PharMolix/UniProtQA huggingface dataset:
Protein: RL29_ACIB5
Sequence: MKTKDLREKSVEELKALLDEQQLNQFRLRMAKATGQLGKSHEVQVARKTIARIKTLLTEKQGNGQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RUFY2_HUMAN
Sequence: MATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP
What are the official names of this protein?
RUN and FYVE domain-containing protein 2, Rab4-interacting protein related.
What are the subcellular locations of this protein?
Nucleus.
Protein: GC_GAHVB
Sequence: MLTPRVLRALGWTGLFFLLLSPSNVLGASLSRDLETPPFLSFDPSNISINGAPLTEVPHAPSTESVSTNSESTNEHTITETTGKNAYIHNNASTDKQNANDTHKMPNILCDTEEVFVFLNETGRFVCTLKVDPPSDSEWSNFVLDLIFNPIEYHANEKNVEAARIAGLYGVPGSDYAYPRQSELISSIRRDPQGTFWTSPSPHGNKYFIWINKTTNTMGVEIRNVDYADNGYMQVIMRDHFNRPLIDKHIYIRVCQRPASVDVLAPPVLSGENYKASCIVRHFYPPGSVYVSWRQNGNIATPRKDRDGSFWWFESGRGATLVSTITLGNSGIDFPPKISCLVAWKQGDMISTTNATAIPTVYHHPRLSLAFKDGYAICTIECVPSEITVRWLVHDEAQPNTTYNTVVTGLCRTIDRHRNLLSRIPVWDNWTKTKYTCRLIGYPFDEDKFQDSEYYDATPSARGTPMVITVTAVLGLAVILGMGIIMTALCLYNSTRKNIRL
What is the function of this protein?
May play an immunoevasive role in the pathogenesis of Marek's disease.  It is a candidate for causing the early-stage immunosuppression that occurs after MDHV infection.
What are the official names of this protein?
Envelope glycoprotein C homolog, A antigen, Glycoprotein A, GA, Secretory glycoprotein GP57-65.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein C family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Single-pass membrane protein. Note=Predominantly secreted. Secreted, but a small amount of mature GP57-65 is anchored in the plasma membrane or held by other interactions.
Protein: PUR7_BACAN
Sequence: MQKLELLYEGKAKRIYRTESADMVWVEYKDSATAFNGEKKETITGKGRLNNEITTLLFRKLQEVGIKTHFVEKLSETEQLVKKVSIIPLEVVTRNVIAGSLSKRLGMEEGTVLAEPIVEFYFKDDDLGDPLVTEDHIRVLNVASPEQVSVLRDMALQINQVLIDHFASCRVRLVDFKLEFGVTDEGAIILADEISPDTCRLWDETSNEKFDKDVFRRDLGNLTDAYEEILKRLGGISHV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: FOLD_PECCP
Sequence: MAAKIIDGKTIAQQVKDEVAARVTQRLAAGKRAPGLAVVLVGENPASQIYVSSKRKVCEEVGFISRSYDLPATTTESELLTLIDQLNADQAIDGILVQLPLPEGIDNTKVIERIAPSKDVDGFHPYNVGRLCQRAPLLRACTPRGIVTLLERYNIDTFGLNAVVVGASNIVGRPMSLELLLAGCTTTVTHRFTKNLRHHIENADLLVVAVGKPGFIPGEWIKPGAIVLDVGINRLESGKVVGDVEFETAQERASYISPVPGGVGPMTVATLIQNTLQACEEYHDHAE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: VL3_BPV4
Sequence: MIFLQESLVAHISYQPLDEDPCPPQYILEAPVDLWYPVISRFIIGPFGYKGHKAVIMACAGTMSFLLQLLIVLEALTLVYQYTLLTQRLNHKKLIQPLSLSTTSDMWKNGICL
What are the official names of this protein?
Probable protein L3.
Protein: LPXC_ERWT9
Sequence: MIKQRTLKRIVQTTGVGLHTGKKVTLTLRPASANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVVEVNAPEIPIMDGSAAPFIYLLMDAGIEELNSAKKFVRIKQPVRVEDGDKWAELSPHNGFSLDFTIDFNHPAIDASTQRYRMDFSAEAFARQISRARTFGFMRDIEALQSRGLALGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLYMCGNNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEWATFEDEATLPVTFRAPNLVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RL18_SALEP
Sequence: MDKKSARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: XKR6_HUMAN
Sequence: MAAKSDGGGVGVGFAQLHNLDEAVGSGGEEDGEPGGGGCGGGGDGSEPGESSSMHICHCCNTSSCYWGCRSACLRSLLGRKPRRSAAADGGDQPLQPPAAPGAGRQPPTPSAARPEPPPPQVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYVYFGLTLFFVLVPSLLVQSLSFRWFVQDYTGGGLGAVEGLTSRGPPMMGAGYVHGAARGGPGVRVSPTPGAQRLCRLSVWIWQSVIHLLQMGQVWRYIRTMYLGIQSQRRKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLYIMLQKNSAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGAIIQVFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRDPETTDSYAVPALCCVFISFVAGIAMMLLYYGVLHPTGPRAKILASSCCAELLWGIPLPPDVEPMAPEIPGYRGTQVTPTRAVTEQQEDLTADTCLPVFQVRPMGPPTPLGRPYLPEGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL
What are the official names of this protein?
XK-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TOC75_ORYSJ
Sequence: MALTSQSLFFSPLAAGPSRRVRGRGRSTSVSAAASASSHNSQPHGHPQQPLAVASSSSKSESKGSKTFALASAITAAASGAFLLASSGGGFGGGAGGPLGGGGGGWGAGGGGGGGGGGGGGGFWSRIFSGGAAHADEKSSGDWDPHGLPANINVPMTKLSGLKRYKISELKFFDRAAGGGGAFTGPEDSFFEMVTLQPGGVYTKSQLLKELETLVSCGMFERVDLEGKAKPDGTLGLTVSFVESVWSAAKQFKCINVGLMSQSGQVDFDQDMTEREKMDYLRKQERDYQQRVRGAKPCILPDNVRGEVLGMMKKQEKVSARLLQRIRDHVQKWYHNEGFVCAQVVNFGNLNTSEVVCEVVEGDITKVEYQFQDKLGNFVEGNTQIPIIDRELPQQLRPGHIFNIGAGKQALKNINSLALFSNIEVNPRPDETKEGGIVVEIKLKELEPKSAEVSTEWSIVPGREGRPTLASIQPGGTVSFEHRNIYGLNRSIVGSVTSSNLLNPQDDLSFKLEYVHPYLDGVDDRNKNRTFKTSCFNTRKLSPVFVAGPNMDEAPPVWVDRVGFKANITESFTRQSKFTYGLVVEEITTRDETNSICTHGSRAMPSGGLSMDGPPTTLSGTGIDRMAFLQANITRDNTEFVNGAVIGDRCIFQLDQGLGIGSKNPFFNRHQLTLTKFVNLNKQEKGAGKPLPAVLVLHGHYAGCVGDLPSYDAFTLGGPYSVRGYGMGELGASRNVLEVASELRIPVRNTYVYGFVEHGTDLGSSKDVKGNPTEFFRRVGHGSSYGLGVKLGLVRGEYIVDHNAGTGTVFFRFGERF
What is the function of this protein?
Mediates the insertion of proteins targeted to the outer membrane of chloroplasts.  Required for the import of protein precursors into chloroplasts.  Forms the voltage-dependent preprotein translocation channels (hydrophilic beta barrel) of the TOC complex in the chloroplastic outer membrane (By similarity).
What are the official names of this protein?
Protein TOC75, chloroplastic, 75 kDa translocon at the outer-envelope-membrane of chloroplasts.
What is the protein family that this protein belongs to?
Belongs to the TOC75 family.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Multi-pass membrane protein.
Protein: AGRB_LISMH
Sequence: MSNFTAKVPLSERMADVLISKDRWKDDEEGYLKVKYGLEIILINVMKFALVYGIALVTGLLLQTVTVHLSYLWLRRYSFGLHATKTLNCTLISLMMFVLAPFVFQNVPSNNWIVLGTFAFILLNMFLFAPADTESLPLIGEEHRKTLKRKAMIGTLILTGIALLIPFAEMKTLIMIGSLFQVISINPLTYKLLRRRYRNYEKYE
What is the function of this protein?
May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.
What are the official names of this protein?
Putative AgrB-like protein.
What is the protein family that this protein belongs to?
Belongs to the AgrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLIN5_RAT
Sequence: MDQRGKDTTLALHSRMSGDQTAQDPGSSLGELDQHNVVKRVVALPLVRATCTAVSGAYNSAKDRHPLLGSACRFAEHCVCSVATCALDHAQPLLEHLQPKLATVNDLACRGLDKLEEKLPFLQQPSDTVVTSAKDAVAKSVTGVVDLAQRGRRWSGELRRSVSQAMDTVLRRSVSQAMDTVLGKSEELVDHFLPMTEAELVALATESQGPEVGSVEEQRQKQGYFVRLGSLSARLRHLAYQHSLGKLRESKHRTQEMLAQLQKTLELIQHMQSRASPTPTFHHPKVQELCGDWSPCLENGYRHSQVELETLALSRSLTLELQSAVDALAGCVRGLPPSAQAKVAEVQRSVDALQATFADAHCLGDVAPTALAEGQDSVAQAHACVDEFLDLVLRAMPLAWLVGPFAPILVERSEPLINLATCVDEVVGDPDPRWAHMDWPAQQRAWEAEPADPGGQEAEPPLGQVKHTMMPELDF
What is the function of this protein?
Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues.  Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation.  In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE.  Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets.  Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2.  Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.
What are the official names of this protein?
Perilipin-5, Lipid storage droplet protein 5.
What is the protein family that this protein belongs to?
Belongs to the perilipin family.
What are the subcellular locations of this protein?
Lipid droplet. Cytoplasm. Mitochondrion. Note=Lipid droplet surface-associated. Exchanges between lipid droplets and the cytoplasm.
Protein: ACLU_ASPOR
Sequence: MNDYIRVNCTELRWPELVCAEPGSNSRGHSPPFHIANASITQLKAIDLLFLIDFSISKIMESLLQLETALRAVVEETKRPNAAAAFASLRRADPNNDPALTAVASRVVDLASEVTQLLEPAYLALADHLFGYQHTQCLAAVVELRIPDYLASGPQTFEQLSISSGTRRDRLRQVLRLLYNNGVFSYDAESDSVRNNEASEMLKQDHWTQWHRWASVCSKQFYQMAQGLPRAMSAGVTRSPAQVHYDTDESMFSYLERNGTMVQLRECMGAAAIAQTPGMITGYPWAELSNHTLFDLGGGDGSLIAGLLRAIPTLQGGIMDTPRVLPFLQEAFHHPSSKYADVALRIPPERVIAGDFLQEVIPSEAYVMRWCLHDWNDEQACQILRNIRRSIINSPVSRLIVLESVLADGRWGRMSRLGDINVMVTAEHGQERTETQWRQLAACTGWKVVSITQLPGAWPSAIDMRPVERPENV
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).  The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411).  One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411).  After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411).  In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411).  Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
What are the official names of this protein?
O-methyltransferase aclU, Aspirochlorine biosynthesis protein U.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: MURA_NITWN
Sequence: MDRIRIVGGNRLNGTIPISGAKNAALPLMIAALLTEETLILDNVPRLADVAQLQRILGNHGVDIMSAGKRPGDHEYQGQTLHISAASVIDTTAPYELVSKMRASFWVIAPLLARMHEARVSLPGGCAIGTRPVDLLILALEKLGARIAIDGGYVIASAPAGLRGAEVAFPKVTVSGTHVALMAATLASGTTVITNAACEPEIVDVADCLNKMGARVSGAGTPRIVIEGVGRLGGARHTVLPDRIETGTYAMAVAMTGGEVLLRGARPELLQAALDVLTEAGAEITPNNEGIRVARNGAGINPVTVSTAPFPGFPTDLQAQLMALMTRARGTSHITETIFENRFMHVQELARLGARIHLDGETATIEGIETLRGAPVMATDLRASVSLVIAGLAGEGETMVNRVYHLDRGFEQLEKKLSACGASIERIRA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHH_XENLA
Sequence: MLVATQSLLLLSFICTLVTPPGLACGPGRGIGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSDCFKELTPNYNPDIMFKDEESTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHLEESLHYEGRAVDITTSDRDRSKYGMLGRLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGCFPAGARVMVEFGGTKAVKDLRPGDRVLSSDPQGNLLYSDFLMFIDQERDVKKLFYVIETSQRKIRLTAAHLLFVAQTKVNGTRSFKSVFASNIQPGDLIYTADPKTMTLKAVKVEKVDLEEDTGAYAPLTAHGTVVIDQVLASCYAVIEEHTWAHLAFAPLRFGMSLSSYIYPRDSSPPSGLQPHHQVDLQSHHQVDLQSHHQVDLQSHHQLEGIHWYSQLLYQIGTWLLDSNSLHPLGMATKSS
What is the function of this protein?
The dually lipidated sonic hedgehog protein N-product (ShhNp) is a morphogen which is essential for a variety of patterning events during development.  Induces ventral cell fate in the neural tube and somites (By similarity).  Involved in the patterning of the anterior-posterior axis of the developing limb bud (By similarity).  Essential for axon guidance (By similarity).  Binds to the patched (PTCH1) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes (By similarity).  In the absence of SHH, PTCH1 represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, ShhNC, VHH-1, X-SHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
[Sonic hedgehog protein]: Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane. SUBCELLULAR LOCATION: [Sonic hedgehog protein N-product]: Cell membrane; Lipid-anchor. Note=The dual-lipidated sonic hedgehog protein N-product (ShhNp) is firmly tethered to the cell membrane where it forms multimers (By similarity). Further solubilization and release from the cell surface seem to be achieved through different mechanisms, including the interaction with DISP1 and SCUBE2, movement by lipoprotein particles, transport by cellular extensions called cytonemes or by the proteolytic removal of both terminal lipidated peptides.
Protein: RS17E_ARCFU
Sequence: MGTVKPAYIKVIARELLKKYPEVFTGNFDENKRLVAELTNIQSKTVRNRVAGYITRRVNRGLVNV
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: SYP_METRJ
Sequence: MRLSRYFMPTLRETPKEAEIVSHRLMLRAGLVRQEAAGIYAWLPLGLRVLERVCAVIRREQDRSGAVEILMPTVQSAELWRESGRYDAYGKEMLRLKDRHDREMLYGPTAEEMVTEIFRASVRSYKDLPKNLYQISWKFRDEVRPRFGTMRSREFLMKDAYSFDFDQAGARHAYNRMFVAYLRTFAGLGLKAIPMRADTGPIGGDLSHEFIILAKTGESEVFCDKAYLGFDIPPATVDFDDVAALQGIVDAWTSHYAATEEMHEPAAFAEVPEDSRMAARGIEVGHIFYFGTKYSEPMGAKVAGPDGIERPVHMGSYGIGPSRLVAAIIEASHDEAGIIWPDAVAPFDVALINLKVGDSATEAACAQIQSDLEAAGLSVLYDDRDERPGAKFATADLIGLPWQVIVGPKGLAEGKVELKRRAGGERESLATVDLLARIRRV
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRN_MOUSE
Sequence: MWVLMSWLAFAAGLVAGTQCPDGQFCPVACCLDQGGANYSCCNPLLDTWPRITSHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDPVPRPLL
What is the function of this protein?
Stabilizes CTSD through interaction with CTSD leading to maintain its aspartic-type peptidase activity.
What are the official names of this protein?
Progranulin, PGRN, Acrogranin, Epithelin/granulin precursor, Glycoprotein of 88 Kda, GP88, Glycoprotein 88, PC cell-derived growth factor, PCDGF, Proepithelin, PEPI.
What is the protein family that this protein belongs to?
Belongs to the granulin family.
What are the subcellular locations of this protein?
Secreted. Lysosome. Note=Endocytosed by SORT1 and delivred to lysosomes. Targeted to lysosome by PSAP via M6PR and LRP1, in both biosynthetic and endocytic pathways (By similarity). Co-localized with GBA in the intracellular trafficking compartments until to lysosome (PubMed:27789271).
Protein: RSMH_ACICJ
Sequence: MSGGLSHVPVLREEAVAMLAPRADGVYLDGTFGGGGYSASMLEAASCTVWAIDRDPAAIARGAALAARYPDRLHLIEGRFGDLLALLRDRGVTALDGAVFDFGVSSYQLDDPSRGFSFRTDGPLDMRMGAAGPTAADIVNGYAEAELADILFHFGEERASRRIAAAIVRRRAAQPFETTADLAAVIRTVVRPDRSGIDPATRSFQALRIEVNQELAEIERALEAAASLLAPGGRLVAVSFHSLEDRIVKRFMNAATGHVAAPSRHDPSGLARQAAAPRFRALTRGVVTPGEAETVANPRARSARLRGIERLAA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_RIPO1
Sequence: MRHQCRVPLLGKPADQRKALLRSLTTELIRHGQIMTTKTRAKAVRSEVERMITLAKDGSLAARRRALGYMYDKQLVHSLFADVQSRYGNRNGGYTRITRTLRRRGDNAEMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: KTHY_TREPA
Sequence: MNILHNFVVFEGIDGTGTSTQLRALERHFQARKDMVFTQEPTGGEIGTLIRDVLQKRVIMSSKALGLLFAADRHEHLEGAGGINDCLAEGKIVLCDRYVFSSLVYQGMAVSGSFAYELNKEFPLPEVVFYFDAPIEVCVERITARGLQTELYEYTSFQEKARKGYETIFRKCRHLYPAMKVIEIDAREEIEVVHERILHHLREYRRLK
What are the official names of this protein?
Putative thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ALM1_EMIHU
Sequence: MGNCTSHPHHEPQVHFDTVDGMATVKAFAGIRQVTMGVLRIDYEYQTNLGDILDPRSFDFRIISATAEGLTFAKAKAGDKLDATGKELLERAVRQLIDNGADFIVGDCGFLVYWQVMVRDYAQDYAQKKYGRKCPVMMSSLVLALPLLATIPSGGQIGILTASEKSLQAVQKKLPIVIEDQQKEDGGQRSRSVPAAEDPSGIMINFSDPRFKVVGLDEVKDFKHALDAQGADAVNDRRDIAVQIAAYCQKVQEKNPQIAAWLIECTEAGGFAWAIKVGTGLPVWDPITLGRFLSLGFTANVPNVALTLGQHGENPLDPSATTAGKGRCTGEEPGQIHALGAEFQAIREGTL
What is the function of this protein?
Mediates cleavage of dimethylsulfonioproprionate (DMSP) into dimethyl sulfide (DMS) and acrylate.  DMS is the principal form by which sulfur is transported from oceans to the atmosphere and is a key component of the ocean sulfur cycle.
What are the official names of this protein?
Dimethylsulfonioproprionate lyase 1, DMSP lyase 1, Dimethylpropiothetin dethiomethylase 1.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family. ALMA1 subfamily.
Protein: RK5_TRICV
Sequence: MRNQHSLEEIAEIHSLLEDIKGEYEKGIRAVIKKNNPELFGNPHTIPKLQKIQINRGLGLAAQNTNILKKSINEFTAITGQKPIITRAKKAIAGFKIRENMELGLTVTLRGSKMYSFLTKLIFFTFAQIRDFRGLSVRSFDKAGNYTLGLKEQLIFPEIDYDDVDQTQGFSITLVFSSTAPKSRSKTMDRVLNGMVLFKFLRFPLNDSGYYDKYSSFSEVSQAWDRKKHLRRKRWSQE
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y004_MYCBT
Sequence: MTGSVDRPDQNRGERSMKSPGLDLVRRTLDEARAAARARGQDAGRGRVASVASGRVAGRRRSWSGPGPDIRDPQPLGKAARELAKKRGWSVRVAEGMVLGQWSAVVGHQIAEHARPTALNDGVLSVIAESTAWATQLRIMQAQLLAKIAAAVGNDVVRSLKITGPAAPSWRKGPRHIAGRGPRDTYG
What are the official names of this protein?
UPF0232 protein JTY_0004.
What is the protein family that this protein belongs to?
Belongs to the UPF0232 family.
Protein: AZUR1_ALCXX
Sequence: AECSVDIAGNDGMQFDKKEITVSKSCKQFTVNLKHPGKLAKNVMGHNWVLTKQADMQGAVNDGMAAGLDNNYVKKDDARVIAHTKVIGGGETDSVTFDVSKLAAGEDYAYFCSFPGHFALMKGVLKLVD
What is the function of this protein?
Transfers electrons from cytochrome c551 to cytochrome oxidase.
What are the official names of this protein?
Azurin-1, AZN-1, Azurin-I.
What are the subcellular locations of this protein?
Periplasm.
Protein: AROL_SHISS
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURR_ECOBW
Sequence: MLYLTKISNAGSEFTENEQKIADFLQANVSELQSVSSRQMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALLDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLTDSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQRSSELTQRLK
What is the function of this protein?
Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc).  Binds to two adjacent inverted repeats within the operator region.  MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator.
What are the official names of this protein?
HTH-type transcriptional regulator MurR, MurPQ operon repressor.
Protein: RS16_ECOL5
Sequence: MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RRF_MYCPU
Sequence: MDISIINEVFSTLEEKSMNVVSNFEFNLSKISTGRANPQLIKNIKVSYYEELIPLEQISNISVPEPQQLLIKPFDHNITKEIHKSLLLANLDVAIVNEGNQIRLNFPALNTQRRKELVKSLNKFTEQARVSIRLLRQESNKKIKSFKSEISEDDIKKYETKIQTINDSYIEQIDEITKRKERELMEI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.