PharMolix/UniProtQA huggingface dataset:
Protein: PRO_ADE12
Sequence: MGSSEQELTAIVRDLGCGPYFLGTFDKRFPGFVSRDRLSCAIVNTAGRETGGVHWLAFGWNPKSHTCYLFDPFGFSDQRLKQIYQFEYESLLRRSALAATKDRCVTLEKSTQTVQGPFSAACGLFCCMFLHAFTHWPDHPMDKNPTMDLLTGVPNCMLQSPQVVGTLQRNQNELYKFLNNLSPYFRHNRERIEKATSFTKMQNGLK
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: HSP70_MIMIV
Sequence: MSDKIAIGIDLGTTFSCVGVWQNGKVEIIANDQGNRTTPSYVSFTETEHLIGDAAKYQAAINPTNTIFDAKRLIGRDFNDQSVQSDMKYWPFKVINVGNKPYFEVSYQNESKQYSPEQISSMILSKMKQTASAYIGKEVTDAVITVPAYFNDSQRQATKDAGRIAGLNVLRIINEPTAAAFAYGLDKNQDKEMNVLIFDMGGGTHDVTLLSLEDGLFQVRATSGNTKLGGEDFDNRLVTWCVEDFKRKYKTDLNQSAKALRRLRTACERAKRALSSSTQTTIEVDSLFEGIDYNVTLTRAKFEELCSDLFRAGLEPVEKVLLDSKLDKSQVHEIVLVGGSSRIPKVRQLLSNFFNGKKLNETVNPDEAVAYGAAIQAAILVGQTDEKLQNIVLVDVTPLSLGLETAGGIMTNIIDRNTTIPCKKSRVFTTYSDNQTVVTIQIFEGERKFTKDNNNLGTFNLEGIPPAQRGVPQIEVTFDLDANGILNVTAADKSTNKSKNITITNNRGRFSEDQIERMIREAKEFEEADNKKKAAVDSKNELENYTHSVKQAVTDPSNSNNIEESSRSQIESKCAEIMKFVDENPNEDQGTYDLRRKELEDLWNPIAVTLYAQKNNQSNQTSTESTGPTVEEVD
What is the function of this protein?
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides.
What are the official names of this protein?
Heat shock 70 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CH10_HUMAN
Sequence: MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTKVVLDDKDYFLFRDGDILGKYVD
What is the function of this protein?
Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly.  Together with Hsp60, facilitates the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:7912672, PubMed:1346131, PubMed:11422376).  The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring.  In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10.  This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components.  Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).
What are the official names of this protein?
10 kDa heat shock protein, mitochondrial, Hsp10, 10 kDa chaperonin, Chaperonin 10, CPN10, Early-pregnancy factor, EPF.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: COAD_STRU0
Sequence: MSDKIGLYSGSFDPVTNGHMDIIARASQLFDHLYIGVFFNPEKKGFFDLETRINVLKEALVDYPNISVVSAADSLAVDLAKSLGVTHMVRGLRNPTDFEYESNLEFFNNRLDPSIDTIYFIAHNLMQPISSSRVKELIHFNSSIEGLVPQSVIKQLESMNESNQNL
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_XANC5
Sequence: MSQPPAAHVPVLYTQVLDGLQVTENGTYLDGTFGRGGHARGVLEHLGPGGRLLVMDKDPEAIAVAEHSFGGDARVSIHRGSFAGLGQVVAAATVDGILLDLGVSSPQLDVAGRGFSFGKDGPLDMRMDPDNGQSAAQWLAQASEREIADVLWTYGEERQSRRIARAIVARRAEQPLLRTAQLADLIASVMPRGDSKTHPATRSFQAIRIHINRELADLEAGLDAALDALKPGGRLAVISFHSLEDRIVKQFMARYAKAPPSNRRLPEAQPFVPTLQLVSGAIKADDAELNVNPRARSAVLRVAEKLGVGIRNSGLEERSKRIPNPQSPIPASQGDAQ
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBL1_ARATH
Sequence: MGFFLCSSSSIFFKFGISIIFLVSFSGLTPSEAYDPLDPSGNITVKWDIITWTGDGYVATVTVYNFQQYRHIQAPGWTLGWSWAKREVIWGMNGGQTTEQGDCSKFKGTIPHCCKKTPSVVDLLPGSPYNQQIANCCRGGVLNSWAQDPATAVSAFQLTVGQAGTTNKTVRVPKNFTLKAPGPGYTCSPAKIVKPTRFIGTDKRRVTQALMTWNVTCTYSQFLAQKTPTCCVSLSSFYNKTIVSCPTCSCGCRNTSQPGNCVDPKGPRIASVIPNPGKNAYIPPLVQCTKHMCPVRIHWHVKVNYKQYWRVKVTITNFNYNMNYSQWNLVVQHPNFDNLTQTFSFNYKPLTPYASINDTGILWGIKFYNDLLMQAGPFGNVQSELLFQKEASAFTFEKGWAFPRRIYFNGDNCVMPPPDSYPWLPNTGSHKSVGSLFAAMALLLIVFLHGNL
What are the official names of this protein?
COBRA-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the COBRA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: LARIA_RHOJO
Sequence: MTSQPSKKTYNAPSLVQRGKFARTTAGSQLVYREWVGHSNVIKPGP
What is the function of this protein?
Peptide antibiotic with selective activity against Mycobacterium species (M. smegmatis, MIC=6. 25 ug/ml).
What are the official names of this protein?
Lariatin, Class II lasso peptide, Lariat peptide, Ribosomally synthesized and post-translationally modified peptide, RiPP.
Protein: RAD10_YEAST
Sequence: MNNTDPTSFESILAGVAKLRKEKSGADTTGSQSLEIDASKLQQQEPQTSRRINSNQVINAFNQQKPEEWTDSKATDDYNRKRPFRSTRPGKTVLVNTTQKENPLLNHLKSTNWRYVSSTGINMIYYDYLVRGRSVLFLTLTYHKLYVDYISRRMQPLSRNENNILIFIVDDNNSEDTLNDITKLCMFNGFTLLLAFNFEQAAKYIEYLNL
What is the function of this protein?
Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.  Along with RAD1 forms an endonuclease that specifically degrades single-stranded DNA.
What are the official names of this protein?
DNA repair protein RAD10.
What is the protein family that this protein belongs to?
Belongs to the ERCC1/RAD10/SWI10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COX2_THETH
Sequence: AYTLATHTAGVIPAGKLERVDPTTVRQEGPWADPAQAVVQTGPNQYTVYVLAFAFGYQPNPIEVPQGAEIVFKITSPDVIHGFHVEGTNINVEVLPGEVSTVRYTFKRPGEYRIICNQYCGLGHQNMFGTIVVKE
What is the function of this protein?
Subunits I and II form the functional core of the enzyme complex.  Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c ba(3) subunit II, Cytochrome c oxidase polypeptide II, Cytochrome cba3 subunit 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MUTS_ORITB
Sequence: MLTKEDFRNKYQYHQATPMLQQYLDIKFTHQCCILLFRVGDFYELFFDDAIVVSKLLGLILAKKGKHAGQDLPMCGIPYHALESYLPRLVEQEHKVALCEQLESPEEAKKRNGYKAVVKREVVRIITSGTITEESLIKANVPNYLAAIVIHKDIASIGYCDVSTAEFIVIDVAIHNLTSELSRINPKEIILSESLQHNSGLLALFDNYKQKIVYQVESYFSFNKAQRVIQNYYEIITIDSIGSLNSTQVSAVGAILEYLSIMQKHSKSKLPFPQIVSYENFMLIDASARKNLELTSTLSGNFKGSLLSIIDATVTNQGGRLLHKFLSTPLAEVNLINSRLQITDFFYQNLQLVENLRQLVKLVPDIERALSRILIAKALPKDLESIKISLKIALSIKKELNKVLEEGNTPKYLEEIYNPLFGDNELYELLDSALLDDLSNSANDCGFIKSSYSTKLEELRNLIHNSSNFIEQLKLQYRQETCIETLKICHNNVWGMFIEVSSKNAHKITDSKFVHKQTTTTAVRFTTTELQTLEAKMLNAKTMAAALEQEILAELCKAISLKSEKLSHLAKSISLIDVFCNFAYISHEYNYCRPEITSDLAFNIVDGRHAVIEKLITKKHESFISNDCNLQNDQRIWLITGPNMAGKSTFLRQNAIIVILAQIGCYVPAQSAQIGVVDKLFSRIGAADDLASGQSTFMVEMVETSVILAQSTFMSLVILDEIGRGTSTYDGISIAWSCLEYIHSNIRCRCLFATHYHELVDLASKLLSLKNFTVKIHDSNDKLSFLYKIIEGAANKSYGIHVAELAGLPRIVLNRAKEILLELEHNKVNINQSNNNITKSIDIAVPPYPVKTIEIIKQLNPDQLTPKEALSIIYKIKNTILLEEDEKMI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: TILS_EDWI9
Sequence: MNTLDIQRHIADRLAGRRRLLVAFSGGLDSTVLLHALVQLRASCLPHLRLRVVHVHHGLSHFADQWVDHCESVCYLWQVPLHVLHVQVDTQRNSVEAAARDARYQAIAELIDSRETLLTAQHLDDQCETFLLALKRGSGPTGLSAMAQSMPFFVCEQLRPLLDISREQLTAYAQVHDLSWVEDDSNADARFDRNFLRMRIVPLLRERWPHFSEAVARSASLCAEQEQLLDELLMESLQALMSEDDALSIDGLLPLSEAKRYALLRRWIACFGVMMPTREQLQRLWHEVALAREDAEPQLHLAKCQVRRFRRRLYLLPTLRSLRDEVLRWDPHQPLTLPDGLGELQMGSRGVCVRAPTPGEAVTIRFCAQGVLRIVGRRHSRAIKKIWQELHIPPWERERTPMLYYGESLIAALGVFVTQEGQAVAGATMWNIHWSKDWM
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADA_PLAGA
Sequence: MTILHEEINFLKKDELNINLKCLDKKERYKIWRRIPKCELHCHLDLCFSLEFFLKCVRKYNLQPDLTDDEVVDYYLFKDKGKSLNEFIERSRRVTDIFINYDIIKDIAKNAVFNKYKEGVILIEFRYSPSYIAYKYNLCIDLIHKTIVEGINEAVEKLNHKIHVGLICIGETGISEESLRKAAEFCVKNKKDFVGFDHAGHERDLKPYKEIYDYVRENGIPLTIHAGEDLTLPNLNTIYSAIEVLKAKRIGHGIRVIESEDLINLIKKNDILLEICPISNLLLNNVKSMDTHPIKKLYDSGIKVSVNTDDPGMFLTEINDEYEELYLNLNFNLEDFMKMNLWALEKSFVKSEIKDKLKKLYF
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine to produce inosine (PubMed:19728741).  Unlike other Plasmodium adenosine deaminases, does not catalyze the deamination of 5'-methylthioadenosine (MTA) (PubMed:19728741).  Plays an essential role in the purine salvage pathway which allows the parasite to use host cell purines for the synthesis of nucleic acids (Probable).
What are the official names of this protein?
Adenosine deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: LYG2_HUMAN
Sequence: MLSSVVFWGLIALIGTSRGSYPFSHSMKPHLHPRLYHGCYGDIMTMKTSGATCDANSVMNCGIRGSEMFAEMDLRAIKPYQTLIKEVGQRHCVDPAVIAAIISRESHGGSVLQDGWDHRGLKFGLMQLDKQTYHPVGAWDSKEHLSQATGILTERIKAIQKKFPTWSVAQHLKGGLSAFKSGIEAIATPSDIDNDFVNDIIARAKFYKRQSF
What is the function of this protein?
May act as a potent antibacterial protein that may play a role in the innate immunity.
What are the official names of this protein?
Lysozyme g-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 23 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR8_POPTR
Sequence: MGRDTLADIITSIRNADMDRKGTVRIPSTNITENIIKILLREGFIENVRKHQEGNFFFFALTLRHRRNRKGPCRTSLNLKRISRPGLRIYSNYQQIPRILGGMGIVILSTSRGIMTDREARLERIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1580_BACVZ
Sequence: MSLEKTTRMNYLFDFYQSLLTSKQKSYMSLYYLDDFSLGEIAEEYDVSRQAVYDNIKRTEAMLEQYEEKLLLFKKFQERKEMFTKLKELASGLQEEEKMTALIEALEKLD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein RBAM_015800.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: CNU_SHIFL
Sequence: MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAADHRRAELVSGGRLFDLGQVPKSVWHYVQ
What is the function of this protein?
Modifies the set of genes regulated by H-NS; Hha and cnu (YdgT) increase the number of genes bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex on DNA.  The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC.
What are the official names of this protein?
OriC-binding nucleoid-associated protein, H-NS/StpA-binding protein 2, Transcription modulator YdgT.
What is the protein family that this protein belongs to?
Belongs to the Hha/YmoA/Cnu family.
Protein: HOG1_HORWE
Sequence: MAEFVRAQIFGTTFEITSRYTDLQPVGMGAFGLVCSAKDQLTSQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIICLSDIFISPLEDMYVVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIATICSENTLRFVQSLPKRERQPLKNKFKNADPQAIELLERMLVFDPRKRVKAGEALADPYLAPYHDPTDEPEAQEKFDWSFNDADLPVDTWKIMMYSEILDFHNVDANAEQAAHNNDTVAG
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes.
What are the official names of this protein?
Mitogen-activated protein kinase HOG1, MAP kinase HOG1, HwHog1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic in unstressed cells but rapidly concentrates within the nucleus in response to hyperosmotic conditions and phosphorylation.
Protein: RETIN_DROME
Sequence: MSRLFLPVLAIVLVSIGASHTASLEWPSNLVALSSVKSSQLLPIASEDSVELADGSSGSVSSSAAQPEDQSQEEAEEQQVSSASSGSADPISGRLVSAGIPVSVPLPLILAARNGLRTVLTIQEPAVAKVGEVVQHVPTAVSHQTQTVVHDHRRLVTPIVAPAVRTTQVIRQQPPLLWSVASDPRVVLIRN
What are the official names of this protein?
Retinin.
What are the subcellular locations of this protein?
Secreted.
Protein: D9043_DICDI
Sequence: MPLDNKVQLNENGKEVNNNNNNDEDLKIQDNHNNKEPFFNRSELVRLLIQSLNSLGYDKSAEFLEKDSGISLQSKEINQFSECVVSGDWNKVEELLPFLKLNEFDTNNVKFLVYSQKFLEYLENHKIKEALECLRLEITPYTKDTSRLQVLTSLIMTSNSSETKKQIKQRSSRVNLLDDIRKYVNPNIMLPENRLEQLIKQSIQYQMGKCLYHNTSEQFINLFKDHTCDKSQMPLDVLFTLKDKHRDEIWFITFSHDGQRLASSSKDNTIIIWDMSTIYLDQPTEPKVMFILLGHTKEVSHLSWSPNDKYLLSASNDSTVKLWNTNDGTLLKTFTKHSDAVTCCGWHPDNKRFVSGGNDKNIYLWSIENLDLTNSNNNNNNHNNNNSNINGNSINGSNNNGNNNNNISPIKSWACARVNDLSIHKDGKQLIIICQEKKLRIYDLENEKTPEVVLMETDAITSMELSNDCNFALVNTSNQEIHLWDLEKQIIVQKYRGHKQGRFVIRSCFGGVDQAFVLSGSEDSTIYIWHRSSGILLETLSRHSGTVNTVCWSPCNPFIFCSASDDQTIKVWSRSNNHNSFINNLTNK
What are the official names of this protein?
WD repeat-containing protein DDB_G0349043.
Protein: RS18_NOSS1
Sequence: MSYYRRRLSPIKPGEPIDYKDVDLLRKFITERGKILPRRITGLTAKQQRELTLAIKRSRLVALLPFINAEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SYC_RICFE
Sequence: MQIQFHLYNTLSRTKEVFNPQDQTKVKMYVCGPTVYDNPHIGNSRSVVVYDLLYRIVIKIFGEQSVKYVRNITDVDDKIIDRAELLSITINELTDKVTQEFHTNMAYLGCLLPSIEPKATEHIDVMIEIIERLIAKDHAYIADNHVYFDVLSAPNYTELSNRNLEEMFEGVRIENSKTKKHPQDFVLWKPAKPNESANMNFKSPWGFGRPGWHIECSAMSYKYLGENFDIHGGGADLIFPHHTNEIAQSRCAFPDSTYAKYWVHNGFLTVNGEKMSKSLGNFITVRNLMDKEISGEVVRLFLLSSHYRRPLDYNDKAIEDAKKTLDYWYRAIENINVQKIDLPHNFMQSLLDDMNTPLAVKIINDYAKGVFISKTEEEKQLNASAIITCANFIGLMNKTPHEWFNSGVDELYINELLNKRLEAKKQKNWLLADQIRNQLLEEKIILEDKPDGTTIWRKE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURO_NATPD
Sequence: MYVGRFIVVAPDRAAYRVSSRSFPNRRIVDRDGTLTVGPTEDAPETDNPYISYNCLRTVGDDYAVVGNGTQVDPIAEKLSLGYPPRDALAESLLALDYEKDDYDTPRIAGVVGDESYIGTVRRDALIVEAVEEPTLVATYEKSEPEPTSLGADDPSELAAELYDRDLEHPVCAAGVVADGDSFEVGYYNGE
What is the function of this protein?
Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
What are the official names of this protein?
IMP cyclohydrolase, IMP synthase, Inosinicase.
What is the protein family that this protein belongs to?
Belongs to the archaeal IMP cyclohydrolase family.
Protein: FGL1_BOVIN
Sequence: MAKMFSFILVTTALVMGRGSSALENCLQEQARLRAQVYLLETRVKQQQVKISQLLHEKQVQLLDKGEENSVIDLGGKRQYADCSEIFNDGYKQSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRDWSDYENGFGNFVQKNGEYWLGNRNLHLLTTQGDYTLKIDLADFEKNSRYAQYKNFKVGDEKNSYDLHIGEYSGTAGDSLTGNFHPEVQWWASHQRMKFSTWDRDNDNYEGNCAKEDQSGWWFNRCHSANLNGFYHKGPYTAKTDNGIVWHTWHGWWYSLKSVVMKIRPNDFIPNIV
What is the function of this protein?
Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3.  Responsible for LAG3 T-cell inhibitory function.  Binds LAG3 independently from MHC class II (MHC-II).  Secreted by, and promotes growth of, hepatocytes.
What are the official names of this protein?
Fibrinogen-like protein 1.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the blood plasma.
Protein: SEC24_PICGU
Sequence: MSKRRAYPQPQYAISQDQAPATPPVGASAAYGVPQVAQQFQQMNINPQPGAQPGAAVPQGYGYNQYGQQPQPGQAYDPYQQPPQANTGFGGQQQTPSQQPYQQQGGYFGAGAGGQAAPALPLNQLYTTDLSRELPPPISDLSLPPPPLVIPSNTAIVPTSEDSNASPDYFRSTLNVIPNNGTLLKRSKLPLALVVRPYTTLRVDQENIPAASDTIISRCRRCRCYINPFVTLTEQGRRWRCNLCNLQNDIPAAFEYDETRGVPRNKFDRVELNHSVVEFVAPKEYMARAPQPIVFVFVIDVSADAVNSGLTSTVTRTILESLDRIPNQNKTARVAFLGVDSNLHYFRFDEGLEGSELLIASDLDEPFLPSPSGLLINLEENRPAIEKLLIDFPTYFENTANTQFALGPALKAGHKMIANIGGKLITFAASLPNIGEGKLSVRDEASHSGQPKESQMLLGAADKFYKSFAVECNSAQVTVDLFLTSARYQDVATLSNLPRFTAGQTHFYPAWSCVKPEDVTKLSKEISEHLSMDIALEAVLRVRSSTGMRSSAFYGNFFNRSSDLCSFPSFPRDQSYVIEMSIEETITKPVVYFQAASLHSTSYGERRIRVMNLAIPTSSKLDDIYASADQLAIANYFTHKAVEKALASSLPDARNYIVKSIVDILNVYKKELVAGNVSGSSPLQISTNLRMLPLLLFSLTKHLGLRGERVPSDHRAAALNRLSSLPIPHLIKYIYPTVYSLHNMGDECGLPEQTVTVNEETGEEETTSGGILLPEPINDTKASWENYGLYLIDNSSEVFLWVSGDVVPDLVYDLFGTDNLYSIPTGKTELPELQPDESEFNYRVRNILGKIREQKDQITWKNLYVVIGGSSNEPIEISQQRDLMALRMWALSCLVEDKTANEQGYREFLTSLKGKVAQ
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC24.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GATA_BACAN
Sequence: MSLFDHSVSELHKKLNNKEISVTDLVEESYKRIADVEDNVKAFLTLDEENARAKAKELDAKIGAEDNGLLFGMPIGVKDNIVTNGLRTTCASKILANFDPIYDATVVQKLKAADTITIGKLNMDEFAMGSSNENSGFYATKNPWNLDYVPGGSSGGSAAAVAAGEVLFSLGSDTGGSIRQPAAYCGVVGLKPTYGRVSRYGLVAFASSLDQIGPITRTVEDNAYLLQAISGLDRMDATSANVEVGNYLAGLTGDVKGLRIAVPKEYLGEGVGEEARESVLAALKVLEGMGATWEEVSLPHSKYALATYYLLSSSEASANLSRFDGVRYGVRSDNVNNLMDLYKNTRSEGFGDEVKRRIMLGTFALSSGYYDAYYKKAQQVRTLIKNDFENVFANYDVIIGPTTPTPAFKVGEKVDDPMTMYANDILTIPVNLAGVPAISVPCGFGANNMPLGLQIIGKHFDEATIYRVAHAFEQATDHHTKKASL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: IVD_PONAB
Sequence: MATATRLLGWRVASWRMRPPPAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTVAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKVPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH
What is the function of this protein?
Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway.  To a lesser extent, is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA.
What are the official names of this protein?
Isovaleryl-CoA dehydrogenase, mitochondrial, IVD, Butyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CYSO_MYCBO
Sequence: MNVTVSIPTILRPHTGGQKSVSASGDTLGAVISDLEANYSGISERLMDPSSPGKLHRFVNIYVNDEDVRFSGGLATAIADGDSVTILPAVAGG
What is the function of this protein?
In its thiocarboxylated form (CysO-COSH), is the sulfur donor in the CysM-dependent cysteine biosynthetic pathway.
What are the official names of this protein?
Sulfur carrier protein CysO, 9.5 kDa culture filtrate antigen cfp10A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein CysO family.
Protein: YOY6_CAEEL
Sequence: MVTPLTGTHEGVSCDGCAFTAFAGNRYKCLRCSDYDLCFSCFTTKNYGDQQTIADIPIHDESHPMQLILSSVDFDLVYQGDPTRHYDERKIVSFTCPYCNITGLTERQFGTHVLSQHPEAPGYSVICPLCIGNTEMEHIQSKETENLSVHWTEIHLHTMENLFRSTEPITTRPVQRRPMLARRGNRAGVSRTAAQGRPLQDEIGAEMAALLRNMGPDSVEDIRRFTEMMTVPLLPGIRSSQRLMTSTGDRPTVVVESAVTHQDPNVQQVIRPLATIPIYPPTSDESGDETPQPAADSADESEDDNDIQELDDMQPIVEDEALKKDEFWKTLKTRISEEDVDLILETMKSTAKVKEDIDDKMPVWTQRPLKRLANAAQVTTTSDSEGDPGWLPLSFETTPIRSTGCGGYWSDKRFLRPRKMQREQSVASSNAEIMEKAEIALALIRASCLHEPVFTDPTKPDIALKEALQHLRLGEKPAKMMEYQAAEELVNMPERDPITTGEMEVEIPDFTARGYGQIVDGNIPLGVVPEADEAITNSEDEEIVGGETSGDDEDEQEDDENDSQDSSVPEEINID
What are the official names of this protein?
Uncharacterized protein ZK652.6.
What are the subcellular locations of this protein?
Nucleus.