PharMolix/UniProtQA huggingface dataset:
Protein: MURI_STAEQ
Sequence: MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIARCPYGPRPGEEVKKFTTELAQKLMEFDIKMLVIACNTATAVALDYLQNILPIPVIGVIEPGARTAIMTTKNQNVLVLGTEGTIKSEAYRTHIKKINPNVNVYSVACPGFVPLVEQMRYKDPTITNIVIHQTLKQWRNSDADTVILGCTHYPLLYQPIYEYFSGTKTVISSGLETAREVSALLTFSNEHASYTEHPQHRFFATGDTTHIKNIIDEWLNMKVEVKRITVNDS
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: FTSW_BUCBP
Sequence: MKTKLNIKLYDEKLLWCTLCLLLIGVTMVTSSSIPIAYRIYHDMLFFTKKQILYLVILFFIFKIFLDVPISFWQKNNKIILLISISTLLLVLIIGNSIHGSLRWITISYVSMQPSELSKLAMFCYLSNYLSQKNSEIVNNFGGFLKPIIIISFPLILLLVEPDLGTTIVILLTTLSLLFISGTKIQKFIPTILIIVVTTTVLIIKSPYRFERIMSFWNPWNDPFGKGYQLTQSLMALGRGNIFGMGLGHSIQKLEYLPEAHTDFIFAIIGEELGYIGACTILFMIFFISFRAFKIGKIALKNKIFFSGYFAFSIGLWLIFQTLINVGTTIGLLPTKGLTLPLISYGGSSLIIVSIAIIILIRIDFELRMKNIQAFYKTDI
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: PP361_ARATH
Sequence: MRDFVIVFGSSSAITNPHHHHRRCYATAPESNRKTKSNSSFTKLLPSLPQQHSPSPASVSATHSLSSHFSNVVRWIPDGSLEYYADFASKLAEDGRIEDVALIAETLAAESGANVARFASMVDYDLLSKGISSNLRQGKIESVVYTLKRIEKVGIAPLDLVDDSSVKLMRKQFRAMANSVQVEKAIDLMEILAGLGFKIKELVDPFDVVKSCVEISNPQLAIRYACLLPHTELLLCRIIHGFGKKGDMVSVMTAYEACKQILDTPNMYICRTMIDVCGLCGDYVKSRYIYEDLLKENIKPNIYVINSLMNVNSHDLGYTLKVYKNMQILDVTADMTSYNILLKTCCLAGRVDLAQDIYKEAKRMESSGLLKLDAFTYCTIIKVFADAKMWKWALKVKDDMKSVGVTPNTHTWSSLISACANAGLVEQANHLFEEMLASGCEPNSQCFNILLHACVEACQYDRAFRLFQSWKGSSVNESLYADDIVSKGRTSSPNILKNNGPGSLVNRNSNSPYIQASKRFCFKPTTATYNILLKACGTDYYRGKELMDEMKSLGLSPNQITWSTLIDMCGGSGDVEGAVRILRTMHSAGTRPDVVAYTTAIKICAENKCLKLAFSLFEEMRRYQIKPNWVTYNTLLKARSKYGSLLEVRQCLAIYQDMRNAGYKPNDHFLKELIEEWCEGVIQENGQSQDKISDQEGDNAGRPVSLLIEKVATHMQERTAGNLAIDLQGLTKIEARLVVLAVLRMIKEDYMRGDVVIDDVLIIIGTDEANTVSGKQEITVQEALVKLLRDELSLVVLPAGQRNIIQDAHCVDDADQENTKSFVSISSTRRPAILERLMVTKASLYQWLQRRK
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g02830, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPD53_HUMAN
Sequence: MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISKKFGDMSYSIRHSISMPAMRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLSSTAHASAQSLAGGSRRTKEEELQC
What are the official names of this protein?
Tumor protein D53, hD53, Tumor protein D52-like 1.
What is the protein family that this protein belongs to?
Belongs to the TPD52 family.
Protein: KCY_SHIFL
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQLIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5344_ARATH
Sequence: MGFFFSTRKGLLLIIFICLDIFGSNAQLLPEDEVQTLRTIFRKLQNQTVNIERTSCLDRKWNFVAESTSKLPTSNITCDCTFNASSVCRVTNIQLRGFNLRGIIPPEFGNLTRLTEIDLVLNFLSGTIPTTLSQIPLEILAVTGNRLSGPFPPQLGQITTLTDVIMESNLFTGQLPPNLGNLRSLKRLLISSNNITGRIPESLSNLKNLTNFRIDGNSLSGKIPDFIGNWTRLVRLDLQGTSMEGPIPASISNLKNLTELRITDLRGPTSPFPDLQNMTNMERLVLRNCLIREPIPEYIGTSMTMLKLLDLSSNMLNGTIPDTFRSLNAFNFMYLNNNSLTGPVPQFILDSKQNIDLSYNNFTQPPTLSCNQLDVNLISSYPSVTNNSVQWCLRKDLPCPGDAHHSSLFINCGGNRLKVDKDEYADDLNKRGASTFSSVSERWGYSSSGAWLGNDGATYLATDTFNLINESTPEYYKTARLASQSLKYYGLCMRRGSYKVQLYFAEIMFSNDQTYSSLGRRLFDIYVQGILLERDFNIAQRAGGVGKPFLRQVDEVQVNGSTLEIHLKWTGKGTNVIPTRGVYGPLISAITVTPNFKVDTGKPLSNGVVAGIVIAACVAFGLLVLVILRLTGYLGGKEVDENEELRGLDLQTGSFTLKQIKRATNNFDPENKIGEGGFGPVYKGVLADGMTIAVKQLSSKSKQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKVCIGIAKGLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLDEEENTHISTRIAGTIGYMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFIYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPMSSVVSMLQGKIKVQPPLVKREADPSGSAAMRFKALEHLSQDSESQVSTYTRNKEHKSSSSMDGPWVDSSFSDPSKDVSLLQQEEGNSSSSSRRLLDDLTDVEIE
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At1g53440.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PSMD2_DICDI
Sequence: MPQKEVTIPVPAKGGSNKEEDKKDNKDTEEKNTTTNTTTKDNKKDKKKDKKEETLSPEDEKLKNDLELLVERSRDEKEEIALAALEALKTEIRSSTSSMTSVPKPLKFLRNHYSTLVDIYKNSKEGKAKTSLADILSVLAMANGNDERDTLKYKLLGSGEAIASWGHEYVKHLATEIGVEYDIKKEENQSVEDLLKLVDEIVPFQMTHNAEPEACDLLLEVEQLSKIFQYIDENNYSRVCLYLFKCSYYVPGPDDINILKVCVEIYIKMKQYPDALRVAMKISDPELITEIFKLVENNKSILQQLGFLVARQKIVPDNFNYDSISDIINNSKLSEYFMNLATDLDIREPKLPEEIFQSHLDSTSAIADSARMNLASSFVNAFVNAGFGKDKLMTAEEDTKWWFKNRELGILSTVASTGMVVLWDIDGGLTKIDKFLYSQEKHCSNGALMAIGMLTSGIRSEMDPALSLLAEHINSSNTGTRISAIFGLGLAYAGTQRQDLMSLLSPCLDDDKEKMEFIGIVGLALGLIFIGSCDPELSTLFVQTLIQRGTAASESHARFLHLGLGLLYLGKQDAAELALETLKAIEGKGGEYARLTVEACAYAGTGNVLKVQNMLHFCSDGQENPHHGLAVLSIALIAMGEELGSDMCLRMFDHLLQKGNVHIKRAIPLALGLLSPSNPRIAIMDILSKLSHDNDPEVAQGAILSLGLIGAGTNNARIGGMLRALAVFYGKDVHLFFVRIAQGLLHLGKGTMTINPYHSDRTLMSPVAVGGLLALLHAGLDIKNILSTQSHYLFFSIVCSMYPRMLMTLDEDLKPLPVSVRVGQSVDIVGLAGKPKTITGFQTHTTPVLLGYNERAELATDDYIPLTNILEGIVILKPNPNASVTSPLASKKN
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 2.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S2 family.
Protein: Y2167_ARCFU
Sequence: MVINRMIGKIAAFRKMPVSDFKFDLNPRIKKRLEIMKENMKGGVMFIPDVGVVWVTPKPSRIISLENEREVGEEILKVVMQKYKTNINFSELGWKLGGMGLENDGFLRTSVKGVDNNQGAVFRVDDPKCWDDIKAAESSMEKNRPKDYPWDSNVDNRDVLDCSSESGCAHIVNQILEENEAVYYSGHGSNYCILIKGEKNSNKINFCSKDVAYGRQTRLFVVSACYAGNGLAEWLVEKWVRCVIADDGELYDYNYWSPCAAWADAFWDRVTGNVDAGYRRTPHEARIETNNLFGWIPRNCNLDVERGDCNFYI
What are the official names of this protein?
Uncharacterized protein AF_2167.
Protein: STKLT_ARATH
Sequence: MATPTELGFSSPGGGGDDSDDNPPQKRTSKRTASETATEEETKKKKKKKTKHNTKMASPPSNRIWNEEDELSILKGLVDFRAKTGLESKIDWDAFYCYVKGSIHVKVSKCQLMSKTRKLKKKFLDQMEKIDQGNDPHFTRSSETEAFGYSMMIWRKIDAEYTNGVMDKAHQSESGEEVFEEDEEVALIDKGAAKSGKSPHEAVVVVDKITTKKNGTAGKESDDDDDDVLCAVRDAFETTMMSQGLSDYQKKLQLEKLMNLGTGKRRELSNEWKALCVEELKLNINKLRFSAKLAEAANDGK
What is the function of this protein?
Probable transcription factor.  May play redundant roles with GEBP and GPL1 in cytokinin responses by regulating the transcript levels of type-A ARR response genes.  Involved in stress responses (PubMed:21875893).  Plays a repressive role in cell expansion by counteracting the positive role of CPR5 in this process, but does not regulate cell proliferation or endoreduplication (PubMed:21875893).
What are the official names of this protein?
GLABROUS1 enhancer-binding protein-like 2, Protein GPL2, Storekeeper-like protein At5g14280.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL18B_YEAST
Sequence: MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMGPHKGKAPRILSTGRKFERARGRRRSKGFKV
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L18-B, Large ribosomal subunit protein eL18-B, RP28.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1864_ARTBC
Sequence: MRFSTLVSLAAWAAAALACDSCSEPGKPAEHKRLVRRMQPEALGALTKPKGPLEWGQINFLHTTDTHGWLEGHLKEQNYGADWGDYSSFVKHMRQKADRLRVDLLLIDCGDLHDGNGLSDSTSPNGVISNEIFSRVDYDLLSIGNHELYVTDVAYETFANFSKVYGERYVTSNVQIINKETGEYEYIGSKYRYFTTKHGLKVMAFGVLFDFTGNSNVSKVIKAADLVQESWFIDAVKTPKPVDLFIIFGHTPARTDDKFPTLRTLRQKIQELRPGVPIQAFGGHNHVRDFVVYDETSTALGSGRYCETLGWLSMTGINSRTFRGSMKPRGVPNPTRRAIKGNATTSTQPYQHPRKGLDLRYARRYLDWNRLTFAYHASKSQDRQFDTQKGLKITHDITDARKQLNTSTVLGCVPETYCMSCVPFEAKNNIYQLVIDMLAKVVVKEDRADKPRLLLLNTGGVRFDLVKGPFTKDDEYIVYPFKNQFQYLPDVPYSIAKELLDALNKGPYQRRSEEYSPMAPQLSTNEVCANPSPEFVQLKRREAPQPYRPITRRTIDSSMLYPGYVTSDDFGLDGDDTPHSKIPYFKVPIDIQANASFPTNGSMPTVVDLAFVDYIGAKYVIPALNKLGGKYSASDIQSYKDFGSSSFLREYALEFWQEGLPNCTTN
What are the official names of this protein?
Secreted protein ARB_01864.
What are the subcellular locations of this protein?
Secreted.
Protein: HLDE_METCA
Sequence: MILPDFSLARVLVVGDLMLDRYWFGGASRISPEAPVPVVRVESSEERIGGAGNVALNLAALGGEVDLLGYAGEDEAAAALERLLAVAGIRSHIERCPAVATITKLRVVSRQQQLIRLDFEDGFAHLDPAPLVTRFRALLEETGVVVLSDYAKGTLACVEEFIAASRRAGKPVLVDPKGVDFDRYRGATLLTPNLSEFEAVVGACCDDAEIERKGRALMTRLDLEALLVTRGEHGMSLLRPTAGALHLPAHGKEVYDVTGAGDTVISVLAAALAVGRPLTDAVALANLAAGIVVGKLGTASVSPEELAIAIHGQRAPRRGAITLAELLDVLIPLRRAGERIVVTNGCFDLLHPGHVHYLEQARALGDRLIVLVNGDDSVRRLKGAGRPVNPLPHRMAMLAALESVDWVVAFDGDTPRDEICAIRPHVLVKGGDYADITAIVGHDCVLETGGEVRILDFVEGHSTTRIIEAIRNG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: YBEY_PSEPF
Sequence: MLELDLQIATEAPAPTEAEFRQWCELALRQRTADSEMTIRLVDEDEGRELNHTWRHKDYATNVLSFPAEVPDEFLDIPLLGDLVICVAVVEREATEQGKELKAHWAHLVIHGCLHLLGYDHIDDEEAEEMEALERELLAELGYPDPYADDETETSPTVTTKDSE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_SHEB9
Sequence: MKIGIIGAMEPEVAHLIAAMTNATSQTIAGIEFIAGTLAGKDVVVTRSGIGKVAASIATTLLIEKYAPDAVINTGSAGGFVDTLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFIPAAHLVEAANKAIAQLGEVKAIEGLICTGDSFICDPVRTQAMLKNFPTMAACEMEGAAIAQVCHQFGVPFVVIRSLSDNANNDSPVDFDSYIVKAGYHSALMVMLLLEQLNPSAVK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: THIC_ARATH
Sequence: MAASVHCTLMSVVCNNKNHSARPKLPNSSLLPGFDVVVQAAATRFKKETTTTRATLTFDPPTTNSERAKQRKHTIDPSSPDFQPIPSFEECFPKSTKEHKEVVHEESGHVLKVPFRRVHLSGGEPAFDNYDTSGPQNVNAHIGLAKLRKEWIDRREKLGTPRYTQMYYAKQGIITEEMLYCATREKLDPEFVRSEVARGRAIIPSNKKHLELEPMIVGRKFLVKVNANIGNSAVASSIEEEVYKVQWATMWGADTIMDLSTGRHIHETREWILRNSAVPVGTVPIYQALEKVDGIAENLNWEVFRETLIEQAEQGVDYFTIHAGVLLRYIPLTAKRLTGIVSRGGSIHAKWCLAYHKENFAYEHWDDILDICNQYDVALSIGDGLRPGSIYDANDTAQFAELLTQGELTRRAWEKDVQVMNEGPGHVPMHKIPENMQKQLEWCNEAPFYTLGPLTTDIAPGYDHITSAIGAANIGALGTALLCYVTPKEHLGLPNRDDVKAGVIAYKIAAHAADLAKQHPHAQAWDDALSKARFEFRWMDQFALSLDPMTAMSFHDETLPADGAKVAHFCSMCGPKFCSMKITEDIRKYAEENGYGSAEEAIRQGMDAMSEEFNIAKKTISGEQHGEVGGEIYLPESYVKAAQK
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, chloroplastic, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Protein PYRIMIDINE REQUIRING, Thiamine biosynthesis protein ThiC, Protein THIAMINE C.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RSXD_ECO27
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTLVQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGTVFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDTIQVIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEEIMQYPIYSGILAGAGWQWVNLAWLAGGVWLLWQKAIRWHIPLSFLVTLALCATLGWLFSPDTLAAPQIHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: X_HBVH3
Sequence: MAARLCCQLDPARDVLCLRPVGAESCGRPLSWSPGALPPPSPPSVPADDGSHLSLRGLPACAFSSAGPCALRFTSARRMETTVNAPQSLPTTLHKRTLGLSPRSTTWIEEYIKDCVFKDWEESGEELRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: KREM1_RAT
Sequence: MAPPAARLALLSAAALTLAARPAPGPRPSPECFTANGADYRGTQSWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKHGEAASTECNNVCFGDHTQPCGGDGRIILFDTLVGACGGNYSSMAAVVYSPDFPDTYATGRVCYWTIRVPGASRIHFNFTIFDIRDSADMVELLDGYTHRVLVRFDGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQATKEEPPQERPAINQTLAEVITEQANLSVSAAHSSKVLYVITSSPSHPPQTVPGSHSWVPSVGASGHRVEGWTVYGLATLLILTVTAVVAKILLHVTFKSHRVTASGDLRDCRQPGTSGEIWTIFYEPSTTISIFKKKLKGQSQQDDRNPLVSD
What is the function of this protein?
Receptor for Dickkopf proteins.  Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.  In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane.  Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1.  Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation.  Modulates cell fate decisions in the developing cochlea with an inhibitory role in hair cell fate specification.
What are the official names of this protein?
Kremen protein 1, Dickkopf receptor, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RRAA_SERP5
Sequence: MKYDTSELCDIYHEEVNVVEPLFSNFGGRTSFGGQITTVKCFEDNGLLFELLEENGRGRVLVIDGGGSVRRALINAELARLATQNEWEGIVVYGAVRQVDDLEEMDIGIQAMAAIPVGAASESIGESDIRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPA_CAMFO
Sequence: MQDNRFFILMILLVFSTSLNQGQKLKANDRRSAGLVPYPRIGRNSEISSFSRSERALGLIHQPRIGRSDVSSFDNLNRFHDLSSDADIEFYAMDMDPLLSPDYEDYASKPIALKYADKLQKDNSWLMPDHIHGYKDFHFAQKINDPRLYYSILRDSRNTQGQGGYTPRLGRENERDTANFL
What is the function of this protein?
Periviscerokinins mediate visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
CAPA peptides.
What are the subcellular locations of this protein?
Secreted.
Protein: MDH_SHEON
Sequence: MKVAVLGAAGGIGQALALLLKTQLPAGSKLSLYDIAPVTPGVAVDLSHIPTAVEIKGFAGEDPTPALVGADVVLISAGVARKPGMDRSDLFNINAGIVRNLIEKVAVTCPKALVGIITNPVNTTVAIAAEVMKKAGVYDKNRLFGVTTLDVIRSETFIAELKGLNVADVKINVIGGHSGVTILPLLSQVEGVTFSDEEVASLTKRIQNAGTEVVEAKAGGGSATLSMGQAACRFGMSLVRGLQGEANVVECAYVDGGSEHAEFFAQPVLLGKNGIEKVLPYGEVSAFEANARDSMLDTLKGDIKLGVDFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: RSMH_SALEP
Sequence: MMENFKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAQTINDPRFSIIHGPFSALADYVAERELTGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTFGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLSVLAPGGRLSIISFHSLEDRIVKRFMREQSRGPQVPAGLPMTEAQLKKLGGRELRALGKLMPGEKEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_PHOV8
Sequence: MLENLEKYKIILASNSPRRKELLSGLGIKYEVKTLPGIEETYPDTLKAEEIPLYIACEKAAAYRNTMHPDELIITADTIVWLDGVVMGKPHNEDDARQMLWKLSGKTHQVITGVCLTTVGAQRSFSAVTEVTFAELSDEEIDYYIRVYKPMDKAGSYGIQEWIGFIGVRGISGSYFNVMGLPVQRLYTELKKL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_DESOH
Sequence: MAGNTFGELFRVTTWGESHGPGIGVVIDGCPPGLALDEAGVQKMLDRRKPGGGSIASTARKEADRAVILSGVFEGKTTGTPILIMAHNRDARSSAYTDIAGLFRPGHGDITYTAKYGIRDWRGGGRASARETFGRVAAGAVAAELLRLSGISVAAYTLELGGIRATTIDVGQVDQNMFGCPDSTVMAAMTDRVTQVKRRGDSVGGIVEVRADGVPAGLGEPVFDKLDADIAKALMSIGAVKGVEIGAGFEASGMTGSRSNDEITPQGFATNNAGGILAGISNGDRIVARAAVKPIPSIGITQQTVDTNGKPASISIKGRHDISAIPRINVVCEAMVCLVLADHLLRQKAISWTR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RLMH_STRMK
Sequence: MKARLIATGERAPSWVAQGFAEYQKRLSHWLPFELVEIEPGLRGKGRDARRATEDEGRRVIAALPKNAYVVALDVPGRQLSSEQLAQRLEHWRGQGRDLAFLIGGPEGHSPEVSALADEKWSIGPLTLPHMLVRLVVAEQLYRAAAMIANHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.