PharMolix/UniProtQA huggingface dataset:
Protein: COX2_TAMPL
Sequence: MAYPFELGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINDPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTSDLSPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATLTSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKHFENWSSSML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: URE3_EDWI9
Sequence: MQLTPREVEKLMVYTLADVALKRKQRGVKLNYPEAVSIITVTAMEGARDGKTVEEVMNEARSVLTRDDVMDGVVELIPNVQVEAIFTDGSRLVTVHDPIQ
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIB_BRUAB
Sequence: MRLLSLLTFSLFAVIGLAPAAQAKDKLTIYTYDSFVSEWGPGPKVKENFEKECDCEVNFVASADGVALLNRLKLEGSKTAADIVLGLDTNLTTEARASGFFAPSGIDQTNVKVPGNFKDDIFVPYDYGYFAVVYDSEKLPNPPKSLKELVEGDPAQKIVLQDPRTATPGLGMLLWMKSVYGDEAGAAWQKLQKRVLTVTPGWSEAYGLFTKGEAPMVLSYTTSPAYHMVVEKTDRYKALAYPEGNYLQIELAAQTTTGAKNPLAKKFLAFMTGPGFQDLIPETNWMFPAGKTSKPLPAAFDALPKPEKTLLIPPYEVAKNRRLWVNEWLAATSR
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.
What are the official names of this protein?
Thiamine-binding periplasmic protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL3_CLAMS
Sequence: MSTANRTFTGLLGTKLGMTQVWDENNKLIPVTVVQITPNVVTQVRTPEVDGYGAIQIAYGQIDPRKADKPSTGHFDKAGVTPRRHLTEVRTADFAEYTLGQEITVGAFEPGTKVDVVGTSKGKGFAGVMKRHNFKGVSASHGSHRNHRKPGSIGASSTPSRVFKGMRMAGRMGGERVTVLNLVVHSVDAEKGLLLVKGAVPGARGRIVFVRNAVKGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MNMG_SALPB
Sequence: MFYQDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDSVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVSRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIHGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEMGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAESADEVNAHLTTPLSREASGEDLLRRPEMTYAQLTSLAAFAPALEDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_BORBR
Sequence: MDFPREFDVIVVGGGHAGTEAALAAARAGAQTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAIATDEAGIQFRILNSSKGPAVRATRAQADRVLYRNAIRARLENQPNLWLFQQAVDDLMVQGDQVVGAVTQIGLRFRARTVVLTAGTFLNGLIHVGLQNYSGGRAGDPPANSLGQRLKELQLPQGRLKTGTPPRIDGRSINYSVLEEQPGDLDPVPVFSFLGKASMHPRQLPCWITHTNARTHEIIRGGLDRSPMYSGVIEGVGPRYCPSIEDKIHRFADKASHQVFLEPEGLNTHEIYPNGVSTSLPFDVQYELIHSLPGLENAHILRPGYAIEYDYFDPRALKSTLETKAISGLFFAGQINGTTGYEEAAAQGLLAGANAALQAQGKEPWVPRRDEAYLGVLVDDLVTRGVTEPYRMFTSRAEYRLSLREDNADLRLTEIGRRLGLVDDVRWDAFSRKRDAVAQEVERLKSTWVNPRVLPAHAAEALLGKAIEREYSLSDLLKRPNVSYEALMQARTDEGELLAGPGVLEDDVLAEQVETQVKYAGYIARQQDEVQKHLSHEQQPIPADIDYDAVTSLSFEVRQKLKTHRPETIGQAARVSGVTPAAISLLLIHLKRLHYGSRKQAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIBA_LAMGL
Sequence: TDPDADKGEFLAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_BPPF3
Sequence: MQSVITDVTGQLTAVQADITTIGGAIIVLAAVVLGIRWIKAQFF
What is the function of this protein?
Self assembles to form a helical capsid wrapping up the viral genomic DNA.  The capsid displays a filamentous structure with a length of 760-1950 nm and a width of 6-8 nm.  The virion assembly and budding take place at the host inner membrane (By similarity).
What are the official names of this protein?
Capsid protein G8P, Coat protein B, Gene 8 protein, G8P, Major coat protein, Pf3 coat protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus capsid protein family.
What are the subcellular locations of this protein?
Virion. Host cell inner membrane; Single-pass membrane protein. Note=Insertion into the host inner membrane requires YidC but not the Sec translocon. Virion assembly occurs after insertion.
Protein: EFG_PHYAS
Sequence: MARQFTLEKTRNIGIIAHIDAGKTTTTERILFHTGKIHKIGETHDGASQMDWMEQEQERGITITSAATTAFWKDHRVNIIDTPGHVDFTVEVSRSLRVLDGAVTVIDAQAGVEPQTETVWRQATEYKAPRIIFVNKMDKIGANFEYAVETLNQRLGVHANPIQWPIGAENDFTGIIDLVTLTAFEYDGSPEEKGKPIPIPSSLQDVAELKRNELIESLSNLDEELMLLYLEEKPISAEVLKKAIRKATLQASFFPVLCGSSFKNKGVVKMLDAIVDYLPAPCDVAPIVGIDEKNKEITRLNSDEEPFTALAFKVMTDPYVGKLTFFRIYAGKVNSGSYVFNTTKGTKERFGRLLQMHANSREEVKEAYAGDILAVVGLKGTTTGDTLAAEGQTIVLESMNFPEPVIEIAVEPKTKADQDKMGIALSKLAEEDPTFRVFSNHETGQTIIAGMGELHLDIIMERLKREFKIQANTTAPQVAYRETITQETETEGKFIRQSGGRGQYGHVWMRFEPNPGKGFEFVNKIVGGVVPREYVPAVQKGIQEALAGGILAGYPIVDIKATLFDGSYHDVDSSEMAFKIAASMSLKETKTKGNPVILEPIMNVEVVTPNDYVGNVIGDLTSRRGRLENQETRANAIAIKALVPLSEMFGYATVLRSNTQGRATFIMQFAKYEKTPKSITEEIIKQRS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADHX_DICDI
Sequence: MSTEGKVITCKAAVAWEAKKPLVIEDIEVQPPQKGEVRIKILYTGVCHTDSYTLSGSDPEGIFPCILGHEGGGIVESIGEGVTSVKVGDHVIPLYIPECGTCKFCTSNKTNLCSKIRITQGKGQMPDGTTRFKCKGKEIFHFMGTSTFSQYTVLPEISCCVVREDAPLDKVCLLGCGITTGFGAAKITAKVEEGSTVAIFGLGAVGLSVAQGAVDCGAKRIIGIDNNETKFGPGKDFGCTEFINPSKDLPEGKTIQQHLVDITDGGVDYSFECIGNVNVMRAALECCHKGWGVSTIVGVAPAGAEISTRPFQLVTGRVWKGSAFGGVKSRSQLPSIIDKYMDKKLKVDEYVTFTYPLNEINTAFDVMHEGKSLRSVVNL
What is the function of this protein?
Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
What are the official names of this protein?
Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, S-(hydroxymethyl)glutathione dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_YERPG
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLASTHGYQLTTIPEEADLLLLNTCSIREKAQEKVFSLLGQWKLLKEKNPQLIIGVGGCVASQEGEQLRQRAPCVDVIFGPQTLHRLPEMINHVQGTNSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTFCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAYRGATYDGDICSFAELLRLVAAIDGIDRVRFTTSHPIEFTDDIIDVYRDTPELVSFLHLPVQSGSDRILTMMKRAHTALEYKAIIRKLRQARPDIQISSDFIVGFPGETQQDFEQTMKLVADIHFDTSYSFIYSPRPGTPAADLPDNVSEEEKKQRLHILQQRISQQAMEISRKMVGTVQRVLVEGTSRKNVMELAGRTENNRVVNFEGSPDMIGKFVDVEIVNVYASSLRGILLRTEDQMDLRTHESPQSVIARTRKENEIGVGIYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_MYCLB
Sequence: MTVVSGASKASGADLLDYDVVVARFDPVFGLEVHVELSTVTKMFCGCATTFGAEPNTQVCPVCLGLPGSLPVLNRAAVQSAIRIGLALNCEIVPWCRFARKNYFYPDVPKNYQISQYDEPIAINGYLEVPLEDDTTWRVEIERAHMEEDTGKLTHLGSETGRIYGATTSLIDYNRAGVPLIEIVTKPIEGAGVRAPQIARAYVKALQDLLRTLDVSDVRMDQGSMRCDANVSLKPIGTVEFGTRSEIKNVNSLKSVEMAVRYEMQRQGAILVSGGRIAQETRHFHEDGYTSPGRAKETAQDYRYFPDPDLEPVAPSRELVEQLRQTIPELPWLSRKRIQQEWGISDEVMRDLVNAGAVELVAATVKNGASSEQARAWWGNFLVQKANEANITLDELAITPAQVAVVVALVDEGKLSIRLARQVVEGVLAGEGEPEQVMVDRDLALVRDDSVMQAAVDEALAADPDVAEKIRGGKVAAAGAIVGAVMKTTRGQADAARVRELVLAICGQG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LIPB_RHOPB
Sequence: MINDRETLDLVPLSLPPGAPAVAWQVSDALVPYPEAIAAMEARAAAIAAGQAPELVWLLEHPPLYTSGTSGKDGDLLIPRFPLYASGRGGQVTYHGPGQRVAYVMLDLKRRRPDVRAYVAALEQWIIGTLAHFNVRGERREDRVGVWVARPDKGAGFEDKIAAIGVRLRRWVSFHGIAINVEPDLTHFSAIVPCGVTDPRFGVTSLVDLGLPVTLQDVDVALRQAFEQVFGPTADAGLPADDAALLR
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_COXB1
Sequence: MNDVIIRQLAHLIPYQPLWEAMQTFTALRQSQTTDEIWFLEHEPVFTQGLAGKPEHVLNSGNIPLIRTDRGGQVTYHGPGQLMMYLLLDLNRLGLSTRTFVRTIENTVAESLQEWGIPAQGKETAPGVYVDDKKICSIGLRVRKGFSYHGLALNVAMDLTPFSCINPCGFKGLMMTQIQDYVNPIEMDAVKRTIIPLFLKNFGYNQPAIMVETSLEFLIDDHLRSFSEKLGERETVTNSRQN
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_LACPL
Sequence: MAKVESFTLDHTKVLAPYVRKITVENGPKGDAITNFDLRLVQPNKTAIDTAGLHTIEHMLAGLLRDRMDGVIDCSPFGCRTGFHLITWGEHDTVEVAKALKSSLEFIAGPAKWEDVQGTTIDSCGNYKDHSLFSAKEWAKLILSQGISSDPFVRKVVE
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RS7_LEGPL
Sequence: MPRRREVPKREILPDPKHHSELLAKFINVLMVSGKKSIAEKITYGALSVMEERVKKIKKNEEDGSETGSSGSAGAVLRYFEEALDNVRPSVEVRSRRVGGATYQVPVEVRHDRSIALGMRWIVQAARTRGEKGMMLRLAGELMDAYENKGSAVKKREDTHKMAKANQAFAHFRWN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RIR1_ASFWA
Sequence: METFCIETLASDTYGKALNVDLDRLSQAQIKYTLQELISYCSALTILHYDYSTLAARLSVYQLHQSTASSFSKAVRLQAAQSCSRLSPQFVDVVYKYKAIFDSYIDYNRDYKLSLLGIETMKNSYLLKNKDGVIMERPQDAYMRVAIMIYGMGKVVNIKMILLTYDLLSQHIITHASPTMFNAGTKKPQLSSCFLLNVNDNLENLYDMVKTAGIISGGGGGIGLCLSGIRAKNSFISGSGLRSNGIQNYIMLQNASQCYANQGGLRPGAYAVYLELWHQDIFTFLEMPRLKGQMAEQRLNAPNLKYGLWVPDLFMEILEDQIHNRGDGRWYLFSPDQAPNLHKVFDLERSQHENAHREFKKLYYQYVAEKRYTGVTTAKEIIKAWFKTVIQVGNPYIGFKDAINRKSNLSHVGTITNSNLCIEVTIPCWEGDKAEQGVCNLAAVNLAAFIRENGYDYRGLIEASGNVTENLDNIIDNGYYPTEATRRSNMRHRPIGIGVFGLADVFASLKIKFGSPEAIAMDEAIHAALYYGAMRRSIELAKEKGSHPSFPGSAASKGLLQPDLWVRCGDLIPSWEERVAQTTQGVLTRKSWRQLRLAAIQGVRNGYLTALMPTATSSNSTGKNECFEPFTSNLYTRRTLSGEFIVLNKYLIDDLKEINLWTEAIQLQLLNAGGSIQHILDIPAEIRDRYKTSREMNQKILTKHAAARNPFVSQSMSLNYYFYEPELSQVLTVLVLGWKKGLTTGSYYCHFSPGAGTQKKIIRNSEKACNADCEACLL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: CLD22_MOUSE
Sequence: MGLVFRTATQAAALLLSLLGWVLSCLTNYLPHWKNLNLELNEMENWTMGLWKSCVIQEEVGRQCKDFDSFLALPAELQVSRVLMSLCNGLGLLGLLASGCGLDCLRLGETQEGLKKRLLTLGGTLLWTSGVMVLVPVSWVAHKTVREFWDETMPEIVPRWEFGEALFLGWFAGFCLVLGGCVLHCAACWSPAPAASSHYAVAGPRDHQQHLELKQANPEI
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-22.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: OS25_PLAGA
Sequence: MNMSYLFFFFFIQLVLKYINSKVTENTICKDGFLIQMSNHFECNCNPGFVLTSESTCENKVECNANSLDKRCGDFSKCAYKDLQQKELTCKCIDGYDLEESICVPNECKNFRCESGKCVLDPKQEAKIPMCSCFIGIVPSKENNNTCTIEGQTECTLKCTKENETCKKTSGIYKCDCKDGYTFDKEENACISFSLFNILNLSIIFIISLIYFYII
What are the official names of this protein?
25 kDa ookinete surface antigen, Pgs25.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: TPMT_SHEAM
Sequence: MEPGFWHDKWQSQQIGFHQSDINPFLVKHWESLKLEGKGKVFVPLCGKSLDMEFLAAQGHEVIGSELSALAVSQFFEAAGAKPQSRTQGEHVHHSAQGVTLIEGDFFTLDEELVAGCSGFYDRAALIAWPAEMRIDYVRKLAALIPAGTPGLLITLDYPQEALIGPPFAVSPNWVEEFVGEYFEVVVLESQDVLADNPRFVKKAVPWLNEAAYLLVRK
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_AKKM8
Sequence: MSSSFGQVFRISTWGESHGTGVGVVIDGCPSLVPVTEEDIQRELDRRRPGQSDIVTPRREEDRAEILSGVLDGKTLGTPIAISVRNKDHRSSAYDEMARTYRPSHADYTYDAKYGIRAWAGGGRASARETIGRVAAGAVARAVLKQAFPDMEVVAWVDQVHHVKASVDWGAVTASAIESNIVRTADPSAAEAMIAAIKEARDSGNSLGGVVKCVVRGCPPGLGDPVFDKLDATLAHAMMSIPATKAFAVGSGFEAADMTGLEHNDPFYMQGCRVRTTTNHSGGIQGGISNGEDILMRIGFKPTATLMIDQQTVNRDGEDARLKGRGRHDACVLPRAVPIVEAMAWLCLCDHYLRQRCQRAL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL31_THEM4
Sequence: MKKGIHPEMKLVTVKCACGAEHKFYTVKENVRIDVCSSCHPFYKGAGAAGMIVDTEGRIEKFKKKYNLE
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: 1433E_MOUSE
Sequence: MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQDVEDENQ
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm.
What are the official names of this protein?
14-3-3 protein epsilon, 14-3-3E.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Melanosome.
Protein: VG67_EHV1K
Sequence: MNSDMMTAATAGTEVFRCALARRRNANPPHLVLAPTFAAAAAGGAANSSGEEAPRGERKHLFNPFGCMLGRSYFRRCREEMNEGYFAKVPTGYFPVAPSEVPCRVPVEGVVAGEVLSYSALPLPKIEKRFYKQLNDGTFVRLPFLYPEVYYEGEEEPADERYYIRADAADASSADPSTLPEEAFAKVPPAIAEGITNWQGPKRIPIPSERYVMKLGFEYQLHVTEDAFQEVNTSFMRLDLQSSPDPHPRGARQPRSRAHVSAENPEDTPVAV
What are the official names of this protein?
Uncharacterized gene 67 protein, IR6 protein.
Protein: IOLA1_GEOTN
Sequence: MTTGVQTLKNYIGGQWVESRSAKTEAVPNPATGEVLAYVPISTREDLDRAVAAAKEAFKTWSKTPVPRRARILFKYQQLLVEHWEELARLVTLENGKSYNEAYGEIQRGIECVEFAAGAPTLMMGRQLPSIATGIESGMYRYPIGVVGGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPMLANRLAELFKEAGLPDGVLNIVHGAHDVVNGLLEHPDVKAISFVGSQPVGEYVYKTAAAHGKRVQALTGAKNHSIVMPDADLKVAVREIINAAFGSAGERCMAASVVVAVGDIADELVERLVAAANEIKIGNGLEESVFLGPVIREAHKQRTVNYIELGEKEGAILVRDGRKDAAVQGEGYFIGPTIFDRVTTDMTIWKDEIFAPVLSIVRVSTLDEAIEVANKSPFANGACIYTRDGGNVRKFRDEIDAGMLGVNLGVPAPMAFFPFSGWKNSFYGDLHANGMDGVEFYTRKKMLTARW
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase 1, MSA dehydrogenase 1, Methylmalonate-semialdehyde dehydrogenase 1, MMSA dehydrogenase 1, MSDH 1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: LPXB_ECOL6
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNGARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAAVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.