PharMolix/UniProtQA huggingface dataset:
Protein: XERC_STAHJ
Sequence: MEEIQVTFLNMLKVERNFSAHTLKSYHDDLVQFNHFLEQELINLRTFEYKDARNYLSYLYSQNLKRTTVSRKISTLRTFYEFWMTQDETIINPFVQLVHPKKENYLPQFFYEEEMEALFETVAKDTKKGLRDRVILELLYATGIRVSELVNIQLKDIDMSLPGVKVLGKGNKERFVPFGEFCRQSIEQYLREFKPIQHTKHSFLLVNMNGAPITERGVRYVLNDVVKRTAGVTEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGRYTHVSNQQLRKVYLNAHPRAKKESK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_CICAR
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWNITGGTITNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLAGVGCFGFGAFHVTGLFGPGIWVSDPYGLTGRVQSVNPAWGVDGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVGAGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPIFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHVSFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPSTKKPVVS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RF1_METM5
Sequence: MSGNSSTDMYLFKKSLKELKGKKGKGTELISVYVPAGRRLSDISQYLRQELSQSSNIKSKTTMKNVQSAIEVILQRLKLLKEPLEMGVIIFAGMIPRGGPGTEKMEVYVLEPPEPVKTFVYRCDSLFYTDPLEDFIQDTEVYGVILVDRNEATIGTVKGKTITVLKKLTSGVPGKFKAGGQSARRLERLIDDAAHQFMVRIGEYATESFMPILEEKKLKGLLLGGPGNTKNEFAEKDYLHHELKKKIIDTFDLCYTEEFGIRELLDKASDLLRDLDLMKEKNLIQKFFKELIKDDGGLSAYGEAQVMKYLEMGAIDTLIVTEDIGITRVTVKCNNCDYAQEVNVKTNEMFKFEEQLKTKACPTCGGAMYIDEEKDIIEHLSDLCHMHNTDIIVVSTDTEEGSQISRAFKGMAAILRYKL
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SHIDS
Sequence: MHSQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQRVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: C3H9_ARATH
Sequence: MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK
What are the official names of this protein?
Putative zinc finger CCCH domain-containing protein 9, AtC3H9.
Protein: SYC_PROM2
Sequence: MIKLFNTLSKRVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIVWDILRRFLIYSDFKVKYVQNFTDIDDKILKRAKEESSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPKATNHICNICSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNIQEQNINQQGRMANDENSKKLNPQDFALWKKAKDDEPFFDSPWGKGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENEIAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFTTIRELIKSGISPMSLRYFVMTVNYRKPLDFTEEALRSASEAWKNINIALSFMDLTKGAFRYIDKNESIEEEYKEKISFELSQKKLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRVEGFKIDLNEKFFLIENFKTLEKLTKVLGLEKEVLVKESKITEEEISSLINERLKAKKGKNYAKADEIRNLLNEKGIELIDQSKEITTWIRL
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_ALCFA
Sequence: MESIEQRVKKIVAEQLGVAEAEIKA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS7B_CVCBG
Sequence: MKFLIIVLCLSLVNGYGIKRNVQEHDLKDPHEHPTMTWEILERFVGNTLYITTPQVLSLPLGAEVRCDDIEGFSCSWPGYKDYAHDHIDFHFNPSNPFYSFVDTFYVSLGDRVDKIYLRVISATSREKMLNVGCHTSFSVNLPIGIQIYHDKDMKLLVEGRHLECAHRVYFVKYCPYHAHGYCFDDKLKVYDLKRIKSRKAFEKVSQHQKSEL
What are the official names of this protein?
Non-structural protein 7b, ns7b, Accessory protein 7b.
Protein: CU9A_CONCL
Sequence: TFEPNAEECIVDGRCKHRSDWPCEMSSGTTGRCDVSLGACGCSN
What are the official names of this protein?
Conotoxin Cl9a, Cal9.7.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS6_MYXXD
Sequence: MLTRRLVVCLDVKGGRVVKGVQFEGLRDVGDPVELARRYEAEGADELTFLDISASAEERDTLWELVRRTAEQLFIPLAVGGGVRTVDDVGRALRAGADKVSINSAAVANPALLTACAERFGAQCVVASIDAKRDGDRWRVYTHGGRKPTDLDAVAWARECVARGAGEVLLTSIDRDGARTGYDLALTRAVSEAVDVPVIASGGAGSAAHVRAAFQEGGADAALVAGILHDGVTTVGAIKALLRESGLHIRSLT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_CERS1
Sequence: MSEPASISSGIAARYAAAVFELAKDEGALPALEKDMDALGAAWSESADLRDLATSPVYAREEQQKAIAAVAAKMGLSTVTANTLALMGSKRRLFVLPQMVADVQNRIATEKGEITAEVTAAAPLSPEQAARLAATLKARAGKDVKLKTTVDESLIGGLVVKLGSSMIDTSVKARLAALQNAMKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TLDC2_MOUSE
Sequence: MEDTLSGEEGEEEEEEEPAPAPAPQDPVEPQLTEASQVLGASEIKQLSLHLPPRVTGHPWSLVFCTSRDGFSLRRLYRQMEGHSGPVLLLLRDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFSPQLKVFKWTGHNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARREQFCIKELEAWVLS
What are the official names of this protein?
TLD domain-containing protein 2, TBC/LysM-associated domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the OXR1 family.
Protein: COLA1_HUMAN
Sequence: MAHYITFLCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQLSPKKIKGYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWDLWRILTIDGRPQIAVTLNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIENKPLHPVLGILINGQTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPNY
What are the official names of this protein?
Collagen alpha-1(XXI) chain.
What is the protein family that this protein belongs to?
Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cytoplasm. Note=Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.
Protein: RLMH_CAMJD
Sequence: MQVNIFYIQKSDEFKTWSEKYSKLISKYGTLKEINVFNKKIALAQNLNAIEAKKSYEEAFMPYKKGYCIALDERGKDLTSIEFAKLIQDKNELSFFIGGAYGLREEFNQSLDFRLSLSKLTLAHQFVKTLLLEQIYRAFCINNNHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHH_DEVMA
Sequence: YGRRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTVMNHWPGVKLRVTEGWDEDGHHFEESLHYEGRAVDITTSDRDKSKYGTLSRLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.  Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes.  Displays floor plate-inducing activity.  Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes.  In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Sonic hedgehog protein C-product: Secreted, extracellular space. Sonic hedgehog protein N-product: Cell membrane; Lipid-anchor. The C-terminal peptide diffuses from the cell, while the N-product either remains associated with lipid rafts at the cell surface, or forms freely diffusible active multimers with its hydrophobic lipid-modified N- and C-termini buried inside.
Protein: DESA_SPHSK
Sequence: MAKSLQDVLDNAGNAVDFLRNQQTGPNVYPGVPAEYSNWRNEQRAWAKTAVLFNQSYHMVELMVEGPDAFAFLNYLGINSFKNFAPGKAKQWVPVTAEGYVIGDVILFYLAENQFNLVGRAPAIEWAEFHAATGKWNVTLTRDERTALRTDGVRRHYRFQLQGPNAMAILTDAMGQTPPDLKFFNMADIQIAGKTVGALRHGMAGQPGYELYGPWADYEAVHSALVAAGKNHGLALVGGRAYSSNTLESGWVPSPFPGYLFGEGSADFRKWAGENSYGAKCSIGGSYVPESLEGYGLTPWDIGYGIIVKFDHDFIGKEALEKMANEPHLEKVTLALDDEDMLRVMSSYFSDSGRAKYFEFPSAVYSMHPYDSVLVDGKHVGVSTWVGYSSNEGKMLTLAMIDPKYAKPGTEVSLLWGEPNGGTSKPTVEPHEQTEIKAVVAPVPYSAVARTGYADSWRTKKA
What is the function of this protein?
Involved in the catabolism of syringate.  Catalyzes the conversion of syringate to 3-O-methylgallate (3MGA) in the presence of tetrahydrofolate.  Has weak activity with vanillate and 3-O-methylgallate.
What are the official names of this protein?
Syringate O-demethylase, Tetrahydrofolate-dependent syringate O-demethylase, H(4)folate-dependent syringate O-demethylase.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RECO_DEHM1
Sequence: MTKPHDFKTRAIIVRKTKCGEADRILSLLTPDLGLIQGFAKSVRKTKSKLSGHLELFCYSEVSLARGKAIDTVTGSQTIQSFLNIRSSLQLSAMAFYVCELAFHFSPEESANPAIFQLLLSTLEELDNTTQAELCTKYFEIHLLEMSGYKPELRECANCHQKLLATTNYFSPESGGIICPDCRNTQTGIPISVNAVKVLRYIQENDIPNIYRLKINREILSELELAIRANIRFVLEKEPKALLWLDSLSRANL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SSB3_CLOAB
Sequence: MNKVVLIGRLTKDPELKFTPGTGTAVASFTLAVDRRFKKEGQQEADFIPIVVWGKQAESTANYMSKGKLMGVSGRIQTRSYDAKDGTRRYVTEIVAEEVQFLEWGSSNNNSMANDQFNNGNENGSMQLPDNNDITPIDDGDIPF
What are the official names of this protein?
Single-stranded DNA-binding protein 3, SSB 3.
Protein: RL13_HAEIG
Sequence: MKTFVAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVINADKVAVTGRKETDKLYYWHTGYVGGIKQATFKEMIARRPEAVIEIAVKGMLPKGPLGRAMFRKLKVYAGGEHQHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL15_METCA
Sequence: MFLNTIGARDGSRPEKKRVGRGIGSTLGKTCGRGHKGQKARAGGFHKVGFEGGQMPLQRRLPKVGFRSAKKRFVAEVTLTQISKVGGGVIGLAELKEAGLVPTEAKRVKIIATGSVGGVVTVRGVGVTRGARAAIEAAGGKVES
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: CAPSD_TOMS1
Sequence: MSYSITSPSQFVFLSSVWADPIELLNVCTNSLGNQFQTQQARTTVQQQFSEVWKPFPQSTVRFPGDVYKVYRYNAVLDPLITALLGSFDTRNRIIEVENQQSPTTAETLDATRRVDDATVAIRSAINNLVNELVRGTGLYNQNTFESMSGLVWTSAPAS
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ISPE_CYAP4
Sequence: MRAYTLIAPAKINLFLQIIGDHLQQDQPTGYHNLVMVLQSVSLSDELQLRPLSGEARSLRLDPPILLHCDHPQVPLDQTNLVYRAAALMWQKFPGQAGVEITLHKRIPIGAGLAGGSTDAAAVLVGLNLMWELGLTQLELQELGSQLGADVPFCIRGGTSLAVGRGDQLSPLPDLEGIYVVLGKYHDLSVSTPWAYQTYRQQFQASYAQTLEEQEQRRQQGGSGALLKAIAHRDGGQIGQLLHNDLEKVVLPAYPRVEYLRQQFANQSPLGTMMSGSGPTVFALADSAAAAEEIYAGVRGAIADPYLDLWICQLCNQGIQVQPL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RL16_STRP7
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: OPSD_LITMO
Sequence: MNGTEGPYFYVPMVNTSGIVRSPYEYPQYYLVNPAAYAALGAYMFLLILVGFPINFLTLYVTIEHKKLRTPLNYILLNLAVADLFMVFGGFTTTMYTSMHGYFVLGRLGCNIEGFFATLGGEIALWSLVVLAIERWVVVCKPISNFRFGENHAIMGLAFTWLMAMACAAPPLVGWSRYIPEGMQCSCGIDYYTRAEGFNNESFVIYMFVCHFLIPLMVVFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVVIMVIAFLICWCPYAGVAWWIFTHQGSDFGPVFMTIPAFFAKSSSIYNPMIYICLNKQFRHCMITTLCCGKNPFEEEEGASTASKTEASSVSSSSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: TIG_CHLP8
Sequence: MQKNITNVSDTEQQLEIILTAEEYQPEYDQQLEEARRSIKIKGFRQGHVPVGMLKKMIGPSLEAEVAEKMASKHFSAIADEEKINPASRAQIDSFNFGDGELTIKISYEIHPEFELKDLSAYSFTQAEYSVTDEDVEREIKLILKGHGTMVTIEEAAGEGDTLIGDVTKLDADGNAVENGKNENHHFNLEYLPADNPFRMALEGRKAGDSVEVNVEPKEEGGEAIRYRVDVKEVKRLELPELDDELVKEITQQRFENVTDFKADVKLQLQAHFTDKSEQDLLEAMSAKLIEEHPVPTPKAMVASFQNMLLENAKRQMGGQFPKSLNEAEFLETLKPNAEKHARWLLVSQKIAKENELNVTDEDIKAYAEKEAEKEPSLTVEQLVSTYMSTEFKDYIIDTILKEKIYDVIKSKVTITKEATPIPEHQG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL20_PROMS
Sequence: MARVKRGNIARKRRNKILNLAKGFRGGNKNLFRTANQRVMKALCNAYRDRRRRKRDFRRLWISRINASARINGTNYSKLINGMKNADIIINRKMLAQLAITDPKCFEKIVSSVSQ
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: BPPBI_BOTJA
Sequence: QNGPRPIGIPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent (By similarity).
What are the official names of this protein?
Bradykinin-potentiating peptide 11i, BPP-11i.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: TYPH_SHESR
Sequence: MFLAQEIIRKKRNGLALSTEEIQFFVKGITTNAVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLGLNGPVIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIPGYQTEPSSELFRKVVKDVGVAIIGQTGDLVPADKRFYSIRDNTATVESISLITASILSKKLACSLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLTDMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYAVTMGLCAEMLLLGGLATDEADARAKLNRVLDNGRAAEIFGKMVSGLGGPVDFVENYSKYLPQSQIIRPVFADTQGYAHSMDTRELGLAVVTLGGGRRKPGDALDYSVGLTQVCALGDKIDASTPIAVIHAQSEDAFAQAEEAVKKAIRIDEVAPEKTPEIYAYIRAADL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: NSMF_MOUSE
Sequence: MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPAIEGPQPHVYTISREPALLPGSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDISRPCQSWAGSRQGSKECPGCAQLVPGPSSRAFGLEQPPLPEAPGRHKKLERMYSVDGVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACNTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL
What is the function of this protein?
Couples NMDA-sensitive glutamate receptor signaling to the nucleus and triggers long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes.  Part of the cAMP response element-binding protein (CREB) shut-off signaling pathway.  Stimulates outgrowth of olfactory axons and migration of gonadotropin-releasing hormone (GnRH) and luteinizing-hormone-releasing hormone (LHRH) neuronal cells.
What are the official names of this protein?
NMDA receptor synaptonuclear signaling and neuronal migration factor, Juxtasynaptic attractor of caldendrin on dendritic boutons protein, Jacob protein, Nasal embryonic luteinizing hormone-releasing hormone factor, Nasal embryonic LHRH factor.
What is the protein family that this protein belongs to?
Belongs to the NSMF family.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope. Nucleus membrane. Nucleus matrix. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, dendrite. Synapse. Synapse, synaptosome. Postsynaptic density. Membrane. Note=Found on the outside of the luteinizing-hormone- releasing hormone (LHRH) cell membrane and axons projecting from the olfactory pit and epithelium. Associates with transcriptionally active chromatin regions. Detected at the nuclear membranes of CA1 neurons. Cortical cytoskeleton. Localized in proximal apical dendrites. Colocalizes with CABP1 in dendrites and dendritic spines. Myristoylation is a prerequisite for extranuclear localization. Translocates from dendrites to the nucleus during NMDA receptor- dependent long-term potentiation (LTP) induction of synaptic transmission at Schaffer collateral/CA1 synapses of hippocampal primary neurons and in an importin-dependent manner (By similarity).