVTVPAYSNDSQRQATKDAGVISGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDITGNPRALRRLRTACERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKSTVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERTRTRDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGTLNVSAEDKTTGQKNKITITNDKGRLSKEEIEKMVQEAEKYKSEDEEHKKKVEAKNALENYAYNMRNTIKDEKIASKLSADDRTKIEDAIEQAIQWLDGNQLAEAEEFEDKMKELESLCNPIIAKMYQGAGGDMDDEGPAPSGGGAGPKIEEVD
What are the official names of this protein?
Heat shock cognate 70 kDa protein 2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HSP7B_ENCCU
Sequence: MSEEKAKSNTSRAIGIDLGTTFSCVAGYISGKVEVITNQDGERTTPSVVSFDENNCTVVGTAARNMVGSDPMSVIFDAKRMIGREFDDPKIQNAIKGWPFKVVRYNHREKREEPNKVSEGSNSYDNIAIKITRNGKTNYYAPVEISGKVLLYLKNAAEARLGGTVDSAVVTVPAYFEEPQKDVTKAAATIAGFDPNKVRLLAEPTAAAMAYGHIQTQKNANFSAKEDVLVFDLGGGTFDVSLLDFEFNGAAGSLGIVKAIDGDTFLGGQDFDNLLINYCISEFLKKNSSIKQSDLKESALLRLRAECTRVKAVLSSATSSAIYVPCFHMTDDLNVQITRARFELLCDHLFRRCMERTKGCLLRSAGVPEVEYSADGSKLLLNPSLEKTLNEVKNNISKVLLVGGSSRIPKIKALLAEYFGAHKVIEPVNADEAVAYGAAYQAASIYSDAVDAGSSLLLIDCVPLNLSIETAGGVATALIHCGDNIPIKKTETFTTYEDNQTAVTINVYEGNRAMCKDNKKIGSFNLDGIIAAPRGVPKIEVTFDVDHNGILIVTAQDKQTGKENQIKVTNSQNRLSQEEIERMTKEARDNEQRDNETKEKMGKRMAFDQAISSFKAFVEKANNISEEKKSESLRVIKENEEWLSNAQRPEDFEVEELERRSNDFQSFTSDIMKDVGMGGAPAA
What are the official names of this protein?
Heat shock protein homolog ECU03_0520.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_STRS2
Sequence: MINAQEISALLKQQIEGFQPDFDYTETGVVTYIGDGIARAQGLDNAMSGELLVFENGTIGMAQNLETNDVGIIILGQFTDIREGSVVRRTGKIMEVPVGSALIGRVINPLGQPVDGLGEIRTSKTRPIEYPAPGVMQRKSVNEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYEGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLKDDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEVLKQPLHKPLPVEKQVLILYALTNGFLDSVPIDDILAFEEELYAYFDLHYDGLLDVIRTTKDLPDTDELNAAIQAFKDQSVFK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CAR17_HUMAN
Sequence: MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDSVIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS
What is the function of this protein?
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation.  Inhibits the release of IL1B in response to LPS in monocytes.  However, unlike CASP1, do not induce NF-kappa-B activation.
What are the official names of this protein?
Putative caspase recruitment domain-containing protein 17P, Caspase-1 inhibitor INCA, Inhibitory caspase recruitment domain protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_LEGPH
Sequence: MATPLKLYRNIGIAAHVDAGKTTTTERVLYYTGMSHKIGEVHDGAATMDWMVQEQERGITITSAATTCYWSGMDKQFESHRINIIDTPGHVDFMIEVERSLRVLDGAVVVFDSVAGVEPQSETVWRQANKYGVPRIVFVNKMDRMGANFLRVVSQIKQRLGSTPVVLQLPIGAEEEFKGVIDLIKMKAIHWDEENKGMTFKYVDIPADLKSTCEEYRAHIIEAAAEYSEELMEKYLEGEEFTEAEIKKALRHLTITNKVVPVFCGSAFKNKGVQAVLDGVIEYLPSPTDIPDIQGVDEHGDVIHRKTSYDEPFSALAFKIATDPFVGTLTYFRAYSGILKSGDTVYNSVKGKKERIGRLLQMHANSREEIKEVRAGDIAAAVGLKTVTTGDTLCDQDKVVILERMDFPDPVIAVAVEPKTKADQEKMGIALGKLAQEDPSFRVHTDEESGQTIIQGMGELHLEIIVDRMKREFNVEANVGKPQVAYRETLKQAVEQEGKFVRQSGGRGQYGHVWLKIEPQEPGKGYEFINAIVGGVIPKEYIPAVDKGIQEQMQNGVIAGYPVVDVKVTLFDGSFHEVDSSEMAFKIAGSQCFKQGALKAKPVLLEPIMSVEVVTPEDYMGDVMGDLNRRRGLVQGMEDSPAGKIVRAEVPLAEMFGYSTDLRSATQGRATYTMEFCKYAEAPTNIAEAIIKKQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARP3C_HUMAN
Sequence: MFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDVDPQKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDSMESISDVVDEVIQNCPIDVRRPLYKMEQIPLSYPQGHGFHPLSPPFH
What is the function of this protein?
May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells.
What are the official names of this protein?
Actin-related protein 3C, Actin-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the actin family.
Protein: HSLU_SALDC
Sequence: MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQAEQQQEPSAARQTFRKKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGARRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROP_STAAM
Sequence: MDFNKENINMVDAKKAKKTVVATGIGNAMEWFDFGVYAYTTAYIGANFFSPVENADIRQMLTFAALAIAFLLRPIGGVVFGIIGDKYGRKVVLTSTIILMAFSTLTIGLLPSYDQIGLWAPILLLLARVLQGFSTGGEYAGAMTYVAESSPDKRRNSLGSGLEIGTLSGYIAASIMIAVLTFFLTDEQMASFGWRIPFLLGLFLGLFGLYLRRKLEESPVFENDVATQPERDNINFLQIIRFYYKDIFVCFVAVVFFNVTNYMVTAYLPTYLEQVIKLDATTTSVLITCVMAIMIPLALMFGKLADKIGEKKVFLIGTGGLTLFSIIAFMLLHSQSFVVIVIGIFILGFFLSTYEATMPGSLPTMFYSHIRYRTLSVTFNISVSIFGGTTPLVATWLVTKTGDPLAPAYYLTAISVIGFLVITFLHLSTAGKSLKGSYPNVDNEQDRAYYAEHPKEALWWVKERKN
What is the function of this protein?
May be a proton symporter involved in the uptake of osmolytes such as proline and glycine betaine.
What are the official names of this protein?
Putative proline/betaine transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBX1_CAEEL
Sequence: MAQASDSTAMEVEEATNQTVKKRFEVKKWSAVALWAWDIQVDNCAICRNHIMDLCIECQANQAAGLKDECTVAWGNCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
What is the function of this protein?
Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate (By similarity).  Essential for meiosis, mitotic chromosomal condensation and cytokinesis.  Involved in histone H3 phosphorylation.
What are the official names of this protein?
RING-box protein 1, Rbx1, Ce-rbx-1.
What is the protein family that this protein belongs to?
Belongs to the RING-box family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSBP_NARPS
Sequence: MASTACFLHHHAPSPATSNLSRTRSATNRDEQQQEHSARLQSPEADCATENDALLSRRLALTILIGGAALGSRVSAADAAYGESANVFGKPKTNTDFQTVTGDGFKILIPSKWNPSKEVEFPGQVLRYEDNFDTTSNVGVMVNPTDKKSIKDYGSPEQFLSQVDYLLGKQAYFGKTISEGGFEPNAVRTANILETSTPVVGGKDYYSIHVLTRTADGDEGGKHLLITATVSDGKLYICKAQAGDKRWFKGAKKFVESAASSFSAA
What is the function of this protein?
May be involved in the regulation of photosystem II.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, chloroplastic, OEE2, 23 kDa subunit of oxygen evolving system of photosystem II, 23 kDa thylakoid membrane protein, OEC 23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: Y1285_ARATH
Sequence: MSTEDALCFTGEEYARHVREYWRGVAESDGFDSEDIRSPVVLTGLFHYDCQSGRRYPDPLLVKRYALLGLHRFNILQGTSFELDALQKFNKTMNLTSSYYITLLANEPGAIPLQKTFQVRVDERKYDTLDLTVAIARLKKDQNEAAETTKEPFVPHFCCSAVSDGVFQGPLPDWPSDDALRHDRNRFYELEKSEWQATDWISLYLELLILATDRGMFGVAQTGLPQVQILKVVIETEEENEKPLDKRLNARRAHVYITFTGLPKSPRLVEIGEHVERKAIIRRVIDDSGYLTLLGKFWSGKDTEQRSKTRQSEEKVESSQKRSRLC
What are the official names of this protein?
Putative UPF0725 protein At1g28500.
What is the protein family that this protein belongs to?
Belongs to the UPF0725 (EMB2204) family.
Protein: AROQ_PHOLL
Sequence: MAGKFHILLLNGPNLNMLGTREPDIYGSLTLDDIVSKLSEEAHQSGVKFSHLQSNAEFELINRIHSAQGNTDFILINPAAFTHTSVALRDALLTVKIPFIEIHLSNVHAREPFRHHSYLSDLAVGVICGLGVDGYSFALQAAVNRLSKFN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.