PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_MANSM
Sequence: MKDLVKFLKAQSKTSEDFDVIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYIVIEPGMTDLEKGQLLTEEQFMDAEDRWADEFDAKMGAEAIQALLRDMDLEHECETLREELQETNSETKRKKITKRLKLLEAFMQSGNKPEWMVMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFRPFIYAKLESRGFASTIKAAKKMVEREDAIVWDILAEVIREHPILLNRAPTLHRLGIQAFEPILIEGKAMQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLEARALMMSTNNVLSPANGDPIIVPSQDVVLGIYYMTREKVNAKGEGMLLQDPREAEKAYRTGRAELHSRVKIRITEYVKNAEGEFEPQTTLTDTTIGRAILWMIAPKGMPYSLFNQTLGKKAISKLINECYRRLGVKASVMFADQIMYTGFAYAARSGSSVGIDDMVIPEKKYEIISAAEAEVAEIQEQFQSGLVTAGERYNKVIDIWATANERVAKAMMENLSTEEVVNREGNLEKQSSFNSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVIVEDDCGTHEGIVMTPLIEGGDEKVSLRELVLGRVAAEDILKPGTEEVLFPRNTLLDEKVCDILDENSVDSVKVRSVVTCDTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSVQVKNSGSIRLTNVKSVTNNEGKLVVTSRNTELTIIDAFGRTKEHYKVPYGAVLNKGDGEAVTAGETVANWDPHTMPVVSEVAGFVKFVDIVDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPAIKVVDAQGNDIFIPGVDVLAQYFLPGKAIVTLDDGAEVQVGEPLARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEITGIVSFGKETKGKRRLVITPVEGEAYEEMIPKWRQLNVFEGEMVERGDVISDGAETPHDILRLRGVHAVTEYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKGIITKAYDSEFLEGEQVEVARVKIVNRKREAEGKPPVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQNRIKNRGQANVVEEQEVKFSAADEAEIEAEFNMIAEDPAASLAEMLNMADDAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ATPA_ENTFA
Sequence: MAIKAEEISALIKEQIENYQQQLAVEEVGTVTYVGDGIARAHGLENAMSGELVEFSNGSYGMAQNLETNDVGIIILGDFETIREGDKVQRTGKIMEVPVGEALIGRVVNPLGQPLDGLGEIKTDKTRPVEATAPGVMQRQSVAEPMQTGLKAIDALVPIGRGQRELVIGDRKTGKTSIAIDTIINQKGQDVICIYVAIGQKESTVRNQVETLRKFGALDYTIVVTAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPFVETQAGDISAYIPTNVISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLPVEKQVLILYALTHGFLDSVSVDKILHFEQDLFDYFDGKHADLLETIRTTKDLPDTDALDAAITEFSEMFAAANNSGDSAKEALEKIDNA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HOT1_CANGA
Sequence: MSDAGDSKLAKEQSDASTGTCNGNGTGNGTGSGTATANATTTPTPTPTSIPTAAGSVTDVTATSSMVLAKLDDISSRLTMLESNFNNVFSKINDQNSMILDLKQNNSHAFLRLSSKVNKLETHVAALASNNPQSAFVTDLLNSITNVSSSYLRKMKHNGAENLNVQLSTHENGFVHPTPNDSPNMMGPIYYNQIETSKARGQLKSLNRKKTFTLNPNGIKKRRLGHHHGNSGSRSNNLNVTFDITGQVGQPGYDTSLNSATPNNHAMTPSNVISSSNSYSELQSLNGLQSNTTASDGRTLSPVNTVQALKTPYLTATNQHSLNHGSLNNYNLNFPQFLDNTNSVTLSRLGSSSPVEKRDGIVMSHSAPQLDNGSITYPDNRLHIRNQASQDILGGASQGQPQKINNIDEDGYQEDDEEEESELNKHKNKVGNLKYNTTLTDSHSINDDRKPTVNVYASTGHPVNNTKSEYLEDDESNDSDNSHETDEESEDEVEEYDEEDDMVNEEDRQPYSRKPKEPASERKRKKLRKINKYRNNVIEPRKKDDKEKDAQNSDLNYMLLKAPSSVKTIWEEYVNGIDGNPSIRGLEEKYGNKWRIKRNKKTFSRRKRLYKFILNGIDKGKTADEMIDMLEKQRLYRDENGEIKRRTIGWLQQSLIGI
What is the function of this protein?
Required for a complete transcriptional response to osmotic stress.
What are the official names of this protein?
High-osmolarity-induced transcription protein 1.
What is the protein family that this protein belongs to?
Belongs to the HOT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBFA_HAEI8
Sequence: MAREFKRSDRVAQEIQKEIAVILQREVKDPRIGMVTVSDVEVSSDLSYAKIFVTFLFDHDETAIEQGMKGLEKASPYIRSLLGKAMRLRIVPEIRFIYDQSLVEGMRMSNLVTNVVREDEKKHVEESN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTD_SALDC
Sequence: MTLWINGDWITGQGERRRKTNPVSAEIIWQGNDANAAQVAEACQAARAAFPRWARQPFAARQAIVEKFAALLEAHKAELTEVIARETGKPRWEAATEVTAMINKIAISIKAYHARTGEQKSELVDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTLIFKPSELTPWTGETVIKLWERAGLPAGVLNLVQGGRETGQALSSLDDLDGLLFTGSASTGYQLHRQLSGQPEKILALEMGGNNPLIIEDVANIDAAVHLTLQSAFITAGQRCTCARRLLVKQGAQGDAFLARLVDVAGRLQPGRWDDDPQPFIGGLISAQAAQHVMEAWRQREALGGRTLLAPRKVKEGTSLLTPGIIELTGVADVPDEEVFGPLLNVWRYAHFDEAIRLANNTRFGLSCGLVSTDRAQFEQLLLEARAGIVNWNKPLTGAASTAPFGGVGASGNHRPSAWYAADYCAWPMVSLESPELTLPATLSPGLDFSRREAV
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: LSPA_DEHMB
Sequence: MTRGLVFFVSTACGILADQLSKFIITANLATGTSIPESGFFQIVHVHNTGAAFSIFQGHIEWLIAASVLGVILAMTAFFIRKKLPFLDTRPGLIALGVILAGTVGNLIDRVRLGYVTDFIRVGDFPTFNIADSCLTVGVIGLLLLYIVSSHVSGDTSENV
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OTNC_PECAS
Sequence: MSEHHNGTEASLSSEQRARAEMVKLGASFFQRGYATGSAGNLSLLLDDGTLLATPTGSCLGELDAERLSKVSLSGEWISGDKPSKEVSFHLSIYRNDPECKAIVHLHSTYLTALSCLEGLDTQDAIKPFTPYVVMRVGKVPVVPYYRPGDARLGEDLAKLASRYKAFLLANHGPVVTGKNLRAAADNMEELEETAKLIFILGDRKIRYLTADDIAELS
What is the function of this protein?
Catalyzes the decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate (DHAP) and CO(2).
What are the official names of this protein?
3-oxo-tetronate 4-phosphate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: HCP_SHESA
Sequence: MFCIQCEQTIRTPAGNGCSYAQGMCGKLAATSDLQDLLIYMLQGVSVYATKARELGVINPEVDTFVPKAFFSTLTNVNFDDERIIAYAKQAAEYRESLKNAYEAACEAAGKRAESLPPVAQFVLGTSKPEMLSQAPVALLNKDKNEIHEDILGLRLLCLYGLKGAAAYMEHARVLGKTDAEIAGRFHEIMAFLGEPSVDADKLFTTAMDIGQLNYRIMAMLDAGETEAFGHPEPTVVNTKPVKGKAILVSGHDMKDLELILEQTAGKGINVYTHGEMLPALAYPAFKKYAHLVGNYGSAWQNQQKEFANFPGAVVMTSNCIIDPNVGQYSDRIFTRSIVGWPGVTHVIGDDFSVVIDKALSLDGFQYDEIPHNITIGFARNALMAAAPTVVENVKNGSIKHFFLVGGCDGDKSERSYFTDLAKSAPKDSVILTLGCGKYKFNKLEFGDINGIPRLLDIGQCNDAYSAIQLAIALSQIFECDINELPLNLVLSWFEQKAIVVLLTLLSLGVKNIRTGPTPPAFLTANLAKILEEKFGLRNTTTVEADLKTMLNVA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6B_YEAST
Sequence: MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEIRKRRASSLKA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  eS6 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (PubMed:15590835).
What are the official names of this protein?
40S ribosomal protein S6-B, RP9, S10, Small ribosomal subunit protein eS6-B, YS4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: IOLG_ACICJ
Sequence: MTLRIGVIGTGAIGRDHMRRINQTLSGAKVTAVSDVNIESVRTARADLAPEAEVVGSGEEVAASAGVDAVVVTSWGATHEQYVLAAIAAGKPVFCEKPLSTTAAGAGRIVEAETAFGRRLVQVGFMRRYDAGYRMLKAVVENEIGRPLMVHAAHRNPSVPEQYITPMAIQDTLIHEIDVLRWLLDDDYVSAQVISPRRTRHAHARVEDPQIVLLETKSGIRIDVEIFVNCRYGYDIQCQVVGEEGLASLPDPMAVVMRKDAKLQSAIMTDWKDRFIDSYDLELQDFIKAAARGTASGPTAWDGYVAAVSSDACVEAQSRPGSIVPISLPARPPLYN
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: PK1L3_MOUSE
Sequence: MLLQRRSWLWLYIRIGVILGDILGRKPSIREQHGGNSCYQLNRLFCDFQEADNYCHAQRGRLAHTWNPKLRGFLKSFLNEETVWWVRGNLTLPGSHPGINQTGGDDVLRNQKPGECPSVVTHSNAVFSRWNLCIEKHHFICQAAAFPPQGASIWRNEFGPGPLLPMKRRGAETERHMIPGNGPPLAMCHQPAPPELFETLCFPIDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQEDSPLGVISTHPQMSFQSSTSQALDETAGERVPTIPDFQAHSEFQKACAILQRLRDFLPTSPTSAQKNNSWSSQTPAVSCPFQPLGRLTTTEKSSHQMAQQDMEQHPMDGAHNAFGISAGGSEIQSDIQLRSEFEVEDMLETSLMALGEIHRAFCQQSLCPQSAVTLASPSATLMLSSQNVSTLPLSTYTLGEPAPLTLGFPSAEALKELLNKHPGVNLQVTGLAFNPFKTLDDKNIVGSIGNVQLSSAYQSIRVHDLIEDIEIMLWRNASMETQPTSLNTSTDHFTISVNITSLEKTLIVTIEPESPLLMTLHLGFQDQLAHTHFYLNISLPRDQVWQKDEEYTWVLTPENLWYGTGTYYIMAVENKSTEAAQHTPVLVSVVTAVTQCYFWDRYNRTWKSDGCQVGPKSTILKTQCLCDHLTFFSSDFFIVPRTVDVENTIKLLLHVTNNPVGVSLLSSLLGFYILLAMWASRKDREDMQKVKVTVLADNDPSSASHYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWYVSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPASRSELSSFRHLFSSTIVEKFTQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVINIMFWKMGGTTAKRGTEQLGPLAVTLSELLVSIQTSIILFPIHLIFGRLFQLIHPPEALPQLPFIQAAWPPALVCESPSLTQVVKELKETVGFLLRRNTQLLSECEPSSCSSCDINKLAKLLSGLIYCHLEDEGCHQQTESHWEDAVSENHYHFCRYLLQLLRRLKAHLEALGATQDHQSCDFSEAVSQLQNLQELLETQTLRRGPGPCRHSTSFPILSPGEGKKPMSFCLFRWLKCSCWLLLGVISLASAFFITLYSLELDKDQATSWVISMMLSVLQDIFISQPIKVIFLTLLFSLMANHMPWLNKDKEQHARRIVALWAKCPWSAPGLRDKNNPIYTAPAMNNLAKPTRKAWKKQLSKLTGGTLVQILFLTLLMTTVYSAKDSSRFFLHRAIWKRFSHRFSEIKTVEDFYPWANGTLLPNLYGDYRGFITDGNSFLLGNVLIRQTRIPNDIFFPGSLHKQMKSPPQHQEDRENYGAGWVPPDTNITKVDSIWHYQNQESLGGYPIQGELATYSGGGYVVRLGRNHSAATRVLQHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILESSGVGTFLTSLQLDSLTSLQSSERGFAWIVSQVVYYLLVCYYAFIQGCRLKRQRLAFFTRKRNLLDTSIVLISFSILGLSMQSLSLLHKKMQQYHCDRDRFISFYEALRVNSAVTHLRGFLLLFATVRVWDLLRHHAQLQVINKTLSKAWDEVLGFILIIVVLLSSYAMTFNLLFGWSISDYQSFFRSIVTVVGLLMGTSKHKEVIALYPILGSLLVLSSIILMGLVIINLFVSAILIAFGKERKACEKEATLTDMLLQKLSSLLGIRLHQNPSEEHADNTGSSNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKVL
What is the function of this protein?
Component of a calcium channel.  May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.
What are the official names of this protein?
Polycystic kidney disease protein 1-like 3, PC1-like 3 protein, Polycystin-1L3.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Interaction with PKD2L1 is required for localization to the cell membrane.
Protein: HIS7_METPP
Sequence: MTEPNRVAEVRRDTAETKIRVRVDLDGTGVARLATGIGFFDHMLDQLARHGLVDLEIEADGDLHIDGHHTVEDVGITLGQAFAKAVGDKKGLRRYGHAYVPLDEALSRVVVDFSGRPGLHMRVPFKAGMIGALDTQLVYEFFQGFVNHAGVTLHIDNLHGDNAHHQCETVFKAFARALRMALERDPRMAGVIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK14_BARVE
Sequence: MIQPQTYLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAIPNTPLERSEVIRAVIVRTCKELKRNNGTIIRYDDNAAVVIDQEGNPKGTRVFGAIPRELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPM_LOCMI
Sequence: MDAIKKKMQAMKLEKDNALDRALLCEQQARDANLRAEKAEEEARALQKKIQTIENDLDQTQESLGQVMAKLEEKEKALQNAESEVAALNRRIQLLEEDLERSEERLATATAKLAEASQAADESERARKILENRSLADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEAGESKIVELEEELRVVGNNLKSLEVSEEKANQREEEISNRLRTLTTRLKEAEARAEFAERSVQKLQKEVDRLEDELVIEKEKYKIIGDDLDSAFVELIL
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: EFTU_LEPIC
Sequence: MAKEKFDRSKPHLNVGTIGHVDHGKTTLTAAITTTLAKAIGGKNKAVAYDQIDNAPEEKARGITIATSHQEYETANRHYAHVDCPGHADYVKNMITGAAQMDAAILVVSATDGPMPQTKEHILLARQVGVPYVIVFINKADMLAADERAEMIEMVEMDVRELLNKYSFPGDTTPIVHGSAVKALEGDESEIGMPAILKLMEALDTFVPNPKRVIDKPFLMPVEDVFSITGRGTVATGRVEQGVLKVNDEVEIIGIRPTTKTVVTGIEMFRKLLDQAEAGDNIGALLRGTKKEEIERGQVLAKPGSITPHKKFAAEVYVLTKDEGGRHTPFINNYRPQFYFRTTDVTGVCNLPNGVEMVMPGDNVSLTVELISPIAMDKGLKFAIREGGRTIGSGVVAEITE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTRF1_STAAN
Sequence: MNKTKGFTKYKKMRYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSDNIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYVIDSIGSLSFIVLILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWNKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
What are the official names of this protein?
Putative O-acetyltransferase SA0834.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FUTA_CAEEL
Sequence: MTARSIKLFFARWKYLMFACCITYLLVIYAPISKSEQKDWKEGEIELSNDHELDVPILQKEELKPQQRPSFEENVPKKKTFNFNPVGKEPFDVEEVLTSSDIKLEERMTATVIPGQKRLILSWNAGHSQDNLQGCPDWNCEFTQVRARAPDADAVLIAHMDNDFVPKPNQYVVYFSQESPANSGIQIPRPDYINMTLGFRHDTPAGSPYGYTVKLGAKSRKTGQVVDANLVNGKAKGAAWFVSHCQTNSKREDFVKKLQKHLQIDIYGGCGPMKCARGDSKCDTMLDTDYHFYVTFENSICEDYVTEKLWKSGYQNTIIPLVLKRKLVEPFVPPNSFIAIDDFKSVKEMGDYLNYLMNNKTAYMEYFEWRHDYKVVFLDGSHHDVLERPWGFCQVCRMAWTEPRQKVLIPNWDAYWRQTCEKDGTLVDSIPLD
What is the function of this protein?
Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue (with or without alpha 1,6-linked fucose), next to the peptide chains in N-glycans (PubMed:15364955, PubMed:9675224, PubMed:17369288, PubMed:21515584).  Unlike in mammals, does not require the prior action of N-acetylglucosaminyltransferase I to generate complex N-glycans (PubMed:15364955).
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase fut-1, Fucosyltransferase fut-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: PA2H1_BOTMO
Sequence: MRTLWIMAVLLVGVEGSLVELGKMILQETGKNPVTSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTDCNPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYKNNYLKPFCKKADPC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity (PubMed:28265084).  In vivo, it displays local myotoxin and edema-inducing activities and is lethal by intraperitoneal injection (PubMed:10620318, PubMed:33865953).  The myotoxicity effect is weaker in comparison to other myotoxins, probably due to the formation of high molecular weight complexes and to the oligomeric conformation (conventional dimer) (PubMed:10620318, PubMed:23573271).  It shows specificity toward neurons and myotubes, but not on a variety of other cell types (PubMed:28265084, PubMed:10620318).  This PLA2 excites a cohort of sensory neurons via ATP release and consequent activation of P2RX2 and/or P2RX3 purinergic receptors (PubMed:28265084).  Pannexin hemichannels act as downstream mediators of toxin-evoked ATP release (PubMed:28265084).  In vivo, it elicits nonneurogenic inflammatory pain, thermal hyperalgesia, and mechanical allodynia, of which the latter is completely dependent on purinergic signaling (PubMed:28265084).
What are the official names of this protein?
Basic phospholipase A2 homolog MjTX-I, Basic phospholipase A2 homolog 1, svPLA2 homolog, Basic phospholipase A2 homolog BomoTx, Myotoxin I.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TATA_HERAR
Sequence: MGSFSIWHWLIVLVIVALVFGTKKIGSMGTDVGKAVKGFKDGMKGEDDKPAAQNAAPSQVADKGTVDVEVKEKSNS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SSRP_MYCBT
Sequence: MSKSSRGGRQIVASNRKARHNYSIIEVFEAGVALQGTEVKSLREGQASLADSFATIDDGEVWLRNAHIPEYRHGSWTNHEPRRNRKLLLHRRQIDTLVGKIREGNFALVPLSLYFAEGKVKVELALARGKQARDKRQDMARRDAQREVLRELGRRAKGMT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GFA_XANC8
Sequence: MANVSIHPAVDGGVVHGSTEGFAGGTLQCLCASNKVTVDVASQSAHNHACGCSKCWKPEGAKFSVVAVAPRDKVTVTAHPEKLKIVDESATIQRHACTGCGVHLYGRIENKDHAFYGLDFIHTELSQQSGWSPPGFAAFVSSIIETGTPPDQMDGVRARLTELGLTPYDCLSPALMDALSTNVARHKGLLH
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: AROF_STRRM
Sequence: TRRFDDVLDEVKGFFEVH
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-II DAHP synthase family.
Protein: Y004_TREPA
Sequence: MNNGVNKLSDLLVLTTEYIQASYETEAFDAHREWVCIVGNPVALHSTLVDIRNGKVVVKVTHPGWAQYLLLKKDEIVHALRRRYPSLGVTGMSTYVDSTSRTPSAKKDMQGLSVSEKQTRPVPELAEVFEQLRTLFQVKTEEPSH
What are the official names of this protein?
Uncharacterized protein TP_0004.
Protein: ASTD_COLP3
Sequence: MSHANPVQFINGQWQAGLGHDVSSSNPARNEVIWQGKTASKDQVNDAVLSARQAFESWANISLEARVAVVTKFAELLAENKDALATTIALETGKPKWETTGEAGAMVAKVAISLKAYNERTGTVENPMPGAKAFIRHKPHGVVAIFGPYNFPGHLPNGHIVPALIAGNTIVFKPSELTPRVAQEMLKLWEQAGLPNGVINLVQGEVETGKALASHKLIDGLFFTGSSNTGHILHEQFAGQPGKILALEMGGNNPLVVKDVSDIDAVVHDIVQSAFVTTGQRCTCARRLFIEANEQGDAILARLIEVTKNLTIGYYDDEAQPFMGSMISEKAALSLVDAQAKLLALGAKSVLDLKHLEVGTGFVSPGIIDVSDIIADIPDEEYFGPLVKLYRYNDFDKAIDEANNTGFGLSAGLLSDSEASYNHFFTRIRAGIVNWNKPITGASSAAPFGGIGASGNHRASAFYAADYCAYPIASVEAEKVSLPETLTPGMKF
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: YFH7_SCHPO
Sequence: MIESELATSRWSLMLEADIATQTTRSLTNELSFIVAGLRPSTKESVLHFLELIFINLKYQSKKWLYSLVICKSLIALLGRKRLSANVRKIVRFLNVIICVIGLWKGLSAMSGKNTFINGLQSYLISETALPELGSFQELSTSSLGSFRMFQQIAVGFVDALFCTRIPASLWIKYKEYTTSAETTVPQECGLCMMCVQRGDERVAITTPYTTDCGHTYCYACIMSRLKLVNNVSCPICKHRIRFALPDQTMG
What are the official names of this protein?
Uncharacterized RING finger protein C23A1.07.
What are the subcellular locations of this protein?
Cytoplasm.