PharMolix/UniProtQA huggingface dataset:
Protein: CLPB_CLOPE
Sequence: MNADKMTLRVQQSLNDAYEIAVKYNNQQLDIIHLFSALVNQKDGLIPNIFEKMGVNIDSLKRDIHVQIDRMPKVLGEAAQSSGVTATRRINEVLIKAEEISKQFEDSYISVEHVMLAMIDIDKNGAVGEILRKNNITKDGFLKVLNEVRGSQRVDSQDPEGTYEALDKYGTNLIELVKQHKLDPVIGRDEEIRRAVRILSRKTKNNPILIGEPGVGKTAIVEGLAERIVRGDVPEGLKDKVIISLDMGALIAGAKYRGEFEERLKAVLKEVQSSEGKILLFIDEIHTIVGAGKTDGAMDAGNLIKPMLARGELHCIGATTFDEYRQYIEKDKALERRFQPVIVEEPTVEETVSILRGLKERFEIHHGIRIHDSAIVAAAKLSHRYIQDRYLPDKAIDLIDEAGAMIRSEIDSLPTELDIIRRKILMLETEKEALSKENDDASKERLVALEKELAELQDKNDEMTIKYEKEKSHISAVRDLKAELDEARGLAEKYEREYDLNKVAELKYGKIPELERKIKEQEASMEKDNENALLKEEVTENEISEIISKWTGIPVTKLVESEREKLLRLEEELRERVIGQDEATTAVANAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKTLARNLFDSEDNIVRIDMSEYMEKHAVSRLIGPPPGYVGYEEGGQLTEAVRRNPYSVILFDEIEKAHDDVFNLFLQILDDGRLTDNKGKTVDFKNTIIIMTSNIGSGYLLENKSGEGIEDDIRENVMNEMKLRFKPEFLNRVDDIIMFRPLSSEGIKKIIDIFLRDVENRLRERNITLEVTDRAKEILAEEGYDPVYGARPLKRYISNVLETEIAKKIIAGEIYDGSVALIDGVDGKIIVSRK
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SBH_HEMHA
Sequence: LKCHNKLVPFLSKTCPEGKNLCYKMTLMKMPKIPIKRGCTDACPKSSLLVKVVCCNKDKCN
What is the function of this protein?
This protein lyses red blood cells and has cardiotoxic and hypotensive activities.
What are the official names of this protein?
Three-finger hemachatoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IB cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRB_ESCF3
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_BORRA
Sequence: MSTIKSGDIDKGSFLLFKGMPHIVLEREFSKMGRGGSIVRLKLKNLKNKSVIKETLKGSDTVEEIEVLEVNSQYLYKDNESLIFMDLETYDQFSVNLRDVVNLEDKVLFLQEAEVYSLIKWGNEVIDLKLPPKVAFEVVDAEIAVKGDTVTNAMKNVTLHTDLVVKAPLFINIGDKILVNSETKEYAERVKV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALAE_PECPW
Sequence: MFSPTSRLRSATADTFALVVYCFIIGMAIEIMLSGMSFEQSLSSRLLSIPVNIAIAWPYGLYRDRVLNMAKRHGGDHFLVRSVADLFAYVSFQSPVYAAILWVIGASSAQILTAVTSNLVISMVMGVTYGYFLEYCRRLFRVALP
What is the function of this protein?
Exports L-alanine.
What are the official names of this protein?
L-alanine exporter AlaE.
What is the protein family that this protein belongs to?
Belongs to the AlaE exporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECA_ORITI
Sequence: MLKFIKSIFKTPSDRIIANLKSKIQQVHSAESSLAKLSNIELRNKTNEFKARLANNEPIDNIQYEAFAVVREAAKRTIGIQHYDEQLIGGILLHQGKVIEMSTGEGKTLVATLPSYLNALIGKGVHVVTVNDYLAQRDSDWMGTIHRFLDITVGCITSNTNEHARKIAYNSDITYITNNELGFDFLRDNMQFTNQSKVQRGCNYAIIDEIDSILIDEARTPLIISGPVSDNTSLYPIINKLITKLNKDDYEMDEKLRNVTLTDSGINKLETMLAEINILAPNSNSLYDFENMHLIHYINQSLKAHTLFRRNVDYLVKNGKVIIIDEFTGRTMDSRRYSEGLHQALEAKEKVEIQNENQTLASITFQNYFRMYTKLSGMTGTAMTEATELKEIYDLDVVTVPTHNPVQRIDYNDEIYSTKKDKYSAIIQLIQECYSKGQPVLVGTVSIEKSEELSKLLHSKKIPHNVLNAKHHDKEASIIAQAGRIKAITIATNMAGRGTDIMLGGNAEMLVDQSNLTEEEYQEKLKITKMQIEQEKEQVINAGGLFVIGTERHESRRIDNQLRGRCGRQGDPGQTKFFLSLEDDLMRIFASDRVTKILRTIGLKDGEAIHHPLINRSLATAQQKIEAQNYEIRKNLLKYDNVMNDQRKVIYEQRNEAISSDNVNEILHNLTEELIVETVHKFIPPKSYKEDWNIHELLKEYHHIFNVKLQPASIEATSSSSEVIEYLTKTALDIYKQQEQDYSAKSANEAIKHIFIKTLDQTWKEHLYTLDHLKQGISLRAYGQKDPLNEYKREAFDLFKQMLLHLKYLFIQRVARLHIDLASSPKSTSSLLETSDNNLKGKIITENSMAHKYFGKISRNQLCPCNSGKKFKHCHGALK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RS20_THEM4
Sequence: MPNIKSAKRRVKISERNRLINKAYKTRMKNSIKKVLLALSEGKTKEEVEQLYKIAQSAIDKAAKIGAVHKNEAARRKSRLMSKINKHFAIE
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: BPPS_LYCER
Sequence: QAPWPDTISPP
What is the function of this protein?
This peptide potentiates the effects of bradykinin on smooth muscle, and inhibits the angiotensin-converting enzyme (ACE) in vitro.
What are the official names of this protein?
Bradykinin-potentiating peptide S, BPP-S.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB_NEIMB
Sequence: MITVNTLQKMKAAGEKIAMLTAYESSFAALMDDAGVEMLLVGDSLGMAVQGRKSTLPVSLRDMCYHTECVARGAKNAMIVSDLPFGAYQQSKEQAFAAAAELMAAGAHMVKLEGGVWMAETTEFLQMRGIPVCAHIGLTPQSVFAFGGYKVQGRGGKAQALLNDAKAHDDAGAAVVLMECVLAELAKKVTETVSCPTIGIGAGADCDGQVLVMHDMLGIFPGKTAKFVKNFMQGHDSVQAAVRAYVAEVKAKTFPAAEHIFAD
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_THEP1
Sequence: MFKLVSEFEPTGDQPQAIEKLVEGLNRGMRFQTLLGVTGSGKTFTMANVIARVNRPALVISPNKTLAAQLYQEFKAFFPENRVEFFISYYDYYQPEAYIPTKDLYIEKNADINDVIVRMRMSTLKSVRTRRDVVVVASVSCIYATGDPNDFDRMNINLAVGDRIDVLELAERLARIGYQRTEDVSLSGCFRLKGDTVEIYPTYQDEGIRIEFFGDEVDSITLIDRFNRTTLEHLDKIIIYPAVEFITTEEKLKRAVESIREELNERLSELKKQGKILEYERLKQRTLNDIELLETMGYCPGIENYSRHFDGRKPGEPPYTLLDYFDKDFIVFIDESHITVPQLRAMYNGDRSRKKNLVEYGFRLPSAYDNRPLTFEEFLKKTGQIIFVSATPGDFELSISEQVVEQIIRPTGLVDPEVEVRPTAGQVDDLVNEIVKVKERGERALVTVLTKKTAELLSEHLTELGIRSLYLHSELDAIERVEVLKKLRRGDVDVVVGVNLLREGLDLPEVSLVAIMDADVEGFLRSETTLIQIIGRTARNINGKVIMYADRITNAMKRAIEETNRRRRIQLEYNKKHGITPRSVIKPLEIEVFEQFMVKEEPERYGDTVKNIFEMKKTLSPEEYMAVLEEEMYRAASELRYEDAAALRDELFRIREEIKKKKGL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DACT1_HUMAN
Sequence: MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQFNSLDVIADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV
What is the function of this protein?
Involved in regulation of intracellular signaling pathways during development.  Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins.  The activation/inhibition of Wnt signaling may depend on the phosphorylation status.  Proposed to regulate the degradation of CTNNB1/beta-catenin, thereby modulating the transcriptional activation of target genes of the Wnt signaling pathway.  Its function in stabilizing CTNNB1 may involve inhibition of GSK3B activity.  Promotes the membrane localization of CTNNB1.  The cytoplasmic form can induce DVL2 degradation via a lysosome-dependent mechanism; the function is inhibited by PKA-induced binding to 14-3-3 proteins, such as YWHAB.  Seems to be involved in morphogenesis at the primitive streak by regulating VANGL2 and DVL2; the function seems to be independent of canonical Wnt signaling and rather involves the non-canonical Wnt/planar cell polarity (PCP) pathway (By similarity).  The nuclear form may prevent the formation of LEF1:CTNNB1 complex and recruit HDAC1 to LEF1 at target gene promoters to repress transcription thus antagonizing Wnt signaling.  May be involved in positive regulation of fat cell differentiation.  During neuronal differentiation may be involved in excitatory synapse organization, and dendrite formation and establishment of spines.
What are the official names of this protein?
Dapper homolog 1, hDPR1, Dapper antagonist of catenin 1, Hepatocellular carcinoma novel gene 3 protein.
What is the protein family that this protein belongs to?
Belongs to the dapper family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Synapse. Note=Shuttles between the nucleus and the cytoplasm. Seems to be nuclear in the absence of Wnt signaling and to translocate to the cytoplasm in its presence.
Protein: C554_NITEU
Sequence: MKIMIACGLVAAALFTLTSGQSLAADAPFEGRKKCSSCHKAQAQSWKDTAHAKAMESLKPNVKKEAKQKAKLDPAKDYTQDKDCVGCHVDGFGQKGGYTIESPKPMLTGVGCESCHGPGRNFRGDHRKSGQAFEKSGKKTPRKDLAKKGQDFHFEERCSACHLNYEGSPWKGAKAPYTPFTPEVDAKYTFKFDEMVKEVKAMHEHYKLEGVFEGEPKFKFHDEFQASAKPAKKGK
What is the function of this protein?
Involved in ammonia oxidation; accepts electrons directly from hydroxylamine oxidoreductase (HAO).
What are the official names of this protein?
Cytochrome c-554, Cytochrome c554, Hydroxylamine oxidoreductase-linked cytochrome.
What are the subcellular locations of this protein?
Periplasm.
Protein: PIYH2_XYLFT
Sequence: MVGMSRIILNNLFFFRCVVAVFSAHSLVISGAVHAGVQISQSPLHGGGDVPGNLAIVASIEFPTVISVANLADTYTPGVRYVGYFDSNKCYKYHYSSRELDRYFYPVASPRPQANYGCNTTGGVWAGNFLNWAATQTIDPFRSALTGGYRVRDTANETILEKAVMDRAYPGNFPRRTIEGLALTTSVPAQWLRFRMRIDGLGNRMRFTQFPGLSTDPLNTEGQPYDPSRHPLNSNDRGVYEVSVRVKVCDASVGLESNCVAYPSGFYKPEGLVQEYSKRVRYSVFSYKNDDYYLDDGGVLRARQKFVGPKTYYPEQGEKTNPHAEWHPRTGVLYDNPNPEDAKATTHRVGRTIGNSGVINYLNKFSQMETGKNTKGFDPVSELYYTAYRYFKRLGNVPEYSVLTGSVNEKYQQADAFPVITDWDDPIRYACQSNVVLGIGDTHTNFDKNLPGNTNTTGEPVKPQAVRNDRSIDVVKRMAQIFQMEGMRQQDAMTSALAPSFNFLVPGAGNNSAYIAALAYDAHTKDMRPDLEGDQLLTTHWVDVVEGGDYKIPISTNQYWLAAKYGGFQVPAGYDPDKTVNPLSEATWWTNGEYVNGDTKAKRADNFYIAADAEKMVASLKHAFSRIVAEIKGAGTGLSSNSARLETGAVTYQAQFFSGTWRGDLIAYHVDKVTGALTPFWNANFPAWEQRVIKFANATTLQDFTKKNLGQTALASASAQQINYLRGDRSQEGNVPGKLRIRSGIMGDIVNSQPLYVGAPNGRLYTTANFTGASAYAAFAAQQANRVPVVYVGANDGMLHAFDANTGKEIFAFVPRAAMPKLLEYTDQNYGHQYYVDGELTAADIYDTKLGWRSVLVGTLGRGGKGLFALDVTDPSNIRLLWDKTSADIGGLGNTLSKPMIAQTSDGTWSVLLGNGPNSTADNAQLIVMNLLTGHAAQVPVSKTSNNGLSGVFPWSSQSNGITDRVYAGDLLGTLWRFTFSDNAWKVAPLFTATYQGKAQPISATPLGAIERSTGRMWIFFGTGRALSSHDMDNKEVQSWYGLIDQGTTIPGRTRLSQVQIVDEGVVNGYAVRTVSDPKNIGTDGWYMDLISPKSGKQGERMIVSNMFRGAALIGTTRIPDNSDICKLSGSGFVMAINPFTGGRLGQWFFDLNTGGGSGGALNGNPVSGVGVSSAPNSPVFTGNIMQIGADDGTVTSLKTPSSGGLNINRVSWREILRP
What is the function of this protein?
One of the three PilY1 homologs of X. fastidiosa, which are involved in bacterial twitching motility as component of the filamentous type IV pili (T4P).
What are the official names of this protein?
Type IV pilus biogenesis factor PilY1 homolog PD_0502.
What is the protein family that this protein belongs to?
Belongs to the PilY1 family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: MALT_SALHS
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALVTSPAGYGKTTLVSQWAAGKNELGWYSLDEGDNQQERFASYLIAAIQQATGGHCSTSEAMAQKRQYASLTSLFAQLFIELAQWHRPLYLVIDDYHLITNPVIHDAMRFFLRHQPENFTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFNHQEAKQFFDRRLSSPIEASESSRMCDDVAGWATALQLIALSARQNHTSAHHSARRLAGINASHLSDYLVDEVLDNVDVSTRHFLLKSAILRSMNDALIVRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFSYHPLFGSFLRQRCQWELAAELPEIHRAAAESWMEQGFPSEAIHHALAAGDAQMLRDILLNHAWGLFNHSELALLEESLKALPWESLLENPRLVLLQAWLMQSQHRYSEVNTLLARAEQEIKGVMDGTLHAEFNALRAQVAINDGNPEEAERLAKLALDELPLAWFYSRIVATSVHGEVLHCKGDLSQSLSLMQQTEQMARHHDVWHYALWSLIQQSEIQFAQGFLQAAWETQERAFQLIKEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIAVLSTFQPQQQLQCLTLLVQCSLARGDLDNARSQLNRLENLLGNGRYHCDWISNADKVRVIYWQLTGDKKSAANWLRHTPKPAFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQSGRKNDAQRVLLDALQLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPEMEQHRAQRILREINQHHRHKFAHFDEGFVERLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELAVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: RUVB_CLOP1
Sequence: MSERLVTSNEIGIDSTNEYSLRPEKINEYIGQDKVKERLNIFIKAAQRREEALDHVILYGPPGLGKTTLANIIANEMGGNLKITSGPAIERAGDLAAILTTLNTNDVLFIDEIHRLNRSVEEILYPAMEDYVLDIIIGKGAASKSIRLDLPKFTLIGATTRIGMLSSPLRDRFGVLCSMEYYTDEQLKEIIIRSAEILGCHITEEGAFEIAKRSRGTPRIANRLLKRVRDFAEVLYDNEITEEAAKKSLEILEVDGEGFDRIDNKILEAIIDNFNGGPVGIETLAYFVGEELDTIEDVYEPYLLQKGFIVRTPRGRMATDKAYKHLGRVRFNESKIDSKQCTLFEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: KIP2_ASHGO
Sequence: MMMVARVATAEHVGSAGASLPQTPGSRSFALGAHPGPQKRIGGPAQGQTAFITPLVTPDGIYSRPSSPYMQASPLLKGSESGGSAGSPQSPDAPSSASGASVGNAIGSGYTGNVSVAIRIKPSESSTKDPWYASNDRLIHTEFGEFQFDHVFTKGVCNQEVYQALGVPIIDKLFEGYNATIFAYGMTGSGKTFTMSGNKQEPGLIPQCVGNIFDRISSEHHGASLAYEVKVSYLEIYNEKIYDLLNYVDRQAGSTGQPSRNATGLKIRDDSKYGVKVVDLTEQLVSSHEDVMKWIATGDRNRKTGETDFNTRSSRSHAIVLLRLTRYDLKTGSEATSTLSLCDLAGSERAVTQIVRRKEGAFINKSLLALGTVIAKLSMLGSQANGLQPSPAAGHIPYRDSKLTRILQPALTGDSIITTICTIDSKAESSTETTNTVRFASRAKNIALNVRKNEMDSHAEKDTIIQNLRKQLDEQHETIVMLRRSAAAPSGNGSTSPLDSPGVGGTSLSERTHNMEKGLLEVENSILKTKLEHCEKLLDKDMMVLEDPHVREIVEMLPLDIASVLESKVQGMESQLRQYRVYVQKLESDLLKAQRNIITTHSVQFNRQSTANVQEKYGSDVDIELLLEEQEAELMELRNALKRKDKMIEALQSARRLRDSALSPTTTVLLQRKESVIDPRDPQPV
What is the function of this protein?
Required for assembly of the mitotic spindle.
What are the official names of this protein?
Kinesin-like protein KIP2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MOAC_ERWT9
Sequence: MSQLTHINAAGEAHMVDVSTKQESVREARAQAFVVMLPQTLQMIIDGSHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEVTLVAEPAHHRVRIESLCRLSGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIEQCRLLSKSGGKSGDFQAVAND
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: TAL_ALKCK
Sequence: MKFFVDTANINEIKEANELGILDGVTTNPSLVAKEGVDFHERIAEIAKLVPGSVSAEVISLDAEGMIEEGKTLAAISENITVKVPMTVDGLKAVKAFAELGIKTNVTLIFSVPQALLAARAGATYVSPFLGRLDDIGHDGLQLISDIADIFSTHGLPTQIIAASVRHPVHVSEAAKRGAHIATIPLNVIKQLTGHPLTDKGIEKFLADWNKENVEK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_METTP
Sequence: MTFDIFPAVDLRGGRCVQLVQGVPGSEVVSLDDPLVQAVRWADMGADHLHIIDLDGAIEGTRLNAPILRRIVGELEVFVQVGGGIRSRSDVAEVLDTGVDRVILGTMALRDPPVVKELAEEYGPDRIMVALDVRDGRVTSEGWQRTLEFDAIELGIVFESFGAGSILFTNIDTEGQQRGVDPEPTRELVEAVSIPVIAAGGVSSLDDIKLLSDAGAAGAVIGTAIYTGTLNLREALELAKTL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_DEHMB
Sequence: MNTYTVKASDIKRDWHVIDASGRVLGEVAAEAAKYLMGKHKPMFCRNLDCGDYVVIVNAKKITVTGNKLDQKMYYRHSGFPGGFRQEKLGDLLKTKPLFVIEHAVKGMIPRNTLGAQILAKLKVYEGAEHPHASQTGVVSKES
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GSA_PSYA2
Sequence: MSTKNEQLFAQACKHIPGGVNSPVRAFAGVGGTPIFMHRANGSKIYDTEDNAYIDYVGSWGPMILGHAHPKVIDAVKKAADDGLSFGTPTPFETTVADKICEIVPSVEMIRMTSSGTEATMSAIRLARGYTQRDKIVKFEGCYHGHSDSLLVKAGSGMLDIGEPTSKGVPADFAKHTITIPYNDSQAIKDCFEKWGEEIACVILEPIAGNMNMVIPSQEFHDTLREQCTANNSVLIFDEVMTGFRVGLGGAQAHFGIDPDLTCFGKIIGAGLPVGAFGGKKEVMSCIAPLGGVYQAGTLSGNPLAMRAGIAMFEDLTAEGFYDELAVKVDRLVDGFQAAADKHGINLRTNKLGGMFGMFFVTDGDTAVPQNFDEVTECDMEVFNTFFHGMLDRGIYLAPSAYEAGFMSIKHSDEDIDTSIKAADEIFAEMAKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.