PharMolix/UniProtQA huggingface dataset:
Protein: SYP_LAWIP
Sequence: MRWSQCYIPTLKEAPGDAELLSHKLLIRAGMIRKLTSGIYTWLPLGLKTLNKAISIIRSEMNRIGAEEILMPMVQPADLWKESGRWDQYGKELLRIKDRHDREYCLGPTHEEVVTHLLRGEVRSYRQLPINVYQIQTKFRDEIRPRFGLMRAREFLMKDAYSFDQDNEGADISYHTMFDAYKAIFTCMALDFRAVEADSGSIGGNFSHEFMVIADSGEDTIAFCRKCDWAANIEHAATLPPQTKALTLEKSMEEVVTPGQHTIKAVSTFLTIPEQQIIKTILYTIDNKPVAVLVRGDREVNEVKVKNMLDATVITMATPEQVHQWTGAPVGFAGPVGFTAGPIIADHELMVYNDWVVGANKPDKHILHVDLARDVQNITFADIRLITDADGCPSCGREIALTKGIEVGHVFKLGTKYSKSMNAFFLDENGEEQLMVMGCYGIGVSRVIAACIEQNNDKYGIIFPPPLAPFEIMLINLDPRDESVVMKASEIYQFFLSEGIEVFLDDREERPGIKFNDADLLGFPIQVIIGAKSLANGIIEVKNRKTGEKSSFSLERFFTDFYSWRDTVYVTWGLS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_SALEP
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTGMVGKLFAPIMLTWFLILAVLGLRSIIANPEVLHALNPVWAVRFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPDWALIPLLILAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWLLYFAVVVVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARKNWHWNKYFVALILIAFLCVDIPLFSANLDKLLSGGWLPLSLGLIMFTIMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRALSVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLIVGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEF23_ARATH
Sequence: MTTTMKIMSFAMLLVLLFSIDVVEGSGSSLCCNTHAKFGACNTYQDRKRCNKWCLDGCDNKKGGFCKRFAGGAKKCHCYC
What are the official names of this protein?
Putative defensin-like protein 23.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PI4KA_BOVIN
Sequence: MAAAAARGGGGGGGGGSFGSGAGGGASRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDSVVPYLLRLLKGLPKVYWVEESTARKGRGTLPVAESFSFCLVTLLSDVAYRDPSLRGEILEALLQVLHVLLGMCQALEIQEKEYLCKHAVPCLLGIVRAFGRHSSSEDSILSRLFPRAPAHSPRVPEELEGVRRRSFNDFRSILPSSLLTVCQEGSLKRKASSASSVAQVSPERGAPPPSPPGGSAFHCLEASYSPNGSTSESDYYFSAVSSSFSVSPLFNGVTYKEFSIPLEMLRELLNLVKKIVEEPVLKSLDAVVTGVIEASPSADLCYGAFSDPLYVAVLRMLRDTLYYMRDLPTSFVKEVHDFVLEQFNSSQGELQKILHDADRAHSELSPLKLRCQASAACVDLMVWAVKDEQGAENLCVKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVVPSPVLVKLYKCHSQYHTVAGNDIKISVTNEHAESTLNVASGKKSQPSMYEQLRDIAIDNVCRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEPKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRSVLQYNSAMKNDTVTPAELSELRSTIVNLLDPAPEVSALIGKLDFAMSTYLLSVYRLEYMRVLRSSDPARFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTKENEEELERHAQFLLVSFNHVHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDVPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLSKHQNWVSGLSQHTGLAMATESVLHYAGYNKQSTSLGATQLTERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFSDATGHTSDLNKMMVQELKAALGAGDAQQYTQAMFKLTAMLISSRDCDPQLLHHLCWGPLQMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWQMTVEQKFGLFSAEMKEADPLAASEASQPKPCAPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFCSLLQRSLSLSIGGTAGSMNRHVAAIGPRFKLLTLGLSLLHADVLPNATIRNVLREKIYSTAFDYFSCPPRFPTQGEKRLREDISVMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLDIAVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGESSVANWRSKYISLSEKQWKDNVNLAWSISPHLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPADPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASQSQLLAHQFIWNMKTNIYVDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDPEEEGSMQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHLIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFILKVIQNCFLSNRSRTYDMIQYYQNDIPY
What is the function of this protein?
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate.
What are the official names of this protein?
Phosphatidylinositol 4-kinase alpha, PI4-kinase alpha, PI4K-alpha, PtdIns-4-kinase alpha.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Localization to the plasma membrane is mediated by the PI4K complex and association with EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and FAM126 (FAM126A or FAM126B). Localization to the plasma membrane is regulated by TMEM150A.
Protein: GLGA_CLONN
Sequence: MNILFATSEAFPFIKTGGLGDVSYALPKALKRKGTDIRVILPKYSSIPQEYADNMRKVAEFTVGVGWRSQYCGLLELEKDGVKFYFIDNEYYFKRNSAYAQMDDGERFSFFSRAILESINHISDFTPDVLHCNDWHTAMTIPMLRDQYFNNPKLNNIKTVYTIHNLKYQGRFGKEILWELLGFGDEYFSEDKFKYYDSISFMKAGIVYADAITTVSPTYAEEIKTEYYGEGLNGLLQSRSKDLYGILNGIDTDVNNPSTDMFLFDKYDVNNLEAKARNKEKLQEMLHLPKNRDIPMIGIVARLEEQKGFELIKEVIEELLQENIQLVVLGTGDQRYEDMFKFFAWKYPDKLSANIYFDGGLAQKIYAASDMFLMPSRFEPCGIGQLIALRYGSVPIVRETGGLNDTVFSYNEFTGEGNGFSFTSFNARDMLYTIKRAIGFYYDKDVWSKLVQRGMNGDYSWEKAAEKYMRVYSNILHKW
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: SYI_STAAT
Sequence: MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRFL_HORSE
Sequence: LGLCLAAPRKSVRWCTISPAEAAKCAKFQRNMKKVRGPSVSCIRKTSSFECIQAIAANKADAVTLDGGLVYEAGLHPYKLRPVAAEVYQTRGKPQTRYYAVAVVKKGSGFQLNQLQGVKSCHTGLGRSAGWNIPIGTLRPYLNWTGPPEPLQKAVANFFSASCVPCADGKQYPNLCRLCAGTEADKCACSSQEPYFGYSGAFKCLENGAGDVAFVKDSTVFENLPDEADRDKYELLCPDNTRKPVDAFKECHLARVPSHAVVARSVDGREDLIWRLLHRAQEEFGRNKSSAFQLFKSTPENKDLLFKDSALGFVRIPSQIDSGLYLGANYLTATQNLRETAAEVAARRERVVWCAVGPEEERKCKQWSDVSNRKVACASASTTEECIALVLKGEADALNLDGGFIYVAGKCGLVPVLAENQKSQNSNAPDCVHRPPEGYLAVAVVRKSDADLTWNSLSGKKSCHTGVGRTAAWNIPMGLLFNQTGSCKFDKFFSQSCAPGADPQSSLCALCVGNNENENKCMPNSEERYYGYTGAFRCLAEKAGDVAFVKDVTVLQNTDGKNSEPWAKDLKQEDFELLCLDGTRKPVAEAESCHLARAPNHAVVSQSDRAQHLKKVLFLQQDQFGGNGPDCPGKFCLFKSETKNLLFNDNTECLAELQGKTTYEQYLGSEYVTSITNLRRCSSSPLLEACAFLRA
What is the function of this protein?
The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions.  This function contributes to the antimicrobial activity.  Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites.
What are the official names of this protein?
Lactotransferrin, Lactoferrin.
What is the protein family that this protein belongs to?
Belongs to the transferrin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Secreted into most exocrine fluids by various endothelial cells. Stored in the secondary granules of neutrophils (By similarity).
Protein: CNGB1_HUMAN
Sequence: MLGWVQRVLPQPPGTPRKTKMQEEEEVEPEPEMEAEVEPEPNPEEAETESESMPPEESFKEEEVAVADPSPQETKEAALTSTISLRAQGAEISEMNSPSRRVLTWLMKGVEKVIPQPVHSITEDPAQILGHGSTGDTGCTDEPNEALEAQDTRPGLRLLLWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPGICDVQTISILPGGQVEPDLVLEEVEPPWEDAHQDVSTSPQGTEVVPAYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQSEEDGTRPQSTSDQKLWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQVEDTDADSCPLMAEENPPSTVLPPPSPAKSDTLIVPSSASGTHRKKLPSEDDEAEELKALSPAESPVVAWSDPTTPKDTDGQDRAASTASTNSAIINDRLQELVKLFKERTEKVKEKLIDPDVTSDEESPKPSPAKKAPEPAPDTKPAEAEPVEEEHYCDMLCCKFKHRPWKKYQFPQSIDPLTNLMYVLWLFFVVMAWNWNCWLIPVRWAFPYQTPDNIHHWLLMDYLCDLIYFLDITVFQTRLQFVRGGDIITDKKDMRNNYLKSRRFKMDLLSLLPLDFLYLKVGVNPLLRLPRCLKYMAFFEFNSRLESILSKAYVYRVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGNSYIRCYYFAVKTLITIGGLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKKARRMLRSNNKPKEEKSVLILPPRAGTPKLFNAALAMTGKMGGKGAKGGKLAHLRARLKELAALEAAAKQQELVEQAKSSQDVKGEEGSAAPDQHTHPKEAATDPPAPRTPPEPPGSPPSSPPPASLGRPEGEEEGPAEPEEHSVRICMSPGPEPGEQILSVKMPEEREEKAE
What is the function of this protein?
Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties: it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit.
What are the official names of this protein?
Cyclic nucleotide-gated cation channel beta-1, Cyclic nucleotide-gated cation channel 4, CNG channel 4, CNG-4, CNG4, Cyclic nucleotide-gated cation channel gamma, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-1, CNG channel beta-1, Glutamic acid-rich protein, GARP.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGB1 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENT_ENTCO
Sequence: TQRDTLTKGMTQGQIVAGPDDTKIDQSIMDQGVCATIALPFDIHVAQSVKNVMFMFAWTQKHGLAVNNLVILGVPGYLNMWKRFGESTDEPSESSKRCCYEKPTDPVSGEIVTPAFDPADEISEITHQEESADIKPVRLLDARLLGYTWVTQNHSWIVAYSDEPIKDGNEVVTLRNIGNNNFCDALRKCTDKSACIHQYLQFAWNSFGDPTVRTRQVVFEVVGWADSDTTNNNSDTLFYRTTQADNWQVLTESKTNTIGLAEVDWFNFKYETKQEVSIEIARQTWTSTLNAGVSTVSRVPKVPIKVKINVDTFLKVLFAVYKADLYDIFLQFASVFKKGGNRQYWLNYTQEPNTKSNYNHKIYNDKIRYLQEDVQVHPNETQSKWWWWSFKKVALTTMTVVALTRFKASGINGQYISARQFSGGETVSPYRLAAPFDSCLWRRSPNPLGTDGLKVALAHHPLAGASNRNKLRVSIPAQCICSITA
What is the function of this protein?
Cytolytic protein with insecticidal activity.  Acts as a pro-inflammatory agent.
What are the official names of this protein?
Cytolytic protein enterolobin.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: ESXC_MYCPA
Sequence: MSDPITYNPGAVADFATDVASRAGQLQSIFDDTSNRTHALQEFFAGHGASGFFEAQAQMLSGLQGLIDTIRQHGQTTSHVLDSAISTDQHIAGLF
What are the official names of this protein?
ESAT-6-like protein EsxC, ORF3890c.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-2 / type VII secretion system (T7SS).
Protein: RL11_SULIY
Sequence: MPTKSIKIMVEGGNVKPGPPLAPTLSQLGLNVGEVVKKLNEATSSFKGMSVPVTIEVDSNTKKYEIKVGIPTTTALLLKEAGASEPSGDPAHKKIGNLSLEQVIKIAIMKKPGLTTKSLKAAVKSMLGTAKSIGVTVENKDPKELVKEVEEGKYDDLLAKYENEWNEVKE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SED1_ARTOC
Sequence: MSTMIFMYFIYIVLYASGIAANLSYHVHEKRSIPVWWQRVSRIDPHAFLPLTIALAQQNLEHAEDYLLSVSDPSSPQYAQYWTAEAVAAKFAPSEPTARKVMSWLNQSGIAPAGVRRSKSGGELYMNITAQEAEKLLHTTFYIYKHQLTNKTLAICEKYSVATFVEKYVDFITTTEQFHHGLRRRSFQDPEPRMPSGKSPGHYVELADDSFPFPYLSFGSSVGLLKNKILSDSLPSNCDKLITPDCLRALYHIPVRNTSHPDNSLGIIEFTWVGYLESDLDKFFNIFQPSMVGNRPKFESIDGGFIQTLVPSFAFNGEADLDIEYAMALTHPLNITNYQVGDIWSLGNMNNFLASLDSTYCSAVDPVYDPIYPDPTPANPPLPSGYNSSDCGTHKPTKVISISYAYEEGEFSPAYERRQCLEYLKLGLQGVTVVFASGDHGTATRDGMCGNTVIDSNQISDHEPSYVPTFPSTCPYVTSVGGTQVPANGSVLDAEVAFDTIITSSDGNVSSRLTSAGGFSNVFAVPGYQATATRDYLQRLQNKYTLPVNLNVTGFGSGRGFPDVAANAAAYATAVNGKLVKVYGTSASAPVFASVIAWINDARLNMGKQPVGFVNPVLYANPQVLNDVAKGSNYDCANLPAYHASSGWDPVTGLGTPNFDRMLDLFLQLS
What is the function of this protein?
Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.
What are the official names of this protein?
Tripeptidyl-peptidase SED1, Sedolisin-A.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RECU_BACC1
Sequence: MTIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIIAFWNRQNTGGRKSITKEEIVEHGSLLSCGYHPRIDYIRVLDTVYFS
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAR1_YEAST
Sequence: MDTQIAITGVAVGKEINNDNSKTDQKVSLPKADVPCIDKATQTIIEGCSKDDPRLSYPTKLETTEKGKTKRNSFACVCCHSLKQKCEPSDVNDIYRKPCRRCLKHKKLCKFDLSKRTRKRKPRSRSPTPFESPMVNVSTKSKGPTDSEESSLKDGTSYLASFPSDPNAKQFPNSRTVLPGLQQSLSDLWSTLSQPPSYGAREAETTSTGEITTNNHTKSNGSVPTNPAVLASNDEHTNISDAPVIYSTYNSPVPISSAPTSINSEALFKHRPKIVGDEETQNVKVKRQKKSYSRHMTRSFRKQLQSLIISQKGKIRDISMKLDTWSKQWNDLVEKSMFLPTIADPVSVGIISHEEATLRLHLYKTEISYLSKLPFIKVEENVSVDELRKKKPILFSVIMSCVSIVLTPKQTTRGTIMKLDSFVLNLITNQIFKANNKSIEIIESLSTLCLWYNFFEWSSKTRYHIFNYICCCLTRDLGPTYVNRSFGMFSDEDPKRFKSPLELYSNGASLTLLVYISALNISIFLRQSIQARWSHVTEKACEDLVKETKKSRHYDNDKLLLDSADDPILVQFAKMNHVLENIHTHLHERDLNDDEFDDPIFTKKYLNKLMEKYHKQLQEIFTKLDRNRPRVIAFYYSVEAYLYQYKLAVFIGEMSHTINEKVELPREIMDDFVKCYHCCKSALEEFSKLEPILITSLPLFHTSRIIYTVGMLLLKLRYSVVAIPSFHDLMPLTDDAIALVIGVNNLLEKTSELYPFNNSLYKFRYVIALFCQTYANKVIDVADRYNAEREKLKEKQVIDEVSNGHDGTKPINAYVTESQKMPTEEDPIIDNNTNQNITAVPDEMLPVYSRVRDDTAAMNLNINSTSYMNESPHEHRESMTGTTLLPPPFISNDVTNSADSTNIKPSPSSSVDNLNDYLTDINSLAWGVNSLNDEFWTDLFMNDI
What is the function of this protein?
transcription factor which binds to a weak acid response element (WARE) to mediate stress induction of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively.
What are the official names of this protein?
Weak acid resistance protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAA1_TREDE
Sequence: MVPVLIFFGATASGKTSLASEIFSYKHSKDFSKEGGISALSACAEIISADSVQVYKHMHIGSASPSKEELEDLPHHLIAIKEPSEEFSAADFVKEADKLCPEIYRRGKLPVLMGGTAFFLKNFLYGLPVTPTADPKIREHFQKRAKEEGAGILLEELKKIDPETAERLHVHDEYRIIRAHEVFAASGKPLSSFALPENPREKYEFFILSIERTRSLLYERIEKRVDAMFAEGLYDEVKKLYEMGYTSESPGLKAIGYREFFDENKRLKPESDLEEVSALIKRNTKHYAKRQETFFKTIPDVHRYFIEDKAEISRLYKDICGFYKKLLK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: DIOX4_RUTGR
Sequence: MAPTKDSVIHMGAESWDEISEFVTKKGHGVKGLSELGIKTLPKQFHQPLEERFSEKKILERASIPLIDMSKWDSPEVVKSICDAAEHWGFFQIVNHGVPLETLQRVKEATHRFFALPAEEKNKYSKENSPINNVRFGSSFVPHVEKALEWKDFLSMFYVSEEETNTYWPPICRDEMLEYMRSSEVLIKRLMEVLVVKGLKVKQIDEIREPMLVGSRRINLNYYPKCPNPELTLGVGRHSDISTFTILLQDEIGGLHVRKLDDTGNTWVHVTPISGSLIINIGDALQIMSNGRYKSIEHMVVANGTQDRISVPLFVNPKPQAILCPFPEVLANGEKPVYKPVLCSDYSRHFYTKPHDGKKTVDFALMN
What is the function of this protein?
2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD) involved in scopoletin and umbelliferone biosynthesis (PubMed:22168819).  Converts feruloyl CoA into 6'-hydroxyferuloyl CoA, and p-coumaroyl CoA into 2,4-dihydroxycinnamoyl-CoA (PubMed:22168819).  Has no activity with cinnamic acid, caffeic acid, p-coumaric acid, ferulic acid, cinnamoyl-CoA and caffeoyl-CoA (PubMed:22168819).
What are the official names of this protein?
Bi-functional coumaroyl CoA and feruloyl CoA ortho-hydroxylase Diox4, 2-oxoglutarate-dependent dioxygenase 4, 2OGD Diox4.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: LARP1_CAEEL
Sequence: MAEKQPMLSFAKVVSGQAEDASSPSQQVQHTQDSSHSSTQNENSQPEKQAHPPHNRREKENVGGRSERPRGEGKGKRRNNRKGDRKPRGETKTEKPAEKVATEEVKPVEIPVVLEPAPLPAINAWFKNKEEAEAAAAAAQKEQKSETAADQFIITATPVVQKSSAPIPEKKRAVEPTPKQAAPIKEKSKSRESKKEPWKTSTAPAATAPVTETVTVAATQDWPTLAKAELNGHVSPSNSDDNNESSSNSQHKTGGKMTKNSWKKVDISVDYGSKGKGAPRGNGGEKGTRRSANDEAVRRRSGEEDSASGDEQQYWSRSKDNKSPINEMSSDRVVDSGSNGIYYQQGGTHGWKKKVNNKAGSDMPTPPNSTSPHQSESNSPEHLPKDKAPIMNGNAKNAPAANRNGNNTSTAKTGDYWHKNGGERKEDKSQPKAYYQRNDRFQARANPHAPPKLTAAQRKERGPLPRWEDIEAGDDNFDYMTLMEAQYSQYYGAPQQFEHQLDPHQASILIQQAQQHMASFAPFRPPMPMLSPHLMSPPLDRDGGVTSPVSNGEPINTAIPFAPIYNPPTAPRPVTDDTLKEYVRKQIEYYFSEENLQKDFFLRRKMGPEGYLPVALIASFPRVRSLTEDYSLILEALKDSTKVDMSPDGLQIRAPVNPTIWPLMPTVSGADSLPGPSSQAPQQFRQNGPAATAAPVESQPQASSSKPQQPEEWEEVKTRKGKGKGRLTSGSQSTNDNKRQPQQQQKSLQQSGSDQPDLDFQFDNEISGGGGSAQTPKRPEKSKKAFLSAIDSEEIGDDVISKLIIMTPSRRTLDRTGDFSTRSQNQGEFNEEVEIGLRRYEEELWTVPQEKDIPTSKVSTISAEQFNEMRGNEDAKKTSDEPPEIPLPSGTQPTPDSVWTKKAKERAAASVTVPKSPMQRRESEEQKMNRFYPISKPTAPLDAKSPRKKKTRHSEKPPVEMPVAWVLGREDALPAAPIGIAASSSQVPANHPSISLLQEDRFVQNVYSTWRQACLKQRKSLGYDCAEMNTLYRFWSFFLRDNFNRNMYEEFRKLALEDAEIGSRYGIEALFRFYSYGLEKKFRPEIYKNFMKDVTTDVQKGELYGLEKLFAFLQRSKIAKQLVVDDYLTKELNKYKSTDDFRNLPQSTKK
What is the function of this protein?
RNA-binding protein that promotes oogenesis by repressing fem-3 expression during germline development (PubMed:18515547, PubMed:20663921).  Binds poly-U and poly-G stretches of RNA in vitro (PubMed:18515547).  Regulates target RNAs expression either by regulating their stability or translation (PubMed:20663921).
What are the official names of this protein?
La-related protein 1, La ribonucleoprotein domain family member 1.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: Y1460_YERPS
Sequence: MKLGLVAGMLAVCFSFSSVAMTLKLTPEIDLLVVDGKNMSGSLLKGADSLELNSGMHQILFKVIKPLPTDPLVLYSSPPLIVVFNAHNTRSVAIKLPVINTLRDGHQFSKNPLYQLIGDNGHPLSVRHDVLRQDHLNNSTTLETVMAAYNVGKYNASVPAFAAIPPSPVSAVPGTTIPVAGVNTPHKTASLQGENVTEQMLQYWFLQANPETQKRFLIWAKKQPIH
What are the official names of this protein?
UPF0319 protein YPTB1460.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: YDJK_ECOLI
Sequence: MEQITKPHCGARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGLILAQLKALGWTDNSTTATFSAITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDFLIACRFVMGVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSYPLCSLIAMGLTPLISAEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEAEKVMRSIEEGVIRQTGKPLPPVVIADDGKAPQAVPYSALLTGVLLKRVILGSCVLIAMNVVQYTLINWLPTIFMTQGINLKDSIVLNTMSMFGAPFGIFIAMLVMDKIPRKTMGVGLLILIAVLGYIYSLQTSMLLITLIGFFLITFVYMYVCYASAVYVPEIWPTEAKLRGSGLANAVGRISGIAAPYAVAVLLSSYGVTGVFILLGAVSIIVAIAIATIGIETKGVSVESLSIDAVANK
What are the official names of this protein?
Putative metabolite transport protein YdjK.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOC_METRJ
Sequence: MNQEVMNLFNQQAQPVSFDQIKISISSPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGVICEKCGVEVTLARVRRDRMGHIELAAPVAHIWFLKSLPSRIGLLLDMALKDLERILYFESYCVIEPGLTPLKERQLLSEEEYLRAQEEYGEDSFTAMIGAEAIRRILQELDLDKIANDLREEIAVTTSELKPKKLLKRLKIIEAFQMSGNKPEWMILTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYARLDAKGFSATVKQAKKLVEKEKPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIVAEGAPGEYKPDNAKNPMQGVYGDMGELEHALAAKAVSLHSKIKWRWTGIGPDGEPLTKTYETTPGRVILSGALPKHAKVPFDVVNKLMTKKEISAMIDTVYRHCGQKESVIFCDRIMALGFNHAFKAGISFGKDDMVVPENKWSIVDTTRALVKDYEQQYNDGLITQGEKYNKVVDAWAKCSDKLAAEMMGRISSVQKDEKGADKQVNSIYMMSHSGARGSPAQMKQLAAMRGLMAKPSGEIIETPIISNFKEGLDVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDAVIREVDCGTTSGIKMRAIVDAGQVVATLATRILGRATAEDLVAADGTVIVKTGETIEERHLPAINAAGIQEVKIRSVLVCATKSGVCATCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQIADSSFIESSFEGTIKIRNRAVAKNTDGDLIATGRNVAVVIVGSDGVERAVHRLQYGAKLRVDEGDKIKRGQRIAEWDPYTRPILTEVDGIVAYEDLVDGQSMTETTDESTGIAKRVVVDWRGSARTSDLKPAMVVVDRDGKALKLPRGSDARYFLPVDAIIGFDPGATVKAGDILARVSTDSAKTRDITGGLPRVAELFEARRPKDAAIIAEKSGTIAFGRDYKNKRRLTLTPHDGSEAVEYLIPKGKHIHLQDGDVVELGDYIVDGNPAPHDILAIKGVEELAAYLVNEIQEVYRLQGVSINDKHIEVIVRQMLQKVEVTDGGDSDILSGDQIDRTELTDYNEKLLAEGKKPIQGVPVLLGITKASLQTKSFISAASFQETTRVLTEAAVNGKVDTLEGLKENVIVGSLIPAGTGSMVADIRSIARRRDAMILQQKQAESGAMPVEELPPAAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.