PharMolix/UniProtQA huggingface dataset:
Protein: RL3_TROW8
Sequence: MARALLGTKVGMTQIWSGRRVVPVTAVAVTTNVVSQVKAPEKDGYSRLQIATGAIDPRRVNRPRKGHFAKAGLTPRRFIREVDSEGSLGDEFGPEIFQEGQLVDVVGKSKGKGFSGTMKRHNFQGVSATHGSHRNHRKPGSVGASSTPSRVFKGTRMAGRLGSSRVTVHNLRLVKIDSENGLLLVEGAVPGSSGSPVIIRDAVKGVPIVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RS15_SHEB9
Sequence: MSLSTEVKAKILADFGRCENDTGSTEVQVALLTAQINHLQAHFKEHIHDHHSRRGLLRMVSSRRKLTAYLKRTDVARYTALIQKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ALY2_SCHPO
Sequence: MRGELNIPALSRFGKSISASLHHQNGSSRDDNDSNPYENRSSNSGLNRRNSVFGLPSSGLSSRLSKPSLSSINNSNNSSSNTGGNVLPNPALTPVRNMSNKPPLTWSPSSANLFGTSKVTSIIGNNVSDVVPPVIKKALASSHGGGMSLSIVLLEPVLYLAGFDLNECQIENPALLRGALVLRVAKPANIRGISLSFTGRSRTEWPEGIPVKGHDTYEDKVIISHNWKFYEPTMKDADAPQHGADVARLVGEQLPLPSSAAASLRGYSVFAPGEYTYNFDLAIPNCFPESVEAKMGWVRYFLEATVERFGTFKSNLNGRTPVQLVRTPSPASLSSSELINISRDWDERLHYELQVSGKSFRLGEVVPITFRFLLLDKVRLYKLSISVVESSEYWCRSRKFHRVDPKRRVLLAERSAKHQNTDNLFETPDEGDGLSSAVFNFNVALPTCLVKERDRLTFDTTYKYIKVRHRLKALLVLSIENTENPEKRKYFEINIETPVRILSCRCVKDSTLLPPYESSSQGDNQVLLPCPCRLATTHVEPTEVTAFTTQSVLASSAPSAGRPAAAQISRPAQLFRIPSTNPPPFDGDVCPPACNTPPPNYDELFDVLSSISIQDCETDRANDDTILNNRVRRSGTIREEAPHRSLSRTVSRSFEIPR
What is the function of this protein?
May regulate endocytosis in response to extracellular stimuli.
What are the official names of this protein?
Putative arrestin-related trafficking adapter C2D10.04.
What is the protein family that this protein belongs to?
Belongs to the ALY1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at the cell tip and barrier septum.
Protein: YM085_YEAST
Sequence: MEFYLSSDCASLARYVSKVVYLEDNDIAHIYDGELHIHCSKIGSEDFSFRTVQKLELELSKIKKGPYDNFMQKEIYEQCETTKNVMRGRVDAFTNRVVLGGLENWLTELRRAKRIIMIASKASFHSCLAARPIFEELMEVPVNVELALDFVDRNCCIFRNDVCIFVSRSGETTDTINALNYCIKKEAVTIGVVNCSGSSISRFTHCGVHTNTGPEKGIATTKSYTSQYIALVMIALWMSEDLVSKIERRKEIIQALTIVPSQIKEVLELEPLIIELCDKKLKQHDTFLLLGRGYQFASALEGASKMKEISYVHSESILTNELGHRVLAVASDNPPIIAFATKDAFSPKIASCIDQIIERKGNPIIICNKGHKIWEQDKQKGNVVTLEVPQTVDCLQGILNVIPLQLISYWLAIKKDIGVDLPRDSAMSAPDI
What are the official names of this protein?
Uncharacterized protein YMR085W.
Protein: ABHD2_MOUSE
Sequence: MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKRTYPQTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKSQCSDTEQMEAELE
What is the function of this protein?
Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane.  Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA).  Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester.  Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (By similarity).  Involved in acrosomal reaction (Probable).  May also play a role in smooth muscle cells migration (PubMed:15721306).
What are the official names of this protein?
Monoacylglycerol lipase ABHD2, 2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 2, Acetylesterase, Lung alpha/beta hydrolase 2, MmLABH2, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome membrane. Note=Absent from the sperm flagellum.
Protein: ZD12A_DANRE
Sequence: MNKSLFKSGCLVRTAHVILTWIITLILFLHNTDLRRCQERGDLLQPLVFSSVLLLSVLLYFTVSLMDPGFVLSDSQTETASGDGDEELEAMIPQEQNSIKQRRCGYCFLLQPMRARHCKWCKRCVRRFDHHCPWIDNCVGELNHRWFLLYLCVQFTAVCWGLQSAWSGFISAPSWQQWFTQNVFLLVAFAVTAVFSVVLLLLLCIHAYLASVNCTTWEFMSRHRILYLKHVDSEENPFDRGVFCNLWSFCCVCGTVAWEKMYIRHNNASV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (By similarity).  Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyric acid receptor clustering (By similarity).  Acts as an inhibitor of the NLRP3 inflammasome by mediating palmitoylation of NLRP3, thereby promoting NLRP3 degradation by the chaperone-mediated autophagy (CMA) process (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC12-A, Zinc finger DHHC domain-containing protein 12-A.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ALMT5_ARATH
Sequence: MGGKMGSVPEQNTEKLLWQSSDVADSRDSKFRCCSWRALYEAPAKLYALGHSDRRKLYFSIKMGIALALCSFVIFLKEPLQDASKFAVWAILTVVLIFEYYVGATLVKGFNRALGTMLAGGLALGVAQLSVLAGEFEEVIIVICIFLAGFGASYLKLYASMKPYEYAFRVFKLTYCIVLVSGNNSRDFLSTAYYRILLIGLGATICLLVNVFLFPIWAGEDLHKLVAKNFKNVANSLEGCVNGYLQCVEYERIPSKILTYQASDDPLYSGYRSAVQSTSQEDSLLDFAIWEPPHGPYKTFNHPWKNYVKLSGAVRHCAFTVMAMHGCILSEIQASPEKRHVFSNELRRVGNEGAKVLRLFGEKVEKMEKLSLSLGEILKDVQRAAEALQMKIDSKSYLLVNSESWAAIKEQAEAEEARENDQEAKDDETKVIKSLSQIWDTNNNNNHQSNDQSQHWMSTESMMLKNREMWPSMSFIDGTVVNEIECKVYESASSLSLATFASLLIEFVARLQNIVNAFEELSTKAGFKDAVDQIPKV
What is the function of this protein?
Malate transporter.
What are the official names of this protein?
Aluminum-activated malate transporter 5, AtALMT5.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter (TC 2.A.85) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL5_ANAD2
Sequence: MAARLKERYDKQLRAELMKELGFANPMQAPRLEKIVVNMGLGEAINNGKIIDASVEQLAAITGQKPVVTRARKSIANFKLRQGQSIGAMVTLRGDRMYEFFDRLVSIALPRVRDFKGVSPKAFDGKGNYTLGVREQIIFPEINYDKVEKIKGLNITVVTTARNDEEGRALLRHLGMPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ODO1_MESAU
Sequence: MFHLRTCAAKSVHKSWDIFFRNTNAGAPPGTAYQSPLSLSRLGFYGLHESDLDKSTRFEEFLQRGRLNVLANVIRYHLGMYHRRSSPYPTDVARICEEAFTRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVYYDLTRAKPVWYAGRKTHLTELQRFLDTAFDLDAFKK
What is the function of this protein?
2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex (OGDHC), which mediates the decarboxylation of alpha-ketoglutarate.  The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion.  A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.
What are the official names of this protein?
2-oxoglutarate dehydrogenase, mitochondrial, 2-oxoglutarate dehydrogenase complex component E1, OGDC-E1, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Note=Mainly localizes in the mitochondrion. A small fraction localizes to the nucleus, where the 2-oxoglutarate dehydrogenase complex is required for histone succinylation.
Protein: PRMA_BACSU
Sequence: MKWSELSIHTTHEAVEPISNILHEAGASGVVIEDPLDLIKERENVYGEIYQLDPNDYPDEGVIVKAYLPVNSFLGETVDGIKETINNLLLYNIDLGRNHITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWEEYTPVHTDELIIEMDPGMAFGTGTHPTTVLCIQALERFVQKGDKVIDVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNLKLNKVSDIAQVKQNNLLDGIEGEHDVIVANILAEVILRFTSQAYSLLKEGGHFITSGIIGHKKQEVKEALEQAGFTIVEILSMEDWVSIIAKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOXV_AZOVI
Sequence: MSALEALAGRLHVEVRLQDGVIRAVDTRLQRPLPQISRLLVGQTAEAALRRLPLLFGLCAAAQQVAALRALERAAGWAAIAEVEEGRTRLGELESIRESLLRLVQVWELPVPLERLKALLALCRRAAARLQALTAFRAAPLPADAELEGTLAALAAAWADLQPPAPADWLRPRLDRWQEVALGGPPPQAFTADELPALLAQLRASDARAEIAGQPRLGGPAASAGAQATASAQIEQHVGALLRRTAQAIDSLQSPPAPPAVAGLAAGEGVGLARTARGWLLHRVCLDDGAVGTWQLLAPTDWNFHADGPLRRRLCGVRVAAGEVEALLRELILALDPCVAFEVKIVHA
What are the official names of this protein?
Hydrogenase expression/formation protein HoxV.
Protein: CH602_STRAL
Sequence: MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPMALKRGIEKAVEAVSSALLEQAKDVETKEQIASTASISAADTQIGELIAEAMDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIVNSKIGNVKDLLPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLGDIAILTGGTVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGAGDTDQVNGRVAQIRAEIENSDSDYDREKLQERLANVAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQASSVFEKLELEGDEATGAAAVKLALEAPLKQIAVNGGLEGGVVVEKVRNLSVGHGLNAATGQYVDMIAEGILDPAKVTRSALQNAASIAALFLTTEAVIADKPEKAAAAAPGGMPGGDMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2, HSP56.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_PEA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKNTK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: S17B1_XENLA
Sequence: MSSPDCGYSSDDQIQGSCSVPMMMGQYQWTEPLTVFQDLKPKRDEGSADSRSKAEGRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKSLTLATKRPFVEEAERLRVQHIQDYPDYKYRPRRKKQVKRMKREEDGFLPSANFPGSQIMDNNVMVGENYRMQYSAQNHQQNQLPPAGYFEGHNSMGYYYRDYSVPNYHISQNSSGYDSPPAQDEYQALSYSFNSSYMPYQQNATTPVMAKQMAVTQNIPQESPEHGMMASPQMYNRQMYVSECAKTHPMAQTEQHFPSYQSQKTVRQNYLQSQQDGHLESDIDKTEFDQYLMYEPKADMEIIYTIDQDSGAYSTNLLPSLITEANNVCYYDYCGV
What is the function of this protein?
Transcription activator.  Doesn't appear to bind to the consensus 5'-AACAAT-3' DNA binding site, but binds 5'-ATTGTT-3'.  All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in function.  In addition, the sox17 proteins have distinct but overlapping roles in later gut development.  Acts downstream of vegt-signaling in endoderm differentiation to induce a range of endodermal genes both directly and indirectly.  Also represses wnt-responsive genes to inhibit wnt/beta-catenin-mediated signaling.
What are the official names of this protein?
Transcription factor Sox-17-beta.1, SRY (sex determining region Y)-box 17-beta.1, Transcription factor Sox-17-beta, XSox17beta.
What are the subcellular locations of this protein?
Nucleus.
Protein: VIRB2_BRUA2
Sequence: MKTASPSKKSLSRILPHLLLALIVSIAAIEPNLAHANGGLDKVNTSMQKVLDLLSGVSITIVTIAIIWSGYKMAFRHARFMDVVPVLGGALVVGAAAEIASYLLR
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.
What are the official names of this protein?
Type IV secretion system protein virB2.
What is the protein family that this protein belongs to?
Belongs to the PtlA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLCB2_HUMAN
Sequence: MSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTELEEEEVEEEEEEESGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALAPTSNGSPAARAGAREEAMKEAAEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGEGPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKESVRACLRTCFPSEAKDKPERACECPPELCEQDPLIAKADAQESRL
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, Phosphoinositide phospholipase C-beta-2, Phospholipase C-beta-2, PLC-beta-2.
Protein: TRPA_CYAM1
Sequence: MLIAYLTAGAPDINTTKEAVMKLAKKGADVIEIGVPYSDALADGAILQKASKQALMNGFHLDHLWNLLSEVNEIEVPLVILAYYNQIWHYGVEKWVKKLVAHNVKGLIVPDLPYEESKTLRQICDRYGLNIIWLISPTTNKTRAQELARACKDWIYVISRTGVTGLETEFDKQIPKLIGELKKVTKAPIALGFGISKSEQVKLVKSWGADGVIIGSACMQILLEKGVDQLSEWISVMKKSFCP
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1170_METST
Sequence: MVLIIDGQTSGLAGNMFIGAFIDLGANKDDIINVIKTYANEFGDIDITITKQPKSGIMCTYAQINTTDKSTRHYNEIIEKLDDITQKHYPDNEIILKTINLSKKIFKTLAIAESKVHGKSLDQLHFHEVGCADAVADIIGSSYAYYLLNLDKEKVYSLPVATGSGTVKTQHGILPVPAPAVLNILKNVPTIGGCVNTEICTPTGCAILVNITDEYVSSYPYVTRKTIGYGAGKKDLEVLNALRLVHANSVTKNDTVTILETNIDTLSGEVLGSLYDKLLSEGARDVTITPTIMKKNRPGQIIKVICRNNDAQHITNVLMEETGTLGVRVIPTVHRGVAIRENIHEKININGTWEDVRFKIGYINDKIIKCTPEYDDIKKIANKTSIPIKDLIKYVEMEYRINNRGD
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: HSLO_STRPC
Sequence: MDKIIKSIAQSGSFRAYVLDSTETVALAQEKHNTLSSSTVALGRTLIANQILAANQKGDSRITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATGEVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNVLLDENDKVKVAGGFMVQVLPGASEEEVARYEKRLQEMPAISHLLASKNHVDALLEAIYGDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQFNESDLEAIINDKA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E13B_VITVI
Sequence: MALTRNRPFVVVLLLGFVIMSTITIGAQSIGVCYGRNGNNLPSASQVINLYKSNGIGSMRIYDPNSDTLQALRGSDIELILDVPNTDLQSLASDASAAATWVQNNVVNYASEVKFRYIAVGNEVLPTGSNAQYAQYVLPAMKNVQSAITSAGLQDQIKVSTATFSAVLGKSYPPSEGSFSDDVSSFINPIISFLAENGSPLLANIYPYFSYTGDTQNIRLDYALFTASGVVVQDGSYQYQNLFDALLDALYAALEKAGGSNLKIVVSESGWPSEGGTAATVDNARTYYKNLINHVKGGTPRKSGAIETYLFAMFDENQKTGLETEKHFGLFTPGQESKYQISFS
What is the function of this protein?
Implicated in the defense of plants against pathogens.
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase, (1->3)-beta-glucan endohydrolase, (1->3)-beta-glucanase, Beta-1,3-endoglucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
Protein: RL5_ECOLC
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: UVRB_MALP2
Sequence: MNTNKNTVFDLKSKFKPSGDQPQAIEKIVKGFKEDKFKSQVLVGATGTGKTFTMANIIQSLNCKTLVLAHNKTLAAQLYSEFKEMFPDNKVEYFVSAFDFYQPEAFLPKTNTYIEKNSQSNNDIEMLNLSALNSLIERDDVIVVASVAAIYASSPPDDFFKNRVAYKKNQVIPIKQVQYELVNLNYQRNDVDVTHGRFSVKGDLMEIGPGFTDEFNYRISFFGDEIEEIAKIDPLTKQVITKLDEIVLPGAEVYLANRDTLEESLKRIKDELTETHKNFLKQNKLIEAQRILERTNHDIESFKEFGFCPGIENYSRHLELRAQGQTPYTIFDYFDKDWLLIVDESHMMVPQIRGMYNTDRSRKETLVEYGFRLPSALDNRPLNFNEFLSKTDKKLYVSATPNEWEIEESQQITEQIIRPTGLVDPIIEIRPTQDQILDIEQELRKQIANKERTFITVMTIRLAEELTEYLRNKNIKVAYLHNELKTIERFKILNNLRKGIYDVVIGINLLREGLDVPEVSKVLILDADKPGFFRSDKSLIQIIGRASRNVNGKVIMYADTITEAMDKAIKETERRRNIQIEFNKKHNITPKTVIKPIALDLSKNDADINIDELISKNKKSKEKIDRTVKKLREEMLAAAKNQEYERAAYIRDIIMELEANKK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_STUS1
Sequence: MQNPQNLIWIDLEMTGLDPDNDVIIEMATIVTDSQLNVLAEGPVIAVHQSDEVLARMDEWNTRQHGGSGLTQRVRESRISTAEAERLTLEFLEQWVPKGKSPICGNSICQDRRFLYRQMPTLEAYFHYRNLDVSTLKELAARWAPQIMEGFKKGGTHLALDDIRDSIAELRHYREHFIKV
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
Protein: CLDN1_HUMAN
Sequence: MDNRFATAFVIACVLSLISTIYMAASIGTDFWYEYRSPVQENSSDLNKSIWDEFISDEADEKTYNDALFRYNGTVGLWRRCITIPKNMHWYSPPERTESFDVVTKCVSFTLTEQFMEKFVDPGNHNSGIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYRVA
What are the official names of this protein?
Claudin domain-containing protein 1, Membrane protein GENX-3745.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
Protein: UPPP_PSEA6
Sequence: MTLTEIIILAIIQGITEFLPISSSAHLILPSVLLGWENQGLAFDVAVHVGSLLAVMIYFRGDIGRMLVAWFGSGFSKNQTDDSRLAWWVIIATIPALIFGFAGKAFIEEYARSALVIACTTIGFGLLLWYADKKAALNKHIYDMTWKSALIVGMAQALALIPGTSRSGITMTAGLMLGLDRESAARFSFLLSIPVILGAGLLATLDLVSAPDAVDWNALIVGAVLSFVSAYACIYLFLAWISRIGMLPFVIYRMLLGVILLLFVFA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YHZD_BACSU
Sequence: MADYFLTVFDPSGNTLVNEQFEAEHEEAAKTHGEALLKEKELHSHTHRLVNAAGKLILFHR
What are the official names of this protein?
Uncharacterized protein YhzD.
Protein: MDTK_ECOBW
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METXS_PSE14
Sequence: MPTVFPHDSVGLVTPQTAHFSEPLALACGRSLPAYDLIYETYGQLNAARSNAVLICHALSGHHHAAGFHSADDRKPGWWDSCIGPGKPIDTNTFFVVSLNNLGGCNGSTGPSSIDPDTGKPLGANFPVVTVEDWVNSQARLADLLGIDTWAAVIGGSLGGMQALQWTISYPDRVRHCLAIASAPKLSAQNIAFNEVARQAILTDPEFHGGSFQERGVIPKRGLMLARMVGHITYLSDDSMGEKFGRGLKSEKLNYDFHSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAANFNDDLAKTFANATAKFCVMSFTTDWRFSPARSRELVDALMAARKDVCYLEIDAPQGHDAFLIPIPRYLQAFGNYMNRISL
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.