PharMolix/UniProtQA huggingface dataset:
Protein: DADD_METKA
Sequence: MRLAILGGIAVTPERVIEDAGILIDEDGRISFVDTREQLEECEDWEDEIELGEKDVIMPGLINTHTHGPMTLFRGVADDMPLMKWLREEIWPLEERLDAEKCRWGAALAAMEALKSGTTCLADMYFFMDAVAEAYAEVGIRAVISHGMIDLGEEDKREEELKESKRVYRKCQGMEGLIEFSLGPHAPYTCSEELLKEVRRLADEWGVKIQIHVAETEDEVKEVKRKHGKRPVEYLDEIGLLGDDVIAAHCVWLDDKEIEILSKRGVIVSHNPISNMKLASGISPVPEMLERGVNVTIGTDGCASNNNLDMLEEIKVAALLHKVNKMDPSATEMLEILRMATVRAGTVFSSEKIGAIEEGYAADLVVLDGSSPRLNPNHNPISNIVYSASGSDVKHVFVAGELVVKNGKLVKADEQEILENSTECAEQLTSS
What is the function of this protein?
Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs.  Can also deaminate adenosine.  The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
What are the official names of this protein?
5'-deoxyadenosine deaminase, 5'-dA deaminase, 5'-methylthioadenosine deaminase, MTA deaminase, Adenosine deaminase, S-adenosylhomocysteine deaminase, SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: NTPPA_STAMF
Sequence: MKILVLASSSQRRIELLRKLGADFIVIPPRITERIYDDPAKTVLENAFSKANYALVYAPENSIIIGMDTVIFSHELGVIGKPTTIEEATHILKLLRGKWHSVYTGVYIIEKNNLKYKSFIEETRVKMRNFSDEELTLYISSLEPLMKAGGYAIQGLGALLIETIVGDYYNVVGIPITKLYITLKKYFGVDLLREAVRKRVVGKTRTI
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_SALSV
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: PARC_STRP8
Sequence: MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRILYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGIIQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVRVNNKVPGIVEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTDLQVNYNFNMVAIDHFTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALIRSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLSAIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTRGGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELTDLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPWRTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGVKGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTKPHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERTSNGSFISDTISDQEVLVARTR
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GPR39_PIG
Sequence: MASPSRPGNDCSHVIDHSHVPEFEVATWIKITLILLFLVIFVVGILGNSVTIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPVEFYSIIWNPLTTPSYTVSCKLHSFLFETCSYATLLHVLTLSFERYIAICHPFRYKAMSGPCQVKLLIGFVWVTSTLVALPLLFAMGVEYPLVDVPSHRGLSCNRSRNHHSEHPETSNMSVCTNLSSRWTVFQSSIFGAFIIYLVVLVSVAFMCWSMMQALQRSKQGTLAAKGQQLQLRKSESEESRSARRQTIIFLRLIVVTLAICWMPNQIRRMMAAAKPKQDWTKAYFKAYMILLPFSDTFFYLSSVVNPLLYNVSSQQFRSVFAQVLRCRLTLPHANQDKRLRAQAASTMDSARSVHRPLIFLASRSNSSARRTDKVFLSTSQSESEAKPQSKPQLLNHESPESDSVMKPANPATENGIQEHEV
What is the function of this protein?
Zn(2+) acts as an agonist.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins.  Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).
What are the official names of this protein?
G-protein coupled receptor 39.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRDB_LACP7
Sequence: MNTNVTIAGVTFKNPVTTASGTFGSGMEYSEFVDLNRLGAITTKGVSSVPWPGNPVPRIAETYGGMLNAIGLQNPGVDMFVERDLAFLKQFDTKVIVNVCGKSVKEYVEVVERLSEEAVDLLELNISCPNVKEGCIAFGQDPKMIAMIMDEIKRHAKQPVIVKLSPNVTDITEMAKAAEAGGADALSLINTLTGMKIDINHRAFAIANKTGGMSGPAVKPIAVRMVYQVANAVKLPIIGMGGIQNAEDALEFIMAGATVVAVGTANFINPYATVEVIEGIEEFMRKNQISDINDLIGCVK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_STRCL
Sequence: MTVRVAVAGASGYAGGEVVRLLLGHPAESWVALTAFSQAGQAVGHPHLGPVAGRVFEPISAQAPLAGHDVVFLALPPAQSAALAEEAGARVVDRNMGADFRLRDAGVWERFYGSPWRGCWPYGLPESPGAREALAGARRIAVPGCYPTAVTLALFPAVGAGLVDREVVTAVSGTSGAGRALKPHLLGAEVMGSVSPYAVGGTHRHTPEIAQNSTAVTDGEPVSVSFTPLLAPMPRGILATCSARLTPGTDARQVRAVYEKTYADEPFVSLLPEGVWPSTGAVLGSNQVQVQVAVDPAADRLVVVSAIDNLTKGTAGGALQSMNLALGLPETTGLPRTGLAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_YERPY
Sequence: MSLSVEAKAKIVADFGRGTNDTGSSEVQVALLTAQINHLQGHFSEHKKDHHSRRGLLRMVSTRRKLLDYLKRQDVARYASLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RECA_HELPG
Sequence: MAIDEDKQKAISLAIKQIDKVFGKGALVRLGDKQVEKIDAISTGSLGLDLALGIGGVPKGRIIEIYGPESSGKTTLSLHIIAECQKNGGVCAFIDAEHALDVHYAKRLGVDTQNLLVSQPDTGEQALEILETITRSGGIDLVVVDSVAALTPKAEIDGDMGDQHVGLQARLMSHALRKITGVLHKMNTTLIFINQIRMKIGMMGYGSPETTTGGNALKFYASVRIDIRRIASLKQNEQHIGNRAKAKVVKNKVAPPFREAEFDIMFGEGISKEGEIIDYGVKLDIVDKSGAWLSYQDKKLGQGRENAKALLKEDKALADEITLKIKESIGSNEEIMPLPDEPLEEME
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_STRP7
Sequence: MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL28_MESFL
Sequence: MARKDMLTGKSALSGNSRSHALNATKRKWNLNLQKVKVMDENGNVFTIKVSARTLRTLKKQNVVVA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: LPXA_SALAR
Sequence: MIDKSAFIHPTAIVEDGAVLGANVHIGPFCIVGPQVEIGEGTVLKSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSIDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGIVAIRNAYKLLYRSGKTLDDAKLEIAELAEKHPEVKAFTEFFERSTRGPIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_AGRVS
Sequence: MRPSGRKTDQMRKISFERNFSKHAEGSCLVKFGDTHVLCTASLEDRTPPWLRNTGKGWVTAEYGMLPRATGERIKREASSGKQSGRTQEIQRLIGRSLRAVVDLEALGERQISLDCDVIQADGGTRTASITGAWIALHDCLKWMESRNIIKVDRVLKDHVAAISCGIFAAQPVIDLDYLEDSAAETDANFVMTGTGGIVEIQGTAEGKPFSQEEFLTLLGLAQTGIAELVDLQKQAIAG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TRPB_YERP3
Sequence: MTTLNPYFGEFGGMYVPQILVPALKQLEDAFVSAQLDPEFQAAFQDLLKNYAGRPTALTLCQNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALACALLGLKCRIYMGAKDIERQSPNVFRMRLMGAEVIPVHSGSSTLKDACNEALRDWSGTYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEKEGRLPDAVLACVGGGSNAIGMFADFIDEPDVGLIGVEPAGLGIETGQHGAPLKHGKVGIYFGMKSPMMQTSDGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALDAFKTLSCKEGIIPALESSHALAHALKMIKADPDKEQILVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ZRAP_YERPS
Sequence: MNLNKTAIVTLLSLATLIGFGGSAIAQNAMGTHMNGDGTDMSHSQGKYSGKNSMANLTTEQQAIRQQVLNEFQASTADMRQQLTSKNYEYKALLTSKPVDEQKVLAVSKEIQTLRDSLYQRRVSMDTQLAKAGIAMTGNHGSRGGNHMGMAGGRGCR
What is the function of this protein?
Binds zinc.  Could be an important component of the zinc-balancing mechanism (By similarity).
What are the official names of this protein?
Zinc resistance-associated protein.
What is the protein family that this protein belongs to?
Belongs to the ZraP family.
What are the subcellular locations of this protein?
Periplasm.
Protein: QUEA_PROM1
Sequence: MLDQKDNLLSSYNYDLPKDLIAQSPTRSRHDAKLMIIKDGLDDSLNLVHAKVWDIKDILKPADLLVVNNTRVVKARLKIRLSGGGAGELLIMEPRGDGRWLCLGRPARRMRGGDQLWLDTSRDNSLILKVIDKDEKTGGRIIQFSNEFTSWTEMENLLDLCGEVPLPPYIDKDRSSGHEENYQTRFASKPGAIAAPTAGLHLSDELIENLKIRGIRIAQITLHVGLGTFRPLEKEDLSQLHLHSEWIEVTEETIKAITTCKEEGGKVFAVGTTSVRALEAAYLSGRGALKPYEGKVNLVIKPGFKFSVIDGLLTNFHLPKSSLLLLVSALIGRNRMLKLYKHAISNKYRFFSYGDAMLITPESVI
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_NATPD
Sequence: MTVVSVSMPESLLDRLDEFAEEHGYTGRSEVVREASRNLLGEFEDKKLEGRELMGVVTVVFDHETSSAEERMMQIRHDHEHTVVSNVHNHVGDHYCMELFILEGELDEISTFVGKVRATSDILSVDYSVVPLDDFEADLAH
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: HFQ_ECOLI
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Involved in the regulation of stress responses mediated by the sigma factors RpoS, sigma-E and sigma-32 (PubMed:17158661).  Binds with high specificity to tRNAs (PubMed:18230766).  Binds sRNA antitoxin RalA (PubMed:24748661).  In vitro, stimulates synthesis of long tails by poly(A) polymerase I (PubMed:10677490).  Required for RNA phage Qbeta replication (PubMed:805130).  Seems to play a role in persister cell formation; upon overexpression decreases persister cell formation while deletion increases persister formation (PubMed:19909729).
What are the official names of this protein?
RNA-binding protein Hfq, HF-1, Host factor-I protein, HF-I.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: HOATZ_DANRE
Sequence: MSEELDEEVLDGLTEVEKLYTVFHGASQEDVAYAKLFWNSLSLQPPIESRLVSSDIRQRLKVAKTPNTTNAAANQAPWSKRNEEIQQDAYLRQKQEEKQRYMEMAKNRDQIIALLKKQRDERIKKEMIAYKHKPKKGKLEEKRLAPKTLSSDVDEDQKEVQKLQ
What is the function of this protein?
May be required for motile ciliogenesis and flagellar genesis.
What are the official names of this protein?
Cilia- and flagella-associated protein HOATZ.
What is the protein family that this protein belongs to?
Belongs to the HOATZ family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium.
Protein: RL10_CALS4
Sequence: MGASREKKQQIVAEFKDKLSKAQTVIFTSFSGLTVEDETVLRRKFKEANSEYKVYKNTLMTIAARELGYGDDLIKYFEGPTSVAFGYEDPVAPAKILTEFMKDHKGLELKVGIVNGKIVSPQEIEALAKLPSREELLAKALGSMKAPITNLVFVLSGTLRSLVYALNAIKEKKQAEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PTC_MYCMS
Sequence: MNKVRHFIDTQDLSKKEIFEIFRLMKMLKEARYCGAVPELLKNKTLAMIFEEPSTRTRVSFEAAMTLLGGHAQYLKPGELHLGVRESLYDTTKVLSHMCDGIMCRALKNETVLNLAKYADVPVLNGLTDYNHPTQAICDVFTMLEYMPATKNLEYEDIKFEDIKVVFIGDRTNVCSSTMHITTKLGMNFVHISPKRYQSPQEWIDIANENIKQANSGSVLVTDDLEQVRGADIVYTDLWWWVDQEDEAEERVKAFKPTYQVTPELMEKAGKQALFMHCLPASRNVEVYDEVIDSDQSIAFEQAENRLTAQMGLLVYYLYPQIDKSSNAVKDYYRGKVEAFMEHQDRSWKQRYTYNNDYAETKNKK
What is the function of this protein?
Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine.  Is involved in the degradation pathway of the polyamine agmatine.
What are the official names of this protein?
Putrescine carbamoyltransferase, PTC, PTCase, Putrescine transcarbamoylase, Putrescine transcarbamylase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. PTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_BURMA
Sequence: MASKIETLKANLEAALGARAVSLVEAVGELTLVVKASDYLEVAKQLRDDRSLGFEQLIDLCGVDYQTYGDGAYDGPRFAAVLHLLSVANNWRLRVRVFASDDDLPIVPSVVDIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPQEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PHLC_PSEAE
Sequence: MTENWKFRRRTFLKHGAQAATLAGLSGLFPETLRRALAVEPDIRTGTIQDVQHVVILMQENRSFDHYFGHLNGVRGFNDPRALKRQDGKPVWYQNYKYEFSPYHWDTKVTSAQWVSSQNHEWSAFHAIWNQGRNDKWMAVQYPEAMGYFKRGDIPYYYALADAFTLCEAYHQSMMGPTNPNRLYHMSGRAAPSGDGKDVHIGNDMGDGTIGASGTVDWTTYPERLSAAGVDWRVYQEGGYRSSSLWYLYVDAYWKYRLQEQNNYDCNALAWFRNFKNAPRDSDLWQRAMLARGVDQLRKDVQENTLPQVSWIVAPYCYCEHPWWGPSFGEYYVTRVLEALTSNPEVWARTVFILNYDEGDGFYDHASAPVPPWKDGVGLSTVSTAGEIEVSSGLPIGLGHRVPLIAISPWSKGGKVSAEVFDHTSVLRFLERRFGVVEENISPWRRAVCGDLTSLFDFQGAGDTQVAPDLTNVPQSDARKEDAYWQQFYRPSPKYWSYEPKSLPGQEKGQRPTLAVPYQLHATLALDIAAGKLRLTLGNDGMSLPGNPQGHSAAVFQVQPREVGNPRFYTVTSYPVVQESGEELGRTLNDELDDLLDANGRYAFEVHGPNGFFREFHGNLHLAAQMARPEVSVTYQRNGNLQLNIRNLGRLPCSVTVTPNPAYTREGSRRYELEPNQAISEVWLLRSSQGWYDLSVTASNTEANYLRRLAGHVETGKPSRSDPLLDIAAT
What is the function of this protein?
Hydrolyzes sphingomyelin in addition to phosphatidylcholine.
What are the official names of this protein?
Hemolytic phospholipase C, Heat-labile hemolysin, PLC-H, Phosphatidylcholine cholinephosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the bacterial phospholipase C family.
Protein: AGOG_PYRAB
Sequence: MIARIIGEIGIEGARFIEENIDEQFKALRYLSKGIDSETFVKLVIANSLVSYQLTGKGEQWWWEFAKYFYGRDVKSIYLAYKEFLPNSRFNRRLIPQKLSRIRRVETFLSTLTEERIEEYYGDMSSLWGSIARALGVDKESKTVVFSVKMFGYAARIVLSTFNPYPMEIPIPEDSRIVKLTKKLTNEKPRKFWMKIARESGVPPLHIDSILWPLLGGASIDSAPPELRDKLAELIKIIR
What is the function of this protein?
DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
What are the official names of this protein?
N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, AGOG, DNA-(apurinic or apyrimidinic site) lyase, AP lyase.
What is the protein family that this protein belongs to?
Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
Protein: GALC_HUMAN
Sequence: MAEWLLSASWQRRAKAMTAAAGSAGRAAVPLLLCALLAPGGAYVLDDSDGLGREFDGIGAVSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYALDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYVNLQLTAYYVVTWIVGAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNYQGLQRVKIIASDNLWESISASMLLDAELFKVVDVIGAHYPGTHSAKDAKLTGKKLWSSEDFSTLNSDMGAGCWGRILNQNYINGYMTSTIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKTVGHLEKGGSYVALTDGLGNLTIIIETMSHKHSKCIRPFLPYFNVSQQFATFVLKGSFSEIPELQVWYTKLGKTSERFLFKQLDSLWLLDSDGSFTLSLHEDELFTLTTLTTGRKGSYPLPPKSQPFPSTYKDDFNVDYPFFSEAPNFADQTGVFEYFTNIEDPGEHHFTLRQVLNQRPITWAADASNTISIIGDYNWTNLTIKCDVYIETPDTGGVFIAGRVNKGGILIRSARGIFFWIFANGSYRVTGDLAGWIIYALGRVEVTAKKWYTLTLTIKGHFTSGMLNDKSLWTDIPVNFPKNGWAAIGTHSFEFAQFDNFLVEATR
What is the function of this protein?
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine (PubMed:8281145, PubMed:8399327).  Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon (PubMed:8281145, PubMed:8399327).
What are the official names of this protein?
Galactocerebrosidase, GALCERase, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 59 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: ASUE2_STRNS
Sequence: MSTHTARRAGATAGHDRDRGTEPGRTEFRRAMGLLPTGVAVVTVGSGEQTEAVTVGSVVSVSLDPALVLVSLGSTGRLVEAIDRAGGFAVNVLTTEQSDLSACFASHDRPHGRGAEERLGGVAGASGHVLLRDAVLSMECRTEHRYPGGDHVLFLGRVDELHTAEAAGSPLVHHRGAYTTLKDPC
What is the function of this protein?
Involved in the biosynthesis of the antibiotic asukamycin (PubMed:20522559, PubMed:23890006).  When flavin concentration is low, AsuE2 assists the protoasukamycin 4-monooxygenase AsuE1 by providing a reduced form of flavin, enhancing AsuE1 activity (PubMed:23890006).
What are the official names of this protein?
NADH-dependent FMN reductase AsuE2, Flavin reductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family.
Protein: HEM1_ENT38
Sequence: MTLLALGINHKTAPVALRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLHEALIRWLCEYHNLNEEELRTSVYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHLKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVKHMIIANRTRERAQVLADEVGAEVIALSDIDERLKDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVQAETIVEQESGEFMAWLRAQSASETIREYRGQAEQVRDDLTAKAMAALEQGGDPQVIMQDLAWKLTNRLIHAPTKSLQQAARNGDDERLTILRNSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HSLU_STAAC
Sequence: MDTAGIRLTPKEIVSKLNEYIVGQNDAKRKVAIALRNRYRRSLLDEESKQEISPKNILMIGPTGVGKTEIARRMAKVVGAPFIKVEATKFTEVGYVGRDVESMVRDLVDVSVRLVKAQKKSLVQDEATAKANEKLVKLLVPSMKKKASQTNNPLESLFGGAIPNFGQNNEDEEEPPTEEIKTKRSEIKRQLEEGKLEKEKVRIKVEQDPGALGMLGTNQNQQMQEMMNQLMPKKKVEREVAVETARKILADSYADELIDQESANQEALELAEQMGIIFIDEIDKVATNNHNSGQDVSRQGVQRDILPILEGSVIQTKYGTVNTEHMLFIGAGAFHVSKPSDLIPELQGRFPIRVELDSLSVEDFVRILTEPKLSLIKQYEALLQTEEVTVNFTDEAITRLAEIAYQVNQDTDNIGARRLHTILEKMLEDLSFEAPSMPNAVVDITPQYVDDKLKSISTNKDLSAFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.