PharMolix/UniProtQA huggingface dataset:
Protein: MAN2_SPOFR
Sequence: MRTRVLRCRPFSTRILLLLLFVLAFGVYCYFYNASPQNYNKPRISYPASMEHFKSSLTHTVKSRDEPTPDQCPALKESEADIDTVAIYPTFDFQPSWLRTKEFWDKSFEDRYERIHNDTTRPRLKVIVVPHSHNDPGWLKTFEQYFEWKTKNIINNIVNKLHQYPNMTFIWTEISFLNAWWERSHPVKQKALKKLIKEGRLEITTGGWVMPDEACTHIYALIDQFIEGHHWVKTNLGVIPKTGWSIDPFGHGATVPYLLDQSGLEGTIIQRIHYAWKQWLAERQIEEFYWLASWATTKPSMIVHNQPFDIYSIKSTCGPHPSICLSFDFRKIPGEYSEYTAKHEDITEHNLHSKAKTLIEEYDRIGSLTPHNVVLVPLGDDFRYEYSVEFDAQYVNYMKMFNYINAHKEIFNADVQFGTPLDYFNAMKERHQNIPSLKGDFFVYSDIFSEGKPAYWSGYYTTRPYQKILARQFEHQLRSAEILFTLVSNYIRQMGRQGEFGASEKKLEKSYEQLIYARRNLGLFQHHDAITGTSKSSVMQDYGTKLFTSLYHCIRLQEAALTTIMLPDQSLHSQSIIQSEVEWETYGKPPKKLQVSFIDKKKVILFNPLAETRTEVVTVRSNTSNIRVYDTHKRKHVLYQIMPSITIQDNGKSIVSDTTFDIMFVATIPPLTSISYKLQEHTNTSHHCVIFCNNCEQYQKSNVFQIKKMMPGDIQLENAVLKLLVNRNTGFLRQVYRKDIRKRTVVDVQFGAYQSAQRHSGAYLFMPHYDSPEKNVLHPYTNQNNMQDDNIIIVSGPISTEITTMYLPFLVHTIRIYNVPDPVLSRAILLETDVDFEAPPKNRETELFMRLQTDIQNGDIPEFYTDQNGFQYQKRVKVNKLGIEANYYPITTMACLQDEETRLTLLTNHAQGAAAYEPGRLEVMLDRRTLYDDFRGIGEGVVDNKPTTFQNWILIESMPGVTRAKRDTSEPGFKFVNERRFGPGQKESPYQVPSQTADYLSRMFNYPVNVYLVDTSEVGEIEVKPYQSFLQSFPPGIHLVTLRTITDDVLELFPSNESYMVLHRPGYSCAVGEKPVAKSPKFSSKTRFNGLNIQNITAVSLTGLKSLRPLTGLSDIHLNAMEVKTYKIRF
What is the function of this protein?
Catalyzes the first committed step in the biosynthesis of complex N-glycans.  It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
What are the official names of this protein?
Alpha-mannosidase 2, Alpha-mannosidase II, Class II alpha-mannosidase, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 38 family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: HLDE_SHEHH
Sequence: MKISLPAFEKAKVLVVGDVMLDRYWAGPTARISPEAPVPVVKVEQLEDRPGGAANVAINIATLGGSASLAGIVGEDETADALTLGIQTLGVEPNWHKVAGKPTITKLRVMSRNQQLLRLDFEESYTQAESEALLAKTLPELDKVDVAVLSDYAKGAIISPQSFIQAANAKGVKVLVDPKGSDFSKYRGAYLLTPNMSEFEVVVGKVESEADLVAKAQGLLEAYDFTAMLVTRSEKGMTLITRDQPELHIPTVAREVFDVTGAGDTVISALATAIAAGSDLPQACAIANTAAGIVVAKLGTSTVTRLELIEALSLSHGETGFGAVSEDQLAYALEQAKLRGERVVMTNGCFDILHAGHVSYLQQARALGDRLIVAVNTDASVKRLKGEGRPVNTEDRRMTVLAALASVDWVVPFTEDTPQRIISRLLPDLLVKGGDYKVEDIAGGAEVMAAGGQVKVLGFEDGISTTAIIQNIMANQ
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: AGD7_ARATH
Sequence: MAAARRLRTLQSQPENKVCVDCSQKNPQWASISYGIFMCLECSGKHRGLGVHISFVRSVTMDSWSEIQIKKMDAGGNERLNNFLAQYGISKETDIISKYNSNAASVYRDRIQALAEGRQWRDPPIVKESVGGGLMNKKPPLSQGGGRDSGNGGWDNWDNDDSFRSTDMRRNQSAGDFRSSGGRGAPAKSKSSEDIYSRSQLEASAANKESFFAKRMAENESKPEGLPPSQGGKYVGFGSSPGPAPRSNQQSGGGDVFSVMSEGFGRLSLVAASAANVVQTGTMEFTSKVKEGGLDQTVSETVNVVASKTTEIGQRTWGIMKGVMAIASQKVEEFTKEEASTWNQQNKTEGNGYYQNSGIGNKTANSSFGGSQSSSSGHNNSYRNSNSWDDWGEENNSKKEAAPKVSTSNDDDDGGWAGWDDNDAKDDDFYYQPASDKKSVGHNGKSDTAWTGGGFL
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor (ARF).  Involved in protein trafficking by controlling ARF1 activity; may participate in COPI vesicle formation at the Golgi complex.
What are the official names of this protein?
ADP-ribosylation factor GTPase-activating protein AGD7, ARF GAP AGD7, Protein ARF-GAP DOMAIN 7, AtAGD7, Protein PDE1 SUPPRESSOR 1.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: RL5_METVS
Sequence: MSFQEVWEKEPMKKPRIQKVTVNFGVGEAGDRLTIGAKVIETLTGQAPVRTLAKQTNPAFGIRKKLPIGLKVTLRGKNAEEFLENAFVAFKVSGKVLYASSFDKVGNFSFGVPEHIDFPGQKYDPTVGIYGMDICVTFEKPGYRVKSRKLKRSHIPAKHLVKKEEAIEYIEKKFGAEVVME
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RPOB_AZOC5
Sequence: MAQTFTGRKRIRKFFGKIKEVAEMPNLIEVQKASYDQFLQIEEPKGGRADDGLQAVFKSVFPISDFSGAAMLEFVRYEFEPPKYDVDECRQRGMTFAAPLKVTLRLIVFDVDPDTGAKSVKDIKEQDVYTGDIPLMTMNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAARIIPYRGSWLDIEFDAKDIVYARIDRRRKIPVTSLLFALGLDSEEILNTFYEKILYTRAKDGWRMPFDPKRMKGYKAVADLIDADTGEVVVEAGKKLTVRAARQLVEKGLKALKISDDEMVGQYIGEDIVNVHTGEIYAEAGEEITEKVLKTLGDAGFDEIPVLDIDHINTGAYIRNTLSADKNSSREEALFDIYRVMRPGEPPTLDSAQAMFHSLFFDAERYDLSAVGRVKMNMRLDLDAEDTVRILRREDILAVIKTLVELRDGKGEIDDIDHLGNRRVRSVGELMENQYRVGLLRMERAIKERMSSVDIDTVMPQDLINAKPVAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIEAPYRRVVDGRVTDEVVYLSAMEEGKYYVAQANVPLDTDGRFQEDLVICRHAGDVLVVSPDRVDFMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRSQAPLVGTGMEAVVARDSGAAIAARRAGVIDQVDATRIVIRATGETDPSKSGVDIYRLMKFQRSNQSTCINQRPLVRVGDVVKKGDIIADGPSTELGELALGRNVLVAFMPWNGYNYEDSILLSENIVKEDVFTSIHIEEFEAMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVRAGDILVGKITPKGESPMTPEEKLLRAIFGEKAADVRDTSLRLPPGTTGTIVEVRVFNRHGVDKDERALAIEREEIERLAKDRDDEQAILDRNVYGRLSEMLVGKVAIAGPKAFKKDTEITKDALGEYPRSQWWLFAVADDALMSELEAIRAQYDESKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTNVDIVLNPLGVPSRMNVGQILETHLGWACAGLGRQVAAAVDAYYGSKDQQVLRNALVKVYGPDDIEVLDEKQITELGENLRKGVPMATPVFDGAHEADIEEHLEKAGLNPSGQSTLFDGRTGEPFDRKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGEDTFESGIPESFNVLVKEMRSLGLNVELLNSKTGRQTNPGTRENLPAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TSP_BPPCD
Sequence: MAGLVNINIEFKELATSFIQRSKAGIVAIILKDTTKMYKELTSEDDIPISLSADNKKYIKYGFVGATDNEKVLRPSKVIISTFTEDGKVEDILEELESVEFNYLCMPEAIEAEKTKIVTWIKKIREEESTEAKAVLANIKADNEAIINFTENVVVDGEEITAEKYTTRVASLIASTPNTQSITYAPLDEVESIVKIDKASADAKVQAGELILRRLSGKIRIARGINSLTTLTAEKGEIFQKIKLVDTKDLISKDIKNIYVEKYLRKCPNTYDNKCLFIVAVQSYLTELAKQELIDSNFTVEIDLEKQKEYLEGKKIAVSKMKENEIKEANTGSNGFYLINLKLVDAMEDINIRVQM
What is the function of this protein?
Polymerizes as an extended structure around the baseplate-tail tube complex.  During ejection, the sheath shifts to a contracted form, thereby making the inner tail tube protrude through the host cell envelope.
What are the official names of this protein?
Tail sheath protein, TSP.
What is the protein family that this protein belongs to?
Belongs to the myoviridae tail sheath protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Tail.
Protein: MARK3_RAT
Sequence: MSTRTPLPTVNERDTENHISHGDGRQEVTSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKITDFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWINAGHEEEELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSAELDASDSSSSSNLSLAKVRPSSDLSNSTGQSPHHKGQRSVSSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGVPSRKSGSSAVGGKGIAPASPMLGNASNPNKADIPERKKSPAVPSSNAASGGMTRRNTYVCSERCAADRHSVIQNGKESSLTEVFAYAASPASLCATSTCRLRHQRSMSVSASGHPKMVLPPIDSEGDTFKAITTPDQRTPVASTHSISSATTPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRRLPTEYERNGRYEGSSRNVSSEQKDENREAKPRSLRFTWSMKTTSSMDPSDMMREIRKVLDANTCDYEQRERFLLFCVHGDGHAESLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
What is the function of this protein?
Serine/threonine-protein kinase.  Involved in the specific phosphorylation of microtubule-associated proteins for MAPT/TAU, MAP2 and MAP4.  Phosphorylates CDC25C.  Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.  Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1.  Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.  Phosphorylates PKP2 and KSR1 (By similarity).
What are the official names of this protein?
MAP/microtubule affinity-regulating kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell projection, dendrite. Cytoplasm.
Protein: COAD_FLAPJ
Sequence: MRKAIFPGSFDPLTLGHSDIIKRSIPLFDEIIIAIGVNAEKKYMFSLEDRKRFIKETFKDEPSVSVISYEGLTIDLCKKLGADFILRGLRNPADFEFEKAIAHTNRRLSKIETIFLLTAASTSFISSSIVRDVIRNGGDYSVLVPEAVRVK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_PSEF5
Sequence: MALRLILGFDYGTKQIGVAVGQAITGQARELCTLKAQNGVPDWNQVEALIKEWKPDAVVVGLPLNMDGSPSDMCVRAEKFARRLNGRFNVPFYTHDERLTTFEAKGERLARGGQKGSYRDNPVDAIAAALLLQGWLDENAGLLNT
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_THEAC
Sequence: MPDSIVHVKKGQRFLDVIKDKNVVAVKIDSVLHDLRDVAERDVDAIPVSVYSDDGLYILRHSAAHLLANAVTNLYPDALPNTGPVVENGFYYDFDMKPIGEEDLAKIEDEMRRIQKENVPIERIVYQKADLLRIFAKNPYKIRIIEDNVSDASSVYRQGNFVDLCLGPHVPSTGYIKAFKLLNIASAVYKHDESKTLVRIYGTAFPDEKLLKQYLNNLEEAKRRDHRRIIAEMDLAVFNSEWAPGFPLYTQYGQTIRKELLSYMDSMNRKNGWFDVWTPHVFRDTIWKQSGHYAKYRPNMYLFTLPDGDSYGIKPMNCPGHIAIFSRRKYSYRDLPVRYSEPGTVYRYEKSGEVGGLTRPRAFTQDDGHAFLRMDQIGDEIRTLLTMVKDVFTILFGNIELSFDLSVIDRDHPENYLVSYVCRNCGYRIEGARGTDIECPVCHSHDLEPDLSVWDNATEQLRDALKSMGIEYKEYPGEAAFYGPKIDVHVKDAIGRMWQLSTIQLDFFMPVNFGLTYTNSEGKEDRVVMIHRAIYGSYERVMAILLEHYAGKLPTWLTPIQTYVVPISSNFDEYARHVHEELIRHGIRSEIDTSQETVSKKIKLIHPYRPAYIIVVGSKEMETNSVTARNREGKSKTYSLSEFIDVVKKEIEQRKVDQAF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_SALAR
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENAAPKEE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MNME_LEPBP
Sequence: MIDTIAALSTAQGPGAIGILRVSGSLVMPIALAVLEKNQKPLTETFLQNQKRSAIFCDFVENGKPLDQIVFFYFPAPNSYTGEDLAEFHLHGNPLLLKRALHVLFEKGARPAQKGEFTKRAYMNGKINLSGAEAISRLIEARSKYELELAQKNVFGEITKLSSKIRSDLISLKAECEAEIDFSTEDLTFESLEERKNRMVALKNLCSKLIKDSERAESYILQSTVVLYGEPNTGKSSLMNLLIGKDRSIISDVPGTTRDYIAEELSLDGIPIRLVDTAGIRDTTDNIEQMGIERSKREADSANVKLFLIDTSLPFEKQSFLLKHKDRLFGSLIVANKIDSKHPSWHTESIHDIQEEFQLTISEISCKTKQGIPELLELLKSKLTSKDDTEDLVLLEDRQRYHIQKIESCLSEAIQLMENNAPAEIYIQEINVALHEIGQVNGVVENEEILGRIFSKFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_BRUMB
Sequence: MEIGIAHYLTVSAILFTLGVFGIFLNRKNVIVILMSIELILLSVNLNFVAFSSQLGDLVGQVFALFVLTVAAAEAAIGLAILVVFFRNRGSIAVEDVNVMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KGUA_NITEU
Sequence: MSCLFVISAPSGAGKTSVIRTLLQTDINLTLSISYTTRPPRRDEKNGHDYFFVDHATFKDMQARGEFLESAEVHGNLYGTSRKWIEETMAAEQDVLLEIDCQGAQQIRTVYPQAASIFILPPSMEALKQRLEQRGQDENKVIERRLAAARSEISHVNRFDYVVVNHELETAARDVASIVQAERLKTIRQLVRQRSLIAEFS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_STRU0
Sequence: MANQTIIDTVMKTVSPVIEPPYELVDVEYEKMGSDYILSVFVDKEGGISVEDTVTLTELISPLLDAIHPDPFPEQYMLEVSSPGLERPLKTPEALTKAIGSYVNVSLYKAIDKVKVFQGDLVAFDGDTLTIHYLDKTRQKTVEIPYQTVAKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_STRGG
Sequence: MTPPASAPRVITVVGPTAAGKSDLGVFLAQRLGGEVINADSMQLYRGMDIGTAKLTLPEREGVPHRLLDIWDVTETASVAEYQRLARREIDRLLAEGRTPILVGGSGLYVKGAIDALEFPGTDPEVRARLEAELAERGSGVLHERLAAADPDAARSILASNGRRIVRALEVIEITGKPFTANLPGDEPVYDAVQIGVDVERPELDERIARRVDRMWDAGLVDEVRALEAAGLREGLTASRALGYQQILAVLAGECTEDDARAETVRATKRFARRQDSWFRRDARVVWLGGGHRDRGELPHRALTLVERAVTA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GREA_LIMF3
Sequence: MAEEKSFPMTADGKAKLEQELEDLRLVRRPEVINRIKIARSYGDLSENSEYESAKDEQAFVEGRISQIETMLQYAVIIDNEDVAADEVSMGREITFQELPDEEPESYTIVGESESDPLSGKISNESPMAKGLLGHKVGDTVEIEIPNGSMKVKILSVK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: YBJL_SALPK
Sequence: MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSVQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGIASTQLSSALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMITFQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGISNGLGAVGGQMLIAGLVVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIVIIWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPR_ECODH
Sequence: MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3G_BOTFB
Sequence: MSRVANNRDWADDEDLEDSNELPQSTTTTNKDGTQTIVTWRFNDDGKKVKTTRRIRFTKVKEIVNPRVAERKSWGKFGLSQKDAAGPASDTTSVGENIIFRPSTNWRKDAKEEVSDAGAMKNKLKDKQVKCRICSGEHFTAKCPFKGTMAPLGEEGAVDVAAGHADTPEGPGGLGAGKSSYVPPHLRNGGTAGGERMGGGKFERDDLATLRVTNVSEMAEEQELRDMFERFGRVTRVFLAKDRETGLAKGFAFISFQERSDAAKACEKMDGYGFKHLILRVEFAKKAS
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit homolog, eIF3 p33 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_CAMJE
Sequence: MRHLITTKDFNKVEIMELFKEASDFLDEKPRTFLEGKSITTIFFENSTRTLSSFESAARRLGARVLRLDVSRSSSSKGETLYDTAANLDAMSPNAIVVRHANSGVPLILAKHMHCPVVNGGDGKHAHPTQALLDLFTIYNHFQGNVEGKKICIVGDIKNSRVAASNIELLSRFNLDITLVAPPHFMPNTHLKKHYKLDENIIANSDIIMSLRTQTERHNKTVYASLKDYANDFCIQKSLVKDKKLILLHPGPVNRNIDISDEMMSNERTLVLKQVKNGVAIRMAVLKKLILENEG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ERCC1_HUMAN
Sequence: MDPGKDKEGVPQPSGPPARKKFVIPLDEDEVPPGVAKPLFRSTQSLPTVDTSAQAAPQTYAEYAISQPLEGAGATCPTGSEPLAGETPNQALKPGAKSNSIIVSPRQRGNPVLKFVRNVPWEFGDVIPDYVLGQSTCALFLSLRYHNLHPDYIHGRLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWSPEEAGRYLETYKAYEQKPADLLMEKLEQDFVSRVTECLTTVKSVNKTDSQTLLTTFGSLEQLIAASREDLALCPGLGPQKARRLFDVLHEPFLKVP
What is the function of this protein?
Not functional in the nucleotide excision repair pathway.
What are the official names of this protein?
DNA excision repair protein ERCC-1.
What is the protein family that this protein belongs to?
Belongs to the ERCC1/RAD10/SWI10 family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus. SUBCELLULAR LOCATION: [Isoform 4]: Nucleus.
Protein: RL3_MESHJ
Sequence: MKGILGKKVGMSQLFTTEGIAIPVSIIEVPENIVTKIITKEKNSYDAIQLAAFDKKQSRFLKPEIGHFAKANTKPKRFIKEFRDFQGYKLGQTVDVSIFSPGEFVDVTGTSKGKGFAGTIKRYNQAIGPRSHGGGGGSKPIRQTGSLGDISGNKVVKGMTMPGRLGHEKVTKQSLEIIKVDKENNLLVLKGSVPGPKKSFLVIKSAIKKPNPKNPVSLFVPNSDKEVKNE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DEOB_BACCQ
Sequence: MNKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTSADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFEKLKEDDLLLITADHGNDPVHHGTDHTREYVPLLAYSPSMKEGGKELPLRQTFADIGATVAENFGVKMPEYGTSFLNELKK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_LISMO
Sequence: MTNHEQVLTDYLAAFIEELVQAGVKEAIISPGSRSTPLALMMAEHPILKIYVDVDERSAGFFALGLAKASKRPVVLLCTSGTAAANYFPAVAEANLSQIPLIVLTADRPHELRNVGAPQAMDQLHLYGSHVKDFTDMALPENSEEMLRYAKWHGSRAVDIAMKTPRGPVHLNFPLREPLVPILEPSPFTATGKKHHHVHIYYTHEVLDDSSIQKMVTECTGKKGVFVVGPIDKKELEQPMVDLAKKLGWPILADPLSGLRSYGALDEVVIDQYDAFLKEAEIMDKLTPEVVIRFGSMPVSKPLKNWLEQLSDIRFYVVDPGAAWKDPIKAVTDMIHCDERFLLDIMQQNMPDDAKDAAWLSRWTSYNKVAREIVLAEMANTTILEEGKIVAELRRLLPEKAGLFIGNSMPIRDVDTYFSQIDKKIKMLANRGANGIDGVVSSALGASVVFQPMFLLIGDLSFYHDMNGLLMAKKYKMNLTIVIVNNDGGGIFSFLPQANEPKYFESLFGTSTELDFRFAAAFYDADYHETQSVDELEEAIDKASYHKGLDIIEVKTNRHENKANHQALWAKIADALKALN
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.