PharMolix/UniProtQA huggingface dataset:
Protein: HEMA_I01A0
Sequence: SLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKASPANDLCYPGDFNDYEELKHLLSRINHFEKIQIIPKSSWSNHEASSGVSSACPYLGKSSFFRNVVWLIKKNSTYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPTTYISVGTSTLNQRLVPKIATRSKVNGQSGRMEFFWTILKPNDAINFESNGNFIAPEYAYKIVKKGDSAIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNTPQRERRRKKRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVKNGTYDYPQYSEEARLNREEISGVKLESMGTYQILSIYSTVASSLALAIMVAGLSLWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: DCAM1_BRAJU
Sequence: MSLSAIGFEGLRERLEVSFFEPSLFLDTHGKGLRALSKSQIDEILAPAECTIVSSLSNDELDSYVLSESSLFIFPYKIIIKTCGTTKLLLSIEPLLRLAGGVSLEVKSVRYTRGSFLCPGGQPFPQRNLSEEVSVLDGHFAKMGLSSVAYLMGDDDETKKWHVYSASAPAKNSNGDNNVYTLEMCMSGLDKDKASVFFKNESSSAGSMTDNSGIRKILPQSQICDFEFEPCGYSMNSVEGDASSTIHVTPEDGFSYASFEAVGYDFTTMDLSQLVSRVLTCFEPKQFSVAVHSSVAQKSYDHSGLSVDLEDYGCRETTVGVSRRRERNSDVSEVREAGNVLWFSEIDLKCEWSSNSSCTSEDEKEEGI
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme 1, AdoMetDC 1, SAMDC 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: RECA_ECO57
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1487_METJA
Sequence: MEENTALVVYYTKLHKNSFNALIGALEIDEYFDNLPIYFANKKDIFNLKEVLKKYDKVVIAISFFTTELWKTYELINELKAKYQSYRNKIIYLAGGPHPTGDPKGTLKLGFDVVCIGEGEETFPEFIKAVNEDEDYKKVKGIAYLNDNEFIYTGRRKPVDLNKYPPFPVKHNKFGHIEITRGCPYKCYFCQTPRIFGKKIRHRDVENIYKYVEIMAERNLKDIRFITPNAFGYGSKDGKTLNIDKIEKLLESIREILGNNGRIFFGTFPSEVRPEHVNIETVDLILRYADNKNLVIGAQSGSEKVLELCHRGHTVEDVYNAVRVARKAGLGVDVDFIFGLPGETEEDVEKTIKVMKDLIKMGAKIHAHTFMPLPQTPFAKANPGKVDKKIIRAMRYEIPKGIFHGTWHNQEIIAQKISKYLKTGKL
What are the official names of this protein?
Uncharacterized methyltransferase MJ1487.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: COA6_MOUSE
Sequence: MAAPSMKERQACWGARDLYWRCLDDNAEDAARCQKLRSSFEASCPQQWIKYFDKRRDYLKFKEKFEAGGFQSSQSTENS
What is the function of this protein?
Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2.  Thereby, may regulate early steps of complex IV assembly.  Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis.  May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.
What are the official names of this protein?
Cytochrome c oxidase assembly factor 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6B family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion intermembrane space.
Protein: TM6S2_RAT
Sequence: MDIPPLAGRTVAMSLGALPVSYVLNQVSAFSQPLCVVLTSALVLGLLFMAVYSLSHGEITYDPLYAVFVVFSFTSVVDLVIALQEDGYLMGLMDFYAKEGEPYLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSLLVFLPGNILGKYSSEIRPTFFLAILYMLVPCWAGMRIFNQSPAPSSCTCDVVQEEQKKSLLQRPADLTLIVYLILAAFFTVFRGLVVLDCPADACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALTFPGCSWLPDWALVFAGAIGQAQFSHMGASMHLRTPFTYRVPEDTWATFLLSNLLFALGPHLLALRCLWRPAFFLRAAPPSSPQDQGKKQQ
What is the function of this protein?
Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content.  May function as sterol isomerase.
What are the official names of this protein?
Transmembrane 6 superfamily member 2.
What is the protein family that this protein belongs to?
Belongs to the TM6SF family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein.
Protein: CHZ1_SCLS1
Sequence: MSAQTGSTNVSADKGKGKSVAEPQDVTMGEGEDSSSEDDVRSQGLKTAAREHYLTTYIAEEVEEEASDNEIDKSNIIQGRRTRGKKIDFAAAAKDLPAEDDEDEDDDFQSEGEDDDEMGGN
What is the function of this protein?
Forms a chaperone-bound H2A. Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A. Z histone replacement in chromatin.
What are the official names of this protein?
Histone H2A.Z-specific chaperone chz1.
What is the protein family that this protein belongs to?
Belongs to the CHZ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROA_PROM5
Sequence: MNTNDIRTVKGEKSLQGTIKVPGDKSISHRSLIIGSIAEGETNIEGFLYSEDPLSTADCLRKLGVHIPEIKKDQPFTIRGLGIDGFREPKEILNCGNSGTTMRLLMGLLAGQTDRNFILTGDKSLNERPMGRVSKPLSLMGGKIYGRENGTKAPISITGNKLKGCVIGTPVASAQVKSAILLAGLNASGTTSVIEPASSRDHTERMLKAFGADIKIRGELGRNIVIKSGNNLTGQNILIPGDISSAAFWMIAASIVPESEILVKNVGLNPTRTGILHVMDEMGCDYKIIEKSTIAGEPIGSIKVKYVSNLKPFKVQGDILPKLIDEIPILTVAACFCNGVSEIKDAKELRVKETDRLKVMARQLKKFGANITEKEDGLIITGESKFHSAEVDSETDHRVSMSLAIASLLAKGSTRIARAGASNVSYPTFWDDLEKLIN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF90_TRICV
Sequence: MDLLTKLLVFLIHIDQETILNFFGISDPNTIVINSDYQTIFENSELIPISTNVSLETLRIIVQAIIDYSKTGLSLVDIENICLLITFIRFIILAVKYNIKTSFYICSISLFAAALWYFHAKEVLLNWSGSIKGLGMKELSRARSSVIDDKNAYRLSYRSLIVTEFRKQLPGKFSFTDSEIRSSNDFFSLKFALTKAAVRDEYRIDPISMVFSRLPKSLTPVTDKIYYTIFDNLLPRIVNQCIRTFKAMWPVTSWVYITRVWKQYCPYLIRWHWTFLQTYDWIEQYLFKLAFRIAIYAWSLQREGIYDRPAVIAVGLRCMLYMEFLFVFYALIHALFSQYFYVPFLTENTELHVGPRLKIAFIVVAIPIGKSIIHVGSLTD
What are the official names of this protein?
Uncharacterized protein ycf90, ORF380.
What is the protein family that this protein belongs to?
Belongs to the ycf90 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRPF_DESDA
Sequence: MLIKVCGLTRQADVDLAASFGASMCGFIFHPVSPRCVSPVQAASLESGSMLRVGVFVEQDAEEICRIMAEARLDMAQLHGRQDAACARAVGAQRVIRVIWPARYCHRALLYNELQNHADACACYLLDAGLAGGGSGVRLDWEDLNHLPSPRPWLLAGGLSAENVGLALSRCSPDGVDFNSGVEDAPGQKNAQKLAAALAVAAKQKGNRYLS
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: YBEY_STRP3
Sequence: MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVTNERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAYGLTRQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRQ_XANCB
Sequence: MAKKSVSVIAAKTAVHAAVLAPIALLGWQFWQVWQQGSDALGADPVAEIEHRTGLWALRLLLITLAITPLRQLTGQAVLIRFRRMLGLYTFFYASVHLTAYLWLDLRGFWTQIFEEIVKRPYITVGFTAWLLLVPLAITSTQGWMRRLKRNWGRLHMLIYPIGLLAVLHFWWLVKSDIREPALYAGILALLLGWRVWKRLSARRTTARHSAPPPATPR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACT7_ORYSI
Sequence: MAEEDIQPIVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVNNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKANREKMTQIMFETFNCPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFTLPHAILRLDLAGRDLTDNLMKILTERGYSFTTTAEREIVRDIKEKLAYVALDYEQELDTARSSSSIEKSYELPDGQVITIGAERFRCPEVLFQPSFIGMEAPGIHEATYNSIMKCDVDIRKDLYGNVVLSGGSTMFPGIGDRMSKEITALAPGSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWISKAEYDESGPGIVHMKCF
What is the function of this protein?
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-7.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HIS1_SHISS
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_THISH
Sequence: MAHKKAGGSTRNGRDSESKRLGVKRFGGQTVLAGNILVRQRGTQFHPGLNVGCGKDHTLFATSDGTVVFETKGPKNRKYVSVVQA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ATPB_YERPG
Sequence: MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSSDGLSRGLKVTNLEHPIEVPVGKATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEELASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IF1_STRMU
Sequence: MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNYIRILVGDKVTVEMSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_BARHE
Sequence: MAHKKAGGSSRNGRDSESKRLGVKKFGGEAVIAGNIIVRQRGTRWHPGDNVGIGKDHTLFALSKGMVSFQRKANNRSYVSVIPVVETVE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ATP6_ANASK
Sequence: MTAATLVTLALSLSLAQHDAAPAPAPAAVEQHGAAPEAAASADPHAAPAGEHGAAVEAHAAAAGEHGEAAGHEGGHDESLGAVMLHHVTDGYVIEHPGFCNGAFAWNCEWDLRATFGDALKFGKLDLTPTKHVIMMWLASALLLVVVLAAVRKKSLVPRGLYNFIELLVAFVRNEIAVKNIGEKDADRFTPYLVTAFFFILFLNLFGLLPFSATATANLSVTVAMALFTFFITQYAAIRAMGMGGYVAHLTGGVPKSLAPLWLIMVPVEFLGLFTKPFALTVRLFANMLAGHFVILALLGLIFALGTPWVAFGSVPMALSIFLLELFVAFVQAYIFTMLSSLFIGAGLVHHGDDHGHAEEHGHAGPGMGSEHGSHVAGASPGHG
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INT1_MOUSE
Sequence: MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQASESKTTSTLLKPAPSGLPSERKRDASASLSGTSALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGSEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDKGEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSVSKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRVLVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADSTASGEEDDEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDIGETDALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPSCSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRSGDSEFSELLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMTTLLSSPHGGTLALAMHHSHFLSCPLMRQLYQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARHRISDVRSGLLHLADALSFHGDLEVANSTARAVIATLRSGEKCPVEPELISKVLRGLIEVRSPHLEELLTALFSATTETSCPSPASGPIVVVSSLLLQEKEELLGPSKQEVEGASTEAMRLGPASGLLVDWLETLDPEVVCSCPDLQWKLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHCCIRVLLGKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRSNDESIGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVPEVLLQSEGATSSSICKLDGLVHRFITLLADTSDSRSSESRVADANMACRKLAVAHPVLLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFFLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRHLAPFISKFVQFIHKYVGCSAPAAVAFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRTDQGLDEEGEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLSRGRAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGVYGQIDTSAQISEALKILHMEAVM
What is the function of this protein?
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 1, Int1.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: Y465_BACCN
Sequence: MGRKWNNIKDKKASKDANTSRIYAKFGREIYVAAKQGEPDPESNQALKVVLERAKTYSVPKSIIDRAIEKAKGGSEENYDELRYEGFGPNGSMIIVDTLTNNVNRTAADVRAAFNKNGGNMGVNGSVAYMFDATAVIGLEGKTADEVLEILMEADVDARDILEEEDSVIIYAEPDQFHAVQEALKAAGTTEFTVAELTMLAQNDVELSEEAQAQFEKLIDALEDLDDVQQVYHNVDLGE
What are the official names of this protein?
Probable transcriptional regulatory protein Bcer98_0465.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNS1_BTV2A
Sequence: MERFLRKYNISGDYANATRTFLAISPQWTCSHLKRNCLFNGMCVKQNFERAMIAATDAEEPAKAYKLVELAKEAMYDRETVWLQCFKSFSQPYEEDVEGKMKRCGAQLLEDYRKSGMMDEAVKQSALANSERVRLDDSLSAMPYIYVPIKEGQIVEPTFISRYRQIAYYFHNPDAADDWIDPNLFGIRGQHNQIQREVERQINTCPYTGYRGRVFQVMFLPIQLINFLRMDDFAKHFNRYASMAIQQYLRVGYAEEIRYVQQLFGRVPTGEFPLHQMMLMRRDFPTRDRSIVEARVRRSGDENWQSWLLPMIIIREGLDHQDRWEWFIDYMDRKHTCQLCYLKHSKQIPTCSVIDVRASELTGCSPFKMVKIEEHVGNDSVFKTKLVRDEQIGRIGDHYYTTNCYTGAEALVTTAIHIHRWIRGSGIWNDEGWQEGIFMLGRVLLRWELTKVQRSALLRLFCFVCYGYAPRADGTIPDWNNLGNFLDIILKGPELSEDEDERAYATMFEMVRCIITLCYAEKVHFAGSAAPACESGEVINLAARMSQMWMEY
What are the official names of this protein?
Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the orbivirus non-structural protein NS1 family.
Protein: HID_DROME
Sequence: MAVPFYLPEGGADDVASSSSGASGNSSPHNHPLPSSASSSVSSSGVSSASASSASSSSSASSDGASSAASQSPNTTTSSATQTPMQSPLPTDQVLYALYEWVRMYQSQQSAPQIFQYPPPSPSCNFTGGDVFFPHGHPNPNSNPHPRTPRTSVSFSSGEEYNFFRQQQPQPHPSYPAPSTPQPMPPQSAPPMHCSHSYPQQSAHMMPHHSAPFGMGGTYYAGYTPPPTPNTASAGTSSSSAAFGWHGHPHSPFTSTSTPLSAPVAPKMRLQRSQSDAARRKRLTSTGEDEREYQSDHEATWDEFGDRYDNFTAGRERLQEFNGRIPPRKKKSSNSHSSSSNNPVCHTDSQPGGTSQAESGAIHGHISQQRQVERERQKAKAEKKKPQSFTWPTVVTVFVLAMGCGFFAAR
What is the function of this protein?
Activator of apoptosis, with grim and rpr, that acts on the effector Dredd (PubMed:9740659, PubMed:22615583).  Seems to act genetically upstream of baculoviral anti-apoptotic p35 (PubMed:7622034).  Blocks Diap2 from binding and inactivating the effector caspase Drice (PubMed:18166655).  Might regulate apoptosis downstream of Clbn/NEMF (PubMed:22964637).
What are the official names of this protein?
Cell death protein hid, Protein head involution defective, Protein wrinkled.
What is the protein family that this protein belongs to?
To D.melanogaster grim and rpr.
Protein: CH60_CLOB1
Sequence: MAKSLLFGEQARRSMEAGVDKLADTVRVTLGPKGRNVVLDKKFGSPLITNDGVTIAREIELEDPYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVTAGANPIQIRTGIRKAVEKAVEEIKVISKPVNGKEDIARVAAISAASEEVGKLIADAMERVGNDGVITVEESKSMGTDLEVVEGMQFDRGYVSAYMVTDTEKMEAVLDDVYILITDKKISNIQEILPILEQIVQQGKKLLIISEDIEGEALSTLVLNKLRGTFTCVGVKAPGFGDRRKEMLQDIAILTGGEVISEELGRDLKDVTIDMLGTADSVKVTKENTTIVNGKGDKVAIKERVSQIRVQIEDTTSEFDKEKLQERLAKLAGGVAVIRVGAATETELKEEKLRIEDALAATKAAVEEGIVPGGGTAYIDIIPKIADLTSDIIDVKLGIDIIRKALEEPVRQIANNAGAEGSVIIEKVKATEAGVGYDALNDKYVDMLKTGIVDPTKVTRSALQNAASIASTFLTTEAAVADIPEKENTPPMAPGMGMDGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_GEOSM
Sequence: MEKRLIIAVVLSIGVLYAYSFIFPTPKPVPTPGGKQAAMSSATAPAPSVAALPIAGTTPVAAPAPQAGQAPAVAKDVTVDTDLYTAVFSTQGGGLKKFVLKKYKETAGPQGKDIVLVNETAANRYALLSDSREFGISPNALYSASTGEVKVTDGGKGSLELTTTTSQGITFRKVYTFSGDAYRIGLTEEVQNVGNVALTGAVHLLQTSRVVDAKKEGRYEVYSPSTLAEGKVKLDDLEDLQKTPVQYGKDIAWSAFADKYFVDGIIADKGSISQVRITRPANDAILRDVASPTVSVAPGQRSAINYAIYYGPKDLDILKLQGSRFEEVIDYGWFGPIAKPLIYSLKFLYKYTGNYGIAIIIITFILKLVFFPLTHKSYKSMKDMQKLQPKMTELKEKFKNDRDAMNRAVMELYKTHKVNPLGGCLPMLVQIPVFFGLYRALMYSIELRHAPFYLWITDLSAKDPYYVTPIIMGATMFIQQKMTPTNMDPVQAKMMLMLPIVFTFMFLNFPSGLVIYWLVNNVLTIAQQMYINKTVE
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PQQD_PSESM
Sequence: MKHEIKHDPAFRALTPKWHHGYRFQYEPAQKAHVVLYPEGMIKLNDSASLIGGLIDGERTIAAIIAELQREFPNIPELGMDVDDFMKVAKEKYWIDLV
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.