Protein: CHYA_PENRW
Sequence: MAAPSISPLFAPQMGVQRDFQDSEMQIATVNFPCTGQSNTSLANWLQQEEKSHLQLLQAAWSISLRSYTGSNDVLFSCLNTKDTAALGANSVVYVDEGNEDKYGSARRGNLREFDLAICFSKQNEANCPVIGIHHKPSVISTDFATMIAATVAKAIEEIVLHVDSLIASLDICSDADINCISRWNSPSDDGIPSAQCIHHIISQKCATQPESIAVSAWDGRLTYAELDGLSSSLAIRLQHLGVCQEIFVPLIFDKSKWAVIALLSVLKAGGAYFFLNPSNPIQYNLGLCSSLSPEVALCSPRHSTLAKSFAGTAIPVGEEHCELPESLPVDEKTPPCTAETTPSNAMYITFTSGTTGVPKGITTEHSAFYSMAMANGKALQVGPATRMLQFASYTFDVSNRDMLITLMFGGCICIPSELDRLNDLSGFINRQSVNLASLTPSLASTLNPALCPSLQGLVLGGESMNDSHISAWANHVRLFNAYGVSESAGIAALASDIQADYSPGNIGFGSGSTLWVVTIDQPDKLAPIGALGEMVIEGPSVARGYLGDKKRTEEQFTSTSKWKNRIRAQLSESRSSKRAFHTGDLVRYNLDGSLNFLGRKDHQVKIHGQRLELTAIEHHIAACLEVAESGFLHVAVVTAKNEGNGSVKLLAFLGLYTSRGSDSPSQLVSKKLEDVEALKVALRQHLLLCLPAFMVPVDFIFVQHMPLTTSGKINRLLLQEAAGHALLDDQKRNIDTSDLNGNQTPTTQNQRILIQSWAKALGIKSESIMRNDCFFRRGGDSIAAIKMAASLRQQELIISVSDVFKFSTFSDMASVLVKDHRPLQTAMLAPFSLIDNSQTVLDAVMEELGTGIDQIEDVYPCTHMQQGLIALTAQQPHSYIGRYTWQLAEMLDVEKFKNAWESAWLHNPILRTRIVQIPDGVFQVVVKTDMPWNTVTDISRGGDGKELREIDISNGPLIQFYLSKESFRLDIHHSLFDEWSLGLIMGQVERAYAGGGLRMQPFSPFVQHLLHERDTSLEDFWRQEFSGLQAEHFPAIASRPLSVEHPTEKVVLEHSVQLETGFSTKYTISSIVRLAWAIVLWHQTGSEDVVFGATVSGRNANIDGIDQLSGPTLATLPVRIKLAASQPIHEGLSQVQGQFVNMMVHEQAGLPRIRQVGREAAEACNFQNLLVVQPYEEQTESHMFKASANSASSSENAKSFASYPMVLICRPEKSGISMKAAFDPAILTPAAGHSILKQMSHVIQQLVTSDSTCIAAVSLVPPEDMATLRQWNHSLPNGVNTCIHARIQELCIGQPDTLAIHSQNLDLTYGQLDNYSDQFAQNLIGSGVKQGDFVPLFLERSPWVPVIMLAVLKTGAAFVLLDLSHPMQRLRTMCSMIDARIVVTSKEHADRSGNLLLPVIIFDPEAHAQNVSKQATAPELKPLTAVTTPDAPACVVFSSGSTGLPKGIVLPHSALTTSAAVMREYGMLGPKSRVFHFASFAFDISIGEILFTLAAGACVCVPHEEERKGNPAKAAGDLKVTWALLTPSVINLFDPSDVPTLEVLGSAGEPLTPQIVDTWAHRVKLYGMYAPAECTVISHIGRILPDTHHSNIGKSHGGVSWVVDPSDHNRLVPIGTVGELIVEGPTVSSGYLNDPAKTNEVFITSPSWLDEVRSHSGKMYKTGDLVRQTSEGSLEFVGRKDDQVKLHGQRLEVGEVEHCITSSCTAIKTATVECIKIREQNSRVSLVAFICPQTDEDWGQSLNDPSSEVGDLELISPPRDQFYSMIESLETSLRELLPAYMVPSFFVPLADVPLSLSGKVNRRLLRDQSTSWPMKRLGLYQLRRKSIPAEEVPVSIHGRKVQEIVGQALNLDPKSIPMNSNFFGLGGDSISAMQVSMLARRRGIRLTVADIFTQQTLSGLSLKCATENGDASQASKSRSLGRELPGSNIKSLHRCEIPRDKLPRQLPQEIADNIVEAMPATEFQTMTLHNFYSRYLWISLPERVNQEHLLNACDQLVQKHSVLRTVFYTNDDKSVVQLTLRKVPVNFVHYSNIENLEKHCADDSLAMGVPINSVPGFEVQLVTLRDSGMYLILRLPHAQFDGVSLDIICSDLSAAYSGDSLPPCAQFSDHIRHVWEKRIPESYNAWREVLGNVPMTSLNNKYLRNWGSASEMGSPNMGTDPDQPKVVTAMAETLPISPPPNITLATLVKLAWAITLSRLFTSIEEDDGASDDVVFGQVVHGRGLGISHEDRIVGPCLNIIPVRVHLPPRSNKLDLLGQVQQQHIQTMSVENLELGEITRNCTSWKAGTKFGSFIRFQNFTNNDDSTCSFDGSACETGLYSLPNRPSNTANVLVVPHGPTLSITMTISNQVLDRGSADFVAGYFSDVIESLASEETVCEYLE
What is the function of this protein?
Nonribosomal peptide synthase; part of the gene cluster that mediates the biosynthesis of the yellow pigment chrysogine (PubMed:29196288).  the NRPS chyA mediates the condensation of anthranilic acid and alanine into the intermediate 2-(2-aminopropanamido)benzoic acid (PubMed:29196288).  The remainder of the pathway is highly branched yielding at least 13 chrysogine-related compounds (PubMed:29196288).  The malonyl transferase chyE converts 2-(2-aminopropanamido)benzoic acid and 2-(2-aminopropanamido)benzamidine into 2-(2-(2-carboxyacetamido)propanamido)benzoic acid and 3-((1-((2-carbamoylphenyl)amino)-1-oxopropan-2-yl)amino)-3-oxopropanoic acid, respectively (PubMed:29196288).  ChyD is an amidase, being responsible for the amidation of the carboxylic acid moiety of 2-(2-aminopropanamido)benzoic acid, 2-(2-(2-carboxyacetamido)propanamido)benzoic acid and 2-(2-((4-amino-1-carboxy-4-oxobutyl)amino)propanamido)benzoic acid (PubMed:29196288).  ChyC is involved in the same reactions as ChyD, but plays a more minor role in the amidation reactions compared to chyD (PubMed:29196288).  The oxidoreductases chyH and chyM are involved in oxidation reactions that form N-pyruvoylanthranilamide from 2-(2-aminopropanamido)benzamidine and (1-((2-carbamoylphenyl)amino)-1-oxopropan-2-yl)glutamine, respectively (PubMed:29196288).  N-pyruvoylanthranilamide is further converted via two further branches in the pathway, yielding chrysogine and additional chrysogine-related coumpounds (PubMed:29196288).  Chrysogine is likely formed by a spontaneous ring closure from N-pyruvoylanthranilamide (PubMed:29196288).
What are the official names of this protein?
Nonribosomal peptide synthase chyA, NRPS chyA, Chrysogine biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.