PharMolix/UniProtQA huggingface dataset:
Protein: PSBL_ADICA
Sequence: MTQPNPNKQSVEPNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS8_ACTP2
Sequence: MSMQDPIADMLTRIRNGQAANKVAISMPSSKLKVAIASVLAEEGYVESFKIVEGSKPELEITLKYFQNKPVVESIQRVSRPGLRIYKRKDELPKVMGGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MZT2B_HUMAN
Sequence: MAAQGVGPGPGSAAPPGLEAARQKLALRRKKVLSTEEMELYELAQAAGGAIDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQDPAAVSLPTSSVPETRGRNKGSAALGGALALAERSSREGSSQRMPRQPSATRLPKGGGPGKSPTRGST
What are the official names of this protein?
Mitotic-spindle organizing protein 2B, Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B.
What is the protein family that this protein belongs to?
Belongs to the MOZART2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
Protein: MOAC_YERP3
Sequence: MTQLTHINTAGEAHMVDVSAKNETVREARAEAFVDMQAATLAMIIDGSHHKGDVFATARIAGIQAAKKTWELIPLCHPLLLTKVEVKLEAQPEHNRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMIIGPVRLLTKSGGKSGDFKVDI
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: TRPE_BACPU
Sequence: MNSQSNLTQFLKDSESYKTIPIVETITVDTLSPIQIVEKLKQDIVYLLESKDESSSWSRYSFIGLHPFLTLHDDQNKYIARDAAGQKLMQKQELKELLDWMKEQYQIKTPDIDIPFTGGAVGYLSYDLIPTLTSVRPHRSASTIENAHICLPTMIAFDHETNHVHFIQYTQLTGHETEDEKIRAYKEKQKQLEQMIHKLHSKVDMKELILSGNMNEPPSFEHVTSTYEKAQFLKDVEKIKEYIRAGDIFQGVLSQRFDIPVSVSSFELYRVLRIVNPSPYMYFMKLKDRDLVGSSPERLIHAKNGHLEIHPIAGTRKRGTTREEDAELARELLEDEKEKAEHYMLVDLARNDVGRVAEYGSVSVPTFTKVVNFSHVMHIISIVTGKLKRDTHPVDALMSAFPAGTLTGAPKIRAMQLLNEMEPEPRETYGGCIAYIGFDGNIDSCITIRTMSVKNHTASIQAGAGIVADSVPENEWEETCNKAGALLKAIQLAEHIFSEKESVQDESPTISSC
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: HUTU_SHEPA
Sequence: MDKRHDPSRRIIAPTGTELSCKSWLTEAPLRMLMNNLHPDVAERPEDLVVYGGIGRAARDWECYDKIVEVLQRLEEDETLLVQSGKPVGVFKTHNNAPRVIIANSNLVPHWANWEHFNELDKKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVAMAKQHFNGSSAGKWILTGGLGGMGGAQPLAGTMAGYSVLTCEVDETRIDFRLRTKYVDKKATTLDEALAMIDEANKSGKPVSVGLLANAADVFAELVERGITPDVVTDQTSAHDPLNGYLPQGWTLEQAIEMRKTDEAAVVKAAKQSMAVQVKAMLALQAAGAATTDYGNNIRQMAFEEGVENAFDFPGFVPAYVRPLFCEGIGPFRWVALSGDPEDIYKTDAKVKELIPDNPHLHNWLDMARERIAFQGLPSRICWVGLKDRARLALAFNEMVKNGELSAPVVIGRDHLDSGSVASPNRETESMLDGSDAVSDWPLMNALLNTASGATWVSLHHGGGVGMGFSQHSGVVIVADGTDDAAARLGRVLWNDPATGVMRHADAGYDIAKNCAKEQGLDLPMLEKATTEGK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHC5_SCHPO
Sequence: MISRCIKRCYRSGYMIFPPNRLQSTIRSKEEINSSRHKFNIADTSVRKQYNEELVFTKDAKENAEAKKVSSKVKKDRKNHSAAMEGVNINVPGIYRDVYPLPNEDVEMHEAKKKENICKKENLSKTVLVRQLAEIYFANSNKYVVDENGLDDLIQQAFKNPNDVFQPLPSKRDGDNMRLFIETEEEADMTSIKQHAIEVVLQDFQEEQPLEDKRDTIE
What are the official names of this protein?
Uncharacterized protein C19F8.05.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GAR1_DICDI
Sequence: MSFRGGRGGFGGGDRGGRGGGRGGFGGGDRGGRGGFGGGRGGGRGGFGGDRGDRGGYASGENIEIGVFSHVCEEQIVCKLTATEQVPKFNCKVLSSSKNTIGSVDEIFGPINKVFFSVKLDSGVQATSFKENDKIFVDSNSVLPIKIFLEEPKPIAKVPKTPGAGGAGRGGRGGARGGFGGGRGGGAGRGGFGGGRGGSRGGFGGGRGGGSGFGGRGGSRGGRGGGRGGF
What is the function of this protein?
Required for ribosome biogenesis.  Part of a complex which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
What are the official names of this protein?
Probable H/ACA ribonucleoprotein complex subunit 1, Nucleolar protein family A member 1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MENB_STAAS
Sequence: MTNRQWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVSEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
What is the function of this protein?
Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA synthase, DHNA-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
Protein: ENV_RSVSB
Sequence: MEAVIKAVLTGYPGETSKKDSKKKPPATSKKDPEKTPLLPTRVNYILIIGVLVLCEVTGVRADVHLLEQPGNLWITWASRTGQTDFCLSTQSATSPFQTCLIGIPSPISEGDFKGYVSDNCTTLEPHRLVSRGIPGGPENSTTLTYQKVSCLLLKLNVSLLDEPSELQLLGSQSLPNITNITRIPSVAGGCIGFTPYDSPAGVYGWDRREVTHILLTDPGNNPFFDKASNSSKPFTVVTADRHNLFMGSEYCGAYGYRFWEMYNCSQMRQNWSICQDVWGRGPPENWCTSTGGTWVNQSKEFNETEPFSFTVNCTGSNLGNVSGCCGEPITILPPEAWVDSTQGSFTKPKALPPAIFLICGDRAWQGIPSRPVGGPCYLGKLTMLAPNHTDILKILANSSRTGIRRKRSVSHLDDTCSDEVQLWGPTARIFASILAPGVAAAQALKEIERLACWSVKQANLTTSLLGDLLDDVTSIRHAVLQNRAAIDFLLLAHGHGCEDVAGMCCFNLSDHSESIQKKFQLMKEHVNKIGVDSDPIGSWLRGLFGGIGEWAVHLLKGLLLGLVVILLLVVCLPCLLQIVCGNIRKMINNSISYHTEYKKLQKAYGQPESRIV
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp95, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the Alpharetroviruses envelope glycoprotein family.
Protein: SPX3_ARATH
Sequence: MKFGKRIKEQIQESLPEWRDKFLRYKELKNLISSPAPVESIFVGLLNAEIDKFNAFFVEQEEDFIIHHKELQYRIQRLVEKCGHNDEMSRENISEIRKDIVNFHGEMVLLVNYSNINYTGLAKILKKYDKRTRGGLRSPFIQKVLHQPFFKTDLVSRLVREWETTMDAVDPVKVAEAEGYERCAAVTSAAAGEGIFRNTVAALLTMKEMRRGSSTYSAFSLPPLNISDSDNVLRSLHLSSPIPIP
What is the function of this protein?
Plays a positive role in plant adaptation to phosphate starvation and exerts negative feedback regulation of SPX1.
What are the official names of this protein?
SPX domain-containing protein 3, Protein SPX DOMAIN GENE 3, AtSPX3.
Protein: RR15_CUSRE
Sequence: MVKNFSISVISKKENKENRGSIEFQILNFTKKIRRLTSHLKLHKKDFLSQKGLRKILGKRHRLLAYLSKKLKICYKDLIEKLEIRDTKTH
What are the official names of this protein?
30S ribosomal protein S15, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid.
Protein: AT5F1_HUMAN
Sequence: MLSRVVLSAAATAAPSLKNAAFLGPGVLQATRTFHTGQPHLVPVPPLPEYGGKVRYGLIPEEFFQFLYPKTGVTGPYVLGTGLILYALSKEIYVISAETFTALSVLGVMVYGIKKYGPFVADFADKLNEQKLAQLEEAKQASIQHIQNAIDTEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLYRVYKEVKNRLDYHISVQNMMRRKEQEHMINWVEKHVVQSISTQQEKETIAKCIADLKLLAKKAQAQPVM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
What are the official names of this protein?
ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase peripheral stalk-membrane subunit b, ATP synthase proton-transporting mitochondrial F(0) complex subunit B1, ATP synthase subunit b, ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase B chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: ISPG_YERE8
Sequence: MHNESPIIRRKSTRIYVGKVPIGDGAPITVQSMTNTKTTDVAATVAQIKALERVGVDIVRVSVPTMDAAEAFKLIKQQSNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGSEERIRSVVDCARHHNIPIRIGINGGSLEKDIQEKYGEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVYLAVNSYRLLAKQINNPLHLGITEAGGARSGSVKSAIGLGLLLSEGIGDTLRISLAADPVEEVKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDLITPMDVSIIGCVVNGPGEALVSTIGVTGARNHSGFYEDGVRQRERFDNEKMIDQLEAKIRAKASMLDANNRIVINMLEEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RS5_CHLFF
Sequence: MTLSKNSHKEDQLEEKVLVVNRCSKVVKGGRKFSFSALILVGDGKGRLGCGFAKANELTDAIRKGGEAARKNLITIETLDGDSIPHEVLVDQDGAQLLLKPAKPGTGIVAGSRIRLILEMAGIKNIVAKSLGSNNPMNQVKAAFKALLSLSSRKDVLQRRRVTHD
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NBN_CHICK
Sequence: MWKLVPAAGPGEPFRLLVGTEYVVGRKNCAFLIQDDQSISRSHAVLTVSRPETTHSQSVSVPVLTIKDTSKYGTFVNGSKLSGASRSLQSGDRVNFGVFESKFRVEYESLVVCSSCLDVAQKTALNEAIQQLGGLVVNEWTKECTHLIMESVKVTVKTICALICGRPIVKPEFFSELMKAVQSRQQLPTPESFYPSVDEPAIGIDNMDLSGHPERKKIFSGKTFVFLTAKQHKKLGPAVILGGGEAKLMAEERKETSLLVSPEVCVVDVGVTNSQILGSESMRNWTDSILAVLESNNLRAIPEAEIGLAVIFMSTEIYCNPQRQPDNKAVTASTASKVRPVSSQSSTVDETIMPTAAADYSTLNVADTEIEEQTCMEIERTTSQTTRREKVAFQQAAVRENPSTSGTVNAGMLISRVNRTSGFGQKNHPHSPSKILEVDKPRECTPRQQSNSITNYFHVARKRERAEEGEETSLSKQAKLEKKPLPVSECTESSASSAWNSEKEQHGKGNNIQLGRESGELASDKTDIKITFSENPAPKKRKELDDVSEDVETLEMVFESRDLDWEEQTANGDQEAQSNKRKKRCLETKGSRTEEGNTKQREENEMLRKEEVGSVLTLEDKSKIKEESSVSIRNKLINHNKLEDDSSRLPSKLLLTEFRSLVVSCPRSNSPTMRNTKCRGQNNFKTFRKVPYPGAGQLPYIIGGSDLVAHQARKNSELEEWLREELEEQNRRAREESLADDLFRYDPNVKRRR
What is the function of this protein?
Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity (PubMed:12422221).  The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis (PubMed:12422221).  The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11 (By similarity).  RAD50 may be required to bind DNA ends and hold them in close proximity (By similarity).  NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions (By similarity).  It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX (By similarity).  NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation (By similarity).  NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints (By similarity).  The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability (By similarity).  Forms a complex with RBBP8 to link DNA double-strand break sensing to resection (By similarity).
What are the official names of this protein?
Nibrin, Nijmegen breakage syndrome protein 1 homolog.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: HIS5_MYCBO
Sequence: MTAKSVVVLDYGSGNLRSAQRALQRVGAEVEVTADTDAAMTADGLVVPGVGAFAACMAGLRKISGERIIAERVAAGRPVLGVCVGMQILFACGVEFGVQTPGCGHWPGAVIRLEAPVIPHMGWNVVDSAAGSALFKGLDVDARFYFVHSYAAQRWEGSPDALLTWATYRAPFLAAVEDGALAATQFHPEKSGDAGAAVLSNWVDGL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTC_ECO55
Sequence: MDQKQIEEIVRSVMASMGQTAPAPSEAKCATTNCAAPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: RAD52_KLULA
Sequence: MEDTGSGKNGKDDIQTKLDKKLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGYDGWSTEVKNVTIDFLDERQGRFSIGCTAIVRVSLADGTFREDIGYGTVENERRKASAFERAKKSAVTDALKRSLRGFGNALGNCLYDKDFLAKIDKVKFDPPDFDEGNLFRPADELSEMSRSNMVGDAHTEGPSLKKRSLTNEDRNAVPSAPAQQTYRSNNHTTQKRAPKAQAVTASASPNEETSNQQQDPDDLLDDSFMFSDEIQDDDLLNMNTTTNNKNSTNSSTTTTTISDEATGIISPVTFVTAKAATSLQHKDPIPSGSMFDPKFQAQSIRHTVDQSVSTPVRATILKEKGLDSDRSSIYSKFAPKGKELSGTTTNSEPYVAAPQTSATESNRSTPTRSNAQLAGPQPAPQLQGPQRTQLGRPRMLQQPNRRNVS
What is the function of this protein?
Involved in DNA double-strand break (DSB) repair and recombination.  Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RAD52.
What is the protein family that this protein belongs to?
Belongs to the RAD52 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FIMP_MOUSE
Sequence: MKLWLWVAVGVWMLMAELGTIETAPRRDGTRPSVSGARPQQVVNRLFFDYPDSDRASLLAVARFIGEKPITFVKTDSSPGLFQNILVGTLVVAFFFLLFQFCLHVNFQKGA
What is the function of this protein?
Plays a role in sperm-oocyte fusion process during fertilization.
What are the official names of this protein?
Fertilization-influencing membrane protein.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Note=Localized to the equatorial segment of the sperm head. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: MAZF_STAES
Sequence: MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIRTLDKKRLKEKLTFLSESKMIEVDNALDISLGLNNFDHHKS
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis.  It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA.  Neutralized by coexpression with cognate antitoxin MazE.
What are the official names of this protein?
Endoribonuclease MazF, Toxin MazF, mRNA interferase MazF.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: MANC7_ECOLX
Sequence: MSSPLIPVILSGGNGTRLWPLSREEYPKQFLKLTDSISMLQSTISRLDSLNTSSPVVICNELHRFIVAEQLRHLNKLDNNIILEPSGRNTAPAICIAALILKMKHPNENPLMLVLPADHSVKKVKTFCNTIKSAIPFAEAGNLVSFGIKPTHPETGYGYIQKGKVLSDSDIYEVSEVRTFVEKPNLKTAESFIEKDEYYWNSGMYLFSVERYLQELSLYRPDIVKVCQETVKNIHYDMDFIRLDDKIFRNCPQESIDYAVMEKTKDAVVATMDIGWNDVGAWSSLWELGKKDSSGNVITGDIVCHETENSYIYTESGLVATIGIQDLVIIHTKDSLLVSRRDSVQNVKNIVQHLDLSGRKEHKEHREVFKSWGRCDSIDSSEKYHYQVKRITVNPSENYRCNYIITVRNIGVVVMGIAKLTVAEEIKILKENESVYIPAGIKHSLKILDNTTCVNRSLDRFLSC
What is the function of this protein?
Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides.  This enzyme participates in synthesis of the LPS O7 antigen.
What are the official names of this protein?
Mannose-1-phosphate guanylyltransferase, GDP-mannose pyrophosphorylase, GMP, GMPP.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 2 family.
Protein: METK_BORPE
Sequence: MANNDFLFTSESVSEGHPDKVADQISDAILDAIFTQDPNARVAAETLCNTGLVVLAGEITTTANVDYIQVARDTIRHIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVDRSSEDYLNQGAGDQGLMFGYACDETPDLMPAPIWYAHRLVQRQSELRKDGRLPWLRPDAKSQVTFRYVDGRPAEVDTVVLSTQHSPEISQASIREAVIEDIIKPSFPEGLITPKTKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQCQVQVSYAIGVAEPINITVYTEGTGVIPDEQIAKLVREHFDLRPKGIVNMLDLLRPIYTKTAAYGHFGRSEPEFSWEATDKAAALKQGA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_CHLAB
Sequence: MKEKTTQLYEGAYVFSVTLSEEARRKALEKVTSGITNYGGEILKIHDQGRKKLAYTIRGAREGYYYLIYFTVVPGVIAELWKEYHLNEDLLRFLTLKTDAVKEVLEFASLPE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PEPT_SALNS
Sequence: MDKLLERFLHYVSLDTQSKSGVRQVPSTEGQWKLLRLLKQQLEEMGLVNITLSEKGTLMATLPANVEGDIPAIGFISHVDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGVAEIMTALAVLKGNPIPHGDIKVAFTPDEEVGKGAKHFDVEAFGAQWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADEAPETTEGYEGFYHLASMKGTVDRAEMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCHITPEMKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAKRGQ
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FD3_DROME
Sequence: MHTSTDPMHTLHDSVSLSPPLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIEPSSMGGSGAAGGNGDGSGSSGGPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWIRKPVPLVPVHFNVPNFNGSREFDVVHNPADVFDSALRADKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSKYKSPYAFDVATVASAAGIPGHRDYAERLSAGGGYMDLNVYNDDADTEADAEAEGDDDSCEDKIDVESGNEQEDSHISDSVDSACTNRLDAPPEALIFEASAEASDSSPRRRFDSEPLVLRTSKQSSAKDFRIETLIGHHLHRGGSQEETSD
What is the function of this protein?
Involved in development during embryogenesis.
What are the official names of this protein?
Fork head domain-containing protein FD3.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTHS_MOOTH
Sequence: MSKVPSDIEIAQAAKMKPVMELARGLGIQEDEVELYGKYKAKISLDVYRRLKDKPDGKLILVTAITPTPAGEGKTTTSVGLTDALARLGKRVMVCLREPSLGPSFGIKGGAAGGGYAQVVPMEDINLHFTGDIHAVTYAHNLLAAMVDNHLQQGNVLNIDPRTITWRRVIDLNDRALRNIVIGLGGKANGVPRETGFDISVASEVMACLCLASDLMDLKERFSRIVVGYTYDGKPVTAGDLEAQGSMALLMKDAIKPNLVQTLENTPAFIHGGPFANIAHGCNSIIATKTALKLADYVVTEAGFGADLGAEKFYDVKCRYAGFKPDATVIVATVRALKMHGGVPKSDLATENLEALREGFANLEKHIENIGKFGVPAVVAINAFPTDTEAELNLLYELCAKAGAEVALSEVWAKGGEGGLELARKVLQTLESRPSNFHVLYNLDLSIKDKIAKIATEIYGADGVNYTAEADKAIQRYESLGYGNLPVVMAKTQYSFSDDMTKLGRPRNFTITVREVRLSAGGRLIVPITGAIMTMPGLPKRPAACNIDIDADGVITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: DCUP_ACIBS
Sequence: MTTLKNDRFLRALLREPVDTTPIWMMRQAGRYLPEYRETRSKAGDFLSLCKNTEFACEVTLQPLRRYDLDAAILFSDILTIPDALGLGLYFETGEGPKFHKTVRTEQDVANLPKLNAKADLDYVMNAVSTIRSALGGQVPLIGFSGSPWTLATYMVEGGSSKEFRFTKQMMYAQPEVLHALLDHLADSVIDYLNAQIDAGAQAIQIFDSWGGALAHREYVEFSLNYMNKIIAGLQREKDGRRIPVIVFTKGGGQWLEPMITTGADALGLDWTTPLNTARNVVSGRVALQGNLDPAVLYGSAASIEKAVKAMLDDAYANGEKTGYVANLGHGITQWVDPAQPKIFVDTVHEYSAKYLG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.