PharMolix/UniProtQA huggingface dataset:
Protein: IF2_STRA1
Sequence: MSKKRLHEIAKEIGKTSKEVVEQAQSLGLPVKSHASSVEENDATRIVESFSSSKTKAPTNSVQTNQGVKTESKTVETKQGLSDDKPSTQPVAKPKPQSRNFKAEREARAKAEAEKRQHNGDHRKNNRHNDTRSDDRRHQGQKRSNGNRNDNRQGQQNNRNKNDGRYADHKQKPQTRPQQPAGNRIDFKARAAALKAEQNAEYSRHSEQRFREEQEAKRQAAKEQELAKAAALKAQEEAQKAKEKLASKPVAKVKEIVNKVAATPSQTADSRRKKQTRSDKSRQFSNENEDGQKQTKNKKNWNNQNQVRNQRNSNWNHNKKNKKGKTNGAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAHAKVEVDEADIERFFADEDYLNPDNLTERPPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTVEAINHSKAAGVPIIVAINKIDKPGANPERVISELAEHGVISTAWGGESEFVEISAKFGKNIQELLETVLLVAEMEELKADADVRAIGTVIEARLDKGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRVSLENLFDTLKAGEVKSVNVIIKADVQGSVEALAASLLKIDVEGVKVNVVHSAVGAINESDVTLAEASNAVIIGFNVRPTPQARQQADADDVEIRQHSIIYKVIEEVEEAMKGKLDPEYQEKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDGVVIFDGKLASLKHYKDDVKEVGNAQEGGLMIENYNDLKEDDTIEAYIMEEIKRK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_NITEU
Sequence: MALIIGLTGGIGSGKTRAADSFRELGIEIIDTDQIAHELTRSAGKAISPIRIAFGDCFILDDGSLDRSAMRRLVFSDETARHRLESILHPLIYQETLQRLPLIQSEYGIVVVPLLLEIDGYLKLVDRVLVIDCPEPLQISRTMLRSKLSEQEVRDVMAVQCSRDKRLAQADDVIVNDSGEQHLQRQVEELHRKYLMLARKHGL
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_BURO0
Sequence: MQTSLLKPKIIAVESLGENHARVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTLDGVQEDVVNLLLNLKGVVFKLHNRDEVTVTLRKEGEGVVTAGDIELAHDCEVINPNHVIAHLSKGGKLDVQIKIEKGRGYVPGNVRRYGEDTAKIIGRIVLDASFSPVRRVSYAVESARVEQRTDLDKLVMNIETSGVITPEEAIRQSARILVDQLSVFAALEGTETAAEAPSRAPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL7_STAAN
Sequence: MANHEQIIEAIKEMSVLELNDLVKAIEEEFGVTAAAPVAVAGAAGGADAAAEKTEFDVELTSAGSSKIKVVKAVKEATGLGLKDAKELVDGAPKVIKEALPKEEAEKLKEQLEEVGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SDHB_RICPR
Sequence: MVELRLPSNSVVKKGREHKAQQKMLKPRKVKVYRYDPDLDENPTIDSFEIDLSKTGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNIDGTNTLACIKPIEDISGDIKIYPLPHMKVVKDLVPDMSHFYAQYESIEPWLKNDSPAPSNSERLQSIKDREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAILLQAYRWIADSRDDNTGARLEALEDPFKLYRCHTIMNCTKTCPKGLNPAKAIGRVKNLIAERHGV
What are the official names of this protein?
Succinate dehydrogenase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
Protein: SP3D_BACSU
Sequence: MHDYIKERTIKIGKYIVETKKTVRVIAKEFGVSKSTVHKDLTERLPEINPDLANEVKEILDYHKSIRHLRGGEATKLKYKKDEILEGEPVQQS
What is the function of this protein?
This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K).
What are the official names of this protein?
Stage III sporulation protein D, 14 kDa transcription factor.
Protein: GPI13_SCHPO
Sequence: MEEKRVKCKKKLTSTIGTWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFDEINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGDEYLSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYFKAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILANNELHSPFPAEFYVLLPSFYILLNSFNQKLMEYFKGFVKLDYFSIFITFLHVCSFGSNSFTVWEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALAFILLQVISSYVTNCREEQGAFCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLHLRRVLGLSLKLYHLSILYFFELISSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRSKFAKINVIERSYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQLKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPLFSFEPLSKKNRFLINLFRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSGILLVTHQLFVLIQCFGSSVVKFPEDAE
What is the function of this protein?
Involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.  Involved in cell wall biosynthesis (By similarity).
What are the official names of this protein?
GPI ethanolamine phosphate transferase 3, Glycosylphosphatidylinositol-anchor biosynthesis protein 13.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DNAK_HISS2
Sequence: MGKIIGIDLGTTNSCVAVMDGDKPRVIENAEGERTTPSIIAYTNDNETLVGQPAKRQAVTNPKNTLFAIKRLIGRRFEDQEVQRDVAIMPFEITKADNGDAWVSVKGEKMAPPQISAEVLKKMKKTAEDFLGETVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKGKGNQTIAVYDLGGGTFDLSIIEIDEVGGEKTFEVLATNGDTHLGGEDFDNRVINYLVDEFKKEQGVDLRNDPLAMQRLKEAGEKAKIELSSAQQTDVNLPYITADATGPKHLNIKLTRAKLEALVEDLVARSMEPVKVALSDAGLSVSEINDVILVGGQTRMPLVQQKVAEFFGKEPRRDVNPDEAVAIGAAVQGGVLAGDVKDVLLLDVTPLSLGIETMGGVMTTLIEKNTTIPTKKSQVFSTAEDNQSAVTIHVLQGERKQASANKSLGQFNLEGINPAPRGMPQIEVTFDIDADGIIHVSAKDKGTGKEQKITIKASSGLSDEEIQQMVRDAEANAEADRKFEELVQARNQADHLVHSTRKQLAEVGEKLSAEDKAPIESAVNELETAAKGEDKTEIDAKVQALIQVSEKLLQASQQQAQADAGAQQSQSTKGGEDVVDAEFEEVKDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: UVRC_ECOSE
Sequence: MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBP7_CAEBR
Sequence: MARSDGFSPRKSLRRSAREHSRSYVGQGSNDDFDDMYSPPSRRRGSGGGDGNGYTRSGRKIHHSRYYEEDYQDAISSDDERMYRPRRNSNSLTYRQQCKQAIDESKRIQKVPPAKRKRIYMSDDEEEFVETRQMENTAPDRPTRRSSRRMSSTHEEPDVLDQEDVSPIRRTRRTTIRFGSEPVEENMEVPRVLETNDMANEAIVQAVDNTENGETEEDVIEKIGREEEEEGDEEEAESGEKEQVGLLFHRIFNQAYLQEDEESSNAESSEESTAPRQYSLRRRQPVVQFNQSEARENRRARLEHHRAANANRHHRNRNTSNRRRRSGSDSDSDDMVLPRPDKRQSRPHMHNRGERERGRFMPINMTEKELQSAQHILMDRMRKTDAGQGASDIDPMSVDSSVGFDQVGGLSHHIQSLKEVVLFPMLYPEVFAKFKINPPKGVVFYGPPGTGKTLVARALANECRRGANKVAFFMRKGADCLSKWVGESERQLRLLFDQAYAMRPSIIFFDEIDGLAPVRSSKQDQIHASIVSTLLALMDGLDGRGEVVVIGATNRLDSLDPALRRPGRFDRELRFSLPDLNARRHILDIHTSKWEENKPTPETLDGIAEKTSGYCGADLKFLCTESVLIGLRSRYPHIYMCSERLKLDITTIKITEEHFGHAMRRITPASRRDLTIPSRPLDERTSILLGDIVKNLISLRIPQGYRCVENAMATASTELEQVVRALEPNLTVPAIRLLLCGSPSLSDGGQTSYVLPAILAKLDHLPVFSLSVSSLLTDGRPEEAFSNAVQSAMRASATGPCIMLLPSIDEWIKVIPVSVQHMLITCLESMTGFTPILFLSTLDSSFEDAPEYATEVFRHANCISLNPSRRSVRKRYFEFVIDGVRRKPKVFDPTIYEMPQADDDSPEAKPSRKLNDDETRELLKMYTALQRQMRMFFKERLSRLIRDRRFVEFVEPVDPEEAEDYYEIIETPICMQDIMEKLNKCEYNHADKFIADLVLIQSNALEYNPSNTKDGKLIRQMANTFRDAIDDMIDCELDESFVERIEMVSRMLQDAGVTPTSDQLLTEIPKGFSRKKPWTMANTLAKEIEQWKAEREAENEKLKEKLGISTDTAQSAIEENKSEEGTSSSVEEIKKKLNKKKKDQKRNKKASSQDPDGDDTEETEEAVAENNVDADVEMKETPADPVPTIQSSSSQEREIIVSADSITDLIKLCVEKSEGWSVSELERLSSVLSHTIERFRDEWNRENLPEQLAQIVREWEATDATNEKIANGKASNKNGIVFNGY
What is the function of this protein?
Thought to form a complex that enhances transcription from repetitive DNA sequences by modulating chromatin structure.
What are the official names of this protein?
Tat-binding homolog 7, Lin-48 expression abnormal protein 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: ATG12_COCIM
Sequence: MSATPPIPSPGSSKPSSPRSASRNLGLNTRQASRPQIGARRDTNNGSESPAATAPIPDEDHGAELPLTMTASVILTGLPKDAHRALADVEAIDAGKVTVRFHPLPSAPILRNRVFKISASQKFETVVRFLRKKLDCSESDSVFCYVNSVFAPGLDESVGGLWRCFKTDDQLIVSYSMTPAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: TPS6_DICPU
Sequence: MKQHILWDLNNYINQDYTLPKINCTFDIKTNINSSVKEDQEKWILEFFGNSIEKSKKYLGQQTFLIYMFSFPFASPDELKCIFKIMDWAFIIDDFYFESKAKGMSYLEKLFKTNKDKSKDKFIKLFWEIINEYKQIGKKDSIDVLINEIYSWAKSAVQCSKNDQISSNSTLAEYMESRYYDIGIIMALASSTTLISIPKEIRESKIFKQLEYWFVVCNTLINDCYSFNKEKNEPVLTNYVKIKTLQCGSIQTSLDFVAETIENSLTEINNHSNQLIQQYPNNINLKQYIKSLKYLTSGHLHVSSICNRYK
What is the function of this protein?
Terpene synthase that converts its substrate farnesyl diphosphate (FPP) into the sesquiterpenes beta-elemene, (E)-beta-farnesene and (E,E)-alpha-farnesene.
What are the official names of this protein?
Terpene synthase 6.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: YVEB_VACCC
Sequence: MFNFSVSNPINPFSTSSSYLYALYSPLLNKSLNSIFNTFSTNSWDVTHCSTICLMKRVSSSDFPLILYMGFRLYLASIVYLSDSAINILSTCVPIILHLLDLHSLL
What are the official names of this protein?
Uncharacterized 11.9 kDa protein.
Protein: SPED_ECOL5
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTTEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSEDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: ANGS_PASSA
Sequence: YFFSLFLVTIFLYKWLAKKTPSKNLPPSPPRLPIIGNLHQIGPDLHISLRDLARKYGPLMQLQLGRIPVLVVSSAEATREVLKTHDVVFSQRPITSAIDKLCYKGRDVAFSRYSEYWRQVRSTCVTQLLSNSRVHSFHNIREEEVALLIQNIENSASEVINLGEQLIQLTRNVVCRVSVGSEYLSGHKGKLYQKLLAEVTEMLAYTYSIGDFIPLLGWVDWLSGSKAKVEKTAKEVDAFLEGALRDHIKTMASNKGSANDDFLSILLEIREADAGSTLDEECIKAIVWDMILGGTETTSTTLEWIVAAIIKNPDVMFKLQKEVREIGKGKSKIEEVDLVKMNYLKAVMKESMRLYITAFLLPREAKQDVKLMGYDISSGTQVLINTWETARDPSLWDNPEEFRPERFLNSPIDYKGLHYEYLPFGGGRRGCPGIQFAMAVNELAVANVVYKFDFKMPDGERFEDLDMSGVPGISLYRK
What is the function of this protein?
Involved in the biosynthesis of coumarins and furanocoumarins (FCs), natural products required for defense responses against attacks by predators with potential medical and agroindustrial usages such as anticoagulant, rodenticide and artificial vanilla substitutes (PubMed:29971079).  Involved in angular furanocumarin biosynthesis.  Converts (+)-columbianetin to angelicin (PubMed:19098286).  Produces also some hydroxycolumbianetin as a by-product (PubMed:19098286).  No activity with demethylsuberosin, (+)-marmesin, 5-hydroxymarmesin, psoralen, bergaptol, xanthotoxol, bergapten, xanthotoxin, isopimpinellin, cinnamic acid, 4-coumaric acid, 2-coumaric acid, ferulic acid, coumarin, herniarin, scopoletin, or umbelliferone (PubMed:19098286).  The reaction mechanism is initiated by the abstraction of syn-C-3'-hydrogen (PubMed:19098286).
What are the official names of this protein?
Angelicin synthase, Cytochrome P450 CYP71AJ4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.
Protein: GLND_MANSM
Sequence: MIGHNNFIIQSVILRFFMFQSVEGLLTPGLIKQQKEQLKQTELENFAQADVNSLISHRTLFCDNFLIRLWRQFSLHEVTDLALIAVGGYGRREIFPLSDLDFLILTEQPMPADLAKKVEEFIQFVWDCGFDVGASVRTLEDCDSQGRADITIATNLLESRLLTGNETLFDKLSSIVGREDFWPRKTFFEAKIQEKKQRYQRYNNTSYNLEPDIKYNPGGLRDLHLIYWIALRHSNALSLEEILQSGFIYPEEYAELERNQQFLFKVRFALHLILKRYDNRLLFDRQVKVSELLGYQGEGNQGVETMMKAFFQSLQAISLASDILAKHYKEHFVDENGEEECQVLDDNFQMINNAIFLVREDCFVQQPDTILDLFSYLIIRPQAELHSSTLRLLHLALGQLNGYLSELPAAREKFLRLLTQPRGIERALIPMHKYGVLTAYIPEWKGIEGLMQFDLFHIYTVDEHTMRVLAKLETFLSEETAEAHPLCVKLFPSLPDRALIYIAALFHDIAKGRGGNHADLGAVDVGRFAAQHGFDCREIETMKWLVKQHLFMSVTAQRRDIHDPEVVMNFAAEVQNQVRLNYLVCLTVADICATNTTLWNSWKRSLFASLYQYTNQQFNQGMDNLLDNQEQEEQNKALALEILQSQGFTEDVQSLWKRCPGDYFLRNTPKELAWHAVLLAGVETELLVKISNRFSAGGTEVFIYCKDRPNLFLKVVAAIGNKKLSIHDAQIITSLDGYAFDSFIVTELDGSLLKFDRRRVLEKAIINSLNSNELTKLQGSENHKLQHFNVKTEVRFLNTEKTTHTEMELFTLDKAGLLADVSLVFSELNLSIQNAKITTIGEKAQDFFILTNAKGEALSERERQSLSEKLQARLD
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: FRDC_SERP5
Sequence: MTTQRKPYVRTMTPTWWQKLGFYRFYMLREGTSVPAVWFSIVLIYGVFALKGGVDSWAGFVGFLQNPLVLLINFVALLAALLHTKTWFDLAPKAANIVVNSEKMGPGPIVKTLWAVTVVASVVILAVALV
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1358_LEVBA
Sequence: MATWIWILIVIVVGLACAAGGFYGARKYMENYLKDNPPINEDQLRAMMLQMGQKPSQRKLHQMMAAMQQNARKK
What are the official names of this protein?
UPF0154 protein LVIS_1358.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NADB_PYRAB
Sequence: MIDMEVGIVGGGLAGLVAAISLVEKGVDVSIIGPKSKDSNSYLAQAGIAFPLVEGDSIRIHVLDTIRAGKYINDEEVVWNVISKSTEAYSFLVSHGVTFTGNELEGGHSHPRVFTIKSETGKHVIPILEKHARELGVNFVRGFVEEIGIKNGKLAGVFLNGELLKFDAVVVATGGFSGLYRFTAGVKENIGLLIGDLALKGVPLRDMEFVQFHPTGFIGRRTYLITEAVRGAGAKLVTGDGERFVNELETRDVVARAIYLKMLEGKGVFLDARGIEDFKDRFPYVYSVLKKEGIDPGKDLIPVTPVAHYTMGGISVDIFYRTRIRGLYAIGEAASNGFHGANRLASNSLLECVVSGLEVARTILREEPKRGANDAPYNFDELGDVDSIREIMWNHAGIVRDKSSLLEGLKKLEGVEADQRLKVVAKAVLTLALEREESRGSHYRRDFPFMRKEFERPSFFHLNV
What is the function of this protein?
Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
What are the official names of this protein?
L-aspartate oxidase, LASPO, Quinolinate synthase B.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XRN2_USTMA
Sequence: MGVPALFRWLSKKYPRIVSSVQEEDPKTAPGPDGTEITLPLDTSTPNPNGEEFDCLYLDMNGIVHPCTHPEGKPAPETEEEMMVEVFAYTERVVNMVRPRRLLMMAIDGVAPRAKMNQQRSRRFRAAKEAREKHEEEQAALAEWKAKGLGATDDEKKSKRAWDSNAITPGTPFMDLLAASLRYWVAQKINSDPGWKDIQVIISDASVPGEGEHKIMEHIRRQRSHPEHDPNTKHVIYGLDADLIMLSLATHEPYFKVLREDVFAADNKPKTCNLCGQPGHFAASCTGAAKKKSGQHDEIAPTPPEKKPFIFLDVATLREYLEVELNIPQLPFAFDLERAIDDWVFLIFFVGNDFLPHLPSLEIRDGAIDTLLRIWKKELPAMGGYLTNHGRVELGRAQLILSGLASEEDEIFRRRKEDEDRRETNRKRREEMQQRRDKELDQGNFGNGSMVEVMSKKRRAHETEKPAFNGVSAQEARDQANSSNKSYDPRKKAIVLGGDNNQVVSDRNAARQANMDAAEALKAELMGDAPKQQEADAERALKKVKTEAGAEPTTASVEKQEHGDDQDSASAGTKRKADQVQHHANAGDDDVAKIEAATEDGDADADTDANADANADAEVDAEAEDDEEEDNDEVDGNEDVDPVTTIKKRKVNADGTVDYEDTVKMWEPGYRERYYKEKFGVDLSDTDFRRSVVKSYIEGLCWVLAYYYQGVPSWQWYYPFHFSPFAADFEDLESLDIQFQLGSPFKPFEQLMGVLPADSRASIPPAFHPLMTESDSDIIDFYPSEFEIDMNGKKMAWQGVALLPFIDEKRLLDALKERYPLLSEDEVRRNGFGNNTLFVGNESRLYDFLCEEIYAKKRTTDDGETPKRVAVNPALSGGITGFVKPDPVCVPGSTFNSPLTSQALHDIHNDRSISVLYDFPEQKTPHRSVLLKGLKPPKRILSAAEIDWVKRGSPDNRGRGRGRGAHHGGAGRDFHRSSNGQQHNNNGYAGGENGSAGYRGSNGGGYGSHNGGGGGGYGAPVGRSHDYQQYSQSGSGGGGGGYGNYGGYGGYGGSGYGVGGRDGGAYYGGYGGGGGGAYGAAPTYASAGAYDAYAGYGGSGGYGAYGASAYAPGAGGNRDNRYAAYTQPSMHVGPAAGRGGRQAAPANHAGYAGLPSLGAPPAPPAPPTHPAAAYGGYTNGGYGGYGAPAHGYGGAPPARGGGRGGRGAGSRGAGRGANNASYAGRGGAYGSFY
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity.  Required for the processing of nuclear mRNA and rRNA precursors.  May promote termination of transcription by RNA polymerase II (By similarity).
What are the official names of this protein?
5'-3' exoribonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLA_LACLA
Sequence: MDVTWTVKYITEFVGTALLIIMGNGAVANVELKGTKAHAQSWMIIGWGYGLGVMLPAVAFGNITSQINPAFTLGLAASGLFPWAHVAQYIIAQVLGAMFGQLLIVMVYRPYYLKTQNPNAILGTFSTIDNVDDNDKKTRLGATINGFLNEFVGSFVLFFGAVAATNIFFGSQSITWMTNYLKGQGADVSSSDIMNQIWVQASGASASKMVAHLFLGFLVMGLVVALGGPTGPGLNPARDFGPRLVHSLLPKSVLGEAKGSSKWWYAWVPVLAPILASLAAVALFKMIYL
What is the function of this protein?
Mixed channel protein that transports both water and glycerol.
What are the official names of this protein?
Glycerol facilitator-aquaporin gla, Aquaglyceroporin, Glyceroaquaporin.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IGK_HUMAN
Sequence: DIQMTQSPSTLSASVGDRVTITCRASQSINTWLAWYQQKPGKAPKLLMYKASSLESGVPSRFIGSGSGTEFTLTISSLQPDDFATYYCQQYNSDSKMFGQGTKVEVKGTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
What is the function of this protein?
Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa light chain, Immunoglobulin kappa light chain EU.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: SECA_NEIMF
Sequence: MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQAKTAEFKQRLADGQTLDGILPEAFAVCREASRRTLGMRHFDVQLIGGMVLHDGKIAEMRTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISDMQPFDRQNAYAADITYGTNNEFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDEARTPLIISGQADDNIQLYQIMNTVPPHLVRQETEEGEGDYWVDEKAHQVILSEAGHEHAEQILTQMGLLAENDSLYSAANIALMHHLMAALRAHSLFHKDQHYVIQDGEIVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVEIKRENQTLASITFQNYFRLYTKLSGMTGTADTEAFEFQSIYNLETVIIPTNRPVQRKDFNDQIFRSAEEKFEAVVKDIEECHKRGQPVLVGTTSIENSELVSHLLQKAGLPHNVLNAKEHEREALIVAQAGKVGAITVATNMAGRGTDIVLGGNLKHQTDAIRADETLSDEEKQAQIAALEDGWQAEHDKVMEAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLFALDRAAAILNRLAPERGVAIEHNLLTRQIEGAQRKVEGRNFDMRKQVLEYDDVANEQRKVIYSQRNEILTSKDISDLMQEIRSDVVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLHEDIQSWLKADNAIDGQDIKERLIERIENEYAAKTELVGKQAMADFERNVMLQVIDNQWREHLAAMDYLRQGIHLRSYAQKNPKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAVVEEQPIGNIQSIHSESPDMEELLGQSQTDLVTEAFNPDGTDFSPEALEARGQIVHRNDPCPCGSGLKYKQCHGKLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.