PharMolix/UniProtQA huggingface dataset:
Protein: RL22_ECO27
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CH60_RICPR
Sequence: MTTKLIKHGSKAREQMLEGIDILADAVKVTLGPKGRNVLIEQSFGAPKITKDGVTVAKSIELKDKIKNAGAQLLKSAATKAAEVAGDGTTTATVLARALAREGNKLVAAGYNPMDLKRGMDLAVNAVVEEIKRSSKKINSQEEIAQVGTISSNGDKEIGEKIAKAMEEVGKEGVITVEEAKNFSFDVEVVKGMMFDRGYLSPYFVTNSEKMVAELENPFILLFEKKLSNLQPMLPILEAVVQSQRPLLIIAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMMEDIAILTKGELITEDLGMKLENVNIKNLGTAKRVTISKENTVIVDGNGDKKNIEDRVLQIKSQIAETTSDYDKEKLQERLAKLSGGVAVLKVGGATEVEVKERKDRVEDALAATRAAVEEGVVAGGGVTLLHASQTLTKLKVENKDQQAGIEIVIEALKDPLKQIVKNAGENGGVVVGKLLEHNDKNYGFNAQDMQYVDMIKAGIIDPAKVVRTALQDAASVASLIITTETLIVDEPSDKEEPMPMRGGMGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THT2_ORYSJ
Sequence: MAVAVEITRSEVLRPSETLAAGGGGKRSQLTVFDRAAMDWYIPAVFAWDGAAAPSNDEVKGGLAAVLARYPHLAGRFDVDERGRRCFNLNNAGVRVLEATVAADLADALAHDVAAHVNELYPKADMENADEPVFQVQLTRYACGGLVIGTACNHQVSDGQSMSFFYVAWAAAVRSAGATLPTPFVDRAAIAVPRGPPAPAFDHRNIEFKGEHSWTHSYGSLPLERIRNLAVHFPDEFVAGLKSHVGARCSTFQCLLAHAWKKITAARDLSPEEYTQVRVAVNCRGRASPAVPMDYFGNMVLWAFPRMRVRDLLSSSYAAVVGVIRNAVARVDEQYIQSFVDFGEVAAGDELTPTAAPPGTVFCPDLEVDSWLGFRFHDLDFGRGPPCAFLPPDVPVEGLLIFVPSCAAKGGVEMFMALDDVHVEAFRQICYSMD
What is the function of this protein?
Hydroxycinnamoyl transferase that catalyzes the transfer of an acyl from p-coumaryol-CoA to tryptamine, to produce coumaroyl tryptamine.  Serotonin and tyramine serve as acyl acceptors in vitro.  Can use caffeoyl-CoA, and to a lesser extent feruloyl-CoA, as acyl donors.
What are the official names of this protein?
Tryptamine hydroxycinnamoyltransferase 2, OsTHT2.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: KN14F_ARATH
Sequence: MDQGAMETLPEKPSEDEFSLALRNGLILCNVLNKVNPGSVLKVVENPITPAIQYADGAAQSAIQYFENMRNFLKAVEDMQLLTFGASDLEKGGSSNKVVDCILCLKGFYEWKQAGGVGVWRYGGTVRIVSFNRKGSSPPQYGIGSESTTDESVSLDESESSQYDQLLDFLHLSNEISAEESETAISLAFLFDHFALQLLHGYLKESDGINDMPLNEMVIDTLLNRVVKDFSAILVSQGAQLGSFLRKILKCDNGDLSRSEFLAAVFRYLQHRKDLVSKEFSKFCKCGGKLEFSRLNAREFSPGHVEAIGLQQKELEEVKSNFVETRSQVKQMQSEWQKELQRIVHHVKAMEVTSSSYHKVLEENRLLYNEVQDLKGTIRVYCRVRPFFQEQKDMQSTVDYIGENGNIIINNPFKQEKDARKIFSFNKVFGQTVSQEQIYIDTQPVIRSVLDGFNVCIFAYGQTGSGKTYTMSGPDLMTETTWGVNYRALRDLFQLSNARTHVVTYEIGVQMIEIYNEQVRDLLVSDGSSRRLDIRNNSQLNGLNVPDANLIPVSNTRDVLDLMRIGQKNRAVGATALNERSSRSHSVLTVHVQGKELASGSILRGCLHLVDLAGSERVEKSEAVGERLKEAQHINKSLSALGDVIYALAQKSSHVPYRNSKLTQVLQDSLGGQAKTLMFVHINPEVNAVGETISTLKFAQRVASIELGAARSNKETGEIRDLKDEISSLKSAMEKKEAELEQLRSGSIRNTTECQRARAVSPFHLPRTGNGAGTKAEASPQPNDGTRSYETRSCSTGKQRKSGFPSALRNREASPRMPNLAEERLNPSPSRRSLSTDRASTIKSRNKPDVTQNLPVSRTPFPARVPVVKSFSTVPLNPSAENNHRLHTDNSSEAFQNHQKLSARKLFPEIEEEHIRHALHIRQGGVKKTRAESSKAKAKQPSPARFQKLDVGISLRSDADSEAKVGNYQTQKGNNNHNVIHSRFQNFDVGISLFSDLCAGDKSDSTLKSDSSETDNEPPSKSKNAQRNSSKNSLNHKLRTIYAHEDTSLVDDKPSNGTAHIKEGNNNISMPEFRRSRSTHHARFMVP
What is the function of this protein?
Required for keeping the ATP levels stable and balancing the aerobic respiration pathways during seed germination at low temperature.
What are the official names of this protein?
Kinesin-like protein KIN-14F, AtKIN14h, Kinesin KP1, Kinesin-like protein 1, AtKP1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Mitochondrion. Note=Associated with VDAC3 in mitochondrion.
Protein: RUVB_MYCPA
Sequence: MTAHDADWSDRDVSGALVPGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELQQVLARSAGILGIELGAEAAEEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALAVYDVDELGLDRLDRAVLTALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPRGRVATAQAWTHLGMVPPAGAAGLGQPGLFD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ATPB_CAMJE
Sequence: MQGFISQVLGPVVDVDFNDYLPQINEAIVVNFESEGKKHKLVLEVAAHLGDNRVRTIAMDMTDGLVRGLKAEALGAPISVPVGEKVLGRIFNVTGDLIDEGEEISFDKKWAIHRDPPAFEDQSTKSEIFETGIKVVDLLAPYAKGGKVGLFGGAGVGKTVIIMELIHNVAFKHSGYSVFAGVGERTREGNDLYNEMKESNVLDKVALCYGQMNEPPGARNRIALTGLTMAEYFRDEMGLDVLMFIDNIFRFSQSGSEMSALLGRIPSAVGYQPTLASEMGKFQERITSTKKGSITSVQAVYVPADDLTDPAPATVFAHLDATTVLNRAIAEKGIYPAVDPLDSTSRMLDPNIIGEEHYKVARGVQSVLQKYKDLQDIIAILGMDELSEEDKLVVERARKIEKFLSQPFFVAEVFTGSPGKYISLEDTIAGFKGILEGKYDHLPENAFYMVGNIDEAIAKADKLKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FTSW_LEGPH
Sequence: MNTMRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIRQACYLFVGLLLALIVVRTDSSFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFIKPMAILAVVSVLLLLEPDFGATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYNSGYQLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSILVIRGLNIGYTAYTQERHFASYTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGASMVINCIVIALLLRIDHENRWQSLGLRPLTA
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: YETS2_MOUSE
Sequence: MSGIKRTIKETDPDYEDVSVALPNKRHKAIESSARDAAVQKIETIIKEQFALEMKNKEHEIDVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGLKTFDPMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNVDVEERPPSTGEQRPSRKAGRDTSSISGSHKRELRNADLTGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDSVYPQSSESDVCDAPPPTLTLPAAVKASAVAQSPEPAAAAPVGEGFPETTEAERHSTFYSLPSSLERTPTKVTTAQKVTFSSHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHLKQGTASSGVSNPHVIVDKPGQVIGASTPSTGSPTSKLPVASQASQGTGSPIPKIHGSSFLTSTVKQEESLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGEAPHVSTTGAASQSAFPQYVTVKGGHMIAVSPQKQVISAGEGTTQSPKIAPSKVVGVPVGSALPSTVKQAVAISSGQILVAKASSSVTKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAAAGGSGSSGAGGGSGGGGGSGAGGTPSTSGPGGGPQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTASVVQGTLGVSSSSAQGQQTLKVISGQKTTLFTQAATAGQASLLKLPDNTLKSVPAAPQLAKPGTTMLRVAGGVITAAPSPAVAFSANGAVHQSEGSTPVSSSVGSIIKTPGQPQVCVSQATMATCKGPAAVAGTAASLVSAPSSISGKATVSGLLKVHSAQSSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTTVLPISVPNQAAPSSAPVAIAKVKTEPETPGPNCISQENQVAVKTEESSELSNYVIKVDHLETIQQLLTAVVKKIPLITAKGDDASCFSAKSLEQYYGWNIGKRRAAEWQRAMTVRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRHDGDSIEDVLTQIDSEPECLSSFSTADDLCRKLEDLQQFQKREPENEEEVDILSLSEPLKTNIKKEQEEKQEEMRFYLPPTPGSGFVGDITQKIGITLQPVALHRNMYASVVEDMILKATEQLVSDILRQALAVGYQTASPNRIPKEITVSNIHQAICNIPFLDFLTNKHMGRLNEDQ
What is the function of this protein?
Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.  YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr).  Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.
What are the official names of this protein?
YEATS domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR2_STRP1
Sequence: MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDLVNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEWSKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGAPIVVKADGLALGKGVVVAETVEQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFANGDKFYIMPTAQDHKRAFDGDKGPNTGGMGAYAPVPHLPQSVVDTAVEMIVRPVLEGMVAEGRPYLGVLYVGLILTADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVASEGYPFDYEKGVPLPEKTDGDIITYYAGVKFSENSELLLSNGGRVYMLVTTEDSVKAGQDKIYTQLAQQDTTGLFYRNDIGSKAIRE
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: RPIA_CAEEL
Sequence: MVTSTGPEAELAPIEQAKKRAAFACGEKYVQSGCRLGVGSGSTVKYLVEYLKQGFQNGSLKDIICVPTSFLTKQWLIESGLPVSDLDSHPELDVCIDGADEVDGQFTCIKGGGGCLAQEKIVQTAAKNFYVIADYLKDSKHLGDRYPNVPIEVLPLAAQPLLRSIPRAEGGSCQLRQAVKKCGPIVTDNGNFIIDWQFEKNVSGRDWFAIQQRLANTPGIVETGLFIGCVDAVFFAYSDGSVKEIVNSKKH
What are the official names of this protein?
Probable-ribose 5-phosphate isomerase, Phosphoriboisomerase.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: Y4904_MYCSS
Sequence: MQPGGQPDMSALLAQAQQMQQQLMEAQESLANSEVHGQAGGGLVQVTMKGSGEVTSVAIDPKVVDPDDVETLQDLVVGAIADAAKQVTILAHDRLGPLAGGMGGLGIPGL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Mmcs_4904.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CFXQ1_CYACA
Sequence: MGITPTALEKTDKHTLVNLQEEFNKTKIQEVLDDLNQELIGLKPVKNRIREIAALLLVDRLRQKVGLSSSNPGLHMSFTGPPGTGKTTVATKMADILYKLNYIKKGHLVTVTRDDLVGQYIGHTAPKTKEVLKKAMGGVLFIDEAYYLYKPDNERDYGSEAIEILLQVMENQREDLVIIFAGYKEKMDKFYASNPGLASRVANHVDFPEYRPEELLKIAEMMLQEQQYQLTKEAELVFLDYIKKRMLQPHFANARSVRNAIDRARMRHANRIFNLSSKIVTKSNLTTIQAEDILKSRLFNT
What is the function of this protein?
Necessary for the expression of RuBisCO.
What are the official names of this protein?
Protein CfxQ homolog.
What is the protein family that this protein belongs to?
Belongs to the CbxX/CfxQ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COXX_PARMW
Sequence: MAEAISAALPTRDQVVPSRKRVKLPPWLEVAKPRLIPLLLATTLGGMALTEGWPLSSPRLVCTLGGGALASAAAGVLNCLWEQDLDGRMARTSGRALPSGRLSPTSAFIGAIACTLAAAMLLVSGVNCLAAGLSLLGLCSYVLLYTALLKPRTTQNIVIGGVAGAIPPLVGAAAATGHVGLGGWWLFALVMVWTPAHFWALALLLREDYRAVGIPMLPVVKGPVVTARAIRRYGWATVLLSGFGVLALPTGGVFYGLILLPFNGRLIQMVQRLSMDPDSLMAAKGLFRWSILYLFGICLLLILSRTDLASSFDQQVMFVLQQLPIV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLHA_STRCA
Sequence: FPDGEFLMQGCPECKLGENRFFSKPGAPVYQCTGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKAFTKITLKDNVKIENHTECHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of heterodimeric glycoprotein hormones.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSP_YERPB
Sequence: MTQNLSQLEHNDAFIQRHIGSSVEQQQQMLAAVGASSLSTLIQQIVPADIQLPGPPPVGEAATEHQALAELKGIASQNQCYKSYIGMGYSPVLTPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQLTQDLTGLDLASASLLDEATAAAESMALAKRASKLKDANRFFVADDVHPQTLDVVLTRAETFGFDVIVDRAEKVLELDGIFGVLLQQVGTTGELHDYSALLAELKKRKIITSVAADIMALVLLTAPGAQGADVVFGSAQRFGVPMGYGGPHAAFFACRDEFKRSMPGRIIGVSRDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPQGLQRIAGRIHRMTDILAAGLQHAGLTLRFKHWFDTLTVEVKDKAAVLARALSFGINLRTDIHGAVGITLNETTSREDIQTLFALFVGDNHGLDIDQLDAAVSQHSQSIQDSMLRRDPILTHPVFNRYHSETEMMRYMHRLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAAGYQQMIGQLSQWLVQLTGYDAVCMQPNSGAQGEYAGLLAIRRYHESRNQANRHICLIPSSAHGTNPASAQMAGMSVVVVACDKQGNIDLHDLRQKAEHAGDELSCIMVTYPSTHGVYEETIREVCQIVHQFGGQVYLDGANMNAQVGITTPGYIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIDGMTTQQGAVSAAPFGSASILPISWMYIRMMGADGLKQASQVAILNANYIATRLKNAYPVLYTGHDGRVAHECILDIRPLKEATGISEMDIAKRLIDFGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIEKVAQGEWPLEDNPLVNAPHTQAELVGEWTHPYSRELAVFPVAGVLENKYWPTVKRLDDVYGDRNLFCSCVPISDYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: KTHY_CWPXB
Sequence: MSRGALIVFEGLDKSGKTTQCMNIMESIPSNTIKYLNFPQRSTVTGKMIDDYLTRKKTYNDHIVNLLFCANRWEFASFIQEQLEQGITLIVDRYAFSGVAYAAAKGASMTLSKSYESGLPKPDLVIFLESGSKEINRNVGEEIYEDVAFQQKVLQEYKKMIEEGDIHWQIISSEFEEDVKKELIKNIVIEAIHTVTGPVGQLWM
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: UPPP_CAMJ8
Sequence: MENLNALILGIIEGLTEFLPVSSTGHMILGTTILGIDIDEFWKSFLIIIQLGSILAVIFVFWRKLFQGLDIWLKLAAGFFPTGVIGLFVAKYLNALFNGWVVVGMLIFGGVVFILIELAHKNKQYRINSLEEISFKQAFCIGIFQSLAMIPGTSRSGASIIGGLLLGFNRKVAAEFSFLLAIPTMIIATAYSIYKEPELLSNANSLIPLGIGFITAFVVAVLVIKFFLKFISKFDFIPFGIYRIILGFVFFYLYYSGILNAGSEFKL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYGA_SALG2
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_SHESM
Sequence: MFDILMYLFENYVHSEVELLVDEDELTKELTRAGFHQSEILKALTWLERLAELQEGDKPYLCNHDQHSFRIYTKEEMEKLDVECRGFLLFLEQVKVLNVETREMVIDRVMELDEPALILEDLKWVILMVLFNAPGHESAYEQMEDLIFEQPEEGRLHS
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: SYI_STRMU
Sequence: MKLKETLNLGKTAFPMRAGLPNKEPQWQKQWDEANIYAKRQELNANKPAFFLHDGPPYANGNIHVGHALNKISKDIIIRSKSMSGFRAPYIPGWDTHGLPIEQVLAKKGVKRKEIDLADYLDMCRQYALSQVDKQRQDFKRLGVSGDWENPYITLVPKYEAAQIRVFGAMADKGYIYHGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGKDILDTDTYIVVWTTTPFTITASRGLTVGPDIDYVVVKPANDERKFLVAQALLSELAERFAWDNPQVLATHKGIELDRIVTIHPWDDNVEELVMNGDHVTLDSGTGIVHTAPGFGEDDYNVGVKYGLDVVVTVNERGIMMENAGPDFEGQFYDKVLPTVKEKLGDLLLASEVITHSYPFDWRTKKPIIWRAVPQWFASVSKFRQDILDEIDKVHFYPAWGKTRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHIANLFEEHGSVIWWQREAKDLLPEGFTHPGSPNGEFTKENDIMDVWFDSGSSWNGVLNTREDLGYPADLYLEGSDQYRGWFNSSLITSVAVNGHAPYKSVLSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGAEILRLWVASVDTDSDVRVSMEILGQVSETYRKIRNTLRFLIANTTDFNPYINKIAFEDLRSVDKYMLIKFNQLVSVINRAYSHYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAADDLARRQMQTVFYEILVNITKLLTPILPHTSEEIWSYLEHEEEAFVQLAEMPEAQEFANQDEILDTWSAFMSLRDQAQKALEEARNAKIIGKSLEAHLTVYASEEVKTLLTALDSNIAQLLIVSQLTVTQEQAPKNALVFEDVAFSVEHARGHVCDRCRRIDETVKERPYHVTICNHCAAIVENHFPEAVRQGFESK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V192_BPT3
Sequence: MGTPQSSGLRSIRVAVRKTCTMVNVWPLCSVRSSTMGSRCSKANQLTPCDSTWKTYGNVSWNTVRLASLYSSCLTRTLVMPRSTPYASVTLSCAVLTSRKPQCTTSGFRTVRIAMRSCLTWALRVMTFIAIIRAARTLDSTSNASS
What are the official names of this protein?
Gene 19.2 protein.
Protein: P53_DANRE
Sequence: MAQNDSQEFAELWEKNLIIQPPGGGSCWDIINDEEYLPGSFDPNFFENVLEEQPQPSTLPPTSTVPETSDYPGDHGFRLRFPQSGTAKSVTCTYSPDLNKLFCQLAKTCPVQMVVDVAPPQGSVVRATAIYKKSEHVAEVVRRCPHHERTPDGDNLAPAGHLIRVEGNQRANYREDNITLRHSVFVPYEAPQLGAEWTTVLLNYMCNSSCMGGMNRRPILTIITLETQEGQLLGRRSFEVRVCACPGRDRKTEESNFKKDQETKTMAKTTTGTKRSLVKESSSATLRPEGSKKAKGSSSDEEIFTLQVRGRERYEILKKLNDSLELSDVVPASDAEKYRQKFMTKNKKENRESSEPKQGKKLMVKDEGRSDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECO_STAAS
Sequence: MLMRQKGIIIKAVDYGESDKIITILNEHGAKVPLMARRAKKVKTGLQAQTQLFVYGLFIYNQWRGMGTLNSVDVISQHYKLQMDLFVSSYASLAAETIERSMDEGDIAPYNYQLLQFVLEKIESGTSAQLMSVVVMLKCMKRFGFTASFNRCAVSGNDTQADLIGYSFKFDGAISRQEASKDVHAVILSNKTLYLLDVLQKLPIDKMNSLNIHQEIIDEMSDIILMLYREYAGMFFKSQKLINQLKRLEQ
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: DF226_ARATH
Sequence: MKCGVLFMISCLLITFLVLSHVREVESKTKWGCDMNRPFPGKCGTNGKDTCISDIKKMPGAPKDLVVRCECSQRFVWKGYPPERLCKCQYDC
What are the official names of this protein?
Defensin-like protein 226, S locus cysteine-rich-like protein 2, Protein SCRL2, SCR-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: HRCA_LACPL
Sequence: MITLTERQSLILKAIVRDYTEGGNPVGSKSLVQELPIKVSSATIRNEMARLEDLGLIVKTHLSSGRIPSIKGYRYYVDHILKPEKVDGKDLKVIQHSLGGEFHKIDEIVAQSADILSQLTSYTTFTLRPELKDSRLSGFRLVPLGNHQVMAILVTNNGDVENQTFTIPSDITGDELEPVVRFIDDQLVGLPLQDVLRQLTHEIPLKLAQYLQDPDGFLDIFGSVLSKAASERFYVGGKLNLFNYTDQQSPKELQSLYSLLDQTDRLANVIGPPGQRIQVRIGNEITNDLLKNYSLITATYDVDQHGQGVIALLGPTAMPYSRMIGLMGAFQRELARKLLDYYRYFDE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: NAAA_HUMAN
Sequence: MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
What is the function of this protein?
Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-lauroylethanolamine = N-stearoylethanolamine > N-arachidonoylethanolamine > N-oleoylethanolamine (PubMed:15655246, PubMed:17980170, PubMed:18793752, PubMed:30301806, PubMed:22825852).  Also exhibits weak hydrolytic activity against the ceramides N-lauroylsphingosine and N-palmitoylsphingosine (PubMed:15655246).
What are the official names of this protein?
N-acylethanolamine-hydrolyzing acid amidase, Acid ceramidase-like protein, Acylsphingosine deacylase NAAA, N-acylsphingosine amidohydrolase-like, ASAH-like protein.
What is the protein family that this protein belongs to?
Belongs to the acid ceramidase family.
What are the subcellular locations of this protein?
Lysosome. Membrane; Peripheral membrane protein.