PharMolix/UniProtQA huggingface dataset:
Protein: RNJ_MYCS2
Sequence: MSAELAPPPPLAPGGLRVTALGGISEIGRNMTVFEHLGRLLIVDCGVLFPGHDEPGVDLILPDLRHIEDRLDEIEALVVTHAHEDHIGAIPFLLKLRPDIPVVGSKFTIALVREKCREHRLKPKFVEVAERQSSQHGVFECEYFAVNHSIPGCLAVAIHTGAGTVLHTGDIKLDQLPLDGRPTDLPGMSRLGDAGVDLFLCDSTNSEHPGVSPSESEVGPTLHRLIRGAEGRVIVACFASNVDRVQQIIDAAVALGRRVSFVGRSMVRNMGIARELGYLKVDDSDILDIAAAEMMPPDRVVLITTGTQGEPMAALSRMSRGEHRSITLTSGDLIILSSSLIPGNEEAVYGVIDSLSKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRNVMPVHGTWRHLRANAALAASTGVPPENIVLAENGVSVDLVAGRASISGAVTVGKMFVDGLITGDVGDATLGERLILSSGFVSITVVVHRGTGRPAGPAHLISRGFSEDPKALEPVAQKVERELEALAADNVTDPTRIAQAVRRTVGKWVGETYRRQPMIVPTVIEI
What is the function of this protein?
An RNase that has endonuclease and 5'-3' exonuclease activity.  The 5'-exonuclease activity acts on 5'-monophosphate but not 5'-triphosphate ends.  Endonuclease activity can cleave within 4 nucleotides of the 5'-end of a triphosphorylated RNA.  Plays the major role in pre-23S rRNA maturation, and a minor role in processing of pre-5S and pre-16S rRNA.
What are the official names of this protein?
Ribonuclease J, RNase J.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_GLOVI
Sequence: MKVDRKTATHRRHQRIRRKIAGTPEQPRLAVYRSNRHIYAQVIDDVHQRTLVAASTLEAPLRSGEEGTATCEAATAVGRLVAERAKEKGITAVVFDRGGKLYHGRVKAVADAAREAGLDF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ISPG_AROAE
Sequence: MATNSSSGSLVRHKTRQVRVGRISIGSNAPVVVQSMTNTDTVDVLGTAMQVAELARAGSELVRITVNNEAAAKAVPHIRDRLLALNVDVPLVGDFHYNGHKLLSEHPACAEALAKLRINPGNVGAGAKRDPQFAAIVDIACRHDKPVRIGVNWGSLDPSVLARVMDQNAKLAQPRDANAVMREALVVSALESAAKAEEYGLGGDRIILSAKVSSVQDLIAVYRDLAARCDYPLHLGLTEAGMGSKGIVASTAALAVLLQEGIGDTIRISLTPEPNGSRAQEVVVAQEILQTMGLRAFTPMVIACPGCGRTTSTFFQELASGIQSYVRDQMPVWREQYDGVENMTVAVMGCVVNGPGESKHANIGISLPGTGETPAAPVFVDGEKTVTLRGDNIGTEFKAIVDDYVATRYVKKAG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: FLGG_RHIME
Sequence: MKALSIAATGMNAQQLNLEVIANNIANINTTGYKRARAEFSDLLYQTERAQGVPNRSNQAIVPEGAIIGLGVQTSAVRNLHIQGSLVNTGNDYDLALVGRGWFQIETPDGETVYTRSGAFNTNATGQLVTIDGYTVVPGVTVPQDATEIVFTSSGQVMVRIGNDTELQEIGQLTIANFVNEAGLEPMGENLFRQTPASGDPIVGTPADPGFAQVKQNYLESSNVDPVKEITDLISAQRAYEMNSKIIQAADEMAATVSKNLR
What are the official names of this protein?
Flagellar basal-body rod protein FlgG, Distal rod protein.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: GCS2_ESCF3
Sequence: MPMPDFQVSEPFTLGIELEMQVVNPPGYDLSQDSSTLIDAVKNQITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFETLFRCLSYTKMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSADKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: RL3_CHLL2
Sequence: MGAILGKKIGMTRLYNDKREAISCTVIQAGPCFVTQVKSAEKDGYDAYQIGIGERDEKKINKPMQGHYRKAGVTPGFMMAEFKKTEFSENLEAGNPVSVESFKEGEKVNVLGVSKGKGFAGVVKRHNFGGGSRTHGQSDRLRAPGSVGGSSDPSRTFRGTRMAGRMGGDNITVKNLEIVKIMPESNLLVIKGAVPGPKNSYVKIVSIKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RLME_HALHL
Sequence: MATCRRRRRGCNSQARRSRHESDPFVRRARAEGWRSRAALKLEAIDQRDGLFRPGQVVVDLGAAPGGWSQLVAPKVGSAGRVVAIDLLEMDPLPGVTFLHADFSTDEGLRAVERALEGRPVDIVLSDMAPNLTGHNAVDQPAAMGLAELAADFAGQFLHKNGDFLVKVFHGEGFDAFRGDLTRRFSRVLSRKPDASRSGSREVYLLARGPTV
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US03_GAHVM
Sequence: MSSSPEAETMECGISSSKVHDSKTNTTYGIIHNSINGTDTTLFDTFPDSTDNAEVTGDVDDVKTESSPESQSEDLSPFGNDGNESPETVTDIDAVSAVRMQYNIVSSLSPGSEGYIYVCTKRGDNTKRKVIVKAVTGGKTLGSEIDILKKMSHRSIIRLVHAYRWKSTVCMVMPKYKCDLFTYIDIMGPLPLNQIITIERGLLGALAYIHEKGIIHRDVKTENIFLDKPENVVLGDFGAACKLDEHTDKPKCYGWSGTLETNSPELLALDPYCTKTDIWSAGLVLFEMSVKNITFFGKQVNGSGSQLRSIIRCLQVHPLEFPQNNSTNLCKHFKQYAIQLRHPYAIPQIIRKSGMTMDLEYAIAKMLTFDQEFRPSAQDILMLPLFTKEPADALYTITAAHM
What is the function of this protein?
Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and inhibition of apoptosis.  Phosphorylates UL31 and UL34 homologs, two critical regulators of capsid budding from nucleus to endoplasmic reticulum, thereby facilitating virion egress.  Modulates and redistributes host components of the nuclear envelope, including LMNA, emerin/EMD and the nuclear matrix protein MATR3.  Phosphorylates envelope glycoprotein B (gB), probably to direct it to the cell surface.  Promotes virus intracellular spread by restructuring host cell cytoskeleton.  Blocks host apoptosis to extend cell survival and allow efficient viral replication.  Promotes viral gene expression by phosphorylating host HDAC2 to reduce viral genome silencing (By similarity).
What are the official names of this protein?
Protein kinase US3 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: SDA1_DICDI
Sequence: MGTRILDLLQLQNLTKRDPSAYKEEFLLQYQHYLTQLQIFQLKPTKEFKHFSQLVSYLSHVCVCYPKELSEFPKQISDLLENNCNNLEPELRRILAKSLILMRNRNLLPQIQMLSLFFKLFRVHDKPLRSLLYSHIVADIKNTNLKQKNQKLNRTLQNFMFTMMNDDSEIASKMSLKVMIELFRKKIWHDTKTVNVISNGVFSKNSKILITTLNFFLHIDNPDKPDEEEEDEAVKEKRAKDNFRKKSLAHRVGKKTKGRITRLAKSKVDLKKAKQEEDNKLQPNFPAIELIHDPQGYCDKLFNVLVKTTEKFETRIMIMNFISRLIYVHKLMVYNFYPFLQKYLQPHQKNITYLLAVLAQSCHELVDPDVLKPLVMTIAKYFVNDGCGSDVIAIGLNTIRSICSRCPLAIDTVLLADLIQYREKKEKGVAMASKSLLQFFKDNYPSMLPKKERGKNKTDIGLLAFGHQKVSQGIDGLDLLMDEELNARLDAIEAGEEFESDDDSDSDSDDEGWEDVNTTTADDDNNSEWVSDDDDEEGEEDEEVEDEEDEEEVDEEELEDDEEGDWESGEEIEGDDDDDEEWEEVEEEVEEEEEEEIKPTKKKSQQKEKVEVLRTDDIKVLTDEELIRIRKLRILKEARENNKQYEDMDQDDDENGENVHGLIRPEDLQGAHKKKKEEKLERIARAKEGRDGGYGSKASRRDKTGKSTTNEYKAKVTKPFVLTLKTKKVRGKSLKSFRDKQIGQREHSARQKRGRH
What is the function of this protein?
Required for 60S pre-ribosomal subunits export to the cytoplasm.
What are the official names of this protein?
Protein SDA1 homolog, SDA1 domain-containing protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SDA1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HSLU_STACT
Sequence: MDASAIKLTPKDIVSQLNEYIVGQNDAKKKVAIALRNRYRRSQLDEEMKQEIVPKNILMIGPTGVGKTEIARRMAKIVGAPFIKVEATKFTEVGYVGRDVESMVRDLVDVAVRLVKEDRKDKVKDEAVKKANDKLVKLLVPSMKKKANQNAGNPFESIFGGMMPNFGNNDEEDEEPPTEDIKTKRSEIRSQLLNGQLEEEKVRIKVEQDPGALGMLGTNQNQQVQDMMNQLMPKKKVEREVPVKTARKILADEYADELIDHETANQEALELAEQMGIIFIDEIDKVASNNQGGGQDVSRQGVQRDILPIVEGSVVQTKYGSVNTEHMLFIGAGAFHVSKPSDLIPELQGRFPIRVELDSLSVDDFVNILKEPKLSLIKQYEALLQTEEVTVNFTDEAITRLAEIAYQVNQDTDNIGARRLHTILEKMLEDLSYEAPGMPNAVVDITAQYVDDKLKSISTNKDLSAFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_CUPNH
Sequence: MPLNIEDKKAVVAEVSAQVAKAQTIVVAEYRGITVGDLTKLRSTARQQGVYLRVLKNTLARRAVEGTPFASLAEQMTGPLIYGISEDAVSSAKVLNDFAKTNDKLVLRAGSYDGKVLDAAAVKALASIPSRDELIAQLLGVMQAPVSGFARLLAALAAKNAEGAPAEAEAAGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: APT_BORBZ
Sequence: MKNKTEYYDQFISKIPNFPKKGVLFYDITSVLLKPEVYSSLINEVYSFYNFKKIDCIAVVESRGYLIGAPLSLKMQLPLVLIRKEGKLPREVFSEEYELEYGFGRIEVHKDDVRMYSNILLIDDILATGGTLKSSAILLERAGGKVKDIFCFIELCAINGRQSLESYEVNSLVRYN
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_XANP2
Sequence: MELRLYNTLTRSKDTLRPLDPANVRMYVCGPTVYDHAHIGNARPVIVFDVLFRLLRRLYGEGHVKYVRNITDVDDKINARAAERGITIRDLTEETYRWFREDTAALNCLRPTVEPRATEHIAEMRTLIESLVASGHAYVAEEHVLFHVPSMPDYGRLSRRPLDEMVAGARVDVAPYKRDPMDFVLWKPSEAGIPGWPSPCGIATPGRPGWHIECSAMSWRHLGETFDIHGGGIDLVFPHHENEIAQSRCAFHTGVMAQMWMHNGFLMLEGEKMSKSLGNFVTIRELLAEWPGEVLRLAMLSTHYRQPINWTRQGLGFAAKTLDKWYRIIGEAEAETGEGNPFETEIADRLADDLNTPSVITHLHHLAEVAEHEEASSALRRRFKGAANLLGLLGDTETGWRARQKEAIALDEGVIAGLIADRLAARKAKDFKRADQIREELAAQGVVLMDNKDGTTSWEVSR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y548_METJA
Sequence: MSLIICYYGKNGAVIGGDRRQIFFRGSEENRKILEEKLYSGEIKSEEELYKLAEKLNIKIIIEDDREKVRKISDSVVCGEVRSLGIDAKRRRVYATKGKCAIVDILNDTVTNQTIKEGFGIVVLGNRFLKKKAEEELKRTAKLFPMMPIQQIEDAIKEIFEKLKWHPTVSKEYDIYSVNKYEKNFEEVIKKDIESLFKYREQLRKQLIDFGKVMSIVNKIVKNGEIGVIKDGKLHLYDDYIAIDKIDPNPKVFKVVDVEGNFKDGDIVVIENGDMKIKGTNEKVTTKYIIIHK
What are the official names of this protein?
Uncharacterized protein MJ0548.
Protein: RLMN_NITOC
Sequence: MTDSRTNLLNLDRAGLDAFFTCLGEKPFRARQVLRWIHQRFVTDFSAMTDLNKSLRERLTESAVISLPEIIKQHRSADGTHKWLLRMHGNNCIETVFIPEGDRGTLCISSQIGCILDCSFCATGKQGFNRNLAVSEIIGQLWLANKTLGRDPKGERIITNVVMMGMGEPLANFNNVVTAMNLMLDDFSYGLSWRRVTLSTAGMVPAMDRLRAVCPVNLAVSLHAPTDKLRDELVPLNKKYPLQDLLSACRRYVAGDRRRAVTFEYVMLAGVNDSLPHARALLRLLRGLPAKVNLIPFNPFSGSVYRRSDAATIDRFREELLRGGIMTVTRKTRGDDIAAACGQLAGRVQDRTRRTMDRQRLVSVLPRSPLAS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS8_PHYBI
Sequence: MAFLKKSLFLVLFLGLVSLSICEEEKRENEDEEEQEDDEQSEMKRGLWSKIKEAGKAALTAAGKAALGAVSDAVGEQ
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Dermaseptin-B8, DRS-B8, Dermaseptin-gene related 2, Dermaseptin DRG2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP23_PHANO
Sequence: MASSPSNPETAPDGASLAAMTTDQPKKIDPVYYNWSSTFSILLSRMTGSRDVPLEEKYFTEMDALKADTICQRCDSNRDYLLQYSPIVRFLKDEVEKLGGDLNKDNILCRMCTNSQSGGFSLDHGILLCANKFRNRGHQEDTMAHEMVHAWDHLKFKVENDNLRHQACLEIRASTLSGECRFSREFFTKNQWSVTEQLQRCVRRRATLSMMARPGVRDEKHAGEIVNQVWEGCFRDTRPFDEIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: 5055R_ASFM2
Sequence: MFTLQEICRKNIYFLPDWLNEHVAQRLGLYWEKHGSLQRIGDDYVLIQQDLIISINEALRMAGEEGNDEVVQLLLQWEGNIFYAIIGALEGDHDSLAYKLYSQIRDCHTILPLIQDPKIFEKCHDLDESCNISCLVLNAVKHDMLCILQEYKMLLSGGDIQEVFEIACRSLKYDIVTWMGQNIAIYNPGVIFDIAFDKMNVSLLSIGYTLLFNHHINHINHENIDVNSLLTQHLEWAAGMGLLHFMLETLKYGGDVTIIVLSAAVKYDHRKVLDYFLRRKNLYREDIEELLLLAISADCSKKTLNLLLSYLNYSIDNIRKKILQYVKEYETTLIIKILWKKKKINLIEPILADFIGYHSYTYMKGFMRDFSIHPERIIKMAARESREDLIIKFSKNVCKEPKDRLHYLKNLVYTMKHKGGKQLLIYTIHNLYKASCLESKEMFKLARFYARHDARIQFKSICHDLSKQNINIKNLLLECLGIAIKKNYFQLIETIEMTMNYE
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-5R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: EME1_ORYSJ
Sequence: MASHAAVVEIIDDDDDDDDDVAAASTPPALHKRSHAVAAAAPDSPDAFSPSPPDPKRRQLAASTIVLDDTPTPPKRRPPPVAADRSASVVADTPRSFVPCSLRNRAIAGDTPDSVLPSPSFHLDAPDSATPGSDVPCSVGLDDIVPETPGFNSPRLARPPAVPGLTSPMTARKFSGVSCPISLDSDDELDDTVYRESLTRTPSNMAKPEHAIQPCTTSCTDKVENTKSTDKKDYSKSNVGYQTNNSACKNNGTTSYNQPPRANSPCEDSTLKEADPFINNHCPQEENALPIEERKKKQQEEKRLKKEKKAREIEEKKQKRLETKKQKEAMKAELAELKKLEKEKKKWESGKLATKCIVAEIDSSVIESGSVGGHLVQGFHEKGLCFRVTSNSIKGSILWKMQIPNEFTQDQASTSQVPYILFVLQAEEFCDLVSGGTLLDHVQKVRRQYPEFTICYVTNKLMSFIKRREQNQYNKTTSNSNSWKRPPVEEALCKLATHYARVRSRHCTDEAEVTEHIVGLTYSLANCKFRKPLTWLSVHANGSNISKGCVDKDRIKKSAWLKSLVAIPGVSPGQAIAIEKKYPSMRSLLNVYMDDSKSVHEKEHLLEDLRLEGPLGDFKRRLGPACSKKVYTILMAQNGAAEVEVDRRGA
What is the function of this protein?
Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency.  May be required in mitosis for the processing of stalled or collapsed replication fork intermediates.  Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells.  Mediates a subset of meiotic recombination events that are insensitive to crossover interference (By similarity).
What are the official names of this protein?
Crossover junction endonuclease EME1, Essential meiotic endonuclease 1, OsEME1.
What is the protein family that this protein belongs to?
Belongs to the EME1/MMS4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRR_BACAC
Sequence: MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: Y4117_PSEPG
Sequence: MMIAENAPFWRRKTLEQLSPQEWEALCDGCGLCCLQKLEDEDDNSVYYTRIACKLLDLDSCQCSDYPNRFAQVPDCIQLTPGKADQFKWLPSTCGYRLVSEGKDLPAWHHLVCGDRQQVHEQRISQSGRMLREQDVHEDDWEDHLIFRAS
What are the official names of this protein?
UPF0260 protein PputGB1_4117.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: GLUQ_SYNSC
Sequence: MALPEHLQRHLEAGRALTAAGGYRGRFAPSPTGLLHLGNLQTALLSWLAARQAGGAWLLRIDDLDTPRNRAGAIEAIQSDLRWLGLKWDGPVLLQSERRGIYHSWLSWLRRSGRLFACRCSRRELADQPIYSGFCRQAVHNWGWQRQRLPSWRLRVADDDPHGSGDVVLRRADGFIAYQLATVIDELSFGINDVVRGADLREALPAQRSLFAALGEAPPRFRHGPLLCDASGQKLSKREACAGLKPLRDAGLDAAAVIGRLASGLQLVAPEARISATELLEHLTQQAINAVIS
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: KLEE1_ECOLX
Sequence: MSNIVKFPRASKPPAPEPVQPAAPAAAPAAPKAEGRGLVAGLVKFVWVATVLVWPVLKWVLAIITFFQFVRMLYHWNTPGVYAGWSFLAYFAALTAITYFVSIYKPKGL
What are the official names of this protein?
Protein KleE, KcrB3 protein.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPB_MYCTO
Sequence: MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDGIAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTAQQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVRGSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAMDAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDGDLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSAWTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADSLILG
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_THEVB
Sequence: MAVNDTIGDMLTRIRNANLARHQTTTIPATRMTRSIAQVLKAEGFIRDFEEQGDGVKRHLVVSLKYRGKQRQPIITALKRVSKPGLRVYANSRELPRVLGGIGIAIISTSNGIMTDREARKQGIGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GLMU_BACAA
Sequence: MSNRFAVILAAGKGTRMKSKLYKVLHPVCGKPMVQHVVDQVSQLGLQKLVTVVGHGAEMVQEQLGNVSEFALQAEQLGTAHAVDQAAGVLANEEGTTLVICGDTPLITAETMEALLQQHKEAGAMATVLTAYIEEPAGYGRIVRNENGHVEKIVEHKDANEKELAIKEINTGTYCFDNKALFASLSKVSNDNVQGEYYLPDVIEILKNEGHIVSAYQTEHFDETLGVNDRVALSQAEIIMKNRINRKNMVNGVTIIDPSNTYISADAIIGSDTVLHPGTIIEGNTVIGSDCEIGPHTVIRDSEIGDRTTIRQSTVHDSKLGTEVSVGPFAHIRPDSVIGDEVRVGNFVEIKKTVFGNRSKASHLSYIGDAQVGEDVNLGCGSITVNYDGKNKFKTVIGNGVFIGCNSNLVAPVTVEDGAYVAAGSTITENVPSKALSVARARQVNKEDYVDQLLNKKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P15LB_DANRE
Sequence: MADPAWWKLTFLKKKKSEAKVLYEIPPDFSNNNANKDLDHDAADSNLDARLEKIVATKSATKGRHVKVSHSGRFKEKKKIRATLVENPSLFPESAQTEKSHVEQ
What are the official names of this protein?
Proline-rich protein 15-like protein B, Protein ATAD4-B.
What is the protein family that this protein belongs to?
Belongs to the PRR15 family.
Protein: NTCP7_CHICK
Sequence: MGLLERLRKEWFIAGIALVIAAARLEPAVGVKGGPLKPEITITYIAVSAIFFNSGLSLKTEELTSALMHVKLHLFVQIFTLVFFPTAIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERRKPPFGTISSCVLLMIIYTTFCDTFANPNIDLDKFSLIIIVFIIFSVQMSFMFLTFLFSTRSNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGYEHLSLISVPLLIYHPAQILLGSLLVPTIKSWMVSRQKALKLTRQPKVPVKV
What is the function of this protein?
Involved in teeth and skeletal development.  Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix.  Required for extracellular matrix mineralization.  Also involved in the regulation of cellular calcium homeostasis.  Does not show transport activity towards bile acids or steroid sulfates.
What are the official names of this protein?
Sodium/bile acid cotransporter 7, Na(+)/bile acid cotransporter 7, Solute carrier family 10 member 7.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane.