PharMolix/UniProtQA huggingface dataset:
Protein: YBEY_DEIRA
Sequence: MIDLIARKRPPAGLRPALRASLSAAMQHFGGEEREVTVVLVGDPEIRALKLEHWGEDAATDVLSFPTWEPGDPFMPPHLGDIIISLDTAQRQAESRGHSLTREVALLASHGLTHLVGHDHPHAEGLGFEEGATGEDWQVFHDAWAAAQTGLPAGA
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_HISS2
Sequence: MAWIQLRLNSTNEKAEKISEYLEEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVIALFDAKTNMQQIVRLLQQKNHLDENTAYKIEQIEDKDWEREWMDNFHPMKFGKRLWICPSWREIPDENAINVMLDPGLAFGTGTHPTTALCLEWLDSLDLTGKTVIDFGCGSGILAIAALKLGAKSAVGIDIDPQAILASYNNAEQNGVAERLQLFLSEEKPTDLQADVVIANILAGPLKELYPIISNLVKPQGDLGLSGILSTQADSVCEAYQGKFTLDPITEREEWCRITGKLNSFV
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COG6_SCLS1
Sequence: MTTDYFTRKQSYSGFSDGADSPGSPLASRTNPLSSKVTSVLSASYADSDIRDALSLLDKRGIQNTAETRRQLRLDVHREVIESNGDIIREFGHVAEEASELMKQQEQMQAKQELLNAFNAHFVMSDDDIAMLTSTAEPVNDRFFSILSRAKKIQNDCEILLGTENQRLGLEIMEQTSKNINGAFQKLYRWIQREFKTLNLENPQISSSIRRALRVLAERPSLFQSCLDFFAEARENILSDGFYTALTGTTVGGDEDPSIKPIELVAHDPLRYVGDMLAWTHSATVGEREALEVLFISDGDEIAKGIQAGLDSEPWNRIAESEDEVGHFDGLKALNELVDRDVAGVARVLRQKIGQVIQSHEETIMAYKIANLLNFYRGTFQRLLGDDSVLLDSLATLEESALRQFRALMRDHITSLQAETQVAPPNLSPPDFLHEGLKQLTAIMKTYETSFTSPETREAGFEPILTEAFDPFMKGSENVAKDLSAPRSTIFTINCLLSARATLAPFDFTISRVSQIKDTIEEHAATLIDHQYIFFLEKSALQPLLQALSATTDIRDHPVFQPASLIQASQTLDDFLPSALMDAMENLKDLQNSMLVRQITEEAAEKFCDDFEKVEERLMKADEEREESLDEKDGEPHHVRALYPRTGGEIRVLLSIRIWNMFKTWRLEIT
What is the function of this protein?
Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking.  COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 6, COG complex subunit 6, Component of oligomeric Golgi complex 6.
What is the protein family that this protein belongs to?
Belongs to the COG6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: STHA_VIBVY
Sequence: MAHANHFDVIVIGSGPGGEGAAMGLTKAGLKVAVVEKESSVGGGCTHWGTIPSKALRHAVSRIIEFNSNPLFCKNNSSLHATFSTILGHAKSVIDKQTRLRQGFYDRNQCQLIFGTARFTDAHTISVTQNDGTEEVYTADKFVIATGSRPYQPADVDFNHERIYDSDSILSLKHDPRHIIIYGAGVIGCEYASIFRGLGVKTDLINTRDRLLAFLDNEVSDALSYHFWNSGVVIRNDETYERIEGTEDGVIVHLQSGKKMKADCLLYANGRTGNTDKLNLPAVGLQGDSRGQLKVDGNYQTEVEHVYAVGDVIGYPSLASAAYDQGRFVAQAITKGKADGYLIDDIPTGIYTIPEISSVGKTEQELTAAKVPYEVGRSSFKHLARAQIAGKDIGSLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGEANTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEGL_PORGI
Sequence: MKKEDLMRSGFATRAIHGGAIENAFGCLATPIYQTSTFVFDTAEQGGRRFAGEEDGYIYTRLGNPNCTQVEEKLAMLEGGEAAASASSGIGAISSAIWVCVKAGDHIVAGKTLYGCTFAFLTHGLSRYGVEVTLVDTRHPEEVEAAIRPNTKLVYLETPANPNMYLTDIKAVCDIAHKHEGVRVMVDNTYCTPYICRPLELGADIVVHSATKYLNGHGDVIAGFVVGKEDYIKEVKLVGVKDLTGANMSPFDAYLISRGMKTLQIRMEQHCRNAQTVAEFLEKHPAVEAVYFPGLPSFPQYELAKKQMALPGAMIAFEVKGGCEAGKKLMNNLHLCSLAVSLGDTETLIQHPASMTHSPYTPEERAASDISEGLVRLSVGLENVEDIIADLKHGLDSLI
What is the function of this protein?
Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia; methanethiol (methyl mercaptan) is considered to be one of the main causes of the oral malodor in periodontal disease and may also play a role in the pathogenicity of P. gingivalis in that disease (PubMed:11083813).  Is also able to catalyze the alpha,gamma-elimination of L-homocysteine (By similarity).
What are the official names of this protein?
L-methionine gamma-lyase, MGL, Homocysteine desulfhydrase, L-methionine-alpha-deamino-gamma-mercaptomethane-lyase, METase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.
Protein: RBFA_HALH5
Sequence: MSNVRANRVGEQMKKELSDIFMRELKDPRIEFVTVTGVDVTGDLQQANVYITVLGDDEQKEATLAGLSKAKGFIRSEIGKRIRLRKTPELFFHFDESIEYGNRIEKLLQDINRDGE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
Protein: CVC1_PSHV1
Sequence: MEAHFVAAAAHSAAFGDRVGGESPYLSHIVLSERCMVNFGVPTFLLASGNNFYAEVQIRFHGCLQCTQWRRVFSVYAPSSAIDRILLPDVSSGNCGRSAPFRIMYDSGNSWGGLFISVPVFCDPEKLTFDGYTAVAVRLAICGSADEFYEMLFTYDELAQPQTRFYADAGRFDALALQICEYHIPAAWPSRRKEEFLNLRGRLLELIAARGSTRQLDKVLRADSYITHEQPLVPDPPKEDEAASEAKKKEADDAMKKLKDAAAKVASSDANRQREPGDREQGVSAALLSTCSGMPGDHHAPQHAAVAGAVKAVASGLNSIVRGLSAAGGAAATSASQLADIRYTDALLAGLEPPGRNRGEPRPQRRVPDLESVVMDDGQSRHDRVIPASGLGGARAPASVEECLKALCAIISDPGTPPQSAWTFGPISIVTHSCYNSGSPILIVTYSDGGRRAYPPIVSGITALSEALLAAGASFPSDLNEDEKAELLRKAPCFARPMAADEAREYQKLFSVDSEQVFLFGLQARVTTAMITALTVAVARATDQAADNLLLNQIVSYDLAVRDDDDLPGGRGQRDRLAVAQYDGDRAAGHWPAKLASQAADLIAWFCVNLQTESFATFARSGVWKAILTSLVAEDTLHRLPFLAPFHSDPAIYMFDYFRFGAGNMSRVTGDPNVIRFKPALRTGLMDCEFISGAASPAHPWAVHKFLPGQFHSYLCVGLNSELEGLLIFPGGFGLRFDLGETLDEVWDKNLDRAVLDRYSRLANISGGPPRADRGADCAIADVGCAYPYLKSAPRAPSDFSTTSTSGHESVTILY
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.
What are the official names of this protein?
Capsid vertex component 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: NHAA2_SALTO
Sequence: MDATRRDLPPGSVVRRRTDRIADVLRAETTGGALLLAGAVIALIWANSPGAAGYDAMRSFTVGPAWLHLDLSLAAWAKDGLLAVFFFVAGLELKREFVTGELRQPRRAAVPIAAAVGGVLAPAAVYVLITAAAEADALRGWAIPAATDIAFALAVLAVIGRHLPPAVRVFLLTLAVVDDLIAIMIIAVFYTANLSVTPLLATALPLVAFAILLRRRVTSVWLLLPLALTTWALVHASGVHATVAGVLLALVVPARPHSQHEHTAAPSLLERFEHAIKPVSAGLAVPVFALMSAGVAIGGLGGLVSALTDPVAIGVIAGLVIGKPLGVIAVTWLVTRLTRTGLGNNLTWTHITGLSMLAGIGFTVSLLIGELSFAAGTERHDHVKIAIVTGSLIAAVLAAVILRLPNRAGSRGNDATTRDPDQTRVGTATQRTTPDHPTPAATDANQPARSPAP
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DYR_MESAU
Sequence: MVRPLNCIVAVSQNMGIGKNGDFPWPMLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPQGAHFLAKSLDDALKLIEQPELADKVDMVWIVGGSSVYKEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLEKYKLLPEYPGVLSEVQEEKGIKYKFEVYEKKG
What is the function of this protein?
Key enzyme in folate metabolism.  Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.  Binds its own mRNA (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: ILVD_BURP1
Sequence: MSYNRRSKNITQGVARSPNRSMYYALGYQKEDFDKPMIGIANGHSTITPCNAGLQRLSDAAVAAVKDAGANPQIFGTPTISDGMSMGTEGMKYSLVSREVIADCIETCVQGQWMDGVVVVGGCDKNMPGGMIALARINVPGIYVYGGTIRPGHWKGHDLTIVSSFEAVGEFTAGRMSQEDFEGVEKNACPTTGSCGGMYTANTMSSSFEALGMSLLYSSTMANPDQEKVDSAAESARVLVEAVKKDLKPRDIITKQSIENAVSVIMATGGSTNAVLHYLAIAHAAEIDWSIEDFERIRKRVPVICDLKPSGQYVATDLHAAGGIPQVMKLLLDAGLLHGDCMTITGRTLAEELKDVPSVPRADQKVIHPIDQALYKEGHLAILKGNLAEDGAVAKITGLKNPVITGPARVFDDEQSALAAILDDRIRAGDVVVLRYLGPQGGPGMPEMLAPTSAIIGKGLGESVGLITDGRFSGGTWGMVVGHVAPEAFVGGTIALVQEGDSITIDAHKLLLQLNVDDAELARRRVAWKQPAPRYTRGVLAKYAALARPANQGAVTG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ATPG_HAEIG
Sequence: MAGAKEIKTKIASVQSTQKITKAMEMVATSKMRKTQDRMAASRPYSETIRNVISHVSKASIGYKHPFLVEREVKKIGILVISTDRGMCGGLNVNLFKTILNQIKNWKEQNISTDLGLIGSKGISFFRSFGFNIKGQLSGLGDMPALEELIGVANTMFDAYRNGEIDAVYIAYNKFVNTMSQKPVVQQLVPLPESKDDHLNERQQTWDYLYEPEPKVLLDSLLVRYLESQIYQAVVDNLASEQAARMVAMKAATDNAGNLINDLRLVYNKARQASITNELNEIVAGAAAI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: G0S2_MOUSE
Sequence: MESVQELIPLAKEMMAQKPRGKLVKLYVLGSVLALFGVVLGLVETVCSPFTAASRLRDQEAAVVELREACEQQSLHKQALLAGGKAQEATLCSRALSLRQHAS
What is the function of this protein?
Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
What are the official names of this protein?
G0/G1 switch protein 2, G0S2-like protein.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ORF1_HAPV1
Sequence: MSHNDTPANNTNGIADVYADENPCEIAGEDNPPQPYSCFDGEDRAHDKTRIIKWLCYHPKGVPLARTVKALFPDDSEKRISERSYTSTDYNFVSRFLERTGYAVLDSEAGLIEASPTSRAFHLTLESKIPSEHTTNYAKDRAEACAYGMWSLNDVENARLLAKDFTTYLESIHDRRLMLENVDNPDMKLTMPYHTRFNDDRRKAEQWARYNSAWEAADDKYSSGVMVTLTTDPKRYDSIGEMLDGLMDAWQNLHETLNQRYLEGTRLDFIRALEFGGSEKSNHIGLPHLHVCVFGVPYIDHRWLKHYWSSKHAEIVHIHGMNKRGNDSWIMTSGTHAGKSVAGYLGKYLSKTFERIADDPDELREHYQSWSEGGDWANSELWKLALYWATGRQFWASSHDLKDDSRNFDTLQEVPGLGETKLDRLEAHGIQTLSDVRLASVDEIASIDGISESFAEKLKDLVGEPSEFDVFRFEFRGAARYEEMPASWSHARHLGVSACG
What are the official names of this protein?
Uncharacterized protein 1.
Protein: YMF3_YEAST
Sequence: MLSYYEHNTAFQTNNCNSGSNAATTYNSDANNDTIMNKRKNDHFEFDTHTFYQRSKRTKRDSVSTKFSVGSGCANLNNNNNNIIINNNNNNNNNNNNHNHNNSNNTATYNNIHYKKNIEICPLKPVSMHHTMNSRLLNESEFYSETEEYMIHGYFGNTNRDITGTSPTGSASIIQHQYHLLPSQSIIASQAPGTAMAALTNNNIANDYMDID
What are the official names of this protein?
Uncharacterized protein YML053C.
Protein: Y0170_DICDI
Sequence: MSLEQQDETVVEEETKTSFETNNSTANNTNNNTDNTYKEEILKSTESITRNDDKVDPTSATALEKDIINNGEYSGSSSSSGNNNINGSNNIKNIVIEKVEQLERVVVNNNNGDENNKDIHDSSNNTEDIDISKSHIIKYDKDEMSTISTIHYSDDESSKEKQDNINSNNNNNKNKNEQIINSENILDTPMTEASDQTTPSDTPPTLTNNTSSTTTTTTTNNTTTAATTTTNSRRKRNSLSTPSSEMDPVLDSTSENNTTRKTRGSRNSKKEPEELLLTPEQAKELSNKSKKWIYVPIIEAEAKKEEVLPAKRDRKQVFNENIFSSSRKSTTKGGEKKNDTASTTNTPIITAQQNTTPLSPTQTTTTTTTPTTTTAQQNTPAQTESKPPTTISINIKGSKSPKTTGGKQQKPTPPSPVVISQPVVPSTPVVATTKKTNSRSKRSTANNNSETTQTPEVVISAPTTTTAAITTPINITPSSDSATIQQLQQSISMLEDKIRLISSNNKVATEILNNTITTTTTTAATSAIKDEEIIENTELQTTFTKSSTLAPPSSERKYSNLYSDDEDDTEMVDVSVSIPIPIPIPTPTQTTTKKTTLSKKRKSNTSTIIPTTTIQQEQGQEQGQQQPPQQQQPPQQQQPPQQQQPPQQQPPQQSTSPSKTQQENTSSTTTTTTTTTTTTNTEDTTTVIDKKPKKKPRHSAPLIPQIKPRLPLNGGSSERAQRSSRGRMGKAMRDVVLTPVFKRCLDLLEELFEHQHSPPFLVAVDPYALGILDYFDVIKHPMDLGTIKASLIGGGYDTIDKFAEDCRLVFSNAKTYNPSTNPVHIMAQSLEDVFEKGFPKVLIEPPSPPPKNVDQEKIEKLSNDLKNVTKELEKFKKDDSNSINNNNNNNNNYNNNNNNNNNNSSSSSSRSSSRKSHSSGSSSSHRSGSSRSSRGSSSSSSSSSSSSSSSSSSSSSSSSNNKKYPKVTTEEKTKLGAEITQLPVDLLPSILQIIHNTNSLPEQKPGSEVVIDLMKFDDDILRRLSKFVEQYKNGEIPQHALPLSAPSSTHSSHSSSHDSSSNIREIEKLQKQLDRLGKGQQNSSSSSSSSSHSKRISKPISKARGRKVISTSSSNLNNSSNNINNNNNNINNYNNNNNYNNNNNNNLNNNNNNNINSNLNNNLNNNNNKDDIVIDGFKKENFSSIPEKDVETDISESSDSESDSESGSSDSSSSYSDSDFSDSDNDRRRNYNNSYNNNNNNNNNNNSSNNFNNQNNSYNNSNNNNNNNSSNNNNNNNNNNSNNNNSNNNNNNVNNNNNNHNNNNHNNNINNNNNNINNNTTQPSPSQQSTSLTNEPIKPPTILQTVKKPALPVTGSVASWSFDPTNNKESSSSSSTSSTSSTSNTTLTPIIQQSSLTHASSPISSSTFVSFSSSSSTPPTNNLSPPSPGLPNSPSINSPSSPSANNNNTDSAWNHFKAKNITLKQKEKERVLQEEVLRKEREEKEEELKKEEEKKRIEMEEIKRLAKEKEEREAEETRKQIESERAAAREAREKEKLNNSKGNMSFQYQMDVMASFEDNIDSSGSLLNLQLKPIEDPL
What are the official names of this protein?
Bromodomain-containing protein DDB_G0270170.
Protein: ZN157_HUMAN
Sequence: MPANGTSPQRFPALIPGEPGRSFEGSVSFEDVAVDFTRQEWHRLDPAQRTMHKDVMLETYSNLASVGLCVAKPEMIFKLERGEELWILEEESSGHGYSGSLSLLCGNGSVGDNALRHDNDLLHHQKIQTLDQNVEYNGCRKAFHEKTGFVRRKRTPRGDKNFECHECGKAYCRKSNLVEHLRIHTGERPYECGECAKTFSARSYLIAHQKTHTGERPFECNECGKSFGRKSQLILHTRTHTGERPYECTECGKTFSEKATLTIHQRTHTGEKPYECSECGKTFRVKISLTQHHRTHTGEKPYECGECGKNFRAKKSLNQHQRIHTGEKPYECGECGKFFRMKMTLNNHQRTHTGEKPYQCNECGKSFRVHSSLGIHQRIHTGEKPYECNECGNAFYVKARLIEHQRMHSGEKPYECSECGKIFSMKKSLCQHRRTHTGEKPYECSECGNAFYVKVRLIEHQRIHTGERPFECQECGKAFCRKAHLTEHQRTHIGWSWRCTMKKASH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 157, Zinc finger protein HZF22.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_CHLCV
Sequence: MVRATGSVASRRRRKRVLKQAKGFWGDRKGHFRQSRSSVMRAMAFNYMHRKDRKGDFRSLWIARLNVASRINGLSYSRLINGLKCAGIDLNRKMLSEMAIHNPMGFAEVANQAKKALEATI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: LSPA_BORRA
Sequence: MNINRNRLVSNLIFISILVFFDQWSKYLVVTYVRLGTEYLSFFGDLFKIIHVRNTGVLFSLGSNIDSSLKNLFFLIIPIIILVFVFSFSLKENNKVSRFALILILSGGIGNIIDRLFRPLGVVDFLDVKFFGIFGLQRWPTFNFADSYVVVGMIVFIIYDLFTKDKSTNL
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: L259_DROME
Sequence: MDKQPVLEPTFDSVSERENTSIEESSLLENNGFDHRNKDESLSVNTSPPLVCRKCFELGHQTENCKQKLTVNSENNSAQNEKEKVLPENPRARSNFISSLCFWYTIPIFRKGYRKTLDSTDLYRPLEEQKSDILGNRLCASWERELKNDGRSPSLVRALLRVFGWQLGFPGLAIFVVELGLRTLQPIFLVKLISYFSGEPDAANAGFYYAVAQIVISALTVMILTPTTFGIHHVCFKMRVAMGSMIFRKALRLTKGALGDTTSGHVVNLISNDIPRLDSAPYTVHYLWVGPLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRTSAIQLKAAERTDNRIRMVNEIISAIQVLKMYAWEQPFEQMVTHAREKEMNTIRQGQYIRGFDFARRIVLSRVAIFLSLVGYVILGKVFTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRRVEQFMQSEELGSSDKSEGPSKDTVPGNPPSNNNEADLLKSAISIRDLKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNGSLSYTSQESWLFSGTVRQNILFGQPMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGDYESLLKTGLITGLGSLSKTDKAKTEEQEPLNLNSPDNKNEVTPIKENSEQTVGGSSSGKEHVERQESGGISLALYRKYFQAGGGLVAFLVMLSSSVLAQVAVTGGDYFLTYWVKKESTAAGHGEMEDMESKSMDVYKYTLIIILSVIMNLSSSFLLFNIAKKASIRLHNTIFNRVTRADMHFFSINKHGSILNRFTKDMSQVDEVLPVVLVDVMQIALWLAGIIIVIANVNPLLLVPTLMLSVIFYHLRNLYLKTSRDLKRVEAINRSPVYSHLAASLNGLTTIRALDAQRVLEKEFDSYQDAHSSAFFMYISTSQAFGYCMNCICVIYISIITLSFFAFPPGNGADVGLVITQAMGLIDMVQWGVRQTAELENTMTAVERVVEYESIEPEGMLEAPDDKKPPKTWPEQGEIIFKELNLRYTPNAKAENVLKSLSFVIQPREKVGIVGRTGAGKSSLINALFRLSYTDGSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTMRYNLDPFDEYSDEKLWGCLEEVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQATIRSKFRDCTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYELMTKSDSKVFHNLVNQSGRASYEGLLKIAQETFESS
What is the function of this protein?
Vital for development.
What are the official names of this protein?
Probable multidrug resistance-associated protein lethal(2)03659, Wunen region A protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TTDT_ECOL5
Sequence: MKPSTEWWRYLAPLAVIAIIALIPVPAGLESHTWLYFAVFTGVIVGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSVIWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSARGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLLIGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETELQAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSNKAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTIVMVALIVVFYLLRYFFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYGSGYLPTVDYWRLGAIFGLIFLVLLVITGLLWMPVVLL
What is the function of this protein?
Catalyzes the uptake of tartrate in exchange for intracellular succinate.  Essential for anaerobic L-tartrate fermentation (By similarity).
What are the official names of this protein?
L-tartrate/succinate antiporter, Tartrate carrier, Tartrate transporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CBIM_SORC5
Sequence: MHLAEGVLPLGWCAFWNALALPFVAIALHLLRRRTEQDAFYKPFVGLIAAAVFAISCMPVPVPTAGTCSHPCGTGLAAVLIGPWMTVLVTVVALLIQALFLAHGGLTTLGADVASMGIAGAFTGYFAFHLARRSGANLWVAGFLAGVTSDWATYATTALALALGLSGEGSVTSMFTGVALAFVPTQLPLGLLEGVMTAGALAFLRARRPDILDRLQVVRLAPGAS
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPP_ACET2
Sequence: MNNVFVMDHPLIQHKISLLRDKNTQTKEFRELVSEISMLMGYEVTRNMPLKEVEIETPVGVARTKVISGKKMGIVPILRAGLGMVDGMLKLLPMAKVGHIGLYRDPETLQPVEYYCKLPCDIAEREIVVLDPMLATGGSASAAIKYLKERGVTSIKLMCLIASLDGIKKINDEHPDVLIYCAAVDDKLNEHGYIIPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: GSH1_ECO81
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: PAG15_BOVIN
Sequence: MGCLCLYRSTLLTGGLLFLLMLADPAFPAGSRPPVVLVPGDMGNQLEAKLDKPSVVHYVCSKRTDHYFTLWLNLELLLPVIIDCWIDNVRLIYNQTSHTTQFPEGVDVRVPGFGDTFSMEFLDPSKSSVGSYLHTMVESLVSWGYERGKDVRGAPYDWRRAPNENGPYFLALRKMIEEMYQLYGGPVVLVAHSMGNMYMLYFLQHQPQDWKDKYIRAFVALGPPWGGVPKTLRVLASGDNNRIPVIRSLKIRAQQRSAVSTTWLLPYSYTWSPQKVFVRTPKANYTLQDYRQFFQDIGFKDGWSMRQDTEGLVEATVPPGVRLHCLYGTGVPTPESFDYESFPDRDPKIHYGTGDGTVNLQSALHCHTWRGLQKQEVSLQALPGNEHIAMLANTTTLAYLKRVLLGP
What is the function of this protein?
Has dual calcium-independent phospholipase and O-acyltransferase activities with a potential role in glycerophospholipid homeostasis and remodeling of acyl groups of lipophilic alcohols present in acidic cellular compartments (PubMed:11790796, PubMed:9525960).  Catalyzes hydrolysis of the ester bond of the fatty acyl group attached at sn-1 or sn-2 position of phospholipids (phospholipase A1 or A2 activity) and transfer it to the hydroxyl group at the first carbon of lipophilic alcohols (O-acyltransferase activity) (PubMed:11790796, PubMed:9525960).  Among preferred fatty acyl donors are phosphatidylcholines, phosphatidylethanolamines, phosphatidylglycerols and phosphatidylserines (By similarity).  Favors sn-2 over sn-1 deacylation of unsaturated fatty acyl groups of phosphatidylcholines and phosphatidylethanolamines (By similarity).  Among preferred fatty acyl acceptors are natural lipophilic alcohols including short-chain ceramide N-acetyl-sphingosine (C2 ceramide), alkylacylglycerols, monoacylglycerols, and acylethanolamides such as anandamide and oleoylethanolamide (By similarity).  Selectively hydrolyzes the sn-1 fatty acyl group of truncated oxidized phospholipids and may play a role in detoxification of reactive oxidized phospholipids during oxidative stress.  Required for normal phospholipid degradation in alveolar macrophages with potential implications in pulmonary surfactant clearance (By similarity).  At neutral pH, hydrolyzes the sn-1 fatty acyl group of the lysophosphatidylcholines (By similarity).
What are the official names of this protein?
Phospholipase A2 group XV, 1-O-acylceramide synthase, ACS, LCAT-like lysophospholipase, LLPL, Lysophospholipase 3, Lysosomal phospholipase A and acyltransferase, Lysosomal phospholipase A2, LPLA2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Lysosome. Secreted. Membrane; Peripheral membrane protein.