PharMolix/UniProtQA huggingface dataset:
Protein: RL28_STAAR
Sequence: MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: FIXA_ECO24
Sequence: MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: NDUS4_GORGO
Sequence: MAAVSMSVVLRQTLWRRRAVAVAALSVSRVPTRSLRTSTWRLAQDQTQDTQLITVDEKLDITTLTGVPEEHIKTRKVRIFVPARNNMQSGVNNTKKWKMEFDTRERWENPLMGWASTADPLSNMVLTFSTKEDAVSFAEKNGWSYDIEERKVPKPKSKSYGANFSWNKRTRVSTK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial, Complex I-18 kDa, CI-18 kDa, NADH-ubiquinone oxidoreductase 18 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=The interaction with BCAP31 mediates mitochondria localization.
Protein: MNME_BACCN
Sequence: MEFDTIAAISTALGEGAIAIVRVSGEDAIEKVNRIFKGKDLTAVSSHTIHYGHIVDLDTNQVIEEVMVSIMRAPKTFTREDIVEVNCHGGLVSVNKVLQLILAQGVRLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMNVAINQMEGRLSKLIGRLRQEILETLAHVEVNIDYPEYDDVEEMTHRILIEKATHVQNEIEKILETSKQGKILREGIATAIIGRPNVGKSSLLNSLVQEKKAIVTDIAGTTRDVIEEYVNVRGVPLRLIDTAGIRETEDIVEQIGVERSKEMMSQADLVLIVVNYSEPLTNEDEELFRAVQGKDFIVIVNKTDLPQKIEMERVTELASEKRVITTSLIEEKGVDELEKAIADLFFEGTIESADMTYVSNARHIGLLTQARKTIGDAIAAIENGVPIDMVQIDLTRTWEILGEITGDTVHESLIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCES_ASPFU
Sequence: MYDPARDSWEERDGDEARSCRGRLASDQPHAVFSPPEQIHGASGENNNTTDLQQHPDPSSKTTASAEVLYAESQPAQPTTQTPPSVSTRIQSPVDPAAQKASNPQSLTSTAQNQLNKSNTTMENTSGSATPKPRADPSDKPNRPVQVASPTDQNGSQGDKKRKLPAEENASEKSQPAPDRPVSKRKRMEERHQKLRKRGRTPPSAYSRRDAEETSSAADRNGPTYRSTSPLPPPRSPTPEDQPRQRKRPGGGARMGLVDRETLRRRQEERERAQVEEAMRASQSRGVADVVRQHYNAVPQRGREWRKTESKIKGLRSFNNWVKSTLIQKFSPDEEFLARFNGTKEWAEDGGVPPVEEKRLLVVDLGCGKGGDLGKWQLAPQPVDLYVGLDPAEVSIVQARERYNGMKSGRGNRGRRNPIFHAEFRPKDCFGEWLGDVDIVQQVGIDPNVGPGGSVMSSRWGGGGFDVVASMFTIHYAFESEEKARQMLRNVAGCLKKGGRFLGVCPNSDVISARVSEINAKKKARQAQAKKEKSDEAPEDGEVEEDDGKVEWGNQIYRVRFPITPPEDGVFRPPFGWKYSYFMEEAVEEVPEYVVPWEAFRALTEDYNLELQYRKPFLDIWRDEKDDPELGPLSERMGVRDRVTGKLLMTEEEKEAASFYHAFCFYKV
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSRP_YERPB
Sequence: MERCVFYISDGTAITAEVLGHAVLSQFPINVTTFTLPFVENAARAQSVCKQINEIYQDTGVRPLVFYSIISLEVREIIQRSEGFCQDIVQALVAPLQGELGVPPQPVLNRTHGLTESNLDKYDARIAAIDYALAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLQLPAALKPFQHKLFGLTINPERLAAIREERRENSRYASLRQCRMEVGEVEALFRKNQIRYLNSTNYSVEEISTKILDILGMSRRMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RS19_EMENI
Sequence: MGGVTVRDVDAQKFIVAYAAFLKRQGKLPIPGWVDTVKTSASNELPPQDADWYYVRAAAVARHIYLRKTVGVGRLRKVHGSTKNRGSRPAHHVDASGAVDRKVLQSLEKIGVLEQDEEKGGRRITQSGQRDLDRIAKTTVDEEEEDDE
What are the official names of this protein?
40S ribosomal protein S19, S16.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: RRN3_YEAST
Sequence: MMAFENTSKRPPQDFVAPIDQKKRKVQFSDSTGLVTLQPEEIKDEVFSAAMYSRFVKSALDDLDKNDSTQIGIIANQVALPSKNPERINDKNLNILLDILSSNINRIESSRGTFLIQSIINFEKWWELPPHTLSKYIYFIKILCSSIPKWWQDVSMILVSCFILPIKQTVCHHDMLKYFLRMIPSSMGFIDTYLAKFFPNKNDTRRKLVNYTSNLLKLRGYCSELGFQIWSLLIEKIISIDVELQNELDELDDDVDDDDLEEVDLEDDDDLDDDSGDDDDENCGNSNEELRSGAADGSQSDSEDMDIIEGMDGTEEYNVELTQGIKELSTKLDSILTLVSTHVEEQVTPESLESGEGVGVFNTLTTLFKTHVLPTYYTRSIQYIMFHVSQQQLELMDSFLVTLIDISFAVNEAAEKKIKSLQYLGSYIARAKKLSRTQIIFVASYLTSWLNRYVIEREEEVDQRGGMERFKHFYAAFQALCYIFCFRHNIFRDTDGNWECELDKFFQRMVISKFNPLKFCNENVMLMFARIAQQESVAYCFSIIENNNNERLRGIIGKADSDKKENSAQANTTSSSWSLATRQQFIDLQSYFPYDPLFLKNYKILMKEYYIEWSEASGEYESDGSDD
What is the function of this protein?
Required for efficient transcription initiation by RNA polymerase I.  Interacts with Pol I in the absence of template DNA and stimulates recruitment of Pol I, but does not remain as part of stable preinitiation complex.
What are the official names of this protein?
RNA polymerase I-specific transcription initiation factor RRN3.
What is the protein family that this protein belongs to?
Belongs to the RRN3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 5DNU_ECODH
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEIFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_BURM9
Sequence: MAGMKEIRGKIKSVQNTRKITKAMEMVAASKMRRAQERMRAARPYAEKVRAIAAHMSRANPEYRHPFMVANDGVKTAGMILVTTDKGLCGGLNTNVLRASLQKFKELEEQGQKVEATAIGGKGLGFLNRFGAKVISQVVHLGDTPHLDKLIGAVKTQLDLYSEGKLSAVYLAYTRFVNTMKQETVIEQLLPLSSEHFDANDGTPATSWDYIYEPDAQAVVDELLVRYVEALVYQAVAENMASEQSARMVAMKAASDNAKTVISELQLSYNKSRQAAITKELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y561_BORPD
Sequence: MTDQNHDTQADDDANDAPATDFSNQFLIAMPQMVEGSLAGSVIYVCEHTTRGALGLVINRPTDLTLESLFERIDLTLEIRPVKDSPVFFGGPVQTDRGFVLHAPAGDYSSSIKLGDLALTTSRDVLQAVADGNGPARMLVTLGYAGWGAGQLESEMAQNAWLTVGADADIIFDVPPEDRYPAALKLLGIDPVMLSGGAGHA
What are the official names of this protein?
UPF0301 protein Bpet0561.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL134_PLAVT
Sequence: MQGAYCVAVALLIAASGQAAANFGLEEPHQAPDSDFMASADTIDEMLQSRVLQVSHYPKDDLMLLAGNEERMLLARSNYLTKIPIPESIMTAANTMRMEGEASAIEAASKNVNQLRSNKRQPVASILNNVARHMSTTPDSDKFLVAVENDRPLVLAKRQRSAAITENGAKFAKQDDYRPVLSGPFTTNDEASNGRHNNQLFTLKALQLDKNENAGNVEDLWQEKKVSNRDLFHLLDEYENSAYLTVVSRLEANAIEAISKNSIRLESNKGKPIAPTPNIKVDQELYAPPDTGKSPVLVSTNIPYILAKRLKNEPPSAIIYNVAGFLAQHDYRPAPSGSSAISADAPNGQLDNQLITQKAFWLDKNKHIDDVESLFKEDTVEHLSHLREGNGESAHFTAVDRQSEPIVWPKDSAVFPQPQKKVVLNEEVNKVHEAFLKAFNLPFHQYLRETVTMLGIARWKRNSSPNSRAAISTLKIFAKNVDPKKLPKLLGTDFAKLQGDKKKHVA
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 134.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Localizes to bulk/chunk- like structures within the nucleus.
Protein: RS3_HERAR
Sequence: MGQKIHPTGFRLSVTRNWASRWYAGNSNFATMLNEDLKVRAYLKTKLKNASVGRVIIERPAKNARITIYSSRPGVVIGKKGEDIEVLKSALTKMMGVPVHVNIEEIRKPETDAQLIADSIAQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARKEWYREGRVPLHTLRAEIDYGFGEAETTYGIIGIKVWVYKGDRLPSGEPPVDLTKEDDTKRRGPRRDDGKPSSRPRTARPEGQPGAAAAPGAAPAAKRVRAKKPDAAVDGAVPAEKAGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: FEN1_CRYMR
Sequence: MGIKGLARFLVDNAPKSIQQQSIDSLIGRIIAIDASMWMYQFLAAIREGSQWGNLTNEAGESTSHISGMLSRTIRLLEAGIKPVFVFDGEPPELKMEELMKRKERREKAQQELEKAQEEGDTETIRKQLIRTIKITKEQSDDVKYMLKLLGIPVIEATSEAEAQCAELCKEGLVYGVATEDADSLTFGTPLVIRHLNFSDGKFSDSKGNSKNSLQVIKLSTVLSDLGLSMQQFVDLCILCGCDYCGTIRGIGALTAYKLLKKHKDIETIINELDKNKHPLPMSFDYIKVRELFTNPNVIKAKEFRDKLKWTNPNLEGLSEWLIKQQNFSEVRVANYCTRIKKSKGKTAQTSLDSFFTLTPKKTSENKNKEKEITKVQEVKETISNINKDTRKDSVSEWGEIKTKIIETKEDKLDFERRNKIIQEDKLNSKKEFDYNEKLQCNSTAENTPIIDNKAKVLSIKKRRINRVNYDE
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: CCA_THEAC
Sequence: MIDYQEVLSRYRPTQEEENKLKIISDDIIRKINSICRSRGLRAEAVIVGSYAKGTNLRDGDLDIFIAFDRDYPEEIINTEGLHIGHAVIPNGREKYAEHPYVSGEIGGVKIDVVPCYKMSFGDKKISAVDRTLLHTEYVNGHLDEKGRDEVRLLKIFTKSIGVYGAEARTFGFSGYLCELLVIRFGSFENVIRYFSKAKGRVLIDLDERFRDPMVLIDPVDPDRNVASPVSLESLSRMKIASKMFLSSPDEGFFQIEHNGKNVQYHDRGTCIMIYSLPKPDLTDDVIYPQVYRFRSVLQKIMESHEIRVISSEIDVSDRIYVLIETPACAEERIRVHTGPPVDTDNAVDFVNSWKARDRSRGPYIVADRLYVDVFTGQRSIEDIVRQEIFNYSIGKNLDRFKKSMEIMKFNVGMKSLPVLDKFFGADVFRK
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: RS10_AKKM8
Sequence: MQSPKIRIRLRAFDYRAIDRSSQEIVETAKRTGAKVHGPIPLPTRIEKFSVNRSVHVNKKSAEQFEIRTHKRLLDIVDPTARTIDELKKLNLPAGVDITIRI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RAG3C_ARATH
Sequence: MASRRRVLLKVIILGDSGVGKTSLMNQFVNRKFSNQYKATIGADFLTKEVQIDDRIFTLQIWDTAGQERFQSLGVAFYRGADCCVLVNDVNVMKSFENLNNWREEFLIQASPSDPENFPFVVLGNKTDVDGGKSRVVTEKKAKSWCASKGNIPYFETSAKDGVNVDAAFECIAKNALKNEPEEEVYLPDTIDVAGARQQRSTGCEC
What is the function of this protein?
Intracellular vesicle trafficking and protein transport.
What are the official names of this protein?
Ras-related protein RABG3c, AtRABG3c, Ras-related protein Rab73, AtRab73, Ras-related protein Rab7D, AtRab7D.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RHAM_LISMO
Sequence: MERVASIMYLYPGNKEEYKKRHDELWPEMKEALKAHGAANYSIFLDEKTDTLFAYVEVEDKAIYDKIAETEICQKWWKYMAPIMKSNPNNSPVAVDLKEVFYLA
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX13_ARATH
Sequence: MASQPAGGSPPKPWEKEGNTSGPNPFRPPSNTSTAGSVEASGTANPGEVVPPPVNRPNTAANMNSLSRPVPARPWEQQNYGSTMGGGYGSNLGMTSGYGSGTYGSALGGYGSSYGGGMYGGSSMYRGGYGGGGLYGSSGMYGGGAMGGYGGTMGGYGMGMGTGMGMGMGMGMGGPYGSQDPNDPFNQPPSPPGFWISFLRVMQGAVNFFGRVAMLIDQNTQAFHMFMSALLQLFDRGGMLYGELARFVLRMLGVRTRPRKMQQPPQGPNGLPLPHQPHGNQNYLEGPKTAAPGGGGGWDNVWGN
What is the function of this protein?
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (PubMed:16813573, PubMed:17478547, PubMed:19594707).  The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity).  Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (By similarity).  Essential for pollen-tube discharge that take place only in the presence of functional peroxisomes in either the male or the female gametophyte (PubMed:18160292).
What are the official names of this protein?
Peroxisomal membrane protein 13, ABSTINENCE BY MUTUAL CONSENT, Peroxin-13, AtPEX13, Peroxisome biogenesis protein 13, Pex13p, Protein ABERRANT PEROXISOME MORPHOLOGY 2, Protein AMC.
What is the protein family that this protein belongs to?
Belongs to the peroxin-13 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Peripheral membrane protein. Peroxisome.
Protein: UPPP_FERNB
Sequence: MKEFFLGIIQGLTEFLPVSSSGHLALFSKIISFPSDLALFAFFHIATFFAVFILLFNDIWNILYGLVRSDKNMWNLALKIIISSIPAGIVGLFFESKVEAAFSSQKLIGVFFLVTAAALWLSDKYSGNKTLNDITYLDALIVGLFQAIAVLPGISRSGFTLIGALLIGMTRVDAFKYSFLLSLPITLAAGLLELKNVDLTTATLSGFAGAFISGLVALILVRFVTISAHLKYFSIYLLIPAIVSFFMK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OOPDA_ARATH
Sequence: MLMATPTSRASLNLLRRSPKPKYFSSSSCHFRPSTFRKSYPCPIWSSSFSFCLPPPRSTTSTSLSSSSFRPFSSPPSMSSAAAAAVESVVSDETLSSNPLLQDFDFPPFDSVDASHVRPGIRALLQHLEAELEELEKSVEPTWPKLVEPLEKIVDRLTVVWGMINHLKAVKDTPELRAAIEDVQPEKVKFQLRLGQSKPIYNAFKAIRESPDWSSLSEARQRLVEAQIKEAVLIGIALDDEKREEFNKIEQELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSALGLFAQAAVSKGHENATAENGPWIITLDAPSYLPVMQHAKNRALREEVYRAYLSRASSGDLDNTAIIDQILKLRLEKAKLLGYNNYAEVSMAMKMATVEKAAELLEKLRSASWDAAVQDMEDLKSFAKNQGAAESDSMTHWDTTFWSERLRESKYDINEEELRPYFSLPKVMDGLFSLAKTLFGIDIEPADGLAPVWNNDVRFYRVKDSSGNPIAYFYFDPYSRPSEKRGGAWMDEVVSRSRVMAQKGSSVRLPVAHMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKQDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYETGETLPEEVYKKLLAARTFRAGSFSLRQLKFASVDLELHTKYVPGGPESIYDVDQRVSVKTQVIPPLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAFSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFRGREPSPEPLLRHNGLLAASASA
What is the function of this protein?
Oligopeptidase degrading short peptides from 8 to 23 amino acid residues.  Plays a role in the degradation of transit peptides and of peptides derived from other proteolytic events.  Does not exhibit a strict cleavage pattern.  Binds salicylic acid.
What are the official names of this protein?
Organellar oligopeptidase A, chloroplastic/mitochondrial, AtOOP, Thimet metalloendopeptidase 1, Zincin-like metalloproteases family protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Plastid, chloroplast stroma.
Protein: THIC_BACVZ
Sequence: MQNQSVQQANISIMSSFSGSKKVYAEGSSPDIRVPMREISLSATTGAFGEEENAPVRVYDTSGPYTDPDVQIDIHEGLGALRTKWITGRGDVEEYNGRIVKPEDNGYKKEDHAAEYPGLQRKPLRAKPGKNVTQLHYARKGIITPEMEFIAIREHVSPEFVREEVASGRAIIPSNVNHPESEPMIIGRNFHVKINANIGNSAVTSSIEEEVEKMTWAIRWGADTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGIAEDLTWDIYRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRTTGIVSRGGAIMAQWCLAHHQESFLYTHFEEICEIMKTYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMHKIKENMDKQLEICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNRDDVREGVITYKIAAHAADLAKGHPGAQIRDDALSKARFEFRWRDQFHLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISQDIRDYAKENGLTEDEAVNEGLKEKAKEFAEKGSRLYQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: VE7_HPV21
Sequence: MIGKEVTLQDIVLELNELQPEVQPVDLFCEEELPSEQQETEEELPERTAYKVVTPCGCCKVKLRIFVNATQFAIRTFQNLLFEELQLLCPECRGNCKHGGS
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: SIBC_DICDI
Sequence: MNKLFYLFILIASLFILTDASHFRFGTISWQPTTDYRTIKFTSNFAYRTTFFYSSTSSIKVGNLVNVGTLNFGSGVGSVTVSVTVTDFDVKNNWFTGTFTTTKAYPAQNSGTIREYTAIFTSCCRISSLLNNKDASWNITTSVQIDNKNELSMVNWSPVSGMIPIVQVVANKNNNFRVIASDQNVQNADSSALTFSFSKVYTMTQPSGMTIDSKGNCYFLPTQIGLYSTQIYILDSRGAYIVVDFILQSVAEPGTCDPTCSNAGTACNQNSQCKGCTNSGSTTIDTCTTSNYPPDFVSPPTPDDGDTKLFPIGASTSLTFSCKTIMSGRSTTIQTANLPVGVTTKTPVTGATSNTTITWTPTTANTGSYVVSLVCSDSTGLTSSVRSFTILVAKPDCGNGGYTESGVCKCVDNWDPASKCFECKDGYYGENCVAVPPCVNGVPNSGINGDGKCLCSNGWTGADCSISSSQSCKDLSNSNTSISYSNPSFVNPTKVQVYLTSTPNYEVPTIVSIPNPINNLDVYVLVDANLASTTAFGYIKSGMSTFVSNIENICETAQFGIGYFSDYTPSPISFSPSQVMGSPIAAAIGLYKPATYSTTSNGNSLLAATDAASASVGWNSGSFKVIVIITDSDHSSSSAQITAFTNKFIGKSIVPVVVSFGASSMTNWNSALTSAGFGSVVTASGTSASDWSAKANTGVKNVLSKIVYKSDPTATGSSFVSSVPSTVTVSSSSSTQQTVNGLKLSLPSGTTIVSPVATISAMGYGQTDISINYNRPPVATSGSFSVNQNSLATFKLTGTDPDANILQFKFTTFLTANAGVITDSNGKDVSKQQSNYYAASEIFTYTPFENYLASNTIRFVAFDGCVESNTYATISITINKVNQLPECSSISSTITTTLNTQSTFSMTATDFEDASPFLQFTKPTDLTAYGTFTYKGASITSSTKITTGDSVIFTQTVNPKNDATVTLEFRAIDTSNAFSQASCSVSFKIQHANVAPVSSSTSPISVIPRGSVSLTLVSTDSDSTKALFTITAIKNGNNGNFYTCSTNDCSCTSGSSDSTIISLKDQFSGISYSSTKANKLICFTNGEPSAISNYASISFTSTDDEGLESNTVSVVVNIVGDRANVAPVVTKIQDYSVYQDYLDSDAHVVTGTDADIDDYNPPNVNNLIAIITTPPSNGILVTVQNGNNVATQGNAPFTHYYRPNPGFKGTDSYSYQVMDTFKETSSVESTTVTVNPINHKPTLTVNSYSFTSQSGAGETQTLVTYDFDGDNVLCSVQAAPKQISMYDSENELITTLPKSLSSNSYSFKLLDASKISPTPFSSFSDSFIISCKDDSKLTTPYGVLSTGNVTGFVQFTYINTPPTTKGIQVELDQDTTEPFTFNGTDIESPSDLKAKIYALPANGQLLNGNVVLTSKLIGEETYELDALSYKPNAGLSNWNTIDNIGPLDSIPYSVVDQQGLVSDSDVVTFSVRPRNPPVYTGADVIDVLQNTRYPLNVQGKVGNGGSEVNIQVLKFSGRGTLSIAHSMGSEGTMDTEITSYPNSQTGSTSYNFAYMPPHNEYGNDFDFIEFKLFDGDLYSELYTITVNVIHVNQPPTIQLISYKVLDDTSKDNGEVLFDSTYIVNMNINTSVLIKYTGSDVDVDQVTPLLSTVTTALRGTLYTKDETVPDLKGSIIDRNHTTVEQSSDGYYYVVYSPVPDSSGNSYVRIPFFMTDNGGLDSPTLTAVINVNRYNIPPFVLAGNKTYSTTTKLALSVENVQFDDPDSGKSNNVSIVVSIVGENDENVASLEDIKISLKRMQNCELHTSLASISCLDTKSALNESIQTITVNAVTAGNYRLKLFVDDLGYNAPSAIRAQSHMNATGYVDVTFEEAETTTQTNDNKTVLTGAIAGAAAGTALIAAAAWRLLRKAAPPTDTFFSEAAFLGDGVSSNPLYEQSASAAENPLYQSASDTTD
What is the function of this protein?
Implicated in cellular adhesion.
What are the official names of this protein?
Integrin beta-like protein C.
What is the protein family that this protein belongs to?
Belongs to the SIB family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.