PharMolix/UniProtQA huggingface dataset:
Protein: RL21_VIBHA
Sequence: MYAVFQSGGKQHRVSEGQTLRLEKLDVETGATVEFDKVLLVANGEDIKVGAPLVEGGKVVAEVVQHGRGDKVKIVKFRRRKHSRKQQGHRQWFTEVKITGINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NNRE_ROSLO
Sequence: MPDILTASQMRALETAAFNSGAVTGLELMERAGQSVIDALFSSKAELATGEHRAVILCGPGNNGGDGFVIARLLFVLGWQVRVYLYADPEKMPRDAHANHDSWVDLVPECTQRISFPSVLPAEAERFGDEAFGNGEVDVIVDALFGIGLNRPLSGLHPILATCHANRHEAYFVAVDVPSGLGENGPLEAADWSVFPADLTVTFHRPKQAHQNGLSFCGKIMVQYIGL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: MET_LOXAF
Sequence: MKAPAVLAPGVLVLLFTLVRKSHGECEEALAKSKMNVNMKYQLPNFTADTPIQNVVLHEHHIFLGAINNIYVLNDKDLQKVAEYKTGPVLEHPDCLPCQDCSSKANLSGSVWKDNINMALLVDTYYDDQLITCGSVNRGTCQRHVLPPDNPADIHSKVHCMYSPQADEEPSKCPDCVVSALGTKVLLTEKDRFINFFVGNTVNSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYVHAFKHNQFIYFLTVQRETLESQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSAREEVFNILQAAYVSKPGAYLAKQIGALPDDDILYGVFAQSKLDSAEPMNRSAVCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRRDEYRTEFTTALQRVDLFTGQFNQVLLTSISTFIKGNLTIANLGTSEGRFMQVVVSRSGLTTPHVNFRLDSHAVSPEVILEHPLNQNGYTLVITGKKITKIPLDGLGCDHFQSCSQCLSAPSFVQCGWCHNKCARAEECPNGMWTQEICLPTIYEVFPTSAPLEGGTTLTVCGWDFGFRRNNKFDLKKTRVLIGNDSCTLTLSESTTNTLKCTVGPAMNKHFNLSIIISNGRGTARYRTFSYVEPVITSISPSYGPKAGGTLVTLTGKYLNSGNSRHISIGGKTCTLKSVSDSVLECYTPAQSISTDFPVKLKIDLANREAYSFSYQEDPTVYEIHPNKSFISGGSTITGIGKNLNSVSVPRMVINVQEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSNYFDLIYVHNPVFKPFKKPVMISMGNENVLEIKGDYIDPEAVKGEVLKVGNKSCENIHLQSEAVLCTVPNDLLKLNSELNIEWKQAVSSTVLGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTNGDSDSSIPLLQNNVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNGDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNTTYVNVKCVAPYPSLLSSQDSVDDEVDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CLSA_SALEP
Sequence: MTTFYTVVSWLVILGYWVLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAQENSSVASSLFKLCERRQGIAGVKGNQLQLLTDSDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWAAMMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMVMIDNYIAYTGSMNMVDPRFFKQDAGVGQWVDLMARMEGPVATAMGIVYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTATYAAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSLLVGWASRAFFSELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLVIDDTGFGADLAAVQDDYISRSRLLDARLWVKRPLWQRITERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIRC5_HUMAN
Sequence: MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD
What is the function of this protein?
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (PubMed:9859993, PubMed:21364656, PubMed:20627126, PubMed:25778398, PubMed:28218735).  Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (PubMed:16322459).  Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules (PubMed:20826784).  Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis (PubMed:20929775).  The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (PubMed:18591255).  May counteract a default induction of apoptosis in G2/M phase (PubMed:9859993).  The acetylated form represses STAT3 transactivation of target gene promoters (PubMed:20826784).  May play a role in neoplasia (PubMed:10626797).  Inhibitor of CASP3 and CASP7 (PubMed:21536684).  Essential for the maintenance of mitochondrial integrity and function (PubMed:25778398).  Isoform 2 and isoform 3 do not appear to play vital roles in mitosis (PubMed:12773388, PubMed:16291752).  Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform (PubMed:10626797).
What are the official names of this protein?
Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin.
What is the protein family that this protein belongs to?
Belongs to the IAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Midbody. Note=Localizes at the centromeres from prophase to metaphase, at the spindle midzone during anaphase and a the midbody during telophase and cytokinesis. Accumulates in the nucleus upon treatment with leptomycin B (LMB), a XPO1/CRM1 nuclear export inhibitor (By similarity). Localizes on chromosome arms and inner centromeres from prophase through metaphase. Localizes to kinetochores in metaphase, distributes to the midzone microtubules in anaphase and at telophase, localizes exclusively to the midbody (PubMed:11084331). Colocalizes with AURKB at mitotic chromosomes (PubMed:14610074). Acetylation at Lys-129 directs its localization to the nucleus by enhancing homodimerization and thereby inhibiting XPO1/CRM1-mediated nuclear export (PubMed:20826784).
Protein: P2A07_ARATH
Sequence: MSEVAVVLEKQEGGGGGGPSSIQCPMLKSTNYTVWDMRMRSTLKVHKSQEEDVSKGLINFLEPVLQNKNINVFIDEEEVRGKGLKNLFKRIQDSKISLAIFSESKCDFNDLLKNNESADEAIPIFYKVDATGDLADLQNSVKCKKDLINSAVEEMSKLLANISVGVYREKEANSKCFMVPARKLQMSHSEKLINWTWSSIYETPNDAAIEVAMLNEVHWLHMSGNFHTRNLTPGTKYEVVFLVSLDDTSSGWEQPVNLNLKVINPDGTESLQERETSLECHIGENWVDIQAGVLVAPPRNAAAKMTFTMYQYVTSDRKSGLVVKGVAIRPMQ
What are the official names of this protein?
Uncharacterized protein PHLOEM PROTEIN 2-LIKE A7, AtPP2-A7.
Protein: AP1_CANGA
Sequence: MAEVDNGGAQKSSASRKKRYQELDPETRMKRVAQNRAAQKAFRERKERKMKELERKVVDLENLTKLNEVETNFLRDQLSILVKELRKYRPETKQDHKVLKYLEKHKGGAAGAGNGAATGSVSTSTRHTDLAASNANRVSKDSSILPGAKIIRQDLESFNENRHFNVTGQLTPPGNTSSSTTANSVAANAKKQSIPHSDSSDSNESKNTWNTDPTSSEDWLDDVMTSHKQISRGQSGSGIDFNNFFDEQVSEFCTKLNQACGTKACPIPQSKSAATTPLPGTSSNGNSNSPMIINDTMGDVSLNMQGNEHGNATNNLVTDPAFLSNTWDDMSPASNQHSTGGAPGFGQLGFGDNLLGNDILFSPNSPAYSPSVLGSGRTQEVYRSPAVQKVVEKENESKSVNFPFINSSLAFPGDYDNNFFRETTDLNFDDNDQDDNFTNSNDLVNDYFTTNIPDTDNSDSALIANGLVKEEPSMQTEDTFKVQNTNDMLNSSRMKETIDNQNIGEKTTKDDNEDDDEDDENDNTVVPSRDDGLLRCSEIWDRITAHPKYSDIDIDGLCSELMAKAKCSERGVVINADDVQVALNKHMS
What is the function of this protein?
Transcription factor that plays a critical role in response to various stresses and reduces the stress through transcriptional activation of its target genes including multidrug transporter FLR1 (PubMed:17046176).
What are the official names of this protein?
bZip transcription factor GAP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTHY_ECO55
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: Y3044_PYRAE
Sequence: MSEGSFEDRELEEIRRKKLEELQKKAELERQAQIVAAQRRIALKKILTPEALARLDNIRVVRPELAEALEQQLINLAATGRVRVPIDEETLKKILEAVYSQTRREYRFRL
What are the official names of this protein?
DNA-binding protein PAE3044.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: SODC_EMENI
Sequence: MVKAVAVLRGDSKVSGTVTFEQADENSNTTVSWNITGNDPNAERGFHIHQFGDNTNGCTSAGPHFNPFGKTHGAPEDEVRHVGDLGNFKTDAEGNSKGSKTDKLIKLIGAESVLGRTLVVHAGTDDLGRGDSEESKKTGNAGARPACGVIGIAA
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP2BC_MOUSE
Sequence: MSVRRPQFSTTERVIKAVPFPPTRRLTLKEVFENGKPKMDLLKNHLVKEGRVEEEVALKIINDGAAILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYDACMHTFDCLPLAALLNQQFLCVHGGMSPEITCLEDIRKLDRFSEPPAFGPVCDLLWSDPLEDYGSEKTLEHYTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDEEMNVTDEEGATTGRKEVIKNKIRAIGKMARVFTVLREESENVLTLKGLTPTGTLPLGVLSGGKQTIETAKQEAAEEREAIRGFTIAHRIRSFEEARGLDRINERMPPRKEASYHHDAGRMHSHSHPPHPQASRRTDHGKKAL
What is the function of this protein?
Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals.  Dephosphorylates and activates transcription factor NFATC1.  Dephosphorylates and inactivates transcription factor ELK1.  Dephosphorylates DARPP32.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, CAM-PRP catalytic subunit, Calcineurin, testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2B subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Note=Localizes in the mitochondria in a SPATA33-dependent manner.
Protein: HIS4_THEFY
Sequence: MAPILELLPAVDVAGGQAVQLVQGKDGTGGRYGDPLNAALTWQNAGAEWIHLVDLDAAFGRGHNRELLASIVGKLDIKVELSGGIRDDESLNAALATGCHRVNIGTAALENPDWCAKVIAEHGDRVAIGLDVRGTTLAARGWTRDGGDLYETLERLEAAGCARYIVTDVNKDGTLKGPNLDLLRDVCSRTDKPVVASGGISSLDDLRALAALVPEGVEGAIMGTALYEGAFTLEEALATVREVAQ
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCKG_PYRHO
Sequence: MRVVFKLPDELRQELKNPLGELIEGNIPEPYVKAKNIIEGDDGVLITVGDVVTENIMRVGLNPNLAIYDHKTERREYKPRIIINGVLLTVKNPPGTITLPLLKSIKKAYSLILNGKSVHIVVNGEEDLATIPAVLYAPLGATVIYGQPKRGIVLIKVTNECKRRCAKIMRRMEVVRDGD
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: YDGC_ECO57
Sequence: MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHYIVASERGIEALRATIIFSMWSIIPYFVYLVSLWYFTGMMRLPAAFVGSVACWGISAWVLIICWIKLH
What are the official names of this protein?
Inner membrane protein YdgC.
What is the protein family that this protein belongs to?
To P.aeruginosa GlpM.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHF5A_ARATH
Sequence: MAKHHPDLIMCRKQPGIAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSFQGRCVICGGVGISDAYYCKECTQQEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR
What are the official names of this protein?
PHD finger-like domain-containing protein 5A.
What is the protein family that this protein belongs to?
Belongs to the PHF5 family.
Protein: THIC_BART1
Sequence: MSKNIPLISCSPFPASRKIYQQSPLFSDVRVPLREISLTDGSGEKPLNVYDTSGPYTDKEAIIDLTKGLPAIGSSWLSKRADTEPYPARSVKPEDNGLTSSPIPAFEKKRPILRAKSGKAITQMAYARAGIITAEMEYVAIRENEGLAIKDQQTVQSSPLGGEIPEIYTAEFVRNEIANGRAIIPQNINHPECEPMIIGRNFRVKINANIGNSAVTSSMAEEVDKMVWAIRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVQGIAENLTWDIFRDTLIEQAEQGVDYFTIHAGLRLPFIPMTIDRITGIVSRGGSIMAKWCLHHHKESFLYENFDEICDIASTYDISLSLGDGLRPGSIADANDEAQFAELKTLGELTKTAWEKNVQVMIEGPGHVPMHKIKENMEQQLDLCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDKNDVKTGVITYKIAAHAADLAKGLPRAQLRDNALSRARFDFRWHDQFNLSLDPETACAFHDETMPKDAHKLVHFCSMCGPKFCSMRISHDIRDAAALKKAKGEGMVAMAEKYQERGDIYVEAPQKKRVNS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: UMP1_SCHPO
Sequence: MKIVPDVEPAAEVSGNFKVSVLEPSIPAVHRVENKHPLESRLKNWEAQQQQIRLDSMRRIYGLHEPVRREMEQKLASQSSRPLALGGSANFHLDILANREAVLDETDIYAAPIPLEMTYQNEMAIRYGL
What is the function of this protein?
Short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex.  Required for the correct assembly and enzymatic activation of the proteasome (By similarity).
What are the official names of this protein?
Probable proteasome maturation factor ump1.
What is the protein family that this protein belongs to?
Belongs to the POMP/UMP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NAR2B_RAT
Sequence: MPSNICKFFLTWWLIQQVTGLTGPLMLDTAPNAFDDQYEGCVNKMEEKAPLLLQEDFNMNAKLKVAWEEAKKRWNNIKPSRSYPKGFNDFHGTALVAYTGSIAVDFNRAVREFKENPGQFHYKAFHYYLTRALQLLSNGDCHSVYRGTKTRFHYTGAGSVRFGQFTSSSLSKKVAQSQEFFSDHGTLFIIKTCLGVYIKEFSFRPDQEEVLIPGYEVYQKVRTQGYNEIFLDSPKRKKSNYNCLYSSAGARESCVSLFLVVLPSLLVQLLCLAEP
What is the function of this protein?
Has both NAD(+) glycohydrolase and ADP-ribosyltransferase activity (to a lesser extent).
What are the official names of this protein?
T-cell ecto-ADP-ribosyltransferase 2, ADP-ribosyltransferase C2 and C3 toxin-like 2, ARTC2, Alloantigen Rt6.2, Mono(ADP-ribosyl)transferase 2B, NAD(+) glycohydrolase, T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 2, T-cell mono(ADP-ribosyl)transferase 2, T-cell surface protein Rt6.2.
What is the protein family that this protein belongs to?
Belongs to the Arg-specific ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: ATPB_RHOP2
Sequence: MATPANQTGRITQVIGAVVDVQFEGHLPAILNAIETKNGDNRLVLEVAQHLGESTVRTIAMDTTEGLVRGQEVTDTGNPIMVPVGVGTLGRIMNVIGEPVDEQGPVANEGLRPIHAEAPTYTDQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIQELINNVAKAHGGYSVFAGVGERTREGNDLYHEFIESGVNKKGGGEGSKCALVYGQMNEPPGARARVALSGLTVAEHFRDQGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTHKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLNRAISEKGIYPAVDPLDSTSRMLSPLIVGEEHYQTARMVQQVLQKYKSLQDIIAILGMDELSEEDKLAVARARKIERFLSQPFFVAEIFTGSPGKFVDLADTIKGFRAICEGKYDHLPEAAFYMVGAIEEAVEKGKKLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MEP5_TRITO
Sequence: MHGLLLAAAGLLSLPLHVIAHPQPSTNLAGRGVDLDAYRMADRSSYMNSDDMKLKQPGIASLSGGNYVDTATEVVKRMVPGMTFRMVDDHYVGESGISHVYFRQTMHGMDIDNSDFNVNIGKDGKVLSFGHSFYTGPAPDKAPVEKRDFSDPMKAFHGACKALNLPINADKATVQTMNEHEVMFMGTSGAMSDPQGKLCYMAKEDGTLALTWRVETDMGDNWLLSYVDAKETEKVHNVVDYVSHATYQVYRWPIPDPTEGKRETIENPWNLKTSPFTWISDGKTNYTTTRGNNAIAQANFDGGEDYLNNHRPNNKNLKFEYPYAPNMSPKSYIDASVTQLFYSANMVHDLYYMLGFTEKAGNFQVNNHGQGGKGNDFVILNAQDGSGTNNANFATPPDGKPGRMRVYIWTKAKPARDSSFEAGTVIHEYTHGLSNRLTGGPANAGCLNGMESGGMGEGWGDFFATAIRLKPNDNRNANYVHGEWVNNSPKGNRMYPYSTSLQTNPLVYTSCNKYNEVHAIGTVWGSMLYEVLWNLIDKHGKNDGPTPVFENGVPKDGKYLAMKLVMDGMAIQPCKPTFVQARDAIIDADMNLTKGSNRCEIWKAFAKR
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 5, Fungalysin MEP5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_STRAW
Sequence: MSESNVTETNEQRGFRKTREGLVVSDKMDKTVVVAVEDRVKHALYGKVIRRTNKLKAHDEQNAAGVGDRVLLMETRPLSATKRWRVVEILEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NFUA_XANOM
Sequence: MIQISDKAQTYFRKLIEREGVPGMGVRLSAVDAGTPRADARLEFAEPADLSGDEWAIDCDGFTLYVVAASVPWMDGAEIDYVTQSTGNQQLTIKAPKIKGEAPAESASMVERVRWVVENEINPQLASHGGRVAVQEVSADGVVLLRFGGGCHGCGMADVTLKQGIEKTLMGRVPGVIAVRDATDHATGDAPYIPRDSAA
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: RBSD_STAHJ
Sequence: MYKTGILNSDISKVLSDLGHTDQIVIADCGLPVPKDVKKIDLALTLGQPSFLEVYEVLKQHMEIEHVTIAEEMEVDNAPIFEQVTKDFSEIEQVNHETFKALTKNAKAIIRTGEATPYANIILQSGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_LEVBA
Sequence: MKILEDRIRQDGTVLTGNVLKVDNFLNHQVDPQLMNELGQEFARRFQDAHITKILTVESSGIAPAVMAGLHLNVPVIFARKHKSLTLTDNLYTAKVYSYTKQVTNEISIDRRFLAADDRVLIIDDFLANGQAVQGLLDIAKTAQITVAGVGVVIEKRFQKGHQMVTDAGIQLEALASIASFEAGQVIFAQD
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_KLEP3
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFDISYDNYHSTHSDENRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIDPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDTTSFDEYWKKDSSAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFISKRFDGVLAAELADPALYKTFTDAAESIGEAWDSREFGKAIREIMALADVANRYVDEQAPWVVAKQEGRDADLQAICTMGLNMFRVLMTWLKPVLPQLAARAEAFLNSELSWDAIQQPLLAHKVNPFKALYNRIEMKQVEALVEASKEEVKATAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQPLIGRLTVMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDDGAKPGQQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GVPS_PRIMG
Sequence: MSLKQSMENKDIALIDILDVILDKGVAIKGDLIISIAGVDLVYLDLRVLISSVETLVQAKEGNHKPITSEQFDKQKEELMDATGQPSKWTNPLGS
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.
What are the official names of this protein?
Gas vesicle protein GvpS.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle. Note=When the gvp locus is expressed in E.coli gas vesicles are made.
Protein: RL30_XANC8
Sequence: MAKDTGKTVKVRLVRGLRGTQSRHRLSVHALGLNKINDVRELKDSPQVRGLINTVHYLVKVED
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: Y3888_PECAS
Sequence: MLITISPAKTLDYTSPLATTRYTQPELLDYSSQLISVCKKLTPAHIASLMSISDKLADLNAGRFSEWHPDFTPENARQALLAFKGDVYTGLAAESFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGTKLENKAGKDLYSFWGDTITEKLNQALHAQGDDVLINLASDEYFKAVKPKNLNARLIKPVFLDEKNGKFKVISFYAKKARGLMSRFIIQNRLTQPEQLKAFNLEGYAFEAADSSANELVFKRHEQ
What are the official names of this protein?
UPF0246 protein ECA3888.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.