PharMolix/UniProtQA huggingface dataset:
Protein: RL18_METTH
Sequence: MAHGPRYKLAFRRRREGKTDYRARYKMVETGKSRLVVRITTYHVIAQIINVGMNGDETLVSAHSKQLQKMGWLGGTSNTAAAYLTGYLCGKRALKEGIEEAVLDIGLRPAIRGSKVFAALKGAVDAGLNVPHGESVLPDESRIRGEHIMEYAESLDEEELRKRFSKYLERGLSPVDLPEHFDEIKKRIDEEV
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HSPQ_ECO81
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_KLEP7
Sequence: MSNSAMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAANDLGACAVHLVYGHGGDLLRQTLHEDNLNWVLQAEQLGTGHAMQQAAPFFNDDEDILMLYGDVPLISVETLQRLRAAKPQGGIGLLTVKLDDPTGYGRITRENGQVTGIVEHKDASEAQRQIQEINTGILIAGGADLKRWLAKLTNNNAQGEYYITDIIAMAHQEGHQIVAVHPQRLSEVEGVNNRLQLARLERVYQAEQAEKLLLAGVMLRDPARFDLRGTLQHGRDVEIDTNVILEGNVVLGDRVKIGAGCVIKNSTIGDDCEISPYSVVEDAQLQAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKHKTIIGDDVFVGSDTQLVAPVTVGNGVTIAAGTTVTRNIADNELVLSRVPQVHKQGWQRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPP2C_MOUSE
Sequence: MACLGSLHPLGSLLLLFLLLLLSPEARGEYGLVRVVSKNWSKDYCVLYSSDYVNLPRDLHHAPLLSLHDGTKTPWCPDEDSFHQAQDSSPRQRPLHQTTTMVTRGNCSFYAKGWLAQDQGAQGLLIVSRARNQQCSDTISKPQDPSKPWPALTIPVAVLRYTDMLDIVSHTYGDTDVRVAMFAPLEPVTDYNMAIIFILAVGTVAAGGYWAGLMEANKLQRRQAQRGGGLGGHNQQQTVAAERSQRAWEDDDFEDAPMDFTPAMTGAVVTMSCSIMILLYFFYDCFVYVMIGIFSLGASTGLYSCLAPILCHLPLWRYQWVLPGQRVSVTWPLLLLAGLCAMVTVLWVIHRNEDHWAWLLQDTLGVAYCLFVLRRVRLPTFKNCTLFLLALLAFDVFFVFITPLFTKTGESIMVEVASGPADSSSHERLPMVLKVPRLSFSALTLCNQPFSILGFGDIVVPGFLVAYCHRFDMQVQSRQVYYMACTVAYAVGLLVTFVAMILMQMGQPALLYLVSSTLLTSLAVATCRQEFTLFWTGQGRAKIPAEPVAQPCIASAVGSKMKLEDAKDSRTTNRFEQAVDGESGDLESSTGDDMAEMVTLSEDEATSPEGHSESSEGWSDTNLDPNELPSGSPMALEAMLIPLIQPIPHPSELGHIRTQSRVHDSSLPWMGLHKRKGLKVKKSMSAQAPL
What is the function of this protein?
No difference in cleavage specificity compared to isoform 1.
What are the official names of this protein?
Signal peptide peptidase-like 2C, SPP-like 2C, SPPL2c, Intramembrane protease 5, IMP-5.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein; Lumenal side.
Protein: DER_RALSO
Sequence: MKPVIALVGRPNVGKSTLFNRLTRSRDALVADMPGLTRDRHYGEGRVGERPFIAIDTGGFEPVAKEGIVAEMAKQTRQAVVEADVVIFIVDGRLGLAPQDRVIADYLRKTGRRILLAVNKAEGMKYTAVATDFYELGLGDPRAISSAHGDGVRELVDEALDLAFAERPELAEAAEGHDHGTRIAIVGRPNVGKSTLVNALIGEERVIAFDMPGTTRDAIYVDFERNGKPYTLIDTAGLRKRGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISDQDAHIAGFIVESGRALVIGVNKWDGLDGHARDRIKHDMERKLQFLSFANVHYISAKQRTGIGALMKSVDDAYAAAMVKLPTPKLTRVLQEAVEFQQPRRAGVSRPKLRYAHQGGSNPPIVVIHGNALSNIPETYRRFLEGRFRDAFQLKGTPLRIEFRTNKNPYAQSNE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: BPL1_MOUSE
Sequence: MEDRLQMDNGLIAQKIVSVHLKDPALKELGKASDKQVQGPPPGPEASPEAQPAQGVMEHAGQGDCKAAGEGPSPRRRGCAPESEPAADGDPGLSSPELCQLHLSICHECLELENSTIDSVRSASAENIPDLPCDHSGVEGAAGELCPERKGKRVNISGKAPNILLYVGSGSEEALGRLQQVRSVLTDCVDTDSYTLYHLLEDSALRDPWSDNCLLLVIASRDPIPKDIQHKFMAYLSQGGKVLGLSSPFTLGGFRVTRRDVLRNTVQNLVFSKADGTEVRLSVLSSGYVYEEGPSLGRLQGHLENEDKDKMIVHVPFGTLGGEAVLCQVHLELPPGASLVQTADDFNVLKSSNVRRHEVLKEILTALGLSCDAPQVPALTPLYLLLAAEETQDPFMQWLGRHTDPEGIIKSSKLSLQFVSSYTSEAEITPSSMPVVTDPEAFSSEHFSLETYRQNLQTTRLGKVILFAEVTSTTMSLLDGLMFEMPQEMGLIAIAVRQTQGKGRGPNAWLSPVGCALSTLLVFIPLRSQLGQRIPFVQHLMSLAVVEAVRSIPGYEDINLRVKWPNDIYYSDLMKIGGVLVNSTLMGETFYILIGCGFNVTNSNPTICINDLIEEHNKQHGAGLKPLRADCLIARAVTVLEKLIDRFQDQGPDGVLPLYYKYWVHGGQQVRLGSTEGPQASIVGLDDSGFLQVHQEDGGVVTVHPDGNSFDMLRNLIVPKRQ
What is the function of this protein?
Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, and methylcrotonyl-CoA carboxylase.
What are the official names of this protein?
Biotin--protein ligase, Biotin apo-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the biotin--protein ligase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: RLMH_STRP3
Sequence: MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTPDKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYSTITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITKGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_CAMLR
Sequence: MINKIEKEFIQHQKTLEQSLKLKEQIAMVAQELKVCLENGGKILICGNGGSAADSQHFAAELSGRYKKERKALAAIALSTDTSALSAIGNDYGFEFVFSRQVEALASDNDVLIGISTSGKSPNVIKAFEKAKEIGAKCIGLSGKGGGVMNALCEHNIVIPSDDTARIQEMHILIIHCLCDLIEEEY
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBP3_RAT
Sequence: MHPARPALWAAALTALTLLRGPPVARAGAGAVGAGPVVRCEPCDARALAQCAPPPTAPACTELVREPGCGCCLTCALREGDACGVYTERCGTGLRCQPRPAEQYPLKALLNGRGFCANASAASNLSAYLPSQPSPGNTTESEEDHNAGSVESQVVPSTHRVTDSKFHPLHSKMEVIIKGQARDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYDTKGKDDVHCLSVQSQ
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.  Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.  Promotes testicular germ cell apoptosis (By similarity).
What are the official names of this protein?
Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGO_KLEP3
Sequence: MFTYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHLMIALLCAVSDLLLICAGIFGGSALLMQSPWLLAIVTWGGVAFLLWYGFGALKTAFSQNLELASAEVMQQGRWKIIITMLAVTWLNPHVYLDTFVVLGSLGGQLAVEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINIVVGAVMWFIAFQLAKEGVGHILALLN
What is the function of this protein?
Involved in the export of arginine.  Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
What are the official names of this protein?
Arginine exporter protein ArgO.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1443_METJA
Sequence: MIFMGKTSLGLDENIEGALCYLFGVITGILFYILEKESKFVKFHAVQSIILFGGLWVLSIILAFIPYGWMLSGLVNLAAFILWIVCMYKAYKGEKFKLPVIGDIAEQYSQ
What are the official names of this protein?
UPF0132 membrane protein MJ1443.
What is the protein family that this protein belongs to?
Belongs to the UPF0132 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y7728_DICDI
Sequence: MITLRKSLSKSCKDLRILNGTTYVKGFCSTTTTDTTTTTSTSTTTDTDTNSEKSNKEKLFHQINELTKQSSFNKVLFYKKSAHETEGYSYKERQQFKQKQQKIKQIKHNQQLKQKQQIEQQKQKKLEQQQQQQQLELEKKQKFEQQLEQQQREQNQISLLEKSKDLESINDFGDFDFRELETKPLFSVPNVLINYLENEKTLSDHQKSDVVGSFYSDGEIPSVPHINLEEYTRSVLIEAYLEVCKPEYAFYYFKQSENNKTNSKGLLLMIEFYIKIGDIDSAFKFFEVNFKDYKDLISTNDYYKLFNGLITYSIDNQENIFDIKNKFFNVIINDNINNDIEKFNVGSLASMIESITPKYQPPPQEQQLMDDDSNSNSNNDSNNIIKNSSSKLEFNDDCVSNYKKLVNFDQLYSIYKNNYKKYTSDQRLIILSCILKYSIITADIELFLNTVNRVLVKDGIEKVEIPILQILFEAYTHTIPSDKPELVGQLKYLLTNYIKDMDSSDNGYKSISKLIAYNFSFKGDIKNSIYDQLCGIGIKSIEIDIENNIENSVLINKLKQEQREKERNQFIIFIQSIFPEDRIQHFVETALIYLINDNSYQEAVKLYIYFLKEGSVTGIDIFLKYHELSYKNIVYNNNNNNNNNNNNNNNNNNNNNNNNNIKNFTTFSENDHKTLKTFWERIKNNYVNNNNKQQQQEERDIENEFIFIGKGEINNDQLLEKFQYIKEFRNIKSFFNSYEENLNPNDFINYIKNIINKVNDDDNDNDNNNNNNNNNNNNNDDDDGGGHGGGDVFKTTTPKKVKPLISTIQKSQNELPTTTTYKEIIENTSFFRNQQYNFNRELSSTLNSPKSRLDLERLQSFLNCKSHTESMSFQQLCICLELVGDTGFKYDFYKNLNHIQKTLIITPQLCKNLFSTVTMDESIDILRRGLSRISPENLKSLGIWDGVFQGLLKDPLKTPLANFLMYNGFISKSSFDRYSYCQQIINTDIDAYYFFLDPSISYYDTFGGDIEDASNYNLKKDSSKTFFKPMEDFFITYLDTFFKASSPHEISQRPDYQTQFSNYTILSLIRLGKLNEAFKEIESLSPAKYNATTIGLVVFIYSKRYKQDKSKFLVEIQSLIQRIIFDLENKMGSEDARSYFHKYILKSLIINYGNIEMDNLIANVDVPKVLKDIDNSLAPNFDRRLIRKLFKVRGYIKYRFYRLN
What are the official names of this protein?
TPR repeat-containing protein DDB_G0287999.
Protein: BRE1_DROME
Sequence: MSKRSADDATGSSCLVAAAAAGQPPIKKVHFEPHLIGPVSTLEEMDIKVLEFQNKKLAQRIEQRMRTEAELRHRIEQLEKRQTQDDAVLNVVNRYWNQLNEDIRVLLQRFDAETADELENRNENEVTTSFLAQLSTWDKEELDEKLANRVQVSKRAVAKIVQVIDRLMQRNEKITHVLKGDSLASAGSGSGAGAGGEEEQQQASGDAETTTSSAGVHALEETLKQTHIEIMSENHKLQNLNTSLHEKFHTMSLKMKEYQDAHTAKETENAELKNQIDELQYDLEKIHCRNDKLENHLAEAIEKLKAYHQIYGDPNKSTNSAKTPTTTGSGGATTSVNSQLLEELQKELEEYRELANNRLQELDKLHATHRETLKEVEKLKMDIRQLPESVIVETTEYKCLQSQFSVLYNESMQIKTMLDETRNQLQTSKNQHLRQIEVMESEELIAQKKVRSEMIQMEDVLALIRKEYETLRIEFEQNMAANEQTAPINREMRHLITSLQNHNGQLKGEVQRYKRKYKDTSTDNLKLRQELADALATLEGNKLQAATGAAGEEIKQENSTGVKEENSNNVSASGQTNQTNSGNDTNVAIKEENHISAEDEADDEASGKDVKDGIKQEKLSSGDAAAAEKKDSPGPGNSTSSATNSVPVKNEKDSKDGVKGKDVKAVESETVRDLKAQLKKALNDQKEMKLLLDMYKGVSKDQRDKVQLMATEKKLRSEIEELRQQLKKLQESKREERKKLADEEALRKIKQLEEQKYELQKQMANHKPTDNSWGSGAPGTANYTRPFVGSHEEEALLNEMEVTGQAFEDMQEQNSRLIQQLREKDDANFKLMSERIKANQLHKLLREEKTVLEDQMATATTQIEAMHIVLRKLEEKERSLQATVASIEKELMLRQQAMEMHKRKAIESAQSAADLKLHLEKYHAQMKEAQQVVAEKTSSLEAEAYKTKRLQEELAQFKRKAERMKKMEMSGTTIDEVMIEEIREYKETLTCPSCKVKRKDAVLSKCFHVFCYDCLRTRYETRQRKCPKCNCAFGANDYHRLYLQ
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-117' of histone H2B.  H2B 'Lys-117' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation.  It thereby plays a central role in histone code and gene regulation.  Required for the expression of Notch target genes in development by affecting the levels of Su(H) in imaginal disk cells and stimulating the Su(H)-mediated transcription of Notch-specific genes.
What are the official names of this protein?
E3 ubiquitin-protein ligase Bre1, RING-type E3 ubiquitin transferase Bre1, dBre1.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEC2_ARATH
Sequence: MDNSDILMNMMMQQMEKLPEHFSNSNPNPNPHNIMMLSESNTHPFFFNPTHSHLPFDQTMPHHQPGLNFRYAPSPSSSLPEKRGGCSDNANMAAMREMIFRIAVMQPIHIDPESVKPPKRKNVRISKDPQSVAARHRRERISERIRILQRLVPGGTKMDTASMLDEAIHYVKFLKKQVQSLEEHAVVNGGGMTAVAGGALAGTVGGGYGGKGCGIMRSDHHQMLGNAQILR
What is the function of this protein?
Required for the female reproductive tract development and fertility.
What are the official names of this protein?
Transcription factor HEC2, Basic helix-loop-helix protein 37, AtbHLH37, bHLH 37, Protein HECATE 2, Transcription factor EN 117, bHLH transcription factor bHLH037.
What are the subcellular locations of this protein?
Nucleus.
Protein: EIF3M_DICDI
Sequence: MTIFIDLASLEDLYNDLISHIETLRKKKGSEYSVADYQILIGEQRTVEFLSKIVSNETEFLFKECKDSDKDIEGFFNVILTILHKLENEDEINIVSQKIRDSLSAHPTENSQLKIKILTNLFNSFQPKSTQRYDIFFALVKLASDSNNLEFVKYQITDIDSWLEDWNVSIQQKRKLYKLISNIFKEKQRMLSHQFLVKYLQTFTKEDSQEAQEDAVRVCIESISLQELYQSDYLLDLPAVQYLEGSTVSANSLTYELMKIFATEQLDSFLQFQQKNPNFLSTIGLSNDDCLQKIRLLSLATLTSEQSKVPYSLISKMLQIDENEVEMWVINAMEGDLLDAKLDQLNRIVNVNSSTQRVFNKSQWSQLGQRFSVWKSSVKNLLQVIENAKTTQVKPFYFQTR
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUPC_ECOLI
Sequence: MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLAWFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFISALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGKISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVDASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTGWFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIASTLSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLSASIAALVL
What is the function of this protein?
Nucleoside transport protein that can transport adenosine, uridine, thymidine, cytidine and deoxycytidine (PubMed:374403, PubMed:11466294, PubMed:14668133, PubMed:15678184).  Shows weak activity with inosine and xanthosine (PubMed:11466294, PubMed:14668133).  Transport is driven by a proton motive force (PubMed:374403, PubMed:14668133).  Does not transport guanosine, deoxyguanosine, hypoxanthine or uracil (PubMed:374403, PubMed:14668133).  Also shows activity with the chemotherapeutic drugs 3'-azido-3'-deoxythymidine (AZT), 2',3'- dideoxycytidine (ddC) and 2'-deoxy-2',2'-difluorocytidine (gemcitabine) (PubMed:14668133).
What are the official names of this protein?
Nucleoside permease NupC, Nucleoside-transport system protein NupC.
What is the protein family that this protein belongs to?
Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BAEB_BACVZ
Sequence: MDHTYEVHQIKTYHQMWSNYCYIIADRSKKSAIAVDPSWEIDKITDKLHELDVDLSAILLTHSHYDHVNLAEPLQQIYHSDIYMSSAEIDFYQFRCRNLIALEDGQTFAAGGFIIRSILTPGHTAGGMCYLLSDHLFTGDTVFTEGCGICGDRGSSAEDMFHSIQRIKASIPPHVRVYPGHSFGEKPGQKMESLLKNNIYFQIEKKEHFVNFRNRKNQKGLFHFK
What is the function of this protein?
Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
What are the official names of this protein?
Probable polyketide biosynthesis zinc-dependent hydrolase BaeB.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_HERAR
Sequence: MAKKKLNKNWLHDHINDPYVKLAQKEGYRARAVYKLKEIDESEKLIKPGQIIVDLGCTPGSWSQYVRNKLSGSVGGGINGIIIGLDMLEMEPIADVHYIQGDFREQNVLEQLEVVLAGRKVDLVLSDMAPNLSGIAVADAARMMDIIELAIDFAQHHMKPSGSLLVKCFNGSGFNDIVEKFRHEFKTVTQKKPKASRDKSSEIFLLGKTLKNPL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REP_BGYMV
Sequence: MPPPQRFRVQSKNYFLTYPRCTIPKEEALSQLQKIHTTTNKKFIKVCEERHDNGEPHLHALIQFEGKFICTNKRLFDLVSTTRSAHFHPNIQGAKSSSDVKEYIDKDGVTIEWGQFQVDGRSARGGQQSANDSYAKALNADSIESALTILKEEQPKDYVLQNHNIRSNLERIFFKVPEPWVPPFPLSSFVNIPVVMQDWVDDYFGRGSAARPERPISIIVEGDSRTGKTMWARALGPHNYLSGHLDFNSLVYSNSVEYNVIDDITPNYLKLKDWKELIGEQKDWQSNCKYGKPVQIKGGIPSIVLCNPGEGSSYKDFLNKEEKPALHNWTIHNAIFVTLTAPLYQSTAQDCQT
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep, 40.2 kDa protein, Protein AC1, Protein AL1.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: VPS72_PONAB
Sequence: MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVSTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPAPSASALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK
What is the function of this protein?
Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes.  As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 72 homolog, Transcription factor-like 1.
What is the protein family that this protein belongs to?
Belongs to the VPS72/YL1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGB_BACHK
Sequence: MSVINCEEVKRDEFHTEKYYESYNIFGAHIVTEDEMRGVRFTVWAPHAKAMSVVGDFNEWDYEQHKMLQVTEEGIWSLFIPHIEEREIYKYAIETMAGDVIFKADPYAVYAEVRPNTASVVFDIKGYEWNDKNWSRKKKKKSVYKEAMTVYELHFGSWKKKEDGTLYSYREMAEELIPYVVEHQFTHIEIMPLVEHPYDRSWGYQGTGYYAATSRFGTPYDLMHFVDECHKYGIGVILDWVPGHFCKDAHGLYLFDGTPTYEYKDKDVQENPVWGTVNFDLGKREVRNFLISNALFWMRYFHIDGFRVDAVANMLYWNKEGQEQSNEHAVSFLRELNEAVFAEDEDFLMTAEDSTAWPLVTAPTYEGGLGFNYKWNMGWMNDVLKYMECAPEYRKYIHDKMTFSLLYAYSENFILPLSHDEVVHGKKSLLNKMPGDYWDKFAQLRLLYGYFFTHPGKKLLFMGGEFGQFDEWKDLEDLDWNLHDFEMHRYMHDYFKELIALYKRSKPLWQLDHSREGFQWIDANNNEQSIFSFIRQGDKQEDALVVVCNFTKATYENYKVGVPDFEYYNEILNSDAEQYGGSGQVNKKRLKTIQEPYHNQTAHVEITIPPFGVSILRPVKTRKGSKKQDGSKTKVRSNVTSRGKR
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: TIG_RHIME
Sequence: MQVIETLAQGLKRELKVVIPADEMQARMNERLVEVKDRVRINGFRPGKVPVAHLKKVYGKSIMADLVNEIVREKPTEILTSRGEKSATQPEIAMTEDEAEADKILNAQADFEFTVAYEIIPPIELKDASGIKVTREVVDVSEDEVNEQIQRIAESARTYESKKGKAANGDRVTVDYLGKVDGEAFDGGKDEDAELVLGSNRFIPGFEEQLVGVKAGDEKTITVTFPADYPAANLAGKEATFDITVKDVAAAAPIEINDELATKLGLESVDKLKEIVRGQIESQFGSITRQKVKRQLLDQLDELYQFDTPERLVDAEFENIWRQINTDLQQAGKTFADEDTTEEEARAEYRKLAERRVRLGLVLSEIGEKAGVQVSDDEMQRSLFEQLRQFPGQEKEILEYFRNTPGAAASLRAPLFEEKVVDHLLTEVSVTDKKVSKEELTADDEGDEKPAKKTASKKKAAAKAEAGEGEEAAAPKKKAPAKKKAADESAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RLMF_CYTH3
Sequence: MAEKNKKEHPVTKDRLHPRNKHRERYDFDALIATTPELAQYVTLNIYNDQSIDFFNPAAVLCLNQALLKHYYGIDEWNIPEGYLCPPIPGRADYIHNIAALLGTSANDVIPVGPAIKCLDIGVGANCVYPIIGNNEYGWSFVGADVDPVSVASAKNIVDKNKVLQGNVEIRLQNHPLDIFYGIIGEGERFDVTICNPPFHASAEDAAAGTLRKLSNLQHKKVTKANLNFGGQHNELWCEGGESAFVREMILESKKFAASCLWFSTLISKQTNLQKAYDQLEVLAPFDVRTIPMGQGNKSSRLIAWTFQSKEAQAKWVSARWK
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_BEUC1
Sequence: MAATCDVCAKHPSFGYSVSHSHVRTKRRWNPNIQKVRTVVNGTPKRLNVCTSCLKAGKVTRAL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.