PharMolix/UniProtQA huggingface dataset:
Protein: PSAC_ILLOL
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIAPAPRTEDCVGCKRCESACPTDFLSVRVYLWYETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: LPXA_CHLPD
Sequence: MNTIHATAIIDPGVTLGDKVTIGPYTVIEDDVEIGEGTRIGPHVHIASGARIGSACRIHAGAVLATEPQDLKYAGEKTQLIVGDRTVIRECVTLNRGTKASGRTVVGSDTLVMSYVHAGHDCVIGNHVVIANSVQFGGHCEVGDYAVIGGLTGVHQFVRIGRYSMVGGIARASLDVPPFVMAGGHASFRYEGLNSLGLKRRGFTAEKISMIKDVYRIIFQSGLLLSNALEKVRTDFPAEPEIVEILRFFDSGTHGRKFLRPFNS
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y164_LEUCK
Sequence: MHNQKKNQGFSVKSVVATGIGAAVFFVLMKFIAIPTGVPNTTINVAEGWLALIAGLFGPVVGLLVGLIGHTLNDAVTYGAPWWSWVIADGVFGLLLGFGKKYLALEYGELTTKKLVQFNVWQAVSNVLVWVIIAPLGDIIIYKEAAQKVFLQGAVTTVVNTISVAIIGSLLLVAYVKSRPKKSSLRSE
What are the official names of this protein?
UPF0397 protein LCK_00164.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTH_ANAMF
Sequence: MLLLVGLGNPGKQYEFTRHNVGFVVADTVARDFDFPEFSSKYDALVSVGNVGLHRAMIVKPATFMNRSGAAVLKAASMHKIPAEQITVFHDDADLQHGVVKVKQGGGNAGHNGLRSIDAAIGCQYWRVRLGVGRPDAGSLSGHVLSDFHDFDSVQQLAHKISANLTELLDGNVNGFISKIRCDHAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_BURTA
Sequence: MTTILQINSAARSQGAQSTMLADELTAKLQQGNPGATVKVRSLLADALPHLDDAVLGAFFTPAEQRSAEQNAIVAKSDALIDELRSADVIVIGAPMYNFGVSSQLKTYFDWIARAGVTFRYTAQGPEGLLKGKKVYVVSARGGKHVGMPTDSQTPFLTTFLGFIGMTDVTFVYAEGLALGPDAASEALASAREAIAAV
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RS13_XANC8
Sequence: MARIAGVNLPAQKHVWVGLQSIYGIGRTRSKKLCESAGVTSTTKIRDLSEPEIERLRAEVGKYVVEGDLRREIGIAIKRLMDLGCYRGLRHRRGLPLRGQRTRTNARTRKGPRKAIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: P4HA1_CHICK
Sequence: HTDFFTSIGHMTDLINTEKDLVISKLKDYIKAEESKLEQIKKWAEKLDKLTDTATKDPEGFLGHPANAFKLMKRLNTEWGELESLVLKDMSDGFISNMTIQRQFFPNDEDQTGARKALLRLQDTYNLDTDTLSRGNLPGVKHKSFLTAEDCFELGKIRYTEADYYHTELWMEQALKQLDEGEVSSADKVYILDYLSYAVYQQGDLSKAMMLTKRLLELDPEHQRANGNMKYFEYIMAKEKEANKSSTDAEDQTDKETEVKKKDYLPERRKYEMLCRGEGLKMTPRRQKRLFCRYYDGNRNPRYILGPVKQEDEWDKPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPVVSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
What are the official names of this protein?
Prolyl 4-hydroxylase subunit alpha-1, 4-PH alpha-1, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: LDHA_RHIOR
Sequence: MVLHSKVAIVGAGAVGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGSAEEAGQADIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVDILTHIAKTLSGLPPNQVIGSGTYLDTTRLRVHLGDVFDVNPQSVHAFVLGEHGDSQMIAWEAASIGGQPLTSFPEFAKLDKTAISKAISGKAMEIIRLKGATFYGIGACAADLVHTIMLNRKSVHPVSVYVEKYGATFSMPAKLGWRGVEQIYEVPLTEEEEALLVKSVEALKSVEYSSTKVPEKKVHATSFSKSSC
What is the function of this protein?
Converts pyruvate to lactate.
What are the official names of this protein?
L-lactate dehydrogenase A, L-LDH A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDUI_BACLD
Sequence: MENRYSVHPEQAKRFTTAELREHFLIESLFVENKLNMFYSHEDRVVIGGAVPVKESIALDAGDFLKTDYFLERREIGIVNVGKPGAVKVGDEEYVLEHKDFLYIGLGNKDVFFSSLNEGGAKFYFISATAHQKYPVQKASLSELPYDHLGEEASSNVRNLYKVIHADGIQSCQLMMGITFLEPNNTWNTMPAHVHDRRMEVYLYLDLAEDAKVFHFMGEPTETRHLVVGNEQAVISPAWSVHSGSGTSNYCFIWAMAGENYTFKDMDAVPMNVIR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: OPGC_SALPC
Sequence: MSSVPAPREYFLDSIRAWLMLLGIPFHISLIYSTHSWHVNSATPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPLKRWWKVRVERVGIPMLTAIPLLTLPQFILLQYVKEKTENWPTLSAYEKYNTLAWELISHLWFLLVLVILTTVSIGIFTWFQKRQETSKPRPAAISLVRLSLIFFLLGMAYAAIRRIIFIVYPAILSDGMFNFIVMQTLFYVPFFILGALAFIHPDLKARFTTPSRGCTLGAAVAFIAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHISSNLIGFLCGLIFVMGIALILYEIHLRIPLLKFLFSGKPPVKQESRAAIG
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF5A4_SOLLC
Sequence: MSDEEHHFESKADAGASKTYPQQAGTIRKNGYIVIKGRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNAKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDGFVSLLTENGNTKDDLRLPTDDTLLNQVKGGFEEGKDLVLSVMSAMGEEQICAVKDIGTKT
What is the function of this protein?
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-4, eIF-5A-4.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
Protein: YKP1_KLULA
Sequence: MSYIDYLAYTGNTTFYDRFDGDLTSEHRIKCIINGCLINIMFSIRTIKEFPEEIKICQAAVSKFLTCGYVNDYLIEKYPPFYLWHKRFCDYDIYKMLMEKHPKLNYTVAKAAIMQRYNDLYFSFDFQPEEELIMTAALTENTEIYEDQINKAKKLGYCYSYLDYDNYCIKEEPGIEEIPDIEPKFNPFYVYVESGSKMEDVEYAVVNLVEEFKYLQMVYDMSKI
What is the function of this protein?
The presence of the two linear plasmids, termed pGKL1 and pGKL2, in strains of Kluyveromyces lactis confers the killer phenotype to the host cell, by promoting the secretion of a toxin able to inhibit the growth of sensitive strains.
What are the official names of this protein?
Uncharacterized killer plasmid pGKl-2 protein 1.
Protein: ALBA_PYRHO
Sequence: MTEEHVVYIGKKPVMNYVLAVITQFHEGAKEVSIKARGRAISRAVDVAEIVRNRFLKDDVDVKEIKIGTEELPTADGRTTNTSTIEIVLARKT
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  However, it does not significantly compact DNA.  Binds rRNA and mRNA in vivo.  May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
What are the official names of this protein?
DNA/RNA-binding protein Alba.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: FTSW_FRAST
Sequence: MLYRLKLLLSGQNTKKERVRAKLEIDISIVFVMLGLLIFGWVMVTSASMVVALDDYNNPYFYSIRQGFFAVIAIFLFLLALLVPTKNYEKNYNAFFFIMLIVLVAVLVPGVGKSVNGARRWIPLIIINIQVAELAKLLAIIFFSGYIAENLPKMTNFKEGILTPITLLGCIAVLLLMQPDFGSTVVISICVMGMLFVSGNKVRWYGLLIGAMLIMATMLVIISPYRMHRITGFLHPWENANGSGYQLVQALIGFGRGGWFGDGLGNGVQKQFFLPEAHTDFITSVIAEEIGVIGLMILLMVYLFIVFRAMNIAKMAFELKRYYQAFLSYGISFWIGFQVFVNIGVNTGLLPTKGLTLPLISYGGSSLLIMCFTLGILVRVDFENKLLADTINPKYIYKKVRK
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: PPLA_PIG
Sequence: MDKVQYLTRSAIRRASTIEMPQQARQNLQNLFINFCLILICLLLICIIVMLL
What is the function of this protein?
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+).  Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2.  Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle.  The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.  ATP2A2 inhibition is alleviated by PLN phosphorylation.  Controls intracellular Ca(2+) levels in elongated spermatids.  May play a role in germ cell differentiation.
What are the official names of this protein?
Cardiac phospholamban, PLB.
What is the protein family that this protein belongs to?
Belongs to the phospholamban family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Sarcoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Membrane; Single-pass membrane protein. Note=Colocalizes with HAX1 at the endoplasmic reticulum. Colocalizes with DMPK a the sarcoplasmic reticulum.
Protein: ISPE_CORDI
Sequence: MTSYAITAVASSKVNLHLGVGNARDDGYHELVTVFQSLSLHDTITVTPAADDMHDAEDQGIVATLSVSGDSAQAVPTDATNLAWQAAEKMYQAHRRNGGAPAKRVHIAIDKGIPVAGGMAGGSADAAATLAAMAQYLGNTNTEQEILSIAAELGSDVPFTYLGDTRLGTGRGEQLVPVLSRGTYHWALAFSAQGLSTPEVFRKIDQMDRQPHLDVTALNAALITGDPHKVAAHLHNDLQAAALSLRPELRTILEQGRAAGALAGIVSGSGPTCAFLCEDAETAQAVAAELSVHYRTAVATGPVRGAHVKGH
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SUCC_PARL1
Sequence: MNIHEYQAKAVLAKYGVPVPSGHAAFTPEEAVAKAKELGGPVWVVKAQIHAGGRGKAGGVKVVKSLDDVKKEATRLIGSTLVTHQTGPDGKEVNRLYIEDGSSISRELYLSILVDRATSRVSFIVSTEGGMDIEEVAKKTPEKILSFSVDPASGISGFHGRKVAYALGLEGDQVKQGVALIEKLYKAFVTEDMSMLEINPLVVTGEGNLLCLDAKVNFDSNALYRHKDIVELRDLTEEDPAEVEASKYDLNYIKLDGKIGCMVNGAGLAMATMDIIKLYGSEPANFLDVGGGATKEKVTAAFKIILSDPSVEGILVNIFGGIMRCDIIAEGVIAAAKEVSLSVPLVVRLEGTNVDLGKKIMAESGLPIISADNLADAAEKIVKAVKEAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PANB_SACS2
Sequence: MKKVTIRDFIKKKSMKEKITMLTAYDYPTAKIISNTTLDSILVGDSLGMVVLGYTNTLNVTMRDMISHTRAVARANPPQLIVSDMPFLSYEIDVKSAVKNAGLLVKAGSDAVKLEGGEEIKDIIRAIVKAGIPVMGHIGLTPQRFLRLGGFRTIGKTKQEEEQLIKDSLELEDAGVFSIVIENTYVDIAKRITEKLNVPTICIGAGPYCDGQVLVIHDLLGLSEVTPYFAKSYVNLKEIISSAINQYIIDVKTNKFPEKQHYKERES
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH109_SHEON
Sequence: MHNIHRRHFLKAAGAVTAGLVTANIALNANASSVAPKPSSGKSVIGLIAPKMEVVRVGFIGVGERGFSHVEQFCHLEGVELKAICDTHQAVVDRAVEHIVKQKRPKPAVYTGNDLSYRELLNRDDIDIVIISTPWEWHAPMAIDTMESGKHAFVEVPLALTVEECWQIIDTAERTQKNCMMMENVNYGREELMVLNMVRQGLFGELLHGEAAYIHELRWQMKEINHKTGSWRTYWHTKRNGNLYPTHGLGPVSQYMNINRGDRFDYLTSMSSPALGRALYAKREFPADHERNQLKYINGDMSTSLIKTVKGRTIMVQHDTTTPRPYSRHNLIQGTNGVFAGFPNRIAVENDGFGTSYHKWDTDMQKWYDKYDHPLWQRIGKEAEINGGHGGMDFVMLWRMVYCLRNGEALDQDVYDGASWSVVNILSEQSLNNRSNSVNFPDFTRGAWEHAKPLGIVGA
What is the function of this protein?
Glycosidase that has specific alpha-N-acetylgalactosaminidase activity.
What are the official names of this protein?
Alpha-N-acetylgalactosaminidase, Glycosyl hydrolase family 109 protein.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: RECR_MYCS2
Sequence: MFEGPVQDLIDELGKLPGIGPKSAQRIAFHLLSVEPPDIDRLTAVLGRIRDGVTFCSVCGNVSDEERCRICSDPRRDASLVCVVEEPKDVQAVERTREFRGRYHVLGGALDPLSGIGPEQLRIRELLNRIGERVEGVDVAEVIIATDPNTEGEATATYLVRMLRDIPGLTVTRIASGLPMGGDLEFADELTLGRALAGRRAMV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MDTG_ECO81
Sequence: MSPCENDPPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQISN
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_CAEBR
Sequence: MKINNSLLNFVNGMLVTLPSSKTLTLSWNFGSMLGMVLVFQIVTGTFLAFYYTPDSLMAFSTVQYIMYEVNFGWIFRIFHFNGASLFFIFLYLHIFKGLFFMSYRLKKVWMSGLTIYLLVMMEAFMGYVLVWAQMSFWAAVVITSLLSVIPIWGPTIVTWIWSGFGVTGATLKFFFVLHFLLPWAILFIVLGHLIFLHSTGSTSSLYCHGDYDKVCFSPEYIGKDAYNIVVWLVFIVLSLIYPFNLGDAEMFIEADPMMSPVHIVPEWYFLFAYAILRAIPNKVLGVIALLMSIVTFYFFALVNNYTSCLTKLNKFLVFLFIISSVILSWLGQCMVEDPFTVLSPLFSVIYFGLAYLLLGIFMTSKLLFK
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SSRA_MOUSE
Sequence: MRLLPRLLLLFLLAFPAAVLLRGGPGGSLALAQDPTEDEEIVEDSIIEDEDDEAEVEEDEPTDLAEDKEEEDVSSEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTVIEREDGLDGETIFMYMFLAGLGLLVVVGLHQLLESRKRKRPIQKVEMGTSSQNDVDMSWIPQETLNQINKASPRRQPRKRAQKRSVGSDE
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.  May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
What are the official names of this protein?
Translocon-associated protein subunit alpha, TRAP-alpha, Signal sequence receptor subunit alpha, SSR-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAP-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: BIOF_BURP0
Sequence: MNPLATLEQGLADIDAQGLRRCRRVADTACGAHMTVDGRAIIGFASNDYLGLAAHPRLVEAFAEGARRYGSGSGGSHLLGGHSRAHATLEDELAAFSGGFSDAPRALYFSTGYMANLAALTALAGRGATIFSDALNHASLIDGARLSRANVQIYPHGDADALDARLRACDAPTKLIVSDTVFSMDGDVAPLARLVALAETHGAWLVVDDAHGFGVLGPQGRGALAAHGLRSPNLVYVGTLGKAAGVAGAFVVAHETVIEWLVQRARSYIFTTAAPPSVACAVSASLAVIASDEGDARRAHLGALIKRTRAILRATHWQPVDSHTAVQPLVIGSNEATLAAMAALDAQGLWVPAIRPPTVPAGTSRLRISLSAAHSFDDLARLEAALVTPIGAAA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: BPHA_ASPNC
Sequence: MLALLLSPYGAYLGLALLVLYYLLPYLKRAHLRDIPAPGLAAFTNFWLLLQTRRGHRFVVVDNAHKKYGKLVRIAPRHTSIADDGAIQAVYGHGNGFLKSDFYDAFVSIHRGLFNTRDRAEHTRKRKTVSHTFSMKSIGQFEQYIHGNIELFVKQWNRMADTQRNPKTGFASLDALNWFNYLAFDIIGDLAFGAPFGMLDKGKDFAEMRKTPDSPPSYVQAVEVLNRRGEVSATLGCYPALKPFAKYLPDSFFRDGIQAVEDLAGIAVARVNERLRPEVMANNTRVDLLARLMEGKDSNGEKLGRAELTAEALTQLIAGSDTTSNTSCAILYWCMRTPGVIEKLHKVLDEAIPQDVDVPTHAMVKDIPYLQWVIWETMRIHSTSAMGLPREIPAGNPPVTISGHTFYPGDVVSVPSYTIHRSKEIWGPDAEQFVPERWDPARLTPRQKAAFIPFSTGPRACVGRNVAEMELLVICGTVFRLFEFEMQQEGPMETREGFLRKPLGLQVGMKRRQPGSA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the benzoic acid degradation pathway also known as the protocatechuic acid pathway (PubMed:11594739, Ref. 5).  Benzoic acid debradation begins with the conversion of benzoic acid into 4-hydroxybenzoic acid through hydroxylation by the benzoate-4-monooxygenase bphA, and its partner NADPH-cytochrome P450 reductase cprA which act as a mediator in electron donation from NADPH (PubMed:11594739).  4-Hydroxybenzoic acid is then converted into 3,4-dihydroxybenzoic acid (also called protocatechuic acid) by the p-hydroxybenzoate-m-hydroxylase phhA (Ref. 5).  Protocatechuic acid is converted into 3-carboxy-cis,cis-muconic acid by the intradiol ring-cleavage dioxygenase prcA, which is further metabolized through the 3-oxoadipate pathway to finally enter the tricarboxylic acid cycle (TCA) (Ref. 5).
What are the official names of this protein?
Benzoate 4-monooxygenase bphA, Benzoate-para-hydroxylase A, BpH, Cytochrome P450 monooxygenase cyp53A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RNPA_MARSD
Sequence: MSRLSWKKEHKLLRKPEFDLCYEQGKKLFTKSFILFVLCHGSGPSGVRLGLTVSRKKGPAVVRNRIKRVLRSYFRINQEIFQVRADIIIVPKRALDGKTITYALAEKELLPMVGKINKLSCGGE
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: SIGK_MYCBP
Sequence: MTGPPRLSSDLDALLRRVAGHDQAAFAEFYDHTKSRVYGLVMRVLRDTGYSEETTQEIYLEVWRNASEFDSAKGSALAWLLTMAHRRAVDRVRCEQAGNQREVRYGAANVDPASDVVADLAIAGDERRRVTECLKALTDTQRQCIELAYYGGLTYVEVSRRLAANLSTIKSRMRDALRSLRNCLDVS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis.  Sigma-K controls genes such as mpb70 and mpb83.  However, in strains with the start codon mutation (AUA), there is a decrease in SigK expression, thus affecting SigK-regulated genes expression as well.
What are the official names of this protein?
ECF RNA polymerase sigma factor SigK, ECF sigma factor SigK, Alternative RNA polymerase sigma factor SigK, RNA polymerase sigma-K factor, Sigma-K factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.