PharMolix/UniProtQA huggingface dataset:
Protein: RECG_STAAC
Sequence: MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSSDEAIEIDYDIDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEINVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.
Protein: RS11_THEVB
Sequence: MAPSAKRSGPRKQKRNVPSGVAHIQSTFNNTIVSITDPNGEVIAWASAGSSGFKGAKKGTPFAAQTAADNAARRAIDQGMRQIEVMVSGPGSGRETAIRALQAAGLEITLIRDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: LGT_NEIMB
Sequence: MITHPQFDPVLISIGPLAVRWYALSYILGFILFTFLGRRRIAQGLSVFTKESLDDFLTWGILGVILGGRLGYVLFYKFSDYLAHPLDIFKVWEGGMSFHGGFLGVVIAIRLFGRKHGIGFLKLMDTVAPLVPLGLASGRIGNFINGELWGRVTDINAFWAMGFPQARYEDAEAAAHNPLWAEWLQQYGMLPRHPSQLYQFALEGICLFTVIWLFSKKQRSTGQVASLFLGGYGIFRFIAEFARQPDDYLGLLTLGLSMGQWLSVPMIVLGIVGFVRFGMKKQH
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL7_ECO5E
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ILVC_CROS5
Sequence: MARMYYDADANLDLLADKTVAIIGYGSQGHAHALNLKDSGINVVVGLYPGSKSRQKAEDAGLKVMNVADAASAADWIMILLPDEVQKAVYQEDIEPNLREGKVLSFAHGFNIHFGQIVPPETVDVIMVAPKGPGHLVRRTYEQGEGVPCLFAVYQDASGQARDRAMAYAKGIGGTRAGILETSFREETETDLFGEQVVLCGGLSALIKSGFETLVAAGYQPELAYFECLHEVKLIVDLIVEGGLAKMRDSISNTAEYGDLTRGPRIVTDETRAEMKQILREIQSGQFAREFVLENQSGKPGFTAMRRQEAEHPIEEVGKDLRAMFSWLKDK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: TAF1L_HUMAN
Sequence: MRPGCDLLLRAAATVTAAIMSDSDSEEDSSGGGPFTLAGILFGNISGAGQLEGESVLDDECKKHLAGLGALGLGSLITELTANEELTGTGGALVNDEGWIRSTEDAVDYSDINEVAEDESQRHQQTMGSLQPLYHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDAITCVSESGEDIILPSIIAPSFLASEKVDFSSYSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLHLFGPGKNVPSVWRSARRKRKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAPPPPPEQCLADDEITMMVPVESKFSQSTGDVDKVTDTKPRVAEWRYGPARLWYDMLGVSEDGSGFDYGFKLRKTQHEPVIKSRMMEEFRKLEESNGTDLLADENFLMVTQLHWEDSIIWDGEDIKHKGTKPQGASLAGWLPSIKTRNVMAYNVQQGFAPTLDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKEEATSNSPSKESKKESSLKKSRILLGKTGVIREEPQQNMSQPEVKDPWNLSNDEYYFPKQQGLRGTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQALENNLFRAPVYLHKMPETDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAKVSPEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSISAEDSDFEEMGKNIENMLQNKKTSSQLSREWEEQERKELRRMLLVAGSAASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSKPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTSQPPDMYDTNTSLSTSRDASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPEGGDGDLADEEEGTVQQPEASVLYEDLLISEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGYGGIRPKQPFMLQHASGEHKDGHGK
What is the function of this protein?
May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 1-like, TAF(II)210, TBP-associated factor 1-like, TBP-associated factor 210 kDa, Transcription initiation factor TFIID 210 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAB_MYCSS
Sequence: MTQQAANALPPVARTYQVRTYGCQMNVHDSERLAGLLEDAGYRRAADGADADVVVFNTCAVRENADNKLYGNLSHLAPRKRSEPQMQIAVGGCLAQKDRDAVLRRAPWVDVVFGTHNIGSLPTLLERARHNRAAQVEIAEALQEFPSTLPAARESAYAGWVSISVGCNNTCTFCIVPSLRGKEVDRRPGDVLAEIQTLVDQGVLEVTLLGQNVNAYGVSFAADERLREDPRMWQSVPRNRGAFAELLRACGRIDGLERVRFTSPHPAEFTDDVIEAMAETPNVCPALHMPLQSGSDRILRAMRRSYRAEKYLGIIDRVRAAIPDAAITTDLIVGFPGETEEDFQATLDVVAASRFSSAFTFQYSKRPGTPAADMPGQLPKAVVSERYQRLIELQERISLEENQAQVGRTLELLVATGEGRKDAATARLSGRARDGRLVHFAPGAAADEPLARRAFDQVRPGDVVTTTVTGAAPHHLIADGALLTHRRTRAGDAHAAGLRPRTGVGLGIPGVGAPAPAPVTTGCAL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBPA_BACSU
Sequence: MSHFKNYQISHDILRALEGLGYTEPTKVQQSVIPAALERKDLVVKSQTGSGKTASFGIPLCELANWDENKPQALILTPTRELAVQVKEDITNIGRFKRIKATAVFGKSSFDKQKAELKQKSHIVVGTPGRVLDHIEKGTLPLDRLSYLVIDEADEMLNMGFIEQVEAIIKHLPTERTTMLFSATLPQDIEKLSRQYMQNPEHIEVKAAGLTTRNIEHAVIQVREENKFSLLKDVLMTENPDSCIIFCRTKEHVNQLTDELDDLGYPCDKIHGGMIQEDRFDVMNEFKRGEYRYLVATDVAARGIDIENISLVINYDLPLEKESYVHRTGRTGRAGNKGKAISFVTAFEKRFLADIEEYIGFEIQKIEAPSQEEVARKKPEFLAKLNDRPESKKDKSEELNKDIMKLYFNGGKKKKIRAVDFVGTIAKIDGVSADDIGIITIMDNASYVEILNGKGPHVLKVMKNTTVKGKQLKVNKANK
What is the function of this protein?
DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit.  Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes (Probable).
What are the official names of this protein?
ATP-dependent RNA helicase DbpA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DbpA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_ECOLU
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNLPEQVARTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: FADB_ECOHS
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLIEGAMAILRQAINGDLDWKAKRQPKLEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: NO20_SOYBN
Sequence: MRVVLITLFLFIGAAVAEDAGIDAITPEEGKANNIIEAYESPRFQKFVTHCSSHVTQTCSGNDPLNNQEASRMNSPFGLSFCLFDSMEKCLADHKASLKDPQDNNNLASMSSLPGSIQNQPLLIETVKFRAVLKTCSHVSARYCFTNPNVATSALADCLMPSLTHCVYPSSSILLPPPPPPPPLI
What are the official names of this protein?
Nodulin-20, N-20.
What is the protein family that this protein belongs to?
Belongs to the nodulin 20 family.
What are the subcellular locations of this protein?
Symbiosome, peribacteroid membrane. Symbiosome, peribacteroid space.
Protein: YEBC_SHISS
Sequence: MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPDANPRLRAAVDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECLSDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAEDVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMRLIDMLEDCDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YebC.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_HAEDU
Sequence: MMIAGAEANVEPLVRQSSKPEFGDYQANGAMAAAKKLAMNPREFAQKILDNLDVSDMVDKLEIAGPGFINIFLKPSWLAKQANFALQAVNFGIKTAQPQTILIDYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNNVIRANHVGDWGTQFGMLIAYLEKMENEQASEMQLSDLEAFYRAAKESYDSDQIFAEKARNYVVKLQSGDEYCRTMWKKLVDITMHHNQENYDRLNVTLTEKDVMGESLYNPMLPEIVADLKAKGLAVEDNGAVVVFLDEFKNKDGDPMGVIIQKSDGGFLYTTTDIAAAKYRYETLKVDRALVFSDSRQAQHMQQAWLITRKAGYVPASFSLEHPFFGMMLGKDGKPFKTRSGGTVKLKDLLDEAVERADKLISARSTNLTVAEKSAVVEAVAIGSVKYSDLSKNRTTDYVFDWDNMLTFEGNTAPYMQYAYTRIRSIFARAEIDPDTLTGEMQLTEEKERTLALKLLQFEEALTAVAKEGMPHILCQYLYELAGIFSSFYEACPMLNADEAIKHSRLRLASLTAKTLKQGLDLLGIKTVEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPY1_YEAST
Sequence: MSTAVTFFGQHVLNRVSFLRCSKEFIKKSLNHDSTVFIPFIEGEALISPENGDLVQLSNSVKSYKNILSAIVPLYTTLLNTTRSRSDESGINVTFLGLLEGTDSAFNFEWSNISYKGTPYFGLDIRVTESTLFKKVDFEPIFSYPKVTRDHIFKQTNEDASLYSQGKMYLDWLAKYKFCPGCGSPLFPVEAGTKLQCSNENRNVYCNVRDARINNVCFPRTDPTVIIALTNSDYSKCCLARSKKRYGDFVLYSTIAGFMEPSETIEEACIREIWEETGISCKNIDIVRSQPWPYPCSLMIGCLGIVQFNSKNEVINLNHDDELLDAQWFDTTEIIQALDKYAGGYRVPFKNDINLPGSTTIAFQLINHVCENYKNLRKTSSSHL
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some RNAs; in contrast to the canonical N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Mediates the hydrolysis of some nucleoside diphosphate derivatives (PubMed:11361135).
What are the official names of this protein?
NAD-capped RNA hydrolase NPY1, DeNADding enzyme NPY1, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
What are the subcellular locations of this protein?
Peroxisome.
Protein: KATG_GEOTN
Sequence: MENQNRQNASQCPFHGSITNQSSNRTTNKDWWPNQLNLSILHQHDRKTNPHDEEFDYAAEFQKLDYWALKEDLRKLMTESQDWWPADYGHYGPLFIRMAWHSAGTYRIGDGRGGASTGTQRFAPLNSWPDNANLDKARRLLWPIKKKYGNKISWADLFILAGNVAIESMGGKTIGFGGGRVDVWHPEEDIYWGAEKEWLASERHSDDGELEHPLAASVMGLIYVNPEGPDGKPDPKAAARDIRETFRRMGMNDEETVALIAGGHTFGKAHGAGPATHVGPEPEAAPIEAQGLGWMSSYGKGKGSDTITSGIEGAWTPTPTQWDMSYFDMLFGYDWWLTKSPAGAWQWMAVDPNEKDLAPDAEDPSKKVPTMMMTTDLALRFDPEYEKIARRFHQNPEEFAEAFARAWFKLTHRDMGPKTRYLGPEVPKEDFIWQDPIPEVNYELTEAEIEEIKAKILNSGLTVSELVKTAWASASTFRHSDKRGGANGARIRLAPQNEWEVNEPERLAKVLSIYEDIQRELPKKVSIADLIVLGGSAAVEKAARDAGFDVKVPFSPGRGDATQEQTDVESFAVLEPFADGFRNYQKQEYSVPPEELLVDKAQLLGLTAPEMTVLVGGLRVLGANYRDLPHGVFTDRIGVLTNDFFVNLLDMDYEWVPTDSGIYEIRNRKTGEVRWTATRVDLIFGSNSILRSYAEFYAQDDNQEKFVRDFINAWVKVMNADRFDLVKKARESVTA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: Y5821_DICDI
Sequence: MNNLITENQNLNIKDQICEIEIKNTIVFNKNNINNNNNNNSNSSIKKCLKSSFNESINENNILTFEIQPNGTYKNYFSNEIPNEIQHLIVEEELYKQFIVKINNKRLPIYYQIMLILMILSMILIIPLFFIVFTFSPRLAFGICLTLLFYIAIFILTNGLIEKRIVLILTYFVLYKKKNYKIEEIILNYNSFLINKKIPILFRLIYKENHVVPGFDKISIEVTFINE
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0285229.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PA39C_DAMDA
Sequence: DVGPSTLANN
What are the official names of this protein?
Pregnancy-associated glycoprotein 39C, FdPAG39C.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RL15_CHLAD
Sequence: MKLHDLRPAEGSHRKRKRIGRGHGSGKVKTGGKGMMGQKARSGPGPYRTFEGGQNRLVKRMPFKRGFTNKFRVEYEVVNVGSLVDWPTELEVTPETLLARRLVRRKKMPVKILGDGELNQPLVIKAHKFSASARQKIEAAGGKAIDLTWIVERHSRSRGPNPSMRNARQS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LEPA_PROM4
Sequence: MTNVPVSRLRNFCIIAHIDHGKSTLADRLLQDTATVASRDMQDQFLDNMELERERGITIKLQAARMKYTATDGNEYVLNLIDTPGHVDFSYEVSRSLQACEGALLVVDASQGVEAQTLANVYLALENDLEIIPVLNKVDLPGSDPEKIKKEIESIIGLDTSQAISCSAKTGLGVTDILQAVVERVPPPKDTLEQATQALIFDSYYDPYRGVIVYFRVTAGSISARDQILLMASKKSYELDEIGIMAPDQQKVNELHAGEVGYLAASIKAVSDARVGDTITLLNAPAADPLPGYTEAKPMVFCGLFPTDADQYPDLREALEKLQLSDAALKYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYDLDLIVTAPSVIYQVNMLNGEALMIDNPATLPDPQHRDSIEEPYVRMEIYAPNDYNGTLMGLCQDRRGEFVDMKYITTDRVTLIYEMPLAEVVTDFFDQMKSRTKGYASMEYHLIGYRKNDLVRLDVLINSDKADPLTTIVHRDKAYGVGRALVDKLKELIPRQQFKIPLQASIGSRIIASQNISALRKDVLAKCYGGDISRKKKLLQKQAKGKKRMKSMGKVDVPQEAFMAVLKLNS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACCA_RUMCH
Sequence: MSAYDKVMAARSKDRPTSKDYIKNIFTNFTEFHGDRRFGDDNAVVAGIGLLGNRPVTVIALEKGQDTKERLSRNFGSAHPEGYRKALRQMKLAEKFNRPVVCFIDTSGAYCGIGAEERGQGQAIAENLITMIDLKVPIISILIGEGGSGGALALAVADEVWMLENAIYSVISPEGCASILWKDSARVKEVAECLKLTADDLYSLGVTDMVIKENGGDFIRVYEDLSNKILHSINKYYEFSADKLVKMRFEKYQRLGMITQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_SINMW
Sequence: MQFTDTIYALSSGSPPAGVALIRVSGPATADALARLCGPLPPARVATLRTIRTRNSDILDSGLVLYFPGPASFTGEDCCELQVHGGRAVVSAILDELAAMDGLRHAEAGEFARRAFQNGKLDLVEVEGLADLIAAETEMQRRLAVEQSGGGQSALYAGWARRLTHARAMIEAELDFADEDDIPGSVSAAIWTDIGRLREEIDEHIARAGVAEIIRDGLKIVIAGEPNAGKSSLLNALAQRDIAIVTEIAGTTRDVLSVDLSLAGFSVKLFDTAGLRETDEVVEREGIRRARQVIADADLVLLLSEKPSDFRLDEWQPGKSVPVIRVATKVDRPMPRWKTSEADVFLSTRTGEGMDKLLAMLQAHLPDLAGNTALSMPSRRRHVDCLRQAGAALVRSMEARELELQAEQLRQAGDALGRITGRVDVEKLLDVIFSEFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADCK1_HUMAN
Sequence: MARKALKLASWTSMALAASGIYFYSNKYLDPNDFGAVRVGRAVATTAVISYDYLTSLKSVPYGSEEYLQLRSKSWPVFLQVHLRSARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEIRQVIREDLGKEIHDLFQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDILLMEVLVLAVKQLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVLLMEFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTGKAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRLGAGDLYPLFACMLTARSWDSVNRGISQAPVTATEDLEIRNNAANYLPQISHLLNHVPRQMLLILKTNDLLRGIEAALGTRASASSFLNMSRCCIRALAEHKKKNTCSFFRRTQISFSEAFNLWQINLHELILRVKGLKLADRVLALICWLFPAPL
What is the function of this protein?
Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (PubMed:31125351).  The action of this enzyme is not yet clear (Probable).  It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable).
What are the official names of this protein?
AarF domain-containing protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRTN3_MOUSE
Sequence: MSGSYPSPKGIHPFLLLALVVGGAVQASKIVGGHEARPHSRPYVASLQLSRFPGSHFCGGTLIHPRFVLTAAHCLQDISWQLVTVVLGAHDLLSSEPEQQKFTISQVFQNNYNPEENLNDVLLLQLNRTASLGKEVAVASLPQQDQTLSQGTQCLAMGWGRLGTQAPTPRVLQELNVTVVTFLCREHNVCTLVPRRAAGICFGDSGGPLICNGILHGVDSFVIRECASLQFPDFFARVSMYVDWIQNVLRGAEP
What is the function of this protein?
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro).  By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration.  May play a role in neutrophil transendothelial migration, probably when associated with CD177.
What are the official names of this protein?
Myeloblastin, Proteinase 3, PR-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
What are the subcellular locations of this protein?
Lysosome. Secreted. Cell membrane; Peripheral membrane protein; Extracellular side. Membrane raft; Peripheral membrane protein; Extracellular side. Note=Localizes predominantly to azurophil granules (primary secretory granules) in neutrophils. Secreted upon neutrophil stimulation by TNF-alpha, lipopolysaccharide (LPS), fMLP and CXCL8/IL8 or during neutrophil transmigration. Following secretion tethered to the cell membrane by CD177.
Protein: RUVB_HYPNA
Sequence: MSREGALSDPNAQGGDALDRALRPQTFEDYVGQRKAKANLKVYVEAARGRKEALDHVLLFGPPGLGKTTLAQILAREMGVGFRATSGPVIAKAGDLAAILTNLEPNDVLFIDEIHRLPAIVEEILYPAMEDYALDLVIGEGPAARSVRLDLAPFTLVGATTRAGLLATPLRDRFGIPVRLEFYEPEELGRIVMAAARKLGVPITEDGAVEISARARGTPRIALRLLRRVRDFAEAEGADINRASAARALKRLEIDEDGLDALDRRYLHALVKTYAGGPVGADTLAAALSEARDAVEDVIEPYLMQKGYVARTPRGRVAAPLAYERLGLKAPNGQQSALFGEDED
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.