PharMolix/UniProtQA huggingface dataset:
Protein: EIF3K_DROGR
Sequence: MSHLVKMENGQSQTIQEMLGCIERYNPDHLKILESYVQDQAKNNSYDLEANLAVLKLYQFNPHMLNFDITYTILLKSLTNLPHTDFVMAKCLLLPQQMKDENVQTIIDLADILERADFTLFWQRAEVNRTMFRHIAGFHDSIRKFVSHVVGTTFQTIKKDLLKELLGGIEDSTLESWIKRNGWKHQGHDLVVVATQDDKIKTKNITEKIEFENVGALMAQCL
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACC_STRPZ
Sequence: MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSRVLNDFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEILEKGPLLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIGIANLNGKKTVLDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFDALKEVLQDKLFDGIEWIIVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKIKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: DJB11_HUMAN
Sequence: MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHPIFERRGDDLYTNVTISLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY
What is the function of this protein?
As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins (PubMed:10827079, PubMed:15525676, PubMed:29706351).  Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed (PubMed:15525676).  May help recruiting HSPA5 and other chaperones to the substrate.  Stimulates HSPA5 ATPase activity (PubMed:10827079).  It is necessary for maturation and correct trafficking of PKD1 (PubMed:29706351).
What are the official names of this protein?
DnaJ homolog subfamily B member 11, APOBEC1-binding protein 2, ABBP-2, DnaJ protein homolog 9, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, Endoplasmic reticulum DNA J domain-containing protein 3, ER-resident protein ERdj3, ERdj3, ERj3p, HEDJ, Human DnaJ protein 9, hDj-9, PWP1-interacting protein 4.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=Associated with the ER membrane in a C-terminally epitope-tagged construct.
Protein: GUAA_PARD8
Sequence: MHEKLIILDFGSQTTQLIGRRVRELNMYCEIVPYNKFPHDATDVKGVILSGSPYSVYDENAFKADLTEIRGKYPVLGICYGAQFLAYTSGGNVEPANSREYGRANLSHIDGEDELLKGIHVGSQIWMSHGDTITVLPDNFKVIASTDDVRAAAYHVEGEQTWGVQFHPEVFHSTDGTKLLDNFLNICGCAKDWTPASFIESTVAELKEQLGDDKVILALSGGVDSSVTAVLLNKAIGKNLTCIFVDHGLLRKNEFENVMRDYEHLGLNVIGVNAKDKFYKELAGVTEPEKKRKIIGKGFIDVFDEEAHKLKDIKWLGQGTIYPDVIESLSITGTVIKSHHNVGGLPDTMNLKLVEPLRLLFKDEVRRVGMELGMQPHLIKRHPFPGPGLGIRILGDITPEKVRILQDADDIYMSLMREWGLYDKIWQAGVILLPIQSVGVMGDERTYENTVALRAVTSTDAMTADWAQLPYEFLAKVSNEIINKVKGVNRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DADD_METTH
Sequence: MDNESILITGPEILDAGGIRRGSVLIEDNRIADVSNTLSPGDADTVIDGTGKLLIPGLVNTHTHLSMTLFRGIADDLPLDRWLNDHIWPAEARLNGDYCYAGALLGCIEMIRSGTTSFNDMYFYMDHVARAVEEAGLRCVISHGMIDLGDTEKMTAELRESRRIIKECHGMADDRIRVALGPHSPYTCSEELLKETAALADKNDLMIHIHVSETENEVSEVSRSHGMTPVEYLDEVGVLGPRTVAAHCVWLKDWEIDVLAERDVKVSHNPSSNMKLASGVSPVARLLQRGVNVSLGTDGAASNNNLDMFQEMKTASLLQKVNLEDPTALPAMDVFSMATLNGARALGIDAGLIAPGKLADIVILNTRRPHLTPWRNPPSHTVYSASGADVDTVICDGRILLRDGELEVLEEKYVMELAEAAAAELTG
What is the function of this protein?
Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs.  Can also deaminate adenosine.  The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
What are the official names of this protein?
5'-deoxyadenosine deaminase, 5'-dA deaminase, 5'-methylthioadenosine deaminase, MTA deaminase, Adenosine deaminase, S-adenosylhomocysteine deaminase, SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: TBB_HORVU
Sequence: MREILHIQGGQCGNQIGAKFWEVVCDEHGIDPTGRYTGTSDLQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDSVRTGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPTGLSMASTFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEGEYEDEDQEAEDDM
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RF2_NEIG2
Sequence: MEAEVINQLNNTLNDLEKRSEDIRVYMDYQGKKDRLEEVIGLSEDPELWNDPKRAQEIGKESKILEGIVLTLDNIASGIEDNRMLIEMAVEENDEEGFAAVKEDVAGLEKQMADLEFKRMFNQPADPNNCFIDITAGAGGTEAEDWAGMLFRMYSRYAERKGFKIEILEEDDGEIAGINRATIRVEGEYAYGLLRTETGVHRLVRYSPFDSNNKRHTSFASVFVYPEIDDSIEIEINPADLRIDTYRASGAGGQHINKTDSAVRITHEPTGIVVQCQNDRSQHANKAAAMEMLKSKLYELEMRKRNEEKQALEEGKSDVGWGSQIRSYVLDSSRIKDLRTGYEVGNTKAVLDGDLDGFIEASLKQGV
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUS_NPVBM
Sequence: LETVIVDNIKCNNKNCIIICNKKNCIVFNCIFNYKIS
What is the function of this protein?
Envelope phosphoglycoprotein which mediates the fusion of viral and host endosomal membranes leading to virus entry into the host cell.
What are the official names of this protein?
Major envelope glycoprotein, gp64.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae gp64 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: SYP_SYNJB
Sequence: MQQSQRLSQMLFVTLREDPVEAELPSHKLLLRGCFIRRLSPGIYTYLPLLWRVLQKISEIVRQEMNAIGGQECLLPQLQPAEIWRESGRWDVYTQAEGIMFALKDRQGREQSLGPTHEEVITLLARDLIRSYRQLPQTLYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHANEESLRQTYQDMYRAYSRILRRCGLEFRVVDADAGAIGGPSAASQEFMVLASAGEDEILYTPDGSYAANVEKAVSIPPPAAESPYTAFQVLDTPGTETIEKLAAFLKISSTLIVKNVLYQALYDNGLRVAVLLSIRGDQEVNEVKLANHLSRLAERYQASKLLKLALADAEIQNSWQGDPIPVGYIAPDLPDSCLGRQKNLAPQILRLADQTAALLQNFVTGGNQVGQHVVGANWGEQYPLPEVVDVRKAQAGDRCLLNPDQILETARGIEIGHIFQLGLKFSLPMRATFTDEQGSEQPLWMGCYGIGVSRLAQAAVEQSHDANGIIWPVAIAPYHVVVVVPNISDPEQMSVAEKLVQDLATAGIETLWDDRDERAGVKFKDADLIGIPYRITTGRSLKQGKVELTERASGQATEIPIEEVVTTLKERIEAALAVPD
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT21B_ARATH
Sequence: MIISKQLFLLFFLLFFIFPLRHASNPSKCSSSNSRPHRCGPLEVPIRFPFCDHPLFNLLCTNLNNTVLQLPMSGTFFVQYIDYRKQQIYINDPENCLAKRLLTFNISGSPFSPRFDTLYTFLTCPNELVLPSWYPSIPCLSNSTSSFFATSNFALAESMLPSCQIVKRIYVPADSPFAETRFSSYLNQSLLLEWNSPNCRGCEIDYLRCGFKNKASPEVKCFGAKKSGHLSRAVVAVLICLSIIGAVILFVTCIAIRIHNTPRRRHWAVPAAAATVMQQPREVMATRGLDQSTIEKYKTMELGESRRPPGTNGIVCPICLSEYVSKETVRFIPECDHCFHAKCIDVWLKIHGSCPLCRNSRA
What are the official names of this protein?
Putative RING-H2 finger protein ATL21B, RING-type E3 ubiquitin transferase ATL21B.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: METJ_VIBVY
Sequence: MADWNGEYISPYAEHGKKSEQVKKITVSIPLKVLKVLTDERTRRQINNLRHATNSELLCEAFLHAYTGQPLPTDEDLRKDRPDDIPTEAKELMTAMGIEFEAYDD
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFT43_CAEEL
Sequence: MIILENEANEPGFRIQQRAESETGKKGRFGGILKENPIKGFSSETLTRPLTGLFRKTGKSQRKTDDDDSQETIAAPPTNFPNMARISATIESVQINDEYAGYRDRNPETGSKLTLNEGAGVFGNAMHPLTRYFKVGDVDVSILGRSFPTEKTVDEEGPWTAQSLFNSLESRIKKERIDAKDQPSDSRSRNARETLISSKY
What is the function of this protein?
As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis (Probable).  In particular, may act redundantly with the intraflagellar transport protein ift-139 to regulate the transport of specific ciliary cargo proteins such as che-3 which are related to motility.
What are the official names of this protein?
Intraflagellar transport protein 43 homolog.
What is the protein family that this protein belongs to?
Belongs to the IFT43 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: BCHB_HELMO
Sequence: MKLAYWMYEGTALSGITRVAGSMQKVHTVIHGPQGDGYVNVMYSMLERFHTIPPFTLSTIGRREMAQGSRARLVETVRRVDAQHQPDVIVITPTCSSTLLQEDLLAVARTLGKQTKAKLIVPNVNAFRDLEHRAMDDFLTQIVAEFATEQPKTEQFSVNLIGPSYLGFHQLHDMQEIRSMLESLGVAVNAVIPYGASIKTLQELTKAHLNICLYHEYGQSACELLKEKFGIDYIVATPIGIRLTSQFVKAIGERAGLPVESYIRQNLAPSGTIARFTKSVDSLSALFGKRAVVFGDYSHAVGMTHLLREIGVRVVWAGTYMKTMEKAFQASIGGLADEVFVCDDFQEISHKIRDTHPDIVLGTQMERHSAARFNFPCIVISSPAHILNFPLFPAPVLGYQGMTRMLDTINSTIKLGLEEHLVNMFGEDSPGMGEEDTAQEQVAVTSDMPKAPDKTTAGEGELKWDAEATKALKQVPFFVRGKVQRNTENYARERGYSEVTLEVIYAAKAYFESKSNQGER
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: QCR6_RAT
Sequence: MGLEDERKMLTGSGDPKEEEEEELVDPLTTVREHCEQLEKCVKARERLESCDRRVSSRSQTEEDCTEELFDFLHARDHCVAHKLFKSLK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 6, mitochondrial, Complex III subunit 6, Complex III subunit VIII, Cytochrome c1 non-heme 11 kDa protein, Mitochondrial hinge protein, Ubiquinol-cytochrome c reductase complex 11 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCRH/QCR6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: PRIB_SALAR
Sequence: MTNRLALSGTVCRAPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).  During primosome assembly it facilitates the complex formation between PriA and DnaT.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: PFLB_HAEIN
Sequence: MSELNEMQKLAWAGFAGGDWQENVNVRDFIQKNYTPYEGDDSFLAGPTEATTKLWESVMEGIKIENRTHAPLDFDEHTPSTIISHAPGYINKDLEKIVGLQTDEPLKRAIMPFGGIKMVEGSCKVYGRELDPKVKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGVDFLMKDKYAQFSSLQKDLEDGVNLEATIRLREEIAEQHRALGQLKQMAASYGYDISNPATNAQEAIQWMYFAYLAAIKSQNGAAMSFGRTATFIDVYIERDLKAGKITETEAQELVDHLVMKLRMVRFLRTPEYDQLFSGDPMWATETIAGMGLDGRTLVTKNTFRILHTLYNMGTSPEPNLTILWSEQLPENFKRFCAKVSIDTSSVQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTLLYAINGGIDEKLGMQVGPKTAPITDEVLDFDTVMTRMDSFMDWLAKQYVTALNVIHYMHDKYSYEAALMALHDRDVYRTMACGIAGLSVAADSLSAIKYAKVKPVRGDIKDKDGNVVATNVAIDFEIEGEYPQYGNNDNRVDDIACDLVERFMKKIQKLKTYRNAVPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDAEAQRRNLAGLMDGYFHHEATVEGGQHLNVNVLNREMLLDAMENPDKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTESM
What is the function of this protein?
Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
What are the official names of this protein?
Formate acetyltransferase, Pyruvate formate-lyase.
What is the protein family that this protein belongs to?
Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_BURA4
Sequence: MTQWEVVIGLETHAQLSTVSKIFSGAPTQFGAEPNTQACPVDLALPGVLPVLNRGAVERAIRFGLAIGSTIAPRSIFARKNYFYPDLPKGYQISQYEIPVVQGGQITIQVPANEKAGKPAYEKTVNLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPEMRSAAEAVAYAKSLHALVVWLGICDGNMQEGSFRCDANVSVRPVGQEKFGTRAEIKNLNSFRFLEEAINYEVRRQIELIEDGGEVVQETRLYDPDKRETRSMRSKEDAHDYRYFPDPDLMPLVIGQDWIERVQAGMPELPAAMQQRFVEQYGVSAYDAGVLTSSKAMAAYFEAVVAKAGAANAKIAANWLMGDVSSQLNRDGIEIDAIPVSAAQLALVLQRIADGTISNKIAKEIFSAIWDEKATDEAAADRIIDAKGLKQISDTGALEAIIDEVLAANAKSVEEFRAGKEKAFNALIGQAMKATKGKANPQQVNELLKKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: DNAA_NOCFA
Sequence: MDDEQNVLATVWPEVIAELTTGSADGSIPAVTRAQQAWLKLVKPITVAQGFALLSVPSSLAQEAIERDLREPILRSLGRRLGPQVEGLGVRIAAPATPTAERAAANPRHARMTSRPERPRGERPVPGLPGQEAVDRPETLPRYSQAAESVPGYPARQDHSRPGDYPPAAEYTPAAEYTPAAEYTPAAEYSPEPEYTPATDYPGADDYPTTVFRLPPGGFAEPPGDGRPGGVPEISTPRRDGHGPRRDATPPGQEALFTPEPGDRPLRDTDRPLREPAAGHDVRESDGPVERDDEPVVNIRDSWPTYFAKNQESTPAPANSSASLNAKYTFETFVIGASNRFAHAAAVAIAEAPARAYNPLFVWGASGLGKTHLLHAAGHYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRRYRETDILLVDDIQFIEGKEGIQEEFFHTFNTLHNANKQIVVSSDRPPKQLATLEERLRTRFEWGLITDVQPPELETRIAILRKKARMDRLDVPHDVLELIASRVERNIRELEGALIRVTAFASLNGQPLDLSLAEVVLRDLMPDTATLEINAATIMAVTAEYFNTTLEELTGPGKARPLAQARQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAEKKVRKEMTERRRVYDQVQELTARIKQRSR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_BLOPB
Sequence: MIHDYHITHFLISVPAVYCLPNEKIGMEVAFVGYSNSGKSSAINALTYQKKLTKVSKTPGCTQLINLFEVSPGIRLIDFPGYGYAKKTKKRKNYWHDVICEYLKKRKNLKGLILMMDIRHPIKDLDQKTIESALSVDVPVFTLLSKSDKISRNILQVTSKKIIHDMKMMFETHIQVEPFSVVKKYGIHSLKRVLNNWLR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: GATA_PROM1
Sequence: MTFEDLRQKLKSGEVSSKELVQEKINRINELDPTLNSFLIVNTELALSKAEHIDKQIASGDHLPPLSGIPIAIKDNLCTKGIKTTCASKILDNFVPPYESTVTKKLLNAGAIMIGKTNMDEFAMGSSTETSAFGPTLNPWNITKVPGGSSGGSAASVAAGLCYGSLGSDTGGSIRQPASFCGVVGMKPTYGRVSRWGLIAFASSLDQVGPFANNVSDAAEILQVISGKDELDSTTVDIPVPNYLETLSKSIKGMKIGLIDNCFDHEGLATDVKESVLSSASLLENLGAEIVNISCPRFNDGIATYYVIAPSEASANLARYDGVKYGFRAEDEQSLIEMTSKSRALGFGSEVKRRILIGTYALSAGYVDAYYKKAQQVRTLIRRDFDDAFKKVDVLLAPTAPTTAFGSGDNIDNPMAMYLSDLLTIPANLAGLPAISLPCGFDKSDLPIGLQLIGNVFEEGKLLQVANQFEKAAEVYKNRPKTDFTL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MOAC_SHEPW
Sequence: MTNAFTHINADGNAHMVDVTDKSVTEREARAEAYIEMASDTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLMLTKVEVELEAQPEHNRVWIRSLCKLSGKTGVEMEALTAASTAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ORTH4_ARATH
Sequence: MAIQTQLPCDGDGVCMRCQVTPPSEETLTCGTCVTPWHVSCLLPESLASSTGDWECPDCSGVVVPSAAPGTGISGPESSGSVLVAAIRAIQADVTLTEAEKAKKRQRLMSGGGDDGVDDEEKKKLEIFCSICIQLPERPVTTPCGHNFCLKCFEKWAVGQGKLTCMICRSKIPRHVAKNPRINLALVSAIRLANVTKCSGEATAAKVHHIIRNQDRPDKAFTTERAVKTGKANAASGKFFVTIPRDHFGPIPAANDVTRNQGVLVGESWEDRQECRQWGVHFPHVAGIAGQAAVGAQSVALSGGYDDDEDHGEWFLYTGSGGRDLSGNKRVNKIQSSDQAFKNMNEALRLSCKMGYPVRVVRSWKEKRSAYAPAEGVRYDGVYRIEKCWSNVGVQGLHKMCRYLFVRCDNEPAPWTSDEHGDRPRPLPDVPELENATDLFVRKESPSWGFDEAEGRWKWMKSPPVSRMALDTEERKKNKRAKKGNNAMKARLLKEFSCQICRKVLSLPVTTPCAHNFCKACLEAKFAGITQLRDRSNGVRKLRAKKNIMTCPCCTTDLSEFLQNPQVNREMMEIIENFKKSEEEAEVAESSNISEEEEEESEPPTKKIKMDNNSVGDTSLSA
What is the function of this protein?
E3 ubiquitin-protein ligase.  May participate in CpG methylation-dependent transcriptional regulation (By similarity).
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase ORTHRUS 4, Protein VARIANT IN METHYLATION 4, RING-type E3 ubiquitin transferase ORTHRUS 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: NTCA_SYNY3
Sequence: MDQSLTQDRPLAAVFRRLGSELMPPVVETFDRSKTIFFPGDPAERVYFLLKGAVKLSRVYEAGEEITVALLRENSVFGVLSLVTGQRSDRFYHAVAFTPVELLSAPIEQVEQALKEHPDLSLLMLQGLSSRILQTEMMIETLAHRDMGSRLVSFLLILCRDFGVPAPDGIRIDLKLSHQAIAEAIGSTRVTVTRLLGDLREGNMISITKKKITVHNPVALSQQFT
What is the function of this protein?
Required for full expression of proteins subject to ammonium repression.  Transcriptional activator of genes subject to nitrogen control.
What are the official names of this protein?
Global nitrogen regulator.
Protein: RL16_BRUSU
Sequence: MMQPKRTKFRKQFKGRIHGNSKGGTDLNFGAFGLKALEPERVTARQIEAARRAITRHMKRAGRVWIRIFPDLPVTSKPTEVRMGKGKGSVDYWACRVAPGRVMFELDGVPEDVAREALRLGAAKLPIKTRFIQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.