PharMolix/UniProtQA huggingface dataset:
Protein: RF2_AERHH
Sequence: MFEVNPVLNKLKELSERTELLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERVALENVVGTIDTLTQGADDVAMLVELAVEGEDEDTFNEAVAEADVLETKLVDLEFRRMFSGQHDPSDCYIDIQSGSGGTEAQDWANMVLRMYLRWGDAHGYKPELIECSEGDVAGIKSATIKFTGEYAFGWLRTETGVHRLVRKSPFDSGGRRHTSFCSVFVYPEIDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGVVVQCQNDRSQHKNKDQCMKQLKAKLYELEIQKQNAEKQALEETKSDIGWGSQIRSYVLDDARIKDLRTGVETRNTQAVLDGDLDKFIEASLKSGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DKF1_CAEEL
Sequence: MDGSQGSTDYGDHVVLRYGGTREMVPLIRHEQMLDMLMERARQIVQGFGNLDTRNMYLFRHEYNSPTLLYPITSASQITSGSILEIILVDRTEAAVIPHVVEPESYMRPTFCDFCGEMLTGLMRQGVKCKNCNGNFHKRCSNAARNNCGAPGAPGAQPSRPPILPPIPTTPTGFPVAALSTPTGLPHTLIEHSYRQFTVCKVCDHLLVGLVKQGLKCRDCGVNVHRKCAMELASNCVLSENAISRVNFTDPEGPGSSSSDNIPLFRLPGQVGTRATEKKKLEGWMMHFILSDPERRLKHYWMMQSNAIHLYNEYSEGIGVNPNRVYRIIPLAEITSVVQNNGKSVLAKHPPHCFEIRTTTNTVFCVGEDYHAFSGGPPKKIPRSMSVRPSSNTTMWFQFIKESLQPPSRNEDNAEQALEFANLYQVLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQTCHPGIVCLEFMCETKDKIFVVMEKMNGDMLEMILSQELGRLNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARFIPESQFRKTVVGTPAYLPPEVLQRKGYNKSLDMWSVGVIIYVTLSGTFPFNEGEEISEQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCLDHGWLKGEQLYRDLRDLEVRLNTPRYLTSPQDDILYGTLVNP
What is the function of this protein?
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, independently of PKC (PubMed:16613841, PubMed:16613842).  Role in the regulation of growth and neuromuscular control of movement (PubMed:16613841, PubMed:16613842).  Involved in immune response to S. aureus bacterium by activating transcription factor hlh-30 downstream of phospholipase plc-1 (PubMed:27184844).
What are the official names of this protein?
Serine/threonine-protein kinase dkf-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Translocation to the cell membrane is required for kinase activation. On activation, the protein may migrate back to the cytoplasm.
Protein: IIGP5_MOUSE
Sequence: MATSRLPAVPEETTILMAKEELEALRTAFESGDIPQAASRLRELLANSETTRLEVGVTGESGAGKSSLINALRGLGAEDPGAALTGVVETTMQPSPYPHPQFPDVTLWDLPGAGSPGCSADKYLKQVDFGRYDFFLLVSPRRCGAVELPPSLLRSCARGRSFTLCAPRWTRIWRPPAARGPRVSARLQLLQEIRDHCTERLRVAGVNDPRIFLVSNLSPTRYDFPMLVTTWEHDLPAHRRHAGLLSLPDISLEALQKKKDMLQEQVLKTALVSGVIQALPVPGLAAAYDDALLIRSLRGYHRSFGLDDDSLAKLAEQVGKQAGDLRSVIRSPLANEVSPETVLRLYSQSSDGAMRVARAFERGIPVSARWWPGVSASARSTPCSRAVSMRWLRTPNASASKPWRKMSPRGVR
What are the official names of this protein?
Interferon-inducible GTPase 5, Immunity-related GTPase cinema 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.
Protein: HOLE_ECOL6
Sequence: MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQPEHLRSWFRERLIAHRLASVNLSRLPYEPKLK
What is the function of this protein?
The exact function of the theta subunit is unknown.
What are the official names of this protein?
DNA polymerase III subunit theta.
Protein: ASSY_SALTY
Sequence: MTTILKHLPAGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDESVKIPAEVVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHSHGRQLGKLLYQGRWFDSQALMLRDGLQRWVASQITGEVTLELRRGNDYSILNTVSDNLTYKAERLTMEKGESVFSPDDRIGQLTMRNLDITDTREKLFGYAKAGLLTASSATGLPQVENLENKGK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF5A_THEVO
Sequence: MSWQEAEVRELKVGRYILIDDVPCKIVEITMSKPGKHGEAKGRIVAIGVFDNQKRSVVYPVKHKVKIPIIEKKNAQVLSVMNNEAQLMDSETFETFVLPLDPEIADKVKPGMEVPYWEAMGVRKIMLQN
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK14_GNEPA
Sequence: MIQSQTFLNIADNSGARKIMCIRVVGTTYQKYAYIGDIIIAIIKEVVPNTKMEKSEIVRAVVIRTSKEFQRDDGMRIRSDDNAAIIIDQKGNPKGTRVFGPVLQELRQWNFTKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: OSB3_DICDI
Sequence: MGKSDRKLTEENSIENGVKPGKLTEEEMDAIDNSSQSKIVAIASMAKRLGLGLGSDLSQVEYPSSFIAPFSTLNFFSNNFANHFNILLRANKIENEMDRLIEVFKYSTTIHKIPEDCMKVPLNAVIGETQSLNFQTPDLNSPNDLISDNYLITEQVSELPPNTATCIYNKKEGVKALFNHESKIVFQITNVKTPTTGRKYVRFDKFDEEYDIEFPVLHSRFMRGFVEYCGEGSIKSNKSKCFVSTNYIAKPLIGGNYHAYEAKVYNGIDSKPIYKISGQWDGESKITNLKTNETKPFFKNITTTTNFTPTILNTDSSVVWGKIIQSVAQGKPINLAREKSKIIENQKTLNWAPSQFFLNLEMGVWEPKLLND
What are the official names of this protein?
Oxysterol-binding protein 3, OSBPc.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
Protein: PURA_VIBPA
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRDNVKCVIGNGVVLSPEALLKEMKPLEERGIPVRERLFISEACPLILPYHVAMDQAREIARGKKAIGTTGRGIGPAYEDKVARRGLRVGDLFDMEAFAEKLKEVMEYHNFQLVNFYKAEPVSYEAVLEEAKGYAELLTSMVIDVTDELDAARKRGDKIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVAAGSGFGPRHIGYILGIAKAYCTRVGAGPFPTELYDGLEKQDPVGKHLGTVGHEFGATTGRLRRTGWFDAVAMRRAIQINSVSGFCLTKLDVLDGLEELKICTGYKMEDGSVLEVSPMAAEAFEKATPIYETMPGWSENTFGAKSLDALPQAALNYIKRIEELTGVPVDIISTGPDRNETIIKVHPFEA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSTL3_RAT
Sequence: MRPGALWPLLWGALVWAVGSVGAVMGSGDSVPGGVCWLQQGKEATCSLVLKTQVSREECCASGNINTAWSNFTHPGNKISLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPHCECVSNCEGVPAGFQVCGSDGATYRDECELRTARCRGHPDLRVMYRGRCQKSCAQVVCPRPQSCLVDQTGSAHCVVCRAAPCPVPPNPGQELCGNNNVTYISSCHLRQATCFLGRSIGVRHPGICTGGPKVPAEEEENFV
What is the function of this protein?
The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN.  Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B.  Involved in bone formation; inhibits osteoclast differentiation.  Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma.  The nuclear form is probably involved in transcriptional regulation via interaction with MLLT10 (By similarity).
What are the official names of this protein?
Follistatin-related protein 3, Follistatin-like protein 3, Follistatin-related gene protein.
What are the subcellular locations of this protein?
Secreted. Nucleus.
Protein: GLYA_POLNS
Sequence: MFDRQNTLAKTDPQLWEAIQNENKRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEFIDVAEQLAIDRVKALFGAEAANVQPHCGASANQAVFLAFLKPGDTFMGMSLAEGGHLTHGMALNMSGKWFNPIAYGLDKNEEIDYEQMERLAREHKPKLIIAGASAYSKKIDFERIGKLAKEVGAIFMVDMAHYAGLVAAGVYPNPVPHADIVTSTTHKSLRGPRGGIILMKAEHEKAINFAVFPGLQGGPLMHVIAAKAVAFKEAAEPGFKDYQKQVVANAKALAETLIARGLRIVSGGTDSHVMLVDLRAKSMTGKEAERVLGEAHITCNKNGIPNDPEKPMVTSGIRLGSPAMTTRGFKEAEARQVGNFIADVLDNPNDPANIAKVRAQVAELTKRFPVYD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBX_DROHY
Sequence: SGAAAAQTAAASSLHQASNHTFYPWMAIAGESTADPIKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTR
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Binds the consensus region 5'-TTAAT[GT][GA]-3'.  This homeotic protein controls development of the cells in the posterior thoracic and first abdominal segments.  It activates the synthesis of the decapentaplegic (DPP) growth factor (By similarity).
What are the official names of this protein?
Homeotic protein ultrabithorax.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYN1_AURPU
Sequence: MKFFATIAALVVAAVAAPVAEADAEASSPMLIERAGPGGINYVQNYNGNLGQFTYNENAGTYSMYWTNGVSGDFVVGLGWSTGAARSITYSSSYTASGGSYLSVYGWINSPQAEYYIVESYGSYNPCGAGQSGVTQLGTVVSDGATYTVCTDERVNEPSITGTSTFKQYWSVRQTKRTSGTVTTGNHFAYWAKYGFGNSYNFQVMAVEAFSGTGSASVTVS
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Hydrolyzes xylans from oat spelt and birchwood at similar rates, but it has no detectable activity toward Avicel or carboxymethyl cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase 1, Xylanase 1, 1,4-beta-D-xylan xylanohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y506_PROM0
Sequence: MAESFSFDVVSDFDRQELVNTLDQVKREISQRYDLKDTDTLVDLDKENIFIITNSELTLNAVNDIIRQKAIKRNLSLKIFDYGDIEIVSGNKIKQTILLKQGIKQEIAKKISKNIRDQIKKINVSINGETLRVASKSKNDLQLAIKIVSELEESLNIPLKANNFR
What are the official names of this protein?
UPF0234 protein P9301_05061.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RS9_STRP4
Sequence: MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADLRLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAGLLTRDSRKVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: YBJL_ECOL5
Sequence: MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECB_CERS4
Sequence: MTDANGAPAEAAPQIRMQVLAQYVRDMSFENMVAQKGLQGGDVQPDIQVQVSLDARKRSVEHQYEVITKFKVTSKNKSGSAETLFLLELDYGGIFHVENVPEDQLHPFLLIECPRLLFPFVRRIISDVTRDGGFPPLNVDTVDFLALYRMELARRAEAQKAAQPVQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH38_RAT
Sequence: MDEELPDAVVFKDQNFSSDLLRQLNGLRQSKILTDVSICSGACEVPCHRNVLASSSPYFRAMFCSHFRESREAKVQLKGISSTTLEQVIAYVYTGEVHISAANVLPLMEAAAMLQYPRMFEACSSYLQSQLAPSNCLGLVRLAEILSCDSLKKKAREVALTYFPEVAASADLKELCVMELRDYLGDDKLCGEEEKVFEALMAWVKHDLQARWRYMQELLQQVRLQYIHPAFFHHFIASDALLQSSPACQAILEMAKKQIFSLYGPSAQDCKLWHTPPRSSYQDFLLLLGGRKDNQQTTRDVLLYSIQTGQWQSLAKLPTRLYKASAVTLHRSVYVLGGMAVREGKGLISCSVYIFSMKLNQWRMGEPMLAARYSHRSTTHRNFIFSIGGTGEGQELLGSMERYDSIRDVWESMADMPMAVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYHISRNTWYKMETRMIKNVCAPAVVLGEKIIIVGGYTRRILAYDPQSNKFVKCADMKDRRMHHGATVMGNKLYVTGGRRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHTLFDHACLTLQCIPHMTSLS
What are the official names of this protein?
Kelch-like protein 38.
Protein: KUP2_LACAC
Sequence: MNKITKKQKMSFAGLLIAIGIVYGDIGTSPLYVMKSIVTENGGIANVNRELIVGSISLILWTVTLLTTVKYVMIALKATNHGEGGIFSLYALVRKRAKWLVIPALIGGAALLADGTLTPAVTVTTSIEGLKNMRFGDVIPVPSQEVVIMITIIILVILFSIQRMGTSVIGKAFGPIMLIWFTFLGVVGIANLSHDWSLLEAINPIHAIRILVSPANKVGILILGSVFLATTGAEALYSDVGHVSKANIIGSWPYIFVCLSLNYLGQGAWILHNVSYHAGNGDFNPFFEVVPSNLRLFAIALATIAAIIASQALITGSFTLVAEASSLKFLPRMNIIYPSTEKGQIYIPLINKMICVVTVAIVFLFRTSHHMEAAYGLAITVTMLMTTILLFEYLGKKGKPLYLRVIFLIAFAFIEGMFLISSLTKFLHGGYVTVLIAGFILVIMYVWFYGNKIRDKREAKNAYVRLDEYTEMLTDLSHCEDYPVYATNVVYMAKVKYNKFIKREMLYSILDKRPKRAKAYWFVTVNVTNEPYTAEYAVNTYGTKNVINVQLYLGFRKQTSVNVYLRQIVHELIADGTIEAQPQRFTTTPGRDVGDFSFVIVNDVISPLTKLTGYEKFMVEARVWLQNLSSNPASWFGLEYADTVVERVPLILGKHQESYIKRIKPKKQTKK
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAK1_YEAST
Sequence: MSAKSFEVTDPVNSSLKGFALANPSITLVPEEKILFRKTDSDKIALISGGGSGHEPTHAGFIGKGMLSGAVVGEIFASPSTKQILNAIRLVNENASGVLLIVKNYTGDVLHFGLSAERARALGINCRVAVIGDDVAVGREKGGMVGRRALAGTVLVHKIVGAFAEEYSSKYGLDGTAKVAKIINDNLVTIGSSLDHCKVPGRKFESELNEKQMELGMGIHNEPGVKVLDPIPSTEDLISKYMLPKLLDPNDKDRAFVKFDEDDEVVLLVNNLGGVSNFVISSITSKTTDFLKENYNITPVQTIAGTLMTSFNGNGFSITLLNATKATKALQSDFEEIKSVLDLLNAFTNAPGWPIADFEKTSAPSVNDDLLHNEVTAKAVGTYDFDKFAEWMKSGAEQVIKSEPHITELDNQVGDGDCGYTLVAGVKGITENLDKLSKDSLSQAVAQISDFIEGSMGGTSGGLYSILLSGFSHGLIQVCKSKDEPVTKEIVAKSLGIALDTLYKYTKARKGSSTMIDALEPFVKEFTASKDFNKAVKAAEEGAKSTATFEAKFGRASYVGDSSQVEDPGAVGLCEFLKGVQSAL
What is the function of this protein?
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.
What are the official names of this protein?
Dihydroxyacetone kinase 1, DHA kinase 1, Glycerone kinase 1, Triokinase 1, Triose kinase 1.
What is the protein family that this protein belongs to?
Belongs to the dihydroxyacetone kinase (DAK) family.
Protein: KUP_AERS4
Sequence: MSCDNKQALSGVTLAAIGVVYGDIGTSPLYTLRECLSGQFGIRAEPAAILGFLSLIFWLLILVVSVKYLSFVMRADNAGEGGILTLMSLATRNASPRWTPVLIILGLIGGSFFYGEVVITPAMSVMSAIEGLSLMAPSLDPYIVPLSVLVLTLLFAIQKHGTAMVGKLFAPIMLTWFLTLAVLGLRSIIQNPEVLGALNPIWALRFFAEYQTTSFFALGAVVLAITGVEALYADMGHFGKNPIRLAWFVVVLPSLVLNYFGQGALLLDNPAAIANPFFLLAPKWALLPLLVLATMATVIASQAVISGVFSLTRQAVRLGYLSPIRIVHTSEQESGQIYIPVINWILYISVVIVIMSFEHSSNLAAAYGIAVTGTMVLTSILFCSVAKNSWHWPTYLVAALFALLLAIDVPLFAANLGKIFSGGWLPLTLGAVMFTLMTSWKSERFQLIRRLNEHGNSLEPMIASLEKSPPTRVAGTAVYMSRVVNVIPHALLHNLKHNKVLHERIILLTLRVEDVPYVHNVRRVCIEQLSPTFWRVVASYGWRETPNMEEIFHRCNAEGLSCRMMETSFFMAHESLIMKERPCAANCLCCCSATPCAQRISSRSRPIG
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STMN1_HUMAN
Sequence: MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD
What is the function of this protein?
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules.  Prevents assembly and promotes disassembly of microtubules.  Phosphorylation at Ser-16 may be required for axon formation during neurogenesis.  Involved in the control of the learned and innate fear (By similarity).
What are the official names of this protein?
Stathmin, Leukemia-associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein p19, pp19, Prosolin, Protein Pr22, pp17.
What is the protein family that this protein belongs to?
Belongs to the stathmin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYC_CHLAB
Sequence: MRQSSDNRQNLYLYNTASRTKELFSPSNDPVKLYTCGPTVYDYAHIGNFRTYIFEDLLKRILLFFGYSVKHVMNITDVDDKTLAGACKNNISLDTYTAPFIQAFFKDVATLHILPADAYPRATHYIPQMLVAIRKLLDDGIAYIGQDHSVYFSIKEFPSYGKLSQLQLQNLQCCSRIASDEYDKENLSDFVLWKAYDKHRDGHIYWESPFGKGRPGWHLECSIMAMELLGPSIDIHAGGVDNIFPHHENEIAQSESLSHQPFSRYWLHSEHLLVDGKKMSKSLGNFFTLRNLLDRGFSGAEIRYMLLQSHYRMQLNFTEEGLMACRQALKRLRDFISRLESPYPESATISEGIDQCGQRFLQDFSNAIANDLNIAAALASLFDFIHQTNSRIDQSHFTQADSHYVLDILKKINTVLGVIPFSTSLEIPSEVARLVEEREIARKEKNWKQADVLRNQIASFGYVVEDTKSGPKVKKY
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ARTS2
Sequence: MKSAVENLTPTRVKLNVEVPFEELKPSIDEAYKTVASQIQVPGFRKGKVPAKLIDQRVGRGYVLETAINEGLNGWYQEAVQETGIRPLSRPEVEITEVPDPTATDGELKFHAEVDVRPEIELPDYSGIKVEVAAAESSEADVDKALDELRGRFGTLKSVDRPAADGDFLTIDITASIDGAEVDSASGLSYQVGAGTMLEGLDEAVTGLSADEDAIFDTTLVGGDHAGEAAQVKVVVKSVKERELPEADDDFAQLASEFDTLAELREDLAKQAAESKVVEQGVEARDKVLDKLVELVEVPVPASVVEEQLEQHFKAENSHGDGEHDTEEHRAEVKANTERAFQNEIILDAIADKEEVGVSQNELIDYIVTTASQYGMDPNQFAQIIDQSGQVPMMVSEVRRRKALAVVLGQAEVTDSEGNKVDLSDFVRPGGEEEAAEAEAAPAVDSDAVEGEAATEEAAPSDDPAAVKF
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: GLMU_GEOTN
Sequence: MVKRYAVILAAGQGTRMKSKLYKVLHPVCGKPMVQHVVDQVSKLGVEKTIAVVGFGAEQVKEQLGAQCEYALQEKQLGTAHAVMQAAPHLQNLEGITIVVCGDTPLITAETMEALLEHHMTAGAKATVLTAIADDPTGYGRIVRNSDGHVEKIVEHKDANEQEREIREINTGTYCFDNRMLFQALTKVTNNNAQGEYYLTDVIEIIKADGGIVSAYQAPSFDETIGINDRIALAEAERIMRDRICRQHMKNGVTIIDPACTYISAEATIGRDTVIYPGTVIEGKTVIGEDCTIGPHSEIKNCHIGHRTSIRHSVAHDSEIGDDVTIGPFAHIRPLSKIDDEVRIGNFVEVKKSTFGKGSKASHLSYIGDAEVGADVNLGCGSITVNYDGVHKYRTKIEDGAFIGCNANLIAPVTIGQGAYVAAGSTVTDDVPGRALAIGRARQVNKENYVDRLRGKKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_SHEHH
Sequence: MPIIKVRENEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAVKRLAKKLSRENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL6_LAWIP
Sequence: MSRIGKLPIMIPAGVEITFGEKNISIKGPKATLVTPKCELLSYEHKEDKIILTCNFDTRESLAQYGLRRTLLANCIEGVTKGFSKTLEVIGVGYRVSVKGNIVELSVGYSHPVHIELPDGITAKAEGQKLTIMGSDKVLVGEMAARIRRIRKPEPYKGKGIKYESEIIRRKAGKSGGKGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: 3SOF3_NAJAT
Sequence: MKTLLLTLVVVTIVCLDLGYTRKCHNSPLSLVYQTCPIGQNICFKINVKEAPSIPVKRACAATCPKSSALVKVVCCKTDKCN
What is the function of this protein?
Has low cytotoxic activity.
What are the official names of this protein?
Cytotoxin homolog Clbp-3, Cardiotoxin-like basic protein 3, CLBP3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XV sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: NUDL_YERPS
Sequence: MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: ANGP4_BOVIN
Sequence: MPSPPAMLLGGLLLIVASTTVAQRRGQEAAGRRRAHRVQHGQCSYTFVLPEPEPCPPEPEAFGGSNSLQRDSPAATLNLGDWPSQRMRQLEKMLENNTQWLQKLERYIQVNLRLELAQAQQHMVQNQTATMLELGTSLLTQTTAQTRKLTDVEAQVLNQTSRMEIQLLETSLSTNKLEKQLLLQGHELHRLQGHNSALETRVQALETQQQAELASLSGEKERLRRLLGRQSGALAGLERTLRAASSNSSLLQRQQHQLLESVQRLVRVMAQGPASMRAADQLFQDCAEIQRFGANASGIYTIHVANVTEPRKVFCDMEASGGGWTLIQRRENGSVNFQRNWKDYKQGFGNPAGEHWLGNEVVHQLTSRATYSLRVELQDWEGNEAYAQYEHFQLGSEAQLYRLSLSGYSGSAGRQSSLVLQGTNFSTRDADNDNCLCKCAQMLSGGWWFDACGLSNLNGIYYPARHHVRKLNGIRWHYFQGPSYSLRTTRMMVRPSGI
What is the function of this protein?
Binds to TEK/TIE2, modulating ANGPT1 signaling.  Can induce tyrosine phosphorylation of TEK/TIE2.  Promotes endothelial cell survival, migration and angiogenesis (By similarity).
What are the official names of this protein?
Angiopoietin-4, ANG-4.
What are the subcellular locations of this protein?
Secreted.