PharMolix/UniProtQA huggingface dataset:
Protein: CH60_RHIWR
Sequence: MAAKDVKFSRDARERILRGVDILADAVKVTLGPKGRNVVIDKSFGAPRITKDGVTVAKEIELKDKFENIGAQLVREVASKTNDLAGDGTTTATVLAQAIVREGLKSVAAGMNPMDLKRGIDLAVTKVVENLKARSKPVAGSNEVAQVGIISANGDKEVGEKIAEAMDKVGKEGVITVEEAKGLEFELDVVEGMQFDRGYLSPYFITNPEKMQVELTDPYILIHEKKLSNLQSILPILEAVVQSGRPLLIIAEDIEGEALATLVVNKLRGGLKVAAVKAPGFGDRRKAMLEDIAILTNGELISEDLGIKLENVTIGMLGTAKRVTIDKDNTTIVDGAGAADAIKGRVEAIRKQIEITTSDYDREKLQERLAKLAGGVAVIKVGGATEVEVKERKDRVDDALHATRAAVEEGIVPGGGTALLYATKALDGLKGANDDQTRGIDIIRRAISAPVKQIAQNAGQDGAVVAGNLLRENDETKGFNAATDVYENLVAAGVIDPTKVVRTALQDAASVAGLLITTEATIAELPEDKAPAMPGGGMGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_SALA4
Sequence: MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIVEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGITFEPIRPYEFTGRGDRIGWVKGIDDKWHLTLFIESGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVKPQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGSRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RIPR3_HUMAN
Sequence: MSVRLRFLSPGDTGAVGVVGRSASFAGFSSAQSRRIAKSINRNSVRSRMPAKSSKMYGTLRKGSVCADPKPQQVKKIFEALKRGLKEYLCVQQAELDHLSGRHKDTRRNSRLAFYYDLDKQTRCVERHIRKMEFHISKVDELYEDYCIQCRLRDGASSMQRAFARCPPSRAARESLQELGRSLHECAEDMWLIEGALEVHLGEFHIRMKGLVGYARLCPGDHYEVLMRLGRQRWKLKGRIESDDSQTWDEEEKAFIPTLHENLDIKVTELRGLGSLAVGAVTCDIADFFTTRPQVIVVDITELGTIKLQLEVQWNPFDTESFLVSPSPTGKFSMGSRKGSLYNWTPPSTPSFRERYYLSVLQQPTQQALLLGGPRATSILSYLSDSDLRGPSLRSQSQELPEMDSFSSEDPRDTETSTSASTSDVGFLPLTFGPHASIEEEAREDPLPPGLLPEMAHLSGGPFAEQPGWRNLGGESPSLPQGSLFHSGTASSSQNGHEEGATGDREDGPGVALEGPLQEVLELLRPTDSTQPQLRELEYQVLGFRDRLKPCRARQEHTSAESLMECILESFAFLNADFALDELSLFGGSQGLRKDRPLPPPSSLKASSRELTAGAPELDVLLMVHLQVCKALLQKLASPNLSRLVQECLLEEVAQQKHVLETLSVLDFEKVGKATSIEEIIPQASRTKGCLKLWRGCTGPGRVLSCPATTLLNQLKKTFQHRVRGKYPGQLEIACRRLLEQVVSCGGLLPGAGLPEEQIITWFQFHSYLQRQSVSDLEKHFTQLTKEVTLIEELHCAGQAKVVRKLQGKRLGQLQPLPQTLRAWALLQLDGTPRVCRAASARLAGAVRNRSFREKALLFYTNALAENDARLQQAACLALKHLKGIESIDQTASLCQSDLEAVRAAARETTLSFGEKGRLAFEKMDKLCSEQREVFCQEADVEITIF
What are the official names of this protein?
RIPOR family member 3.
What is the protein family that this protein belongs to?
Belongs to the RIPOR family.
Protein: UBIG_RICFE
Sequence: MSSIDKKELEKFEKISHNWWNKDGEFGILHRINPIRLEYIIEKITSHYNDISKLEILDVGCGGGLIATPLAAQGFNVTAIDALQSNIETASTYAKENGVKVNYLQSTIEELQSDKLYDVVICLEVIEHVENVQQFILNLVGHIKPNGMAIISTINRTKKAYVLGIIVAEYVLGWVPKNTHDYSKFLKPSEIYEMLTDTDIEIKELKGLVYDPAKNEWKLSNDIDVNYFMCLGRKTNRHCKEITK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: MSCL_BRUSU
Sequence: MLKEFQEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLAGDPKTTLAAAREAGATIAYGNFITLLINFLIIAWVLFLVVKLMNRLKKREEAKPAPAAPSEEVLLTEIRDILAKQQKA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IP3KA_RAT
Sequence: MTLPGHPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEEDVAPASPGPPDREGNWLPAAGSHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLKRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILANLAER
What is the function of this protein?
Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis.
What are the official names of this protein?
Inositol-trisphosphate 3-kinase A, Inositol 1,4,5-trisphosphate 3-kinase A, IP3 3-kinase A, IP3K A, InsP 3-kinase A.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYL_RICCN
Sequence: MNQIEQKWQYIWQEEKAFEVSNASSKPKYYVLEMLPYPSGKIHVGHVRNYSIGDVIARFMTMQGFNVLHPMGWDAFGLPAENAAIKNNSHPKKWTYSNIKNMKKQLKSMGFSYDWSREINSCDPEYYKHEQKFFLELYERNLAYQKESFVNWDPVDNTVLANEQVVDGRGWRSGAIVVKRYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEETTIEVFSTKPETIFGASFIGIAFNHPIIERLVSKTPEILAFITQCSHITRSSELEKAEKEGVFTGLFVTHPFDSNIVLPVIITNFVLMDYGTGAIFGCPAHDECDHELAVKMNLSIKQVIKADMDVQKTAYTEDGILINSDFLNGLTSNEAKQEVIGEFEKLGIGKRSVNYRLKDWGISRQRFWGCPIPMIHCEICGIVPVPYKDLPVTLPDDVNFDGHGNPLDHHPSWKHVNCPKCDKPAVRETDTFDTFFESSWYFTRYCNSNATEMTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQNYVSVREPFKGLFTQGMVLHATYKDEHNNWLYPEEVVKKGNEFFHKESNNRVVQGRIEKMSKSKKNLIDLETMQEQYGADAIRLFVLSDSPPEKDLEWSASGIEGCSRFINKLEYMFKAIDSLKDDVNSEVNKELNRLVHFTIKHVAEDIKHFALNRAIARMRELSNAISAEISKDKIDVKTVRHGFNVLVQLLNPFIPHITEEIWQKLGNKERLYNLSFPAFDESMLELDTYIMAVQVNGKLRDTYEFKTSVSEDEIKQVTVSLPKVQKFLEGKEPKKIILVPRKIVNILV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCO_STAAU
Sequence: MMDMKENDQKRNDMMDMKSHDERKNLNSSQGKNEITFPKVLDPKKDNNGYKSYTLKAQKGKTEFYKGNFSNTLGYNGNLLGPTLKLKKGDKVKIKLVNNLDENTTFHWHGLEIDGKVDGGPSQVIKPGKEKTIKFEVKQEAATLWYHPHPSPNTAKQVYNGLSGLLYIEDDKKNNYPSNYGKNDLPIIIQDKTFVSKKLNYTKTKDEDGTQGDTVLVNGKVDPKLTTKEGKIRLRLLNGSNARDLNLKLSNNQSFEYIASEGGHLEKTKKLKEINLAPSARKEIVIDLSKMKEDKVNLVDNDETVILPIINKEKSTNKDTTPKVDKKIKLEGMDDNVTINGKKFDPNRIDFTQKVNRKETWEIENVKDKMSGMKHPFHIHGTQFKVLSVDGKKPSEDMRGKKDVISLEPGQKAKIEVVFKNTGTYMFHCHILEHEDNGMMGQIKVTK
What is the function of this protein?
May be involved in copper homeostasis and oxidative stress response.  Oxidizes the substrate 3,3'-dimethoxybenzidine in vitro.  Also possesses low levels of phenoloxidase and ferroxidase activities.
What are the official names of this protein?
Multicopper oxidase mco.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_RICCN
Sequence: MNVFLSKYVNGVDKKSRVSVPANYRAVLGKELFNGVIAYPSIRNNCIEVCGISHIEKLRQMIETLDPYSEERDAFETMIFGEAVQLSFDGEGRVILPQSLMKHAGIEEQACFVGKGVIFEIWQPQNFEKYLNAAQKIAHEKRLTLRNAH
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CYB6_PELHO
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPRDQIGYWAVKIVTGVPDAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLVSAVFMLIHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y1800_HELHP
Sequence: MKLYSVAYIPQSYEVLGLVKGSMVQSKHIGRDIMAGLKGIVGGEIKGYTEMLNDARNIATDRMIEEAHALGANGIIGISYVTSSLMSNTSEVLVYGTAVKILS
What are the official names of this protein?
UPF0145 protein HH_1800.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: ACPS_CITBB
Sequence: MIYGTGVDIVEIARFEKFLQQGNDALFDRIFTPSEIEYCSAKKHSAQHYALRFAAKESFLKALGTGLRDGISWKDMEVVNDQLGKPELRLYRRAEELFRQAGLCSCFLSLSHDAGCAVAMVVLER
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLTD2_MOUSE
Sequence: MVMGVSLSPALGRWFRHAIPFAILTLLLLYISIWFFYEWPFPLPAQRTQQSGLRGLKLPSPSPVLGSLLSFPAGVQSCNPERPLPSQTGPAARPLVVPEKEELPCLGPHGALGRMVSPFLACMSPEGDVALSQYLAGWRELLRFLTPLGTVFAFATSEAFNKVTDLEARVHGPNASHYTSLMTMITWERGAGLLQRPGTEPGHSAGSSGSRTLLLLHRALRWSQLCLHRVATGTLGGPDAGTQCGEAYSTALAPHHPWLIRQAARLAILALPSRGRLLQLACPGTGEADARVALARAAGVLEDVYNRTQGLLAGHGLLQLA
What are the official names of this protein?
Glycolipid transfer protein domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the GLTP family.
Protein: IF11_BURL3
Sequence: MAKEELLELDGIVDEVLPDSKYRVTLENGVVVGAYASGRMRKNHIRILAGDRVTLELSVYDLTKGRINFRHKDANSPRPPRTGQPRR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTE_VIBVU
Sequence: MTNSLFRQSFLSDTLNMQQSVEAKATTLSNGVRLQLHQRGVLEVIPANNSAETKNIILSSGIHGDETAPMELIDKIVHDIETGFQDVQARCLFIIAHPEATNAHTRFIEENLNRLFDEKEHQPSKELVIADQLKLLVKAFFDNTPVESRWHLDLHCAIRASKHYSFAISPKTRHPTRSKALVDFVNHSHVEALLLSNSPSSTFSWFSAEYYSAQALTMELGRVARIGENELERFTALDLTMRDLIAEVTPEHLPKPAITYRVSRTIVRLHQDFDFRFDDQVENFTSFMHGEVFGHDGDKPLMAKNDNEAIVFPNRNVAIGQRAALMVCEVKARFEDDQLVYD
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: Y1821_SHEWM
Sequence: MSFDKKLLEIVACPVCKGKLDYDKAKQQLICKLDRLAYPINDGIPVLLENKAESWEEA
What are the official names of this protein?
UPF0434 protein Swoo_1821.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: RS12_FRACC
Sequence: MPTIQQLVRKGRQDKVEKTKTPALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVRLNSGIEVTAYIPGVGHNLQEHSIVLVRGGRVKDLPGVRYKIVRGALDTQGVRNRKQARSRYGAKKEKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NPL4_AJECN
Sequence: MAPARPILLRFESRNGQFRLTVNPTDEFPSLLPKVLDNLPKNTAPPSIVLSNKPIGTGGQERNISTLKGVTIQRVGLSHGDKLFIGYEEETAVVNGSSSEHPSSISKSQNAPRRLDGVAVRQQEQAPPVPTPTSETLIKNPWEAVKQSPLDDRLDRKDGKISRGLDHKMCRHGPKGMCDYCMPLEPYAPEYLAEKKIKHLSFHSYLRKINSSTNKPELKSSYIPPLSEPDYRVKRDCPSGHPAWPEGICTKCQPSAITLQPQPFRMVDHVEFSSPDLINSLLDFWRKSGTQRLGFLYGTYEEYTEVPLGIKAVVQAIYEPPQVGEVDGVTLHEWGNEKDVDEVAKFCGLEKIGVIFTDLLDAGAGDEIVFAAQLQARYPKATKWSETGRFGSNFVTCVLSGDEDGAISISAYQASNSAVEMVKADIIEPSADPGVMLVQQENHSDDDASKARYIPEVFYRKVNEYGANVQENAKPSFPVEYLLVTLTHGFPTDPDVMFNNSTFPIENREVIGESQDLRMLADKLVSHGDPNKTICGVSDFHLLCFLNSLGILNKDEEFLLCTVARSHDTADGMQLINTSGWATLVTILQESGERPPKRSWPFQSQTFISSHQRSKHPQAPKSEHPQSDSEQLAKRFKGASLG
What is the function of this protein?
Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus.  Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
What are the official names of this protein?
Nuclear protein localization protein 4.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes mainly at the nuclear periphery and the endoplasmic reticulum membrane.
Protein: GATA_METST
Sequence: MKVIEKVEAIKQQEITATENLEQMYSTIEEKNDDINAFVQLDIEKARKTAEDIDKRIKNNEETGKLAGLVIGIKSNINVEDFIISAASPTLKNYYGSYNATVINRILDEDGVIIGLTNMDEFAAGSSTETSMYGPTNNPKAPGHIPGGSSGGSAAAIAANMCDITLGSDTGGSIRNPASHCGVMGFKPTYGMVSRQGLLDLAMSLDQIGPFANDTTGIGLMLNVICGYDPYDTTTINKQPEDFLKDTTNSTLEGQTIGVVKEFMDITDDKITSQINKSIDDMTSLGAEIKELSFEDINLGLPTYYLINYVEFFSATRKYDGRKYGERIEEVCGAEVARRIEIGSYISQKEFSGKYYNKALQARSLIRNEFNELLNDVDVIAGPTVPKLPHKIGEEIETMDMYAYDVLTVLANITGIPASSMNSGLVDNIPVGLQLQAKPEDDHKILSTMSALENN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PYRD_ALIFM
Sequence: MLYRIARAGIFKLDAEKAHDLAIQNFKRFNGTPLDIFYRQNLASKPVEVMGIKFKNPVGLAAGLDKNGECIEAFGAMGFGFVEVGTVTPRPQSGNDKPRLFRLIEAEGIINRMGFNNLGVDNLVENVKKAKYDGVIGINIGKNKDTPIEKGTEDYLICMEKVYQYAGYIAINISSPNTPGLRTLQYGEALDDLLSQLKEKQKELAEKYGKYVPVALKIAPDLEDDELTQIAESLIKYKIDGVIATNTTLDRSMVEGMKHAEEMGGLSGRPVQTRSTEVVRRLKELLGDNLPIIGVGGIDSYVAAKEKMVAGAELVQVYSGFIYKGPGLVRDIVNNI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEXA_VIBVU
Sequence: MKPLTPRQQQVFDLIKSKIEVTGMPPTRAEIARELGFRSANAAEEHLKALARKQVIEIVPGASRGIRILLEEEAANDEPGLPLIGRVAAGEPILAQEHVEMHYQVDPSMFRPQADFLLRVHGESMKDIGIMDGDLLAVHKTQDVRNGQVVVARVEDDVTVKRLERKGSTVLLHAENEEFAPIEVDLTSQQLTIEGIAVGIIRNTDWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: GRCA_SALDC
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKPGFAEDEVVAVSKLGEIEYREIPMEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: LIVM_SALTY
Sequence: MKPMHIAMALFSAAMFFVLAGVFMGVQLELDGTKLVVDTAADIRWQWIFIGTAVVFFFQLLRPMFQKAVKHVSGPKFILPAIDGSTVKQKLFLMALLVIAVAWPFMVSRGSVDIATMTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYYGLGFWTCLPLAGLVSAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGGPNGISQIPKPTLFGLEFSRSTREGGWDTFSNFFGVKYDPSDRVIFLYLVALLLVVLSLFVINRLLRMPLGRAWEALREDEIACRSLGLSPTRIKLTAFTISAAFAGFAGTLFAARQGFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAVLLVVSRELMRDFNEYSMLMLGGLMVLMMIWRPQGLLPMTRPQLKLKSGQAKGEQA
What is the function of this protein?
Part of the binding-protein-dependent transport system for branched-chain amino acids.  Probably responsible for the translocation of the substrates across the membrane.
What are the official names of this protein?
High-affinity branched-chain amino acid transport system permease protein LivM, LIV-I protein M.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_UREU1
Sequence: MSRYTGSIYKKSRRLGFSLLENNKEFNSGKKRTYGPGQHGNKKVKLSNYGQQLVEKQKLMFLYGLNDRQFRRLYRVALGRPGVLTLNLLQVLESRLDSLVYRAGFAPTRRAARQLVNHSHVLVNGKKVNIPSALVEVGSTIALKEKSLEMPLIKNTLNKPADFIELVDKDKKVAKLSRLPERSELPADVNEAYVVEWYNRLM
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL11_MYCUA
Sequence: MAPKKKVAGLIKLQIVAGQANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGTVIPVEITVYEDRSFTFALKTPPAAKLLLKAAGVAKGSAEPHKTKVAKVTWDQVREIAETKKTDLNANDIDAAAKIIAGTARSMGITVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MKAR_COCIM
Sequence: MSHISFKGCSFLSHLDSFQFDISSCQTIAASLVFATGGLFLLSRGLSFLRALFSIFILPGKSLSSFGPKGSWALVTGASDGIGKEYALQIARKGYNIILVSRSASKLSAVASEITSANPNILTKTVSMDFSENNDEDYEKLKDIIKDLDISILINNVGLSHSIPVPFVQTPEKEMKDIIAINCLGTLRVTQLVAPGMMQRKRGLILTMGSFGGLLPTPLLATYSGSKAFLQHWSTALASELEPYNIHVQLVVSYLVTSAMSKVRKASMTIPNPKAFVRSTLNHLGRSGGLFSYSHTSVPYWTHGLMAWGITSFLGAMSKTVLGINKSMHESIRQRALRKAARESGKKAQ
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SYP_SULIN
Sequence: MQITRDKWSKNFSEWFDWVLREGEFYDYGRYPVKGMGVWMPYGFKLRQNIISIIRNLLDSTGHEEVLFPLLIPEDLLRRESTHIKGFEEEVFWVTKGGSEDLDVKLALRPTSEVAITTMENLWLKSYKQLPKKYYQIVSVFRYETKATRPMIRLREITTFKEAHTVHETYDDAQRQVEEAIEIYKKIFNNLAIPYVLSERPEWDRFAGALHTYAFDTIMPDGKVMQIGTVHHLGQNFSRALDFKIQKKDGSLDYPHQTSYGISDRAIASVIAIHGDDHGPILPPSVAPIKVVVVPIPAKNEEGTQQVMKYSIEICEMLNKNNITCVTDQDTEKTPGEKFYIWEIKGVPIRLEIGPRELASSTVFIKRRDNLKSYTVKKEEVVNKVKEVLNEIQEDLRKRAWESLKSRIEYANDIEKAKNILENNSGIVDVPWCGSKECGLKIEELTNARVLGYPIEDRKVNDKCVICKMNAKTVLRVAKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYO20_VIOOD
Sequence: GIPCGESCVWIPCLTSAIGCSCKSKVCYRD
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cycloviolacin-O20.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: PUR7_SALPA
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNHFIMTKLAEAGIPTQMERLLSDTECLVKKLEMVPVECVVRNRAAGSLVKRLGVEEGMELNPPIFDLFLKNDALHDPMVNSSYCETFGWVSQENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLDKMDKDRFRQSLGGLIEAYEAVAHRLGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: ULAG_ECO5E
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_SHESH
Sequence: MTMSVNKSTLVLKVGGALMQCEMGMARLMETAAKMIASGQQLIMVHGGGCLVEEQLTANGMTTEKLDGLRVTPQEQVPVIVGALAGTSNKILQGAAIKAGVTCVGMSLGDGDMVSAKVKDPRLGFVGEVSPKSATYLEFILSQGWMPIVSSIAIDAAGQLLNVNADQAATVLAKLVDGKLVLLSDVSGVLDGKGQLIKSLNRSQVEELTNIGVIEKGMKVKVEAALEVAESMGQPVQVASWRHAEQLIALSNGEAVGTQIQPD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.