PharMolix/UniProtQA huggingface dataset:
Protein: MSGN1_HUMAN
Sequence: MDNLRETFLSLEDGLGSSDSPGLLSSWDWKDRAGPFELNQASPSQSLSPAPSLESYSSSPCPAVAGLPCEHGGASSGGSEGCSVGGASGLVEVDYNMLAFQPTHLQGGGGPKAQKGTKVRMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQTLKYTIKYIGELTDLLNRGREPRAQSA
What is the function of this protein?
Involved in specifying the paraxial, but not dorsal, mesoderm.  May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity).
What are the official names of this protein?
Mesogenin-1, Paraxial mesoderm-specific mesogenin1, pMesogenin1, pMsgn1.
What are the subcellular locations of this protein?
Nucleus.
Protein: FNBA_STAAR
Sequence: MKNNLRYGIRKHKLGAASVFLGTMIVIGMGQDKEAAASEQKTTTVEENGNSATDNKVSETQTTTTNVNTIDETQSYSATATEQPSNATQVTTEEAPKAVQAPQTAQPANVETVKEEVVKEEANPQVKETTQSQDNSGDQRQVDLTPKKATQNQVAETQVEVAQPRTALESKPRVTRSTDVAEAKEASDAKVETGTDVTSKVTVEDESKIEAPKGNNVQPHEGQRVVLKYKLKFQDGLKTGDYFDFTLSNNVNTHGVATTRKVPDIKNGSLVMAKGQVLDNGRIRYTFTDYIKDKVNVTANLEINLFIDPKTVQSNGQQTITSKLNGKETSGTMQITYKDGVKNQYTNVNGSIETFDKEKNKFTHVAYIKPINGNNSDSVTVTGMLTQGSNENGTQPNVKIYEYVGVENGLPQSVYANTVDSTQLKDVTNQMGDKLKVQNNGSYSLNFDKLDKTYVIHYTGDYLNGTSEVNFRTQLTGYPENRYKTYYYYNNGYTLTWDNGLVLYSNKANGDGKYGPIVDSNNFEFSEDSGNGSISGQYDAKQIIETEENQDNTPLDIDYHTAIDGEGGYVDGYIETIEETDSSAIDIDYHTAVDSEAGHVGGYTESSEESNPIDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTVEDTKEYTTESNLIELVDELPEEHGQAQGPVEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIIDIDFDSVPQIHGFNKHNEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPKVSGQNEGQQTIEEDTTPPTPPTPEVPSEPGTPTPPTPEVPSEPGKPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKQKQAKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNHKA
What is the function of this protein?
Promotes bacterial attachment to multiple substrates, such as fibronectin (Fn), fibrinogen (Fg), elastin peptides and tropoelastin.  This confers to S. aureus the ability to invade endothelial cells.  Promotes adherence to and aggregation of activated platelets (By similarity).
What are the official names of this protein?
Fibronectin-binding protein A.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A (By similarity).
Protein: CM3C_CONAO
Sequence: VCCPFGRCHQICQCCER
What are the official names of this protein?
Conotoxin ar3c.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAK_ACIAC
Sequence: MGKIIGIDLGTTNSCVAIMEGNTTRVIENSEGARTTPSIIAYQEDGEILVGASAKRQAVTNPKNTIYAAKRLIGRKFEEKEVQKDIDLMPYTIAKADNGDAWVEVRGNKLAPPQISAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAFGLDKQEKGDRKIAVYDLGGGTFDVSIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQRIIDYIIAEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSSAATDINLPYITADASGPKHLNIKLTRAKLESLVEELIERTIAPCRTAIKDAGISVSDIHDVILVGGMTRMPKVQEKVKEFFGKEPRKDVNPDEAVAVGAAIQGQVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMITKNTTIPTKFAQTFSTADDNQPAVTIKVFQGEREIASANKLLGEFNLEGIPPAGRGVPQIEVTFDIDANGILHVSAKDKGTGKENKITIKANSGLSEDEIQKMVKDAELNAADDKKKLELVQARNQGEAAVHSVTKSLSEHGDKLEAGEKETIEAAVKDLEAALKGEDKAAIEEKTNALMAASQKLGEKMYADAQAAAAAAGAGAEAGPAAGQAASSAGGASSAPHDDNVVDAEVKEVKKG
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FTSK_STRPQ
Sequence: MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNIGSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMPKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTIDLFVPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQTN
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the difSL recombination site, which is located within the replication terminus region.  Required for activation of the XerS recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: CCA_EDWI9
Sequence: MKTYLVGGAVRDKYLQLPTQDRDWVVVGAAPQTLLAQGYQQVGKDFPVFLHPRSKEEYALARTERKAGQGYTGFSTYFAPDVTLEQDLLRRDLTINAMAEDDEGQLIDPYGGLQDLQQRQLRHVSEAFVEDPLRVLRVARFAARFAPLGFEVAAPTLALMQQMSQQGELAHLTPERVWLETEKALSGPVPQVYFQVLRDCGALAVLFPEIDRLFGVPAPAQWHPEIDTGIHTLLTLAMASHLSDDVAVRFAALTHDVGKGLTNPNFWPHHHGHGPAGVRLVREMCQRLRTPNPVRDLALLVAEYHDLIHTVERLRPATLLKLLDTIDVWRRPQRLQQMILCSEADARGRTGLEDQPYPQAGYLRAAYHQAAQVAVCNVITDGFQGAAIREELQTRRLQALKSWKAAQEAALNAE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RPIA_CHLTB
Sequence: MSKQPENSFSSDKFFPIKQKLALEAVALVEPGMCVGLGSGSTAREFILALGDRVRTERLVITAVASSRISQLLAEAVGIPLLDHSLLQDVDLVVDGADEVDPCLRMIKGGGGALFREKILLQSGKRNVILVDERKLVPTLGKFSLPIEIAPFGCSSVQRILNKQGYFGEWRETSAGERFITDNGNYIYDVRTPDSYANPEEDMIRLLQIRGIIDVGFVIAKAEVWVGYADGSIVRKKEHNEY
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: LIPA_BUCAI
Sequence: MKKNKDVLLKNKILKKLNIINIKNLDNIKEKLKKPDWIKIKIPVNTSRIYQIKNALRKNNLYSVCEEAHCPNLSECFNNGTATFMILGSICTRNCPFCAVFHGRPNPVNVEEPQKLSDTIFDMGINYVVITSVVRDDLYDGGAEHFVNCIKAIKNKNQVKIEILVPDFRGRIELILNIFNKALPDIFNHNIENVPRLFKKIRPGANYQRSLLLLESFKKKYCSVLTKSGLMLGLGEKDVEIIQVMKDLYSSGVTLLTVGQYLQPSIHHLPVKRYIPLSEFENIKKEALSIGFTNAFCGPFIRSSYHASFQSHLPIKNNDINNI
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIC_SALBE
Sequence: MAQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin, Phase 1-I flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: GPDA_HELP2
Sequence: MEIAVFGGGAWGRALAFAFGEKNEVKIISRRDLNEPLKKLNDALISKGSAPIEQVDLQRGLKATLYVIAISVQHLREWFQNASLPKNAKVLIASKGIEVLNRAFVSEIAKDFIDPNSLCFLAGPSFAAEIIQGLPCALVIHSNNQALALEFANKTPSFIRAYAQQDIIGGEIAGAYKNVIAIAGGVCDGLKLGNSAKASLLSRGLVEMQRFGAFFGGKTETFLGLSGAGDLFLTANSILSRNYRVGLGLAQNKPLEVVLEELGEVAEGVKTTNAIVEIARKYGIYTPIASELALLLKGKSVLESMNDLIRRA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_PROM9
Sequence: MRILLAAAECAPMIKVGGMGDVVGSLPPSLIKLGHDVRVIIPGYGKLWSLLEVSNEPVFRANTMGTDFAVYEAKHPIHNYVIYLVGHPIFDSDQIYGGENEDWRFTFFASATSEFAWNCWKPQVLHCHDWHTGMIPVWMHQDPEISTVFTIHNLKYQGPWRWKLEKMTWCPWYMHGDHTMAAAMLYADRVNAVSPTYADEIKTHEYGESLEGLLNYISGKLRGILNGIDLDEWNPAKDPVLPAKFSINNLKNRTENKKILQREMGLEVNPKKYLLGMVSRLVDQKGVDLLLQVSRRLLAYTDSQIAVLGTGDRYLESGLWQLALDYPGRFSVFLTYDDSLSRLIYGGSDAFLMPSRFEPCGISQLLAMRYGSVPIVRRVGGLVDTVLPHDPENNSGTGFCFDRFEPIDFYTSLVRSWEAFRHKDSWELLQKRAMSQEFSWQRSALEYEMMYKDVCGIKEPSPDVAEVEKFSYGQSADPSLKKG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: AMY_PSEHA
Sequence: MKLNKIITTAGLSLGLLLPSIATATPTTFVHLFEWNWQDVAQECEQYLGPKGYAAVQVSPPNEHITGSQWWTRYQPVSYELQSRGGNRAQFIDMVNRCSAAGVDIYVDTLINHMAAGSGTGTAGNSFGNKSFPIYSPQDFHESCTINNSDYGNDRYRVQNCELVGLADLDTASNYVQNTIAAYINDLQAIGVKGFRFDASKHVAASDIQSLMAKVNGSPVVFQEVIDQGGEAVGASEYLSTGLVTEFKYSTELGNTFRNGSLAWLSNFGEGWGFMPSSSAVVFVDNHDNQRGHGGAGNVITFEDGRLYDLANVFMLAYPYGYPKVMSSYDFHGDTDAGGPNVPVHNNGNLECFASNWKCEHRWSYIAGGVDFRNNTADNWAVTNWWDNTNNQISFGRGSSGHMAINKEDSTLTATVQTDMASGQYCNVLKGELSADAKSCSGEVITVNSDGTINLNIGAWDAMAIHKNAKLNTSSASSTESDWQRTVIFINAQTQSGQDMFIRGGIDHAYANANLGRNCQTSNFECAMPIRHNNLKNVTTSPWKANDNYLDWYGIENGQSSEAEGSATDWTTNVWPAGWGAEKTVNTDGFGVTPLNIWGEHYWMLDVDMDCSKAVNGWFELKAFIKNGQGWETAIAQDNAPYTSTNHMAQCGKINKFEFNNSGVVIRSF
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_YERPE
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: IOLG_THEMA
Sequence: MRIGVIGLGRIGTIHAENLKMIDDAILYAISDVREDRLREMKEKLGVEKAYKDPHELIEDPNVDAVLVCSSTNTHSELVIACAKAKKHVFCEKPLSLNLADVDRMIEETKKADVILFTGFNRRFDRNFKKLKEAVENGTIGKPHVLRITSRDPAPPPLDYIRVSGGIFLDMTIHDFDMARYIMGEEVEEVFADGSVLVDEEIGKAGDVDTAVVVLRFKSGALGVIDNSRRAVYGYDQRIEVFGSKGRIFADNVRETTVVLTDEQGDRGSRYLYFFLERYRDSYLEELKTFIKNVKSGEPPAVSGEDGKMALLLGYAAKKSLEEKRSVKLEEVIG
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of myo-inositol (MI) to 2-keto-myo-inositol (scyllo-inosose), and thus probably functions in a myo-inositol degradation pathway together with IolM, IolN and IolO.  Has no activity with scyllo-inositol and much reduced activity (78-fold lower catalytic efficiency) with 1D-chiro-inositol.
What are the official names of this protein?
Myo-inositol 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: MTMR8_HUMAN
Sequence: MDHITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEKLPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSKEMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKVRDEPPEEICTCSQLGNILSQHLGSPLTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCCEIVGSLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDTGISKASTKEADYSKHQ
What is the function of this protein?
Phosphatase that acts on lipids with a phosphoinositol headgroup (PubMed:22647598, PubMed:26143924).  Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (PubMed:22647598, PubMed:26143924).  In complex with MTMR9, negatively regulates autophagy (PubMed:22647598).
What are the official names of this protein?
Myotubularin-related protein 8, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Nucleus envelope.
Protein: ZN428_HUMAN
Sequence: MTETREPAETGGYASLEEDDEDLSPGPEHSSDSEYTLSEPDSEEEEDEEEEEEETTDDPEYDPGYKVKQRLGGGRGGPSRRAPRAAQPPAQPCQLCGRSPLGEAPPGTPPCRLCCPATAPQEAPAPEGRALGEEEEEPPRAGEGRPAGREEEEEEEEEGTYHCTECEDSFDNLGELHGHFMLHARGEV
What are the official names of this protein?
Zinc finger protein 428, Enzyme-like protein PIT13.
Protein: CLPS_SALG2
Sequence: MGKTNDWLDFDQLVEDSVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMFAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: TOLB_RHILO
Sequence: MRSFLKPLLTIAAMALGMTAVIPMPAWALVELNVNKGNVEPLPIAITDFQGGDALGAQISQIVTADLKRSGLFAPIDKSAFIEKISNPDAAPRFDDWKVINAQALVTGSVSKEADGRIRAQYRLWDTFAGQQMSGEQFFANDANQRRVAHIIADAIYERLTGEKGYFDTRVVFIDESGAKNARKKRLAIMDQDGANVRYLSDGRSIVLTPRFSPNRQEITYMSYESGQPRVYLLQIETGQRELVGNFPGMTFAPRFSPDGQKVIMSLLRDDGNSNIFAMDLRSRSTTRLTNSTAIDTSPSYSPDGSKVVFTSDRGGRAQIYVMGADGSGQTRISFGDGVYSTPVWSPRGDLIAFTKQTGGEFQIGVMKTDGSGERILSSGFQQEGPTWAPNGRVLMFFRDSNGGPKLVSVDLTGRNEQPIPTANFASDPAWSPLLE
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DNLI_PYRHO
Sequence: MKYIELAQLYQKLEKTTMKLIKTRLVADFLKRVPEDHLDFIPYLILGDVFPEWDERELGVGEKLLIKAVSMATGVDPKEIENSVKDTGDLGESIALAIKRRKQKSFFSQPLTIKRVYQTLVKIAETTGEGSQEKKMKYLANLFMDAEPLEAKYLARTVLGTMRTGVAEGLLRDAIALAFHVKVELVERAYMLTSDFGFVAKIAKAEGNEGLEKVTIQLGKPIKPMLAQQAANIKEALLEMGGEAEFEIKYDGARVQVHKDGEKVIIYSRRLENVTRAIPEIVEAIKEAIEPEKVIVEGELVAIGEEGRPLPFQYVLRRFRRKHNIEEMMKKIPLELNLFDVLYVDGKSFVDTKFIERRKKLEEIVKPNGKIKVAENLITKNAEEAEKFYKRALEMGHEGLMAKRLDAVYEPGNRGKKWLKIKPTMENLDLVIIGAEWGEGRRAHLFGSFILGAYDPETGEFLEVGKVGSGFTDDDLVEFTKMLKPLIVKEEGKRVVIQPKIVIEVTYQEIQKSPKYRSGFALRFPRYVALRDDKGPEDADTIERIAQLYELQERIKGKV
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: HIS7_PROMT
Sequence: MEKTREGEIRRETKETDVFVKIDLDGSGKCSANTGIGFLDHMIQQLSSHGLFDIEVRANGDTHIDDHHTNEDVGIAIGQALSKALGDRVGIKRFGHFLAPLDEALIQVVVDCSGRPHLSFSLDIPSQKVGTYDTELVKEFFGAVVSNGGLTLHIRQLAGNNTHHIIEATFKSFARALRMATEIDPRRSSQIPSSKGVLEQAGQ
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEA_SHEPA
Sequence: MSNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPDCKIGLNEMAKDMVKSGVALPVLVRFPQILHHRVNSVCQAFNQAINKYQYENDYLLVYPIKVNQQQTVVEEILASQVAKEVPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIRLALIGEKLGHKVYIVLEKMSELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVINSLKQENMLESLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGASVKCFDVGGGLAVDYDGTRSQSSHSMNYGLTEYANNIVSVLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEAYKPEDIQPPAEDAPQLLHNMWQSWIEVSGKADQRALIEIYHDCQSDLTEVHSLFAVGQLGLAERAWAEQVNLRVCYELQGSMSAKYRFHRPVIDELNEKLADKFFVNFSLFQSLPDAWGIDQVFPVMPLSGLDKAPESRAVMLDITCDSDGTVDQYVEGQGIETTLPVPAWTQESPYLIGFFLVGAYQEILGDMHNLFGDTNSAVVRLDDDARTNVESVLAGDTVADVLRYVNLDAVSFMRTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: HUTH_HUMAN
Sequence: MPRYTVHVRGEWLAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFTSVDDAHFLVRRCKGLGLLDNEDRLEVALENNEFVEVVIEGDAMSPDFIPSQPEGVYLYSKYREPEKYIELDGDRLTTEDLVNLGKGRYKIKLTPTAEKRVQKSREVIDSIIKEKTVVYGITTGFGKFARTVIPINKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLETLKQVIEMFNASCLPYVPEKGTVGASGDLAPLSHLALGLVGEGKMWSPKSGWADAKYVLEAHGLKPVILKPKEGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHALRPHRGQIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKNIITTELNSATDNPMVFANRGETVSGGNFHGEYPAKALDYLAIGIHELAAISERRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDIEAAHRLLLEQKVWEVAAPYIEKYRMEHIPESRPLSPTAFSLQFLHKKSTKIPESEDL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
Protein: EF1B_METHJ
Sequence: MGDVALIIKVMPESPEVNRETIVATIKEKFPRVQDIREEPIGFGLVAIKVALVVPDAEGQTETIEATLNAIDGVERAEIVESTLV
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: MNME_NATTJ
Sequence: MTEDTIAALSTPPGEGGIAVIRVSGPDSQNKVKQIFRSSRTDGNFNNKKMYHGQIVSPETNRILDEVLVVFMNKPYTYTCEDVVEIHCHGGMVPVKEILQLLFSYGIRPAEPGEFTKRAFLNGRLDLTQAEGVMDLITSKTNNLKNVAINQLQGNLKQKIDRLRDDLVSVMANLEARIDFPDEDIDVEDYHELKHRIDNAKVDINNLIASYDKGKIIREGIKTVIVGRPNVGKSSLLNLLLGEERAIVTEIPGTTRDVLEEVINLKGIPLRIIDTAGIRESEDKVEQIGVKRTRDSMEQADIILVVIDSSQELSQEDKQILTMAQDKTSLLVLNKTDLHEKLDIDEIDKLVSQIPKVRISALKEEGLDKLEEHISELVFGGQVMQTEELVITKARHFHSLDKVKEALSSAEENIKAEMSEDLIAIDIKEAYDYLGEITGETASEELVDRIFNDFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_ANTAG
Sequence: MTIRSPEPEVKIVVEKDPVKTSFEKWAKPGHFSRTLAKGPSTTTWIWNLHADAHDFDSHTNDLEEVSRKVFSAHFGQLAIIFIWLSGMYFHGARFSNYEAWLGDPTHIKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGFFQIWRASGITSELQLYSTAIGGLIFAALMLFAGWFHYHKAAPKLVWFQDVESMLNHHLAGLLGLGSLAWAGHQVHVSLPINELLDAGIDPKEIPLPHEFILNRDLLAQLFPSFAKGLTPFFTLNWSEYSDFLTFRGGLNPVTGGLWLTDTAHHHLAIAVVFLVAGHMYRTNWGIGHSIKEILEAHKGPFTGEGHKGLYEILTTSWHAQLALNLAMLGSLTIIVAHHMYSMPPYPYLAIDYSTQLSLFTHHMWIGGFTIVGAAAHAAIFMVRDYDPTSQYNNLLDRVLRHRDAIISHLNWACIFLGFHSFGLYIHNDTMSALGRPEDMFSDTAIQLQPIFAQWVQNTHVLAPNLTAPNATASTSLTWGGGDLVAVGGKVALLPISLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSLSNQGVVTHITGGNFAQSSITINGWLRDFLWAQAAQVIQSYGSSLSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIVQGRAVGVAHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: MMP3_RAT
Sequence: MKGLPVLLWLCTAVCSSYPLHGSEEDAGMEVLQKYLENYYGLEKDVKQFTKKKDSSPVVKKIQEMQKFLGLKMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKNHISYRIVNYTLDLPRESVDSAIERALKVWEEVTPLTFSRISEGEADIMISFAVEEHGDFIPFDGPGMVLAHAYAPGPGTNGDAHFDDDERWTDDVTGTNLFLVAAHELGHSLGLFHSANAEALMYPVYKSSTDLARFHLSQDDVDGIQSLYGPPTESPDVLVVPTKSNSLDPETLPMCSSALSFDAVSTLRGEVLFFKDRHFWRKSLRTPEPGFYLISSFWPSLPSNMDAAYEVTNRDTVFILKGNQIWAIRGHEELAGYPKSIHTLGLPETVQKIDAAISLKDQKKTYFFVEDKFWRFDEKKQSMDPEFPRKIAENFPGIGTKVDAVFEAFGFLYFFSGSSQLEFDPNAGKVTHILKSNSWFNC
What is the function of this protein?
Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans.  Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9.  Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway.  Acts also intracellularly.  For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage.  In addition, plays a role in immune response and possesses antiviral activity against various viruses.  Mechanistically, translocates from the cytoplasm into the cell nucleus upon virus infection to influence NF-kappa-B activities.
What are the official names of this protein?
Stromelysin-1, SL-1, Matrix metalloproteinase-3, MMP-3, PTR1 protein, Transin-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.