PharMolix/UniProtQA huggingface dataset:
Protein: TOP6B_HALMA
Sequence: MTSYQSQLGEGEGIAEELAESQRAISIAEFFEKNKHMLGFDSEARALVTAVKEAVDNALDACEEAGILPDIYVEIQESGDYYKLVVEDNGPGITKEQAPKIFGKLLYGSRFHAREQNRGQQGIGISAAVLYSQLTSGKPAKITSRPKGQDEAQYFELIVDTDTNEPEISVDETTTWERPHGTRIELEMEANMRARSTLRDYIQDTAVVNPHARVEFDEPGLDESLKFERAERAELPDETEEIRPHPHGVELGTLLKMLEATDSYSVSGFMQEEFTRVGGKTADSVIANFNDRHYGRGMAWQPPKVNEDADIERAVEDAVANKGAETTATFAAAVSDAIHDRDRVAYHEVESIVDSAAEDAEADGDTTFGATVRENAVDAAWNAVSDNLSSDLYALVDDVTTKRKDDAAVEGLASRLADKFDDDGRHRLTRDELRGYIDRAADMTEEQDDATFGETARENVLEALWTAAEGVREEPPKVSDIADDRDTASQLLSAMRETDIIAPPTDCLSPISAELVEEGLRKEFDADFYAASTRDASVHGGDPFIVEAGIAYGGELESEGTVDVMRFANRVPLVYQRGACATTDVVKSIRWRNYNLDQPGGSGIPKGPAVIMVHVASTNVPFTSESKDAIANVPEMEDEIELAIREAARELKSYLNKRRSMQQRREKQDKLATILPEMAEKLTEVTDNDELHIDDSLARIMNNVLVEREVEDDTVRVRIENNDDTNADVELTDIVTAEPQVTNGATVVEMDGEWFVKWSPTVGAGETAVLEYSVTDEAEFTVSVDGIEEEKLTVNA
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: CRCB2_HALSA
Sequence: MGIPLRIDARSTALVAVGGAVGAVLRYTVAQAIAGPLGTLAANAAGSLALGALAYEAAATDSVLSADAHTLLGTGCLSAFTTYSTFAVQTAGLAPRWMAANVATTYALGFAGVLVGRAIAATARGDRR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS2_RALPJ
Sequence: MSDTLRRLGEVLESRKLANGGDPEKSYIARLFNKGDDAILKKIGEEATETVMAAKDARAAGMTDEARSKVVYEVADLWFHTMVLLSHFDLTPDDVVGELARREGLSGLEEKALRKLQARDAAGD
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_METFK
Sequence: MFSDIEIARQAKLRKISEIAAELGLNEDSITLYGQYKAKIDLNANPQLQAQPDGKLILVTAISPSPAGEGKTTTTVGLGDALQRMGKRAVICLREPSMGPVFGMKGGAAGGGYAQVVPMEDINLHFTGDFASIALAHNLLAAMIDNHIHHGNALQIDPRQVTWKRVIDMNDRALRQVVIGLGGKVNGQPREDGFDIVVASEVMAVFCLADSLKDLRTRLGRIVVGYTYSGQPVTAQDLKAHGAMTVLLKDAIKPNLVQTLEHTPALLHGGPFANIAHGCNSVIATRTALKLGDYVVTEAGFGADLGAEKFIDIKCRKAGLHPDACVIVATIRALKYHGGADVSALSREDMLALDRGIANLEKHVENVTTHYGMPAVIALNRFDHDTEAELALVMKRMGEMGIKVVVAEHWAKGGAGAESLAAHVLQLIEGRSEGVRYVYESSETLWEKVNQVARKIYGAMDVHAPRPVRAMIDRLQDAGYGHYPICIAKTQYSFSTDASRRGVPHEHILTVRAVRLCAGAEFVVIICDDIMTMPGLPEEPCAIRMDIDDDGQVVGLY
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: FPG_CYTFI
Sequence: MPELPEVETVKRTLTELVIGKTIAGITVKWANIIKEPADVLEFETLLMNQTIRSIRRRGKFLLFEFDDIVMVSHLRMEGRYGLYEKEEPLPPHTHVIFHFTDGEELRYQDVRKFGTMHLFPKGSEEKVLPLAHLGVEPFSEQFTSELLMNAFQKTNRKIKVALLDQKTVVGLGNIYVDEALFRARIHPERLAHSLSKEEMAVLHKAIVSTLEEAVEMGGSSIKSYVNGQGEMGMFQQKLGVYGRKNEPCRQCGTDILKTVVGGRGTHFCPNCQL
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: GLGA_SYNP6
Sequence: MRILFVAAECAPFAKVGGMGDVVGSLPKVLKALGHDVRIFMPYYGFLNSKLDIPAEPIWWGYAMFNHFAVYETQLPGSDVPLYLMGHPAFDPHRIYSGEDEDWRFTFFANGAAEFSWNYWKPQVIHCHDWHTGMIPVWMHQSPDISTVFTIHNLAYQGPWRWKLEKITWCPWYMQGDSTMAAALLYADRVNTVSPTYAQQIQTPTYGEKLEGLLSFISGKLSGILNGIDVDSYNPATDTRIVANCDRDTLDKRLNNKLALQKEMGLEVNPDRFLIGFVARLVEQKGIDLLLQILDRFLSYSDAQFVVLGTGERYYETQLWELATRYPGRMSTYLMYDEGLSRRIYAGSDAFLVPSRFEPCGITQMLALRYGSVPIVRRTGGLVDTVFHHDPRHAEGNGYCFDRYEPLDLYTCLVRAWESYQYQPQWQKLQQRGMAVDLSWKQSAIAYEQLYAEAIGLPIDVLQEA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: SUCC_CHLTA
Sequence: MHLHEYQAKDLLTAYQLPIPPYHVATSVPEVETAIQAEQWKAGVVKAQVHAGGRGKNGGVVIAHSPEDLLAAADKLLHMQFSSNQTAGLSLPINKVLISPLVEIASEYYLAIVIDRKHRCPVIMLSKAGGVDIEEVAEKQPDQLLKMTLPSSGKIYGYQLRRIAKFMEWDQPIADQGNRIIRQLLQCFYEKDASLLEINPLVLTKDGSLVILDAKMTIDDNALYRHPQLADCYDPSQENIRDVLAKQLGLSYIALDGTIGCLVNGAGLAMSTLDILKLYGGSAANFLDVGGSASEKQIQEAISLVLSDKSVRVLFIHIFGGIMDCAVVASGLVSAMQGQKETIPTVIRLEGTNVDKGKDMIINAGIPCEFVTSMSEGAELAVQLSR
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: EIL5_ARATH
Sequence: MVEVQDLEPLSPIQDYDEDDLEEDVDEFERFGEEISYDDLKKRMWKDRNLMCKLKQQKRDNLNSVISSPSSSTSASSSSSSSVIVRRTEASRRKKMARSQDSVLKYMMKIMEVCKAQGFVYGIVPEKGKPVTGSSDSLRRWWKENVQFDQTAPNAVSDYLTLAAAQLISSNESLDPNSYIHMLHELQDTTLGSLLSALMQHCVPPQRRFPLEKGLAPPWWPNGTELWWGEQGAAAFEHGPPPYRKPHDLRKAWKVSVLAAVIKHMSPNLERVRRLARQSKCLQDKMMAKETDTWSRVLNQEEARLNRLKISDDEDEDRDQEQARFTCFDQEPSLNTCFIVGQDQEPLGSMRKDKRVDQEFSSNDCFLVAQDQEPRKGKKADQEWSPNSCFLVDQEPLGNKRKGEFVEKEAMLSNVYTCQNSSCPSSDVSLGFVDKNLRTGHEIECLYGTPELVNQSSGGGSDGFVRSITTSDDDYSASSKAEDTRDYHNQDGNWLDYLWFERLHDLNFSDQGFEDQTSTVDLNQLPDHSDSNQTMNEDDISLWDMGCEDKDIYMSQD
What is the function of this protein?
Putative transcription factor that may be involved in the ethylene response pathway.
What are the official names of this protein?
ETHYLENE INSENSITIVE 3-like 5 protein.
What is the protein family that this protein belongs to?
Belongs to the EIN3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CBP4B_DICDI
Sequence: MVTKKEFLEELTNATNEAIKAADKNGDNQLSKKEVNDMYKKCKYPNPTLATNSLFELFDLDKDGKLSVNEVKTAVLVDYIIEAETCLKKFVDIIFKADSNKDNKITWDEARQYFITSGSNEAQAKVLANSMFEDVDSDDDKCITREELREYAIEYFEIYPTE
What are the official names of this protein?
Calcium-binding protein 4b.
Protein: SYL_STAEQ
Sequence: MNYNHKEIEKKWQNYWEENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTQKNIQTFKRQIQELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVVDGVSERGGHPVYRKPMKQWVLKITEYADRLLEDLDELDWPESIKDMQRNWIGRSEGAKVTFKIEQSDQNIEVFTTRPDTIYGTSFLVLSPEHPLVNEITTSDKEQEVKLYQNEASKKSDLERTDLAKEKTGVFTGTFAINPLSGDKLPIWIADYVLSTYGTGAVMAVPGHDERDHEFATKFNLPIIEVIEGGEVQKYAYTGEGKHINSGELDGLENEAAISKAIELLESKGAGEKKVNYKLRDWLFSRQRYWGEPIPIIHWEDGSMTTVPEDELPLLLPETDEIKPSGTGESPLANIDAFVNVIDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPHNEKMIADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLYNQGMILGEGNEKMSKSKGNVINPDDIVASHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLIITDENSINKKIVDSNNHSLDKVYNQTVKKVTEDFDTLSFNTAISQLMVFINECYKTNEVYKPYIEGFVKMLSPIAPHIGEELWDRLGHENTITYQPWPTFDESLLVDDEVEIVVQVNGKVRAKINIPKDLSKEEMQDLALSNDNVKMSIEGKEVKKVIAVPQKLVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLB8_CHITH
Sequence: AVTPMSADQLALFKSSWNTVKHNEVDILYAVFKANPDIQAKFPQFAGKDLDSIKDSADFAVHSGRIVGFFSEVIGLIGNPENRPALKTLIDGLASSHKARGIEKAQFEEFRASLVDYLSHHLDWNDTMKSTWDLALNNMFFYILHALEVAQ
What are the official names of this protein?
Globin CTT-VIII.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: UMPS_NAEGR
Sequence: METTTIDIQALKKELVLDLIQIGALKFGRFTLKSGIVSPFYVDLRIIGPKMLRQFSVLLYHVMTVKGLTNMEKRVICGVPYSALTFSSCMSMTYDLPMVICRKERKQYGTGNMVEGIYTKNETNCILIEDVITSGASIVETAEKLENEGLLVTDALVFLTREQLPLTNGMHILKKGEKVYNVHPCLTMTEVTQVLLDEGKMSQEQREDILQFIGTNTFSETKTTAVPQKKKELTFTERAELTNNEFSKKLFKLMEEKQTNLCVAADITSKDDLLKLADETGPEICMLKTHIDTLDDQPDEQFTQQLKELAKKHNFLIFEDRKLADIGQVVKQQYARGPFKIAQWSDLCNSHLVSGGSATVKALKESLKEENITEPRGLLLIAQMSTEGATTGESTKQEALKVALENPDFVSGFICQSKLRDDLDQFLYCTPGVRLDVKGDSLGQQYNSPEYVVCEKKCDVIIVGRGIYHDKERQNAAKLYRKLGWEAYQKRIQQ
What is the function of this protein?
Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP).
What are the official names of this protein?
Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the OMP decarboxylase family.
Protein: SURE_VIBVY
Sequence: MEDKQAKPLRILLSNDDGVFAEGIRTLASELRTLAEVIIVAPDRNRSGASNSLTLEQPLRVTCVEENVYSVQGTPTDCVHFALNELLKNDLPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQSIAFSLVGKTHFKTAATIAKRIVEQHLAKPIPTNRLLNINIPDLPLEQLEEIRVTRLGARHHAENMIKQLDPRGHEIYWLGPPGKEQDAGEGTDFHTIEQGYVSITPLQVDLTAHESLRAMDTWLKEK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCE5_LEPPU
Sequence: MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKDAGRQLVAHAMGKIAEKV
What is the function of this protein?
Has antibacterial activity against Gram-negative bacterium E. coli ATCC 25922 (MIC=300 uM) but not against S. pneumoniae ATCC 700603, S. choleraesuis ATCC 14028 or Gram-positive bacterium S. aureus ATCC 29313.  Shows very little hemolytic activity and no cytotoxicity.
What are the official names of this protein?
Ocellatin-PT5.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ocellatin subfamily.
Protein: CIS3_YEAST
Sequence: MQFKNVALAASVAALSATASAEGYTPGEPWSTLTPTGSISCGAAEYTTTFGIAVQAITSSKAKRDVISQIGDGQVQATSAATAQATDSQAQATTTATPTSSEKISSSASKTSTNATSSSCATPSLKDSSCKNSGTLELTLKDGVLTDAKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITEDGYLALGDSDVFYQCLSGNFYNLYDQNVAEQCSAIHLEAVSLVDC
What is the function of this protein?
Component of the outer cell wall layer.  Required for stability of the cell wall and for optimal growth.  Required for resistance against several antifungal and cell wall-perturbing agents.
What are the official names of this protein?
Cell wall mannoprotein CIS3, Covalently-linked cell wall protein 5/11, Protein with internal repeats 4, Soluble cell wall protein 8.
What is the protein family that this protein belongs to?
Belongs to the PIR protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Covalently attached to the cell wall. Localizes predominantly on the surface of growing buds.
Protein: GLYC5_ARATH
Sequence: MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND
What is the function of this protein?
Catalyzes the interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase 5, AtSHMT5, Glycine hydroxymethyltransferase 5, Protein EMBRYO SAC DEVELOPMENT ARREST 36, Protein EMBRYO SAC DEVELOPMENT ARREST 37, Serine methylase 5.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFEB_HELPO
Sequence: TSKISTTYEEEGRQSKIQPRAFVITRSGPTSRSSSYSARQSYGSRSSITPGVYQQLSSSGITDFRGTREKEKREMQNLNERLAGYIEKVHFLDAQVKKLEAENEALRNRKSESLQPIRDAYENELAQARKVIDELSSTKGVSEAKVAGLQDEIASLRELIGTYENQSKDYRKKIESLGNQIGEYEGELHTLRIRCGSLEDENAKVRELLDKIQDQNRRLRADLDTETSAHIEADCLAQTKTEECEFYKDLLDQLELLKPEPMQIKGMDYAEFWKSELSKCVRDIQSAYDEKIDIIQQDIEAKYSSQINSLRSGNVKDGMQLQHVQEEVKKLRTQAGEKNAAYAELAAKFASLQAERDAIGRQCSELERELEELRIKYNQDIGDLSNELSAVLAQLQTLTDVKITMELEIACYRKLLEGEESRVGLRSLVEQAIGVQGRGTASLKDTIQQS
What is the function of this protein?
Epithelial intermediate filament protein.
What are the official names of this protein?
Non-neuronal cytoplasmic intermediate filament protein B, IFB.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO8A1_RABIT
Sequence: MAVPPGPPQLLQVLLTISLGSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLTMGKEMPHAQYGKEYPHLPQYMKEVQPVPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGQGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGDRGPKGPPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGPPGEPGPQGPIGVPGVQGPPGLPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPVGAPGMGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGIRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGITGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPAPQGEYLPDMGLGIDGVKTPHAYAAKKGKNGGPAYEMPAFTAELTAPFPPVGAPIKFDRLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM
What is the function of this protein?
Vastatin, the C-terminal fragment comprising the NC1 domain, inhibits aortic endothelial cell proliferation and causes cell apoptosis.
What are the official names of this protein?
Collagen alpha-1(VIII) chain, Endothelial collagen.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: NDHI_JASNU
Sequence: MFPMVTEFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYNRHELNYNQIALGRLPVSIIDDYTIRTISSSPQIKNG
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: XRN2_CAEEL
Sequence: MGVPAFFRWLTKKYPATVVNANEDRQRDQDGNRVPVDCTQPNPNFQEFDNLYLDMNGIIHPCTHPEDRPAPKNEDEMFALIFEYIDRIYSIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEMAEKEASIEEQRNRLMAEGIAVPPKKKEEAHFDSNCITPGTPFMARLADALRYYIHDRVTNDASWANIEIILSDANVPGEGEHKIMDYVRKQRGNPAHDPNTVHCLCGADADLIMLGIATHEANFNIIREEFVPNQPRACDLCGQYGHELKECRGAENETDLGDDYCKPEQREKNFIFLRIPVLREYLEKELSMPNLPFKFDVERALDDWVFLCFFVGNDFLPHLPSLEIREGAIDRLIKLYKEMVYQMKGYLTKDGIPELDRVEMIMKGLGRVEDEIFKRRQQDEERFQENQRNKKARMQMYGGGGRGGRGRGRGRGQQPAFVPTHGILAPMAAPMHHSGESTRQMASEARQTAMKFTNDANETAAANLKALLNVKGEESPADIASRKRKAEQPLIKPEEEEDEGPKDDIRLYESGWKDRYYRAKFDVGSDDIEFRHRVAWAYVEGLCWVLRYYYQGCASWDWYFPYHYAPFASDFETVGEFQPDFTRPTKPFNPLEQLMSVFPAASKQHLPVEWQKLMIQDDSPIIDLYPADFRIDLNGKKYAWQGVALLPFVDETRLLATLQSVYPTLTAEEKQRNTRGPNRIFIGRNHKSFEFFQQVAESKSDDLVPLDPTLLNGVSGKIAYDSTATAPGLPFVSPVNHDECQDLPTNCGICVLYEDPEYPQDYIFPALRLDGAKEPEKTLKPDDWNDRRDGRYQPQVGFNRNAPRGSLDQSGHRQVHHYVRGGGGGGGGYRGNSYDDRRGGGGGGGGYNDRQDFGRNYGGRDGGGPQRYHDQQQQRQGGYQGGGYGGGYGGGGGGGGGGGGGSYHQPYNQDQRRGGRGGGGGPPGYQRPPYRGGGGGGYHGNSSWR
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity (PubMed:19734881, PubMed:21397849).  Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA (PubMed:19734881, PubMed:21397849, PubMed:26779609).  Degradation role is enhanced when in complex with paxt-1 (PubMed:24462208, PubMed:26779609).  Partially redundant to xrn-1 in miRNA guide strand degradation (PubMed:19734881, PubMed:21397849).  Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA (PubMed:19734881, PubMed:21397849).  Positively regulates molting of the pharyngeal cuticle (PubMed:16122351, PubMed:19734881).
What are the official names of this protein?
5'-3' exoribonuclease 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBEY_SALSV
Sequence: MSQVILDLQLACENHAGLPDEAQFQRWLDGVIPQFQEEAEVTIRLVDEAESHDLNLTYRGKDKPTNVLSFPFEAPPGIEMPLLGDLIICRQVVEQEAQEQSKPLEAHWAHMVVHGSLHLLGYDHIDDDEAEEMESLETEIMLAMGYEDPYIAEKIAE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_RHIL3
Sequence: MSESRTSADGGMETSYGFREVPDGQKQGLVNQVFHKVAKRYDIMNDVMSMGMHRAWKDAMISALNPRKEPGYKVLDVAGGTGDIAFRIVEASGRQAHATVLDINGSMLGVGAERAEKKKLSGNLTFVEANAEELPFEAGSFDAYTIAFGIRNVPRIDAALSEAYRVLKRGGRLLVLEFSEVDMPLLDKIYDAWSFNAIPQFGKAITGDAEPYQYLVESIRKFPNQENFAAMIRQAGFSRVTFTNYTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SUCA_PIG
Sequence: MTAALVAAPAAATMASGSSGLAAARLLSRSFLLQQNGIRHCSYTASRKHLYVDKNTKVICQGFTGKQGTFHSQQALEYGTNLVGGTTPGKGGKTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAAAAINEAIDAEVPLVVCITEGIPQQDMVRVKHRLLRQGKTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFTDCLEIFLNDPATEGIILIGEIGGNAEENAAEFLKQHNSGPKSKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKITALQSAGVVVSMSPAQLGTTIYKEFEKRKML
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
What are the official names of this protein?
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RECO_GEOSW
Sequence: MFEKCEAIVIRAIDYGETNKIVTFFTREWGKVATMARGAKKPSSRLSAVTQPFTHGYYLIQRSRGVGVLHQGDIIDSMRTIREDIFTAAYASYIVEMTDKVTEEQQRNPYLFELLLQTLQYMNEGLDLEILACIYEMKMLSVMGIPPKLDHCAVCGRTEGKFSFSIKEAGFLCHRCEKTDPYRIPLSAASVRLLRLFYYIDLSRLGTISVKEETKKELRAVLSSYYDEYSGLSLKTKRFLMQIDELKKIGYPYQNQTENGSGG
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SCPA_STRA3
Sequence: MDIKLKDFEGPLDLLLHLVSKYEVDIYDVPIVEVIEQYLAYIATLQAMRLEVAGEYMLMASQLMLIKSRNLLPKVVESTPIEDDPEMELLSQLEEYRRFKVLSEELANQHQERAKYFSKPKQEVIFEDAILLHDKSVMDLFLTFSQMMSQKQKELSNSQTVIEKEDYRIEDMMIVIERHFNLKKKTTLQEVFADCQTKSEMITLFLAMLELIKLHQITVEQDSNFSQVILRKEEK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: RL30_ALKOO
Sequence: MAKVSIKLTKSVIGTKPNQRKTVEALGLKKIGQVTEKEMTPQLRGMIDVVQHLVEVKEI
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: UNG_SCHPO
Sequence: MTVLNTTDKRKADDTVNKLDGKLKQPRLDNFFKTNTSSPALKDTQVLDNKENNSVSKFNKEKWAENLTPAQRKLLQLEIDTLESSWFDALKDEFLKPYFLNLKEFLMKEWQSQRVFPPKEDIYSWSHHTPLHKTKVILLGQDPYHNIGQAHGLCFSVRPGIPCPPSLVNIYKAIKIDYPDFVIPKTGYLVPWADQGILMLNASLTVRAHQAASHSGKGWETFTSAVLQVALNRNRKGLVILAWGTPAAKRLQGLPLKAHYVLRSVHPSPLSAHRGFFECHHFKKTNEWLEEQYGPEKCINWSAVSEQKAKIKSSELESSSTE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.