PharMolix/UniProtQA huggingface dataset:
Protein: GIMD1_RAT
Sequence: MDANKMIINLAVLGKTQSGKSSAGNVLLGSADFYSRFAPGSVTKDCSLGRSCHIHGFMRRGGHEISLQIQVLDTPGYPHSKLSTRCVKQEVKKALEHHFGQEGLHLALLVHRADMPFFGQEASDSVQLIQELLGDSWKNYTAILFTHAEKIKEAGLSEEEYLCEASDALLTLLNSVQHRHIFLYERGNSWSEQRIKILERIMEFIKENHFQVLSFT
What are the official names of this protein?
GTPase IMAP family member GIMD1, GIMAP family P-loop NTPase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
Protein: DER_SYNP6
Sequence: MPLPIVAILGRPNVGKSTLVNRLAGSREAIVHDEPGVTRDRTYQEAFWCDRDFTVVDTGGLVFDDDTEFLPLIREQAELALAEAALAVLVVDGQAGLTAADNEIADWLRHQNRPIVVAVNKCESPDKGAAQAAEFWSLGFGEPLPISSIHGSGTGELLDRVLELLPPADEAAGDETEIGVAIVGRPNVGKSSLLNSFLGEQRAIVSPIAGTTRDAIDTVIERNDQRYRLVDTAGIRRKRGVDYGPEFFGINRSFKAIRRADVCLLVIDVLDGVTDQDQKLAGRIEEDGRACVIVVNKWDAHEKDSSTIYEVERQLRDRLYFLDWAPMIFVSALTGQRVEKILDQVNTVVEQHRRRVGTSVINEVLGDAIAWRTPPTTRQGRQGRIYYGTQVTTQPPSFTLFVNDPKLFGESYRRYIERQFRESLGFSGTPIRLFWRGKKSRELERGANRATRV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SPG21_DANRE
Sequence: MEEIRVSPDYNWFRSTVPLKRIIVDDDDSKVWSLYDAGPKSIRCPIIFLPPVSGTAEVFFQQVLALSGWGYRVISLQYPVYWDLLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAEVTYKSPRVHSLVLCNSFSDTSIFNQTWTANSFWLMPSFMLKKIVLGNFAKGPVDPKMADAIDFMVDRLESLNQSELASRLTLNCQNSYVEPHKIKDIAVTIMDVFDQSALSQEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNLYIQIHLRQFHGTRYAAISPEMVSAEELEVQRTHLSNNSESEDES
What are the official names of this protein?
Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMYG_YEAST
Sequence: MARQKMFYNKLLGMLSVGFGFAWALENITIYEFDFGKGILDQSYGGVFSNNGPSQVQLRDAVLMNGTVVYDSNGAWDSSALEEWLQGQKKVSIEKIFENIGPSAVYPSISPGVVIASPSQTHPDYFYQWIRDSALTINSIVSHSAGPAIETLLQYLNVSFHLQRSNNTLGAGIGYTNDTVALGDPKWNVDNTAFTEDWGRPQNDGPALRSIAILKIIDYIKQSGTDLGAKYPFQSTADIFDDIVRWDLRFIIDHWNSSGFDLWEEVNGMHFFTLLVQLSAVDKSLSYFNASERSSPFVEELRQTRRDISKFLVDPANGFINGKYNYIVGTPMIADTLRSGLDISTLLAANTVHDAPSASHLPFDINDPAVLNTLHHLMLHMRSIYPINDSSKNATGIALGRYPEDVYDGYGFGEGNPWVLATCTASTTLYQLIYRHISEQHDLVVPMNNDCSNAFWSELVFSNLTTLGNDEGYLILEFNTPAFNQTIQKIFQLADSFLVKLKAHVGTDGELSEQFNKYTGFMQGAQHLTWSYTSFWDAYQIRQEVLQSL
What are the official names of this protein?
Glucoamylase, intracellular sporulation-specific, 1,4-alpha-D-glucan glucohydrolase, Glucan 1,4-alpha-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 15 family.
Protein: FABH_STRZP
Sequence: MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRHISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANKAFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDGAGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVFDFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMMEYGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAU76_ARATH
Sequence: MAKGGNKLMKLKSVLKKLNSFNTKPNQPPAQTNHSRSSAVSAFPSEDLQTVYVGRTRRTYHVSSDVVSHPLFQQLAAVDGGCGSEDGSISVSCEVVLFEHLLWMLENADADESRPESVYELVEFYAC
What is the function of this protein?
May be involved in the regulation of ethylene receptor signaling.  Promotes cell expansion and plant growth (Probable).  Involved in the regulation of cell elongation (PubMed:24312429).
What are the official names of this protein?
Auxin-responsive protein SAUR76, Protein SMALL AUXIN UP RNA 76.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: SFSA_DESHD
Sequence: MKYTNIREGQFLSRPNRFIAKVEIDGKEEICHVKNTGRCRELLIPGVTVFLQEADFEHRKTKYDLIGVRKGNRLINMDSQVPNKVFREWLEKGYFQELQHIKQEQTFRNSRFDFYLEAGQRKIFVEVKGVTLEEEGVALFPDAPTERGVKHLRELSQAVAAGYEAYVVFIIQMKDIHYFTPNIKTHQAFGDSLIQAEKQGVKILALDCEVTEDSIEAGDFVTVKLVEG
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RF1_CERSK
Sequence: MVPMDRLLQIVRRFEFLEARLSAGAAPAEIAALSREYAELKPVVVEISAYRTALEDLAEAEAMLSDPEMRALAEDEIPALRARIPGMEQALRLALLPKDAADARPAILEIRPGTGGEEAALFAGDLLRMYQRYAEGQGWRFELLDLAPSELGGIREATARVEGEGAFARLKYESGVHRVQRVPETEAQGRIHTSAATVAVLPEAEEVDLEIPAADLRIDTMRSSGAGGQHVNTTDSAVRITHLPTGIIVTSSEKSQHRNREIAMQVLRARLYDLERQRLADARSADRKAQVGSGDRSERIRTYNFPQGRMTDHRINLTLYALPQIMAGDLSEVISALTAHDQAARLAEMEA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_DROSI
Sequence: MKYATGTDNAMTSGISGQTNNSNSASNEMQPTTSTPTAVHKEATSTATTTATYANGNPNPSANPSQSQPSNALFCEQVTTVTNLFEKWNDCERTVVMYALLKRLRYPSLKFLQYSIDSNLTQNLGTSQTNLSSVVIDINANNPVYLQNLLNAYKTFQPCDLLDAMSSSSSDKDSMPCYGSDFQITTSAQCDERKLYARKEDILHEVLNMLPLLKPGNEEAKLIYLTLIPVAVKDTMQQIVPTELVQQIFSYLLIHPAITSEDRRSLNIWLRHLEDHIQAAAAGLTNRSYFLQPSPQLVAGGSSTGSGSCSSSATSSSTASCSSVASSSLCPASGSRSSRTNDWQTIAPPSKQLQNKLAGDWRGSGGGSSSGSINPLCDNLNGITLNELASSQNSLGLSLEGSSSLVNGVVAGAGSMLGIGGGDDHDTSFSKNGTEILDFDPVTADMGEACSLASSSLCGRNGGNTVEDRSQPPPNLQQQLLQPPPYASILMGNVGDQFGEINRWSLDSKIAALKTRRSNSLTTQTISSCSSSSNSSVITVNDNCSNSTENLAQFANKPRSFSLSIEHQRGALMNSGSDTRLDEFKPNYIKFHTRNVGMSGIGLWLKSLRLHKYIELFKNMTYEEMLLITEDFLQSVGVTKGASHKLALCIDKLKERANILNRVEQELLTGQMELSTAVEELTNIVLTPMKPLESPGPPEENIGLRFLKVIDIVTNTLQQDPYAVQDDETLGVLMWILDRSIHNEAFMNHASQLKDLKFKLSKMKISMVPKMHHVKPAGVGPNNGNINKPRWNGKTRKCDTKSGSNDRINNRKNSNDMLNFSLNCLPHPLPHHSQQAPPPLPQFDYNGYGGGPSHQPQYKSSSYPSFMGNPQQQPPPPPSSKSHHHPQQMQQMLQQHNHFPALPQQTPPQSHRRSLNNLILVAGGPQQPQQLIFKPGQGVLTNNGSNDNLGLERNQQPQQQQQRKLSGGVSSAEQQPKKTMAAVVMENLAKFDQHFTLF
What is the function of this protein?
Translation regulator that binds to the 3'-UTR of specific mRNAs such as nanos (nos) and prevent their translation.  Prevents translation of unlocalized nos in the bulk cytoplasm via the recruitment of cup (By similarity).
What are the official names of this protein?
Protein Smaug.
What is the protein family that this protein belongs to?
Belongs to the SMAUG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_AKKM8
Sequence: MAAPKRRTSKMKQRTRLAAQAWRAPKLRKCQNCGSSTPGHTACPNCGTYTTRSGKEIVVKAEA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CSH1_YEAST
Sequence: MKKELKILIIANIALLISIIHYTFDLLTLCIDDTSKDALTDEQLNPPNGFNSTFYESPPQLIPKIIHQTYKTNDIPEQWVKGRQKCIDLHPDYTYILWTDEMSDTFIKQEYPWFLDTFRSYEYPIERADAIRYFILSHYGGIYIDLDDGCERRLDPLLKVPAFLRKTSPTGVSNDVMGSVPRHPFFLKVIKSLKHYKKNWYIPYMTIMGSTGPLFISVVWKQYKRWSNTAENGAVRILQPADYKMHNNSFFSISKGSSWHTGDANFMKTLENHILSCVVTGFIFGFFILYGEFTFYTWLCSGPFNNKRYYIQWLSDKFKLHKWKLTSSYKNKEKRRNPTRHEYNSRGKRLRKDSNIPYDSVFLDIEKNHAKFTDLT
What is the function of this protein?
Involved in the synthesis of mannosyl phosphorylinositol ceramide (PubMed:12954640).  Catalyzes the addition of mannosyl to phosphorylinositol ceramide (PubMed:12954640).
What are the official names of this protein?
Mannosyl phosphorylinositol ceramide synthase CSH1, CSG1/SUR1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 32 family.
Protein: KATG_XYLFA
Sequence: MLYIYYLFKSLFFHTLFVFSIYKDCPYMRASSPETTSAVKCPFNKTAVEGTHNKDWWPNQLRVDLLHQHSNKSNPLGETFDYAKEFQKLDYAALKRDLHALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRIGDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKKKYGQQISWADLIVLSGNVALESMGFKTFGFAGGRVDTWEPDQDVYWGRETTWLGGDVRYGAVSEGVHHPDEHRGAKEKAAKNSDSRVLENPLAAVQMGLIYVNPEGPDGRPDPLASARDIRETFARMAMNDEETVALIAGGHTFGKTHGAAPADNVGPEPEAGELEQQGLGWHNRFGSGKAGDTITSGLEVTWTKTPTQWSNDFFEHLFGYEWELTKSPAGAYQWVAKNAAATIPHAHDPSKKLLPMMLTSDLALRFDPIYEKISRHFHAHPDQFADVFARAWFKLMHRDMGPRVRYLGPEVPVEELIWQDPVPKVSHVLVDAQDLLALKQKISASGLGISQLVSTAWASASTFRGSDKRGGANGGRLCLAPQSQWEVNQPQQLSVVLETLRRVQTEFNAQAGDKRISLADLIVLAGGVGVEQAAKRAGIVVEVPFVPGRTDALQEQTDVSSFAPLEPFADGFRNYVKGDEVVPSEHLLIDRAQLLTLTAPEMTVLIGGLRVLGANVGGVKHGVFTDRLGTLSNDFFINLLDMGTEWAPVSKERHVFEGRDRRTGVLKWTGTRVDLVFGSNALLRALAEFYAAVDAQEKFVRDFVAAWSKVMHLDRFDLV
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PTRD1_BOVIN
Sequence: MHRGVGPAFQLSRKMAASGGEPQILVQYLVLRKDLTQPPFSWPAGAVVAQACHAATAALHLHRDHPHTAAYLRELERMRKVVLEAPDETTLKLLAETLQQKNIDHKLWMEQPENIPTCIALRPYPKEEVSQYLKKFRLFK
What are the official names of this protein?
Putative peptidyl-tRNA hydrolase PTRHD1, Peptidyl-tRNA hydrolase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family. PTRHD1 subfamily.
Protein: DCTA_BURPS
Sequence: MKKPFYKVLYVQVIFAIVVGVILGHYYPSLAVDMKPLGDGFIKLIKMVIGPIIFCTVVTGIAGMQDMKKVGRVGGKALLYFEIVSTCALVLGLAATHILRPGVGFNIDPATLNGKEVASYAAKAHGQSSVDFLMHIIPNTMIDAFAQGEILQILLIALLFGSVLAHLGERGRVVTDFIDGITRVLFGIVHIVTKLAPIGAFGAMAFTIGKYGVGSLVPLLKLIGTFYLTSVVFVLVVLGAIARFTGFSIIRFVGYIKEELLIVLGTSSSEAALPQLMEKLEKAGCSRSVVGLVVPTGYSFNLDGTNIYMTMAVLFIAQATNIELTWMQQLTLLAVAMLTSKGASGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEKELDRAKLRAALSGNGEAAAGEAARV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METE_BACC2
Sequence: MAIQTSNLGYPRIGLQREWKKTLEAFWSNKIDEEQFLTTMKEIRLQHVKVQQEKGIELIPIGDFTYYDHVLDTAYMLGFIPSRFSEFTSYLDVYFAMARGSKDHVASEMTKWFNTNYHYIVPEYEEGLQISLKDNRPLRLYEEAKQELGVDGKPVILGPYTFLKLAKGYTQEQFATILKQLVAPYVQLLSELHAAGAQVIQVDEPIFASLTKEEVQQAKEIYEAIRKEVPNANLLLQTYFDSVEENYEEIITFPVSGIGLDFVHGKEGNLHAISKYGFPADKTLAVGCIDGRNIWRADLDEVLTLFTTLQKQVQTKDFIVQPSCSLLHTPIDKTEETHLSTELFDALAFANQKLEELVLIHSALTKGTESISNELETYRNVHHTIRSSAVRNREDVKAARTALKEEDFSRPLPFEKRYELQQVALELPLLPTTTIGSFPQTTEVRQTRKEWRNGVISNEQYEKFIEKETEKWIRYQEEIGLDVLVHGEFERTDMVEYFGERLAGFSFTKNGWVQSYGSRCVKPPVIYGDVAFINGMTIKETVYAQSLTEKVVKGMLTGPVTILNWSFVRNDIPRKEVSYQIALALRHEIELLESSGIRVIQVDEPALREGMPLKEKDWDAYITWAVQSFLLATSSVANETQIHTHMCYSNFEDIVDAIRALDADVISIETSRSHGEFIDTLKHTTYEKGIGLGVYDIHSPRVPSKDEMYKIVEQSLEVCDPKYFWINPDCGLKTRRTEEVIPALEHMVQAAKDARSLLKTNA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: BPOA2_KITAU
Sequence: MPFITVGQENSTSIDLYYEDHGTGQPVVLIHGFPLSGHSWERQSAALLDAGYRVITYDRRGFGQSSQPTTGYDYDTFAADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYGTARIAKVAFLASLEPFLLKTDDNPDGAAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISEEAVRNSWNTAASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSAEYVEVEGAPHGLLWTHAEEVNTALLAFLAK
What is the function of this protein?
May be a chlorinating enzyme involved in 7-chlorotetracycline biosynthesis.
What are the official names of this protein?
Non-haem bromoperoxidase BPO-A2, BPO2, Bromide peroxidase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Bacterial non-heme haloperoxidase / perhydrolase family.
Protein: RL36_BRUAB
Sequence: MKIKNSLKALKARHRDCQLVRRKGRVYIINKTAPRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HEM1_WOLSU
Sequence: MHYLIVSYSHKNTDIATRERLAFDNGVRSESFLRELVANKFINEGILLSTCNRVEFILSVKEAHKAGDFLMEKLSEYSKIPKEELSERADVYEDTGAIHHLFCVCSSLDSLVVGETQIAGQLKSAFKFAYDGGFCSQKLSRAMHFAFKCAASVRNCTEISKNPVSVASASVSKAKDILGDLGGDTAIVVGLGEMSQLTIKHLTALGCNVILVNRDKAKAEAFAKEFGGMVSVEGFPRLGELLNHHKMLFSATGAPHTVISKDMVEPKSFRRYWFDLAVPRDIEAFESETIRIFAVDDLQEIVNKNLSLREEQAKRAYGIIGRFTQEFYKWLQSLSVDPIIKAMREQAKEAALKEITKAISKGYLPKECEKSVEKIIHNSFNTFLHHPTIKLKEISEEPQSDTVVEAVKLLFGIQEDGLMLDRYKCEYDTTSKEREE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ISPE_RHIME
Sequence: MQAGGIPGFALTFAAPAKINLALHVVGQRADGHHLLESLVTFAECGDRVGLIAADRDRFTVSGRFATDLSAEGNGGNLVLRARDLLRRELAAQGRMAGPVHLHLEKNLPIASGIGGGSADAAATLRGLLSLWGATVEAASLNSLALQLGADVPMCLDRGPLVARGIGEEITPLPDLPPFDVVLVNPLVAVSTPVIFRSLVRKTNPPLVLPEDARSTAEWLTAMAAMRNDLEPPARAHEPMIETVSNALRDAGAALVRMSGSGATCFGLFTGMKSAERAAETISAGHPRWYVQATRTAGKSG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TRIM5_PAPAN
Sequence: MASGILLNVKEEVTCPICLELLTEPLSLPCGHSFCQACITANHRKSMLYKEGERSCPVCRISYQPENIQPNRHVANIVEKLREVKLSPEEGLKVDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEEVAQEYHVKLQTALEMLRQKQQEAEKLEADIREEKASWKIQIDYDKTNVSADFEQLREILDWEESNELQNLEKEEEDILKSLTKSETEMVQQTQYMRELISDLEHRLQGSMMELLQGVDGIIKRIENMTLKKPKTFHKNQRRVFRAPDLKGMLDMFRELTDVRRYWVDVTLAPNNISHAVIAEDKRQVSSRNPQITYQAPGTLFSFPSLTNFNYCTGVLGSQSITSGKHYWEVDVSKKSAWILGVCAGFQPDAMYNIEQNENYQPKYGYWVIGLQEGVKYSVFQDGSSHTPFAPFIVPLSVIICPDRVGVFVDYEACTVSFFNITNHGFLIYKFSQCSFSKPVFPYLNPRKCTVPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2.
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: PSAJ_PICRU
Sequence: MQDLKTYLSTAPVLAISSFIFLAGLLIEINRFFPDALTFAFF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS20_PHOPR
Sequence: MANIKSAKKRAITSEKRRQHNASRRSMMRTFFKKVIAAIEAGEKENATKAFADMQPVLDRMATKGLIHKNKAARQKARLTAKIKAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MURA_WOLWR
Sequence: MHKILIRNNYKPLVGKIKINGSKNAVLPIMAASLLSSSPVILHNVPDLIDVHLMSKLLESLGAEVNFMHNKNYKANHTLKIDCSNINNHVMPYKTASKLRTSFLILGPMLSRFGKARTAFPGGCNIGKRPVDMHIKALEEMGAKIEIDGYNIIATVKGKLQGKEITFEKISVGATENVIMAATFAEGVTTINNAATEPEVLDLIDFLKKMGADIEIDNTKVVITGVEALNGCVHKIIPDRIEAGTYALAAIITGGKLELEGINLSDIRCITNELETIGAMVELYDGGIVISRKNGSIKSANVATDPYPNFPSDMQPQLMSAMCIADGISVIEENIFENRFTHADELRKLGANISIEKSKATISGIKSLSGANLYATDLRSTAALVLASLVAGGETIINNSHHLWRGYEAMHEKLNSCGADISISS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAA35_YEAST
Sequence: MEVDSILGSLSITDDFDQLVDVTSLFDELCSKLKPEAIVKDPRFDLFEGTHSLEVNNSKLDSSLIELTAEEIEFDVNVAYDPPLASVAAIADRLLRCVISWLNDYQTLPTTVLSCRYTESLLSSLVKGTTAGSSWCTGNILYDKVLGSCILGVCYLTKFVQKLLSAGIVFEEEDLNFNNMGFNTFDNLPGQDVVINSLTESLQILEAYSDDSLHLTMLKHILKIIICLVHLEDHLTDYSTKTSHLDELIENANSVNGIFPQLQLSPPKGAFSTYIQKHRSNQFPPRKITKLPTDYSGFITLANDVKTILLVDKAESALETYQFAKFFNKLEQRHVIARILFPLFFIRDDRTVLGKFSYTQFYLLHVKEFSAQTPSEFESSIGNELIQESSNMLLEWYQNCSQNTCRYRQGFNRQLILWDSLQAQFESVNSQVYCSWTYFMKLSSMIEFSLKGFDLDIYKPFEAYSMFWYVYYLSHHLETFLKDSQNDIESNINAIHSMNKKLKKLKAGEKKDQLRLKYRFAMDNEMEQLQATKQFLNYLLKEINITKSLCLIEVFQFAILKSFGLIDNKNSTPSKFSNERLIHNLRFKPFNSIGVPELPEYEVFQQTLKDFVIEEKGAAFDIKLERATNFIETEVRNVVSSIDEIMQGIKGGDNNGVLVTGTRLVQELSLEYYCKLKHTSKALSVNSKVIVNTLKKNIKNKDSHEYKVELVHTTEGWNYFPIQTLRIKQDRYK
What is the function of this protein?
Component of the NatC N-terminal acetyltransferase, which catalyzes acetylation of the N-terminus Met of L-A virus Gag protein.  MAK10 has a role in the propagation of L-A and M viruses, perhaps in the viral assembly.  It is apparently directly needed for optimum respiration.
What are the official names of this protein?
N-alpha-acetyltransferase 35, NatC auxiliary subunit, Glucose repressible protein MAK10, L-A virus GAG protein N-acetyltransferase subunit MAK10, Maintenance of killer protein 10, N-terminal acetyltransferase C complex subunit MAK10, NatC complex subunit MAK10.
What is the protein family that this protein belongs to?
Belongs to the MAK10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_TRIEI
Sequence: MSHPLVPQIIKFATPIAKSLGLELVGAVFHTNQHPPILRLDIRHPHQDTGLDDCERMSNAIGEQLDAANIIPEPYLLEISSPGISKFLDNDRDFIAFKGFNVAVNTSEPYKGKNYWIGQLVSRDQTAVYINQKGRQASIPRSLINTVELQEGR
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYNC_ASPTE
Sequence: MVRLTVLAGFLLTSAACSACVIGERQAASSINNAFKAKGKKYFGTCGDQGTLSDSTNSAIVKADFGQLTPENSMKWDATEPNRGQFSFGGADYLVNYAASNGKMIRGHTLVWHSQLPGWVQGITDKNTLTSVLKNHITTVMQRYKGKVYAWDVVNEIFNEDGSLRKSVFYNVLGEDFVRIAFETARSVDPQAKLYINDYNLDNANYAKTKGMADHVRKWISQGIPIDGIGSQTHLGSGGSWTVKDALNTLASSGVSEVAITELDIAGASSTDYVNVVNACLSVSKCVGITVWGVSDKYSWRSNDKPLLFDSNFQPKAAYNAIISAL
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase C, Xylanase C, 1,4-beta-D-xylan xylanohydrolase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GFPT1_HUMAN
Sequence: MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRWGSQGERGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE
What is the function of this protein?
Controls the flux of glucose into the hexosamine pathway.  Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.  Regulates the circadian expression of clock genes BMAL1 and CRY1 (By similarity).  Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling (PubMed:26887390).
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, D-fructose-6-phosphate amidotransferase 1, Glutamine:fructose-6-phosphate amidotransferase 1, GFAT 1, GFAT1, Hexosephosphate aminotransferase 1.
Protein: LIPA_PHOLL
Sequence: MSKPIQMERGVKYRDADKMALIPVKTVMTERTEILRKPEWMKIKLPADSSRIQGIKSAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPMAPDTNEPVKLAQTIKDMALRYVVITSVDRDDLRDGGAQHFADCISAIREKNPSIKIETLVPDFRGRMDRALEILTATPPDVFNHNLENVPRVYRQVRPGANYEWSLKLLEKFKEAHPDIPTKSGLMVGLGETNEEILDVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPQEFDEMKEEALAMGFTHAACGPFVRSSYHADLQAKGEEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.