Protein: NEC1_MAGO7
Sequence: MFLKQQQQQPVEADFVDCQSTPRAGGPVAGTTFYTVPVRTFGVELGEYWYPGGSRGPVAFVETEKLATFPTRFCASDYAGSSHSSPQPTAVGVSRERLDRGRFLGKHGEMPTLPLDSIASCGVHRIPEYRWIGKWAEQVDDGASAVNIRRLFEASSPIIGLDARFPGDGDTAERFYDFLLAGRSARSEIPPERYNADAFWHPDGNRSGATRARAAHFLKGSISAFDAPLFSITPTEAAAMDPQQRGILESVYRALENGKFPLAVVGGCNLIISPEFALLLDAAGVLGPDGKSYSFDHRGNGYSRGEGFGVVVLKRLPDALRDGDVIRAVIRNSGSNSDGRSPGITQPTKAAQAALIKQVYANAGLDPSVTRFFEAHGTGTAVGDPIEASAIAEVFATHRSHKSPLWVGALKSNIGHLEGAAGVAAVIKGVLTLENGVIPPNTWFERKNPKILDSWNLQFPTEPVVWPQTGLRRMSINSFGVGGSNAHVVMDDALHFLQSYGLVGNHRTVALPRLPGSSSSRRVVSQADSGVEFTDSDSELKTPDGTHSPDSTAEHSKDMNFDSSCTNTDTLQTTDTNKQPKLSAIACPEVLSSSLSRLAVSDEEGRQSQIFVFSSSDKDGVSRVVNELADYLAKKAKQYKPNMRDQSKFLRDLSYTLACKRTRHAWRSFVVAKTQSSLSALLQAKSLATRAASEPQLAFVFTGQGAQWPTMGRGLMAYPTFRESLHEAEEYMTQTLRCPWSLTYELCKEAGASRINDAEFSQPVCTALQVALVDLLRTWKVRPHAVVGHSSGEIAAAYAAGQLSRQSSWRIAYYRGKLATKLIRSLRRRENSQDAHVKKTGMVAVGLDKEQTLAAISRVDSLVGEGSLEIACMNSQESHTVSGDMAKLDALVEVLKSENVFARKLSVGIGYHSRHMLPIADEYVRLIGDIGSDLPPSQGQSLPRYFSSLEGSEITLDRLQSPDYWANNLTSPVRFHEAVELMLRADLGCNSQGESSTVGKKTVTDLLEIGPHAALRGPIRSIVKQVHQTAEWKIGYATVLKRGDGAIENALGAAGSLFCRGFDVDLAAVNQHQVESSRQSIALNGGNNVLMLTDLPGYPFNHKKEYWAESRLSRNYRFRSAPRHELLGAPVPDWDKNDAVWRNYIRITENPWVEHHKVSGEILYPAAGMLVMAIEASRQLVDKDQQVAGFRFKDVSFHLALLIPTNDVGVETRFRLRSVSAGKLAGWSEFQLSTSENDDWKEHCRGFVRTEYSQTGSNTESDSSRLVHSQCEQEIVQAKKSCTSMVHADKVYRKLSNIGLDFGTTFRTLKDVKFDGTSRILARAESQVSHIKKSMPAEYLHSHLVHPSMLDAVLQANLIPIALGSSSRDSLVPVFASDFWVSAATKEGVDFHNSAYLISSHAKLTPGTADAEAALFGIHADTGEPLVTSSGLVFKTIPNTASSGQRNHHRPALNLDWKPDPNYLTEEDALRMFGAPAITQSSDEVSDDIGDCEILCLLYIRRFLASLDDTVVEKLDWHHLRYVSWMRHVVQTTTVKPAVDNISVMEARIAAAGTPEGKLIMAVGRNLANILVTGDVDPLDVIFGDKVAENVYREGLGSRRCYAQMCAYLDALAHVNPSMKILEVGGGTGGATGSIMETLMANGARRFDHYDFTDISPSFFEHAKEAFKQTAEHMSFRVLNIEKEPTDQGYDGQSYNLVLAANVLHATKSMERTLANVRKLLKPGGKLIVFELTNPAVLLGGFCFGVLPGWWLSDEADREWGPLMVVDTWRAYLERAGFSGVDAVFDDFPDAAHQTSSILVSTALPVADASKPVTAVDNLTRYCVLMGERPSVFQRQVADALLPALARTGSVETSTITASAGRDLKGSCCIVLSELDSPTLIDMTTDVFVALQGVLNSCRRIIWLSRSGDDIVAAPDRELVTGLARVVRAEREPPFSFVTVSFAEAERSETIVDKTLQVLDRGQETAENSFRVFNGVVHVPRLVEAGYLTDHISAEANPTSTQATTQEVKLGADPRDFVAQVQSTGLLQGAGTADVCFSEDHSRQQPLADDEVEFKVMACGVGAHDVAAEDSAAGESSLSDMGIQMAGFVTRLGSTAASKFSVGDRVTGISLEGAIKTRARTQAGLLAKISDKLAWNQAAQIPMAYFTACAIIQYMGVGDSDDILLVHRAAASAAGLAAVQVARSNGAKIFATVANAQERTALQGVGGLLTDQILDLDQNTTLSTIVKSKTGNRGVSMIIDSLPQSDVDHAASLVDCLAPFGRFVSLGDGPMPGISSRRNICLERFNGAELMALDYEKAQRIFLRAARFILDEPLAANAQVPVYKFSEVSEAFAQLGKGEDAVVLEPHDEDVVKVVTSQQSHTDFTSRFDPGASYMVVGGLGGLGRSVSRWMASKGAKSLVLVSRKGAVTPEAQVLVAELQDLGVKVTTPACDATDKMALRRALDQCVAHMPPIKGVIQCSMVLKDKRFFEMSLEEWNTAIRPKVDVSVNLHDALDTASLDFFIMLSSTVGLTGSVEQANYAAGGTFQDAFARSLAASQTASSGPVAVSLDLPVILDVGFVAEKPELMDQLRAAGWAYMEEEEFHAALGYHCFQRRQLDLPTSVLRAQVAPRLWLAQDTADEGTEPPAWVRDPLFSHLRPQSSETTGNGAAGGEAGKKEMKHTALLAAATSAAEAQAVVLDALLAKLSRVLSVELSDLDPACPLSRYGVDSLVAVSLRAWIGKELGAELSVFEMTDKPSIRALAAAVAGRSRLVSKALS
What is the function of this protein?
Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of nectriapyrone and its analogs phomopyrone A, acropyrone and zaepyrone (PubMed:30443971).  The nectriapyrone biosynthetic gene cluster consists of two genes, the highly reducing polyketide synthase NEC1 that produces a demethylated analog of nectriapyrone from one unit of acetyl-CoA and one unit of malonyl-CoA; and the O-methyltransferase NEC2 that further methylates the NEC1 product to yield nectriapyrone (PubMed:30443971).  Nectriapyrone is further hydrolyzed to nectriapyrone D, also known as gulypyrone B, by an unidentified hydrolase localized outside the nectriapyrone cluster (PubMed:30443971).
What are the official names of this protein?
Highly reducing polyketide synthase NEC1, Nectriapyrone biosynthesis cluster protein 1.