PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_SALPC
Sequence: MVEDSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRMVGETGKVILADINDSMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTEKEKALRSMFRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHILPRIGSMVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PLAS_ULVAR
Sequence: AQIVKLGGDDGALAFVPSKISVAAGEAIEFVNNAGFPHNIVFDEDAVPAGVDADAISYDDYLNSKGETVVRKLSTPGVYGVYCEPHAGAGMKMTITVQ
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the inner thylakoid membrane surface in chloroplasts (By similarity).
Protein: YIFK_SALTY
Sequence: MAEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTTIIVMIIIGLGVIFFGFGNGGQAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAVAKVSRHGVPVAGVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKEAIADHPFRSIMFPWANYLTMAFLVCVLIGMYFNEDTRMSLFVGVIFLLAVTLVYKVFGLNRHGTAHKVGE
What is the function of this protein?
Probable amino-acid or metabolite transport protein.
What are the official names of this protein?
Probable transport protein YifK.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_XANC8
Sequence: MDVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEELDEVPDDATVIFSAHGVSQAVRVEAERRGLKVFDATCPLVTKVHFEVARHCRAGRDVVLIGHAGHPEVEGTMGQWSRERGPGQIYLVEDIEQVATLQVRQPENLAYTTQTTLSVDDTMGIIEALRVRYPAMQGPKHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRDGVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGANGVSELAGEPESMVFALPKELRLRLVS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: CLPS_BURCH
Sequence: MAIIPDKQDSTVLERKQQKLKPPSMYKVVLLNDDFTPMEFVVMVVQEYFKKDRETATQIMLKVHREGRGVCGVYTRDIASTKVEQVVTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: FAED_NEUCR
Sequence: MAGLHSRLTTFLLLLLSALPAIAAAAPSSGCGKGPTLRNGQTVTTNINGKSRRYTVRLPDNYNQNNPYRLIFLWHPLGSSMQKIIQGEDPNRGGVLPYYGLPPLDTSKSAIYVVPDGLNAGWANQNGEDVSFFDNILQTVSDGLCIDTNLVFSTGFSYGGGMSFSLACSRANKVRAVAVISGAQLSGCAGGNDPVAYYAQHGTSDGVLNVAMGRQLRDRFVRNNGCQPANGEVQPGSGGRSTRVEYQGCQQGKDVVWVVHGGDHNPSQRDPGQNDPFAPRNTWEFFSRFN
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin (By similarity).  Active against methyl esters of ferulate (MFA), sinapate (MSA), caffeate (MCA) and p-coumarate (MpCA) (PubMed:14595525).
What are the official names of this protein?
Feruloyl esterase D, Ferulic acid esterase D, FAE.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURT_SHEAM
Sequence: MIGTPYTQGATRAMLLGSGELGKEVAIELQRLGVEVIAVDRYPNAPAMQVAHRSHVINMLDGEALKALIASEKPHLVIPEIEAIATQTLVELEAEGLKVVPTARATRLTMDREGIRRLAAETLALPTSPYVFCDSLTELQAALKVTGIPCVVKPVMSSSGKGQSVIRSPGDVQKAWDYAQSGGRAGEGRIIVEGFIDFDYEITLLTISAVDGIHFCAPIGHRQEDGDYRESWQPQAMSSLALDRAQHIAREVVQNLGGFGLFGVELFIKGDEVYFSEVSPRPHDTGMVTLISQDLSEFALHVRAILGLPVGTIVQRGPSASAVILVEGESSNIGYSGLAEALAQPNTQLRLFAKPEIHGRRRLGVALARGTSIDEALQTALASAGCIKVHFN
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: NUOK_ECOLU
Sequence: MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDTK_YERPB
Sequence: MQKYIVEARSLLALAIPVVIAQLSQTAMGVVDTIMAGSVSATDMAAVAVGTSIWLPAILFGHGLLLALTPTVAQLNGSGRRSQIAHQVRQGFWLALCVSVLIMLVLYNSDHVIKQMDNIDPVLAQKAVGFLHAIMWGVPGYLFFQVLRNQCEGLSKTKPGMVIGFVGLLVNIPINYIFIYGKFGAPALGGVGCGVATASVYWVMFLMMRWYVTRARSQQDIKLEKGFAAPDWQVMKRLSGLGLPVALALFFEVTLFAVVALLVSPLGIVAVAGHQIALNFSSLMFMLPMSLSVAATIRVGFRLGQGAVEQAQVAAYTSMAVGLLLASVTAVFTIVFREHIALLYNKTPEVVTMASHLMLLAALYQLSDAVQVIGSGVLRGYKDTRSIFFITFTAYWLLGLPSGYLLGLTDYILPAMGPAGFWIGFIIGLTAAAILMVLRIRWLQKQPTAFILQRAAH
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM3_PROMT
Sequence: MTLDQLRIASRRSQLAMVQTNWVRDELQREHPDLVITIEAMATQGDKILDVALAKIGDKGLFTKELEAQMLLGHAEIAVHSLKDLPTNLPDGLILGCITKREDPSDALVVNEKNQIHKLETLPEGSVVGTSSLRRLAQLRYHYPHLVFKDVRGNVITRLEKLDSGEYDCLILAAAGLQRLGFANRIHQLIPTDISLHAVGQGALGIECVSGQQKVLDILKTLEHESTSKRCLAERSFLRELEGGCQVPIGVRTEINNNELILEGMVASLDGKRLIRDIKKGSVSSAEEIGIDLANELKGRGAGEILEEIFKSARA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: BETA_PECCP
Sequence: MEYDYIIIGAGSAGNVLATRLTEESDVSVLLLEAGGPDYRLDFRTQMPAALAFPLQGKRYNWAYETDPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNAMDFDNWATMPGLEDWSYLDCLPYFRKAETRDVGSNDYHGATGPVSVATPKMGNNELFHAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPKGRRASTARGYLDQAKGRKNLTIVTHALTDKILFEGKRAVGVAYFKGESPQTVQARREVLLCAGAIASPQILQRSGVGPKDLLQGLDIPVVHDLPGVGENLQDHLEMYLQYACKEPVSLYPALQWFNQPKIGAEWLFSGTGIGASNQFEAGGFIRSRDEFAWPNIQYHFLPVAINYNGSNAVKEHGFQAHVGSMRSLSRGRVQVRSKDAREHPSILFNYMSTEQDWQEFRDAIRITREIMAQPALDKYRGREISPGLEVQTDEELDEFIRTHAETAFHPSCSCKMGEDEMAVVDGQGRVHGMEGLRVVDASIMPQIITGNLNATTIMIAEKIADRIRRRQPLPRSRARYYVSGNTPVRKAPLKPAS
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: GB_EHV1
Sequence: MSSGCRSVGGSTWGNWRGDGGDLRQRRVLSPVCSAPAAGSWIGSQLGNVGNLLATPHPLGKPASSRVGTIVLACLLLFGSCVVRAVPTTPSPPTSTPTSMSTHSHGTVDPTLLPTETPDPLRLAVRESGILAEDGDFYTCPPPTGSTVVRIEPPRTCPKFDLGRNFTEGIAVIFKENIAPYKFRANVYYKDIVVTRVWKGYSHTSLSDRYNDRVPVSVEEIFGLIDSKGKCSSKAEYLRDNIMHHAYHDDEDEVELDLCRPSLQLRGARAWQTTNDTTSYVGWMPWRHYTSTSVNCIVEEVEARSVYPYDSFALSTGDIVYASPFYGLRAAARIEHNSYAQERFRQVEGYRPRDLDSKLQAEEPVTKNFITTPHVTVSWNWTEKKVEACTLTKWKEVDELVRDEFRGSYRFTIRSISSTFISNTTQFKLESAPLTECVSKEAKEAIDSIYKKQYESTHVFSGDVEYYLARGGFLIAFRPMLSNELARLYLNELVRSNRTYDLKNLLNPNANNNNNTTRRRRSLLSVPEPQPTQDGVHREQILHRLHKRAVEATAGTDSSNVTAKQLELIKTTSSIEFAMLQFAYDHIQSHVNEMLSRIATAWCTLQNKERTLWNEMVKINPSAIVSATLDERVAARVLGDVIAITHCAKIEGNVYLQNSMRSMDSNTCYSRPPVTFTITKNANNRGSIEGQLGEENEIFTERKLIEPCALNQKRYFKFGKEYVYYENYTFVRKVPPTEIEVISTYVELNLTLLEDREFLPLEVYTRAELEDTGLLDYSEIQRRNQLHALRFYDIDSVVNVDNTAVIMQGIASFFKGLGKVGEAVGTLVLGAAGAVVSTVSGIASFLNNPFGGLAIGLLVIAGLVAAFFAYRYVMQIRSNPMKALYPITTKALKNKAKTSYGQNEEDDGSDFDEAKLEEAREMIKYMSMVSALEKQEKKAIKKNSGVGLIASNVSKLALRRRGPKYTRLQQNDTMENEKMV
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: MGSA_RHIE6
Sequence: MAGGKCLALIAHDQKKDDMAAFARANRDLLSRWKIVATGTTGGRVLDAAPDLDVTRLKSGPLGGDQQIGALISTGEVDALIFFVDPLTPMPHDVDVKALMRLAIVYDIPMALNHATAIKLLPTLEA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: Y1603_METM6
Sequence: MIKEIVKESEKGILIDIEVTTNAKKNEIGKINEWRKRIEIRIKEQPIEGKANKAIIKFLKGIFKSEISINSGTTSSQKTVLIPDKTKEDVVKILKKEIKSI
What are the official names of this protein?
UPF0235 protein MmarC6_1603.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: MRGB8_MOUSE
Sequence: MDSSFPDWNIEFREQNESYFMESSSCDMSLAMSLLSIIIAIIGLTGNVIVLQLLGFHMHRNAFSVYIFNLSGANFLFLCTHIVFSLENLIRQFHYIDIHMALFSVNVTILAYLAGVSMITAISVEYWLSVLWPTWYHAQRPKHTSTVICTLLWVFSLLLTLWNWIICKVLDYIYNWDMCWKLALIIVVWLLVLFVVLSRSNQALLFRVFCGSQQTPVTRLLVTIMLTALVVLICGFGIGICFFYWKKEENSIMPCGYFYETILLLSGVNSCANPIICLFVGSIKHCQFQCGTLRLILQRAIQESPEEEDEEVEEVVEQEGGEEDEESTTL
What is the function of this protein?
Orphan receptor.  Probably involved in the function of nociceptive neurons.  May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).
What are the official names of this protein?
Mas-related G-protein coupled receptor member B8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HM21_CAEEL
Sequence: MSQQFQASSGTGSASLREFKTEHEDLREDLPYSTLRTLFGITLDKDASQALNIALLLYGHNYPQQVVPPERNYAELDAQLESVVLEDHTAESTMEPGVSATVTEQLEEKSDKSSDGDGTSKRLTRSLKSVENETEEDHEEKEDEAPQSSRRESTRLKRKLLESQKTVQTTGNSSRASSKSQEKEVPGTKSQCAPKIRTTPEQSKAATKRQSSTTVRASSTCGSSVSSTSTVSSPDYTAKKGRATETPKLEELAPKKQSSATPKPGGEVCVWDGVQIGDLSAQMNAQIGDDEELDTVDIARRILSELKERCIPQTALAEKILARSQGTLSDLLRMPKPWSVMKNGRATFQRMSNWLGLDPDVRRALCFLPKEDVARITGLDEPTPAKRKKTVKVIRLTFTETQLKSLQKSFQQNHRPTREMRQKLSATLELDFSTVGNFFMNSRRRLRIDQQISRSSRSTGNGADTEDELDEEDVVVENVIADATDASNQPGPSHL
What is the function of this protein?
Probable DNA-binding regulatory protein involved in cell-fate specification.
What are the official names of this protein?
Homeobox protein ceh-21.
What is the protein family that this protein belongs to?
Belongs to the CUT homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSCB_SHIDS
Sequence: MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAVADTVRKLRFLDKLRSSAEQLEEKLLDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: TYSY_HALHL
Sequence: MRAYLDLVQHVLEHGHRKEDRTGTGTLSVFGHQMRFDLEAGFPLVTTKRVFWRGVAEELLWFIRGSTNARELEDKGVRIWSPWADPDGELGPVYGAQWRSWRAADGREIDQLQQVLTELRQRPDSRRHLVSAWNVGELERMNLPPCHLLFQFYVAEGRLSCQLYQRSADLFLGVPFNIASYSLLTHLVARHVGLEVGEFIWTGGDCHLYLNHLAQAREQLSRAPRPLPTLHIDPGVTDLFAVRYEHLRLAGYDPHPKLTAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF6_TRIKH
Sequence: RDCRSQSKTFVGLCVSDTNCASVCLTEHFPGGKCDGYRRCFCTKDC
What is the function of this protein?
Plant defense peptide.
What are the official names of this protein?
Defensin Tk-AMP-D6.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: DFAM3_LYMST
Sequence: PYDRISGSAFSDF
What are the official names of this protein?
Lymna-DF-amide 3.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSW_ACIAD
Sequence: MMAGFAQTTITKINQFYERWMPRLPAEMTARNVLVFCVVCLLCIGSVMVASASMPYAEYMHENPFHYVVRHAISIATAAIVAYLVYKVPLNVWFKNTFSFWLITILLLLAVLVIGTEVNGSRRWIRLAGFTLQPTEVAKVMMAIFTADYVVRRAKEVRTHWKGLVRLSGVMAITVGLIIAEPDLGATVVIVLMMVGIFFLAGAPPTQFAIMLGAVVMGIGFLILFEPYRLARAMSFTNPWADPLGTGYQLSNALMAFGRGEWFGTGLGHSVQKLSYLPEAHTDFMLAVLGEEFGFVGISIVIGLSFIMLACCIKIGHRALKHNFLRAGYLAYGISIIFLLQIIVNAGMNMGLMPTKGLTLPFISYGGTSLMMCAAMISLILRIDASTQEINPDREESNF
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: VP7_EHDV1
Sequence: MDTIAARALTVIKACNTLKEVRIVVESNVLEILGIAVNRYNGLTLRSVTMRPTSQEQRNEMFYMCLDMILAAANLNVGNISPDYIQNLATIGVLATPEIPYTMESANEIARMSGETGTWGPDRQPFGYFLAAPEVTQHGRFRQRVGQNVTTSIVSSTLAQVSMNAGARGDIQALFQNQNDPVMIYFVWRRIGTFSNAAGNAQDTPQGVTLNVGGVNMRAGVIIAYDGQAPVNVNNPGLGQGMIEIEVIYYLSLDKTMTQYPSLQAHIFNVYSYKNPLWHGLRAAILNRTTLPNNIPPIYPPHDRENVLLIILLSALADAFSVLAPDFNLFGVVPIQGPINRAVAQNAYV
What is the function of this protein?
The VP7 protein is one of the five proteins (with VP1, VP3, VP4, and VP6) which form the inner capsid of the virus.
What are the official names of this protein?
Core protein VP7.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP7 family.
What are the subcellular locations of this protein?
Virion.
Protein: SYS_STRS7
Sequence: MLDLKRIRTNFDAVAAKLKTRGVSEDTLTTLKALDEQRRALLVQTEELKAQRNIASAAIAQAKRQKKDASQQIADMQQLAANIKAIDAKLADIDQEITSIITVLPNTPHDSVPIGADEEDNVEIRRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTGARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTFELDGTSFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPETSYEELEKMTANAENILQKLELPYRVLALCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEVLRPYMGGLELIKPR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_PARDP
Sequence: METPAGKRRRDSRTVRDYIRTIVDFPHEGILFRDVTTLFADARGFRMAVDQLLAAYAGEDIDKVVGLEARGFILGGAVAHQLSVGFVPIRKKGKLPGAVISQAYALEYGKAVMEIHDDALKPGERVLIVDDLLATGGTAAAGISLCGRLGAEVVGCAFVIELPELGGRALLEGLGHEVHALTAFEGA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPH_ECO24
Sequence: MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASHKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: ACOT2_HUMAN
Sequence: MSNKLLSPHPHSVVLRSEFKMASSPAVLRASRLYQWSLKSSAQFLGSPQLRQVGQIIRVPARMAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCQTRHERYFLPPGVRREPVRVGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAMNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLHYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16940157, PubMed:10944470).  Displays higher activity toward long chain acyl CoAs (C14-C20) (PubMed:16940157, PubMed:10944470).  The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria (By similarity).
What are the official names of this protein?
Acyl-coenzyme A thioesterase 2, mitochondrial, Acyl-CoA thioesterase 2, Acyl-coenzyme A thioester hydrolase 2a, CTE-Ia, Long-chain acyl-CoA thioesterase 2, ZAP128.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SLA_ECHCS
Sequence: DQDCLSGWSFYEGHCYQLFRLKTWDEAEKYCNQWDGGHLVSIESNAKAEFVAQLISRKLPKSAIEDRVWIGLRDRSKREQCGHLWTDNSFVHYEHVVPPTKCFVLERQTEFRKWIAVNCEFKFPFVCKAKIPR
What is the function of this protein?
Echicetin itself inhibits aggregation of washed platelets induced by vWF, thrombin or alboaggregin-A (PubMed:8481512, PubMed:11290595).  However, when complexed with the pentameric plasma immunoglobulin Mkappa (IgMkappa), echicetin binds specifically to GPIb and activates platelets.  This is caused by P-selectin expression and activation of alpha-IIb/beta-3 as well as tyrosine phosphorylation of several signal transduction molecules, including p53/56(LYN), p64, p72(SYK), p70 to p90, and p120 (PubMed:11290595).  In vivo, it induces thrombocytopenia when injected into mice (PubMed:8481512), probably accounting of activation of platelets rather than inhibition (PubMed:11290595).
What are the official names of this protein?
Snaclec echicetin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYC_ENTFA
Sequence: MIKIYNTLTREKEVFTPIEARKVRMYVCGPTVYNYIHIGNARSAIAFDTIRRYFEYRGYEVNYVSNFTDVDDKIIKAAKELKITAPEVAERFIKAFEEDTQALNVQPATLHPRVMDHMPDILAFIEVLIEKGFAYEVAGDVYYRTRKFPNYGKLSHQSIDELEVGASQRTGVEQQLKEDPLDFALWKSAKEDEISWDSPWGKGRPGWHIECSVMATKHLEETIDIHGGGQDLEFPHHENEIAQSEAKTGHTFANYWMHNGYVTIGEDDEKMSKSLGNFITVHEMIQKVDPQILRFFMSTTQYRRPIRYSESTLKEAAANYQKLKNAFENLRFRQADAVASLPEDEHYLAQLNELEQRFITEMDDDFNAANGITVVYELAKMMNQYSEQATVSEPVLVAMDKLFSGWLAIFGLFFKNEELVDAQVDALIEERNQARKDRDFARSDEIRDLLKEQGIVLEDTPQGTRWRRSE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.