PharMolix/UniProtQA huggingface dataset:
Protein: NUOCD_BACFN
Sequence: MEEIKYIEPAALHDEMLRLRNEKQMDFLESLTGMDWGVADEGDAPNVTRGLGVVYHLESTVTGERIAIKTSTNNRETPEIPSVSDIWKAADFNEREVFDYYGIVFIGHPDMRRLYLRNDWVGHPMRKDNNPEKDNPLRMDNEETYDTTREIELNPDGTYQTQENVIFDDREYVVNIGPQHPATHGVMRFRVSLEGETIKKLDANCGYIHRGIEKMNESLTYPQTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSERVKYIRTIMDELQRIDSHLLFYSCLAMDLGALTAFFYGFRDREMILDMFEETCGGRLIMNYNTIGGVQADLHPNFIPRVKKFIPYLRGIIHEYHDVFTGNVIARQRLKGVGVLSREDAISFGCTGGTGRASGWACDVRKRMPYGVYDKVDFKEIVYTEGDSFARYMVRMDEIMESLNIIEQLIDNIPEGPIQEKMKPIIRVPEGSYYTAVEGSRGEFGVFLESHGDKTPYRLHYRSTGLPLVSAVDTICRGAKIADLIAIGGTLDYVVPDIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AFP_CULCO
Sequence: EWEPVQNGGSSYYMVPRIWA
What is the function of this protein?
Inhibits soybean trypsin.  Has antifungal activity against R. cerealis, A. brassicae and A. niger, and weak antifungal activity against F. oxysporum.
What are the official names of this protein?
Antifungal protein, Psc-AFP.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: CC138_MOUSE
Sequence: MERRVVKPPGQDMVVERLKSRYGLAGRCPVEENDMTGVWAALMNQQHELSDFDQTKYKRRIVTSPDGLDTYSSGDKVGSSPRYYSDGRNHPTPPFCSSFKHLNVNCLDDELDSFHDLKKWETEKELMEDDHRDGASKITKQSFKEMETDALMTSMASGLETECCSGSIDSPLKQAVYPRPKVSKKQGLLPHEINQIYDELYHIHMKLQYETTAQKKFAEELQKREQFLAEREQLLFSHETALSKIKGVKEEVLTRFQILKEQHGTEIEHLTEALKEKNKENKRMRSSFDTLRELNDNLRKQLNEVSEENKKMEIQAKRVQARLDNLQRKYEFMTVQRLKGDSHAAHEVKSSKQEKAPAPKPFKAALNGQVYELLTVFMDWISDCHLSKVEPEEPGVDGGKPPAKPSQRSDIQEKCVKLLPMMTEQLQWMPLVSAKLHEPFVRFIYWSLRQLDASARQSTMASTLRRLGEDVFKGVTMKGTQDNSLEHSVENKAKTAVFFKSSSLPLRFLSTLIVLRTVTQADYLAQAFDSLCLDLKTDEGKTLFLEYQAIPVILKHLRISSKGLLSNVIDSLLQMTVESKSLQPFLEACSNSLFFRTCSVLLRTPKLDLHILEKLSIILQKLSKIKSNKKLFEVFTIHLMLQEIQRTTHPEHAFLCINLNSTLFNLGLTKCNSLVTSTSH
What are the official names of this protein?
Coiled-coil domain-containing protein 138.
Protein: EFTS_BACFR
Sequence: MAVTMADITKLRKMTGAGMMDCKNALTDAEGDFDKAMKIIREKGQAVAAKRSDREASEGCVLVKVEEGFGAIIALKCETDFVAQNADFVKLTQDILDAAVANKCKTLEEVLALPMGDATVAQAVTDRTGITGEKMELDGYMVLEGATIAAYNHMNRNGLCTMVAFNKKVDEQLAKQVAMQVAAMNPIAVDEDGVSEEVKQKEIEVAVEKTKVEQVQKAVEAALKKANINPAHVDSEDHMESNMAKGWITAEDVAKAKEIIATVSAEKAANMPEQMIQNIAKGRLAKFLKEVCLLNQEDIMDAKKTVREVLKEADPELKVVDFKRFTLRAE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG_ASPTN
Sequence: MTALQQFSRDGTFLSEALQTPISMNIWNTHYNKDFFPGPTEFWPERWMGEGTRELEKYLVPFGSGSRMCTGQNLSIAEQVLTIATLFRNYELELYQTTKKNVVMASYCMISLPGSESPGIQVKVRKTVQ
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase (BTK) (PubMed:24534845, PubMed:25265334).  The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the 6-methylsalicylic acid synthase atX (PubMed:9003280, PubMed:9438344, PubMed:25265334).  In the biosynthesis of 6-MSA, atX utilizes one acetyl-CoA and three malonyl-CoAs as its substrates and catalyzes a series of programmed reactions including Claisen condensation, dehydration, reduction, and cyclization to yield 6-MSA (PubMed:9003280, PubMed:9438344, PubMed:25265334).  The 6-methylsalicylic acid decarboxylase atA then catalyzes the decarboxylative hydroxylation of 6-MSA to 3-methylcatechol (PubMed:25265334).  The next step is the conversion of 3-methylcatechol to terremutin via several oxidation steps involving the cytochrome P450 monooxygenase atE and probably also the cytochrome P450 monooxygenase atG (PubMed:25265334).  Lastly, atC is required for the oxidation of terremutin to terreic acid (PubMed:25265334).  No function could be assigned to atD yet, although it is involved in the biosynthesis of terreic acid (PubMed:25265334).
What are the official names of this protein?
Cytochrome P450 monooxygenase atG, Terreic acid biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: PIG17_CLAP2
Sequence: MASITTTTNFFESIPRPTKTYRSASYDRISTRHGFNGTGKTVLITGGSSGIGLSIAKAFAGAGVARIAILSRSRATQLTAKAEIEAAYPSTSILLFEASVTDADRFASVLEELAGVHVLVLCAAAVHARVPLAELSGKDVQHVFDTNSVSTVNLARLYTATPGKDKTILHVSSAVAQMYAPLRSVYGASKAAAVQAMQHLAREHQGTGDRVRVFSFHPGAITTPASGAIYTPGAVQWDDADLPAHFSLWLAGPESDFLNGRYVWANWDVDELVALKERLACDGRFLTIGLVL
What is the function of this protein?
Short chain dehydrogenase/reductase; part of the ergochrome gene cluster responsible for the typical purple-black color of the ergot sclerotia (Probable).  The ergochrome gene cluster produces several ergot pigments including the yellow ergochrome secalonic acid and its derivatives, as well as the red anthraquinones endocrocin and clavorubin (PubMed:28955461).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) CPUR_05437 (By similarity).  The atrochrysone carboxyl ACP thioesterase CPUR_05436 then breaks the thioester bond and releases the atrochrysone carboxylic acid from CPUR_05437 (By similarity).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (By similarity).  The next step is performed by the anthrone oxygenase CPUR_05434 that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving CPUR_05427, CPUR_05428, CPUR_05429 and CPUR_05430 (By similarity).  The short chain dehydrogenase/reductase CPUR_05418 then catalyzes the C-5 ketoreduction to give the xanthone skeleton of the monomeric units (PubMed:32105084).  Ergochromes formation requires further dimerization steps of different xanthone units, probably catalyzed by the cytochrome P450 monooxygenase CPUR_05419 (PubMed:28955461).  CPUR_05425, CPUR_05426 and CPUR_05431 are unique to Claviceps, thus it is likely that they are involved in further modification of xanthone units or in their dimerization (PubMed:28955461).  The yellow ergochromes and the red anthraquinone pigments endocrocin and clavorubin are products from the same PKS derived precursors and the latter are likely shunt products in the pathway of xanthone biosynthesis (PubMed:28955461).  It is proposed that atrochrysone carboxylic acid released from the PKS CPUR_05437 can also be converted to endocrocin anthrone which is further oxidized into endocrocin by CPUR_05435 (By similarity).  Endocrocin could be then modified to clavorubin, possibly by CPUR_05423 and CPUR_05431 (PubMed:28955461).  Clavorubin is the principal anthraquinone metabolite produced by the cluster with a much higher yield compared to endocrocin (PubMed:28955461).
What are the official names of this protein?
Short chain dehydrogenase/reductase CPUR_05418, SDR CPUR_05418, Ergochrome biosynthesis cluster protein CPUR_05418.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RS6_LARHH
Sequence: MRHYEIVFIVHPDQSEQVPAMVERYKGMVLGQNGKIHRLEDWGRRQLAYPIQKIHKAHYVMMNIECGKETLEEIEHAFKFNDAVLRHLTIKMDRAVTEASPMMKEEKAKNLLAPQSDAAEPTAAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SAP_MOUSE
Sequence: MYALALFASLLATALTSPVQDPKTCSGGSAVLCRDVKTAVDCGAVKHCQQMVWSKPTAKSLPCDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNPGEVCSALNLCQSLQEYLAEQNQKQLESNKIPEVDMARVVAPFMSNIPLLLYPQDHPRSQPQPKANEDVCQDCMKLVSDVQTAVKTNSSFIQGFVDHVKEDCDRLGPGVSDICKNYVDQYSEVCVQMLMHMQDQQPKEICVLAGFCNEVKRVPMKTLVPATETIKNILPALEMMDPYEQNLVQAHNVILCQTCQFVMNKFSELIVNNATEELLVKGLSNACALLPDPARTKCQEVVGTFGPSLLDIFIHEVNPSSLCGVIGLCAARPELVEALEQPAPAIVSALLKEPTPPKQPAQPKQSALPAHVPPQKNGGFCEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILVEVMDPGFVCSKIGVCPSAYKLLLGTEKCVWGPSYWCQNMETAARCNAVDHCKRHVWN
What is the function of this protein?
Saposins are specific low-molecular mass non-enzymatic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
What are the official names of this protein?
Prosaposin, Sulfated glycoprotein 1, SGP-1.
What are the subcellular locations of this protein?
[Prosaposin]: Secreted. Note=Secreted as a fully glycosylated 70 kDa protein composed of complex glycans. SUBCELLULAR LOCATION: Lysosome.
Protein: Y4TO_SINFN
Sequence: MTISRRDLFKAGLAAGAALSVPSLLRAQTAVAADKTVRMALENLSVFDPVATTAGISQTHALAIYDTLFSADSQSQPHPQMVGNWGVSDDKKTYTFELRDGLGWHDGTPVTAADCVASIRRWAQVGSGGQILMSRASDISKKDDRTFVISLKEPLGALPSILAFEGPFIMREKDAGLPPTEQVTANIGSGPFKFNHDLAKPGASFTYDRNEKYVPRKEPPDGMAGGKTVYVDRVVWDIGVLADPQTSVAALQTGEIDFLYRPPIDLLPLIESDPNLKLEALNRAGVDMTLRMNCLQAPFNSVKARQALLHLVDQEAVLRAAYGNPQYFKPVTSMFGNTAAVTNDENTGWFKPGGDPEKAKQLFKEAGYAGEKIVILQATDWAEQSNASQVVAAKLREIGVNAELAPSDWGGLVSRRSKRDSVDNGGWSIFITDQSEATRANVFTDISLAMNGEKAWYGWPKNDEYEALRAKWLTLETLDERKALAREMQKLWWDYVPEVPLGQNIVPSAYSKTLTGLIPATLPLMWNMQKA
What is the function of this protein?
Probably part of the binding-protein-dependent transport system y4tOPQRS for a peptide.
What are the official names of this protein?
Probable peptide ABC transporter periplasmic-binding protein y4tO.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: IF12_BURPS
Sequence: MAKDDVIQMQGEVIENLPNATFRVKLENGHVVLGHISGKMRMHYIRILPGDKVTVELTPYDLSRARIVFRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_PROMP
Sequence: MRSIKLHRLLDLVGIIPSLDLIDKEINNISFNSKEVQKGTLFLGMPGLNVDGGKYCIEAIENGAEAAIIGSAAKQKIGSIDRERILVIEDNLDYIFGQIVSEFWNRPSRKLKLIGVTGTNGKTTITFLLEYLLKKLGKKTALFGTLFNRWPGFSEVASHTTDFADKLQKKLNAAVDAESEFAILEVSSHSIAQNRISGCEFEAAIFTNLTQDHLDYHSDMESYFQTKRKLFFPPYLKDKDGISVLNHDDLWISKLSSDLEKRSSLVSTKITKSEFKNDGFFYVTDKQFTESGSTCIFHTPKEKIKLFVPLVGEFNLMNAIQAITILYKLNFSLKDLSKLIQSFPGAPGRMEKIEIDNNDVSRSLPIVIIDYAHTPDGLKKVLQSIKKLCKGKLITVFGCGGDRDRSKRPLMGSIAEEFSDHVFITSDNPRSEEPQQIVNDILMGIEKREKITFDIDRFKAINESIKFANKEDIVLIAGKGHEDYQILNDKVINFDDRKIAQKLLQEKSKSK
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRP1_YEAST
Sequence: MMEKEGKKPERHMDNILKMSIPVKSMSEVSRPGSAALGNTDAMRASLRNSRRSFSGHVRLVLRLVYGFISAVIIAGSPLRDRVCFQITGKGQAKQSDVWVIPAMPVYVSPFQEACFVFSPSAMVT
What are the official names of this protein?
Uncharacterized protein BRP1.
Protein: ENO1_LACLS
Sequence: MTVTIENIHAREIFDSRGNPTVEVDVRLTDGTLGRAAVPSGASTGDREAVELRDGGARLQGKDVSKAVANVNGEIYEALKGQSPFNQAKLDHLMIELDGTKNKSRLGANAILGVSMAIARAAANSEKIPLYRYLGGVDLELPQPFFNVINGGVHADSGIDVQEFLITPVKRASFRDGLEKIANIYHTLKKILADKGLETAVGDEGGFAPKLGSTENAIATLYQAIERAGYVPGEEIAIAIDPASSEFYDDKEKVYHFEGQKLTSAELLTYYEGLVEKYPALISIEDGFSEHDWAGFAAQTKVQGQKIQLVGDDIFVTNPEIFKEGIQKGVANAILIKLNQIGTVTEAIEAISLARKAGYKTMISHRSGETVDSFIADFAVAMHAGQIKTGSMARSERVEKYNQFLRIEEELLGLEVTK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 1, 2-phospho-D-glycerate hydro-lyase 1, 2-phosphoglycerate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: DTLB_XENLA
Sequence: MLFRSVVNKPRFGCGHNGAPFTSPLQSLLQCYQCVKQDEHISYGDLGRAVPPFGCAFSTVPGMSHVLAVANEEGIVRLYDTECGDMQRLVVKEFMAHTNAVFDIAWVPGEHKLVTASGDQTAKLWDVKAGELIGECKGHQCSLKSVAFSKFERAVFSTGGRDGNIMVWDTRCNKKDGFYRQVNQITGAHNAIDKQTPSKVKKRKPSIRGLAPSVDSQQSVTVVIFQDEYTVISAGAVDGVVKIWDLRKNYSTYRQDPVPVKLFPYPGNSTRKLGYSSLVLDPTGTNLFASCTDDNVYMFNATGLKTDPVSVFRGHQNSTFYIKASVSPDGQFLLSGSSDHSAYIWQVSDPLAAPINLIGHCQEVTSVAWCQSDFTKIATCSDDNTVRIWRLNRSSEDSSESNKTDYVGWACKKKFEPSSMAAILCTPGKPSMIPSSSLMSSPTPATCAPSNTGDLPLPSSTPLSALLPTSKLQTPKRINNGGLGASPKQMSSSKISIKDWVTRTPKSSKGTDSKTPSPRKAFTPVEQYPIVSNARVQLPYEKRAKRRLETSSEDVEHVCLDNCCVMELEPRLKKSKLDLCSLNERDCRDDKCLRLSDLSKEFDQELSPSPSTSLHMNATDNPPTLSPLSEMKSDFVDKENSSPEKNWLSALGHKFKSDNSSPQFKSSSSPSSRNSTSKKHQPRNAPNSPVSVPTTPGSMRKICTYFFKKSE
What is the function of this protein?
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis.  The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2.  CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication.  CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing.  KMT5A degradation is also important for a proper regulation of mechanisms such as TGF-beta signaling, cell cycle progression, DNA repair and cell migration.  Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation.  In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.  May play a role in the regulation of the circadian clock (By similarity).
What are the official names of this protein?
Denticleless protein homolog B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat cdt2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome.
Protein: SYGB_ERWT9
Sequence: MTDKTFLVEIGTEELPPKALRSLAESFAANLTAELDAAGLAHGEVSWFAAPRRLALKVANLSAAQPDREVEKRGPAIQAAFDANGVATKAAEGWARGCGITVDQAERLSTDKGEWLMYRARVTGERTQVLLPAMIATSLAKLPIPKLMRWGASEVQFVRPVHTVTLLLGDELIPANILGIDSARIIRGHRFMGEPEFTIDHADQYPQILLERGKVQADYAARKAIIKADAEAAAAKIGGVADLSDSLLEEVTSLVEWPVVLTATFEEKFLAVPAEALVYTMKGDQKYFPVYDKAGKLLPNFIFVTNIESKDPQQIISGNEKVVRPRLADAEFFFNSDRKRRLEDNLPRLETVLFQKELGTLRAKTDRIQALAGWVAAQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDELPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLPLDLQTLTEEAVRLYGSKLSNAKAVDEVVDFMLGRFRTWYQEEGHSVDTLQAVLARRPTRPADFDARMKAVSHFRTLEQAASLAAANKRVSNILAKATEPLNDSVQASLLKENEEIKLATYVTALSSKLQPFFAEGRYQDALIELAQLREAVDNFFDKVMVNAEEKEVRINRLTLLAKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAKD4_MOUSE
Sequence: MAVRLMKRCTCLLREATRLVPTVAPVGRLRLAGVSCKTLTSSVSSPSSGSLAELLGKEQVFTPYPEHQELDFLIEKASRPEQLLELLGSDHSLHHNHAALILIRLSYLLSEKPKEKALLAEDARFQRLVKLVDSQITCVWHGTLVKLLRSLYTLVLPQISKELQSVEQEVRWRLRRLKYKHLVFLAESCASFMKEQHSQELLAELLMHLERRWTEINDSRTLVTMMTMAGHLSESLMNHLEDKCLELVEQFGPDELRKVLVTLAAQSRRSVPLLRAISYHLVQKPFPMTKGMLLDLAYAYGKLSFHQTQVSQRLAADLLPFIPSMTPGEVARCAKSFAFLKWLNLPLFEAFTQHLLSRVQDVSLSHVCSVLLAFARLNFHPEQEEDQFFSMVHEKLDPVLGSLEPALQVDLVWALCVLQHVHETELHTVLHPGLHARFLESKSPKDQSTFQKLVHINTTALLEHPEYKGPFLPASAVAPIPSPSNKKMTPLQKELQETLKALLGNTDKGSLEVATQYGWVLDAEVLLDADGHFLPLRNFVAPHLAQPVGNQPLPPGAKRIAFLRWEFPNFNSRSKDLLGRFVLARRHVLAAGFLVVDVPYYEWLDLKSEWQKSAYLKDKMRKAMAEELAK
What is the function of this protein?
Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species, such as MT-CO1, MT-CO2, MT-CYB, MT-CO3, MT-ND3, MT-ND5 and MT-ATP8/6.  May play a role in cell cycle progression.
What are the official names of this protein?
FAST kinase domain-containing protein 4, Protein TBRG4, Transforming growth factor beta regulator 4.
What is the protein family that this protein belongs to?
Belongs to the FAST kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ATPA2_LISMF
Sequence: MSIKAEEISSIIKQQIENYQSELKVSDVGTVTYIGDGIARAHGLDNAMAGELLEFSNGVMGMAQNLETNDVGIIILGPYTEIREGDEVRRTGKIMEVPVGEALIGRVVNSLGQPVDGLGPIETTGTRPIEAVAPGVMQRQSVNEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAIDTILNQADQDMICIYVAIGQKESTVRNAVETLRHHGALDYTIVVTAAASQPAPLLYLAPYAGVAMAEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDSLGGGSITALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQIKAMKTVAGTLRLDLAAYRELESFSQFGSDLDAATRAKLERGKRTVEVLKQDLHKPLKVEKQVLILYALVHKYLDDVPVHDVLRFESEMNTWFDHNHPELLEEIRTTKKLPDEAKLEAALKEFKNTFVPSEEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL6_METCA
Sequence: MSRVANNPISIPKGVEVTIADGIVTAKGKNGLLSRTVPAELGVDLEGGTLSIRYNKNDQRQNALAGTTRANLANMIVGVSNGFERKLSLVGVGYRAQAKGDVLSLSLGFSHPVEFKVPAGVVVETPSQTDIVVKGADRQVVGQVAADIRAFRAPEPYKGKGVRYADEVIIRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HIS3_GEODF
Sequence: MIKIDFDKMGGLIPAVIQDYQSGEVLMVAFMDQKTLDLTLKDGKTWFFSRTRNKYWMKGEESGNTQEVMEVLTDCDADTVVIKVKQNGPAACHTGNRSCFYVKWEDGQWVEHSNPLFDPNEVYKKG
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATCA2_ARATH
Sequence: MDKISIRCFIFLVLTSFVTTVSCLSAATDYREVEDEHEFSYEWNQENGPAKWGKLRPEWKMCGKGEMQSPIDLMNKRVRLVTHLKKLTRHYKPCNATLKNRGHDMMLKFGEEGSGSITVNGTEYKLLQLHWHSPSEHTMNGRRFALELHMVHENINGSLAVVTVLYKIGRPDSFLGLLENKLSAITDQNEAEKYVDVIDPRDIKIGSRKFYRYIGSLTTPPCTQNVIWTVVKKVNTHRYFLLFFT
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Alpha carbonic anhydrase 2, AtaCA2, AtalphaCA2, Alpha carbonate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the alpha-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Note=Targeted to the chloroplast via a protein-targeting pathway that uses the secretory system.
Protein: ARGC_ENDTX
Sequence: MVRTGIVGITGYTGEELLRILSKHPNVKITGLYGRSSSEKRHLKDIYPHFNCLDLRVEALNVKQIANICDVVFLALPHAVAFEVVPHLIDAGVKVIDLSADFRLVRPEVYERWYNVKHTAKEYIGKSVYGLSELNTEKIKRALLIANPGCYPTTVILGCAPAVKNGFIDLRGIVIDSKSGISGSGRKSAQAYFKDEHPNFRAYKVAGEHRHIPEIEQELSVLSGEDVTISFTPHIMSVERGMLSTIYINMKKQIATSAIIEKYRKFYSGRHFIKILDENVILGIKDVLNTNYCEISMKVDERTNKLIIVSVIDNLVKGASGQAVQNMNIMFGLPETAGL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_CHLL3
Sequence: MMKKAEDPLQDREGTIQEHTEGQAGTAAADQSAAVETPESRIAGLEREVQAEKEQNGKFRDELLRRAAEFENFRKQKEREAVMASQRATDNVLRDLLTLVDDVERVLANVPEPEEIPAAAKPYIDGVELLKKNLDRWLESKGVKPIEAIGMKLDVDFHEAISQIEHPDAEPETIVEQYQTGYLLGDRVLRHAKVIVAR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_KOCRD
Sequence: MNGKRIQATGATLRVKQVRSVVGQKQNMRDTLRSLGLKRPGQVVERKADAATVGMINTVTHLVEVEEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.