PharMolix/UniProtQA huggingface dataset:
Protein: TAT_HV1MN
Sequence: MEPVDPRLEPWKHPGSQPKTACTTCYCKKCCFHCQVCFTKKALGISYGRKKRRQRRRAPEDSQTHQVSLPKQPAPQFRGDPTGPKESKKKVERETETHPVD
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: Y570_HAEIN
Sequence: MAGVRAVQKEKTRRALVDAAFNQLSAEKSFSNLSLREVAREAGIAPTSFYRHFSDMDELGLEMVDEAGLMLRQLMRQARKRIDAGGSVISVSVDTFFEFITNSTNVFRLLLRESSGTSQAFRTAAAREIKHFVDELAEYISYKHQYSQYVAYVQAEGIVTIVFTAGANALDMSKAEREQLKARVILQLRMLAKGADFAANKERGK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator HI_0570.
Protein: COAD_METAC
Sequence: MPKVAVGGTFQYLHDGHARLIEKAFEIAGDGKVYIGLTSDEMLQKNHSIDNYENRRVRLLEYIDEMEIPKEKYEITRLNDPCGPTVEEDFDYIVVSPETYPVALKINRIREKKGKNPLEIVYVEYVMAEDGTPISSTRIAKGEIDRHGKMKRESQA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGDG_SCHPO
Sequence: MKRIRNACELCRRKKLRCNGELTCQNCMVYGEECRYVKRVKHDNRAAVQENERYPILYTPLSTSDHDNDEENEINELKNAVKALDKRFDNFELKLEALFSLLRSQQDSERKVKPGGFPSLVSQILSAGALVDSKLQAYTMRTNFFSNGFSSNDLFPHSFPTWKSAFRDVPDKDWAKTCLDWYFRFINCNWPIFYKKQYMESFEKLYIDKNLVKGAWIVSFYAILALAVSRDKRVDNSKLAESFFATSWFLIQRPGFFLTPQLEKIQALVIMIQFASHLSLYNLCKKLCGQVCLMVKDLNLHKESTDKDLDQDMAELHRRIFWVCYIFETTTSLIFGTPPVLGDLEIECKYPDINYAHCFAENVQGDLIFTCEISLTVLKHEIRTKLYNSNNVFLDKGQKGVISNIQTKILNFERAIPSEMKHYFEILKAGNGLPEELDIIKQHFFTACVEIYLSYCNTLIYLYLADDSIEGSKICLSTARAAIDVIKGFLVVLDPISKNICYLWLFLYCPFTPFLTVFSHLLEDDDLDADICVKDVDRLYSIHAFFLKMKDISGEFAERLSVITENFIQSAEQYLALQNTSVFGTFDALSESFSI
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein C1773.16c.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: ETFA_CAEEL
Sequence: MLSARTVLSRAGLISNASRLNSTLVVAEHDETKLAPITLNAITAASKLGNEVSVLVTGANATKVAEQVAKVNGVKRVLVAQDEKLKNNLPERVAPVILASQKQFNFTAITAGSSAFGRGVIPRVAAKLDVSSISDVTEVHSADSFTRTLYAGNAVKKVKSTAPIKLLTFRGTSFEPAKEGGSGAVENAPSADIKTDLSEFLGQELSKSERPDLATAKVVVSGGRGLKSGDNFKLIYDLADKLGAGVGASRAAVDAGYVPNDMQVGQTGKIVAPELYIAIGISGAIQHLAGMKDSKVIVAINKDPDAPIFQVADIGLKADLFKAVPELTAALP
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Probable electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SEPF_STAAR
Sequence: MSHLALKDLFSGFFVIDDEEEVEVPDKQQQVNEAPAKEQSQQTTKQNAIKSVPQKSASRYTTTSEERNNRMSNYSKNNSRNVVTMNNATPNNASQESSKMCLFEPRVFSDTQDIADELKNRRATLVNLQRIDKVSAKRIIDFLSGTVYAIGGDIQRVGTDIFLCTPDNVEVAGSITDHIENVEHSFD
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: SYK_CAUSK
Sequence: MFQGLSPLARDARAWPFEQARVLLARILRLRLSDAERDLASVLIHSGKADEAVRTFPALAKPVILETGYGPSGLPHLGTFGEVARTTMVRNAFRALTDDAIKTRLIAFSDDMDGLRKVPDNIENKQPLIEDLGKPLTVVRDPFGTHDSFGAHNNARLRAFLDGFGFEYEFVSSTDCYKGGLFDETLLTALARFDAIQKVMLPTLGEERRASYSPFLPISPSTGKVLQVPTLERDVDKGTIVFQDEDGSKVEVPVTGGHVKMQWKPDWAMRWTALGVDYEMSGKDLIDSVKASGQICKALGGVPPEGFNYELFLDENSQKISKSKGNGLSMEDWLRYGAPESLSYYMFQSPKSAKKLYFDVIPKATDEYLQQLDAYPKQEPAKQLDNPVWHVHSGRPPQYGSPVSFSLMLNLVSAANASDKEILWGFLSRYIPGATPQSQPLLDRLAGYAINYYEDFVKPSKVFRAPDDKERAAMLDLLGRLKALPSDCQDAELIQNEVFAVGKDHGFDPLRAWFQALYEVLLGQSQGPRFGSFAAIFGLDRTTALIAEKLAV
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_SALNS
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: NRAM_I61A0
Sequence: MNPNQKIITIGVVNTTLSTIALLIGVGNLIFNTVIHEKIGDHQTVVYPTITAPVVPNCSDTIITYNNTVINNITTTIITEAERHFKPSLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICVAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYAGKMTDSIKSWRRDILRTQESECQCIDGTCVVAVTDGPAANSADHRVYWIREGKVIKYENVPKTKIQHLEECSCYVDTDVYCVCRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTVSCDSPSNVNGGPGVKGFGFKTGDDVWLGRTVSTNGRSGFEIIKVTEGWINSPNHAKSVTQTLVSNNDWSGYSGSFIVENNGCFQPCFYIELIRGRTNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: SOX18_HUMAN
Sequence: MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLPGLAPPQPPPEPFPAASGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAPLAEALRTAPPAAPLAGLYYGTLGTPGPYPGPLSPPPEAPPLESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG
What is the function of this protein?
Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis.  Activates transcription of PROX1 and other genes coding for lymphatic endothelial markers.  Plays an essential role in triggering the differentiation of lymph vessels, but is not required for the maintenance of differentiated lymphatic endothelial cells.  Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX17.  Interaction with MEF2C enhances transcriptional activation.  Besides, required for normal hair development.
What are the official names of this protein?
Transcription factor SOX-18.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYP_RHOP2
Sequence: MRLSRFFLPILKENPKEAEIVSHRLMLRAGMLRQEAAGIYAWLPLGHRVLKKIEQIVREEQNRAGAIELLMPTLQLADLWRESGRYDAYGPEMLRISDRHKRELLYGPTNEEMITEIFRAYVKSYKSLPLNLYHIQWKFRDEQRPRFGVMRGREFLMKDAYSFDVDEAAARKSYNRMFVAYLRTFARMGLKAIPMRAETGPIGGDLSHEFIVLAETGESGVYCDRDVLSLPVPDETVDYDGDLTPIIKQWTSVYAATEDVHDAVRYESEVPEANRLHTRGIEVGQIFYFGTKYSDSMKANVAGPDGTDAPIHGGSYGVGVSRLVGAIIEACHDDNGIIWPEEVAPFRVAILNLKQGDAATDAACEQLYKELAAKGVDVLYDDTDQRAGAKFATADLIGIPWQVLVGPKGLADGKIELKRRSDGSRENIALAETVARLAP
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_BUCAI
Sequence: MSEMTPPQIVSELDKFIIGQEKAKRAVSIALRNRWRRMQLNSELRYEVTPKNILMIGPTGVGKTEIARRLAKLADSPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAIKMIRIKNIKKNKVRVEEIVEEKILDVLVPTPKKNWTESEKNESLAKTIQTFRKKLREGVLDEKEIEINILSTTMGVEIMAPPGMEELTNQLQSLFQNLGGHKKSSRRLKIKDAIVLLTEEEAAKLINQEEIKKEAINAVEQNGIVFIDEIDKICRRGDSSGPDISREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQTSTPSDLIPELQGRLPIKVELQALTIDDFEKILTEPTASITAQYKALMETEGVYINFTKEGIRNIAEAAWKVNESIENIGARRLHTVLEKLMEDISFNASDNKGNTIEINSNYVEEHLDQLTSNEDLGRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_THET2
Sequence: MLTLPDFPLPDARGRFGPYGGRYVPETLIPALEELEAAYREAKKDPAFLEELDHYLRQFAGRPTPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLARRMGKRRVIAETGAGQHGVSVATVAALFGLECVVYMGEEDVRRQALNVFRMKLLGAEVRPVAAGSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLELFGRLPDALIAAVGGGSNAIGLFAPFAYLPEGRPKLIGVEAAGEGLSTGRHAASIGAGKRGVLHGSYMYLLYDHDGQITPAHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGFKLLARLEGIIPALESAHAIAYAAKVVPEMDKDQVVVINLSGRGDKDVTEVMRLLGGEL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ATP23_ASHGO
Sequence: MSKEPNFPPSEKLEKVEAPADLRSIAGFEWWRRTFEYKTGLGLTPEAKVQYEKDYQYVLQREQCKQCYDNRDWLLKYSPTVVFMTQQIAKLNRRRTGDDSLHFDTSKIICDVCPEWKSGGFNPSLGILLCQNRIRDKWQMEDTLSHELVHQFDELKFEVDWMNLKHHACSEVRASNLSGECRLSQEFFRRGFNGSFGRGHQECVRRRAVLSVMGNPKCKDKAEAEQIVDEVWQSCFNDTRPFEEIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: LEUC_BIFLS
Sequence: MGTTLAEKVWADHLVRKGSDGAPDLLYIDLMLMHEVTSPQAFEGLRLAGRKPRHVDQLIATEDHNTPTVDIDRPNPDKTSALQLTTLEKNCKEFGVRLHPLGDADQGIVHAFAPILGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVMATQTLSLKPFKTMAINVEGKLPADATAKDIILAIIAKIGTGGGQGYVIEYRGEAIRNLTMDERMTVCNMSIEAGARAGMIAPDETTFEYLKGRPHAPEGELWDQAVAYWKTLKTDDDAVFDKVVDIDASTLGPYVTWGTNPGQGLPITASVPEPDKIADATKRAAAERAITYMGLKPGMPIKDIAVDTVFIGSCTNGRIDDLRQAAAIMKGHHKAENIHRVLVVPASSRVRLQAEKEGLDKVFEDFGAEWRNAGCSMCLGMNPDKLVPNERSISTSNRNFEGRQGKGSRTHLASPSVAAATAIRGTISSPADL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RUVB_ECODH
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: APGM_METPE
Sequence: MTAHKIVMLVLDGIGDRPCGELAGMTPLQAAKTPILDQLAAEGITGIMDTIGPGIRPGSDTSHLSLLGYPPESYYTGRGPLEAEGCGIHMEHGMIGFRANFATQNDHGLVTDRRAGRIHDTRLLSAAITDQVDLSAFGVTFSFASGAGHRAALALSGEGLGAGVTSNDPKEDGVAPHQVMPVSANPEDQKTAAVCNEFIRQSTAILADHPMNRARVLNGESPASVVLIRGAGEMGGFEPFQQRYDLSGAVIAAATLVTGIGKAVGLEYIPVEGVTGSTTTNLTGKVQTLMATLDTHDFVLLNIKGADEAGHDGHAIEKRDFIERIDAALALLLERNDCIIAVMGDHSTPCPIKEHSADPVPVLIRGDGVRVDLVQAYDEIACAAGGLNRIRGADILWILLDLIDKTHKYGT
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: NU4LC_ORYNI
Sequence: MMFEHVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNFLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SLA2_SCHPO
Sequence: MSSFRLQSDHMQSDASLMTSVRKATSIDETAPKRKHVRSCIIFTWDHHTARPFWTAIKVQPLLANEVQTFKALITIHRVLQEGHKSALVDSQSEKGWLKTCERQYDGESSPKGYSDLIRDYVDYLLDKLSFHAQHPEFNGTFEYKEYISLRQVDDPNEGYETVYDMMNLQDHIDEFQKQLFSNFKRSNKNECRIAALVPLVQESYGIYRFLTSMLRALYSTVDAPETLEPLKHRYKSQHHRLRQFYADCSNLRYLTSLISVPRLPHDPPDLEGDDNIPDLPKRPASIAPQPTGASTIAPQPTGTSPSPPVEMNFPDTSDITPAYSEPEPIQDFWSDPTLDQQLAAQQAAQQAAQQQAELAAQQAAAQQAQLAAQQAAEMERQRMAAQQHQQALEAIQMAQAEQQRIAQEQLAQQQFQMQTQGQLAELEQQLLATRGQLEQSNVLLNQYDARVRTLENELSQAGVNLQEQIHQNDDLIESLKNQILTWKNKYEALAKLYTQLRQEHLDLLSKYKQIQLKASSAQEAIDKKEKMEREMKNKNLELADMILERDRARHELETMHRSQRDKQESTERELRLLQEKAASLERNKSSEVSNLLSRYNTEVAHLEDALHSKDRELANLGVELKSTENRYRQLLQEKEEELEIQKAAVDESLLQLSKLQLDRNDIDQAMDTQIDELLKSQLEKLDDIVDSVLATGIQRLDTSLYELDSPMHAGNQYATPEFILSTIENASNNATDFSTAFNNYFADGPNADHSEVINGVNLFSTAIYEVANNAKGLSRTTGDDQGSDRFVGLSRDLVNMAKRFLSSLFSVNTRKMDVNVKTDLVIGENIELQRYLQQLTQYSEKFLNKESENTVGLLNAPGENIEELVDNQLAETAQAIQQAILRLQNIAAKPKDDSLSPSELQVHDSLLSASIAITEAIARLIKAATASQAEIVAQGRGSSSRGAFYKKHNRWTEGLISAAKAVARATTTLIETADGVVNGTSSFEHLIVACNGVSAATAQLVAASRVKANFASKVQDHLEDAAKAVTEACKALVRQVESVALKAKEVQHEDFSSLGVHEYRRKEIEQQVQILKLENDLVAARRRLFDMRKTSYHVAEE
What is the function of this protein?
Required for cellular morphogenesis and polarization of the cortical cytoskeleton.  Required for establishment of new polarized growth zones where it acts in actin organization.  Involved plasma membrane internalization and is essential for fluid-phase endocytosis.
What are the official names of this protein?
Endocytosis protein end4, SLA2 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SLA2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Localizes at cell ends during interphase and to the medial ring at cell division.
Protein: MTD_METMA
Sequence: MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADFVVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAAAQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
What is the function of this protein?
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
What are the official names of this protein?
F420-dependent methylenetetrahydromethanopterin dehydrogenase, MTD, Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MTD family.
Protein: TBC30_HUMAN
Sequence: MDVLPTGGGRPGLRTELEFRGGGGEARLESQEEETIPAAPPAPRLRGAAERPRRSRDTWDGDEDTEPGEACGGRTSRTASLVSGLLNELYSCTEEEEAAGGGRGAEGRRRRRDSLDSSTEASGSDVVLGGRSGAGDSRVLQELQERPSQRHQMLYLRQKDANELKTILRELKYRIGIQSAKLLRHLKQKDRLLHKVQRNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIHIPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRKSATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR
What is the function of this protein?
GTPase-activating protein (GAP) with broad specificity.  Acts as a GAP for RAB3A.  Also exhibits significant GAP activity toward RAB22A, RAB27A, and RAB35 in vitro.
What are the official names of this protein?
TBC1 domain family member 30.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS18_SALPC
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.