PharMolix/UniProtQA huggingface dataset:
Protein: CLPB_COREF
Sequence: MSSFNPTTKTSEAMQAALQQASANGNPDIRPAHLLVAILDQADGVAAPVLTAAGVDPKTILAEAQKLVDGYPKASGSNLANPNFNRDALNALTASQELAGELGDEYVSTEVLLAGIARGKSDAADLLKGKGATYDAIKAAFQSVRGSQKVTSQDPEGQFQALEKYSTDLTKLAREGKIDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLKGKTLISLDLGSMVAGAKYRGEFEERLKAVLDEIKGANGEIVTFIDELHTIVGAGASGESAMDAGNMIKPLLARGELRLVGATTLNEYRKYIEKDTALERRFQQVYVGEPSVEDTVGILRGLKERYEVHHGVRIQDSALVAAAELSHRYITSRFLPDKAIDLVDEAASRLRMEIDSSPQEIDELERIVRRLEIEEVALTKETDVASRERLERLRSELADEREKLSELKARWQNEKAVIDDVRKFKEELEALRSESDIAEREGDYGRVAELRYGRIPELEKKIAEAEEKIGGADNSMLTEEVTPEVIAEVVSAWTGIPAGKMMQGETEKLLNMERFLGKRVVGQHEAVTAVSDAVRRSRAGVADPNRPTGSFLFLGPTGVGKTELAKAVSEFLFDDERAMVRIDMSEYSEKHSVARLVGAPPGYVGYDQGGQLTEAVRRRPYTTVLFDEVEKAHPDVFDILLQVLDDGRLTDGQGRTVDFRNTILILTSNLGAGGTREQMMDAVKMAFKPEFINRLDDIVVFDPLSQEQLASIVEIQISQLAERLSDRRLTLRVSDAAKLWLAERGYDPAYGARPLRRLIQQAIGDQLAKELLAGEIRDGDRVLVDVADGGQYLAVSREH
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRT_SALG2
Sequence: MKTPRLPIAIQQAVMRRLRENLAQANLKLDRHYPEPKLVYTQRGTSAGTAWLESYEIRLNPVLLLENIDTFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWMMESVLGVPARRTHQFALQSVRRNTFPYHCQCQQHQLTVRRHNRVVRGEAVYRCVHCGEPLVAG
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_METKA
Sequence: MEVIKVGGEVLDRVEDLARVIDDSILVHGGGPEVSDVMERMGLEPRFVRGLRVTDRETLQVVMMVLAGLVNKRLVAELRSEGINALGLSGVDGGLLIAEKRSEVVDGEEVDLGYVGDVKRVNAELLESLLDAGYVPVVAPLGAGEDGTVYNVNADTAAGAIAGAVRADRLVLLTDVPGVLEDLDDPETLIERVRPEDVEELEEKGIVTGGMVPKLEAAKMAVEAGCREAVITNLEGLLEGRGTIVR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_TRIEI
Sequence: MRKIYQRVLLKLSGEALMGSLGYGIDPAVVQGIAQEVAEVAATGIQIAIVVGGGNIFRGVKAASKGMDRATADYVGMIATVMNAITLQDALEQVGVPTRVQTAIAMQELAEPYIRRRAIRHLEKGRVVVFGAGSGNPFFTTDTTAALRAAEIEAEVIFKATKVDGVYDSDPHKNQEAKRYESLSYGEVLTLDLRVMDSTAIALCKENNIPIIVFNLSVSGNICKAVMGEKIGTIVGGFHESKRS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_SHESH
Sequence: MRPSDRTPAQSRPVTITRQFTAHAEGSVLVEFGDTKVLCTASFEEGVPRFLKGKGQGWVTAEYGMLPRSTHSRMNREAARGKQSGRTQEIQRLIGRSLRAAVDMKALGENTIVIDCDVIQADGGTRTAAITGACVALVDSLNWARGKGILKTNPLKFLIAAVSVGIYKGEPICDLEYIEDSEAETDMNVVMTETGKMIEIQGTAEGEPFSHEELLSLLELAKHGIREIVDIQKAALS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: YBEY_BACCN
Sequence: MSLVIDFFDETEEVKEEYVNMIRELLEKAAQMEGVEDGTELSVTFVDNERIREINRDYRGKDQPTDVISFALEDMGEGEVEIIGADMPRMLGDLIISIPRTKEQAEEYGHSFDRELGFLALHGFLHLLGYDHMTEEDEKEMFGKQKEILGAFGLRR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTBP2_BOVIN
Sequence: MRPPTTARCPGRVLQNPWRSFWPLTLALFVGMGQAQRDPVGRYEPAGRDASRLRRPGGSPVVATAKVYSLFREQDAPVRGSPPAELVQPSWGSPRRSTEAEARRPPRAQQPRRVQPPAQTWRSRPSGQQQSAPRARAAPALPRLETVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGPPSLRRSSVARESTTARVRPPAPQLQRARTLSGLSQTRSSQQHVGLSQTTRLYPAPAASGQLTSNALPMGPGPERRDGAPQAAYLDRPSSSWGLNLTEKIKKIKIVFTPTICKQTCARGRCANSCERGDTTTLYSQSGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDQEPPERGPRHRAPLEGPLKQSTFTLPLSNQLASVNPSLVNVHIRHPPEASVQIHQVARVRGEAEEAPEENSVETRPSPRLPAGPGPGRWDSNRIPARSGEAPRLPPPVVPRTPALLGRCYLSTLNGQCANPLPELTAHEDCCGSVGAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCEDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSLCEKCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSRDRGPKRNGTLPRPAERQPLRAATGTWVEAETIPDKGDSQASQVTTSVTQLSTWVPGGALGTPTPSVPEQGIPEAREEAQVTAPTNVLVTPAPSGIDRCAAGATNICGPGTCVNLPDGYRCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYKLATSGATQECQDIDECEQPGVCSRGRCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGKCVNSPGSYTCLPCEEGYRGQGGSCVDVNECLTPGVCTHGTCINLEGSFRCSCEQGYEVTPDEKGCKDVDECAIRASCPTGLCLNTEGSFTCSACESGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCRDCEAGYQPSALGHTCEDVDECEDPQSSCLGGECKNTAGSYQCLCPPGFQLANGTVCEDVDECVGEEYCAPRGECLNSHGSFFCLCADGFVSADGGTSCQDVDECAVTDRCVGGQCVNTDGSFNCVCETGFQPSPESGECVDIDECEDLGEPICGAWRCENSPGSYRCVLGCQPGFHMAPTGDCIDIDECANDTVCGSHGFCDNTDGAFRCLCDQGFETSPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGRCRPRGAGGPSVPEARPGAHPPGPVRMECYSGQKDQTPCSSLLGRNTTQAECCCTQGTGWGDACDLCPDEDSVEFSEICPSGKGYIPVEGAWMFGQTTYTDADECVMFGPGLCRNGRCLNTVPGYICLCNPGYHYNAASRKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGVEDLPDHDIHMDICWKRVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGIHFRPGYEYSPGPDDLHYSLYGPDGVPFYNYLGPEDAIPEPLFPSTAGRPGDRIPLPEPPLQPSELQPHYVASHPGLCCCKNGEEVGSEAVSLPSSPSAHHCQQEHQAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDTAHMACVDVNECDDLNGPAALCVHGHCDNTEGSYRCHCLPGYVAEAGPPHCTAKE
What is the function of this protein?
May play an integral structural role in elastic-fiber architectural organization and/or assembly.
What are the official names of this protein?
Latent-transforming growth factor beta-binding protein 2, LTBP-2.
What is the protein family that this protein belongs to?
Belongs to the LTBP family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: SLD2_ARATH
Sequence: MADQTKKRYVTSEDLKKHNKPGDLWISIQGKVYDVSDWVKSHPGGEAAILNLAGQDVTDAFIAYHPGTAWHHLEKLHNGYHVRDHHVSDVSRDYRRLAAEFSKRGLFDKKGHVTLYTLTCVGVMLAAVLYGVLACTSIWAHLISAVLLGLLWIQSAYVGHDSGHYTVTSTKPCNKLIQLLSGNCLTGISIAWWKWTHNAHHIACNSLDHDPDLQHIPIFAVSTKFFNSMTSRFYGRKLTFDPLARFLISYQHWTFYPVMCVGRINLFIQTFLLLFSKRHVPDRALNIAGILVFWTWFPLLVSFLPNWQERFIFVFVSFAVTAIQHVQFCLNHFAADVYTGPPNGNDWFEKQTAGTLDISCRSFMDWFFGGLQFQLEHHLFPRLPRCHLRTVSPVVKELCKKHNLPYRSLSWWEANVWTIRTLKNAAIQARDATNPVLKNLLWEAVNTHG
What is the function of this protein?
Plays a major role as delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides with or without a hydroxy group at the 4-position.  The enzyme produces both the 8E and 8Z isomers (in a 4:1 ratio).  This structural modification contributes to the quantitative partitioning of ceramides between the two major sphingolipid classes, glucosylceramides and glycosylinositolphosphoryl ceramides.  Sphingolipids are important membrane components involved in environmental stress responses, such as resistance to chilling, and act as cell signaling molecules.
What are the official names of this protein?
Delta(8)-fatty-acid desaturase 2, Delta(8)-sphingolipid desaturase 2, Sphingoid long-chain base desaturase 2, Sphingoid LCB desaturase 2, Sphingolipid 8-(E/Z)-desaturase 2.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AROB_HYDCU
Sequence: MKTLTVELGERSYPIFIGQGLLGQAELFKPYVTGTQVLIVSNTTVAPLYLEKAKQAFSGYDVKTVILPDGEQYKNLDVLNQIFDVAIENRFDRKCTFVALGGGVIGDMTGFAAASYQRGVNFIQIPTTLLSQVDSSVGGKTGVNHPKGKNMIGAFHQPECVVIDTDTLNTLEDRELSAGLAEVIKYGLIVDYPFFEWLEQNLPGLLARDPVVLAEAIERSCQNKATIVAKDEKEAGLRALFNLGHTFGHAIEAGMGYGNWLHGEGVSAGMMQAVYLSKLMGDLTQTDQKRIAAILQSAHLPVMPPKEMSVQQFLDLMAGDKKVQAGQIRLVLLKAIGQAYVTGDYPAELLERTLIEYR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GB_HHV23
Sequence: MRGGGLICALVVGALVAAVASAAPAAPAAPRASGGVAATVAANGGPASRPPPVPSPATTKARKRKTKKPPKRPEATPPPDANATVAAGHATLRAHLREIKVENADAQFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRYSQFMGIFEDRAPVPFEEVIDKINAKGVCRSTAKYVRNNMETTAFHRDDHETDMELKPAKVATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTSYAADRFKQVDGFYARDLTTKARATSPTTRNLLTTPKFTVAWDWVPKRPAVCTMTKWQEVDEMLRAEYGGSFRFSSDAISTTFTTNLTQYSLSRVDLGDCIGRDAREAIDRMFARKYNATHIKVGQPQYYLATGGFLIAYQPLLSNTLAELYVREYMREQDRKPRNATPAPLREAPSANASVERIKTTSSIEFARLQFTYNHIQRHVNDMLGRIAVAWCELQNHELTLWNEARKLNPNAIASATVGRRVSARMLGDVMAVSTCVPVAPDNVIVQNSMRVSSRPGTCYSRPLVSFRYEDQGPLIEGQLGENNELRLTRDALEPCTVGHRRYFIFGGGYVYFEEYAYSHQLSRADVTTVSTFIDLNITMLEDHEFVPLEVYTRHEIKDSGLLDYTEVQRRNQLHDLRFADIDTVIRADANAAMFAGLCAFFEGMGDLGRAVGKVVMGVVGGVVSAVSGVSSFMSNPFGALAVGLLVLAGLVAAFFAFRYVLQLQRNPMKALYPLTTKELKTSDPGGVGGEGEEGAEGGGFDEAKLAEAREMIRYMALVSAMERTEHKARKKGTSALLSSKVTNMVLRKRNKARYSPLHNEDEAGDEDEL
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: USP11_PINMG
Sequence: MSCGTYKRGSLTFLLVVALAVPVFCQSRTRLKWKTRISTTPEVMVEERALVRNETNNRYVKIYSTRHPKKTAISNATSTIDFEKRKVAIKVRTYVNSQRTEACYLMDPINTHDMTMTVNVIKSRNQTQVIDKTAVMDMVVNSNKLTIDDLKKDYELSRIYKECDKAVVESGLYTIIKGTPSASATSTDPPIDVLGLIPQSGIHSQHIRIHFNTNPQTAPV
What are the official names of this protein?
Uncharacterized shell protein 11, Nacre uncharacterized shell protein 18.
What are the subcellular locations of this protein?
Secreted.
Protein: DM43_DIDMR
Sequence: LKAMDPTPPLWIKTESPSTPWTNVTLLCVATNTEELSFQVWKDGELLSTLPVVGLVGKFWLGPVTADNRGIYRCRILTSENDWTPLSAPVEVTGKEPLPAPSLHAEPGPWILPGLETKLHCRGMLLGMIFDLYQEGEQEPVKSSQTPSAEATFIVNSTGNYSCLYRAPASAPSVNSTPSETIHVVIPDFLPKANFYILNDRDFRPGDIVTFSCWARFSEREYDLEFKLFKDGQETPVEVVPISDPMKVFFDLTAVGPKDGGKYSCRYRFRNGPPIWSEDSNVLELDLSTGQ
What is the function of this protein?
Metalloproteinase inhibitor.
What are the official names of this protein?
Venom metalloproteinase inhibitor DM43.
Protein: O10A3_HUMAN
Sequence: MKRQNQSCVVEFILLGFSNFPELQVQLFGVFLVIYVVTLMGNAIITVIISLNQSLHVPMYLFLLNLSVVEVSFSAVITPEMLVVLSTEKTMISFVGCFAQMYFILLFGGTECFLLGAMAYDRFAAICHPLNYPVIMNRGVFMKLVIFSWISGIMVATVQTTWVFSFPFCGPNEINHLFCETPPVLELVCADTFLFEIYAFTGTILIVMVPFLLILLSYIRVLFAILKMPSTTGRQKAFSTCASHLTSVTLFYGTANMTYLQPKSGYSPETKKLISLAYTLLTPLLNPLIYSLRNSEMKRTLIKLWRRKVILHTF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 10A3, HTPCRX12, Olfactory receptor OR11-97.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACCD_LOTJA
Sequence: MEKWWLNSMLRNRELAYKCGLSKSTDRFGPIENTSVSEDPPILTDMDKNIHSWNDIENCSYNNVDYLVGVENIRNFLSNKSFLVRDSKRNSYSIYFAIENQILEIDNDHLFLSELESFFSRYTNSIYLNNSSKGDGDHYMYDTESSWNNNINSFIENYIRSQICIDNYILGDGDKYNDSYFYSYICSTIRKKSSERERTSIITSTNNLNDSDFTKIEGSNDLDETQKYKHLWIECENCYGLNYKKILKSKMNICEHCGYHLKMSSSDRIELSIDPGTWNPMDEDMISVDPIEFHSEEEPYKDRIDSYQKTTGLTEAVQTGTGHLNGIPVAIGIMDFEFMGGSMGSVVGEKITRLVEYATNQLLPLIVVCASGGARMQEGSLSLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKAVPEGSQAAEYLFHKGLFDSIVPRNPLKGILSELFQLHAFFPLIQNEKESRS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y955_MYCTU
Sequence: MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSDMTGAWGAIASMWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATGVWSRVGRRALAATALPDWLHDSMRAAAAGVLALLGLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGALVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDADESSPPVDMFDGAASEQPPASVAEDVPPSHDDIANGLKAPTADDEALPLSDEPPPRAD
What are the official names of this protein?
Uncharacterized protein Rv0955.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREE_DEIRA
Sequence: MTRLTGLRRPLLPIAGAKQAPEQAIDGPQVEVPLTAVDRRRVRRRLHAPDGAELQLAFPTGTVLSPGTVLGTRGGVSYVVSAAPEDVAVVVPRTLAEAAHTAHAVGNLHRDFVEDAGAFLTPWDAPIELLLTRLGVPFTRETRPFHGRPSWEHEG
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNJB2_MOUSE
Sequence: MASYYEILDVPRSASPDDIKKAYRKKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDRYGREGLTGAGSGPSRSETGGAGPGFTFTFRSPEEVFREFFGSGDPFSELFDDLGVFSELQNQGPRLTGPFFTFSSSFPANSDFSSSSFSFSPGAGAFRSVSTSTTFVQGRRITTRRIMENGQERVEVEEDGQLKSVSINGVPDDLALGLELSRREQQPSVAPGLGVMQVRPTSLSRPPDHDLSEDEDLQLAMAYSLSEMEAAGQKPAGGRGAQQRQHGQPKAQHRDLDVGGTHKSVRGEAAKLSPSSEEKASRCHIL
What is the function of this protein?
Functions as a co-chaperone, regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family.  In parallel, also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins.  Thereby, may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT, MC4R, PRKN, RHO and SOD1 and be crucial for many biological processes.  Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein degradation of misfolded proteins.
What are the official names of this protein?
DnaJ homolog subfamily B member 2, DnaJ homolog subfamily B member 10, mDj8.
What are the subcellular locations of this protein?
[Isoform 2]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side.
Protein: EX7S_KLEP3
Sequence: MPKKNEAPASFETALGELEQIVNRLESGDLPLEEALSEFERGVQLARQGQSQLQKAEQRVQILLADSEDSPTTPFTPDAE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_BRUO2
Sequence: MTEQVQANETETPVAVADERIIRETGIDAKVAGIVEPVINTLGFRLVRVRLSGLNGQTLQIMAERPDGTMTVDDCELVSRTVAPVLDVEDPISGKYHLEISSPGIDRPLVRKSDFSDWAGHIAKVETSIVHEGRKKFRGRIVVGEADSVTIESDQISYGNEPVVRIPFDLISDARLVLTDDLIRDALRKDKALREGRIPGDDLGAEPEDAASTETQEKK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXH2_TOBAC
Sequence: MAEEGQVIGVHTVDAWNEHLQKGIDDKKLIVVDFTASWCGPCKFIASFYAELAKKMPTVTFLKVDVDELKSVATDWAVEAMPTFMFLKEGKIVDKVVGAKKDELQQTIAKHISSTSTA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The H form is known to activate a number of cytosolic enzymes (By similarity).
What are the official names of this protein?
Thioredoxin H-type 2, Trx-H2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant H-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_MYCPA
Sequence: MKVNPSVKPICDKCRVIRRHGRVMVICSDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PCCA_RAT
Sequence: MAGLWVRTVALLAARRHWRRSSQQLLWTLKRAPRSSQQLLWTLKRAPVYSQQCLVVSRSLSSVEYEPKEKTFDKILIANRGEIACRVIKTCRKMGIRTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTGAQAVHPGYGFLSENKEFAKCLAAEDVTFIGPDTHAIQAMGDKIESKLLAKRAKVNTIPGFDGVLKDADEAVRIAREIGYPVMIKASAGGGGKGMRIPWDDEETRDGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDPETRRAMGEQAVAWPKAVKYSSAGTVEFLVDSQKNFYFLEMNTRLQVEHPVTECITGLDLVQEMILVAKGYPLRHKQEDIPISGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVRVDSGIQPGSDISIYHDPMISKLVTYGSDRAEALKRMEDALDSYVIRGVTHNIPLLREVIINTRFVKGDISTKFLSDVYPDGFKGHMLTPSERDQLLAIASSLFVASQLRAQRFQEHSRVPVIRPDVAKWELSVKLHDEDHTVVASNNGPTFNVEVDGSKLNVTSTWNLASPLLSVNVDGTQRTVQCLSPDAGGNMSIQFLGTVYKVHILTKLAAELNKFMLEKVPKDTSSVLRSPKPGVVVAVSVKPGDMVAEGQEICVIEAMKMQNSMTAGKMGKVKLVHCKAGDTVGEGDLLVELE
What is the function of this protein?
This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites.  Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity).  Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity).  Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA (By similarity).  Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (By similarity).
What are the official names of this protein?
Propionyl-CoA carboxylase alpha chain, mitochondrial, PCCase subunit alpha, Propanoyl-CoA:carbon dioxide ligase subunit alpha.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GPMA_METPP
Sequence: MTQLVLIRHGESTWNLENRFTGWTDVELTPTGVAQAQQAGRLLKQAGIDFDTVYTSVLKRAIWTAWHCLDGMDRTWLPVIKDWRLNERHYGGLQGLNKADMAKQFGDEQVLLWRRSYDVPPPPLEANDPRSERSDVRYAKLAANQVPLTECLKDTVARVLPLWYGTLAPAIAAGQRLVIVAHGNSIRALVKHLNNISDADIVGVNIPNGIPLVYDLDANLKPTSKYYLGGADAAAQAASVSALQADG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: DCD1B_DICDI
Sequence: MNLIKLFIICCLLISITVKSFEIENDIDIDFEFDNSFDQSSSSAGSGSDSYDQDKCKGKPNPYPIFNKEPIFIASTANGKLYKTGDDSNQVSILHLYGEAYEMGYAHGTLLKEQVNELIPKFMEFAEIAIKEFIKTKFALRLPEFLIKLIEEFGVNAALDYVASATEQFTPKRFFNELLGLSDSSGIPYQTLLRMHMFPELVKATCSIVGAWSEATINGGLLQVRALDWGLENPLVNYPTLIVYHPQENDGGEFSILSWTSFIGALTGYSQRTGVCEKVWLSYNGTYTHNGMPFYFILRDILQYDNSIYEALNRIYNTPRTCAVYLGVGSNESNTASLLEVSMDVVRVFDDETPFPGFAPPVPEHPLFKDVVYVDKHSQPSTDPCMANSLSQSWSEITAQTLINTMGQMETGDLHSAVYDFKQNLVYVSVATTNIPFPFTNETLPLVSPAYKNQFIQFNMTKLFSEQPPLPPPNNSSSSDSNSNSNSDSSSSSDSNSNSN
What are the official names of this protein?
Protein dcd1B, Acid ceramidase-like protein B.
What are the subcellular locations of this protein?
Secreted.
Protein: RECR_SYNJB
Sequence: MYTRPLARLIEELQRLPGIGSKTAQRLALHLINRPAGEIEALAKALLEAKQTVRHCSICFNWSAEDPCEICRSPQRDPSLWCVVADVKDLIAMERTREFKGLYHVLGGLISPMNGIGVDQLHIRELVARVAREKPQELIFAISPSVEGEVTMHVVKDYLKPVAPTLRMTRLAFGLPMGSELEYADEVTLARALEARQEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ARGB_BACMK
Sequence: MSDYIVVKCGGSMLDQLNDVFFDCIKKLQQKYKVVIVHGGGPEIDAKLKDCNIKVEKRDGLRVTPREVMDIVQMVLCGSTNKKLVMNLQKHNLLAVGCSGCDGNLLQVQPVSKEIGYVGEVSYVETALLKGLINMNYIPVIAPIGINENEIYNINADNAAAGIAAALSAKELIFITDVDGILHEGKLVKKTDEFEIDTFIEKGVITGGMIPKVQAALASLKMGVQKVSVVNGTKDFAEVTGECIGTTVTKGVNIV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS181_ROSCS
Sequence: MTDDQTRRSAGASRRRFGARRKVCAFCADKIRVVDYKDVKRLQRCMSERGKILPRRRTGVCARHQRSLTVAIKRARHMALLPFVAAHMHS
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.