PharMolix/UniProtQA huggingface dataset:
Protein: FUMC_LISMO
Sequence: MERIERDTLGEISVDATKYWGAQTERSKRNFAIGDNPMPIEIIYAFAQLKKATAKVNAAEGKLAEEKAIAIGQVCDQIIQGELDEHFPLVVWQTGSGTQSNMNVNEVIAHVANLTLGEGQIHPNDDVNMSQSSNDTFPTAMHIAAYGALVTKLLPEITKMEAVLTEKKNKYMHLVKIGRTHLQDATPLTLGQEISGWEACLTNNKNYLETSMKAILPLAIGGTAVGTGLNASRDFGDKVAEELMKQTGYPFTSDSNKYFALTSHSPINFVHGAIRSLASDLMKIANDIRLLASGPRSGIGELEIPANEPGSSIMPGKVNPTQCEAITMVAAQVMGNDVTINVAASQGNFELNVYKPVIIFNFLESIKLLADSMRSFRVHCLEGLTANEKVIETKVNDSLMLVTALNPHIGYEKAAKIAKLAFDENTTLKEAAIKTGFVTEKEFDLWINPLKMTNL
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCB_RAT
Sequence: MAEDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDSGFGAPAASQVASAQPGLASGGGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
What are the official names of this protein?
Clathrin light chain B, Lcb.
What is the protein family that this protein belongs to?
Belongs to the clathrin light chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Protein: GSA2_BACCZ
Sequence: MKKFDKSIAAFEEAQDLMPGGVNSPVRAFKSVGMNPLFMERGKGSKVYDIDGNEYIDYVLSWGPLIHGHANDRVVEALKAVAERGTSFGAPTEIENKLAKLVIERVPSIEIVRMVNSGTEATMSALRLARGYTGRNKILKFIGCYHGHGDSLLIKAGSGVATLGLPDSPGVPEGVAKNTITVAYNDLESVKYAFEQFGDDIACVIVEPVAGNMGVVPPQPGFLEGLREVTEQNGALLIFDEVMTGFRVAYNCGQGYYGVTPDLTCLGKVIGGGLPVGAYGGKAEIMRQVAPSGPIYQAGTLSGNPLAMAAGYETLVQLTPESYVEFERKAEMLEAGLRKAAEKHGIPHHINRAGSMIGIFFTDEPVINYDAAKSSNLQFFAAYYREMVEQGVFLPPSQFEGLFLSTAHSDADIEATIAAAEIAMSKLKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_AQUAE
Sequence: MLRKKTLRDVDVKGKRVLVRVDYNVPLDEQGNIVDDTRIRASLPTVEYLLDANAKVILMSHLGRPKNRDPKYSLAPVAKRLSRYINKEVKLAPDCVGEEVKRIVNSMKEGDVVLLENLRFHKEETECDENFARELASLGEVYVADAFGTCHRKHASVYLVPKFLKPAVMGFLLEKEITYFEKAMVAPQRPVVAILGGAKVSSKLEVIKNLIRRVDKLFIGGAMAFTFLKAMGYKVGNSLVEDDLQDVARDLIDVAKKLEIKLYLPVDFVIGQEVSENTPTKVVPWQEIPDGWMGLDIGPVSVELVKEIISDAQTIVWNGPMGVFEIDKFKHGTIEVAKLLAQSSALTIAGGGDTDHAIHKAGVYHAFDFVSTGGGAFLELLAGKELPCLVNLDDKEA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGE_SALTY
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNQDGAMGIIVNKPLENLQIEGILEKLKITPEPRDSAIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDNTVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKTPIAERWREAAKLIGIDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: PHNC_STAAR
Sequence: MSQIKFKNVSKVYPNGHVGLKNINLNIEKGEFAVIVGLSGAGKSTLLRSVNRLHDITSGEIFIQGKSITKAHGKALLEMRRNIGMIFQHFNLVKRSSVLRNVLSGRVGYHPTWKMVLGLFPKEDKIKAMDALERVNILDKYNQRSDELSGGQQQRISIARALCQESEIILADEPVASLDPLTTKQVMDDLRKINQELGITILINLHFVDLAKEYGTRIIGLRDGEVVYDGPASEATDDVFSKIYGRTIKEDEKLGVN
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TMM53_MOUSE
Sequence: MASAELDYSIEIPDQPCWSQKNRQGGKEAGKQQPVVILLGWGGCRDKNLAKYSAIYHKRGCIVIRYTAPWHMVFFSESLGIPSLRVIAQKLLELLFDYEIEREPLLFHVFSNAGVMLYRYVLELLQTHQRFRHLHVVGTIFDSGPGDSNLIGALRALATILERRPAVLRLLLLAAFALVVILFHFLLAPFTALFHTHFYDRLQDSGSCWPELYLYSRADKVVSARDVERMVEARLAHQVMVRGVDFVSSAHVSHLRDYPTYYTSLCVDFMHNCVQC
What is the function of this protein?
Negatively regulates bone morphogenetic protein (BMP) signaling in osteoblast lineage cells by blocking cytoplasm-nucleus translocation of phosphorylated SMAD1/5/9 proteins.
What are the official names of this protein?
Transmembrane protein 53, Nuclear envelope transmembrane protein 4.
What is the protein family that this protein belongs to?
Belongs to the TMEM53 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FAR_CAMFO
Sequence: MVSIRLTFALAIVAIIFAFSVDAAYKKPPFNGSIFGKRSNTMTDYEFTSRALSAICEVASETCTAWMSRQESN
What are the official names of this protein?
SIFamide-related peptide, SIFa, AYKKPPFNGSIF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GASAE_ARATH
Sequence: MALSLLSVFIFFHVFTNVVFAASNEESNALVSLPTPTLPSPSPATKPPSPALKPPTPSYKPPTLPTTPIKPPTTKPPVKPPTIPVTPVKPPVSTPPIKLPPVQPPTYKPPTPTVKPPSVQPPTYKPPTPTVKPPTTSPVKPPTTPPVQSPPVQPPTYKPPTSPVKPPTTTPPVKPPTTTPPVQPPTYNPPTTPVKPPTAPPVKPPTPPPVRTRIDCVPLCGTRCGQHSRKNVCMRACVTCCYRCKCVPPGTYGNKEKCGSCYANMKTRGGKSKCP
What is the function of this protein?
Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation.
What are the official names of this protein?
Gibberellin-regulated protein 14, GAST1 protein homolog 14.
What is the protein family that this protein belongs to?
Belongs to the GASA family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_STRPN
Sequence: MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEHYADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGDWGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAKNPELENKDQVAHAVGIGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_ACTP7
Sequence: MAKNIQAIRGMNDCSPTESPLWQWIENKVRNVLAGYGYSEVRMPIVESTPLFARAIGEVTDVVSKEMYTFWDNDEQLTLRPEGTAGCVRAAIERGWIYNNEQRLWYMGPMFRHERPQKGRYRQFHQAGVEVFGIPNPEIDAELIILTARLWKELGIDQHVSLQLNSIGSLEARANYRSALVKFLENHTALMSDEEKERLVKNPLRILDTKNQALQEVLNDAPKLLDYLDDDSREHFAHLCHLLDAMGIAYEVNPKLVRGLDYYNKTVFEWVTSALGSQGTVCGGGRYDGLVEQLGGHATQGVGFAMGLERLVLLVQEVNKEINLPKAVDVYVVYSGEGATLNAFQMAERIRSELPQLGVMTHCSGGNFKKQFKRADKVEAQIALVIGESEVEQQTVVLKDLQSGAEQVIIAQADLIAELTKRF
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_CLOBA
Sequence: MGMTMTQKILASHAGLESVKAGQLIEVNLDLVLGNDITTPVAINEFKKFGVDKVFNKSQIAIVPDHFTPNKDIKAAEQVKYVREFSNKMGIENFFEVGEMGIEHCLLPEKGLVVAGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATGQTWFKVPSAIKFILKNKPAKWVSGKDIILHIIGMIGVDGALYKSMEFVGDGLNYLSMDDRFTMANMAIEAGGKNGIFPVDDKTVEYLKEHTEKEWKIYEADEDAEYDEVIEIDLSTLKPTVSFPHLPDNTRTIDNANRVNIDQVVIGSCTNGRISDLRIARGILKGKKVKKGIRCIVIPGTQKIYLQALEEGIIKDLIEAGAVVSTPTCGPCLGGHMGILAKGERCVSTTNRNFVGRMGHVESEVYLASPAVAAASALTGKITDPELV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: MICA1_BOVIN
Sequence: MASTISTNPAHAHFESFLQAQLCQDVLSSFQGLCGALGVEPGGGLSQYHKVKAQLNYWNAKSLWAKLDKRASQPVYQQGRACTGTKCLVVGAGPCGLRAAVELAMLGARVVLVEKRTKFSRHNVLHLWPFTIHDLRALGAKKFYGRFCTGSLDHISIRQLQLLLLKVALLLGVEIHWGITFTGLQPPPKKGSGWRAQLQPSPPAQLAKYEFDVLISAAGGKFVPEGFTVREMRGKLAIGITANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCLLRLGVLHKDWPDTERLLGSANVVPEALQRFARAAADFATHGKLGKLEFARDAHGRPDVSAFDFTSMMRAESSARVQERHGTRLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMVKRWAEGAGPLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPSQVRDLYDMEAKEPVQRMSDETDSGKAATGAVGSQEELLRWCQEQTAGYPGVHVTDLSSSWADGLALCALVHRLRPALLEPSELQGMGALEATSWALKMAEHELGITPVLSAQAMVAGSDPLGLIAYLSHFHSAFKSVPHNPGSVSQGSPGTASAVLFLGKLQRTLQRTRTQENGEDAGGKKPRLEVKAETPSTEEPPVPKPDEPMTPPSQQQDASAEDLCALCGQHLYILERLCADGRFFHRSCFRCHICEATLWPGGYRQHPGDGYLYCLQHLPQTGHEEDSSDRGPESQDLPMSSENNTPSGPATPVDLHQGTSPVPNPIQPTRRLIRLSSPERQRLSSLHLTPDPEMEPPPKPPRSCSTLAHQALEASFKGWGMPVQSPQVLEAMEMGEEERSSSSEEETEEEEDVPLDSDMEHFLRNLAENSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQAIQRRLNEIEAALRELEARGTELELALRSQSSSPEKQKALWVEQLLQLVQKKNSLVAEEAELMITVQELNLEEKQWQLDQELRTYMNREETLKTAADRQAEDQVLRKLLDVVNQRDALIRLQEERRLSELASEPGVQG
What is the function of this protein?
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization.  In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2).  Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments.  Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.  Involved in regulation of lamina-specific connectivity in the nervous system such as the development of lamina-restricted hippocampal connections.  Through redox regulation of the actin cytoskeleton controls the intracellular distribution of secretory vesicles containing L1/neurofascin/NgCAM family proteins in neurons, thereby regulating their cell surface levels.  May act as Rab effector protein and play a role in vesicle trafficking.
What are the official names of this protein?
[F-actin]-monooxygenase MICAL1, Molecule interacting with CasL protein 1, MICAL-1.
What is the protein family that this protein belongs to?
Belongs to the Mical family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: TRM5_PLAF7
Sequence: MFFKALFLSLYLFFFISYAEIIFCIRIKRNNLYNFQNMTNSLNIKNLDDVKEKVKYEKHTYCLLLDKYKVNKILKNKRAKFWLLDIYKFPSVLKYKEYKNCFLQNDHNDKNNHMLNFIYNNYLKKRNHQNVKNESENGNYNNDHNDHQTCNNMNIFFSNEYLKSLSNFNEEDFRLIPLNDFFNKILLELFYKQREEIIHDDVIYSKNNIKSLSHVFNDNSPEQYRQKEKQQQVGNIIMCNSNSPEQYRQKEKQQQVDNIIMCDENLCETLIKDDEINENDDNKNPLENLCEDFKKDKDDIENIYNMHKLEYIEELFELIKEEDIKFQRVKLEFGYDNMNTSEILRKIFPCINEIIHKFEIIGHIAHLNFCDKLESCKKIIAEIILDKNKSIKTVINKKDILNNTHRTFNIELLAGENNYVTQLKENNIRVKLNYELIYWNSKLKKERDRIYNLVKDNSIIIDVFGGVGIFSLSLSKKSCLCFSNDINEHAYKYMNINISMNKNKNILTYNMDGREFLEKLFNLKIFSKNNNVLTLYINDQNQKNISLDVLNSKNHIITGNGKNKSKNKNENKNENKNENKNENKNENKNENKNENKNENKKDIQNNNMCEKENNISDRKCPYIHNNNNQRNITCDNNNNNNNMNVSGNNSIHQYTDMYEHKFKYQKIGEENMDNSKNEENHKIDINLNIYEDIHILMNLPQTALEFLNVFKKYKKEKNDELRNVFIHCYYFAKPEFFYEHAEKNILLHFNQLPKDIKITEIRKVSPSKLMYVVEFNLKDLL
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: CCME_KLEP7
Sequence: MQARRKTRLYIVLAVLAGLGLTVSLTLYALSSNIDLFYTPGEIIYGKTETRALPHTGQRLRVGGYVQPGSLQRDPQTLDVRFKLYDARGVVDVSYKGILPDLFREGQGVVAQGVLDGERHITAQQVLAKHDENYTPPEVKNAMTPEKTGAQP
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: Y674_YERPE
Sequence: MSISLIQPERDLFSYQPYWAECYGTAPFLPMSREEMDILGWDSCDIIVITGDAYVDHPSFGMAIVGRMLEAQGFRVGIIAQPDWTNKHDFMRLGEPNLFFGVTAGNMDSMINRYTADRKLRHDDAYTPDNQSGKRPDRATLVYSQRCKEAYSHVPVLLGGIEASLRRIAHYDYWSDTVRRSVIVDAKADMLVYGNGERPLVEVAHRLAAGEKITDIQDVRNTVVMRKTPLPGWSGVDSTRLDKPGRIEAIPNPYGEDLPCATDDISIPEAKPITVRAAKPKPWEKTYVLLPSYEKVKADKVLYAHTSRILHHETNPGCARALMQKHGDRYIWINPPAIPLSTEEMDSVFALPYQRVPHPSYGKSPIPAYDMIRFSINIMRGCYGGCSFCSITEHEGRIIQSRSEDSIIREIEEIRDKVPGFTGIISDLGGPTANMYMLRCQSPRAEQTCRRASCVYPEICPHMDTNHQPTISLYRRARDLKGIKKILIASGVRYDLAVEDPRYIKELASHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYQRFKELFDTYSKQAGKEQYLIPYFISAHPGTEDKDMVNLALWLKKNRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKVDYKSEEVVVPKGDRQRRLHKALLRYHDPANWPMLRSALEDMGLQHLIGARRECLVPAPTLEEQREARRALRHHTPALTKHTSITRQRQPSNRAPAASAGKKAPTVANGTSSAHSTSANQSTSANQSTSAAHSTLATKKSAGKTGVNKAAVNKPSAGSRGKNRQH
What are the official names of this protein?
Putative UPF0313 protein YPO0674/y3502/YP_2990.
What is the protein family that this protein belongs to?
Belongs to the UPF0313 family.
Protein: FOLD3_RHIWR
Sequence: MERVGMNGAEIIDGKAYAAGLRARVATAVPAFRVAAGRAPGLAVVLVGEDAASQVYVRSKHKATVEAGMESFEHRLPATASETELLALVERLNADDRVDGILVQLPLPPHIDEKKVIATIDPDKDVDGFHVVNAGRLAVGEAGYVPCTPLGCLMLLKDRRGDLSGLEAVVIGRSNIVGKPMAALLLAENCTVTIAHSRTRDLAEVVRRADIVVAAVGRPEMVRGDWIRPGATVIDVGINRVPGAEPGKTRLVGDVAFAEAAAVAGAITPVPGGVGPMTIAVLLRNTLVAAHRRAGVALPEGAIG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 3.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PEPQ_PHOLL
Sequence: MEKLASLYHEHISTLQQRTCEALARNQFDALLIHSGELQHIFLDDRDYPFKVNACFKAWVPVTKVPNCWLWVDGINKPKLWFYSPVDYWHSVEPLPTSYWTKEVEMIHLANAGDINSALSTYVKQNVAYIGCSPQRAKEIGFSERNINPKSVLDYLHFHRSYKTDYELVCMREAQKTAIVGHLAAYEAFQAGMSEFDINISYLMATGHRDTDVPYNNIIAMNENAAVLHYTALQHNAPSDIRSFLIDAGAEYNGYAADITRTYSAKSNNEFASLIKDMDAEQKALISTIKVGTRYTEYHIQMHHRIAKLLKKYGIVKDVSEEVMVEEGLTTPFFPHGIGHPLGLQVHDVAGFMQDDTGTHLAAPDMYPYLRCTRILEPRMVLTIEPGLYFIESLLAPWRESEFSKHFDWNKIGTLKLFGGIRIEDNIVIHENKVENMTRDLQLP
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: STX67_LYCMC
Sequence: MKNIVIIITVAVSFNLFGESLQMVSSEKYPLYRDDSKYDCLINGYNPYCQDICKLHNTKEGYCKNYFCICEKLSKENVKFLSEIIDTCNERLDKIL
What are the official names of this protein?
Neurotoxin 67.1.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PEX15_YEAST
Sequence: MAASEIMNNLPMHSLDSSLRDLLNDDLFIESDESTKSVNDQRSEVFQECVNLFIKRDIKDCLEKMSEVGFIDITVFKSNPMILDLFVSACDIMPSFTKLGLTLQSEILNIFTLDTPQCIETRKIILGDLSKLLVINKFFRCCIKVIQFNLTDHTEQEEKTLELESIMSDFIFVYITKMRTTIDVVGLQELIEIFIFQVKVKLHHKKPSPNMYWALCKTLPKLSPTLKGLYLSKDVSIEDAILNSIDNKIQKDKAKSKGKQRGVKQKIHHFHEPMLHNSSEEQVKVEDAFNQRTSTDSRLQSTGTAPRKKNNDITVLAGSFWAVLKHHFTRSVLNKNGLLLTGLLLLLCLKKYKSLMAIFKHVPAAFHTVYPQIVGLLKLLASI
What is the function of this protein?
Peroxisomal docking factor that anchors PEX1 and PEX6 to peroxisome membranes (PubMed:12808025, PubMed:9405362, PubMed:16007078).  PEX26 is therefore required for the formation of the PEX1-PEX6 AAA ATPase complex, a complex that mediates the extraction of the PEX5 receptor from peroxisomal membrane (PubMed:12808025, PubMed:9405362).
What are the official names of this protein?
Peroxisomal membrane protein PEX15, Peroxin-15, Peroxisome biosynthesis protein PAS21.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: Y2476_STAAN
Sequence: MTEPIISFKDFSFQYHSQATPTLQNINVDIYPGEKVLVVGASGSGKSTFANCINGLIPFKTKGNITGELYINNQDATVSCLHDRSNVVGTVLQDTDGQFIGLTAAEDMAFLLENNCVEQDDMKKNVSYWAEKVGMIEHLNHRPQDLSGGQKQRVSLGGILIHRTPILILDEPLANLDPATGHETLRLLNNIHEETKSTMIIVEHRLEESLDDTFDRVLLFKDGKIIANTTPSDLLKSSKLKEAGIREPLYCTALKYAEVDVESIDNLANLRDVCMSEHVKFKVKKWIDETSANNDNKYKSEPLLELNEVCVQYSDYSNSVLNNVQLNVYRREMLSIVGHNGAGKSTLAKAICGFLDITGNIQFCNRGFNQLSISERSEFVGYVMQNPNHMISEKMIYDEVALGLRARGMKESDIKIRVENVLKICGLYAFRNWPIAALSYGQKKRVTIASVLVLNPEIIILDEPTAGQDFYHYNEIMSFLIELNRQGKTIIMITHDMHLLSEYSSRTVVLSKGQVVADTTPVLILNDKKICEIASLRQTSLFEMAEYIGISEPQKLVQLFINHDRKVRRQ
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein SA2476.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TCDA_ECOLI
Sequence: MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG
What is the function of this protein?
Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine.  TcdA is also part of a sulfur transfer pathway; is able to accept sulfur from CsdA directly in vitro, but CsdE might act as the sulfur donor in vivo.
What are the official names of this protein?
tRNA threonylcarbamoyladenosine dehydratase, t(6)A37 dehydratase.
What is the protein family that this protein belongs to?
Belongs to the HesA/MoeB/ThiF family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DD19B_HUMAN
Sequence: MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA export from the nucleus (PubMed:10428971).  Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins (PubMed:10428971).
What are the official names of this protein?
ATP-dependent RNA helicase DDX19B, DEAD box RNA helicase DEAD5, DEAD box protein 19B.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Note=Associates with the nuclear pore complex cytoplasmic fibrils.
Protein: FABH_EHRRW
Sequence: MRSSRILGIGSYLPKSLVTNDDLACTVATSDEWIVKRTGIRQRYIAADDQMTSDMAVEAAKLALNDSGINKQDVDLIVVATTTPDRTFPSCATIVQSKLECKNAFAFDIQAVCSGFIYAMAIADNFIKSGQVNVSLVIGAEVMSRILDWKDRSTCVLFGDGAGAVVLSNNSARNTGVISTILYSDGTLHNLLYTSGGTAYNGVAGTICMNGTVVFEHAIEKLSASIVEILNKNNLSIDEVNWFVLHQANIRIIELVARRLKIPSEKMVISINQHANTSAASIPLALSYAKNSGKLKQDDLVVLAAIGAGITWGVCLVRM
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_CRYNB
Sequence: MVKLPSASRIRSLATVPSTATRAFATVNPTPPAAQPTKSKPRFEKLDDGLTFDDFLSGDVPPENERVVLGNTKQPRLPSFLKHPIPTGASYSGIKKELRGLGLHTVCEEAKCPNIGECWGGGKGNATATIMLMGDQCTRGCRFCSVKTSRAPPPLDVHEPENTAEAISRWGLGYIVLTSVDRDDLVDGGAAHIASTISKIKQKAPNILVEALTPDFATKGVNVIHTVASSGLDVFAHNVETVERCTPFVRDRRAGFSQSLKVLEEAKKGAKAAGREILTKSSIMLGVGEMEEEIHETLRRLRASDVDVVTFGQYMRPTKRHMKVDRYVEPEEFAKWKNVAEGMGFLYVASGPLVRSSYKAGEFFIENVLKKRRAAAAEHAASQLSTQPPEIAAKV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOZ_BEUC1
Sequence: MSGTVAAPEGITDPPIDELLTAADSKYALVIYAAKRARQINAYYAQLNEGLLEYVGPLVETRNQEKPLSIAMREINKGLLTVEATESTED
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.