PharMolix/UniProtQA huggingface dataset:
Protein: GUF1_NAEGR
Sequence: MLSSSLSNDNENNRRNYVSKSNKNGLVFECSELKEELKRLSIMNRNNIYSNVWMRNIGFSKQQQVRNYSVLPTNAKKIKEHNKSALDLSGFTPEYIRNFCIIAHIDHGKSTLADYLLKETNTITAELLKDNAQFLDRLQVERERGITVKAQSCAMFYEYNGKKYLLNLIDTPGHVDFSYEVSRSMGACDGALLLVDSGQGVQAQTLANYFLALEENLEIIPIMTKIDQQTAQPELVEEDMTGILGVEKDEIIKVSAKTGLNCQKIIPAVIEKIPAPEPPKVSEGETPGALKSLIFDSWYDEYFGVVSLVYIAQGSVEVGDFIYSHANVKNSAKPTKYQVTKLGIMNPDQVPTDKLYQGQVGYLICGMKSTKEAQIGDTLYIWDSKIEPLPGFKQAKPMVYAGIYPLNTAEFDKLRDVIDKLLLTDRSVTIEKETSAALGTGFRCGFLGLLHMDVFKQRLAQEFTIETIITAPTVTYKIVTKNTGKKTSFNTVEDEIIEYIDNPNDFPENPEAEVYEPMANCTIMTPREFVGDIITLCQERRGVQIHMEYFSAERVSMQYKIPLNEMIYDFFDKLKSMTKGYATLDYEEAGFERSDVVKLTVMLNKDPVDALSYIVHESKAYFKARDVVQRLKKLISRQLFEVNIQCAVGLKIIASEKLKAFRKNVTAKCYGGDITRKRKLLEKQKEGKKKMKQLGSVSVPQDAFTVLFSEGEIEDADLSD
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: LEC2_LATOC
Sequence: ETSYTLNEVVPLKEFVPEWVRIGFSATTGAEFAAHEVLSWYFNSELSVTSSSN
What are the official names of this protein?
Mannose/glucose-specific lectin alpha 2 chain, Lol II.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: PRP4_MOUSE
Sequence: MASSRASSTTTKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
What are the official names of this protein?
U4/U6 small nuclear ribonucleoprotein Prp4, U4/U6 snRNP 60 kDa protein, WD splicing factor Prp4.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: T23O_CUPNH
Sequence: MSEFKGCPFSGAASEAGTKAQGEGWHGAQMDFAKDMSYGDYLGLDQILSAQHPLSPDHNEMLFIVQHQTTELWMKLMLHELRAARESVKADSLPPAFKMLTRVSRIMDQLVQAWNVLATMTPPEYSAMRPYLGMSSGFQSFQYREIEFILGNKNAAMLKPHAHRPEHLALVETALKTPSLYDEAIRLMARRGFAVDADCVERDWTQPTAYNASVEAAWLEVYRNPSAHWELYELGEKFVDLEDSFRQWRFRHVTTVERVIGFKRGTGGTEGVSYLRKMLDVVLFPELWKLRTDL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: MUTL_LACLS
Sequence: MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKITVSVEEAGLRLIEVTDNGLGLEKEDVALALRRHATSKIKDSADLFRIRTLGFRGEALPSIASVSQMTIETSNAQEEAGTKLIAKGGTIETLEPLAKRLGTKISVANLFYNTPARLKYIKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMREINGSDLDFELTGYVSLPELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAVLSIKIDPKLADVNVHPTKQEVRLSKERELMTLISKAIDEALSEGVLIPEALENLQGRVKEKETVSVQTELPLQNNPLYYDNVRQDFFVREEAIFEINKNDNSDSLTEQNSTDYTVNQPETGSVSEKITDRTVESSNEFTDRTPKNSVSNFGVDFDNIEKLSQQSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHAAQERIKYEYWKDKIGEVSMEQQILLAPYLFTLPKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSINEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLRELATCKNPYSCAHGRPTIVHFSGDDIQKMFRRIQETHRSKAASWKDFE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: TPC13_XENTR
Sequence: MDVNQPKQEHLLALKVMRLTKPTLFTNIPVTCEERDLPGDLFSTLMKDDPSTVKGAETLMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDIQVKADLQTSSQRLNLSASTAVVSELKPDSCIDDVIHHEVKEIGTHILVCAVSYTTQTGEKMYFRKFFKFQVLKPLDVKTKFYNAETDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVSELNTVITNGDGCSTFGTKTYLQPLDTRQYLYCLKPKPEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSIETIPDTVRLEEPFDITCKITNCSSERTMDLVLEMCNTNAIHWCGVSGRQLGKLHPSSSLHLTLALLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSKLQAES
What are the official names of this protein?
Trafficking protein particle complex subunit 13.
What is the protein family that this protein belongs to?
Belongs to the TRAPPC13 family.
Protein: SPAN1_BPP21
Sequence: MNRVTAIISALVICIIVCLSWAVNHYRDNAITYKAQRDKNARELTLANRVITDIQMRQRDVAALDAKYTKELADAKAENDALRDDVAAGRRRLHIKAVCQSVREATTASGVDNAASPRLADTAERDYFTLRERLITMQKQLEGTQKYINEQCR
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit (PubMed:22904283).  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin have permeabilized the inner membrane and degraded the host peptidoglycans.  Host outer membrane disruption is due to local fusion between the inner and outer membrane performed by the spanin complex (By similarity).
What are the official names of this protein?
Spanin, inner membrane subunit, i-spanin, Lysis protein Rz.
What is the protein family that this protein belongs to?
Belongs to the Lambdavirus i-spanin family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: Y1790_LISMC
Sequence: MDNGIFIVATIFIVNILYVTIYTVRLLLTMKGYRYLAALSSVFEMIIYVVALSLVLDNLNNIANVLAYAIGFGVGIIVGMKIEERIALGYITVNVITKEYNLDLPNQIRDLGYGVTSWLASGRDGERMMLEILTQRKNERKLYKHIIEIDNGAFIVSSEPKQIHGGFWVKQVRK
What are the official names of this protein?
UPF0316 protein Lm4b_01790.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNZ_LACAC
Sequence: MELQFLGTGAGQPSKQRNVSSVALKLLDELNEIWLFDVGEATQHQILRTNIRLRKVTKIFISHNHGDHIFGLPGLLSTRSFQGDVGPLTIYGPAGIEDFVKISLKVSRTKISYPIHYVELSEPGLICEDRGFKVYTDRLDHRIPSFGFRVVEDSHPGELLIDKLAEYNIPNGPILGKLKNGEQVALADGTILDGKDFLGPEKPGRIITIIYDTRSTSSIAHLAKDADVLVHESTFAGDESKMAHNYYHSTSVQAAKIARQENVKQLCLNHISARYMGAKAKKLENQAKKVFPNTILVNDFDRVNIPMKGSKK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RSMA_ACIET
Sequence: MKHIPRKRFGQHFLSDSGIIDAIVRAIAPEPGQPMVEIGPGLAALTQPLVERLGRLTVVELDRDLAARLRQHGQLDVIESDVLKVDFAQVAQALNAPKIRVVGNLPYNISTPILFHLLAHVRVIADQHFMLQKEVIDRMVAAPATSAYGRLSVMLQWRYAMENVLFVPPESFDPPPRVDSAVVRMVPHEAPEALSMPVLEELVQVAFSQRRKLLRHTLGRWLEARQFAGTFDTQRRAEEVPVSEYVALAQKCS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUPK_RHOCA
Sequence: MSAALGIVLRPEGQRLAVSLTPPDPLPVAALLLGKPPGQVAELLPRLFNLCGAAQGHAARLALGLPAEAAPARREILRDHLAKLCLIWPKLLGLAPQPLPEHWAEGGAALQHWLWGGAKPADLWPFLTSGQGVAPLLATLGHAFAPGEAVAVLPPLSDPMALTAQENSPAGRVADDPLMRQAEARFGRGPFWRALGRIVDLHAFALAPPAAATPRPGLALVAAARGTYALSARAEAGMVTALSRVTPTDHLLAPCGALALSLASLPAAKAGLAALVIDILDPCVAVSVQELAHA
What are the official names of this protein?
Hydrogenase expression/formation protein HupK.
What is the protein family that this protein belongs to?
Belongs to the HupK family.
Protein: YVC1_CANAL
Sequence: MSELDLEENNPLLPPSQINDENYEGSIFGEDARFCPNSRQVFRICSNLKLLIDKIIPICFKEDEITSSNSAILSDPVIDLVYQAAGGKGDGKEGTSSYKYRGSLVFCLLKVCDWYWQQAEFELSDNELYSLRALTAQTIAAIIIEREKRDKYLFLNMLCHRYTICVNGVDATPVSALEMAVDMHSTIVIGSSGYQRCIKWLWRGWIIQSSTDPHSYVLYKGAASQSFRTHFDPARIKTPLYQNILEIFLSIIYLIIFTIVVNTHSTLTGDIDFFETVLYLFTVGYILDEFIKFYHVGWNYLGFWNAFNDTMYCILTVAVCFRIASVNSHGATRIKYDEISFRVLACASPLMWSRLLLFLDAYKFVGAMIVVLKTMMKESILFFFLLFVVIVGFLQGFIGLDSSDGKNEATQRILISLVKAVIGGSSFEDMGNLVPPYASVLYYFYQFMLTVILMNILIALYSTAYAAIVENATDEYFALVAHKTLRYIRAPDQNLYVPPFNLIELLITPIGWFVSTSTWKNINYYVMLVIYSPLLAYITSDELSNARRIQYNRFKGVPDDANEIDTEWDLTDGYDEDSPGDGDDCWDRIRERNSEITEELRIQREGERQDPEFMINTHQFSEKIDKIVKPVGQASKVGVNWQIYEVIEKIDKLTNLLEVVVAENKELKKRLENKA
What is the function of this protein?
Vacuolar calcium channel involved in the release of calcium ions from the vacuole in response to hyperosmotic or alkaline stress.  Required for activation of CAP1-related transcription of oxidative stress response (OSR) genes, but also for maintaining the stability of both the mitochondria and the vacuole in a potassium- and calcium-dependent manner.  Contributes to pathogenicity.  Plays a key role in hyphal polarized growth and re-orientation to host-signals through its contribution to the localization of the Spitzenkoerper to the hyphal tips.
What are the official names of this protein?
Calcium channel YVC1, Vacuolar transiant receptor potential (TPR) channel YVC1, Yeast vacuolar conductance protein 1.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: GLOB9_CAEBR
Sequence: MRRMAKYDRSYSMQDAHGPNGLARRGTQRGCSRSKSTRRGNLGTIASLTFSQKQALNLSWRLLKPQASACFRKIFLELEIASPKVKQIFYKAALVDAFNKDDDNTATLEVHIKLTTKFFDELLATLDDENEFVAKIRGIGSAHAILAKGSNFSSDIWERLGEIAMERVCSHEVVTKTREASRAWRTLIAILIDELRGGFEGELRQHRKSSSTDQIEMGKVEDEEELHSKLQQLRMDYNQTLPYT
What are the official names of this protein?
Globin-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS12_BARHE
Sequence: MPTVNQLIRKPRITPIKRNKVPALQSNPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGLLDTQGVKNRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL18_SULAC
Sequence: MTQGPNYRIKFRRRREGKTDYYTRYTYVINNAIRFVPRLTNKYVIVSVSKFDQKGDIMIAYAHSIELVKKYGWKGDTNNTPAAYLTGYLAGLRAVKSGVKAAVSDIGLFVPVKGGRIFAVIKGAIDAGLKVPVGDLGKLKDRVNGSHISAYAQKLKNENQELYNKLFSSYIQRGLDPVLLPQHFEEVLNKIKENGGK
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: YNFB_ECO57
Sequence: MKITLSKRIDLLAFLLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTGNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: RL25_NEIG2
Sequence: MTYEIQASVREAQGTGASRRLRREGQIPGILYGEGQEPVAIAVDHKTVFYALEKESFHTALIKLSLNGETKDVIVRDFQMHPFRREVQHIDFQAVKADQLVRIRVPLHIVNAENSQAVKLQGGRVSLLNTAVEVLALPANIPAFLDLDCAEVVAGDILHLSDIKLPEGVESVSLKRNENLAVATVTGKKR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: Y3401_YERPS
Sequence: MKRTKNINQETFRKSWRSYRLAPVALAVSAVFMLAGCEKTDETVSLYQNADDCSQANPSQSAECTTAYNTALQEAVKTAPKYATREDCVAEFGESQCTQAPAQAGMVPTSSSETTAAAPQQSGSMWMPLMAGYMMGRMMGGGASQPLFTSKAPNSPANGKFVDASGKNFGAATTGRTMTVPKTALAPKPAVTKTITRGGFGESVAKQSSMQRSAATSSKTTTRSMGG
What are the official names of this protein?
UPF0441 protein YPTB3401.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: THI41_SORBI
Sequence: MATTAASSLLKSSFAGSRLPSATRAPSSVVVSTGGAPRTAAISASISSSNPPYDLTSFKFSPIKESIVSREMTRRYMTDMITHADTDVVIVGAGSAGLSCAYELSKDPTVRVAIVEQSVSPGGGAWLGGQLFSAMVVRKPAHLFLDELGVAYDEAADDYVVVKHAALFTSTVMSAVLARPNVKLFNAVAVEDLIVKGGRVGGVVTNWALVSMNHDTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKRLQDIGMIAAVPGMKALDMNAAEDAIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKALGRPNAVDGTIPKVSPALREEFVIASKDDEVVDA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase 1, chloroplastic, Thiazole biosynthetic enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIC60_AJECG
Sequence: MLRTSIASSRPLLPSSVCPKAPAQWLCTSRARRVNTATRRYHALARKSNAGRRCSLTPNTATTSQFFQKAASSTSTKPPGPSDADVRSPASPSSRSSLRPESIPKPPQSPPVQGQTSPGSEVLPPDHESSTPPPPPGPKSSRLRKLLYLFLTAGLAYAGGVWYSLRSDNFYDFFTEYIPYGEEAVLYLEERDFRNRFPHVTKQINRRVTVPKDEGAQVTIPSGSGLSWKVAEEQQEATDMTKKGRRMGTAHANEPTKDIKVAEKAKEEVKSKSAAKKEDVAANIPIQEALEPQPAKTEEKNLEAPRQPAVPAVTAIERLVQDKADEPVVQDLVKVFNDVISVISADESASKFAGPIAKAKEELQRIGDRIVALKKDAQESAQEEIRNAHAAFDKSAAELIRRIDEVRTQDAAEFREEFESEREKIARSYQEKVNTELQRAHEVAEQRLRNELVEQAIELNRKFLSDVKTLVENEREGRLSKLAELSANVAELERLTAGWSDVVDINLKTQQLQVAVDAVRTTLENSDVPRPFVRELAAVKELASNDEVVAAAIASISPAAYQRGIPSAAQLVDRFRRVASEVRKARLLPENAGITSHAASLVLSKVMLKKQGLPTSDDVESILTRTENFLEEGNFDEAAREMNSLQGWAKLLSKDWLADVRRVLEVKQALEIIETEARLRCLQVE
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: LPXD_POLNS
Sequence: MPTAIELAEQFQASLVGEAPHGFTGLAPLERAQSNQISFLSNLLYRQQASESAAGALIVSQSDLDFLQANPGANSVKRVYFVAKNPYTTFARMAQYFAKANDPIYASGIHPSAVIDSTAIVPPSCHIGPFVQIGAGVKLGERVSILGNSSIAKDSVIASDTLIYPSVSIYHNTQIGERCIIHSGAVIGADGFGFAPDFSATGGEWVKIPQTGRVVISNDVEIGASTTIDRGAMSDTVIGAGTKIDNQVQIAHNVIVGSCCVIAGCAAISGSTKIGNFCIIGGAANFAGHLTIADRTTVSGNTSIIRSITEPGQHFTGVYPSMLHGAWEKNAAILRGLDKIRQRLRLLDKNKNSGS
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RPOB_GRATL
Sequence: MRLLMSQEIMFKYIFPDLAAIQKESFKSFLLEGLSEVLDSFPIIVDPTGKLELQFFGKDYKLKFPRYSVRKAKSRDKTYSAQIYIPAKLTRRDIEVIKENISTSKDLSYFFNSQDINKKYRKRPVFIGDLPLMTNRGTFVISGTERIIINQIVRSPGVYYKKELDKNNKQIYSCSIISNRGSWLKFEIDSKAQIWAKIDKNHKVSAYIFLRSIGLNNEDIRKRLTKYNYLINSSLTYYKKEFSKDVNNVDIEKITEEEALVIVYSKLRPNEPATLAVAKQMLYTRFFDPKRYDLGAVGRHKINQKLNLKVPTHFRVLSPEDILVSLDYLLNIKEQNIGTFDDIDHLGNRRVRSVGELLQNQVRIGLNRLERIIRERMIICDLDSLSLSNLVNPKPLMASVREFFSSSQLSQFMDQTNPLSELTHKRRISALGPGGLNKDRAGFAVRDLHPSHYGRICPIETPEGPNAGLIGSLSIYAKVNRYGFIETPCYKVTDGQVLKKDKLYYITADQEDYLRIAPADISLDVNDFIQDKIIAVRYKQEFITATISQVDYMAVSPIQFISAATSLIPFLEHDDANRALMGSNMQRQAVPLLFPEKSIVGTGLEAKIAKDSGMTIISRTNGTVSYVSGTKIGIQNKEGYTIHYRLKKYYRSNQDTCINQRPIVWPGENIRIGQTIADGASTDGGEIALGRNIIVAYMPWEGYNYEDAFLISERLVYEDLYTSIHIERYELECRQTKLGSEEITRDIPNVSEASIGLLDKNGIISIGSWVDAGDILVGKVTPKGESDQLPEGKLLRAIFGEKARDVRDTSLRLPNATKGRVVNVKIFKRQKGDELPPGTNEIIRVYVAQKRKIQVGDKMAGRHGNKGIISRILSLQDMPFLPDGTPVDIILNPLGVPSRMNVGQLFECLLGLAGEYSSKRFKIIPFDEMYGSEASRALVYNKLKQASSMNDKSWLFNALHPGKVMLVDGRTGEFFDNPVTVGKAYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRAQHGGQRLGEMEVWALEAFGAAYTLQELLTVKSDDMQGRNDALNAIVKGKPIPKPGTPESFKVLMRELQSLALDIAVHKLELLDNGNKASIEIDLMSDEQVSAI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL31_MYCSK
Sequence: MKTGIHPDYVETTVQCGCGNTFTTRSTKKTGNIVVEVCSQCHPFYTGKQKILDSGGRVARFEKRYGKRGANKAANTDSADK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: KTHY_LISMO
Sequence: MKAIFITLEGPDGSGKTTVGTLLNQKMTEAGIDFIKTREPGGSPISEKVRNIVLGIGNEEMDPKTEVLLIAGARRQHVVETIRPALAAGKSVLCDRFMDSSLAYQGAGRDMNMEQVLQVNLYAIEDTLPDRTYYLDVPAEVGLARIAANKGREVNRLDKEDITYHEKVQAGYEKVINMFPERFMRVDATKTPEEITETILADILRQLA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: BIOB_PORG3
Sequence: MIQTIENRLINGGEPTFEEALLLASSADKEALYETAHRITRHFMGDKFDTCSIINAKSGNCPEDCKWCAQSRHYATSIEKYGLLSATVCAEQAAYNRRQGIGRFSLVASGRTASMNEIRQMAESFRTIKQRTDIKCCASLGLLSEEKLQILFDNGVTTYHCNMETAPSFFPSLCSTHTQEEKLATIRAARRVGMRVCSGGIIGMGETMEQRIEFAFFLHSINVYSIPINILQPIPGTPLEKTPPLSEEEYLTTVALFRLINPRAFLRFSGGRAQLSPAVQRKAIYIGINAAITGDLLTTTGSKAAEDMQLARECGFQVTNDTDWEVSYDH
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SDHF2_KLULA
Sequence: MLRTVFNKPSVLKSGVNSITKQCRSLHANAYLLNKGNSNGAEGQDDDVTVRIRIPPIKRTGESLDKKRARLIYQSRKRGILETDLLLSRFAAKYLKEMTPEQLEEYDQLLNELDWDIYYWATENYSITPLPDRWKNSNILKQLQEFSKNKDREILSMPDLSKY
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TYSY_LISMH
Sequence: MKQYLDLEKYVLENGTQKGDRTGTGTISTFGYQMRFDLQEGFPIMTTKRVPFKLVVSELLWFLHGDTNIRYLLQHNNNIWNEWAFERFVKSDDYKGEDMTDFGLRAERDPAFKEVYQAEMEKFKTRILEDEAFANKYGELGNIYGKQWREWKTSQGETIDQLADLIEMIKTNPNSRRLIVSAWNPEDIPNMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAREVGLEVGEFIHTMGDAHLYNNHIEQVKEQLSRTPHKLPKLVLSDKPATIFDFDVADISLDGYNPDPAIKAPISV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1462_MYCTO
Sequence: MTAPGLTAAVEGIAHNKGELFASFDVDAFEVPHGRDEIWRFTPLRRLRGLHDGSARATGSATITVSERPGVYTQTVRRGDPRLGEGGVPTDRVAAQAFSSFNSATLVTVERDTQVVEPVGITVTGPGEGAVAYGHLQVRIEELGEAVVVIDHRGGGTYADNVEFVVDDAARLTAVWIADWADDTVHLSAHHARIGKDAVLRHVTVMLGGDVVRMSAGVRFCGAGGDAELLGLYFADDGQHLESRLLVDHAHPDCKSNVLYKGALQGDPASSLPDAHTVWVGDVLIRAQATGTDTFEVNRNLVLTDGARADSVPNLEIETGEIVGAGHASATGRFDDEQLFYLRSRGIPEAQARRLVVRGFFGEIIAKIAVPEVRERLTAAIEHELEITESTEKTTVS
What are the official names of this protein?
UPF0051 protein MT1509.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: Y2237_MYCTU
Sequence: MLLPAANVIMQLAVPGVGYGVLESPVDSGNVYKHPFKRARTTGTYLAVATIGTESDRALIRGAVDVAHRQVRSTASSPVSYNAFDPKLQLWVAACLYRYFVDQHEFLYGPLEDATADAVYQDAKRLGTTLQVPEGMWPPDRVAFDEYWKRSLDGLQIDAPVREHLRGVASVAFLPWPLRAVAGPFNLFATTGFLAPEFRAMMQLEWSQAQQRRFEWLLSVLRLADRLIPHRAWIFVYQLYLWDMRFRARHGRRIV
What are the official names of this protein?
Uncharacterized protein Rv2237.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.