PharMolix/UniProtQA huggingface dataset:
Protein: ARGJ_PHYPA
Sequence: MAMVSSCRLCLRTDSLYLAIEQSAAQANSLPRSSCSVVPRRTQIICPQLQVLPNALKSLQPGHGLKRLKEGNVFAVRASTTTDTDVNVDADAVAPGKFIPASPIVLSKGPWEQIPGGVTAAKGFRAAGMYAQLRAAGKKPDLALIVCDTDAVSAGTFTKNVVAAAPVIYCKKTLADSSTARAILINAGQANAATGDAGYQDTLECVAAVAKHCGVPEGAVLIESTGVIGRRIKKDALIEAVPKLVGSLSASVASADAAAVAITTTDLVSKSVAIETKIGGTTVRLGGIAKGSGMIHPNMATMLGVVTCDVDVTAEVWRPMVITAVNRSFNQITVDGDSSTNDTLLALASGAAGGPKISDINSEEARQLQAALDAVLQGLAKSIASDGEGATCLVEVTVTGASDEAAAATVARSVAASSLTKAAIYGRDPNWGRIACATGYAGVPFDPLCLQIYLGDFHLMEKGQPLEFDSNGASAYLKKAGEVHGTVSINICIGHGPGQSQAWGCDLSYDYVKINAEYTT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FHI1A_HUMAN
Sequence: MMSSVSTESKLQQAVSLQGVDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDEASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLKMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSILELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFPEAFSESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPDPEMFLQSLTEEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYDDLEVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQEASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC
What is the function of this protein?
Probable component of the FTS/Hook/FHIP complex (FHF complex) (PubMed:32073997).  FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997).
What are the official names of this protein?
FHF complex subunit HOOK-interacting protein 1A, FHIP1A, FTS- and Hook-interacting protein like, FHIP-L.
What is the protein family that this protein belongs to?
Belongs to the FHIP family.
Protein: SIG14_HUMAN
Sequence: MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLVLTLIRGALMGAGFLLTYGLTWIYYTRCGGPQQSRAERPG
What is the function of this protein?
Putative adhesion molecule.  Sialic acid-binding paired receptor which may activate associated receptors.
What are the official names of this protein?
Sialic acid-binding Ig-like lectin 14, Siglec-14.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: FINC_XENLA
Sequence: MRRGALTGLLLVLCLSVVLRAAPSATSKKRRQAQQQQQQQVVQPQGTQDNHQKGCYDNGKYYQINQQWERTYLGNTLVCTCYGGGRGFNCESKPESEETCFDKYTGVSYRVGETYERPKDNMIWDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPVAERCYDNTAGTSYVVGQTWEKPYQGWMMVDCTCLGEGNGRITCSSKNRCNDQDTKTSYRIGDTWSKTDTRGNLLQCICTGNGRGEWKCERHSSAQATGTGSNPITNIQTALYQPDSQLEPYGHCVTDNGVLYSLGMRWLRTQGSKQMLCTCLGNGVSCEETVATITFGGNANGEPCAIPFTHDGKTYYSCTSEGRQDGKLWCATTSNYDSDKKYSFCTEQLALVQTRGGNSNGALCNFPFLYNNLNYTDSTSEGRQDSMKWCGTTANYDADQKFGFCPMAAHEEICTTNEGVMYRVGDQWDKQHDQGHMMRCTCVGNGRGEWSCVAYSQLKDQCIVDGLTYNVNSSFTKLHEEGHMMNCTCFGQGRGRWKCDAIDQCQDTETRQFYQIGDSWEKHLQGVQYQCYCYGKGIGEWHCQPLSTSQAGTGPVQVIITESANFPTSHPIQWNAPQASHIKNYILRWKPKLKAGPWKQATIPGHLNSYTISGLKPGILYEGQLISILQYGNREVTTFDFTTTTTIHRHSQTESGETTPLPPLVSISESVTEITASSFLVSWVSASDTVSGFRVEYELSEDGDEKRYLELPNTATSVNIPDLLPGRRYNVNVYQITEEGEKSLILSTTQTTAPDAPPEHNVENVDDTSIMIKWNKPQAPITGYRVVYSPSVEGSSTELNLPSTANSVTLTELLPGIEYNITIYAVEDSLESVPVFIQQGTTGTPQTVIVPSPTDLQLVEVTDVKIIIMWTSPQSEVSGYRVVVKPVSPAGRDVQNLPVNRNTFAEVVNLQPGRTYSFEVYAVNRGQESEPLVGEFATKLDAPTDLQFTDVTESTVVIIWIPPQAKIGRYLLSVGQTRGGQPSQFPINPSVTNHKLDNLLPGTEYTVSLVALKGNQQSASASGVFSTLEPVGSIPHYNTEVTETTIVVTWTPVPRIGFKLDVRPSQGGEAPREVISESGSIVISGLTPGVEYTYSISVLTDGVEKDIPITKTVVTPLSPPTNLRLQPSRDSATLTVYWDRSISPGITGYRISTTPTPMQVGNSLEEEVGPSQTYCVFENLSPGVEYNVSVYAVKEEEESAPLSQMFLQEIPQLTDIKYDDVTDTSIDLRWTPLNSSNIIGYRITVVAAGESVPIYEEFVGPTDGYYKVSGLEPGIDYEISLITLINGGESAPTTIIQHTAVPPPTNLRFTNIGPDNIRVTWSPPTSIELSSYLVRYSPVKKPDDVTELSLSPSTNMVVLSNLLPFTEYLVSVHSVYEERESSSLNGVAKTHLDSPTGIAFSEITPNSFTVHWIAPRGPITGYRIRYQLESGAGRPKEERVPPSRNSITLTHLIPGSEYLVSIIAINGQQESLPLAGQQATVSDVPTDLEVTSSSPNTLTISWEAPAVSVRYYRITYSQTGGHGPEKEFTVPGTSNTATIRGLNPGVSYTITVYAVTGRGDSPASSKPLTIIHKTDVDQPIDMAVTDIQDHSIHVKWSPPPGPVTGYRVTSVPKSGQGETFSQVISPDQTEVTIVGLQPAVEYVVSIYSQGENGESEPLVETAVTNIDNPKGLTFTDVGVDSIRLAWEVPDGQVTRYRVTYSSPEDGVKELFPAPEGDDDTAELHGLRPGTEYTVSIVALHDDMESKPLIGIQSTAIPAPTNLQFSQVTPSGFSLSWHAPTVHLTGYLVRVNPKEKTGPTKEVRLSPGVAATTVTGLMVATKYEVNVYALKDSLTSQPLQGLISTLDNVSPPRRPRIQDVTETTVTLSWRTKTETITGFQIDAIPADGQNPIRRTVDADLRTFTITGLQPGTDYKIYLYTLNDNARSSPVTVDVTTAVDSPSNLRFLTTTSNSLLFTWQPPRARITGYIIRYEKAGGLIKEHLPRLPAGTTESTLTNLEPGTEYIIYIIAVRNNMKSEPLVGRKRTDELPRLVTLPHPGQGPEILDVPTDEENTPHITQTKLDNGNGIQLPGSNGQQPSSDHEGQLIEEHGFRSPLAPTTAVPVRPGKFAPGRYPQERVDIELDTFPVQHGDFDGPYPHGLGPQLNDSGVQEVASHTTISWRPELETTEYIISCHPIDHEEAPLQFRVPGTSSSATLNGLTRGATYNIVVEAQKGTDKHKVLEKRVTVGSPGSPEGVLQPVEDTCYDTFSGAHYSVGQEWERMSESGFRLWCKCLGYGSGHFRCDSSKWCHDNGVNHRIGEKWDRRGENGQMMSCTCLGNGKGEFKCEPPEATCYDEGKMYNVGEQWQKEYLGAICSCTCYGGQQGWRCDNCRRPGAVSPDGTAGQTVSQFTQRYQQNYNLNCPIECYLPLGLQADTQHSQQTQK
What is the function of this protein?
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin.  Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (By similarity).  Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.  Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).
What are the official names of this protein?
Fibronectin, FN.
Protein: APT_CLOK5
Sequence: MNLQDNIRIVEGFPKKGISFKDITTLIRDKDAFKYAVDKIAGYLKDKNIDVVVGPEARGFLFGAPIAYTLGAGFVPVRKQGKLPYDTLSIKYDLEYGSDVLQIHKDAINKGDRVALVDDLLATGGTTSSVVKLIEQAGGEIVTIDFVIELTDLKGREKLKGYDVLSLIKYDI
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPM_PSEPG
Sequence: MSSTLIVQLDMRTLCQEADVTADCVIEIVEHGIVEPSGRTPEDWLFDDQAPLLTRRAAKLHQELELEWEGVALALELLQEVQQLRSENSMLRQRLGRFTQM
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: SURE_MARMM
Sequence: MIPENPRILLTNDDGIRAHGLKVLEKIARQLSDDVWIVAPAEEQSGAGRSLSLHDPLRVRRFDERRMSVSGTPTDCVLMGIQDLIPGKQPDLVLSGVNRGQNIAEDVTFSGTVAGAMQGMQLGIPSVALSQAYGFGKDDPIQWETAEMYGAPILRRLFDLKWPDDVLININFPDRKPGDVEEVEVTRQGRRDQHILHAEHRVDPRGMDYYWLAFKGLLSNPPDGVDLRAIYDGKISVTPLHMDLTHGETLGNLKRMLGGVPPKS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAFA2_MOUSE
Sequence: MNKRYLQKATQGKLLIIIFIVTLWGKAVSSANHHKAHHVRTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRVTH
What is the function of this protein?
Has a role as neurotrophic factor involved in neuronal survival and neurobiological functions.
What are the official names of this protein?
Chemokine-like protein TAFA-2.
What is the protein family that this protein belongs to?
Belongs to the TAFA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COAT_SSADV
Sequence: MAPKRSRRSNRRAGSRAAATSLVYDTCYATLTERATTSFQRQSFPTLKGMGDRAFQVVSFTIQGVSAAPLMYNARLYNPGDTDSVHATGVQLMGTVPRTVRLTPRVGQNNWFFGNTEEAETILAIDGLVSAKGANAPSNTVVVTGCFRLAPSELQSQ
What are the official names of this protein?
Coat protein, Capsid protein.
What are the subcellular locations of this protein?
Virion.
Protein: Y601_MYCBO
Sequence: MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAALTTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMAVLVSQASRQ
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Mb0601.
Protein: TRPC_METTH
Sequence: MLRDIIRSKKLEVKELMKKTPLSILRDDITVMDEPVSFPAAVGGGKVSLICEYKRASPSMGRISERGLEEMMEVYQDLADAVSIVTDGKYFKGSLDLLSGATDYGKPLLMKDFLVDEYKIYQARASGASSVLLITGVFPDLEAGIQKCRELSMEPLVECHTSLDIFRALEAGAEIIGVNNRDLETFEVDLERTHALAPLVPDELILVSESGVRGPEDAEILAGYGADALLIGTAPMSAQNPRELLEEIVDAVSQCRDRRRRYTGDEFFEQFA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: DEF_ECO57
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: LEPA_GRAFK
Sequence: MKNIRNFCIIAHIDHGKSTLADRLLDFTGAVTEREKQEQLLDSMDLERERGITIKSHAIQMDYVHEGEEFVLNLIDTPGHVDFSYEVSRSIAACEGALLVVDAAQSIQAQTISNLYLALENDLEIIPVLNKVDLPSANPEEVTDDIVDLLGCDPSEVIPASAKTGLGIKEILDAIINRVPAPSGKVDAPLRALIFDSVYNPFRGVETYFRVINGSIKKGEKIKFVATGKTYDADEVGTLRLKQFPRKEIKTGDVGYLITGIKDAREVKVGDTITSAVNPTTEAVAGFEDVKPMVFAGIYPVDTEDYEDLRSSMEKLQLNDASLVFLPESSAALGFGFRCGFLGMLHLEIIQERLEREFDMTVITTVPNVSYHAYTNKNPDDVILVNNPSDLPEPSSLNRVEEPFIKATIITKADYVGNVMGLCIEKRGEITNQTYLTTERVELTFDMPLAEIVFDFYDRLKTVSRGYASFDYTPIGLRESKLVKVDVLLNANIVDALSALLHVDNAYDIGKKMCEKLKELIPRQQFDIPIQAAIGAKIIARETVKALRKDVTAKCYGGDISRKRKLLEKQKKGKKRMRQVGNVEIPQEAFMAVLKLND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL4_PSEMY
Sequence: MQLNVNGAQAIEVSDATFGGEFNETLVHQAVVAYMAGGRQGTKGQKSRSDVSGGGKRPWRQKGTGRARAGTTRGPIWRGGGVTFAASTRNHDQKLNKKMYRAALRSILAELVRTDRLVVVEDFAVEAPKTKALLSKLNGLGLNDVLIVSDAVDQNLYLAARNLPHVDVRDVQGSDPVSLIAYEKVLVTVSAVKKFEELLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: KEFF_KLEP3
Sequence: MILIIYAHPYPQHSHANKRMLEQAGTLEGVEIRSLYQLYPDFNIDVAAEQAALARADLVIWQHPMQWYSVPPLLKLWMDKVLAHGWAYGHNGIALRGKPLMWAVTTGGGESHFDIGSFPGFPVLAQPLQATALYCGMKWLPPFAMHCTFICDDETLQAQARHYRQRLIDWQEAHQNG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TIG_HAEI8
Sequence: MSLNIETTQGLERRVAITVPTEIVSKAVREEFKRAAKNVRVDGFRKGHVPAHIIEQRFGASIRQDVLNDLLPRHFFDAVIAEKINIAGRPTFAIETFEEGKDLVFTATFEVYPEVKLQGLENIKVEKPTVEITEADIDKMIDVLRKQQATWAESQDVVKADDRVTIDFVGSVDGEEFEGGKATDFVLFMGQGRMIPGFEEGIVGHKAGEQFDIDVTFPAEYHAENLKGKAAKFAITLKKIENMVLPELTDEFVAKFGPNTKSVADLRAEIRKNMERELKNALVSRVKQQVINGLIEQNPIDVPASAVEEEINVLRNQAAQRFGGNAQQTAQLPRELFEAEATRRVQVGLLFSEVIKSNELKADEERAKAMIADIASAYEQPAEVVEYYSKNEELMNNIRNVVLEEQAVDAVLAKAQVTEKVSSFDEIMNPQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PB2_I83A1
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMNDAGSDRVMISPLAVTWWNRNGPVASTVHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQNCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKLKVHEGFEEFTMVGKRATAILRKATRRLIQLIVSGRDEQSIVEAIVVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSMRGVRVSKMGVDEYSNAERVVVSIDRFLRVRDQRGNVLLSPEEVNETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: RL28_PARUW
Sequence: MSKVCQVTGRKPTRGYKYAIRGIAKKKKGIGLKVTGKTKRRFQPNLFKKRIWFAEENRFITLKLSTAALRTIDRLGVFAVVRKMRANGQSV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: BABA2_BRAFL
Sequence: MSSGQSVLKQLHPLIRPYAETVLRKGNVGVCMGNLRISDVKSGRPTLTQTKEPCGDRFKIYIPFAGDSLKWEVIFDSCQPSNPPDFIFLGENGNFDPDIEKLENLTHWDPKNPESLVLAIEDLMREYRCYQKQLIEGYSRLQFEYSSLQGMEACDDVEVHMGNRLPGTLDSPVNFLIRLPIDLSPIPQYLVKDDPGEDLAVLLAKFHNSEGSRVTPQLFLSPKVEHALGDNTALRIPRFPTGGCLMDYVPQVQDFLQKQIDHIVEGYQRRREYVAAFISRFGGSVLEYDAESFTKLSLVLEWNEFFFVLHIELPSRFPQDMPVFTFQSCYHLSKTNGEPYVSVQKSYPYSPRWTGEEMAHRAKLFILDFIPQFKKVSVSSNKL
What is the function of this protein?
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).  The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.  In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer.  Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates.  Within the BRISC complex, acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity.  The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.  The BRISC complex plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression.  Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination.  May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins.  May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.  May regulate TNF-alpha signaling through its interactions with TNFRSF1A; however these effects may be indirect.
What are the official names of this protein?
BRISC and BRCA1-A complex member 2, BRCA1-A complex subunit BRE, BRCA1/BRCA2-containing complex subunit 45, Brain and reproductive organ-expressed protein.
What is the protein family that this protein belongs to?
Belongs to the BABAM2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: GLO2_THIDA
Sequence: MLTLIPLPAFEDNYIWVWHDAKYAVAVDPGDPAVLSTYLDSRGLALAAVLVTHHHRDHTGGNTWLRQRYNCAIYAPDNPRIPAVSHVVRGGDSVAVPELGLALAVLATPGHTLDHVSYVGNGHLFCGDTLFGCGCGKLFEGDAAMMSASLDALAALPPTTRVCCAHEYTLSNIDFAKTIDGANPALLERERIDRAARAQNRPTLPSTLALERTTNPFLRFHDADMRAFAVGELGSPDPGPATVFGAIRAAKDRWDG
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CAID_SALSV
Sequence: MSESLHLTRNGPILEITLDRPKANAIDAKTSFAMGEAFLNFRDDPELRVAIITGGGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCAENASFALPEAKLGIVPDSGGVLRLPKLLPPAIVNEMVMTGRRMSAEEALRWGVVNRVVSQSELMESARELAQQLVNSAPLAIAALKEIYRATSEMPVEEGYRYIRSGVLKHYPSVLHSEDALEGPQAFAEKRDPVWKGR
What is the function of this protein?
Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
What are the official names of this protein?
Carnitinyl-CoA dehydratase, Crotonobetainyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: GAUT4_ARATH
Sequence: MMVKLRNLVLFFMLLTVVAHILLYTDPAASFKTPFSKRDFLEDVTALTFNSDENRLNLLPRESPAVLRGGLVGAVYSDKNSRRLDQLSARVLSATDDDTHSHTDISIKQVTHDAASDSHINRENMHVQLTQQTSEKVDEQPEPNAFGAKKDTGNVLMPDAQVRHLKDQLIRAKVYLSLPSAKANAHFVRELRLRIKEVQRALADASKDSDLPKTAIEKLKAMEQTLAKGKQIQDDCSTVVKKLRAMLHSADEQLRVHKKQTMFLTQLTAKTIPKGLHCLPLRLTTDYYALNSSEQQFPNQEKLEDTQLYHYALFSDNVLATSVVVNSTITNAKHPLKHVFHIVTDRLNYAAMRMWFLDNPPGKATIQVQNVEEFTWLNSSYSPVLKQLSSRSMIDYYFRAHHTNSDTNLKFRNPKYLSILNHLRFYLPEIFPKLSKVLFLDDDIVVQKDLSGLWSVDLKGNVNGAVETCGESFHRFDRYLNFSNPLISKNFDPRACGWAYGMNVFDLDEWKRQNITEVYHRWQDLNQDRELWKLGTLPPGLITFWRRTYPLDRKWHILGLGYNPSVNQRDIERAAVIHYNGNLKPWLEIGIPRYRGFWSKHVDYEHVYLRECNINP
What is the function of this protein?
May be involved in pectin and/or xylans biosynthesis in cell walls.
What are the official names of this protein?
Probable galacturonosyltransferase 4, Like glycosyl transferase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: ALGA_PSEFL
Sequence: MIPVILSGGSGSRLWPLSRKQFPKQFLALTGEHTLFQQTLERLVFEGMDTPIVVCNKDHRFIVNEQLANRKLECQRILMEPFGRNTAPAVALTAMMLVNEGRDELMLVLPADHVIDDQKALQRALALATVAAERGEMVLFGVPATRPETGYGYIKSTNDSLLPEGVSRVQQFVEKPDEKRAVEFVKSGGYFWNSGMFLFRASRFLEELKKHDPDIYDTCVLTLERSEQTADTVTLDDATFACCPDNSIDYAVMEKTQRACVVPLSAGWSDVGCWASLWAVNDKDIHGNVSKGDVVIQDSRNCMIHGNGKLVSVIGLDNIVVVETKDAMMIAHKDKVQGVKQMVSTLNDQGRSETQNHCEVYRPWGSYDSVDMGGRFQVKHISVKPGACLSLQMHHHRAEHWIVVSGTAEVTCDENVFLLTENQSTYIPIASVHRLRNPGKIPLEIIEVQSGSYLGEDDIERFEDIYGRSTPVERGVSVKTIAQ
What is the function of this protein?
Produces a precursor for alginate polymerization.  The alginate layer provides a protective barrier against host immune defenses and antibiotics.
What are the official names of this protein?
Alginate biosynthesis protein AlgA.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 2 family.
Protein: RBFA_STUS1
Sequence: MAKEFSRTQRIGDQMQRELALLIQREIKDPRLGLITITAVDVSRDLSHAKIFITIMGQDDDQEAIKGNLRILNDAAGFLRMQLGKSMKLRTVPQLHFNYDASIRRGVELSSLIERAVAEDRKHSDERGE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
Protein: TRUD_YERPA
Sequence: MDMENLTWLHGKPTASGILKANPEDFVVVEDLGFEPDGEGEHLLVRIRKNGCNTQFVADYLARFAKLHPRLVSYAGLKDRHAVTEQWFCLHLPGKEAPDLATFELEGCEVLEAVRHKRKLRIGSLKGNAFTLVLRHITDRQDVEQRLQQIAAQGVPNYFGSQRFGRGGNNLVQARLWANNEIRVKERSKRSFYLSASRSAMFNLISSYRLAQQLSTTVLEGDALQLSGRGSWFVAQADELAALQQRVTAGELNITAPLPGDSELGTHGEALAFEQACLAEQTELLSLIKRERVEGSRRAVLLKPQNMISNWWDDVTLELSFWLPAGSFATSVVREIMNQDRADDTDIIE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.