PharMolix/UniProtQA huggingface dataset:
Protein: DUF1_YEAST
Sequence: MNQLTVSYGLISPDYCTSQDAHILPITKILYPDIPGKNYFLTSGRDGSIILHKNTQLSNEPETAATTIKNDAIRMQVHSDWASDLIHVNMKNSDPSAGDTFISVSHDFSIVLISVNAQLTTWDKKIIGDHDDYIKCIVPIHYEMSNDYELEEQEGGPDNVHDGINNGIVVDEQNNFLFVTGGLDRKIKLWCLSSGPEKMATLLHTFDNAQSNDTGSIYSMSPIIPKYSFDDNQTSRPFDFVAGDCNGDLIFYSCKYRKEVIRIQNAHRTNIKVVRTLDDSTRLISTSSDGVINVWDLNCRHDQTTGALQLPKKIGSWSWDSSIWCVQGTSLDKLYFGDSQGNVMRANLSSYEDAKLTRIFKPDHHHHHHHHHEHEEQNISTTDAKVKKYGGILDIALLPNEKLLFSFCTDSNLNVLDLTNNHFSVNEGGFALTRSSLLTNRRHVITENTKGQMQRWDIVSCELLNTFDSSEGSFDDIVMKYTSKEILSHWCTVSVKVGMLFVKINPKFLKTEVYGSALKDYQVVNNIEINSDERYNLGKIVINSLFNEFISYEVQKDKLLRKKIFSLKKKDLTNSLTLDTGYNSESKKNNKDKKRKSTFKISSTLSIGNTNSSGTPPNSAPATPVMAETIVLEEQPLLQSASDKAIDDSLELVQPLPASKKPYFRTQSSGSLLSRKFKSFRSTSGRATTGLNTPEEPKGILPDTPHVINDDSAFPQAINTTQQSKDATPESMLWNHPFKLEQKLSAISSQDLPSNNTHNKLRSSENSRANSTSTLEGNEKKKPEFMPDLLEQIQESYKQQYMNTSSLKYLTKRLPVTKIIKASSCPIIRVKSATLVLVHLWKEGSCGGRVLFSTLLPPSHVDNETVSGGKENSKPPDDEEVDLQAVDDDKLGKYDLIDGELGSRLNRRQIFEQLEENLPYWFAKALFRDIKTVEEQPKLNFLIMPWSSVGGSEAAGNENKKKFISASDTTESSGNDSSDSSLGNGNEAVSPSTQQQFHNMLKFGRPKTSEQELNPTDLPRISEANVKLVAPGMIRVKKIKLYVADRFETKTPEMKAKMEPSLWLDLLCRGQVLDNDMTLNTVRTLYWKSQGDIVLEYRRKVHNSPLVHEVNGNEGK
What is the function of this protein?
Ubiquitin-binding protein involved in the resistance to phenanthroline, sanguinarine, nordihydroguaiaretic acid (NDGA), isopropyl (N-3-chloro-phenyl)-carbamate (IPCPC) and guanosine 5'-O-(2-thiodiphosphate).
What are the official names of this protein?
DUB-associated factor 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_STREM
Sequence: MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLERLGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFETFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVAKTFVAERKKLGFPLLDDASRVALLAED
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED27_ANOGA
Sequence: MNLEPINNALSQLRVLRSSVGQVFETLGTGVRADHGEEGKEQKFLQELQELLNSVNANLKDFESCINDLTPPQTPLTLANSAYLSLETNLERQALYPHLVQSYKWHDKLHEYSTFASTLLQQNSLKRSYYTNTKRRRSLPSSHLATPQMVENLIGSIHYNNMNLKIARPFMTNAILHITIARVLRAAVILKGLLIEWVTVKGYEESLLDGVDEQWTESRHQVFRKVQDHAHSAMLHFFSPTLPELAIRSFITWFRSYVTLFADPCKKCGKHLHNTLPPTWRDLRTLEPFHEECKQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 27, Mediator complex subunit 27.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 27 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNPH_SCHPO
Sequence: MTATSFLHQAKQQPHHTEPYIKALEAREYIIEQVPEELSKPKVAIICGSGLGTLASGLSAPVYEVPYEDIPHFHVSHVPGHASKLYFAFLGEKRVPTMILAGRYHSYEGYPIEATTFPVRLMKVMGVEVMVVTNAAGGLNQGFKVGDLMILKDHINFPGLAGMNPLRGPNAHEFGVRFPPLSDAYDLELRKLVYDAAKAHKVSRTIHEGCYAFVSGPCFETRAESRMLALMGADCVGMSTVPEVVVARHCGIRVLAISLVTNNVVVEESPSAKDLVEVDSNVMSKGAANHLEVLEVGIAAAADVRTMVETIVNFI
What is the function of this protein?
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.  Cleaves guanosine and inosine (By similarity).
What are the official names of this protein?
Putative purine nucleoside phosphorylase, PNP, Inosine phosphorylase, Inosine-guanosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TPS1_INUHU
Sequence: MATQKSTTALDAKSKMTTDLVRPLANFPSSIWGDRFMSLSIDKSELKTYDKVIEKQKQELRRLIIDPSMDSNKKLSLINSVYRLGLTYLFEEEIEGQLDKLFKEIDMQEACNEADLYTISVNFQVFRQHGYKLSCNVFNKFKDYTSDHKFKEYIMADVRGMLGLYESTQLRIRGETILEEAFAFTESQLKGVLDTLEGNIARQVKHALTSPFHRGLRTVEARIYFSNYEEECSTYDSLQKLANAHFNYLQLQHKEELASVIKWGEDMDFKTITPYARDRIPDLYLWGLGLFSEPHYSQARILISKMAQLICVLDDTYDAYATIDELHLLTNAINRWELSATEQLPEYMKPLYKVLLNEHVELEKQLSSKGKSNFVNASKKAFQELAMGYLQEAEWRHNGKVPSFQEYLKNGLITSTYNVFAKSSLICMSDIVTEEACTWYDSDPIILQATGLLGRVYNDISTFQFERKRAQQQITSIEAYMKTFGVPENVALEELKKMVEIAWNDINKGCLNTNEISKKLLAPIVNLARMTDVIYRYNDKFTFPEKTIEEYITLLFCESIPKN
What is the function of this protein?
Sesquiterpene synthase that catalyzes the formation of sesquiterpenes and sesquiterpenoid alcohols (PubMed:27231873).  Converts farnesyl diphosphate (FPP) to 10-epi-juneol (PubMed:27231873).  Converts FPP to tau-cadinol (PubMed:27231873).  10-epi-juneol is the major product (PubMed:27231873).
What are the official names of this protein?
10-epi-juneol synthase, Tau-cadinol synthase, Terpene synthase 1, IhsTPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: PSBY_PROM9
Sequence: MLRAIVVFAPIIAAVAWVVFNIQKPAREQWDRQFGEK
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PGK_NEUCR
Sequence: MSLSNKLSIEDVDLKGKRVLIRVDFNVPLDAEKKVTNPQRIAGAIPTIKYALDHGAKAVVLMSHLGRPDGKPNPKYSLKPVVPELEKLLGKKVTFAPDCVGPEVEEIVNKADNGEVILLENLRFHIEEEGKGTDAEGNKVKADKAKVEEFRKNLTKLGDVYINDAFGTAHRAHSSMVGIDLPVKAAGFLMKKELQYFAKVLESPQRPFLSILGGAKVSDKIQLIDNLLDKVNTLIVCGGMAFTFKKTLQNMPIGNSLFDEAGAKIVPDLVKKAEKNNVKLVLPVDFTIADKFDKDANTGYATDKDGIPDGWMGLDCGEESVKLFTQAINESQTILWNGPAGVFEFDKFAKGTKATLDACVKAAEEGRTVIIGGGDTATVAAKYGVEDKLSHVSTGGGASLELLEGKALPGVVALSERQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3270_CHESB
Sequence: MTDGRRIERTSIDPKLLELLACPVTKGPLKWDPAKNELISAKAGLAYPVRDGVPVMLPGEARPLEPDKPRR
What are the official names of this protein?
UPF0434 protein Meso_3270.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: DOP1_MOUSE
Sequence: MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPALLGLYEMYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNTLLEKVAAAVEQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMIRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAIIGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRQSFFLSRRTLHARLQVGPGDSSDSSELQLTNFCLLVDFLLDIVSLETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLSAGNGGVVQFPSGQNSTVKEWEDKKQVSSVSMENPAEVFEDGENPPSSRSSESGFTEFIQYQADRPDDLDRELNGQGAATIPIGSTSSETETASTVGSEETVIQPPSTFTQGAAGRSGKAVQKTAMQCCLEYVQQFLSRLINLYIIHSDSFPQALAADHQGDFSRIQRETSKWDRDSQGDAKERNIHTPKTSKEYLSAFLAACQLFLECSSFPVYIAEGNHTSESHSEKPDTDCEHAHPPQWLRTLMSACSQARDFRVQSAAVSLVMDLVGLTQSVAMVTGENINSMEPAQPLSPNQGRVAVVIRPPLTQGNLKYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVPSSSICEDVVSQQLTHKDKKIRMEAHAKFAVLWHLTRDLHINKSSFARSFDRSLFIMLDSLTSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEENDKHFMQNFTCNNVSQVHLIASKGNGEKPLTMDEMENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENANAHEDSHMAKASSPDDDVQQVVFDLICKVVSGLEAESESVTSELEIESLQTKSSDLDPGKEATKIEDQAPQHSQHVLLSDDSPRFLSVSTEEGCECLANGISRNSSSPCISGTAQTLNDSSVPSETKSRQRSHSSIQFSFKEKLSEKVSEKETIVKESGKQPGAKPKVKLARKKDEDKKKAASEKLKQANVFFSEGLDLENWYSCGEGEISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKTNPIAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKTAGKSMVAVEEGFSEDSLINFSEDELDNGSTLQSQLLRVLQRLIVLEHHVMTIPEENEAGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWVASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLVEARSGILSILHMIMSSVTLLWSILHQADASEKMAVAASASVTTINLGATKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKVRKLCFCRKFSFRTGADRIPVPNIVDSWTSLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVSHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAVLSSESDQYQKYLPDIQERLVESLRLPQVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRAKDEEDFKILEGLEMAKHQKNPEEDCSGRTLGWEPGHLLLTLCTMRNMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPVLYPNSFPNKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT
What is the function of this protein?
May be involved in protein traffic between late Golgi and early endosomes.
What are the official names of this protein?
Protein dopey-1.
What is the protein family that this protein belongs to?
Belongs to the dopey family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: FAB1A_ARATH
Sequence: MDSQDHKAPGFVDIVKSWIPRKSESSNMSRDFWMPDQSCPVCYECDAQFTVFNRRHHCRLCGRVFCAKCAANSIPSPSDETKDSHEEPERIRVCNYCYKQWEQGIVPPDNGASIISLHFSSSPSARSVASTTSNSSNCTIDSTAGPSPRPKMNPRASRRVSSNMDSEKSEQQNAKSRRSSDHYGHVLDSSDNQVEFFVNSSGRSDGEADDDDDYQSDFAQSYAQGNDYYGAINLDEVDHIYGSHEAHDVGVKIEPNISGFPPDQDLDSLNTETIDKTRQQENGWNDVKEGSPPCEESFEPEVVDFESDGLLWLPPEPENEEDEREAVLSDDDGDEGDRGDWGYLRPSNSFNEKDFHSKDKSSGAMKNVVEGHFRALVAQLLEVDNLPMVNEGDEEGWLDIITSLSWEAATLLKPDTSKSGGMDPGGYVKVKCIPCGRRSESMVVKGVVCKKNVAHRRMTSKIEKPRLLILGGALEYQRISNQLSSFDTLLQQEMDHLKMAVAKIDSHNPDILLVEKSVSRFAQEYLLAKDISLVLNIKRSLLERISRCTGAQIVPSIDQLTSPKLGYCDLFHVEKFVETHVSPCQVAKKMAKTLMFFDGCPKPLGCTILLKGAHEDELKKVKHVIQYGVFAAYHLALETSFLADEGASIHELPLQTPITVALPDKPSMVNRSISTIPGFTVSSAEKSPTTELRGEPHKANGDLTGNFTSSKTHFQGKLDGNDRIDPSERLLHNLDTVYCKPPETITSKDDGLVPTLESRQLSFHVEEPSVQKDQWSVLSGATEQVTDGGYTNDSAVIGNQNFNRQEQMESSKGDFHPSASDHQSILVSLSTRCVWKGSVCERAHLLRIKYYGSFDKPLGRFLRDNLFDQDQCCPSCTMPAEAHIHCYTHRQGSLTISVKKLPELLPGQREGKIWMWHRCLKCPRINGFPPATRRIVMSDAAWGLSFGKFLELSFSNHAAASRVANCGHSLHRDCLRFYGFGRMVACFRYASINIYAVTLPPAKLYFNYENQEWLQKESKEVIKKAEVLFNEVQEALSQISAKTMGAGSKGSTPNKIKLSLEELAGLLEQRKKEYKDSLQQMLNVVKDGQPTIDILLINKLRRLIIFDSYAWDECLAGAANMVRNNYLEAPKNSAPKVMGRNVSLEKLSDEKVKSIPTHVAICNDSLLQDADYETCLNQGKSFADTSGKFAIPEDVGSDRPPDCRMEFDPSEGGKDNFVESSQVVKPAHTESQFQATDLSDTLDAAWIGEQTTSENGIFRPPSRAASTNGTQIPDLRLLGSESELNFKGGPTNDEHTTQVQLPSPSFYYSLNKNYSLNSRKHIMAEDRPVYVSSYRELEWRSGARLLLPLGCNDLVLPVYDDEPTSIIAYALTSSEYKAQMSGSDKSRDRLDSGGSFSLFDSVNLLSLNSLSDLSVDMSRSLSSADEQVSQLLHSSLYLKDLHARISFTDEGPPGKVKYSVTCYYAKEFEALRMICCPSETDFIRSLGRCRKWGAQGGKSNVFFAKSLDDRFIIKQVTKTELESFIKFGPAYFKYLTESISTKSPTSLAKILGIYQVSSKHLKGGKEFKMDVLVMENLLFKRNFTRLYDLKGSTRARYNPDTSGSNTVLLDQNLVEAMPTSPIFVGSKAKRLLERAVWNDTSFLASIHVMDYSLLVGVDEERNELVLGIIDFMRQYTWDKHLETWVKTSGLLGGPKNSTPTVISPQQYKKRFRKAMTAYFLMVPDQWSPAAVVPSNSSSAEVKEEEEKDNPQAVGNKS
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate (By similarity).  Plays an important role in maintenance of endomembrane homeostasis including endocytosis, vacuole formation, and vacuolar acidification processes.  Required for development of viable pollen.  Might mediate recycling of auxin transporters.
What are the official names of this protein?
1-phosphatidylinositol-3-phosphate 5-kinase FAB1A, Phosphatidylinositol 3-phosphate 5-kinase, FYVE finger-containing phosphoinositide kinase, PIKfyve, Phosphatidylinositol 3-phosphate 5-kinase type III, PIPkin-III, Type III PIP kinase, Protein FORMS APLOID AND BINUCLEATE CELLS 1A.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein.
Protein: QUEA_CYTH3
Sequence: MKLSEFKFALPAELVAQHPAANRDEAKMMVINRATGTIEHKIFKDIINYFDEGDIMVMNNTKVFPARLYGNKEKTGAKIEVFLLRELNAELHLWDVLVDPARKIRVGNKLYFGESDLVAEVVDNTTSRGRTIRFLFDGNSEDFSKIIETIGETPLPRYIKRPIEEADKDRYQTIFAENKGAVAAPTAGLHFTKQVMKRMEIKGVNFAPLTLHVGLGSFRTVDVEDLTKHKMDSENFIIESTTADVVNKALDNKKRVCAIGTTSMRALESSVSANNRLKQNAGWTDRFIFPPYDFKIANCMLTNFHMPESTLYMMACAFGGYELMTKAYKTAIKEKYNFLSYGDVMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS3B_CVCBG
Sequence: MIGGLFLNTLSFVIVSNHVVNNTANVHHIQQEHVIVQQTQIVSARTQNYYPEFSIAVLFVSFLALYRSTNFKTCVGILMFKIVSMTLIGPMLTAYGYYIDGIVTTTVLALRFIYLSYFWYVNNRFEFVLYNTTTLMFVHGRAAPFMRSSHSSIYVTLYGGINYMFVNDLTLHFVDPMLVSIAIRGLAHADLTVVRAVELLNGDFIYVFSQEPVVGVYNAAFSQAVLNEIDLKEEVEDHVYDVPSGINCHR
What is the function of this protein?
May be a virulence factor.
What are the official names of this protein?
Non-structural protein 3b, ns3b, Accessory protein 3b, Protein X2.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses NS3b protein family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: ID4_XENLA
Sequence: MKAVSPVRPQSRKAQVPSVCGELALHCLSEHSLGVARYKMEEEETLCLQYDMNDCYSRLKRLVPTIPPNKKVSKVEILQHVIDYILDLQLALDTHPVLLRQQPPTRTPLTDLNTDPAALVVNKQGDSILCR
What is the function of this protein?
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity.  Inhibits the activity of both neurogenic (neurog1/neurogenin, neurod1/neuroD) and myogenic (myod1/myoD) bHLH factors.
What are the official names of this protein?
DNA-binding protein inhibitor ID-4, Inhibitor of DNA binding 4, Inhibitor of differentiation 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCH1_SHESW
Sequence: MALSEAAVKVQAALLERGLETPMLPSVYSSEERKDKIEHHMKEILTLMSLDLSDDSLADTPRRIAKMYVDEIFSGLDYENFPKITVIDNKMGFDEMVRVQDISLTSTCEHHLVTIDGTATIAYLPRKKIIGLSKINRIVRFFAQRPQVQERLTQQVLVALQTLLETKDVAVKMDAVHYCVKSRGVMDSTSSTTTTALGGIFKSNPATRAEFLHQ
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: PP2A3_ORYSJ
Sequence: MPSSHGDLDRQIAQLRECKHLAEGEVRALCEQAKAILMEEWNVQPVRCPVTVCGDIHGQFYDLIELFRIGGEAPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALIENQVFCLHGGLSPSLDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDIAQQFNHTNGLSLISRAHQLVMEGFNWCQDKNVVTVFSAPNYCYRCGNMAAILEIGENMDQNFLQFDPAPRQIEPDTTRKTPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP2A-3 catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSGP_EBORS
Sequence: MGSGYQLLQLPRERFRKTSFLVWVIILFQRAISMPLGIVTNSTLKATEIDQLVCRDKLSSTSQLKSVGLNLEGNGIATDVPSATKRWGFRSGVPPKVVSYEAGEWAENCYNLEIKKSDGSECLPLPPDGVRGFPRCRYVHKVQGTGPCPGDLAFHKNGAFFLYDRLASTVIYRGTTFTEGVVAFLILSEPKKHFWKATPAHEPVNTTDDSTSYYMTLTLSYEMSNFGGKESNTLFKVDNHTYVQLDRPHTPQFLVQLNETLRRNNRLSNSTGRLTWTLDPKIEPDVGEWAFWETKKTFPNNFMEKTCISKFYQPTPTTPQIRARRELSKEKLATTHPPTTPSWFQRIPLQWFQCSLQDGQRKCRPKV
What is the function of this protein?
Viroporin that permeabilizes mammalian cell plasma membranes.  It acts by altering permeation of ionic compounds and small molecules.  This activity may lead to viral enterotoxic activity.
What are the official names of this protein?
Pre-small/secreted glycoprotein, pre-sGP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[Small/secreted glycoprotein]: Secreted. SUBCELLULAR LOCATION: [Delta-peptide]: Secreted.
Protein: PNCB_BACSU
Sequence: MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRRLPFENGYAVFAGLEKAIEYLENFKFTDSDLSYLQDELGYHEDFIEYLRGLSFTGSLYSMKEGELVFNNEPIMRVEAPLVEAQLIETALLNIVNYQTLIATKAARIKGVIGDEVALEFGTRRAHEMDAAMWGARAALIGGFSATSNVRAGKRFNIPVSGTHAHALVQAYRDEYTAFKKYAETHKDCVFLVDTYDTLRSGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKARKMLDEAGFTDAKVIASSDLDEHTIMNLKAQGARIDVWGVGTKLITAYDQPALGAVYKLVAIEEDGKMVDTIKISSNPEKVTTPGRKKVYRIINQSNHHSEGDYIALYDEQVNDQKRLRMFHPVHTFISKFVTNFYAKDLHELIFEKGILCYQNPEISDIQQYVQDNLSLLWEEYKRISKPEEYPVDLSEDCWSNKMQRIHEVKSRIEEELEEE
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: IF2_XYLFT
Sequence: MSQQTTIRKLAELVNTPVEKLLEQLAGAGMKFSGPDQVVTSTEKMKLLGFLRRTHGKSDVSVGTVREAPKKITLNRRRLQEVTVNAGRNKTTVNVEVRQKRTYVKPPESEYHTPTKPPIELADAERVEILRKLEESRQRNLAEQQRLAEVDRQRVEEQERKRREEEQAELERQKTESRVVEEILVKTDSNSVKPVSKPISEERTRALPRTVRPTPAARPSVSRSDDRNSNGGVRHKARGSHVIVSDEDDSARRFAGQMHLTAAERARRGSNTRGKGGGSHRSATHRGNENSIRSSGAHGFERPTVAVVREVAVGDTITVADLAQKLALKSGDMVKALFKMGVMVTITQTIDHDTAVLVSEELGHKVTRASSSDFEDALLAHTEELHGEPVPRPPVVTIMGHVDHGKTSLLDYIRRTKIAVGEAGGITQHIGAYHVETPRGVISFLDTPGHAAFTSMRARGAKITDIVVLVVAADDGVMPQTKEAVQHARAAGVPLIVAVSKIDKSTADPQRVKNELLTESVVAEEFGGDTQFVELSAKTGVGVDALLDAISIQAEVLELKAVIEGRATGTVIESSLDKGRGPVATVLVQQGRLKKGDYLVCGTHYGRVRALFDEVGHQPLAASPSIPVQVLGLSGVPDAGDDFVVVDDERLAKDVAQQREAKRRESRLVTSAGNRMEDILAQMGKGENQQVLNLLIKADVQGSLEALKQALVALSNDDIRINVIHVGVGGITESDANSAVTSKATVIGFNVRADASARKIIEVNGVDLRYFSIIYDVIDQVKQVASGLLGVEIREEIIGVAEVRDVFRSSKFGAVAGCMIIEGVVKRSKPIRVLRDNTVVFEGELESLRRFKENVDEVRNSIECGIGVKAYNDVRVGDSIECFERIEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMBD1_ASPTN
Sequence: MALLQTSLIWVVYAIAIAVLIAVASVFIYVYQTPRDRSPSVTLTCIFAITTLLATVLLLPVDVALVSSTNSSALGRRKDWATDHEVNKILFSLKVVYYLLYSLDALLCLLVIPFTYFWYEEYDEVAAEEGEQTTGNRFWAAFKYTITFIAIVIVLFLVGFFVPVAKDNHSGGLDYFKKLLTENRGERALTFALGLLITIGLCLYVLYTSTGLALLPVSLIKTAPSISAPNLKATTAMQLDSNRERQRQLEGRCGGNTELLSSKDRRELDMLVREERTLIRRQRLADEAQGEGRSWLMRAWLKTEAVFRPFKLLGGIILLIIALVIWVSMLLTAIDKATNSFCKYHCGYILGHITVFNPINWVFVQAAKVFPVDYVIFTLLVLLFFCSSVVGIAIVGIRFLWIRIFQIRKGHTSPQALLLTTAMLMLTILALNYSVSMVVAPQYATFGPQTFCDRTTGTFGEQADCSNARHLIKPCSEMIKNPAASGVCTPSIASTFLNRVTINFPFFGVIFFWGQFVFLGVYLIVVVASLFRSPKLDERQMDEDAEEAEEEGLLASTGRRLDTAWQDITGRSNRQRDS
What is the function of this protein?
Probable lysosomal cobalamin transporter.  Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity).
What are the official names of this protein?
Probable lysosomal cobalamin transporter.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: TYSY_HALVO
Sequence: MTTTPNQGTSHAPIFDLVTDVFGTGRHKPNRTGVDTISGFSKHYTVDLQEGFPLLTTKDLSGFRWNSLIHELLWYFSGEEHIRTLREETGIWDAWADEEGHLDTAYGRFWRRYPVPEEGLAGEAWPDDGHRWMNDEGTFDQLAYVLDTLDENPNSRRLVINAWHPANAAVSTLPPCHYTFVFNVQGDELNLHLTQRSGDIALGVPFNLAAYAILAQVVAQRAGFELGSFAHTIVDAHVYCGAGERGAWYGDHLDELQSRLADVQSPDEYLDVREWLLDAAPEEADGEEDYDHVPGLLLQASREPRERPALDVADVPLEDLSFEDIVLRDYDPADGIRFAVAE
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT2BA_BACTI
Sequence: MHLNNLNNFNNLENNGEYHCSGPIIKKPFRHIALTVPSSDITNFNEIFYVEPQYIAQAIRLTNTFQGAIDPLTLNFNFEKALQIANGLPNAGVTGTINQSVIHQTIEVSVMISQIKEIIRSVLGLVINSANFWNSVVSAITNTFTNLEPQVDENWIVWRNLSATQTSYFYKILFSIQNEDTGRFMAILPIAFEITVDVQKQQLLFITIKDSARYEVKMKALTVVQALDSYNAPIIDVFNVRNYSLHRPNHNILQNLNVNPIKS
What is the function of this protein?
Kills the larvae of dipteran insects by making pores in the epithelial cell membrane of the insect midgut.
What are the official names of this protein?
Type-2Ba cytolytic delta-endotoxin, 29 kDa cytolytic toxin.
What is the protein family that this protein belongs to?
Belongs to the cyt1/cyt2 endotoxin family.
Protein: RS14_DEIRA
Sequence: MANKSKLAKQKQREKTVEKYAAKRAELKAAGDYYGLTQLPRDASPTRLHNRCEFTGRPRGYVRFFGVSRIVLREMAHRGELPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: LGUL_YEAST
Sequence: MSTDSTRYPIQIEKASNDPTLLLNHTCLRVKDPARTVKFYTEHFGMKLLSRKDFEEAKFSLYFLSFPKDDIPKNKNGEPDVFSAHGVLELTHNWGTEKNPDYKINNGNEEPHRGFGHICFSVSDINKTCEELESQGVKFKKRLSEGRQKDIAFALGPDGYWIELITYSREGQEYPKGSVGNKFNHTMIRIKNPTRSLEFYQNVLGMKLLRTSEHESAKFTLYFLGYGVPKTDSVFSCESVLELTHNWGTENDPNFHYHNGNSEPQGYGHICISCDDAGALCKEIEVKYGDKIQWSPKFNQGRMKNIAFLKDPDGYSIEVVPHGLIA
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:11050082, PubMed:8824231).  Can use gamma-glutamylcysteine as a substrate (PubMed:8824231).
What are the official names of this protein?
Glyoxalase I, Glx I, Aldoketomutase, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase, actoylglutathione lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.